bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effectiveness of pharmacist-led medication reconciliation on medication errors at hospital discharge and healthcare utilization in the next 30 days: a pragmatic clinical trial
Authors: Jošt Maja , Kerec Kos Mojca , Kos Mitja , Knez Lea 
Published: March 2024

Transitions of care often lead to medication errors and unnecessary healthcare utilization. Medication reconciliation has been repeatedly shown to reduce this risk. However, the great majority of evidence is limited to the provision of medication reconciliation within clinical trials and countries with well-established clinical pharmacy. Thus, this pragmatic, prospective, controlled trial evaluated the effectiveness of routine pharmacist-led medication reconciliation compared to standard care on medication errors and unplanned healthcare utilization in adult general medical patients hospitalized in a teaching hospital in Slovenia. All patients hospitalized in a ward where medication reconciliation was integrated into routine clinical practice were included in the intervention group and received admission and discharge medication reconciliation, coupled with patient counselling. The control group consisted of randomly selected patients from the remaining medical wards. The primary study outcome was unplanned healthcare utilization within 30 days of discharge, and the secondary outcomes were clinically important medication errors at hospital discharge and serious unplanned healthcare utilization within 30 days of discharge. Overall, 414 patients (53.4% male, median 71 years) were included—225 in the intervention group and 189 in the control group. In the intervention group, the number of patients with clinically important medication errors at discharge was significantly lower (intervention vs control group: 9.3% vs 61.9%). Multiple logistic regression revealed that medication reconciliation reduced the likelihood of a clinically important medication error by 20-fold, while a higher number of medications on admission was associated with an increased likelihood. However, no significant differences were noted in any and serious unplanned healthcare utilization (intervention vs control group: 33.9% vs 27.8% and 20.3% vs 14.6%, respectively). The likelihood of serious healthcare utilization increased with the age of the patient, the number of medications on admission and being hospitalized for an acute medical condition. Our pragmatic trial confirmed that medication reconciliation, even when performed as part of routine clinical practice, led to a substantial reduction in the risk of clinically important medication errors at hospital discharge but not to a reduction in healthcare utilization. Medication reconciliation is a fundamental, albeit not sufficient, element to ensure patient safety after hospital discharge.Clinical Trial Registration:https://clinicaltrials.gov/search?id=NCT06207500, identifier NCT06207500
Simulating short-term light responses of photosynthesis and water use efficiency in sweet sorghum under varying temperature and CO2 conditions
Authors: Yang Xiao-Long , Ma Xiao-Fei , Ye Zi-Piao , Yang Long-Sheng , Shi Jun-Bo , Wang Xun , Zhou Bei-Bei , Wang Fu-Biao , Deng Zi-Fa 
Published: March 2024

Climate change, characterized by rising atmospheric CO2 levels and temperatures, poses significant challenges to global crop production. Sweet sorghum, a prominent C4 cereal extensively grown in arid areas, emerges as a promising candidate for sustainable bioenergy production. This study investigated the responses of photosynthesis and leaf-scale water use efficiency (WUE) to varying light intensity (I) in sweet sorghum under different temperature and CO2 conditions. Comparative analyses were conducted between the An-I, gs-I, Tr-I, WUEi-I, and WUEinst-I models proposed by Ye et al. and the widely utilized the non-rectangular hyperbolic (NRH) model for fitting light response curves. The Ye's models effectively replicated the light response curves of sweet sorghum, accurately capturing the diminishing intrinsic WUE (WUEi) and instantaneous WUE (WUEinst) trends with increasing I. The fitted maximum values of An, gs, Tr, WUEi, and WUEinst and their saturation light intensities closely matched observations, unlike the NRH model. Despite the NRH model demonstrating high R2 values for An-I, gs-I, and Tr-I modelling, it returned the maximum values significantly deviating from observed values and failed to generate saturation light intensities. It also inadequately represented WUE responses to I, overestimating WUE. Across different leaf temperatures, An, gs, and Tr of sweet sorghum displayed comparable light response patterns. Elevated temperatures increased maximum An, gs, and Tr but consistently declined maximum WUEi and WUEinst. However, WUEinst declined more sharply due to the disproportionate transpiration increase over carbon assimilation. Critically, sweet sorghum An saturated at current atmospheric CO2 levels, with no significant gains under 550 μmol mol−1. Instead, stomatal closure enhanced WUE under elevated CO2 by coordinated gs and Tr reductions rather than improved carbon assimilation. Nonetheless, this response diminished under simultaneously high temperature, suggesting intricate interplay between CO2 and temperature in modulating plant responses. These findings provide valuable insights into photosynthetic dynamics of sweet sorghum, aiding predictions of yield and optimization of cultivation practices. Moreover, our methodology serves as a valuable reference for evaluating leaf photosynthesis and WUE dynamics in diverse plant species.
A deep multi-task learning approach to identifying mummy berry infection sites, the disease stage, and severity
Authors: Qu Hongchun , Zheng Chaofang , Ji Hao , Huang Rui , Wei Dianwen , Annis Seanna , Drummond Francis 
Published: March 2024

IntroductionMummy berry is a serious disease that may result in up to 70 percent of yield loss for lowbush blueberries. Practical mummy berry disease detection, stage classification and severity estimation remain great challenges for computer vision-based approaches because images taken in lowbush blueberry fields are usually a mixture of different plant parts (leaves, bud, flowers and fruits) with a very complex background. Specifically, typical problems hindering this effort included data scarcity due to high manual labelling cost, tiny and low contrast disease features interfered and occluded by healthy plant parts, and over-complicated deep neural networks which made deployment of a predictive system difficult.MethodsUsing real and raw blueberry field images, this research proposed a deep multi-task learning (MTL) approach to simultaneously accomplish three disease detection tasks: identification of infection sites, classification of disease stage, and severity estimation. By further incorporating novel superimposed attention mechanism modules and grouped convolutions to the deep neural network, enabled disease feature extraction from both channel and spatial perspectives, achieving better detection performance in open and complex environments, while having lower computational cost and faster convergence rate.ResultsExperimental results demonstrated that our approach achieved higher detection efficiency compared with the state-of-the-art deep learning models in terms of detection accuracy, while having three main advantages: 1) field images mixed with various types of lowbush blueberry plant organs under a complex background can be used for disease detection; 2) parameter sharing among different tasks greatly reduced the size of training samples and saved 60% training time than when the three tasks (data preparation, model development and exploration) were trained separately; and 3) only one-sixth of the network parameter size (23.98M vs. 138.36M) and one-fifteenth of the computational cost (1.13G vs. 15.48G FLOPs) were used when compared with the most popular Convolutional Neural Network VGG16.DiscussionThese features make our solution very promising for future mobile deployment such as a drone carried task unit for real-time field surveillance. As an automatic approach to fast disease diagnosis, it can be a useful technical tool to provide growers real time disease information that can prevent further disease transmission and more severe effects on yield due to fruit mummification.
Geographical patterns and environmental influencing factors of variations in Asterothamnus centraliasiaticus seed traits on Qinghai-Tibetan plateau
Authors: Li ZhengSheng , Ma YuShou , Liu Ying , Wang YanLong , Wang XinYou 
Published: March 2024

IntroductionSeed traits related to recruitment directly affect plant fitness and persistence. Understanding the key patterns and influencing factors of seed trait variations is conducive to assessing plant colonization and habitat selection. However, the variation patterns of the critical seed traits of shrub species are usually underrepresented and disregarded despite their vital role in alpine desert ecosystems.MethodsThis study gathered seeds from 21 Asterothamnus centraliasiaticus populations across the Qinghai-Tibetan Plateau, analyzing geographical patterns of seed traits to identify external environmental influences. Additionally, it explored how seed morphology and nutrients affect germination stress tolerance, elucidating direct and indirect factors shaping seed trait variations.ResultsThe results present substantial intraspecific variations in the seed traits of A. centraliasiaticus. Seed traits except seed length-to-width ratio (LWR) all vary significantly with geographic gradients. In addition, the direct and indirect effects of climatic variables and soil nutrients on seed traits were verified in this study. Climate mainly influences seed nutrients, and soil nutrients significantly affect seed morphology and seed nutrients. Furthermore, climate directly impacts seed germination drought tolerance index (GDTI) and germination saline-alkali tolerance index (GSTI). Seed germination cold tolerance index (GCTI) is influenced by climate and soil nutrients (mostly SOC). GDTI and GSTI are prominently influenced by seed morphology (largely the seed thousand-grain weight (TGW)), and GCTI is evidently affected by seed nutrients (mainly the content of soluble protein (CSP)).DiscussionThe findings of this study amply explain seed trait variation patterns of shrubs in alpine desert ecosystems, possessing significant importance for understanding the mechanism of shrub adaptation to alpine desert ecosystems, predicting the outcomes of environmental change, and informing conservation efforts. This study can be a valuable reference for managing alpine desert ecosystems on the Qinghai-Tibetan Plateau.
Increased sensitivity for negative emotional images in individuals with problematic pornography use
Authors: Qu Shuangyi , Li Ruiyu , Wang Jianfeng 
Published: March 2024

BackgroundDespite the frequent comorbidity of affective and addictive disorders, the significance of affective dysregulation in problematic pornography use (PPU) is commonly disregarded. The objective of this study is to investigate whether individuals with PPU demonstrate increased sensitivity to negative emotional stimuli in comparison to healthy controls (HCs).MethodsElectrophysiological responses were captured via event-related potentials (ERPs) from 27 individuals with PPU and 29 HCs. They completed an oddball task involving the presentation of deviant stimuli in the form of highly negative (HN), moderately negative (MN), and neutral images, with a standard stimulus being a neutral kettle image. To evaluate participants' subjective feelings of valence and arousal, the Self-Assessment Manikin (SAM) was employed.ResultsRegarding subjective evaluations, individuals with PPU indicated diminished valence ratings for HN images as opposed to HCs. Concerning electrophysiological assessments, those with PPU manifested elevated N2 amplitudes in response to both HN and MN images when contrasted against neutral images. Additionally, PPU participants displayed an intensified P3 response to HN images in contrast to MN images, a distinction not evident within the HCs.DiscussionThese outcomes suggest that individuals with PPU exhibited heightened reactivity toward negative stimuli. This increased sensitivity to negative cues could potentially play a role in the propensity of PPU individuals to resort to pornography as a coping mechanism for managing stress regulation.
Parents’ perceptions of the impact of the novel coronavirus (COVID-19) on the eating behaviors and routines of children with autism spectrum disorders (ASD)
Authors: Alharbi Mudi H. 
Published: March 2024

BackgroundRestricted interests and repetitive behavior are characteristics of autism spectrum disorder (ASD). The likelihood that persons with ASD will respond adversely to unfamiliar situations is great. The novel coronavirus outbreak has resulted in disruptions to all aspects of routine and behavior. Hence, this study proposed to investigate the impact of the outbreak on the eating behavior and routines of children with ASD in Saudi Arabia through the perceptions of their parents.MethodA cross-sectional study with a quantitative approach was utilized to obtain data from 150 parents of children with ASD aged ≤18 years in Saudi Arabia. The data collected included demographic data of the parents, the ASD status of the family, impact of COVID-19 to the family, eating behavior of the children with ASD, and daily routines of the children with ASD. Moreover, parents were able to provide comments regarding their children’s eating behavior or daily routines.ResultsThe study found that changes in the eating behavior of children with ASD were found to differ significantly (p&lt;0.05) based on the number of children with ASD, the age of the children with ASD, the gender of the children with ASD, and the severity of their ASD symptoms. Moreover, changes to dinner-time routines were found to differ significantly (p&lt;0.05) based on the age of the children with ASD. Also, changes to morning routines were found to differ significantly (p&lt;0.05) based on the age of the children with ASD, their gender, and the severity of their ASD symptoms. Additionally, impact of COVID-19 to the family had a significant impact to eating behavior and daily routines of the children with ASD.ConclusionThis study found that the eating behavior and daily routines of children with ASD in Saudi Arabia have been considerably worsened and changed. The study recommends the collaboration of multidisciplinary teams and parents to modify or design interventions that help to change their eating behavior and routine can be implemented in the home. It also recommends the provision of virtual helplines to aid parents of children with ASD in such cases.
Evaluation of China’s long-term care insurance policies
Authors: Li Qiang , Chen Yiwen , Zhang Yongmei , Liu Xue 
Published: March 2024

IntroductionIn response to the increasing demand for long-term care services for older people, the Chinese government has launched a pilot program for long-term care insurance (LTCI) since 2016. The objective of this study is to evaluate the performance and effectiveness of this program in China and provide recommendations for the future development and expansion of the LTCI system.MethodsWe developed a comprehensive evaluation framework to assess these LTCI policies implemented in all 49 pilot cities in China.ResultsBased on our evaluation, the average assessment score for the LTCI program across all pilot cities was 71.8 points, with scores ranging from 57.5 to 92.5 points in these cities. Furthermore, most of the pilot cities achieved higher scores in the fact-based assessment compared to the value-based assessment.DiscussionThe results suggested that the overall pilot effect regarding LTCI was favorable, but there were significant regional disparities. Moreover, in most of pilot cities, current LTCI policies were designed to alleviate both the financial burden and the burden of caring for people with disabilities that families faced. However, some challenges still remained, such as the lack of community and home-based care services, the need to expand the coverage of insurance, and the importance of diversifying funding sources.
The relationship between self-reported poor mental health and complete tooth loss among the US adult population in 2019
Authors: Powell Tasha , Taylor Heather 
Published: March 2024

ObjectiveVery little is known about the association between poor mental health and poor oral health outcomes in the United Sates. This study investigated the prevalence of complete tooth loss among those with and without perceived poor mental health in a nationally representative sample of noninstitutionalized U.S. adults.MethodsUsing a cross-sectional study design, we analyzed the 2019 Medical Expenditures Panel Survey to determine the unweighted and weighted prevalence of complete tooth loss among adults. Chi-squared and multivariate logit regression with marginal effects were used to measure the association between complete tooth loss and perceived poor mental health, controlling for respondent characteristics.ResultsThe prevalence of adults (ages 18 and older) experiencing complete tooth loss was 6% (95% CI: 5.6–6.4). Individuals who have perceived poor mental health were 1.90 percentage points (pps) more likely to report missing all their natural teeth (P = 0.006: 95% CI: 0.5–3.3). Other relevant predictors of complete tooth loss included current smoking status (5.9 pps; 95% CI: 4.5 to 7.2) and secondary education (−6.4 pps (95% CI: −7.0 to −4.8).ConclusionsOverall, self-reported poor mental health was found to be associated with a greater likelihood of reporting complete tooth loss. Findings from this study underscore the need for greater integration of care delivery between behavioral health specialists and dental providers.
Phycoremediation Potential of Salt-Tolerant Microalgal Species: Motion, Metabolic Characteristics, and Their Application for Saline–Alkali Soil Improvement in Eco-Farms
Authors: Chen Huiying , Yu Siteng , Yu Ze , Ma Meng , Liu Mingyan , Pei Haiyan 
Published: March 2024

Microalgae have great potential for remediating salt-affected soil. In this study, the microalgae species Coelastrella sp. SDEC-28, Dunaliella salina SDEC-36, and Spirulina subsalsa FACHB-351 were investigated for their potential to rehabilitate salt-affected soils. Nylon screens with optimal aperture sizes and layer numbers were identified to efficiently intercept and harvest biomass, suggesting a correlation between underflow capability and the tough cell walls, strong motility, and intertwining characteristics of the algae. Our investigations proved the feasibility of incorporating monosodium glutamate residue (MSGR) into soil extracts at dilution ratios of 1/200, 1/2000, and 1/500 to serve as the optimal medium for the three microalgae species, respectively. After one growth period of these three species, the electrical conductivities of the media decreased by 0.21, 1.18, and 1.78 mS/cm, respectively, and the pH remained stable at 7.7, 8.6, and 8.4. The hypotheses that microalgae can remediate soil and return profits have been verified through theoretical calculations, demonstrating the potential of employing specific microalgal strains to enhance soil conditions in eco-farms, thereby broadening the range of crops that can be cultivated, including those that are intolerant to saline–alkali environments.
MANIFESTASI KEPERCAYAANNYA MASYARAKAT JEPANG TERHADAP DEWA EBISU
Authors: Heryana Chrisna Yuda Tama , Ali Mohammad 
Published: March 2024

Selain terkenal dengan kemajuan teknologinya, Negara Jepang terkenal juga sebagai negri para dewa dikarenakan terdapat banyak mitologi tentang dewa di Jepang dan salah satu dewa yang terkenal adalah dewa Ebisu. Ebisu adalah dewa keberuntungan yang saat ini masih dipercayai keberadaan nya oleh masyarakat Jepang. Didasari dengan antusiasme masyarakat Jepang terhadap dewa Ebisu, penulis hendak melakukan penelitian dengan tujuan untuk mengetahui manifestasi kepercayaanya masyarakat Jepang kepada dewa Ebisu dan perwujudan dewa Ebisu pada budaya pop Jepang. Adapun metode yang digunakan oleh penulis pada penelitian ini adalah metode kualitatif dengan pendekatan deskriptif Hasil dari penelitian ini ialah ditemukannya beberapa manifesstasi dari kepercayaannya masyarakat Jepang kepada dewa Ebisu yaitu berdoa,berhala dan Matsuri. Manifestasi yang pertama adalah berdoa kepada dewa Ebisu, ini merupakan manifestasi yang paling sering dilakukan masyarakat Jepang dikarenakan ini merupakan manifestasi yang dirasa paling praktis. Kedua yaitu Berhala, masyarakat Jepang mempercayai kerbekahan dari dewa Ebisu dan perlindungan nya dapat mereka dapatkan juga dalam wujud berbentuk sebuah benda. Terakhir adalah Matsuri, Kegiatan Matsuri ini pada hakikatnya merupakan suatu kegiatan untuk mengundang Dewa atau menyambut kehadiran Dewa, dengan menyajikan segala sajian yang ada dan dengan menunjukkan sikap mengabdikan diri pada dewa agar mendapatkan petunjuk dan berkah. Adapun perwujudan dari dewa Ebisu pada budaya popular Jepang yaitu berupa karakter yang memiliki dasar dewa Ebisu. Penggambaran wujud dan sifat Ebisu pada budaya popular telah mengalami perubahan apabila dibandingkan dengan wujud dan sifat pada dari mitologi rakyat Jepang. Adanya perubahan penggambaran ini juga dirasa berfungsi sebagai bentuk adaptasi zaman.
Kata Kunci: Kepercayaan, Perwujudan, Mitologi, Ebisu
PERANCANGAN VIRTUAL YOUTUBER SEBAGAI MEDIA PEMBELAJARAN KOSAKATA BAHASA JEPANG TINGKAT PEMULA
Authors: Ponsen Keygi Nisatazkiyah Floresti , Setiana Soni Mulyawan 
Published: March 2024

Media pembelajaran adalah alat untuk mendukung proses pembelajaran agar dapat berjalan dengan baik. Pada pembelajaran Bahasa Jepang, ditemukan masalah di mana siswa kesulitan untuk menghafal kosakata yang merupakan salah satu poin penting dalam mempelajari bahasa. Penelitian ini bertujuan untuk mendeskripsikan proses pembuatan media pembelajaran menggunakan Virtual Youtuber (Vtuber) yang merupakan online entertainer yang tampil sebagai virtual avatar berbentuk 2 dimensi atau 3 dimensi dengan memanfaatkan teknologi motion capture. Media pembelajaran ini menggunakan model ADDIE untuk pengembangan dan Live2D serta IoLive sebagai software untuk menganimasikan model Vtuber. Hasilnya adalah video-video pembelajaran kosakata bahasa Jepang yang dapat diakses melalui kanal Youtube. Media pembelajaran ini cocok untuk pembelajar bahasa Jepang tingkat pemula.
Kata kunci: Virtual Youtuber, Live2D, media pembelajaran, kosakata bahasa Jepang