bluuebunny/crossref_metadata_2025_split huggingface dataset:
Outcomes of tricuspid regurgitation after lead extraction
Authors: Shanafelt Colby , Middour Thomas G. , Ibrahim Rand , Leal Miguel , Lloyd Michael S. , Shah Anand D. , Westerman Stacy B. , El‐Chami Mikhael F. , Merchant Faisal M. , Bhatia Neal K. ,   and other members of the Tricuspid Regurgitation after Lead Extraction Group
Published: March 2024

AbstractIntroductionTransvenous leads have been implicated in tricuspid valve (TV) dysfunction, but limited data are available regarding the effect of extracting leads across the TV on valve regurgitation. The aim of this study is to quantify tricuspid regurgitation (TR) before and after lead extraction and identify predictors of worsening TR.MethodsWe studied 321 patients who had echocardiographic data before and after lead extraction. TR was graded on a scale (0 = none/trivial, 1 = mild, 2 = moderate, 3 = severe). A change of >1 grade following extraction was considered significant.ResultsA total of 321 patients underwent extraction of a total of 338 leads across the TV (1.05 ± 0.31 leads across the TV per patient). There was no significant difference on average TR grade pre‐ and postextraction (1.18 ± 0.91 vs. 1.15 ± 0.87; p = 0.79). TR severity increased after extraction in 84 patients, but was classified as significantly worse (i.e., >1 grade change in severity) in only 8 patients (2.5%). Use of laser lead extraction was associated with a higher rate of worsening TR postextraction (44.0% vs. 31.6%, p = 0.04).ConclusionIn our single‐center analysis, extraction of leads across the TV did not significantly affect the extent of TR in most patients. Laser lead extraction was associated with a higher rate of worsening TR after extraction.
“Extremely toxic and evil” reflections on gender identity change efforts by Christian religious leaders: Implications for therapy with transgender and nonbinary clients
Authors: McGeorge Christi R. , Coburn Katelyn O. 
Published: March 2024

AbstractGiven the religious groundings that support the practice of gender identity change efforts (GICE), we sought to explore the beliefs of Christian religious leaders about this practice and their understanding of marginalized gender identities. Nineteen religious leaders mainly from diverse Mainline Christian Protestant traditions were interviewed. Queer theory‐informed thematic analysis revealed two themes related to participants' beliefs about transgender and nonbinary identities: (1) Transgender and nonbinary identities are normative and authentic and (2) God created gender diversity. The analyses also highlighted two themes reflecting the pastors' beliefs about GICE: (1) GICE is harmful and (2) Therapy should affirm transgender and nonbinary identities. Finally, the thematic analysis exploring participants' messages for couple and family therapists could be organized into two themes: (1) Christian religious beliefs do not justify the use of GICE and (2) Therapists should be helpful and not harmful. Implications for couple and family therapists are also discussed.
Early childhood development and nutritional status in urban Ethiopia
Authors: Delbiso Tefera Darge , Nigatu Yakob Desalegn , Tilahun Natan 
Published: March 2024

AbstractEarly childhood development (ECD) is crucial for better health and well‐being throughout life, but few studies have examined how ECD relates to child malnutrition. This is mainly due to lack of reliable and disaggregated data on ECD. We estimated the prevalence of ECD delays (communication, fine motor, gross motor, problem‐solving and personal–social) and examined how different ECD domains were associated with child nutritional status in urban Ethiopia. Using a community‐based cross‐sectional survey design, 627 mother–child (12–36 months old) pairs were included in the study. The ECD was assessed using the Age and Stage Questionnaire (ASQ‐3), and the nutritional status was assessed using anthropometric measurements. The association between the ECD domains and nutritional status was analysed using ordinal logistic regression, adjusting for confounding variables. Delays in ECD domains were common, especially in fine motor domain (41.9%); and more than half of the children were stunted (52.8%). Stunting and underweight were associated with ECD delays, while wasting was not. Accordingly, stunted children were more likely to have worst ECD delays in fine motor (odds ratios [OR] = 1.54; 95% confidence interval [CI]: 1.11; 2.15), gross motor (OR = 1.47; 95% CI: 1.05; 2.04) and problem‐solving (OR = 1.41; 95% CI: 1.02; 1.96) domains compared to non‐stunted children. Similarly, underweight children were more likely to have worse ECD delays in gross motor (OR = 1.91; 95% CI: 1.20; 3.04) and fine motor (OR = 1.90; 95% CI: 1.15; 3.15) domains compared to normal children. Coordinated and targeted ECD interventions, such as nurturing care, should be promoted and implemented widely to improve ECD outcomes and child nutrition.
Who moves first? Resource price interdependence through time‐varying Granger causality
Authors: Esposti Roberto 
Published: March 2024

AbstractThis paper investigates the interdependence among natural resource prices. Commodities belonging to three different groups (energy commodities, metals, agricultural commodities) are considered. The analysis is performed via a battery of time‐varying Granger causality tests. They allow to assess whether price interdependence occurs and to identify the candidate first movers. These tests also allow observing how long and in which subperiods these causality relationships occur. The approach is applied to the monthly prices of 11 natural resources over the 1980–2021 period. Results suggest that interdependence is weak for energy and agricultural commodities and often concerns limited time periods, while it seems stronger and longer lasting among metals. Moreover, if an overall price driver has to be identified, agricultural commodities more than oil seem to be the best candidates.
Water exchange between the Chlorenchyma and the Hydrenchyma and its physiological role in leaves with Crassulacean acid metabolism
Authors: Cabrita Paulo José Vieira 
Published: March 2024

AbstractDirect and non‐destructive measurements of plant‐water relations of plants exhibiting the Crassulacean acid metabolism (CAM) photosynthetic pathway are seldom addressed, with most findings inferred from gas exchange measurements. The main focus of this paper was to study how the water exchange between the chlorenchyma and the hydrenchyma depends on and follows the CAM photosynthetic diel pattern using non‐invasive and continuous methods. Gas exchange and leaf patch clamp pressure probe (LPCP) measurements were performed on Aloe vera (L.) Burm f., a CAM species, and compared to measurements on banana (Musa acuminata Colla), a C3 species. The LPCP output pressure, Pp, of Aloe vera plants follows its diel CAM photosynthetic cycle, reversed to that observed in banana and other C3 species. The four phases of CAM photosynthesis can also be identified in the diel LPCP output pressure, Pp, cycle. The Pp values in Aloe vera are determined by the hydrenchyma turgor pressure, with both parameters being reversely related. A non‐invasive and continuous assessment of the water exchange between the chlorenchyma and the hydrenchyma in CAM plants, namely, by following the changes in the hydrenchyma turgor pressure, is presented. However, showing once more how the LPCP output pressure, Pp, depends on the leaf structure, such an approach can be used to study plant‐water relations in other CAM species with a leaf structure similar to Aloe vera, with the hydrenchyma composing most of the leaf volume.
Multiple resistance to EPSPS and ALS inhibitors in Palmer amaranth (Amaranthus palmeri) identified in Turkey
Authors: Kaya‐Altop Emine , Jabran Khawar , Pala Firat , Mennan Husrev 
Published: March 2024

AbstractAmaranthus palmeri was first reported in Turkey in 2016, and an immediate heavy infestation of the weed was found in fruit orchards and summer crops such as maize, cotton, and sunflower. There have been farmers' complaints about the ineffective control of Palmer amaranth through the use of glyphosate and some sulfonylureas herbicides. Hence, this study aimed to determine the possible herbicide resistance evolution in Palmer amaranth against glyphosate and acetolactate synthase (ALS) herbicides. Seeds of 21 Palmer amaranth populations were collected from five provinces of Turkey where control problems with glyphosate and ALS inhibitors were reported in maize fields. Seeds of certain biotypes categorized as resistant or susceptible were grown to obtain the F2 generation. A single‐dose experiment determined the possible resistance to ALS inhibitors and glyphosate among the 21 populations. Of this, 18 populations were included in the subsequent dose–response experiments due to evident survival. Based on ED50 values from the dose–response experiment, SNU‐04 and ADN‐21 biotypes had the highest resistance index for glyphosate which was more than 7. The biotypes ADN‐21, OSM‐15, and DIR‐09 recorded the highest ED50 value with a resistance index of 9.21–10.35 after nicosulfuron application. Whereas, the biotypes SNU‐04, OSM‐15, and ADN‐21 were with the highest ED50 value and resistance index of 6.41–7.44, after the application of foramsulfuron + iodosulfuron methyl‐sodium. The increase in genomic 5‐enolpyruvylshikimate‐3‐phosphate synthase (EPSPS) copy number has been observed in suspected cases that have been accepted as the molecular basis for the development of resistance against glyphosate. The sequence alignment results for the ALS gene contained Ala122Val and Pro197Arg mutations related to target‐site resistance against ALS herbicides.
A Novel Industrial Software Model for Social Manufacturing
Authors: Shi Haoliang , Dong Huawei , Yang Maolin , Guo Wei , Jiang Pingyu 
Published: March 2024

Abstract
Distinct from the conventional manufacturing paradigm, the functioning of the Social Manufacturing (SocialM) model relies on a vast and dispersed array of social manufacturing resources. SocialM communities/groups emerge autonomously through business interactions, resource self-organization, and production information sharing, all driven by product orders within the SocialM system. This necessitates a more open, distributed, and autonomous software model to facilitate the allocation and operation of social manufacturing resources in support of the SocialM model. Consequently, this paper introduces a novel software development model designed specifically for SocialM. This proposed model employs business interaction software as the system's primary control portal, enabling efficient management of resources and users based on the social manufacturing communities/groups. Additionally, it facilitates the administration and oversight of numerous applications by utilizing an industrial Appstore. Moreover, the paper delves into the technological roadmap for realizing the essential technologies of the software model by integrating multi-agent and Message Queuing Telemetry Transport (MQTT) technologies. A 3D printing task simulation case was employed to demonstrate the model's working principle, which served to confirm the reliability and scalability of the SocialM software, as well as the feasibility of the SocialM theory.
Antibodies from chlamydia-infected individuals facilitate phagocytosis via Fc receptors
Authors: Hybiske Kevin , Paktinat Shahrokh , Newman Katherine , Patton Dorothy , Khosropour Christine , Roxby Alison C. , Mugo Nelly R. , Oluoch Lynda , Ngure Kenneth , Suchland Robert , Hladik Florian , Vojtech Lucia 
Published: March 2024

ABSTRACT

Non-neutralizing functions of antibodies, including phagocytosis, may play a role in
Chlamydia trachomatis
(CT) infection, but these functions have not been studied and assays are lacking. We utilized a flow-cytometry-based assay to determine whether serum samples from a well-characterized cohort of CT-infected and naïve control individuals enhanced phagocytosis via Fc-receptor-expressing THP-1 cells, and whether this activity correlated with antibody titers. Fc-receptor-mediated phagocytosis was detected only in CT+ donors. Phagocytosis generally did not correlate well with antibody titer. In addition, we found that complement from both CT+ and negative individuals enhanced phagocytosis of CT into primary neutrophils. These results suggest that anti-CT antibodies can have functions that are not reflected by titer. This method could be used to quantitively measure Fc-receptor-mediated function of anti-CT antibodies or complement activity and could reveal new immune correlates of protection.
Complete genome sequence of
Bacillus halotolerans
F29-3, a fengycin-producing strain
Authors: Shu Hung-Yu , Chen Chien-Chi , Ku Hsin-Tzu , Wang Chun-Lin , Wu Keh-Ming , Weng Hui-Ying , Liu Shih-Tung , Chen Chyi-Liang , Chiu Cheng-Hsun 
Published: March 2024

ABSTRACT

Bacillus halotolerans
F29-3, a Gram-positive bacterium, is recognized for its synthesis of the antifungal substance fengycin. This announcement introduces the complete genome sequence and provides insights into the genetic products related to antibiotic secondary metabolites, including non-ribosomal peptide synthetase (NRPS), polyketide synthase (PKS), and NRPS/PKS combination.
Crustal evolution of a continental magmatic arc from subduction to collision: A case study in the Gangdese arc, southern Tibetan Plateau
Authors: Zhang Ze-Ming , Ding Hui-Xia , Palin Richard M. , Dong Xin , Tian Zuo-Lin , Li Xiao-Wei 
Published: March 2024

Abstract
Magmatic arcs are the main environment where continental crust is created on the post-Archean Earth; however, how juvenile arc crust evolves into mature continental crust is still controversial. In this study, we report new bulk-rock major and trace elements, Sr-Nd isotopes, and zircon U-Pb ages and Hf isotopes from a large suite of granites collected from the eastern segment of the Gangdese arc, southern Tibetan Plateau, which record a complete history of arc crust evolution from Mesozoic subduction to Cenozoic collision. These new data show that Gangdese crust-derived granites generated during the subduction to collisional stages record significant geochemical changes with age, indicating that the bulk composition, lithological makeup, and thicknesses of the arc crust evolved over time. Here, we propose that the Gangdese arc had a thick juvenile crust with a small volume of ancient crustal components during late-stage subduction of the Neo-Tethys Ocean, a thin juvenile crust with heterogeneously distributed ancient crustal materials during early collision, and a thick juvenile crust with minor proportions of ancient rocks during late collision. This implies that the arc experienced episodes of crustal thickening during the Late Cretaceous and Eocene, interspersed by periods of thinning during the Paleocene and Miocene, and several discrete episodes of partial melting in the lower arc crust, and cycling or recycling of juvenile and ancient crustal materials within the arc crust and between the crust and mantle. We suggest that shallow subduction of the Neo-Tethys during the Late Cretaceous promoted tectonic thickening of the arc crust, partial melting of lower crust, and formation of high Sr/Y granites. After the onset of the Indo-Asian collision, breakoff of the subducted Neo-Tethyan oceanic slab during the Paleocene/early Eocene allowed thinning of the overlying arc crust and generation of granites derived from juvenile and ancient crustal sources. Continued underthrusting of the Indian continental crust and subsequent delamination of thickened lithospheric mantle led to thickening and thinning of the arc crust, respectively, and partial melting of thickened lower crust and generation of high Sr/Y granites during the Oligocene and Miocene. Using the Gangdese as an analogue for post-Archean continental margins, we suggest that the repeated thickening and thinning of arc crust, and associated multistage remelting of the lower arc crust, and material cycling or recycling within the crust and between the crust and mantle from subduction to collision are common processes that drive maturation of juvenile arc crust.
Constraining the provenance of black shales using rare earth elements and neodymium isotopes, Midcontinent United States
Authors: Morris Noah , Potra Adriana , Samuelsen John R. 
Published: March 2024

Abstract
We conducted research to determine neodymium model dates (TDM), εNd values, and the relative proportions of rare earth elements (REEs) of Paleozoic black shales from the Midcontinent United States to constrain their sediment sources. Twenty-one Cambrian to Pennsylvanian shale formations of the Illinois, Cherokee, Forest City, and Arkoma basins, the Ozark Dome, and the Ouachita Mountains were examined. Findings reveal that these midcontinental shales consist primarily of felsic detrital minerals that originated from the craton. The Cambrian Mt. Simon, Eau Claire, and Tunnel City shales of the northern Illinois Basin exhibit REE patterns and Nd isotopic signatures similar to those of the Ordovician Mazarn and Womble shales of the Ouachita Mountains, which indicates derivation from a similar sediment source. Sediment was likely derived from the Superior and/or Trans-Hudson cratonic provinces. The dominant sediment source shifted during deposition of the Middle Ordovician Womble Shale due to the uplift of the Appalachian Mountains during the Taconic orogeny, as suggested by the younger TDM dates, less negative εNd values, and similar REE patterns compared to those of the older Cambrian and Early Ordovician shales. The Grenville province and Appalachian Basin remained the primary sediment source into the Pennsylvanian.
Two pulsed activities of the Emeishan large igneous province in southwestern China inferred from dolomite U-Pb geochronology and significance
Authors: Xiao Di , Huang Tianhai , Xu Qiang , Tan Xiucheng , Wen Long , Zheng Jianfeng , Cao Jian 
Published: March 2024

Abstract
The Emeishan large igneous province (ELIP) was a major geological event that took place around the Middle–Late Permian boundary. The major episode of the ELIP is generally considered to have occurred at 260–259 Ma, although an increasing number of geological data have suggested that multiple episodes of magmatic activity might have occurred. Here we report a study of a Lower Permian dolomite whose formation was influenced by the ELIP in the Sichuan Basin of southwestern China. Results show two new pulsed activities at 273.2 ± 9.7 Ma to 269.1 ± 12.0 Ma (ELIP-I) and 263.2 ± 10.3 Ma to 258.7 ± 8.1 Ma (ELIP-II). The two stages of the ELIP magmatism and thermal activity controlled the regional tectonic, sedimentary, and diagenetic evolution and exerted a profound influence on the oil and gas reservoirs, source rocks, and lithofacies paleogeography. This study is the first to interpret the timing of the ELIP from analysis of hydrothermal dolomite and provides new clues and data for improving our understanding of the dynamic formation mechanism and Earth system of the ELIP.
Carboniferous to Triassic polyphase tectonic transition in the western North China craton: A retroarc basin response to termination of the middle segment of the Paleo-Asian Ocean
Authors: Sun Jiaopeng , Dong Yunpeng , Zhao Junfeng , Chen Qiang 
Published: March 2024

Abstract
Knowledge of the closure of the archipelago-type southern Paleo-Asian Ocean has been limited by uncertainty regarding whether the Alxa tectonic belt was isolated from the North China craton by an ocean around the Helanshan tectonic belt. Newly released seismic reflection profiles across the Alxa-Ordos border showed that the Alxa tectonic belt and Ordos Basin were located in a paleogeographically linked basin throughout the Paleozoic, indicating that the Tianshan and Solonker sutures were contiguous. The ca. 320–285 Ma successions in the Helanshan tectonic belt and surroundings, fed by a northeasterly Inner Mongolia continental arc source, display a retrogradational stacking pattern along with diabase sill emplacement. This inferred retroarc extensional setting was coeval with asthenospheric upwelling and thinning of the continental arc driven by retreating subduction of the Paleo-Asian Ocean. The subsequent ca. 280–260 Ma sedimentary hiatus coincided with magmatic flare-up, crustal thickening, and retroarc foreland formation in the Inner Mongolia continental arc, indicating a geodynamic transition from retroarc extension to compression in the mid-Permian. Then craton-scale drainage reorganization occurred during the Early Triassic (ca. 250–230 Ma), manifested by the discharge of the Middle Triassic fluvial system southeastward to the central Ordos Basin; this was steered by southeastward expansion of the Alxa tectonic belt during the final termination of the Paleo-Asian Ocean. Postcollision lithospheric adjustment since ca. 230 Ma resulted in vigorous alkaline magmatism and supracrustal stretching in the Inner Mongolia continental arc as well as mafic magmatism and rifting in the study area. Hence, Carboniferous to Triassic polyphase tectonic transitions in the western North China craton were retroarc basin expressions related to complicated subduction-closure processes in the southern Paleo-Asian Ocean.
On Universal Sampling Recovery in the Uniform Norm
Authors: Temlyakov V. N. 
Published: March 2024

Abstract
It is known that results on universal sampling discretization of the square norm are useful in sparse sampling recovery with error measured in the square norm. In this paper we demonstrate how known results on universal sampling discretization of the uniform norm and recent results on universal sampling representation allow us to provide good universal methods of sampling recovery for anisotropic Sobolev and Nikol’skii classes of periodic functions of several variables. The sharpest results are obtained in the case of functions of two variables, where the Fibonacci point sets are used for recovery.
Comparing the frequency of variants of uncertain significance (VUS) between ancestry groups in a paediatric epilepsy cohort
Authors: Martin Bree E , Sands Tristan , Bier Louise , Bergner Amanda , Boehme Amelia K , Lippa Natalie 
Published: March 2024

Background
Studies indicate that variants of uncertain significance are more common in non-European populations due to lack of a diversity in population databases. This difference has not been explored in epilepsy, which is increasingly found to be genetic in paediatric populations, and has precision medicine applications. This study examines the differences in the frequency of uncertain next-generation sequencing (NGS) results among a paediatric epilepsy cohort between ancestral groups historically under-represented in biomedical research (UBR) and represented in biomedical research (RBR).

Methods
A retrospective chart review of patients with epilepsy seen at Columbia University Irving Medical Center (CUIMC). One hundred seventy-eight cases met the following criteria: (1) visited any provider within the Pediatric Neurology Clinic at CUIMC, (2) had an ICD code indicating a diagnosis of epilepsy, (3) underwent NGS testing after March 2015 and (4) had self-reported ancestry that fit into a single dichotomous category of either historically represented or under-represented in biomedical research.

Results
UBR cases had significantly higher rates of uncertain results when compared with RBR cases (79.2% UBR, 20.8% RBR; p value=0.002). This finding remained true after controlling for potential confounding factors, including sex, intellectual disability or developmental delay, epilepsy type, age of onset, number of genes tested and year of testing.

Conclusion
Our results add to the literature that individuals who are of ancestries historically under-represented in genetics research are more likely to receive uncertain genetic results than those of represented majority ancestral groups and establishes this finding in an epilepsy cohort.