bluuebunny/crossref_metadata_2025_split huggingface dataset:
Treatment and outcomes of patients with chronic lung disease and acute myocardial infarction: Insights from the nationwide AMIS plus registry
Authors: Beckmann C. , Foster‐Witassek F. , Brutsche M. , Maeder M. T. , Eberli F. , Roffi M. , Pedrazzini G. , Radovanovic D. , Rickli H. 
Published: March 2024

AbstractBackgroundLimited data are available on patients with chronic lung disease (CLD) presenting with acute myocardial infarction (AMI). We aimed to analyse baseline characteristics, treatment and outcome of those patients enrolled in the Swiss nationwide prospective AMIS Plus registry.MethodsAll AMI patients enrolled between January 2002 and December 2021 with data on CLD, as defined in the Charlson Comorbidity Index, were included. The primary endpoints were in‐hospital mortality and major adverse cardiac and cerebrovascular events (MACCE), defined as all‐cause death, reinfarction and cerebrovascular events. Baseline characteristics, in‐hospital treatments and outcomes were analysed using descriptive statistics and logistic regression.ResultsAmong 53,680 AMI patients enrolled during this time, 5.8% had CLD. Compared with patients without CLD, CLD patients presented more frequently with non‐ST‐elevation myocardial infarction (MI) and type 2 MI (12.8% vs. 6.5%, p < 0.001). With respect to treatment, CLD patients were less likely to receive P2Y12 inhibitors (p < 0.001) and less likely to undergo percutaneous coronary interventions (68.7% vs. 82.5%; p < 0.001). In‐hospital mortality declined in AMI patients with CLD over time (from 12% in 2002 to 7.3% in 2021). Multivariable regression analysis showed that CLD was an independent predictor for MACCE (adjusted OR was 1.28 [95% CI 1.07–1.52], p = 0.006).ConclusionPatients with CLD and AMI were less likely to receive evidence‐based pharmacologic treatments, coronary revascularization and had a higher incidence of MACCE during their hospital stay compared to those without CLD. Over 20 years, in‐hospital mortality was significantly reduced in AMI patients, especially in those with CLD.
The different responses of Batocera horsfieldi adults to Juglans regia bark and leaf volatile compounds
Authors: Xu Danping , Qian Qianqian , Zhuo Zhihang 
Published: March 2024

AbstractBatocera horsfieldi (Hope) (Coleoptera: Cerambycidae) is an important pole borer pest. It causes serious harm to various hosts, particularly Juglans regia L. (Juglandaceae). In this study, headspace solid‐phase microextraction (HS‐SPME), gas chromatography–mass spectrometry (GC–MS), and electroantennogram (EAG) responses were combined to examine the mechanism by which B. horsfieldi adults locate their host, J. regia. The results showed that J. regia contained 65 volatile compounds in all, with 36 and 42 volatile substances in bark and leaves, respectively. Moreover, terpenes accounted for the largest relative content among the volatile compounds of bark and leaves, 43.4 and 78.9%, respectively. Ten of 19 selected volatile components elicited significant EAG responses in adult B. horsfieldi, which indicated that the pest may prefer certain volatile compounds when selecting a host. Sex and volatile concentration affected the responses of B. horsfieldi. Male adults had the strongest EAG responses to 1‐octen‐3‐ol, whereas female adults had the strongest EAG responses to linalool. Host selection in B. horsfieldi was somewhat positively associated with the concentrations of the effective volatile compounds in the host. Furthermore, B. horsfieldi showed varying preferences for isomers. This work provided data support for the development of insect attractants, and laid a theoretical foundation for the ecological protection of local forestry.
Does the temperature–size rule apply to idiobiont parasitoids?
Authors: Gagnon Annie‐Ève , Martel Véronique , Boivin Guy 
Published: March 2024

AbstractIn most ectotherms, several life‐history traits, including body size, respond to environmental conditions through the temperature–size rule (TSR). The mechanisms underlying the TSR are still being debated, but studying idiobiont insect parasitoids, which develop with a fixed amount of resources, may shed light on this relationship. In this study, we conducted experiments to determine how the developmental temperature affects various characteristics of male and female Trichogramma euproctidis (Girault) (Hymenoptera: Trichogrammatidae), an idiobiont egg parasitoid of Lepidoptera. The study tested various hypotheses, including the cellular or oxygen diffusion hypotheses and the resource acquisition hypothesis, to understand whether T. euproctidis follows the TSR. The developmental time of both male and female T. euproctidis decreased with increasing temperature. Both males and females displayed a unimodal distribution for size, dry mass, and lipid content, with individuals at lower and higher temperatures being smaller, weighing less, and containing fewer lipids. Female lifetime fecundity increased from 13 to 24 °C and then decreased at 31 °C. Additionally, the number and size of gametes in male and female T. euproctidis displayed a unimodal distribution with increasing temperature. Trichogramma euproctidis deviates from the TSR as it follows a non‐linear reaction norm with an optimal developmental temperature. This result supports the hypothesis that for species following TSR and having unlimited access to food resources, the resource acquisition hypothesis is a significant mechanism explaining the TSR. With climate change affecting temperature, understanding the TSR is crucial, and research on insect parasitoids may help reveal how the interplay between environmental temperature and resource allocation affects the TSR in natural populations.
Experimentally monitored calcium dynamics at synaptic active zones during neurotransmitter release in neuron–muscle cell cultures
Authors: Sun Xiaoping , Yazejian Bruce , Peskoff Arthur , Grinnell Alan D. 
Published: March 2024

AbstractCa2+‐dependent K+ (BK) channels at varicosities in Xenopus nerve–muscle cell cultures were used to quantify experimentally the instantaneous active zone [Ca2+]AZ resulting from different rates and durations of Ca2+ entry in the absence of extrinsic buffers and correlate this with neurotransmitter release. Ca2+ tail currents produce mean peak [Ca2+]AZ ~ 30 μM; with continued influx, [Ca2+]AZ reaches ~45–60 μM at different rates depending on Ca2+ driving force and duration of influx. Both IBK and release are dependent on Ca2+ microdomains composed of both N‐ and L‐type Ca channels. Domains collapse with a time constant of ~0.6 ms. We have constructed an active zone (AZ) model that approximately fits this data, and depends on incorporation of the high‐capacity, low‐affinity fixed buffer represented by phospholipid charges in the plasma membrane. Our observations suggest that in this preparation, (1) some BK channels, but few if any of the Ca2+ sensors that trigger release, are located within Ca2+ nanodomains while a large fraction of both are located far enough from Ca channels to be blockable by EGTA, (2) the IBK is more sensitive than the excitatory postsynaptic current (EPSC) to [Ca2+]AZ (K1/2–26 μM vs. ~36 μM [Ca2+]AZ); (3) with increasing [Ca2+]AZ, the IBK grows with a Hill coefficient of 2.5, the EPSC with a coefficient of 3.9; (4) release is dependent on the highest [Ca2+] achieved, independent of the time to reach it; (5) the varicosity synapses differ from mature frog nmjs in significant ways; and (6) BK channels are useful reporters of local [Ca2+]AZ.
Effectiveness of coral (Bilbunna) relocation as a mitigation strategy for pipeline construction at Hayman Island, Great Barrier Reef
Authors: Smith Adam K. , Cook Nathan , Songcuan Al , Brown Rachelle E. , Molinaro Gemma , Saper Julia , Keane Kristin 
Published: March 2024

SummaryCoral reef management techniques such as relocation and transplantation are increasingly implemented in the context of increasing coastal development and a global decline of coral reefs over the last 30 years. A 170 m submarine desalination pipeline was constructed in 2020 to discharge wastewater from the desalination plant for Hayman Island resort, Whitsundays, Queensland, Australia. Pre‐construction site assessments were conducted indicating a healthy, diverse and recovering coral community between intertidal and 12 m depth in the proposed route of the pipeline. Mitigation options included the selection of a pipeline route that minimised impact on coral, and relocation and transplantation of hard corals. Two hundred and four corals comprising 35 species from 15 genera, with estimated sizes ranging from small (less than 2 kg) to extra large (over 50 kg), were relocated from the pipeline footprint to a similar nearby site. The estimated total weight of relocated corals was 873–2850 kg. The most common species transplanted were Hump Coral (Porites lutea) (27%), Lesser Star Coral (Goniastrea aspera) (8.3%) and Starflower Coral (Astreopora ocellata) (7.8%). Individual coral survivorship and growth was monitored at zero, one, six, 12 and 24 months. After 24 months total coral survival was 77.5%. The survivorship of relocated coral exceeded the mean for global coral restoration projects and was deemed successful by the regulator. To assist benchmarking of future coral relocation projects we propose a standard of below 50% as poor, 50–60% as below average, over 60% as acceptable and over 80% coral survival at two years as excellent.
Global patterns and determinants of multiple facets of plant diversity
Authors: Tordoni Enrico , Carmona Carlos Pérez , Toussaint Aurèle , Tamme Riin , Pärtel Meelis 
Published: March 2024

AbstractAimCombining different biodiversity dimensions can reveal new diversity patterns disclosing the relative roles of historical, environmental and anthropogenic factors in shaping global seed plant diversity.LocationGlobal.Time periodPresent.Major taxa studiedVascular plants.MethodsWe collated a database encompassing taxonomic (249,000 species), functional and phylogenetic information (34,694 species) of seed plants across different regions of the world. Species richness in each region was weighted accounting for their phylogenetic and functional distinctiveness, obtaining a new metric—μ‐diversity—which was modelled to disentangle the relative roles of historical factors such as climate variability since the Last Glacial Maximum (LGM), environmental features (e.g. actual evapotranspiration—AET) and anthropogenic factors (past and current).ResultsHigher μ‐diversity was observed in Papuasia, South East Asia, Australia and Central America, whereas the lowest values were primarily located in the Northern Hemisphere. Climate variability and AET were the most important determinants of μ‐diversity and individual diversity facets, whereas the importance of past human impacts (i.e. the onset of pastoralism) equated or exceeded those of the present ones.Main conclusionsOur integrative approach proved more sensitive in describing species diversity patterns. Few areas on Earth host high and unique proportions of multiple diversity facets and individual diversity facets contribute differently to μ‐diversity across continents. Historical climate stability and water‐energy dynamics strongly affect species diversity, but we also observed that past land‐use legacy may have influenced current plant diversity, which is under intense anthropogenic pressure, especially in Asia as well as in Central and South America.
Benefits and risks of non‐factor therapies: Redefining haemophilia treatment goals in the era of new technologies
Authors: Mancuso Maria Elisa , Croteau Stacy E. , Klamroth Robert 
Published: March 2024

AbstractIntroductionOver the last decades progress in haemophilia treatment has been remarkable and prophylaxis with clotting factor concentrates in haemophilia A and B has been established as the standard of care in individuals with haemophilia and a severe bleeding phenotype. Besides clotting factor products with prolonged half‐life non‐factor therapies were developed which enable prophylaxis via subcutaneous administration. Factor VIIIa mimetics like emicizumab facilitate the coagulation pathway and are used in routine clinical practice for indivdiduals with haemophilia A. Rebalancing therapeutic agents like fitusiran, concizumab, marstacimab and serpin PC block the anticoagulant pathway and clinical trials using these products in individuals with haemophilia A and B are ongoing.Aim and MethodsA narrative review to asess the benefits and risks of non‐factor therapies taking in to account re‐defined haemophilia treatment goals.ResultsProphylaxis for prevention of bleeds using non‐factor products by subcutaneous administration is effective and results in reductions of bleeding episodes in individuals with haemophilia A or B with and without inhibitors. The treatment with emicizumab showed tolerable safety both in clinical trials and long‐term real‐world observations with few thrombotic events. In some clinical trials with rebalancing therapies (fitusiran and concizumab) thrombotic events occurred. Monitoring of the haemostatic function of novel therapies especially with concomitant haemostatic treatment is not yet established.ConclusionWith the advent of novel therapeutic agents including factor concentrates with ultra‐long half‐life and improved FVIIIa mimetics aimed at raising the bar of protection into the non‐hemophilic range redefinition of haemophilia treatment goals is eagerly needed.
Administrative burden in older adults: A look at SNAP
Authors: Negoita Marian , Levin Madeleine , Paprocki Anne , Goger Annelies 
Published: March 2024

AbstractAn extensive literature has shown that the rules that govern access to social safety net programs create undue administrative burdens for citizens in accessing the programs. In this paper, we contribute to this literature by describing the experience of older adults with one US social safety net program, the Supplemental Nutrition Assistance Program. Our study gathered data from a total of 267 older adults through interviews and focus groups. Many of our respondents had recently experienced several financial, health, and life crises which affected their ability to seek information, memorize important details, and plan adequately. The main finding of the study is that older adults often experience multiple challenges whose effects tend to amplify each other, affecting their decision‐making abilities. The findings suggest that policies that simplify eligibility processes, reduce the amount of paperwork, and minimize the number of client‐caseworker encounters, have the potential to facilitate greater program access.
Work–family and family–work conflict and negative attitudes toward having children: A multilevel cross‐national analysis
Authors: Jiang Chaoxin , Ren Cheng , Jiang Shan 
Published: March 2024

AbstractThe relationship between work–family and family–work conflict and attitudes toward having children has been established; however, how it varies by different national cultural dimensions remains unclear. This study seeks to address this gap by examining the moderating effects of two cultural dimensions, individualism–collectivism and indulgence‐restraint, across a sample of 40 countries and regions. Data from the 2012 round of the International Social Survey Program (ISSP) are utilized, encompassing 30,613 participants (M = 43.33 years old; SD = 13.22). Multilevel modeling is employed to integrate individual‐level and country‐level factors and examine the cross‐level moderating effects. The findings demonstrate that both work–family conflict and family–work conflict are positively associated with negative attitudes toward having children. Moreover, these relationships between work–family and family–work conflicts and negative attitudes toward having children are more pronounced in individualistic societies compared with collectivist societies. Furthermore, these relationships are stronger in restrained societies as opposed to indulgent societies. These results underscore the significance of addressing work–family and family–work conflict both at the policy and practice levels and emphasize the need for considering cultural dimensions.
Large families and poverty in Austria: What explains their disproportionate risk of experiencing income poverty?
Authors: Heitzmann Karin , Pennerstorfer Astrid 
Published: March 2024

AbstractIn many countries, large families with three or more children have high income poverty rates. In this article, we aim to understand why this is the case by examining the relevance of family structure, socio‐economic characteristics, and welfare state transfers targeted at this family form. For our analyses, we use cross‐sectional data from three waves (2017–2019) of the Austrian European Union Statistics on Income and Living Conditions dataset. Our results, based on descriptive statistics, logistic regressions, and decomposition analyses, confirm the higher poverty risk of large families compared with smaller families. However, when differentiating between poor and non‐poor families, it is not the family type that seems to be relevant in explaining the poverty risk, but rather the parental work intensity, the age of the youngest child, the place of residence, being a single‐parent household, and the parental migration background. Moreover, cash transfers from the welfare state, in particular family benefits, contribute to reducing poverty for a significant number of large families. Policy makers are therefore well advised to either further increase the cash transfers targeted at large families, and/or to improve the employability and ultimately the work intensity of parents in large families in order to reduce their income poverty risk.
Influence of limited mouth opening in children on intraoral scanning accuracy: An in vitro study
Authors: Ye Ju Ri , Park Seung Hwan , Lee Hyeonjong , Hong Seoung‐Jin , Chae Yong Kwon , Lee Ko Eun , Lee Hyo‐Seol , Choi Sung Chul , Nam Ok Hyung 
Published: March 2024

AbstractBackgroundAlthough intraoral scanning is highly reliable, little is known about its accuracy in young children with limited mouth‐opening ability.AimTo determine the accuracy of intraoral scans based on the degree of mouth opening.DesignTo simulate mouth opening in children with primary dentition, three groups (n = 5 per group) were allocated by maximum mouth opening of 30, 37 and 40 mm. After the primary dentition model was connected to a dental phantom, intraoral scanning was performed using iTero and TRIOS4. The scanned files were digitally evaluated. Root mean square values were calculated to assess trueness and precision.ResultsiTero showed deviations of three‐dimensional trueness of 0.067 ± 0.008, 0.063 ± 0.001 and 0.065 ± 0.005 mm, and TRIOS4 of 0.07 ± 0.002, 0.064 ± 0.003 and 0.066 ± 0.002 mm in the 30, 37 and 40 mm groups, respectively. There were no significant differences in either mouth opening (p > .017) or the intraoral scanners (p > .05). The same statistical results were obtained for precision, with the exception of the 30 mm of mouth opening.ConclusionsWithin the limits of this study, limited mouth opening hardly influenced the accuracy of intraoral scanning.
Phase transition mechanism and long‐term stability of LiF‐assisted sintered Li2MgxZrO3+x microwave dielectric ceramics
Authors: Chu Xin , Gan Lin , Jiang Juan , Wang Jinzhao , Zhang Tianjin 
Published: March 2024

AbstractHerein, Li2MgxZrO3+x (x = 0–1) +2 wt.% LiF ceramics with a rock salt structure were prepared by the solid‐state reaction method. The phase transition mechanism was systematically investigated by X‐ray diffraction, and first‐principles calculations. With a gradual increase in MgO content, the samples underwent a monoclinic‐Li2ZrO3 to tetragonal‐Li2ZrO3 to tetragonal‐Li2MgZrO4 to cubic‐phase transition. The variations of the microwave dielectric properties due to the phase transition were systematically analyzed by the multi‐phase mixtures law. In addition, CO2 adsorption of the samples was quantitatively analyzed by X‐ray photoelectron spectroscopy, and the long‐term stability of the Q × f of the samples was investigated. The optimal microwave dielectric properties were obtained in Li2Mg0.2ZrO3.2 ceramic at 950°C: εr = 19.5, Q × f = 44 500 GHz, and τf = 2.6 ppm/°C. In addition, the ceramic samples were compatible with Ag, which indicates that Li2MgxZrO3+x (x = 0−1) +2 wt.% LiF is a promising material for low‐temperature co‐fired ceramics.
Large room temperature magnetoelectric response in quasi 1–2 nanocomposite films on mica substrate
Authors: Pan Weijuan , Liu Yuanji , Ao Yuan , Zhou Peng , Fedulov Fedor , Fetisov Yuri , Zhang Tianjin , Xing Sainan , Srinivasan Gopalan , Qi Yajun 
Published: March 2024

AbstractA novel quasi 1–2 type magnetoelectric (ME) nanocomposite films composted of one‐dimensional CoFe2O4 nanofibers and two‐dimensional PbZr0.2Ti0.8O3 films on flexible mica substrate have been designed and fabricated. The ME coupling effects have been greatly enhanced due to the release of the clamping effect and the high strain transfer efficiency between the large aspect ratio of the nanofibers and ferroelectric thin films. The release of the clamping effect was confirmed by reducing the thickness of the mica substrate, in which the piezoelectric coefficient and ME coupling coefficient of the nanocomposite films have been greatly boosted by the decrease in the mica thickness. A large direct ME coupling coefficient of 630 mV/(cm Oe) and a converse ME coupling coefficient of 1.43 × 10−8 s/m have been achieved in the quasi 1–2 nanocomposite film with a substrate thickness of 25 µm. Furthermore, the stain‐mediated ME coupling was revealed by magnetic field/electric field‐induced local ferroelectric/magnetic domain switching dynamics.
The association of leader–member exchange and team–member exchange with nurses' innovative behaviours: A cross‐sectional study
Authors: Cheng Liangying , Wei Wanhong , Zhang Jinyan , Yao Ying , Zhang Yanhui , Zhu Weiyan 
Published: March 2024

AbstractAimTo measure the association of leader–member exchange and team–member exchange with nurses' innovative behaviours through social exchange theory.BackgroundThe field of nursing is actively advocating innovation. Other fields have proven that leader–member exchange and team–member exchange can promote innovative behaviour, but such an association is not clear in nursing.DesignA cross‐sectional study.MethodsA total of 560 nurses were selected from five tertiary hospitals in Henan Province (China) by multistage sampling. Data were collected from a self‐report questionnaire. Thirty nurses in the pre‐survey were used to verify the validity of the questionnaire. SPSS PROCESS macro was used to verify the association of leader–member exchange and team–member exchange with nurses' innovative behaviours.ResultsLeader–member exchange and team–member exchange were significantly associated with nurses' innovative behaviours, and team–member exchange had a mediating effect on the relationship between leader–member exchange and innovative behaviour.ConclusionsLeader–member exchange and team–member exchange positively affect nurses' innovative behaviours. Leader–member exchange can promote nurses' innovative behaviours through the mediating role of team–member exchange.ImpactThis study indicated that leader–member exchange and team–member exchange should be given more attention in promoting nurses' innovative behaviours. This finding has implications for the promotion of innovative behaviours in nurses. Leaders need to focus on the innovative needs of nurses and offer support. Meanwhile, leadership training programs are necessary for managers to create positive team relationships.Patient or Public ContributionNo patient or public involvement.