bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pushing Back
Authors: Costello Cathryn , Zirulia Stefano 
Published: February 2024

The CJEU has pending before it a crucial case on the criminalisation of seeking asylum and assistance to those seeking protection. At this critical juncture, this blog post highlights a sample of important decisions in which courts, giving effect to constitutional and international legal principles, set legal limits on this form of criminalisation. These cases reflect not only the appropriate legal limits, but also acknowledge the character of irregular migration and smuggling. Rather than framing individuals as dangerous illegal migrants and exploitative smugglers, they reassert the humanity of both those in search of refuge and opportunity, and those that assist them.
Hubungan Mutu Pelayanan Keperawatan Dengan Tingkat Kepuasan Pasien Rawat Inap Pada Masa Pandemi Covid 19 Di Ruang Mina Rumah Sakit Aisyiyah Pariaman Tahun 2021
Authors: Dora Mechi Silvia , Ramaita Ramaita 
Published: February 2024

Mutu pelayanan keperawatan merupakan suatu proses kegiatan yang dilakukan oleh profesi keperawatan dalam pemenuhan kebutuhan pasien. Salah satu indikator mutu pelayanan adalah kepuasan pasien. Penelitian ini bertujuan untuk mengetahui hubungan mutu pelayanan keperawatan dengan tingkat kepuasan pasien rawat inap di ruang mina rumah sakit aisyiyah pariaman tahun 2021. Desain penelitian termasuk dalam penelitian kuantitatif dengan jenis korelasi dengan pendekatan cross sectional. Penelitian ini dilaksanakan pada tanggal 19 juni s/d 22 juli 2021. Tempat penelitian di lakukan di Rumah Sakit Aisyiyah Pariaman di Ruang Mina. Jumlah sampel yang 36 orang dengan menggunakan teknik purposive sampling. Alat pengumpulan data dilakukan dengan menggunakan kuesioner dan analisa stastitik menggunakan uji Chi-square. Hasil analisa yang di dapat bahwa mutu pelayanan keperawatan di rumah sakit aisyiyah pariaman di kategori baik (55.6%), dengan tingkat kepuasan yaitu puas (63.9%). Hasil penelitian menunjukan adanya hubungan yang bermakna antara mutu pelayanan keperawatan (p value= 0.000<0.05) dengan tingkat kepuasan pasien rawat inap. Kesimpulan penelitian ini adanya hubungan yang bermakna antara Mutu Pelayanan Keperawatan Dengan Tingkat Kepuasan Pasien Rawat Inap Di Ruang Mina Rumah Sakit Aisyiyah Pariaman Tahun 2021. Diharapkan rumah sakit aisyiyah pariaman khususnya di ruang mina agar dapat mempertahankan mutu pelayanan keperawatan dan melakukan survei kepuasan pasien secara berkala dan berkesinambungan untuk mengevaluasi kinerja pelayanan keperawatan dan mutu pelayanan rawat inap.
Analisis Mikrobiologi Air Minum Isi Ulang Disekitar Kampus Iii Bung Hatta Padang Dengan Metoda Mpn (Most Probable Number)
Authors: Lestari Ratna 
Published: February 2024

Air merupakan kebutuhan dasar bagi setiap makhluk hidup. Air berfungsi sebagai pelarut senyawa-senyawa organik dan menstabilkan suhu tubuh, serta membantu berlangsungnya berbagai reaksi kimia pada tingkat seluler. Selain memberi manfaat yang menguntungkan, air juga dapat menimbulkan dampak buruk terhadap kesehatan apabila air yang digunakan tidak memenuhi persyaratan kesehatan. Beberapa penyakit berbahaya yang disebabkan karena mengkonsumsi air yang terkontaminasi diantaranya adalah diare, kolera, disentri, hepatitis A, thypoid dan polio. Dalam penyediaan air bersih siap minum, Depot Air Minum isi Ulang (DAMIU) harus memastikan kualitas airnya memenuhi standar persyaratan kesehatan yang berlaku. Menurut data yang diperoleh, cukup banyak DAMIU yang tidak memenuhi persyaratan tersebut. Tujuan penelitian ini adalah untuk melakukan pengujian kualitas air minum isi ulang di sekitar kampus III Bung Hatta sesuai parameter mikrobiologi dengan metoda MPN. Metoda MPN (Most Probable Number) terdiri dari uji penduga (presumptive test), uji penguat (confirmed test) dan uji pelengkap (completed test). Jenis penelitian ini adalah deskriptif kualitatif melalui uji laboratorium. Hasil penelitian menunjukkan bahwa dari empat sampel air minum isi ulang yang di uji (sampel 1,2 3 dan 4) semuanya menunjukkan hasil positif terkontaminasi bakteri Coliform dari golongan E. coli. Total bakteri Coliform tertinggi adalah pada sampel 4 yaitu 460 MPN/100ml dan terendah pada sampel 3 yaitu 64 MPN/100ml. Keempat sampel yang diuji tidak memenuhi persyaratan kualitas air minum yang ditetapkan oleh PERMENKES No.492 tahun 2010.
UTILIZAÇÃO DE TENÉBRIO MOLITOR COMO FONTE PROTEICA PARA A ALIMENTAÇÃO DE AVES.
Authors: Jenifer Alves Glória Leila , Teixeira de Diniz Gabriela , Pereira Campos Kenedy , Otávio Cabral Neto  , Carlos Silveira Gonçalves Antônio 
Published: February 2024

O aumento e demanda da população exige um reforço na produção dos alimentos necessários para dieta dos mesmos, para isso ocorrer, é necessário um cuidado diferenciado a essas fontes para que gerem produtividade, sem agredir o bem estar desses animais. Sendo assim, o trabalho de pesquisa tem como objetivo trazer uma alimentação com maior teor de proteína às aves, garantindo o ganho de peso rápido, e o tempo mínimo para o abate, enfatizando também a importância de uma nutrição proteica na dieta animal, pois a mesma representa uma parcela significativa dos custos com nutrientes. Foi utilizada uma abordagem de pesquisa exploratória, tendo levantamento em pesquisas de sites confiáveis e renomados como: Google Acadêmico, Periódicos Capes e Web off Science, compilando informações relacionadas aos principais resultados sobre a utilização da farinha de Tenébrio Molitor na alimentação de aves de corte. Nota-se a necessidade de fontes alternativas de proteína na alimentação animal devido ao aumento da população global e o impacto ambiental das fontes tradicionais de proteína como a soja e o milho. A inclusão de proteínas de insetos na alimentação animal pode ter efeitos ambientais positivos, como a redução das emissões de gases com efeito estufa e a deflorestação. Conclui-se que Tenébrio molitor é uma alternativa proteica promissora para alimentação desses animais devido ao seu alto valor nutricional, baixo impacto ambiental e custo-benefício. No entanto, são necessárias mais pesquisas e investimentos para desenvolver plenamente a produção dessa proteína e sua utilização na alimentação animal.
Palavras-chave: Tenebrio molitor, alimento alternativo, proteína, aves de corte
Impact of toll-like receptor 4 variations on nasopharyngeal carcinoma risk and survival in tunisian population
Authors: Ben Chaaben Arij , Ayadi Imen , Abaza Hejer , Baroudi Olfa , Douik Hayet , Harzallah Latifa , Bouassida Jihen , Bouckouaci Wahid , Guemira Fethi , Mankai Amani , Kharrat Maher , Tamouza Ryad 
Published: February 2024

Introduction: The Toll-like receptor 4 (TLR4), an important member of the host's innate immune response, is coded by a polymorphic gene. This polymorphism could be a predisposing factor for NasoPharyngeal Carcinoma (NPC).
Aim: To determine the association between TLR4 gene polymorphisms and the susceptibility to NPC in a cohort of Tunisian affected patients.
Methods: Genomic DNAs from 245 unrelated patients affected by undifferentiated carcinoma type (UCNT) and 264 unrelated healthy controls were genotyped for the five single nucleotides polymorphisms (SNPs) of TLR4 locus (4434 A>G (rs1927914),7263 G>C (rs10759932), 6134 A>G(rs4986790), 8851C>T (rs 4986791), 5272 T>C(rs11536889), +8469 T>C (rs11536891)) by Taqman® 5’-nuclease assay.
Results: Among all polymorphisms studied, only the rs4986790 G and rs4986791 T alleles were significantly more prevalent in patients’ group than controls (45% vs. 38%; p=0.03; pc=0.06) and increased the risk of the NPC (OR=1.3, 95% CI=1.01-1.69). Also, we found that the frequency of the rs4986790 AA and rs4986791 TT genotypes was significantly higher in controls than in patients (25.7% vs 37%; p=0.006, pc=0.02) and conferred a protector factor in NPC (OR= 0.59, 95% CI= 0.39-0.87). Further, based on the Kaplan-Meier survival curve we observed also the positive effect ofrs1927914 AA genotype on a prognostic of NPC (p=0.006; pc=0.01).
Conclusion: Our study demonstrated that impaired production of TLR4 seems to be a risk factor of NPC development but functional studies are needed to confirm these findings. As to rs1927914 AA appears to be a good biomarker for better survival in a patient with NPC.
Secuelas post-COVID 19 y su impacto en el estado funcional de los pacientes: experiencia en una Unidad de Medicina Familiar del Estado de México
Authors: Ortiz Vilchis Cristian Miguel , Avilés Sanchez María Emiliana 
Published: February 2024

Objetivo: Describir las secuelas funcionales en pacientes que presentaron algún tipo de secuela post COVID-19. Métodos: Estudio transversal, analítico y descriptivo. Se efectuó en la Unidad de Medicina Familiar No. 220 del Instituto Mexicano del Seguro Social en la ciudad de Toluca, Estado de México. Muestreo no probabilístico, fue obtenida una muestra de 117 pacientes; se realizó entre los meses de junio a diciembre del 2021. Fue aplicada la Escala Estatus Funcional Post-COVID-19 (PCFS). Estudio aprobado por el Comité de Ética e Investigación. Los datos obtenidos se analizaron mediante el paquete estadístico SPSS 26. Resultados: Grupo de edad más representativo: de 30-40 años (35.9%), mujeres (67.5%). Casados (59.8%). Educación secundaria (38.5%), bachillerato (36.8%). Empleados (76.1%). Reportaron hospitalización (33.3%). De acuerdo al grado de disfunción: moderada 35%, leve 28.2%, mínima 18.8% y severa 8.5%. Principales secuelas: fatiga (42.7%), alteraciones neurocognitivas (29.1%). El resultado de χ2 fue de 0.062 por lo que no existió significancia estadística de la asociación entre las dos variables principales. Conclusiones: No siempre la gravedad inicial de la COVID-19 predice secuelas que conlleven al paciente a modificar su estado funcional. Los médicos familiares deberían considerar factores individuales, educar a los pacientes sobre la variabilidad de secuelas, adoptar un enfoque multidisciplinario y seguimiento continuo.
Percepción de cambios en la Funcionalidad Familiar en pacientes con Diabetes Mellitus Tipo 2 posterior a una intervención educativa
Authors: Martínez Hernández Saida , Fernández Martínez Sergio Carlos , Palma Jiménez Imelda , Romero Santamaría Yury Montserrat , Meneses Lara José Eduardo 
Published: February 2024

Objetivo: Determinar la percepción de cambios en la Funcionalidad Familiar en pacientes con Diabetes Mellitus Tipo2 posterior a una Intervención Educativa. Métodos: Se realizó un estudio cuasi experimental, muestra de 298 participantes en la Unidad de Medicina Familiar, Número 22 de Teziutlán Puebla. Instituto Mexicano del Seguro Social. Se realizó una evaluación pre y post intervención utilizando el test FF-SIL para funcionalidad familiar (alfa de Cronbach de 0.931). Se analizó con estadística no paramétrica. Resultados: El 54.7% de las familias se clasificaron como “moderadamente funcionales” en la Pre-Intervención pasando a un porcentaje de 91.7% como familia “funcional” en la post-intervención. Conclusiones: Se demostró con una significancia estadística (p=0.000) que la Intervención Educativa modificó la percepción de la funcionalidad familiar de los pacientes con diabetes mellitus Tipo 2.
Reflexões sobre dois aspectos da formação médica a partir de experiências de estudantes de medicina
Authors: Smaniotto Raulik Brenda Gabriele , Freire Martins Martha , Monteiro Baptista da Silva Daniela , De Almeida Nogueira Montenegro Leonardo , De Almeida Nogueira Montenegro Ricardo , Ayres Rossini Guilherme 
Published: February 2024

A utilização de metáforas para representar a complexa situação em que o paciente crônico institucionalizado se encontra pode auxiliar na melhor tomada de decisões do médico que assiste esses pacientes. O presente artigo discorre, a partir dos relatos de duas experiências clínicas de estudantes de medicina com tais pacientes, sobre dois aspectos metafóricos importantes para a formação médica: 1) gut feelings – habilidade reconhecida que se aperfeiçoa com os anos de prática clínica, mas que é difícil de ser definida e 2) o médico como o “segundo prisma” -em analogia ao experimento óptico de Isaac Newton- na qual o médico faz o papel de segundo prisma que recebe todas as informações do paciente, familiares e da equipe multidisciplinar (luzes coloridas) e as transforma em um plano terapêutico que dê segurança para equipe, assistência e conforto para o paciente (com a convergência de todas as luzes coloridas em luz branca de volta ao paciente).
Enjeux et tensions associés à la scolarisation des élèves du secondaire issus des minorités visibles au Saguenay–Lac-Saint-Jean, au Québec
Authors: Amboulé-Abath Anastasie 
Published: February 2024

Cet article présente la manière dont les élèves au secondaire issus des minorités visibles, et fréquentant deux écoles du secondaire situées dans une région excentrée et à faible densité ethnoculturelle, décrivent leur expérience socioscolaire. Il s’intéresse aux dimensions relationnelle et identitaire, et vise à connaître la façon dont ces élèves se perçoivent, se considèrent, se positionnent, se définissent et réagissent dans cet environnement éducatif par rapport aux autres élèves. Des entretiens semi-directifs ont été réalisés auprès de dix élèves de deux écoles secondaires de la ville de Saguenay, au Saguenay–Lac-Saint-Jean. Dans l’ensemble, les extraits retenus font ressortir les vécus et les perçus des enjeux et des défis soulevés par leurs caractéristiques personnelles sur leur parcours scolaire. Les résultats attestent l’existence de perceptions diversifiées, mises en relief par différentes expériences et visant une reconnaissance sociale et une volonté de compensation de certaines ségrégations (p. ex. : le racisme), et nous invitent à nuancer la portée des victimisations se rapportant à la discrimination raciale. Nos résultats indiquent qu’il y a présence de comportements insidieux de microagressions (agresseurs) et d’évitement (victimes). Les élèves rencontrés, même s’ils se sentent en général bien et en sécurité à l’école, utilisent des stratégies d’adaptation et de refoulement devant les actes racistes.
Exploring Low-Speed Marine Diesel Engine Parameters through Advanced 3D Visualization with Delaunay Triangulation
Authors: Nikolaeva Dimitrichka , Nikolaev Evgeni , Yankova Radostina , Veselinov Deyan 
Published: February 2024

The article presents an algorithm for creating software leading to the optimization of the combustion process of marine engines. Parameters determining the Existing Ships Energy Efficiency Index (EEXI) related to ship type, capacity, and propulsion principle are considered. Test data on the characteristics of a two-stroke main engine, model HYUNDAI 6S60MC-C for six types of loads were used as the basis. To present the working field of the engine, the necessary calculations have been carried out and dependencies have been derived for the power and the specific fuel consumption as a function of the revolutions. The implementation includes the development of a small software program using Delaunay's triangulation algorithm to create 3D graphics, as well as Python libraries and methods.
Identification of m6A-associated autophagy genes in non-alcoholic fatty liver
Authors: Huang Ziqing , Luo Linfei , Wu Zhengqiang , Xiao Zhihua , Wen Zhili 
Published: February 2024

Background
Studies had shown that autophagy was closely related to nonalcoholic fat liver disease (NAFLD), while N6-methyladenosine (m6A) was involved in the regulation of autophagy. However, the mechanism of m6A related autophagy in NAFLD was unclear.

Methods
The NAFLD related datasets were gained via the Gene Expression Omnibus (GEO) database, and we also extracted 232 autophagy-related genes (ARGs) and 37 m6A. First, differentially expressed ARGs (DE-ARGs) and differentially expressed m6A (DE-m6A) were screened out by differential expression analysis. DE-ARGs associated with m6A were sifted out by Pearson correlation analysis, and the m6A-ARGs relationship pairs were acquired. Then, autophagic genes in m6A-ARGs pairs were analyzed for machine learning algorithms to obtain feature genes. Further, we validated the relationship between feature genes and NAFLD through quantitative real-time polymerase chain reaction (qRT-PCR), Western blot (WB). Finally, the immuno-infiltration analysis was implement, and we also constructed the TF-mRNA and drug-gene networks.

Results
There were 19 DE-ARGs and four DE-m6A between NAFLD and normal samples. The three m6A genes and five AGRs formed the m6A-ARGs relationship pairs. Afterwards, genes obtained from machine learning algorithms were intersected to yield three feature genes (TBK1, RAB1A, and GOPC), which showed significant positive correlation with astrocytes, macrophages, smooth muscle, and showed significant negative correlation with epithelial cells, and endothelial cells. Besides, qRT-PCR and WB indicate that TBK1, RAB1A and GOPC significantly upregulated in NAFLD. Ultimately, we found that the TF-mRNA network included FOXP1-GOPC, ATF1-RAB1A and other relationship pairs, and eight therapeutic agents such as R-406 and adavosertib were predicted based on the TBK1.

Conclusion
The study investigated the potential molecular mechanisms of m6A related autophagy feature genes (TBK1, RAB1A, and GOPC) in NAFLD through bioinformatic analyses and animal model validation. However, it is critical to note that these findings, although consequential, demonstrate correlations rather than cause-and-effect relationships. As such, more research is required to fully elucidate the underlying mechanisms and validate the clinical relevance of these feature genes.
Incidence and factors associated with postpartum depressive symptoms: a literature review / Incidência e fatores associados aos sintomas depressivos pós-parto: uma revisão de literatura
Authors: Caldeira Daniela Marcia Rodrigues , Ataíde Monção Rafael , Guimarães Cordeiro Paulo Eduardo , De Pinho Lucineia , Ramos Veloso Silva Rosângela , Santos Figueiredo Brito Maria Fernanda 
Published: February 2024

Objetivo: identificar na literatura científica as incidências dos sintomas depressivos pós-parto e os fatores associados. Método: revisão narrativa da literatura descrita conforme a declaração Preferred Reporting Items for Systematic Reviews and Meta-Analyses. A busca bibliográfica foi realizada na Biblioteca Virtual em Saúde. Foram elegíveis estudos observacionais com delineamento longitudinal, que utilizaram a Escala de depressão pós-parto de Edimburgo, disponíveis em texto completo, publicados nos anos de 2019 e 2020. Resultados: foram incluídos 17 artigos. A incidência de sintomatologia depressiva pós-parto variou de 0,18% a 27,87%. Os principais fatores de risco associados foram histórico de depressão, estresse e relação estressante familiar, baixo suporte social, transtornos psiquiátricos como comorbidade e experiência negativa ou complicações durante parto. Conclusões: a sintomatologia depressiva pós-parto atinge parcela expressiva das puérperas e se mantém como problema de saúde pública. Sugere-se a continuidade dos estudos que se relacionam com a temática no cenário nacional.
Transient multiphase model for the high‐temperature thermal treatment of wood
Authors: Younsi R. , Kocaefe D. , Poncsak S. , Kocaefe Y. 
Published: April 2006

AbstractThe hygrothermal behavior of wood at high temperature is analyzed, taking into account all the phases present such as wood, liquid water in free and bound forms, and water vapor. The moisture transport phenomenon includes water vapor convection and diffusion along with capillary water convection in the pores of the particle as well as bound water diffusion in the solid wood. Local thermodynamic equilibrium is assumed, which is represented by a sorption isotherm that relates the moisture contents in the solid and gas phases. The equations of the model were solved numerically using the commercial software Femlab® for the temperature and the moisture content profiles. The mathematical model predictions were compared with the experimental data and a reasonably good agreement was obtained. A parametric study was also carried out to determine the effects of several parameters such as heating rate, initial moisture content, and the sample thickness on the temperature and moisture content distributions within the samples during heat treatment. © 2006 American Institute of Chemical Engineers AIChE J, 2006
A prospective study of the prevalence of heparin‐induced antibodies and other associated thromboembolic risk factors in pediatric patients undergoing hemodialysis
Authors: Skouri Hadef , Gandouz Raoudha , Abroug Saoussen , Kraiem Imen , Euch Henda , Gargouri Jalel , Harbi Abdelaziz 
Published: April 2006

AbstractHeparin, which is used at high doses in hemodialysis patients, may induce antibodies favoring thromboembolic complications. We prospectively investigated the prevalence of heparin‐induced platelet‐reactive antibodies in a cohort of 38 pediatric hemodialysis patients, by means of heparin/platelet factor 4 (H/PF4) ELISA and heparin‐induced platelet activation assay (HIPA). We also assessed other acquired and congenital hypercoagulable states. Heparin‐induced antibodies were detected in 13 and 21% of patients with HIPA and ELISA, respectively. Anti‐H/PF4 antibodies were negatively correlated with the number of hemodialysis sessions. These antibodies disappeared after a median time of 6 months despite continuing heparin treatment. The prevalence of antiphospholipid antibodies was 21% (anticardiolipin 10.5%, anti‐β2GPI 13%, and lupus anticoagulant 5%). Blood levels of homocysteine, factor VIII, and fibrinogen were significantly higher and factor II levels were significantly lower in hemodialysis patients than in controls, whereas factor VII, factor IX, and natural coagulation inhibitor levels were similar in patients and controls. Overall, 26 of 38 patients had at least one biomarker of hypercoagulability, but only 1 patient, without anti‐H/PF4 antibodies, presented with thrombosis. In conclusion, heparin induces the transient production of anti‐H/PF4 antibodies in children undergoing hemodialysis, but other abnormalities probably contribute to hypercoagulability. These findings may help to improve the diagnosis and management of thrombotic events in hemodialysis patients. Am. J. Hematol. 81:328–334, 2006. © 2006 Wiley‐Liss, Inc.
Atom–Molecule Interactions on Transition Metal Surfaces: A DFT Study of CO and Several Atoms on Rh(100), Pd(100) and Ir(100)
Authors: Nieskens Davy L. S. , Curulla‐Ferré Daniel , Niemantsverdriet J. W. 
Published: April 2006

AbstractDensity functional theory (DFT) calculations have been performed to determine the interaction energy between a CO probe molecule and all atoms from the first three rows of the periodic table coadsorbed on Rh(100), Pd(100) and Ir(100) metal surfaces. Varying the coverage of CO or the coadsorbed atom proved to have a profound effect on the strength of the interaction energy. The general trend, however, is the same in all cases: the interaction energy becomes more repulsive when moving towards the right along a row of elements, and reaches a maximum somewhere in the middle of a row of elements. The absolute value of the interaction energy between an atom–CO pair ranges from about −0.40 eV (39 kJ mol−1) attraction to +0.70 eV (68 kJ mol−1) repulsion, depending on the coadsorbate, the metal and the coverage. The general trend in interaction energies seems to be a common characteristic for several transition metals.
Chemical composition of the essential oils of Stachys pubescens Ten.
Authors: Nik Z. Baher , Mirza M. 
Published: April 2006

AbstractThe essential oils of Stachys pubescens Ten. growing wild in Iran were examined by GC and GC–MS. The yield of total volatiles was 0.08% (w/w). A total of 21 compounds were characterized in the essential oil. The major components of the sample were germacrene D (37.7%), (Z)‐β‐ocimene (20.3%) and bicyclogermacrene (11.6%). Other compounds present in appreciable amounts were β‐pinene (7.5%), (E)‐β‐ocimene (5.5%), β‐bourbonene (5.2%), α‐pinene(2.5%), octen‐1‐ol acetate (1.3%), α‐cadinol (1.1%) and spathulenol (1%). Copyright © 2006 John Wiley & Sons, Ltd.