bluuebunny/crossref_metadata_2025_split huggingface dataset:
Performance of T2-based PCA mix control chart with KDE control limit for monitoring variable and attribute characteristics
Authors: Ahsan Muhammad , Mashuri Muhammad , Prastyo Dedy Dwi , Lee Muhammad Hisyam 
Published: March 2024

AbstractIn this work, the mixed multivariate T2 control chart’s detailed performance evaluation based on PCA mix is explored. The control limit of the proposed control chart is calculated using the kernel density approach. Through simulation studies, the proposed chart’s performance is assessed in terms of its capacity to identify outliers and process shifts. When 30% more outliers are included in the data, the proposed chart provides a consistent accuracy rate for identifying mixed outliers. For the balanced percentage of attribute qualities, misdetection happens because of the high false alarm rate. For unbalanced attribute qualities and excessive proportions, the masking effect is the key issue. The proposed chart shows the improved performance for the shift in identifying the shift in the process.
Effect of sulfasalazine on ferroptosis during intestinal injury in rats after liver transplantation
Authors: Wu Wei , Bu Wenhao , Tan Yongxing , Wang Yongwang 
Published: March 2024

AbstractUsing a rat autologous orthotopic liver transplantation (AOLT) model and liver cold ischemia–reperfusion (I/R)-induced intestinal injury, we clarified whether ferroptosis occurred in rat AOLT cold I/R-induced intestinal injury. Additionally, the role and possible mechanism of the ferroptosis activator sulfasalazine (SAS) in intestinal injury-induced ferroptosis in rats with AOLT liver cold I/R were investigated. Sixty specific pathogen free (SPF)-grade adult male Sprague‒Dawley (SD) rats were randomly divided into 5 groups using the random number table method (n = 12). Six rats were randomly selected at 6 hour (h) and 24 h after I/R. Inferior vena cava blood specimens were collected from the portal vein (PV) opening at 6 h and 24 h. The concentrations of serum malondialdehyde (MDA), serum interleukin 6 (IL-6) were determined by enzyme-linked immunosorbent assay (ELISA). Ileal tissue was obtained from the PV opening in rats in each group at 6 h and 24 h, and ileal tissue sections were observed under light microscopy. The contents of intestinal MDA, superoxide dismutase (SOD), glutathione(GSH), glutathione peroxidase 4 (GPX4), and tissue iron were determined by ELISA, and the expression of GPX4 and the cysteine glutamate reverse transporter light chain protein (xCT) was determined by Western blot. The experimental results show that ferroptosis is involved in the pathophysiological process of intestinal injury induced by cold hepatic ischemia–reperfusion in AOLT rats. In addition, SAS (500 mg/kg) may inhibit the cystine/glutamate antiporters (System Xc¯)/GSH/GPX4 signal axis in intestinal injury induced by cold I/R in rat AOLT liver, or iron overload after reperfusion, causing a massive accumulation of L-ROS and activating cellular ferroptosis, further aggravate the intestinal injury.
Social entrepreneurial intention among university students in China
Authors: Lyu Xinyue , Al Mamun Abdullah , Yang Qing , Aziz Norzalita Abd 
Published: March 2024

AbstractThe issues of employment, social inequality, and resource scarcity can be effectively addressed through social entrepreneurship, contributing to the growing research interest on the formation of social entrepreneurial intention. Using the theory of planned behaviour, the current study examined the influence of selected key factors on social entrepreneurial intention among university students. Based on the cross-sectional quantitative research design, online survey was conducted, which involved 684 students and graduates from five universities in Southern China. The obtained results demonstrated the significant and positive influence of perceived values on sustainability, opportunity recognition competency, attitude towards entrepreneurship, subjective norms, and perceived behavioural control on social entrepreneurial intention. Additionally, attitude towards entrepreneurship partially mediated the relationships of risk-taking propensity, self-efficacy, and need for achievement on social entrepreneurial intention. The multi-group analysis results also showed that need for achievement and social entrepreneurial intention differed significantly between genders, which provides new ideas for future investigations into the impact of gender on social entrepreneurial intentions. Based on the findings of this study, it is crucial that university students are exposed to relevant courses or training to develop social entrepreneurship competencies and promote sustainable values. The findings of this study will provide policymakers with relevant policy guidelines and more effective theoretical support to achieve the goal of promoting social entrepreneurship among university students in a more resource-efficient and effective manner.
Green synthesis of chitosan nanoparticles using tea extract and its antimicrobial activity against economically important phytopathogens of rice
Authors: Sathiyabama M. , Boomija R. V. , Muthukumar S. , Gandhi M. , Salma S. , Prinsha T. Kokila , Rengasamy B. 
Published: March 2024

AbstractThe aim of the present work is to biosynthesize Chitosan nanoparticles (CTNp) using tea (Camellia sinensis) extract, with potent antimicrobial properties towards phytopathogens of rice. Preliminary chemical analysis of the extract showed that they contain carbohydrate as major compound and uronic acid indicating the nature of acidic polysaccharide. The structure of the isolated polysaccharide was analyzed through FTIR and 1H NMR. The CTNp was prepared by the addition of isolated tea polysaccharides to chitosan solution. The structure and size of the CTNp was determined through FTIR and DLS analyses. The surface morphology and size of the CTNp was analysed by SEM and HRTEM. The crystalinity nature of the synthesized nanoparticle was identified by XRD analysis. The CTNp exhibited the antimicrobial properties against the most devastating pathogens of rice viz., Pyricularia grisea, Xanthomonas oryzae under in vitro condition. CTNp also suppressed the blast and blight disease of rice under the detached leaf assay. These results suggest that the biosynthesized CTNp can be used to control the most devastating pathogens of rice.
Prescribing cascades of antigout medications from thiazide diuretics in gout-naïve hypertensive adults receiving first-line pharmacological management
Authors: Lu Shang-Yeh , Hsu Hsing-Yu , Hsieh Yow-Wen , Lu Chiung-Ray , Huang Hsin-Yi , Chang Shih-Sheng 
Published: March 2024

AbstractPrescribing cascade is a significant clinical problem but is often overlooked. We explore the incidence of the prescribing cascades of antigout medications related to thiazide treatment in gout-naïve hypertensive adults newly exposed to the pharmacological treatment. This population-based, retrospective cohort study used the Taiwan National Health Insurance Registry Database. Gout-naïve hypertensive adults who were newly dispensed first-line antihypertensive drugs between January 1, 2000, and December 31, 2016, were enrolled. Patients were divided into the thiazide group (n = 4192) and the non-thiazide group (n = 81,083). The non-thiazide group included patients who received an angiotensin-converting enzyme inhibitor, angiotensin II receptor blocker, calcium channel blocker, or beta-blocker. The study utilized propensity score matching and multivariable Cox regression models to investigate the prescribing cascade of antigout agents following antihypertensive treatment, adjusting for factors like age, sex, comorbidities, and concurrent medications. After propensity score matching, each group consisted of 4045 patients, with the thiazide group exhibiting a higher risk of being prescribed antigout medications across different time intervals post-treatment initiation. Specifically, adjusted hazard ratios (aHRs) for the thiazide group were 2.23, 2.07, and 2.41 for < 30 days, 31–180 days, and > 180 days, respectively, indicating a sustained and significant risk over time. Comparative analyses revealed thiazide diuretics were associated with a higher risk of antigout medication prescriptions compared to other antihypertensive classes, particularly evident after 180 days. Subgroup analyses across various demographics and comorbidities consistently showed an increased risk in the thiazide cohort. Gout-naïve hypertensive adults newly dispensed thiazide had a higher risk of subsequently adding antigout agents than those taking other first-line antihypertensive medications. The awareness and interruption of these prescribing cascades are critical to improving patient safety.
Local tuning of Rydberg exciton energies in nanofabricated Cu2O pillars
Authors: Paul Anindya Sundar , Rajendran Sai Kiran , Ziemkiewicz David , Volz Thomas , Ohadi Hamid 
Published: March 2024

AbstractRydberg excitons in Cu2O feature giant optical nonlinearities. To exploit these nonlinearities for quantum applications, the confinement must match the Rydberg blockade size, which in Cu2O could be as large as a few microns. Here, in a top-down approach, we show how exciton confinement can be realised by focused-ion-beam etching of a polished bulk Cu2O crystal without noticeable degradation of the excitonic properties. The etching of the crystal to micron sizes allows for tuning the energies of Rydberg excitons locally, and precisely, by optically induced temperature change. These results pave the way for exploiting the large nonlinearities of Rydberg excitons in micropillars for making non-classical light sources, while the precise tuning of their emission energy opens up a viable pathway for realising a scalable photonic quantum simulation platform.
Synthesis and Biological Activity of Penaresidins A and B, Penazetidine A, and Related Analogues
Authors: Burns Sean M. , McClure Timothy J. , Parikh Seren G. , Schindler Corinna S. 
Published: March 2024

AbstractSince the first reports of their isolation, penaresidins A and B together with penazetidine A and related analogues have attracted interest from the synthetic community for their unique structural features, specifically the highly functionalized azetidine core. This review provides a comprehensive overview of the biological activity of the penaresidins, penazetidine, and their analogues together with reported synthetic strategies developed since their isolation.1	Introduction2	Biological Activity of Penaresidin A, Penaresidin B, and Penazetidine A and Related Analogues3	Retrosynthetic Analysis4	Penaresidin A Analogue (Kamikawa, 1995)5	15-epi-Penaresidin A (Mori, 1995)6	16-epi-Penazetidine A (Mori, 1996)7	Penaresidin B (Yoda, 1997)8	15-epi-Penaresidin B and Penaresidin B (Mori, 1997)9	Penaresidin A and 16-nor-Penazetidine A (Knapp, 1997)10	Substituted Penaresidin Core (Beauhaire and Ducrot, 1998)11	Substituted Penaresidin Core (Ducrot, 1999)12	Penaresidin A (Lin, 1999)13	Penaresidin B (Yoda, 2003)14	Penaresidin Structure-Reactivity Relationship (Kobayashi, 2007)15	Penaresidin A (Raghavan, 2010)16	Penaresidin A (Reddy, 2014)17	Penaresidin B (Liu, 2015)18	Penaresidin B (Yakura, 2018)19	Penaresidin B (DuBois, 2020)20	Penaresidin Analogues (Bodnár, 2021)
Standardizing the Treatment for Pediatric Status Epilepticus: A Quality Improvement Study
Authors: Bhargava Rishi , Cobo Nicole , Smith Gabrielle , Hestekin Heather , Morphew Tricia , Babbitt Christopher 
Published: March 2024

AbstractApproximately 30 to 40% of children with generalized convulsive status epilepticus remain refractory to benzodiazepines. Due to inconsistences in our approach for these patients in the emergency department, we initiated a quality improvement project to standardize the treatment process.A plan, do, study, act (PDSA) format was used for the project that involved creating a treatment algorithm based on the American Epilepsy Society (AES) guidelines, educating the staff on the treatment recommendations, and then collecting clinical data. We selected time to second-line anticonvulsant therapy as our primary outcome measure. Following the implementation of the treatment algorithm and order set, we performed comparative analyses of the pre- and post-implementation cohorts.A total of 21 pre- and 36 post-implementation patients were identified. Baseline data demonstrated no difference in age or gender. Post-implementation patients received second-line therapy sooner (24 vs. 39 minutes, p = 0.001) and more post patients received second-line therapy within the AES guideline's time frame (83 vs. 52%, p = 0.012) compared with the pre-implementation patients. In a multivariable analysis, post-implementation patients had a higher likelihood of receiving second-line therapy within the AES-recommended time frame (odds ratio [OR] = 5.78; 95% confidence interval [CI]: 1.49–22.48; p = 0.011). Age, gender, intubation status, anticonvulsants given prior to emergency department (ED), and treatment by a pediatric ED specialist were not associated with increased odds of provider adherence to AES guidelines.In conclusion, a standardized approach utilizing a treatment algorithm for patients with pediatric benzodiazepine refractory status epilepticus was associated with reduced time to administration of second-line anticonvulsant therapy and better compliance with AES guidelines in a mixed pediatric and adult ED setting.
Dual circular complementary split ring resonator based metamaterial sensor with high sensitivity and quality factor for textile material detection
Authors: Alsaif Haitham , Islam Md. Rashedul , Hoque Ahasanul , Soliman Mohamed S. , Islam Md. Shabiul , Islam Mohammad Tariqul 
Published: March 2024

In this paper, a novel metamaterial sensor with excellent sensitivity and quality factor for microwave sensing applications is presented. The designed metamaterial sensor is assembled on a 1.575 mm thickness of low-cost dielectric substrate material (Rogers RT5880), and the copper is used as a resonator. Computer Simulation Technology version 2019 (CST-2019) software is employed to design and analyze the proposed metamaterial sensor. In addition, the Advanced Design System version 2016 (ADS 2016) software is used to validate the CST simulated model. Subsequently, the simulated results were validated using laboratory measurements. The optimized cell is small; its dimension is 10 × 10 mm2, and the obtained resonances are 3.85 and 6.85 GHz with notches of −26.29 and −40.03 dB, respectively. The textile material is detected by the resonance frequency change, and this frequency is dependent on the material’s permittivity values. To test the developed sensor’s sensing capabilities, three types of textiles—wool, fleece, and denim—are used. The effective medium ratio, sensitivity, and Q-factor of the structure are evaluated, and the obtained values are 8.96, 14.57%, and 345, respectively. The sensor for detecting textile materials works in the S and C bands. The resonances are shifted 530 MHz between the air and wool, 420 MHz between the air and fleece, and 640 MHz between the air and denim. The simulated outcomes and laboratory results almost matched. The projected sensor can be employed in the apparel sector to identify textile materials because it is small, inexpensive, has a high quality factor, and has high sensitivity.
Redesigning the soil Tea Bag Index methodology for school and citizen science in Australia
Authors: Ng Wartini , McBratney Alex B. , Pino Vanessa , O’Brien Eugenia , Baumeister Bendrik 
Published: March 2024

Context The Tea Bag Index (TBI) evaluates the rate of organic matter decomposition using Lipton tea bags. However, this tea bag cannot be easily found in Australia, having to be imported from Europe. The 90-day incubation period also poses problems for school and citizen science projects, such as missing tea bags and organism-induced damage. Aims The study aims to: (1) investigate the suitable alternative Australian tea bag brands for the decomposition studies; (2) assess the potential for reducing the incubation period; and (3) evaluate the priming effects of different substrates on decomposition rate. Methods The feasibility of two local Australian tea bag brands (Madame Flavour or T2) was compared to Lipton by collecting time-series data over the incubation period in pot experiments with the addition of sugar, citric acid and microplastic. Key results We found an alternative tea brand that can be used for TBI in Australia. Conclusions (1) Madame Flavour tea bags can be used as an alternative litter material for the TBI in Australia. (2) The incubation period potentially could be reduced to 21 days, with another sampling taken on day 4 and 14. (3) Although there is a significant difference in decomposition rate between the control and substrates addition, no significant difference in decomposition rate is found among different substrates. Implications The utilisation of the Madame Flavour tea bag enables the adoption of decomposition studies by a broader spectrum of citizen scientists in Australia.
A novel plating bath device for reducing surface copper thickness and improving wafer-scale uniformity
Authors: Zeng Guoxian , Zhang Chi , Niu Kai , Wang Fuliang , He Hu 
Published: March 2024

Abstract
Through silicon via (TSV) technology plays a pivotal role in three-dimensional integrated circuits. However, excessive surface thickness and uneven wafer plating during TSV copper electroplating pose significant challenges to TSV reliability. This paper proposes a novel rotating cathode electroplating technique that utilizes flow field induction by a rotating cathode to significantly reduce the surface copper thickness by approximately 8 μm, leading to improved uniformity of wafer-scale electroplating and facilitating rapid TSV filling. This study focuses on the impact of cathode rotation speed and chip position on TSV filling quality. The experimental findings demonstrate that increasing the cathode rotation speed reduces the diffusion layer thickness, thereby enhancing filling quality. Additionally, variations in chip position influence surface copper thickness. The introduction of bis(3-sulfopropyl) disulfide accelerant expedites the filling process, boosts the filling ratio, and enables defect-free TSV filling. This study offers valuable insights into the wafer-scale TSV electroplating process and facilitates the optimization of parameter settings during electroplating.
Shortcuts to adiabaticity: theoretical framework, relations between different methods, and versatile approximations
Authors: Hatomura Takuya 
Published: March 2024

Abstract
Shortcuts to adiabaticity guide given systems to final destinations of adiabatic control via fast tracks. Various methods have been proposed as shortcuts to adiabaticity. The basic theory of shortcuts to adiabaticity was established in the 2010s, but it has still been developing and many fundamental findings have been reported. In this topical review, we give a pedagogical introduction to the theory of shortcuts to adiabaticity and revisit relations between different methods. Some versatile approximations in counterdiabatic driving, which is one of the methods of shortcuts to adiabaticity, will be explained in detail. We also summarize the recent progress in studies of shortcuts to adiabaticity.
Crystal structure and magnetism of actinide oxides: a review
Authors: Rai Binod K , Bretaña Alex , Morrison Gregory , Greer Rosalie , Gofryk Krzysztof , zur Loye Hans-Conrad 
Published: March 2024

Abstract
In actinide systems, the 5f electrons experience a uniquely delicate balance of effects and interactions having similar energy scales, which are often difficult to properly disentangle. This interplay of factors such as the dual nature of 5f-states, strong electronic correlations, and strong spin–orbit coupling results in electronically unusual and intriguing behavior such as multi-k antiferromagnetic ordering, multipolar ordering, Mott-physics, mixed valence configurations, and more. Despite the inherent allure of their exotic properties, the exploratory science of even the more basic, binary systems like the actinide oxides has been limited due to their toxicity, radioactivity, and reactivity. In this article, we provide an overview of the available synthesis techniques for selected binary actinide oxides, including the actinide dioxides, sesquioxides, and a selection of higher oxides. For these oxides, we also review and evaluate the current state of knowledge of their crystal structures and magnetic properties. In many aspects, substantial knowledge gaps exist in the current body of research on actinide oxides related to understanding their electronic ground states. Bridging these gaps is vital for improving not only a fundamental understanding of these systems but also of future nuclear technologies. To this end, we note the experimental techniques and necessary future investigations which may aid in better elucidating the nature of these fascinating systems.
Atomic behavior of nickel-based single crystal superalloy during heat treatment process based on molecular dynamics
Authors: Zheng Min , Bian Zhiao , Chen Weihua , Sun Qichun , Chen Jie , Zhu Zongxiao 
Published: March 2024

Abstract
The heat treatment process plays a pivotal role in enhancing the characteristics of nickel-based single crystal (NBSC) superalloys. Nevertheless, there exists a paucity of comprehensive investigations concerning the microstructural evolution of NBSC superalloys during heat treatment. This study employs a molecular dynamics simulation method to control the temperature of the NBSC superalloy precisely, aiming to unveil intricate details regarding microstructural evolution, temperature distribution patterns, mechanical properties, and other pertinent aspects during the cooling phase. Additionally, a comparative analysis of internal defect evolution under varying cooling rates is undertaken. The findings highlight the consistently heightened activity of atoms in the γ phase compared to those in the γ′ phase. Notably, the stability disparity between these phases gradually diminishes as the temperature decreases during the cooling process. At elevated temperatures, the prevalence of amorphous phases and dislocations in the γ phase channel diminishes concomitantly with the temperature reduction. Strain distribution in the alloy primarily concentrates in the γ phase channel and the central cross position of the γ′ phase. The temperature reduction correlates with a decline in the alloy model’s strain. In the initial phase of strain reduction, stress fluctuation trends in the X, Y, and Z directions exhibit an initial increase followed by a gradual decrease. Furthermore, the atomic number of HCP defects and dislocation density exhibit distinct patterns of change contingent upon the cooling rates employed.