bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Relationship Between Cognition of Lying and the Previous Day's Lies
Authors: Tabata Naoya 
Published: March 2024

AbstractThe research on the Cognition of Lying Scale, assessing how people think about lying in general, has demonstrated a negative correlation between the cognition of negative aspects of lying score and the number of lies told the previous day. This study reexamined the relationship between the cognition of lying and the number of lies told the previous day after controlling for socially desirable responses. Japanese university students (N = 105) responded to the Cognition of Lying Scale and scales assessing socially desirable responses. The study evaluated the lies told the previous day using the Day Reconstruction Method, in which participants described the previous day's events and details of the lies they told. Two coders classified the lies as self‐oriented or other‐oriented. The results were consistent with the previous study and indicated that the cognition of negative aspects of lying was significantly and negatively related to the total number of lies, both self‐oriented and other‐oriented, after controlling for socially desirable responses.
A critical review of soil algae as a crucial soil biological component of high ecological and economic significance
Authors: Joseph Jebin , Ray Joseph George 
Published: March 2024

AbstractAero‐terrestrial algae are ecologically and economically valuable bioresources contributing to carbon sequestration, sustenance of soil health, and fertility. Compared to aquatic algae, the literature on subaerial algae is minimal, including studies of distinctive habitats such as forest soils, agricultural fields, deserts, polar regions, specific subaerial zones, artificial structures, and tropical soils. The primary goal here was to identify the gaps and scope of research on such algae. Accordingly, the literature was analyzed per sub‐themes, such as the “nature of current research data on terrestrial algae,” “methodological approaches,” “diversity,” “environmental relationships,” “ecological roles,” and “economic significance.” The review showed there is a high diversity of algae in soils, especially members belonging to the Cyanophyta (Cyanobacteria) and Chlorophyta. Algal distributions in terrestrial environments depend on the microhabitat conditions, and many species of soil algae are sensitive to specific soil conditions. The ecological significance of soil algae includes primary production, the release of biochemical stimulants and plant growth promoters into soils, nitrogen fixation, solubilization of minerals, and the enhancement and maintenance of soil fertility. Since aero‐terrestrial habitats are generally stressed environments, algae of such environments can be rich in rare metabolites and natural products. For example, epilithic soil algae use wet adhesive molecules to fix them firmly on the substratum. Exploring the ecological roles and economic utility of soil and other subaerial algae could be helpful for the development of algae‐based industries and for achieving sustainable soil management.
Periodontal tissue regeneration with cementogenesis after application of brain‐derived neurotrophic factor in 3‐wall inflamed intra‐bony defect
Authors: Kiyota Mari , Iwata Tomoyuki , Hasegawa Naohiko , Sasaki Shinya , Taniguchi Yuri , Hamamoto Yuta , Matsuda Shinji , Ouhara Kazuhisa , Takeda Katsuhiro , Fujita Tsuyoshi , Kurihara Hidemi , Kawaguchi Hiroyuki , Mizuno Noriyoshi 
Published: March 2024

AbstractObjectiveThe purpose of this study is to investigate regenerative process by immunohistochemical analysis and evaluate periodontal tissue regeneration following a topical application of BDNF to inflamed 3‐wall intra‐bony defects.BackgroundBrain‐derived neurotrophic factor (BDNF) plays a role in the survival and differentiation of central and peripheral neurons. BDNF can regulate the functions of non‐neural cells, osteoblasts, periodontal ligament cells, endothelial cells, as well as neural cells. Our previous study showed that a topical application of BDNF enhances periodontal tissue regeneration in experimental periodontal defects of dog and that BDNF stimulates the expression of bone (cementum)‐related proteins and proliferation of human periodontal ligament cells.MethodsSix weeks after extraction of mandibular first and third premolars, 3‐wall intra‐bony defects were created in mandibular second and fourth premolars of beagle dogs. Impression material was placed in all of the artificial defects to induce inflammation. Two weeks after the first operation, BDNF (25 and 50 μg/mL) immersed into atelocollagen sponge was applied to the defects. As a control, only atelocollagen sponge immersed in saline was applied. Two and four weeks after the BDNF application, morphometric analysis was performed. Localizations of osteopontin (OPN) and proliferating cell nuclear antigen (PCNA)‐positive cells were evaluated by immunohistochemical analysis.ResultsTwo weeks after application of BDNF, periodontal tissue was partially regenerated. Immunohistochemical analyses revealed that cells on the denuded root surface were positive with OPN and PCNA. PCNA‐positive cells were also detected in the soft connective tissue of regenerating periodontal tissue. Four weeks after application of BDNF, the periodontal defects were regenerated with cementum, periodontal ligament, and alveolar bone. Along the root surface, abundant OPN‐positive cells were observed. Morphometric analyses revealed that percentage of new cementum length and percentage of new bone area of experimental groups were higher than control group and dose‐dependently increased.ConclusionThese findings suggest that BDNF could induce cementum regeneration in early regenerative phase by stimulating proliferation of periodontal ligament cells and differentiation into periodontal tissue cells, resulting in enhancement of periodontal tissue regeneration in inflamed 3‐wall intra‐bony defects.
BBR affects macrophage polarization via inhibition of NF‐κB pathway to protect against T2DM‐associated periodontitis
Authors: Xia Siying , Jing Rui , Shi Mingyan , Yang Yanan , Feng Meiting , Deng Li , Luo Lijun 
Published: March 2024

AbstractBackground and ObjectivePeriodontitis is intimately associated with the development of various systemic diseases, among which type 2 diabetes mellitus (T2DM) has a bidirectional relationship with the pathogenesis of periodontitis. The objective of the present work was to investigate the role of berberine (BBR) in periodontitis with T2DM and related mechanisms.MethodsThe mRNA expression of macrophage polarization‐related factors in the microenvironment of periodontal inflammation was detected using real‐time quantitative PCR (RT‐qPCR). The experimental periodontitis model was constructed in wild‐type (WT) and T2DM (db/db) mice, which were administered BBR after 7 days of modeling. Alveolar bone loss (ABL) in each group of mice was measured utilizing micro‐computed tomography images. RT‐qPCR was performed to analyze the levels of macrophage polarization‐related factors in mouse gingiva. Lastly, using western blotting and RT‐qPCR, the signaling pathway of BBR affecting macrophage polarization in the microenvironment of periodontitis was explored.ResultsBBR inhibited M1 polarization and stimulated M2 polarization in the periodontitis microenvironment. BBR decreased ABL in the WT and T2DM periodontitis models. And BBR reduced the production of proinflammatory cytokines and increased anti‐inflammatory cytokine expression in the gingiva of WT and T2DM model mice. Ultimately, BBR mediates its anti‐inflammatory effects on periodontitis through inhibition of the NF‐κB pathway.ConclusionsBBR had a therapeutic effect on T2DM‐associated periodontitis via inhibiting the NF‐κB pathway to affect macrophage polarization, which may have implications for the new pharmacological treatment of T2DM‐associated periodontitis.
FOXO1 regulates wound‐healing responses in human gingival fibroblasts
Authors: Rojas Leticia , Tobar Nicolás , Espinoza Javier , Ríos Susana , Martínez Constanza , Martínez Jorge , Graves Dana T. , Smith Patricio C. 
Published: March 2024

AbstractBackground and objectiveForkhead box‐O 1 (FOXO1) is a transcription factor actively involved in oral wound healing at the epithelial barrier. However, less is known regarding the role of FOXO1 during the tissue repair response in the connective tissue compartment. This study explored the involvement of FOXO1 in the modulation of fibroblast activity related to wound healing.MethodsPrimary cultures of human gingival fibroblasts were obtained from four healthy young donors. Myofibroblastic differentiation, collagen gel contraction, cell migration, cell spreading, and integrin activation were evaluated in the presence or absence of a FOXO1 inhibitor (AS1842856). Variations in mRNA and proteins of interest were evaluated through qRT‐PCR and western blot, respectively. Distribution of actin, α‐smooth muscle actin, and β1 integrin was evaluated using immunofluorescence. FOXO1 and TGF‐β1 expression in gingival wound healing was assessed by immunohistochemistry in gingival wounds performed in C57BL/6 mice. Images were analyzed using ImageJ/Fiji. ANOVA or Kruskal‐Wallis test followed by Tukey's or Dunn's post‐hoc test was performed. All data are expressed as mean ± SD. p < .05 was considered statistically significant.ResultsFOXO1 inhibition caused a decrease in the expression of the myofibroblastic marker α‐SMA along with a reduction in fibronectin, type I collagen, TGF‐β1, and β1 integrin mRNA level. The FOXO1 inhibitor also caused decreases in cell migration, cell spreading, collagen gel contraction, and β1 integrin activation. FOXO1 and TGF‐β1 were prominently expressed in gingival wounds in fibroblastic cells located at the wound bed.ConclusionThe present study indicates that FOXO1 plays an important role in the modulation of several wound‐healing functions in gingival fibroblast. Moreover, our findings reveal an important regulatory role for FOXO1 on the differentiation of gingival myofibroblasts, the regulation of cell migration, and collagen contraction, all these functions being critical during tissue repair and fibrosis.
The obligatoriness of arguments
Authors: Van Luven Katie , Toivonen Ida 
Published: March 2024

AbstractA common diagnostic for distinguishing between arguments and adjuncts is obligatoriness/optionality: as a rule of thumb, arguments are obligatory and adjuncts are optional. However, there are many examples of optional arguments, which have led researchers to question the usefulness of this diagnostic and sometimes even the very distinction between arguments and adjuncts. This paper aims to show that arguments are not simply optional; they are omissible only under identifiable grammatical and pragmatic conditions. By contrast, there are no conditions on when adjuncts can be omitted. There are instead pragmatic conditions that dictate the inclusion of adjuncts.
Characterizing anthropogenic litter pollutants in African freshwater ecosystems: A case study of Dunga Beach in Lake Victoria, Kenya
Authors: Ogello Erick O. , Mbodze Mwaruwa M. , Outa Nicholas O. , Ajode Migeni Z. , Ojwando Wycliffe 
Published: March 2024

AbstractAnthropogenic litter (AL) in world's aquatic ecosystems presents critical ecological threats to environmental quality, aquatic biodiversity and human welfare. However, most studies on AL have been conducted in marine ecosystems with very little focus being given to freshwater systems like Lake Victoria. This study characterized AL pollutants in Dunga beach in Lake Victoria, Kenya, where sampling was done in the beach, riparian and benthic zones along a 100 m reach for 6 days. Across the sampled reaches, the AL associated with packaging, consumer products, building and construction, transport, electronic wastes, textile, fishery and medical materials were collected, counted, sun‐dried and weighed. AL were more abundant in the beach and riparian zone than in the benthic reaches with plastics being the dominant litter in all reaches. Based on Kruskal–Wallis rank sum test the density of AL associated with packaging and consumer products was significantly higher than other AL in all the reaches. Plastics, polystyrene and glass wastes dominated the beach zone at 31.19%, 12.14% and 11.14%, respectively. In the benthic area, the dominant wastes were plastics, fishery and polystyrene items at 22.14%, 16.34% and 12.14%, respectively. The top 10 AL pollutants in Dunga beach were as follows: bags/food wrappers, bottle caps, diapers, plastic and glass beverage bottles, plastic plates, forks, knives, spoons, straws and e‐wastes. Based on data from literature, several clear patterns emerged when comparing relative AL abundance across other aquatic habitats. In the Lake Michigan Beach, the AL were dominated by plastics (41.2%) followed by cigarettes at 29.3%. In contrast, Chicago River Beach contained more glass wastes (42.1%) while Chicago River Riparian had more plastics (57.8%). At the South Sea of Korea, fishing gear wastes were the majority AL (61.1%). AL consisting of fishing items was restricted to benthic and riparian settings, in which the benthic zone had the most items recorded. It is therefore evident that a large amount of AL waste accumulates at Dunga, Hippo point and other beaches in the world, thus justifying the need for beach cleaning and maintenance strategies. This study presents baseline data that is useful to environmental ecologists, aquatic scientists and management authorities to formulate policies, evaluate guidelines and recommend beach management strategies to conserve aquatic biodiversity, human health and aesthetic value of the freshwater habitats.
Response of Mediterranean Sea bivalves to Pliocene–Pleistocene environmental changes
Authors: Mondanaro Alessandro , Dominici Stefano , Danise Silvia 
Published: March 2024

AbstractThe Mediterranean Sea is recognized as a hotspot of marine biodiversity. Analysing its past biodiversity can help in understanding species' response to climate change. We built a species‐level dataset of bivalve occurrences across the Zanclean–Calabrian interval, a time characterized by significant changes in climate, and by bivalve extinctions. The dataset includes more than 400 species distributed from the eastern to the western Mediterranean Sea. We measured changes in richness and turnover through time, for the entire dataset, and for different palaeoenvironments and combinations of tiering and feeding categories to test if specific environmental conditions and different lifestyles were correlated to species extinction or survival through time. We also compared niche breadth, geographical range size, and species abundance of extinct and extant species, to test which of these parameters potentially affected extinction risk. Our results confirm a loss of biodiversity between 3 Ma and the Early Pleistocene, although this loss was less intense and more gradual than previously estimated. We also found significant differences in niche breadth and geographical range size between extinct and extant species. Suspension feeders lost a higher proportion of species and suffered a higher reduction of geographical range compared to infaunal deposit feeders. Species loss was more protracted and higher on the shoreface than on the shelf, which is probably related to the reduction of shallow‐water vegetated environments and to the disaggregation of heterozoan carbonate ramp habitats with cooling and sea‐level drop at the onset of the northern hemisphere glaciation.
Melanoma‐like features in pediatric longitudinal melanonychia: A systematic review and meta‐analysis
Authors: Tsai Serena Yun‐Chen , Hamilton Claire E. , Mologousis Mia A. , Hawryluk Elena B. 
Published: March 2024

AbstractBackgroundPediatric longitudinal melanonychia (LM) can exhibit atypical features that mimic red‐flag signs for subungual melanoma in adults and lead to diagnostic uncertainty. Nail biopsy may be unnecessary if clinical inspection and dermoscopy suggest a benign nature.MethodsWe searched PubMed and Embase from inception to February 2023 for studies of any design reporting either the number or proportion of clinical and dermoscopic features in at least five children (≤18 years) with LM. Non‐English articles, reviews, and abstracts were excluded. We performed a systematic review and meta‐analysis to collate all existing data.ResultsA total of 1218 articles were screened and 24 studies with 1391 pediatric patients were included. Nevus was the most common diagnosis (86.3%). The most prevalent sites were fingernails (76.2%) and first digits (45.4%). Pooled proportions of common features were: dark‐color bands (69.8%), multi‐colored bands (47.6%), broad bandwidth (41.1%), pseudo‐Hutchinson sign (41.0%), irregular patterns (38.1%), Hutchinson sign (23.7%), dots and globules (22.5%), nail dystrophy (18.2%), and triangular sign (10.9%). Outcomes included progression (widening or darkening, 29.9%), stability (23.3%), and spontaneous regression (narrowing or fading, 19.9%). Only eight cases of subungual melanoma in situ were reported, and no invasive melanomas were identified.ConclusionAlthough atypical characteristics are common in pediatric LM, the probability of malignant transformation is exceedingly low. Appropriate evaluation and management of pediatric LM includes careful clinical and dermoscopic inspection with attention to benign features followed by long‐term interval follow‐up.
The Wells–Riley model revisited: Randomness, heterogeneity, and transient behaviours
Authors: Edwards Alexander J. , King Marco‐Felipe , Noakes Catherine J. , Peckham Daniel , López‐García Martín 
Published: March 2024

AbstractThe Wells–Riley model has been widely used to estimate airborne infection risk, typically from a deterministic point of view (i.e., focusing on the average number of infections) or in terms of a per capita probability of infection. Some of its main limitations relate to considering well‐mixed air, steady‐state concentration of pathogen in the air, a particular amount of time for the indoor interaction, and that all individuals are homogeneous and behave equally. Here, we revisit the Wells–Riley model, providing a mathematical formalism for its stochastic version, where the number of infected individuals follows a Binomial distribution. Then, we extend the Wells–Riley methodology to consider transient behaviours, randomness, and population heterogeneity. In particular, we provide analytical solutions for the number of infections and the per capita probability of infection when: (i) susceptible individuals remain in the room after the infector leaves, (ii) the duration of the indoor interaction is random/unknown, and (iii) infectors have heterogeneous quanta production rates (or the quanta production rate of the infector is random/unknown). We illustrate the applicability of our new formulations through two case studies: infection risk due to an infectious healthcare worker (HCW) visiting a patient, and exposure during lunch for uncertain meal times in different dining settings. Our results highlight that infection risk to a susceptible who remains in the space after the infector leaves can be nonnegligible, and highlight the importance of incorporating uncertainty in the duration of the indoor interaction and the infectivity of the infector when estimating risk.
Variations of skin thermal diffusivity on different skin regions
Authors: Bajrami Dardan , Zubiaga Asier , Renggli Timon , Kirsch Christoph , Spano Fabrizio , Fehr Daniel , von Schulthess Patrick , Lindhorst‐Peters Alisa , Huber Stephanie , Roider Elisabeth , Rossi René M. , Navarini Alexander A. , Bonmarin Mathias 
Published: March 2024

AbstractBackground and ObjectiveSkin thermal diffusivity plays a crucial role in various applications, including laser therapy and cryogenic skin cooling.This study investigates the correlation between skin thermal diffusivity and two important skin parameters, melanin content and erythema, in a cohort of 102 participants.MethodsAn in‐house developed device based on transient temperature measurement was used to assess thermal diffusivity at different body locations. Melanin content and erythema were measured using a colorimeter. Statistical analysis was performed to examine potential correlations.ResultsThe results showed that the measured thermal diffusivity values were consistent with previous reports, with variations observed among subjects. No significant correlation was found between thermal diffusivity and melanin content or erythema. This suggests that other factors, such as skin hydration or epidermis thickness, may have a more dominant influence on skin thermal properties.ConlcusionThis research provides valuable insights into the complex interplay between skin thermal properties and physiological parameters, with potential implications for cosmetic and clinical dermatology applications.
Emergence of novel circoviruses in humans and pigs and their possible importance for xenotransplantation and blood transfusions
Authors: Opriessnig Tanja , Xiao Chao‐Ting , Mueller Nicolas J. , Denner Joachim 
Published: March 2024

AbstractBackgroundAs sequencing is becoming more broadly available, virus discovery continues. Small DNA viruses contribute to up to 60% of the overall virus load in pigs. Porcine circoviruses (PCVs) are small DNA viruses with a single‐stranded circular genome. They are common in pig breeds and have not been properly addressed for their potential risk in xenotransplantation. Whereas PCV1 is non‐pathogenic in pigs, PCV2 has been associated with various disease manifestations. Recently two new circoviruses have been described, PCV3 and PCV4. While PCV4 is currently present mainly in Asia, PCV3 is widely distributed, and has been identified in commercial pigs, wild boars, and pigs generated for xenotransplantation. In one case PCV3 was transmitted by pigs to baboons via heart transplantation. PCV3 pathogenicity in pigs was controversial initially, however, the virus was found to be associated with porcine dermatitis and nephropathy syndrome (PDNS), reproductive failure, and multisystemic inflammation. Inoculation studies with PCV3 infectious clones confirmed that PCV3 is pathogenic. Most importantly, recently discovered human circoviruses (CV) are closely related to PCV3.MethodsLiterature was evaluated and summarized. A dendrogram of existing circoviruses in pigs, humans, and other animal species was created and assessed at the species level.ResultsWe found that human circoviruses can be divided into three species, human CV1, CV2, and CV3. Human CV2 and CV3 are closest to PCV3.ConclusionsCircoviruses are ubiquitous. This communication should create awareness of PCV3 and the newly discovered human circoviruses, which may be a problem for blood transfusions and xenotransplantation in immune suppressed individuals.