bluuebunny/crossref_metadata_2025_split huggingface dataset:
P‐Type Colloidal InSb Quantum Dot Ink Enables III–V Group Bulk‐Heterojunction Shortwave Infrared (SWIR) Photodetector
Authors: Jee Seungin , Si Min‐Jae , Choi Jae‐Hwan , Kim Dongeon , Kim Changjo , Yang Dongsoo , Baek Se‐Woong 
Published: March 2024

AbstractInfrared (IR) optoelectronics have become important owing to their various applications, such as recognition, autonomous driving, and quantum communications. In particular, detection beyond 1400‐nm wavelength in the shortwave IR (SWIR) spectrum (i.e., 1550 nm) is important for eye safety, and long‐range communication. Recently, group III–V (InAs or InSb) colloidal quantum dots (CQDs) have attracted considerable interest due to their broadband optical tunability and toxic‐elements (Pb and Hg)‐free properties. Herein, a new approach is developed to synthesize highly monodispersed InSb CQD by employing the continuous injection method, which enables facile optical bandgap tuning at a SWIR wavelength of up to 0.9 eV. Furthermore, solution ligand exchange using halides and thiolates results in effective passivation of the InSb CQD surface and renders a stable p‐type CQD ink. Finally, bulk heterojunction (BHJ) structure is demonstrated using n‐type InAs:p‐type InSb CQDs, which exhibits broad absorption up to 1600 nm, and a sixfold higher responsivity compared with the pristine InSb CQD device due to the efficient charge transport in BHJ CQD solids.
Enhanced Renal Carcinoma Treatment via Synergistic Photothermal/Photodynamic Therapy Using Hittorf's Phosphorus‐Decorated Polymeric Carbon Nitride Heterostructure
Authors: Guan Chen , Li Chenyu , Yang Chengyu , Yang Dongjiang , Zhang Lixue , Xu Lingyu , Liu Ke , Zhang Ningxin , Li Tianyang , Song Zhuo , Che Lin , Wang Yanfei , Zhang Liwei , Li Daohao , Zhu Yukun , Xu Yan 
Published: March 2024

AbstractNanostructured heterojunctions offer a promising solution to overcome the limitations of narrow absorption spectra, limited penetration depths, and potential harm to healthy cells in phototherapy for clear cell renal cell carcinoma (ccRCC) treatment with nanomaterials. In this study, a heterostructure (PCN@HP) by decorating Hittorf's phosphorus nanorods onto biocompatible polymeric carbon nitride (PCN), enabling excitation by NIR light is designed. Compared with PCN and HP alone, the synthesized heterostructure generated localized heat upon broad absorption spectra of irradiation, boosting charge migration and separation, generating cytotoxic reactive oxygen species (ROS). Then, via in vitro and in vivo experiments, it is confirmed that the NIR‐mediated PCN@HP heterojunction is a safe and effective approach for synchronous photothermal and photodynamic therapy treatment of ccRCC. Collectively, the PCN@HP heterojunction holds great potential as a non‐invasive synergistic, dual‐mode therapeutic nanomedicine for efficient tumor nano‐therapy.
A Cell‐Permeable Photosensitizer for Selective Proximity Labeling and Crosslinking of Aggregated Proteome
Authors: Feng Huan , Zhao Qun , Zhao Nan , Liang Zhen , Huang Yanan , Zhang Xin , Zhang Lihua , Liu Yu 
Published: March 2024

AbstractIntracellular proteome aggregation is a ubiquitous disease hallmark with its composition associated with pathogenicity. Herein, this work reports on a cell‐permeable photosensitizer (P8, Rose Bengal derivative) for selective photo induced proximity labeling and crosslinking of cellular aggregated proteome. Rose Bengal is identified out of common photosensitizer scaffolds for its unique intrinsic binding affinity to various protein aggregates driven by the hydrophobic effect. Further acetylation permeabilizes Rose Bengal to selectively image, label, and crosslink aggregated proteome in live stressed cells. A combination of photo‐chemical, tandem mass spectrometry, and protein biochemistry characterizations reveals the complexity in photosensitizing pathways (both Type I & II), modification sites and labeling mechanisms. The diverse labeling sites and reaction types result in highly effective enrichment and identification of aggregated proteome. Finally, aggregated proteomics and interaction analyses thereby reveal extensive entangling of proteostasis network components mediated by HSP70 chaperone (HSPA1B) and active participation of autophagy pathway in combating proteasome inhibition. Overall, this work exemplifies the first photo induced proximity labeling and crosslinking method (namely AggID) to profile intracellular aggregated proteome and analyze its interactions.
Dynamics of Analog Switching Behavior in Thin Polycrystalline Barium Titanate
Authors: Andreeva Natalia V. , Ryndin Eugeny A. , Petukhov Anatoliy E. , Vilkov Oleg Y. , Al‐Saman Amgad A. 
Published: March 2024

AbstractEngineering of interfaces and point defects in ferroelectric memristors is an efficient way for manipulating the resistive switching effects of mixed ionic‐electronic nature. However, an interplay between the defects, interfacial properties, and ferroelectric polarization as well as their influence on the resistance state tuning are yet to be revealed. By considering the memristive device built on a thin polycrystalline BaTiO3film, a drift‐diffusion model of non‐stationary processes is developed. The model is based on Poisson and continuity equations solved numerically and accounts for various transport mechanisms for electrons, holes, and oxygen vacancies. Comparing simulated resistive effects with experimental data taken in a wide temperature range, it is shown that an appearance of the analog resistive switching cannot be explained solely by oxygen‐ionic transport. Investigated switching dynamics claims the oxygen vacancies redistribution to be responsible for the analog character of the switching at the prevalence of the electron hopping transport. Crucially, the required dynamics of the vacancies redistribution is achieved only in a narrow range of their mobility. These results can be used in designing the ferroelectric memristors for nonvolatile multilevel memory devices satisfying the requirements that arise at the stages of their integration into neuromorphic architectures.
Plasmonic group 4 transition metal carbide interfaces for solar‐driven desalination
Authors: Margeson Matthew J. , Atwood Mark , Monfared Yashar Esfahani , Dasog Mita 
Published: March 2024

AbstractTo combat the dwindling supply of freshwater, solar‐driven desalination using plasmonic nanomaterials has emerged as a promising and renewable solution. Refractory plasmonic carbide nanomaterials are exciting candidates that are inexpensive and chemically robust but have not been widely explored. Herein, plasmonic carbide interfaces made of TiC, ZrC, and HfC nanoparticle aggregates loaded onto to a mixed cellulose ester (MCE) membrane were explored to gain insight into their solar‐vapor generation and desalination potential. Desalination using Atlantic Ocean water under 1 sun intensity yielded rates of 1.26 ± 0.01, 1.18 ± 0.02, and 1.40 ± 0.01 kg m−2 h−1, with efficiencies of 86%, 80%, and 96% for TiC, ZrC, and HfC, respectively. Carbide interfaces showed good stability and effectively removed heavy metal ions and salt from solutions with concentrations up to 35%. PVA hydrogel based TMC evaporators afforded rates of 3.31 ± 0.03 and 3.22 ± 0.03 kg m−2 h−1 for TiC and ZrC, respectively. The HfC‐PVA interface afforded a high solar desalination rate of 3.69 ± 0.04 kg m−2 h−1, corresponding to an efficiency of 97% under 1‐sun illumination. The hydrogel evaporators also retained their strong salt rejection action over time.
Defining autopolyploidy: Cytology, genetics, and taxonomy
Authors: Lv Zhenling , Addo Nyarko Charles , Ramtekey Vinita , Behn Helen , Mason Annaliese S. 
Published: March 2024

AbstractAutopolyploidy is taxonomically defined as the presence of more than two copies of each genome within an organism or species, where the genomes present must all originate within the same species. Alternatively, “genetic” or “cytological” autopolyploidy is defined by polysomic inheritance: random pairing and segregation of the four (or more) homologous chromosomes present, with no preferential pairing partners. In this review, we provide an overview of methods used to categorize species as taxonomic and cytological autopolyploids, including both modern and obsolete cytological methods, marker‐segregation‐based and genomics methods. Subsequently, we also investigated how frequently polysomic inheritance has been reliably documented in autopolyploids. Pure or predominantly polysomic inheritance was documented in 39 of 43 putative autopolyploid species where inheritance data was available (91%) and in seven of eight synthetic autopolyploids, with several cases of more mixed inheritance within species. We found no clear cases of autopolyploids with disomic inheritance, which was likely a function of our search methodology. Interestingly, we found seven species with purely polysomic inheritance and another five species with partial or predominant polysomic inheritance that appear to be taxonomic allopolyploids. Our results suggest that observations of polysomic inheritance can lead to relabeling of taxonomically allopolyploid species as autopolyploid and highlight the need for further cytogenetic and genomic investigation into polyploid origins and inheritance types.
Lipid composition micronutrient and cellular antioxidant properties of borage seed oil from eight provinces in China
Authors: Cui Ru , You Yue , Chen Chuang , Zhang Wenjing , Zhang Yiren , Li Yun , Zhang Le , Zhang Hui , Jin Qingzhe , Wu Gangcheng , Wang Xingguo 
Published: March 2024

AbstractBorage seed oil (BSO; Borago officinalis L.) has great medicinal and nutritional potential owing to its bioactive components. In this study, we compared the lipid composition, micronutrient content, free radical scavenging capacities, and cellular antioxidant and antiproliferative activities of BSO from eight provinces in China. The Gansu sample had the highest levels of γ‐linolenic acid, accounting for 18.66%. We detected more than 17 triacylglycerols in BSO. Among micronutrients, δ‐tocopherol and Δ5‐avenasterol were the main components of tocopherol and phytosterol, respectively. The highest cellular antioxidant activity values were found in the Shanxi and Gansu samples; the concentration cytotoxicity 50% values were higher than 200 mg/mL, and the median effective dose ranged from 18.34 ± 0.52 to 70.65 ± 1.76 mg/mL. In addition, we tested the free radical scavenging capacity of BSO and found significant differences in antioxidant capacity between samples from different regions, and the Gansu sample had a better antioxidant capacity.
Importance of emulsifiers in chocolate industry: Effect on structure, machinability, and quality of intermediate and final products
Authors: Toker Omer Said , Ozonuk Seyma , Gunes Recep , Icyer Necattin Cihat , Rasouli Haniyeh Pirouizan , Konar Nevzat , Palabiyik Ibrahim , Altop Cengiz 
Published: March 2024

AbstractMany parameters are effective in obtaining optimum rheological and sensory properties in chocolate. Lecithin, ammonium phosphatides (AMP), and less commonly glycerol monopalmitate (GMP) are typically used as emulsifiers to achieve the desired viscosity in chocolate. In addition to these emulsifiers, polyglycerol polyricinoleate (PGPR) is used as a complement to regulate the yield value in chocolate. In this review, the properties of these additives, their interactions with each other, and the mechanism of their structural improvement functions in chocolate production are discussed. Depending on the type and amount of emulsifier, adjustments can be made to the flow behavior of molten chocolate, textural, melting character, tempering and tempering index, color and other properties of the chocolate. In addition to the use of emulsifiers, other parameters such as particle size distribution, moisture and fat content should also be taken into account, which can affect all these quality parameters. In this regard, the correct selection of the type of emulsifiers used in chocolate production and their combined usage rates will ensure that the demands of producers and consumers are met.
Copper Oxide Anchored Carbon Nanofibers: A Versatile Platform for Multiplex Detection of Antibiotics, Heavy Metals and Pesticides
Authors: Mishra Smriti , Budania Yashmeen , Tyagi Ankit , Pratap Singh Sheelendra , Kumar Pradip , Singh Shiv 
Published: March 2024

AbstractElectrochemical sensors offer promising prospects for real–time pollutant monitoring. In this study, copper oxide–dispersed graphitic carbon nanofibers (CuO−CNFs) grown via chemical vapour deposition were employed as a robust platform for detecting a variety of environmental pollutants. This array–based sensor adeptly identifies three different classes of analytes, i. e., antibiotics (chloramphenicol (CP) and tylosin tartrate (TT)), heavy metals (cadmium (Cd) and lead (Pb)), and pesticides (quinalphos (QP) and imidacloprid (IP)). Electron collection is facilitated by a glassy carbon electrode, while various physico–electrochemical methods delve into the properties of CuO−CNFs. The CuO−CNF–modified GCE array rapidly discerns (<15 sec) a broad linear range: 1–20 ppm for CP, 1–13.33 ppm for TT, 0.66–11.66 ppm for Cd, 20–33.33 ppm for Pb, 1.6–11.6 ppm for QP, and 5–25 ppm for IP, boasting quantification limits of 1.0, 1.0, 0.66, 20.0, 1.6, and 5.0 ppm for CP, TT, Cd, Pb, QP, and IP, respectively. Notably, this sensor achieves simultaneous identification of mixed analytes, including CP and TT, Cd and Pb, and QP and IP, within real tap water. Furthermore, the electrochemical sensor exhibits robustness; heightened sensitivity, selectivity, and stability; a swift response; and impressive reproducibility in detecting CP, TT, Cd, Pb, QP, and IP within aqueous samples. Consequently, this array–based electrochemical sensor has emerged as a rapid and simultaneous detection tool for diverse pollutant residues in surface and groundwater samples.
The perfect combination to win the competition: Bringing sustainability and customer experience together
Authors: Ünal Umut , Bağcı Rıfgı Buğra , Taşçıoğlu Mertcan 
Published: March 2024

AbstractUnderstanding the connection between how consumers perceive sustainability and how they experience the offered products or services can make a big difference for companies to stay ahead of the competition. When companies work to make their products and services align with what their customers value, like being eco‐friendly and socially responsible, it may not only draw in new customers but also make the existing ones stick around. Using behavioral reasoning theory, we attempt to explore the impacts of perceived benefits and skepticism on attitude toward sustainability and the moderating role of customer experience on the relationship between these variables and loyalty. Findings (n = 660) showed that attitude toward sustainability mediates the relationship between perceived benefits, skepticism, and customer loyalty. Furthermore, our findings highlighted that customer experience moderates the relationship between attitude toward sustainability and loyalty. The details of the moderation analysis suggest that cognitive, affective, physical, and social experiences have a stronger effect than sensory experiences in reinforcing the impact of perceived benefits and attitude on consumer loyalty in a sustainability context. The article concludes with implications and research directions for further investigation.
Exploring the mechanisms of kaempferol in neuroprotection: Implications for neurological disorders
Authors: Nezhad Salari Amir Mohammad , Rasoulizadeh Zahra , Shabgah Arezoo Gowhari , Vakili‐Ghartavol Roghayyeh , Sargazi Ghasem , Gholizadeh Navashenaq Jamshid 
Published: March 2024

AbstractKaempferol, a flavonoid compound found in various fruits, vegetables, and medicinal plants, has garnered increasing attention due to its potential neuroprotective effects in neurological diseases. This research examines the existing literature concerning the involvement of kaempferol in neurological diseases, including stroke, Parkinson's disease, Alzheimer's disease, neuroblastoma/glioblastoma, spinal cord injury, neuropathic pain, and epilepsy. Numerous in vitro and in vivo investigations have illustrated that kaempferol possesses antioxidant, anti‐inflammatory, and antiapoptotic properties, contributing to its neuroprotective effects. Kaempferol has been shown to modulate key signaling pathways involved in neurodegeneration and neuroinflammation, such as the PI3K/Akt, MAPK/ERK, and NF‐κB pathways. Moreover, kaempferol exhibits potential therapeutic benefits by enhancing neuronal survival, attenuating oxidative stress, enhancing mitochondrial calcium channel activity, reducing neuroinflammation, promoting neurogenesis, and improving cognitive function. The evidence suggests that kaempferol holds promise as a natural compound for the prevention and treatment of neurological diseases. Further research is warranted to elucidate the underlying mechanisms of action, optimize dosage regimens, and evaluate the safety and efficacy of this intervention in human clinical trials, thereby contributing to the advancement of scientific knowledge in this field.
Long‐term function of a novel autologous transcatheter pulmonary heart valve implant in an adult animal model
Authors: Kiekenap Jonathan , Sun Xiaolin , Hao Yimeng , Steitz Marvin , Breitenstein‐Attach Alexander , Emeis Jasper , Berger Felix , Schmitt Boris 
Published: March 2024

AbstractBackgroundCurrent heart valve implants entail major disadvantages in the treatment for younger patients or those with congenital heart defects.AimEvaluation of novel transcatheter pulmonary valve implant made from autologous pericardium with natural crosslinking agent in an in vitro setup and in vivo animal modelMethodsValves were tested in a pulse duplicator according to ISO‐standard 5840. For in vivo studies computer tomography was performed to measure sheep's native pulmonary valve dimensions. Pericardium was harvested by thoracotomy, personalized implants were manufactured and deployed in pulmonary valve position of the same sheep. Every 3 months implant functionality was evaluated by intracardiac echocardiography, intracardiac pressure measurements and cardiac magnetic resonance imaging (cMRI). Implants were explanted for macroscopic and histological examination.ResultsIn vitro experiments showed compliance with regulatory requirements in terms of valve opening and insufficiency. Five sheep successfully received an autologous valve implant. Two animals had to be euthanized due to trauma sustained in the stable. Long‐term valve function was excellent in three out of four animals with median implant cMRI regurgitation fraction of 9% (n = 4) at 3 months, 8% (n = 3) at 6, 8% (n = 3) at 9, 12% (n = 3) at 13, 8% (n = 2) at 17% and 8% (n = 2) at 20.5 months after implantation. Despite good adherence to neighboring tissue and endothelization, histological assessment revealed some signs of degeneration.ConclusionTranscatheter pulmonary valve implants showed promising function for up to 20.5 months encouraging research to further improve this approach.
Impact of preprocedural left ventricular systolic function on the safety and durability of percutaneous coronary intervention
Authors: Velagaleti Raghava S. , Harrell Camden , Michalski Justin , Lefèvre Thierry , Windecker Stephan , Slagboom Ton , Saito Shigeru , Koolen Jacques , Waksman Ron , Kandzari David E. 
Published: March 2024

AbstractBackgroundPercutaneous coronary intervention (PCI) is considered less safe in patients with reduced ejection fraction (EF), an impression based on older data. Whether the safety and durability of contemporary PCI are different in patients with reduced EF compared with normal EF patients is unknown.MethodsPatients from the BIOFLOW II, IV and V clinical trials were grouped as normal EF (≥50%) and reduced EF (30%–50%). Using multivariable logistic regression and cox proportional hazards regression, we determined relations of EF category with procedural safety (a composite of cardiac death, myocardial infarction, stroke and urgent coronary artery bypass grafting within 30 days of PCI) and target lesion failure (TLF; comprising cardiac death, target vessel myocardial infarction, target vessel revascularization within 1 year of PCI) respectively. In sensitivity analyses, we regrouped patients into EF < 45% and ≥55% and repeated the aforementioned analyses.ResultsIn 1685 patients with normal EF (mean age 65 years; 27% women; mean EF 61%) and 259 with low EF (mean age 64 years; 17% women; mean EF 41%), 101 safety and 148 TLF events occurred. Compared with patients in the normal EF group, those with reduced EF had neither a statistically significant higher proportion of safety events, nor a higher multivariable‐adjusted risk for such events. Similarly, patients with reduced EF and normal EF did not differ in terms of TLF event proportions or multivariable‐adjusted risk for TLF. The results were similar in sensitivity analyses with EF groups redefined to create a 10% between‐group EF separation.ConclusionPCI safety and durability outcomes are similar in patients with mild‐moderately reduced EF and normal EF.
Successful heart transplantation from a COVID‐19‐positive donor: A clinical case report
Authors: Meidani Mohsen , Moradi Maryam , Ghiasvand Fereshteh , Alijani Neda 
Published: March 2024

Key Clinical MessageDespite the acceptable results in patients receiving organs from COVID‐19‐positive donors, more extensive studies over a longer period are still needed for more accurate conclusions.AbstractOrgan transplantation is a major concern during the current COVID‐19 pandemic worldwide. The use of COVID‐19‐positive organ donors has raised widespread concerns in the field of transplantation. In this study, we characterized the outcome of a heart transplant from an organ donor positive for COVID‐19.
A 23‐year‐old patient with bilateral hypoplastic thumbs and toes: A case report
Authors: Hamsho Suaad , Sleiay Mouhammed , Alaswad Mohammed , Alsmodi Hasan , Al‐Hakeem Khaled 
Published: March 2024

Key Clinical MessageHowever, it is noteworthy that certain patients with minor functional limitations in their hand may have experienced undiagnosed thumb hypoplasia during their childhood years. These individuals may have successfully adapted to their condition without seeking medical intervention and may express a preference for nonintervention (as in this case).AbstractThumb hypoplasia is a congenital underdevelopment of the thumb, accounting for 5%–15% of congenital hand disorders. It occurs equally among both genders and can affect both thumbs. The condition is categorized using Blauth's classification with Type I being the mildest form. We report a 23‐year‐old Syrian male presented with a bilateral restriction in opposition movement when using a pen or razor. Clinical examination and x‐ray imaging revealed a bilateral Type I hypoplastic thumb with bilateral minimal hypoplasia of the toes. Despite the surgical treatment options available, the patient opted not to undergo surgery due to his adaptation to his condition. Hypoplastic thumb Type I is a congenital condition characterized by underdevelopment of the thumb. Bilateral thumb hypoplasia with toes hypoplasia is extremely rare. A full systemic evaluation should be done due to its associations with other syndromic manifestations and treatment options are discussed concerning the best functional outcomes and patient preferences.