bluuebunny/crossref_metadata_2025_split huggingface dataset:
Salivary cortisol secretion in remitted bipolar patients and offspring of bipolar parents
Authors: Deshauer Dorian , Duffy Anne , Meaney Michael , Sharma Shakti , Grof Paul 
Published: July 2006

Objectives:  It is generally believed that cortisol secretion normalizes during clinical remission in mood disorders. However, this assumption has been challenged by preliminary reports of enhanced cortisol secretion in remitted bipolar patients and in the offspring of bipolar parents. The purpose of this study is to replicate findings of increased cortisol secretion during clinical remission in bipolar patients and in the offspring of bipolar parents, rigorously controlling for known confounders.Methods:  We conducted intensive cortisol sampling (six samples per day for three test days, on three consecutive weekends) on 15 bipolar type I and type II patients and 28 unrelated offspring of bipolar parents. Offspring had a history of unipolar depression. Participation was restricted to cases in complete sustained remission. Controls were matched as closely as possible for age, sex, and education. Mood and sleep measures were recorded on each sampling day.Results:  In total, 743 samples were collected from the patient group and 576 from controls. Correcting for repeat measures, there was no statistically significant difference in cortisol secretion at any sampling time between remitted bipolar patients, remitted offspring of bipolar parents, and normal controls. The cortisol waking response did not differ between patients and controls. Covariates, including sex, age, Beck depression score and hours of sleep, were not statistically significant.Conclusions:  Our observations are consistent with the view that complete sustained clinical remission is associated with normal salivary cortisol levels throughout the day. A personal or family history of bipolar disorder per se does not appear to confer added risk for increased salivary cortisol secretion during sustained clinical remission.
Attention‐deficit hyperactivity disorder – bipolar comorbidity in children and adolescents
Authors: Masi Gabriele , Perugi Giulio , Toni Cristina , Millepiedi Stefania , Mucci Maria , Bertini Nicoletta , Pfanner Chiara 
Published: July 2006

Objective:  A substantial portion of juvenile bipolar disorder (BD) has a comorbid attention‐deficit hyperactivity disorder (ADHD). The aim of our study was to analyze the cross‐sectional and longitudinal implications of such comorbidity in children and adolescents with BD.Methods:  Ninety‐eight refereed patients (mean age 13.7 ± 3.0 years) with a diagnosis of BD by the Schedule for Affective Disorders and Schizophrenia for School‐Age Children, Present and Lifetime version (K‐SADS‐PL) were followed for 6 months.Results:  Thirty‐seven BD patients (37.8%) presented a lifetime diagnosis of comorbid ADHD. The mean age of onset of ADHD was 3.7 ± 1.1 years, and the mean age of onset of BD was 10.0 ± 3.2 years. Bipolar subjects with comorbid ADHD were predominantly male, younger, and had an earlier onset of BD (8.1 ±  2.8 versus 11.1 ± 2.9 years). Bipolar‐ADHD patients presented more frequently a chronic rather than an episodic course of BD, with an irritable rather than an elated mood. They showed higher rates of oppositional defiant disorder/conduct disorder, lower rates of panic disorder, and less frequently received antidepressant medications. Finally, ADHD comorbidity was associated with a greater psychosocial impairment.Conclusions:  ADHD comorbidity is frequent in juvenile BD and can influence age of onset, phenomenology, comorbidity, and course of BD. A timely diagnosis should improve our efforts regarding the outcome of these subjects.
Brief report on the United States Food and Drug Administration Blood Products Advisory Committee recommendations for management of donors and units testing positive for hepatitis B virus DNA
Authors: Lucey C. 
Published: July 2006

Background and Objectives  This article briefly recounts the 21st July 2005, Blood Products Advisory Committee (BPAC) meeting concerning recommendations for management of donors and units testing positive for hepatitis B virus (HBV) DNA.Materials and Methods  The author attended the meeting. The United States Food and Drug Administration (FDA) web site was used for meeting materials, and handouts were collected at the meeting to provide narrative information. Two European experts assisted with HBV subject matter.Results  The proceedings of the advisory committee, the issue briefing materials, and testing algorithms are presented.Conclusion  BPAC voted concurrence with the FDA algorithm for Management of Donors and Units Testing Positive for Hepatitis B Virus DNA.
Yield and Forage Quality of Different ×Festulolium Cultivars in Winter
Authors: Opitz v. Boberfeld W. , Banzhaf K. 
Published: July 2006

Abstract×Festulolium ssp. are of particular interest as autumn‐saved herbage in the winter grazing system, but information concerning their performance in this low‐input system is not available. To this end, we examined dry matter (DM) yield and forage quality in winter of four different cultivars of ×Festulolium ssp. (×Festulolium pabulare, Festulolium braunii), either with festucoid or loloid attributes, compared with Festuca arundinacea Schreb. Furthermore, pre‐utilization (accumulation since June or July) and date of winter harvest (December or January) were varied examining the influence of different sward management. DM yield, crude protein, metabolizable energy (ME) (in vitro rumen fermentation technique), acid detergent fibre (ADF) and ergosterol concentration were determined. Within all years, the festucoid cultivars (mean 3.4 t ha−1) attained significant higher yields during winter than the loloid cultivars (mean 1.6 t ha−1), but their yields were comparable with F. arundinacea (mean 3.0 t ha−1). Crude protein was decisively influenced by the different yield levels of the cultivars resulting in higher values for the loloid cultivars. Energy concentrations decreased with later winter harvest, whereas ADF as well as ergosterol concentrations frequently increased from December to January. The greatest differences between festucoid and loloid cultivars were generally observed during severe winters. Obviously, the festucoid cultivars were better adapted to a utilization as autumn‐saved herbage than the cultivars with rather loloid attributes. However, the hybrids did not surpass F. arundinacea regarding yield and quality.
Yield, Boll Distribution and Fibre Quality of Hybrid Cotton (Gossypium hirsutum L.) as influenced by Organic and Modern Methods of Cultivation
Authors: Blaise D. 
Published: July 2006

AbstractIndia is the largest cotton‐growing country (8.9 million hectares) in the world and most of the area is rain‐dependent. Large amount of pesticides are used for the control of sucking pests and lepidopterans. Increasing demand for clean organic fibre has led to an interest in organic cotton. However, information on the effects of organic cultivation on fibre quality is limited. Seed cotton yield and fibre quality (length, strength, micronaire and uniformity) were determined for an organic and modern method of cultivation during 3 years (2002–2003 to 2004–2005) of a 11‐year (1994–1995 to 2004–2005) study. Vertical and horizontal distribution of bolls on a cotton plant was also determined in 2003–2004 and 2004–2005. At the end of year 11, soil samples were collected and analysed for soil organic carbon content, water‐stable aggregates (%), and mean weight diameter. Averaged over 3 years, an additional 94 kg seed cotton ha−1 was produced in the organic over the modern method of cultivation and the difference was significant. The year × treatment interaction was significant. Seed cotton yield in the organic plots was significantly greater than the modern method of cultivation plots in 2003–2004 because of a well‐distributed normal rainfall and low pest incidence. The main stem nodes 13–22 accounted for the largest numbers of bolls present on the plant. Plants of the organic plots had significantly (37–71 %) more bolls on nodes 13–27 than those for the plants of the modern method of cultivation. Lateral distribution of bolls on a sympodial (fruiting) branch, was noticed up to fruiting point 11. However, treatment differences were not significant. With regard to fibre quality (length, strength, fineness and uniformity), differences between years were significant. Inferior quality fibre was produced in 2004–2005 because of delayed planting and early cessation of rain. On average, cotton grown under organic conditions compared with the modern method of cultivation had significantly better fibre length (25.1 vs. 24.0 mm) and strength (18.8 vs. 17.9 g tex−1). Soil samples of the organic plots had significantly greater C content, water‐stable aggregates and mean weight diameter than the modern method of cultivation plots. Differences were restricted to the top layers (0–0.1 and 0.1–0.2 m). Yield benefits of growing cotton in an organic system over the modern method of cultivation are expected to be greater in years receiving normal rainfall and having low pest incidence.
High‐resolution mapping of the nud locus controlling the naked caryopsis in barley
Authors: Taketa S. , Awayama T. , Amano S. , Sakurai Y. , Ichii M. 
Published: July 2006

AbstractThe hulled or naked caryopsis character of barley is an important agronomic trait because of the direct link to its use. A single recessive gene, nud, located on the long arm of chromosome 7H, controls the naked caryopsis character. Previously, linked amplified fragment length polymorphism (AFLP) bands from bulked segregant analysis were screened, and the nud gene was mapped in a population of 151 F2 plants. In the present study, the aim was to construct a high‐resolution map of the nud gene towards its positional cloning. Two AFLP bands were converted into sequence‐characterized amplified region (SCAR) markers (sKT5 and sKT9), and a previously reported SCAR marker sKT3 was improved for more reliable detection of polymorphism. A total of 2380 segregants derived from five cross‐combinations were analysed, and the nud gene was flanked by sKT3 and sKT9, at the 0.6‐cM proximal and the 0.06‐cM distal side, respectively. The SCAR markers developed in this study should be useful for marker‐assisted selection in naked barley breeding employing crosses between naked and hulled accessions.
Prospects for hybrid breeding in winter triticale: II. Relationship between parental genetic distance and specific combining ability
Authors: Tams S. H. , Bauer E. , Oettler G. , Melchinger A. E. , Schön C.‐C. 
Published: July 2006

AbstractSignificant relative midparent heterosis (MPH%) for grain yield in triticale (×Triticosecale Wittm.) has generated interest in the development of hybrid cultivars. The objectives of this study were to (i) examine the association between parental genetic distance (GD) and specific combining ability (SCA), (ii) investigate the existence of genetically distant heterotic groups in elite germplasm, and (iii) draw conclusions for future hybrid breeding in winter triticale. Genetic distance between 61 lines was estimated, based on 93 polymorphic simple sequence repeat (SSR) marker loci and 10 AFLP (amplified fragment length polymorphism) primer‐enzyme combinations (PEC). Agronomic data of 206 F1 crosses and their 61 parental lines grown in six German environments were published recently in a companion study. Correlations were made between SCA for grain yield, number of spikes/m2, 1000‐kernel weight and number of kernels per spike with GD estimates of the 56 female and five male parents (testers). Principal co‐ordinate analyses (PCoA) based on SSR data revealed no distinct subgroups in the germplasm. Correlations between GD and SCA were low for all traits (|r| ≤ 0.31), which hampers the prediction of SCA from molecular data. A multi‐stage procedure is recommended for future hybrid breeding in triticale by applying a pragmatic approach for the grouping of germplasm following the early history of hybrid breeding of maize.
QTL analysis of resistance to Fusarium head blight in wheat using a ‘Frontana’‐derived population
Authors: Mardi M. , Pazouki L. , Delavar H. , Kazemi M. B. , Ghareyazie B. , Steiner B. , Nolz R. , Lemmens M. , Buerstmayr H. 
Published: July 2006

AbstractFusarium head blight (FHB or head scab) has become a major limiting factor for sustainable wheat (Triticum aestivum L.) production around the world. For quantitative trait loci (QTL) analysis of resistance to FHB, F3 plants and F3 : 5 lines, derived from a ‘Frontana’ (moderately resistant)/‘Seri82’ (susceptible) cross, were spray‐inoculated in 2001 and 2002, respectively. Artificial inoculations were carried out under field conditions. Of 273 SSR and AFLP markers, 250 could be mapped and they yielded 42 linkage groups, covering a genetic distance of 1931 cM. QTL analysis was based on the constructed linkage map and area under the disease progress curve (AUDPC). The analyses revealed three consistent QTLs associated with FHB resistance on chromosomes 1BL, 3AL and 7AS explaining 7.9%, 7.7% and 7.6% of the phenotypic variation, respectively, above 2 years. The results confirmed the previously described resistance QTL of ‘Frontana’ on chromosome 3AL. A combination of ‘Frontana’ resistance with ‘Sumai‐3’ resistance may lead to lines with augmented resistance expression.
Seed colour, seed weight and seed oil content in Linum usitatissimum accessions held by Plant Gene Resources of Canada
Authors: Diederichsen A. , Raney J. P. 
Published: July 2006

AbstractThe purpose of this study was to investigate variation of and relationships among seed colour, seed weight and seed oil content in cultivated flax (Linum usitatissimum L. ssp. usitatissimum). Seed from 2934 flax genebank accessions recently grown at Saskatoon, SK, Canada, originating from 72 countries was used to describe the variation of the seed characters. The dominant seed colour of the accessions was medium brown (2730 accessions, 93.0%), followed by yellow (126 accessions, 4.3%). Based on single observations for all accessions, the overall mean and standard deviation was 5.95 ± 1.22 mg/seed for seed weight and 38.3 ± 1.74% for oil concentration. Within three infraspecific groups of flax, seed weight, oil concentration and oil amount per seed increased in the following order: fibre flax (convar. elongatum), intermediate flax (convar. usitatissimum), large‐seeded flax (convar. mediterraneum). The world collection exceeded the range of variation of seed weight and oil concentration found in 52 North American cultivars. There was a weak, positive association of higher oil concentration with higher seed weight (r2 = 0.32; P < 0.001). Yellow‐seeded flax had a higher seed weight (6.31 vs. 5.92 mg/seed) and oil concentration (39.4% vs. 38.3%) than brown‐seeded flax. There was a tendency for yellow seed colour to be associated with higher oil concentration in all seed weight classes. The results suggested that indirect selection for increased seed oil concentration in flax is possible by selection for higher seed weight and yellow seed colour.
Genotypic and temperature effects on wheat grain yield and quality in a hot irrigated environment
Authors: Tahir I. S. A. , Nakata N. , Ali A. M. , Mustafa H. M. , Saad A. S. I. , Takata K. , Ishikawa N. , Abdalla O. S. 
Published: July 2006

AbstractHigh temperature influences both grain yield and end‐use quality of wheat. The objectives of this study were to evaluate the performance of selected wheat genotypes under heat stress and to examine the effects of high temperatures during grain filling on grain yield and end‐use quality parameters. Fifteen bread wheat genotypes in 2000/2001 and 18 genotypes in 2002/2003 were evaluated under the optimum and late‐sowing conditions of the irrigated hot environment of the Gezira Research Farm, Wad Medani, Sudan. The genotypes comprised released varieties and elite lines from the Sudanese wheat improvement programme. Data collected included grain yield, grain weight and grain end‐use quality including protein content, protein composition, SDS sedimentation values (SDSS) and gluten strength as determined by mixograph analyses. High temperatures significantly decreased grain yield by decreasing grain weight. Although genotypes exhibited variation in magnitude of response, results indicated that high temperature during grain filling increased both soluble and insoluble protein contents, SDSS, mixograph peak height (MPH) and the descending slope at 2 min past peak (MDS). In contrast, mixograph peak time (MPT) and the curve width at 2 min past peak (MCW) were significantly decreased. Flour protein correlated positively with SDSS, MPH and MDS and negatively with MCW. MPT correlated negatively with MDS and positively with MCW. Results indicate that high temperature increased both soluble and insoluble protein contents, SDSS and MPH, and hence the gluten strength, but decreased flour mixing time and tolerance and hence the dough elasticity. Variation observed among genotypes suggests that grain end‐use quality could be improved under high temperature conditions utilizing the available variability; however, it might require evaluation under various growing conditions.
Transgressive segregation for reduced glucosinolate content in Brassica carinata A. Braun
Authors: Márquez‐Lema A. , Fernández‐Martínez J. M. , Pérez‐Vich B. , Velasco L. 
Published: July 2006

AbstractSuccessful commercial utilization of the meal by‐product of Brassica oilseed crops requires the cultivation of cultivars with low glucosinolate (GSL) content in the seeds; however, such cultivars are not yet available in Brassica carinata. The objective of the present research was to search for transgressive segregants with further‐reduced GSL content in the progeny of crosses involving four B. carinata lines with reduced GSL content (90 compared with 120 μmol/g seed in standard germplasm). The four lines were crossed following a diallel design and F2 phenotypes (F3 seed bulked) were analysed for GSL content. F2 phenotypes with a transgressive GSL content lower than the parents were identified in all crosses involving the line S2–1241, suggesting that this line carries alleles for reduced GSL content not present in the other lines. F3 : 4 lines from transgressive F2 phenotypes were evaluated for 2 years, which resulted in the selection of an F3 : 4 line with an average GSL content of 58 and 46 μmol/g seed, respectively compared with 84 and 62 μmol/g seed, respectively in S2–1241.
Seed storage protein composition of Hellenic bread wheat cultivars
Authors: Xynias I. N. , Kozub N. O. , Sozinov I. A. 
Published: July 2006

AbstractThe allelic diversity in seed storage proteins of 25 bread wheat cultivars grown in Hellas was investigated. In total, 15–20 seeds per cultivar were used for the determination of the alleles present at the loci coding for high‐molecular‐weight glutenin subunits and gliadins. For this purpose, acid polyacrylamide gel electrophoresis for gliadins and SDS‐electrophoresis for glutenins were employed. Analysis of the electrophoretic patterns revealed that intravarietal selections obtained from the cultivar ‘Nestos’, together with the cultivar ‘Eurydice’ which was selected from the cultivar ‘Nestos’, were identical to their original cultivar and to the cultivar ‘Dodoni’. The cultivars ‘Penios’, ‘Siette Cerros E’, ‘Gorgona’ and ‘Louros’, although recorded to differ in descent, were found to be identical at all the loci examined. Finally, it was revealed that four of the Hellenic cultivars carry the wheat‐rye 1BL/1RS translocation. These data could be beneficial for a better understanding of the existing differences in quality and stress‐resistance between the cultivars examined.
Two chromosome segments confer multiple potyvirus resistance in maize
Authors: Lübberstedt T. , Ingvardsen C. , Melchinger A. E. , Xing Y. , Salomon R. , Redinbaugh M. G. 
Published: July 2006

AbstractPotyviruses cause serious yield losses in maize production worldwide. While the maize dwarf mosaic virus (MDMV) predominates in the USA, sugarcane mosaic virus (SCMV) is a major pathogen in China and Germany. In previous studies, inbred FAP1360A revealed complete resistance against both MDMV and SCMV. Two major SCMV resistance genes, Scmv1 and Scmv2, were located on chromosomes 6 and 3, respectively, in populations derived from crosses with the susceptible inbred line F7. For validation of these results obtained in segregating backcross‐ or F2:3‐populations, near‐isogenic lines to F7 have been produced after one initial cross to FAP1360A by repeated backcrossing to F7, phenotypic selection for SCMV resistance, and marker‐assisted selection for the Scmv1 and Scmv2 regions from FAP1360A. The near‐isogenic line F7R has been studied in detail both at the genomic level and for resistance to different potyviruses. Based on 112 polymorphic simple sequence repeat markers, F7R received genomic segments introgressed from FAP1360A exclusively in the Scmv1 and Scmv2 chromosomal regions. F7R conferred complete resistance to SCMV and MDMV, but also to zea mosaic virus and to systemic infection by wheat streak mosaic virus. FAP1360A, F7, F7R were not systemically infected by high plains virus. Thus, introgression of Scmv1 and Scmv2 from FAP1360A into F7 was sufficient to generate the first potyvirus multiresistant European Flint line reported so far.
Identification of resistance gene analogs as markers of disease resistance loci in oats, using near‐isogenic lines
Authors: Irigoyen M. L. , Loarce Y. , Friero E. , Fominaya A. , Ferrer E. 
Published: July 2006

AbstractGenomic sequences with features of the major class of disease resistance genes and which bear nucleotide‐binding leucine‐rich repeat sequences (resistance gene analogs; RGA) were tested as potential markers of crown rust resistance loci in hexaploid oats. Two collections of paired near‐isogenic lines carrying resistance to different isolates of crown rust, Puccinia coronata were screened. Two out of the four RGAs assayed showed restriction fragment length polymorphism (RFLP) between one line of each collection and its recurrent parent. The paired lines X466 and D494 were polymorphic for RGA III2.2 and the pair of lines X470 and D504 were polymorphic for RGA III2.18. The III2.18 polymorphism was located in the hexaploid map Avena byzantina cv. ‘Kanota’ × A. sativa cv. ‘Ogle’ in linkage group KO17 in a region previously associated with crown rust resistance. In addition, 220 random primers were used for random amplified polymorphic DNA (RAPD) analysis to screen the two sets of NILs. Only one polymorphic band was obtained that differentiated the paired lines X470 and D504 from their parents. The RAPD band was used as a probe and the relevant RFLP that differentiated the NILs X470 and D504 was found at 1.7 cM from the III2.18 marker in KO17. RFLP analysis using probes previously mapped in KO17 confirmed differences for X470 and D504 in the region around the III2.18 marker. These results suggest that the resistance locus shared by this pair of NILs is probably linked to the markers revealed by RGA III2.18. The use of RGAs as RFLP probes in the screening of NILs with differences in crown rust resistance has proved to be more effective than RAPDs for finding polymorphic markers possibly linked to resistance loci.