bluuebunny/crossref_metadata_2025_split huggingface dataset:
Re-Wetting Behavior and Heat Extraction during Laboratory-Scale Quenching Experiments using Two Probe Geometries
Authors: Cruces-Reséndez R. , Hernández-Morales B. , Durán García E.I. 
Published: March 2024

Abstract
The effect of probe geometry on the re-wetting behavior and heat extraction of cylindrical probes during forced convective quenching in laboratory-scale equipment was studied. Flat-end and hemispherical-end cylindrical probes made of AISI 304 stainless steel and instrumented with type-K thermocouples were considered. Two free-stream velocities (0.2 and 0.6 m/s) and two initial probe temperatures (850 and 950°C) were studied. The quench medium was water at 60°C. The inverse boiling curves and videos obtained showed that the vapor film stage lasts longer when using flat-end probes. This delay in the start of re-wetting shifted the cooling curves to the right and favored the probe surface to reach lower temperatures before the start of re-wetting which resulted in slightly higher values of the wetting front velocity. It is shown that the hydrodynamics of the flow around the probe end is responsible for the differences observed between the two geometries.
Aspects of Precise Heat Input Control for High-Frequency Welding
Authors: Frame Lesley D. , Davis Kevin , Tupalo Olexandra , Ignatowski Tom , Nallen Mick 
Published: March 2024

Abstract
High frequency welding is a thermo-mechanical process that relies on precise heat input as well as mechanical control as strip edges are heated and forged together to result in a seam weld. Heat input can be defined as a way of characterizing the temperature distribution at the strip edges prior to forging them together. Heat input is affected by several process variables ranging from raw material properties to welder settings and weld area setup. These are summarized in this paper, with special attention on the effects of welder frequency, welder power, line speed, and steel alloy composition on heat input and the resulting weld quality. Frequencies in the range of 100 – 800 kHz are considered. Data from tube mills (including general data and controlled on-the-mill experiments) and laboratory evaluations are included in this paper.
Super Hard WC Cermet Coating by Low Pressure Cold Spray Based on Optimization of Powder Properties
Authors: Sonoda T. , Kuwashima T. , Saito T. , Sato K. , Furukawa H. , Kitamura J. , Ito D. 
Published: March 2024

Abstract
In this work, tungsten carbide coatings are deposited by low-pressure cold spraying in order to assess the influence of powder compressive strength and binder materials on coating properties. Powder compressive strength was measured with a micro-compression tester, and cobalt and FeCr in different proportions were used as the metal binder. It was found that compressive strength affects coating hardness as well as deposition efficiency and that the optimum value for deposition efficiency is about 200 MPa. The results also indicate that dense coatings can be produced with either binder material, although coatings with an FeCr binder are the hardest.
A Numerical Study of Suspension Injection in Plasma Spraying Process
Authors: Jabbari F. , Jadidi M. , Wuthrich R. , Dolatabadi A. 
Published: March 2024

Abstract
This study compares two methods for modeling the breakup of droplets during suspension plasma spraying. One is based on Taylor analogy breakup, the other on Kelvin-Helmholtz Rayleigh Taylor breakup. A three-dimensional model with two-way coupling is used to simulate flow within the plasma plume and interactions between suspension droplets, and a Reynolds stress model is used to simulate gas field turbulence. After breakup and vaporization, the solid suspended particles are tracked through the domain to determine the characteristics of coating particles. The numerical results are validated against experiments using high-speed imaging.
Analysis of End-to-End Delay in the Transport Segment of Fronthaul 4G/5G Networks Based on TSN Technology
Authors: Roslyakov A. , Gerasimov V. 
Published: March 2024

One of the characteristic features of 4G/5G mobile networks is the spatial separation of functional blocks. The corresponding segments of the xHaul transport network are used to connect these blocks. One of them is the Fronthaul front end segment, which connects remote radio equipment with their control equipment. The data streams of standard CPRI/eCPRI radio interfaces in this segment impose strict requirements on the quality of service and, above all, on delays. To meet these requirements, it was proposed to use in the Fronthaul segment Ethernet bridge network based on the technology of time-sensitive networks TSN (Time Sensitive Networking), which provides determinated delays, reliable packet delivery and high accuracy of synchronization of nodes in the network. The IEEE 802.1CM standard describes profiles of TSN networks that defines the functions, options, configurations, default values, protocols and procedures of bridges, stations and local networks required to build the Fronthaul transport segment. The article presents a methodology for determining the maximum end-to-end traffic delays of standard CPRI/eCPRI radio interfaces in the Fronthaul segment of 4G/5G networks, built on the basis of TSN technology, in accordance with the requirements of IEEE 802.1CM standard. Two main components of end-to-end delay are identified ‒ delays in TSN bridges and delays in xEthernet channels. For high-priority traffic flows of CPRI/eCPRI radio interfaces in bridges, characteristic cases of mutual influence of flows arriving simultaneously at different input ports are given. An example of numerical calculation is given, which allowed to determine the permissible physical length of the Fronthaul segment at a given boundary end-to-end delay of transmission of high-priority traffic.
PENGARUH TINGKAT PEMBERIAN KONSENTRAT TERHADAP KUALITAS SUSU SAPI PERAH FH PERIODE LAKTASI KE-3
Authors: Rossiyanti Erri , Widyani Retno , Rusita Rusita 
Published: March 2024

AbstrakÂ Â Â Â Â Â Â Â Â Â Â Penelitian ini bertujuan untuk mengetahui tingkat pemberian konsentrat terbaik untuk mendapatkan produksi susu dengan kualitas yang baik dan pakan efisiens pada sapi perah di wilayah kerja KUD Karya Nugraha Kelurahan Cipari Kecamatan Cigugur Kabupaten Kuningan. Penelitian dilaksanakan selama 2 (dua) minggu yaitu 22 September -Â 4 Oktober 2008 di KUD Karya Nugraha Kelurahan Cipari Kecamatan Cigugur Kabupaten Kuningan dengan menggunakan 24 ekor sapi laktasi ke 3 yang diberi pakan rumput gajah dengan bahan kering BK 22,2 % dan kadar protein 8,69 % dan konsentrat dengan BK 87,3% dan kadar protein 18% dengan kombinasi pemberian sesuai perlakuan dan diulang 4 kali. Kombinasi pemberian pakan yaitu : A= Konsentrat 25% dari BK pakan; B = Konsentrat 30% dari BK; C=Konsentrat 35% dari BK; D = Konsentrat 40% dari BK; E=Konsentrat 45% dari BK; F=Konsentrat 50% dari BK. Hasil dari penelitian ini yaitu bahwa pemberian pakan konsentrat dengan kadar 40 â€“ 50% dari BK kebutuhan pakan menghsilkan susu sapi dengan kualitas yang baik sesuai dengan ketentuan Milk Codex yaitu Kadar lemak 3,68 â€“ 3,70 % , SNF 8% dengan pemberian pakan yang paling efisien.Kata Kunci : Konsentrat, Susu Sapi Perah FH dan laktasi ke-3
EVALUASI TINGKAT KEBERHASILAN INSEMINASI BUATAN (IB) PADA SAPI PERANAKAN ONGGOLE (PO) (STUDI KASUS DI KELOMPOK TANIâ€HARAPAN MULYAâ€ KABUPATEN KUNINGAN) TAHUN 2011 S/D 2013
Authors: Nuryamin Hadi , Widyani Retno , Sumardjo Djodjo 
Published: March 2024

ABSTRAKÂ Â Â Â Â Â Â Â Â Â Â Penelitian ini bertujuan untuk mengetahui jumlah straw yang digunakan untuk menghasilkan satu kebuntingan atau nilai Service per Conception (SC) pada pelaksanaaan Insemianasi Buatan dan persentase tingkat kebuntingan atau conception rate (CR), hasil Inseminasi Buatan (IB) pertama pada sapi peranakan Onggole (PO). Penelitian dilaksanakan di Kelompok tani â€œHARAPAN MULYAâ€ Desa Cipondok Kecamatan Cibingbin Kabupaten Kuningan dengan melakukan survey/observasi mengenai data pelaksanaan Inseminasi Buatan (IB) pada ternak sapi peranakan onggole (PO) dari tahun 2011 â€“ 2013 serta pengamatan lapangan. Data primer yang diamati adalah jumlah straw yang digunakan, jumlah ternak sapi yang di inseminasi dan jumlah ternak sapi yang bunting pada Inseminasi Buatan yang pertama. Hasil penelitian menunjukan bahwa pelaksanaan IB di Kelompok tani â€œHARAPAN MULYAâ€ Desa Cipondok Kecamatan Cibingbin Kabupaten Kuningan yang dilakukan oleh petugas / inseminator Dinas Pertanian Peternakan dan Perikanan Kabupaten Kuningan berhasil baik yaitu memiliki nilai Service per Conception (SC) 1,67 dan presentase kebuntingan atau nilai Conception Rate (CR) 60%.Kata kunci : Inseminasi Buatan (IB), Sapi PO, Service per Conception (SC)Â danÂ Conception Rate (CR)
STUDI PENGGUNAAN MIKROBIALTRANSGLUTAMINASE PADA PROSES PEMBUATAN KEJU DARI SUSU SAPI
Authors: Nilamcaya Mus 
Published: March 2024

ABSTRAK :Penelitian ini bertujuan mengevaluasi pengaruh penambahan enzim mikrobial transglutaminase (MTG) pada proses pembuatan keju segar dari susu sapi terhadap yield, komposisi dan karakteristik keju.Â Materi berupa susu sapi segar diperoleh dari Experimental Farm, Fakultas Peternakan. Enzim yang digunakan adalah water solutionMTG (Activa TG-BW-MH), dan mikrobial rennet berbentuk tablet kering. Penelitian dilaksanakan secara eksperimental dengan Rancangan Acak Lengkap (RAL). Terdapat 5 macam perlakuan yang diuji, yang meliputi penambahan MTG sebanyak 0,1; 0,2; 0,3 dan 0,4% (w/w) dari bobot susu sapi yang digunakan; dengan satu perlakuan kontrol yaitu tanpa penambahan MTG. Penambahan MTG dilakukan pada susu pasteurisasi (suhu 50oC), kemudian susu didiamkan selama satu jam. Selanjutnya, susu ditambah dengan kultur cair bakteri asam laktat dan diinkubasi selama 2 jam pada suhu 37oC, kemudian ditambah dengan koagulan (rennet). Masing-masing perlakuan diulang sebanyak 4 kali.Hasil penelitian menunjukan bahwa penambahan MTG sampai level 0,4% pada proses pembuatan keju dapat meningkatkan yield Â sampai 34%, namun peningkatan level MTG dari 0,1% sampai dengan 0,4% tidak memberikan pengaruh yang nyata. Penambahan MTG meningkatkan kadar air, namun di sisi lain menurunkan kadar protein keju. Kadar lemak dan mineral keju yang dibuat dengan penambahan MTG menunjukan nilai yang relatif sama dengan kontrol. Sama halnya dengan yield, peningkatan level MTG dari 0,1% sampai dengan 0,4% tidak memberikan pengaruh yang nyata terhadap kadar air, protein, lemak dan mineral. Tingkat keasaman (pH) keju dan whey tidak dipengaruhi oleh penambahan MTG. Pengamatan secara visual menunjukan bahwa whey dari proses pembuatan keju yang ditambah MTG terlihat lebih jernih dibandingkan dengan kontrol. Berdasarkan hasil tersebut, dapat disimpulkan bahwa penambahan MTG pada proses pembuatan keju segar dari susu sapi mampu meningkatkan yield namun tidak banyak mempengaruhi komposisi dan karakteristik keju.Kata kunci :Â Â susu sapi, mikrobial transglutaminase, keju,Â whey,Â yield
Entering China’s emerging life sciences markets: The opportunity for Ontario startups
Authors: Kim Chris 
Published: March 2024

<p>This report examines the market opportunities in China for Ontario life sciences startups, as well as issues around market access. Entering China’s market can present numerous challenges for life sciences startups until they become familiar with the market and its related funding opportunities. The report also explores the concerns of Ontario startups about venturing into China’s markets, including a look at intellectual property (IP) protection, regulation hurdles and collaboration models. </p>
<p>This publication is the second part of a series produced by MaRS called Going Global: China. Download the earlier report, Playing the Long Game: China’s market opportunities for Ontario startups </p>
Beyond embedded: Blended roles for information professionals in the 21st century knowledge economy
Authors: Chung Hyun-Duck , Kim Chris , Kula Helen 
Published: March 2024

<p>Twenty-first century librarians work with diverse populations with a variety of needs. Information users take multiple roles and institutional affiliations, collaborating across disciplines and domains of expertise. Librarians at the Gerstein Science Information Centre (Gerstein) of the University of Toronto Libraries (UTL) in Ontario, Canada have embraced the challenge of providing services that not only expand across traditional boundaries of public, academic and corporate information services, but also reach beyond a local user base. They meet this challenge by taking on embedded and blended roles as market intelligence information specialists at the MaRS Discovery District (MaRS), an innovation centre that works closely with the University of Toronto community. Working as a cohesive team, information specialists and industry analysts at MaRS serve clients that have diverse information needs, which span multiple industry sectors: information, communications and entertainment; life sciences; clean-tech and advanced manufacturing & materials; and social innovation. In the absence of a physical library, the market intelligence team leverages proprietary electronic subscriptions and publicly available information to deliver quality information services in a unique and sustainable way. This chapter will provide a case study that examines the growth of the operation from a single information specialist to a larger team over time, explains the current structure of the team, and explores the complementary strengths and skill sets of the various team members. </p>
Study on the Utilization of Itchy Leaf Plants (laportea sp.) By the Community of Bariat Village, Konda District South Sorong Regency
Authors: Irnawati Irnawati , Soekamto Mira Herawati , Hidaya Nur 
Published: March 2024

Itchy leaves are a kind of herbaceous plant that comes from the Urticaceae family where if applied all over the body it will cause a very itchy effect. After the itchy sensation for 5 minutes, the pain and sore effects will work very effectively. The local Papuan people, especially the South Sorong area, are active in using itchy leaves as an effective traditional medicine to cure muscle pain, but until now it has not been known to identify the types of itchy leaves used by local people. This research examines the identification of the types of itchy leaves plants used. The methods used as aspects of the utilization of Itchy Leaf plants are observation, interviews, and filling out questionnaires. While the results of the study showed that there were three types of Itchy Leaf plants in Bariat Village, Konda District which belonged to 1 (one) family, namely Urticaceae. There are 3 types of itchy leaves, namely Laportea decumana (kafa'), Laportea stimulants syn (kafasa), and Laportea peltata (Kafa'). Furthermore, this group of Itchy Leaf plants is used by the community by rubbing, squeezing the leaves, wrapping and as a trap for wild animals.
Impact of a combination sound therapy on tinnitus distress: an exploratory one-year longitudinal study
Authors: Lelic Dina , Caporali Sueli , Parker Daniel , Nielsen Jakob , Balling Laura Winther 
Published: March 2024

IntroductionCombination devices offering both amplification and sound therapy are commonly used in tinnitus management. However, there is insufficient evidence supporting the relationship between sound therapy and tinnitus outcomes. The aim of this study was to explore longitudinal effects of sound therapy on tinnitus-related distress using a combination device.MethodTwenty participants with mild to moderate tinnitus related distress were fitted with combination devices that included three sound-therapy programs. The sound-therapy programs were selected by the participants from the available sounds offered in the combination device. The sounds comprised fractal music, nature sounds and combinations of the two. Participants were asked to wear the devices for 12 months and to complete questionnaires related to tinnitus distress at baseline and 1, 2, 4, 6, and 12 months after starting the treatment. Additionally, at 2, 4, 6, and 12 months, the device log data capturing information about amplification and sound-therapy use were collected.ResultsTinnitus handicap inventory (THI), tinnitus functional index (TFI), tinnitus awareness and annoyance decreased following the device fitting. This improvement plateaued at 4 months. The degrees of improvement in THI, TFI and tinnitus annoyance were correlated with daily hours of sound-therapy use but not with daily hours of amplification-only or total device use.ConclusionsA combination sound therapy consisting of therapy sounds, amplification as needed, and counseling was associated with a reduction in tinnitus-related distress. A future randomized controlled trial should be conducted to allow for detangling the effect of sound therapy from effects of amplification, counseling, placebo, and time itself, and to investigate the predictors of sound-therapy benefit and use.
The effect of SARS-CoV-2 infection and vaccination on Th17 and regulatory T cells in a pregnancy cohort in NYC
Authors: Gigase Frederieke A. J. , Graziani Mara , Castro Juliana , Lesseur Corina , Rommel Anna-Sophie , Flores Tammy , Perez-Rodriguez M. Mercedes , Dolan Siobhan , Stone Joanne , Janevic Teresa , Lieb Whitney , Bergink Veerle , de Witte Lot D. 
Published: March 2024

Disturbances in T-cells, specifically the Th17/Treg balance, have been implicated in adverse pregnancy outcomes. We investigated these two T-cell populations following pre-pregnancy and pregnancy SARS-CoV-2 infection and COVID-19 vaccination in 351 participants from a pregnancy cohort in New York City (Generation C; 2020-2022). SARS-CoV-2 infection status was determined via laboratory or medical diagnosis and COVID-19 vaccination status via survey and electronic medical records data. Peripheral blood mononuclear cells (PBMCs) were collected at routine prenatal visits throughout gestation (median 108 days; IQR 67-191 days) with repeated measures for 104 participants (29.6%). T-cell populations CD4+/CD3+, Th17/CD4+, Treg/CD4+ and the Th17/Treg ratio were quantified using flow cytometry. Results showed that inter-individual differences are a main influencing factor in Th17 and Treg variance, however total variance explained remained small (R2 = 15-39%). Overall, Th17 and Treg populations were not significantly affected by SARS-CoV-2 infection during pregnancy in adjusted linear mixed models (p&gt;0.05), however comparison of repeated measures among SARS-CoV-2 infected participants and non-infected controls suggests a relative increase of the Th17/Treg ratio following infection. In addition, the Th17/Treg ratio was significantly higher after SARS-CoV-2 infection prior to pregnancy (10-138 weeks) compared to controls (β=0.48, p=0.003). COVID-19 vaccination was not associated with Th17 and Treg cells. Our findings suggest an impact of SARS-CoV-2 infection on the Th17/Treg ratio, likely depending on severity of infection, yet the observed trends and their potential consequences for pregnancy outcomes require further investigation. Our study contributes to growing evidence that COVID-19 vaccination during pregnancy does not lead to an exacerbated immune response.
Insecticide paints: a new community strategy for controlling dengue and zika mosquito vectors in Cabo Verde
Authors: Gómez Lara Ferrero , Rocha Hélio D. Ribeiro , Torró Ignacio Gil , Pérez Irene Serafín , Mendes Deinilson Conselheiro , Silva Keily L. Fonseca , Monteiro Davidson D. Sousa Rocha , Dos Reis Jailson P. Tavares , Leal Silvânia Veiga , Soulé Luis F. Vitória , Fortes Jailton C. , Mendonça Maria da Luz Lima , Mendez Eva Caballero , Hernández Basilio Valladares 
Published: March 2024

BackgroundCabo Verde, an island country in West Africa, has been affected since human colonization by epidemics of vector-borne diseases with major epidemics of dengue and zika in recent years. Although there is a national program for integrated vector control, innovative strategies that reinforce routine activities and strengthen vector control are necessary to prevent the emergence or reemergence of arboviruses and new epidemics of dengue and zika. Insecticide paints are evidenced as new technologies for the formulation of insecticides in a more residual and safe way. The TINTAEDES project aimed to assess the efficacy, acceptability, and operational deployment of an insecticide paint for Aedes control.Methodology/Principal findingsLaboratory and small-scale field trials were conducted, assessing mortality through World Health Organization cone bioassays. A community-based intervention study in the neighborhoods of Várzea and Tira Chapéu in the city of Praia, Cabo Verde, was developed. The intervention is a paint self-application model by homeowners and neighborhood volunteers. The intervention was evaluated based on entomological indicators and the responses given by the residents of the painted houses to a questionnaire on the knowledge, satisfaction, and safety of insecticidal paints. A transfluthrin-based insecticide paint was effective against wild Ae. aegypti for one year in the laboratory and semi-field conditions. Residents largely perceived a reduction in mosquito presence in the treated houses (98%).ConclusionInsecticide paints are presented as an effective innovation strategy for mosquito control, which could be implemented as a reinforcement of the measures carried out by the vector control program in the city of Praia and throughout the country.
5-HT1F receptor agonism induces mitochondrial biogenesis and increases cellular function in brain microvascular endothelial cells
Authors: Scholpa Natalie E. , Simmons Epiphani C. , Thompson Austin D. , Carroll Seth S. , Schnellmann Rick G. 
Published: March 2024

IntroductionVascular and mitochondrial dysfunction are well-established consequences of multiple central nervous system (CNS) disorders, including neurodegenerative diseases and traumatic injuries. We previously reported that 5-hydroxytryptamine 1F receptor (5-HT1FR) agonism induces mitochondrial biogenesis (MB) in multiple organ systems, including the CNS.MethodsLasmiditan is a selective 5-HT1FR agonist that is FDA-approved for the treatment of migraines. We have recently shown that lasmiditan treatment induces MB, promotes vascular recovery and improves locomotor function in a mouse model of spinal cord injury (SCI). To investigate the mechanism of this effect, primary cerebral microvascular endothelial cells from C57bl/6 mice (mBMEC) were used.ResultsLasmiditan treatment increased the maximal oxygen consumption rate, mitochondrial proteins and mitochondrial density in mBMEC, indicative of MB induction. Lasmiditan also enhanced endothelial cell migration and tube formation, key components of angiogenesis. Trans-endothelial electrical resistance (TEER) and tight junction protein expression, including claudin-5, were also increased with lasmiditan, suggesting improved barrier function. Finally, lasmiditan treatment decreased phosphorylated VE-Cadherin and induced activation of the Akt-FoxO1 pathway, which decreases FoxO1-mediated inhibition of claudin-5 transcription.DiscussionThese data demonstrate that lasmiditan induces MB and enhances endothelial cell function, likely via the VE-Cadherin-Akt-FoxO1-claudin-5 signaling axis. Given the importance of mitochondrial and vascular dysfunction in neuropathologies, 5-HT1FR agonism may have broad therapeutic potential to address multiple facets of disease progression by promoting MB and vascular recovery.