bluuebunny/crossref_metadata_2025_split huggingface dataset:
Preliminary experience in pelviscopic uterine suspension using Webster‐Baldy and Franke's method
Authors: Koh Lim‐Woh , Tang Francisco C. , Huang Ming‐Huo 
Published: November 2007

Objective. To find which method gives the best relief from dyspareunia and pelvic pain caused by a retroverted uterus using the two methods mentioned as compared to other methods reported in the medical literature.Subjects. Twenty‐five patients, with ages ranging from 25‐55 years old, complaining of mild to severe pelvic pain and dyspareunia seeking treatment in our OPD were evaluated and treated in a span of 3 years' time.Methods. Pelviscopic retrouterine ligament fixation using Webster‐Baldy and Franke's method were done after each patient was evaluated as to the uterine position, degree of misalignment of the uterus and severity of adhesion. Pelvic pain and dyspareunia were reproduced by palpation of the retroverted uterus. Ultrasonographies were performed to confirm initial findings and to rule out any ovarian or uterine abnormalities. Orthopedic and psychological consultations were done to rule out any orthopedic disorders or non‐organic causes of their problem.Results. Of the twenty‐five patients treated, 20 patients were treated using Webster‐Baldy method and five patients were treated using Franke's method, all the patients (100%) experienced great improvement 6 weeks after the operation. After 6 months, 16 patients (80%) with the Webster‐Baldy method and four patients (80%) with the Franke's method had complete relief from pelvic pain and dyspareunia. The remaining four patients (20%) with the former method and one patient (20%) with the latter method complained of mild abdominal discomfort. After 6 months to 2 years of follow‐up, 17 patients with Webster‐Baldy method and five patients with Franke's method (88%) had improved sexual life and the remaining three patients were lost to follow‐up.Conclusion. When dyspareunia and pelvic pain are caused by a retroverted method, we believe uterine suspension using different procedures will certainly relieve this problem. We have presented and have chosen these two procedures mainly due to their simplicity and the almost nil possibility of bowel intussusception into the anterior cul‐de‐sac as compared to other methods.
Uterine artery color Doppler assisted veloeimetry and perinatal outcome
Authors: Hofstaetter Cornelia , Dubiel Mariusz , Gudmundsson Sæmundur , Marsal Karel 
Published: November 2007

Background. Previously, we have found uterine artery blood veloeimetry performed with Doppler ultrasound without vessel visualization to be a poor predictor of perinatal outcome. The aim of this study was to ascertain whether the combination of color Doppler imaging with the method would improve its predictive value.Methods. In a cross‐sectional study of 110 uncomplicated pregnancies, uterine artery blood velocity was recorded bilaterally from 18 to 42 weeks of gestation to obtain reference values for pulsatility index (PI). Using color Doppler imaging, the main uterine artery was located as it crosses the iliac vessels and blood velocity was then recorded with pulsed Doppler ultrasound. The uterine and umbilical blood velocity waveforms were also obtained in 421 complicated pregnancies, and the results related to placental site and perinatal outcome.Results. In uncomplicated pregnancies, the uterine artery PI was unrelated to gestational age using 1.20 as the upper cut‐off limit for the mean PI of both vessels (mean+2 s.d.). Corresponding values for unilateral placental localization were 1.00 at the placental side and 1.40 at the non‐placental side. Blood velocities obtained using the color Doppler combination were similar to previously presented results. In the complicated pregnancies, significant correlation was found between abnormal perinatal outcome and abnormality of the uterine artery blood velocity waveform, either increased PI (n=44) or a notch in early diastole (n=92). The predictive value of an early diastolic notch was superior to an increased PI in predicting abnormal outcome. The mean PI for both uterine arteries was a better predictor of outcome than blood velocity on the placental side. The blood velocity waveforms on the non‐placental side were the poorest predictors of outcome.Conclusion. The addition of color Doppler imaging to pulsed wave Doppler ultrasound recording of uterine artery blood velocity improves the predictive value of blood velocity waveforms with regard to the perinatal outcome.
Transvaginal sonographic measurements of postmenopausal ovarian volume as a possible detection of ovarian neoplasia
Authors: Zalel Yaron , Tepper Ron , Altaras Marco , Beyth Yoram 
Published: November 2007

Background. The purpose of our study was to determine whether ovarian volume, as measured by transvaginal ultrasound and plotted on the nomogram of normal postmenopausal ovarian volume, could assist in the diagnosis of ovarian neoplasia.Methods. A retrospective study was undertaken, in which the ovaries of 85 postmenopausal women were examined by transvaginal ultrasonography prior to laparotomy. Three dimensions of each ovary were measured and ovarian volume was calculated. The results were plotted on the nomogram of normal postmenopausal ovarian volume.Results. Eighty‐five ovarian tumors were diagnosed. The range of the mean ovarian volume varied between 98.15 cm3 to 161.81 cm3 from perimenopausal age to >15 postmenopausal years, as compared to 2.21.4 − 8.6±2.8 cm in the normal postmenopausal women. The deviation from the normal volume was more striking in the malignant tumors group (100%) than in the benign group (86%). When plotted on the nomogram, these values showed significant deviation (above 2 s.d.) from the norm for each group of neoplasms in every menopausal age.Conclusions. Sonographic detection of abnormal postmenopausal ovarian volume and the demonstration of the deviation from the ovarian volume nomogram, could assist the physician in early diagnosis of ovarian neoplasia. Ovarian volume measurements can serve as the primary method leading to diagnosis of ovarian cancer.
Diagnostic accuracy of 2 mm microlaparoscopy
Authors: Haeusler Guenther , Lehner Rainer , Hanzal Engelbert , Kainz Christian 
Published: November 2007

Objective. To assess the diagnostic accuracy of a 2 mm microlaparoscope compared to the conventional 10 mm laparoscope.Design. A prospective study.Patients and methods. Fifty‐two patients underwent 2 mm and 10 mm laparoscopy in the same session. All procedures were videotaped and the quality of visualization for both methods was assessed by an independent investigator using a 3‐step grading scale.Results. Diagnostic information was found to be similar for both methods.Conclusion. In most cases undergoing laparoscopy for diagnostic purposes 2 mm microlaparoscopy yields sufficient information to abandon the conventional 10 mm technique.Fifty‐two patients were laparoscoped with the 2 mm and the 10 mm system in the same session. Diagnostic information was found to be similar for both methods. The present study demonstrated that in most cases 2 mm microlaparoscopy yields sufficient information to abandon the conventional 10 mm technique.
Expression of interleukin‐8 receptors in the gestational tissues before and after initiation of labor: Immunohistochemical study
Authors: Maradny Emad El , Kanayama Naohiro , Maehara Kayoko , Kobayashi Takao , Terao Toshihiko 
Published: November 2007

Background. Interleukin‐8 (IL‐8) has an essential role in the mechanism of parturition. IL‐8 induces its effect through specific cell binding receptors. The main purpose of this research was to elucidate the presence of IL‐8 receptors in the gestational tissues and their relation to parturition.Materials and methods. Fetal membranes, placenta, umbilical cord and myometrial samples were collected before the initiation of labor during elective Cesarean sections (n=15). Similar biopsies (except myometrial samples) were also gathered after normal vaginal delivery (n= 15). Immunohistochemical staining for IL‐8 receptors type I and II was carried out for the fresh frozen sections of all samples. Immunoreactive score (IRS) was calculated for the stained sections.Results. IL‐8 Receptors type I and II were recognized in the fetal membranes, placenta, umbilical cord and myometrial samples collected from patients before the initiation of labor. The staining of amnion and placentas were found to be more intensified in the samples collected after vaginal delivery compared to those from elective cesarean sections and before initiation of labor.Conclusions. Increased expression of IL‐8 receptors after initiation of labor may indicate that IL‐8 receptors might have a role during parturition.
Infertile women with and without endometriosis: A case control study of luteal phase and other infertility conditions
Authors: Matorras Roberto , Rodríguez Fernando , Pérez Carlos , Pijoan Jose Ignacio , Neyro Jose Luis , Rodríguez‐escudero Francisco Javier 
Published: November 2007

Objective. To assess the relationship in infertile women between endometriosis and luteal phase defects and other infertility conditions.Setting. University Medical School.Design. Case‐control study.Patients. One hundred and seventy‐four infertile women with endometriosis and 174 infertile women without endometriosis, all of them studied by laparoscopy. The inclusion criteria were failure of six cycles of ovulation stimulation or abnormal preliminary study (abnormal pelvic physical, hysterosalpingographic or ultrasound findings).Results. The frequency of out‐of‐phase biopsies (16.1%vs 16.7%) as well as other endometrial abnormalities were similar in endometriosis associated infertility (EAI) and in non‐endometriosis infertility (NEI). Mean progesterone and prolactin levels, as well as the proportion of abnormal progesterone levels (37.4%vs 44.3%) and of hyperprolactinemia (12.9%vs 13.2%) were similar in EAI and NEI. The frequency of uterine myomas was similar in both groups. Sperm characteristics were not better in EAI than in NEI. Higher endometriosis stages were not associated with a higher frequency of the aforementioned conditions.Conclusion. Luteal phase defects, sperm abnormalities and myomas are no more common in EAI than in NEI or in advanced stages of endometriosis.
Infertility and subfertility in Norwegian women aged 40‐42 Prevalence and risk factors
Authors: Sundby Johanne , Schei Berit 
Published: November 2007

Background. There are few population estimates of the prevalence of infertility that also include some information about medical conditions and social classification of study objects. This is a study of 4034 out of a total of 5139 (78% of all invited) women in one county of Norway.Methods. All female inhabitants born 1950 to 1952 living in the county were invited to participate in a health screening. The screening comprised a clinical screening and two questionnaires; one about reproductive history and infertility.Results. This survey found permanent primary infertility in 2.6% of the women. Subfertility, as at least one year's delay of pregnancy, was reported by 7.7%. A history of different reproductive problems was associated with impaired fertility. Thirty‐two percent of primary infertile women had a history of PID, 13% had experienced amenorrhea and almost 40% reported premenstrual tension, compared with lower frequencies in women with normal fertility (11.0%, 3.3% and 29.4% respectively).Conclusions. Up to 10% of the female population may experience infertility at one stage in their reproductive career. Clinicians should pay special attention to women presenting any genital or reproductive disorder regarding risks for future fertility impairment.
Effects of thyroxine therapy on bone metabolism in postmenopausal women with hypothyroidism
Authors: Affinito Pietro , Sorrentino Claudia , Farace Maria Jussie , di Carlo Costantino , Moccia Gianfranco , Canciello Pasqualina , Palomba Stefano , Nappi Carmine 
Published: November 2007

Objective. To evaluate whether thyroid stimulating hormone‐suppressive thyroxine replacement therapy increases bone loss in postmenopausal women.Materials and method. The study had a cross‐sectional design. Fifty‐four postmenopausal women on long‐term treatment with thyroxine for primary hypothyroidism, who showed suppressed thyroid stimulating hormone levels were enrolled in our study. In these patients and in a control group of 54 healthy postmenopausal women we evaluated bone mineral density at distal radius and the main biochemical parameters of bone turnover. Student's t test, Wilcoxon signed rank‐test, Chi‐square test and the univariate linear regression in the statistical analysis of the data were employed.Results. Bone mineral density values, expressed as z‐scores, in the treated group were significantly decreased in comparison with the control group (p<0.01). We did not detect a significant relationship between different L‐thyroxine doses administered and bone mineral density z‐scores. On the contrary, an inverse correlation was detected between length of treatment and bone mineral density z‐scores. Treated patients showed a significantly higher concentration of serum alkaline phosphatase, osteocalcin, urinary calcium/creatinine and hydroxyproline/creatinine in comparison with the controls.Conclusions. Our study suggests that thyroxine replacement therapy in patients with suppressed thyroid stimulating hormone levels increases postmenopausal bone loss.
Prediction of genital prolapse after Burch colposuspension
Authors: Kjølhede Preben , Rydén Gunnar , Norén Bengt 
Published: November 2007

Objective. The aim of this prospective observational study was to investigate the gynecological and defecographic features in women with stress urinary incontinence operated with Burch colposuspension in order to analyze if the findings could predict subsequent development of genital prolapse.Subject. Twenty‐one women with urodynamically proven genuine stress urinary incontinence were consecutively operated with the Burch colposuspension during 1991‐1992. No concomitant prolapse repair surgery was performed.Methods. All were carefully examined in the lithotomy position at rest and with the Valsalva maneuver. The pelvic floor laxity was graded semiquantitatively. The defecography and the clinical examination were done preoperatively and repeated one year postoperatively.Results. The clinical examination revealed a significant progression of rectoceles (p=0.003) after the colposuspension. The colposuspension cured a significant number of cystoceles (p=0.035). Six women (29%) had subsequent corrective prolapse surgery median 2 years after the colposuspension.The defecographic measurements showed a significant increase of the recto‐vaginal distance (RVD) following the operation (p=0.020). At the postoperative measurement the group with subsequent prolapse surgery had a significantly larger RVD as compared to the group without further surgery (p=0.004). The kappa reliability test showed poor agreement between the defecographic and clinical assessment of the rectoceles.Conclusion. We failed to find any clinical or defecographic characteristic which could predict the development of surgery‐demanding genital prolapse following colposuspension. The colposuspension seemed to accelerate the deterioration of the pelvic floor. However, only a minority of the patients developed symptomatic genital prolapse demanding corrective surgery. We suggest that only women with symptomatic prolapse should be considered for concomitant corrective surgery at the time of the colposuspension.
DNA ploidy of ectopic pregnancy and first trimester spontaneous abortion investigated by flow cytometry
Authors: Erel Cemal Tamer , Kaleli Semih , Oral Engin , Engür AyE , Eren Tuncer , Calay Zerrin , Aydinli Kili 
Published: November 2007

Background. To compare the success rate of DNA flow cytometry in determining the DNA ploidy status in ectopic pregnancy and first trimester spontaneous abortion.Methods. Thirteen women with ectopic pregnancy (Group I) and 17 women with first trimester spontaneous abortion (Group II) were included into this study. DNA flow cytometric analysis was performed on all specimens. Aneuploidy was classified according to DNA index. The first trimester spontaneous abortions were also karyotyped after long‐term culture of chorionic villi. Student‐t test and Fisher's exact test were used in statistical comparisons.Results. DNA aneuploidy was found in five women with ectopic pregnancy (38.5%) versus in 12 women with first trimester spontaneous abortion (70.6%), and it was comparable. A triploidy and a tetraploidy were detected in group I. Six tubal ectopic pregnancies were unruptured at laparatomy and four of them had aneuploid DNA content.Conclusions. We believed that DNA flow cytometry was successful in determining the ploidy status of ectopic pregnancy and first trimester spontaneous abortion. In addition, it was interesting that ectopic pregnancies with aneuploid DNA content tended to be unruptured. However, this suggestion needs to be confirmed by further studies with larger numbers of cases.
Maternal renal artery blood flow velocimetry in normal and hypertensive pregnancies
Authors: Kublickas Marius , Lunell Nils‐Olov , Nisell Henry , Westgren Magnus 
Published: November 2007

Objective. To investigate the effect of normal pregnancy and hypertensive disorders of pregnancy on the maternal renal artery Doppler blood flow velocity indices.Methods. The patient material consisted of 30 normal pregnant women, 29 women with pregnancy induced hypertension, 43 women with preeclampsia and 22 pregnant women with chronic hypertension. Blood flow velocities in the segmental renal arteries from the right kidney were analysed by pulsed and color Doppler. The systolic/diastolic (s.d.) ratio, resistance index (RI) and pulsatility index (PI) were used for Doppler waveform analysis.Results. In all of the groups of hypertensive pregnant women renal artery Doppler indices were significantly lower compared to the normal pregnant women group. There was a significant negative relationship between renal artery PI and mean arterial pressure in the preeclampsia group and in the chronic hypertension group.Conclusion. The present results demonstrate that the mechanism of renal autoregulation in preeclampsia might be altered, leaving glomerulus unprotected from increased blood pressure. It seems that the concept of renal vasoconstriction in preeclampsia might be disputed and needs further investigation.
Nasal spray bromocriptine: Effects on serum prolactin in puerperal women
Authors: Cicinelli Ettore , Petruzzi Donatina , Ragno Gaetano , Schönauer Luca Maria , Ruccia Carmela , Matteo Giuseppina 
Published: November 2007

Background. The objective of this study was to investigate the effectiveness of a single nasal spray administration of 0.8 mg bromocriptine in reducing PRL serum levels.Methods. Eighteen physiologically hyperprolactemic women in the early days of puerperium were randomized to receive nasal bromocriptine or placebo; PRL serum levels were measured by RIA at 45, 30 and 15 minutes before the administration and after the following times: 15, 30, 45, 60, 120, 180, 240, 300, and 480 minutes.Results. After the administration of bromocriptine serum levels of PRL decreased rapidly; the reduction was statistically significant after 45 minutes. Four hours after the administration mean serum levels of PRL resulted in the normal range (<20 μg/1); at the eighth hour the PRL levels were still normal. No one patient complained of any local or systemic side‐effects.Conclusion. Nasal route seems to be an effective and probably safe administration route for bromocriptine.
Effect of post‐coital contraceptive methods on the endometrium and the menstrual cycle
Authors: Swahn Marja‐Liisa , Westlund Pär , Johannisson Elisabeth , Bygdeman Marc 
Published: November 2007

Study objective. To evaluate the effect of treatment with ethinylesteradiol‐levonorgestrel or danazol on ovarian function, gonadotrophin release and endometrial development during the time when a pregnancy may occur following unprotected intercourse.Methods. Women with regular menstrual cycles were followed during one control, one treatment and one follow‐up month. The women obtained either a combination of 0.5 mg levonorgestrel and 0.1 mg ethinylestradiol (Yuzpe regimen; n=16) or 600 mg danazol orally and repeated after 12 hours (n=16). The treatment was administered on either cycle day (cd) 12 or day LH+2. An endometrial biopsy was obtained once on cd LH+6 to +8 in the subjects treated on cd LH+2 both in control and treatment cycles, and morphometric analysis was performed. The concentrations of LH, pregnandiol (P2G), and estrone (E1G) glucuronide were followed daily in morning urine during control and treatment cycles.Results. Following treatment with the Yuzpe regimen on cd 12 the LH surge was either undetectable (three subjects), postponed to cd 16 to 22 (three subjects) or cd 38 to 39 (two subjects) with lower P2G and LH levels than in the control cycle. Following preovulatory treatment with danazol, no LH peak could be detected in four subjects and in the remaining four subjects the LH peak varied between cd 13 and cd 24. The mean area under the curve for LH was significantly lower, the levels of E1G were slightly higher and the P2G levels were unaffected in comparison with the control cycle. Neither of the two treatments administered on cd LH+2 affected the hormonal pattern and only a discreet effect on the development of the endometrium was seen after the EE/LNG treatment.Conclusion. The findings indicate that the contraceptive effect of postcoital treatment with EE/LNG and danazol is mainly due to an inhibition or delay of ovulation and insufficient corpus luteum function. The direct effect on the endometrium is limited, if any.
Cigarette Smoking and Psychiatric Morbidity in Women
Authors: Romans S. E. , McNoe B. M. , Herbison G. P. , Walton V. A. , Mullen P. E. 
Published: November 2007

A random community survey of psychiatric morbidity in adult New Zealand women, the Otago Women's Health Survey, investigated the association of cigarette smoking with mental health. Of the women interviewed, just over one quarter (26.1%) smoked, with one third of these smokers consuming more than 20 cigarettes per day. Demographic factors associated with smoking were younger age, lower socioeconomic status, poor education, caring for preschool children, dissatisfaction with female caring roles and financial strife. Psychiatric morbidity as measured by the short PSE was statistically associated with smoking. The unexpected finding reported here is a higher rate of recovery from their psychiatric morbidity amongst women who smoked. This result fits with previously reported data indicating that women use cigarette smoking to regulate mood and cope with the pressures of relentless child care in the context of strained financial resources. The profile of the woman who smokes differed substantially from that of the woman who drinks alcohol in a hazardous manner. Different preventive strategies are therefore required for these two risky behaviours.
The Concentration Camp Syndrome
Authors: Bower Herbert 
Published: November 2007

A psychiatric syndrome following overwhelming stress after an interval of more than thirty years is described in holocaust survivors who had claimed compensation for persecution between 1939 and 1945. Five nuclear symptom complexes emerge: depressive reactions; anxiety states; somatic complaints; subjective intellectual impairment; and contact abnormalities. Subjects who had experienced persecution during their childhood exhibited contact abnormalities of an aggressive type three times as often as survivors who had suffered an identical trauma as adults.