bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effect of organic biostimulants on cannabis productivity and soil microbial activity under outdoor conditions
Authors: Da Cunha Leme Filho Jose F. , Chim Bee K. , Bermand Cameron , Diatta Andre A. , Thomason Wade E. 
Published: March 2024

AbstractIn 2019 and 2020, we investigated the individual and combined effects of two biofertilizers (manure tea and bioinoculant) and one humic acid (HA) product on cannabis biochemical and physiological parameters and soil CO2 evolution under outdoor conditions. Our hypothesis was that HA would increase the microbial activity in the biofertilizers and synergy of both compounds would promote better plant performance and stimulate soil microbial activity. In 2020, the individual and combined application of biofertilizers and HA increased cannabis height, chlorophyll content, photosynthetic efficiency, aboveground biomass, and bucked biomass by 105, 52, 43, 122, and 117%, respectively. Impacts were greater under suboptimal growing conditions caused by planting delay experienced in 2020. In 2019, planting date occurred in-between the most favorable period and chlorophyll content and photosynthetic efficiency were the only parameters influenced by the application of biostimulants. The discrepancies between the two growing seasons reinforce the evidence of other studies that biostimulants efficacy is maximized under stress conditions. This study could not conclusively confirm that the combined use of biofertilizer + HA is a superior practice since affected plant parameters did not differ from application of the compounds singly. Similarly, only one biofertilizer + HA treatment increased soil microbial activity. More research is needed to define optimum rates and combinations of biofertilizer and stimulants for cannabis.
State licenses for medical marijuana dispensaries: neighborhood-level determinants of applicant quality in Missouri
Authors: Yaskewich David M. 
Published: March 2024

Abstract
Background
When state governments impose quotas on commercial marijuana licenses, regulatory commissions use an application process to assess the feasibility of prospective businesses. Decisions on license applications are often met with formal appeals and legal challenges from rejected applicants. Although prior research has examined substate disparities in the availability of marijuana dispensaries, less attention has been given to the quality of license applications. The present study analyzed the relationship between neighborhood-level characteristics and the quality of prospective dispensary businesses.

Methods
During Missouri’s first applicant pool for medical marijuana dispensaries in 2019, a total of 606 census tracts contained the location site of at least one dispensary applicant. Using data from the Missouri Department of Health and Senior Services and the American Community Survey, fractional and binary logistic regression models were used to estimate the relationship between census-tract characteristics and application outcomes.

Results
License applications received higher evaluation scores when proposed dispensary sites were in census tracts with greater population densities and no majority in racial/ethnic composition. Census tracts with poorer socioeconomic conditions attracted a disproportionate share of low-scoring applicants from the bottom quartile of scores. These effects were stronger for certain application subsections, particularly those assessing the quality of an applicant’s business plan and on-site security.

Conclusions
Some communities tend to attract prospective license holders who possess better quality resources, business practices, and industry experience. State disparities in commercial licensing requirements and application processes may lead to the inequities in legal product access found in some prior studies.
Care, management, and use of ferrets in biomedical research
Authors: Pramod Ravindran Kumar , Atul Pravin Kumar , Pandey Mamta , Anbazhagan S. , Mhaske Suhas T. , Barathidasan R. 
Published: March 2024

AbstractThe ferret (Mustela putorius furo) is a small domesticated species of the family Mustelidae within the order Carnivora. The present article reviews and discusses the current state of knowledge about housing, care, breeding, and biomedical uses of ferrets. The management and breeding procedures of ferrets resemble those used for other carnivores. Understanding its behavior helps in the use of environmental enrichment and social housing, which promote behaviors typical of the species. Ferrets have been used in research since the beginning of the twentieth century. It is a suitable non-rodent model in biomedical research because of its hardy nature, social behavior, diet and other habits, small size, and thus the requirement of a relatively low amount of test compounds and early sexual maturity compared with dogs and non-human primates. Ferrets and humans have numerous similar anatomical, metabolic, and physiological characteristics, including the endocrine, respiratory, auditory, gastrointestinal, and immunological systems. It is one of the emerging animal models used in studies such as influenza and other infectious respiratory diseases, cystic fibrosis, lung cancer, cardiac research, gastrointestinal disorders, neuroscience, and toxicological studies. Ferrets are vulnerable to many human pathogenic organisms, like severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), because air transmission of this virus between them has been observed in the laboratory. Ferrets draw the attention of the medical community compared to rodents because they occupy a distinct niche in biomedical studies, although they possess a small representation in laboratory research.
The effects of stress on auditory system: a narrative review
Authors: Emami Seyede Faranak 
Published: March 2024

AbstractBackgroundStress is an integral part of human life, small amounts of which can be effective in adapting to conditions, while its continuous increase is a predisposing factor for all diseases. The aim of this article is to determine the effect of stress on auditory system. The full text of 51 articles published between 2000 and 2023 was extracted from Scopus, PubMed, and Web of Sciences websites and became the source of this research.ResultsPositive and negative emotions cause the release of stress hormones that affect all human cognitive behaviors, perceptions, and peripheral senses. They can have destructive effects on the functioning of the auditory system.ConclusionAbnormal release of stress hormones can increase susceptibility to hearing disorders. A healthy lifestyle is essential to reduce the harmful effects of stress. The most important aspects of a healthy lifestyle are regular and uninterrupted night sleep, drinking enough water, avoiding high amounts of caffeine, a Mediterranean diet, staying away from noise/light/industrial pollution and social crimes, listening to relaxing music and doing movements in harmony with their rhythm, laughing constantly, writing down negative emotions, having true love in life, deep emotional connections with kind people, and receiving positive energy from their intentions.
Systemic lupus erythematosus causes necrosis of the jejunum: a case report
Authors: Fu Dingran , Liu Yunquan , Zhou Shiyong , Lu Jin , Ai Fei 
Published: March 2024

Abstract
Background
Lupus mesenteric vasculitis (LMV) is a serious complication of systemic lupus erythematosus (SLE) that can lead to a range of gastrointestinal issues, such as intestinal bleeding, necrosis, and perforation. The optimal surgical approach for cases of intestinal necrosis in LMV remains a topic of debate.

Case presentation
We present the first documented instance of jejunal necrosis in a 56-year-old woman undergoing SLE treatment. The patient presented with symptoms including abdominal distension, pain, nausea, and vomiting. Physical examination revealed abdominal tenderness, rebound pain, and muscle tension. Following surgery and steroid therapy, the patient experienced successful recovery and was discharged from the hospital.

Conclusions
Patients with jejunal necrosis due to SEL, during intraoperative exploration, surgical decisions should be made based on careful observation. In cases of extensive jejunal necrosis that cannot be preserved, it is advisable to resect the necrotic tissue as much as possible, with a recommended extended resection margin of 2–3 cm.
Disruption of Thyroid Hormone Receptor Thrab Leads to Female Infertility in Zebrafish
Authors: Ai Nana , Han Cho Rong , Zhao Hui , Cheng Sheue-Yann , Ge Wei 
Published: March 2024

Abstract
Thyroid hormones (THs) T4 and T3 are vital for development, growth, and metabolism. Thyroid dysfunction can also cause problems in fertility, suggesting involvement of THs in reproduction. In zebrafish, there exist 2 forms of TH receptor alpha gene (thraa and thrab). Disruption of these genes by CRISPR/Cas9 showed no reproductive irregularities in the thraa mutant; however, inactivation of the thrab gene resulted in female infertility. Although young female mutants (thrabm/m) showed normal ovarian development and folliculogenesis before sexual maturation, they failed to release eggs during oviposition after sexual maturation. This spawning failure was due to oviductal blockage at the genital papilla. The obstruction of the oviduct subsequently caused an accumulation of the eggs in the ovary, resulting in severe ovarian hypertrophy, abdominal distention, and disruption of folliculogenesis. Gene expression analysis showed expression of both TH receptors and estrogen receptors in the genital papilla, suggesting a direct TH action and potential interactions between thyroid and estrogen signaling pathways in controlling genital papilla development and function. In addition to their actions in the reproductive tracts, THs may also have direct effects in the ovary, as suggested by follicle atresia and cessation of folliculogenesis in the heterozygous mutant (thrab+/m), which was normal in all aspects of female reproduction in young and sexually mature fish but exhibited premature ovarian failure in aged females. In summary, this study provides substantial evidence for roles of THs in controlling the development and functions of both reproductive tract and ovary.
“The Book Which Increases the Human Efficiency”
Authors: Hamilton Peter 
Published: March 2024

AbstractThis article reframes the introduction of Taylorism in early Republican China as the origin point for an enduring social ideal of “scientific management” across modern Chinese society. Previous scholars have argued that Taylorism had a limited impact on Chinese industry before the 1920s and 1930s, but this conclusion overlooks a pervasive intellectual impact. A global phenomenon originating in the United States, Taylorism was not just methods to increase production efficiency. It was also a utopian vision to reorganize society around perfected technocratic hierarchies. Its first Chinese translators all enthusiastically embraced this universal vision, promoting this American “science” as a panacea that would both accelerate China's industrialization and improve its supposedly inefficient public. China's first advocates of scientific management spread these ideas far beyond industry through mainstream publications and urged their universal adoption. While Taylor's methods only shaped a few industrial enterprises before the 1920s, they nonetheless seeded a capacious ideal of a scientifically managed society that remains today.
Fitness Level- and Sex-Related Differences in Pulmonary Limitations to Maximal Exercise in Normoxia and Hypoxia
Authors: Raberin Antoine , Manferdelli Giorgio , Schorderet Forrest , Bourdillon Nicolas , Millet Grégoire P. 
Published: March 2024

ABSTRACT

Purpose
Both maximal-intensity exercise and altitude exposure challenge the pulmonary system that may reach its maximal capacities. Expiratory flow limitation (EFL) and exercise-induced hypoxemia (EIH) are common in endurance-trained athletes. Furthermore, due to their smaller airways and lung size, women, independently of their fitness level, may be more prone to pulmonary limitations during maximal-intensity exercise; particularly when performed in hypoxic conditions. The objective of this study was to investigate the impact of sex and fitness level on pulmonary limitations during maximal exercise in normoxia and their consequences in acute hypoxia.

Methods
Fifty-one participants were distributed across four different groups according to sex and fitness level. Participants visited the laboratory on three occasions to perform maximal incremental cycling tests in normoxia and hypoxia (inspired oxygen fraction = 0.14) and two hypoxic chemosensitivity tests. Pulmonary function and ventilatory capacities were evaluated at each visit.

Results
EIH was more prevalent (62.5% vs. 22.2%, p = 0.004) and EFL less common (37.5% vs. 70.4%, p = 0.019) in women than men. EIH prevalence was different (p = 0.004) between groups of trained men (41.7%), control men (6.7%), trained women (50.0%), and control women (75.0%). All EIH men but only 40% of EIH women exhibited EFL. EFL individuals had higher slope ratio (p = 0.029), higher ventilation (V̇E) (p < 0.001), larger ΔVO2max (p = 0.019) and lower hypoxia-related V̇E increase (p < 0.001).

Conclusions
Women reported a higher EIH prevalence than men, regardless of their fitness level, despite a lower EFL prevalence. EFL seems mainly due to the imbalance between ventilatory demands and capacities. It restricts ventilation, leading to a larger performance impairment during maximal exercise in hypoxic conditions.
Ανακυκλώνοντας Καλλιτεχνικά
Authors: Ζιώγας Γιάννης 
Published: March 2024

Η παρούσα έκδοση είναι αποτέλεσμα της δράσης «Ανακυκλώνοντας Καλλιτεχνικά», που διοργανώθηκε από το Κέντρο Περιβαλλοντικής Εκπαίδευσης (ΚΠΕ) Μελίτης- Φλώρινας και το 1ο Εργαστήριο Ζωγραφικής του Τμήματος Εικαστικών και Εφαρμοσμένων Τεχνών (ΤΕΕΤ) του Πανεπιστημίου Δυτικής Μακεδονίας. Η συνεργασία των δύο φορέων ξεκίνησε τον Μάιο του 2010 και συνεχίστηκε τον Μάιο του 2011 με τη διοργάνωση του τριήμερου σεμιναρίου .Φύση/Ορια/ Υλικά.. Η επιτυχία του συγκεκριμένου σεμιναρίου οδήγησε τους δύο φορείς στην απόφαση για συνέχιση της συνεργασίας τους, αυτή τη φορά στο πεδίο της δημιουργικής ανακύκλωσης.
A Flow-Based Formulation for Parallel Machine Scheduling Using Decision Diagrams
Authors: Kowalczyk Daniel , Leus Roel , Hojny Christopher , Røpke Stefan 
Published: March 2024

We present a new flow-based formulation for identical parallel machine scheduling with a regular objective function and without idle time. The formulation is constructed with the help of a decision diagram that represents all job sequences that respect specific ordering rules. These rules rely on a partition of the planning horizon into, generally nonuniform, periods and do not exclude all optimal solutions, but they constrain solutions to adhere to a canonical form. The new formulation has numerous variables and constraints, and hence we apply a Dantzig-Wolfe decomposition to compute the linear programming relaxation in reasonable time; the resulting lower bound is stronger than the bound from the classical time-indexed formulation. We develop a branch-and-price framework that solves three instances from the literature for the first time. We compare the new formulation with the time-indexed and arc time–indexed formulation by means of a series of computational experiments. History: Accepted by Andrea Lodi, Area Editor for Design & Analysis of Algorithms—Discrete. Funding: This work was partially funded by the European Union’s Horizon 2020 research and innovation program under [Marie Skłodowska-Curie Grant 754462]. Supplemental Material: The software that supports the findings of this study is available within the paper and its Supplemental Information ( https://pubsonline.informs.org/doi/suppl/10.1287/ijoc.2022.0301 ) as well as from the IJOC GitHub software repository ( https://github.com/INFORMSJoC/2022.0301 ). The complete IJOC Software and Data Repository is available at https://informsjoc.github.io/ .
Dysregulation of LINC00324 promotes poor prognosis in patients with glioma
Authors: Jin Xin , Zhu Jiandong , Yu Haoyun , Shi Shengjun , Shen Kecheng , Gu Jingyu , Yin Ziqian , Yu Zhengquan , Wu Jiang 
Published: March 2024

Background
LINC00324 is a long-stranded non-coding RNA, which is aberrantly expressed in various cancers and is associated with poor prognosis and clinical features. It involves multiple oncogenic molecular pathways affecting cell proliferation, migration, invasion, and apoptosis. However, the expression, function, and mechanism of LINC00324 in glioma have not been reported.

Material and methods
We assessed the expression of LINC00324 of LINC00324 in glioma patients based on data from The Cancer Genome Atlas (TCGA) and Genotype-Tissue Expression (GTEx) to identify pathways involved in LINC00324-related glioma pathogenesis.

Results
Based on our findings, we observed differential expression of LINC00324 between tumor and normal tissues in glioma patients. Our analysis of overall survival (OS) and disease-specific survival (DSS) indicated that glioma patients with high LINC00324 expression had a poorer prognosis compared to those with low LINC00324 expression. By integrating clinical data and genetic signatures from TCGA patients, we developed a nomogram to predict OS and DSS in glioma patients. Gene set enrichment analysis (GSEA) revealed that several pathways, including JAK/STAT3 signaling, epithelial-mesenchymal transition, STAT5 signaling, NF-κB activation, and apoptosis, were differentially enriched in glioma samples with high LINC00324 expression. Furthermore, we observed significant correlations between LINC00324 expression, immune infiltration levels, and expression of immune checkpoint-related genes (HAVCR2: r = 0.627, P = 1.54e-77; CD40: r = 0.604, P = 1.36e-70; ITGB2: r = 0.612, P = 6.33e-7; CX3CL1: r = -0.307, P = 9.24e-17). These findings highlight the potential significance of LINC00324 in glioma progression and suggest avenues for further research and potential therapeutic targets.

Conclusion
Indeed, our results confirm that the LINC00324 signature holds promise as a prognostic predictor in glioma patients. This finding opens up new possibilities for understanding the disease and may offer valuable insights for the development of targeted therapies.
The impact of epidemic infectious diseases on the relationship between subjective well-being and social class identity in older adults: The mediating role of Self-rated health
Authors: Feng Qianxi , Li Yan , Wan Miao , Li Wei 
Published: March 2024

Background
The purpose of this paper is to explore the relationship between subjective well-being, social class identity, and Self-rated health among older persons,. Focusing on the mediating role of health and the impact of epidemic infectious diseases on these relationships.

Methods
Based on the 2018 and 2021 China General Social Survey (CGSS) databases, the data were screened, and processed. Using Stata17, we employed ordered probit regression to examine the relationships among variables and Bootstrap methods to assess mediation effects, and the CGSS data for 2018 and 2021 were compared and analyzed.

Results
Our results revealed that factors such as social class identity, health status, and personal income significantly positively impact older persons’ subjective well-being (P<0.01). Notably, there was a partial mediating effect of health status between the subjective well-being of the elderly and social class identity. And findings showed that when older adults were affected by epidemic diseases, their subjective well-being, social class identity, and Self-rated health remained significantly positively correlated. Subjective well-being, social class identity. What is more noteworthy is that when affected by epidemic infectious diseases, older adults’ subjective well-being, social class identity, and Self-rated health remained significantly positively correlated. The mediating role of self-rated health in older adults’ subjective well-being and social class identity increased from 9.6% to 12.4%.

Conclusions
In the face of epidemic infectious diseases, we need to pay more attention to the Self-rated health of the elderly, and the Chinese government should take effective measures to improve their health level, which will in turn improve the subjective well-being of the elderly and realize the goal of healthy aging.
Liarmouth: A Feel-Bad Romance, John Waters (2022)
Authors: Stith Kelly 
Published: March 2024

Review of: Liarmouth: A Feel-Bad Romance, John Waters (2022)
New York: Farrar, Straus and Giroux, 256 pp.,
ISBN 978-0-37418-572-5, h/bk, $26.00
ISBN 978-1-25086-723-0, p/bk, $18.00
Male Femininities, Dana Berkowitz, Elroi J. Windsor and C. Winter Han (eds) (2023)
Authors: Allan Jonathan A. 
Published: March 2024

Review of: Male Femininities, Dana Berkowitz, Elroi J. Windsor and C. Winter Han (eds) (2023)
New York: New York University Press, 408 pp.,
ISBN 978-1-47983-961-2, h/bk, $99.00
ISBN 978-1-47980-878-6, p/bk, $35.00
Analisis Potensi Ekonomi Pesantren Berbasis Kewirausahaan melalui Media Wakaf Produktif untuk Pemberdayaan Umat di Masa Pandemi Covid-19
Authors: Annes Nisrina Khoirunnisa  , Muhammad Hanif Ibrahim  , Alifia Nur Zaida  
Published: March 2024

Pandemi Covid-19 memiliki dampak yang signiikan terhadap ekonomi di dunia. berbagai kebijakan diberlakukan guna mengatasi penyebaran Covid-19, seperti physical distancing, social distancing, pemakaian masker, hingga pembatasan sosial berskala besar (PSBB). Terjadinya penurunan aktivitas manusia, para pelaku usaha khususnya usaha mikro, kecil dan menengah tidak sedikit yang mengalami gulung tikar disebabkan melemahnya laju ekonomi. Hal ini disebabkan salah satunya adalah lumpuhnya kegiatan usaha masyarakat. Tujuan penelitian ini yakni mengidentifikasi niat santri/santriwati dalam pengembangan wakaf produktif di lingkungan pesantren selanjutnya wajaf produktif tersebut salah satunya digunakan sebagai pemberdayaan ekonomi umat. Metode yang digunakan dalam penelitian ini yakni pendekatan statistik dengan mengadopsi model Structural Equation Modelling (SEM). Metode pengumpulan data dalam penelitian ini yakni menggunakan kuesioner dengan teknik puposive sampling yang ditujukan kepada seluruh santri dan santriwati di Yogyakarta. Hasil penelitian menunjukkan bahwa religiosity dan knowledge menunjukkan hasil yang signifikan terhadap attitude serta attitude dan perceived behavioral control selanjutnya memengaruhi intention untuk berwakaf secara signifikan. Namun, subjective norm menunjukkan hasil yang tidak signifikan terhadap intention berwakaf di kalangan santri/santriwati. Oleh karena hasil tersebut, maka pegembangan wakaf dikalangan pesantren harus ditingkatkan untuk selanjutnya dimanfaatkan untuk pengembangan ekonomi Umat.
Elder Biaoqing: investigating the indexicalities of memes on Chinese social media
Authors: Lu Ying , Kroon Sjaak 
Published: March 2024

Abstract
This paper adopts a digital ethnographic approach to analyze concrete communicative practices with Elder Biaoqing, a type of graphic semiotic resources comparable to emojis and memes, typically designed for and used by older people on Chinese social media. Following Silverstein’s theorizing, it reveals the emergence of multiple indexicalities of Elder Biaoqing that are a result of several social factors: the growth of an older population online, people’s reflections on their communicative needs engendered by specific social facts, and people’s ethno-metapragmatics. The study of Elder Biaoqing reveals users’ agency in creating semiotic resources, the inequality between digital natives and digital migrants, and age anxiety in Chinese society. The findings invite a re-imagination of social facts – the existence of an online–offline nexus and a re-thinking of theories for sociocultural research in a digital era – ontological perspectives on multimodal resources and digital infrastructures, developments of the theoretical perspective of indexicality, and a total-semiotic-fact approach to digitally mediated social interaction.