bluuebunny/crossref_metadata_2025_split huggingface dataset:
Desarrollo profesional continuo centrado en las necesidades de aprendizaje
Authors: Riganti Paula , Alurralde Micaela B. , Ganiele María N. , Sigal Tamara V. , Gavoto Leticia , Terceiro Diego R. , Arceo Dolores 
Published: April 2024

Introducción: hace tiempo que nuestra institución ofrece actividades de educación médica continua a sus médicos, pero hasta el momento nunca habían sido evaluadas formalmente. Nos propusimos evaluar el programa académico actual y rediseñar la propuesta educativa basándonos en las necesidades de aprendizaje (NA) de los participantes.Desarrollo: en 2021 evaluamos la satisfacción con el programa académico vigente y exploramos NA utilizando tres métodos de recolección: encuesta, grupos focales y un cuestionario. Con esta información diseñamos una nueva propuesta de desarrollo profesional continuo (DPC) que implementamos en 2022 y evaluamos a fines de ese mismo año mediante una nueva encuesta.Resultados: durante 2021, 90 de un total de 148 médicos (61%) respondieron la encuesta, 16 respondieron el cuestionario y 73 participaron de grupos focales. Los participantes mencionaron diversas áreas en las que les gustaría formarse y habilidades fundamentales que hacen a la práctica del médico de familia. Algunas actividades del programa actual eran valoradas y respondían bien a las NA, pero otras eran criticadas por la poca utilidad y relevancia para la práctica. Con esta información diseñamos una nueva propuesta educativa para 2022, proponiendo 12 ejes temáticos con actividades didácticas, orientadas a la práctica, donde cada participante elegía en qué formarse. A fines de 2022, 58 de 148 médicos (39%) respondieron la encuesta de evaluación. La mayoría consideró que las actividades les resultaron útiles y estuvieron motivados para participar por el interés en el tema y la disponibilidad horaria. Hubo buena participación en las actividades, aunque también aumentó la carga de trabajo de los equipos docentes al aumentar la oferta.Conclusión: la nueva propuesta brinda mayor flexibilidad, accesibilidad y autonomía en la formación continua y fue bien valorada. El próximo desafío es seguir evaluando cómo podemos mantener la satisfacción y calidad del programa sin sobrecargar a los equipos docentes.
Synthesis, Characterization, Antioxidant and Biological Activities of Polyglucose Based Hydrazides and their Metal Nano Composites
Authors: Sahar Hina , Gilani Muhammad Rehan Hasan Shah , Hussain Mazhar , Athar Muhammad , Naqvi Syed Ali Raza , Xu Guobao 
Published: April 2024

The interaction of carbon (C) and nitrogen (N) single, double, and triple bonds with an aliphatic and aromatic carbon skeleton is widely used for medications and polymer synthesis. Many scientists have employed these compounds as target structures to determine their diverse chemical synthesis and use in various fields. The synthesis of polyglucose-hydrazide metal nanocomposites is a novel area of chemistry research. Polyglucose metal nanocomposites are widely used for drug delivery to target cancer and other lethal diseases. The major interests of this research were to synthesize, characterize, and find out the antibacterial properties of hydroxyl groups present in polyglucose-hydrazide metal nanocomposites. These nanocomposites were synthesized by acidification, esterification, and hydrazination of glucose and mixing of metal nanoparticles with polyglucose, respectively. The characterization of proposed nanocomposites was done by using scanning electron microscopy (SEM) and, energy dispersive X-Ray (EDX) spectroscopy. The biological activities of polyglucose-hydrazides cobalt, silver, and iron nano-composites were tested against Xanthomonas campestris malvacearum (a bacterial strain) by agar disc diffusion method. Amongst all, polyglucose-hydrazides cobalt nanocomposite yielded the highest antibacterial activity. Silver and iron nanocomposites also showed good activity. These results indicate that the antibacterial activities of metal nanoparticles are remarkably enhanced by combining with polyglucose hydrazide. These polyglucose-hydrazide metal nanocomposites have great potential as biocompatible antibacterial agents.
Occupational exposure to organic solvents and the risk of developing testicular germ cell tumors (TESTIS study): Effect of combined exposure assessment on risk estimation
Authors: Guth Margot , Pilorget Corinne , Lefevre Marie , Coste Astrid , Danjou Aurélie , Dananché Brigitte , Praud Delphine , Pérol Olivia , Daudin Myriam , Clarotti Marie-Ange , Lattes Stéphanie , Bouillon Céline , Paul Adèle , Schüz Joachim , Bujan Louis , Olsson Ann , Fervers Béatrice , Charbotel Barbara ,   The TESTIS study group
Published: April 2024

OBJECTIVES: Etiological factors of testicular germ cell tumors (TGCT) remain largely unknown, but a causal role of occupational exposures to solvents has been suggested. Previous studies analyzing these exposures reported discordant results, potentially related to exposure assessment methods. The aim of this study was to investigate the role of occupational exposure to solvents on the risk of developing TGCT among young men.
METHODS: This study examined occupational exposures to solvents and TGCT risk based on the lifetime work histories of 454 cases and 670 controls, aged 18–45 years, of the French national TESTIS case–control study. Solvent exposure was estimated using: (i) exposure assignment by job-exposure matrix (JEM) and (ii) JEM combined with self-reported exposure data from specific questionnaires (SQ) and expert assessment (EA). Odds ratios (OR) and 95% confidence intervals (CI) were estimated using conditional logistic regression models.
RESULTS: Both approaches (JEM and JEM+SQ+EA) showed a consistent association between TGCT and trichloroethylene exposure (exposed versus not exposed; JEM=OR 1.80 [95% confidence interval (CI) 1.12–2.90] and JEM+SQ+EA= OR 2.59 (95% CI 1.42–4.72). Both approaches also observed positive associations with ketone esters and fuels & petroleum-based solvents.
CONCLUSION: The results suggest that some organic solvents might be involved in the pathogenesis of TGCT among occupationally exposed men. The combined use of JEM+SQ+EA seemed to limit misclassification by considering individual exposure variability and is, therefore, an appealing approach to assess occupational exposures in epidemiological studies.
Tratamiento psicofarmacológico de la esquizofrenia en la población infantojuvenil: estado del arte
Authors: Iveli María Florencia 
Published: April 2024

La esquizofrenia es una patología crónica y grave que se caracteriza por la presencia de delirios, alucinaciones, síntomas negativos, desorganización del pensamiento y del comportamiento. Si bien su prevalencia en menores de 13 años es muy baja, aumenta sustancialmente durante la adolescencia. Cuando se desarrolla antes de los 18 años se denomina esquizofrenia de inicio precoz y representa del 12 al 33 % del total de los individuos con este trastorno. Existen fármacos como el haloperidol, risperidona, paliperidona, aripiprazol, olanzapina, quetiapina, brexpiprazol y lurasidona aprobados por la Food and Drug Administration (FDA) para el tratamiento de la esquizofrenia en adolescentes. Sin embargo, a excepción del haloperidol, todas las indicaciones farmacológicas que se realizan para tratar este trastorno en menores de 13 años resultan “off label” (fuera de las indicaciones de la ficha técnica). Si bien esta práctica no se encuentra prohibida, conlleva riesgos adicionales. En el siguiente trabajo se revisará la evidencia disponible acerca del uso de los antipsicóticos para el tratamiento de la esquizofrenia en la población infantojuvenil, con el objetivo de realizar una síntesis de la información con aplicabilidad clínica.
Preparing Business Students for Success in the 4th Industrial Revolution
Authors: Prater Rebecca , Predki Nicole 
Published: April 2024

The fast-changing, technology-dominate Fourth Industrial Revolution is upon us. Unfortunately, our current education system is based on training compliant workers to perform repetitive tasks required for the industrial revolution of the early 1900’s. Today, employers are looking for skills such as complex problem solving, critical thinking, creativity, people management, emotional intelligence, divergent thinking, and cognitive flexibility. It is our responsibility as educators to make sure our students are taught in a manner that supports their success and helps them benefit from the exponential changes occurring in our world, one that fosters complex problem solving, critical thinking, creativity, and cognitive flexibility. We develop these skills in students by creating an environment where they are called to use their imagination, experiences, and unique perspective while applying the taught concepts. Asking open-ended questions such as “How are you going to do it?” results in unique and infinite answers that are not right or wrong, encouraging students to take risks and be creative. In this paper, the authors present several ways to activate this creative, divergent thinking process.
“Trend” Statement Use in the Orthopaedic Literature
Authors: Luzzi Andrew J. , Czerwonka Natalia , Rogalski Brandon , Knudsen Michael L. , Levine William N. 
Published: April 2024

Introduction:
For research to effectively guide clinical decision making, appropriate interpretation of data is paramount. The P-value is a useful tool for guiding the interpretation of data. However, despite its utility, the P-value is not without limitations. Of particular concern is the use of “trend statements” to describe non-statistically significant findings, a practice which introduces subjectivity and variability into data interpretation and can lead to the drawing of undue conclusions.

Methods:
An audit of original research articles published from January 2022 to December 2022 in four high-impact orthopaedic journals was conducted. The selected journals were queried to identify instances in which a non-statistically significant result was labeled as a “trend.” The use of trend statements and associated information was recorded and analyzed.

Results:
One thousand two hundred sixty articles were included in the analysis. 81 articles (6.4%) included a trend statement to describe a non-statistically significant result. Only two articles (2.5%) formally defined what constituted a trend. In 28.8% of cases, the associated P-value was > 0.10.

Discussion:
Trend statements are used to describe non-statistically significant findings with moderate frequency in the orthopaedic literature. Given the potentially misleading effects of trend statements, efforts should be made to mitigate their use. If trend statements are to be used, attention should be paid to defining what constitutes a “trend”, explicitly acknowledging the lack of statistical significance of the finding to which the trend statement refers, and avoiding drawing undue conclusions from non-statistically significant data.
Carboxysomes: Green Solutions for Sustainable Agriculture and Renewable Energy
Authors: Jawad Ahmed Fridoon 
Published: April 2024

Carboxyomes are emerging as potential tools in the sustainable agriculture and biofuel production. They are proteinaceous organelles that are distributed in different species of photosynthetic bacteria and archaea and are significantly involved in carbon fixation. They enable the organisms to thrive in diverse environmental conditions and enhance the efficacy of photosynthesis. They have shown promising potential to address challenging regarding global food security, climate change and renewable energy.
These nanocompartments encapsulate Ribulose-1,5-bisphosphate carboxylase/oxygenase (RuBisCO), an enzyme that catalyzes the first step of the Calvin-Benson-Bassham cycle that is a key pathway in carbon fixation. These specialized structures concentrate CO2 around RuBisCO ad shield it from the competing oxygen, thereby optimizing the efficiency of photosynthetic process and minimize wasteful photorespiration. The photosynthetic organisms having carboxysomes are therefore ideal candidates for sustainable agriculture as they are able to thrive in the harsh conditions such as low CO2 concentrations, water scarcity and high temperatures.
They are recently being studied for enhancing the productivity and yield of crops. Efforts are being exerted to introduce carboxysome shell proteins and RuBisCO enzymes into crop genomes. Researchers are aiming to create plants with the ability to efficiently capture and utilize CO2 for photosynthesis. These genetically modified crops can potentially increase crop yields, improve water and nutrient efficiency significantly. Moreover, these carboxysomal transgenes are also able to enhance the resilience of GM plants to different environmental stressors such as drought and heat, and ultimately contribute to global food security and sustainable agriculture.
In addition to their applications in agriculture, carboxysomes hold promise for biofuel production as well, as they are capable of carbon fixation. They have enabled researchers to engineer photosynthetic organisms to produce renewable fuels such as ethanol, biodiesel and hydrogen. Furthermore, nanobioreactors that are based on carboxysomes can contribute protectively against climate change as they have the potential to mitigate greenhouse gas emissions by capturing CO2 from industrial emissions and converting it into valuable bioproducts.
This approach represents a promising avenue to address global challenges of food insecurity, climate crisis and rapidly declining non-renewable energy sources. If leveraged appropriately, these nanocompartments can significantly contribute in paving a way for more sustainable and resilient future.
The Coral Chronicles: Climate Crisis and Its Implications on the Global Coral Reefs
Authors: Sheikh Nadeem 
Published: April 2024

The coral reefs are one of the most devastating causalities that is often overlooked as our planet grapples with the continually progressing crisis of climate change. They are often addressed as the rainforests of the sea and are hubs of biodiversity that support a one-fourth of all marine species even though they only cover less than one percent of the ocean floor. Not only are they inhabiting countless marine creatures, they are also a crucial food an income source to the millions of people worldwide. Alas! These vibrant underwater ecosystems are being pushed to the brink of collapse due the relentless onslaught of climate change.
Consider the Great Barrier Reef, off the coast of Australia, where extensive coral bleaching events are occurring due to rising sea temperatures [1]. The threat of ocean acidification has jeopardized the coral reef in the Maldives and is potentially affecting the country economically which is based on the tourism and fisheries. Likewise, Caribbean Sea is facing disease outbreak and coral bleaching. Philippines is home to some of the most diverse coral reefs in the world but, climate change, overfishing and coastal development is threatening these natural ecosystems. Apart from these, Seychelles and Mauritius in the Indian Ocean and the Coral triangle in the Southeast Asian region are also at stake due to these environmental stressors [2].
In the face of these challenges, many governments, NGOs and local communities have united to conserve these global reefs. Different Marine Protected Areas (MPAs) have been developed to mitigate overfishing and habitat destruction and protect the coral reefs [3]. Moreover, many techniques have been developed to restore the degraded coral ecosystems and enhance their resilience, including Coral Transplantation and Artificial Reef Structures. These initiatives have created the hope that the vibrant coral reefs will eventually recover in face of the existing environmental crises.
However, we cannot overstate that the current situation is dire and nothing short of a global calamity. It is our moral obligation that we protect and preserve these natural wonders for future generations. If we do not take immediate action to curb the emission of greenhouse gases and fight against the climate change, we risk losing these underwater ecosystems right in front of our eyes. It is our choice and the stakes could not be higher.
Identyfikacja czynników motywujących do nauki studentów kierunków technicznych.
Authors: Wachnicka Wiktoria , Wojtowicz Alicja 
Published: April 2024

Celem artykułu jest identyfikacja czynników motywujących studentów studiów technicznych do nauki, w obecnej rzeczywistości post-pandemicznej. Część teoretyczna przybliża definicje motywacji oraz odnoszące się do nich koncepcje. W niniejszej pracy zaadoptowano klasyczne koncepcje motywacji takie jak piramida potrzeb. A.Maslowa, dwuczynnikowa teoria F.I.Herzberha oraz teoria XIY do rozpoznania postawy wobec uczenia się studentów kierunków technicznych. Dla osiągniecia celu przeprowadzono badanie na grupie docelowej 83 studentów uczelni technicznych, w postaci ankiety odnoszącej się do wyżej wspomnianych teorii. Otrzymane wyniki pozwoliły na wskazanie czynników motywujących i potrzeb jakie muszą zostać spełnione by student czuł się zmotywowany.
Hoito syytteen sijaan -toimintamallin ­arviointitutkimus: Monialaista yhteistyötä nuorten ­huumausaineiden käytön ­ehkäisemiseksi
Authors: Lilja Taru , Ristikari Tiina , Niemelä Mika 
Published: April 2024

Hoito syytteen sijaan on Lapin poliisin ja sosiaali-, terveys- ja nuorisopalvelujen yhteistyömalli,jonka tavoitteena on ehkäistä lasten ja nuorten huumausaineiden käyttöä.
Käyttörikoksesta ensimmäisen kerran kiinni jääneelle alle 25-vuotiaalle tarjotaan psykososiaalista hoitoa.
Mallia ollaan kehittämässä yhtenäisemmäksi, vaikuttavammaksi ja kuntien rakenteisiin paremmin integroitavaksi.
Tässä artikkelissa esitellään kehittämisen tueksi toteutettu laadullinen haastattelututkimus ja ­systemaattinen kirjallisuuskatsaus. Niiden perusteella mallia verrataan samankaltaisiin ­kansainvälisiin toimintamalleihin.
Päätelmänä on, että monialaisen toimintamallin onnistuminen edellyttää säännöllistä ­yhteyden­pitoa toimijoiden välillä. Yhteiseen tavoitteeseen ja yhteistyöhön sitoutuminen on tärkeää.
Monialaisesti organisoitujen toimintamallien kehittämisessä toimijoiden yhteistyön laadullinen ­arviointi on varteenotettava vaihtoehto perinteisille vaikuttavuustutkimuksille.
TCM-ryhmänhallintamenetelmän ­käyttöönotto – laadullinen monitieteinen pilottitutkimus opettajien kokemuksista
Authors: Maunula Minna , Granlund Kati , Harju-Luukkainen Heidi , Palosaari Oona 
Published: April 2024

Kun ryhmässä on esimerkiksi käyttäytymisellään reagoivia oppilaita, tarvitaan nopeaa puuttumistasekä moniammatillisen ja monitieteisen näkökulman hyödyntämistä.
TCM-ryhmänhallintamenetelmän tavoitteena on tukea oppilaan sosioemotionaalista kehitystä, ­parantaa opettajan ja oppilaan vuorovaikutusta sekä vahvistaa koulun ja kodin yhteistyötä.
Opettajan ryhmänhallintataidot heijastuvat myönteisesti kaikkiin luokan oppilaisiin.
Opettajan myönteinen viestintä koteihin voi edistää vuorovaikutusta ja helpottaa hankalien asioiden hoitoa.
TCM-menetelmän implementointi kouluyhteisöön vaatii tukea.
Kollegiaaliset kokemukset ja uudistuneet ryhmänhallintataidot vahvistavat opettajan työssä jaksamista.
Vaikuttavuustutkimus: Meta-analyysista lisää voimaa tulosten tulkinnan tueksi
Authors: Hinkka-Yli-Salomäki Sanna 
Published: April 2024

Artikkeli on jatkoa Kasvun tuki -aikakauslehdessä julkaistulle Vaikuttavuustutkimus-artikkelisarjalle:– Vaikuttavuustutkimus: Satunnaistettu vertailukoe tulee suunnitella huolella (2/2021)– Vaikuttavuustutkimus: Satunnaistetun vertailukokeen laadukkaan raportoinnin edellytykset (1/2022)– Vaikuttavuustutkimus: Miten arvioida harhaa satunnaistetuissa vertailukokeissa? (2/2022)– Vaikuttavuustutkimus: Mitä tulee huomioida analysoitaessa satunnaistetun vertailukokeen aineistoa? (1/2023)

Meta-analyysi on tilastollinen menetelmä, jonka avulla yhdistetään kvantitatiivisesti systemaattisen katsauksen tutkimukset.
Meta-analyysi yhdistää useiden tutkimusten tulokset parhaaksi arvioksi näiden tutkimusten tuloksista.
Satunnaistettujen vertailukokeiden meta-analyyseissa hyvä tutkimuskysymys määrittelee osallistujat, interventiot, vertailut ja vasteet (Participants, Interventions, Comparisons, Outcomes eli PICO).
Meta-analyysissa on monta vaihetta: 1) tutkimuskysymysten määrittäminen2) kirjallisuustietokantojen läpikäynti3) tutkimusten valinta ja tietojenhaku4) efektikokojen yhdistäminen5) heterogeenisyyden tarkastelu 6) meta-analyysin tulosten raportoiminen.
Yksilökohtaiseen dataan ja osajoukkoanalyyseihin perustuvat meta-analyysit soveltuvat parhaiten kohdennettujen interventioiden tarkasteluun.
Innovación en Arquitectura
Authors: Pérez Nanclares Carlos Mario , Del Blanco García Federico Luis 
Published: April 2024

Esta investigación analiza el papel de ciertas redes sociales como herramientas educativas en el aprendizaje de la arquitectura, específicamente en talleres de proyectos enfocados en el diseño paramétrico, un método vinculado estrechamente con la conceptualización y aplicación del diseño computacional.
La investigación se centra en la pregunta de si estas experiencias digitales pueden igualar la interacción social en los talleres de diseño, un aspecto considerado esencial por varios expertos en educación para el desarrollo de habilidades técnicas y creativas.
Representation of investigation results of microplastics on sandy beaches—accumulation rate and abundance in the entire study site
Authors: Asakura Hiroshi 
Published: April 2024

Long-term microplastics (MPs) environmental pollution trends cannot be understood only by investigating their presence on beaches. Without estimating MPs for the entire beach, comparisons between multiple beaches cannot be made. In this study, Nagasaki Prefecture was selected as the study site, we measured MPs accumulation rate to express the MPs pollution trend and weighted the measurement results to enable comparison of MPs content among multiple sandy beaches. The MPs accumulation rate in the study site was measured by periodic investigation at fixed spots. The average in the supratidal zone was 1.5 ± 0.9 mg-MPs/(m2-sand⋅ d) (n = 15). The weighting of the MPs content in hot spots and non-hot spots by their respective areas enabled us to obtain the representative value and the dispersion of the MPs content in the entire study site. The MPs contents in the three beaches were 298 ± 144, 1,115 ± 518, and 4,084 ± 2,243 mg-MPs/(m2-sand), respectively. Using these values, it is possible to compare the MPs contents of multiple beaches.
Fluorescence patterns and diversity of hydrozoans from Bocas del Toro, Panama
Authors: Beckmann Lara M , Vincent Bridget A , De León Alexandra , Masterman Jessica , Lau Emily S , Haddock Steven HD 
Published: April 2024

Many metazoans contain molecules capable of fluorescence, the absorption and re-emission of light. Since the anatomical distribution, or patterning, of these molecules is variable across taxa, patterns of fluorescence may serve as a powerful diagnostic tool in taxonomy and ecology. However, species-specific fluorescence patterns among marine invertebrates are poorly understood. Here, we show that hydrozoans have diverse fluorescence patterns, which may result from molecules that are produced intrinsically or obtained from dietary sources. We surveyed hydrozoans including siphonophores, hydromedusae, and hydroids across 5 orders from pelagic and benthic marine environments in Bocas del Toro, Panama. Our findings show that fluorescence patterns are highly prevalent and may vary across hydrozoan species and throughout development. Most of the examined hydrozoan taxa exhibited some form of fluorescence, with variation observed between life stages and body parts. Fluorescence was documented in 88% of hydromedusae (Leptothecata, Anthoathecata, Limnomedusae and Narcomedusae), 50% of hydroid, and 75% of siphonophore taxa that were observed in this study. Our results illustrate how fluorescence patterns may serve as a useful diagnostic tool to explore marine biodiversity, highlighting the need for further documentation of fluorescence patterns across marine diversity and research into the molecules that underlie this phenomenon.