bluuebunny/crossref_metadata_2025_split huggingface dataset:
Micromapping testicular sperm extraction: A new technique for microscopic testicular sperm extraction in nonobstructive azoospermia
Authors: Tai Toshihiro , Miyamoto Wakaba , Fukuoka Yuriko , Shibasaki Sena , Takahashi Mizuho , Okuyama Noriyuki , Hattori Hiromitsu , Ishikawa Ikue , Nagaura Satoko , Yoshinaga Koki , Koizumi Masae , Hashimoto Tomoko , Toya Mayumi , Kumagai Jin , Igarashi Hideki , Kyono Koichi 
Published: March 2024

AbstractPurposeIn microscopic testicular sperm extraction (mTESE) for nonobstructive azoospermia (NOA), sperm can be recovered relatively easily in some cases, and mTESE may be retrospectively considered excessive. However, mTESE is routinely performed in the majority of NOA patients because of the difficulty in predicting tissue status. A minimally invasive and comprehensive sperm retrieval method that allows on‐the‐spot tissue assessment is needed. We have developed and evaluated a novel sperm retrieval technique for NOA called micromapping testicular sperm extraction (MMTSE).MethodsMMTSE involves dividing the testis into four sections and making multiple small needle holes in the tunica albuginea to extract seminiferous tubules and retrieve sperm. The sperm‐positive group by MMTSE (Group I) underwent additional tissue collection (ATC) via a small incision, whereas the sperm‐negative group by MMTSE (Group 0) underwent mTESE.ResultsIn total, 40 NOA participants underwent MMTSE. Group I included 15 patients and Group 0 included 25 patients. In Group 1, sperm were recovered from all patients by ATC. In Group 0, sperm were recovered in 4 of 25 cases using mTESE.ConclusionsMMTSE shows promise as a simple method that comprehensively searches testicular tissue and retrieves sperm using an appropriate method while minimizing patient burden.
Self‐Limited Formation of Cobalt Nanoparticles for Spontaneous Hydrogen Production through Hydrazine Electrooxidation
Authors: Liu Qian , Tan Xin , Liao Xiaobin , Lv Jiabao , Li Xiaotong , Chen Zerui , Yang Yue , Wu Angjian , Zhao Yan , Wu Hao Bin 
Published: March 2024

AbstractHydrogen (H2) has emerged as a highly promising energy carrier owing to its remarkable energy density and carbon emission‐free properties. However, the widespread application of H2 fuel has been limited by the difficulty of storage. In this work, spontaneous electrochemical hydrogen production is demonstrated using hydrazine (N2H4) as a liquid hydrogen storage medium and enabled by a highly active Co catalyst for hydrazine electrooxidation reaction (HzOR). The HzOR electrocatalyst is developed by a self‐limited growth of Co nanoparticles from a Co‐based zeolitic imidazolate framework (ZIF), exhibiting abundant defective surface atoms as active sites for HzOR. Notably, these self‐limited Co nanoparticles exhibit remarkable HzOR activity with a negative working potential of −0.1 V (at 10 mA cm−2) in 0.1 m N2H4/1 m KOH electrolyte. Density functional theory (DFT) calculations are employed to validate the superior performance of low‐coordinated Co active sites in facilitating HzOR. By taking advantage of the potential difference between HzOR and the hydrogen evolution reaction (HER), a novel HzOR||HER electrochemical system is developed to spontaneously produce H2 without external energy input. Overall, the work offers valuable guidance for developing active HzOR catalyst. The novel HzOR||HER electrochemical system represents a promising and innovative solution for energy‐efficient hydrogen production.
Modulating the d‐Band Center of RuO2 via Ni Incorporation for Efficient and Durable Li–O2 batteries
Authors: Sun Chaoyang , Cui Xinhang , Xiao Fenglong , Cui Deliang , Wang Qilong , Dang Feng , Yu Haohai , Lian Gang 
Published: March 2024

AbstractRechargeable Li–O2 batteries (LOBs) are considered as one of the most promising candidates for new‐generation energy storage devices. One of major impediments is the poor cycle stability derived from the sluggish reaction kinetics of unreliable cathode catalysts, hindering the commercial application of LOBs. Therefore, the rational design of efficient and durable catalysts is critical for LOBs. Optimizing surface electron structure via the negative shift of the d‐band center offers a reasonable descriptor for enhancing the electrocatalytic activity. In this study, the construction of Ni‐incorporating RuO2 porous nanospheres is proposed as the cathode catalyst to demonstrate the hypothesis. Density functional theory calculations reveal that the introduction of Ni atoms can effectively modulate the surface electron structure of RuO2 and the adsorption capacities of oxygen‐containing intermediates, accelerating charge transfer between them and optimizing the growth pathway of discharge products. Resultantly, the LOBs exhibit a large discharge specific capacity of 19658 mA h g−1 at 200 mA g−1 and extraordinary cycle life of 791 cycles. This study confers the concept of d‐band center modulation for efficient and durable cathode catalysts of LOBs.
Reporting outcome measures in veterinary physiotherapy with particular reference to the treatment of canine and equine joint cases in the UK
Authors: Brookes William , Payne Richard , Lea Richard 
Published: March 2024

AbstractBackgroundOutcome measures are extensively used within human physiotherapy, but a widely accepted issue in veterinary physiotherapy is that outcome measures lack sufficient evaluation and standardisation in terms of how they are implemented. This cross‐sectional study aimed to provide clarity on (1) the current selection of outcome measures in canine and equine physiotherapy and (2) investigate external influences on outcome measure selection, including comparative literature availability, professional memberships and background.MethodsA structured scoping literature review consolidated current understanding and limitations. This informed a survey of qualified veterinary physiotherapists (n = 40). The statistical analysis comprised descriptive statistics.ResultsKey observations included (1) a lack of difference in outcome measure application between veterinary physiotherapists with and without a human physiotherapy background, (2) enhanced outcome measure utilisation by registry body members and (3) an overall skew towards subjective, rather than objective, outcome measure use.LimitationsThe study was limited by the absence of a defined veterinary physiotherapist population and subsequent convenience sample size.ConclusionThe apparent skew towards subjective outcome measures highlights objective outcome measure underutilisation and the need for a more extensive evidence base. In conclusion, there is a need to develop comprehensive professional development resources promoting the use of repeatable outcome measures such as goniometers and the Liverpool osteoarthritis scoring.
Exploring the sociocultural experiences of student veterinary nurses in the clinical learning environment through the lens of situated learning theory
Authors: Holt Susan L. , Mason Jenny , Farrell Mary , Corrigan Richard H. , Warman Sheena 
Published: March 2024

AbstractBackgroundStudent veterinary nurses (SVNs) complete significant time in clinical placements and this training can have a positive or negative impact on the development of professional skills and identity.MethodsA cross‐sectional design, using semi‐structured interviews, explored 12 SVNs' experiences of clinical placements. Interpretative phenomenological analysis was used to explore each individual participant's experience, prior to the identification of themes across participants' experiences.ResultsMost students reported a sense of belonging within the practice team, which fostered engagement. Clinical supervisors were considered key role models and vital support for student progress. Students reported conflict between the demands of the practice and the requirements of their student status. Some poor interpersonal interactions led to reduced confidence.LimitationsThe results may not reflect experiences of the diversity of student demographics, such as those students with protected characteristics, as described in the Equality Act 2010, who may encounter specific workplace challenges.ConclusionTo ensure parity and positive experiences, accredited educational institutes can plan regular engagement with student feedback and support of the training practice. Training practice teams can ensure they are meeting the student's needs and fostering a positive learning environment by adhering to the RCVS Framework for Veterinary Nurse Education and Training, which will, in turn, benefit the whole team. Clinical supervisors can play a convening role in increasing belonging and participation within the clinical learning environment.
Extraction and structural determination of pectin from pumkin Cucurbita moschata
Authors: Thuy Thanh Thi Thu , Bien Do Thi , Thu Quach Thi Minh , Xuan Do Thi Thanh , Van Nguyen Bui , Van Quang Ngo , Cuong Ho Duc 
Published: March 2024

AbstractPectin is a heterogeneous complex polysaccharide found in the primary cell wall of most cells. In this work, low‐methoxyl pectin was extracted from pumpkin (Cucurbita moschata). The obtained pectin was characterized by GPC FTIR and NMR spectra. The obtain results showed that structural feature of the pectin is a main chain of poly‐α(1→4)‐D‐galacturonic acid and occasionally interrupted by α(1→2)‐linked α‐L‐rhamnopyranose residues and branches Galp is linked to GalpA at C‐2 position.
Physicochemical character of fresh and black garlic: 12‐day thermal aged process
Authors: Quan Nguyen Xuan Hong , Nga Vo Thi , Nhi Dinh Nu Kieu , Duong Ngo Thi Thuy , Vinh Huynh Ngoc , Phung Nguyen Kim Phi , Thu Nguyen Thi Hoai 
Published: March 2024

AbstractGarlic has long been known possessing many benefits for health and used as a pivotal spice for daily meals in many countries. Recent studies showed that black garlic has many advantages such as no strong odor and still remaining bioactivities of fresh ones, even better. Commercial black garlic products in Vietnam have not showed the physicochemical analysis as well as the original source. This study concentrated on Allium sativum L. garlic bulds collected at Ninh Thuan province, an area of which garlic is one of main agricultural products. The essential oil of the fresh garlic was analyzed by GC‐MS. From the fresh garlic bulds, two compounds, uracil (1) and butyl 4‐hydroxybenzoate (2) were isolated and structurally determined. Fresh garlic bulds were then prepared to black garlic. The physicochemical analysis methods showed that the S‐allyl cysteine, reducing sugar, total polyphenol and total protein content of 12‐day black garlic were much higher than those of fresh one. For instance, the S‐allyl cysteine content in fresh garlic and black one were 53.2 and 663.6 μg/g, the reducing sugar were 9.73 and 36.51 g/100g, respectively.
Comprehensive separation and identification of chemical constituents from Abelmoschus manihot (L.) medic by polyamide chromatography coupled with high‐performance counter‐current chromatography and preparative liquid chromatography
Authors: Fan Chen , Li Nai , Cao Xueli 
Published: March 2024

AbstractThree methods (polyamide chromatography coupled with high‐performance counter‐current chromatography (HPCCC) and preparative liquid chromatography) were used to detection and separation of flavonoids from Abelmoschus manihot (L.) Medic. For HPLC analysis, there are main six substances in Abelmoschus manihot (L.) Medic. After polyamide chromatography, the main flavonoids existed in fractions eluted between 50 and 90 % aqueous ethanol. Among these, four fractions of interest from column were separated by HPCCC with the different solvent system. And other two fractions were separated by preparative liquid chromatography. Six high‐purity flavonoids were obtained eventually and identified by MS, 1H and 13C NMR: rutin (1), hyperoside (2), isoquercitrin (3), avicularin (4), quercetin (5), amentoflavone (6). In addition, the substances 4 and 6 for the first time were isolated from Abelmoschus manihot (L.) Medic by HPCCC.
Chemical constituents of Peltophorum pterocarpum stems
Authors: Cham Ba Thi , Linh Nguyen Thi Thuy , Anh Nguyen Thi Hoang , Quan Tran Duc , Tam Nguyen Thanh , Thien Dao Duc , Nhung Le Thi Hong , Van Sung Tran , Son Ninh The , Delfino Domenico V. , Hoang Vu Dinh , Thuy Trinh Thi 
Published: March 2024

AbstractA phytochemical study of the ethyl acetate extract (EtOAc) of Peltophorum pterocarpum stems, collecting from Ha Noi city, Vietnam, has resulted in the isolation and determination of six compounds, including bergenin (1), cinchonain Ia (2), lupeol (3), betulinic acid (4), gallic acid (5), and pyrogallic acid (6). The chemical structures of these compounds were characterized by NMR‐spectra, and MS data. Compounds 2 and 6 were found in the genus Peltophorum for the first time.
Assay of Retinol and α‐tocopherol involving Ce(IV)‐Ce(III) Redox Couple Spectrophotometrically
Authors: Kumar Ashwani , Kamboj Mamta 
Published: March 2024

AbstractThe present procedure aims to develop an affordable, prompt, and consistent spectrophotometric approach for the assay of Retinol and α‐tocopherol in pharmaceutical formulations and distinct edibles. The present procedure based upon the reduction of Ce(IV) into Ce(III) by the working vitamins retinol and α‐tocopherol, the reduced Ce(III) formed a blue colored complex with reagent arsenazo(III) in between the range of pH 3.0‐3.3. The optimization of analytical variables was done carefully. The maximum absorption obtained at 648 nm with molar absorptivity 1.5×104 L mol‐1cm‐1 and 0.75×104 L mol‐1 cm‐1 for Retinol and α‐tocopherol respectively. Beer's law is obeyed within the range of concentrations 0.5‐6.0 μg mL‐1 for Retinol and 0.4‐25.0 μg mL‐1 for α‐tocopherol. The limit of detection (LOD) was 0.3 μg mL‐1 for Retinol and 0.1 μg mL‐1 for α‐tocopherol and the limit of quantification (LOQ) was 0.9 μg mL‐1for Retinol and 0.3 μg mL‐1 for α‐tocopherol. The decision limit (CCα) was 0.8 μg kg‐1 and 5.2 μg kg‐1 and the detection capability (CCβ) values were 1.4 μg kg‐1 and 9.0 μg kg‐1 for Retinol and α‐tocopherol respectively. Distinct Edibles were quantified using the proposed method, and the results obtained are in good agreement with the existing methods.
Essential oils of Tunisian Pinus radiata D. Don, chemical composition and study of their herbicidal activity
Authors: Ismail Amri , Habiba Kouki , Yassine Mabrouk , Mohsen Hanana , Bassem Jamoussi , Lamia Hamrouni 
Published: March 2024

AbstractLittle is known about the phytotoxic effects of essential oils from Pine species, GC and GC/MS analysis of Pinus radiata D. Don essential oil obtained from needles, resulted in the identification of 49 components comprising 97.6 % of the oil totality. The composition was l dominated by monoterpene hydrocarbons (86.4 %) with β‐pinene (40.2 %), limonene (25.5 %) and α‐pinene (15.2 %) were the major compounds. On the herbicidal activity, the oil strongly inhibited seed germination and seedling growth of all tested weeds in a dose dependent manner with the effect being significantly more effective on dicots (Sinapis arvensis L. and Trifolium campestre Schreb) than monocots (Phalaris canariensis L.).
Highly efficient transfer hydrogenation of carbonyl compounds over supported nickel and palladium nanoparticles
Authors: Thien Co Thanh , Minh Nguyen Nhut , Khang Vo Ly Dinh 
Published: March 2024

AbstractIn this work, metal nanoparticles were successfully synthesized through the reduction of metal salts using reducing agents such as: ethylene glycol (EG) and sodium borohydride (NaBH4). These metal nanoparticles were impregnated into the supports M‐X (M = Ni, Pd; X = Bent, C, Zeolite, and Al2O3) in high yield. The physio‐chemical properties of these catalysts were characterized by various techniques such as UV‐Vis spectroscopy, powder X‐ray diffraction (PXRD), Transmission electron microscopy (TEM) and the specific surface area of M‐X was evaluated by N2 adsorption isotherm analysis at 77 K. All results corroborated the loading process. Literally, TEM images indicated that the palladium and nickel nanoparticles size are 6 and 13 nm, respectively. The efficiency of these catalysts was performed on the transfer hydrogenation of various carbonyl substrates in the presence of potassium hydroxide at atmosphere pressure. The results showed that both nickel and palladium supported X catalysts exhibited high activities over 99 % within 60 min in the presence of potassium hydroxide.
Synthesis, characterization and anticancer properties of platinum(II) complexes bearing chiral azomethine ligands
Authors: Trung Nguyen Quang , Nam Pham Thi Phuong , Van Tuyen Nguyen 
Published: March 2024

AbstractPt(II) complexes bearing one N‐salicylidene‐(S)‐1‐phenylethylamine [HL(S)] or N‐salicylidene‐(R)‐1‐phenylethylamine [HL(R)] were synthesized and characterized by electrospray ionization mass spectroscopy (ESI‐MS), Fourier‐transform infrared (FT‐IR), nuclear magnetic resonance (NMR) and circular dichroism (CD) spectroscopies. The results of the micro‐analytic and spectroscopic methods disclosed that the reaction of K2PtCl4 with the chiral azomethine ligand in DMSO produced both trans‐ and cis‐[Pt(II)L(DMSO)Cl]. Then only trans‐[Pt(II)L(DMSO)Cl] isomers in Na2CO3 solution can transform to Pt(II) complexes 3 in coordination of the ligands to platinum as tridentate C,N,O‐donors. The photophysical properties of obtained platinum(II) complexes were studied by UV‐visible and luminescent spectra. The results showed that they all exhibited emission in the visible region. Anticancer properties in vitro of obtained Pt(II) complexes were scaned for KB and HepG‐2 cancer cell lines. They had good activity for the tested cancer cells. The cis‐Pt(II) complexes possessed higher anticancer activity than trans‐Pt(II) complexes and R‐enantiomers were found to be more cytotoxic than S‐enantiomers.
Preparation and study on the properties of acrylonitrile butadiene styrene/polyphenylene oxide polymer blend
Authors: Trung Tran Huu , Huynh Mai Duc , Cong Do Van , Thai Nguyen Thi , Tham Do Quang , Nguyen  , Dat Huu , Dung Trinh Quang , Hai Luong Như , Giang Nguyen Vu 
Published: March 2024

AbstractBlends of polyphenylene oxide (PPO) and acrylonitrile butadiene styrene (ABS) were prepared by melt‐mixing method. Flammability of these blends was studied by using UL‐94 (plastics flammability standard) and LOI (limited oxygen index) tests. The results showed the role of PPO as flame retardant in the blends which can inhibit the burning process. All blends of PPO and ABS were graded as V‐1 and LOI values were higher than 21. As a physical mixture, tensile strength of PPO/ABS blends maintained values between the tensile of neat ABS and PPO. Melting rheology characterization of samples showed that the fabrication of PPO/ABS blend consumed less energy than that of PPO polymer. Differential scanning calorimetry analysis investigated that PPO and ABS were partially miscible in blend with two glass transition temperatures (Tg) which ranged between Tg of ABS and PPO.
Modified bis‐tetrahydrofuran inhibitors toward improved binding to HIV‐1 proteases
Authors: Paulin John P. , Franco Francisco C. 
Published: March 2024

AbstractHIV treatment includes inhibiting HIV‐1 protease which is responsible for viral maturation. However, HIV‐1 protease responds to drug treatment by mutation making the protease‐resistant to inhibitors. In this study, binding interactions between bis‐tetrahydrofuran‐derived (bis‐THF) inhibitors and HIV‐1 protease were described by molecular docking. We characterized the binding energies and all the amino acids present during the binding of the bis‐THF derivatives to the wild type HIV‐1 protease and several mutant HIV‐1 proteases. We found that the modifications to the structure of darunavir helped improve its binding to the wild‐type protease. Also, these structures were found to interact with the mutant HIV‐1 proteases better than darunavir. Results showed that compound 4 had the highest binding energy to the wild‐type HIV‐1 protease and the V654/84 mutant, while compound 5 was found to interact greatly with cyclic urea‐based inhibitor‐resistant proteases and the multi‐protease inhibitor‐resistant HIV‐1 protease. The results may help explain how structural modifications to bis‐tetrahydrofuran inhibitors affect their response to wild‐type and resistant HIV‐1 proteases. Furthermore, this study is the first demonstration of the differences in the amino acids interacting with protease inhibitors for wild‐type and mutated HIV‐1 proteases and may help in the design of bis‐THF derivatives as HIV‐1 protease inhibitors.
Electrochemical study on the structure of PbO2 in mixed gel electrolytes during cycling by cyclic voltammetry
Authors: Binh Phan Thi , Van Anh Nguyen Thi , Thuy Mai Thi Thanh , Xuan Mai Thi , Duyen Nguyen The 
Published: March 2024

AbstractPb/PbO2 electrodes are made by anodizing method from H2SO4 solution (1.26 g/cm3). The mixed gel electrolyte was prepared by mixing H2SO4 (1.37 g/cm3) with liquid glass (LG) in the presence of polyacrylamide (PAM), propylene glycol (PPG), and nano fumed silica (NFS). After finishing 150 cycles by cyclic voltammetry (CV) in different electrolytes at a scan rate of 100 mV/s, the structure of PbO2, including morphology and the content of elements, were analysed by scanning electron microscopy (SEM) and energy dispersion spectroscopy (EDS), respectively, as well as by CV diagrams. There was found a huge difference in both the grain size and surface structure of PbO2 electrodes. Among them, the morphology of PbO2 electrode after cycling in mixed gel electrolyte using PAM with NFS is similar to that obtaining from H2SO4 solution (1.26 g/cm3). The appearance of α‐ and β‐PbO2 forms depends on the combination of gelling agents. The existence of α‐PbO2 form was found only by using separate PAM or PAM with PPG leading to small discharge densities, while both α‐ and β‐PbO2 forms were clearly observed by combining PAM with NFS. The height of redox peak in this case is approximately the same as that in sulfuric acid solution.
Modeling of titania slag carbochlorination
Authors: Hai Tran Duy , Khoa Tran Anh , Vien Le Minh , Tuan Phan Dinh 
Published: March 2024

AbstractTitanium tetrachloride, a product of titanium slag chlorination in the presence of carbon, is an intermediate product for high grade TiO2 pigment preparation and titanium metallurgy. The chlorination of carbon‐titanium dioxide pellets with gas mixtures of N2 and Cl2 was studied at high temperatures (750‐1050 oC) and various partial pressures of chlorine (0.1‐0.8 atm) in a fixed‐bed reactor with the inner diameter of 80 mm. Based on the comparison of experimental and computational studies, a principal mechanism of the TiO2 carbochlorination was proposed, and chlorine concentration profile at different reaction conditions was clearly understandable. Porous diffusion of chlorine inside the C‐TiO2 pellet structure played an important role in the kinetic reaction model.
N‐Formylation of amines using a domestic microwave oven and bioactivities of some N‐formamides
Authors: Mai Nguyen Thi Ngoc , Van Dat Nguyen , Huan Trinh Thi , Hoan Duong Quoc 
Published: March 2024

AbstractA reasonable and chemoselective approach for N‐formylation of various amines with N,N‐dimethylformamide in presence of acetic acid has been improved under irradiation of a domestic microwave oven. The method was found to be compatible with primary, secondary, aromatic and aliphatic amines with electron withdrawing and electron donating groups as well but did not support to form N‐formate derivatives. N‐formamides 1, 2, and 3 did not exhibit antibacterial activity on Gram(+), Gram(‐) and fungi but compounds 1, 2, 18 and 19 showed weak antioxidant activity with SC: 36.8 %, 38.3 %, 45.7 %, respectively. Compound 18 exhibited antioxidant activity with SC50: 47.2 μg/mL.