bluuebunny/crossref_metadata_2025_split huggingface dataset:
Nurse Navigators – Champions of the National Rural and Remote Nursing Generalist Framework: A solution
Authors: Byrne Amy‐Louise , Brown Janie , Willis Eileen , Baldwin Adele , Harvey Clare 
Published: March 2024

AbstractIntroductionNurse Navigators were introduced in Queensland, Australia, in 2016. Nurse Navigators coordinate person‐centred care, create partnerships, improve care coordination and outcomes and facilitate system improvement, independently of hospital or community models. They navigate across all aspects of hospital and social services, liaising, negotiating and connecting care as needed. People stay with Nurse Navigators for as long as required, though the intent is to transition them from high‐care needs to self‐management. Nurse Navigators are a working model in rural and remote areas of Queensland.ObjectiveTo describe where the rural and remote Nurse Navigator position fits within the Rural Remote Nursing Generalist Framework and to define the depth and breadth of the rural and remote Nurse Navigator's scope of practice.DesignUsing template analysis, data from focus groups and interviews were analysed against the domains of the recently released National Rural and Remote Nursing Generalist Framework. Navigators working in rural and remote areas across Queensland Health were invited to an interview (n = 4) or focus group (n = 9), conducted between October 2019 and August 2020.FindingsRural and remote Nurse Navigators are proficient in all domains of the framework and actively champion for their patients, carers and the communities where they live and work.DiscussionThis research demonstrates that rural and remote Nurse Navigators are a working model of advanced nursing practice, acting as ‘champions’ of The Framework.ConclusionThe Nurse Navigator model of care introduced to Queensland exemplifies proficient registered nurse practice to the full extent of their knowledge and skill.
The effect of enterprise unions on employment adjustment speed in Japanese firms
Authors: Noda Tomohiko , Hirano Daisuke 
Published: March 2024

AbstractUsing 20‐year dynamic panel data, we analysed the difference in employment adjustment speed and behaviour between unionized and non‐unionized firms, whether continuous or discontinuous, to investigate the effects of enterprise unions on job security in Japan. We confirmed that unionized firms were more reluctant to downsize and continue to offer stronger job security than non‐unionized firms. However, the unions’ influence on job security has gradually weakened. The primary contribution of this study is its clarification that unions in Japan played the role of guardians of job security under increasing globalization and technological innovation over the 20‐year sample period. Our clarification provides evidence that a different type of union, distinct from those in Western countries aiming for wage increases, is deeply embedded in the Japanese stakeholder system.
The influence of socio‐economic status on child temperament and psychological symptom profiles
Authors: Hong Ryan Y. , Ding Xiao Pan , Chan Kelly M. Y. , Yeung Wei‐Jun Jean 
Published: March 2024

AbstractThe influence of socio‐economic status (SES) on child temperament and psychological symptoms was examined using a nationally representative sample in Singapore. Data were available for 2169 children from 1987 families. Caregivers' reports were obtained on children aged 4–6. SES was operationalized as an aggregation of household income per capita, parental education level and housing type. Compared to their counterparts from higher SES families, children from low‐SES families tended to exhibit (a) higher negative affectivity but lower effortful control, and (b) higher internalizing and externalizing symptoms. In addition, children with a ‘resilient’ temperamental profile (i.e. low negative affectivity and high effortful control) were more likely to come from families with much higher SES, relative to children with other profiles. Children with high internalizing symptoms tended to come from low‐SES backgrounds, regardless of their externalizing symptoms. Among children with low internalizing symptoms, those with high externalizing symptoms came from lower SES backgrounds compared to those with low externalizing symptoms. Parental warmth and distress mediated the association between SES and child temperament and symptom profiles, with the exception of distress in the SES–temperament link. These findings supported the family stress model and highlighted the novel perspective of SES's influence on configurations of child temperament and symptom characteristics.
Modelling diagenetic reactions and secondary porosity generation in sandstones controlled by the advection of low‐molecular‐weight organic acids
Authors: Li Huan , Black Jay R. , Hao Yiwei , Hao Peng , Mishra Achyut , Haese Ralf R. 
Published: March 2024

AbstractHigher secondary porosity was observed in the centre of a sandstone unit in the Eocene Shahejie Formation fan delta front sandstones from the Bozhong Depression, Bohai Bay Basin. This differs from past studies showing secondary porosity mainly in the marginal parts of sandstones adjacent to shales. This study utilized reactive transport models involving low‐molecular‐weight organic acids (LMWOA) to discuss potential processes resulting in the contrary distribution of secondary porosity. An interface model simulating LMWOA diffusion from adjacent shales to the sandstone resulted in secondary porosity in sandstones adjacent to shales. In contrast, an advection model simulating advective transport of LMWOA parallel to the sandstone bedding successfully generated higher secondary porosity in the central part. The central part of the sandstone exhibited better grain sorting (greater depositional porosity) and significantly less early carbonate cements compared to the marginal sandstone parts. Consequently, the central part had greater porosity prior to the dissolution through LMWOA. The initially higher porosity in the central part allowed for a higher advective flux of LMWOA‐rich water and associated lower pH, resulting in decreased oligoclase saturation, higher oligoclase dissolution rates and ultimately higher secondary porosity. This study indicates that grain sorting during sediment deposition, early carbonate cementation, LMWOA production in adjacent shales, and advection processes collectively control the diagenetic reactions and the distribution of secondary porosity in sandstones.
The effect of one‐time abutment placement on clinical and radiographic outcomes: A 5‐year randomized clinical trial
Authors: Sanz‐Sánchez Ignacio , Molina Ana , Martin Conchita , Bollain Juan , Calatrava Javier , Sanz Mariano 
Published: March 2024

AbstractObjectiveThe aim of this study was to evaluate the long‐term (5 years) clinical efficacy of the one‐abutment one‐time protocol (test) versus the standard of care by placing the definitive abutment on the day of the prosthetic delivery (control).Materials and MethodsIn this study, 39 subjects with 60 implants were randomly allocated to either the test or the control group. Changes in the radiographic interproximal bone levels (DIB), modified sulcus bleeding index, probing depth, modified plaque index, papilla fill (Jemt score), incidence of peri‐implantitis and peri‐implant mucositis as well as patient‐reported outcomes measures (PROMs) were collected and compared at 1, 3 and 5 years.ResultsAt 5 years, the control group showed a greater, although not statistically significant, change in mean DIB values (0.97 mm vs. 0.53 mm). Regarding the other clinical parameters evaluated, no statistically significant differences were observed between groups at any time point. At 5 years, 51% of the implants presented peri‐implant mucositis (25.5% in the control and 23.5% in the test), and only one implant in the test group developed peri‐implantitis.ConclusionsThe connection and disconnection of healing abutments during the healing period was not associated with higher long‐term bone loss. Clinical outcomes and PROMs were similar between groups.
Robust fine‐grained visual recognition with images based on internet of things
Authors: Cai Zhenhuang , Yan Shuai , Huang Dan 
Published: March 2024

AbstractLabeling fine‐grained objects manually is extremely challenging, as it is not only label‐intensive but also requires professional knowledge. Accordingly, robust learning methods for fine‐grained recognition with web images collected from Internet of Things have drawn significant attention. However, training deep fine‐grained models directly using untrusted web images is confronted by two primary obstacles: (1) label noise in web images and (2) domain variance between the online sources and test datasets. To this end, in this study, we mainly focus on addressing these two pivotal problems associated with untrusted web images. To be specific, we introduce an end‐to‐end network that collaboratively addresses these concerns in the process of separating trusted data from untrusted web images. To validate the efficacy of our proposed model, untrusted web images are first collected by utilizing the text category labels found within fine‐grained datasets. Subsequently, we employ the designed deep model to eliminate label noise and ameliorate domain mismatch. And the chosen trusted web data are utilized for model training. Comprehensive experiments and ablation studies validate that our method consistently surpasses other state‐of‐the‐art approaches for fine‐grained recognition tasks in real‐world scenarios, demonstrating a significant improvement margin (2.51% on CUB200‐2011 and 2.92% on Stanford Dogs). The source code and models can be accessed at:https://github.com/Codeczh/FGVC‐IoT.
Parental communicative input as a protective factor in Bangladeshi families living in poverty: A multi‐dimensional perspective
Authors: Wei Ran , Sullivan Eileen F. , Begum Fatema , Rahman Navin , Tofail Fahmida , Haque Rashidul , Nelson Charles A. 
Published: March 2024

AbstractStudies from high‐income populations have shown that stimulating, supportive communicative input from parents promote children's cognitive and language development. However, fewer studies have identified specific features of input supporting the healthy development of children growing up in low‐ or middle‐income countries. The current study proposes and tests a multi‐dimensional framework for understanding whether and how caregiver communicative input mediates the associations between socio‐economic conditions and early development. We also examine how caregiver conceptual scaffolding and autonomy support uniquely and synergistically explain variation in child outcomes. Participants were 71 Bangladeshi families with five‐year‐olds who were exposed to a range of biological and psychosocial hazards from birth. Caregiver‐child interactions during snack sharing and semi‐structured play were coded for caregiver conceptual scaffolding, autonomy support, and child engagement. Findings indicate that the two dimensions of input were correlated, suggesting that caregivers who provided richer conceptual scaffolds were simultaneously more supportive of children's autonomy. Notably, conceptual scaffolding and autonomy support each mediated associations between maternal education and child verbal intelligence quotient (IQ) scores. Further, caregivers who supported greater autonomy in their children had children who participated in conversations more actively, and these children in turn had higher performance IQ scores. When considered simultaneously, conceptual scaffolding was associated with verbal IQ over and above autonomy support, whereas autonomy support related to child engagement, controlling for conceptual scaffolding. These findings shed new light on how environmental factors may support early development, contributing to the design of family‐centered, culturally authentic interventions. A video abstract of this article can be viewed at https://youtu.be/9v_8sIv7akoResearch Highlights
Studies from high‐income countries have identified factors mitigating the impacts of socio‐economic risks on development. Such research is scarce in low‐ and middle‐income countries.
The present study conceptualized and evaluated caregiver communicative input in Bangladeshi families along two interrelated yet distinct dimensions: conceptual scaffolding and autonomy support.
Conceptual scaffolding and autonomy support individually mediated associations between maternal education and child verbal IQ, shedding light on protective factors in families living in poverty.
Parents providing richer conceptual scaffolds were simultaneously more supportive of children's autonomy. However, the two dimensions each related to cognition and language through unique pathways.
Racial disparities in the utilization of invasive neuromodulation devices for the treatment of drug‐resistant focal epilepsy
Authors: Alcala‐Zermeno Juan Luis , Fureman Brandy , Grzeskowiak Caitlin L. , Potnis Ojas , Taveras Maria , Logan Margaret W. , Rybacki Delanie , Friedman Daniel , Lowenstein Daniel , Kuzniecky Ruben , French Jacqueline ,   the HEP2 investigators
Published: March 2024

AbstractRacial disparities affect multiple dimensions of epilepsy care including epilepsy surgery. This study aims to further explore these disparities by determining the utilization of invasive neuromodulation devices according to race and ethnicity in a multicenter study of patients living with focal drug‐resistant epilepsy (DRE). We performed a post hoc analysis of the Human Epilepsy Project 2 (HEP2) data. HEP2 is a prospective study of patients living with focal DRE involving 10 sites distributed across the United States. There were no statistical differences in the racial distribution of the study population compared to the US population using census data except for patients reporting more than one race. Of 154 patients enrolled in HEP2, 55 (36%) underwent invasive neuromodulation for DRE management at some point in the course of their epilepsy. Of those, 36 (71%) were patients who identified as White. Patients were significantly less likely to have a device if they identified solely as Black/African American than if they did not (odds ratio = .21, 95% confidence interval = .05–.96, p = .03). Invasive neuromodulation for management of DRE is underutilized in the Black/African American population, indicating a new facet of racial disparities in epilepsy care.
The experience of growing up with a sibling who has depression from emerging adults' perspectives
Authors: Shinan‐Altman Shiri , Levkovich Inbar 
Published: March 2024

AbstractObjectiveThe aim was to explore the experiences of growing up with a sibling with depression from the perspective of emerging adult siblings.BackgroundGrowing up with a sibling who experiences depression profoundly impacts the personal lives of emerging adults. This study addresses a research gap by delving into the unique experiences of these emerging adult siblings.MethodsUtilizing a qualitative‐phenomenological approach, we examined the experiences of 25 emerging adults (aged 18–29) who had lived with a depressed sibling during adolescence. In‐depth, semistructured interviews were conducted. Data collection continued until concept saturation. Thematic analysis was employed.ResultsWe identified two central themes in the participants' experiences. In the first theme, significant challenges were illuminated within the parent–child relationship, marked by frustration, the assumption of parental roles, emotional disconnect, and hindrances to personal growth. The second theme pertained to the implications of their sibling's depression on the emerging adults' personal lives, resulting in sacrifices, emotional turmoil, and a sense of responsibility. Participants also exhibited resilience, empathy, and personal growth.ConclusionsThis research illuminates the nuanced dynamics among emerging adults with depressed siblings, underscoring the need for tailored interventions that support both caregiving responsibilities and personal development. Incorporating sibling perspectives into clinical practice can enhance intervention strategies and promote well‐being.ImplicationsThese findings underscore the need for personalized support that enables emerging adults to balance caregiving for their depressed siblings with their own personal growth, with a focus on fostering family communication and resilience.
Investigation of bioactive properties, phenolic compounds and fatty acid profiles of wheat breads enriched with poppy seed paste
Authors: Al‐Juhaimi Fahad , Mohamed Ahmed Isam A. , Özcan Mehmet Musa , Karrar Emad 
Published: March 2024

SummaryTotal phenol and flavonoid amounts of breads with poppy paste at different concentrations were established between 41.94 (control) and 56.71 mg GAE per 100 g (poppy paste 20%) to 72.14 (control) and 379.29 mg per 100 g (poppy paste 30%), respectively. Antioxidant capacity values of breads varied between 0.08 (control) and 1.04 mmol kg−1 (poppy paste 30%). L* results of breads were determined between 64.86 and 75.07, while a* and b* results vary between 0.51 and 5.47; 20.97 and 25.96, respectively. Gallic acid and 3,4‐dihydroxybenzoic acid contents of breads were determined between 13.00 (poppy paste 30%) and 63.21 mg per 100 g (poppy paste 20%) to 23.71 (poppy paste 10%) and 36.57 mg per 100 g (poppy paste 20%), respectively. Oleic and linoleic acid values of the bread oils were determined between 34.44% (control) and 40.06% (poppy paste 30%) to 34.945 (control) and 46.69% (poppy paste 10%), respectively. As a result, the most popular bread samples were enriched with 20% poppy paste, followed by 30%, control and 10% poppy paste added bread samples in decreasing order.
Extrinsic and intrinsic drivers of natural killer cell clonality
Authors: Rückert Timo , Romagnani Chiara 
Published: March 2024

SummaryClonal expansion of antigen‐specific lymphocytes is the fundamental mechanism enabling potent adaptive immune responses and the generation of immune memory. Accompanied by pronounced epigenetic remodeling, the massive proliferation of individual cells generates a critical mass of effectors for the control of acute infections, as well as a pool of memory cells protecting against future pathogen encounters. Classically associated with the adaptive immune system, recent work has demonstrated that innate immune memory to human cytomegalovirus (CMV) infection is stably maintained as large clonal expansions of natural killer (NK) cells, raising questions on the mechanisms for clonal selection and expansion in the absence of re‐arranged antigen receptors. Here, we discuss clonal NK cell memory in the context of the mechanisms underlying clonal competition of adaptive lymphocytes and propose alternative selection mechanisms that might decide on the clonal success of their innate counterparts. We propose that the integration of external cues with cell‐intrinsic sources of heterogeneity, such as variegated receptor expression, transcriptional states, and somatic variants, compose a bottleneck for clonal selection, contributing to the large size of memory NK cell clones.
RETRACTED: Effects of evidence‐based nursing on surgical site wound infection in patients undergoing acute appendicitis surgery: A meta‐analysis
Authors: Liu Feng , Zhou Juan , Wu Xue‐Lian 
Published: March 2024

AbstractThis study aimed to comprehensively evaluate the effects of evidence‐based nursing (EBN) intervention on wound infection and postoperative complications in patients after appendectomy for acute appendicitis (AA), with the expectation of providing a theoretical basis for postoperative care in AA. Randomised controlled trials (RCTs) on the postoperative application of EBN in patients with AA were searched in PubMed, Web of Science, Cochrane Library, Embase, China Biomedical Literature Database, Wanfang and China National Knowledge Infrastructure from the inception of databases to October 2023. Two authors screened and evaluated the literature based on the inclusion and exclusion criteria, and data were extracted from the final included literature. Stata software (version 17.0) was employed for data analysis. In total, 29 RCTs involving 2848 patients with AA were included, with 1424 in the EBN group and 1424 in the conventional care group. The analyses revealed that patients with AA who experienced EBN were significantly less likely to develop postoperative wound infections (odds ratio [OR] = 0.23, 95% confidence intervals [CIs]: 0.14–0.38, p < 0.001) and postoperative complications (OR = 0.20, 95% CI: 0.15–0.26, p < 0.001) as opposed to conventional care. Available evidence suggests that EBN can effectively reduce the risk of wound infection and postoperative complications in patients undergoing appendectomy for AA, thereby improving patient prognosis. This finding is worth promoting in the clinical practice.
MRPS16 promotes lung adenocarcinoma growth via the PI3K/AKT/Frataxin signalling axis
Authors: Cheng Zaixing , Xue Kaming , Xiong Cui , Zheng Zhikun , Li Jinsong , Qiao Xinwei 
Published: March 2024

AbstractAlthough MRPS16 is involved in cancer development, its mechanisms in developing LAUD remain unclear. Herein, qRT‐PCR, WB and IHC were utilized for evaluating MRPS16 expression levels, while functional assays besides animal experiments were performed to measure MRPS16 effect on LAUD progression. Using WB, the MRPS16 effect on PI3K/AKT/Frataxin signalling pathway was tested. According to our study, MRPS16 was upregulated in LAUD and was correlated to the advanced TNM stage as well as poor clinical outcomes, which represent an independent prognostic factor. Based on functional assays, MRPS16 is involved in promoting LAUD growth, migration and invasion, which was validated further in subsequent analyses through PI3K/AKT/Frataxin pathway activation. Moreover, MRPS16‐knockdown‐mediated Frataxin overexpression was shown to restore the reduction in tumour cells proliferation, migration and invasion. Our results revealed that MRPS16 caused an aggressive phenotype to LAUD and was a poor prognosticator; thus, targeting MRPS16 may be effectual in LAUD treatment.
Research progress on the regulatory mechanism of integrin‐mediated mechanical stress in cells involved in bone metabolism
Authors: Yang Li , Chen Hong , Yang Chanchan , Hu Zhengqi , Jiang Zhiliang , Meng Shengzi , Liu Rong , Huang Lan , Yang Kun 
Published: March 2024

AbstractMechanical stress is an internal force between various parts of an object that resists external factors and effects that cause an object to deform, and mechanical stress is essential for various tissues that are constantly subjected to mechanical loads to function normally. Integrins are a class of transmembrane heterodimeric glycoprotein receptors that are important target proteins for the action of mechanical stress stimuli on cells and can convert extracellular physical and mechanical signals into intracellular bioelectrical signals, thereby regulating osteogenesis and osteolysis. Integrins play a bidirectional regulatory role in bone metabolism. In this paper, relevant literature published in recent years is reviewed and summarized. The characteristics of integrins and mechanical stress are introduced, as well as the mechanisms underlying responses of integrin to mechanical stress stimulation. The paper focuses on integrin‐mediated mechanical stress in different cells involved in bone metabolism and its associated signalling mechanisms. The purpose of this review is to provide a theoretical basis for the application of integrin‐mediated mechanical stress to the field of bone tissue repair and regeneration.