bluuebunny/crossref_metadata_2025_split huggingface dataset:
Impact of hypocalcemia on mortality in pediatric trauma patients who require transfusion
Authors: Abou Khalil Elissa , Feeney Erin , Morgan Katrina M. , Spinella Philip C. , Gaines Barbara A. , Leeper Christine M. 
Published: April 2024

BACKGROUND
Admission hypocalcemia has been associated with poor outcomes in injured adults. The impact of hypocalcemia on mortality has not been widely studied in pediatric trauma.

METHODS
A pediatric trauma center database was queried retrospectively (2013–2022) for children younger than 18 years who received blood transfusion within 24 hours of injury and had ionized calcium (iCal) level on admission. Children who received massive transfusion (>40 mL/kg) prior to hospital arrival or calcium prior to laboratory testing were excluded. Hypocalcemia was defined by the laboratory lower limit (iCal <1.00). Main outcomes were in-hospital mortality and 24-hour blood product requirements. Logistic regression analysis was performed to adjust for Injury Severity Score (ISS), admission shock index, Glasgow Coma Scale (GCS) score, and weight-adjusted total transfusion volume.

RESULTS
In total, 331 children with median (IQR) age of 7 years (2–3 years) and median (IQR) ISS 25 (14–33) were included, 32 (10%) of whom were hypocalcemic on arrival to the hospital. The hypocalcemic cohort had higher ISS (median (IQR) 30(24–36) vs. 22 (13–30)) and lower admission GCS score (median (IQR) 3 (3–12) vs. 8 (3–15)). Age, sex, race, and mechanism were not significantly different between groups. On univariate analysis, hypocalcemia was associated with increased in-hospital (56% vs. 18%; p < 0.001) and 24-hour (28% vs. 5%; p < 0.001) mortality. Children who were hypocalcemic received a median (IQR) of 22 mL/kg (7–38) more in total weight-adjusted 24-hour blood product transfusion following admission compared to the normocalcemic cohort (p = 0.005). After adjusting for ISS, shock index, GCS score, and total transfusion volume, hypocalcemia remained independently associated with increased 24-hour (odds ratio, 4.93; 95% confidence interval, 1.77–13.77; p = 0.002) and in-hospital mortality (odds ratio, 3.41; 95% confidence interval, 1.22–9.51; p = 0.019).

CONCLUSION
Hypocalcemia is independently associated with mortality and receipt of greater weight-adjusted volumes of blood product transfusion after injury in children. The benefit of timely calcium administration in pediatric trauma needs further exploration.

LEVEL OF EVIDENCE
Prognostic and Epidemiological; Level III.
Pregnancy and reproductive health in women with multiple sclerosis: an update
Authors: Houtchens Maria K. 
Published: April 2024

Purpose of review
Multiple sclerosis (MS) is a chronic immune-mediated, inflammatory, neuro-degenerative disease of the central nervous system, prevalent in women of reproductive age. Today, many women want to start a family after MS diagnosis. There are over 20 treatments for MS, and safely navigating family planning is important. We review updated information on family planning, preconception, and peri-partum considerations, and reproductive concerns in special populations with MS.

Recent findings
There are no MS-related restrictions on any available and appropriate contraceptive method in women with MS. The question of MS and pregnancy outcomes following assisted reproduction, remains somewhat unsettled. In many studies, no elevated relapse risk is confirmed regardless of the type of fertility treatment. MRI status may offer better assessment of postpartum disease stability than relapse rate alone. Ongoing effective MS treatments during fertility assistance and before pregnancy, can further reduce the relapse risk. B-cell depleting therapies are emerging as safe and effective treatments for peripartum MS patients.

Summary
Patients with MS should receive accurate support and counseling related to their reproductive options. The general outlook on pregnancy and MS remains positive. The ever-increasing therapeutic complexity of MS calls for ongoing education and updated guidance for neuroimmunology and obstetrics healthcare providers.
Cardiac Rhythm Aberrations in Subacute Sclerosing Panencephalitis: Insights From Heart Rate Variability Analysis
Authors: Viswanathan Lakshminarayanapuram Gopal , Nagaraj Bittanakurike C. , Mundlamuri Ravindranadh , Thennarasu Kandavel , Kenchaiah Raghavendra , Asranna Ajay , Nagappa Madhu , Seshagiri Doniparthi , Saini Jitender , Sinha Sanjib 
Published: April 2024

Purpose:
Subacute sclerosing panencephalitis (SSPE) is a fatal neurological disorder resulting from persistent measles virus infection within the brain. Although neurological manifestations have been well-documented, the impact of SSPE on cardiac autonomic function, assessed through heart rate variability (HRV), remains understudied.

Methods:
In this prospective single-center study conducted from January 2022 to March 2023 in Southern India, 30 consecutive SSPE patients and age- and sex-matched controls underwent electrocardiogram recordings for HRV analysis. Various HRV parameters were assessed, including time-domain metrics (SD of normal-to-normal intervals, root mean square of successive differences between normal heartbeats, percentage of successive normal interbeat intervals greater than 50 msec), SD1 and SD2 for Poincaré plot analysis, and frequency-domain metrics (low frequency %, high frequency %, low frequency:high frequency ratio).

Results:
In the study, SSPE patients exhibited markedly reduced HRV. Specifically, SD of normal-to-normal intervals (P = 0.003), percentage of successive normal interbeat intervals greater than 50 msec (P = 0.03), and SD2 (P = 0.0016) were significantly lower compared with controls. Frequency-domain analysis did not reveal significant distinctions. Correlation analysis demonstrated a negative relationship between percentage of successive normal interbeat intervals greater than 50 msec and SSPE severity (r = −0.37, P = 0.042). Heart rate variability did not significantly differ between SSPE stages or with clinical variables. The interbeat interval range showed a narrower distribution in SSPE subjects.

Conclusions:
Our study highlights the clinical relevance of HRV analysis in SSPE and autonomic dysfunction throughout the disease course underscoring its importance in SSPE. This investigation provides valuable insights into cardiac autonomic dysfunction probably because of affliction of the central autonomic networks caused by the disease process and may be a contributing factor to mortality in SSPE.
Persistent cross-species transmission systems dominate Shiga toxin-producingEscherichia coliO157:H7 epidemiology in a high incidence region: a genomic epidemiology study
Authors: Tarr Gillian A.M. , Chui Linda , Stanford Kim , Bumunang Emmanuel W. , Zaheer Rahat , Li Vincent , Freedman Stephen B. , Laing Chad R. , McAllister Tim A. 
Published: April 2024

AbstractBackgroundSeveral areas of the world suffer notably high incidence of Shiga toxin-producingEscherichia coli, among them Alberta, Canada. We assessed the impact of persistent cross-species transmission systems on the epidemiology ofE. coliO157:H7 in Alberta.MethodsWe sequenced and assembled 229E. coliO157:H7 isolates originating from collocated cattle (n=108) and human (n=121) populations from 2007-2015 in Alberta. We constructed a timed phylogeny using BEAST2 using a structured coalescent model. We then extended the tree with human isolates through 2019 (n=430) to assess the long-term disease impact of locally persistent lineages. Shiga toxin gene (stx) profile was determined for all isolates.ResultsDuring 2007 to 2015, we estimated 108 (95% HPD 104, 112) human lineages arose from cattle lineages, and 14 (95% HPD 5, 23) from other human lineages; i.e., 88.5% of human lineages arose from cattle lineages. We identified 11 persistent lineages local to Alberta, which were associated with 38.0% (95% CI 29.3%, 47.3%) of human isolates. Of 117 isolates in locally persistent lineages, 6.0% carried only the Shiga toxin genestx2aand the rest bothstx1aandstx2a. During the later period, six locally persistent lineages continued to be associated with human illness, including 74.7% (95% CI 68.3%, 80.3%) of reported cases in 2018 and 2019. Thestxprofile of isolates in locally persistent lineages shifted from the earlier period, with 51.2% encoding onlystx2a.ConclusionsOur study identified multiple locally evolving lineages transmitted between cattle and humans persistently associated withE. coliO157:H7 illnesses for up to 13 years. Of concern, there was a dramatic shift in locally persistent lineages toward strains with the more virulentstx2a-only profile. Locally persistent lineages may be a principal cause of the high incidence ofE. coliO157:H7 in locations such as Alberta and offer opportunities for understanding the disease ecology supportingE. coliO157:H7 persistence, as well as for local prevention efforts.
Supportive communication between apprentices and supervisors: development of a digital role play game
Authors: Zhang Rita Peihua , Lingard Helen , Clarke Jack , Greuter Stefan , Strazdins Lyndall , LaBond Christine , Doan Tinh 
Published: April 2024

PurposeThis paper describes the development of a digital role play game (RPG) designed to help construction apprentices to better communicate with their supervisors about issues with the potential to impact on their physical and psychological health and safety.Design/methodology/approachA participatory approach was adopted to utilise the knowledge and insights of the target users to inform the digital RPG development. Apprentices and supervisors were interviewed to identify characteristics of effective supervisor-apprentice communication, which became the RPG’s learning objectives. The scenarios constructed in the RPG were drawn from lived experiences shared by the apprentices in the interviews. During the development process, consultations were conducted with an advisory committee comprising of apprentices and supervisors to improve the realism of the RPG scenarios.FindingsThree scenarios were developed for the RPG. In each scenario, players are asked to make decisions at various interaction points about how the characters should respond to the unfolding and challenging situations. Scripts were developed for the game, which were acted out and motion captured to animate digital MetaHuman characters embedded in a virtual construction site. Two example situations are introduced in this paper to illustrate the development process.Originality/valueTo our knowledge, the RPG introduced is one of the first applications of digital game-based training in the construction industry. The adoption of a participatory design approach ensures that the game content relates to real-world experiences. The digital RPG is highly interactive and engaging in nature and presents a novel approach to developing “soft” skills in construction.
Exploring and evaluating the index for interdisciplinary breakthrough innovation detection
Authors: Wang Zhongyi , Qiao Xueyao , Chen Jing , Li Lina , Zhang Haoxuan , Ding Junhua , Chen Haihua 
Published: April 2024

Purpose
This study aims to establish a reliable index to identify interdisciplinary breakthrough innovation effectively. We constructed a new index, the DDiv index, for this purpose.

Design/methodology/approach
The DDiv index incorporates the degree of interdisciplinarity in the breakthrough index. To validate the index, a data set combining the publication records and citations of Nobel Prize laureates was divided into experimental and control groups. The validation methods included sensitivity analysis, correlation analysis and effectiveness analysis.

Findings
The sensitivity analysis demonstrated the DDiv index’s ability to differentiate interdisciplinary breakthrough papers from various categories of papers. This index not only retains the strengths of the existing index in identifying breakthrough innovation but also captures interdisciplinary characteristics. The correlation analysis revealed a significant correlation (correlation coefficient = 0.555) between the interdisciplinary attributes of scientific research and the occurrence of breakthrough innovation. The effectiveness analysis showed that the DDiv index reached the highest prediction accuracy of 0.8. Furthermore, the DDiv index outperforms the traditional DI index in terms of accuracy when it comes to identifying interdisciplinary breakthrough innovation.

Originality/value
This study proposed a practical and effective index that combines interdisciplinary and disruptive dimensions for detecting interdisciplinary breakthrough innovation. The identification and measurement of interdisciplinary breakthrough innovation play a crucial role in facilitating the integration of multidisciplinary knowledge, thereby accelerating the scientific breakthrough process.
Extended (3 + 1)-dimensional Kairat-II and Kairat-X equations: Painlevé integrability, multiple soliton solutions, lump solutions, and breather wave solutions
Authors: Wazwaz Abdul-Majid 
Published: April 2024

Purpose
This study aims to investigate two newly developed (3 + 1)-dimensional Kairat-II and Kairat-X equations that illustrate relations with the differential geometry of curves and equivalence aspects.

Design/methodology/approach
The Painlevé analysis confirms the complete integrability of both Kairat-II and Kairat-X equations.

Findings
This study explores multiple soliton solutions for the two examined models. Moreover, the author showed that only Kairat-X give lump solutions and breather wave solutions.

Research limitations/implications
The Hirota’s bilinear algorithm is used to furnish a variety of solitonic solutions with useful physical structures.

Practical implications
This study also furnishes a variety of numerous periodic solutions, kink solutions and singular solutions for Kairat-II equation. In addition, lump solutions and breather wave solutions were achieved from Kairat-X model.

Social implications
The work formally furnishes algorithms for studying newly constructed systems that examine plasma physics, optical communications, oceans and seas and the differential geometry of curves, among others.

Originality/value
This paper presents an original work that presents two newly developed Painlev\'{e} integrable models with insightful findings.
Multichannel service, trust, commitment and engagement: a study in a credit union
Authors: Gomes Lucimara , Schmidt Serje , Eberle Luciene 
Published: April 2024

PurposeIn banking services, how customers interact with their bank – whether it’s through the physical branch or online – plays a significant role in how they feel about the experience. It’s not just about performing the service; it’s also about building trust, keeping them committed and getting them engaged so that a long-lasting relationship is developed. While there’s abundant research about trust and commitment in banking, not many studies have looked at how customers see both the online and offline sides of banking, especially in credit unions. Credit unions emphasize proximity with members, so it’s important to understand how these different ways of interacting affect how much people trust the credit union and stay committed to it and how engaged they feel as members. This study aims to explore this issue.Design/methodology/approachA quantitative survey was conducted using partial least squares structural equation modeling (PLS-SEM). The survey was answered by 195 members of one of the most traditional credit unions in Brazil.FindingsThe results suggest that both face-to-face and digital channels’ dimensions impact trust, which in turn influences commitment. Engagement is influenced by both trust and commitment, providing inputs to the value co-creation process.Originality/valueThe research presents relevant contributions to academia by deepening the understanding of the role of different service channels in value co-creation and customer engagement. It also offers significant contributions to the cooperative, which can improve the member experience in interaction channels to consequently develop lasting relationships and stimulate the engagement of its members.
Experiential effects on mass sport participants’ event satisfaction and behavioral intentions: examining sensory, affective, behavioral, intellectual and relational dimensions
Authors: Lianopoulos Yannis , Kotsi Nikoleta , Karagiorgos Thomas , Theodorakis Nicholas D. 
Published: April 2024

PurposeThe purpose of the present study was to investigate the interrelationships among the dimensions of sport event experience, event satisfaction and event behavioral intentions.Design/methodology/approachThe sample was comprised of 186 individuals who actively participated in a mass participation sport event. Partial least squares-structural equation modeling (PLS-SEM) was employed to test the relationships among the latent constructs.FindingsThe results indicated that the dimensions of sport event experience predicted 55% of the variance of event satisfaction and 63% of the variance of event behavioral intentions was predicted by sport event experience dimensions and event satisfaction. Specifically, the sensory, affective and relational dimensions of experience sought to have a statistically significant and positive association with event satisfaction, while event satisfaction and the relational dimension of experience were found to have a statistically significant and positive correlation with event behavioral intentions. In addition, event satisfaction was found to mediate the relationships between sensory, affective and relational experiences and event behavioral intentions.Originality/valueThe present study is one of the first that explores the relationships among sport event experience’s dimensions, event satisfaction and positive behavioral intentions in the context of sport event participation.
An analysis of social acceptance of energy in Iran: case study of fossil, nuclear, solar and wind energy
Authors: Sadabadi Ali Asghar , Mohamadi Etergeleh Fatemeh , Fartash Kiarash , Shahi Narges 
Published: April 2024

Purpose
The purpose of this paper is to investigate the social acceptance of renewable and non-renewable energies in Iran using the social acceptance pyramid.

Design/methodology/approach
Today, social acceptance is considered a very important phenomenon in the development, implementation and achievement of energy policy goals. Low acceptance will make it difficult to achieve energy development goals; therefore, social acceptance must be taken into account when making policy. Firstly, the model criteria, using data obtained from questionnaires, are weighted by the Shannon entropy method and, finally, four sources of fossil, nuclear, wind and solar energy were ranked by means of VIKOR, Technique for Order of Preference by Similarity to Ideal Solution (TOPSIS).

Findings
The results show that, in Iran, the social acceptance criterion and trust sub-criterion are the most important criteria for energy acceptance. The results of the ranking of options based on multiple-criteria decision-making (MCDM) techniques show that, given Iran's specific energy requirements, social acceptance of fossil energy is higher than wind, solar and nuclear, and wind, solar and nuclear energy come later in the rankings.

Originality/value
This research contributes to the literature in two ways: Firstly, social acceptance is considered a very important phenomenon in the development, implementation and achievement of energy policy goals; thus social acceptance must be taken into account when making policy. The results of the ranking of options based on MCDM techniques show that, given Iran's specific energy requirements, social acceptance of fossil energy is higher than wind, solar and nuclear, and wind, solar and nuclear energy come later in the rankings. Also, the social acceptance criterion and trust sub-criterion are the most important criteria for energy acceptance in Iran.
Unleashing potential: Islamic leadership’s influence on employee performance via Islamic organizational values, organizational culture and work motivation
Authors: Abdelwahed Nadia A. Abdelmegeed , Al Doghan Mohammed A. , Saraih Ummi Naiemah , Soomro Bahadur Ali 
Published: April 2024

Purpose
In the present era, the achievement of employee Islamic performance has become a significant challenge for organizations. The purpose of the study is to examine the effect of Islamic leadership on employee Islamic performance directly and indirectly by bridging the connections between employees’ Islamic organizational values, Islamic organizational culture, and Islamic work motivation among the employees of Egyptian banks.

Design/methodology/approach
The authors used quantitative methods in this study and based its findings on the data received from 312 respondents in response to a questionnaire.

Findings
By using SmartPLS 4, this study’s findings demonstrate that Islamic leadership has a positive and significant effect on Islamic organizational values, culture, employee Islamic performance and work motivation. While Islamic organizational values and Islamic organizational culture do not significantly impact employee Islamic performance, Islamic work motivation is a significant predictor of employee Islamic performance. On the one hand, Islamic organizational values and Islamic organizational culture do not mediate the relationship between Islamic leadership and employee Islamic performance. On the other hand, Islamic work motivation is a mediating variable that significantly develops the relationship between Islamic leadership and employee Islamic performance.

Practical implications
The study’s findings support policymakers and human resource management practitioners to develop plans and strategies which enhance the Islamic performance of organizations’ employees. In addition, this study’s findings provide insights for researchers and academicians in developing Islamic leadership within their organizations so that they operate by Islamic values and codes.

Originality/value
Finally, by offering an integrated model of Islamic leadership, Islamic organizational values, Islamic organizational culture and employee Islamic performance, this study’s findings fill the gaps in the context of bank employees in a developing country, namely, Egypt.
Ethical banking behavior among millennials and Gen-Z in Malaysia
Authors: Zahari Siti Aisyah , Shahimi Shahida , Alma'amun Suhaili , Arshad Mohd Mursyid 
Published: April 2024

Purpose
This study aims to determine the factors that influence ethical banking behavior among millennials and Gen-Z in Malaysia.

Design/methodology/approach
A stratified sample of 525 millennials and Gen-Z of Malaysian banking customers was used. Extended ethical decision-making (EDM) model was tested using partial least square-structural equation model for the analysis.

Findings
The findings indicated that the engagement of millennials and Gen-Z in ethical banking is influenced by factors such as intention, judgment and awareness, which shaped both generations’ ethical banking behavior.

Practical implications
This study could be a central reference point and assist banking institutions in understanding the preferences of millennials and Gen-Z.

Originality/value
This study extends the previous EDM model that focused solely on consumer's belief systems. Three aspects differentiate this paper and contribute to its originality, namely, the uniqueness of millennials and Gen-Z behavior, incorporating new variables along with the EDM models and study in Malaysian context.