bluuebunny/crossref_metadata_2025_split huggingface dataset:
A Delphi consensus on clinical features, diagnosis and treatment of major depressive disorder patients with anhedonia amongst psychiatrists in the Asia-Pacific
Authors: Cheng Calvin , Herr Keira , Jeon Hong Jin , Kato Tadafumi , Ng Chee H. , Yang Yen Kuang , Zhang Ling 
Published: February 2024

BackgroundAnhedonia, a core diagnostic feature for major depressive disorder (MDD), is defined as the loss of pleasure and interest in daily activities. Its prevalence in MDD patients vary from 35 to 70%. Anhedonia in MDD negatively impacts functioning and is associated with treatment resistance and poorer prognosis for various clinical outcomes. Owing to its complexity, there remains considerable heterogeneity in the conceptualization, diagnosis and clinical management of anhedonia in MDD.MethodsThis modified Delphi panel was conducted to elicit expert opinion and establish consensus on concepts relating to clinical features, diagnosis and treatment of MDD with anhedonia (MDDwA) amongst psychiatrists in the Asia-Pacific region. Seven themes were covered. A three-stage process was adopted for consensus generation (two online survey rounds, followed by a moderated consensus meeting). Statements were developed based on a literature review and input from a steering committee of six regional experts. The panel included 12 psychiatrists practicing in Australia, China, Hong Kong, Japan, South Korea and Taiwan with ≥5 years of specialist clinical experience, including assessment or management of patients with MDDwA.ResultsOverall, consensus was achieved (median ≥8) on 89/103 statements (86%). About half of the statements (55/103, 53%) achieved consensus in Round 1, and 29/36 modified statements achieved consensus in Round 2. At the moderated consensus meeting, five modified statements were discussed by the steering committee and consensus was achieved on all statements (5/5). The findings highlighted a lack of clear and practical methods in clinical practice for assessing anhedonia in MDD patients and limited physician awareness of anhedonia in Asia-Pacific.ConclusionInsights from this Delphi consensus provide a reference point for psychiatrists in Asia-Pacific to optimize their strategies for personalized diagnosis and management of patients with MDDwA. Identification of distinct and clinically relevant subtypes in MDD may be valuable for guiding personalized diagnosis and management approaches, including type-specific therapies.
Prevalence and associated factors of depression, anxiety and stress among clinical therapists in China in the context of early COVID-19 pandemic
Authors: Tao Rui , Li Wenzheng , Min Kaiyuan , Mo Daming , Geng Feng , Xia Lei , Liu Tingfang , Liu Yuanli , Jiang Feng , Liu Huanzhong , Tang Yi-lang 
Published: February 2024

ObjectivesTo study the socio-demographic characteristics and the prevalence of depression, anxiety, and stress among clinical therapists in China during the early Coronavirus disease 2019 (COVID-19) pandemic and to identify associated factors.MethodThis cross-sectional study was part of a multicenter, nationally representative survey conducted through WeChat from January 2021 to March 2021. Data, including socio-demographics, health-related behaviors, and information on whether they participated in the frontline work of treating COVID-19, were collected anonymously. Respondents also completed the Depression Anxiety Stress Scales-21 (DASS-21).ResultsIn total, 396 clinical therapists in the selected hospitals completed the questionnaires, with a response rate of 89.0%. Respondents were predominantly female (77.3%). About 6.6% of the participants were current tobacco users, and 20.7% had participated in the frontline work of treating COVID-19. Overall, 22.0%, 17.9%, and 8.8% of participants were classified as having clinically meaningful depression, anxiety, and stress, respectively, based on DASS-21 scores. Multiple logistic regression in Model 1 and Model 2 showed that depression, anxiety, and stress were associated with regular physical activity and frequent insomnia (all, p &lt; 0.05). In anxiety model 2, the associated factors for anxiety during the pandemic were identified as education (master’s degree or more, OR=0.520; 95% CI=0.283-0.955), marital status (single, OR=2.064; 95% CI=1.022-4.168), tobacco use (OR=4.265; 95% CI=1.352-13.454), regular physical activity (OR=0.357; 95% CI=0.192-0.663), frequent insomnia (OR=6.298; 95% CI =2.522-15.729), and participation in the frontline work of treating COVID-19 (OR=3.179; 95% CI=1.697-5.954). The COVID-19 epidemic did not significantly increase the depression and stress levels among clinical therapists, but it did significantly increase anxiety levels.ConclusionDuring the COVID-19 pandemic, depression, anxiety and stress were relatively common among clinical therapists in China. Regular physical activity and good sleep were important protective factors against emotional problems. Therefore, encouraging regular physical activity and actively addressing clinical therapists’ sleep problems is beneficial to improving the ability to cope with negative emotions. The COVID-19 epidemic significantly increased anxiety, and awareness and interventions should be recommended to reduce anxiety among clinical therapists during the COVID-19 pandemic.
Immunogenicity of RV1 and RV5 vaccines administered in standard and interchangeable mixed schedules: a randomized, double-blind, non-inferiority clinical trial in Mexican infants
Authors: Macías-Parra Mercedes , Vidal-Vázquez Patricia , Reyna-Figueroa Jesús , Rodríguez-Weber Miguel Ángel , Moreno-Macías Hortensia , Hernández-Benavides Inés , Fortes-Gutiérrez Sofía , Richardson Vesta Louise , Vázquez-Cárdenas Paola 
Published: February 2024

IntroductionRotavirus-associated diarrheal diseases significantly burden healthcare systems, particularly affecting infants under five years. Both Rotarix™ (RV1) and RotaTeq™ (RV5) vaccines have been effective but have distinct application schedules and limited interchangeability data. This study aims to provide evidence on the immunogenicity, reactogenicity, and safety of mixed RV1-RV5 schedules compared to their standard counterparts.MethodsThis randomized, double-blind study evaluated the non-inferiority in terms of immunogenicity of mixed rotavirus vaccine schedules compared to standard RV1 and RV5 schedules in a cohort of 1,498 healthy infants aged 6 to 10 weeks. Participants were randomly assigned to one of seven groups receiving various combinations of RV1, and RV5. Standard RV1 and RV5 schedules served as controls of immunogenicity, reactogenicity, and safety analysis. IgA antibody levels were measured from blood samples collected before the first dose and one month after the third dose. Non-inferiority was concluded if the reduction in seroresponse rate in the mixed schemes, compared to the standard highest responding scheme, did not exceed the non-inferiority margin of −0.10. Reactogenicity traits and adverse events were monitored for 30 days after each vaccination and analyzed on the entire cohort.ResultsOut of the initial cohort, 1,365 infants completed the study. Immunogenicity analysis included 1,014 infants, considering IgA antibody titers ≥20 U/mL as seropositive. Mixed vaccine schedules demonstrated non-inferiority to standard schedules, with no significant differences in immunogenic response. Safety profiles were comparable across all groups, with no increased incidence of serious adverse events or intussusception.ConclusionThe study confirms that mixed rotavirus vaccine schedules are non-inferior to standard RV1 and RV5 regimens in terms of immunogenicity and safety. This finding supports the flexibility of rotavirus vaccination strategies, particularly in contexts of vaccine shortage or logistic constraints. These results contribute to the global effort to optimize rotavirus vaccination programs for broader and more effective pediatric coverage.Clinical trial registration: ClinicalTrials.gov, NCT02193061.
Yupingfeng polysaccharide promote the growth of chickens via regulating gut microbiota
Authors: Guan Yuling , Zheng Wendan , Bai Yu , Wu Bo 
Published: February 2024

IntroductionYupingfeng polysaccharide (YPF-P) is the main substance of alcohol deposition in Yupingfeng powder, which has many biological functions such as enhancing immunity, repairing intestinal barrier and enhancing antioxidant ability. This study employed in vitro growth-promoting drug feed additives and animal experiments to comprehensively evaluate the use of YPF-P in broiler production.MethodsA total of 1,296 151 days-old Qingyuan Partridge chickens were randomly divided into four groups with six replicates and 54 hens per replicate: the control group was fed basal diet, and the experimental groups were fed diets supplemented with 4 g/kg, 8 g/kg, and 12 g/kg YPF-P for 14 days. Broilers were weighed before and at the end of the experiment to calculate total weight gain (GW), average daily gain (ADG), and feed compensation. At the end of the experiment, six chickens from each group were randomly selected for subwing vein blood sampling, which was used to measure serum biochemical indicators GHRH, GH, and IGF-1 by ELISA method. Randomly select chickens from control group and 8 g/kg group for slaughter, and cecal contents were collected for 16S high-throughput sequencing.ResultsDietary supplementation of 8 g/kg YPF-P can significantly increase the final body weight, total weight gain, average daily gain and decrease the feed to gain ratio of chickens. During 151–165 days, serum IGF-1 concentrations increased significantly (p &lt; 0.05). There were no significant changes in serum GH concentration (p &gt; 0.05). In terms of gut microbiota, there was no significant difference between control group and test group in Shannon index and Simpson index. Compared with the control group,the addition of 8 g/kgYPF-P significantly increased the abundance of Firmicutes and significantly decreased the abundance of Bacteroides at the phylum level.At the genus level, the relative abundance of unclassified_Oscillospiraceae was significantly increased and the unclassified_Muribaculaceae, uncultured_Bacteroidales_bacterium, Lactobacillus, Alloprevotella, Ligilactobacillus, Prevotellaceae_UCG_001, and unclassified_Atopobiaceae was significantly decreased.ConclusionThe above results showed that adding 8 mg/kg of YPF-P could increase the average daily gain of Qingyuan Partridge chickens, reduce the ratio of feed to meat, and affect the distribution proportion of intestinal microflora in chickens to some extent.
El Uso de Herramientas de Simulación para la Enseñanza de Asignaturas Teóricas en Educación Superior
Authors: Cortés Hernández Lizeth Dayane , Villarreal Solano Ariel Yezid , Hernández Camelo Glenn Elmer 
Published: February 2024

Este artículo investigativo analizó el uso de herramientas de simulación en la enseñanza de asignaturas teóricas en el ámbito de la educación superior, El estudio se realizó específicamente en el programa de Tecnología en Electricidad Industrial de las Unidades Tecnológicas de Santander en Bucaramanga, Colombia. Se inicia con una revisión de antecedentes bibliográficos que validan el tema y se complementó con una encuesta realizada a la población del programa académico. Con lo anterior se confirmó la necesidad de aplicar la simulación en ciertas asignaturas y mediante el análisis de estudios de mortalidad realizados en el programa, se detectó que la asignatura de circuitos eléctricos era la que más necesitaba de dicha intervención. Al final, estos hallazgos son utilizados para respaldar la importancia de desarrollar un nuevo modelo didáctico el cual será un trabajo doctoral a realizarse en la Universidad UMECIT de Panamá por parte de los autores.
Identifikasi Komponen Harmonik di Selat Larantuka Berdasarkan Data Arus Time Series
Authors: Harmoko Faiza , Pranowo Widodo Setiyo , Malik Kurnia , Handoko Dadang 
Published: February 2024

Selat Larantuka merupakan salah satu selat sempit yang menghubungkan antara Laut Flores dan Laut Sawu. Perpindahan masa air dari Samudera Pasifik menuju Samudera Hindia, yang disebabkan oleh perbedaan ketinggian air laut berakibat arus dari Samudera Pasifik melintasi Selat Makasar menuju selatan, kemudian terbagi melewati selat-selat yang lebih kecil di perairan Bali hingga Nusa Tenggara Timur. Pola arus tersebut dipengaruhi keadaan perairan setempat yang dilewatinya, sehingga arus memiliki karakteristik yang unik pada masing-masing tempat. Selat Larantuka yang terhubung dengan Laut Sawu dimana Laut Sawu berhubungan langsung dengan Samudera Hindia, sehingga fenomena oseanografi mempengaruhi karakter arus di Selat Larantuka diantaranya adalah pasang surut dan internal wave yang terbentuk karena interaksi antara arus laut dalam yang berasal dari Samudera Hindia menuju Laut Flores melalui Laut Sawu dan Selat Larantuka . Arus pasut memiliki komponen harmonik seperti gaya pembangkitnya, namun terdapat perbedaan pada frekuensi dan fasa yang terbentuk. Komponen harmonik pasut dan arus pasut merupakan salah satu indikator dalam penentuan karakteristik suatu perairan. Tujuan dari penelitian ini adalah untuk memperoleh besaran komponen harmonik yang diturunkan dari arus di Selat Larantuka berdasarkan data survei Hidro Oseanografi Pushidrosal tahun 2019. Berdasarkan analisis harmonik pada studi ini diketahui bahwa karakteristik arus di Selat Larantuka dipengaruhi komponen harmonik signifikan akibat pengaruh gerakan bulan antara lain M4 kecepatan 0.04 m/detik fase 125,24º dan M8 kecepatan 0,05 m/detik fase 293,61° sedangkan yang dipengaruhi interaksi antara gaya gravitasi bulan dan matahari di perairan dangkal adalah MS4 dengan kecepatan 0,035 meter/detik fase 176,05 °.
Exploring Journalists’ Intentions Towards Digital Mobile Technologies
Authors: Demuyakor Dr. John , Boye-Doe Zillah 
Published: February 2024

In recent years, the use of digital mobile technologies for journalistic practice has gained much popularity among Ghanaian journalists. In this study, we explored three original Technology Acceptance Model (TAM) variables (perceived ease of use, perceived usefulness, and social influence) and two additional variables, (the cost of smartphones, and the cost of mobile data) to predict the relationship between the five variables, and journalists’ intention to use Digital Mobile Technologies (DMTs). A structured questionnaire was used to solicit data from 281 Ghanaian frontline journalists through an online survey. The respondents were selected by purposive sampling. Structural Equation Modelling analysis of the data showed that, as the cost of smartphones, and the cost of mobile data increases, journalists’ intention to use technology decreases in Ghana. Thus, mobile data and the cost of smartphones had a negative relationship with journalists’ intention to use DMTs. The testing of perceived ease of use, perceived usefulness, and social influence, however, reported a positive relationship with the use intention. The findings from this study have implications for policy change on the reduction of the prices of both mobile data and smartphones to enhance the use of DMTs among journalists in Ghana. Also, the findings from this study could be considered a template for the proper regulation of the use of DMTs for enhanced practice of journalism in Ghana and other developing countries.
Atlas Florae Europaeae notes, 34. Distributions and two conservation profiles of East European species of the Cytisus ratisbonensis group (Fabaceae)
Authors: Sennikov Alexander , Tikhomirov Valery 
Published: February 2024

The Cytisus ratisbonensis group (Fabaceae) includes small shrubs with attractive yellow flowers, used in ornamental cultivation. It is widely distributed in southern forest, forest steppe and steppe zones of Eastern Europe, both in the lowlands and low mountains. This group is notorious for its taxonomic complexity and difficulties in identification, which accounted for incongruent taxonomic treatments and common identification errors, and resulted in a poor understanding of the distribution areas. The increasing availability of herbarium collections and accumulation of human observations through digital resources require their critical taxonomic revision and update in order to provide reliable data for plant species mapping, conservation and analysis of distribution areas.
This paper describes a distributional dataset of East European species of the Cytisus ratisbonensis group, which was prepared for the pan-European grid mapping project, Atlas Florae Europaeae. The taxonomic revision includes seven species and two interspecific hybrids and is based on the critical evaluation of diagnostic characters, nomenclature and synonymy. The territorial scope of this study is Eastern Europe, but it also includes some data from Central Europe, the Caucasus and the neighbouring territories of Siberia and Kazakhstan, which are included in order to trace eastern and south-eastern limits of the species distributions and to establish reliable synonymy. We report 3699 native occurrence records included in the dataset; these records are based on major herbarium collections which are known to hold specimens from Eastern Europe (DNZ, KRA, KRAM, KW, LE, LW, LWKS, MHA, MSK, MSKH, MSKU, MW), complemented by selected specimens from other herbaria (BUNS, CSAU, H, NNSU, NS, NSK, OXF, PVB, RWBG, TUL). The herbarium collections were examined largely de visu, but partly online. Besides the herbarium specimens, recognisable photographs documenting human observations on online platforms (florafauna.by, iNaturalist, Plantarium, UkrBIN) were also examined and included. All specimen records are accompanied with textual data and georeferences, which were produced for this dataset. Point and contour distribution maps are created for each accepted species. According to the distributional data, the Cytisus ratisbonensis group may be classified as temperate lowland and steppic in Eastern Europe. Among European endemic shrubs, C. cinereus (as C. paczoskii) was assessed in 2017 as Near Threatened, whereas its new IUCN protection status is proposed as Least Concern because the new data demonstrated that its distribution area is much greater than previously believed. A species restricted to the Crimea, C. wulffii, is assessed here for the first time as Vulnerable because of its restricted area and small population size (criteria D1,2).
Öffentlichkeit und Presse in der Habsburgermonarchie
Authors: Melischek Gabriele , Seethaler Josef 
Published: February 2024

Der Beitrag gibt einen Überblick über die strukturelle Entwicklung der Presse in der Habsburgermonarchie. Der Zeitrahmen wird von jener gesellschaftlichen Funktion der Medien bestimmt, die in der Aufklärung zukunftsweisend formuliert wurde und die in der Habsburgermonarchie – nach einem ersten, halbherzig zugelassenen Versuch während der Regierungszeit Joseph II. und einem kurzen Zwischenspiel in der blutig niedergeschlagenen Revolution des Jahres 1848 – erst seit Beginn der 1860er Jahre (wenn auch keineswegs frei von Behinderungen) realisiert werden konnte: die Herstellung einer allgemeinen, prinzipiell niemanden ausgrenzenden Öffentlichkeit für politische Themen und Prozesse. Dies setzt die Transparenz staatlichen Handelns und die Freiheit der Presse voraus. Öffentlichkeit wird somit zu einem intermediären Raum zwischen staatlicher Macht und den Bürgern, der zugleich Kommunikationsraum, Kontrollmechanismus und Ort politischer Legitimation ist. Diese Zusammenhänge philosophisch und staatsrechtlich begründet zu haben, ist eines der Verdienste der Aufklärung. In den Teilen der Habsburgermonarchie vollzog sich die Etablierung einer allgemeinen politischen Öffentlichkeit in unterschiedlichen Geschwindigkeiten und unterschiedlichem Ausmaß.
„Der Fürsten Reichtum sind die Herzen der Unterthanen.“ Ideen der Aufklärung und das Bild der Herrscher in der Laibacher Zeitung im letzten Jahrzehnt des 18. Jahrhunderts
Authors: Osvald Anja Urekar 
Published: February 2024

Der vorliegende Beitrag untersucht Repräsentationen von aufklärerischen Ideen und deren Vertretern sowie Bilder von Herrschern in dem deutschsprachigen Periodikum Laibacher Zeitung aus der Krain im letzten Jahrzehnt des 18. Jahrhunderts. Es werden Parallelen zwischen den Reformen Josephs II. und dem wirtschaftlichen Erfolg des Buchdruckers und Herausgebers der Laibacher Zeitung Ignaz Kleinmayr gezogen und die Repräsentation der damaligen absolutistischen Herrscher näher dargestellt. Im Mittelpunkt der Medialisierung stehen die Tugenden der Herrscher und die Sicherung der Naturrechte (auf Leben, Freiheit und Eigentum) der Bevölkerung, die im Motiv des Glückes immer wieder vorkommt. Die Herrscher werden als Verantwortliche für das Wohlergehen der Gesellschaft dargestellt, gleichzeitig bleibt ihre Darstellung aber einer idealisierten Feudalidee verhaftet.
Frauen im aufklärerischen Diskurs in der Laibacher Zeitung an der Wende vom 18. zum 19. Jahrhundert
Authors: Birk Matjaž 
Published: February 2024

Ausgehend von den an der Wende vom 18. zum 19. Jahrhundert in der Laibacher Zeitung veröffentlichten Artikeln werden im Beitrag mediale Konstruktionen der Geschlechter, mit dem Fokus auf weiblichen Figuren, beleuchtet. Im Mittelpunkt stehen strukturelle und potentielle funktionale Aspekte von Konstruktionen der Weiblichkeit, die zeigen, dass der Aufklärungsdiskus in dem auf die Frau bezogenen Mediatisierungssegment vielfältig in die Praxis umgesetzt wurde. Dabei wird weiblichen Mitgliedern aus dem Hause Habsburg eine besondere Rolle zugemessen. Sie fungieren als Vorbildfiguren im Bereich der Bildung, indem sie sich als Gönnerinnen hervortun und mit gutem Beispiel im Umgang mit dem Aberglauben vorangehen. Auf die Bildung als auf Frauen bezogenes Betätigungsfeld folgen praktische (religiöse) Toleranz und Menschenfreundlichkeit bzw. humanitäre Tätigkeit, der das Prädikat geschlechtsspezifischer Haltung zuteil wird. Im humanitären Bereich treten in den Vordergrund Bürgerinnen, womit Frauen letztendlich als Katalysatorinnen gesellschaftlichen Fortschritts zum Vorschein kommen. Dabei wird neben dem monarchischen und heimatbezogenen zweckmäßig auch internationaler sozio-kultureller Kontext bemüht und außer ein sachlichen Texten auch literarische Texte in Versen eingesetzt. Unter dem Einfluss peripherer Raumspezifika paart sich der Aufklärungsdiskurs in Bereichen der Bildung und Menschenfreundlichkeit mit dem christlichen, was in der frauenbezogenen Repräsentation des Bildungs-, und im damit zusammenhängenden Kunstbereich, stellenweise zur Abkehr von progressiver Weiblichkeitsrepräsentation führt. Um identitätsstiftende Vorstellung von herrschenden Geschlechterpositionen und geschlechtlicher Machtverteilung nicht aus dem Blickwinkel zu verlieren, wird die Repräsentation der Frau unvermittelt in patriarchalischen Diskurs eingebettet, der vor misogynen Stereotypen keinen Halt macht, zugleich aber auch auf kritischen Fingerzeig auf Selbstherrlichkeit einzelner Männer-Gemeinschaften nicht zu verzichten bereit ist.