bluuebunny/crossref_metadata_2025_split huggingface dataset:
Changing food choices: the option for high-protein foods and the move away from the Mediterranean diet
Authors: Vaccaro Concetta M , Guarino Giulia , Danza Francesco , Fraulino Alessia , Bracale Renata 
Published: March 2024

Abstract
The growing importance placed on health and physical well-being by consumers continues to drive the choices of the food industry in favor of offering new products that pander to proclivities toward foods deemed more healthy and able to impact the most coveted body image, that of the lean and athletic body. It is evidenced, thus, a change in food choices and habits, with more attention to the quality and nutrient content of the products consumed, in which protein is assuming increasing importance.
Purpose: The purpose of the study is to highlight important changes in eating habits and in particular the increase in the consumption of high-protein foods, attributable to the focus on physical fitness and thinness, resulting in a decreasing adherence to the Mediterranean diet and the progressive loss of its positive impact on health.
Methods and Results: This analysis is based on CIRCANA srl data on food consumption trends (change percentage of quantity and value sales) in recent years. Specifically, between January and September 2022 vs. 2021, there was a 21.6% increase in the sale of high-protein products, significantly higher than all the previous ones.
Conclusion: The past few years have seen the gradual discovery of new products, at first little-known and niche, which are becoming major players on the national food consumption scene. The trend is toward an growing preference for highprotein foods and diets with the gradual abandonment of the Mediterranean and an increased risk of nutritional deficiencies, obesity, and cardiovascular disease.
Level of evidence: Level IV, evidence obtained from multiple time series with or without the intervention
GAPS II: Development and Pilot Results of the Global Assessment in Pediatric Surgery, an Evidence-Based Pediatric Surgical Capacity Assessment Tool for Low-Resource Settings
Authors: Yousef Yasmine , Cairo Sarah , St-Louis Etienne , Goodman Laura F. , Hamad Doulia M. , Baird Robert , Smith Emily R. , Emil Sherif , Laberge Jean-Martin , Abdelmalak Mohamed , Gathuy Zipporah , Evans Faye , Adel Maryam Ghavami , Bertille Ki K. , Chitnis Milind , Millano Leecarlo , Nthumba Peter , d'Agostino Sergio , Cigliano Bruno , Zea-Salazar Luis , Ameh Emmanuel , Ozgediz Doruk , Guadagno Elena , Poenaru Dan 
Published: March 2024

Abstract
PURPOSE:
Pediatric surgical care in low- and middle-income countries is often hindered by systemic gaps in healthcare resources, infrastructure, training, and organisation. This study aims to develop and validate the Global Assessment of Pediatric Surgery (GAPS) to appraise pediatric surgical capacity and discriminate between levels of care across diverse healthcare settings.
METHODS:
The GAPS Version 1 was constructed through a synthesis of existing assessment tools and expert panel consultation. The resultant GAPS Version 2 underwent international pilot testing. Construct validation categorized institutions into providing Basic or Advanced Surgical Care. GAPS was further refined to Version 3 to include only questions with a > 75% response rate and those that significantly discriminated between Basic or Advanced Surgical settings.
RESULTS:
GAPS Version 1 included 139 items, which, after expert panel feedback, was expanded to 168 items in Version 2. Pilot testing, in 65 institutions yielded a high response rate. Of the 168 questions in GAPS Version 2, 64 significantly discriminated between Basic and Advanced Surgical Care. The refined GAPS Version 3 tool comprises 64 questions: Human Resources (9), Material Resources (39), Outcomes (3), Accessibility (3), and Education (10).
CONCLUSION:
The GAPS Version 3 tool presents a validated instrument for evaluating pediatric surgical capabilities in low-resource settings.
Research status of the Mendeleev Periodic Table: a bibliometric analysis
Authors: Sharma Kamna , Das Deepak Kumar , Ray Saibal 
Published: March 2024

Abstract
In this paper, we present a bibliometric analysis of the Mendeleev Periodic Table. We have conducted a comprehensive analysis of Scopus based database using the keyword “Mendeleev Periodic Table”. Our findings suggest that the Mendeleev Periodic Table is an influential topic in the field of Inorganic as well as Organic Chemistry. Future researcher may focus on expanding our analysis to include other bibliometric indicators to gain a more comprehensive understanding of the impact of the Mendeleev Periodic Table in the chemistry-based scientific investigations and even in the field of astrochemistry.
Genipa americana lectin (GaBL) induces inhibition of growth, migration, invasion, and regulation of the expression of caspase-mediated apoptosis and proteins related to the development of cancer in human head and neck cells
Authors: Costa Ricardo Bezerra , Silva Monizy da Costa , Gomes Emisael Stênio Batista , Rocha Rogério Gonçalves , de Queiroz Stella Freitas , Santos Marta Angelo dos , Duarte Ana Kelly da Silva Fernandes , Guimarães André Luiz Sena , Pereira Hugo Juarez Vieira , Fraga Carlos Alberto de Carvalho , Gomes Francis Soares 
Published: March 2024

Abstract
The antitumor activity of Genipa americana bark lectin (GaBL) was evaluated for the first time against cell lines of human skin cancer (A431), melanoma (B16), and squamous cell carcinoma of the tongue (SCC9). Cancer cell lines were treated with 10 µg/ml of GaBL to assess cell viability, cell migration and invasion, as well as the identification of cell membrane alterations associated with apoptosis. Real-time polymerase chain reaction for caspase-3 was performed to verify if apoptosis is activated by lectin treatment. The mRNA expression of proteins (E-cadherin, type I collagen) related to the epithelial-mesenchymal transition was also analyzed. GaBL decreased (27.5–50%) cell proliferation and reduced cell migration in all strains evaluated. Additionally, the lectin decreased the invasion of SCC9 cells. Apoptosis was higher against B16 and SCC9 cells treated with the lectin. GaBL induced the upregulation of caspase-3, E-cadherin and suppression of type I collagen in all strains tested, indicating lower cancer development. GaBL induces inhibition of growth, migration, invasion, and regulation of the expression of caspase-mediated apoptosis and proteins related to the development of cancer in human head and neck cells.
Use of a new vertical traction device for early traction-assisted staged closure of congenital abdominal wall defects: a prospective series of 16 patients
Authors: Ziegler Anna-Maria , Svoboda Daniel , Lüken-Darius Britta , Heydweiller Andreas , Falk Sophie Christine , Kahl Fritz , Rolle Udo , Theilen Till-Martin 
Published: March 2024

Abstract
Purpose Abdominal wall closure in patients with giant omphalocele (GOC) and complicated gastroschisis (GS) remains to be a surgical challenge. To facilitate an early complete abdominal wall closure, we investigated the combination of a staged closure technique with continuous traction to the abdominal wall using a newly designed vertical traction device for newborns (fasciotens®Pediatric).
Methods Four tertiary pediatric surgery departments participated in the study between 04/2022- 11/2023. In case primary organ reduction and abdominal wall closure were not amenable, patients underwent a traction-assisted abdominal wall closure applying fasciotens®Pediatric. Outcome parameters were time to closure, surgical complications, infections, and hernia formation.
Results Ten patients with GOC and 6 patients with GS were included. Complete fascial closure was achieved after a median time of 7 days (range 4-22) in GOC and 5 days (range 4-11) in GS. There were two cases of tear-outs of traction sutures and one skin suture line dehiscence after fascial closure. No surgical site infection or signs of abdominal compartment syndrome were seen. No ventral or umbilical hernia occurred after a median follow-up of 12 months (range 4-22).
Conclusion Traction-assisted staged closure using fasciotens®Pediatric enabled an early tension-less fascial closure in GOC and GS in the newborn period.
Research on protein and peptides in scorpion based on transcriptomics- proteomics-peptidomics integrated association analysis strategy
Authors: Gao Fan , Li Hong-jing , Zhao Xin-meng , Shi Ci-ci , Liu Xing-chao , Guo Qiu-hong , Jiang Jian-ming 
Published: March 2024

Abstract
Background: To preliminarily elucidate the possible molecular basis of scorpion efficacy through the methods of transcriptomic-proteomic-peptidomics.
Methods: The transcriptome data of scorpion were obtained by high-throughput sequencing and analyzed by bioinformatics to establish the protein prediction database of scorpion. Furthermore, the proteomics and peptidomics of scorpion were analyzed by LC-MS analysis, and the GO annotation and KEGG pathway function enrichment analysis were performed for the identified proteins to explore the material basis of the efficacy of scorpion.
Results: A total of 17605 gene sequences were obtained by transcriptome sequencing, and 12368 proteins could be predicted. 278 transcription factors and 51 family information of transcription factors were obtained through database comparison. From GO and KEGG annotation results, it was found that scorpion had functions such as regulating cell cycle, amino acid metabolism and signal transduction, which may be closely related to the analgesic and anti-cancer functions of scorpion. In the process of proteome identification, 10,072 peptides were found, and 1917 protein components were deduced from these peptides. For the identification of peptides, 6758 peptides were matched in the transcriptome database and 33,834 peptides were identified by de novo sequencing. The results showed that the scorpion proteins were mainly enriched in protein translation, tricarboxylic acid cycle and glycolysis, and the KEGG pathway was mainly enriched in oxidative phosphorylation, amino acid metabolism and ribosome.
Conclusions: A total of 33834 peptides and 1917 proteins were identified from scorpion by integrated transcriptomic-proteomics-peptidomics association analysis. GO annotation and KEGG pathway functional enrichment analysis showed that the macromolecular components of scorpion were mainly related to oxidative phosphorylation, amino acid metabolism and immune regulation.
Impact of hyperbolic-cut twisted tape on heat transfer, friction factor and thermohydraulic performance of heat exchanger tube: An experimental study using Internet of things (IoT) approach
Authors: Rajan Abhijit 
Published: March 2024

Abstract
In this experimental investigation, our primary objective was to assess the collective impact of hyperbolic-cut depth and width cuts on twisted tape (TT) inserts within a heat exchanger tube (HET) operating under laminar flow conditions encompassing a Reynolds number (Re) range of (100 ≤ Re ≤ 1500). The insert utilized featured hyperbolic cuts along its edges of tape. The hyperbolic-cut depth and cut width were varied between (3 mm ≤ b ≤ 12 mm) and (10 mm ≤ c ≤ 16 mm) for a constant twist ratio. To minimize inaccuracies and enhance automation, we implemented the Internet of Things (IoT) methodology to monitor supplementary input and output variables and measure flow rates. This method produced more dependable outcomes by reducing the need for human involvement. The results of the current investigation suggest that specific alterations to the TT configuration resulted in a noteworthy enhancement in heat transfer efficiency, friction factor, and overall thermohydraulic performance metrics. The enhancements were notable, showcasing a rise in the Nusselt number varying from 43.42% to 529.50 % and elevation in the friction factor spanning 136.74 to 738.40 %, respectively, when compared to the plain tube. At Re = 1500, c = 16 mm yields the best performance of 4.43. Moreover, an exhaustive examination uncovered outstanding performance across all Re compared to prior research. In addition, empirical correlations have been established for predicting the Nusselt number and friction factor. Furthermore, research efforts were dedicated to investigating the flow and thermal behaviors through experimental work to enhance our comprehension of heat transfer mechanisms.
A literature review of interventions for the prevention of empathic distress and burnout in medical trainees
Authors: Rahman Afra , Jennings Rebecca , Wu Matthew , Hake Austin , Mazza Christina , Goradia Eshani , Mehta Krisha , Post Stephen 
Published: March 2024

Abstract

Empathic distress in medical trainees may evolve into burnout in the workplace. Medical trainees are particularly susceptible. To assist in the development and implementation of effective programs to combat empathic distress, a literature review of the various available interventions aimed at increasing compassion was conducted. An investigation into whether the mindfulness component offered any benefit to the medical trainee was also performed. Twenty relevant studies were identified and analyzed. The results indicated that interventions with a mindfulness-component were effective at improving trainee well-being and compassion, and may have an impact on burnout.
Design and testing of Hybrid Airbreathing Ion Propulsion
Authors: Saiyed Mustakim , Shah Niyati 
Published: March 2024

Abstract
The aim of this project is to develop an innovative propulsion system that combines the principles of air-breathing engine and ion propulsion to reduce the orbit of satellites to a range of 150 to 200 kilometers above the Earth's surface. The propulsion system uses two technologies, namely the ion thruster and jet engine, to create a hybrid ion propulsion system. The research involves the design and development of a three-stage ion grid system and a fuel system to achieve an exhaust velocity of 7+ meters per second. The results of the project demonstrate that the proposed hybrid airbreathing ion propulsion system can be used as propulsion system in satellites at very low Earth orbit, which is particularly useful for applications such as weather forecasting, military surveillance, and high-speed communication and for aircraft & missile propulsion system etc. In comparison to conventional propulsion systems, the hybrid airbreathing ion propulsion system offers several advantages such as higher fuel efficiency, lower operating costs and reduced environmental impact. These benefits make the hybrid airbreathing ion propulsion system a promising technology for future space missions, including satellite deployment in very low Earth orbit and for aircraft & missile propulsion system.
Unravelling the Referendum: An analysis of the 2023 Australian Voice to Parliament Referendum outcomes across capital cities
Authors: Baum Scott , Mitchell William 
Published: March 2024

Abstract
The 2023 Australian Voice to Parliament Referendum presented a pivotal moment in the nation's democratic landscape, aiming to enshrine indigenous voices in the constitutional fabric through the establishment of an Aboriginal and Torres Strait Islander Voice. Despite widespread support for indigenous well-being, the referendum did not secure the necessary approval, prompting extensive analysis of its outcome. This paper employs an ecological approach to scrutinize the referendum's dynamics, exploring six hypotheses derived from public discourse. Findings reveal multifaceted influences on voting behavior. Economic concerns, exemplified by the cost-of-living crisis, seemingly diverted attention from constitutional reform, potentially swaying votes towards maintaining the status quo. Conversely, culturally diverse communities demonstrated heightened empathy towards indigenous issues, aligning with the yes vote. Lower levels of education correlated with support for the no vote, highlighting the impact of political knowledge on decision-making. Moreover, religious conservatism and political partisanship emerged as influential factors, with Christian values and party affiliations shaping voting patterns. These findings underscore the complexity of referendum dynamics, emphasizing the importance of effective messaging and understanding diverse socio-political contexts in shaping public opinion. The defeat of the referendum marks a setback in indigenous relations, prompting critical reflection on messaging strategies and the broader socio-political landscape. This analysis provides a foundational empirical framework for understanding the referendum outcome, offering insights crucial for informed discourse and future democratic endeavours.
Prevalence of undernutrition among children with cerebral palsy aged 6-59 months in rehabilitation centers in Kampala, Uganda
Authors: Nanfuka Mary Immaculate , Dektar Benbella , Mangen Fred Wabwire , Onyait Emmanuel Ejuu , Nakazibwe Susan Kalule , Mukiza Nelson 
Published: March 2024

Abstract
Background: In Uganda, a critical health concern emerges with Cerebral Palsy (CP), affecting approximately 2.7 per 1000 children. Notably, anecdotal evidence from rehabilitation centers suggests a strong correlation between CP and the heightened risk of undernutrition and its subsequent complications in children below five years. However, the extent of undernutrition prevalence and the factors contributing to this condition among CP-afflicted children in Uganda’s rehabilitation centers remain largely unexplored.
This study aimed to ascertain the prevalence of undernutrition and identify its associated factors in a cohort of Ugandan children aged 6-59 months diagnosed with CP and residing in selected rehabilitation centers (RCs).
Methods: In accordance with the WHO Growth Chart (2006) as a benchmark, the study delineated undernutrition as a dependent variable using indicators such as height-for-age, weight-for-height, and weight-for-age with a standard deviation score of ≤ 2.0. This was accomplished through meticulous physical examinations and anthropometric measurements of 168 children. A modified Poisson regression model was utilized to pinpoint the determinants of undernutrition (independent variables), yielding prevalence ratios as a measure of association within 95% confidence intervals, complemented by multivariable logistic regression. Data analysis was conducted using STATA v.12, duly considering the survey design effects, including sampling weight.
Results: The results revealed that a majority (53.6%) of the children were aged between 12 and 35 months, with a predominance of male participants (64.3%). Caregivers, primarily female (91%), frequently exhibited financial constraints (56% had no income) and limited educational background (36% lacked formal education or had only primary school education). Alarmingly, the prevalence of undernutrition among children with CP stood at 61.2%, with stunting and underweight being the most common manifestations at 39.9% and 40.2%, respectively. Critical factors associated with undernutrition included the age bracket of 1 to 5 years—precisely, 12-35 months (adj.PR=1.49; 1.01-2.19) and above 35 months (adj.PR=1.55;1.03-2.32)—and a diet comprising less than three food groups daily, significantly increasing the risk of undernutrition.
Conclusion: In conclusion, this study highlights a disturbingly high prevalence of undernutrition (61.2%) among children aged 6-59 months with CP in Ugandan rehabilitation centers, with stunting and underweight being the most prevalent forms.
Mosquito Repellence of Solvent Extracts andActivated Charcoal Obtained from Agro-WasteCoconut Shells
Authors: Baindur Siddharth , Gohil Rinkesh , Kolte Satish 
Published: March 2024

Abstract
Description of the Subject
Burning coconut shells have been used since ages in rural India to ward away mosquitoes; we studied this traditional method in detail in our research using modern techniques such as dry distillation, solvent extraction, chromatography and infrared spectroscopy to decipher its constitution and efficacy.
Objectives
In our research, coconut shells in the form of activated charcoal and chemical extracts obtained from the shell were used to test their mosquito (Aedes aegyptii) repellence and knockdown efficacy using distinct methods.
Methods
Solvent extraction, fractional distillation, column chromatography, Fourier transform infrared spectroscopy, and Peet Grady’s chamber were used as per the WHO guidelines for testing insecticides.
Results
The petroleum ether extract from the solvent extraction technique was found to be most effective, with a 100% mortality rate after 30 mins. The extract mainly contained aromatic compounds, alkanes and ketonic groups.
Conclusion
Activated charcoal obtained from agro-waste coconut shells can be used as an alternative filler in industrially manufactured mosquito coils. The petroleum extract can be used as a great mosquito repellent in contrast to hazardous chemicals already present in the coils.
Risk factors and practices associated with occurrence of Urinary Tract Infections in Sub-Saharan Africa; A scoping review
Authors: Kimani Moses Karanja 
Published: March 2024

Abstract
Introduction
Urinary Tracts Infections remain a major public health challenge with a particular higher burden in Sub-Saharan Africa. There remains a dearth of information in literature regarding patterns of risk factors and practices associated with Urinary Tract Infections in Sub-Saharan Africa. This scoping review aimed at documenting the risk factors and practices associated with Urinary Tract Infections in Sub-Saharan Africa.
Methods
A systematic search of databases was done under the guidelines outlined by Joanna Brigs Institute to retrieve original articles that met inclusion criteria. Standard bibliographic information for articles that met the inclusion criteria was recorded in an Excel spreadsheet and then exported to SPSS version 21for statistical analysis. Biographic information, risk factors, and practices findings from statistical analysis were presented in tables, bar graphs and charts, followed by a summarized narrative account of the risk factors and practices that emerged. Reporting was conducted in accordance with preferred reporting items for systematic review and meta-analysis extension for scoping reviews (PRISMA-ScR).
Results
Out of the 794 studies identified, 31 studies met inclusion criteria. Studies included in this review were distributed in 9 countries, Ethiopia leading with 38.7% (n = 12), Nigeria followed with 25.8% (n = 8), Uganda 9.7% (n = 3), Cameroon and Kenya each contributed 6.5% (n = 2), and Ghana, Tanzania, Burkina Faso and Zambia each contributed 3.2% (n = 1). Twenty one risk factors and three practices were identified to be associated with Urinary Tract Infections in Sub-Saharan Africa.
Conclusion
The current evidence demonstrated the dire need for future studies to lay more emphasis on methodological and statistical rigor. Particularly, this scoping review identified the need to further investigate practices which wee underinvestigated. Further, methodological and statistical rigor should be emphasized by future studies.