bluuebunny/crossref_metadata_2025_split huggingface dataset:
Quantitative radionuclide angiocardiography
Authors: Scholz Peter M. , Rerych Stephen K. , Moran Jon F. , Newman Glenn E. , Douglas James M. , Jones Robert H. , Sabiston David C. 
Published: March 2007

AbstractThis study introduces a new method for calculating actual left ventricular volumes and cardiac output from data recorded during a single transit of a radionuclide bolus through the heart, and describes in detail current radionuclide angiocardiography methodology. A group of 64 healthy adults with a wide age range were studied to define the normal range of hemodynamic parameters determined by the technique. The normal radionuclide cardiac index averaged 3.25 ± 0.75 liters/min/m2, the end‐diastolic volume index was 62 ± 16 ml/m2, the stroke volume index was 40 ± 9 ml/m2, and the ejection fraction was 0.66 ± 0.07. Radionuclide angiocardiograms were performed in patients undergoing cardiac catheterization to validate the measurements. In 33 patients studied by both techniques on the same day, a close correlation was documented for measurement of ejection fraction (r = 0.89) and end‐diastolic volume (r = 0.89). Determination of the linear regression equation for the end‐diastolic volumes obtained by the two methods (EDVcath = 1.26 × EDVRN − 7.56) permitted correction of end‐diastolic volume and provided an approach for calculation of stroke volume and cardiac output. To validate the method of volumetric cardiac output calculation, 33 simultaneous radionuclide and indocyanine green dye determinations of cardiac output were performed in 18 normal young adults and correlated closely over a range of 4–17 liters/min (r = 0.94). These independent comparisons of radionuclide measurements with two separate methods document that initial transit radionuclide angiocardiography accurately assesses left ventricular function.
Transvenous biopsy of mediastinal lymphoma invading the superior vena cava
Authors: Meltzer Richard S. , Stebbins Robert , Hunt Sharon A. , Billingham Margaret E. 
Published: March 2007

AbstractMalignant disease in the mediastinum often presents as superior vena cava syndrome. In this emergency setting, expeditious tissue diagnosis is frequently of extreme importance. We report a case where tissue diagnosis was obtained by cardiac biopsy technique.
Demonstration of abnormal proximal conduction system by his bundle electrocardiography in a patient with a single ventricle
Authors: Sohi Gurbachan S. , Flowers Nancy C. 
Published: March 2007

AbstractHis bundle electrocardiography in a patient with a single ventricle and 2:1 block showed the block to be proximal to the His bundle. The sinus node recovery time was normal. In addition, there was suggestive evidence of a functionally and/or structurally abnormal accessory pathway. The role of His bundle electrocardiography in a patient with a single ventricle in defining the function of various portions of the conduction system was thus demonstrated.
Safe transthoracic left ventricular puncture performed with echocardiographic guidance
Authors: Vignola Paul A. , Swaye Paul S. , Gosselin Arthur J. 
Published: March 2007

AbstractRetrograde aortic left ventricular pressure recording is difficult to obtain and often unreliable in the presence of a mechanical aortic valve prosthesis. Under echocardiographic guidance, we have safely performed transthoracic left ventricular puncture for pressure recording in seven patients with an aortic valve prosthesis. The transducer is placed at the left sternal border and then slid laterally until the right ventricular cavity and interventricular septal echoes disappear, but before the echoes from the left lung are recorded. The chest wall is marked and the transducer is angled until the mitral valve echoes are identified. The transducer angle and direction are recorded with external markers, and the left ventricular cavity depth is measured. An 18‐gauge needle is then inserted the determined depth into the left ventricle, guided exactly by the echocardiographic external markers. The procedure was successful in each patient on the first attempt without a single complication.We conclude that this technique affords the operator greater control when left ventricular pressure must be recorded by transthoracic puncture and that it may reduce the risk of potentially serious complications.
A new technique in advancing the catheter from the left atrium to the left ventricle
Authors: Wennevold A. 
Published: March 2007

AbstractA technique is described by which a catheter is advanced from the left atrium to the left ventricle during a right heart catheterization via the leg.A loop in the catheter is created by the clockwise twisting of the catheter while it is gently pushed against the posterior left wall of the left atrium. The catheter is then pulled back and is twisted counter‐clockwise. The catheter has to be soft, and biplane fluroscopy is required.During a 16‐month period 162 consecutive infants and children had heart catheterization performed, during which a pediatric NIH catheter was passed to the left atrium. The loop‐technique was attempted in 95 patients and was successful in 66 patients. One or two attempts were usually sufficient. No complications were encountered apart from two brief episodes of bradycardia.The technique is easy to perform with a reasonable success rate. It seems most useful in infants in whom 5F catheters are used.
Transfemoral snaring of broken catheters from the right heart in small infants
Authors: Chung Kyung J. , Chernoff Harvey L. , Leape Lucian L. , Kreidberg Marshall B. 
Published: March 2007

AbstractSuccessful retrieval of embolized central venous catheter fragments from the right heart was accomplished in two small infants weighing 2100 and 4050 Gm respectively. The catheters had been broken off at the site of entry into the vein and migrated to right atrium. A 5F end‐hole Cook catheter with 0.018 inch diameter, 125cm long Curry snaring wire with flexible mid‐segment was successfully utilized through the femoral vein percutaneously to remove the foreign body without complication.
New preshaped catheter for investigation of aortic stenosis by femoral approach: A study of 100 cases
Authors: Crochet D. , de Laguerenne J. , Petitier H. 
Published: March 2007

AbstractThe authors describe their technique of catheterization of the left ventricle in aortic stenosis by a femoral approach based on a newly designed double‐curved catheter. The method has been used successfully in 87 of 100 consecutive cases. The advantages and drawbacks of the method are discussed.
The diagnostic accuracy of combined clinical and noninvasive cardiac evaluation: Comparison with findings at cardiac catheterization
Authors: Alpert Joseph S. , Sloss Laurence J. , Cohn Peter F. , Grossman William 
Published: March 2007

AbstractThe accuracy of combined clinical and noninvasive cardiac diagnostic evaluation was prospectively examined in 108 consecutive patients referred to the heart station for echocardiographic examination prior to cardiac catheterization. History, physical examination, scalar electrocardiography, chest roentgenography, phonocardiography and pulse recording, and M‐mode echocardiography were employed by the heart station cardiologist, who assigned one or more diagnoses to each patient. In addition, one of three management strategies was proposed for each patient: 1) surgery without cardiac catheterization; 2) medical therapy without cardiac catheterization; or 3) cardiac catheterization for clarification of the diagnosis. The results of the combined clinical and noninvasive evaluation were independently reviewed for each patient and compared with the diagnosis determined by cardiac catheterization, results of cardiac surgery, and total hospital course. Diagnostic predictions employing combined clinical and noninvasive cardiac evaluation were completely correct in 86% of patients, and management strategy was correct in 97% of individuals. In approximately one‐half of all patients full cardiac catheterization or coronary arteriography was recommended. All management strategy errors and two‐thirds of diagnostic errors occurred in patients with mitral regurgitation, aortic regurgitation, or coronary artery disease.Combined clinical and noninvasive evaluation results in accurate diagnostic information adequate for the formulation of appropriate management strategies in the majority of patients, but many individuals with cardiac disease still require invasive evaluation for complete diagnosis.
Limitations of post‐extrasystolic potentiation in assessing regional myocardial viability in man
Authors: Slack John D. , Landon John K. , Cole James S. , Hanley Henry G. , O'Connor William 
Published: March 2007

AbstractTo investigate the usefulness of regional response to post‐extrasystolic potentiation as a predictor of left ventricular viability in patients with coronary artery disease, 46 patients underwent calibrated biplane left ventricular cineangiography during which a single, timed ventricular premature contraction was introduced.Results: Of 758 normal or hypokinetic segments, 486 (64.1%) showed a positive response to post‐extrasystolic potentiation. Of 116 akinetic or dyskinetic segments, only 51 (43.9%) showed a positive response to post‐extrasystolic potentiation (P <0.001). Because akinetic or dyskinetic areas would not be expected to respond to post‐extrasystolic potentiation based on animal laboratory data, alternative explanations were sought to explain such positive response in man. Analysis of percent change in chord length of normal or hypokinetic segments adjacent to akinetic or dyskinetic segments that did or did not respond to post‐extrasystolic potentiation revealed (10.2% ± 1.2%) vs (1.3% ± 0.7%) improvement, respectively (P <0.001) (mean ± SE).Conclusion: Passive rather than active events may be responsible for “improved” regional wall motion following post‐extrasystolic potentiation in akinetic or dyskinetic regions. If unrecognized, these factors may lead to improper interpretation of “intervention ventriculography” utilizing post‐extrasystolic potentiation.
Refractory variant angina controlled with combined drug therapy in a patient with a single coronary artery
Authors: Phaneuf Denis C. , Waters David D. , Dauwe Franz , Théroux Pierre , Pelletier Guy , Mizgala Henry F. 
Published: March 2007

AbstractA young man with a single left coronary artery and refractory variant angina is described. Spontaneous coronary artery spasm developed during coronary arteriography at the site of a 50% fixed left anterior descending coronary artery stenosis. Frequent episodes of rest angina with transient ST segment elevation persisted in hospital in spite of treatment with three different calcium antagonist drugs. Symptoms disappeared only when the combination of nifedipine, diltiazem, isosorbide dinitrate, and nitroglycerin ointment were given. Ergonovine testing was used to objectively assess the response to treatment.
The use of a microcomputer in the evaluation of echocardiograms
Authors: Menke James A. , Von Behren Patricia A. , Bashiru Mohammed , Bada Henrietta S. , Khanna Narinder N. 
Published: March 2007

AbstractA low‐cost microcomputer system is used to calculate cardiac parameters from echocardiographic (Echo) measurements and produce a chartable report. The system is simple, uses Basic language, and provides for data storage.
Early experience of transluminal coronary angioplasty (TCA) by the brachial artery (the sones technique in transluminal angioplasty)
Authors: Angelini Paolo , Leatherman Louis , Springer Arthur , Krajcer Zvonimir , Lufschanowski Roberto , Stamatiou Eleftherios , Wagner Ephraim , Armbrust Charles , Leachman Robert 
Published: March 2007

AbstractSixteen translumlnal coronary angioplasty procedures (TCA), eight right coronary artery (RCA) and eight left anterior descending coronary artery (LAD), by the brachial artery cut‐down approach, were attempted with 9/16 (56%) immediate successes and 2/16 (12%) early recurrences. The procedure success rate for RCA obstructive lesions, 6/8 (75%) was greater than for LCA obstructions, 3/8 (38%). In six unsuccessful procedures the balloon catheter could not be advanced into the lesion, and in one unsuccessful procedure dissection of the coronary artery proximal to the lesion occurred. The brachial (Sones) technique for transluminal coronary angioplasty permits the use of softer guiding catheters for selective probing and approach to the coronary lesion but may be more likely to induce coronary spasm. Complete and high‐resolution pre TCA anglograms with multiple views to disclose the exact anatomy of the coronary artery and Its lesion Is essential to ensure successful dilatation.
Biochemical measurements of endomyocardial biopsies
Authors: Unverferth Donald V. , Fertel Richard H. , Altschuld Ruth , Magorien Raymond D. , Lewis Richard P. , Leier Carl V. 
Published: March 2007

AbstractThe purpose of this study is to investigate the validity of performing biochemical analyses on human endomyocardlal biopsies. One problem of such analyses is the decay of metabolites between the time of biopsy and the analyses. This was addressed by varying the time delay from biopsy to submersion in liquid nitrogen (‐200°C). Neither cyclic AMP or cyclic GMP changed significantly up to 90 seconds after biopsy. The reproduclblllty of the assays in human heart biopsies was determined by submitting paired samples from each procedure. The ATP content was determined by a fluorescent technique and was related to the protein and creative content. The average ATP of 25 paired samples was 12.3 nm per mg protein; the average difference between the paired samples was ‐0.6, and the 95%confidence Interval was 5.6 nm/mg protein. The average ATP‐to‐creatJne ratio was 0.25; the 95% confidence interval was 0.12. The cyclic AMP and cyclic GMP were found to average 3.3 and 0.25 femtomoles/mcg protein, respectively. The 95% confidence intervals were 1.8 and 0.12 fmoles/mcg protein. The problems of sampling error and blood and connective tissue contamination decrease the reliability of the biochemical analyses. Reproduclblllty is adequate, however, to acquire meaningful biochemical information on the human heart.
Aortic cusp involvement causing severe aortic regurgitation in a case of relapsing polychondritis
Authors: Sohi Gurbachan S. , Desai Amarjit M. , Ward Will W. , Flowers Nancy C. 
Published: March 2007

AbstractA case with relapsing polychondritis is described where primary involvement of the aortic valve cusps produced severe aortic regurgitation requiring valve replacement. An aneurysmal dilatation of the ascending aorta developing later led to disruption of the prosthesis requiring re‐operation. Superior vena caval obstruction, an abdominal aortic aneurysm which ruptured and required resection, and obstructive lesions in common iliac arteries, presumably the result of the same process that involved the aorta and the cartilaginous structures, were also seen.
Sudden occlusion of a saphenous vein bypass graft relieved by direct injection of nitroglycerine
Authors: Baduini Giovanni , Marra Sebastiano , Angelino Pier Federico 
Published: March 2007

AbstractAn unusual case of sudden occlusion of a saphenous vein bypass graft to the right coronary artery, during a coronary angtographlc study, is presented. Such occlusion was relieved by direct intragraft nitroglycerine injection, as typically happens in case of coronary arterial spasm. A possible pathogenetlc mechanism, based on the present knowledge of platelet aggregation and the role of the powerful vasoactive agent Throm‐boxane A2, is discussed.
Percutaneous entry of the brachial artery for left heart catheterization using a sheath
Authors: Fergusson David J. G. , Kamada Roy O. 
Published: March 2007

AbstractPercutaneous entry of the brachial artery using a sheath system has been attempted in 223 patients undergoing left heart Catheterization; successfully, In 212. After arterial puncture, a dilator and sheath are passed over a short guWewire. A number 7–80 cm Sones specially stiffened coronary catheter Is passed through the sheath, and left heart Catheterization Is performed in the usual manner. The study can usually be completed with this single catheter. Initial entry, as well as any needed catheter change, Is facilitated by the use of an inflatable sphygmomanometer cuff around the upper arm. Ease of manipulation and patient comfort have been satisfactory, and brachial artery spasm has not been encountered. There have been no major complications and a low incidence (∼ 1.5%) of brachial arterial occlusion.
Effect of informed consent and educational background on patient knowledge, anxiety, and subjective responses to cardiac catheterization
Authors: Freeman William R. , Pichard Augusto D. , Smith Harry 
Published: March 2007

AbstractThirty‐four patients undergoing elective cardiac catheterization were followed linearly with three questionnaires during their hospitalization to study some of the effects of informed consent. Patients learn about catheterization from the informed consent session conducted by a cardiology fellow. Several areas of knowledge deficiency were found. The emotional experience of hospitalization and the amount of knowledge about catheterization determined at the end of hospital stay is shown to be dependent on the educational level of the patient. Several recommendations are made for the conduct of the informed consent sessions to improve the knowledge of the less educated.
Assessment of left ventricular function in patients with isolated severe disease of the left anterior descending artery: Clinical, electrocardiographic, hemodynamic, and angiographic correlations
Authors: Iskandrian Abdulmassih S. , Weber Jan R. , Mundth Eldred D. , Downey Kathleen B. , Segal Bernard L. , Kimbiris Demetrios , Mintz Gary S. , Bemis Charles E. 
Published: March 2007

AbstractThe purpose of this study was to define the spectrum of left ventriculographic (LV) abnormalities in 60 patients with isolated ≥90% diameter narrowing of the left anterior descending artery (LAD). The patients were divided into three groups: Group I (26 patients) had normal left ventricular (LV) function with ejection fraction (EF) of >60% and no akinetic‐dyskinetic segment representing abnormal contracting segments (ACS) of the left ventricular wall; Group II (15 patients) had mild to moderate LV dysfunction with EF of 40–60% and an akinetic‐dyskinetic segment of < 30% of the end diastolic perimeter (0–30%; mean, 11.6%) and Group III (19 patients) had severe LV dysfunction with EF <40%, or an akinetic‐dyskinetic segment of ≥30 % (30–81%; mean, 41.5%) or both.The data obtained from the history, physical examination, electrocardiogram (ECG), chest x‐ray studies, hemodynamic studies, left ventriculography, and coronary arteriography were entered and filed on a memory disc in an IBM 370‐168 computer.Analysis of the results showed: (1) more severe LV dysfunction is associated with increased incidence of large hearts, gallops, decreased cardiac output, and occlusion of the LAD. (2) ECG evidence of infarction is also associated with higher incidence of the abnormalities of the indices of LV dysfunction. (3) LAD occlusion (versus stenosis) has a higher incidence of severe LV dysfunction and prior infarction. (4) The site of LAD disease did not predict the extent of left ventricular dysfunction. (5) Collaterals did not protect against severe LV dysfunction.
Peak left ventricular pressure/volume (Emax) during exercise in control subjects and children with left‐sided cardiac disease
Authors: Alpert Bruce S. , Benson Lee , Olley Peter M. 
Published: March 2007

AbstractThe peak ratio of left ventricular systolic pressure/systolic volume (PV) has been shown to be a close approximation to Emax, an index of contractility independent of both preload and afterload. We studied 17 children with left‐sided cardiac disease during catheterization by a combined high‐fidelity catheter and m‐mode echocardiographic technique. Emax, indexed for body surface area, was calculated at rest and during supine exercise at 25% and 50% of maximal upright workload. In addition, we studied 15 control subjects with a noninvasive approximation of peak P/V, the peak systolic LV pressure/smallest systolic LV volume. Patients with left ventricular pressure overload showed an increased Emax, value at rest and a further increase with exercise. Patients with left ventricular volume overload or cardiomyopathy had a normal value of Emax, at rest and had only small increases with exercise. Patients with both volume and pressure overload had a resting Emax, value that was increased, but no further increase occurred with exercise. Emax, in children seems to be a sensitive index of contractility during physiologic stress and can be used to assess left ventricular functional reserve capacity both pre‐ and post‐operatively.
Echocardiographic diagnosis of right ventricular hypertrophy: Correlation with ECG and necropsy findings in 248 patients
Authors: Prakash Ravi 
Published: March 2007

AbstractMeasurements of right ventricular wall thickness (RVWT) by echocardiography and at necropsy correlated well (r = 0.83) in 36 patients. Echocardiography had a sensitivity of 93% and a specificity of 95% in diagnosing right ventricular hypertrophy (RVH) at necropsy; electrocardiography (ECG) had a sensitivity of 31% and a specificity of 85% in diagnosing RVH.An additional 212 patients were studied by echocardiography and ECG. Based on echocardiographic criteria of RVH (RVWT ≥5 mm), 134 of 212 patients had RVH, and 78 were without RVH: the ECG had a sensitivity of 27% and a specificity of 88% for diagnosing RVH when correlated with the echocardiographic criteria. The mean dia‐stolic RVWT was 6.0 ± 1.4 mm in 134 RVH patients and 3.4 ± 0.8 mm in 78 no‐RVH patients (P < 0.05). Diagnosis of RVH was difficult by ECG in 73 patients due to conduction defects or old myocardial infarction; the RVWT measurements were useful in evaluating RVH in these patients.We conclude that echocardiographic measurements of RVWT are useful in the diagnosis of RVH and are more sensitive than the ECG criteria in adults.
Acquired coronary‐to‐bronchial artery communication: A possible cause of coronary steal
Authors: Green Curtis E. , Kelley Michael J. , Higgins Charles B. , Bookstein Joseph J. 
Published: March 2007

AbstractAn unusual case of an acquired coronary‐to‐bronchial artery communication is presented. Collateral flow to the lung was provided by the right coronary circulation following obstruction of pulmonary blood flow by chronic pulmonary emboli. A coronary steal phenomenon may have caused an exacerbation of cardiac symptoms by further reducing already compromised coronary blood flow in a patient with atherosclerotic coronary artery disease.
Diastolic segmental coronary artery obliteration in constrictive pericarditis
Authors: Goldberg Emanuel , Stein Julius , Berger Marvin , Berdoff Russell L. 
Published: March 2007

AbstractA patient with severe constrictive pericarditis demonstrated a new angiographic sign of segmental diastolic obliteration of an obtuse marginal branch of the circumflex system of the left coronary artery.
Influence of recording scale on determination of left ventricular end‐diastolic pressure
Authors: Hieb Barry R. , Krone Ronald J. , Lagler Regis G. , Oliver G. Charles 
Published: March 2007

AbstractLeft ventricular (LV) pressure waveforms for 20 beats, originally recorded at 200 scale (200 torr/10 cm) were rescaled by a computer system to represent the identical beats recorded at 40 scale (40 torr/10 cm). Both the original and the rescaled beats were independently evaluated by eight cardiologists who were unaware of the nature of the manipulated data. For each beat the average left ventricular end‐diastolic pressure (LVEDP) identified by the eight cardiologists was higher when analyzed on the 200 scale, with an average difference of 2.8 torr (P < 0.001). This scale‐dependence of pressure analysis has implications for the development of automated pressure analysis algorithms and for physician review of computer‐determined LVEDP data points.