bluuebunny/crossref_metadata_2025_split huggingface dataset:
A Revit-Midas/Civil conversion approach for bridge superstructures analysis
Authors: Li Jian , Song Haoxin , Zhou Zhenwei , Yang Chao , Wang Liyu , Li Hongtao 
Published: March 2024

Abstract
In this study, a model conversion method that combined Revit with Midas Civil software was proposed to improve the modeling efficiency and accuracy of finite element calculations for a large bridge structure. The secondary development program was established using the Visual Studio 2022 platform, which was used to convert the model information. A model conversion interface was created by extracting, screening, and then sorting the geometric information of the business information model and generating a Midas Civil Text file. This interface served as a link between Revit and Midas Civil, specifically for the bridge superstructure. The feasibility and reliability of the proposed model conversion method was confirmed using a single-box three-cell Box-girder bridge. The results demonstrated that the model conversion method transfered the Revit model information successfully to a Midas Civil structural analysis model, thereby significantly enhancing the efficiency and accuracy of the finite element modeling of a complex bridge superstructure.
Gas turbine aero engine fault detection using Geo-TLSVM and digital twin with multimodal data analysis
Authors: Tadepalli Naga Venkata Rama Subbarao , Koona Ramji 
Published: March 2024

Abstract
DT is the digital representation of physical systems to simulate real situations in a digital version. Here, the DT of the GaT-AE is created for the Fault Detection (FD) process. The GaT is a type of internal combustion engine that uses the air as the working fluid to propel the flight. However, the incorporation of big data analysis in the DT model is challenging in previous works. So, a multimodal GaT-AE fault identification system is proposed. First, the 3D print of the GaT-AE is created. Then, the data is collected from both built-in sensors and DT. Afterward, the multimodal data is pre-processed and balanced by using HT-QNN and QADASYN, respectively. Next, the features are processed by GT-PFS, and finally, the faults are detected by Geo-TLSVM. The analysis proved that the developed model outperformed the other state-of-the-art model with its effective FD rate of 97.24%.
Multifunctional applications of passive solar stills in water treatment: an eco-friendly approach
Authors: Singh Krishn Pratap , Dixit Abhishek , Singh Deepesh 
Published: March 2024

Abstract
Conventional raw water treatment methods are expensive and require a sufficient energy supply for their operations. In remote and rural areas, these conventional methods are feasible due to a poor economy and interrupted power supply. This study provides a sustainable approach to treating raw water using solar energy and phase change material (PCM). Passive solar stills (SS) are sufficient to treat water in the presence of solar radiation, and we can increase the yield and quality of distillate water by using calcium chloride hexahydrate as a phase change material. Moreover, PCM-based solar still is also advanced by adding activated charcoal (AC) for the removal of fluoride from the raw water. The efficiency of the solar still was assessed for the eight parameters: yield (Y), fluoride (F), total dissolved solids (TDS), electrical conductivity (EC), pH, total alkalinity (TA), total hardness (TH), chloride (Cl). Through the number of water quality assessments, it was found that SS with PCM can reduce (%) the TDS (85%–100%), EC (90%–100%), pH (0%–15%), TH (90%–95%), TA (75%–90%), and Cl (80%–100%) and can increase the yield by 10%–15%. SS with PCM and AC also showed good removal of F from raw water. In addition to that, a statistical analysis was also carried out to understand the effect of different climatic factors on the performance of solar stills.
The human subthalamic nucleus transiently inhibits active attentional processes
Authors: Soh Cheol , Hervault Mario , Chalkley Nathan H , Moore Cathleen M , Rohl Andrea , Zhang Qiang , Uc Ergun Y , Greenlee Jeremy D W , Wessel Jan R 
Published: March 2024

Abstract
The subthalamic nucleus (STN) of the basal ganglia is key to the inhibitory control of movement. Consequently, it is a primary target for the neurosurgical treatment of movement disorders like Parkinson’s disease, where modulating the STN via deep brain stimulation (DBS) can release excess inhibition of thalamocortical motor circuits. However, the STN is also anatomically connected to other thalamocortical circuits, including those underlying cognitive processes like attention. Notably, STN-DBS can also affect these processes. This suggests that the STN may also contribute to the inhibition of non-motor activity and that STN-DBS may cause changes to this inhibition. Here we tested this hypothesis in humans.
We used a novel, wireless outpatient method to record intracranial local field potentials (LFP) from STN DBS implants during a visual attention task (Experiment 1, n = 12). These outpatient measurements allowed the simultaneous recording of high-density EEG, which we used to derive the steady state visual evoked potential (SSVEP), a well established neural index of visual attentional engagement. By relating STN activity to this neural marker of attention (instead of overt behaviour), we avoided possible confounds resulting from STN’s motor role. We aimed to test whether the STN contributes to the momentary inhibition of the SSVEP caused by unexpected, distracting sounds. Furthermore, we causally tested this association in a second experiment, where we modulated STN via DBS across two sessions of the task, spaced at least 1 week apart (n = 21, no sample overlap with Experiment 1).
The LFP recordings in Experiment 1 showed that reductions of the SSVEP after distracting sounds were preceded by sound-related γ-frequency (&gt;60 Hz) activity in the STN. Trial-to-trial modelling further showed that this STN activity statistically mediated the sounds’ suppressive effect on the SSVEP. In Experiment 2, modulating STN activity via DBS significantly reduced these sound-related SSVEP reductions. This provides causal evidence for the role of the STN in the surprise-related inhibition of attention.
These findings suggest that the human STN contributes to the inhibition of attention, a non-motor process. This supports a domain-general view of the inhibitory role of the STN. Furthermore, these findings also suggest a potential mechanism underlying some of the known cognitive side effects of STN-DBS treatment, especially on attentional processes. Finally, our newly established outpatient LFP recording technique facilitates the testing of the role of subcortical nuclei in complex cognitive tasks, alongside recordings from the rest of the brain, and in much shorter time than peri-surgical recordings.
Cholinergic changes in Lewy body disease: implications for presentation, progression and subtypes
Authors: Okkels Niels , Grothe Michel J , Taylor John-Paul , Hasselbalch Steen Gregers , Fedorova Tatyana D , Knudsen Karoline , van der Zee Sygrid , van Laar Teus , Bohnen Nicolaas I , Borghammer Per , Horsager Jacob 
Published: March 2024

Abstract
Cholinergic degeneration is significant in Lewy body disease, including Parkinson’s disease, dementia with Lewy bodies, and isolated REM sleep behaviour disorder. Extensive research has demonstrated cholinergic alterations in the CNS of these disorders. More recently, studies have revealed cholinergic denervation in organs that receive parasympathetic denervation. This enables a comprehensive review of cholinergic changes in Lewy body disease, encompassing both central and peripheral regions, various disease stages and diagnostic categories.
Across studies, brain regions affected in Lewy body dementia show equal or greater levels of cholinergic impairment compared to the brain regions affected in Lewy body disease without dementia. This observation suggests a continuum of cholinergic alterations between these disorders. Patients without dementia exhibit relative sparing of limbic regions, whereas occipital and superior temporal regions appear to be affected to a similar extent in patients with and without dementia. This implies that posterior cholinergic cell groups in the basal forebrain are affected in the early stages of Lewy body disorders, while more anterior regions are typically affected later in the disease progression. The topographical changes observed in patients affected by comorbid Alzheimer pathology may reflect a combination of changes seen in pure forms of Lewy body disease and those seen in Alzheimer’s disease. This suggests that Alzheimer co-pathology is important to understand cholinergic degeneration in Lewy body disease. Thalamic cholinergic innervation is more affected in Lewy body patients with dementia compared to those without dementia, and this may contribute to the distinct clinical presentations observed in these groups. In patients with Alzheimer’s disease, the thalamus is variably affected, suggesting a different sequential involvement of cholinergic cell groups in Alzheimer’s disease compared to Lewy body disease. Patients with isolated REM sleep behaviour disorder demonstrate cholinergic denervation in abdominal organs that receive parasympathetic innervation from the dorsal motor nucleus of the vagus, similar to patients who experienced this sleep disorder in their prodrome. This implies that REM sleep behaviour disorder is important for understanding peripheral cholinergic changes in both prodromal and manifest phases of Lewy body disease.
In conclusion, cholinergic changes in Lewy body disease carry implications for understanding phenotypes and the influence of Alzheimer co-pathology, delineating subtypes and pathological spreading routes, and for developing tailored treatments targeting the cholinergic system.
Making amends: emotions and the western response to Russia's invasion of Ukraine
Authors: Floyd Rita , Webber Mark 
Published: March 2024

Abstract
The western response to Russia's full-scale invasion of Ukraine in February 2022 was unprecedented. The states of the European Union, the G7 and NATO have targeted Russia with sanctions and diplomatic isolation, and furnished Ukraine with military assistance sufficient to ensure the Zelensky regime's survival. These efforts have proven insufficient to dislodge Russia from its occupation of Ukrainian territory. Nonetheless, when launched in the aftermath of the invasion, they were seen (and often justified as) as bold, innovative, and steadfast—a necessary response to a grievous act. What explains this response? In this article we argue that the answer lies in the emotions of guilt and shame for past actions and mistakes in the West's dealings with Russia and Ukraine. Informed by a qualitative discourse analysis of key speeches, statements and interviews with leading western policy-makers (past and present), we regard these two emotions—expressed as apologies and the acknowledgment of mistakes—as important drivers of policy. This article contributes to the bourgeoning literature on emotions in world politics. In addition to offering a coherent explanation of the West's unprecedented response our argument has policy implications. While the admission of wrongdoing is laudable, it can lead to actors overcompensating, resulting in further mistakes and policy failures. Fast-tracking Ukraine into the European Union would be one such error.
Understanding Bangladesh's security governance through peacekeeping assemblage: does contribution matter?
Authors: Biswas Niloy Ranjan 
Published: March 2024

Abstract
How do international peacekeeping experiences inform the security governance of contributing states from the global South? This article advances theoretical and policy arguments that international peacekeeping exposure contributes to forming multitudes of effects on domestic security affairs and shaping the contributing countries' security governance. The analysis problematizes the transformation of norms, policies, practices and institutional approaches in shaping the national security outlook of the contributing nations. Considering peacekeeping as a discursive ‘glo-cal’ affair and Bangladesh as a critical case, this study underscores how Bangladesh's contributions to United Nations Peace Support Operations (UNPSOs) inform its security governance. The article adopts a qualitative–interpretive approach to examine the assembling effects of Bangladesh's participation in such endeavours. It highlights the transformation in security institutions, new capacities in knowledge and income-generating sectors, new peacekeeping norms, and partnerships in security cooperation as the cornerstones in the national security outlook. Extending the purview of the existing literature on contributors' roles and impact, this article has offered assemblage as a dynamic conceptual lens to understand new domestic significance for the armed forces as global peace providers. Challenges related to the struggle for democracy, political stability and good governance persist in Bangladesh; nevertheless, the peacekeeping assemblage explains how the country has considered accelerating its global peace endeavours.
Evaluating team-based learning in a foundation training pathway for trainee pharmacists
Authors: Medlinskiene Kristina , Hill Suzanne , Tweddell Simon , Quinn Gemma 
Published: March 2024

Abstract

Background
A new programme incorporating online study days delivered using team-based learning (TBL) for hospital-based trainee pharmacists (TPs) in the North of England was created. To our knowledge, TBL has not previously been used in educational programmes for TPs designed to supplement their workplace learning. The project aimed to investigate the experiences of TPs learning using online TBL by exploring their perceptions on their engagement, learning, and satisfaction with TBL.

Method
Data were collected using online anonymous surveys at the end of four online TBL study days. A bespoke survey consisted of 5-point or 4-point Likert scale and two free text questions. TBL Student Assessment Instrument (SAI), a validated survey, was used to assess TPs’ acceptance of TBL. Survey data was summarized descriptively, and free text comments analysed using thematic analysis.

Results
TPs developed accountability to their team, remained engaged with TBL delivery online and stated a preference for and satisfaction with this method. TPs valued opportunities to apply their knowledge in challenging scenarios and learn from discussions with their peers, the larger group, and facilitators. TBL was also perceived to be an engaging approach to learning and helped to maintain their interest with the teaching material. However, TPs struggled to engage with pre-work outside of the class due to competing work priorities.

Discussion
This study shows that online TBL was well accepted by TPs and can be successfully used to deliver education to large cohorts of learners. The model developed shows potential for scalability to larger numbers of learners.
Efficient least-squares reverse time migration in TTI media using a finite-difference solvable pure qP-wave equation
Authors: Mao Qiang , Huang Jianping , Mu Xinru , Zhang Zixiao , Zhang Yujian 
Published: March 2024

Abstract
The anisotropic characteristics of underground media play a crucial role in seismic wave propagation and should be accounted for during seismic imaging. The least-squares reverse time migration (LSRTM) method achieves ideal imaging results by suppressing migration artifacts and balancing amplitude. Therefore, pure quasi-P (P-qP) wave equations in tilted transversely isotropic (TTI) media have been widely used to implement LSRTM, owing to their ability to produce stable and noise-free wavefields. However, solving the anisotropic P-qP-wave equations typically necessitates the use of spectral-based methods, making them computationally inefficient, especially in 3D applications. In this study, we first develop a P-qP-wave equation in TTI media that can be efficiently computed through the finite-difference (FD) approach. Numerical tests show that, in comparison to the previous TTI P-qP-wave equation, the newly derived FD solvable TTI P-qP-wave equation yields reasonably accurate and highly efficient wavefield simulations. Then, building on our newly derived wave equation, we derive its adjoint migration and demigration operator to implement TTI LSRTM. Two synthetic examples suggest that the newly presented P-qP-wave TTI LSRTM approach effectively correct for the anisotropy effects, providing high-quality imaging results. Additionally, our approach has superior computational efficiency over the conventional P-qP-wave TTI LSRTM technique based on a hybrid FD pseudo-spectral (HFDPS) solver.
Doubly robust calibration of prediction sets under covariate shift
Authors: Yang Yachong , Kuchibhotla Arun Kumar , Tchetgen Tchetgen Eric 
Published: March 2024

Abstract
Conformal prediction has received tremendous attention in recent years and has offered new solutions to problems in missing data and causal inference; yet these advances have not leveraged modern semi-parametric efficiency theory for more efficient uncertainty quantification. We consider the problem of obtaining well-calibrated prediction regions that can data adaptively account for a shift in the distribution of covariates between training and test data. Under a covariate shift assumption analogous to the standard missing at random assumption, we propose a general framework based on efficient influence functions to construct well-calibrated prediction regions for the unobserved outcome in the test sample without compromising coverage.
Simultaneous false discovery proportion bounds via knockoffs and closed testing
Authors: Li Jinzhou , Maathuis Marloes H , Goeman Jelle J 
Published: March 2024

Abstract
We propose new methods to obtain simultaneous false discovery proportion bounds for knockoff-based approaches. We first investigate an approach based on Janson and Su’s k-familywise error rate control method and interpolation. We then generalize it by considering a collection of k values, and show that the bound of Katsevich and Ramdas is a special case of this method and can be uniformly improved. Next, we further generalize the method by using closed testing with a multi-weighted-sum local test statistic. This allows us to obtain a further uniform improvement and other generalizations over previous methods. We also develop an efficient shortcut for its implementation. We compare the performance of our proposed methods in simulations and apply them to a data set from the UK Biobank.
bHLH121 and clade IVc bHLH transcription factors synergistically function to regulate iron homeostasis in Arabidopsis thaliana
Authors: Gao Fei , Li Meijie , Dubos Christian 
Published: March 2024

Abstract
Iron is an essential micronutrient for plant growth and development. In Arabidopsis thaliana, an intricate regulatory network involving several basic helix–loop–helix (bHLH) transcription factors controls the homeostasis of iron. Among these transcription factors, bHLH121 plays a crucial role. bHLH121 interacts in vivo with clade IVc bHLH transcription factors and activates the expression of FIT and clade Ib bHLH transcription factors to stimulate the uptake of iron. How bHLH121 and clade IVc bHLH transcription factors function collectively and efficiently to maintain iron homeostasis is still unclear. Herein, we found that double loss-of-function mutants involving bhlh121 and one of the clade IVc bHLH transcription factors displayed more severe iron deficiency-associated growth defects than each of the single mutants. We also found that among the four clade IVc bHLH transcription factors, only bHLH34 and bHLH105 could partially complement the iron-associated growth defects of bhlh121 when overexpressed. These data, together with protein localization analysis, support that bHLH121 and clade IVc bHLH transcription factors act synergistically to regulate iron homeostasis and that different bHLH121/clade IVc and clade IVc/clade IVc protein complexes are involved in this process.
Ascorbate peroxidase in fruits and modulation of its activity by reactive species
Authors: Corpas Francisco J , González-Gordo Salvador , Palma José M 
Published: March 2024

Abstract
Ascorbate peroxidase (APX) is one of the enzymes of the ascorbate–glutathione cycle and is the key enzyme that breaks down H2O2 with the aid of ascorbate as an electron source. APX is present in all photosynthetic eukaryotes from algae to higher plants and, at the cellular level, it is localized in all subcellular compartments where H2O2 is generated, including the apoplast, cytosol, plastids, mitochondria, and peroxisomes, either in soluble form or attached to the organelle membranes. APX activity can be modulated by various post-translational modifications including tyrosine nitration, S-nitrosation, persulfidation, and S-sulfenylation. This allows the connection of H2O2 metabolism with other relevant signaling molecules such as NO and H2S, thus building a complex coordination system. In both climacteric and non-climacteric fruits, APX plays a key role during the ripening process and during post-harvest, since it participates in the regulation of both H2O2 and ascorbate levels affecting fruit quality. Currently, the exogenous application of molecules such as NO, H2S, H2O2, and, more recently, melatonin is seen as a new alternative to maintain and extend the shelf life and quality of fruits because they can modulate APX activity as well as other antioxidant systems. Therefore, these molecules are being considered as new biotechnological tools to improve crop quality in the horticultural industry.
Introducing the Condor Array Telescope – III. The expansion and age of the shell of the dwarf nova Z Camelopardalis, and detection of a second, larger shell
Authors: Shara Michael M , Lanzetta Kenneth M , Garland James T , Gromoll Stefan , Valls-Gabaud David , Walter Frederick M , Webb John K , Zurek David R , Brosch Noah , Rich R Michael 
Published: March 2024

ABSTRACT
The existence of a vast nova shell surrounding the prototypical dwarf nova Z Camelopardalis (Z Cam) proves that some old novae undergo metamorphosis to appear as dwarf novae thousands of years after a nova eruption. The expansion rates of ancient nova shells offer a way to constrain both the time between nova eruptions and the time for post-nova mass transfer rates to decrease significantly, simultaneously testing nova thermonuclear runaway models and hibernation theory. Previous limits on the expansion rate of part of the Z Cam shell constrain the inter-eruption time between Z Cam nova events to be &gt;1300 yr. Deeper narrow-band imaging of the ejecta of Z Cam with the Condor Array Telescope now reveals very low surface brightness areas of the remainder of the shell. A second, even fainter shell is also detected, concentric with and nearly three times the size of the ‘inner’ shell. This is the first observational support of the prediction that concentric shells must surround the frequently erupting novae of relatively massive white dwarfs. The Condor images extend our Z Cam imaging baseline to 15 yr, yielding the inner shell’s expansion rate as v = 83 ± 37 km s−1 at 23 deg south of west, in excellent agreement with our 2012 prediction. This velocity corresponds to an approximate age of $t = 2672^{-817}_{+2102}$ yr. While consistent with the suggestion that the most recent nova eruption of Z Cam was the transient recorded by Chinese imperial astrologers in the year 77 bce, the age uncertainty is still too large to support or disprove a connection with Z Cam.