bluuebunny/crossref_metadata_2025_split huggingface dataset:
ChemInform Abstract: Preparation of Chiral 4‐Substituted γ‐Lactams and the Corresponding γ‐Aminobutyric Acids
Authors: Lebedev A. 
Published: January 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Transition Metal Catalyzed Carbon—Silicon Bond Forming Reactions Using Chlorosilanes Promoted by Grignard Reagents
Authors: Terao Jun , Kambe Nobuaki 
Published: January 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Nucleophilic Addition Reactions of Aryl and Alkenylboronic Acids and Their Derivatives to Imines and Iminium Ions
Authors: Batey Robert A. 
Published: January 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Recent Advances in the Preparation of Allylboronates and Their Use in Tandem Reactions with Carbonyl Compounds
Authors: Kennedy Jason W. J. , Hall Dennis G. 
Published: January 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Metal‐Catalyzed Borylation of Alkanes and Arenes via C—H Activation for the Synthesis of Boronic Esters
Authors: Ishiyama Tatsuo , Miyaura Norio 
Published: January 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: The Use of Chiral Oxazolines in Early C‐C Bond Forming Reactions
Authors: Meyers Albert I. 
Published: January 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Algorithm‐Based Methods for the Discovery of Novel Multicomponent Reactions
Authors: Weber Lutz 
Published: January 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Non Camphor Based Sultam Chiral Auxiliaries
Authors: Lee Albert W. M. , Chan W. H. , Zhang Shu‐Jia , Zhang Hong‐Kui 
Published: January 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Henry′s Law Coefficients for Chlorine‐Containing C1 and C2 Hydrocarbons
Authors: Warneck Peter 
Published: January 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Aggregation‐ and Crystallization‐Induced Light Emission
Authors: Hong Yuning , Dong Yongqiang , Tong Hui , Li Zhen , Haeussler Matthias , Lam Jacky Wing Yip , Tang Ben Zhong 
Published: January 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Tautomerism of β‐Dicarbonyl and β,β′′‐Tricarbonyl Compounds in Protogenic Media: The Prototropy of Hydroxonium Derivatives of Keto‐Enols
Authors: Gulyakevich O. V. , Mikhal'chuk A. L. 
Published: January 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Genomic Analyses and the Origin of the Eukaryotes
Authors: Rivera Maria C. 
Published: January 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Will We Soon Be Fueling Our Automobiles with Ammonia—Borane?
Authors: Marder Todd B. 
Published: January 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Fullerenes: Multitask Components in Molecular Machinery
Authors: Mateo‐Alonso Aurelio , Guldi Dirk M. , Paolucci Francesco , Prato Maurizio 
Published: January 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Femtosecond Lasers for Quantum Information Technology
Authors: de Vivie‐Riedle Regina , Troppmann Ulrike 
Published: January 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Acid Catalysts in Industrial Hydrocarbon Chemistry
Authors: Busca Guido 
Published: January 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Computational Chemistry of Polyatomic Reaction Kinetics and Dynamics: The Quest for an Accurate CH5 Potential Energy Surface
Authors: Albu Titus V. , Espinosa‐Garcia Joaquin , Truhlar Donald G. 
Published: January 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Electron Spin Resonance Spectroscopy
Authors: Weckhuysen Bert M. , Heidler Ralf , Schoonheydt Robert A. 
Published: January 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: The Chemistry of the Solid Earth
Authors: Pulford Ian D. 
Published: January 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Zinc‐Binding Groups Modulate Selective Inhibition of MMPs
Authors: Agrawal Arpita , Romero‐Perez Diego , Jacobsen Jennifer A. , Villarreal Francisco J. , Cohen Seth M. 
Published: January 2008

AbstractThe need for selective matrix metalloproteinase (MMP) inhibition is of interest because of the range of pathologies mediated by different MMP isoforms. The development of more selective MMP inhibitors (MMPi) may help to overcome some of the undesired side effects that have hindered the clinical success of these compounds. In an effort to devise new approaches to selective inhibitors, herein we describe several novel MMPi and show that their selectivity is dependent on the nature of the zinc‐binding group (ZBG). This is in contrast to most current MMPi, which obtain isoform selectivity solely from the peptidomimetic backbone portion of the compound. In the present study, six different hydroxypyrone and hydroxypyridinone ZBGs were appended to a common biphenyl backbone and the inhibition efficiency of each inhibitor was determined in vitro (IC50 values) against MMP‐1, ‐2, ‐3, ‐7, ‐8, ‐9, ‐12, and ‐13. The results show that the selectivity profile of each inhibitor is different as a result of the various ZBGs. Computational modeling studies were used to explain some trends in the observed selectivity profiles. To assess the importance of the ZBG in a biological model, two of the semiselective, potent MMPi (and one control) were evaluated using an isolated perfused rat heart system. Hearts were subjected to ischemia reperfusion injury, and recovery of contractile function was examined. In this model, only one of the two MMPi showed significant and sustained heart recovery, demonstrating that the choice of ZBG can have a significant effect in a relevant pathophysiological endpoint.
Distribution of serotonin in the trunk of Metaperipatus blainvillei (Onychophora, Peripatopsidae): Implications for the evolution of the nervous system in Arhropoda
Authors: Mayer Georg , Harzsch Steffen 
Published: January 2008

AbstractOnychophora (“velvet worms”) are a key taxon in the discussion of arthropod phylogeny. Studies that analyze neuroanatomical characters against a phylogenetic background have recently provided new insights into this debate. However, to date only a few studies on nervous system organization, particularly in the trunk, are available in Onychophora. To close this gap and to compare the onychophoran nervous system with that of other bilaterians, we have analyzed the pattern of serotonin‐like immunoreactivity in Metaperipatus blainvillei (Peripatopsidae). In addition to confirming previous histological observations, our experiments revealed many new aspects of nervous system organization in Onychophora. The serotonergic nervous system of M. blainvillei consists of five longitudinal nerve strands (the paired dorsolateral nerves, the heart nerve, and the paired ventral cords), which are interconnected at regular intervals by ring commissures as well as median commissures. The ring commissures are absent in the leg‐bearing regions. In addition to the main nerve tracts, there are several extensive fiber networks innervating the integument, the nephridial organs, and the body musculature. The leg nerves and nephridial nerves represent the only strictly segmental neuronal structures. We conclude that the general architecture of the onychophoran nervous system in the trunk closely resembles the orthogonal organization that is present in various other groups of Bilateria, which suggests that the arthropod nervous system is derived from such an orthogonal pattern. This finding implies that the “rope ladder‐like” nervous system may have arisen independently in Panarthropoda and Annelida and does not represent a synapomorphy of these groups. J. Comp. Neurol. 507:1196–1208, 2008. © 2008 Wiley‐Liss, Inc.
Physical Properties of Biopolymers Assessed by Optical Tweezers: Analysis of Folding and Refolding of Bacterial Pili
Authors: Andersson Magnus , Axner Ove , Almqvist Fredrik , Uhlin Bernt Eric , Fällman Erik 
Published: January 2008

AbstractBacterial adhesion to surfaces mediated by specific adhesion organelles that promote infections, as exemplified by the pili of uropathogenic E. coli, is studied mostly at the level of cell–cell interactions and thereby reflects the averaged behavior of multiple pili. The role of pilus rod structure has therefore only been estimated from the outcome of experiments involving large numbers of organelles at the same time. It has, however, lately become clear that the biomechanical behavior of the pilus shafts play an important, albeit hitherto rather unrecognized, role in the adhesion process. For example, it has been observed that shafts from two different strains, even though they are similar in structure, result in large differences in the ability of the bacteria to adhere to their host tissue. However, in order to identify all properties of pilus structures that are of importance in the adhesion process, the biomechanical properties of pili must be assessed at the single‐molecule level. Due to the low range of forces of these structures, until recently it was not possible to obtain such information. However, with the development of force‐measuring optical tweezers (FMOT) with force resolution in the low piconewton range, it has lately become possible to assess forces mediated by individual pili on single living bacteria in real time. FMOT allows for a more or less detailed mapping of the biomechanical properties of individual pilus shafts, in particular those that are associated with their elongation and contraction under stress. This Mi‐ nireview presents the FMOT technique, the biological model system, and results from assessment of the biomechanical properties of bacterial pili. The information retrieved is also compared with that obtained by atomic force microscopy.
Accuracy of herpes simplex virus detection in liquid‐based (SurePath) Papanicolaou tests: A comparison with polymerase chain reaction
Authors: Aslan Deniz L. , Pambuccian Stefan E. , Prekker Frances L. , Schacker Timothy W. , Southern Peter , Savik Kay , McKeon Dan , Gulbahce H. Evin 
Published: January 2008

AbstractA review of our institution's Papanicolaou test records over an 11‐yr period showed that liquid‐based Papanicolaou tests (LBPTs) had a significantly higher frequency of diagnoses of Herpes simplex virus (HSV)‐related cellular changes compared to conventional Papanicolaou smears (77/302,841, 0.026% vs. 56/376,173, 0.015%, P = 0.002). To investigate the accuracy of the diagnosis of HSV by LBPT, we performed conventional polymerase chain reaction (PCR) on the residual samples from 258 prospectively collected LBPT and real‐time PCR using a different primer set on a subset of 40 LBPT. Conventional PCR was positive in 22 of 22 cases diagnosed of HSV, 1 of 2 cases diagnosed as suspicious for HSV, and none of 234 LBPT without a cytologic HSV diagnosis. Real‐time PCR was positive in 8 of 8 cases diagnosed as HSV and none of the 32 controls. We conclude that LBPT allows an increased detection of HSV that is highly accurate. Diagn. Cytopathol. 2008;36:94–103. © 2008 Wiley‐Liss, Inc.
Diagnosis of myeloid sarcoma involving salivary glands by fine‐needle aspiration cytology and flow cytometry: Report of four cases
Authors: Cai Guoping , Levine Pascale , Şen Filiz 
Published: January 2008

AbstractMyeloid sarcoma involving salivary glands is extremely rare. Here, we report four cases of this rare occurrance, diagnosed by fine‐needle aspiration biopsy. All of four patients had previous diagnoses of myeloid neoplasms. They presented with a solitary mass in the parotid or submandibular salivary gland. The cytological evaluation of the aspirates revealed scattered salivary gland acini admixed with dispersed atypical cells. In three cases, the atypical cells appeared to be heterogenous, intermediate to large in size, and have folded nuclei with fine chromatin. In another case the atypical cells were monotonous and had round nuclei with fine chromatin. The myeloid lineage of the atypical cells was demonstrated by flow cytometric analysis. High clinical suspicion, careful cytological evaluation, and concurrent ancillary studies are essential for establishing a diagnosis of myeloid sarcoma. Diagn. Cytopathol. 2008;36:124–127. © 2008 Wiley‐Liss, Inc.
Phosphaturic mesenchymal tumor diagnosed by fine‐needle aspiration and core biopsy: A case report and review of literature
Authors: Policarpio‐Nicolas Maria Luisa , Abbott Todd E. , Dalkin Alan C. , Bennett‐Wick Jane , Frierson Henry F. 
Published: January 2008

AbstractOncogenic (tumor‐induced) osteomalacia is a rare paraneoplastic syndrome of phosphate wasting that is frequently associated with phosphaturic mesenchymal tumor (PMT). As the cytologic features of this tumor apparently have not been reported, we describe the fine‐needle aspiration (FNA) findings for PMT that arose from the gluteal soft tissue in a patient with hypophosphatemia and multiple fractures secondary to osteomalacia. Smears from the computerized tomography (CT)‐guided FNA showed groups of spindle cells having elongated nuclei, fine to moderately coarsely granular chromatin, inconspicuous nucleoli, and delicate cytoplasm. Marked nuclear atypia, mitotic figures, and necrosis were absent. The differential diagnosis included a variety of benign and malignant spindle cell neoplasms such as monophasic synovial sarcoma, leiomyoma, peripheral nerve sheath tumor, fibrosarcoma, and, less likely, metastatic melanoma and sarcomatoid carcinoma. The bland‐appearing cytologic features of a spindle cell tumor in a patient with osteomalacia should suggest the diagnosis of PMT. Diagn. Cytopathol. 2008;36:115–119. © 2008 Wiley‐Liss, Inc.
Lithium and Zinc Complexes of C‐ and N‐Functionalized (2‐Pyridylmethyl)amines
Authors: Koch Christian , Kahnes Marcel , Schulz Martin , Görls Helmar , Westerhausen Matthias 
Published: January 2008

AbstractThe addition reaction of benzophenone with lithium (2‐pyridylmethyl)(tert‐butyldimethylsilyl)amide yields dimeric1‐lithoxy‐1,1‐diphenyl‐2‐(2‐pyridyl)‐2‐(trialkylsilylamino)ethane (1) with formation of a C–C bond. C‐Functionalized 2‐(pyridylmethyl)amines are accessible via the reaction of N‐(2‐pyridylmethylidene)phenylamine with diethylmalonate giving 2,2‐bis(ethoxycarbonyl)‐1‐(phenylamino)‐1‐(2‐pyridyl)ethane (2) which eliminates aniline upon heating yielding diethyl 2‐(2‐pyridylmethylidene)malonate (3). The addition of piperidine leads to the formation of the Michael type adduct 2,2‐bis(ethoxycarbonyl)‐1‐piperidyl‐1‐(2‐pyridyl)ethane (4) which can be deprotonated with metal‐organic reagents such as Zn[N(SiMe3)2]2, Zn[CH(SiMe3)2]2, LiN(SiMe3)2, and NaN(SiMe3)2 leading to 2,2‐bis(ethoxycarbonyl)‐1‐piperidyl‐1‐(2‐pyridyl)ethane‐2‐yl complexes of zinc (5 and 6), lithium (7), and sodium (8). N‐Functionalization can be achieved via the reaction of (2‐pyridylmethyl)(trialkylsilyl)amine with benzoyl chloride giving N‐(2‐pyridylmethyl)benzoylamine (9). Lithiation and subsequent salt metathesis reaction with another equivalent of benzoyl chloride yields N‐(2‐pyridylmethyl)dibenzoylamine (10). The addition reaction of ZnCl2 with N‐(2‐pyridylmethyl)(diphenylmethylidene)amine (11) forms colorless crystalline [(Py–CH2N=CPh2)ZnCl2] (12). The addition of benzoyl chloride leads to N‐(diphenylchloromethyl)‐N‐(2‐pyridylmethyl)benzoylamine (13). Addition of ZnCl2 leads to the formation of solvent‐separated [(2‐pyridylmethyl)(benzoylamino)diphenylcarbonium] [(tetrahydrofuran)trichlorozincate] (14). The X‐ray crystal structures of 1, 4 to 7, 9, 12, and 14 are discussed.(© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2008)
Stereoselective Desymmetrizations by Recombinant Whole Cells Expressing the Baeyer–Villiger Monooxygenase from Xanthobacter sp. ZL5: A New Biocatalyst Accepting Structurally Demanding Substrates
Authors: Rial Daniela V. , Bianchi Dario A. , Kapitanova Petra , Lengar Alenka , van Beilen Jan B. , Mihovilovic Marko D. 
Published: January 2008

AbstractIn this work the substrate profile and stereoselectivity of engineered whole cells overexpressing the Baeyer–Villiger monooxygenase from Xanthobacter sp. ZL5 with respect to biotransformations of prochiral substrates is characterized. This enzyme catalyzes the desymmetrization of cyclic ketones bearing different chemical features with stereoselectivity similar to that obtained with a related protein fromAcinetobacter as a prototype representative of the cyclohexanone monooxygenase enzyme cluster. Moreover, this biocatalyst is able to convert sterically demanding substrates previously not transformed by other enzymes with excellent enantioselectivities. These results expand the repertoire of optically pure lactones accessible by whole‐cell biotransformation processes, which are useful intermediates for the synthesis of natural and bioactive products. In addition, we observed a remarkable epoxidation reaction of a non‐activated C=C bond catalyzed by this monooxygenase.(© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2008)
Synthesis, Ion Complexation Study, and 3D‐Structural Analysis of Peptides Based on Crown‐Carrier, Cα‐Methyl‐L‐DOPA Amino Acids
Authors: Wright Karen , Anddad Rachid , Lohier Jean‐François , Steinmetz Vincent , Wakselman Michel , Mazaleyrat Jean‐Paul , Formaggio Fernando , Peggion Cristina , De Zotti Marta , Keiderling Timothy A. , Huang Rong , Toniolo Claudio 
Published: January 2008

AbstractSelected series of terminally protected model peptides to the hexamer level, based on four novel, crown‐ether containing Cα‐methyl‐L‐DOPA (L‐Mdp) amino acid residues, namely L‐Mdp[15‐C‐5], L‐Mdp[18‐C‐6], L‐Mdp[benzo‐24‐C‐8] and L‐Mdp[(S)‐Binol‐20‐C‐6], combined with either L‐Ala or L‐Ala/Aib or Gly/Aib, were synthesized by solution methods. An ESI‐MS analysis of their alkali metal cation complexation ability was carried out. Their FTIR absorption, 1H NMR, ECD, and VCD spectroscopic properties suggest that all of these crowned amino acids are strong inducers of (left‐handed) β‐turns and 310‐helical structures.(© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2008)
Ruthenium‐Catalyzed Allenyl Carbamate Formation from Propargyl Alcohols and Isocyanates
Authors: Haak Edgar 
Published: January 2008

AbstractRuthenium complexes of redox‐coupled cyclopentadienone ligands catalyze the formation of allenyl carbamates from propargyl alcohols and isocyanates. This efficient and atom‐economical process represents the first catalytic access to allenyl carbamates, compounds of high synthetic potential. The reaction needs an acidic co‐catalyst and can be performed at room temperature. In addition, new (cyclopentadienone)iron and ‐ruthenium complexes were synthesized, and mechanistic aspects regarding catalytic transformations of propargyl systems with ruthenium catalysts are obtained. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2008)