bluuebunny/crossref_metadata_2025_split huggingface dataset:
A Hybrid‐Salt Strategy for Modulating the Li+ Solvation Sheathes and Constructing Robust SEI in Non‐Flammable Electrolyte Lithium Metal Batteries
Authors: Lan Kai , Zhang Xinan , Yang Xinxin , Hou Qing , Yuan Ruming , Zheng Mingseng , Fan Jingmin , Qiu Xinping , Dong Quanfeng 
Published: March 2024

AbstractThe electrode interface determines the performance of an electrochemical energy storage system. Using traditional electrolyte organic additives and high‐concentration electrolyte emerging recently are two generally strategies for improving the electrode interface. Here, a hybrid‐salt electrolyte strategy is proposed for constructing the stable electrode interface. Through the solubilization effect of phosphate ester on LiNO3, a hybrid‐salts‐based non‐flammable phosphate ester electrolyte system (HSPE) with LiPF6 and LiNO3 as Li salts has been developed. By the strong interaction between NO3− and Li+, the Li+ solvation sheath and solvent behaviors have been modulated, thus the undesirable effects of phosphate ester are eliminated and a robust SEI is formed. Experimental results and theoretical calculations illustrate that NO3− as a kind of strongly coordinating anion can reduce the number of TEP molecules and lower the reduction reactivity of TEP. The reconfigured Li+ solvation structure allows the formation of an inorganic‐rich SEI on the electrode surface. As a result, in the designed HSPE, the average coulombic efficiency of lithium plating/stripping is increased to 99.12 %. This work explored a new approach to construct the electrode interface and addressing the poor interface performance issue of phosphate esters.
Cerebellar granule cell migration and folia development require Mllt11/Af1q/Tcf7c
Authors: Blommers Marley , Stanton‐Turcotte Danielle , Witt Emily A. , Heidari Mohsen , Iulianella Angelo 
Published: March 2024

AbstractThe organization of neurons into distinct layers, known as lamination, is a common feature of the nervous system. This process, which arises from the direct coupling of neurogenesis and neuronal migration, plays a crucial role in the development of the cerebellum, a structure exhibiting a distinct folding cytoarchitecture with cells arranged in discrete layers. Disruptions to neuronal migration can lead to various neurodevelopmental disorders, highlighting the significance of understanding the molecular regulation of lamination. We report a role Mllt11/Af1q/Tcf7c (myeloid/lymphoid or mixed‐lineage leukemia; translocated to chromosome 11/All1 fused gene from chromosome 1q, also known as Mllt11 transcriptional cofactor 7; henceforth referred to Mllt11) in the migration of cerebellar granule cells (GCs). We now show that Mllt11 plays a role in both the tangential and radial migration of GCs. Loss of Mllt11 led to an accumulation of GC precursors in the rhombic lip region and a reduction in the number of GCs successfully populating developing folia. Consequently, this results in smaller folia and an overall reduction in cerebellar size. Furthermore, analysis of the anchoring centers reveals disruptions in the perinatal folia cytoarchitecture, including alterations in the Bergmann glia fiber orientation and reduced infolding of the Purkinje cell plate. Lastly, we demonstrate that Mllt11 interacts with non‐muscle myosin IIB (NMIIB) and Mllt11 loss–increased NMIIB expression. We propose that the dysregulation of NMIIB underlies altered GC migratory behavior. Taken together, the findings reported herein demonstrate a role for Mllt11 in regulating neuronal migration within the developing cerebellum, which is necessary for its proper neuroanatomical organization.
Effects of plyometric training techniques on vertical jump performance of basketball players
Authors: Pechlivanos Rafail Georgios , Amiridis Ioannis G. , Anastasiadis Nikolaos , Kannas Theodoros , Sahinis Chrysostomos , Duchateau Jacques , Enoka Roger M. 
Published: March 2024

AbstractThe aim of our study was to compare the effects of two different plyometric training programs (targeting knee extensors or plantar flexors) on jump height and strength of leg muscles. Twenty‐nine male basketball players were assigned to the knee‐flexed (KF), knee‐extended (KE), or control groups. In addition to regular training, the KF group performed plyometric jumps (10 sets of 10 jumps, 3 sessions/week, 4 weeks) from 50 cm boxes with the knee flexed (90°–120°), whereas the KE group performed the jumps from 30 cm boxes with the knee much more extended (130°–170°). Jumping ability was evaluated with squat jumps (SJs), countermovement jumps (CMJs), and drop jumps from 20 cm (DJ20) and 40 cm (DJ40). Knee and ankle muscles were assessed during maximal isokinetic and isometric tests, and EMG activity was recorded from vastus lateralis and medial gastrocnemius. The KF group increased SJ (+10%, d = 0.86) and CMJ (+11%, d = 0.70) but decreased DJ40 height (−7%, d = −0.40). Conversely, the KE group increased DJ20 (+10%, d = 0.74) and DJ40 (+12%, d = 0.77) but decreased SJ height (−4%, d = −0.23). The reactivity index during DJs increased (+10% for DJ20, d = 0.47; +20% for DJ40, d = 0.91) for the KE group but decreased (−10%, d = −0.48) for the KF group during DJ40. Plantar flexor strength increased for the KE group (d = 0.72–1.00) but not for the KF group. Negative transfer across jumps is consistent with the principle of training specificity. Basketball players interested to perform fast rebounds in their training should avoid plyometric jumps with large knee flexions and long contact times.
Ostracism negatively impacts working self‐perceptions of personality
Authors: Wirth James H. , Hales Andrew H. , Buelow Melissa T. 
Published: March 2024

AbstractWe examined if being ostracized (excluded and ignored) changes working self‐perception of personality ─ a core aspect of the self ─ which may contribute to understanding post‐ostracism behaviour. Across three studies (N = 943), using a virtual ball‐toss game (i.e., Cyberball), participants were either ostracized, included or mentally visualized playing the game. Subsequently, participants reported working self‐perceptions of their personality (using two measures of Big Five personality), ostracism's immediate effects (e.g., basic needs) and post‐ostracism behavioural intentions: aggressive temptations and solitude seeking. Across the studies, ostracism in Cyberball negatively impacted working self‐perception of personality: ostracized participants were less conscientious, agreeable, open and extraverted, and more neurotic (negative emotionality), compared to controls. Illustrating that altered working self‐perceptions are important to consider, ostracism's increase of aggressive temptations was mediated by agreeableness, even when accounting for ostracism's immediate (reflexive) effects. Additionally, ostracism's increase in solitude seeking was mediated by extraversion. Ultimately, these aversive self‐perceptions may create difficulties in socially connecting with others.
Inter‐ and intra‐annual fluctuations and attribution analysis of runoff and sediment transport in the middle and lower Yangtze River
Authors: Yu Yang , Du Sen , Li Min , Zhao Rui , Mou Qin , Min Xuefeng , Xu Wenjie 
Published: March 2024

AbstractAssessing the changing regimes of runoff and sediment load in rivers, as well as analysing their underlying causes, is essential for maintaining the ecological integrity of rivers and promoting the sustainable development of water resources. Current methods of attribution analysis focus on accounting for the effects of climate change and human activities on inter‐annual variability in streamflow and sediment. However, the contribution of individual drivers to intra‐annual hydrologic variability is often overlooked. The study analysed the inter‐ and intra‐annual fluctuations in runoff and sediment load in the middle and lower Yangtze River using a water‐sediment variation attribution model, the Extreme Gradient Boosting algorithm, and the Multiple‐Factor Attribution method. The results showed that human activities were responsible for over 70% of the inter‐ and intra‐annual fluctuation in runoff and sediment load in the Yichang, Hankou, and Datong sections. Additionally, it was found that human activities were the main contributor to the reduction in both runoff and sediment load in all sections. Closer to the Yangtze estuary, human influence on intra‐annual fluctuation of runoff decreases while climate change influence increases, and human influence on both inter‐ and intra‐annual fluctuation of sediment load becomes less significant. The sensitivity of annual runoff to precipitation is greater than that of air temperature and evaporation in the Yichang, Hankou, and Datong sections. An increase of 10% in precipitation from baseline values leads to a corresponding increase of 3.13%, 2.24%, and 3.91% in runoff for the Yichang, Hankou, and Datong sections. The annual sediment load is more sensitive to changes in runoff than to precipitation, air temperature, and evaporation in each section. A 10% increase in runoff from the baseline value leads to an annual sediment load increase of 20.36%, 10.11%, and 8.78% at Yichang, Hankou, and Datong, respectively. This study provides a theoretical basis and guidance for decision‐making to protect and sustainably develop the water and sediment resources in the Yangtze River Basin.
Non‐Canonical Amino Acids for Engineering Peptides and Proteins with new Functions
Authors: Zhou Kelly Zhi Qi , Obexer Richard 
Published: March 2024

AbstractThe universal genetic code, which specifies the 20 standard amino acids (AAs), forms the basis for all natural proteins. Researchers have developed efficient and robust in vivo and in vitro strategies to overcome the constraints of the genetic code to expand the repertoire of AA building blocks that can be ribosomally incorporated into proteins. This review summarizes the development of these in vivo and in vitro systems and their subsequent use for engineering of peptides and proteins with new functions. In vivo genetic code expansion employing engineered othogonal tRNA/aaRS pairs has led to the development of proteins that selectively bind small molecules, cleave nucleic acids and catalyze non‐natural chemical transformations. In vitro genetic code reprogramming using Flexizymes coupled with mRNA display has resulted in potent macrocyclic peptides that selectively bind to therapeutically important proteins. Through these examples, we hope to illustrate how genetic code expansion and reprogramming, especially when coupled with directed evolution or in vitro selection techniques, have emerged as powerful tools for expanding the functional capabilities of peptides and proteins.
Differences in the system accuracy acceptability of four types of blood glucose monitoring systems against five different standards
Authors: Wang Tengjiao , Zhang Lina , Gong Lijun , Xin Yangmei , Han Liang , Li Na , Peng Peng , Zhao Xiuying , Li Runqing 
Published: March 2024

AbstractObjectiveThis study aimed to evaluate the system accuracy of four types of blood glucose monitoring systems (BGMSs) and explore the differences in the system accuracy acceptability of each BGMS against five different standards.MethodsThe glucose measurement values obtained from four types of BGMSs (Roche Accu‐Chek® Performa, Bayer Contour™ TS, Sinomedisite Glupad® H1 Plus, and Sinocare® Gold‐Accu) were evaluated against the reference values obtained from the biochemical analyzer of the central laboratory. The system accuracy acceptability of each BGMS was determined using the criteria specified in five standards, namely the International Organization for Standardization (ISO) 15197:2003, Clinical Laboratory Standards Institute (CLSI) POCT12‐A3, ISO 15197:2013, Chinese Society of Laboratory Medicine (CSLM) consensus, and US Food and Drug Administration (FDA) guidelines.ResultsFrom 2018 to 2022, 10,980 pairs of measurement values were obtained from 366 glucose meters of four types of BGMSs. Significant correlations were observed between the glucose measurement values from the BGMSs and the reference values from the biochemical analyzer of the central laboratory. The correlation coefficient r was 0.995 for Roche Accu‐Chek® Performa, 0.994 for Bayer Contour™ TS, 0.983 for Sinomedisite Glupad® H1 Plus, and 0.997 for Sinocare® Gold‐Accu. The acceptability criteria specified in ISO 15197:2003 were met by 100.00% (135/135) of the glucose meters of Roche Accu‐Chek® Performa, 100.00% (109/109) of Bayer Contour™ TS, 81.61% (71/87) of Sinomedisite Glupad® H1 Plus, and 100.00% (35/35) of Sinocare® Gold‐Accu. Whereas, the acceptability criteria specified in ISO 15197:2013 were met by 99.26% (134/135) of the glucose meters of Roche Accu‐Chek® Performa, 88.07% (96/109) of Bayer Contour™ TS, 58.62% (51/87) of Sinomedisite Glupad® H1 Plus, and 91.43% (32/35) of Sinocare® Gold‐Accu.ConclusionsAmong the four types of BGMSs evaluated, the glucose meters of Roche Accu‐Chek® Performa exhibited superior system accuracy. The system accuracy acceptability of each BGMS varied significantly against the acceptability criteria specified in the five different standards.
Exploring optimal straw mulch thickness during freeze–thaw periods in the central Yellow River basin: Field observations and numerical modelling
Authors: Xue Jing , Lin Jiangtong , Chen Junfeng , Cui Lihong , Zheng Xiuqing 
Published: March 2024

AbstractStraw mulch has been widely used to inhibit soil evaporation in semi‐arid regions, but little attention has been given to exploring optimal straw mulch thicknesses for suppressing soil evaporation under different meteorological conditions in seasonally frozen soil regions. By combining field observations and numerical modelling, the optimal straw mulch thickness for inhibiting soil evaporation under different meteorological conditions was determined. Field experiments indicated that the cumulative soil evaporation associated with straw mulch thicknesses of 1–3 cm was 40%, 53% and 65% lower than that of bare land during freeze–thaw cycles. Compared with that of bare fields, the cumulative soil evaporation simulated by SHAW (simultaneous heat and water) decreased from 9% to 82% and from 36% to 88% during the 2017–2018 and 2018–2019 periods, respectively, when the straw mulch thickness ranged from 1 to 20 cm. The cumulative soil evaporation tended to stabilize until the straw mulch thickness reached 14.3 cm under weather conditions with low humidity, high wind speed and sunshine and 14.5 cm under weather conditions with high or moderate humidity, low or moderate wind speed and sunshine from 1987 to 2017. The results have implications for reducing nonproductive soil evaporation and improving agricultural water management in seasonally frozen regions.
Optical method supported by machine learning for dynamics of C‐reactive protein concentrations changes detection in biological matrix samples
Authors: Sokołowski Patryk , Cierpiak Kacper , Szczerska Małgorzata , Wróbel Maciej , Łuczkiewicz Aneta , Fudala‐Książek Sylwia , Wityk Paweł 
Published: March 2024

AbstractIn this article we present the novel spectroscopy method supported with machine learning for real‐time detection of infectious agents in wastewater. In the case of infectious diseases, wastewater monitoring can be used to detect the presence of inflammation biomarkers, such as the proposed C‐reactive protein, for monitoring inflammatory conditions and mass screening during epidemics for early detection in communities of concern, such as hospitals, schools, and so on. The proposed spectroscopy method supported with machine learning for real‐time detection of infectious agents will eliminate the need for time‐consuming processes, which contribute to reducing costs. The spectra in range 220–750 nm were used for the study. We achieve accuracy of our prediction model up to 68% with using only absorption spectrophotometer and machine learning. The use of such a set makes the method universal, due to the possibility of using many different detectors.
CD93 regulates breast cancer growth and vasculogenic mimicry through the PI3K/AKT/SP2 signaling pathway activated by integrin β1
Authors: Liu Hong , Zhang Jianhui , Zhao Yanjun , Fan Zhixiong , Yang Yongheng , Mao Yuanyuan , Yang Jingyuan , Ma Shungao 
Published: March 2024

AbstractIn women, breast cancer (BC) accounts for 7%–10% of all cancer cases and is one of the most common cancers. To identify a new method for treating BC, the role of CD93 and its underlying mechanism were explored. MDA‐MB‐231 cells were used in this study and transfected with si‐CD93, si‐MMRN2, oe‐CD93, si‐integrin β1, or oe‐SP2 lentivirus. After MDA‐MB‐231 cells were transfected with si‐NC or si‐CD93, they were injected into nude mice by subcutaneous injection at a dose of 5 × 106/mouse to construct a BC animal model. The expression of genes and proteins and cell migration, invasion and vasculogenic mimicry were detected by RT‒qPCR, western blot, immunohistochemistry, immunofluorescence, Transwell, and angiogenesis assays. In pathological samples and BC cell lines, CD93 was highly expressed. Functionally, CD93 promoted the proliferation, migration, and vasculogenic mimicry of MDA‐MB‐231 cells. Moreover, CD93 interacts with MMRN2 and integrin β1. Knockdown of CD93 and MMRN2 can inhibit the activation of integrin β1, thereby inhibiting the PI3K/AKT/SP2 signaling pathway and inhibiting BC growth and vasculogenic mimicry. In conclusion, the binding of CD93 to MMRN2 can activate integrin β1, thereby activating the PI3K/AKT/SP2 signaling pathway and subsequently promoting BC growth and vasculogenic mimicry.
Perceived political corruption and tax compliance intentions among private enterprises in emerging economies: The roles of tax morale and tax tolerance in Ghana
Authors: Agbanyo Richard , Musah Godwin , Doku James Ntiamoah , Quarshie Joseph , Dery Nyuregbee Yahbewobr 
Published: March 2024

AbstractCorruption has been identified as a major debilitating factor in tax revenue generation, especially in developing countries. This study examines the effects of perceived political corruption on tax compliance intention and investigates the mediating roles of tax morale and tax tolerance among private businesses in Ghana. Data were collected with a questionnaire from 1133 private firms randomly sampled in the Greater Accra Region. Estimation was done using structural equation modelling with maximum likelihood estimation techniques. The study finds that perceived political corruption diminishes tax morale, tolerance and compliance intentions. Moreover, tax tolerance and tax morale enhance compliance intentions. Again, tax morale and tax tolerance partially mediate the relationship between perceived political corruption and tax compliance intention, reducing corruption's negative effects on intentions to comply with tax obligations. Finally, these tax compliance behaviours vary with education, age of business, sectors and firm size. The government of Ghana needs to focus on voluntary tax compliance by convincingly fighting corruption, especially by tightening fiscal loopholes.
Optimization of a DNA‐launched SARS‐CoV‐2 replicon with RNA splicing inhibitor Isoginkgetin
Authors: Zhang Hu , Guo Haitao 
Published: March 2024

AbstractWe have previously developed a bacterial artificial chromosome (BAC)‐vectored SARS‐CoV‐2 replicon, namely BAC‐CoV2‐Rep, which, upon transfection into host cells, serves as a transcription template for SARS‐CoV‐2 replicon mRNA to initiate replicon replication and produce nanoluciferase (Nluc) reporter from the subgenomic viral mRNA. However, an inherent issue of such DNA‐launched replicon system is that the nascent full‐length replicon transcript undergoes process by host RNA splicing machinery, which reduces replicon replication and generates spliced mRNA species expressing NLuc reporter independent of replicon replication. To mitigate this problem, we employed Isoginkgetin, a universal eukaryotic host splicing inhibitor, to treat cells transfected with BAC‐CoV2‐Rep. Isoginkgetin effectively increased the level of full‐length replicon transcripts while concurrently reducing the level of Nluc signal derived from spliced replicon mRNA, making the Nluc reporter signal more correlated with replicon replication, as evidenced by treatment with known SARS‐CoV‐2 replication inhibitors including Remdesivir, GC376, and EIDD‐1931. Thus, our study emphasizes that host RNA splicing is a confounding factor for DNA‐launched SARS‐CoV‐2 replicon systems, which can be mitigated by Isoginkgetin treatment.
A paradox theory lens on proactivity, individual ambidexterity, and creativity: An empirical look
Authors: Wang Jie , Kim Tae‐Yeol , Bateman Thomas S. , Jiang Yuan , Tang Guiyao 
Published: March 2024

SummaryParadox theory suggests that contradictory demands, like applying current work methods while exploring new ones, should be viewed as dualities with competing and complementary aspects. It advocates for employee ambidexterity, where employees must manage exploitation and exploration. We know little about how personal dispositions affect ambidexterity independently or when interacting with situational factors. Based on a time‐lagged survey of 364 employee–supervisor pairs from 74 R&D teams, we found that proactive disposition was positively related to ambidexterity, enhancing creativity. Guided by trait activation theory, we found further that paradoxical supervision and job autonomy enhanced the relationship between proactive disposition and employee ambidexterity and the indirect effect of proactive disposition on creativity via ambidexterity. We discuss these findings' theoretical and practical implications, extending the literature on proactivity, ambidexterity, and paradox theory.
Trends in the ocean mixed‐layer depth in the western North Pacific tropical cyclone basin
Authors: Wu Liqin , Feng Xiaofang , Wu Liguang 
Published: March 2024

AbstractThe upper ocean mixed‐layer depth (MLD) has been recognized as a crucial factor in understanding the impact of climate change on tropical cyclone (TC) intensity, while the specific MLD variations in the western North Pacific (WNP) basin have received comparatively little attention. Using two ocean reanalysis datasets and the output of 28 CMIP6 models, the climatological mean MLD and its trend in the TC active region are examined. Compared to the ORAS4 and EN4 datasets, the spatial pattern of the climatological mean MLD can be well simulated in the multi‐model ensemble (MME). The mean MLD decreases with increasing latitude and maintains the maximum in the equatorial region. The spatial patterns of MLD long‐term (1958–2017) and short‐term (1979–2017) trends are deepening in the TC active region, with the relatively large positive trends occurring to the southeastern WNP primarily between 5°N and 15°N. However, the simulated trend in the MME is dominant with shoaling MLD, and the shoaling of the MLD is also projected under the SSP5‐8.5 scenario. It is suggested that the bias on the simulated shoaling of the MLD in CMIP6 models may result from the overestimated enhancement of the upper‐ocean stratification. Thus, there is a discrepancy between the observed and simulated MLD trends in the WNP basin, which may have implications for TC intensity change under global warming scenarios.