bluuebunny/crossref_metadata_2025_split huggingface dataset:
Therapeutic efficacy of LysGH15 against necrotising pneumonia caused by Staphylococcus aureus in a rabbit model
Authors: Zhang Bowei , Song Liran , Wang Yongran , Zhang Meimei , Chen Chong , Ning Hui , Wang Li , Qiu Cao , Wang Xinwu , Sun Changjiang , Feng Xin , Han Wenyu , Wang Bin , Ji Yalu , Gu Jingmin 
Published: February 2025

IntroductionStaphylococcus aureus (S. aureus) is one of the most important zoonotic pathogens and can be transmitted to humans through the meat diet routes, causing necrotising pneumonia.MethodsThis study investigated the therapeutic effect of bacteriophage lysin LysGH15 on necrotising pneumonia in rabbit model caused by S. aureus.ResultsIn the in vitro experiments, 50 μg/mL LysGH15 not only significantly reduced the viable count (approximately 3.24 × 106 CFU/g) of chicken meat stored at 4°C for 48 h but also effectively reduced the viable count of chicken meat thawed at 4°C and 30°C, with reductions of approximately 1.42 × 106 CFU/g and 2.78 × 106 CFU/g, respectively. In the in vivo experiments, a single intranasal administration of 300 μg/rabbit increased the survival rate of rabbits to 60%. At 72 h postinfection, the number of bacteria in the lung tissues of the rabbits treated with LysGH15 was 7 × 104 CFU/g, which was significantly lower than that in the lung tissues of rabbits treated with PBS (7.76 × 106 CFU/g) or linezolid (6.38 × 105 CFU/g). In addition, LysGH15 treatment alleviated lung tissue damage in infected rabbits and significantly reduced the levels of Panton-Valentine leukocidin (PVL), alpha-toxin (Hla), and the cytokines IFN-γ, TNF-α, and IL-8 in their lung tissues, similar to those in rabbits treated with linezolid.DiscussionThese results suggest that LysGH15 has the potential to be used as a novel antimicrobial agent for the treatment of necrotising pneumonia caused by S. aureus.
RANCANG BANGUN SISTEM INFORMASI PENJUALAN PADA TOKO ANISA MENGGUNAKAN PHP NATIVE
Authors: Fatih Ahmad 
Published: February 2025

The purpose of this study is to design and build a web-based sales information system for Anisa Store using PHP Native. The purpose of this system is to overcome problems that often occur due to manual recording of sales transactions, which causes errors and inefficiencies. This system displays real-time sales and cash flow reports and allows management of product, customer, and supplier data. The rapid application development (RAD) method allows iterative development through prototyping and testing in stages. The results of system testing show that this system can speed up the transaction process, reduce recording errors, and improve sales management efficiency at Anisa Store. It is hoped that the implementation of this system will greatly assist Anisa Store's business operations and become a model for the development of similar systems in the future.

ABSTRAK

Tujuan dari penelitian ini adalah untuk merancang dan membangun sistem penjualan informasi berbasis web untuk Toko Anisa yang menggunakan PHP Native. Tujuan dari sistem ini adalah untuk mengatasi masalah yang sering terjadi karena pencatatan transaksi penjualan secara manual, yang menyebabkan kesalahan dan inefisiensi. Sistem ini menampilkan laporan penjualan dan arus kas secara real-time dan memungkinkan pengelolaan data produk, pelanggan, dan pemasok. Metode pengembangan aplikasi cepat (RAD) memungkinkan pengembangan berulang melalui pembuatan prototipe dan pengujian secara bertahap. Hasil pengujian sistem menunjukkan bahwa sistem ini dapat mempercepat proses transaksi, mengurangi kesalahan pencatatan, dan meningkatkan efisiensi manajemen penjualan di Toko Anisa. Diharapkan bahwa penerapan sistem ini akan sangat membantu operasi bisnis Toko Anisa dan menjadi model untuk pengembangan sistem serupa di masa depan.
PERANCANGAN DAN IMPLEMENTASI WEBSITE MENGUNAKAN PLUGIN ELEMENTOR SEBAGAI MEDIA PROMOSI PT. MINIFROZ BERDIKARI RETAILINDO INDONESIA
Authors: Muladi Muhamad 
Published: February 2025

Small and Medium Enterprises are one of the important players in a country's economy. Therefore, an effective promotional media is needed so that smes can compete with big businesses. One of the promotional media that can be used is a website using wordpress CMS. Using a content management system (CMS) and the wordpress Elementor Plugin as the leading application for creating a company profile website is very easy to implement. Create a website using the tools provided by the Elementor Plugin. So Users just change the layout according to the website design what Wordpress CMS and Elementor Plugin do is a perfect combination to make a company profile page. Where is CMS Wordpress, the features already exist to make it easier for an Administrator to process or create a website.

Abstrak

Usaha Kecil dan Menengah merupakan salah satu pemain penting dalam perekonomia suatu negara. Oleh kareta itu, dibutuhkan media promosi yang efektif agar UKM dapat bersaing dengan bisnis besar. Salah satu media promosi yang dapat digunakan adalah website mengunakan CMS Wordpress. Menggunakan sistem manajemen konten (CMS) dan Plugin WordPress Elementor sebagai aplikasi terdepan untuk membuat website profil perusahaan sangat mudah diimplementasikan. Membuat situs web menggunakan alat yang disediakan oleh Plugin Elementor. Jadi Pengguna hanya mengubah tata letak sesuai dengan desain situs web apa yang dilakukan CMS Wordpress dan Plugin Elementor merupakan kombinasi sempurna membuat halaman profil perusahaan. Di mana CMS Wordpress Fitur- fiturnya sudah ada untuk memudahkan seseorang Administrator dalam mengolah atau pembuatan website.
Pengaruh Regulasi Hukum Terhadap Inovasi Produk dan Layanan Perusahaan
Authors: Anugrah Dikha , Lintang Dialog Bias , Akhmaddhian Suwari 
Published: February 2025

Inovasi produk dan layanan merupakan kunci bagi perusahaan untuk mencapai keunggulan kompetitif dan bertahan dalam pasar yang dinamis. Regulasi hukum memainkan peran penting dalam mendorong atau menghambat inovasi. Penelitian ini bertujuan untuk menganalisis pengaruh regulasi hukum terhadap inovasi produk dan layanan perusahaan di Indonesia. Penelitian ini menggunakan pendekatan kualitatif dengan studi kasus pada 10 perusahaan di Indonesia yang memiliki tingkat inovasi tinggi. Data dikumpulkan melalui wawancara mendalam dengan para pemimpin perusahaan dan karyawan yang terlibat dalam proses inovasi. Data dianalisis dengan menggunakan teknik grounded theory untuk membangun teori yang menjelaskan bagaimana regulasi hukum mempengaruhi inovasi.
Hasil penelitian menunjukkan bahwa regulasi hukum memiliki pengaruh positif terhadap inovasi produk dan layanan perusahaan. Regulasi yang dirancang dengan baik dapat menciptakan lingkungan yang kondusif bagi perusahaan untuk berinovasi dengan memberikan kepastian hukum, meningkatkan akses ke sumber daya, dan mendorong kolaborasi. Penelitian ini memberikan kontribusi yang signifikan terhadap pemahaman tentang bagaimana regulasi hukum dapat digunakan untuk mendorong inovasi di Indonesia. Hasil penelitian ini dapat membantu pemerintah dalam merancang regulasi hukum yang efektif untuk mendorong inovasi dan membantu perusahaan dalam beradaptasi dengan regulasi hukum yang baru untuk meningkatkan inovasi.
Kata Kunci: Regulasi Hukum, Inovasi Produk dan Layanan, Perusahaan, Indonesia
Kolonisasi Lifeworld: Telaah Teori Kritis Jürgen Habermas atas Kerusakan Lingkungan di Bima Nusa Tenggara Barat
Authors: Ardiansyah Irfan , Hardinandar Fajrin , Ridwan  , Firmanto Taufik 
Published: February 2025

Penelitian ini bertujuan untuk menganalisis secara filosofis penyebab kerusakan lingkungan dengan menggunakan kacamata teori kritis Jürgen Habermas dan hubungan kolonisasi lifeworld oleh sistem dengan transformasi ekonomi politik yang berdampak pada kerusakan lingkungan di Kabupaten Bima. Metode penelitian menggunakan pendekatan filosofis dan normatif-empiris. Temuan kami menunjukkan bahwa, kerusakan lingkungan disebabkan upaya pemerintah meningkatkan produksi pertanian, khususnya jagung. Program PUAP, PNPM, UPSUS, GRATIEKS mendorong perluasan lahan, mengakibatkan perambahan hutan. Peraturan Pemerintah Nomor 23 Tahun 2021 Tentang Penyelenggaraan Kehutanan dan Peraturan Menteri Nomor 8 Tahun 2021 tentang Perizinan Berusaha Pengelolaan Hutan (PBPH) dibuat untuk memberikan batasan terhadap pemanfaatan hutan, namun secara paradoksal memungkinkan perambahan hutan untuk proyek strategis Nasional dan pemulihan ekonomi. Akhirnya, kami menemukan korespondensi yang kuat antara Teori Habermas, di mana sistem kapitalistik-libertarian telah mengkolonisasi dunia kehidupan (lifeworld) masyarakat Kabupaten Bima untuk merambah hutan dan menyebabkan kerusakan lingkungan.
Accurate measurement of lattice constants and thermal expansion coefficients of halide perovskite alloy CH3NH3Pb(Br1−xClx)3
Authors: Watanabe Yoshiaki , Shibayama Naoyuki , Jitsukata Tomoki , Hori Akiko , Sotome Masato , Matsushita Tomonori , Kondo Takashi 
Published: February 2025

Abstract
We accurately determined the lattice constants a and the thermal expansion coefficients α
L of the mixed-halide perovskite CH3NH3Pb(Br1−x
Cl
x
)3 as functions of the Cl−-composition x. We used single-crystalline samples and performed X-ray photoelectron spectroscopy for the determination of x, and single-crystal X-ray diffraction for the determination of a. We found that mixed-halide single crystals were significantly Cl−-rich compared to the precursor solutions from which single crystals were grown. The obtained Cl−-composition-dependent lattice constant a(x) well follows the Vegard’s law:

a
(
x
)
=

a

0

(
1
−
x
)
+

a

1

x

, where

a
0

=
5.9366
±
0.0028

Å

,

a
1

=
5.6866
±
0.0027

Å

. In addition, from the temperature dependence of a(x), we determined the thermal expansion coefficients α
L(x) of the mixed-halide perovskite CH3NH3Pb(Br1−x
Cl
x
)3 for the first time.
Opportunities for using green technologies to assess the effectiveness of green innovations in Russian industry
Authors: Sivkova A. I. 
Published: February 2025

Aim. The work aimed to develop a rating map of Russian regions by the level of development of green technologies, as well as determine the potential for using individual quantitative indicators in models for assessing the effectiveness of green innovations in industry.Objectives. The work considers approaches to defining the concept of “green technologies”, analyzes the indicators of the development of green technologies in individual industries and regions of the country.Methods. The author used literature analysis, rating maps, correlation analysis, and Granger testing to solve the problems.Results. In 2020–2023, 48% of the analyzed regions of Russia showed an extremely low implementation of green technologies. The most unfavorable situation is registered in nine entities with either no companies developing the technologies or the technologies used. The manufacturing industries have become the leaders in the development and application of green technologies. A mutual cause-and-effect relationship was revealed between such indicators as volume of waste generated and amount of used green technologies for reducing harmful emissions, as well as amount of recycled waste and number of waste processing technologies used.Conclusions. There is a strong relationship between the volume of recycled waste and the number of green technologies used. It is advisable to include the application of quantitative indicators of the development of green technologies in the models for assessing the effectiveness of green innovations in industry. Further research in the field of the effectiveness of the implementation of principles of the green economy should include the study of the correlation between the formalization of the sustainable development strategy with the number of used technologies for reducing air pollution and the amount of carbon dioxide emissions by industrial enterprises.
Pelatihan Pemanfaatan Reference Management Software Zotero Untuk Mendukung Pengelolaan Dokumen Ilmiah Mahasiswa
Authors: Ahmar Dewi Satria , Magfirah  , Tri Santoso  , Sri Hastuti Virgianti Pulukadang  , Muhammad Fath Azzajjad  , Ayu Rahayu  , Edi Ilimu  , Agus Nasir  , Ahmar Ansari Saleh 
Published: February 2025

Kegiatan pengabdian kepada masyarakat (PkM) ini dilaksanakan pada Program Studi S-1 Pendidikan Kimia, Universitas Sembilanbelas November kolaka. Kegiatan PkM dilaksanakkan dengan mempertimbangkan hasil analisis situasi dan kebutuhan mahasiswa akan pemanfaatan reference management software Zotero untuk mendukung pengelolaan dokumen ilmiah mahasiswa. Pelatihan memiliki langkah-langkah: perencanaan, pelaksanaan dan evaluasi. Metode yang digunakan pada pelatihan adalah diskusi, Latihan/praktek dan simulasi melalui online learning. Peserta pelatihan terdiri dari 34 orang mahasiswa. Luaran yang diperoleh adalah 100% peserta telah mengetahui reference Management Software dalam pengelolaan dokumen ilmiah, 85.29% peserta telah mampu mengoperasikan reference management software Zotero dan 94.12 % peserta telah memiliki apllikasi reference management software Zotero.
Optimalisasi Bank Sampah Digital Tim PPK Ormawa HIMA Manajemen UPGRIS di Desa Plalangan
Authors: Firdaus Nada Nisrina , Puspitasari Ratih Hesty Utami , Abdika Mohammad Festin , Rahmad Moh. Adib Nur , Adrianto Syahrul , Putra Edo Cahya 
Published: February 2025

Pemberdayaan merupakan suatu konsep untuk memberikan tanggungjawab yang lebih besar kepada orang-orang tentang bagaimana melakukan pekerjaan. Pemberdayaan akan berhasil jika dilakukan oleh pengusaha, pemimpin dan kelompok yang dilakukan secara terstruktur dengan membangun budaya kerja yang baik. Konsep pemberdayaan terkait dengan pengertian pembangunan masyatakat dan pembangunan yang bertumpu pada masyarakat. Desa Plalangan merupakan sebuah desa yang berada di Kecamatan Gunung Pati, Kota Semarang, yang mempunyai potensi cukup besar di bidang peternakan, pertanian, serta perikianan. Luas kelurahan ini mencapai ± 331.727 Ha/m2. Desa ini memiliki penduduk yang berjumlah 4.354 jiwa (Februari 2023). Kepadatan penduduk di desa ini menimbulkan beberapa dampak positif maupun negatif yang muncul. Dampak positif dari adanya kepadatan penduduk di desa ini adalah tersedianya banyak tenaga kerja, peluang usaha lebih besar, dan meningkatnya produksi industri rumah tangga. Sedangkan dampak negatif dari adanya kepadatan penduduk menjadi permasalahan diantaranya adalah munculnya pemukiman dan sekitar bank sampah terlihat kumuh, sampah rumah tangga meningkat, serta kesadaran penduduk untuk membuang sampah pada tempatnya menurun Ormawa Himpunan Mahasiswa (HIMA) Manajemen yang terdiri dari mahasiswa Manajemen dan Teknik Informatika telah melakukan survei dan pertemuan dengan kepala desa, perangkat desa, serta mitra. Beberapa kegiatan yang akan dilakukan adalah membuat solusi dari permasalahan yang timbul adalah penanganan yang tepat dengan penerapan dan optimalisasi Zero Waste Lifestyle bagi para penduduk desa, dengan program tersebut harapannya mampu untuk menjembatani setiap rumah tangga mengelola sampahnya secara tertib dan teratur untuk disalurkan dalam satu tempat yang terhubung dalam satu sistem atau perangkat. Hasil kegiatan dalam Pengabdian ini adalah Aplikasi Bank Sampah Digital yang bisa dimanfaatkan oelh masyarakat Desa Plalangan dan dilakukan sosialisasi secara menyeluruh untuk masyarakat.
Pendampingan Penguatan Manajemen Kelompok Tani dan Website pada Petani Kakao Desa Tegal Maja Lombok Utara
Authors: Kuntary Ibrahim Isra Dewi , Apriani Apriani , Arzani Lalu Danu Prima , Martiningsih Ni Gst Ag Gde Eka , Sumantra I Ketut 
Published: February 2025

Kabupaten Lombok Utara (KLU) merupakan satu-satunya daerah tertinggal saat ini di Provinsi Nusa Tenggara Barat. Wilayah Desa Tegal Maja terletak di Kecamatan Tanjung Kabupaten Lombok Utara memiliki potensi yang melimpah terdiri dari potensi alam, sumber daya manusia, kelembagaan dan potensi sarana dan prasarana. Sebagian besar penduduk desa Tegal Maja memiliki mata pencaharian sebagai petani dilihat dari pemanfaatan lahan yang ada. Adapun permasalahan yang dihadapi Kelompok Tani Mitra 1 dan 2 (Patuh Tujuan II dan Buana Karya) yaitu sebagai berikut : Para petani memasarkan kakaonya masih secara konvensional, para petani belum memanfaatkan kelembagaan melalui kelompok tani secara tepat. Sehingga solusinya adalah memberikan pelatihan manajemen kelompok tani untuk penguatan organisasi kelompok tani serta keberlangsungan usaha, Memberikan bimbingan teknis pemasaran produk kakao berbasis Badan Usaha Milik Desa (Bumdes), website desa dan media social, Menjalin kerjasama antar kelompok tani, perangkat desa, pengepul sehingga tercipta sistem pemasaran biji kakao yang saling menguntungkan. Adapun indikator Pencapaian Keberhasilan dalam menerapkan pemasaran modern mencakup tingkat partisipasi petani dalam pelatihan, penggunaan aktif platform digital untuk promosi produk, peningkatan volume penjualan biji kakao melalui platform tersebut, dan hasil survei kepuasan petani dan stakeholder tentang efektivitas pemasaran modern. Kelompok tani terlihat sangat aktif dan partisipatif dari jumlah orang yang menjawab pertanyaan pada soal dengan benar pada saat sebelum melakukan pelatihan dan setelah melakukan pelatihan terlihat jumlah petani yang sudah paham lebih banyak dibanding sebelumnya baik mengenai data pengguna internet, isi UU system informasi desa, masalah yang sedang dihadapi dan solusi yang perlu dilakukan.
Documentation of the Salivary Gland Tumors: An Institutional Data From Turkey
Authors: Kucuk Ulku , Akoz Gamze , Cakır Ebru , Pala Emel , Bayol Umit , Gumussoy Murat , Cukurova Ibrahim 
Published: February 2025

Objective: World-wide series show some differences in the incidence and clinicopathologic features of salivary gland tumors.
Methods: A total of 248 cases of SGTs diagnosed in our hospital between 1998 and2013 were reviewed with respect to their clinicopathologic features.
Results: There were 128 male and 116 female patients with a mean age of 49.2. Of these 248 tumors 214 were benign and 34 were malignant. The mean age of the patients with benign tumors was 48.6 years and with malignancies was 55.3 years. The most common site was the parotid gland (83.5%) followed by submandibular and minor ones. Pleomorphic adenoma (50.4%) was the most common benign tumor and affected female patients more frequently. It is followed by Warthin’s tumor that favored parotid gland. Adenoid cystic carcinoma was the most frequent malignant tumor followed by mucoepidemid carcinoma and carcinoma ex pleomorphic adenoma and the majorities were located in the submandibular gland.
Conclusion: In the present study, epidemiological data was compared with other worldwide series. Our retrospective study revealed that; benign tumors were more frequent, major salivary glands were more affected by both benign and malignant tumors than minor salivary glands and the parotid gland was the most affected site. Epidemiological data in the various parts of the world can be helpful for a better understanding of SGT's biology and characteristics.
Tumor Mimicking Bladder Endometriosis
Authors: Kucuk Ulku , Pala Emel , Pala Halil Gursoy , Cakir Ebru , Divrik Rauf Taner 
Published: February 2025

Endometriosis is described as the presence of endometrial tissue outside the uterine corpus. Though urinary tract endometriosis is uncommon, the bladder is the most common localization amongst them. Here we present three cases admitted to our hospital with similar complaints such as dysuria and abdominal pain. All of the patients had previous cesarean section history. And radiological examination of the bladder revealed solid masses located on the bladder wall. One of the case additionally had a protruding, polipoid luminal mass. Two of the cases were treated with transurethral resection and one with partial cystectomy. We noted similar histological findings such as endometrial stroma and glands within the smooth muscle fibers. The stromal components were positive with CD10, epithelial components were positive with both estrogen and progesterone receptor immunohistochemically.
As a result bladder endometriosis should be kept in mind in the differential diagnosis of mass forming urinary tract lesions.
Kikuchi-fujimoto disease: histopathological and clinical review of a case
Authors: Pehlivan Belma , Karagoz Muammer , Belli Seyda , Tokat Fatma , Saglican Yesim 
Published: February 2025

Kikuchi-Fujimoto disease (KFD) or histiocytic necrotizing lymphadenitis is an idiopathic, benign, self-limited, rare disease. This disease is mostly encountered in Asia and in young adult. Cervical lymph node involvement is the most common symptom. In addition, fever, fatigue, increase in erythrocyte sedimentation rate, and leukocytopenia may also occur. A specific diagnosis and treatment for this disease has not been defined. The diagnosis of this disease however can be diagnosed with excision of lymph node and histopathological examination. KFD can often resolve spontaneously. If there is no spontaneous regression, oral corticosteroid therapy can be applied. In this case report, we were referred a rare case of Kikuchi-Fujimoto disease, presented with the cervical lymphadenopathy, increased erythrocyte sedimentation rate, and fever.
Unilateral Ureterocele Presenting With Multiple Stones In An Old Lady: Endoscopic Incision and Stone Extraction
Authors: Yuksel Mehmet 
Published: February 2025

In this video supported case report, we aimed to present our step-by-step technique of endoscopic incision of ureterocele and stone extraction in a 66 years old female patient with a large ureretocele containing multiple urinary stones. The patient was with the complaints of flank pain and disuria. The patient was prepared under spinal anesthesia and positioned in lithotomy position. Under direct visualisation of cystoscopic view, the ureterocele and other ureteral orifice of the duplicated urinary system have been detected. A ureteral catheter was placed into the other ureter for safety. Subsequently, a transverse endoscopic incision was performed by using a 26 F standard resectoscope with an electrical loop of TUIP at the inferior lateral border, and an artificial secondary ureteral orifice has been created. Though this new orifice, the resectoscope was inserted into the ureter, and multiple ureteral stones were seen inside the ureterocele and dilated ureter. These stones were extracted by using stone forceps and directly irrigation and decompression of the ureteral lumen. No stone fragmentation was required in this operation. After the elimination of all of the stones, a 4.8 F DJ stent was inserted into the ureter and the procedure has been completed without any complication. At the postoperative follow up period, no complication was occurred and all of the complaints were improved.
Relationship Between HDLc, NonHDLc/ HDLc Ratio and Gilbert's Syndrome
Authors: Ozenc Salim , Sarlak Hakan , Iscen Sinan 
Published: February 2025

Objective: We investigated the relationship between HDL-cholesterol levels that is indirect marker of ApoA-I production in liver, Non-HDL-cholesterol that is indirect marker of ApoB and GS
Methods: HDLc, NonHDLc/ HDLc Ratio levels were investigated in subjects with GS (n=148) and compared to healthy controls (n=148).
Results: Age and BMI distributions were similar between the two groups. HDLc levels were lower in GS than the healthy controls (p=0.012). However, TC, Non-HDLc, Non-HDLc/HDLc levels were higher in GS than the healthy controls (p=0.002, p=0.001, p<0.001, respectively). In correlation analysis, UB were negatively mildly correlated with HDLc (r=−0.191, p=0.001) and positively correlated with TC (r=0.436, p<0.001), Non-HDLc (r=0.511, p<0.001) and Non-HDLc/HDLc (r=0.512, p<0.001) in the whole group.
Conclusions: The contrary of previously studies, we would like to suggest that bilirubin is a only antioxidant agent that protects from cardiovascular disease, but not physiological hypolipidemic agent.