bluuebunny/crossref_metadata_2025_split huggingface dataset:
Changes in faecal haemoglobin values over sequential rounds of faecal immunochemical tests (FIT) in a surveillance population
Authors: Mortell Gemma , Wooldrage Kate , Murphy Gwen A , Cross Amanda J 
Published: February 2025

ObjectiveColorectal cancer (CRC) screening enables resection of polyp precursor lesions, preventing cancer or detecting it earlier. Post-polypectomy, people can remain at increased CRC risk, prompting surveillance colonoscopy. Less invasive faecal immunochemical tests (FIT) could reduce the burden of surveillance colonoscopy. We investigated whether changes in FIT values over multiple rounds were associated with advanced colorectal neoplasia (ACN) detection.MethodsA cohort of men and women aged 60–72 years deemed intermediate risk by the 2002 UK adenoma surveillance guidelines and scheduled for three yearly colonoscopies were recruited (January 2012–December 2013) within the English Bowel Cancer Screening Programme and offered a quantitative FIT at 1, 2 and 3 years post-baseline colonoscopy for a prospective analysis within a diagnostic accuracy study. Participants positive (≥40 µg haemoglobin/g faeces) at 1 year or 2 years were offered early colonoscopy and excluded, otherwise, colonoscopy was offered at 3 years. Only those who completed three FIT rounds and attended the 3-year colonoscopy were included. Participants were grouped based on changes between FIT rounds, with changes defined as absolute differences ≥4 µg/g, and positivity at round 3.ResultsAmong 4412 participants, the largest group (n=2773) was the no change category, which had the lowest ACN detection rate (4.7%, 95% CI: 3.9 to 5.5). The serial increase group with a positive round 3 value (n=46) had the highest ACN detection rate (32.6%, 95% CI: 19.5 to 48.0).ConclusionNo change in FIT result across multiple rounds was associated with a low ACN detection rate, while a serial increase was associated with higher ACN detection rates. Further research should consider if sequential rounds of FIT could be used for stratifying individual risk.
Development of MMC-based lithium molybdate cryogenic calorimeters for AMoRE-II
Authors: Agrawal A. , Alenkov V. V. , Aryal P. , Beyer J. , Bhandari B. , Boiko R. S. , Boonin K. , Buzanov O. , Byeon C. R. , Chanthima N. , Cheoun M. K. , Choe J. S. , Choi Seonho , Choudhury S. , Chung J. S. , Danevich F. A. , Djamal M. , Drung D. , Enss C. , Fleischmann A. , Gangapshev A. M. , Gastaldo L. , Gavrilyuk Y. M. , Gezhaev A. M. , Gileva O. , Grigorieva V. D. , Gurentsov V. I. , Ha C. , Ha D. H. , Ha E. J. , Hwnag D. H. , Jeon E. J. , Jeon J. A. , Jo H. S. , Kaewkhao J. , Kang C. S. , Kang W. G. , Kazalov V. V. , Kempf S. , Khan A. , Khan S. , Kim D. Y. , Kim G. W. , Kim H. B. , Kim Ho-Jong , Kim H. J. , Kim H. L. , Kim H. S. , Kim M. B. , Kim S. C. , Kim S. K. , Kim S. R. , Kim W. T. , Kim Y. D. , Kim Y. H. , Kirdsiri K. , Ko Y. J. , Kobychev V. V. , Kornoukhov V. , Kuzminov V. V. , Kwon D. H. , Lee C. H. , Lee DongYeup , Lee E. K. , Lee H. J. , Lee H. S. , Lee J. , Lee J. Y. , Lee K. B. , Lee M. H. , Lee M. K. , Lee S. W. , Lee Y. C. , Leonard D. S. , Lim H. S. , Mailyan B. , Makarov E. P. , Nyanda P. , Oh Y. , Olsen S. L. , Panasenko S. I. , Park H. K. , Park H. S. , Park K. S. , Park S. Y. , Polischuk O. G. , Prihtiadi H. , Ra S. , Ratkevich S. S. , Rooh G. , Sari M. B. , Seo J. , Seo K. M. , Sharma B. , Shin K. A. , Shlegel V. N. , Siyeon K. , So J. , Sokur N. V. , Son J. K. , Song J. W. , Srisittipokakun N. , Tretyak V. I. , Wirawan R. , Woo K. R. , Yeon H. J. , Yoon Y. S. , Yue Q. ,   The AMoRE Collaboration
Published: February 2025

Abstract
The AMoRE collaboration searches for neutrinoless double beta decay of

$$^{100}$$

100

Mo using molybdate scintillating crystals via low temperature thermal calorimetric detection. The early phases of the experiment, AMoRE-pilot and AMoRE-I, have demonstrated competitive discovery potential. Presently, the AMoRE-II experiment, featuring a large detector array with about 90 kg of

$$^{100}$$

100

Mo isotope, is under construction. This paper discusses the baseline design and characterization of the lithium molybdate cryogenic calorimeters to be used in the AMoRE-II detector modules. The results from prototype setups that incorporate new housing structures and two different crystal masses (316 g and 517–521 g), operated at 10 mK temperature, show energy resolutions (FWHM) of 7.55–8.82 keV at the 2.615 MeV

$$^{208}$$

208

Tl

$$\gamma $$

γ

line and effective light detection of 0.79–0.96 keV/MeV. The simultaneous heat and light detection enables clear separation of alpha particles with a discrimination power of 12.37–19.50 at the energy region around

$$^{6}$$

6

Li

$$(n,\alpha )^3$$

(
n
,
α
)

3

H with Q-value = 4.785 MeV. Promising detector performances were demonstrated at temperatures as high as 30 mK, which relaxes the temperature constraints for operating the large AMoRE-II array.
Double-beta decay of $$^{150}\hbox {Nd}$$ to excited levels of $$^{150}\hbox {Sm}$$
Authors: Barabash A. S. , Belli P. , Bernabei R. , Boiko R. S. , Cappella F. , Caracciolo V. , Cerulli R. , Danevich F. A. , Fang D. L. , Ferella F. , Incicchitti A. , Kobychev V. V. , Konovalov S. I. , Laubenstein M. , Leoncini A. , Merlo V. , Nisi S. , Niţescu O. , Poda D. V. , Polischuk O. G. , Shcherbakov I. B.-K. , Šimkovic F. , Timonina A. , Tinkova V. S. , Tretyak V. I. , Umatov V. I. 
Published: February 2025

Abstract
The

$$2\nu 2\beta $$

2
ν
2
β

decay of

$$^{150}\hbox {Nd}$$

150

Nd

to the first excited 740.5 keV

$$0^{+}_{1}$$

0
1
+

level of

$$^{150}\hbox {Sm}$$

150

Sm

was measured over 5.845 years with the help of a four-crystal low-background HPGe

$$\gamma $$

γ

spectrometry system in the underground low-background laboratory STELLA of LNGS-INFN. A 2.381 kg highly purified Nd-containing sample was employed as the decay source. The expected de-excitation gamma-quanta of the

$$0^{+}_{1}$$

0
1
+

level with energies 334.0 keV and 406.5 keV were observed both in one-dimensional spectrum and in coincidence data resulting in the half-life

$$T_{1/2}=[0.83^{+0.18}_{-0.13}\mathrm {(stat)}^{+0.16}_{-0.19}\mathrm {(syst)}]\times 10^{20}$$

T

1
/
2

=

[
0
.

83

-
0.13

+
0.18

(
stat
)

-
0.19

+
0.16

(
syst
)

]

×

10
20

year. Interpreting an excess of the 334.0-keV peak area as an indication of the

$$2\beta $$

2
β

decay of

$$^{150}\hbox {Nd}$$

150

Nd

to the 334.0 keV

$$2^+_1$$

2
1
+

excited level of

$$^{150}\hbox {Sm}$$

150

Sm

with a half-life of

$$T_{1/2}=[1.5^{+2.3}_{-0.6}\mathrm {(stat)}\pm 0.4\mathrm {(syst)}]\times 10^{20}$$

T

1
/
2

=

[
1
.

5

-
0.6

+
2.3

(
stat
)

±
0.4

(
syst
)

]

×

10
20

year, the

$$2\nu 2\beta $$

2
ν
2
β

half-life of

$$^{150}\hbox {Nd}$$

150

Nd

for the transition to the 0

$$^{+}_{1}$$

1
+

level is

$$T_{1/2}=[1.03^{+0.35}_{-0.22}\mathrm {(stat)}^{+0.16}_{-0.19}\mathrm {(syst)}]\times 10^{20}$$

T

1
/
2

=

[
1
.

03

-
0.22

+
0.35

(
stat
)

-
0.19

+
0.16

(
syst
)

]

×

10
20

year, in agreement with the previous experiments. Both half-life values reasonably agree with the theoretical calculations in the framework of proton-neutron QRPA with isospin restoration combined with like nucleon QRPA for description of excited states in the final nuclei. For

$$2\nu 2\beta $$

2
ν
2
β

and

$$0\nu 2\beta $$

0
ν
2
β

transitions of

$$^{150}\hbox {Nd}$$

150

Nd

and

$$^{148}\hbox {Nd}$$

148

Nd

to several excited levels of

$$^{150}\hbox {Sm}$$

150

Sm

and

$$^{148}\hbox {Sm}$$

148

Sm

, limits were set at level of

$$T_{1/2}>10^{20}-10^{21}$$

T

1
/
2

>

10
20

-

10
21

year.
BCviz: A Linear-Space Index for Mining and Visualizing Cohesive Bipartite Subgraphs
Authors: Ye Jianxiong , Zou Zhaonian , Liu Dandan , Yang Bin , Liu Xudong 
Published: February 2025

Finding the maximum biclique in a bipartite graph is a fundamental graph analysis problem. Existing methods for maximum biclique search are not very efficient because they cannot effectively reduce the size of a bipartite graph composed of large bicliques that are loosely linked together because the graph reduction strategies adopted by these methods only consider local densities of vertices.
This paper proposes a novel approach to maximum biclique search. The unique feature of this approach is building a linear-space data-driven index called BCviz that helps accurately identify subgraphs containing all bicliques with sizes no less than a certain threshold. The core technique of BCviz is determining a total order of vertices that can reveal both the local density and the connectivity of the vertices. Notably, our work is the first one to take connectivity into account in graph reduction. Interestingly, the total order of vertices entails BCviz an illustrative visualization of the distribution of cohesive subgraphs in the input graph.
To deeply understand BCviz, we carry out a theoretical study on its properties and reveal how it enables more effective graph reduction. Based on BCviz, we propose an exact maximum biclique search algorithm that searches for results on much smaller subgraphs than any existing method does.
In addition, we improve the efficiency of index construction by two techniques. One is approximating an edge's local density with an upper bound that can be derived in linear time. The other is a lightweight vertex ordering method called one-spot ordering which reduces unnecessary cohesion computations.
Extensive experiments indicate that the proposed maximum biclique search methods based on BCviz and its variants outperform the state-of-the-art search-based methods by 2--3 orders of magnitude. Compared with the state-of-the-art index for maximum biclique search, the improved BCviz index can reduce the index size by 1--2 orders of magnitude and the index construction time by up to 2 orders of magnitude.
CRDV: Conflict-free Replicated Data Views
Authors: Faria Nuno , Pereira José 
Published: February 2025

There are now multiple proposals for Conflict-free Replicated Data Types (CRDTs) in SQL databases aimed at distributed systems. Some, such as ElectricSQL, provide only relational tables as convergent replicated maps, but this omits semantics that would be useful for merging updates. Others, such as Pg\_crdt, provide access to a rich library of encapsulated column types. However, this puts merge and query processing outside the scope of the query optimizer and restricts the ability of an administrator to influence access paths with materialization and indexes.
Our proposal, CRDV, overcomes this challenge by using two layers implemented as SQL views: The first provides a replicated relational table from an update history, while the second implements varied and rich types on top of the replicated table. This allows the definition of merge semantics, or even entire new data types, in SQL itself, and enables global optimization of user queries together with merge operations. Therefore, it naturally extends the scope of query optimization and local transactions to operations on replicated data, can be used to reproduce the functionality of common CRDTs with simple SQL idioms, and results in better performance than alternatives.
DEG: Efficient Hybrid Vector Search Using the Dynamic Edge Navigation Graph
Authors: Yin Ziqi , Gao Jianyang , Balsebre Pasquale , Cong Gao , Long Cheng 
Published: February 2025

Bimodal data, such as image-text pairs, has become increasingly prevalent in the digital era. The Hybrid Vector Query (HVQ) is an effective approach for querying such data and has recently garnered considerable attention from researchers. It calculates similarity scores for objects represented by two vectors using a weighted sum of each individual vector's similarity, with a query-specific parameter α to determine the weight. Existing methods for HVQ typically construct Approximate Nearest Neighbors Search (ANNS) indexes with a fixed α value. This leads to significant performance degradation when the query's α dynamically changes based on the different scenarios and needs.
In this study, we introduce the Dynamic Edge Navigation Graph ( DEG ), a graph-based ANNS index that maintains efficiency and accuracy with changing α values. It includes three novel components: (1) a greedy Pareto frontier search algorithm to compute a candidate neighbor set for each node, which comprises the node's approximate nearest neighbors for all possible α values; (2) a dynamic edge pruning strategy to determine the final edges from the candidate set and assign each edge an active range. This active range enables the dynamic use of the Relative Neighborhood Graph's pruning strategy based on the query's α values, skipping redundant edges at query time and achieving a better accuracy-efficiency trade-off; and (3) an edge seed method that accelerates the querying process. Extensive experiments on real-world datasets show that DEG demonstrates superior performance compared to existing methods under varying α values.
Decentralised Privacy-Preserving Power Flow Forecast on Smart Meters
Authors: Nowak Severin , Widmer Fabian , Taylor Jeremy , Raimundo Daniel , Papaemmanouil Antonios 
Published: February 2025

The transition toward decarbonisation of energy systems necessitates significant adaptations in distribution networks, challenging the grid planning and operation for Distribution System Operators (DSOs). This paper explores how smart meters can improve DSO capabilities amidst evolving regulatory frameworks and technological landscapes. DSOs face the challenge of accommodating more distributed generation, electrification of loads, and the surge in electric vehicles, all while striving to maintain grid reliability and cost-effectiveness. To meet these demands without compromising data security and privacy, advanced data science techniques are explored, leveraging smart meter data in near real-time.
The paper proposes decentralised algorithms capable of near real-time computation and forecasting of network power flows, revealing congestion issues without centralising consumer data. Field trials conducted in Rolle VD provide concrete evidence of the feasibility and advantages of this approach. They not only offer insights into network conditions but also ensure data privacy. Moreover, the developed decentralised congestion calculation method has shown to deliver results comparable to commonly used centralised algorithms, even when confronted with real-world challenges such as connection issues. Utilizing smart meters with enhanced computing capabilities and Internet of Things (IoT) infrastructure, the proposed method presents a viable alternative to traditional approaches, enabling DSOs to adapt to the evolving energy landscape efficiently.
FoSSaCS 2024: Report of the Program Chairs
Authors: Kobayashi Naoki , Worrell James 
Published: February 2025

The 27th edition of the Foundations of Software Science and Computation Structures (FoSSaCS) took place in Luxembourg City as part of the European Joint Conferences on Theory and Practice of Software (ETAPS), held from April 6 to 11, 2024.
The conference received 108 submissions, of which 28 were accepted. Each paper underwent a careful evaluation by at least three members of the program committee, ensuring a high standard of review. Following the rebuttal period, there was a lively PC discussion which culminated in an online PC meeting to finalise the decisions. The chosen papers represented a broad cross-section of foundational topics related to programming and computer systems, including automata, games, logic, verification, concurrency theory, type theory, and categorical semantics.
Assessment of the Correlation Between Renal Function Markers and Serum Ferritin Levels in Thalassemia Patients
Authors: Tammadondar Mohammad , Vatankhah Ali , Khatibzade-Nasari Niloufar 
Published: February 2025

Background: This study aimed to analyze renal function markers and correlate the results with serum ferritin levels in patients with thalassemia in Bandar Abbas, Iran, in 2020.Method: A cross‐sectional study was conducted, and patients with a proven hemoglobinopathy diagnosis were included. Fasting blood was obtained to measure creatinine, sodium, potassium, calcium, phosphorus, magnesium, uric acid, and ferritin. In addition, a 24‐h urine specimen was collected to determine the level of urine albumin, creatinine, sodium, potassium, calcium, phosphorus, magnesium, uric acid, and β2‐microglobulin. Fractional excretion of sodium, potassium, calcium, phosphorus, magnesium, and uric acid was also calculated. Spearman’s coefficient of correlation was used to determine the correlations between serum ferritin level and other variables.Results: Of the sixty‐six patients studied, 3.0% had sickle cell thalassemia, 80.3% had major thalassemia, and 72.7% had intermediate thalassemia. In our study, serum ferritin, 24‐h urine protein, and fractional excretion of sodium, calcium, and urine were higher than the normal range in thalassemia patients. There was a significant correlation between serum ferritin level and fractional excretion of magnesium, calcium, sodium, phosphorus, and uric acid with a negative correlation coefficient (p ≤ 0.05). We also found that the serum ferritin levels strongly correlated with microalbuminuria (p ≤ 0.05).
Understanding Moral Courage From Nurse Leaders’ Perspectives: A Qualitative Exploration
Authors: Huang Mingtao , Ouyang Yanzhen , Huang Qiuyu , Xu Guiru 
Published: February 2025

Background: The stance of nurse leaders toward moral courage and encouragement received from them hold significant sway in determining whether nurses can courageously uphold the correct values in their duties and actions.Aim: The objective of this study is to gain insights into nurse leaders’ perceptions of moral courage in the workplace, with the aim of addressing barriers to the development of moral courage among nurses.Research Design: This study used descriptive qualitative methods in accordance with the Consolidated Criteria for Reporting Qualitative Studies (COREQ).Participants and Research Context: This study was conducted in 2024. Participants were selected by purposive sampling. The sample size was determined by data saturation, which was reached with 10 participants. The interviews were conducted through semistructured telephone interviews. Data were analyzed using a deductive method of content analysis.Ethical Considerations: The ethics committee of Fujian Medical University (No. 196, 2024) provided approval for this study. Verbal consent was obtained before the interview with the participants. All data were processed anonymously and confidentially.Results: The analysis resulted in 14 subcategories, which were subsequently grouped into 4 categories.Conclusions: This study emphasizes the essential role of nurse leaders in promoting moral courage within healthcare teams. By fostering an ethical environment and providing support, nurse leaders enable nurses to make ethically sound decisions. Future research could further explore the longitudinal development of moral courage in nursing practice to understand the impact of moral courage on healthcare outcomes.
Staphylococcus epidermidis: Antimicrobial Resistance Profiles of Biofilm‐Forming Isolates From Pediatric Bacteremia in Pakistan
Authors: Nisar Maleeha , Rahman Hazir , Ahmad Saghir , Tabassum Tabassum , Alzahrani Khalid J. , Alzahrani Fuad M. , Alsharif Khalaf F. 
Published: February 2025

Background: Staphylococcus epidermidis is an important cause of nosocomial infections in children. The study undertaken identified antibiotic resistance markers among biofilm‐forming S. epidermidis.Methods: A total of 105 bacteremia‐positive samples from hospitalized children were processed for identification of S. epidermidis using species‐specific rdr gene. Phenotypic antibiotic resistance was checked through Kirby–Bauer disc diffusion method. 96‐well microtiter plate assays and PCR were used for biofilm production and antibiotic‐resistant genes, respectively.Results: Among 105 clinical isolates, rdr gene was detected in 34 (32.38%) isolates. The rdr detected isolates exhibited biofilm formation (n = 34; 100%). Multidrug‐resistant (MDR) pattern was observed among S. epidermidis, while the frequency of MDR was higher in very strong biofilm‐forming S. epidermidis (n = 18; 52.9%, p ≤ 0.002) as compared to weak biofilm‐forming S. epidermidis (n = 6; 17.6%). All S. epidermidis strains were resistant to cefoxitin, penicillin, and augmentin (n = 34; 100%). High resistance was observed against erythromycin (n = 29; 85.29%) and ciprofloxacin (n = 25; 73.5%). S. epidermidis displayed complete susceptibility (n = 34; 100%) toward vancomycin, tetracycline, and linezolid. Among the S. epidermidis isolates, the methicillin resistance gene (mecA, n = 29; 85.2%, p ≤ 0.000), the erythromycin resistance gene (msrA, n = 19; 55.7%) and the beta‐lactamase resistance gene (blaZ, n = 17; 50%) were detected. Detection of mecA (n = 17; 94.4%), msrA (n = 8; 44.4%) and blaZ (n = 11; 61.1%) significantly (p ≤ 0.0052) correlated with very strong biofilm‐forming S. epidermidis.Conclusion: Biofilm formation is significantly associated with antibiotic resistance. The study’s result will help to understand the molecular mechanism of antimicrobial resistance in biofilm‐forming S. epidermidis among pediatric patients.
Effects of SWEEPS‐Activated Irrigation and Other Methods for Elimination of Intracanal Medicaments on Push‐Out Bond Strength of NeoMTA2 to Root Dentin: An In Vitro Study
Authors: Babaahmadi Maryam , Dibaji Fatemeh , Vatanpour Mehdi , Aminsobhani Mohsen , Sarraf Pegah , Khoshkhounejad Mehrfam 
Published: February 2025

Objectives: This study evaluated the effects of laser‐assisted irrigation, conventional syringe irrigation (CSI), and passive ultrasonic irrigation (PUI) for elimination of intracanal medicaments on push‐out bond strength (PBS) of NeoMTA2 to root dentin.Materials and Methods: In this in vitro study, 150 extracted single‐rooted mandibular premolars were decoronated and standardized with a certain root length. The canals were instrumented to simulate immature roots and randomly assigned to three experimental groups (n = 45) using either triple antibiotic paste (TAP), double antibiotic paste (DAP), or calcium hydroxide (CH) as intracanal medicament and one no‐medicament control group (n = 15). After 28 days, the experimental groups were randomly divided into three subgroups (n = 15) according to the irrigation method using either erbium‐doped yttrium aluminum garnet (Er:YAG) laser shockwave‐enhanced emission photoacoustic streaming (SWEEPS), CSI, or PUI. A dentinal ring was then obtained from the coronal part of each root, and its lumen was densely filled with NeoMTA2. After 1 week, the PBS was measured using a universal testing machine. Data were analyzed by ANOVA and Tukey and Dunnett tests (alpha = 0.05).Results: The interaction effect of the irrigation technique and medicament type on PBS was significant (p < 0.05). The PBS in all groups was significantly lower than the control group (p < 0.01) except in CH‐SWEEPS (p = 0.741). In the experimental groups, the PBS of the SWEEPS subgroup was significantly higher than other subgroups (p < 0.001). The PBS of PUI was higher than CSI in CH and TAP groups (p < 0.001). The PBS of CH was significantly higher than TAP in CSI, and DAP and TAP in PUI and SWEEPS groups (p < 0.05).Conclusion: In this in vitro study, regardless of the irrigation method, higher PBS of NeoMTA2 to root dentin was achieved in CH groups compared to TAP. A higher PBS was also achieved when SWEEPS and PUI methods were used to eliminate CH in comparison to TAP and DAP.