bluuebunny/crossref_metadata_2025_split huggingface dataset:
A qualitative exploration of the barriers and facilitators to self‐managing multiple long‐term conditions amongst people experiencing socioeconomic deprivation
Authors: Woodward Abi , Nimmons Danielle , Davies Nathan , Walters Kate , Stevenson Fiona A. , Protheroe Joanne , Chew‐Graham Carolyn A. , Armstrong Megan 
Published: April 2024

AbstractBackgroundGlobally, it is estimated that one in three adults live with two or more long‐term conditions (multiple long‐term conditions, MLTCs), that require self‐management. People who experience socioeconomic deprivation face significant health inequalities due to a range of interrelated characteristics that lead to a lack of resources and opportunities. Previous research with underserved populations indicate low levels of trust towards primary care providers and potential barriers for developing patient‐healthcare professional relationships. The purpose of this paper is to explore the barriers and facilitators to self‐managing MLTCs, amongst people who experience socioeconomic deprivation.MethodsSemistructured one‐to‐one interviews with adults (n = 28) living in London and Sheffield, United Kingdom with MLTCs who are experiencing socioeconomic deprivation. Participants were recruited through general practices, community channels and social media. Data were analysed in NVivo using reflexive thematic analysis methods.FindingsFour analytical themes were developed: (1) challenges in accessing healthcare services, financial assistance, and cultural awareness; (2) empowerment and disempowerment through technology, including digital exclusion, and use of technology; (3) impact and causes of exclusion on self‐management, including social isolation, area‐based and economic exclusion, and health‐related stigma and (4) adapting self‐management strategies, including cost‐effective, and culturally/lifestyle appropriate strategies.ConclusionsFuture health interventions and services need to be developed with consideration of the combined complexities of managing MLTCs while experiencing socioeconomic deprivation. Increased awareness in practitioners and commissioners of the complexities surrounding the lives of people experiencing socioeconomic deprivation, and the need for targeted strategies to promote self‐management of MLTCs are of great importance.Patient or Public ContributionA patient advisory group contributed to all stages of the study, including providing important feedback on study documents (topic guides and recruitment materials), as well as providing critical insights surrounding the interpretation of interview data.
Academic–practice partnerships in evidence‐based nursing practice: A theory‐guided scoping review
Authors: Halili Xirongguli , Xia Yuting , Li Zeen , Tang Siyuan , Wang Honghong , Chen Qirong 
Published: April 2024

AbstractBackgroundAcademic–practice partnerships have the potential to solve many challenges in evidence‐based nursing practice which is crucial for high‐quality care.AimsTo identify the existing knowledge on academic–practice partnerships in evidence‐based nursing practice.MethodsWe conducted this review following the Joanna Briggs Institute scoping review methodology. We performed a comprehensive literature search of nine databases as well as five websites for gray literature. Two researchers independently conducted literature screening and data extraction and analysis. A third researcher was involved when needed.ResultsDedicated time, dedicated resources, and compatible goals were found to be the top three inputs in academic–practice partnerships for evidence‐based nursing practice. Meeting and discussion were the most popular forms of activities. Sufficient resources were the most important facilitators. Insufficient resources, insufficient time, and communication issues were the top three barriers.ConclusionsThe assumption proposed in the practice–academic partnership logic model (i.e., inputs plus activities can lead to outputs and outcomes) was preliminarily verified by the results of this review in the context of evidence‐based nursing practice. Academic–practice partnerships can leverage the advantages of both sides to overcome barriers and promote evidence‐based nursing practice. However, it is essential to conduct a broader range of high‐quality studies. Such endeavors could offer more comprehensive evidence for refining the framework of academic–practice partnerships in evidence‐based nursing practice.Implications for nursing education, practice, policy and researchThe “theoretical framework of academic–practice partnerships in evidence‐based nursing practice” could theoretically guide academic and clinical nursing staff to collaborate on evidence‐based nursing practice and related research and education programs. The academic–practice partnerships in evidence‐based nursing practice could lead to a win‐win situation for both the academic and the clinical sides. Furthermore, the results of this study provide an evidence‐based foundation for policymakers to develop supportive policies for academic–practice partnerships in evidence‐based nursing practice.
Evaluating Pilot Implementation of ‘PenCS Flu Topbar’ App in Medical Practices to Improve National Immunisation Program–Funded Seasonal Influenza Vaccination in Central Queensland, Australia
Authors: Khandaker Gulam , Chapman Gwenda , Khan Arifuzzaman , Al Imam Mahmudul Hassan , Menzies Robert , Smoll Nicolas , Walker Jacina , Kirk Michael , Wiley Kerrie 
Published: April 2024

ABSTRACTBackgroundThe ‘PenCS Flu Topbar’ app was deployed in Central Queensland (CQ), Australia, medical practices through a pilot programme in March 2021.MethodsWe evaluated the app's user experience and examined whether the introduction of ‘PenCS Flu Topbar’ in medical practices could improve the coverage of NIP‐funded influenza vaccinations. We conducted a mixed‐method study including a qualitative analysis of in‐depth interviews with key end‐users and a quantitative analysis of influenza vaccine administrative data.Results‘PenCS Flu Topbar’ app users reported positive experiences identifying patients eligible for NIP‐funded seasonal influenza vaccination. A total of 3606 NIP‐funded influenza vaccinations was administered in the eight intervention practices, 14% higher than the eight control practices. NIP‐funded vaccination coverage within practices was significantly higher in the intervention practices (31.2%) than in the control practices (27.3%) (absolute difference: 3.9%; 95% CI: 2.9%–5.0%; p < 0.001). The coverage was substantially higher in Aboriginal and Torres Strait Islander people aged more than 6 months, pregnant women and children aged 6 months to less than 5 years for the practices where the app was introduced when compared to control practices: incidence rate ratio (IRR) 2.4 (95% CI: 1.8–3.2), IRR 2.7 (95% CI: 1.8–4.2) and IRR 2.3 (1.8–2.9) times higher, respectively.ConclusionsOur evaluation indicated that the ‘PenCS Flu Topbar’ app is useful for identifying the patients eligible for NIP‐funded influenza vaccination and is likely to increase NIP‐funded influenza vaccine coverage in the eligible populations. Future impact evaluation including a greater number of practices and a wider geographical area is essential.
The effect of maternal sleep quality in late pregnancy on prenatal, birth and early postnatal outcomes
Authors: Abay Halime , Öztürk Gülmez Begüm , Kaplan Sena 
Published: April 2024

SummaryThis cross‐sectional study investigated the effect of maternal sleep quality in late pregnancy on prenatal, birth and early postnatal outcomes. The research was conducted in three parts with women at 28 or more weeks of gestation. In the first part, pregnant women admitted for delivery were evaluated in terms of eligibility criteria. Pregnant women in the latent phase of labour completed the Prenatal Questionnaire. In the second part, labour follow‐up was performed. The researchers completed the Birth Follow‐up Questionnaire based on observations and hospital birth records. In the third part, mothers were interviewed between the 12th and 24th hour of postnatal. Participants filled out the Postnatal Questionnaire, the Childbirth Experience Questionnaire, and the Pittsburgh Sleep Quality Index (n = 385). The data were analysed using the chi‐square independence test, Fisher test, independent samples t‐test, effect sizes, and binary logistic regression analysis. Participants had a mean maternal sleep quality score of 4.00 ± 1.38. They slept for 7.53 ± 0.92 hr on average. One‐third of the participants were poor sleepers (32.2%). Employed participants were 71.6% less likely to have poor maternal sleep quality than their non‐employed counterparts (odds ratio = 0.29, 95% confidence interval: 0.13–0.62; p = 0.002). The odds of poor maternal sleep quality increased by 13.7% when maternal weight gain during pregnancy increased by 1 kg (odds ratio = 1.14, 95% confidence interval: 1.03–1.26; p = 0.014). Increased maternal sleep quality positively affected the birth process (p < 0.05). Healthcare professionals should routinely screen the maternal sleep quality of pregnant women and increase their sleep hygiene.
Changes in species richness with climate change in subalpine communities are dependent on regional environmental conditions and local functional composition
Authors: Michalet Richard , Delpy Ida , Eisenberg Auriane , Hostein Colin , Touzard Blaise , Gross Nicolas , Pottier Julien 
Published: April 2024

AbstractQuestionsClimate change may have different effects on species richness depending on regional climates, soil types and the functional composition of local communities.LocationSubalpine belt of the Grandes Rousses (Alps) and Sancy mountain ranges (the Massif Central), France.MethodsWe compared changes in species richness in response to recent climate change in communities from two mountain ranges subjected to contrasting environmental conditions, with a more continental climate and drier soils in the Alps than in the Massif Central. Vegetation composition of 189 and 157 plots was assessed in 1997 and 2017–2018 in the Alps and 1988–1989 and 2022 in the Massif Central, respectively. Five species traits (height, lateral spread, leaf area, specific leaf area and leaf dry matter content) were measured on 108 and 144 species, respectively. Changes in vegetation composition and species richness along spatial environmental gradients were analysed with correspondence analysis at the Sancy site and canonical correspondence analysis at the Alpe d'Huez site. Changes in functional composition across sites were analysed with principal components analysis. Changes in species richness with climate change were analysed with repeated‐measure ANOVAs.ResultsIn both mountain ranges summer temperatures increased and the hydric balance decreased over the past three decades, but snow cover duration decreased in the Alps only, whereas irradiance strongly increased in the Massif Central only. Functional composition was characterized by shorter and more conservative species in the Alps than in the Massif Central, which was dominated by tall exploitative species. Species richness overall decreased with climate change by ca 10% in the Alps but overall increased by ca 10% in the Massif Central. Species richness decreased in the Alps probably because of increasing competition induced by dwarf shrub encroachment due to decreasing snow cover duration, whereas species richness increased in the Massif Central probably due to increasing irradiance in a very nebulous climate.ConclusionThe opposite changes in species richness observed in the two mountain ranges with recent climate change were likely to be explained by their contrasting climate and soil conditions driving different functional compositions and diversity–environment relationships.
IMF screws with orthodontic E chains as a novel technique for intermaxillary fixation
Authors: Baptist Joanna , Parachuri Venkatesh Naidu , Shetty Premalatha , Madhu Sandeep Kalarikal 
Published: April 2024

AbstractIntroductionEither in conservative or in surgical management of maxillo‐mandibular fractures, intermaxillary fixation (IMF) provides stable occlusion, while offering reduction in the fractured segments. Various techniques have been used for achieving IMF, among which Erich arch bar is the most conventional and routinely used technique. However, it poses a risk of percutaneous injury to the surgical team with every wire used in the technique, causes trauma to the periodontium of the teeth secured by wires and it is not very comfortable for the patient. The few IMF techniques that are recommended without wire require special armamentarium that are not universally available.Materials and MethodsOur novel IMF technique employing multiple looping of orthodontic E chains around IMF screws can provide adequate reduction and stabilization of the fractured segments with good occlusion before plating of the maxillo‐mandibular fractures. It can also be utilized for extended periods for closed reduction or postoperatively for guiding the occlusion.ResultsAs seen in our clinical experience using this novel technique, there is no risk of percutaneous injury to the surgical team. It provides stable occlusion, optimal reduction in the fractured segments and is accepted well by patients as no wires are used.ConclusionThis novel technique can be used in all patients who require IMF and is particularly useful in patients with periodontally compromised teeth or in those who are partially edentulous where conventional arch bar fixation cannot be performed. This technique will considerably reduce the operative time and aid in better patient compliance.
RNA M6A modification shaping cutaneous melanoma tumor microenvironment and predicting immunotherapy response
Authors: Wu Yanhong , He Hongying , Zheng Kairong , Qin Zhenxin , Cai Naikun , Zuo Shuguang , Zhu Xiao 
Published: April 2024

AbstractRecent years have seen rising mortality rates linked to cutaneous melanoma (SKCM), despite advances in immunotherapy. Understanding RNA N6‐methyladenosine (M6A) significance in SKCM is crucial for prognosis, tumor microenvironment (TME), immune cell presence, and immunotherapy efficacy. We analyzed 23 M6A regulators using SKCM samples from TCGA and GEO databases, identifying three M6A modification patterns linked to TME cell infiltration. Principal component analysis (PCA) yielded an M6A score for individual tumors, utilizing patient gene expression profiles and CNV data from TCGA. M6A modification patterns play a crucial role in SKCM development and progression, influencing tumor attributes such as inflammatory stage, subtype, TME interstitial activity, and genetic mutations. The M6A score independently predicts patient outcomes and correlates with improved response to immunotherapy, validated across anti‐PD‐1 and anti‐PD‐L1 therapy cohorts. M6A modifications significantly impact the TME landscape, with the M6A score serving as a predictive marker for immunotherapy response. Integrating M6A‐related information into clinical practice could revolutionize SKCM management and treatment strategies.
“It was classed as a nonemergency”: Women's experiences of kidney disease and preconception decision‐making, family planning, and parenting in the United Kingdom during COVID‐19
Authors: Laughlin Leah Mc , Noyes Jane , Neukirchinger Barbara , Williams Denitza , Phillips Rhiannon , Griffin Sian 
Published: April 2024

AbstractObjectivesTo investigate the experiences of women with kidney disease, residing in the United Kingdom (UK), living through the first 18 months of the COVID‐19 pandemic with specific focus on preconception decision‐making, family planning, and parenting.MethodsWe conducted a mixed‐methods study, comprising an online survey and follow‐up interviews, with UK‐resident women aged 18–50.ResultsWe received 431 surveys and conducted 30 interviews. Half (n = 221, 51%) of the survey respondents considered that COVID‐19 influenced the quality of communication with healthcare professionals and 68% (n = 295) felt that the pandemic disrupted their support networks. Interview participants indicated that delayed and canceled appointments caused anxiety, grief, and loss of pregnancy options. Women's perception of themselves as (good) mothers as well as their capacity to have and raise a child, meet partners, and sustain healthy relationships was negatively affected by the “clinically extremely vulnerable” label. Women's trust in their healthcare was dismantled by miscommunication and variation in lockdown rules that caused confusion and increased worry. Women reported that COVID‐19 contributed to postnatal depression, excessive concern over infant mortality, preoccupation over others following rules, and catastrophising.ConclusionSome women in the UK with chronic kidney disease lost or missed their opportunity to have children during the pandemic. Future pandemic planners need to look more holistically and longer term at what is and is not classed as an emergency, both in how services are reconfigured and how people with chronic conditions are identified, communicated with, and treated.
Assessing perspectives on an intervention connecting adolescents in outpatient psychiatry care to contraceptive counseling in the United States
Authors: Underwood Abigail L. , Hyzak Kathryn A. , Ebersole Ashley , Bunger Alicia C. , Berlan Elise D. 
Published: April 2024

AbstractBackgroundAdolescents with psychiatric disorders have high rates of unintended pregnancy and experience barriers to accessing sexual and reproductive health (SRH) care. Outpatient psychiatry visits are potential opportunities to connect adolescents to SRH care. This study informs the development of the Link2BC intervention which links adolescents in outpatient psychiatry care to SRH care.MethodsWe conducted group interviews with adolescents (3 groups, 7 total participants) and caregivers (3 groups, 9 total participants) and individual interviews with 8 psychiatry providers who received or provided outpatient psychiatric treatment in clinics in a pediatric hospital in a city in the Midwestern United States. We asked questions about the acceptability of Link2BC, potential implementation needs, and implementation determinants. Using consensus‐building techniques, two coders analyzed transcriptions using a codebook informed by the Consolidated Framework for Implementation Research 2.0.ResultsParticipants agreed on the need for interventions that expand access to SRH care. Adolescents emphasized that services should be confidential and accessible and were open to their psychiatrists introducing SRH topics during appointments. Providers expressed preference for training and clear workflows. Participants agreed that psychiatry providers could serve as liaisons between adolescents and their caregivers to facilitate conversations about contraception. Participants had concerns about time constraints during visits but mentioned few other barriers to the intervention.ConclusionThis study demonstrates the acceptability of connecting adolescents in outpatient psychiatry care to contraceptive counseling and informs the refinement and implementation of Link2BC. Integrating contraception counseling in outpatient psychiatry settings is an innovative approach to prevent unintended pregnancy among adolescents by increasing access to SRH care services.
Optimal risk management considering environmental and climatic changes
Authors: Benkraiem Ramzi , El‐Khatib Youssef , Fan Jun , Goutte Stéphane , Klein Tony 
Published: April 2024

AbstractClimate change presents challenges to policy and economic stability, necessitating effective trading strategies to reduce environmental risks. This article addresses gaps in existing studies by using a Markov‐switching model to consider climate risk. Backward stochastic differential equations are used to optimize utility with three hedging strategies based on the concept of risk aversion. Numerical scenarios confirm the model's superiority in incorporating exogenous events, with our risk‐averse strategy outperforming classical approaches. Our strategy outperforms classical strategies by taking a flexible risk trading when investors face risk‐averse behavior due to climate risk events. The findings presented in this article have important implications for the development of more resilient investment portfolios and can contribute to climate policy.
Extended symmetry analysis of (1+2)‐dimensional fine Kolmogorov backward equation
Authors: Koval Serhii D. , Popovych Roman O. 
Published: April 2024

AbstractWithin the class of (1+2)‐dimensional ultraparabolic linear equations, we distinguish a fine Kolmogorov backward equation with a quadratic diffusivity. Modulo the point equivalence, it is a unique equation within the class whose essential Lie invariance algebra is five‐dimensional and nonsolvable. Using the direct method, we compute the point symmetry pseudogroup of this equation and analyze its structure. In particular, we single out its essential subgroup and classify its discrete elements. We exhaustively classify all subalgebras of the corresponding essential Lie invariance algebra up to inner automorphisms and up to the action of the essential point‐symmetry group. This allowed us to classify Lie reductions and Lie invariant solutions of the equation under consideration. We also discuss the generation of its solutions using point and linear generalized symmetries and carry out its peculiar generalized reductions. As a result, we construct wide families of its solutions parameterized by an arbitrary finite number of arbitrary solutions of the (1+1)‐dimensional linear heat equation or one or two arbitrary solutions of (1+1)‐dimensional linear heat equations with inverse square potentials.
The impact of non‐disclosure of HIV status and antiretroviral therapy on HIV recency testing and incidence algorithms
Authors: van den Berg Karin , Murphy Edward L. , Maartens Gary , Louw Vernon J. , Grebe Eduard 
Published: April 2024

AbstractBackground and ObjectivesAccurate HIV incidence estimates among blood donors are necessary to assess the effectiveness of programs aimed at limiting transfusion‐transmitted HIV. We assessed the impact of undisclosed HIV status and antiretroviral (ARV) use on HIV recency and incidence estimates using increasingly comprehensive recent infection testing algorithms.Materials and MethodsUsing 2017 donation data from first‐time and lapsed donors, we populated four HIV recency algorithms: (1) serology and limiting‐antigen avidity testing, (2) with individual donation nucleic amplification testing (ID‐NAT) added to Algorithm 1, (3) with viral load added to Algorithm 2 and (4) with ARV testing added to Algorithm 3. Algorithm‐specific mean durations of recent infection (MDRI) and false recency rates (FRR) were calculated and used to derive and compare incidence estimates.ResultsCompared with Algorithm 4, progressive algorithms misclassified fewer donors as recent: Algorithm 1: 61 (12.1%); Algorithm 2: 14 (2.8%) and Algorithm 3: 3 (0.6%). Algorithm‐specific MDRI and FRR values resulted in marginally lower incidence estimates: Algorithm 1: 0.19% per annum (p.a.) (95% confidence interval [CI]: 0.13%–0.26%); Algorithm 2: 0.18% p.a. (95% CI: 0.13%–0.22%); Algorithm 3: 0.17% p.a. (95% CI: 0.13%–0.22%) and Algorithm 4: 0.17% p.a. (95% CI: 0.13%–0.21%).ConclusionWe confirmed significant misclassification of recent HIV cases when not including viral load and ARV testing. Context‐specific MDRI and FRR resulted in progressively lower incidence estimates but did not fully account for the context‐specific variability in incidence modelling. The inclusion of ARV testing, in addition to viral load and ID‐NAT testing, did not have a significant impact on incidence estimates.