bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pediatric hidradenitis suppurativa publication trends: 2012 to 2022
Authors: Park Sarah E. , Shih Terri , Dagenet Caitlyn , Hogeling Marcia , Hughes Meagan , Gillenwater Justin , Shi Vivian Y. , Hsiao Jennifer L. 
Published: February 2024

AbstractThere is a paucity of bibliometric data on pediatric‐focused hidradenitis suppurativa (HS) publications. To better characterize research trends in pediatric HS and gaps in literature, we systematically searched PubMed between 2012 and 2022 for publications on pediatric HS and collected data on study design, topic, country, and level of evidence. Of 109 articles that met inclusion criteria, less than half (44/109, 40.4%) were high level of evidence studies; the most common study types were case reports/series (41/109, 37.6%) and cross‐sectional studies (25/109, 22.9%), and the most common study topics were HS treatments (44/109, 40.4%), comorbidities (20/109, 18.3%), and clinical presentation (14/109, 12.8%). Although there has been expansion of the pediatric HS literature in recent years, our study highlights the need for larger prospective studies and trials to improve our ability to optimally manage pediatric HS patients and identify predictors of disease progression and treatment response.
Efficacy of parent–child interaction therapy for children born premature
Authors: Matano Miyuki , Kurane Koyuru , Wakabayashi Kei , Yada Yukari , Kono Yumi , Tajima Toshihiro , Osaka Hitoshi , Monden Yukifumi 
Published: February 2024

AbstractBackgroundPremature children are known to be at a high risk of developing behavioral problems. This study examined the effectiveness of parent–child interaction therapy (PCIT) in reducing behavioral problems in young children born premature.MethodsThe study included 18 child–parent pairs with children born at less than 35 weeks of gestation (range: 23–34 weeks, median: 31.0 weeks) and aged 27–52 months (median: 38.0 months). They were assigned to either the PCIT group (n = 7) or the non‐PCIT group (n = 11) based on maternal desire for treatment. The study was designed to examine the effects of PCIT. Specifically, the Eyberg Child Behavior Inventory (ECBI) intensity score, ECBI problem score, and Parenting Stress Index Short Form (PSI‐SF) scores were compared before treatment and after 6 months.ResultsIn the PCIT group, the mean ECBI intensity score was 135.7 (SD = 13.5; T‐score = 64) at baseline and 90.1 (SD = 15.5; T‐score = 46) at post‐assessment, the mean ECBI problem score was 9.8 (SD = 1.9; T‐score = 54) at baseline and 4.4 (SD = 3.1; T‐score = 44) at post‐assessment, the mean PSI‐SF total score was 60.1 (SD = 4.8; 95%tile) at baseline and 49.6 (SD = 5.6; 85%tile) at post‐assessment, showing a significant improvement (ECBI intensity scores: p < 0.001, d = 2.03; ECBI problem scores: p < 0.001, d = 1.94; PSI‐SF total scores: p = 0.004, d = 0.86). On the other hand, none of the scores showed significant change in the non‐PCIT group.ConclusionsThe PCIT can be considered as a potential treatment option for behavioral problems in young children born premature.
The role of viruses in oral mucosal lesions
Authors: Dommisch Henrik , Schmidt‐Westhausen Andrea Maria 
Published: February 2024

AbstractThe mucosa of the oral cavity is exposed to a large number of different microorganisms such as archaea, bacteria, fungi, parasites, and viruses. Among those, viruses cause specific infections, which can easily be transmitted from one person to another. The infectious route may not only include patients and their relatives but also the dental professional team. Thus, a wide knowledge regarding specific viral infections is crucial for the daily routine. Signs and symptoms of oral viral infections can be completely absent or develop into a pronounced clinical picture, so that early detection and information determine the further course of the infection and its influence on other inflammatory diseases, such as periodontitis, as well as the safety of family members and the social environment. As the clinical manifestation of viral infections may be highly variable leading to heterogenous mucosal lesions it is, in most cases, mandatory to differentiate them by specific microbiological tests in addition to clinical examination procedures. This article will give an overview of the role of viruses infecting the oral mucosa, and in addition, describe their clinical manifestation and management.
Clinical utility of depression measures and symptoms: Implications for suicide risk assessment in high risk, resource limited youth populations
Authors: Chapman‐Hilliard Collette , Pelham Tanisha , Mollo Victoria , Henry Paulette , Miller Benjamin , Yankura Joe , Denton Ellen‐ge 
Published: February 2024

AbstractObjectiveSuicide risk for youth in resource‐ limited settings has been largely underrepresented in the literature and requires targeted examination of practical ways to address this growing public health concern. The present study focuses on the clinical utility of depression risk assessment tools addressing how and for whom suicide prevention intervention is most beneficial within a low‐middle‐income‐country, high suicide risk youth sample.MethodsYouth who reported a previous suicide attempt versus those who did not were criterion to test the validity of depression and hopelessness symptom assessment tools. We used item analyses to identify depressive symptom endorsements that most informed youth suicide risk, which will better equip rural practitioners for targeted intervention and monitoring of youth with an already high risk for suicide.ResultsFindings demonstrated that practitioners may target symptoms of social anhedonia, depressed mood, concentration disturbance, feelings of worthlessness, sleep disturbance, and fatigue for suicide prevention‐intervention efforts among high‐risk youth.ConclusionsStudy implications are for clinicians' use of the BDI‐II and CES‐D for depression symptom identification and suicide risk monitoring in settings with limited mental health infrastructure.
Stories of country women: Advancing feminist intersectionality for climate change adaptation in Australia
Authors: Casey Sarah , Crimmins Gail , McIntyre Joanna , O'Sullivan Sandy 
Published: February 2024

AbstractDrought has always had a historical presence in ‘rural’ Australia and is predicted to intensify in frequency and duration due to climate change. We argue here that the creeping havoc drought visits upon humans, animals and ecosystems in an Australian context is a form of ‘slow violence’ . Such harm and hardship are often obscured because they are more challenging to conceptualise and symbolise than sudden, spectacle‐creating disasters. Furthermore, in Australia, it is often obscured because of discursive prioritising of ‘urban’ centres. We resist the ‘invisibility’ of this form of slow violence, applying the concept of slow violence in combination with intersectionality and a relational mode of interviewing to analyse data from 27 interviews undertaken across 3 years with a range of women in drought‐declared regions of South‐West Queensland, Australia. We centre the voices of Aboriginal women as leaders in this space, as well as settler women who are often overlooked in the settler narrative of working the land. In doing so, we interrogate external constructions of ‘the rural’ and bring recognition to stories and knowledges of women who live with its daily and yearly impacts.
Race and democratic decline in the United States: How minority population growth affects election administration
Authors: Coll Joseph A. , Maltby Elizabeth , Rocha Rene R. 
Published: February 2024

AbstractObjectivesWe ask whether counties with growing black and Latino populations have reduced the number of poll workers and polling sites. We argue that the association between changing racial demographics and election infrastructure has been exacerbated by the release of certain jurisdictions from the Voting Rights Act's (VRA) “preclearance” requirement under Section 5.MethodsRelying on data from the 2016 and 2018 Election Administration and Voting Survey and demographic data from the American Community Survey, we conduct a multilevel linear regression on a sample of roughly 4000 counties.ResultsWe find that counties respond to changes in the Latino population, though not changes in the black population, by reducing access to election resources. This relationship is especially pronounced in areas formerly covered by Section 5 of the VRA.ConclusionsGiven the importance of polling places and workers for in‐person voting, our findings raise serious concerns for racial equality in election access and influence.
Reassessing pseudosluicing in Austronesian
Authors: Middleton John 
Published: February 2024

AbstractPseudosluicing diagnostics have played an important role in wider debates about sluicing. Sluicing is the term used to describe the deletion of an embedded clausal constituent, which leaves only a wh‐phrase overt. Genuine sluicing requires syntactic or semantic identity between the sluiced clause and its antecedent, contrasting with pseudosluicing, in which pro‐drop creates the appearance of a sluice but no identity is required. The underlying structure of sluicing in several Austronesian languages has been argued to be pseudoclefts, which involve a nominal wh‐predicate and a headless relative clause argument. Both Malagasy and Nukuoro have been analysed as having pseudocleft sluicing, and on the basis of this, claims about the type of identity required in sluicing have been made. Both analyses rely on diagnostics that rule out the possibility of pseudosluicing. This paper reexamines the pseudosluicing diagnostics used for Malagasy and Nukuoro and concludes that they have been insufficiently controlled for. This is supported by data from Madurese showing that pseudosluicing diagnostics are inconclusive in these Austronesian languages. Language‐internal support is needed for such diagnostics, especially as they play an important role in the conclusions drawn from Austronesian languages on the wider identity requirement for sluicing. Three language‐specific diagnostics are given which are successfully able to identify pseudosluicing in Madurese.
The OsDIR55 gene increases salt tolerance by altering the root diffusion barrier
Authors: Xue Baoping , Duan Wen , Gong Luping , Zhu Dongmei , Li Xueying , Li Xuemei , Liang Yun‐Kuan 
Published: February 2024

SUMMARYThe increased soil salinity is becoming a major challenge to produce more crops and feed the growing population of the world. In this study, we demonstrated that overexpression of OsDIR55 gene enhances rice salt tolerance by altering the root diffusion barrier. OsDIR55 is broadly expressed in all examined tissues and organs with the maximum expression levels at lignified regions in rice roots. Salt stress upregulates the expression of OsDIR55 gene in an abscisic acid (ABA)‐dependent manner. Loss‐function and overexpression of OsDIR55 compromised and improved the development of CS and root diffusion barrier, manifested with the decreased and increased width of CS, respectively, and ultimately affected the permeability of the apoplastic diffusion barrier in roots. OsDIR55 deficiency resulted in Na+ accumulation, ionic imbalance, and growth arrest, whereas overexpression of OsDIR55 enhances salinity tolerance and provides an overall benefit to plant growth and yield potential. Collectively, we propose that OsDIR55 is crucial for ions balance control and salt stress tolerance through regulating lignification‐mediated root barrier modifications in rice.
Lisdexamfetamine dimesylate (Vyvanse) toxicosis in a dog
Authors: Martindale Danielle M. , Haraschak Jenica L. , Thiel Andrew J. , Samuelson Jonathan P. , Buchweitz John P. 
Published: February 2024

AbstractObjectiveTo describe the presentation, management, and postmortem examination findings in a dog with confirmed lisdexamfetamine dimesylate (LDX) toxicosis.Case SummaryA 3‐year‐old female neutered mixed breed dog initially presented with neurological signs suspected to be secondary to LDX toxicosis. The dog was treated as typical for amphetamine toxicoses but developed severe respiratory and cardiovascular signs throughout their hospitalization. The progression of the cardiopulmonary signs led to cardiopulmonary arrest, for which CPR was unsuccessful. Postmortem examination exhibited severe hemorrhage throughout multiple organ systems. Toxicology testing confirmed the presence of unaltered LDX and its metabolite, amphetamine.New or Unique Information ProvidedThis is the first case report documenting a severe progression of clinical signs and postmortem examination findings in a case of confirmed LDX toxicosis in a dog. Although the patient did not survive treatment, postmortem examination and microscopic evaluation of tissues allowed visualization of the extent of systemic pathophysiology. With prompt treatment, the prognosis of amphetamine toxicosis in dogs is generally considered good; however, this case report demonstrates a severe case in which even prompt and appropriate treatment did not prevent mortality. This suggests a need to establish negative prognostic indicators for which to monitor in cases of amphetamine toxicosis. Finally, this report is also unique in the fact that the LDX toxicosis was confirmed using a toxicological analysis technique not previously described clinically in dogs.
Daily blood flow restriction does not preserve muscle mass and strength during 2 weeks of bed rest
Authors: Fuchs Cas J. , Hermans Wesley J. H. , Nyakayiru Jean , Weijzen Michelle E. G. , Smeets Joey S. J. , Aussieker Thorben , Senden Joan M. , Wodzig Will K. H. W. , Snijders Tim , Verdijk Lex B. , van Loon Luc J. C. 
Published: February 2024

AbstractWe measured the impact of blood flow restriction on muscle protein synthesis rates, muscle mass and strength during 2 weeks of strict bed rest. Twelve healthy, male adults (age: 24 ± 3 years, body mass index: 23.7 ± 3.1 kg/m2) were subjected to 14 days of strict bed rest with unilateral blood flow restriction performed three times daily in three 5 min cycles (200 mmHg). Participants consumed deuterium oxide and we collected blood and saliva samples throughout 2 weeks of bed rest. Before and immediately after bed rest, lean body mass (dual‐energy X‐ray absorptiometry scan) and thigh muscle volume (magnetic resonance imaging scan) were assessed in both the blood flow restricted (BFR) and control (CON) leg. Muscle biopsies were collected and unilateral muscle strength (one‐repetition maximum; 1RM) was assessed for both legs before and after the bed rest period. Bed rest resulted in 1.8 ± 1.0 kg lean body mass loss (P < 0.001). Thigh muscle volume declined from 7.1 ± 1.1 to 6.7 ± 1.0 L in CON and from 7.0 ± 1.1 to 6.7 ± 1.0 L in BFR (P < 0.001), with no differences between treatments (P = 0.497). In addition, 1RM leg extension strength decreased from 60.2 ± 10.6 to 54.8 ± 10.9 kg in CON and from 59.2 ± 12.1 to 52.9 ± 12.0 kg in BFR (P = 0.014), with no differences between treatments (P = 0.594). Muscle protein synthesis rates during bed rest did not differ between the BFR and CON leg (1.11 ± 0.12 vs. 1.08 ± 0.13%/day, respectively; P = 0.302). Two weeks of bed rest substantially reduces skeletal muscle mass and strength. Blood flow restriction during bed rest does not modulate daily muscle protein synthesis rates and does not preserve muscle mass or strength.
imageKey points
Bed rest, often necessary for recovery from illness or injury, leads to the loss of muscle mass and strength. It has been postulated that blood flow restriction may attenuate the loss of muscle mass and strength during bed rest.
We investigated the effect of blood flow restriction on muscle protein synthesis rates, muscle mass and strength during 2 weeks of strict bed rest.
Blood flow restriction applied during bed rest does not modulate daily muscle protein synthesis rates and does not preserve muscle mass or strength.
Blood flow restriction is not effective in preventing muscle atrophy during a prolonged period of bed rest.
An Electrochemical-Thermal Coupling Model Based on Two-Factor Parameter Modification for Lithium-Ion Battery
Authors: Chen Lin , Zhao Mingsi , He Manping , Chen Deqian , Ding Yunhui , Pan Haihong 
Published: February 2024

Abstract
The accurate establishment of battery model can improve the design reliability and reduce the design risk, which provides an important basis for the research of battery. First, the key parameters of the Li-ion battery model are identified by the least square method based on the full-battery equivalent circuit model of the single-particle impedance spectrum, and the diffusion coefficient and exchange current density under different temperatures and SOC conditions are calculated. At the same time, the one-dimensional thermal rate model is used as the heat source of the three-dimensional model, and the mean temperature T of the three-dimensional model is calculated by using Fourier's law, and T is fed back to the one-dimensional model as the key parameter to modify the conductivity, diffusion coefficient, and exchange current density, and a semi-empirical electrochemical-thermal coupling model with two-factor parameter modification is established. Finally, the model is verified by the temperature field distribution and discharge voltage curve at different discharge rates. The maximum temperature difference is less than 3.1 °C, and the maximum voltage difference error is less than 0.131 V. The results show that the improved model can accurately reflect the influence of temperature on the model parameters, and has high accuracy in the estimation of battery terminal voltage and SOC.
Power Loss and Damage Behavior of Gears Operating Under Loss of Lubrication
Authors: Morhard Bernd , Paschold Constantin , Lohner Thomas , Stahl Karsten 
Published: February 2024

AbstractGeared turbofans need to withstand loss of lubrication due to inevitable off-design conditions. Additionally, the loss of lubrication specifications that have to be fulfilled are getting stricter. For a loss of lubrication event, today's geared turbofans are equipped with secondary oil supply systems. Their omission would reduce space and weight and, consequently, carbon emissions. However, this requires geared transmissions to withstand loss of lubrication events. In order to enable this, knowledge of the power loss and damage behavior of gears under loss of lubrication is required first. In this study, power loss and bulk temperature measurements of test gears under loss of lubrication on an FZG gear efficiency test rig are presented. Hertzian pressures in the pitch point up to 1723 N/mm2 and circumferential speeds up to 20 m/s were considered. The experimental results show the characteristics of increasing power loss and bulk temperatures under loss of lubrication depending on load and speed. At moderate operating conditions, no damage occurs within 20 s under loss of lubrication, whereas a load increase results in slight scuffing, and a speed increase results in severe scuffing. Oil centrifugation has a strong effect on the loss of lubrication performance. Additional experiments under reduced quantity lubrication demonstrate the impact of the remaining oil on the survivability of gears facing the loss of lubrication.
Delayed gametocyte clearance in
Plasmodium vivax
malaria is associated with polymorphisms in the cytochrome P450 reductase (CPR)
Authors: Salazar Yanka Evellyn Alves Rodrigues , Louzada Jaime , Puça Maria Carolina Silva de Barros , Guimarães Luiz Felipe Ferreira , Vieira José Luiz Fernandes , Siqueira André Machado de , Gil José Pedro , Brito Cristiana Ferreira Alves de , Sousa Tais Nobrega de 
Published: February 2024

ABSTRACT

Primaquine (PQ) is the main drug used to eliminate dormant liver stages and prevent relapses in
Plasmodium vivax
malaria. It also has an effect on the gametocytes of
Plasmodium falciparum
; however, it is unclear to what extent PQ affects
P. vivax
gametocytes. PQ metabolism involves multiple enzymes, including the highly polymorphic CYP2D6 and the cytochrome P450 reductase (CPR). Since genetic variability can impact drug metabolism, we conducted an evaluation of the effect of CYP2D6 and CPR variants on PQ gametocytocidal activity in 100 subjects with
P. vivax
malaria. To determine gametocyte density, we measured the levels of
pvs25
transcripts in samples taken before treatment (D0) and 72 hours after treatment (D3). Generalized estimating equations (GEEs) were used to examine the effects of enzyme variants on gametocyte densities, adjusting for potential confounding factors. Linear regression models were adjusted to explore the predictors of PQ blood levels measured on D3. Individuals with the
CPR
mutation showed a smaller decrease in gametocyte transcript levels on D3 compared to those without the mutation (
P
= 0.02, by GEE). Consistent with this, higher PQ blood levels on D3 were associated with a lower reduction in
pvs25
transcripts. Based on our findings, the
CPR
variant plays a role in the persistence of gametocyte density in
P. vivax
malaria. Conceptually, our work points to pharmacogenetics as a non-negligible factor to define potential host reservoirs with the propensity to contribute to transmission in the first days of CQ–PQ treatment, particularly in settings and seasons of high
Anopheles
human-biting rates.