bluuebunny/crossref_metadata_2025_split huggingface dataset:
Recent corticosteroid use and recent disease activity: Independent determinants of coronary heart disease risk factors in systemic lupus erythematosus?
Authors: Karp Igor , Abrahamowicz Michal , Fortin Paul R. , Pilote Louise , Neville Carolyn , Pineau Christian A. , Esdaile John M. 
Published: January 2008

AbstractObjectiveSystemic lupus erythematosus (SLE) is characterized by a markedly elevated risk for coronary heart disease (CHD), the exact pathogenesis of which is unknown. In particular, the causal roles of corticosteroid therapy and SLE disease activity, and whether their putative effects are mediated through conventional risk factors, remain unclear.MethodsData abstracted retrospectively from the charts at 11,359 clinic visits for 310 patients with SLE to the Montreal General Hospital were used to investigate the associations of recent corticosteroid dose and recent Systemic Lupus Erythematosus Disease Activity Index (SLEDAI) score with 8 CHD risk factors (total serum cholesterol, high‐density lipoprotein [HDL] cholesterol, low‐density lipoprotein cholesterol, apolipoprotein B [Apo B], triglycerides, systolic blood pressure [BP], body mass index, and blood glucose) and the aggregate estimate of 2‐year CHD risk. Separate multivariable linear regression models estimated the mutually‐adjusted effects of average daily corticosteroid dose and average SLEDAI score within the past year on the current level of each risk factor while adjusting for age, sex, cumulative damage score, disease duration, and, where appropriate, use of relevant medications.ResultsHigher past‐year corticosteroid dose was independently associated with significantly higher overall 2‐year CHD risk and with higher levels of all 8 individual risk factors. Higher past‐year lupus disease activity was independently associated with higher overall 2‐year CHD risk, lower HDL cholesterol, and higher values of systolic BP, Apo B, triglycerides, and blood glucose.ConclusionIn SLE, both recent use of corticosteroids and recent lupus activity are independently associated with higher values of several well‐recognized CHD risk factors and overall 2‐year CHD risk.
Enhanced systemic availability of methotrexate in the presence of morin in rats
Authors: Hong Soon Sun , Jin Ming‐Ji , Han Hyo‐Kyung 
Published: January 2008

AbstractThe present study aimed to investigate the effect of morin on the pharmacokinetics of methotrexate (MTX) in rats. Pharmacokinetic parameters of MTX were determined in rats following an intravenous administration of MTX (2 mg/kg) in the presence and absence of morin (25 mg/kg, p.o.). The cellular accumulation of MTX was also examined by using MDCK cells stably overexpressing hOAT1 or hOAT3. Compared with the control given MTX alone, pretreatment with morin 15 min prior to MTX administration significantly altered the pharmacokinetics of MTX in rats. Renal clearance and total clearance of MTX were reduced by 42% and 58%, respectively, in the presence of morin. Accordingly, the systemic exposure of MTX in the rats pretreated with morin was significantly higher than that from the control group. The mean residence time (MRT) and terminal plasma half‐life of MTX were prolonged by 3.3‐ and 2.4‐fold, respectively, by the concurrent use of morin. The cellular uptake of MTX (20 µM) was significantly reduced by the co‐incubation with morin (100 µM) in MDCK‐hOAT1 cells but not in MDCK‐hOAT3 cells. Taken together, morin appeared to be effective in altering the pharmacokinetics of MTX in rats, likely by the inhibition of OAT1‐mediated renal excretion. Copyright © 2008 John Wiley & Sons, Ltd.
Future‐biased search: the quest for the ideal
Authors: Shu Suzanne B. 
Published: February 2008

AbstractDecision‐makers with ideal candidates already in mind often extend search beyond optimal endpoints when searching for the best option among a sequential list of alternatives. Extended search is investigated here using three laboratory experiments; individuals in these tasks exhibit future‐bias, delaying choice beyond normative benchmarks. Searchers' behavior is consistent with setting high thresholds based on a focal ideal outcome without full attention to its probability or the value of second‐best alternatives; the behavior is partially debiased by manipulating which outcomes are in the searchers' focal set. Documenting future‐bias in sequential search tasks offers new insights for understanding self‐control and intertemporal choice by providing a situation in which thresholds may be set too high and myopic behavior does not prevail. Copyright © 2008 John Wiley & Sons, Ltd.
Antioxidant and free radical scavenging activities of an exopolysaccharide from a probiotic bacterium
Authors: Kodali Vidya Prabhakar , Sen Ramkrishna 
Published: February 2008

AbstractProbiotic bacteria synthesize extracellular polysaccharides (EPSs) with commercially significant physiological and therapeutic activities. This important class of biomolecules is also characterized by their ability to remove reactive oxygen species (ROS) that are formed in the intestine by various metabolic reactions; hence, they exhibit antioxidant activities. Our probiotic bacterium, Bacillus coagulans RK‐02, produces an EPS during the exponential and stationary growth phases when grown in a glucose mineral salts medium. The time course of EPS synthesis was studied with respect to biomass growth. The antioxidant and free radical scavenging potential of isolated EPS were studied by various methods, including the β‐carotene‐linoleic acid model system, a superoxide radical scavenging assay using the PMS‐NADH‐nitroblue tetrazolium system, the 1,1‐diphenyl‐2‐picrylhydrazyl radical scavenging activity, a hydroxyl radical scavenging assay using the ascorbic acid‐Cu2+‐cytochrome c system and an in vitro microsome peroxidation inhibition study using a thiobarbituric acid assay. The antioxidant activities were compared to known antioxidants vitamin C and E, which were used as reference standards. The results showed that the EPS, which is a heteropolymer composed of four monosaccharides, produced by B. coagulans RK‐02 had significant antioxidant and free radical scavenging activities.
Monitoring of native chemical ligation on solid substrate by surface plasmon resonance
Authors: Wieczerzak Ewa , Hamel Raymond , Chabot Vincent , Aimez Vincent , Grandbois Michel , Charette Paul G. , Escher Emanuel 
Published: January 2008

AbstractDuring the last years native chemical ligation (NCL) gained in popularity as a method allowing the chemical synthesis of large peptides and entire proteins. NCL is particularly well‐suited for chemoselective and nondenaturing attachment of biomolecules on solid substrates. In the present work, we show the feasibility of monitoring of peptide synthesis, NCL and its catalysis on silicon oxide modified gold surfaces by surface plasmon resonance (SPR). NCL of a model peptide—bradykinin thioester—was carried out and monitored with a custom‐built SPR apparatus. Solid‐phase produced bradykinin thioester was ligated to the surface in the presence of variable concentrations of 4‐mercaptophenylacetic acid as transthioesterification catalyst. At catalyst concentration of 48 mM and above, the NCL reaction was maximal and identical to the reaction of the purified peptide‐mercaptophenylacetic acid thioester. SPR curves indicate typical first‐order kinetics with t1/2 of 81 s for this aryl thioester, but of 104 min for the primary alkyl thioester. © 2008 Wiley Periodicals, Inc. Biopolymers (Pept Sci) 90: 415–420, 2008.This article was originally published online as an accepted preprint. The “Published Online” date corresponds to the preprint version. You can request a copy of the preprint by emailing the Biopolymers editorial office at biopolymers@wiley.com
A powerful and versatile educational software to simulate transient heat transfer processes in simple fins
Authors: Del Cerro Velázquez F. , Gómez‐Lopera S. A. , Alhama F. 
Published: February 2008

AbstractBased on the network simulation method and using commercial computer codes, educational software has been developed for numerically solving and simulating lineal and non‐lineal problems of unsteady heat transfer in simple extended 1D surfaces, assuming convection and/or radiation as boundary conditions. Interface communication with the user is pleasant and immediate through the window ambient created in visual C++ source code. After introduction of the data, which includes reticulation parameters, a network model is generated whose finite difference differential equations are formally equivalent to those of the problem. Time remains a continuous variable in the model. The file is numerically run using a network simulation code, providing the transient temperature fields and heat fluxes in the whole medium. The results are shown by graphics or as tables. The program can be used as a low cost laboratory tool for teaching heat transfer or even for the design of simple fins. Students can easily determine the influence of physical parameters, such as thermal conductivity, specific heat, heat transfer coefficient, emissivity, reference temperatures, etc., in the problem. © 2008 Wiley Periodicals, Inc. Comput Appl Eng Educ 16: 72–82, 2008; Published online in Wiley InterScience (www.interscience.wiley.com); DOI 10.1002/cae.20159
Combining High Electron Affinity and Intramolecular Charge Transfer in 1,3‐Dithiole–Nitrofluorene Push–Pull Diads
Authors: Perepichka Dmitrii F. , Perepichka Igor F. , Ivasenko Oleksandr , Moore Adrian J. , Bryce Martin R. , Kuz'mina Lyudmila G. , Batsanov Andrei S. , Sokolov Nikolai I. 
Published: January 2008

AbstractAttaching electron‐rich 1,3‐dithiol‐2‐ylidene moieties to polynitrofluorene electron acceptors leads to the formation of highly conjugated compounds 6 to 11, which combine high electron affinity with a pronounced intramolecular charge transfer (ICT) that is manifested as an intense absorption band in their visible spectra. Such a rare combination of optical and electronic properties is beneficial for several applications in optoelectronics. Thus, incorporation of fluorene–dithiole derivative 6 a into photoconductive films affords photothermoplastic storage media with dramatically increased photosensitivity in the ICT region. A wide structural variation of the dithiole and fluorene parts of the molecules reveals excellent correlation between the ICT energy and the reduction potential with the Hammett's parameters for the substituents. Although only a small solvatochromism of the ICT band was observed, heating the solution led to a pronounced blueshift, which was probably as a result of increased twisting around the C9C14 bond that links the fluorene and dithiole moieties. X‐ray crystallographic analysis of 7 a, 8 a, 10 a, 11 a and 13 a confirms an ICT interaction in the ground state of the molecules. The C9C14 double bond between the donor and acceptor is substantially elongated and its length increases as the donor character of the dithiole moiety is enhanced.
ChemInform Abstract: Benchmark Calculations on the Electron Detachment Energies of MO3‐ and M2O6‐ (M: Cr, Mo, W)
Authors: Li Shenggang , Dixon David A. 
Published: January 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: The Crystal Structure of NbO2I — A Double‐Layer Structure with 7‐Coordinated Niobium.
Authors: Hartwig Sabina , Hillebrecht Harald 
Published: January 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Transition Metal‐Centered Trigonal Prisms as Building Units in Ln14M3In3 (Ln: Y, Ho, Er, Tm, Lu; M: Pd, Ir, Pt) and Y4IrIn.
Authors: Zaremba Roman , Rodewald Ute Ch. , Poettgen Rainer 
Published: January 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Structure and Magnetic Properties of CePtZn.
Authors: Mishra Ratikanta , Hermes Wilfried , Poettgen Rainer 
Published: January 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Antimony‐121 Moessbauer Spectral Study of the Eu14MnSb11 and Yb14MnSb11 Zintl Compounds.
Authors: Hermann Raphael P. , Grandjean Fernande , Kafle D. , Brown Dennis E. , Johnson C. E. , Kauzlarich S. M. , Long Gary J. 
Published: January 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis and Characterization of an Aluminogermanate SU‐46 with a Zeolite Structure.
Authors: Shi Lei , Christensen Kirsten E. , Jansson Kjell , Sun Junliang , Zou Xiaodong 
Published: January 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Zeolite‐Like Nitride—Chlorides with a Predicted Topology.
Authors: Barnes Andrew J. D. , Prior Timothy J. , Francesconi M. Grazia 
Published: January 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: A Pure Bismuth A Site Polar Perovskite Synthesized at Ambient Pressure.
Authors: Bridges Craig A. , Allix Mathieu , Suchomel Matthew R. , Kuang Xiaojun , Sterianou Iasmi , Sinclair Derek C. , Rosseinsky Matthew J. 
Published: January 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: A Chain‐Like Polyoxotungstate Constructed from [CeW10O36]9‐, [Na5(H2O)17Cl]4+, and [Na2(H2O)8]2+ Units: (NH4)3[Na5(H2O)17Cl] {[Na(H2O)4]2 [CeW10O36]}×6H2O.
Authors: Yuan Ling , Qin Chao , Wang Xinlong , Wang Enbo 
Published: January 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: New Template‐Free Layered Manganese(III) Phosphate: Hydrothermal Synthesis, ab initio Structural Determination, and Magnetic Properties.
Authors: Ferdov Stanislav , Lopes Armandina M. L. , Lin Zhi , Sa Ferreira Rute A. 
Published: January 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Fast DKR of Amines Using Isopropyl 2‐Methoxyacetate as Acyl Donor.
Authors: Veld Martijn A. J. , Hult Karl , Palmans Anja R. A. , Meijer E. W. 
Published: January 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis of 2‐Oxazolines and 2‐Thiazolines Using Lanthanide Amino Alkoxide.
Authors: Padmavathi V. , Reddy B. Chandra Obula , Thriveni P. , Mohan A. V. Nagendra 
Published: January 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Titanium and Zirconium Complexes with Helical Bis(phenolato) Ligands as Hydroamination Catalysts.
Authors: Marcsekova Klaudia , Loos Christian , Rominger Frank , Doye Sven 
Published: January 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Polyfluorinated Phosphine Ligands in the Room Temperature Suzuki Cross‐Coupling Reactions.
Authors: Yekta Shahla , Cheung Lawrence , Yudin Andrei K. 
Published: January 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: A Simple Method for the Alkaline Hydrolysis of Esters.
Authors: Theodorou Vassiliki , Skobridis Konstantinos , Tzakos Andreas G. , Ragoussis Valentine 
Published: January 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis of Novel Dendritic 2,2′‐Bipyridine Ligands and Their Application to Lewis Acid Catalyzed Diels—Alder and Three‐Component Condensation Reactions.
Authors: Muraki Takahito , Fujita Ken‐ichi , Kujime Masato 
Published: January 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis of Chiral Intermediates Catalyzed by New Chiral Polymeric (Salen) Cobalt Complexes Bearing Lewis Acidic Metal Halides.
Authors: Lee Kwang Yeon , Kawthekar Rahul B. , Kim Geon‐Joong 
Published: January 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Organic Chemistry Using Weakly Electrophilic Salts: Efficient Formation of O,O‐Mixed, O,S‐ and N,O‐Acetals.
Authors: Fujioka Hiromichi , Okitsu Takashi , Ohnaka Takuya , Li Ruichuan , Kubo Ozora , Okamoto Kazuhisa , Sawama Yoshinari , Kita Yasuyuki 
Published: January 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Carbanion vs. Carbon Radical in Tandem 1,4‐Addition to Two Connected Units of Acrylate or Methacrylate.
Authors: Nagano Shinya , Hakim Siddiki S. M. A. , Sugimura Takashi 
Published: January 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: A New Strategy for the Synthesis of Benzylic Sulfonamides: Palladium‐Catalyzed Arylation and Sulfonamide Metathesis.
Authors: Grimm Jonathan B. , Katcher Matthew H. , Witter David J. , Northrup Alan B. 
Published: January 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: A Tandem Reaction of 2‐Acetylmethylene‐1,3‐dithiolanes via Fragmentation of the Dithiolane ring in the Presence of Amines: A Facile Route to Functionalized Thioamides.
Authors: Liang Fushun , Li Yan , Li Dazhi , Cheng Xin , Liu Qun 
Published: January 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Convenient Synthesis of 4‐Methylenecyclobutenones and Their Synthetic Utility as Allenylketene Precursors.
Authors: Aoyagi Shigenobu , Kikuchi Kazuma , Shimada Kazuaki , Takikawa Yuji 
Published: January 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Ruthenium‐Catalyzed Decarbonylative Cyclization of 1,6‐Diynes.
Authors: Gonzalez‐Rodriguez Carlos , Varela Jesus A. , Castedo Luis , Saa Carlos 
Published: January 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis of 1,5‐Enynes by Broensted Acid Catalyzed Substitution of Propargylic Alcohols and One‐Pot Synthesis of Bicyclo[3.1.0]hexenes.
Authors: Sanz Roberto , Martinez Alberto , Miguel Delia , Alvarez‐Gutierrez Julia M. , Rodriguez Felix 
Published: January 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.