bluuebunny/crossref_metadata_2025_split huggingface dataset:
Anterior cruciate ligament reconstruction using peroneus longus tendon autograft: a systematic review
Authors: Ghonim Samir S , Hemida Mohamed A , Khater Ahmad H 
Published: April 2024

Abstract

Background
The anterior cruciate ligament is the most commonly injured ligament in the knee; controversy exists about the most suitable graft for anterior cruciate ligament reconstruction (ACLR).

Aim
This study aims to assess the efficiency of peroneus longus tendon (PLT) autograft as a good alternative graft choice for ACLR and to outline the advantages and disadvantages of its use.

Methodology
We searched the literature through PUBMED, Cochrane library, Medscape, direct science, JBJS, and Google scholar with publication date restricted to 10 years range from 2012 to 2022. English literature of prospective studies only were selected with strict inclusion criteria where human studies undergoing arthroscopic ACLR using PLT autograft, which commenting on clinical±imaging outcomes and repeated studies excluded. Eleven studies were included satisfying the predetermined inclusion criteria with a total of 564 patients. Four literatures compared ACLR using PLT autograft versus Hamstring tendon (HT), one literature versus semitendinosus graft, and another versus patellar tendon. After pooling collected data from the desired search studies, the relative risk of each of the intended outcome measures of interest was calculated and tabulated according to IKDC and AOFAS scores.

Results
In four literatures, in total, outcomes of 108 PLT versus 129 HT autografts were analyzed with mean follow-up 10.5 months, reported little difference was found between the two grafts in favor of PLT autograft, with mean score 95.58 for PLT versus 91.65 for HT. Outcomes of 15 PLT versus 15 semitendinosus autografts were analyzed. PLT autograft gave better clinical and biomechanical outcomes than semitendinosus graft as mean IKDC score was 91.58 for PLT versus 88.37 for semitendinosus graft. Outcomes of 50 PLT versus 50 patellar tendon autografts were analyzed, and reported that PLT autograft has a better IKDC score than patellar tendon autograft (96.8 vs. 95.1) and lower graft rupture rate (6 vs. 10%). In five literatures, in total, the outcomes of 189 patients had ACLR using PLT autograft, were analyzed after mean follow up 12.4 months and revealed that mean IKDC score was increased from 64.7 preoperative to 97.8 postoperative. PLT harvest does not appear to affect foot and ankle function to any clinically significant degree with slightly decreased AOFAS score (96.88 ± 4.95).

Conclusion
PLT autograft consider a very promising and ideal graft option for ACLR with excellent functional and biomechanical outcomes. PLT harvest is easy and causes minimal donor-site morbidity.
Prospective Study of the Incidence of Asymptomatic Deep-vein Thrombosis in Postoperative Patients: A Single-center Study
Authors: Agarwal Vivek , Ramakrishnan Dileep , Majumdar Sumantra Shekher , Dwivedi Surjeet Kumar , Dwivedi Sabita 
Published: April 2024

Abstract

Introduction:
Postoperative DVT remains one of the formidable challenges for the surgeon. It is associated with a significant risk of associated morbidity and mortality. Diagnosis of DVT is usually established by the combination of symptoms and imaging, which is most commonly performed noninvasively by color Doppler. However, in multiple instances, the patient may remain asymptomatic, and hence, the diagnosis may be missed.

Aim and Methodology:
This study was performed at tertiary care to study the incidence of asymptomatic DVT in postoperative patients across various specialties. All postoperative patients were subjected to color Doppler on the 1st, 7th, and 30th postoperative days.

Results:
Out of 300 patients who were part of the study over 1 year, 31 patients developed DVT, of which eight were symptomatic. They all were managed as per any other patient of DVT by anticoagulants, class II stockings, and limb elevation. We had no mortality.

Conclusion:
DVT may develop in postoperative cases. It may be fatal if not recognized and treated in time. Timely diagnosis and adequate management remain key in avoiding morbidity and mortality. Data related to postoperative patients developing asymptomatic DVT are limited. There seems to be ambiguity in its etiology, prognosis, management protocol, and follow-up.
Retained Inferior Vena Cava Filter Retrieval: Novel Approach Using Tiger Tooth Foreign Body Holding Forceps
Authors: Balachandran Saravanan , Omprakash Shanmuganandam , Rajkumar Murugesan , Prakash Junia 
Published: April 2024

Abstract
Only about one-third of all inferior vena cava (IVC) filters are successfully retrieved. This is largely due to factors such as IVC occlusion, filter tilt, and caval wall penetration among other reasons. IVC filter retrieval methods currently followed in practice involve the use of standard snares and wires, endobronchial forceps, LASER-tipped sheaths, and even open surgery. However, the success rate of filter retrieval continues to remain low, thereby increasing the risk of complications associated with retained IVC filters. This warrants a need to explore and adopt newer techniques of IVC filter retrieval. In this case report, we describe the novel use of a tiger tooth foreign body holding forceps in the successful retrieval of a retained IVC filter in an elderly man with intracranial hemorrhage.
Effectiveness and safety of regimen containing bedaquiline and delamanid in patients with drug-resistant tuberculosis
Authors: Putra Oki Nugraha , Yulistiani Yulistiani , Soedarsono Soedarsono , Subay Susi 
Published: April 2024

AbstractBackground:Bedaquiline and delamanid have been included in the individualized treatment regimen (ITR) to treat patients with drug-resistant tuberculosis (DR-TB).Objective:The objective of this study is to compare the effectiveness of sputum culture conversion and the safety of ITR containing bedaquiline and delamanid.Methods:Data were collected retrospectively from medical records of DR-TB patients who received ITR between January 2020 and December 2021. Patients were divided into bedaquiline and bedaquiline-delamanid groups. Sputum culture was evaluated until 6 months of treatment. Measurement of QTc interval, renal and liver function test, and serum potassium were evaluated to assess safety during the study period. We used Chi-square to analyze a difference in cumulative culture conversion; meanwhile, Wilcoxon and Mann–Whitney tests were used to analyze differences in laboratory data for each and between the two groups, respectively.Results:Fifty-one eligible DR-TB patients met the inclusion criteria, 41 in the bedaquiline and 10 in bedaquiline-delamanid group. 43/51 patients had a positive culture at baseline. After 6 months of treatment, 42/43 DR-TB patients (97.6%) had sputum culture conversion and no difference between the two groups (P≥ 0.05). QTc interval within normal limit and no patient had a QTc >500 ms during the study period. Creatinine levels significantly differed between the two groups 6 months after treatment (P< 0.05).Conclusion:DR-TB patients who received all oral ITR containing bedaquiline and or delamanid demonstrated favorable sputum conversion with a tolerable safety profile.
Exploring the association between dermatoglyphic patterns and malocclusion types – A case–control study
Authors: Bhargava Ananya , Bhargava Apoorva , Saluja Imit Pal 
Published: April 2024

ABSTRACT

Background and Objectives:
Dermatoglyphics is the study of fingerprints and skin patterns. During the intrauterine period, the development of dermatoglyphic patterns and dental hard tissues occurs at the same time. Dermatoglyphics has proved to be a potential tool in predicting dental anomalies. Hence, with the help of dermatoglyphics, we can explore the association between various dermatoglyphic patterns and types of malocclusion.

Methods:
A case–control study consisting of 150 children aged 12–14 years was selected. Based on the type of occlusion, the participants were grouped into skeletal class I normal occlusion (controls), skeletal class II malocclusion, and skeletal class III malocclusion. The fingerprints were analyzed using the ink method. The molar relation was determined according to Angle’s classification of malocclusion. The relation of fingerprints was studied with the molar relation recorded using the study models. Dermatoglyphic parameters were examined in these subjects.

Results:
In the study, it was observed that there was a notable increase in the occurrence of whorl pattern among patients with skeletal class II malocclusion (55%) and skeletal class III malocclusion (55.8%). On the other hand, in the skeletal class I group (controls), the frequency of loop pattern (66.6%) was found to be significantly higher. It was also noted that there was a slight decrease in the frequency of whorl patterns in skeletal class II patients as compared to skeletal class III patients.

Conclusion:
The whorl fingerprint pattern found in the study may indicate a higher likelihood of skeletal class II and III malocclusion in the general population.
KEBIJAKAN KURIKULUM MERDEKA DAN IMPLEMENTASINYA DI SEKOLAH DASAR
Authors: Widodo Slamet , Rilianti‬ ‪Adhy Putri , Najwa ‪Wulida Arina , Huda‬ ‪M. Misbachul , Fathoni Anang 
Published: April 2024

The purpose of writing this article is to describe the independent curriculum policy and its implementation on campuses and elementary schools. The type of research used in this study is literature review research. The research approach used is in the form of systematic characteritic samples using sources of written works such as books, articles, policy documents, and other types of written works. The results of the analysis found that the independent learning policy document was 30 articles. This research procedure consists of 4 stages, including: (1) making designs, (2) conducting studies, (3) analyzing, and (4) compiling and writing results. The results of the review are divided into 3, namely: (1) independent curriculum, (2) implementation of independent curriculum on educational campuses, and (3) implementation of independent curriculum in elementary schools. In the independent curriculum, there are several characteristics, including: changes in class hours and teaching teachers, strengthening the profile of Pancasila students, local content, teaching modules, project-based learning, learning outcomes formed phases hierarchically, independent teaching platforms, and curriculum structure. For educational campuses, with the independent curriculum policy, the campus needs to complete course materials with the needs of an independent curriculum, the campus needs to provide learning rights to students to study outside the study program, the campus needs to adjust changes in the definition of credits, and the campus needs to conduct a scheduled study tracer to measure the quality of performance. Each elementary school is free to determine the curriculum to be applied. Some of the tasks if elementary schools implement an independent curriculum are the application of Natural and Social Sciences, the integration of skills lessons in art lessons, and the application of school assessments
ALTERNATIF PENANGANAN MASALAH PERKARA PIDANA DENGAN PENDEKATAN RESTORATIVE JUSTICE
Authors: Hendrawati Sulkiah 
Published: April 2024

Tujuan dari penegakan hukum adalah untuk memberikan perlindungan terhadap semua warga masyarakat dari semua tindak kejahatan yang mungkin terjadi, dengan demikian Negara mempunyai kewajiban untuk mengadakan pencegahan dan penanggulangan kejahatan tersebut, hal ini tidak terlepas diterapkannya sanksi pidana oleh Negara, diamana sanksi pidana merupakan salah satu bagian dari upaya penegakan hukum sebagai sarana untuk melindungi masyarakat. Proses penyelesian melalui sistem peradilan pidana dengan menerapkan sanksi pidana dirasa tidak memberikan efek jera yang sangat signifikan terhadap para pelaku tindak pidana, meningkatnya angka kejahatan setiap tahunnya merupakan bentuk cermin bahwa penyelesaian melalui sistem peradilan pidana tidak begitu efektif sehingga harus dicarikan alternatif untuk memecahkan permasalahan tersebut, pemecahan masalah yang barang tentu berbeda dengan sistem peradilan pidana yang selama ini kita kenal pada umumnya. Istilah sistem peradilan pidana (criminal justice system) menunjukan mekanisme kerja dalam penanggulangan kejahatan yang menggunakan pendekatan sistem. Pendekatan sistem adalah pendekatan yang melibatkan beberapa unsur di dalamnya sebagai suatu kesatuan yang saling berhubungan (interelasi) dan saling mempengaruhi yang satu dengan yang lain. Melalui pendekatan ini Kepolisian, Kejaksaan, Pengadilan dan Lembaga Pemasyarakatan merupakan unsur penting dalam sistem peradilan pidana.
Laboratoriya darslarida yig‘uvchi va sochuvchi linzalarning fokus masofasini aniqlash metodikasi
Authors: Mamatov Zayniddin , Zoirov Sanjaridin 
Published: April 2024

Ushbu maqolada laboratoriya darslarida yig‘uvchi va sochuvchi linzalarning fokus masofasini aniqlashning bir necha usullari yoritilgan hamda tajribada sochuvchi linzaning fokus masofasini aniqlash bo‘yicha uslubiy ko‘rsatmalar berilgan. Laboratoriya darslarida mos ravishda ilg‘or pedagogik texnologiyalardan foydalanish usullari yoritilgan.
Potensi Ekstrak Daun Ficus deltoidea Jack sebagai Anti Kanker Payudara
Authors: Putri Rizky Clarinta , Kusmardi Kusmardi , Hakim Rani Wardani 
Published: April 2024

Kanker payudara merupakan kanker yang paling banyak didiagnosis di seluruh dunia pada tahun 2020, diikuti oleh kanker paru-paru, kolorektal, prostat, dan perut. Sebanyak 2,3 juta kasus kanker payudara terjadi atau 11,7% dari 18,1 juta total keseluruhan kasus kanker di dunia. Pada tahun 2040, kasus kanker payudara diperkirakan akan meningkat menjadi 3 juta kasus per tahun. Pada tahun 2020, di Indonesia, jumlah kasus kanker payudara mencapai 68.858 kasus (16,6%) dari total 396.914 kasus kanker yang terjadi. Angka kejadian dan kematian akibat kanker payudara masing-masing adalah 44 dan 15,3 per 100.000 penduduk di Indonesia.
NGHIÊN CỨU CHỈ ĐỊNH PHẪU THUẬT CẮT MỘT THÙY TUYẾN GIÁP ĐIỀU TRỊ UNG THƯ TUYẾN GIÁP THỂ BIỆT HÓA NGUY CƠ THẤP TẠI BỆNH VIỆN ĐA KHOA TỈNH THÁI BÌNH
Authors: Nguyễn Minh An , Phan Hoài Nam 
Published: April 2024

Mục tiêu nghiên cứu: Nghiên cứu chỉ định phẫu thuật cắt một thùy tuyến giáp điều trị ung thư tuyến giáp thể biệt hóa nguy cơ thấp tại bệnh viện đa khoa Tỉnh Thái Bình. Phương pháp nghiên cứu: Nghiên cứu mô tả cắt ngang 30 bệnh nhân ung thư tuyến giáp thể biệt hóa được điều trị tại bệnh viện đa khoa tỉnh Thái Bình. Kết quả nghiên cứu: Tuổi trung bình của bệnh nhân trong nhóm nghiên cứu là 50,7 ± 8,1 tuổi; Tỷ lệ nữ /nam là 5/1; Thời gian phát hiện bệnh trước 6 tháng chiếm 63,3%, từ 6 -12 tháng chiếm 30,0% và > 12 chiếm 6,7%; Thời gian trung bình từ khi phát hiện triệu chứng đầu tiên đến khi được phẫu thuật là 5,3 tháng ± 1,2 tháng; Đặc điểm khối u tuyến giáp trên siêu âm: TIRADS 5 chiếm tỷ lệ cao nhất là 66,7%, Kích thước u tuyến giáp trung bình trên siêu âm là 0,67 ± 0,22 cm, vị trí u thùy phải chiếm 56,7% u thùy trái chiếm 43,3%; 100% số bệnh nhân được chọc hút tế bào bằng kim nhỏ trước phẫu thuật; Kết quả giải phẫu bệnh ung thư tuyến giáp thể nhú chiếm tỷ lệ 90%, ung thư tuyến giáp thể nang chiếm 10%. Kết luận: Kết quả nghiên cứu chỉ định phẫu thuật cắt một thùy tuyến giáp điều trị ung thư tuyến giáp thể biệt hóa nguy cơ thấp tại bệnh viện đa khoa tỉnh thái bình cho thấy: Kích thước u tuyến giáp trung bình trên siêu âm là 0,67 ± 0,22 cm, vị trí u thùy phải chiếm 56,7% u thùy trái chiếm 43,3%; Ung thư tuyến giáp thể nhú chiếm tỷ lệ 90%, ung thư tuyến giáp thể nang chiếm 10%.
ĐÁNH GIÁ HIỆU QUẢ GIẢM ĐAU SAU MỔ LẤY THAI CỦA PARACETAMOL SO VỚI DICLOFENAC TẠI BỆNH VIỆN NHÂN DÂN GIA ĐỊNH
Authors: Bùi Chí Thương , Nguyễn Thị Hồng Nhung 
Published: April 2024

Đặt vấn đề: Tỷ lệ mổ lấy thai tăng nhanh trong vòng 20 năm trở lại đây. Một trong những vấn đề gây lo ngại nhiều nhất sau mổ lấy thai là tình trạng đau. Trong một số thử nghiệm lâm sàng, việc áp dụng các biện pháp giảm đau khác nhau cho hiệu quả giảm đau thay đổi. Vấn đề thường đặt ra cho các bác sĩ sản khoa là hiệu quả giảm đau của dạng thuốc đặt có tương đương với dạng tiêm truyền hay không, nhất là vào ngày đầu tiên sau phẫu thuật. Mục tiêu: So sánh hiệu quả giảm đau sau mổ lấy thai của Paracetamol so với Diclofenac dựa trên mức độ đau trong ngày đầu tiên sau mổ lấy thai. Phương pháp: Nghiên cứu đoàn hệ tiến cứu, tiến hành trên 41 sản phụ sử dụng Diclofenac, và 49 sản phụ sử dụng Paracetamol từ 04/2023 đến 06/2023 tại bệnh viện Nhân dân Gia Định. Kết quả: Hiệu quả giảm đau của Diclofenac và Paracetamol trên nhóm sản phụ ngày đầu tiên sau mổ lấy thai với VAS lần lượt là 3,6 ± 1,4 và 6,6 ± 1,2, p < 0,001. So sánh tiền căn mổ lấy thai với VAS là 4,92±2,15 ở nhóm có vết mổ cũ và 5,57± 1,73 P=0,016 ở nhóm chưa từng mổ lấy thai. Ở nhóm đau nhẹ - vừa và nhóm đau nặng, có 2 yếu tố liên quan là cân nặng trẻ lúc sanh là 3182,7 ± 361 g, và 3466,7 ± 655,7 g, P=0,002, và lượng máu mất là 339,5 ± 70,1 ml và 466,7 ± 200 ml P<0,001. Kết luận: Diclofenac hiệu quả giảm đau tốt hơn Paracetamol trong ngày đầu tiên sau mổ lấy thai. Có 3 yếu tố liên quan đến mức độ đau sau mổ lấy thai là cân nặng trẻ lúc sanh, lượng máu mất và tiền căn mổ lấy thai. Không ghi nhận tác dụng không mong muốn của thuốc
Drospirenone (Slynd)
Authors: CADTH  
Published: April 2024

CADTH recommends that Slynd should be reimbursed by public drug plans for conception control in adolescent and adult women if certain conditions are met.
Slynd should be covered for conception control in adolescent and adult women provided that Slynd is listed in a similar way to other oral contraceptive pills currently reimbursed by public drug plans for the prevention of pregnancy.
Slynd should only be reimbursed if the cost does not exceed that of other progestin-only pills (POPs) for contraception.
Efgartigimod Alfa (Vyvgart)
Authors: CADTH  
Published: April 2024

CADTH reimbursement reviews are comprehensive assessments of the clinical effectiveness and cost-effectiveness, as well as patient and clinician perspectives, of a drug or drug class.
The assessments inform non-binding recommendations that help guide the reimbursement decisions of Canada’s federal, provincial, and territorial governments, with the exception of Quebec.
This review assesses efgartigimod alfa (Vyvgart), 20 mg/mL solution, 10 mg/kg administered as an IV infusion over 1 hour once weekly for 4 doses (i.e., weeks 0 to 3). For patients weighing 120 kg or more, the recommended dose of efgartigimod alfa is 1,200 mg (3 vials) per infusion.
Indication: For the treatment of adult patients with generalized myasthenia gravis (gMG) who are anti-acetylcholine receptor (AChR) antibody positive.
Новые данные по совкообразным (Lepidoptera, Erebidae, Nolidae, Noctuidae) Белгородской области
Authors: Годин Александр Егорович , Матов Алексей Юрьевич 
Published: April 2024

Впервые для Белгородской области приводятся 13 видов Noctuoidea из семейств Erebidae и Noctuidae: Zanclognatha tarsipennalis, Catocala hymenaea, Athetis gluteosa, A. pallustris, Proxenus lepigone, Chloantha hyperici, Cleoceris scoriacea, Ammoconia caecimacula, Leucania obsoleta, Agrotis cinerea, Diarsia brunnea, Noctua fimbriata и N. janthe. Из них 4 вида приведены также впервые для Центрально-Чернозёмного региона России: Catocala hymenaea, Chloantha hyperici, Cleoceris scoriacea и Noctua janthe. Для 7 видов, считающихся или ранее считавшихся редкими (Meganola albula, Acronicta cinerea, Caradrina terrea, Apamea oblonga, Enargia paleacea, Sideridis lampra и Xestia triangulum), мы приводим дополнительный коллекционный материал, а для большинства из них указываем и дополнительные места находок.
Финансирование: работа А.Е. Година выполнена при поддержке темы государственного задания ФГБУ «Государственный заповедник «Белогорье» № 122062100085-3 «Изучение естественного хода процессов и явлений по программе «Летопись природы» в заповеднике «Белогорье»; работа А.Ю. Матова выполнена при поддержке темы государственного задания № 122031100272-3 «Систематика, морфология, экофизиология и эволюция насекомых».
Spivak’s gender based Subaltern Concerns and Gendered Subalternity in Arundhathi Roy’s The Ministry of Utmost Happiness
Authors: Saadia Rizwana , Dhamyal Saima Anwar , Iqbal Shaista 
Published: April 2024

The Ministry of Utmost Happiness, is a superb exemplum of fiction at its best while highlighting the issues of marginality and subalternity. It is a story of human resilience and determination. The incendiary borders in the novel create solidarity as opposed to alienation. Roy declares that she is an optimist. She gives a direction to directionless, a new strength and vigor to the marginalized subalterns, and a voice to the voiceless. The Ministry of Utmost Happiness depicts Arundhati Roy’s attempt to bring all the subalterns and marginalized castaways of India under one roof. The present research has been conducted to fill up the gaps present in the subaltern perspective. Gayatri Chakravorty Spivak’s theory of subalternity is specifically gender based. Roy depicts a typical Indian society, in this saga of subalterns. All the characters are trying to reclaim their identities and they emerge triumphant at the end when they rediscover the true meanings of life, while facing their respective dilemmas of existence.
Domain Engineering Concepts enabled by Topological Defects
Authors: Schultheiß Jan 
Published: April 2024

The functionality of ferroelectric materials is intricately linked to their domain morphology. Recent research has unveiled dislocations and precipitates as effective tools for controlling the domains in ferroelectrics. Furthermore, topological electric structures are attracting attention, giving conceptually new opportunities for domain engineering.Here, we explore the possibility to use topologically protected vortex/anti-vortex structures to tailor the ferroelectric domains in polycrystalline hexagonal manganites. Unlike conventional ferroelectrics, like BaTiO3 and Pb(Zr,Ti)O3, we observe an inverted scaling behavior where larger grains yield smaller domains. This atypical scaling behavior is explained based on the interplay of the topologically protected vortices with elastic strain fields. We further demonstrate the harnessing of this unique interaction to engineer domain structures via external elastic stresses. The synergy of elastic strain and topological defects offers a novel approach for tailoring the electromechanical and dielectric performance of ferroelectrics, enhancing their potential in capacitor applications and domain wall-based nanoelectronics.