bluuebunny/crossref_metadata_2025_split huggingface dataset:
Clinical, socio-demographic, and parental correlates of early autism traits in a community cohort of toddlers
Authors: Gale-Grant Oliver , Chew Andrew , Falconer Shona , França Lucas G. S. , Fenn-Moltu Sunniva , Hadaya Laila , Harper Nicholas , Ciarrusta Judit , Charman Tony , Murphy Declan , Arichi Tomoki , McAlonan Grainne , Nosarti Chiara , Edwards A. David , Batalle Dafnis 
Published: April 2024

AbstractIdentifying factors linked to autism traits in the general population may improve our understanding of the mechanisms underlying divergent neurodevelopment. In this study we assess whether factors increasing the likelihood of childhood autism are related to early autistic trait emergence, or if other exposures are more important. We used data from 536 toddlers from London (UK), collected at birth (gestational age at birth, sex, maternal body mass index, age, parental education, parental language, parental history of neurodevelopmental conditions) and at 18 months (parents cohabiting, measures of socio-economic deprivation, measures of maternal parenting style, and a measure of maternal depression). Autism traits were assessed using the Quantitative Checklist for Autism in Toddlers (Q-CHAT) at 18 months. A multivariable model explained 20% of Q-CHAT variance, with four individually significant variables (two measures of parenting style and two measures of socio-economic deprivation). In order to address variable collinearity we used principal component analysis, finding that a component which was positively correlated with Q-CHAT was also correlated to measures of parenting style and socio-economic deprivation. Our results show that parenting style and socio-economic deprivation correlate with the emergence of autism traits at age 18 months as measured with the Q-CHAT in a community sample.
A hybrid particle swarm optimization algorithm for solving engineering problem
Authors: Qiao Jinwei , Wang Guangyuan , Yang Zhi , Luo Xiaochuan , Chen Jun , Li Kan , Liu Pengbo 
Published: April 2024

AbstractTo overcome the disadvantages of premature convergence and easy trapping into local optimum solutions, this paper proposes an improved particle swarm optimization algorithm (named NDWPSO algorithm) based on multiple hybrid strategies. Firstly, the elite opposition-based learning method is utilized to initialize the particle position matrix. Secondly, the dynamic inertial weight parameters are given to improve the global search speed in the early iterative phase. Thirdly, a new local optimal jump-out strategy is proposed to overcome the "premature" problem. Finally, the algorithm applies the spiral shrinkage search strategy from the whale optimization algorithm (WOA) and the Differential Evolution (DE) mutation strategy in the later iteration to accelerate the convergence speed. The NDWPSO is further compared with other 8 well-known nature-inspired algorithms (3 PSO variants and 5 other intelligent algorithms) on 23 benchmark test functions and three practical engineering problems. Simulation results prove that the NDWPSO algorithm obtains better results for all 49 sets of data than the other 3 PSO variants. Compared with 5 other intelligent algorithms, the NDWPSO obtains 69.2%, 84.6%, and 84.6% of the best results for the benchmark function ($${f}_{1}-{f}_{13}$$

f
1

-

f
13

) with 3 kinds of dimensional spaces (Dim = 30,50,100) and 80% of the best optimal solutions for 10 fixed-multimodal benchmark functions. Also, the best design solutions are obtained by NDWPSO for all 3 classical practical engineering problems.
Identifying acute illness phenotypes via deep temporal interpolation and clustering network on physiologic signatures
Authors: Ren Yuanfang , Li Yanjun , Loftus Tyler J. , Balch Jeremy , Abbott Kenneth L. , Ruppert Matthew M. , Guan Ziyuan , Shickel Benjamin , Rashidi Parisa , Ozrazgat-Baslanti Tezcan , Bihorac Azra 
Published: April 2024

AbstractUsing clustering analysis for early vital signs, unique patient phenotypes with distinct pathophysiological signatures and clinical outcomes may be revealed and support early clinical decision-making. Phenotyping using early vital signs has proven challenging, as vital signs are typically sampled sporadically. We proposed a novel, deep temporal interpolation and clustering network to simultaneously extract latent representations from irregularly sampled vital signs and derive phenotypes. Four distinct clusters were identified. Phenotype A (18%) had the greatest prevalence of comorbid disease with increased prevalence of prolonged respiratory insufficiency, acute kidney injury, sepsis, and long-term (3-year) mortality. Phenotypes B (33%) and C (31%) had a diffuse pattern of mild organ dysfunction. Phenotype B’s favorable short-term clinical outcomes were tempered by the second highest rate of long-term mortality. Phenotype C had favorable clinical outcomes. Phenotype D (17%) exhibited early and persistent hypotension, high incidence of early surgery, and substantial biomarker incidence of inflammation. Despite early and severe illness, phenotype D had the second lowest long-term mortality. After comparing the sequential organ failure assessment scores, the clustering results did not simply provide a recapitulation of previous acuity assessments. This tool may impact triage decisions and have significant implications for clinical decision-support under time constraints and uncertainty.
Natural course of hemodynamically stable hemispheres contralateral to operated hemispheres in adult patients with ischemic moyamoya diseases
Authors: Kang Young Sill , Cho Won-Sang , Nam Sun Mo , Chung Yuwhan , Lee Sung Ho , Kim Kangmin , Kang Hyun-Seung , Kim Jeong Eun 
Published: April 2024

AbstractThe necessity of bilateral bypass in adult moyamoya disease (MMD) remains unclear despite its recommendation for pediatric and hemorrhagic cases. We aimed to investigate the natural course of hemodynamically stable unoperated hemispheres after bypass surgery for symptomatic and hemodynamically unstable hemispheres in adult patients with ischemic MMD. Among 288 patients, the mean age at the first operation of the unstable hemispheres was 40.8 ± 12.2 years. The mean follow-up period was 62.9 ± 46.5 months. 45 patients (15.6%) experienced stroke events in the unoperated hemisphere, consisting of hemorrhagic stroke in 8 (2.8%) and ischemic stroke in 37 (12.8%), including progressive transient ischemic attack in 25 (8.7%) and infarction in 12 (4.2%). Among them, 39 patients (13.5%) underwent bypass surgery. The annual risk of total stroke is 3.0%/patient-year, with 2.5% for ischemic stroke and 0.5% for hemorrhagic stroke. The 5- and 10-year cumulative risks of ischemic stroke were 13.4% and 18.3%, respectively, and those of hemorrhagic stroke were each 3.2%. The natural course of hemodynamically stable hemispheres contralateral to the operated ones appeared fairly good. Additional bypass surgery on the unoperated hemispheres should be considered for symptomatic and hemodynamically unstable hemispheres in adult patients with ischemic MMD during the follow-up.
DON6D: a decoupled one-stage network for 6D pose estimation
Authors: Wang Zheng , Tu Hangyao , Qian Yutong , Zhao Yanwei 
Published: April 2024

AbstractThe six-dimensional (6D) pose object estimation is a key task in robotic manipulation and grasping scenes. Many existing two-stage solutions with a slow inference speed require extra refinement to handle the challenges of variations in lighting, sensor noise, object occlusion, and truncation. To address these challenges, this work proposes a decoupled one-stage network (DON6D) model for 6D pose estimation that improves inference speed on the premise of maintaining accuracy. Particularly, since the RGB images are aligned with the RGB-D images, the proposed DON6D first uses a two-dimensional detection network to locate the interested objects in RGB-D images. Then, a module of feature extraction and fusion is used to extract color and geometric features fully. Further, dual data augmentation is performed to enhance the generalization ability of the proposed model. Finally, the features are fused, and an attention residual encoder–decoder, which can improve the pose estimation performance to obtain an accurate 6D pose, is introduced. The proposed DON6D model is evaluated on the LINEMOD and YCB-Video datasets. The results demonstrate that the proposed DON6D is superior to several state-of-the-art methods regarding the ADD(-S) and ADD(-S) AUC metrics.
Diagnostic performance of PIVKA-II in identifying recurrent hepatocellular carcinoma following curative resection: a retrospective cohort study
Authors: Zhu Wenfeng , Wang Weilong , Zheng Wenjie , Chen Xiaolong , Wang Xiaowen , Xie Juping , Jiang Shijie , Chen Haoqi , Zhu Shuguang , Xue Ping , Jiang Xiaofeng , Li Hua , Wang Genshu 
Published: April 2024

AbstractProtein induced by vitamin K absence or antagonist II (PIVKA-II) plays a critical role in the diagnosis of hepatocellular carcinoma (HCC), however, studies on its efficacy in diagnosing recurrent HCC were rarely found. A multicenter, retrospective, and observational study was conducted. During the overall follow-up of 5 years, HCC patients who had curative resection were monitored every 3 months in the first year post-surgery and every 6 months thereafter if no recurrence occurred. Tumor markers were collected at the diagnosis of recurrence for those with recurrence and at the last follow-up for those without recurrence. The median serum levels of PIVKA-II and AFP in the recurrence group were significantly higher than those in the non-recurrence group (PIVKA-II: 84.62 vs. 18.76 mAU/ml, p < 0.001; AFP: 4.90 vs. 3.00 ng/ml, p < 0.001) and there is a significant correlation between PIVKA-II and AFP (R = 0.901, p < 0.001). PIVKA-II showed better accuracy than AFP in the diagnosis of overall recurrent HCC (AUC: 0.883 vs. 0.672; p < 0.0001), but also in patients with negative PIVKA-II before curative resection (AUC: 0.878 vs. 0.680, p = 0.001). Clinician should pay more attention to serum PIVKA-II values when following patients after curative HCC resection to detect early recurrence.Clinical trial registration: ChiCTR2300070874
Lead-halide perovskite quantum dots embedded in mesoporous silica as heterogeneous photocatalysts combined with organocatalysts for asymmetric catalysis
Authors: Ren Hao , Li Yi-Ming , Li Wen-Jing , Zhai Qing-Chao , Cheng Lin 
Published: April 2024

CsPbBr3 quantum dots embedded in KIT-6 to form silica-shell-protected heterogeneous photocatalysts, which were further combined with chiral organocatalysts forming dual-catalysts to explore the activity and stereoselectivity in asymmetric catalysis.
Multiple adaptive factors based interacting multiple model estimator
Authors: Sun Minxing , Duan Qianwen , Xia Wanrun , Bao Qiliang , Mao Yao 
Published: April 2024

AbstractIn the field of optoelectronic tracking, precisely modeling the motion equations of the tracked target is often challenging, and in some cases, they may even be entirely unknown. This necessitates the use of a robust state estimator for accurate state estimation. Additionally, atmospheric turbulence, variations in illumination, and intricate observation backgrounds may introduce a significant increase in observation noise for the tracked target. To address these challenges, one approach is to introduce adaptive factors, such as the Mahalanobis method, into the robust state estimator to enhance estimation accuracy. However, further exploration has revealed that adaptive factors designed using different methods offer unique advantages in scenarios with varying levels of noise amplification. In this paper, different adaptive factors are further combined using an interacting multiple model approach, allowing the designed state estimator to exhibit stronger adaptability to noise amplification. The stability and effectiveness of this algorithm are validated through program simulations, double reflection mirror experiment, and drone trace prediction, demonstrating its applicability and reliability in diverse scenarios.
RETRACTED: Ecofriendly Approaches in nanomaterial synthesis for sustainable healthcare applications
Authors: Verma Rajan , Kumar Gaurav , Upadhyay Viyat Varun , Ratur Anuj , Rao A.L.N. , Kumar Anil , Boob Nandini Shirish 
Published: April 2024

This paper has been formally retracted from publication by the Publisher due to the fact that the scientific relevance of this work is questionable.
Request approved by the Publisher on October 9, 2024.
Befragung zum Verordnungsverhalten in der Kompressionstherapie in Deutschland
Authors: Protz Kerstin , Eder Stephan , Läuchli Severin , Stücker Markus , Traber Jürg , Dissemond Joachim 
Published: April 2024

Zusammenfassung
Ziel der Studie Obwohl die Wirksamkeit der Kompressionstherapie wissenschaftlich gut belegt ist, gibt es in der praktischen Umsetzung oft Defizite. In dieser Studie sollte daher die Praxis der Versorgung und Verordnung in der Kompressionstherapie bei Menschen mit Ulcus cruris venosum untersucht werden.
Methodik Diese prospektive Querschnittsstudie wurde deutschlandweit mit einem Fragebogen während Schulungen zur Kompressionstherapie, auf Fachtagungen sowie Kongressen mit Versorgern aus dem pflegerischen und ärztlichen Bereich durchgeführt.
Ergebnisse Ausgewertet wurden Rückmeldungen von 320 Versorgern. Als größtes Hindernis (68%) einer optimalen Kompressionstherapie wurde die mangelnde Akzeptanz der Patienten beschrieben. Bei den Verordnungen werden mit 62% am häufigsten Kurzzugbinden mit/ohne Unterpolsterung verwendet; Mehrkomponentensysteme werden lediglich zu 6% und medizinische adaptive Kompressionssysteme zu 1% verordnet. Insgesamt 27% der Befragten messen Beinumfänge zur Kontrolle des Behandlungserfolgs. Kurzzugbinden werden bei 46% bis zur Abheilung des Ulcus cruris venosum verordnet.
Schlussfolgerung Diese Daten über die Verordnung und Anwendung von Kompressionsmaterialien zeigen erhebliche Defizite bei gleichzeitig mangelhaftem Problembewusstsein. Nur durch mehr Wissen sowie eine sachgerechte Auswahl und Anwendung zeitgemäßer Therapieoptionen lassen sich die Qualität und Akzeptanz der Kompressionstherapie erhöhen.
Implantação do protocolo de recuperação rápida para artroplastia total do quadril em hospital público do estado de São Paulo – Brasil
Authors: Lima Leandro Gregorut , Sampaio Barbara Fialho Carvalho , Neves Marco Aurélio Silvério , Barbosa Alexandre Póvoa , Seid Victor Edmond , Lopes Fernanda Degobbi T. Q. S. 
Published: April 2024

Resumo
Objetivo Avaliar os resultados da implantação do Protocolo de Recuperação Rápida (PRR), prática médica baseada em evidências científicas, para cirurgia eletiva de artroplastia total do quadril principalmente comparando à Taxa Média de Internação Hospitalar nacional de 7.1 dias.
Métodos 98 pacientes submetidos a cirurgia eletiva de artroplastia total do quadril pela via direta anterior, via anterolateral e via posterior foram incluídos no PRR no período de dezembro de 2018 a março de 2020 sendo acompanhados no pré-operatório, intraoperatório e pós-operatório imediato.
Resultados a Taxa Média de Permanência Hospitalar foi de 2,8 dias, sendo 2,1 dias para a Via de Acesso Anterior, 3,0 dias para via de acesso anterolateral e 4,1 dias para via de acesso posterior. O tempo médio de cirurgia foi de 90 minutos, 19 (19,39%) dos pacientes foram encaminhados à UTI no pós-operatório, no entanto nenhum deles operado pela via direta anterior. Não tivemos casos de trombose venosa profunda (TVP), embolia pulmonar (TEP) ou lesão neurológica, 19 (19,39%) pacientes tiveram sangramento pós-operatório com necessidade de troca de curativo, 4 (4,08%) necessidade de transfusão sanguínea, 2 (2,04%) pacientes apresentaram instabilidade do implante, 1(1,02%) paciente teve fratura durante a cirurgia e 1(1,02%) paciente faleceu por complicações cardíacas.
Conclusão O PRR pode ser uma alternativa viável para diminuir o tempo de internação e as complicações pós-operatórias imediatas para a cirurgia eletiva de artroplastia total do quadril diminuindo 2 a 3 vezes o tempo de internação dos pacientes quando comparado com a média nacional de 7,1 dias.
Resultado funcional da reconstrução do LCA após habilitação pré-reconstrução vs. nenhuma pré-habilitação: Revisão sistemática e metanálise
Authors: Aryana I Gusti Ngurah Wien , Febyan Febyan , Dimitri Dominicus , Limena Shianita , Kuswara Leonardus William 
Published: April 2024

Resumo
Objetivo O objetivo deste estudo é analisar as necessidades de pré-habilitação cirúrgica em pacientes submetidos à reconstrução do LCA.
Métodos Os relatórios das bases de dados foram pesquisados entre 2018 e 2023, utilizando PubMed, base de dados da biblioteca Cochrane, Medline e outros artigos publicados. Uma análise estatística foi feita utilizando-se o Review Manager.
Resultados O grupo de pré-habilitação cirúrgica apresenta pontuação KOOS pós-operatória de 2 anos significativamente maior em todos os subescores e na média total da pontuação, dor (p < 0,0001), sintomas (p < 0,0001), AVD (p < 0,0001). 0,0001), esportes e recreação (p < 0,0001), QV (p < 0,0001) e média total do escore KOOS (p < 0,0001). Em contrapartida, o grupo de habilitação pré-operatória apresenta pontuação insignificantemente maior no escore de Lysholm pós-operatório de 3 meses (p = 0,12).
Conclusão Esta metanálise conclui que a pré-habilitação cirúrgica pode proporcionar melhores resultados pós-operatórios a longo prazo, no entanto, pode não proporcionar um resultado significativo a curto prazo. Recomenda-se adicionar a pré-habilitação cirúrgica como uma diretriz para o manejo da lesão do LCA para melhorar o resultado a longo prazo dos pacientes com lesão do LCA submetidos ao procedimento de reconstrução do LCA.
Epidemiologia das lesões do joelho em atletas de beisebol do estado de São Paulo
Authors: Arashiro Victor Kenzo , Aguilar Karin Coca , Xu Tian , Rabelo Nayra Deise dos Anjos , Netto Alfredo dos Santos , Cury Ricardo de Paula Leite 
Published: April 2024

Resumo
Objetivo Identificar as principais queixas e lesões de joelho associadas ao beisebol, e sua prevalência em atletas de beisebol no estado de São Paulo.
Métodos Estudo epidemiológico desenvolvido por meio da análise de dados obtidos por um questionário online, entre os anos de 2019 e 2022, distribuído entre atletas de beisebol do estado de São Paulo.
Resultados Noventa e oito atletas participaram do estudo, com média de 24,3 anos de idade, sendo que 85,72% eram homens. As etnias mais prevalentes foram os amarelos (50%) e brancos (42,86%), e a maioria dos atletas possuía ensino superior incompleto ou completo (75,5%). Um total de 88,77% treinava há mais de 1 ano e 40,82% atuavam em mais de uma posição. Mais da metade praticava simultaneamente outro esporte. Um total de 66,32% dos atletas apresentava queixas ou sintomas no joelho e 37,75% já haviam sofrido alguma lesão no joelho associada à prática do beisebol através de diversos mecanismos (contato com solo, contato com outro jogador, sem contato). Um total de 59,45% dos atletas precisou ser afastado da prática devido às queixas, sintomas ou lesões apresentadas.
Conclusão Dos atletas entrevistados, 66,32% apresentaram alguma queixa no joelho e 37,75% já tiveram alguma lesão diagnosticada nessa articulação, sendo as mais prevalentes as lesões meniscais e as ligamentares. A taxa de lesões foi maior no primeiro ano de prática.
Tratamento de fraturas do planalto tibial com fixador externo circular: Uma análise comparativa de duas formas de montagem
Authors: Berto Leonardo , Palma Gustavo Henrique de Barros , Silva André Crippa da , Rodrigues Mauro Remulo Grinfelder Brunel , Amorim Renato , Cardoso Gracielle Silva 
Published: April 2024

Resumo
Objetivo Comparar os resultados funcionais entre duas técnicas de fixação externa circular utilizadas no tratamento de fraturas complexas da extremidade proximal da tíbia.
Materiais e Métodos Trata-se de um estudo de coorte retrospectivo, com 51 pacientes submetidos ao tratamento cirúrgico de fraturas complexas do planalto tibial com fixador externo circular. Os pacientes foram divididos em dois grupos: 12 pacientes tratados com a técnica clássica e 39 pacientes tratados com a técnica simplificada. As variáveis analisadas incluíram idade, sexo, mecanismo da lesão, energia do trauma, lesões associadas, tipo de fixador, tempo de uso do fixador e resultados clínico-radiográficos. A técnica clássica lança mão principalmente de fios de Kirschner transfixantes, e a simplificada substitui os fios de Kirschner por pinos de Schanz no bloco distal do fixador externo circular.
Resultados A partir da comparação das montagens, não encontramos diferenças estatisticamente significativas (p > 00,5) entre os dois grupos em relação aos resultados clínico-radiográficos, incluindo a consolidação da fratura, a qualidade da redução da fratura articular, a amplitude de movimento, a discrepância residual na medida dos membros inferiores e a dor do paciente no pós-operatório.
Conclusão Sugerimos que a técnica simplificada, utilizando pinos de Schanz no lugar dos fios de Kirschner, pode ser uma alternativa viável e eficaz no tratamento de fraturas complexas da extremidade proximal da tíbia com fixador externo circular. Essa abordagem simplificada pode oferecer benefícios, como menor taxa de infecção e maior conforto para o paciente, sem comprometer os resultados clínicos e radiográficos, o que justifica, o seu uso.
Epitaxial growth of α-(AlxGa1−x)2O3 by suboxide molecular-beam epitaxy at 1 µm/h
Authors: Steele Jacob , Azizie Kathy , Pieczulewski Naomi , Kim Yunjo , Mou Shin , Asel Thaddeus J. , Neal Adam T. , Jena Debdeep , Xing Huili G. , Muller David A. , Onuma Takeyoshi , Schlom Darrell G. 
Published: April 2024

We report the use of suboxide molecular-beam epitaxy (S-MBE) to grow α-(AlxGa1−x)2O3 films on (110) sapphire substrates over the 0 &lt; x &lt; 0.95 range of aluminum content. In S-MBE, 99.98% of the gallium-containing molecular beam arrives at the substrate in a preoxidized form as gallium suboxide (Ga2O). This bypasses the rate-limiting step of conventional MBE for the growth of gallium oxide (Ga2O3) from a gallium molecular beam and allows us to grow fully epitaxial α-(AlxGa1−x)2O3 films at growth rates exceeding 1 µm/h and relatively low substrate temperature (Tsub = 605 ± 15 °C). The ability to grow α-(AlxGa1−x)2O3 over the nominally full composition range is confirmed by Vegard’s law applied to the x-ray diffraction data and by optical bandgap measurements with ultraviolet–visible spectroscopy. We show that S-MBE allows straightforward composition control and bandgap selection for α-(AlxGa1−x)2O3 films as the aluminum incorporation x in the film is linear with the relative flux ratio of aluminum to Ga2O. The films are characterized by atomic-force microscopy, x-ray diffraction, and scanning transmission electron microscopy (STEM). These α-(AlxGa1−x)2O3 films grown by S-MBE at record growth rates exhibit a rocking curve full width at half maximum of ≊ 12 arc secs, rms roughness &lt;1 nm, and are fully commensurate for x ≥ 0.5 for 20–50 nm thick films. STEM imaging of the x = 0.78 sample reveals high structural quality and uniform composition. Despite the high structural quality of the films, our attempts at doping with silicon result in highly insulating films.