bluuebunny/crossref_metadata_2025_split huggingface dataset:
Social strategies to access land influence crop diversity in northwestern Morocco
Authors: Demongeot Marilou , Hmimsa Younes , McKey Doyle , Aumeeruddy‐Thomas Yildiz , Renard Delphine 
Published: March 2024

Abstract

Much evidence supports the ecological and agronomic benefits of diversity, of both crops and environments, for building resilience and sustainability in agroecosystems. Farmers' knowledge about crop diversity is well‐documented, but aside from studies on how farmers exchange seeds and knowledge through networks, the interactions of social factors and the diversity of crops and cultivated environments have been mainly overlooked. One factor receiving attention is farmers' access to land, but in only one of its dimensions, the security of access. Here we address the different strategies by which farmers gain access to land. How does the plurality of modes of access to land influence crop choices, and thereby crop diversity? How does this plurality influence the range of environments available to individual farmers for cultivating crop diversity?

Analysing data from 51 interviews with farmers and 312 plots in agrosilvopastoral systems in northwestern Morocco, we described eight different modes of access. Each mode offers different opportunities and constraints concerning the kind of crops that can be grown on the plot. We found that an increase in the number of modes of access to land increases the crop diversity of farmers' holdings, regardless of the total area each farmer cultivates. Accessing additional plots contributed to both environmental heterogeneity and to crop diversity of farms.

In striving to gain access to land and to grow diverse crops, farmers are motivated by their notion of what it means to be a ‘real farmer’, that is, the relation to their identity. Farmers mobilize not only their economic power but also their social relationships to gain access to plots of land. Their choices are also based on their relationships to tree crops such as olive, which are economic and cultural keystone species, as well as markers of land ownership and control.

Multiple modes of access to land characterize many smallholder farming systems, which support a large fraction of the world's population. Recognizing diverse social practices of access to land that allow farmers to continue to mobilize multiple modes of access can increase resilience against unpredictable events and help maintain sustainable agroecosystems.

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Challenges in computational discovery of bioactive peptides in ’omics data
Authors: Coelho Luis Pedro , Santos‐Júnior Célio Dias , de la Fuente‐Nunez Cesar 
Published: March 2024

AbstractPeptides have a plethora of activities in biological systems that can potentially be exploited biotechnologically. Several peptides are used clinically, as well as in industry and agriculture. The increase in available ’omics data has recently provided a large opportunity for mining novel enzymes, biosynthetic gene clusters, and molecules. While these data primarily consist of DNA sequences, other types of data provide important complementary information. Due to their size, the approaches proven successful at discovering novel proteins of canonical size cannot be naïvely applied to the discovery of peptides. Peptides can be encoded directly in the genome as short open reading frames (smORFs), or they can be derived from larger proteins by proteolysis. Both of these peptide classes pose challenges as simple methods for their prediction result in large numbers of false positives. Similarly, functional annotation of larger proteins, traditionally based on sequence similarity to infer orthology and then transferring functions between characterized proteins and uncharacterized ones, cannot be applied for short sequences. The use of these techniques is much more limited and alternative approaches based on machine learning are used instead. Here, we review the limitations of traditional methods as well as the alternative methods that have recently been developed for discovering novel bioactive peptides with a focus on prokaryotic genomes and metagenomes.
Common dyadic coping and its congruence in couples facing breast cancer: The impact on couples' psychological distress
Authors: Liu Wenjia , Lewis Frances Marcus , Oxford Monica , Kantrowitz‐Gordon Ira 
Published: March 2024

AbstractObjectivePsychological distress is prevalent in couples facing breast cancer. Couples often deal with breast cancer as a unit instead of as individuals. Couple's dyadic coping is important for their adjustment to breast cancer; however, little is known about how couple's coping congruence influences their distress. This study examined how common dyadic coping (CDC) and coping congruence impact psychological distress in couples facing breast cancer.MethodsBaseline data were analyzed from 343 women with recently diagnosed early‐stage breast cancer and their partners who participated in a randomized clinical trial. Psychological distress was indicated by depressed mood and state anxiety. Common dyadic coping was measured by a self‐report scale. Coping congruence was assessed by the absolute difference between a woman's and her partner's CDC scores.ResultsHigher CDC scores were associated with lower psychological distress in both women and partners. In the CDC subscales, women who suffered less scored higher on open communication, sharing a positive outlook, and lower on avoidance coping. Partners who suffered less scored higher on open communication, sharing a positive outlook, spending time talking, and lower on avoidance coping. Greater congruence in CDC was associated with lower psychological distress in women and their partners. Congruence in sharing a positive outlook benefited both members of the dyad; congruence in avoidance coping significantly benefited patients; congruence in open communication significantly benefited partners.ConclusionsCDC and its congruence in specific areas have potential benefit to couple's psychological distress when facing breast cancer. Health care providers could consider enhancing couple's CDC and coping congruence to improve their adjustment.
Adoption of unoccupied aerial systems in agricultural research
Authors: Lachowiec Jennifer , Feldman Max J. , Matias Filipe Inacio , LeBauer David , Gregory Alexander 
Published: March 2024

AbstractA comprehensive survey and subject‐expert interviews conducted among agricultural researchers investigated perceived value and barriers to the adoption of unoccupied aerial systems (UASs) in agricultural research. These systems are often referred to colloquially as drones and are composed of unoccupied/uncrewed/unmanned vehicles and incorporated sensors. This study of UASs involved 154 respondents from 21 countries representing various agricultural sectors. The survey identified three key applications considered most promising for UASs in agriculture: precision agriculture, crop phenotyping/plant breeding, and crop modeling. Over 80% of respondents rated UASs for phenotyping as valuable, with 47.6% considering them very valuable. Among the participants, 41% were already using UAS technology in their research, while 49% expressed interest in future adoption. Current users highly valued UASs for phenotyping, with 63.9% considering them very valuable, compared to 39.4% of potential future users. The study also explored barriers to UAS adoption. The most commonly reported barriers were the “High cost of instruments/devices or software” (46.0%) and the “Lack of knowledge or trained personnel to analyze data” (40.9%). These barriers persisted as top concerns for both current and potential future users. Respondents expressed a desire for detailed step‐by‐step protocols for drone data processing pipelines (34.7%) and in‐person training for personnel (16.5%) as valuable resources for UAS adoption. The research sheds light on the prevailing perceptions and challenges associated with UAS usage in agricultural research, emphasizing the potential of UASs in specific applications and identifying crucial barriers to address for wider adoption in the agricultural sector.
Post‐translational modification sites are present in hydrophilic cavities of alpha‐synuclein, tau, FUS, and TDP‐43 fibrils: A molecular dynamics study
Authors: Kochen Noah Nathan , Seaney Darren , Vasandani Vivek , Murray Marguerite , Braun Anthony R. , Sachs Jonathan N. 
Published: March 2024

AbstractHydration plays a crucial role in the refolding of intrinsically disordered proteins into amyloid fibrils; however, the specific interactions between water and protein that may contribute to this process are still unknown. In our previous studies of alpha‐synuclein (aSyn), we have shown that waters confined in fibril cavities are stabilizing features of this pathological fold; and that amino acids that hydrogen bond with these confined waters modulate primary and seeded aggregation. Here, we extend our aSyn molecular dynamics (MD) simulations with three new polymorphs and correlate MD trajectory information with known post‐translational modifications (PTMs) and experimental data. We show that cavity residues are more evolutionarily conserved than non‐cavity residues and are enriched with PTM sites. As expected, the confinement within hydrophilic cavities results in more stably hydrated amino acids. Interestingly, cavity PTM sites display the longest protein‐water hydrogen bond lifetimes, three‐fold greater than non‐PTM cavity sites. Utilizing the deep mutational screen dataset by Newberry et al. and the Thioflavin T aggregation review by Pancoe et al. parsed using a fibril cavity/non‐cavity definition, we show that hydrophobic changes to amino acids in cavities have a larger effect on fitness and aggregation rate than residues outside cavities, supporting our hypothesis that these sites are involved in the inhibition of aSyn toxic fibrillization. Finally, we expand our study to include analysis of fibril structures of tau, FUS, TDP‐43, prion, and hnRNPA1; all of which contained hydrated cavities, with tau, FUS, and TDP‐43 recapitulating our PTM results in aSyn fibril cavities.
A novel mutation in IAA16 is associated with dicamba resistance in Chenopodium album
Authors: Ghanizadeh Hossein , He Lulu , Griffiths Andrew G. , Harrington Kerry C. , Carbone Vincenzo , Wu Haotian , Tian Ke , Bo Han , Xinhui Duan 
Published: March 2024

AbstractBACKGROUNDResistance to dicamba in Chenopodium album was first documented over a decade ago, however, the molecular basis of dicamba resistance in this species has not been elucidated. In this research, the resistance mechanism in a dicamba‐resistant C. album phenotype was investigated using a transcriptomics (RNA‐sequence) approach.RESULTSThe dose–response assay showed that the resistant (R) phenotype was nearly 25‐fold more resistant to dicamba than a susceptible (S) phenotype of C. album. Also, dicamba treatment significantly induced transcription of the known auxin‐responsive genes, Gretchen Hagen 3 (GH3), small auxin‐up RNAs (SAURs), and 1‐aminocyclopropane‐1‐carboxylate synthase (ACS) genes in the susceptible phenotype. Comparing the transcripts of auxin TIR/AFB receptors and auxin/indole‐3‐acetic acid (AUX/IAA) proteins identified from C. album transcriptomic analysis revealed that the R phenotype contained a novel mutation at the first codon of the GWPPV degron motif of IAA16, resulting in an amino acid substitution of glycine (G) with aspartic acid (D). Sequencing the IAA16 gene in other R and S individuals further confirmed that all the R individuals contained the mutation.CONCLUSIONIn this research, we describe the dicamba resistance mechanism in the only case of dicamba‐resistant C. album reported to date. Prior work has shown that the dicamba resistance allele confers significant growth defects to the R phenotype investigated here, suggesting that dicamba‐resistant C. album carrying this novel mutation in the IAA16 gene may not persist at high frequencies upon removal of dicamba application. © 2024 The Authors. Pest Management Science published by John Wiley & Sons Ltd on behalf of Society of Chemical Industry.
Robust adaptive Kalman filter for structural performance assessment
Authors: Yi Shenglun , Su Tingli , Tang ZhenYun 
Published: March 2024

SummaryStructural performance assessment is a critical stage in the health monitoring for the maintenance and risk management of engineering structures, in which the interstory drift is a key indicator. In this paper, a robust adaptive Kalman filter is proposed for an interstory drift estimation problem to show the health condition of steel structures in the case that the statistics or internal dynamics describing the signals and measurements are not known precisely. More precisely, we build an adaptive current Jerk model (ACJM) where the model parameters are updated in each time step to presuppose the statistics characterization of the steel dynamic, while the unknown measurement noise covariance is adapted based on a fixed‐lag innovation with respect to measurements. Moreover, a robust adaptive Kalman filter is designed for the modelling uncertainties in each time increment by solving a minimax game: one player tries to select an “actual” model far from the proposed ACJM with an exponential decay tolerance, while its “hostile” player, namely, the optimum filter, is designed by minimizing the estimation error according to the selected “actual” model. Finally, some simulation and experimental results show the effectiveness of the proposed algorithm.
A One‐Pot Synthesized Chemodosimetric Chemosensor for Highly Sensitive Cyanide Ion Detection in Aqueous Media and from Tobacco Smoke
Authors: Umabharathi P. S. , Purushothaman P. , Karpagam S. , Dasgupta Tiashaa , Tamizhselvi Ramaswamy 
Published: March 2024

AbstractA sustainable future world consistently attributes to the development of eco‐friendly methods and materials for detection and elimination of toxic substances from the environment. While addressing the issues, pyrazole carbonitrile derived Schiff base PYR−TZ has been designed and employed for colorimetric and turn on fluorometric cyanide ion sensing. PYR−TZ demonstrated high cyanide ion (CN−) sensitivity with a 1 : 1 binding stoichiometry in aqueous solution. By preventing intramolecular charge transfer, the PYR−TZ sensor demonstrated excellent selectivity towards CN, which caused a color transition from colorless to yellow and impressive “turn‐on” fluorescence emission. The detection thresholds for CN− are 6.5 nm for absorbance spectra and 0.396 nm emission spectra, respectively. Under typical ecological and physiological settings (pH 1–12), the PYR−TZ sensor can function as an effective chemical sensor for detecting the CN− ions. Additionally, the sensor can find CN in tobacco commercial products like cigarettes and cigars. PYR−TZ is a great cyanide sensor probe that has a number of benefits, which includes simple synthesis, distinct color and emission change, a high degree of selectivity, lesser limit of detection, reversibility, and good anti‐interference ability to analyze solution and tobacco commercial things, together with fluorescence imaging. The theoretical optimized structure and electronic transitions were confirmed by DFT and TDDFT studies. On the basis of theoretical and experimental calculations (DFT), the mechanism of the metal ion complex is postulated.
Cathode Material Designing and Characterization: Co3O4/N‐doped Porous Carbon for Asymmetric Supercapacitors
Authors: Mulik Swapnajit V. , Pandhare Amol B. , Soni Saurabh S. , Dhas Suprimkumar D. , Delekar Sagar D. 
Published: March 2024

AbstractMesoporous Co3O4/N‐PC in powder form was synthesized via a wet‐chemical approach, and the resulting material was deposited onto nickel foam as a substrate without the use of a binder. Prior to device fabrication, a thorough analysis of suitable and cost‐effective aqueous alkaline and neutral electrolytes was conducted. Electrolyte optimization was performed using Co3O4/N‐PC/NF electrode with Na2SO4, NaOH, LiOH, and KOH electrolytes. The supercapacitor performance of the binder‐free deposited materials was found to be superior in KOH electrolyte compared to other aqueous electrolytes at equal concentrations. Further optimization of the KOH electrolyte concentration was carried out to achieve the best electrochemical performance for the Co3O4/N‐PC/NF electrode. Electrochemical results demonstrated that the Co3O4/N‐PC/NF electrode performed well in 1 M KOH electrolyte, surpassing its performance at other concentrations. Subsequently, a solid‐state asymmetric device was fabricated, utilizing Co3O4/N‐PC, activated carbon, and a KOH+PVA gel as the cathode, anode, and electrolyte, respectively. The assembled asymmetric Co3O4/N‐PC/NF‐AC/NF device exhibited an energy density of 12.08 Wh kg−1 and a power density of 2500 W kg−1 within a potential window of 1.5 V. Impressively, after nearly 3000 continuous GCD cycles, the device showed negligible initial specific capacitance decay. The device was also successfully tested for powering the LED.
Dioxirane‐Based Stereoselective and Oxidative Transformations
Authors: Neogi Ishita , Parida Keshaba N. 
Published: March 2024

AbstractThe synthesis of chiral organic molecules is a purity‐driven research that has become an essential part of our lives due to their applications in pharmaceuticals. Contemporary research focuses on the exploration of synthetic protocols that obviate the use/generation of hazardous chemicals. In this regard, dioxiranes are readily accessed as a reagent solution or catalyst (in situ) from the reaction of ketone with a co‐oxidant like Oxone® or H2O2; the latter makes the protocol very green and inexpensive. It has shown the potential to replace transition metal‐based oxygenation protocols. The dioxirane‐mediated asymmetric reactions include oxidations, epoxidations, C−H hydroxylations, etc. Both stoichiometric and catalytic protocols of dioxiranes are been explored for the oxyfunctionalization of chiral natural product derivatives such as Penicillin, nucleosides, amino acids, carbohydrates, etc. In addition, these are employed as key oxygenation agents during the synthesis of natural products like (+)‐Plagiogyrin A, Portimine, Taxol, Bryostatin, dafachronic acid, majucinoids, eldecalcitol, Spirochensilide A, etc. The review consolidates the development of both achiral and chiral dioxiranes in application to asymmetric synthesis and oxygenation of chiral molecules.
Structure–Properties Correlations in the Range of Cationic Spiropyrans as Analogues of Cyanine Dyes
Authors: Kozlenko Anastasiia S. , Pugachev Artem D. , Ozhogin Ilya V. , Rostovtseva Irina A. , Makarova Nadezhda I. , Tkachev Valery V. , Utenyshev Andrei N. , Demidov Oleg P. , Borodkin Gennady S. , Aldoshin Sergey M. , Metelitsa Anatoly V. 
Published: March 2024

AbstractRecently the need for smart materials has been extremely growing, and the development of materials with appropriate characteristics has become one of the main challenges. Heptamethine cyanine dyes are widely used in theranostics and photovoltaics due to their remarkable optical properties. However, they are characterized by “rigid” non–changable properties. The main aim of the current study is to unveil correlation between structure and optical properties in the range of vinyl‐3H‐indolium substituted spiropyrans, which can be considered as the closest analogs of heptamethine cyanines with the photocontrolable optical and fluorescent properties. The effects of substitution in indoline and 2H‐chromene cycles, as well as anion change are under the study. To achieve this goal, a series of spiropyran iodides and perchlorates with methyl, methoxy substituents or fluorine atom in position 6′, as well as a conjugated vinyl‐3H‐indolium fragment in position 8′, were synthesized. The structure of the compounds was carefully studied using SC XRD, NMR, IR and mass spectroscopy. Then, studies on absorption and photoluminescence characteristics, as well as photochromic behavior were carried out.
Design, Synthesis, Cytotoxic Evaluation, and Molecular Docking of New Alkyl Triphenylphosphonium Curcumin Derivatives
Authors: Hoang Dang Phu , Hoai Tran Tu , Huu Le Tho , Thi Nguyen Thu‐Ha , Binh Vong Long , Thanh Thi Nguyen Mai , Trung Nguyen Nhan 
Published: March 2024

AbstractDespite the previous anticancer effects of curcumin against various cancer cell lines, in vitro, pre–clinical, and clinical studies have faced constraints, particularly at high doses. Therefore, the mitochondria–targeted approach represents a promising trend in cancer drug development. This study successfully synthesized three new alkyl triphenylphosphonium ester curcumin derivatives (1–3) with good yield. They demonstrated cytotoxicity against MCF‐7 cells with IC50 values of 49.72, 62.57, and 91.73 μM, respectively. These values indicated higher potency than free curcumin (IC50>100 μM). Molecular docking studies of curcumin and three derivatives 1–3 with two estrogen receptor α (ERα) ligand binding domains, 3ERT (antagonist recognition and antiproliferative function), and 1GWR (agonist recognition and pro–proliferative function), were carried out. These domains are important targets in hormone–dependent anticancer strategies. The favourable docking scores and key residue interactions suggested that these derivatives could be the potential antagonists. Three synthesized alkyl–TPP+ curcumin ester derivatives (1–3) demonstrated more potent cytotoxic efficacy than curcumin, particularly against the human MCF‐7 breast cancer cell line. In addition, molecular docking studies suggested their potential as antagonists of ERα. The in silico ADMET data of three derivatives (1–3) showed compliance with the Lipinski rule and demonstrated their absorption, distribution, metabolism, and excretion properties.
Examining the trajectory of meaning violation and its bidirectional relationship with perceived posttraumatic growth
Authors: Yang Tongping , Bi Chongzeng 
Published: March 2024

AbstractDespite extensive theoretical discussions on the dynamic process of meaning violation (MV) and restoration, empirical research on this topic remained lacking. This study aimed to explore the trajectory of MV and the bi‐directionality between MV and perceived posttraumatic growth (PPTG). This study employed a 3‐wave longitudinal design spanning over 3 months, and a sample of participants from China who experienced any distressing event within the past 3 months was considered eligible. Participants (N = 215; aged 18–38 years old) were instructed to assess MV and PPTG regarding a chosen event. A latent growth model was used to examine changes in MV over time and a random intercept cross‐lagged panel model was used to analyze bidirectional associations between MV and PPTG. Results revealed that, at the within‐person level, MV at T1 negatively predicted PPTG at T2, while PPTG at T2 negatively predicted MV at T3. These results indicate that the sense of MV may have impeded PPTG in the initial stages, whereas PPTG might serve as a predictor for diminished MV at later stages. At the between‐person level, a positive relationship between these two constructs was observed, suggesting that individuals who experienced higher levels of MV, in general, also tended to report greater PPTG. These findings reflect the complex and dynamic nature of meaning reconstruction processes and provide empirical evidence for the meaning‐making model.