bluuebunny/crossref_metadata_2025_split huggingface dataset:
Geographical distribution of emergency obstetric and neonatal care signal functions in Ethiopian health facilities: 2021–2022 Ethiopian service Provision Assessment (SPA)
Authors: Dinagde Dagne Deresa , Wada Habtamu Wana 
Published: April 2024

Abstract
Background
The maternal mortality ratio in Ethiopia is still high, with an estimate of 412 deaths per 100,000 live births in 2016. Signal functions for emergency obstetric and neonatal care must be accessible and usable in order to successfully prevent maternal deaths. It is an important strategy to reduce maternal and newborn morbidity and mortality in countries with limited resources. Hence, an assessment of the availability of fully functioning EmONC services and their coverage per 500,000 people in Ethiopia is crucial.

Methods
This study is a retrospective analysis of data from the Ethiopian Service Provision Assessment Survey (ESPA), a national-level survey data source. Data collection for the survey took place from August 11, 2021, to February 4, 2022. For this investigation, 905 healthcare facilities in total were evaluated for the availability of emergency obstetric and new-born care (EmONC) services at all hospitals, selected health centers, and private clinics were evaluated. Descriptive data analysis was done by the using statistical package for social science version 26 (SPSS) to run frequency and cross-tabs. Global Positioning System (GPS) (arc map 10.8) Software was used for spatial distribution in order to locate the physical accessibility of EmONC providing health facilities on flat map surfaces. It was projected based on Ethiopia’s geographic coordinate system at Adindan UTM zone 370N.

Results
Of 905 health facilities, only 442 (49%) could provide fully functioning BEmONC, and 250 (27.6%) health facilities have been providing fully functioning CEmONC. The overall coverage of BEmONC ratios in Ethiopia is 1.5–3.77 per 500,000 population and CEmONC (0.83–2.1) per 500,000 populations. Regions such as Amhara, SNNPR and Addis Ababa had found to have high BEmONC ratio. The geographical distribution of the EmONC showed that the central areas of the country, such as southwest Shewa and east Shewa, the Oromia region, the northern areas of the South Nation, nationalities, and peoples regions (SNNPR), including the Gurage zone and the Wolaita-Soddo zone, and the middle areas in the Amhara region (west Gojjam or around Bahir Dar town), and the southern areas, Debra Tabor and Debre Birhane zones, all had greater access to facilities offering complete EmONC services.

Conclusion
Comprehensive emergency obstetrics and neonatal care (CEmONC) in Ethiopia met WHO recommendations, despite basic emergency obstetric and neonatal care (BEmONC) falling below those standards in Ethiopia. There are extremely large disparities in the accessibility of both basic and comprehensive emergency obstetrics and neonatal care in Ethiopia. Thus, Strategic planning is needed to improve infrastructures and inputs for EmONC services, particularly in remote areas of the country. Additionally, private facilities ought to place a priority on the provision of these services.
Association between days for concussion recovery and initial specialty clinic evaluation within 48 hours
Authors: Mathew Abel S. , Caze Todd , Price August M. , Vasquez Desi , Abt John P. , Burkhart Scott O. 
Published: April 2024

Abstract
Background
Researchers have highlighted the importance of early access to concussion care within one week of injury in reducing recovery times. However, a persisting question for concussion researchers is “just how early is important?” The purpose of this study was to examine differences in recovery time as predicted by the number of days elapsed since injury (DSI) to initial evaluation among patients who had access to a specialty concussion clinic within seven days. We hypothesized that DSI group membership, even within seven days, would significantly predict risk of protracted recovery (i.e., beyond 21 days).

Methods
In this archival study, retrospective data were gathered from electronic medical records between September 2020 to March 2022. Records of participants between ages 12–18, those diagnosed with a sports-related concussion based on initial clinic visit diagnosis by a medical provider and those who established care within seven days of injury at a large pediatric specialty concussion clinic were examined. Participants were divided into three DSI groups (patients seen in < 48 h: “acute”, patients seen between 49 h < and < 96 h: “sub-acute”, and patients seen between 97 < and < 168 h: “post-acute”). A general linear model was constructed to examine relationships between relevant concussion factors (e.g., Post Concussion Scale Score, neurodevelopmental history, psychiatric history, concussion history, migraine history, overall VOMS change score, cognitive testing, sex, age, race, and ethnicity) that were either significant in the preliminary analysis or in clinical judgement and recovery time. Adjusted odds ratios (OR) were derived from a binary logistic regression model, in which recovery time was normal (≤ 21 recovery days) or protracted (> 21 recovery days).

Results
A total of 856 participants were eligible. Adolescents in the acute group (M = 15.12, SD = 8.04) had shorter recovery times in days compared to those in the sub-acute (M = 17.98, SD = 10.18) and post-acute (M = 21.12, SD = 10.12; F = 26.00, p < .001) groups. Further, participants in the acute (OR = 4.16) and sub-acute (OR = 1.37) groups who accessed specialty concussion clinics within 48 h were 4 times more likely to have a normal recovery and recovered approximately 6 days faster than the post-acute care group.

Conclusions
Earlier concussion care access predicted recovery times and was associated with lower risk for protracted recovery.
First record of Psorophora ferox (Diptera: Culicidae) infested with eggs of Dermatobia hominis (Diptera: Cuterebridae), in Ucayali: Peru
Authors: Requena-Zúñiga Edwin , Chapilliquen-Alban Fernando , Leon-Cueto Walter , Bances-Juarez Fredy , Valle-Toledo Jorge , Rojas-Jaimes Jesús 
Published: April 2024

Abstract
Introduction
Dermatobia hominis belongs to the Cuterebridae family, Diptera order; These flies inhabit tropical regions where they are called "fly of death" since the larvae are capable of causing lesions in domestic animals, wild animals including humans, the adult females of D. hominis capture other dipteran to oviposit their eggs on them (phoresis), when hematophagous mosquitoes land on an animal and / or human in order to feed on their blood, the eggs hatch and the larvae immediately penetrate the skin where they will develop to later abandon the host, then in the soil and / or other moist substrate the pupal stage develops, finally new adult flies will emerge from the pupae.

Objective
The primary goal of the present study was to determine as first record, the presence of Psorophora ferox infested with eggs of Dermatobia hominis, Peru.

Methodology
The present study was carried out in an area of the private reserve "El Vencedor", located within the city of Pucallpa, Ucayali Region-Perú. The area is characterized by being humid tropical, with an average temperature of 26ºC and humidity of 92%, while the annual precipitation is approximately 1570 mm3. The capture method was carried out with the help of a hand net type "butterfly" or also called Jama.

Results
A total of 668 mosquitoes of different species were collected, the most abundant being Psorophora albigenu and Psorophora ferox, which represented 88.72% and the least abundant was Culex coronator and Uranotaenia apicalis with 0.15% of the total sample collected.

Conclusions
Within these specimens it was captured a mosquito of the species Ps. ferox with the presence of 8 eggs of D. hominis, of which 3 would have hatched, while in the remaining 5, the larvae would remain inside the eggs.
The long-term cost-effectiveness of once-weekly semaglutide versus sitagliptin for the treatment of type 2 diabetes in China
Authors: Gu Shuyan , Gu Jinghong , Wang Xiaoyong , Wang Xiaoling , Li Lu , Gu Hai , Xu Biao 
Published: April 2024

Abstract
Background
To estimate the long-term cost-effectiveness of once-weekly semaglutide versus sitagliptin as an add-on therapy for type 2 diabetes patients inadequately controlled on metformin in China, to better inform healthcare decision making.

Methods
The Cardiff diabetes model which is a Monte Carlo micro-simulation model was used to project short-term effects of once-weekly semaglutide versus sitagliptin into long-term outcomes. Short-term data of patient profiles and treatment effects were derived from the 30-week SUSTAIN China trial, in which 868 type 2 diabetes patients with a mean age of 53.1 years inadequately controlled on metformin were randomized to receive once-weekly semaglutide 0.5 mg, once-weekly semaglutide 1 mg, or sitagliptin 100 mg. Costs and quality-adjusted life years (QALYs) were estimated from a healthcare system perspective at a discount rate of 5%. Univariate sensitivity analysis, scenario analysis, and probabilistic sensitivity analysis were conducted to test the uncertainty.

Results
Over patients’ lifetime projections, patients in both once-weekly semaglutide 0.5 mg and 1 mg arms predicted less incidences of most vascular complications, mortality, and hypoglycemia, and lower total costs compared with those in sitagliptin arm. For an individual patient, compared with sitagliptin, once-weekly semaglutide 0.5 mg conferred a small QALY improvement of 0.08 and a lower cost of $5173, while once-weekly semaglutide 1 mg generated an incremental QALY benefit of 0.12 and a lower cost of $7142, as an add-on to metformin. Therefore, both doses of once-weekly semaglutide were considered dominant versus sitagliptin with more QALY benefits at lower costs.

Conclusion
Once-weekly semaglutide may represent a cost-effective add-on therapy alternative to sitagliptin for type 2 diabetes patients inadequately controlled on metformin in China.
A novel outlier detection method based on Bayesian change point analysis and Hampel identifier for GNSS coordinate time series
Authors: Pehlivan Hüseyin 
Published: April 2024

AbstractThe identification and removal of outliers in time series are important problems in numerous fields. In this paper, a novel method (BCP-HI) is proposed to enhance the accuracy of outlier detection in GNSS coordinate time series by combining Bayesian change point (BCP) analysis and the Hampel identifier (HI). By using BCP, change points (cps) in the time series are lidentified, and so the time series is divided into subsegments that have properties of a normal distribution. In each of these separated segments, outliers are detected using HI. Each data element identified as an outlier is corrected by a median filter of window size (w) to obtain the corrected signal. The BCP-HI method was tested on both simulated and real GNSS coordinate time series. Outliers from three different synthetic test datasets with different sampling frequencies and outlier amplitudes were detected with approximately 98% accuracy after processing. After this process, Signal-to-Noise Ratio (SNR) increased from 0.0084 to 10.8714 dB and Root Mean Square (RMS) decreased from 24 to 23 mm. Similarly, for real GNSS data, approximately 98% accuracy was achieved, with an increase in SNR from 0.0003 to 4.4082 dB and a decrease in RMS from 7.6 to 6.6 mm observed. In addition, the output signals after BCP-HI were examined graphically using Lomb–Scargle periodograms and it was observed that clearer power spectrum distributions emerged. When the input and output signals were examined using the Kolmogorov–Smirnov (KS) test, they were found to be statistically similar. These results indicate that the BCP-HI algorithm effectively removes outliers, and enhances processing accuracy and reliability, and improves signal quality.
Gender health care inequalities in health crisis: when uncertainty can lead to inequality
Authors: Aguilar-Palacio Isabel , Obón-Azuara Blanca , Castel-Feced Sara , Malo Sara , Teresa Julia , Rabanaque María José 
Published: April 2024

Abstract
Background
In health crisis, inequalities in access to and use of health care services become more evident. The objective of this study is to analyse the existence and evolution of gender inequalities in access to and use of healthcare services in the context of the COVID-19 health crisis.

Methods
Retrospective cohort study using data from all individuals with a confirmed COVID-19 infection from March 2020 to March 2022 in Aragón (Spain) (390,099 cases). Health care access and use was analysed by gender for the different pandemic waves. Univariate and multivariate analyses were conducted to evaluate the effect of sex in health care. Blinder-Oaxaca decomposition methods were performed to explain gender gaps observed.

Results
The health care received throughout the COVID-19 pandemic differed between men and women. Women were admitted to hospital and intensive care units less frequently than men and their stays were shorter. Differences observed between men and women narrowed throughout the pandemic, but persisted even after adjusting for age, socioeconomic status, morbidity burden or the patient's place of residence. Differences in sociodemographic characteristics and morbidity burden could explain partially the gender inequalities found, mainly in the later phases of the pandemic, but not in the earlier waves.

Conclusions
There were gender inequalities in access to and use of health services during the COVID-19 pandemic. Inequalities were greater in the first waves of the pandemic, but did not disappear. Analysis of health crises must take into account an intersectional gender perspective to ensure equitable health care.
Factors associated with anemia among reproductive age women in Nigeria; evidenced by the Nigeria malaria indicators survey: spatial and multilevel model analysis
Authors: Mankelkl Gosa , Kinfe Beletu 
Published: April 2024

Abstract
Background
Anemia is a global public health problem among women of reproductive age group, especially in developing countries, which affect health, social and economic development that result in low physical activity, increased maternal morbidity and mortality and adverse neonatal outcome especially those with severe anemia. However, there is limited reliable and updated data on the spatial variations of anemia and its associated factors among reproductive-age women in Nigeria.

Methods
Secondary data analysis was conducted using data from the recent Nigeria malaria indicators survey datasets. The study comprised a total of 14,476 reproductive-age women. Spatial and multilevel mixed effect analysis on determinants factors of anemia among reproductive age women in Nigeria evidenced by the recent Nigerian malaria indicators survey. Finally, the percentage and odd ratio, its 95% confidence intervals, and the result of spatial analysis were reported.

Result
This study includes a total weighted sample of 14,476 reproductive-age women from the Nigeria malaria indicators survey. The prevalence of anemia was 24.6% in Ethiopia. Being between the age range of 30–34 years [AOR: 0.217, 95% CI (0.171, 0.274)], Attending higher education [AOR: 0.848, 95%CI (0.740, 0.972)] and being male headed household [AOR: 0.540, 95% CI (0.471, 0.620)] were protective for anemia. On the other hand being poorest [AOR: 1.542 95%CI (1.299, 1.830)] and being listening radio less than once a week [AOR: 1.013, 95% CI (0.908, 1.131)] were risk for anemia.

Conclusion
In this study Individual level factors were associated with anemia and also there were spatial variations in anemia across the region among reproductive-age women. Empowering women to have better educational status, improving the wealth index, and promoting education about prevention and control strategies of anemia through media especially in developing regions were the key factors to reduce anemia among reproductive age women in Nigeria.
Phenotype-considered kinematically aligned total knee arthroplasty for windswept-deformity-associated osteoarthritis: surgical strategy and clinical outcomes
Authors: Hsu Cheng-En , Tsai Meng-Hsueh , Wu Hsin-Ting , Huang Jen-Ting , Huang Kui-Chou 
Published: April 2024

Abstract
Background
Windswept deformity (WSD) in relation to advanced osteoarthritis (OA) presents a significant surgical challenge in total knee arthroplasty (TKA). The primary goal of this study is to investigate the Prevalance of WSD associated osteoarthritis who have undergone total knee arthroplasty. The secondary goal is to explore the causes of WSD and its association with spinal deformity or leg length discrepancy in these patients. Finally, we evaluate the surgical outcomes of phenotype-considered kinematically aligned TKA (KA-TKA) in treating patients with WSD.

Methods
A review was conducted on data from 40 knees of 33 WSD patients who underwent phenotype-considered KA-TKA from August 2016 to December 2020. Patient demographics, associated diseases, preoperative and postoperative knee alignment angles, range of motion (ROM), Oxford Knee Score (OKS), and Knee Society Score (KSS) were collected and analyzed. Subgroup analysis for comparing the results between valgus and varus knees were also performed.

Results
Within the studied cohort of WSD patients, a substantial 64% displayed concomitant coronal spinal imbalance and 21% evidenced leg length discrepancy. Postoperative improvements were notable in knee alignments, ROM, OKS, and KSS following the application of the phenotype-considered KA-TKA approach. There were significant differences in the knee alignment angles, including mHKA, LDFA, and MPTA, between the valgus and varus side of knees (P = 0.018). However, no statistically significant difference were observed in the functional scores, comprising ROM, OKS, and KSS, between valgus and varus knees.

Conclusions
A high percentage of patients with WSD exhibited coronal spinal imbalance and leg length discrepancy. Phenotype-considered KA-TKA effectively provided alignment targets for the treatment of both varus and valgus knees in patients with WSD, achieving excellent short-term outcomes and acceptable knee alignment.
Non-linear vibration and bifurcation analysis of Euler-Bernoulli beam under parametric excitation
Authors: Liao Pengtai 
Published: April 2024

AbstractThis paper presents an analysis of the non-linear vibrations of beams, which play a crucial role in various industrial and construction structures. Understanding the transverse vibrations of beams and accurately determining their frequency response is essential for achieving optimal design and structural performance. The novelty of this study lies in conducting a transverse non-linear vibration analysis of a three-dimensional beam while considering the effect of mid-plane elongation. By incorporating this aspect into the analysis, the study aims to provide deeper insights into the dynamic behavior of beams subjected to non-linear effects. A multiple-time scale approach has been adopted to conduct this research. To verify the accuracy of the method as well as the accuracy of the outcomes gained from this method, a contrast has been made with the 4th-order Runge-Kutta technique, which indicates that the results obtained are acceptable. The frequency response of the beam indicates the presence of a phenomenon of splitting into two non-linear branches during the three-dimensional vibrations of the beam, as well as a hardening state in the frequency response as a result of stretching the middle plane of the beam. Furthermore, a parametric study was conducted in which different parameters were examined to determine the starting point of non-linear bifurcation. As a result, the damping coefficient and resonance deviation parameter are two factors that affect the preference for critical bifurcation over safe bifurcation. Furthermore, the stretching of the middle plane results in a higher non-linear term coefficient in the vibration equations of the beam, which increases the oscillation frequency of the beam.
Identification of Pancreatic Cancer Germline Risk Variants With Effects That Are Modified by Smoking
Authors: Zhu Huili , Choi Jaihee , Kui Naishu , Yang Tianzhong , Wei Peng , Li Donghui , Sun Ryan 
Published: April 2024

PURPOSE Pancreatic cancer (PC) is a deadly disease most often diagnosed in late stages. Identification of high-risk subjects could both contribute to preventative measures and help diagnose the disease at earlier timepoints. However, known risk factors, assessed independently, are currently insufficient for accurately stratifying patients. We use large-scale data from the UK Biobank (UKB) to identify genetic variant-smoking interaction effects and show their importance in risk assessment. METHODS We draw data from 15,086,830 genetic variants and 315,512 individuals in the UKB. There are 765 cases of PC. Crucially, robust resampling corrections are used to overcome well-known challenges in hypothesis testing for interactions. Replication analysis is conducted in two independent cohorts totaling 793 cases and 570 controls. Integration of functional annotation data and construction of polygenic risk scores (PRS) demonstrate the additional insight provided by interaction effects. RESULTS We identify the genome-wide significant variant rs77196339 on chromosome 2 (per minor allele odds ratio in never-smokers, 2.31 [95% CI, 1.69 to 3.15]; per minor allele odds ratio in ever-smokers, 0.53 [95% CI, 0.30 to 0.91]; P = 3.54 × 10−8) as well as eight other loci with suggestive evidence of interaction effects ( P < 5 × 10−6). The rs77196339 region association is validated ( P < .05) in the replication sample. PRS incorporating interaction effects show improved discriminatory ability over PRS of main effects alone. CONCLUSION This study of genome-wide germline variants identified smoking to modify the effect of rs77196339 on PC risk. Interactions between known risk factors can provide critical information for identifying high-risk subjects, given the relative inadequacy of models considering only main effects, as demonstrated in PRS. Further studies are necessary to advance toward comprehensive risk prediction approaches for PC.
Obraz drugiej wojny światowej w utworach pisarzy emigracyjnych kierowanych do młodego czytelnika
Authors: Wróblewski Maciej 
Published: April 2024

Celem artykułu jest analiza w kontekście historycznym zarówno powieści dla dzieci, jak i młodzieży, opowiadań i opowiadań poświęconych II wojnie światowej, napisanych przez emigracyjnych pisarzy. Utwory Anatola Krakowieckiego, Ryszarda Kiersnowskiego, Jana Lechonia, w odmienny sposób przedstawiają obraz czasu wojny niż autorzy publikujący w Polsce. Pisarze emigracyjni podkreślają własne doświadczenie związane z wychodźstwem, które wiąże się z ich życiem prywatnym w czasie II wojny światowej. Następnie umieszczają oni swoje historie zarówno w okupowanej Polsce, jak i w obcych krajach, w których wraz z aliantami Polacy walczyli z nazistami (np. Egipt, Anglia, Norwegia, Francja). Analizowane w tym artykule utwory, Lechonia Historia o jednym chłopczyku i o jednym lotniku, Lisiewicza Gdzie goręcej biją serca i Czarne żórawie Krakowieckiego ukazują Rosję i Armię Czerwoną jako wrogów Polski. Ponadto autorzy ci wspominali w swoich tekstach o inwazji Armii Czerwonej na ziemie polskie 17 września 1939 r. Literatura emigracyjna o II wojnie światowej dla dzieci i młodzieży jest swoistym porozumieniem międzypokoleniowym, zawierającym wyraziste znamiona nostalgii.