bluuebunny/crossref_metadata_2025_split huggingface dataset:
Optimal Price Discrimination for Randomized Mechanisms
Authors: Ko Shao-Heng , Munagala Kamesh 
Published: March 2024

We study the power of price discrimination via an intermediary in bilateral trade, when there is a revenue-maximizing seller selling an item to a buyer with a private value drawn from a prior. Between the seller and the buyer, there is an intermediary that can
segment
the market by releasing information about the true values to the seller. This is termed signaling, and enables the seller to price discriminate. In this setting, Bergemann et al. [
7
] showed the existence of a signaling scheme that simultaneously raises the optimal consumer surplus, guarantees the item always sells, and ensures the seller’s revenue does not increase.

Our work extends the positive result of Bergemann et al. to settings where the type space is larger, and where the optimal auction is randomized, possibly over a menu that can be exponentially large. In particular, we consider two settings motivated by budgets: The first is when there is a publicly known budget constraint on the price the seller can charge [
12
] and the second is the FedEx problem [
19
] where the buyer has a private deadline or service level (equivalently, a private budget that is guaranteed to never bind). For both settings, we present a novel signaling scheme and its analysis via a continuous construction process that recreates the optimal consumer surplus guarantee of Bergemann et al. and further subsumes their signaling scheme as a special case. In effect, our results show settings where even though the optimal auction is randomized over a possibly large menu, there is a market segmentation such that for each segment, the optimal auction is a simple posted price scheme where the item is always sold.

The settings we consider are special cases of the more general problem where the buyer has a private budget constraint in addition to a private value. We finally show that our positive results do not extend to this more general setting, particularly when the budget can bind in the optimal auction, and when the seller’s mechanism allows for all-pay auctions. Here, we show that any efficient signaling scheme necessarily transfers almost all the surplus to the seller instead of the buyer.
Round Table Discussion on Optimal Clinical Trial Design in Precursor Multiple Myeloma
Authors: Ghobrial Irene M. , Gormley Nicole , Kumar Shaji K. , Mateos Maria-Victoria , Bergsagel P. Leif , Chesi Marta , Dhodapkar Madhav V. , Dispenzieri Angela , Fonseca Rafael , Getz Gad , Kastritis Efstathios , Kristinsson Sigurdur Y. , Martinez-Climent Jose Angel , Manier Salomon , Marinac Catherine R. , Maura Francesco , Morgan Gareth J. , Davies Faith E. , Nadeem Omar , Nuvolone Mario , Paiva Bruno , O'Donnell Elizabeth , Prosper Felipe , Shah Urvi A. , Sklavenitis-Pistofidis Romanos , Sperling Adam S. , Vassiliou George S. , Munshi Nikhil C. , Castle Philip E. , Anderson Kenneth C. , San Miguel Jesus F. 
Published: March 2024

Summary:
While the current approach to precursor hematologic conditions is to “watch and wait,” this may change with the development of therapies that are safe and extend survival or delay the onset of symptomatic disease. The goal of future therapies in precursor hematologic conditions is to improve survival and prevent or delay the development of symptomatic disease while maximizing safety. Clinical trial considerations in this field include identifying an appropriate at-risk population, safety assessments, dose selection, primary and secondary trial endpoints including surrogate endpoints, control arms, and quality-of-life metrics, all of which may enable more precise benefit–risk assessment.
Health Care Access Dimensions and Racial Disparities in End-of-Life Care Quality among Patients with Ovarian Cancer
Authors: Karanth Shama , Osazuwa-Peters Oyomoare L. , Wilson Lauren E. , Previs Rebecca A. , Rahman Fariha , Huang Bin , Pisu Maria , Liang Margaret , Ward Kevin C. , Schymura Maria J. , Berchuck Andrew , Akinyemiju Tomi F. 
Published: March 2024

Abstract

This study investigated the association between health care access (HCA) dimensions and racial disparities in end-of-life (EOL) care quality among non-Hispanic Black (NHB), non-Hispanic White (NHW), and Hispanic patients with ovarian cancer. This retrospective cohort study used the Surveillance, Epidemiology, and End Results–linked Medicare data for women diagnosed with ovarian cancer from 2008 to 2015, ages 65 years and older. Health care affordability, accessibility, and availability measures were assessed at the census tract or regional levels, and associations between these measures and quality of EOL care were examined using multivariable-adjusted regression models, as appropriate. The final sample included 4,646 women [mean age (SD), 77.5 (7.0) years]; 87.4% NHW, 6.9% NHB, and 5.7% Hispanic. In the multivariable-adjusted models, affordability was associated with a decreased risk of intensive care unit stay [adjusted relative risk (aRR) 0.90, 95% confidence interval (CI): 0.83–0.98] and in-hospital death (aRR 0.91, 95% CI: 0.84–0.98). After adjustment for HCA dimensions, NHB patients had lower-quality EOL care compared with NHW patients, defined as: increased risk of hospitalization in the last 30 days of life (aRR 1.16, 95% CI: 1.03–1.30), no hospice care (aRR 1.23, 95% CI: 1.04–1.44), in-hospital death (aRR 1.27, 95% CI: 1.03–1.57), and higher counts of poor-quality EOL care outcomes (count ratio:1.19, 95% CI: 1.04–1.36). HCA dimensions were strong predictors of EOL care quality; however, racial disparities persisted, suggesting that additional drivers of these disparities remain to be identified.

Significance:
Among patients with ovarian cancer, Black patients had lower-quality EOL care, even after adjusting for three structural barriers to HCA, namely affordability, availability, and accessibility. This suggests an important need to investigate the roles of yet unexplored barriers to HCA such as accommodation and acceptability, as drivers of poor-quality EOL care among Black patients with ovarian cancer.
Hubungan Tingkat Kecemasan dengan Angka Kejadian Nokturia pada Mahasiswa/i Fakultas Teknologi Pertanian Universitas Brawijaya selama Pandemi COVID-19
Authors: Pradyaputri Naura Shafa , Daryanto Besut , Sagita Zendy 
Published: March 2024

Pendahuluan: Nokturia merupakan gejala paling umum dan mengganggu pada gangguan saluran kemih bagian bawah. Dampak nokturia dirasakan lebih besar pada usia muda khususnya mahasiswa yang dapat menyebabkan penurunan performa akademik. Sebuah penelitian mengungkapkan bahwa kecemasan sering terjadi secara bersamaan dengan nokturia dan memiliki hubungan dua arah.
Tujuan: Penelitian ini bertujuan untuk mengetahui prevalensi serta hubungan tingkat kecemasan dengan angka kejadian nokturia pada mahasiswa/i teknologi pertanian selama pandemi COVID-19.
Metode: Penelitian observasional analitik dengan desain cross sectional. Kuisioner Google form berisi pertanyaan data karakteristik mahasiswa, kuesioner ICIQ-N berisi frekuensi nokturia serta skor mengganggu, dan kuesioner ZSAS untuk tingkat kecemasan. Analisis data menggunakan uji Chi Square untuk menganalisis hubungan antara tingkat kecemasan dan nokturia.
Hasil: Hasil diperoleh bahwa terdapat hubungan yang tidak signifikan antara tingkat kecemasan (p=0.307). Nokturia merupakan gejala yang sering dialami oleh mahasiswa. Skor mengganggu meningkat seiring dengan tingkat keparahan nokturia.
Kesimpulan: Terdapat hubungan yang lemah antara tingkat kecemasan dengan nokturia.
Unveiling Modern Strategies for Diagnosing and Treating Grave Orbitopathy
Authors: Ujianto Michelle , Sari Felita , Rakhman Muhammad Farid 
Published: March 2024

Graves' Orbitopathy (GO), also known as thyroid eye disease or thyroid-associated orbitopathy is characterized by inflammation, ocular muscle hypertrophy, adipogenesis, and oedema (due to glycosaminoglycan accumulation). This condition leads to remodeling, tissue expansion, and/or fibrosis within the fibroadipose tissue or extraocular muscles of the orbit. GO manifests as an extrathyroidal aspect of autoimmune thyroid diseases in both Grave's disease (GD) and Hashimoto's thyroiditis.
The pathophysiological foundation of GO entails the infiltration of B cells, T cells, and CD34+ fibroblasts in the orbit. B cells generate IGF (insulin-like growth factor), wherein IGF and TRab (Thyroid-Receptor antibodies) stimulate the IGF receptor complex and thyrotropin receptor (respectively) on the surface of CD34+ cells which triggers orbital tissue expansion, orbital protrusion, optic nerve compression, and eyeball displacement, resulting in exophthalmos.
GO progress through an active phase (characterized by inflammation with visible manifestations), followed by a plateau phase (stabilization of GO manifestations), and a gradual resolution of distinctive residual signs and symptoms (inactive phase). This entire process spans between 18-24 months in untreated patients, where disease manifestations significantly depend on the phase during which the disease is identified.
GO therapy is intended to shorten the active phase and supress its residual eye manifestations during the inactive phase. In general, GO therapy is categorized into general and disease severity-specific approaches.
GO therapy often falls short of providing satisfactory results, prompting need of surgery to address lingering clinical manifestations. This review presents the latest insights into the pathogenesis and treatment of GO for better management and outcomes.
Left Atrial Strain Predicts Subclinical Atrial Fibrillation Detected by Long-term Continuous Monitoring in Elderly High-Risk Individuals
Authors: Olsen Flemming Javier , Diederichsen Søren Zöga , Jørgensen Peter Godsk , Jensen Magnus T. , Dahl Anders , Landler Nino Emanuel , Graff Claus , Brandes Axel , Krieger Derk , Haugan Ketil , Køber Lars , Højberg Søren , Svendsen Jesper Hastrup , Biering-Sørensen Tor 
Published: March 2024

BACKGROUND:
Left atrial (LA) speckle tracking provides detailed information on atrial function. Its utility for predicting subclinical atrial fibrillation (SCAF) is unclear. Therefore, we sought to investigate whether LA strain measures could predict SCAF detected by long-term continuous rhythm monitoring.

METHODS:
This was an echocardiographic substudy of the LOOP study, where elderly at risk of stroke were randomized to receive a loop recorder (Reveal LINQ) or control. Participants who received a loop recorder were included in this analysis. Echocardiography included LA reservoir, conduit, and contraction strain. Participants were followed with continuous rhythm monitoring for SCAF (≥6 minutes). Cox proportional hazards regression was applied to adjust for atrial fibrillation risk factors.

RESULTS:

In total, 956 participants were eligible for analysis. Median continuous rhythm monitoring was 35 months (IQR, 20–40 months), during which 278 (29%) were diagnosed with SCAF. The mean age was 74 years, 56% were male, median CHA
2
DS
2
-VASc-score was 4. LA reservoir strain was an independent predictor of SCAF after multivariable adjustments (HR, 1.04 [1.02–1.05], per 1% decrease) and so was contraction strain. The findings were unchanged in competing risk analyses and in participants with normal LA size and diastolic function. Participants with low reservoir strain (<33%) had a significantly higher risk of SCAF compared with those with high reservoir strain (incidence rate, 14.5 [12.4–16.9] versus 9.8 [8.2–11.8] events/100 person-years). The same was noted for low versus high contraction strain.

CONCLUSIONS:
LA reservoir and contraction strain are independent predictors of SCAF in elderly at risk of stroke. This also applies to individuals with normal LA size and diastolic function.

REGISTRATION:

URL:
https://www.clinicaltrials.gov
; Unique identifier: NCT02036450.
Author mentions in science news reveal widespread disparities across name-inferred ethnicities
Authors: Peng Hao , Teplitskiy Misha , Jurgens David 
Published: March 2024

Abstract
Media outlets play a key role in spreading scientific knowledge to the public and raising the profile of researchers among their peers. Yet, how journalists choose to present researchers in their stories is poorly understood. Using a comprehensive data set of 223,587 news stories from 288 US outlets reporting on 100,486 research papers across all areas of science, we investigate whether authors’ ethnicities, as inferred from names, are associated with whether journalists explicitly mention them by name. We find substantial disparities in mention rates across ethnic names. Researchers with non-Anglo names, especially those with East Asian and African names, are significantly less likely to be mentioned in their news stories, even with extensive controls for author prestige, semantic content, news outlets, publication venues, and research topics. The disparities are not fully explained by affiliation locations, suggesting that pragmatic factors play only a partial role. Furthermore, among US-based authors, journalists more often use authors’ institutions instead of names when referring to non-Anglo-named authors, suggesting that journalists’ rhetorical choices are also key. Overall, this study finds evidence of ethnic disparities in how often researchers are described in the media coverage of their research, likely affecting thousands of non-Anglo-named scholars in our data alone.
An Unfinished Quest: David J. Bosch’s Legacy Concerning the Relationship between Evangelism and Service
Authors: Jansson Andreas C. 
Published: March 2024

Abstract
David Bosch calls the relationship between evangelism and service “one of the thorniest areas” in Missiology. He analyses and criticises Western dichotomic thinking, which tends to contrast evangelism and service, word and deed, soul and body. This is the source of what Bosch calls “a battle for supremacy” between evangelism and service, and during his own life, he committed himself to “a personal quest” for a non-dichotomic understanding of evangelism and service. The present article presents Bosch’s reflection of the relationship between evangelism and service over a period of more than two decades. It analyses his approaches in overcoming the Western dichotomic thinking in this regard and argues that Bosch’s “personal quest” remained an unfinished quest, which we are invited to join. This can be seen as his legacy concerning the relationship between evangelism and service.
Translating the Gospel or Christianity?
Authors: Kaunda Chammah J. 
Published: March 2024

Abstract
This article employs Pentecostal mediation to engage the divergent views of Mbiti and Sanneh on the question of what translates between ‘the Gospel’ and ‘Christianity’. This approach is dialectical and dialogical imaginative Pentecostal third space inquiry which affirms paradoxical meaning makings. It is also embedded in the pneumatic principle as the power behind translatability. This approach demonstrates that both scholars were seeking to make sense of how Christianity can be said to have become a distinctive African religious reality in its practices, beliefs, and theological expressions. It concludes that the translatable Gospel is a Christian-producing Gospel and a Christian-producing Gospel is a translating and translatable Christianity. This frame of thinking makes sense, at least, within Pentecostal theological and missiological thought in which, ontologically, the Gospel and Christianity are already translated.
Feminist-Pentecostal Hermeneutics
Authors: Gregory Jeanetta N.B. 
Published: March 2024

Abstract
This article explores an emerging hermeneutic of participation arising from the feminist-Pentecostal dialogue. For many, Pentecostal and feminist hermeneutics appear incompatible. Further examination reveals the possibility of dialogue originating from their pneumatological, canonical, narratival, and anthropological hermeneutical convictions. This is reinforced through shared theological values, anthropological convictions, and common history. This feminist-Pentecostal dialogue yields a hermeneutic of participation marked by orthodoxy, orthopathy, and orthopraxy. Ultimately, this hermeneutic of participation fosters discipleship and the flourishing of the Church.
The stoicheiôsis of Proclus’ Elements of Theology
Authors: Troncoso Guillermo Javier Ruz 
Published: March 2024

Abstract
This article suggests a novel approach to the study of the argumentative structure of Proclus’ Elements of Theology (ET). Instead of studying it through the prism of the Elements of Euclid (EG), this novel approach proposes an evaluation of ET’s argumentative structure based on Proclus’ reflections about the genre of stoicheiôsis and the methods of dialectic and geometry. Thus, I argue that studies under the suggested form of evaluation should standardize the conceptual framework of their analyses about the features of ET’s argumentative structure, explicating their relevance for the interpretation of the text’s system of logical relations. Moreover, this article presents some examples of editorial enhancements made by editors of ET clarifying the argumentative structure of the text. With these examples, I will show how these enhancements help us clarify the argumentative structure of ET.
Mere Appearance or More? A Crux at Phaedo 74b–c Revisited
Authors: Bitetti Putzer Ryan 
Published: March 2024

Abstract
The non-identity argument at Phaedo 74b–c is among the most studied and disputed arguments in Plato’s dialogues. In the passage, equality is distinguished from perceptible equals insofar as the latter sometimes appear (phainetai) unequal. A long-standing crux is whether the distinction concerns perceptible equals’ merely appearing unequal or actually being so. A fresh approach to the construal of the verb phainomai is taken here and shown to favor the latter view, thereby securing a stronger argument for non-identity.
Spatial and Temporal Variation of Subseasonal-to-Seasonal (S2S) Precipitation Reforecast Skill across the CONUS
Authors: Levey J. R. , Sankarasubramanian A. 
Published: March 2024

Abstract
Precipitation forecasts, particularly at subseasonal-to-seasonal (S2S) time scale, are essential for informed and proactive water resource management. Although S2S precipitation forecasts have been evaluated, no systematic decomposition of the skill, Nash–Sutcliffe efficiency (NSE) coefficient, has been analyzed toward understanding the forecast accuracy. We decompose the NSE of S2S precipitation forecast into its three components—correlation, conditional bias, and unconditional bias—by four seasons, three lead times (1–12, 1–22, and 1–32 days), and three models, European Centre of Medium-Range Weather Forecasts (ECMWF), National Centers for Environmental Prediction’s (NCEP) Climate Forecast System (CFS) model, and Environment and Climate Change Canada (ECCC), over the conterminous United States (CONUS). Application of a dry threshold, removal of grid cells with seasonal climatological precipitation means below 0.01 in. per day, is important as the NSE and correlations are lower across all seasons after masking areas with low precipitation values. Further, a west-to-east gradient in S2S forecast skill exists, and forecast skill was better during the winter months and for areas closer to the coast. Overall, ECMWF’s model performance was stronger than both ECCC and NCEP CFS’s performance, mainly for the forecasts issued during the fall and winter months. However, ECCC and NCEP CFS performed better for the forecast issued during the spring months and for areas further from the coast. Postprocessing using simple model output statistics could reduce both unconditional and conditional biases to zero, thereby offering better skill for regimes with high correlation. Our decomposition results show that efforts should focus on improving model parameterization and initialization schemes for climate regimes with low correlation.
What are optimum cycles for immediate primary closure of large cutaneous defects?
Authors: Li Gang , Huang Yajun , Song Mingzhi , Lu Ming 
Published: March 2024

Background: In the reconstruction of large complex cutaneous wounds, a myriad of mechanical devices has been designed to facilitate primary wound closure. However, there is a dearth of studies elucidating how best to achieve optimum use and efficiency of skin stretching (SS) when using the device for immediate primary closure of defects. Methods: Skin defect wounds (7 × 7 cm) were prepared on the back of three Bama miniature pigs. A total of 15 cycles of SS (cycle loading) were subsequently performed on the skin edges of the wound by EASApprox® SS system. Then, the changes in equidistant points were recorded after each cycle. After the SS test, all wounds were sutured under low tension. Results: Skin elongation was observed at all equidistant points on the back wounds of three Bama miniature pigs. Up to an additional 1.10 to 3.75 cm of tissue was garnered. The maximum skin elongation was typically achieved within eight cycles of stretching and relaxation. Beyond this range, additional stretching cycles did not result in further skin extension. Conclusion: There may be a close link between mobilization range and the times of acute cyclic stretching (cycle loading) during the process of primary wound closure. However, larger studies are required to further evaluate the accuracy and effectiveness.
The reliability, validity and clinical utility of the Clinical Outcomes in Routine Evaluation – ten-item version (CORE-10) in post-acute patients with stroke
Authors: Steverson Tom , Marsden Joseph , Blake Joshua 
Published: March 2024

Objective To explore the validity, reliability, and clinical utility of the Clinical Outcomes in Routine Evaluation – ten-item version (CORE-10: a ten-item questionnaire designed to measure psychological distress) in a stroke inpatient sample and calculate reliable and clinically significant change scores. Setting A post-acute stroke rehabilitation ward in the East of England. Participants A total of 53 patients with stroke, capable of completing the CORE-10 as part of their routine clinical assessment. Exclusion criteria included moderate to severe aphasia and/or alexia. Main measures Alongside the CORE-10, the Patient Health Questionnaire – 9, the Hospital Anxiety and Depression Scale, the Centre for Epidemiological Studies-Depression Scale, and the Beck Depression Inventory Second Edition were used as concurrent measures. Results To assess reliability, the internal consistency and test–retest reliability of the CORE-10 were calculated. The average number of days between CORE-10 test–retest administrations was 2.84 ( SD = 3.12, Mdn = 1). Concurrent validity was assessed by examining correlations between the CORE-10 and comparable measures, and clinical utility was assessed using the criteria of Burton and Tyson (2015). The internal consistency (Cronbach’s alpha) for the CORE-10 was .80, and test–retest reliability interclass correlation coefficient was .81. Total score correlations between the CORE-10 and concurrent measures ranged from r = .49 to r = .89. The CORE-10 achieved the maximum score (i.e. 6/6) on criteria for clinical utility. Calculations demonstrated a reliable change index of nine points and a clinically significant change cut point of 12 on the CORE-10. Percentiles for CORE-10 total scores are reported. Conclusions This study provides preliminary support for the CORE-10 as a valid and reliable measure that has clinical utility for screening distress in inpatients with stroke.