bluuebunny/crossref_metadata_2025_split huggingface dataset:
Academician Yuri Fedorovich Isakov (1923–2016) (on the 100th anniversary of his birth)
Authors: Kurygin Al. A. , Semenov V. V. , Dovganyuk V. S. 
Published: April 2024

Outstanding pediatric surgeon, scientist, teacher and health care organizer, founder of a large school of pediatric surgeons, Honored Scientist of the RSFSR (1973), academician of the USSR Academy of Medical Sciences (1975) and the Russian Academy of Sciences (2013), vice-president of the Russian Academy of Medical Sciences (1989–2001), laureate of two State USSR Prizes (1979, 1985) and the State Prize of the Russian Federation (1999), Chief Pediatric Surgeon of the USSR Ministry of Health (1966–1981) and the Russian Ministry of Health (1992–2005), Deputy Minister of Health of the USSR (1981–1987), Professor Yuri Fedorovich Isakov was born on June28, 1923 in Kovrov, Vladimir region. In 1966, he was elected head of the department of surgical diseases of childhood at the 2nd Moscow Medical Institute named after N. I. Pirogov and led it for 40 years. The surgical and scientific activities of Yuri Fedorovich were distinguished by a very wide range of areas. On the problems of thoracic surgery, extensive experience has been accumulated in the treatment of children with diseases and malformations of the neck, chest, lungs, mediastinum, and esophagus. Many diverse research works have been carried out on topical issues of abdominal surgery. Yu. F. Isakov made a very large contribution to the development of endovideosurgery in children. The clinic became one of the first in the country to create a specialized endovideosurgical service. Under the leadership of Yuri Fedorovich and with his direct participation, pediatric nephrurology and vascular surgery quickly developed, scientific research was conducted on topical issues of combined trauma of the musculoskeletal system, an anesthesiology, resuscitation and intensive care service was organized in the clinic, fundamental research was carried out on the problem of pain management in children surgery. Yu. F. Isakov was the author and co-author of more than 500 scientific works, including 23 monographs and manuals, 7 textbooks and teaching aids. At the department headed by Yuri Fedorovich, 390 dissertations were defended, including 67 doctoral dissertations. Academician Yuri Fedorovich Isakov died on August 4, 2016 and was buried at the Troekurovskoye cemetery in Moscow.
Local negative pressure technique in abdominal surgery: advantages, disadvantages, controversial issues
Authors: Sazonov A. A. , Romashchenko P. N. , Makarov I. A. , Aliev R. K. , Maistrenko N. A. 
Published: April 2024

A literature review of studies on the use of local negative pressure technique (vacuum therapy) in abdominal surgery is presented. The article highlights modern approaches to its use in emergency pathology of the abdominal cavity and retroperitoneal space. The mechanisms of action, advantages and disadvantages of the local negative pressure technique, as well as the main morphofunctional aspects of its application are discussed in detail. Data from recent clinical studies and meta-analyses are summarized, and the effectiveness of using vacuum-assisted laparostomy within the framework of the «damage control» concept in multi-stage surgical treatment of injuries and urgent abdominal diseases accompanied by abdominal sepsis is demonstrated. The use of local negative pressure techniques can reduce postoperative mortality, as well as shorten the length of hospital treatment of patients. However, despite the obvious positive effect on the course of the wound process, vacuum therapy carries the risk of developing serious complications, the most dangerous of which are bleeding and perforation of hollow organs. In addition, it requires very expensive equipment and consumables, as well as training of medical personnel. Thus, the use of vacuum therapy requires a sound approach and a clear understanding of the technical features of its implementation. However, the indications for the use of local negative pressure in abdominal surgery have not yet been clarified, which undoubtedly hinders the wider introduction of this promising technique into clinical practice.
A Review on Deep Learning For Electroencephalogram Signal Classification
Authors: Kamil Gatfan Sarah 
Published: April 2024

Recently, the research on Electroencephalogram (EEG) signals have been obtained more focus at the same time the EEG signal is regarded as the basis for the prediction of diagnosis disease and the brain behavior. EEG is as significant tool for many conditions that can be recorded the brain human waves which accommodate the brain activity. In the recent decades, EEG data has been extensively applied in the approaches of data analysis such as time series analysis. With the considerable achievement of deep learning (DL) implement on the time series data, multiple studies have been began applying deep learning algorithms on the processing of EEG signal. Several deep learning techniques that assistant in the detection various psycho-neuro disorders, have been proposed in order to automate EEG detection and classification with great development in multiple applications of EEG signals. Also, different machine learning (ML) algorithms have been presented in such research for brain signals identification and classification in the era of Artificial intelligence (AI). In an attempt to summarize the EEG signal processing techniques, we have performed a literature review around deep learning algorithms for decoding the human’s brain activity as well as diagnosis disease and clarified particulars about several deep learning algorithms. We also conducted some of ML papers about EEG signals classification. Based on the achievement results of the research mentioned in this article appears an advanced scientific development in terms of deep learning.
Pengaruh Aset Pajak Tangguhan Dan Ukuran Perusahaan Terhadap Manajemen Laba Dengan Arus Kas Operasi Sebagai Variabel Pemoderasi
Authors: Rahayu Noviandhika Delphia , Nadi Luh 
Published: April 2024

Penelitian ini bertujuan untuk memberikan bukti empiris pengaruh aset pajak tangguhan dan ukuran perusahaan terhadap manajemen laba dengan arus kas operasional sebagai variabel moderasi. Penelitian ini menggunakan pendekatan kuantitatif dengan menggunakan data sekunder. Metode analisis yang digunakan dalam penelitian ini adalah analisis regresi data panel menggunakan Eviews. Sampel penelitian ini adalah perusahaan Industri yang terdaftar di Bursa Efek Indonesia (BEI) dari tahun 2017 – 2022 dengan metode purposive sampling dengan total 54 data observasi yang diolah dalam penelitian ini. Hasil penelitian menunjukkan bahwa manajemen laba dapat dipengaruhi secara simultan oleh aset pajak tangguhan dan ukuran perusahaan. Aset pajak tangguhan juga berpengaruh secara parsial terhadap manajemen laba, sementara ukuran perusahaan tidak berpengaruh. Arus kas operasi memberikan bukti dapat memoderasi pengaruh ukuran perusahaan terhadap manajemen laba, tetapi arus kas operasi tidak dapat memoderasi pengaruh aset pajak tangguhan terhadap manajemen laba.
Pedro Vicente Maldonado. Investigador y Geógrafo
Authors: Muñoz Juan Carlos 
Published: April 2024

Maldonado fue considerado unos de los científicos más importantes del siglo XVIII, fue un astrónomo, físico, matemático, geógrafo, topógrafo naturalista y político [1]. Formó parte de la delegación de investigadores que se dirigía a estudiar la ruta hacia el río Amazonas. Descubrió el árbol del caucho y los usos que los nativos le daban. Fue el creador de la ruta Quito -Esmeraldas. En 1736 llega al Ecuador la Misión Geodésica Francesa, para establecer los 00´00´´00´´ de la latitud de la tierra, donde se declara científicamente a Quito como “la mitad del mundo” [2].
En 1744 viajó por varios países europeos como: España, Francia e Inglaterra, donde compartió sus trabajos investigativos, causando gran impresión entre sus colegas científicos de la época [3]. Se considera como su obra más representativa respecto a las posesiones ultramarinas de los europeos a “Mapa del reino de Quito”.
The effect of 1-deoxynojirimycin isolated from logging residue of Bagassa guianensis on an in vitro cancer model
Authors: Fonseca Susanne Suely Santos da , Rodrigues Thaíssa Vitória Portal , Pinheiro Wandson Braamcamp de Souza , Teixeira Eliel Barbosa , dos Santos Kyouk Isabel Portilho , da Silva Marcelli Geisse de Oliveira Prata , de Sousa Amanda Marques , do Vale Débora Monteiro Carneiro , Pinho Jaqueline Diniz , Araújo Taíssa Maíra Thomaz , Khayat André Salim , Pereira Antonio 
Published: April 2024

Introduction:Bagassa guianensis Aubl, a tree widely distributed in Brazil, significantly contributes to the furniture industry. Notably, it harbors the bioactive compound 1-deoxynojirimycin (1-DNJ), which is retrievable from timber residues and retains activity even days after wood extraction. This makes Bagassa guianensis a promising biological resource for anticancer therapy and pharmacology studies. This study delves into the in vitro antineoplastic actions of 1-DNJ, focusing on adenocarcinoma gastric cell lines (ACP02) and glioblastoma (A172).Methods: The effect of 1-DNJ on cell viability was evaluated after 72 hours of treatment in the ACP02 and A172 cell lines. We also assessed the effect of 1-DNJ on the pattern of cell migration, cell death, changes in the cell cycle by flow cytometry, the production of reactive oxygen, and its antioxidant capacity in the scavenging of free radicals.Results: Assessing cell viability after 72 h (about 3 days) of treatment reveals a remarkable reduction, particularly in glioblastoma cells (A172), exhibiting a lower IC50 compared to ACP02 and MRC5 (fibroblast derived from normal lung tissue) cell lines. This decreased viability correlates with reduced reactive oxygen species (ROS) production in both cell lines after the treatment with 1-DNJ. Furthermore, 1-DNJ induces cell cycle arrest, impedes cell migration, and prompts cell death in ACP02 and A172.Discussion: These findings support 1-DNJ as a potent antineoplastic agent, particularly efficacious against glioblastoma and gastric adenocarcinoma. Thus, unveiling the therapeutic potential of Bagassa guianensis Aubl for cancer treatment and expanding the horizons of bioeconomy applications.
Recent food alerts and analytical advances related to the contamination of tropane and pyrrolizidine alkaloids in food
Authors: Casado Natalia , Gañán Judith , Morante-Zarcero Sonia , Sierra Isabel 
Published: April 2024

The food control of tropane and pyrrolizidine alkaloids has become in recent years in Europe one of the main priorities within the food safety field due to the exponential increase in food alerts related to the concerning levels of these natural toxins in foods. This awareness has led to increasing progress in the research and determination of these compounds. Hence, this mini-review provides a brief and comprehensive overview of the evolution of these food alerts, highlighting the main food products frequently contaminated with these alkaloids and reviewing the analytical advances in their determination within the las 3 years (from 2020 to 2023).
Association of the systemic immuno-inflammation index, neutrophil-to-lymphocyte ratio, and platelet-to-lymphocyte ratio with diabetic microvascular complications
Authors: Li Jiahang , Wang Xueying , Jia Wenjing , Wang Kai , Wang Wenju , Diao Weibo , Ou Feiya , Ma Jing , Yang Yan 
Published: April 2024

BackgroundThe systemic immuno-inflammation index (SII), neutrophil-to-lymphocyte ratio (NLR), and platelet-to-lymphocyte ratio (PLR) are widely used and have been shown to be predictive indicators of various diseases. Diabetic nephropathy (DN), retinopathy (DR), and peripheral neuropathy (DPN) are the most prominent and common microvascular complications, which have seriously negative impacts on patients, families, and society. Exploring the associations with these three indicators and diabetic microvascular complications are the main purpose.MethodsThere were 1058 individuals with type 2 diabetes mellitus (T2DM) in this retrospective cross-sectional study. SII, NLR, and PLR were calculated. The diseases were diagnosed by endocrinologists. Logistic regression and subgroup analysis were applied to evaluate the association between SII, NLP, and PLR and diabetic microvascular complications.ResultsSII, NLR, and PLR were significantly associated with the risk of DN [odds ratios (ORs): 1.52, 1.71, and 1.60, respectively] and DR [ORs: 1.57, 1.79, and 1.55, respectively] by multivariate logistic regression. When NLR ≥2.66, the OR was significantly higher for the risk of DPN (OR: 1.985, 95% confidence interval: 1.29–3.05). Subgroup analysis showed no significant positive associations across different demographics and comorbidities, including sex, age, hypertension, HbA1c (glycated hemoglobin), and dyslipidemia.ConclusionThis study found a positive relationship between NLR and DN, DR, and DPN. In contrast, SII and PLR were found to be only associated with DN and DR. Therefore, for the diagnosis of diabetic microvascular complications, SII, NLR and PLR are highly valuable.
A comparative study on the combination of life cycle assessment and ecological footprints: solar photovoltaic power generation vs. coal power generation in Ningxia
Authors: Luo Jinni , Yang Hexu , Zhang Liangxia , Liu He , Wang Yidan , Hao Chen 
Published: April 2024

In China, where energy activities, predominantly driven by fossil fuel combustion, account for nearly 90% of the country’s greenhouse gas (GHG) emissions and coal power alone contributes over 40%, the shift towards carbon neutrality is a critical national ambition. This study conducts a comprehensive comparison of the environmental impacts of solar photovoltaic power generation (SPPG) and coal power, employing both life cycle assessment and ecological footprint analysis. We meticulously analyze the complete lifecycle of SPPG, pinpointing key stages of GHG emissions, and offer nuanced, localized policy recommendations. Our findings indicate that a 1 kWp SPPG module emits 1,601.18 kg of GHGs over its lifespan, equating to 1.35 kg/kW·h per unit of electricity produced—substantially lower than the 4.81 kg/kW·h emitted by coal power, thus highlighting the latter’s heightened environmental detriment. Additionally, this study assesses the ecological footprint of both energy sources in Ningxia. SPPG emerges with an ecological surplus, showcasing a per capita footprint of 0.0342 hm2, compatible with Ningxia’s ecological capacity. In stark contrast, coal power exhibits a sustained ecological deficit over the past 5 years, with a growing per capita footprint of 0.6529 hm2, underscoring its unsustainability. This research provides a detailed comparative analysis of the environmental impacts of SPPG and coal power in Ningxia, offering valuable insights for energy policymakers and industry stakeholders. It underscores the urgent need for industrial restructuring towards more sustainable and renewable energy sources, aligning with China’s broader objectives of environmental preservation and achieving carbon neutrality.
Optimization and classification control of permanent basic farmland based on quality classification
Authors: Wang Wei , Chen Yiling , Liu Kun , Dang Yingchun , Li Guilong , Wen Liangyou , Cao Yun 
Published: April 2024

Permanent basic farmland plays an important role in stabilizing agricultural production and ensuring national food security. Therefore, it is necessary to reasonably delineate and control permanent basic farmland. This article is based on the idea of classifying the quality of cultivated land resources, combined with the rules for the delineation of permanent basic farmland, and from the perspective of the synergy of “suitability-connectivity-stability” of cultivated land, a indicator system is constructed. Application of suitability, connectivity, and stability evaluation methods. Taking Zhangshu City, Jiangxi Province as an example, the status of cultivated land resources is comprehensively evaluated, and permanent basic farmland is optimized and graded for protection. The results show that: (1) the arable land in Zhangshu City is mainly of medium suitability, medium continuity and high stability. (2) Zhangshu City is divided into 43218.80 hm2 of permanent basic farmland, accounting for 79.35% of the total area of cultivated land. (3) Control and partition permanent basic farmland into three categories: core protected areas for permanent basic farmland, quality improvement areas, and key transformation areas. The above results indicate that this evaluation has a supportive role in supporting the spatial optimization and hierarchical management of permanent basic farmland, and is of great significance for the unified management of natural resources.
The application of virtual synchronous generator technology in inertial control of new energy vehicle power generation
Authors: Du Meng , Mei Hailong 
Published: April 2024

Introduction: With the rapid development of human society and economy, the power generation technology of various new energy vehicles has begun to receive widespread attention.Methods: Due to the lack of inertia and frequency stability in the new energy vehicle power generation system, this paper proposes a power generation control method that combines linear active disturbance rejection control technology and virtual synchronous generator technology. This method first introduces the control strategy and inertial response of the virtual synchronous generator. Then, it uses linear active disturbance rejection control technology to improve the virtual synchronous generator technology to deal with the uncertainty and external interference in the system.Results: The results showed that when the virtual inertia coefficient was 0, and the new energy vehicles would hardly intervene in the regulation of the grid voltage. When the virtual inertia coefficient was 5, the decline rate of the DC bus voltage of new energy vehicles had slowed down. When the virtual inertia coefficient increased, the power output of new energy vehicles can be increased to the grid. When the load suddenly increased, and the corresponding DC bus voltage decreased more slowly. In the VSG output power comparison, under the research method, the frequency fluctuation only increased by 0.09 Hz and returned to the rated frequency of 50 Hz. Additionally, the dynamic process of the system output power was the shortest, lasting only 0.05 s.Discussion: The above results show that the research method has significant superiority and effectiveness in improving the inertial response and overall stability of the new energy vehicle power system.
Causal association between gut microbiomes and different types of aneurysms: a Mendelian randomization study
Authors: Qiu Youjia , Hou Yucheng , Wei Xingzhou , Wang Menghan , Yin Ziqian , Xie Minjia , Duan Aojie , Ma Chao , Si Ke , Wang Zhong 
Published: April 2024

BackgroundPrevious studies suggests that gut microbiomes are associated with the formation and progression of aneurysms. However, the causal association between them remains unclear.MethodsA two-sample Mendelian randomization was conducted to investigate whether gut microbiomes have a causal effect on the risk of intracerebral aneurysm (IA), thoracic aortic aneurysm (TAA) and abdominal aortic aneurysm (AAA), and aortic aneurysm (AA). Single nucleotide polymorphisms (SNPs) smaller than the locus-wide significance level (1 × 10−5) were selected as instrumental variables. We used inverse-variance weighted (IVW) test as the primary method for the evaluation of causal association. MR-Egger, weighted median, weighted mode, and MR Pleiotropy Residual Sum and Outlier (MR-PRESSO) methods were conducted for sensitive analysis. The p-value was adjusted by the false discovery rate (FDR) which adjust the results of multiple comparisons, a p &lt; 0.05 and q &lt; 0.1 was considered a significant causal association. Additionally, a p &lt; 0.05 and q &gt; 0.1 was considered a suggestive causal effect. Additionally, reverse MR was also performed to exclude the possibility of reverse causality.ResultsThe phylum Firmicutes (OR = 0.62; 95% CI, 0.48–0.81), class Lentisphaeria (OR = 0.75; 95% CI, 0.62–0.89), and order Victivallales (OR = 0.75; 95% CI, 0.62–0.89) have a causal protective effect on the risk of AAA. Additionally, class Verrucomicrobia, class Deltaproteobacteria, order Verrucomicrobiale, family Verrucomicrobiacea, genus Eubacterium rectale group, genus Akkermansia, and genus Clostridium innocuum group were negatively associated with the risk of different types of aneurysms, whereas class Negativicutes, order Selenomonadales, and genus Roseburia had positive causal association with different types of aneurysms (p &lt; 0.05; q &gt; 0.1). Further sensitivity analysis validated the robustness of our MR results, and no reverse causality was found with these gut microbiomes (p &gt; 0.05).ConclusionOur MR analysis confirmed the causal association of specific gut microbiomes with AAA, and these microbiomes were considered as protective factors. Our result may provide novel insights and theoretical basis for the prevention of aneurysms through regulation of gut microbiomes.
Development and feasibility of a mindfulness-based dance/movement therapy intervention for chronic low back pain
Authors: Shim Minjung , Gaydos Monica , Goldstein-Levitas Natasha , Musalo Nicole , Prakash Nalini , Bradt Joke , Zhang Fengqing , Wenger Sarah , Gonzalez Adam 
Published: April 2024

IntroductionResponding to the need for innovative, multi-modal, non-pharmacological strategies in chronic low back pain (cLBP) care, this article presents the development and a mixed methods feasibility trial of a manualized Mindfulness-based Dance/Movement Therapy (M-DMT) program for cLBP. The 12-week program is designed as a group therapy, integrating mindfulness principles, creative/expressive dance and movement, and psychoeducational content focused on cLBP management. This holistic program seeks to cultivate nonjudgmental awareness of pain experiences, challenge maladaptive pain-related beliefs, enhance emotional well-being, foster social support, and promote effective coping strategies for the daily challenges associated with cLBP.MethodsThe 12-week M-DMT intervention was administered to individuals with non-specific cLBP (N = 18, aged 51.7 ± 13.9 years, 72% female, 55% Black and 39% White). We assessed feasibility and acceptability through monitoring enrollment and retention rates, attendance, and adverse events. Moreover, we measured the intervention's credibility/expectancy, participants' perception of changes, and overall satisfaction. Additionally, we collected qualitative data, capturing participants' perspectives on the intervention's usefulness and perceived benefits. Specific benchmarks were established to gauge the successful feasibility and acceptability of the program.ResultsThe adherence rate stood at 80%, with a perfect retention rate of 100%. The study successfully met the benchmarks for treatment acceptability and satisfaction criteria, with 61% of participants reporting “feeling better” or a “great deal better” after the intervention. No adverse events were observed. Participants found the intervention enjoyable and reported that it provided effective tools for cLBP and related symptoms. Notably, participants reported a decrease in fear-avoidance behaviors, increased motivation for physical activity, and a boost in self-efficacy for pain management.DiscussionThese encouraging findings establish a strong basis for considering the M-DMT intervention as a promising approach for cLBP management, warranting further investigation in larger-scale studies.