bluuebunny/crossref_metadata_2025_split huggingface dataset:
Ribosomes modulate transcriptome abundance via generalized frameshift and out-of-frame mRNA decay
Authors: Zhang Yujie , Nersisyan Lilit , Fürst Eliska , Alexopoulos Ioannis , Huch Susanne , Bassot Claudio , Garre Elena , Sunnerhagen Per , Piazza Ilaria , Pelechano Vicent 
Published: March 2024

SummaryCells need to adapt their transcriptome to quickly match cellular needs in changing environments. mRNA abundance can be controlled by altering both its synthesis and decay. Here we show how, in response to poor nutritional conditions, the bulk of theS. cerevisiaetranscriptome undergoes -1 ribosome frameshifts and experiences an accelerated out-of-frame co-translational mRNA decay. Using RNA metabolic labelling, we demonstrate that in poor nutritional conditions, NMD-dependent degradation represents at least one third of the total mRNA decay. We further characterize this mechanism and identify low codon optimality as a key factor for ribosomes to induce out-of-frame mRNA decay. Finally, we show that this phenomenon is conserved from bacteria to humans. Our work provides evidence for a direct regulatory feedback mechanism coupling protein demand with the control of mRNA abundance to limit cellular growth and expands the functional role of mRNA quality control.
Hemispheric multi-dimension features extraction analysis based on decoupled representation learning
Authors: Su Yuwei , Wang Sifeng , Zhang Xiaoyu , Lan Min , Zhong Suyu 
Published: March 2024

AbstractThe predominant approach in investigating brain structural asymmetry relies on predefined regions of interest, assessing variations between homologous brain regions through a single indicator, which is local, univariate, and relative. In response to this challenge, we employ decoupled representation learning from deep learning to extract hidden features containing hemisphere-specific information at a hemispheric systemic level. This novel approach enables a global and multivariate analysis of brain structural asymmetry. Our findings indicate a significant association between left-hemisphere-specific hidden features and language-related behavioral metrics, as well as a correlation between right-hemisphere-specific hidden features and social-related behavioral metrics. Tensor-based Morphometry results find the impact of left-hemisphere-specific features on the left inferior frontal sulcus within Broca’s area, a crucial region for language processing. Additionally, right-hemisphere-specific features influenced the right rostral hippocampus, a region implicated in emotion regulation and spatial navigation. The findings from Neurosynth indicate that significant regions caused by left-hemisphere-specific features are correlated with language, while significant regions caused by right-hemisphere-specific features are associated with behaviors primarily governed by the right hemisphere. Furthermore, our study establishes a link between structural changes induced by hemisphere-specific features and several genes. Such findings demonstrate that the application of deep learning techniques allows for precise capture of hemisphere-specific information within individual hemispheres, offering a new perspective for future research on brain structural asymmetry.
Spontaneous Gap Opening and Potential Excitonic States in an Ideal Dirac Semimetal
Ta2Pd3Te5
Authors: Zhang Peng , Dong Yuyang , Yan Dayu , Jiang Bei , Yang Tao , Li Jun , Guo Zhaopeng , Huang Yong , Haobo  , Li Qing , Li Yupeng , Kurokawa Kifu , Wang Rui , Nie Yuefeng , Hashimoto Makoto , Lu Donghui , Jiao Wen-He , Shen Jie , Qian Tian , Wang Zhijun , Shi Youguo , Kondo Takeshi 
Published: March 2024

The opening of an energy gap in the electronic structure generally indicates the presence of interactions. In materials with low carrier density and short screening length, long-range Coulomb interaction favors the spontaneous formation of electron-hole pairs, so called excitons, opening an excitonic gap at the Fermi level. Excitonic materials host unique phenomena associated with pair excitations. However, there is still no generally recognized single-crystal material with excitonic order, which is, therefore, awaited in condensed matter physics. Here, we show that excitonic states may exist in the quasi-one-dimensional material Ta2Pd3Te5, which has an almost ideal Dirac-like band structure, with the Dirac point located exactly at the Fermi level. We find that an energy gap appears at 350 K, and it grows with decreasing temperature. The spontaneous gap opening is absent in a similar material Ta2Ni3Te5. Intriguingly, the gap is destroyed by the potassium deposition on the crystal, likely due to extra-doped carriers. Furthermore, we observe a pair of in-gap flat bands, which is an analog of the impurity states in a superconducting gap. All these observations can be properly explained by an excitonic order, providing Ta2Pd3Te5 as a new and promising candidate realizing excitonic states.

Published by the American Physical Society
2024
Exploring the both-and success paradox in mega construction projects: multi-dimensional assessments of paradoxical leadership, project agility and megaproject success
Authors: Zaman Umer , Florez-Perez Laura , Abbasi Saba , Nawaz Muhammad Shahid 
Published: March 2024

PurposeOrganizations are full of contradictions and leadership dilemmas. Managers often face challenges such as selecting between two contradicting options such that which one is more important can hardly be judged. To manage contradicting dynamics, today’s managers can adopt the paradoxical leadership approach. We build a theoretical model to investigate the influence of paradoxical leadership on multi-dimensional project agility (proactivity, adaptability, and resilience), and multi-dimensional project success (management, investment, and ownership success).Design/methodology/approachDrawing on survey-based data from the China–Pakistan Economic Corridor (CPEC) megaproject (N = 209), we performed covariance-based structural equation modeling to test the conceptual model.FindingsThe findings show that (1) paradoxical leadership has a significant positive impact on megaproject success, (2) paradoxical leadership has a significant positive influence on project agility, (3) project agility has a significant positive effect on megaproject success, and (4) project agility has a significant effect that mediates the link between paradoxical leadership and megaproject success. This research provides a theoretical and practical comprehension of paradoxical leadership with a new perspective on megaprojects.Originality/valueThis study provides an extension of the existing studies on paradoxical leadership and identifies the role of contradicting dynamics and their impact on multiple facets of megaproject success. It not only clarifies the relationship between paradoxical leadership and megaproject success, but also identifies the mediating role of project agility that can play an effective role in mobilizing success in megaprojects.
Climate neutrality in agriculture food supply chain: an integrated WINGS-GRID framework
Authors: Yadav Vinay Surendra , Raut Rakesh 
Published: March 2024

PurposeSubstantial pressure from civil society and investors has forced governments around the world to take climate neutrality initiatives. Several countries have pledged their nationally determined contributions towards net-zero. However, there exist various obstacles to achieving the same and the agriculture sector is one of them. Thus, this study identifies and models the critical barriers to achieving climate neutrality in the agriculture food supply chain (AFSC).Design/methodology/approachSixteen barriers are identified through a literature survey and are validated by the questionnaire survey. Furthermore, the interactions amongst the barriers are estimated through the application of the “weighted influence non-linear gauge system (WINGS)” method which considers the both intensity of influence and the strength of the barrier. To mitigate these barriers, a framework based on green, resilient and inclusive development (GRID) is proposed.FindingsThe obtained results reveal that lack of collaboration amongst AFSC stakeholders, lack of information and education awareness, and lack of technical expertise obtained a higher rank (amongst the top five) in three indicators of the WINGS method and thus are the most significant barriers.Originality/valueThis paper is the first attempt in modelling the climate neutrality barriers for the Indian AFSC. Additionally, the mitigating strategies are prepared using the GRID framework.
Master in education students' attitudes toward research at one University of Education in Myanmar
Authors: Htang Ling Kee , Hlaing Thet Htar 
Published: March 2024

PurposeThis study scrutinizes the attitudes of postgraduate students specializing in education toward research at one University of Education in Myanmar.Design/methodology/approachHaving collected data from 121 Master in Education (MEd) students in three education departments, the study validated Papanastasiou's (2014) Revised-Attitude toward Research (R-ATR) scale by performing confirmatory factor analysis (CFA). A one-way MANOVA was used to establish the significance of mean differences between groups and ANOVA was used for the same purpose among groups.FindingsThe R-ATR scale is fit with the sample (χ2/df = 1.60), and the students' attitudes toward research are favorable with mean value for research usefulness (5.98), positive research predispositions (5.55) and research anxiety (3.61), despite feeling stressed and anxious. There was a significant difference in the students' attitudes toward research regarding their departments, while no significant difference was found based on their research experience, gender and age.Practical implicationsThere should be an effective mechanism in implementing the research course and in online delivery mode, collaboration between the faculties in the process of revision and review of the research courses, effective strategies of improving research instructors' quality and also internationalization to sustain students' positive attitudes toward research and to reduce their stress and anxiety.Originality/valueThis research is empirically novel, and the initiative attempts to first use the R-ATR scale in teacher education in Myanmar.
Does lean inventory management alleviate financing constraints?
Authors: Wang Jingbin , Yao Xinyan , Zhu Xuechang , Li Baitong 
Published: March 2024

PurposeThis study explores the intricate relationship between inventory leanness, financial constraints and digital transformation in listed Chinese manufacturing firms.Design/methodology/approachUsing a large panel data collected from 2,563 Chinese listed manufacturing enterprises over the period from 2012 to 2021, this research employs the instrumental variable method combined with two-stage least squares estimators to explore the U- shaped relationship between inventory leanness and financial constraints. Furthermore, the moderating role of digital transformation is demonstrated.FindingsContrary to traditional assumptions, our research uncovers a U-shaped relationship between inventory leanness and financial constraints, indicating that excessive inventory reduction can exacerbate financial constraints. Digital transformation plays a significant moderating role, particularly in highly digitalized environments.Practical implicationsOur findings have practical significance for top managers and policymakers. We advocate for a balanced approach to lean inventory management to mitigating financial constraints. The study emphasizes the pivotal role of digital transformation in alleviating the impact of inventory leanness on financial constraints, highlighting the need for digital transformation strategies.Originality/valueThis research provides a comprehensive analysis of inventory leanness, financial constraints and digital transformation dynamics. It challenges conventional thinking by revealing the nonlinear nature of the inventory leanness–financial constraints relationship. The concept of moderation highlights the moderating effect of digital transformation. This study offers practical guidance for practitioners and policymakers.
The role of online retail website experience on brand happiness and willingness to share personal information: an SOR perspective
Authors: Banerjee Shubhomoy , Shaikh Ateeque , Sharma Archana 
Published: March 2024

PurposeThe study aims to determine the role of online retail website experience on brand happiness and willingness to share personal information using the theoretical lens of the Stimulus-Organism-Response (SOR) framework. Further, it explores the role of brand intimacy and brand partner quality in mediating the path between brand happiness and willingness to share personal information.Design/methodology/approachThis study used a cross-sectional survey design to collect data from 439 online retail consumers in India, using an online questionnaire. The data were analysed using Structural Equation Modelling in IBM Amos.FindingsThe present study found that online retail website experience is significantly related to brand happiness. The finding also supports that brand happiness was positively and significantly related to ‘consumers' willingness to share personal information. This relationship was fully mediated by brand intimacy. Brand happiness also mediated the relationship between website experience and the willingness to share personal information.Research limitations/implicationsThis study contributes to the emerging literature on brand happiness and willingness to share personal information. It establishes a central role of brand happiness as a driver and a mediator of consumers' willingness to share personal information with e-commerce retailers, extending the stimulus-organism-response framework in the context of brand happiness and willingness to share personal information. Further, the study establishes the role of website experience as a marketer (and brand) led driver of brand happiness.Practical implicationsThe results have implications for the role of the website in enhancing the consumer experience, which in turn is a driver of brand happiness. Further, managers need to promote brand happiness with the help of website experience to enable consumers’ willingness to share personal information and help organizations customize their marketing campaigns.Originality/valueThis is among the first studies to evaluate brand happiness from the perspective of an online retail website experience and consider consumers’ willingness to share personal information from a branding rather than a technological perspective. Additionally, the study introduces the SOR framework in the context of brand happiness, with website experience acting as a stimulus for consumers, resulting in brand happiness, which is mediated by brand partner quality and brand intimacy (organism), leads to consumers' willingness to share personal information with online retail brands (response).
Economic growth, structural changes and employment linkages in India
Authors: Kumar Rakesh 
Published: March 2024

PurposeIndia started economic reforms at a rapid pace to catch up the world economy by following the services-led-growth model during the post-liberalisation period. Over the years, the growing unemployment rate posits a re-look into the dynamics of growth model for wider work force participation. In this backdrop, the paper aims to examine the dynamics of structural changes in employment pattern in view of economic growth led by services-led growth model in India.Design/methodology/approachThe study employs a non-linear autoregressive model (NARDL) to examine the effect of the growth rates in three broad economic sectors namely agriculture and allied, services and industry on work force participation representing the employment opportunities in India.FindingsThe results highlight that the rapid expansion of the service sector has not occurred with enough employment opportunities by the same rate. By contrast, the growth in the industrial sector significantly creates employment opportunities in the short and long run. These results support the industry led growth model over the services for sustainable and inclusive economic growth in the country.Research limitations/implicationsThe study relies on combined labour force participation rates rather than gender-specific rates. Further, the regulatory, working conditions and economic incentives may affect the gender-specific engagement of the labour force in three broad sectors.Practical implicationsThe results offer important insight into changing patterns in employment with policy lessons. A wider workforce force participation calls for expansion of manufacturing activities through pro-industry programmes.Originality/valueThe study makes pioneer efforts to examine the dynamics of labour force participation with respect to the growth of three broad economic sectors of the Indian economy. The results provide new insights with policy implications for the changing employment pattern and policy response.
Multidimensional Q‐compensated reverse time migration using a high‐efficient decoupled viscoacoustic wave equation
Authors: Ye Zilong , Huang Jianping , Mu Xinru , Mao Qiang 
Published: March 2024

AbstractSeismic waves propagating through attenuating media induce amplitude loss and phase dispersion. Neglecting the attenuation effects during seismic processing results in the imaging profiles with weakened energy, mispositioned interfaces and reduced resolution. To obtain high‐quality imaging results, Q‐compensated reverse time migration is developed. The kernel of the Q‐compensated reverse time migration algorithm is a viscoacoustic wave equation with decoupled amplitude loss and phase dispersion terms. However, the majority of current decoupled viscoacoustic wave equations are solved using the computationally expensive pseudo‐spectral method. To enhance computational efficiency, we initiate our approach from the dispersion relation of a single standard linear solid model. Subsequently, we derive a novel decoupled viscoacoustic wave equation by separating the amplitude loss and phase dispersion terms, previously coupled in the memory variable. The newly derived decoupled viscoacoustic wave equation can be efficiently solved using the finite‐difference method. Then, we reverse the sign of the amplitude loss term of the newly derived viscoacoustic wave equation to implement high‐efficient Q‐compensated reverse time migration based on the finite‐difference method. In addition, we design a regularization term to suppress the high‐frequency noise for stabilizing the wavefield extrapolation. Forward modelling tests validate the decoupled amplitude loss and phase dispersion characteristics of the newly derived viscoacoustic wave equation. Numerical examples in both two‐dimensional and three‐dimensional confirm the effectiveness of the Q‐compensated reverse time migration based on the finite‐difference algorithm in mitigating the attenuation effects in subsurface media and providing high‐quality imaging results.
Environmental filtering governs consistent vertical zonation in sedimentary microbial communities across disconnected mountain lakes
Authors: Von Eggers Jordan M. , Wisnoski Nathan I. , Calder John W. , Capo Eric , Groff Dulcinea V. , Krist Amy C. , Shuman Bryan 
Published: March 2024

AbstractSubsurface microorganisms make up the majority of Earth's microbial biomass, but ecological processes governing surface communities may not explain community patterns at depth because of burial. Depth constrains dispersal and energy availability, and when combined with geographic isolation across landscapes, may influence community assembly. We sequenced the 16S rRNA gene of bacteria and archaea from 48 sediment cores across 36 lakes in four disconnected mountain ranges in Wyoming, USA and used null models to infer assembly processes across depth, spatial isolation, and varying environments. Although we expected strong dispersal limitations across these isolated settings, community composition was primarily shaped by environmental selection. Communities consistently shifted from domination by organisms that degrade organic matter at the surface to methanogenic, low‐energy adapted taxa in deeper zones. Stochastic processes—like dispersal limitation—contributed to differences among lakes, but because these effects weakened with depth, selection processes ultimately governed subsurface microbial biogeography.
Equity Incentive Plans and Board of Director Discretion over Equity Grants
Authors: CADMAN BRIAN , CARRIZOSA RICHARD 
Published: March 2024

ABSTRACTEquity compensation is granted out of an equity incentive plan that must be approved by shareholders and cedes discretion over equity grants to boards of directors. We predict and find that equity plan proposals give boards more discretion over grants when the firm faces greater labor market forces and more volatile stock returns. When examining votes, we find that shareholders are less likely to support plans with abnormal discretion. We also find that boards with more discretion grant more equity in response to stock price declines. Lastly, we find that boards request additional shares when their ability to grant equity is more constrained by a smaller pool of available shares, and when they plan to increase equity grants. Overall our findings illuminate how firms balance needs to respond to labor market pressure and volatile operating environments against shareholder governance and oversight of equity compensation.
Changing climate, shifting mycotoxins: A comprehensive review of climate change impact on mycotoxin contamination
Authors: Casu Alessia , Camardo Leggieri Marco , Toscano Piero , Battilani Paola 
Published: March 2024

AbstractClimate change (CC) is a complex phenomenon that has the potential to significantly alter marine, terrestrial, and freshwater ecosystems worldwide. Global warming of 2°C is expected to be exceeded during the 21st century, and the frequency of extreme weather events, including floods, storms, droughts, extreme temperatures, and wildfires, has intensified globally over recent decades, differently affecting areas of the world. How CC may impact multiple food safety hazards is increasingly evident, with mycotoxin contamination in particular gaining in prominence. Research focusing on CC effects on mycotoxin contamination in edible crops has developed considerably throughout the years. Therefore, we conducted a comprehensive literature search to collect available studies in the scientific literature published between 2000 and 2023. The selected papers highlighted how warmer temperatures are enabling the migration, introduction, and mounting abundance of thermophilic and thermotolerant fungal species, including those producing mycotoxins. Certain mycotoxigenic fungal species, such as Aspergillus flavus and Fusarium graminearum, are expected to readily acclimatize to new conditions and could become more aggressive pathogens. Furthermore, abiotic stress factors resulting from CC are expected to weaken the resistance of host crops, rendering them more vulnerable to fungal disease outbreaks. Changed interactions of mycotoxigenic fungi are likewise expected, with the effect of influencing the prevalence and co‐occurrence of mycotoxins in the future. Looking ahead, future research should focus on improving predictive modeling, expanding research into different pathosystems, and facilitating the application of effective strategies to mitigate the impact of CC.