bluuebunny/crossref_metadata_2025_split huggingface dataset:
Dissolution Mechanism for Dendrite‐Free Aqueous Zinc‐Ions Batteries
Authors: Li Zhongheng , Shu Zheng , Shen Zhaoxi , Liu Yu , Ji Yu , Luo Lei , Li Rui , Cai Yongqing , Ian Hou , Xie Junpeng , Hong Guo 
Published: April 2024

AbstractThe commercialization of aqueous Zn‐ion batteries (AZIBs) for power‐grid energy storage systems is hindered by the safety concerns arising from the Zn dendrite growth. The primary approach in addressing this issue is to induce planar depositions. However, modulating the Zn dissolution process which directly reshapes surface morphology and reserves growth sites has long been overlooked. Herein, by utilizing ester compounds as an illustration, it is revealed that engineering the dissolution energy barrier is a pivotal factor in promoting homogeneous Zn dissolution. Ester adsorbents effectively redistribute charge densities at the electrode–electrolyte interface due to the presence of zincophilic ester functional group and conductive π‐conjugation structure. This effect eventually facilitates Zn dissolution across the surface, transforming the potholed and defective dissolution morphology into a smooth and consistent form. Thus, enhanced cycling stability can be achieved in both half‐cells and full‐cells, offering an extensive lifespan of thousands of hours for the dissolution and deposition cycles. This work provides a principle for the selection of Zn dissolution improvers to suppress Zn metal dendrite growth by regulating Zn dissolution behavior.
Innovative approach to predict soil moisture using the backpropagation‐Elman neural network
Authors: Zhang Ao Yang , Wei Na , Xue Jin , Qiao Yi , Hu Haiyu , Mou Lei , Wang Xingwei 
Published: April 2024

AbstractAccurate moisture prediction aids in taking early preventive measures to minimize damage caused by severe storms, droughts, and floods. The study collected 24 types of statistical data from the Xilingol Grassland, Inner Mongolia, spanning from 2011 to 2021. By integrating Elman, backpropagation (BP), and soil moisture prediction model (Elman‐BP) neural networks, soil moisture to 2 m was predicted. The soil moisture mechanism model analysis revealed that soil moisture is related to water supply rather than directly correlated with time. Based on these findings, a two‐stage soil moisture prediction model was established. In the first stage, the Elman neural network model predicted future precipitation data based on observed values. In the second stage, soil moisture was predicted using a BP neural network model based on predicted precipitation data. Comparing the mean squared errors of training and prediction data across the three models revealed that the Elman‐BP neural network had superior predictive accuracy. The maximum relative errors for the trained Elman neural network, BP neural network, and Elman‐BP model were 31.35%, 20.98%, and 3.94%. Overall, results showed a link between soil moisture and water supply and that soil moisture decreased with increasing temperatures. Soil moisture at 10‐ and 40‐cm depths was increased with increasing rainfall. Furthermore, a delay exists between the 40‐ and 100‐cm soil depths. Moreover, soil moisture stability increased with depth.
Induction vacuum swing adsorption over magnetic sorbent monoliths and extrudates for ethylene/ethane separation
Authors: Baamran Khaled , Shareef Usman , Rezaei Fateme 
Published: April 2024

AbstractElectrification of adsorption processes is emerging as an adaptable solution for future gas separations. This study develops magnetic sorbent structures for use in induction vacuum swing adsorption (IVSA) process specifically designed for olefin/paraffin separation. Two sorbents, namely Fe3O4/ZIF‐7 (ethane‐selective) and Fe3O4/13X (ethylene‐selective) were developed and formulated into extrudates (Fe20/ZIF‐7‐P) and monoliths (Fe20/13X‐M), and tested under different regeneration scenarios, including simultaneous and subsequent induction‐evacuation, induction only, and evacuation only. The dynamic adsorption results demonstrated that regeneration under subsequent induction‐evacuation improves desorption rate and capability. Under this regeneration scenario, Fe20/ZIF‐7‐P achieved an ethane desorption rate of 0.24 mmol/g.min, representing a remarkable 37.5% enhancement over the induction‐only scenario. Similarly, Fe20/13X‐M exhibited an ethylene desorption rate of 0.35 mmol/g.min, indicative of a 34.2% enhancement. Moreover, the IVSA cyclic runs highlighted the excellent regeneration capability and stability of both Fe20/ZIF‐7‐P and Fe20/13X‐M with Fe20/13X‐M exhibiting ethylene purity, recovery, and productivity of 99.4%, 99.6%, and 39.9 mol/kg.h, respectively. Overall, these findings underscore the potential of the hybrid induction/vacuum process as an effective technique for achieving efficient regeneration of sorbents in olefin/paraffin separation.
Gas‐Induced Electrical and Magnetic Modulation of Two‐Dimensional Conductive Metal–Organic Framework
Authors: Meng Zheng , Stolz Robert M. , De Moraes Lygia Silva , Jones Christopher G. , Eagleton Aileen M. , Nelson Hosea M. , Mirica Katherine A. 
Published: April 2024

AbstractControlled modulation of electronic and magnetic properties in stimuli‐responsive materials provides valuable insights for the design of magnetoelectric or multiferroic devices. This paper demonstrates the modulation of electrical and magnetic properties of a semiconductive, paramagnetic metal−organic framework (MOF) Cu3(C6O6)2 with small gaseous molecules, NH3, H2S, and NO. This study merges chemiresistive and magnetic tests to reveal that the MOF undergoes simultaneous changes in electrical conductance and magnetization that are uniquely modulated by each gas. The features of response, including direction, magnitude, and kinetics, are modulated by the physicochemical properties of the gaseous molecules. This study advances the design of multifunctional materials capable of undergoing simultaneous changes in electrical and magnetic properties in response to chemical stimuli.
Heteroatom Substitution Strategy Modulates Thermodynamics Towards Chemically Recyclable Polyesters and Monomeric Unit Sequence by Temperature Switching
Authors: Zhang Da , Wang Xin , Zhang Zhengbiao , Hadjichristidis Nikos 
Published: April 2024

AbstractIn this paper, we proposed a heteroatom substitution strategy (HSS) in the δ‐valerolactone (VL) system to modulate thermodynamics toward chemically recyclable polyesters. Three VL‐based monomers containing different heteroatoms (M1 (N), M2 (S), and M3 (O)), instead of C‐5 carbon, were designed and synthesized to verify our proposed HSS. All three monomers undergo organocatalytic living/controlled ROP and controllable depolymerization. Impressively, the resulting P(M1) achieved over 99 % monomer recovery under both mild solution depolymerization and high vacuum pyrolysis conditions without any side reactions, and the recycled monomers can be polymerized again forming new polymers. The systematic study of the relationship between heteroatom substitution and recyclability shows that introducing heteroatoms does change the thermodynamics of the monomers (ΔHpo, ΔSpo and Tc values), thereby adjusting the polymerizability and depolymerizability. DFT calculations found that the introduction of heteroatoms adjusts the ring strain by changing the angular strain of the monomers, and the order of their angular strain (M2>M1>M3) is consistent with the order of the experimentally obtained enthalpy change. Notably, the one‐pot/one‐step copolymerization of two of each of the three monomers enables the synthesis of sequence‐controlled copolymers from gradient to random to block structures, by simply switching the copolymerization temperature.
Do corporate sustainability practices mitigate earnings management? The moderating role of firm size
Authors: Rahman Haseeb Ur , Zahid Muhammad , Khan Parvez Alam , Al‐Faryan Mamdouh Abdulaziz Saleh , Hussainey Khaled 
Published: April 2024

AbstractThe majority of the prior empirical literature that inquired about the direct role of corporate sustainability practices (CSP) as a composite construct in mitigating earnings management (EM) has produced equivocal outcomes. Therefore, this study examines the role of CSP not only as a combined construct but also as its three separate dimensions—social, economic, and environmental sustainability in restricting EM directly and with the distinct moderation of firm size that has rarely been probed in the past. Using the data of 255 Pakistani companies from 2018 to 2022, the estimations of ordinary least squares with panel‐corrected standard errors revealed that CSP and its separate dimensions significantly control accruals‐based earnings management, and all these relationships are further amplified by the moderation of firm size. However, neither CSP nor any of its dimensions, either directly or with the moderation of firm size, have a significant role in reducing real‐based earnings management. The additional analysis also validated these findings but only for large companies rather than small companies after splitting the sample based on the firm's size. The findings endorse the stakeholder theory and ethical perspective but oppose managerial opportunism in Pakistan. Besides enriching the existing body of knowledge, this research also offers several important implications for the theory, methodology, practice, and policy.
Pursuing dynamics of minimal residual leukemic subclones in relapsed and refractory acute myeloid leukemia during conventional therapy
Authors: Kim Dongchan , Kim Sheehyun , Song Hyojin , Gwak Daehyeon , Min Suji , Byun Ja Min , Koh Youngil , Hong Junshik , Yoon Sung‐Soo , Yun Hongseok , Shin Dong‐Yeop 
Published: April 2024

AbstractBackgroundAcute myeloid leukemia (AML) is characterized by clonal heterogeneity, leading to frequent relapses and drug resistance despite intensive clinical therapy. Although AML's clonal architecture has been addressed in many studies, practical monitoring of dynamic changes in those subclones during relapse and treatment is still understudied.MethodFifteen longitudinal bone marrow (BM) samples were collected from three relapsed and refractory (R/R) AML patients. Using droplet digital polymerase chain reaction (ddPCR), the frequencies of patient's leukemic variants were assessed in seven cell populations that were isolated from each BM sample based on cellular phenotypes. By quantifying mutant clones at the diagnosis, remission, and relapse stages, the distribution of AML subclones was sequentially monitored.ResultsMinimal residual (MR) leukemic subclones exhibit heterogeneous distribution among BM cell populations, including mature leukocyte populations. During AML progression, these subclones undergo active phenotypic transitions and repopulate into distinct cell population regardless of normal hematopoiesis hierarchic order. Of these, MR subclones in progenitor populations of patient BM predominantly carry MR leukemic properties, leading to more robust expansion and stubborn persistence than those in mature populations. Moreover, a minor subset of MR leukemic subclones could be sustained at an extremely low frequency without clonal expansion during relapse.ConclusionsIn this study, we observed treatment persistent MR leukemic subclones and their phenotypic changes during the treatment process of R/R AML patients. This underscores the importance of preemptive inhibition of clonal promiscuity in R/R AML, proposing a practical method for monitoring AML MR subclones.
An Analysis of Calendaric Aging over 5 Years of Ni‐Rich 18650‐Cells with Si/C Anodes
Authors: Frie Fabian , Ditler Heinrich , Klick Sebastian , Stahl Gereon , Rahe Christiane , Ghaddar Tala , Sauer Dirk Uwe 
Published: April 2024

AbstractCalendaric lifetime testing of lithium‐ion cells is time‐consuming and resource‐intensive. As Dubarry et al.[1] state, testing is often limited to a few aging conditions. This paper presents the results of a long‐term aging study on lithium‐ion cells with a nickel‐rich NCA cathode and a graphite‐silicon anode. 69 cells were stored at 5 different voltages and under 4 different temperatures for 5 years. Regular reference performance tests (RPT) provide insights for State of Health (SoH) calculation and further analysis through differential voltage analysis. The results are verified against post‐mortem analyses. The long aging period enables accurate determination of aging rates. Our results demonstrate that the storage voltage level strongly influences the degradation rate, with temperature playing a minor role. The identified aging effects include loss of active material on the cathode side and loss of lithium inventory. Initial degradation follows a
‐trajectory but is caused by overhang effects. The long‐term aging is rather linear.
Extended Reichardt's Dye–Synthesis and Solvatochromic Properties
Authors: Franzese Stephen , Saker Neto Nicolau , Wong Wallace W. H. 
Published: April 2024

AbstractThree new pyridinium‐phenolate dyes based on the benchmark solvatochromic dye Betaine 30 were synthesised. The dyes contained phenylene spacers between the donor and acceptor groups. Their UV‐Vis absorption spectra were measured, with the dyes showing strong negative solvatochromic behaviour comparable to that of Betaine 30. These results stood in contrast to the behaviour of the π‐extended dye Betaine 21, originally reported in 1963. This dye was synthesised and found to be significantly more solvatochromic than previously reported but prone to degrade. All π‐extended dyes synthesised were found to be unstable in certain solvents. Although the increased distance between donor and acceptor did not enhance solvatochromism to the extent predicted, it was still determined that the reduced planarity caused by a phenylene spacer is not as detrimental as believed.
Nonlinear oscillations of dust‐acoustic waves in non‐Maxwellian dusty plasma under the gravitational force effect
Authors: Fermous Rachid , Benzekka Moufida , Amour Rabia , Mebrek Rima 
Published: April 2024

AbstractIn this paper, the role of dust grain's gravitational force on the nonlinear dust‐acoustic oscillations in non‐Maxwellian dusty plasma is analyzed. It is shown that increasing the number of non‐thermal ions causes the diminution of the electrostatic potential's amplitude and a reduction in the number of oscillations introduced by the gravitational force. We have also found that reducing the size of the dust grain induces qualitatively the same effects as an increase in the number of non‐thermal ions and when the gravitational force is considered, the electric charge exhibits oscillatory profile and becomes less negative far away from the origin. This result may be interesting in the study of astrophysical plasmas where the electromagnetic force is smaller than the gravitational one such as in the Halley Comet.
Proinflammatory polarization strongly reduces human macrophage in vitro phagocytosis of tumor cells in response to CD47 blockade
Authors: Antonsen Kristian W. , Jensen Anne G. , Carstensen Mikkel , Nejsum Lene N. , Sorensen Boe S. , Etzerodt Anders , Moestrup Søren K. , Møller Holger J. 
Published: April 2024

AbstractAntibody‐based CD47 blockade aims to activate macrophage phagocytosis of tumor cells. However, macrophages possess a high degree of phenotype heterogeneity that likely influences phagocytic capacity. In murine models, proinflammatory (M1) activation increases macrophage phagocytosis of tumor cells, but in human models, results have been conflicting. Here, we investigated the effects of proinflammatory polarization on the phagocytic response of human monocyte‐derived macrophages in an in vitro model. Using both flow cytometry‐based and fluorescence live‐cell imaging‐based phagocytosis assays, we observed that mouse monoclonal anti‐CD47 antibody (B6H12) induced monocyte‐derived macrophage phagocytosis of cancer cells in vitro. Proinflammatory (M1) macrophage polarization with IFN‐γ+LPS resulted in a severe reduction in phagocytic response to CD47 blockade. This reduction coincided with increased expression of the antiphagocytic membrane proteins LILRB1 and Siglec‐10 but was not rescued by combination blockade of the corresponding ligands. However, matrix metalloproteinase inhibitors (TAPI‐0 or GM6001) partly restored response to CD47 blockade in a dose‐dependent manner. In summary, these data suggest that proinflammatory (M1) activation reduces phagocytic response to CD47 blockade in human monocyte‐derived macrophages.
A systematic vector autoregressive framework for modeling and forecasting mortality
Authors: Li Jackie , Liu Jia , Butt Adam 
Published: April 2024

AbstractRecently, there is a new stream of mortality forecasting research using the vector autoregressive model with different sparse model specifications. They have been shown to be able to overcome some of the limitations of the more traditional factor models such as the Lee–Carter model. In this paper, we propose a more generalized systematic vector autoregressive framework for modeling and forecasting mortality. Under this framework, we progressively increase the sophistication of the diagonal parameters in the autoregressive matrix and formulate a range of model structures in a systematic fashion. They offer much flexibility for capturing the mortality patterns of different populations. The resulting models produce age coherent forecasts, and their parameters are reasonably interpretable for modelers, demographers, and industry practitioners. Using the mortality data of Australia, Japan, New Zealand, and Taiwan, we demonstrate that the proposed approach generates appropriate forecasts of mortality rates and life expectancies and produces very good performance in the fitting and out‐of‐sample analysis.
Near‐Infrared Triggered Biodegradable Microneedle Patch for Controlled Macromolecule Drug Release
Authors: Cheng Yifan , Yang Junzhu , Han Sanyang , Lu Yuan 
Published: April 2024

AbstractTransdermal drug delivery of macromolecule drugs attracts significant attention due to the advantage of convenience and biocompatibility. However, the practical usage of it is limited by the low delivery efficiency and poor drug absorption. To develop an efficient, safe, and controllable transdermal delivery method, the near‐infrared (NIR) triggered calcium sulfate and gelatin biodegradable composite microneedle (MN) patches are developed. The MN patches are fabricated by polydimethylsiloxane (PDMS) molds, and the structure data can be adjusted by changing the molds. Such an MN patch can release both macro and micro molecule drugs. After loading with photothermal converter IR780, which can transfer energy of light to heat, the release of macromolecule drugs in MNs can be controlled by applying NIR irradiation. The control effect can be enhanced by spraying 1‐tetradecanol (TD) coating and optimizing the ratio (weight) of gelatin and calcium sulfate to 2:6. Besides, the MN patch can deliver drugs through the skin barrier, and the process can be controlled by NIR. Moreover, the insulin‐loaded MN patch exhibits some therapeutic effects on healthy mice. This work suggests that biodegradable MNs can achieve controllable drug delivery and potentially be applied in individual treatment via transdermal ingestion.
Anti‐ROS and NIR‐II‐Responsive Hyaluronic Acid Microneedle Loaded With Baicalin Nanoparticles for Treatment of Psoriasis
Authors: Xia Chuanlan , Fu Xinwei , Wang Qi , Chen Xinyue , Chen Jiucun , Kang Yuejun , Wang Bin 
Published: April 2024

AbstractIn this work, a natural medicine, baicalin, is designed for the treatment of psoriasis with the aid of hyaluronic acid (HA)‐based MNs patches. This is also to improve the solubility of baicalin and increase its residence time in infected part, which is made into nanoparticles by complexation with humic acid and Eu2+. The baicalin nanoparticles loaded‐MNs exhibit satisfactory rigidity, minimum injury, and controlled drug delivery. The anti‐reactive oxygen species (anti‐ROS) and anti‐inflammatory action are verified by the effective scavenging oxygen and nitrogen radicals. In addition, the loading of baicalin nanoparticles brings remarkable photothermic effect to the MNs, enabling the device to release a controlled drug under near‐infrared region II (NIR‐II) laser irradiation. With the aid of NIR‐II laser, the baicalin‐mediated treatment of psoriasis is significantly improved by expediting radical scavenging and suppressing inflammation. The design of baicalin MNs provides a new idea for the treatment of chronic disease.
Metabolic fingerprinting by nuclear magnetic resonance of hepatocellular carcinoma cells during p53 reactivation‐induced senescence
Authors: Knopf Philipp , Pacheco‐Torres Jesus , Zizmare Laimdota , Mori Noriko , Wildes Flonne , Zhou Benyuan , Krishnamachary Balaji , Mironchik Yelena , Kneilling Manfred , Trautwein Christoph , Pichler Bernd J. , Bhujwalla Zaver M. 
Published: April 2024

AbstractCellular senescence is characterized by stable cell cycle arrest. Senescent cells exhibit a senescence‐associated secretory phenotype that can promote tumor progression. The aim of our study was to identify specific nuclear magnetic resonance (NMR) spectroscopy‐based markers of cancer cell senescence. For metabolic studies, we employed murine liver carcinoma Harvey Rat Sarcoma Virus (H‐Ras) cells, in which reactivation of p53 expression induces senescence. Senescent and nonsenescent cell extracts were subjected to high‐resolution proton (1H)‐NMR spectroscopy‐based metabolomics, and dynamic metabolic changes during senescence were analyzed using a magnetic resonance spectroscopy (MRS)‐compatible cell perfusion system. Additionally, the ability of intact senescent cells to degrade the extracellular matrix (ECM) was quantified in the cell perfusion system. Analysis of senescent H‐Ras cell extracts revealed elevated sn‐glycero‐3‐phosphocholine, myoinositol, taurine, and creatine levels, with decreases in glycine, o‐phosphocholine, threonine, and valine. These metabolic findings were accompanied by a greater degradation index of the ECM in senescent H‐Ras cells than in control H‐Ras cells. MRS studies with the cell perfusion system revealed elevated creatine levels in senescent cells on Day 4, confirming the 1H‐NMR results. These senescence‐associated changes in metabolism and ECM degradation strongly impact growth and redox metabolism and reveal potential MRS signals for detecting senescent cancer cells in vivo.