bluuebunny/crossref_metadata_2025_split huggingface dataset:
MATCHING RESULTS OF TWO INDEPENDENT HIGHLY TRAINED SENSORY PANELS USING DIFFERENT DESCRIPTIVE ANALYSIS METHODS1
Authors: LOTONG VARAPHA , CHAMBERS DELORES H. , DUS CLARE , IV EDGAR CHAMBERS , CIVILLE GAIL V. 
Published: May 2007

ABSTRACTTwo independent, highly trained panels separately conducted descriptive analysis of orange juices using different descriptive analysis methods and sets of samples. Lexicons were developed independently. One panel evaluated 23 orange juice products and identified and referenced 24 attributes. The other panel evaluated 17 products and identified 17 attributes for testing. Though not identical, the lexicons developed by both panels were similar overall. To compare the sensory space of the product category, Principal Component Analysis (PCA) and sensory maps were developed separately for each panel. The comparison showed that the underlying sample spaces obtained from both panels were comparable in many ways. Key flavor characteristics for the same types of orange juice products were described similarly by both panels. These data indicate that the process of using highly trained panels that define attributes and use reference standards for descriptive sensory analysis can give objective and comparable information for a product category across different panels.
DETERMINATION OF THE SENSORY ATTRIBUTES OF DRIED MILK POWDERS AND DAIRY INGREDIENTS
Authors: DRAKE M.A. , KARAGUL‐YUCEER Y. , CADWALLADER K.R. , CIVILLE G.V. , TONG P.S. 
Published: May 2007

ABSTRACTA standardized descriptive language for skim milk powder and dried dairy ingredients was developed. The lexicon was initially identified from a large sample set of dried dairy ingredients (138). A highly trained descriptive panel (n = 14) refined terms and identified references. Dried dairy ingredients (36) were then evaluated using the developed language. Twenty‐one descriptors were identified for dried dairy ingredients. Seventeen flavors and tastes were identified in skim milk powders (27) with nine flavors/tastes observed in all skim milk powders. Dried dairy ingredients were differentiated using the language (P<0.05). There were flavors common to all dried dairy ingredients while other flavors were specific to particular products.
PERCEIVED EATING DIFFICULTIES AND PREFERENCES FOR VARIOUS TEXTURES OF RAW AND COOKED CARROTS IN YOUNG AND ELDERLY SUBJECTS
Authors: ROININEN KATARIINA , FILLION LAURENCE , KILCAST DAVID , LÄHTEENMÄKI LIISA 
Published: May 2007

ABSTRACTThe aim of the study was to determine how those texture attributes that elderly people find difficult to eat are related to their preferences for different modifications of carrot textures. This study was conducted with same methods in Finland and in the United Kingdom (UK). Trained sensory panels in both countries described sensory profiles of a range of carrot samples with same glossary of texture terms. The texture of carrot samples was manipulated using different preparation and cooking methods. Based on the Principal Component Analysis (PCA), boiled and puréed samples were perceived as soft, wet, pulpy and smooth, whereas raw samples were dry, brittle, rough, crispy and crunchy. Two age groups were used for the consumer tests: a young adult group aged 23 to 40 years, mean 32 (Finland) and 33 (UK) and an elderly group aged over 60 years, mean 75 (Finland) and 76 (UK). Both the elderly and young adult respondents considered samples as difficult to eat if they needed a long chewing time, were crunchy, hard, brittle, dry, rough or sharp, such as raw slices and coarsely grated samples. On the other hand, slimy, wet, smooth, soft and pulpy samples, such as boiled carrots and purée, were considered as easy‐to‐eat. The young adults liked more difficult textures such as rough, crispy, crunchy and hard than did the elderly respondents, but the easiest textures were not liked by either age group. Subjects with dental deficiencies liked easier textures more than those fully dentate.
COMPARISON OF SENSORY PROFILES DONE BY TRAINED AND UNTRAINED JURIES: METHODOLOGY AND RESULTS
Authors: HUSSON F. , PAGÈS J. 
Published: May 2007

ABSTRACTWe compare the sensory profiles of six dark chocolates done by two types of juries: some trained juries and an untrained jury. Six laboratories, each one made up of 10 to 15 judges, are regarded as trained juries since the assessors were well trained before the evaluation of the products. The second type of jury is composed of only one panel of 29 untrained assessors and this jury is named the untrained jury. Fourteen attributes were evaluated and analyses of variance have been carried out by attribute to compare the sensory profiles of the six chocolates done by the trained juries and by the untrained jury. These analyses of variance show that the two types of juries give similar sensory profiles and that the few differences are mainly due to different ways of using the scale.
Studies on uroporphyrinogen decarboxylase fromChlorella kessleri(Trebouxiophyceae, Chlorophyta)
Authors: Juárez Angela B. , Aldonatti Carmen , Vigna María S. , Ríos de Molina María del C. 
Published: May 2007

Uroporphyrinogen decarboxylase (UroD) (EC 4.1.1.37) is an enzyme from the tetrapyrrole biosynthetic pathway, in which chlorophyll is the main final product in algae. This is the first time that a study on UroD activity has been performed in a green alga ( Chlorella ). We isolated and partially purified the enzyme from a Chlorella kessleri (Trebouxiophyceae, Chlorophyta) strain (Copahue, Neuquén, Argentina), and describe for the first time some of its properties. In C. kessleri, the decarboxylation of uroporphyrinogen III occurs in two stages, via 7 COOH and then 6 and 5 COOH intermediates, with the decarboxylation of the 7 COOH compound being the rate-limiting step for the reaction. Cultures in the exponential growth phase showed the highest specific activity values. The most suitable conditions to measure UroD activity in C. kessleri were as follows: 0.23–0.3 mg protein/mL, ?6–8 μmol/L uroporphyrinogen III, and 20 min incubation time. Gel filtration chromatography and Western blot assays indicated that UroD from C. kessleri is a dimer of approximately 90 kDa formed by species of lower molecular mass, which conserves enzymatic activity.
Role of chitinase and β-1,3-glucanase activities produced by a fluorescent pseudomonad and in vitro inhibition ofPhytophthora capsiciandRhizoctonia solani
Authors: Arora Naveen Kumar , Kim Min Jeong , Kang Sun Chul , Maheshwari Dinesh Kumar 
Published: May 2007

A study was conducted to investigate the possibility of involvement of chitinase and β-1,3-glucanase of an antagonistic fluorescent Pseudomonas in growth suppression of phytopathogenic fungi, Phytophthora capsici and Rhizoctonia solani . Fluorescent Pseudomonas isolates GRC3and GRC4were screened for their antifungal potential against phytopathogenic fungi by using dual culture technique both on solid and liquid media. The percent inhibition was calculated. Various parameters were monitored for optimization of enzyme activities by fluorescent Pseudomonas GRC3. The involvement of chitinases, β-1,3-glucanases, and antifungal metabolites of nonenzymatic nature was correlated with the inhibition of P. capsici and R. solani. The results provide evidence for antibiosis as a mechanism for antagonism. The study also confirms that multiple mechanisms are involved in suppressing phytopathogens as evidenced by the involvement of chitinase and β-1,3-glucanase in inhibition of R. solani but not P. capsici by isolate GRC3.
Decoloration of Amaranth by the white-rot fungusTrametes versicolor. Part I. Statistical analysis
Authors: Gavril Mihaela , Hodson Peter V. , McLellan Jim 
Published: May 2007

The white-rot fungus Trametes versicolor decolorized the mono-azo-substituted naphthalenic dye Amaranth. The relationship between the amount of enzymes present in the system and the efficiency of the decoloration process was investigated. The two responses used to quantify the process of decoloration (i.e., initial decoloration rate, v0, and the percent concentration of dye decolorized in 1 h, %c) were correlated with the amount of three enzymes considered for the study (lignin peroxidase, manganese peroxidase, and laccase) and analyzed through stepwise regression analysis (forward, backward, and mixed). The results of the correlation analysis and those of the regression analysis indicated that lignin peroxidase is the enzyme having the greatest influence on the two responses.
Comparison of rhizobia that nodulate Medicago laciniata and Medicago truncatula present in a single Tunisian arid soil
Authors: Badri Y. , Zribi K. , Badri M. , Huguet T. , van Berkum P. , Aouani M.E. 
Published: May 2007

The rhizobia present in a single arid region Tunisian soil that nodulate Medicago laciniata and Medicago truncatula were compared. All isolates, 40 from each host, were Sinorhizobium meliloti based on 16S rRNA polymerase chain reaction restriction fragment length polymorphism (PCR–RFLP) patterns and subsequent confirmation by sequence analysis of the 16S rRNA genes in four representatives from each host species. There was no apparent relationship between Medicago host species of isolation and the nodulating rhizobial genome as determined by repetitive extragenic palandromic PCR. The isolates of M. laciniata were distinguished from those of M. truncatula present in the same soil by variation in PCR–RFLP of nifDK, indicating that this dissimilarity is originally genetic and not geographic. While forming effective symbioses with their own respective isolates, both M. laciniata and M. truncatula formed ineffective true nodules, nodule-like structures, or no nodules at all in cross-inoculation tests, as confirmed by the histological observations.
Myeloid Cell Leukemia-1 Inversely Correlates with Glycogen Synthase Kinase-3β Activity and Associates with Poor Prognosis in Human Breast Cancer
Authors: Ding Qingqing , He Xianghuo , Xia Weiya , Hsu Jung-Mao , Chen Chun-Te , Li Long-Yuan , Lee Dung-Fang , Yang Jer-Yen , Xie Xiaoming , Liu Jaw-Ching , Hung Mien-Chie 
Published: May 2007

Abstract
Myeloid cell leukemia-1 (Mcl-1), an antiapoptotic Bcl-2 family member, is overexpressed in many types of human cancer and associates with cell immortalization, malignant transformation, and chemoresistance. Glycogen synthase kinase-3β (GSK-3β), a key component of the Wnt signaling pathway, is involved in multiple physiologic processes such as protein synthesis, tumorigenesis, and apoptosis. Here, we report that expression of Mcl-1 was correlated with phosphorylated GSK-3β (p-GSK-3β) at Ser9 (an inactivated form of GSK-3β) in multiple cancer cell lines and primary human cancer samples. In addition, Mcl-1 was strikingly linked with poor prognosis of human breast cancer, in which the high level of Mcl-1 was related to high tumor grade and poor survival of breast cancer patients. Furthermore, we found that activation of GSK-3β could down-regulate Mcl-1 and was required for proteasome-mediated Mcl-1 degradation. Under some physiologic conditions, such as UV irradiation, anticancer drug treatment, and inhibition of growth factor pathways, Mcl-1 was down-regulated through activation of GSK-3β. Our results indicate that Mcl-1 stabilization by GSK-3β inactivation could be involved in tumorigenesis and serve as a useful prognostic marker for human breast cancer. [Cancer Res 2007;67(10):4564–71]
Inhibition of p38α Mitogen-Activated Protein Kinase Prevents the Development of Osteolytic Bone Disease, Reduces Tumor Burden, and Increases Survival in Murine Models of Multiple Myeloma
Authors: Vanderkerken Karin , Medicherla Satya , Coulton Les , De Raeve Hendrik , Willems Angelo , Lawson Michelle , Van Camp Ben , Protter Andrew A. , Higgins Linda S. , Menu Eline , Croucher Peter I. 
Published: May 2007

AbstractThe bone microenvironment plays a critical role in supporting the growth and survival of multiple myeloma as well as in the development of osteolytic bone disease. Signaling through p38α mitogen-activated protein kinase (MAPK) mediates synthesis of multiple myeloma cell growth factors, and its inhibition reduces proliferation in vitro. However, it is unclear whether targeting p38α MAPK prevents multiple myeloma growth and the development of bone disease in vivo. In this study, we determined whether SCIO-469, a selective p38α MAPK inhibitor, inhibits multiple myeloma growth and prevents bone disease in the 5T2MM and 5T33MM models. SCIO-469 decreased constitutive p38α MAPK phosphorylation of both 5T2MM and 5T33MM cells in vitro. This was associated with decreased DNA synthesis and an induction of apoptosis when the cells were cultured with bone marrow stromal cells. Treatment of C57Bl/KaLwRij mice bearing 5T33MM cells with SCIO-469 inhibited p38α MAPK phosphorylation and was associated with a significant decrease in serum paraprotein, an almost complete reduction in tumor cells in the bone marrow, a decrease in angiogenesis, and a significant increase in disease-free survival. Injection of 5T2MM murine myeloma cells into C57Bl/KaLwRij mice resulted in myeloma bone disease characterized by increased osteoclast occupation of the bone surface, reduced cancellous bone, and the development of osteolytic bone lesions. Treatment of 5T2MM-injected mice with SCIO-469 reduced this development of bone disease. Together, these data show that targeting p38α MAPK with SCIO-469 decreases myeloma burden in vivo, in addition to preventing the development of myeloma bone disease. [Cancer Res 2007;67(10):4572–7]
The 2006 William Feinberg Lecture
Authors: Sacco Ralph L. 
Published: May 2007

By the year 2010, it is estimated that 18.1 million people worldwide will die annually because of cardiovascular diseases and stroke. “Global vascular risk” more broadly includes the multiple overlapping disease silos of stroke, myocardial infarction, peripheral arterial disease, and vascular death. Estimation of global vascular risk requires consideration of a variety of variables including demographics, environmental behaviors, and risk factors. Data from multiple studies suggest continuous linear relationships between the physiological vascular risk modulators of blood pressure, lipids, and blood glucose rather than treating these conditions as categorical risk factors. Constellations of risk factors may be more relevant than individual categorical components.
Exciting work with novel risk factors may also have predictive value in estimates of global vascular risk. Advances in imaging have led to the measurement of subclinical conditions such as carotid intima-media thickness and subclinical brain conditions such as white matter hyperintensities and silent infarcts. These subclinical measurements may be intermediate stages in the transition from asymptomatic to symptomatic vascular events, appear to be associated with the fundamental vascular risk factors, and represent opportunities to more precisely quantitate disease progression. The expansion of studies in molecular epidemiology and detection of genetic markers underlying vascular risks also promises to extend our precision of global vascular risk estimation.
Global vascular risk estimation will require quantitative methods that bundle these multi-dimensional data into more precise estimates of future risk. The power of genetic information coupled with data on demographics, risk-inducing behaviors, vascular risk modulators, biomarkers, and measures of subclinical conditions should provide the most realistic approximation of an individual’s future global vascular risk. The ultimate public health benefit, however, will depend on not only identification of global vascular risk but also the realization that we can modify this risk and prove the prediction models wrong.
Influence of the North American Monsoon Experiment (NAME) 2004 Enhanced Soundings on NCEP Operational Analyses
Authors: Mo Kingtse C. , Rogers Eric , Ebisuzaki Wesley , Higgins R. Wayne , Woollen J. , Carrera M. L. 
Published: May 2007

Abstract
During the 2004 North American Monsoon Experiment (NAME) field campaign, an extensive set of enhanced atmospheric soundings was gathered over the southwest United States and Mexico. Most of these soundings were assimilated into the NCEP operational global and regional data assimilation systems in real time. This presents a unique opportunity to carry out a series of data assimilation experiments to examine their influence on the NCEP analyses and short-range forecasts. To quantify these impacts, several data-withholding experiments were carried out using the global Climate Data Assimilation System (CDAS), the Regional Climate Data Assimilation System (RCDAS), and the three-dimensional variational data assimilation (3DVAR) Eta Model Data Assimilation System (EDAS) for the NAME 2004 enhanced observation period (EOP).
The impacts of soundings vary between the assimilation systems examined in this study. Overall, the influence of the enhanced soundings is concentrated over the core monsoon area. While differences at upper levels are small, the differences at lower levels are more substantial. The coarse-resolution CDAS does not properly resolve the Gulf of California (GoC), so the assimilation system is not able to exploit the additional soundings to improve characteristics of the Gulf of California low-level jet (GCLLJ) and the associated moisture transport in the GoC region. In contrast, the GCLLJ produced by RCDAS is conspicuously stronger than the observations, though the problem is somewhat alleviated with additional special NAME soundings. For EDAS, soundings improve the intensity and position of the Great Plains low-level jet (GPLLJ). The soundings in general improve the analyses over the areas where the assimilation system has the largest uncertainties and errors. However, the differences in regional analyses owing to the soundings are smaller than the differences between the two regional data assimilation systems.
Sensitivity to Horizontal Resolution in the AGCM Simulations of Warm Season Diurnal Cycle of Precipitation over the United States and Northern Mexico
Authors: Lee Myong-In , Schubert Siegfried D. , Suarez Max J. , Held Isaac M. , Kumar Arun , Bell Thomas L. , Schemm Jae-Kyung E. , Lau Ngar-Cheung , Ploshay Jeffrey J. , Kim Hyun-Kyung , Yoo Soo-Hyun 
Published: May 2007

Abstract
This study examines the sensitivity of the North American warm season diurnal cycle of precipitation to changes in horizontal resolution in three atmospheric general circulation models, with a primary focus on how the parameterized moist processes respond to improved resolution of topography and associated local/regional circulations on the diurnal time scale. It is found that increasing resolution (from approximately 2° to ½° in latitude–longitude) has a mixed impact on the simulated diurnal cycle of precipitation. Higher resolution generally improves the initiation and downslope propagation of moist convection over the Rockies and the adjacent Great Plains. The propagating signals, however, do not extend beyond the slope region, thereby likely contributing to a dry bias in the Great Plains. Similar improvements in the propagating signals are also found in the diurnal cycle over the North American monsoon region as the models begin to resolve the Gulf of California and the surrounding steep terrain. In general, the phase of the diurnal cycle of precipitation improves with increasing resolution, though not always monotonically. Nevertheless, large errors in both the phase and amplitude of the diurnal cycle in precipitation remain even at the highest resolution considered here. These errors tend to be associated with unrealistically strong coupling of the convection to the surface heating and suggest that improved simulations of the diurnal cycle of precipitation require further improvements in the parameterizations of moist convection processes.
Spatial and Temporal Patterns of Precipitation Intensity as Observed by the NAME Event Rain Gauge Network from 2002 to 2004
Authors: Gochis David J. , Watts Christopher J. , Garatuza-Payan Jaime , Cesar-Rodriguez Julio 
Published: May 2007

Abstract
Detailed information on the spatial and temporal characteristics of precipitation intensity from the mountainous region of northwest Mexico has, until recently, been lacking. As part of the 2004 North American Monsoon Experiment (NAME) enhanced observing period (EOP) surface rain gauge networks along with weather radar and orbiting satellites were employed to observe precipitation in a manner heretofore unprecedented for this semiarid region. The NAME Event Rain gauge Network (NERN), which has been in operation since 2002, contributed to this effort. Building on previous work, this paper presents analyses on the spatial and temporal characteristics of precipitation intensity as observed by NERN gauges. Analyses from the 2004 EOP are compared with the 2002–04 period and with long-term gauge observations. It was found that total precipitation from July to August of 2004 was similar in spatial extent and magnitude to the long-term average, though substantially wetter than 2003. Statistical analyses of precipitation intensity data from the NERN reveal that large precipitation events at hourly and daily time scales are restricted to coastal and low-elevation areas west of the Sierra Madre Occidental. At 10-min time scales, maximum intensity values equal to those at low elevations could be observed at higher elevations though they were comparatively infrequent. It is also shown that the inclusion of NERN observations in existing operational analyses helps to correct significant biases, which, on the seasonal time scale, are of similar magnitude as the interannual variability in precipitation in key headwater regions of northwest Mexico.
Modeling Intraseasonal Features of 2004 North American Monsoon Precipitation
Authors: Gao X. , Li J. , Sorooshian S. 
Published: May 2007

Abstract
This study examines the capabilities and limitations of the fifth-generation Pennsylvania State University–National Center for Atmospheric Research Mesoscale Model (MM5) in predicting the precipitation and circulation features that accompanied the 2004 North American monsoon (NAM). When the model is reinitialized every 5 days to restrain the growth of modeling errors, its results for precipitation checked at subseasonal time scales (not for individual rainfall events) become comparable with ground- and satellite-based observations as well as with the NAM’s diagnostic characteristics. The modeled monthly precipitation illustrates the evolution patterns of monsoon rainfall, although it underestimates the rainfall amount and coverage area in comparison with observations. The modeled daily precipitation shows the transition from dry to wet episodes on the monsoon onset day over the Arizona–New Mexico region, and the multiday heavy rainfall (&gt;1 mm day−1) and dry periods after the onset. All these modeling predictions agree with observed variations. The model also accurately simulated the onset and ending dates of four major moisture surges over the Gulf of California during the 2004 monsoon season. The model reproduced the strong diurnal variability of the NAM precipitation, but did not predict the observed diurnal feature of the precipitation peak’s shift from the mountains to the coast during local afternoon to late night. In general, the model is able to reproduce the major, critical patterns and dynamic variations of the NAM rainfall at intraseasonal time scales, but still includes errors in precipitation quantity, pattern, and timing. The numerical study suggests that these errors are due largely to deficiencies in the model’s cumulus convective parameterization scheme, which is responsible for the model’s precipitation generation.