bluuebunny/crossref_metadata_2025_split huggingface dataset:
[EMIM] [OAc]: An Efficient Ionic Liquid Medium for the Synthesis of
New 4-(furan/pyrrole/thiophene-2-yl)-3, 4-dihydro-1H-chromeno [4,3-d]
pyrimidine-2,5-diones and Molecular Docking Studies
Authors: Pullagura Siva Prakash , Thiriveedhi Arunkumar , Battula Venkateswara Rao , Akula Raghunadh , Begum Ahil Sajeli , Pulla Sai Lakshmi Soukya 
Published: March 2024

Abstract:
An efficient synthesis of Chromeno[b]pyrimidine derivatives 4 has been achieved by treating
4-hydroxy-2H-chromen-2-one 1, furan-2-carbaldehyde / 1H-pyrrole-2-carbaldehyde/ thiophene-2-
carbaldehyde 2, and urea/thiourea 3 at 65-70 °C for 90-120 min using 1-Ethyl-3-methylimidazolium
acetate as ionic liquid and medium with good yields 86-90%. This synthetic method has numerous
advantages, including high yields, a simple protocol, environmental friendliness, brief reaction times,
and mild reaction conditions. Using a catalytically active ionic liquid as the medium eliminates the
need for a catalyst and a solvent. In this study, the docking score of the synthesized compounds was
found to be between -8 to -9 kcal/mol similar to the co-crystal. Additionally, the compounds maintained
their amino acid interactions with Tyr 281 (coagulation protein; 6WV3) and Thr 179 (tubulin
polymerization protein; 5LYJ.pdb).
MR Diffusion-Weighted Imaging in Evaluating Immediate HIFU Treatment
Response of Uterine Fibroids
Authors: Cui Yunneng , Zhang Jing , RAO Jiaming , Feng Minqing , Yao Liangfeng , Liao Weibin , Liang Cuishan , Huang Yanping 
Published: March 2024

Background:
Nowadays, High Intensity Focused Ultrasound (HIFU) is a common surgery option for the treatment of uterine fibroids in China, the immediate
response of which is clinically evaluated using Contrast Enhanced (CE) imaging. However, the injection of gadolinium with its potential adverse
effect is of concern in CE and therefore, it deserves efforts to find a better imaging method without the need for contrast agent injection for this
task.

Objective:
To assess the role of diffusion-weighted imaging (DWI) in evaluating the immediate therapeutic response of HIFU treatment for uterine fibroids in
comparison with CE.

Methods:
68 patients with 74 uterine fibroids receiving HIFU treatment were enrolled, and immediate treatment response was assessed using post-surgical
DWI images. Semi-quantitative ordinal ablation quality grading and quantitative nonperfusion volume (NPV) measurement based on DWI and CE
imaging were determined by two experienced radiologists. Agreement of ablation quality grading between DWI and CE was assessed using the
weighted kappa coefficient, while intraobserver, interobserver and interprotocol agreements of NPV measurements within and between DWI and
CE were evaluated using the intraclass correlation (ICC) and Bland-Altman analysis.

Results:
Grading of immediate HIFU treatment response showed a moderate agreement between DWI and CE (weighted kappa = 0.446, p < 0.001). NPV
measured in 65 fibroids with DWI of Grade 3~5 showed very high ICCs for the intraobserver and interobserver agreement within DWI and CE (all
ICC > 0.980, p < 0.001) and also for the interprotocol agreement between DWI and CE (ICC = 0.976, p < 0.001).

Conclusion:
DWI could provide satisfactory ablation quality grading, and reliable NPV quantification results to assess immediate therapeutic responses of
HIFU treatment for uterine fibroids in most cases, which suggests that non-contrast enhanced DWI might be potentially used as a more costeffective
and convenient method in a large proportion of patients for this task replacing CE imaging.
Chyawanprash: A Trending Ayurvedic Product in the Modern
Healthcare
Authors: Singh Amrat Pal , Anurag  , Saifi Alimuddin , Sharma Alok 
Published: March 2024

Abstract:
Ayurveda is a comprehensive part of the ancient Indian medicine system and is considered
the different classical remedies to treat numerous diseases. According to Ayurveda, the
diet consumed should contain nutritious particulars that have the ability to prevent diseases and
foster a healthy lifestyle. Rasayana Shastra (branch of Ayurveda) encompasses a range of specialised
treatments aimed at extending life, avoiding ageing and illnesses, decreasing degenerative
processes, and maintaining good health. Chyawanprash is unquestionably the most popular
of all rasayana formulations. For ages, it has been used as a supplement to maintain health and
improve immunity and longevity. It is a powerful health supplement composed of over forty
herbs that have been a part of the Indian diet before the arrival of antioxidant supplements, vitamins,
and minerals. Recently, there has been a switch to plant-based derived products and ancient
systems due to an increase in global acceptance. The present challenges in the re-emerging
of Chyawanprash-based function food have been reviewed. Despite a large number of research
reports that have appeared for decades, ancient recipes, methods of preparations, scientific validation,
traditional uses, bioactive compounds, and pharmacological properties of Chyawanprash
and clinical evidence are some major lacking. Further quality assessments are required to establish
the mechanism of action of the standardized Chyawanprash functional food and nutraceuticals
toward the roles of the bioactive(s) in health.
Medicinal Plants and Natural Antioxidants Effective Against Corona: A Systematic Review
Authors: Razmjoue Damoun , Pirhadi Mohadeseh , Bahmani Mahmoud 
Published: March 2024

Background:
Coronavirus disease 2019 or COVID-19 is a type of acute respiratory syndrome
caused by a virus from the family of coronaviruses that has affected all the countries of the
world in a short period.

Objective:
The purpose of this review is to identify and report medicinal plants effective against
covid-19. In this study, the keywords containing medicinal plants and "corona disease" i.e. covid-19,
MERS, SARS-CoV-2, and medicinal plants or natural antioxidants were used.

Methodology:
Search databases including ISI, Scopus, Science Direct, Google Scholar, Mag Iran,
and SID were used. Relevant articles were selected and unrelated articles were excluded.

Results:
Based on the obtained results, medicinal plants such as Isatis indigotica Fortune, Bupleurum
spp., Curcuma longa L., Cibotium barometz (L.), Rheum palmatum L., Rheum palmatum L., Sprag,
Scutettaria baicalensis Georg, Alnus japonica (Thunb.) Steud, Camellia sinensis (L.) Kuntze, Salvia
miltiorrhiza Bunge, Paulownia tomentosa (Thunb.) Steud. Salvia miltiorrhiza Bunge, Tribulus terrestris
L, Broussonetia papyrifera (L.) Vent., Stephania tetrandra S. Moore and related species,
Sambucus formosana Nakai, Strobilanthes cusia, Lycoris radiata, E. purpurea, Lobelia inflata,
Eupatorium perfoliatum, and Achyranthes aspera are the most important medicinal plants that are
used in the treatment of Covid-19.

Conclusion:
Due to having secondary metabolites and antioxidant activity, medicinal plants have a
favorable effect in improving corona symptoms in patients with covid-19.
Analysis of Artifacts and Errors on Intraoral Phosphor Plate Radiographs: A Retrospective Study
Authors: Yurttas Melike 
Published: March 2024

Introduction. The advantages of phosphor plates (PPs), including their flexibility, thinness, and wireless connectivity, have contributed to their widespread use in dentistry alongside the advancement of digital radiography techniques. Continuous use of PPs and certain errors may lead to artifacts on the images. This retrospective study aimed to determine the frequency and types of intraoral PP artifacts.
Methods. This study was conducted on 814 intraoral PP radiographs, including periapical and bitewing images. The errors and artifacts were classified into 4 main categories: technical errors, plate-related artifacts, scanner-induced artifacts, and ambient light artifacts.
Results. A total of 656 periapical and 158 bitewing radiographs were examined. The most observed artifacts on the radiographs were plate-related artifacts, followed by technical errors (n=542, n=461, respectively). Within the category of plate-related artifacts, the most common artifacts were cracks or scratches (n=418, 77.1%), while within the category of technical errors, these were cone-cut errors (n=188, 40.7%). Parallel or zigzag radiopaque lines were the most common scanner-induced artifacts (n=313, 98.7%) and fading was the most common ambient light artefact (n=93, 49.2%). On more than half of the PPs, more than one artifact group was observed.
Conclusions. Cone-cut, cracks/scratches, parallel zigzag radiopaque lines, and fading were common PP artifacts and errors in this study. The analysis revealed that over half of the PPs exhibited appearance of more than one artifact group. The high frequency of artifacts poses a risk of incorrect and incomplete diagnoses in radiographs, emphasizing the crucial importance of understanding the causes and developing effective prevention strategies for artifacts to enhance the reliability of diagnostic imaging and ensure the accuracy of patient assessments.
Risk and Uncertainty Consideration in the Practice of Lean Production
Authors: Sysoeva E. A. , Khoroshilova T. I. 
Published: March 2024

The purpose of the study is to consider the concepts of "risk" and "uncertainty" in the innovative processes of the enterprise in the practic e of lean production. The objectives of the study are to identify the essence of innovation risks, to consider the conceptual apparatus of risks and decision-making in conditions of uncertainty, to consider the components of uncertainty, to give an example of uncertainty and the behavior of the company in this context. Methodology. In this study the following research methods were used: analysis of theoretical materials, synthesis and generalization of literature, as well as classification, description and comparison. Results. The classification of innovation risks is developed, the differences between such concepts as "risk" and "uncertainty" are considered, the types of uncertainty and the algorithm for assessing innovation risks and uncertainties are studied, the experience of using lean production tools, accompanied by risks and uncertainty, is considered. Conclusions. Implementing lean production in an industrial enterprise can be a challenging task. However, if risks are taken into account and adequately managed, lean production can bring significant benefits in the form of increased efficiency, reduced costs and improved quality of products or services. Uncertainty is an integral part of the innovation sphere of the economy. Companies that competently manage uncertainty and are ready to adapt to changes have a better chance of success in innovation business.
Cognitive Modeling of Cargo Port Risk Management
Authors: Bondareva I. O. 
Published: March 2024

Рurpose of research. Increasing the efficiency of cargo port business processes through the use of risk management technology based on the application of a cognitive modeling.Methods. A cognitive modeling of cargo port risk management is proposed, based on a comprehensive step-by-step application of the concept of multi-level goal setting, which involves a thorough elaboration of the cargo port's goals, as well as indicators for assessing the achievability of goals by developing a balanced scorecard (BSS) and constructing a logicalprobabilistic (LP) model; a logical-ontological model developed on the basis of the connections established by the LP model; a simulation model used to check recommendations for adjusting the elements of the system under consideration, developed on the basis of queries to the ontological model, in order to select the most acceptable options for recommendations or combinations thereof and formulate management decisions based on them. Results. Based on the formulated purpose of the study and the assigned tasks, a concept of cognitive modeling was developed, which involves the use of knowledge about the connections between risks, goals, indicators for assessing port activities, as well as clarifying coefficients and the nature of their influence on each other in order to develop recommendations for managing the risks of a cargo port at based on queries to the ontological model. The simulation model within the framework of the proposed conceptual approach allows us to develop management decisions on adjusting the operational components of the system in order to prevent risk situations in the long term (at the tactical and strategic levels) taking into account the influence of external factors. Cognitive modeling is based in this work on the integration of logical-probabilistic, logical-ontological and simulation modeling. Conclusion. As a result of the implementation of the set goals and objectives, a cognitive model of cargo port risk management was proposed. This model combines various types of modeling and takes into account different levels of management. As a result of experiments with a simulation model, the most effective recommendations generated based on a query to the ontological model are selected as management decisions.
Mobile Health Apps, Family Caregivers, and Care Planning: Scoping Review
Authors: Kelley Marjorie M , Powell Tia , Camara Djibril , Shah Neha , Norton Jenna M , Deitelzweig Chelsea , Vaidy Nivedha , Hsiao Chun-Ju , Wang Jing , Bierman Arlene S 
Published: March 2024

Background
People living with multiple chronic conditions (MCCs) face substantial challenges in planning and coordinating increasingly complex care. Family caregivers provide important assistance for people with MCCs but lack sufficient support. Caregiver apps have the potential to help by enhancing care coordination and planning among the health care team, including patients, caregivers, and clinicians.

Objective
We aim to conduct a scoping review to assess the evidence on the development and use of caregiver apps that support care planning and coordination, as well as to identify key factors (ie, needs, barriers, and facilitators) related to their use and desired caregiver app functionalities.

Methods
Papers intersecting 2 major domains, mobile health (mHealth) apps and caregivers, that were in English and published from 2015 to 2021 were included in the initial search from 6 databases and gray literature and ancestry searches. As per JBI (Joanna Briggs Institute) Scoping Review guidelines and PRISMA-ScR (Preferred Reporting Items for Systematic Reviews and Meta-Analyses Extension for Scoping Reviews), 2 authors independently screened full texts with disagreements resolved by a third author. Working in pairs, the authors extracted data using a pilot-tested JBI extraction table and compared results for consensus.

Results
We identified 34 papers representing 25 individual studies, including 18 (53%) pilot and feasibility studies, 13 (38%) qualitative studies, and 2 experimental or quasi-experimental studies. None of the identified studies assessed an intervention of a caregiver app for care planning and coordination for people with MCCs. We identified important caregiver needs in terms of information, support, and care coordination related to both caregiving and self-care. We compiled desired functionalities and features enabling apps to meet the care planning and care coordination needs of caregivers, in particular, the integration of caregiver roles into the electronic health record.

Conclusions
Caregiver needs identified through this study can inform developers and researchers in the design and implementation of mHealth apps that integrate with the electronic health record to link caregivers, patients, and clinicians to support coordinated care for people with MCCs. In addition, this study highlights the need for more rigorous research on the use of mHealth apps to support caregivers in care planning and coordination.
Quantitative Analysis of Isometric Ankle Torque and Muscle Activity during Dorsiflexion and Plantarflexion
Authors: A. Almasiri Osamah A. , Buniya Ali K. , Abdul-Ameer Hussam K. 
Published: March 2024

الخلاصة
تعتبر حركات القدم والكاحل ، مثل الثني الظهري (رفع القدم لأعلى) والثني الأخمصي (توجيه القدم لأسفل) ، أساسية لمجموعة من الأنشطة اليومية مثل المشي والجري والحفاظ على التوازن. حيث تعتمد الميكانيكا الحيوية المناسبة في هذه الحركات على تنسيق عالي بين لكل عضلة حول مفصل الكاحل.
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في هذا البحث تم التحقق من العلاقة بين عزم دوران الكاحل متساوي القياس والنشاط العضلي لعظلة الظنبوب الأمامية وعضلة الساق البطنية أثناء الثني الظهري والثني الأخمصي. اشتملت الدراسة على ثمانية أشخاص أصحاء ، وتم استخدام قياس النشاط الكهربي للعضلة السطحي (sEMG) لتسجيل نشاط العضلات. أظهرت النتائج أن عزم الكاحل كان أعلى أثناء الانثناء الأخمصي مقارنة بالانثناء الظهري. علاوة على ذلك ، أظهر عضلة الظنبوب الأمامية نشاطًا عضليًا أكبر أثناء الانثناء الظهري ، بينما أظهر عضلة الساق البطنية نشاطًا أعلى أثناء الثني الأخمصي. تلقي هذه النتائج الضوء على الميكانيكا الحيوية للكاحل ولما لها من آثار محتملة على التدخلات السريرية واستراتيجيات إعادة تأهيل القدم. هذه الدراسة تعطي تبريرا كافية لإجراء مزيد من البحث حول أدوار عضلات الثني الأخرى في حركات الكاحل للحصول على رؤى شاملة حول تنشيط العضلات وعزم دوران الكاحل متساوي القياس.
Rationale for Embedding Soft Skills in Teaching and Assessment in Higher Learning Institutions
Authors: SANGA PHILIPO 
Published: March 2024

The digital age has witnessed the educational systems preparing students for employability with 21st-century skills, which comprise skills and abilities for success in society and the workplace. To this effect, one of the most significant discussions in higher education in Tanzania and elsewhere is the quality of university graduates. Graduates demonstrate deficiencies in mastery of essential competencies referred to as soft skills. Universities can play a significant role in soft skills development, but implementation in the classroom has faced diverse challenges that have obstructed effective teaching and assessment. One alternative solution is embedding soft skills within the extant program curricula because the academic infrastructure is already in place, so few additional resources may be required. Guided by attribution theory, this paper presents findings from the thematic analysis of semi-structured in-depth interview responses from university teacher educators working with a public university. By and large, the paper unveils that teacher educators recommend that soft skills play a fundamental role in shaping graduates’ personalities and enhancing social competencies. Nevertheless, teacher educators find themselves in dilemmas while pursuing teaching and assessment strategies that improve the furtherance of soft skills.
PERAN PENGELOLA POSDAYA AL-BAROKAH DALAM PENGEMBANGAN KEWIRAUSAHAAN MASYARAKAT DESA SEKARWANGI KECAMATAN RAWAMERTA KABUPATEN KARAWANG
Authors: Sadili Dadan , Santika Tika , Dewi Ratna 
Published: March 2024

Tujuan penelitian ini adalah untuk mengungkapkan dan menganalisis data: (1) peran pengelola posdaya Al-barokah dalam pengembangan kewirausahaan masyarakat, dan (2) faktor pendukung dan penghambat pelaksanaan posdaya dalam pengembangan kewirausahaan Desa Sekarwangi Kecamatan Rawamerta Kabupaten Karawang. Penelitian ini menggunakan pendekatan kualitatif dengan metode studi kasus. Teknik pengumpulan data yang digunakan adalah:(1) observasi, (2) wawancara, dan (3) dokumentasi. Hasil penelitian ini menunjukan bahwa: (1) peran pengelola posdaya Al-Barokah Desa Sekarwangi secara umum cukup baik, dapat terlihat dari hasil pengelolaan dari 4 bidang garapan posdaya yaitu pendidikan, kesehatan, ekonomi, dan lingkungan yang mengalami perkembangan dalam motivasi belajar, hidup sehat, berwirausaha, dan produktivitas. (2). faktor pendukung yang muncul adalah adanya motivasi yang tinggi para pengelola dan dukungan dari masyarakat. Sedangkan faktor penghambatnya adalah pengelolaan posdaya dalam bidang pendidikan adalah kekurangan tenaga pendidik di Pendidikan anak usia dini, terbatasnya alat peraga edukatif, gedung masih membagi waktu dengan madrasah. Penghambat pengelolaan bidang ekonomi yaitu kekurangan modal dan belum tertatanya pembukuan administrasi. Bidang kesehatan masih mengalami kendala kekurangan kader serta minimnya sarana dan prasarana
PENINGKATKAN KEMAMPUAN PEMAHAMAN KONSEP MATEMATIS DENGAN MODEL OPEN ENDED BERBANTUAN MEDIA BLOK PECAHAN KELAS IV SD N 2 SURODADI
Authors: Setyanti Zeni , Ratnasari Yuni , Wanabuliandari Savitri 
Published: March 2024

Tujuan dari penelitian ini adalah untuk mendeskripsikan peningkatan pemahaman konsep pecahan peserta didik kelas IV SD 2 Surodadi dengan penerapan model open ended berbantuan media balok pecahan dan mendeskripsikan peningkatan keterampilan mengajar guru. Penelitian ini menggunakan metode penelitian tindakan kelas yang terdiri dari 2 siklus. Variabel terikat dalam penelitian ini adalah keterampilan mengajar guru dan pemahaman konsep matematis, sedangkan variabel bebas dalam penelitian ini adalah model open ended berbantu media blok pecahan. Â Teknik pengumpulan data meliputi teknik wawancara, observasi, tes, dan dokumentasi. Analisis data yang digunakan yaitu analisis data kualitatif dan kuantitatif. Hasil penelitian menunjukkan bahwa; (1) kemampuan pemahaman konsep matematis peserta didik dengan menerapkan model open ended siklus I mencapai 77% dan meningkat pada siklus II dengan rata-rata 81%; dan (2) keterampilan mengajar guru dalam mengelola pembelajaran matematis dengan menerapkan model open ended pada siklus I pertemuan 1 sebesar 65% sedangkan pada siklus II sebesar 70%, dan meningkat pada siklus II pertemuan 1 sebesar 77% serta pada pertemuan 2 sebesar 80%. Kesimpulannya adalah pemahaman konsep matematis peserta didik meningkat dengan menggunakan model open ended berbantuan media blok pecahan dan keterampilan guru dalam mengajar dengan menggunakan model open ended berbantuan media blok pecahan juga mengalami peningkatan.Â
Diversity, Equity, Inclusion and Belonging: Practice Problems of Real Consequence
Authors: Brown-Liburd Helen L. , Ghio Alessandro , Roberts Andrea Alston 
Published: March 2024

SYNOPSIS
This essay sets the stage for the papers in this special issue by illustrating the ongoing challenges related to diversity, equity, inclusion and belonging (DEIB) in accounting. Although DEIB appears to be gaining momentum in the public debate and among accounting firms, marginalized communities still face significant challenges in the workplace. This special issue documents ongoing trends and experiences related to DEIB in both the accounting profession and accounting practice. Numerous practical suggestions pave the way for improving DEIB in accounting and open the dialogue for future research in accounting on DEIB.
Biplot and Procrustes Analysis of Poverty Indicators By Province in Indonesia in 2015 dan 2019
Authors: Ade Eriyen Saputri  , Admi Salma  , Nonong Amalita  , Dony Permana  
Published: March 2024

Poverty is one of the country's problems that the government should overcome. Poverty is influenced by several indicators. The success of a government can be seen from changes in poverty. This study compares the percentage of Indonesia's poverty indicators at the beginning of office (2015) and the end of office (2019) of one government period. The indicators that most affect the poverty rate in 2015 and 2019 are seen using biplot analysis while to measure the similarity and the magnitude of the percentage change in poverty from 2015 to 2019 can use procrustes analysis. The results of the biplot analysis show that households have access to proper sanitation services as the indicator with the highest diversity in 2015 while in 2019 it is the poor young population (15-24 years old) who are not in school and working or attending training and households have access to decent drinking water sources. Riau Islands, DKI Jakarta, DI Yogyakarta, and Bali are the provinces that have the highest values in almost all poverty indicators except the indicator of the percentage of young people (15-24 years old) who are not in school, working or attending training. The results of the procrustean analysis show an increase of 9.7% in Indonesia's poverty indicators in 2019 compared to 2015. So it can be said that the two configurations are very similar.