bluuebunny/crossref_metadata_2025_split huggingface dataset:
Primary nasal tuberculosis masquerading as a malignant tumour
Authors: Sim David W. , Crowther John A. 
Published: November 2007

AbstractPrimary nasal tuberculosis is rare. We report a case of primary nasal tuberculosis in an elderly lady who presented with symptoms and signs suggestive of a nasal fossa tumour. Histological examination of the lesion revealed the diagnosis. Treatment was with standard anti-tuberculous chemotherapy. The implications of primary nasal tuberculosis are discussed.
Craniofacial resection for extensive paranasal sinus aspergilloma
Authors: Quiney R. E. , Rogers M. J. C. , Davidson R. N. , Cheesman A. D. 
Published: November 2007

AbstractCraniofacial resection techniques were developed to allow complete monobloc removal of malignant tumours of the ethmoid region. Such a surgical approach may also occasionally be useful in certain non-malignant conditions. Extensive ‘destructive’ aspergillosis of the paranasal sinuses has a high mortality once the anterior cranial fossa dura is reached. Craniofacial surgery provides excellent access to excise such large infective ‘tumours’.
Sqamous carcinoma arising within a Warthin's tumour of the parotid gland
Authors: Morrison G. A. J. , Shaw H. J. 
Published: November 2007

AbstractThe rare case of a patient who developed a squamous carcinoma within a Warthin's tumour of the parotid gland (adenolymphoma or papillary cystadenoma lymphomatosum) is described. We have found ten previously reported cases, only four of which have shown squamous carcinomatos change.
Ototoxicity of ear drops in patients suffering from chronic otitis media
Authors: Podoshin L. , Fradis M. , David J. Ben 
Published: November 2007

AbstractThe sensorineural hearing loss in 150 patients with chronic otitis media who were treated in the Haifa Medical Center (Rothschild) during a ten year period was studied. There were 124 patients treated with a mixture containing neomycin, polymyxin B and dexamethasone and a control group of 26 patients with dexamethasone only.All patients were followed up for a period of 1–2 years. Patients with hearing loss due to factors such as previous ear surgery, family history, exposure to noise etc., have been excluded.The conclusions reached were that there is a relationship between the period of disease and the sensorineural hearing loss and that the local treatment with a mixture containing neomycin + polymyxin B appears to contribute to the worsening of the sensorineural hearing loss in patients with chronic otitis media.Our numbers are small and further studies must be done, but the fact that currently used ear drops may produce a sensorineural hearing loss should not be ignored.
Sensorineural hearing loss in chronic otitis media
Authors: Cusimano F. , Cocita V. C. , D'Amico A. 
Published: November 2007

AbstractA statistical study was done on the sensorineural component in hearing loss, using 595 patients suffering from Chronic Otitis Media (COM); of these, 195 with monolateral COM were taken into consideration. They presented criteria of valuation which excluded other possible causes of sensorineural hearing loss, such as exposure to acoustic trauma, ototoxic drugs, cardiovascular disease, past head injury and hereditary causes. The contralateral (healthy) ear served as a control. We determined the average sensorineural component in the hearing losses in relation to the age of onset and duration of the disease, examining it in relation to other eventual aural complications such as cholesteatoma.On the basis of the data obtained, we believe that the sensorineural component in hearing loss does not change with respect to the age of onset of COM, but the duration of COM does exert a significant influence.
Hearing threshold in patients with diabetes mellitus
Authors: Kurien M. , Thomas K. , Bhanu T. S. 
Published: November 2007

AbstractHearing threshold of 30 diabetic patients and 30 healthy controls attending the medical outpatient department were determined using pure tone audiometry (Arphi Digital 900). All subjects were less than 50 years old. Subjects with otological and other metabolic diseases were excluded from the study. The patients were categorized into groups according to age, duration of disease, complications and control of diabetes. These observations were compared with those from the control subjects using appropriate statistical methods.It was found that diabetics had a poorer hearing threshold than the non-diabetics; all age groups with diabetes showed a significant high frequency hearing loss, as compared to the control population; poorly controlled and complicated diabetics have significant, high frequency hearing loss as compared to those who were well controlled and uncomplicated; there was no relationship between duration of the diabetes and the level of hearing loss.
CT air meatography: review of side effects in 60 patients
Authors: Smith I. M. , Turnbull L. W. , Sellar R. J. , Murray J. A. M. 
Published: November 2007

AbstractSixty patients investigated for a suspected acoustic neuroma were questioned on the side effects of CT air meatography, a minimum of three months following the procedure. Twelve per cent of patients found the procedure itself so painful that a repeat examination would only be contemplated under general anaesthesia. Only 20 per cent of patients were asymptomatic after the procedure while 28 per cent of patients required bed rest for 24 hours or more (average 4.4±2.8 days). Sixty-two per cent of patients took three days or longer to return to normal health.The duration and frequency of side effects is greater than previously reported, and emphasizes the need for full investigation of these patients prior to CT air meatography.
Culture of Rhinosporidium seeberi: Preliminary report
Authors: Krishnamoorthy S. , Sreedharan V. P. , Koshy P. , Kumar S. , Anilakumari C. K. 
Published: November 2007

AbstractEvery year 400 to 450 cases of Rhinosporidium are reported from Trivandrum Medical College. Twenty five swabs were collected from patients suffering from Rhinosporidiosis and cultured in standard media. Positive results were obtained in 23 cases. The conidia produced from the colony were compared with the structures obtained from the patient material. Light microscopy using histopathological techniques were used. The consistant appearance of the organism in patient material, the repeatability of growth in subcultures and the negative growth in controls indicated that the organism grown in cultures is the causative agent of the disease. The effect of parameters like pH, temperatures, etc, were also studied.
Cricothyroid muscle paralysis: its recognition and diagnosis
Authors: Bevan K. , Griffiths M. V. , Morgan M. H. 
Published: November 2007

AbstractCricothyroid muscle paralysis is often missed as the symptoms are not dramatic and the laryngeal observations, on conventional indirect mirror examination, are inconclusive. The anatomy and physiology of the superior laryngeal nerve (SLN) and cricothyroid muscle are described. Three case reports are presented to illustrate our diagnostic techniques. Videofibrolaryngoscopy and electromyography are found to be invaluable tools for the diagnosis of this condition. The importance in diagnosing this entity is discussed.
Serum enzymes in head and neck cancer. IV: 5-nucleotidase
Authors: Lal H. , Kumar L. , Kohli G. S. , Sharma A. , Goel H. 
Published: November 2007

AbstractSerum 5-nucleotidase levels have been estimated in a group of 50 patients with head and neck cancer. The mean value was significantly higher in patients compared to the controls. In patients with non-malignant growths, the activity was comparable with the controls. The increase was higher in patients with proliferative lesions than those with ulcerative growths. Enzyme activity was found to be increased with the advancement in the stage of cancer. The rise was comparatively higher in patients with cervical metastasis. After radiotherapy, a gradual and significant reduction of serum 5-nucleotidase activity was observed.
Asthma therapy and a tracheostomy
Authors: O'Callaghan C. , Dryden S. , Cert D. N. , Gibbin K. 
Published: November 2007

AbstractA spacer device was modified to deliver aerosols of beclomethasone diproprionate, ipratropium and bromide sal-butamol, to an asthmatic child with a tracheostomy, where symptoms were poorly controlled with nebulized therapy. This resulted in a marked improvement in symptoms and a dramatic reduction in the time spent administering drugs.
Role of irradiation in the suppression of parotid secretions
Authors: Robinson A. C. R. , Khoury G. G. , Robinson P. M. 
Published: November 2007

AbstractSuppression of salivary flow is of value in the management of salivary fistulae and sialectasia. It may also be beneficial in mentally defective patients and those with neurological palsies lacking control of their salivation. Nine patients were treated by irradiation to the parotid gland to control salivary flow; eight had complete resolution of symptoms and one had partial relief. Irradiation was effective as primary treatment and after failed surgery and/or drug treatment. Low doses were effective and there were no significant acute or long-term side effects. Its use avoids long-term medication and their potential side effects and may reduce the need for surgery.
Adenoid cystic carcinoma of the salivary glands: Clinicopathological survey of 51 patients
Authors: Koka V. N. , Tiwari R. M. , van der Waal I. , Snow G. B. , Nauta J. , Karim A. B. M. F. , Tierie A. H. 
Published: November 2007

AbstractA clinicopathological study of 51 cases of adenoid cystic carcinoma in the head and neck region seen over a period of 20 years is presented. The correlation between various histological features and their impact on the results is attempted. Longterm results with respect to loco-regional recurrences, distant metastases and survival with various modalities of therapy are presented. Although this is a small series, radical surgery in keeping with the aim of avoiding undue mutilation, thus preserving the quality of life, followed by a full course of radiotherapy has been the mainstay of treatment and the results here presented justify this approach.
Spontaneous external carotid artery occlusion
Authors: Dixon J. A. 
Published: November 2007

AbstractThe case of a 64-year-old man who presented with severe left sided facial pain and cyanosis of the left ear, preauricular region and tongue is described. Digital subtraction angiography confirmed complete occlusion of the left external carotid artery. The patient was anticoagulated and his symptoms resolved over the following month, presumably due to improvement of collateral blood supply to the ischaemic areas. The literature on the clinical manifestations of external carotid ischaemia is reviewed and the relationship between facial pain, internal and external carotid atherosclerosis is emphasised.
Thrombosis of the internal carotid artery due to soft palate injury
Authors: Mains Brian , Nagle Michael 
Published: November 2007

AbstractThrombosis of the internal carotid artery is a rare complication of soft palate injury, only 16 cases having been previously documented. We present the case of a 51/2 year-old-boy who sustained an apparently trival laceration to the right aspect of the soft palate. However, 48 hours after injury, a right cerebral infarct occurred with subsequent left hemiparesis. On supportive and rehabilitative management he made a good recovery over a period of one year.
Temporal bone laboratory training for stapedectomy
Authors: Murrant N. J. , Gatland D. J. 
Published: November 2007

AbstractPractice in the Temporal Bone laboratory is a fundamental part of Otological training. Performing a stapedectomy on a normal temporal bone is handicapped by the mobility of the footplate. We describe a simple method of producing stapes footplate fixation in a normal temporal bone so that the operative conditions found in otosclerosis are more closely simulated.
Hearing aids—a case for review
Authors: Harries M. L. L. , Baguley D. M. , Moffat D. A. 
Published: November 2007

AbstractAn analysis of a series of 100 patients aged 60 years or over, referred by their General Practitioner to the Department of Otolaryngology, Addenbrooke's Hospital, specifically for the provision of a hearing aid, is presented.Forty-six per cent of patients failed to satisfy the criteria suggested by the Technicians, Therapists and Scientists in Audiology as a screening for treatable pathology.This study has shown that the existing referral pattern of general practitioner to consultant otolaryngologist for the provision of a hearing aid reflects the highest quality of care for the patient.Direct referral or open access of patients for hearing aid fitting may risk failure to diagnose early and treatable conditions.
Antroscopy in maxillary sinus disease associated with nasal polyposis
Authors: Gilbert J. G. 
Published: November 2007

AbstractAlthough the association of maxillary sinusitis with nasal polyps is widely recognized little has been written on its precise incidence and degree. Antroscopy of 70 antra with ipsilateral polyps showed a high incidence of mucosal abnormalities, retained secretions and ostial narrowing. Comparison of these findings with pre-operative X-rays showed the latter were unreliable in detecting retained antral fluid. It is concluded that in nasal polyposis the antra warrant careful assessment and that antroscopy is a highly satisfactory method for this purpose.
Angiosarcoma of the nasal cavity and maxillary antrum
Authors: Kurien M. , Nair S. , Thomas S. 
Published: November 2007

AbstractAngiosarcoma (malignant haemangioendothelioma) of the nasal cavity and paranasal sinuses is extremely rare. Only a few cases have been reported in literature. A case of angiosarcoma of the nasal cavity and maxillary antrum in a 38-year-old male patient is reported. He was treated with pre-operative external radiotherapy followed by wide excision of the tumour. He currently remains free of the disease 10 months after diagnosis (and seven months after completing therapy).
Laryngotracheal resection for post scleromatous laryngeal stenosis
Authors: Rifai Mohamed 
Published: November 2007

AbstractScleroma is an endemic disease in Egypt, which frequently results in subglottic laryngeal stenosis. Six patients suffering from laryngoscleroma are represented. They all underwent laryngotracheal resection of the stenosed segment, followed by direct anastomosis. The results were satisfactory in four of the patients. Surgery was abandoned in one patient who was believed to suffer from perichondritis following previous surgery. Restenosis occurred in a 14-year-old girl two weeks after surgery. This was attributed to recurrence, possibly due to residual activity of the disease which was missed before surgery.
Parapharyngeal mass presenting with sleep apnoea
Authors: Veitch D. , Rogers M. , Blanshard J. 
Published: November 2007

AbstractA 60-year-old man presented with a history of progressive sleep disturbance due to an intraoral parapharyngeal salivary gland tumour.The sleep study performed post-operatively showed rapid resolution of nocturnal hypoxic episodes. This appears to be the first recorded case of a parapharyngeal mass causing sleep apnoea and we review the current literature on obstructive sleep apnoea.
Cystic hygroma presenting in adulthood
Authors: Baer S. , Davis J. 
Published: November 2007

AbstractWe report a typical case of cystic hygroma presenting in an elderly female patient. A review of the literature on this condition reveals that although rare in adults, it should form part of the differential diagnosis of a cystic swelling in the neck in this group of patients as well as in the more commonly observed juvenile population. The embryology and pathogenesis of lymphangiomata are discussed as well as the recommended management of a cystic hygroma in an older patient.
Some observations on submucous diathermy
Authors: Woodhead C. J. , Wickham M. H. , Smelt G. J. C. , Macdonald A. W. 
Published: November 2007

AbstractSubmucosal diathermy (SMD) of the inferior turbinates is widely used, although its effect histologically has not been well shown. We attempted to demonstrate the acute histological changes of SMD by performing it immediately prior to inferior turbinectomy. The results found help to explain the unpredictability of producing a clinical response.
Incidence of abnormality in routine ‘vocal cord checks’
Authors: Curley J. W. A. , Timms M. S. 
Published: November 2007

AbstractWhere elective surgery carries a risk of damage to the recurrent laryngeal nerve, pre-operative examination of the larynx is routine. The incidence of positive findings at such examination has been determined by retrospective review of 1,947 clinic records. Only 31 vocal cord palsies were found. The possible causes and relevance of such findings are discussed.
Anterior neck lipoma masquerading as an external laryngocoele
Authors: Ramakantan R. , Shah P. 
Published: November 2007

AbstractLipomas of the anterior neck are rare lesions with about 40 cases reported so far in the world literature. Though lipomas are known to change shape depending upon adjacent compressive forces, our case is unique in that the change in shape clinically mimicked an external laryngocoele. A possible explanation for the unusual behaviour of this lipoma is offered.
Effect of acoustic overstimulation on the glycocalyx and the ciliary interconnections in the organ of Corti: High resolution scanning electron microscopic investigation
Authors: Takumida M. , Fredelius L. , Bagger-Sjöbäck D. , Harada Y. , Wersäll J. 
Published: November 2007

AbstractChanges in ciliary interconnections in the organ of Corti are described after acoustic overstimulation using a special high resolution scanning electron microscope and tannic acid-osmium staining technique, giving an almost three dimensional view. Guinea pigs were exposed to a 3.85 kHz pure tone at an intensity of 120 dB for 22.5 minutes. The first detectable change was a disarrangement of the cilia with a loosening of the interconnections. The ciliary plasma membrane presented with an abnormally smooth appearance. The tip links connecting the tips of the stereocilia to their taller neighbours were also affected showing elongation or even disappearance. The fine granules which cover the tips of the tallest stereocilia of the outer hair cells were decreased. These findings suggest that acoustic overstimulation may affect the carbohydrate metabolism exceding to degeneration of ciliary interconnections resulting in a disarrangement and detachment of cilia. The tip links, which may participate in sensory cell transduction, seem also to be affected by acoustic overstimulation.
Wegener's granulomatosis, subglottic stenosis and antineutrophil cytoplasm antibodies.
Authors: Hoare T. J. , Jayne D. , Evans P. Rhys , Croft C. B. , Howard D. J. 
Published: November 2007

AbstractWegener's granulomatosis is difficult to diagnose, especially when the presentation is unusual, restricted to an isolated region. We report four cases of recurrent subglottic stenosis posing difficulty in diagnosis. In each case the finding of anti-neutrophil cytoplasm antibodies (ANCA) strongly suggested an underlying vasculitic pathology, Wegener's granulomatosis. We discuss reasons for the difficulty in diagnosis in the past, the possible role of the ANCA assay in such patients, and suggest it should be more widely used in the future.
DNA content and proliferative activity of myoepitheliomas
Authors: El-Naggar A. , Batsakis J. G. , Luna M. A. , Goepfert H. , Tortoledo M. E. 
Published: November 2007

AbstractThis report adds 16 myoepitheliomas of salivary glands to the 47 already recorded in the literature. It includes, for the first time, a flow cytometric analysis of their ploidy (DNA content) and proliferative capacity (S-phase fraction). Thirteen myoepitheliomas were diploid; three were aneuploid in their DNA content. A high proliferative capacity was always associated with an abnormal DNA content. Only one diploid myoepithelioma had a high S-phase fraction. Both flow-cytometric parameters are good predictors of an aggressive biological behaviour. Recurrences, however, were all the outcome of incomplete primary removal of the myoepitheliomas. Four of the twelve (33 per cent) diploid myoepitheliomas recurred and one, with high S-phase fraction, led to the death of the patient. Two of the three (67 per cent) aneuploid myoepitheliomas recurred. Extensive loco-regional invasion by one killed the patient. The other has clinical evidence of distant metastasis.
Carcinoma of the nasal vestibule: Report of 12 cases
Authors: Barzan L. , Franchin G. , Frustaci S. , De Paoli A. , Comoretto R. 
Published: November 2007

AbstractCarcinoma of the nasal vestibule has an individual clinical character; in this retrospective analysis the data of 12 consecutive patients are reported. Small lesions were treated by surgical resection and larger tumours by intra-arterial chemotherapy (IAC) followed by external beam radiotherapy. One patient had a recurrence which was successfully treated surgically; six had previous or subsequent malignancies. The results of the most recent series reported in the literature are reviewed and the rationale of the IAC approach is discussed. The reported treatment policy seems effective in achieving the highest cure rate with the best functional results.
Nasopharyngeal carcinoma with secondaries at the porta hepatis presenting as obstructive jaundice
Authors: Elango S. , Jayakumar C. R. 
Published: November 2007

AbstractRecent reports have dispelled the previously held concept that head and neck cancer rarely metastases beyond the cervical lymph nodes. Nasopharyngeal cancer has been reported to have a higher incidence of distant metastases compared to other head and neck cancers, the common sites being bone, lung and liver. A case of nasopharyngeal carcinoma presenting as obstructive jaundice because of secondaries at the porta hepatis is presented here.
Metastatic salivary pleomorphic adenoma
Authors: Sim David W. , Maran Arnold G. D. , Harris Douglas 
Published: November 2007

AbstractPleomorphic adenomas of the salivary gland are usually regarded as benign tumours. We report a case in which a solitary pulmonary metastasis arose from a pleomorphic adenoma of the right parotid gland. The mechanism of metastasis is discussed.
Value of middle ear inflation as a diagnostic indicator of eustachian tube patency
Authors: Luntz M. , Sadé J. 
Published: November 2007

AbstractThe value of tubal inflation as a diagnostic procedure for Eustachian tube patency and function is controversial. In an attempt to assess the diagnostic value of air douche in atelectatic ears, 49 such ears of 40 patients were politzerized. The procedure was successful in 45 ears. However, of the four unsuccessful cases, two of the patients were able to autoinflate their ears. These results show that air douches pass regularly through the Eustachian tube into the tympanic cavity even in atelectatic ears, which by definition suffer from aeration deficiency, which is often considered to be secondary to ‘Eustachian tube obstruction’, or alternatively ‘Eustachian tube dysfunction’. Thus, the ability to force air through the Eustachian tube by politzerization is of no diagnostic value as an indicator of normal or abnormal tubal patency or functioning in atelectatic ears and most probably in allied conditions.
Laryngeal amyloidosis
Authors: Talbot A. R. 
Published: November 2007

AbstractLaryngeal amyloidosis is a rare disease. Surgery has been the mainstay of treatment either endoscopically or by an external neck approach. In more recent years, surgery with the carbon dioxide laser has been advocated for this condition. Four cases of laryngeal amyloidosis are presented. The application and the advantages of the carbon dioxide laser for the treatment of laryngeal amyloidosis are discussed.