bluuebunny/crossref_metadata_2025_split huggingface dataset:
Employment Negotiations With an Algorithm? How AI as Negotiation Counterpart Would Affect Negotiators' Trust and Subjective Value Expectations
Authors: Sondern Dominik , Arnholz Nadine , Hertel Guido 
Published: February 2025

ABSTRACTArtificial intelligence (AI) offers manifold ways to improve organizational recruiting and conflict resolution due to high processing power and low subjective biases. Additionally to AI applications approaching and selecting job applicants, AI usage might also be promising in employment negotiations as the final step of recruitment. However, it is largely unclear how applicants would react to the use of AI technology in such a context marked by high stakes and (at least partly) conflicting interests, which need to be resolved to terminate the recruitment process successfully. Therefore, we examined how AI negotiation agents influence negotiators' trust in and expectations about an upcoming employment negotiation. In a preregistered experimental vignette study, participants (n = 291) imagined to prepare for an employment negotiation. Varying the type of negotiation counterpart (human—AI with avatar—AI without avatar), we assessed participants' trust intentions and subjective value expectations regarding the anticipated negotiation. We found higher trust and more positive expectations for human counterparts as compared to AI counterparts, regardless of whether the AI was presented with or without an avatar. However, participants' technology‐related attitudes and skills attenuated this effect, leading to less negative effects for AI as a negotiation counterpart when participants possessed high skills and positive attitudes regarding digital technologies. Overall, this study provides initial evidence of how people would react to AI agents in mixed‐motive and conflict resolution settings and may serve as a starting point for developing evidence‐based guidelines for designing AI agents for HR and conflict resolution settings.
Cordycepin Ameliorates Kainic Acid‐Induced HT22 Cell Neurotoxicity by Activating GPR120‐Mediated Mitophagy
Authors: San Yongzhi , Wang Minghua 
Published: February 2025

ABSTRACTBackgroundMitophagy is important for normal neural activity. Epilepsy is intimately linked to neurotoxicity due to mitochondrial dysfunction. Cordycepin (Cor) has been shown to exert neuroprotective effects. This study aims to investigate whether Cor could mitigate neurotoxicity in epilepsy by modulating mitophagy.MethodsIn vitro, kainic acid (KA) was utilized to induce cytotoxicity in HT22 cell. Cell viability was assessed using the CCK‐8 assay, while cell damage was evaluated through an LDH kit. Flow cytometry was used to assess apoptosis. The expressions of G protein‐coupled receptor 120 (GPR120), apoptosis, and mitophagy‐related proteins were analyzed by western blot. Inflammatory factors and oxidative stress levels were examined by kits. DCFH‐DA staining was applied to observe cellular reactive oxygen species (ROS) levels. The three‐dimensional coordinates of GPR120 were retrieved from the PDB database, and molecular docking was performed using AutoDock. Immunofluorescence staining was used to observe mitophagy level.ResultsCor significantly attenuated KA‐induced HT22 cell viability injury and inflammation, while suppressing ROS and oxidative stress levels. Notably, Cor ameliorated the decrease of mitophagy level observed in HT22 cells treated with KA. GPR120 expression was upregulated following KA treatment and further elevated after adding Cor. Cor could bind to GPR120. Interference with GPR120 reversed the ameliorative effects of Cor on KA‐induced mitophagy and cytotoxicity in HT22 cells.ConclusionOverall, Cor significantly alleviated KA‐induced HT22 cell neurotoxic damage and oxidative stress. This protective effect may be mediated through GPR120‐regulated mitophagy.
A Reassessment of Phylogenetic Relationships in Class Oligohymenophorea (Protista, Ciliophora) Based on Updated Multigene Data
Authors: Li Bailin , Song Yumeng , Wang Xiang , Zhao Qiyue , Liu Menghan , Liu Lihui , Pan Xuming , Yi Zhenzhen 
Published: February 2025

ABSTRACTWithin the ciliate class Oligohymenophorea, many evolutionary relationships among taxa remain unresolved. This study incorporates 97 new sequences from 30 oligohymenophorean populations, including nuclear small subunit ribosomal (SSU‐rRNA) genes, nuclear ITS1‐5.8S‐ITS2 rRNA regions, nuclear large subunit ribosomal (LSU‐rRNA) genes, mitochondrial cytochrome oxidase c subunit I (cox 1) genes, and mitochondrial small subunit ribosomal RNA (mtSSU‐rRNA) genes. With the addition of these new sequences, we performed comprehensive multigene phylogenetic analyses of Oligohymenophorea. The main findings are: (1) Utilizing multiple genes is instrumental in improving phylogenetic relationships within class Oligohymenophorea; (2) class Oligohymenophorea is divided into two distinct groups: (i) encompassing the subclass Hymenostomatia, Scuticociliatia, Apostomatia, Astomatia, and Urocentria; and (ii) comprising the subclasses Peniculia and Peritrichia; (3) Revising the phylogenetic placement of the subclass Urocentrida reveals its transitional role as a taxon between Group I and Group II. It emerges as a sister clade to Hymenostomatia; (4) the phylogenetic positions of Astomatia and Apostomatia within the clade ‘SAA’ become clearer; and (5) the order Loxocephalida represents an early member of Scuticociliatia and serves as a potential prototype for this taxonomic group. This study provides more information for understanding the evolutionary relationships within Oligohymenophorea.
Sex‐Specific Ultraviolet Radiation Tolerance Across Drosophila
Authors: Titus‐McQuillan James E. , Turner Brandon A. , Rogers Rebekah L. 
Published: February 2025

ABSTRACTThe genetic basis of phenotypic differences between species is a longstanding question in evolutionary biology. How new genes form and selection acts to produce differences across species are fundamental to understanding how species evolve. Adaptation and genetic innovation arise in the genome from a variety of sources. Functional genomics requires both genetic discoveries and empirical testing to observe adaptation between lineages. We explore two species of Drosophila from the island of São Tomé and mainland Africa, D. santomea and D. yakuba. These two species have varying distributions based on elevation on São Tomé, with populations of D. yakuba also inhabiting mainland Africa. Genomic/genetic evidence shows genes between species may have a role in adaptation to higher UV tolerance. We conducted empirical UV assays between D. santomea and both D. yakuba populations. Flies were shocked by UVB radiation for 30 min on a transilluminator apparatus. Custom 5‐wall acrylic enclosures were constructed for viewing and containment of flies. Island groups show significant differences between fall‐time under UV stress and recovery time post‐UV stress test between populations and by sex. This study shows evidence that mainland flies are less resistant to UV radiation than their island counterparts. Differential expression analysis also shows potential for new mutations and local adaptation for DNA repair of D. santomea. Understanding the mechanisms and processes that promote adaptation and testing traits within the context of the genome is crucially important to understand evolutionary machinery.
Multiscale spatial dependency of small mammal diversity patterns and their determinants
Authors: Onditi Kenneth Otieno , Song Wenyu , Chen Zhongzheng , Li Xueyou , Li Quan , de la Sancha Noé U. , Musila Simon , Jiang Xuelong 
Published: February 2025

AbstractAnimals perceive their ecosystems at multiple spatial scales such that the pattern–process relationships that determine their ecological and evolutionary opportunities are also spatially variable. Understanding how spatial scale impacts our observations of ecological and evolutionary patterns and processes is therefore crucial for effective biodiversity management. In this study, using a comprehensive dataset of small mammals from primary field surveys supplemented with literature data across Kenya, we investigated the effects of spatial scale on the distribution patterns of taxonomic, phylogenetic, and functional diversity indices. We also tested how relationships between taxonomic, phylogenetic, and functional diversity and various environmental and anthropogenic variables change across spatial scales. The results showed that with increasing spatial scale, species richness and phylogenetic and functional richness consistently increased. Community‐wide mean pairwise distance indices for phylogenetic and functional dimensions also increased, while fine‐scale mean nearest taxon distance indices decreased. Notably, community structure indices exhibited nonmonotonic patterns across spatial scales. The associations between diversity patterns and environmental and human covariates increased with scale but were more variable and complex across regions. These findings highlight a negative correlation between spatial scale and phylogenetic and functional divergence while reinforcing the species‐area hypotheses for richness‐dependent diversity indices. Identifying the optimal scales of field studies and conservational actions must factor in the species group of interest and the geographical context.
TSCH in Edge IoT: A Comprehensive Survey of Research Challenges
Authors: Rekha D. , Pavithra L. 
Published: February 2025

ABSTRACTTime‐slotted channel hopping (TSCH) is a promising approach for efficient communication in Internet of Things (IoT) networks, with its significance extending to the emerging landscape of Edge computing. This survey article investigates TSCH within the framework of IoT, exploring its advantages, challenges, and applications. TSCH divides time into slots and dynamically hops between channels, enabling multiple devices to share the same frequency band while mitigating interference. The study aims to address existing research issues and motivations by providing an innovative methodology for examining TSCH's role in IoT communication. The benefits of TSCH, such as improved reliability, energy efficiency, and scalability, are discussed, alongside the challenges associated with its implementation in IoT networks, including synchronization, channel selection, slot allocation, and the energy‐performance trade‐off. Various techniques and algorithms proposed in the literature to tackle these challenges are reviewed, offering a comprehensive analysis of their effectiveness. The potential applications of TSCH in domains like smart homes, industrial automation, smart grids, and healthcare are explored, with a focus on the unique requirements and characteristics of each domain. How TSCH can effectively address the communication needs of these applications is highlighted. Performance evaluation of TSCH in IoT networks is presented through a review of existing studies, simulation models, and experimental deployments. Key performance metrics, such as packet delivery ratio, latency, energy consumption, and network capacity, are discussed. The paper concludes by summarizing the key findings and emphasizing TSCH's impact on IoT communication protocols. This paper serves as a valuable resource for researchers and practitioners involved in IoT communications, providing insights into TSCH's benefits, challenges, and applications in IoT networks.
Purple Yam Anthocyanin Forestalling Lipopolysaccharide‐Induced Intestine Damage by Selectively Promoting Lactococcus
Authors: Qiu Pingfei , Wang Qin , Li Xiaochun , Bao Ruiying , Cai Qingying , Peng ZeRu , Huang LiangMin , Shi Huiyu , Zhang Haiwen , Wang Xuemei 
Published: February 2025

ABSTRACTThe mechanism of anthocyanin in alleviating intestine injury of pigs is worth pursuing due to the higher similarity of physiological structure between human beings and pigs than rodents. Herein, we investigated the mechanism by which anthocyanin improves gut damage induced with lipopolysaccharide and further confirmed this mechanism using fecal microbiota transplantation. Thirty‐two piglets were randomly divided into four treatments: control group (Control), model group (LPS), prophylactic anthocyanin group (An‐LPS), and prophylactic fecal microbiota transplantation group (FMT‐LPS). The results showed that oxidative stress induced by lipopolysaccharide increased the expression of p‐p65, Bax, and Keap1 and decreased the expression of Nrf2, Occludin, and Claudin‐1 in jejunum. However, anthocyanin and its fecal microbiota suspension reversed these influences. Meanwhile, anthocyanin selectively improved certain microbiota, including Lactococcus, leading to distinct metabolic profiles. These differences were in favor of activating antioxidant‐related signaling pathway, including Nrf2/Keap1 and inhibiting pro‐inflammatory signaling pathway such as NF‐κB, which alleviated gut inflammation and significantly increased the expression of intestinal tight junction, such as Occludin and Claudin‐1. Moreover, compared to LPS, the serum antioxidant enzyme activity and IL‐10 content were increased in An‐LPS. In conclusion, anthocyanin ameliorated gut oxidative stress through antioxidant‐ and inflammation‐related signaling pathways; meanwhile, gut microbiota and metabolites play a nonsubstitutable role in this process.
Allergic Potential of Medicinal Plants From the Asteraceae Family
Authors: Ključevšek Tim , Kreft Samo 
Published: February 2025

ABSTRACTBackground and AimsThe popularity of herbal medicine continues to increase in modern health care practices; therefore, it is imperative to recognize and address potential risks associated with its everyday use. The Asteraceae family is one of the most extensively utilized medicinal plant families due to its abundance and diversity of bioactive secondary metabolites. The aim of this article is to review the current understanding of the allergic potential of the most significant medicinal plant species belonging to the Asteraceae family.MethodsThis review utilized various search engines, including PubMed Central, Cochrane Central, Google Scholar, and others, up to January 2024, considering only articles in English.ResultsAsteraceae have long been acknowledged as important sensitizers within occupational environments, eliciting both immediate and delayed hypersensitivity reactions. Recent investigations have indicated the presence of panallergens in Asteraceae pollen, predominantly identified in Ambrosia artemisiifolia and Artemisia spp., which are pervasive across many species within the family. These panallergens contribute to cross‐reactivity phenomena, serving as primary triggers for pollinosis and pollen‐food or pollen‐medicine allergy syndrome. In addition, the diverse array of secondary metabolites present in the Asteraceae family, particularly sesquiterpene lactones (SLs), possesses sensitizing properties capable of inducing skin irritation and inflammation. Moreover, SLs have the potential to incite systemic reactions, posing a risk to sensitized individuals upon ingestion. Although extensive cross‐reactivity among SLs has been reported, further investigations are warranted to elucidate the underlying mechanisms and implications.ConclusionAs numerous uncertainties persist regarding critical Asteraceae allergens and sensitizers further research is critical to augment our understanding of the potential risks posed by Asteraceae herbal medicine.
Neuromuscular Blocking Agents and Tracheal Intubation: Systematic Review and Meta‐Analysis of Effects on Laryngeal Complications and Intubating Conditions
Authors: Li Wanhong , Lin Zhongyuan , Li Fen , Huang Kecheng , Dou Yunling , Fang Jieyu 
Published: February 2025

ABSTRACTBackground and AimsThe use of neuromuscular blocking agents (NMBAs) in tracheal intubation is widely accepted in anesthetic induction, but adverse effects are possible. We performed a systematic review and meta‐analysis to compare influence of use and nonuse of NMBAs on incidence of laryngeal complications and intubating conditions in surgical patients.MethodsWe searched PubMed, Web of Science, Embase, and Cochrane Library for randomized controlled trials comparing use of NMBAs with either placebo or no treatment for oral tracheal intubation in adult patients under general anesthesia. Studies were evaluated using a risk‐of‐bias assessment. We conducted random‐effects or fixed‐effects meta‐analyses on extracted data and calculated risk ratio (RR), risk difference (RD), and 95% confidence interval (CI).ResultsNine trials with 1176 participants were included. Incidence of postoperative sore throat or hoarseness did not differ between groups receiving and not receiving NMBAs at 24 h (RR: 1.18; 95% CI: 0.96–1.46; I2 = 45%), 48 h (RR: 0.84; 95% CI: 0.46–1.52; I2 = 42%), or 72 h (RD: −0.00; 95% CI: −0.08 to 0.07; I2 = 59%). Compared with use of NMBAs, induction without NMBAs reduced the occurrence of acceptable intubating conditions (RR: 0.80; 95% CI: 0.67–0.94; I2 = 92%) and with increased risk for poor intubating conditions (RR: 4.77; 95% CI: 3.20–7.10; I2 = 0%). The pharmacological interventions for hemodynamic changes after intubation did not differ significantly between the NMBAs and non‐NMBAs groups (RR: 1.02; 95% CI: 0.53–1.95; I2 = 78%).ConclusionEndotracheal intubation without NMBAs does not increase the incidence of postoperative hoarseness or sore throat in adult surgical patients, which may be considered as a safe and effective technique of anesthesia induction. Although NMBAs use was associated with acceptable intubating conditions and reduced risk for poor intubation conditions.Trial RegistrationPROSPERO CRD42021284813
Both medial closing wedge and lateral opening wedge distal femoral osteotomy for valgus knee deformity can maintain leg length: A radiographic comparative study
Authors: Onishi Shintaro , Kim Youngji , Adebayo Oliver , Nakayama Hiroshi , Jacquet Christophe , Ollivier Matthieu 
Published: February 2025

AbstractPurposeTo compare the radiological outcomes of medial closed wedge distal femoral osteotomy (MCWDFO) and lateral open wedge distal femoral osteotomy (LOWDFO), with a focus on evaluating leg length discrepancy (LLD). It was hypothesised that MCWDFO would result in a greater reduction in leg length compared to LOWDFO.MethodsPatients who underwent MCWDFO or LOWDFO for valgus deformity at a single institution between 2014 and 2022 with a minimum follow‐up of 1 year were included. Radiological assessment included hip–knee–ankle (HKA) angle, mechanical lateral distal femoral angle (mLDFA), medial proximal tibial angle (MPTA), length of the whole leg and femur and LLD. The difference between pre‐ and post‐operative values for each parameter is expressed as Δ. The radiological outcomes were statistically evaluated for each procedure.ResultsFifty‐two patients (26 MCWDFO and 26 LOWDFO) were included. No significant differences were observed between the two groups with respect to demographic data and radiological parameters such as HKA, mLDFA and MPTA. Although Δ length of the femur decreased post‐MCWDFO (−2.7 ± 0.6 mm) and increased post‐LOWDFO (+2.7 ± 0.4 mm), the Δ length of the whole leg post‐MCWDFO decreased (−0.5 ± 3.8 mm) and increased post‐LOWDFO (+1.7 ± 2.6 mm) (p < 0.001). The straight‐lengthening effect on the length of whole leg was significantly greater in MCWDFO than in LOWDFO (+2.0 ± 4.1 mm vs. −1.1 ± 2.5 mm, p > 0.001).ConclusionsThe straight‐lengthening effect of alignment correction minimises changes in overall leg length, regardless of the specific DFO technique.Level of EvidenceLevel III, retrospective comparative study.
Can CMIP6 Models Accurately Reproduce Terrestrial Evapotranspiration Across China?
Authors: Shen Hui , Li Jianduo , Wu Guocan , Ye Aizhong , Mao Yuna 
Published: February 2025

ABSTRACTTerrestrial evapotranspiration (ET) plays a fundamental role in the climate system. The Coupled Model Intercomparison Project Phase 6 (CMIP6) provides a valuable framework for assessing global climate model performance, but gaps remain in evaluating its ET estimates, particularly in China. To fill this gap, we employed the Global Land Evaporation Amsterdam Model (GLEAM) and the water balance ET method to validate the CMIP6 ET outputs from 1980 to 2014 at both national and river basin scales. Key findings include: (1) GLEAM ET performs comparably to the water balance method, making it reliable for validating CMIP6 ET outputs. From 1980 to 2014, the annual mean ET in GLEAM for China ranges from 355 to 411 mm/year. In contrast, most CMIP6 models overestimate ET, with the multi‐model ensemble (MME) mean ranging from 524 to 542 mm/year, showing considerable variation among models. Spatially, the MME overestimates ET across over 90% of China. Bayesian model averaging (BMA) results align closely with reference data, with overestimation concentrated in southwest China. (2) At the national scale, CMIP6 trends range from −0.36 to 0.58 mm/year2, which contrasts sharply with the GLEAM trend of 1.27 mm/year2. At the basin scale, most models overestimate annual ET compared to GLEAM, with discrepancies particularly evident in the major river basins. The smallest difference in ET trend simulation occurs in the Northwest River basin, where model distributions are more concentrated, while the largest discrepancies appear in the Pearl River basin, where model performance is more scattered. Furthermore, signal‐to‐noise ratio (SNR) analysis reveals high ensemble consistency in regions such as the Haihe, Yellow, Yangtze, Pearl and Songliao River basins, indicating more reliable model performance in these areas. This study contributes to enhancing the reliability and accuracy of climate projections, which is essential for informed decision‐making and policy formulation in atmospheric science.
Landmarks to guide femoral insertion in lateral patellofemoral ligament reconstruction: An in vivo assessment of isometry
Authors: Boot Miriam R. , van de Groes Sebastiaan A. W. , Tanck Esther , Janssen Dennis 
Published: February 2025

AbstractPurposeLateral patellofemoral ligament (LPFL) reconstruction addresses medial patellar instability, but uncertainty regarding the optimal femoral attachment site may affect isometry and increase complication rates. This study aimed to establish landmarks for the femoral attachment of the LPFL graft based on in vivo isometry during active knee extension.MethodsDynamic computed tomography scans of 104 knees from 58 healthy participants were employed to examine flexion‐extension movements. Length changes were assessed in approximately 1335 virtual LPFL graft fibres, which extended from the proximal one third of the patellar height to attachments across the femoral condyle. Four methods were evaluated for achieving (near‐)isometric LPFL graft behaviour: three radiographic methods (R1–R3) and one anatomic method (A). Method R1 positioned the femoral attachment at a lateral equivalent of Schöttle's point, Method R2 at the centre of the trochlear groove arc, Method R3 at the centre of the lateral trochlear ridge arc and Method A at a point relative to the lateral epicondyle.ResultsMedian length changes during extension were 7.7 mm (Method R1), 3.4 mm (Method R2), 2.7 mm (Method R3) and 3.0 mm (Method A). Method R3 demonstrated significantly smaller length changes compared to Methods R1 (p < 0.001) and R2 (p < 0.01), while Method A yielded smaller changes than Method R1 (p < 0.001). Notably, Method R1 resulted in continuous LPFL graft tightening throughout knee motion, whereas Methods R2, R3 and A showed initial tightening until 20° flexion, followed by slackening and near‐isometric behaviour.ConclusionFemoral graft attachment is best determined at the centre of the lateral trochlear ridge arc (Method R3) or 15.1 mm anterior and 3.4 mm proximal to the lateral epicondyle (Method A). These guidelines help improve surgical precision and minimize complications in LPFL reconstructions.Level of EvidenceLevel III.