bluuebunny/crossref_metadata_2025_split huggingface dataset:
Perlindungan Hukum Bagi Bidan yang Melakukan Tindakan Medis (Studi Kasus Rumah Sakit PKU Muhammadiyah Gombong)
Authors: Rahmad Noor , Setiyawan Deni , Indrawati Septi 
Published: March 2024

Perlindungan hukum dapat menjadi hak setiap individu, termasuk bidan. Saat ini, masih sedikit yang membahas mengenai perlindungan hukum bidan di rumah sakit PKU Muhammadiyah Gombong. Kajian ini bertujuan untuk membahas lebih dalam perlindungan hukum bagi bidan yang melakukan tindakan medis di rumah sakit PKU Muhammadiyah Gombong. Metode yang digunakan untuk mencapai tujuan tersebut yaitu penelitian hukum normatif, dengan menggunakan sumber bahan hukum primer dan sekunder. Hasil penelitian menunjukkan bidan memiliki kewenangan dalam melaksanakan tugasnya di rumah sakit. Kewenangan ini dievaluasi oleh organisasi profesi agar tidak melakukan tindakan di luar kewenangan yangberakibat pada konsekuensi hukum. Perlindungan hukum terhadap bidan dilakukan oleh Ikatan Bidan Indonesia (IBI). Apabila terjadi pelanggaran yang mengakibatkan bidan di bawah ke ranah pengadilan, maka dilakukan tinjauan oleh IBI melalui MPA IBI dan MPEB IBI. Jika bidan yang bersangkutan menjalankan standar profesi, standar pelayanan dan standar prosedur operasional, maka bantuan hukum akan diberikan oleh IBI dalam menghadapi tuntutan atau gugatan di pengadilan.
Pengaruh Konten Digital dengan Komunikasi Dialogis dan Narasi pada Emosi Krisis Negatif
Authors: Imsa Mentari Anugrah , Soegiarto Asep , Rizki Menati Fajar 
Published: March 2024

Abstrak
Perkembangan teknologi saat ini terjadi sangat pesat diikuti perkembangan proses komunikasi dimana pertukaran informasi terjadi sangat mudah terutama pada media sosial. Media sosial yang ada saat ini sangat memungkinkan pengguna untuk menuangkan pendapat, pengalaman, dan berbagai informasi lainnya atau disebut User-generated conten (UGC). UGC mengenai informasi Perusahaan tidak dapat dikendalikan oleh Perusahaan termasuk ketika dalam keadaan krisis. Oleh karena itu, penelitian ini berusaha untuk mengukur pengaruh bentuk konten yang dibuat oleh publik (konten dialogis dan narasi) terhadap emosi krisis negatif yang juga dirasakan oleh Masyarakat lain. Penelitian ini menggunakan paradigma positivis dengan pendekatan kuantitatif dengan melakukan eksperimen. Penelitian ini mengukur perubahan emosis krisis negatif Masyarakat terhadap obat sirup Sanmol yang mengalami krisis. Sampel dari penelitian ini sebanyak 118 responden yang dipilih dengan teknik purposive sampling. Hasil penelitian menunjukkan bahwa tidak ada perubahan yang signifikan emosi krisis negatif setelah mendapatkan perlakuan pada kelompok konten dialogis dan narasi.
Keywords: krisis, konten digital, komunikasi dialogis, narasi, emosi krisis negatif
La voix de ses maîtres
Authors: Roca Quentin 
Published: March 2024

Quand Théodore de Bèze, fraîchement gagné aux idées nouvelles, quitte la France pour la Suisse en 1548, il a 29 ans. Il est bientôt entouré de trois des grands noms de la Réforme, Jean Calvin à Genève, Pierre Viret à Lausanne, et Guillaume Farel à Neuchâtel. C’est à leur contact, en collaborant avec chacun d’entre eux, qu’il se prépare à prendre leur relève : à partir de 1564, à la mort de Calvin, il devient la figure de proue de la Réforme francophone. Durant les années 1550, il enchaîne les voyages et les missions, d’abord principalement autour de Lausanne, puis à Genève. Le présent article présente des témoignages d’amitié des trois vétérans pour leur benjamin, issus de leur correspondance privée en français et en latin, certains traduits en français pour la première fois. Ils illustrent les relations d’amitié qui unissent ces hommes. On les saisit ainsi dans leur humanité, leur estime mutuelle, et dans leur susceptibilité parfois.
La Beaumelle protestant : un singulier alliage de nicodémisme et de militance
Authors: Bost Hubert 
Published: March 2024

En un siècle où deux régimes de loyauté s’affrontent – l’obligation catholique qui s’impose à tous les sujets du royaume de France et le respect de la Discipline des Églises réformées du Désert qui implique de désobéir à cette obligation –, l’homme de lettres La Beaumelle (1726-1773) suit un itinéraire original sur le plan confessionnel. Ce fils d’un Cévenol protestant, élevé dans un collège catholique, s’est « converti » au protestantisme au point de vouloir devenir pasteur au Désert puis de commencer à Genève des études de théologie. Tout un pan de son activité littéraire est consacré à la défense de ses coreligionnaires, à commencer par la publication de L’Asiatique tolérant en 1748 jusqu’à sa Requête des protestants français au roi écrite pour le synode national de 1763, en passant par sa critique historiographique du Siècle de Louis XIV, ses Mémoires de Maintenon et le rôle discret mais déterminant qu’il joue dans l’affaire Calas. Mais cette appartenance protestante hautement revendiquée se combine avec une forme d’accommodement confessionnel qui se traduit d’abord par sa méfiance affichée envers les assemblées clandestines et, en 1764, par un mariage catholique célébré à Toulouse. Son «nicodémisme» pratique résulte d’une réflexion au terme de laquelle le prêtre est considéré comme un officier d’état civil. L’article présente les différentes facettes, publiques et privées, de la personnalité de La Beaumelle et s’efforce de faire apparaître les facteurs – confessionnels, mais aussi politiques et sociaux – qui jouent sur ses choix.
La formation des enseignant·e·s en prise avec les réformes : un rapport au travail (dés)ajusté pour les formateur·trice·s ?
Authors: Perez-Roux Thérèse , Françoise Christine , Torterat Frédéric 
Published: March 2024

En France, la dernière réforme de la formation initiale des enseignants (2019), mise en œuvre à la rentrée 2021, ravive les tensions entre logiques de professionnalisation, d’universitarisation et de certification. L’article tente de comprendre les reconfigurations des conditions de travail et de formation générées par la réforme puis de saisir dans quelle mesure la dérégulation des exigences institutionnelles a pu créer, chez les formateur·trice·s, une fragilisation ou un renforcement des professionnalités. Une enquête par questionnaire a été réalisée au printemps 2022 auprès de formateur·trice·s en INSPE1 sur l’ensemble du territoire (N =725). Les résultats des analyses uni et bivariées révèlent un rapport au travail (dés)ajusté et une tension renforcée entre théorie et pratique, entre croyances ou valeurs des formateurs et logiques institutionnelles. Ils éclairent, selon le statut des formateur·trice·s, les stratégies d’appropriation pour (re)donner sens à l’action.
Settlement Pattern and Periodization of the Jordanian Badia Early PPNB: A Fresh Approach to the PPNA/PPNB Transition Issue in the Southern Levant
Authors: Fujii Sumio 
Published: March 2024

Abstract. The recent excavations at Harrat Juhayra 202 and Mushash 163 in southern Jordan produced lithic assemblages marked by the predominance of Helwan-type points and the increasing use of naviform blades, which can be dated to the first half of the 9th millennium cal. BCE on the basis of a few dozen 14C dates. The upper limit dates of the two key sites are not only several centuries earlier than those of Early PPNB (hereafter EPPNB) sites in the southern Levantine Corridor but also contemporary with, or even slightly earlier than, those of EPPNB sites in the northern Levantine Corridor. Similar assemblages have been attested at Jilat 7, Abu Hudhud, Jabal `Ainab 1, and Jebel Queisa, suggesting that another EPPNB cultural entity existed in the drylands to the east of the Levantine Corridor. If so, the question is the relationship among the three EPPNB cultural entities, which is expected to shed new light on the dynamics of the PPNA/PPNB transition, a long-standing issue of the southern Levantine Neolithic archaeology. This paper approaches it from the viewpoint of the settlement pattern and periodization of the newly defined Jordanian Badia EPPNB. Research evidence suggests that the transition took place twice over, each time in a different context: first, the appearance of the Badia EPPNB (probably in a local context) at the very beginning of the 9th millennium cal. BCE and, second, the formation of the southern Levantine Corridor EPPNB (through the westward retreat of the Badia EPPNB and the southward diffusion of the northern Levantine Corridor EPPNB) in the middle of the same millennium.
La cultura legittimista nella Milano della Restaurazione
Authors: Del Corno Nicola 
Published: March 2024

Le premier numéro de la revue Biblioteca Italiana a été publié en janvier 1816. Cet article analyse en particulier les raisons qui ont poussé Vienne à prendre discrètement l’initiative de cette revue. Cela permet de comprendre les raisons de l’échec culturel, mais aussi politique, de la Restauration à Milan, dont Stendhal était également l’un des observateurs les plus aigus.
Narcisos insubmissos: autorrepresentação, identidade e diferença nas artes visuais ibero-americanas
Authors: Marconi Dieison , Vázquez-Rodríguez Lucia Gloria , Marques Bruno , Jakemiu Araújo Bortolon Flávia 
Published: March 2024

Diante da compreensão de que compartilhamos um passado histórico e sociocultural recente e similar (semiperiférico, ditatorial, colonial, cristão, monoteísta patriarcal), o que as artes ibero-americanas teriam a dizer sobre as ficções dominantes e com que ferramentas estéticas e dissensuais fariam frente a um consenso policialesco de gênero, sexualidade, raça e classe social? Que cenas, gestos e rostos, mesmo que transitórios, ambíguos e relacionais, poderiam perturbar determinados regimes policialescos não apenas de raça, gênero e classe, mas também perturbar as próprias ficções dominantes no campo das artes?
Com este número, pretendemos analisar então as operações discursivas e estéticas que ocorrem quando são as subjetividades subalternas que representam a si mesmas, em vez de serem retratadas a partir do olhar de um Outro hegemônico que frequentemente procura coisificá-las, dominá-las e observá-las de uma distância que não contamine sua subjetividade.
Prediction of the Efficacy of Radiotherapy in Head-and-neck Tumors Patients by Dosiomics and Radiomics
Authors: Liu Xi , Zhan Ning , Zou Jinhua , Liu Zhongqiang , Deng Zhenxiang , Yi Jinling 
Published: March 2024

Background:
The purpose is to investigate the efficacy of distant metastasis (DM) and locoregional recurrences (LRs) prediction through radiomics and dosimics in head-and-neck cancer (HNC) cases.

Methods:
The cases of HNC were obtained from The Cancer Imaging Archive. For the radiomics model, the features were extracted from the pretreatment computed tomography image by the pyradiomics, then the condensed features were selected as the clinically related features by the Boruta method. Finally, the random forest was used to construct the DM and LR prediction model by inputting those condensed features. For the dosiomics model, the features were extracted from the 3-dimensional dose distribution from radiation treatment plans. The radiomics and dosiomics condensed features were utilized to training and validate the prediction model’s performance. The area under the curve (AUC) value and receiver operating characteristic (ROC) curve were used to assess and compare these models.

Results:
Seven related features were extracted by the Boruta algorithm, which included one radiomics and two dosiomics features for the DM; two radiomics and two dosiomics features for the LR. Independent training and validation of the prediction and prognostic performance of the model have been observed. The roc-AUC values of the training model for the Rmodel and Dmodel were 0.793 and 0.797, 0.657 and 0.650 for the DM and LR; the roc-AUC values of the validation model for the Rmodel and Dmodel were 0.733 and 0.767, 0.646 and 0.6 for the DM and LR. The roc-AUC values of the training and validation for the radiomics and dosiomics integration model were 0.772 and 0.7, 0.792 and 0.762 for the DM and LR, respectively.

Conclusion:
Integration of radiomics and dosiomics prediction model can benefit LR in the radiotherapy patient of the head-and-neck squamous cell carcinoma, so the dosiomics should not be neglected for the related investigations.
Use of Lactoferrin Supplement as an Efficient Antioxidant to Ameliorate the Effects of Mercury-induced Oxidative Stress in Male Wistar Rats
Authors: Al Zharani Mohammed Mousa , Almuqri Eman Abdullah , Ahmed Mohammed Mubarak , Aljarba Nada Hamad , Rudayni Hassan Ahmed , Yaseen Khadija Nasser , Alkahtani Saad Hussin , Nasr Fahd Ahmed , Al Doaiss Amin Abdullah , Al eissa Mohammed Saad 
Published: March 2024

Background:
The present study was carried out to test the antioxidant activity of lactoferrin as a dietary supplement to alleviate the effects of oxidative stress induced by mercury toxicity. Hematological and biochemical assays were employed to evaluate the ameliorating effects of lactoferrin.

Methods:
Sixty male Wistar rats were allotted randomly and equally into three groups; animals in Group 1 served as untreated control, animals in Group 2 were administered orally with mercuric chloride (HgCl2) at the dose of 6 mg/kg bw/day, and animals in Group 3 were administered with HgCl2 at the same dose and orally dosed with lactoferrin (400 mg/kg bw/day). Hematological indices (erythrocytic and total leukocytic counts, hemoglobin concentration%, and packed cell volume, (PCV%), and biochemical parameters (serum and homogenates of liver and kidney tissues) were assessed in all animals. Serum and tissue homogenate levels of total thiols, glutathione (GSH), catalase, and total antioxidant capacity (TAC) represented the antioxidant markers. The oxidation markers were represented by H2O2 and malondialdehyde (MDA).

Results:
Compared to the untreated control group, animals in Group 2 (administered with HgCl2) exhibited significantly increased levels of serum enzymes (alanine transferase (ALT), aspertate transferase (AST), and alkaline phosphatase), urea, blood urea nitrogen, creatinine, H2O2, and MDA. These animals showed significantly decreased levels of erythrocytic and total leukocytic counts, hemoglobin concentration, PCV%, total proteins, total thiols, GSH, catalase, and TAC. The hematological and biochemical changes were comparatively reversed toward the control levels in animals of Group 3 (administered with HgCl2 and orally dosed with lactoferrin). The reversed levels of hematological and biochemical parameters were significantly different compared to Group 2.

Conclusions:
Based on the encountered amelioration of the assayed hematological and biochemical parameters in animals treated with HgCl2 and given lactoferrin, it could be concluded that lactoferrin as a dietary supplement might function as an efficient antioxidant to alleviate the oxidative stress induced by mercury toxicity.
Current Status of Drug-resistant Patterns of Gram-positive Clinical Isolates Collected from Renowned Diagnostic Centers of Dhaka, Bangladesh
Authors: Ferdous Mehjabin , Jabin Tasnim , Islam Shafiqul , Sarker Md. Mofaser Rahman , Rahman Sunjida , Esrat Ayesha , Mahmud Al , Hossain Md. Ifrat , Alam Seemi Tasnim , Uddin Md. Aftab 
Published: March 2024

Background:
Antimicrobial resistance is a serious concern and life threat in public health globally. Gram-positive clinical isolates are one of the leading etiological agents showing drug resistance traits. This study aimed to detect the antimicrobial resistance pattern of clinically isolated Gram-positive bacterial isolates collected from various renowned diagnostic centers of Dhaka city, Bangladesh.

Methods:
A laboratory-based cross-sectional study was conducted at the Microbiological Laboratory of the Department of Microbiology, Stamford University Bangladesh. A total of 104 clinical specimens (wound swab, pus, blood, urine, ear discharge, nasal swab, sputum, nipple discharge, breast milk, catheter tip, umbilical swab, and throat swab) from different age groups were collected from some renowned diagnostic centers of Dhaka city for analyzing the cultural and drug sensitivity patterns from January 2023 to April 2023. According to the study plan, only the Gram-positive bacteria were collected and transported to the laboratory of the Department of Microbiology, Stamford University Bangladesh following WHO guidelines, and the antimicrobial susceptibility tests were carried out by Kirby–Bauer disk diffusion method and the results were interpreted as per CLSI guidelines, 2022.

Results:
This study highlights the presence of Staphylococcus aureus (65.4%), Streptococcus spp. (23.1%), and Enterococcus spp. (11.5%) as causative agents of Gram-positive bacterial infections from overall 104 clinical specimens. Most of our isolates were found multidrug-resistant. For S.
aureus isolates, cefixime (100%); for Streptococcus spp., doxycycline (95.83%); and for Enterococcus spp., amoxicillin (100%), cefixime (100%), colistin (100%), and cotrimoxazole (100%) were found to be the most ineffective drug when compared to other antibiotics.

Conclusion:
Our study portrayed the remarkable antibiotic resistance feature of Gram-positive bacterial isolates which is a matter of public health concern. It is necessary to carry out a continuous assessment of antibiotic sensitivity patterns of resistant Gram-positive bacteria; otherwise, it will become an uncontrollable problem not only in Bangladesh but also worldwide in the near future.
Identification of Invasive Filamentous Mold Isolates Using DNA Sequencing: Experience of a Clinical Laboratory in a Resource-limited Setting
Authors: Irfan Seema , Zeeshan Mohammad , Ghanchi Najia , Jabeen Kausar , Zafar Afia 
Published: March 2024

Background:
Correct identification of clinically significant mold is becoming critical and cannot be relied only on phenotypic methods; hence, there is a dire need to develop an algorithm of workflows and capacity for molecular identification. This study shares the experience of DNA sequencing for invasive mold identification isolated and compared with phenotypic identification.

Methods:
This study was conducted at the microbiology laboratory, Aga Khan University, Karachi, Pakistan, and the Mycotic Disease Branch, Centers for Disease Control and Prevention, USA. Filamentous molds isolated from clinical specimens during January 2012–April 2013 were initially identified through phenotypic characteristics. Pan-fungal polymerase chain reaction targeting the internal transcribed spacer region of the ribosomal cistron and the D1/D2 domains of the 28S ribosomal cistron was performed. Sequencer version was utilized to edit and align the DNA sequences, and then sequences were identified using BLAST. The correlation between phenotypic and molecular identification was evaluated.

Results:
Gene sequencing identified 50% of clinical isolates as one of the Aspergillus species, followed by Mucorales 29%, Fusarium species 17%, and Cladosporium spp. 4%. Overall, 50% of clinical isolates were identified correctly till the species level by conventional methods. Phenotypic correlation with genotype till genus was 42%, while two isolates were wrongly identified phenotypically. Excellent agreement (100%) till species level between phenotypic and molecular identification for Aspergillus, while Mucorales had an agreement of 71%.

Conclusion:
Traditional phenotypic identification methods for filamentous molds had a good correlation with sequencing up to genus level identification; however, were not reliable up to species level.
Gastritis in Northeast India and North India: A Regional Comparison of Prevalence and Associated Risk Factors
Authors: Mathur Akshita , Gehlot Valentina , Mahant Shweta , Dutta Sangitanjan , Mukhopadhyay Asish Kumar , Das Kunal , Das Rajashree 
Published: March 2024

Background:
Gastritis is one of the most prevalent disorders affecting individuals. Helicobacter
pylori infection, along with other factors such as lifestyle, gender, alcohol drinking, and smoking are causes of gastritis. Northeast Indian population is geographically, ethnically, culturally, and linguistically a blend of its surrounding nations, being different from the North Indian population. The objective of the study was to predict the prevalence and risk factors of gastritis in Northeast India and compare it with North India.

Methods:
A total of 909 dyspeptic patients (Northeast India: 362 and North India: 547) were enrolled and had undergone endoscopy. H.
pylori status was identified, determined, and genotyped. They were divided into gastritis and nongastritis samples based on the presence or absence of gastric ulcerations and erosion. The risk factors for gastritis in Northeast and North India were estimated with Chi-square analysis, odds ratios, and 95% confidence intervals using multiple logistic regression analysis.

Results:
The prevalence of gastritis and H.
pylori infection was higher in Northeast India than North India. The risk factors significantly associated with gastritis in Northeast region were H.
pylori infection, increased smoking, and alcohol drinking and in North region were smoking and body mass index.

Conclusion:
Although our study found the risk factors associated with gastritis in Northeast India, the available data do not provide sufficient evidence. Further studies are recommended.
Quantification of Glycosaminoglycans Using Harmine Extract from Peganum harmala L. in Mucopolysaccharidoses Researches
Authors: El Fissi Houda , Bouzid Fadoua , Achqra Ikram , Sebbar Mohammed Said , Msanda Fouad , Serghini Mohamed Amine , Alif Najat 
Published: March 2024

Background:
Harmine is used in the quantification of glycosaminoglycans (GAGs) for the research on mucopolysaccharidoses (MPSs). Although this product is commercially available, researchers may consider preparing it under laboratory conditions when it is unavailable for various reasons. This research aims to extract harmine from Peganum
harmala L. seeds and determine whether this extract can be used as a substitute for pure harmine in the quantification of GAGs and, consequently, in the research on MPS.

Methods:

P.
harmala L. seeds were obtained from the plant and extracted using methanol. The harmine extract was then used in a spectrophotometric assay on controls, including patients known of having MPS and healthy subjects and patients suspected of having different types of MPS.

Results:
One milligram of harmine extract in 1 ml of ethanol is sufficient to produce the chromogen as that obtained by pure harmine. The chromogen exhibits a peak absorbance peak at 510 nm. The concordance between the two forms of harmine reaches 100%, either for abnormal values seen in GAGs from MPS patients or for normal values in those from healthy controls. Suspicion of having MPS was lifted in investigated patients. The harmine extracted from P.
harmala L. seeds allowed for accurate and reproducible quantification of the GAGs.

Conclusion:
This study demonstrates that harmine extract can be used as a reagent for the quantification of GAGs in the research on MPS when pure harmine is unavailable in the same way as pure harmine.