bluuebunny/crossref_metadata_2025_split huggingface dataset:
Assessment of Knowledge, Attitude, and Practice of Pharmacovigilance and Materiovigilance among Oral Health Practitioners in India
Authors: Yadav Lucky , Mehra Pravesh , Vasisth Diwakar , Mattu Navraj , Biswas Krishna , Yadav Neelam 
Published: February 2024

ABSTRACT

Aim:
This electronic survey was carried out to assess the knowledge, attitude, and practices among the oral health practitioners.

Methods:
A questionnaire survey was conducted among undergraduates, graduated practitioners, and specialist practitioners. A Google Form that included a specified instruction format, informed consent with a clear description of the purpose of the study, and questions in different categories were sent through Whatsapp and email. Descriptive statistics were used to analyze responses. The association of knowledge and attitude with respect to oral health professionals was analyzed with the Chi-square test.

Results:
The questionnaire was completed by 570 participants. Thirty percent of participants encountered ADR related to the drugs available in the market and 33.2% of participants encountered adverse reaction related to materials used in practice. ADR should be reported as soon as it is detected, according to this study about 12.1% of participants reported the ADRs, and this reporting is primarily for patient safety. Almost 66.8% of participants perceived that dental products can cause ADR owing to a lack of information about ADR and reporting procedures, or due to fear of legal concerns. Only about 9.5% of the participants had previously attended an ADR workshop.

Conclusion:
Oral health practitioners have a general understanding of ADR; however, there is substantial evidence of underreporting and a lack of reporting system information. Organizing an orientation program and raising awareness about ADR reporting could help improve spontaneous reporting and better patient care.
A Randomized Controlled Trial Comparing the Management of Incomplete Abortion with Oral 600 mg Misoprostol with Manual Vacuum Aspiration (MVA)
Authors: Madhual Niramaya , Tiwari Heena Dixit , Das Susmita , Kamboj Saloni , Thakkar Smit , Kashif Hala , Mahajan Akriti 
Published: February 2024

ABSTRACT

Introduction:
In the first trimester, almost one in five identified pregnancies end in spontaneous miscarriage, and another 22% result in induced abortion. After a spontaneous and/or induced abortion, there may be retained products of conception (POC). Because of its relatively poor efficacy and the unpredictability of the time interval until spontaneous evacuation, expectant treatment is not often chosen by healthcare professionals. In view of these facts, the current study’s objective was to weigh the effectiveness of MVA and oral misoprostol 600 mg in managing incomplete abortion.

Materials and Procedures:
The investigation was conducted at the tertiary care center in India. The survey was conducted for one year. Subjects were selected from those attending the department for either spontaneous or induced abortions. A total of 230 women were randomly assigned to receive the interventions of a single dose of oral misoprostol 600 mcg or MVA. They were equally distributed to two groups and observed for the various parameters of success, signs and symptoms, satisfaction, and complications. The obtained values were compared statistically for the significance at <0.05 of P values.

Results:
Of the 200 subjects (30 lost to follow-up), there was no significant variance in the demographics, clinical outcomes, and complications between the groups. However, the pain, fever, shivering, and satisfaction parameters were statistically variant between the groups. Fever, shivering, and pain were lower for the MISO subjects while satisfaction was reported higher from subjects in MISO group.

Conclusion:
MISO and MVA are acceptable, safe, and efficient therapies for first-trimester un-complicated incomplete abortion. Nonetheless, misoprostol appears to be a marginally superior option to MVA in terms of accessibility, low therapy costs, reduced pain, and reduced demand for specialized personnel or equipment.
Analysis Comparing the Recovery of Airway Reflexes and Cognitive Ability After Sevoflurane with Desflurane Anesthesia
Authors: Khan Mohammed Wajid Ali , Das Prajnyananda , Bhavani V , Thakkar Smit , Nagella Sai Prannoy , Dubey Alok 
Published: February 2024

ABSTRACT

Introduction:
Although sevoflurane and desflurane have nearly identical blood-gas solubilities, current research suggests that airway reflexes recover more quickly with desflurane than sevoflurane; however, cognitive function recovery varies substantially. The current study was piloted to appraise the lengths of time needed to recover from anesthesia following desflurane and sevoflurane anesthesia.

Materials and Methods:
A prospective clinical trial was piloted among 70 adult non-obese subjects who underwent elective surgery and were classified I–II by the “American Association of Anesthesiologists (ASA)”. Sevoflurane and desflurane were tested among the subjects who were equally distributed. These agents were used in accordance with a normal general anaesthesia procedure. After they were extubated, tests for regaining cognitive function and airway reflexes were carried out, and different time intervals were recorded. The observations were calculated and P < 0.05 was used to conduct the statistical analysis.

Results:
The average amount of time that passed between the patient’s first vocal response and their first successful completion of the swallowing test was analogous between the two groups (T2) with 5.25 ± 3.11 vs 5.01 ± 2.12 in sevoflurane and desflurane, respectively. There was no significant variance at T2. For all the other time intervals of T1, T3, and T4, there was evidence of the significant variance.(P = 0.003; 0.0013; <0.001, respectively).

Conclusion:
Desflurane causes patients to recover more quickly than sevoflurane does after laparoscopic cholecystectomy under controlled circumstances.
Effect of Staining Beverages on Color Stability of Composite: A Spectrophotometric Study
Authors: Thakkar Radhika , Maini Anuj P. , Mogla Sahil , Hussain Qadri Syed Shah , Varma Praveen K. , Dubey Alok 
Published: February 2024

ABSTRACT

Objective:
This study used spectrophotometry to examine how staining beverages affect the color stability of three commercial composite materials (nanohybrid composite (A), bulk fill composite (B), and flowable composite (C)) over time.

Materials and Methods:
Composite discs were randomly divided into groups. The specimens were kept in coffee, tea, red wine, and cola for 14 days at 37°C in the dark. At baseline, 7 days, and 14 days, spectrophotometers measured color. Calculated and analyzed color differences (E).

Results:
Staining beverages changed the color of all composites. Composite material A had the best color stability, whereas material C stained beverages the most. Red wine and coffee discolored composites most. Discoloration increased over the 14-day immersion period.

Conclusion:
Composite materials with better color stability were material A. Red wine and coffee discolored composites most. When choosing restorative materials, dentists should consider composite materials’ color stability for long-lasting, visually acceptable results.
Evaluation of Extraction of Teeth without Alteration in Aspirin Therapy: A Cross Sectional Study
Authors: Almuntashri Ahmed Ali , Kaur Manpreet , Verghese Yohan , Azad Abdul Kalam , Dalai Radha Prasanna , Bhasin Ritasha , Sonkar Tanu Priya 
Published: February 2024

ABSTRACT

Aim:
The study was done to evaluate extraction of teeth without altering the aspirin therapy.

Materials and Method:
Hundred patients taking aspirin therapy requiring extraction of teeth were separated into two groups with 50 samples in each. Group I continued the aspirin therapy during extraction of teeth on one occasion, and the same patients who discontinued the aspirin therapy 72 hours before extraction of teeth on another occasion become Group II.

Result:
The mean blood loss showed slightly increased bleeding in Group I in comparison to Group II. The average bleeding time and mean INR was statistically significant among both groups. The mean clotting time and mean platelet count were not statistically significant among groups.

Conclusion:
There was no alteration in bleeding after extraction in patients with low doses of aspirin therapy.
Evaluation of the Periodontal Inflammatory Effect on Erythrocyte Sedimentation Rate: A Clinical Study
Authors: Yadav Bipin K. , Thakur Rajesh K. , Kannaujia Sanjay K. , Mishra Rahul , Maurya Geeta , Dixit Ashutosh 
Published: February 2024

ABSTRACT

Context:
The link between oral infections and systemic disease is a well-proven hypothesis in the current literature. This relationship is the result of interaction between periodontal microbe that triggers inflammatory processes leading to the secretion of cytokines and other mediators of inflammation resulting in the systemic effects of pathogenesis.

Materials and Methods:
In this study, erythrocyte sedimentation rate (ESR), probing pocket depth, plaque index, gingival index, and the parameters were assessed initially and 1 month after scaling and root planing (SRP).

Statistical Analysis Used:
The paired t-test and the Pearson correlation were needed to examine and compare measured data.

Results:
The data from the study reveal that all the clinical parameters like the plaque index, the gingival index, and the probing pocket depth were statistically significantly reduced after 1 month of SRP with respect to baseline. While ESR mean value was also reduced, that is, 3.27 ± 1.24 mm/hr which was also considered statistically significant.

Conclusions:
The findings from the study showed a positive correlation between periodontal inflammation and ESR.
Evaluation of Patient Acceptance and Compliance with Clear Aligners vs. Lingual Braces: A Randomized Trial
Authors: Alfawzan Ahmed A. 
Published: February 2024

ABSTRACT

Background:
The efficacy of orthodontic treatments is often influenced by patient acceptance and compliance. This study aims to compare patient acceptance and compliance between clear aligners and lingual braces in a randomized clinical trial.

Materials and Methods:
A total of 100 patients requiring orthodontic treatment were randomly allocated into two groups: clear aligners (n = 50) and lingual braces (n = 50). Data on patient acceptance and compliance were collected through self-reported questionnaires and clinical observations over a period of 12 months.

Results:
Patient acceptance was significantly higher in the clear aligner group, with 80% reporting high levels of comfort, compared to 60% in the lingual braces group (P < 0.05). Compliance rates were 92% for clear aligners and 85% for lingual braces (P = 0.1).

Conclusion:
Clear aligners showed a higher level of patient acceptance and a slightly better compliance rate, although the difference was not statistically significant. These findings suggest that clear aligners may be a preferable option for patients prioritizing comfort.
To Evaluate the Effect of Vitamin B Complex on Wound Healing – A Clinical and Microbiological Study
Authors: Kalsi Rupali , Bhushan Kala S. , Mathur Mohit K. , Gupta Vineeta , Gupta Deepesh K. , Pandey Sandeep K. 
Published: February 2024

ABSTRACT

Background:
The purpose of this study is to explore the effect of vitamin B complex supplementation following periodontal flap surgery on clinical and microbiological parameters.

Materials and Methods:
A randomized controlled trial on 10 patients with periodontitis in split-mouth design was undertaken to find the effect of vitamin B complex supplementation with open flap debridement on periodontal wound healing. Multiplex polymerase chain reaction (PCR) for Tannerella forsythus and Porphyromonas gingivalis was done using subgingival plaque samples at 0 and 90th day.

Results:
The results showed a significant reduction (P < 0.01) of clinical (plaque index, gingival index, gingival bleeding index, probing pocket depth, and relative attachment level) and microbial profile in both treatment groups, whereas on intergroup analysis, more reduction in all clinical parameters were observed in the test group, but statistically, the results were insignificant.
Al-Based Detection of Dental Caries: Comparative Analysis with Clinical Examination
Authors: Alam Mohammad K. , Alanazi Nawadir H. , Alazmi Mona S. , Nagarajappa Anil K. 
Published: February 2024

ABSTRACT

Dental caries pose a significant public health concern, affecting a vast population globally. Traditional clinical examination methods, although reliable, can be subject to human error and time-consuming. Artificial intelligence (AI) technologies have emerged as promising tools to enhance diagnostic accuracy and efficiency. This study explores the potential of AI in revolutionizing dental caries detection.

Materials and Methods:
A cohort of 50 patients with varying degrees of dental caries participated in this comparative analysis. Clinical examination by dental professionals served as the gold standard for caries detection. AI algorithms were trained using dental images, and their performance was evaluated against the clinical examination results.

Results:
The AI-based detection system demonstrated a sensitivity of 92% and a specificity of 85% in identifying dental caries, with an overall accuracy of 88%. The clinical examination yielded a sensitivity of 86% and a specificity of 90%, resulting in an overall accuracy of 88%. Statistical analysis indicated no significant difference between AI-based detection and clinical examination (P > 0.05).

Conclusion:
AI technology exhibits promise as an adjunctive tool for dental practitioners, potentially reducing diagnostic errors and improving efficiency. Integrating AI into routine dental practice may aid in early caries detection and promote better oral health outcomes.
Comparative Evaluation of Quality Management Practices in the Public and Private Hospitals in Visakhapatnam District: An Original Research
Authors: Tiwari Rahul V. C. , Sharma Sandesh K. , Sahoo Sujit R. , Velthuru Srujan K. , Basavarajaiah Jeevan Matada , Kazi Madiha , Dixit Heena 
Published: February 2024

ABSTRACT

Background:
In the Visakhapatnam District, this study compares the quality management procedures used by public and private hospitals. Knowing how these practices are similar and different from one another can help inform policy decisions and improve the quality of health care.

Materials and Methods:
A cross-sectional study design was used, and 100 hospitals from both public (50 hospitals) and private (50 hospitals) were included in the sample size. A standardized questionnaire that evaluated different aspects of quality management practices was used to gather the data. Descriptive statistics and inferential tests were used in the quantitative analysis.

Results:
Significant variations in quality management procedures between public and private hospitals were found. In terms of patient happiness, service responsiveness, and technological use, private hospitals scored better. Regarding accessibility, cost, and equity of healthcare services, public hospitals fared better.

Conclusion:
The report emphasizes the necessity of focused initiatives to improve quality management procedures in both public and commercial institutions. Collaboration between the two sectors can make it easier to deploy evidence-based tactics and share best practices to raise overall healthcare quality in the Visakhapatnam area.
Evaluation of Prosthodontic Complications in Screw-Retained and Cement-Retained Crowns in Dental Implants: An Original Research
Authors: Rajput Mansi , Kohli Arshdeep S. , Abdul Hina N. , Sandhu Sunpreet K. , Thakkar Radhika , Karre Shivani 
Published: February 2024

ABSTRACT

Aim:
Single-tooth implant restorations, whether screw-retained or cement-retained, are essential for prosthodontic rehabilitation despite having low design flexibility, cosmetic appeal, and high 5-year survival rates.

Materials and Methods:
A study involving 14 patients with missing mandibular first molars used 28 implants and cement-retained and screw-retained prostheses. Patients had a single edentulous gap, adequate dental hygiene, and sufficient bone volume at the implant site. The study adhered to the Helsinki Declaration, followed WHO 2007 safety guidelines, and evaluated soft tissue, bone height, and bone loss. Data analysis included the Student’s t-test and Mann–Whitney U-test.

Results:
In patients between the ages of 17 and 46, single-implant restorations were compared with cement- and screw-retained at 6 months. Abutment screw loosening and peri-implant soft-tissue traits did not differ significantly from one another.

Conclusion:
The study compared screw- and cement-retained implant restorations in 28 single-tooth implant-supported prostheses over a 6-month functional loading period, finding no significant improvement in either approach.
Effect of Sterilization and Irrigating Solutions on Nanostructure Alteration of Ni-Ti Rotary Instruments in Endodontics: An Atomic Force Microscopic Study
Authors: Shaik Izaz , Dasari Bhargavi , Alapati Satish , Dhavala Padma C. , Tiwari Rahul , Tiwari Heena Dixit 
Published: February 2024

ABSTRACT

Aim:
This study aimed to evaluate the effect of 5.25% sodium hypochlorite (NaOCl) and 17% ethylenediaminetetraacetic acid (EDTA) and sterilization on the nanostructural alteration of nickel titanium (Ni-Ti) rotary file systems in endodontics using the atomic force microscopy (AFM).

Materials and Methods:
The study was performed on four commercially available rotary Ni-Ti files: group I—Vortex Blue (Dentsply), group II—ProTaper Next (Dentsply), group III—Mtwo (VDW), and group IV—iRaCe (FKG). Each group was divided into four subgroups (n = 4), that is, subgroup A—control (new rotary file), subgroup B—subjected for five cycles of autoclave, subgroup C—immersed in 5.25% NaOCl for 5 minutes, and subgroup D—immersed in 17% EDTA solutions for 5 minutes. All the specimens were evaluated with AFM using roughness average (RA) and root-mean-square (RMS) values for surface roughness.

Results:
Among control groups, Vortex Blue showed the least RA and RMS values; the highest surface roughness was seen with Mtwo files. All the Ni-Ti rotary files showed a statistically significant (P <0.05) increase in surface hardness when subjected to autoclave and treatment with different irrigating solutions. In particular, 17% EDTA caused the highest surface deterioration in all the groups.

Conclusion:
AFM analysis revealed increased surface roughness values recorded for all the rotary files when treated with irrigating solutions and autoclave cycles.
Morphological Variation of Mandibular Molars in Rohilkhand Population: An Original Research
Authors: Singh Tanu , Bathla Saurav , Dutta Saurav Kumar , Mohammed Minhaj Ahmed Amer , Jethi Navdeep , Chansoria Harsh , Pulluri Saraswathi Sravani 
Published: February 2024

ABSTRACT

Introduction:
In-depth knowledge of common and aberrant pulp morphology is essential for appropriate diagnosis and treatment planning before commencing root canal treatment. The radicular morphology of mandibular molars has been extensively studied. Considerable variation in the number of canals and roots found in these teeth has been reported.

Aim:
The purpose of this study is to investigate the root canal morphology of the mandibular molars among the Rohilkhand population using Dentascan.

Materials and Methods:
Dentascan images of mandibular molar were taken from 99 extracted teeth that were collected from the Department of Oral Surgery and Maxillofacial Surgery, Institute of Dental Sciences, Bareilly, and private clinics. The examination of root canal systems of the teeth was based on Vertucci’s classification.

Results:
The mandibular molar (n = 99) were taken. Out of the 99 teeth examined, three canals were seen in 60 (60.6%) teeth, four canals in 39 (39.4%) teeth, 3% had extra distal roots, and 6% with C-shaped canals.

Conclusion:
Among mandibular first molars, only 3% had three roots. Mesial roots of the first molar typically present with two canals and two apical foramina with type IV or II canal configuration. Most distal roots of the first molar presented with a type I canal configuration. The remainder were distributed mainly between types II, IV, III, and V. Among 99 mandibular molars, 6% had single C-shaped roots.
The Effect of a Low-Carbohydrate Diet on Periodontal Health and Inflammation in Patients with Type 2 Diabetes
Authors: Bagde Hiroj S. , Alam Mohammad K. , Alhamwan Abdullah Khalid A , Aljubab Hamed Muhanned H , Alrashedi Faisal Fraih A , Aljameeli Dhari Hameed M , Sghaireen Mohammed G. 
Published: February 2024

ABSTRACT

Background:
The interaction between type 2 diabetes and periodontal disease underscores the importance of exploring dietary interventions that could mitigate inflammation and improve periodontal health in diabetic patients.

Materials and Methods:
This randomized controlled trial included 100 patients with type 2 diabetes who were equally divided into two groups: Group A (low-carbohydrate diet) and Group B (control group). Patients in Group A followed a low-carbohydrate diet for 12 weeks, while Group B maintained their regular dietary habits. Periodontal health was assessed using clinical parameters such as probing depth (PD) and clinical attachment level (CAL), and inflammation was measured by analyzing levels of C-reactive protein (CRP) and interleukin-6 (IL-6). Statistical analyses were performed using appropriate tests.

Results:
After 12 weeks, Group A exhibited significant improvements in periodontal health compared to Group B. The mean PD reduction was 0.5 mm in Group A and 0.1 mm in Group B, with a corresponding mean CAL gain of 0.3 mm in Group A and no significant change in Group B. Inflammatory markers also showed favorable outcomes in Group A, with a decrease of 1.2 mg/L in CRP levels and 20% reduction in IL-6 levels. In contrast, Group B demonstrated minimal changes in inflammatory markers. The differences in PD, CAL, CRP, and IL-6 levels between the two groups were statistically significant (P < 0.05).

Conclusion:
The adoption of a low-carbohydrate diet for 12 weeks demonstrated significant improvements in periodontal health and reduction of inflammation in patients with type 2 diabetes.
Prevalence and Association of Calcified Pulp Stones with Periodontitis: A Cone-Beam Computed Tomography Study in Saudi Arabian Population
Authors: Alqahtani Abdullah Saad 
Published: February 2024

ABSTRACTThis study aimed to identify the prevalence and association of periodontitis and pulp stone (PS) along with the clinical variables. This study assessed the cone-beam computed tomography (CBCT) records to identify the presence of PS and clinical periodontitis records were used to determine the stages of periodontitis. The Chi-square test was used to evaluate the relationship between study parameters. Logistic regression was used to determine the association between PS and periodontitis. A total of 228 CBCT records were conveniently selected for this study based on the inclusion and exclusion criteria. Cohen’s kappa analysis showed near to perfect scores for both examiners. The Chi-square test showed that CBCT records from the age range 41–50 years, male patients, and stage II of periodontitis prevalently showed pulp stones; however, there were no significant differences observed between the PS and clinical variables. However, gender, involvement of tooth, and stages of periodontitis showed significant distribution of the PS. Logistic regression showed that the stages of periodontitis showed no significant association with PS in patients with periodontitis. Moreover, multivariate odds ratio adjustment did not alter the outcome. Periodontitis is not associated with the presence of PS in the current population.