bluuebunny/crossref_metadata_2025_split huggingface dataset:
Synthesis of Silver‐Doped Titanium Dioxide Nanoparticles by Sol‐Gel and Coprecipitation Techniques: Evaluation of Antimicrobial Activity and Cytotoxic Effects
Authors: Shabaninia Mitra , Khorasani Manouchehr , Baniyaghoob Sahar 
Published: April 2024

AbstractTiO2 nanoparticles are effective alternative to the antibiotics. The quick recombination of the photogenerated charges and the inefficient exploitation of visible light remain the major problems limiting their large‐scale applications. Modifying the TiO2 with Silver that acting as an electron trap, plays an important role in reducing the recombination of TiO2 charges and shift its photo‐response to the visible light region. The present work aims to synthesize AgTiO2 nanoparticles using sol‐gel and coprecipitation methods and evaluating the antimicrobial behavior of them. Also, to find the optimal conditions based on the anatase phase of TiO2 due to its higher antimicrobial activity than the rutile form. Among Ag‐TiO2 nanoparticles obtained, the one prepared by sol‐gel method at 450 °C and PH=8–8.5 exhibits the best antimicrobial property. AgTiO2 nanoparticles have been characterized by means X‐ray Diffraction (XRD), Fourier transform infrared spectroscopy (FTIR),scanning electron microscope (SEM), ζ‐potential, dynamic light scattering (DLS) that showing promising results. Zeta potential values −103 mV has been reported that is considered as a stable colloidal suspension system that prevents nanoparticles aggregation. Antimicrobial behavior of them were evaluated using Diffusion (Agar disk‐diffusion), Dilution (MIC) and Bacterial colony counting methods and diameter of the inhibitory zone 15 mm and minimum inhibitory concentration 5 mg/ml was observed.Colony count results indicated that AgTiO2 able to kill bacteria at the lowest concentration of 5 mg/ml. Outcomes of MTT assay (measure cell cytoxicity) suggesting the absence of toxicity in living Hfff cells (as a normal human fibroblast) while surviving L929 cells (as a cancer cell line originated from mouse fibroblast cells). After 24 and 48 h incubation from 100 % to 77.3 % and 57.2 % was reduced respectively. This indicates that Ag/TiO2 nanoparticles act as a anticancer drug and have inherent selective toxicity nature towards cancer cells while posing no effect to normal cells. AgTiO2 nanoparticles are synthesized using sol‐gel and coprecipitation methods. The sample prepared by the sol‐gel method at a temperature of 450 °C and pH=8.5, which corresponds to the anatase phase of TiO2 synthesis, shows the best antimicrobial properties and acts as an anticancer drug with inherent selective toxicity nature towards cancer cells while posing no effect on normal cells.
Enhanced Visible Light Photocatalytic Activity of Exfoliated Boron‐TiO2 Composite for Degradation of Rhodamine B and Nitrogen Fixation
Authors: Ramteke Pritam , Bhoyar Toshali , Umare Suresh S. 
Published: April 2024

AbstractThe design of an efficient, recyclable, visible light photocatalytic system was examined as a viable new green way to address environmental challenges such as removal of pollutants from wastewater and N2 fixation. The exfoliated boron (Bexf)‐Titanium oxide (TiO2) composite visible light active photocatalysts were successfully constructed via a simple wet chemical method by utilizing acetone as a solvent. The composite was evaluated for the photodegradation of Rhodamine B (RhB) dye and reduction of N2, which exhibits improved photocatalytic activity for degradation of RhB as well as for reduction of N2. Experiments with different quenchers indicate that the photogenerated superoxide radical anion (O2⋅−) plays a significant role in the degradation of RhB as well as for N2 reduction reactions. The composite catalyst shows good photostability and there is no significant reduction of the catalyst activity for dye degradation up to 4 cycles of reaction. This work affords a significant view into the design of reusable TiO2 composite materials for photocatalytic RhB degradation and nitrogen fixation.
Synthesis, Biological Evaluation, Molecular Docking and ADME Profiling of Methylpiperidin‐4‐ylphenyl‐nicotinamide Derivatives
Authors: Mohan Mulik Baban , Srivastava Noopur , Pendharkar Dhananjay 
Published: April 2024

AbstractIn this paper, we designed, synthesized, and biologically screened a series of methyl‐piperidine‐phenyl‐nicotinamide derivatives with the aim of novel derivatives as effective anticancer agents. Compounds (9 a), (9 e) and (9 k) exhibited potent anticancer activity with an IC50 value of 5.9 μM, 5.9 μM and 5.0 μM, respectively using MV411 (Acute Myeloid Leukemia) and K562 (Chronic Myeloid Leukemia) cell line. Our docking studies show good binding affinity of these compounds for ABL1 kinase. Furthermore, these compounds exhibited a favourable in silico ADME profile with good solubility and low clearance in Human Liver Microsomes (HLM). These derivatives represent a promising approach to initiate the development of new anticancer drugs in oncology programs.
A Silver Nanoparticle‐Embedded Tamarind Kernel Gum/Poly (Sodium Acrylate) Nanocomposite for Sustainable Release of Doxycycline
Authors: Rani Indu , Warkar Sudhir G. , Kumar Anil 
Published: April 2024

AbstractThe current work describes an eco‐friendly novel synthesis of silver (Ag) nanoparticles (NPs)/Tamarind kernel gum (TKG)/Poly (sodium acrylate) (PSA) nanocomposite without the use of any toxic materials. It is a one‐step route synthesis of silver nanocomposite hydrogel in which TKG and PSA are cross‐linked using methylene bisacrylamide (MBA) cross‐linker. The developed hydrogels were characterized using XRD, FTIR, UV‐visible, FE‐SEM, and TEM techniques. Doxycycline (dox) was chosen as a model drug for release studies using TKG/PSA and Ag/TKG/PSA nanocomposite. The observation is that Ag NP/TKG/PSA nanocomposite showed a pH‐dependent swelling which is higher at pH 7.4 than at pH 1.2. Similarly, the cumulative drug release percentage (CDR %) using silver nanocomposite is higher at pH 7.4 than at pH 1.2. Also, the presence of Ag NPs decreased the swelling ratio (SR) of TKG/PSA hydrogel, which controls the rate of release of the dox drug. In addition, the dox release kinetics were studied using the Korsmeyer‐Peppas and Higuchi model. It has been found that drug release data was fitted in the Korsmeyer‐Peppas model with a higher value of regression coefficient (R2). Thus, Ag/TKG/PSA nanocomposite showed satisfactory results for sustainable release of doxycycline drug.
Evaluation of Structural, Morphological, Optical and Bactericidal Action of Branched Sm‐Doped CuO Nano‐Lanceolates
Authors: Franklin Rajesh T. S. , Jeyakumar S. C. , Sahaya Jude Dhas S. , Biju C. S. , Aswathappa Sivakumar , Suresh Kumar Raju , Almansour Abdulrahman I. 
Published: April 2024

AbstractOver the years, metal oxides have been leveraged to create several intriguing novel antibacterial active materials such that while finding the ways and means to increase efficiency, rare earth elements are found to have often served as potential optical dopants such that an optimistic en route to achieve the same, branched Sm‐doped CuO nano‐lanceolates were synthesized employing a wet chemical approach. The samples were then annealed at three distinct temperatures, which were fixed to 300 °C, 400 °C, and 500 °C. The nano‐lanceolates have crystallized in the monoclinic phase, according to the XRD analysis. The SEM image of Sm‐doped CuO captured at a magnification of 2 μm reveals a branched morphology, with multiple nano‐lanceolates stacked in a stem. TEM image reveals that the width of a typical nano‐lanceolate attached to a stem and its tip are found to be 87 nm and 212 nm, respectively and the obtained EDS data validate that elements including Cu, Sm, and O are present in the doped sample. The UV‐visible spectra of the annealed samples indicate that the sample annealed at 300 °C (1.43 eV) has a larger band gap than the other samples. The sample that was annealed at 400 °C has endured defect emissions that are more intense than those of other samples, according to the obtained PL spectra. In addition to these fascinating findings, the samples annealed at 300 °C, 400 °C and 500 °C exhibit a zone of inhibition of 23 mm & 24 mm, 11 mm & 12 mm and 12 mm & 11 mm, respectively for the two tested bacterial strains which authenticate that the 300 °C annealed Sm‐doped CuO nano‐lanceolate deactivates the two pathogenic bacteria more effectively compared to the other samples. As a consequence, the Sm‐doped CuO nano‐lanceolates at 300 °C could potentially be an effective alternative for antibacterial materials, particularly in biomedical applications
Accentuate the positive? Strategic negativity amid the hazard of high expectations
Authors: Parker Owen N. , Short Cole E. , Titus Varkey K. , Gong Ke , Nahm Peter Inho 
Published: April 2024

AbstractResearch SummaryWhile previous organizational impression management (OIM) research focuses on highlighting firms in a favorable light, we explore CEOs' use of “strategic negativity” to manage expectations. We draw on OIM's psychological roots to predict that despite pressure to “be positive,” when CEOs perceive stakeholders are motivated to raise their expectations and have an opportunity to do so, CEOs strategically use negativity to counteract this anticipated expectation increase. We test our predictions on 7330 quarterly earnings calls from 370 publicly traded firms (2008–2019), examining how the “motive” of a positive material earnings surprise and “opportunity” of a new fiscal year jointly increase CEO negativity in prepared remarks. We elaborate the wide applicability of strategic negativity, the “other side” of the OIM phenomenon.Managerial SummaryIn contrast to the prevailing view that CEOs usually “positively spin” the firm's situation to stakeholders, we investigate how CEOs strategically use negativity to counteract stakeholder optimism, provided CEOs perceive expectations are likely to rocket upward. We argue that positive news represents a “motive” and a chance to reflect represents an “opportunity,” and that together they risk raising expectations. Analyzing 7330 quarterly earnings calls of 370 companies (2008–2019), we specifically examined how both (1) a positive earnings surprise and (2) a new fiscal year force CEOs out of their positivity comfort zone and encourage them to be strategically negative in earnings call remarks, to try to lower stakeholder expectations. Our results support this view and pave the way for future research.
HCOO− Doping‐Induced Multiexciton Emissions in Cs3Cu2I5 Crystals for Efficient X‐Ray Scintillation
Authors: Wang Zisheng , Wang Lixiang , Xie Jiahao , Yang Yang , Song Yilong , Xiao Guanjun , Fu Yuhao , Zhang Lijun , Fang Yanjun , Yang Deren , Dong Qingfeng 
Published: April 2024

AbstractSelf‐trapped exciton (STE) luminescence, typically associated with structural deformation of excited states, has attracted significant attention in metal halide materials recently. However, the mechanism of multiexciton STE emissions in certain metal halide crystals remains largely unexplored. This study investigates dual luminescence emissions in HCOO− doped Cs3Cu2I5 single crystals using transient and steady‐state spectroscopy. The dual emissions are attributed to intrinsic STE luminescence originating from the host lattice and extrinsic STE luminescence induced by external dopants, respectively, each of which can be triggered independently at distinct energy levels. Theoretical calculations reveal that multiexciton emission originates from structural distortion of the host and dopant STEs within the 0D lattice in their respective excited states. By meticulously tuning the excitation wavelength and selectively exciting different STEs, the dynamic alteration of color change in Cs3Cu2I5:HCOO− crystals is demonstrated. Ultimately, owing to an extraordinarily high photoluminescence quantum yield (99.01%) and a diminished degree of self‐absorption in Cs3Cu2I5:HCOO− crystals, they exhibit remarkable X‐ray scintillation characteristics with light yield being improved by 5.4 times as compared to that of pristine Cs3Cu2I5 crystals, opening up exciting avenues for achieving low‐dose X‐ray detection and imaging.
Molecular Engineering to Regulate the Pseudo‐Graphitic Structure of Hard Carbon for Superior Sodium Energy Storage
Authors: Zhang Xiang , Hou Zhidong , Jiang Mingwei , Peng Jiahui , Ma Honghao , Gao Yuyang , Wang Jian‐Gan 
Published: April 2024

AbstractResin‐derived hard carbons have shown great advantages in serving as promising anode materials for sodium‐ion batteries due to their flexible microstructure tunability. However, it remains a daunting challenge to rationally regulate the pseudo‐graphitic crystallite and defect of hard carbon toward advanced sodium storage performance. Herein, a molecular engineering strategy is demonstrated to modulate the cross‐linking degree of phenolic resin and thus optimize the microstructure of hard carbon. Remarkably, the resorcinol endows resin with a moderate cross‐linking degree, which can finely tune the pseudo‐graphitic structure with enlarged interlayer spacing and restricted surface defects. As a consequence, the optimal hard carbon delivers a notable reversible capacity of 334.3 mAh g−1 at 0.02 A g−1, a high initial Coulombic efficiency of 82.1%, superior rate performance of 103.7 mAh g−1 at 2 A g−1, and excellent cycling durability over 5000 cycles. Furthermore, kinetic analysis and in situ Raman spectroscopy are performed to reveal the electrochemical advantage and sodium storage mechanism. This study fundamentally sheds light on the molecular design of resin‐based hard carbons to advance sodium energy for scale‐up applications.
High Thermoelectric Performance in Bismuth Telluride via Constructing MoSe2‐2D Heterojunction
Authors: Xiong Tao , He Hailong , Tian Ge , Ren Hongrui , Niu Chunping , Liu Mengmeng , Li Youqun , Wu Yi , Rong Mingzhe 
Published: April 2024

AbstractCurrently, the only thermoelectric (TE) materials commercially available at room temperature are those based on bismuth telluride. However, their widespread application is limited due to their inferior thermoelectric and mechanical properties. In this study, a strategy of growing a rigid second phase of MoSe2 is employed, in situ within the matrix phase to achieve n‐type bismuth telluride‐based materials with exceptional mechanical and thermoelectric properties. The in situ grown second phase contributes to both the electronic and lattice thermal conductivities. This is primarily attributed to the strong energy filtering effect, as the second phase forms a semi‐common lattice interfacial structure with the matrix phase during growth. Furthermore, for composites containing 2 wt% MoSe2, a maximum zT value of 1.24 at 373 K can be achieved. On this basis, 8‐pair TE module is fabricated and 1‐pair TE module is optimized using a homemade p‐type material. The optimized 1‐pair TE module generates a maximum output power of 13.6 µW, which is twice that of the 8‐pair TE module and four times more than the 8‐pair TE module fabricated by commercial material. This work facilitates the development of the TE module by presenting a novel approach to obtaining bismuth telluride‐based thermoelectric materials with superior thermoelectric and mechanical properties.
Copper Ion‐Inspired Dual Controllable Drug Release Hydrogels for Wound Management: Driven by Hydrogen Bonds
Authors: Wang Zhuxian , Liu Jun , Zheng Yixin , Zhang Bohai , Hu Yi , Wu Yufan , Li Yamei , Liu Li , Zhu Hongxia , Liu Qiang , Yang Bin 
Published: April 2024

AbstractBacterial infections and inflammation progression yield huge trouble for the management of serious skin wounds and burns. However, some hydrogel dressing exhibit poor wound‐healing capabilities. Additionally, little information is given on the molecular theory of hydrogel gelation mechanisms and drug release performance from drug‐polymer network in the water environment. Herein, cationic guar gum (CG) is first mixed with dipotassium glycyrrhizinate (DG), and then crosslinked Cu2+ to strengthen the mechanical strength followed by encapsulating mussel adhesive protein (MAP) as composite dressings. Intriguingly, CG‐Cu2+0.5‐DG10 possessed proper rheological properties and mechanical strength predominantly driven by strong CG‐H2O‐Cu2+ and Cu2+‐CG hydrogen bonding interaction. Weak DG‐CG hydrogen bonding only controlled DG release in the initial 4 h, while strong hydrogen bonding is the main force regulating the sustained release of Cu2+ within 48 h. The incorporation of MAP further loosened the tight crosslinking of CG‐Cu2+0.5‐DG10. The screened CG‐Cu2+0.5‐DG10/MAP possessed excellent self‐healing, injectability, antibacterial, anti‐inflammatory, cell proliferation‐promotion activities with high biocompatibility. Therefore, CG‐Cu2+0.5‐DG10/MAP hydrogel expedited wound closure on S. aureus‐infected full‐thickness skin wound model and lowered necrosis progression to the unburned interspaces on a rat burn model. The results highlight the promising translational potential of Cu2+‐inspired hydrogels for the management of burns and infected wounds.
The effect of substance use Certificate‐of‐Need laws on access to substance use disorder treatment facilities
Authors: Shakya Shishir , Bretschneider‐Fries Christine 
Published: April 2024

AbstractWe investigate how substance use Certificate‐of‐Need (CON) laws influence access to substance use disorder treatment facilities in the United States. We use the National Directory of Drug and Alcohol Abuse Treatment Facilities data set, which lists all federal, state, and local government facilities and private facilities that provide substance use treatment services in 2020. Based on the locations of these facilities, we develop a novel access index to substance use disorder treatment facilities that accounts for driving distance and duration to measure the ease of reaching these facilities for individuals living at the population‐weighted county centroids. We find that counties in states with CON laws that border counties without such laws have nearly 10% less spatial accessibility to substance use disorder treatment facilities at a 5% level of significance.
The AUstralian multidomain Approach to Reduce dementia Risk by prOtecting brain health With lifestyle intervention study (AU‐ARROW): A study protocol for a single‐blind, multi‐site, randomized controlled trial
Authors: Gardener Samantha L. , Fuller Stephanie J. , Naismith Sharon L. , Baker Laura , Kivipelto Miia , Villemagne Victor L. , Grieve Stuart M. , Yates Paul , Rainey‐Smith Stephanie R. , Chen Juliana , Thompson Belinda , Armstrong Nicola J. , Fernando Malika G. , Blagojevic Castro Carolina , Meghwar Silochna , Raman Rema , Gleason Andrew , Ireland Catriona , Clarnette Roger , Anstey Kaarin J. , Taddei Kevin , Garg Manohar , Sohrabi Hamid R. , Martins Ralph N. 
Published: April 2024

AbstractINTRODUCTIONThe Finnish Geriatric Intervention Study (FINGER) led to the global dementia risk reduction initiative: World‐Wide FINGERS (WW‐FINGERS). As part of WW‐FINGERS, the Australian AU‐ARROW study mirrors aspects of FINGER, as well as US‐POINTER.METHODAU‐ARROW is a randomized, single‐blind, multisite, 2‐year clinical trial (n = 600; aged 55–79). The multimodal lifestyle intervention group will engage in aerobic exercise, resistance training and stretching, dietary advice to encourage MIND diet adherence, BrainHQ cognitive training, and medical monitoring and health education. The Health Education and Coaching group will receive occasional health education sessions. The primary outcome measure is the change in a global composite cognitive score. Extra value will emanate from blood biomarker analysis, positron emission tomography (PET) imaging, brain magnetic resonance imaging (MRI), and retinal biomarker tests.DISCUSSIONThe finalized AU‐ARROW protocol is expected to allow development of an evidence‐based innovative treatment plan to reduce cognitive decline and dementia risk, and effective transfer of research outcomes into Australian health policy.Highlights
Study protocol for a single‐blind, randomized controlled trial, the AU‐ARROW Study.
The AU‐ARROW Study is a member of the World‐Wide FINGERS (WW‐FINGERS) initiative.
AU‐ARROW's primary outcome measure is change in a global composite cognitive score.
Extra significance from amyloid PET imaging, brain MRI, and retinal biomarker tests.
Leading to development of an innovative treatment plan to reduce cognitive decline.
Children and Adults Explore Human Beings’ Place in Nature and Culture: A Swedish Case-Study of Early Childhood Commons for More Equal and Inclusive Education
Authors: Olsson Liselott Mariett , Lecusay Robert , Nilsson Monica 
Published: April 2024

AbstractThis chapter accounts for a Swedish case-study on the potential of educational commons to promote more equal and inclusive education in the early years. Several conditions decisive for this potential to be activated are identified and analysed: (1) the relation between research and practice, (2) the image of the child, (3) the role of teachers, (4) the definition of the educational task, and (5) the educational methods used. These conditions are described further in terms of how they were activated within a Playworld/Interactive performance based a common research question, shared by preschool children and adults, on human beings’ place in nature and culture. The chapter concludes that educational commons may function as a catalyst in promoting more equal and inclusive education if,

the image of children and teachers is embedded within a shared, intergenerational search for meaning where both children and teachers are conceived as contributing commoners,

education defines its task not only as compensatory but also as complementary and as a place for children’s search for meaning, where imagination, play and the creative co-construction of narratives must be allowed to co-exist with more conventional and “rational” modes of learning and teaching,

methods and theoretical tools in educational practice and research carry an aesthetic variety that incorporates both sensous-perceptive experiences and an enhancement of individual and collective memories as well as opportunities for children and adults to formulate and gather around a common object of knowledge and interest.
Zusammenfassung für Entscheidungstragende
Authors: Erb Karl-Heinz , Tappeiner Ulrike , Jandl Robert , Baumgarten Andreas , Dumke Hartmut , Fischer Tatjana , Formayer Herbert , Gaube Veronika , Getzner Michael , Gingrich Simone , Gratzer Georg , Haas Willi , Hinterberger Friedrich , Jäger Jill , Kottusch Charlotte , Kraxner Florian , Lapin Katharina , Meyer Ina , Schinko Thomas , Shinozaki Kyoko , Schneider Stefan , Schüler Silvio , Stöglehner Gernot , Tasser Erich , Thaler Thomas , Weiss Peter , Wenzel Walter , Zollitsch Werner 
Published: April 2024

ZusammenfassungDie Zusammenfassung für Entscheidungstragende fasst die Inhalte des APCC Special Report „Landnutzung und Klimawandel in Österreich“ in komprimierter Form zusammen. Im Lichte des Zusammenhanges von Landnutzung, Klimawandel und gesellschaftlichem Wohlergehen werden die gegenwärtige Situation und zukünftige Entwicklungen in Österreich synoptisch beschrieben, wesentliche Optionen der Klimawandelanpassung und des Klimaschutzes dargestellt, deren Trade-offs und Synergien systematisch beleuchtet und zentrale Einsichten zur Umsetzung von Strategien zum Klimaschutz und der Klimawandelanpassung in Österreich zusammengefasst.