bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Arterial Blood Pressure of the Newborn Infant
Authors: NYBERG RUNE , WESTIN BJÖRN 
Published: January 2008

SummaryThe blood pressure in the umbilical artery was recorded in 20 mature normal newborn infants immediately after birth by an electromanometer. The thoracic movements caused considerable variations in the pressure recorded. The mean pressure was 87.8 ± 3.0/54.5 + 2.7 mm Hg.La pression arterielle du nouveau‐né.I. La pression de l'artère ombilicale du nouveau‐né normal à terme.On mesura, à l'électromanomètre, la pression de l'artère ombilicale de 20 nouveaux‐nés normaux nés à terme tout de suite après la naissance. Les mouvements thoraciques eausèrent des variations importantes de la pression enregistrée. La pression moyenne fut de 87,8 +3,0/54,5 ±2,7 mm de mercure.Der arterielle Blutdruch beim neugeborenen Kind.I. Der Blutdruch in der Nabelarterie des normalen, vollreifen Neugeborenen.Der Blutdruck in der Nabelarterie wurde bei 20 vollreifen normalen neugeborenen Kindern unmittelbar nach der Geburt mit Hilfe eines Elektromanometers bestimmt. Die Bewegungen des Brustkorbs vervirsachten wesentliche Schwankungeri in dem aufgezeichneten Druck. Der durchschnittliche Blutdruck betrug 87,8±3,0/54,5±2,7 mm Hg.De la presión sanguined arterial en el recién nacido.I. La presión sanguínea en la arteria umbilical del neonato normal nacido a término.La presión sanguínea en la arteria umbilical de 20 neonates normales nacidos a término, ha sido registrada inmediatamente después de nacer, mediante un electromanómetro. Los movimientos torácicos determinaron variaoiones considerables en las presiones registradas. Presión media: 87,8 ±3,0/54,5 ± 2,7 mm mercuric
Ellis‐Van Creveld Syndrome Report of Two Cases in Siblings
Authors: MITCHELL F. N. , WADDELL W. W. 
Published: January 2008

Summary1. Two cases of the Ellis‐Van Creveld syndrome are presented. These are the first cases reported in siblings.2. It is suggested that strabismus, pseudo‐hairlip, and changes in metacarpal ossification centers are additional, though less frequent components of the syndrome.3. Ecto‐mesodermal dysplasia is proposed as a more descriptive name for this syndrome.Le syndrome dapos;Ellis‐Van Creveld. Rapport sur deux cas chez des enfants de memes parents.Présentation de deux cas de syndrome dapos;Ellis‐Van Creveld. Ce sont les deux premiers cas rapportés sur des enfants de memes parents. II a été supposeé que le strabisme, le pseudo bec‐de‐lièvre et les changements dans les centres de lapos;ossification métacarpienne sont des composants supplémentaires du syndrome, bien qu'ils soient moins fréquents. On a proposé d'appeler ce syndrome: dysplasie de l'ecto‐mésoderme, étant un mon plus descriptif.Das Ellis‐ Van Creveldsche Syndrom. Bericht über zwei Fälle bei Geschwistem.Zwei Fälle von Ellis‐Van Creveldschem Syndrom werden besehrieben. Diese sind die ersten bei Geschwistern, iiber die berichtet wird. Die Ansicht wird ausgesprochen, dass Strabismus, Pseudohasenscharte und Veränderungen in metakarpalen Ossifikationszentren zusätzliche, wenn auch weniger häufige Bestandteile des Syndroms sind. Ekto‐mesodermale Dysplasie wird als ein, dieses Syndrom besser beschreibender Name, vorgesehlagen.Casuística del síndrome de Ellis‐Van Creveld en dos descendientes directos.Se exponen dos casos de síndrome de Ellis‐Van Creveld. Son éstos los primeros registrados en descendientes directos. Se sugiere que el estrabismo, el seudo labio leporino y los cambios en los centros de osificación metacarpiana, son constitutivos adicionales de este sindrome, aunque menos frecuentes. Se propone para este síndrome el nombre más descriptivo de displasia ectomesoderma.
Non‐spherocytic Haemolytic Anaemia in Mother and New‐born Infant
Authors: SODERHJELM LARS 
Published: January 2008

SummaryA case is described of non‐spherocytic haemolytic anaemia in a woman. The condition was aggravated during her two pregnancies, and exhibited some megaloblastic features. The first child was healthy, but the second developed anaemia with reticulocyte response first to folic acid, then to a liver preparation, and finally to cortisone and blood transfusion. Haemolytic anaemia was undoubtedly present, but the child also had folic‐acid and vitamin B12 deficiency.
Motions of the Pharynx Associated with Initial Aeration of the Lungs of the Newborn Infant1
Authors: BOSMA JAMES F. , LIND JOHN , GENTZ N. 
Published: January 2008

SummaryIn five of eight subjects satisfactorily observed by successive radiographs within the immediate newborn period, the initial air inflation of the lung was found to be associated with a sequential distention and compression of the pharynx cavity. It is acknowledged that these observations are preliminary and incomplete. But a similarity is recognized to the glossopharyngeal breathing reported in respiratory‐deficient poliomyelitic subjects and also a part of patterns of manifestation of focal seizures in the pharynx area of an infant.
Nocturnal Enuresis in Twins II.
Authors: HALLGREN BERTIL , LARSSON HARRY , RUDHE ULF 
Published: January 2008

Summary1. A study by means of micturition urethro‐cystography of changes in the lower urinary tract and of the effective bladder capacity in children with nocturnal enuresis was performed on the basis of a randomly selected twin series. The material comprised 40 same‐sexed twin pairs in which a t least one of the partners suffered from persistent nocturnal enuresis, i.e. 49 affected twins and 31 unaffected partners who were used as controls.2. Only minor deviations in the lower urinary tract were found. The investigation failed to show any significant relationship between such deviations and noc turnal enuresis.3. There seems to be no relationship between nocturnal enuresis and the width of the posterior urethra during micturition.4. The statistical analysis indicates that there is no difference in the effective bladder capacity between children with persistent nocturnal enuresis and other children.5. There seems to be no significant relationship between nocturnal enuresis and the occurrence of spina bifida occulta in the lower lumbar and sacral regions.
Venous Hypertension in the Newborn Infant associated with Delayed Clamping of the Umbilical Cord1
Authors: TAYLOR PAUL M. , EGAN THOMAS J. , BIRCHARD EDNA L. , BRIGHT NANCY H. , WOLFSON JEROME H. 
Published: January 2008

SummaryThe mean umbilical vein pressure of 31 normal infants 5 to 89 hours of age was 92.2 mm of normal saline ±12.8 mm (S.D.). Venous pressure was not influenced by age or birth weight.Continuous recordings of umbilical rein pressure were made on 11 infants whose umbilical cords were clamped a t the time of delivery, and on 20 infants whose cords were clamped several minutes after delivery. The highest pressure recorded in the early‐clamped group was 120 mm; 2 of the 11 infants had this pressure. Seventeen of the 20 late‐clamped infants had levels of venous pressure repeatedly in excess of 120 mm during the first 30‐60 minutes of life with return to the normal range at varying rates.Possible effects of a placental transfusion sufficiently large to raise venous pressure on the status of the newborn infant have been discussed briefly.
Renal Tubular Defects in Fibrous Dysplasia of the Bones: Report of Two Cases
Authors: HALVORSEN SVERRE , AAS KJELL 
Published: January 2008

SummaryThe occurrence of renal tubular defects in two cases of fibrous dysplasia of the bones is reported. Case 1 has vitamin D resistant rickets and Case 2 has renal glucosuria and aminoaciduria. The renal defect in Case 2 resembles the syndrome of Luder & Sheldon. According to the present theories on renal function, the site of the renal defects can be located to the proximal tubules in both cases. It is postulated that the renal defects in fibrous dysplasia of the bones are associated congenital lesions.
Neurological Signs in a Juvenile Form of Gaucher's Disease
Authors: HERRLIN KARL‐MAGNUS , HILLBORG PER OLOF 
Published: January 2008

SummaryThe occurrence of progressive cerebral symptoms is described in a juvenile form of Gaucher's disease, in a clinical series assessed uniformly. This series is composed of six persons, still living, between the ages of 6 and 20, belonging to four related families, who all come from a limited area in northern Sweden. All 6 patients have shown the same clinical, his to pathological and his to chemical findings, and all have undergone splenectomy. Two spleens were chemically analysed. Their lipid content was typical of Gaucher's disease. All cases developed skeletal changes within 31/2 years of splenectomy.The cerebral signs consisted of mental retardation in 5 cases, psychotic behaviour disorders in 2 cases, generalised rigidity and jerky movement in 5, epilepsy in 3 and a pathological EEG in them all. Similar signs were not found among the children's relatives.The progressive mental and neurological symptoms indicate a diffuse, progressive encephalopathy, which affects the cortical and sub cortical grey matter. The authors think it likely that the cerebral signs have a vascular origin and are caused by deposition of cerebrosides in the adventitital cells of the cerebral blood vessels. Similar cerebral changes have been described in the infantile form of Gaucher's disease. Splenectomy performed at an early age may have been a provocative factor in the development of these hypothetical vascular changes and of the early skeletal changes.
Studies on Leucin‐Induced Hypoglycemia
Authors: GENTZ JOHAN , LEHMANN ORLA , ZETTERSTRÖM ROLF 
Published: January 2008

SummaryTwo typical nonrelated cases of leucin‐precipitated hypoglycemia are described. Both patients showed evidence of severe atrophy of the brain. Since leucin was found to induce fits even if a fall in the blood sugar was prevented by the continuous administration of glucose, the symptoms in the syndrome of leucin‐induced hypoglycemia may not solely develop as the result of an abnormally low blood sugar level.
Familial Neonatal Hypoglycemia A Syndrome Resembling Foetopathia Diabetica
Authors: HANSSON GÖRAN , REDIN BjÖRN 
Published: January 2008

SUMMARYA clinical and pathologico‐anatomic syndrome resembling that occurring in offspring of diabetic and prediabetic mothers has been described in two overweight newborn sisters. Both patients had convulsions and died during the neonatal period. In one of them where blood glucose determinations were performed a marked hypoglycemia was diagnosed.Since the mother has given birth to quite normal infants between and after the diseased children and because of the fact that there is no evidence of a prediabetic state it is suggested that the syndrome has developed as a consequence of some other metabolic error. The fact that the parents are first cousins supports the supposition that the disease may be genetically determined.
Hyperbilirubinaemia in Full‐Term Newborn Infants A Follow‐Up Study
Authors: KILLANDER A. , MICHAÉLSSON M. , MÜLLER‐EBERHARD U. , SJÖLIN S. 
Published: January 2008

SUMMARYA follow‐up study is presented of 93 full‐term infants with neonatal hyperbilirubinaemia, 46 of which were treated by exchange transfusion. At examination between 2 and 2 1/2 years of age no differences with regard to neurological abnormalities or development could be demonstrated between the two groups. No definite signs of kernicterus were present in any case. One child with congenital hypothyroidism showed a minor disturbance in coordination not apparent until the age of 4 years.
Venous Pressure in the First Hour of Life and Its Relationship to Placental Transfusion
Authors: JEGIER W. , BLANKENSHIP W. , LIND J. 
Published: January 2008

SUMMARYCentral and portal venous pressure in the first hour of life was studied in 24 normal, full‐term, newborn infants with varying amounts of placental transfusion. A gradient between the portal pressure and the central venous pressure was demonstrated in the 11 out of 14 infants. The pressure in the central venous system varied with the amount of placental transfusion, whereas the pressure existing distal to the ductus venosus was independent ofthe blood volume during the first hour of life. The central pressure observed in infants that received a large amount of placental transfusion (ten infants) ranged between 0 mm Hg and 10 mm Hg with a mean of 5.7 mm Hg. The pressure in the group receiving a lesser amount of placental transfusion (seven infants) ranged between 1.5 mm Hg and 5 mm Hg with a mean of 1.7 mm Hg. Pressures obtained distal to the ductus venosus ranged from 4 mm Hg to 11 mm Hg with a mean of 7.7 mm Hg. The presence of a narrow ductus venosus channel contributes to the existence of this gradient.Data obtained from dilution curves recorded from right atrial and portal vein injections suggested that little or no blood flows through the ductus venosus during the first hours of life.
Basophil Leucocytes and Heparinoid Substances in Diabetes Mellitus
Authors: ENGLESON GUNNAR , LINDBERG TOR 
Published: January 2008

SummaryThe present investigation showed a reduction in the content of heparinoid substances in the blood in the late vascular complications of diabetes. This finding suggests the occurrence, in diabetic angiopathy, of a disorder pathogenetically similar to that in atherosclerosis. The decrease found in the amount of heparinoid substances in the blood cannot be explained by a change in the number of basophil leucocytes, which are normal in diabetes mellitus. The number of cases, however, is not large and further investigations are in progress.
Red Cell Triiodothyronine Uptake as a Measure of Thyroid Function in Mongolism
Authors: SPINELLI‐RESSI FRANCO , BERGONZI FEDERICO 
Published: January 2008

SummaryThe red cell triiodothyronine uptake was performed in a group of 25 mongoloid children, in order to assess the applicability of this method in evaluating the thyroid status in mongolism. Our studies indicate that the mean T3 uptake in mongoloids is increased. However in 11 out of 25 mongoloids studied by us the uptake values fall within the normal range, so that the test cannot be considered characteristic in mongolism. In all the mongoloid children the BMR was normal. On the contrary, in seven cases with an increased red cell T3 uptake, a decrease of total serum protein and albumin was found. Since it is known that abnormalities of plasma proteins influence the red cell T3 uptake, the hypothesis that some plasma factor(s) is responsible for the increased uptake of labelled triiodothyronine in mongolism is suggested. Whatever the extrathyroid factor(s) responsible for the increased red cell T3 uptake is, the technique is not a valuable tool in assessing the thyroid function in mongolism.
Late Electroencephalographic Findings after Recovery from Tuberculous Meningitis
Authors: KAUHTIO JYRKI , DONNER MÄRTA , WASZ‐HÖCKERT OLE 
Published: January 2008

SummaryEighty five children and young persons cured of tuberculous meningitis were reexamined by EEG 6—12 1/2 years after the onset of the disease.Moderate or severe EEG changes were seen in 50 cases, i.e. 59 per cent. The most frequent abnormality found was general dysrhythmia (29 cases) combined with focal abnormalities in 9 cases. Focal abnormalities were seen in the records of altogether 14 former patients. Of these, 9 had convulsions. Repeated EEG examinations were made in 15 cases. Seven of these showed improvement and 1 progression of the disturbances. Abnormal EEGs were seen most frequently among the youngest patients (0—3 years), among patients with severe symptoms on admission and among patients treated with cortisone.Correlation was also found between EEG changes and other sequelae: convulsions, neurological disorders, mental sub‐normality, behaviour disturbances and intracranial calcifications. There were no correlations between EEG abnormalities and late ophthalmological and otological sequelae.
Spontaneous Pneumothorax in the Newborn
Authors: MALAN A. F. , HEESE H. de V. 
Published: January 2008

SummaryThe obstetrical, clinical, radiological and biochemical findings in 7 cases of spontaneous pneumothorax of the newborn are presented. All the infants survived. Attention i s drawn to the presence of a chest bulge as a prominent physical sign in the diagnosis of pneumothorax. The significance of irritability in association with a rapid respiratory rate is discussed.
Ataxia‐Telangiectasia
Authors: SMEBY BJARNE 
Published: January 2008

SummaryFive cases of ataxia‐telangiectasia are reported. In 4 cases, there is no parental consanguinity. In the other case the parents are unknown. The maternal grandfather of one of the patients hadtelangiectasiae in the scalp, face and ears, but no ataxia and the γA‐globulin content in the serum was normal. There was no known case of ataxia in any of the families. All of the patients had had bronchitis, but only 3 of them had been particularly susceptible to respiratory infections. The growth was retarded in all. None of them presented deformities of the feet or kyphoscoliosis.Only in one patient was the motor development retarded during the first year of life, in the remaining the disturbance of the psychomotor development appeared in the form of ataxia in the course of the second or third year of life when the patients started to walk.One patient developed telangiectasiae at 2‐3 years of age, the others a t 5‐7 years of age. Patches of poor pigmentation of the skin in the fa03 were present in 4 patients. Choreoathetotic movements and a tendency to turn the eyes upwards when focusing was observed in 4 cases.The sensibility was normal in all cases. The deep reflexes were normal in one case and impaired in four. In the latter normal reflexes had been demonstrated at an earlier age. Intelligence fell within the lower limits of normality in all patients. No definite progressive impairment was demonstrable.The EEG was normal in 2 cases. In one patient a moderate general cerebral dysrhythmia was found, most marked over the right temporal region but no epileptogenic activity. I n another a focus was registered in the left temporal region. One patient had not been submitted to EEG.Paper chromatography of the urine revealed a normal amino acid pattern in 4 cases, the 5th was not examined.
The Surgical Management of Myelomeningocele with a Preliminary Report of 31 Cases
Authors: ANDERSSON HUGO , CARLSSON CARL‐AXEL 
Published: January 2008

SummaryA case material of 31 myelomeningoceles from 1963–64 is presented. The two main principles for treatment were: no selection of candidates for surgery and surgery as early as possible. The rate of accompanying hydrocephalus amenable to treatment was 79 %. The total survival rate was 78 %Earlier communications on the subject are discussed and in view of these and our own experiences the following conclusions are drawn:1. The potential risk for future mental retardation in a new‐born with hydrocephalus cannot be regarded as a conbraindication for surgery.2. The existence or extent of paralysis of legs and/or sphincters are no contraindications for surgery.3. Contraindicating factors of social nature cannot be accepted in a civilized country.4. Early operation of myelomeningocele probably decreases the mortality and morbidity. The operative procedure is technically easier and the possibility of further damage to the neural elements is decreased.5. An effort should be made to establish communication between the open central canal and spinal subarachnoid space.
Respiratory Syncytial Virus An Outbreak of Acute Respiratory Illnesses in a Home for Infants
Authors: STERNER GÖRAN , WOLONTIS SIGVARD , BLOTH BJÖRN , HEVESY GEORG DE 
Published: January 2008

SummaryA report is given of an outbreak of acute respiratory illness in a home for infants in Stockholm. Respiratory syncytial (RX) virus was recovered from nasopharyngeal and/or throat swabs from 13 out of 15 infants (1–13 months old). Complement fixation (CF) tests against RS antigen showed at least 4‐fold rises of antibody titre in 7 out of 15 paired sera, including sera from two infants, from whom no virus was isolated. There was no rise in CF antibody titre against adenovirus, influenza A and B, parainfluenza 1, 2 and 3, mumps or herpes simplex antigens. RS virus was recovered 2 days before the onset of illness as well as 9 days afterwards. The incubation period was estimated to be from 3 to 5 days.All infants living in the home fell ill during a period from April 4 to April 30, 1964. Two‐thirds of the infants had febrile nasopharyngitis with cough and one‐third had symptoms and signs from the lower parts of the respiratory tract. Two infants had bronchopneumonia and two others were critically ill in bronchiolitis. All infants survived.
Acute Respiratory Illness with Mycoplasma Pneumoniae An Outbreak in a Home for Children
Authors: STERNER GÖRAN , HEVESY GEORG DE , TUNEVALL GÖSTA , WOLONTIS SIGVARD 
Published: January 2008

SummaryAn outbreak of acute respiratory illness, in a few cases combined with primary atypical pneumonia (P.A.P.), occurred in August‐October 1964 in a home for children in Stockholm. Seventeen out of 22 children (age 1–12 years) fell ill during the observation period, four of them twice.By using a battery of antigens (viruses, Mycoplasma pneumoniae (MP) and bacterial antigens) in a serological study on paired sera, it was found that nine children developed a significant rise of CF antibodies against MP only, two had rise of antipneumolysin titre only, whereas one child had rising antibody titres against adenovirus and MP as well as against Haemophilus influenzae. MP was cultivated from the throat in four cases.Of the 15 children with proved or probable fresh MP infection two were healthy, four had an afebrile mild upper respiratory illness, six had acute respiratory illness with fever, mostly of short duration, and without clinical signs of pneumonia. In three cases, all above 5 years of age, P.A.P. was demonstrated.
Experiences with Human Growth Hormone in Pituitary Dwarfism
Authors: SEIP M. , TRYGSTAD O. 
Published: January 2008

SummaryExperiences with HGH treatment of twelve hypopituitary dwarfs for periods varying from 6 to 41 months are reported.All the patients were considered to have hypopituitarism from birth, four of them of the hereditary type, four possibly due to traumatic birth or neonatal asphyxia, and four from an unknown cause. In six patients detailed information concerning growth during the first year of life could be obtained. All of these patients had a degree of growth retardation before one year of age. We consider this to be the rule rather than the exception in pituitary dwarfism.The most important diagnostic evidence was a marked degree of growth retardation accompanied by a pronounced delay in skeletal maturation, and, in most cases, signs of secondary hypothyroidism, increased insulin sensitivity, and a poor response to metopirone administration. None of the patients who had passed the normal age of puberty had matured sexually.All twelve patients responded well to HGH therapy. During the first year of treatment the average height increment was 10 cm (“catch‐up” growth). With continued treatment a normal rate of growth, about 6 cm/year, was obtained. There was no disproportionate acceleration of skeletal maturation in any of the patients. None of them has so far become resistant to HGH administration. The oldest patient has reached normal height. Whether this will be possible not only in the moderately severe, but also in the most severe cases of pituitary dwarfism, can not yet be stated.The possibility of using human gonadotrophic hormones in an attempt to produce sexual maturation in these patients is discussed briefly.