bluuebunny/crossref_metadata_2025_split huggingface dataset:
Validity and Reliability of the Turkish Version of the Gastroesophageal Reflux Disease Quality of Life Questionnaire
Authors: Trabzon Şeyma , Sert Havva 
Published: March 2024

Objective: Gastroesophageal reflux is a disease that is common in society and affects quality of life. The aim of the present study was to test the validity and reliability of the Turkish version of the Gastroesophageal Reflux Disease Quality of Life scale.
Methods: A total of 161 patients with gastroesophageal reflux disease who applied to the gastroenterology outpatient department of a university hospital between July 2017 – October 2017 constituted the sample of this study. The study was a methodological and descriptive study. In the validity and reliability studies, the language validity, content validity, internal consistency (Cronbach’s alpha reliability coefficient) and confirmatory factor analysis methods were used.
Results: The Cronbach’s alpha reliability coefficient of the Gastroesophageal Reflux Disease Quality of Life scale was α = 0.885, while its content validity ranged between 0.84-0.92. According to confirmatory factor analysis, the 4-factor structure of the scale, consisting of 16 items, generally had good fit.
Conclusion: The Turkish version of the Gastroesophageal Reflux Disease Quality of Life scale was found to be a valid and reliable scale that can be used to measure the quality of life of individuals diagnosed with gastroesophageal reflux disease.
The Effect of Structured Education on Nurses’ Ventrogluteal Injection Knowledge and Skills
Authors: Kaynar Şimşek Aynur , Okuroğlu Gülten , Çaylı Nazan , Alpar Ecevit Şule 
Published: March 2024

Objective: For a safe intramuscular injection, it is essential to provide nurses with knowledge and skills for using the ventrogluteal site. This study was conducted to determine the effect of structured education on the knowledge and skills of nurses on ventrogluteal injection and their ventrogluteal site preference for intramuscular injection.
Methods: The study was carried out between February and December 2021. The sample consisted of 81 nurses. While training was given to the experimental group (n=46), no training was provided for the control group (n=35). The data were collected using the Information Form, Determination Form of First-Choice Site for Intramuscular Injection, Knowledge Level Form for Ventrogluteal Injection Administration,
Ventrogluteal Injection Skill Checklist, and Observation Form for Determining the Choice Site for Intramuscular Injection.
Results: The experimental group’s follow-up test rates of choosing the ventrogluteal site for intramuscular injection were found to be higher than those of the control group. Besides, In the follow-up data, the knowledge and skill scores of the experimental group for administering injections into the ventrogluteal site were found to be higher than those of the control group (p
The Effect of Music on Pregnancy Complaints with Sleep and Quality of Life in Risky Pregnant Women
Authors: Sabancı Baransel Esra , Uçar Tuba 
Published: March 2024

Objective: This study aimed to examine the effect of music therapy on pregnancy complaints and quality of sleep and life in risky pregnant women.
Methods: This is a prospective randomized controlled study. The sample of the study consisted of a total of 112 pregnant women who referred to a hospital in a city in Turkey for pregnancy follow-up (56 in the experimental group, 56 in the control group). Risky pregnant women in the experimental group were listened to music for four weeks before going to sleep, and those in the control group received no intervention. The data were collected between July and October 2022, using an introductory information form (IIF), a risk assessment form (RAF), the Assessment Scale for Pregnancy Complaints and Their Impact on Life Quality (ASPCILQ), and the Richard-Campbell Sleep Questionnaire (RCSQ).
Results: Risky pregnant women in the experimental group had higher ASPCILQ and RCSQ post-test mean scores than those in the control group, and the difference between them was statistically significant (p
A Scale Development Study: The Vitamin D Health Belief Scale According to The Health Belief Model
Authors: Kolaç Nurcan 
Published: March 2024

Objective: This study was conducted to develop Vitamin D Health Belief Scale based on the health belief model in adult women and determine its validity and reliability.
Methods: The sample of the study consisted of 404 women who were aged between 18 and 65, volunteered to participate in the study, and met study criteria. The theoretical framework of the scale was based on the health belief model. During the scale development stage, exploratory factor analysis and index values were evaluated by using confirmatory factor analysis, item-total correlation, and mean scores.
Results: The content validity index of the scale was found as 91.52%. As a result of the factor analysis, the variables were gathered under 6 factors with a total explained variance of 58.22%. Cronbach’s alpha value of the scale was determined as.884.
Conclusion: As a result of all analyses, a 5-point Likert-type scale that consisted of 31 items was developed. Six factors were obtained from the scale: perceived sensitivity, caring, health motivation, perceived benefits, perceived barriers, and self-efficacy. The total score of the scale gives the Vitamin D Health Belief score. The lowest and highest scores on the scale which consists of 31items are 31 and 155
respectively. It is recommended to use this scale to determine vitamin D health beliefs in adult women.
Presumptive Molecular Interconnections Between COVID-19 And Huntington’s Disease
Authors: Sarı Ak Duygu , Alomari Omar , Kılıç Ülkan 
Published: March 2024

Objective: The healthcare system worldwide has faced unparalleled challenges as a result of the coronavirus disease of 2019 (COVID-19) pandemic. While respiratory tract disease is the most common symptom of COVID-19, there is increasing evidence of neurological damage caused by the virus. To guide the clinical management of the disease, it is essential to elucidate the mechanisms underlying the
pathophysiology of COVID-19. Various research indicate that COVID-19 patients exhibit reduced levels of brain-derived neurotrophic factor (BDNF), which is also a hallmark of Huntington’s disease, a neurodegenerative disorder. The objective of this study is to investigate the possible links between COVID-19 and Huntington’s disease. This aim is motivated by the need to guide the clinical management of COVID-19, especially given the increasing evidence of neurological damage caused by the virus, including reduced levels of BDNF, a hallmark also observed in Huntington’s disease.
Methods: The comprehensive literature review conducted for both COVID-19 and Huntington’s disease, focusing on the genes associated with both conditions. These genes were then analyzed using the STRING database to determine protein-protein interactions, aiming to elucidate the mechanisms underlying the pathophysiology of COVID-19 and its potential connections to Huntington’s disease.
Results: The outcomes of the study indicate that there could be molecular-level interactions between COVID-19 and Huntington’s disease, based on the literature research and STRING database analysis. Although the primary mechanism behind these interactions is not yet fully understood, the hypothesis suggests that BDNF and its high-affinity receptor TrkB may play a crucial role. Additionally, the study highlights olfactory dysfunction as a common symptom of COVID-19, which is also linked with various neurodegenerative conditions, including Huntington’s disease.
Conclusion: This work emphasizes the connection between COVID-19 and neurodegenerative diseases, particularly through the lens of olfactory dysfunction, a common symptom shared by COVID-19 and Huntington’s disease. The potential molecular interactions observed suggest that COVID-19 could exacerbate neurodegenerative processes. This underscores the critical need for further research focused on olfactory dysfunction as a key symptom, to better understand and manage the implications of COVID-19 in patients with neurodegenerative conditions.
Evaluation of the Accessory Canals of Canalis Sinuosus Via Cone Beam CT
Authors: Türker Nurşat , Göller Bulut Duygu , Bayrak Seval 
Published: March 2024

Objective: Canalis sinuosus (CS) is a common anatomical variation in the anterior maxilla that originates from the infraorbital canal and carries the anterior superior alveolar nerve and vessels. This study aimed to examine the presence, frequency, and features of CS and its accessory canals (ACs) using cone beam computed tomography (CBCT) images.
Methods: A total of 495 CBCT images were retrospectively analyzed in axial, sagittal, and coronal sections. Patient age and sex, presence or absence of CS, location as right, left, or bilateral if CS was present, and number of ACs were recorded. In addition, the end regions of the ACs were recorded as central incisor, central-lateral incisor, lateral incisor, lateral incisor-canine, and canine regions. All recorded data were statistically analyzed.
Results: At least one CS was found in 54 (10.9%) of 495 CBCT images. CS(s) were bilateral in 26 (48.2%) cases and unilateral in 28 (51.8%; 25 on the left and 3 on the right side). The ACs of the CS predominantly terminated in the lateral incisor region (p =.025). The frequency of CS was not statistically different between males and females (p =.313).
Conclusion: Accessory canals in the anterior maxilla are mostly associated with branches of the CS. In the current study, the prevalence of CS was 10.9%, and most of the CSs were opening in the lateral incisor region. Detection of accessory canals in the anterior maxilla and examination of this region with CBCT will prevent misdiagnoses and postoperative complications arising from damage to these structures.
FIRST REPORT OF CURVULARIA LUNATA AND ALTERNARIA ALTERNATA CAUSING LEAF BLIGHTS ON TOMATOES IN SINDH, PAKISTAN
Authors: Magsi Qurban Ali , Saand Mumtaz Ali , Kalwar Muhammad Sajjad , Sahib Ghanghro Sahib Ghanghro , Shaikh Gul Hassan Shaikh , Soomro Shoukat Ali Soomro , Dharejo Ghulam Abid Dharejo , Pathan Maria Khan Pathan , Bhatti Ghulam Mustafa Bhatti , Koondhar Naimatullah 
Published: March 2024

The tomato is an economically important crop that grows worldwide. The numerous fungal pathogens attacking tomato crops and causing severe diseases lead to yield loss. A few studies conducted regarding the identification of tomato fungal pathogens in Pakistan. However, no report was found to identify the fungal pathogens of tomato crops grown in Sindh. This study aimed to isolate, identify and characterize the tomato fungal pathogens in District Kamber Shahdadkot. Subsequently, thirty diseased tomato plant samples (leaves & stems) were collected from distinct villages of Taluka Kamber District Kamber Shahdadkot. These samples were collected in polythene bags and marked with symbols like S1, S2 and so on (S=Sample). All samples were brought into Botany Department lab and CBC Shah Abdul Latif University Khairpur. PDA media was prepared, sterilized and poured into petri plates. Prior to the inoculation, pieces from samples were soaked in a 1% solution of sodium hypochlorite (NaOCl) for a minute. The petri plates were inoculated separately and incubated at natural room temperature (260C to 280C) for arising and growth. Three days later, the inoculation site manifests signs and symptoms of fungal development. Within a week fungus reached at preferable growth and spores were formed. Two slides from each petriplate were prepared i. e. one from the center of the cultures and other from the margins of the cultures. In order to finish this application, slide-sized scotch tape was cut up and immersed on the surface of cultures gently. The off cuts of the scotch tap introduced the fungal materials (mycelia and spores), which were pressed with love to the glass slides and observed. The fungi identification was made by using applications of morphological characteristics like morphology of the cultures, nature, and type of the mycelium, the shape of spores, and the color of the spores. Following these characters two fungal species were identified i. e. Curvularia lunata and Alternaria alternata
ANALYSIS OF HISTORICAL BUILDINGS OF THE BEGINNING OF THE XX CENTURY WITH CLOSED YARD SPACES IN THE CITY OF TAMBOV
Authors: Petuhova N. , Zhorkina D. 
Published: March 2024

This article describes the process of forming a new element of the urban planning structure, the closed courtyard, which was formed in the late 19th – early 20th century. To study this topic, an analysis is made of three historical buildings with closed courtyard spaces located in the city of Tambov, among them:
V.V. Galkin's apartment house, M. V. Aseev's apartment house and K. I. Turchaninov's apartment house.
The article also proves the similarity of their configurations with the tenement houses of St. Petersburg: the tenement house of F. I. Lidval, the tenement house of G. G. von Goli and the tenement house of A. N. Pertsov, built in the same time period, the reasons and prerequisites are revealed for the formation of courtyard spaces of a single type in the late 19th - early 20th century.
In addition, the article raises the question of the need to introduce a complex of buildings for the profitable house of M. V. Aseev, located at Tambov, st. M. Gorky, 49, in the register of OKN. As evidence of the need to include objects in the register, the value characteristics of the ensemble of the profitable house of M. V. Aseev are described.
Efeitos do uso de dexmedetomidina na sedação paliativa de pacientes em fim de vida: revisão sistemática
Authors: Dos Santos Davi Silva , De Oliveira Nádia Marisa Sotério 
Published: March 2024

Objetivo: Revisar na literatura os efeitos do uso de dexemedetomedina para sedação paliativa de pacientes em fim de vida. Método: Trata-se de uma revisão sistemática, sendo que este estudo adotou os critérios do Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA). Uma busca sistemática foi realizada nas seguintes bases de dados: Medical Literature Analysis and Retrieval System Online (Medline/Pubmed) e a Literatura Latino-Americana e do Caribe em Ciências da Saúde (LILACS). Resultados: A partir do aspecto de elegibilidade para a revisão, foram selecionados e apresentados 8 artigos. Conclusão: De acordo com os estudos pesquisados, a dexmedetomidina como agente sedativo induz um estado semelhante ao sono, permitindo um despertar rápido, além de fornecer analgesia, alívio da ansiedade e diminuição do delirium. Portanto, é uma opção eficaz na sedação paliativa de pacientes em fim de vida, principalmente se o cuidado padrão não foi eficaz.
Efeitos in vitro da terapia fotodinâmica e fotossensibilizador (azul de metileno) em Stenotrophomonas maltophilia
Authors: Davoglio Larissa Maria de Paula , Costa Matheus Medeiros , Federisi Alexandre , Da Silva Amanda Cristina , Garcia Ana Laura Folcheti , Bittencourt Camila Borges , Dias Claudia Rodrigues Mustafa , Turco Débora Constant , Pereira Eduarda Franco Peres , Zamparo Isadora Romanha , Garcia João Neto , Rebischke Julia Giovanetti , Martins Luisa Longhini , Cuani Shyara , Navarro Victor Martins , Santos Kayane Silva 
Published: March 2024

Infecções relacionadas a cuidados de saúde apresentam-se como problemática constante para a saúde publica mundial. Os aumentos de morbimortalidade, tempo de internação e custos hospitalares, são impactos causados pela crescente prevalência de microrganismos resistentes a antimicrobianos. A Stenotrophomonas maltophilia, por possuir resistência bacteriana intrínseca a antibióticos habitualmente utilizados, tem se mostrado como importante causadora de graves infecções hospitalares. Nesse contexto, a utilização de terapia fotodinâmica (TFD), caracterizada pela utilização de um agente fotossensibilizador e fonte de luz específica, com intuito de gerar espécies reativas de oxigênios no meio inserido, tem se mostrado eficaz como alternativa antimicrobiana no controle de crescimento de bactérias encontradas em ambiente nosocomial. Objetivou-se, através da análise in vitro de S. maltophilia, o impacto de tal terapia sob culturas, sendo comparadas a grupo controle, exposição ao fotossensibilizador e apenas à fonte de luz. Variou-se em relação a tempo de exposição com manutenção de energia e comprimento de onda utilizado. Evidenciou-se controle eficaz de replicação bacteriana além de efeito bactericida expressivo, com redução em cerca de 90% da quantidade de unidades formadoras de colônias (UFC), principalmente quando comparados ao grupo controle. Além disso, foi evidenciado o aumento em UFC’s quando expostas apenas à luz, estimulando o processo enzimático, demonstrando a necessidade da utilização de fotossensibilizador como substância produtora de moléculas instáveis responsáveis por efeito antimicrobiano. Assim, a partir dos resultados obtidos in vitro associados a propriedades físico-quimicas, manejo e disponibilidade, a utilização da TFD como agente antimicrobiano tem ganhado cada vez mais importância e relevância clínica.
Um estudo descritivo do COVID-19 no estado de São Paulo
Authors: De Castro Carolina Durães , Longo Juliano Peixe , Da Silva José Adair 
Published: March 2024

A pandemia do COVID-19 impôs uma mudança extrema na rotina da população e adequações foram necessárias em todos os cenários cotidianos e principalmente nos serviços de saúde. É particularmente importante o acompanhamento do espalhamento da doença no estado de São Paulo, o mais populoso estado brasileiro, com 44,3 milhões de habitantes e intenso fluxo de pessoas em rotas nacionais e internacionais. Trata-se de um estudo descritivo realizado com dados da Unidade Federativa (UF) de São Paulo, no período compreendido entre a ocorrência do primeiro caso confirmado de COVID-19 no país, dia 26 de feve­reiro de 2020, até o dia 30 de junho de 2022. Os números de casos confirmados e óbitos por COVID-19 notificados aos sistemas de vigilância epidemiológica de cada UF de acordo com a padronização nacional e estadual, ocorridos durante o período do estudo em cada UF, foram obtidos por meio da plataforma Brasil.io (https://brasil.io/covid19/), que coleta e revisa diariamente os dados publicados, tornando-os mais acurados e atualiza­dos. Esse site utiliza como fonte os dados oficiais reportados pelos boletins e informes epidemiológi­cos das Secretarias Estaduais de Saúde das 27 UF. A COVID-19 atingiu de forma súbita e poderosa o mundo. Conforme ela foi atingindo mais e mais pessoas, ficou claro que seriam necessárias intervenções rápidas para frear o seu avanço. O estado de São Paulo é um dos mais populosos do Brasil e sentiu o impacto da pandemia no seu cotidiano, afetando os aspectos econômicos, sociais e culturais do Estado. Os dados epidemiológicos fornecidos pelo Sistema Estadual de Análises de Dados (SEADE-SP) demonstram que a pandemia ainda é uma realidade presente no cotidiano dos paulistanos. Os números apontam que mais de 5.000.000 foram notificados até julho de 2022 e que a cidade de São Paulo é a cidade com o maior número de notificações do Estado. Porém, questiona-se se esses números não são subestimados e quantas não notificações foram deixadas de fora. Espera-se que o presente trabalho auxilie os profissionais a criarem estratégias de enfrentamento e que em breve, o COVID-19 seja uma triste lembrança na linha do tempo mundial.
A importância da saúde do trabalhador na atenção básica
Authors: Do Nascimento Marcela Melo , Da Silva Júnior Valdir Barbosa 
Published: March 2024

Introdução: A saúde do trabalhador se configura como um pilar fundamental no contexto da atenção básica, desempenhando um papel essencial na construção de uma sociedade mais saudável e equitativa. Objetivo: Aprofundar a compreensão acerca da interrelação entre a saúde do trabalhador e a atenção básica em saúde, explorando as nuances dessa conexão vital. Métodos: Trata-se de uma revisão integrativa da literatura. Adotou-se como pergunta norteadora: "Como a atenção básica pode promover e garantir a saúde dos trabalhadores?" Para construção da pesquisa, a coleta e análise de dados foi realizada através do Portal da Biblioteca Virtual em Saúde e das bases de dados Medical Literature Analysis and Retrievel System Online via PubMed e Google Acadêmico através dos seguintes Descritores em Ciências da Saúde (DeCS): “Vigilância em Saúde do Trabalhador”, “Atenção Primária à Saúde”, “Promoção da Saúde” combinados entre si pelo operador booleano AND com seus respectivos correspondentes no Mesh Terms. Resultados e Discussão: Após o cumprimento dos procedimentos metodológicos, 12 artigos disponíveis no Portal da BVS, na base de dados PubMed e no Google Acadêmico foram selecionados, os quais retratam que a saúde do trabalhador é um tema de extrema importância na atenção básica, pois influencia diretamente a qualidade de vida e o bem-estar da população. Considerações Finais: A saúde do trabalhador é um tema de extrema importância na atenção básica, pois impacta diretamente a qualidade de vida e produtividade dos indivíduos. A atenção básica desempenha um papel fundamental na promoção da saúde do trabalhador.
Perfil epidemiológico dos casos de tuberculose no município de Maceió, nos anos de 2018 a 2022
Authors: Lima Maria Eduarda Maia Torres , Calheiros Kalinne Serejo Medeiros Pinaud , Lopes Lailda Maria Sarmento , Araújo Ellen Bastos Tenorio de , Melo Vinícius Couto de Albuquerque , Calheiros Karolinne Serejo Medeiros Pinaud , Lopes Isabelli Maria Sarmento , Sampaio Maria Fernanda Calheiros Magalhães 
Published: March 2024

Objetivo: Avaliar o perfil epidemiológico perfil dos casos de tuberculose em Maceió durante o período de 2018 a 2022. Métodos: Trata-se de um estudo epidemiológico retrospectivo, de caráter descritivo e abordagem quantitativa dos casos notificados no município de Maceió, no período de 2018 a 2022, coletados no Sistema de Informação de Agravos de Notificação (SINAN). Resultados: Em relação ao perfil a maioria possui de 20 a 39 anos, com baixa escolaridade, do sexo masculino. A apresentação clínica foi a Tuberculose pulmonar com 67,87%. Conclusão: Os elementos socioeconômicos estão associados aos registros de tuberculose, incluindo habitações precárias e falta de saneamento básico. Além disso, observa-se uma maior incidência em pessoas com condições sociais desfavorecidas, que frequentemente enfrentam carências alimentares. Esses dados evidenciam a relevância desse aspecto na implementação de medidas preventivas e na redução dos casos no âmbito estadual. Um desafio para a saúde pública foi evidenciada neste estudo, revelando um crescimento contínuo ao longo dos anos.