bluuebunny/crossref_metadata_2025_split huggingface dataset:
An Efficient Synthesis of (.+‐.)‐Lycoricidine Featuring a Stille—IMDAF Cycloaddition Cascade.
Authors: Zhang Hongjun , Padwa Albert 
Published: May 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Titanium(II)‐Mediated Cyclizations of (Silyloxy)enynes: A Total Synthesis of (‐)‐7‐Demethylpiericidin A1.
Authors: Keaton Katie A. , Phillips Andrew J. 
Published: May 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Synthesis of (4R,5S)‐Melithiazols B and M.
Authors: Akita Hiroyuki , Sasaki Takamitsu , Takayama Hiroyuki , Kato Keisuke 
Published: May 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Total Synthesis of Ecteinascidin 743.
Authors: Chen Jinchun , Chen Xiaochuan , Bois‐Choussy Michele , Zhu Jieping 
Published: May 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
A Stereoselective Synthesis of (4E,7S)‐(—)‐7‐Methoxydodec‐4‐enoic Acid.
Authors: Li Yang , Chen Jie , Cao Xiao‐Ping 
Published: May 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Resource Recovery from Nd—Fe—B Sintered Magnet by Hydrothermal Treatment.
Authors: Itakura Takeshi , Sasai Ryo , Itoh Hideaki 
Published: May 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Fabrication of Au@CaCO3 Nanoparticles by in situ Mineralization in Hydrogel Microspheres.
Authors: Kuang Min , Wang Dayang , Moehwald Helmuth 
Published: May 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
The Properties of Co2Cr1‐xFexAl Heusler Compounds
Authors: Felser Claudia , Elmers Hans‐Joachim , Fecher Gerhard H. 
Published: May 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Magnetism and Structure of Magnetic Multilayers Based on the Fully Spin Polarized Heusler Alloys Co2MnGe and Co2MnSn
Authors: Westerholt K. , Bergmann A. , Grabis J. , Nefedov A. , Zabel H. 
Published: May 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Nanogranular Phase Formation During Devitrification of Fe(NiCo)ZrB Amorphous Alloys
Authors: Idzikowski B. , Szajek A. 
Published: May 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Octahedral Rhenium Cluster Chemistry: From High‐Temperature Syntheses to the Elaboration of New Inorganic/Molecular Hybrid Compounds via Solution Route
Authors: Pilet Guillaume , Perrin Andre 
Published: May 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Structure and Magnetic Properties of Co/CoO and Co/Si Core‐Shell Cluster Assemblies Prepared via Gas Phase
Authors: Sumiyama Kenji , Hihara Takehiko , Peng Dong Liang , Katoh Ryoji 
Published: May 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Immobilizing Catalysts on Porous Materials
Authors: Zhao X. S. , Bao Xiao Ying , Guo Wanping , Lee Fang Yin 
Published: May 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Bifunctional Transition Metal Based Molecular Catalysts for Asymmetric Syntheses
Authors: Ikariya Takao , Murata Kunihiko , Noyori Ryoji 
Published: May 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Ruthenium Indenylidene Complexes. Metathesis Catalysts with Enhanced Activity
Authors: Dragutan Valerian , Dragutan Ileana , Verpoort Francis 
Published: May 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
The Application of Manganese Complexes of Ligands Derived from 1,4,7‐Triazacyclononane in Oxidative Catalysis
Authors: Sibbons Kevin F. , Shastri Kirtida , Watkinson Michael 
Published: May 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
MK‐0431 : Agent for Type 2 Diabetes and Dipeptidyl‐peptidase IV (CD26) Inhibitor
Authors: Sorbera L. A. , Castaner J. 
Published: May 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Recent Developments of Heterogeneous Solid Catalysts for Liquid‐Phase Friedel—Crafts‐Type Benzylation Reactions
Authors: Jana Suman K. 
Published: May 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Heteropoly Acids, Their Salts and Polyoxometalates as Heterogeneous, Efficient and Ecofriendly Catalysts in Organic Reactions: Some Recent Advances
Authors: Firouzabadi H. , Jafari A. A. 
Published: May 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Mechanism of a New Dihalocyclopropane‐(dihalomethyl)vinyl Rearrangement
Authors: Jankowski C. K. , Bou Laouz A. , Diaz‐Torres E. , Lesage Denis , Belanger J. M. R. , Pare J. R. J. 
Published: May 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
From Dysfunction to Bis‐function: Design and Applications of Functionalized Ionic Liquids
Authors: Fei Zhaofu , Geldbach Tilmann J. , Zhao Dongbin , Dyson Paul J. 
Published: May 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Proteomics of Metal Transport and Metal‐Associated Diseases
Authors: Kulkarni Prasad P. , She Yi Min , Smith Scott D. , Roberts Eve A. , Sarkar Bibudhendra 
Published: May 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Natural Products from Medicinal Plants: Non‐Alkaloidal Natural Constituents of the Thalictrum Species
Authors: Khamidullina Elena A. , Gromova Alexandra S. , Lutsky Vladislav I. , Owen Noel L. 
Published: May 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
An Overview on the Development of a Bio‐Artificial Pancreas as a Treatment of Insulin‐Dependent Diabetes Mellitus
Authors: Silva Ana Isabel , Norton de Matos Antonio , Brons I. Gabrielle , Mateus Marilia 
Published: May 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Time‐Resolved Micro Liquid Desorption Mass Spectrometry: Mechanism, Features, and Kinetic Applications
Authors: Charvat Ales , Boegehold Andreas , Abel Bernd 
Published: May 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
A Trypanosoma cruzi antigen signals CD11b+ cells to secrete cytokines that promote polyclonal B cell proliferation and differentiation into antibody‐secreting cells
Authors: Montes Carolina L , Acosta‐Rodríguez Eva V , Mucci Juan , Zuniga Elina I , Campetella Oscar , Gruppi Adriana 
Published: May 2006

AbstractMicrobial‐induced polyclonal activation of B cells is a common event in several forms of infections, and is believed to play a crucial role both for enhancing the production of specific antibodies and for maintenance of B cell memory. Therefore, a major challenge in biomedical research is the identification of pathogen‐derived products capable of rapidly mounting B cell expansion and differentiation. Here we report that glutamate dehydrogenase (GDH) stimulates polyclonal proliferation and differentiation of naive B cells. This stimulation was found to be T cell independent, but to absolutely require CD11b+ cells. Moreover, we demonstrate that stimulation of CD11b+ cells by GDH leads to the production of IL‐6, IL‐10 and B cell‐activating factor (BAFF), all of which combine to powerfully induce B cell expansion. Importantly, IL‐6 and IL‐10 further drive B cell terminal differentiation into plasma cells by up‐regulating critical transcription factors and immunoglobulin secretion. Our data provide the first evidence that a protozoan antigen can induce BAFF production by accessory cells, which in concert with other cytokines trigger polyclonal B cell activation.
Thermal Behaviour of Selected C10H16 Monoterpenes
Authors: Stolle Achim , Brauns Claudia , Nüchter Matthias , Ondruschka Bernd , Bonrath Werner , Findeisen Matthias 
Published: May 2006

AbstractThe presented work investigates the thermal behaviour of selected monoterpenes under various reactor temperatures and residence times (carrier gas, reactor inserts). In addition to the analysis of the liquid products by capillary GC and GC‐MS, chemical derivatisation techniques (Diels–Alder reaction, hydrogenation) were used to identify the liquid‐phase products. A thermal conversion of β‐pinene (1), myrcene (2) and limonene (4) in a reaction network is presented and the experimental evidence for the formation of pyrolysis products by a biradical pathway is discussed. The reaction network was modified based on the identification of additional C10H16 terpene isomers. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2006)
Synthesis of Alkynyl‐Substituted Nitronyl Nitroxides through an Organosilicon Derivative
Authors: Tretyakov Eugene , Romanenko Galina , Podoplelov Alexei , Ovcharenko Victor 
Published: May 2006

Abstract4,4,5,5‐Tetramethyl‐2‐[2‐(trimethylsilyl)ethynyl]imidazolidine‐1,3‐diol has been synthesized and oxidized to the corresponding nitronyl nitroxide (1). Further removal of the trimethylsilyl group gave the 2‐ethynyl‐substituted nitronyl nitroxide 2. Both 1 and 2 are labile compounds. With certain precautions, however, they may be purified from admixtures and be obtained as single crystals, thanks to which X‐ray diffraction study confirmed that molecules 1 and 2 each contain a triple bond. The accessibility of these spin‐labeled acetylenes makes it possible to synthesize other derivatives of nitroxides, as was demonstrated in the case of 1,3‐dipolar cycloaddition of CH2N2 to 1 and 2, which gave the corresponding pyrazolyl‐substituted nitronyl nitroxides. These were synthesized in a one‐pot synthesis strategy, since the solutions of spin‐labeled alkynes 1 and 2 formed in the course of synthesis are stable for a long time. The reaction between CH2N2 and 1, containing the (CH3)3Si substituent, was much more sluggish and mainly gave the 4‐pyrazolyl‐substituted nitronyl nitroxide, isolated as an individual compound and also identified by X‐ray crystallography. In the same reaction with 2, the product was the 3‐pyrazolyl‐substituted nitronyl nitroxide. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2006)
Chiral separations by capillary electrophoresis: Recent developments and applications
Authors: Van Eeckhaut Ann , Michotte Yvette 
Published: May 2006

AbstractThis paper provides an overview of the different classes of chiral selectors that are used in CE. The main properties of every class are described, together with the mechanism of enantioseparation. Newly introduced selectors are also discussed. Pharmaceutical and biomedical applications published from January 2004 till March 2005 are summarized.
A new method of competitive reverse transcription polymerase chain reaction with SYBR Gold staining for quantitative analysis of mRNA
Authors: Oba Rieko , Kudo Yasuko , Sato Naomi , Noda Reiko , Otsuka Yuzuru 
Published: May 2006

AbstractThere are several methods available to analyze the mRNA concentration quantitatively. Among them, the competitive reverse transcription (RT‐)PCR method is very useful. For this method, Cy5‐labeled primers were used, and after gel electrophoresis in 7 M urea, the Cy5‐labeled single‐strand DNA was measured by a fluorescence detector. However, as the equipment to measure the Cy5‐labeled fluorescence is expensive, we developed a new method using SYBR Gold staining. After gel electrophoresis in 7 M urea, the single‐strand PCR product DNA was stained with SYBR Gold, and photographed with a standard UV‐transilluminator and a standard digital camera with a specific filter for SYBR Gold staining. The photographic image was digitized by an imaging software. We measured β‐actin and plasma glutathione peroxidase (Gpx3) mRNA concentrations of HepG2 cell cultured at 5 and 20% oxygen tension. The Gpx3 expression was increased by hypoxia. The result was equivalent to the data obtained by the real‐time PCR analysis.
Fabrication of a gold microelectrode for amperometric detection on a polycarbonate electrophoresis chip by photodirected electroless plating
Authors: Kong Yong , Chen Hengwu , Wang Yurong , Soper Steven A. 
Published: May 2006

AbstractA novel method of photoresist‐free micropatterning coupled with electroless gold plating is described for the fabrication of an integrated gold electrode for electrochemical detection (ED) on a polycarbonate (PC) electrophoresis microchip. The microelectrode layout was photochemically patterned onto the surface of a PC plate by selective exposure of the surface coated without photoresist to 254 nm UV light through a chromium/quartz photomask. Thus, the PC plate was selectively sensitized by formation of reactive chemical moieties in the exposed areas. After a series of wet chemistry reactions, the UV‐exposed area was activated with a layer of gold nanoparticles that served as a seed to catalyze the electroless plating. The gold microelectrode was then selectively plated onto the activated area by using an electroless gold plating bath. Nonselective gold deposition on the unwanted areas was eliminated by sonication of the activated PC plate in a KSCN solution before electroless plating, and the adhesion of the plated electrodes to the PC surface was strengthened with thermal annealing. Compared with the previously reported electroless plating technique for fabrication of microelectrodes on a microchip, the present method avoided the use of a membrane stencil with an electrode pattern to restrict the area to be wet‐chemically sensitized. The CE with integrated ED (CE‐ED) microchip was assembled by thermal bonding an electrode‐plated PC cover plate to a microchannel‐embossed PC substrate. The novel method allows one to fabricate low‐cost, electrode‐integrated, complete PC CE‐ED chips with no need of a clean room. The fabricated CE‐ED microchip was demonstrated for separation and detection of model analytes, including dopamine (DA) and catechol (CA). Detection limits of 0.65 and 1.03 μM were achieved for DA and CA, respectively, and theoretical plate number of 1.4×104 was obtained for DA. The plated gold electrode can be used for about 4 h, bearing usually more than 100 runs before complete failure.
An analysis of therapist treatment effects: Toward providing feedback to individual therapists on their clients' psychotherapy outcome
Authors: Okiishi John C. , Lambert Michael J. , Eggett Dennis , Nielsen Lars , Dayton David D. , Vermeersch David A. 
Published: May 2006

AbstractThis study examined data collected on over 5,000 clients seen by 71 therapists over a 6‐year period in a University Counseling Center. Clients were given the Outcome Questionnaire‐45 (OQ‐45) on a session‐by‐session basis to track their treatment response. Data were also collected on therapists' theoretical orientation, years of experience, gender, and type of training. Data were analyzed using hierarchical linear modeling (HLM) to see if general therapist traits (i.e., theoretical orientation, type of training) accounted for differences in clients' rate of improvement. Data were then analyzed, again using HLM with therapists as a fixed effect, to compare individual therapists to see if there were significant differences in the efficiency of treatment. In addition, pre‐ minus posttest OQ‐45 scores were examined to see if there were differences in the overall outcome of clients. There was a significant amount of variation among therapists' clients' rates of improvement. Therapist feedback reports were generated to summarize client outcome for individual providers in contrast to center averages and in an attempt to improve client outcome. © 2006 Wiley Periodicals, Inc. J Clin Psychol 62: 1157–1172, 2006.
Stochastic cancer progression driven by non‐clonal chromosome aberrations
Authors: Heng Henry H. Q. , Stevens Joshua B. , Liu Gou , Bremer Steven W. , Ye Karen J. , Reddy Prem‐Veer , Wu Gen Sheng , Wang Y. Alan , Tainsky Michael A. , Ye Christine J. 
Published: May 2006

AbstractCancer research has previously focused on the identification of specific genes and pathways responsible for cancer initiation and progression based on the prevailing viewpoint that cancer is caused by a stepwise accumulation of genetic aberrations. This viewpoint, however, is not consistent with the clinical finding that tumors display high levels of genetic heterogeneity and distinctive karyotypes. We show that chromosomal instability primarily generates stochastic karyotypic changes leading to the random progression of cancer. This was accomplished by tracing karyotypic patterns of individual cells that contained either defective genes responsible for genome integrity or were challenged by onco‐proteins or carcinogens that destabilized the genome. Analysis included the tracing of patterns of karyotypic evolution during different stages of cellular immortalization. This study revealed that non‐clonal chromosomal aberrations (NCCAs) (both aneuploidy and structural aberrations) and not recurrent clonal chromosomal aberrations (CCAs) are directly linked to genomic instability and karyotypic evolution. Discovery of “transitional CCAs” during in vitro immortalization clearly demonstrates that karyotypic evolution in solid tumors is not a continuous process. NCCAs and their dynamic interplay with CCAs create infinite genomic combinations leading to clonal diversity necessary for cancer cell evolution. The karyotypic chaos observed within the cell crisis stage prior to establishment of the immortalization further supports the ultimate importance of genetic aberrations at the karyotypic or genome level. Therefore, genomic instability generated NCCAs are a key driving force in cancer progression. The dynamic relationship between NCCAs and CCAs provides a mechanism underlying chromosomal based cancer evolution and could have broad clinical applications. J. Cell. Physiol. 208: 461–472, 2006. © 2006 Wiley‐Liss, Inc.
Multiple apoptotic pathways induced by p53‐dependent acidification in benzo[a]pyrene‐exposed hepatic F258 cells
Authors: Huc Laurence , Rissel Mary , Solhaug Anita , Tekpli Xavier , Gorria Morgane , Torriglia Alicia , Holme Jørn A. , Dimanche‐Boitrel Marie‐Thérèse , Lagadic‐Gossmann Dominique 
Published: May 2006

AbstractPolycyclic aromatic hydrocarbons (PAH), such as benzo[a]pyrene (B[a]P), are ubiquitous genotoxic environmental pollutants. Their DNA‐damaging effects lead to apoptosis induction, through similar pathways to those identified after exposure to other DNA‐damaging stimuli with activation of p53‐related genes and the involvement of the intrinsic apoptotic pathway. However, at a low concentration of B[a]P (50 nM), our previous results pointed to the involvement of intracellular pH (pHi) variations during B[a]P‐induced apoptosis in a rat liver epithelial cell line (F258). In the present work, we identified the mitochondrial F0F1‐ATPase activity reversal as possibly responsible for pHi decrease. This acidification not only promoted executive caspase activation, but also activated leucocyte elastase inhibitor/leucocyte‐derived DNase II (LEI/L‐DNase II) pathway. p53 appeared to regulate mitochondria homeostasis, by initiating F0F1‐ATPase reversal and endonuclease G (Endo G) release. In conclusion, a low dose of B[a]P induced apoptosis by recruiting a large panel of executioners apparently depending on p53 phosphorylation and, for some of them, on acidification. J. Cell. Physiol. 208: 527–537, 2006. © 2006 Wiley‐Liss, Inc.