bluuebunny/crossref_metadata_2025_split huggingface dataset:
ChemInform Abstract: A 4‐Aminobenzoic Acid Derivative as Novel Lead for Selective Inhibitors of Multidrug Resistance‐Associated Proteins.
Authors: Leyers Stefan , Haecker Hans‐Georg , Wiendlocha Jeanette , Guetschow Michael , Wiese Michael 
Published: December 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Diphosphites Derived from 1,3:1′,3′‐Di‐O‐benzylidenedipentaerythritol—Key Synthons for New Types of Phosphorus‐Containing Compounds.
Authors: Predvoditelev D. A. , Malenkovskaya M. A. , Nifant'ev E. E. 
Published: December 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: A Convenient Synthesis of Novel 7‐Phosphonylbenzyl‐2‐Substituted Pyrazolo[4,3e]‐1,2,4‐triazolo[1,5‐c]pyrimidine Derivatives.
Authors: Xiao Lin‐Xia , Li Ke , Meng Liu , Shi De‐Qing 
Published: December 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis and Reactions of 2‐(Dimethylaminomethylidene)‐6‐methoxynaphtho[1,8‐bc]pyran‐3‐one.
Authors: Golyanskaya O. M. , Voloshin N. A. , Chernyshev A. V. , Dubonosov A. D. , Metelitsa A. V. , Mezheritskii V. V. , Bren' V. A. 
Published: December 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Tandem Molecular Rearrangement in the Alkylation of Phenol with Camphene.
Authors: Chukicheva I. Yu. , Spirikhin L. V. , Kuchin A. V. 
Published: December 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Norditerpenoid Alkaloids from Aconitum septentrionale K
Authors: Khairitdinova E. D. , Tsyrlina E. M. , Spirikhin L. V. , Balandina A. A. , Latypov Sh. K. , Yunusov M. S. 
Published: December 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Oct‐2‐en‐4‐ynoyl‐CoA as a Specific Inhibitor of Acyl‐CoA Oxidase.
Authors: Zeng Jia , Wu Long , Zhang Xiaojian , Liu Yuandong , Deng Guisheng , Li Ding 
Published: December 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Palaeophytochemical Constituents from the Miocene‐Fossil Wood of Picea likiangensis in Xun‐Dian of Yunnan, China.
Authors: Zhao You‐Xing , Luo Jian‐Rong , Li Cheng‐Sen , Yi Tie‐Mei , Zhou Jun 
Published: December 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthetic Studies on Soraphen A: Synthesis of the C1—C9 Hemiketal Segment.
Authors: Park Se Hwan , Lee Hyo Won 
Published: December 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis of the Pyridone Analogues of Territrem B.
Authors: Yang Yinghua , Sun Lianli , Dong Shengyi , Wang Xiaoyu , Yang Leixiang , Wu Xiumei , Bai Hua , Zhao Yu 
Published: December 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Discovery and Synthesis of Novel N‐Cyanopyrazolidine and N‐Cyanohexahydropyridazine Derivatives as Cathepsin Inhibitors.
Authors: Song Jong Hwan , Kim Sun Gi , No Zae Sung , Hyun Young‐Lan , Jeon Dong Ju , Kim Ikyon 
Published: December 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: A Freight Train of Nanotubes for Cargo Transport on the Nanoscale
Authors: Burghard Marko 
Published: December 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Mean Amplitudes of Vibration of Molecules and Ions with Interhalogen Bonds and Related Species
Authors: Baran Enrique J. 
Published: December 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Recent Developments in the Chemistry of Low‐Valent Group 14 Hydrides
Authors: Rivard Eric , Power Philip P. 
Published: December 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Heterocalixaromatics, New Generation Macrocyclic Host Molecules in Supramolecular Chemistry
Authors: Wang Mei‐Xiang 
Published: December 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Benzoheteropines with Fused Pyrrole, Furan and Thiophene Rings
Authors: Tymoshenko D. O. 
Published: December 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Hunter—Killer Peptide (HKP) for Targeted Therapy
Authors: Ellerby H. Michael , Bredesen Dale E. , Fujimura Satoshi , John Varghese 
Published: December 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Supported Liquid‐Phase Systems in Transition Metal Catalysis
Authors: Perosa Alvise , Zinovyev Sergei 
Published: December 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: α,β‐Unsaturated Aldehydes
Authors: Escher I. , Glorius F. 
Published: December 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Arenecarbaldehydes: Synthesis by C—X Bond Formation
Authors: Berkenbusch T. 
Published: December 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Arenecarbaldehydes: Synthesis by C—C Bond Formation
Authors: Oestreich M. 
Published: December 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Arenecarbaldehydes: Synthesis by Hydrolysis of Aldehyde Derivatives
Authors: Ditrich K. 
Published: December 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Group‐Theoretical Approaches in Molecular Magnetism: Metal Clusters
Authors: Tsukerblat Boris 
Published: December 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Heme‐Copper Oxidases and Their Electron Donors in Cyanobacterial Respiratory Electron Transport
Authors: Bernroitner Margit , Zamocky Marcel , Pairer Martin , Furtmueller Paul G. , Peschek Guenter A. , Obinger Christian 
Published: December 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Zinc‐Handling in Cyanobacteria: An Update
Authors: Blindauer Claudia A. 
Published: December 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Thermal‐ and Fast‐Spectrum Molten Salt Reactors for Actinide Burning and Fuel Production
Authors: Forsberg Charles W. 
Published: December 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
NG2 cells are distinct from neurogenic cells in the postnatal mouse subventricular zone
Authors: Komitova Mila , Zhu Xiaoqin , Serwanski David R. , Nishiyama Akiko 
Published: December 2008

AbstractNG2 cells express the chondroitin sulfate proteoglycan NG2 and are a fourth type of glia distinct from astrocytes, oligodendrocytes, and microglia. NG2 cells generate oligodendrocytes but have also been reported to represent neuronal progenitor cells in the postnatal mouse subventricular zone (SVZ). We performed a detailed immunohistochemical analysis of NG2 cells in the mouse SVZ, rostral migratory stream (RMS), and olfactory bulb granule cell layer (OB GCL), which constitute a neurogenic niche in the postnatal forebrain. NG2 cells in the SVZ and RMS expressed the oligodendrocyte precursor cell antigen platelet‐derived growth factor receptor‐α but did not express antigens known to be expressed by neuronogenic cells in the SVZ, such as doublecortin, PSA‐NCAM, beta‐tubulin, Dlx2, or GFAP. More than 99.5% of the proliferating cells in the SVZ were NG2 negative. In the olfactory bulb, NG2 cells were found to generate primarily oligodendrocytes and a small number of astrocytes but not neurons. In the SVZ and RMS, NG2 cells were sparse and made up a much smaller fraction of the cells compared with the surrounding nonneurogenic parenchyma. Parenchymal NG2 cells were often located along the border of the SVZ and RMS. The abundance of NG2 cells increased in the distal parts of the RMS and especially in the OB GCL, where NG2 cell processes were seen in close proximity to many maturing interneurons. Our findings indicate that NG2 cells do not represent neuronal progenitor cells in the postnatal SVZ but are likely to be oligodendrocyte precursor cells. J. Comp. Neurol. 512:702–716, 2009. © 2008 Wiley‐Liss, Inc.
A Single‐Molecule Perspective on the Role of Solvent Hydrogen Bonds in Protein Folding and Chemical Reactions
Authors: Dougan Lorna , Koti Ainavarapu Sri Rama , Genchev Georgi , Lu Hui , Fernandez Julio M. 
Published: December 2008

AbstractWe present an array of force spectroscopy experiments that aim to identify the role of solvent hydrogen bonds in protein folding and chemical reactions at the single‐molecule level. In our experiments we control the strength of hydrogen bonds in the solvent environment by substituting water (H2O) with deuterium oxide (D2O). Using a combination of force protocols, we demonstrate that protein unfolding, protein collapse, protein folding and a chemical reaction are affected in different ways by substituting H2O with D2O. We find that D2O molecules form an integral part of the unfolding transition structure of the immunoglobulin module of human cardiac titin, I27. Strikingly, we find that D2O is a worse solvent than H2O for the protein I27, in direct contrast with the behaviour of simple hydrocarbons. We measure the effect of substituting H2O with D2O on the force dependent rate of reduction of a disulphide bond engineered within a single protein. Altogether, these experiments provide new information on the nature of the underlying interactions in protein folding and chemical reactions and demonstrate the power of single‐molecule techniques to identify the changes induced by a small change in hydrogen bond strength.
Bioinformatics and computational approaches applicable to lipidomics
Authors: Orešič Matej 
Published: December 2008

AbstractLipidomics owes its emergence to technologies developed over the past decade that empowered us with the ability to detect and quantify hundreds of intact lipid molecular species in parallel. One of the biggest current challenges of lipidomics is the elucidation of important pathobiological phenomena from the integration of large amounts of new data becoming available. In this respect, development of lipidomics as a field bears many similarities to the emergence and progress of genomics. Initial excitement over the ability to measure the expression of large numbers of genes in parallel was soon overshadowed by concerns over the ability to reliably analyze and interpret the expression data. This led to active research in the area of bioinformatics, which led to improved statistical methods as well as to new approaches for the analysis of transcriptome data in the pathway context. This review covers recent bioinformatics developments of relevance to analysis and interpretation of analytical lipidomics data, with the focus primarily on practical aspects of lipid bioinformatics.
Association between subjective memory complaints and nursing home placement: a four‐year follow‐up
Authors: Waldorff Frans Boch , Siersma Volkert , Waldemar Gunhild 
Published: December 2008

AbstractObjectiveIn order to evaluate whether elderly persons with subjective memory complaints may be regarded as a group of potentially vulnerable patients who need close follow‐up, we investigated the risk of nursing home placement during a 4‐year follow‐up period.MethodsProspective cohort survey with 4‐year follow‐up in general practice. Cox proportional hazard models were used to examine the influence of risk factors on nursing home placement.ResultsA total 758 non‐nursing home residents aged 65 years and older consulted the General Practitioners in October and November 2002 of whom 50 nursing home placements were observed. Subjective memory complaints were associated with an adjusted Hazard Ratio (HR) of 2.59 for nursing home placement. Other statistical significant covariates were MMSE < 24 (HR = 3.95), Age (HR = 3.92 for 75–84 years and HR = 19.90 for 85 + years) and extreme anxiety/depression (HR = 4.74). The effect of subjective memory complaints is seen to moderate when subjects are older.ConclusionThe data of this study indicated that in an elderly primary care population the presence of subjective memory complaints was a significant independent predictor for nursing home placement together with other known risk factors. Copyright © 2008 John Wiley & Sons, Ltd.
Amygdalae morphometry in late‐life depression
Authors: Tamburo Robert J. , Siegle Greg J. , Stetten George D. , Cois C. Aaron , Butters Meryl A. , Reynolds III Charles F. , Aizenstein Howard J. 
Published: December 2008

AbstractObjectiveThe amygdalae have been a focus of mood disorder research due to their key role in processing emotional information. It has been long known that depressed individuals demonstrate impaired functional performance while engaged in emotional tasks. The structural basis for these functional differences has been investigated via volumetric analysis with mixed findings. In this study, we examined the morphometric basis for these functional changes in late‐life depression (LLD) by analyzing both the size and shape of the amygdalae with the hypothesis that shape differences may be apparent even when overall volume differences are inconsistent.MethodsMagnetic resonance imaging data were acquired from 11 healthy, elderly individuals and 14 depressed, elderly individuals. Amygdalar size was quantified by computing total volume and amygdalar shape was quantified with a shape analysis method that we have developed.ResultsNo significant volumetric differences were found for either amygdala. Nevertheless, localized regions of significant shape variation were detected for the left and right amygdalae. The most significant difference was contraction (LLD subjects as compared to control subjects) in a region typically associated with the basolateral nucleus, which plays a key role in emotion recognition in neurobiologic models of depression.ConclusionsIn this LLD study, we have shown that, despite insignificant amygdalar volumetric findings, variations of amygdalar shape can be detected and localized. With further investigation, morphometric analysis of various brain structures may help elucidate the neurobiology associated with LLD and other mood disorders. Copyright © 2008 John Wiley & Sons, Ltd.
Diabetes mellitus and risk of prostate cancer in the health professionals follow‐up study
Authors: Kasper Jocelyn S. , Liu Yan , Giovannucci Edward 
Published: December 2008

AbstractHistory of diabetes may be associated with decreased prostate cancer (PCa) risk. Published studies have not always accounted for time since diabetes diagnosis or confounding and effect modification by lifestyle factors. The authors investigated the relationship between diabetes and PCa risk in men in the Health Professionals Follow‐Up Study from 1986 to 2004. During that time, 4,511 new PCa cases were identified. Multivariate hazard ratios (HR) were estimated using Cox regression. The HR of PCa comparing men with vs. without diabetes was 0.83 and 95% confidence interval (CI): 0.74, 0.94. PCa risk was not reduced in the first year after diabetes diagnosis (HR: 1.30, CI: 0.97, 1.72), was lower for men diagnosed for 1–6 years (HR: 0.82, CI: 0.66, 1.02), and was even lower for men who had been diagnosed for 6–15 (HR: 0.75, CI: 0.61, 0.93) or >15 years (HR: 0.78, CI: 0.63, 0.96). Reduced PCa risk was stronger in men diagnosed before 1994 (pre‐PSA era) vs. after 1994. The authors also demonstrated that obese and diabetic men had a lower HR for PCa than those who were either not obese and diabetic or obese and non‐diabetic. Results are consistent with the hypothesis that diabetes is associated with reduced PCa risk. Potential biological mechanisms are discussed. © 2008 Wiley‐Liss, Inc.
PDGF‐B induces a homogeneous class of oligodendrogliomas from embryonic neural progenitors
Authors: Appolloni Irene , Calzolari Filippo , Tutucci Evelina , Caviglia Sara , Terrile Marta , Corte Giorgio , Malatesta Paolo 
Published: December 2008

AbstractWe describe the generation of mouse gliomas following the overexpression of PDGF‐B in embryonic neural progenitors. Our histopathological, immunohistochemical and genome‐wide expression analyses revealed a surprising uniformity among PDGF‐B induced tumors, despite they were generated by transducing a highly heterogeneous population of progenitor cells known for their ability to produce all the cell types of the central nervous system. Comparison of our microarray data with published gene expression data sets for many different murine neural cell types revealed a closest correlation between our tumor cells and oligodendrocyte progenitor cells, confirming definitively that PDGF‐B‐induced gliomas are pure oligodendrogliomas. Importantly, we show that this uniformity is likely due to the ability of PDGF‐B overexpression to respecify competent embryonic neural precursors toward the oligodendroglial lineage, providing evidence that the transforming activity of PDGF‐B is influenced by the developmental potential of the targeted cells. Interestingly, we found that PDGF‐B‐induced tumors harbor different proliferating cell populations. However only PDGF‐B‐overexpressing cells are tumorigenic, indicating that paracrine signaling from the tumor is unable to transform bystander cells. © 2008 Wiley‐Liss, Inc.