bluuebunny/crossref_metadata_2025_split huggingface dataset:
Ocular complications in pediatric nephrotic syndrome treated with corticosteroids
Authors: L. Toruan Yulia Margareta , Trihono Partini Pudjihastuti , Sitorus Rita Sita , Dwipoerwantoro Pramita Gayatri 
Published: March 2024

Background Posterior subcapsular cataracts (PSC) and raised intraocular pressure (IOP) are the most common ocular complications of oral steroid administration, particularly following long-term use or treatment with high doses.
Objective To evaluate the association between cumulative steroid dose and duration of treatment with the occurrence of PSC and raised IOP, as well as its associated factors in children with idiopatic nephrotic syndrome (INS).
Methods This cross-sectional study included children aged 4–18 years with INS who received oral steroid therapy for at least six consecutive months. Patients underwent complete eye examinations by an ophthalmologist to evaluate their visual acuity as well as the occurrence of PSC and/or raised IOP. Results Of 92 subjects, 19.6% had PSC, 12% had raised IOP, and one had a best corrected visual acuity (BCVA) of <6/20. The median cumulative steroid dose was 12,161 (range 1,795–81,398) mg and median treatment duration was 23 (range 6–84) months. There were significant positive associations between cumulative steroid dose as well as treatment duration and the occurrence of PSC, with cut-off points of 11,475 mg and 24 months, respectively, as determined by receiver operator characteristic (ROC) curves. Females were four times more likely to have PSC compared to males (PR 4; 95%CI 1.57 to 13.38; P=0.001). Cumulative steroid dose and duration of treatment were not associated with raised IOP.
Conclusion Cumulative steroid dose of 11,475 mg or higher and/or duration of steroid therapy of 24 months of more were significantly associated with the occurrence of PSC, but not with raised IOP.
Cognitive function in Indonesian children with type 1 diabetes mellitus
Authors: Ulfa Marselya , Aditiawati Aditiawati , Hasanah Yulisnawati , Dhaini Shafri , Bakrie Achirul , Indra Raden Muhammad 
Published: March 2024

Background Children with type 1 diabetes mellitus (T1DM) are at risk of cognitive impairment. While the pathophysiology is still unclear, cognitive impairment in children with T1DM can result in significant negative effects on quality of life.
Objective to evaluate the cognitive function of Indonesian children with T1DM and its association with glycemic control and to identify factors affecting cognitive function in children with T1DM.
Methods The cognitive function of children aged 6 years or older with T1DM was measured using the Wechsler Intelligence Scale for Children-Revised (WISC-R). We analyzed for potential associations between cognitive function and glycemic control based on mean HbA1c levels and other factors, such as the age of onset, duration of illness, and maternal educational attainment. We also identified failure to achieve age-appropriate results on any of the WISC-R subtests (cognitive impairment) and associated factors.
Results A total of 46 subjects were included in this study, with a mean age of 12.8 (SD 3.4) years. There were 27 (58.7%) girls and 19 (41.3%) boys. Subjects’ mean full-scale IQ (FSIQ) was 91.35 (SD 11.43). A moderate negative correlation was found between FSIQ and mean HbA1c levels (r=-0.43; P<0.01). Children with mothers who had university degrees had significantly higher IQs (mean difference 7.39; 95%CI 3.10 to 13.66; P=0.02) than those with mothers without degrees. Failure of any WISC-R subtest was noted in 34 subjects, consisting of 17 verbal, 1 performance, and 34 verbal and performance subtests. A higher proportion of those with cognitive impairment had mean HbA1c >10%. However, compared to those with mean HbA1c ?10, the difference did not reach a statistical significance (OR 5.0; 95%CI 0.95 to 26.31; P=0.50)
Conclusion Glycemic control and maternal educational attainment are associated with cognitive function in Indonesian children with T1DM. Poor glycemic control is also associated with a higher risk of cognitive impairment.
DPP‐4 inhibitor sitagliptin treatment results in altered myocardial metabolic proteome and oxidative phosphorylation in a swine model of chronic myocardial ischemia
Authors: Harris Dwight D. , Sabe Sharif A. , Broadwin Mark , Bellam Krishna , Xu Cynthia M. , Li Janelle W. , Abid M. Ruhul , Sellke Frank W. 
Published: March 2024

AbstractSmall animal models have shown improved cardiac function with DPP‐4 inhibition, but many human studies have shown worse outcomes or no benefit. We seek to bridge the gap by studying the DPP‐4 inhibitor sitagliptin in a swine model of chronic myocardial ischemia using proteomic analysis. Thirteen Yorkshire swine underwent the placement of an ameroid constrictor on the left coronary circumflex artery to model chronic myocardial ischemia. Two weeks post‐op, swine received either sitagliptin 100 mg daily (SIT, n = 5) or no drug (CON, n = 8). After 5 weeks of treatment, swine underwent functional measurements and tissue harvest. In the SIT group compared to CON, there was a trend towards decreased cardiac index (p = 0.06). The non‐ischemic and ischemic myocardium had 396 and 166 significantly decreased proteins, respectively, in the SIT group compared to CON (all p < 0.01). This included proteins involved in fatty acid oxidation (FAO), myocardial contraction, and oxidative phosphorylation (OXPHOS). Sitagliptin treatment resulted in a trend towards decreased cardiac index and decreased expression of proteins involved in OXPHOS, FAO, and myocardial contraction in both ischemic and non‐ischemic swine myocardium. These metabolic and functional changes may provide some mechanistic evidence for outcomes seen in clinical studies.
Platform margin belt structure and sedimentation characteristics of Changxing Formation reefs on both sides of the Kaijiang-Liangping trough, eastern Sichuan Basin, China
Authors: Zuo Mingtao , Wang Jiangong , Sun Xiujian , Hu Zhonggui , Bai Yadong , Yang Wei , Li Hongzhe 
Published: March 2024

Abstract
This article discusses the types and characteristics of platform margin belts on both sides of the Kaijiang-Liangping trough in the Sichuan Basin during the Late-Permian Changhsingian age combined with the seismic reflection characteristics. The results show that there are four types of platform margin belts on both sides of the Kaijiang-Liangping trough: (1) steep-slope, single-platform margin belts controlled by faults; (2) steep-slope, single-platform margin belts controlled by paleogeomorphology; (3) steep-slope, multiple-platform margin belts controlled by paleogeomorphology; and (4) gentle-slope, multiple-platform margin belts controlled by paleogeomorphology. Reefs developed in the different types of platform margin belts exhibit different morphological characteristics and stacking patterns. Among all the reefs that developed in steep-slope, platform marginal belts are mainly characterized by aggradational accretion and different degrees of lateral migration in different directions. In contrast, the reefs developed in gentle-slope platform margin belts show distinctive characteristics of multiple bandings and lateral extension. Research suggests that the differences in the platform margin belts’ structure and reefs’ development rules are jointly controlled by a combination of syn-sedimentary fault activities, paleogeomorphology, and sea-level fluctuations. These results can be used to explore and predict reef reservoirs on carbonate platform margins.
Effect of ladle-lining materials on inclusion evolution in Al-killed steel during LF refining
Authors: Gao Fu-bin , Yan Xinbo , Wang Fuming , Wang Xinhua , Li Jianli 
Published: March 2024

Abstract
The effect of lining materials (Al2O3 and Al2O3–MgO·Al2O3) of ladle on evolution of non-metallic inclusions in aluminum-killed (Al-killed) steel during ladle furnace refining without Ca treatment was investigated through industrial experiments. The results showed that non-metallic inclusions experienced the changes from Al2O3 → MgO–Al2O3 → CaO–Al2O3. During the refining process using either of the two ladle lining materials, for all non-metallic inclusions, the vast majority are distributed in the high Al2O3 area of the CaO–Al2O3–MgO phase diagram, with very little or none in the low melting point zone. Non-metallic inclusions are mainly smaller than 3 μm, while those larger than 3 μm consisted primarily of MgO·Al2O3 and CaO–Al2O3 inclusions. The use of an Al2O3–MgO·Al2O3-lining ladle is more effective in reducing the number density of inclusions in the steel. However, during the refining process, the Al2O3-lining ladle does not have a significant impact on the presence of MgO–Al2O3 and CaO–Al2O3 inclusions in the molten steel. The Al2O3–MgO·Al2O3-lining ladle does not have a significant effect on MgO–Al2O3 inclusions, but it does promote the formation of CaO–Al2O3 and CaS inclusions in the molten steel.
Enhanced strength of (CoFeNiMn)100−xCrx (x = 5, 20, 35 at.%) high entropy alloys via formation of carbide phases produced from industrial-grade raw materials
Authors: Polat Gökhan 
Published: March 2024

Abstract
(CoFeNiMn)100−xCrx (x = 5, 20, 35 at.%) HEAs were produced using vacuum arc melting followed by suction casting using industrial-grade raw materials and subsequent annealing at 1150 °C for 24 h. The increasing Cr content triggered the formation of the Cr7C3 in the FCC matrix due to the presence of C impurity in the raw materials. The increasing Cr content from 5 to 35 at.% raised the hardness from 206 (±7) to 383 (±4) HV and yield strength from 210 to 350 MPa due to the embedded Cr7C3 phases in the matrix. The HEA consists of 20 at.% Cr was found to be the most promising alloy due to the strength-ductility trade-off with the values of 350 MPa compressive yield strength and 10.7 % strain. The enhanced mechanical properties of the HEAs by using industrial-grade low-cost raw materials could make them more attractive materials for industrial applications.
Powder metallurgy processing of high entropy alloys: Bibliometric analysis and systematic review
Authors: Akinwekomi Akeem Damilola , Bamisaye Olufemi Sylvester , Bodunrin Michael Oluwatosin 
Published: March 2024

Abstract
Research attention in powder metallurgy (PM) processing of high-entropy alloys (HEAs) is rising. Some reviews have been published but a detailed historical analysis to identify the thematic research areas and prospective future research areas is lacking. Therefore, this study presents a bibliometric literature analysis of PM-processed HEAs by mapping and clustering 700 articles published between 2007 and August 2022 in the Scopus database. The most prolific authors, their collaborators, institutions, and most preferred journals publishing PM-HEA works are identified and mapped. Publication trend shows that significant research attention in the PM processing of HEAs began to gain traction in 2016. The top three journals in this field are Journal of Alloys and Compounds, Materials Science and Engineering A, and Intermetallics. However, co-authorship network analysis does not reveal significant inter-institutional research collaboration indicating that strengthening this area could help to accelerate scientific discovery, enhance technology transfer, and commercialization of HEA products. Based on the co-occurrence frequencies of author keywords, popular research directions are identified, and a systematic review of emerging functional applications is undertaken. This work provides a comprehensive visual reference guide for researchers to deepen their knowledge of this field and delivers insight into prospective future research opportunities to stimulate further ground-breaking works.
Comparison of different iron oxides for degradation of tetracycline anti-bacterial drug
Authors: Velayudan Radhakrishnan , Natarajan Jeyakumaran 
Published: March 2024

Abstract
Nanomaterials have a wide range of applications including novel biomedical studies are devoted to improving the functionality and effectively of traditional and unmodified systems, both drug carriers and common scaffolds for tissue engineering or advanced hydrogels for wound healing purposes. In this regard, metal oxide nanoparticles show great potential as versatile tools in biomedical science. In particular, iron oxide nanoparticles with different shape and sizes hold outstanding physiochemical characteristics, such as high specific area and structure that make them unique nanomaterials to be used in diverse aspects of medicine and biological systems. The challenges associated with the uncontrolled presence of antibiotics such as tetracycline in the environment have necessitated their removal through different techniques. Tetracycline is hard to degrade in living organisms and can even be converted to more toxic substances. In this article different type of iron oxides were subjected to photo degradation of antibacterial drug Tetracycline under UV light illumination and direct sunlight and the results were promising to degrade the drug within 20 min. The SEM, TEM, EDAX and XRD for the catalyst were characterized to confirm the presence of iron oxide, the size and shape of the particle. The kinetics of photo degradation of tetracycline followed the pseudo-first-order mechanism, proceeding through hydroxyl radicals generated under illumination. Moreover, the photo generated hydrogen peroxide could lead to heterogeneous photocatalytic processes on the surface of iron oxide nanoparticles; additionally generating hydroxyl and hydroperoxyl radicals enables photo degradation of tetracycline.
Municipal Tax Policy in State Emergencies
Authors: Dowgier Rafał , Olechno Artur , Grabowska Sabina 
Published: March 2024

Abstract
A significant part of the revenue supplying municipal budgets in Poland comes from taxes that are subject to municipalities’ constitutionally enshrined powers. This income is mainly generated by contributions connected with the right of property ownership, among others. Apart from a fiscal function, taxes may also stimulate specific processes. Positive stimulation within the scope of tax policy is mainly based on various types of tax preferences. They may be applied as a tool of tax policy which fulfils specific economic and social objectives. These issues have become particularly important during emergencies taking place in the state, such as the COVID-19 pandemic, the migration crisis or the war in Ukraine. In the wake of the recent occurrence of such types of quasi-extraordinary measures, it is reasonable to ask a question about the need to adjust the legal limits of municipal tax powers in this regard. Concurrently, the necessity to maintain balance between support provided to specific categories of entities and the financial needs of municipalities may not escape notice. The Polish experience shows that as a consequence of emergencies, ad hoc solutions of a merely occasional nature have been introduced to the tax law system. Hence a thesis may be formulated according to which it is reasonable to approach this kind of phenomenon in a systemic way, which should be reflected in the introduction of standard and stable tools that could enable municipalities to undertake specific action. The purpose of this study is to verify this assumption, relying, most of all, on the experiences and needs that have emerged in Poland in recent years.
The EU’s Emergency Intervention against High Energy Prices: Implications for the Visegrad Group Countries
Authors: Šipoš Tomáš , Karfíková Marie 
Published: March 2024

Abstract
The energy market in the European Union has recently faced significant external influences, which have resulted in turbulent developments in wholesale energy markets. The extraordinary and sudden increase in electricity prices and the imminent risk of further increases required a joint solution by the Member States at the end of 2022. On 6 October 2022, the Council of the European Union adopted Regulation 2022/1854 on Emergency Intervention to Address High Energy Prices, which establishes an emergency intervention to mitigate the effects of high energy prices through exceptional, targeted and time-limited measures. In this paper, the authors focus on the legal framework adopted to introduce the mandatory cap on market revenues to electricity producers in the countries of the Visegrad Group (the Czech Republic, Hungary, Poland and Slovakia).
MODEL KOMUNIKASI SISWA JURUSAN KREASI DESAIN MODE PADA PELAKSANAAN MAGANG ERA NEW NORMAL
Authors: GUNARIAN NATHALIA , PITHALOKA HANNA , FAUZIAH NABILAH SARAH 
Published: March 2024

Abstract. Studi ini untuk mengetahui Pola Komunikasi yang digunakan Mahasiswi Kreasi Desain Mode pada pelaksanaan magang periode October – Januari 2023 yang dilakukan saat era new normal. Penelitian ini bertujuan untuk mengungkapkan kendala komunikasi yang dialami siswa magang serta solusi yang ditawarkan. Teori Lasswell’s digunakan sebagai konsep studi (siapa, berbicara apa, media apa, kepada apa dan dampak yang ditimbulkan). Peneliti menggunakan metodologi penelitian survey, dengan menggunakan data internal laporan magang dan survey pilihan berganda serta pertanyaan terbuka yang di distribusikan setelah periode magang berakhir. Penelitian ini berlokasi in Jakarta dan melibatkan banyak 31 siswa. Di industri mode, peneliti membagi menjadi 4 tahapan: (pra) konseptual , produksi, evet dan pasca event. Hasilnya adalah siapa dan untuk siapa mengacu kepada. peranan siswa sebagai komunikator atau komunikan atau penerima tergantung dari tahapan dan deskripsi perkerjaan yang mereka tangani serta dengan pihak mitra atau stakeholders siapa siswa berhadapan. Adapun komunikasi dua arah yang digunakan siswa magang. Berbicara apa dan dampak yang ditimbulkan mengacu kepada jenis pesan informatif dan persuasif yang digunakan siswa sesuai dengan kepentingan mitra atau stakeholders terkait yang ingin dicapai. Whatsapp pertama dan tatap muka kedua merupakan merupakan dua media yang banyak digunakan saar periode era new normal tersebut.
Kata Kunci: Model Komunikasi, Kreasi Mode, Magang
Digitales Selbstbevorzugungsverbot im Missbrauchsrecht: Müssen Plattformen den Wettbewerber doch zum eigenen Nachteil fördern?
Authors: Bodenstein Ines , Zinndorf Sarah 
Published: March 2024

Zusammenfassung
Die Selbstbevorzugung oder das sog. „Self-preferencing“ ist eine Missbrauchskategorie, der immer mehr Aufmerksamkeit in den Verfolgungsprioritäten der Europäischen Kommission oder nationaler Kartellbehörden zukommt. Zentrale Fälle sind die Verfahren der Europäischen Kommission i. S. Google Shopping und Amazon Marketplace und Buy Box. Aber auch die frühen Microsoft-Fälle können unter eine Theorie der Selbstbevorzugung fallen. Dem Verbot der Selbstbevorzugung steht der Grundsatz gegenüber, dass prinzipiell auch für ein marktbeherrschendes Unternehmen keine Pflicht zur Förderung fremden Wettbewerbs besteht. Dies führt zu einem erheblichen Maß an Rechtsunsicherheit in der Praxis bei der Bewertung von Selbstbevorzugungsfällen über die konkret entschiedenen Verfahren und über die inzwischen erfolgte (Quasi)-Regulierung in DMA und § 19a GWB hinaus. In diesem Beitrag soll deswegen versucht werden, aus den zentralen Fällen zur Selbstbevorzugung allgemeine Beurteilungskriterien für das klassische Missbrauchsrecht abzuleiten.
Mykola Makarenko and Mariupol Neolithic Burial Ground The tragic fates of the archaeologist and the site
Authors: Mykhailova Nataliia 
Published: March 2024

Mariupol Neolithic burial site, unique by its exclusive rich and diversiform inventory, was excavated by Ukrainian archaeologist and art critic Mykola Makarenko in 1930. The author of the excavations was executed by Soviet punitive authorities. The top-level and highly informative publication of the materials on the cemetery, made in 1933, was confiscated. Part of the burial inventory was taken to Russia. Anthropological materials were destroyed during World War II.The tragedy of Mariupol Cemetery continued in 2022. This was the year which became the tragedy in the history of Ukraine and inherently influenced the history of Europe. The Ukrainian people, the Ukrainian nature, and the Ukrainian culture suffered irretrievable losses. So did Ukrainian archaeology.Hundreds of archaeological sites in the war zone, in the zone of occupation and in the annexed territories were completely destroyed or irreparably damaged. Among them, there were the scant surviving artifacts from Mariupol Cemetery.This article is devoted to the history of excavations of Mariupol Burial Complex and the tragic fate of the collection of artifacts.
PEMANFAATAN HASIL FERMENTASI LINDI DENGAN KONSENTRASI YANG BERBEDA TERHADAP PERTUMBUHAN DAN KEPADATAN SEL Chlorella sp.
Authors: Rosyadi Rosyadi , Agusnimar Agusnimar , Hadi Khairul 
Published: March 2024

Lindi merupakan limbah cair yang kaya akan nutrisi, yang dapat digunakan sebagai sumber bahan organik untuk kultur mikroalga seperti jenis Chlorella sp. Penelitian ini bertujuan untuk mengetahui pemanfaatan hasil fermentasi lindi tanpa disaring dengan konsentrasi berbeda terhadap kelimpahan sel Chlorella sp. Penelitian dilakukan di laboratorium Mikroalga dan Nutrisi Ikan Fakultas Pertanian Universitas Islam Riau, Pekanbaru. Metode yang digunakan dalam penelitian ini adalah metode eksperimen, Rancangan Acak Lengkap (RAL), dengan 1 taraf dan 5 perlakuan serta 3 ulangan. Adapun perlakuan yang digunakan adalah konsentrasi lindi meliputi, P1=5%, P2=10%, P3=15%, P4=20% dan P5=25%/L air. Organisme uji dalam penelitian ini adalah mikroalga jenis Chlorella sp. dan wadah kultur yang digunakan galon dengan kapasitas 20 L dengan volume air 16 L, sedangkan lindi yang digunakan sebagai bahan uji diambil dari TPA Muara Fajar Pekanbaru. Parameter yang diukur adalah kelimpahan sel Chlorella sp, laju pertumbuhan spesifik, biomassa dan kualitas air. Hasil yang diperoleh menunjukkan kelimpahan Chlorella sp. tertinggi pada konsentrasi 10% sebesar 3.077.778 sel/ml, dan puncak pada hari ke-6, konsentrasi terendah konsentrasi 25%, sebesar 2.016.667 sel/ml puncak hari ke-8, laju pertumbuhan spesifik tertinggi pada konsentrasi 10% sebesar 0,197/hr serta biomassa tertinggi sebesar 0,28 g/L.Leachate is a liquid waste the result of the decomposition of organic waste originating from landfills that is rich in nutrients, which can be used as a source of organic matter for cultures Chlorella sp. This study aims to determine utilization of fermented leachate with different concentrations on the growth and cell density of Chlorella cells. The method used was an experimental design, Completely Randomized Design (CRD), with 5 treatments and 3 replication. The treatment were the concentration of leachate, mainly: P1=5%, P2=10%, P3=15%, P4=20% and P5=25%. The test organism in this study was Chlorella sp. The culture container used were gallons with a capacity of 20 L, leachate obtained from Muara Fajar landfill in Pekanbaru. The parameters measured were the cell density of Chlorella sp. cells, specific growth rate, and water quality. The results showed that cell density of Chlorella sp. was the highest at treatment P2 (10% concentration) of 307,78 cells mL, lowest treatment P2 (25% concentration) of 201,67 cells ml-1. The highest specific growth rate was 10% concentration of 0.197 cells mL day, and the lowest was at a 25% leachate concentration of 0.144 cells ml-1 day-1. From this research, it can be concluded that the best utilization of leachate fermentation results was obtained in the P2 treatment (10% concentration). Therefore, the recommended concentration for culturing Chlorella sp. namely a concentration of 10% in treatment P2.