bluuebunny/crossref_metadata_2025_split huggingface dataset:
An adjective list for assessing emotional expressivity in psychotherapy research
Authors: Leising Daniel , Müller Jochen , Hahn Christina 
Published: September 2007

AbstractBackground: Several forms of psychotherapy aim at improving their patients' emotional expressivity, which is considered to contribute to mental health. Studies on the success of such attempts are virtually absent. Aim: To develop a measure for assessing changes of emotional expressivity in the course of psychotherapy. Method: In study 1 (N = 321), we generated a pool of German adjectives referring to emotional expressivity and reduced the number of those adjectives by means of factor‐analysis. In study 2 (N = 103), we determined how emotional expressivity is related to the Big Five personality factors. Results: An expressivity scale of 12 items with highly satisfactory psychometric properties was construed. Emotional expressivity is substantially related to Extraversion and moderately related to Agreeableness and Openness. Conclusion: The scale is ideally suited for repeated assessments in the course of psychotherapy in multi‐agent (e.g., inpatient) settings. Copyright © 2007 John Wiley & Sons, Ltd.
Ecocentric management: an update
Authors: Cunha Miguel Pina e , Rego Arménio , Vieira da Cunha João 
Published: September 2007

AbstractIn an article published in 1995, Paul Shrivastava coined the notion of an ecocentric management paradigm. The ecocentric paradigm provided an integrated and holistic view of the organization at peace with the natural environment. This paper updates the idea of ecocentricity and enriches it with facts and fears that have emerged since then. We suggest that Shrivastava's original formulation was an improvement of the industrial paradigm, advance an alternative reconceptualization of ecocentricity and discuss some of the possible obstacles to the emergence and adoption of ecocentric management. Copyright © 2007 John Wiley & Sons, Ltd and ERP Environment.
Supramolecular Chemistry of Acyclic Oligopyrroles
Authors: Maeda Hiromitsu 
Published: September 2007

AbstractAcyclic π‐conjugated oligopyrrole derivatives, though not extensively studied, often have more advantages as anion receptors and metal‐coordination ligands than their cyclic counterparts. This is due to the formation of versatile complexes and supramolecular assemblies, although they do require conformational changes by guest binding. Of the linear oligopyrroles, oligomeric derivatives of dipyrrins bridged by π‐conjugated spacers behave as building subunits and form coordination oligomers and discrete coordination nanorings. In contrast, pyrrole oligomers with hydrogen‐bond‐acceptor site(s) have yielded unique morphologies as supramolecular assemblies and micro‐ and nanometer‐scale structures by means of hydrogen‐bonding interactions. Furthermore, a new class of acyclic anion receptors, namely, BF2 complexes of dipyrrolyl diketones, has been shown to interact with anions by means of the pyrrole NH group and bridging CH interactions. Inversion of the pyrrole rings was found to be essential to capture anions by using these binding sites. Aryl substitution of the receptors as π‐extended derivatives has enabled the formation of assemblies such as supramolecular organogels that can be controlled by the addition of anions.(© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2007)
The Creolophins: A Family of Linear Triquinanes from Creolophus cirrhatus (Basidiomycete)
Authors: Opatz Till , Kolshorn Heinz , Birnbacher Judith , Schüffler Anja , Deininger Friederike , Anke Timm 
Published: September 2007

AbstractComplicatic acid and five novel linear triquinanes were isolated from mycelial cultures of Creolophus cirrhatus. The creolophins A, C, D, and E represent a novel type of highly oxidized triquinane sesquiterpenoids. Whereas those compounds with a secondary alcohol moiety in ring A are stable, the exomethylene ketone creolophin E (5) partly dimerized during workup to form the decacyclic 1,4‐dioxepin‐6‐one neocreolophin (6). Compounds 5 and 6 display cytotoxic activities against several tumor cell lines.(© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2007)
Asymmetric Synthesis of 1‐(2‐Pyrrolyl)alkylamines by the Addition of Organometallic Reagents to Chiral 2‐Pyrroleimines
Authors: Alvaro Giuseppe , Di Fabio Romano , Gualandi Andrea , Savoia Diego 
Published: September 2007

AbstractThe addition of organometallic (lithium, magnesium, zinc) reagents to 2‐pyrroleimines derived from (S)‐valinol and (S)‐phenylglycinol gave N‐substituted‐1‐(2‐pyrrolyl)alkylamines with high yields and diastereoselectivities. The (S,S)‐diastereomers were useful intermediates for the preparation of enantiopure 1‐[1‐(2‐pyrrolyl)alkyl]aziridines by routine cyclization of the β‐amino alcohol moiety and for the preparation of (S)‐N‐benzoyl 1‐[1‐(2‐pyrrolyl)alkyl]amines and their N‐substituted derivatives by oxidative cleavage of the chiral auxiliary. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2007)
Application of CE in hydrodynamically closed systems for analysis of bioactive compounds in food
Authors: Kvasnička František 
Published: September 2007

AbstractCE is a family of electrokinetic separation techniques that separate compounds based upon differences in electrophoretic mobilities, phase partitioning, pI, molecular size, or a combination of one or several of these properties. CE has been used in several modes to analyze and characterize a wide variety of analytes from simple inorganic ions, small organic molecules, peptides, proteins, nucleic acids to virus, microbes and particles. Food consists of a complex mixture of a variety of components, many of which are biologically active. Components classified as “nutrients” are essential for growth, maintenance, and repair of the body. Other food constituents, typically occurring in small quantities, are classified as “biologically active substances” and they have beneficial or harmful effects on human health. There are two types of biologically active substances in food – naturally occurring and food additives. The bioactive compounds of food that will be mentioned in this review are inorganic and organic acids, amino acids, vitamins, phenolic compounds, biogenic amines, antinutrients, toxins, etc. This review is focused on the application of CE with hydrodynamically closed system (suppression of EOF) for the analysis of the above‐mentioned compounds. CE can be an alternative method to HPLC or other methods for analysis of bioactive compounds in food. The main advantages of CE are low running cost (at least ten times than HPLC) and consideration to environment (hundreds of microliters of diluted water based electrolyte per analysis).
Determination of iodide in samples with complex matrices by hyphenation of capillary isotachophoresis and zone electrophoresis
Authors: Pantůčková Pavla , Urbánek Marek , Křivánková Ludmila 
Published: September 2007

AbstractA method has been developed for the determination of iodide in mineral water, seawater, cooking salt, serum, and urine based on hyphenation of capillary ITP and zone electrophoresis. A commercially available instrumentation for capillary ITP with column‐switching system was used. ITP served for removal of chloride present in the analyzed samples in a ratio of 106–107:1 to iodide, zone electrophoresis was used for evaluation. Isotachophoretic separation proceeded in a capillary made of fluorinated ethylene–propylene copolymer of 0.8 mm id and 90 mm total length to the bifurcation point filled with a leading electrolyte (LE) composed of 8 mM HCl + 16 mM β‐alanine (β‐Ala) + 10% PVP + 2.86 mM N2H4×2HCl, pH 3.2; and a terminating electrolyte composed of 8 mM H3PO4 + 16 mM β‐Ala + 10% PVP + 5 mM N2H4, pH 3.85 for all the matrices except seawater. For ITP of seawater the LE consisted of 50 mM HCl + 100 mM β‐Ala + 10% PVP + 2.86 mM N2H4×2HCl, pH 3.52. Distance of conductivity detector from the injection point and bifurcation point was 52 and 38 mm, respectively. Zone electrophoresis was performed in a capillary made of fused silica of 0.3 mm id and 160 mm total length filled with LE from isotachophoretic step. LODs reached for all matrices were 2–3×10−8 M concentration (2.5–4 μg/L) enabled monitoring of iodide in all analyzed samples with RSD 0.4–9.3%. Estimated concentrations of iodide in individual matrices were 10−6–10−8 M.
Determination of association constants between steroid compounds and albumins by partial‐filling ACE
Authors: Amundsen Lotta K. , Sirén Heli 
Published: September 2007

AbstractACE is a popular technique for evaluating association constants between drugs and proteins. However, ACE has not previously been applied to study the association between electrically neutral biomolecules and plasma proteins. We studied the affinity between human and bovine serum albumins (HSA and BSA, respectively) and three neutral endogenous steroid hormones (testosterone, epitestosterone and androstenedione) and two synthetic analogues (methyltestosterone and fluoxymesterone) by applying the partial‐filling technique in ACE (PF‐ACE). From the endocrinological point of view, the distribution of endogenous steroids among plasma components is of great interest. Strong interactions with albumins suppress the biological activity of steroids. Notable differences in the association constants were observed. In the case of the endogenous steroids, the interactions between testosterone and the albumins were strongest, and those between androstenedione and the albumins were substantially weaker. The association constants, Kb, for testosterone, epitestosterone and androstenedione and HSA at 37°C were 32 100 ± 3600, 21 600 ± 1500 and 13 300 ± 1300 M−1, respectively, while the corresponding values for the steroids and BSA were 18 800 ± 1500, 14 000 ± 400 and 7800 ± 900 M−1. Methyltestosterone was bound even more strongly than testosterone, while fluoxymesterone was only weakly bound by the albumins. Finally, the steroids were separated by PF‐ACE with HSA and BSA used as resolving components.
Modelling of forecast errors in geophysical fluid flows
Authors: Bannister R. N. , Katz D. , Cullen M. J. P. , Lawless A. S. , Nichols N. K. 
Published: September 2007

AbstractA method is sought to decompose errors in numerical forecasts of the atmosphere into components that are uncorrelated. This can simplify the representation of the probability density function of forecast errors so that it can be used in data assimilation. A new method based on potential vorticity (PV) is used to partition errors into balanced and unbalanced variables that are thought to be mutually uncorrelated. The effectiveness of the PV method is compared with a simpler method. A toy model and an operational forecasting model are used to show that the PV‐based variables are usually less correlated than those of the simpler approach. Copyright © 2007 John Wiley & Sons, Ltd.
On transferability of genome‐wide tagSNPs
Authors: Gu C. Charles , Yu K. , Ketkar S. , Templeton Alan R. , Rao D.C. 
Published: September 2007

AbstractThe question of tagging single nucleotide polymorphism (tagSNP) transferability is an important one because many ongoing and upcoming Genome‐Wide Association studies rely critically upon the validity, and practical feasibility of using a universal core set of tagSNPs. A series of recent studies analyzed performance of tagSNPs selected based on the HapMap. While these studies showed largely satisfactory transferability of the tagSNPs, they also reported that the level of transferability varies, substantively sometimes, especially when tagSNPs selected in one population were used in another distant population. We present a review of the literature about where and why tagSNP transferability may become a problem and suggest research directions that may help the resolution. Genet. Epidemiol. 2008. © 2007 Wiley‐Liss, Inc.
Sparse source imaging in electroencephalography with accurate field modeling
Authors: Ding Lei , He Bin 
Published: September 2007

AbstractWe have developed a new L1‐norm based generalized minimum norm estimate (GMNE) and have fully characterized the concept of sparseness regularization inherited in the proposed algorithm, which is termed as sparse source imaging (SSI). The new SSI algorithm corrects inaccurate source field modeling in previously reported L1‐norm GMNEs and proposes that sparseness a priori should only be applied to the regularization term, not to the data term in the formulation of the regularized inverse problem. A new solver to the newly developed SSI has been adopted and known as the second‐order cone programming. The new SSI is assessed by a series of simulations and then evaluated using somatosensory evoked potential (SEP) data with both scalp and subdural recordings in a human subject. The performance of SSI is compared with other L1‐norm GMNEs and L2‐norm GMNEs using three evaluation metrics, i.e., localization error, orientation error, and strength percentage. The present simulation results indicate that the new SSI has significantly improved performance in all evaluation metrics, especially in the metric of orientation error. L2‐norm GMNEs show large orientation errors because of the smooth regularization. The previously reported L1‐norm GMNEs show large orientation errors due to the inaccurate source field modeling. The SEP source imaging results indicate that SSI has the best accuracy in the prediction of subdural potential field as validated by direct subdural recordings. The new SSI algorithm is also applicable to MEG source imaging. Hum Brain Mapp 2008. © 2007 Wiley‐Liss, Inc.
Impact of weight-based ribavirin with peginterferon alfa-2b in african americans with hepatitis C virus genotype 1
Authors: Jacobson Ira M. , Brown Robert S. , McCone Jonathan , Black Martin , Albert Clive , Dragutsky Michael S. , Siddiqui Firdous A. , Hargrave Thomas , Kwo Paul Y. , Lambiase Louis , Galler Greg W. , Araya Victor , Freilich Bradley , Harvey Joann , Griffel Louis H. , Brass Clifford A. 
Published: September 2007

Abstract

WIN-R (
W
eight-based dosing of peg
IN
terferon alfa-2b and
R
ibavirin) was a multicenter, randomized, open-label, investigator-initiated trial involving 236 community and academic sites in the United States, comparing response to pegylated interferon (PEG-IFN) alfa-2b plus a flat or weight-based dose of ribavirin (RBV) in treatment-naive patients with chronic hepatitis C and compensated liver disease. Patients were randomized to receive PEG-IFN alfa-2b at 1.5 μg/kg/week plus flat-dose (800 mg/day) or weight-based-dose RBV (800 mg/day for weight <65 kg, 1000 mg/day for 65-85 kg, 1200 mg/day for >85-105 kg, or 1400 mg/day for >105-<125 kg). Sustained virologic response (SVR; undetectable [<125 IU/mL] hepatitis C virus [HCV] RNA at end of follow-up) in patients ≥65 kg was the primary end point. Low SVR rates have been reported among African American individuals, in whom there is a preponderance of HCV genotype 1. This subanalysis of WIN-R was conducted to evaluate the efficacy of weight-based dosing among African American individuals with genotype 1 infection enrolled in the trial. Of 362 African American patients in the primary efficacy analysis, 188 received RBV flat dosing and 174 received weight-based dosing. SVR rates were higher (21% versus 10%;

P

= 0.0006) and relapse rates were lower (22% versus 30%) in the weight-based-dose group than in the flat-dose group. Safety and rates of drug discontinuation were similar between the 2 groups.

Conclusion:

Weight-based dosing of RBV is more effective than flat dosing in combination with PEG-IFN alfa-2b in African American individuals with HCV genotype 1. Even with weight-based dosing, response rates in African American individuals are lower than reported in other ethnic groups. (HEPATOLOGY 2007.)
Preparation of the β3‐Homoselenocysteine Derivatives Fmoc‐β3hSec(PMB)‐OH and Boc‐β3hSec(PMB)‐OH for Solution and Solid‐Phase‐Peptide Synthesis and Selenoligation
Authors: Flögel Oliver , Casi Giulio , Hilvert Donald , Seebach Dieter 
Published: September 2007

AbstractThe title compounds, 4 and 7, have been prepared from the corresponding α‐amino acid derivative selenocystine (1) by the following sequence of steps: cleavage of the SeSe bond with NaBH4, p‐methoxybenzyl (PMB) protection of the SeH group, Fmoc or Boc protection at the N‐atom and Arndt–Eistert homologation (Schemes 1 and 2). A β3‐heptapeptide 8 with an N‐terminal β3‐hSec(PMB) residue was synthesized on Rink amide AM resin and deprotected (‘in air’) to give the corresponding diselenide 9, which, in turn, was coupled with a β3‐tetrapeptide thiol ester 10 by a seleno‐ligation. The product β3‐undecapeptide was identified as its diselenide and its mixed selenosulfide with thiophenol (Scheme 3). The differences between α‐ and β‐Sec derivatives are discussed.
Site‐Specific Acid–Base Properties of Tenoxicam
Authors: Kóczián Kristóf , Völgyi Gergely , Kökösi József , Noszál Béla 
Published: September 2007

AbstractThe Hammett approach, as a new deductive tool, was introduced to characterize the otherwise inaccessible minor protonation pathway of tenoxicam (1), the non‐steroidal anti‐inflammatory drug. A total of eight compounds, constituting a systematic series of side chain‐substituted analogues of tenoxicam and piroxicam (2), were synthesized and studied in terms of acidbase properties and Hammett constants to identify the ideal replacement of the unprotonated pyridin‐2‐yl group, a key moiety in both molecules. Hammett constants of the phenyl substituents have been found to be in a linear correlation with the experimental log K values of the enolate sites, the basic moiety of the extended conjugated system in this family of piroxicam derivatives. Then, a similar correlation was observed for the analogous tenoxicam derivatives. After identifying the 2‐aza Hammett constant of the pyridin‐2‐yl group and the corresponding log K value, the site‐specific acid–base properties of tenoxicam could be quantitated. This novel method is assessed to be a fine‐tuning tool to find the ideal substituent by using analogue‐based deductive method to obtain site‐specific constants of the minor protonation/deprotonation pathway in drugs and biomolecules. The tenoxicam microconstant values indicate that the enolate moiety is of extremely low basicity (reflected by the $ \log \it k^{\rm{O}} $=3.70 and $ \log \it k_{\rm{N}}^{\rm{O}} $=1.09 values), which can, however, be interpreted in terms of the peculiar ring system and the overwhelming electron‐withdrawing effects of the adjacent heteroatoms. A diagram depicting the pH‐dependent distribution of 1 microspecies is also presented.
Myricananone and Myricananadiol: Two New Cyclic ‘Diarylheptanoids’ from the Roots of Myrica nana
Authors: Yu Ya‐Fang , Lu Qing , Guo Li , Mei Ren‐Qiang , Liang Heng‐Xing , Luo Du‐Qiang , Cheng Yong‐Xian 
Published: September 2007

AbstractTwo new cyclic ‘diarylheptanoids’, myricananone (1) and myricananadiol (2), were isolated from the roots of Myrica nana, together with the known compounds myricanol (3), myricanone (4), and porson (5). Their structures were determined by spectroscopic methods, including 1D‐ and 2D‐NMR as well as HR‐ESI‐MS analyses.
Chiral Recognition of Zolmitriptan by Modified Cyclodextrins
Authors: Kumar Vydyula Pavan , Kumar Perepogu Arun , Suryanarayana Iragavarapu , Nageswar Yadavalli Venkata Durga , Rao Kakulapati Rama 
Published: September 2007

AbstractThe two pyrrolidinylidenesulfamido‐modified β‐cyclodextrins (β‐CDs) 3 and 4 were prepared and studied for chiral discrimination of the enantiomers (R)‐ and (S)‐1 of zolmitriptan. The pyrrolidinylidenesulfamido spacer improved the chiral discrimination and binding abilities of these modified cyclodextrins. The hosts 3 and 4 showed higher selectivity for (S)‐1. The association constants (Table) and enantioselectivity factors were calculated for the complexes of (R)‐ and (S)‐1 with the β‐CDs 2–4. The formation of host⋅guest complexes was confirmed by 1H‐NMR studies.
Experimental and Density‐Functional‐Theory (DFT) Studies on the DNA‐Binding Trend and Spectral Properties of the Ruthenium Complexes [Ru(4,7‐dmp)(bdip)]2+ and [Ru(bpy)2(bdip)]2+ (4,7‐dmp=4,7‐Dimethyl‐1,10‐phenanthroline, bdip=2‐(1,3‐Benzodioxol‐4‐yl)‐1H‐imidazo[4,5‐f] [1,10]phenanthroline, bpy=2,2′‐bipyridine)
Authors: Tan Li‐Feng , Zhang Sheng , Chao Hui , Zheng Kang‐Cheng , Wang Fang , Xiao Yue , Ji Liang‐Nian 
Published: September 2007

AbstractThe new ligand bdip (=2‐(1,3‐benzodioxol‐4‐yl)‐1H‐imidazo[4,5‐f][1,10]phenanthroline) and its RuII complexes [Ru(4,7‐dmp)2(bdip)]2+ (1; 4,7‐dmp=4,7‐dimethyl‐1,10‐phenanthroline) and [Ru(bpy)2(bdip)]2+ (2; bpy=2,2′‐bipyridine) were synthesized and characterized by elemental analysis, MS, 1H‐NMR, and cyclic voltammetry. The DNA‐binding properties of 1 and 2 to calf‐thymus DNA (CT‐DNA) were investigated by different spectrophotometric methods and viscosity measurements as well as by equilibrium dialysis and circular‐dichroism (CD) spectroscopy. The results suggest that both complexes bind to DNA through intercalation, and that the ancillary ligands of (polypyridine)ruthenium(II) complexes have significant effects on the spectral properties and DNA‐binding behavior of the complexes. Theoretical studies for these complexes were also carried out by the density‐functional‐theory (DFT) method. The trend in the DNA‐binding affinity and some electrochemical and spectral properties of the complexes were confirmed by the DFT calculations.
Estimation of seasonal crop water consumption in a vineyard using Bowen ratio‐energy balance method
Authors: Zhang B. Z. , Kang S. Z. , Zhang L. , Du T. S. , Li S. E , Yang X. Y. 
Published: September 2007

AbstractInformation about seasonal crop water consumption is useful to develop the appropriate irrigation scheme. Measurements of energy balance components using the Bowen ratio method were made for a complete growing season at a vineyard in the arid region of northwest China. Vine in the experiment was furrow‐irrigated using a trellis system. The measured evapotranspiration was compared with estimates using the soil water balance method. It is shown that the Bowen ratio method provided accurate estimates of evapotranspiration from the vineyard and this requires that the Bowen ratio system is appropriately installed. The energy balance components showed typical diurnal pattern with peaks that occurred around the midday, except for the ground heat flux which delayed its peak by 2–3 h. The sensible heat flux was greater than the latent heat flux and followed the net radiation closely. The ratio of the latent heat flux to net radiation was low in the early growing season and increased over time. Under the limited irrigation experienced in the vineyard, the latent heat flux was controlled by available soil moisture and the total evapotranspiration in the growing season was 253 mm. The seasonal progression of the crop coefficient is similar to that reported in the literature, with the maximum occurring during the month of September. The crop coefficient can be estimated as a non‐linear function of day of year (DOY) and used to estimate evapotranspiration from vineyards in the region. Copyright © 2007 John Wiley & Sons, Ltd.