bluuebunny/crossref_metadata_2025_split huggingface dataset:
Psychiatry and Family Medicine Residents’ Likelihood of Prescribing HIV Pre-Exposure Prophylaxis (PrEP) to Patients with Mental Illness and HIV Vulnerability
Authors: Bunting Samuel R. , Feinstein Brian A. , Vidyasagar Nitin , Sheth Neeral K. , Yu Roger , Hazra Aniruddha 
Published: April 2024

Background:
People living with mental illness (PLMI) experience disproportionately high incidence of and vulnerability to HIV. Pre-exposure prophylaxis (PrEP) is an effective and safe HIV prevention method, but data regarding prescription to PLMI are lacking. Psychiatrists may serve as important points of access for PrEP prescription for PLMI.

Methods:
We conducted a vignette-based study of residents in psychiatry and family medicine (FM) to assess likelihood of prescribing PrEP and assumptions about the fictional patient. The patients’ psychiatric diagnosis was varied (schizophrenia on LAI or oral antipsychotic, bipolar disorder, major depression) or a control condition without a psychiatric diagnosis.

Results:
A total of 439 residents participated. We found high percentages of psychiatry (96.8%) and FM (97.4%) residents were aware of PrEP. High percentages of psychiatry (92.0-98.1%) and FM (80.8-100%) residents indicated that PrEP was indicated for all patient conditions. Family medicine residents were more likely to prescribe PrEP to all experimental conditions compared to psychiatry residents. There was no difference in likelihood of prescribing to the control condition without a psychiatric diagnosis. The belief that PrEP prescription was out of the scope of practice was greater among psychiatry residents.

Conclusions:
A majority of psychiatry residents responded that PrEP was indicated for an array of patients with psychiatric diagnoses. However, psychiatry residents were broadly less likely to prescribe PrEP to patients with these diagnoses. The high percentage of psychiatry residents who reported that PrEP was indicated for all patients suggests additional training is needed to facilitate PrEP prescription by psychiatrists.
95 GeV diphoton and
bb¯
excesses in the general next-to-minimal supersymmetric standard model
Authors: Cao Junjie , Jia Xinglong , Lian Jingwei , Meng Lei 
Published: April 2024

The CMS and ATLAS Collaborations recently published their results searching for light Higgs bosons, using the complete Run 2 data of the LHC. Both reported an excess in the diphoton invariant mass distribution at mγγ≃95.4  GeV with compatible signal strengths. The combined result corresponded to a local significance of 3.1σ. Besides, the mass of the diphoton signal coincided with that of the bb¯ excess observed at the Large Electron Positron. Given the remarkable theoretical advantages of the general next-to-minimal supersymmetric Standard Model, we interpret these excesses by the resonant productions of the singlet-dominated CP-even Higgs boson predicted by the theory. Using both analytic formulas and numerical results, we show that the idea can interpret the excesses by broad parameter space without contradicting current experimental restrictions, including those from the 125 GeV Higgs data, the dark matter relic abundance and direct detection experiments, and the collider searches for supersymmetry and extra Higgs bosons. Although the explanations are scarcely affected by present Higgs data and the LHC search for supersymmetry, the dark matter physics may leave footprints on them. We also survey the other signals of the light Higgs boson at the LHC.

Published by the American Physical Society
2024
Women leadership in higher education: past, present and future trends
Authors: Fauzi Muhammad Ashraf , Tan Christine Nya-Ling , Muhamad Tamyez Puteri Fadzline , Abd Aziz Nurul Ashykin , Wider Walton 
Published: April 2024

PurposeGender bias and stereotypes are universal issues in today’s society. This study presents a comprehensive review of women’s leadership based on bibliometric analysis. The feminist approach to leadership is helpful in many ways, and it could be the type of leadership needed in the challenging world of academia. Women present unique characteristics and traits, particularly their motherly approach to leadership.Design/methodology/approachA review of the literature based on bibliometric analysis by mapping the knowledge structure of the subject is conferred by uncovering the past, present and future trends based on three bibliometric analyses.FindingsThe finding suggests that gender equality, stereotypes and barriers in women’s leadership are at the forefront of the subject in HEIs. The overall system, mindset and willingness for institutional transformation are needed to change the mindset of accepting women as leaders of HEIs.Research limitations/implicationsThis study brought the significant idea of increasing women’s empowerment in HEIs, eventually strengthening institutional leadership’s capability towards advanced education.Originality/valueThis study would present a crucial foundation in women’s empowerment, particularly from the HEIs perspective and from the generic women’s leadership literature.
Co-creation solutions and the three Co’s framework for applying Co-creation
Authors: Pearce Gemma , Magee Paul 
Published: April 2024

PurposeA sense of collective free-thinking with tangible goals makes co-creation an enlightening experience. Yet despite the freedom and organic flow of the methodology, there remain barriers to deploying co-creation in the real-world context. The aim was to understand the barriers and solutions to co-creation, reflect on applying co-creation in practice and co-create an applicable framework for co-creation.Design/methodology/approachThese reflections and conceptual developments were completed using a Participatory Action Research Approach through the co-creation of the Erasmus+ funded Co-creating Welfare course.FindingsResults presented are centric to the experiences in the United Kingdom but led to application at an international level. Problem formulation led to solutions devised about who should co-create, what co-creation aims to achieve, how to receive management buy-in, co-creating beyond the local face to face context and evaluation.Originality/valueThe Three Co’s Framework is proposed using the outline of: Co-Define, Co-Design and Co-Refine. Those who take part in co-creation processes are recommended to be called co-creators, with less focus on “empowerment” and more about facilitating people to harness the power they already have. Utilising online and hybrid delivery methods can be more inclusive, especially in response to the COVID-19 pandemic. The use of co-creation needs to be evaluated more moving forwards, as well as the output co-created.
Undrained shear strength of soft clay reinforced with encapsulated stone dust columns
Authors: Hoque Md. Ikramul , Hasan Muzamir , Datta Shuvo Dip 
Published: April 2024

PurposeThe stone dust column was used to strengthen the sample and had a significant effect on improving the shear strength of the kaolin clay. The application of stone columns, which can improve the overall carrying capacity of soft clay as well as lessen the settlement of buildings built on it, is among the most widespread ground improvement techniques throughout the globe. The performance of foundation beds is enhanced by their stiffness values and higher strength, which could withstand more of the load applied. Stone dust is a wonderful source containing micronutrients for soil, particularly those derived from basalt, volcanic rock, granite and other related rocks. The aim of this paper is to evaluate the properties of soft clay reinforced with encapsulated stone dust columns to remediate problematic soil and obtain a more affordable and environmentally friendly way than using other materials.Design/methodology/approachIn this study, the treated kaolin sample's shear strength was measured using the unconfined compression test (UCT). 28 batches of soil samples total, 12 batches of single stone dust columns measuring 10 mm in diameter and 12 batches of single stone dust columns measuring 16 mm in diameter. Four batches of control samples are also included. At heights of 60 mm, 80 mm and 100 mm, respectively, various stone dust column diameters were assessed. The real soil sample has a diameter of 50 mm and a height of 100 mm.FindingsTest results show when kaolin is implanted with a single encased stone dust column that has an area replacement ratio of 10.24% and penetration ratios of 0.6, 0.8 and 1.0, the shear strength increase is 51.75%, 74.5% and 49.20%. The equivalent shear strength increases are 48.50%, 68.50% and 43.50% for soft soil treated with a 12.00% area replacement ratio and 0.6, 0.8 and 1.0 penetration ratios.Originality/valueThis study shows a comparison of how sample types affect shear strength. Also, this article provides argumentation behind the variation of soil strength obtained from different test types and gives recommendations for appropriate test methods for soft soil.
Environmental sustainability and information sharing related to delivery options in the B2B2C context of e-commerce: evidence from a survey
Authors: Belvedere Valeria , Kotzab Herbert , Martinelli Elisa Martina 
Published: April 2024

Purpose
This paper aims to explore the conditions in a business-to-business-to-consumer (B2B2C) context characterized by new technologies. Innovations enhance disintermediation and pursue sustainability goals that drive customers’ willingness to use eco-friendly delivery options, namely, parcel lockers – in e-commerce and their impacts in terms of communication and transparency along the supply network.

Design/methodology/approach
The study conducted an extensive survey in Italy and Germany, collecting 1,010 usable responses. Structural equation modelling was used to analyse the data with the aim of identifying the factors that drive customers’ willingness to use parcel lockers and the effect on customers’ behaviour as determined by the disclosure of information about the environmental performance of different delivery options.

Findings
The results highlight several factors affecting the willingness to use parcel lockers, namely, performance and effort expectancy, social influence, technology anxiety, hedonistic motivation and environmental knowledge. The results also demonstrate that the disclosure of information about the environmental performance of different delivery options influences customers’ behaviour.

Research limitations/implications
This paper faces several limitations, mostly related to the focus on just two countries, the use of cross-sectional data and the survey’s explicit reference to just one type of product. Nevertheless, the findings contribute to the discussion on the relevance of information sharing along the supply chain, providing favourable evidence in this regard. It also improves the stream of research concerning technology adoption in the context of e-commerce, highlighting factors that can lead consumers to use eco-friendly self-service technologies.

Practical implications
The results can support companies in understanding how they can design and manage the last mile of delivery to jointly achieve customer satisfaction, process efficiency and superior environmental performance.

Originality/value
This pioneering contribution studies the adoption of delivery solutions for e-commerce and its implications for the supply network.
The Eighteenth‐Century Mentor Book
Authors: Blunsden Laura 
Published: April 2024

AbstractThe modern definition and associations of the word ‘mentor’ — a guide or adviser to a less experienced person — can be traced back to François Fénelon's didactic novel, Les aventures de Télémaque, fils d'Ulysse (1699). The novel was one of the most widely read works of the eighteenth century, but its influence on British didactic literature has received little critical attention. This article explores the development of the mentor book, a subgenre within the guide tradition, which invoked deeply interpersonal and mutually affectionate nature of the mentoring relationship in their titles and personified the text as an adviser of the reader. Fénelon's characterization of the mentor figure was imitated in the mode of instruction and pedagogical strategy of these mentor books, which reflected changing perceptions of the didactic role of print on eighteenth‐century society and culture.
Aging and intraocular pressure homeostasis in mice
Authors: Li Guorong , van Batenburg‐Sherwood Joseph , Safa Babak N. , Fraticelli Guzmán Nina Sara , Wilson Andrea , Bahrani Fard Mohammad Reza , Choy Kevin , de Ieso Michael L. , Cui J. Serena , Feola Andrew J. , Weisz Tara , Kuhn Megan , Bowes Rickman Catherine , Farsiu Sina , Ethier C. Ross , Stamer W. Daniel 
Published: April 2024

AbstractAge and elevated intraocular pressure (IOP) are the two primary risk factors for glaucoma, an optic neuropathy that is the leading cause of irreversible blindness. In most people, IOP is tightly regulated over a lifetime by the conventional outflow tissues. However, the mechanistic contributions of age to conventional outflow dysregulation, elevated IOP and glaucoma are unknown. To address this gap in knowledge, we studied how age affects the morphology, biomechanical properties and function of conventional outflow tissues in C57BL/6 mice, which have an outflow system similar to humans. As reported in humans, we observed that IOP in mice was maintained within a tight range over their lifespan. Remarkably, despite a constellation of age‐related changes to the conventional outflow tissues that would be expected to hinder aqueous drainage and impair homeostatic function (decreased cellularity, increased pigment accumulation, increased cellular senescence and increased stiffness), outflow facility, a measure of conventional outflow tissue fluid conductivity, was stable with age. We conclude that the murine conventional outflow system has significant functional reserve in healthy eyes. However, these age‐related changes, when combined with other underlying factors, such as genetic susceptibility, are expected to increase risk for ocular hypertension and glaucoma.
Efficacy of immune checkpoint inhibitors in advanced non‐small cell lung cancer patients with KRAS mutations: A network meta‐analysis
Authors: Zhang Lin , Chen Wei , Wei Hongtao , Yu Junxian 
Published: April 2024

AbstractObjectivePrevious studies have shown that immune checkpoint inhibitors can improve the survival of patients with advanced non‐small cell lung cancer with KRAS mutations; however, there is a lack of comparisons between treatment regimens associated with immune checkpoint inhibitors, and our study aims to compare several treatment parties to find a more effective treatment regimen.MethodA comprehensive literature search was conducted across multiple databases, namely PubMed, Web of Science, Embase, and Cochrane Library, to identify relevant studies. The screened studies were thoroughly examined, and data were collected to establish a Bayesian framework. The study focused on two primary endpoints: overall survival (OS) and progression‐free survival (PFS). Data analysis and graphical plotting using R software and Revman (version 5.3). It is worth mentioning that the study protocol was registered with the International Prospective Registry for Systematic Reviews, ensuring transparency and adherence to predetermined protocols (CRD42022379595).ResultIn total, our analysis included six RCTs involving 469 patients with KRAS mutations. Among these patients, 224 received chemotherapy, while 245 were treated with immune checkpoint inhibitors. Meta‐analysis results showed that the addition of ICIs could significantly improve OS and PFS (0.69, 95% CI 0.55, 0.86; 0.57, 95% CI 0.42, 0.77). The results of the network meta‐analysis showed that Pembrolizumab could improve OS (HR 0.42, 95% CI 0.22–0.80) and Pembrolizumab emerged as the most effective treatment option for enhancing OS in patients (SUCRA 65.03%). Additionally, pembrolizumab in combination with chemotherapy showed improvement in PFS (HR 0.47, 95% CI 0.29–0.76).ConclusionOur analysis found that among advanced NSCLC patients with KRAS gene mutations, first‐line treatment with pembrolizumab alone demonstrated greater efficacy. Similarly, second‐line treatment with nivolumab alone was found to be more effective in this patient population. However, the sample size of this study was limited, Therefore, additional clinical data is necessary to validate this finding in subsequent research.
Mortgage rates and credit risk: Evidence from mortgage pools
Authors: Antinolfi Gaetano , Brunetti Celso , Im Jay 
Published: April 2024

AbstractIn the 1990s, securitised subprime loans supported the growth of mortgage lending. We study the evolution of initial mortgage rates as a function of loan and borrower characteristics during 1992–2015. We compare the evolution of initial rates on securitised subprime mortgages with rates of prime privately securitised mortgages, mortgages securitised by government‐sponsored enterprises, and nonsecuritised mortgages. Starting in 2003 the risk premium on subprime loans decreases until it disappears at the onset of the Global Financial Crisis. We find that loading factors on subprime rates are cointegrated with delinquencies and house price movements, providing evidence of the important role of the subprime market.
Association between proactive esophageal cooling and increased lab throughput
Authors: Zagrodzky William , Cooper Julie , Joseph Christopher , Sackett Matthew , Silva Jose , Kuk Richard , McHugh Julia , Brumback Babette , Park Shirley , Hayward Robert , Taneja Taresh , Vu Andrew , Liu Taylor , Kulstad Erik , Kaplan Andrew , Ramireddy Archana , Omotoye Samuel 
Published: April 2024

AbstractIntroductionProactive esophageal cooling has been FDA cleared to reduce the likelihood of ablation‐related esophageal injury resulting from radiofrequency (RF) cardiac ablation procedures. Data suggest that procedure times for RF pulmonary vein isolation (PVI) also decrease when proactive esophageal cooling is employed instead of luminal esophageal temperature (LET) monitoring. Reduced procedure times may allow increased electrophysiology (EP) lab throughput. We aimed to quantify the change in EP lab throughput of PVI cases after the introduction of proactive esophageal cooling.MethodsEP lab throughput data were obtained from three EP groups. We then compared EP lab throughput over equal time frames at each site before (pre‐adoption) and after (post‐adoption) the adoption of proactive esophageal cooling.ResultsOver the time frame of the study, a total of 2498 PVIs were performed over a combined 74 months, with cooling adopted in September 2021, November 2021, and March 2022 at each respective site. In the pre‐adoption time frame, 1026 PVIs were performed using a combination of LET monitoring with the addition of esophageal deviation when deemed necessary by the operator. In the post‐adoption time frame, 1472 PVIs were performed using exclusively proactive esophageal cooling, representing a mean 43% increase in throughput (p < .0001), despite the loss of two operators during the post‐adoption time frame.ConclusionAdoption of proactive esophageal cooling during PVI ablation procedures is associated with a significant increase in EP lab throughput, even after a reduction in total number of operating physicians in the post‐adoption group.
Do end‐of‐life outcomes differ by assisted living memory‐care designation?
Authors: Wang Xiao(Joyce) , Cornell Portia Y. , Belanger Emmanuelle , Thomas Kali S. 
Published: April 2024

AbstractBackgroundResidential care/assisted living (RC/AL) is an increasingly common place of end‐of‐life care for persons with Alzheimer's disease and related dementia (ADRD), who have unique care needs as their health declines. Approximately 22% of RC/ALs provide specialized memory care (memory‐care RC/AL). Understanding how end‐of‐life outcomes differ by memory care among residents with ADRD could facilitate aging/dying in place for this population. The objective of this paper is to examine if end‐of‐life outcomes (i.e., mortality, hospice use, and number of days receiving hospice in the last month of life) differ between residents with ADRD who moved to memory‐care RC/AL, compared with residents with ADRD who moved to RC/AL without memory care (general RC/AL).MethodsProspective cohort of 15,152 fee‐for‐service Medicare beneficiaries with ADRD who moved to large RC/AL (> = 25 beds) between 2016 and 2018. We used inverse probability treatment weighting to account for observable differences between memory‐care and general RC/AL residents. Two‐part models estimated the difference by memory care in the number of days receiving hospice care in the last months of life among RC/AL decedents.ResultsThe unadjusted mortality rates were 13.4% in general RC/AL and 15.8% in memory‐care RC/AL with an adjusted difference of 1.3 percentage points higher mortality among memory‐care RC/AL residents (p = 0.04). Hospice use was 8% and 10.6% among general and memory‐care RC/AL residents, respectively, with an adjusted difference of 1.4 percentage points (p = 0.01) higher in memory care. Two‐part models showed that decedents in memory‐care RC/AL spent about 1.4 more days receiving hospice care in the last month of life (p = 0.02).ConclusionWe find a higher mortality rate and higher rate of hospice use among memory‐care RC/AL residents. These findings suggest that memory care may attract residents closer to the end of life and/or promote hospice use at the end of life.
The Couples' Closeness–Distance Scale– Observation through joint‐drawing: A pilot dyadic validation study
Authors: Egozi Sharon , Shalev Or , Svorai Lotem , Touch Ruth , Snir Sharon 
Published: April 2024

AbstractThe study aimed to evaluate the Couples' Closeness–Distance Scale (CCDS), an observational assessment reflecting couples' relational dynamics; based on joint‐drawing, it offers measurable dimensions. Forty cohabiting Israeli couples participated in the joint‐drawing task and answered self‐report questionnaires for attachment, differentiation of self, and relationship satisfaction. The paintings were assessed by trained observers on the CCDS scales (too distant, too close, autonomy, engagement) for both the women's and men's experiences. A two‐level‐dyadic model showed that differentiation and relationship satisfaction predicted the CCDS and revealed a “pursue–withdraw cycle”: Women sensed the men as too distant, while men sensed the women as too close. Participants' sense of discomfort from their partners' distance related to less autonomy and engagement during the painting, with a greater effect on the women. The pilot implies that the CCDS enables observing dyadic‐systemic aspects of couple dynamics and may enrich clinical evaluation.
Validation of the intersession alliance measure: Individual, couple, and family versions
Authors: Anderson Shayne R. , Johnson Lee N. , Witting Alyssa Banford , Miller Richard B. , Bradford Angela B. , Hunt Quintin A. , Bean Roy A. 
Published: April 2024

AbstractMonitoring the therapeutic alliance throughout treatment can improve client outcomes and lead to improved care. The individual, couple, and family versions of the intersession alliance measure (IAM) were developed to facilitate routine monitoring of the expanded therapeutic alliance. Psychometric properties of the three versions of the IAM were examined using a clinical sample. Participants were drawn from clinics in the United States participating in the Marriage and Family Therapy Practice Research Network. Using this sample, results indicate that items on each version of the IAM load on one factor, are invariant across sex, and that each version has good internal consistency, test–retest reliability, and concurrent validity. The IAM‐C and IAM‐F also have good predictive validity, while the IAM‐I has more limited evidence for its predictive validity. These results suggest that the IAMs are valid and reliable measures that can facilitate the routine monitoring of the expanded therapeutic alliance in psychotherapy.