bluuebunny/crossref_metadata_2025_split huggingface dataset:
Posttraumatic stress symptoms during treatment in parents of children diagnosed with cancer
Authors: Sopori Varsha Mishra , Lingayat Aditi Maruti , Irfan Aziz Farookh 
Published: February 2024

The study aimed to study the presence of PTSS in parents of children with cancer currently on treatment and the association of PTSS in parents with cancer during treatment with length of time since diagnosis and treatment intensity. The study was conducted on 360 parents at a Tertiary Care Government Medical College and Cancer Hospital. The participants were subjected to the questionnaire PTSD Checklist Civilian Version (PCL-C) scale, to assess PTSS and Oncologists rated the intensity of each child's treatment. The most common age group in the parents was of young adults 25-34years [255(71%)]. Majority of parents were male 288(80%). It was found that PTSD was present in majority of parents [235(65.27%]. On statistical analysis, no significant relationship was found between PTSS in mothers and fathers (p=0.1664). There was no significant relationship between PTSS and the length of time since diagnosis in both mothers (P=0.85) and fathers (P=0.32). No significant relationship was found between the intensity of treatment and PTSD in mothers on statistical analysis (p&#60;0.3). While PTSD in fathers showed significant correlation with the intensity of treatment of the child (p&#60;0.05). There are very few studies regarding examining emotional distress of parents of children with malignancies in our country. Hence, studying PTSS in parents of children with cancer seems to be significant and more research needs to be done in this area.
TOPS score (T-temperature, O-Oxygen saturation, P- Perfusion, S- Sugar) on admission in transported neonates to tertiary care hospital
Authors: Roy Anna , Patel Priti , Ladumor Hitesh Mathurbhai , Gajjar Aditya Pravinkumar 
Published: February 2024

In India, 70% of deliveries take place in rural areas and the transport of the preterm babies to a tertiary care centre are referred only after the birth Babies must be transported to a higher level neonatal intensive care unit (NICU) to overcome the negative effects of critical illness such as respiratory distress and asphyxia in newborns. Most of the neonates are transported without any pre-transport stabilization or care during transport, which can have serious clinical implications on the ultimate outcome of babies. To assess the clinical condition and presence of complications among neonates transported to NICU. To predict outcome of transported neonates in terms of morbidity and mortality based on TOPS score. A cross-sectional observational study was conducted among 500 newborns admitted in NICU, at New Civil Hospital, Surat. Out of total, 258(51.3%) and 245(48.7%) patients were respectively males and females in the study. Out of the 503referred neonates 258 (51.3%) were referred for respiratory distress and ventillatory support, 138(27.4%) were referred for LBW / prematurity. The hypothermia was present post transport approximately among 64% neonates. Hypoglycaemia was found in only 18% of transported neonates. 33% of the studies neonates were hypoxic on reaching the referral centre and the remaining maintained spo2 above 90%.The high sensitivity (81%) and high negative predictive value (87.4%) with a specificity of 61.5% and positive predictive value of 59.7% suggest that TOPS score a very strong screening test to predict the outcome of babies admitted.
Cutaneous metastasis in a case of carcinoma floor of mouth- A rare case report
Authors: Grover Romi Kant , Priya Sheenu , Garg Pardeep , Goyal Navik 
Published: February 2024

The incidence of cutaneous metastasis in head and neck cancers is less than 1%. Carcinoma of the oral cavity is one of the most common cancers of the head neck region with frequent metastasis to internal organs, especially the lungs, liver, and bone.We present a case of Carcinoma of floor of mouth with cutaneous metastasis.A 55 year old lady presented to our department with complaints of non-healing ulcer in the oral cavity and ulcerated nodules over neck and chest. On examination, mouth opening tongue mobility was restricted with grade 2 trismus. An ulcer in left gb sulcus, bilateral lymphadenopathy and multiple ulcerated skin nodules on neck and chest wall were noted. CECT Face and Neck showed heterogenously ehancing mass at the floor of mouth involving left buccal mucosa and erosion of mandible, lymph node mets and skin nodules. ECOGPS was 1.She was treated with palliative systemic chemotherapy and thereafter Palliative radiation. Now she is having stable disease and is on metronomic chemotherapy with regular follow up.Our case has highlighted that cutaneous metastasis can be seen in the cancers of floor of mouth. Palliative chemotherapy and radiotherapy can significantly increase Progression free survival and hence the Quality of life of patients with such presentation.
Upaya Guru Bimbingan dan Konseling dalam Mengatasi Cyberbullying
Authors: Yusniarti Nela 
Published: February 2024

Penelitian ini bertujuan untuk mengetahui upaya guru bimbingan dan konseling dalam mengatasi cyberbullying. Jenis penelitian ini termasuk dalam metode penelitian kualitatif yang didasarkan pada studi literatur atau penelitian kepustakaan. Metode penelitian studi literatur melibatkan pengumpulan referensi yang sesuai dengan tujuan penelitian secara ilmiah, penggunaan kepustakaan sebagai teknik pengumpulan data, serta integrasi dan penyajian data. Hasil penelitian menunjukkan terdapat beberapa langkah strategis yang bisa diambil untuk mencegah terjadinya tindakan cyberbullying di kalangan siswa, termasuk memperkuat peran agen perubahan di lingkungan sekolah, melibatkan teman sebaya dalam mendukung teman-teman dengan kebutuhan khusus, mengadakan kampanye anti perundungan melalui penggunaan poster, dan mempromosikan kerja sama antara orangtua, sekolah, dan rekan-rekan sebaya dalam upaya meningkatkan literasi digital dan mendukung gerakan anti cyberbullying. Guru BK juga memiliki peran penting dengan memberikan layanan informasi, konseling, dan konferensi kasus. Selain itu, pembentukan tim cyber safe dapat membantu melindungi peserta didik dari cyberbullying. Upaya pencegahan cyberbullying melibatkan penguatan etika bermedia sosial, peran teman sebaya yang positif, kampanye anti-perundungan, dan kerjasama dengan orangtua dan teman sebaya. Pelatihan bagi guru juga diperlukan untuk meningkatkan pemahaman mereka tentang isu-isu terkait cyberbullying. Mereka berperan penting dalam membantu siswa menghadapi dampak cyberbullying, yang merupakan tindakan intimidasi di dunia maya dengan dampak serius.
Kecemasan Karir: Konsep Diri dan Dukungan Sosial pada Mahasiswa
Authors: Fadel* Alda Fahira , Kinayung Dian 
Published: February 2024

Penelitian ini bertujuan untuk mengetahui hubungan antara konsep diri dan dukungan sosial dengan kecemasan karir. Subjek penelitian ini adalah mahasiswa fakultas psikologi angkatan 2019 Universitas Ahmad Dahlan Yogyakarta. Jumlah sampel yang peneliti teliti adalah 166 responden, teknik sampling menggunakan cluster random sampling Metode penelitian yang digunakan adalah pendekatan kuantitatif dengan menggunakan alat ukur berupa skala kecemasan karir, skala konsep diri, dan skala dukungan sosial. Pendekatan regresi linier berganda digunakan untuk menganalisis data. Hasil analisis menunjukkan temuan sebagai berikut: 1) Adanya hubungan yang sangat signifikan antara konsep diri dan dukungan sosial dengan kecemasan karir (R = 0,597; p = 0,000). 2) Terdapat hubungan negatif yang sangat signifikan antara konsep diri dengan kecemasan karir (r = -0,568; p = 0,000). 3) Tidak terdapat hubungan antara dukungan sosial dengan kecemasan karir (r = 0,140; p = 0,072). Berdasarkan hasil tersebut dapat disimpulkan bahwa konsep diri dan dukungan sosial secara bersama-sama memiliki korelasi dengan kecemasan karir, namun jika dianalisis secara terpisah konsep diri memiliki korelasi dengan kecemasan karir sedangkan dukungan sosial tidak menunjukkan korelasi tersebut.
PMO/ZnO nanocomposites as nanocarriers for gemcitabine release
Authors: Hajesmaeli Azadeh , Bahrami Zohreh 
Published: February 2024

Abstract
In this study, periodic mesoporous organosilica (PMO)/ZnO nanocomposites were synthesized and investigated as a delivery system for the anticancer drug (gemcitabine). Rice bran extract was used for the green synthesis of ZnO nanoparticles. According to the characteristic results, by increasing the amount of ZnO, the size of the spherical particles increased and surface area and pore volume decreased. Between the two nanocomposites, the maximum gemcitabine loading content (53.1%) is related to the sample with the lowest concentration of ZnO nanoparticles. For all samples, the gemcitabine release at pH=5.6 is greater than pH=7.4. The rate of gemcitabine release was fast in the first 8 hours and decreased over time.
A systematic review of how endocrine disrupting contaminants are sampled in environmental compartments: wildlife impacts are overshadowed by environmental surveillance.
Authors: Simms Angela , Robert Kylie , Spencer Ricky-John , Treby Sarah , Williams-Kelly Kelly , Sexton Candice , Korossy-Horwood Rebecca , Terry Regan , Parker Abigail , Dyke James Van 
Published: February 2024

Abstract
Endocrine disrupting contaminants (EDCs) are frequently monitored in environments because of their biological impacts on wildlife and humans. We conducted a systematic review using Web of Science to identify global research trends in abiotic and biotic EDC environmental sampling. Specifically, we aim to better understand geographic variation in 1) the compartment that EDCs were sampled in the environment; 2) the types of EDC sampled; and 3) the taxa that are sampled. A total of 9,140 papers were found in our search, of which 2,554 were included in our review. The number of studies sampling environmental EDCs varied between continents, with the majority of research occurring in Europe, Asia, and North America. Across all continents, water was the most frequently sampled compartment to determine environmental EDC concentrations, and was sampled in 50–75% of studies across continents. Wildlife were sampled far less often in studies across all continents, and comprised of 30% of studies at most. Pharmaceuticals were the most-commonly studied chemical group, and fish were the most-commonly sampled taxonomic group. Although far fewer studies sampled for EDC’s in wildlife compared with abiotic compartments (i.e. water). These studies provide valuable information on the potential consequences of environmental EDC exposure and link environmental surveillance of EDCs with lab-measured organism-level effects. Studies that sampled only the water matrix for EDCs may be doing so as a proxy despite the large knowledge gaps on how environmental EDCs affect wildlife at varying concentrations.
Three-stage location-routing programming for heavy-duty railway maintenance machinery maintenance base based on multi-factor combined weights
Authors: Qiu Shi , Yang Bobo , Zaheer Qasim , Wang Weidong , Sun Ying , Liu Xianhua , Xiao Chunzhong , Wang Jin 
Published: February 2024

Abstract

An imperative shift towards a scientific and methodical approach has become increasingly essential when deliberating the placement of maintenance bases for robust railway machinery dedicated to heavy-duty tasks. This article addresses the need for a systematic approach to placing maintenance bases for robust heavy-duty railway machinery. It introduces a meticulously crafted three-stage location-routing paradigm that factors in both qualitative and quantitative determinants. This approach optimizes routing strategies for the machinery while constructing an evaluative framework for base placement. An evaluative index is created by merging relevant qualitative and quantitative elements, using an enhanced game theory methodology combined with the evidential analytic hierarchy process and the entropy weight method to balance subjective and objective considerations. The model’s complexity is handled with an improved genetic algorithm and a hybrid ant colony algorithm, effectively addressing location and routing interactions. Practical implementation and case studies validate the model’s and algorithm’s efficacy, confirming their applicability in real-world scenarios.
Effect of High-Intensity Focused Electromagnetic technology in the treatment of female stress urinary incontinence
Authors: Long Cheng-Yu , Lin Kun-Ling , Chang Chieh-Yu , Yeh Chang-Lin , Feng Chien-Wei , Loo Zi-Xi 
Published: February 2024

Abstract
The study aimed to assess the effect of High-Intensity Focused Electromagnetic (HIFEM) technology in treating female stress urinary incontinence (SUI). Twenty women with SUI were delivered a treatment course with HIFEM technology. Patients attended six therapies scheduled twice a week. Urodynamic exams, pad tests, and validated questionnaires were assessed, including OABSS, UDI-6, IIQ-7, ICI-Q, and vaginal laxity questionnaire. We also evaluated the bladder neck mobility in ultrasound topography pre- and post-treatment at 1- and 6-month follow-up visits. As for the results, HIFEM treatment significantly improved SUI symptoms on pad tests and patients’ self-assessments in the 6-month follow-up. Besides, the data from urinary-related questionnaires all showed a significant reduction. The analysis of the urodynamic study revealed that only maximum urethral closure pressure and urethral closure area significantly increased after the six sessions of HIFEM treatment. The urethral and vaginal topography was examined, and found that HIFEM mainly worked on pelvic floor muscle and enhanced its function and integrity. In conclusion, HIFEM technology is an efficacious therapy for treating SUI.
Cotton Fiber-Based 1D Conductor：A New Type of Flexible Wire for Cryogenic Electrical System
Authors: Li Si-Zhe , Huang Gui-Wen , Li Na , Liu Yu , Qu Cheng-Bing , Li Meng , Cao Rui-Xiao , Wang Yang , Xiao Hong-Mei 
Published: February 2024

Abstract
In response to the problem of poor flexibility of common one-dimensional flexible conductors at low temperatures, this paper proposed a one-dimensional flexible conductive composite material with cotton fiber as the substrate and silver-nanowires as the conductive fillers to meet the demands of flexible conductors in low temperature fields such as space exploration, superconductivity, low-temperature biology, etc.Through a creative "bottom-up" fabricating process, by adjusting the amount of filler added and the degree of intertwining between cotton fibers, 1D flexible conductor with good flexibility, conductivity, strength and stability is obtained. After 10,000 times of flexibility tests at liquid nitrogen temperature (77K), the resistance change of the 1D conductor is less than ±0.5%, showing excellent flexibility and stability of the material at low temperature environment. A demonstration was then successfully conducted by connecting the 1D conductor to the circuit as the flexible part of the system in simulated working environment (77K). The system worked well with good stability under repeated bending of the mechanical arm, demonstrating high applying potential of the 1D conductor in the field of low-temperature flexible conductive materials.
Impact of rainfall, atmospheric pressure, and temperature on seismic velocity variations at different depths in Volcán de Colima, Mexico using Noise Interferometry
Authors: Ibarra-Morales Juan , De Plaen Raphael , Márquez-Ramírez Víctor Hugo , Dávila-Madrid Ramón Zúñiga , Vargas-Bracamontes Dulce , Arámbula-Mendoza Raúl 
Published: February 2024

Abstract
Earth’s crust is subject to changes triggered by various processes occurring both over (i.e. weather variations), and under (i.e. magmatic, tectonic) the surface simultaneously. Seismic noise interferometry technique allows us to monitor these physical changes by retrieving the relative seismic velocity changes (dv/v). However, detailed analysis is usually needed to differentiate which processes contribute to the final variation of dv/v to produce an accurate monitoring of the upper crust. In this work, we analyzed the daily dv/v in the volume surrounding Colima Volcano calculated using the single-station cross-component (SC) method on seismic records from 2013-2017. We focused on two frequency bands (0.1-1, 1-2 Hz) to retrieve velocity changes at different depths (4 and 1 km, respectively) and compare their differences. Both dv/v signals showed co-seismic velocity drops and annual variations.
Using wavelet transform coherence, we found that three environmental parameters—rainfall, temperature, and atmospheric pressure—might influence the temporal variation of dv/v.
To correct the dv/v time series, we fitted two models based on: 1) rainfall-induced pore pressure coupled with barometric variations and 2) thermoelastic strains.
By comparing the calculated and corrected dv/v signals, we observed that atmospheric pressure-induced velocity variations are neglectable. Rainfall-induced pore pressure can cause velocity drops, especially on the 1-2 Hz signal. Thermoelastic strains seem to cause variations up to +/-0.5% on both band frequencies. These observations support previous hypotheses about rain causing dv/v changes in the top hundreds of meters of the crust, while thermoelastic strains can propagate and induce dv/v variations at greater depths.
Genome-wide characterisation of HD-Zip transcription factors and functional analysis of PbHB24 during stone cell formation in Chinese white pear (Pyrus bretschneideri)
Authors: Wang Qi , Wang Yueyang , Zhang Fanhang , Han Chengyang , Wang Yanling , Ren Mei , Qi Kaijie , Xie Zhihua , Zhang Shaoling , Tao Shutian , Shiratake Katsuhiro 
Published: February 2024

Abstract
Background
The homodomain-leucine zipper (HD-Zip) is a conserved transcription factor unique to plants that regulate multiple developmental processes including lignificaion. Stone cell content is a key determinant negatively affecting pear fruit quality, which causes a grainy texture of fruit flesh, because of the lignified cell walls.
Results
In this study, a comprehensive bioinformatics analysis of PbHB gene family in the pear genome was performed. Genome-wide identification of the PbHB gene family revealed 67 genes encoding PbHB proteins, which could be divided into four subgroups (I, II, III, and IV). Similar intron/exon structural patterns were observed within the same subgroups, strongly supporting their close evolutionary relationships. The functions of each subgroup of the PbHB family were predicted through comparative analysis with the HB genes in Arabidopsis and other plants. Cis-element analysis indicated that PbHB genes might be involved in plant hormone signalling and external environmental responses, such as light, stress, and temperature. Furthermore, RNA-sequencing data and quantitative real-time PCR (RT-qPCR) verification revealed the regulatory roles of PbHB genes in pear stone cell formation. Further, co-expression network analysis revealed that the eight PbHB genes could be classified into different clusters of co-expression with lignin-related genes. Besides, the biological function of PbHB24 in promoting stone cell formation has been demonstrated by overexpression in fruitlets.
Conclusions
This study provided the comprehensive analysis of PbHBs and highlighted the importance of PbHB24 during stone cell development in pear fruits.
Investigating published research towards a fossil-energy-free agriculture transformation
Authors: Balafoutis Athanasios T. , Borzecka Magdalena , Rozakis Stelios , Troullaki Katerina , Vandorou Foteini , Wydra Malgorzata 
Published: February 2024

Abstract
The defossilisation of the agricultural sector is driven by intense worldwide academic research on non-fossil and energy-efficient agriculture, and the acknowledgment of the need for sustainable farming practices. For this purpose, not only technical transformations but also socio-technical system changes towards sustainability need to take place in a co-evolutionary manner. This paper investigates structural and qualitative characteristics of the knowledge produced by research on fossil-energy-free agriculture. We provide evidence on the worldwide research directions, as well as investigate whether academic research and publicly funded research projects foster knowledge creation for the desired transformation. Social network analysis and dictionary-based content analysis are used to relate transformational capacity to project profiles in the European Union to evaluate past funding schemes and to improve the shape of future research programs.
Severe pneumonia caused by Tropheryma whipplei combined with herpes simplex virus type 1 infection in an elderly: a case report of immunocompetent patient
Authors: Chen Jiaxing , Niu Hongbo , Liu Yupeng 
Published: February 2024

Abstract

Background
Whipple's disease is a rare infectious disease with multi system damage caused by Tropheryma whipplei infection. Classic Whipple's disease often is presents with polyarthritis, digestive system symptoms, and weight loss. The atypical symptoms caused by Tropheryma whipplei infection, harsh in vitro culture conditions, and easily is to be complicated with other pathogenic bacteria infection, which have brought great difficulties and challenges to clinical diagnosis. Herpes simplex virus type 1 infection is common in immunocompromised patients or ventilator-associated pneumonia, but herpes simplex virus type 1 pneumonia is very rare in immunocompetent patients. Without timely diagnosis and treatment, the impact on patients is usually fatal.
Case presentation
The patient reported in this paper is an 87-year-old female with normal immune function, who suffered from severe pneumonia caused by Tropheryma whipplei and herpes simplex virus type 1 infection. After the diagnosis was confirmed by metagenomic next-generation sequencing, we started treatment with TMP-SMX and acyclovir, and her symptoms improved rapidly and she was successfully discharged from the hospital.
Conclusions
As far as we know, pneumonia caused by Tropheryma whipplei and herpes simplex virus type 1 is very rare, and early diagnosis and treatment are crucial, because it can improve the prognosis of patients.
Simulation Based Design Tool for Radial Impellers of Centrifugal Pumps
Authors: Hassan Ahmed Farid Saad Ayad , Saleh Sherif , Hashish Anwer 
Published: February 2024

Abstract
Centrifugal water pumps account for more than 20% of energy use all over the world. Even a little increase in centrifugal pump operating efficiency may result in billions of dollars in savings each year and help reduce carbon dioxide emissions. This study creates a design tool that integrates one-dimensional equations and Computational Fluid Dynamics (CFD) simulations to design a centrifugal pump impeller. This examines different combinations of design factors by utilizing both the powerful numerical tools that allow the modeling of numerous scenarios and the large amount of empirical equations and coefficients that represent the significant knowledge accumulated in this field. The design tool runs through a series of equations to select the beginning candidates for the different impeller design variables. After that, a design space is established by generating upper and lower bounds for each design variable. The CFD tool executes numerous scenarios inside the design space in order to find the best candidates with the maximum operating efficiency and meet the design objectives. A low specific speed centrifugal pump with a semi-open impeller is used as a case study. The design tool is successful in designing it, fulfilling the design requirement, and increasing operational efficiency when compared to a simple single-arc comparable impeller.