bluuebunny/crossref_metadata_2025_split huggingface dataset:
Exercise benefits and barriers perceived by hemodialysis patients: relationship with fatigue and physical activity level
Authors: Aktaş Arslan Fatma Cansu , Düger Tülin 
Published: March 2024

Aims: The aim of our study was to determine the attitudes of hemodialysis (HD) patients towards exercise and to determine the relationship between physical activity level (PAL) and fatigue.
Methods: This cross-sectional study was conducted with 113 HD patients (57.8±5.96) aged 18-65 years. Personal information form, fatigue impact scale (FIS), international physical activity questionnaire short form (IPAQ-SF), and dialysis patient-perceived exercise benefits and barriers scale (DPEBBS) were used as data collection tools.
Results: The mean DPEBBS total score was 64.35±6.15 and PAL was low. The most commonly perceived exercise benefits were preventing muscle atrophy and maintaining a stable body weight, while the most common exercise barriers (EB) were not understanding how to exercise and fatigue. There was a weak negative correlation between the PAL of the patients with the Perceived Exercise Barriers subscale (r=-0.275, p=0.003) and a weak positive correlation between the total scale score (r=0.318, p=0.001). There was a weakly significant positive correlation between the Cognitive, Physical, Psychosocial sub-dimension of Fatigue and Total FIS with the Perceived Exercise Barriers sub-dimension (r=0.337, p=0.000; r=0.358, p=0.000; r=0.334, p=0.000; r=0.387, p=0.000). A very weakly significant negative correlation was found between the Fatigue Cognitive, Physical, Psychosocial sub-dimension and Fatigue Total Impact Dimension with the total scale score (r=-0.247, p=0.008; r=-0.234, p=0.013), r=-0.222, p=0.018, r=-0.243, p=0.003) .
Conclusion: HD patients had higher perceptions of the benefits of exercise. It was concluded that the perception of EB decreased as PAL increased and the perception of EB increased as fatigue levels increased. It is recommended that specialized physiotherapists evaluate HD groups at risk in detail and create individual interventions that support HD patients' compliance with exercise.
Frequency of seronegative cases in autoimmune hepatitis and their association with the systemic immune inflammation index
Authors: Mutlu Bilgiç Nermin 
Published: March 2024

Aims: It is suggested that a deficiency in B cells plays a role in pathogenesis of seronegative autoimmune hepatitis (snAIH). The lack of B cells leads to notable changes in the variety of leukocyte types within the bloodstream. This study aimed to determine the frequency of snAIH in patients with autoimmune hepatitis, as well as to explore the relationship between snAIH and leukocyte-based inflammatory indices.
Methods: In this retrospective study, 57 patients newly diagnosed with autoimmune hepatitis were included. According to clinical and pathological findings, patients were classified into seropositive autoimmune hepatitis (spAIH) and snAIH groups. The inflammation indices included the platelet to lymphocyte ratio (PLR), the neutrophil to lymphocyte ratio (NLR), and the systemic immune-inflammation index (SII).
Results: The frequency of snAIH was 26.3%. The snAIH group exhibited higher NLR (3.0 vs. 1.5, p
EVALUASI POSTUR DAN MANUAL HANDLING PEKERJA DI UNIT PANDAI BESI RONI MENGGUNAKAN METODE WORKPLACE ERGONOMIC RISK ASSESMENT (WERA) DAN OVAKO WORK POSTURE ANALYSIS SYSTEM (OWAS)
Authors: Farmizan Kemal Farmizan , Nofirza Nofirza , Hamdy Muhammad Ihsan , Melfa Yola  , Misra Hartati  
Published: March 2024

Unit Pandai Besi Roni merupakan sebuah perusahaan yang bergerak di bidang produksi alat alat perkakas dari besi atau yang lainnya, yang beralamatkan di Simpang Manga, Kec. Kelayang, Kab. Indragiri Hulu. Aktivitas yang diamati sebanyak 3 aktivitas dari 3 stasiun kerja. Kegiatan produksi masih menggunakan metode tradisional dan terdapat banyak aktivitas material secara manual, sehingga pastinya banyak sekali postur kerja yang tidak ergonomis. Tujuan penelitian dilakukan adalah untuk mengevaluasi postur kerja dan manual handling menggunakan metode Workplace Ergonomic Risk Assesment (WERA) dan Ovako Work Posture Analysis System (OWAS). Berdasarkan hasil penelitian dengan metode WERA, stasiun pembakaran dikategorikan level resiko medium mendekati low, stasiun pembentukan dan finishing dikategorikan level resiko medium mendekati high. Maka dari itu diperlukan metode OWAS agar mempermudah dalam melakukan penelitian lebih lanjut. Sedangkan hasil penelitian dengan metode OWAS, stasiun kerja dengan level risiko medium pada stasiun finishing, stasiun kerja dengan level risiko tinggi pada stasiun pembentukan. Usulan perbaikan yang diberikan adalah me-redesign ukuran meja pada stasiun pembentukan.
Effectiveness of Cellulose Acetate Nanofiber from Banana Leaf Waste (Musa paradisiaca L.) as an Antibacterial Filter in Masks
Authors: Sinaga Muhammad Zulham efendi , Simanungkalit Sylvia Romalia , Sembiring Brian Cristoper , Sahputra Dzul Hadi , Sihotang Putri Amelia , Al-Khairi Shofi Tasa 
Published: March 2024

The COVID-19 pandemic requires all people in Indonesia to comply with health protocols, from washing hands to wearing masks. Cloth masks are one of the masks that are widely used by the community. However, the public needs to pay attention to the rules of the cloth masks used. The purposes of this study were to produce an antibacterial filter on masks and to find out the effective and efficient processing of banana stems as an antibacterial filter on masks. Banana stems were chosen as the raw material because it is easy to obtain, has a cellulose content of ± 63%, and has antibacterial compounds in it. The stages of this research were sample preparation, phytochemical screening of banana stems, isolation of α-cellulose and synthesis of cellulose acetate from α-cellulose which were further characterized by using FTIR, manufacture of dop solution, manufacture of nanofiber membranes by electrospinning, and product application. The resulting product was then tested by pressure drop test, contact angle test, antibacterial activity test, SEM test, and porosity test. The test results showed that the resulting product was a nanofiber with a fiber diameter of ± 220.74075 nm, had antibacterial activity which was indicated by the formation of inhibition zone with a diameter of ± 14.8 mm in Escherichia coli and ± 9.8 mm in Staphylococcus. aureus, the filter is hydrophilic with an average contact angle of 60°. From the observations, it can be concluded that banana stems have the potential as an antibacterial filter on masks.
Application of computer on Pharmacogenomics
Authors: Amanat Muhammed , Singh Randhir 
Published: March 2024

Background Pharmacogenomics is an emerging field that explores the relationship between a person’s genetic makeup and their response to drugs.
Objectives: Computer applications have been instrumental in advancing pharmacogenomics research and facilitating personalized medicine. In this abstract, we review some of the key computer applications used in pharmacogenomics research, including bioinformatics tools for analyzing genetic data, machine learning algorithms for predicting drug response, and clinical decision support systems for guiding drug selection and dosing. We also highlight the challenges and opportunities in the field of pharmacogenomics, including the need for large-scale, multi-omics datasets, and the importance of developing robust and interpretable machine learning models. Overall, computer applications have played a critical role in enabling pharmacogenomics research and have the potential to revolutionize the practice of medicine by facilitating the development of more personalized and effective drug therapies.
Bangladesh Journal of Medical Science Vol. 23 No. 02 April’24 Page : 300-308
Assessment of attentional disorders in school-aged children with visual impairment in the province of Kenitra
Authors: Dahou Badreddine , Touhami Ahami Ahmed Omar , Ziri Rabea 
Published: March 2024

Background Attention deficit disorder refers to a neurodevelopmental disorder that has attracted great interest in recent decades with a prevalence of about 5% of children according to the DSM V. The vision constitutes “the modality of knowledge” since this meaning, primitive, offers perceptual experiences at the origin of the development of the first cognitive acquisitions. However, the repercussions of a disorder affecting vision are significant as to the. It is therefore important to distinguish it from an intellectual development disorder.
Aims and Methods This study is intended to be descriptive and analytical. It aims to highlight the attention deficit in visually impaired children enrolled in the first year of primary school. Based on 6732 children, 1761 have a vision of less than 7/10, and only 85% of them benefit from automatic refraction at the optical unit, or 1497 children. Three devices were thus used: the test of entangled figures, the observation grid and the test of the two Zazzo dams. These devices make it possible to detect deficits in the attention and concentration of visually impaired students in school in relation to the decline in their level of visual acuity. The latter leads to attentional disorders resulting in concentration defects and distractibility. This decrease in attention occurs in proportion to that of visual acuity in visually impaired children.
Results & Conclusion One of the major interests in assessing attention deficit in children with visual impairments is the development of a compulsory childcare programfor pre-school child and an educational awareness plan for parents.
Bangladesh Journal of Medical Science Vol. 23 No. 02 April’24 Page : 491-497
Patient with a rare weaker subgroup-A exhibiting ABO discrepancy: a case report
Authors: Yousuf Rabeya , Yusof Nurasyikin , Suhemi Nur Afifah , Abdullah Thalith Nor Fadzliana , Aziz Suria Abdul 
Published: March 2024

Weaker subgroups have the potential to cause problems in the immunohaematological testing in the blood banks. We report here a case of rare weaker subgroup A, detected during the usual ABO grouping. A 49-year-old lady exhibited a discrepancy in the forward and reverse groupings. In forward-grouping, there was a mixedfield reaction with anti-A and anti-A,B while there was no reaction with anti-B. The reverse grouping showed no reaction with the A1 and A2 cells, but the reaction with B-cell was 4+. Further tests were performed and revealed a weaker subgroup of A. It is crucial to properly investigate and resolve any discrepancy in ABO grouping before commencing transfusion to avoid any wrong blood transfusion. This case report may assist others in resolving the ABO blood group discrepancies.
Bangladesh Journal of Medical Science Vol. 23 No. 02 April’24 Page : 546-550
«Зелена» енергетика в концепції циркулярної економіки: відновлення та використання поновлюваних джерел у нестабільних умовах
Authors: Прохорова Вікторія , Ус Віталій 
Published: March 2024

У статті проаналізовано важливість «зеленої» енергетики в рамках концепції циркулярної економіки, зокрема, в умовах нестабільності. Актуальність зазначеної проблематики полягає в тому, що використання відновлюваних джерел енергії та відновлення ресурсів сприяє створенню сталої та ефективної енергетичної системи.
Метою статті аналіз важливості «зеленої» енергетики в концепції циркулярної економіки та використання поновлюваних джерел у нестабільних умовах. Відновлювані джерела енергії, такі як сонячна, вітрова, геотермальна, хвильова, гідроенергетика, біомаса, сприяють створенню енергетичної системи, яка базується на необмежених природних ресурсах, що дасть змогу зменшити залежність від нестабільних і надто дорогих викопних джерел енергії, таких як вугілля та нафта, і забезпечити стале, дешеве та надійне енергопостачання.
У статті розглянуто концепцію циркулярної економіки та визначено її мету, яка полягає у максимальному використанні відновлювальних джерел енергії, мінімізації викидів шкідливих речовин під час виробництва та споживання енергії та зменшенні потреби в постійному видобутку обмежених ресурсів. Розглянуто, також, зарубіжний досвід впровадження принципу 3-R.
Представлено аргументи щодо взаємозв’язку між «зеленою» енергетикою і циркулярною економікою, що сприяє формуванню «зеленої» економіки. Запровадження «зеленої» економіки є важливим кроком до сталого розвитку суспільства та захисту навколишнього середовища. Реалізація «зеленої» економіки включає такі заходи, як сприяння використанню відновлюваних джерел енергії, впровадження енергозберігаючих та енергоефективних технологій, стимулювання виробництва продуктів з урахуванням можливості переробки. «Зелена» економіка сприяє підвищенню якості життя людства, створює нові робочі місця у секторі відновлюваних технологій та сприяє підвищенню конкурентоспроможності всієї економіки.
The Impact of COVID-19 Pandemic on Ocular Oncology Services at Cipto Mangunkusumo Hospital, Indonesia
Authors: Anggraini Neni , Nursanti Hanifah Rahmani , Mahyuddin Mutmainah 
Published: March 2024

Background:: Delay of diagnosis and treatment in ocular oncology services due to the COVID-19 pandemic is very disadvantageous. This study aimed to evaluate the impact of COVID-19 on new patients with suspected eye tumors in terms of volume, characteristics, and waiting time for a procedure. Methods: : A retrospective study based on hospital records of new patients was held in the ocular oncology clinic of Cipto Mangunkusumo Hospital, a tertiary eye care center in Jakarta, Indonesia. Patients were analyzed descriptively based on three time periods: pre-COVID-19, COVID-19 social restriction, and post-COVID-19 social restriction. Each patient was stratified according to case priority during the COVID-19 pandemic suggested by Indonesia’s Ophthalmologist Association (IOA). Results: During the COVID-19 social restriction between March to June 2020, new patient volume decreased by 73.1%, with a 75.5% decline in referrals from the governmental hospital. Elderly, pediatric, and highly educated patients were less likely to visit the clinic. Patients with acute onset, invasive or metastatic tumors, and advanced T-stage were more likely to be referred to the hospital. Third-priority cases referred with a lower ratio during COVID-19 social restriction (29% vs 44.9% in pre-COVID-19 and 35.1% in post-COVID-19 social restriction) and had to wait longer for the procedure (41 (18–60) days vs 28.5 (11–63) days in pre-COVID-19 and 16.5 (7–67) days in post-COVID-19 social restriction). Conclusions: : As the healthcare service was overwhelmed by COVID-19 patients, referral to ocular oncology services was severely disrupted, particularly in elderly, pediatric, and early T-stage patients. Strategies are needed to ensure that highly prioritized cases may access the services.
Activity of Matrix Metalloproteinase-7 (MMP-7) Related to Heparin-Binding Epidermal Growth Factor (HB-EGF) Activation in Squamous Cell as Diagnostic Biomarker for Early Detection And Treatment of Maxilarian Cancer: Review Article
Authors: Thongiratama Gregorius William , Dhananjaya Gede Arya Diva , Mulya Happy Kusuma , Ruma I Made Winarsa 
Published: March 2024

Background: Squamous cell carcinoma (SCC) has a higher chance of occurance and progression in maxillary sinus cancer than other paranasal sinus cancers (80%). Matrix metalloproteinase-7 (MMP-7) is a protease specified in collagen type IV degradation and Heparin Binding Epidermal Growth Factor activation, which causes an increase in squamous cell carcinoma proliferation and metastasis Methods: This review aims to identify the potential role of MMP-7 as a target for prevention and therapeutic modality to manage SCC sinus maxillary cancer. We did literature searching in several databases to elucidate the importance of the MMP-7 pathway in SCC sinus maxillary cancer progression. Results: : Increasing expression and activity of MMP-7 are associated with maxillary sinus cancer progression. Squamous cells, the most impacted in maxillary sinus cancer, sustain dysplasia due to heparin-binding epidermal growth factor (HB-EGF) activation into EGF by MMP-7 and Cluster of Differentiation 44 (CD44) binding complexes that trigger high proliferation and mitogenic activity. The therapeutic function of MMP-7 occurs by affecting the protein 53 (p53) in cancer cell apoptosis initiation by specific interaction with CD44. Conclusion: MMP-7 could be an alternative therapeutic target and potential treatment option for maxillary sinus cancer. Furthermore, more trials should be done to test the relevancy of MMP-7 uses as an SCC sinus maxillary cancer modality
Early Recurrence Adenoid Cystic Carcinoma of Paranasal Sinus, A Case Report
Authors: Marzaini, MD Nikrial Dewin , Yossarsongko Handoko Nugroho , Rayhani Farilaila , Soeis Dewi Syafriyetti 
Published: March 2024

Introduction: Adenoid cystic carcinoma (ACC) of the head and neck is a rare salivary gland tumor. It grows and spreads in silence until causing a symptom. Surgery is still the main treatment of choice although complete resection is hard to achieve most of the time. Case Presentation: This report presents an adult female with ACC of the left hard palate and left maxillary sinus, this patient also had slight lymph nodes enlargement. She underwent sub-total maxillectomy followed by locoregional radiotherapy. The tumor spreads out to vertebral bones within one year and keeps on progressing despite bone radiation. It recurred locally and appeared in the neck lymph node 2 months after bone metastasis. Lung metastasis happened 3 months later and soon she passed away. Mortality happened in less than two years after initial treatment. Conclusion: : High tumor grade, advanced T stage, lymph node involvement, perineural invasion, and paranasal sinus location clearly define poor prognostic factors. In this case, adjuvant radiotherapy for poor prognostic factors ACC doesn’t give any benefit in locoregional control or overall survival.
Presacral Schwannoma Resembling Lymph Node Metastasis in a Patient with Locally Advanced Prostate Cancer
Authors: Hama Yukihiro , Tate Etsuko 
Published: March 2024

Introduction: SSchwannomas originating in the pelvic region are rare and present diagnostic challenges when they coexist with malignancies. Case Presentation: A 58-year-old man with urinary frequency and an elevated prostate-specific antigen level underwent preoperative imaging. T2-weighted magnetic resonance imaging (MRI) of the prostate identified an irregular hypointense lesion with extracapsular invasion, as well as a presacral nodule resembling lymph node metastasis. The presacral nodule exhibited an intermediate signal intensity on the apparent diffusion coefficient map that was derived from diffusion-weighted images. Dynamic contrast-enhanced MRI revealed persistent enhancement in the presacral node, while the prostate tumor exhibited strong early enhancement followed by washout. Pathological and laparoscopic findings confirmed the coexistence of locally advanced prostate cancer and pelvic schwannoma. Conclusions: MRI is useful not only in detecting prostate cancer but also in differentiating lymph node metastases from schwannoma.
Neutrophil to Hemoglobin Lymphocyte Ratio (NHLR) as a Novel Biomarker is Superior to Neutrophil Lymphocyte Ratio (NLR) and Platelet Lymphocyte Ratio (PLR) as Predictors of Advanced Colorectal Cancer
Authors: Purnomo Heri , Handaya Yuda , Setyawan Nurcahya 
Published: March 2024

Background: Neutrophils, Hemoglobin, and Lymphocytes are biological markers that may be related to the colorectal cancer stage. Neutrophils to Hemoglobin-Lymphocytes Ratio (NHLR) is a new biomarker that will be tested with Neutrophil Lymphocyte Ratio (NLR) and Platelet Lymphocyte Ratio (PLR) as common biomarkers that have been shown to have predictive value with colorectal cancer stage. This study aims to prove NHLR as a new biomarker that can predict advanced colorectal cancer in terms of staging and site of cancer compared to NLR and PLR. Methods: This is a retrospective cross-sectional study. Data obtained from the medical records of colorectal cancer patients undergoing surgery at Dr Sardjito Hospital from 2020 until 2022. Results: 386 patients enrolled in the study, and 62 patients met the inclusion criteria. Twentyeight patients (45.16 %) were male, and 34 (54.84 %) were female. The mean age is 58.82 years. Bivariate analysis showed a significant relationship between NHLR, NLR, and PLR with colorectal cancer stage and significant differences between NHLR and NLR with early and advanced colorectal cancer, but not with PLR. There are also significant differences between NHLR, NLR, and PLR with colorectal cancer sites in the colon and rectum. Still, in locally advanced stages of colorectal cancer, there is no significant association between NLR and cancer sites. On the contrary, there are significant differences between colon and rectal cancer sites with NHLR and PLR. Conclusions: NHLR is superior to NLR and PLR in predicting the stage and site of advanced colorectal cancer.
Inhibition of corrosion on API 5L X52 pipeline steel in acid media by Tradescantia spathacea
Authors: Rodríguez-Torres Adriana , Valladares-Cisneros María Guadalupe , Chávez-Díaz German , Martínez-Calzada Víctor , Saldaña-Heredia Alonso 
Published: March 2024

The concentration effect of Tradescantia spathacea (T. spathacea) as corrosion inhibitor of API 5L X52 steel in 0.5 M of H2SO4 was studied here through electrochemical and gravimetric techniques. To achieve it, samples of the material were prepared to be submitted to each of the tests. Results from electrochemical impedance spectroscopy (EIS) showed that there was an optimum concentration of the inhibitor in which is reached the maximum inhibition efficiency, displaying the best inhibition characteristics for this system with a maximum inhibition of 89% by using 400 ppm. However, the efficiency decreased until 40% when the temperature was increased to 60°C. Potentiodynamic polarization curves (PDP) revealed that some of the present compounds of T. spathacea may affect anodic and cathodic process, so it can be classified as a mix-type corrosion inhibitor for API 5L X52 in sulfuric acid. Also, this compound followed an adsorption mechanism; this can be described through a Frumkin isotherm with an adsorption standard free energy difference (ΔG°) of −56.59 kJmol−1. Metal surface was studied through scanning electron microscope, results revealed that by adding inhibitor, the metal surface is protected; also, they evidenced low damages compared with the surface with no inhibitor. Finally, Tradescantia spathacea inhibited the corrosion process with 82% efficiency.