bluuebunny/crossref_metadata_2025_split huggingface dataset:
Design of a drag-free control system for gravity field measurement satellite based on a cusped hall electric propulsion system
Authors: Cui Kai , Zheng Jialin , Xu Kai , Wang Hao , Chen Jing , Niu Xiang 
Published: March 2024

Abstract
To obtain a more accurate gravity field model, gravity field measurement satellites use the drag-free control system to minimize the residual disturbance force of the satellite and improve the measurement accuracy of the gravity field. To meet the drag-free control accuracy, these tasks propose the requirements of wide continuous throttling ability, low noise, and rapid response for the propulsion system, which acts as the actuator of the control system. This research takes a cusped hall electric propulsion system as the research object and constructs a component-level propulsion system model based on experimental data. The drag-free control system design and simulation are conducted with the theory of orbital dynamics, atmospheric drag model, and control method based on the extended state observer. The simulation results show that the slow thrust response speed of the propulsion system limits the bandwidth of the control system, resulting in the control accuracy not meeting the mission requirements. To solve this problem, a thrust response speed optimization method based on coordinated control of input parameters of the propulsion system is proposed. The results show that the thrust response speed is improved and the bandwidth of the control system is increased after the coordinated control of the flow rate and the voltage, which makes the residual accelerations of the satellite meet the drag-free control requirements of the gravity field measurement satellite.
Fluctuation trend of inflammatory indexes related to gestational diabetes mellitus from second trimester to third trimester of pregnancy
Authors: Mingming Xu , Linlin Tang , Yaping Wang 
Published: March 2024

Abstract
Objective: to explore the changes of serum inflammatory bodies (NLRP3), interleukin-1 receptor antagonist (IL-1Ra) and thioredoxin binding protein-2 (TBP-2) in pregnant women at 24 and 36 weeks of pregnancy and their correlation with gestational diabetes mellitus (GDM) and neonatal weight.
Materials and methods: in this study, 65 pregnant women with gestational diabetes who were diagnosed with gestational diabetes mellitus in our hospital from December 2022 to June 2023 were randomly selected as GDM group, and 65 pregnant women without gestational diabetes mellitus at the same gestational week were selected as normal group (nude 65). The pregnancy information and serum samples of pregnant women at 24 and 36 weeks of gestation were collected. The levels of NLRP3, IL-1Ra and TBP-2 were measured by enzyme linked immunosorbent assay (ELISA) to explore their changes during pregnancy. The changes of NLRP3, IL-1Ra and TBP-2 at 24 and 36 weeks of pregnancy in GDM pregnant women and their correlation with GDM were analyzed.
Results: in the general data, pre-pregnancy BMI, neonatal weight, gestational hypertension and macrosomia were associated with gestational diabetes mellitus, and the difference was statistically significant. Statistical analysis showed that there was no significant change in NLRP3, IL-1Ra and TBP-2 in normal group, but in GDM group, the expression level of IL-1Ra increased, while the expression level of NLRP3 and TBP-2 decreased in serum samples at 24 and 36 weeks of pregnancy, but the changes of NLRP3, IL-1Ra and TBP-2 were positively correlated with each other at 36 weeks of gestation. The levels of NLRP3, IL-1Ra and TBP-2 in pregnant women in normal group were lower than those in GDM group, and the birth weight of newborns increased with the increase of NLRP3 and TBP-2 and decreased with IL-1Ra. The results of multivariate logistic regression analysis showed that NLRP3 was an independent influencing factor of GDM. The ROC curve analysis of GDM predicted by NLRP3 at 24 weeks of pregnancy showed that NLRP3 had good predictive value for GDM (AUC=0.720,95%CI was 0.630-0.809), and the combination of NLRP3, IL-1Ra and TBP-2 also had good predictive value for GDM.
Conclusion: the changes of NLRP3, IL-1Ra and TBP-2 run through the 24 and 36 weeks of pregnancy, so they play an important role in predicting gestational diabetes mellitus and neonatal weight.
COPB2 promotes hepatocellular carcinoma progression through regulation of YAP1 nuclear translocation
Authors: Wu Biao , Wu Yumeng , Liu Yifei , Chen Hongjian , Zhao Wenjing , Liu Jibin , Zhang Xiubing , Xu Jian , Wang Yilang , Guo Xianlin , Chen Xudong , Zhang Suqing 
Published: March 2024

Abstract
The Hippo pathway has been shown to be upregulated in many cancer patients. Yes-associated protein 1 (YAP1), an oncogene and core factor of the Hippo pathway, plays a key role in tumorigenesis and progression. Although YAP1 is a vital oncogene in HCC progression, its nuclear localization prevents its consideration as a potential therapeutic target. Recently, studies have reported that COPB2 also plays a critical role in HCC development, but its mechanism of action is unclear. Here, we found that COPB2 affects the drug sensitivity of HCC cells to DDP by regulating YAP1 nuclear translocation and stability. More importantly, COPB2 combined with YAP1 expression was related to overall postoperative survival in HCC patients and was an independent prognostic factor. The established nomogram and artificial neural network models also highlighted the prognostic value of these two genes for HCC patients. In summary, our findings suggest that COPB2/YAP1 affects the drug sensitivity of HCC cells to DDP and that targeting COPB2/YAP1 may be a promising strategy for the precision treatment of HCC.
Cultivars and method of application influences the effect of silicon on incidence and damage of phloem feeders, induction of defense reaction, attraction of natural enemies and yield in black gram (Vigna mungo L.)
Authors: Saw Gouranga , Nagabovanalli Prakash , Jeer Mallikarjuna , R.K Murali-Baskaran 
Published: March 2024

Abstract
Silicon, a quasi-essential nutrient element, is well known for imparting tolerance to various biotic and abiotic stresses in crops. The present studies were carried out to evaluate the effect of silicon with two methods of application viz., soil drenching and foliar application against phloem feeders under field conditions for two seasons on two different black gram cultivars. Among the cultivars, Vikral responded better to silicon treatment (orthosilicic acid) than Pratap Urd 1 with reference to in reduction of population of phloem feeders and enhancement of defence enzyme activity, silicon uptake, total sugars and total phenols and yield in both the seasons. Among the application methods, soil drenching (2 mLL− 1 of OSA) proved to be the superior method of administration to record significantly low population of phloem feeders, increased activity of defence enzymes and total sugars, total phenols content, improved activity of coccinellids and yield in both the seasons. However, it holds good with foliar application (2 mLL− 1 of OSA) method. Both silicon application methods of OSA were significantly superior than insecticidal check and untreated control treatments. Deposition of Si was the highest in the leaves of black gram (1.541%) when OSA was administered through soil than foliar (1.451%) and untreated control (0.891% endogenously available Si). Highest benefit: cost ratio recorded in soil drenching of OSA @ 2 mLL− 1 (1.88 and 1.93) surpassed BC ratio of recommended insecticidal check (1.65 and 1.72) during winter and summer seasons, respectively. Both the application methods of OSA proved significantly superior over insecticidal check with respect to management of phloem feeders in black gram including enhanced grain yield, coccinellids activity and induced biochemical defence as well as lowest cost of cultivation, which can be easily incorporated with other practices for eco-friendly, sustainable management of phloem feeders in black gram.
The influence of neutral MDP-Na salt on dentin bond performance and remineralization potential of etch-&amp;-rinse adhesive
Authors: Li Mingxing , Zheng Haiyan , Xu Yuedan , Qiu Yuan , Wang Yinlin , Jin Xiaoting , Zhang Zhengyi , Zhang Ling , Fu Baiping 
Published: March 2024

Abstract

Objectives.
To investigate the effect of neutral 10-methacryloyloxydecyl dihydrogen phosphate (MDP)-Na salt on the dentin bond strength and remineralization potential of etch-&-rinse adhesive.
Methods.
Two experimental etch-&-rinse adhesives were prepared by integrating varying weight percentages (0wt%, 20wt%) of neutral MDP-Na into a base primer. A commercial etch-&-rinse adhesive Adper Single Bond 2 (SB, 3M ESPE) was used as control. Following this, microtensile bond strength (MTBS) was evaluated after subjecting the samples to 24 h of water storage or a 6-month incubation in artificial saliva. Fourier-transformed infrared spectrometry was used for assessment of the degree of conversion of the experimental adhesives and the adsorption properties of MDP-Na on the dentin organic matrix. Furthermore, the efficacy of neutral MDP-Na in facilitating the remineralization of two-dimensional collagen fibrils and the adhesive–dentin interface was investigated using transmission electron microscopy and selected-area electron diffraction.
Results.
The addition of MDP-Na into the primer increased both the short- and long-term MTBS of the experimental adhesives (p = 0.000). No difference was noted in the degree of conversion between the control, 0 wt% and 20 wt% MDP-Na-containing groups (p = 0.336). The intra- and extra-fibrillar remineralization of the two-dimensional collagen fibril and dentin bond hybrid layer was confirmed by transmission electron microscopy and selected-area electron diffraction when the primer was added with MDP-Na.
Conclusions.
The use of neutral MDP-Na results in high-quality hybrid layer that increase the dentin bond strength of etch-&-rinse adhesive and provides the adhesive with remineralizing capability. This approach may represent a suitable bonding strategy for improving the dentin bond strength and durability of etch-&-rinse adhesive.
Acceptance of Virtual Patients as a Continuous Professional Development Approach among Practicing Nurses in Primary Health Care Settings in a Low-Income Country: A quasi-experimental study
Authors: Nyiringango Gerard , Fors Uno , Tumusiime David K , Forsberg Elenita 
Published: March 2024

Abstract
Background: Virtual patients are an educational technological approach used in healthcare education. Its distinctive features have rendered virtual patient technology appealing for the training of medical and healthcare students, particularly in the enhancement of clinical reasoning. Virtual patients are less often applied for continuous professional development for practicing healthcare providers, and there is a scarcity of studies exploring this possibility. This study aimed to assess the acceptability of nurses for using virtual patients as a continuous professional development approach.
Method: The study used a quasi-experimental design. The study was conducted in ten primary healthcare settings in Rwanda. Among 76 nurses who consented to participate in the study, 56 completed the intervention and responded to the study questionnaire. Following a one-week program of continuous professional development on four non-communicable diseases, the study used a self-administered questionnaire based on the Technology Acceptance Model 3 to collect data. Descriptive statistics including median, minimum, and maximum were used as the major analysis of participants' responses. The study also used a correlation test to assess the relationship of variables.
Results: Across all items in the questionnaire, the median response tended towards either agree or strongly agree, with only a minority number of participants expressing strong disagreement, disagreement, or neutrality. The results indicated a significant positive correlation between perceived usefulness and behavior intention (p<0.001).
Conclusion: The findings indicate an acceptability and behavioral intention of adopting virtual patients as an alternative continuous professional development approach among nurses working at health centers in Rwanda or other locations with similar contexts.
Ultrasound - assisted synthesized multi-phase copper vanadate (Cu 3 V 2 O 8 /Cu 2 V 2 O 7 /Cu 0.4 V 2 O 5 ) shape-controlled nanoparticles as electrode material for energy storage applications
Authors: Gowrisankar G. , Mariappan R. , Palani E. , Krishnamoorthy E. 
Published: March 2024

Abstract
In this novel study, complex phases of copper vanadium oxides, including Cu3V2O8, Cu2V2O7, and Cu0.4V2O5, were synthesized using an ultrasound-assisted co-precipitation technique and evaluated as suitable electrodes for energy storage devices that exhibit pseudo-capacitive behavior.The structural properties investigation of CuV, CuV + 0.3%PVP and CuV + 3%PVP nanoparticles at 400 oC. The XRD patterns confirm monoclinic crystal system with multi-phase nature of copper vanadate’s further morphology have been optimized with stabilizing and shape-directing agent Polyvinylpyrrolidone (CuV + 0.3%PVP and CuV + 3%PVP) only at elevated temperature 400℃. The electrochemical behavior of CuV + 0.3%PVP and CuV + 3%PVP were observed under cyclic voltammetry (CV),Galvanostatic charge and discharge (GCD) and Electronic impedance spectroscopy (EIS). Most significantly, the shape-controlled copper vanadate nanoparticles (CuV + 3%PVP) exhibited exceptional electrochemical performance, demonstrating a notable specific capacitance increased significantly23.2% improvement. The specific capacitances of CuV and CuV + 3%PVP nanoparticles are 211.09 F/g 260.4 F/g respectively, an impressive energy density of 107.25 Wh/kg and power density of 297.9W/kg at 0.5 A/g. Thus, copper-vanadate materials may be observed as capable short time e high voltage electrode for pseudo capacitor applications.
Porous carbon nanosheets from coal tar pitch for zinc ion hybrid capacitor
Authors: Wei Feng , Liu Qingyun , Zhang Jiadong , Ren Ziquan , Zhang Linlin 
Published: March 2024

Abstract

As a by-product of coal chemical industry, it is very suitable to be used as carbon precursor to prepare carbon materials because of its rich aromatic hydrocarbons. However, the preparation of carbon materials often uses a lot of metal oxides and strong alkali, which will not only cause corrosion to the equipment, but also produce wastewater. Herein, the mixture of bicarbonate and hydrogen oxalate was used as template and activator to synthesize porous carbon nanosheets, which presents high specific surface area of 784.8 m2 g− 1 and multiple ion transport channels. Due to those merits, the PCNS2 cathode displays superior zinc ion storage performance, such as high specific capacity of 210.1 F g− 1, excellent energy density and power output of 83.3 Wh kg− 1 and 17.2 kW kg− 1 and long cycle life with capacity retention of 98.57% after 11000 cycles. This work provides an avenue to prepare porous carbon nanosheets for energy storage devices.
Effects of dietary Bacillus velezensis LSG2-5 on digestion, intestinal morphology, microflora, and related gene expression in Rhynchocypris lagowskii Dybowski
Authors: Li Shao-hua , Zhang Yu-rou , Lin Li-li , Zhang Dong-ming , Zhang Tian-yi , Zhu Wen-li , Jiang Dan , Li Yuxin , Wang Sibu , Wang Xin , Wang Qiu-ju , Chen Yu-ke 
Published: March 2024

Abstract
The study was to investigate at how Bacillus velezensis LSG2-5 from the host intestine affected the
digestive function, intestinal morphology, intestinal microflora, and expression expression of tight junction protein genes in Rhynchocypris lagowskii Dybowski. Different doses of B. velezensis LSG2-5 were added to diets, namely control (0 CFU/g), B-6 (106 CFU/g), B-7 (107 CFU/g), B-8 (108 CFU/g) and B-9 (109 CFU/g) groups. Fish (mean weight: 9.98 ± 0.05 g) were fed for 56 days. The trypsin, lipase, amylase, γ-glutamyltransferase, Na+-K+-ATPase, and alkaline phosphatase activity in the liver and intestines of the treatment groups considerably increased in comparison to the control group (p<0.05), according to the results. Contrasted with the control group, the muscle layer thickness, lamina propria width, intestinal fold height, and fold breadth of the B-7, B-8, and B-9 groups increased considerably (p<0.05). Intestinal ZO-1, Claudin-3, and APN mRNA expression levels displayed significant up-regulation trends (p<0.05). The profusion of Proteobacteria, Bacteroidetes, Fusobacteria, and Cyanobacteria in intestines first increased and then decreased. In contrast, the abundance of Firmicutes showed an opposite trend. In summary, adding 107~109 CFU/g of B. velezensis LSG2-5 to feed can improve the intestinal health of R. lagowskii Dybowski.
A predictive model of symptoms for pain in independently living frail older people in palliative care
Authors: Veen Suzan van , Drenth Hans , Hobbelen Hans , Krijnen Wim , de Graaf Everlien , Finnema Evelyn 
Published: March 2024

Abstract
Background: Pain assessment is a necessary step in pain management in older people in palliative care. In older people, pain assessment can be challenging due to underreporting and atypical pain manifestations by other distressing symptoms. Anxiety, fatigue, loss of appetite, insomnia, dyspnoea, and bowel problems correlate with pain in palliative care patients. Insight into these symptoms as predictors may help to identify the underlying presence of pain. This study aimed to develop a prediction model for pain in independently living frail older people in palliative care.
Methods: In this cross-sectional observational study, community-care nurses from multiple organizations across the Netherlands included eligible patients (life expectancy < 1 year, aged 65+, independently living and frail). The outcome pain and symptoms were assessed by means of the Utrecht Symptom Diary. Also, demographic and illness information, including relevant covariates age, sex and living situation, was collected. Multivariable logistic regression and minimum Akaike Information Criterion(AIC) were used for model development and Receiver Operating Characteristics(ROC)-analysis for model performance. Additionally, predicted probability of pain are given for groups differing in age and sex.
Results: A total of 157 patients were included. The final model consisted of insomnia(Odds Ratio[OR]=2.13, 95% Confidence Interval[CI]=1.013-1.300), fatigue(OR=3.47, 95% CI=1.107-1.431), sex(female)(OR=3.83, 95% CI=2.111-9.806) and age(OR=-1.59, 95% CI=0.922-1.008) as predicting variables. There is an overall decreasing trend for age, older persons suffer less from pain and females have a higher probability of experiencing pain. Model performance was indicated as fair with a sensitivity of 0.74(95% CI=0.64-0.83) and a positive predictive value of 0.80(95% CI=0.70-0.88).
Conclusion: Insomnia and fatigue are predicting symptoms for pain, especially in women and younger patients. The use of a symptom diary in primary care can support the identification of pain.
Application of Electrochemical Methods to Assess the Stability and Investigation of Factors Influencing the Ancient Copper-Arsenic Artefacts from 3rd Millennium BC
Authors: Bakhshandehfard Hamidreza , Pourzaghan Vahid , Emami Mohammadamin 
Published: March 2024

Abstract

The Bazman district constitutes one of the four districts of Iranshahr City in the Sistan and Baluchistan province of Iran. This study examines the conduct of arsenic copper alloys in chloride environments. Electrochemical methods were used to investigate the corrosion rate of 5As alloys and ancient alloys from Spidej Bazman. Tafel plots (LSV) were used to determine corrosion rate, corrosion current density, and CV method for oxidation conditions. Different percentages of the alloy showed different corrosion rates. The behavior of chlorides on the corrosion of these alloys was investigated via soil solution sampling of Spidej Bazman at pH 10.85 with both manufactured and ancient alloys. Four types of corrosion morphology were identified in the arsenic bronze works of this site. These alloys' corrosion mechanism was investigated, and Type (I) corrosion was observed. To test corrosion behavior, the linear sweep voltammetry (LSV) technique was employed. Electrochemical testing using line scan voltammetry demonstrated that the rise in chloride promotion efficiency led to greater migration of the arsenic element from the alloy. Corrosion morphology evident in artefacts unearthed from this site suggests persistent corrosion and bronze disease.
Study of the Magnetocaloric Effect and Critical Behavior in Double Perovskite Manganese Oxides Pr 1.5 A 0.5 Mn 2 O 6 (A=Mg, Ba)
Authors: Yun Huiqin , Li Ze , Jin Xiang , Zhao Jianjun , Liu Jingshun 
Published: March 2024

Abstract
In this study, polycrystalline samples of Pr2Mn2O6 (parent phase) and Pr1.5A0.5Mn2O6 (A = Mg, Ba) were prepared using the high-temperature solid-phase reaction method. The effects of Mg and Ba doping on magnetocaloric properties and critical behavior of the parent phase were systematically investigated. Under a magnetic field of 7 T, the relative cooling power (RCP) values for this sample series were approximately 483.46 J·kg− 1, 428.22 J·kg− 1, and 479.88 J·kg− 1, respectively. The critical behavior analysis revealed that the parent phase showed short-range exchange interactions, while Pr1.5A0.5Mn2O6 (A = Mg, Ba) exhibited long-range exchange interactions. The temperature dependence of the order parameter n was studied under different magnetic fields, confirming the phase transition types and validating the accuracy of the critical exponents obtained. The research findings suggest that both the parent phase and Ba-doped ceramics at the A-site hold promise as magnetic refrigeration materials.
Robert's uterus with adenomyosis: A case report and review of the literature
Authors: Rao Yangyang , Chen Min , LI Yiju 
Published: March 2024

Abstract

Purpose To provide the differential diagnosis and determine the treatment of Robert's uterus with adenomyosis, a rare uterine malformation.
Methods A patient who had Robert’s uterus with adenomyosis was admitted to our hospital in December 2022; we analyzed and summarized her case.
Results Ourpatient complained of progressively worsening primary dysmenorrhea over 3 years and lower abdominal pain lasting for 2 days. Her level of carbohydrate antigens 125 (CA125) was 372.10 U/mL. Examinations in several hospitals indicated that she had a single-horned uterus as well as a residual horned uterus. In our hospital, we found the malformation described by Robert. This was corrected by open abdominal surgery as follows:During the procedure, pelvic adhesions were first isolated, then the closed uterine cavity and adenomyosis were resected. Subsequently, the left ovarian endometriosis cyst was resected, and right tubal ligation was performed. After surgery, three injections of gonadotropin-releasing hormone A (GnRH-A) were given, which lowered the patient’s CA125 to 14 U/mL and normalized her condition.
Conclusion In this work, wepioneered a new therapeutic approach for the treatment of Robert's uterus with adenomyosis andprovide a valuable reference for clinical practice.