bluuebunny/crossref_metadata_2025_split huggingface dataset:
Zum Einsatz von Verpresspfählen an Stelle von Verpressankern zur Rückverankerung von Spundwänden
Authors: Quast Arne , Milzner Thorsten , Thieken Klaus , Achmus Martin 
Published: June 2008

AbstractSeit einiger Zeit werden häufig Verpresspfähle statt Verpressanker für die Rückverankerung von Spundwänden eingesetzt. Diese werden meist in gleicher Weise wie Verpressanker gemäß DIN 4125 eignungsgeprüft. Es wird das Tragverhalten von Verpresspfählen und Verpressankern in Sandböden während der Prüfung und im Gebrauchszustand untersucht und verglichen. Zunächst wird auf die statische Wirkungsweise von Verpressankern sowie Verpresspfählen eingegangen und deren Unterschiede im Tragverhalten kurz beschrieben. Daneben wird der aktuelle Stand der Normung vorgestellt. Schließlich werden mit der Finite‐Elemente‐Methode erhaltene Ergebnisse dargestellt. Verpresspfähle zeigen bei der Probebelastung ein signifikant anderes, nämlich deutlich günstigeres Tragverhalten als im Endzustand. Wesentlicher Grund dafür ist, dass bei der Probebelastung im Gegensatz zum Endzustand innerhalb des Gleitkeils Kräfte in den Boden übertragen werden, was durch eine Verspannung zwischen Wand und Boden durch die Abstützung der Prüfpresse gegen die Spundwand noch verstärkt wird. Diese Effekte sind bei der Auswertung einer Verpresspfahlprüfung unbedingt zu berücksichtigen.
Nachweis der Sicherheit gegen Aufschwimmen bei Baugruben mit verankerten Betonsohlen
Authors: Hettler Achim , Morgen Karl 
Published: June 2008

AbstractAusgangspunkt für den folgenden Beitrag waren Diskussionen im Arbeitskreis 2.1 “Pfähle” über die Nachweise bei Baugruben mit verankerten Betonsohlen, die unter Auftrieb stehen. Eine der Hauptfragen ist die Einleitung von seitlichen Kräften in die Sohle und deren Verteilung. Bei den in der Regel unbewehrten Sohlen ist nur für den Sonderfall von relativ schmalen und dicken Konstruktionen eine gleichmäßige Verteilung über die gesamte Breite möglich. Bei breiten Baugruben mit relativ dünnen Sohlen ist zwischen dem Mittelbereich, wo nur das Eigengewicht und rückhaltende Kräfte dem Auftrieb entgegenwirken, und dem Randbereich, wo seitliche Kräfte angesetzt werden dürfen, zu unterscheiden. Der Beitrag berücksichtigt den neuesten Stand der DIN 1054. Alle wesentlichen Fragen werden ausführlich diskutiert und in einem Beispiel erläutert.
Integration of enzyme, strain and reaction engineering to overcome limitations of baker's yeast in the asymmetric reduction of α‐keto esters
Authors: Kratzer Regina , Egger Sigrid , Nidetzky Bernd 
Published: June 2008

AbstractWe report on the development of a whole‐cell biocatalytic system based on the popular host Saccharomyces cerevisiae that shows programmable performance and good atom economy in the reduction of α‐keto ester substrates. The NADPH‐dependent yeast reductase background was suppressed through the combined effects of overexpression of a biosynthetic NADH‐active reductase (xylose reductase from Candida tenuis) to the highest possible level and the use of anaerobic reaction conditions in the presence of an ethanol co‐substrate where mainly NADH is recycled. The presented multi‐level engineering approach leads to significant improvements in product optical purity along with increases in the efficiency of α‐keto ester reduction and co‐substrate yield (molar ratio of formed α‐hydroxy ester to consumed ethanol). The corresponding α‐hydroxy esters were obtained in useful yields (>50%) with purities of ≥99.4% enantiomeric excess. The obtained co‐substrate yield reached values of greater than 1.0 with acetate as the only by‐product formed. Biotechnol. Bioeng. © 2008 Wiley Periodicals, Inc.
Enhanced differentiation of embryonic stem cells using co‐cultivation with hepatocytes
Authors: Moore Rebecca N. , Dasgupta Anouska , Rajaei Nayyereh , Yarmush Martin L. , Toner Mehmet , Larue Lionel , Moghe Prabhas V. 
Published: June 2008

AbstractWe examined the effects of co‐cultivated hepatocytes on the hepatospecific differentiation of murine embryonic stem (ES) cells. Utilizing an established mouse ES cell line expressing high or low levels of E‐cadherin, that we have previously shown to be responsive to hepatotrophic growth factor stimulation (Dasgupta et al., 2005. Biotechnol Bioeng 92(3):257–266), we compared co‐cultures of cadherin‐expressing ES (CE‐ES) cells with cultured rat hepatocytes, allowing for either paracrine interactions (indirect co‐cultures) or both juxtacrine and paracrine interactions (direct co‐cultures, random and patterned). Hepatospecific differentiation of ES cells was evaluated in terms of hepatic‐like cuboidal morphology, heightened gene expression of late maturation marker, glucose‐6‐phosphatase in relation to early marker, alpha‐fetoprotein (AFP), and the intracellular localization of albumin. Hepatocytes co‐cultured with growth factor primed CE‐ES cells markedly enhanced ES cell differentiation toward the hepatic lineage, an effect that was reversed through E‐cadherin blockage and inhibited in control ES cells with reduced cadherin expression. Comparison of single ES cell cultures versus co‐cultures show that direct contact co‐cultures of hepatocytes and CE‐ES cells maximally promoted ES cell commitment towards hepatodifferentiation, suggesting cooperative effects of cadherin‐based juxtacrine and paracrine interactions. In contrast, E‐cadherin deficient mouse ES (CD‐ES) cells co‐cultured with hepatocytes failed to show increased G6P expression, confirming the role of E‐cadherin expression. To establish whether albumin expression in CE‐ES cells was spatially regulated by co‐cultured hepatocytes, we co‐cultivated CE‐ES cells around micropatterned, pre‐differentiated rat hepatocytes. Albumin localization was enhanced “globally” within CE‐ES cell colonies and was inhibited through E‐cadherin antibody blockage in all but an interfacial band of ES cells. Thus, stem cell based cadherin presentation may be an effective tool to induce hepatotrophic differentiation by leveraging both distal/paracrine and contact/juxtacrine interactions with primary cells of the liver. Biotechnol. Bioeng. © 2008 Wiley Periodicals, Inc.
One‐Pot Oxidative Esterification and Amidation of Aldehydes
Authors: Ekoue‐Kovi Kekeli , Wolf Christian 
Published: June 2008

AbstractDuring recent years, the direct transformation of aldehydes into esters or amides has developed into a vigorous research area and powerful one‐pot oxidative esterification and amidation procedures have been reported. Several concepts that are often complementary in substrate scope, functional group tolerance, and reaction outcome have emerged, thus providing a wide range of alternatives to classical ester and amide synthesis via carboxylic acid intermediates.
Synthesis and Crystal Structure of the New High‐Pressure Phase CdB2O4
Authors: Knyrim Johanna S. , Emme Holger , Döblinger Markus , Oeckler Oliver , Weil Matthias , Huppertz Hubert 
Published: June 2008

AbstractThe use of high‐pressure/high‐temperature conditions (7.5 GPa and 1100 °C; Walker‐type multianvil apparatus) led to the synthesis of a new cadmium borate CdB2O4, starting from stoichiometric mixtures of the oxides. The crystal structure was determined on the basis of single crystal X‐ray diffraction data, to reveal the hexagonal space group P63 with a=885.2(2), c=716.72(8) pm, Z=8, R1=0.0178, and wR2=0.0388 (all data). CdB2O4 is built up from interconnected layers of BO4‐tetrahedra and exhibits for the first time the basic structure of a family of compounds, represented by BaGa2O4, KAlSiO4, KGeAlO4, KCoPO4, CaP2N4 and the recently discovered SrP2N4. The lack of superstructure ordering in CdB2O4 was confirmed by electron diffraction. Additionally, a BOB angle of 180° was found in this borate for the first time.
Predicting disease progression after nephrectomy for localized renal cell carcinoma: The utility of prognostic models and molecular biomarkers
Authors: Crispen Paul L. , Boorjian Stephen A. , Lohse Christine M. , Leibovich Bradley C. , Kwon Eugene D. 
Published: June 2008

AbstractDisease progression after nephrectomy for pathologically localized renal cell carcinoma (RCC) is associated with a significant mortality rate, given the limited efficacy of available treatment regimens for metastatic disease. As such, several adjuvant trials have been designed to treat patients at particularly high risk for postsurgical RCC progression. Several different prognostic models designed to identify patients at high risk of disease progression are available. Although these available predictive models provide a reasonable assessment of patients' risks of disease progression, the accuracy of these models may further be improved via the incorporation of molecular prognostic biomarkers. Although numerous candidate molecules have been described, few have been specifically assessed for the association with disease progression after nephrectomy. IMP‐3, CXCR3, p53, Survivin, cIAP1, B7‐H1, and B7‐H4 have all been associated with disease progression after nephrectomy. The incorporation of 1 or several of these biomarkers may increase the accuracy of currently available prognostic models and thereby facilitate the appropriate use of adjuvant therapies aimed at preventing future disease progression. As such, the authors review the current prognostic tools for predicting disease progression for localized RCC, and detail studies to date that have evaluated various biomarkers in this setting. Cancer 2008. © 2008 American Cancer Society.
On probabilistic yielding of materials
Authors: Jeremić Boris , Sett Kallol 
Published: June 2008

AbstractUncertainty in material properties can have large effect on numerical modeling of solids and structures. This is particularly true as all natural and man‐made materials exhibit spatial non‐uniformity and point‐wise uncertainty in their behaviors.A methodology that accounts for the probabilistic yielding of elastic–plastic materials is presented. The recently developed Eulerian–Lagrangian form of the Fokker–Planck–Kolmogorov equation is used to obtain a second‐order exact solution to elastic–plastic constitutive differential equations. In this paper that solution is used in deriving the weighted probabilities of elastic, elastic–plastic behavior and yielding. A number of examples for two commonly used material models, von Mises and Drucker–Prager, illustrated the findings. Copyright © 2008 John Wiley & Sons, Ltd.
A stabilized smoothed finite element method for free vibration analysis of Mindlin–Reissner plates
Authors: Nguyen‐Xuan H. , Nguyen‐Thoi T. 
Published: June 2008

AbstractA free vibration analysis of Mindlin–Reissner plates using the stabilized smoothed finite element method is studied. The bending strains of the MITC4 and STAB elements are incorporated with a cell‐wise smoothing operation to give new proposed elements, the mixed interpolation and smoothed curvatures (MISCk) and SMISCk elements. The corresponding bending stiffness matrix is computed along the boundaries of the smoothing elements (smoothing cells). Note that shearing strains and the shearing stiffness matrix of the proposed elements are unchanged from the original elements, the MITC4 and STAB elements. It is confirmed by numerical tests that the present method is free of shear locking and has the marginal improvements compared with the original elements. Copyright © 2008 John Wiley & Sons, Ltd.
A metadata management framework for dynamic information integration
Authors: Göres Jürgen , Dessloch Stefan 
Published: June 2008

AbstractOne necessary factor in the success of data grid technology to share structured and semi‐structured data across organizational boundaries is the availability of convenient, easy‐to‐use information integration services that provide an application‐specific, integrated view over the relevant data sources. To deal with the many challenges of information integration in such a dynamic environment, the integrated handling of metadata is an essential factor. In this paper, we present the PALADIN integration framework, a platform providing the common infrastructure on top of which the different integration services can be built. Copyright © 2008 John Wiley & Sons, Ltd.
Parallel tiled QR factorization for multicore architectures
Authors: Buttari Alfredo , Langou Julien , Kurzak Jakub , Dongarra Jack 
Published: June 2008

AbstractAs multicore systems continue to gain ground in the high‐performance computing world, linear algebra algorithms have to be reformulated or new algorithms have to be developed in order to take advantage of the architectural features on these new processors. Fine‐grain parallelism becomes a major requirement and introduces the necessity of loose synchronization in the parallel execution of an operation. This paper presents an algorithm for the QR factorization where the operations can be represented as a sequence of small tasks that operate on square blocks of data (referred to as ‘tiles’). These tasks can be dynamically scheduled for execution based on the dependencies among them and on the availability of computational resources. This may result in an out‐of‐order execution of the tasks that will completely hide the presence of intrinsically sequential tasks in the factorization. Performance comparisons are presented with the LAPACK algorithm for QR factorization where parallelism can be exploited only at the level of the BLAS operations and with vendor implementations. Copyright © 2008 John Wiley & Sons, Ltd.
Towards a Noah's ark for the upcoming data deluge
Authors: Bassi Alessandro , Denazis Spyros , Giacomin Pierpaolo 
Published: June 2008

AbstractIn this paper, we would like to present our work about a framework to manage the massive quantity of data that services and application will be handling in the future. The ever‐growing need for data is already pushing the current infrastructure to the limit, and we believe that mechanisms developed for a totally different kind and size of traffic will not be able to cope with upcoming requests. Data grids seem to provide a sustainable architecture for the data‐hungry application needs, allowing the development of high‐performance solutions, although no current solution seems to have found the silver bullet yet. We would like to present our ideas about how to solve this problem, argumenting why we need a copernican revolution to the way we look at network and storage. The approach we will be presenting is layered, going from a new generation of network devices to a standard interface to applications and services, passing through a novel middleware based on peer‐to‐peer concepts and a stack of data transfer protocols. Copyright © 2008 John Wiley & Sons, Ltd.
Head region of unconventional myosin I family members is responsible for the organ‐specificity of their roles in left–right polarity in Drosophila
Authors: Hozumi Shunya , Maeda Reo , Taniguchi‐Kanai Maiko , Okumura Takashi , Taniguchi Kiichiro , Kawakatsu Yasuhiro , Nakazawa Naotaka , Hatori Ryo , Matsuno Kenji 
Published: June 2008

AbstractIn Drosophila, Myosin31DF (Myo31DF), encoding a Myosin ID protein, has crucial roles in left–right (LR) asymmetric development. Loss of Myo31DF function leads to laterality inversion for many organs, including the embryonic gut. Here, we found that Myo31DF was required before LR asymmetric morphogenesis in the hindgut, suggesting it functions in LR patterning instead of directly in hindgut morphological changes. Myosin61F (Myo61F) encodes another Myosin I, and Myo31DF or Myo61F overexpression reverses the laterality of different organs. Myo31DF and Myo61F have domains conserved in Myosin proteins, particularly in the proteins' head regions. We studied the roles of these domains in LR patterning using overexpression analysis. The Actin‐binding and ATP‐binding domains were essential for both proteins, but the IQ domains, binding sites for Myosin light chains, were required only by Myo31DF. Our results also suggest that the organ specificities of the Myo31DF and Myo61F activities depended on their head regions. Developmental Dynamics 237:3528–3537, 2008. © 2008 Wiley‐Liss, Inc.
The representation and processing of familiar faces in dyslexia: differences in age of acquisition effects
Authors: Smith‐Spark James H. , Moore Viv 
Published: June 2008

AbstractTwo under‐explored areas of developmental dyslexia research, face naming and age of acquisition (AoA), were investigated. Eighteen dyslexic and 18 non‐dyslexic university students named the faces of 50 well‐known celebrities, matched for facial distinctiveness and familiarity. Twenty‐five of the famous people were learned early in life, while the remaining 25 were first encountered more recently. There was no overall difference between the dyslexics and the non‐dyslexics in the speed or the accuracy with which they named faces, suggesting that face naming is unimpaired in dyslexic adults. In keeping with previous findings, the results indicated a speed and accuracy advantage for early‐acquired over late‐acquired faces. In addition, a significant participant group × AoA interaction demonstrated that the non‐dyslexic group was significantly faster to name early‐ than late‐acquired faces, while the dyslexic group showed a much smaller and non‐significant effect of AoA. The results suggest that there are differences in representation in dyslexia and that these may be linked to problems with attentional/executive function and automaticity. It is proposed that a more fine‐grained approach to investigating dyslexia in adulthood should be adopted, in order to uncover cognitive as well as behavioural differences between dyslexics and non‐dyslexics. Copyright © 2008 John Wiley & Sons, Ltd.
Characteristics and key findings for ‘Neuraminidase inhibitors for preventing and treating influenza in children’
Authors: van Dalen E. C. , Kremer L. C. M. 
Published: June 2008

AbstractThese are the characteristics and key findings for a Cochrane review published in this issue of EBCH, first published as: Matheson NJ, Harnden AR, Perera R, Sheikh A, Symmonds‐Abrahams M. Neuraminidase inhibitors for preventing and treating influenza in children. Cochrane Database of Systematic Reviews 2007, Issue 1. Art. No.: CD002744. DOI: 10.1002/14651858.CD002744.pub2.Further information for this Cochrane review is available in this issue of EBCH in the accompanying Commentary and EBCH Summary articles. Copyright © 2008 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd. The Cochrane Collaboration
Commentary on ‘Neuraminidase inhibitors for preventing and treating influenza in children’
Authors: Barton Michelle A. , Allen Upton D. 
Published: June 2008

AbstractThis is a commentary on a Cochrane review, published in this issue of EBCH, first published as: Matheson NJ, Harnden AR, Perera R, Sheikh A, Symmonds‐Abrahams M. Neuraminidase inhibitors for preventing and treating influenza in children. Cochrane Database of Systematic Reviews 2007, Issue 1. Art. No.: CD002744. DOI: 10.1002/14651858.CD002744.pub2.Further information for this Cochrane review is available in this issue of EBCH in the accompanying EBCH Summary and Characteristics and Key Findings Tables. Copyright © 2008 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd. The Cochrane Collaboration
Summary of ‘Psychological interventions for needle‐related procedural pain and distress in children and adolescents’
Authors: Milne Andrea 
Published: June 2008

AbstractThis is a summary of a Cochrane review, published in this issue of EBCH, first published as: Uman LS, Chambers CT, McGrath PJ, Kisely S. Psychological interventions for needle‐related procedural pain and distress in children and adolescents. Cochrane Database of Systematic Reviews 2006, Issue 4. Art. No.: CD005179. DOI: 10.1002/14651858.CD005179.pub2.Further information for this Cochrane review is available in this issue of EBCH in the accompanying Commentary and Characteristics and Key Findings Tables articles. Copyright © 2008 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd. The Cochrane Collaboration
Summary of ‘Corticosteroids for acute bacterial meningitis’
Authors: Milne Andrea 
Published: June 2008

AbstractThis is a summary of a Cochrane review, published in this issue of EBCH, first published as: van de Beek D, de Gans J, McIntyre P, Prasad K. Corticosteroids for acute bacterial meningitis. Cochrane Database of Systematic Reviews 2007, Issue 1. Art. No.: CD004405. DOI: 10.1002/14651858.CD004405.pub2.Further information for this Cochrane review is available in this issue of EBCH in the accompanying Commentary and Characteristics and Key Findings Tables articles. Copyright © 2008 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd. The Cochrane Collaboration
Summary of ‘Recombinant growth hormone for idiopathic short stature in children and adolescents’
Authors: Milne Andrea 
Published: June 2008

AbstractThis is a summary of a Cochrane review, published in this issue of EBCH, first published as: Bryant J, Baxter L, Cave CB, Milne R. Recombinant growth hormone for idiopathic short stature in children and adolescents. Cochrane Database of Systematic Reviews 2007, Issue 3. Art. No.: CD004440. DOI: 10.1002/14651858. CD004440.pub2Further information for this Cochrane review is available in this issue of EBCH in the accompanying Commentary and Characteristics and Key Findings Tables articles. Copyright © 2008 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd. The Cochrane Collaboration
Characteristics and key findings for ‘Recombinant growth hormone for idiopathic short stature in children and adolescents’
Authors: van Dalen E. C. , Offringa M. 
Published: June 2008

AbstractThese are the characteristics and key findings for a Cochrane review published in this issue of EBCH, first published as: Bryant J, Baxter L, Cave CB, Milne R. Recombinant growth hormone for idiopathic short stature in children and adolescents. Cochrane Database of Systematic Reviews 2007, Issue 3. Art.No.:CD004440. DOI:10.1002/14651858.CD004440.pub2.Further information for this Cochrane review is available in this issue of EBCH in the accompanying EBCH Summary and Commentary articles. Copyright © 2008 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd. The Cochrane Collaboration
Summary of ‘Nasal saline irrigations for the symptoms of chronic rhinosinusitis’
Authors: Milne Andrea 
Published: June 2008

AbstractThis is a summary of a Cochrane review, published in this issue of EBCH, first published as: Harvey R, Hannan SA, Badia L, Scadding G. Nasal saline irrigations for the symptoms of chronic rhinosinusitis. Cochrane Database of Systematic Reviews 2007, Issue 3. Art. No.: CD006394. DOI: 10.1002/14651858. CD006394.pub2.Further information for this Cochrane review is available in this issue of EBCH in the accompanying EBCH Commentary and Characteristics and Key Findings Tables articles. Copyright © 2008 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd. The Cochrane Collaboration