bluuebunny/crossref_metadata_2025_split huggingface dataset:
Giuseppe FLAMMINI (ed.), Hermeneumata Pseudodositheana Leidensia. Bibliotheca Scriptorum Graecorum et Romanorum Teubneriana
Authors: Rochette Bruno 
Published: February 2008

Abstract
Méthode d'étude du latin – et plus tard aussi du grec – pour grands débutants, les Hermeneumata Pseudodositheana (HP) – ainsi improprement appelés parce qu'ils sont placés, dans le Codex Sangallensis 902, immédiatement après l'Ars Dosithei magistri – étaient destinés à des Grecs de l'Empire romain qui voulaient apprendre le latin. La connaissance de la langue de Rome était en effet indispensable pour accéder à des postes importants dans l'administration, l'armée ou la justice, surtout après les réformes dioclétiennes. Composés sans doute au IIIe s. – la 4e section de la recension de Leyde date du 11 septembre 207 (CGL, III, 56, 30–34), ces manuels bilingues très diffusés dans l'Europe carolingienne font penser à notre méthode moderne Assimil. Sorte de Lehrbuch à finalité pratique, ils nous sont parvenus non dans un texte unique, mais dans neuf recensions différentes, conservées par une cinquantaine de manuscrits occidentaux: Hygini Herm. (HH), Herm. Montepessulana (HMp), Herm. Bruxellensia (HB), Herm. Stephani (HS), Herm. Leidensia (HL), Herm. Monacensia (HM), Herm. Einsidlensia (HE), Herm. Vaticana (HV), réédités récemment par G. Brugnoli et M. Buonocore, dont l'auteur est sans doute chrétien, et Hermeneumata Celtis (HC). Vu l'impossibilité de reconstituer les rapports de dépendance entres ces diverses recensions, elles ont été éditées séparément dans le troisième volume du Corpus Glossariorum Latinorum de G. GOETZ (Leipzig 1892). Ce n'est que tout récemment que FLAMMINI (F.) a tenté un examen de la recensio plenior Leidensis en vue d'établir le texte critique des HP. Après avoir présenté les résultats de cette enquête dans un article intitulé Prolegomena alla recensio plenior degli ‘Hermeneumata Pseudodositheana’, dans Giornale Italiano di Filologia 42, 1990, p. 3–43, il publie maintenant le texte dans la Bibliotheca Teubneriana.
Christopher S. LIGHTFOOT (ed.), Amorium Reports II. Research papers and technical reports. BAR International Series, 1170
Authors: Böhlendorf-Arslan Beate 
Published: February 2008

Abstract
Nach der ersten Publikation der Ergebnisse der Ausgrabungen von Amorium (M. GILL u. a., Amorium Reports, Finds I: The Glass (1987-1997). BAR Int. Series, 1070), Oxford 2002) liegt nun der zweite Band vor, der neben Forschungsberichten (Teil A) auch technische Untersuchungen (Teil B) verschiedener Bearbeiter umfaßt.
Maria G. PARANI, Reconstructing the reality of images. Byzantine material culture and religious iconography (11th to 15th centuries). The Medieval Mediterranean, 41
Authors: Piltz Elisabeth 
Published: February 2008

Abstract
In the last decades an increasing interest in everyday life in Byzantium has been manifested, not the least stimulated by the Birmingham Spring Symposia. Official and private collections have been brought to light. Maria PARANI (P.) has ventured to write a study not only about official and everyday furniture and implements but in the same work about the transmission of imperial insignia to the ecclesiastical realm. This work is an impressive scholarly accomplishment, written with much enthusiasm with beautiful layout and excellent quality of the illustrations.
Anastasios K. SINAKOS, Άνθϱωπος ϰαι πεϱιβάλλον στην πϱωτοβυζαντινή εποχή (4ος–6ος αι.). Вιβλιοθήϰη Ιστοϱιϰών Мελετών, 3
Authors: Telelis Ioannis 
Published: February 2008

Abstract
Although environmental history has emerged as a distinct historical field only since the late 1960s, it has a long ancestry. The idea that human society (and hence history) is affected by physical environment can be traced back as far as ancient Greece; ideas of climatic and geographical determinism were also widespread in the eighteenth and nineteenth century Europe. Modern environmental history has, however, been shaped by the development of historical geography and agrarian history, by attempts to establish a more scientific basis for history, and, more recently, by growing concern about environmental degradation. Modern environmental history can also be understood as part of a wider reaction against an older history of nations, states and “great men and women”. Byzantine studies too, have not avoided this “environmentalism”. Since the early 1980s various studies concerning aspects of historical geography of the Byzantine period have appeared.
Prediction of Effective Porosity of Contaminated Fine Grained Soils Using Electrical Properties
Authors: Meegoda Jay N. , Ratnaweera Prasanna 
Published: February 2008

Abstract
The effective porosity is a required parameter for mass flow rate calculations in groundwater hydrogeology and movement of contaminants through clay liners. It is also an important soil parameter in geotechnical engineering. In this manuscript, a laboratory methodology based on electrical properties of soils is proposed to estimate the effective porosity of contaminated soils. Based on the cluster model proposed by Olsen 1962 and the three possible electrical current paths through soils, a three-element electrical model is proposed. Bulk electrical properties of a soil element were mathematically derived for input frequencies of 1–100 MHz. The bulk electrical properties of three soils at different confining pressures in both horizontal and vertical directions were measured for the said frequency range. The measured and the predicted bulk electrical properties of soil were compared; the predictions were used to establish effective porosity of the soil element. The predicted effective porosity values for three soils under different chemical environments were compared with those measured using tracer test. The comparisons show that electrical measurements could predict effective porosities of contaminated fine grained soils. These measurements can then be used to estimate in situ effective porosities, to be used in contaminant transport models.
IGF-I increases the recruitment of GLUT4 and GLUT3 glucose transporters on cell surface in hyperthyroidism
Authors: Dimitriadis George , Maratou Eirini , Boutati Eleni , Kollias Anastasios , Tsegka Katerina , Alevizaki Maria , Peppa Melpomeni , Raptis Sotirios A , Hadjidakis Dimitrios J 
Published: February 2008

ObjectiveIn hyperthyroidism, tissue glucose disposal is increased to adapt to high energy demand. Our aim was to examine the regulation of glucose transporter (GLUT) isoforms by IGF-I in monocytes from patients with hyperthyroidism.Design and methodsBlood (20 ml) was drawn from 21 healthy and 10 hyperthyroid subjects. The abundance of GLUT isoforms on the monocyte plasma membrane was determined in the absence and presence of IGF-I (0.07, 0.14, and 0.7 nM) using flow cytometry. Anti-CD14-phycoerythrin monocional antibody was used for monocyte gating. GLUT isoforms were determined after staining the cells with specific antisera to GLUT3 and GLUT4.ResultsIn monocytes from the euthyroid subjects, IGF-I increased the abundance of GLUT3 and GLUT4 on the monocyte surface by 25 and 21% respectively (P<0.0005 with repeated measures ANOVA). Hyperthyroidism increased the basal monocyte surface GLUT3 and GLUT4; in these cells, IGF-I had a marginal but highly significant effect (P=0.003, with repeated measures ANOVA) on GLUT3 (11%) and GLUT4 (10%) translocation on the plasma membrane.ConclusionsIn hyperthyroidism: 1) basal abundance of GLUT3 and GLUT4 on the plasma membrane is increased and 2) the sensitivity of the recruitment of GLUT3 and GLUT4 transporters on the plasma membrane in response to IGF-I is increased. These findings may contribute to the understanding of the mechanism by which hyperthyroidism increases glucose disposal in peripheral tissues.
Serum concentrations and expressions of serum amyloid A and leptin in adipose tissue are interrelated: the Genobin Study
Authors: Lappalainen T , Kolehmainen M , Schwab U , Pulkkinen L , Laaksonen D E , Rauramaa R , Uusitupa M , Gylling H 
Published: February 2008

ObjectiveSerum amyloid A (SAA) is a novel link between increased adipose tissue mass and low-grade inflammation in obesity. Little is known about the factors regulating its serum concentration and mRNA levels. We investigated the association between SAA and leptin in obese and normal weight subjects and analyzed the effect of weight reduction on serum SAA concentration and gene expression in adipose tissue of the obese subjects.MethodsSeventy-five obese subjects (60±7 years, body mass index (BMI) 32.9±2.8 kg/m2, mean±s.d.) with impaired fasting plasma glucose or impaired glucose tolerance and other features of metabolic syndrome, and 11 normal weight control subjects (48±9 years, BMI 23.7±1.9 kg/m2) were studied at the baseline. Twenty-eight obese subjects underwent a 12-week intensive weight reduction program followed by 5 months of weight maintenance. Blood samples and abdominal s.c. adipose tissue biopsies were taken at the baseline and after the follow-up. Gene expression was studied using real-time quantitative PCR.ResultsThe gene expressions in women and serum concentrations of leptin and SAA were interrelated independently of body fat mass in the obese subjects (r=0.54, P=0.001; r=0.24, P=0.039 respectively). In multiple linear regression analyses, leptin mRNA explained 38% of the variance in SAA mRNA (P=0.002) in the obese women. Weight loss of at least 5% increased SAA mRNA expression by 48 and 36% in men and women, but serum SAA concentrations did not change.ConclusionsThe association between SAA and leptin suggests an interaction between these two adipokines, which may have implications in inflammatory processes related to obesity and the metabolic syndrome.
Leptin and adiponectin concentrations in intrauterine growth restricted and appropriate for gestational age fetuses, neonates, and their mothers
Authors: Kyriakakou Marialena , Malamitsi-Puchner Ariadne , Militsi Helen , Boutsikou Theodora , Margeli Alexandra , Hassiakos Demetrios , Kanaka-Gantenbein Christina , Papassotiriou Ioannis , Mastorakos George 
Published: February 2008

ObjectiveLeptin and adiponectin are two adipocytokines that play a critical role in the control of energy balance and metabolism as well as in conditions, such as insulin resistance, inflammation, and the development of the metabolic syndrome in adult life. Leptin has been associated with asymmetric intrauterine growth restriction (IUGR). The aim of this study was to investigate the perinatal implication of leptin and adiponectin in IUGR.DesignLeptin and adiponectin were measured in the plasma of 40 mothers, in the umbilical cord (UC) blood of their 20 appropriate for gestational age (AGA) and 20 IUGR singleton, full-term fetuses, and neonates on day 1 (d1) and day 4 (d4) of life postnatally.MethodsSerum leptin and adiponectin levels were measured by RIA. Serum cortisol levels were measured with an electrochemiluminescence immunoassay.ResultsLeptin and adiponectin serum levels were higher and lower respectively in IUGR (mean±s.e.m., 32.5±3.8 and 5.4±0.9 μg/l respectively) compared with AGA (20.4±2.1 and 11.8±1.3 μg/l respectively) mothers (P<0.05), although body mass index did not differ between these two groups. Leptin levels positively correlated with adiponectin levels in the AGA (r=0.547, P<0.05) but not in the IUGR mothers. UC, d1, and d4 leptin and adiponectin levels did not differ between IUGR and AGA groups. UC were significantly higher than d1 leptin levels (P<0.05) in the IUGR group but not in the AGA group.ConclusionsThe increased UC leptin levels compared with d1 in IUGR fetuses might be directly and/or indirectly related to the subsequent development of insulin resistance in these neonates. This pathologic situation seems to be related to a specific profile of increased leptin and decreased adiponectin levels in IUGR mothers indicating a genetic predisposition for the development of insulin resistance.
Pheochromocytoma crisis induced by glucocorticoids: a report of four cases and review of the literature
Authors: Rosas Alejandro L , Kasperlik-Zaluska Anna A , Papierska Lucyna , Bass Barbara Lee , Pacak Karel , Eisenhofer Graeme 
Published: February 2008

ContextPheochromocytoma crisis (PC) is a rare life-threatening endocrine emergency that may present spontaneously or can be unmasked by ‘triggers’, including certain medications that provoke the release of catecholamines by tumors. Several isolated cases of PC have been reported after administration of exogenous glucocorticoids; evidence that these drugs cause adverse events in patients with pheochromocytoma is mainly anecdotal.PatientsWe report four cases of PC most likely induced by glucocorticoids and review seven previous reports in the literature linking steroid administration to the development of PC.ResultsIn four new cases reported here, glucocorticoid administration was associated with a fatal outcome in one case, a pheochromocytoma multisystem crisis in another, and serious hypertensive crises in two others. Two patients had incidental adrenal masses and were undergoing high-dose dexamethasone suppression tests (DST).ConclusionsExogenous glucocorticoids may unpredictably trigger PC. Pheochromocytoma should be included in the differential diagnosis of any patient who develops a hypertensive crisis, cardiac failure, tachycardia, headache, and abdominal or chest pain after receiving exogenous glucocorticoids. Glucocorticoid induced PC is frequently associated with hemorrhagic pheochromocytoma. Although exogenous glucocorticoids cause serious complications unpredictably, they should be avoided or administered only if necessary and with caution in patients with known or suspected pheochromocytoma. During the investigation of incidental adrenal masses, pheochromocytoma should ideally be ruled out before administering glucocorticoids. However, no cases have been reported with 1 mg of dexamethasone when given as a DST in patients with pheochromocytoma; larger doses, as low as 2 mg of dexamethasone, may trigger a PC. A patient with pheochromocytoma presenting as an adrenal incidentaloma may also be at risk if exposed to glucocorticoids given as pre-treatment in case of allergy to contrast media.
Tumor producing fibroblast growth factor 23 localized by two-staged venous sampling
Authors: van Boekel Gerben , Ruinemans-Koerts Janneke , Joosten Frank , Dijkhuizen Paul , van Sorge Adriaan , de Boer Hans 
Published: February 2008

BackgroundTumor-induced osteomalacia is a rare paraneoplastic syndrome characterized by hypophosphatemia, renal phosphate wasting, suppressed 1,25-dihydroxyvitamin D production, and osteomalacia. It is caused by a usually benign mesenchymal tumor producing fibroblast growth factor 23 (FGF-23). Surgical excision of the tumor is the first choice of treatment because complete resection is curative. Unfortunately, localization often fails due to the small size of these neoplasms. According to the current standards, supportive care with oral phosphate and calcitriol is the only feasible option in such cases.CaseIn this report, we describe the diagnostic value of two-staged venous sampling to localize the FGF-23 secreting tumor in a case where conventional imaging failed. In addition, we examined the effect of dipyridamole on renal phosphate excretion, explored the efficacy of octreotide and calcitonin to suppress the FGF-23 production, and closely evaluated the hormonal changes following successful removal of the tumor. The latter observations indicate that calcitonin may be useful to suppress tumor-FGF-23 production and that FGF-23 may be a clinically relevant inhibitor of parathyroid hormone secretion in man.
Osteoprotegerin in relation to body weight, lipid parameters insulin sensitivity, adipocytokines, and C-reactive protein in obese and non-obese young individuals: results from both cross-sectional and interventional study
Authors: Gannagé-Yared Marie-Hélène , Yaghi Cesar , Habre Bassem , Khalife Simon , Noun Roger , Germanos-Haddad Myrna , Trak-Smayra Viviane 
Published: February 2008

ObjectiveWe analyzed the relation of osteoprotegerin (OPG) with insulin sensitivity, lipid profile, serum glutamic pyruvic transaminase (SGPT), adipocytokines, and C-reactive protein (CRP) in obese and non-obese subjects.MethodsIn the study, 170 subjects (106 obese and 64 non-obese, sex ratio female/male=2.03) were included. Thirty-two obese subjects were reevaluated 6 months after the weight loss induced by bariatric surgery.ResultsOPG did not differ between obese and non-obese subjects (respective mean values 5.17 and 4.96 pmol/l) or according to gender, but was positively correlated with age (P<0.0001 for both groups). OPG was statistically higher in 18 obese diabetic subjects compared with non-diabetics (P=0.03). After adjustment for age, no significant correlation was found between OPG and body mass index (BMI), waist, systolic and diastolic blood pressure, cholesterol, triglycerides, high density lipoprotein (HDL) cholesterol, leptin, and adiponectin in both the obese and non-obese subjects. However, OPG was positively correlated with homeostasis model assessment (HOMA) index and SGPT levels in obese subjects at baseline (r=0.295, r=0.20, P<0.05) and after adjustment for age (r=0.28, r=0.20, P<0.05). OPG was also significantly correlated with CRP; this correlation persisted after adjustment for age in obese subjects (r=0.30, P<0.01). In a multivariate analysis in the obese group, HOMA index and CRP were independent predictors of OPG while SGPT was not. Six months post-surgery, OPG did not change, despite a significant reduction in glucose, SGPT, cholesterol, triglycerides, CRP, and leptin values (P=0.02, P=0.006, P=0.007, P<0.001, P<0.001, P<0.001 respectively) and a significant increase in adiponectin and HDL values (P<0.001 for both variables).ConclusionOur results show that in obese subjects, OPG is not related to BMI. However, we describe new relationships between OPG and both HOMA index and CRP.
Women gain weight and fat mass despite lipectomy at abdominoplasty and breast reduction
Authors: Rinomhota A S , Bulugahapitiya D U S , French S J , Caddy C M , Griffiths R W , Ross R J M 
Published: February 2008

ObjectivesIn animal models, fat removal results in compensatory weight gain. No study has reported measurement of weight following lipectomy in humans. We have examined changes in weight in patients who underwent lipectomy.MethodsIn a retrospective analysis, 16 patients who had abdominoplasty and 17 patients who underwent bilateral breast reduction were compared with 16 patients who had carpal tunnel syndrome release. Following this, a prospective study was carried out on 7 subjects awaiting abdominoplasty and 12 subjects awaiting bilateral breast reduction surgery.ResultsIn the retrospective study, all three patient groups gained weight following surgery. The abdominoplasty group was heavier before surgery and showed greatest weight gain but there was no statistically significant difference in weight gain between the groups. In the prospective study, the abdominoplasty group had a mean fat removal of 1.77 kg and breast reduction group had a mean of 3.22 kg. Eighteen months following surgery the abdominoplasty group showed a significant mean increase in body weight (mean increase: 4.82 kg) and body mass index (BMI) (mean increase: 1.66 kg/m2). In the bilateral breast reduction group, there was a non-significant mean gain in weight (mean increase: 0.67 kg) and BMI (mean increase: 0.21 kg/m2).ConclusionsPatients undergoing lipectomy during abdominoplasty and bilateral breast reduction will gain weight in the long term. This weight gain probably reflects the expected gain in weight without surgery as a similar finding is observed in patients who have undergone surgery without lipectomy. These results highlight the limitation of lipectomy as a weight control measure.
Short‐term Safety and Tolerability of a Once‐Daily Fixed‐Dose Abacavir‐Lamivudine Combination versus Twice‐Daily Dosing of Abacavir and Lamivudine as Separate Components: Findings from the ALOHA Study
Authors: Cohen Calvin J. , Kubota Marshall , Brachman Philip S. , Harley William B. , Schneider Stefan , Williams Vanessa C. , Sutherland‐Phillips Denise H. , Lim Michael L. , Balu Rukmini B. , Shaefer Mark S. 
Published: February 2008

Study Objective. To evaluate the short‐term (12 wks) safety and tolerability of a once‐daily, fixed‐dose abacavir‐lamivudine combination versus twice‐daily dosing of the separate components, both with background antiretroviral therapy.Design. Phase IIIB, randomized, open‐label, parallel‐group, multicenter study.Setting. One hundred forty‐six human immunodeficiency virus (HIV) clinics.Patients. Six hundred eighty antiretroviral therapy‐naive patients with HIV type 1 RNA greater than 1000 copies/ml at baseline.Intervention. Patients were randomly assigned in a 2:1 manner to receive either abacavir 600 mg‐lamivudine 300 mg once/day or abacavir 300 mg twice/day and lamivudine 150 mg twice/day. Subjects were stratified based on choice of third or fourth antiretroviral drug (nucleoside reverse transcriptase inhibitor [NRTI], NNRTI, or protease inhibitor), assigned before randomization.Measurements and Main Results. The primary end point was occurrence of grades 2–4 adverse events and serious adverse events; abacavir hypersensitivity reactions were considered serious adverse events. Baseline characteristics were similar between the once‐daily (455 patients) and twice‐daily (225 patients) groups. The rates of all grades 2–4 adverse events were similar: once‐daily 33% (150 patients), twice‐daily 31% (69). A slightly larger proportion of patients in the twice‐daily group experienced drug‐related grades 2–4 adverse events: once‐daily 10% (47), twice‐daily 16% (36). Rates of all serious adverse events (once‐daily 11% [49], twice‐daily 10% [22]) and drug‐related serious adverse events (once‐daily 5% [21], twice‐daily 8% [17]) were similar. The rate of suspected abacavir hypersensitivity reaction was 5.3% (once‐daily 4.4% [20], twice‐daily 7.1% [16]), with a higher rate for the NNRTI stratum of the twice‐daily group (8.6% [10]) than in any other stratum (once‐daily, NNRTI 4.3% [10]; twice‐daily, protease inhibitor 5.6% [6]; once‐daily, protease inhibitor 4.6% [10]).Conclusion. In the short‐term, the rates of adverse events in the once‐daily and twice‐daily groups appeared to be similar. The rate of suspected abacavir hypersensitivity reaction in the once‐daily group was lower than the rate in the twice‐daily group.