bluuebunny/crossref_metadata_2025_split huggingface dataset:
Comparative decay resistance of plantation-grown and naturally-grown teak wood (Tectona grandis L.f.)
Authors: YAMAMOTO Koichi 
Published: March 2024

Teak (Tectona grandis L.f.) is one of the most popular tropical timber species for its natural durability. The sapwood, the outer, middle, and inner heartwood, and the pith of plantation-grown teak in Indonesia and naturally grown teak in Myanmar were tested for decay resistance (a major component of natural durability), applying an accelerated decay test according to JIS Z 2101 (1994), and using a white rot fungus (Trametes versicolor) and a brown rot fungus (Fomitopsis palustris). Wood blocks 20 × 20 × 10 mm in size were cut from discs across the radius of the stem. The percentage mass loss in each block caused by decay was obtained after 12 weeks of incubation with these fungi. Mean mass losses due to T. versicolor were respectively as follows for plantation-grown, naturally-grown (No. 1), and naturally-grown (No. 2) teak: sapwood 21.4%, 7.1%, “no data”; outer heartwood 0.6%, 3.6%, 6.6%; middle heartwood 2.3%, 6.5%, 5.7%; inner heartwood 10.3%, 9.6%, 6.0%; pith 13.0%, 15.3%, 8.2%. Losses due to F. palustris were, respectively: sapwood 7.5%, 3.0%, 7.5%; outer heartwood 0.0%, 2.5%, 2.7%; middle heartwood 0.0%, 2.2%, 2.3%; inner heartwood 4.9%, 2.0%, 3.4%; pith 13.6%, 8.4%, 8.0%. Durability was classified with reference to Osborne (1970), based on the mean percentage weight loss of heartwood caused by fungal decay. Only the outer and middle heartwood were generally durable in both plantation-grown and naturally grown teak specimens. The inner heartwood was moderately durable, but pith durability was low. No clear differences in decay resistance were found between plantation-grown and naturally-grown teak.
El repudio en los Códigos de familia de Túnez, Marruecos, Argelia, Emiratos Árabes Unidos y Jordania
Authors: Cervilla Garzón María Dolores 
Published: March 2024

Este trabajo realiza un estudio comparativo desde una perspectiva de género de la regulación del repudio en los Códigos de familia de Túnez, Marruecos, Argelia, Jordania y Emiratos Árabes.
I. Zurita Martín y M.D. Cervilla Garzón (Dirs.). Identidad islámica y orden público en una sociedad inclusiva.
Authors: Rodríguez Benot Andrés 
Published: March 2024

Este artículo reseña:
I. Zurita Martín y M.D. Cervilla Garzón (Dirs.). Identidad islámica y orden público en una sociedad inclusiva. Aranzadi, Cizur Menor, 2023. ISBN: 978-84-1163-064-1
Are people willing to pay for carbon neutrality? A survey from urban residents in Zhejiang, China
Authors: dong xuewang , huang huating , shao mengting , zhi ruizhi 
Published: March 2024

Abstract
Consumer responsibility is an important theoretical perspective for realizing China’s “carbon neutrality” policy goals. A theoretical model was developed based on the value-belief-norm perspective and the theory of planned behavior to estimate urban residents’ willingness to pay (WTP) for carbon neutrality. Based on the contingent valuation method, a single-bounded dichotomous choice elicitation format was used in the questionnaire survey, and 2,040 samples of urban family households in Zhejiang Province were randomly sampled. Subsequently, a binary logistic regression model was employed to estimate the carbon-offsetting WTP among urban households, and the influencing factors were analyzed. The study revealed that urban households in Zhejiang Province were willing to pay $11 per month and household to achieve carbon neutrality, and the respondents’ WTP for carbon offsetting was significantly affected by ascription of responsibility, subjective norms, age, income, and occupation. However, environmental values, attitudes, personal norms, an awareness of consequences, and education level did not significantly affect the respondents’ WTP. Finally, this study provides supporting data and policy suggestions for the formulation of more effective and reliable carbon offsetting standards and the realization of carbon neutrality goals in China.
Correlates of small screens play in 6–10-year-old children in China
Authors: Chen Lijian , liao jinjin , Ye Sunyue 
Published: March 2024

Abstract

IMPORTANCE Most of the current studies focus on fixed screens. However, the small mobile devices have been widely used among children of a younger age.
OBJECTIVE The aim of this study was to explore the factors associated with small screen use and its duration among first and second grade elementary school students based on Chinese cross-sectional data.
DESIGN, SETTING, AND PARTICIPANTS A total of 1121 students aged 6-10 years were recruited for this study. Logistic regression model was used to analyze the influencing factors of whether students use small screen devices and linear regression model was used to analyze the influencing factors of students' small electronic screen time. The data analysis spanned from August 21, 2023, to January 1, 2024.
EXPOSURES A questionnaire was used to collect basic information about students and parents and the use of small screens.
MAIN OUTCOMES AND MEASURES Recommendations for students' scientific use of small screen time in response to survey results.
RESULTS Girls (OR=0.74, p=0.035), having their own mobile phone (OR=3.66, p<0.001), unclear screen rules (OR=1.45, p<0.001), father's education level (OR=0.49, p=0.033), and mother's weekend screen time (<1 h/d as the reference group) 1-2 h/d (OR=2.49, p=0.001), 2-3 h/d (OR=2.7, p=0.001), ≥3 h/d (OR=2.27, p=0.009) were significantly associated with students’ use on screens. For total time (weekdays + weekends), girls spent more time on small screens compared to boys (β=58.88, p=0.043); having their own mobile phone or tablet computer (β=65.47, p=0.026), the less clear the family's screen time rules (β=60.55, p<0.001), and the longer mother's weekend screen time (β=142.61, p=0.027) were associated with longer total screen time for students.
CONCLUSIONS AND RELEVANCE Availability of their own small electronic devices, clarity of screen rules, father's education, and mother's weekend screen time were significantly correlated with students' screen time in China. Future studies with longitudinal design are needed.
Clinical study of plasma lymphocyte subsets and inflammatory factors in patients with acute coronary syndrome after COVID-19(omicron variant)infection
Authors: Liu Ran , Li Zixuan , Hou Yanjun , Zhai Guangyao 
Published: March 2024

Abstract
Background:The Omicron variant is the main circulating strain by the end of 2022,our study is to reveal the possible impact of COVID-19(Omicron variant) infection on ACS patients Through researching the changes of lymphocyte subsets and inflammatory factors.
Methods:This is a case-control study. 234 patients of COVID-19 infection accompany with acute coronary syndrome were enrolled,78 patients with only COVID-19 infection were enrolled as controls. Flow cytometry was used to detect lymphocyte subsets, Chemiluminescence assay was used to measure IL-6, IL-8, and TNF-α levels. The above indexes were compared in three groups during different stage of COVID-19 infection.
Results: 1) Compared with the control group,after COVID-19 infection,the STEMI and NSTE-ACS groups both showed a decrease in CD4+ T lymphocytes，while an increase in IL-6 and TNF-α levels only in STEMI group (P<0.05); Furtherly Within 3 months of COVID-19 infection,the STEMI group showed a decrease in CD4+ and CD8+ T lymphocytes, and an increase in CD4+/CD8+, IL-6, and TNF-α (P<0.05), while only CD4+ T decreased in the NSTE-ACS group (P<0.05); But after 3 months of COVID-19 infection, only the STEMI group showed a significant increase in IL-6 and TNF-α (P<0.05).2)Compared with the NSTE-ACS group, the STEMI group showed a significant decrease in CD8+ T lymphocytes and an increase in CD4+/CD8+ T lymphocytes within 3 months of COVID-19 infection(P<0.05)
Conclusions:Patients with a decrease in CD4+ T lymphocytes after COVID-19 infection maybe more prone to combined withacute coronary syndrome. Patients who develop STEMI within 3 months of COVID-19 infection may have a poorer prognosis.
Locus coeruleus injury modulates ventral midbrain neuroinflammation during DSS-induced colitis
Authors: Tansey Malú Gámez , Boles Jake , Holt Jenny , Cole Cassandra , Neighbarger Noelle , Urs Nikhil , Uriarte-Huarte Oihane 
Published: March 2024

Abstract
Parkinson’s disease (PD) is characterized by a decades-long prodrome, consisting of a collection of non-motor symptoms that emerges prior to the motor manifestation of the disease. Of these non-motor symptoms, gastrointestinal dysfunction and deficits attributed to central norepinephrine (NE) loss, including mood changes and sleep disturbances, are frequent in the PD population and emerge early in the disease. Evidence is mounting that injury and inflammation in the gut and locus coeruleus (LC), respectively, underlie these symptoms, and the injury of these systems is central to the progression of PD. In this study, we generate a novel two-hit mouse model that captures both features, using dextran sulfate sodium (DSS) to induce gut inflammation and N-(2-chloroethyl)-N-ethyl-2-bromobenzylamine (DSP-4) to lesion the LC. We first confirmed the specificity of DSP-4 for central NE using neurochemical methods and fluorescence light-sheet microscopy of cleared tissue, and established that DSS-induced outcomes in the periphery, including weight loss, gross indices of gut injury and systemic inflammation, the loss of tight junction proteins in the colonic epithelium, and markers of colonic inflammation, were unaffected with DSP-4 pre-administration. We then measured alterations in neuroimmune gene expression in the ventral midbrain in response to DSS treatment alone as well as the extent to which prior LC injury modified this response. In this two-hit model we observed that DSS-induced colitis activates the expression of key cytokines and chemokines in the ventral midbrain only in the presence of LC injury and the typical DSS-associated neuroimmune is blunted by pre-LC lesioning with DSP-4. In all, this study supports the growing appreciation for the LC as neuroprotective against inflammation-induced brain injury and draws attention to the potential for NEergic interventions to exert disease-modifying effects under conditions where peripheral inflammation may compromise ventral midbrain dopaminergic neurons and increase the risk for development of PD.
Predictors of functional improvement and pain reduction in rheumatoid arthritis patients who achieved low disease activity with disease-modifying antirheumatic drugs: a retrospective study of the FIRST Registry
Authors: Ochi Sae , Sonomoto Koshiro , Nakayamada Shingo , Tanaka Yoshiya 
Published: March 2024

Abstract

Background
Rheumatoid arthritis (RA) patients sometimes different levels of improvement in health assessment questionnaire-disability index (HAQ-DI) and subjective pain visual analogue score (VAS) even after achieving low disease activities (LDA). This study aimed to identify factors associated with improvement in HAQ-DI and pain VAS among those who achieved LDA.
Methods
Data of the FIRST registry, a multi-institutional cohort of RA patients treated with biological and targeted-synthetic DMARDs (b/tsDMARDs) were analyzed. Patients who were enrolled from August 2013 to February 2023 and who achieved clinical LDA [clinical disease activity index (CDAI) ≤ 10.0] at 6 months after starting treatment were included. Multiple logistic regression analyses were conducted to identify the factors that associated with achieving HAQ-DI normalization (< 0.5), HAQ-DI improvement (by > 0.22), or pain VAS reduction (≤ 40mm).
Results
Among 1424 patients who achieved LDA at 6 months, 732 patients achieved HAQ-DI < 0.5 and 454 achieved pain VAS reduction. The seropositivity and the use of JAK inhibitor compared with TNF inhibitor were associated with both HAQ-DI < 0.5 and pain VAS reduction at 6 months. On the other hand, older age, past failure in ≥ 2 classes of b/tsDMARDs, higher HAQ-DI at baseline, and use of glucocorticoid were associated with the lower likelihood of HAQ-DI normalization and pain VAS reduction. Longer disease duration, being female, and higher disease activity at baseline was negatively associated HAQ-DI normalization alone. Comorbidities were not associated with the outcomes.
Conclusions
These results suggest some preferable treatment may exist for improvement of HAQ-DI and pain VAS reduction in the early stage of the treatment, which is a clue to prevention of a criteria of difficult-to-treat RA.
Topology-enhanced machine learning for consonant recognition
Authors: Zhu Yifei , Feng Pingyao , Yi Siheng , Qu Qingrui , Yu Zhiwang 
Published: March 2024

Abstract
In artificial-intelligence-aided signal processing, existing deep learning models often exhibit a black-box structure. The integration of topological methods serves a dual purpose of making models more interpretable as well as extracting structural information from time-dependent data for smarter learning. Here, we provide a transparent and broadly applicable methodology, TopCap, to capture topological features inherent in time series for machine learning. Rooted in high-dimensional ambient spaces, TopCap is capable of capturing features rarely detected in datasets with low intrinsic dimensionality. Compared to prior approaches, we obtain descriptors which probe finer information such as the vibration of a time series. This information is then vectorised and fed to multiple machine learning algorithms. Notably, in classifying voiced and voiceless consonants, TopCap achieves an accuracy exceeding 96%, significantly outperforming traditional convolutional neural networks in both accuracy and efficiency, and is geared towards designing topologically enhanced convolutional layers for deep learning speech and audio signals.
Mechanistic Analysis of Riboswitch Ligand Interactions Provides Insights into Pharmacological Control over Gene Expression
Authors: Schneekloth John , Parmar Shaifaly , Bume Desta , Connelly Colleen , Boer Robert , Prestwood Peri , Wang Zhen , Labuhn Henning , Sinnadurai Krishshanthi , Feri Adeline , Ouillet Jimmy , Homan Philip , Numata Tomoyuki 
Published: March 2024

Abstract

Riboswitches are structured RNA elements that regulate gene expression upon binding to small molecule ligands. Understanding the mechanisms by which small molecules impact riboswitch activity is key to developing potent, selective ligands for these and other RNA targets. We report the structure-informed design of chemically diverse synthetic ligands for PreQ1 riboswitches. Multiple X-ray co-crystal structures of synthetic ligands with the Thermoanaerobacter tengcongensis (Tte)-PreQ1 riboswitch confirm a common binding site with the cognate ligand, despite considerable chemical differences among the ligands. Structure probing assays demonstrate that one ligand causes conformational changes similar to PreQ1 in six structurally and mechanistically diverse PreQ1 riboswitch aptamers. Single-molecule force spectroscopy is used to demonstrate differential modes of riboswitch stabilization by the ligands. Binding of the natural ligand brings about the formation of a persistent, folded pseudoknot structure, whereas a synthetic ligand decreases the rate of unfolding through a kinetic mechanism. Single round transcription termination assays show the biochemical activity of the ligands, while a GFP reporter system reveals compound activity in regulating gene expression in live cells without toxicity. Taken together, this study reveals that diverse small molecules can impact gene expression in live cells by altering conformational changes in RNA structures through distinct mechanisms.
Prediction of attention deficit hyperactivity disorder based on explainable artificial intelligence
Authors: Navarro-Soria Ignasi , Rico-Juan Juan Ramón , de Mier Rocío Juárez-Ruiz , Lavigne-Cerván Rocío 
Published: March 2024

Abstract

The aim of this study is to predict the probability being diagnosed with ADHD using ML algorithms and to explain the behavior of the model to support decision making. The dataset studied included 694 cases. Information was obtained on age, sex and WISC-IV scores. Algorithms belonging to different ML learning styles were tested. A stratified 10-fold-cross-validation was applied to evaluate the models. The metrics were used: accuracy, area under the receiver operating characteristic, sensitivity and specificity. We compared models using all initial features and a suitable wrapper-type feature selection algorithm. After, we calculated Shapley additive values to assign weights to each predictor based on its additive contribution to the outcome and explain the predictions. The Random Forest algorithm performed best on most metrics. The main predictors included, GAI-CPI, WMI, CPI, PSI, VCI, WMI - PSI, PRI and LN. The ML model adequately predicted ADHD diagnosis in 90% of cases.
Return-To-Work after mental illness: A qualitative study on factors promoting the reintegration into work
Authors: Braunwarth Sabrina , Lange Martin 
Published: March 2024

Abstract
Background: Mental illnesses have increased significantly in the past years and have a significant impact on individuals and work. Return-to-work (RTW) processes facilitate employees' return to work, help them regain workability, and prevent early retirement and long-term incapacity for work. However, the current state of evidence regarding RTW in the context of mental illness is not sufficient. The study aimed to identify (1) promoters and inhibitors of vocational rehabilitation from the patient's perspective, (2) potential differences in respondents' perceptions of various contextual factors, and (3) the relevance of professional, social, or economic influences on RTW acceptance.
Methods: The qualitative design used semi-standardized interviews. In total, eight people affected by mental illness were interviewed, of which seven were included in the thematic analysis. The interviews were conducted by the same person, either in person or by telephone. We used MaxQDA to develop a coding scheme in iterative revisions. Two additional independent individuals checked the final coding tree and data analysis.
Results: We identified, among other aspects, relationships with coworkers and supervisors, open communication about illness, or contact with peers as promotors of successful RTW. Inhibitors were triggers at the workplace, conflicts with supervisors, performance pressure, and a lack of understanding. Social support through family and daily routines were considered critical contextual factors. The constant justification of the illness or financial worries, e.g., were perceived as onerous. The exchange with peers and the role of stakeholders were revealed to be critical for a positive perception of the RTW process.
Conclusion: Our study showed that the return to work after or during a mental illness is a complex part of therapy. Work itself is an essential part of recovery after mental illness that can provide stability for those affected and minimize risk factors and remissions. This, in turn, assigns workplaces the role of a support system, including team members, supervisors, and daily routines and tasks. Our results underline that there is a collective responsibility for all stakeholders.
Translation, cross-cultural adaptation, validation, and reliability study of the Breast Cancer Fear Scale: Chinese version
Authors: Zhou Yanni , Li Xiaoxia , Lai Jie , Xiao Xiuyun , Wu Yanni 
Published: March 2024

Abstract

Background
Cancer-related fear has been identified as an important component of health-related behaviors. However, there is a lack of tools for measuring breast cancer fear in the Chinese healthcare context, which might hinder related studies in the Chinese population. The Breast Cancer Fear Scale developed by Champion was introduced, and its psychometric characteristics and factor structure were evaluated to provide a suitable and reliable measurement tool in China to assess the fear of breast cancer in Chinese women.
Methods
According to the Brislin back translation model, the Breast Cancer Fear Scale was translated into Chinese, 33 subjects were selected for the cognitive survey, 8 experts were invited for the content validity test, 245 subjects were surveyed via the convenience sampling method, and the reliability and validity of the scale were tested.
Results
The Chinese version of the Breast Cancer Fear Scale has 8 items in total. The content validity of the scale is 0.99, and the content validity of the item is 0.88 ~ 1.0. The expert's judgment basis (Ca) is 0.91, the expert's familiarity level (Cs) is 0.80, and the expert's authority coefficient (Cr) is 0.86. The Cronbach's α of the scale is 0.97. The retest reliability was 0.95. The project analysis shows that there are differences between groups, indicating that the discrimination of each item is good.
Conclusions
The Chinese version of the Breast Cancer Fear Scale has good reliability and validity and can be used to assess the fear of breast cancer in Chinese adult women.
Is poor oral health a risk factor for idiopathic granulomatous mastitis?
Authors: SAĞLIK Semih , Olgaç Şilan Bilek 
Published: March 2024

Abstract
OBJECTIVE:
Idiopathic granulomatous mastitis is a rare inflammatory disease of the breast that clinically and radiologically can be confused with carcinoma. Although its etiology remains unclear, it is stated that it may be related to pregnancy, lactation, hormonal imbalance, autoimmunity, smoking, α1-antitrypsin deficiency and various microorganisms. This study aimed to evaluate the relationship between idiopathic granulomatous mastitis and oral health.
PATIENTS AND METHODS:
Our study included 42 female patients diagnosed with idiopathic granulomatous mastitis as a result of histopathological evaluations between September 2018 and October 2023. The reference group consisted of 47 female patients with clinically, radiologically and laboratory proven non-specific mastitis and 36 healthy female individuals. The oral health of all individuals included in the study was evaluated by an experienced dentist using "Decayed, Missing and Filled Teeth" (DMFT) and "Simplified Oral Hygiene Index" (OHI-S) index values.
RESULTS:
The ages of idiopathic granulomatous mastitis patients included in the study ranged between 29-51 years (mean age 34.88±4.87). The most common clinical findings were pain (n=38), palpable breast mass (n=32), erythema (n=22), induration (n=14) and dermal sinus (n=10). When OHI-S and DMFT index values of the individuals included in the study were compared, both OHI-S and DMFT index values of individuals diagnosed with idiopathic granulomatous mastitis were statistically significantly higher than those of the reference group (p<0.05).
CONCLUSIONS
Our findings suggest that poor oral health may be involved in the etiology of idiopathic granulomatous mastitis. Therefore, it may be useful to consider oral health in the etiology of IGM in future studies and to investigate oral microbiota in samples obtained from the target tissue.