bluuebunny/crossref_metadata_2025_split huggingface dataset:
The effect of collagen matrix graft on palatal fistula formation after cleft palate repair: A preliminary randomized controlled study
Authors: Egbunah Uchenna Patrick , Zhu Yaner Tracy , Hauri Dimitri D. , Ratz Tiara , Thor Andreas Lennart Ivan 
Published: April 2024

ABSTRACT

Objective:
The objective of this study was to compare the incidence of palatal fistula formation between cleft palate (CP) repair with collagen matrix graft and conventional repair without collagen matrix graft.

Patients and Methods:
This was a preliminary randomized controlled study of patients with CP who underwent primary palatoplasty (two-flap palatoplasty technique) at the Lagos University Teaching Hospital. Patients were randomly allocated to either the test group (palatoplasty with collagen graft) or the control group (palatoplasty without collagen graft). The primary outcome was palatal fistula, and secondary outcomes were wound dehiscence, surgical site inflammation, surgical site infection, and surgeon satisfaction up to 3 months postoperative (PO).

Results:
Ten patients were recruited, five in each group. Only one patient in the control group developed a palatal fistula at 1 month PO on the soft palate which extended to the junction of hard and soft palate at 3 months PO. Eight patients developed wound dehiscence, five in the test group and three in the control group. Surgical site inflammation persisted up to at least 7 days PO in nine patients (five in the test group and four in the control group). All persistent wound dehiscence and surgical site inflammation resolved at 3 months PO. No patient developed surgical site infection. No significant difference was seen between the study group and wound dehiscence, surgery time, and difficulty of the procedure (P > 0.05 for all associations).

Conclusion:
Collagen graft may have a protective effect against fistula formation without significantly increasing surgery time and difficulty. However, due to the small sample size, the study failed to draw definite conclusions. Results from this study may inform future designs of larger randomized controlled studies.
A novel technique myomucosal rotational upper lip flap for anterior palatal fistula closure
Authors: Solano Nicolas , Carcelén Francisco , Oropeza Rafael , López Patricia 
Published: April 2024

ABSTRACT
Palatal fistulas are a pathological condition where there is a connection between the nasal area and the oral cavity, being one of the most frequent complications in cleft palate surgery. Palatal fistulas can cause esthetic defects and functional alterations in both feeding and speech of patients. Anterior palatal fistulas are the least common but represent a great surgical challenge for the surgeon because of their location and poor amount of tissue for closure. The purpose of this article is to present a novel technique of performing an upper lip myomucosal rotation flap for the closure of an anterior fistula, taking advantage of the labial tissue for a tension-free suture in the area of the fistula. Our technique allowed an adequate management of the fistula with low morbidity and without flap necrosis, proposing it as a useful technique for the closure of anterior fistulas.
Thurston syndrome in two Indian female siblings
Authors: Samuel Samson , Parab Shrikrishna , Sharma Sunil , Kumar Chandan 
Published: April 2024

ABSTRACT
Thurston syndrome (oral-facial-digital syndromes [OFDS] Type V) is characterized by median cleft lip, postaxial polydactyly of hands and feet, and other oral manifestations. It is one of the OFDS described earlier in the literature. It is commonly seen in individuals of Indian origin and has autosomal recessive inheritance. This article presents two Indian female siblings with median upper lip cleft associated with postaxial hexadactyly of both hands. Rarely have such cases been reported by any author. Majority of the previously reported cases are males. This is the first case report of female siblings with Thurston syndrome.
Prevalence of gestational diabetes mellitus, fetal and maternal outcomes of parturients with risk factors versus parturients without risk factors for gestational diabetes mellitus: A preliminary analysis of the comparative study of blood sugar levels at a
Authors: Omo-Aghoja L.O. , Onohwakpor E.A. , Adeyinka A.T. , Asaboro N. , Lucky Oyeye 
Published: April 2024

Background: Typically asymptomatic, gestational diabetes mellitus (GDM) has been associated with myriads of maternal and fetal complications and has been shown to predict morbidity in both mother and the newborn much later in life. The incidence of these complications in GDM has been strongly associated with a maternal glycemic level. As a generalization, the degree of maternal hyperglycemia dictates the fetal outcome.
Methods: This study was a prospective cohort analytical observational study of blood glucose levels amongst two cohorts of women who attended antenatal care at the obstetric unit of Delta State University Teaching Hospital, Oghara.
Results: The prevalence of GDM was 31.3% and 9.4%, respectively, for cases and controls. The difference in prevalence and glycemic control was statistically significant. The subjects were recruited based on a positive history of - previously haven had macrosomic babies, maternal weight greater than 90kg, unexplained intrauterine fetal death/stillbirth, fasting glycosuria, and the presence of a family history of GDM in first-degree relatives. Interventional deliveries and maternal and fetal complications were statistically significantly higher in cases than in controls.
Discussion: The prevalence of GDM in cases was significantly higher than in the controls; this seems to have given some credence to the fact that the risk factors based on which the patients were recruited may indeed be predictive of the risk of developing GDM in the pregnant parturients in Delta State Nigeria.
Clinical attributes, histopathological characteristics and surgical outcomes of endometrial cancers at the University of Benin Teaching Hospital in Nigeria
Authors: Ezeanochie M.C. , Nweke V.C. , Isikhuemen Me , Okonkwo C.A. 
Published: April 2024

Introduction: Endometrial cancer is probably the third commonest gynaecological cancer in sub-Saharan Africa. It occurs more commonly in the post-menopausal women. This research aims to document the clinical profile, histopathological types and survival rate of endometrial cancer patients with a view to improving care in our setting.
Materials and methods: This was a retrospective descriptive study of women with endometrial cancer who had surgery from January 1, 2013 to December 31, 2017. Case notes of patients satisfying the inclusion criteria were retrieved and relevant information extracted. The statistical analysis were done using Statistical Package for Social Sciences(SPSS) version 22.
Results: Thirty-three cases of endometrial cancer patients were reviewed. The mean age at presentation was 54.3+8years About half of the patients (45.5%) were hypertensive while 21.2% were diabetic. Twenty nine (87.9%) patients presented with abnormal uterine bleeding. All patients had total abdominal hysterectomy with bilateral salpingo-oophorectomy (TAH+BSO). Endometrial adenocarcinoma accounted for the majority of the histopathological type. One year survival following surgery was 97%.
Conclusion: When performed for early stage Endometrial cancer, TAH+BSO is associated with a favourable 1 year survival.
Использование курса «Digital art» в современной
профессиональной подготовке дизайнеров
Authors: Яковлева Светлана Игоревна , Чеберева Ольга Николаевна 
Published: April 2024

Рассмотрены понятия «цифровое искусство» и «Digital Art» как вида изобразительного искус-ства. Отличие Digital Art от других направлений современного искусства, его роль в современ-ном мире и тенденции развития. Актуализируется необходимость использования данного курса в современной профессиональной подготовке дизайнеров.
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YANGI O’ZBEKISTON VA IJTIMOIY DAVLATCHILIK
Authors: Quramboyev Alisher 
Published: April 2024

Davlatimiz tabiati tobora ijtimoiy mazmun kasb etib, o’z faoliyat mazmuniga ko’ra, demokratik, huquqiy, ijtimoiy va dunyoviy davlat sari odimlab bormoqda. Maqolada ushbu fikrlarning dalili o’laroq faktlar keltiriladi. Shuningdek, ushbu maqolada ijtimoiy davlat konsepsiyasining mazmun-mohiyati ochib beriladi. Yangilanayotgan O’zbekiston sharoitida ijtimoiy sohada amalga oshirilib kelinayotgan islohotlar, ayniqsa kam ta’minlangan oilalarni ijtimoiy muhofaza qilish haqida fikr yuritiladi. Shuningdek, jamiyat a’zolarini ijtimoiy muhofaza qilish, mamlakatda barqarorlikni ta’minlash, inson qadrini ulug’lash borasida olib borilayotgan say - harakatlarga doir fikr-mulohazalar berilgan.
ВОПРОСЫ СОВЕРШЕНСТВОВАНИЯ МЕЖДУНАРОДНЫХ СТАНДАРТОВ ТРАНСПАРЕНТНОСТИ ПРЕДСТАВИТЕЛЬНЫХ ОРГАНОВ МЕСТНОЙ ВЛАСТИ
Authors: Куатбек Гулнар 
Published: April 2024

В статье проведен анализ международных стандартов транспарентности представительных органов местной власти, вопросов их реализации в Узбекистане и Казахстане. В результате исследования было выявлено наличие множества источников международных стандартов транспарентности представительных органов местной власти, отсутствие среди них стандартов определения публичной информации, проведения открытых заседаний размещения ими информации в общедоступные места и некоторых способов раскрытия информации. Автор предложил унифицировать стандарты, отсутствующие восполнить стандартами транспарентности парламента, в частности дал определение открытому заседанию представительного органа местной власти.
MILLIY KURASH SPORT TURINING FUNKSIYALARI VA MAQSADGA ERISHISHDAGI VOSITALARI
Authors: Ustaev Abdurazzoq 
Published: April 2024

Ushbu maqolada muallif tomonidan xozirgi kunda milliy sport turi hisoblanmish kurashning funksiyalari va vositalari haqida fiklar yuritilgan. Kurashning millatimiz uchun o’rni va ahamiyati shuningdek, u bilan shug’ullangan sportchining yuqori natijalarga erishishi aytib o’tilgan. Milliy kurashdagi sport mashg‘uloti vositalari yani tabiatning tabiiy kuchlari, gigiyenik omillar, jismoniy mashqlarning tasnifi ochib berilgan.
Cultivating Community Health and Well-being in Open Source: Mitigating Burnout and Prioritizing Mental Health
Authors: Raghunathan Savitha 
Published: April 2024

Purpose: This whitepaper addresses the critical but often overlooked mental health challenges within open-source communities, including stress and burnout. The collaborative spirit of open-source communities has undoubtedly accelerated technological innovation, but the mental well-being of their contributors is frequently neglected. The objective is to uncover the root causes of these mental health issues and evaluate their impact, thereby underscoring the need for supportive and inclusive community practices.
Methodology: This paper uses the ‘Mixed methods’ research approach, analyzing data from industry surveys and extracting insights from personal narratives and experiences documented by contributors in blogs and forums. This comprehensive strategy allows for a detailed exploration of mental health within the open-source environment, facilitating the identification of key stress factors and mental health challenges associated with community participation.
Findings: The investigation reveals a direct link between the operational dynamics of open-source projects and the prevalence of mental health problems among participants. Key stressors include high expectations regarding workload, the predominantly volunteer nature of contributions, social isolation, and a lack of formal support structures. Additionally, the study highlights a significant lack of awareness of these issues and the availability of intervention strategies, further increasing the risk of burnout and stress among community members.
Unique Contribution to Theory, Practice, and Policy: This paper makes a novel contribution to understanding mental health in open-source communities by merging analytical data with qualitative insights from contributor narratives. It offers recommendations for a wide range of stakeholders, from contributors to leaders and policymakers, to cultivate a culture that supports mental well-being, diversity, and sustainability. This paper presents a comprehensive blueprint for nurturing healthier, more resilient open-source communities.
Calaspargase Pegol (Asparlas)
Authors: CADTH  
Published: April 2024

CADTH reimbursement reviews are comprehensive assessments of the clinical effectiveness and cost-effectiveness, as well as patient and clinician perspectives, of a drug or drug class.
The assessments inform non-binding recommendations that help guide the reimbursement decisions of Canada's federal, provincial, and territorial governments, with the exception of Quebec.
This review assesses calaspargase pegol (Asparlas), 3,750 units/5 mL (750 units/mL), concentrate for solution for IV infusion
Indication : As a component of a multiagent chemotherapeutic regimen for the treatment of acute lymphoblastic leukemia (ALL) in pediatric and young adult patients aged 1 year to 21 years
Qualitative indicator of foreign adapted potato varieties under the influence of fertilizers in the conditions of southeastern Kazakhstan
Authors: Alimkhanov Y. M. , Aitbaeva A. T. 
Published: April 2024

This paper presents the results of field experiments to study the effect of fertilizers on the quality of potato tubers of the Tien Shan, Gala, Alladin and Innovator varieties grown in the foothill zone of south-east Kazakhstan. The novelty of the research lies in the fact that for the first time in Kazakhstan she is studying the effect of fertilizers on the quality of potato tubers of four varieties grown in the foothill zone of the south-east of the country. The results obtained can be used to develop recommendations for the use of fertilizers for potatoes in this region. The results of the study are consistent with data from similar studies conducted in other regions of Kazakhstan and other countries. It has been established that the application of fertilizers helps to increase the content of dry matter, starch and total sugar in potato tubers. At the same time, the greatest starchiness of the tubers was noted when applying increased doses of mineral fertilizers or the combined use of mineral and organic fertilizers. The nitrate content in potato tubers of the Tien Shan, Gala and Aladdin varieties did not exceed the maximum permissible concentration (MPC - 250 mg/kg). In the tubers of the Innovator variety, the nitrate content was below the maximum permissible concentration, even in the control. Fertilizer application is an effective way to improve the quality of potato crops.
MIXv2: a long-term mosaic emission inventory for Asia (2010–2017)
Authors: Li Meng , Kurokawa Junichi , Zhang Qiang , Woo Jung-Hun , Morikawa Tazuko , Chatani Satoru , Lu Zifeng , Song Yu , Geng Guannan , Hu Hanwen , Kim Jinseok , Cooper Owen R. , McDonald Brian C. 
Published: April 2024

Abstract. The MIXv2 Asian emission inventory is developed under the framework of the Model Inter-Comparison Study for Asia (MICS-Asia) Phase IV and produced from a mosaic of up-to-date regional emission inventories. We estimated the emissions for anthropogenic and biomass burning sources covering 23 countries and regions in East, Southeast and South Asia and aggregated emissions to a uniform spatial and temporal resolution for seven sectors: power, industry, residential, transportation, agriculture, open biomass burning and shipping. Compared to MIXv1, we extended the dataset to 2010–2017, included emissions of open biomass burning and shipping, and provided model-ready emissions of SAPRC99, SAPRC07, and CB05. A series of unit-based point source information was incorporated covering power plants in China and India. A consistent speciation framework for non-methane volatile organic compounds (NMVOCs) was applied to develop emissions by three chemical mechanisms. The total Asian emissions for anthropogenic/open biomass sectors in 2017 are estimated as follows: 41.6/1.1 Tg NOx, 33.2/0.1 Tg SO2, 258.2/20.6 Tg CO, 61.8/8.2 Tg NMVOC, 28.3/0.3 Tg NH3, 24.0/2.6 Tg PM10, 16.7/2.0 Tg PM2.5, 2.7/0.1 Tg BC (black carbon), 5.3/0.9 Tg OC (organic carbon), and 18.0/0.4 Pg CO2. The contributions of India and Southeast Asia were emerging in Asia during 2010–2017, especially for SO2, NH3 and particulate matter. Gridded emissions at a spatial resolution of 0.1° with monthly variations are now publicly available. This updated long-term emission mosaic inventory is ready to facilitate air quality and climate model simulations, as well as policymaking and associated analyses.
Surface rupture kinematics of the 2020 Mw 6.6 Masbate (Philippines) earthquake determined from optical and radar data
Authors: Sta. Rita Khelly Shan , Valkaniotis Sotiris , Lagmay Alfredo Mahar Francisco 
Published: April 2024

Abstract. Optical correlation, interferometry, and field investigation of laterally offset features were undertaken to analyze the kinematics of the 2020 Mw 6.6 Masbate earthquake. Ground displacement fields show a peak left-lateral offset of 0.6 m corresponding to Mw 6.6 geodetic moment magnitude, with an average 0.4 m left-lateral slip. The slip distributions also indicate a single asperity located ∼200 m SE of the centroid. Post-seismic deformation estimates from interferometry highlight an at least 0.14 m left-lateral offset consistent with a Mw 6.2 post-seismic moment magnitude. The total and post-seismic slip distributions coincide with each other, with both peaks adjacent to the centroid. Slip measurements and the ∼28.2–41 km rupture length estimates from field and remote sensing datasets characterize the Masbate segment as capable of producing long ruptures with significant offsets despite the presence of interseismic creep. Post-seismic interferograms resolved the rupture far better than optical correlation, which was degraded due to high-amplitude noise from sensor and environmental sources. Nevertheless, this review of the 2020 Mw 6.6 Masbate earthquake provides a comprehensive slip measurement of the surface rupture and demonstrates the presence of two transtensional basins in the Masbate province, revealing new insights into the seismic hazard and seismotectonic setting of the central Philippines.
Etat de contrôle administratif sur la qualité des produits aurifères exportés par Madagascar : cadre legislatif malgache et norme internationale
Authors: RAMEFIVOLOLONA Hanitra Lalaina 
Published: April 2024

De nombreux États cherchent le moyen de renforcer leurs capacités d’évaluation des exportations de minéraux. Madagascar est conscient de la nécessité d’acquérir des connaissances et des compétences pour contrôler la qualité de minéraux et de métaux précieux comme l’or de façon efficiente et en temps opportun.A Madagascar, l’or commercialisé est supérieur ou égal à la pureté 18 Karat (Kt). Ce seuil constitue la base de calcul des frais retenus par l’administration. Alors que, d’après le régime de l’or, l’exportation de l’or ne peut se faire qu’à 24Kt de pureté. L’or exporté de Madagascar doit être considéré en quantité qu’en qualité pour contribuer davantage à la caisse de l’Etat.L’objectif de cet article est d’analyser le contrôle administratif sur la qualité des produits aurifères exportés de Madagascar par la méthode d’évaluation du guide IGF-OCDE afin de déterminer la conformité du système de contrôle administratif existant par rapport au cadre législatif Malgache et la norme internationale.Les résultats ont conclu que le contrôle administratif actuel sur la qualité de produit aurifère exporté de Madagascar présente un risque de sous-évaluation de produit, un risque de perte de redevances et ristournes minières (RRM) élevées causé par le point et le processus de contrôle ainsi qu’un risque de non fiabilité des résultats d’analyse sans un laboratoire accrédité et normalisé au niveau national et international.
Kinshasa Spoken Lingala As A Mixed Language
Authors: MUTSHOS AW’N Emile NSAKWEN 
Published: April 2024

Toute langue, en contact avec une ou plusieurs autres langues, subit des modifications en son sein et devient souvent une langue mixte. Le Lingala, parlée à Kinshasa, la capitale de la République Démocratique du Congo, est parmi les langues en situation de contact avec d’autres, de ce fait ; elle subit des changements par le mélange des mots provenant des autres langues avec lesquelles elle est en contact et devient par là une langue mixte.
Modeling Extreme Floods Susceptibility Using The Generalized Extreme Value Distribution: Case Study Of Gonse And Wayen, Burkina Faso.
Authors: Bontogho Patricia Emma Tog-Noma , Tockville Maré Boussa , Charlène Gaba Olayemi Ursula , Eliézer Biao Iboukoun 
Published: April 2024

Over recentes decades, Burkina Faso has experienced extremes events such as droughts and floods. In this study, flood frequency has been ascertained based on Generalized Extreme Value (GEV). To this end, discharge data from Gonse and Wayen stations are collected from the National Center for Water resources. The period of analysis goes from 1980 to 2022. The Kolmogorov-Smirnov test is applied to check the distribution of the time series. Then, the Maximum Likelihood Estimation (MLE) method is implemented to estimate the location, the scale and the shape parameters of the GEV distribution. The goodness-of-fit between the empirical data and the theorical distribution is then evaluated based on Akaike criterion (AIC) and Bayenan criterion (BIC). The results revealed that across Gonse station, the probability that the annual maximun discharge will be less than 30m3/s is 0.7 and the 50-year return period discharge is 37.33 m3/s. In Wayen station, the probability that the annual maximun discharge will be less than 200m3/s is 0.5 and the 50-year return period discharge is 226.38m3/s. The AIC is 308.10 and 484.61 respectively for Gonse and Wayen station. The BIC is 313.65 and 490.16 respectively for Gonse and Wayen station. The findings may provide a scientific base for managing the risks of floods to advance climate change adaptation over the Nakambe watershed.
PENERAPAN METODE FIELD VISIT UNTUK PENINGKATAN PRESTASI BELAJAR ADAPTASI MAKHLUK HIDUP PADA PELAJARAN IPS DI KELAS IX-A SMPN 2 KUTOREJO
Authors: Sugiamah Sugiamah 
Published: April 2024

Pembelajaran IPA di kelas IX-A SMP Negeri 2 Kutorejo Mojokerto tahun pelajaran 2021/2022, banyak mengalami kendala yang sangat krusial. Pada ulangan harian tentang adaptasi makhluk hidup, nilai rata–rata kelas yang didapat hanya sebesar 54,5 dan ketuntasan belajar secara klasikal mencapai 41,9%. Hal ini menunjukkan bahwa ada 13 siswa dari 31 siswa sudah tuntas belajar. Pembelajaran belum mencapai ketuntasan klasikal, karena siswa yang memperoleh nilai ³ 70 hanya sebesar 41,9% lebih kecil dari persentase ketuntasan yang dikehendaki sebesar 85%. Maka perlu diterapkan metode field visit. Jenis penelitian yang dilakukan oleh peneliti adalah penelitian tindakan (action research) karena penelitian dilakukan untuk memecahkan masalah pembelajaran di kelas. Penelitian dilaksanakan tanggal 5 Oktober 2022 sampai 15 Desember 2022. Berdasarkan penelitian yang telah dilakukan, maka diperoleh simpulan bahwa penerapan metode field visit dapat meningkatkan hasil belajar IPA tentang adaptasi makhluk hidup. Penerapan metode field visit pelajaran IPA tentang adaptasi makhluk hidup, dimulai dengan memberi tugas kepada setiap kelompok untuk mendiskusikan pengelompokan hewan dan tumbuhan yang ditemui selama perjalanan berdasarkan persamaannya bentuk fisiknya. Selanjutnya menghubungkan adaptasi makhluk hidup melalui adaptasi, seleksi alam, dan perkembangbiakan Pada siklus selanjutnya, siswa diberi tugas mendiskripsikan ciri-ciri mahluk hidup berikut hubungan antara ciri-ciri makhluk hidup dengan lingkungan tempat hidupnya.