bluuebunny/crossref_metadata_2025_split huggingface dataset:
“They helped me through the semester”: electronic instructor messages can foster the instructor-student relationship
Authors: Murray Courtney , Osterhage Jennifer 
Published: March 2024

ABSTRACT

Building rapport between instructors and students is a challenge, especially in large classes and in online environments. Previous work has shown that non-content Instructor Talk can foster positive student-teacher relationships, but less is known about non-content talk in electronic instructor messages. Here, we used the established Instructor Talk framework to craft positively phrased electronic messages that were sent through the course’s learning management system to students enrolled in an introductory biology course at a large public institution. We examined both close- and open-ended survey responses (
n
= 226) to assess students’ perceptions of the electronic messages, the course, and their instructor. Of the established Instructor Talk categories, the building student/instructor relationship category was most memorable to students. Encouragingly, 61% of students indicated they “liked the course more” and 88% indicated they “liked the instructor more” in response to the electronic messages. This demonstrates that implementing positively phrased Instructor Talk into electronic communication is an effective way to build rapport between instructors and students.
Anomaly Detection using Generative Adversarial Networks
Reviewing methodological progress and challenges
Authors: Lüer Fiete , Bohm Christian 
Published: March 2024

The applications of Generative Adversarial Networks (GANs) are just as diverse as their architectures, problem settings as well as challenges. A key area of research on GANs is anomaly detection where they are most often utilized when only the data of one class is readily available.
In this work, we organize, summarize and compare key concepts and challenges of anomaly detection based on GANs. Common problems which have to be investigated to progress the applicability of GANs are identified and discussed. This includes stability and time requirements during training as well as inference, the restriction of the latent space to produce solely data from the normal class distribution, contaminated training data as well as the composition of the resulting anomaly detection score. We discuss the problems using existing work as well as possible (partial) solutions, including related work from similar areas of research such as related generative models or novelty detection. Our findings are also relevant for a variety of closely related generative modeling approaches, such as autoencoders, and are of interest for areas of research tangent to anomaly detection such as image inpainting or image translation.
Patrimônio edificado e iluminação artificial externa: o caso do Convento da Penha, Vila Velha, Espírito Santo
Authors: Torres Rebeca Wright , Arcipreste Cláudia Maria , Aguiar Tito Flávio Rodrigues de 
Published: March 2024

Considerando a importância do projeto de iluminação nas intervenções em bens do patrimônio cultural edificado, este artigo busca compreender as premissas de projeto adotadas para a iluminação monumental de edificações e conjuntos arquitetônicos, bem como entender o papel da iluminação artificial na valorização e preservação dos mesmos. O objeto de estudo é o Convento da Penha, em Vila Velha, Espírito Santo, conjunto edificado a partir do século XVI, que teve um novo projeto de iluminação externa implementado em 2018. O trabalho baseou-se em estudo de caso, com coleta de dados por meio de análise documental, entrevistas com profissionais envolvidos no projeto e observações in loco. Foi possível compreender o processo da intervenção, analisando-o segundo três funções inerentes à preservação: a sustentabilidade, a comunicação e a valorização. A sustentabilidade das práticas projetuais aplicadas tem como premissa a conservação simbólica do monumento para a sociedade contemporânea sem comprometer a interpretação das futuras gerações, garantindo-se que estas terão a oportunidade de fazer sua própria leitura. A comunicação tem o papel de evidenciar as características principais do bem, guiando e facilitando a leitura do observador, ao refletir a história ali contada. A valorização é o resultado das funções anteriores, quando bem aplicadas, viabilizando o uso do edifício, fortalecendo o interesse da comunidade em sua utilização e manutenção. A partir da pesquisa realizada, apresentam-se diretrizes para futuros processos de projeto de iluminação artificial voltados para bens do patrimônio cultural edificado.
George McCready Price and Seventh-Day Adventism’s Influence on the Rise of Modern Creationism
Authors: Ruud Niq 
Published: March 2024

Abstract
Self-taught geologist and early convert to Seventh-day Adventism, George McCready Price played a significant, yet largely overlooked role in the rise of the modern creationist movement—and, to some degree, can be seen as the lynchpin leading to mainstream adoption of literal readings of the Christian scriptures. Influenced greatly by the writings of Ellen White, the prophetess of the Adventist movement, Price developed his ideas on flood geology which eventually became a cornerstone of creationist thinking. Price’s commitment to biblical literalism, influenced by White’s visions, shaped his worldview and led him to reconcile his interest in geology with the Adventist model of Earth’s history. His central argument for creationism was based on his belief in a worldwide flood, as described in the biblical narrative, which he saw as having shaped most of the Earth’s geological features. Although Price’s contributions were initially overlooked, his ideas gained prominence through the work of John Whitcomb and Henry Morris, who popularized his concepts in their influential book, The Genesis Flood. Price’s effect on modern creationism highlights the intersection of fundamentalist Christianity, particularly Adventism, with the evolving tension between theology and science in the 20th Century.
Structural equation modeling for identifying the drivers of health-related quality of life improvement experienced by patients with migraine receiving eptinezumab
Authors: Jönsson Linus , Awad Susanne F. , Regnier Stephane A. , Talon Brian , Kymes Steven , Lee Xin Ying , Goadsby Peter J. 
Published: March 2024

Abstract
Background
As new migraine therapies emerge, it is crucial for measures to capture the complexities of health-related quality of life (HRQoL) improvement beyond improvements in monthly migraine day (MMD) reduction. Investigations into the correlations between MMD reduction, symptom management, and HRQoL are lacking, particularly those that focus on improvements in canonical symptoms and improvement in patient-identified most-bothersome symptoms (PI-MBS), in patients treated with eptinezumab. This exploratory analysis identified efficacy measures mediating the effect of eptinezumab on HRQoL improvements in patients with migraine.

Methods
Data from the DELIVER study of patients with 2–4 prior preventive migraine treatment failures (NCT04418765) were inputted to two structural equation models describing sources of HRQoL improvement via Migraine-Specific Quality-of-Life Questionnaire (MSQ) scores. A single latent variable was defined to represent HRQoL and describe the sources of HRQoL in DELIVER. One model included all migraine symptoms while the second model included the PI-MBS as the only migraine symptom. Mediating variables capturing different aspects of efficacy included MMDs, other canonical symptoms, and PI-MBS.

Results
In the first model, reductions in MMDs and other canonical symptoms accounted for 35% (standardized effect size [SES] − 0.11) and 25% (SES − 0.08) of HRQoL improvement, respectively, with 41% (SES − 0.13) of improvement comprising “direct treatment effect,” i.e., unexplained by mediators. In the second model, substantial HRQoL improvement with eptinezumab (86%; SES − 0.26) is due to MMD reduction (17%; SES − 0.05) and change in PI-MBS (69%; SES − 0.21).

Conclusions
Improvements in HRQoL experienced by patients treated with eptinezumab can be substantially explained by its effect on migraine frequency and PI-MBS. Therefore, in addition to MMD reduction, healthcare providers should discuss PI-MBS improvements, since this may impact HRQoL. Health technology policymakers should consider implications of these findings in economic evaluation, as they point to alternative measurement of quality-adjusted life years to capture fully treatment benefits in cost-utility analyses.

Trial registration
ClinicalTrials.gov (Identifier: NCT04418765; EudraCT (Identifier: 2019–004497-25; URL: https://www.clinicaltrialsregister.eu/ctr-search/search?query=2019-004497-25).

Graphical Abstract
Comparison of integron mediated antimicrobial resistance in clinical isolates of Escherichia coli from urinary and bacteremic sources
Authors: Kumar Gauri , Balakrishna Keshava , Mukhopadhyay Chiranjay , Kalwaje Eshwara Vandana 
Published: March 2024

Abstract
Background
Antimicrobial resistance (AMR) is a global threat driven mainly by horizontal gene transfer (HGT) mechanisms through mobile genetic elements (MGEs) including integrons. The variable region (VR) of an integron can acquire or excise gene cassettes (GCs) that confer resistance to antibiotics based on the selection pressure. Escherichia coli plays a significant role in the genetic transfer of resistance determinants to other Gram-negative bacteria. Current study is aimed to detect and compare integron-mediated resistance in clinical isolates of E. coli. Unique isolates of E. coli from urine or blood cultures were studied for their antimicrobial resistance patterns and integrons were detected using polymerase chain reaction assays followed by Sanger sequencing of GCs.

Results
During the study period, a total of 470 E. coli isolates were obtained, 361 (76.8%) from urinary and 109 (23.1%) from bacteremic sources. Class 1 integrons were detected in 66 (18.2%) and 26 (23.8%) isolates respectively. Urinary isolates of E. coli harbouring Class 1 integrons demonstrated significantly higher rates of resistance (p < 0.05) for most antibiotics (12/16, 75%) compared to integron negative isolates. Although not statistically significant, similar differences were observed in bacteremic isolates. Among the urinary isolates, 27 (40.9%) had a VR, in which the most common GC array detected was DfrA17-AadA5 (n = 14), followed by DfrA5 (n = 4) and DfrA12 (n = 3). Among bacteremic isolates, only 4 (15.3%) had a VR, all of which were carrying DfrA17. The detected GC array correlated with the respective isolates’ phenotypic resistance patterns.

Conclusion
We found a strong correlation between integron positivity and trimethoprim resistance among E. coli from urinary sources. Although higher rates of resistance were observed in bacteremic isolates, they mostly carried empty integrons.
An examination of anxiety and its influence on health-related quality of life in Parkinson’s disease using the geriatric anxiety scale: a cross-sectional study
Authors: Heimrich Konstantin G. , Schönenberg Aline , Mendorf Sarah , Moussaoui Juliane , Prell Tino 
Published: March 2024

Abstract
Background
Anxiety is one of the most common but often overlooked mood-related nonmotor symptoms in people with Parkinson’s disease (PD). To improve the well-being of people with PD, it is important to understand the impact of anxiety in PD, especially its association with depressive and motor symptoms and its impact on health-related quality of life (HRQoL).

Methods
91 people with PD were assessed between June 2017 and June 2018. Anxiety was measured using the Geriatric Anxiety Scale (GAS) and its cognitive, somatic, and affective subscales. HRQoL was assessed using the Parkinson’s Disease Questionnaire 39 (PDQ-39). Moreover, sociodemographic information, depressive symptoms, cognition, motor and nonmotor symptoms were assessed. Descriptive statistics, regression analyses, and path analyses were performed to understand predictors of anxiety and its influence on HRQoL.

Results
Of the 91 people with PD, 35 (38.5%) experienced anxiety. Anxiety symptoms in these individuals primarily manifest as somatic sensations. Anxiety, motor, and depressive symptoms are interlinked but contribute individually to HRQoL. Beyond motor symptoms, cognitive and affective aspects of anxiety impact HRQoL. While anxiety and depression overlap, the somatic and cognitive aspects of anxiety play a significant role in determining HRQoL in addition to depressive symptoms.

Conclusion
Our study used the GAS and its three subscales to shed light on the connections between anxiety, depression, and motor impairment in people with PD. Although anxiety is linked to depression and motor symptoms, it independently affects the HRQoL of people with PD. Thus, it is crucial to adopt a comprehensive diagnostic approach that detects and considers the impact of anxiety on HRQoL in PD.
A survey of perceptions of exposure to new technology in residents and practicing ophthalmologists
Authors: Meer Elana , Davidson Krista , Ingenito Kristen Harmon , Brodie Frank , Schallhorn Julie M. 
Published: March 2024

Abstract
Background
Incorporation of the rapid advances in ophthalmologic surgical and diagnostic techniques inherent in the field poses a challenge to residency training programs. This study investigates exposure to new technologies during residency and perception of its impact on practice patterns.

Methods
Ophthalmology residents at various training levels and practicing ophthalmologists who had completed their training were invited to participate in a survey study assessing exposure to various technologies in residency and in practice. Data collection occurred from December 2022 to June 2023. Descriptive statistics were performed.

Results
The study received 132 unique responses, including 63 ophthalmology residents and 69 practicing ophthalmologists. 65.2% (n = 45) of practicing ophthalmologists and 47.6% (n = 30) of current residents reported discussion/training on newly developed products on the market (e.g. premium IOLS, MIGS), was “minimally discussed but not emphasized” or “not discussed at all” in residency. 55.1% (n = 38) of practicing ophthalmologists reported that exposure to new technologies during residency did influence types of technologies employed during practice. The majority resident physicians reported enjoying being trained on newer technology and feeling more prepared for future changes in the field (95.2%, n = 60) and felt that having industry partnerships in residency enhances education and training (90.5%, n = 57).

Conclusions
Considering how to maximize exposure to newer technologies/devices during residency training is important, and may contribute to training more confident, adaptable surgeons, who are more likely to critically consider new technologies and adopt promising ones into their future clinical practice.
Gender-specific pathways in mental health crisis in adolescents, from consultation to (in)voluntary admission: a retrospective study
Authors: Dil Linda , Mérelle Saskia , Lommerse Nick , Peen Jaap , So Pety , Van Rien , Zoeteman Jeroen , Dekker Jack 
Published: March 2024

Abstract
Background
A strong increase in mental health emergency consultations and admissions in youths has been reported in recent years. Although empirical evidence is lacking, gender differences in risk of admission may have contributed to this increase. A clearer understanding of the relationship, if any, between gender and various aspects of (in)voluntary care would help in more evidence-based service planning.

Methods
We analysed registry data for 2008–2017 on 3770 outpatient emergencies involving young people aged 12 to 18 years from one urban area in the Netherlands, served by outreaching psychiatric emergency services. These adolescents were seen in multiple locations and received a psychosocial assessment including a questionnaire on the severity of their problems and living conditions. Our aims were to (a) investigate the different locations, previous use of mental health service, DSM classifications, severity items, living conditions and family characteristics involved and (b) identify which of these characteristics in particular contribute to an increased risk of admission.

Results
In 3770 consultations (concerning 2670 individuals), more girls (58%) were seen than boys. Boys and girls presented mainly with relationship problems, followed by disruptive disorders and internalizing disorders. Diagnostic differences diminished in hospitalisation. More specifically, disruptive disorders were evenly distributed. Suicide risk was rated significantly higher in girls, danger to others significantly higher in boys. More girls than boys had recently been in mental health care prior to admission. Although boys and girls overall did not differ in the severity of their problems, female gender predicted admission more strongly. In both boys and girls severity of problems and lack of involvement of the family significantly predicted admission. Older age and danger to others significantly predicted admission among boys, whereas psychosis, suicidality and poor motivation for treatment predicted admission among girls.

Conclusion
There are different pathways for youth admission, which can partly be explained by different psychiatric classifications as well as gender-specific differences with regard to age, suicide risk, danger to others and the influence of motivation for treatment. Finally, for both genders, family desire for hospitalisation is also an important predictor.
Dietary diversity and its determinants among women of reproductive age residing in the urban area of Nouakchott, Mauritania
Authors: Issa Mariem Youssouf , Diagana Yacouba , Khalid EL Kari , Coulibaly Sidi Mohamed , Gueye Alioune , Dehah Rabab. M.H. , Vall Ould EL Kebir Mohamed 
Published: March 2024

AbstractBackgroundThe intake of nutrient-rich foods from diverse diets ensures adequate nutrition for women. This study aims to determine dietary diversity among women of reproductive age (WRA) using the MDD-W indicator and how it relates to their socio-economic characteristics in the city of Nouakchott, Mauritania.MethodsA community-based cross-sectional study was conducted on 240 women of reproductive age, aged 15–49 years. Food consumption data were obtained through unquantified 24 h recall which is designed to identify all foods consumed by the women during this period. We computed MDD-W as the consumption of at least five out of ten predefined food groups according to the guideline of the Food and Agriculture Organization (FAO) of the United Nations. In order to determine which factors had a statistically significant influence on dietary diversity among women, we used a value ofP < 0.05.ResultsThe mean of dietary diversity was 5.48 and 71.7% of WRA had an acceptable minimum dietary diversity. During the study period, 96.25% and 80% of women consumed vitamin A and iron-rich foods respectively. The consumption rate of starchy foods, vitamin A-rich fruits and vegetables, meat, fish and chicken, milk and dairy products, dark green leafy vegetables and finally other vegetables was higher; 99.6%, 75.3%, 80%, 62.5%, 60.4% and 83.3% respectively. On the other hand, the consumption of legumes, eggs and other fruits was low; at 21.7%, 14.2% and 13.8% respectively.ConclusionsThe study showed that more than half of the studied population had an acceptable minimum dietary diversity. The diet was mainly based on the consumption of starchy foods, meat and other vegetables than those rich in vitamin A.
One-year trajectories of nutritional status in perimenopausal women: a community-based multi-centered prospective study
Authors: Liao Shujuan , Zhao Li , Huang Chuanya , Xiong Anqi , Xiong Weijun , He Yirong , Huang Xiao , Hunter Victoria , Luo Biru 
Published: March 2024

Abstract
Background
Nutritional status is a modifiable factor associated with perimenopausal women’s health and quality of life. Assessing body composition indicators helps to comprehensively understand nutritional status compared with using body mass index (BMI) only. However, few published studies measured the trends in body composition among perimenopausal women.

Objectives
To assess the one-year trajectory of the nutritional status of perimenopausal women and to explore its influential factors.

Methods
A community-based observational study with 3-wave repeated measurements at 6-month intervals was carried out. The nutritional status indicators include weight, body mass index (BMI), and body composition variables. Bioelectrical impedance analysis was used to assess body composition. Repeated measures ANOVA and Chi-square test were used to calculate the changes in nutritional status and generalized estimating equations were performed to explore their influential factors.

Results
2760 participants completed the study. Increasing trajectories in weight (from 56.05 ± 7.55 to 57.02 ± 7.60), fat mass (from 17.99 ± 4.80 to 20.49 ± 4.90), and waist-hip ratio (from 0.86 ± 0.04 to 0.91 ± 0.15) were found (P < 0.001). Decreasing trajectories in skeletal muscle (from 20.30 ± 2.38 to 19.19 ± 2.46), protein level (from 7.39 ± 0.79 to 7.06 ± 0.81), and total body water (from 27.87 ± 2.92 to 27.00 ± 3.01) were found (P < 0.001). Being married/unmarried with a partner and without negative life events were associated with higher total body water, skeletal muscle, and protein level, while negatively associated with fat mass and waist-hip ratio. Age was positively associated with fat mass (P < 0.001). Participants with junior high school education were prone to increased fat mass (P = 0.018) compared with those holding primary school education and below. A per capita monthly income of 1500 to 3000 Yuan was associated with higher total body water, skeletal muscle, and protein level (P < 0.001) compared with a per capita monthly income of less than 1500 Yuan.

Conclusion
Worsening nutritional status exists in perimenopausal women, which is characterized by increased weight, fat mass, and waist-hip ratio, and decreased skeletal muscle, total body water, and protein level. For greater efficiency, precision nutritional interventions are needed, and recipients should be classified into different risk levels based on their sociodemographic background.