bluuebunny/crossref_metadata_2025_split huggingface dataset:
Gold(I) and Silver(I) Complexes Containing Hybrid Sulfonamide/Thiourea Ligands as Potential Leishmanicidal Agents
Authors: Borges Alice P. , Obata Malu M. S. , Libardi Silvia H. , Trevisan Rafael O. , Deflon Victor M. , Abram Ulrich , Ferreira Francis B. , Costa Luiz Antônio S. , Patrocínio Antonio O. T. , da Silva Marcos V. , Borges Júlio C. , Maia Pedro I. S. 
Published: March 2024

Leishmaniasis is a group of parasitic diseases with the potential to infect more than 1 billion people; however, its treatment is still old and inadequate. In order to contribute to changing this view, this work consisted of the development of complexes derived from MI metal ions with thioureas, aiming to obtain potential leishmanicidal agents. The thiourea ligands (HLR) were obtained by reactions of p-toluenesulfohydrazide with R-isothiocyanates and were used in complexation reactions with AgI and AuI, leading to the formation of complexes of composition [M(HLR)2]X (M = Ag or Au; X = NO3− or Cl−). All compounds were characterized by FTIR, 1H NMR, UV-vis, emission spectroscopy and elemental analysis. Some representatives were additionally studied by ESI-MS and single-crystal XRD. Their properties were further analyzed by DFT calculations. Their cytotoxicity on Vero cells and the extracellular leishmanicidal activity on Leishmania infantum and Leishmania braziliensis cells were evaluated. Additionally, the interaction of the complexes with the Old Yellow enzyme of the L. braziliensis (LbOYE) was examined. The biological tests showed that some compounds present remarkable leishmanicidal activity, even higher than that of the standard drug Glucantime, with different selectivity for the two species of Leishmania. Finally, the interaction studies with LbOYE revealed that this enzyme could be one of their biological targets.
A Study on the Dust Retention Effect of the Vegetation Community in Typical Urban Road Green Spaces—In the Case of Ying Tian Street in Nanjing City
Authors: Sheng Qianqian , Guo Yuanhao , Lu Jiani , Song Shuang , Li Weizheng , Yang Ruizhen , Zhu Zunling 
Published: March 2024

This study aimed to investigate the association between the plant community structure, leaf surface microstructure, nutrient element content, and the dust-retention capacity of garden plants in urban road green spaces. The plant community located along Ying Tian Street in Nanjing City was selected as the focal point of the investigation. Random sampling was performed on the urban road green spaces, determining the amount of dust trapped in plant leaves. Subsequently, the microstructure of the leaf surface was observed, and the content of nutrient elements in the plant leaves was determined. The study also entailed an analysis of the interrelationships between the leaf surface microstructure, plant nutrient element content, and the dust-retention ability of the plants. The findings of this study revealed notable variations in the dust-retention capacity of garden plants and the community structure observed along Ying Tian Street. Among the tree species, Cedrus deodara and Ginkgo biloba exhibited a remarkable dust-retention ability per unit leaf area. Among the shrub species, Abelia × grandiflora and Loropetalum chinense displayed a strong dust-retention capacity per unit leaf area. Similarly, Ophiopogon japonicus and Cynodon dactylon exhibited a robust dust-retention ability per unit leaf area among the herbaceous plants. Furthermore, the dust-retention ability of the plants exhibited a strong positive correlation with the dimensions of leaf stomata, specifically the length and width, while displaying a moderate positive correlation with the width of grooves on the upper and lower surfaces of the leaves. Conversely, the thickness of the leaves did not exhibit a significant correlation. Additionally, the nitrogen content of the leaves exerted a significant influence on the dust-retention ability of the plants (p < 0.05), although the phosphorus and potassium content factors did not exhibit a significant influence (p > 0.05). Based on the findings, it is recommended to prioritize the utilization of plants with robust dust-retention abilities, such as C. deodara, A. grandiflora, O. japonicus, and C. dactylon, and implement a mixed planting approach encompassing a combination of trees, shrubs, and herbaceous plants within urban road green spaces.
Exploration fonctionnelle du territoire des grands lacs alpins par le prisme des services écosystémiques
Authors: Baulaz Yoann , Dorioz Jean-Marcel , Peyrache-Gadeau Véronique 
Published: March 2024

Les services écosystémiques (SE) des grands types d’écosystèmes, comme les forêts, agrosystèmes ou récifs coralliens, ont été
largement décrits, avec la proposition de méthodologies spécifiques, mais peu d’études se sont intéressées à modéliser les différents
services des grands lacs. Les lacs représentent pourtant l’une des principales sources d’eau douce, constituent des lieux de pêche, d’implantation des sociétés, des espaces de loisirs et de bien-être. Dans le cadre de notre étude, l’approche choisie est essentiellement géographique, plaçant au coeur de la modélisation conceptuelle la problématique spatiale et l’analyse des relations entre la qualité de l’eau et les services écosystémiques. Nous avons adapté à l’étude des SE rendus par les grands lacs alpins français (lac d’Annecy, lac du Bourget) et le Léman, l’un des modèles les plus utilisés pour caractériser les services : le modèle de la cascade (Potschin et Haines-Young, 2011). Ce modèle facilite l’identification et la caractérisation des variables-clefs écologiques, socio-économiques et techniques qui modifient le niveau des services rendus par les lacs, tout en mettant en lumière les interactions, rétroactions et chaînes causales associant les lacs à la société. Notre réflexion est une contribution à une nouvelle approche d’étude des territoires limniques, mobilisant le concept de service écosystémique en tant qu’outil de dialogue entre sciences et société. Le concept de SE invite dans l’immédiat à questionner les observatoires actuels de suivi des grands lacs qui sont centrés sur des indicateurs biophysiques (bioindication et flux hydrochimiques) pour qu’ils évoluent dans une approche plus systémique et intégrée, mieux adaptée pour répondre aux enjeux croisés du réchauffement climatique, de l’impact des micropolluants et pour anticiper les évolutions sociétales à venir.
Contribution à la connaissance de la flore du Maroc saharien atlantique
Authors: Chambouleyron Mathieu , Andrieu Frédéric , Charrier Matthieu , Chatelain Cyrille , Léger Jean-François 
Published: March 2024

Ce travail fait la synthèse de plusieurs missions d’inventaires botaniques menées de 2010 à 2019 dans le Sahara atlantique du Maroc. Les découvertes les plus remarquables sont présentées et concernent 93 taxons :
• 32 nouveaux dans au moins une des unités géographiques prospectées, dont un nouveau pour le Maroc et six nouveaux pour le Sahara ;
• 23 endémiques du Maroc ;
• 32 présentant un statut de conservation défavorable au Maroc, selon Fennane (2016-2018) ;
• 16 dont nos observations pourraient marquer la limite méridionale de répartition sur la façade atlantique du Sahara.
Nos données inédites, ici présentées, contribuent à améliorer la connaissance botanique de ce vaste territoire, encore difficile d’accès dans certaines de ses parties et pénalisé par des aléas climatiques le plus souvent défavorables à l’observation de la flore.
HUBUNGAN PANJANG BERAT DAN NISBAH KELAMIN PADA IKAN HIU (Paragaleus tengi) HASIL TANGKAPAN DI PERAIRAN WILAYAH PENGELOLAAN PERIKANAN (WPP) 718, INDONESIA
Authors: Wardani Firdha Iresta 
Published: March 2024

Indonesia merupakan Negara dengan tingkat penangkapan hiu terbesar di dunia, salah satu jenis ikan hiu yang ada di Indonesia adalah Paragaleus tengi. Hiu merupakan hasil tangkapan sampingan dari berbagai alat tangkap seperti jaring ingsang, pancing, pukat hela (trawl), pukat cincin, trammel net dan bubu. Permintaan akan ekspor hiu yang meningkat dapat mengakibatkan tingginya tingkat penangkapan akan hiu. Tujuan penelitian ini adalah memberikan gambaran karateristik ikan hiu (Paragaleus tengi). Karateristik biologi yang dimaksud adalah hubungan panjang berat, distribusi panjang dan nisbah kelamin. Pengambilan data dilakukan bulan Februari sampai bulan Agustus 2022. Sampel Ikan merupakan sampel ikan hiu yang didaratkan di Pelabuhan Perikanan Samudera Nizam Zachman (PPSNZ) Muara Baru-Jakarta Utara dan merupakan hasil tangkapan dari nelayan WPP 718. Hasil penelitian menunjukan ikan hiu yang tertangkap dominan memiliki panjang cagak berkisar 61,8-67,3 cm dengan pola pertumbuhan adalah allometrik negatif dimana pertumbuhan panjang lebih cepat dari pada pertumbuhan berat. Perbandingan jenis kelamin didapatkan ikan betina lebih banyak dari pada jantan tetapi dengan selisih yang tidak jauh, sehingga dari uji chi-square nisbah kelamin ikan Paragaleus tengi masih seimbang.
From english teachers’ perceptions: English learning demotivating factors for Indonesian University students
Authors: Saifullah Saifullah 
Published: March 2024

Students’ demotivation is a crucial issue in EFL context that has not yet received sufficient research particularly in higher education level. In Indonesia English as a foreign language context, students’ demotivation in language learning is mostly addressed based on students’ perceptions. The purpose of the current study is to examine Indonesian university EFL teachers’ perceptions of factors demotivate students to study English at university level in Indonesia. To collect the qualitative data, five teachers from English study program were involved in a semi-structured interviews with additional follow-up questions to further explore the raised concerns. These teachers were asked to understand their perceptions and experiences on what factors demotivate their students to study English. Seven demotivating factors were identified in teachers’ perception that demotivate students to study English: students’ attitudes toward English, students’ past experience, peers proficiency, teachers’ workload, classroom availability, hot and suffocating classroom, and technological facilities. This study has some implications for higher education policy makers, institutional authorities, EFL students, and EFL teachers in particular.
Broadband heterodyne electro-optic sampling using a lithium niobate ridge-waveguide
Authors: Mine S. , Gandubert G. , Nkeck J. E. , Ropagnol X. , Murate K. , Blanchard F. 
Published: March 2024

Abstract
We demonstrated the bandwidth broadening of terahertz waves detected by heterodyne electro-optical sampling by implementing a ridge waveguide structure in a lithium niobate (LiNbO3) crystal. Such an approach effectively reduces absorption loss, eases the phase matching condition and enhances the nonlinear interaction length through the optical confinement effect. As a result, we have more than doubled the bandwidth and improved the signal-to-noise ratio compared with an equivalent approach in a bulk LiNbO3 crystal. Heterodyne electro-optic sampling in a ridged-waveguide structure is only marginally dependent on the probe beam wavelength, suggesting its potential as a versatile method for broadband terahertz detection.
Enhancement of remnant polarization in ferroelectric HfO2 thin films induced by mechanical uniaxial tensile strain after the crystallization process
Authors: Inoue Tatsuya , Onaya Takashi , Kita Koji 
Published: March 2024

Abstract
The effect of strain on the ferroelectricity of HfO2 thin films after crystallization was investigated by applying uniaxial mechanical strains to Au/HfO2/TiN metal–ferroelectric–metal (MFM) capacitors. The remnant polarization (2P
r) of MFM capacitors increased when tensile strain was applied during polarization switching. This phenomenon should not be attributed to phase transformation from the non-ferroelectric to the ferroelectric phase, taking account of the fast relaxation of 2P
r after removal of the mechanical strain and the fact that the crystal structure of HfO2 thin films evaluated by grazing incidence X-ray diffraction measurement was not changed by the tensile strain.
БРЕНДИНГ ЯК ОДИН ІЗ ЕФЕКТИВНИХ ІНСТРУМЕНТІВ ПРОСУВАННЯ ОРГАНІЧНОЇ ПРОДУКЦІЇ
Authors: Шматок Артем , Ніфатова Олена 
Published: March 2024

Сучасне суспільство все більше спрямовує свою увагу на здоровий спосіб життя, зосереджуючись на свідомому виборі харчових продуктів та їх впливі на здоров’я людини. Це в свою чергу призвело до значного збільшення попиту на органічні продукти, які вважаються більш безпечними та корисними для здоров'я. Збільшення попиту вплинуло на зростання світового ринку органічних продуктів, підкреслюючи необхідність розвитку та впровадження екологічно орієнтованих підходів. Згідно зі статистичними даними, глобальний обсяг продажів органічної їжі та напоїв у 2020 році зріс на 15%, до 129 мільярдів доларів США за останні п’ять років в порівнянні із 2015 роком [1].
ПЕРСПЕКТИВИ ТА ПРОБЛЕМИ ВИКОРИСТАННЯ ПРЕПАРАТІВ ГЕННОЇ ІНЖЕНЕРІЇ ПРИ ЛІКУВАННІ КАРДІОЛОГІЧНИХ ХВОРИХ
Authors: Долгорук Максим , Гиль Михайло , Ільченко Ірина 
Published: March 2024

Спадкові хвороби серця є актуальними проблемами сьогодення. Найчастішим видом спадкових кардіоміопатій є гіпертрофічну кардіоміопатію. Розвиток спадкових захворювань кодується на рівні транскрипта і ДНК гена, тому дія препаратів направлена на руйнування транскриптів. Сучасними та новітніми препаратами є антисмислові олігонуклеотиди (АСО), які являють собою модифіковані одноланцюгові молекули ДНК, які мають високу протеїн-зв’язувальну здатність. Найбільших практичних успіхів досягнуто в лікуванні захворювань з використанням генозамісної генної терапії, а саме – використання ААВ векторів.
Pedogenesis of pelitic rocks of the Serra da Saudade Formation - Bambuí Group
Authors: Silva Luiz Aníbal da , Ker João Carlos , Camêlo Danilo de Lima , Fontes Maurício Paulo Ferreira , Corrêa Marcelo Metri , Silva David Lukas de Arruda 
Published: March 2024

ABSTRACT
Serra da Saudade Formation corresponds to the upper part of the stratigraphic column of the Bambuí Group. Few studies have addressed the soil properties and pedogenesis of the pelitic rocks rich in potassium minerals of this formation. This study analyzed siltstone-derived soils, some of which are glauconitic (green siltstone; “verdete”), to understand the role of the main pedogenetic factors and processes in the landscape of the Central-West region of the Minas Gerais State, covered by Cerrado vegetation. Nine soil profiles were described, and their morphological, physical, chemical and mineralogical properties were analyzed. Soils were classified as Neossolos Litólicos (P1, P3, P6, P8 and P9), Cambissolos Háplicos (P2 and P5), Argissolo Vermelho-Amarelo (P4) and Argissolo Acinzentado (P7). The main active pedogenetic processes identified in the study area are melanization, goethization, argiluviation and elutriation. These are essentially controlled by the nature of the parent material and position of the soil in the relief. Soils are typically shallow, dystrophic, highly Al-saturated and contain essentially quartz and micas in the coarse fractions (sand and silt) and illite/glauconite and kaolinite in the clay fraction. In soil environments with siltstone and green siltstone under “dry forests”, the soil water pH was higher and high levels of exchangeable calcium and magnesium, a eutrophic character and high-activity clay were observed. Barium, chromium, lead and zinc contents were high in all studied soils. Green siltstone-derived soils have peculiar physical and chemical properties, divergent from those developed from other glauconitic rocks on the Earth surface. However, greenish tones in horizons are common in all these soils.
Granulated fertilizers are more efficient in reducing potassium leaching losses than combining biosolids with inorganic sources
Authors: Netto-Ferreira Julia Barra , Gabetto Fernanda Palmeira , Araujo Ana Carolina Muniz de , Dias Ricardo de Castro , Maltais-Landry Gabriel , Zonta Everaldo 
Published: March 2024

ABSTRACT

Widespread use of soluble mineral fertilizers derived from non-renewable sources has raised concerns about environmental impacts, energy expenditures, and sustainability. Combining biosolid and mineral sources of phosphorus and potassium to produce organomineral fertilizers (OMF) can be used as an alternative nutrient source while reducing the environmental impact of sewage residues. As this approach simultaneously provides nutrients and incorporates organic matter, we hypothesized the presence of an organic source (biosolid) granulated with mineral sources of potassium (K) and phosphorus (P) would reduce leaching due to the benefits of the organic source and the slower release caused by granulation. Our goal was to evaluate the effect of different OMFs on the leaching losses of nutrients. Two forms of isolated N, P, and K sources (granulated and non-granulated), five OMFs with different NPK proportions (1-2-0, 1-4-0, 1-0-2, 1-2-2, 1-2-4), and a control (unfertilized) were evaluated over ten weeks in a leaching column experiment. Non-granulated potassium sulfate exhibited the highest K leaching and did not differ from OMFs with K in their formulation (granulated PS, 1-0-2, 1-2-2, and 1-4-2). Planned contrasts showed that granulation was particularly effective at reducing K leaching, resulting in a 70 % reduction compared to non-granulated PS. While formulation and granulation showed a trend of potential benefits in reducing N-(NO
3
-
+ NO
2
-
) leaching, the effect was not statistically significant. Interaction between fertilizer treatments and leaching events was marginally significant for NH
4
+
leaching, indicating temporal variations of OMFs in nutrient dynamics may be influenced by mineralization. As granulation modulated how OMFs affected nutrient leaching dynamics, this highlights the importance of the physical characteristics of fertilizers for effective nutrient management.
Prognostic criteria for the outcome of the first psychotic episode
Authors: Kosovskyi Volodymyr 
Published: March 2024

Based on the examination of 177 patients with a first psychotic episode (F20 — 53 individuals; F23 — 96 people and F25 — 28 people) and dividing them according to the criterion of response to therapy into two comparison groups (a group with symptomatic remission and a group with “residual” symptoms), a frequency analysis of their clinical and psychopathological, pathopsychological and neuropsychological characteristics and diagnostic markers of positive and negative prognosis of the outcome of the first psychotic episode were determined. It has been established that a positive prognosis of the outcome is determined, first of all, by clinical and anamnestic and pathopsychological features, while a negative prognosis is indicated by clinical and anamnestic and clinical and psychopathological features.
Key words:	primary psychotic episode, prognosis, outcome, diagnostic markers
Entomofauna edáfica associada ao cultivo de algodão transgênico no cone sul de Rondônia
Authors: Machado Cardoso Lucas Henrique , Fonseca do Nascimento Aline , Martinho Silveira Herica , Oliveira Eduardo , Budach Silva Franco Leidiane 
Published: March 2024

Â O estado de Rondônia estava incluído nas zonas de exclusão para o plantio do algodão geneticamente modificado. Essas áreas foram instituídas em 2005, pela Comissão Técnica Nacional de Biossegurança (CTNBio), com o objetivo de preservar a variabilidade de algodoeiros não cultivados (nativos e naturalizados) de eventuais efeitos adversos decorrentes do fluxo gênico com algodoeiros geneticamente modificados. No entanto, os insetos endêmicos da região, pragas e inimigos naturais, associados ao algodoeiro geneticamente modificado, não foram levantados. Tais informações são fundamentais para a atualização de programas de manejo integrado de pragas. Desse modo, o objetivo do presente estudo foi avaliar a entomofauna associada Ã cultura do algodoeiro geneticamente modificado na região do Cone Sul de Rondônia, tendo como enfoque as áreas plantadas na cidade de Vilhena, auxiliando na elaboração do manejo integrado de pragas na região. Foi possível observar que a maioria dos insetos encontrados nas amostras constituem-se de inimigos naturais de pragas agrícolas ou mesmo recicladores de matéria orgânica. Tesourinhas (Labiduridae), moscas (Muscidae), abelhas (Apidae), besouros (Carabidae), moscas de carne (Sarcophagidae) e formigas (Formicidae) foram os insetos mais representativos encontrados. Observou-se que a maioria dos insetos encontrados são benéficos para o solo e para cultura, sendo importante buscar meios de controles de pragas que sejam seletivos, com o intuito de preservar essa entomofauna encontrada.
Analisis Formalin Dalam Ikan Tongkol Pindang Sebelum Perebusan dan Setelah Perebusan Dalam Berbagai Waktu
Authors: Kristianingsih Yuli , Sugiantari Nining , Rahayu Cahyawati , Nurdiani Catu Umirestu , Ardiansyah Renaldi , Masdianto Masdianto , Sediarso Sediarso 
Published: March 2024

Ikan tongkol pindang merupakan olahan hasil laut yang memiliki kandungan protein tinggi sehingga ikan tongkol pindang mudah membusuk. Formalin digunakan sebagai pengawet untuk memperpanjang masa penyimpanan ikan tongkol pindang. Penggunaan formalin dapat menyebabkan bahaya bagi kesehatan manusia. Formalin dilarang digunakan sebagai pengawet pangan berdasarkan Peraturan Menteri Kesehatan Indonesia Nomor 33 tahun 2012.Tujuan penelitian ini untuk mengindentifikasi dan mengetahui kadar formalin serta melihat perbedaan penurunan kadar formalin sebelum dan sesudah perebusan pada ikan tongkol pindang dengan waktu 5, 10 dan 15 menit. Identifikasi formalin pada ikan tongkol pindang menggunakan pereaksi KMnO4. Penetapan kadar dilakukan dengan menggunakan metode spektrofotometri. Hasil uji kualitatif didapat 6 (100%) sampel ikan tongkol pindang positif mengandung formalin. Rata-rata penurunan kadar formalin setelah perebusan ikan tongkol pindang dengan lama waktu 5 menit 93,02 %, 10 menit 95,63 % dan 15 menit 97,44 %. Hasil uji One way Anova didapatkan p value 0,000 0,05 terjadi penurunan kadar formalin yang signifikan pada ikan tongkol pindang dengan perbedaan lama perebusan. Simpulan semakin lama perebusan maka penurunan kadar formalin ikan tongkol pindang semakin tinggi.Kata kunci : Ikan Tongkol Pindang, Formalin, Spektrofotometri,
Attentional biases to signals of negative information: Reliable measurement across three anxiety domains
Authors: Basanovic Julian 
Published: March 2024

AbstractCognitive models propose that individuals with elevated vulnerability to experiencing negative emotion are characterised by biased attentional responding to negative information. Typically, methods of examining these biases have measured attention to pictures of emotional scenes, emotional faces, or rewarding or feared objects. Though these approaches have repeatedly yielded evidence of anxiety-linked biases, their measurement reliability is suggested to be poor. Recent research has shown that attentional responding to cues signalling negative information can be measured with greater reliability. However, whether such biases are associated with emotion vulnerability remains to be demonstrated. The present study conducted three experiments that recruited participants who varied in trait and state anxiety (N = 134), social anxiety (N = 122), or spider fear (N = 131) to complete an assessment of selective attention to cues signalling emotionally congruent negative information. Analyses demonstrated that anxiety and fear were associated with biased attentional responding to cues signalling negative information, and that such biases could be measured with acceptable reliability (rsplit-half = .69–.81). Implications for research on the relation between emotion and attention are discussed.