bluuebunny/crossref_metadata_2025_split huggingface dataset:
A Numerical Study on the Effects of Taiwan Topography on a Convective Line during the Mei-Yu Season
Authors: Wang Chung-Chieh , Chen George Tai-Jen , Chen Tzu-Chin , Tsuboki Kazuhisa 
Published: November 2005

Abstract
During the morning hours on 23 May 2002, a convective line associated with a mei-yu front brought heavy rainfall along the coast of central Taiwan under favorable synoptic conditions of warm air advection and large convective available potential energy (CAPE) of over 3000 m2 s−2. Doppler radar observations indicated that deep convection was organized into a linear shape with a northeast–southwest orientation along the front about 70 km offshore from Taiwan over the northern Taiwan Strait. The system then moved toward Taiwan at a slow speed of about 4 m s−1. In the present study, the effects of Taiwan topography on this convective line and subsequent rainfall distribution were investigated through numerical modeling using the Nagoya University Cloud-Resolving Storm Simulator (CReSS) at a 2-km horizontal grid size. Experiments with different terrain heights of Taiwan, including full terrain (FTRN), half terrain (HTRN), and no terrain (NTRN), were performed. The control run using full-terrain and cold rain explicit microphysics realistically reproduced the evolution of the convective line and the associated weather with many fine details.
Two low-level convergence zones were found to be crucial in the development of this convective line and the subsequent rainfall distribution over Taiwan. The first was along the mei-yu front and forced mainly by the front, but was terrain enhanced off the northwestern coast of Taiwan due to the blocking of air on the windward side of the Central Mountain Range (CMR). After formation, convective cells along this zone propagated southeastward and produced rainfall over the northwestern coast. As the front moved closer to Taiwan, a second arc-shaped convergence zone with a nearly north–south orientation along about 120°E formed ahead of the front between the prevailing flow and near-surface offshore flow induced by the blocking. This second zone was terrain induced, and convection initiated near its northern end was found to be responsible for the rainfall maximum observed near the coast of central Taiwan. Its intensity and position were highly sensitive to terrain height. In the HTRN run where the terrain was reduced by half, a weaker zone closer to the CMR (by about 50 km) was produced, and the rain fell mostly over the windward slope of the terrain instead of over the coastal plain. When the terrain was removed in the NTRN run, no such zone with the correct orientation formed. It was also found that the frontal movement near northern Taiwan was slightly delayed with the presence of terrain, and this affected the timing and distribution of local rainfall during the later stages of this event.
Impacts of Air–Sea Interaction on Tropical Cyclone Track and Intensity
Authors: Wu Liguang , Wang Bin , Braun Scott A. 
Published: November 2005

Abstract
While the previous studies of the impacts of air–sea interaction on tropical cyclones (TCs) generally agree on significant reduction in intensity and little change in track, they did not further explore the relative roles of the weak symmetric and strong asymmetric sea surface temperature (SST) anomalies relative to the TC center. These issues are investigated numerically with a coupled hurricane–ocean model in this study.
Despite the relatively small magnitude compared to the asymmetric component of the resulting cooling, the symmetric cooling plays a decisive role in weakening TC intensity. A likely reason is that the symmetric cooling directly reduces the TC intensity, while the asymmetric cooling affects the intensity through the resulting TC asymmetries, which are mainly confined to the lower boundary and much weaker than those resulting from large-scale environmental influences.
The differences in TC tracks between the coupled and fixed SST experiments are generally small because of the competing processes associated with the changes in TC asymmetries and the beta drift induced by air–sea interaction. The symmetric component of the SST drop weakens the TC intensity and outer strength, leading to a more northward beta drift. On the other hand, since the asymmetric component of the SST cooling is negative in the rear and positive in the front of a TC in the coupled experiments, the enhanced diabatic heating is on the southern side of a westward-moving TC, tending to shift the TC southward. In the coupled model the westward TCs with relatively weak (strong) outer strength tend to turn to the north (south) of the corresponding TCs without air–sea interaction.
Incorporating Misclassification Error in Skill Assessment
Authors: Briggs William , Pocernich Matt , Ruppert David 
Published: November 2005

Abstract
It is desirable to account for misclassification error of meteorological observations so that the true skill of the forecast can be assessed. Errors in observations can occur, among other places, in pilot reports of icing and in tornado spotting. Not accounting for misclassification error gives a misleading picture of the forecast’s true performance. An extension to the climate skill score test developed in Briggs and Ruppert is presented to account for possible misclassification error of the meteorological observation. This extension supposes a statistical misclassification-error model where “gold standard” data, or expert opinion, is available to characterize the misclassification-error characteristics of the observation. These model parameters are then inserted into the Briggs and Ruppert skill score for which a statistical test of significance can be performed.
A Cloud-Base Quasi-Balance Constraint for Parameterized Convection: Application to the Kain–Fritsch Cumulus Scheme
Authors: Ridout James A. , Jin Yi , Liou Chi-Sann 
Published: November 2005

Abstract
A quasi balance with respect to parcel buoyancy at cloud base between destabilizing processes and convection is imposed as a constraint on convective cloud-base mass flux in a modified version of the Kain–Fritsch cumulus parameterization. Supporting evidence is presented for this treatment, showing a cloud-base quasi balance (CBQ) on a time scale of approximately 1–3 h in explicit simulations of deep convection over the U.S. Great Plains and over the tropical Pacific Ocean with the Naval Research Laboratory’s Coupled Ocean/Atmosphere Mesoscale Prediction System (COAMPS).1 With the exception of the smaller of two convective events in the Great Plains simulation, a CBQ is still observed upon restriction of the data analysis to instances where the available buoyant energy (ABE) exceeds a threshold value of 1000 J kg−1. This observation is consistent with the view that feedbacks between convection and cloud-base parcel buoyancy can control the rate of convection on shorter time scales than those associated with the elimination of buoyant energy and supports the addition of a CBQ constraint to the Kain–Fritsch mass-flux closure.
Tests of the modified Kain–Fritsch scheme in single-column-model simulations based on the explicit three-dimensional simulations show a significant improvement in the representation of the main convective episodes, with a greater amount of convective rainfall. The performance of the scheme in COAMPS precipitation forecast experiments over the continental United States is also investigated. Improvements are obtained with the modified scheme in skill scores for middle to high rainfall rates.
Origin and Propagation of a Disturbance Associated with an African Easterly Wave as a Precursor of Hurricane Alberto (2000)
Authors: Lin Yuh-Lang , Robertson Katie E. , Hill Christopher M. 
Published: November 2005

Abstract
In this study, it is proposed that mesoscale convective complexes (MCCs) and a mesovortex (MV) were embedded within a wavelike disturbance over North Africa that led to the genesis of Hurricane Alberto (2000). The wavelike disturbance observed may be classified as an African easterly wave (AEW). Based on the cloud-top area and brightness values observed from infrared satellite data, four genesis and three lysis stages are identified within a cycle of moist convection associated with the pre-Alberto disturbance. The availability of water vapor is the most essential factor controlling the convective cycle of the pre-Alberto disturbance over the African continent. The presence of significant topography also contributes to the generation or decay of the associated MCCs through regulation of the water vapor supply. Further analysis of Meteosat satellite imagery reveals that the incipient disturbances for 23 of 34 eastern Atlantic tropical cyclones originated from the Ethiopian highlands (EH) region during the period of 1990–2001.
The pre-Alberto disturbance was found to have exhibited characteristics of an AEW. At the EH, there existed two modes of disturbance development: a stationary mode and a propagating mode. The stationary mode corresponded with the generation of moist convection over the EH triggered by diurnally variant sensible heating, while the propagating mode corresponded with the generation and propagation of MVs and mesoscale convective systems (MCSs) from the lee side of the EH over a period of about 2 to 3 days. These components of the disturbance propagated westward together within an AEW train at an average speed of 11.6 m s−1. The average wavelength was roughly estimated to be about 2200 km.
To prove that disturbances generated at the EH are indeed AEWs, the NCAR Regional Climate Model Version 3.0 is adopted to simulate the event. The simulated fields showed that both the propagating wave and stationary mountain wave modes were present, the convection was generated over the EH, and the pre-Alberto disturbance was generated near the lee of the EH. In addition, the convective cycle detected from NCEP reanalysis data was also reflected in the simulated fields. The simulated AEW possesses similar wave characteristics as the observed pre-Alberto disturbance.
Stability Analysis of Geostrophic Adjustment on Hexagonal Grids for Regions with Variable Depth
Authors: Torsvik Tomas , Thiem Øyvind , Berntsen Jarle 
Published: November 2005

Abstract
Hexagonal grids have been used in a number of numerical studies, and especially in relation to atmospheric models. Recent studies have suggested that ocean circulation models may also benefit from the use of hexagonal grids. These grids tend to induce less systematic errors and have better horizontal isotropy properties than traditional square grid schemes. If hexagonal grids are to be applied in ocean models, a number of features that are characteristic of ocean circulation problems need to be attended to.
The topography of the ocean basin is an important feature in most ocean models. Ocean modelers can experience instabilities due to depth variations. In the present paper, analysis of the propagation matrix for the spatially discretized system is used to explain unphysical growth of the numerical solutions of the linear shallow water equations when using hexagonal grids over domains with variable depth. It is shown that a suitable weighting of the Coriolis terms may give an energy-conserving and stable numerical scheme.
Tension-Band Wiring for Fractures of the Fifth Metatarsal Located in the Junction of the Proximal Metaphysis and Diaphysis
Authors: Sarimo Janne , Rantanen Jussi , Orava Sakari , Alanen Jouko 
Published: November 2005

Background Fractures of the proximal fifth metatarsal, other than those involving the tuberosity, have a tendency to delayed union or even nonunion. Hypothesis Tension-band wire technique is a good alternative in treating fractures of the fifth metatarsal located in the proximal junction of the metaphysis and the diaphysis. Study Design Case series; level of evidence, 4. Methods Between 1996 and 2001, a total of 27 cases of proximal metaphysial/diaphysial fractures of the fifth metatarsal were treated with tension-band wiring. All of the patients had undergone prior unsuccessful nonoperative or operative treatment. The mean delay from the diagnosis of the fracture to the final operative procedure was 19.5 weeks (range, 6-48 weeks). Results The mean length of follow-up was 35 months (range, 12-70 months). All patients were able to return to their prior levels of activity. The mean time for union as shown on radiographs was 12.8 weeks, and the return to full activity took 8 to 20 weeks (mean, 14.7 weeks). There were no delayed unions, nonunions, or refractures during the follow-up. Conclusion The tension-band wire technique seems to give good results in the treatment of proximal metaphysial/diaphysial fractures of the fifth metatarsal in cases of primary unsuccessful nonoperative treatment or primary unsuccessful intramedullary screw fixation.
Glenohumeral Range of Motion Deficits and Posterior Shoulder Tightness in Throwers with Pathologic Internal Impingement
Authors: Myers Joseph B. , Laudner Kevin G. , Pasquale Maria R. , Bradley James P. , Lephart Scott M. 
Published: November 2005

Background Alterations in glenohumeral range of motion, including increased posterior shoulder tightness and glenohumeral internal rotation deficit that exceeds the accompanying external rotation gain, are suggested contributors to throwing-related shoulder injuries such as pathologic internal impingement. Yet these contributors have not been identified in throwers with internal impingement. Hypothesis Throwers with pathologic internal impingement will exhibit significantly increased posterior shoulder tightness and glenohumeral internal rotation deficit without significantly increased external rotation gain. Study Design Case control study; Level of evidence, 3. Methods Eleven throwing athletes with pathologic internal impingement diagnosed using both clinical examination and a magnetic resonance arthrogram were demographically matched with 11 control throwers who had no history of upper extremity injury. Passive glenohumeral internal and external rotation were measured bilaterally with standard goniometry at 90 ° of humeral abduction and elbow flexion. Bilateral differences in glenohumeral range of motion were used to calculate glenohumeral internal rotation deficit and external rotation gain. Posterior shoulder tightness was quantified as the bilateral difference in passive shoulder horizontal adduction with the scapula retracted and the shoulder at 90 ° of elevation. Comparisons were made between groups with dependent t-tests (P< .05). Results The throwing athletes with internal impingement demonstrated signif icantly greater glenohumeral internal rotation deficit (P= .03) and posterior shoulder tightness (P= .03) compared with the control subjects. No significant differences were observed in external rotation gain between groups (P= .16). Clinical Relevance These findings could indicate that a tightening of the posterior elements of the shoulder (capsule, rotator cuff) may contribute to impingement. The results suggest that management should include stretching to restore flexibility to the posterior shoulder.
Injuries in Team Sport Tournaments during the 2004 Olympic Games
Authors: Junge Astrid , Langevoort Gijs , Pipe Andrew , Peytavin Annie , Wong Fook , Mountjoy Margo , Beltrami Gianfranco , Terrell Robert , Holzgraefe Manfred , Charles Richard , Dvorak Jiri 
Published: November 2005

Background Several authors have analyzed the incidence of injuries in a given sport, but only a few have examined the exposure-related incidence of injuries in different types of sports using the same methodology. Purpose Analysis of the incidence, circumstances, and characteristics of injuries in different team sports during the 2004 Olympic Games. Study Design Cohort study; Level of evidence, 2. Methods During the 2004 Olympic Games, injuries in 14 team sport tournaments (men's and women's soccer, men's and women's handball, men's and women's basketball, men's and women's field hockey, baseball, softball, men's and women's water polo, and men's and women's volleyball) were analyzed. After each match, the physician of the participating teams or the official medical representative of the sport completed a standardized injury report form. The mean response rate was 93%. Results A total of 377 injuries were reported from 456 matches, an incidence of 0.8 injuries per match (95% confidence interval, 0.75-0.91) or 54 injuries per 1000 player matches (95% confidence interval, 49-60). Half of all injuries affected the lower extremity; 24% involved the head or neck. The most prevalent diagnoses were head contusion and ankle sprain. On average, 78% of injuries were caused by contact with another player. However, a significantly higher percentage of noncontact (57%) versus contact injuries (37%) was expected to prevent the player from participating in his or her sport. Significantly more injuries in male players (46%) versus female players (35%) were expected to result in absence from match or training. The incidence, diagnosis, and causes of injuries differed substantially between the team sports. Conclusion The risk of injury in different team sports can be compared using standardized methodology. Even if the incidence and characteristics of injuries are not identical in all sports, prevention of injury and promotion of fair play are relevant topics for almost all team sports.
Aplastic Anemia: Management of Adult Patients
Authors: Maciejewski Jaroslaw P. , Risitano Antonio M. 
Published: November 2005

Abstract
The primary therapeutic approach to acquired aplastic anemia (AA) in older adults differs from the primary approach used in children and younger adults because in the former group, the results of allogeneic bone marrow transplantation (BMT) are less favorable. With increasing age of the patients, immunosuppressive therapy with antithymocyte globulin (ATG) and cyclosporine (CsA) constitutes the primary treatment option and may be better than BMT. There are very few clinical clues as to the selection of patients likely to respond to immunosuppression. Repeated ATG/CsA cycles are often used as salvage regimens, but in refractory patients BMT may be the best treatment option, as the prognosis for non-responders is poor without definitive treatment. Conservative therapy such as intense immunosuppression is associated with a high relapse rate but does not impact the survival and overall prognosis. The inability to eliminate autoimmune T cell clones using current therapeutic strategies suggests that prolonged immunosuppressive maintenance therapy may be needed for a substantial proportion of patients. Late clonal complications of conservatively treated patients include evolution to myelodysplasia and paroxysmal nocturnal hemoglobinuria and may develop in 20% of the patients. However, BMT also has several sequelae including an increased frequency of solid tumors. Novel immunosuppressive and immunomodulatory agents and constantly improving results of allogeneic BMT will further improve the survival rate of adult patients with AA.
Treatment of Philadelphia Chromosome–Positive Acute Lymphoblastic Leukemia
Authors: Ottmann Oliver G. , Wassmann Barbara 
Published: November 2005

AbstractPhiladelphia chromosome positive (Ph+) acute lymphoblastic leukemia (ALL) includes at least one-quarter of all adults with ALL. Until recently, conventional chemotherapy programs that have been effective in other precursor B-cell ALL cases have been unable to cure patients with this diagnosis. Allogeneic stem cell transplantation early in first remission has been the recommended therapy. The availability of imatinib mesylate and other tyrosine kinase inhibitors and small molecules that affect the BCR/ABL signaling pathways may be changing the treatment paradigm and the prognosis for these patients. The results from clinical trials using imatinib in the frontline setting and in relapsed patients as well as preliminary experience treating imatinib-resistant Ph+ ALL will be described.
Acute Lymphoblastic Leukemia: Older Patients and Newer Drugs
Authors: Larson Richard A. 
Published: November 2005

AbstractAlthough the median age for adults with acute lymphoblastic leukemia (ALL) is older than 60 years, relatively few of these patients have been enrolled on prospective clinical trials. The presence of coexisting medical disorders and unfavorable cytogenetic and biological characteristics within this population presents considerable challenges for successful treatment using conventional chemotherapy programs. Selected patients have achieved remission and long-term survival following intensive chemotherapy. Preliminary data using several new agents that have shown promise for patients with ALL are described.
New Strategies for the Treatment of Acute Myeloid Leukemia Including Antibodies and Other Novel Agents
Authors: Tallman Martin S. 
Published: November 2005

AbstractThe prognosis for younger adults (≤ 55–60 years) with acute myeloid leukemia (AML) has improved during the last four decades. However, there has been little progress in the treatment of older adults. This disappointing observation is important because the median age of patients with AML is about 70 years. Approximately 60%–80% of younger adults with AML achieve complete remission (CR) with the cytotoxic agents cytarabine and an anthracycline such as daunorubicin or idarubicin or the anthracenedione mitoxantrone. However, only 30%–40% of such patients are alive and disease-free at 5 years. Among older adults, CR is achieved in 40%–55%, but there are very few long-term survivors. Many studies have evaluated the impact of alternative doses and schedules, as well as additional cytotoxic drugs, on the prognosis for this group of patients. The outcome has not improved substantially beyond that achieved with conventional doses of an anthracycline and cytarabine followed by high-dose cytarabine consolidation.Several factors identified at diagnosis can predict outcome. The most important of these is the karyotype of the leukemic cells. Another critical factor is the presence of transmembrane transporter proteins, which confer multidrug resistance and mutations in or overexpression of specific genes such as WT1, C/EBPα, BAX, and BCL-2/BAX ratio, BAALC, EVI1, KIT and FLT3. The development of specific agents directed at gene mutations, signal transduction pathways and unique cell surface antigens provide the foundation for new therapeutic strategies. Such agents include the immunoconjugate gemtuzumab ozogamicin, multidrug resistance inhibitors, farnesyltransferase inhibitors, histone deacetylase and proteosome inhibitors, antiangiogenesis agents, FLT3 inhibitors, apoptosis inhibitors, and nucleoside analogs. All of these agents can potentially address the heterogeneous abnormalities in AML and significantly improve the outcome for patients.