bluuebunny/crossref_metadata_2025_split huggingface dataset:
Reubicación De Introductores Mayoristas De La Via Pública Del Canton La Libertad Añ0 2024
Authors: Romo Pezantes Gabriel David 
Published: February 2025

La actividad de los introductores mayoristas en la vía pública ha generado una serie de desafíos interrelacionados que afectan el desarrollo urbano, económico y social de la localidad. Estas actividades, que proveen productos al mercado central y a los mercados particulares Feria Libre y Unidos Venceremos, están marcadas por prácticas informales que generan impactos negativos en varios niveles. Desde un enfoque socioeconómico, los mayoristas no cuentan con una estructura que regule sus actividades, lo que resulta en la evasión de impuestos municipales. Esto limita la capacidad financiera del municipio para implementar políticas de desarrollo y ordenamiento. Además, la carencia de una infraestructura adecuada para llevar a cabo estas actividades. agrava el problema, perpetuando prácticas informales que afectan tanto a los comerciantes formales como a los ciudadanos. La reubicación pretende tres escenarios nuevos, la recuperación del espacio, la seguridad y la salubridad. Por lo tanto, es crucial desarrollar un plan de reubicación que no solo priorice el ordenamiento del espacio público, sino que le devuelva una imagen renovada a la ciudad, lo que implica niveles de seguridad colectiva. La metodología empleada se centrará en un enfoque mixto, combinando técnicas cualitativas y cuantitativas. Se realizarán encuestas y entrevistas a los introductores mayoristas y a autoridades locales para comprender las condiciones actuales y las percepciones sobre la reubicación. Asimismo, se realizaron análisis geoespaciales para identificar las zonas más adecuadas para las nuevas ubicaciones. Los principales resultados esperados incluyen la identificación de las áreas de mayor viabilidad para la reubicación, la mejora en las condiciones de trabajo para los introductores y un impacto positivo en el orden del cantón.
Antimicrobial Resistance Pattern of Some Microorganisms Isolated from Packaged Food Samples
Authors: Israel OMOMOWO, Olawale , Kola ABDULKADIR, Arasim , Olunike OMOMOWO, Iyabo , Ayobami AMAO, John , Omotola OMOTOSO, Ifeoluwa 
Published: February 2025

Aims: The aim of this study was to determine the presence of microorganisms in packaged foods which are very popular among the elites, who may assume that these foods will be totally save, especially for their children; and determine the resistance pattern of microorganisms isolated from these selected packaged food samples.
Study Design: The study employed an experimental study design.
Place and Duration of Study: Samples were collected between March and May, 2021 and the study spanned from January 2021 to April 2022. The research was carried out in the Microbiology Laboratory of Pure and Applied Biology Departement, Ladoke Akintola University of Technology, Ogbomoso, Oyo State, Nigeria.
Methodology: Isolation of microorganisms were done by standard microbiological methods. The abilities of bacteria isolates to produce biofilm were determined and quantified at 492 nm with HALOMPR-96 visible microplate reader. Bacteria and fungi isolates were tested for their sensitivity to antimicrobials with different antibacterial and antifungal disc and results compared with guidelines from Clinical and Laboratory Standard Institute (CLSI, 2018). Selected bacteria and fungi isolates were characterized molecularly by 16S rRNA and ITS respectively.
Results: A total of 17 bacteria and 13 fungi isolated from sampled packaged food belonging to 6 bacteria genera and 4 fungi genera respectively were obtained. All bacteria isolates were either moderate or weak biofilm producers. A 100 % sensitivity to Gentamicin and Ofloxacin was observed among Gram positive bacteria. All fungi isolates were sensitive to one or more of the antifungal used. Molecular identity of selected bacteria and fungi isolates revealed their closest isolates from available isolates in GenBank.
Conclusion: Packaged foods are important source of microorganisms that can be of public health importance. Ingestion of contaminated food products can lead to food poisoning. The resistance of these microbes to antibiotics makes such a difficult situation to handle.
Access to Specialty Care for Commercially Insured Youths With Type 1 and Type 2 Diabetes
Authors: March Christine A. , Byerly Amy R. , Siminerio Linda , Miller Elizabeth , Rothenberger Scott , Libman Ingrid 
Published: April 2024

ImportanceYouths with type 2 diabetes are at higher risk for complications compared with peers with type 1 diabetes, though few studies have evaluated differences in access to specialty care.ObjectiveTo compare claims with diabetes specialists for youths with type 1 vs type 2 diabetes and the association between specialist claims with multidisciplinary and acute care utilization.Design, Setting, and ParticipantsThis cross-sectional study used Optum Clinformatics Data Mart commercial claims. Individuals included in the study were youths younger than 19 years with type 1 or 2 diabetes as determined by a validated algorithm and prescription claims. Data were collected for youths with at least 80% enrollment in a commercial health plan from December 1, 2018, to December 31, 2019. Statistical analysis was performed from September 2022 to January 2024.Main Outcomes and MeasuresThe primary outcome was the number of ambulatory claims from an endocrine and/or diabetes physician or advanced practice clinician associated with a diabetes diagnosis code; secondary outcomes included multidisciplinary and acute care claims.ResultsClaims were analyzed for 4772 youths (mean [SD] age, 13.6 [3.7] years; 4300 [90.1%] type 1 diabetes; 472 [9.9%] type 2 diabetes; 2465 [51.7%] male; 128 [2.7%] Asian, 303 [6.4] Black or African American, 429 [9.0%] Hispanic or Latino, 3366 [70.5%] non-Hispanic White, and 546 [11.4%] unknown race and ethnicity). Specialist claims were lower in type 2 compared with type 1 diabetes (incidence rate ratio [IRR], 0.61 [95% CI, 0.52-0.72]; P &amp;lt; .001) in propensity score–weighted analyses. The presence of a comorbidity was associated with increased specialist claims for type 1 diabetes (IRR, 1.07 [95% CI, 1.03-1.10]) and decreased claims for type 2 diabetes (IRR, 0.77 [95% CI, 0.67-0.87]). Pooling diagnosis groups and adjusted for covariates, each additional specialist claim was associated with increased odds of a claim with a diabetes care and education specialist (odds ratio [OR], 1.31 [95% CI, 1.25-1.36]), dietitian (OR, 1.14 [95% CI, 1.09-1.19]), and behavioral health clinician (OR, 1.16 [95% CI, 1.12-1.20]). For acute care claims, each additional specialist claim was associated with increased odds of admission (OR, 1.17 [95% CI, 1.11-1.24]) but not for emergency claims (OR, 1.03 [95% CI, 0.98-1.82]).Conclusions and RelevanceThis cross-sectional study found that youths with type 2 diabetes were significantly less likely to have specialist claims despite insurance coverage, indicating other barriers to care, which may include medical complexity. Access to diabetes specialists influences engagement with multidisciplinary services. The association between increasing ambulatory clinician services and admissions suggests high utilization by a subgroup of patients at greater risk for poor outcomes.
Correlation between spatial characteristics and overflow rate of back alleys in high‐density city of Hong Kong
Authors: Du Da , Gao Yuhan , Zhang Wenda , Wang Xinpeng , Furuya Nobuaki 
Published: April 2024

AbstractIn recent years, scholarly attention has shifted within urban informality research from informal settlements to the appropriation of public spaces in formal urban settings. Overflow, a common research subject within this context, has drawn particular interest. This study investigates overflow dynamics in a representative district of Hong Kong, utilizing the overflow rate as a measure of the extent to which overflow occurs. Three‐dimensional (3D) scanning technology was applied to collect spatial data from back alleys. Multiple linear regression analyses were conducted to identify the spatial characteristics of back alleys that influence overflow rates. The results revealed that back alleys with a flatter spatial interface, more overhead shelter, greater numbers of alley‐shops, and shorter overall length corresponded to a higher number of overflow occurrences. Two novel findings emerged: First, a negative correlation between spatial interface unevenness and overflow rates, and second, differential impacts of the shop density and number of alley‐shops on overflow rates. These findings may serve as a valuable reference for governmental policy formulation regarding overflow management and may offer architects workable insights for designing back alleys and street spaces conducive to public use.
Electrocatalytic Conversion of Nitrate Into Ammonia Through Heterogeneous Catalysis of NiMoO4 and Cu/Cu2O
Authors: Lin Changzheng , Chen Xin , Wang Ling , Li Weijia , Wang Zhenyu , Li Mingtao , Feng Jiangtao , Hou Bo , Yan Wei 
Published: April 2024

AbstractFacilitating equilibrium in the nitrogen cycle, electrochemical nitrate reduction (NitRR) to ammonia stands as a carbon‐free method for ammonia synthesis. Copper‐based catalysts, renowned for NitRR, face a hurdle in supplying sufficient hydrogen radicals (*H) for efficient hydrogenation of NitRR intermediates. Addressing this, NiMoO4 is leveraged as an excellent *H donor, synergistically coupling it with a copper‐based catalyst. The work introduces a high‐performance NiMoO4/CuO nanowire (NW)/Copper foam (CF) catalyst for NitRR, achieving a remarkable Faraday efficiency (FE) of 98.8% and a yield of 0.8221 mmol cm−2 h−1. Operating at −0.2 V versus reversible hydrogen electrode (vs RHE) in an H‐type electrolytic cell, the catalyst demonstrates exceptional stability over 20 h. Additionally, coupling NitRR with an air stripping process enables efficient collection of NH4Cl products, offering a practical avenue for converting waste nitrates into valuable ammonia products. In‐depth in situ electrochemistry and density‐functional theory (DFT) calculations affirm the transformation of CuO into Cu/Cu2O during the electrocatalytic reduction process. Cu/Cu2O catalyzes nitrate conversion to nitrite, while NiMoO4, serving as a *H donor, facilitates deoxidation and hydrogenation of other N intermediates on the Cu/Cu2O surface, effectively driving the reduction of nitrate to ammonia.
Investigation of the Dysfunction Caused by High Glucose, Advanced Glycation End Products, and Interleukin‐1 Beta and the Effects of Therapeutic Agents on the Microphysiological Artery Model
Authors: Nam Ungsig , Kim Jaesang , Yi Hee‐gyeong , Jeon Jessie S. 
Published: April 2024

AbstractDiabetes mellitus (DM) has substantial global implications and contributes to vascular inflammation and the onset of atherosclerotic cardiovascular diseases. However, translating the findings from animal models to humans has inherent limitations, necessitating a novel platform. Therefore, herein, an arterial model is established using a microphysiological system. This model successfully replicates the stratified characteristics of human arteries by integrating collagen, endothelial cells (ECs), and vascular smooth muscle cells (VSMCs). Perfusion via a peristaltic pump shows dynamic characteristics distinct from those of static culture models. High glucose, advanced glycation end products (AGEs), and interleukin‐1 beta are employed to stimulate diabetic conditions, resulting in notable cellular changes and different levels of cytokines and nitric oxide. Additionally, the interactions between the disease models and oxidized low‐density lipoproteins (LDL) are examined. Finally, the potential therapeutic effects of metformin, atorvastatin, and diphenyleneiodonium are investigated. Metformin and diphenyleneiodonium mitigate high‐glucose‐ and AGE‐associated pathological changes, whereas atorvastatin affects only the morphology of ECs. Altogether, the arterial model represents a pivotal advancement, offering a robust and insightful platform for investigating cardiovascular diseases and their corresponding drug development.
Overcoming the Incompatibility Between Electrical Conductivity and Electromagnetic Transmissivity: A Graphene Glass Fiber Fabric Design Strategy
Authors: Huang Kewen , Liang Fushun , Sun Jianbo , Zhang Qinchi , Li Zhihao , Cheng Shuting , Li Wenjuan , Yuan Hao , Liu Ruojuan , Ge Yunsong , Cheng Yi , Wang Kun , Jiang Jun , Yang Yuyao , Ma Mingyang , Yang Fan , Tu Ce , Xie Qin , Yin Wanjian , Wang Xiaobai , Qi Yue , Liu Zhongfan 
Published: April 2024

AbstractConventional conductive materials such as metals are crucial functional components of conductive systems in diverse electronic instruments. However, their severe intrinsic impedance mismatch with air dielectric causes strong reflection of incident electromagnetic waves, and the resulting low electromagnetic transmissivity typically interferes with surrounding electromagnetic signal communications in modern multifunction‐integrated instruments. Herein, graphene glass fiber fabric (GGFF) that merges intrinsic electrical and electromagnetic properties of graphene with dielectric attributes and highly porous macrostructure of glass fiber fabric (GFF) is innovatively developed. Using a novel decoupling chemical vapor deposition growth strategy, high‐quality and layer‐limited graphene is prepared on noncatalytic nonmetallic GFF in a controlled manner; this is pivotal to realizing GGFF with the desired compatibility among high conductivity, low electromagnetic reflectivity, and high electromagnetic transmissivity. At the same sheet resistance over a wide range of values (250–3000 Ω·sq−1), the GGFF exhibits significantly lower electromagnetic reflectivity (by 0.42–0.51) and higher transmissivity (by 0.27–0.62) than those of its metal‐based conductive counterpart (CuGFF). The material design strategy reported herein provides a constructive solution to eliminate the incompatibility between electrical conductivity and electromagnetic transmissivity faced by conventional conductive materials, spotlighting the applicability of GGFF in electric heating scenarios in radar, antenna, and stealth systems.
Mechanisms of the Accelerated Li+ Conduction in MOF‐Based Solid‐State Polymer Electrolytes for All‐Solid‐State Lithium Metal Batteries
Authors: Duan Song , Qian Lanting , Zheng Yun , Zhu Yanfei , Liu Xiang , Dong Li , Yan Wei , Zhang Jiujun 
Published: April 2024

AbstractSolid polymer electrolytes (SPEs) for lithium metal batteries have garnered considerable interests owing to their low cost, flexibility, lightweight, and favorable interfacial compatibility with battery electrodes. Their soft mechanical nature compared to solid inorganic electrolytes give them a large advantage to be used in low pressure solid‐state lithium metal batteries, which can avoid the cost and weight of the pressure cages. However, the application of SPEs is hindered by their relatively low ionic conductivity. In addressing this limitation, enormous efforts are devoted to the experimental investigation and theoretical calculations/simulation of new polymer classes. Recently, metal–organic frameworks (MOFs) have been shown to be effective in enhancing ion transport in SPEs. However, the mechanisms in enhancing Li+ conductivity have rarely been systematically and comprehensively analyzed. Therefore, this review provides an in‐depth summary of the mechanisms of MOF‐enhanced Li+ transport in MOF‐based solid polymer electrolytes (MSPEs) in terms of polymer, MOF, MOF/polymer interface, and solid electrolyte interface aspects, respectively. Moreover, the understanding of Li+ conduction mechanisms through employing advanced characterization tools, theoretical calculations, and simulations are also reviewed in this review. Finally, the main challenges in developing MSPEs are deeply analyzed and the corresponding future research directions are also proposed.
Guest Acceptors with Lower Electrostatic Potential in Ternary Organic Solar Cells for Minimizing Voltage Losses
Authors: Yang Shuncheng , Chen Zhenyu , Zhu Jintao , Yang Daobin , Wang Hongqian , Ding Pengfei , Wu Jie , Yan Pengyu , Xie Lin , Chen Fei , Wang Yuming , Zhang Jianqi , Ge Ziyi 
Published: April 2024

AbstractThe ternary strategy, in which one guest component is introduced into one host binary system, is considered to be one of the most effective ways to realize high‐efficiency organic solar cells (OSCs). To date, there is no efficient method to predict the effectiveness of guest components in ternary OSCs. Herein, three guest compositions (i.e., ANF‐1, ANF‐2 and ANF‐3) with different electrostatic potential (ESP) are designed and synthesized by modulating the electron‐withdrawing ability of the terminal groups through density functional theory simulations. The effects of the introduction of guest component into the host system (D18:N3) on the photovoltaic properties are investigated. The theoretical and experimental studies provide a key rule for guest acceptor in ternary OSCs to improve the open‐circuit voltage, that is, the larger ESP difference between the guest and host acceptor, the stronger the intermolecular interactions and the higher the miscibility, which improves the luminescent efficiency of the blend film and the electroluminescence quantum yield (EQEEL) of the device by reducing the aggregation‐caused‐quenching, thereby effectively decreasing the non‐radiative voltage loss of ternary OSCs. This work will greatly contribute to the development of highly efficient guest components, thereby promoting the rapid breakthrough of the 20% efficiency bottleneck for single‐junction OSCs.
Gradient OH Desorption Facilitating Alkaline Hydrogen Evolution Over Ultrafine Quinary Nanoalloy
Authors: Ren Hao , Zhang Zhihao , Geng Zhanxin , Wang Zhe , Shen Fengyi , Liang Xinhu , Cai Zengjian , Wang Yufang , Cheng Dan , Cao Yanan , Yang Xiaoxin , Hu Mingzhen , Yao Xin , Zhou Kebin 
Published: April 2024

AbstractStrengthening OH adsorption on electrocatalyst is crucial to promote the rate‐determining water dissociation step of alkaline hydrogen evolution reaction (HER), whereas too‐intensified OH adsorption will poison the active sites instead. This dilemma remains one of the major challenges for improving the electrocatalysts’ alkaline HER activities. Herein, a surprising finding that the strongly adsorbed OH on an ultrafine quinary PtCoCuNiZn nanoalloy can be facilely desorbed via a unique gradient OH desorption pattern is reported, which tremendously boosts its alkaline HER activity. Theoretical simulations unravel that the ultrafine PtCoCuNiZn nanoalloy possesses versatile metal sites for adsorbing OH and the strongly adsorbed OH can be gradiently transferred to desorb from the ultrafine PtCoCuNiZn nanoalloy with moderate energy barriers for each transfer step that is the gradient OH desorption. In the meanwhile, the unique gradient OH desorption mode on the ultrafine PtCoCuNiZn nanoalloy is also experimentally evidenced by the in situ Raman spectroscopy and cyclic voltammetry measurements. This finding offers a fresh opportunity to expedite the alkaline HER without compromising the OH adsorption strength on electrocatalysts, which thus maximally promotes their water dissociation properties and unlocks the full potential of their alkaline HER activities.
Methyl‐ and Methoxy‐substituted 2‐(Pyridin‐2‐yl)‐4‐(4‐aminophenyl)quinazolines: Synthesis and Photophysical Properties
Authors: Kopotilova Alexandra E. , Valieva Maria I. , Kudryashova Ekaterina A. , Starnovskaya Ekaterina S. , Moshkina Tatyana N. , Nosova Emiliya V. , Taniya Olga S. , Kalinichev Alexey A. , Novikov Alexander S. , Kopchuk Dmitry S. , Slepukhin Pavel A. , Charushin Valery N. 
Published: April 2024

AbstractA series of novel 2‐(2‐pyridyl)quinazoline luminophores containing a donor aryl fragment at position 4 and methyl or methoxy groups at benzene ring has been synthesized by efficient three‐step route. The linear optical properties have been studied by UV/Vis absorption and photoluminescence spectra in two solvents. We revealed that introduction of additional methyl group or the replacement of methyl substituents with methoxy ones lead to sequentially shift of absorption and emission maximum to blue region. 9H‐Carbazol‐9‐yl‐containing derivative is characterized by hypsochromically shifted absorption band compared to its NEt2 and NPh2 counterparts. Unlike 9H‐carbazol‐9‐yl‐derivative, Et2N‐ and Ph2N‐bearing quinazolines demonstrate considerable decrease in quantum yield values when going from toluene to MeCN. Solvatochromic properties have been explored, the pronounced bathochromic shift was observed in fluorescence spectra with the increase of solvents polarity. Moreover, the compounds show significant shift of emission band with the increase of water fraction in DMSO/H2O mixture. Two‐photon optical properties have been also studied, the two‐photon absorption cross‐sections in MeCN and toluene reached 120 GM and 210 GM, respectively. The presence of additional methyl group has little impact on δTPA value, while introduction of methoxy substituents dramatically decreases TPA cross sections. Additionally, a quantum‐chemical calculations of synthesized compounds were performed to support the experimental data.
Blood‐Based Proteomics for Adult‐Onset Focal Dystonias
Authors: Timsina Jigyasha , Dinasarapu Ashok , Kilic‐Berkmen Gamze , Budde John , Sung Yun Ju , Klein Adam M. , Cruchaga Carlos , Jinnah H. A. 
Published: April 2024

ObjectivesThe adult‐onset focal dystonias are characterized by over‐active muscles leading to abnormal movements. For most cases, the etiology and pathogenesis remain unknown. In the current study, unbiased proteomics methods were used to identify potential changes in blood plasma proteins.MethodsA large‐scale unbiased proteomics screen was used to compare proteins (N = 6,345) in blood plasma of normal healthy controls (N = 49) with adult‐onset focal dystonia (N = 143) consisting of specific subpopulations of cervical dystonia (N = 45), laryngeal dystonia (N = 49), and blepharospasm (N = 49). Pathway analyses were conducted to identify relevant biological pathways. Finally, protein changes were used to build a prediction model for dystonia.ResultsAfter correction for multiple comparisons, 15 proteins were associated with adult‐onset focal dystonia. Subgroup analyses revealed some proteins were shared across the dystonia subgroups while others were unique to 1 subgroup. The top biological pathways involved changes in the immune system, metal ion transport, and reactive oxygen species. A 4‐protein model showed high accuracy in discriminating control individuals from dystonia cases [average area under the curve (AUC) = 0.89].InterpretationThese studies provide novel insights into the etiopathogenesis of dystonia, as well as novel potential biomarkers. ANN NEUROL 2024;96:110–120