bluuebunny/crossref_metadata_2025_split huggingface dataset:
Current data processing methods and reporting standards for untargeted analysis of volatile organic compounds using direct mass spectrometry: a systematic review
Authors: Rosenthal K , Lindley MR , Turner MA , Ratcliffe E , Hunsicker E 
Published: March 2024

Abstract
Introduction
Untargeted direct mass spectrometric analysis of volatile organic compounds has many potential applications across fields such as healthcare and food safety. However, robust data processing protocols must be employed to ensure that research is replicable and practical applications can be realised. User-friendly data processing and statistical tools are becoming increasingly available; however, the use of these tools have neither been analysed, nor are they necessarily suited for every data type.

Objectives
This review aims to analyse data processing and analytic workflows currently in use and examine whether methodological reporting is sufficient to enable replication.

Methods
Studies identified from Web of Science and Scopus databases were systematically examined against the inclusion criteria. The experimental, data processing, and data analysis workflows were reviewed for the relevant studies.

Results
From 459 studies identified from the databases, a total of 110 met the inclusion criteria. Very few papers provided enough detail to allow all aspects of the methodology to be replicated accurately, with only three meeting previous guidelines for reporting experimental methods. A wide range of data processing methods were used, with only eight papers (7.3%) employing a largely similar workflow where direct comparability was achievable.

Conclusions
Standardised workflows and reporting systems need to be developed to ensure research in this area is replicable, comparable, and held to a high standard. Thus, allowing the wide-ranging potential applications to be realised.
The effect of writing script on efficiency and metacognitive monitoring in inferential word learning
Authors: Polyanskaya Leona , El-Dakhs Dina Abdel Salam , Tao Ming , Chu Fengfeng , Ordin Mikhail 
Published: March 2024

AbstractThe writing system – the transparency of orthography in alphabet-based systems and differences between logographic and phonetic-based systems – can affect the efficiency of inferential word learning when words are introduced visually. It can also shape how people self-evaluate their learning success (we refer to such type of self-evaluation as metacognitive monitoring of word learning). By contrast, differences in metacognition and learning performance do not emerge when words are presented auditorily. To measure metacognition, we assessed retrospective confidence by asking participants to rate their certainty about the correctness of their responses. As this direct question raises a person’s conscious awareness of how well they have learned a particular lexical unit, it allowed us to measure those aspects of metacognition that are modulated by consciousness. Such consciousness comes into play when a word is associated with an object. Differences in conscious awareness of the word learning success when words are represented visually make differential demands on word learning across languages and modalities. The observed differences between populations using different writing systems and between perceptual modalities may potentially modulate the effectiveness of vocabulary acquisition activities during foreign language learning.
3D magnetic seed localization for augmented reality in surgery
Authors: Ambrosini Pierre , AzizianAmiri Sara , Zeestraten Eliane , van Ginhoven Tessa , Marroquim Ricardo , van Walsum Theo 
Published: March 2024

Abstract
Purpose
For tumor resection, surgeons need to localize the tumor. For this purpose, a magnetic seed can be inserted into the tumor by a radiologist and, during surgery, a magnetic detection probe informs the distance to the seed for localization. In this case, the surgeon still needs to mentally reconstruct the position of the tumor from the probe’s information. The purpose of this study is to develop and assess a method for 3D localization and visualization of the seed, facilitating the localization of the tumor.

Methods
We propose a method for 3D localization of the magnetic seed by extending the magnetic detection probe with a tracking-based localization. We attach a position sensor (QR-code or optical marker) to the probe in order to track its 3D pose (respectively, using a head-mounted display with a camera or optical tracker). Following an acquisition protocol, the 3D probe tip and seed position are subsequently obtained by solving a system of equations based on the distances and the 3D probe poses.

Results
The method was evaluated with an optical tracking system. An experimental setup using QR-code tracking (resp. using an optical marker) achieves an average of 1.6 mm (resp. 0.8 mm) 3D distance between the localized seed and the ground truth. Using a breast phantom setup, the average 3D distance is 4.7 mm with a QR-code and 2.1 mm with an optical marker.

Conclusion
Tracking the magnetic detection probe allows 3D localization of a magnetic seed, which opens doors for augmented reality target visualization during surgery. Such an approach should enhance the perception of the localized region of interest during the intervention, especially for breast tumor resection where magnetic seeds can already be used in the protocol.
Short-term outcomes of robot-assisted versus conventional minimally invasive esophagectomy for esophageal cancer: a systematic review and meta-analysis of 18,187 patients
Authors: Perry Rui , Barbosa José Pedro , Perry Isabel , Barbosa José 
Published: March 2024

AbstractThe role of robotic surgery in the curative-intent treatment of esophageal cancer patients is yet to be defined. To compare short-term outcomes between conventional minimally invasive (cMIE) and robot-assisted minimally invasive esophagectomy (RAMIE) in esophageal cancer patients. PubMed, Web of Science and Cochrane Library were systematically searched. The included studies compared short-term outcomes between cMIE and RAMIE. Individual risk of bias was calculated using the MINORS and RoB2 scales. There were no statistically significant differences between RAMIE and cMIE regarding conversion to open procedure, mean number of harvested lymph nodes in the mediastinum, abdomen and along the right recurrent laryngeal nerve (RLN), 30- and 90-day mortality rates, chyle leakage, RLN palsy as well as cardiac and infectious complication rates. Estimated blood loss (MD − 71.78 mL, p < 0.00001), total number of harvested lymph nodes (MD 2.18 nodes, p < 0.0001) and along the left RLN (MD 0.73 nodes, p = 0.03), pulmonary complications (RR 0.70, p = 0.001) and length of hospital stay (MD − 3.03 days, p < 0.0001) are outcomes that favored RAMIE. A significantly shorter operating time (MD 29.01 min, p = 0.004) and a lower rate of anastomotic leakage (RR 1.23, p = 0.0005) were seen in cMIE. RAMIE has indicated to be a safe and feasible alternative to cMIE, with a tendency towards superiority in blood loss, lymph node yield, pulmonary complications and length of hospital stay. There was significant heterogeneity among studies for some of the outcomes measured. Further studies are necessary to confirm these results and overcome current limitations.
Recycling of agro-industrial waste by fabricating laminated Al-metal matrix composites: a numerical simulation and experimental study
Authors: Bandhu Din , Barno Abdullaeva Sayfutdinovna , Ali Eyhab , Fenjan Mohammed N. , Hlail Saif Hameed , Naderian F. 
Published: March 2024

AbstractThe utilization of agriculture waste as a recycling process in aluminium metal matrix composites (AMMCs) has gained significant attention as a novel approach in environmental toxicology. This technique aims to mitigate environmental hazards to humans by reducing the negative impact of waste materials. It has been recognized as an effective means to fabricate and enhance the properties of AMMCs. Furthermore, the use of these agro-industrial waste materials has the potential to mitigate both human and environmental risks, including pollution, while also leading to cost savings in manufacturing processes. The present investigation involves the fabrication of a novel metal matrix composite incorporating rice husk ash particles as reinforcement. The initial phase of the work involved the fabrication of novel composites. Subsequently, the focus shifted towards investigating the mechanical, physical, and wear characteristics of these composites. The forming process of the accumulative rolling was investigated by the numerical simulation using the ABAQUS program. Additionally, this study emphasizes the present utilization and prospective advancements of composites reinforced with agricultural and industrial wastes in diverse sectors, particularly in the fabrication of materials for vessels, autos, and construction industries. Furthermore, an examination of the scanning electron microscopy (SEM) of the fracture surfaces in the vicinity of layer interfaces has been conducted to investigate the quality of bonding.
A systematic review of adolescents’ relationships with siblings, peers, and romantic partners during the COVID-19 lockdown
Authors: Murphy Laila , Bush Kevin R. 
Published: March 2024

AbstractStudies on the pandemic suggest that COVID is related to many facets of adolescent development (i.e., Golberstein et al., JAMA Pediatrics, 174(9), 819–820, 2020). Although the full consequences of COVID on social, economic, and health outcomes are not yet fully known, the impact is predicted to be long-lasting (Prime et al., American Psychologist, 75(5), 631–643, 2020). This paper is a systematic review that focuses on the COVID pandemic’s change in adolescents’ relationships with their siblings, peers, and romantic partners, as well as the role of these relationships in helping adolescents navigate through the uncertainties of this period. Studies from several different countries were selected using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) checklist (Page et al., International Journal of Surgery, 88, 105906, 2021). Overall, the findings are mixed, with some results showing no change or relationship between COVID and each of the adolescent relationships examined, while other results indicated significant positive and/or negative changes or relationships. We hope our review of this growing body of literature will provide guidance and recommendations for researchers moving forward with specific studies examining the change in adolescents’ relationships with siblings, peers, and romantic partners- and the roles of these relationships during the COVID pandemic.
Psychedelic Therapy as Form of Life
Authors: Langlitz Nicolas , Gearin Alex K. 
Published: March 2024

AbstractIn the historical context of a crisis in biological psychiatry, psychedelic drugs paired with psychotherapy are globally re-emerging in research clinics as a potential transdiagnostic therapy for treating mood disorders, addictions, and other forms of psychological distress. The treatments are poised to soon shift from clinical trials to widespread service delivery in places like Australia, North America, and Europe, which has prompted ethical questions by social scientists and bioethicists. Taking a broader view, we argue that the ethics of psychedelic therapy concerns not simply how psychotherapies are different when paired with psychedelic drugs, but how psychedelic therapies shape and are shaped by different values, norms, and metaphysical commitments. Drawing from the published literature and interviews with seven psychedelic therapists working in clinical trials in the United States, Germany, Switzerland, and Australia, this article opens the black box of the treatments to consider the values and informal debates currently animating the therapies. Considering questions of patient autonomy, mechanisms of therapeutic action, and which therapies are best suited to pair with psychedelic substances, we examine the ethics of psychedelic therapy as an emergent form of life. To bring this form of life out in fuller relief, we conclude by comparing and contrasting it with ayahuasca use in Amazonian shamanism.
Predicting the clothing insulation through machine learning algorithms: A comparative analysis and a practical approach
Authors: Aparicio-Ruiz Pablo , Barbadilla-Martín Elena , Guadix José , Muñuzuri Jesús 
Published: March 2024

AbstractSince indoor clothing insulation is a key element in thermal comfort models, the aim of the present study is proposing an approach for predicting it, which could assist the occupants of a building in terms of recommendations regarding their ensemble. For that, a systematic analysis of input variables is exposed, and 13 regression and 12 classification machine learning algorithms were developed and compared. The results are based on data from 3352 questionnaires and 21 input variables from a field study in mixed-mode office buildings in Spain. Outdoor temperature at 6 a.m., indoor air temperature, indoor relative humidity, comfort temperature and gender were the most relevant features for predicting clothing insulation. When comparing machine learning algorithms, decision tree-based algorithms with Boosting techniques achieved the best performance. The proposed model provides an efficient method for forecasting the clothing insulation level and its application would entail optimising thermal comfort and energy efficiency.
Utilization of streamflow rates for determination of precipitation thresholds for landslides in a data-scarce region (Eastern Bartın, NW Türkiye)
Authors: Avcı Pınar , Ercanoglu Murat 
Published: March 2024

AbstractOne of the Türkiye’s most destructive natural hazards is landslides. Although much progress has been achieved in this subject throughout the country, there are still some problems related to adequate meteorological and high-quality landslide data. The aim of this study, which was carried out in the eastern part of Bartın province in the Western Black Sea region of Türkiye, is to indirectly determine the possible threshold values for landslides known to be triggered by precipitation. For this purpose, first, data related to landslides, precipitation, and streamflow were compiled and analyzed. Although many landslides have been mapped in the area, it has been determined that the number of reliable data on the dates (only three exact dates) of landslide occurrences is quite limited in the area. The relationship between the landslides that occurred in 1985, 1998, and 2021, and the stream gauging–precipitation data was analyzed. Then, due to the data scarcity related to the precipitation data, an indirect method, called Soil Conservation Service Curve Number (SCS-CN), was used to determine the relation between runoff and precipitation. The results revealed that daily 80 mm and cumulative 160 mm could be selected as the threshold values that may trigger the landslides. This study serves as an illustration of how an indirect approach can be used to approximate potential precipitation thresholds in a data-scarce region. Therefore, it will be possible to use these precipitation thresholds as a basis for future landslide hazard and risk assessments.
Excluding external iliac node irradiation during neoadjuvant radiotherapy decreases lower intestinal toxicity without compromising efficacy in T4b rectal cancer patients with tumours involving the anterior structures
Authors: Li Anchuan , Mao Miaobin , Chen Runfan , Chi Pan , Huang Ying , Wu Junxin , Xu Benhua 
Published: March 2024

Abstract
Purpose
To explore the impact of excluding the external iliac node (EIN) from the clinical target volume (CTV) during preoperative radiotherapy in T4b rectal cancer with anterior structure invasion.

Methods
We retrospectively identified 132 patients with T4b rectal cancer involving the anterior structures who received radiotherapy followed by surgery between May 2010 and June 2019. Twenty-nine patients received EIN irradiation (EIN group), and 103 did not (NEIN group). Failure patterns, survival and toxicities were compared between the two groups.

Results
The most common failure was distant metastasis (23.5%). 11 (8.3%) patients developed locoregional recurrence, 10 (9.7%) patients were in the NEIN group, and 1 (3.4%) was in the EIN group (P = 0.34). The EIN region failure was rare (1/132, 0.8%). The locoregional recurrence-free survival (LRFS), distant metastasis-free survival (DMFS), overall survival (OS) and progression-free survival (PFS) rates were 96.3% vs. 90.5%, 82.1% vs.73.7%, 75.9% vs. 78.0% and 72.4% vs. 68.3% (all P > 0.05) for the EIN group and NEIN group, respectively. The incidence of grade 3–4 acute toxicity in the lower intestine was significantly higher in the EIN group than in the NEIN group (13.8% vs. 1.9%, P = 0.02). The Dmax, V35 and V45 of the small bowel was decreased in the NEIN group compared to the EIN group.

Conclusions
Exclusion of the EIN from the CTV in T4b rectal cancer with anterior structure invasion could reduce lower intestinal toxicity without compromising oncological outcomes. These results need further evaluation in future studies.
Comparative Antibacterial Activity of Clay-Supported Silver Nanoparticles Prepared by Conventional Heating and Microwave Methods
Authors: Motshekga Sarah Constance 
Published: March 2024

AbstractThe synthesis of multifunctional composites still relies on the use of conventional methods. However, these methods are expensive, time consuming and require high volumes of reducing agents which are often toxic. In this study, composites of bentonite-supported silver nanoparticles were prepared comparatively by the conventional heating method and the rapid microwave method; and their antibacterial activity was investigated against Escherichia coli and Staphylococcus aureus. The crystalline nature of the composites was evaluated by X-ray diffraction (XRD), while transmission electron microscope (TEM) coupled with energy-dispersive spectroscope was used for morphology and elemental analysis, respectively. Surface area and pore size analysis of the composites were conducted by the Brunauer, Emmett and Teller analyzer. TEM images revealed successful synthesis of the composites with a better dispersion of the nanoparticles achieved through microwave, where nanoparticle sizes were 6–38 nm and 9–56 nm by the conventional method. It is worth noting that the composites were prepared in less than 30 min using microwave as compared to 2 h of the conventional method. The XRD spectra confirmed the formation of silver and not any other impurities of the metal. These results revealed that, although the two methods are comparable, microwave method is efficient and time saving and can, therefore, synthesize composites with well-dispersed and narrow distributed nanoparticles. The antibacterial results demonstrated that the prepared composites are effective in the inactivation of various bacteria. These composites could be applied in water treatment, wound dressing, packaging, etc.
Production of single cell protein by fungi from different food wastes
Authors: Ahmed Marwa Gamal , Gouda Shaymaa Ahmed , Donia Samah , Hassanein Naziha Mohamed 
Published: March 2024

Abstract
Single-cell protein (SCP) which is derived from agricultural waste has recently drawn increased interest as a substitute source of protein to improve both human and animal nutrition. In this study, pineapple, orange, banana, sugarcane, and garlic wastes were prepared as substrates for SCP production using fungi under a liquid fermentation system. The fermentation conditions (temperature, pH, and nitrogen sources) of the most promising fungal isolates were optimized for maximum SCP production. Results obtained showed that Aspergillus niger with pineapple waste after 10 days gave the highest protein content (9.79 ± 0.11 g/L), followed by Penicillium citrinum with orange waste after 8 days (9.41 ± 0.15 g/L) and Penicillium crustosum with banana waste after 6 days (7.75 ± 0.11 g/L).The optimum fermentation temperature, pH value, and nitrogen source for SCP production were recorded at 30 °C, pH 4.3, and ammonium sulphate with Aspergillus niger; at 30 °C, pH 5.0, and ammonium sulphate with Penicillium citrinum; and at 20 °C, pH 5.0, and ammonium sulphate with Penicillium crustosum. Based on proximate analysis of SCP produced, fat content ranged from 2.74 ± 0.08∼10.73 ± 0.1%, fibers from 4.8 ± 0.18∼9.45 ± 0.15%, carbohydrates from 14.1 ± 0.06∼20.81 ± 0.06%, ash from 4.05 ± 0.05∼16.1 ± 0.2%, total phenols 0.14 ± 0.03∼0.64 ± 0.04%, and total flavonoids 0.09 ± 0.01∼0.55 ± 0.15%. The amino acid profile of SCP showed that all essential amino acids were present in significant amounts. This study recorded some fungal species as SCP producers for the first time and provided a significant amount of protein. Briefly, fungal SCP is a great protein source and other essential nutrients that may be used in food products.

Graphical Abstract
Incidence and risk factors for HIV-tuberculosis coinfection in the Cologne–Bonn region: a retrospective cohort study
Authors: Suárez Isabelle , Rauschning Dominic , Schüller Cora , Hagemeier Anna , Stecher Melanie , Lehmann Clara , Schommers Philipp , Schlabe Stefan , Vehreschild Jörg-Janne , Koll Carolin , Schwarze-Zander Carolynne , Wasmuth Jan-Christian , Klingmüller Angela , Rockstroh Jürgen Kurt , Fätkenheuer Gerd , Boesecke Christoph , Rybniker Jan 
Published: March 2024

Abstract
Purpose
The risk of developing active tuberculosis (TB) is considerably increased in people living with HIV/AIDS (PLWH). However, incidence of HIV/TB coinfection is difficult to assess as surveillance data are lacking in many countries. Here, we aimed to perform a quantitative analysis of HIV/TB coinfections within the Cologne/Bonn HIV cohort and to determine risk factors for active TB.

Methods
We systematically evaluated data of patients with HIV/TB coinfection between 2006 and 2017. In this retrospective analysis, we compared HIV/TB-coinfected patients with a cohort of HIV-positive patients. The incidence density rate (IDR) was calculated for active TB cases at different time points.

Results
During 2006–2017, 60 out of 4673 PLWH were diagnosed with active TB. Overall IDR was 0.181 cases/100 patient-years and ranged from 0.266 in 2006–2009 to 0.133 in 2014–2017. Patients originating from Sub-Saharan Africa had a significantly (p < 0.001) higher IDR (0.694/100 patient-years of observation, 95% CI [0.435–1.050]) in comparison to patients of German origin (0.053/100 patient-years of observation, 95% CI [0.028–0.091]). In terms of TB-free survival, individuals originating from countries with a TB incidence higher than 10/100,000 exhibited a markedly reduced TB-free survival compared to those originating from regions with lower incidence (p < 0.001). In 22 patients, TB and HIV infection were diagnosed simultaneously.

Conclusion
Overall, we observed a decline in the incidence density rate (IDR) of HIV/TB coinfections between 2006 and 2017. Patients originating from regions with high incidence bear a higher risk of falling ill with active TB. For PLWH born in Germany, the observed risk of active TB appears to be lower compared to other groups within the cohort. These findings should be considered when developing TB containment and screening strategies for PLWH in low-incidence countries.