bluuebunny/crossref_metadata_2025_split huggingface dataset:
The epidemiology and phenomenology of non-antipsychotic-induced dystonia: a hybrid systematic-narrative review
Authors: Catthoor Kirsten , Detraux Johan , De Hert Marc 
Published: February 2025

Abstract

Background
Medication-induced dystonia (MID) is a movement disorder (MD), characterized by involuntary sustained or intermittent muscle contractions, causing abnormal, often repetitive, movements, postures, or both. Although MID is commonly associated with the use of antipsychotics, it also occurs with many other medications widely used in clinical practice.

Methods
A systematic literature search (from inception to November 2023), using the PubMed and Embase databases, was conducted without language restriction for articles reporting on MID in people without pre-existing MDs, and this for all potentially relevant non-antipsychotic medications. A narrative synthesis of the available evidence was undertaken.

Results
MID is common (1 to 10%) with certain antiemetics. Selective serotonin reuptake inhibitors and the antiepileptics valproate, carbamazepine, and lamotrigine are rarely (0.01 to 0.1%) or very rarely (<0.01%) associated with MID. All other medications are very rarely (<0.01%) associated with MID or have a risk that cannot be precisely estimated. The actual rate of dystonic reactions with most non-antipsychotic agents remains unknown, owing to misdiagnosis and underreporting in the scientific literature. In general, MID seems to occur more often in children and adolescents, even with a single low dose, and with polymedication. In most cases, MID is acute in onset (occurring within hours to days) and involves the head and neck.

Conclusions
Although MID is most common with dopamine receptor-blocking antiemetics, many other medications may also produce dystonic reactions, particularly in children and adolescents. Although such incidents remain rare, there are indications that MID is underreported for many classes of medications.
Actin from within – how nuclear myosins and actin regulate nuclear architecture and mechanics
Authors: Gawor Marta , Lehka Lilya , Lambert Danielle , Toseland Christopher P. 
Published: February 2025

ABSTRACT
Over the past two decades, significant progress has been made in understanding mechanotransduction to the nucleus. Nevertheless, most research has focused on outside-in signalling orchestrated by external mechanical stimuli. Emerging evidence highlights the importance of intrinsic nuclear mechanisms in the mechanoresponse. The discovery of actin and associated motor proteins, such as myosins, in the nucleus, along with advances in chromatin organisation research, has raised new questions about the contribution of intranuclear architecture and mechanics. Nuclear actin and myosins are present in various compartments of the nucleus, particularly at sites of DNA processing and modification. These proteins can function as hubs and scaffolds, cross-linking distant chromatin regions and thereby impacting local and global nuclear membrane shape. Importantly, nuclear myosins are force-sensitive and nuclear actin cooperates with mechanosensors, suggesting a multi-level contribution to nuclear mechanics. The crosstalk between nuclear myosins and actin has significant implications for cell mechanical plasticity and the prevention of pathological conditions. Here, we review the recent impactful findings that highlight the roles of nuclear actin and myosins in nuclear organisation. Additionally, we discuss potential links between these proteins and emphasize the importance of using new methodologies to unravel nuclear-derived regulatory mechanisms distinct from the cytoskeleton.
Riesgo durante la Lactancia Natural en Trabajadoras Sanitarias … ¿conceden los Tribunales la prestación?
Authors: González Cáceres Ana María , Rosas Molina María José , Mateo García Marco Antonio , Lang-Lenton Ramírez Luis , Suárez Melián Iván , González Cáceres Elda María 
Published: February 2025

La OMS y la Asociación Española de Pediatría (AEP) recomiendan un inicio precoz de la lactancia materna y su mantenimiento el mayor tiempo posible. La prestación por riesgo durante la lactancia natural se introduce en la legislación española con la Ley Orgánica 3/2007 de 22 de marzo y consigue el desarrollo reglamentario en el Real Decreto 295/2009, de 6 de marzo.
Se utiliza el buscador del Centro de Documentación Judicial CENDOJ con las palabras claves: Riesgo durante la lactancia natural y Sanidad.
Se obtienen 10 resultados de los que se excluyen 5 por no corresponder con los criterios de búsqueda.
Se observa que la mayoría de las sentencias estiman las demandas de las trabajadoras. Influye la existencia de una evaluación de riesgos del puesto de trabajo específica para la lactancia. Existe discrepancia entre lo que promulga la OMS y la AEP y los derechos reconocidos en la legislación laboral española.
Riesgo al levantar cargas: mucho más que biomecánica. Investigación con metodología mixta en una pequeña empresa constructora de Colombia
Authors: Gómez salazar Lessby , Sibaja Terán Beatriz , Ordóñez Hernndez Cecilia Andrea , Martinez älvarez Luz América 
Published: February 2025

Objetivo: Evaluar integralmente el riesgo de trastornos musculoesqueléticos asociado al levantamiento de cargas relacionado con los factores biomecánicos en el trabajo en la construcción, y analizar las percepciones y estrategias de afrontamiento de los/as trabajadores/as expuestos.
Métodos: Estudio transversal con un enfoque mixto, cuantitativo y cualitativo. La fase cuantitativa consistió en una evaluación de 8 tareas comunes en la construcción mediante los métodos NIOSH y OWAS. La fase cualitativa incluyó entrevistas en profundidad sobre la percepción del riesgo y formas de afrontamiento, y se analizó el contenido temático.
Resultados: El 62,5% de las tareas evaluadas presentaron niveles de riesgo alto a moderado de lesión musculoesquelética, siendo el paleo y levantamiento de bultos de cemento las de mayor riesgo. Las entrevistas revelaron normalización del riesgo, influencia de factores socioculturales y económicos (precariedad laboral) en la percepción y manejo del riesgo. Se identificaron factores concomitantes para el análisis, como la baja experiencia laboral, el rol de la mujer en el sector, y el estatus migratorio de los trabajadores. Se generó un modelo integrador para el análisis del riesgo.
Conclusiones: El riesgo asociado al levantamiento de cargas en construcción trasciende los aspectos biomecánicos. Factores socioeconómicos, psicosociales, de género y culturales afectan la forma de afrontar el riesgo. Sin mejoras en estos aspectos, los ajustes en los puestos de trabajo no serán suficientes para mitigar el impacto sobre la salud de los/as trabajadores/as y las empresas.
Fair food futures UK: Protocol for a mixed methods study exploring what approaches adopted by community food organisations are more likely to prevent the need for emergency food in two multicultural communities in Northern and Southern England
Authors: Sheard Laura , Previdoli Giorgia , Burton Wendy , Benchekroun Rachel , Power Maddy , Doherty Bob , Hadley Philip , Kapetenaki Ariadne Beatrice , Islam Shahid , Mirza Sairah , Cameron Claire , Pickett Kate , Hutton Angela , Edwards Charlotte , Bryant Maria 
Published: February 2025

Introduction
Food insecurity reduces people’s chances to live healthy and active lives and places a significant burden on healthcare systems. Levels have significantly increased in the UK since 2010, due to the impact of austerity and, more recently, the COVID-19 pandemic and the cost of living crisis. This increase is projected to continue. Households with children are amongst those at highest risk for food insecurity. A variety of community food organisations (CFOs), such as community gardens, community kitchens, food banks and social markets, have been essential in responding to rising food insecurity, including providing emergency food and other types of support such as welfare advice. However, beyond food banks, little is known about differing approaches to food aid in the UK, including how these organisations provide additional services to address the underlying issue that has led someone to seek emergency food support.

Aim
To understand what approaches used by community food organisations are most likely to help prevent the need for emergency food in two multicultural communities in the North (Bradford) and South (Tower Hamlets, London) of England, with high levels of ill-health and food insecurity.

Research design, setting and participants
This is a mixed methods study informed by complex systems theory. Methods include participatory systems mapping and qualitative longitudinal research. We will map the availability and type of help with food, and produce a typology of CFO approaches, using a survey, multiple local and national participatory system mapping workshops and interviews with local and national stakeholders (WP1). Then, we will conduct a longitudinal qualitative research using a ‘researcher in residence’ approach in up to 10 CFOs purposively sampled to reflect the diversity of prevention strategies adopted by CFOs. Research will include: a) a 12 month ethnographic study; b) three waves of ‘go along’ interviews with up to 35 families; and c) a visual study where the same families are invited to share photos and videos about their food thoughts via Indeemo research app.

Outputs and dissemination
Outputs will include: a) a toolkit on CFOs to support local and national policy and implementation decisions, b) a travelling exhibition with visual representations of people’s lived experiences c) publications in academic journals, d) blog posts, e) public talks, and f) policy briefs. Findings will help decision makers to invest in the most accessible, beneficial and culturally appropriate resources for communities.
Patient-Reported Outcomes among people living with Chronic Pruritus (PROs-CP): Protocol for a single-center, multistage, mixed-methods prospective cohort study in Thailand
Authors: Nochaiwong Surapon , Ruengorn Chidchanok , Kiratikanon Salin , Rujiwetpongstorn Rujira , Chieosilapatham Panjit , Tovanabutra Napatra , Chiewchanvit Siri , Awiphan Ratanaporn , Phosuya Chabaphai , Ruanta Yongyuth , Thavorn Kednapa , Chuamanochan Mati 
Published: February 2025

Background
Although there have been well-validated patient-reported outcome (PRO) measurements in dermatology practice, there is limited evidence of the adopted comprehensive aspects of PRO measures in long-term follow-up among people living with chronic pruritus. As such, we aim to create a cohort study of the Patient-Reported Outcomes among people living with Chronic Pruritus (PROs-CP) in Thailand.

Methods and design
This study is a single-center, prospective, open cohort, observational longitudinal study using a multistage, mixed-methods parallel designs to integrate both quantitative and qualitative data regarding PROs among people living with chronic pruritus (itch lasting six or more weeks). The multistage of the PROs-CP study will comprise three sub-studies: (i) study I, PROs measure development, translation, and psychometric validation; (ii) study II, perspectives of people living with chronic pruritus to gain more information regarding disease burden and unmet treatment care responses; and (iii) study III, a longitudinal study to assess the impact of chronic pruritus on long-term health outcomes. Based on a comprehensive review of a panel of stakeholders with chronic skin disease, a set of PRO measurement tools will comprise an established validated Thai version. Meanwhile, meaningful non-Thai versions or unestablished PRO instruments will be translated and developed through this study as appropriate. Quantitative data will be collected based on PRO measures regarding pruritus symptoms and severity, disease activity control and treatment satisfaction, general- and dermatology-specific health-related quality of life, mental health and psychosocial issues, and psychosomatic symptoms. Qualitative data will be obtained from the patient’s perspectives through individual interviews.

Ethics and dissemination
The study protocol was approved by the Ethics Committee of the Faculty of Medicine, Chiang Mai University (MED-2566-0299), Thailand. Our findings will be disseminated through scientific conferences and publications in peer-reviewed journals.

Conclusion
Regarding the mixed-methods approach, this open cohort, prospective longitudinal study will provide an evidence-based better understanding of patient perspectives on chronic pruritus burden and inform the utility of a comprehensive set of PROs to measure their long-term health outcomes.

Trial registration
Thai Clinical Trials Registry (TCTR, thaiclinicaltrials.org) registration TCTR20240327001 (registered on March 27, 2024).
Global solution and blow-up of critical heat equation with nonlocal interaction
Authors: Yang Minbo , Zhang Jian 
Published: February 2025

Abstract
We consider the Cauchy problem of the critical nonlocal heat equation

u
t

-

Δ
⁢
u

=

(

|
x
|

-
μ

∗

|
u
|

2
μ
∗

)

⁢

|
u
|

2
μ
∗

-
2

⁢
u

in
⁢

ℝ
N

×

(
0
,

T
max

)

,

u_{t}-\Delta u=(|x|^{-\mu}\ast|u|^{2^{\ast}_{\mu}})|u|^{2^{\ast}_{\mu}-2}u%
\quad\text{in }\mathbb{R}^{N}\times(0,T_{\max}),

where

N
≥
3

{N\geq 3}

,

0
<
μ
<

min
⁡

{
4
,
N
}

{0<\mu<\min\{4,N\}}

and

2
μ
∗

=

2
⁢
N

-
μ

N
-
2

{2^{\ast}_{\mu}=\frac{2N-\mu}{N-2}}

is the critical exponent in the sense of the Hardy–Littlewood–Sobolev inequality.
The aim of this paper is to study the behaviour of the solutions in time. More precisely, we prove the existence and decay of global solutions and blow-up in finite time.
Furthermore, the global uniform bound of the global solutions in

H
˙

1

⁢

(

ℝ
N

)

{\dot{H}^{1}(\mathbb{R}^{N})}

and the asymptotic behaviour of them are given.
Hazard analysis of future surface displacements on active faults based on the recurrence interval of strong earthquakes
Authors: Zhou Qingyun , Liu Jingnan , Tian Peng , Luo Weidong , Bai Xianfu , Yang Yue , Zou Zhenyu 
Published: February 2025

Abstract
Coseismic surface displacements pose a serious threat to the safety of linear infrastructures on active faults. A reasonable evaluation of surface displacements on active faults is important. Probabilistic fault displacement hazard analysis (PFDHA) is often used for surface displacement evaluation. However, PFDHA, developed based on the classical probabilistic method, requires an in-depth study of the activity parameters of all active faults in seismic–tectonic zones, greatly limiting its application in engineering design. The recurrence interval of strong earthquakes is a readily obtainable parameter of fault activity. In this study, we combine this key parameter with various seismic indicators to develop a comprehensive algorithm to assess potential future surface displacement hazards. In addition, the factors affecting the method are analyzed, and the surface displacements of several earthquakes with a magnitude of 7 or above are compared. The results indicate that the predicted future surface displacements using our method are greater than the true displacements of seismic events. For easy use, the exceedance probability–displacement (horizontal and vertical) curves of 27 strong earthquake recurrence intervals are given. This facilitates structural designers to quickly obtain future displacement values in structural design.
Thermo-hydraulic characteristics of molten salt NaNO3–KNO3 using numerical simulations
Authors: Kudariyawar Jayaraj Y. , Sateesh K.A. 
Published: February 2025

Abstract
Nowadays most of research in nuclear engineering is on safety of nuclear reactor. Passive cooling attracts most of researchers to use low melting point and high boiling point fluid. Molten salts exhibit low melting and high boiling points at normal atmospheric pressure condition. These qualities make molten salts useful in a variety of applications as a coolant or heat transfer fluid. In this study, Three-dimensional (3D) Computational Fluid Dynamics (CFD) simulations have been used to examine the hydraulic properties and heat transfer characteristics of molten salt NaNO3+KNO3 (60:40 wt ratio) in a horizontal pipe. Analytical data has been used to validate computed results. A comparative analysis has been conducted between the computational results and several correlations. This helps to understand the heat transfer characteristics. Using computational data, the local Nusselt number in the heater region is determined and compared to different correlations. The thermal-hydraulic properties of molten salt obtained from CFD results are compared with existing heat transfer correlations. The most appropriate correlations for obtaining the molten salt’s thermal-hydraulic properties have been discussed. Shah and London’s correlation to determine Nusselt number predicts very well in thermally developing region compared to Churchill and Oze’s correlation. CFD results are helpful to understand the hydraulic behavior of the fluid.
Assessment of deep-learning-based resolution recovery algorithm relative to imaging system resolution and feature size
Authors: Bukka Vaidyam Veerendra Rohit , Xu Moran , Andrew Matthew , Andreyev Andriy 
Published: February 2025

Abstract
High-resolution X-ray microscopy is crucial for non-destructive materials characterization, but achieving both high resolution and maintaining a wide field of view often necessitates time-consuming approaches. Deep learning super-resolution methods based on convolutional neural networks are bridging this gap to obtain high-resolution usable data for analysis from low-resolution images. This study evaluates a novel deep learning-based algorithm designed to overcome traditional limitations by learning a spatially varying point spread function from a set of registered low- and high-resolution image pairs. With a systematic methodology, we evaluated the algorithm’s superior performance in recovering features across a wide range of resolutions with increasing image quality degradation. It was also benchmarked against a classical iterative Richardson-Lucy deconvolution algorithm, and a well-known deep-learning-based super-resolution convolutional neural network SRCNN algorithm for the same images. Qualitative and quantitative evaluations using simulated foam phantoms showed that our algorithm shows excellent feature recovery, within 5 % of the ground truth, even for a large resolution ratio of 7:1 between the high- and low-resolution image pairs. Multiscale investigations on real data of porous material and a semiconductor device are also presented to highlight its feature recovery performance and versatility in real-world scenarios.
Oral History Metadata and AI: A Study from an LGBTQ+ Archival Context
Authors: Cocciolo Anthony 
Published: February 2025

Abstract
The purpose of this study is to explore the utility of generative AI technologies in creating oral history metadata. In particular, we will explore its ability to create descriptive metadata, specifically the Dublin Core description field, for oral histories that have existing transcripts. The oral history context this research is situated in is LGBTQ+ oral histories from three repositories in the United States. Research participants with knowledge of the area of library and archival science (N=14) will rate the AI-generated description created by ChatGPT 4 compared to the description created by hand, and describe qualitatively why one is better than the other. Results indicate that users prefer the AI-generated description 51.2 % of the time, compared to preferring the descriptive metadata created by a human 26.2 % of the time and being undecided about which is preferable 21.4 % of the time. Despite research that indicates that AI can reflect the bias of the datasets used to train it, we found that the AI created culturally-appropriate content 80.4 % of time compared with 75.6 % of the time when created by a human. The use of ChatGPT 4 is recommended as a tool to analyze interview transcripts to create descriptive metadata for oral histories documenting the LGBTQ+ community, although the content should be reviewed before being provided to users.
Utilization of steel slag in concrete: A review on durability and microstructure analysis
Authors: Qureshi Hisham Jahangir , Alghamdi Saeed Abdulkhaliq , Majdi Ali , Ahmad Jawad , Rahmawati Cut , Alattyih Wael , Alzlfawi Abdullah 
Published: February 2025

Abstract
This study addresses the research gap in understanding the durability aspects and microstructure properties of steel slag (SS) concrete. A series of different experimental results, including porosity, water absorption, pulse velocity, carbonation depth, chloride penetration, alkali–silica reaction, acid attacks, and shrinkage, were summarized to assess the durability of SS concrete. Similarly, the pozzolanic reaction of SS, the heat of hydration, scanning electronic microscopy, and thermogravimetry were used to assess the microstructure properties of SS-based concrete. Results indicate that the SS improved the durability aspects and microstructure properties of SS concrete. However, inconsistencies in slag quality, reactivity, and expansion risks due to free lime and magnesium oxide present challenges. Finally, the review also highlights the proposed recommendation for future research.
Amino acid Gemini surfactants: a review on their synthesis, properties and applications
Authors: Zhu Sen , Liu Baowen , Wang Bin , Liu Lijuan 
Published: February 2025

Abstract
The modern surfactant industry demands more efficient and environmentally friendly products as environmental regulations become more stringent. Amino acid Gemini surfactants (AAGSs), as the emerging green surfactants of amino acid surfactants, together with the Geminis, which consist of two or more amphiphilic moieties chemically linked by a spacer group, are the most reliable of these efficient green chemicals. With the diversity of structure and topological configuration of the spacer group, AAGSs have stronger aggregation ability and multifarious molecular configuration and aggregation morphology. They are used in various fields such as pharmaceuticals, biomedicine, daily chemicals, oil recovery and environmental treatment. This review contains detailed discussions on the synthesis of AAGSs from natural and non-natural sources using reactions such as Hofmann alkylation and Schotten-Baumann condensation. The physicochemical properties such as low CMC, good emulsification, different micelle forms, high biodegradability, antibacterial ability and biocompatibility are presented. Future research directions of AAGSs are also suggested, including their optimized synthesis, clarification of structure-performance relationships, and exploration of new applications in a wider range of fields.
Pengembangan Media Pembelajaran Video Animasi 2 Dimensi Berbasis Computing dan Slideshow Materi Cerita Rakyat Semarangan
Authors: Sholahunnisa Awalia , Insani Nur Hanifah 
Published: February 2025

The impact of globalization has reduced students' appreciation of local culture, including folklores. Students' knowledge of folklore that developed in Semarang is still minimal so teachers need to apply suitable learning methods and media. The solution to the problem is to develop learning media in the form of animated videos of Semarangan folklore material. This research uses the method of Research and Development or development research. The data from this study were obtained from the needs analysis, namely teachers and students of SMP Negeri 12 Semarang using an instrument in the form of a questionnaire, and the results of validation tests from material experts and , media experts. The result of this research is that students and teachers need learning media in the form of animated audiovisual media. The prototype of animated media was designed based on the needs analysis of students and teachers. The selection of fonts, colors is adjusted to the interests of teachers and students, namely the selection of fonts, and a combination of bright colors. Based on the validation test results from material and media experts, the media that has been designed is included in the category that is very feasible as a learning media.