bluuebunny/crossref_metadata_2025_split huggingface dataset:
X‐ray Absorption and Emission Spectroscopy in Nanoscience and Lifesciences
Authors: Guo Jinghua 
Published: September 2007

Abstract
The sections in this article are

Introduction

Soft
X
‐ray Spectroscopy

Soft
X
‐ray Absorption Edges

Soft
X
‐ray Emission Spectroscopy

Soft
X
‐ray Absorption Spectroscopy

Resonant Soft
X
‐ray Emission Spectroscopy

Experimental Details

Chemical Sensitivity of Soft
X
‐ray Spectroscopy

Electronic Structure and Geometrical Structure

Hydrogen Bonding Effect

Charge and Spin States of Transition Metals

Electronic Structure and Nanostructure

Wide Bandgap Nanostructured Semiconductors

Cu
Nanoclusters

Zn
O
Nanocrystals

Electronic Structure and Molecular Structure

Hydrogen Bonding in Liquid Water

Molecular Structure in Liquid Alcohol and Water Mixture

Electronic Structure and Ion Solvations

Drugs in Water Solution

Electronic Structure of Bases in
DNA
Duplexes

Acknowledgments
Some New Advances and Challenges in Biological and Biomedical Materials Characterization
Authors: Braet Filip , Soon Lilian , Kelly Thomas F. , Larson David J. , Ringer Simon P. 
Published: September 2007

Abstract
The sections in this article are

Introduction

Modern Atom Probe Tomography: Principles, Applications in Biomaterials and Potential Applications for Biology

The Need for an Ideal Microscope

Field Ion Microscopy and the Modern Atom Probe Instrument

Applications in Biomaterials

Applications and Challenges for Biological Science

Atomic Force Microscopy

Introduction

Instrumentation

Live Cell Imaging

Summary

Cryo‐electron Microscopy

Introduction

Instrumentation

Cryo‐electron Microscopy Imaging

Summary

Conclusions

Acknowledgments
X‐ray Scattering Techniques for Characterization of Nanosystems in Lifesciences
Authors: Saw Cheng K. 
Published: September 2007

Abstract
The sections in this article are

Introduction

Brief Historical Background and Unique Properties

Scattering of X‐rays

Crystallography

Scattering from a Powder Sample

Scattering by Atomic Aggregates

Crystallite Size and Paracrystallinity

Production of
X
‐rays

Absorption of
X
‐rays

Instrumentation:
WAXS

Small Angle
X
‐ray Scattering

Dilute Systems

Highly Correlating Systems

SAXS
Instrumentation

Synchrotron Radiation

Concluding Remarks

Acknowledgment
The Physics and Modeling of Biofunctionalized Nanoelectromechanical Systems
Authors: Paul Mark R. , Solomon Jerry E. 
Published: September 2007

Abstract
The sections in this article are

Introduction

The Stochastic Dynamics of Micro‐ and Nanoscale Oscillators in Fluid

Fluid Dynamics at Small Scales

An Exact Approach to Determine the Stochastic Dynamics of Arrays of Cantilevers of Arbitrary Geometry in Fluid

An Approximate Model for Long and Slender Cantilevers in Fluid

The Stochastic Dynamics of a Fluid‐coupled Array of (
BIO
)
NEMS
Cantilevers

The Physics Describing the Kinetics of Target Analyte Capture on the Oscillator

Detecting Noise in Noise: Signal‐processing Challenges

Concluding Remarks

Acknowledgments
Mathematical and Computational Modeling: Towards the Development and Application of Nanodevices for Drug Delivery
Authors: Sinek John P. , Frieboes Hermann B. , Sivaraman Balakrishnan , Sanga Sandeep , Cristini Vittorio 
Published: September 2007

Abstract
The sections in this article are

Introduction

RES
Avoidance

A Statistical Model of Nanovector Surface Coverage

Modeling the Forces Mediating Protein Approach and Binding

Tumoral Vasculature and Hemodynamics

An Invasion Percolation Model of Vasculogenesis and Hemodynamics

Flow Simulations Using Anderson and Chaplain's Model

Particle Dynamics within the Tumoral Vasculature

Receptor–Ligand‐mediated Binding

Bell's Deterministic Model

A Stochastic Model

Intratumoral and Cellular Drug Kinetics and Pharmacodynamics

A Two‐Dimensional Model of Chemotherapy

Refinements of the Model

Conclusion
Nanolithography: Towards Fabrication of Nanodevices for Life Sciences
Authors: Ngunjiri Johnpeter Ndiangui , Li Jie‐Ren , Garno Jayne Carol 
Published: September 2007

AbstractThe sections in this article areIntroduction: Engineering Surfaces at the NanoscaleImmobilization of Biomolecules for Surface AssaysStrategies for Linking Proteins to SurfacesElectrostatic ImmobilizationCovalent ImmobilizationMolecular Recognition and Specific InteractionsNonspecific Physical Adsorption to SurfacesSAMChemistryMethods for Nanolithography with ProteinsBias‐induced Nanolithography ofSAMsForce‐induced Nanolithography ofSAMsDPNofSAMsand ProteinsLatex Particle Lithography with ProteinsDetection of Protein Binding at the NanoscaleFuture DirectionsAdvantages of Nanoscale DetectionDevelopment of Cantilever ArraysConcluding Remarks
Microcantilever‐based Nanodevices in the Life Sciences
Authors: Espinosa Horacio D. , Kim Keun‐Ho , Moldovan Nicolaie 
Published: September 2007

AbstractThe sections in this article areIntroductionMicrocantileversMicrofabrication of Miniaturized ProbesCantilever Probes for NanopatterningElastomericAFMProbesMonolithically Fabricated Conductive Diamond ProbesCantilevers with Integrated Micro‐ and NanofluidicsApertured Pyramidal TipsOpen‐channel Cantilevered MicrospottersClosed‐channel Cantilevered NanopipettesMicromachined Hypodermic Needle ArraysNFPsApplicationsPatterning ofDNAPatterning of ProteinsPatterning of VirusesConclusions and Outlook
Nanobioelectronics
Authors: Rinaldi Ross , Maruccio Giuseppe 
Published: September 2007

AbstractThe sections in this article areIntroductionBio‐self‐assembly and MotivationFundamentals of the Bio‐building BlocksDNAProteinsInterconnection, Self‐assembly and Device ImplementationInterconnecting MoleculesDelivering MoleculesDevices Based onDNAandDNABasesCharge Transfer inDNADNAConductivityNear‐ohmic Behavior (Activated Hopping Conductor)Semiconducting (Bandgap) BehaviorInsulating BehaviorDiscussion ofDNAConductivityOther Applications ofDNAin Molecular ElectronicsDevices Based on ProteinsConclusionsAcknowledgments
DNA
Nanodevices: Prototypes and Applications
Authors: Simmel Friedrich C. 
Published: September 2007

Abstract
The sections in this article are

Introduction

DNA
as a Material for Nanotechnology

Nanoscale Science

Biophysical and Biochemical Properties of Nucleic Acids

DNA
Nanoconstruction

Simple
DNA
Devices

Conformational Changes Induced by Small Molecules and Ions

Hybridization‐driven Devices

Towards Functional Devices

Walk and Roll

Interaction with Proteins

Information Processing

Switchable Networks and Hybrid Materials

Autonomous Behavior

Driving Devices with Chemical Reactions

Genetic Control

Conclusion

Acknowledgments
Towards the Realization of Nanobiosensors Based on G‐protein‐coupled Receptors
Authors: Pennetta Cecilia , Akimov Vladimir , Alfinito Eleonora , Reggiani Lino , Gorojankina Tatiana , Minic Jasmina , Pajot‐Augy Edith , Persuy Marie‐Annick , Salesse Roland , Casuso Ignacio , Errachid Abdelhamid , Gomila Gabriel , Ruiz Oscar , Samitier Josep , Hou Yanxia , Jaffrezic Nicole , Ferrari Giorgio , Fumagalli Laura , Sampietro Marco 
Published: September 2007

AbstractThe sections in this article areIntroductionPreparation and Immobilization ofGPCRson Functionalized SurfacesSignal TechniquesTheoretical ApproachThe Impedance Network ModelEquilibrium FluctuationsConclusionsAcknowledgments
Self‐assembly and Bio‐directed Approaches for Carbon Nanotubes: Towards Device Fabrication
Authors: Filoramo Arianna 
Published: September 2007

AbstractThe sections in this article areIntroductionCNTs: Basic Features, Synthesis and Device ApplicationsBasic FeaturesSynthesis of NanotubesDevice ApplicationsFabrication ofCNTTransistors and Self‐assembly ApproachesIn situCVDGrowthSelective Deposition ofCNTsbySAM‐assisted TechniquesMethodology and Key ParametersPerformance ofCNTFETsFabricated by theSAMMethodDNA‐directed Self‐assemblyThe Assembly of the ScaffoldSelective Attachment of theDNAScaffold on the Surface Microscale ElectrodesPositioning of Nano‐objects or Nanodevices on the ScaffoldRealization of Electrical Connections and CircuitryFabrication ofDNA‐directedCNTDevicesConclusion
Nanodevices for Biosensing: Design, Fabrication and Applications
Authors: Lechuga Laura M. , Zinoviev Kirill , Carrascosa Laura G. , Moreno Miguel 
Published: September 2007

AbstractThe sections in this article areIntroductionFrom Biosensor to Nanobiosensor DevicesOverviewBiological Functionalization of NanobiosensorsNanophotonic BiosensorsOverviewIntegrated Mach–Zehnder Interferometer (MZI) NanodeviceDesign and FabricationCharacterization and ApplicationsIntegration in MicrosystemsNanomechanical BiosensorsOverviewWorking PrincipleDetection SystemsDesign of a Standard Microcantilever SensorFabrication of a Standard Microcantilever SensorOptical Waveguide Microcantilever: Design and FabricationBiosensing Applications of Nanomechanical SensorsConclusions and Future GoalsAcknowledgments
Nanotechnology for Biomedical Devices
Authors: Montelius Lars 
Published: September 2007

AbstractThe sections in this article areIntroductionNanotechnologiesOverview of Nanotechnologies and NanotoolsNILOther Lithography TechniquesScanning ProbesApplicationsIntroductionBiomedical Applications based on Nanostructured Passive SurfacesSeparation, Concentration and Enriching StructuresMolecular Motors Transported in Nanometer ChannelsTopographical Structures, Cells and Guidance of NeuronsBiomedical Applications utilizing Active Nanostructured SurfacesProtein ChipsProtein InteractionsBiomedical Applications using NanowiresBiomedical Applications using NanoparticlesBiomedical Applications usingSPMTechnologyImaging of Biomolecules usingSPMForce Detection of Single Molecular EventsCantilever‐based Detection of Molecular EventsDiscussion and OutlookAcknowledgments
Biotoxicity of Metal Oxide Nanoparticles
Authors: Fond Amanda M. , Meyer Gerald J. 
Published: September 2007

AbstractThe sections in this article areIntroductionNanoparticles in the EnvironmentHow Nanoparticles are Introduced into Mammalian SystemsHealth ThreatsNanomaterials and BiotoxicityIron OxideTitanium DioxideDark StudiesUVIrradiation StudiesOther Metal OxidesConclusionsAcknowledgment
Dosimetry, Epidemiology and Toxicology of Nanoparticles
Authors: Kreyling Wolfgang G. , Semmler‐Behnke Manuela , Möller Winfried 
Published: September 2007

Abstract
The sections in this article are

Introduction

Overview

General Background

Epidemiological Evidence for Health Effect Associations with Ambient Particulate Matter

Toxicological Evidence for Ambient Particulate Matter Induced Adverse Health Effects

Inhaled Nanoparticle Dosimetry

Particle Measures

Deposition of Ultrafine Particles in the Respiratory System

Fate of Particles in the Lungs

Soluble Particle Compounds

Slowly Dissolving and Insoluble Particles Deposited on the Airway Wall

Slowly Dissolving and Insoluble Particles Deposited in the Alveolar Region

Macrophage‐mediated Particle Transport

Translocation of Ultrafine Particles into Systemic Circulation

Studies of Systemic Particle Translocation in Humans

Studies of Systemic Particle Translocation in Animals

Toxicological Plausibility of Health Effects Caused by Nanoparticles

Pulmonary Inflammation Induced by Ultrafine Particles

Systemic Inflammation and other Responses

Relevant Parameters in Nanoparticle Toxicology

Number Concentration and Surface Area

Particle Shape (Fibers and Nanotubes)

Transition Metals

Organic Compounds

Extrapolation of Health Effects Observed in Animals towards Human

Integrated Concept of Risk Assessment of Nanoparticles
Toxicity of Carbon Nanotubes and its Implications for Occupational and Environmental Health
Authors: Lam Chiu‐Wing , James John T. , McCluskey Richard , Holian Andrij , Hunter Robert L. 
Published: September 2007

AbstractThe sections in this article areIntroductionOverviewGeneral BackgroundCarbon Nanotubes and NanotechnologyManufactured Carbon Nanotubes: Their Synthesis, Properties, and Potential ApplicationsDiscovery and SynthesisPhysical and Chemical PropertiesApplicationsOccurrence of Carbon Nanotubes in the EnvironmentPotential Occupational Exposures and Environmental Impact of Manufactured Carbon NanotubesCombustion‐generated Carbon Nanotubes in the EnvironmentMWCNTFormation from Natural Gas Combustion IndoorsMWCNTsin Metropolitan Outdoor AirMWCNTsin Ancient IceConcern about Combustion‐generatedMWCNTsin the EnvironmentComparison of Physical Structures of Manufactured and Non‐manufactured Carbon NanotubesToxicological Studies and Toxicity of ManufacturedCNTsStudy ofSWCNTsin Guinea Pigs by Huczko et al. of Warsaw UniversityStudy ofSWCNTsin Mice by Lam et al. ofNASA‐JSCToxicology LaboratoryStudy ofSWCNTsin Rats by Warheit et al. of DuPont CompanyStudy ofSWCNTsin Mice by Shvedova et al. ofNIOSHStudy ofMWCNTsby Muller et al. of BelgiumHealth Risk ImplicationsToxicity Summary ofCNTsand Occupational Exposure RiskImpact ofSWCNTson Environmental HealthToxicity ofMWCNTsand Impact on Environmental HealthAcknowledgment
Toxicity of Nanomaterials – New Carbon Conformations and Metal Oxides
Authors: Krug Harald F. , Kern Katrin , Wörle‐Knirsch Jörg M. , Diabaté Silvia 
Published: September 2007

AbstractThe sections in this article areIntroductionNanoscale Materials and Adverse Health Effects: Precautionary MeasuresHazard Identification and Exposure EstimationProduction and Use of “New Carbon Modifications” and Metal OxidesHealth AspectsUptake and Possible Transport, Depots, and Accumulation in Living OrganismsBiological Effects on Cellular MechanismsMetal OxidesNew Carbon ModificationsPossible Hazards – Toxicological ImpactsRisk Characterization – A ConclusionOpportunities and Risks of NanomaterialsNew Materials without Risks?
Toxicology of Nanoparticles in Environmental Air Pollution
Authors: Donaldson Ken , Mills Nicholas , Newby David E. , MacNee William , Stone Vicki 
Published: September 2007

AbstractThe sections in this article areIntroductionHistory of Air PollutionIntroduction to Air Pollution ParticlesAdverse Effects ofPMin Epidemiological StudiesNanoparticles are an Important Component ofPMRole of Nanoparticles in Mediating the Adverse Pulmonary Effects ofPMEffects of Nanoparticles on the Cardiovascular SystemInflammation, Atherosclerosis and Plaque RuptureNanoparticle Translocation and Direct Vascular EffectsEndothelial Dysfunction and Endogenous FibrinolysisCoagulation and ThrombosisCardiac Autonomic DysfunctionEffects of Nanoparticles on the Liver and Gastrointestinal TractEffects ofNPon the Nervous SystemSummary
Nanoparticles for Neutron Capture Therapy of Cancer
Authors: Ichikawa Hideki , Tokumitsu Hiroyuki , Miyamoto Masahito , Fukumori Yoshinobu 
Published: September 2007

AbstractThe sections in this article areIntroductionPrinciple of Neutron Capture Therapy of CancerBoron Neutron Capture TherapyBoron CompoundsDelivery of Boron Using NanoparticlesApproaches toGdNCTTypical Research onGdNCTDelivery of Gadolinium using Lipid Emulsion (Gd‐nanoLE)Preparation ofGd‐nanoLEBiodistribution of Gadolinium after Intraperitoneal Administration ofGd‐nanoLEBiodistribution of Gadolinium after Intravenous Administration ofGd‐nanoLEDelivery of Gadolinium using Chitosan Nanoparticles (Gd‐nanoCPs)Preparation ofGd‐nanoCPsGd‐DTPARelease Property ofGd‐nanoCPsGd‐DTPARetention in Tumor Tissue after Intratumoral InjectionIn vivoGrowth Suppression of Experimental Melanoma Solid TumorBioadhesion and Uptake ofGd‐nanoCPin Three Different Cell LinesConclusions
Nanomaterials for Controlled Release of Anticancer Agents
Authors: Kim Do Kyung , Jo Yun Suk , Dobson Jon , El Haj Alicia , Muhammed Mamoun 
Published: September 2007

AbstractThe sections in this article areIntroductionNanoparticles for Biomedical ApplicationsFirst Generation NanoparticlesSecond Generation NanoparticlesAdvanced Generation NanoparticlesPolymer Materials for Drug Delivery SystemsDesign of Drug Delivery Vectors and Their PrerequisitesPolymeric NanoparticlesInorganic NanoparticlesMetallic NanoparticlesKinetics of the Controlled Release of Anticancer AgentsDiffusion ModelDissolution ModelKinetics of the Indomethacin (IMC, 1‐[p‐chlorobenzoyl]‐2‐methyl‐5‐methoxy‐3‐indoleacetic acid) ReleaseControlled Release of Anticancer AgentsAlkylating AgentsChlorambucilCyclophosphamideCarmustineAntimetabolic AgentCytarabineFluorouracil (FU)MethotrexateAnticancer AntibioticsActinomycinDBleomycinDaunorubicinFuture Directions
Critical Analysis of Cancer Therapy using Nanomaterials
Authors: Juillerat‐Jeanneret Lucienne 
Published: September 2007

AbstractThe sections in this article areIntroductionAnticancer TherapiesCharacteristics of Nanoparticles for Cancer TherapyNanovectorsBiological IssuesNanoparticle Targeting: Passive or ActiveNanovectors in Biomedical Applications: Drug Delivery Systems (DDS) for CancerPhysicochemical Drug DeliveryBiological Drug DeliveryChemical Drug DeliveryNanoparticles for Anticancer Drug DeliveryExisting SystemsSystems under Development and ChallengesNanoparticles for Drug Delivery in Clinical Use or under Clinical EvaluationDoxorubicin FamilyPaclitaxel (Taxol)5‐FluorouracilTamoxifenCisplatinCampthotecinsMethotrexateNew Experimental Drugs and TherapiesProteins, Peptides, their Inhibitors and AntagonistsNew DrugsNew Therapeutic Approaches: Photodynamic Therapy (PDT)Gene TherapyNanoparticle for Gene Delivery: Non‐chitosan and Chitosan‐type PolymersNew ApproachesImprovement of Biological CharacteristicsNew Technological ApproachesSuperparamagnetic Iron Oxide Nanoparticles (SPIONs) as Magnetic Drug NanovectorsTargetingPassive TargetingActive TargetingTargeting Cancer‐associated CellsTargeting Cancer MarkersIntracellular Drug DeliveryDevelopment of the Necessary Chemistry: Synthetic Routes and Linkers for ConjugationOvercoming the Mechanisms of Resistance to Therapy of CancersToxicity IssuesConclusionsOpportunities and Challenges of Nanomedicine in Cancer
Nanoparticles for Thermotherapy
Authors: Jordan Andreas , Maier‐Hauff Klaus , Wust Peter , Johannsen Manfred 
Published: September 2007

AbstractThe sections in this article areIntroductionThermotherapy following Intratumoral Administration of Magnetic NanoparticlesFerromagnetic Embolization HyperthermiaFirst Clinical Experiences with Thermotherapy using Magnetic Nanoparticles: MagForce NanotherapyFeasibility Study on Thermotherapy using Magnetic Nanoparticles in Recurrent Glioblastoma MultiformeFeasibility Study on Thermotherapy using Magnetic Nanoparticles in Recurrent and Residual TumorsFeasibility Study on Thermotherapy using Magnetic Nanoparticles in Recurrent Prostate Carcinoma
Ferromagnetic Filled Carbon Nanotubes as Novel and Potential Containers for Anticancer Treatment Strategies
Authors: Moench Ingolf , Meye Axel , Leonhardt Albrecht 
Published: September 2007

Abstract
The sections in this article are

Introduction

Prostate Cancer

Incidence, Risk Factors and Diagnostic Criteria

Treatment Options, Outcome and Limits

MWCNT
Model

Carbon Nanotubes

General Remarks

Preparation and Structure of Filled Multi‐walled Carbon Nanotubes

Synthesis of Ferromagnetic Filled Multi‐walled Carbon Nanotubes

Crystallographic Structure of Core Material in Filled Multi‐walled Carbon Nanotubes

Growth Mechanism of Multi‐walled Carbon Nanotubes

Post‐treatment: Opening, Filling and Closing of
MWCNTs

Magnetism in Nano‐sized Materials

General Remarks

Magnetization in Nano‐sized Materials

Influence of the Dimensions on the Magnetization Distribution

Anisotropy and Interaction

Magnetic Reversal

Magnetic Properties of Filled Multi‐walled Carbon Nanotubes

Heat Generation

General Remarks

Requirements for the Development of Materials for Hyperthermia and Magnetism

Specific Absorption Rate (
SAR
)

Study Results for
In Vitro
and
In Vivo
Applications of ff‐
MWCNTs

Efficient Endocytosis
In Vitro
, Lipid‐mediated Could Enhance the Internalization Rate and Efficiency

Production of Two Types of ff‐
MWCNTs
for
In Vivo
Application

Outlook/Next Steps in Evaluation of these
fff
‐
MWCNTs

Acknowledgments
Liposomes, Dendrimers and other Polymeric Nanoparticles for Targeted Delivery of Anticancer Agents – A Comparative Study
Authors: Zhang Yong , Chatterjee Dev K. 
Published: September 2007

AbstractThe sections in this article areIntroductionCancer Chemotherapy: so Far, but not so GoodNanoparticles and Drug Delivery in Cancer: a new RoadImportance of Nanoparticles in Cancer TherapyAn Overview of Targeting MethodsMeans to the End: Methods for TargetingPassive TargetingMagnetic Targeting of NanoparticlesLigands for Active TargetingMonoclonal Antibodies against Tumor‐specific AntigensTargeting the Angiogenic ProcessFolic Acid and Cancer TargetingTransferrin as a Targeting LigandOther Targeting LigandsTargeting with Different Types of NanoparticlesLiposomes in Cancer TargetingBeyond ImmunoliposomesDendrimersOther Polymeric NanoparticlesConclusion
Colloidal Systems for the Delivery of Anticancer Agents in Breast Cancer and Multiple Myeloma
Authors: Maillard Sébastien , Fattal Elias , Marsaud Véronique , Sola Brigitte , Renoir Jack‐Michel 
Published: September 2007

AbstractThe sections in this article areIntroductionHormone Therapy in Breast CancersMolecular Mechanisms of Estrogen Action in Breast CancersClassicalER‐ligand andERE‐dependent MechanismERE‐independent PathwayER‐ligand‐independent Pathway“Non‐genomic” PathwayDifferential Activity of AntiestrogensThe Need to Encapsulate AntiestrogensMultiple MyelomaCurrent TreatmentsNew Biological Therapies forMMTreatmentIncidence of Estrogens and Antiestrogens on Multiple MyelomaColloidal Systems for Antiestrogen DeliveryNanoparticles Charged withAEsin Breast CancerLiposomes Charged withRU58668 inMMTumor‐targeted Drug‐loaded Colloidal SystemsConclusions and PerspectivesAcknowledgments
Magnetic Resonance Nanoparticle Probes for Cancer Imaging
Authors: Jun Young‐wook , Jang Jung‐tak , Cheon Jinwoo 
Published: September 2007

AbstractThe sections in this article areIntroductionMagnetic Nanoparticle Contrast AgentsSilica‐ or Dextran‐coated Iron Oxide Contrast AgentsMagnetoferritinMagnetodendrimers and MagnetoliposomesNew Type of Contrast Agent: Non‐hydrolytically Synthesized High Quality Iron Oxide NanoparticlesIron Oxide Nanoparticles in MolecularMRImagingInfarct and InflammationAngiogenesisApoptosisGene ExpressionCancer ImagingSummary and Outlook
Nanoprobe‐Based Affinity Mass Spectrometry for Cancer Marker Protein Profiling
Authors: Huang Li‐Shing , Chien Yuh‐Yih , Chen Shu‐Hua , Lin Po‐Chiao , Wang Kai‐Yi , Chou Po‐Hung , Lin Chun‐Cheng , Chen Yu‐Ju 
Published: September 2007

AbstractThe sections in this article areIntroductionFabrication and Biomedical Applications of NanoparticlesFabrications and Properties of NanoparticlesMetal Nanoparticles in Cancer DiagnosisPrinciples of Mass SpectrometryMatrix‐assisted Laser Desorption/Ionization Time‐of‐flight Mass SpectrometryAffinity Mass SpectrometryNanoprobe‐based Affinity Mass Spectrometry (NBAMS)Preparation of Nanoprobes and WorkflowProof‐of‐principle ExperimentKinetic Study of the Nanoscale ImmunoreactionDetection Limit and Concentration Effect of Nanoprobe‐based ImmunoassayHuman Plasma and Whole Blood Analysis by Nanoprobe‐based Affinity Mass SpectrometrySelected Protein Profiling from Human PlasmaComparison of Nanoscale and Microscale ImmunoassaySuppression of Nonspecific Binding on Magnetic NanoparticlesEnrichment of Target Antigen in Human PlasmaPlasma Protein Profiling in Normal Individuals and in PatientsMultiplex AssayWorkflow of Multiplexed AssayScreening for Patient and Healthy IndividualsFuture OutlookAcknowledgments