bluuebunny/crossref_metadata_2025_split huggingface dataset:
Current management of penetrating injuries of the soft palate
Authors: Randall David A. , Kang D. Richard 
Published: September 2006

Children present to emergency departments with soft palate impalement injuries on an infrequent though periodic basis. Although these usually heal without treatment, internal carotid artery thrombosis occurs on rare occasions due to vessel compression causing intimal disruption. Thirty‐two cases have been reported in the English literature. Hospital observation for up to 72 hours had been recommended previously for all of these injuries because of a, “lucid interval,” usually present before onset of neurologic symptoms. Subsequent studies have shown a very low occurrence of carotid injury and support outpatient observation similar to that after minor head injury. This is further justified by the lack of evidence that any diagnostic study or therapeutic measure alters the ultimate prognosis and outcome. Laceration repair is suggested for retained foreign bodies, through and through injury, or if a large hanging flap is present. Antibiotic indications are not well defined but should be considered for lacerations over 1 to 2 cm in length.
Use of anteriorly based pericranial flap in frontal sinus obliteration
Authors: Moshaver Ali , Harris Jeffery R. , Seikaly Hadi 
Published: September 2006

ObjectiveIn an era of endoscopic sinus surgery, frontal sinus obliteration continues to remain an important treatment option in chronic frontal sinus disease. Numerous avascular obliterative materials including fat, muscle, cancellous bone, and hydroxyapatite have been used in this procedure. In this article, we describe a vascularized anteriorly based pericranial flap to obliterate frontal sinus.Study DesignRetrospective chart review of patients referred to tertiary care hospital between 1996 and 2003.MethodsRecords of the patients who underwent this procedure were reviewed. Demographics, indications, and immediate and late complications were recorded. A phone questionnaire was used to assess patient satisfaction with the outcome.ResultsA total of 12 patients underwent frontal sinus obliteration with this technique. Mean follow‐up was 40 months. None of the patients developed recurrent frontal sinusitis. All of the patients were pleased with the outcome.ConclusionPericranial flap is a highly vascularized flap that is easily harvested and is an effective and viable modality for obliterating frontal sinus.EBM rating: C‐4
Acoustical analysis of snoring: Can the probability of success be predicted?
Authors: Brietzke Scott E. , Mair Eric A. 
Published: September 2006

PurposePalatal flutter snoring is the most common form of snoring. However, other types of snoring do exist. Does identifying palatal snoring beforehand translate into improved subjective treatment success with palatal stiffening procedures?MethodsFifty‐three patients presenting with snoring were evaluated with a commercially available device. The proportion (%) and magnitude of palatal flutter (dB) were quantified. Patients then underwent a palatal stiffening procedure and subjective success/failure was assessed.ResultsOverall subjective treatment success was 85% (45 of 53). The percent palatal flutter was the most predictive of success (area under ROC = 0.8556, 95% CI =. 7428‐.9683). Patients exceeding 68% palatal flutter had a 95% (39 of 41) success rate (P = 0.001, Fisher's exact) and an adjusted odds ratio of treatment success of 25.2 (95% CI = 3.22‐196, P = 0.002).ConclusionPalatal stiffening treatments are successful in the majority of patients. However, identifying patients with predominant palatal flutter snoring significantly increases the probability of subjective treatment success.EBM rating: B‐2b
Local treatment of cricoid cartilage defects with rhBMP‐2 induces growth plate–like morphology of chondrogenesis
Authors: Tcacencu Ion , Carlsöö Bengt , Stierna Pontus , Hultenby Kjell 
Published: September 2006

ObjectiveThe ultrastructural characteristics of new bone and cartilage, induced at the site of cricoid cartilage defects treated with rhBMP‐2 in rabbits, were investigated.Study Design and SettingA cricoid defect model was used. Fifteen rabbits were randomly and equally divided into 3 groups. Four rabbits from each group were treated with rhBMP‐2, while one rabbit from each group was used as control. The rabbits were killed 1, 2, or 4 weeks after surgery. The healing pattern of the laryngeal wound was evaluated by light and transmission electron microscopy.ResultsMineralized collagen type I matrix, osteoblasts, and osteoclast‐like cells were present as early as 1 week after surgery. Well‐structured bone trabeculas and growth plate‐like structures were present 4 weeks after surgery.ConclusionIntramembranous and endochondral osteogenesis take place at the site of cricoid cartilage defects treated with rhBMP‐2. Progenitor cells of cricoid perichondrium form a growth plate‐like structure similar to the epiphyseal growth plate.SignificanceThis study reveals the pattern of BMP‐2‐induced repair of airway cartilage defects.
Generic and specific quality‐of‐life measures in Taiwanese adults with sleep‐disordered breathing
Authors: Wang Pa‐Chun , Li Hsueh‐Yu , Shih Tung‐Sheng , Gliklich Richard E. , Chen Ning‐Hung , Liao Yu‐Fang 
Published: September 2006

ObjectiveTo investigate the quality‐of‐life status of Taiwanese adult patients with sleep‐disordered breathing (SDB).Study Design and SettingA prospective, quality of life survey in a tertiary referral sleep center on 94 consecutive adult SDB patients. Patients were evaluated with polysomnogram, Medical Outcome Study SF‐36 Health Survey, Snore Outcome Survey (SOS), and Epworth Sleepiness Scale (ESS).ResultsSDB patients have significantly lower scores in all 8 SF‐36 subscales (P < 0.05) than do normative Taiwan adult population. Apnea patients have lower SOS (34.5 ± 7.5 vs 40.1 ± 10.3, P = 0.005) and higher ESS scores than do simple snorers (8.8 ± 5.1 vs 11.7 ± 5.2, P = 0.03). Patients with a higher degree of sleepiness show worse performance in all dimensions of their general health status (P values 0.0005 to 0.01). Deep sleep (stage 3 + 4) is predictive of SF‐36 role: physical (β = 1.63, P = 0.04), bodily pain (β = 1.22, P = 0.01), vitality (β = 1.05, P = 0.01), subscales scores (adjusted R2 0.005 to 0.1).ConclusionSDB has considerable impact on a patient's global health status.SignificanceDaytime sleepiness, rather than apnea, is a major quality‐of‐life determinant. EBM rating: B‐2b
Does the chorda tympani nerve confer general sensation from the tongue?
Authors: Perez Ronen , Fuoco Gabriel , Dorion Joanne M. , Ho Peter H. , Chen Joseph M. 
Published: September 2006

ObjectivePatients often complain of numbness of the tongue after otologic procedures; this symptom may occur with or without taste alterations. The purpose of this study was to objectively assess possible changes in the general sensation of the tongue in patients undergoing middle ear surgery.Study Design and SettingThirty‐three individuals were included in this prospective controlled clinical study conducted at a tertiary referral center. Fifteen patients underwent middle ear surgery and 18 volunteers served as a control group. Subjects underwent objective tests to assess general sensation of the tongue before and twice after surgery.ResultsForty‐seven percent of the patients complained of numbness or tingling of the tongue shortly after surgery. In these patients, a significant reduction in sensitivities to light touch and 2‐point discrimination on the operated side were noted at that time (P < 0.01; P < 0.009 respectively). Values returned to baseline on subsequent evaluations. No sensitivity change was noted for the contralateral hemi‐tongue.ConclusionObjective changes in the general sensory function of the tongue correlated with post‐operative clinical symptoms experienced by patients. The results of this study support the notion that the chorda tympani nerve confers general sensation from the tongue.EBM rating: A‐1b
Vibratory pattern of vocal folds under tension asymmetry
Authors: Maunsell Rebecca , Ouaknine Maurice , Giovanni Antoine , Crespo Agrício 
Published: September 2006

ObjectiveThe aim of this study was to describe and analyze the vibratory pattern of vocal folds in an asymmetric situation.Study Design and SettingCricothyroid muscle unilateral action was simulated on excised larynges on an experimental bench. Increasing airflow rates were applied to achieve vocal fold vibration. Electroglottography and an optoreflectometer device allowed analysis of separate and simultaneous vocal fold vibration. Spectra of the signals were obtained for each level of airflow variation.ResultsAll experiments showed periodic vibration. A phase shift was noted between the two vocal folds. Subharmonics and biphonation were identified in all the experiments.ConclusionLax vocal folds were more susceptible to spectral changes with increasing airflow.SignificanceKnowledge of the consequences of mass, tension, and position asymmetries of the vocal folds is crucial for diagnosis making and defining therapeutic strategies in dysphonic patients. This study may contribute to the understanding of physiology of vocal fold interaction and its compensatory mechanisms.
Acetabular Fractures
Authors: Klinger Donna L. 
Published: September 2006

ABSTRACTTrauma injuries to the acetabulum and the associated pelvic region are second only to head injuries in mortality and morbidity for surgical patients. Surgeons in the past avoided exposing and stabilizing complex fractures of the acetabulum because of the intricate anatomy of the pelvic region. Recent advances in surgical techniques have increased the use of open reduction internal fixation of acetabular fractures. Early internal fixation of acetabular fractures allows rapid mobilization of severely injured patients and provides trauma patients optimal, long‐term, functional results. AORN J 61 (Jan 1995) 157–178.
Topological investigation of the ethanol/water system and its implications for the mode of action of homœopathic medicines
Authors: Singh Prem P. , Chhabra H.L. 
Published: September 2006

AbstractAvailable molar excess volumes VE and molar excess enthalpies HE data at 250°C in the ethanol (E) and Water (W) system have been analysed in terms of a graphtheoretical approach to suggest that both E and W (in the pure state) exist as equilibrium mixture of various r-meric forms, that the particular configuration that they acquire in their mixture is dictated by their relative proportions. Although E undergoes hydrophobic interactions in W, specific interactions between E and W favour their mutual dissolution. The process of succussion (or trituration) of homœopathic drugs with E (or lactose) produces potentized E or W molecules that mimic the properties of the drugs. Homœopathic medicines have been postulated to operate via electron-transfer processes in the Central Nervous System. A mode of action of homœopathic medicines, consistent with the recent concepts of chemistry and physics is proposed to explain the scientific basis of the law of similars and some other characteristic pharmacologic actions of homœopathic medicines.
Survey on the teaching of complementary medicine in British schools of pharmacy
Authors: Kayne Steven 
Published: September 2006

AbstractThe 16 UK schools of pharmacy were surveyed to investigate whether undergraduate students were exposed to teaching in complementary medicine. 56% replied positively, with course varying in length from 1–2 hours up to 20 hours. Of the 44% who replied negatively, 30% indicated that they thought they would teach the subject in the future.
A case of colitis treated with Secale
Authors: Jack R.A.F. 
Published: September 2006

Summary
Secale would appear initially to have helped her lassitude, diarrhoea, formication, calf cramps, and above all her apathy, restoring to her a sense of well-being. The further marked improvement that followed the therapeutic trial of increasing her dose of carbimazole suggests that she was still slightly thyrotoxic, and the indicated homœopathic medicine was not sufficient on its own. This case illustrates that homœopathic medicines can be of benefit when taken concurrently with conventional drugs.
Points at issue in the physics of water and homoeopathy
Authors: Ilyin V.V. , Antonchenko V.Ya. 
Published: September 2006

AbstractThe main features of a new model for associated liquids are expounded. The stability of various dissipative structures in water systems is explained by their presence in the earth's electromagnetic field and by the stabilizing processes of proton transfer along hydrogen-bonded chains in these structures. A possible connection between processes occurring in dissipative water structures and the radiation characteristics of homoeopathic preparations is shown.
Lessons learnt from an unsuccessful clinical trial of homœopathy
Authors: Jansen G.R.H.J. , Veer A.L.J.v.d. , Hagenaars J. , Kuy A.v.d. 
Published: September 2006

AbstractIn a randomized, double-blind study, the effects of individualized homœopathy in patients suffering from proctocolitis were investigated. The study was controlled against conventional therapy and placebo.Individually indicated homoœopathic medicines were prescribed in the 30c, 200c or 1,000c potencies.The researchers did not succeed in attracting sufficient numbers of participants to arrive at statistically significant conclusions. The total number of patients in the three combined groups was only 20, which was far below the target figure. The causes of this are discussed.Bowel habit and subjective parameters were assessed by a weekly health calendar. This calendar had not been previously validated. The conventional group scored best: eight out of ten patients completed the year of research and improved both with regard to their proctocolitis and their general well-being.
Implications of contaminants to scientific research in homoeopathy
Authors: Zacharias Carlos Renato 
Published: September 2006

Abstract3 sets of potentized hydroalcoholic solutions were analyzed by ultraviolet spectroscopy in order to observe changes due to the dynamization process. For the sets prepared in pharmacies, the spectra from dynamized solutions were different from those of inert solutions; for the set prepared under more rigorous conditions of cleanness, no significant difference could be noted. These results indicate the presence of contaminants in commercial homoeopathic medicines. We discuss the implications of this for scientific research.
Management of nursing in 19th-century London
Authors: Lorentzon Maria 
Published: September 2006

AbstractExamination of manuscript sources from the London Homoeopathic Hospital (LHH) 1850–1899 are set in historical context by presentation of data from the House of Lords Select Committee on Metropolitan Hospitals Report (1892)1 and review of selected items from the literature. This material shows the gradual progress in nursing practice, education and management at London hospitals.Analysis of LHH primary historical source documents (Minutes of Board Meetings,2 Minutes of Governors and Subscribers Meetings,3 Minutes of the LHH Staff Committee4 and the Medical Staff Committee5 and Clinical Notes6) show development of management and education systems in nursing. Less stress was placed on clinical practice. Significant support for development of nurse education at LHH was provided by members of the medical staff. The few references made to clinical nursing practice were recorded in the Medical Staff Committee Minutes. The strongest emphasis in all source material was on management of nursing services.Exploration of nursing management in 19th century London, in particular at the London Homoeopathic Hospital, reveals many similarities between conditions then and the present. It also provides evidence of progress in professionalization of nursing, with enhanced autonomy in education and professional practice. In this context, it is worth exploring the mode of managing nursing in 19th century voluntary hospitals and, in particular, at the London Homoeopathic Hospital.
Tetanus in children
Authors: Pai P.N. 
Published: September 2006

SummaryThis is an analysis of 260 cases of tetanus in children between 1 month and 12 years, treated with homœopathic remedies and four different types of combined therapies. The cases were graded into 5 categories according to severity and then divided into 5 groups. The results under different groups are analysed and compared. Combined therapy with Nux vom., Stram., A.T.S. and Chlorpromazine yielded the best results.The prognostic value of various factors such as mode of infection, incubation period, etc., are analysed and discussed.
Graphites—adhesion breaker
Authors: Munro C.K. 
Published: September 2006

SummaryThis is a lass with a long gynaecological history who had four separate abdominal operations when some suspicious TB glands were found. Subsequently she developed multiple adhesions which were treated conservatively. No further surgery could be planned unless life-saving in view of the further causation of adhesions.The first homœopathic remedy (Silica) had no effect. Within a week of commencing Graphites 30th she was completely well and went from strength to strength. She is still very well after about nine months.I have little doubt that Graphites transformed her life and indeed may probably have saved it.
Symptoms and treatment of whooping cough, 1980–82
Authors: English J.M. 
Published: September 2006

AbstractQuestionnaires were obtained from the parents of 71 children who contracted pertussin in 1980–82. They sought to confirm the typical clinical history of the disease, its severity, duration, method of treatment, and any effect this had on its course. They suggest that the disease is milder than it used to be and that whilst antibiotics, including erythromycin, make no significant difference to its course, homœopathic treatment reduces its duration and severity.
Does chelidonium 3x lower serum cholesterol?
Authors: Bol C.J. , Oude Luttikhuis W.M.T. , Beynen A.C. , Baumans V. 
Published: September 2006

AbstractOral administration of Chelidonium 3x twice a day was found to partly counteract the increase in serum cholesterol seen in rabbits after cholesterol feeding. After 34 days the rabbits treated with Chelidonium 3x displayed about 25% lower serum cholesterol concentrations than the controls.
Homœopathy and physiotherapy, with special reference to osteoarthropathy
Authors: Mesquita Lucia Pires 
Published: September 2006

AbstractA study was carried out to make scientific assessment of the efficacy of homœopathic treatment for osteoarthropathy. One hundred and sixty patients with this diagnosis who were attending the Physical Medicine Unit (SMFR) of the IASERJ Central Hospital were included in the study which compared the combination of physical therapy and homœopathic treatment with one of physical therapy and conventional medical treatment, to determine the limits for improvement and their probable causes.Hypotheses were tested and revealed outstanding results to the effect that 92% of patients treated with physical medicine and homœopathy could be discharged. The results confirm that homœopathy used in conjunction with physical medicine gives more rapid and lasting results in cases of osteoarthropathy.
A century of homoeopathic paediatrics
Authors: Leary Bernard 
Published: September 2006

AbstractAmong homoeopaths the idea of specialist provision for children followed the general trend. It was encouraged by the high morbidity and mortality among children due to poverty. The prevalence of tuberculosis, syphilis and the infectious fevers, together with the ignorance about hygiene of mothers of young children, were all factors of concern. Homoeopathic physicians and their supporters wished to give poor children the benefits of their system, which they believed could deal more efficaciously with the risks to their health. Homoeopathic specialist units gradually disappeared, partly due to the NHS and partly because the factors which stimulated their inception no longer applied. Homoeopathy itself became the speciality.
Growth-promoting effect of sulphur 201c in pigs
Authors: Searcy-Bernal Roberto , Soto-Avila José , Guajardo-Bernal Germán 
Published: September 2006

AbstractIn a blind, placebo-controlled trial, a homoeopathic dynamized dilution of Sulphur 201c was given orally to pregnant sows every 10 days. No significant difference was detected between the birth weight of litters (39 piglets) of treated sows and control litters (40 piglets). On day 30 statistically significant differences were observed both in the final weight of litters, mean total and daily weight gain.
Homoeopathic treatment of attention deficit hyperactivity disorder
Authors: Lamont John 
Published: September 2006

Abstract43 children with attention deficit hyperactivity disorder (ADHD) were alternately assigned to either placebo or homoeopathic treatment in a double blind, partial crossover study to determine the effectiveness of homoeopathy for this disorder. Medicines or placebos were given to parents or carers and were administered to children by the parent or carers. After 10 days children in the placebo group were given homoeopathic medicines. Statistical comparisons were made on the basis of parent or carer ratings of ADHD behaviour before and after treatment. Scores for subjects initially in the placebo group were compared with those initially in the homoeopathic group; and scores for subjects initially in the placebo group were compared with scores for the same subjects after they received homoeopathic medicine. Statistically significant differences were found for both comparisons, supporting the hypothesis that homoeopathic treatment is superior to placebo treatment for ADHD.
Patients at the London Homoeopathic Hospital, 1889–1923
Authors: Bosanquet Anna , Lorentzon Maria 
Published: September 2006

AbstractSocial profiles and clinical characteristics of patients at the London Homoeopathic Hospital in the period 1889–1923 are described, based on documentary research. The main sources are 300 volumes of manuscript case notes from this period, discovered in the LHH basement in 1992. Annual hospital reports from 1899 and 1919 provide further illustrative material. Examination of these documents revealed rich information related to medical diagnoses and outcomes of hospital treatment, length of hospital stay and social characteristics such as occupation. Changes over time were identifiable and this is of special interest as the period covered the First World War and an era of marked change in both traditional and homoeopathic medical practice.
Antineoplastic effects of 4 homoeopathic medicines
Authors: Maliekal Thobias P. 
Published: September 2006

AbstractThe present work is concerned with the study of the antitumour activities of the 4 homoeopathic medicines Kali muriaticum, Phytolacca decandra, Hydrastis canadensis and Zincum metallicum in murine models. The experiments showed that the administration of Zincum met 200x considerably increased the life span of the tumour-bearing mice.