bluuebunny/crossref_metadata_2025_split huggingface dataset:
Associations between 24-h movement behaviors and indicators of mental health and well-being across the lifespan: a systematic review
Authors: Groves Claire I. , Huong Christopher , Porter Carah D. , Summerville Bryce , Swafford Isabella , Witham Braden , Hayward Matt , Kwan Matthew Y. W. , Brown Denver M. Y. 
Published: March 2024

AbstractResearchers have adopted a variety of analytical techniques to examine the collective influence of 24-h movement behaviors (i.e., physical activity, sedentary behaviors, sleep) on mental health, but efforts to synthesize this growing body of literature have been limited to studies of children and youth. This systematic review investigated how combinations of 24-h movement behaviors relate to indicators of mental ill-being and well-being across the lifespan. A systematic search of MEDLINE, PsycINFO, Embase, and SPORTDiscus was conducted. Studies were included if they reported all three movement behaviors; an indicator of mental ill-being or well-being; and were published in English after January 2009. Samples of both clinical and non-clinical populations were included. A total of 73 studies (n = 58 cross-sectional; n = 15 longitudinal) met our inclusion criteria, of which 47 investigated children/youth and 26 investigated adults. Seven analytical approaches were used: guideline adherence (total and specific combinations), movement compositions, isotemporal substitution, profile/cluster analyses, the Goldilocks method and rest-activity rhythmicity. More associations were reported for indicators of mental ill-being (n = 127 for children/youth; n = 53 for adults) than well-being (n = 54 for children/youth; n = 26 for adults). Across the lifespan, favorable benefits were most consistently observed for indicators of mental well-being and ill-being when all three components of the 24-h movement guidelines were met. Movement compositions were more often associated with indicators of mental health for children and youth than adults. Beneficial associations were consistently observed for indicators of mental health when sedentary behavior was replaced with sleep or physical activity. Other analytic approaches indicated that engaging in healthier and more consistent patterns of movement behaviors (emphasizing adequate sleep, maximizing physical activity, minimizing sedentary behaviors) were associated with better mental health. Favorable associations were reported less often in longitudinal studies. Collectively, these findings provide further support for adopting an integrative whole day approach to promote mental well-being and prevent and manage mental ill-being over the status quo of focusing on these behaviors in isolation. This literature, however, is still emerging—for adults in particular—and more longitudinal work is required to make stronger inferences.
The effect of nonlinear diffusive coupling on the synchronization of coupled oscillators
Authors: Massihi Negar , Parastesh Fatemeh , Towhidkhah Farzad , Wang Huihai , He Shaobo , Jafari Sajad 
Published: March 2024

Abstract
This paper examines the impact of nonlinear coupling on the synchronization of interconnected oscillators. Various powers of diffusive coupling are explored to introduce nonlinear effects, and the results are contrasted with those of linear diffusive coupling. The study employs three representative chaotic systems, namely, the Lorenz, Rössler, and Hindmarsh-Rose systems. Findings indicate that nonlinear couplings with power below one result in synchronization at lower coupling strengths. Additionally, the critical coupling strength reduces as the coupling power decreases. However, the synchronization region undergoes changes and becomes bounded. Conversely, for powers exceeding one, networks are either unable to synchronize or require higher coupling strengths compared to linear coupling.
Small Incidental Pheochromocytoma Presenting With Normal or Borderline High 24-hour Urine Fractionated Metanephrines
Authors: Kwek Kevin Jun Hong , Yeo Chin Pin , Ho Bernard Chi Sern , Kon Yin Chian 
Published: March 2024

Abstract
A 73-year-old man was found to have a 2-cm lipid-poor right adrenal incidentaloma on computed tomography imaging for hematuria. Twenty-four-hour urine metanephrine was 1.1-fold elevated, then normal on repeat measurement. Paired with the second urine collection, plasma metanephrine measured by liquid chromatography tandem mass spectrometry after a 30-minute supine rest was 3.3-fold elevated. Plasma normetanephrine was 1.2-fold elevated. The 24-hour urine catecholamines and normetanephrine, measured twice, were normal. He received low-dose phenoxybenzamine and underwent successful resection of right pheochromocytoma. Postoperatively, both plasma metanephrine and normetanephrine levels normalized, using an age-appropriate upper reference limit for plasma normetanephrine. Patients who harbor small lipid-poor adrenal incidentalomas have a relatively high risk (&gt;5%) of having pheochromocytoma, indistinguishable from adenomas or carcinomas on computed tomography scan. In such cases when 24-hour urine fractionated metanephrines are normal, plasma free metanephrines measured by liquid chromatography tandem mass spectrometry under optimal sampling conditions that are 2-fold or more elevated confirm the diagnosis of pheochromocytoma. Preoperative alpha blockade followed by surgical resection is then appropriate, rather than continued monitoring with repeat urine measurements.
Gender Differences in the Pediatric Neurosurgical Workforce: Professional Practice, Work-Life Balance, and Beyond
Authors: Granek Leeat , Muzyka Logan , Limoges Natalie , Kelley‐Quon Lorraine , Lane Jessica , Ha Joseph , Benzil Deborah L. , Durham Susan 
Published: March 2024

BACKGROUND AND OBJECTIVES:
Evidence suggests that female neurosurgeons experience unique challenges in the workplace including lack of academic advancement, challenges with work-life balance, harassment, and discrimination. How these factors influence the gender gap in neurosurgery remains unclear. This analysis investigated gender differences in pediatric neurosurgeons in professional and nonprofessional activities and responsibilities.

METHODS:
A survey examining professional activities, work-life balance, family dynamics, career satisfaction, and workplace discrimination and harassment was administered to 495 pediatric neurosurgeons. Response rate was 49% (n = 241).

RESULTS:
One-third of the pediatric neurosurgical workforce is female. There were no gender differences in race/ethnicity, American Board of Neurological Surgery/American Board of Pediatric Neurological Surgery certification rates, or pediatric neurosurgery fellowship completion. No gender differences were found in operative caseload, weekly hours worked, or working after 8 pm or weekends. Women took call more frequently than men (P = .044). Men were more likely to work in academia (P = .004) and have salary subsidization from external sources (P = .026). Women were more likely to anticipate retirement by age 65 years (P = .044), were less happy with call commitments (P = .012), and worked more hours at home while off (P = .050). Women more frequently reported witnessing and experiencing racial discrimination (P = .008; P < .001), sexual harassment (P = .002, P < .001), and feeling less safe at work (P < .001). Men were more likely married (P = .042) with 1 (P = .004) or more children (P = .034). Women reported significantly greater responsibility for child and domestic care (P < .001). There were no gender differences in work-life balance, feeling supported at work, or having enough time to do things outside of work.

CONCLUSION:
Despite little difference in workload and professional responsibilities, women held more domestic responsibilities and experienced and witnessed more racial and sexual discrimination in the workplace. Surprisingly, there were no reported differences in work-life balance or feeling supported at work between genders. These findings suggest that factors unique to female neurosurgeons may contribute to continued gender disparity in the field.
Real-Time Ultrasound-Guided Posterolateral Thoracic Discectomy: 2-Dimensional Operative Video
Authors: Macki Mohamed , Chryssikos Timothy , Saab Mahdi , Tan Lee 
Published: March 2024

Symptomatic thoracic disk herniations can be challenging to treat. Various surgical approaches have been reported in the literature, but the ideal approach is still a topic of controversy. We present a step-by-step surgical video highlighting the utilization of continuous, real-time intraoperative ultrasound (IOUS) guidance for thoracic discectomy through a posterolateral approach. The background and rationale for the procedure and a detailed presentation of the sequence of surgical steps are detailed in the operative video. We believe that real-time IOUS can be used not only to gain an understanding of the ventral anatomy and to verify decompression after discectomy but it can also be used in a real-time fashion to guide the maneuvers for discectomy itself. Advantages of using real-time IOUS include real-time monitoring of the spinal cord during mobilization of the disk-osteophyte complex and direct visualization of the dura-disk herniation interface, which may enhance the safety of surgery.
The patient consented to the procedure and the publication of her image.
4.4  kW Nd:YAG slab amplifier with a high repetition frequency and high beam quality
Authors: Zhang Cheng-Gong , Dong Xue-Yan , Yan Xing-Wei , Liu Zi-Lei , Chen Quan-Hao , Li Xin-Lei , Yang Feng-Tu , Wang Hao-Zhu 
Published: March 2024

Using the self-developed fused indium wetting technology and planar waveguide, the uniform heat dissipation of the slab crystal and uniform pumping of the pump light were achieved, respectively. Based on the master oscillator power amplification (MOPA) scheme, the power was then amplified when the seed light source passed through the Nd:YAG slab crystal three times. Additionally, the image transfer system that we added to the amplified optical path achieved high beam quality. Finally, we obtained a rectangular pulsed laser with an output average power of 4461 W, a repetition frequency of 20 kHz, a pulse width of 62 ns, an optical-to-optical conversion efficiency of 26.8%, and a beam quality of β
x
=7.0 and β
y
=7.7.
On the detection, modeling, and mitigation of anomalous QoT fluctuations in optical networks
Authors: Delezoide Camille , Akbari Hassan , Ramantanis Petros , Boitier Fabien , Layec Patricia 
Published: March 2024

Monitoring data from deployed backbone networks shows that many lightpaths present large fluctuations of their quality of transmission (QoT), beyond 1 dB in range. In this paper, we investigate the hypothesis that the evidenced fluctuations stem from anomalies in polarization-dependent loss (PDL), equivalent to one large PDL element. We eventually propose and experimentally test a closed-loop automation designed to stabilize the QoT at a maximal level for lightpaths impaired by such a PDL anomaly.
Analysis of diagnostic test outcomes in a large loiasis cohort from an endemic region: Serological tests are often false negative in hyper-microfilaremic infections
Authors: Veletzky Luzia , Eberhardt Kirsten Alexandra , Hergeth Jennifer , Stelzl Daniel Robert , Zoleko Manego Rella , Kreuzmair Ruth , Burger Gerrit , Mischlinger Johannes , McCall Matthew B. B. , Mombo-Ngoma Ghyslain , Adegnika Ayôla Akim , Agnandji Selidji Todagbe , Matsiegui Pierre Blaise , Lell Bertrand , Kremsner Peter , Mordmüller Benjamin , Tappe Dennis , Ramharter Michael 
Published: March 2024

Background
The parasitic disease loiasis is associated with significant morbidity and mortality. Individuals with hyper-microfilaremia (greater than 20,000 microfilariae per mL of blood) may suffer from serious treatment-related or spontaneous adverse events. Diagnosing loiasis remains complex and primarily relies on direct parasite detection. In this study, we analyzed the performance of various diagnostic tests and the influence of parasitological and clinical factors on test outcomes in samples from individuals living in an endemic region.

Methods
Data and samples were collected from rural Gabon. Loiasis was defined as either detectable microfilaremia, or a positive history of eyeworm as assessed by the RAPLOA questionnaire. Diagnostic testing included a quantitative PCR (qPCR) for detection of Loa loa DNA in blood samples, an in-house crude L. loa antigen IgG ELISA, and a rapid test for antibodies against the Ll-SXP-1 antigen (RDT). Sensitivity and specificity were determined for each test and factors potentially influencing outcomes were evaluated in an exploratory analysis.

Results
ELISA, RDT and qPCR results were available for 99.8%, 78.5%, and 100% of the 1,232 participants, respectively. The ELISA and RDT had only modest diagnostic accuracy. qPCR was specific for L. loa microfilaremia and Cycle threshold values correlated with microfilarial density. Anti-L. loa IgG levels were highest in occult loiasis, and antibody levels correlated inversely with L. loa microfilarial density as did RDT line intensities. Only 84.6% and 16.7% of hyper-microfilaremic individuals tested positive by ELISA (11/13) and RDT (2/12), respectively.

Conclusion
None of the tests demonstrated high sensitivity and specificity for loiasis. Indirect diagnostic assays were characterized by low specificity. Additionally, hyper-microfilaremic individuals often tested negative by RDT and ELISA, indicating that these tests are not suitable for individual case management in endemic populations.
ADHD and family life: A cross-sectional study of ADHD prevalence among pupils in China and factors associated with parental depression
Authors: Lu Tao , Li Longlong , Tang Ying , Leavey Gerard 
Published: March 2024

Background
Attention Deficit Hyperactivity Disorder (ADHD) is increasingly recognized as a major problem for children and their families in China. However, its influence on parental mental health has been seldom explored.

Objective
To examine the prevalence of attention deficit hyperactivity disorder in a community sample of children aged 6–13 years, and the extent to which it impacts parental mental health.

Method
Cross-sectional study of primary school pupils (number = 2497) in Deyang, Sichuan Province, South-West China. We used standardized instruments to identify children with ADHD symptoms and parent depression.

Results
The prevalence of ADHD was 9.8%. Factors associated with the likelihood of ADHD, included family environment(P = 0.003), time spent with children(P = 0.01), parenting style(P = 0.01), and parental relationship, pupils self-harm and lower academic ability (P = 0.001). After controlling for other factors, having a child with ADHD increased the likelihood of parents’ depression (OR = 4.35, CI = 2.68~7.07), additional factors included parent relationship.

Conclusions
ADHD may be a common disorder among Chinese children, the symptoms of which may increase the likelihood of parent depression. There is a need for greater detection of ADHD in schools, acknowledgement of the challenges the disorder creates for academic success and family wellbeing, and psychoeducational tools for supporting parents of children with ADHD.
Impact of COVID-19-related experiences on health-related quality of life in cancer survivors in the United States
Authors: Otto Amy K. , Prinsloo Sarah , Natori Akina , Wagner Richard W. , Gomez Telma I. , Ochoa Jewel M. , Tworoger Shelley S. , Ulrich Cornelia M. , Ahmed Sairah , McQuade Jennifer L , Peoples Anita R. , Antoni Michael H. , Bower Julienne E. , Cohen Lorenzo , Penedo Frank J. 
Published: March 2024

Objective
Little evidence exists on the impact of the COVID-19 pandemic on cancer survivors, limiting recommendations to improve health-related quality of life (HRQoL) in this population. We describe survivors’ pandemic experiences and examine associations between COVID-19-related exposures, psychosocial experiences, and HRQoL.

Methods
Between May 2020-April 2021, survivors completed cross-sectional questionnaires capturing COVID-19-related exposures (e.g., exposure to virus, job loss); psychosocial experiences (i.e., COVID-19-related anxiety/depression, disruptions to health care and daily activities/social interactions, satisfaction with providers’ response to COVID, financial hardship, perceived benefits of the pandemic, social support, and perceived stress management ability); and HRQoL.

Results
Data were collected from N = 11,325 survivors in the United States. Participants were mostly female (58%), White (89%) and non-Hispanic (88%), and age 63 on average. Breast cancer was the most common diagnosis (23%). Eight percent of participants reported being exposed to COVID-19; 1% tested positive. About 6% of participants lost their jobs, while 24% lost household income. Nearly 30% avoided attending in-person oncology appointments because of the pandemic. Poorer HRQoL was associated with demographic (younger age; female; non-Hispanic White), clinical (Medicare; stage IV disease; hematologic/digestive/respiratory system cancer), and psychosocial factors (low perceived benefits and stress management ability; more disruption to health care and daily activities/social interactions; financial hardship).

Conclusions
COVID-19-related stressors were associated with various psychosocial experiences in cancer survivors, and these psychosocial experiences were associated with HRQoL above and beyond demographic and clinical factors.
Statistical segmentation model for accurate electrode positioning in Parkinson’s deep brain stimulation based on clinical low-resolution image data and electrophysiology
Authors: Varga Igor , Bakstein Eduard , Gilmore Greydon , May Jaromir , Novak Daniel 
Published: March 2024

Background
Deep Brain Stimulation (DBS), applying chronic electrical stimulation of subcortical structures, is a clinical intervention applied in major neurologic disorders. In order to achieve a good clinical effect, accurate electrode placement is necessary. The primary localisation is typically based on presurgical MRI imaging, often followed by intra-operative electrophysiology recording to increase the accuracy and to compensate for brain shift, especially in cases where the surgical target is small, and there is low contrast: e.g., in Parkinson’s disease (PD) and in its common target, the subthalamic nucleus (STN).

Methods
We propose a novel, fully automatic method for intra-operative surgical navigation. First, the surgical target is segmented in presurgical MRI images using a statistical shape-intensity model. Next, automated alignment with intra-operatively recorded microelectrode recordings is performed using a probabilistic model of STN electrophysiology. We apply the method to a dataset of 120 PD patients with clinical T2 1.5T images, of which 48 also had available microelectrode recordings (MER).

Results
The proposed segmentation method achieved STN segmentation accuracy around dice = 0.60 compared to manual segmentation. This is comparable to the state-of-the-art on low-resolution clinical MRI data. When combined with electrophysiology-based alignment, we achieved an accuracy of 0.85 for correctly including recording sites of STN-labelled MERs in the final STN volume.

Conclusion
The proposed method combines image-based segmentation of the subthalamic nucleus with microelectrode recordings to estimate their mutual location during the surgery in a fully automated process. Apart from its potential use in clinical targeting, the method can be used to map electrophysiological properties to specific parts of the basal ganglia structures and their vicinity.
The diagnostic accuracy of the Mini-Cog screening tool for the detection of cognitive impairment—A systematic review and meta-analysis
Authors: Abayomi Simisola Naomi , Sritharan Praveen , Yan Ellene , Saripella Aparna , Alhamdah Yasmin , Englesakis Marina , Tartaglia Maria Carmela , He David , Chung Frances 
Published: March 2024

Background
The Mini-Cog is a rapid screening tool that can be administered to older adults to detect cognitive impairment (CI); however, the accuracy of the Mini-Cog to detect CI for older patients in various healthcare settings is unclear.

Objectives
To evaluate the diagnostic accuracy of the Mini-Cog to screen for cognitive impairment in older patients across different healthcare settings.

Methods/Design
We searched nine electronic databases (including MEDLINE, Embase) from inception to January 2023. We included studies with patients ≥60 years old undergoing screening for cognitive impairment using the Mini-Cog across all healthcare settings. A cut-off of ≤ 2/5 was used to classify dementia, mild cognitive impairment (MCI), and cognitive impairment (defined as either MCI or dementia) across various settings. The diagnostic accuracy of the Mini-Cog was assessed against gold standard references such as the Diagnostic and Statistical Manual of Mental Disorders (DSM). A bivariate random-effects model was used to estimate accuracy and diagnostic ability. The risk of bias was assessed using QUADAS-2 criteria.

Results
The systematic search resulted in 4,265 articles and 14 studies were included for analysis. To detect dementia (six studies, n = 4772), the Mini-Cog showed 76% sensitivity and 83% specificity. To detect MCI (two studies, n = 270), it showed 84% sensitivity and 79% specificity. To detect CI (eight studies, n = 2152), it had 67% sensitivity and 83% specificity. In the primary care setting, to detect either MCI, dementia, or CI (eight studies, n = 5620), the Mini-Cog demonstrated 73% sensitivity and 84% specificity. Within the secondary care setting (seven studies, n = 1499), the Mini-Cog to detect MCI, dementia or CI demonstrated 73% sensitivity and 76% specificity. A high or unclear risk of bias persisted in the patient selection and timing domain.

Conclusions
The Mini-Cog is a quick and freely available screening tool and has high sensitivity and specificity to screen for CI in older adults across various healthcare settings. It is a practical screening tool for use in time-sensitive and resource-limited healthcare settings.
Facilitators and barriers to using a DeskCycle as a sedentary behavior intervention in the work environment
Authors: Odhiambo Lorriane A. , Marion Alexander J. , Harmatz Alison E. , Yala Joy A. , Callihan Thomas R. , Bundy Kristina , Zullo Melissa D. 
Published: March 2024

Background
Sedentary behavior is a public health threat with extensive health burden on society. High levels of sedentary behavior have been associated with cardiovascular diseases, diabetes, obesity, and cancer. Individuals working in desk-related occupations are more likely to be sedentary for most of the day. Health researchers have responded by implementing and promoting interventions and wellness programs in work environments to reduce this behavior. This study examined the feasibility and experience of using the DeskCycle to reduce sedentary behavior among female workers in an academic office environment.

Methods
This was an intervention study where participants used the DeskCycle in two consecutive eight-week phases and uploaded DeskCycle use data daily. A questionnaire was administered after week 2 and week 8 (pre-post) of DeskCycle use in each phase to assess dimensions of feasibility, including an open-ended question for user experience.

Results
The participants (N = 78) had an average age of 44.4 (±11.3) years and were primarily non-Hispanic White (88.5%). DeskCycle daily use varied from Phase I: 84% to 64.9% (weeks 1–7), and 49.4% in week 8, to Phase II: 73.5% to 52.2% (week 1–7), and 40.2% in week 8. In Phase I, 96.6% (week 2) and 87% (week 8) agreed that the DeskCycle decreased sedentary behavior, and in Phase II, 74.3% (week 2) and 76.9% (week 8) agreed. The analysis of open-ended responses found challenges with the desk set up, cycling interfering with typing, and thinking critically, as barriers to DeskCycle use, while enjoying cycling and cycling improving mood were reported as facilitators.

Conclusions
Using a DeskCycle in an academic office environment to reduce sedentary behavior is feasible in female office workers. Consideration should be given to the type of tasks performed while cycling.