bluuebunny/crossref_metadata_2025_split huggingface dataset:
Impact of endogenous analgesia triggered by acupuncture, stress, or noxious stimulation on REM sleep-deprived rats
Authors: Sardi Natalia F. , Natume Priscila , Watanabe Thainá , Pescador Ana Carolina , Torres-Chavez Karla E. , Tobaldini Glaucia , Fischer Luana 
Published: February 2024

AbstractPoor sleep increases pain, at least in part, by disrupting endogenous pain modulation. However, the efficacy of endogenous analgesia in sleep-deprived subjects has never been tested. To assess this issue, we chose three different ways of triggering endogenous analgesia: (1) acupuncture, (2) acute stress, and (3) noxious stimulation, and compared their ability to decrease the pronociceptive effect induced by REM-SD (Rapid Eye Movement Sleep Deprivation) with that to decrease inflammatory hyperalgesia in the classical carrageenan model. First, we tested the ability of REM-SD to worsen carrageenan-induced hyperalgesia: A low dose of carrageenan (30 µg) in sleep-deprived Wistar rats resulted in a potentiated hyperalgesic effect that was more intense and longer-lasting than that induced by a higher standard dose of carrageenan (100 µg) or by REM-SD alone. Then, we found that (1) acupuncture, performed at ST36, completely reversed the pronociceptive effect induced by REM-SD or by carrageenan; (2) immobilization stress completely reversed the pronociceptive effect of REM-SD, while transiently inhibited carrageenan-induced hyperalgesia; (3) noxious stimulation of the forepaw by capsaicin also reversed the pronociceptive effect of REM-SD and persistently increased the nociceptive threshold above the baseline in carrageenan-treated animals. Therefore, acupuncture, stress, or noxious stimulation reversed the pronociceptive effect of REM-SD, while each intervention affected carrageenan-induced hyperalgesia differently. This study has shown that while sleep loss may disrupt endogenous pain modulation mechanisms, it does not prevent the activation of these mechanisms to induce analgesia in sleep-deprived individuals.
Design and Implementation of No Load, Constant and Variable Load for DC Servo Motor
Authors: Shneen Salam Waley , Dakheel Hashmia S , Abdullah Zainab B 
Published: February 2024

Simulations were conducted to improve and design an appropriate control system and obtain a model with the required development to suit the operation of the engine with constant and variable loads, which are the proposed working conditions that are suitable for many applications. The current simulation aims to build and design a model for an electric motor (DC Servo motor) and a model for a conventional controller (PID). The proposed model addresses the cases of fixed and variable loads in terms of using the controller that improves the performance of the motor’s work for different conditions. Three cases were developed to conduct the proposed tests, which included the case of no-load, fixed and variable load. Tests were conducted. Without the console and for the purpose of comparison and observation of improvement, the test was conducted with the addition of the console. The results showed system performance may improve depending on usage using traditional control systems. Performance measurement criteria are adopted for the purpose of comparison and observation of performance improvement. The criteria that are adopted are rise time and stability (steady state) in addition to the ratio of the rate of under and over-shoot. Where it can be deduced from this the possibility of using different control systems, including traditional ones, to improve performance, and they include controlling the speed of the motors, as well as controlling the effort, and the consequent effects on the subject of the study, as it deals with transient cases and changing operating conditions with more than acceptable efficiency and relatively high quality. There are four state simulation include, 1st at no load without controller: rise time equal 309.886ms , overshoot equal 44.203% and undershoot equal 9.597%.2nd at load without controller: rise time equal 216.319ms , overshoot equal 58.654% and undershoot equal 0.210%.3rd at no load with PID controller: rise time equal 1.177s , overshoot equal 0.505% and undershoot equal 1.914%.4th at load with PID controller: rise time equal 1.112s , overshoot equal 0.509% and undershoot equal 5.856%.
Hidden Behind Chronic Dyspeptic Symptoms: Post-traumatic Diaphragmatic Eventration
Authors: YILDIZ Latife Merve , CUBUKCU Mahcube 
Published: February 2024

Abstract
Diaphragmatic eventration is commonly seen following high-energy traumas, particularly due to traffic accidents and falls from significant heights. This pathology has the potential to influence both the gastrointestinal and cardiorespiratory systems, presenting with a variety of symptoms. A 45-year-old male patient, with a history of trauma from falling off a tree, sought medical attention at our clinic with dyspeptic complaints and symptoms of shortness of breath. During the physical examination, diminished sounds were detected in the right lung field, along with epigastric tenderness. For diagnostic purposes, a posteroanterior chest radiograph (CXRs) and thoracic computed tomography (CT) scan were obtained. A subsequent bronchoscopy, performed with a pulmonology consultation, revealed decreased diaphragmatic movements. Taking into account the findings, a thoracic surgery treatment plan was devised for the patient. This case report underscores the significance of considering the seldom-encountered pathology of diaphragmatic eventration in patients presenting with dyspeptic and respiratory complaints. Keeping in mind that patients with such symptoms frequently turn to family physicians, it highlights the pivotal role of a multidisciplinary primary care approach in initiating the diagnostic trajectory.
Tonsil problem and its cardiovascular aspects at present stage
Authors:   Stavropol Regional Clinical Hospital, Stavropol, 355029, Russia, Eremin M. V. , Simkhes E. V. ,   Stavropol State Medical University, Stavropol, 355017, Russia, Evsev’eva M. E. ,   Stavropol State Medical University, Stavropol, 355017, Russia, Koshel’ I. V. ,   Stavropol State Medical University, Stavropol, 355017, Russia
Published: February 2024

A comparative assessment of the characteristics of myocardial and vascular damages as well as their occurrence in patients with decompensated chronic tonsillitis (CT) sent to the hospital for planned tonsillectomy were carried out. 179 people aged 18 to 25 years were examined. Two groups were formed: group 1: patients with decompensated СT (102 people) and group 2: control – that is, persons without СТ (77 people). We used 24-hour ECG monitoring (Holter) with a set of additional diagnostic options and EchoCG to determine various characteristics of myocardial activity. The arterial wall was assessed using indicators of vascular stiffness and assessment of blood pressure balance in the vascular territories. We used hardware-diagnostic complexes DMS Advanced Technologies (Russia) and RuSkan-70P (Russia). Myocardial damage was judged by exceeding the upper limit of the permissible norm for such indicators as the number of extrasystoles per hour, the maximum rate of increase in pressure in the aorta (dP/dTmax), and the size of the heart chambers; and damage to the vascular wall was judged by similar changes for the aortic pulse wave (PWVao), aortic reverse pulse wave augmentation index (AIx ao), and ankle-brachial index (ABI). The individual profile of the main cardiovascular risk factors was also assessed. Data processing was carried out using the Statistica 10.0 software package (StatSoft Inc., USA). The results indicated the presence of a negative effect of СТ not only on the myocardium with the development of some moderate changes but also on the vascular wall. The latter violations were recorded significantly more often. Vascular disorders were characterized by increased arterial stiffness and pressure imbalance within the framework of preclinical arterio- and atherosclerosis. It is necessary to develop targeted angioprotective measures with СТ and their inclusion in the comprehensive process of managing this category of patients, including in the preoperative period. Therefore, the management of such patients should be based on the principles of effective interdisciplinary cooperation.
Impact of Plant Growth Regulators on Seed Health during Accelerated Ageing Test in Chickpea [Cicer arietinum (L.)] Seeds
Authors: Mishra Sachchida Nand , Mishra Kalpana , Mishra Namo Narayan , Para Pavan Kumar 
Published: February 2024

Background: Research was conducted to ascertain the impact of hormonal seed strengthening on seed health status under an accelerated ageing test in chickpea (Cicer arietinum L) at the state seed testing laboratory during the Rabi seasons of 2018-19 and 2019-20. Four replications of the Blotter test were performed CRD plan. As per continuous evaluation and observation, under accelerated ageing increased pathogens were observed with increased temperature and RH, the seeds treated with salicylic acid resulted with least pathogen infection while compared to other treatments. Methods: The current experiment was conducted in the state seed testing laboratory, Department of Genetics and Plant Breeding, SHUATS, Prayagraj, Uttar Pradesh, between the years of 2018 and 2020. 37 distinct treatment combinations were employed in the experiment. The seeds were placed in an accelerated ageing condition with high temperature and relative humidity. Hormonal seed strengthening is the activity of infusing PGRs into old seeds to make them fresh again with the help of PGRs (salicylic and giberellic acid) treatments into old seeds and increase the vigour index of seeds. Result: In this experiment chick pea seeds treated with combination of gibberellic acid and salicylic acid resulted in least infection of seed pathogens we can recommend these for maintaining seed health status.
Determinan Ketahanan Pangan Rumahtangga di Kabupaten Tulang Bawang Selama Pandemi Covid-19
Authors: Afifah Nurul , Prasetyaningtyas Woro Ayu 
Published: February 2024

Ketahanan pangan merupakan salah satu tujuan yang harus dipertahankan selama pandemi Covid-19. Namun kondisi perekonomian sekarang ini menyebabkan berkurangnya pendapatan masyarakat karena penurunan aktivitas usaha produktif, sehingga meningkatnya angka pengangguran dan kemiskinan. Hal ini cukup mengkhawatirkan pemerintah jika terjadi krisis pangan di masa mendatang. Kabupaten Tulang Bawang merupakan salah satu wilayah yang merasakan dampak dari pandemi Covid-19. Oleh karena itu, penelitian ini bertujuan untuk mengetahui gambaran ketahanan pangan di Kabupaten Tulang Bawang dan variabel-variabel yang mempengaruhinya. Hasil analisis regresi logistik multinomial menemukan bahwa jumlah anggota rumah tangga yang sedikit, pendidikan kepala rumah tangga yang tinggi, serta kondisi kemiskinannya tidak miskin akan meningkatkan peluang rumah tangga tersebut untuk tahan pangan.
A Novel Approach to Borehole Quality Measurement in Unconventional Drilling
Authors: Fonseca Isaac S. , Pastusek Paul , Isbell Matt , Sowers Steven , Payette Gregory , Avdeev Dmitry , Tingey Brady 
Published: February 2024

Abstract
Borehole quality is a crucial aspect of wellbore construction, impacting drilling and completion execution and long-term well reliability in terms of zonal isolation and casing integrity. However, developing key performance indicators and requirements for borehole quality has proven difficult since there are few direct measurements of borehole characteristics other than surveys.
This paper explores the use of ultra-high frequency acoustic borehole image logs and caliper measurements to develop methods to quantify effects during drilling operations, such as micro-tortuosity, salt creep, and other observed characteristics, which could prove useful in defining wellbore quality in the drilling phase. The role of the repeatable process of drilling a stand with different bottom hole assembly (BHA) designs as motorized rotary steerable systems (RSS) and conventional steerable systems (CSS) will be mapped to borehole quality impact with downhole measurements. Drilling operations and methods will be linked with the resulting borehole measurements and the relationship in terms of correlation and causality examined.
This case study documents the application of the processes and tools for vertical and lateral intervals of horizontal wells in the different basins of North America. Results of different states of drilling operations such as sliding, rotating, and reaming, drilling dysfunctions, BHA changes, drilling practices, and rock characteristics will be presented. The paper's conclusions use this approach to determine the needs and methods of wellbore quality measurement and requirements for drilling and completions and potential life of well implications.
This paper builds on the drilling mechanics process and downhole measurements to determine usable borehole quality key performance indicators that can be applied as additional wellbore quality management methods.
Field Scale Tests & Modeling to Forecast Gas Migration Rates for Pressurized Mud Cap Drilling (PMCD) Applications
Authors: Moganaradjou Yashwant , Samdani Ganesh Arunkumar , Almeida Mauricio A. , Kunju Mahendra K. , Gupta Vishwas Paul 
Published: February 2024

AbstractUnderstanding gas migration rates is a critical part of well control discipline; for PMCD significant discrepancies exist between field observations of gas migration rates and common industry estimation methods (e.g. SPE212546). The objective of this work was to study realistic field scale scenarios in a test well and develop a predictive model using the data. The model helps in simulating field scenarios and efficient planning of fluid logistics with significant economic impact. We present an industry first well scale study that demonstrates the impact of flow regime and solubility using Argon & Nitrogen on gas migration. A 5200-ft-deep vertical test-well with 9-5/8″x2-7/8″ annulus equipped with 4 downhole pressure/temperature gauges and fiber optic DTS/DAS is utilized for the field-scale experiments. Tests were conducted by injecting gas at the bottom and observing its migration in the static mud column, followed by flushing to simulate PMCD shut-in and flushing cycles. The impact of gas solubility, bottomhole pressure (BHP) and gas injection rates were studied. Nitrogen/Argon gases were used to introduce solubility differences. To estimate gas migration rates, a mathematical model was developed and calibrated with the test data. The flow regime and gas solubility in the mud were found to be the most important factors in determining gas migration rates. Flow regime transition from Cap to Taylor bubbles was observed when BHP was rapidly dropped from 3600 to 2290 psi, with a threefold increase in gas migration rates. Argon gas migration rates were ~half that of nitrogen under the same test conditions which is in line with the gas solubility differences between the two gases. The gas migration rate increased non-linearly with injection rates between 0.1 to 6 bpm. The simulation model utilized well known Cap bubble correlations along with Henry's law and was found to adequately model the test results. Reported field case histories were also modeled and the results compared well with reported gas migration rates (~0.01-0.4 ft/sec) for both water and oil-based muds. The minimum mud bullheading rate to flush gas was found to be 100 gpm (0.6 ft/sec) and was ~15 % higher than the gas migration rate; this helps in determining the minimum field required flushing rate. The gas migration model accounts for solubility in the mud, pressure in the wellbore influencing gas flow regime, and gas influx rates and predicts results in-line with observed field case histories.
Development of a Fit-For-Purpose CO2 Injection Model for Casing and Tubing Design
Authors: McMillan C. E. , Buksh N. J. , McSpadden A. R. , Trevisan R. , Howard J. A. 
Published: February 2024

Abstract
The development and application of a fit for purpose CO2 Injection Model is presented in the context of a front-end engineering design for a new Carbon Capture and Storage (CCS) project targeting a depleted gas reservoir in the North Sea. The growing trend towards long-term industrial scale CCS presents challenges for the current industry design capabilities. In conjunction with the wider CCS system design, particular engineering design and integrity assurance requirements must be addressed for the wellbore components.
An appropriate Equation of State which accounts for impurities and multi-phase flow conditions is required to predict rapid changes in fluid behavior. With a depleted gas reservoir as the storage target, early-life versus late-life wellbore conditions can be significantly different. The tubular design workflow was finalized using a CO2 Injection Model deployed via a cloud-based software platform developed in concert with the well engineering design process in an agile manner. Validation of the model was provided by comparison with benchmarks from legacy software.
Coupled with drilling and cementing conditions from the well construction phase, the resultant thermal stresses on tubulars, connections and completion components during gaseous, dense and multi-phase CO2 well operating conditions need to be accurately predicted as they can be significant. Downhole conditions can be affected by cooling from adiabatic expansion and Joule-Thomson effects across chokes, due to wellbore friction and at the sand face. Transient operations during shut-in and restart result in low design case temperatures. Low-probability survival conditions under simulated blowout or leakage scenarios require to be modeled and can result in worst-case temperature qualification requirements for wellbore equipment.
Industry work groups have proposed the GERG-2008 Equation of State as a standard model for CCS operations and well design. However, potential limitations noted in technical literature appear evident from detailed well sensitivity analysis. Potential improvements to the GERG-2008 model as well as requirements for an improved fit for purpose Equation of State are outlined.
The Outcomes of Orbital Blowout Fracture Repairment by Transconjunctival Endoscopic Technique
Authors: Ye Yunyan , Hu Feng , Kong Qiao , Li Zhiguo 
Published: February 2024

Abstract

Objectives: The purpose of this case series is to present the benefits and results of using a transconjunctival endoscopic technique to repair orbital blowout fractures.
Patients and methods: In this retrospective interventional case series, 133 patients with ocular blowout fractures were enrolled. Between January 2021 and December 2022, these patients underwent transconjunctival orbital blowout fracture repair using an endoscopic technique and a Medpor-Titanium sheet implant.
Results: This study included 133 individuals (135 eyes) with orbital blowout fractures, 129 of whom were adults and 4 of whom were pediatric patients. 63 eyes had medial wall fractures, 23 eyes had inferior wall fractures, and 49 eyes had both types of wall fractures. Preoperative eyeball enophthalmos was 2.33 mm on average. In 132 eyes, postoperative exophthalmia improved by ≥2 mm, while it improved by < 2 mm in 6 eyes. After surgery, 73 individuals' diplopia disappeared one month after surgery. 42 patients' facial paresthesia recovered one to three months following surgery. After a 6-month follow-up, 131 out of 133 cases had been cured, and 2 had improved. There was a 100% effective rate and a 95.56% cure rate.
Conclusion: This article details the results and experience of using a transconjunctival endoscopic technique to repair orbital blowout fractures. The procedure is efficient in restoring orbital structure and improving visual function, and it has a low rate of postoperative complications.
Research of Water Quality Safety of Water Source Reservoir in Water Supply Project——a case Study of Mopanshan Reservoir
Authors: Hou Xinyue , Zheng Guochen , Liu Shanshan , Zhao Wei 
Published: February 2024

Abstract
Water reservoirs play a vital role in ensuring the drinking water health of urban residents. In order to study the water quality safety of water source reservoirs in water supply projects, the physical and chemical indexes of water quality in Mopansan reservoir was analyzed. The microbial diversity, community structure characteristics were analyzed by high-throughput sequencing technology. The results showed that the main exceeding standard indexof water quality of Mopan- shan Reservoir in 2022 was total nitrogen(TN). The microbial communities in the water body and sediments in the reservoir center and before the dam were com- posed of 380 genera. The microbial diversity in sediment was higher than that in water. The influence order of water quality factors on microbial community was DO > CODcr > TN > Mn2 + > Fe2+. Potential pathogenic microorganisms were detected in water and sediment samples. Although no coliform bacteria were detected, disinfection as a water supply source was still necessary. Redundancy analysis (RDA) showed that the main water quality factors affecting microbial community structure were DO and TP in the dry season, but the pattern was not obvious in the wet season. Sodium hypochlorite has a good disinfection effect on tap water and can fully ensure water quality safety.
The value of health service-based research to health service organisations: a qualitative study with senior health service executives
Authors: Todd Angela L , Petrunoff Nicholas , Frommer Michael , Nutbeam Don 
Published: February 2024

Abstract
Background: Research evidence has had demonstrably improved health care practice and patient outcomes. However, systemic translation of evidence into practice is far from optimal. The reasons are complex, but often because research is not well aligned with health service priorities. The aim of this study was to explore the experiences and perspectives of senior health service executives on two issues: (1) the alignment between local research activity and the needs and priorities of their health services, and (2) the extent to which research is or can be integrated as part of usual health care practice.
Methods: In this qualitative study, semi-structured interviews were conducted with senior health leaders from four large health service organisations that are members of Sydney Health Partners (SHP), one of Australia’s nationally accredited research translation centres committed to accelerating the translation of research findings into evidence-based health care. Interviews were conducted between November 2022 and January 2023, and either audio-recorded and transcribed verbatim or recorded in interviewer field notes. A thematic analysis of the interview data was conducted by two researchers, using the framework method to identify common themes.
Results: Seventeen health executives were interviewed, including chief executives, directors of medical services, nursing, allied health, research, and other executive leadership roles. Responses to issue (1) included themes on re-balancing of curiosity- and priority-driven research; providing more support for research activity within health organisations; and helping health professionals and researchers discuss researchable priorities. Responses to issue (2) included identification of elements considered essential for embedding research in health care; and the need to break down silos between research and health care, as well as within health organisations.
Conclusions: Health service leaders value research but want more research that aligns with their needs and priorities. Discussions with researchers about those priorities may need some facilitation. Making research a more integrated part of health care will require strong and broad executive leadership, resources and infrastructure, and investing in capacity- and capability-building across health clinicians, managers and executive staff.