bluuebunny/crossref_metadata_2025_split huggingface dataset:
Quality of Life After Lower Leg Reconstruction With the Latissimus Dorsi Free Flap in Pediatric Patients
Authors: Bustamante Atenas , Zavala Abraham , Iglesias Martin , Tornero Ray , Machaca Lucero , De Pawlikowski Wieslawa 
Published: March 2024

Background
The latissimus dorsi free flap is a widely used reconstructive technique for complex lower leg defects in the pediatric population due to its reliability and anatomical features. However, the impact of this technique on the postoperative quality of life in children and adolescents, who require appropriate lower extremity function during their developmental period, remains to be analyzed.

Methods
Patients who underwent microsurgical lower leg reconstruction using the latissimus dorsi flap were analyzed retrospectively. The quality of life of these patients was assessed prospectively using the Lower Extremity Functional Scale (LEFS) at a minimum of 18 months after surgical reconstruction.

Results
Sixteen pediatric patients who had severe lower extremity injuries and underwent latissimus dorsi free flap reconstruction met the inclusion criteria. The mean follow-up period was 33.9 months (22–64 months). Two patients experienced postoperative complications: one had partial flap necrosis and surgical site infection, while the other developed a surgical site infection. The LEFS scores ranged from 26 to 80, with a mean score of 64.6. Remarkably, 14 of 16 patients achieved LEFS scores consistent with at least the 10th percentile when compared with normative data. Patients with severe associated fractures presented with the lowest scores.

Conclusions
Based on our findings, the latissimus dorsi flap is reaffirmed to be an excellent choice for lower leg reconstruction in the pediatric population. It effectively restores the quality of life in patients who have experienced moderate to severe lower extremity injuries.
Industry Sponsorship Bias in Collagenase Clinical Trials for Dupuytren Disease
Authors: Gray Kelsey M. , Khatiwada Priyenka , Capito Anthony E. 
Published: March 2024

Background
Collagenase clostridium histolyticum (collagenase) was introduced in 2010 creating a nonoperative treatment option for Dupuytren disease with promising results in sponsored clinical trials. A meta-analysis was performed to investigate industry sponsorship bias.

Methods
A systematic review of collagenase treatment of Dupuytren contracture was conducted. Articles containing mesh terms including “microbial collagenase” and “Dupuytren's contracture” were searched and limited to only clinical trials with similar protocols for inclusion. Meta-analysis of treatment endpoints of correction of contracture to 0–5 degrees after first and last injection was conducted comparing sponsored versus nonsponsored studies.

Results
Sixteen of the 29 identified articles met criteria for inclusion. Nonsponsored studies reported a significantly higher rate of meeting the primary treatment endpoint compared to sponsored studies after single injection for all joints (69.6% vs 56% P < 0.01), metacarpophalangeal joint (96% vs 64% P < 0.01), and proximal interphalangeal joint (67% vs 36% P = 0.011). The correction in contracture rates was similar between groups with studies evaluating more than one injection.

Conclusions
Nonsponsored studies published higher success rates in meeting the primary endpoint of full correction after single injection than sponsored studies; however, similar results with multiple injections. This study demonstrated that sponsored studies of collagenase produced highly powered studies that may be reliably depended on for evidence-based clinical application.
Combined Targeted Muscle Reinnervation With Regenerative Peripheral Nerve Interfaces Decreases Long-Term Narcotic Use in Amputees
Authors: Wee Corinne , Boas Samuel , Coquillard Cristin , Cai Yida , Kurlander David , Maasarani Samantha , Leavitt Tripp , Long Tobias , Lineberry Kyle , Khouri Joseph 
Published: March 2024

Purpose
Combined targeted muscle reinnervation with regenerative peripheral nerve interfaces (“TMRpni”) is a recently described nerve management strategy that leverages beneficial elements of targeted muscle reinnervation (TMR) and regenerative peripheral nerve interface (RPNI) techniques. This study aimed to evaluate the effect of TMRpni on long-term opioid consumption after amputation. We hypothesize that TMRpni decreases chronic opioid consumption in amputees.

Methods
This is a retrospective cohort study of all patients who underwent TMRpni between 2019 and 2021. These patients were age-matched at a 1:1 ratio with a control group of patients who underwent amputation without TMRpni. Statistical analysis was performed using SPSS Version 28.0.

Results
Thirty-one age-matched pairs of patients in the TMRpni and control groups were included. At 30 days after surgery, there was no significant difference in number of patients who required an additional refill of their opioid prescriptions (45% vs 55%, P = 0.45) or patients who continued to actively use opioids (36% vs 42%, P = 0.60). However, at 90 days after surgery, there was a significantly lower number of patients from the TMRpni group who reported continued opioid use compared with the control group (10% vs 32%, P = 0.03).

Conclusions
This study demonstrates that TMRpni may translate to decreased rates of chronic opiate use. Continued study is indicated to optimize TMRpni techniques and patient selection and to determine its long-term efficacy.
Infrared astronomy beyond JWST: the Moon perspective
Authors: Maillard Jean-Pierre 
Published: March 2024

In the first special issue on ‘Astronomy from the Moon: the next decades', two projects for the infrared domain, considered as justifying a lunar implementation, were presented: a general purpose light collector for the 1–200 μm range, of diameter much larger than any ELT on Earth and a specialized instrument in the very far-infrared aiming at the detection of the weak CMB spectral distortions. Learning from the launch of JWST, to surpass it in spatial, spectral resolution, spectral coverage and sensitivity, the concept of a large infrared, lunar collector is revisited to be specified on a more realistic approach. The telescope is designed to fit in its stowed configuration into the fairing of a future cargo launcher, in order to be deployed on the Moon in robotic mode from a single launch. With these constraints, its diameter is limited to 13 m, i.e. just twice JWST. The choice of the potential sites is also better defined, by selecting the coldest lunar spots that could provide a passive cooling, on average colder than is obtained for JWST at L2. In conclusion, the advantages and the requirements for the development of such a facility on the Moon in the next decades are reviewed.
This article is part of a discussion meeting issue ‘Astronomy from the Moon: the next decades (part 2)’.
A collective inquiry into betweenness: emerging scholars of color navigating the socialization process
Authors: Lim Ahreum , Jung Daeun , Lee Eunsun 
Published: March 2024

PurposeAs emerging scholars of color with transnational backgrounds, we collectively recount our socialization experiences in US higher education institutes. We explore moments of betweenness as catalysts for envisioning a more inclusive academia that operates beyond the tokenism of diversity.Design/methodology/approachEmploying betweener autoethnography (Diversi and Moreira, 2018), we inquire into the sense of impasse encountered by South Korean female emerging scholars in the field of education in becoming an outsider within the academic system.FindingsChronicling our shifts in perspectives of our positionality, we interweave inquiries motivating us to challenge normative pressures and map our betweener experiences onto the Wiedman and DeAngelo’s (2020) socialization model. Through this process, we wedge open in-between spaces in the socialization process that accommodate the nuanced positionality of transnational scholars.Originality/valueIntegrating postcolonial critiques on the Western-centric meritocratic academia, this piece sheds light on the complexity and fluidity of emerging transnational scholars’ socialization processes. The thick, nuanced description deepens the understanding of the complexity of their identity negotiation within the dominant logics of academia. Our inquiries interwoven through betweener autoethnography serve as guidance for mentoring international graduate students and transnational scholars.
The effects of world heritage status on European city residents’ subjective quality of life
Authors: Alfaro-Navarro José Luis , Andrés-Martínez María Encarnación 
Published: March 2024

PurposeBeing awarded world heritage status is a distinguishing factor when it comes to promoting tourism in a city. Tourism in these cities should be developed in a way that does not compromise either the city’s heritage or the inhabitants' quality of life. Thus, the main purpose of this paper is to analyze the effects of a European city achieving world heritage status on the subjective quality of life of its citizens.Design/methodology/approachFirst of all, we classify European cities according to whether or not they have been declared world heritage sites. Then, we analyze the effect of this classification on the main aspects used to measure the residents' perception of quality of life that are available in the Flash Eurobarometer 419.FindingsThe results show that achieving world heritage status has a negative effect on residents' perceptions of the noise level, air quality and feeling of safety. However, it does not affect their perceptions of public transport or cleanliness. In addition, world heritage status positively affects residents’ perceptions of the cultural activities in the city and their ease of finding a job. Residents report high levels of happiness in both world heritage and non-heritage cities, although levels are somewhat higher in non-heritage cities.Originality/valueResidents' perceptions of the influence of tourism on their quality of life are undoubtedly of major importance; however, due to a lack of available data, few studies have examined this subjective quality of life at the city level.
“Inclusion is definitely a possibility for all”: Promoting inclusive education through a critical professional development schools model
Authors: Sebti Latifa , Elder Brent C. 
Published: March 2024

PurposeIn this article, we highlight ways in which disability critical race theory (DisCrit) (Annamma et al., 2013), inclusive education and community-based participatory research (CBPR) can be used within professional development schools (PDS) to provide students with disabilities with more access to inclusive classrooms. At a grade 4–6 elementary school, we developed a model of a critical PDS to promote inclusive education and facilitate the transition of students of color with disabilities from self-contained to inclusive classrooms. We conducted semi-structured interviews and used action plan meetings with school administrators, teachers, professionals and students with disabilities and their parents to assess the impact of our critical PDS model. Findings suggest this model had a positive impact on administrators’ and teachers’ critical consciousness, ideological and instructional practices, students of color with disabilities’ social, academic and personal outcomes, as well as a schoolwide culture of inclusion and social justice. This study can inform tailored professional development efforts to improve educators’ inclusive practices.Design/methodology/approachWe conducted semi-structured interviews and used action plan meetings with school administrators, teachers, professionals and students with disabilities and their parents to assess the impact of our critical PDS model.FindingsThe findings of this study suggest this model had a positive impact on administrators’ and teachers’ critical consciousness, ideological and instructional practices, students of color with disabilities’ social, academic and personal outcomes, as well as a schoolwide culture of inclusion and social justice.Practical implicationsThis study can inform tailored professional development efforts aiming to improve educators’ inclusive practices.Originality/valueWe developed a model of a critical PDS to promote inclusive education and facilitate the transition of students of color with disabilities from self-contained to inclusive classrooms.
Who Did What to Whom and How: A Scoping Review of Interventions to Promote Children's Self‐Efficacy in Mainland China
Authors: Wang Miao , Liu Kexin , Zhou Yue , Huang Xiaoyan 
Published: March 2024

ABSTRACTSelf‐efficacy refers to an individual's judgement, belief and perception of their capability to accomplish specific tasks, which is crucial for children's mental well‐being. The primary objective of this scoping review was to systematically examine intervention studies aimed at enhancing children's self‐efficacy in Mainland China, intending to inform social work practices in child services. We conducted a comprehensive search of articles in Web of Science and CNKI to review empirical intervention studies published before March 2022 in either Chinese or English. The selection criteria included all empirical intervention studies focused on improving self‐efficacy in children in Mainland China. A total of 17 studies were identified and included in the review. Among these, six studies focused on general self‐efficacy, while the remaining 11 examined domain‐specific self‐efficacy. Seven studies provided compensatory interventions to children facing adversity, five studies implemented preventive services, and another five offered developmental services to children in regular circumstances. Fourteen programmes exclusively served children, while three studies involved parents. Notably, most of the included interventions were facilitated by research teams from universities, with only one led by a social work department. Education modalities and comprehensive interventions were commonly used and found to be effective. The current state of intervention studies underscores the need for programmes that utilize effective strategies and approaches to enhance children's self‐efficacy. Social workers are encouraged to play both direct and indirect roles in services aimed at improving children's self‐efficacy.
Pathogen Avoidance and Outgroup Avoidance During the First Wave of the COVID‐19 Pandemic
Authors: Kang Youngjin 
Published: March 2024

AbstractBehavioral immune system (BIS) theory explains that humans possess an adaptive psychological mechanism that helps them stay away from potential sources of pathogens. The theory claims that potential sources of pathogens also include outgroups, such as racial and ethnic minorities, because outgroup members potentially carry infectious diseases to which ingroup members have not developed immunity. In order to examine this controversial claim, the current study investigated how outgroup avoidance was associated with other types of pathogen avoidance during the COVID‐19 pandemic. During the first wave of the COVID‐19 pandemic, participants from the United States (N = 386) responded to questions pertaining to pathogen threat, pathogen avoidance, and outgroup avoidance. The data were statistically analyzed to identify significant associations between those variables. The results indicated that outgroup avoidance was positively associated with avoidance of personal pathogen cues (i.e., social distancing) but no other types of pathogen cues (i.e., wearing a mask and washing hands). This result aligns with the recent theoretical argument that the outgroup avoidance activated by the BIS (e.g., xenophobia) is a byproduct of avoiding infected ingroup rather than outgroup individuals.
Reviewer Acknowledgements for International Journal of Contemporary Education, Vol. 7, No. 1
Authors: Oscar William 
Published: March 2024

International Journal of Contemporary Education (IJCE) would like to acknowledge the following reviewers for their assistance with peer review of manuscripts for this issue. Many authors, regardless of whether IJCE publishes their work, appreciate the helpful feedback provided by the reviewers. Their comments and suggestions were of great help to the authors in improving the quality of their papers. Each of the reviewers listed below returned at least one review for this issue.Reviewers for Volume 7, Number 1 Aurora Q. Pestano, University of San Jose Recoletos, PhilippinesBožić-Lenard Dragana, University of Osijek Croatia, CroatiaClaire Goode, Otago Polytechnic at Te Pūkenga, New ZealandDina Radeljas, Mohawk Valley Community College, USAEdward Bolden, Case Western Reserve University, USAFederica Cornali, University of Turin, ItalyGiuseppe Maugeri, University of Urbino, ItalyInaad M Sayer, University of Human Development, IraqIvan Lenard, Elementary School Ladimirevci, CroatiaMatthew Schatt, University of Florida, USAVassiliki Pliogou, University of Western Macedonia, Greece William OscarEditorial AssistantInternational Journal of Contemporary Education------------------------------------------------------------Redfame Publishing9450 SW Gemini Dr. #99416Beaverton, OR 97008, USATel: 1-503-828-0536 ext. 509Fax: 1-503-828-0537E-mail 1: ijce@redfame.comE-mail 2: ijce@redfame.orgURL: http://ijce.redfame.com
Bistable Aerial Transformer: A Quadrotor Fixed-Wing Hybrid That Morphs Dynamically Via Passive Soft Mechanism
Authors: Weakly Jessica , Li Xuan , Agarwal Tejas , Li Minchen , Folk Spencer , Jiang Chenfanfu , Sung Cynthia 
Published: March 2024

Abstract
Aerial vehicle missions require navigating trade-offs during design, such as the range, speed, maneuverability, and size. Multi-modal aerial vehicles enable this trade-off to be negotiated during flight. This paper presents a Bistable Aerial Transformer (BAT) robot, a novel morphing hybrid aerial vehicle that switches between quadrotor and fixed-wing modes via rapid acceleration and without any additional actuation beyond those required for normal flight. The design features a compliant bistable mechanism made of thermoplastic polyurethane (TPU) that bears a large mass at the center of the robot’s body. When accelerating, inertial forces transition the vehicle between its stable modes, and a four-bar linkage connected to the bistable mechanism folds the vehicle’s wings in and out. The paper includes the full robot design and a comparison of the fabricated system to the elastodynamic simulation. Successful transitions between the two modes in mid-flight, as well as sustained flight in each mode indicate that the vehicle experiences higher agility in the quadrotor mode and higher flight efficiency in the fixed-wing mode, at an energy equivalent cost of only 2 s of flight time per pair of transitions. The vehicle demonstrates how compliant and bistable mechanisms can be integrated into future aerial vehicles for controllable self-reconfiguration for tasks such as surveillance and sampling that require a combination of maneuverability and long-distance flight.
Role of amino acid 159 in carbapenem and temocillin hydrolysis of OXA-933, a novel OXA-48 variant
Authors: Rima Mariam , Oueslati Saoussen , Cotelon Garance , Creton Elodie , Bonnin Rémy A. , Dortet Laurent , Iorga Bogdan I. , Naas Thierry 
Published: March 2024

ABSTRACT

OXA-48 has rapidly disseminated worldwide and become one of the most common carbapenemases in many countries with more than 45 variants reported with, in some cases, significant differences in their hydrolysis profiles. The R214 residue, located in the ß5-ß6 loop, is crucial for the carbapenemase activity, as it stabilizes carbapenems in the active site and maintains the shape of the active site through interactions with D159. In this study, we have characterized a novel variant of OXA-48, OXA-933 with a single D159N change. To evaluate the importance of this residue, point mutations were generated (D159A, D159G, D159K, and D159W), kinetic parameters of OXA-933, OXA-48 D159G, and OXA-48 D159K were determined and compared to those of OXA-48 and OXA-244. The
bla
OXA-933
gene was borne on Tn
2208
, a 2,696-bp composite transposon made of two IS
1
elements surrounded by 9 bp target site duplications and inserted into a non-self-transmissible plasmid pOXA-933 of 7,872 bp in size. Minimal inhibitory concentration values of
E. coli
expressing the
bla
OXA-933
gene or of its point mutant derivatives were lower for carbapenems (except for D159G) as compared to those expressing the
bla
OXA-48
gene. Steady-state kinetic parameters revealed lower catalytic efficiencies for expanded spectrum cephalosporins and carbapenems. A detailed structural analysis confirmed the crucial role of D159 in shaping the active site of OXA-48 enzymes by interacting with R214. Our work further illustrates the remarkable propensity of OXA-48-like carbapenemases to evolve through mutations at positions outside the β5-β6 loop, but interacting with key residues of it.
Teichmüller’s Modulsatz and the Variation of the Dirichlet Integral
Authors: Dubinin V. N. 
Published: March 2024

AbstractWe show that
changing the level curve of a harmonic function
with the classical Hadamard variation with a small parameter
entails a change in the Dirichlet integral of the function
which is quadratic in the parameter.
As a corollary,
we supplement the well-known theorem of Teichmüller
about the sum of moduli of doubly connected domains
into which an annulus is subdivided
by a continuum that differs little from a concentric circle.
Metabolomics as a Candidate for Endometriosis Biomarker: A Systematic Review
Authors: Meidyana Shafira , Fedora Katherine 
Published: March 2024

Background: To date, diagnosis is still a challenge in managing endometriosis. There is a need to develop a less invasive yet accurate approach, such as a biomarker, to help diagnose endometriosis earlier and more precisely. Metabolomics, the study of metabolites, are thought to provide a more accurate relation to phenotype compared to other omics technology and may help develop endometriosis biomarkers. This review aims to systematically summarize evidence regarding the use of metabolomics studies in the diagnosis of endometriosis. Methods: This review was conducted according to PRISMA 2020 guidelines. Including studies on endometriosis and metabolomics in Medline, Embase, and Cochrane Library to May 2022. Inclusion: Women of reproductive age, laparoscopically diagnosed — exclusion criteria: no full-text, languages other than English, and animal studies. Papers were screened and extracted using Covidence, appraised using Newcastle-Ottawa Scale (NOS), by two independent reviewers. Results: A total of 33 studies are included in this review, and 24 showed positive results regarding the metabolites identified and their association with endometriosis. Twenty-four studies reported good area under curve (AUC), sensitivity, and specificity scores in diagnosing endometriosis using a prediction model from the attained metabolites. However, the summary of these scores is not feasible due to the lack of standardization in reporting metabolomics studies. Both serum and endometriotic lesion microenvironments, such as peritoneal fluid, endometrioma, follicular fluid, and tissue lesions, give essential information on which metabolites are altered in endometriosis. Phosphatidylcholine (PC), acylcarnitines (AC), and sphingomyelins (SM) are these studies’ most frequent significant metabolites, but their levels vary. Although all studies had an overall good appraisal score, regarding confounders included, the variation in their methods of analysis and prediction model approach should be interpreted with caution. These predictions are also mostly done without using two different data groups for test and validation. Conclusions: Metabolomics studies may become an alternative for a less invasive approach to diagnosing endometriosis. This review revealed how encouraging results from metabolomics studies are. However, the need for more standardization in the study report and preliminary design for making a prediction model is still in the way of fully trusting metabolomics studies to account for endometriosis diagnostic biomarkers. Registration: PROSPERO CRD42022334916