bluuebunny/crossref_metadata_2025_split huggingface dataset:
Innocent and Less‐Innocent Solvent Ligands: A Systematic Investigation of Cationic Iron Chloride/Alcohol Complexes by Electrospray Ionization Mass Spectrometry Complemented by DFT Calculations
Authors: Trage Claudia , Diefenbach Martin , Schröder Detlef , Schwarz Helmut 
Published: January 2006

AbstractThe influence of anionic and neutral ligands on the reactivity of cationic iron complexes towards methanol, ethanol, and iso‐ and n‐propanol has been investigated by means of electrospray ionization (ESI) mass spectrometry, and in key questions the experimental results are supported by DFT calculations. The chemical processes taking place when FeCl2+ is coordinated to a variable number of alcohol molecules were investigated by collision experiments, as well as reactivity and labeling studies. The most abundant cations formed upon ESI of FeCl3/ROH mixtures can be described as consisting of a covalently bound FeCl2+ core, which is stabilized by neutral ROH ligands, for example, FeCl2(CH3OH)n+. Indications for a hydrogen‐bonding mechanism of ligands in the second coordination sphere are given by the observation of the formally hypercoordinated ion FeCl2(CH3OH)5+ and interpretation of kinetic data for n=4. Further, deuterium labeling experiments disclose a number of hidden hydrogen transfers and imply that complexes with n=1 and 2 can exist in two tautomeric forms. Upon change of the alcohol ligand from methanol to ethanol and propanol, additional reaction pathways become accessible, among which metal‐assisted dehydration of the respective alcohols by means of an ion/dipole mechanism is the most important.
[1,3]‐Transfer of Chirality during the Nicholas Reaction in γ‐Benzyloxy Propargylic Alcohols
Authors: Díaz David D. , Ramírez Miguel A. , Martín Víctor S. 
Published: January 2006

AbstractA highly regio‐ and stereoselective intramolecular [1,5]‐hydrogen‐transfer process is described. Treatment of γ‐benzyl‐protected Co2(CO)6‐α,γ‐acetylenic diols with BF3⋅OEt2 provides bis‐homopropargylic alcohols. The reaction occurs within seconds, tolerates a wide range of functionalities, and provides good yields. When the ether group is located at a stereochemically defined carbon atom, the rearrangement occurs with high stereoselectivity, transferring the chirality of the carbinol center to the newly created stereocenter. The cleavage of the benzyloxy group is totally regioselective when additional benzyl ethers are present. The scope and limitations of this novel process in densely substituted substrates are evaluated, and possible competitive reactions and/or stereochemical influences are also described. A mechanism based on a highly ordered chair‐like transition state substantiated by a theoretical study is also included.
An Efficient Method for the Preparation of Monoalkylated Sulfonamides from Unsubstituted Sulfonamides and Alkyl Diphenylphosphinites by Oxidation—Reduction Condensation Using Trimethylsilylmethyl Azide.
Authors: Aoki Hidenori , Kuroda Kiichi , Mukaiyama Teruaki 
Published: January 2006

AbstractFor Abstract see ChemInform Abstract in Full Text.
Synthesis of Highly Substituted Furans by the Electrophile‐Induced Coupling of 2‐(1‐Alkynyl)‐2‐alken‐1‐ones and Nucleophiles.
Authors: Yao Tuanli , Zhang Xiaoxia , Larock Richard C. 
Published: January 2006

AbstractFor Abstract see ChemInform Abstract in Full Text.
Synthesis and Tuberculostatic Activity of Some 1,1‐Bis‐methylthio‐2‐nitro‐ethene Derivatives.
Authors: Foks Henryk , Pancechowska‐Ksepko Danuta , Janowiec Mieczyslaw , Zwolska Zofia , Augustynowicz‐Kopec Ewa 
Published: January 2006

AbstractFor Abstract see ChemInform Abstract in Full Text.
Synthesis of Pyrrolo[2,1‐b]thiazol‐3‐one Derivatives.
Authors: Tverdokhlebov Anton V. , Andrushko Alexander P. , Tolmachev Andrey A. , Kostyuk Alexander N. , Chernega Alexander N. , Rusanov Eduard B. 
Published: January 2006

AbstractFor Abstract see ChemInform Abstract in Full Text.
9,12‐Dibenzothiazolylhypericin and 10,11‐Dibenzothiazolyl‐10,11‐didemethylhypericin: Photochemical Properties of Hypericin Derivatives Depending on the Substitution Site.
Authors: Waser Mario , Popova Yulita , Klampfl Christian W. , Falk Heinz 
Published: January 2006

AbstractFor Abstract see ChemInform Abstract in Full Text.
Synthesis and Antimycobacterial Activity of Alkyl 1‐Heteroaryl‐1H‐1,2,3‐triazole‐4‐carboxylates.
Authors: Japelj Bostjan , Recnik Simon , Cebasek Petra , Stanovnik Branko , Svete Jurij 
Published: January 2006

AbstractFor Abstract see ChemInform Abstract in Full Text.
One‐Pot Synthesis of 3‐Aryl‐3H,4H‐[1,2]‐dithiolo[3,4‐b]benzothiopyran‐4‐ones and 1‐(o‐Bromophenyl)‐3‐aryl‐2‐prop‐2‐en‐1‐ones.
Authors: Mukherjee Chandrani , Zhang Hongming , Biehl Edward R. 
Published: January 2006

AbstractFor Abstract see ChemInform Abstract in Full Text.
A Facile Synthesis of New 2‐Carboxamido‐3‐carboxythiophene and 4,5,6,7‐Tetrahydro‐2‐carboxamido‐3‐carboxythieno[2,3‐c]pyridine Derivatives as Potential Endothelin Receptors Ligands.
Authors: Pittala Valeria , Modica Maria , Romeo Giuseppe , Materia Luisa , Salerno Loredana , Siracusa Mariangela , Cagnotto Alfredo , Mereghetti Ilario , Russo Filippo 
Published: January 2006

AbstractFor Abstract see ChemInform Abstract in Full Text.
Synthesis of Some New 3‐Alkylthio Derivatives of 1‐Phenyl‐1H‐[1,3,4]thiadiazino[5,6‐b]quinoxalines
Authors: Bakavoli M. , Nikpour M. , Rahimizadeh M. 
Published: January 2006

AbstractFor Abstract see ChemInform Abstract in Full Text.
Synthesis and Properties of New Macrocyclic Compounds. Utilization of Bond Character of Hypervalent Sulfur in Tetraazathiapentalene Derivatives.
Authors: Matsumura Noboru , Hirase Ryuji , Kamitani Shigeki , Okumura Yasuyuki , Mizuno Kazuhiko 
Published: January 2006

AbstractFor Abstract see ChemInform Abstract in Full Text.
Synthesis, Antimicrobial Activity, and 77Se NMR of Some New Pyrrole Derivatives Containing a Diphenyl Selenide Moiety.
Authors: Abdel‐Hafez Sh. H. , Anthonsen H. W. , Sliwka H.‐R. , Partali V. 
Published: January 2006

AbstractFor Abstract see ChemInform Abstract in Full Text.
The First Synthesis and Reaction of β‐Ethoxy‐α‐fluoro‐α‐(phenylselanyl)ethene: Scandium or Lanthanum Triflate Catalyzed α‐Fluoroformylalkenylation of Aldehydes.
Authors: Hatanaka Fuminori , Tsuchiya Miyuki , Yoshimatsu Mitsuhiro 
Published: January 2006

AbstractFor Abstract see ChemInform Abstract in Full Text.
Bicyclic Nucleoside Inhibitors of Varicella—Zoster Virus: The Effect of Branching in the p‐Alkylphenyl Side Chain.
Authors: Luoni Giovanna , McGuigan Christopher , Andrei Graciela , Snoeck Robert , De Clercq Erik , Balzarini Jan 
Published: January 2006

AbstractFor Abstract see ChemInform Abstract in Full Text.
Fluorinated Bis(phenoxy—imine) Ti Complexes with MAO: Remarkable Catalysts for Living Ethylene and Syndioselective Living Propylene Polymerization
Authors: Furuyama Rieko , Saito Junji , Ishii Seiichi , Makio Haruyuki , Mitani Makoto , Tanaka Hidetsugu , Fujita Terunori 
Published: January 2006

AbstractFor Abstract see ChemInform Abstract in Full Text.
New Chemical Tools for Protein Modification
Authors: Francis Matthew B. , Antos John M. , Bains Sukhmine , Crochet Amanda P. , Gilmore Joshua M. , Hooker Jacob M. , Joshi Neel S. , McFarland Jesse M. , Nguyen Trung , Patel Amish A. , et al. et al. 
Published: January 2006

AbstractFor Abstract see ChemInform Abstract in Full Text.
α‐Amino Acids, β‐Amino Alcohols and Related Compounds as Chiral Auxiliaries, Ligands and Catalysts in the Asymmetric Aldol Reaction
Authors: Vicario Jose L. , Badia Dolores , Carrillo Luisa , Reyes Efraim , Etxebarria Juan 
Published: January 2006

AbstractFor Abstract see ChemInform Abstract in Full Text.
Electon‐Precise/Deficient La5‐xCaxGe4 (3.4 ≤ x ≤ 3.8) and Ce5‐xCaxGe4 (3.0 ≤ x ≤ 3.3): Probing Low‐Valence Electron Concentrations in Metal‐Rich Gd5Si4‐Type Germanides.
Authors: Wu Li‐Ming , Kim Sang‐Hwan , Seo Dong‐Kyun 
Published: January 2006

AbstractFor Abstract see ChemInform Abstract in Full Text.
Chiral (Iminophosphoranyl)ferrocenes: A New Class of Practical Ligands for Rhodium‐Catalyzed Asymmetric Hydrogenation.
Authors: Co Thanh Thien , Shim Sang Chul , Cho Chan Sik , Kim Tae‐Jeong , Kang Sang Ook , Han Won‐Sik , Ko Jaejung , Kim Chung‐Kyun 
Published: January 2006

AbstractFor Abstract see ChemInform Abstract in Full Text.
Lewis Acid—Lewis Acid Heterobimetallic Cooperative Catalysis: Mechanistic Studies and Application in Enantioselective Aza‐Michael Reaction.
Authors: Yamagiwa Noriyuki , Qin Hongbo , Matsunaga Shigeki , Shibasaki Masakatsu 
Published: January 2006

AbstractFor Abstract see ChemInform Abstract in Full Text.
Synthesis of 4‐(1,2,2‐Tricyanovinyl)‐2,6‐di‐tert‐butylphenol and the Corresponding Phenoxyl Radical.
Authors: Gorbunov A. I. , Davydova O. A. , Shpakov A. V. , Klimov. E. S. Klimov. E. S. 
Published: January 2006

AbstractFor Abstract see ChemInform Abstract in Full Text.
Alkene Synthesis: Elimination of Arenesulfinic Acid from Alkyl Aryl Sulfones Using Potassium Trimethylsilanolate as Base.
Authors: Baker‐Glenn Charles A. G. , Barrett Anthony G. M. , Gray Andrew A. , Procopiou Panayiotis A. , Ruston Mark 
Published: January 2006

AbstractFor Abstract see ChemInform Abstract in Full Text.
Unexpected Isolation of 4‐Isothiocyanatomethylene‐4H‐pyridine‐1‐carboxylic Acid Ethyl Ester as Potential Template in Organic Synthesis.
Authors: Sarhan Aladdin E. , Joergensen Per T. , Pedersen Erik B. 
Published: January 2006

AbstractFor Abstract see ChemInform Abstract in Full Text.
A New Route to Acridines: Pauson—Khand Reaction on Quinoline‐Bearing 1‐En‐7‐ynes Leading to Novel Tetrahydrocyclopenta[c]acridine‐2,5‐diones.
Authors: Patin Amaury , Belmont Philippe 
Published: January 2006

AbstractFor Abstract see ChemInform Abstract in Full Text.
The Catalytic Mannich Reaction of 1,1‐Difluoro‐2‐trialkyl(aryl)silyl‐2‐trimethylsilyloxyethenes: Preparation of β‐Amino Acid Derivatives.
Authors: Chung Woo Jin , Omote Masaaki , Welch John T. 
Published: January 2006

AbstractFor Abstract see ChemInform Abstract in Full Text.
Chemistry of Phosphorus Ylides. Part 21. New Route for the Synthesis of Azetidinones. Reaction of Phosphonium Ylides with Benzil‐, o‐Naphthoquinone‐, and Triketonemonoanils.
Authors: Soliman Fouad M. , Said Medhat M. , Maigali Soher S. 
Published: January 2006

AbstractFor Abstract see ChemInform Abstract in Full Text.
Synthesis of 5‐Hydroxy‐1,3‐benzoxathiol‐2‐one and 2‐Amino‐1,3‐benzothiazol‐6‐ol Derivatives from Chrysenequinonecarboxylic Acid.
Authors: Tret'yakova E. V. , Flekhter O. B. , Galin F. Z. , Shul'ts E. E. , Tolstikov G. A. 
Published: January 2006

AbstractFor Abstract see ChemInform Abstract in Full Text.
Dynamic Kinetic Resolution of α,β‐Unsaturated Lactones Through Asymmetric Copper‐Catalyzed Conjugate Reduction: Application to the Total Synthesis of Eupomatilone‐3.
Authors: Rainka Matthew P. , Milne Jacqueline E. , Buchwald Stephen L. 
Published: January 2006

AbstractFor Abstract see ChemInform Abstract in Full Text.
Synthesis to Determine the Absolute Configuration of (‐)‐Pyricuol, a Phytotoxin Isolated from Rice Blast Disease Fungus Magnaporthe grisea.
Authors: Nakamura Yoko , Kiyota Hiromasa , Ueda Rumi , Kuwahara Shigefumi 
Published: January 2006

AbstractFor Abstract see ChemInform Abstract in Full Text.
Parallel Synthesis and Biological Evaluation of 5,6,7,8‐Tetrahydrobenzothieno[2,3‐d]pyrimidin‐4(3H)‐one Cytotoxic Agents Selective for p21‐Deficient Cells.
Authors: Jennings Lee D. , Kincaid Scott L. , Wang Yanong D. , Krishnamurthy Girija , Beyer Carl F. , McGinnis John P. , Miranda Miriam , Discafani Carolyn M. , Rabindran Sridhar K. 
Published: January 2006

AbstractFor Abstract see ChemInform Abstract in Full Text.
Nanotube Spintronics: Magnetic Systems Based on Carbon Nanotubes
Authors: Schneider Claus M. , Kozhuharova R. , Groudeva‐Zotova S. , Zhao B. , Muehl T. , Moench I. , Vinzelberg H. , Ritschel M. , Leonhardt A. , Fink J. 
Published: January 2006

AbstractFor Abstract see ChemInform Abstract in Full Text.
Value of postoperative stereotactic radiosurgery and conventional radiotherapy for incompletely resected typical neurocytomas
Authors: Rades Dirk , Schild Steven E. 
Published: January 2006

AbstractBACKGROUNDTwo groups of central neurocytomas have been identified: typical and atypical neurocytomas. The more benign typical neurocytomas have a better prognosis. Complete resection of typical neurocytomas results in significantly better outcome than incomplete resection. The current study investigated whether the outcome after incomplete resection can be improved by postoperative stereotactic radiosurgery (SRS) or by conventional radiotherapy.METHODSThe data of all neurocytoma patients reported since 1997, when the first neurocytoma patient treated with SRS was described, were reviewed. Patients who underwent complete resection or those with atypical neurocytoma were excluded from the analysis. Three different therapies were compared for overall survival (OS) and local control (LC): incomplete resection alone (ITR), ITR followed by conventional radiotherapy (ITR+cRT), and ITR followed by stereotactic radiosurgery (ITR+SRS).RESULTSData were complete in 121 patients (59 ITR, 41 ITR+cRT, and 21 ITR+SRS). The 5‐year‐LC after ITR was 51%. LC was significantly better after ITR+cRT (87%, P = 0.001) and after ITR+SRS (100%, P = 0.004). The difference between ITR+cRT and ITR+SRS was not significant (P = 0.45). The 5‐year‐OS was 93% after ITR, 100% after ITR+cRT, and 100% after ITR+SRS. The differences between the various groups were not significant. The P‐values were 0.13 for ITR versus ITR+cRT, 0.29 for ITR versus ITR+SRS, and 1.0 for ITR+cRT versus ITR+SRS.CONCLUSIONSAfter ITR of typical neurocytomas, LC is significantly improved by both conventional radiotherapy and SRS. The results of both radiation treatments were similar. SRS is a reasonable alternative to conventional radiotherapy in selected patients. Cancer 2006. © 2006 American Cancer Society.
Problems with the current diagnostic approach to complex atypical endometrial hyperplasia
Authors: Soslow Robert A. 
Published: January 2006

Endometrial carcinoma is the most common form of genital malignancy diagnosed in women. Simple hyperplasia without atypia lies closest to normal proliferative endometrium. On the other end of the spectrum of preinvasive neoplasms is complex atypical hyperplasia (CAH), which from biologic, morphologic, and clinical perspectives resembles well differentiated endometrioid adenocarcinoma (WDA). Because CAH and WDA share so many important characteristics, tests for any one or a combination of these cannot definitively separate the two entities. Morphologically, CAH resembles WDA and, in many cases, substantial diagnostic sophistication is required to distinguish between them using current criteria. Two noteworthy articles based on the findings of the Gynecologic Oncology Group Protocol 167 have been published in this edition of Cancer and provide a glimpse of one group's approach to the diagnosis of CAH and its relevance.See also pages 804–11 and 812–9.
Fatigue in long‐term breast carcinoma survivors
Authors: Bower Julienne E. , Ganz Patricia A. , Desmond Katherine A. , Bernaards Coen , Rowland Julia H. , Meyerowitz Beth E. , Belin Thomas R. 
Published: January 2006

AbstractBACKGROUNDA longitudinal study was designed to evaluate the prevalence, persistence, and predictors of posttreatment fatigue in breast carcinoma survivors.METHODSA sample of 763 breast carcinoma survivors completed questionnaires at 1–5 and 5–10 years after diagnosis, including the RAND 36‐item Health Survey, Center for Epidemiological Studies – Depression scale (CES‐D), Breast Cancer Prevention Trial Symptom Checklist, and demographic and treatment‐related measures.RESULTSApproximately 34% of study participants reported significant fatigue at 5–10 years after diagnosis, which is consistent with prevalence estimates obtained at 1–5 years after diagnosis. Approximately 21% reported fatigue at both assessment points, indicating a more persistent symptom profile. Longitudinal predictors of fatigue included depression, cardiovascular problems, and type of treatment received. Women treated with either radiation or chemotherapy alone showed a small improvement in fatigue compared with those treated with both radiation and chemotherapy.CONCLUSIONSFatigue continues to be a problem for breast carcinoma survivors many years after cancer diagnosis, with 21% reporting persistent problems with fatigue. Several factors that may contribute to long‐term fatigue are amenable to intervention, including depression and comorbid medical conditions. Cancer 2006. © 2006 American Cancer Society.
Nonstationary electroosmotic flow in open cylindrical capillaries
Authors: Mishchuk Nataliya A. , González‐Caballero Fernando 
Published: January 2006

AbstractA theoretical model of the EOF established in a wide capillary after the application of a stepwise voltage has been developed. Both periodical and aperiodical flow regimes were studied with arbitrary pulse/pulse or pulse/pause durations and amplitudes. The numerical analysis performed for a few types of periodical regimes showed the peculiarities of the profiles of liquid velocity and its displacement both for the transition to the stationary regime and for the quasi‐stationary periodical and aperiodical regimes.
Surface treatment and characterization: Perspectives to electrophoresis and lab‐on‐chips
Authors: Pallandre Antoine , de Lambert Bertrand , Attia Rafaële , Jonas Alain M. , Viovy Jean‐Louis 
Published: January 2006

AbstractThe control and modification of surface state is a major challenge in bioanalytical sciences, and in particular in electrokinetic separation methods, due to the importance of electroosmosis. This topic has gained recently a renewed interest, associated with the development of “lab‐on‐chips” systems that extend the range of materials in which separation channels are fabricated. The surface science community has developed through the years a large toolbox of characterization tools and surface modification protocols, which is not yet fully exploited in the bioanalytical world. In this paper, we try and present an overview of these tools, in order to stimulate new ideas for improved and more controlled surface treatment strategies for separations in capillaries and microchannels. We briefly describe some physical and chemical aspects of electroosmosis (global and spatially resolved), streaming current, and streaming potential. We also review the main strategies for surface coating, and compare the advantages of physisorption, well‐organized thin self‐assembled monolayers, or conversely thick polymer “brushes”. Examples of existing applications to electrophoresis in microchannel are also given.
Timing rearrangements of SEC and SASE slave clock chains due to non‐small input phase and frequency hits in synchronisation networks
Authors: Bregni Stefano 
Published: January 2006

AbstractIn the standard architecture of synchronisation network, chains of slave clocks (namely, stand‐alone synchronisation equipment, SASE, and SDH equipment clock, SEC) transfer timing along synchronisation trails. Hence, the need to assess precisely the performance of timing transfer along such chains, not only in stationary conditions, but also under transient rearrangements occurring after input phase and frequency hits, due for example to reference switching. If possible, system analysis should be carried out beyond the usual assumption of linear behaviour, which is rather restrictive holding only for small perturbations on the input.In literature, very few papers analysed chains of slave clocks. In this work, the non‐linear transient behaviour of SEC and SASE clock chains has been simulated in the time domain, in order to evaluate their timing rearrangements after non‐small phase and frequency hits on the reference signal. Both homogeneous and non‐homogeneous chains of SEC and SASE clocks have been studied in various configurations, assuming the classic analogue PLL scheme, in order to provide a useful and comprehensive survey, both in qualitative and quantitative terms, on the timing performance achievable when planning synchronisation trails of various type and length in a synchronisation network. Copyright © 2006 AEIT
Efficient method to generate single‐copy transgenic mice by site‐specific integration in embryonic stem cells
Authors: Beard Caroline , Hochedlinger Konrad , Plath Kathrin , Wutz Anton , Jaenisch Rudolf 
Published: January 2006

AbstractTransgenic and gene‐targeted mutant mice provide powerful tools for analysis of the cellular processes involved in early development and in the pathogenesis of many diseases. Here we describe a transgene integration strategy mediated by site‐specific recombination that allows establishment of multiple embryonic stem (ES) cell lines carrying tetracycline‐inducible genes targeted to a specific locus to assure predictable temporal and spatial expression in ES cells and mice. Using homologous recombination we inserted an frt homing site into which tetracycline‐inducible transgenes can be integrated efficiently in the presence of FLPe recombinase. This strategy and the vectors described here are generally applicable to any locus in ES cells and should allow for the rapid production of mice with transgenes efficiently targeted to a defined site. genesis 44:23–28, 2006. © 2006 Wiley‐Liss, Inc.
Utilization of mental health care services among older adults with depression
Authors: Crabb Rebecca , Hunsley John 
Published: January 2006

AbstractDespite the availability of effective treatments for late life depression, data indicate that only a small minority of adults over the age of 65 years with depression access any kind of care for emotional or mental health problems. Using data from the Canadian Community Health Survey (Cycle 1.1), we compared patterns of mental health service utilization among middle‐aged (45–64 years), younger old (65–74 years), and older old (75 years and older) adults with and without depression and identified predictors associated with accessing different services (n = 59,302). Compared to middle‐aged adults with depression, individuals aged 65 and older with depression were less likely to report any mental health consultation in the past year and especially unlikely to report consulting with professionals other than a family physician. Age remained a significant predictor of mental health service utilization even after accounting for other relevant variables such as gender, marital status, years of education, depression caseness, and number of chronic medical conditions. Although the prevalence of depression is lower in older age groups, the present study provides compelling evidence that mental health services are particularly underutilized by depressed older adults. © 2005 Wiley Periodicals, Inc. J Clin Psychol 62: 299–312, 2006.