bluuebunny/crossref_metadata_2025_split huggingface dataset:
Numerical analysis of jet impingement cooling with elongated nozzle holes on a curved surface roughened with V-shaped ribs
Authors: Yalçınkaya Orhan , Durmaz Ufuk 
Published: March 2024

AbstractNumerical studies were performed in this study to analyze the effect of dimensionless elongated injection holes (G/d = 0.5, 2.0, 4.0, 8.0) on heat and flow characteristics on rib-roughened surfaces with an array of inclined impingement jets. Experimental and numerical data from existing literature were used to validate the numerical solution procedure’s heat transfer and flow characteristics in the semicircular test section. The turbulence equations were solved using the SST k-ω turbulence model by varying the Reynolds number from 5000 to 25,000. The curvature effect and staggered array pattern created an additional stagnation region between adjacent impinging jets on smooth surfaces, leading to a low heat transfer zone. Rectangular cross-sectional V-shaped ribs (VSR) were placed in regions where the stagnation point occurs to eliminate this disadvantage. The effect of different normalized rib heights (Hr/d = 0, 0.2, 0.3, 0.4) and rib angles (α = 30°, 45°, 60°, 90°) on the curved surface was also investigated to increase convective heat transfer performance and achieve more homogenous heat transfer distribution by relatively reducing the effect of thermal stresses. Flow properties, area-averaged and local Nusselt number variations on smooth and ribbed surfaces, and the thermal performance criterion (TPC) were investigated in detail. The results indicated an increase in overall heat transfer and a more evenly distributed measurement region compared to the conventional (unextended jet and smooth surface) jet impingement configuration. The most significant heat transfer enhancement from combining the elongated jets with VSR was 47.23% at Hr/d = 0.2 by reducing the G/d to 0.5. In addition, the highest TPC was determined as 1.07 on the proposed model with G/d = 2.0 and Hr/d = 0.2 at Re = 25,000.
Machine learning approach for satellite-based subfield canola yield prediction using floral phenology metrics and soil parameters
Authors: Fernando Hansanee , Ha Thuan , Nketia Kwabena Abrefa , Attanayake Anjika , Shirtliffe Steven 
Published: March 2024

AbstractEarly monitoring of within-field yield variability and forecasting yield potential is critical for farmers and other key stakeholders such as policymakers. Remote sensing techniques are progressively being used in yield prediction studies due to easy access and affordability. Despite the increasing use of remote sensing techniques for yield prediction in agriculture, there is still a need for medium-resolution satellite imagery when predicting canola yield using a combination of crop and soil information. In this study, we investigated the utility of remotely sensed flowering information from PlanetScope (at 4 m) satellite imagery combined with derived soil and topography parameters to predict canola yield. Our yield prediction model was trained and validated using data from 21 fields managed under variable rate seed and fertilizer application, including cleaned harvester yield maps, soil, and topography maps. To quantify the flowering intensity of canola, 9 vegetation indices (VIs) were calculated using spectral bands from PlanetScope imagery acquired for the reproductive stages of canola. We created five random forest regression models using different subsets of covariates, including VIs, soil, and topography features, to predict canola yield within the season. Using a random forest regression algorithm, we recorded accuracies ranging from poor to best performing using coefficient of determination and root mean squared error (R2: 0.47 to 0.66, RMSE: 325 to 399 kg ha−1). The optimal subset of covariates identified electrical conductivity (EC), Normalized Difference Yellowness Index, and Canola Index as the key variables explaining within-spatial variability in canola yield. Our final model exhibited a validation R2 of 0.46 (RMSE = 730 kg ha−1), demonstrating the potential of medium-resolution satellite imagery during the flowering stage to detect and quantify sub-field spatial and temporal floral phenology changes when predicting canola yield.
On the simulation and interpretation of substrate-water exchange experiments in photosynthetic water oxidation
Authors: Chernev Petko , Aydin A. Orkun , Messinger Johannes 
Published: March 2024

AbstractWater oxidation by photosystem II (PSII) sustains most life on Earth, but the molecular mechanism of this unique process remains controversial. The ongoing identification of the binding sites and modes of the two water-derived substrate oxygens (‘substrate waters’) in the various intermediates (Si states, i = 0, 1, 2, 3, 4) that the water-splitting tetra-manganese calcium penta-oxygen (Mn4CaO5) cluster attains during the reaction cycle provides central information towards resolving the unique chemistry of biological water oxidation. Mass spectrometric measurements of single- and double-labeled dioxygen species after various incubation times of PSII with H218O provide insight into the substrate binding modes and sites via determination of exchange rates. Such experiments have revealed that the two substrate waters exchange with different rates that vary independently with the Si state and are hence referred to as the fast (Wf) and the slow (WS) substrate waters. New insight for the molecular interpretation of these rates arises from our recent finding that in the S2 state, under special experimental conditions, two different rates of WS exchange are observed that appear to correlate with the high spin and low spin conformations of the Mn4CaO5 cluster. Here, we reexamine and unite various proposed methods for extracting and assigning rate constants from this recent data set. The analysis results in a molecular model for substrate-water binding and exchange that reconciles the expected non-exchangeability of the central oxo bridge O5 when located between two Mn(IV) ions with the experimental and theoretical assignment of O5 as WS in all S states. The analysis also excludes other published proposals for explaining the water exchange kinetics.
Systematic inspection on the interplay between MoNa-induced sodium and the formation of MoSe2 intermediate layer in CIGSe/Mo heterostructures
Authors: Za’abar Fazliyana ‘Izzati , Doroody Camellia , Soudagar Manzoore Elahi Mohammad , Chelvanathan Puvaneswaran , Abdullah Wan Syakirah Wan , Zuhd Ahmad Wafi Mahmood , Cuce Erdem , Saboor Shaik 
Published: March 2024

AbstractThe critical impact of sodium-doped molybdenum (MoNa) in shaping the MoSe2 interfacial layer, influencing the electrical properties of CIGSe/Mo heterostructures, and achieving optimal MoSe2 formation conditions, leading to improved hetero-contact quality. Notably, samples with a 600-nm-thick MoNa layer demonstrate the highest resistivity (73 μΩcm) and sheet resistance (0.45 Ω/square), highlighting the substantial impact of MoNa layer thickness on electrical conductivity. Controlled sodium diffusion through MoNa layers is essential for achieving desirable electrical characteristics, influencing Na diffusion rates, grain sizes, and overall morphology, as elucidated by EDX and FESEM analyses. Additionally, XRD results provide insights into the spontaneous peeling-off phenomenon, with the sample featuring a ~ 600-nm MoNa layer displaying the strongest diffraction peak and the largest crystal size, indicative of enhanced Mo to MoSe2 conversion facilitated by sodium presence. Raman spectra further confirm the presence of MoSe2, with its thickness correlating with MoNa layer thickness. The observed increase in resistance and decrease in conductivity with rising MoSe2 layer thickness underscore the critical importance of optimal MoSe2 formation for transitioning from Schottky to ohmic contact in CIGSe/Mo heterostructures. Ultimately, significant factors to the advancement of CIGSe thin-film solar cell production are discussed, providing nuanced insights into the interplay of MoNa and MoSe2, elucidating their collective impact on the electrical characteristics of CIGSe/Mo heterostructures.
Graphical Abstract
NIAID/SMB Workshop on Multiscale Modeling of Infectious and Immune-Mediated Diseases
Authors: Shabman Reed S. , Craig Morgan , Laubenbacher Reinhard , Reeves Daniel , Brown Liliana L. 
Published: March 2024

AbstractOn July 19th, 2023, the National Institute of Allergy and Infectious Diseases co-organized a workshop with the Society of Mathematical Biology, with the authors of this paper as the organizing committee. The workshop, “Bridging multiscale modeling and practical clinical applications in infectious diseases” sought to create an environment for mathematical modelers, statisticians, and infectious disease researchers and clinicians to exchange ideas and perspectives.
Locoregional staging of breast cancer: contrast-enhanced mammography versus breast magnetic resonance imaging
Authors: Terzoni Andrea , Basile Paola , Gambaro Anna Clelia , Attanasio Silvia , Rampi Anna Maria , Brambilla Marco , Carriero Alessandro 
Published: March 2024

Abstract
Purpose
Breast cancer diagnosis often involves assessing the locoregional spread of the disease through MRI, as multicentricity, multifocality and/or bilaterality are increasingly common. Contrast-enhanced mammography (CEM) is emerging as a potential alternative method. This study compares the performance of CEM and MRI in preoperative staging of women with confirmed breast carcinoma. Patients were also asked to fill in a satisfaction questionnaire to rate their comfort level with each investigation.

Methods
From May 1st, 2021 to May 1st, 2022, we enrolled 70 women with confirmed breast carcinoma who were candidates for surgery. For pre-operative locoregional staging, all patients underwent CEM and MRI examination, which two radiologists evaluated blindly. We further investigated all suspicious locations for disease spread, identified by both CEM and MRI, with a second-look ultrasound (US) and eventual histological examination.

Results
In our study cohort, MRI and CEM identified 114 and 102 areas of focal contrast enhancement, respectively. A true discrepancy between MRI and CEM occurred in 9 out of 70 patients examined. MRI reported 8 additional lesions that proved to be false positives on second-look US in 6 patients, while it identified 4 lesions that were not detected by CEM and were pathological (true positives) in 3 patients.

Conclusions
CEM showed results comparable to MRI in the staging of breast cancer in our study population, with a high rate of patient acceptability.
Kinder- und Jugendpartizipation aus der Sicht von Bildungsakteur:innen
Authors: Zimmer Nils , Kolleck Nina 
Published: March 2024

ZusammenfassungDie Umsetzung von Partizipationsmöglichkeiten für Kinder- und Jugendliche im außerschulischen Bildungsbereich hängt in relevantem Maße von den Bestrebungen erwachsener Akteur:innen ab. Ausgehend von dieser Annahme beschäftigen wir uns im vorliegenden Beitrag mit der Frage, welche Partizipationsverständnisse von Bildungsakteur:innen vertreten werden. Zu diesem Zwecke führten wir 18 Interviews mit Akteur:innen aus insgesamt vier Kommunen. Sie alle gehörten zum Zeitpunkt der Erhebung kommunalen Netzwerken an, deren Ziel der Auf- und Ausbau kultureller Bildungsangebote für Kinder und Jugendliche ist. Der theoretische Rahmen des Beitrags speist sich aus der Auseinandersetzung mit einem Partizipationsmodell, das sich mit der Rolle Erwachsener im Partizipationsprozess junger Menschen und den damit verbundenen Auswirkungen unterschiedlicher Formen der Beteiligung beschäftigt. Die Auswertung der Interviews folgte einer strukturierenden qualitativen Inhaltsanalyse. Daran anknüpfend identifizierten wir drei Typen von Akteur:innen, die wir Idealist:in, Pragmatiker:in und Skeptiker:in nennen. Diese stellen wir im Ergebnisteil unseres Beitrags vor. Abschließend diskutieren wir die Ergebnisse unserer Untersuchung hinsichtlich der Erkenntnisse sowie in Bezug auf den aktuellen Forschungsstand, den theoretischen Rahmen der Untersuchung und die Wahl der Methode.
Comparison of Dynamic Measures in Intraoperative Goal-Directed Fluid Therapy of Patients with Morbid Obesity Undergoing Laparoscopic Sleeve Gastrectomy
Authors: Urhan Gökhan , Demirel İsmail , Deniz Ahmet , Aksu Ahmet , Altun Aysun Yıldız , Bolat Esef , Beştaş Azize , Altuntaş Gülsüm 
Published: March 2024

Abstract
Introduction
Obesity increases the risk of morbidity and mortality during surgical procedures. Goal-directed fluid therapy (GDFT) is a new concept for perioperative fluid management that has been shown to improve patient prognosis. This study aimed to investigate the role of the Pleth Variability Index (PVI), systolic pressure variation (SPV), and pulse pressure variation (PPV) in maintaining tissue perfusion and renal function during GDFT management in patients undergoing laparoscopic sleeve gastrectomy (LSG).

Materials and Methods
Two hundred ten patients were enrolled in our prospective randomized controlled clinical trial. Demographic data, hemodynamic parameters, biochemical parameters, the amount of crystalloid and colloid fluid administered intraoperatively, and the technique of goal-directed fluid management used were recorded. Patients were randomly divided into three groups: PVI (n = 70), PPV (n = 70), and SPV (n = 70), according to the technique of goal-directed fluid management. Postoperative nausea and vomiting, time of return of bowel movement, and hospital stay duration were recorded.

Results
There was no statistically significant difference between the number of crystalloids administered in all three groups. However, the amount of colloid administered was statistically significantly lower in the SPV group than in the PVI group, and there was no significant difference in the other groups. Statistically, there was no significant difference between the groups in plasma lactate, blood urea, and creatinine levels.

Conclusion
In LSG, dynamic measurement techniques such as PVI, SPV, and PPV can be used in patients with morbid obesity without causing intraoperative and postoperative complications. PVI may be preferred over other invasive methods because it is noninvasive.

Graphical abstract
A Cost Effective Solution to an Automated Valet Parking System
Authors: Dönmez Ömer , Vaculín Ondřej , de Borba Thiago 
Published: March 2024

AbstractAutomated Valet Parking Systems (AVPS) relieve the driver of the entire parking process. Many of the systems known today rely on a combination of automotive sensors with sensors of the infrastructure. For this purpose, parking facilities are equipped with comprehensive sensor technology to support the vehicles in environment sensing and route planning. This approach is comparatively expensive which is why many parking operators don’t provide that technology to their customers. This paper proposes a lean AVPS system architecture that requires minimal effort to adapt the infrastructure. At the same time, state-of-the-art vehicle technology is used to make AVPS more profitable overall. At the beginning, an overview will be given describing the state of the art of AVPS. Subsequently, requirements for the AVPS will be elaborated, whereby the system can be designed and implemented in the following. Finally, the presentation of simulation results shows that one doesn’t have to extend the infrastructure with sensors to develop a safe and reliable AVPS.
Genetically driven predisposition leads to an unusually genomic unstable renal cell carcinoma
Authors: Scimeca Manuel , Rovella Valentina , Caporali Sabrina , Shi Yufang , Bischof Julia , Woodsmith Jonathan , Tisone Giuseppe , Sica Giuseppe , Amelio Ivano , Melino Gerry , Mauriello Alessandro , Bove Pierluigi 
Published: March 2024

AbstractRenal cell carcinoma originates from the lining of the proximal convoluted renal tubule and represents the most common type of kidney cancer. Risk factors and comorbidities might be associated to renal cell carcinoma, while a small fraction of 2–3% emerges from patients with predisposing cancer syndromes, typically associated to hereditary mutations in VHL, folliculin, fumarate hydratase or MET genes. Here, we report a case of renal cell carcinoma in patient with concurrent germline mutations in BRCA1 and RAD51 genes. This case displays an unusual high mutational burden and chromosomal aberrations compared to the typical profile of renal cell carcinoma. Mutational analysis on whole genome sequencing revealed an enrichment of the MMR2 mutational signature, which is indicative of impaired DNA repair capacity. Overall, the tumor displayed a profile of unusual high genomic instability which suggests a possible origin from germline predisposing mutations in the DNA repair genes BRCA1 and RAD51. While BRCA1 and RAD51 germline mutations are well-characterised in breast and ovarian cancer, their role in renal cell carcinoma is still largely unexplored. The genomic instability detected in this case of renal cell carcinoma, along with the presence of unusual mutations, might offer support to clinicians for the development of patient-tailored therapies.
‘I want to make a difference’: Students co-researching school cultures of gender and sexuality
Authors: Rawlings Victoria 
Published: March 2024

AbstractResearch on violence in schools has been dominated by ‘bullying’ discourse and methodologies that place individualised pathos at the centre of problematic behaviours. This focus has resulted in the neglect of broader structures of power such as gender, sexuality, race, ethnicity, and class in the violence enacted and encountered by young people. As a result, institutional solutions to school violence have often failed to acknowledge and respond to the ways that gender and sexuality might operate in the lives of young people, instead offering simplistic strategies to reduce ubiquitous forms of ‘bullying’. Simultaneously, political discourses and research challenges further prohibit young people from contributing to targeted and critical interventions into the socio-cultural practices of gender- and sexuality-making in schools. As outsiders to these nuanced, complex, and dynamic spaces, university-based researchers often lack vocabulary and literacy, especially in relation to always-shifting meanings around gender and sexuality. In this paper, I argue for the need to actively include young people in research praxis to co-investigate school cultures of gender and sexuality using a Community-Led Research (CLR) approach. Reporting on work with ten student co-researchers that formed two groups in two schools in Australia, the paper details some of the ways that they impacted and benefitted the early phases of a three-year project, including through impacting methods, participant engagement, data analysis and the implementation of new strategies to improve school cultures of gender and sexuality. This article also illustrates some of the challenges and opportunities that CLR methodologies produce when working in less structured settings, including ethical and social challenges that emerge in iterative research praxis. Findings argue for the rights of young people to exert their hopes for their school cultures that relate to gender and sexuality, particularly through research-based empowerment. While often slower and more difficult, co-researching with young people can produce opportunities for transformation and change not only of research processes, but also of researchers and their communities.
Potential Micronutrient Deficiencies in the First 1000 Days of Life: The Pediatrician on the Side of the Weakest
Authors: Panzeri Carolà , Pecoraro Luca , Dianin Alice , Sboarina Andrea , Arnone Olivia C. , Piacentini Giorgio , Pietrobelli Angelo 
Published: March 2024

Abstract
Purpose of Review
This study is to examine potential micronutrient deficiencies and any need for supplementation in children following specific diet plans in the first 1000 days of life.

Recent Findings
Optimal nutrition in the first 1000 days of life has a lifelong positive impact on child development. Specific intrauterine and perinatal factors, pathological conditions, and dietary restrictions can represent potential risk factors for micronutrient deficiencies in the first 1000 days of life, which can have negative systemic consequences. Preterm and low-birth-weight infants are intrinsically at risk because of immature body systems. Children affected by cystic fibrosis are prone to malnutrition because of intestinal malabsorption. The risk of micronutrient deficiency can increase in various situations, including but not limited to children following selective dietary regimens (vegetarian and vegan diets and children affected by specific neuropsychiatric conditions) or specific dietary therapies (children affected by food allergies or specific metabolic disorders and children following restricted diet as a part of therapeutic approach, i.e., ketogenic diet for epilepsy). In light of this situation, the micronutrient status in these categories of children should be investigated in order to tailor strategies specific to the individual’s metabolic needs, with a particular focus on deficiencies which can impair or delay the physical and cognitive development of children, namely, vitamin B12, vitamin D and folic acid, as well as oligo-elements such as iron, zinc, calcium, sodium, magnesium, and phosphorus, and essential fatty acids such as omega-3.

Summary
Identification of micronutrient deficiency in the first 1000 days of life and timely supplementation proves essential to prevent their long-term consequences.

Graphical Abstract
Normativity, Autonomy, and Agency: A Critical Review of Three Essays on Agency in Nature, and a Modest Proposal for the Road Ahead
Authors: Moss Lenny 
Published: March 2024

AbstractHas the renewal of interest in the ostensible agency of living beings signaled an advance from a merely heuristic Kantian sense of purposiveness to an unequivocally, empirically grounded research program or are there as yet hidden tensions or contradictions in, for example, the organizational autonomy approach to natural agency? Can normativity be found to be immanent in nature but only beginning with the living cell or must a thoroughgoing naturalism find the seeds of normativity immanent throughout abiotic as well as biotic nature? Beginning with a brief exposition of Kant´s influential treatment and recommendation for how to methodologically combine what he took to be the inevitable epistemological limit to explaining the origins of ostensible biotic purposefulness with the legitimate intentions of scientific research and explanation, this essay will critically engage with three recent essays that attempt to grapple with the preceding questions. Having putatively raised questions about the consistency and adequacy of each of the individual positions, the essay will attempt to move synthetically, drawing upon aspects of all three contributions, in the direction of a “cooperativity theoretic” approach to incipient natural normativity and agency.