bluuebunny/crossref_metadata_2025_split huggingface dataset:
Ruthenium‐Indenylidene Complexes: Scope in Cross‐Metathesis Transformations
Authors: Boeda Fabien , Bantreil Xavier , Clavier Hervé , Nolan Steven P. 
Published: December 2008

AbstractA comparative study examining the catalytic activity of a series of five indenylidene‐containing ruthenium complexes in olefin cross‐metathesis reactions is presented. Results reveal the greater efficiency of precatalyst 5, highlighting the key role of the N,N′‐bis(2,6‐diisopropylphenyl)imidazol‐2‐ylidene (IPr) ligand for this transformation. The scope of this precatalyst was investigated and several microwave experiments were carried out allowing for catalyst loadings as low as 0.1 mol%. Overall, cross‐metathesis products were isolated in moderate to excellent yields with high stereoselectivity.
β‐Hydroxycarboxylic Acids from Simple Ketones by Carboxylation and Asymmetric Hydrogenation
Authors: Flowers Brendan J. , Gautreau‐Service Robyn , Jessop Philip G. 
Published: December 2008

AbstractWe present a new asymmetric synthesis of β‐hydroxycarboxylic acids from ketones, performed by carboxylation using CO2 followed by asymmetric hydrogenation. First, the carboxylation of ketones gives β‐ketocarboxylic acids. The effects of temperature, reaction time, and amount of 1,8‐diazabicyclo[5.4.0]undec‐7‐ene (DBU) promoter on the carboxylation were investigated. The DBU can be recycled. For the second step, the asymmetric hydrogenation of these β‐ketocarboxylic acids, we determined the effect of solvent choice, H2 pressure, and substrate substitution. Hydrogenation yield and enantioselectivity are solvent‐dependent, and the mechanism could proceed through hydrogenation of either the enol or the keto forms of the bound substrate. This synthesis is industrially advantageous due to the limited number of reactants required, their low‐cost, and the potential for recycling unused materials.
Eco‐Friendly Olefin Dihydroxylation Catalyzed by Diphenyl Diselenide
Authors: Santoro Stefano , Santi Claudio , Sabatini Michela , Testaferri Lorenzo , Tiecco Marcello 
Published: December 2008

AbstractThe first general and efficient diphenyl diselenide‐catalyzed dihydroxylation of double bonds is presented. Hydrogen peroxide can be used as the oxidizing agent, affording generally good yields and high diasteroselectivity.
Wirkstofftransport mit weicher Materie: Matrix‐ und Vesikelvektoren
Authors: Soussan Elodie , Cassel Stéphanie , Blanzat Muriel , Rico‐Lattes Isabelle 
Published: December 2008

AbstractDer zunehmende Bedarf an Transportsystemen, mit denen die Aktivität und Spezifität von Wirkstoffen verbessert, die Toxizität reduziert und so die Behandlungssicherheit maximiert werden kann, hat zur Entwicklung zahlreicher Wirkstoffvektoren geführt. Insbesondere Systeme auf der Basis von weicher Materie verfügen über interessante Merkmale. Hier beschreiben wir den aktuellen Kenntnisstand in diesem Gebiet, wobei wir uns hauptsächlich auf die beiden Gruppen der Matrixsysteme und Vesikel konzentrieren. Wir geben eine Übersicht über die Strukturen, Eigenschaften und Einsatzmöglichkeiten dieser Vektoren und diskutieren die wichtigsten Vor‐ und Nachteile bei ihrer Synthese.
Heterogeneously Hybridized Porous Coordination Polymer Crystals: Fabrication of Heterometallic Core–Shell Single Crystals with an In‐Plane Rotational Epitaxial Relationship
Authors: Furukawa Shuhei , Hirai Kenji , Nakagawa Keiji , Takashima Yohei , Matsuda Ryotaro , Tsuruoka Takaaki , Kondo Mio , Haruki Rie , Tanaka Daisuke , Sakamoto Hirotoshi , Shimomura Satoru , Sakata Osami , Kitagawa Susumu 
Published: December 2008

AbstractMOF im MOF: Einkristalle eines porösen Kern‐Schale‐Koordinationspolymers (PCP) wurden durch epitaxiales Wachstum in Lösung erzeugt. Synchrotron‐Röntgenbeugungsmessungen offenbarten die strukturellen Beziehungen zwischen dem Kern‐ und Schalenkristall: Ein epitaxiales Wachstum in verdrehter Orientierung gleicht die unterschiedlichen Gitterkonstanten aus.magnified image
Chemoselective Ligation and Modification Strategies for Peptides and Proteins
Authors: Hackenberger Christian P. R. , Schwarzer Dirk 
Published: December 2008

AbstractThe investigation of biological processes by chemical methods, commonly referred to as chemical biology, often requires chemical access to biologically relevant macromolecules such as peptides and proteins. Building upon solid‐phase peptide synthesis, investigations have focused on the development of chemoselective ligation and modification strategies to link synthetic peptides or other functional units to larger synthetic and biologically relevant macromolecules. This Review summarizes recent developments in the field of chemoselective ligation and modification strategies and illustrates their application, with examples ranging from the total synthesis of proteins to the semisynthesis of naturally modified proteins.
Solid‐State Scrolls from Hierarchical Self‐Assembly of T‐Shaped Rod–Coil Molecules
Authors: Hong Dong‐Je , Lee Eunji , Jeong Haemi , Lee Jeong‐kyu , Zin Wang‐Cheol , Nguyen Trung Dac , Glotzer Sharon C. , Lee Myongsoo 
Published: December 2008

AbstractOn a roll: Attachment of flexible coils to the middle of a rigid rod generates T‐shaped rod–coil molecules that self‐assemble into layers that roll up to form filled cylindrical and hollow tubular scrolls, depending on the coil length, in the solid state (see picture); the rods are arranged parallel to the layer plane.magnified image
The role of trust in promoting organizational knowledge seeking using knowledge management systems: An empirical investigation
Authors: He Wei , Fang Yulin , Wei Kwok‐Kee 
Published: December 2008

AbstractKnowledge Management Systems (KMS) have become increasingly popular as a knowledge‐sharing tool in contemporary corporations. Enticing employees to seek knowledge from KMS remains an important concern for researchers and practitioners. Trust has been widely recognized in many studies as an important enabling factor for seeking knowledge; however, the role of trust in promoting knowledge‐seeking behavior using KMS has not been adequately addressed. Drawing upon the extant literature on trust and information technology adoption, this article examines the relationships between the knowledge seekers' trust in the community of KMS users, their perceptions toward the system (perceived usefulness and perceived seeking efforts), and the intention to continually use the KMS. The results reveal that trust in the community of KMS users does not directly affect the employees' knowledge‐seeking continuance intention; rather, it happens indirectly through a mediated effect of perceived usefulness of the KMS. Furthermore, we find that trust seems to be a stronger determinant of perceived usefulness than of perceived seeking efforts. Our study thus demonstrates the indirect, but still crucial, role of trust in knowledge‐seeking behavior in the context of corporate KMS usage. Other findings and the implications of this study for both researchers and practitioners are correspondingly discussed.
Inclusion Behavior of β‐Cyclodextrin with Bipyridine Molecules: Factors Governing Host‐Guest Inclusion Geometries
Authors: Zhao Yan‐Li , Benítez Diego , Yoon Il , Stoddart J. Fraser 
Published: December 2008

AbstractGuest Effect: The differences of nitrogen atom positions and the bridge bonds linked to two pyridine rings of some bipyridine guests can significantly affect the binding abilities and inclusion geometries of β‐cyclodextrin with the guests in both the solution and solid states.magnified imageThe 1:1 complexation of β‐cyclodextrin (β‐CD) with structurally similar bipyridine guests which lead to the formation of six inclusion complexes (1–6) of β‐CD with 4,4′‐vinylenedipyridine, 2,2′‐vinylenedipyridine, 1‐(2‐pyridyl)‐2‐(4‐pyridyl)ethylene, 4,4′‐ethylene‐dipyridine, 4,4′‐dithiodipyridine, and 2,2′‐dithiodipyridine has been investigated comprehensively by X‐ray crystallography in the solid state and by 1H NMR spectroscopy and microcalorimetric titration in aqueous solution. The complex formation constants (KS) for the stoichiometric 1:1 host–guest inclusion complexation of β‐CD with the bipyridine derivatives were determined in aqueous solution by microcalorimetry and the host–guest inclusion geometries of the complexes were deduced from 1H ROESY NMR spectroscopy. It transpires that the guest bipyridine molecules are included in the β‐CD cavity with a range of different inclusion geometries. In the solid state, the crystal superstructures for the β‐CD complexes 1, 4, and 5 are characterized by the triclinic crystal system (space group P1) commensurate with AAAA type supramolecular aggregation. By contrast, the β‐CD complexes 2, 3, and 6 display either monoclinic (space group P21) or orthorhombic (space group C2221) crystal systems, characteristic of ABAB type supramolecular aggregation. The results demonstrate that the relative locations of the nitrogen atom positions and the bridge‐bond links between the two pyridine rings in these bipyridine guests, not only lead to distinct crystal systems and space groups, but also to different binding geometries and thermodynamical parameters on complexation of the bipyridines with β‐CD. The knowledge obtained from this research improves our understanding of the molecular recognition and self‐assembly processes exhibited by β‐CD, both in the solid state and in aqueous solution.
900 MHz modulated electromagnetic fields accelerate the clathrin‐mediated endocytosis pathway
Authors: Moisescu Mihaela G. , Leveque Philippe , Verjus Marie‐Ange , Kovacs Eugenia , Mir Lluis M. 
Published: December 2008

AbstractWe report new data regarding the molecular mechanisms of GSM‐induced increase of cell endocytosis rate. Even though endocytosis represents an important physical and biological event for cell physiology, studies on modulated electromagnetic fields (EMF) effects on this process are scarce. In a previous article, we showed that fluid phase endocytosis rate increases when cultured cells are exposed to 900 MHz EMF similar to mobile phones' modulated GSM signals (217 Hz repetition frequency, 576 µs pulse width) and to electric pulses similar to the GSM electrical component. Trying to distinguish the mechanisms sustaining this endocytosis stimulation, we exposed murine melanoma cells to Lucifer Yellow (LY) or to GSM–EMF/electric pulses in the presence of drugs inhibiting the clathrin‐ or the caveolin‐dependent endocytosis. Experiments were performed at a specific absorption rate (SAR) of 3.2 W/kg in a wire patch cell under homogeneously distributed EMF field and controlled temperature (in the range of 28.5–29.5 °C). Thus, the observed increase in LY uptake was not a thermal effect. Chlorpromazine and ethanol, but not Filipin, inhibited this increase. Therefore, the clathrin‐dependent endocytosis is stimulated by the GSM–EMF, suggesting that the cellular mechanism affected by the modulated EMF involves vesicles that detach from the cell membrane, mainly clathrin‐coated vesicles. Bioelectromagnetics 30:222–230, 2009. © 2008 Wiley‐Liss, Inc.
Stable Long‐Term Intracellular Labelling with Fluorescently Tagged Cationic Magnetoliposomes
Authors: Soenen Stefaan J. H. , Vercauteren Dries , Braeckmans Kevin , Noppe Wim , De Smedt Stefaan , De Cuyper Marcel 
Published: December 2008

AbstractIron oxide nanocrystals that are dextran coated are widely exploited biomedically for magnetic resonance imaging (MRI), hyperthermia cancer treatment and drug or gene delivery. In this study, the use of an alternative coating consisting of a phospholipid bilayer directly attached to the magnetite core is described. The flexible nature of the magnetoliposome (ML) coat, together with the simple production procedure, allows rapid and easy modification of the coating, offering many exciting possibilities for the use of these particles in biomedical applications. Upon incubation of neutral MLs with an equimolar amount of cationic 1,2‐distearoyl‐3‐trimethylammoniumpropane (DSTAP)‐bearing vesicles, approximately one third of the cationic lipids are incorporated into the ML coat. This is in line with a theoretical model predicting transferability of only the outer leaflet phospholipids of bilayer structures. Most interestingly, the use of MLs containing 3.33 % DSTAP with a positive ζ‐potential of (31.3±7.3) mV (mean ±SD) at neutral pH, results in very heavy labelling of a variety of biological cells (up to (70.39±4.52) pg of Fe per cell, depending on the cell type) without cytotoxic effects. The results suggest the general applicability of these bionanocolloids for cell labelling. Mechanistically, the nanoparticles are primarily taken up by clathrin‐mediated endocytosis and follow the endosomal pathway. The fate of the ML coat after internalisation has been studied with different fluorescent lipid conjugates, which because of the unique features of the ML coat can be differentially incorporated in either the inner or the outer layer of the ML bilayer. It is shown that, ultimately, iron oxide cores surrounded by an intact lipid bilayer appear in endosomal structures. Once internalised, MLs are not actively exocytosed and remain within the cell. The lack of exocytosis and the very high initial loading of the cells by MLs result in a highly persistent label, which can be detected, even in highly proliferative 3T3 fibroblasts, for up to at least one month (equivalent to approximately 30 cell doublings), which by far exceeds any values reported in the literature.
In vitro Synthesis of New Cyclodepsipeptides of the PF1022‐Type: Probing the α‐D‐Hydroxy Acid Tolerance of PF1022 Synthetase
Authors: Müller Jane , Feifel Sven C. , Schmiederer Timo , Zocher Rainer , Süssmuth Roderich D. 
Published: December 2008

AbstractThe nonribosomal peptide synthetase PF1022‐synthetase (PFSYN) synthesises the cyclooctadepsipeptide PF1022 from the building blocks D‐lactate, D‐phenyllactate and N‐methylleucine. The substrate tolerance of PFSYN for hydroxy acids was probed by in vitro screening of a set of aliphatic and aromatic α‐D‐hydroxy acids with various structural modifications in the side chain. Thus, new PF1022 derivatives for example, propargyl‐D‐lactyl‐PF1022 and β‐thienyl‐D‐lactyl‐PF1022 were generated. The promiscuous behaviour of PFSYN towards aliphatic and aromatic α‐D‐hydroxy acids is considerably larger than that of related enniatin synthetase (ESYN) and thus gives rise to the enzymatic generation of various new PF1022 derivatives.
Ultrafast Internal Conversion in a Model Anthocyanin–Polyphenol Complex: Implications for the Biological Role of Anthocyanins in Vegetative Tissues of Plants
Authors: Rodrigues Rita França , Ferreira da Silva Palmira , Shimizu Karina , Freitas Adilson A. , Kovalenko Sergey A. , Ernsting Nikolaus P. , Quina Frank H. , Maçanita António 
Published: December 2008

AbstractThe red flavylium cations of anthocyanins form ground‐state charge‐transfer complexes with several naturally occurring electron‐donor copigments, such as hydroxylated flavones and hydroxycinnamic or benzoic acids. Excitation of the 7‐methoxy‐4‐methyl‐flavylium–protocatechuic acid complex results in ultrafast (240 fs) internal conversion to the ground state of the complex by way of a low‐lying charge‐transfer state. Thus, both uncomplexed anthocyanins, whose excited state decays by fast (5–20 ps) excited‐state proton transfer, and anthocyanin–copigment complexes have highly efficient mechanisms of deactivation that are consistent with the proposed protective role of anthocyanins against excess solar radiation in the vegetative tissues of plants.
Synthesis and Characterization of 2‐Mono‐ and 1,2‐Diaminocarba‐closo‐dodecaborates M[1‐R‐2‐H2N‐closo‐CB11H10] (R=H, Ph, H2N, CyHN)
Authors: Finze Maik 
Published: December 2008

AbstractThe first primary 2‐aminocarba‐closo‐dodecaborates [1‐R‐2‐H2N‐closo‐CB11H10]− (R=H (1), Ph (2)) have been synthesized by insertion reactions of (Me3Si)2NBCl2 into the trianions [7‐R‐7‐nido‐CB10H10]3−. The difunctionalized species [1,2‐(H2N)2‐closo‐CB11H10] (3) and 1‐CyHN‐2‐H3N‐closo‐CB11H10 (H‐4) have been prepared analogously from (Me3Si)2NBCl2 and 7‐H3N‐7‐nido‐CB10H12. In addition, the preparation of [Et4N][1‐H2N‐2‐Ph‐closo‐CB11H10] ([Et4N]‐5) starting from PhBCl2 and 7‐H3N‐7‐nido‐CB10H12 is described. Methylation of the [1‐Ph‐2‐H2N‐closo‐CB11H10]− ion (2) to produce 1‐Ph‐2‐Me3N‐closo‐CB11H10 (6) is reported. The crystal structures of [Et4N]‐2, [Et4N]‐5, and 6 were determined and the geometric parameters were compared to theoretical values derived from DFT and ab initio calculations. All new compounds were studied by NMR, IR, and Raman spectroscopy, MALDI mass spectrometry, and elemental analysis. The discussion of the experimental NMR chemical shifts and of selected vibrational band positions is supported by theoretical data. The thermal properties were investigated by differential scanning calorimetry (DSC). The pKa values of 2‐H3N‐closo‐CB11H11 (H‐1), 1‐H3N‐closo‐CB11H10 (H‐7), and 1,2‐(H3N)2‐closo‐CB11H10 (H2‐3) were determined by potentiometric titration and by NMR studies. The experimental results are compared to theoretical data (DFT and ab initio). The basicities of the aminocarba‐closo‐dodecaborates agree well with the spectroscopic and structural properties.
ChemInform Abstract: BaN3Cl: Synthesis, Crystal Structure, Vibrational Spectra and Thermal Decomposition of Barium Azide Chloride.
Authors: Blaschkowski Bjoern , Balzer Harald , Keller Hans‐Lothar , Schleid Thomas 
Published: December 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: SrNi2Ge and SrNi3Ge2 — Two Related Hexagonal Germanides.
Authors: Hlukhyy Viktor , Faessler Thomas F. 
Published: December 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis of NASICON — A Molecular Precursor‐Based Approach.
Authors: Porkodi P. , Yegnaraman V. , Kamaraj P. , Kalyanavalli V. , Jeyakumar D. 
Published: December 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: An Open‐Framework Thorium Sulfate Hydrate with 11.5 Å Voids.
Authors: Wilson Richard E. , Skanthakumar S. , Knope Karah E. , Cahill Christopher L. , Soderholm L. 
Published: December 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Solution Identification and Solid State Characterization of a Heterometallic Polyoxometalate {Mo11V7}: [MoVI11VV5V IV2O52(μ9‐SO3)] 7‐.
Authors: Miras Haralampos N. , Stone Daniel J. , McInnes Eric J. L. , Raptis Raphael G. , Baran Peter , Chilas George I. , Sigalas Michael P. , Kabanos Themistoklis A. , Cronin Leroy 
Published: December 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: SnxPt4SnySb12‐y: A Skutterudite with Covalently Bonded Filler.
Authors: Liang Y. , Borrmann H. , Baenitz M. , Schnelle W. , Budnyk S. , Zhao J. T. , Grin Yu. 
Published: December 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: The First Example of Enamine—Lewis Acid Cooperative Bifunctional Catalysis: Application to the Asymmetric Aldol Reaction.
Authors: Arnold Kenny , Batsanov Andrei S. , Davies Bryan , Grosjean Christophe , Schuetz Thorben , Whiting Andrew , Zawatzky Kerstin 
Published: December 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Xphos Ligand and Platinum Catalysts: A Versatile Catalyst for the Synthesis of Functionalized β‐(E)‐Vinylsilanes from Terminal Alkynes.
Authors: Hamze Abdallah , Provot Olivier , Brion Jean‐Daniel , Alami Mouad 
Published: December 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Silica‐Immobilized Second Generation Hoveyda—Grubbs: A Convenient, Recyclable and Storageable Heterogeneous Solid Catalyst.
Authors: Van Berlo Boris , Houthoofd Kristof , Sels Bert F. , Jacobs Pierre A. 
Published: December 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Highly Atom Efficient Aluminum Triflate Catalyzed Acetal Formation.
Authors: Williams D. Bradley G. , Lawton Michelle C. 
Published: December 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Ruthenium‐Catalyzed Synthesis of Secondary Alkylamines: Selective Alkylation with Aliphatic Amines.
Authors: Baehn Sebastian , Hollmann Dirk , Tillack Annegret , Beller Matthias 
Published: December 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Multicomponent Reaction Design: A One‐Pot Route to Substituted Di‐O‐acylglyceric Acid Amides from α‐Diazoketones.
Authors: Fan Lijun , Adams Ashley M. , Ganem Bruce 
Published: December 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.