bluuebunny/crossref_metadata_2025_split huggingface dataset:
Peningkatan Pengetahuan Masyarakat dalam Penggunaan Oralit dan Zink dalam Penanganan Diare
Authors: Fadhilah Nur Aina , Herlina Reza , Sandi Dita Ayulia Dwi , Rochani Hardina 
Published: March 2024

Diare merupakan suatu kondisi dimana terjadi buang air besar dalam bentuk cairan yang terjadi lebih dari 3 kali sehari. Diare biasanya disertai dengan nyeri di bagian bawah perut. Kondisi ini dapat terjadi karena mengkonsumsi makanan dan minuman yang tercemar virus, bakteri, atau parasit; malabsorpsi, alergi, keracunan, imunodefisiensi, keracunan, dan penyebab lainnya. Tujuan dari kegiatan promosi kesehatan ini adalah untuk memberikan pengetahuan dan informasi mengenai penggunaan oralit dan zink saat diare. Pelaksanaan promosi kesehatan ini dilakukan dengan memberikan pretest di awal kegiatan dilanjutkan dengan pemberian informasi dengan metode ceramah dan pembagian media berupa leaflet. Selanjutnya diadakan posttest di akhir kegiatan. Hasil rata-rata yang diperoleh sebelum diberikan materi (pretest) adalah 78,75 dan hasil rata-rata setelah diberikan materi adalah 98,25. Hasil dari kegiatan promosi kesehatan dengan metode ceramah ini sangat bermanfaat diberikan kepada pasien yang berobat ke Puskesmas Liang Anggang. Kegiatan ini memberikan dampak yang baik pada pasien, yakni terjadi peningkatan pengetahuan tentang cara menggunakan oralit dan zink saat diare. Hal ini dibuktikan dengan adanya peningkatan nilai pengetahuan pasien terhadap cara penggunaan oralit dan zink. Kata Kunci: Promosi Kesehatan, Puskesmas, Pengetahuan, Leaflet Diarrhea is a condition in which liquid bowel movements occur more than 3 times a day. Generally, diarrhea can occur due to consuming food and drinks contaminated with viruses, bacteria or parasites, malabsorption, allergies, poisoning, immunodeficiency, intoxication, and other causes. The purpose of this health promotion activity is to provide knowledge and information about the use of oralit and zink during diarrhea. The implementation of this health promotion was carried out by giving a pretest at the beginning of the activity followed by a lecture method along with media in the form of leaflets and a posttest at the end of the activity. The average result obtained before being given the material (pretest) was 78.75 and the average result after being given the material was 98.25. The results of health promotion activities using the lecture method are very useful given to patients who seek treatment at Puskesmas Liang Anggang. This activity has a good impact on patients, knowledge and understanding of how to use oralit and zink during diarrhea. This is evidenced by an increase in the patient's knowledge of how to use oralit and zink.
PENINGKATAN KEPUASAN KONSUMEN MELALUI KUALITAS PELAYANAN DAN HARGA
Authors: Riansyah  , Endang Silaningsih  , Andari Titiek Tjahja 
Published: March 2024

Perusahaan pada bidang pengendalian hama sudah banyak terdapat di jabodetabek, salah satunya bisnis dibidang jasa pengendalian hama. Banyaknya jumlah jasa pengendalian hama mengakibatkan peningkatan dengan jumlah usaha yang bersifat sejenis menyebabkan persaingan yang semakin ketat. Strategi yang dapat dilakukan untuk memenangkan persaingan adalah memberikan kepuasan bagi konsumen. Faktor yang berperan penting dalam menciptakan kepuasan konsumen diantaranya adalah kualitas pelayanan dan harga. Penelitian ini bertujuan untuk mengetahui pengaruh kualitas pelayanan dan harga secara simultan dan parsial terhadap kepuasan konsumen pada PT. Lasturi Karya Jasa Depok. Subjek dari penelitian ini adalah konsumen PT. Lasturi Karya Jasa sebanyak 60 konsumen sebagai anggota sampel. Bentuk penelitian ini adalah deskriptif dan verifikatif. Prosedur pengumpulan data dalam penelitian ini menggunakan dokumentasi, studi Pustaka dan penyebaran kuesioner. Metode analisis data yang digunakan adalah analisis regresi linear berganda. Hasil penelitian menunjukkan bahwa kualitas pelayanan dan harga dengan kriteria

baik. Secara simultan dan parsial kualitas pelayanan dan harga berpengaruh positif dan signifikan terhadap kepuasan konsumen.
Bacteria Mediated Uranium Species Transformation and Immobilization Mechanism in a Phosphate-rich System
Authors: Tan Wen-fa , Deng Zhi-Wen , Lv Jun-wen , Tang Dong-shan , Li Jia-xiang , Pang Chao 
Published: March 2024

Abstract
Uranium tailings without reliable anti-seepage treatment in the early years of mining and metallurgy has become a potential source of pollution. This work sought to explore the transformation and mechanism of uranium species in a bacteria and phosphate coexist system. The results showed that addition of phosphate enhanced uranium removal rate greatly in solution with the highest removal rate of 99.84%. Likewise, BCR finding displayed that residual phase in sediment samples of phytic acid group and nano-hydroxyapatite group was much higher than that of control group. XRD/SEM-EDS analyses revealed that the fugitive positions of phosphorus and uranium elements remain essentially the same on the sediment surface in the groundwater-sediment system, the appearance of more pronounced phosphorus and uranium signal peaks confirmed more U-P precipitates. Combined with XPS and BCR results, very interesting, phosphate could be complexed with hexavalent uranium to form a stable precipitate. This, to some extent, do not seem to support the view that tetravalent uranium is only stable state under reducing conditions. From this point of view, it demonstrates that bacteria can effectively mediated U-P precipitates. This also provides theoretical evidence that it succeeds efficiently in realizing the transformation of uranium from a transferable phase to a stable phase, which has a potential application value to groundwater in uranium mining areas.
Temporal relationship between symptom cluster and quality of life in rectal cancer survivor
Authors: You Chaoxiang , Xie Guiqiong , Jia Mengying , Li Shuang , Zhou Yi , Zhang Xiaoxuan , Wu Xiufei , Kou Hongyan 
Published: March 2024

Abstract

Symptom cluster and quality of life are negatively associated, but the prospective inter-relationship between them were unknown,which may provide a mechanism insight for symptom cluster management. A longitudinal study was conducted among 140 patients who undergoing laparoscopic-assisted sphincter-preserving surgery for rectal cancer between 2021 to 2022. We investigated the longitudinal associations of the change of symptom cluster with the trajectories of quality of life. These patients were assessed for symptom clusters and quality of life at specific time points: 2 weeks (T1), 1 month (T2), 3 months (T3) ,and 6 months (T4) after their surgeries. In our Pearson correlation analysis, the quality of life within 6 months after surgery showed a moderate-to-strong strength correlation (r=0.27-0.66) between the quality of life within the first 6 months post-surgery. There was also a significantly negative correlation between each symptom cluster and the quality of life at all four time points. Our cross-lagged model revealed a unidirectional temporal relationship between quality of life and symptom cluster. the quality of life level at these four time points could significantly and negatively predict the severity of each symptom cluster, with no observed reverse path. Importantly, the cross-lagged path coefficient from quality of life to symptom cluster was notably greater than the coefficient from symptom cluster to quality of life. These findings provide evidence that lower quality of life precede higher symptom cluster severity in rectal cancer survivor. This temporal relationship begins early in the post-surgery period, highlighting the importance of early quality of life intervention to help patients improve their symptom clusters. Keywords:rectal neoplasm;symptom cluster;quality of life;bidirectional relationship
Cannabidiol or ketamine for preventing the impact of adolescent early drug initiation on voluntary ethanol consumption in adulthood
Authors: Garcia-Fuster M. Julia , Colom-Rocha Carles , Bis-Humbert Cristian 
Published: March 2024

Abstract

Few studies have previously evaluated the long-term impact of initiating the combined use of alcohol and cocaine early-in-life during adolescence. Our preclinical study characterized changes in affective-like behavior and/or voluntary ethanol consumption emerging later on in adulthood during withdrawal and induced by adolescent drug exposure, as well as tested therapeutical interventions (i.e., cannabidiol or ketamine) to prevent the observed effects. We performed 3 independent studies with male and female Sprague-Dawley rats, treated in adolescence (postnatal days, PND 29–38) with ethanol, cocaine, their combination or vehicle. Following prolonged forced-withdrawal, adult rats were (1) scored for their affective-like state (forced-swim, elevated-plus maze, novelty-suppressed feeding, sucrose preference), (2) allowed to freely drink ethanol for 6 weeks (two-bottle choice), or (3) treated with cannabidiol or ketamine before given access to ethanol in adulthood. The results proved no signs of increased negative affect during withdrawal in adulthood following the adolescent treatments. However, adolescent ethanol exposure was a risk-factor for later developing an increased voluntary ethanol consumption in adulthood, both for male and female rats. This risk was similar when ethanol was combined with adolescent cocaine exposure, since cocaine alone showed no effects on later ethanol intake. Finally, rats exposed to adolescent ethanol and pretreated during forced-withdrawal with cannabidiol (and/or ketamine, but just for females) reduced ethanol voluntary consumption in adulthood. Our data provided two therapeutical options capable of preventing the impact of an early drug initiation during adolescence by decreasing voluntary ethanol consumption in adult rats.
Refining Environmental Behavior: The Impact of Framing Effects in News Propaganda on Chinese Farmers' Inclination to Engage in Waste Classification
Authors: Tian Qian , Zheng Nana , Ye Shuqi , Wang Shengcong 
Published: March 2024

Abstract

With 491 million farmers in China playing a crucial role in ecological governance, it is imperative for public institutions to guide them towards waste classification and foster a green lifestyle through policy interventions. This study conducted 300 questionnaire experiments across three counties in Shanxi and employed the Mann-Whitney U test to uncover the framing effect in news propaganda. Additionally, a moderated matching model was constructed to analyze the specific mechanisms at play. The findings indicate that the framing of news propaganda significantly impacts farmers' inclination to engage in waste classification, with a notable moderating effect between farmers' orientations and message framing. The study concludes by highlighting the potential of behavioral public policy in managing social risks, strengthening social cohesion, and fostering innovation in the social governance system.
Nutritional quality and functional properties of finger millet, sweet potato, and soybean composite flour as affected by blending ratios
Authors: Mohammed Ibrahim , Forsido Sirawdink Fikreyesus , Kuyu Chala G. 
Published: March 2024

Abstract
Despite their low nutritional values, cereals are the main raw materials that are used for the development of different food products. This study aimed to develop nutrient-rich flour blended from orange-fleshed sweet potato, finger millet, and soybean. The experiment was conducted to optimize the blending ratio of composite flours. Thirteen formulations of composite flours were generated using a mixture design with varying ratios of finger millet (45–55%), OFSP (30–40%), and soybean (10–20%). The composite flours' physical, functional, and nutritional properties were evaluated. The data were analyzed using Design Expert software version 13. The statistical analysis showed significant (P < 0.05) variations in protein, ash, carbohydrate, beta-carotene, bulk density, water absorption index, and water solubility index of the composite flours. Graphical optimization was used to determine the optimum values for each variable, resulting in 16% protein, 3.31% ash, 64.27% carbohydrate, 7.908mg/100g beta-carotene, 0.7g/ml bulk density, 2.78g/g WAI, and 15.95% WSI, in a blend of 47.46% finger millet, 34.54% orange-fleshed sweet potato, and 17.99% soybean flours. This study demonstrated that incorporating orange-fleshed sweet potato and soybean flour into composite flours significantly increased their nutritional value. These findings suggest that optimizing the blending ratio of composite flours can lead to nutrient-rich flour development with desirable nutritional and functional properties.
Time to Blindness and its associated risk factors of glaucoma patients Using Bayesian Survival Model: A data from Felege Hiwot Specialized Hospital, Ethiopia
Authors: YISMAW MINILIK DERSEH 
Published: March 2024

Abstract
Background: Glaucoma is a neurodegenerative condition that affects the eye and is associated with increased intraocular pressure. Intraocular pressure is carefully regulated and disturbance is often involved in the development of pathologies such as glaucoma, uveitis, and retinal detachment. The study identified factors that have an association with longitudinal IOP and time in glaucoma patients attending an ophthalmology clinic at the Felege Hiwot Comprehensive Specialised Hospital, Ethiopia using Bayesian survival model analysis.
Methods: A time-to-event study with data obtained from Felege Hiwot Comprehensive Specialized Hospital, glaucoma patients enrolled in an ophthalmology clinic, the measurement of IOP change approximately every six months and the time of an event occurring were taken. Study subjects were enrolled between the 1 January 2016 and 1st January 2020 period. A total of 328 patients were selected for this study. The Bayesian Weibull proportional hazard model for the survival data analysis was used.
Results: 328 patients were included in the analysis, with 2 being the minimum and 9 being the maximum for repeated measurements of IOP change, including the baseline. The hazard function of the Bayesian Weibull PH model is significantly determined by covariates such as age, blood pressure, diabetes, Pilocarpin, Timolol with Pilocarpin, Timolol with Diamox, Timolol with Diamox with Pilocarpin, medium treatment duration, long treatment duration, and advanced stage of glaucoma in patients.
Conclusion: Based on the Bayesian Weibull PH model, the predictors of age CI (0.2691, 0.4919), blood pressure (0.9148, 0.8017), diabetic disease (0.1015, 0.1943), long treatment duration (0.2326, 0.4437), advanced stages of glaucoma (0.1099, 1.328), and cup-disk ratio>0.7 (-0.159, -0.015) were significantly affect the average intraocular pressure (IOP). Also, the predictor type of medication was statistically significant and negatively associated with the responses to IOP.
Recommendation: Health professionals give more attention to the type of medication especially (Timolol with Pilocarpin, Timolol with Diamox, and Timolol with Diamox with Pilocarpin), to minimize intraocular pressure when the patients are back again in the hospital.
Experimental Study on Formability in Electrohydraulic Forming with and without Bridging Wire
Authors: Jang Yoonho , Kim Minseok , Kim Jeong 
Published: March 2024

Abstract
Electrohydraulic forming (EHF) can overcome the shortcomings of deep drawing and electromagnetic forming, demonstrating a reduced bouncing effect, formation in narrow areas, and no effect on the electrical conductivity of the blank. In existing EHF experiments, wires are fastened to provide a forming force at variable positions. Therefore, production of uniform products is difficult, and the experimentation is time-consuming and difficult to apply in industrial processes.
In this study, wireless and wire-cross EHF were presented to reduce the time required for EHF experiments and produce a uniform forming force. The maximum forming height and formability were evaluated using a 0.5 t SUS430 specimen and free-bulging die. The required experimentation time was measured by comparing each EHF with a conventional EHF.
The wireless EHF experiments required the least time and produced a constant forming force. A wire-cross EHF was proposed to compensate for the time required to connect the fully connected wires in a conventional EHF. However, this did not substantially reduce the experiment time. Although wire-cross EHF has a higher energy efficiency than wireless EHF because wires are incorporated, it cannot completely overcome the fundamental problems of EHF.
In wireless EHF, two consecutive experiments were performed to produce the same height under an applied voltage of 6 kV. When conducting consecutive experiments, if the experiment is ready for the first time, only the capacitor must be repeatedly charged and discharged while maintaining a constant electrode spacing, so the experiment can be completed faster.
Dielectrophoretic characterization of peroxidized retinal pigment epithelial cells as a model of age-related macular degeneration
Authors: Yadav Dharm Singh , Tivig Ioan , Savopol Tudor , Moisescu Mihaela G. 
Published: March 2024

Abstract

Age-related macular degeneration (AMD) is a prevalent ocular pathology affecting mostly the elderly population. AMD is characterized by a progressive retinal pigment epithelial (RPE) cell degeneration, mainly caused by an impaired antioxidative defense. One of the AMD therapeutic procedures is injecting healthy RPE cells into the subretinal space. For this purpose, there is a need for pure, healthy RPE cell suspensions. In this article, we present an experimental approach to electrically characterize RPE cells, aiming to demonstrate the possibility of separating healthy RPE cells from a mixture of healthy/oxidized cells by dielectrophoresis. In order to find out the relevant conditions to create an in-vitro AMD cellular model, BPEI-1 rat RPE cells were exposed to hydrogen peroxide and evaluated in terms of cell viability by various methods (microscopic imaging, impedance-based real-time cell analysis, MTS assay). Then, healthy and oxidized cells were characterized by recording their dielectrophoretic spectra, based on which electric cell parameters (crossover frequency, membrane conductivity and permittivity, and cytoplasm conductivity) were computed. A COMSOL simulation was performed on a theoretical microfluidic-based dielectrophoretic separation chip using these parameters. By increasing the hydrogen peroxide concentration, we found that the first crossover frequency was shifted toward lower values, and the cell membrane permittivity progressively increased. These changes were attributed to progressive membrane peroxidation since they were diminished when measured on cells treated with the antioxidant N-acetylcysteine. Moreover, the changes in the crossover frequency showed to be enough for the healthy cells to be efficiently separated, as demonstrated by simulations.
Examining patient choice and provider competition under the National Health Insurance Fund outpatient cover in Kenya: Does it enhance access and quality of care?
Authors: Kazungu Jacob , Barasa Edwine , Quaife Matthew , Nonvignon Justice 
Published: March 2024

Abstract

Background
While patient choice and provider competition are predicted to influence provider behaviour for enhancing access and quality of care, evidence on provider perceptions and response to patient choice and provider competition is largely missing in low-resource settings such as Kenya. We examined provider and purchaser perceptions about whether patient choice and provider competition influenced provider behaviour and enhanced access and quality of outpatient care in Kenya.
Methods
We conducted a qualitative study to explore this across two purposefully selected counties in Kenya. We conducted 15 in-depth interviews (IDIs) with health facility managers and National Health Insurance Fund (NHIF) staff across the two counties. We examined these across five areas summarised as either local market conditions or patient feedback following the Vengberg framework.
Results
We found that NHIF members’ choice of outpatient facilities compelled private and faith-based providers to compete for members while public providers did not view choice as a way of spurring competition. Besides, all providers did not receive any information regarding the exit of NHIF members from their facilities. Providers felt that that information would be crucial for their planning, especially in enhancing service accessibility and quality of care. Most providers ensured the availability of drugs, provided a wider range of services and leveraged on marketing to attract and retain NHIF members. Finally, providers highlighted their redesign of service delivery to meet NHIF members’ needs (access) whilst enhancing the quality-of-care aspects such as waiting time and having qualified health workers.
Conclusion
There is a need for NHIF to share NHIF members’ exit information with providers to support their service delivery arrangements in response to NHIF members’ needs. Besides, this study contributes evidence on patient choice and provider competition and their influence on access and quality of care from a low-resource setting country.
Transcriptomic analysis of TGFβ-mediated fibrosis in primary human Tenon’s fibroblasts
Authors: Pasvanis Zoe , Boynes Antony , Kong Roy C.K. , Chan Elsa C. , Wong Raymond C.B. , Gaskin Jennifer Fan 
Published: March 2024

Abstract

Glaucoma filtration surgery (GFS) is performed to slow down disease progression in glaucoma, a leading cause of irreversible blindness worldwide. Following surgery, pathological wound healing may lead to conjunctival fibrosis and filtering failure. Myofibroblasts are the key cells responsible for postoperative conjunctival scarring. This study aims to further understand the molecular mechanisms of conjunctival fibrosis following GFS. We utilised RNA-sequencing (RNA-seq) to delineate the TGFβ1 induced changes in the transcriptome of human Tenon’s fibroblasts (HTFs). RNA sequencing was performed on HTFs after 5 days of TGFβ1 treatment. Following quality control, 3,362 differentially expressed genes were identified, of which 1,532 were upregulated and 1,820 were downregulated. We identified signaling pathways associated with the pathogenesis of conjunctival fibrosis. The DEGs (differentially expressed genes) were enriched in pathways including myofibroblast differentiation, TGFβ-signaling, collagen and extracellular matrix organization, epithelial to mesenchymal transition, and cell cycle regulation. The results of this study identified the transition from HTF to myofibroblast is characterised by the upregulation of key genes including LDLRAD4, CDKN2B, FZD8, MYOZ1, and the downregulation of SOD3, LTBP4 and RCAN2. This insight into the transcriptional landscape of HTFs and myofibroblast differentiation is essential to understand the pathophysiology of conjunctival scarring and develop new therapeutic agents.
Study on the motion characteristics of a single droplet impacting stationary wall based on the pseudopotential MRT-LBM model
Authors: Wang weishu , Li chuan , Wang jie 
Published: March 2024

Abstract
The MRT-LBM pseudopotential model with large density ratio with adjustable surface tension was used to simulate the motion process of single droplet hitting the stationary wall, and the influence of Reynolds number, Weber number and Bond number on the motion characteristics of the droplet was analyzed. The accuracy of the model is verified from multiple angles. The results show that the increase of Reynolds number and Weber number is conducive to the increase of droplet spreading diameter, maximum spreading factor and dimensionless height in the droplet spreading stage, the difference is that the increase of Reynolds number and Weber number leads to the increase of droplet spreading time, while the increase of Bond number cannot change the droplet spreading time. During the movement of the droplet, Webb counts too little, and "ring-shaped" droplets appear in the droplet retraction stage, and Webb counts too little, and the droplets cannot be retracted after spreading, but directly fragment into small droplets.