bluuebunny/crossref_metadata_2025_split huggingface dataset:
Sintomas somáticos funcionais em crianças atendidas na atenção primária à saúde
Authors: Do Prado Ana Paula , Pereira Padovani Flávia Helena 
Published: March 2024

Os sintomas somáticos funcionais se caracterizam como manifestações de natureza principalmente somática e do comportamento da criança, sem causa orgânica aparente. Em um período em que a capacidade de comunicação verbal é, ainda, limitada, a criança utiliza meios de comunicação não-verbal, por meio de seu corpo. O presente estudo tem por objetivo verificar a prevalência de sintomas somáticos funcionais em crianças de 6 a 36 meses em acompanhamento na atenção primária. Trata-se de um estudo observacional, de corte transversal e abordagem quantitativa. Foi composta uma amostra de conveniência com 40 díades mãe-criança, tendo como critérios de inclusão: crianças com idade de 6 a 36 meses de idade, em seguimento pediátrico de rotina na Atenção Primária à Saúde e mães com 18 anos ou mais, que aceitaram participar do estudo, mediante assinatura do TCLE. Para a realização da pesquisa, foram aplicados os instrumentos Questionário Sociodemográfico, elaborado para o estudo e Questionário de Sintomas Somáticos do Bebê, em um único encontro, aproveitando a ida da mãe e da criança à unidade de saúde para acompanhamento pediátrico de rotina. Foram realizadas análises descritivas dos distúrbios de comportamento entre as crianças. Os resultados preliminares apontam que a maioria das mães (95%) avalia de forma positiva a saúde geral do(a) filho(a), porém aproximadamente um terço delas (30%) avaliaram a qualidade do sono da criança como razoável ou ruim, seguida por avaliações negativas de respiração (25%), alimentação (22,5%), pele (20%), comportamento (15%) e digestão (10%). O estudo confirma a capacidade de identificação de sintomas somáticos funcionais na atenção primária à saúde.
The use of blockchain technology in law enforcement
Authors: Kiryushin Ivan Ivanovich , Ivanov Igor' Petrovich , Timofeev Viktor Vladimirovich , Zhmurko D Yu 
Published: March 2024

This article explores the possibilities of using blockchain technology in police work. Examples of the use of blockchain in various areas of police activity, such as personal data management, control of drug trafficking and other prohibited substances, traffic monitoring and the fight against cybercrime, are considered. The authors note that thanks to the storage of data in the blockchain, it becomes possible to increase the protection of the confidentiality of personal information, ensure transparency and efficiency of police work, as well as prevent fraud and corruption. The conclusion of the article emphasizes that the use of blockchain can improve the work of the police and ensure greater security of citizens. Distributed ledger technology, or blockchain as a service (BaaS) is indeed a relatively new product on the market that allows you to provide blockchain services for corporate clients. This solution allows you to use more reliable and secure methods of data processing and transaction management within the organization. All these economic effects can lead to a reduction in costs and an increase in the efficiency of the police. In general, the use of blockchain technology in the police can have a number of advantages, such as increasing transparency and accountability, reducing data processing time and combating data falsification. However, it is necessary to take into account some risks, such as the possibility of data privacy violations, as well as difficulties in integrating with existing systems and training personnel. In general, the introduction of blockchain technology into the police requires careful analysis and an approach that takes into account all aspects of the use of technology and its impact on the organization.
Simulating Allergic Rhinitis Infections in Adults with HIV/AIDS Using Runge-Kutta Fourth Order Method in SIR Model
Authors: Bulinda V. M. 
Published: March 2024

Simulating Allergic Rhinitis infections in Adults with HIV/AIDS using Runge-Kutta Fourth Order (RK4) Method in SIR Model is considered. Allergic rhinitis patients living with HIV/AIDS disease in adults is regarded as the target population. This condition is modeled through an SIR model with solutions solved using the RK4. The applied parameters and initial conditions in numerical simulations are carried out in this study in the literature. Application of the Runge-Kutta solutions provides the behaviour and visualization of the spread of allergic rhinitis infection for the patients living with HIV/AIDS disease in adults. The results suggest that after a given number of days, most of the population under investigation becomes infected with allergic rhinitis, which displaces the virus. Results are computed and analyzed using MATLAB computer software.
Administração do Desenvolvimento em Reginaldo Souza Santos
Authors: Santos Elinaldo Leal , Faria Alexandre 
Published: March 2024

A partir de uma abordagem decolonial busca-se apontar as contribuições de Reginaldo Souza Santos para o campo da Administração do Desenvolvimento (AD), evidenciando a sua tese de que após quase três séculos de avanços nas forças produtivas e no acúmulo de capital e do conhecimento, seria necessário uma inversão na lógica dominante do pensamento econômico sobre dinâmicas dominantes de desenvolvimento: deve haver distribuição de riqueza entre os extratos sociais “qualquer que seja o nível de renda (PQNR). Para tanto, retoma à história da AD na perspectiva do Sul Global para contextualizar o pensamento desse intelectual e pesquisador baiano não-branco que dedicou um longo período da sua vida em compreender processos de desenvolvimento da sociedade brasileira, no âmbito do pensamento crítico. O estudo nos revela que a proposta do PQNR sugerida por R. Santos centra-se em base teórico-metodológica de contraposição ao pensamento dominante do Norte Global.
Chama salvadora
Authors: Medeiros Júnior Geraldo 
Published: March 2024

O professor Reginaldo Souza Santos se notabilizou por seus escritos na área do conhecimento denominada por ele de Administração Política. No presente texto, em formato de depoimento, procura-se homenagear o professor, a partir das memórias do que ele significou na vida do autor. Trabalha-se aqui a importância enquanto autor reconhecido e também como amigo. O autor, criador de uma nova área da Administração, que mudou o curso dos estudos em vários momentos da profissional, incluindo a tese de doutorado do autor deste texto. Ideias como o conceito de Administração Política e a endogeneidade do Estado, foram e são importantes, norteadoras e transformadoras. O amigo, presente nas rodas de chopp, no papo franco, nas preocupações com o Brasil. Pode-se falar sobre a influência oriunda das diversas faces do professor Reginaldo. O presente texto procura relatar como a presença do professor Reginaldo Souza Santos veio a transformar os caminhos da vida profissional. Considera-se que a obra e os conselhos do professor representaram uma chama, revolucionária e salvadora, capaz de estimular e trazer novos caminhos a serem percorridos. Se por várias vezes ele chegou a salvar a vida do autor, um ano após a sua partida, ele continua unindo pessoas e acendendo a chama, da ciência, da indignação, da arte do encontro. A obra do professor Reginaldo Souza Santos é uma chama acesa. É uma obra inconclusa, que suscita entre seus colegas e admiradores desafios para a sua continuidade. Reginado Souza Santos vive.
Administração política e brasileira
Authors: Matos Martins Paulo Emílio 
Published: March 2024

Já na penúltima década do século XIX, Silvio Romero (1886) advertia sobre a necessidade de reconhecermos a nossa própria “individualidade, intelectual e política” para uma produção literária não mimética da forânea. A partir dos manifestos modernistas de Oswald de Andrade (1924, 1928) e da Redução Sociológica de Alberto Guerreiro Ramos (1965) este ensaio postula o resgate das interpretações do Brasil e do pensamento social brasileiro como referências bibliográficas nos Estudos Organizacionais em nosso ambiente acadêmico e na prática administrativa em geral. Tendo como corpus de análise aquelas obras e sua intertextualidade – ainda que defasadas três décadas as duas primeiras da última – e a partir da hipótese de um “descarrilamento onto-epistemo-metodológico” (Martins, 2023) da produção sobre Administração exportada do centro e reproduzida na periferia, o artigo sugere que a senda trilhada pioneiramente por Guerreiro Ramos (1966) – na análise do formalismo no Brasil – e, mais recentemente, os trabalhos de três grupos de pesquisa acadêmica nacionais: Núcleo de Estudos de Administração Brasileira (ABRAS), o Programa de Pós-Graduação em Administração (PPGAd)/Universidade Federal Fluminense (UFF) de 1988 em diante Administração Política Brasileira, Núcleo de Pós-Graduação em Administração (NPGA)/ Universidade Federal da Bahia (UFBA) (a partir de 1993) e Organização e Práxis Libertadora Programa de Pós-Graduação em Administração (PPGA) / Universidade Federal do Rio Grande do Sul (UFRGS) (2003 até a presente data), podem resgatar o clamor do Manifesto Antropófago de Andrade. Quem sabe (?), inicia-se, assim, o “banquete do padre Sardinha” dos Estudos Organizacionais de Pindorama?
Endogenous sex hormones, cognitive decline, and future dementia in old men
Authors: Geerlings Mirjam I. , Strozyk Dorothea , Masaki Kamal , Remaley Alan T. , Petrovitch Helen , Ross G. Webster , White Lon R. , Launer Lenore J. 
Published: July 2006

AbstractObjective:To estimate the association of endogenous levels of bioavailable testosterone and estradiol with risk for cognitive decline and dementia in old men.Methods:Within the population‐based, prospective Honolulu‐Asia Aging Study, 2,974 men, aged 71 to 93 years, without dementia were reexamined 3 times over an average of 6 years for development of dementia and cognitive decline. Cognitive decline was measured with the Cognitive Abilities Screening Instrument. Incident dementia was diagnosed according to standard criteria. A total of 134 men experienced development of Alzheimer's disease (AD; including 40 cases with contributing cerebrovascular disease) and 44 experienced development of vascular dementia.Results:Adjusting for age and other covariates, testosterone was not associated with risk for dementia (using Cox regression analyses) or cognitive decline (using random coefficient analyses). However, higher levels of estradiol were associated with risk for AD (hazard ratio per standard deviation increase, 1.25; 95% confidence interval, 1.05–1.47) and AD with cerebrovascular disease (hazard ratio, 1.19; 95% confidence interval, 1.02–1.38). Also, compared with the lowest tertile of estradiol, men in the middle and highest tertile of estradiol had 0.24 and 0.28 points lower Cognitive Abilities Screening Instrument scores, respectively, for each year increase in age.Interpretation:In old men, endogenous testosterone levels are not associated with risk for cognitive decline and AD, whereas higher estrogen levels increase risk for cognitive decline and AD. Ann Neurol 2006.
The safety of breast‐conserving surgery in patients who achieve a complete pathologic response after neoadjuvant chemotherapy
Authors: Peintinger Florentia , Symmans W. Fraser , Gonzalez‐Angulo Ana M. , Boughey Judy C. , Buzdar Aman U. , Yu T. Kuan , Hunt Kelly K. , Singletary S. Eva , Babiera Gildy V. , Lucci Anthony , Meric‐Bernstam Funda , Kuerer Henry M. 
Published: July 2006

AbstractBACKGROUND.The objectives of this study were to determine the locoregional recurrence (LRR) rate and to evaluate the correlation between surgical resection volume (RV) and LRR in patients with breast cancer who underwent segmental mastectomy after achieving a pathologic complete response (pCR) on neoadjuvant chemotherapy.METHODS.The authors reviewed the outcomes of all 109 patients who underwent segmental mastectomy after the complete eradication of invasive disease by neoadjuvant chemotherapy at their institution between 1987 and 2002. LRRs were recorded, and RVs after segmental mastectomy were calculated and categorized as small, medium, or large.RESULTS.At a median follow‐up of 6.6 years, 3 patients (2.7%) developed LRR. In 2 of those patients, the recurrence was located in the ipsilateral breast; in the other patient, the recurrence was located in the supraclavicular lymph nodes with synchronous distant metastases. The median RV was 73.12 cm3 (range, 2.82–451.51 cm3). Large RVs (>125 cm3) were less common than small RVs (up to 70 cm3) or medium RVs (between 70 cm3 and 125 cm3; P = .009 and P<.0001, respectively). One patient with a small RV had an LRR at 4 years, and 2 patients with medium RVs had LLRs at 2.3 years and 6 years, respectively. The 5‐year and 10‐year LRR‐free survival rates were 98.1% and 96.5%, respectively, and the corresponding overall survival rates were 96% and 92%, respectively.CONCLUSIONS.Segmental mastectomy was associated with excellent locoregional control in patients who achieved a pCR after neoadjuvant chemotherapy. Prospective studies are needed to examine whether decreasing the RVs in this patient population leads to an increased LRR rate. Cancer 2006. © 2006 American Cancer Society.
Technologies for olive mill wastewater (OMW) treatment: a review
Authors: Paraskeva Panagiota , Diamadopoulos Evan 
Published: July 2006

AbstractOlive mill wastewater (OMW) arises from the production of olive oil in olive mills. It is produced seasonally by a large number of small olive mills scattered throughout the olive oil‐producing countries. OMW has a very high organic load, recalcitrant in nature and with a high amount of toxicity/phytotoxicity‐associated compounds. Several physicochemical, biological and combined processes have been examined for the treatment of OMW, resulting in considerable organic load and toxicity abatement. Biological processes, aerobic and anaerobic, including anaerobic co‐digestion with other effluents and composting, are predominant in the treatment of OMW. Advanced oxidation processes have attracted much attention owing to the strong oxidation potential of the agents used, which can result in a high degree of treatment. Recent research studies employing physical, chemical, biological and combined technologies are reviewed in the current work. Copyright © 2006 Society of Chemical Industry
Islamic and Christian inspired relief NGOs: between tactical collaboration and strategic diffidence?
Authors: Benedetti Carlo 
Published: July 2006

AbstractThis article focuses on the identification of different types of Islamic and Christian inspired relief NGOs. Four ideal types are outlined following a framework for the analysis of Religious NGOs. The possibilities of collaboration between these NGOs are investigated. The article argues that there is a greater likelihood of collaboration among NGOs closer to the moderate end of the framework. However, collaboration remains difficult on a strategic level and is often limited to a field based, tactical level cooperation. A broader mutual understanding is needed in order to improve global coordination between NGOs coming from different religious traditions. Copyright © 2006 John Wiley & Sons, Ltd.
Induction of P53, P21Waf1, orinithine decorboxylase activity, and DNA damage leading to cell‐cycle arrest and apoptosis following topical application of repeated fish fried oil extract to mice
Authors: Pandey Manoj K. , Dhawan Alok , Das Mukul 
Published: July 2006

AbstractRepeated frying of food produces numerous carcinogens including polycyclic aromatic hydrocarbons (PAHs). Our prior studies have shown that repeated fish fried oil extract (RFFE) induces cytochrome P (CYP)‐450 1A1/2 isozymes thereby causing increased generation of electrophilic reactive metabolites of PAHs and subsequent binding to DNA. In the present study, molecular events associated with DNA damage, apoptosis, and proliferation following topical exposure to RFFE have been investigated in mice. Single topical application of RFFE (500 µg) for 24–48 h caused significant DNA damage with Comet assay in terms of olive tail moment (OTM) (204–246%), tail DNA (253–293%), and tail length (172–195%). Overexpression of p53 and p21WAF1 proteins was observed in skin cells following single topical exposure of RFFE for 24–72 h, which was similar to that of benzo(a)pyrene (BP) exposure (24 h). Though RFFE and BP exposure separately, did not result in G0/G1 arrest, but a significant increase in the proportion of cells in S‐phase was observed. Apoptotic induction was noticed in skin cells, with maximum induction after 48 h of exposure to RFFE. Further, topical treatment of mice with RFFE (500 µg) for 6 h significantly increased orinithine decarboxylase (ODC) activity by 7.5‐fold when compared to control. These results indicate that RFFE exposure caused ODC induction accompanied by increased levels of p53 and p21WAF1 proteins leading of apoptosis and delay of cells in S‐phase thereby indicating the possible carcinogenic potential of RFFE. © 2006 Wiley‐Liss, Inc.
The determination of high‐affinity protein/inhibitor binding constants by electrospray ionization hydrogen/deuterium exchange mass spectrometry
Authors: Frego Lee , Gautschi Elda , Martin Leslie , Davidson Walter 
Published: July 2006

AbstractRecently, a hydrogen/deuterium exchange method termed SUPREX (Stability of Unpurified Proteins from Rates of hydrogen/deuterium EXchange), capable of measuring protein/ligand binding constants, which utilizes matrix‐assisted laser desorption/ionization mass spectrometry (MALDI‐MS), has been reported. Unlike more conventional approaches, SUPREX is inherently capable of measuring Kd values of tight binding ligands. Here we present a SUPREX‐based method, incorporating automation and electrospray ionization (ESI)‐MS, to measure Kd values for very potent inhibitors of the kinase PKCθ. The use of ESI offers an alternative to MALDI, with the advantages of improved mass measurement precision for larger proteins, and amenability to automation. Kd values generated by this method are in good agreement with those generated by a molecular protein kinase assay. Copyright © 2006 John Wiley & Sons, Ltd.
Prenatal diagnosis of a possible new middle interhemispheric variant of holoprosencephaly using sonographic and magnetic resonance imaging
Authors: Picone O. , Hirt R. , Suarez B. , Coulomb A. , Tachdjian G. , Frydman R. , Senat M.‐V. 
Published: July 2006

AbstractA peculiar subtype of holoprosencephaly, middle interhemispheric variant (MIH), which is characterized by a partial posterior interhemispheric fusion of the brain, has been described in children. We describe the features of a case of a possible new MIH at 26 weeks of gestation, diagnosed using prenatal sonography and magnetic resonance imaging and confirmed by postmortem examination. This malformation of the brain was associated with an unusual appearance of the corpus callosum and rare chromosomal abnormality: a 45X/46,XX/47,XX,+ 18 mosaicism. Copyright © 2006 ISUOG. Published by John Wiley & Sons, Ltd.
LAKER: learning from past actions to guide future behaviors in ad hoc routing
Authors: Li Jian , Mohapatra Prasant 
Published: July 2006

AbstractIn this paper, we present a location aided knowledge extraction routing (LAKER) protocol for mobile ad hoc networks (MANETs). The novelty of LAKER is that it learns from past actions to guide future behaviors. In particular, LAKER cangradually discovercurrent topological characteristics of the network, such as population density distribution, residual battery map, and traffic load status. This knowledge can be organized in the form of a set ofguiding routes, each of which consists of a chain of guiding positions between a pair of source and destination locations. The guiding route information is learned by individual nodes during route discovery phase, and it can be used to guide future route discovery processes in a more efficient manner. LAKER is especially suitable for mobility models where nodes are not uniformly distributed. LAKER can exploit topological characteristics in these models and limit the search space in route discovery processes in a more refined granularity than location aided routing (LAR) protocol. Simulation results show that LAKER outperforms LAR and DSR in term of routing overhead, saving up to 30–45% broadcast routing messages compared to LAR approach. Copyright © 2006 John Wiley & Sons, Ltd.
Tolstoy’s Report of Five Cases of Chest Trauma: Its Relevance to Contemporary Military Surgical Experience
Authors: Molnar Tamas F. , Lukacs Laszlo 
Published: July 2006

AbstractFragments of the history of trauma care, an important part of our surgical heritage, can offer a relevant message to contemporary science, even at the level of statistical evaluations. A surprisingly good match of results using two distinctively different approaches for calculating survival after a chest injury is reported in a historical model. Statistical data published by French and British surgeons serving in the Crimean War (1853–1856) were found to conform with the analysis of literary observations in Leo Tolstoy’s Sebastopol Sketches. The nearly complete agreement on survival probabilities from two sources so different in their nature highlights the question of the relevance of nonstatistical methods in other fields of surgery as well.
Phyllodes Tumor of the Breast: The Challenge Persists
Authors: Cheng Shih‐Ping , Chang Yuan‐Ching , Liu Tsang‐Pai , Lee Jie‐Jen , Tzen Chi‐Yuan , Liu Chien‐Liang 
Published: July 2006

AbstractIntroductionPhyllodes tumors of the breast are uncommon, and it is difficult to predict biologic behavior based on clinicopathologic features. Despite the wealth of data on the factors to predict recurrence, little is known about the impact of treatment refinements. This study seeks to define changes in patient characteristics, histopathologic parameters, and outcome between the two periods before and after the care of patients with breast diseases was centralized to a breast specialty.MethodsThe records of 182 patients with phyllodes tumors managed surgically were reviewed. Patients treated from 1985 to 1996 (n = 81) were compared with those seen from 1997 to 2004 (n = 101).ResultsThe analysis of the two treatment periods revealed that there was a decrease in tumor size at diagnosis, from 7.7 cm during the earlier period to 4.6 cm during the recent period (P= 0.003). The patients undergoing breast‐conserving surgery were significantly increased during the recent period. In contrast, pathologic features and local recurrence rates remained unchanged during the study period. Multivariate analysis revealed that positive surgical margin was the only independent predictor of recurrence, with an increased hazard of 8.0. Overall, upgrading to the next grade was observed in 16% of recurrences.ConclusionsBreast‐conserving surgery with clear margins is the current treatment of choice for phyllodes tumors, but this strategy does not further reduce local recurrence effectively. Optimal management continues to be a challenge.