bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Galactic Disk-Halo Transition – Evidence from Stellar Abundances
Authors: Nissen Poul Erik , Schuster William J. 
Published: March 2009

AbstractNew information on the relations between the Galactic disks, the halo, and satellite galaxies is being obtained from elemental abundances of stars having metallicities in the range −1.5 < [Fe/H] < −0.5. The first results for a sample of 26 halo stars and 13 thick-disk stars observed with the ESO VLT/UVES spectrograph are presented. The halo stars fall in two distinct groups: one group (9 stars) has [α/Fe] = 0.30 ± 0.03 like the thick-disk stars. The other group (17 stars) shows a clearly deviating trend ranging from [α/Fe] = 0.20 at [Fe/H] = −1.3 to [α/Fe] = 0.08 at [Fe/H] = −0.8. The kinematics of the stars are discussed and the abundance ratios Na/Fe, Ni/Fe, Cu/Fe and Ba/Y are applied to see if the “low-alpha” stars are connected to the thin disk or to Milky Way satellite galaxies. Furthermore, we compare our data with simulations of chemical abundance distributions in hierarchically formed stellar halos in a ΛCDM Universe.
Mapping low-latitude stellar substructure with SEGUE photometry
Authors: de Jong Jelte T. A. , Yanny Brian , Rix Hans-Walter , Bell Eric F. , Dolphin Andrew E. 
Published: March 2009

AbstractEncircling the Milky Way at low latitudes, the Low Latitude Stream is a large stellar structure, the origin of which is as yet unknown. As part of the SEGUE survey, several photometric scans have been obtained that cross the Galactic plane, spread over a longitude range of 50° to 203°. These data allow a systematic study of the structure of the Galaxy at low latitudes, where the Low Latitude Stream resides. We apply colour-magnitude diagram fitting techniques to map the stellar (sub)structure in these regions, enabling the detection of overdensities with respect to smooth models. These detections can be used to distinguish between different models of the Low Latitude Stream, and help to shed light on the nature of the system.
The Bulge-disc connection in the Milky Way
Authors: Binney James 
Published: March 2009

AbstractBulges come in two flavours – classical and pseudo. The principal characteristics of each flavour are summarised and their impact on discs is considered. Classical bulges probably inhibit the formation of stellar discs. Pseudobulges exchange angular momentum with stars and gas in their companion discs, and also with its embedding dark halo. Since the structure of a pseudobulge depends critically on its angular momentum, these exchanges are expected to modify the bulge. The consequences of this modification are not yet satisfactorily understood. The Galaxy has a pseudobulge. I review the manifestations of its interaction with the disc. More work is needed on the dynamics of gas near the bulge's corotation radius, and on tracing the stellar population in the inner few hundred parsecs of the Galaxy.
Stellar abundances tracing the formation of the Galactic Bulge
Authors: Barbuy Beatriz , Zoccali Manuela , Ortolani Sergio , Hill Vanessa , Renzini Alvio , Meléndez Jorge , Gómez Anita , Asplund Martin , Minniti Dante , Bica Eduardo , Alves-Brito Alan 
Published: March 2009

AbstractThe metallicity distribution and abundance ratios of the Galactic bulge are reviewed. Issues raised by different groups in recent work, in particular the high metallicity end, a comparison between the oxygen abundances derived from different indicators, the [OI] 630nm and IR OH lines, and the issue of measuring giants vs. dwarfs, are discussed. Finally, abundances in bulge globular clusters are briefly described.
The influence of star clusters on galactic disks: new insights in star-formation in galaxies
Authors: Kroupa Pavel 
Published: March 2009

AbstractStars form in embedded star clusters which play a key role in determining the properties of a galaxy's stellar population. A large fraction of newly born massive stars are shot out from dynamically unstable embedded-cluster cores spreading them to large distances before they explode. Embedded clusters blow out their gas once the feedback energy from the new stellar population overcomes its binding energy, leading to cluster expansion and in many cases dissolution into the galaxy. Galactic disks may be thickened by such processes, and some thick disks may be the result of an early epoch of vigorous star-formation. Binary stellar systems are disrupted in clusters leading to a lower fraction of binaries in the field, while long-lived clusters harden degenerate-stellar binaries such that the SNIa rate may increase by orders of magnitude in those galaxies that were able to form long-lived clusters. The stellar initial mass function of the whole galaxy must be computed by adding the IMFs in the individual clusters. The resulting integrated galactic initial mass function (IGIMF) is top-light for SFRs < 10M⊙/yr, and its slope and, more importantly, its upper stellar mass limit depend on the star-formation rate (SFR), explaining naturally the mass–metallicity relation of galaxies. Based on the IGIMF theory, the re-calibrated Hα-luminosity–SFR relation implies dwarf irregular galaxies to have the same gas-depletion time-scale as major disk galaxies, implying a major change of our concept of dwarf-galaxy evolution. A galaxy transforms about 0.3 per cent of its neutral gas mass every 10 Myr into stars. The IGIMF-theory also naturally leads to the observed radial Hα cutoff in disk galaxies without a radial star-formation cutoff. It emerges that the thorough understanding of the physics and distribution of star clusters may be leading to a major paradigm shift in our understanding of galaxy evolution.
Measuring Outer Disk Warps with Optical Spectroscopy
Authors: Christlein Daniel , Bland-Hawthorn Joss 
Published: March 2009

AbstractWarps in the outer gaseous disks of galaxies are a ubiquitous phenomenon, but it is still unclear what generates them. One theory is that warps are generated internally through spontaneous bending instabilities. Other theories suggest that they result from the interaction of the outer disk with accreting extragalactic material. In this case, we expect to find cases where the circular velocity of the warp gas is poorly correlated with the rotational velocity of the galaxy disk at the same radius. Optical spectroscopy presents itself as an interesting alternative to 21-cm observations for testing this prediction, because (i) separating the kinematics of the warp from those of the disk requires a spatial resolution that is higher than what is achieved at 21 cm at low HI column density; (ii) optical spectroscopy also provides important information on star formation rates, gas excitation, and chemical abundances, which provide clues to the origin of the gas in warps. We present here preliminary results of a study of the kinematics of gas in the outer-disk warps of seven edge-on galaxies, using multi-hour VLT/FORS2 spectroscopy.
HI in Galactic Disks
Authors: Brinks Elias , Bigiel Frank , Leroy Adam , Walter Fabian , de Blok W. J. G. , Bagetakos Ioannis , Usero Antonio , Kennicutt Robert C. 
Published: March 2009

AbstractStudies of the atomic phase of the interstellar medium, via the 21–cm spectral line of neutral hydrogen (H I), play a key rôle in our attempts to understand the structure and evolution of disk galaxies. We present here results from The H I Nearby Galaxy Survey (THINGS) and focus on the mass distribution as derived from the observed kinematics, and on the link between gas and star formation rate surface density, i.e., the Schmidt–Kennicutt law. Also, we briefly dwell on the wealth and wide variety of structures, often outlining what seem to be expanding shells surrounding sites of recent, massive star formation.
Disk Stability and Turbulence Generation: Effects of the Stellar Component
Authors: Kim Woong-Tae 
Published: March 2009

AbstractGalactic disks consist of both stars and gas. The stars gravitationally influence the gas either in disks at large or within spiral arms, leading to the formation of giant clouds and turbulence driving in the gas. In featureless disks as in flocculent galaxies, swing amplification operating in a combined star-gas disk is efficient to form bound condensations and feed a significant level of random gas motions. This occurs when the gaseous Toomre parameter is less than 1.4 for the stellar parameters similar to the solar neighbourhood conditions. In disks with spiral features, on the other hand, spiral-arm spurs and associated giant clouds develop as a consequence of magneto-Jeans instability in which magnetic tension counterbalances the stabilizing Coriolis force. Spiral shocks are inherently unstable when the vertical dimension is taken into account, exhibiting flapping motions of the shock front. This naturally converts the kinetic energy in galaxy rotation into random kinetic energy of the gas. The resulting turbulent motions are supersonic and persist despite strong shock dissipation. Thermal instability occurring in gas flows across spiral arms prompts phases transitions that produce a significant fraction of thermally-unstable, intermediate-temperature gas in the postshock expansion zones.
Halo chemistry and first stars. The chemical composition of the matter in the early Galaxy, from C to Mg
Authors: Spite M. , Bonifacio P. , Cayrel R. , Spite F. , Francois P. , Ludwig H. G. , Caffau E. , Andrievsky S. , Barbuy B. , Plez B. , Molaro P. , Andersen J. , Beers T. , Depagne E. , Nordström B. , Primas F. 
Published: March 2009

AbstractFrom NLTE computations of the magnesium abundance in a sample of extremely metal-poor giants we derive [Mg/Fe]=+0.7, leading to [Al/Mg]=−0.80 and [Na/Mg]=−0.85 in the early Galaxy. The ratio [O/Mg] should be near to the solar value. Measurements of nitrogen abundances derived from the analysis of the NH band in eight more stars confirm the large scatter of the ratios [N/Fe] and [N/O] in the early Galaxy.
Numerical simulations of galaxy evolution in cosmological context
Authors: Martig Marie , Bournaud Frédéric , Teyssier Romain 
Published: March 2009

AbstractLarge volume cosmological simulations succeed in reproducing the large-scale structure of the Universe. However, they lack resolution and may not take into account all relevant physical processes to test if the detail properties of galaxies can be explained by the CDM paradigm. On the other hand, galaxy-scale simulations could resolve this in a robust way but do not usually include a realistic cosmological context.To study galaxy evolution in cosmological context, we use a new method that consists in coupling cosmological simulations and galactic scale simulations. For this, we record merger and gas accretion histories from cosmological simulations and re-simulate at very high resolution the evolution of baryons and dark matter within the virial radius of a target galaxy. This allows us for example to better take into account gas evolution and associated star formation, to finely study the internal evolution of galaxies and their disks in a realistic cosmological context.We aim at obtaining a statistical view on galaxy evolution from z ≃ 2 to 0, and we present here the first results of the study: we mainly stress the importance of taking into account gas accretion along filaments to understand galaxy evolution.
A Roadmap for Delivering the Promise of Gaia
Authors: Prusti T. , Aerts C. , Grebel E. K. , Jordi C. , Klioner S. A. , Lindegren L. , Mignard F. , Randich S. , Walton N. A. 
Published: March 2009

AbstractGaia development is in full speed aiming to the launch in December 2011. While the entities formally responsible to make Gaia happen are very focused to be ready in time, it is necessary to explore the readiness of the wider scientific community to exploit Gaia data in the future. The GST sees a role for itself in building and enabling the community to use the Gaia catalogues when they become available. This paper gives the background for the current activities the GST is taking to promote the community to start preparations for the exploitation of Gaia data.
Treatment of Iron Deficiency Anemia in Orthopedic Surgery with Intravenous Iron: Efficacy and Limits
Authors: Theusinger Oliver M. , Leyvraz Pierre-François , Schanz Urs , Seifert Burkhardt , Spahn Donat R. 
Published: March 2009

Background
Preoperative anemia is frequent in patients undergoing orthopedic surgery. The purpose of this study was to assess the preoperative increase of hemoglobin in iron deficiency anemia patients treated with intravenous iron.

Methods
After obtaining written informed consent, 20 patients with iron deficiency anemia received 900 mg intravenous iron sucrose over 10 days starting 4 weeks before surgery. Changes of hemoglobin and iron status were measured over 4 weeks and at discharge. In the last 11 patients, endogenous erythropoietin was also measured. Data were analyzed using the Friedman test followed by pairwise Wilcoxon signed rank tests with Bonferroni correction.

Results
Hemoglobin increased significantly (P < 0.0001) after intravenous iron treatment. Overall, the mean maximum increase was 1.0 +/- 0.6 g/dl (range, 0.2-2.2 g/dl). Ferritin increased from 78 +/- 70 to 428 +/- 191 microg/l (P = 0.0001), ferritin index decreased from 2.7 +/- 2.4 to 1.5 +/- 1.0 (P = 0.0001), and soluble transferrin receptor decreased from 4.1 +/- 2.3 mg/l to 3.7 +/- 2.3 mg/l (P = 0.049), whereas transferrin saturation (20.5 +/- 9.0 to 22.9 +/- 9.0%) and serum iron (13.3 +/- 4.6 to 13.1 +/- 4.5 microm) did not change significantly after intravenous iron treatment. Endogenous erythropoietin decreased from 261 +/- 130 pg/ml to 190 +/- 49 pg/ml 2 weeks after intravenous iron treatment (P = 0.050, not significant after Bonferroni correction). No adverse events related to intravenous iron were observed. The maximum increase of hemoglobin was observed 2 weeks after the start of intravenous iron treatment, indicating that administration of intravenous iron 2-3 weeks before surgery may be optimal.

Conclusion
Treatment with intravenous iron allows correcting iron deficiency anemia before elective surgery.
Burst Activation of the Cerebral Cortex by Flash Stimuli during Isoflurane Anesthesia in Rats
Authors: Hudetz Anthony G. , Imas Olga A. 
Published: March 2009

Background
The degree of suppression of sensory functions during general anesthesia is controversial. Here, the authors investigated whether discrete flash stimuli induced cortical field potential responses at an isoflurane concentration producing burst suppression and compared the spatiotemporal properties and frequency spectra of flash-induced burst responses with those occurring spontaneously.

Methods
Rats were equipped with multiple epidural and intracortical electrodes to record cortical field potentials in the right hemisphere at several locations along the anterior-posterior axis. At isoflurane concentrations of 1.1, 1.4, and 1.8%, discrete light flashes were delivered to the left eye while cortical field potentials were continuously recorded.

Results
Isoflurane at 1.4-1.8% produced burst suppression. Each flash produced a visual evoked potential in the primary visual cortex followed by secondary bursting activity in more anterior regions. The average latency and duration of these bursts were 220 and 810 ms, respectively. The spontaneous and flash-induced bursts were similar in frequency, duration, and spatial distribution. They had maximum power in the frontal (primary motor) cortex with a dominant frequency of 10 Hz.

Conclusions
The results suggest that discrete flash stimuli activate the motor regions of the cerebral cortex during isoflurane anesthesia and that these activations are analogous with those that occur spontaneously during burst suppression. Electrocortical suppression of the cortex during anesthesia does not prevent its response to visual stimuli.
Midazolam Potentiates Nociceptive Behavior, Sensitizes Cutaneous Reflexes, and Is Devoid of Sedative Action in Neonatal Rats
Authors: Koch Stephanie C. , Fitzgerald Maria , Hathway Gareth J. 
Published: March 2009

Background
The significant postnatal maturation of gamma-aminobutyric acid signaling in the developing brain is likely to have important implications for infant pain processing. Gamma-aminobutyric acid receptor activation evokes analgesia and sedation in the adult, but the impact of immature gamma-aminobutyric acid signaling on modulators of the gamma-aminobutyric acid type A receptor, such as the benzodiazepines, is not known in infants.

Methods
Nociceptive processing was measured using behavioral and electrophysiological recordings of hind limb flexor withdrawal threshold and magnitude to mechanical and thermal stimulation of the hind paw. The effects of midazolam (0.1-10 mg/kg subcutaneously, 0.1 mg/kg intrathecally) or saline treatment were compared in rats aged 3, 10, 21, and 40 days (adult). The sedative action of midazolam was assessed at each age using righting reflex latencies.

Results
Midazolam dose-dependently decreased mechanical reflex thresholds and increased mechanical and thermal reflex magnitudes in neonates. In older rat pups and adults, midazolam had the reverse effect, increasing thresholds and decreasing reflex magnitude. These differences were mediated supraspinally; intrathecal administration of midazolam did not affect flexion reflexes at any age. Midazolam had no sedative action in the youngest rats; sedation increased gradually through postnatal development.

Conclusions
The results show a striking reversal in the effects of midazolam on nociception and sedation in rats between postnatal days 3 and 10. Midazolam fails to sedate young rats and sensitizes their flexor reflex activity. The sedative and desensitizing effects of midazolam are not observed until later in life after maturation in supraspinal centers. The results indicate a need to better understand the pharmacology of drugs used routinely in neonatal intensive care.
Intrathecal Magnesium Sulfate Administration at the Time of Experimental Ischemia Improves Neurological Functioning by Reducing Acute and Delayed Loss of Motor Neurons in the Spinal Cord
Authors: Jellish Walter S. , Zhang Xin , Langen Kenneth E. , Spector Matthew S. , Scalfani Michael T. , White Fletcher A. 
Published: March 2009

Background
In this study, the authors determined the effect of magnesium sulfate on intrathecal glutamate concentrations, hindlimb motor function, and histopathology after a transient episode of spinal cord ischemia.

Methods
Fifty-two New Zealand White rabbits underwent spinal cord ischemia for 30 min. Fifteen minutes before ischemia, animals received intrathecal magnesium sulfate (MgSO4) (3 mg/kg) or placebo (artificial cerebrospinal fluid). Intrathecal microdialysis samples were measured for glutamate using high-performance liquid chromatography. Neurologic function and spinal cord histopathology were assessed throughout the recovery period.

Results
Intrathecal glutamate levels in placebo-treated animals were higher after spinal cord ischemia compared with sham- and MgSO4-treated animals. MgSO4-treated animals had increased lower extremity motor function compared with the placebo group (64.7% vs 14.3%, P < 0.01). Histologic examination of placebo-treated animals revealed significant motor neuron cell loss at thoracolumbar levels by Day 7 (P < 0.05), whereas lower lumbar regions displayed significant neuron loss on Day 1. Spinal cords from MgSO4-treated animals exhibited less neuronal loss in lumbar regions. Similar effects were present in the thoracolumbar segments on Day 7. A significant correlation existed between diminished neuronal loss and hind leg movement (Tarlov score) and demonstrates that the neurologic outcome after MgSO4 treatment was related to lower lumbar ventral horn cell survival (r2 = 0.812, P < 0.001).

Conclusions
These results demonstrate that MgSO4 affords significant spinal cord motor neuron protection by diminishing acute neuronal loss at the foci of the ischemic injury (L3-L6) with delayed neuronal degeneration in adjacent spinal cord regions (T7-L2).
Quantitative Architecture of the Brachial Plexus and Surrounding Compartments, and Their Possible Significance for Plexus Blocks
Authors: Moayeri Nizar , Bigeleisen Paul E. , Groen Gerbrand J. 
Published: March 2009

Background
Nerve injury after regional anesthesia of the brachial plexus (BP) is a relatively rare and feared complication that is partly attributed to intraneural injection. However, recent studies have shown that intraneural injection does not invariably cause neural injury, which may be related to the architecture within the epineurium. A quantitative study of the neural components and the compartment outside BP was made.

Methods
From four frozen shoulders, high-resolution images of sagittal cross-sections with an interval of 0.078 mm were obtained using a cryomicrotome to maintain a relatively undisturbed anatomy. From this data set, cross-sections perpendicular to the axis of the BP were reconstructed in the interscalene, supraclavicular, midinfraclavicular, and subcoracoid regions. Surface areas of both intraepineurial and connective tissue compartments outside the BP were delineated and measured.

Results
The nonneural tissue (stroma and connective tissue) inside and outside the BP increased from proximal to distal, being significant between interscalene/supraclavicular and midinfraclavicular/subcoracoid regions (P < 0.001 for tissue inside BP, P < 0.02 for tissue outside BP). The median amount of neural tissue remained approximately the same in the four measured regions (41.1 +/- 6.3 mm; range, 30-60 mm). The ratio of neural to nonneural tissue inside the epineurium increased from 1:1 in the interscalene/supraclavicular to 1:2 in the midinfraclavicular/subcoracoid regions.

Conclusion
Marked differences in neural architecture and size of surrounding adipose tissue compartments are demonstrated between proximal and distal parts of the brachial plexus. These differences may explain why some injections within the epineurium do not result in neural injury and affect onset times of BP blocks.
Propofol Restores Brain Microvascular Function Impaired by High Glucose via the Decrease in Oxidative Stress
Authors: Nakahata Katsutoshi , Kinoshita Hiroyuki , Azma Toshiharu , Matsuda Naoyuki , Hama-Tomioka Keiko , Haba Masanori , Hatano Yoshio 
Published: March 2009

Background
Vascular dysfunction induced by hyperglycemia has not been studied in cerebral parenchymal circulation. The current study was designed to examine whether high glucose impairs dilation of cerebral parenchymal arterioles via nitric oxide synthase, and whether propofol recovers this vasodilation by reducing superoxide levels in the brain.

Methods
Cerebral parenchymal arterioles in the rat brain slices were monitored using computer-assisted videomicroscopy. Vasodilation induced by acetylcholine (10 to 10 m) was obtained after the incubation of brain slices for 60 min with any addition of l-glucose (20 mm), d-glucose (20 mm), or propofol (3 x 10 or 10 m) in combination with d-glucose (20 mm). Superoxide production in the brain slice was determined by dihydroethidium (2 x 10 m) fluorescence.

Results
Addition of d-glucose, but not l-glucose, reduced arteriolar dilation by acetylcholine, whereas the dilation was abolished by the neuronal nitric oxide synthase inhibitor S-methyl-l-thiocitrulline (10 m). Both propofol and the superoxide dismutase mimetic Tempol (10 m) restored the arteriolar dilation in response to acetylcholine in the brain slice treated with d-glucose. Addition of d-glucose increased superoxide production in the brain slice, whereas propofol, Tempol, and the nicotinamide adenine dinucleotide phosphate (NAD[P]H) oxidase inhibitor apocynin (1 mm) similarly inhibited it.

Conclusions
Clinically relevant concentrations of propofol ameliorate neuronal nitric oxide synthase-dependent dilation impaired by high glucose in the cerebral parenchymal arterioles via the effect on superoxide levels. Propofol may be protective against cerebral microvascular malfunction resulting from oxidative stress by acute hyperglycemia.