bluuebunny/crossref_metadata_2025_split huggingface dataset:
Relations between suicidal ideation and dimensions of depressive symptoms in high‐school students
Authors: Chabrol Henri , Rodgers Rachel , Rousseau Amélie 
Published: September 2006

AbstractThe aim of the study was to evaluate the link between the different dimensions of depressive symptoms and suicidal ideation in adolescents. A sample of 1057 adolescents completed the CES‐D (Center for Epidemiological Studies Depression Scale) and three additional items measuring suicidal ideation. The four dimensions of depressive symptoms on the CES‐D (Depressed Affect, Loss of Positive Affect, Somatic and Retarded Activity, Interpersonal) were entered into regression analyses predicting the presence of any suicidal ideation and of the wish to kill oneself among participants with moderate/severe depressive symptoms (). For both boys and girls Depressed Affect was the main significant predictor of the presence of any suicidal ideation and of the wish to kill oneself. There were two additional significant predictors for boys: Loss of Positive Affect positively predicted the presence of any suicidal ideation; Somatic and Retarded Activity negatively predicted the presence of the wish to kill oneself.
Transsphenoidal Adenomectomy
Authors: McEwen Donna R. 
Published: September 2006

ABSTRACTThe pituitary gland is a complex organ controlling many of the body's hormonal and metabolic functions. The gland's complexity and location in the brain have a serious impact on the diagnosis and treatment of pituitary pathology. Several surgical approaches are available to treat pituitary tumors; however, the transsphenoidal approach allows the surgeon to remove the tumor with minimal damage to surrounding intracranial structures. Perioperative nurses should be knowledgeable about pituitary pathology (ie, mass effect, hormonal involvement), patient treatment options, surgical approaches, and possible postoperative complications to provide quality nursing care. AORN J 61 (Feb 1995) 321–337.
Folliculinum: Efficacy in premenstrual syndrome
Authors: Martinez Bruno 
Published: September 2006

SummaryThe severity of Premenstrual Syndrome (PMS) and the effect of Folliculinum 9 cH in 32 patients was analyzed using a questionnaire. Symptoms of PMS were troublesome in 84% of patients prescribed Folliculinum, 88% of patients showed a satisfactory response to treatment.
Homœopathy—A pilot study of the attitudes and awareness of pharmacy staff in the Stoke-on-Trent area
Authors: Davies Maurice , Kayne Steven 
Published: September 2006

AbstractThe survey was designed to study the attitudes of a sample of pharmacists, technicians and unqualified staff towards homœopathy, and their understanding of the principles involved.The most significant findings were that the majority of those who expressed a view (i.e. excluding the don't knows) were favourable to homœopathy, but there was little understanding of the subject. Most pharmacists thought that homœopathic medicines worked ‘by faith’. An urgent need for an education programme was demonstrated.
Homœopathy as a practical alternative to traditional obstetric methods
Authors: Ventoskovskiy B.M. , Popov A.V. 
Published: September 2006

AbstractA clinical trial was carried out to determine the efficacy of predelivery homœopathic and ‘traditional’ prophylaxis of uterine inertia and post partum haemorrhage. Under our observation, there were 206 pregnant women characterized by high risk of uterine contractile function disturbances. The 1st group of pregnant women (n=102) received only homœopathy. The 2nd group (n=104) received conventional medical preparations including oestrogenic hormones. We studied a use of homœopathic drug complex possessing ‘relatively narrow range of influence’.Clinical examination, foetal cardiomonitoring and ultrasound scanning were carried out in each case. The normal methods were used to treat uterine inertia, foetal distress and post partum haemorrhage.In our opinion homœopathy can be an effective method for prophylaxis of disturbances of uterine contractile function in delivery and at the postnatal stage for pregnant women at high risk of complications.
Effect of Viscum album preparations on gastric chief cells and DNA methylation by N-methyl-N′-nitro-N-nitrosoguanidine
Authors: Defize J. , Zwiers T. , Pals G. , Kipp J.B.A. , Eriksson A.W. 
Published: September 2006

AbstractThe protective effect of extracts of mistletoe Viscum album (Iscador) with reference to carcinogenesis was tested on in vitro cultured porcine gastric chief cells. Putative protection against in vitro methylation of lambda DNA by N-methyl-N′-nitro-N-nitrosoguanidine (MNNG) was studied with restriction endonucleases. Preparations of Iscador from mistletoe grown on oak as host tree had a high cytotoxic effect on gastric chief cells, with an LC50 after 24 hrs that ranged between 0.01 and 0.03 mg/ml. At 0.01 mg/ml, Iscador was also found to protect lambda DNA from methylation or destruction by MNNG. During the course of this study a high variability was found both in cytotoxicity and protection rate against methylation which we attribute to batch to batch differences. Thus the LC50 for Iscador MH 86 L12 was 0.005 mg/ml, while for MH87 D24 it was 0.05 mg/ml after 24 hrs. The Iscador batch W frf 50 mg/ml, which was made from a fresh plant extract at the Hiscia Institute, showed less variability. Results are therefore given for this batch of Iscador only.
Effects of homœopathic preparations of organic acids and minerals on the oxidative metabolism of human neutrophils
Authors: Chirumbolo Salvatore , Signorini Andrea , Bianchi Ivo , Lippi Guiseppe , Bellavite Paolo 
Published: September 2006

AbstractA number of different potencies of commercially available homœopathic preparations in saline solution were tested for their ability to regulate the oxidative metabolism (superoxide production) and adhesion function of human neutrophils in vitro. 15% to 30% inhibition of oxidative metabolism was caused by Sulphur 6x, Manganum phosphoricum 6x and 8x, and Magnesium phosphoricum 6x and 8x. Phosphorus slightly reduced superoxide production, with varying results in a series of experiments. Using Magnesium phosphoricum and Phosphorus, small inhibitory effects (8–11%) were noted event at high potencies. Among the organic acids, a group (Acidum malicum 4x and Acidum fumaricum 4x) enhanced superoxide production, while others either inhibited the response (Acidum citricum and Acidum succinicum, 3x and 4x) or had no effect (Acidum α-ketoglutaricum and Acidum cis-aconitum). Attempts to reproduce these effects using solutions prepared in the laboratory confirmed the inhibitory effects of Manganum phosphoricum 6x and of organic acids in the 3x, while other data indicated that critical factors in the methodology of preparation may affect the results.
Calcarea carbonica
Authors: Shore Jonathan 
Published: September 2006

SummaryThe things you need to know by heart, the good confirmations, are: chilly people, worse for cold, worse for cold damp, worse for exertion, worse for ascending, worse at the full moon. Frequent colds, sleeps on left side, strong desire for sweets, eggs, salt, cheese, icecream. Fear of heights, insanity, cancer, mice, infections. Despair of recovery. Vertigo especially turning quickly or from heights. Low back pain. Lumbago. Nails break easily. Feet icy cold and then warm up later. Leg cramps especially at night during sleep.These are symptoms which you must know, not just individually but as a pattern. We are pattern recognizers and if you know these symptoms as a coherent whole when you take your case you have all this information. You spend 1 fi hours with a patient and collect this volume of information and then do not know where to begin. But look at your case and see first one symptom, then another—overweight, chilly, worse damp weather, desires sweets and salt—and you can forget anything else and give Calcarea, for this is a Calcarea case. You have these things together as a pattern. It is actually a fairly simple medicine and you will mostly miss it because it is a very big one. The patients will give you many symptoms and you will get lost in them, missing the simple pattern that makes Calcarea. Most of the Calcareas I miss, which are then pointed out to me by my colleagues, are of that nature.
Critical evaluation of papers reviewing controlled clinical trials in homoeopathy
Authors: Melchart D. , Brandmaier R. , Eitel F. , Linde K. 
Published: September 2006

AbstractAn analysis was made of papers reviewing controlled clinical trials designed to assess efficacy of homoeopathic treatment strategies, the aim being to demonstrate selective and critical assessment of such papers. The papers were systematically collected and evaluated for content and quality using predefined criteria, finally comparing the results. 9 of 41 papers considered in detail after screening the literature met the criteria for inclusion in the analysis. Each considered between 22 and 107 trials. 7 papers met 2 or less of the predefined quality criteria, one met 6 and one 8 criteria. Only 1 of the papers allowed full representation and reproducible evaluation of treatment strategies for the controlled clinical studies considered in that paper. The analysis has shown that review papers must clearly specify issues, objectives, methods of literature screening and quality assessment.
Evaluation of homœopathic therapy in 129 asymptomatic HIV carriers
Authors: Singh V.P. , Singh V. , Dey S.K. , Rastogi D.P. 
Published: September 2006

AbstractTo assess the role of homœopathic medicines in the treatment of the asymptomatic phase of HIV infection, a pilot research study was undertaken by the Central Council for Research in Homœopathy (India) starting in May 1989. 129 symptomatic HIV carriers (120 male and 9 female) were treated with homœopathic medicines on the basis of the individuals' constitutional (both mental/emotional and physical) characteristics. The medicines were prescribed in potencies varying from 30 CH to 10M and in varying dosage, depending on the age and constitution of the individual patients. 12 of the patients studied have reverted back to negative serology for HIV antibodies after treatment varying from 3 to 16 months (mean duration of treatment between entry and reversal of seroconversion for HIV antibodies 7.25 months). All patients who continue to remain symptom free are receiving follow-up treatment. Efforts are being made to evaluate their haematological and immunological status in detail.
Cost-effectiveness of homœopathic treatment in a dental practice
Authors: Feldhaus H.-W. 
Published: September 2006

AbstractDentists who accept social security patients in Germany today are bound by a large number of rules and regulations which impose severe limits on their free choice of treatment, cost-effectiveness being a prime consideration.The treatment of acute conditions predominates in a modern compulsory insurance practice. The author analysed his own case records and the statistics provided by the KZV (association of dental practitioners for patients with compulsory insurance) for the period from 1983 to 1990 to establish the effect of introducing consistent use of homœopathic treatment from the end of 1984 on the frequency with which certain standard treatments were required. The results were compared with the average figures of other dentists and a computation made of potential economic advantages at a national level.
Homœopathy and disability
Authors: Vickers Andrew 
Published: September 2006

AbstractThe classification of disability is outlined. The limitations of the medical model when applied to disability and the practical problems of disabled people are discussed. The literature on homœopathic treatment of disability is reviewed. The basic causes of disability are often irreversible, but homœopathy may have an important role to play in the relief of secondary symptoms. Homœopathic treatment of people with disabilities, especially children, requires further study.
Tetanus neonatorum
Authors: Pai P.N. 
Published: September 2006

SummaryA detailed study of 164 cases of tetanus neonatorum is presented.Cases were divided into 4 groups and were given different types of treatment. The results of the different therapies are analysed and compared.
Stramonium, hitherto not thought of as a possible remedy for tetanus, was found to be effective in this disease along with Nux vomica. The brief indications for these remedies are given.Overall mortality in the present series is also compared with the mortality rates in different countries.
Copper sulphate and plant growth
Authors: Netien G. , Boiron J. , Marin A. 
Published: September 2006

SummaryThe experiments seem to have shown that a 15 cH copper sulphate dilution does favourably affect the germination and growth of seeds from plants previously treated with that substance.On the other hand, copper sulphate-treated seeds grown on this 15 cH dilution excrete copper much more rapidly than treated seeds grown on potentized double distilled water. This means that the dilution produces a real detoxication of the seed which in its development then clearly resembles a normal, unpoisoned seed.
Low back pain
Authors: Hoa Jacques Hui Bon 
Published: September 2006

Summary
Nux vomica turning in bed agg., motion amel. Sulphur standing agg. rising from sitting agg. rising from stooping agg. pain in sacral region extending to groin Rhus tox. prescribed on its modalities only Carcarea fluor. when Rhus tox. fails Calcarea carb. special type local sweats, especially head sweat coldness of local part (vertex); subjectively respiration difficult on least exertion Sepia pressure amel. varices leucorrhoea Sepia symptom complex Colocynthis stitching pain in lumbar region intermittent pain pain confined to a small spot (Kali bich.) contracture Cobaltum pain in lumbosacral region, sitting agg. Berberis pain extending around abdomen Hypericum after spinal injury Kali carb. lumbago after parturition Phosphorus in a typical Phosphorus patient. Difficult cases Antimonium tart. in very acute cases. The slightest effort to move causes retching and cold clammy sweat. Bryonia pain agg. slightest motion Variolinum in very acute cases
Plant responses to homœopathic remedies
Authors: Jones Raynor L. , Jenkins Michael D. 
Published: September 2006

SummaryOver the past 50 years several experiments to demonstrate the biological effects of homœopathic potencies have been devised. All of them have had short-comings: mainly in terms of reproducibility of the method itself and the analysis of the results. This paper describes a simple biological model using the growth responses of wheat coleoptiles to various homœopathic potencies. The results described show that the method is reproducible and that biological activity can be detected at extremely high dilutions. Succussion appears to be an essential part of the preparation of a homœopathic potency. A theoretical basis for this observation is discussed.
The amazing Tree of Heaven
Authors: Munro C.K. 
Published: September 2006

SummaryAlthough, to date, only six cases were recorded it was considered importantenough to mention them because of the dramatic response in 100% of patients.Three main symptoms were present in all cases, but the only criterion for inclusionin the trial was a positive Paul Bunnell test (thus confirming the diagnosis).Most homœopaths, including myself, would most likely have used 6x potencyor even 30th, but might not have considered a higher one in such a case. It was fortuitous that I used the 10M. It does confirm the usefulness of very high potencies. I suspect that the lower potency would have worked, I hazard a guess probably not as well and not so permanently.I would be more than keen for other homœopaths to gather such cases undersimilar conditions (all must have the positive test) and I shall be happy to receive such attested cases.If we can gather, say, 50 cases, then I shall write a paper for the medicaljournals…then, let us see the reaction! Meantime, I suggest, we have a cure for this very unpleasant condition.
Provings—Planning and protocol
Authors: Nagpaul V.M. 
Published: September 2006

AbstractProvings provide knowledge about the instruments that we, as homœopaths, use in combating human sickness.A vast amount of pre-planning and laying of protocols is necessary in conducting the provings for the purposes of achieving scientific validity of the work. The author has therefore dwelt only upon various stages of planning and protocols necessary in conducting successful provings.
Controlled double-blind trial with Baryta carbonica 15 CH versus placebo in a group of hypertensive subjects confined to bed in two old people's homes
Authors: Bignamini M. , Bertoli A. , Consolandi A.M. , Dovera N. , Saruggia M. , Taino S. , Tubertini A. 
Published: September 2006

AbstractTaking into account the toxicology of soluble barium salts, the authors treated 32 hypertensive subjects who were confirned to bed in two old people's homes with Baryta carbonica 15 CH versus placebo in a randomized double-blind study. Seventeen patients were given Baryta carbonica and 15 placebo. Taking the groups as a whole, no statistically significant differences were found between the effects of placebo and active drug on the blood pressure. But the four subjects who had been prospectively considered sensitive and were treated with Baryta carbonica gave strongly positive results. Some interesting conclusions were arrived at both from the general medical and the homœopathic point of view.
A case of tuberous sclerosis treated with Artemisia vulgaris
Authors: Jack R.A.F. 
Published: September 2006

AbstractA two-year-old boy suffering from tuberous sclerosis is described. His salaam spasms had not been controlled by a combination of sodium valporate and nitrazepam, but decreased and finally ceased after medication with Artemisia 30, despite nitrazepam having been discontinued during this treatment.
Cholera 1854: update
Authors: Leary Bernard 
Published: September 2006

AbstractIn October 1987 a paper was published in this journal1 attempting to assess the claims made by the British Homœopathic Society concerning the efficacy of the treatment of cholera at Golden Square during the 1854 epidemic. Details of the treatment were not available at that time and had to be deduced. This paper fills in those details. The view expressed then that homœopathy played a major part in bringing about substantially better results than the allopaths is reinforced. For background information the reader is referred to the original paper.
Stochastic resonance and the homoeopathic effect
Authors: Ruiz Ma Guadalupe , Torres José-Leonel 
Published: September 2006

AbstractPotentization of homoeopathic medicines by successive dilutions and succussion at each step is interpreted in terms of stochastic resonance, a non-linear response of certain systems when perturbed by noise and a weak periodic signal, which increasingly enhanced at the output as the magnitude of the noise grows towards an optimal value for maximum signal amplification. The possible relevance of stochastic resonance in other physiological phenomena like the kindling effect, where epileptic convulsions are induced in rats and other animals by periodic stimulation of the brain with weak electric signals, is also considered.
Homoeopathy and the US primary care physician
Authors: Berman Brian M. , Hartnoll Susan M. , Singh Betsy B. , Singh B. Krishna 
Published: September 2006

AbstractThe purpose of this study was to assess US primary care physicians' levels of knowledge of and attitudes towards homoeopathy, as well as their practice and referral patterns, and desire for training in this field. Previous studies indicate low practice and referral rates, but high interest in training has been suggested by an earlier regional study. A structured, self-administered questionnaire was mailed to a hierarchical, stratified, random sample of physicians drawn from the American Medical Association membership of primary care specialists. Results of this study show a high degree of interest in training (49%) in homoeopathy despite current low practice (5.9%) and referral rates (13.8%). In addition, a total of one third of the physicians said they either would use or have used homoeopathy in their own practices. A shortfall exists between the knowledge and desire for knowledge about homoeopathy among primary care physicians and the availability or amount of information and training accessible in the United States.
Targeted projection pursuit for visualizing gene expression data classifications
Authors: Faith Joe , Mintram Robert , Angelova Maia 
Published: September 2006

Abstract
We present a novel method for finding low-dimensional views of high-dimensional data: Targeted Projection Pursuit. The method proceeds by finding projections of the data that best approximate a target view. Two versions of the method are introduced; one version based on Procrustes analysis and one based on an artificial neural network. These versions are capable of finding orthogonal or non-orthogonal projections, respectively. The method is quantitatively and qualitatively compared with other dimension reduction techniques. It is shown to find 2D views that display the classification of cancers from gene expression data with a visual separation equal to, or better than, existing dimension reduction techniques.
Availability: source code, additional diagrams, and original data are available from
Contact: joe.faith@unn.ac.uk
Supplementary information: Supplementary data are available at Bioinformatics online.
Discovering disease-genes by topological features in human protein–protein interaction network
Authors: Xu Jianzhen , Li Yongjin 
Published: September 2006

Abstract
Motivation: Mining the hereditary disease-genes from human genome is one of the most important tasks in bioinformatics research. A variety of sequence features and functional similarities between known human hereditary disease-genes and those not known to be involved in disease have been systematically examined and efficient classifiers have been constructed based on the identified common patterns. The availability of human genome-wide protein–protein interactions (PPIs) provides us with new opportunity for discovering hereditary disease-genes by topological features in PPIs network.
Results: This analysis reveals that the hereditary disease-genes ascertained from OMIM in the literature-curated (LC) PPIs network are characterized by a larger degree, tendency to interact with other disease-genes, more common neighbors and quick communication to each other whereas those properties could not be detected from the network identified from high-throughput yeast two-hybrid mapping approach (EXP) and predicted interactions (PDT) PPIs network. KNN classifier based on those features was created and on average gained overall prediction accuracy of 0.76 in cross-validation test. Then the classifier was applied to 5262 genes on human genome and predicted 178 novel disease-genes. Some of the predictions have been validated by biological experiments.
Contact: jianzxu@hotmail.com
Supplementary information: Supplementary data are available at Bioinformatics online.
Synchronization of Mammalian Cell Cultures in Mitosis Using Selective Detachment
Authors: Galgano Paul J. , Schildkraut Carl L. 
Published: September 2006

INTRODUCTIONThis protocol describes a method for synchronizing monolayer cells in mitosis using selective detachment from their substrate. During mitosis, cells become more spherical, causing them to become more loosely attached to their substrate. The “rounded up” cells are selectively detached by tapping the culture flask, resulting in a population in which as many as 90-98% of the cells are in mitosis. The drug nocodazole is used to increase the percentage of cells undergoing mitosis before detachment is performed. This procedure has been applied to mouse fibroblast and CHO (Chinese hamster ovary) cells. Since different cell types may attach differently, it will be necessary to determine the amount of force needed to remove loosely attached cells and the mitotic cells.