bluuebunny/crossref_metadata_2025_split huggingface dataset:
Development of method using language processing techniques for extracting information on drug–health food product interactions
Authors: Yoshizaki Mari , Kuriya Yuki , Yamamoto Masaki , Watanabe Naoki , Araki Michihiro 
Published: March 2024

AimsHealth food products (HFPs) are foods and products related to maintaining and promoting health. HFPs may sometimes cause unforeseen adverse health effects by interacting with drugs. Considering the importance of information on the interactions between HFPs and drugs, this study aimed to establish a workflow to extract information on Drug‐HFP Interactions (DHIs) from open resources.MethodsFirst, Information on drugs, enzymes, their interactions, and known DHIs was collected from multiple public databases and literature sources. Next, a network consisted of enzymes, HFP, and drugs was constructed, assuming enzymes as candidates for hubs in Drug‐HFP interactions (Method 1). Furthermore, we developed methods to analyze the biomedical context of each drug and HFP to predict potential DHIs out of the DHIs obtained in Method 1 by applying BioWordVec, a widely used biomedical terminology quantifier (Method 2‐1 and 2‐2).Results44,965 DHIs (30% known) were identified in Method 1, including 38 metabolic enzymes, 157 HFPs, and 1256 drugs. Method 2‐1 selected 7401 DHIs (17% known) from the DHIs of Method 1, while Method 2‐2 chose 2819 DHIs (30% known). Based on the different assumptions in these methods where Method 2‐1 specifically selects HFPs interacting with specific enzymes and Method 2‐2 specifically selects HFPs with similar function with drugs, the propsed methods resulted in extracting a wide variety of DHIs.ConclusionsBy integrating the results of language processing techniques with those of the network analysis, a workflow to efficiently extract unknown and known DHIs was constructed.
Géographies féministes au Québec, intersectionnalité et décolonialisme : Vers une géographie de l'émancipation?
Authors: Boustani Lama , Latendresse Anne , Martin Patricia 
Published: March 2024

RésuméApparue au milieu des années 1980, la géographie féministe est demeurée en marge de la géographie du Québec, comme s'il s'agissait d'une branche mineure de la géographie. Or, après avoir intégré des préoccupations liées à la géographie des genres et des sexualités, la géographie féministe s'élargit et se consolide sur les plans théorique, épistémologique et méthodologique en intégrant les approches intersectionnelle et décoloniale. Elle se développe à un point tel qu'il est désormais légitime de parler des géographies féministes au Québec. En fait, en adoptant les approches intersectionnelle et décoloniale, les géographies féministes questionnent la construction des discours et du corpus de connaissances constitutifs de la géographie du Québec, connaissances qui se prétendaient universelles. De plus, ces outils analytiques permettent un nouveau regard sur des champs d'intérêts établis dans la géographie du Québec comme les questions migratoires et autochtones, en donnant la parole aux femmes. En ouvrant la voie à la co‐construction des connaissances, ces approches favorisent la visibilité de la complexité des rapports de pouvoir et des rapports à l'espace des différents groupes de population vivant au Québec. En d'autres mots, les géographies féministes, en donnant la parole aux femmes provenant de groupes sociaux subalternes comme les immigrantes et les autochtones, peuvent contribuer à créer une géographie de l'émancipation.
Prescription patterns of ambrisentan in some cities of Colombia
Authors: Valladales‐Restrepo Luis Fernando , Gaviria‐Mendoza Andrés , Machado‐Duque Manuel Enrique , Vallejos‐Narváez Álvaro , Machado‐Alba Jorge Enrique 
Published: March 2024

AbstractIntroductionAmbrisentan is a selective type A endothelin receptor antagonist that has shown significant effectiveness and safety in the management of patients with pulmonary hypertension. Its use pattern with real‐world evidence in Colombia is unknown.ObjectiveThe objective of this study is to determine the prescription patterns of ambrisentan in some cities of Colombia.MethodsA longitudinal descriptive study on the prescription patterns of ambrisentan in patients with pulmonary hypertension (all the groups) was conducted between January 2021 and December 2022 based on a population database of members of the Colombian Health System. Adherence at 1 year was determined using the Medication Possession Ratio (days the drug was dispensed/days from first dispensing to the end of the follow‐up period × 100). Descriptive analysis was carried out.ResultsSixty‐seven patients taking ambrisentan were identified in 10 cities of the country. The individuals had a median age of 51.5 years (interquartile range‐IQR: 39.8–64.0 years), and 82.1% were women. The drug possession rate was 82.2% (IQR: 65.0–96.8%), and persistence at 1 year was present in 49.3% (n = 33) of the cases. The average dose was 8.8 ± 5.0 mg/day, and 76.1% (n = 51) received it in combination therapy, mainly with phosphodiesterase type 5 inhibitors (61.2%, n = 41).ConclusionsAdherence to ambrisentan was good, but its persistence at 1 year was low. The dosages of the drug used were in accordance with the recommendations of the clinical practice guidelines, and it was used in combination therapy, especially with phosphodiesterase 5 inhibitors.
Urban socioeconomic variation influences the ecology and evolution of trophic interactions
Authors: Martin Ella , El‐Galmady Samer , Johnson Marc T. J. 
Published: March 2024

AbstractAs urbanization expands, it is becoming increasingly important to understand how anthropogenic activity is affecting ecological and evolutionary processes. Few studies have examined how human social patterns within cities can modify eco‐evolutionary dynamics. We tested how socioeconomic variation corresponds with changes in trophic interactions and natural selection on prey phenotypes using the classic interaction between goldenrod gall flies (Eurosta solidaginis) and their natural enemies: birds, beetles, and parasitoid wasps. We sampled galls from 84 sites across neighbourhoods with varying socioeconomic levels, and quantified the frequency of predation/parasitism on flies and natural selection by each enemy. We found that bird predation was higher in the highest income neighbourhoods, increasing the strength of selection for smaller galls. Wasp and beetle attack, but not their strength of selection, increased in lower income neighbourhoods. We show that socioeconomic variation in cities can have strong unintended consequences for the ecology and evolution of trophic interactions.
Managing bank liquidity hoarding during uncertain times: The role of board gender diversity
Authors: Davydov Denis , King Tatiana , Weill Laurent 
Published: March 2024

AbstractThis paper examines the effect of executive board gender diversity on the relationship between economic policy uncertainty (EPU) and bank liquidity hoarding (LH). We focus on the Russian banking sector, which, relative to most of the world, has a high share of women on bank executive boards. Using the news‐based EPU index developed by Baker, Bloom, and Davis (2016) and LH measures proposed by Berger, Guedhami, Kim, and Li (2022), we exploit a unique dataset from the Russian banking sector. While higher economic policy uncertainty tends to increase liquidity hoarding, we find that this effect diminishes as the gender diversity of the board increases. We attribute this finding to the moderating influence of gender diversity on stability and overreaction in decision‐making. Additionally, we find that the channel through which board gender diversity affects the impact of economic policy uncertainty on liquidity hoarding takes place via the hoarding of liquid assets. Our findings are robust to the use of alternative measures for economic policy uncertainty and gender diversity and hold after addressing endogeneity concerns. As women are still significantly under‐represented on bank boards in most countries, these results argue for policies to promote gender diversity on bank boards as a means of limiting the detrimental effects of economic policy uncertainty.
Prevention of dialysis disequilibrium syndrome in children with advanced uremia with a structured hemodialysis protocol: A quality improvement initiative study
Authors: Sethi Sidharth Kumar , Luyckx Valerie , Bunchman Timothy , Nair Aishwarya , Bansal Shyam Bihari , Pember Bryce , Soni Kritika , Savita  , Yadav Dinesh Kumar , Sharma Vivek , Alhasan Khalid , Raina Rupesh 
Published: March 2024

AbstractBackgroundDialysis disequilibrium syndrome (DDS) is a rare but significant concern in adult and pediatric patients undergoing dialysis initiation with advanced uremia or if done after an interval. It is imperative to gain insights into the epidemiological patterns, pathophysiological mechanisms, and preventive strategies aimed at averting the onset of this ailment.DesignProspective observational quality improvement initiative cohort study.Setting and ParticipantsA prospective single‐center study involving 50 pediatric patients under 18 years recently diagnosed with chronic kidney disease stage V with blood urea ≥200 mg/dL, admitted to our tertiary care center for dialysis initiation from January 2017 to October 2023.Quality Improvement PlanA standardized protocol was developed and followed for hemodialysis in pediatric patients with advanced uremia. This protocol included measures such as lower urea reduction ratios (targeted at 20%–30%) with shorter dialysis sessions and linear dialysate sodium profiling. Prophylactic administration of mannitol and 25% dextrose was also done to prevent the incidence of dialysis disequilibrium syndrome.MeasuresIncidence of dialysis disequilibrium syndrome and severe dialysis disequilibrium syndrome, mortality, urea reduction ratios (URRs), neurological outcome at discharge, and development of complications such as infection and hypotension. Long‐term outcomes were assessed at the 1‐year follow‐up including adherence to dialysis, renal transplantation, death, and loss to follow‐up.ResultsThe median serum creatinine and urea levels at presentation were 7.93 and 224 mg/dL, respectively. A total of 20% of patients had neurological symptoms attributable to advanced uremia at the time of presentation. The incidence of dialysis disequilibrium syndrome was 4% (n = 2) with severe dialysis disequilibrium syndrome only 2% (n = 1). Overall mortality was 8% (n = 4) but none of the deaths were attributed to dialysis disequilibrium syndrome. The mean urea reduction ratios for the first, second, and third dialysis sessions were 23.45%, 34.56%, and 33.50%, respectively. The patients with dialysis disequilibrium syndrome were discharged with normal neurological status. Long‐term outcomes showed 88% adherence to dialysis and 38% renal transplantation.LimitationsThis study is characterized by a single‐center design, nonrandomized approach, and limited sample size.ConclusionsOur structured protocol served as a framework for standardizing procedures contributing to low incidence rates of dialysis disequilibrium syndrome.
Chewing difficulties, oral health, and nutritional status in adults with intellectual disabilities: A cross‐sectional study
Authors: İslamoğlu Ayşe Hümeyra , Berkel Gülcan , Yildirim Hatice Selin , Aktaç Şule , Bayram Ferit , Sabuncular Güleren , Güneş Fatma Esra 
Published: March 2024

AbstractBackgroundChewing difficulty, poor oral health, inadequate and imbalanced nutrition are serious health problems in individuals with intellectual disabilities. The participants' chewing abilities, oral health and nutritional status were analysed in this study.MethodsForty‐five adult participants with intellectual disabilities were included. Anthropometric measurements, oral health assessments, chewing ability evaluations and dietary intake analyses were conducted.ResultsA 56.8% of the participants were classified as overweight or obese. Teeth grinding was reported in 33.3% of the participants, while 40.0% experienced drooling. All participants with Down syndrome and 58.6% of the participants with developmental delay had chewing difficulties. Inadequate nutrient intake was observed and the fibre, vitamins B1, B3, B9, sodium, phosphorus and iron intakes were significantly lower than reference values in those with chewing difficulty (p < .05).ConclusionsChewing difficulties were associated with lower intake of certain nutrients, highlighting the importance of addressing oral health and dietary counselling in this population.
Families on the space–time continuum: Conceptualizing and measuring temporal and spatial dimensions
Authors: Madhavan Sangeetha 
Published: March 2024

AbstractObjectiveIn this article, I propose a new approach to study the opportunities and challenges for low‐income families through a focus on two key dimensions of family life: time and space. I show how the interaction of these two dimensions produces a range of scenarios for different types of social support to emerge.BackgroundThe space–time continuum (STC) is a theoretical framework in physics that removes the distinction between time and space and, instead, treats them as part of a seamless continuum. Similar to its adaptation in psychology, I use it to develop a model of family dynamics to better understand the correlates of kinship support.MethodDrawing on data drawn from a longitudinal project in Nairobi, Kenya, the spatial dimension is operationalized as the proportion of kin who live in close proximity and the temporal pertains to the duration of time in which family members maintain particular arrangements. Multinomial logit regression models are used to analyze the relationship between STC exposure and the odds of having each type of support composition.ResultsThe receipt of specific types of support from kin does vary across the STC quadrants though not entirely consistent with expectations. Moreover, the role of non‐kin was found to be surprisingly low across all waves of data collection, underscoring the continued importance of kin‐based relationships.ConclusionThe space–time continuum approach offers a way to connect macro level factors such as labor market constraints to micro level adaptation, agency, change and continuity in family structure and function. In doing so, I also make a case for the critical role that research in the African context can play in the development of theory and methodological innovation in family sociology.
Identification, expression analysis, and functional verification of three opsin genes related to the phototactic behaviour of Ostrinia furnacalis
Authors: Huang Mei , Meng Jian‐Yu , Tang Xue , Shan Long‐Long , Yang Chang‐Li , Zhang Chang‐Yu 
Published: March 2024

AbstractOstrinia furnacalis is a disreputable herbivorous pest that poses a serious threat to corn crops. Phototaxis in nocturnal moths plays a crucial role in pest prediction and control. Insect opsins are the main component of insect visual system. However, the inherent molecular relationship between phototactic behaviour and vision of insects remains a mystery. Herein, three opsin genes were identified and cloned from O. furnacalis (OfLW, OfBL, and OfUV). Bioinformatics analysis revealed that all opsin genes had visual pigment (opsin) retinal binding sites and seven transmembrane domains. Opsin genes were distributed across different developmental stages and tissues, with the highest expression in adults and compound eyes. The photoperiod‐induced assay elucidated that the expression of three opsin genes in females were higher during daytime, while their expression in males tended to increase at night. Under the sustained darkness, the expression of opsin genes increased circularly, although the increasing amplitude in males was lower when compared with females. Furthermore, the expression of OfLW, OfBL, and OfUV was upregulated under green, blue, and ultraviolet light, respectively. The results of RNA interference showed that the knockout of opsin genes decreased the phototaxis efficiency of female and male moths to green, blue, and ultraviolet light. Our results reveal that opsin genes are involved in the phototactic behaviour of moths, providing a potential target gene for pest control and a basis for further investigation on the phototactic behaviour of Lepidoptera insects.
Seeking shade equity: Tree canopy coverage in public schools in Austin, TX
Authors: Williams Georgia E. , Diven Dayna G. 
Published: March 2024

AbstractBackground/ObjectivesTree canopies have dermatologic and environmental benefits, especially on school campuses. However, inequities likely exist, and tree planting initiatives may further exacerbate disparities. We sought to identify any relationship between tree canopy shade on public school campuses in Austin, TX and the socioeconomic makeup of the student population, as well as whether current initiatives appropriately address any inequities.MethodsIn this cross‐sectional study, we used ArcGIS, a publicly available geographic information system (GIS), to calculate the percentage of tree canopy on campuses within the Austin Independent School District (AISD) for the years 2006 and 2022. We compared this with the percentage of students eligible for free and reduced meals (FRM) at each school. The percentages of FRM‐eligible students were also compared for “low priority” versus “high priority” neighborhoods, as assigned by Austin's Tree Priority Map.ResultsAmong 112 schools analyzed, schools with minority FRM‐eligible students had significantly more tree canopy compared to schools with majority FRM‐eligible students (19.9% vs. 12.4%, p < .001). When comparing tree priorities, there was a significant difference between the percentage of FRM‐eligible students in “low priority” schools compared to “high priority” schools (23.8% vs. 62.2%, p < .001).ConclusionsAdditional work is needed to rectify inequities in tree canopy access for public school students. Designations such as those used in Austin's Tree Priority Map would likely help direct such efforts. We hope this study encourages future research with GIS by both dermatologists and other health care professionals to promote interdisciplinary work with urban planners.
The Brazilian diaspora: Intra‐community dynamics and differentiating factors among Brazilian migrants worldwide
Authors: Azeredo Rafael 
Published: March 2024

AbstractWhile the Brazilian diaspora scholarship is a vibrant literature that emerged in the 1980s and has gained prominence over the years, it remains geographically dispersed. Most studies focus on Brazilian migrants' experiences in a specific country or region of destination, and less attention has been paid to issues that influence the Brazilian diaspora transnationally. While the experiences of Brazilian migrants in different regions are varied and dependent on exogenous factors in the host society, this article reviews and discusses common markers of identity and positioning that shape intra‐community social dynamics between Brazilians who reside in different regions of the world. These ‘endogenous differentiating factors’ often produce tensions and intra‐community stratification, and may be carried from Brazil to the host community or produced in the host society. This article aims to integrate the geographically dispersed literature and emphasise commonalities experienced by Brazilians worldwide. It also argues that the focus on endogenous differentiating factors relates to a scholarly trend to frame the ‘Brazilian community’ as a heterogeneous entity with its own social dynamics rather than a homogenous ethnic group.
Effectiveness and family experiences of interventions promoting partnerships between families and pediatric and neonatal intensive care units: a mixed methods systematic review
Authors: Barnes Shannon , Macdonald Ibo , Rahmaty Zahra , de Goumoëns Véronique , Grandjean Chantal , Jaques Cécile , Ramelet Anne-Sylvie 
Published: March 2024

Objective:
The objective of this mixed methods review was to examine the effectiveness and family experiences of interventions promoting partnerships between families and the multidisciplinary health care team in pediatric and neonatal intensive care units.

Introduction:
Hospitalization of infants and children in neonatal intensive care units and pediatric intensive care units has a significant effect on their families, including increased stress, anxiety, and depression. Available evidence syntheses focused on specific family-centered care, but not on partnership, which is another aspect that may improve the families’ outcomes and experiences.

Inclusion criteria:
This review focused on effectiveness and experiences of interventions by health professionals in partnership with families of infants or children hospitalized in an intensive care unit. The type of intervention was a partnership between the health care team and the family, and focused on outcomes of stress, anxiety, depression, quality of life, attachment, or satisfaction with family-centered care.

Methods:
The JBI methodology for convergent segregated mixed methods systematic reviews was followed using the standardized JBI critical appraisal and data extraction tools. Ten databases were searched from January 2000 to April 2022. Findings of quantitative studies were statistically pooled through meta-analyses and those that could not pooled were reported in a narrative format. Qualitative studies were pooled through meta-synthesis.

Results:
This review included 6 qualitative and 42 quantitative studies. There was mixed methodological quality and all studies were included regardless of methodological quality. Meta-analyses showed positive improvements in anxiety, satisfaction with family-centered care, and stress, yet no conclusive effects in attachment and depression. These results should be interpreted with caution due to high heterogeneity. Qualitative analysis resulted in 2 synthesized findings: “Interventions that incorporate partnerships between families and the health care team can improve the family’s experience and capacity to care for the child” and “Having a child in intensive care can be an experience of significant impact for families” Integration of quantitative and qualitative evidence revealed some congruence between findings; however, the paucity of qualitative evidence minimized the depth of this integration.

Conclusions:
Partnership interventions can have a positive impact on parents of children in intensive care units, with improvements seen in stress, anxiety, and satisfaction with family-centered care.

Review registration:
PROSPERO CRD42019137834.
Absence of Monotony and Strain Effects on Referees’ Physical Performance During International Basketball Federation World Cup Basketball Competition
Authors: Paulauskas Rūtenis , Vaquera Alejandro , Figueira Bruno 
Published: March 2024

Purpose: The study aimed to conduct a comparative analysis of physical performance indicators and assess the levels of performance monotony and strain experienced by basketball referees. Methods: The study involved the participation of 12 basketball referees (mean age: 40.0 [4.9] y) affiliated with the International Basketball Federation. The investigation was carried out throughout 2 density tournaments, wherein the maximum heart rate, average heart rate, performance monotony, and performance strain were documented for 3 variables. Results: The findings indicated significant variations in the mean heart rate, maximum heart rate, total distance monotony, total distance strain, the total number of sprints monotony, the total number of sprints strain, calories monotony, and calories strain (P < .05). Decreasing the density of elite-level basketball competitions has been observed to reduce the monotony and strain experienced by referees. However, this action does not increase motion distance or speed zones. Conclusions: The environmental stressors experienced by senior-level athletes (World Cup) differ from those encountered by younger athletes (World Cup Under 19). Further investigation is required to ascertain the potential effects of competition monotony and strain on decision-making processes and the overall quality of refereeing.