bluuebunny/crossref_metadata_2025_split huggingface dataset:
Training Simulation Courses in the System of Postgraduate Education of Doctors
Authors: Богданьянц М.В. , Минакова Г.М. 
Published: April 2024

Даются оценка и анализ программ постдипломной подготовки кадров высшей квалификации «Актуальные вопросы неотложной помощи в педиатрии с обучающим симуляционным курсом», реализуемых на кафедре пропедевтики детских болезней, поликлинической и неотложной педиатрии Астраханского государственного медицинского университета. Демонстрируется востребованность подобных программ практическим здравоохранением, их практикоориентированность. Обсуждается значение симуляционного обучения для повышения качества образования, отработки и закрепления практических навыков, необходимых для оказания неотложной помощи детям разных возрастов, готовности врачей-педиатров решать профессиональные задачи диагностики различных жизнеугрожающих состояний, лечения на догоспитальном этапе.
An assessment and analysis of postgraduate training programs for highly qualified personnel “Actual issues of emergency care in pediatrics with a training simulation course” implemented at the Department of Propaedeutics of Childhood Diseases, Polyclinic and Emergency Pediatrics of the Astrakhan State Medical University are given. Demonstrates the demand for such programs in practical healthcare, their practice orientation. The importance of simulation training for improving the quality of education, developing and consolidating the practical skills necessary for providing emergency care to children of different ages, the readiness of pediatricians to solve professional problems of diagnosing various life-threatening conditions, prehospital treatment is discussed.
Implementasi Kebijakan Moderasi Beragama terhadap Harmoni Pendidikan Islam di SMAN 1 Bae Kudus
Authors: Rozaq Mohammad Khoirur , Anhar Sofyan Habibi , Miftah Muhammad 
Published: April 2024

Fokus penelitian ini adalah untuk mengetahui penerapan moderasi beragama terhadap harmoni pendidikan Islam di SMAN 1 Bae Kudus. Subjek studi ini melibatkan guru Pendidikan Agama Islam dan Kristen di SMAN 1 Bae Kudus. Metode penelitian yang digunakan adalah deskriptif kualitatif. Teknik pengumpulan data pada penelitian ini dilakukan melalui dokumentasi, wawancara, dan observasi. Hasil dari penelitian ini membahas sekolah multikultural di SMAN 1 Bae Kudus yang terdapat beberapa keberagaman, diantaranya; keberagaman agama, ras, suku, sosial budaya dan latar belakang pendidik dan peserta didik. Akan tetapi faktor- faktor keragaman tersebut tidak menjadikan sebuah konflik yang dapat memecah belah di lingkungan sekolah, justru dengan perbedaan mereka saling menghargai dan toleransi antar sesama. Bahkan, penerapan moderasi beragama di SMAN 1 Bae Kudus dimuat dalam visi dan misi sekolah. Penerapan moderasi beragama di SMAN 1 Bae Kudus beberapa diantaranya pemahaman moderasi yang disampaikan peserta didik di dalam dan luar kelas, penguatan moderasi dalam kegiatan- kegiatan keagamaan yang dipraktekkan dalam kegiatan jum’at berkah, takziyah bersama, dan pembuatan konten yang bersifat toleransi. Hasil penerapannya, tidak hanya memperkuat pemahaman peserta didik, tetapi juga memberikan nilai postif dan toleransi terhadap perbedaan. Hal ini membawa dampak positif pada lingkungan pendidikan yang inklusif, serta menciptakan harmoni keberagaman yang memungkinkan untuk meminimalkan konflik atau kasus keberagaman. Diharapkan penelitian ini dapat meningkatkan pemahaman yang mendalam mengenai moderasi beragama bagi pembaca dan hubungan kerukunan dalam keberagaman antar peserta didik dari berbagai latar belakang sehingga dapat menciptakan harmoni keberagaman yang memungkinkan untuk meminimalkan konflik pada lingkungan sekolah.
Assessment of knowledge of accredited social health activists regarding antenatal & neonatal care in a block of Haryana
Authors: Sharma Seema , Kumar Amit , Poonia Ankesh , Pandey Suryamani 
Published: April 2024

Improving maternal & child health has been an essential tool for achieving health for all. The discourse on the Accredited Social Health Activist’s (ASHA’s) role centers around three typologies -as an activist, as a link worker or facilitator, and as a community level health care provider.To assess knowledge of ASHA workers regarding antenatal and neonatal care in a block of Haryana. The present cross-sectional, community-based study was conducted in block Barwala, district Hisar of Haryana. Universal sampling technique was used. A predesigned, pretested, semi-structured schedule was used to collect the information, which included details of socio-demographic profile of ASHA workers and questions about knowledge of antenatal & postnatal care. Appropriate statistical tests like frequencies and percentages test were applied to analyze the collected data.Only 6.9% ASHA workers told about benefits of early registration of pregnancy. Majority of ASHA workers had inadequate knowledge about identification of danger signs during pregnancy and infancy, duration of trimester. Majority of ASHA workers had adequate knowledge about breast-feeding practices however about half of ASHA workers had inadequate knowledge about duration of colostrum. Only about one third ASHA workers had adequate knowledge regarding weighing machine & colour zone used for identify malnutrition.: It is important to reorient ASHA workers at field level and supportive supervision also plays an important role.
Pattern and distribution of injuries associated with road traffic accident in Haldwani (Nainital) - An autopsy based study
Authors: Hatwal Pooja , Devassy Shinto , Bhaisora Chandra Prakash 
Published: April 2024

Indiais one of the fastest growing economies. There is a rapid inflation of vehicles on the road that range from motorcycles to heavy vehicles which also shows an active surge in the fatal road accidents. This study is focussed to find out the pattern and distribution of injuries in fatal road traffic accident cases in Kumaon region of Uttarakhand as to plan at the time of policy making and traffic law implementation.: The present study was conducted in the department of Forensic Medicine & Toxicology of Government Medical College, Haldwani from January 1 2019 to December 31 2019, on total 110 cases of RTA brought to mortuary for medico-legal post mortem examination.: Maximum number of cases sustained head and neck injuries (42 out of 110 externally) followed by extremities injury (28 out of 110). Total 38 cases out of 110 sustained head and neck injuries internally, followed by abdominal injuries (28 cases). Abrasions (30 cases) and laceration (29 cases) were commonest type of external injury noted in RTA cases followed by contusion (22 cases) and fracture (19 cases). Most common cause of death among RTA victims was head injury (40 out of 110 cases) followed by shock and haemorrhage (37 out of 110 cases).
Comparison of two methods in maxillary canine retraction
Authors: Duran Melike , Altinisik Resul , Altug Bicakci Ali 
Published: April 2024

The aim of this prospective clinical study is to evaluate the effects of laceback and Uprighter techniques on maxillary canine retraction using digital models and panoramic radiographs and to compare the results.Sixteen patients (10 females, 6 males) with an average chronological age of 16.24±2.99 years, requiring fixed orthodontic treatment with upper canines located in a high vestibular position and the need for bilateral first premolar extraction, were included in this study. 0.018-inch Roth brackets were used in the patients. In this split-mouth design study, while laceback was used on one side, Uprighter was used on the other side. Tooth movements were measured on three-dimensional models and panoramic radiographs obtained at the beginning of treatment (T0), 2 months later (T1), and 3.5 months later (T2). Two-way analysis of variance was applied for the comparison of differences between the groups in repeated measurements.The difference between groups was found to be statistically significant in terms of canine distalization, canine rotation, and molar angulation amounts. There was no statistically significant difference in the other parameters.Both uprighter and laceback techniques can be applied in maxillary canine cases located in the high vestibule. When Uprighter is used, the canine is distalized much more. However, it should be noted that while more molar tipping may occur when laceback is used, more canine distopalatal rotation may occur when uprighter is used.
Non-Destructive Prediction of Chemical Content in Palm Oil Fruit Using Near-Infrared Spectroscopy and Artificial Neural Network
Authors: Adiarifia Nissa , Budiastra I Wayan , Mardjan Sutrisno Suro 
Published: April 2024

Oil and water content are an important quality criteria of crude palm oil (CPO) resulted from palm oil fruit processing. Those contents are usually determined using chemical method in the laboratory. This method is time consuming, long procedure, and destructive. Some efforts had been carried out to determine oil and water content of palm oil fruit non-destructively using some methods including Near-Infrared Spectroscopy (NIRS), but the results had not been satisfied. This research aims to assess Artificial Neural Network (ANN) and NIRS method to predict oil and water content of palm oil fruit’s non-destructively. The samples were palm oil fruits with ten maturity levels harvested from plantation in Bogor. Sample’s reflectance was measured with spectrometer NIR-Flex 500 at wavelength of 1000-2500 nm. After that, oil and water content were determined using chemical method. Some pre-treatments of NIR spectra namely normalization, savitzky-golay first derivative, their combinations, and standard normal variate were applied. Multivariate analysis such as PLS were carried out and the results of Factor Component (FC) were input for ANN model. The result showed the best method to predict oil content was combination savitzky-golay first derivative and normalization pre-treatment using PLS-ANN with 20 FC (R2=0.99; SEC=0,58%, RPD = 29.89; CV = 2.47%). For water content, the best prediction was standard normal variate pre-treatment using PLS-ANN with 20 FC (R2=0.99; SEC=1,07%, RPD=20.68; CV=1,73%). The result shows that developed ANN and NIRS can predict oil and water content of palm oil fruit non-destructively.
ANALYSIS OF PHYSICAL ACTIVITY TO IMPROVE STUDENTS BASIC MOVEMENT SKILLS PHYSICAL LITERACY BASED PRIMARY SCHOOL
Authors: Ardiana Pradipta Ahdha 
Published: April 2024

Abstract This literature review study is based on this The current education pattern cannot accommodate the needs of each individual to grow optimally. Most current education patterns do not provide enough space for students' uniqueness in carrying out physical activities. Mastery of basic movements needs to be given to children in the form of physical activity. Physical activity that is designed needs to increase and stimulate children to move without compulsion. The physical activity provided can be in the form of Physical Literacy . The literature review method was carried out on three articles obtained from a number of databases, PubMed, EBSCO, and Springer Link. Keywords for searching articles are physical activity, physical literacy , basic movement skills, physical literacy . Researchers use "AND" as a Boolean operator. The results of the literature review are that the development of a physical activity model to improve elementary school students' basic movement skills is based on physical literacy. The results of the review article are: 1) Physical activity improves health, 2) Good physical literacy knowledge in children aged 7-12 years, 3) Developing physical literacy. The conclusion from the literature review is that understanding physical activity based on the concept of physical literacy can improve health. A high understanding of physical literacy is related to the holistic development of children aged 7-12 years, namely if a person's body is healthy then they will grow and develop optimally. Traditional games can develop elementary school students' physical literacy. These results are based on the improvement achieved by students in the aspects of understanding how to perform movements, movement skills and enjoyment.

Keywords: Physical activity, basic movement abilities and Physical Literacy
Combined SNPs sequencing and allele specific proteomics capture reveal functional causality underpinning the 2p25 prostate cancer susceptibility locus
Authors: Wei Gong-Hong , Dong Dandan , Zhang Peng , Liu Mengqi , Wei Yu , Wang Zixian , Xu Wenjie , Zhang Qixiang , Zhu Yao , Zhang Qin , Yang Xiayun , Zhu Jing , Wang Liang 
Published: April 2024

Abstract
Genome wide association studies (GWASs) have identified numerous risk loci associated with prostate cancer, yet unraveling their functional significance remains elusive. Leveraging our high-throughput SNPs-seq method, we pinpointed rs4519489 within the multi-ancestry GWAS-discovered 2p25 locus as a potential functional SNP due to its significant allelic differences in protein binding. Here, we conduct a comprehensive analysis of rs4519489 and its associated gene, NOL10, employing diverse cohort data and experimental models. Clinical findings reveal a synergistic effect between rs4519489 genotype and NOL10 expression on prostate cancer prognosis and severity. Through unbiased proteomics screening, we reveal that the risk allele A of rs4519489 exhibits enhanced binding to USF1, a novel oncogenic transcription factor (TF) implicated in prostate cancer progression and prognosis, resulting in elevated NOL10 expression. Furthermore, we elucidate that NOL10 regulates cell cycle pathways, fostering prostate cancer progression. The concurrent expression of NOL10 and USF1 correlates with aggressive prostate cancer characteristics and poorer prognosis. Collectively, our study offers a robust strategy for functional SNP screening and TF identification through high-throughput SNPs-seq and unbiased proteomics, highlighting the rs4519489-USF1- NOL10 regulatory axis as a promising biomarker or therapeutic target for clinical diagnosis and treatment of prostate cancer.
RSM assisted phytochemical profiling of Vitex negundo and molecular docking studies of biological active compounds with target proteins
Authors: Sharma Eti , Gaur Nisha , Singh Sandeep , Mathur Kartavya , Kumar Krishna , Wahi Nitin , Garg Gunjan 
Published: April 2024

Abstract

Vitex negundo(Family-Verbenaceae) is a remarkable medicinal plant with numerous therapeutic applications. In this study, phytochemical screening was performed in Vitex negundoleaf extract, and extraction optimization was performed by applying response surface methodology (RSM). Methanolic extract and microwave-assisted extraction (MAE) were found to be appropriate for obtaining the maximum yield of bioactive compounds. In single-factor analysis, solvent concentration, microwave power, and time of extraction variations were analyzed to calculate the amount of TPC, TFC, and TAC in the extract. The quantity of TPC, TFC, and TAC were fairly obtained from 60%–95% (v/v) methanol concentration, 540 -900 W microwave power, and 60–90 s extraction time. Furthermore, we also employed the response surface methodology (RSM) for optimizing microwave-assisted extraction of Vitex negundo leaves by considering three key parameters: solvent concentration, extraction temperature, and extraction duration. Condition optimization for the extraction were obtained at 95% (v/v) methanol, 720W, and 90s with TPC (227.6 mg gallic acid equivalent (GAE)/g sample), TFC (978.2 mg RE/g sample), and TAC (82.13 mg ascorbic acid equivalents/g sample). The characterization of methanol extract of Vitex negundowas done by FTIR and GC–MS to identify the various active groups and types of bioactive constituent’s presence in the extract. Subsequently, the compounds were evaluated for their bioactivity through molecular docking interactions with target proteins in silico. Furthermore, the antibacterial activity of the optimized extract was studied against two Gram +ve (Bacillus sphaericus, Pectobacterium) and two Gram-ve (Escherichia coli, Pseudomonas aeruginosa) bacteria, and the inhibitory effect was observed in all four tested bacteria. The highest antibacterial activity was shown against B. sphaericus (19± 0.087) and E. coli (19±0.064) followed by Pectobacterium (18±0.068) and Pseudomonas(13±0.093). The hemolytic activity of the optimized leaf extract (at a dose of 20µg/ml) shows a minimum hemolytic activity, i.e., 1.33± 0.06 %. It may be concluded from the study that Vitex negundo is potential and safe source of natural antioxidants that can be utilized in green therapeutics.
Discrete Wavelet Transform and Spectral Subtraction Based Speech Enhancement Algorithm for Hearing Aid Application
Authors: Iqbal Yasir , Zhang Tao , Geng Yanzhang , Fahad Muhammad , Zhao Xin , Rahman Sadiq Ur , Iqbal Anjum 
Published: April 2024

Abstract
Hearing aids are small electronic devices intended to help those with hearing loss improve their hearing ability with the use of advanced audio signal processing techniques and technologies. Usually, in hearing aids, a set of speech enhancement methods are utilized to improve speech signal quality in low signal-to-noise ratio (SNR) environments. In speech processing, Discrete Wavelet Transform (DWT) algorithm and Spectral Subtraction (SS) filter are some of the most commonly used methods today when handling background noise in hearing aids. However, these speech enhancement systems have drawbacks like in DWT, the selective thresholding face problems when applying to distinct types of noise with different frequencies and time scales, and spectral subtraction has a problem with music noise, which affects the denoising performance. In this paper, the Spectral Subtraction (SS) filter and DWT speech enhancement methods are combined to deal with problem faced by DWT selective thresholding techniques against noise of different frequencies and time scales and the musical noise faced by the spectral subtraction filter. We first used spectral subtraction to reduce average noise intensity and then added DWT thresholding for reducing the background noise further. The contemporary methods evaluated using English speech signals taken from CSTR VCTK Corpus database. The objective metrics used to evaluate proposed speech enhancement systems are MSE, SNR, PESQ, and STOI. The proposed speech enhancement algorithm is applied for noise reduction and then compared with conventional algorithms. Experimental results prove that using of the proposed speech enhancement algorithm reduces background noise, improves the SNR of an original speech signal, and improves the final noise reduction performance.
Laparoscopic Anatomical Segment 5 Resection for Hepatocellular Carcinoma Using the Glissonian Approach with Indocyanine Green Dye Fluorescence and Ultrasound guidance
Authors: Siqin Tana , Liu Yue , Meng Xuan , Rong Weiqi , Wang Hongguang 
Published: April 2024

Abstract

Background
Laparoscopic hepatectomy requires precise techniques for safe completion. We have developed flow and modular strategies using visualization technology to improve surgical outcomes.
Methods
Between January 1, 2020, and January 1, 2022, 26 patients with tumors in segment 5 underwent Laparoscopic anatomical segment V resection at our institute using real-time ICG fluorescence mapping and ultrasound guidance. Their perioperative course and operative techniques were reviewed retrospectively.
Result
No cases required open surgery. Blood loss ranged from 10–600 ml, with a median operative time of 225 minutes (90–370). 26 out of 26 preoperative 3D simulations were accurately replicated during surgery, resulting in a 100% concordance rate. Postoperative mortality was absent, with 2 patients experiencing complications leading to a major morbidity rate of 4.6% based on the Clavien‒Dindo classification. Liver function remained stable before and after the operation.
Conclusion
Laparoscopic segment V resection for hepatocellular carcinoma using the Glissonian approach with indocyanine green dye and ultrasound guidance is safe, convenient, and feasible.
Process and mechanism of preparing metallized blast furnace burden from metallurgical dust and sludge
Authors: Gao Xing , Chai Yifan , Wang Yici , Luo Guoping , An Shengli , Peng Jun 
Published: April 2024

Abstract

Metallurgical dust and sludge are solid waste resources with recycling value. In recent years, rotary hearth furnace has become the most important means to treat metallurgical dust and sludge because of its wide range of raw materials and strong treatment capacity. In this study blast furnace ash and OG sludge were selected as the research objects, and high-quality metallized pellets were prepared based on the rotary hearth furnace process. The strength changed of pellets, the reduction process of iron oxides and the removal process of zinc during the roasting of pellets in rotary hearth furnace were studied. To explore the reasonable roasting condition for preparing metallized pellets in rotary hearth furnace. The optimum roasting temperature of the pellets was 1250℃ and the roasting time was 25 min. The compressive strength, metallization rate and dezincification rate of metallized pellets reached 1361N, 97.44% and 95.67%, respectively. The efficient resource utilization of various metallurgical dust and sludge is realized.
Effects of soil structure and hydrodynamic properties on the growth of Camellia sinensis in the main producing areas of the Qinba Mountains
Authors: Zhao Yutong , Xu Zengguang , Zhang Yang , Han Jichang , Li Rui , Chen Tianqing , Niu Ziru , He Peng 
Published: April 2024

Abstract

To enhance the soil hydrological properties of tea plantations, this study applied the Van-Genuchten model to assess various parameters, including the soil water characteristic curve, specific water capacity curve, soil porosity, and particle mechanical composition in the primary tea-producing areas of the Qinba Mountain region. Relationships among soil water retention capacity, water release properties, unsaturated hydraulic conductivity, soil water diffusivity, and porosity across different tea plantation growth zones were investigated. Analysis revealed that the soil texture of the four distinct growth regions in the Qinba Mountain area tea plantations is predominantly silty loam. In areas with poor growth, both water content and bulk density were significantly higher compared to other growth regions, while sand content, organic matter, and porosity were lowest. Conversely, luxuriant growth areas exhibited the highest sand content and lowest silt content, presenting an inverse pattern to that of poor growth areas. The soil moisture characteristic curve was accurately fitted using the V-G model with an R2 value exceeding 0.99. Additionally, the index K(x) = a*exp(b*x) effectively described water suction and unsaturated hydraulic conductivity, yielding an R2 value exceeding 0.90. Soil volume moisture content and soil water diffusivity were adeptly modeled by the exponential function D(θ) = aebθ, with an R2 value surpassing 0.99. Across the total suction range, water holding capacity ranked as follows: poor growth > moderate growth > well growth = luxuriant growth. Optimal water release capacity was observed in poor growth areas, contrasting with the least favorable performance in well growth areas. The ranking of unsaturated hydraulic conductivity across the four regions was as follows: luxuriant growth, well growth, moderate growth, and poor growth. Furthermore, soil water diffusivity exhibited a gradual increase with rising soil volume moisture content, approaching infinite increase when volume moisture content neared saturation.