bluuebunny/crossref_metadata_2025_split huggingface dataset:
Genome-wide identification, phylogenetic classification of histone acetyltransferase genes, and their expression analysis in sugar beet (Beta vulgaris L.) under salt stress
Authors: Yolcu Seher , Skorupa Monika , Uras Mehmet Emin , Mazur Justyna , Ozyiğit Ibrahim Ilker 
Published: March 2024

Abstract
Main conclusion
This study identified seven histone acetyltransferase-encoding genes (HATs) from Beta vulgaris L. (sugar beet) genome through bioinformatics tools and analyzed their expression profiles under salt stress. Sugar beet HATs are phylogenetically divided into four families: GNAT, MYST, CBP, and TAFII250. The BvHAT genes were differentially transcribed in leaves, stems, and roots of B. vulgaris salt-resistant (Casino) and -sensitive (Bravo) cultivars under salt stress.

Abstract
Histone acetylation is regulated by histone acetyltransferases (HATs), which catalyze ɛ-amino bond formation between lysine residues and acetyl groups with a cofactor, acetyl-CoA. Even though the HATs are known to participate in stress response and development in model plants, little is known about the functions of HATs in crops. In sugar beet (Beta vulgaris L.), they have not yet been identified and characterized. Here, an in silico analysis of the HAT gene family in sugar beet was performed, and their expression patterns in leaves, stems, and roots of B. vulgaris were analyzed under salt stress. Salt-resistant (Casino) and -sensitive (Bravo) beet cultivars were used for gene expression assays. Seven HATs were identified from sugar beet genome, and named BvHAG1, BvHAG2, BvHAG3, BvHAG4, BvHAC1, BvHAC2, and BvHAF1. The HAT proteins were divided into 4 groups including MYST, GNAT (GCN5, HAT1, ELP3), CBP and TAFII250. Analysis of cis-acting elements indicated that the BvHAT genes might be involved in hormonal regulation, light response, plant development, and abiotic stress response. The BvHAT genes were differentially expressed in leaves, stems, and roots under control and 300 mM NaCl. In roots of B. vulgaris cv. Bravo, the BvHAG1, BvHAG2, BvHAG4, BvHAF1, and BvHAC1 genes were dramatically expressed after 7 and 14 days of salt stress. Interestingly, the BvHAC2 gene was not expressed under both control and stress conditions. However, the expression of BvHAG2, BvHAG3, BvHAG4, BvHAC1, BvHAC2 genes showed a significant increase in response to salt stress in the roots of cv. Casino. This study provides new insights into the potential roles of histone acetyltransferases in sugar beet.
The Moraxella catarrhalis AdhC–FghA system is important for formaldehyde detoxification and protection against pulmonary clearance
Authors: Othman Dina , Elhosseiny Noha M. , Eltayeb Wafaa N. , Attia Ahmed S. 
Published: March 2024

AbstractMultidrug-resistant clinical isolates of Moraxella catarrhalis have emerged, increasing the demand for the identification of new treatment and prevention strategies. A thorough understanding of how M. catarrhalis can establish an infection and respond to different stressors encountered in the host is crucial for new drug-target identification. Formaldehyde is a highly cytotoxic compound that can be produced endogenously as a by-product of metabolism and exogenously from environmental sources. Pathways responsible for formaldehyde detoxification are thus essential and are found in all domains of life. The current work investigated the role of the system consisting of the S-hydroxymethyl alcohol dehydrogenase (AdhC), a Zn-dependent class III alcohol dehydrogenase, and the S-formyl glutathione hydrolase (FghA) in the formaldehyde detoxification process in M. catarrhalis. Bioinformatics showed that the components of the system are conserved across the species and are highly similar to those of Streptococcus pneumoniae, which share the same biological niche. Isogenic mutants were constructed to study the function of the system in M. catarrhalis. A single fghA knockout mutant did not confer sensitivity to formaldehyde, while the adhC–fghA double mutant is formaldehyde-sensitive. In addition, both mutants were significantly cleared in a murine pulmonary model of infection as compared to the wild type, demonstrating the system’s importance for this pathogen’s virulence. The respective phenotypes were reversed upon the genetic complementation of the mutants. To date, this is the first study investigating the role of the AdhC–FghA system in formaldehyde detoxification and pathogenesis of M. catarrhalis.
Kann Robotisierung den Untertage-Strecken-Sprengvortrieb wesentlich beschleunigen?
Authors: Sifferlinger Nikolaus August , Berner Michael , Fimbinger Eric 
Published: March 2024

ZusammenfassungIm konventionellen Sprengvortrieb in der Streckenauffahrung im Untertagebergbau begrenzt die Notwendigkeit zum Auswettern der Sprenggase die Anzahl der Vortriebszyklen pro Tag.Wenn es gelingt, den gesamten Vorgang mittels Roboter und Teleoperation auszuführen, kann dies geändert werden. Roboter benötigen keine Atemluft und können auch in Sprengschwaden ihre Arbeit verrichten. Die Sprengschwaden müssen dafür durch ein entsprechendes mobiles Wetterschottsystem bis zur nächsten Auswetterungsmöglichkeit in der Vortriebsstrecke gehalten werden. Das Wetterschottsystem muss dem Gasdruck der Sprengungen wiederstehen können.Ein entsprechender mobiler Zwischenspeicher nimmt das gelöste Vortriebsmaterial auf und wird während der Auswetterungsphase entleert. Wenn der Zwischenspeicher das Material von zwei Abschlägen aufnehmen kann, wären bis zu drei Abschlägen zwischen den Auswetterungsphasen möglich, im konventionellen Sprengvortrieb bisher nur ein Abschlag.Eine Verdoppelung der Vortriebsgeschwindigkeit ist also erreichbar.Im Detail ist noch einiges zu lösen, aber die Voraussetzungen für Robotisierung und Teleoperation sind bereits vorhanden.
A reinforcement learning (RL)-based hybrid method for ground penetrating radar (GPR)-driven buried object detection
Authors: Alpdemir Mahmut Nedim , Sezgin Mehmet 
Published: March 2024

AbstractGround penetrating radar (GPR) systems are effective sensors for discovering various types of objects buried underground, such as military mines, metal objects, and pieces of underground infrastructures. A GPR system can be manually operated by a human or can be an integral part of a host platform. The host platform may be semi- or fully autonomous and may operate in different environments such as land vehicles or more recently air-borne drones. One challenge for the fully or semi-autonomous host platforms in particular is to find an efficient search procedure that would reduce the operation time and optimize resource utilization. Most of the current approaches are based on pre-defined search patterns which, for large and sparse areas, could mean unnecessary waste of time and resources. In this paper, we introduce a method that combines a coarse and therefore relatively low cost initial search pattern with a Reinforcement Learning (RL) driven efficient navigation path for eventual target detection, by exploiting the signal processing pipeline of the onboard GPR. We illustrate the applicability of the method using a well-known, high fidelity GPR simulation environment and a novel RL framework. Our results suggest that combination of a coarse navigation scheme and an RL-based training procedure based on GPR scan returns can lead to a more efficient target discovery procedure for host platforms.
Children age group detection based on human–computer interaction and time series analysis
Authors: Ruiz-Garcia Juan Carlos , Hojas Carlos , Tolosana Ruben , Vera-Rodriguez Ruben , Morales Aythami , Fierrez Julian , Ortega-Garcia Javier , Herreros-Rodriguez Jaime 
Published: March 2024

AbstractThis article proposes a novel children–computer interaction (CCI) approach for the task of age group detection. This approach focuses on the automatic analysis of the time series generated from the interaction of the children with mobile devices. In particular, we extract a set of 25 time series related to spatial, pressure, and kinematic information of the children interaction while colouring a tree through a pen stylus tablet, a specific test from the large-scale public ChildCIdb database. A complete analysis of the proposed approach is carried out using different time series selection techniques to choose the most discriminative ones for the age group detection task: (i) a statistical analysis and (ii) an automatic algorithm called sequential forward search (SFS). In addition, different classification algorithms such as dynamic time warping barycenter averaging (DBA) and hidden Markov models (HMM) are studied. Accuracy results over 85% are achieved, outperforming previous approaches in the literature and in more challenging age group conditions. Finally, the approach presented in this study can benefit many children-related applications, for example, towards an age-appropriate environment with the technology.
Maze runners: monkeys show restricted Arabic numeral summation during computerized two-arm maze performance
Authors: Haseltine Elizabeth L. , Beran Michael J. 
Published: March 2024

Abstract
Mazes have been used in many forms to provide compelling results showcasing nonhuman animals’ capacities for spatial navigation, planning, and numerical competence. The current study presented computerized two-arm mazes to four rhesus macaques. Using these mazes, we assessed whether the monkeys could maximize rewards by overcoming mild delays in gratification and sum the values of Arabic numerals. Across four test phases, monkeys used a joystick controller to choose one of two maze arms on the screen. Each maze arm contained zero, one or two Arabic numerals, and any numerals in the chosen maze arm provided the monkeys with rewards equivalent to the value of those numerals. When deciding which arm to enter, monkeys had to consider distance to numerals and numeral value. In some tests, gaining the maximum reward required summing the value of two numerals within a given arm. All four monkeys successfully maximized reward when comparing single numerals and when comparing arms that each contained two numerals. However, some biases occurred that were suboptimal: the largest single numeral and the delay of reward (by placing numerals farther into an arm from the start location) sometimes interfered with the monkeys’ abilities to optimize. These results indicate that monkeys experience difficulties with inhibition toward single, high valence stimuli in tasks where those stimuli must be considered in relation to overall value when represented by symbolic stimuli such as numerals.
Matroid-based TSP rounding for half-integral solutions
Authors: Gupta Anupam , Lee Euiwoong , Li Jason , Mucha Marcin , Newman Heather , Sarkar Sherry 
Published: March 2024

AbstractWe show how to round any half-integral solution to the subtour-elimination relaxation for the TSP, while losing a less-than$$-$$- 1.5 factor. Such a rounding algorithm was recently given by Karlin, Klein, and Oveis Gharan based on sampling from max-entropy distributions. We build on an approach of Haddadan and Newman to show how sampling from the matroid intersection polytope, combined with a novel use of max-entropy sampling, can give better guarantees.
Investigation of the effect of graphene oxide nanoparticles on the structural and dielectric parameters in zinc oxide semiconductors
Authors: Horlu Merve , Macit Cevher Kursat , Aksakal Bunyamin , Tanyeri Burak , Biryan Fatih 
Published: March 2024

AbstractIn this study, pure and 1%, 3% and 5% doped graphene oxide (GO) reinforced zinc oxide (ZnO) nanoparticles were synthesized by sol-gel method. The aim was to improve the electrical and dielectric properties of ZnO semiconductor metal oxide used in many electronic, optoelectronic and electrochemical technologies. FE-SEM, X-ray diffraction (XRD), Raman spectroscopy, energy dispersive spectroscopy and Fourier transform infrared spectroscopy (FT-IR), were used to show the structural and morphological properties of the synthesized ZnO and GO doped ZnO nanoparticles. Impedance analysis was used to study the dielectric properties of the produced nanoparticles. XRD analysis revealed typical peaks of nGO and ZnO nanoparticles. Through the FE-SEM and XRD analysis, it was shown that the ZnO and GO nanopowders were successfully synthesized. The results revealed that ZnO-GO nanoparticles, having good dielectric constant with loss and AC conductivity values, such materials can be a good candidate for solar cells and photovoltaic devices.
Graphical Abstract
Insights into the localisation of outlets: The franchising chains
Authors: Caro-Vela María D. , Ramírez-Hurtado José M. , Calderón-Monge Esther 
Published: March 2024

AbstractThe geographical location of an establishment is a strategic decision of major importance for companies. In the case of franchising, the peculiarities of the system render this decision of vital importance. The objectives of this work are threefold: a) to identify hotspots of franchise establishments; b) to perform an analysis of the distance between establishments; and c) to specify a weighted geographical regression model to estimate the influence of income, population density, and percentage of commercial area of the municipalities on the number of establishments of the franchises located in the chosen municipalities. To this end, 1,508 establishments belonging to seven franchising chains operating in Spain have been selected. The results show that there is an agglomeration of establishments in various geographical areas. Geographically weighted regression also confirms that the variables analysed constitute good predictors of the number of establishments in each municipality.
A minimal and non-alternative realisation of the Cayley plane
Authors: Corradetti Daniele , Marrani Alessio , Zucconi Francesco 
Published: March 2024

AbstractThe compact 16-dimensional Moufang plane, also known as the Cayley plane, has traditionally been defined through the lens of octonionic geometry. In this study, we present a novel approach, demonstrating that the Cayley plane can be defined in an equally clean, straightforward and more economic way using two different division and composition algebras: the paraoctonions and the Okubo algebra. The result is quite surprising since paraoctonions and Okubo algebra possess a weaker algebraic structure than the octonions, since they are non-alternative and do not satisfy the Moufang identities. Intriguingly, the real Okubo algebra has $$\text {SU}\left( 3\right) $$

SU

3

as automorphism group, which is a classical Lie group, while octonions and paraoctonions have an exceptional Lie group of type $$\text {G}_{2}$$

G
2

. This is remarkable, given that the projective plane defined over the real Okubo algebra is nevertheless isomorphic and isometric to the octonionic projective plane which is at the very heart of the geometric realisations of all types of exceptional Lie groups. Despite its historical ties with octonionic geometry, our research underscores the real Okubo algebra as the weakest algebraic structure allowing the definition of the compact 16-dimensional Moufang plane.
Psychosocial correlates of physical activity in cancer survivors: a systematic review and meta-analysis
Authors: Rodrigues Bruno , Encantado Jorge , Franco Sofia , Silva Marlene N. , Carraça Eliana V. 
Published: March 2024

Abstract
Background
Physical activity (PA) is a non-pharmacological approach to optimize health benefits in cancer survivors and is recommended as part of care. However, most cancer survivors fail to meet PA recommendations. The current systematic review and meta-analysis aimed to identify psychosocial correlates of free-living PA in cancer survivors.

Methods
Three electronic databases were searched (PubMed, PsycINFO, and SportDiscus). Meta-analyses were conducted for psychosocial correlates tested ≥ 3 times.

Results
Sixty-four articles were included. Eighty-eight different free-living PA correlates were identified. Meta-analyses (n = 32 studies) tested 23 PA correlates, of which 16 were significant (p < 0.05). Larger effect sizes (0.30 < ES > 0.45) were found for exercise self-efficacy, perceived behavioral control, intention, lower perceived barriers for exercise, enjoyment, perceived PA benefits, and attitudes. Small-to-moderate effects (0.18 < ES < 0.22) were found for subjective norms, physical functioning, quality of life, depression, and mental health. These findings were generally in line with narrative results.

Conclusions
This systematic review highlights important psychosocial correlates of free-living PA that can be targeted in future PA promotion interventions for cancer survivors. Constructs mainly from SCT and TPB were the most studied and appear to be associated with free-living PA in this population. However, we cannot currently assert which frameworks might be more effective. Further studies of better methodological quality, per correlate and theory, exploring longer-term associations and across different types of cancer, are needed.

Implications for Cancer Survivors
Having higher exercise self-efficacy, perceived behavioral control, intention, enjoyment and perceived PA benefits, more positive attitudes towards PA, and lower perceived barriers for exercise, can help increase PA in cancer survivors.
The Pathology of the Brain Eating Amoeba Naegleria fowleri
Authors: Borkens Yannick 
Published: March 2024

AbstractThe genus Naegleria is a taxonomic subfamily consisting of 47 free-living amoebae. The genus can be found in warm aqueous or soil habitats worldwide. The species Naegleria fowleri is probably the best-known species of this genus. As a facultative parasite, the protist is not dependent on hosts to complete its life cycle. However, it can infect humans by entering the nose during water contact, such as swimming, and travel along the olfactory nerve to the brain. There it causes a purulent meningitis (primary amoebic meningoencephalitis or PAME). Symptoms are severe and death usually occurs within the first week. PAME is a frightening infectious disease for which there is neither a proven cure nor a vaccine. In order to contain the disease and give patients any chance to survival, action must be taken quickly. A rapid diagnosis is therefore crucial. PAME is diagnosed by the detection of amoebae in the liquor and later in the cerebrospinal fluid. For this purpose, CSF samples are cultured and stained and finally examined microscopically. Molecular techniques such as PCR or ELISA support the microscopic analysis and secure the diagnosis.
Feeling at Home? A Dynamic Analysis of the Impact of Discrimination, Refugee-Specific, and Participation Characteristics on Recently Arrived Refugees’ Belonging
Authors: Damen Roxy , Dagevos Jaco , Huijnk Willem 
Published: March 2024

AbstractBelonging has regularly been related to discrimination, most studies originally focusing on the contrasting effect of education (and later also employment, language proficiency and social contacts) in explaining belonging through discrimination (e.g. the integration paradox). Yet, few studies focus on ‘feeling at home’ as indicator of belonging among recently arrived refugees nor do they investigate dynamics or include refugee-specific (reception period and mental health) characteristics as determinants. Employing longitudinal survey data on 2484 recently arrived Syrian refugees in the Netherlands to explain their ‘feeling at home’ during the initial period after arrival, results showed the positive impact of changes in mental health, being active during reception and changes in social contacts on changes in Syrians’ feeling at home in the Netherlands. Like in previous studies, higher education was negatively related to Syrians’ feeling at home. Indicating indirect effect for the refugee-specific characteristics we found that those with a better mental health generally perceived discrimination less, resulting in feeling at home in the Netherlands more strongly. Also, among this relatively new group of refugees, perceived discrimination directly and indirectly explains the dynamics in feeling at home. As such, policies targeted at newcomers’ integration can ultimately be effective if being allowed to belong by receiving society members is an integral part of this.
Optical solitons for the dispersive concatenation model with power law of self-phase modulation: undetermined coefficients
Authors: Vega-Guzmán José , Biswas Anjan , Yıldırım Yakup , Alshomrani Ali Saleh 
Published: March 2024

AbstractThis paper recovers 1-soliton solutions to the dispersive concatenation model that comes with power law of self-phase modulation. The method of undetermined coefficients has made this retrieval possible. The parameter constraints are listed for the existence of the solitons. While a full spectrum of solitons is enumerated and exhibited, it is proved that dark 1-solitons exist only for Kerr law of nonlinear refractive index change.
Lithiated Nafion membrane as a single-ion conducting polymer electrolyte in lithium batteries
Authors: Mazzapioda Lucia , Piccolo Francesco , Del Giudice Alessandra , Silvestri Laura , Navarra Maria Assunta 
Published: March 2024

AbstractSingle lithium-ion conducting polymer electrolytes are promising candidates for next generation safer lithium batteries. In this work, Li+-conducting Nafion membranes have been synthesized by using a novel single-step procedure. The Li-Nafion membranes were characterized by means of small-wide angle X-ray scattering, infrared spectroscopy and thermal analysis, for validating the proposed lithiation method. The obtained membranes were swollen in different organic aprotic solvent mixtures and characterized in terms of ionic conductivity, electrochemical stability window, lithium stripping-deposition ability and their interface properties versus lithium metal. The membrane swollen in ethylene carbonate:propylene carbonate (EC:PC, 1:1 w/w) displays good temperature-activated ionic conductivities (σ ≈ 5.5 × 10–4 S cm−1 at 60 °C) and a more stable Li-electrolyte interface with respect to the other samples. This Li-Nafion membrane was tested in a lithium-metal cell adopting LiFePO4 as cathode material. A specific capacity of 140 mAhg−1, after 50 cycles, was achieved at 30 °C, demonstrating the feasibility of the proposed Li-Nafion membrane.
Trade Secrets and the Data Act
Authors: Mylly Ulla-Maija 
Published: March 2024

AbstractAutomated systems collect vast amounts of data, which could be utilized across various business sectors. The EU has recognized their potential for the data economy. To exploit such potential, there is a need to provide access to data. For example, the objective of the EU’s Data Act is to provide new possibilities for accessing and reusing information. Some information exchanged may be subject to trade secret protection. However, specific characteristics of trade secret protection create difficulties for information sharing. In essence, trade secret protection requires that information should be kept secret, or at least relatively secret. This requirement contributes to the reluctance of trade secret holders to share their information. They would rather lock it down. That is because, if the information becomes generally known in industry circles, it will lose its trade secret status along with any related competitive advantage. At the same time, trade secret protection leaves considerable room for competition, which arguably makes it suited to the data economy. A trade secret is not an exclusive right, which means that competitors may independently create similar information. Access to information through reverse engineering is also allowed. All these specific characteristics make trade secret protection an uncertain means of protection. This article will elaborate on how the uncertainties and specifics related to trade secret protection create a conflict between demand for access to information and the protection of trade secrets. It will analyze how the provisions of the Data Act aim to accommodate the protection of trade secrets while simultaneously mandating access.