bluuebunny/crossref_metadata_2025_split huggingface dataset:
Prediction of the Candida antarctica Lipase A Protein Structure by Comparative Modeling and Site‐Directed Mutagenesis.
Authors: Kasrayan Alex , Bocola Marco , Sandstroem Anders G. , Laven Gaston , Baeckvall Jan‐E. 
Published: October 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Total Synthesis of Potent Antifungal Marine Bisoxazole Natural Products Bengazoles A (Ia) and B (Ib).
Authors: Bull James A. , Balskus Emily P. , Horan Richard A. J. , Langner Martin , Ley Steven V. 
Published: October 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Synthesis of a Novel Sphingosine Kinase Inhibitor (‐)‐F‐12509A and Determination of Its Absolute Configuration.
Authors: Maezawa Nobuhiro , Furuichi Noriyuki , Tsuchikawa Hiroshi , Katsumura Shigeo 
Published: October 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Antitumor Anthraquinones from an Endophytic Actinomycete Micromonospora lupini sp. nov.
Authors: Igarashi Yasuhiro , Trujillo Martha E. , Martinez‐Molina Eustoquio , Yanase Saeko , Miyanaga Satoshi , Obata Takamasa , Sakurai Hiroaki , Saiki Ikuo , Fujita Tsuyoshi , Furumai Tamotsu 
Published: October 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
New Constituent from Podocarpus macrophyllus var. macrophyllus Shows Antityrosinase Effect and Regulates Tyrosinase‐Related Proteins and nRNA in Human Epidermal Melanocytes.
Authors: Cheng Kur‐Ta , Hsu Feng‐Lin , Chen Shih‐Hui , Hsieh Peng‐Ke , Huang Hsu‐Shan , Lee Ching‐Kuo , Lee Mei‐Hsien 
Published: October 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Synthesis of Novel Phosphorylated Daidzein Derivatives and ESI Investigation on Their Non‐Covalent Complexes with Lysozyme.
Authors: Chen Xiao‐Lan , Shi Xiao‐Na , Qu Ling‐Bo , Yuan Jin‐Wei , Lu Jian‐Sha , Zhao Yu‐Fen 
Published: October 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Cyclic Ureas as Novel Building Blocks for Bent‐Core Liquid Crystals.
Authors: Glettner Benjamin , Hein Sara , Reddy R. Amaranatha , Baumeister Ute , Tschierske Carsten 
Published: October 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Novel Potent Antimitotic Heterocyclic Ketones: Synthesis, Antiproliferative Activity, and Structure—Activity Relationships.
Authors: Hu Laixing , Jiang Jian‐dong , Qu Jinrong , Li Yan , Jin Jie , Li Zhuo‐rong , Boykin David W. 
Published: October 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Efficient Catalyst Reuse by Simple Dissolution in Non‐Conventional Media.
Authors: Afonso Carlos A. M. , Branco Luis C. , Candeias Nuno R. , Gois Pedro M. P. , Lourenco Nuno M. T. , Mateus Nuno M. M. , Rosa Joao N. 
Published: October 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Basis for Design and Development of Platinum(IV) Anticancer Complexes
Authors: Hall Matthew D. , Mellor Howard R. , Callaghan Richard , Hambley Trevor W. 
Published: October 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Preventing UV‐Light Damage of Light‐Sensitive Materials Using a Highly Protective UV‐Absorbing Coating
Authors: Zayat Marcos , Garcia‐Parejo Pilar , Levy David 
Published: October 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
One Dimensional Nanostructured Materials
Authors: Kuchibhatla Satyanarayana V. N. T. , Karakoti A. S. , Bera Debasis , Seal S. 
Published: October 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Benzo‐1,2‐, Benzo‐1,4‐, Naphtho‐1,2‐, and Naphtho‐1,4‐quinone Imines and Diimines
Authors: Carreno M. C. , Ribagorda M. 
Published: October 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Anthra‐9,10‐quinones, Anthra‐1,2‐quinones, Anthra‐1,4‐quinones, Anthra‐2,9‐quinones, and Their Higher Fused Analogues
Authors: Krohn K. , Boker N. 
Published: October 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Microemulsions as Microreactors in Physical Organic Chemistry
Authors: Garcia‐Rio Luis , Leis J. Ramon , Mejuto Juan Carlos , Perez‐Lorenzo Moises 
Published: October 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Kinetics and Mechanism of Ozonized Oxidation of Ketones
Authors: Zimin Yu. S. , Monakov Yu. B. , Komissarov V. D. 
Published: October 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Sorption Isotherms: Physical Bases, Modeling and Measurement
Authors: Limousin G. , Gaudet J.‐P. , Charlet L. , Szenknect S. , Barthes V. , Krimissa M. 
Published: October 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Exploring Basic Chemical Concepts with the Quantum Theory of Atoms in Molecules
Authors: Mosquera Ricardo A. , Moa Maria J. Gonzalez , Grana Ana M. , Mandado Marcos , Vila Antonio 
Published: October 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Chest Pain on Exercise Treadmill Test Predicts Future Cardiac Hospitalizations
Authors: Ho P. Michael , Rumsfeld John S. , Peterson Pamela N. , Masoudi Frederick A. , Strunk Adam , Ross Colleen , Lyons Ella E. , Smith S. Scott , Lauer Michael S. , Magid David J. 
Published: October 2007

AbstractBackground:Patients often have chest pain during exercise treadmill testing (ETT). However, the evidence supporting chest pain as an independent adverse prognostic factor during ETT has been inconsistent. The objective of this study was to determine the importance of chest pain during ETT in predicting future nonfatal cardiac hospitalizations.Methods:This was a prospective cohort study of all patients undergoing ETT between July 2001 and June 2004 in a large managed care organization. The primary outcome of interest was nonfatal cardiac hospitalizations including myocardial infarction and unstable angina. Multivariable Cox proportional hazards regression assessed the independent association between chest pain during ETT and subsequent nonfatal cardiac hospitalizations, adjusting patient, clinical and other treadmill variables.Results:Of the 8,459 patients undergoing ETT, 697 (8.2%) patients had chest pain during the test. Patients with chest pain during ETT had more nonfatal cardiac hospitalizations compared to patients without chest pain (11.9% vs. 2.6%; p < 0.0001). In multivariable Cox regression analysis, patients with chest pain during ETT remained at significantly increased risk of nonfatal cardiac hospitalizations (HR 3.44; 95% CI 2.60–4.56). The association between chest pain and adverse outcomes was consistent among prespecified subgroups including patients without ST‐segment changes and with good functional capacity on ETT.Conclusions:Chest pain during ETT, even without ECG changes, predicts subsequent cardiac hospitalizations. Future studies should evaluate whether aggressive management of such patients can prevent subsequent hospitalizations. Copyright © 2007 Wiley Periodicals, Inc.
Three‐dimensional tissue cytometer based on high‐speed multiphoton microscopy
Authors: Kim Ki Hean , Ragan Timothy , Previte Michael J. R. , Bahlmann Karsten , Harley Brendan A. , Wiktor‐Brown Dominika M. , Stitt Molly S. , Hendricks Carrie A. , Almeida Karen H. , Engelward Bevin P. , So Peter T. C. 
Published: October 2007

AbstractImage cytometry technology has been extended to 3D based on high‐speed multiphoton microscopy. This technique allows in situ study of tissue specimens preserving important cell–cell and cell–extracellular matrix interactions. The imaging system was based on high‐speed multiphoton microscopy (HSMPM) for 3D deep tissue imaging with minimal photodamage. Using appropriate fluorescent labels and a specimen translation stage, we could quantify cellular and biochemical states of tissues in a high throughput manner. This approach could assay tissue structures with subcellular resolution down to a few hundred micrometers deep. Its throughput could be quantified by the rate of volume imaging: 1.45 mm3/h with high resolution. For a tissue containing tightly packed, stratified cellular layers, this rate corresponded to sampling about 200 cells/s. We characterized the performance of 3D tissue cytometer by quantifying rare cell populations in 2D and 3D specimens in vitro. The measured population ratios, which were obtained by image analysis, agreed well with the expected ratios down to the ratio of 1/105. This technology was also applied to the detection of rare skin structures based on endogenous fluorophores. Sebaceous glands and a cell cluster at the base of a hair follicle were identified. Finally, the 3D tissue cytometer was applied to detect rare cells that had undergone homologous mitotic recombination in a novel transgenic mouse model, where recombination events could result in the expression of enhanced yellow fluorescent protein in the cells. 3D tissue cytometry based on HSMPM demonstrated its screening capability with high sensitivity and showed the possibility of studying cellular and biochemical states in tissues in situ. This technique will significantly expand the scope of cytometric studies to the biomedical problems where spatial and chemical relationships between cells and their tissue environments are important. © 2007 International Society for Analytical Cytology.
Flow cytometric quantitation of opsonophagocytosis and intracellular killing of Candida albicans using a whole blood microassay
Authors: Pattanapanyasat Kovit , Sukapirom Kasama , Tachavanich Kalaya , Kaewmoon Sakorn 
Published: October 2007

AbstractFlow cytometric assays for quantifying polymorphonuclear leucocyte (PMN) function involve peripheral blood fractionation methods. However, most are of limited use for conditions like pediatrics and thalassemia, as they may require large blood volumes or complicated by red blood cell contamination. In whole blood assay, 500‐μl aliquots of normal or thalassemic whole blood were incubated with bis‐carboxyethyl‐carboxyfluorescein pentaacetoxymethylester (BCECF‐AM)‐labeled Candida albicans cells and phycoerythrin‐conjugated anti‐CD13 monoclonal antibody for PMNs. Phagocytosis was quantitated by gating on CD13 label PMNs and determining the frequency of phagocytosed yeast using flow cytometry. The killing activity was quantitated by estimating the number of viable fluorescence retaining yeast cells liberated following lysis of PMNs. In normal control or thalassemia samples, nonphagocytosed yeast and PMNs with or without phagocytosed yeast were readily distinguished by two‐color dot plot, permitting phagocytosis estimates. Viable and nonviable yeast killed by whole blood PMNs were distinguished by side scatter and fluorescence, permitting killing estimates. The patterns seen using whole blood was similar to that seen with fractionated PMNs. Data from thalassemia patients showed similar opsonophagocytosis but slightly decreased intracellular killing of yeast cells when compared with normal subjects. This assay provides an alternative method to assess PMN function in small blood samples, which could be especially useful in conditions like thalassemia and pediatric patients. © 2007 International Society for Analytical Cytology
Growth of Aquincola tertiaricarbonis L108 on tert‐Butyl Alcohol Leads to the Induction of a Phthalate Dioxygenase‐related Protein and its Associated Oxidoreductase Subunit
Authors: Schäfer F. , Breuer U. , Benndorf D. , von Bergen M. , Harms H. , Müller R. H. 
Published: October 2007

AbstractThe microbial degradation of tert‐butyl alcohol (TBA), an important environmental pollutant and an intermediate in the degradation of methyl tert‐butyl ether (MTBE), was proposed to involve a monooxygenase for the initial oxidation of TBA, but up to now a specific enzyme with that activity has not been described except the well‐known AlkB for the Gram‐positive strain Mycobacterium austroafricanum IFP2012 (Lopez Ferreira et al., Appl. Microbiol. Biotechnol. 2007, 75, 909–919). In the course of our studies of the MTBE pathway, the proteome patterns in one‐ and two‐dimensional gels of Aquincola tertiaricarbonis L108 which was grown on lactate, on hydroxyisobutyrate (2‐HIBA) and TBA, were compared. A protein of about 55 kDa was detected after growth on TBA and 2‐HIBA, which, after mass spectrometric analysis of the tryptic digested peptides, was assigned with a high score to phthalate dioxygenase. Sequence analysis of PCR products obtained with primers derived from the amino acid sequences in the above peptides supported the assignment to the hydroxylase subunit of phthalate dioxygenase‐like proteins by covering 96.7 % of a corresponding gene from Methylibium petroleiphilum PM1. The conserved amino acid motifs ‐R‐x12‐CxHRxxxLxxG‐x8‐CxYHR‐x6‐G‐ for the Rieske [2Fe‐2S] binding domain and (‐D/E)xxxDxxHxxxxH‐ for the mononuclear iron binding domain were found. A second protein of about 38 kDa was detected after growth on TBA with a lower score and attributed to a putative iron‐sulfur oxidoreductase subunit. Primers derived from the peptides resulted in an amplicon, which covered 75.7 % of a corresponding gene from M. petroleiphilum PM1. Conserved motifs ‐RxYSL‐x20‐22‐RGGS‐ for FMN binding and ‐GGIGxTPxxxM‐ for NAD binding were detected, which suggests that this protein is the small subunit of a two‐component phthalate dioxygenase‐like enzyme typically containing FMN. Dioxygenase‐related enzymes are known to catalyze also monooxygenase reactions (see e.g. Zhou et al. J. Bacteriol. 2002, 184, 1547–1555), which makes it likely that the two proteins induced in the presence of TBA are involved in TBA oxidation.
Elimination of Endocrine Disrupting Chemicals using White Rot Fungi and their Lignin Modifying Enzymes: A Review
Authors: Cabana H. , Jones J. P. , Agathos S. N. 
Published: October 2007

AbstractThe ability of white rot fungi (WRF) and their lignin modifying enzymes (LMEs), i.e. laccase and lignin‐ and manganese‐dependent peroxidase, to treat endocrine disrupting chemicals (EDCs) is extensively reviewed in this paper. These chemicals cause adverse health effects by mimicking endogenous hormones in receiving organisms. The alkylphenolic EDCs nonylphenol, bisphenol A and triclosan, the phthalic acid esters dibutylphthalate, diethylphthalate and di‐(2‐ethylhexyl)phthalate, the natural estrogens estrone, 17β‐estradiol, estriol and 17α‐ethynylestradiol and the phytoestrogens genistein and β‐sitosterol have been shown to be eliminated by several fungi and LMEs. WRF have manifested a highly efficient removal of EDCs in aqueous media and soil matrices using both LME and non LME‐systems. The ligninolytic system of WRF could also be used for the elimination of several EDCs and the associated hormone‐mimicking activity. The transformation of EDCs by LMEs and WRF is supported by emerging knowledge on the physiology and biochemistry of these organisms and the biocatalytic properties of their enzymes. Due to field reaction conditions, which drastically differ from laboratory conditions, further efforts will have to be directed towards developing robust and reliable biotechnological processes for the treatment of EDC‐contaminated environmental matrices.
Bonding Form Analysis of Metals and Sulfur Fractionation in Methanol‐Grown Anaerobic Granular Sludge
Authors: van der Veen A. , Fermoso F. G. , Lens P. N. L. 
Published: October 2007

AbstractThis study investigates the metal and sulfur bonding form distribution in mesophilic (30 °C, pH 7) methanol‐grown anaerobic granular sludge from upflow anaerobic sludge bed reactors operating at an organic loading rate of 3.8 g CH3OH‐COD/L d. This was achieved by applying a modified Tessier sequential extraction scheme to investigate the metal bonding forms and a sequential extraction scheme for sulfur and simultaneously extracted metals to granular sludge samples of the reactors after 0, 22, 35 and 43 days of operation. Metals were also determined in the sulfur extracts. Co and Ni predominated in their oxidizable bonding forms, which increased together with the pseudo‐total content during reactor operation. An omission of Co and Ni from the influent led to only a minor decline of the pseudo‐total content in the sludge, mainly from the acid‐soluble fraction. The ratio of simultaneously extracted metals (Co, Fe, Mn, Ni) to acid‐volatile sulfides was lower than 1, indicating that the sludge contained sufficient sulfide to bind the metals as metal monosulfides. The bioavailability of metals in the methanol‐grown anaerobic granular sludge investigated is therefore mainly controlled by sulfide formation/dissolution.
Chemical composition of the essential oils from Eriocephalus africanus L. var. africanus populations growing in Spain
Authors: Merle Hugo , Verdeguer Mercedes , Blázquez M. Amparo , Boira Herminio 
Published: October 2007

AbstractEssential oils from the aerial parts of three Eriocephalus africanus L. var. africanus populations were analysed by means of GC–FID and GC–MS. Sixty‐one constituents were identified, representing more than 96% of the total oil composition. Artemisia ketone (56.46–56.58%), intermedeol (9.19–11.63%) and γ‐eudesmol (4.26–5.64%) were the main compounds. Application of the Pearson correlation coefficient showed high similarity between the nine samples analysed. Copyright © 2007 John Wiley & Sons, Ltd.
Comparison of different isolation methods of essential oil from Citrus fruits: cold pressing, hydrodistillation and microwave ‘dry’ distillation
Authors: Ferhat Mohamed A. , Meklati Brahim Y. , Chemat Farid 
Published: October 2007

AbstractTraditional hydrodistillation (HD), cold pressing (CP) and innovative microwave ‘dry’ distillation or microwave‐accelerated distillation (MAD) methods have been compared and evaluated for their effectiveness in the isolation of essential oil from fresh Citrus peels. The microwave method offers important advantages over traditional alternatives, viz. shorter extraction times (30 min vs. 3 h for hydrodistillation and 1 h for cold pressing); better yields (0.24% vs. 0.21% for HD and 0.05% for CP); environmental impact (energy cost is appreciably higher for performing HD and for mechanical motors (CP) than that required for rapid MAD extraction); cleaner features (as no residue generation and no water or solvent used); increases antimicrobial activities; and provides a more valuable essential oil (with high amounts of oxygenated compounds). It also offers the possibility for better reproduction of the natural aroma of the essential oil from Citrus fruit compared with CP, but more than the HD essential oil. Further, the microwave procedure yields essential oils that can be analysed or used directly without any clean‐up, solvent exchange or centrifugation steps. Scanning electron microscopy provides more evidence of the cleanness of microwave extraction, in contrast to the huge perforations on the external surface of the Citrus fruit peel in the case of conventional hydrodistillation. Finally, a mechanism of microwave ‘dry’ distillation is proposed and discussed. Copyright © 2007 John Wiley & Sons, Ltd.
The influence of cultivar on sensory profiles of fresh and processed strawberry fruits grown in Croatia
Authors: Bursać D. , Vahčić N. , Levaj B. , Dragović‐Uzelac V. , Biško A. 
Published: October 2007

AbstractSensory analysis was performed on fresh fruits, purées and low‐calorie jams prepared in laboratory conditions and under vacuum in three strawberry cultivars, Honeoye, Clery and NF 421, grown in Croatia. The purpose of this study was to characterize and compare the sensory quality of three different strawberry cultivars in fresh and processed strawberries. Quantitative descriptive analysis was used to establish sensory profiles. The results of investigation were presented by means of multivariate modelling methods, such as principal component analysis (PCA), which established that analysed sensory attributes can clearly be connected to different cultivars in fresh samples, purées and in all examined jams. The results established during this study on sensory profiles of fresh strawberries and their purées and jams represent a great contribution to the characterization of sensory profiles of these nutritionally high‐valued products. Copyright © 2007 John Wiley & Sons, Ltd.
Phenylbutanoid‐rich rhizome oil of Zingiber neesanum from Western Ghats, southern India
Authors: Sabulal Baby , Dan Mathew , J Anil John , Kurup Rajani , Chandrika Sreeja Purushothaman , George Varughese 
Published: October 2007

AbstractEssential oil from the rhizomes of Zingiber neesanum (Graham) Ramamoorthy from the Western Ghats region of southern India was isolated and characterized by GC and GC–MS. Oil constituents were identified by comparison of individual mass spectra with databases and the literature, linear retention indices and co‐injection. Sixty‐one constituents, comprising 97.4% of the oil, were identified. Phenylbutanoids, viz. (E)‐1‐(3′,4′‐dimethoxyphenyl)butadiene (31.1%), a potential antiinflammatory compound, and (E)‐1‐(3′,4′‐dimethoxyphenyl)but‐1‐ene (23.1%) were isolated from the oil by prep. TLC, characterized by IR, UV, 1H‐NMR and MS and quantified by external standardization. (E)‐β‐ocimene (12.7%), β‐pinene (7.4%) and linalool (4.0%) were the major terpenoid constituents in Z. neesanum rhizome oil. Copyright © 2007 John Wiley & Sons, Ltd.