bluuebunny/crossref_metadata_2025_split huggingface dataset:
Heavy metal concentrations and water quality assessment of different types of drinking water wells in the Erdenet Cu–Mo mining area
Authors: Munkhsuld Enkhuur , Murayama Takehiko , Fukushi Keisuke , Nishikizawa Shigeo , Gankhurel Baasansuren , Batbold Tserenkhand , Ochir Altansukh 
Published: February 2024

AbstractThe Erdenet mine (Erdenet, Mongolia) is a copper–molybdenum open pit mine with a huge tailing pond and is located next to a residential area. As the sources of drinking water in this area rely on groundwater and can be categorized into public or private wells, we aimed to assess the groundwater quality of the different types of drinking water wells. To accomplish our goal, we analyzed 18 trace metals (As, Ba, Bi, Cd, Co, Cr, Cs, Cu, Ga, Mo, Ni, Pb, Se, Sr, Th, U, V, Zn) and 8 major metals (Al, Ca, Fe, K, Mg, Mn, Na, Si) samples using ICP-MS and ICP-OES, and the heavy metal pollution index, heavy metal evaluation index, and degree of contamination were calculated. The most concerning point is that the Mo concentration of waste water in the Erdenet mine tailing pond and at a natural spring located 300 m from the tailing pond was 1100 μg/L, which greatly exceeds the WHO permissible concentration for Mo of 70 μg/L. Furthermore, high Ca and Mg concentrations at all private wells indicated that consumers of these wells are more vulnerable to any type of water pollution, as these wells are not built with any disinfection or treatment system. A modified categorization of the water quality indices showed that the public and private wells have low–medium contamination and that the tailing pond seepage water, along with its nearest spring, have a high degree of contamination. Because many private wells are located along the tailing pond and used directly without any treatment, we suggest a continuous evaluation and monitoring of the groundwater quality in this area.
Comparable outcomes with low-dose and standard-dose horse anti-thymocyte globulin in the treatment of severe aplastic anemia
Authors: Jain Arihant , Jandial Aditya , Mani Thenmozhi , Kishore Kamal , Singh Charanpreet , Lad Deepesh , Prakash Gaurav , Khadwal Alka , Das Reena , Varma Neelam , Varma Subhash , Malhotra Pankaj 
Published: February 2024

Abstract
Background
The standard dose (SD) of horse anti-thymocyte globulin (hATG) ATGAM (Pfizer, USA) or its biosimilar thymogam (Bharat Serum, India) for the treatment of Aplastic Anemia (AA) is 40 mg/kg/day for 4 days in combination with cyclosporine. Data on the impact of hATG dose on long-term outcomes are limited. Here, we describe our comparative experience using 25 mg/kg/day (low-dose [LD]) hATG for 4 days with SD for the treatment of AA.

Methods
We retrospectively studied patients with AA (age > 12 years) who received two doses of hATG combined with cyclosporine. Among 93 AA patients who received hATG, 62 (66.7%) and 31 (33.3%) patients received LD and SD hATG with cyclosporine, respectively. Among these,seventeen(18.2%) patients also received eltrombopag with hATG and cyclosporine. Overall response rates [complete response (CR) and partial response (PR)] of LD and SD hATG groups at 3 months (50% vs. 48.4%; p = 0.88), 6 months (63.8% vs. 71.4%; p = 0.67), and 12 months (69.6% vs. 79.2%; p = 0.167) were comparable. The mean (Standard Deviation) 5-year Kaplan–Meier estimate of overall survival and event-free survival was 82.1 (4.6)% and 70.9 (5.5)% for the study population. The mean (standard deviation) 5-year Kaplan–Meier estimate of overall survival and event-free survival of those who received LD hATG versus SD hATG dose was 82.9 (5·3)% versus 74.8 (10·3)% (P = 0·439), and 75.2 (6.2)% versus 61.4(11.2)% (P = 0·441).

Conclusion
Our study revealed that the response rates of patients with AA and LD were similar to those of patients with SD to hATG combined with cyclosporine in a real-world setting.
Developing a model for measuring fear of pain in Norwegian samples: The Fear of Pain Questionnaire Norway
Authors: Vambheim Sara M. , Lyby Peter Solvoll , Aslaksen Per M. , Flaten Magne Arve , Åsli Ole , Bjørkedal Espen , Martinussen Laila M. 
Published: February 2024

Abstract

Background
Fear of pain is highly correlated with pain report and physiological measures of arousal when pain is inflicted. The Fear of Pain Questionnaire III (FPQ-III) and The Fear of Pain Questionnaire Short Form (FPQ-SF) are self-report inventories developed for assessment of fear of pain (FOP). A previous study assessed the fit of the FPQ-III and the FPQ-SF in a Norwegian non-clinical sample and proved poor fit of both models. This inspired the idea of testing the possibility of a Norwegian FOP-model.

Aims and methods
A Norwegian FOP-model was examined by Exploratory Factor Analysis (EFA) in a sample of 1112 healthy volunteers. Then, the model fit of the FPQ-III, FPQ-SF and the Norwegian FOP-model (FPQ-NOR) were compared by Confirmatory Factor Analysis ( CFA). Sex neutrality was explored by examining model fit, validity and reliability of the 3 models amongst male and female subgroups.

Results
The EFA suggested either a 4-, a 5- or a 6-factor Norwegian FOP model. The eigenvalue criterion supported the suggested 6-factor model, which also explained most of the variance and was most interpretable. A CFA confirmed that the 6-factor model was better than the two 4- and 5-factor models. Furthermore, the CFA used to test the fit of the FPQ-NOR, the FPQ-III and the FPQ-SF showed that the FPQ-NOR had the best fit of the 3 models, both in the whole sample and in sex sub-groups.

Conclusions
A 6-factor model for explaining and measuring FOP in Norwegian samples was identified and termed the FPQ-NOR. This new model constituted six factors and 27 items, conceptualized as Minor, Severe, Injection, Fracture, Dental, and Cut Pain. The FPQ-NOR had the best fit overall and in male- and female subgroups, probably due to cross-cultural differences in FOP.

Implications
This study highlights the importance on exploratory analysis of FOP-instruments when applied to different countries or cultures. As the FPQ-III is widely used in both research and clinical settings, it is important to ensure that the models construct validity is high. Country specific validation of FOP in both clinical and non-clinical samples is recommended.
Eye movements as a tool to investigate exemplar retrieval in judgments
Authors: Rosner Agnes , Brändli Fabienne , von Helversen Bettina 
Published: February 2024

Abstract
The retrieval of past instances stored in memory can guide inferential choices and judgments. Yet, little process-level evidence exists that would allow a similar conclusion for preferential judgments. Recent research suggests that eye movements can trace information search in memory. During retrieval, people gaze at spatial locations associated with relevant information, even if the information is no longer present (the so-called ‘looking-at-nothing’ behavior). We examined eye movements based on the looking-at-nothing behavior to explore memory retrieval in inferential and preferential judgments. In Experiment 1, participants assessed their preference for smoothies with different ingredients, while the other half gauged another person’s preference. In Experiment 2, all participants made preferential judgments with or without instructions to respond as consistently as possible. People looked at exemplar locations in both inferential and preferential judgments, and both with and without consistency instructions. Eye movements to similar training exemplars predicted test judgments but not eye movements to dissimilar exemplars. These results suggest that people retrieve exemplar information in preferential judgments but that retrieval processes are not the sole determinant of judgments.
Average Jaccard index of random graphs
Authors: Feng Qunqiang , Guo Shuai , Hu Zhishui 
Published: February 2024

AbstractThe asymptotic behavior of the Jaccard index in G(n, p), the classical Erdös–Rényi random graph model, is studied as n goes to infinity. We first derive the asymptotic distribution of the Jaccard index of any pair of distinct vertices, as well as the first two moments of this index. Then the average of the Jaccard indices over all vertex pairs in G(n, p) is shown to be asymptotically normal under an additional mild condition that
$np\to\infty$
and
$n^2(1-p)\to\infty$
.
The Pleistocene ice-sheet dynamics in north-central Poland based on magnetic fabrics of tills and landform analysis
Authors: Teodorski Artur 
Published: February 2024

AbstractThis research was carried out in north-central Poland, which was occupied by the ice sheet of the Saalian (Marine Isotope Stage [MIS] 6) and Upper Stadial of the Weichselian (MIS 2) glaciation. The application of the anisotropy of magnetic susceptibility (AMS) method supported by a digital elevation model (DEM) analysis of the orientation of glacial landforms allowed for the reconstruction of ice-sheet extent and ice movement directions of these two Pleistocene glaciations. The research used an innovative method of collecting AMS till samples from the glacial plateau areas. Based on the research, it was found that during the general recession of the ice sheet of the Saalian glaciation, a previously undescribed glacial transgression occurred, characterized by a different direction of ice-sheet movement. On the basis of detailed geomorphological studies of the area of terminal moraines, previously described in fragments, the maximum extent of the ice sheet during the Weichselian glaciation was clarified. The recession of the ice sheet of the Weichselian glaciation from the area of north-central Poland took place in four regressive or transgressive–regressive stages with variable directions of ice-sheet movement. The results obtained indicate the great potential of the AMS method in paleoenvironmental studies of glaciated areas.
LEGAL DEATH AND ODYSSEUS’ KINGSHIP
Authors: Levin Itamar 
Published: February 2024

AbstractThe paper proposes a solution to the problem with Odysseus’ kingship in the Odyssey by maintaining that Odysseus is not officially considered dead. Consequently, Telemachus cannot inherit the position of king and Penelope must leave Odysseus’ household before remarrying. After discussing the modern concept of legal death and previous interpretations of the Ithacan situation, the paper focusses on Athena's speech at 1.275–92. A close reading demonstrates that erecting a cenotaph to Odysseus would be tantamount to a modern declaration of death in absentia, since it will render Penelope a widow and Telemachus the head of the household. This legal convention chimes with the Homeric depiction of Hades.
“Without Solidarity, No People”: International Solidarity in the East German People's Solidarity
Authors: Hachmeister Maren 
Published: February 2024

AbstractPeople's Solidarity (Volkssolidarität) is an East German organization founded in Dresden, Saxony, in 1945. It is primarily known for its activities dedicated to the care of older people. However, in the early 1950s, members of People's Solidarity were also involved in international solidarity campaigns for Greece, North Korea, and Vietnam. This article examines this little-known chapter of the organization's past. It reveals an unusual willingness among older East Germans both to donate money for the benefit of people in distant countries, and to relate to their suffering regardless of the (post-war) hardships faced at home. As the example of People's Solidarity shows, internationalism to some extent informed the roots of everyday, voluntary care practices under socialist rule in East Germany.
“Solidarity Is a Matter of the Heart”: Anti-Imperialist Solidarity Donations in GDR Children's Magazines
Authors: Dalljo Jessica 
Published: February 2024

AbstractThe article examines the role of children's magazines in promoting internationalism and solidarity in the German Democratic Republic (GDR). Analysing the magazines ABC-Zeitung, Bummi, and Frösi, it sheds light on their contribution to the GDR's system for collecting and distributing charitable donations and to cultivating children's commitment to countries in Africa, Asia, and Latin America. The article uncovers multifaceted layers of meaning associated with internationalism and emphasizes the significance of the connection between the state-ideological and the everyday levels. Its analysis of primary sources, including articles from the children's magazines, files from the Federal Archives, and historical publications, reveals that the magazines played a crucial role in fostering international solidarity and shaping the political consciousness of young readers. The use of techniques such as suggestion, competition, and renunciation in the magazines not only evoked a sense of collective responsibility, but also positioned children as active contributors to shaping an international socialist future. The children's magazine Bummi is particularly significant in the GDR's charitable donations system as it shows the involvement of other parts of society and thus raises issues of transgenerational education through the medium of children's magazines. By shifting away from the narrative of indoctrination, this article highlights the broader understanding of internationalism in the GDR and its integration into everyday life. It therefore underscores the vital role of children's magazines not only in fostering a stance of anti-imperialist solidarity among young readers, but also in shaping the GDR's vision of an international socialist future.
Solidarity and the Aesthetics of Pain: Soviet Documentary Film and the Vietnam War
Authors: Roth-Ey Kristin 
Published: February 2024

AbstractThe Soviet campaign in support of the Democratic Republic of Vietnam in the Vietnam War saturated Soviet public culture in the late 1960s and early 1970s. It was the longest solidarity action in Soviet history and the first to reach mass television audiences. This article examines the production and reception of a televised documentary film about the Vietnam War made by Konstantin Simonov – a celebrity writer who played a crucial role in Soviet culture during World War II, and then, in the post-war period, in the struggle to come to terms with terrible truths about Stalinism and the chaos and trauma that war had rendered. Simonov's film presented the Vietnam War in lyrical rather than analytical terms, calling upon viewers to draw connections between the suffering of the Vietnamese and the Soviet wartime experience and to enact their solidarity with the Vietnamese in terms of feeling. The film proposes a solidarity of pain and an understanding of war and wartime suffering as elemental and overwhelming. In dozens of letters to Simonov, we find an understanding and appreciation of this vision, which decentres Vietnam and instead sends viewers on a journey back to Soviet history and trauma.
Shedding and exclusion from childcare in children with Shiga toxin-producing Escherichia coli, 2018–2022
Authors: Vusirikala Amoolya , Rowell Sam , Dabke Girija , Fox Georgina , Bell Jade , Manuel Rohini , Jenkins Claire , Love Nicola , McCarthy Noel , Sumilo Dana , Balasegaram Sooria 
Published: February 2024

Abstract
Excluding children with Shiga toxin-producing Escherichia coli (STEC) from childcare until microbiologically clear of the pathogen, disrupts families, education, and earnings. Since PCR introduction, non-O157 STEC serotype detections in England have increased. We examined shedding duration by serotype and transmission risk, to guide exclusion advice. We investigated STEC cases aged <6 years, residing in England and attending childcare, with diarrhoea onset or sample date from 31 March 2018 to 30 March 2022. Duration of shedding was the interval between date of onset or date first positive specimen and earliest available negative specimen date. Transmission risk was estimated from proportions with secondary cases in settings attended by infectious cases. There were 367 cases (STEC O157 n = 243, 66.2%; STEC non-O157 n = 124, 33.8%). Median shedding duration was 32 days (IQR 20–44) with no significant difference between O157 and non-O157; 2% (n = 6) of cases shed for ≥100 days. Duration of shedding was reduced by 17% (95% CI 4–29) among cases reporting bloody diarrhoea. Sixteen settings underwent screening; four had secondary cases (close contacts’ secondary transmission rate = 13%). Shedding duration estimates were consistent with previous studies (median 31 days, IQR 17–41). Findings do not warrant guidance changes regarding exclusion and supervised return of prolonged shedders, despite serotype changes.
Steering signification for sustainability
Authors: Lahsen Myanna 
Published: February 2024

Abstract

Non-Technical Summary
Powerful influences on societal knowledge, values, and behavior, artificial intelligence-infused media systems, new and old, currently reinforce the interlinked problems of inequality and unsustainable consumption. This problem is rarely discussed in environmental research and policy, and even less so how it might be overcome. Discussing this consequential blind spot and the power structures that underpin it, this article argues that sustainability researchers should centrally explore the need and possibilities for democratic reconfiguration of the political economies and charters of media systems to achieve sustainability and other broad, inclusive public goals.

Technical Summary
Powerful influences on societal knowledge, values and behavior, artificial intelligence-infused media systems, new and old, currently tend to reinforce the interlinked problems of inequality and unsustainable consumption. This problem is rarely discussed in environmental research and policy, and even less so how it might be overcome. Discussing this consequential blind spot and the power structures that underpin it, this article argues that sustainability researchers should centrally explore the possibilities for democratic governance and reconfiguration of the political economies of media systems to foster human wellbeing and just transformations toward sustainability.

Social Media Summary
Sustainability transformations require ‘signification steering’ and interventions in media systems' configurations.
Exploring Observational Heliophysics Across All Scales: Reflections and Insights From the 2023 NASA Heliophysics Summer School
Authors: Shaver S. R. , Smith A. R. , Babu S. S. , Baruah Y. , Bauer M. , Chaturmutha V. , Chen H. , Dalal B. , Dias da Silva G. B. , Eddy T. , González G. , Gu S. , Gülay E. , Hoffmann A. P. , Idolor O. R. , Khan R. , Liou Y. , Liu N. , Lyu X. , Maharana A. , Radhakrishnan D. K. V. , Romeo O. M. , Silva P. O. C. , Salah H. M. , Thibeault C. , Weiss A. 
Published: February 2024

AbstractThe field of heliophysics encompasses a diverse range of research areas and rich plasma environments, from the solar dynamo and solar wind turbulence, to the complex terrestrial thermosphere‐ionosphere‐magnetosphere (TIM) system, to investigations of both induced and intrinsic magnetospheres across the solar system. This perspective paper delves into the experiences and outcomes of a summer school held in person in Boulder, Colorado, USA, from 7–11 August, which offered a platform for interdisciplinary learning and collaboration. The event, supported by NASA's Living with a Star program and hosted by the University Corporation for Atmospheric Research and Cooperative Programs for the Advancement of Earth System Science, assembled a cohort of 26 graduate students and postdoctoral researchers from around the world, all engaged in heliophysics research. The summer school included a series of lectures, interactive activities, and a culminating capstone project. The participants' diverse backgrounds enriched discussions and encouraged novel approaches to traditional problems. The capstone projects spanned an array of topics, including investigating the origins of solar wind switchbacks, dissecting the sequence of events from solar eruptions and their corresponding terrestrial consequences, investigating the energy transfer from solar coronal mass ejections to Earth's magnetosphere, and advocating for the exploration of Coulomb collisions in understanding large‐scale global systems. Through this perspective, we shed light on the value of international and interdisciplinary collaboration in advancing heliophysics research. This perspective paper encapsulates the ethos of the summer school, serving as a testament to the continuing and collective pursuit of unraveling the mysteries of the heliosphere.
Digital pathology-based artificial intelligence models for differential diagnosis and prognosis of sporadic odontogenic keratocysts
Authors: Cai Xinjia , Zhang Heyu , Wang Yanjin , Zhang Jianyun , Li Tiejun 
Published: February 2024

AbstractOdontogenic keratocyst (OKC) is a common jaw cyst with a high recurrence rate. OKC combined with basal cell carcinoma as well as skeletal and other developmental abnormalities is thought to be associated with Gorlin syndrome. Moreover, OKC needs to be differentiated from orthokeratinized odontogenic cyst and other jaw cysts. Because of the different prognosis, differential diagnosis of several cysts can contribute to clinical management. We collected 519 cases, comprising a total of 2 157 hematoxylin and eosin-stained images, to develop digital pathology-based artificial intelligence (AI) models for the diagnosis and prognosis of OKC. The Inception_v3 neural network was utilized to train and test models developed from patch-level images. Finally, whole slide image-level AI models were developed by integrating deep learning-generated pathology features with several machine learning algorithms. The AI models showed great performance in the diagnosis (AUC = 0.935, 95% CI: 0.898–0.973) and prognosis (AUC = 0.840, 95%CI: 0.751–0.930) of OKC. The advantages of multiple slides model for integrating of histopathological information are demonstrated through a comparison with the single slide model. Furthermore, the study investigates the correlation between AI features generated by deep learning and pathological findings, highlighting the interpretative potential of AI models in the pathology. Here, we have developed the robust diagnostic and prognostic models for OKC. The AI model that is based on digital pathology shows promise potential for applications in odontogenic diseases of the jaw.
Recent progress of CDK4/6 inhibitors’ current practice in breast cancer
Authors: Wang Xueqing , Zhao Shanshan , Xin Qinghan , Zhang Yunkun , Wang Kainan , Li Man 
Published: February 2024

AbstractDysregulated cellular proliferation represents a hallmark feature across all cancers. Aberrant activation of the cyclin-dependent kinase 4 and 6 (CDK4/6) pathway, independent of mitogenic signaling, engenders uncontrolled breast cancer cell proliferation. Consequently, the advent of CDK4/6 inhibition has constituted a pivotal milestone in the realm of targeted breast cancer therapy. The combination of CDK4/6 inhibitors (CDK4/6i) with endocrine therapy (ET) has emerged as the foremost therapeutic modality for patients afflicted with hormone receptor-positive (HR + )/HER2-negative (HER2-) advanced breast cancer. At present, the Food and Drug Administration (FDA) has sanctioned various CDK4/6i for employment as the primary treatment regimen in HR + /HER2- breast cancer. This therapeutic approach has demonstrated a substantial extension of progression-free survival (PFS), often amounting to several months, when administered alongside endocrine therapy. Within this comprehensive review, we systematically evaluate the utilization strategies of CDK4/6i across various subpopulations of breast cancer and explore potential therapeutic avenues following disease progression during application of CDK4/6i therapy.