bluuebunny/crossref_metadata_2025_split huggingface dataset:
Ringing in the Ears: Approaches to Imaging and Management of Tinnitus
Authors: Abou Shaar Bader , Qureshy Kaiser , Almalki Youssef , Khan Nazir 
Published: March 2024

ABSTRACT
Tinnitus is a condition in which patients perceive sound without an external stimulus. It can be classified into either pulsatile or nonpulsatile tinnitus. This condition affects around 14% of the global population, and the severity of tinnitus can range from barely noticeable to devastating. In most cases, tinnitus is benign and nonpulsatile in nature. The diagnostic role of imaging is to detect treatable and specific pathology. Therefore, a comprehensive clinical assessment, which includes a meticulous examination for associated symptoms like hearing loss, vertigo, or headaches, along with a thorough physical examination, otoscopy, and audiologic testing, is imperative before considering any imaging studies as the choice of imaging will depend on various factors. Nonpulsatile or continuous tinnitus is most commonly associated with presbycusis but can also be caused by functional injuries due to ototoxic medications or exposure to loud noise and usually requires no imaging evaluation. Unlike nonpulsatile tinnitus, imaging patients with pulsatile tinnitus typically reveals perceptible findings. The cause of pulsatile tinnitus is usually a vascular tumor, vascular malformation, or vascular anomaly. Other causes of tinnitus include idiopathic intracranial hypertension, otosclerosis, Paget’s disease, and Meniere’s disease. One of the main challenges is that the underlying cause of tinnitus is often unknown. Another challenge is that tinnitus can have a significant effect on a person’s quality of life, yet the condition is not life-threatening and there is no cure. We present a clinical review of the most prevalent causes of tinnitus along with an emphasis on the diagnostic imaging workup and management of common presentations.
Hospital complications in patients with acute kidney injury after coronary artery bypass grafting
Authors: Arutyunyan L. A. , Kremneva L. V. , Gapon L. I. , Shalaev S. V. 
Published: March 2024

The aim was to assess the incidence of hospital complications in patients with acute kidney injury (AKI) after coronary artery bypass grafting (CABG).Patients and Methods. The study included 77 patients with stable angina who underwent CABG, aged 65 (61-69) years, 77,9 % men. The number of patients with arterial hypertension was 96,1 %, with carbohydrate metabolism disorders 45,5 %, with chronic kidney disease (CKD) 22,1 %, and with myocardial infarction (MI) 57,1 %. CABG on the working heart was performed in 28,6 %, bimammary CABG in 49,4 %. The duration of artificial circulation was 64 (55-82) minutes; the number of shunts implanted was 2,7+0,7 units. CKD was diagnosed when the glomerular filtration rate was less than 60 ml/min. The development of AKI was assessed according to the KDIGO criteria (2012).Results. CABG related AKI was detected in 10 (13 %) patients, of which grade 1 in 9 (11,7 %), grade 2 in 1 (1,3 %). The indicators associated with AKI after CABG were more severe initial CKD (stages 3b and 4 CKD – 20 % vs 1,5 %, p=0,043), a higher incidence of acute heart failure (in terms of adrenaline requirement – 30 % vs 5,9 %, p=0,043), more occluded coronary arteries (in the groups with and without CABG: one occlusion 70 % and 52,2 %, two occlusions 0 % and 13,4 %, three occlusions 10 % and 0 %, respectively, p=0,028). More severe CKD (stages 3b and 4) statistically significantly increased the relative risk of AKI after CABG by an average of 2,9 times. Among patients with AKI compared to patients without AKI after CABG, there was a higher incidence of cardiac death (20 % vs 0 %, p=0,015), intraoperative MI (60 % vs 8,9 %, p=0,001), acute heart failure (30 % vs 5,9 %, p=0,043).Conclusion. The incidence of AKI following CABG was 13 %. The development of AKI was associated with more severe initial CKD. Patients with postoperative AKI had a poor hospital prognosis.
Effect of renal replacement therapy on glycaemic variability and indices of carbohydrate metabolism in patients with diabetes mellitus
Authors: Markova T. N. , Yavorskaya V. O. , Ushakova A. I. , Berdinsky V. A. , Ibragimova T. V. , Kumakhova L. A. , Orlova A. D. , Markov A. D. , Usatiuk S. S. 
Published: March 2024

Background. Patients with diabetes mellitus (DM) on renal replacement therapy (RRT) have high glycaemia variability (GV), the severity of which may depend on the dialysis method.The aim: To study GV in patients with type 1 diabetes and type 2 diabetes (on baseline-bolus insulin therapy) receiving RRT with programmed hemodialysis (PHD) and continuous ambulatory peritoneal dialysis (CAPD).Patients and Methods: Twenty-seven patients with terminal chronic renal failure and DM receiving RRT from July 2022 to March 2023 were studied. Patients underwent flash glucose monitoring (FGM) using FreeStyle Librе portable system with further evaluation of GV parameters and indices, median days of measurement – 14.Results. In the total group, 7 patients (23,3 %) had TIR > 70 %, mean TIR value was 56,3 %±22,0 %, 66,7 % of patients had CV > 36 %, mean CV value was 38,5 %±9,6 %. All indices of GV (MAGE, LBGI, HBGI, M-value, J-index, Conga, LI) exceeded the reference values. When comparing GV indices in patients on PHD and CAPD, it was revealed that LBGI in PHD group was 10,1±5,71 vs CAPD – 5,58±4,22, p=0,025. The critical point of glucose reduction on PHD was the fourth hour from the beginning of the procedure (57.1 % of patients had glycemia < 3.9 mmol/l). Higher median glucose values were found in the first three days of FGM compared to the last three days in both PHD group (p=0.002) and CAPD group (p=0.022).Conclusions. Patients with diabetes on RRT have high GV, low percentage of achieving TIR due to high risk of hypoglycemic conditions in patients on PHD. The critical point of glycaemia reduction is fourth hour after the start of the PHD session. Patients on CAPD have a lower risk of hypoglycemia. FGM improves glycaemic control.
Condition of the cardiovascular system in Wistar rats with experimental renal dysfunction
Authors: Beresneva O. N. , Parastaeva M. M. , Ivanova G. T. , Ivanova A. N. , Ognev O. G. , Kucher A. G. 
Published: March 2024

The aim: to evaluate functional and structural changes in blood vessels and myocardium in Wistar rats at different stages of the formation of experimental kidney dysfunction.Materials and Methods. Four groups of animals were studied. The first two groups consisted of rats subjected to 5/6 nephrectomy (NE). The period after NE is 2 or 4 months. The third and fourth groups included sham-operated (SO) animals of a similar observation period. After the end of the experiment, blood pressure was measured in rats, the left ventricular mass index (LVMI) was calculated, a biochemical blood test, histological, immunohistochemical and electron microscopic examination of the myocardium were performed, and the contractile activity of the portal vein was recorded for a period of 2 months (in vitro).Results. 2 months after NE, an increase in blood pressure, LVMI, and a decrease in the autorhythmic contractile activity of the portal vein were detected in rats. At the histological level, thickening of cardiomyocytes and arterial vessel walls and the presence of perivascular fibrosis were noted. After 4 months, in rats with NE, the increase in blood pressure, cardiomyocyte hypertrophy and perivascular fibrosis progressed. The thickness of cardiomyocytes was 14.1±3.11 μm, which was significantly greater than in the group with NE for 2 months (12.5±1.5 μm; p=0.008). At this period of observation, electron microscopic examination revealed deintegration of myofibrils, disruption of myofibril stacking and z-disk structure, and changes in the shape of mitochondria. 2 months after NE, an increase in the area of open capillaries was detected in rats (1902.8±202.9 μm²) compared to the corresponding LO animals (730.4±58.2 μm²; p=0.000). As renal dysfunction develops, the capillary area tends to increase (2139.1±396.5 μm²; p =0.120).Conclusion. In Wistar rats with renal dysfunction, changes were detected not only in the level of blood pressure, but also in the functional activity of the intravenous fluid, as well as in the structural components of the myocardium – cardiomyocytes, stroma and blood vessels. The increase in myocardial mass at the histological level was manifested by a significant increase in the thickness of cardiomyocytes, the volume of connective tissue, and the thickness of the wall of arterial vessels, reaching a maximum value at a longer period after NE.
A sustentabilidade no Curso de Ensino Médio Integrado, técnico em Química, do Instituto Federal de Santa Catarina
Authors: Netto Daiane , Luna Tarusa , Sentinelo Jaqueline Tondato 
Published: March 2024

A relação recente entre ser humano-sociedade-natureza é caracterizada pelo uso excessivo dos recursos naturais. A pedagogia e o currículo podem ser estratégicos para tornar o desenvolvimento mais sustentável. Assim, o curso Técnico Integrado de Química, associado a temas transversais, é essencial para a compreensão dos processos químicos no ambiente e das consequências da ação humana na natureza. Este trabalho objetivou analisar o Projeto Pedagógico do Curso Técnico Integrado em Química do Instituto Federal de Santa Catarina, Florianópolis (IFSC), em relação à sustentabilidade. Utilizou-se a Pesquisa Documental (FONSECA, 2002) e a Análise de Conteúdo (BARDIN, 1977). Devido à pandemia da Covid-19, não foi possível a realização de entrevistas. A hipótese é que o curso apresenta a sustentabilidade de forma superficial e associada à ideia de causar menos impacto na sociedade de consumo, não alinhado à perspectiva de sustentabilidade considerada pelas autoras, que envolve a preservação da biodiversidade. Embora o termo “sustentabilidade” não tenha sido mencionado no PPC (Projeto Pedagógico do Curso), os demais resultados mostram que ela está presente no currículo do curso. Reforça-se a importância de dedicar esforços à Educação Continuada para formar o corpo docente em questões ambientais, uma vez que esse profissional é importante ator de mudança
Convergências e divergências entre o ensino de Matemática na Licenciatura em Pedagogia e nos anos iniciais do Ensino Fundamental
Authors: Matos Diego De Vargas , Lara Isabel Cristina Machado de 
Published: March 2024

Este artigo apresenta dados parciais de uma dissertação de mestrado sobre formação do professor que ensina Matemática nos anos iniciais. Delimita-se ao objetivo específico de analisar convergências e divergências entre conhecimentos matemáticos adquiridos em cursos de Licenciatura em Pedagogia e aqueles desenvolvidos na prática por professores dos anos iniciais do Ensino Fundamental. Metodologicamente, realiza uma Análise Textual Discursiva de respostas dadas a um questionário respondido por dez professoras dos anos iniciais que lecionam em escolas públicas de Porto Alegre, RS. Partindo de três categorias a priori sobre conhecimentos docentes, sejam elas: conhecimento do conteúdo; conhecimento pedagógico do conteúdo; e, conhecimento curricular, emergiram 14 subcategorias sobre os conhecimentos matemáticos adquiridos em cursos de Pedagogia e aqueles desenvolvidos na prática pelas professoras dos anos iniciais participantes. A análise evidencia que professores dos anos iniciais desenvolvem em sua prática mais conhecimentos de conteúdo relacionados à Matemática do que adquirem em sua formação inicial. Ainda, modificam, durante o ensino de Matemática nos anos iniciais, conhecimentos pedagógicos e conhecimentos curriculares adquiridos nos cursos de Licenciatura em Pedagogia.
Pemberdayaan Masyarakat Melalui Motivasi Kewirausahaan Bioskop 3D Di Desa Pager Kecamatan Bungkal Kabupaten Ponorogo
Authors: Yuwono Amrih , Subagyo Anton , Fauzi Ferry , Heriana Tutik , Setyaningrum Diyah , Mufidah Alfy Rizki 
Published: March 2024

Desa Pager Kecamatan Bungkal Kabupaten Ponorogo sebagai Mitra pengabdian memiliki potensi wisata alam, diantaranya adalah Taman Wisata Sendang Bulus, dan keberadaannya merupakan desa binaan Kemenparekraf RI. BUMDes selaku pengelola Taman Wisata Sendang Bulus setelah melakukan pembenahan kolam, paseban, Mushola, kamar Mandi dan toilet dan yang terbaru telah dibuka wahana "kolam renang anak" di lokasi wisata Sendang Bulus. Permasalahan mitra adalah pengembangan wahana yang seperti apakah yang bisa menambah kunjungan wisatawan, sekaligus memberi manfaat ekonomis dan sosial bagi lingkungan. Masih belum ada kesepahaman antara pemangku kepentingan tentang wahana baru yang menarik dengan biaya terjangkau, mempunyai nilai ekonomis dan mempunyai potensi pasar. Metode pendekatan pengabdian yang digunakan adalah dengan observasi, penyuluhan, diskusi dan simulasi melalui peragaan kegiatan. Hasil pelaksanaan dan capaian kegiatan adalah 1) Terwujudnya penyuluhan dan simulasi dengan peragaan Bioskop 3D 2) Terwujudnya rekomendasi kepada pemangku kepentingan setempat (Kepala Desa, BUMDes dan Pokdarwis, SDN Pager, karang taruna) tentang wahana Bioskop 3 Dimensi dengan naskah PPT Studi Kelayakan Usaha.
Intraoperative Sonographically Guided Resection of Non-Enhancing Diffuse Gliomas: Study Protocol for a Randomised, Controlled Trial
Authors: Дмитриев Александр Юрьевич , Дашьян Владимир Григорьевич , Природов Александр Владиславович , Хамидова Лайла Тимарбековна 
Published: March 2024

Введение. Преимущества интраоперационной сонографии в хирургии глиом, не накапливающих контрастный препарат при магнитно-резонансной томографии, — возможность оценки опухоли в режиме реального времени, многократность сканирования, отсутствие противопоказаний и низкая стоимость оборудования. В настоящий момент все работы о целесообразности применения сонографии при удалении таких опухолей имеют невысокую доказательную силу.
Методы. Это рандомизированное одноцентровое исследование на превосходство со слепой оценкой исходов у 96 больных с двумя группами и распределением участников 1:1. Первичный исход — радикальность резекции глиомы (в процентах). Гипотеза исследования — применение интраоперационной сонографии повышает радикальность удаления глиом, не накапливающих контрастный препарат. Предусмотрена блоковая стратифицированная рандомизация, критерием стратификации является расположение глиомы рядом с двигательной или речевой зоной головного мозга. В исследование будут включены впервые выявленные одиночные супратенториальные глиомы, не накапливающие контрастный препарат при магнитно-резонансной томографии, у пациентов 18-79 лет, оцененных в 60-100 % по шкале Карновского. У участников основной группы будет применена сонография для интраоперационной оценки радикальности удаления опухоли. В контрольной группе глиома будет удалена только под контролем зрения. Интраоперационная магнитно-резонансная томография и флуоресценция использованы не будут.
Выводы. Подтверждение гипотезы исследования позволит более широко внедрить интраоперационную сонографию в хирургии глиом головного мозга, не накапливающих контрастный препарат, и увеличить радикальность их резекции.
Регистрация исследования. Исследование зарегистрировано в реестре ClinicalTrials.gov под номером NCT05470374 (SONOGLIO).
Platinum Resistance after Neoadjuvant Chemotherapy
Authors: Городнова Татьяна Васильевна , Соколенко Анна Петровна , Котив Христина Богдановна , Иванцов Александр Олегович , Кондратьев Сергей Валерьевич , Берлев Игорь Викторович , Имянитов Евгений Наумович 
Published: March 2024

Введение. В BRCA1-ассоциированных карциномах яичника резистентность к платине может возникать уже в процессе неоадъювантной химиотерапии за счет селекции и репопуляции клеток с восстановленной или частичной сохранной функцией репарации ДНК. Применение бесплатиновой адъювантной химиотерапии (АХТ) у больных без потери гетерозиготности BRCA1 в остаточной опухоли (noLOH) может улучшить результаты комбинированного лечения больных распространенным раком яичника. Цель — в рамках проспективного рандомизированного исследования NCT04747717 проанализировать результаты использования бесплатиновой АХТ по схеме «доксорубицин и паклитаксел» (АТ) у больных без потери гетерозиготности BRCA1 в остаточной опухоли.
Материалы и методы. Проспективное клиническое испытание NCT04747717 включает 22 пациентки из группы «митомицин С и цисплатин» (MP) и 15 больных, рандомизированных в группу стандартной терапии «паклитаксел и карбоплатин» (TCbP). Две пациентки из группы MP в адъювантном режиме получили комбинацию АТ.
Результаты. В группе МР у 5/18 (28 %) пациенток в резидуальной опухолевой ткани обнаружено восстановление гетерозиготности BRCA1, тогда как в группе TCbP статус BRCA1 noLOH наблюдался у 3/10 (30 %) больных. Обе пациентки, которые в адъювантном режиме получали бесплатиновую схему AT, на момент оценки результатов находятся в клинической ремиссии продолжительностью 41 и 17 месяцев.
Заключение. Смена химиотерапии в послеоперационном периоде на бесплатиновые режимы у пациенток с изменением статуса LOH является перспективным подходом терапии BRCA1-ассоциированных карцином яичника.
Comparative Analysis of Smartphones and Survey-Grade GNSS Receivers for Parcel Boundary Determination
Authors: Oluwadare Caleb , Salami Mary 
Published: March 2024

This paper advances the existing body of knowledge on the suitability of the accuracy derivable from the use of smartphones for cadastral mapping. Zenvus App software was installed on two smartphones of a different make. A set of dual-frequency GPS Promark 3 receivers and two different smartphones of different makes were used for data acquisition. Observations were carried out at the boundaries of ten parcels of land, comprising 46 boundary points. The coordinates of these points were obtained using Differential Global Positioning System (DGPS) observation in static mode and two Android smartphones (the Samsung A70 and the Tecno Spark 3 Pro). Mean score, root mean square error, and one-way analysis of variance were used to show significant differences in the equipment used. Overall, both the accuracy (mean) and precision (RMSE) were lower than those obtained by Differential GPS. A one-way analysis of variance (ANOVA) was calculated on the values of both X and Y. For X, the analysis was not significant; F (1, 45) = 0.88, p = 0.419 and for Y, the analysis was also not significant; F (1, 45) = 0.97, p = 0.383. The total RMSE shows that the coordinates of points as obtained by the Samsung smartphone (3.368) were more precise than those obtained by Tecno (4.041). However, the two smartphones (Tecno and Samsung) were less accurate than differential GPS. This implies that there is a 95% chance that the errors in the estimates are less than 6.993m (for Tecno) and 5.848m (for Samsung), respectively. The variation in the observations obtainable with smartphones affects both linear and polygon estimates. The study concluded that the magnitude of these errors is significant in cadastral survey practices and hence not suitable for use. It is recommended that further studies be carried out on the use of the Zenvus app on centimeter grade smartphones; probably this could yield a better result suitable for cadastral mapping.
Modeling the Radial Distribution of Pulsars in the Galaxy
Authors: Xie J. T. , Wang J. B. , Wang N. , Manchester R. , Hobbs G. 
Published: March 2024

Abstract
The Parkes 20 cm multibeam pulsar surveys have discovered nearly half of the known pulsars and revealed many distant pulsars with high dispersion measures. Using a sample of 1301 pulsars from these surveys, we have explored the spatial distribution and birth rate of normal pulsars. The pulsar distances used to calculate the pulsar surface density are estimated from the YMW16 electron-density model. When estimating the impact of the Galactic background radiation on our survey, we projected pulsars in the galaxy onto the Galactic plane, assuming that the flux density distribution of pulsars is uniform in all directions, and utilized the most up-to-date background temperature map. We also used an up-to-date version of the ATNF Pulsar Catalogue to model the distribution of pulsar flux densities at 1400 MHz. We derive an improved radial distribution for the pulsar surface density projected onto the Galactic plane, which has a maximum value at ∼4 kpc from the Galactic center. We also derive the local surface density and birth rate of pulsars, obtaining 47 ± 5 kpc−2 and ∼4.7 ± 0.5 kpc−2 Myr−1, respectively. For the total number of potentially detectable pulsars in the galaxy, we obtain (1.1 ± 0.2) × 104 and (1.1 ± 0.2)×105 before and after applying the Tauris & Manchester beaming correction model. The radial distribution function is used to estimate the proportion of pulsars in each spiral arm and the Galactic center.
Antisémitisme et société française
Authors: Mayer Nonna , Euvé François , Sarthou-Lajus Nathalie 
Published: March 2024

Depuis l’attaque du 7 octobre 2023, on assiste à une forte progression des actes antisémites en France. Pour comprendre ce phénomène, il faut le resituer sur une longue période. Les enquêtes montrent que, dans l’ensemble, le racisme serait plutôt en régression. L’« autre » est mieux accepté. Mais l’antisémitisme persiste, ravivé par la situation internationale et, du fait de la permanence de préjugés, différent d’autres formes de racisme.
Spirituality and Recovery From Severe Mental Disorders: A Systematic Review
Authors: Sawab Sawab , Yusuf Ah , Fitryasari Rizky , Arifin Hidayat 
Published: March 2024

Purpose:
The current study investigated the impact of spirituality and mental disorder recovery practices among individuals with severe mental disorders.

Method:
A comprehensive search across six databases—Scopus, ScienceDirect, ProQuest, SpringerLink, PubMed, and CINAHL—was performed to identify relevant articles. A total of 651 articles were screened, and 16 met inclusion criteria.

Results:
Findings revealed that spirituality significantly contributed to the improvement of individuals with severe mental disorders by fostering the development of self-confidence, self-control, strength, and hope, thereby enhancing overall quality of life. In addition, spirituality appeared to correlate with increased self-efficacy.

Conclusion:

Within the mental health recovery framework, spirituality has emerged as a crucial element in facilitating significant life improvements through the exploration of essential motivational strategies. Psychiatric–mental health nurses could play a pivotal role in helping individuals with severe mental disorders by addressing their spiritual needs, thereby promoting holistic recovery and care. [
Journal of Psychosocial Nursing and Mental Health Services, 62
(8), 11–17.]
Stratégies & Droit
Authors: ADDCDA  
Published: March 2024

« La plupart des hommes ont de la poésie une idée si vague, que ce vague même de leur idée est pour eux la définition de la poésie ». Au commencement de notre réflexion, nous étions tentés de transposer ces vers de Paul Valéry à la stratégie.Mais la stratégie est souvent œuvre de l'ombre, conçue de sorte que la lumière puisse n'éclairer qu'une part de la réalité. Elle ne s'annonce pas toujours au grand jour.Parfois, elle se trouve là sans qu'on y prête attention.Notre humble ambition, au travers de ce colloque, est de porter la lumière sur ce qu'est la stratégie et comment elle s'associe avec le droit. De la formulation du sujet au choix des contributions, nous nous sommes efforcés de garder à l'esprit une idée: celle du pluralisme. Nous avons été portés par notre curiosité pour découvrir, au travers des brillant(e)s intervenant(e)s, de nombreux domaines et approches différents. C'est cette curiosité que nous partageons à l'occasion du colloque annuel de l'Association des Doctorants et Docteurs du Centre de Droit des Affaires.La stratégie ressemble quelque peu au droit : elle ne tolère pas d'être absente.Elle entretient avec lui des rapports ambivalents : elle l'utilise, le contourne, s'y heurte.Il fallait percer à jour les relations qu'entretiennent stratégie et droit. À l'évidence, cet enjeu appelait tant des chercheurs que des praticiens de multiples horizons.Nous les remercions d'avoir répondu à notre appel.