bluuebunny/crossref_metadata_2025_split huggingface dataset:
Modulation of therapeutic antibody effector functions by glycosylation engineering: Influence of Golgi enzyme localization domain and co‐expression of heterologous β1, 4‐N‐acetylglucosaminyltransferase III and Golgi α‐mannosidase II
Authors: Ferrara Claudia , Brünker Peter , Suter Tobias , Moser Samuel , Püntener Ursula , Umaña Pablo 
Published: January 2006

AbstractThe effector functions elicited by IgG antibodies strongly depend on the carbohydrate moiety linked to the Fc region of the protein. Therefore several approaches have been developed to rationally manipulate these glycans and improve the biological functions of the antibody. Overexpression of recombinant β1,4‐N‐acetylglucosaminyltransferase III (GnT‐III) in production cell lines leads to antibodies enriched in bisected oligosaccharides. Moreover, GnT‐III overexpression leads to increases in non‐fucosylated and hybrid oligosaccharides. Such antibody glycovariants have increased antibody‐dependent cellular cytotoxicity (ADCC). To explore a further variable besides overexpression of GnT‐III, we exchanged the localization domain of GnT‐III with that of other Golgi‐resident enzymes. Our results indicate that chimeric GnT‐III can compete even more efficiently against the endogenous core α1,6‐fucosyltransferase (α1,6‐FucT) and Golgi α‐mannosidase II (ManII) leading to higher proportions of bisected non‐fucosylated hybrid glycans (“Glyco‐1” antibody). The co‐expression of GnT‐III and ManII led to a similar degree of non‐fucosylation as that obtained for Glyco‐1, but the majority of the oligosaccharides linked to this antibody (“Glyco‐2”) are of the complex type. These glycovariants feature strongly increased ADCC activity compared to the unmodified antibody, while Glyco‐1 (hybrid‐rich) features reduced complement‐dependent cytotoxicity (CDC) compared to Glyco‐2 or unmodified antibody. We show that apart from GnT‐III overexpression, engineering of GnT‐III localization is a versatile tool to modulate the biological activities of antibodies relevant for their therapeutic application. © 2006 Wiley Periodicals, Inc.
Absorptive capacity and interpretation system's impact when ‘going green’: an empirical study of ford, volvo cars and toyota
Authors: Williander Mats 
Published: January 2006

AbstractWhether or not it pays to be green or under what circumstances is an important ongoing debate among economic researchers. However, this question, with its rather instrumental rationality, may underestimate another key issue: the ability of companies to create value that can be captured from customers. This paper reports on three companies in the automotive industry developing and launching cars with improved eco‐environmental performance and less petrol consumption. The study reveals that, despite being captured in the same technological paradigm, the individual company's mode of environmental interpretation and its aspiration to exploit new technology may be two important explanatory factors in its ability to go green profitably. The study indicates that an enacting mode of environmental interpretation may be superior to a discovering mode, and suggests that for companies having a discovering mode there may be a need to complement existing engineering practice with insights into consumer psychology, and bundling of common good versus private good product attributes. The research upon which this paper is based was conducted using an insider/outsider approach in studying the three companies. Copyright © 2006 John Wiley & Sons, Ltd and ERP Environment.
Corporate environmental non‐reporting – a UK FTSE 350 perspective
Authors: Martin A. D. , Hadley D. J. 
Published: January 2006

AbstractUntil relatively recently the majority of large publicly listed UK companies have not produced annual environmental reports. Of particular note is the slow take‐up of environmental reporting amongst the UK's top 350 companies, the FTSE 350. Using the results of a postal questionnaire, the reluctance of a majority of the FTSE 350 to voluntarily report is linked to 13 drawbacks. Results from non‐reporting respondents to the questionnaire allowed the relative importance of these drawbacks to be placed in a ranked order. Senior management doubt over the advantages of reporting was shown to be the most important drawback, closely followed by the effort required for data collection. A comparison in the uptake of corporate environmental management practices (other than reporting) was also made amongst reporters and non‐reporters. Reporters were shown to have a generally higher level of uptake, although company sector type and size was influential on environmental engagement overall. Copyright © 2006 John Wiley & Sons, Ltd and ERP Environment.
Gaseous HgH2, CdH2, and ZnH2.
Authors: Shayesteh Alireza , Yu Shanshan , Bernath Peter F. 
Published: January 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access the actual ChemInform Abstract, please click on HTML or PDF.
Structure and Bonding of Zinc Antimonides: Complex Frameworks and Narrow Band Gaps.
Authors: Mikhaylushkin Arkady S. , Nylen Johanna , Haeussermann Ulrich 
Published: January 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access the actual ChemInform Abstract, please click on HTML or PDF.
Ag5Te2Cl1‐xBrx (x = 0—0.65) and Ag5Te2‐ySyCl (y = 0—0.3): Variation of Physical Properties in Silver(I) Chalcogenide Halides.
Authors: Nilges Tom , Lange Stefan 
Published: January 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access the actual ChemInform Abstract, please click on HTML or PDF.
Thermodynamic Characteristics of the Al‐ and Cu‐Doped NdNiIn Hydrides
Authors: Sato Masashi , Denys R. V. , Riabov A. B. , Vartys V. A. 
Published: January 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access the actual ChemInform Abstract, please click on HTML or PDF.
The Chemical Bond in Polyphosphides: Crystal Structures, the Electron Localization Function, and New View of Aromaticity in P42‐ and P5‐.
Authors: Kraus Florian , Korber Nikolaus 
Published: January 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access the actual ChemInform Abstract, please click on HTML or PDF.
New Skeletal 3D Polymeric Inorganic Cluster [W4S16Cu16Cl16]n with Cu in Mixed‐Valence States: Solid‐State Synthesis, Crystal Structure, and Third‐Order Nonlinear Optical Properties.
Authors: Cai Ya , Wang Yan , Li Yizhi , Wang Xiaoshu , Xin Xinquan , Liu Caiming , Zheng Hegen 
Published: January 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access the actual ChemInform Abstract, please click on HTML or PDF.
Deracemization of Quaternary Stereocenters by Pd‐Catalyzed Enantioconvergent Decarboxylative Allylation of Racemic β‐Ketoesters.
Authors: Mohr Justin T. , Behenna Douglas C. , Harned Andrew M. , Stoltz Brian M. 
Published: January 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access the actual ChemInform Abstract, please click on HTML or PDF.
Solvent‐Free Synthesis of Cyanohydrin Derivatives Catalyzed by Triethylamine.
Authors: Baeza Alejandro , Najera Carmen , Retamosa Ma. de Gracia , Sansano Jose M. 
Published: January 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access the actual ChemInform Abstract, please click on HTML or PDF.
Chiral 2,4,6‐Trihydroxycyclohexanones as Potent Building Blocks: A Convenient Method for the Preparation of Enantiomerically Pure Acyclic 1,3‐Diols.
Authors: Kirsch Stefan F. , Bach Thorsten 
Published: January 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access the actual ChemInform Abstract, please click on HTML or PDF.
7‐endo Radical Cyclizations Catalyzed by Titanocene(III). Straightforward Synthesis of Terpenoids with Seven‐Membered Carbocycles.
Authors: Justicia Jose , Oller‐Lopez Juan L. , Campana Araceli G. , Oltra J. Enrique , Cuerva Juan M. , Bunuel Elena , Cardenas Diego J. 
Published: January 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access the actual ChemInform Abstract, please click on HTML or PDF.
Triarylborane Ammonia Complexes as Ideal Precursors for Arylzinc Reagents in Asymmetric Catalysis.
Authors: Dahmen Stefan , Lormann Matthias 
Published: January 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access the actual ChemInform Abstract, please click on HTML or PDF.
Synthesis of Diethynyltriptycene‐Linked Dipyridyl Ligands.
Authors: Kodanko Jeremy J. , Morys Anna J. , Lippard Stephen J. 
Published: January 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access the actual ChemInform Abstract, please click on HTML or PDF.
Enantioselective Reduction of Benzofuryl Halomethyl Ketones: Asymmetric Synthesis of (R)‐Bufuralol.
Authors: Zaidlewicz Marek , Tafelska‐Kaczmarek Agnieszka , Prewysz‐Kwinto Andrzej 
Published: January 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access the actual ChemInform Abstract, please click on HTML or PDF.
Synthesis of 5,6‐Diamino‐1,3‐dihydrobenzo[c]thiophene 2,2‐Dioxide.
Authors: Tashbaev G. A. , Tukhtasunov O. 
Published: January 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access the actual ChemInform Abstract, please click on HTML or PDF.
Stereoselective Synthesis of (2S,3S,4R,5S)‐5‐Methylpyrrolidine‐3,4‐diol Derivatives that Are Highly Selective α‐L‐Fucosidase Inhibitors.
Authors: Moreno‐Vargas Antonio J. , Carmona Ana T. , Mora Federico , Vogel Pierre , Robina Inmaculada 
Published: January 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access the actual ChemInform Abstract, please click on HTML or PDF.
Ligand‐Mediated Enantioselective Synthesis of Acyclic Pyrrole Carbinols.
Authors: Dixon Darren J. , Scott Mark S. , Luckhurst Chris A. 
Published: January 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access the actual ChemInform Abstract, please click on HTML or PDF.
Amination/Annulation of Chlorobutenones with Chiral Amine Compounds: Synthesis of 1,2,4‐Trisubstituted Pyrroles.
Authors: Demir Ayhan S. , Igdir A. Cigdem , Guenay N. Batuhan 
Published: January 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access the actual ChemInform Abstract, please click on HTML or PDF.
Photochromic Dihetarylethylenes. Part 21. Synthesis and Photochemical Properties of 1,2‐Bis{5‐(2‐benzothiazolyl)‐2‐ethylthieno [2,3‐b]thiophen‐3‐yl}hexafluorocyclopentene.
Authors: Krayushkin M. M. , Kalik M. A. , Kozhinov D. V. , Martynkin A. Yu. , Strokach Yu. P. , Barachevsky V. A. 
Published: January 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access the actual ChemInform Abstract, please click on HTML or PDF.
Addition of Ethyl Bromodifluoroacetate to Lactones: Reactivity and Stereoselectivity.
Authors: Cuenca Ana B. , D'Hooge Francois , Gouge Vanessa , Castelot‐Deliencourt Geraldine , Oulyadi Hassan , Leclerc Eric , Jubault Philippe , Pannecoucke Xavier , Quirion Jean‐Charles 
Published: January 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access the actual ChemInform Abstract, please click on HTML or PDF.
Direct Fluorination of Coumarin, 6‐Methyl‐coumarin and 7‐Alkoxy‐coumarins.
Authors: Holling Darren , Sandford Graham , Batsanov Andrei S. , Yufit Dmitrii S. , Howard Judith A. K. 
Published: January 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access the actual ChemInform Abstract, please click on HTML or PDF.
Fused Polycyclic Nitrogen‐Containing Heterocycles. Part 14. Intramolecular Cyclization of 4‐Azidocarbonyl‐2,5‐diphenylthiazole. New Route to Isoquinoline Derivatives.
Authors: Mamedov V. A. , Nurkhametova I. Z. , Gubaidullin A. T. , Rizvanov I. Kh. , Litvinov I. A. , Levin Ya. A. 
Published: January 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access the actual ChemInform Abstract, please click on HTML or PDF.
Synthesis of Pyrido[2,3‐d]pyrimidin‐7(8H)‐one Derivatives from 5‐Acetyl‐4‐aminopyrimidines (I) and β‐Dicarbonyl Compounds.
Authors: Komkov A. V. , Yakovlev I. P. , Dorokhov V. A. 
Published: January 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access the actual ChemInform Abstract, please click on HTML or PDF.
Orally Bioavailable Highly Potent HIV Protease Inhibitors Against PI‐Resistant Virus.
Authors: Lu Zhijian , et al. et al. 
Published: January 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access the actual ChemInform Abstract, please click on HTML or PDF.
Benzamidines in Cyclocondensation with Hexafluoroacetone and Methyl Trifluoropyruvate Acyl‐ and Ethoxycarbonylimines.
Authors: Sokolov V. B. , Aksinenko A. Yu. , Epishina T. A. , Goreva T. V. , Martynov I. V. 
Published: January 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access the actual ChemInform Abstract, please click on HTML or PDF.
A Facile Stereoselective Synthesis of (Z,E)‐2‐Silyl‐Substituted 1,3‐Dienes via Palladium‐Catalyzed Cross‐Coupling Reaction.
Authors: Cai Ming‐Zhong , Ye Xing‐Lin , Wang Ping‐Ping 
Published: January 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access the actual ChemInform Abstract, please click on HTML or PDF.
Synthesis and Inhibitory Effect of Novel Glycyrrhetinic Acid Derivatives on IL‐1β‐Induced Prostaglandin E2 Production in Normal Human Dermal Fibroblasts.
Authors: Tsukahara Michiko , Nishino Takeshi , Furuhashi Ikue , Inoue Hideo , Sato Toshitsugu , Matsumoto Hiroatsu 
Published: January 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access the actual ChemInform Abstract, please click on HTML or PDF.
Two New Saponins from Zygophyllum atriplicoides.
Authors: Ahmad Viqar Uddin , Iqbal Shazia , Kousar Farzana , Bader Sadia , Arshad Saima , Tareen Rasool Bakhsh 
Published: January 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access the actual ChemInform Abstract, please click on HTML or PDF.
New Bisabolane‐Type Sesquiterpenes from the Aerial Parts of Lippia dulcis.
Authors: Ono Masateru , Morinaga Hiroaki , Masuoka Chikako , Ikeda Tsuyoshi , Okawa Masafumi , Kinjo Junei , Nohara Toshihiro 
Published: January 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access the actual ChemInform Abstract, please click on HTML or PDF.
The First Total Synthesis of Acutifolone A, a Pinguisane‐Type Sesquiterpenoid Isolated from the Japanese Liverwort Porella acutifolia subsp. tosana.
Authors: Shiina Junichi , Nishiyama Shigeru 
Published: January 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access the actual ChemInform Abstract, please click on HTML or PDF.
On the Formation of 4‐[N,N‐Bis(2‐chloroethyl)amino]phenyl Acetic Acid Esters of Hecogenin and Aza‐Homo‐Hecogenin and Their Antileukemic Activity.
Authors: Camoutsis Charalambos , Trafalis Dimitrios , Pairas George , Papageorgiou Athanasios 
Published: January 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access the actual ChemInform Abstract, please click on HTML or PDF.
Syntheses of α‐Amino Squaric Acids Using an Aminomalonate Equivalent Bearing a Squaryl Group.
Authors: Ishida Toshikazu , Shinada Tetsuro , Ohfune Yasufumi 
Published: January 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access the actual ChemInform Abstract, please click on HTML or PDF.
Pyrrolizidine Alkaloid Containing Plants Used in Mongolian Traditional Medicine: Lappula myosotis Moench.
Authors: Wiedenfeld Helmut , Amarsanaa B. , Altanchimeg D. , Narantuya S. 
Published: January 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access the actual ChemInform Abstract, please click on HTML or PDF.
Regioselective Glycosylation: Synthesis of α‐Indoline Nucleosides.
Authors: Brown Kenneth L. , Chandra Tilak , Zou Shawn , Valente Edward J. 
Published: January 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access the actual ChemInform Abstract, please click on HTML or PDF.
Unusual Olefin Formation by PhSe‐F trans‐Elimination.
Authors: Du Jinfa , Shi Junxing , Chun Byoung‐Kwon , Hobbs Ann , Hollecker Laurent , Watanabe Kyoichi A. 
Published: January 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access the actual ChemInform Abstract, please click on HTML or PDF.
Constituents of Mushrooms. Part 24. Two New Aromatic Compounds from Hericium erinaceum (Bull.: Fr.) Pers.
Authors: Yaoita Yasunori , Danbara Kuniko , Kikuchi Masao 
Published: January 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access the actual ChemInform Abstract, please click on HTML or PDF.
Total Synthesis of (+)‐Apiosporamide: Assignment of Relative and Absolute Configuration.
Authors: Williams David R. , Kammler David C. , Donnell Andrew F. , Goundry William R. F. 
Published: January 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access the actual ChemInform Abstract, please click on HTML or PDF.
Synthesis and SAR/3D‐QSAR Studies on the COX‐2 Inhibitory Activity of 1,5‐Diarylpyrazoles to Validate the Modified Pharmacophore.
Authors: Singh Sunil K. , Saibaba V. , Rao K. Srinivasa , Reddy P. Ganapati , Daga Pankaj R. , Rajjak S. Abdul , Misra Parimal , Rao Y. Koteswar 
Published: January 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access the actual ChemInform Abstract, please click on HTML or PDF.
Structure—Activity Relationship of Trihexyphenidyl Analogues with Respect to the Dopamine Transporter in the Ongoing Search for a Cocaine Inhibitor.
Authors: Dar D. E. , Thiruvazhi M. , Abraham P. , Kitayama S. , Kopajtic T. A. , Gamliel A. , Slusher B. S. , Carroll F. I. , Uhl G. R. 
Published: January 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access the actual ChemInform Abstract, please click on HTML or PDF.
Magnetic and Charge Correlations in La2‐x‐yNdySrxCuO4: Raman Scattering Study
Authors: Gozar A. , Komiya Seiki , Ando Yoichi , Blumberg G. 
Published: January 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access the actual ChemInform Abstract, please click on HTML or PDF.
Recent Developments in Design and Synthesis of Well‐Defined Ruthenium Metathesis Catalysts— A Highly Successful Opening for Intricate Organic Synthesis
Authors: Dragutan Ileana , Dragutan Valerian , Filip Petru 
Published: January 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access the actual ChemInform Abstract, please click on HTML or PDF.
A Concise Account of Recent SN2′ Grignard Coupling Reactions in Organic Synthesis.
Authors: Kar Anirban , Argade Narshinha P. 
Published: January 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access the actual ChemInform Abstract, please click on HTML or PDF.
A Divergent Synthesis of Triyne Natural Products and Glycosylated Analogues Using a Carbenoid Rearrangement.
Authors: Luu Thanh , Shi Wei , Lowary Todd L. , Tykwinski Rik R. 
Published: January 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access the actual ChemInform Abstract, please click on HTML or PDF.
Diels—Alder Reactions of Imino Dienophiles
Authors: Heintzelman Geoffrey R. , Meigh Ivona R. , Mahajan Yogesh R. , Weinreb Steven M. 
Published: January 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access the actual ChemInform Abstract, please click on HTML or PDF.
Synthetic Diversity and Catalytic Mechanism of Peptide Dendrimers
Authors: Delort Estelle , Darbre Tamis , Reymond Jean‐Louis 
Published: January 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access the actual ChemInform Abstract, please click on HTML or PDF.