bluuebunny/crossref_metadata_2025_split huggingface dataset:
Northeastern Caribbean Rainfall Variability Linked to Solar and Volcanic Forcing
Authors: Vieten Rolf , Warken Sophie F. , Zanchettin Davide , Winter Amos , Scholz Denis , Black David , Koltai Gabriella , Spötl Christoph 
Published: April 2024

AbstractWe present a 500‐year precipitation‐sensitive record based on co‐varying speleothem δ18O values and Mg/Ca ratios from Larga cave in Puerto Rico. This multi‐proxy record shows that the evolution of rainfall in the northeastern Caribbean was characterized by alternating centennial dry and wet phases corresponding to reduced versus enhanced convective activity. These phases occurred synchronous with relatively cool and warm tropical Atlantic sea‐surface temperatures (SSTs), respectively. While the observed pattern suggests a close link of northeastern Caribbean rainfall to the Atlantic Multidecadal Variability, a regional comparison reveals intermittent regional heterogeneity especially on decadal timescales, which may be related to a superimposing influence of the Pacific and Atlantic basins. Furthermore, the speleothem‐based hydroclimate reconstruction indicates a significant volcanic impact during the past two centuries, and further reveals a potential solar signal in the preceding three centuries. We posit that the forcing likely shifted from solar to volcanic during the eighteenth century in being an important source of multidecadal to centennial Caribbean rainfall variability. The link between convective rainfall and natural forcing may be explained through a modulation of SST variations in the tropical Atlantic and Pacific oceans.
Thank You to Our 2023 Peer Reviewers
Authors: Huber Matthew , Röhl Ursula (Ulla) 
Published: April 2024

AbstractWe would like to extend our gratitude to our amazing reviewers in 2023. We appreciate your attention to detail, your patience in working together with authors and editors through multiple rounds of revisions to ensure high quality, and of course the occasional flashes of humor and personality that shine through your reviews. Journals are only as good as their reviewers, and Paleoceanography and Paleoclimatology is lucky to have the best. Thanks again from both me and Ulla. We wish you all the best in 2024.
Atomic-scale magnetic doping of monolayer stanene by revealing Kondo effect from self-assembled Fe spin entities
Authors: Kumar Nitin , Lan Ye-Shun , Jang Iksu , Lin Yen-Hui , Chen Chia-Ju , Lin Tzu-Hsuan , Jeng Horng-Tay , Chang Po-Yao , Hsu Pin-Jui 
Published: April 2024

AbstractAtomic-scale spin entity in a two-dimensional topological insulator lays the foundation to manufacture magnetic topological materials with single atomic thickness. Here, we have successfully fabricated Fe monomer, dimer and trimer doped in the monolayer stanene/Cu(111) through a low-temperature growth and systematically investigated Kondo effect by combining scanning tunneling microscopy/spectroscopy (STM/STS) with density functional theory (DFT) and numerical renormalization group (NRG) method. Given high spatial and energy resolution, tunneling conductance (dI/dU) spectra have resolved zero-bias Kondo resonance and resultant magnetic-field-dependent Zeeman splitting, yielding an effective spin Seff = 3/2 with an easy-plane magnetic anisotropy on the self-assembled Fe atomic dopants. Reduced Kondo temperature along with attenuated Kondo intensity from Fe monomer to trimer have been further identified as a manifestation of Ruderman-Kittel-Kasuya-Yosida (RKKY) interaction between Sn-separated Fe atoms. Such magnetic Fe atom assembly in turn constitutes important cornerstones for tailoring topological band structures and developing magnetic phase transition in the single-atom-layer stanene.
Identification of the weak-to-strong transition in Alfvénic turbulence from space plasma
Authors: Zhao Siqi , Yan Huirong , Liu Terry Z. , Yuen Ka Ho , Wang Huizi 
Published: April 2024

AbstractPlasma turbulence is a ubiquitous dynamical process that transfers energy across many spatial and temporal scales in astrophysical and space plasma systems. Although the theory of anisotropic magnetohydrodynamic (MHD) turbulence has successfully described natural phenomena, its core prediction of an Alfvénic transition from weak to strong MHD turbulence when energy cascades from large to small scales has not been observationally confirmed. Here we report evidence for the Alfvénic weak-to-strong transition in small-amplitude, turbulent MHD fluctuations in Earth’s magnetosheath using data from four Cluster spacecraft. Our observations demonstrate the universal existence of strong turbulence accompanied by weak turbulent fluctuations on large scales. Moreover, we find that the nonlinear interactions of MHD turbulence are crucial to the energy cascade, as they broaden the cascade directions and fluctuating frequencies. The observed connection between weak and strong MHD turbulence systems may be present in many astrophysical environments, such as star formation, energetic particle transport, turbulent dynamos, and solar corona or solar wind heating.
Inferring gene regulatory networks from single-cell multiome data using atlas-scale external data
Authors: Yuan Qiuyue , Duren Zhana 
Published: April 2024

Abstract
Existing methods for gene regulatory network (GRN) inference rely on gene expression data alone or on lower resolution bulk data. Despite the recent integration of chromatin accessibility and RNA sequencing data, learning complex mechanisms from limited independent data points still presents a daunting challenge. Here we present LINGER (Lifelong neural network for gene regulation), a machine-learning method to infer GRNs from single-cell paired gene expression and chromatin accessibility data. LINGER incorporates atlas-scale external bulk data across diverse cellular contexts and prior knowledge of transcription factor motifs as a manifold regularization. LINGER achieves a fourfold to sevenfold relative increase in accuracy over existing methods and reveals a complex regulatory landscape of genome-wide association studies, enabling enhanced interpretation of disease-associated variants and genes. Following the GRN inference from reference single-cell multiome data, LINGER enables the estimation of transcription factor activity solely from bulk or single-cell gene expression data, leveraging the abundance of available gene expression data to identify driver regulators from case-control studies.
A multimodal physiological dataset for driving behaviour analysis
Authors: Tao Xiaoming , Gao Dingcheng , Zhang Wenqi , Liu Tianqi , Du Bing , Zhang Shanghang , Qin Yanjun 
Published: April 2024

AbstractPhysiological signal monitoring and driver behavior analysis have gained increasing attention in both fundamental research and applied research. This study involved the analysis of driving behavior using multimodal physiological data collected from 35 participants. The data included 59-channel EEG, single-channel ECG, 4-channel EMG, single-channel GSR, and eye movement data obtained via a six-degree-of-freedom driving simulator. We categorized driving behavior into five groups: smooth driving, acceleration, deceleration, lane changing, and turning. Through extensive experiments, we confirmed that both physiological and vehicle data met the requirements. Subsequently, we developed classification models, including linear discriminant analysis (LDA), MMPNet, and EEGNet, to demonstrate the correlation between physiological data and driving behaviors. Notably, we propose a multimodal physiological dataset for analyzing driving behavior(MPDB). The MPDB dataset’s scale, accuracy, and multimodality provide unprecedented opportunities for researchers in the autonomous driving field and beyond. With this dataset, we will contribute to the field of traffic psychology and behavior.
Dual pH/redox-responsive hyperbranched polymeric nanocarriers with TME-trigger size shrinkage and charge reversible ability for amplified chemotherapy of breast cancer
Authors: Badparvar Fahimeh , Marjani Ahmad Poursattar , Salehi Roya , Ramezani Fatemeh 
Published: April 2024

AbstractA novel pH/redox-responsive hyperbranched MeO-PEG-b-(NIPAAm-co-PBAE) nanoparticles (NPs) were designed with size shrinkage and charge-reversible potential for targeted delivery of docetaxel (DTX) to MDA-MB-231 cell lines. In the tumor microenvironment (TME), amine protonation induces charge reversal and disulfide bond cleavage under high TME GSH concentration causing size shrinkage, improved deep tumor penetration, and active targeting of the therapeutic agents. These nano drug delivery systems (NDDSs) significantly promoted cancer cell uptake (~ 100% at 0.5 h), facilitating site-specific delivery and deep tumor penetration. The MTT assay revealed significantly higher cytotoxicity (P value < 0.0001) for DTX-loaded NPs compared to free DTX. Cell cycle analysis revealed G2/M (58.3 ± 2.1%) and S (21.5 ± 1.3%) arrest for DTX-loaded NPs, while free DTX caused G2/M (67.9 ± 1.1%) and sub-G1 (10.3 ± 0.8%) arrest. DTX-loaded NPs induced higher apoptosis (P value < 0.001) in MDA-MB-231 cells (71.5 ± 2.8%) compared to free DTX (42.3 ± 3.1%). Western blotting and RT-PCR assays confirmed significant up-regulation of protein levels and apoptotic genes by DTX-loaded NPs compared to free DTX. In conclusion, TME-responsive charge reversal and size-shrinkable smart NDDSs designed based on low pH, and high glutathione (GSH), offer more effective site-specific delivery of therapeutic agents to tumors.
Rarefied gas flow in functionalized microchannels
Authors: Kunze Simon , Perrier Pierre , Groll Rodion , Besser Benjamin , Varoutis Stylianos , Lüttge Andreas , Graur Irina , Thöming Jorg 
Published: April 2024

AbstractThe interaction of rarefied gases with functionalized surfaces is of great importance in technical applications such as gas separation membranes and catalysis. To investigate the influence of functionalization and rarefaction on gas flow rate in a defined geometry, pressure-driven gas flow experiments with helium and carbon dioxide through plain and alkyl-functionalized microchannels are performed. The experiments cover Knudsen numbers from 0.01 to 200 and therefore the slip flow regime up to free molecular flow. To minimize the experimental uncertainty which is prevalent in micro flow experiments, a methodology is developed to make optimal use of the measurement data. The results are compared to an analysis-based hydraulic closure model (ACM) predicting rarefied gas flow in straight channels and to numerical solutions of the linearized S-model and BGK kinetic equations. The experimental data shows that if there is a difference between plain and functionalized channels, it is likely obscured by experimental uncertainty. This stands in contrast to previous measurements in smaller geometries and demonstrates that the surface-to-volume ratio of 0.4 $$\upmu$$
μ
m$$^{-1}$$

-
1

seems to be too small for the functionalization to have a strong influence and highlights the importance of geometric scale for surface effects. These results also shed light on the molecular reflection characteristics described by the TMAC.
Determinants of multimodal fake review generation in China’s E-commerce platforms
Authors: Liu Chunnian , He Xutao , Yi Lan 
Published: April 2024

AbstractThis paper develops a theoretical model of determinants influencing multimodal fake review generation using the theories of signaling, actor-network, motivation, and human–environment interaction hypothesis. Applying survey data from users of China’s three leading E-commerce platforms (Taobao, Jingdong, and Pinduoduo), we adopt structural equation modeling, machine learning technique, and Bayesian complex networks analysis to perform factor identification, path analysis, feature factor importance ranking, regime division, and network centrality analysis of full sample, male sample, and female sample to reach the following conclusions: (1) platforms’ multimodal recognition and governance capabilities exert significant negative moderating effects on merchants’ information behavior, while it shows no apparent moderating effect on users’ information behavior; users’ emotional venting, perceived value, reward mechanisms, and subjective norms positively influence multimodal fake review generation through perceptual behavior control; (2) feature factors of multimodal fake review generation can be divided into four regimes, i.e., regime 1 includes reward mechanisms and perceived social costs, indicating they are key feature factors of multimodal fake review generation; merchant perception impact is positioned in regime 2, signifying its pivotal role in multimodal fake review generation; regime 3 includes multimodal recognition and governance capabilities, supporting/disparaging merchants, and emotional venting; whereas user perception impact is positioned in regime 4, indicating its weaker influence on multimodal fake review generation; (3) both in full sample, male sample, and female sample, reward mechanisms play a crucial role in multimodal fake review generation; perceived value, hiring review control agency, multimodal recognition and governance capabilities exhibit a high degree of correlation; however, results of network centrality analysis also exhibit heterogeneity between male and female samples, i.e., male sample has different trends in closeness centrality values and betweenness centrality values than female sample. This indicates that determinants influencing multimodal fake review generation are complex and interconnected.
New insights into pterosaur cranial anatomy: X-ray imaging reveals palatal structure and evolutionary trends
Authors: Chen He , Jiang Shunxing , Kellner Alexander W. A. , Wang Xiaolin 
Published: April 2024

AbstractAmong the least studied portion of the pterosaur skeleton is the palate, which tends to be poorly preserved and commonly only visible from one side (the ventral portion). Even in well-preserved specimens, the bones tend to be fused, with the limits of individual palatal elements obscured. To shed new light on this region, we employed advanced X-ray imaging techniques on the non-pterodactyloid Kunpengopterus (Wukongopteridae), and the pterodactyloids Dsungaripterus (Dsungaripteridae), Hongshanopterus (Istiodactylidae), and Hamipterus (Hamipteridae). Our analyses revealed the presence of sutures between palatal bones in Dsungaripterus and Kunpengopterus, which resulted in different interpretations of the relation between palatine, ectopterygoid, and pterygoid, leading to a new identification of the palatal openings. Furthermore, our study shows six main observations such as the variation of the angle between the palatine rami and the variation in the relative sizes of the palatal openings. We also point out that the presence of a maxillopalatine fenestra (previously identified as postpalatine fenestra), is unique within Diapsida. Although much more work needs to be done, we showed that advanced X-ray imaging techniques open a window for understanding pterosaur cranial anatomy and provide a new perspective for investigating the evolutionary history of these flying reptiles.
Philippine Sea plate and surrounding magmatism reveal the Antarctic-Zealandia, Pacific, and Indian mantle domain boundaries
Authors: Qian Shengping , Wu Jeremy Tsung-Jui , Wu Jonny 
Published: April 2024

AbstractDelineation of geochemically distinct domains in Earth’s mantle is essential for understanding large-scale mantle convective flow and dynamics. Previous studies identify possible long-lived (>60 million-year) mantle isotopic domains (i.e. Antarctic-Zealandia, Pacific and Indian) near the Philippine Sea and western Pacific. Here we compile published basalt geochemistry of the Philippine Sea and surroundings and add new Mo isotopic and water content data for Gagua Ridge lavas, northwestern Philippine Sea, to distinguish slab-derived components during subduction. The water content, trace element, and Mo-Sr-Nd isotope compositions of Gagua Ridge arc lavas suggest that slab fluids and sediment melts are responsible for element recycling to the arc. The Philippine Sea basalts show both Indian and Zealandia-Antarctic Pb isotopic signatures; restoration of the basalt locations within a plate reconstruction shows the far-travelled Philippine Sea traversed these mantle domains. We establish the Indian mantle domain eastern boundary at ~120°E under SE Asia and the Indian Ocean. The Antarctic-Zealandia mantle domain lies south of ~10°N within the SW Pacific and has mostly remained in oceanic realms since ~400 Ma with only limited continental material input.
A polarization double-enhancement strategy to achieve super low energy consumption with ultra-high energy storage capacity in BCZT-based relaxor ferroelectrics
Authors: Sun Zixiong , Bai Yuhan , Jing Hongmei , Hu Tianyi , Du Kang , Guo Qing , Gao Pan , Tian Ye , Ma Chunrui , Liu Ming , Pu Yongping 
Published: April 2024

Due to the combination of interfacial polarization and depolarization, the energy density of BCZT-based lead-free ferroelectric reached 8.03 J cm−3 at only 425 kV cm−1. High energy density with extremely low energy consumption was achieved.
Me31B: a key repressor in germline regulation and beyond
Authors: Gao Ming 
Published: April 2024

Abstract
Maternally Expressed at 31B (Me31B), an evolutionarily conserved ATP-dependent RNA helicase, plays an important role in the development of the germline across diverse animal species. Its cellular functionality has been posited as a translational repressor, participating in various RNA metabolism pathways to intricately regulate the spatiotemporal expression of RNAs. Despite its evident significance, the precise role and mechanistic underpinnings of Me31B remain insufficiently understood. This article endeavors to comprehensively review historic and recent research on Me31B, distill the major findings, discern generalizable patterns in Me31B’s functions across different research contexts, and provide insights into its fundamental role and mechanism of action. The primary focus of this article centers on elucidating the role of Drosophila Me31B within the germline, while concurrently delving into pertinent research on its orthologs within other species and cellular systems.
Extrinsic Laryngeal Muscle Activity With Different Diameters and Water Depths in a Semi-Occluded Vocal Tract Exercise
Authors: Cha Junseo , Kim Chaehyun , Choi Seong Hee 
Published: April 2024

Purpose:
Surface electromyography (sEMG) has been used to evaluate extrinsic laryngeal muscle activity during swallowing and phonation. In the current study, sEMG amplitudes were measured from the infrahyoid and suprahyoid muscles during phonation through a tube submerged in water.

Method:
The sEMG amplitude values measured from the extrinsic laryngeal muscles and the electroglottographic contact quotient (CQ) were obtained simultaneously from 62 healthy participants (31 men, 31 women) during phonation through a tube at six different depths (2, 4, 7, 10, 15, and 20 cm) while using two tubes with different diameters (1 and 0.5 cm).

Results:
With increasing depth, the sEMG amplitude for the suprahyoid muscles increased in men and women. However, sEMG amplitudes for the infrahyoid muscles increased significantly only in men. Tube diameter had a significant effect on the suprahyoid sEMG amplitudes only for men, with higher sEMG amplitudes when phonating with a 1.0-cm tube. CQ values increased with submerged depth for both men and women. Tube diameter affected results such than CQ values were higher for men when using the wider tube and for women with the narrower tube.

Conclusions:
Vocal fold vibratory patterns changed with the depth of tube submersion in water for both men and women, but the patterns of muscle activation differed between the sexes. This suggests that men and women use different strategies when confronted with increased intraoral pressure during semi-occluded vocal tract exercises. In this study, sEMG provided insight into the mechanism for differences between vocally normal individuals and could help detect compensatory muscle activation during tube phonation in water for people with voice disorders.
Die Irrtümer hinter der SIDS-Bauchlagekatastrophe
Authors: Paditz Ekkehart 
Published: April 2024

ZUSAMMENFASSUNGDie SIDS-Häufigkeit konnte in Deutschland nach 1991 um mehr als 93 % vermindert werden, da in mehr als 40 Fall-Kontrollstudien nach Kriterien der Evidenzbasierten Medizin mehrere beeinflussbare SIDS-Risikofaktoren identifiziert werden konnten, zu denen insbes. auch die Bauchlage als Schlafposition von Säuglingen gehört.Alfred Fabian Hess und David Greene setzten das pandemische Ereignis der SIDS-Bauchlagekatastrophe ungewollt in Gang, da sie 1931 ohne Faktenbasis behaupteten, dass Symmetrie das Prinzip des Lebens sei, sodass auch der kindliche Schädel symmetrisch sein müsse. Ohne entsprechende Laborbefunde behaupteten sie, dass sehr oft eine fetale Hypokalziämie vorliegen würde, die sich dann in einer Weichheit der Rippen und des knöchernen Schädels manifestieren würde, ohne dass klinisch, laborchemisch und röntgenologisch eine Rachitis vorlag. Hess präsentierte 2 Kinder, bei denen gleichzeitig weiche Rippen und okzipitale Abflachungen vorlagen. Greene berichtete über 6 Säuglinge mit okzipitaler Asymmetrie, die sich in 4 Fällen durch Fixierung des Kopfes mit Kopfhauben, Pflastern und Bändern verminderte.Auf der Grundlage dieser spärlichen Datenbasis proklamierte Hess ein neues Syndrom mit weichen Rippen und Schädelasymmetrie, das erhebliche respiratorische Probleme bis zum letalen Ausgang verursachen könne. Greene polemisierte gegen die Rückenlage und rief zur Änderung der Lagerung von Säuglingen auf. Angesichts der erheblichen Autorität von Hess, der aufgrund seiner Verdienste in der Rachitisforschung mehrfach für den Nobelpreis vorgeschlagen wurde, setzten sich die Auffassungen von Hess und Greene für einige Jahrzehnte durch.
Diagnostik und Therapie der obstruktiven Schlafapnoe im Säuglingsalter am Beispiel der Robin-Sequenz
Authors: Quante Mirja , Poets Christian Friedrich , Wiechers Cornelia 
Published: April 2024

ZUSAMMENFASSUNGSäuglinge haben aufgrund ihrer besonderen Anatomie eine Prädisposition für ein obstruktives Schlafapnoe-Syndrom (OSAS). Prävalenzzahlen sind allerdings kaum bekannt. Klinisch präsentiert sich ein OSAS in dieser Altersgruppe äußerst variabel. Bei Verdachtsmomenten für das Vorliegen eines OSAS ist daher eine Schlaflaboruntersuchung unerlässlich. Therapeutisch gibt es neben der Möglichkeit einer nächtlichen atemunterstützenden Therapie bei Säuglingen mit Robin-Sequenz die Option, ein spezielles Therapieverfahren aus Spornplatte, Logopädie und Trinktraining einzusetzen.
Schlaf von (werdenden) Müttern
Authors: Poulain Tanja , Kiess Wieland 
Published: April 2024

ZUSAMMENFASSUNGWir haben untersucht, inwiefern der Schlaf von Müttern und schwangeren Frauen mit dem Alter der eigenen Kinder und der Schlafkonstellation zusammenhängt. Dafür wurden 380 Frauen (mittleres Alter 38 Jahre) mittels Pittsburgh Sleep Quality Index (PSQI) zu ihrem Schlaf und zur Häufigkeit von Bedsharing (Schlafen mit Kind im gleichen Bett) befragt. Die Frauen waren entweder gerade schwanger oder hatten Kinder im Alter von 3 Monaten, 6 Monaten, 1, 2, 8 oder 13 Jahren. In jedem der unterschiedlichen Bereiche des PSQI erzielten mehr als 10 % der Befragten auffällige Werte (Beispiel Schlafqualität: 32 %). Der Schlaf war schlechter, wenn Bedsharing vorlag (z. B. auffällige Werte Schlafqualität: 43 % bei Bedsharing vs. 25 % ohne Bedsharing). Im Vergleich zum Schlaf von Müttern 13-jähriger Kinder war der Schlaf von Müttern jüngerer Kinder signifikant schlechter (z. B. auffällige Werte Schlafqualität: 29–50 % bei Müttern jüngerer Kinder vs. 16 % bei Müttern 13-Jähriger). Die Ergebnisse legen nah, dass junge Kinder im Haushalt und vor allem Bedsharing den Schlaf von Müttern stören können und daher bei Müttern besonders auf Schlafprobleme geachtet bzw. diesen entgegengewirkt werden sollte.