bluuebunny/crossref_metadata_2025_split huggingface dataset:
Histopathology of the soft parts in 50 patients with malignant external otitis
Authors: Bernheim J. , Sade J. 
Published: November 2007

AbstractReports concerning the lesions of the skin coverage of the external ear canal in malignant external otitis (M.E.O.) are very few. To evaluate this problem, we studied the skin lesions of 45 skin biopsies from 40 M.E.O. patients, 23 from regions covering the osseous part of the ear structure, seven from the cartilaginous part of the external canal and 15 from both parts. The epidermis was normal in nine, thickened in 16, with acanthotic thickening and pseudoepitheliomatous hyperplasia in 20. In the dermis the amount of collagen was normal, but it was infiltrated by the inflammatory process. Acute inflammation was observed in 16 biopsies, subacute in 23, chronic in six. A mixture of acute and chronic changes was present in 18 biopsies. No major abnormalities of the vasculature could be detected. The distinguishing pathological feature of M.E.O. concerns the typical topographic distribution of the inflammation in the osseous part of the external ear canal.
Sensorineural deafness associated with IgA nephropathy
Authors: Ataya N. L. 
Published: November 2007

AbstractIgA nephropathy is an immune complex glomerulonephritis in which examination of the renal biopsy by immu-nofluorescence reveals IgA as the predominant antibody deposited in the glomerular mesangium (Clarkson et al., 1984). It was first described by Berger in 1969. The disease is more common in males and occurs generally during the second or third decades of life (Emancipator et al., 1985). A case of established IgA nephropathy with subsequent onset of sensorineural deafness is described.
Verrucous carcinoma of the maxillary antrum
Authors: Bacon M. P. , Chevretton E. B. , Slack R. W. T. , MacLeod T. I. F. 
Published: November 2007

AbstractVerrucous carcinoma is a rare type of squamous cell carcinoma which is most often seen in the oral cavity and larynx. This paper describes a case of verrucous carcinoma of the maxillary antrum, a site in which this tumour has been described on only two previous occasions in the English language literature.
Mucoepidermoid carcinoma of the larynx
Authors: Cumberworth V. L. , Narula A. , MacLennan K. A. , Bradley P. J. 
Published: November 2007

AbstractWe report two cases of poorly differentiated mucoepidermoid carcinoma of the larynx which both remain well after surgical management. The first underwent a radical neck dissection for recurrent disease following radiotherapy and the second a total laryngectomy with elective post-operative radiotherapy.Although well differentiated (‘low grade’) mucoepidermoid tumours of the larynx may respond to radiotherapy surgical management is generally recommended for all grades of such tumours especially for poorly differentiated (‘high grade’) tumours. Elective post-operative radiotherapy is often advocated for high grade tumours; radical neck dissection is generally undertaken only in the presence of lymphadenopathy, although elective radical neck dissection has been proposed for high grade tumours. These cases emphasise the value of comprehensive surgical management for this condition.Such laryngeal tumours are difficult to diagnose histologically from biopsy and are often initially reported as squamous cell carcinoma.
Nontraumatic intracavernous carotid aneurysm presenting with epistaxis
Authors: Chandy M. J. 
Published: November 2007

AbstractA patient with an intracavernous carotid aneurysm usually presents with symptoms and signs of a space occupying lesion, producing one of a variety of types of cavernous sinus syndromes (Jefferson, 1938). Epistaxis is an unusual feature in these patients and when present is nearly always associated with a traumatic aneurysm (Mahmoud, 1979). There are only two reported cases of non-traumatic intracavernous carotid aneurysms presenting with epistaxis and diagnosed during the lifetime of the patient (Troupp, 1962; Labayle and Legent, 1964). The authors present a third such case. The importance of considering aneurysms in the differential diagnosis of epistaxis is emphasised. The radiological investigations and management of these patients is discussed.
Influence of the mode of preparation on the distortion and consistency of homologous costal cartilage implants
Authors: Adlington P. , Anscombe A. J. , Joshi J. B. 
Published: November 2007

AbstractNasal implants of autologous costal cartilage have an undesirable tendency to distortion. This tendency may be reduced by the process of devitalization, which occurs in the preparation of homologous costal cartilage for storage in a tissue bank. Anin vitrostudy has been undertaken, utilizing five common methods of cartilage preparation (cialit, ethyl alcohol, formalin, glutaraldehyde and irradiation) to determine whether there is any significant variation in the degree of distortion which occurred and any variation in cartilage consistency. We conclude that all of the methods evaluated would produce banked homologous costal cartilage with an equally low incidence of distortion but implants are less readily carved from cartilage stored in cialit.
Metastasis to the temporal bone, secondary to carcinoma of the bladder
Authors: Saldanha C. B. R. , Bennett J. D. C. , Evans J. N. G. , Pambakian H. 
Published: November 2007

AbstractAn 80-year-old man was seen in the clinic with a two month history of pain, bleeding and deafness in his left ear; accompanied by a left facial palsy. Six months earlier, anaplastic carcinoma of the bladder had been diagnosed and treated with radiotherapy. On examination there was a mass in his left external auditory canal and VII, VIII, IX and X left cranial nerve palsies. Histology of a biopsy was identical with his original bladder tumour. He received a course of palliative radiotherapy but died shortly after. Post-mortem demonstrated the left temporal bone metastasis extending into the middle and posterior cranial fossae. There was no evidence of residual bladder tumour, or other primary tumour. Temporal bone metastases are probably more common than generally thought. Presentations like this may become more common as cancer therapy improves, with patients surviving longer and presenting later with metastatic disease.
Ophthalmic considerations in fronto-ethmoidal mucocoeles
Authors: Lund Valerie J. , Rolfe Muriel E. 
Published: November 2007

AbstractThe pre-and post-operative ophthalmic consequences of fronto-ethmoidal mucocoeles are considered in a prospective series of 22 patients. Proptosis, lateral and inferior displacement, diplopia and restriction of ocular mobility were the commonest presenting problems. Following external fronto-ethmoidectomy, proptosis and displacement resolved completely in the majority of patients. One third of patients experienced a transient exacerbation of diplopia but this resolved in most patients. Persistent diplopia occurred in seven patients and required medical correction in four and surgery in one. This was due in all cases to underaction of the superior oblique muscle and probably to backward displacement of the trochlea which may be avoided by careful surgical re-attachment.
Second primary tumour following retinoblastoma
Authors: Berridge D. C. , Hitchcock A. , Bradley P. J. , Kapila L. 
Published: November 2007

AbstractReported is a child who at the age of 18 months had presented with a left retinoblastoma. The lesion had involved the optic nerve (Stage IV), and was successfully treated by enucleation and radiotherapy. The radiation field did not include the mandible or the submandibular triangle. He was followed up until he left the area aged 11 years. He represented aged 12 years with a progressive swelling of the left submandibular gland. Histology of the surgically excised submandibular gland revealed a mucoepidermoid carcinoma of the submandibular gland. This case highlights the need for continual surveillance in survivors of retinoblastoma, as second primary tumours occur both within and outside of previous radiation fields. The clinical association between retinoblastoma and mucoepidermoid carcinoma of the submandibular gland has not been previously reported.
Atypical thyroglossal duct cyst
Authors: Cumberworth V. L. , Bradley P. J. 
Published: November 2007

AbstractThyroglossal duct cysts most frequently present in childhood as a painless midline swelling of the neck. Uncommonly, these embryonal remnant cysts present clinically in adult life. The majority of adults with thyroglossal duct cysts present with a swelling at the level of the thyrohyoid membrane. On rare occasions, a thyroglossal duct cyst can present with more sinister symptoms, such as hoarseness, dysphagia and dyspnoea. On these occasions, the pre-operative clinical and investigative diagnosis remains in doubt until histology is available.
Synchronous extra-parotid Warthin's tumour
Authors: Nishikawa H. , Kirkham N. , Hogbin B. M. 
Published: November 2007

AbstractWarthin's tumour (also known as adenolymphoma or papillary cystadenoma lymphomatosum) is benign and accounts for 12 per cent of all neoplasms of the parotid gland. A case of extra-parotid Warthin's tumour occurring synchronously in a peri-parotid lymph node is described. This is not a metastatic phenomenon and occurs as a result of salivary gland inclusions of local lymph nodes during the embryological development of the parotid. Extra-parotid Warthin's tumour should be regarded as a benign incidental finding and the prognosis is excellent.
Contralateral auditory brainstem response abnormalities in acoustic neuroma
Authors: Moffat D. A. , Baguley D. M. , Hardy D. G. , Tsui Y. N. 
Published: November 2007

AbstractContralateral Auditory Brainstem Response (ABR) findings in a series of 79 patients with unilateral acoustic neuroma are presented. Sixty-four patients (81 per cent) had a normal contralateral ABR, thirteen (16.4 per cent) had latency abnormalities contralaterally and in two patients (206 per cent) no consistent responses could be recorded despite good hearing. Abnormalities in the contralateral ABR were analysed and five patients had abnormal III-V interwave intervals, in seven patients the I-III intervals were abnormal and in one patient, only the fifth wave was present and of abnormal latency. The tumour size was assessed by computed axial tomography (CT) and the relationship between tumour size and contralateral ABR findings established. Large tumours (>2.5 cm.) were associated with contralateral ABR abnormalities in 25.6 per cent of the patients, medium tumours (1.0-2.5 cm.) with ABR abnormalities in 14 per cent and there were no abnormalities in the small group (intracanalicular). The implications for interpretation of ABR recordings contralateral to an acoustic neuroma are discussed in relation to brainstem compression and its effect on the wave generator sites.
Clofazimin in the treatment of scleroma
Authors: Shehata M. A. , Salama A. M. 
Published: November 2007

AbstractScleroma is a chronic progressive granulomatous disease predominantly affecting the mucous membrane of the upper respiratory tract, endemic in temperate and tropical zone countries including Egypt. Many patients in early stages respond to medical treatment while others do not. In these patients an antileprotic agent Clofazimin (Lamprene®) was tried in 76 patients and the therapeutic results are very promising, especially for the early stages of the disease.
Traumatic middle ear lesions. Fracture of the malleus handle, aetiology, diagnosis and treatment
Authors: Pedersen C. Brahe 
Published: November 2007

AbstractTraumatic middle ear lesions are quite common but only seldom mentioned in the literature; an isolated fracture of the handle of the malleus seems to be extremely rare. The appearance of two patients with an isolated fracture of the haddle of the malleus within one year might indicate that this type of lesion should be considered more frequently. The traumatic aetiology, symtoms, diagnosis and treatment of this lesion is described and is illustrated by two cases.
Total glossectomy: reconstruction and rehabilitation
Authors: Tiwari R. M. , Greven A. J. , Karim A. B. M. F. , Snow G. B. 
Published: November 2007

AbstractPatients with carcinoma of the tongue including the base of the tongue who underwent total glossectomy in a period of just over ten years since January 1979 have been reviewed. Total glossectomy may be indicated as salvage surgery or as a primary procedure. The larynx may be preserved or may have to be sacrificed depending upon the site of the lesion. When the larynx is preserved the use of laryngeal suspension facilitates early rehabilitation and preserves the quality of life to a large extent. Cricopharyngeal myotomy seems unnecessary.
Alveolar soft part sarcoma of the tongue
Authors: Cetik F. , Ozsahinoglu C. , Kivanc F. , Secinti E. 
Published: November 2007

AbstractIn this report a 13-year-old girl with characteristic clinical and pathological features of alveolar soft part sarcoma of the tongue is presented. Alveolar soft part sarcoma is a rare malignant tumor of unknown origin. Forty eight cases of alveolar soft part sarcoma have so far been reported in the head and neck region. Median survival reported for all sites of the body is 79 months following various modes of therapy. In this case, the treatment was surgical excision of the mass combined with radiotherapy and chemotherapy. The patient has been asymptomatic for the past 12 months.
Facial schwannoma without facial paralysis
Authors: Sharp J. F. , Kerr A. I. G. , Carder Pauline , Sellar R. J. 
Published: November 2007

AbstractA 64-year-old man with right aural discharge presented complaining of progressive deafness. Other otological symptoms were absent and specifically there was no seventh nerve paresis. A right aural polyp was identified and biopsied. Histology showed the polyp to be a schwannoma.Subsequent temporal bone computed tomography showed expansion of the distal facial canal. At operation, the schwannoma filled the middle ear cleft and extended from the genu to the region of the stylomastoid foramen. The floor of the middle ear had been eroded, exposing the jugular bulb.Facial paresis is the usual presenting feature of a facial schwannoma, while deafness, ageusia and reduced lacrimation are variable, dependent upon the site of the lesion. The absence of facial palsy as a presenting feature is very rare and this case illustrates the need for histological examination of all abnormal aural material.
Congenital subglottic fibromatosis
Authors: O'Connell Janet E. , Raafat Faro , Proops David 
Published: November 2007

AbstractBenign tracheal tumours are uncommon in adults and rare in children. According to several extensive reviews, fibromas are the second most common benign tumour to occur in the trachea. (Gilbert et al., 1949, 1953).In our review of the literature, 197 adult cases of fibromas have been reported and 23 in children. However only one previous report of a congenital subglottic fibroma exists. (Tsui and Lore 1975). No previous case with a late onset vocal cord palsy has been reported.
Management of the inflammatory aural polyp
Authors: Williams S. Rhys , Robinson P. J. , Brightwell A. P. 
Published: November 2007

AbstractInvestigation into the underlying disease causing an aural polyp is often hampered when the polyp itself obscures the tympanic membrane. This retrospective analysis of 65 patients undergoing aural polypectomy was carried out to identify and predictive factors for underlying cholesteatoma and to determine a correct management stratergy for aural polyps. The duration of symptoms, size of polyp, size of conductive component of hearing loss and bacteriology of otorrhoea were unhelpful as predictors of the underlying disease. Radiological evidence of bony erosion of the mastoid is a useful sign of cholesteatoma when present.Aural polypectomy resulted in 58.3 per cent of ears becoming inactive. It is proposed that aural polypectomy and histological assessment should be employed as initial treatment with mastoid exploration reserved for those ears thus identified as high risk for cholesteatoma.
Treatment of combined subglottic and critically low tracheal stenoses secondary to burn inhalation injury
Authors: Timon C. I. , McShane D. , McGovern E. , Walsh M. 
Published: November 2007

AbstractWe report a case of combined severe subglottic and lower tracheobronchial stenoses after an inhalation burn injury. The patient was successfully treated by the insertion of a bifurcated silicone rubber stent. The proximal limb of the silicone tube was used to stent the subglottic stenosis after it had been resected, a treatment option not previously reported. It is speculated that the diffuse airway damage resulted from a combination of thermal injury, mechanical trauma and infection. The relatively late symptomatic presentation of the lower tracheal stricture is stressed and the treatment options discussed.
Sialadenoma papilliferum of the parotid gland
Authors: Kronenberg J. , Horowitz A. , Leventon G. 
Published: November 2007

AbstractSialadenoma papilliferum is a rare, benign exophytic tumour of salivary glands. The preferred site of this tumour is usually the hard palate. A case of sialadenoma papilliferum occurring in the parotid gland of a 49-year-old man is presented; only one such case has been previously described.
Spiral prominence epithelium
Authors: Sim D. W. 
Published: November 2007

AbstractRecent studies have shown neuroendocrine-type cells in human spiral prominence epithelium. A light microscopic and ultrastructural study was made on the guinea pig spiral prominence epithelium to try and identify neuroendocrine cells. The study showed that such cells were not present in the guinea pig spiral prominence epithelium. The spiral prominence epithelium was characterized by uniformity of cellular staining with Toluidine blue and the ultrastructural appearance. The morphology of the spiral prominence epithelium was similar to that previously described. The absence of neuroendocrine cells in spiral prominence epithelium in the guinea pig is discussed in relation to species differences.
Pneumatic otoscopy: Study of inter-observer variability
Authors: Mains B. T. , Toner J. G. 
Published: November 2007

AbstractThe degree of inter-observer variability in the results of pneumatic otoscopy, used to predict the presence or absence of middle ear effusion was assessed. A group of 114 patients with 209 suitable ears had pneumatic otoscopy using a Seigle's speculum performed independently by two observers. The results were compared to the findings at myringotomy, on the basis that mobility of the tympanic membrane was indicative of a dry middle ear. The observers agreed in 187 ears, a concordance rate of 91 per cent, and in 174 of these (93 per cent) the observers' prediction of middle ear state was correct. The overall predictive accuracy of observer A was 89 per cent and of observer B 84 per cent, this difference is not statistically significant, p> 0.05.
Treatment of auricular haematoma by silicone rubber splints
Authors: Nahl S. S. , Kent S. E. , Curry A. R. 
Published: November 2007

AbstractA modification of existing techniques for the treatment of auricular haematoma is described. This method employs incision, drainage and the application of silicone rubber splints (SilasticR). Existing methods of treatment are reviewed and discussed. A retrospective review of 16 cases using this technique showed a satisfactory cosmetic result in all cases.
Role and results of cortical mastoidectomy and endolymphatic sac surgery in Menière's disease
Authors: Kerr A. G. , Toner J. G. , McKee G. J. , Smyth G. D. L. 
Published: November 2007

AbstractIt is almost impossible to establish the natural history of Menière's disease and, by the same token, it is difficult to confirm the efficacy of endolymphatic sac surgery. The authors doubt the logic of sac operations. Only two controlled trials of sac surgery have been found and both cast doubt upon its value. There do not appear to be any controlled trials indicating that it works.In 14 cases of incapacitating Menière's disease, where vestibular nerve section was indicated, cortical mastoidectomy was offered and accepted in the expectation that two-thirds might be spared the more major procedure. In the event, the vertigo was controlled in eight out of 14 (57 per cent), the remaining six (43 per cent) requiring more major surgery.A surgical model illustrates that, of themselves, these results are essentially meaningless in assessing the efficacy of cortical mastoidectomy in Menière's disease. Until all cases in a community are considered and followed-up, we shall be in doubt about the value of sac surgery and most other treatments of Menière's disease.
Pilonidal sinus of the nose
Authors: Paulose K. O. , Khalifa S. Al , Raj S. Sunder , Saeed T. 
Published: November 2007

AbstractWe report an unusual case of a pilonidal sinus appearing on the nose. From the clinical and pathological findings, we find it difficult to believe that it is an acquired condition. En bloc excision by an external rhinoplasty approach was performed with no evidence of any recurrence.
Radio-opacity of fishbones
Authors: Ell S. R. 
Published: November 2007

AbstractBones are the largest group of foreign bodies found in the air and food passages. Fishbones which lodge in the tonsil can be easily seen and removed relatively easily. Those lodging in the pyriform fossa are well localized by the patient and can usually be seen on mirror examination.It would be useful to know which types of fishbones are radio-opaque and therefore likely to be shown by radiographs when mirror examination is difficult or fails to reveal a foreign body. Therefore a study was undertaken to ascertain the radio-opacity of the bones of ten different species of fish eaten in the British Isles.
St Cadoc and the healing of the deaf
Authors: Stephens S. D. G. 
Published: November 2007

AbstractThis manuscript traces the traditions of the healing of the deaf associated with St Cadoc. While Saint Cadoc was Welsh, the traditions associated with him are found in Brittany. It seems likely that they originated there as pre-Christian healing traditions which were subsequently incorporated into those associated with the Church. The centre of these traditions was (and is) St Cado in the South of Brittany, near Carnac.
Surgical treatment of glossopharyngeal neuralgia via the pharyngeal approach
Authors: Mairs A. P. , Stewart T. J. 
Published: November 2007

AbstractIdiopathic glossopharyngeal neuralgia is an uncommon disorder which often fails to respond to medical treatment. Surgical treatment most commonly consists of intracranial section of the glossopharyngeal nerve and upper vagal rootlets. We present three cases treated by the much simpler pharyngeal approach and argue that in appropriately selected patients this approach should receive more serious consideration.
Effect of nasogastric tubes on Eustachian tube function
Authors: Wake M. , McCullough D. E. , Binnington J. D. 
Published: November 2007

AbstractThe Eustachian tube acts as pressure equalizing tube between the nasopharynx and the middle ear. It also functions as a conduit for removal of secretions from the middle ear and mastoid air cell system into the post nasal space. Eustachian tube function may be assessed objectively using tympanometric measurements. (Brooks, 1968, Lutman, 1987).The post-operative use of nasogastric Ryles tubes is associated with reduced peak middle ear pressure (mmH2O) and reduced peak compliance volumes (ml) as assessed by tympanometry. In addition changes in the appearance of the tympanic membrane may occur with the protracted use of Ryles tubes. This phenomenon is a transient one.Nasogastric tube-induced Eustachian tube dysfunction is a previously unreported entity.