bluuebunny/crossref_metadata_2025_split huggingface dataset:
Plasma tissue factor pathway inhibitor levels in coronavirus disease 2019 patients: a systematic review and meta-analysis
Authors: Hassani Saeed , Sayyadi Mohammad , Almasi-Hashiani Amir 
Published: April 2024

Studies have suggested a relationship between tissue factor pathway inhibitor (TFPI) and coronavirus disease 2019 (COVID-19) severity. However, there is inconsistency in the findings of the studies. To enhance comprehension of this relationship, a meta-analysis was conducted. PubMed, Web of Science, and Scopus databases were searched to identify eligible studies. The mean difference was employed as effect measures and the standardized mean difference (SMD) and the 95% confidence interval (CI) were utilized as a summary statistic. Heterogeneity was assessed through the application of the chi-square test and the I
2 statistic. The included studies’ quality and risk of bias were assessed using the Newcastle–Ottawa assessment scale, adapted for case–control studies. A total of six studies were included with 684 cases and healthy controls (180 healthy controls and 504 COVID-19 patients with different severity, 76 mild, 292 moderate, and 136 severe). The analysis revealed a significant increase in the TFPI level in COVID-19 patients with moderate severity compared with healthy controls (SMD = 0.95 ng/ml, 95% confidence interval (CI) 0.27, 1.63 ng/ml; I
2: 87.2%). The increased TFPI level in mild and moderate COVID-19 was not significant, SMD = 0.68 ng/ml, 95% CI −0.64 to 2.0 ng/ml; I
2 92.9% and SMD = 0.62 ng/ml, 95% CI −0.62 to 1.86 ng/ml; I
2 91.5%, respectively. In addition, most studies indicate an association of the increased TFPI concentrations with increased markers of inflammation, endothelial damage, and hypercoagulation. Considering the anticoagulant and anti-inflammatory roles of TFPI, its increase seems to be aimed at modulating COVID-19-induced hyper-inflammation and hyper-coagulation state.

Systematic review registration
PROSPERO CRD42023437353
Effectiveness of Cognitive Behavioral Therapy on Fear of Cancer Recurrence in Breast Cancer
Authors: Wei Fangxin , Yang Xin , He Ruiyao , Hu Ziqi , Wang Yu 
Published: April 2024

Background
Fear of cancer recurrence is one of the psychological distresses that seriously affects the quality of life of breast cancer patients. However, the evidence for cognitive behavioral therapy on fear of cancer recurrence in breast cancer is limited.

Objective
The aim of this study was to evaluate the effectiveness of cognitive behavioral therapy in reducing breast cancer patients’ fear of cancer recurrence.

Methods
Seven databases were searched for randomized controlled studies on cognitive behavioral therapy for fear of cancer recurrence in cancer patients from the inception of the database to April 30, 2023, with no language restrictions. Meta-analysis was performed using Stata MP 17. The Cochrane Risk of Bias Tool version 2 was used to assess the quality of the included studies. The quality of evidence was assessed using the Grading of Recommendations, Assessment, Development and Evaluation method.

Results
This review includes a total of 13 randomized controlled trials with 1447 breast cancer patients and survivors. When compared with controls, meta-analysis revealed that cognitive behavioral therapy significantly reduced the fear of cancer recurrence (g = −0.44; 95% confidence interval, −0.75 to −0.13; P < .001), whereas subgroup analysis revealed that only mindfulness-based cognitive therapy was significant. The overall risk of bias was high. The Grading of Recommendations, Assessment, Development and Evaluation assessment showed a low overall quality of evidence.

Conclusions
Cognitive behavioral therapy may be effective in reducing fear of cancer recurrence in breast cancer patients, and mindfulness-based cognitive therapy is particularly worthy of implementation.

Implications for Practice
Mindfulness-based cognitive therapy may be used as an additional strategy to help manage breast cancer patients’ fears of cancer recurrence.
Clinical Intricacies and Advances in Neuroendocrine Tumors: An Organ-Based Multidisciplinary Approach
Authors: Asmundo Luigi , Ambrosini Valentina , Anderson Mark A. , Fanti Stefano , Bradley William R. , Campana Davide , Mojtahed Amirkasra , Chung Ryan , Mcdermott Shaunagh , Digumarthy Subba , Ursprung Stephan , Nikolau Konstantin , Fintelmann Florian J. , Blake Michael , Fernandez-del Castillo Carlos , Qadan Motaz , Pandey Ankur , Clark Jeffrey W. , Catalano Onofrio A. 
Published: April 2024

Abstract
Neuroendocrine neoplasms (NENs) are rare neoplasms originating from neuroendocrine cells, with increasing incidence due to enhanced detection methods. These tumors display considerable heterogeneity, necessitating diverse management strategies based on factors like organ of origin and tumor size. This article provides a comprehensive overview of therapeutic approaches for NENs, emphasizing the role of imaging in treatment decisions. It categorizes tumors based on their locations: gastric, duodenal, pancreatic, small bowel, colonic, rectal, appendiceal, gallbladder, prostate, lung, gynecological, and others. The piece also elucidates the challenges in managing metastatic disease and controversies surrounding MEN1–neuroendocrine tumor management. The article underscores the significance of individualized treatment plans, underscoring the need for a multidisciplinary approach to ensure optimal patient outcomes.
Accurate determination of breed origin of alleles in a simulated smallholder crossbred dairy cattle population
Authors: Welderufael Berihu , Houaga Isidore , Gaynor Chris R , Gorjanc Gregor , Hickey John M 
Published: April 2024

AbstractBackgroundAccurate assignment of breed origin of alleles at a heterozygote locus may help to introduce a resilient or adaptive haplotype in crossbreeding. In this study, we developed and tested a method to assign breed of origin for individual alleles in crossbred dairy cattle. After generations of mating within and between local breeds as well as the importation of exotic bulls, five rounds of selected crossbred cows were simulated to mimic a dairy breeding programme in the low- and middle-income countries (LMICs). In each round of selection, the alleles of those crossbred animals were phased and assigned to their breed of origin (being either local or exotic).ResultsAcross all core lengths and modes of phasing (with offset or no), the average percentage of alleles correctly assigned a breed origin was 95.76%, with only 1.39% incorrectly assigned and 2.85% missing or unassigned. On consensus, the average percentage of alleles correctly assigned a breed origin was 93.21%, with only 0.46% incorrectly assigned and 6.33% missing or unassigned. This high proportion of alleles correctly assigned a breed origin resulted in a high core-based mean accuracy of 0.99 and a very high consensus-based mean accuracy of 1.00. The algorithm’s assignment yield and accuracy were affected by the choice of threshold levels for the best match of assignments. The threshold level had the opposite effect on assignment yield and assignment accuracy. A less stringent threshold generated higher assignment yields and lower assignment accuracy.ConclusionsWe developed an algorithm that accurately assigns a breed origin to alleles of crossbred animals designed to represent breeding programmes in the LMICs. The developed algorithm is straightforward in its application and does not require prior knowledge of pedigree, which makes it more relevant and applicable in LMICs breeding programmes.
Hepatitis E Virus-induced antiviral response by plasmacytoid dendritic cells is modulated by the ORF2 protein
Authors: Joshi Garima , Décembre Elodie , Brocard Jacques , Montpellier Claire , Ferrié Martin , Allatif Omran , Mehnert Ann-Kathrin , Pons Johann , Galiana Delphine , Dao Thi Viet Loan , Jouvenet Nolwenn , Cocquerel Laurence , Dreux Marlène 
Published: April 2024

AbstractType I and III interferons (IFN-I/III) are critical to protect the host during viral infection. Previous studies have shown that IFN-mediated antiviral responses against hepatitis E virus (HEV) are suppressed and defeated by viral escape mechanisms at play in infected hepatocytes. Here, we studied the anti-HEV function of IFN secreted by plasmacytoid dendritic cells (pDCs), which are specialized producers of IFNs. We showed that pDCs co-cultured with HEV-replicating cells secreted IFN in a cell-to-cell contact-dependent manner. Pharmacological inhibitor and antibodies targeting contact proteins revealed that pDC response against HEV required the endosomal nucleic-acid sensor TLR7 and adhesion molecules, such as ICAM-I and αLβ2-integrin. IFNs secreted by pDCs reduced viral spread. Intriguingly, ORF2, the capsid protein of HEV, can be produced in various forms by the infected cells. During infection, a fraction of the intracellular ORF2 protein localizes into the nucleus while another ORF2 fraction packages viral genomes to produce infectious virions. In parallel, glycosylated forms of ORF2 are also massively secreted by infected cells. Using viral genome expressing ORF2 mutants, we showed that glycosylated ORF2 forms contribute to better recognition of infected cells by pDCs via regulation of contacts between infected cells and pDCs. ORF2 forms may thus modulate pDC-mediated anti-HEV response. Together, our results suggest that liver-resident pDCs, which exhibit comparable IFN-producing ability as blood-derived pDCs, may be essential to control HEV replication.
Topologically protected Casimir effect for lattice fermions
Authors: Beenakker C. W. J. 
Published: April 2024

The electromagnetic Casimir effect has a fermionic counterpart in topological insulators: Zero-point fluctuations of a massless Dirac fermion field mediate a force between magnetic scatterers. The Casimir force is insensitive to disorder that preserves the topological protection of an unpaired Dirac cone. The protection may be broken if the Dirac equation is discretized, and an exponential suppression of the Casimir effect will result if a gap opens at the Dirac point. Here, we show how this lattice artifact may be avoided, by applying a recently developed local discretization of the Euclidean action that does not suffer from the fermion-doubling obstruction of local discretizations of the Hamiltonian.

Published by the American Physical Society
2024
Online harvesting of municipality websites into trusted digital repository
Authors: Luthuli Lungile Precious , Ngoepe Mpho 
Published: April 2024

Purpose
Municipalities, as the front lines of service delivery, use websites as one of the tools to communicate information to the public. While it is considered a record, many organisations, including municipalities, do not manage websites as such. This study aims to explore the archiving of websites as records in the municipalities of KwaZulu-Natal (KZN) Province in South Africa by using the web archiving life cycle model.

Design/methodology/approach
This study used a mixed-methods research with an explanatory design, with quantitative data collected first through content analysis of websites and qualitative data collected through interviews. Researchers used multilevel sampling, first quantitatively analysing all available websites of the municipalities (52) in KZN, and then qualitatively selecting only records managers, information managers, web administrators, communication managers and website managers or designers from municipalities because of their understanding and involvement with websites in some way.

Findings
This study established that some records on municipal websites are often in paper format in record-keeping systems, whereas others are born digital and are not captured in the systems. Municipalities lack a dedicated web online harvesting tool as well as an archiving policy or strategy to guide website archiving. Furthermore, municipalities placed a high reliance on service providers to keep their websites operational.

Research limitations/implications
It became clear during the interviews that most of the participants were unfamiliar with web archiving. As a result, only 12 of the 56 selected participants from the municipalities provided the required information in relation to the current study as others could not provide answers. Data for other participants were not analysed.

Originality/value
Due to a lack of infrastructure for ingesting digital records into archival custody, a framework for harvesting web content of value is proposed both internally in municipalities and externally to an archive repository.
Spatial and temporal diffusion of property prices and sales across British regions
Authors: Salov Anton 
Published: April 2024

Purpose
The purpose of this study is to reveal the dynamics of house prices and sales in spatial and temporal dimensions across British regions.

Design/methodology/approach
This paper incorporates two empirical approaches to describe the behaviour of property prices across British regions. The models are applied to two different data sets. The first empirical approach is to apply the price diffusion model proposed by Holly et al. (2011) to the UK house price index data set. The second empirical approach is to apply a bivariate global vector autoregression model without a time trend to house prices and transaction volumes retrieved from the nationwide building society.

Findings
Identifying shocks to London house prices in the GVAR model, based on the generalized impulse response functions framework, I find some heterogeneity in responses to house price changes; for example, South East England responds stronger than the remaining provincial regions. The main pattern detected in responses and characteristic for each region is the fairly rapid fading of the shock. The spatial-temporal diffusion model demonstrates the presence of a ripple effect: a shock emanating from London is dispersed contemporaneously and spatially to other regions, affecting prices in nondominant regions with a delay.

Originality/value
The main contribution of this work is the betterment in understanding how house price changes move across regions and time within a UK context.
Corporate board, assurance and sustainability reporting practices: a focus on selected African countries
Authors: Erin Olayinka Adedayo , Ackers Barry 
Published: April 2024

Purpose
In recent times, stakeholders have called on corporate organizations especially those charged with governance to embrace full disclosure on non-financial issues, especially sustainability reporting. Based on this premise, this study aims to examine the influence of corporate board and assurance on sustainability reporting practices (SRP) of selected 80 firms from 8 countries in sub-Saharan Africa.

Design/methodology/approach
To measure the corporate board, the authors use both board variables and audit committee variables. Also, the authors adapted the sustainability score model as used by previous authors in the field of sustainability disclosure to measure SRPs. The analysis was done using both ordered logistic regression and probit regression models.

Findings
The results show that the combination of board corporate and assurance has a positive and significant impact on the sustainability reporting practice of selected firms in sub-Saharan Africa.

Practical implications
The study places emphasis on the need for strong collaboration between the corporate board and external assurance in evaluating and enhancing the quality of sustainability disclosure.

Originality/value
The study bridged the gap in the literature in the area of corporate board, assurance and SRP of corporate firms which has received little attention within sub-Saharan Africa.
The effect of tax avoidance on earnings persistence: evidence from China
Authors: Xu Yan 
Published: April 2024

PurposeThe purpose of this paper is to investigate the relationship between tax avoidance and earnings persistence in the light of a developing economy, with the main focus on China.Design/methodology/approachIn the analysis, the author conducts a survey on the tax avoidance situation of Chinese listed companies from 2012 to 2020. Then, a multivariate regression analysis is performed in order to analyse the relationship between corporate tax avoidance and earnings persistence.FindingsThe findings of the present study show that tax avoidance has a significant positive effect on earnings persistence. However, when the degree of tax avoidance is high, the “risk effect” of tax avoidance exceeds the “value effect”, and tax avoidance will reduce the persistence of earnings. This conclusion is even more prominent when the company is non-state-owned. Further research shows the increase of institutional investors’ shareholding ratio can improve “value effect” of tax avoidance, lessen “risk effect” of tax avoidance, and positively affect the relationship between tax avoidance and earnings persistence.Practical implicationsThis study provides evidence for investors to understand the dual effect of tax avoidance on earnings persistence. The results may have implications for regulatory bodies. They can provide a better understanding of the corporate governance role of institutional investors in curbing opportunistic tax avoidance.Originality/valueThis study enriches the research on tax avoidance effects by analysing the impact of tax avoidance on earnings persistence. This study also compensates for the shortcomings of analysing earnings persistence mainly from the perspective of tax differences in the past, and promotes the study of the corporate governance effects of institutional investors under different levels of tax avoidance.
Leadership identity development, meaning-making and the intersection of marginalized social identities: a scoping review
Authors: Orsini Jonathan , Sunderman Hannah M. 
Published: April 2024

PurposeThe current paper is part of a larger scoping review project investigating the intersection of leader(ship) identity development and meaning-making. In this review, we analyzed 100 articles to determine the current extent of literature that covers the intersection of leader(ship) identity development, meaning-making and marginalized social identities.Design/methodology/approachA review of the extant literature is included, and a conceptual model is suggested for further exploration into this critical and under-researched domain.FindingsMore research is needed at the intersection of leadership identity development, meaning-making and marginalized social identities.Originality/valueAs this area of study has expanded, scholars have noted an absence of research on the effect of multiple social identities, especially marginalized identities, on meaning-making and leadership identity construction.
Research on decoupling control of single leg joints of hydraulic quadruped robot
Authors: Gao Bingwei , Zhao Hongjian , Han Wenlong , Xue Shilong 
Published: April 2024

Purpose
This study proposes a predictive neural network model reference decoupling control method for the coupling problem between the leg joints of hydraulic quadruped robots, and verifies its decoupling effect..

Design/methodology/approach
The machine–hydraulic cross-linking coupling is studied as the coupling behavior of the hydraulically driven quadruped robot, and the mechanical dynamics coupling force of the robot system is controlled as the disturbance force of the hydraulic system through the Jacobian matrix transformation. According to the principle of multivariable decoupling, a prediction-based neural network model reference decoupling control method is proposed; each module of the control algorithm is designed one by one, and the stability of the system is analyzed by the Lyapunov stability theorem.

Findings
The simulation and experimental research on the robot joint decoupling control method is carried out, and the prediction-based neural network model reference decoupling control method is compared with the decoupling control method without any decoupling control method. The results show that taking the coupling effect experiment between the hip joint and knee joint as an example, after using the predictive neural network model reference decoupling control method, the phase lag of the hip joint response line was reduced from 20.3° to 14.8°, the amplitude attenuation was reduced from 1.82% to 0.21%, the maximum error of the knee joint coupling line was reduced from 0.67 mm to 0.16 mm and the coupling effect between the hip joint and knee joint was reduced from 1.9% to 0.48%, achieving good decoupling.

Originality/value
The prediction-based neural network model reference decoupling control method proposed in this paper can use the neural network model to predict the next output of the system according to the input and output. Finally, the weights of the neural network are corrected online according to the predicted output and the given reference output, so that the optimization index of the neural network decoupling controller is extremely small, and the purpose of decoupling control is achieved.
Impact of concurrent medications on the outcome of immunotherapy in non‐small cell lung carcinoma
Authors: Yamada Jun , Fukui Takafumi , Yatani Atsuhiko , Mimura Chihiro , Fukuda Kiyoko , Hazama Daisuke , Katsurada Naoko , Nagano Tatsuya , Yamamoto Masatsugu , Tachihara Motoko 
Published: April 2024

AbstractBackgroundThere have been reports on the impact of concurrent drugs on the outcome of immunotherapy for non‐small cell lung carcinoma (NSCLC). However, the effect of some drugs, such as antibiotics and nonsteroidal anti‐inflammatory drugs (NSAIDs), has not been clarified in patients with NSCLC. In the present study, we aimed to assess the association between concurrent drugs and the outcomes of immune checkpoint inhibitors (ICIs) alone or in combination with chemotherapy for patients with advanced NSCLC.MethodsWe retrospectively assessed patients with advanced NSCLC who underwent ICI treatment between September 2017 and December 2021 at Kobe University Hospital. We evaluated the data regarding the use of antibiotics within 30 days before ICI initiation, as well as the use of proton pump inhibitors (PPIs) and NSAIDs during ICI initiation.ResultsA total of 127 patients were assessed, among whom 28 (22.0%) patients received antibiotics, 39 (30.7%) PPIs, and 36 (28.3%) NSAIDs. No significant differences were observed between the patients with and without antibiotic use. However, patients using NSAIDs had significantly worse objective response rates (ORR) and progression‐free survival (PFS) with ICI alone or in combination with chemotherapy compared to those who did not (ORR, 47.2% vs. 67.0%; p = 0.045. PFS, 6.3 months vs. 10.8 months; p = 0.02). Patients using PPIs demonstrated a worse ORR of ICI in combination with chemotherapy compared to those who did not (ORR, 45.2% vs. 72.6%; p = 0.013).ConclusionsThe unnecessary use of NSAIDs along with immunotherapy should be discouraged.