bluuebunny/crossref_metadata_2025_split huggingface dataset:
Deep learning–based quantification of total bleeding volume and its association with complications, disability, and death in patients with aneurysmal subarachnoid hemorrhage
Authors: Hu Ping , Wu Yanze , Yan Tengfeng , Shu Lei , Liu Feng , Xiao Bing , Ye Minhua , Wu Miaojing , Lv Shigang , Zhu Xingen 
Published: April 2024

OBJECTIVE
The relationships between immediate bleeding severity, postoperative complications, and long-term functional outcomes in patients with aneurysmal subarachnoid hemorrhage (aSAH) remain uncertain. Here, the authors apply their recently developed automated deep learning technique to quantify total bleeding volume (TBV) in patients with aSAH and investigate associations between quantitative TBV and secondary complications, adverse long-term functional outcomes, and death.

METHODS
Electronic health record data were extracted for adult patients admitted to a single institution within 72 hours of aSAH onset between 2018 and 2021. An automatic deep learning model was used to fully segment and quantify TBV on admission noncontrast head CT images. Patients were subgrouped by TBV quartile, and multivariable logistic regression, restricted cubic splines, and subgroup analysis were used to explore the relationships between TBV and each clinical outcome.

RESULTS
A total of 819 patients were included in the study. Sixty-six (8.1%) patients developed hydrocephalus, while 43 (5.3%) experienced rebleeding, 141 (17.2%) had delayed cerebral ischemia, 88 (10.7%) died in the 12 months after discharge, and 208 (25.7%) had a modified Rankin Scale score ≥ 3 12 months after discharge. On multivariable analysis, patients in the highest TBV quartile (> 37.94 ml) had an increased risk of hydrocephalus (adjusted OR [aOR] 4.38, 95% CI 1.61–11.87; p = 0.004), rebleeding (aOR 3.26, 95% CI 1.03–10.33; p = 0.045), death (aOR 6.92, 95% CI 1.89–25.37; p = 0.004), and 12-month disability (aOR 3.30, 95% CI 1.62–6.72; p = 0.001) compared with the lowest TBV quantile (< 8.34 ml). The risks of hydrocephalus (nonlinear, p = 0.025), rebleeding, death, and disability (linear, p > 0.05) were positively associated with TBV by restricted cubic splines. In subgroup analysis, TBV had a stronger effect on 12-month outcome in female than male patients (p for interaction = 0.0499) and on rebleeding prevalence in patients with endovascular coiling than those with surgical clipping (p for interaction = 0.008).

CONCLUSIONS
Elevated TBV is associated with a greater risk of hydrocephalus, rebleeding, death, and poor prognosis.
Adaptive, behavioral, and emotional outcomes following postoperative pediatric cerebellar mutism syndrome in survivors treated for medulloblastoma
Authors: Raghubar Kimberly P. , Heitzer Andrew M. , Malbari Fatema , Gill Jason , Sillitoe Roy V. , Merrill Livia , Escalante Johanna , Okcu M. Fatih , Aldave Guillermo , Meoded Avner , Kralik Stephen , Davis Kimberly , Ma Marina , Warren Emily A. H. , McCurdy Mark D. , Weiner Howard L. , Whitehead William , Scheurer Michael E. , Rodriguez Lisa , Daigle Amy , Chintagumpala Murali , Kahalley Lisa S. 
Published: April 2024

OBJECTIVE
Patients who experience postoperative pediatric cerebellar mutism syndrome (CMS) during treatment for medulloblastoma have long-term deficits in neurocognitive functioning; however, the consequences on functional or adaptive outcomes are unknown. The purpose of the present study was to compare adaptive, behavioral, and emotional functioning between survivors with and those without a history of CMS.

METHODS
The authors examined outcomes in 45 survivors (15 with CMS and 30 without CMS). Comprehensive neuropsychological evaluations, which included parent-report measures of adaptive, behavioral, and emotional functioning, were completed at a median of 2.90 years following craniospinal irradiation.

RESULTS
Adaptive functioning was significantly worse in the CMS group for practical and general adaptive skills compared with the group without CMS. Rates of impairment in practical, conceptual, and general adaptive skills in the CMS group exceeded expected rates in the general population. Despite having lower overall intellectual functioning, working memory, and processing speed, IQ and related cognitive processes were uncorrelated with adaptive outcomes in the CMS group. No significant group differences or increased rates of impairment were observed for behavioral and emotional outcomes.

CONCLUSIONS
Survivors with CMS, compared with those without CMS, are rated as having significant deficits in overall or general adaptive functioning, with specific weakness in practical skills several years posttreatment. Findings from this study demonstrate the high risk for ongoing functional deficits despite acute recovery from symptoms of CMS, highlighting the need for intervention to mitigate such risk.
Shunt timing in low-weight infants in the treatment of hydrocephalus
Authors: Chiarelli Peter A. , Chapman Nicholas , Flyer Benjamin E. , Chu Jason K. , Krieger Mark D. 
Published: April 2024

OBJECTIVE
The optimal timing of ventricular shunt placement in low-weight and preterm infants remains an unresolved topic in modern pediatric neurosurgery. Shunt placement for hydrocephalus is performed over a wide range of infant weights, and the standard weight threshold for shunt placement can vary substantially across institutions. The aim of this study was to investigate shunt outcome in infants of low body weight.

METHODS
An IRB-approved retrospective analysis of 76 infants (29 females, 47 males) who received primary shunt placement between 2003 and 2018 was performed. Uniform criteria were used over the entire dataset to determine the safety for ventriculoperitoneal (VP) shunt placement: 1) weight near or above 1500 g, 2) feeding tolerance, and 3) lack of necrotizing enterocolitis or active systemic infection. Infants were classified into a low-weight (LW) (< 2000 g) or standard weight (SW) (2000–3000 g) group based on their body weight at the time of initial shunt placement. Shunt survival was compared between the groups. The threshold weight separating the LW and SW groups and outcomes was additionally varied and systematically reanalyzed.

RESULTS
Shunts were placed in 24 LW infants and 52 SW infants over the inclusion period. Etiologies for hydrocephalus were similar across groups: predominantly intraventricular hemorrhage (54%) (p = 0.13) and open neural tube defect (29%) (p = 0.61). Both LW and SW groups had 58% 1-year shunt survival rates. Overall, 46% of shunts failed in the LW group compared with 54% in the SW group over a median follow-up of 47 months (range 0–170 months). A log-rank test comparing shunt survival rates did not show significance (p = 0.43). Groups were repartitioned using a range of threshold weights (1600–2400 g) to divide LW from SW infants. The lack of association between VP shunt placement in LW infants and time frame of revision was consistently observed over the full range of varied threshold weights.

CONCLUSIONS
There was no significant difference in overall time to shunt revision between infants weighing < 2000 g and infants weighing 2000–3000 g. No correlation between weight and shunt survival was detected. Combined with other clinical features pertinent to the management of hydrocephalus in the neonatal population, this investigation provides insight toward clinical decision-making regarding infants of low birth weight and suggests that further multi-institutional study on this topic is warranted.
Development and validation of an artificial intelligence model to accurately predict spinopelvic parameters
Authors: Harake Edward S. , Linzey Joseph R. , Jiang Cheng , Joshi Rushikesh S. , Zaki Mark M. , Jones Jaes C. , Khalsa Siri Sahib S. , Lee John H. , Wilseck Zachary , Joseph Jacob R. , Hollon Todd C. , Park Paul 
Published: April 2024

OBJECTIVE
Achieving appropriate spinopelvic alignment has been shown to be associated with improved clinical symptoms. However, measurement of spinopelvic radiographic parameters is time-intensive and interobserver reliability is a concern. Automated measurement tools have the promise of rapid and consistent measurements, but existing tools are still limited to some degree by manual user-entry requirements. This study presents a novel artificial intelligence (AI) tool called SpinePose that automatically predicts spinopelvic parameters with high accuracy without the need for manual entry.

METHODS
SpinePose was trained and validated on 761 sagittal whole-spine radiographs to predict the sagittal vertical axis (SVA), pelvic tilt (PT), pelvic incidence (PI), sacral slope (SS), lumbar lordosis (LL), T1 pelvic angle (T1PA), and L1 pelvic angle (L1PA). A separate test set of 40 radiographs was labeled by four reviewers, including fellowship-trained spine surgeons and a fellowship-trained radiologist with neuroradiology subspecialty certification. Median errors relative to the most senior reviewer were calculated to determine model accuracy on test images. Intraclass correlation coefficients (ICCs) were used to assess interrater reliability.

RESULTS
SpinePose exhibited the following median (interquartile range) parameter errors: SVA 2.2 mm (2.3 mm) (p = 0.93), PT 1.3° (1.2°) (p = 0.48), SS 1.7° (2.2°) (p = 0.64), PI 2.2° (2.1°) (p = 0.24), LL 2.6° (4.0°) (p = 0.89), T1PA 1.1° (0.9°) (p = 0.42), and L1PA 1.4° (1.6°) (p = 0.49). Model predictions also exhibited excellent reliability at all parameters (ICC 0.91–1.0).

CONCLUSIONS
SpinePose accurately predicted spinopelvic parameters with excellent reliability comparable to that of fellowship-trained spine surgeons and neuroradiologists. Utilization of predictive AI tools in spinal imaging can substantially aid in patient selection and surgical planning.
New in the normative regulation of peer-reviewed scientific publications of the Higher Attestation Commission of the Ministry of Science and Higher Education of the Russian Federation on the example of journals on theology
Authors: Макаров Денис Владимирович 
Published: April 2024

Цель исследования — анализ основных изменений, регулирующих деятельность рецензируемых научных изданий, в которых должны быть опубликованы основные научные результаты диссертаций на соискание ученой степени кандидата наук, на соискание ученой степени доктора наук. Актуальность работы определяется, с одной стороны, необходимостью решения проблем перерегистрации научных журналов по новым шифрам научных специальностей и последующего их распределения по категориям. С другой стороны, актуальность связана с практическим приложением результатов работы для выбора аспирантами и соискателями, а также преподавателями высших духовных учебных заведений тех или иных журналов для публикации в зависимости от стоящих перед ними научных целей.
The purpose of the study is to analyze the main changes that regulate the activities of peer-reviewed scientific publications, in which the main scientific results of dissertations for the degree of candidate of science, for the degree of doctor of science should be published. The relevance of the work is determined, on the one hand, by the need to solve the problems of re-registration of scientific journals according to new codes of scientific specialties and their subsequent distribution into categories. On the other hand, the relevance is associated with the practical application of the results of the work for the choice of graduate students and applicants, as well as teachers of higher theological educational institutions of certain journals for publication, depending on their scientific goals.
Labor relations in theological educational institutions
Authors: Семенова Наталия Сергеевна 
Published: April 2024

Духовные учебные заведения, именуемые в светском законодательстве духовными образовательными организациями, имеют особый правовой статус, являясь религиозными и образовательными организациями одновременно. При этом, статус религиозной организации первичен. Поскольку правовое регулирование деятельности религиозных организаций, как и сферы образовательных отношений, имеет свою специфику, то в статье сначала рассматриваются общие особенности трудовых отношений в религиозных организациях, а затем применительно к духовным образовательных организациям с учетом особенностей трудовых отношений в сфере высшего образования. Отдельный раздел посвящен заключению трудовых договоров как в религиозных организациях вообще, так и в духовных образовательных организациях, в частности, на примере духовных учебных заведений Русской Православной Церкви. В статье также рассматриваются общие требования к духовным образовательным организациям, как работодателям, и к членам профессорско-преподавательского состава, как работникам, в том числе в свете необходимости прохождения государственной аккредитации.
The status of a religious organization is primary. Since the legal regulation of the activities of religious organizations, as well as the sphere of educational relations, has its own specifics, the article first discusses the general features of labor relations in religious organizations, and then in relation to theological educational organizations, taking into account the specifics of labor relations in the field of higher education. A separate section is devoted to the conclusion of labor contracts both in religious organizations in general and in theological educational organizations, in particular, on the example of theological educational institutions of the Russian Orthodox Church. The article also discusses the general requirements for theological educational organizations, as employers, and for members of the teaching staff, as employees, including in the light of the need to undergo state accreditation.
ВПЛИВ ПОРУШЕННЯ РОТАТОРНОЇ МАНЖЕТИ ПЛЕЧА НА ПОСТАВУ ЛЮДИНИ
Authors: ВАВДІЮК Ганна , СТРУБІЦЬКА Наталія , АНДРІЙЧУК Ольга , РУДЕНКО Анна 
Published: April 2024

Дослідження у сфері медицини виявило, що порушення ротаторної манжети плеча є поширеною проблемою, що часто виникає внаслідок травми, перенапруження або дегенеративних змін. Результати показали, що цей стан може значно впливати на поставу людини та спосіб її рухів. Дослідження також виявило зв'язок між порушенням ротаторної манжети та поставою людини, зокрема, учасники з аномальною поставою мали більшу ймовірність мати розриви м'язів ротаторної манжети. Враховуючи ці результати, важливо розуміти взаємозв'язок між станом плечового суглоба та поставою для ефективного діагнозу та лікування захворювань цієї області.
У цій статті систематично проаналізовано вплив порушення ротаторної манжети плеча на різні аспекти фізіології та функціонування людини під час ходьби. Виявлено, що порушення ротаторної манжети може значно обмежувати рухову активність в плечовому суглобі, що в свою чергу впливає на спосіб, як людина виконує рухи рук та верхньої частини тулуба під час ходьби. Крім того, відчуття болю або дискомфорту у плечі може призводити до змін у механіці руху та ходьби, оскільки людина намагається уникнути дискомфорту, що може призводити до нерівномірного навантаження на м'язи та суглоби під час ходьби.
Додатково, порушення ротаторної манжети може також впливати на поставу людини під час ходьби, змушуючи її випереджати тіло вперед або змінювати свою позу, щоб зменшити навантаження на травмовану область плеча. Ці зміни в поставі можуть впливати на загальну механіку ходьби, а також можуть призводити до втрати стабільності плеча та змін у балансі тіла. Такий вплив порушень ротаторної манжети підкреслює важливість розуміння цього аспекту для ефективного діагнозу та лікування захворювань плечового суглоба та підтримки оптимальної функціональності людини під час ходьби.
У дослідженні описано вплив різних положень тулуба на кінематику м'язів лопатки під час зовнішньої ротації плеча. Результати показали, що зміни в положенні тулуба значно впливають на кут нахилу лопатки та зовнішню ротацію плеча. У положенні згинання-розгинання тулуба спостерігалося зменшення зовнішньої ротації плеча, але збільшення активності м'язів лопатки. Ці результати підкреслюють важливість правильного положення тулуба для оптимального функціонування м'язів лопатки та механіки руху плеча. У додаток до цього, інше дослідження показало важливий вплив положення тіла під час сидіння на провокацію болю та рівень болю під час клінічних тестів на плече у пацієнтів з плечевими проблемами.
Spirulina platensis: A comprehensive review of its nutritional value, antioxidant activity and functional food potential
Authors: Sahil Siramdas , Bodh Suman , Verma Praveen 
Published: April 2024

BACKGROUND: Spirulina platensis is a well-known photosynthetic prokaryotic alga that has gained recognition in various industries, including food, health, aquaculture and pharmaceuticals. The United Nations acknowledged spirulina as a nutritious food source because of its rich pigments and high protein content. OBJECTIVE: This paper aims to provide an overview of how Spirulina is utilized as both a dietary supplement as well as functional food ingredient in the food industry. METHOD: Spirulina powder can be added to various foods such as bread, cakes and cookies to increase the nutritional value. It is particularly valuable as a dietary supplement in efforts to combat malnutrition in impoverished regions. RESULT: Spirulina platensis is also a source of essential components used in the therapeutic microalgae supplement market. These components include alpha-carotene, astaxanthin, polyunsaturated fatty acids (such as DHA and EPA) and polysaccharides like beta-glucan. CONCLUSION: It is evident that the consumption of spirulina algae can offer both financial benefits and health advantages. Even though there is a large amount of research on the nutritional, environmental and social benefits of spirulina, some natural areas still produce insufficient amounts of the algae. As a result, more and more scientists and researchers throughout the world are pushing for the growth of spirulina farming.
Multiple Mnazi Mmoja
Authors: Saidi Finzi , Makhubu Jabulani Absalom , Adu-Agyei Dickson 
Published: April 2024

This paper argues for the appreciation of multiple identities present within cities in Africa by discussing the pedagogic experiment of an architectural design studio and the design projects of the studio between 2017 and 2019. Mnazi Mmoja is a Kiswahili phrase loosely translated to mean "one coconut tree"- oneness in a post-colonial context. This paper interrogates the problematic single-stroke description of African challenges, a continent with over 51 countries with diverse cultures, ethnicities, and urban morphologies. The paper argues that there are many Mnazi Mmoja. Unit15X’s design teaching strategy has been to challenge knowledge in architecture, landscape, and urban design by First taking students at the University of Johannesburg to other African countries to foster cultural awareness. Secondly, Unit15X’s studio utilizes landscape themes, allowing students to research complex relationships between urban inhabitants and their landscapes and their production to enhance critical awareness and move beyond aesthetic explorations. Our curiosity guides us to understand what it means to practice architecture, landscape architecture, urban design, and planning by interrogating public spaces on the continent. This paper discusses Unit15X's studio exploration of Larval (Emergent) Landscapes on the public space of the Mnazi Moja site of historical and cultural significance in Dar es Salaam in Tanzania through two students' speculative design projects.Two students’ projects, The Anti-Atlas, and The One Coconut Tree, explore the concept of Mnazi Mmoja- 'oneness' - to pause questions that challenge planning and design legislations and begin to speculate on how indigenous knowledge, multiple identities, and African material conditions can be (re)-applied to contemporary contexts in order to raise awareness of: identity; multiculturalism in cites; post-colonial urbanism within cities in an attempt to reinterpret the multiple representations of the concept of Mnazi Mmoja.
Shape and Height of Human Duodenal Villi
Authors: Sayeed Sharmina , Ara Shamim , Reza Rumana , Rahman Sadia , Kashem Kanetarin , Paul Uttam Kumar 
Published: April 2024

Context: Villus atrophy of the small intestine is one of the causes of chronic diarrhoea. The etiology of villus atrophy of the small intestine includes celiac disease, tropical sprue, Giardiasis etc. The knowledge of villus shape and height of duodenum in Bangladeshi people can help the gastroenterologist to diagnosis and provide better treatment.
Materials & Methods: A Cross sectional, analytical type of study was performed in the Department of Anatomy of Dhaka Medical College, Dhaka from July 2010 to June 2011 on histological slides of 19 human duodenums of Bangladeshi people. The sample was divided into 5 different age groups, group A (20-29 years), group B (30-39 years), group C (40-49 years), group D (50-59 years) and group E (60-69 years). From group A, B and C five duodenums and from group D and E two duodenums were stained with Harris’ Haematoxylin and Eosin stains. From each four parts of duodenum four paraffin blocks were prepared and best 76 slides were taken. The shape of villi in each four parts of the duodenum was observed and noted. The height of villi was measured by using a stage micrometer and ocular micrometer.
Results: The shape of the villi were broader & shorter in age group E (60-69 years). Villi were found finger sharped in all age groups. The mean difference in height of villi in different parts of duodenum between group A and B, group B and C, group B and D, group C and D, group C and E, group D and E were statistically not significant. But the difference between height of villi of the first part of the duodenum in group A and C, group A and D, group A and E, group B and E found statistically significant (p< 0.05) and the difference between height of villi of fourth part of the duodenum in group A and C, group A and D, group A and E found statistically significant (p < 0.05).­­­
Bangladesh J. Anat. 2015; 13(1) : 1-7
PENYUSUNAN STANDAR PELAYANAN PADA DINAS PENANAMAN MODAL DAN PELAYANAN TERPADU SATU PINTU (DPMPTSP) KABUPATEN TAKALAR
Authors: Sayuti Nuraeni , Nasir Abd Wahid 
Published: April 2024

Setiap negara yang ada di dunia memiliki kewajiban untuk memberikan layanan kepada masyarakatnya. Terkhusus Negara Indonesia yang memiliki luas wilayah berbentuk kepulauan menyebabkan masyarakat yang tersebar luas. Negara Indonesia memperkenalkan otonomi daerah untuk memenuhi semua kebutuhan dasar. Hal ini merupakan hak setiap warga negara untuk melaksanakan pelayanan administrasi yang diperoleh dari pemerintah sebagai penyedia pelayanan publik. Instansi Pemerintah Daerah merupakan instansi dengan tingkat keluhan terbanyak di Indonesia dan terkhusus di Sulawesi Selatan menduduki posisi keempat sebagai provinsi dengan keluhan pelayanan terbanyak. DPMPTS Kabupaten Takalar yang telah menduduki zona kuning dalam pelayanan masih menghadapi beberapa hambatan dalam pelayanan publik seperti belum adanya prosedur layanan yang dipublikasi dalam standar pelayanan sehingga perlu dilakukan pengembangan dalam standar pelayanannya. Penelitian ini menggunakan teknik wawancara, observasi dan telaah dokumen. Hasil akhir dari penelitian ini yakni standar pelayanan yang disusun berdasarkan pedoman penyusunan standar pelayanan dari PERMENPAN RB nomor 15 tahun 2014. Karya ini merupakan solusi untuk mengatasi permasalahan yang muncul.