bluuebunny/crossref_metadata_2025_split huggingface dataset:
Papillae, psammoma bodies, and/or many nuclear pseudoinclusions are helpful criteria but should not be required for a definitive cytologic diagnosis of papillary thyroid carcinoma: An institutional experience of 207 cases with surgical follow up
Authors: Elsheikh Tarik M. , Thomas Matthew , Brainard Jennifer , Di Marco Jessica , Manosky Erica , Springer Bridgette , Underwood Dawn , Chute Deborah J. 
Published: April 2024

AbstractBackgroundNoninvasive follicular thyroid neoplasm with papillary‐like features (NIFTP) was introduced in 2016 replacing noninvasive follicular variant of papillary thyroid carcinoma, with recommendations to label them “noncancer.” To avoid reducing risk of malignancy (ROM) and overdiagnosing NIFTP as malignant, some authors required restricted cytologic criteria (RC) for a definitive diagnosis of papillary thyroid carcinoma (PTC), including papillae, psammoma bodies. or ≥3 nuclear pseudoinclusions. Since then, NIFTP criteria have been revised, biologic behavior better understood, and incidence reported to be much lower than initially anticipated. This study examines the impact of RC on PTC cytologic diagnoses, ROM, and detection of clinically significant carcinomas (CSC).Materials and MethodsA total of 207 thyroid FNAs originally diagnosed as PTC and suspicious for PTC (SPTC) with surgical follow‐up were evaluated. RC were retrospectively applied to cases as a requirement for diagnosing PTC, and cases that did not meet RC were reclassified as SPTC. ROMs and diagnostic accuracies of pre‐ and post‐RC diagnoses were correlated with followup CSC.ResultsRC were met in 118/142 (83%) and 20/65 (31%) of cases originally diagnosed as PTC and SPTC, respectively. Post‐RC, 29% (19/65) of CSC originally diagnosed as SPTC were upgraded to PTC, and 17% (24/142) of CSC originally diagnosed as PTC were downgraded to SPTC. No NIFTPs were diagnosed as malignant.ConclusionsRC should not be required for a definitive diagnosis of PTC when other nuclear features of PTC are diffuse and overt. Applying RC, however, helps the pathologist arrive at a more definitive diagnosis of PTC in suspicious cases.
An ML‐based task clustering and placement using hybrid Jaya‐gray wolf optimization in fog‐cloud ecosystem
Authors: Keshri Rashmi , Vidyarthi Deo Prakash 
Published: April 2024

SummaryThe rapid expansion of IoT systems has caused network congestion and delays in task placement and resource provisioning as usually the tasks are executed at a far location in the cloud. Fog computing reduces the computing burden of cloud data centers as well as the communication burden of the internet as fog resources are placed near the data generation points. Within Fog computing, an important challenge is the optimal task placement which is an NP‐class problem. This work applies machine learning for task clustering and addresses the task placement problem in a fog computing environment using a hybrid of two recent metaheuristics; Jaya and gray wolf optimization (GWO). The hybrid method considers optimizing the total number of active fog nodes, load balancing in fog nodes, and average response time of the tasks. The performance of the proposed method is evaluated on a real‐time LCG dataset and is compared with reinforcement learning fog scheduling (RLFS), genetic algorithm (GA), dynamic resource allocation mechanism (DRAM), load balancing and scheduling algorithm (LBSSA), and particle swarm optimization with simulated annealing (PSO‐SA) algorithms. The results demonstrate the superiority of the suggested method over the baseline techniques in terms of average improvement of 51.04% in load balance variance, 30.25% in average response time, 24.16% in execution time, and 47.10% in the number of devices used.
Charge Relay Without Proton Transfer: Coupling of Two Short Hydrogen Bonds via Imidazole in Models of Catalytic Triad of Serine Protease Active Site
Authors: Tupikina Elena Yu. , Sigalov Mark V. , Alkhuder Omar , Tolstoy Peter M. 
Published: April 2024

AbstractA homologous series of 20 substituted alcohol‐imidazole‐acetate model complexes imitating the charge relay system in Ser‐His‐Asp catalytic triad of serine proteases is considered quantum‐chemically. We show qualitatively that the geometries of alcohol‐imidazole and imidazole‐acetate short hydrogen bonds are strongly coupled via the central imidazole and such complexes are capable of effectively relaying the charge from acetate to alcohol moiety upon relatively small concerted proton displacements. We hypothesize an alternative catalytic mechanism of serine proteases that does not require two complete proton transfers or hydrogen bond breakage between Ser and His residues.
On the realization of an amplifier‐tuned low/high frequency family of oscillators
Authors: Elwakil A. S. , Maundy B. J. , Psychalinos C. 
Published: April 2024

SummaryWe propose a family of equal‐R equal‐C dual amplifier oscillators with gain‐tunable start‐up condition and oscillation frequency. In particular, while one of the amplifiers can be used to satisfy the oscillator start‐up condition, the second amplifier can be used to tune the oscillation frequency. In this regard, it is observed that the oscillation frequency can be made very low or very high independent of the RC time constant of the circuit by properly choosing the amplifier gain and the circuit topology. In one possible topology, the oscillation frequency is directly proportional to the tuning amplifier gain, while in a second topology, it is inversely proportional to this gain. Both topologies generate two outputs which also have a gain‐tunable leading or lagging phase shift. Circuit simulations and experimental results are presented to verify the theory in addition to a non‐conventional application in chaos generation.
Effects of resource availability and interspecific interactions on Arctic and red foxes' winter use of ungulate carrion in the Fennoscandian low‐Arctic tundra
Authors: Lacombe Simon , Ims Rolf , Yoccoz Nigel , Kleiven Eivind Flittie , Nicolau Pedro G. , Ehrich Dorothee 
Published: April 2024

AbstractIn the Arctic tundra, predators face recurrent periods of food scarcity and often turn to ungulate carcasses as an alternative food source. As important and localized resource patches, carrion promotes co‐occurrence of different individuals, and its use by predators is likely to be affected by interspecific competition. We studied how interspecific competition and resource availability impact winter use of carrion by Arctic and red foxes in low Arctic Fennoscandia. We predicted that the presence of red foxes limits Arctic foxes' use of carrion, and that competition depends on the availability of other resources. We monitored Arctic and red fox presence at supp lied carrion using camera traps. From 2006 to 2021, between 16 and 20 cameras were active for 2 months in late winter (288 camera‐winters). Using a multi‐species dynamic occupancy model at a week‐to‐week scale, we evaluated the use of carrion by foxes while accounting for the presence of competitors, rodent availability, and supplemental feeding provided to Arctic foxes. Competition affected carrion use by increasing both species' probability to leave occupied carcasses between consecutive weeks. This increase was similar for the two species, suggesting symmetrical avoidance. Increased rodent abundance was associated with a higher probability of colonizing carrion sites for both species. For Arctic foxes, however, this increase was only observed at carcasses unoccupied by red foxes, showing greater avoidance when alternative preys are available. Supplementary feeding increased Arctic foxes' carrion use, regardless of red fox presence. Contrary to expectations, we did not find strong signs of asymmetric competition for carrion in winter, which suggests that interactions for resources at a short time scale are not necessarily aligned with interactions at the scale of the population. In addition, we found that competition for carcasses depends on the availability of other resources, suggesting that interactions between predators depend on the ecological context.
The effects of dune plant roots on loggerhead turtle (Caretta caretta) nest success
Authors: Redding Olivia T. , Castorani Max C. N. , Lasala Jake 
Published: April 2024

AbstractSand dunes are supported by the extensive root systems of dune plants that anchor the dune and protect it from erosion. While all plants that grow on the dunes support their structure, invasive plants can outcompete the native and non‐native dune plants for resources such as nutrients, sunlight, and space to grow. During the summer, sea turtles lay nests on beaches and near dunes; however, their eggs and hatchlings are at risk of destruction and entrapment by dune plant root penetration. Dune plant roots can penetrate sea turtle nest cavities, thus decreasing hatch success of the eggs and emergence success of the hatchlings. We aimed to determine how plant roots impact threatened loggerhead sea turtle (Caretta caretta) nests on Casey Key, Sarasota County, Florida, USA and to assess the factors affecting plant root invasion. Specifically, we determined the effect of plant roots on loggerhead sea turtle nest success, the extent of the impact of invasive plants over non‐invasive plants on nests, and if the distance from the dune (barrier) affects whether roots will penetrate the nest. From July to August 2022, we excavated 93 nests to determine the extent of root penetration and identify associated plant species. This field campaign was supported by a long‐term dataset (1987–2022) on loggerhead sea turtle nesting across the region. We found that root presence decreased hatch success by 21% and emergence success by 18%, compared to nests that lacked roots within the nest chamber. Nests closer to the dune were more likely to have a higher proportion of root damage and lower hatch and emergence success. This study helps advance understanding of how native and non‐native plants affect sea turtle reproductive success and helps inform coastal management aimed at conserving threatened loggerhead populations.
A new threshold selection method for species distribution models with presence‐only data: Extracting the mutation point of the P/E curve by threshold regression
Authors: Yu Boyang , Dai Wenyu , Li Siqing , Wu Zhaoning , Wang Jiechen 
Published: April 2024

AbstractSelecting thresholds to convert continuous predictions of species distribution models proves critical for many real‐world applications and model assessments. Prevalent threshold selection methods for presence‐only data require unproven pseudo‐absence data or subjective researchers' decisions. This study proposes a new method, Boyce‐Threshold Quantile Regression (BTQR), to determine thresholds objectively without pseudo‐absence data. We summarize that the mutation point is a typical shape feature of the predicted‐to‐expected (P/E) curve after reviewing relevant articles. Analysis based on source‐sink theory suggests that this mutation point may represent a transition in habitat types and serve as an appropriate threshold. Threshold regression is introduced to accurately locate the mutation point. To validate the effectiveness of BTQR, we used four virtual species of varying prevalence and a real species with reliable distribution data. Six different species distribution models were employed to generate continuous suitability predictions. BTQR and nine other traditional methods transformed these continuous outputs into binary results. Comparative experiments show that BTQR has advantages in terms of accuracy, applicability, and consistency over the existing methods.
Changes and driving factors of microbial community composition and functional groups during the decomposition of Pinus massoniana deadwood
Authors: Shi Bingyang , Wang Xiurong , Yang Shuoyuan , Chen Hongmei , Zhao Yang , Shen Junjie , Xie Meixuan , Huang Bufang 
Published: April 2024

AbstractClarifying changes in the microbial community in deadwood at different stages of decomposition is crucial for comprehending the role of deadwood in the biogeochemical processes and the sustainability of forest development. However, there have been no reports on the dynamics of microbial community during the decomposition of Pinus massoniana. We used the “space‐for‐time” substitution to analyze the characteristics of microbial community changes and the key influencing factors in the P. massoniana deadwood during different decomposition stages by 16S and ITS rRNA gene sequencing. The results suggest that the microbial community structure of the early decomposition (decay class I) was significantly different from the other decay classes, while the diversity and richness of the microbial community were the highest in the late decomposition (decay class V). The Linear Discriminant Analysis Effect Size analysis revealed that most bacterial and fungal taxa were significantly enriched in decay classes I and V deadwood. During the initial stages of decomposition, the relative abundance of the bacterial functional group responsible for carbohydrate metabolism was greater than the later stages. As decomposition progressed, the relative abundance of saprophytic fungi gradually decreased, and there was a shift in the comparative abundance of mixed saprophytic‐symbiotic fungi from low to high before eventually decreasing. Total organic carbon, total nitrogen, carbon‐to‐nitrogen ratio, total potassium, total phenol, condensed tannin, lignin, and cellulose were significantly correlated with microbial community structure, with the carbon‐to‐nitrogen ratio having the greatest effect. Our results indicate that the physicochemical properties of deadwood, microbial community structural composition and functional group changes were related to the decay class, among which the carbon‐to‐nitrogen ratio may be an important factor affecting the composition and diversity of microbial communities.
Visuomotor coordination with gaze, head and arm movements during table tennis forehand rallies
Authors: Shinkai Ryosuke , Ando Shintaro , Nonaka Yuki , Kizuka Tomohiro , Ono Seiji 
Published: April 2024

AbstractThe purpose of this study was to clarify the temporal coordination between gaze, head, and arm movements during forehand rallies in table tennis. Collegiate male table tennis players (n = 7) conducted forehand rallies at a constant tempo (100, 120, and 150 bpm) using a metronome. In each tempo condition, participants performed 30 strokes (a total of 90 strokes). Gaze, head, and dominant arm (shoulder, elbow, and wrist) movements were recorded with an eye‐tracking device equipped with a Gyro sensor and a 3‐D motion capture system. The results showed that the effect of head movements relative to gaze movements was significantly higher than that of eye movements in the three tempo conditions. Our results indicate that head movements are closely associated with gaze movements during rallies. Furthermore, cross‐correlation coefficients (CCs) between head and arm movements were more than 0.96 (maximum coefficient: 0.99). In addition, head and arm movements were synchronized during rallies. Finally, CCs between gaze and arm movements were more than 0.74 (maximum coefficient: 0.99), indicating that gaze movements are temporally coordinated with arm movements. Taken together, head movements could play important roles not only in gaze tracking but also in the temporal coordination with arm movements during table tennis forehand rallies.
Landscape evolution and sediment delivery in a High Arctic proglacial lake, Ellesmere Island, Canadian Arctic Archipelago
Authors: Chassiot Léo , Lajeunesse Patrick , Francus Pierre , Normandeau Alexandre , Lapointe François , Massa Charly , De Coninck Arnaud 
Published: April 2024

AbstractGeophysical and morphosedimentary investigations were conducted at Strathcona Lake, a High Arctic proglacial lake and its catchment connected to the Taggart Lake Glacier, northwest corner of the Prince of Wales Icefield in Ellesmere Island (eastern Canadian Arctic Archipelago). The mapping of glaciomarine landforms and units provides, together with updated radiocarbon information, a framework for catchment evolution and sediment delivery to the lake during deglaciation and glacio‐isostatically induced relative sea level fall. A staircase of deltas with descending altitudes provide evidence for a spatially diachronous timing of ice retreat from the catchments around Strathcona Lake. Swath bathymetric mapping coupled with acoustic sediment stratigraphy show draped infills with a transition from marine to rhythmically bedded lacustrine sediments produced by hyperpycnal flows. Multiproxy investigations on a set of sediment cores highlight proglacial varves interrupted by rhythmites resulting from the erosion of fluvially incised glaciomarine sediments stored in the catchment. Pluricentimetric proglacial varves formed during the last century in response to periods of intense glacial melt, notably since the 21st century. The sedimentary record suggests the varved sediments from Strathcona Lake can be used to reconstruct the melting history of the Prince of Wales Icefield. This work provides a geomorphological, sedimentological, and geochemical framework that should guide future varve‐based reconstructions of glacial and climatic variability in Ellesmere Island.
Spatial variability of soil physicochemical properties under different land uses impacted by erosion on karst hillslopes in Southwest China
Authors: Chen Lei , Zhang Keli , Li Yetong 
Published: April 2024

AbstractKarst hillslopes are generally characterized by different land uses. Land use and slope position impact soil erosion seriously, which in turn impacts the process of soil development and the patterns of soil properties. However, the impact of land use on soil physicochemical properties and the spatial variations and correlations between them are not fully understood on karst hillslopes. Therefore, nine sites had similar soil types, slope gradients, elevations, slope aspects and previous tillage practices were selected to conduct further research. This study was conducted to quantify the spatial distribution, variability and correlation of soil physical and chemical properties and stoichiometries as impacted by different land uses on a karst hillslope in Southwest China. Soil physical properties were significantly affected by slope position and soil depth. The soil bulk density and clay content increased with soil depth, while the opposite was true for the sand content. For the three land uses, the soil bulk density varied the most at the lower slope position, while clay and sand particles varied the most at the middle slope position. The mean spatial coefficient of variation (CV) of soil physical properties was ranked as sand (11.08%) > clay (7.77%) > bulk density (6.85%) > silt (3.81%). The mean spatial CV of soil chemical properties was ranked as available K (44.49%) > total P (16.77%) > total C (16.31%) > total N (13.09%) > available P (8.45%) > total K (7.51%). Overall, soil physicochemical properties exhibited significant spatial differences with slope location and land use on karst hillslopes. Soil chemical properties had greater spatial variation than physical properties, moreover, there were significant correlations between them. The results not only contribute to a deeper understanding of the impact of land use on the erosion process and mechanism on karst hillslopes but also provide a scientific understanding of the sustainable restoration of karst ecosystems.
Association of socioeconomic status and poststroke cognitive function: A systematic review and meta‐analysis
Authors: Tian Jingyuan , Wang Qiuyi , Guo Shuang , Zhao Xiaoqing 
Published: April 2024

AbstractBackgroundStroke survivors are at high risk of coping with cognitive problems after stroke. In recent decades, the relationship between socioeconomic status (SES) and health‐related outcomes has been a topic of considerable interest. Learning more about the potential impact of SES on poststroke cognitive dysfunction is of great importance.ObjectiveThe purpose of this systematic review and meta‐analysis was to summarize the association between SES and poststroke cognitive function by quantifying the effect sizes of the existing studies.MethodWe searched studies from PubMed, Ovid, Embase, Cochrane, Scopus, and PsychINFO up to January 30th 2024 and the references of relevant reviews. Studies reporting the risk of poststroke cognitive dysfunction as assessed by categorized SES indicators were included. The Newcastle‐Ottawa scale and the Agency for Healthcare Research and Quality were used to evaluate the study quality. Meta‐analyses using fixed‐effect models or random‐effect models based on study heterogeneity were performed to estimate the influence of SES on cognitive function after stroke, followed by subgroup analyses stratified by study characteristics.ResultsThirty‐four studies were eligible for this systematic review and meta‐analysis. Of which, 19 studies reported poststroke cognitive impairment (PSCI) as the outcome, 13 reported poststroke dementia (PSD), one reported both PSCI and PSD, and one reported vascular cognitive impairment no dementia. The findings showed that individuals with lower SES levels had a higher risk of combined poststroke cognitive dysfunction (odds ratio (OR) = 1.91, 95% confidence interval (CI) = 1.59–2.29), PSCI (OR = 2.09, 95% CI = 1.57–2.78), and PSD (OR = 1.95, 95% CI = 1.48–2.57). Subgroup analyses stratified by SES indicators demonstrated the protective effects of education and occupation against the diagnoses of combined poststroke cognitive dysfunction, PSCI, and PSD.ConclusionsStroke survivors belonging to a low SES are at high risk of poststroke cognitive dysfunction. Our findings add evidence for public health strategies to reduce the risk of poststroke cognitive dysfunction by reducing SES inequalities.
Comparison between natural rubber knee support and sponge knee support on the protection of knee joint: A crossover randomized controlled study among patients with bleeding disorders
Authors: Maneekhiew Supicha , Kovitwanawong Nalinee , Raweekul Sakrawee , Kijkunasathian Chusak , Panuwannakorn Monratta , Uampornvanich Parsiri , Chuansumrit Ampaiwan , Wongwerawattanakoon Pakawan , Sirachainan Nongnuch 
Published: April 2024

AbstractBackground and AimsKnee support, frequently made from sponge, is used to reduce injury. Sponge has less elasticity and durability compared with natural rubber. To our knowledge, there was no study that demonstrated the effectiveness of natural rubber and sponge in prevention of injury in children with bleeding disorders. The study aimed to demonstrate the effectiveness and satisfaction of natural rubber knee support compared with sponge knee support among children with bleeding disorders.MethodsThe study consisted of three phases: (I) measuring reduced compression force, (II) producing size‐appropriate knee support prototypes, and (III) conducting a randomized crossover trial, including 8 weeks wearing natural rubber knee support and sponge knee support with a 4‐week wash‐out period. The number of knee bleeds and user satisfaction were recorded.ResultsA better compression force reduction in natural rubber (60%) than sponge (12%) was demonstrated. Knee support comprised a body part, made from natural‐stretchable cotton and a protection part, made from either natural rubber or sponge. They were produced in four sizes: S, M, L, and XL and appropriately applied to 42 patients (21 hemophilia, 21 platelet disorders) with a mean (SD) age of 7.0 (2.9) years. The results from randomization showed no significant difference in the number of knee bleeds between the two knee support groups (10 vs. 7, p = 0.37). In terms of satisfaction score, the natural rubber knee supports were more durable (45.2% vs. 23.8%, p = 0.04) and easier to use (28.5% vs. 14.3%, p = 0.03). In addition, a higher percentage of parents chose natural rubber knee support when compared with sponge knee supports (71.0% vs. 29.0%, p = 0.006).ConclusionNatural rubber knee support showed comparable effectiveness in the prevention of knee bleeding but was superior to sponge knee support in compression force reduction and satisfaction.