bluuebunny/crossref_metadata_2025_split huggingface dataset:
High‐Performance GdNiO3Epitaxial Film Memristor for Neuralactivity Analysis
Authors: Bai Bing , Liu Gongjie , Sun Yong , Liu Pan , Zhao Zhen , Guo Zhenqiang , Yan Xiaobing 
Published: February 2024

AbstractPerovskite‐type rare earth nickelates based memristor have recently attracted extensive attention in the field of novel storage computing due to their special electronic structure and exotic physical properties. However, there is still a shortage of memristors with ultra‐high stability performance, which will provide a solid foundation for future neural network computing with high accuracy recognition rates. Here, a GdNiO3‐based interfacial memristor is presented, which possesses ultra‐high stable performance, such as electroforming‐free, low device‐to‐device variation, reliable cyclic switching, high on/off ratio (≈104) and stable pulse modulation of conduction. Combined with the comprehensive microstructure results, this behavior is ascribed to the interface Schottky barrier variation caused by the 1D oxygen vacancy channel conduction according to the transmission electron microscopy results. In particular, based on the device's stable pulse modulation plasticity performance, the study also succeeds in achieving highly accurate neural firing pattern recognition up to ≈99.75% accuracy and monitoring of pattern transitions by implementing a reservoir computing system based on the device. This research advances the progress of nickelates in novel storage computing and paves the way for future efficient memristor‐based reservoir computing systems to handle more complex temporal tasks.
Advanced Nanoarchitectonics of Drug Delivery Systems with Pyroptosis Inhibition for Noncancerous Disease Treatment
Authors: You Qian Yi , Hu Ming Dong , Qian Hang 
Published: February 2024

AbstractProgrammed cell death (PCD) is a controlled and organized form of death regulated by genes, allowing cells to adapt to their environment. Pyroptosis, a recently discovered type of programmed cell death, differs from apoptosis and necrosis. It is characterized by the activation of caspase and the cleavage of gasdermin. Many studies have focused on understanding the mechanisms and roles of pyroptosis, particularly in cancer research. While inducing pyroptosis in tumor cells for cancer treatment is a major research focus, it is equally important to explore methods of reducing pyroptosis in noncancerous diseases. Recent advancements in drug delivery systems, specifically nanoarchitectonics, offer site‐specific targeting, prolonged drug circulation, enhanced efficacy, improved solubility, and better absorption. Although several reviews have described how nanoarchitectonics can trigger pyroptosis in tumor cells, little attention is given to their potential to inhibit pyroptosis in noncancerous diseases. Therefore, it is crucial to bridge this gap and explore the future directions for utilizing nanoarchitectonics as a powerful tool against noncancerous diseases. This review aims to delve into the recent progress made in nanoarchitectonics‐based advanced drug delivery systems for the treatment of noncancerous diseases by reducing pyroptosis, while also highlighting potential future perspectives in this emerging field.
Coal Tar Pitch Derived sp2 Configuration‐Dominated Vacancy‐Rich Carbon with Expand Interlayer Spacing for Low‐Voltage, Durable, and Fast Potassium Storage
Authors: Jiang Yu , Xiao Nan , Song Xuedan , Xiao Jian , Yu Kai , Dai Xuehui , Lv Zhidong , Qiu Jieshan 
Published: February 2024

AbstractThe low‐voltage charging capacity and rate performance are two crucial but mutually restricted properties of K‐ion batteries. Herein, a sulfonamide and amide linkages‐triggered N doping high‐temperature removal strategy is proposed to obtain porous carbon with rich carbon vacancies, high sp2 hybridized C content (65.3%), and large interlayer spacing using coal tar pitch as carbon precursor. Carbon vacancies and sp2 hybridized C are proved to be not only active sites for low‐voltage potassium storage but also conducive to the fast transfer of ions and electrons, endowing reversible and fast potassium storage at low voltage. Moreover, abundant carbon vacancies and large carbon interlayer spacing alleviate volume variation, improving the cycling stability for 8500 cycles (about 3700 h). This work sheds new light on the design of low‐voltage, durable, and fast potassium storage carbon anodes, and promotes the development of practical carbon anodes for high energy density K‐ion batteries in the future.
Hierarchical Design of Tissue‐Mimetic Fibrillar Hydrogel Scaffolds
Authors: Pardo Alberto , Gomez‐Florit Manuel , Davidson Matthew D. , Öztürk‐Öncel Meftune Özgen , Domingues Rui M. A. , Burdick Jason A. , Gomes Manuela E. 
Published: February 2024

AbstractMost tissues of the human body present hierarchical fibrillar extracellular matrices (ECMs) that have a strong influence over their physicochemical properties and biological behavior. Of great interest is the introduction of this fibrillar structure to hydrogels, particularly due to the water‐rich composition, cytocompatibility, and tunable properties of this class of biomaterials. Here, the main bottom‐up fabrication strategies for the design and production of hierarchical biomimetic fibrillar hydrogels and their most representative applications in the fields of tissue engineering and regenerative medicine are reviewed. For example, the controlled assembly/arrangement of peptides, polymeric micelles, cellulose nanoparticles (NPs), and magnetically responsive nanostructures, among others, into fibrillar hydrogels is discussed, as well as their potential use as fibrillar‐like hydrogels (e.g., those from cellulose NPs) with key biofunctionalities such as electrical conductivity or remote stimulation. Finally, the major remaining barriers to the clinical translation of fibrillar hydrogels and potential future directions of research in this field are discussed.
A Versatile Chitosan‐Based Hydrogel Accelerates Infected Wound Healing via Bacterial Elimination, Antioxidation, Immunoregulation, and Angiogenesis
Authors: Zhang Ye , Chen Sinan , Qin Xian , Guo Ai , Li Kai , Chen Lixue , Yi Weiwei , Deng Zhongliang , Tay Franklin R. , Geng Wenbo , Miao Li , Jiao Yang , Tao Bailong 
Published: February 2024

AbstractDrug‐resistant bacterial infection of cutaneous wounds causes great harm to the human body. These infections are characterized by a microenvironment with recalcitrant bacterial infections, persistent oxidative stress, imbalance of immune regulation, and suboptimal angiogenesis. Treatment strategies available to date are incapable of handling the healing dynamics of infected wounds. A Schiff base and borate ester cross‐linked hydrogel, based on phenylboronic acid‐grafted chitosan (CS‐PBA), dibenzaldehyde‐grafted poly(ethylene glycol), and tannic acid (TA), is fabricated in the present study. Customized phenylboronic acid‐modified zinc oxide nanoparticles (ZnO) are embedded in the hydrogel prior to gelation. The CPP@ZnO‐P‐TA hydrogel effectively eliminates methicillin‐resistant Staphylococcus aureus (MRSA) due to the pH‐responsive release of Zn2+ and TA. Killing is achieved via membrane damage, adenosine triphosphate reduction, leakage of intracellular components, and hydrolysis of bacterial o‐nitrophenyl‐β‐d‐galactopyranoside. The CPP@ZnO‐P‐TA hydrogel is capable of scavenging reactive oxygen and nitrogen species, alleviating oxidative stress, and stimulating M2 polarization of macrophages. The released Zn2+ and TA also induce neovascularization via the PI3K/Akt pathway. The CPP@ZnO‐P‐TA hydrogel improves tissue regeneration in vivo by alleviating inflammatory responses, stimulating angiogenesis, and facilitating collagen deposition. These findings suggest that this versatile hydrogel possesses therapeutic potential for the treatment of MRSA‐infected cutaneous wounds.
Strengthening the Metal–Acid Interactions by Using CeO2 as Regulators of Precisely Placing Pt Species in ZSM‐5 for Furfural Hydrogenation
Authors: Zhao Meng , Wang Xiao , Xu Jing , Li Yuou , Wang Xiaomei , Chu Xiang , Wang Ke , Wang Zijian , Zhang Ling‐ling , Feng Jing , Song Shuyan , Zhang Hongjie 
Published: February 2024

AbstractUnderstanding the synergism between the metal site and acid site is of great significance in boosting the efficiency of bi‐functional catalysts in many heterogeneous reactions, particularly in biomass upgrading. Herein, a “confined auto‐redox” strategy is reported to fix CeO2‐anchored Pt atoms on the inner wall of a ZSM‐5 cage, achieving the target of finely controlling the placements of the two active sites. Compared with the conventional surface‐supported counterpart, the encapsulated Pt/CeO2@ZSM‐5 catalyst possesses remarkably‐improved activity and selectivity, which can convert >99% furfural into cyclopentanone with 97.2% selectivity in 6 h at 160 °C. Besides the excellent catalytic performance, the ordered metal–acid distribution also makes such kind of catalyst an ideal research subject for metal–acid interactions. The following mechanization investigation reveals that the enhancement is strongly related to the unique encapsulation structure, which promotes the migration of the reactants over different active sites, thereby contributing to the tandem reaction.
Dual External Electron Injection Barrier Layers Enable High‐Performance Near‐Infrared Organic Photodetectors Realizing Real‐Time Heart Rate Monitoring
Authors: Tang Haoran , He Zeyu , Zhang Hengyuan , Du Xiaoyang , Yu Xin , Cao Luye , Lin Hui , Yang Gang , Zheng Caijun , Tao Silu 
Published: February 2024

AbstractNear‐infrared organic photodetectors (NIR‐OPDs) play important roles in medical monitoring, bio‐imaging and night vision, etc. Among them, bulk heterojunction (BHJ)‐based photodiode type NIR‐OPDs exhibit extraordinary characteristics in photoresponse and photosensitivity. However, their dark current density (Jd) often increases severely as the bias voltage increases, which seriously reduces detection sensitivity for NIR light. Here, a novel structure of dual external electron injection barrier layers (DEBLs) composed of “m‐MTDATA/DPEPO:HAT‐CN” is proposed to overcome this challenge. For DEBLs, a barrier is established with high injection barrier and long effective injection barrier width to prevent external electrons injection under bias voltage for suppressing Jd (4.22 × 10−8 A cm−2 better than 1.47 × 10−5 A cm−2 of the traditional device at −2 V). More importantly, photo‐generated carriers have almost no loss through DEBLs. Therefore, high and stable detectivity (D*) over 1013 Jones are realized under 850 nm from 0 V to nearly −1 V and even far over 1012 Jones at −2 V. More strikingly, the structure of DEBLs is proven to be effective and universal in NIR‐OPDs and the device based on it successfully realize the real‐time heart rate monitoring of various human states, which exhibits great potential in human health monitoring.
Dynamic Band‐Alignment Modulation in MoTe2/SnSe2 Heterostructure for High Performance Photodetector
Authors: Zhang Fen , Shi Hao , Yu Yali , Liu Shuo , Liu Duanyang , Zhou Xinyun , Yuan Le , Shi Jiaqi , Xia Qinglin , Wei Zhongming , He Jun , Zhong Mianzeng 
Published: February 2024

AbstractFor two‐dimensional (2D) layered material heterojunctions, dynamic modulation of band alignments allows for the design of devices with flexible multi‐functional applications. In this paper, a device structure is presented based on a MoTe2/SnSe2 field‐effect transistor. By applying a bias voltage to the electrostatic gate, the gate voltage is adjusted from negative to positive, causing the heterojunction to transition from type‐III band alignment to type‐II band alignment. The working mechanism and device performance of the heterojunctions with different band alignments are investigated. The device exhibited outstanding detection range (from ultraviolet to infrared), detectivity (2.42 × 109 Jones), and speed (1.3 ms). Under a positive gate voltage, a higher ratio of light current to dark current (2×103) is achieved. To further demonstrate the potential of the high‐performance devices, their reliability is confirmed through their performance in image recognition using deep learning.
Development of pH‐Sensitive Film for Detection of Implant Infection via Ultrasound Luminescent Chemical Imaging
Authors: Schober Gretchen B. , Uzair Unaiza , Reel Morgan , Abbaraju Vigjna , Behlow Herbert , Rao Apparao M. , Bhattacharya Sriparna , Anker Jeffrey N. 
Published: February 2024

AbstractA new hybrid ultrasound luminescent chemical imaging technique is described along with a pH sensor to image chemical concentrations at the surface of implanted medical devices. The purpose is to detect and study local biochemistry during infection. The sensor comprises a mechanoluminescent film (SrAl2O4:Eu, Dy microphosphors embedded in a biocompatible polymer film) and a pH indicator dye. A focused ultrasound beam generates green luminescence at the ultrasound focal point. By pulsing the ultrasound ON and OFF, the modulated luminescence can be distinguished from persistent luminescence, for high spatial resolution imaging. A red fluorescent dye and the pH indicator dye bromothymol blue are added to the coating to modulate the red‐light transmittance via pH dependent absorbance. Acidosis is observed as an increase in red luminescence intensity in spectroscopy and imaging. The films are sensitive to biologically relevant changes in pH (6.0–8.0) and can be imaged through optically scattering media to mimic tissue. The images have a knife edge spatial resolution of ≈3 mm through optically scattering phantoms, limited by the focused ultrasound spot size. This novel technique may permit the elucidation of implant infection at the implant surface and can be further developed for the measurement of other relevant chemical species in the future.
Bis‐Alkoxide Dysprosium(III) Crown Ether Complexes Exhibit Tunable Air Stability and Record Energy Barrier
Authors: Xu Wen‐Jie , Luo Qian‐Cheng , Li Zi‐Han , Zhai Yuan‐Qi , Zheng Yan‐Zhen 
Published: February 2024

AbstractHigh‐performance and air‐stable single‐molecule magnets (SMMs) can offer great convenience for the fabrication of information storage devices. However, the controversial requisition of high stability and magnetic axiality is hard to balance for lanthanide‐based SMMs. Here, a family of dysprosium(III) crown ether complexes possessing hexagonal‐bipyramidal (pseudo‐D6h symmetry) local coordination geometry with tunable air stability and effective energy barrier for magnetization reversal (Ueff) are shown. The three complexes share the common formula of [Dy(18‐C‐6)L2][I3] (18‐C‐6 = 1,4,7,10,13,16‐hexaoxacyclooctadecane; L = I, 1; L = OtBu 2 and L = 1‐AdO 3). 1 is highly unstable in the air. 2 can survive in the air for a few minutes, while 3 remains unchanged in the air for more than 1 week. This is roughly in accordance with the percentage of buried volumes of the axial ligands. More strikingly, 2 and 3 show progressive enhancement of Ueff and 3 exhibits a record high Ueff of 2427(19) K, which significantly contributes to the 100 s blocking temperature up to 11 K for Yttrium‐diluted sample, setting a new benchmark for solid‐state air‐stable SMMs.
Regioselective Arylation of Amidoaryne Precursors via Ag‐Mediated Intramolecular Oxy‐Argentation
Authors: Kwon Yong‐Ju , Kong Ye‐Jin , Lee Min‐Jung , Lim Eun‐Hye , Kwak Jaesung , Kim Won‐Suk 
Published: February 2024

AbstractAn unprecedented silver‐mediated intramolecular oxy‐argentation of 3‐amidoaryne precursors that quickly generates a heteroarylsilver species is developed. AgF acts as both a stoichiometric fluoride source and a reagent for the formation of a benzoxazolylsilver intermediate via aryne generation. Pd‐catalyzed coupling reactions of (hetero)aryl iodides with a silver species, generated in situ, allow for the synthesis of various C7‐arylated benzoxazoles. As a result, an aryl group is selectively introduced into the meta‐position of 3‐amidobenzyne precursors. Mechanistic studies have indicated the presence of a benzoxazolylsilver intermediate and revealed that the reaction proceeds via an intramolecular oxy‐argentation process, which is initiated by a direct fluoride attack on the silyl group.
Unveiling the Role of Side Chain for Improving Nonvolatile Characteristics of Conjugated Polymers‐Based Artificial Synapse
Authors: Sung Junho , Chung Sein , Jang Yongchan , Jang Hyoik , Kim Jiyeon , Lee Chan , Lee Donghwa , Jeong Dongyeong , Cho Kilwon , Kim Youn Sang , Kang Joonhee , Lee Wonho , Lee Eunho 
Published: February 2024

AbstractInterest has grown in services that consume a significant amount of energy, such as large language models (LLMs), and research is being conducted worldwide on synaptic devices for neuromorphic hardware. However, various complex processes are problematic for the implementation of synaptic properties. Here, synaptic characteristics are implemented through a novel method, namely side chain control of conjugated polymers. The developed devices exhibit the characteristics of the biological brain, especially spike‐timing‐dependent plasticity (STDP), high‐pass filtering, and long‐term potentiation/depression (LTP/D). Moreover, the fabricated synaptic devices show enhanced nonvolatile characteristics, such as long retention time (≈102 s), high ratio of Gmax/Gmin, high linearity, and reliable cyclic endurance (≈103 pulses). This study presents a new pathway for next‐generation neuromorphic computing by modulating conjugated polymers with side chain control, thereby achieving high‐performance synaptic properties.
Efficient WO3 Nanoplate Arrays Photoanode Modified by ZnO Nanosheets for Enhanced Charge Separation and Transfer to Promote Photoelectrochemical Performances
Authors: Wu Weihao , Yan Zhehui , Wang Lijun , Zhu Xiangrong , Zhu Yongheng , Liao Guihong , Zhu Luping 
Published: February 2024

AbstractA key factor in the photoelectrochemical (PEC) performance of photoelectrodes is the efficient separation and transfer of photogenerated charges. Herein, a novel photoanode comprising three‐dimensional (3D) WO3 nanoplate@ZnO nanosheet hierarchical type‐II heterojunction arrays (3D WO3@ZnO HHAs) is designed and constructed via modification of the WO3 nanoplate arrays with ZnO nanosheets. The synthesized materials are characterized viaX‐ray diffraction (XRD), ultraviolet and visible spectrophotometry (UV–vis), scanning electon microscopy (SEM), transmission electron microscopy (TEM), and X‐ray photoelectron spectroscopy (XPS) analyses. Photoelectrochemical (PEC) test results reveal that the synthesized 3D WO3@ZnO HHAs photoanode exhibits reduced charge transfer resistance, improved electron‐hole pair life, and enhanced photocurrent density (≈4.5 times increase in comparison to that of the bare WO3). The increased light capture and high surface area in contact with the electrolyte as well as the enhanced charge transfer through the synergy between morphology and band structures may be responsible for the improved PEC characteristics.
Visualization of temperature distribution and flow behavior in water evaporation using water‐soluble spiropyran
Authors: Wang Wenjing , Wan Sibo , Chen Yahui , Fang Yu , Lu Sheng , Gu Hao , Li Yourong , Chen Xiaoqiang 
Published: February 2024

AbstractUnderstanding the convection flows driven by the uneven temperature distribution in heated aqueous solutions is fascinating and meaningful both in fundamental and industrial aspects. Therefore, it is desirable to develop a simple and convenient method for real‐time tracking of surface temperature distribution and the solvent flow state. Herein, we designed and screened a water‐soluble spiropyran derivative (BS‐SP1) that contains benzothiazole and sulfonic acid groups. The BS‐SP1 molecule was found to exceptionally maintain the reversible photochromic characteristics in water, and then served as a photo‐responsive indicator for visualizing the temperature distribution and flow behavior on water surface with high resolution. This study provides feasible guidance on the dynamic self‐assembly and thermodynamics occurring in the water evaporation system and offers a practical tool for investigating these behaviors.
Condition‐dependent NOx adsorption/desorption over Pd/BEA: A combined microreactor and in situ DRIFTS study
Authors: Chen Junjie , Lee Jungkuk , Khatri Prateek , Toops Todd J. , Kyriakidou Eleni A. 
Published: February 2024

AbstractPd/BEA is chosen as a model passive NOx adsorber (PNA) to elucidate the effect of the feed gas composition on the NOx adsorption/desorption behavior. The Brønsted acid and the partially hydrolyzed framework Al (P‐HAl(OH)) sites in HBEA adsorb NO and NO2 under dry conditions. Moreover, the performance of HBEA is not affected by CO, while CO inhibits nitrate formation and promotes NO adsorption via the Pd(NO)(CO) complexes formation over Pd/BEA. H2O inhibits NO adsorption over the Brønsted acid and P‐HAl(OH) sites, and ionic Pd is the only active site for NOx adsorption under wet conditions. Furthermore, NO adsorption over hydrated Pd (Pd2+(OH)(NO)(H2O)3) is weaker than NO adsorption over bare ionic Pd (Z2[Pd2+(NO)], Z[Pd2+(OH)(NO)]). Dehydration of Pd2+(OH)(NO)(H2O)3 forms more stable Z[Pd2+(OH)(NO)] during desorption. The NO adsorption capacity of Pd/BEA improves in the presence of CO under both dry and wet conditions by forming a stable carbonyl–nitrosyl complex.
The impact of sex on platelet responses to aspirin in patients with peripheral artery disease
Authors: Suarez Ferreira Sasha P. , Hall Ryan P. , Morrow Katherine , Patel Shiv , Lee Ivy , Hagos Fanah , Zacharias Nikolaos , Machlus Kellie , Dua Anahita 
Published: February 2024

AbstractWomen with peripheral artery disease (PAD) have poorer limb salvage outcomes in spite of having lower risk factors for vascular disease than their male counterparts. Mono antiplatelet therapy with aspirin is the cornerstone of medical treatment for PAD to reduce the risk of arterial thrombosis, but platelets in women may have a variable response to this standard of care compared to men. Viscoelastic assays, such as thromboelastography with platelet mapping (TEG‐PM), have been utilized to identify prothrombotic states and may provide insight into a patient's real‐time coagulation profile and their response to specific antiplatelet medications. The aim of this prospective, observational study was to delineate the sex differences in platelet function using TEG‐PM in patients with PAD on aspirin post‐revascularization for PAD. All patients with PAD undergoing revascularization on aspirin monotherapy were prospectively enrolled between December 2020 and September 2023. The cohort was divided by sex, demographics, medications, procedure type, and outcomes were documented. Serial perioperative TEG‐PM assays (1, 3, and 6 months) were performed up to 6 months postoperatively and platelet function was evaluated in both groups. Statistical analysis between women and men was performed to identify sex‐specific differences in platelet function. Over the study period, a total of 303 patients were enrolled. Of this cohort, 149 patients met the study criteria and 266 samples were analyzed; 52 (34.89%) were women and 97 (65.11%) were men. In the platelet mapping assay, women showed significantly greater MAActF and MAAA, than men (16.66 vs. 14.94, p < .03 and 37.26 vs. 32.38, p < .01, respectively) indicating stronger thrombotic propensity. Additionally, platelet inhibition was significantly lower in women compared to men (52.95% vs. 61.65%, p < .05). In clinical outcomes reported as thrombotic events, women showed significantly higher occlusion in the area of intervention than men (4 vs. 1, p < .05). There is a growing awareness of the variations in the natural course, underlying mechanisms, and resulting outcomes of cardiovascular conditions, including PAD, in relation to sex. In this study, women did not achieve the same levels of platelet inhibition and displayed a procoagulant tendency in comparison to men when administered aspirin. Overall, aspirin monotherapy may be potentially sufficient for men, but women may require increased doses and/or additional antiplatelet medications to achieve an equivalent therapeutic effect.