bluuebunny/crossref_metadata_2025_split huggingface dataset:
Theoretical assessment of discharge effects on the decomposition tendency of C6F12O over metallic surfaces
Authors: Cui Zhaolun , Hao Yanpeng , Tian Shuangshuang , Zhang Xiaoxing , Zheng Yashuang 
Published: March 2024

AbstractC6F12O is proposed to be one potential eco‐friendly insulation gas to replace SF6. However, the assessment of its decomposition properties and the compatibility with metal electrodes in discharge faults is still challenging, which greatly hinders the development of its insulation and arc‐extinction applications. Herein, a theoretical method is proposed to reasonably address the discharge effects on C6F12O decomposition over typical Cu and Al electrodes at atomic scale. The results show that both the external electric field and the excess electrons could affect the activation of C6F12O by changing the electron acceptance of C6F12O and the orbital hybridisation during the surface bonding. On metal surfaces, the C‐F single bond in adsorbed C6F12O is the weakest position to decompose, and its cleavage could be promoted by the discharge effects. After the C‐F breaking, the C‐C cleavage remains unfavourable on Cu (111), but it is significantly promoted on Al (111), indicating a higher corrosion risk on the Al surface via continuous C6F12O decompositions. The proposed method as a valid supplement to the experiment reveals the discharge effects and the decomposition tendency of C6F12O on metal electrodes in discharge faults, which broadens the means for insulation gas evaluation.
Time transfer via single‐record TDoA measurements of GNSS satellites using direct cross‐correlation and relative pilot code phases
Authors: Busley Erik , Žuntar Timotej , Borgmann Jörg , Krist Michael 
Published: March 2024

AbstractRadar systems are evolving towards distributed receiver networks. As individual stations might be separated too far to install a cable link, novel methods are required to synchronise individual data records in the time domain. State‐of‐the‐art GNSS receivers disciplining a highly stable oscillator are able to output a timing signal with several nanosecond accuracy solely using non‐proprietary signals. However, they typically require a stable environment and become a major cost factor for receiver networks with a high number of nodes. A method is presented to passively synchronise data records via GNSS raw signals in a single record requiring only a GNSS antenna, an analogue‐to‐digital converter and computation hardware. The clock bias is estimated via the common view method with either full raw signal correlation or software‐based code correlation of individual signals from the GPS, Galileo and BeiDou constellation with sub‐nanosecond precision.
Patient access – Zugang zu Innovationen in der Onkologie
Authors: Berger-Thürmel Karin , Westphalen C. Benedikt , von Bergwelt-Baildon Michael 
Published: March 2024

WAS IST NEU?
Innovative onkologische Diagnostik und Therapien Im Vergleich zu anderen europäischen Ländern steht in Deutschland eine Vielzahl an innovativen Therapieoptionen für die Behandlung von Patienten mit Krebs zur Verfügung. Aktuell besteht die Herausforderung in der Versorgung vor allem darin, allen Patienten, die einen Nutzen von innovativen Therapien erfahren könnten, unabhängig vom Wohnort und Behandlungsumfeld diese Optionen zum richtigen Zeitpunkt anzubieten zu können.
Zugang über klinische Studien, molekulare Tumorboards Klinische Studien sind häufig die erste Möglichkeit für einen kontrollierten Zugang zu onkologischer Innovation. Der Abbau von bürokratischen Prozessen sowie die Steigerung der Transparenz über aktuell rekrutierende Studien ist zwingend notwendig, um mehr Patienten den frühen Zugang über Sektorengrenzen hinweg zu ermöglichen. Auch das Konzept dezentraler klinischer Studien und (virtueller) molekularer Tumorboards ist geeignet, um mehr Patienten einen potenziellen Studieneinschluss zu ermöglichen.
Kosten innovativer onkologischer Therapie Der bestmögliche Einsatz einer wachsenden Zahl innovativer und kostenintensiver Diagnostik- und Therapiemöglichkeiten für unterschiedlichste, patientenindividuelle Situationen erfordert den niederschwelligen transsektoralen Austausch, d. h. Kommunikation zwischen (zertifizierten) onkologischen Kompetenzzentren und Ärzten in der Breite der medizinischen Versorgung, die im Versorgungsalltag gleichzeitig die Großzahl der deutschen Krebspatienten behandeln und die gesamte Bandbreite der immer komplexeren onkologischen Therapielandschaft abdecken sollen.
Innovative Therapien: unterschiedlicher Zugang in den Regionen Die überfällige Implementierung von digitalen Möglichkeiten für die sektorenübergreifende Zusammenarbeit ist unbedingte Voraussetzung, um Patienten mit räumlich größerer Entfernung zu einem Kompetenz- bzw. Studienzentrum Zugang zu Innovation zu ermöglichen, die am Wohn- bzw. Behandlungsort nicht vorgehalten wird.
Neue Versorgungsformen: optimierter Zugang zu innovativer Versorgung Zur Entwicklung und Erprobung neuer Versorgungsformen ist die Beteiligung aller am Versorgungsprozess beteiligten Verantwortlichen notwendig, um strukturelle Voraussetzungen gemeinschaftlich zu verbessern, nachhaltige Anreize zu schaffen und entsprechend notwendige Kapazitäten vorzuhalten. Grundlage hierfür ist eine fortlaufende, konzertierte Bereitstellung von Evidenz zur Versorgungssituation, z. B. im Kontext der gesetzlichen Krebsregistrierung und klinischer Register an onkologischen Zentren.
Use of Vonicog Alpha and Acquired von Willebrand Syndrome, a New Approach: A Case Report
Authors: Blandinières Adeline , Combe Sophie , Chanson Noémie , Lambotte Olivier , Lavenu-Bombled Cécile 
Published: March 2024

AbstractTherapeutic management of acquired von Willebrand syndrome (AVWS) can be challenging, particularly in cases of AVWS associated with monoclonal IgM such as Waldenström macroglobulinemia (WM) where several therapeutic options may be ineffective. Here, we describe the case of an 88-year-old patient who developed AVWS during follow-up for WM. The presence of a severe bleeding symptomatology not controlled by several therapies (plasma-derived von Willebrand factor, plasmapheresis) led us to introduce a supplementation with recombinant von Willebrand factor, vonicog α (Veyvondi, Takeda, Japan), starting at a dose of 50 IU/kg/d. This supplementation allowed clinical (no further bleeding) and biological (hemoglobin level, von Willebrand factor parameters) improvements. Because of the persistence of bleeding risk factors, the treatment was maintained at a prophylactic dose (20 UI/kg three times a week), without recurrence of bleeding events for a period of 9 months.
Digitale Konzepte für die Versorgung von Neugeborenen mit
kraniofazialen Anomalien
Authors: Hülsbeck Albert , Northoff Lisa-Marie , Kahl-Nieke Bärbel 
Published: March 2024

ZusammenfassungDie Behandlung von Neugeborenen mit kraniofazialen Fehlbildungen wie
Lippen-Kiefer- und/oder Gaumenspalten stellt Behandler:innen vor besondere
Herausforderungen. Oft ist die interdisziplinäre Zusammenarbeit eines Teams aus
Pädiater:innen, Kieferorthopäd:innen und Mund-Kiefer-Gesichtschirurg:innen
erforderlich. Eine Therapie mit Trink- und/oder Stimulationsplatten kann die
Nahrungsaufnahme verbessern und den orofazialen Muskeltonus stärken. Die
Behandlung von Patient:innen mit Lippen-Kiefer-Gaumenspalten mithilfe
konventionell hergestellter Trinkplatten sowie die Behandlung von Patient:innen
mit verringertem orofazialen Muskeltonus im Rahmen einer Therapie mit
Stimulationsplatten sind etablierte und vielerorts angewandte Verfahren. Jedoch
können bei der konventionellen Herstellung dieser Plattenapparaturen
schwerwiegende Komplikationen wie das Verschlucken von Abformmaterial sowie die
Verlegung der Atemwege durch Aspiration auftreten. Durch einen innovativen,
vollständig digitalen Workflow mittels Computer-Aided-Design und -Manufacturing
der Apparaturen im 3D-Drucker werden Risiken minimiert und Zeit sowie Kosten
gespart. In diesem Artikel soll anhand zweier Kasuistiken der digitale Workflow
der Behandlung von Neugeborenen mit 3D-CAD/CAM Trink- und Stimulationsplatten
erläutert werden.
Visible-Light-Catalyzed Regioselective Arylcarboxylation of Allenes with CO2
Authors: Zhang Zhenqiang , Zhan Zhuangping , Zhang Xianming 
Published: March 2024

AbstractA visible-light-catalyzed arylcarboxylation of allenes with CO2 was developed using [Ir(ppy)2(dtbbpy)]PF6 (ppy = 2-phenylpyridine; dtbbpy = 4,4′-di-tert-butyl-2,2′-bipyridine) as a photocatalyst to synthesis β-aryl β,γ-unsaturated carboxylic acids. This multicomponent protocol proceeds in an atom-economical way with exclusive regioselectivity. Preliminary mechanistic experiments suggested that allylic carbanion species are the key intermediates.
Anal and Perianal Masses: The Common, the Uncommon, and the Rare
Authors: Augustine Antony , Issac Rijo , Lakhani Aisha , Kanamathareddy Harsha Veena , John Reetu , Simon Betty , Masih Dipti , Eapen Anu , Chandramohan Anuradha 
Published: March 2024

AbstractA variety of tumors involve the anal canal because the anal canal forms the transition between the digestive system and the skin, and this anatomical region is made of a variety of different cells and tissues. Magnetic resonance imaging (MRI) is the modality of choice for diagnosis and local staging of the anal canal and perianal neoplasms. In this pictorial review, we demonstrate the MRI anatomy of the anal canal and perianal region and display the imaging spectrum of tumors in the region along with an overview of its management. Imaging appearances of many tumorlike lesions that can cause diagnostic dilemmas are also demonstrated with pointers to differentiate between them.
Endothelial LAT1 (SLC7A5) Mediates S-Nitrosothiol Import and Modulates Respiratory Sequelae of Red Blood Cell Transfusion In Vivo
Authors: Zhu Hongmei , Auten Richard L. , Whorton Augustus Richard , Mason Stanley Nicholas , Bock Cheryl B. , Kucera Gary T. , Kelleher Zachary T. , Vose Aaron T. , McMahon Tim J. 
Published: March 2024

Background Increased adhesivity of red blood cells (RBCs) to endothelial cells (ECs) may contribute to organ dysfunction in malaria, sickle cell disease, and diabetes. RBCs normally export nitric oxide (NO)-derived vascular signals, facilitating blood flow. S-nitrosothiols (SNOs) are thiol adducts formed in RBCs from precursor NO upon the oxygenation-linked allosteric transition in hemoglobin. RBCs export these vasoregulatory SNOs on demand, thereby regulating regional blood flow and preventing RBC–EC adhesion, and the large (system L) neutral amino acid transporter 1 (LAT1; SLC7A5) appears to mediate SNO export by RBCs.
Methods To determine the role of LAT1-mediated SNO import by ECs generally and of LAT1-mediated SNO import by ECs in RBC SNO-dependent modulation of RBC sequestration and blood oxygenation in vivo, we engineered LAT1fl/fl; Cdh5-Cre+ mice, in which the putative SNO transporter LAT1 can be inducibly depleted (knocked down, KD) specifically in ECs (“LAT1ECKD”).
Results We show that LAT1 in mouse lung ECs mediates cellular SNO uptake. ECs from LAT1ECKD mice (tamoxifen-induced LAT1fl/fl; Cdh5-Cre+) import SNOs poorly ex vivo compared with ECs from wild-type (tamoxifen-treated LAT1fl/fl; Cdh5-Cre−) mice. In vivo, endothelial depletion of LAT1 increased RBC sequestration in the lung and decreased blood oxygenation after RBC transfusion.
Conclusion This is the first study showing a role for SNO transport by LAT1 in ECs in a genetic mouse model. We provide the first direct evidence for the coordination of RBC SNO export with EC SNO import via LAT1. SNO flux via LAT1 modulates RBC–EC sequestration in lungs after transfusion, and its disruption impairs blood oxygenation by the lung.
A Case Report of the First CEA Transplant in an HIV-Positive Burn Patient in South Africa Using a Novel Composite Culture Technique
Authors: Kleintjes Wayne George , Prinsloo Tarryn Kay 
Published: March 2024

AbstractResource-limited burn centers are usually devoid of cultured epithelial autografts (CEA) owing largely to prohibitive costs. A modified CEA technique at our burn center incorporated cost-effective, routinely-used dressings with favorable outcomes. One unknown concern was the immunosuppressive effect that extensive burns and potentially human immunodeficiency virus (HIV) infection may have on graft take. This case study reports on the graft take outcomes of the first CEA transplanted in an HIV-positive patient with extensive burns in South Africa, using this technique. Graft take was determined after 21 days at 80% and a long-term follow-up of 8 years indicated good pigmentation return and skin pliability. Delayed diagnosis of pyoderma gangrenosum caused partial graft loss; however, successful regrafting occurred after pyoderma gangrenosum treatment and eradication. The case was considered clinically successful. HIV may not directly affect graft take, but may result in immunosuppressive conditions that delay graft take success.
Percutaneous Biliary Interventions in Pediatric Patients
Authors: Vogt Katharina , Hammer Simone , Grözinger Gerd , Knott Emily A. , Uller Wibke 
Published: March 2024

AbstractPercutaneous biliary interventions have become standard for a variety of indications in pediatric patients. They offer a minimally invasive approach to managing biliary pathologies often associated with liver transplantation and hepatobiliary surgery. Interventions include the insertion of drainage catheters for bilomas, percutaneous transhepatic cholangiography for diagnostic purposes, and percutaneous transhepatic biliary drainage for the treatment of biliary leaks and cholestasis. Sonography, computed tomography, and fluoroscopy are used to guide the procedures. This review aims to demonstrate the indications and technical aspects of percutaneous biliary interventions in pediatric patients with a special focus on radiation protection.
Deep Neck Lifting
Authors: Wever Capi C. 
Published: March 2024

AbstractCreating tight and durable profile neck results has perhaps become the principal objective of many surgeons. On social media such results are quickly recognized by colleagues and potential clients alike, much more so than “en-face” results. Yet individual patient characteristics play an essential role in determining if such results are technically possible and also dictate which techniques are required to achieve it. In many patients, these techniques involve manipulation of the deeper neck structures and are oriented more laterally than the direct submental region. Each surgeon needs to decide which technique feels proportionate in terms of an individualized risk–benefit analysis.
The contact origin(s) of ‘hand’ and ‘foot’ > ‘limb’ in
Antioquian Spanish
Authors: Raynor Eliot 
Published: March 2024

Abstract
This study examines the semantic extension of
mano ‘hand’ and pie ‘foot’ to
their contemporary senses of ‘upper limb’ and ‘lower limb’ in
Spanish varieties of Antioquia, Colombia. This dialectally
idiosyncratic pattern, hitherto unexplained in the literature, is
accounted for here as the combined outcome of adult acquisition
among various groups. First, Chocoan languages predominating in the
region throughout the early colonial period show a congruent pattern
in the lexemes for ‘upper limb’ (e.g., Embera Chamí
húa) and ‘lower limb’ (e.g., Embera Catío
hẽ́ɾṹ), and their speakers plausibly initiated
the change via L1 transfer. Chroniclers’ accounts also reveal that
Antioquia’s earliest Europeans relied heavily upon enslaved
African(-descendants), and records of ships carrying enslaved
peoples to the nearby port cities demonstrate that much of the
African-born population in 16th-century Antioquia spoke languages
with congruent patterns also (e.g., Kikongo kóoko
‘upper limb’ and kúulu ‘lower limb’). It is
proposed that adult Spanish learners with these L1s reinforced the
innovative variant.
Towards an acquisitionally informed historical
sociolinguistics
Authors: Sanz-Sánchez Israel 
Published: March 2024

Abstract
This conclusion chapter offers an overview of
some of the main themes developed throughout the volume and
highlights several important theoretical and methodological
implications for the development of new acquisitionally informed
research agendas in historical sociolinguistics. The use of
acquisition theory and corpora as sources of information to
interpret the sociohistorical and sociolinguistic archive is
complicated by several methodological and analytical hurdles –
nevertheless, it is argued here that acquisitional analogues between
past and present and a knowledge of how various groups of learners
process different forms of variation can do much to propel the study
of language variation and change in historical situations. In
addition, new technological developments and sources of data can
furnish researchers additional information about how individual
acquisitional trajectories may have contributed to the linguistic
patterns attested in the archival record. Lastly, an acquisitionally
informed perspective can also be a step to address structural
inequalities in linguistic description and in the construction of
knowledge in our field.
The unfinished double glosses in Durham Cathedral Library, MS A.iv.19
Authors: Langmuir Christopher 
Published: March 2024

Abstract
Incomplete multiple glosses are a prominent feature of Aldred’s glossing practice in the Lindisfarne Gospels
(Cotton MS Nero D IV). In his later gloss, that to Durham Cathedral Library, MS A.iv.19, incomplete double glosses are
predominant. Their raison d´être is unclear. This paper addresses the range of functions represented
by vel (‘or’) in Durham Cathedral Library, MS A.iv.19. It is argued that the appended
vel of incomplete glosses may carry a vel potius (‘or rather’) value thereby
alerting readers to the provisional character of the gloss. Inspection of the manuscript reveals that in many
instances insufficient space has been allowed for any second gloss. Incomplete glosses must also be considered in the
context of how the same lemmata are glossed elsewhere in the manuscript.
Investigating the dynamics of the lexicon
Authors: Landmann Julia 
Published: March 2024

Abstract
This chapter focuses on the lexical influence of Yiddish on English throughout its history. The findings
rely on an analysis of the linguistic evidence in electronic dictionaries and corpora. Specific value will be accorded
to the use of Yiddish borrowings in informal language. Yiddish has provided English with a number of terms relating to
various semantic domains, ranging from gastronomy, faith and religion, to people and everyday life. An important
objective is to provide an overview of the domains influenced by Yiddish over time. Particular attention will be given
to socio-cultural and historical reasons that might explain the introduction and spread of Yiddish borrowings into
different domains over the centuries, contributing to variation in the English lexicon.
A manipulative technique in a congressional debate
Authors: Rudanko Juhani , Rickman Paul 
Published: March 2024

Abstract
This article examines a debate in the United States House of Representatives in 1789 and presents a case study of ad socordiam, which is shown to be an informal fallacy in the language of politics. This fallacy is based on inferences about covert intentions of speakers, depending in part on the level of the hearer’s epistemic vigilance. The study shows how an inference about a speaker’s intention can be substantiated on the basis of evidence even in the case of a historical debate. The present study advocates a view of pragmatics and discourse analysis that regards inferences about covert intentions as a legitimate object of investigation to provide a fuller picture of political debates involving deep disagreements and manipulation.
“No criticism or remarks & pray burn it as fast as you read it”
Authors: Oudesluijs Tino 
Published: March 2024

Abstract
Building on what has been written about copy letters and copying practices in Late Modern English correspondence, this paper explores the copying behaviour of a highly cultured and well-connected woman in eighteenth-century British polite society, Mary Hamilton (1756–1816), by closely scrutinising a selection of her writings containing material copied from various other letters. Close attention is paid to what linguistic features were changed in the copying process, which is contextualised and subsequently discussed in the appropriate socio-historical context. The case studies reveal that various linguistic elements were changed in the copying process, part of which can be attributed to changes in addressee, Hamilton’s expectations of who else might read her writings, and how her letters would have been delivered.
Raising awareness of stroke, stroke survivor-perspectives, and stroke–carer research
Authors: Kambanaros Maria 
Published: March 2024

Abstract
The aim of this chapter is to propose a research agenda that will promote awareness of stroke warning signs and risk for stroke in culturally and linguistically diverse (CALD) communities. The targeted community in this case, is the Greek immigrant community in Australia. The research agenda also advocates a better understanding of CALD stroke survivors and carers needs to enable capacity-building to encourage wellbeing by supporting unmet needs. This will have a positive impact on health, care and psychosocial outcomes for people living with stroke deficits from CALD backgrounds and their carers and families who support them in everyday life.
Subjecthood transparency
Authors: O’Conaill Donnchadh 
Published: March 2024

Abstract
In recent work Philip Goff has defended the thesis of subjecthood transparency: someone possessing the concept ‘subjecthood’ is thereby in a position to know, a priori, what it is for an entity to be a subject of experiences. Kevin Morris has criticized a specific argument that Goff provides for subjecthood transparency. I will argue that Morris’s criticism of Goff’s argument does not succeed. I will then present an alternative criticism of Goff’s argument, one that also applies to the thesis of subjecthood transparency itself.
To reason or not to reason: arbitral awards—the conflict between conciseness and the duty to provide reasons under national laws and international rules
Authors: Zamir Noam , Kaplan Neil 
Published: March 2024

Abstract
The duty to give reasons in arbitral awards has a mixed history. While it can be traced back to the second part of the 20th century in England, it has been part of accepted practice in civil law countries for a long period. It has become the norm in international arbitration, both in commercial disputes and in investment disputes. While the duty to give reasons is, in general, positive, this article suggests that many international awards tend to be too long. This prolongs the arbitration proceedings and increases costs—both in terms of the arbitrators’ fees and the costs that the parties to dispute must bear while waiting for the award to be issued. To tackle this problem, the article examines the required scope of reasoning in international awards; it then discusses why many international awards tend to be too long. Finally, it suggests ways in which awards can and should be shorter.