bluuebunny/crossref_metadata_2025_split huggingface dataset:
Stress conditions extend maternal care and delay juvenile development in crayfish
Authors: Kaur Davinder , Das Koushik , Kubec Jan , Buřič Miloš 
Published: April 2024

Abstract
Maternal care in crayfish has been extensively studied, but little is known of its response to environmental factors. We studied the duration of maternal care and its association with the juvenile development of marbled crayfish Procambarus virginalis in adverse environmental conditions. We exposed females with developmental stage 3 juveniles to environments of low water volume (LW) with food provided, low water volume with no feed (starvation) (LWS), and low water volume without feeding plus an intruder (red swamp crayfish male) (LWSI). A control group with standard water level/feed conditions was included for comparison. Groups were monitored for up to 90 days. The LWS group showed significantly prolonged maternal care (~65 days) as indicated by an extended attachment phase, delayed moulting of mothers (~53 days), and retarded juvenile development. In the LWSI group, conflict precluded extended maternal care. Low use of shelter and feeding was evident under all stress conditions. The results showed that crayfish females modify maternal care in accordance with conditions, providing a longer period of safety for offspring under adverse circumstances. It is possible that the expression of maternal pheromones can manipulate the developmental rate in juveniles, a topic for future research.
Mid-term outcomes of right ventricular papillary muscle approximation for severe functional tricuspid regurgitation
Authors: Ito Chihiro , Kohno Hiroki , Matsuura Kaoru , Watanabe Michiko , Inui Tomohiko , Matsumiya Goro 
Published: April 2024

Abstract

OBJECTIVES
Recurrence of tricuspid regurgitation (TR) after tricuspid annuloplasty can occur in cases where a dilated right ventricle exists and subsequent leaflet tethering follows. We previously reported a new technique of the right ventricular papillary muscle approximation (RV-PMA) for functional TR associated with leaflet tethering. The objective of this study is to elucidate the mid-term outcomes and evaluate the durability of RV-PMA.

METHODS
Between January 2014 and March 2023, we applied RV-PMA in 20 patients of advanced functional TR with severe leaflet tethering. The indication of the technique was severe TR with leaflet tethering height &gt;8 mm, and/or a right ventricular end-diastolic diameter &gt;45 mm. The patients were followed up with echocardiography before discharge and at annual interval thereafter.

RESULTS
There was no perioperative mortality. In the echocardiography performed before discharge, TR was decreased to mild or less in 85%, and a significant improvement in right ventricular end-diastolic diameter and tethering height were achieved (53–45 mm and 11.1–4.4 mm, respectively). Furthermore, during the median 3-year follow-up period, TR was kept controlled mild or less in 80% of the cases.

CONCLUSIONS
RV-PMA is considered to be a safe, effective and durable technique as an additional approach for tricuspid annuloplasty.
Integrative analysis of the methylome and transcriptome of tomato fruit (Solanum lycopersicum L.) induced by postharvest handling
Authors: Zhou Jiaqi , Zhou Sitian , Chen Bixuan , Sangsoy Kamonwan , Luengwilai Kietsuda , Albornoz Karin , Beckles Diane M 
Published: April 2024

Abstract
Tomato fruit ripening is triggered by the demethylation of key genes, which alters their transcriptional levels thereby initiating and propagating a cascade of physiological events. What is unknown is how these processes are altered when fruit are ripened using postharvest practices to extend shelf-life, as these practices often reduce fruit quality. To address this, postharvest handling-induced changes in the fruit DNA methylome and transcriptome, and how they correlate with ripening speed, and ripening indicators such as ethylene, abscisic acid, and carotenoids, were assessed. This study comprehensively connected changes in physiological events with dynamic molecular changes. Ripening fruit that reached ‘Turning’ (T) after dark storage at 20°C, 12.5°C, or 5°C chilling (followed by 20°C rewarming) were compared to fresh-harvest fruit ‘FHT’. Fruit stored at 12.5°C had the biggest epigenetic marks and alterations in gene expression, exceeding changes induced by postharvest chilling. Fruit physiological and chronological age were uncoupled at 12.5°C, as the time-to-ripening was the longest. Fruit ripening to Turning at 12.5°C was not climacteric; there was no respiratory or ethylene burst, rather, fruit were high in abscisic acid. Clear differentiation between postharvest-ripened and ‘FHT’ was evident in the methylome and transcriptome. Higher expression of photosynthetic genes and chlorophyll levels in ‘FHT’ fruit pointed to light as influencing the molecular changes in fruit ripening. Finally, correlative analyses of the -omics data putatively identified genes regulated by DNA methylation. Collectively, these data improve our interpretation of how tomato fruit ripening patterns are altered by postharvest practices, and long-term are expected to help improve fruit quality.
Experiences from targeted removal of farmed Atlantic salmon from Norwegian rivers
Authors: Skolgund Helge , Kambestad Marius , Normann Eirik Straume , Wiers Tore , Lehmann Gunnar Bekke , Urdal Kurt , Barlaup Bjørn Torgeir , Vollset Knut Wiik 
Published: April 2024

Abstract
Farmed salmon escaping from aquaculture and interbreeding with wild conspecifics pose a significant threat to the genetic integrity of natural salmon populations. Despite advancements in aquaculture security, escape incidents persist, prompting the need for effective mitigation strategies. This study summarizes experiences from efforts to remove escaped farmed salmon over a 12-year period in 63 western Norwegian rivers, using either (1) spearfishing during snorkelling by trained personnel or (2) traditional fishing methods employed by local groups. Recaptured farmed salmon ranged widely in size and included both spawners as well as immature fish, demonstrating that farmed fish entering rivers comprise fish of different ages and escape histories. Traditional fishing by locals recaptured the highest number of farmed fish, while removal during snorkelling in general captured larger and mature fish. On average, 53% of the farmed salmon observed during snorkelling were recaptured. This efficacy was influenced by the number of farmed fish present and the size of the farmed fish. In addition, efficacy increased over time, indicating that the removal team became more efficient. The study underscores that active removal, when executed judiciously, contributes to reducing the ecological risks associated with escaped farmed fish, complementing broader strategies for sustainable aquaculture.
Active and passive smoking and breast cancer in Japan: a pooled analysis of nine population-based cohort studies
Authors: Wada Keiko , Nagata Chisato , Utada Mai , Sakata Ritsu , Kimura Takashi , Tamakoshi Akiko , Sugawara Yumi , Tsuji Ichiro , Sato Ren , Sawada Norie , Tsugane Shoichiro , Oze Isao , Ito Hidemi , Kitamura Tetsuhisa , Koyanagi Yuriko N , Lin Yingsong , Matsuo Keitaro , Abe Sarah K , Inoue Manami ,   for the Research Group for the Development and Evaluation of Cancer Prevention Strategies in Japan, Inoue Manami , Abe Sarah Krull , Sawada Norie , Tanaka Shiori , Kimura Takashi , Sugawara Yumi , Mizoue Tetsuya , Nomura Shuhei , Takimoto Hidemi , Ito Hidemi , Matsuo Keitaro , Lin Yingsong , Wada Keiko , Kitamura Tetsuhisa , Sakata Ritsu , Tanaka Keitaro , Charvat Hadrien , Hidaka Akihisa , Hirabayashi Mayo , Iwasaki Motoki , Kitamura Yuri , Mori Nagisa , Muto Michihiro , Nagata Chisato , Naito Mariko , Nakayama Tomio , Nishino Yoshikazu , Sadakane Atsuko , Saito Eiko , Sasazuki Shizuka , Shimazu Taichi , Shimizu Hiroyuki , Sugiyama Kemmyo , Suzuki Hidekazu , Tamakoshi Akiko , Tsubono Yoshitaka , Tsuji Ichiro , Tsugane Shoichiro , Utada Mai , Wakai Kenji , Yamagiwa Yoko , Yamaji Taiki 
Published: April 2024

Abstract

Background
Epidemiological studies have shown inconsistent results regarding the link between smoking and breast cancer risk, despite the biological plausibility of a positive association.

Methods
Participants were 166 611 women from nine prospective cohort studies in Japan which launched in 1984–1994 and followed for 8–22 years. Information on smoking and secondhand smoke was obtained through self-administered baseline questionnaires. Breast cancer was defined as code C50 according to the International Classification of Diseases for Oncology, 3rd Edition or the International Classification of Diseases, 10th Revision. After adjusting for several potential confounders, relative risks for breast cancer were calculated in the individual studies according to the current or previous status of active and passive smoking using Cox regression, followed by a summary estimate of hazard ratios using random-effects meta-analyses.

Results
Of the 60 441 participants who reported being premenopausal and 106 170 who reported being postmenopausal at baseline, 897 and 1168 developed breast cancer during follow-up, respectively. Compared with never smokers, current smokers had a higher risk of developing breast cancer before the age of 50 years. In addition, ever smokers who started smoking at 30 years of age or younger, or who started smoking before first childbirth, had a higher risk of developing breast cancer before the age of 50 years. No association between adulthood or childhood exposure to secondhand smoke and breast cancer was observed.

Conclusion
Smoking may increase the risk of premenopausal breast cancer, and smoking earlier in life might be especially harmful. The impact of secondhand smoke needs further investigation.
Optimization of combustion strategy for application of sustainable fuels regarding elimination of vehicles emission footprint
Authors: Puškár Michal , Kopas Melichar 
Published: April 2024

Abstract
Nowadays, transport generates a significant portion of greenhouse gas emissions and at the same time it is also one of the dominant polluters within urban agglomerations. However, vehicles with piston combustion engines are still the most popular choice of consumers thanks to the unquestionable advantages of these engines. There are currently several hundred million cars driven by combustion engines in EU-countries, and approximately one-and-a-half billion of worldwide. The only possible way to reduce the emission footprint of automotive transport while at the same time keeping the current fleet of combustion engine vehicles, is the application of synthetic fuels. Of course, hydrogen will have its place in the new green economy. A very promising idea is the low temperature combustion (LTC) technology. This technology combines the high efficiency of modern combustion engines with utilization of climate-neutral fuels. Therefore, the LTC technology can be a suitable solution for the sustainable future of the current vehicle fleet. The presented scientific article is focused on the development of dual-fuel technology, specifically on optimization of combustion conditions as well as on design of a new geometrical shape of the combustion chamber regarding minimization of engine emissions. This article also introduces a unique LTC system, which is characterized by significant achievements in reducing emissions. This innovative system together with design of a new geometrical shape are the subjects of patent protection.
Slow Dissent and Worldmaking beyond Imperial Relations in “Kamer-amère” (Bitter Cameroon)
Authors: Murrey Amber 
Published: April 2024

Abstract
Working in the subfields of postcolonial geographies of responsibility and Black and African Geographies, my analysis centers on Cameroonian political resistance and practices of worldmaking. From January 2016 to August 2023, political activists experienced a set of difficulties: A wariness and oftentimes hostility to France’s continued support for the authoritarian state, dismissals by state representatives that dissenters were “externally supported,” and misappropriations of the anti-imperial mantel by government representatives. Over the preceding several decades, the state fostered a political environment antagonistic toward Cameroonians of the diaspora, and this was instrumentalized in the widespread dismissal of activists as foreign, foreign-backed, or foreign-influenced. Activists were hesitant but sometimes strategically prepared to call upon transnational groups for attention and political action against repression and violence in Cameroon. In the context of the state’s appropriation of an anti-imperialist ideology, I argue that transnational solidarities must be attuned to and integrated with local politics in Cameroon. Making sense of popular debates regarding (anti)imperialism, (anti)intervention, and transnational solidarity in conditions of authoritarianism matters for political debates across the African continent.
Cheap Tweets?: Crisis Signaling in the Age of Twitter
Authors: Harris Benjamin Norwood , Lin-Greenberg Erik 
Published: April 2024

Abstract
World leaders are increasingly turning to social media to engage in crisis signaling. This raises important questions about the effects of emerging communication technologies on international politics. In particular, are threats issued via social media seen as more or less credible than those issued through traditional channels such as government press releases? Using survey experiments fielded both on unique samples of foreign policy experts in the United States, India, and Singapore and on US public samples, we find that threat medium generally generates no significant difference in perceived credibility among national security experts and members of the public. Put differently, tweeted threats are not seen as “cheaper talk” than threats issued through more traditional channels. This project extends work on crisis signaling, elite decision-making, and the domestic politics of international relations by taking into account an increasingly common technology.
Transcriptome data reveal beneficial effects of Rickettsia (Rickettsiales: Rickettsiaceae) on Bemisia tabaci
(Hemiptera: Aleyrodidae) through nutritional factors and defense mechanisms
Authors: Li Yi-Han , Peng Jing , Wu Qing-Jun , Sun Jing-Chen , Zhang Peng-Jun , Qiu Bao-Li 
Published: April 2024

Abstract
Whitefly Bemisia tabaci (Hemiptera: Aleyrodidae) is a destructive insect pest of many crops. Rickettsia infection in different cryptic species of B. tabaci has been observed worldwide. Understanding the interactions between these 2 organisms is critical to developing Rickettsia-based strategies to control B. tabaci and thereby reduce the transmission of related vector-borne viruses. In this study, we investigated the effects of Rickettsia infection on the biological characteristics of the Middle East Asia Minor 1 (MEAM1) strain of B. tabaci through biological analysis of infected and uninfected individuals. The results of this study suggest that Rickettsia may confer fitness benefits. These benefits include increased fertility, improved survival rates, accelerated development, and resulted in female bias. We also investigated the transcriptomics impact of Rickettsia infection on B. tabaci by performing a comparative RNA-seq analysis of nymphs and adult females, both with and without the infection. Our analysis revealed 218 significant differentially expressed genes (DEGs) in infected nymphs compared to uninfected ones and 748 significant DEGs in infected female adults compared to their uninfected whiteflies. Pathway analysis further revealed that Rickettsia can affect many important metabolic pathways in whiteflies. The results suggest that Rickettsia plays an essential role in energy metabolism, and nutrient synthesis in the B. tabaci MEAM1, and depends on metabolites obtained from the host to ensure its survival. Overall, our findings suggest that Rickettsia has beneficial effects on B. tabaci and offered insights into the potential molecular mechanisms governing the interactions between Rickettsia and B. tabaci MEAM1.
Milanese antique dealers and the international market
Authors: Colombi Martina 
Published: April 2024

Abstract
This article provides two concrete examples of the opening of the Milanese art market to the international stage at the time of Gian Giacomo Poldi Pezzoli. The main focus is on the career of Giuseppe Baslini (1817–1887), the most important art dealer in nineteenth-century Milan. A true self-made man, Baslini entertained close relations with the most eminent Milanese collectors of the time, including Poldi Pezzoli and the Bagatti Valsecchi brothers; his success was secured by the international market on three major axes – London, Paris and Berlin. The second example concerns the family company of the Grandi art dealers, during the same years. In 1877 Baslini’s brothers-in-law Carlo (1842–1914) and Antonio (1857–1923) Grandi inherited the company of their father, Antonio (1810–1877), which originally specialized in Old Master drawings and prints, but extended its interests to paintings and objets d’art soon after Baslini’s death. The Grandi correspondence, preserved by the heirs and recently donated to the Fondo per l’Ambiente Italiano, has provided the opportunity to reconstruct their business, which had an international dimension from its inception.
‘Caregivers’ Experiences of a Singing Training Program to Support Person-Centered Dementia Care
Authors: Stuart-Röhm Karyn , Clark Imogen N , Baker Felicity A 
Published: April 2024

Abstract
Music-based interventions are acknowledged to be accessible and beneficial to people living with dementia. As part of an over-arching research project exploring the contributions of person-centered caregiver singing (PCCS) intervention to caregiver’s provision of care, this study aimed to explore caregiver’s experiences of a PCCS training program. 8 caregivers across 2 care homes in South Africa participated in 4 iterative participatory cycles aimed at refining the training protocol. We completed a thematic analysis of semi-structured interviews of caregivers’ experiences of the training. 3 themes emerged: workshop components contributed to positive learning experiences; caregivers’ increased knowledge and insight into dementia, music, and personhood; and caregivers’ enhanced self-efficacy which encompassed their emotional wellbeing, self-awareness, and confidence. Our study highlights caregivers’ self-efficacy, self-hood, and personhood as valuable benefits in person-centered care training. Caregivers experienced training as both professionally and personally beneficial. While PCCS supported a shift toward a person-centered care approach, further research would help establish approaches to support sustainability of PCCS training and use in wider contexts.
Retracted and Replaced: Increasing power in screening trials by testing control-arm specimens: application to multicancer detection screening
Authors: Katki Hormuzd A , Prorok Philip C , Castle Philip E , Minasian Lori M , Pinsky Paul F 
Published: April 2024

Abstract

Background
Cancer screening trials have required large sample sizes and long time-horizons to demonstrate cancer mortality reductions, the primary goal of cancer screening. We examine assumptions and potential power gains from exploiting information from testing control-arm specimens, which we call the “intended effect” (IE) analysis that we explain in detail herein. The IE analysis is particularly suited to tests that can be conducted on stored specimens in the control arm, such as stored blood for multicancer detection (MCD) tests.

Methods
We simulated hypothetical MCD screening trials to compare power and sample size for the standard vs IE analysis. Under two assumptions that we detail herein, we projected the IE analysis for 3 existing screening trials (National Lung Screening Trial [NLST], Minnesota Colon Cancer Control Study [MINN-FOBT-A], and Prostate, Lung, Colorectal, Ovarian Cancer Screening Trial—colorectal component [PLCO-CRC]).

Results
Compared with the standard analysis for the 3 existing trials, the IE design could have reduced cancer-specific mortality P values 5-fold (NLST), 33-fold (MINN-FOBT-A), or 14 160-fold (PLCO-CRC) or, alternately, reduced sample size (90% power) by 26% (NLST), 48% (MINN-FOBT-A), or 59% (PLCO-CRC). For potential MCD trial designs requiring 100 000 subjects per arm to achieve 90% power for multicancer mortality for the standard analysis, the IE analysis achieves 90% power for only 37 500-50 000 per arm, depending on assumptions concerning control-arm test-positives.

Conclusions
Testing stored specimens in the control arm of screening trials to conduct the IE analysis could substantially increase power to reduce sample size or accelerate trials and could provide particularly strong power gains for MCD tests.
Manual rolling load and low back pain among workers in Japan: a cross-sectional study
Authors: Iwakiri Kazuyuki , Sasaki Takeshi , Du Tanghuizi , Miki Keiichi , Oyama Fuyuki 
Published: April 2024

Abstract

Objectives:
Manual rolling of heavy objects remains in the workplace. The Health and Safety Executive (HSE) in the United Kingdom recommends load weights of &lt;400 kg in the rolling task. However, the association of rolling weights &lt;400 kg with work-related low back pain (LBP) has not been sufficiently investigated. This study examined the effect of rolling loads weighing &lt;400 kg on LBP among Japanese workers.

Methods:
A web-based survey gathered information from 15 158 workers in 2022. Among them, 15 035 did not handle loads, whereas 123 handled rolling weights &lt;400 kg. Load weight was categorized into 4 groups: no-handling (0 kg) and rolling weights of ≤20, 20-40, and &gt;40 kg. Multiple logistic regression analysis examined the association between the subdivided rolling weight and LBP.

Results:
No significant differences in odds ratio (OR) of LBP were found for workers handling ≤40 kg rolling weights compared with that for no-handling workers. However, workers handling &gt;40 kg rolling weights had a significantly greater OR of LBP than those not handling loads.

Conclusions:
Rolling weights between 40 and 400 kg could place a high stress on the lower back. Implementation in Japan of the HSE recommendations regarding rolling load should be carefully considered.
Validity and reliability of Japanese version of the MAPO index for assessing manual patient handling in nursing homes
Authors: Tani Naomichi , Ichikawa Fumiko , Oda Susumu , Menoni Olga , Tasso Marco , Iwakiri Kazuyuki , Kumashiro Masaharu , Ebara Takeshi , Tsutsui Yasuhiro 
Published: April 2024

Abstract

Objectives:
Low back pain (LBP) among caregivers in Japanese nursing homes has long been considered an occupational health issue. This study aimed to verify the reliability and validity of our developed Japanese version of the Movement and Assistance for Hospitalized Patients (J-MAPO) index, a risk assessment tool for LBP, in nursing homes.

Methods:
Two inspectors assessed 15 nursing homes using J-MAPO, and deduced 3 LBP risk levels as follows: low, moderate, and high risk. Caregivers in nursing homes responded to a self-administered questionnaire on LBP over the past 12 months. Data from 296 caregivers with no missing data were used. We further used logistic regression models to analyze the association between LBP as a dependent variable, and J-MAPO risk level as an independent variable. We used Cohen kappa coefficient to assess interrater reliability to further assess the agreement between the 2 inspectors.

Results:
The multivariate logistic regression analysis showed that the adjusted odds ratio and 95% CIs for LBP increased progressively with J-MAPO risk level (Low-risk: 1.00; Moderate-risk: 1.70 [0.74-3.91]; High-risk: 2.67 [1.28-5.56]). Furthermore, the J-MAPO risk levels assessed by the 2 inspectors were in perfect agreement (κ = 1) observed for interrater reliability using Cohen kappa coefficient.

Conclusions:
There was high interrater reliability, and J-MAPO risk levels were associated with LBP. Therefore, our results suggest that the J-MAPO is a useful risk assessment tool for LBP in Japanese nursing homes.