bluuebunny/crossref_metadata_2025_split huggingface dataset:
Rebuilding Publicity: A Cultural Path to Building a Community of Rural Social Governance
Authors: Hu Yingchu 
Published: March 2024

How to build a rural social governance community through the path of rural culture? This article takes the funeral reform policy of S County in southern Anhui as an example to analyze how funeral, a rural public cultural activity, constructs a rural social governance community from the perspective of public reconstruction. Funeral, as a public activity within the village, provides a public space as a field carrier for participation. In this space, public authority maintains order, public resources provide material support, public actions inject vitality, and rural public culture is reaffirmed and strengthened in this process, thus forming a good public order and public spirit. By utilizing the virtual public space provided by modern media, the reputation control mechanism has once again strengthened the value norms and practical norms of rural areas, further spreading the public spirit and order formed within the village. This article suggests that in the formulation and implementation of policy practice, attention should be paid to the power and importance of cultural traditions and localized knowledge, and a reasonable institutional supply should be designed to form a social governance pattern of co construction, co governance, and sharing.
PENGARUH INTERVENSI DINI BERBASIS KELUARGA TERHADAP PERKEMBANGAN ANAK DENGAN DOWNSYNDROME
Authors: Nurhidayah Nisa 
Published: March 2024

Kehadiran anak ditengah keluarga merupakan sesutu yang didambakan dan dinantikan, namun pada kenyataannya tidak semua anak terlahir sesuai dengan apa yang diinginkan. Ketika apa yang dinantikan bertolak belakang dengan apa yang diinginkan biasanya dapat menimbulkan ketidakpuasan bahkan tidak sedikit yang menjadi depresi. Hadirnya anak berkebutuhan khusus, dalam penelitian ini yaitu anak dengan downsyndrome, ditengah-tengah keluarga dapat menjadi problematika tersendiri yang tidak bisa dihindarkan. Berdasarkan banyaknya kasus orang tua yang mengalami kesulitan dalam menghadapi anak downsyndrome, maka penelitian ini bertujuan untuk membantu orang tua untuk dapat mengenal, memahami, dan menangani anak mereka sendiri di rumah dengan optimal. Penelitian ini menerapkan metode intervensi dini berbasis keluarga, dimana keluarga berperan banyak dalam penanganan anak karena merupakan inti terpenting dalam pemberian layanan pada anak. Hasil penelitian ini secara signifikan menunjukkan perubahan tidak hanya pada perkembangan kemampuan anak tetapi juga pada sikap orang tua terhadap penanganan anak mereka. Orang tua menjadi lebih terbuka wawasannya tidak hanya dalam pengetahuan tetapi juga dalam keterampilan penanganan anak dengan downsyndrome.
METODE BERMAIN PERAN UNTUK MENINGKATKAN KEMAMPUAN BERBAHASA PADA ANAK KELOMPOK A DI RA NURUR RABIAH KOTA TASIKMALAYA
Authors: Rusmiati Iyus , Mumung Asep , Nurfitri Tetin 
Published: March 2024

Penelitian ini dilatar belakangi oleh masih banyaknya anak yang mengalami kesulitan dalam kemampuan berbicara berdasarkan hasil pencapaian perkembangan bahasa yang berada pada kategori belum berkembang dan mulai berkembang. Sehingga diperlukan inovasi dalam metode pembelajaran yang mampu meningkatkan kemampuan berbicara pada anak kelompok A di RA Nurur Rabiah. Penelitian ini bertujuan untuk mengetahui pengaruh metode bermain peran terhadap kemampuan berbahasa pada anak kelompok A di RA Nurur Rabiah. Penelitian ini tergolong quasi experiment dengan rancangan post-test only control group design. Populasi penelitian adalah anak kelompok A di RA Nurur Rabiah. Sampel penelitian ini adalah 14 anak kelompok A sebagai kelompok eksperimen, dan 14 anak kelompok A1 sebagai kelompok kontrol Data penelitian tentang kemampuan berbicara. Hasil menunjukkan terdapat pengaruh yang signifikan metode bermain peran (terhadap kemampuan berbicara pada anak kelompok A di RA Nurur Rabiah.
THE CORELATION OF PARENTS USING THERAPEUTIC COMMUNICATION WITH THE LENGTH OF TIME USING GADGETS IN A DAY 24 HOURS IN EARLY CHILHOOD (3-8 YEARS OLD) IN CIANTRA VILLAGE PEACOCK ALLEY IX 2022
Authors: Utami Sri , Nurti Y.K. Gea  , Baltasar S. S. Dedu  
Published: March 2024

The flow of globalization that cannot be separated from human life at this time which greatly affects daily life, one of which is communication. Communication is the provision of infomation, news, or interaction carried out by two or more people in the hope that there will be feedback given after listening to the information. The communication tool that can be used in this case is using therapeutic communication. Therapeutic communication can not only be done by nurses but parents to see the lenght of time using gadgets that occur in children. Gadgets is a telecomunications medium taht has ad small form that is easy to carry and is widely used today. This is clear evidence of the development of science and tacholog (science technology) at this time, gadgets are able to influence humans both in terms of mindset and behavior. The study aims to determine”The Corelation Of Parents Using Therapeutic Communication With The Length Of Time Using Gadgets In A Day 24 Hours In Early Chilhood (3-8 Years Old) In Ciantra Village Peacock Alley IX 2022”. The type of quantitative research with cross sectional method. The population is parents who have an early age of 3-8 years with a total of 34 respondents. Sampling techique using total sampling. The result obtained with a significannt level of 95% of a value of 5% (0,05) obtained p value (0,005) < value (0,05) so taht it can be concluded from these results that H0 is rejected, meaning that there is a The Corelation Of Parents Using Therapeutic Communication With The Length Of Time Using Gadgets In A Day 24 Hours In Early Chilhood (3-8 Years Old) In Ciantra Village Peacock Alley IX 2022. There is a The Corelation Of Parents Using Therapeutic Communication With The Length Of Time Using Gadgets In A Day 24 Hours In Early Chilhood (3-8 Years Old) In Ciantra Village Peacock Alley IX 2022.
Pengaruh Manajemen Kurikulum dan Kompetensi Ustaz Terhadap Prestasi Belajar Santri pada Era Milenial di Pondok Pesantren Darul Muqomah Pangandaran
Authors: Masud Masud 
Published: March 2024

This study aims to (1) determine the effect of curriculum management on student achievement in Islamic boarding schools at Darul Muqomah Pangandaran, (2) determine the effect of Ustadz competence on student achievement in Darul Muqomah Pangandaran Islamic Boarding School (3) Determine the effect of curriculum management and Ustadz competence on achievement. students study at the Darul Muqomah Islamic Boarding School in Pangandaran.
In this study the authors used quantitative descriptive and verification with the type of correlational research. Data were collected through questionnaires from respondents with a population of all teachers (30 teachers) at the Darul Muqomah Islamic Boarding School, Pangandaran. Researchers conducted validity and reliability tests, as well as multiple linear regression through the SPSS windows 24 program.
Based on the results of the analysis of research data, that: Islamic boarding school curriculum management, ustadz competence and student learning achievement at the Darul Muqomah Islamic Boarding School, Pangandaran are good. The management of the pesantren curriculum and the competence of the ustadz simultaneously affect the learning achievement of students at the Darul Muqomah Islamic Boarding School in Pangandaran, this is evidenced by the multiple linear regression equation model with a significance value of 0.000 < 0.05, Ho is rejected and Ha is accepted.
Pengendalian Wireless Terpusat Dengan Capsman Dalam Mewujudkan Quality Of Service Jaringan Wireless
Authors: Riski Efriandana  
Published: March 2024

Access point merupakan perangkat yang biasa digunakan dalam jaringan wireless (Hotspot area) dimana user atau pengguna terhubung ke internet menggunakan media udara melalui perangkat pendukung yang disebut Access point. Akan tetapi dengan penempatan koneksi dari Hostpot wireless yang tidak relevan akan menybabakan terjadi nya gangguan dari layanan dan kualitas dari jaringan wireless itu sendiri yang mengakibatkan penuruanan dari QoS(Quality of Service). Setiap Access point akan diatur dan dikonfigurasi satu persatu, dan tentunya ini akan menjadi masalah ketika jumlah Access point sudah banyak tentunya hal ini akan memerlukan waktu yang lama dan kurang efektif, mengatasi masalah tersebut pada perangkat Access point akan menghasilkan ssid yang tentunya akan mempengaruhi interferensi sinyal dan penggunaan pita frekuensi. Dengan adanya banyak Access point yang terpasang di area tersebut akan menyulitkan bagi administrator dalam mengkonfigurasi setiap Access point. Maka muncul teknik untuk mengatasi permasalahan tersebut dengan menggunakan fitur Capsman (Controller Access Point System Manager). Hal ini menjadi solusi dalam manajemen jaringan yang mampu mengatur seluruh Access point tersebut dalam satu kendali secara terpusat di jaringan wireless. Maka dengan begitu kita dapat Menerapkan parameter QoS (Quality of Service) yang bertujuan untuk mengetahui kinerja jaringan wireless. Sehingga dengan menerapkan parameter QoS (Quality of Service) Maka Administrator telah memperoleh dari hasil pengujian baik di sisi troughput, delay, jitter, dan packet loss untuk nilai rata-rata dari hasil yang diperoleh. yaitu dengan kategori : Sangat bagus, Bagus, Sedang dan Buruk.
Penerapan Customer Relationship Management Pada Sistem Informasi Berbasis Web Wedding Organizer
Authors: Harahap Edho Rahmat , Delianti Vera Irma 
Published: March 2024

Syariah Wedding Organizer adalah sebuah usaha jasa yang bergerak di bidang pelayanan jasa penyewaan perlengkapan pernikahan yang memiliki banyak pelanggan. Syariah Wedding Organizer ini memiliki strategi yang baik dalam menghadapi persaingan bisnis yang cukup ketat serta lebih mengedepankan pelanggan (customer oriented) dari pada keuntungan semata (profit oriented). Peneliti melakukan penelitian pada jasa penyewaan perlengkapan pernikahan pada Syariah Wedding Organizer, pada pengamatan awal yang peneliti lakukan Syariah Wedding Organizer masih menggunakan sistem secara manual untuk melakukan pendataan customer dan juga pelayanan serta strategi promosi untuk menarik perhatian pelanggan. Masalah lainnya yang peneliti temukan adalah kurang berkembangnya Syariah Wedding Organizer disebabkan oleh sistem pelayanan seperti pada proses pelayanan pelanggan tidak adanya fasilitas yang membantu pelanggan untuk menyampaikan saran, kritik, dan pertanyaan mengenai produk serta tidak adanya fasilitas yang membantu pelanggan untuk mendapatkan informasi pelayanan seperti adanya promo dan adanya diskon. Perancangan CRM menggunakan bahasa Pemrogram PHP dan database MySQL. Hasil penelitian ini adalah implementasi CRM berbasis web yang dapat membantu Syariah Wedding Organizer mempromosikan produk dan jasa layanannya kepada pelanggan lama dan baru serta membantu mempermudah pelanggan berkomunikasi dan melakukan order produk dan layanan Syariah Wedding Organizer.
Pelatihan Pemanfaatan Media Pembelajaran Berbasis Kebutuhan Siswa Bagi Guru TK Nurul Muslimin
Authors: Putra Eka , Supiyandi  , Amin Muhammad 
Published: March 2024

Program pengabdian masyarakat yang bertajuk “Pelatihan Pemanfaatan Media Pembelajaran Berbasis Kebutuhan Siswa Bagi Guru TK Nurul Muslimin” ini bertujuan untuk meningkatkan kemampuan guru dalam mengembangkan media pembelajaran yang sesuai dengan kebutuhan siswa. Kegiatan ini melibatkan mitra yaitu para guru dan siswa TK Nurul Muslimin. Kegiatan ini menggunakan metode pelatihan. Kegiatan diawali dengan kunjungan awal untuk menganalisis situasi dan kebutuhan para guru di lokasi. Dari hasil kunjungan tersebut disepakati bahwa kegiatan ini difokuskan pada peningkatan kemampuan guru dalam mengembangkan media pembelajaran sesuai kebutuhan siswa. Kegiatan ini dilaksanakan sebanyak empat kali pertemuan. Pemantauan dan penilaian untuk menindaklanjuti hasil kegiatan PKM dilakukan pada akhir kegiatan. Hasil penelitian menunjukkan bahwa setelah melalui kegiatan pengabdian kepada masyarakat guru mampu memahami dan mengimplementasikan teori dan teknik pengembangan media pembelajaran berdasarkan kebutuhan siswa.
Extracts of Trichilia heudelotii (Meliaceae) Planch, a Nigerian Medicinal Plant have Antibacterial and Antifungal Activity
Authors: Adeniyi, B. A.  , Adagbasa, O. O.  , Idowu, P. A.  , Igbokwe, C. O.  , Moody, J. O.  , Aiyelaagbe, O. O.  
Published: March 2024

There is no overemphasizing the need for novel phytotherapeutic agents to combat the menace of drug resistance in microbial pathogens. Many plant species so far, have yielded some bioactive compounds with great promise for such drugs. Trichilia heudelotii (Meliaceae) is commonly used in traditional medicine in Nigeria for the treatment of many microbial infections ranging from gastrointestinal infections to gonorrhea. This study is thus designed to determine the phytochemicals present in T. heudeloti and evaluate the plant’s extracts' antimicrobial activity on some bacterial and fungal isolates.
The phytochemical screening was done using standard procedures. Soxhlet extracts using n-hexane and methanol were drying in vacuo. The methanol extract was partitioned into petroleum ether, chloroform, and aqueous fractions. The antibacterial and antifungal activity of the extracts determined using the agar-well diffusion method. The MICs were determined for the extracts using the agar dilution method.
The qualitative phytochemical screening revealed the presence of tannins, saponins, alkaloids, cardenolides, and anthraquinones in the leaf, stem bark, and root bark of T. heudelotii. The extracts showed considerable activity against Gram-positive and Gram-negative organisms, and fungi with dermatophytes including Klebsiella spp, Escherichia coli, Proteus spp, Pseudomonas aeruginosa, Staphylococcus aureus, Bacillus subtilis, Neisseria gonorrhoeae, Mycobacterium smegmatis, Candida albicans, Aspergillus niger, Rhizopus stolonifer, Penicillium spp, Microsporium canis, and Trichophyton mentagrophytes. The mean diameter of zones of inhibition exhibited by the extracts ranged between 10mm+ 0.5 and 32+ 0.33mm. The methanol extracts compared favourably with the gentamycin (standard control). The minimum inhibitory concentration (MIC) ranged between 0.157mg/mL and 20mg/mL. The crude methanol extracts and methanol residue showed the highest activity of all the extracts while the hexane extract showed the lowest activity and the Petroleum ether fraction was inactive.
These results showed the potential of T. heudelotii as a possible candidate for bioactive compounds for the discovery and development of new drugs for the treatment of diseases caused by test pathogens.
Neuronal Nicotinic Receptors: One Hundred Years of Progress
Authors: Kellar Kenneth J. , Xiao Yingxian 
Published: March 2007

AbstractNeuronal nicotinic cholinergic receptors mediate the actions of acetylcholine in ganglia and the CNS. These receptors are pentameric proteins formed from combinations of 12 different subunits. Thus, this family of receptors consists of multiple subtypes defined by their subunit composition. All of the receptors are ligand‐gated cation channels that pass sodium, potassium and calcium, but the different subtypes have different biophysical and pharmacological characteristics. These receptors are located on the axons of catecholamine, GABA, acetylcholine and glutamate neurons, so they can influence a large number of diverse functions in the nervous system. In addition to mediating the essential actions of endogenous acetylcholine, these receptors are the primary target of nicotine, the addictive agent in tobacco. Thus, these receptors are directly related to the single most preventable cause of premature morbidity and mortality. In this chapter, we review some of the fundamental aspects of these receptors, with emphasis on the differences in pharmacology among the receptor subtypes and their unusual regulation by exposure to nicotine.
Norepinephrine/Epinephrine
Authors: Kozisek Megan E. , Bylund David B. 
Published: March 2007

AbstractNorepinephrine and epinephrine are catecholamine messengers that play important roles in the regulation of diverse physiological systems by acting through adrenergic receptors. The study of these biogenic amines has played an important historical role in the development of contemporary neuropharmacology. The study of the synthesis and metabolism of these compounds has provided important drug targets as has the study of the norepinephrine transporter. Adrenergic receptors are divided into three major types: α1, α2and β. Each of these major types has three or more subtypes. Many important therapeutic drugs act on this array of nine or more receptors. Genetic variations in all of the enzymes, transporters and receptors involved with norepinephrine and epinephrine are receiving intense study at the present time.
Neurobiology and Treatment of Depression
Authors: Neumeister Alexander , Charney Dennis S. , Sanacora Gerard , Krystal John H. 
Published: March 2007

AbstractDepression is increasingly understood as a disorder involving imbalances in brain neurobiologiocal systems and neuroanatomical disruptions, in the context of both, genetic and environmental factors. To understand the etiology of depression, it is important to characterize the interaction between brain neurobiological systems and their genetic regulation, and how this interaction affects behavior and neural circuits that are believed to be involved in the pathogenesis. This approach helps to identify novel targets for treatment which is on ongoing effort aiming to improve available treatments for depressed patients. This chapter reviews current concepts about the neurobiology of depression and provides state‐of‐the‐art information about potential novel treatment approaches which are currently developed.
Pharmacotherapy of Anxiety
Authors: Nash Jon R. , Nutt David J. 
Published: March 2007

AbstractThe diagnosis and management of anxiety disorders have evolved greatly during the past 50 years. For the clinician, a careful assessment of the patient is critical in formulating an appropriate treatment plan. Once a diagnosis has been made, a range of psychological and medical treatments are available. The authors suggest a structured classification of anxiety disorders according to their symptoms, and of drug therapies according to their mechanism of action. The evidence for effectiveness of medications in each of the major anxiety disorders is reviewed and a series of treatment algorithms are proposed. Likely future developments are considered.
MDMA and Other “Club Drugs”
Authors: Isabel Colado M. , O'Shea Esther , Richard Green A. 
Published: March 2007

AbstractThe use of the club drugs 3, 4‐methylenedioxymethamphetamine (MDMA, “ecstasy”), gamma‐hydroxybutyrate (GHB), flunitrazepam (Rohypnol), ketamine and LSD is a popular practice among young people especially during all‐night dance parties or “raves“ due to their ability to enhance social experiences and/or alter perception. These substances belong to different classes of drugs: MDMA is an amphetamine derived psychomotor stimulant, Rohypnol is a benzodiazepine, GHB and ketamine are anesthetic drugs while LSD is a hallucinogenic agent and therefore the immediate consequences of their abuse and intoxication can be very different. The long‐term consequences of the abuse of the different club drugs are of great concern. Animal studies indicate that MDMA causes long‐term 5‐HT damage and neuroimaging studies suggest this may also occur in humans. The development of addiction following the use of club drugs is also of concern since several of these drugs have been shown covers the most important aspects of the pharmacology of MDMA and the other club drugs and highlights some of the most important consequences of their abuse.
Advent of a New Generation of Antimigraine Medications
Authors: Recober Ana , Russo Andrew F. 
Published: March 2007

AbstractThis chapter will address recent developments in the treatment of migraine. The recent promising clinical trials using a new antimigraine medication, BIBN4096BS, heralds the advent of a new generation of therapeutics. BIBN4096BS targets the receptor for the neuropeptide calcitonin gene–related peptide (CGRP), which appears to play a causal role in migraine pain. We will discuss the rationale and therapeutic implications of modulating CGRP, including its potential for acting at multiple sites in the trigeminovasculature. We will then discuss the currently used acute and preventative pharmacological treatments. Of particular interest is the increasing evidence that antiepileptic drugs may be an effective prophylactic treatment for migraine. Future strategies to selectively downregulate CGRP synthesis and the potential use of migraine drugs for other forms of trigeminal‐mediated pain, such as temporomandibular disorder and trigeminal neuralgia, will be explored.
Epilepsy: Mechanisms of Drug Action and Clinical Treatment
Authors: Theodore William H. , Rogawski Michael A. 
Published: March 2007

AbstractSeizures can be caused by a wide range of brain disorders. Patients with two unprovoked seizures are considered to have epilepsy, and should receive antiepileptic drug treatment. The choice of drugs depends in part on diagnosis of the specific seizure syndrome, based on clinical, electroencephalographic, and neuroimaging data. Mechanisms of drugs action include modulation of voltage‐dependent neuronal ion channels, enhancement of GABA‐mediated inhibition, Inhibition of ionotropic glutamate receptor‐ mediated synaptic excitation, and modulation of glutamate release. Specific AED pharmacokinetics, particularly drug interactions, and toxicity, should be considered carefully in planning drug treatment. For patients with persistent seizures on optimal drug therapy, other options include diet, surgery, and brain stimulation.
Myelin Lipids and Proteins: Structure, Function, and Roles in Neurological Disorders
Authors: Quarles Richard H. 
Published: March 2007

AbstractThe objective of this chapter is to provide an overview of the lipids and proteins in myelin, which will serve as a foundation for other chapters in this section that cover neuroimmunogical aspects of disorders affecting myelin. The structure and functions of lipids and proteins of myelin are summarized. Other proteins localized in associated glial membranes, which have important roles in the formation and maintenance of myelinated axons, are also described. Finally, the roles of lipids and proteins as target antigens in the immunological aspects of demyelinating diseases are discussed.
Verbal overshadowing effect: how temporal perspective may exacerbate or alleviate the processing shift
Authors: Hunt Catherine , Carroll Marie 
Published: March 2007

AbstractGenerating a detailed, memory‐based description of a non‐verbal perceptual stimulus can impair later recognition of that stimulus—an effect termed verbal overshadowing (VO). After viewing a face for 10 seconds, half the participants wrote a description of it; the others completed an unrelated task. Participants then either imagined their proximal or distant future, or completed an unrelated task. Following a recognition test for the face previously presented, all the 75 participants attempted to solve three insight problems. A robust VO effect was observed for participants who imagined their proximal future; that is, providing a description of the face impaired their later recognition of that face. In contrast, those who imagined their distal future showed no such impairment. Furthermore, distal imagining participants solved more insight problems compared to proximal, and control condition participants. The results of this study provide support for a processing shift interpretation of VO. Copyright © 2007 John Wiley & Sons, Ltd.