bluuebunny/crossref_metadata_2025_split huggingface dataset:
In silico approach through molecular docking and study ADME on imine derivative compounds as a potential antibacterial agent against Staphylococcus aureus
Authors: Frimayanti Neni , Nasution Musyirna Rahmah , Syah Aidil Fitrah 
Published: April 2024

Background: Antibiotics are drugs or compounds that inhibit or kill bacteria. Most natural and synthetic pharmacophores have been reported to be antimicrobial agents. One of these is an imine compound. Compounds containing imine groups exhibit various pharmacological activities, including antibacterial, antifungal, anti-HIV, anti-cancer, anti-inflammatory, antimalarial, and antituberculosis activities.
Objective: This study aimed to determine the potential of four imine-derived compounds as antibacterial agents using molecular docking.
Method: The molecular docking environment (MOE) 2022.0901 software package was used to perform molecular docking. Determination of the physicochemical and pharmacokinetic properties of the four imine-derivative compounds was performed online via the website www.swissadme.
Results: Based on the docking results, compound 1 has great potential as an antibacterial agent because its binding orientation was similar to that of the positive control. In addition, based on the Absorption, Distribution, Metabolism, and excretion (ADME) study, compound 1 was shown to be suitable for Lipinski's rule of five (RO5).
Conclusion: It can be concluded that compound 1 is easily absorbed, has good permeability, and can be used as a promising agent against Staphylococcus aureus.
Pengaruh Media Berbeda Terhadap Produksi Ulat Kandang (Alphitobius diaperinus) Sebagai Pakan Sumber Protein Ternak Unggas
Authors: Amran Muhammad , Haryadi Haryadi , Trisna A. 
Published: April 2024

Penelitian ini bertujuan untuk mengetahui pengaruh dari media berbeda terhadap produksi ulat kandang (Alphitobius diaperinus). Ulat kandang adalah ulat yang dapat digunakan sebagai pakan ternak unggas, ulat ini pada umumnya digunakan sebagai pakan burung kicau, akan tetapi ulat ini juga dapat dijadikan pakan ternak unggas sebagai sumber protein dalam pakan. Penelitian ini menggunakan metode eksperimental Rancangan Acak Lengkap (RAL) dengan 3 perlakuan dan 3 ulangan. Perlakuan adalah perbedaan media pertumbuhan ulat kandang yang digunakan, yaitu A : konsentrat, B : ampas tahu kering dan C : Dedak. Peubah yang diamati adalah produksi ulat kandang berat segar (g), panjang (cm) dan densitas populasi (ekor/cm3). Hasil penelitian menunjukan bahwa perbedaan media tumbuh pada ulat kandang memberi kan pengaruh nyata (P<0,05) terhadap berat segar (g), panjang (cm) dan densitas populasi (ekor/cm3). Kesimpulan dari penelitian ini adalah media tumbuh konsentrat dan ampas tahu kering memberikan hasil yang terbaik, dengan produksi berat segar 23,5 mg dan 22,3 mg, panjang 1,1 cm dan 1,0 cm, dan densitas populasi 1,83 ekor/cm3 dan 1,62 ekor/cm3.
DESIGN AND AESTHETICS IN TERENANG : A STUDY OF TRADITIONAL PAHANG POTTERY
Authors: Harun Zahirah , Abdul Hadi Hamidi , Ismail Issarezal , Ayob Salwa 
Published: April 2024

This study examines the interplay between design, aesthetic considerations, and the concept of beauty in the context of Terenang pottery, a traditional form of pottery originating from Pahang, Malaysia. Terenang pottery holds cultural significance and embodies the artistic traditions of the region. The research aims to explore how design principles and aesthetic choices contribute to the visual appeal and perceived beauty of terenang . Through a qualitative analysis encompassing visual examination, expert interviews, and literature review, this study investigates the design elements, motifs, material selection, and color palettes employed in terenang pottery. It explores how these elements are informed by cultural influences and artistic intentions to create objects that are both functional and aesthetically pleasing. By examining the concept of beauty within the context of Terenang pottery, this research provides insights into the cultural significance and artistic value of this traditional craft. The findings contribute to a deeper understanding of the intricate relationship between design, aesthetics, and the concept of beauty, shedding light on how these elements converge in the creation of visually appealing and culturally rich pottery.

Kehilangan beberapa industri tembikar tradisional di pelbagai kawasan di Malaysia, seperti di Alor Merah, Pulau Pinang, Bukit Gantang, Lenggong, dan Krian di Perak, menimbulkan kebimbangan mengenai kepupusan potensi perusahaan tembikar tradisional Melayu di Malaysia. Kebimbangan terhadap nasib serupa bagi perusahaan tembikar tradisional di Kampung Pasir Durian, Kuala Tembeling, Pahang, menekankan keperhatinan segera untuk menangani isu ini. Kajian ini memberi fokus kepada aspek formalistik dan konsep keindahan dalam tembikar terenang, dengan meneliti secara khusus reka bentuk, elemen dalam reka bentuk, teknik dan bahan, serta pemilihan motif. Kajian ini bertujuan merakam dan mendokumentasikan serta menganalisis aspek di atas menggunakan kaedah kualitatif, termasuk penyelidikan lapangan, arkib muzium, analisis visual, temu bual dengan artisan , dan kajian literatur. Dapatan kajian menyumbang kepada pemahaman yang lebih mendalam tentang reka bentuk, estetika, serta konsep keindahan dalam Islam. Kajian ini menerangkan kaedah elemen-elemen ini berhubungkait dalam penciptaan seni Melayu yang menarik secara visual dan memberikan wawasan berharga dalam pemeliharaan tembikar Melayu tradisional. Secara khusus, motif Terenang mengambil inspirasi dari sumber semulajadi terutamanya unsur flora dan fauna. Rekabentuk terenang menonjol kehalusan artistik dan pemilihan motif yang disusun secara hierarki yang memberikan keseimbangan kepada reka bentuk keseluruhan tembikar. Kajian ini berfungsi sebagai pendokumentasin menyeluruh mengenai tembikar terenang dan turut menyumbang kepada pemeliharaan budaya dan kehalusan kerja tangan tembikar tradisional di Malaysia.
Penerapan Prinsip Paradigma Good Governance dalam Implementasi Program Puspaga Balai RW: Studi Kasus Kelurahan Banyu Urip, Kecamatan Sawahan Kota Surabaya
Authors: Muhammad Faza Zakiy Makarim  , Indira Arundinasari  
Published: April 2024

Domestic violence or (KDRT), is a phenomenon of social problems within the family sphere that is rife in Indonesia, especially in big cities such as Surabaya as a result of economic problems, overcrowding and other problems. Responding to this problem, the Surabaya City Government initiated a Family Learning Center (Puspaga) program which was inaugurated in 2017. One of the areas that held the Puspaga program was RW 3 Banyu Urip Village, Sawahan District, Surabaya City. This study aims to reveal the principles of good governance contained in the implementation of Puspaga program policies in RW 3. Policy implementation analysis uses Edward III's policy implementation model which consists of four aspects, namely communication, resources, disposition, and bureaucratic structure. The research uses qualitative approaches and descriptive methods in the elaboration of research data. Research data collection techniques were carried out on secondary data in the form of literature studies, and on primary data using in-depth observation methods and closed interviews. The data analysis technique uses the Miles and Huberman analysis model. The research suggests that the Puspaga policy implementation program has run well and meets six principles in good governance, namely the principles of professionalism, accountability, transparency, excellent service, democracy and participation, efficiency and effectiveness, rule of law, while in the principle of transparency no data on budget resources was found due to limited researchers in finding informants.
An Assessment of Metal-Organic Frameworks and Activated Carbon Solutions for Sustainable Hydrogen Gas Storage
Authors: Mathew Anoushka , Chakraborty Anutosh , Ng Mai Sheng 
Published: April 2024

The pursuit of sustainable energy sources has elevated hydrogen gas as a potential carbon-neutral fuel with high energy content. However, efficient storage and transportation of hydrogen pose considerable challenges. To address these issues, the utilisation of metal-organic frameworks (MOFs) and activated carbon (AC) for hydrogen storage through adsorption has gained substantial attention. This research article offers a comprehensive assessment of hydrogen storage using these materials.
The adsorption mechanism, fundamental to hydrogen storage in MOFs, involves hydrogen molecules adhering to the MOF framework's surface and pores via intermolecular forces. MOFs, comprising metal nodes and organic linkers, present high surface area-to-volume ratios and customizable adsorption properties, making them appealing for gas storage. AC, an amorphous porous carbon form, also displays favourable traits for gas storage.
A State-of-the-Art Review on Image Synthesis with Generative Adversarial Networks
Authors: Sistla Sai Mani Krishna , Jangoan Suhas , Mohamed Ikram Ahamed 
Published: April 2024

Purpose: The remarkable performance of Generative Adversarial Networks (GANs) in various applications has made them a popular subject in computer vision research, and they have also shown remarkable success in picture synthesis tasks.
Materials and Methods: Image processing, synthesis, generation, semantic editing, translation, super-resolution, inpainting, and cartoon creation are all areas covered in this article's presentation of the most recent GAN research. To demonstrate how they have improved the result, they analyze the methods used by these applications and describe them.
Findings: Insights into GAN research and a presentation of GAN-based applications in diverse contexts are the goals of this paper (Anon, 2022).
Implications to Theory, Practice and Policy: Following this, we will go over some of the difficulties encountered by GANs and provide solutions to these issues. We also discuss potential future areas of study for GANs, including video creation, 3D face reconstruction, and facial animation synthesis.
Bleeding Per Rectum: A Retrospective Study of 120 Cases
Authors: AL-Ubaide Amer Fakhree , M. Al-Ani Raid 
Published: April 2024

Background: Lower gastrointestinal bleeding is one of the common problems seen worldwide, could be serious and occur at any age. Several studies conducted all over the world verified that there were variations in frequencies of etiologies of bleeding per rectum in their population, however, in the Middle East and Asia, the etiology of rectal bleeding differs from the West.
Objectives: To assess the causes of bleeding per rectum and to find if there is an association between rectal bleeding and various variables.
Subjects and methods: This was a retrospective cross-sectional study of 120 patients with bleeding per rectum for one year were studied in Al Ramadi Teaching Hospital, Ramadi City, Iraq. The patients underwent a full history and thorough physical examination. In all cases, initial digital rectal examination and proctoscopy were performed. Patients presented with a noticeable diagnosis of massive bleeding from the rectum were not included in our study.
Results: There were 84 males (64%) with male to female ratio of 2.33: 1. The median age of patients was 38 years (age ranged from 15-81 years). The main age group was ≤ 50 years (n = 95, 79.2%). The hemorrhoid was the most common cause of rectal bleeding (n = 95, 79.2%). The second cause was anal fissure which was found in 26 cases (21.65 %). Colorectal carcinoma was seen in 14 patients (11.67%), and most of them (n = 13) were above 50 years of age. There was no significant association between the rectal bleeding causes and the gender. However, there were highly significant differences between the causes and the age and bowel habits of the patients (P-value = 0.0001).
Conclusion: Hemorrhoids were the most prevalent cause of rectal bleeding. The patient's age and bowel habit might be determined the cause of bleeding per rectum.
DEGREE OF ACTIVATION OF NATURAL MECHANISMS OF HUMORAL AND CELLULAR DEFENSE BY BEE PRODUCTS IN BIRDS CANDIDAMYCOSIS
Authors: Маннапова Р.Т. , Свистунов Д.В. , Шайхулов Р.Р. 
Published: April 2024

Заболеваемость кандидамикозами пищеварительного тракта птиц регистрируется нечасто. Они возникают неожиданно, но летальность у молодняка достигает 95–100 %. Целью работы явилось изучить степень формирования и становления под влиянием биологически активных продуктов пчеловодства, характер восстановления на фоне кандидамикозов пищеварительного тракта (КПТ) птиц механизмов естественной иммунной защиты. Объектом исследования служили перепела мясной японской породы с 10- до 90-суточного возраста. Применение экстрактов восковой моли, трутневого гомогената пчел и прополиса (ЭВМ, ЭТГ и ЭП) способствовало повышению генетически заложенных потенциальных возможностей естественного гуморального и клеточного звена иммунитета здоровых перепелов и на фоне развития КПТ. Установлено повышение лизоцимной активности сыворотки крови под влиянием ЭВМ, ЭТГ и ЭП максимально, в пределах физиологических величин, у здоровых перепелов в 1,65; 3,44 и 2,13 раза, у больных КПТ – в 3,44; 5,38 и 4,93 раза; активизация бактерицидной активности сыворотки крови у здоровых птиц – в 1,40; 1,98 и 1,92 раза, у больных КПТ – в 2,18; 2,84 и 2,28 раза; повышение фагоцитарной активности альвеолярных макрофагов у здоровых перепелов – в 1,23; 1,38 и 1,31 раза, у больных КПТ – в 1,85; 2,67 и 1,88 раза. Более выраженные иммуностимулирующие свойства проявляет экстракт трутневого гомогената, затем прополиса, и незначительно уступает им экстракт восковой моли.
The incidence of candidamycosis of the avian digestive tract (CDT) is infrequent. They occur unexpectedly, but the mortality rate in young animals reaches up to 95–100 %. The aim of the work was to study the degree of formation and development of natural immune defense mechanisms under the influence of biologically active bee products and the nature of restoration of the birds digestive tract during the candidamycosis. The object of the study was Japanese meat quails from 10 to 90 days of age. The application of extracts of wax moth, bee drone homogenate and propolis contributed to an increase in the activity of the genetic capabilities of the natural humoral and cellular of immunity in healthy quails and during CDT. An increase in the lysozyme activity of blood serum under the influence of extracts of wax moth, bee drone homogenate and propolis was found to be maximum, within the limits of physiological values, in healthy quails by 1.65; 3.44 and 2.13 times, in sick birds with CDT – 3.44; 5.38 and 4.93 times. The activation of bactericidal activity of blood serum increased in healthy birds – by 1.40; 1.98 and 1.92 times, in sick birds with CDT – 2.18; 2.84 and 2.28 times; phagocytic activity of alveolar macrophages increased in healthy quails by 1.23; 1.38 and 1.31 times, in sick birds with CDT – 1.85; 2.67 and 1.88 times. The extract of bee drone homogenate has more significant immune-stimulating properties, followed by propolis, and the extract of wax moth is not significantly inferior to them.
Assessing Student Leaders’ Leadership Styles and Conflict Management
Authors: Ulanday Ma Leah , Samiento Lemellu Nida L , Santiago Cereneo jr. S , Centerno Zarah Jane R 
Published: April 2024

Student leadership gives students the training they need to engage themselves in school-related tasks or concepts, objectives, and aspirations beneficially and constructively. It teaches them how and when to plan an event, manage their schedule, improve their speaking abilities, and lead students. To achieve a target, leadership is a flexible process that calls for collaboration with others in both academic and professional lives. For individuals who are expanding their professional competencies, gaining leadership skills is essential. To enable students to learn their attributes and better prepare them for their careers, leadership qualities and skills should be measured. This study examined the profile in terms of age and sex, leadership styles, and conflict management of student leaders in a state university. A descriptive-correlation research design was employed in the study with undergraduate student leaders of their respective department organizations who enrolled in different courses. (N=70). Results show that majority of student leaders age is between 18- 21 and are dominated by male student leaders. It can also be gleaned that the majority of student leaders possess a democratic leadership style. Democratic leadership approaches have provided leaders the capability of making wise decisions, collaborating with others, and asking pertinent questions to people to handle certain issues. In terms of conflict management, the number one conflict management strategy used by the leaders is accommodating strategy Moreover, there is no significant relationship between the leadership style of student leaders and conflict management. Regardless of the leadership style of student leaders, it is up to them how they will handle conflict management effectively. Student leaders set the tone for conflict management through their leadership styles.
Diseño, Construcción y Pruebas de una Estación Terrena de Bajo Costo para CubeSat con Tecnología IoT-LoRa
Authors: Flores Cadena Gary Fernando , Lupera Morillo Pablo Aníbal , Mena Darwin Antonio , Benalcazar Rojas David , Llumiquinga Loya Henry Paul , Sandobalin Guaman Santiago , Lopez Izurieta Ericson Daniel 
Published: April 2024

En esta investigación se presenta el diseño y construcción de una estación terrena de bajo costo, compuestas por una antena Yagi, Amplificador de bajo ruido (LNA) y un nodo receptor LoRa que permite recepción de señales de CubeSats basadas en tecnología LoRa, para lo cual se emplearon conceptos de diseño general de antenas y amplificadores electrónicos y se comprobó el diseño mediante pruebas de laboratorio de características eléctricas, radiación de señal y respuesta en frecuencia con lo que se pudo recibir datos de telemetría de los satélites CubeSat LoRa.
PARENTING BEDA GENERASI: POLA ASUH ANAK DALAM PEMBELAJARAN HOLISTIK PADA ZAMAN MILENIAL
Authors: Woen Victoria 
Published: April 2024

Abstract: Child abuse has occurred across borders: brawls, theft, immorality, drugs, pornography, smoking, and the like. The purpose of this newsletter is to study parenting patterns from various generations, the characteristics and functions of their own circle of relatives, and techniques for holistic parenting to be recognized in the millennial era. This study uses a literature study with the results: (1) Generational differences in parenting because generations continue to move so that generational modifications have very large variations in parenting patterns within their own relatives. Now the Alpha era (Z era) born with this generation is growing rapidly. (2) The kinship circle itself is a collection unit in which there may be the presence of different parents, children, and relatives, and have emotional ties and interrelated experiences. (4) Child Parenting Patterns in Holistic Learning in Various Generations of Parenting: Families know parenting, Christ middleÂ noseÂ to parent, the person knows to parent, ability knows parenting, and cyber intelligent know to parent.
External Debts as Panacea to Economic Growth Challenges in Selected Eastern African countries: An Application of the Autoregressive Distributed Lag Model
Authors: Tile Augustino , Utouh Harold M.L. , Sesabo Jennifer Kasanda 
Published: April 2024

Foreign aid has significantly influenced medium- and long-term development initiatives in Eastern African countries. Project aid and non-project aid are the two main categories that describe foreign economic assistance (loans, credits, and grants). The primary aim of foreign aid has been to supplement the internal resources needed to quicken the economic development of the nations in Eastern Africa. This study investigated the influence of external debt on the economic growth of Eastern African countries (Kenya, Uganda, Rwanda, Burundi, and Tanzania) using the autoregressive distributive lag mode and panel data (1970–2020). The findings revealed that external debt had a significant adverse effect on economic growth. In Burundi, an increase in external debt reduces GDP by 5% in the short run, while in the long run, it reduces GDP by 19%; in Tanzania, it decreases GDP by 22%; and in Kenya, it reduces the GDP by 13%. Conversely, the findings indicated that the increased level of external debt positively influenced Uganda's GDP (0.03%) but was not statistically significant. Therefore, it is recommended that Eastern African countries source their income, apart from more external concessional debt, through bilateral or multilateral arrangements to plug into their budget deficits. Also, it is recommended that East African governments develop their external debt initiatives that offer further profitable investment opportunities to repay their foreign debt gradually. Moreover, strategies in the East African countries must be geared towards strengthening revenue mobilization to provide avenues to balance their external debts. For instance, improving the informal sector in these countries is a viable base for increasing revenue through taxes.
The effect of bio-organic fertilizers the productivity of potatoes and vegetable root crops in the conditions of the south-east of Kazakhstan
Authors: Budanov N. U. , Аitbayev Т. Е. , Barlykova N. A. 
Published: April 2024

Organic vegetables and potatoes are not produced in Kazakhstan. In this regard, the development of organic agricultural technologies is very important. Mineral fertilizers cannot be used in organic production. There are difficulties in preserving and increasing soil fertility, providing vegetables with all the necessary elements of nutrition. Therefore, the role of organic fertilizers and biological stimulators increases in soil and plant formation. Organic fertilizers are an important factor in preserving and increasing soil fertility, increasing yields, and improving quality, including the ecological purity of products, potatoes, and vegetables. The influence of local organic fertilizers, a new bio-organic fertilizer Baraebong Organic Fertilizer (Republic of Korea), and biological products on the nutritional regime of the soil and the productivity of potatoes and root crops (carrots and beets) was studied on the dark chestnut soil of the foothill zone of the south-east of Kazakhstan. Scientific research was carried out at the experimental station of the Regional branch "Kainar" LLP "Kazakh Scientific Research Institute of Fruit and Vegetable Growing". The research uses “The Methodology of Agrochemical Research”, “The Methodology of Experimental Work in Vegetable Growing and Melon Growing”, ‘The Methodology of Field Experience in Vegetable Growing”, and the methodological recommendations "Transition from Traditional to Bioorganic Farming in the Republic of Belarus". The positive effect of different types of bioorganic fertilizers on the nutritional regime of the soil was established such as the content of mobile forms of nitrogen, phosphorus, and potassium increased in it. The yield of potatoes from the introduction of bio-organic fertilizers into the soil increased by 17.4-87.5 %, carrots by 12.8-38.3 %, and beets by 14.0-46.2 %. Bio-organic fertilizers did not adversely affect the quality of potatoes in terms of nitrate content. The level of nitrates in tubers was at the level of 65-215 mg/kg with a MPC of 250 mg/kg. Carrots grown with the use of various bio-organic fertilizers contained 47-136 mg/kg of nitrates at MPC 400 mg/kg, and beet contained 132-429 mg/kg of nitrates at MPC 1400 mg/kg.