bluuebunny/crossref_metadata_2025_split huggingface dataset:
Immersion in a relaxing virtual reality environment is associated with similar effects on stress and anxiety as heart rate variability biofeedback
Authors: Pratviel Yvan , Bouny Pierre , Deschodt-Arsac Véronique 
Published: April 2024

Practicing guided breathing at 0.1 Hz in virtual reality yields psychological and physiological benefits. Nonetheless, it remains uncertain whether these effects surpass those induced in a real-world setting. Indeed, the potential influence of the virtual environment on perceived stress and anxiety is not yet fully understood. In this experiment, we aimed to compare the effects of heart rate variability biofeedback combining both haptic and visual cues in real and virtual reality settings among the same group of participants. Additionally, to discern whether the psychological benefits arise from viewing an environment in virtual reality or from the act of performing guided breathing in this specific setting, a “control” immersion condition was introduced. 36 healthy sport students (9 females) participated in this study, performing both the real and virtual reality protocols in a randomized order. Anxiety and stress levels were assessed using the STAI-Y questionnaire and a visual analog scale, respectively. Physiological effects were assessed through measures of heart rate variability, and the performance of cardiac coherence was compared between the real and virtual implementations of guided breathing. As expected, both real and virtual reality heart rate variability biofeedback led to similar physiological modulations and cardiac coherence performances. A decrease in stress and anxiety was observed in both protocols, particularly among participants who initially reported higher stress or anxiety levels. However, no additional changes in psychological states were observed when performing guided breathing while immersed in the virtual environment.
Chitogel with deferiprone following endoscopic sinus surgery: improved wound healing and microbiome
Authors: Megow Anna , Bouras George , Alsuliman Yazeed , Cooksley Clare , Vyskocil Erich , Murphy William , Vreugde Sarah , Wormald Peter-John 
Published: April 2024

BackgroundAdhesion formation, sinus ostial narrowing, and presence of pathogenic bacteria are associated with poor outcomes following endoscopic sinus surgery (ESS) for chronic rhinosinusitis. Chitogel has been shown to improve wound healing, restore a healthier microbiome, and reduce post-operative infections post ESS. Deferiprone has antibacterial properties and has been shown to reduce adhesion formation. The aim of the study was to assess whether the addition of low concentration deferiprone to Chitogel further improves surgical outcomes following ESS compared with Chitogel alone.MethodsIn this double-blinded trial, 45 patients undergoing ESS were prospectively recruited. At the end of the surgery, patients were randomised to receive Chitogel alone, Chitogel with 1 mM of deferiprone, or Chitogel with 5 mM of deferiprone to one side of the sinuses (allowing the other side to serve as control). Patients underwent routine follow-ups with symptom questionnaires and nasoendoscopies performed at 2, 6, and 12 weeks post-operatively. Sinus ostial measurements, microbiology, and microbiome swabs from bilateral middle meatuses were collected intraoperatively and at 12 weeks post-operatively.ResultsA significant improvement in the endoscopic appearance of the sinuses and frontal ostial patency was noted at 12 weeks post-operatively (p &lt; 0.05) in all three treatment groups compared with the control. There was no significant difference noted between patients who received Chitogel alone and those who received Chitogel with 1 or 5 mM deferiprone.ConclusionChitogel alone, Chitogel with 1 mM deferiprone, and Chitogel with 5 mM deferiprone used following ESS led to a significant improvement in endoscopic appearance of the sinuses and frontal ostial preservation at 12 weeks post-operatively. No significant difference was found with the addition of deferiprone to Chitogel.
New-onset organ dysfunction as a screening tool for the identification of sepsis and outcome prediction in dogs with systemic inflammation
Authors: Ciuffoli Elena , Troìa Roberta , Bulgarelli Cecilia , Pontiero Alessandra , Buzzurra Francesca , Giunti Massimo 
Published: April 2024

IntroductionSepsis in people is defined as a life-threatening organ dysfunction (OD) caused by a dysregulated host response to infection. In veterinary medicine, sepsis is still defined by the presence of systemic inflammation plus the evidence of infection. Based on recent veterinary studies, multiorgan dysfunction syndrome (MODS) has been associated with a worse outcome in sepsis. Thus, the screening for OD is warranted to identify the most critically ill patients. The aim of this study was to investigate the diagnostic value of new-onset OD for the prediction of sepsis and outcome in a population of critically ill dogs with systemic inflammation.Materials and methodsDogs admitted to the Emergency Room and/or the Intensive Care Unit with systemic inflammation, defined by a serum C-reactive protein concentration &gt; 1.6 mg/dL, were retrospectively included. Enrolled dogs were categorized according to the presence of sepsis or non-infectious systemic inflammation. The presence of newly diagnosed OD was assessed based on criteria adapted from human literature and previously reported canine criteria.Results275 dogs were included: 128 had sepsis and 147 had non-infectious systemic inflammation. The frequency of new-onset OD was not different between these groups. Only the presence of fluid-refractory hypotension was significantly associated with a diagnosis of sepsis (OR 10.51, 3.08–35.94; p &lt; 0.0001). The frequency of at least two ODs was significantly higher in non-survivors compared to survivors, according to both the human and the veterinary criteria considered for the study (p = 0.0001 and p = 0.0004, respectively). Specifically, the presence of acute kidney injury, stupor or coma, prolonged Prothrombin Time and decreased Base Excess were associated with a higher risk of death in the multivariate binary logistic regression.DiscussionIn this population of critically ill dogs with systemic inflammation, the detection of newly diagnosed ODs was not able to predict sepsis diagnosis, other than the presence of fluid-refractory hypotension. However, given the strong prognostic significance associated with ODs, our results support the early screening for ODs in any severe inflammatory critical care condition to identify high-risk patients and optimize their management.
How does chronic pain impact the lives of dogs: an investigation of factors that are associated with pain using the Animal Welfare Assessment Grid
Authors: Malkani Rachel , Paramasivam Sharmini , Wolfensohn Sarah 
Published: April 2024

IntroductionChronic pain can profoundly affect the wellbeing of dogs and our understanding is limited regarding the multidimensional impact it has on dog quality of life. This study aimed to assess the factors that are significant and predictive of chronic pain in dogs using the Animal Welfare Assessment Grid (AWAG) to further understand what factors influence their welfare.MethodsSeventy six AWAG assessments were undertaken across 46 dogs that clinicians diagnosed as having musculoskeletal conditions that caused chronic pain. Wilcoxon-rank sum tests were used to assess the difference in scores between dogs with chronic pain and a cohort of healthy dogs (n = 143).ResultsAll physical factors besides body condition, and all psychological, environmental, and procedural factors were significantly different between healthy dogs and dogs with chronic pain, evidencing how chronic pain impacts all domains of a dog’s life. Spearman Rank Correlation Coefficient (RS) revealed several significant strong positive correlations such as the association between the severity of clinical symptoms with poorer mobility and the frequency at which the dog experienced fearful stimuli. Logistic regression showed that fears and anxieties frequency, the dog’s reaction to stressors, engagement with enrichment, and social interactions were significant predictors of chronic pain in dogs.DiscussionThis highlights that typical signs of musculoskeletal disorders such as gait changes, stiffness, lameness might manifest after behavioral changes such as increased fearfulness, prolonged recovery from a stressful event, a reduced interested in social interactions, toys or play. Owners only seeking veterinary attention when the presence of physical signs of disease are evident may result in a delayed veterinary attention resulting in reduced welfare. Regular veterinary assessments combined with use of the AWAG can proactively identify these behavioral indicators and result in prompt treatment and improved quality of life.
Prospects for the Use of Mesenchymal Stem Cells of the Olfactory Laying in the Treatment of Allergic Rhinitis and Chronic Polyposis Rhinosinusitis: A Literature Review
Authors: Шулепова Э.А. , Ниделько А.А. , Мантивода В.Э. , Антоневич Н.Г. , Гончаров А.Е. , Чекан В.Л. , Гребень Н.И. , Шестакова Е.В. 
Published: April 2024

В статье представлен обзор литературы, основанный на поисковых базах Medline, Embase, PubMed, научной электронной библиотеке eLibrary, с момента их создания до 31 мая 2023 г. Клеточные технологии являются перспективными в лечении хронических неинфекционных заболеваний полости носа, таких как аллергический ринит и хронический полипозный риносинусит. Использование терапии на основе мезенхимальных стволовых клеток приводит к снижению продукции провоспалительных цитокинов, подавлению иммунного воспаления и стимуляции регенерации тканей в месте их введения. Мезенхимальные стволовые клетки способны распознавать поврежденный участок и индуцировать иммунный ответ как врожденного, так и адаптивного иммунитета в случае недостаточного иммунного ответа. С другой стороны, они подавляют функцию иммунных клеток, если в поврежденном участке формируется избыточная иммунная реакция. Таким образом, в зависимости от уровня секреции факторов воспалительной среды мезенхимальные стволовые клетки проявляют либо провоспалительную, либо противовоспалительную функцию. Дальнейшее изучение иммунных процессов при хронических неинфекционных заболеваниях полости носа будет способствовать появлению новых, более эффективных методов лечения, основанных на клеточной терапии.
The article presents a literature review based on the Medline, Embase, Pubmed search databases, eLibrary scientific electronic library from the moment of their creation until May 31, 2023. Cellular technologies are promising in the treatment of chronic non- communicable diseases of the nasal cavity such as allergic rhinitis and chronic polypous rhinosinusitis. The use of mesenchymal stem cells leads to a decrease in the production of pro-inflammatory cytokines, suppresses immune inflammation and stimulates tissue regeneration at the injection site. Mesenchymal stem cells are capable of recognizing a damaged site and inducing an immune response of both innate and adaptive immunity in case of an insufficient immune response. On the other hand, they suppress the function of immune cells if an excessive immune response forms in the damaged area. Thus, depending on the level of secretion of inflammatory environment factors, mesenchymal stem cells exhibit either pro-inflammatory or anti-inflammatory functions. Further study of immune processes in chronic non-communicable diseases of the nasal cavity will contribute to the emergence of new, more effective methods of treatment based on cell therapy.
Digitalisasi Bisnis dalam Strategi Pemasaran Maggot BSF pada Agribisnis Anak Nagari dengan Metode Fuzzy Mamdani
Authors: Harma Wahri , Hadi Febri , Kartika Devia 
Published: April 2024

Berkembangnya teknologi pada saat ini sangat dirasakan oleh seluruh aspek kehidupan. Salah satu aspek kehidupan yang mempunyai dampak perkembangan teknologi adalah aspek ekonomi. Ruang lingkup dari aspek ekonomi yaitu dalam melakukan pemasaran dari sebuah bisnis. Untuk meningkatkan pemasaran bisnis diperlukan teknologi informasi yang dikenal dengan digitalisasi. Digitialisasi bisnis sangat diperlukan dalam kegiatan agribisnis anak nagari nagari Muaro Paiti, Kec. Kapur IX, Kab. Lima Puluh Kota. Kegiatan agribisnis anak nagari ini adalah budidaya Maggot BSF (Black Soldier Fly). Strategi pemasaran Maggot BSF ini menggunakan metode fuzzy mamdani. Metode fuzzy mamdani sering dikenal dengan metode max-min. Tujuan dari penelitian ini adalah untuk meningkatkan penjualan Maggot BSF Agribisnis Anak Nagari dan menentukan permintaan pasar dan berapa banyak Maggot BSF harus di produksi. Data yang digunakan dalam penelitian ini merupakan data produksi Maagot BSF yang diambil dari periode Agustus 2021 sampai dengan Januari 2022. Hasil dari penelitian menggunakan metode Fuzzy Mamdani dapat memberikan prediksi produksi Maggot BSF sehinggga pemasaran Maggot BSF dapat diberikan kepada konsumen
Corps énergétique et danse
Authors: Villard Marie-Aline 
Published: April 2024

Penser le « corps énergétique » et la danse revient à considérer cette réalité énergétique au sein du corps dansant, autant au niveau quantitatif que qualitatif. En danse, nous ne parlons pas exactement de « corps énergétique », mais principalement d’énergie déployée. Afin de comprendre le « corps énergétique » en danse, nous nous sommes intéressés à deux pratiques originales mettant en œuvre un jeu de question-réponse énergétique : le contact improvisation et le vol chorégraphique. Le corps énergétique apparaît au fur et à mesure de la réflexion comme une métaphore désignant une triade nécessaire au déploiement d’un seul système, et c’est cette même triade que nous rencontrons à chaque fois que nous appréhendons la complexité du corps dansant.
De l’importance de l’imaginaire dans le dialogue « science-société »
Authors: Chifflet Stéphanie 
Published: April 2024

Les enjeux des sciences et des techniques ne peuvent être saisis dans toute leur complexité sans une prise en compte préalable du rôle de l’imaginaire dans la pensée de l’homme et dans son être-au-monde. Le rapport de l’homme aux savoirs scientifiques et techniques est composé d’images et de récits mythiques plus ou moins conscients. Débattre de l’orientation que nous souhaitons donner aux recherches et aux innovations scientifiques nécessite de considérer sérieusement l’irrationalité humaine. C’est en saisissant cette logique autre (l’« alogique »), les rêveries parfois indicibles, les peurs persistantes, que le dialogue « science-société » pourra être ouvert et constructif.
L’analyse contrastive : contours et limites d’une approche mythocritique confrontant le Genji Monogatari de Murasaki Shikibu et les Lais de Marie de France
Authors: Bruno-Meylan Stéphanie 
Published: April 2024

Dans le cadre de notre thèse, nous avons confronté les Lais de Marie de France datant du xiie siècle qui présentent la particularité alors inédite d’avoir pour auteur une femme et le Genji Monogatari de Murasaki Shikibu (une femme également), écrit au xie siècle au Japon, qui fait aussi figure d’exception dans un paysage scriptural majoritairement masculin, a fortiori pour une œuvre d’une telle ampleur. Le rapprochement entre les deux œuvres était avant tout motivé par une thématique de fond, l’imaginaire féminin, déployé dans deux cultures géographiquement et sociologiquement éloignées, cependant immergées dans un milieu élitiste, celui de la Cour. Ce choix s’inscrivait surtout dans la perspective d’une approche mythocritique plutôt que strictement littéraire, dont l’intérêt se situait en deçà du cadre du texte, puisqu’il puisait dans la mythologie fondatrice des deux cultures, source de l’émergence d’un imaginaire féminin à des époques chiches de féminité. Or, cette analyse, que nous avons qualifiée de contrastive, a permis l’ouverture de la réflexion sur d’autres perspectives que seul autorisait un tel rapprochement ; elle a également cherché à distinguer, parmi les motifs communs aux deux textes, ceux qui relevaient d’une universalité (contextuelle) de ceux qui relevaient d’une commune origine eurasiatique. La réflexion était axée sur la notion d’altérité selon une acception très large mais concentrée sur la représentation par l’imaginaire féminin de l’Autre sexe et d’un Ailleurs avant tout textuel et narratif.
La couronne et la sépulture, ou la naissance du culte de saint Adalbert de Prague en Pologne médiévale
Authors: Salmon-Siama Monika 
Published: April 2024

Cet article a pour objectif de présenter, en se basant sur l’exemple de la naissance du culte de saint Adalbert, évêque de Prague, comment le mythe hagiographique évolue dans le paysage idéologique et culturel de la Pologne aux alentours de l’an mil. À travers la mise en relief de plusieurs événements symboliques qui marquent la reconnaissance officielle de la sainteté du martyr, décapité en Prusse en 997, il est question de s’interroger sur l’évolution de l’imaginaire religieux à cette époque d’acculturation chrétienne, afin de comprendre pourquoi le patronage dynastique et patriotique a été attribué à saint Adalbert en Pologne médiévale.
De quelques nombres dans la tradition celtique
Authors: Jouët Philippe 
Published: April 2024

Pour expliquer les nombres et leurs occurrences dans la tradition celtique (mythes, représentations, realia), plutôt que de les relier dans le cadre de la numérologie ou de leur donner a priori un sens, il faut analyser l’ensemble du contexte dans lequel ils apparaissent. La plupart de ces nombres sont profondément reliés aux saisons cosmologiques, aux modèles cycliques, et ont des valeurs analogiques et métaphoriques dans plusieurs champs (théories de la sagesse, de la guerre, du corps politique). Ils peuvent être compris comme le fruit d’expériences héritées de la culture indo-européenne, et s’inscrire dans une périodisation à déterminer. Relèvent de cette conception, les Jumeaux divins, les trois cieux, les trois fonctions, le voyage dans l’autre monde, l’organisation quaternaire ou quinaire des lieux. Cet article traite donc des occurrences des nombres en lien avec l’année, conçue comme une image rythmique de la puissance.
Eco-humanism in Kiran Desai’s Hullabaloo in the Guava Orchard (1998)
Authors: Le Moine Lydie 
Published: April 2024

Kiran Desai’s novel revolves around several connected issues: the environment, man’s anthropocentric attitude towards nature, eco-criticism and a reappraisal of the binary opposition “nature-culture”, to quote a few. Feminism is also an underlying theme. However, Hullabaloo in the Guava Orchard (1998) is not a novel that would be straightforwardly deemed “ecofeminist” despite its obvious eco-critical stance and its depiction of unconventional women. It rather hints at a peculiar form of eco‑humanism in an allegorical and sometimes derisive tone. Sampath, a likeable dreamer-dubbed-guru by public opinion, and his mother Kulfi, maybe a less-likeable dreamer obsessed with food and one-of-a-kind cooking, allow the reader to look beyond the opposition between nature and culture, to challenge traditional gender roles but also some tenets of ecofeminism in order to suggest another approach to human ecology that would be free from anthropocentrism. While exploring and analysing the characters and the setting, I will explain why it matters that the writer chose to associate Sampath’s access to public fame to “the rumour that Coca‑Cola might soon be arriving in India” (67).
Many Faces of Madness: Mindless Destruction with Snapshots of Preservation
Authors: Sinha Madhumeeta 
Published: April 2024

This article is a brief analysis of two contexts of struggles, and also of celebration of the values of preservation of forests. One of the locations is in the Uttarakhand region well known for the emblematic “Chipko” movement of the 1980s, when women fought the epic battle to protect trees by hugging them. We study the documentary film by Deepa Dhanraj, based on the life of Sudesha Devi one of the leaders whose example brought women together to resist and fight the power of the state. The second location is the state of Jharkhand, which has seen ongoing struggles for conservation over decades. The echoes of the steps of the resistance movement can be heard in the powerful voice of Jacinta Kerketta. The life and work of these two activists present a case for reflection on the imbrication of the personal and the political in the context of social movements.
The Influence of Female Sex Worker Fellows Support and Motivation on Sexually Transmitted Diseases (STDs) Prevention Behaviors in Makassar City, Indonesia
Authors: Zulhijriani Zulhijriani , Lestari Nur Cahyani Ari , Muriana Eviyati Aini , Marlinawati Iin Tri , Setyanti Dian Shofia Reny , Sari Putri Yunita 
Published: April 2024

Background: A sexually transmitted diseases (STDs) is an illness that is primarily transmitted through sexual contact. There are around 30 different species of microorganisms, including bacteria, viruses, and parasites, that can be transmitted through sexual activity without protection. The most prevalent conditions include gonorrhea, chlamydia, syphilis, trichomoniasis, chancroid, genital herpes, HIV, and hepatitis B. Within society, sexually transmitted diseases (STDs) are the most prevalent form of infection.
Aims: The objective of this study is to ascertain the direct and indirect impact on the prevention of sexually transmitted illnesses in the city of Makassar.
Methods: This study used a cross-sectional design. The study collected samples from 45 consenting individuals who agreed to participate. This study used a structure equation model as an analysis method using Smart PLS 2.0.
Results: The findings demonstrated a significant correlation between the support of fellow female sex workers (FSWs) and the practice of STDs prevention, with a direct impact of 10.26%. Additionally, there was a direct influence of STDs prevention behavior on motivation, accounting for 10.84%. Furthermore, the support of fellow FSWs had a substantial impact on motivation, with a direct influence of 29.16%. The overall direct effects have increased by 50.26%. The support of fellow FSWs has an indirect influence on STDs prevention behavior, increasing motivation by 5.77%. The cumulative impact, both direct and indirect, amounts to 56.03%. The Q-Square analysis model accounts for 44.1% of the variability in the data and specifically investigates the phenomenon studied. The remaining 55.9% of variability is attributed to other variables that were not addressed in this study.
Conclusion: Hence, the research findings indicate that various factors, including the assistance from fellow female sex workers and motivation, contribute to the promotion of STDs prevention behavior.

Received: 14 December 2023, Reviewed: 25 December 2023, Revised: 06 January 2024, Accepted: 16 January 2024.