bluuebunny/crossref_metadata_2025_split huggingface dataset:
Utilization of Phyo Referral Score in assessing maternal referral quality in emergency cesarean section of maternal COVID-19 cases in Pekanbaru, Indonesia
Authors: Lubis Ilham Sejahtera , Ganap Eugenius Phyowai 
Published: March 2024

Link of Video Abstract: https://youtu.be/H8GILKBIJwo

Introduction: During the Coronavirus disease 2019 (COVID-19) pandemic, basic and emergency obstetric healthcare was hampered due to health service protocol changes. The reduced coverage of antenatal service during the COVID-19 pandemic increased the number of undetected high-risk pregnancies and the likelihood of obstetric emergency cases. This study assessed maternal referral quality using the Phyo Referral Score (PRS) on emergency cesarean section (ECS) patients infected by SARS-CoV-2.
Methods: This retrospective cohort study used secondary data originating from patient medical records who went through ECS from 1 January 2021 to 31 December 2021. The subject was chosen purposively by the inclusion criteria. A Total of 609 mothers went through Cesarean Section in 2021, there were 52 mothers who met the criteria. The data were described by frequencies, percentages, and mean ± standard deviation. The data was analyzed by Levene’s test and Chi-square test using IBM SPSS version 26.0.
Results: During the retrospective year, a total of 609 mothers went through Cesarean Section in 2021, there were 52 mothers who met the criteria. The most common indications of ECS were persistent fetal hypoxia (50.0%), placenta previa (13.5%), and maternal respiratory failure (13.5%). Most of the patients had good referral quality. From the parameters of PRS, patients are more likely to have good referral quality if accompanied by medical staff, receiving stabilization procedures, and communicating with the hospital by phone before being referred, and transported by ambulance within the same cities.
Conclusion: Accessibility is a critical component of obstetric emergency cases. Even during the COVID-19 pandemic, ensuring that mothers have a good referral quality to access advanced obstetrical care can help the survival of both mothers and fetuses.
Correlation between the degree of severity and type of intracranial hemorrhage with the incidence of coagulopathy in head injuries at the Ulin Regional General Hospital, Banjarmasin, Indonesia
Authors: Lahdimawan Ardik , Handoko Arif , Noor Meitria Syahadatina , Wibowo Agung Ary , Gusasi Sulandri , Sikumbang Kenanga Marwan , Siagian Andreas 
Published: March 2024

Link of Video Abstract: https://youtu.be/iUu03npEjEo

Background: Trauma cases, especially head injuries, are cases that are often found in hospital emergency departments. Coagulopathy can occur in head injuries and intracranial bleeding, where a low Glasgow Coma Scale (GCS) is associated with coagulopathy. This study aims to evaluate the correlation between the degree of severity and type of intracranial hemorrhage and the incidence of coagulopathy in head injuries at the Ulin Regional General Hospital, Banjarmasin, Indonesia.
Methods: An observational analytic study with 74 sample populations was conducted among patients with a head injury treated at Ulin Regional General Hospital, Banjarmasin, in the 2019-2022 period taken by total sampling, which met the inclusion and exclusion criteria. The data of each variable was analyzed with the Kruskal-Wallis test. Data were analyzed using SPSS version 25.0 for Windows.
Results: There was a significant relationship between the two variables towards the occurrence of coagulopathy; namely, the degree of severity was 0.000 (p <0.05), and the type of bleeding was 0.003 (p<0.05).
Conclusion: There is a significant relationship between the degree of severity of the incidence of coagulopathy and the bleeding with the incidence of coagulopathy, so knowing the degree of severity by clinical examination of GCS and the type of intracranial bleeding by CT scan of the head, as well as blood tests to determine the incidence of coagulopathy are important so that management can be carried out and assessing outcomes.
Increased 8-OHdG in umbilical cord blood represents the risk of preeclampsia with Intra-Uterine Growth Restriction (IUGR)
Authors: Ola Andi Nurul Faizah Tenri , Lukas Efendi , Riu Deviana Soraya , Previana Rina , Sunarno Isharyah , Mappaware Nasrudin Andi , Chalid Maisuri Tadjuddin 
Published: March 2024

Link of Video Abstract: https://youtu.be/VsAy9X8XIAk

Background: Preeclampsia is a pregnancy-related disease involving multi-organs, characterized by increased blood pressure in the second trimester of pregnancy. Preeclampsia can have short-term and long-term consequences for the mother and the fetus, including intra-uterine growth restriction (IUGR). One of the markers of DNA damage due to oxidative stress due to endothelial dysfunction in preeclampsia is the increase in 8-OHdG levels in cord blood. This study aims to see an increase in 8-OHdG levels in preeclampsia.
Methods: This study was a cross-sectional study with a total of 41 patients with preeclampsia and 41 patients with healthy pregnant women at Wahidin Sudirohusodo Hospital and its network. Samples were taken using the purposive sampling method according to the inclusion criteria. This 8-OHdG level was examined using the ELISA kit at the HUMRC laboratory of Hasanuddin University Hospital. The data is then processed statistically using SPSS.
Results: This study found 6 patients with PE + IUGR, 31 with PE, and 41 without PE. The examination results of 8-OHdG levels found significant differences between the 3 groups PE + IUGR, PE, and normal pregnancies, which showed a significant relationship between elevated 8-OHdG levels and the incidence of PE accompanied by IUGR (p = 0.006)
Conclusion: Elevated 8-OHdG levels are found in preeclampsia, especially in preeclampsia accompanied by IUGR.
Aquaporin-4 expression related to hydrocephalus severity in hydrocephalus mice model
Authors: Balafif Fachriy , Parenrengi Muhammad Arifin , Suryaningtyas Wihasto , Fauziah Dyah , Sudiana I Ketut , Utomo Budi 
Published: March 2024

Link of Video Abstract: https://youtu.be/h1rynQ_AAaY

Background: Aquaporin-4 (AQP4), a water channel protein, is important in regulating brain water distribution. We hypothesized that increased expression of AQP4 in the kaolin-induced hydrocephalic mice brain is associated with the severity of hydrocephalus. This study aims to evaluate the AQP4 expression related to hydrocephalus severity in hydrocephalus mice model
Methods: Hydrocephalus was induced in 8-10 weeks Sprague-Dawley mice by kaolin injection into cisterna magna. The mice were randomly divided into normal control and hydrocephalus groups and were sacrificed on days 7, 14, and 21 after kaolin induction. The brains were analyzed for AQP4 expression by histological and immunohistochemistry analysis. Data were analyzed using SPSS version 25.0 for Windows.
Results: Histopathological analysis showed an increase in AQP4 expression in periventricular zone astrocytes with the duration of hydrocephalus (p < 0.001). A significant difference in AQP4 expression in this study was found in the hydrocephalus group between the 7th and 14th days (p = 0.023), 7th and 21st days (p < 0.001), and 14th and 21st days (p = 0.044) after kaolin induction. The highest expression of AQP4 was found in the hydrocephalus induction group on day 21.
Conclusion: The results showed that the expression of AQP4 increased with the severity of hydrocephalus. Expression of AQP4 in the kaolin-induced hydrocephalic mice brain was significantly altered depending on the length of time after kaolin induction. Changes in AQP4 expression in periventricular zone astrocytes may be a compensatory mechanism resulting in drainage of CSF accumulation.
Complete resolution of hyperopic shift in anterior capsular contraction syndrome after Nd:YAG laser capsulotomy: a case report
Authors: Intifada  , Indri Wahyuni  , Hermawan Dicky 
Published: March 2024

Link of Video Abstract: https://youtu.be/UfCbUNzPIRE

Background: Anterior capsular contraction syndrome (ACCS) is a disorder in which the anterior capsulectomy opening shrinks excessively. One of the many factors that have been discovered to aggravate the problem is a lack of zonular support for the lens capsule. The prognosis for non-progression of contractions after Nd:YAG anterior capsulotomy is quite excellent. This study aims to present a complete resolution of the hyperopic shift in an anterior capsular contraction syndrome (ACCS), a rare complication of cataract surgery.
Case Illustration: This case report presented a 63-year-old female who developed ACCS in the right eye two years after uncomplicated cataract surgery and intraocular lens implantation. A moderate hyperopic shift of +3.00 D was noted in the affected eye at the initial presentation. Slit-lamp examination revealed an anterior capsule opacification and anterior capsular contraction with fibrosis surrounding the capsulorhexis opening. Ocular and systemic past medical history was unremarkable, and no known risk factors associated with contraction syndrome were found. Nd:YAG laser capsulotomy with six relaxing incisions was performed to release the anterior capsular contraction. Two weeks following capsulotomy, the patient’s visual acuity remarkably improved to LogMAR 0.00 without correction. The hyperopia was completely resolved, and a decrease in anterior chamber depth compared to pre-capsulotomy measurement was noted. ACCS is a possible complication following capsulorrhexis performed in uneventful cataract surgery, which may occur in patients with no known ocular or systemic risk factors. ACCS is commonly asymptomatic, and hyperopic shift is a rare manifestation of ACCS. The backward shift of the intraocular lens (IOL) induces hyperopia due to the anterior capsule contraction. The preferred treatment for ACCS is relaxing incisions using Nd:YAG laser capsulotomy.
Conclusion: Hyperopic shift in ACCS is a rare complication of cataract surgery. However, prompt treatment of contraction release with Nd:YAG laser capsulotomy effectively restored visual function.
Conventional Magnetic Resonance Imaging (MRI) and histopathology agreement for the diagnosis of intracranial meningioma at Dr. Soetomo General Hospital, Surabaya, January 2016–December 2021: a single center study
Authors: Hakim Muhammad Wildan , Wahyuhadi Joni , Utomo Sri Andreani , Fauzi Asra Al , Parenrengi Muhammad Arifin , Utomo Budi 
Published: March 2024

Link of Video Abstract: https://youtu.be/OG7qXwNHzHQ

Background: Meningioma, a prevalent intracranial neoplasm, ranks among the most frequently encountered tumors within the cranial cavity. The utilization of Magnetic Resonance Imaging (MRI) in the diagnostic process of meningioma has proven to be highly valuable. This study aims to evaluate the Conventional-MRI and histopathology agreement for the diagnosis of intracranial meningioma at Dr. Soetomo General Hospital, Surabaya.
Methods: This study presents a diagnostic test and retrospective case-control analysis to evaluate the precision of head MRI in diagnosing intracranial meningioma, as confirmed by histopathological examination. The research was conducted at Dr. Soetomo Surabaya General Hospital from January 2016 to December 2021. Sample size calculations were performed on a cohort of patients diagnosed with intracranial meningioma who underwent head magnetic resonance imaging (MRI) scans and histopathological examinations at the Radiology and Anatomical Pathology Installation of Dr. Soetomo General Hospital. Only patients who satisfied the predetermined inclusion and exclusion criteria were included in the study. Data were analyzed using SPSS version 25.0 for Windows.
Results: At the time of diagnosis, it was observed that the average diameter of grade II/III meningioma was 6.6 ± 1.5 cm, which was found to be greater than the average diameter of grade I meningioma, measuring 4 ± 1.92 cm. The prevalence of grade I meningioma was higher in the skull base region higher in the skull base region, accounting for approximately 36% of cases. Conversely, grade II/III meningioma was found more frequently in the non-skull base area, constituting approximately 76% of cases. In our investigation, it was observed that there exists a higher occurrence of irregular border shape in grade II/III meningioma, accounting for approximately 75% of cases, as compared to grade I meningioma, which only accounts for 14.2% of cases. The presence of contrast enhancement in meningiomas can provide valuable insights into their histological grade. Grade II/III meningiomas exhibit a higher degree of contrast enhancement, which is observed to be heterogeneously distributed in approximately 75% of cases.
Conclusion: This study highlights the potential of MRI as a valuable tool in assessing the grade of meningioma while emphasizing the importance of considering other diagnostic modalities and clinical factors to ensure accurate diagnosis and treatment decisions.
Prevalence angle of trunk rotation in adolescents: a study from an idiopathic scoliosis school screening in Surabaya
Authors: Rangkuti Dicky Lukman , Subagio Eko Agus , Utomo Budi , Parenrengi Muhammad Arifin , Suryaningtyas Wihasto , Rahardjo Paulus 
Published: March 2024

Link of Video Abstract: https://youtu.be/GtRgpMD7tsM

Background: Adolescent idiopathic scoliosis (AIS) is the most common type of scoliosis. The condition begins in early puberty, affects 1-3% of adolescents, and randomly affects young women. Scoliosis screening is still a hot topic discussed by various researchers, especially in the school child population, and it is still an important preventive program to reduce the progression of spinal deformity. This study aims to determine the prevalence rate angle of trunk rotation in idiopathic scoliosis school screening in Surabaya.
Methods: This research is a cross-sectional study with a descriptive observational type using surveys and examinations. In this study, the sample used was 405 junior high school students in Surabaya. The sampling method is cluster random sampling, where each member of the population is divided into subclasses with the school as the cluster. Samples were randomly selected from each area of Surabaya. Data were analyzed using SPSS version 25.0 for Windows.
Results: These data found that the age distribution of the scoliosis screening study was an average of 13.87 years and a median of 14 years. The gender distribution of the scoliosis screening study sample was more female, 211 samples (52.1%) compared to men, 194 samples (47.9%). The distribution was obtained from 405 total samples; 2 positive samples were obtained during the Adam's Forward Bend Test, both 14 years old and female. On examination with a scoliometer, both showed 9 and 11 degrees, respectively. The prevalence angle of trunk rotation in idiopathic scoliosis school screening in Surabaya was 0.49%.
Conclusion: This figure is lower than several studies conducted in several other countries. This may be obtained due to differences in the number of research samples undertaken in each country.
Red Blood Cell Distribution Width (RDW) as a predictor of septic shock in children
Authors: Nastiti Prima Hari , Khalida Nadiah Raini , Setyaningtyas Arina , Kusumastuti Neurinda Permata 
Published: March 2024

Link of Video Abstract: https://youtu.be/Exh1T2szfoE

Background: Septic shock is a prevalent PICU condition requiring prompt intervention. Using the PELOD II score, which has multiple characteristics to examine, it is challenging to predict prognosis in healthcare-limited settings. A link has recently been shown between red blood cell distribution width (RDW) and mortality risk in critically ill patients, albeit the exact mechanism is unknown.
Methods: This retrospective observational study examined RDW values in pediatric septic or non-septic shock patients. This study examined patient clinical features, RDW hematological markers (RDW-CV, RDW-SD, and RDW/albumin ratio), and the area under the curve to determine the cut-off for the hematological marker, sensitivity, and specificity.
Results: Sixty-one pediatric patients met the inclusion criteria (33 with septic shock and 28 with non-septic shock). The red cell distribution width coefficient variation (RDW-CV) (p=0,058), red cell distribution width standard deviation (RDW-SD) (p=0,05), and RDW Albumin Ratio (RAR) (p=0,014) were shown to be significantly different between the septic shock and non-septic shock groups. The cut-off value for RDW-CV was 15.3% (53.6% sensitivity and 97% specificity), 47.4 fl for RDW-SD (64.3% sensitivity and 84.8% specificity), and 5.65 for RDW/albumin ratio (71.4% sensitivity and 84.8% specificity). RDW-CV odd ratio was 36.9 (95% confidence interval (CI) 4.41-308.96, p 0.001), RDW-SD odd ratio was 10.08 (95% confidence interval (CI) 2.95-34.34, p 0,001), and RDW/albumin ratio was 14.00 (95% confidence interval (CI) 3.98-49.16, p 0,001).
Conclusion: Increased RDW can be one marker in pediatric patients with septic shock. Increased levels of RDW/albumin ratio are significantly associated with the incidence of septic shock. Through the (ROC) area under the curve, the RDW/albumin ratio has better capabilities compared to other predictor markers.
Profile of neck penetrating injury patients at Dr. Soetomo general hospital, Surabaya: A case series
Authors: Utomo Heningtyas Suci , Wibowo Marjono Dwi 
Published: March 2024

Link of Video Abstract: https://youtu.be/Tk7yWllByJQ

Background: Neck penetrating injuries are a life-threatening emergency. To date, one of the areas of ongoing controversy is whether all penetrating neck wounds in Zone II still require surgical exploration or whether patients can be managed non-operatively. An approach with absolute exploratory management for every penetrating neck wound results in a substantially reduced mortality rate.
Case Description: We presented 5 cases of neck penetrating injury patients. In the first case, a 33-year-old man presented with a neck wound, hoarseness and subcuticular emphysema; the patient underwent colli exploration. In the second case, a 39-year-old man presented with multiple wounds in the neck, hematemesis and subcuticular emphysema; the patient underwent colli exploration. In the third case, a 27-year-old male patient presented with an 8 cm long open wound on the anterior colli, a visible rupture of cricoid and thyroid cartilage; the patient underwent tracheostomy and debridement. In a fourth case, a 37-year-old male patient presented with a 12 cm long sutured wound in the anterior colli, hoarseness, emphysema and air bubbling from the wound; the patient underwent colli exploration. In the fifth case, a 41-year-old male patient presented with a 7 cm long sutured wound at the anterior colli and a defect on thyroid cartilage; the patient underwent colli exploratory surgery.
Conclusion: A hard sign was obtained in all five cases, and immediate colli exploration was performed without diagnostic supportive examination. The decision to perform surgery is now based on the presence or absence of "hard signs" of a penetrating neck wound.
A case of chromoblastomycosis caused by Fonsecaea pedrosoi: challenge in diagnosis
Authors: Indranarum Trisiswati , Axelia Presstisa Gifta , Sandhika Willy , Listiawan Muhammad Yulianto , Ervianti Evy 
Published: March 2024

Link of Video Abstract: https://youtu.be/9CxOCuDn4f4

Background: Chromoblastomycosis (CBM) is a chronic, granulomatous mycosis of the skin and subcutaneous tissue produced by the traumatic inoculation of various dematiaceous fungi. CBM lesions are clinically polymorphic and often misdiagnosed as multiple infectious and noninfectious diseases. Early diagnosis and prompt treatment of CBM are important to prevent further complications. This case study aims to evaluate the chromoblastomycosis caused by Fonsecaea pedrosoi as a challenge in diagnosis.
Case Presentation: A male, 47 years old, came to the dermatovenereology clinic with a chief complaint of a wound on his right leg 17 years ago. The skin appeared thicker and scaly and felt rough. He also complained of pain and itch on the wound. Dermatological examination revealed multiple verrucous erythematous plaques, sized 10x20 cm, irregular with a well-defined and elevated border and black punctum. Results of potassium hydroxide, culture, and histopathology examination confirmed CBM with F. pedrosoi as the etiological agent. The patient was treated with a favorable outcome with oral itraconazole, local thermotherapy, and CO2 laser.
Conclusion: The diagnosis of Chromoblastomycosis remains a challenge because lesions are clinically polymorphic and often misdiagnosed as various infectious and noninfectious diseases. Physicians should raise awareness of CBM as one of the differential diagnoses for chronic wounds. This case also showed that the combination treatment of itraconazole with adjuvant thermotherapy and CO2 laser had a favorable outcome.
Tetanus patient profiles and factors affecting clinical outcomes at Dr. Soedono general hospital, Madiun in 2019-2020
Authors: Setiyandari Bernadeta Hernik , Winantyo Tjahjo , Ali Iskandar 
Published: March 2024

Link of Video Abstract: https://youtu.be/VC3Gcd7oS5Y

Introduction: Tetanus is a disease that can be diagnosed clinically. However, there is a lack of research data on tetanus patients and their clinical outcomes, especially in adult tetanus patients in Indonesia. This study aims to determine the factors that influence the outcome of tetanus patients.
Method: A cross-sectional study was performed from May to June 2021 at Dr. Soedono Madiun General Hospital. Subjects were recruited by total sampling. The data that will be taken in this study are gender, age, immunization history, incubation period, onset, port of entry, Philips score, and clinical outcomes of patients.
Result: Were 112 patients diagnosed with tetanus at Dr. Soedono General Hospital from January 2019 to December 2020. The male subjects outnumbered female subjects by 81.3%. The youngest subject was 19 years old, and the oldest was 81 years old. The tetanus immunization status showed that 2 patients were known to be fully immunized, 21 were not fully immunized, and 89 (79.5%) had unknown immunization status. This study showed that the port of entry of the wound is most often the entry point for tetanus in the inferior extremity of 72 patients (64.3%). Most onset occurred in 1-7 days, with a mean onset for generalized tetanus was 2.3 ± 1.8 days. The mean incubation period for the appearance of tetanus symptoms in this study was 9.4 ± 5.6 days. The most common comorbid disease in this study was diabetes mellitus (11.6%). This study's clinical outcome of tetanus showed that 74 patients (66.1%) had improved, while 38 patients (33.9%) died during treatment.
Discussion: This study's most common port of entry was on the inferior extremities. This lower limb predominance as the port of entry could be explained by the fact that C. tetani exists in soil; hence, any lower limb injury would be open to contamination and infection by this organism. Based on the Dakar and Phillips score system, tetanus has a worse prognosis when there is a faster incubation period, faster onset, more proximal port of entry location, immunization status, comorbidities and signs of muscle spasm, fever, and tachycardia are obtained.
Conclusion: In this study, tetanus still has a high mortality rate. Male gender, age over 45, a moderate to severe disease degree (considering a relatively short incubation time, short onset period, and unknown immunization status) are a few factors that may affect this high mortality rate.