bluuebunny/crossref_metadata_2025_split huggingface dataset:
Qualitative Study of Anxiety Facing Block Examinations Among Medical Students at Faculty of Medicine, Universitas Ahmad Dahlan
Authors: Damayanti Gita Angun , Qomariyah Nurul , Hidayah Nurul 
Published: April 2024

Background: Medical students face examinations more frequently compared to students from other faculties. Examinations are one of the causes of anxiety commonly experienced by medical students, leading to both physical and psychological responses. Effective coping mechanisms in response to stressors are necessary for medical students as a defense mechanism. Objective: This research aims to explore the causes of exam anxiety, the contributing factors to anxiety and the coping mechanism used by medical students. Methods: The research adopts a qualitative descriptive design, the sample consist of active medical students from Faculty of Medicine, Ahmad Dahlan University who have faced block examinations. Sample selection was done using a test- anxiety inventory, with participants chosen from each academic year and divided into focus group discussion (FGD) sessions. The FGD results were subsequently analyzed using content analysis in the form of research problem categories. Results: The discovered data consists of the main research issues, which are student’s anxiety when facing block exams, the factors causing anxiety, and student’s coping mechanisms. Conclusion: The high anxiety group portrays block exams as a subjective matter and tends to lead to anxiety, students in low anxiety group predominantly utilize problem-focused coping mechanism.
Meninjau Eksistensi Kebijakan Pemerintah Terhadap Kerentanan Cyber child grooming
Authors: Ishmah Nadhilah , Putri Anggi Fransiska , Sicillia Edna , Arimbawa Ni Putu Vania Leonyta Putri , Ramadhana Aditya Yuda 
Published: April 2024

Riset ini merupakan studi kebijakan untuk menelisik peran pemerintah terhadap kerentanan kekerasan seksual di ranah digital. Tingginya penggunaaan internet oleh anak terutama sejak masa pandemi Covid-19 menciptakan sebuah fenomena kejahatan baru bernama cyber child grooming, yakni sebuah fase pendekatan secara emosional dengan seorang anak melalui internet. Kota Semarang yang memeroleh predikat kota tertinggi untuk kekerasan seksual anak di Jawa Tengah menjadi lokus riset ini. Dalam menganalisis kebijakan kasus cyber child grooming di Kota Semarang, digunakan metode kualitatif untuk mendapatkan data secara komprehensif melalui reduksi data, penyajian data, dan verifikasi yang didapat melalui wawancara mendalam semi terstruktur dengan Pemerintah Kota Semarang dan LSM. Riset ini menemukan bahwa Pemerintah Kota Semarang sampai saat ini belum memiliki kebijakan khusus mengenai kekerasan seksual berbasis elektronik. Penanganan kekerasan seksual berbasis elektronik hanya berlandaskan pada UU Pornografi, UU TPKS, dan UU ITE. Hal ini berdampak pada proses penanganan cyber child grooming yang tidak maksimal, sebab kekerasan seksual berbasis elektronik hanya dapat ditangani apabila korban divisum dan konten seksual telah disebarkan. Hal ini menjadi tidak relevan ketika cyber child grooming merupakan proses awal dari kekerasan seksual yang memengaruhi anak secara psikologis. Upaya Pemerintah Kota Semarang melalui sosialisasi dan penyuluhan belum mampu menjangkau substansi masalah karena belum disertai kebijakan yang bisa melindungi anak secara hukum serta memberikan efek jera bagi pelaku.
Cytotoxic and phytochemical screening of Solanum lycopersicum–Daucus carota hydro-ethanolic extract and in silico evaluation of its lycopene content as anticancer agent
Authors: Ademosun Olabisi Theresa , Agwamba Ernest C. , Ahmad Iqrar , Patel Harun , Louis Hitler , Adebayo Abiodun Humphrey , Ajanaku Kolawole Oluseyi 
Published: April 2024

Abstract
This article explores the potential of a specific functional food mix containing lycopene, a pigment found in tomatoes, for its role in cervical cancer prevention and treatment. The article assesses the cytotoxic effects on cervical cancer cells and conducts molecular docking analysis to understand the biological activities and binding interactions of lycopene. The formulations are analysed for their phytochemical profile, and their in vitro antioxidant activities are evaluated using spectrophotometric methods. Cytotoxicity tests on cervical cancer cells demonstrate that the ethanol extract of tomatoes exhibits the highest cytotoxic inhibition (40.28%), while carrots show minimal cytotoxic effects. Moreover, the lycopene extract exhibits dose-dependent cytotoxicity, with the highest concentration (1,000 µg/mL) displaying remarkable inhibition (74.2%). Molecular docking analysis indicates favourable interactions between lycopene and the pro-apoptotic protein BAX 1, suggesting its potential to induce apoptosis in cervical cancer cells, but camptothecin demonstrated stronger interactions. Molecular dynamics simulations confirm the stability of lycopene–protein complexes throughout the 100 ns simulation, supporting their potential as anticancer agents. Overall, the study highlights the cytotoxic effects of tomato–carrot food extracts and lycopene on cervical cancer cells. Molecular docking reveals the potential of lycopene to induce apoptosis through interactions with BAX 1. The stability analysis of lycopene–protein complexes further supports its anticancer properties. These findings enhance our understanding of the molecular mechanisms underlying the anticancer effects of lycopene and provide insights for future research on novel chemopreventive strategies for cervical cancer. However, further in vivo and clinical studies are warranted to validate the efficacy and safety of lycopene-based interventions.
Protective activities of silver nanoparticles containing Panax japonicus on apoptotic, inflammatory, and oxidative alterations in isoproterenol-induced cardiotoxicity
Authors: Xu Xiao , Diao Zhipeng , Zhao Bo , Xu Huajuan , Yan Shuying , Chen Huilin 
Published: April 2024

Abstract

Panax japonicus has long been utilized as an herbal remedy in Chinese traditional medicine for treating various diseases. In this investigation, we present the environmentally friendly silver nanoparticle (AgNP) synthesis by the aqueous extract of P. japonicas to follow its cardioprotective effects. Through various analytical methods, we identified the nanoparticles (NPs). Our XRD findings revealed the formation of Ag@P. japonicus, while FE-SEM imagery indicated a spherical shape, with NPs measuring less than 40 nm. The UV–Vis and FT-IR spectroscopy confirm the green synthesis of Ag@P. japonicus. In the medicinal section, 45 Wistar rats were utilized. These groups consisted of a normal group, a group that was solely treated with isoproterenol for inducing myocardial infarction, and two groups that were pretreated with AgNPs at different doses for 14 days. These pretreated groups were then challenged with isoproterenol. The expression of PI3K/Akt/mTOR and other downstream inflammatory and apoptotic mediators were followed. Additionally, the expression of Keap1, Nrf2, ECG, cardiac markers, and other downstream antioxidant enzymes were assessed. Treatment with AgNPs ameliorated the apoptosis, inflammation, and myocardial autophagy, regulated the PI3K/Akt/mTOR pathway, increased the antioxidant enzyme efficacies, and activated the Keap1/Nrf2/HO-1 pathway. The findings suggest that AgNPs may have a cardioprotective efficacy on myocardial infarction by mitigating the Keap1/Nrf2 pathway, GST, GPx, GSH, SOD, IL-1β, IL-6, TNF-α, NF-κB, Bax, Bcl2, caspase-9, caspase-3, and PI3K/Akt/mTOR pathway. Furthermore, the treatment decreased the infarct region size, attenuated the cardiac indicators levels, and mitigated immune cell infiltration and myocardial necrosis.
Experimental investigation of dynamic soil properties for modeling energy-absorbing layers
Authors: Abood Ahmed Salah , Fattah Mohammed Y. , Al-Adili Aqeel 
Published: April 2024

Abstract
Modeling the propagation of waves in geomechanics is an essential part of dynamic analysis. In geotechnics, the study of the interaction between the soil and the foundation is particularly interesting. In order to mimic low-speed operating types (less than 1,500 rpm), this study details the creation of a dependable and efficient approach for designing and fabricating the steel box container. When employed as a boundary, an absorbing layer drastically reduces the amount of wave reflection that occurs inside the limited region. The present effort is split into two halves. The first step is to calculate the damping layer’s damping constants, subgrade response modulus, damping ratio, shear modulus, vibration amplitude, and resonant frequency. The second section focuses on the dynamic study of the circular foundation by measuring the vibration amplitude, acceleration, velocity, and displacement caused by harmonic vibration machines. The findings demonstrate that simple material borders prevent the wave from dissipating as a consequence of reflection. Attenuation of waves is possible when the absorbing layer of energy represents semi-infinite soil. When absorbing just one layer, the vertical displacements at positions located at the box side boundary and its base decreased by 65, 63, and 67%, respectively. However, it dropped by 97, 96, and 98%, respectively, when two absorbent layers were used. On the basis of these promising results, the model results were compared with and without the absorbing layer. It would appear that the modeling of the absorbing layer, which is designed as two layers, has been satisfied for low speeds of harmonic vibration.
On projections of the tails of a power
Authors: Corson Samuel M. , Shelah Saharon 
Published: April 2024

Abstract
Let 𝜅 be an inaccessible cardinal, 𝔘 a universal algebra, and

∼

\sim

the equivalence relation on

U
κ

\mathfrak{U}^{\kappa}

of eventual equality.
From mild assumptions on 𝜅, we give general constructions of

E
∈
End

(

U
κ

/
∼
)

\mathcal{E}\in\operatorname{End}(\mathfrak{U}^{\kappa}/{\sim})

satisfying

E
∘
E

=
E

\mathcal{E}\circ\mathcal{E}=\mathcal{E}

which do not descend from

Δ
∈

End
⁡

(

U
κ

)

\Delta\in\operatorname{End}(\mathfrak{U}^{\kappa})

having small strong supports.
As an application, there exists an

E
∈
End

(

Z
κ

/
∼
)

\mathcal{E}\in\operatorname{End}(\mathbb{Z}^{\kappa}/{\sim})

which does not come from a

Δ
∈

End
⁡

(

Z
κ

)

\Delta\in\operatorname{End}(\mathbb{Z}^{\kappa})

.
Effect of heat treatment on the microstructure and mechanical properties of biocompatible Ti–Ta–Nb–Zr alloys prepared by selective laser melting
Authors: Zhang Kai , Zhong Ning , Zhang Xianjin , Wen Chen , Zhou Yun , Lu Shangwen 
Published: April 2024

Abstract
In this paper, a low elastic modulus, non-cytotoxic Ti-10Ta-2Nb-2Zr titanium alloy was prepared by selective laser melting additive manufacturing. The effect of annealing and solution heat treatment on the structure, mechanical properties, and tribological behavior were investigated. The results show that the microstructure was composed of the main α′ phase and a small amount of β phase. Heat treatment improved strength and elongation. The ultimate tensile strength (UTS) and elongation of the deposited specimen were 807 ± 8.74 MPa and 6.6 ± 0.75 %, respectively. After annealing, the UTS was nearly the same, but the elongation increased to 15.3 ± 0.95 %. After solution and aging, the UTS and elongation increased to 873 ∼ 813 MPa and 9.25–11.9 %, respectively. The elastic modulus of the deposited specimen was 120 ± 6.81 GPa. The elastic moduli of heat treated specimens ranged from 74 ± 4.04 to 96 ± 5.13 GPa. The elastic moduli of heat treated specimens were close to that of β-type titanium alloys. The wear mechanism was mainly abrasive wear and oxidative wear. Compared with the deposited and annealed specimens, the solution and age treated specimens had low friction coefficients and much better wear resistance. In terms of properties and cost, the designed alloy has great potential in the medical implant field.
Some transforms, Riemann–Liouville fractional operators, and applications of newly extended M–L (p, s, k) function
Authors: Ayub Umbreen , Mubeen Shahid , Abbas Amir , Khan Aziz , Abdeljawad Thabet 
Published: April 2024

Abstract
There are several problems in physics, such as kinetic energy equation, wave equation, anomalous diffusion process, and viscoelasticity that are described well in the fractional differential equation form. Therefore, the solutions with elementary solution method cannot be solved and described deliberately with detailed physics of the problems, so these problems are solved with the help of special operators such as Mittag–Leffler (M–L) functions equipped with Riemann–Liouville (R–L) fractional operators. Hence, keeping in view the above-mentioned problems in physics in the current study, the generalized properties are derived M–L functions connected with R–L fractional operators that are investigated in the generalized form. These extended special operators will be used for the solutions of generalized kinetic energy equation. The M–L function is a fundamental special function with a wide range of applications in mathematics, physics, engineering, and various scientific disciplines. Ayub et al. gave the definition of newly extended M–L

(

p
,
s
,
k

)

\left(p,s,k)

function. Also, they gave its convergence condition and found several results relevant to that. The purpose of this study is to investigate newly extended M–L function and study its elementary properties and integral transforms such as Whittaker transform and fractional Fourier transform. The R–L fractional operator is a fundamental concept in fractional calculus, a branch of mathematics that generalizes differentiation and integration to non-integer orders. In this study, we discuss the relation of M–L

(

p
,
s
,
k

)

\left(p,s,k)

-function and R–L fractional operators. In some cases, fractional calculus is used to describe kinetic energy equations, particularly in systems where fractional derivatives are more appropriate than classical integer-order derivatives. The M–L function can appear as a solution or as a part of the solution to these fractional kinetic energy equations. Also, we gave the generalization of kinetic energy equation and its solution in terms of newly extended M–L function.
Magnetohydrodynamic water-based hybrid nanofluid flow comprising diamond and copper nanoparticles on a stretching sheet with slips constraints
Authors: Yasmin Humaira , AL-Essa Laila A. , Lone Showkat Ahmad , Alrabaiah Hussam , Raizah Zehba , Saeed Anwar 
Published: April 2024

Abstract
Hybrid nanofluid problems are used for augmentation of thermal transportation in various industrial applications. Therefore, the present problem is studied for the heat and mass transportation features of hybrid nanofluid caused by extending surface along with porous media. In this investigation, the authors have emphasized to analyze hybrid nanofluid flow containing diamond and copper nanoparticles on an extending surface. Furthermore, the velocity, temperature, and concentration slip constraints are adopted to examine the flow of fluid. Heat source, chemical reactivity, thermal radiation, Brownian motion and effects are taken into consideration. Nonlinear modeled equations are converted into dimensionless through similarity variables. By adopting the homotopy analysis method, the resulting equations are simulated analytically. The impacts of various emerging factors on the flow profiles (i.e., velocities, temperature, concentration, skin frictions, local Nusselt number, and Sherwood number) are shown using Figures and Tables. The major key findings reveal that the hybrid nanofluid temperature is higher but the concentration is lower for a Brownian diffusivity parameter. Moreover, increment role of heat transport is achieved due to the increment in radiation factor, thermophoresis, Brownian motion factors, and Eckert number. It has also been observed that velocity in x-direction converges in the region

−
0.8
≤

ℏ

f

≤
0.5

-0.8\le {\hslash }_{\text{f}}\le 0.5

, in y-direction velocity is convergent in the zone

−
0.6
≤

ℏ

g

≤
0.35

-0.6\le {\hslash }_{\text{g}}\le 0.35

, while temperature converges in the region

−
0.6
≤

ℏ

θ

≤
0.4

-0.6\le {\hslash }_{\text{&#x03B8;}}\le 0.4

and concentration converges in the region

−
0.5
≤

ℏ

φ

≤
0.4

-0.5\le {\hslash }_{\text{&#x03C6;}}\le 0.4

.
Pediatric Physical Restraint Coding in US Hospitals: A 2019 Kids Inpatient Database Study
Authors: Luccarelli James , Kalluri Aditya S. , Kalluri Nikita S. , McCoy Thomas H. 
Published: April 2024

BACKGROUND
Reduction of physical restraint utilization is a goal of high-quality hospital care, but there is little nationally-representative data about physical restraint utilization in hospitalized children in the United States. This study reports the rate of physical restraint coding among hospitalizations for patients aged 1 to 18 years old in the United States and explores associated demographic and diagnostic factors.

METHODS
The Kids’ Inpatient Database, an all-payors database of community hospital discharges in the United States, was queried for hospitalizations with a diagnosis of physical restraint status in 2019. Logistic regression using patient sociodemographic characteristics was used to characterize factors associated with physical restraint coding.

RESULTS
A coded diagnosis of physical restraint status was present for 8893 (95% confidence interval [CI]: 8227–9560) hospitalizations among individuals aged 1 to 18 years old, or 0.63% of hospitalizations. Diagnoses associated with physical restraint varied by age, with mental health diagnoses overall the most frequent in an adjusted model, male sex (adjusted odds ratio [aOR] 1.56; 95% CI: 1.47–1.65), Black race (aOR 1.43; 95% CI: 1.33–1.55), a primary mental health or substance diagnosis (aOR 7.13; 95% CI: 6.42–7.90), Medicare or Medicaid insurance (aOR 1.33; 95% CI: 1.24–1.43), and more severe illness (aOR 2.83; 95% CI: 2.73–2.94) were associated with higher odds of a hospitalization involving a physical restraint code.

CONCLUSIONS
Physical restraint coding varied by age, sex, race, region, and disease severity. These results highlight potential disparities in physical restraint utilization, which may have consequences for equity.
A Candid Examination of Mrs Mary Cole
Authors: Boermans Mary-Anne 
Published: April 2024

The author gives an account of the the first British cookbook to openly acknowledge the sources from which its recipes were drawn, Mrs Mary Cole's The Lady’s Complete Guide; or Cookery in All Its Branches, published in 1788. The fact emerges that Mrs Cole's own book included scores of plagarized recipes and there are reasons to ask, did Mrs Mary Cole actually exist?
EMERGÊNCIAS DA PERSPECTIVA INTERDISCIPLINAR EM CURSOS DE LICENCIATURAS EM CIÊNCIAS DA NATUREZA
Authors: Lopes Jéssica Blank , Araujo Rafaele Rodrigues de 
Published: April 2024

A pesquisa buscou investigar como os cursos de formação de professores da área de Ciências da Natureza apresentam a perspectiva interdisciplinar, através dos Projetos Pedagógicos de Cursos (PPCs). Para tal, foi realizada uma análise documental em 29 PPCs de diversas regiões do Brasil. Com as análises realizadas, emergiram dois tópicos de debate: os documentos que apresentam uma discussão sobre a perspectiva interdisciplinar e os documentos que não a definiam. A partir das discussões realizadas, argumentamos que o currículo posto apresenta ainda a fragmentação da organização curricular por meio das disciplinas, de forma que, apesar de emergirem cursos que prezam pela interdisciplinaridade na teoria, não explicitam estratégias que possibilitem a mesma na prática. Dessa forma, nos PPCs que apresentam a perspectiva interdisciplinar, seguem trabalhando suas disciplinas de forma segmentada. Sendo assim, mesmo que proponham uma ação interdisciplinar, a organização de seus PPCs não deixa claro uma possibilidade do trabalho interdisciplinar na formação dos futuros docentes.
SOSIALISASI SERTA PEMBINAAN KULINER DAN NON KULINER KEPADA MASYARAKAT DI KELURAHAN TUNJUNGSEKAR
Authors: Rifandhana Raditya Feda , Pradana Richo Surya , Susianto Susianto , Dwiningrum Wiki , Laksono Agung Budi , Prasetyo Ivan 
Published: April 2024

SOSIALIZATION AND MENTORSHIP IN THE ASPECTS OF CULINARY AND NON-CULINARY FOR COMMUNITY ON TANJUNGSEKAR, INDONESIANThis community service aims to provide knowledge about business permits and online marketing to culinary and non-culinary business actors. The service method involves communicating with the community and sub-district heads in Tunjungsekar Village. This approach is integrated as a learning and practice method, which includes online marketing theory and business license theory, as well as direct practice of online marketing via social media and business license registration via OSS Online. The results of this service include increasing the knowledge and experience of business actors, socializing online marketing, and registering business permits in 2022. The results of this service are expected to increase income for culinary and non-culinary business actors (laundry services).Pengabdian masyarakat ini bertujuan untuk menyediakan pengetahuan tentang ijin usaha dan pemasaran online kepada pelaku usaha kuliner dan non-kuliner. Metode pengabdian melibatkan pendekatan komunikasi kepada masyarakat dan kepala kelurahan di Kelurahan Tunjungsekar. Pendekatan ini diintegrasikan sebagai metode pembelajaran dan praktek, yang mencakup teori pemasaran online dan teori ijin usaha, serta praktek langsung pemasaran online melalui media sosial dan pendaftaran ijin usaha melalui OSS Online. Hasil dari pengabdian ini meliputi peningkatan pengetahuan dan pengalaman pelaku usaha, sosialisasi pemasaran online, pendaftaran ijin usaha Tahun 2022. Hasil pengabdian ini diharapkan dapat meningkatkan pendapatan bagi pelaku usaha kuliner dan non-kuliner (jasa laundry).
Relación clínica entre ictericia no inmune e infección urinaria en recién nacidos
Authors: García Flórez Carolina Andrea , Sánchez Consuegra Ricardo León , Giraldo García Rut Nohemi , García López María Camila , Daza Martínez Sara Marcela 
Published: April 2024

Introducción: el estudio se enfoca en analizar la relación entre la ictericia no inmune y la infección de vía urinaria (IVU) en recién nacidos a término. También se investiga la frecuencia de esta asociación en pacientes con ictericia pero sin fiebre, que muestran evidencia de infección urinaria. Se busca determinar si la infección urinaria desempeña un papel en el desarrollo de ictericia en neonatos, así como explorar otros posibles factores asociados.
Metodología: estudio descriptivo prospectivo de corte transversal, basado en el análisis de historias clínicas de neonatos que desarrollaron ictericia idiopática en los primeros 15 días de vida, entre enero de 2019 y julio de 2021. Se lleva a cabo una descripción paramétrica de las variables recopiladas, así como un análisis detallado de los expedientes de los recién nacidos atendidos en la Clínica General San Diego en Barranquilla, Atlántico.
Resultados: el sexo femenino tuvo un predominio en relación ictericia no inmune e IVU en un 54%, a diferencia del sexo masculino que tuvo un 46%, siendo la edad más frecuente donde se detectaba ictericia no inmune entre los 4 a 8 días de vida y el microorganismo causal de IVU más frecuente, la Escherichia coli (E. coli).
Conclusiones: en recién nacidos con menos de 15 días de vida, diagnosticados con ictericia y que requieren hospitalización para fototerapia basada en las curvas de Bhutani, se debe considerar la posibilidad de una infección de vías urinarias como parte del cuadro clínico o incluso como un factor predictivo. Se sugiere incluir el urocultivo como parte del protocolo de estudio para facilitar el diagnóstico temprano de esta infección del tracto urinario.