bluuebunny/crossref_metadata_2025_split huggingface dataset:
Study on the effect of intracoronary Adenosine on the incidence of myonecrosis after elective percutaneous coronary intervention
Authors: Ahsan Md Razib , Siddique Md Abu , Haque KMHS Sirajul , Ahsan Syed Ali , Ahmed Md Khurshed , Rahman Md Mukhlesur 
Published: February 2009

Appearance of serum creatine kinase MB fraction (CK-MB), reflecting the periprocedural myonecrosis, after successful percutaneous coronary intervention (PCI) is associated with future cardiac adverse events. The intracoronary adenosine on the incidence of myonecrosis after elective PCI was assessed. In this prospective, case control study with a total of 60 patients, 30 cases pretreated with 50 micro grams bolus intracoronary adenosine before advancement of guidewire and 30 controls not pretreated was studied during elective PCI. Both groups received statin and loading dose of Clopidogrel. Myonecrosis was assessed by CK-MB level after PCI. Post procedural myonecrosis occurred in 16.7 % (n=5) in case group and 36.7 % (n=11) in control group (OR=1.818; 95% CI 0.841; P=0.080). The result is not statistically significant but shows that the incidence of myonecrosis was reduced from 36.7% to 16.7%. Intracoronary adenosine reduces the incidence of myonecrosis after elective PCI. Keywords: Adenosine; Creatine kinase MB fraction; Intracoronary; Myonecrosis; Percutaneous coronary intervention; Periprocedural. Â doi:10.3329/uhj.v4i2.2068 University Heart Journal Vol. 4 No. 2 July 2008 p19-23
Study of angiographic association of atherosclerotic renal artery stenosis with coronary artery disease in Bangladesh
Authors: Islam Md Sirajul , Mahmood Manzoor , Haque KMHS Sirajul , Abu Siddique Md , Banerjee Sajal Krishna , Islam M Nazrul , Ahsan Sayed Ali , Rahman Fazlur , Ahmed Chaudhury Meshkat , Safiuddin Md , Hasan ATM Iqbal , Ahmed Md Khurshed , Subedi Bikas 
Published: February 2009

This retrospective observational study aimed to see the angiographic association of atherosclerotic renal-artery stenosis (ARAS) with coronary artery disease in Bangladesh. It was conducted in department of cardiology, University Cardiac Centre, Bangabandhu Sheikh Mujib Medical University, Dhaka from January 2007 to January 2008. A total of 250 patients with coronary artery involvement, on non-emergent coronary angiogram who underwent either selective or nonselective renal angiography were enrolled in this study. Among 250 patients, 52 (20.8%) patient had single vessel disease (SVD), 49 (19.6%) and 149 (59.6%) had double vessel disease (DVD) and triple vessel disease (TVD) respectively. ARAS was detected in 37.2% or 93 patients. ARAS tends to increase with age. In age group of 30-40, ARAS is 7.4% whereas in age group of 51-60 years it is 41%. The incidence of ARAS is high in 50.25Â±9.98years; p=0.0001. 33.3% male patients with CAD had ARAS whereas it was 44.3% in female patients with CAD. ARAS is more common in female 44.3% vs 33.3%; p=0.02. ARAS prevalence increased with the number of stenosed coronary arteries (3.8% in 1-vessel, 26.5% in 2-vessel, 52.3%in 3-vessel CAD; p=.0001.). Hypertension and angiographically proven CAD were independent predictors of ARAS (p=0.0001). In conclusion, ARAS prevalence and severity increases with the number of arterial territories involved and CAD severity. Hypertension and 2-3-vessel-CAD were identified independent predictors of ARAS. Â doi:10.3329/uhj.v4i2.2069 University Heart Journal Vol. 4 No. 2 July 2008 p24-27
Stem cell therapy- An update
Authors: Rahman Fazlur , Subedi Bikash , Awal Anisul , Haque KMHS Sirajul , Siddique Md Abu , Banerjee Sajal Krishna , Safiuddin Md , Ahmed Chaudhury Meshkat , Ahsan Syed Ali , Anam Khairul , Ahmed Md Khurshed , Rahman Md Mukleshur , Sultan Md Ashraf Uddin , Rashid Md A , Salman Mohammad 
Published: February 2009

Stem cells are one of the most fascinating areas of biology today. Stem cells have two important characteristics that distinguish them from other types of cells. First, they are unspecialized cells that renew themselves for long periods through cell division. The second is that under certain physiologic or experimental conditions, they can be induced to become cells with special functions. Stem cells can be obtained from several sources including spare embryos, special purposes embryos, aborted fetus, umbilical cords, adult tissue or organs, cadavers. The procedure of adult stem cell therapy involves several steps including extraction of cells from various sources, separation by surface markers using FACS, growth in specific culture media and injection into target organs. This modern aspect of regenerative or reparative medicine can be applied for cardiac diseases (coronary artery diseases, heart failure, non ischaemic cardiomyopathies), skin replacement, Diabetes, spinal cord injury, neurodegenerative disease like Parkinsonism, stroke. In future, it may become possible the use of stem cells in organ transplantation. Â Â doi:10.3329/uhj.v4i2.2076 University Heart Journal Vol. 4 No. 2 July 2008 p.46-48
periodR – an R Package to Calculate Long-term Cancer Survival Estimates Using Period Analysis
Authors: Gondos A. , Brenner H. , Holleczek B. 
Published: February 2009

Summary
Objective: In this paper, a software package for the R language and system for statistical computing is presented for computation of long-term cancer survival estimates based on the period analysis approach. The period analysis approach provides up-to-date long-term survival estimates of concurrently diagnosed patients, enables early detection of recent changes in long-term prognosis of cancer patients and provides better survival predictions for recently and currently diagnosed patients than traditional cohort-based approaches.
Methods: Computation of absolute and relative survival estimates (both conditional follow-up year-specific and cumulative survival estimates) and their standard errors is based on standard actuarial methodology. For relative survival estimation the “Ederer II” and “Hakulinen” method were implemented.
Results: The package may be used for period analysis as well as traditional cohort-based survival estimation. The package further provides functions for the export of survival estimates for use with spreadsheet programs and for plotting survival curves. The application of period analysis is illustrated using stomach cancer data included in the package.
Conclusion: Application of period analysis has gradually increased in recent years but continues to be limited by availability of affordable and easy-to-use software tools. The presented R package aims at closing this gap and will further facilitate the use of period analysis for the research community working with population-based cancer registry data. The software is freely available for download on the website of the Saarland Cancer Registry at http://www.krebsregister.saarland.de improve/periodR_en.html.
The Impact of SOA for Achieving Healthcare Interoperability
Authors: Mantas J. , Daskalakis S. 
Published: February 2009

Summary
Objectives: The evaluation of a service-oriented prototype implementation for healthcare interoperability.
Methods: A prototype framework was developed, aiming to exploit the use of service-oriented architecture (SOA) concepts for achieving healthcare interoperability and to move towards a virtual patient record (VPR) paradigm. The prototype implementation was evaluated for its hypothetical adoption. The evaluation strategy was based on the initial proposition of the DeLone and McLean model of information systems (IS) success [1], as modeled by Iivari [2]. A set of SOA and VPR characteristics were empirically encapsulated within the dimensions of IS success model, combined with measures from previous research works. The data gathered was analyzed using partial least squares (PLS).
Results: The results highlighted that system quality is a partial predictor of system use but not of user satisfaction. On the contrary, information quality proved to be a significant predictor of user satisfaction and partially a strong significant predictor of system use. Moreover, system use did not prove to be a significant predictor of individual impact whereas the bi-directional relation between use and user satisfaction did not confirm. Additionally, user satisfaction was found to be a strong significant predictor of individual impact. Finally, individual impact proved to be a strong significant predictor of organizational impact.
Conclusions: The empirical study attempted to obtain hypothetical, but still useful beliefs and perceptions regarding the SOA prototype implementation. The deduced observations can form the basis for further investigation regarding the adaptability of SOA implementations with VPR characteristics in the health-care domain.
Development of a National Core Dataset for Preoperative Assessment
Authors: Ahmadian L. , Cornet R. , Kalkman C. , de Keizer N. F. 
Published: February 2009

Summary
Objective: To define a core dataset for preoperative assessment to leverage uniform data collection in this domain. This uniformity is a prerequisite for data exchange between care providers and semantic interoperability between health record systems.
Methods: To design this core dataset a combination of literature review and expert consensus meetings were used. In the first meeting a working definition for “core dataset” was specified. Subgroups were formed to address major headings of the core dataset. In the following eight meetings data items for each subheading were discussed. The items in the resulting draft of the dataset were compared to those retrieved from an earlier literature review study. In the last two expert meetings modifications of the dataset were performed based on the result of this literature study.
Results: Based on expert consensus a draft dataset including 82 data items was designed. Seventy-six percent of data items in the draft dataset were covered by the literature study. Nine data items were modified in the draft and 14 data items were added to the dataset based on input from the literature review. The final dataset of 93 data items covers patient history, physical examination, supplementary examination and consultation, and final judgment.
Conclusions: This preoperative-assessment dataset was defined based on expert consensus and literature review. Both methods proved to be valuable and complementary. This dataset opens the door for creating standardized approaches in data collection in the preoperative assessment field which will facilitate interoperability between different electronic health records and different users.
Care of the collection in University of Peradeniya library: strategic planning for the preventive conservation
Authors: Alahakoon Champa NK 
Published: February 2009

This paper discusses some problems which prevail with regard to preventive conservation of rare materials presently available in the university library. It reveals the problems that have arisen due to deteriorating factors and negligent areas of the library, such as lack of awareness of the importance of the documents and materials; lack of positive thinking on preventive conservation; shortage of trained staff, equipment and chemicals; and lack of funds. It points out the importance and need of preservation of different kinds of material including wooden objects and paintings and the factors that need to be addressed with regard to preventive conservation. Lastly it highlights strategic planning for preventive conservation which needs to be implemented.Key words: Collection care, preservation of rare materials, strategic planning for preservation doi: 10.4038/jula.v12i0.326 Journal of the University Librarians Association of Sri Lanka (Vol. 12) 2008 p.1-16
Information needs and information use: a research based on Social Scientists at the Open University of Sri Lanka
Authors: Gunasekera Damayanthi 
Published: February 2009

This study focuses on the information needs, use of resources by required by academics of the Social Sciences Department at the Open University of Sri Lanka (OUSL). The questionnaire and interview were used as instruments in this study to collect data. The response rate was 100% due to higher cooperation. A conceptual model was used to identify and assess the information needs of the academic staff. The study revealed that the multiple role of OUSL academic in the distance mode is different to that of an academic in the conventional setup hence their information needs are different, Academic in the distance mode depends heavily on the Internet, text books and subject journals as their major sources of information to fulfill their different needs. OUSL main library is used for writing and to revising course materials. Research needs are mainly fulfilled through special libraries in the country. Main obstacle that they face is getting sufficient materials in their specialized subject areas. Therefore, both printed and electronic collection of the OUSL library must be strengthened to meet the specific research needs of the academic staff members. Key words: Information needs, Social scientists, Library usage, Teaching higher education, Distance education system, Academic staff needs doi: 10.4038/jula.v12i0.328 Journal of the University Librarians Association of Sri Lanka (Vol. 12) 2008 p.47-67
Knowledge Management in Banking Industries: uses and opportunities
Authors: Jayasundara Chaminda Chiran 
Published: February 2009

This paper reviews the prevailing literature on Knowledge Management in banking industries. The purpose of KM is to value to information resides in organizations resulting value addition to their tasks and ultimately to approach competitive advantage. Most common KM applications identified in the banking industries are risk management. Customer Relationship Management/Marketing (CRM), performance evaluation etc, Decision Support Systems (DSS), data where houses and data mining are rapidly growing techniques in this particular sector. However, most banks around the world do not use comprehensive knowledge management systems while other financial organizations in the same disciplines do. Keywords: Knowledge Management, Ban king Industries, Information Management doi: 10.4038/jula.v12i0.329 Journal of the University Librarians Association of Sri Lanka (Vol. 12) 2008 p.68-84
What's behind crashing memories? Plausibility, belief and memory in reports of having seen non‐existent images
Authors: Smeets Tom , Telgen Sebastian , Ost James , Jelicic Marko , Merckelbach Harald 
Published: February 2009

AbstractThe present study investigated the precise nature of crashing memory reports: Are they truly memories or are they based on beliefs? We asked 88 individuals whether they had seen non‐existent footage of the Pim Fortuyn assassination and conducted thorough post‐experimental interviews. Two‐thirds of our participants falsely reported having seen the footage, while less than 10% also reported details that they could not have seen. Moreover, plausibility ratings of having seen the images were higher than false belief ratings, which in turn were higher than false memory ratings. After having been fully debriefed, 81% of the participants who reported crashing memories attributed their false report to their lack of a full understanding of the critical question. Another 10% of this subsample stated that they truly remembered the images (i.e. false memories). Thus, only a small subset of crashing memory reports seems to be induced by false beliefs and/or false memories. Copyright © 2009 John Wiley & Sons, Ltd.
Fabrication of Ordered Nanostructured Arrays Using Poly(dimethylsiloxane) Replica Molds Based on Three‐Dimensional Colloidal Crystals
Authors: Choi Hong Kyoon , Kim Mun Ho , Im Sang Hyuk , Park O Ok 
Published: February 2009

AbstractHexagonally arrayed structures of colloidal crystals with uniform surface are a good candidate for master molds to be used in soft lithography. Here, the fabrication of periodically arrayed nanostructures using poly(dimethylsiloxane) (PDMS) molds based on three‐dimensionally (3D) ordered colloidal crystals is reported. A robust, high‐quality 3D colloidal‐crystal master molds is prepared using the colloidal suspension containing a water‐soluble polymer. The surface patterns of the 3D colloidal crystals can then be transferred onto a polymer film via soft lithography, by means of the replication of the surface pattern with PDMS. Various hexagonally arrayed nanostructure patterns can be fabricated, including close‐packed and non‐close‐packed 2D arrays and honeycomb structures by the structural modification of the 3D colloidal‐crystal templates. The replicated hexagonally arrayed structures can also be used as templates for producing colloidal crystals with 2D superlattices.
Nanopatterning Soluble Multifunctional Materials by Unconventional Wet Lithography
Authors: Cavallini Massimiliano , Albonetti Cristiano , Biscarini Fabio 
Published: February 2009

AbstractMolecular multifunctional materials have potential applications in many fields of technology, such as electronics, optics and optoelectronics, information storage, sensing, and energy conversion and storage. These materials are designed exhibit enhanced properties, and at the same time are endowed with functional groups that control their interactions, and hence self‐organization, into a variety of supramolecular architectures. Since most of the multifunctional materials are soluble, lithographic methods suitable for solutions are attracting increasing interest for the manufacturing of the new materials and their applications. The aim of this paper is to highlight some of the recent advances of solution‐based fabrication of multifunctional materials. We explain and examine the principles, processes, materials, and limitations of this class of patterning techniques, which we term unconventional wet lithographies (UWLs). We describe their ability to yield patterns and structures whose feature sizes range from nanometers to micrometers. In the following sections, we focus our attention on micromolding in capillaries, lithographically controlled wetting, and grid‐assisted deposition, the most used methods demonstrated to lead to fully operating devices.
Metal Chalcogenide Clusters on the Border between Molecules and Materials
Authors: Corrigan John F. , Fuhr Olaf , Fenske Dieter 
Published: February 2009

AbstractThe preparative and materials chemistry of high nuclearity transition metal chalcogenide nanoclusters has been in the focus of our research for many years. These polynuclear metal compounds possess rich photophysical properties and can be understood as intermediates between mononuclear complexes and binary bulk phases. Based on our previous results we discuss herein recent advances in three different areas of cluster research. In the field of copper selenide clusters we present the synthesis of monodisperse, nanostructured α‐Cu2Se via the thermolysis of well‐defined cluster compounds as well as our approaches in the synthesis of functionalized clusters. In case of silver chalcogenides we established a strategy to synthesis cluster compounds containing several hundreds of silver atoms with the nanoclusters arranging in a closely packed crystal lattice. Finally the presented chalcogenide clusters of the group 12 metals (Zn, Cd, Hg) can be taken as model compounds for corresponding nanoparticles as even the smallest of frameworks display a clear structural relationship to the bulk materials.
Modeling of CO2 gasification of carbon for integration with solid oxide fuel cells
Authors: Lee Andrew C. , Mitchell Reginald E. , Gür Turgut M. 
Published: February 2009

AbstractThis modeling study focuses on gasification of carbon by CO2 in a minimally fluidized bed containing a solid oxide fuel cell (SOFC). Kinetic parameters for a five‐step reaction mechanism characterizing the Boudouard reaction (C + CO2 → 2CO) were determined thermogravimetrically at 1 atm from 973 to 1273 K. Experimentally determined kinetic parameters are employed in a transport model that predicts velocities and gas concentration profiles established in the carbon bed as a consequence of convection, diffusion, and heterogeneous reaction. The model is used to simulate the effect of an imbedded SOFC, in contact with the carbon bed. Although the model does not assume particular I‐V characteristics for the fuel cell, it indicates that current densities in the practical range of 100–1000 mA/cm2 can be supported. Results show that temperature strongly affects the current density, whereas CO2 flow rate has only a weak effect. © 2009 American Institute of Chemical Engineers AIChE J, 2009
A novel polymorphic purine complex at the 1.5 kb upstream region of the human caveolin‐1 gene and risk of Alzheimer's disease; Extra‐short alleles and accumulated allele homozygosity
Authors: Heshmati Y. , Mirabzadeh A. , Feizzade G. , Gilanipour M. , Etminan M.R. , Khoram Khorshid H.R. , Kamali K. , Fakhri M. , Moghimi N. , Najmabadi H. , Ohadi M. 
Published: February 2009

AbstractCrucial interaction of caveolin‐1 (CAV1) with β‐ and γ‐secretases, and aberrant expression of the gene encoding this protein in Alzheimer's disease (AD) support a role for CAV1 in the pathophysiology of this disease. We report a novel polymorphic purine complex stretching ∼150 bp of genomic DNA at the 1.5 kb upstream region of the human CAV1 gene, alleles and genotypes of which are associated with sporadic late‐onset AD. Extra‐short alleles were observed in the case group that were absent in the control subjects. Remarkably, 63% of these alleles were observed to be homozygous in length, forming 23.7% of the homozygote length compartment in the AD cases (χ2 = 19.08, df = 1, P < 0.000007). Increased homozygosity for length was also observed at this region in the Alzheimer's cases, for the allele lengths shared by the case and control groups [(χ2 = 30.75, df = 1, P < 0.0000000, OR = 4.54, CI 95% (2.56–8.3)]. This region contains GGAA and GAAA motifs, the consensus binding sites for the Ets and IRF family transcription factors, respectively, and is highly conserved in distantly related non‐human primates in respect with location and motif sequence. The effect of this complex sequence on the expression of CAV1, and the related mechanisms in the pathophysiology of AD remain to be clarified. © 2008 Wiley‐Liss, Inc.
How Neandertals inform human variation
Authors: Wolpoff Milford H. 
Published: February 2009

AbstractSince their first discovery, Neandertals have served as an out‐group for interpreting human variation. Their out‐group role has changed over the years because in spite of the fact that Neandertals are the most abundant of all fossil remains (or perhaps because of this) their interpretation is the most controversial of all human fossils. Many believe them to be a different, albeit human‐like species, but recent genetic evidence supports anatomical interpretations indicating that interbreeding with other humans was an important aspect of human evolution. The combination of anatomical difference and restricted gene flow between populations suggests the possibility that Neandertals may have been a true human race. Am J Phys Anthropol 2009. © 2009 Wiley‐Liss, Inc.
Beyond Reppe: Building Substituted Arenes by [2+2+2] Cycloadditions of Alkynes
Authors: Galan Brandon R. , Rovis Tomislav 
Published: February 2009

AbstractSynthetic sequel: The transition‐metal‐catalyzed [2+2+2] cycloaddition is an established method for the construction of carbocyclic frameworks but is often plagued by poor selectivity. Recent literature paints a promising picture—a more general metal‐catalyzed [2+2+2] cycloaddition can be accomplished intermolecularly using three separate alkynes to furnish highly substituted arenas (see scheme).magnified image