bluuebunny/crossref_metadata_2025_split huggingface dataset:
Lymphatic and vascular anatomy define surgical principles for bowel-sparing radical treatment of ileal tumors
Authors: Vasic Teodor , Stimec Milena , Stimec Bojan Vladimir , Ignjatovic Dejan 
Published: February 2025

Abstract

Background
There is no consensus on the level of vascular ligation and the extent of lymphadenectomy in the treatment of ileal tumors. This study aims to define lymphovascular bundles of the terminal ileal artery (TIA) and subsequent ileal arteries. It also aims to extrapolate results from two distinct methodologies to define the level of arterial ligation and the dissection area for radical and bowel-sparing surgery.

Methods
Analysis of 3D-CT mesenteric vascular reconstructions of 104 operated patients. The second dataset consisted of 5 human cadavers for anatomical dissection. In one case, harvested viscera underwent the superior mesenteric artery (SMA) perfusion after ligation of the TIA.

Results
The calibers of the first three ileal arteries were: 2.67 ± 0.98 mm, 2.22 ± 0.78 mm, 2.31 ± 1.24 mm. The distances from the first three ileal arteries to the ileocolic artery (ICA) origin were: 12.45 ± 8.79 mm, 27.45 ± 13.47 mm, and 43.04 ± 16.94 mm. The SMA trifurcated in 61 (59%) of cases and bifurcated in 43 (41%). In 89 cases, the combined ICA + first jejunal artery caliber (6.7 ± 1.6 mm) was greater than the TIA caliber (4.84 ± 1.42 mm). The ileal artery lymphatic clearances were 0.85 mm to the preceding vessel. In the D3 volume at the ICA origin, 3–8 lymph nodes were observed. Internal calibers of the small bowel marginal artery, after selective TIA ligation and the SMA perfusion, were: proximal jejunal part 0.417 mm and distal ileal part 0.291 mm.

Conclusions
Ileal tumors are irrigated through the TIA, which can be ligated without consequences. Lymphadenectomy should encompass the adjacent vessels (1st jejunal artery, ICA) and can include the central nodes (D3 volume) at the surgeon’s preference. Preserving the adjacent vessels and the marginal artery is paramount for bowel-sparing surgery.

Graphical abstract
Exploring motivations of peer supporters for caregivers of patients with hematological malignancies—a qualitative study
Authors: Myrhøj Cæcilie Borregaard , Nielsen Iben Husted , Visler Camilla Louise , Nørskov Kristina Holmegaard , Piil Karin , Jarden Mary 
Published: February 2025

Abstract

Purpose
Social support interventions, particularly peer support from former family caregivers, offer unique assistance to caregivers of newly diagnosed patients. Since voluntary peer support is driven by personal choice, understanding the motivations for participating and how motivation evolves over time is essential. This study explores the motivations for becoming a peer support provider for family caregivers of patients with hematological malignancies and how motivation changes over time.

Methods
This qualitative study encompasses 18 semi-structured interviews with family caregivers providing peer support (N = 11) at two time points: (1) just after certification as peer supporters but prior to starting the peer support program and (2) at the 6-week mark of their 12-week peer support program. Interpretive phenomenological analysis was used to analyze the data.

Results
Motivation for participating in a voluntary peer-to-peer support program as a peer support provider center on four main themes: “Driven by past experiences”, “Moral obligation is intrinsic to identity”, “Meaningful use of personal experiences”, and “Guiding new caregivers”. Motivation was influenced during the support program, particularly by the presence or absence of feedback from family caregivers and by participation in network meetings with other peer support providers.

Conclusions
This study emphasizes the importance of networking meetings for family caregiver peer support providers, as they facilitate exchange of knowledge and insights and discussion of challenges and rewards and provide an ongoing support and motivation. It also highlights the untapped potential of volunteering to provide unique social support benefiting both the family caregiver recipient of support and the support provider.
Material recovery as a strategy for landfill remediation: a case study of Nkolfoulou landfill, Cameroon
Authors: Ndiforngu Ateh Suh Nkwekeu , Raga Roberto , Mfokou Abdou Nasser Njoya , Tan Paula Ngo Fin , Chounna Gergino Yemele 
Published: February 2025

Abstract
This study sought to evaluate the potential advantages of recovering both fresh and old waste from the Nkolfoulou landfill as a remediation technique, a means of gaining airspace, and a means of retrieving material, thus increasing the flow of secondary resources in the local economy. The current treatment procedures were assessed. Waste sampling and characterization, largely based on an adapted version of the French standard for household waste characterization, was carried out for six districts of the capital of Cameroon (Yaounde1- Yaoundé 6) for fresh and old waste samples. The results revealed the low efficiency of the current waste management strategy and highlighted that fresh waste recovery would yield a potential of roughly 22% of recoverable material and a 29.2% gain in airspace per ha which is more significant than the current system. This would consequently prolong the lifespan of the landfill. In addition, landfill mining had a recovery potential of 19%, but to address the current state of the landfill and economy, pretreatment of waste by material recovery of fresh waste proved more feasible and beneficial. It would be advised as a primary barrier and preferred to landfill mining.
A Proof-of-Concept Solution for Co-locating 2D Histology Images in 3D for Histology-to-CT and MR Image Registration: Closing the Loop for Bone Sarcoma Treatment Planning
Authors: Phillips Robert , Zakkaroff Constantine , Dittmer Keren , Robilliard Nicholas , Baer Kenzie , Butler Anthony 
Published: February 2025

Abstract
This work presents a proof-of-concept solution designed to facilitate more accurate radiographic feature characterisation in pre-surgical CT/MR volumes. The solution involves 3D co-location of 2D digital histology slides within ex-vivo, tumour tissue CT volumes. Initially, laboratory dissection measurements seed the placement of histology slices in corresponding CT volumes, followed by in-plane point-based registration of bone in histology images to the bone in CT. Validation using six bisected canine humerus ex-vivo CT datasets indicated a plane misalignment of 0.19 ± 1.8 mm. User input sensitivity was assessed at 0.08 ± 0.2 mm for plane translation and 0–1.6° deviation. These results show a similar magnitude of error to related prostate histology co-location work. Although demonstrated with a femoral canine sarcoma tumour, this solution can be generalised to various orthopaedic geometries and sites. It supports high-fidelity histology image co-location to improve understanding of tissue characterisation accuracy in clinical radiology. This solution requires only minimal adjustment to routine workflows. By integrating histology insights earlier in the presentation-diagnosis-planning-surgery-recovery loop, this solution guides data co-location to support the continued evaluation of safe pre-surgical margins.
Explained Deep Learning Framework for COVID-19 Detection in Volumetric CT Images Aligned with the British Society of Thoracic Imaging Reporting Guidance: A Pilot Study
Authors: Fouad Shereen , Usman Muhammad , Kabir Ra’eesa , Rajasekaran Arvind , Morlese John , Nagori Pankaj , Bhatia Bahadar 
Published: February 2025

Abstract
In March 2020, the British Society of Thoracic Imaging (BSTI) introduced a reporting guidance for COVID-19 detection to streamline standardised reporting and enhance agreement between radiologists. However, most current DL methods do not conform to this guidance. This study introduces a multi-class deep learning (DL) model to identify BSTI COVID-19 categories within CT volumes, classified as ‘Classic’, ‘Probable’, ‘Indeterminate’, or ‘Non-COVID’. A total of 56 CT pseudoanonymised images were collected from patients with suspected COVID-19 and annotated by an experienced chest subspecialty radiologist following the BSTI guidance. We evaluated the performance of multiple DL-based models, including three-dimensional (3D) ResNet architectures, pre-trained on the Kinetics-700 video dataset. For better interpretability of the results, our approach incorporates a post-hoc visual explainability feature to highlight the areas of the image most indicative of the COVID-19 category. Our four-class classification DL framework achieves an overall accuracy of 75%. However, the model struggled to detect the ‘Indeterminate’ COVID-19 group, whose removal significantly improved the model’s accuracy to 90%. The proposed explainable multi-classification DL model yields accurate detection of ‘Classic’, ‘Probable’, and ‘Non-COVID’ categories with poor detection ability for ‘Indeterminate’ COVID-19 cases. These findings are consistent with clinical studies that aimed at validating the BSTI reporting manually amongst consultant radiologists.
Distributed inexact Newton method with adaptive step sizes
Authors: Jakovetić Dušan , Krejić Nataša , Malaspina Greta 
Published: February 2025

Abstract
We consider two formulations for distributed optimization wherein N nodes in a generic connected network solve a problem of common interest: distributed personalized optimization and consensus optimization. A new method termed DINAS (Distributed Inexact Newton method with Adaptive step size) is proposed. DINAS employs large adaptively computed step sizes, requires a reduced global parameters knowledge with respect to existing alternatives, and can operate without any local Hessian inverse calculations nor Hessian communications. When solving personalized distributed learning formulations, DINAS achieves quadratic convergence with respect to computational cost and linear convergence with respect to communication cost, the latter rate being independent of the local functions condition numbers or of the network topology. When solving consensus optimization problems, DINAS is shown to converge to the global solution. Extensive numerical experiments demonstrate significant improvements of DINAS over existing alternatives. As a result of independent interest, we provide for the first time convergence analysis of the Newton method with the adaptive Polyak’s step size when the Newton direction is computed inexactly in centralized environment.
Psychological drivers shaping mobile learning utilization among visually impaired university students
Authors: Şahin Ferhan 
Published: February 2025

Abstract
Understanding the various factors influencing the utilization of mobile learning is pivotal to ensuring that visually impaired students can fully harness its benefits. However, there exists a notable gap in empirical research concerning the influence of psychological needs on the adoption of mobile learning among visually impaired students. This study delves into exploring mobile learning adoption among university students with visual impairment, focusing on the influence of basic psychological needs using a path modeling approach grounded in the Technology Acceptance Model and Self-Determination Theory. The investigation involves 341 visually impaired students enrolled in an open education faculty of a state university. Confirmatory factor analysis, structural equation modeling, and bootstrapping were employed for the analysis. The results affirm the model’s substantial explanatory power, revealing that the constructs—perceived ease of use (81.5%), perceived usefulness (84.8%), and behavioral intentions (74.7%)—are well elucidated by the proposed framework. The results underscore the significance of competence and relatedness in influencing acceptance and intention to use mobile learning among visually impaired students, highlighting the pivotal role of fostering skills mastery and social support in shaping technology adoption. Intriguingly, certain relationships, notably autonomy- > perceived usefulness and perceived usefulness- > behavioral intention, were deemed insignificant, revealing nuanced dynamics in acceptance and use. This study contributes valuable insights into understanding the complex interplay between basic psychological needs and mobile learning adoption, emphasizing the necessity for tailored interventions and support mechanisms to foster inclusive and effective technology use in the educational journey of visually impaired students.
Ovarian function and response to gonadotropins after prolonged perfusion of whole ewe ovaries in a bioreactor
Authors: Hatekar Prajakta , Tsiartas Panagiotis , Gómez Lucía de Miguel , Mateoiu Claudia , Sehic Edina , Hellström Mats , Patrizio Pasquale , Akouri Randa 
Published: February 2025

Abstract

Purpose
Fertility preservation for pre-pubertal girls undergoing gonadotoxic cancer treatments and women with systemic cancers at high risk for ovarian metastasis remains limited. Current options, such as ovarian cortex transplantation, risk reintroducing malignant cells. This study presents a novel approach focusing on ex vivo folliculogenesis and mature oocyte retrieval for cryopreservation, mitigating this risk.

Methods
This experimental study optimized an ex vivo ovarian perfusion system in sheep, refining gonadotropin stimulation to yield mature oocytes. Eleven ovaries were divided into two experimental subgroups: Group 1 (n = 5) and Group 2 (n = 6). Both groups were perfused in a bioreactor for 4 to 8 days under distinct perfusion protocols, differing in gonadotropin administration overnight—Group 1 did not receive overnight gonadotropin stimulation, whereas Group 2 received basal gonadotropin stimulation overnight. Assessments included follicular proliferation, oocyte maturity, apoptosis, ovarian function-related gene expression, and the levels of hormones, metabolites, and electrolytes in the culture medium, compared across subgroups.

Results
The protocol without overnight ovarian stimulation yielded mature MII oocytes, despite fewer secondary follicles and overexpression of the pro-apoptotic BAX gene. Conversely, ovaries with overnight stimulation yielded mostly GV-MI oocytes and exhibited reduced secondary follicle proliferation and higher HIF1A expression. Hormone levels, metabolites, and electrolytes remained stable across groups and time.

Conclusions
This study is the first to report the successful harvesting of MII oocytes following extended ex vivo perfusion of intact ewe ovaries, highlighting the potential of the perfusion model to support advanced follicular development. Further investigations are warranted to elucidate underlying mechanisms and refine protocol efficiency.
Infill pattern strategy impact on the cross-sectional area at gauge length of material extrusion 3D printed polylactic acid parts
Authors: Cañero-Nieto J. M. , Campo-Campo R. J. , Díaz-Bolaño I. , Ariza-Echeverri E. A. , Deluque-Toro C. E. , Solano-Martos J. F. 
Published: February 2025

Abstract
This study aims to explore the impact of various infill patterns on the mechanical properties of 3D-printed polylactic acid (PLA) specimens, particularly focusing on the minimum cross-sectional area, which correlates with mechanical strength. A randomized controlled trial design was employed, testing four different infill patterns: concentric, gyroid, 3D honeycomb, and rays. Each pattern was printed in PLA using a standard material extrusion 3D printer. The specimens were subjected to tensile stress using a universal testing machine, following the ASTM D638-14 standard. The cross-sectional area at gauge length was calculated using the line-plane intersection method from GCODE analysis, highlighting the minimum cross-sectional area: the weakest sections theoretically prone to failure. This work involved testing specimens with varying infill patterns to determine their influence on the mechanical integrity and performance of the parts. The concentric infill pattern exhibited the highest relative line-plane intersection points (RLPI) and maintained minimal variability in mechanical properties across the sample size. Experimental results demonstrated that different infill patterns significantly affect tensile strength, with the concentric pattern providing the most favorable outcomes in terms of strength and reliability. The choice of infill pattern in material extrusion 3D printing of PLA significantly influences the mechanical properties, particularly the tensile strength and distribution of material within the cross-sectional area. The concentric pattern consistently outperformed other types in maintaining structural integrity under stress. These findings provide crucial insights for optimizing 3D printing settings to enhance the durability and performance of printed parts.
Does Happiness Foster Social Bonds? A Research Synthesis Using an Online Finding Archive
Authors: Sharma Nidhi , Agrawal Shruti , Veenhoven Ruut 
Published: February 2025

Abstract
It is widely agreed that social bonds should be strengthened but is not clear how that can be achieved. One way could be to foster happiness, since happiness seems to foster social bonds. If so, two desirables can be achieved together: happier people and stronger social bonds. This raises the following questions: Does happiness really foster social bonds? If so, is that effect universal? How strong is the effect? Does the strength vary across persons and situations? What are the causal mechanisms? To answer these questions we took stock of the available research findings, restricting to longitudinal studies examining the effect of earlier happiness on later social bonds. We used the World Database of Happiness (WDH), a findings-archive consisting of data about happiness in the sense of the subjective enjoyment of one’s life-as-a-whole. To date, the WDH contains the results of 16 follow-up studies on the relation between earlier happiness and later social bonds, which together yield 33 findings. We found strong evidence for a causal effect of happiness on the formation and stability of primary social bonds on happiness, in particular, with marriage, love and friendship. Happiness fosters social bonds and this effect seems to be universal. Consequently, fostering happiness can be used as a means to strengthen social bonds. This is another reason to opt for policies that aim to achieve greater happiness for a greater number.
Mo Money Mo Problems? Economic Freedom and Subjective Happiness in Europe, 2010–2020
Authors: Martinussen Pål E. , Hilland Geir H. 
Published: February 2025

Abstract
It is widely held that economic freedom is fundamental for a society’s prosperity and growth, and neoliberalism has now become the dominant ideology in shaping our world. While a large literature on economic freedom has documented mainly favourable impacts on economic outcomes, only a handful of studies have examined the link between economic freedom and life quality. Building on the most recent data available on European countries, we combined the Index of Economic Freedom from the Frasier Institute with data from the World Bank, Varieties of Democracy and the European Social Survey in the period 2010–2020, allowing for a multilevel analysis of a total of nearly 199,000 respondents from 28 countries. At the individual level, the analysis controlled for the respondents’ demographic background, socio-economic status and social trust. At the country level we controlled for levels of democracy through a composite index. The results for the aggregate models indicate that there is a reversed U-shaped curvilinear association between economic freedom and happiness. However, the results of the disaggregate models, where we tested the associations between each of the individual components of economic freedom and happiness, indicate a reversed U-shape for only one of the five components, sound money. The one-sided focus on minimal government in the research and discourse on economic freedom seems mis-specified. By treating economic freedom as a general composite measure, we run the risk of dramatically over-simplifying the processes at play. Recent developments in multilevel methods and improved access to data should inspire further studies of how economic freedom can serve and benefit citizens’ well-being and thus contribute to well-functioning societies.
The M-PerFeCt questionnaire: assessing higher education students’ motivation in a peer feedback context
Authors: Pereira Priyanka D. , Heitink Maaike C. , Schildkamp Kim , Veldkamp Bernard P. 
Published: February 2025

Abstract
In higher education, teacher feedback has increasingly been replaced or complemented with peer feedback. But, when students lack motivation, they may not participate in the peer feedback activity adequately, and, thus, the activity may not have the desired effect. Motivation is a complex, difficult-to-measure concept, and existing questionnaires for assessing students’ motivation in the context of a peer feedback intervention in higher education have each considered only a few aspects of motivation to learn or motivation to participate in the peer feedback activity. However, a questionnaire that concurrently assesses (almost) all aspects of higher education students’ motivation in a peer feedback context is needed for researchers and practitioners to obtain a complete picture of students’ motivation, so they can determine whether and how this motivation needs to be improved. Therefore, this study aimed to develop the Motivation in a Peer Feedback Context (M-PerFeCt) questionnaire. Methodological pluralism was used to capture this complex concept while ensuring more rigorous scientific results, including eliciting a student and expert appraisal of the questionnaire and collecting responses to the questionnaire from higher education students in The Netherlands and performing exploratory and confirmatory factor analyses. Pre-activity and post-activity forms of the questionnaire were developed and validated. The final questionnaire comprised 66 items in 19 scales. The questionnaire provides insight into the underlying structure of students’ motivation in a peer feedback context. Additionally, it enables teachers and researchers to assess students’ motivation in a peer feedback context.
Haeccities and the triviality of the identity of indiscernibles
Authors: Elgin Samuel Z. 
Published: February 2025

Abstract
The Identity of Indiscernibles is the principle that objects cannot differ only numerically. It is widely held that one interpretation of this principle is trivially true: the claim that objects that bear all of the same properties are identical. This triviality ostensibly arises from haecceities (properties like is identical to a). I argue that this is not the case; we do not trivialize the Identity of Indiscernibles with haecceities, because it is impossible to express the haecceities of indiscernible objects. I then argue that this inexpressibility generalizes to all of their trivializing properties. Whether the Identity of Indiscernibles is trivially true ultimately turns on whether we can quantify over properties that we cannot express.