bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Holmberg effect of Luminous Red Galaxy (LRG) pairs of the SDSS Data Release 4 (SDSS4)
Authors: Deng X.‐F. , Zou S.‐Y. , He J.‐Z. , Jiang P. , He C.‐G. , Luo C.‐H. 
Published: February 2007

AbstractWe investigate the Holmberg effect of Luminous Red Galaxy (LRG) pairs of the SDSS Data Release 4 (SDSS4). It is found that the Holmberg effect of LRG pairs has no statistical significance. According to types of the two components in each pair, we divide the isolated LRG pair sample into three subsamples: the early+early subsample, the late+late subsample and the early+late subsample. Further analyses show that all LRG pair subsamples do not exhibit statistically significant Holmberg effect. (© 2007 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
Influence of calcium on microbial reduction of solid phase uranium(VI)
Authors: Liu Chongxuan , Jeon Byong‐Hun , Zachara John M. , Wang Zheming 
Published: February 2007

AbstractThe effect of calcium on the dissolution and microbial reduction of a representative solid phase uranyl [U(VI)], sodium boltwoodite (NaUO2SiO3OH · 1.5H2O), was investigated to evaluate the rate‐limiting step of microbial reduction of the solid phase U(VI). Microbial reduction experiments were performed in a culture of a dissimilatory metal‐reducing bacterium (DMRB), Shewanella oneidensis strain MR‐1, in a bicarbonate medium with lactate as electron donor at pH 6.8 buffered with PIPES. Calcium increased the rate of Na‐boltwoodite dissolution and U(VI) bioavailability by increasing its solubility through the formation of a ternary aqueous calcium‐uranyl‐carbonate species. The ternary species, however, decreased the rates of microbial reduction of aqueous U(VI). Laser‐induced fluorescence spectroscopy (LIFS) and transmission electron microscopy (TEM) collectively revealed that microbial reduction of solid phase U(VI) was a sequentially coupled process of Na‐boltwoodite dissolution, U(VI) aqueous speciation, and microbial reduction of dissolved U(VI) to U(IV) that accumulated on bacterial surfaces/periplasm. Under studied experimental conditions, the overall rate of microbial reduction of solid phase U(VI) was limited by U(VI) dissolution reactions in solutions without calcium and limited by microbial reduction in solutions with calcium. Generally, the overall rate of microbial reduction of solid phase U(VI) was determined by the coupling of solid phase U(VI) dissolution, U(VI) aqueous speciation, and microbial reduction of dissolved U(VI) that were all affected by calcium. Biotechnol. Bioneg. 2007;97: 1415–1422. © 2007 Wiley Periodicals, Inc.
Application of chromatographic theory for process characterization towards validation of an ion‐exchange operation
Authors: Kaltenbrunner O. , Giaverini O. , Woehle D. , Asenjo J.A. 
Published: February 2007

AbstractThe behavior of ion‐exchange chromatography is well understood with respect to changes in ionic strength, pH, resin ligand density, bed height, elution flow rate, and gradient slope. Their relative importance for any specific chromatographic situation varies. When a chromatographic operation utilized to purify a human therapeutic protein is prepared for validation before commercial production, numerous tests have to be performed to establish the relative importance of each operating parameter to define its future role and importance in the framework of in‐process controls. This prioritization process is usually performed using a purely empirical approach. In this work, we demonstrate the application of a rational approach based on chromatographic theory to prioritize operating parameters. Both methodologies, empirical and rational, were performed to evaluate a specific ion‐exchange chromatography operation for the preparative separation of closely related protein species. We show that the application of the rational approach has the potential to accelerate the evaluation and significantly reduce the amount of analytical testing needed. Biotechnol. Bioeng. 2007; 98: 201–210. © 2007 Wiley Periodicals, Inc.
The role of the surgeon in whether patients with lymph node‐positive colon cancer see a medical oncologist
Authors: Luo Ruili , Giordano Sharon H. , Zhang Dong D. , Freeman Jean , Goodwin James S. 
Published: February 2007

AbstractBACKGROUND.Chemotherapy improves survival for patients with stage III colon cancer, but some older patients with lymph node‐positive colon cancer do not see a medical oncologist and, thus, do not receive adjuvant chemotherapy.METHODS.To evaluate the role of the surgeon in determining referrals to medical oncology among patients with stage III colon cancer, the authors conducted a retrospective cohort study of 6158 patients aged ≥66 years who were diagnosed with stage III colon cancer from 1992 through 1999 by using the Surveillance, Epidemiology, and End Results‐Medicare linked database. Multilevel analysis was used to simultaneously model variations in patients' seeing a medical oncologist at the patient and surgeon levels.RESULTS.Twenty‐one percent of the total variance in seeing a medical oncologist was attributable to the surgeon after adjusting for available patient, tumor, and surgeon characteristics. The individual surgeon characteristics that significantly predicted whether the patient saw a medical oncologist were year since graduation (≤10 years vs >20 years; hazard ratio [HR], 1.60; 95% confidence interval [95% CI], 1.19–2.16), practicing in a teaching hospital (yes vs. no: HR; 1.30; 95% CI, 1.07–1.58), and volume of patients with colon cancer (<30 patients vs ≥121 patients; HR, 0.66; 95% CI, 0.46–0.94). Surgeon sex, race, board certification, and type of practice were not independent predictors of medical oncology referral.CONCLUSIONS.Surgeons accounted for approximately 20% of the variation in patients seeing a medical oncologist. Interventions at the level of the surgeon may be appropriate to improve the care of patients with colon cancer. Cancer 2007 © 2007 American Cancer Society.
Kinetic Isotope Effects in Complex Reaction Networks: Formic Acid Electro‐Oxidation
Authors: Chen Yan‐Xia , Heinen Martin , Jusys Zenonas , Behm Rolf Jürgen 
Published: February 2007

AbstractThe determination of kinetic isotope effects (KIEs) for different reaction pathways and steps in a complex reaction network, where KIEs may affect the overall reaction in various different ways including dominant and minority pathways or the buildup of a reaction‐inhibiting adlayer, is demonstrated for formic acid electro‐oxidation on a Pt film electrode by quantitative electrochemical in situ IR spectroscopic measurements under controlled mass‐transport conditions. The ability to separate effects resulting from different contributions—which is not possible using purely electrochemical kinetic measurements—allows conclusions on the nature of the rate‐limiting steps and their transition state in the individual reaction pathways. The potential‐independent values of ≈1.9 for the KIE of formic acid dehydration (COad formation) in the indirect pathway and ≈3 for the COad coverage‐normalized KIE of formic acid oxidation to CO2 (direct pathway) indicate that 1) CH bond breaking is rate‐limiting in both reaction steps, 2) the transition states for these reactions are different, and 3) the configurations of the transition states involve rather strong bonds to the transferred D/H species, either in the initial or in the final state, for the direct pathway and—even more pronounced—for formic acid dehydration (COad formation).
Synthesis of SrMnO3 powders with different morphologies by hydrothermal method
Authors: Zhu Jing‐Sen , Liu Jing‐Bing , Wang Hao , Zhu Man‐Kang , Yan Hui 
Published: February 2007

AbstractBy using two different reagents as the starting materials, SrMnO3 crystallines with two different morphologies rhombus‐like and rod‐like, have been directly synthesized by hydrothermal conditions. The effects of the hydrothermal parameters on the quality of the SrMnO3 samples were given for the fist time. And a preparative mechanism for the formation of different morphologies using different reagents during the hydrothermal reaction has been discussed. (© 2007 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
Properties of solution grown PbI2 layers embedded in PVA
Authors: Ponpon J. P. , Amann M. 
Published: February 2007

AbstractPolycrystalline lead iodide layers with crystallites in the micrometer range have been prepared using a solution growth method from water and polyvinyl alcohol. Structural, electrical and optical measurements have been performed to characterize these layers and compare their properties to those of polycrystalline films prepared by solution growth in pure water. Most of these properties are very similar. The main difference comes from the photoresponse: that of films prepared with PVA remains high but presents an unusual behaviour with temperature. This has been related to the presence of a trapping/recombination energy level in the band gap. (© 2007 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
Applications of Microplasmas and Microreactor Technology
Authors: Kogelschatz U. 
Published: February 2007

AbstractDuring the last decade a number of microcavity plasma devices have been developed. Examples are microhollow cathode (MHC) discharges and cathode boundary layer (CBL) discharges proposed by Schoenbach, capillary plasma electrode (CPE) discharges proposed by Kunhardt and Becker, and micro‐structured electrode arrays (MSEs) introduced by Gericke and Penache. Arrays of microplasmas based on silicon, ceramic, or metal/polymer structures were investigated by Eden, Frame, Park and coworkers. A breakthrough in the life expectancy of such devices was achieved when all metal electrodes were covered by dielectrics, thus combining dielectric‐barrier discharge technology with microcavity plasma devices.The advantage of this technology is that large numbers of miniature atmospheric‐pressure non‐equilibrium discharges can be operated in parallel. Applications include emitters for visible and UV radiation, photodetectors, sensors, decontamination, surface modification, etching, film deposition, generation of nanoparticles. Operated in different gas mixtures many of these devices proved to be efficient emitters of ultraviolet excimer radiation. If a small gas flow is fed through these microplasmas applications for plasmachemical synthesis and pollution control become feasible. Novel applications are expected from the combination of microreactor technology with non‐equilibrium plasma chemistry. Doping or coating of the dielectric surfaces results in additional catalytic effects. (© 2007 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
Recent Progress in Dielectric Barrier Discharges for Aerodynamic Flow Control
Authors: Font G. I. , Morgan W. L. 
Published: February 2007

AbstractPlasma actuators are electrical devices that use an atmospheric pressure dielectric barrier discharge for flow control. They have been employed successfully to promote boundary layer attachment. Simulations have been carried out of a plasma actuator using Direct‐Simulation‐Monte‐Carlo and Particle‐in‐Cell methods. This work summarizes some recent results including: 1) the method by which force is imparted by the actuator to the neutral flow, 2) the effect of electronegative gasses, such as oxygen, and 3) the effects on the neutral flow of the plasma force. (© 2007 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
RF Capillary Jet ‐ a Tool for Localized Surface Treatment
Authors: Foest R. , Kindel E. , Lange H. , Ohl A. , Stieber M. , Weltmann K.‐D. 
Published: February 2007

AbstractThe UV/VUV spectrum of a non‐thermal capillary plasma jet operating with Ar at ambient atmosphere and the temperature load of a substrate exposed to the jet have been measured. The VUV radiation is assigned to N, H, and O atomic lines along with an Ar*2 excimer continuum. The absolute radiance (115‐200 nm) of the source has been determined. Maximum values of 880 μW/mm2sr are obtained. Substrate temperatures range between 35 °C for low powers and high gas flow conditions and 95 °C for high powers and reduced gas flow. The plasma source (13.56, 27.12 or 40.78 MHz) can be operated in Ar and in N2. The further addition of a low percentage of silicon containing reactive admixtures has been demonstrated for thin film deposition. Several further applications related to surface modification have been successfully applied. (© 2007 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
Prestin–prestin and prestin–GLUT5 interactions in HEK293T cells
Authors: Wu Xudong , Currall Benjamin , Yamashita Tetsuji , Parker Lisan L. , Hallworth Richard , Zuo Jian 
Published: February 2007

AbstractThe remarkable hearing sensitivity and frequency selectivity in mammals is attributed to cochlear amplifier in the outer hair cells (OHCs). Prestin, a membrane protein in the lateral wall of OHC plasma membrane, is required for OHC electromotility and cochlear amplifier. In addition, GLUT5, a fructose transporter, is reported to be abundant in the plasma membrane of the OHC lateral wall and has been originally proposed as the OHC motor protein. Here we provide evidence of interactions between prestin/prestin and prestin/GLUT5 in transiently transfected HEK293T cells. We used a combination of techniques: (1) membrane colocalization by confocal microscopy, (2) fluorescence resonance energy transfer (FRET) by fluorescence activated cell sorting (FACS), (3) FRET by acceptor photobleaching, (4) FRET by fluorescence lifetime imaging (FRET–FLIM), and (5) coimmunoprecipitation. Our results suggest that homomeric and heteromeric prestin interactions occur in native OHCs to facilitate its electromotile function and that GLUT5 interacts with prestin for its elusive function. © 2007 Wiley Periodicals, Inc. Develop Neurobiol, 2007
Increased natural cytotoxicity receptor expression and relevant IL‐10 production in NK cells from chronically infected viremic HCV patients
Authors: De Maria Andrea , Fogli Manuela , Mazza Stefania , Basso Monica , Picciotto Antonio , Costa Paola , Congia Sonia , Mingari Maria Cristina , Moretta Lorenzo 
Published: February 2007

AbstractHepatitis C virus (HCV) readily establishes high‐level lifelong persistent infection in the majority of immunocompetent adults with failure of HCV‐specific CD8+ CTL to clear viral replication. Virus‐induced conditioning of innate immune responses is a possible mechanism that may contribute to the impairment of virus‐specific CD8+ CTL responses. Here, we analyzed whether triggering of NK cell receptor expression and function is affected during chronic viremic HCV infection. Flow cytometric analysis of purified resting peripheral NK cells showed no evidence of NK cell activation, while analysis of natural cytotoxicity receptors (NCR) showed that NK cells from HCV‐infected patients had selective increased expression of NKp30 and NKp46. NK cells had corresponding conserved cytotoxic activity against all targets with the exception of HepG2 hepatoma cells. Freshly separated NK cells from HCV patients showed significant production of IL‐10 and normal concentrations of IFN‐γ upon cell‐mediated triggering. Thus, increased expression of NKp30 during HCV infection with increased IL‐10 production could contribute, once NK cells localize in the liver, to a NK‐DC crosstalk leading to skewing of subsequent adaptive immune responses and lack of virus control.
Functional and biophysical characterization of an HLA‐A*6801‐restricted HIV‐specific T cell receptor
Authors: Gostick Emma , Cole David K. , Hutchinson Sarah L. , Wooldridge Linda , Tafuro Sabrina , Laugel Bruno , Lissina Anna , Oxenius Annette , Boulter Jonathan M. , Price David A. , Sewell Andrew K. 
Published: February 2007

AbstractHLA‐A*6801 exhibits several unusual features. First, it is known to bind weakly to CD8 due to the presence of an A245V substitution in the α3 domain. Second, it is able to accommodate unusually long peptides as a result of peptide ‘kinking’ in the binding groove. Third, CD8+ cytotoxic T lymphocytes that recognise HLA‐A*6801‐restricted antigens can tolerate substantial changes in the peptide sequence without apparent loss of recognition. In addition, it has been suggested that HLA‐A68‐restricted TCR might bind with higher affinity than other TCR due to their selection in the presence of a decreased contribution from CD8. Here we (1) examine monoclonal T cell recognition of an HLA‐A*6801‐restricted HIV‐1 Tat‐derived 11‐amino acid peptide (ITKGLGISYGR) and natural variant sequences thereof; (2) measure the affinity and kinetics of a TCR/pHLA‐A68 interaction biophysically for the first time, showing that equilibrium binding occurs within the range previously determined for non‐HLA‐A68‐restricted TCR (KD approx. 7 μM); and (3) show that “normalization” of the non‐canonical HLA‐A*6801 CD8‐binding domain enhances recognition of agonist peptides without inducing non‐specific activation. This latter effect may provide a fundamental new mechanism with which to enhance T cell immunity to specific antigens.
Immunoregulatory role of Jα281 T cells in aged mice developing lupus‐like nephritis
Authors: Sireci Guido , Russo Domenica , Dieli Francesco , Porcelli Steven A. , Taniguchi Masaru , La Manna Marco Pio , Di Liberto Diana , Scarpa Francesco , Salerno Alfredo 
Published: February 2007

AbstractSystemic lupus erythematosus (SLE) is an autoimmune disease characterized by the emergence of autoreactive T cells. Humans and mice with SLE have reduced numbers of CD1d‐restricted invariant natural killer T (iNKT) cells, suggesting a key role for these cells in its immunopathogenesis. This subset uses an invariant TCR constituted by Vα14Jα281 chains paired with some Vβ domains. The regulatory role for iNKT cells in non‐autoimmune mice was suggested by our previous results showing that aged Jα281 knockout (KO) mice produce anti‐dsDNA. Here we show that old Jα281 KO mice have proteinuria and antibodies against dsDNA and cardiolipin. Histological analysis of Jα281 KO mice revealed glomeruli damage and deposition of C3c and IgG, mainly of the IgG3 subclass. In spleens of aged Jα281 KO mice there is an increase of activated marginal zone B cells. The evolution of lesions may depend on the age‐associated increase of autoantibodies production, preferentially IgG3, mainly secreted by marginal zone B cells. Our results provide the first evidence of a lupus‐like syndrome in non‐autoimmune mice, supporting an age‐related immunoregulatory role of Jα281+ cells, probably associated with the activation of marginal zone B cells.
Acetylide Addition to Bridging Vinyliminium Ligands in Dinuclear Complexes
Authors: Busetto Luigi , Marchetti Fabio , Zacchini Stefano , Zanotti Valerio 
Published: February 2007

AbstractThe (vinyliminium)diiron complexes [Fe2{μ‐η1:η3‐Cγ(R′)=Cβ(R′)Cα=N(Me)(R)}(μ‐CO)(CO)(Cp)2][SO3CF3] [R = Xyl, R′ = Me (1a); R = Xyl, R′ = Et (1b); R = R′ = Me (1c); R = Me, R′ = Et (1d); R = CH2Ph, R′ = Me (1e); Xyl = 2,6‐Me2C6H3] undergo regio‐ and stereoselective addition by lithium acetylides. Addition of LiC≡CR″ (R″ = Tol, Ph, SiMe3; Tol = 4‐MeC6H4) to trans‐1a occurs at the Cβ atom of the vinyliminium ligand and results in the formation of the bis(alkylidene) complexes cis‐[Fe2{μ‐η1:η2‐C(Me)C(Me)(C≡CR″)CN(Me)(Xyl)}(μ‐CO)(CO)(Cp)2] [R″ = Tol (2a), Ph (2b), SiMe3 (2c)]. The molecular structure of 2a has been determined by X‐ray diffraction. Similarly, the diruthenium complex [Ru2{μ‐η1:η3‐C(Me)=C(Me)C=N(Me)(Xyl)}(μ‐CO)(CO)(Cp)2][SO3CF3] (3) reacts with LiC≡CTol to give the bis(alkylidene) compound[Ru2{μ‐η1:η2‐C(Me)C(Me)(C≡CTol)CN(Me)(Xyl)}(μ‐CO)(CO)(Cp)2] (4). Conversely, 1c and 1d undergo acetylide attack at the Cα atom of the vinyliminium ligand to yield the allylidenecomplexes [Fe2{μ‐η1:η3‐C(R′)C(R′)C(C≡CR″)N(Me)2}(μ‐CO)(CO)(Cp)2] [R′ = Me, R″ = Tol (5a); R′ = Me, R″ = Ph (5b); R′ = Me, R″ = SiMe3 (5c); R′ = Me, R″ = nBu (5d); R′ = Me, R″ = C(Me)=CH2 (5e); R′ = Me, R″ = H (5f); R′ = Et, R″ = Tol (5g); R′ = Et, R″ = Ph (5h); R′ = Et, R″ = SiMe3 (5i); R′ = Et, R″ = C(Me)=CH2 (5j)]. Analogously, the reaction of 1e with LiC≡CPh affords [Fe2{μ‐η1:η3‐C(Me)C(Me)C(C≡CPh)N(Me)(CH2Ph)}(μ‐CO)(CO)(Cp)2] (6). The molecular structure of 5h has been determined by X‐ray diffraction. Finally, 1b, in both its cis and trans forms, undergoes acetylide attack at the Cα atom of the vinyliminium ligand to give the complexes[Fe2{μ‐η1:η3‐C(Et)C(Et)C(C≡CR″)N(Me)(Xyl)}(μ‐CO)(CO)(Cp)2] [R″ = SiMe3 (7a), H (7b)]. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2007)
Metal Complexes Incorporating Monoanionic Bisoxazolinate Ligands: Synthesis, Structures, Reactivity and Applications in Asymmetric Catalysis
Authors: Dagorne Samuel , Bellemin‐Laponnaz Stéphane , Maisse‐François Aline 
Published: February 2007

AbstractThe present contribution reviews the synthesis, structures, reactivity and applications in asymmetric catalysis of metal complexes containing monoanionic bisoxazolinate ligands. The anionic and bidentate bisoxazolinate ligand, which may be seen as a nitrogenated version of the acetylacetonate unit and may also be closely related to the diketiminate bidentate ligand, appears to exhibit a rich and versatile coordination chemistry with various metal centers. These excellent coordination properties, combined with the ready accessibility of chiral bisoxazolinate ligands in an enantiomerically pure form, has opened the way to various applications in asymmetric catalysis involving this class of bidentate ligands. Thus, the use of chiral bisoxazolinate ligands in asymmetric catalysis constitutes a central part of this review. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2007)
RuCl2(dmso)4 Catalyzes the Solvent‐Free Indirect Friedländer Synthesis of Polysubstituted Quinolines from Alcohols
Authors: Martínez Ricardo , Ramón Diego J. , Yus Miguel 
Published: February 2007

AbstractThe first synthesis of polysubstituted quinoline derivatives from aromatic or aliphatic alcohols with RuCl2(dmso)4 as catalyst under solvent‐free conditions is described. The reaction involves the in situ oxidation of alcohols to the corresponding carbonyl compounds through a hydrogen‐transfer, followed by a Friedländer annulation process. The whole process is a mild, efficient, selective, and high‐yielding single‐step procedure. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2007)
Preparation and Electrochemical Study of Modified Carbon Ceramic Electrode with 5‐(4‐Dimethyl amino benzelyden)‐rhodanin for the Determination of Silver
Authors: Majidi M. R. , Asadpour‐Zeynali K. , Hosseini S.‐A. 
Published: February 2007

AbstractThe carbon ceramic technique is a new, simple and reliable way for the preparation of modified electrodes. The carbon ceramic conduct in the presence of graphite powder was recently proposed as a versatile way to obtain tailored electrode materials. In the present study, 5‐(4‐dimethyl amino benzelyden)‐rhodanin (RNSH) was used as a reagent in the preparation of modified carbon ceramic electrode. This electrode was used in the determination of trace amounts of silver by differential pulse anodic stripping voltammetry (DPASV) technique. The best results were obtained under the following optimized conditions: 10 min accumulation, +0.8 V potential accumulation, 50 mV pulse amplitude, 50 mV s−1 scan rate. Applying in the DPASV method at 0.1 M McIlvaine buffer with pH 5.0, linearity was achieved from 10−13 to 10−7 M with limit of detection 4.5×10−14 M. The proposed method was applied to determination of silver in human hair.