bluuebunny/crossref_metadata_2025_split huggingface dataset:
Do plus-size models really benefit obese consumers? Investigating the influence of plus-size models on negative emotions and mental imagery
Authors: Yim Mark Yi-Cheon , Kim Eunice (Eun-Sil) , Ahn Hongmin 
Published: March 2024

PurposeIn keeping with recent body image social trends, consumer demand for the adoption of plus-size models is increasing, although the use of thin models remains prevalent. The current study explores how consumers process information about fashion products displayed on different sizes of models in advertisements, focusing on model and consumer body sizes and both genders. As an underlying mechanism explaining how the relationship between model and consumer body sizes shapes consumer purchase intention, this study explores the role of guilt, shame and mental imagery.Design/methodology/approachThe current study uses a text analytics technique to identify female consumers' general opinions of thin models in advertising. Employing a 3 (consumer body size: normal, overweight, obese) × 2 (model body size: thin, plus-size) × 2 (gender: male, female) between-subjects online experiment (n = 718), the main study comparatively analyzes the influences of plus-size and thin models on consumer responses.FindingsThe results reveal that, despite body positivity movements, thin models still generate negative emotions among female consumers. For obese female consumers, advertisements featuring plus-size models produce fewer negative emotions but not more mental imagery than advertisements featuring thin models. Conversely, for obese male consumers, advertisements featuring plus-size models generate more mental imagery but not more negative emotions than advertisements featuring thin models. The results also reveal that the relationship between consumer body size and guilt is moderated by perceived model size, which is also moderated by gender in generating mental imagery. While guilt plays a mediating role in enhancing mental imagery, resulting in purchase intention, shame does not take on this role.Originality/valueThis study is the first to present an integrated model that elucidates how consumers with varying body sizes respond to different sizes of models in advertising and how these responses impact purchase intentions.Research limitations/implicationsOur findings only apply to contexts where consumers purchase fashion clothing in response to advertisements featuring thin versus plus-size models.Practical implicationsExposing normal-size consumers to plus-size models generates less mental imagery, and thus, practitioners should seek to match the body sizes of the models featured in advertising to the body sizes of their target audience or ad campaigns that include both plus-size and thin models may help improve message persuasiveness in fashion advertising. Moreover, guilt-appeal advertising campaigns using thin models would appeal more to thin consumers of both genders than shame-appeal advertising.
A consensus map for Ladakh’s development as potential geotourism destination: key drivers
Authors: Khalid Rimsha , Kumar Rajinder , Sinha Rupa , Selem Kareem M.M. , Raza Mohsin 
Published: March 2024

Purpose
Given the prevalence of protecting geoheritage tourism sites, Ladakh has enormous potential. However, Ladakh’s potential and developments in its growth as a geotourism destination have received scant consideration. As such, this paper aims to explore Ladakh’s key drivers as a potential geotourism destination through cognitive dissonance and protection motivation theories.

Design/methodology/approach
This paper conducted in-depth interviews with 86 geoscientists and tourism professionals to assess Ladakh’s potential as a geotourism destination. This paper used a qualitative approach to congregate four constructs based on the image difference of the consensus map.

Findings
Because of the interviewees’ heterogeneity and uniqueness, meaningful constructs in the consensus were included for each figure and cloud words. This paper concluded that four drivers are the main forces behind geotourism development.

Originality/value
This paper explores the drivers – geotourism services, legislative requirements, experiential geotourism and SPARC (scientific, preservation, aesthetic, recreational, cultural) values – affecting geotourism in Ladakh. It is feasible to lessen the negative effects of overtourism and make sure that Ladakh’s distinctive nature is preserved for future generations by implementing sustainable tourism practices.
Precious metal prices: a tale of four US recessions
Authors: Agnese Pablo , Garcia del Barrio Pedro , Gil-Alana Luis Alberiko , Perez de Gracia Fernando 
Published: March 2024

Purpose
The purpose of this paper is to examine the degree of persistence in four precious metal prices (i.e. gold, palladium, platinum and silver) during the last four US recessions.

Design/methodology/approach
Using daily price data for gold, palladium, platinum and silver running from July 2, 1990, to March 21, 2022, and dating of business cycles in the USA provided by NBER (2022), the paper uses fractional integration to test the degree of persistence of precious metal prices.

Findings
The empirical analysis shows the unrelenting prominence of gold in relation to other precious metals (palladium, platinum and silver) as a hedge against market uncertainty in the post-pandemic new era.

Originality/value
Two are the main contributions of the paper. Firstly, the authors contribute to the commodity markets and finance literature on precious metal price modelling. Secondly, the authors also contribute to the literature on commodity markets and business cycles with a special focus on recessionary periods.
Enterprise digital transformation and audit quality: Empirical evidence from annual reports of Chinese listed companies
Authors: Fang Fang , Mo Dongyan , Chen Ruyi 
Published: March 2024

AbstractThis study explores how enterprise digital transformation affects audit quality. The results show that the relationship between enterprise digital transition and audit quality takes on a U‐shaped. Mechanism test results indicate that during the initial stages of digitization, the restrictive effect of auditor's professional competence mismatch predominates. Conversely, during the mature stages of digitization, the promotion effect of improved auditor's substantive independence predominates. Heterogeneity tests demonstrate that this U‐shaped relationship is significant primarily within the sample set of short audit tenure and state‐owned enterprises. The study reveals the internal mechanism of the impact of enterprise digital transition on audit quality, offering empirical evidence to comprehend the incremental dynamic effects of enterprise digitalization and mitigate potential adverse consequences throughout the transformation process.
Prison geographies: Nine disciplinary approaches
Authors: Bloch Stefano , Olivares‐Pelayo Enrique Alan 
Published: March 2024

AbstractMotivated by a critical concern for state‐sanctioned coercion, control, and containment across “free society,” geographers have extended Foucault's concept of “the carceral” to more and increasingly diffuse spaces and processes. In this paper, however, we aim to re‐center the prison in the carceral geographies literature, reasserting it as the sine qua non of the subfield. In doing so, we organize geographers' analysis of prisons into nine conceptual categories based on this journal's areas of geographical exploration: cultural, development, economic, environment, geographic information systems & quantitative, historical, political, social, and urban. In addition to providing a review of existing prison research in geography, we illustrate the diversity of disciplinary approaches to that most “complete and austere” of institutions.
ASSET‐MARKET SENTIMENTS AND BUSINESS CYCLE FLUCTUATIONS
Authors: Liu Xuewen , Wang Pengfei , Xu Sichuang 
Published: March 2024

AbstractWe present a tractable model that accommodates asset‐market sentiment in a standard Dynamic Stochastic General Equilibrium (DSGE) setting, allowing us to quantitatively evaluate sentiment‐driven macroeconomic fluctuations. In our model, changes in households' perceived uncertainty about housing prices lead to self‐fulfilling fluctuations in housing prices, which then impact investment and output through entrepreneurs' collateral constraints. Household sentiment shocks hence are transmitted and propagated to the macroeconomy, generating boom–bust cycles. Uncertainty, housing prices, and the real economy are linked. Quantitatively, the sentiment shock in the form of risk–panic is a crucial driver of business cycle fluctuations despite the presence of various competing shocks.
Steroid receptor coactivator 1 promotes human hepatocellular carcinoma invasiveness through enhancing MMP‐9
Authors: Tong Zhangwei , Zhang Yong , Guo Peng , Wang Wei , Chen Qiang , Jin Jing , Liu Shixiao , Yu Chundong , Mo Pingli , Zhang Lei , Huang Junli 
Published: March 2024

AbstractSRC‐1 functions as a transcriptional coactivator for steroid receptors and various transcriptional factors. Notably, SRC‐1 has been implicated in oncogenic roles in multiple cancers, including breast cancer and prostate cancer. Previous investigations from our laboratory have established the high expression of SRC‐1 in human HCC specimens, where it accelerates HCC progression by enhancing Wnt/beta‐catenin signalling. In this study, we uncover a previously unknown role of SRC‐1 in HCC metastasis. Our findings reveal that SRC‐1 promotes HCC metastasis through the augmentation of MMP‐9 expression. The knockdown of SRC‐1 effectively mitigated HCC cell metastasis both in vitro and in vivo by suppressing MMP‐9 expression. Furthermore, we observed a positive correlation between SRC‐1 mRNA levels and MMP‐9 mRNA levels in limited and larger cohorts of HCC specimens from GEO database. Mechanistically, SRC‐1 operates as a coactivator for NF‐κB and AP‐1, enhancing MMP‐9 promoter activity in HCC cells. Higher levels of SRC‐1 and MMP‐9 expression are associated with worse overall survival in HCC patients. Treatment with Bufalin, known to inhibit SRC‐1 expression, significantly decreased MMP‐9 expression and inhibited HCC metastasis in both in vitro and in vivo settings. Our results demonstrated the pivotal role of SRC‐1 as a critical modulator in HCC metastasis, presenting a potential therapeutic target for HCC intervention.
Association between sex hormones and bone age in boys aged 9–18 years from China
Authors: Shu Wen , Niu Wenquan , Zhang Yaqin , Li Hui 
Published: March 2024

AbstractThis study aimed to analyse the association between sex hormones and bone age (BA) in boys aged 9–18 years, both individually and interactively, and further to explore whether nutritional status may influence this association. A retrospective analysis was performed among 1382 Chinese boys with physical measurements, sexual characteristics, BA radiographs and sex hormone indicators from February 2015 to February 2022. A total of 470 (34.0%) boys had advanced BA. BA was positively associated with estradiol, luteinizing hormone (LH), follicle‐stimulating hormone (FSH) and testosterone in both advanced and normal BA groups after adjusting for age, genetic height and body mass index. Multiple logistic regression showed that after adjusting for covariates, estradiol (odds ratio [OR] = 1.66, 95% confidence interval [CI]: 1.14–2.12), LH (OR = 1.43, 95% CI: 1.04–1.96), and testosterone (OR = 1.58, 95% CI: 1.17–2.13) were significantly associated with the increased risk of advanced BA in boys, and the association was reinforced when these hormones were interactively explored. Stratified by nutritional status, the interaction between estradiol, LH, and testosterone showed a strong association with advanced BA in boys with normal weight.
Mendelian randomization analysis reveals a causal effect of Streptococcus salivarius on diabetic retinopathy through regulating host fasting glucose
Authors: Li Jingjing , Zheng Gongwei , Jiang Dingping , Deng Chunyu , Zhang Yaru , Ma Yunlong , Su Jianzhong 
Published: March 2024

AbstractDiabetic retinopathy (DR) is one of leading causes of vision loss in adults with increasing prevalence worldwide. Increasing evidence has emphasized the importance of gut microbiome in the aetiology and development of DR. However, the causal relationship between gut microbes and DR remains largely unknown. To investigate the causal associations of DR with gut microbes and DR risk factors, we employed two‐sample Mendelian Randomization (MR) analyses to estimate the causal effects of 207 gut microbes on DR outcomes. Inputs for MR included Genome‐wide Association Study (GWAS) summary statistics of 207 taxa of gut microbes (the Dutch Microbiome Project) and 21 risk factors for DR. The GWAS summary statistics data of DR was from the FinnGen Research Project. Data analysis was performed in May 2023. We identified eight bacterial taxa that exhibited significant causal associations with DR (FDR < 0.05). Among them, genus Collinsella and species Collinsella aerofaciens were associated with increased risk of DR, while the species Bacteroides faecis, Burkholderiales bacterium_1_1_47, Ruminococcus torques, Streptococcus salivarius, genus Burkholderiales_noname and family Burkholderiales_noname showed protective effects against DR. Notably, we found that the causal effect of species Streptococcus salivarius on DR was mediated through the level of host fasting glucose, a well‐established risk factor for DR. Our results reveal that specific gut microbes may be causally linked to DR via mediating host metabolic risk factors, highlighting potential novel therapeutic or preventive targets for DR.
4‐octyl itaconate alleviates cisplatin‐induced ferroptosis possibly via activating the NRF2/HO‐1 signalling pathway
Authors: Zhang Li , Song Wenao , Li Hua , Cui Xiaolin , Ma Jingyu , Wang Rongrong , Xu Yue , Li Ming , Bai Xiaohui , Wang Dawei , Sun Haihui , Lu Zhiming 
Published: March 2024

AbstractFerroptosis, characterized by iron‐dependent lipid reactive oxygen species (ROS) accumulation, plays a pivotal role in cisplatin‐induced ototoxicity. Existing research has suggested that in cisplatin‐mediated damage to auditory cells and hearing loss, ferroptosis is partially implicated. 4‐Octyl itaconate (4‐OI), derived from itaconic acid, effectively permeates cell membranes, showcasing potent anti‐inflammatory as well as antioxidant effects in several disease models. Our study aimed to investigate the effect of 4‐OI on cisplatin‐induced ferroptosis and the underlying molecular mechanisms. The survival rates of HEI‐OC1 cells and mice cochlea hair cells were measured by CCK8 and immunofluorescence, respectively. The auditory brainstem response (ABR) audiometry was used to detect changes in hearing thresholds in mice before and after treatment. Levels of ROS were evaluated by DCFH‐DA. Real‐time PCR quantified inflammatory cytokines TNF‐α, IL‐6 and IL‐1β. Network Pharmacology and RNA sequencing (RNA‐seq) analysis of the potential mechanism of 4‐OI resistance to cisplatin‐induced ferroptosis. The expressions of ferroptosis‐related factors (GPX4, SLC7A11 and PTGS2) and important antioxidant factors (NRF2, HO‐1, GCLC and NQO1) were tested by real‐time PCR, Western blot and immunofluorescence. Results demonstrated cisplatin‐induced significant ROS and inflammatory factor release, reduced NRF2 expression, hindered nuclear translocation and activated ferroptosis. Pretreatment with 4‐OI exhibited anti‐inflammatory and antioxidant effects, along with resistance to ferroptosis, ultimately mitigating cisplatin‐induced cell loss. In the present study, we show that 4‐OI inhibits cisplatin‐induced ferroptosis possibly through activation of the NRF2/HO‐1 signalling pathway, thereby exerting a protective effect against cisplatin‐induced damage to auditory cells, and providing a new therapeutic strategy for cisplatin‐induced hearing loss.
Unveiling the role of YARS1 in bladder cancer: A prognostic biomarker and therapeutic target
Authors: Wang YaXuan , Wang Jinfeng , Zhang Lu , He JiaXing , Ji Bo , Wang JianShe , Ding BeiChen , Ren MingHua 
Published: March 2024

AbstractYARS is responsible for catalysing the binding of tyrosine to its cognate tRNA and plays a crucial role in basic biosynthesis. However, its biological functions in bladder cancer remains to be proven. We analysed variations in YARS1 expression and survival in bladder cancer using multiple data sets, including TCGA‐BLCA, GSE13507 and bladder cancer‐specific tissue microarrays. Furthermore, we explored the biological functions of YARS1 using transcriptome data. Our findings revealed a noteworthy correlation between YARS1 and immune infiltration in bladder cancer, as determined using the XCELL algorithm and single‐cell analysis. In addition, we employed the TIDE algorithm to evaluate the responsiveness of different cohorts to immune checkpoint therapy. We investigated the regulatory associations between YARS1 and various aspects of bladder cancer, including senescence, ferroptosis and stemness. Finally, we established a ceRNA network that is directly linked to the overall prognosis, YARS1 can serve as a prognostic biomarker for bladder cancer; its interaction with MYC has implications for bladder cancer cell senescence, ferroptosis and stemness. Moreover, the identified ceRNA network has potential as a therapeutic target in bladder cancer.
Impacts of integration of mola with prawn–carp gher farming: An approach to enhance household fish consumption and family income
Authors: Islam Shikder Saiful , Mondal Saikat Ranjan , Bir Joyanta , Sabbir Wasim , Azad Md. Abul Kalam , Wahab Md. Abdul , Borski Russell , Huq Khandaker Anisul 
Published: March 2024

AbstractThis study investigated the production performance, household fish consumption, and commercial feasibility of prawn–carp–mola mixed gher farming system. Three treatments with different species compositions were compared: prawn + rohu, prawn + mola, and prawn + rohu + mola, each having different stocking densities. The results indicated that the integration of mola improved the utilization of feed protein by prawns. However, mola inclusion did not significantly affect the growth of prawn and rohu or the production system's cost. Mola inclusion led to a significant increase in the gross production, household consumption, and sale of mola, prawn, and rohu. It also increased gross returns, income above variable cost, and net returns to land, family labor, and management. In addition, the inclusion of mola significantly increased household consumption by increasing the intake of nutrient‐rich mola and overall fish consumption. This improvement in food consumption contributed to ensuring the nutritional requirements and food security of impoverished rural farmers, especially women and children. Consequently, the integration of small fish mola in prawn–carp gher farming systems is recommended as a beneficial practice for wider adoption, effectively addressing household nutrition security at the rural level and improving the livelihoods of farmers.
Microbial dominated Ca‐carbonates in a giant Pliocene cold‐seep system (Crotone Basin – South Italy)
Authors: Perri Edoardo , Borrelli Mario , Heimhofer Ulrich , Umbro Bruno , Santagati Pierluigi , Le Pera Emilia 
Published: March 2024

AbstractThe Pliocene cold‐seep carbonate of the Crotone Basin (South Italy) represents a key site for dimension, outcropping exposure and quality. These deposits form a large carbonate (calcite) body (350 m long, 100 m wide and 40 m thick), and are characterized by a conduit facies made of authigenic calcite interpreted as previously active gas/fluid escape pipes and by a pavement facies, depicted as the surrounding early calcite‐cemented bioclastic and siliciclastic sediments. Pavement facies are commonly colonized by chemosymbiotic and non‐chemosymbiotic macrofauna (Lucinid and Solemyid bivalves, gastropods and serpulids). The conduit microfacies is characterized by the inward accretion of dark micritic laminae alternating with whitish sparitic layers. The micritic laminae show a microbial peloidal to dendrolitic fabric, which commonly incorporates planktonic foraminifera and coprolites, whereas the crystalline layers consist of microsparitic and sparitic crusts of prismatic zoned calcite crystals. The pavement facies shows more variability, because it is typified by laminated microbial boundstones, chemosymbiotic–bivalves packstone, foraminiferal packstone/wackestone and hybrid arenites. The stratigraphic constraint coupled with the foraminiferal assemblage (planktonic taxa) suggest a deep‐water setting occasionally affected by siliciclastic sedimentary flows. The pavement facies also shows common brecciation features, suggesting the establishment of post‐depositional overpressure conditions due to the early cementation of the conduits, which triggered localized rock failure. Stable isotope analysis of the different facies reveals overall negative δ13C values (−6.8 to −37.4‰ Vienna PeeDee Belemnite), indicating the presence of a complex mixture of methane with other hydrocarbons consumed microbially via anaerobic oxidation of methane; whereas δ18O is relatively positive (0.0 to 3.4‰ Vienna PeeDee Belemnite) suggesting the possible dehydration of clay minerals and/or destabilization of gas hydrates. This study, besides helping in the definition of the migration pathways and modality of accumulation of hydrocarbon‐rich fluids, can also help in building more and more realistic models for the complex genesis of cold‐seep carbonates.
Investigating the accuracy and comparability of various lime prediction methods for Irish grassland mineral soils
Authors: Mackessy F. , McCarthy E. , Broderick E. , O'Donnell B. , Quille P. 
Published: March 2024

AbstractSoil pH is a foundational element of agronomy, profoundly influencing biological, chemical and physical soil processes. Adjusting soil pH is a paramount factor for enhancing soil health and productivity with far‐reaching environmental benefits. Over time soil naturally tends towards acidity, a process expedited by intensive agriculture practices. To determine the extent of necessary pH corrections, precise soil pH testing is imperative. Various methods including buffer systems, titrations, lime incubations and algorithms considering soil texture are used to assess a soil's lime requirement and each method carries distinct advantages and disadvantages. The Shoemaker–McLean–Pratt (SMP) buffer method is extensively used in Ireland and internationally; however, safety concerns owing to the use of hazardous chemicals required within the method have been highlighted. This study investigates various soil lime requirement tests and compares their performance against a lime incubation study. A proposed alternative to the SMP buffer test for Irish grassland soils is also investigated. Analysis of results obtained indicates that the SMP buffer method demonstrated the highest r2 value of .497 when correlated with lime incubation results, while the calcium hydroxide titration method closely aligns with the SMP buffer method with an r2 value of .816, followed by the modified Mehlich buffer method with an r2 value of .763.