bluuebunny/crossref_metadata_2025_split huggingface dataset:
Cartilaginous tissue formation from bone marrow cells using rotating wall vessel (RWV) bioreactor
Authors: Ohyabu Yoshimi , Kida Naoko , Kojima Hiroko , Taguchi Tetsushi , Tanaka Junzo , Uemura Toshimasa 
Published: September 2006

AbstractThis is the first successful report of the rapid regeneration of three‐dimensional large and homogeneous cartilaginous tissue from rabbit bone marrow cells without a scaffold using a rotating wall vessel (RWV) bioreactor, which simulates a microgravity environment for cells. Bone marrow cells cultured for 3 weeks in DMEM were resuspended and cultured for 4 weeks in the chondrogenic medium within the vessel. Large cylindrical cartilaginous tissue with dimensions of (1.25 ± 0.06) × (0.60 ± 0.08) cm (height × diameter) formed. Their cartilage marker expression was confirmed by mRNA expressions of aggrecan, collagen type I and II, and glycosaminoglycan (GAG)/DNA ratio. Their cartilaginous properties were demonstrated by toluidine blue, safranin‐O staining, and polarization. © 2006 Wiley Periodicals, Inc.
Influence of pH, temperature, and urea molar flowrate on Arthrospira platensis fed‐batch cultivation: A kinetic and thermodynamic approach
Authors: Sánchez‐Luna Luis Dante , Bezerra Raquel Pedrosa , Matsudo Marcelo Chuei , Sato Sunao , Converti Attilio , de Carvalho João Carlos Monteiro 
Published: September 2006

AbstractArthrospira platensis was cultivated photoautotrophically at 6.0 klux light intensity in 5.0‐L open tanks, using a mineral medium containing urea as nitrogen source. Fed‐batch experiments were performed at constant flowrate. A central composite factorial design combined to response surface methodology (RSM) was utilized to determine the relationship between the selected response variables (cell concentration after 10 days, Xm, cell productivity, PX, and nitrogen‐to‐cell conversion factor, YX/N) and codified values of the independent variables (pH, temperature, T, and urea flowrate, K). By applying the quadratic regression analysis, the equations describing the behaviors of these responses as simultaneous functions of the selected independent variables were determined, and the conditions for Xm and PX optimization were estimated (pH 9.5, T = 29°C, and K = 0.551 mM/day). The experimental data obtained under these conditions (Xm = 749 mg/L; PX = 69.9 mg/L·day) were very close to the estimated ones (Xm = 721 mg/L; PX = 67.1 mg/L·day). Additional cultivations were carried out under the above best conditions of pH control and urea flowrate at variable temperature. Consistently with the results of RSM, the best growth temperature was 29°C. The maximum specific growth rates at different temperatures were used to estimate the thermodynamic parameters of growth (ΔH* = 59.3 kJ/mol; ΔS* = −0.147 kJ/mol·K; ΔG* = 103 kJ/mol) and its thermal inactivation (ΔH = 72.0 kJ/mol; ΔS = 0.144 kJ/mol·K; ΔG = 29.1 kJ/mol). Biotechnol. Bioeng. 2007;96:702–711. © 2006 Wiley Periodicals, Inc.
Protective effect of α‐tocopherol on oxidative stress in experimental pulmonary fibrosis in rats
Authors: Deger Yeter , Yur Fatmagul , Ertekin Ali , Mert Nihat , Dede Semiha , Mert Handan 
Published: September 2006

AbstractThe study was undertaken to investigate the influence of α‐tocopherol (vitamin E) on malondialdehyde (MDA) and glutathione (GSH) levels and catalase (CAT) activity in lung of rats with bleomycin‐induced pulmonary fibrosis (PF). Fourteen Wistar–albino rats were randomly divided into two groups of seven animals each. The first group was treated intra‐tracheally with bleomycin hydrochloride (BM group); the second group was also instilled with BM but received injections of α‐tocopherol twice a week (BM + E group). The third group was treated in the same manner with saline solution only, acting as controls (C). There were decreases in GSH level and CAT activity while an increase in MDA level in BM group was found compared to the control group (p < 0.05). Vitamin E had a regulator effect on these parameters. After administration of α‐tocopherol, the increase in GSH level and CAT activity and the decrease in MDA level were seen in BM + E group compared to BM group (p < 0.05). Distinct histopathological changes were found in the BM group compared to the untreated rats. Less severe fibrotic lesions were also observed in the BM + E group. The results show that vitamin E is effective on the prevention of BM‐induced PF, as indicated by differences in the lung levels of oxidants and antioxidants. Copyright © 2006 John Wiley & Sons, Ltd.
Effect of cerebrocrast, a new long‐acting compound on blood glucose and insulin levels in rats when administered before and after STZ‐induced diabetes mellitus
Authors: Briede J. , Stivrina M. , Stoldere Dz. , Vigante B. , Duburs G. 
Published: September 2006

AbstractInsulin‐dependent diabetes mellitus (IDDM) is an autoimmune disease that is characterized by selective destruction of insulin secreting pancreatic islets β‐cells. The formation of cytokines (IL‐1β, IL‐6, TNF‐α, etc.) leads to extensive morphological damage of β‐cells, DNA fragmentation, decrease of glucose oxidation, impaired glucose‐insulin secretion and decreased insulin action and proinsulin biosynthesis. We examined the protective effect of a 1,4‐dihydropyridine (DHP) derivative cerebrocrast (synthesized in the Latvian Institute of Organic Synthesis) on pancreatic β‐cells in rats possessing diabetes induced with the autoimmunogenic compound streptozotocin (STZ). Cerebrocrast administration at doses of 0.05 and 0.5 mg/kg body weight (p.o.) 1 h or 3 days prior to STZ as well as at 24 and 48 h after STZ administration partially prevented pancreatic β‐cells from the toxic effects of STZ, and delayed the development of hyperglycaemia. Administration of cerebrocrast starting 48 h after STZ‐induced diabetes in rats for 3 consecutive days at doses of 0.05 and 0.5 mg/kg body weight (p.o.) significantly decreased blood glucose level, and the effect remained 10 days after the last administration. Moreover, in these rats, cerebrocrast evoked an increase of serum immunoreactive insulin (IRI) level during 7 diabetic days as compared to both the control normal rats and the STZ‐induced diabetic control rats. The STZ‐induced diabetic rats that received cerebrocrast had a significantly high serum IRI level from the 14th to 21st diabetic days in comparison with the STZ‐induced diabetic control.The IRI level in serum as well as the glucose disposal rate were significantly increased after stimulation of pancreatic β‐cells with glucose in normal rats that received cerebrocrast, administered 60 min before glucose. Glucose disposal rate in STZ‐induced diabetic rats as a result of cerebrocrast administration was also increased in comparison with STZ‐diabetic control rats. Administration of cerebrocrast in combination with insulin intensified the effect of insulin. The hypoglycaemic effect of cerebrocrast primarily can be explained by its immunomodulative properties. Moreover, cerebrocrast can act through extrapancreatic mechanisms that favour the expression of glucose transporters, de novo insulin receptors formation in several cell membranes as well as glucose uptake. Copyright © 2006 John Wiley & Sons, Ltd.
New Compounds Ln(Zn,Al)8 and Yb4Zn20.3Al12.7 and Their Crystal Structures.
Authors: Stel'makhovych Ol'ga , Kuz'ma Yurij 
Published: September 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Structurally Complex Cobalt Intermetallics Grown from Liquid Aluminum: Co19Al45Si10‐x (x = 0.13) and Co5Al14Si2.
Authors: Wu Xiuni , Latturner Susan , Kanatzidis Mercouri G. 
Published: September 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Lewis Acids Activated with Molecular Oxygen: Dinuclear Molybdenum Complexes for Aza‐Diels—Alder Reactions of Acyl Hydrazones.
Authors: Yamashita Yasuhiro , Salter Matthew M. , Aoyama Kayoko , Kobayashi Shu 
Published: September 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
One‐Pot Coupling of Two Alkynes and One Alkene for Formation of Cyclohexene Derivatives via Zirconacyclopentadienes.
Authors: Zhou Lishan , Xi Chanjuan , Wang Hui , Kong Fanzhi , Takahashi Tamotsu 
Published: September 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Synthesis of Novel Benzochromene, Benzoquinoline, Benzochromenopyrimidine and Pyrimidobenzoquinoline Derivatives.
Authors: Jachak M. N. , Kendre D. B. , Avhale A. B. , Toche R. B. , Medhane V. J. 
Published: September 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Facile β‐Alkyl and β‐Hydride Elimination in the Nickel‐Catalyzed Annulation of o‐Iodophenyl Ketones and Aldehydes with Bicyclic Alkenes.
Authors: Shukla Paritosh , Cheng Chien Hong 
Published: September 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Practical, Catalytic, Asymmetric Synthesis of β‐Lactones via a Sequential Ketene Dimerization/Hydrogenation Process: Inhibitors of the Thioesterase Domain of Fatty Acid Synthase.
Authors: Purohit Vikram C. , Richardson Robyn D. , Smith Jeffrey W. , Romo Daniel 
Published: September 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Cyclocondensation Reactions of Heterocyclic Carbonyl Compounds. Part 12. The Double Course of Cyclization of 3‐(2‐Aminobenzyl)‐1,2‐dihydro‐quinoxaline‐2‐one.
Authors: Frysova Iveta , Lycka Antonin , Slouka Jan , Hlavac Jan 
Published: September 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Syntheses Based on 8‐Substituted 3‐Bromoacetyl‐3,8‐dimethyl‐2,7‐dioxaspiro[4,4]nonane‐1,6‐diones.
Authors: Kochikyan T. V. , Harutyunyan E. V. , Harutyunyan V. S. , Avetisyan A. A. 
Published: September 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Synthesis of New Derivatives of 1,2,4‐Triazol‐3‐one.
Authors: Struga M. , Dobosz M. , Kossakowski J. , Dybala I. , Stepniak K. , Koziol A. E. 
Published: September 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Facile Preparation and the Crystal Structure of N,N′‐Dialkyl‐2,6‐pyridinedimethanaminium Halide.
Authors: Kobayashi Tohru , Yaita Tsuyoshi , Sugo Yumi , Suda Hiroki , Suzuki Shinji , Fujii Yuki , Nakano Yoshiharu 
Published: September 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Synthesis of Novel Halo‐oxybispyridines, New Building Blocks in Cholinergic Medicinal Chemistry.
Authors: Voisin Anne Sophie , Bouillon Alexandre , Lancelot Jean‐Charles , Lesnard Aurelien , Rault Sylvain 
Published: September 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Unusual Structure Derived from N‐Acridin‐9‐yl Methyl N′‐Acridin‐9‐yl Thiourea Based on the Propensity of N‐10 to Retain H.
Authors: Klika Karel D. , Imrich Jan , Vilkova Maria , Bernat Juraj , Pihlaja Kalevi 
Published: September 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
1,3‐Dihydro‐2H‐imidazo[4,5‐c]pyridin‐2‐one.
Authors: Holt Jarle , Bakke Jan M. , Fiksdahl Anne 
Published: September 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Heterocyclic Analogues of Pleiadiene. Part 75. Formylation of Perimidines and 2,2‐Dimethyl‐2,3‐dihydroperimidine under Vilsmeier Conditions.
Authors: Filatova E. A. , Borovlev I. V. , Pozharskii A. F. , Goncharov V. I. , Demidov O. P. 
Published: September 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Synthesis, Structure Analysis, and Antitumor Activity of 3,6‐Disubstituted‐1,4‐dihydro‐1,2,4,5‐tetrazine Derivatives.
Authors: Rao Guo‐Wu , Hu Wei‐Xiao 
Published: September 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Array Synthesis of Progesterone Receptor Antagonists: 3‐Aryl‐1,2‐diazepines.
Authors: Wiethe Robert W. , Stewart Eugene L. , Drewry David H. , Gray David W. , Mehbob Abdul , Hoekstra William J. 
Published: September 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Synthesis of Novel 5‐Hydroxyalkenylphosphonates by Addition of Aromatic Aldehydes to Zirconacyclopentenylphosphonates.
Authors: Quntar Abed Al Aziz , Rosenthal David , Srebnik Morris 
Published: September 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Kadsutherins A—C: Three New Dibenzocyclooctane Lignans from the Stems of Kadsura Species
Authors: Lu Yan , Chen Daofeng 
Published: September 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Rapid Stereocontrolled Assembly of the Fully Substituted C‐Aryl Glycoside of Kendomycin with a Prins Cyclization: A Formal Synthesis.
Authors: Bahnck Kevin B. , Rychnovsky Scott D. 
Published: September 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Flexible Docking of Ligands into Synthetic Receptors Using a Two‐Sided Incremental Construction Algorithm.
Authors: Steffen Andreas , Kaemper Andreas , Lengauer Thomas 
Published: September 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Ensemble Docking into Flexible Active Sites. Critical Evaluation of FlexE Against JNK‐3 and β‐Secretase.
Authors: Polgar Timea , Keserue Gyoergy M. 
Published: September 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
The Combinatorial Approach to Asymmetric Hydrogenation: Phosphoramidite Libraries, Ruthenacycles, and Artificial Enzymes
Authors: de Vries Johannes G. , Lefort Laurent 
Published: September 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Recent Advances in the Chemistry of Triaryl‐ and Triheteroarylmethanes
Authors: Nair Vijay , Thomas Siji , Mathew Smitha C. , Abhilash K. G. 
Published: September 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Synthesis, Structure and Magnetism of Metal‐Organic Framework Materials with Doubly Pillared Layers
Authors: Jia Hong‐Peng , Li Wei , Ju Zhan‐Feng , Zhang Jie 
Published: September 2006

AbstractTwo novel coordination polymers with a 3D pillared‐layer framework, [MII(Tdc)(4,4′‐Bpy)]n [M = Fe (1), Co (2); Tdc = thiophene‐2,5‐dicarboxylate; 4,4′‐Bpy = 4,4′‐bipyridine), have been hydrothermally synthesised and structurally characterised. A simultaneous reduction of iron(III) to iron(II) occurs under hydrothermal conditions in the self‐assembly process of complex 1. The complexes are isostructural and, in each complex, the metal ions are linked by double μ2‐carboxylate bridges in a syn‐syn mode, giving rise to dinuclear units that are connected to each other by chelating carboxylate groups from the Tdc ligands in an approximately perpendicular orientation to form 2D rectangle‐grid layers. The adjacent layers are held together through 4,4′‐Bpy molecules in a double‐pillar support fashion to give a 3D network with three intersecting perpendicular channels. Variable‐temperature magnetic susceptibility measurements revealed weak antiferromagnetic coupling interactions in both complexes and a field‐induced magnetic transition can be observed in 2.(© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2006)
Complexation of Uranium(VI) with Thiodiacetic Acid in Solution at 10–85 °C
Authors: Di Bernardo Plinio , Zanonato PierLuigi , Bismondo Arturo , Jiang Huijian , Garnov Alexander Yu. , Jiang Jun , Rao Linfeng 
Published: September 2006

AbstractThe protonation of thiodiacetate and its complexation with uranium(VI) in 1.05 mol kg–1 NaClO4 are studied at variable temperatures (10–85 °C). Three UVI complexes (UO2L, UO2HL+, and UO2HL2–, where L is thiodiacetate) are identified in this temperature range. The formation constants and the enthalpies of complexation are determined by potentiometry and calorimetry. The complexation of uranium(VI) with thiodiacetate becomes more endothermic at higher temperatures. However, the complexes become stronger due to increasingly more positive entropies of complexation at higher temperatures, which exceeds the increase in the unfavorable enthalpy of complexation. The values of the heat capacity of complexation (ΔCp°) are 122 ± 16, 302 ± 26, and 242 ± 23 J K–1 mol–1 for UO2L, UO2HL+, and UO2HL2–, respectively. The effect of temperature on the thermodynamics of the complexation is discussed in terms of the electrostatic model and the change in the solvent structure. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2006)
Size‐ and Shape‐Controlled Synthesis and Assembly of a Silver Nanocomplex in UV‐Irradiated TSA Solution
Authors: Yang Liangbao , Shen Yuhua , Xie Anjian , Liang Jianjun , Li Shikuo , Zhang Qingfeng 
Published: September 2006

AbstractIn this paper we describe the size‐controlled synthesis ofa silver nanocomplex based on the reduction of silvernitrate (AgNO3) by UV‐irradiated tungstosilicate acid [H4(SiW12O40), TSA] solution. This method allows the synthesis of ellipsoidal particles with an average size that is tunable between 2.4 and 84 nm by varying the molar ratio of silver nitrate to TSA, the pH of the reaction solution, and the reaction temperature. Silver nanorods can be formed from the ellipsoidal nanoparticles by controlling the aging time. The formation mechanism of these nanorods is also discussed. The nanoparticles are characterized by UV/Vis spectroscopy, FTIR spectroscopy, XRD analysis, XPS, electron diffraction (ED), TEM, and with a Zetasizer instrument. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2006)
Lead Halide Layers Linked by trans‐Cu(Gly)2 (Gly = –O2C–CH2–NH2) Pillars in Heterometallic Glycinate Based Organic–Inorganic Hybrids
Authors: Bi Wenhua , Mercier Nicolas , Louvain Nicolas , Latroche Michel 
Published: September 2006

AbstractThe novel hybrid compounds Pb2Cu(O2C–CH2–NH2)2X4 (X = Br, Cl) were prepared and characterized by single‐crystal X‐ray diffraction. TA analysis and DSC measurements show that the compounds are stable up to 200 °C. As in hybrid perovskites, their layered structures are based on metal(II) halide 2D frameworks, which are here covalently linked by trans‐Cu(Gly)2 flat SBUs. These rigid pillars are able to accommodate some of the void that exists in between the PbX2 layers. However, the results from hydrogen absorption experiments that were conducted at 77 K indicate that the hybrids are not good candidates for absorption materials. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2006)
The Preparation and Absolute Configurations of Enantiomerically Pure C4‐Symmetric Tetraalkoxyresorcin[4]arenes Obtained from Camphorsulfonate Derivatives
Authors: Buckley Benjamin R. , Page Philip C. Bulman , Chan Yohan , Heaney Harry , Klaes Michael , McIldowie Matthew J. , McKee Vickie , Mattay Jochen , Mocerino Mauro , Moreno Eduardo , Skelton Brian W. , White Allan H. 
Published: September 2006

AbstractThe preparation of a series of diastereoisomeric tetracamphorsulfonates derived from racemic tetramethoxyresorcin[4]arenes was achieved by reactions with an excess of (S)‐(+)‐10‐camphorsulfonyl chloride in pyridine followed by isolation using flash chromatography. Tetradeprotonation of a number of tetramethoxyresorcin[4]arenes using n‐butyllithium in tetrahydrofuran, followed by reactions using (S)‐(+)‐10‐camphorsulfonyl chloride, gave the same tetracamphorsulfonates. Mono‐, di‐ and tricamphorsulfonates were also prepared following selective deprotonation. In the reactions with tetraisopropyloxy‐ and tetracyclopentyloxyresorcin[4]arenes, only the mono‐ and dicamphorsulfonates were formed. X‐ray crystallographic analysis established the absolute configurations of three diastereoisomerically pure tetracamphorsulfonates, including a diastereoisomer prepared from 6,12,18,24‐tetramethoxy‐2,8,14,20‐tetrakis(2‐methylpropyl)resorcin[4]arene. An additional pair of diastereoisomers was also prepared using (R)‐(–)‐10‐camphorsulfonyl chloride and 6,12,18,24‐tetramethoxy‐2,8,14,20‐tetrakis(2‐methylpropyl)resorcin[4]arene, for one of which the structure was confirmed by an additional X‐ray structure determination. Hydrolytic removal of the camphorsulfonyl residue(s) from the various diastereoisomers gave enantiomers of known absolute configurations. In some cases, the chiral nonracemic tetraalkoxyresorcin[4]arenes were converted into known tetrabenzoxazine derivatives by using N,N‐bis(methoxymethyl)[(S)‐(–)‐(α‐methylbenzyl)]amine in thermal or microwave‐assisted reactions. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2006)