bluuebunny/crossref_metadata_2025_split huggingface dataset:
Anti‐Wound Dehiscence and Antibacterial Dressing with Highly Efficient Self‐Healing Feature for Guided Bone Regeneration Wound Closure
Authors: Xue Shenghao , Tang Ning , Zhou Cheng , Fang Shuobo , Haick Hossam , Sun Jiao , Wu Xueying 
Published: February 2024

AbstractGuided bone regeneration (GBR) is a well‐established technique for preserving and enhancing alveolar ridge structures. Success in GBR relies on fulfilling the Primary wound closure, Angiogenesis, Space maintenance, and Stability (PASS) principles. Conventional methods, involving titanium meshes and sutures, have drawbacks, including the need for secondary removal and customization challenges. To address these issues, an innovative multifunctional GBR dressing (MGD) based on self‐healing elastomer (PUIDS) is introduced. MGD provides sutureless wound closure, prevents food particle accumulation, and maintains a stable environment for bone growth. It offers biocompatibility, bactericidal properties, and effectiveness in an oral GBR model. In summary, MGD provides a reliable, stable osteogenic environment for GBR, aligning with PASS principles and promoting superior post‐surgery bone regeneration.
Active Anchoring Stimuli‐Responsive Nano‐Craft to Relieve Pulmonary Vasoconstriction by Targeting Smooth Muscle Cell for Hypoxic Pulmonary Hypertension Treatment
Authors: Li Mingxing , Shang Xuwei , Lou Haiya , Wang Zixu , Xiang Shanshan , Qiu Yihe , Hu Fuqiang , Yu Fangying , Yuan Hong 
Published: February 2024

AbstractRecently, nanotechnology‐based drug delivery platforms in treating pulmonary arterial hypertension (PAH) have gradually emerged. However, large mechanical stress and shear stress in blood vessels greatly affect the retention of nanopreparative materials at lesion sites, severely limiting nanotechnology‐based drug delivery. Herein, a stimuli‐responsive nanocraft is rationally designed by actively anchoring E‐selectin overexpressed on pulmonary arterial endothelial cells (PAECs), under hypoxic conditions, allowing effective accumulation and retention of the drug at the lesion site. Briefly, a nitrobenzene group is incorporated into the framework of a nanocarrier, and then it is simultaneously linked with chitosan. Additionally, the surface of the nanocarrier with sialic acid (SA) and encapsulated the clinically used drug ambrisentan (Am), which enables the anchoring of E‐selectin and subsequent drug delivery is modifed. This system facilitates intercellular transport to pulmonary artery smooth muscle cells (PASMCs) when targeting PAECs and specifically responds to a reductive hypoxic microenvironment with elevated nitroreductase in PASMCs. Moreover, compared with free Am, nanoencapsulation and SA‐PEG2000‐NH2 prolong the blood circulation time, achieving better therapeutic outcomes in preventing vascular remodeling and reversing systolic dysfunction. The originality and contribution of this work reveal the promising value of this pulmonary arterial anchoring stimuli‐responsive nanocraft as a novel therapeutic strategy for satisfactory PAH treatment.
Double‐Layer Asymmetric Porous Mesh with Dynamic Mechanical Support Properties Enables Efficient Single‐Stage Repair of Contaminated Abdominal Wall Defect
Authors: Tang Fuxin , Miao Dongtian , Huang Rongkang , Zheng Bingna , Yu Yang , Ma Pengwei , Peng Binying , Li Yong , Wang Hui , Wu Dingcai 
Published: February 2024

AbstractContamination tolerance and long‐term mechanical support are the two critical properties of meshes for contaminated abdominal wall defect repair. However, biological meshes with excellent pollution tolerance fail to provide bio‐adaptive long‐term mechanical support due to their rapid degradation. Here, a novel double‐layer asymmetric porous mesh (SIS/PVA‐EXO) is designed by simple and efficient in situ freeze–thaw of sticky polyvinyl alcohol (PVA) solution on the loosely porous surface of small intestinal submucosal decellularized matrix (SIS), which can successfully repair the contaminated abdominal wall defect with bio‐adaptive dynamic mechanical support through only single‐stage surgery. The exosome‐loaded degradable loosely porous SIS layer accelerates the tissue healing; meanwhile, the exosome‐loaded densely porous PVA layer can maintain long‐term mechanical support without any abdominal adhesion. In addition, the tensile strength and strain at break of SIS/PVA‐EXO mesh change gradually from 0.37 MPa and 210% to 0.10 MPa and 385% with the degradation of SIS layer. This unique performance can dynamically adapt to the variable mechanical demands during different periods of contaminated abdominal wall reconstruction. As a result, this SIS/PVA‐EXO mesh shows an attractive prospect in the treatment of contaminated abdominal wall defect without recurrence by integrating local immune regulation, tissue remodeling, and dynamic mechanical supporting.
Unexpected Energy Applications of Ionic Liquids
Authors: Matuszek Karolina , Piper Samantha L. , Brzęczek‐Szafran Alina , Roy Binayak , Saher Saliha , Pringle Jennifer M. , MacFarlane Douglas R. 
Published: February 2024

AbstractIonic liquids and their various analogues are without doubt the scientific sensation of the last few decades, paving the way to a more sustainable society. Their versatile suite of properties, originating from an almost inconceivably large number of possible cation and anion combinations, allows tuning of the structure to serve a desired purpose. Ionic liquids hence offer a myriad of useful applications from solvents to catalysts, through to lubricants, gas absorbers, and azeotrope breakers. The purpose of this review is to explore the more unexpected of these applications, particularly in the energy space. It guides the reader through the application of ionic liquids and their analogues as i) phase change materials for thermal energy storage, ii) organic ionic plastic crystals, which have been studied as battery electrolytes and in gas separation, iii) key components in the nitrogen reduction reaction for sustainable ammonia generation, iv) as electrolytes in aluminum‐ion batteries, and v) in other emerging technologies. It is concluded that there is tremendous scope for further optimizing and tuning of the ionic liquid in its task, subject to sustainability imperatives in line with current global priorities, assisted by artificial intelligence.
Optical Crosstalk Suppression in High‐Resolution Quantum Dot Light‐Emitting Devices
Authors: Zheng Yueting , Lin Lihua , Hu Hailong , Guo Tailiang , Li Fushan 
Published: February 2024

AbstractHigh‐resolution (HR) displays are in much demand as metaverse makes near‐eye displays the most important equipment in recent years. Based on wave optics, a microscale optical crosstalk model for HR display devices is proposed. It is indicated that the pixel pattern will be distorted over long‐distance transmission in light‐emitting devices with inner periodic microstructure, and the optical distortion is related to the size of pixels and the distance from the emitting layer to the outlet. A bottom emissive HR red quantum dot light‐emitting diode (QLED) array is introduced to confirm the model and a top emission scheme is provided to effectively reduce the transmission distance and suppress the pixel distortion. Optical‐crosstalk‐free pixels are finally achieved by adopting the optimized top‐emission cathode thickness of 30 nm. This study provides a direction for realizing high‐quality and high‐resolution micro‐displays.
Full‐Spectral Response Perovskite Solar Cells Through Integration of MXene Modified Near‐Infrared Organic Heterojunction and Waveguide‐Structure Quantum‐Cutting Down‐Converter
Authors: Shi Zhichong , Zhou Donglei , Zhuang Xinmeng , Xu Wen , Liu Shuainan , Liao Yuqing , Jia Pingye , Pan Gencai , Liu Wei , Zhu Jichun , Song Hongwei 
Published: February 2024

AbstractTo date, lead‐based perovskite solar cells (PSCs) are optimized to the extreme and achieved an efficiency of as much as 26.1%. Expanding the spectral response is one of the most effective methods for achieving further efficiency breakthroughs. In this study, integrated PSCs are constructed by combining near‐infrared (NIR) organic bulk heterojunctions (BHJs) with perovskite layers to broaden the NIR spectral response range. Ultraviolet (UV)‐plasma‐treated MXene Nb2CTx ‐ quantum dots (QDs) are introduced to promote exciton dissociation inside the BHJ and to solve the problems of severe nonradiative exciton recombination and open‐circuit voltage (Voc) loss in IPSCs. In addition, CsPbCl3:Yb(7%),Li(2%) QDs with quantum‐cutting emission and photoluminescence quantum yield of up to 170% act as down‐converters to enhance the utilization of UV light. MgF2 is deposited on the quantum‐cutting layer to construct a waveguide‐structured anti‐reflection layer and further increase UV photon utilization. The champion device achieves superior photoelectric performance with a photoelectric conversion efficiency of 24.3%, Voc of 1.17 V, a short circuit current of 26.65 mA cm−2, and a fill factor of 77.95%. Champion devices exhibit excellent UV and long‐term stability. This study provides an instructive strategy for fabricating high‐performance full‐spectral‐response PSCs.
An In Situ Gelled Polymer Electrolyte to Stabilize Lithium–Air Batteries
Authors: Li Zi‐Wei , Liang Yu‐Long , Wang Jin , Yan Jun‐Min , Liu Jian‐Wei , Huang Gang , Liu Tong , Zhang Xin‐Bo 
Published: February 2024

AbstractGel polymer‐based lithium batteries exhibit a unique combination of advantageous properties, including the favorable interfacial contact characteristic of liquid‐state batteries and the inherent stability of solid‐state batteries. For Li–air batteries operated in the semi‐open atmosphere, implementing in situ synthesized gel polymer electrolytes (GPEs) is effective in mitigating the environment‐induced challenges. In this study, a dimethyl sulfoxide (DMSO)‐based GPE in situ initiated by the toluene‐2,4‐diisocyanate (TDI) and 1,4‐benzenediboronic acid (BDBA) is designed to enable the stable operation of lithium–air batteries. The integration of in situ polymerization and polyvinyl alcohol's functional group engineering not only brings benefits to the interfacial contact and electrochemical stability of the battery but also mitigates the moisture sensitivity and volatility of the DMSO electrolyte in the ambient environment. In addition, the GPE can promote the formation of a robust protection film on the lithium surface. As a result, the designed GPE makes the batteries fully leverage their outstanding cycling stability in the ambient environment (241 cycles at 500 mA g−1 and 1000 mAh g−1). Moreover, an optimized Li–air pouch cell structure incorporating the GPE achieves a boasted energy density of 757.5 Wh kg−1, providing a significant technical pathway to bring Li–O2 batteries to practical Li–air batteries.
Continuous conveying and mixing characteristics of high‐viscosity materials under acoustic vibration excitation
Authors: Zhan Xiaobin , Ye Binhuan , Li Biran , Shi Tielin 
Published: February 2024

AbstractInvestigating the conveying and mixing characteristics of high‐viscosity fluids in an inclined flow channel under the excitation of acoustic vibration using computational fluid dynamics methods. As the intensity of the acoustic vibration excitation increases, the free surface of the liquid transitions from generating Faraday waves to generating disordered jets. Continued increase in the amplitude leads to the liquid filling most of the vessel space, causing a blockage. However, slowly increasing the amplitude alleviates the blockage phenomenon. When high‐viscosity materials are subjected to high‐intensity acoustic vibration, the flow field is dominated by shear flow, which is accompanied by efficient stretching and folding. Changing the amplitude or frequency alone can cause blockage, and increasing the frequency of vibration excitation alone will not alleviate the blockage. Instead, increasing the amplitude can generate more mixing‐promoting reflux, effectively relieving blockage while maintaining stable conveying capacity.
Hematologic malignancies in Li–Fraumeni syndrome: A case report
Authors: Bundrant Bethany , Gerstein Yoheved , Arun Banu , DiNardo Courtney D. 
Published: February 2024

AbstractLi–Fraumeni syndrome (LFS) is a rare syndrome characterized by an increased lifetime risk of cancer development in multiple organ systems, typically caused by de novo or inherited germline pathogenic variants in the tumor suppressor TP53 gene. LFS is more classically associated with solid tumors; however, it is also associated with hematologic malignancies such as therapy‐related acute myeloid leukemia (AML). We present the case of a female patient with a strong family and personal history of cancer who presented to our institution with therapy‐related AML with next‐generation sequencing showing a pathogenic TP53 mutation. She received several lines of systemic therapy and underwent stem cell transplant using her adult daughter as a haploidentical donor after achieving minimal residual disease (MRD). Her posttransplant bone marrow evaluations demonstrated persistence of the same pathogenic TP53 mutation despite ongoing clinical remission with full donor engraftment and negative MRD. Genetic testing was performed which confirmed the germline origin of the TP53 pathogenic variant in the patient. The patient's adult donor daughter was also identified to have the same pathogenic variant in TP53 consistent with LFS. The presented case highlights the need for increased awareness of LFS in the adult hematologic community, particularly for patients undergoing evaluation for stem cell transplant.
From such great heights: The effects of substrate height and the perception of risk on lemur locomotor mechanics
Authors: Schapker Nicole M. , Janisch Judith , Myers Lydia C. , Phelps Taylor , Shapiro Liza J. , Young Jesse W. 
Published: February 2024

AbstractObjectivesAn accident during arboreal locomotion can lead to risky falls, but it remains unclear that the extent to which primates, as adept arborealists, change their locomotion in response to the perceived risk of moving on high supports in the tree canopy. By using more stable forms of locomotion on higher substrates, primates might avoid potentially fatal consequences.Materials and MethodsUsing high‐speed cameras, we recorded the quadrupedal locomotion of four wild lemur species—Eulemur rubriventer, Eulemur rufifrons, Hapalemur aureus, and Lemur catta (N = 113 total strides). We quantified the height, diameter, and angular orientation of locomotor supports using remote sensors and tested the influence of support parameters on gait kinematics, specifically predicting that in response to increasing substrate height, lemurs would decrease speed and stride frequency, but increase stride length and the mean number of supporting limbs.ResultsLemurs did not adjust stride frequency on substrates of varying height. Adjustments to speed, stride length, and the mean number of supporting limbs in response to varying height often ran counter to predictions. Only E. rubriventer decreased speed and increased the mean number of supporting limbs on higher substrates.DiscussionResults suggest that quadrupedal walking is a relatively safe form of locomotion for lemurs, requiring subtle changes in gait to increase stability on higher—that is, potentially riskier—substrates. Continued investigation of the impact of height on locomotion will be important to determine how animals assess risk in their environment and how they choose to use this information to move more safely.
Medication utilization for patients with chronic rhinosinusitis with nasal polyposis and asthma in 12 months pre‐ and post‐dupilumab initiation
Authors: Garvey Emily , Naimi Bita , Duffy Alexander , Kahn Chase , Farquhar Douglas , Rosen Marc , Rabinowitz Mindy , Evertz Damaris Pena , Most Jessica , Toskala Elina , Nyquist Gurston G. 
Published: February 2024

Key points
This study examines the impact of dupilumab on medication use for chronic rhinosinusitis with nasal polyposis (CRSwNP) and asthma patients.
Patients on dupilumab had a reduction in oral/inhaled/topical steroids, antibiotics, and leukotriene receptor antagonists (LTRAs).
The reduction in medication use had no impact on total polyp or SNOT‐22 scores.
Three‐dimensional simulation of dripping and jetting phenomenon in a flow‐focusing geometry
Authors: Biswas Saikat , Pattader Partho S. G. , Mandal Tapas K. 
Published: February 2024

Abstract3D simulations have been achieved on a flow‐focusing geometry employing the VOF method to study the consequence of viscosity, surface tension, wettability, and geometry on drop generation for the dripping regime. Here the dispersed phase is the PDMS oil (polydimethylsiloxane), and the continuous phase is the water. Simulations were performed at different oil‐to‐water viscosity ratios
of 3, 12, 27, and 50. The interfacial tension between PDMS oil and water is 0.0118 N/m. It has been abridged to 0.008 N/m, 0.005 N/m, and 0.002 N/m, and simulations were performed. The walls of the microchannel are considered to be PMMA surfaces. The contact angle of an oil droplet on the PMMA surface in the presence of water is 140°. The effect of wettability was shown at various contact angles (angle created by water droplet on the PMMA surface in the presence of oil) of 0°, 40°, 90°, 135° and 180°. The frequency of droplet generation (1/s), non‐dimensional droplet length (L/Wc), droplet volume (nl), and droplet velocity (m/s) have been calculated for each of the cases. A flow pattern map has been industrialized classifying the dripping and jetting regimes. A comparison between normal geometry and two constricted geometries (having different orifice lengths) based on the frequency of droplet, non‐dimensional drop length, drop volume, and drop velocity has been made for both dripping and jetting regimes. Prediction of simulated non‐dimensional droplet length has also been made using dimensional analysis.
The production of bacterial cellulose from coconut water and its application as a green photocatalyst composite membrane
Authors: Mutiara Tintin , Jingga Ajeng Catra , Widya Amanda Zulfa 
Published: February 2024

AbstractIn this research work, bacterial cellulose was produced from the fermentation of coconut water and incubated for 4, 5, and 6 days. The bacterial cellulose membrane was utilized as immobilized silver nanoparticles (AgNPs). A green photocatalyst membrane was prepared by reducing silver ions in the bacterial cellulose matrix structure using local fruit extracts, tomatoes, Citrus hystrix fruit, and mangosteen peel as a reducing agent. The composite was dried in the oven to obtain a more durable fixed structure. The properties of produced bacterial cellulose were determined by measuring the thickness, water retention capacity (WRC), cellulose content, and swelling. The functional group and crystallinity index of bacterial cellulose were observed by FTIR and XRD instrument analysis. The SEM EDX analysis confirms that the silver ions were successfully reduced in the BC matrix, and the UV–Vis spectrum showed that the composite membrane has the ability to degrade the methylene blue solution under sunlight irradiation. The maximum degradation efficiency of the composite membrane against 5 ppm methylene blue solution was achieved by the composite membrane reduced by tomatoes, with a value of 93%. This result proved that the composite membrane produced in this research has excellent capabilities as a green photocatalyst for degrading wastewater containing dye pollutants.
Prediction of the potential distribution area of Spodoptera frugiperda and its parasitic wasp, Trichogramma pretiosum
Authors: Jia Jingjing , Wang Aqiang , Peng Sihua , Lian Yuyang , Wu Qianxing , Lin Zhufeng , Zhang Qiongkuan , Ji Xuncong 
Published: February 2024

AbstractSpodoptera frugiperda is a migratory agricultural pest with fast‐spreading speed, long migration distance, and wide host range, which seriously threatens the safety of economic crops. To predict the trends of S. frugiperda and its parasitoid wasp Trichogramma pretiosum in their habitats under current and future climatic conditions, based on MaxEnt model and geographic distribution data of their historical occurrence, we project the feasibility of introducing T. pretiosum to control S. frugiperda by evaluating on their potential global distribution. The results show that, under the current greenhouse gas concentration, the potential distribution area of S. frugiperda is concentrated in 50° N‐30° S, with a total area of 1.74 × 106 km2, and the potential distribution area of T. pretiosum in the whole world is 2.91 × 106 km2. The suitable areas of T. pretiosum cover almost all the suitable areas of S. frugiperda, which indicates that T. pretiosum can be introduced to control S. frugiperda. The results of this study can provide a theoretical basis for the monitoring and early warning of S. frugiperda and the use of T. pretiosum to control S. frugiperda.
Gastroschisis prevalence patterns in 27 surveillance programs from 24 countries, International Clearinghouse for Birth Defects Surveillance and Research, 1980–2017
Authors: Feldkamp Marcia L. , Canfield Mark A. , Krikov Sergey , Prieto‐Merino David , Šípek Antonin , LeLong Nathalie , Amar Emmanuelle , Rissmann Anke , Csaky‐Szunyogh Melinda , Tagliabue Giovanna , Pierini Anna , Gatt Miriam , Bergman Jorieke E. H. , Szabova Elena , Bermejo‐Sánchez Eva , Tucker David , Dastgiri Saeed , Bidondo María Paz , Canessa Aurora , Zarante Ignacio , Hurtado‐Villa Paula , Martinez Laura , Mutchinick Osvaldo M. , Camelo Jorge Lopez , Benavides‐Lara Adriana , Thomas Mary Ann , Liu Shiliang , Nembhard Wendy N. , Gray Elizabeth B. , Nance Amy E. , Mastroiacovo Pierpaolo , Botto Lorenzo D. 
Published: February 2024

AbstractBackgroundGastroschisis is a serious birth defect with midgut prolapse into the amniotic cavity. The objectives of this study were to evaluate the prevalence and time trends of gastroschisis among programs in the International Clearinghouse for Birth Defects Surveillance and Research (ICBDSR), focusing on regional variations and maternal age changes in the population.MethodsWe analyzed data on births from 1980 to 2017 from 27 ICBDSR member programs, representing 24 countries and three regions (Europe+ (includes Iran), Latin America, North America). Cases were identified using diagnostic codes (i.e., 756.7, 756.71, or Q79.3). We excluded cases of amniotic band syndrome, limb–body wall defect, and ruptured omphalocele. Programs provided annual counts for gastroschisis cases (live births, stillbirths, and legally permitted pregnancy terminations for fetal anomalies) and source population (live births, stillbirths), by maternal age.ResultsOverall, gastroschisis occurred in 1 of every 3268 births (3.06 per 10,000 births; 95% confidence intervals [CI]: 3.01, 3.11), with marked regional variation. European+ prevalence was 1.49 (95%CI: 1.44, 1.55), Latin American 3.80 (95%CI: 3.69, 3.92) and North American 4.32 (95%CI: 4.22, 4.42). A statistically significant increasing time trend was observed among six European+, four Latin American, and four North American programs. Women <20 years of age had the highest prevalence in all programs except the Slovak Republic.ConclusionsGastroschisis prevalence increased over time in 61% of participating programs, and the highest increase in prevalence was observed among the youngest women. Additional inquiry will help to assess the impact of the changing maternal age proportions in the birth population on gastroschisis prevalence.