bluuebunny/crossref_metadata_2025_split huggingface dataset:
What Is Existence?
Authors: Cottingham John 
Published: February 2024

AbstractThis paper argues that being there, actually existing, is a notion that cannot be explicated by formal logicians, cannot be defined in terms of conscious perception, and cannot be satisfactorily explained using the theories of mathematics or natural science. So, must we turn to theology to make up for the deficiencies of the methods so far canvassed? The paper concludes by considering the Thomistic identification of God with existence itself, but argues that it would be a mistake to suppose that the mystery of actual existence is thereby dispelled.
Tropical vegetation productivity and atmospheric methane over the last 40,000 years from model simulations and stalagmites in Sulawesi, Indonesia
Authors: Krause Claire E. , Kimbrough Alena K. , Gagan Michael K. , Hopcroft Peter O. , Dunbar Gavin B. , Hantoro Wahyoe S. , Hellstrom John C. , Cheng Hai , Edwards R. Lawrence , Wong Henri , Suwargadi Bambang W. , Valdes Paul J. , Rifai Hamdi 
Published: February 2024

AbstractRecent research has shown the potential of speleothem δ13C to record a range of environmental processes. Here, we report on 230Th-dated stalagmite δ13C records for southwest Sulawesi, Indonesia, over the last 40,000 yr to investigate the relationship between tropical vegetation productivity and atmospheric methane concentrations. We demonstrate that the Sulawesi stalagmite δ13C record is driven by changes in vegetation productivity and soil respiration and explore the link between soil respiration and tropical methane emissions using HadCM3 and the Sheffield Dynamic Global Vegetation Model. The model indicates that changes in soil respiration are primarily driven by changes in temperature and CO2, in line with our interpretation of stalagmite δ13C. In turn, modelled methane emissions are driven by soil respiration, providing a mechanism that links methane to stalagmite δ13C. This relationship is particularly strong during the last glaciation, indicating a key role for the tropics in controlling atmospheric methane when emissions from high-latitude boreal wetlands were suppressed. With further investigation, the link between δ13C in stalagmites and tropical methane could provide a low-latitude proxy complementary to polar ice core records to improve our understanding of the glacial–interglacial methane budget.
Does sweetness exposure drive ‘sweet tooth’?
Authors: Mela David J. , Risso Davide 
Published: February 2024

AbstractIt is widely believed that exposure to sweetened foods and beverages stimulates the liking and desire for sweetness. Here we provide an updated review of the empirical evidence from human research examining whether exposure to sweet foods or beverages influences subsequent general liking for sweetness (‘sweet tooth’), based on the conclusions of existing systematic reviews and more recent research identified from a structured search of literature. Prior reviews have concluded that the evidence for a relationship between sweet taste exposure and measures of sweet taste liking is equivocal, and more recent primary research generally does not support the view that exposure drives increased liking for sweetness, in adults or children. In intervention trials using a range of designs, acute exposure to sweetness usually has the opposite effect (reducing subsequent liking and desire for sweet taste), while sustained exposures have no significant effects or inconsistent effects. Recent longitudinal observational studies in infants and children also report no significant associations between exposures to sweet foods and beverages with measures of sweet taste preferences. Overall, while it is widely assumed that exposure to sweetness stimulates a greater liking and desire for sweetness, this is not borne out by the balance of empirical evidence. While new research may provide a more robust evidence base, there are also a number of methodological, biological and behavioural considerations that may underpin the apparent absence of a positive relationship between sweetness exposure and liking.
Before Stockholm: Emotions and Victimhood in Mediterranean Kidnapping Narratives, 1866–1921
Authors: Hornung Juliane 
Published: February 2024

AbstractFifty years ago, the infamous bank robbery and ensuing hostage crisis that took place in a Stockholm bank gave rise to the so-called ‘Stockholm syndrome’. Though never recognized as a valid medical diagnosis, the (allegedly) pathological relationship between kidnapper and hostage has become an omnipresent media phenomenon that inspires movies and television series to this day. However, this forced bond was not always seen as problematic. The years between 1860 and 1910 witnessed the rise of kidnappings in the Mediterranean world (Southern Italy, Greece, the Ottoman Balkan region, and Morocco) involving English, American, and European hostages. Today, we know about these incidents from autobiographical narratives by the former captives. They painted a surprisingly favourable picture of their captors – and found enthusiastic audiences for their stories. Looking at the interplay of feelings, coercion, and empowerment, the article opens up a new perspective on the history of emotions that brings both victims and perpetrators into the picture.
The Interplay between Hereditary Traditional Leaders, Democratically Elected Leaders and Succession: A Case Study from Makapanstad, North West Province, South Africa
Authors: Manthwa Aubrey , Ntsoane Lefa 
Published: February 2024

AbstractThis article examines the interplay between traditional leaders, democratically elected leaders and succession in Makapanstad Village, North West Province, South Africa. The article stems from community-based participatory action research conducted in Makapanstad in 2018. The article uses research data, in the form of community dialogue, together with desktop literature on the same subject. The article analyses the significance and role of traditional leadership in a democratic South Africa. It considers traditional leadership and democratically elected leadership in conjunction with succession and the demarcation of roles and responsibilities. The article analyses participants’ views to explore the form of leadership preferred by the residents of Makapanstad. It argues that, despite the recognition of traditional leadership in South Africa's Constitution, the roles and responsibilities of traditional leaders in local and provincial arms of government are limited, in contrast to those of democratically elected leaders.
Longitudinal development of second language utterance fluency, cognitive fluency, and their relationship
Authors: Kahng Jimin 
Published: February 2024

AbstractThe development of L2 utterance fluency has been extensively researched, whereas that of cognitive fluency has rarely been examined. This study investigated the longitudinal development of L2 utterance and cognitive fluency and their relationship. Thirty-one Chinese learners of English completed speaking tasks and a set of tasks for cognitive fluency before and after 5 months’ study abroad. The results showed that participants made a significant improvement in mean syllable duration, end-clause pause frequency, and the speed of syntactic encoding and articulation but not in mid-clause pause frequency or lexical retrieval speed. Mixed-effects modeling confirmed a significant relationship between syntactic encoding speed and mean syllable duration and mid-clause pausing. Furthermore, the significant relationships were maintained over time. The findings highlight (a) the differences between mid-clause and end-clause pausing in terms of their developmental patterns and relationship with cognitive fluency and (b) a significant role of syntactic encoding speed in L2 utterance fluency.
Evolution of ice rises in the Fimbul Ice Shelf, Dronning Maud Land, over the last millennium
Authors: Goel Vikram , Martín Carlos , Matsuoka Kenichi 
Published: February 2024

AbstractWe investigate two ice rises, Kupol Moskovskij and Kupol Ciolkovskogo, in the Fimbul Ice Shelf, East Antarctica, situated ~60 km from each other but differing in their glaciological settings. We apply a thermo-mechanically coupled Elmer/Ice model to profiles going across these ice rises and use it to investigate their past evolution covering present to several millennia ago. We constrain the model results using field measurements, including surface-velocity measurements, and surface mass balance estimated by isochronous radar stratigraphy dated with firn cores. We find that the ice rises are thickening at present (2012–2014), which started only in recent decades. Investigation of deeper radar reflectors suggests a stronger upwind-downwind contrast in surface mass balance in the past for both ice rises, with varying details. This result matches what was previously found on Blåskimen Island ice rise, which is also in the Fimbul Ice Shelf. Moreover, Kupol Moskovskij, situated at a shear margin, shows signs of recent changes in its ice-divide position, while Kupol Ciolkovskogo shows a more stable divide position. This study highlights the long-term influence of surface mass balance on ice rises, as well as the strong influence of local glaciological settings on their evolution.
Humanitarian principles and humanitarian disarmament: An operator's perspective
Authors: Dresner Josephine , Labianco Riccardo 
Published: February 2024

AbstractConceptually rooted in the efforts to ban indiscriminate weapons and both their immediate and long-term effects, humanitarian mine action and humanitarian disarmament operations have developed significantly since 1988, when the United Nations first took on work on mine action operations for the protection and benefit of local communities. A large part of those operations has been carried out by humanitarian disarmament NGOs such as the Mines Advisory Group (MAG), one of the first organizations to be established on this issue. Drawing on MAG's experience and perspective, this article explores how the humanitarian principles apply to humanitarian disarmament operations. The aim of the article is to show that as an operator on the humanitarian–development nexus, MAG considers the four humanitarian principles as a critical and necessary part of its reference framework due to the influence of the humanitarian disarmament framework, even when operating in the development space. All in all, the case of humanitarian disarmament and MAG's experience are good examples to illustrate where the humanitarian horizon is extended because of long-terms serious needs, and that humanitarian principles remain essential to keep the focus on the needs of affected populations.
An Analytical Model of Active Layer Depth Under Changing Ground Heat Flux
Authors: Zhu Modi , Wang Jingfeng , Ivanov Valeriy , Sheshukov Aleksey , Zhou Wenbo , Zhang Liujing , Mazepa Valeriy , Sokolov Alexandr , Valdayskikh Victor 
Published: February 2024

AbstractImproved modeling of permafrost active layer freeze‐thaw plays a crucial role in understanding the response of the Arctic ecosystem to the accelerating warming trend in the region over the past decades. However, modeling the dynamics of the active layer at diurnal time scale remains challenging using the traditional models of freeze‐thaw processes. In this study, a physically based analytical model is formulated to simulate the thaw depth of the active layer under changing boundary conditions of soil heat flux. Conservation of energy for the active layer leads to a nonlinear integral equation of the thaw depth using a temperature profile approximated from the analytical solution of the heat transfer equation forced by ground heat flux. Temporally variable ground heat flux is estimated using non‐gradient models when field observations are not available. Validation of the proposed model conducted against field data obtained from three Arctic forest and tundra sites demonstrates that the model is able to simulate both thaw depth and soil temperature profiles accurately. The model has the potential to estimate regional variability of the thaw depth for permafrost related applications.
Photonic neuromorphic architecture for tens-of-task lifelong learning
Authors: Cheng Yuan , Zhang Jianing , Zhou Tiankuang , Wang Yuyan , Xu Zhihao , Yuan Xiaoyun , Fang Lu 
Published: February 2024

AbstractScalable, high-capacity, and low-power computing architecture is the primary assurance for increasingly manifold and large-scale machine learning tasks. Traditional electronic artificial agents by conventional power-hungry processors have faced the issues of energy and scaling walls, hindering them from the sustainable performance improvement and iterative multi-task learning. Referring to another modality of light, photonic computing has been progressively applied in high-efficient neuromorphic systems. Here, we innovate a reconfigurable lifelong-learning optical neural network (L2ONN), for highly-integrated tens-of-task machine intelligence with elaborated algorithm-hardware co-design. Benefiting from the inherent sparsity and parallelism in massive photonic connections, L2ONN learns each single task by adaptively activating sparse photonic neuron connections in the coherent light field, while incrementally acquiring expertise on various tasks by gradually enlarging the activation. The multi-task optical features are parallelly processed by multi-spectrum representations allocated with different wavelengths. Extensive evaluations on free-space and on-chip architectures confirm that for the first time, L2ONN avoided the catastrophic forgetting issue of photonic computing, owning versatile skills on challenging tens-of-tasks (vision classification, voice recognition, medical diagnosis, etc.) with a single model. Particularly, L2ONN achieves more than an order of magnitude higher efficiency than the representative electronic artificial neural networks, and 14× larger capacity than existing optical neural networks while maintaining competitive performance on each individual task. The proposed photonic neuromorphic architecture points out a new form of lifelong learning scheme, permitting terminal/edge AI systems with light-speed efficiency and unprecedented scalability.
Ghrelin decreases sensitivity to negative feedback and increases prediction-error related caudate activity in humans, a randomized controlled trial
Authors: Pietrzak Michal , Yngve Adam , Hamilton J. Paul , Asratian Anna , Gauffin Emelie , Löfberg Andreas , Gustavson Sarah , Persson Emil , Capusan Andrea J. , Leggio Lorenzo , Perini Irene , Tinghög Gustav , Heilig Markus , Boehme Rebecca 
Published: February 2024

AbstractThe stomach-derived hormone ghrelin plays not only a role in feeding, starvation, and survival, but it has been suggested to also be involved in the stress response, in neuropsychiatric conditions, and in alcohol and drug use disorders. Mechanisms related to reward processing might mediate ghrelin’s broader effects on complex behaviors, as indicated by animal studies and mostly correlative human studies. Here, using a within-subject double-blind placebo-controlled design with intravenous ghrelin infusion in healthy volunteers (n = 30), we tested whether ghrelin alters sensitivity to reward and punishment in a reward learning task. Parameters were derived from a computational model of participants’ task behavior. The reversal learning task with monetary rewards was performed during functional brain imaging to investigate ghrelin effects on brain signals related to reward prediction errors. Compared to placebo, ghrelin decreased punishment sensitivity (t = −2.448, p = 0.021), while reward sensitivity was unaltered (t = 0.8, p = 0.43). We furthermore found increased prediction-error related activity in the dorsal striatum during ghrelin administration (region of interest analysis: t-values ≥ 4.21, p-values ≤ 0.044). Our results support a role for ghrelin in reward processing that extends beyond food-related rewards. Reduced sensitivity to negative outcomes and increased processing of prediction errors may be beneficial for food foraging when hungry but could also relate to increased risk taking and impulsivity in the broader context of addictive behaviors.
Moiré effect enables versatile design of topological defects in nematic liquid crystals
Authors: Wang Xinyu , Jiang Jinghua , Chen Juan , Asilehan Zhawure , Tang Wentao , Peng Chenhui , Zhang Rui 
Published: February 2024

AbstractRecent advances in surface-patterning techniques of liquid crystals have enabled the precise creation of topological defects, which promise a variety of emergent applications. However, the manipulation and application of these defects remain limited. Here, we harness the moiré effect to engineer topological defects in patterned nematic liquid crystal cells. Specifically, we combine simulation and experiment to examine a nematic cell confined between two substrates of periodic surface anchoring patterns; by rotating one surface against the other, we observe a rich variety of highly tunable, novel topological defects. These defects are shown to guide the three-dimensional self-assembly of colloids, which can conversely impact defects by preventing the self-annihilation of loop-defects through jamming. Finally, we demonstrate that certain nematic moiré cells can engender arbitrary shapes represented by defect regions. As such, the proposed simple twist method enables the design and tuning of mesoscopic structures in liquid crystals, facilitating applications including defect-directed self-assembly, material transport, micro-reactors, photonic devices, and anti-counterfeiting materials.
Persistence in risk and effect of COVID-19 vaccination on long-term health consequences after SARS-CoV-2 infection
Authors: Lam Ivan Chun Hang , Zhang Ran , Man Kenneth Keng Cheung , Wong Carlos King Ho , Chui Celine Sze Ling , Lai Francisco Tsz Tsun , Li Xue , Chan Esther Wai Yin , Lau Chak Sing , Wong Ian Chi Kei , Wan Eric Yuk Fai 
Published: February 2024

AbstractThe persisting risk of long-term health consequences of SARS-CoV-2 infection and the protection against such risk conferred by COVID-19 vaccination remains unclear. Here we conducted a retrospective territory-wide cohort study on 1,175,277 patients with SARS-CoV-2 infection stratified by their vaccination status and non-infected controls to evaluate the risk of clinical sequelae, cardiovascular and all-cause mortality using a territory-wide public healthcare database with population-based vaccination records in Hong Kong. A progressive reduction in risk of all-cause mortality was observed over one year between patients with SARS-CoV-2 infection and controls. Patients with complete vaccination or have received booster dose incurred a lower risk of health consequences including major cardiovascular diseases, and all-cause mortality than unvaccinated or patients with incomplete vaccination 30-90 days after infection. Completely vaccinated and patients with booster dose of vaccines did not incur significant higher risk of health consequences from 271 and 91 days of infection onwards, respectively, whilst un-vaccinated and incompletely vaccinated patients continued to incur a greater risk of clinical sequelae for up to a year following SARS-CoV-2 infection. This study provided real-world evidence supporting the effectiveness of COVID-19 vaccines in reducing the risk of long-term health consequences of SARS-CoV-2 infection and its persistence following infection.
A wireless battery-free eye modulation patch for high myopia therapy
Authors: Zhong Tianyan , Yi Hangjin , Gou Jiacheng , Li Jie , Liu Miao , Gao Xing , Chen Sizhu , Guan Hongye , Liang Shan , He Qianxiong , Lin Rui , Long Zhihe , Wang Yue , Shi Chuang , Zhan Yang , Zhang Yan , Xing Lili , Zhong Jie , Xue Xinyu 
Published: February 2024

AbstractThe proper axial length of the eye is crucial for achieving emmetropia. In this study, we present a wireless battery-free eye modulation patch designed to correct high myopia and prevent relapse. The patch consists of piezoelectric transducers, an electrochemical micro-actuator, a drug microneedle array, μ-LEDs, a flexible circuit, and biocompatible encapsulation. The system can be wirelessly powered and controlled using external ultrasound. The electrochemical micro-actuator plays a key role in precisely shortening the axial length by driving the posterior sclera inward. This ensures accurate scene imaging on the retina for myopia eye. The drug microneedle array delivers riboflavin to the posterior sclera, and μ-LEDs’ blue light induces collagen cross-linking, reinforcing sclera strength. In vivo experiments demonstrate that the patch successfully reduces the rabbit eye’s axial length by ~1217 μm and increases sclera strength by 387%. The system operates effectively within the body without the need for batteries. Here, we show that the patch offers a promising avenue for clinically treating high myopia.
Remote-carbonyl-directed sequential Heck/isomerization/C(sp2)–H arylation of alkenes for modular synthesis of stereodefined tetrasubstituted olefins
Authors: Luan Runze , Lin Ping , Li Kun , Du Yu , Su Weiping 
Published: February 2024

AbstractModular and regio-/stereoselective syntheses of all-carbon tetrasubstituted olefins from simple alkene materials remain a challenging project. Here, we demonstrate that a remote-carbonyl-directed palladium-catalyzed Heck/isomerization/C(sp2)–H arylation sequence enables unactivated 1,1-disubstituted alkenes to undergo stereoselective terminal diarylation with aryl iodides, thus offering a concise approach to construct stereodefined tetrasubstituted olefins in generally good yields under mild conditions; diverse carbonyl groups are allowed to act as directing groups, and various aryl groups can be introduced at the desired position simply by changing aryl iodides. The stereocontrol of the protocol stems from the compatibility between the E/Z isomerization and the alkenyl C(sp2)–H arylation, where the vicinal group-directed C(sp2)–H arylation of the Z-type intermediate product thermodynamically drives the reversible E to Z isomerization. Besides, the carbonyl group not only promotes the Pd-catalyzed sequential transformations of unactivated alkenes by weak coordination, but also avoids byproducts caused by other possible β-H elimination.
Quiescence enables unrestricted cell fate in naive embryonic stem cells
Authors: Khoa Le Tran Phuc , Yang Wentao , Shan Mengrou , Zhang Li , Mao Fengbiao , Zhou Bo , Li Qiang , Malcore Rebecca , Harris Clair , Zhao Lili , Rao Rajesh C. , Iwase Shigeki , Kalantry Sundeep , Bielas Stephanie L. , Lyssiotis Costas A. , Dou Yali 
Published: February 2024

AbstractQuiescence in stem cells is traditionally considered as a state of inactive dormancy or with poised potential. Naive mouse embryonic stem cells (ESCs) can enter quiescence spontaneously or upon inhibition of MYC or fatty acid oxidation, mimicking embryonic diapause in vivo. The molecular underpinning and developmental potential of quiescent ESCs (qESCs) are relatively unexplored. Here we show that qESCs possess an expanded or unrestricted cell fate, capable of generating both embryonic and extraembryonic cell types (e.g., trophoblast stem cells). These cells have a divergent metabolic landscape comparing to the cycling ESCs, with a notable decrease of the one-carbon metabolite S-adenosylmethionine. The metabolic changes are accompanied by a global reduction of H3K27me3, an increase of chromatin accessibility, as well as the de-repression of endogenous retrovirus MERVL and trophoblast master regulators. Depletion of methionine adenosyltransferase Mat2a or deletion of Eed in the polycomb repressive complex 2 results in removal of the developmental constraints towards the extraembryonic lineages. Our findings suggest that quiescent ESCs are not dormant but rather undergo an active transition towards an unrestricted cell fate.