bluuebunny/crossref_metadata_2025_split huggingface dataset:
Impact of mental health comorbidity in children and young adults with inflammatory bowel disease: a UK population-based cohort study
Authors: Cooney Rachel , Barrett Kevin , Russell Richard K 
Published: February 2024

ObjectiveTo evaluate the impact of mental health comorbidity in children and young adults with inflammatory bowel disease (IBD).DesignRetrospective observational study.SettingRepresentative population, routinely collected primary care data from the UK Optimum Patient Care Research Database (2015–2019).ParticipantsPatients with IBD aged 5–25 years with mental health conditions were compared with patients with IBD of the same age without mental health conditions.Primary and secondary outcome measuresOutcomes comprised quality-of-life indicators (low mood, self-harm, parasuicide, bowel symptoms, absence from school or work, unemployment, substance use and sleep disturbance), IBD interventions (medication, abdominal surgery, stoma formation and nutritional supplements) and healthcare utilisation (primary care interactions and hospital admissions).ResultsOf 1943 individuals aged 5–25 years with IBD, 295 (15%) had a mental health comorbidity. Mental health comorbidity was associated with increased bowel symptoms (adjusted incident rate ratio (aIRR) 1.82; 95% CI 1.33 to 2.52), sleep disturbance (adjusted HR (aHR) 1.63; 95% CI 1.02 to 2.62), substance use (aHR 3.63; 95% CI 1.69 to 7.78), primary care interactions (aIRR 1.33; 95% CI 1.12 to 1.58) and hospital admissions (aIRR 1.87; 95%CI 1.29 to 2.75). In individuals ≥18 years old, mental health comorbidity was associated with increased time off work (aHR 1.55; 95% CI 1.21 to 1.99).ConclusionsMental health comorbidity in children and young adults with IBD is associated with poorer quality of life, higher healthcare utilisation and more time off work. It is imperative that affected young patients with IBD are monitored and receive early mental health support as part of their multidisciplinary care.Trial registration numberThe study protocol was specified and registered a priori (ClinicalTrials.gov study identifier:NCT05206734).
Carbon footprint of hospital laundry: a life-cycle assessment
Authors: John Joseph , Collins Michael , O'Flynn Kieran , Briggs Tim , Gray William , McGrath John 
Published: February 2024

ObjectivesTo assess greenhouse gas (GHG) emissions from a regional hospital laundry unit, and model ways in which these can be reduced.DesignA cradle to grave process-based attributional life-cycle assessment.SettingA large hospital laundry unit supplying hospitals in Southwest England.PopulationAll laundry processed through the unit in 2020–21 and 2021–22 financial years.Primary outcome measureThe mean carbon footprint of processing one laundry item, expressed as in terms of the global warming potential over 100 years, as carbon dioxide equivalents (CO2e).ResultsAverage annual laundry unit GHG emissions were 2947 t CO2e. Average GHG emissions were 0.225 kg CO2e per item-use and 0.5080 kg CO2e/kg of laundry. Natural gas use contributed 75.7% of on-site GHG emissions. Boiler electrification using national grid electricity for 2020–2022 would have increased GHG emissions by 9.1%, however by 2030 this would reduce annual emissions by 31.9% based on the national grid decarbonisation trend. Per-item transport-related GHG emissions reduce substantially when heavy goods vehicles are filled at ≥50% payload capacity. Single-use laundry item alternatives cause significantly higher per-use GHG emissions, even if reusable laundry were transported long distances and incinerated at the end of its lifetime.ConclusionsThe laundry unit has a large carbon footprint, however the per-item GHG emissions are modest and significantly lower than using single-use alternatives. Future electrification of boilers and optimal delivery vehicle loading can reduce the GHG emissions per laundry item.
Sickle Eye Project: a cross-sectional, non-interventional study of the prevalence of visual impairment due to sickle cell retinopathy and maculopathy in the UK
Authors: Dinah Christiana , Balaskas Konstantinos , Greystoke Brigit , Awadzi Rossby , Beke Peter , Ahern Roger , Talks James 
Published: February 2024

IntroductionSickle cell disease (SCD) is one of the most common genetic disorders in the UK, with over 15 000 people affected. Proliferative sickle cell retinopathy (SCR) is a well-described complication of SCD and can result in significant sight loss, although the prevalence in the UK is not currently known. There are currently no national screening guidelines for SCR, with wide variations in the management of the condition across the UK.Methods and analysisThe Sickle Eye Project is an epidemiological, cross-sectional, non-interventional study to determine the prevalence of visual impairment due to SCR and/or maculopathy in the UK. Haematologists in at least 16 geographically dispersed hospitals in the UK linked to participating eye clinics will offer study participation to consecutive patients meeting the inclusion criteria attending the sickle cell clinic. The following study procedures will be performed: (a) best corrected visual acuity with habitual correction and pinhole, (b) dilated slit lamp biomicroscopy and funduscopy, (c) optical coherence tomography (OCT), (d) OCT angiography where available, (e) ultrawide fundus photography, (f) National Eye Institute Visual Function Questionnaire-25 and (g) acceptability of retinal screening questionnaire. The primary outcome is the proportion of people with SCD with visual impairment defined as logarithm of the minimum angle of resolution ≥0.3 in at least one eye. Secondary outcomes include the prevalence of each stage of SCR and presence of maculopathy by age and genotype; correlation of stage of SCR and maculopathy to severity of SCD; the impact of SCR and presence of maculopathy on vision-related quality of life; and the acceptability to patients of routine retinal imaging for SCR and maculopathy.Ethics and disseminationEthical approval was obtained from the South Central–Oxford A Research Ethics Committee (REC 23/SC/0363). Findings will be reported through academic journals in ophthalmology and haematology.
Impact of involvement in mental health professional education on patient educators: a qualitative systematic review
Authors: Stanyon Miriam , Ryan Karl , Dilks Joanna , Hartshorn Kirsty , Ingley Paul , Kumar Brijesh , Sira Mahalinggappa Sridevi , Mullins Elizabeth , Misquitta Olivia , Sidwell Alexa , Dave Subodh 
Published: February 2024

Objectives
Patient involvement in mental health professional education is required by policy but lacks a robust evidence base. The impact of involvement in education on patients with mental health conditions may differ from that of patients with other conditions. This study aims to review the impact of involvement in mental health professional education on the patients with mental health conditions involved.

Setting
Electronic databases MEDLINE, PubMed, AMED, EMBASE, PsycINFO, Emcare, BNI, HMIC and CINAHL were systematically searched to find articles reporting on health professional teaching interventions involving patients with mental health conditions and the psychological, social or physical impact of involvement. The search took place in August 2023.

Results
Findings from 20 articles were amalgamated into four synthesised findings: (1) Impact of general involvement (2) impact of making a difference through teaching, (3) impact of new relationships and (4) impact of talking about experiences.

Conclusions
Patient involvement in mental health professional education can be beneficial for patients with mental health conditions when their experiences are respected and valued as expertise by students and academic staff. The experiences of patient educators in the mental health field are unique in that teaching activities interact with their mental health. Future research should evaluate patient involvement in the mental health field separately and report research findings according to reporting guidelines.

PROSPERO registration number
CRD42020224907.
Ammonium phosphate is a potential nitrogen supplement in nitrogen-limiting diets for growing pigs
Authors: Buchinski Miranda J. , Camire Carley M. , Babatunde Olufemi O. , Shoveller Anna K. , Columbus Daniel A. 
Published: February 2024

Reduced protein diets may be limiting in dietary nitrogen (N). The objective of this study was to determine the impact of non-protein nitrogen (NPN) inclusion and lysine content on growth performance of growing pigs. Pen-housed growing pigs were randomly assigned to one of six dietary treatments to test the impact of NPN inclusion and dietary lysine content for 28 days. NPN inclusion increased feed efficiency and lean depth ( P < 0.05). Final body weight increased with greater lysine ( P < 0.05) but was not impacted by NPN ( P > 0.05). Ammonium phosphate may be an appropriate N source in N-limiting diets for pigs.
Repeating fast radio bursts produced by a strange star interacting with its planet in an eccentric orbit
Authors: Nurmamat Nurimangul , Huang Yong-Feng , Geng Jin-Jun , Kurban Abdusattar , Li Bing 
Published: February 2024

AbstractFRB 180916 is an important repeating fast radio burst (FRB) source. Interestingly, the activity of FRB 180916 shows a well-regulated behavior, with a period of 16.35 days. The bursts are found to occur in a duty cycle of about 5 days in each period. In this study, we suggest that the bursts of FRB 180916 are produced by a strange star interacting with its planet. The planet moves in a highly eccentric orbit around its compact host, with the periastron only slightly beyond the tidal disruption radius. As a result, the planet will be partially disrupted every time it passes through the periastron. The stripped material from the planet will be accreted by the strange star, falling to the polar cap region along the magnetic field lines and accumulated there. It will finally lead to a local collapse when the crust at the polar region is overloaded, triggering an FRB. The observed 16.35 day period corresponds to the orbital motion of the planet, and the 5 day duty cycle is explained as the duration of the partial disruption near the periastron. The energy released in each local collapse event can be as high as $$\sim 10^{42}\,\textrm{erg}$$

∼

10
42

erg

, which is large enough to account for typical FRBs even if the radiation efficiency is low.
Composition and distribution of sedimentary organic matter in nearshore Berriasian strata (‘German Wealden’) of the eastern Lower Saxony Basin, NW Germany
Authors: Stoepke Fritz-Lukas , Götz Annette E. , Blumenberg Martin , Gravendyck Julia , Erbacher Jochen , Pierau Roberto , Schöner Robert , Heimhofer Ulrich 
Published: February 2024

Abstract
In the Lower Saxony Basin of Northern Germany, the Earliest Cretaceous (Berriasian, ‘German Wealden’) is represented by organic-rich shales assigned to the Isterberg Formation, which have been deposited under brackish-lacustrine conditions in a partially restricted basin. Towards the southern basin margin, these shales interfinger with nearshore sandstones sourced from the Deister-Hils delta. In order to better understand the environmental conditions and depositional dynamics of the Isterberg Fm, the sedimentary organic matter has been studied with a combined approach including bulk rock organic geochemistry and palynofacies analysis. The lower part (W 1 to W 3) is interpreted to reflect very shallow-water conditions and episodic emergence, indicated by multiple occurrences of palaeosol horizons, rhizoliths and intercalated coal beds formed within a mud-dominated and protected domain of the delta plain. The overlying sand-rich interval represents a nearshore deltaic setting. A distinct change is observed in the upper part (W 4), indicating more distal conditions characterized by clay-dominated sedimentation, abundant lumachelle interbeds and a predominance of aquatic-derived organic matter. The newly acquired data fill a gap in the record between the proximal and distal strata of the Berriasian Lower Saxony Basin and provide new insights into the accumulation and preservation of organic matter within this exceptional depositional setting.
Speaking and Writing: Essentially the Same and Importantly Different
Authors: Yaffe Philip 
Published: February 2024

Each "Communication Corner" essay is self-contained; however, they build on each other. For best results, before reading this essay and doing the exercise, go to the first essay "How an Ugly Duckling Became a Swan," then read each succeeding essay.
If you have been following these Communication Corner essays, you have read the above paragraph many, many times. However, this essay will be radically different because is not self-contained; rather it is the summation of everything that has gone before. Every effort has been made to make each section self-contained. Where this was not possible, links to previous Communication Corner essays have been included.
Arterial Health Markers in Relation to Behavior and Cognitive Outcomes at School Age
Authors: Gonçalves Romy , Gaillard Romy , Cecil Charlotte , Defina Serena , Steegers Eric. A. P. , Jaddoe Vincent W. V. 
Published: February 2024

Background
Impaired arterial health is associated with a decline in cognitive function and psychopathology in adults. We hypothesized that these associations originate in early life. We examined the associations of blood pressure, common carotid artery intima media thickness, and carotid distensibility with behavior and cognitive outcomes during adolescence.

Methods and Results
This study was embedded in the Dutch Generation R Study, a population‐based prospective cohort study from early fetal life onwards. Blood pressure, carotid intima media thickness, and carotid distensibility were measured at the age of 10 years. At the age of 13 years, total, internalizing and externalizing problems and attention‐deficit hyperactivity disorder symptoms were measured using the parent‐reported Child Behavior Checklist (CBCL/6–18), autistic traits were assessed by the Social Responsiveness Scale, and IQ was assessed using the Wechsler Intelligence Scale for Children‐Fifth Edition. A 1‐SD score higher mean arterial pressure was associated with lower odds of internalizing problems (odds ratio [OR], 0.92 [95% CI, 0.85–0.99]). However, this association was nonsignificant after correction for multiple testing. Carotid intima media thickness and carotid distensibility were not associated with behavior and cognitive outcomes at 13 years old.

Conclusions
From our results, we cannot conclude that the associations of blood pressure, carotid intima media thickness, and carotid distensibility at age 10 years with behavior and cognitive outcomes are present in early adolescence. Further follow‐up studies are needed to identify the critical ages for arterial health in relation to behavior and cognitive outcomes at older ages.
Redescription of two known species of Taeniacanthidae (Copepoda, Cyclopoida) parasitic on Japanese filefishes (Actinopterygii)
Authors: Izawa Kunihiko 
Published: February 2024

Abstract
Cirracanthus monacanthi (Yamaguti, 1939) and Taeniacanthus balistae (Claus, 1864) are redescribed based on specimens recovered from Stephanolepis cirrhifer (Temminck & Schlegel, 1850) and Aluterus monoceros (Linnaeus, 1758) (Tetraodontiformes, Monacanthidae), respectively, in Japan. The description of the copepodid V female of T. balistae is the first time for the species.
Impact of the co-cultivation of macroalgae (Ulva lactuca f. fasciata) on the composition of biofloc in a zero water exchange system used for rearing Pacific white shrimp (Litopenaeus vannamei) (Decapoda, Dendrobranchiata)
Authors: Turan Gamze , Carvalho Chagas Andrezza , Costa César S.B. , Wasielesky Jr. Wilson F.B. , da Silva Poersch Luís H. 
Published: February 2024

Abstract
In a closed, or zero water exchange, greenhouse aquaculture system, this study examined the interaction between the aggregation flocs in the mono- and co-cultivation of Pasific white shrimp, Litopenaeus vannamei (300 individuals/m3) with macroalgae, Ulva lactuca f. fasciata at different densities of Ulva (1, 2 and 3 g/l). The investigation was conducted under zero water exchange conditions. The accumulated flocs were compared between the various treatment groups: without Ulva (Treatment Control Group), Ulva at 1 g/l density (T1: Treatment 1), Ulva at 2 g/l (T2: Treatment 2), and Ulva at 3 g/l (T3: Treatment 3). Ultimately, it was determined that Ulva cultivation using the Biofloc system actually helped to ensure the water quality in the zero water exchange culture system during the 35-day experimental period with reduced cyanophyte densities, that can cause toxic algal blooms in aquaculture systems. This was interpreted to result from the fact that Ulva is a naturally occurring bioremediation agent.
The species and physiological diversity of Bifidobacterium genus in Gallus gallus domesticus are influenced by feeding model and niche adaptations
Authors: Grande S.M.M. , Argañaraz Martı́nez E. , Babot J.D. , Andrada E. , Quiroga M. , Garro M. , Saguir F. , Perez Chaia A. 
Published: February 2024

Abstract
Species diversity of the Bifidobacterium genus was scarcely explored in different rearing systems of poultry. The aim of the study was to isolate intestinal species and compare their physiological and traits for adaptation to the avian intestinal niche. Fourteen strains isolated from chickens of intensive rearing farms and free-range hens, were identified by 16S rDNA sequencing, rep-PCR fingerprinting, and carbohydrates fermentation. Strains belonged to species Bifidobacterium pseudolongum subsp. pseudolongum and subsp. globosum, B. pullorum, B. animalis subsp lactis, B. boum, B. thermacidophilum subsp. thermacidophilum and B. thermophilum. One strain of B. animalis and B. pullorum, and two of B. pseudolongum subsp. pseudolongum were obtained from chicks, while the others were from free-range adult hens. Growth (in MRSc) at the poultry physiological temperature, acids production in caecal water with raffinose (rCW), ex vivo adhesion (%) to avian intestinal epithelial cells (IEC), and auto-aggregation (%) were used for discrimination inter- and intra-specific. Significantly different acetic and lactic acids production and growth temperatures were observed in strains of the same species/subspecies. Remarkable auto-aggregation capability was observed in B. thermacidophilum subsp. thermacidophilum LET 406 (40.2 ± 1.1%), while adhesion property was highlighted in B. pseudolongum subsp. pseudolongum LET 408 (65.30 ± 4.75% in jejunum; 46.05 ± 2.80 in ileum). Scanning Electronic Microscopy of the interaction IEC-LET 408 revealed an irregular bacterial surface exhibiting vesicle-like arrangements and filaments that formed a network among bacteria cells and with the epithelial cells, as possible adaptative response to promote its persistence in the gut. These finds will be valuable for bacterial supplements design intended to intensive rearing.
Substance use and its association with mental health among Swiss medical students: A cross-sectional study
Authors: Gaume Jacques , Carrard Valérie , Berney Sylvie , Bourquin Céline , Berney Alexandre 
Published: February 2024

Background: Studies on mental health and substance use among medical students indicated worrying prevalence but have been mainly descriptive. Aim: To evaluate the prevalence of substance use in a sample of medical students and investigate whether mental health variables have an influence on substance use. Methods: The data were collected as part of the first wave of the ETMED-L, an ongoing longitudinal open cohort study surveying medical students at the University of Lausanne (Switzerland). N = 886 students were included and completed an online survey including measures of mental health (depression, suicidal ideation, anxiety, stress, and burnout) and use of and risk related with several substances (tobacco, alcohol, cannabis, cocaine, stimulants, sedatives, hallucinogens, opioids, nonmedical prescription drugs, and neuroenhancement drugs). We evaluated the prevalence of use of each substance and then tested the association between mental health and substance use in an Exploratory Structural Equation Modeling framework. Results: Statistical indices indicated a four-factor solution for mental health and a three-factor solution for substance use. A factor comprising risk level for alcohol, tobacco, and cannabis use – which were the most prevalent substances – was significantly associated with a burnout factor and a factor related to financial situation and side job stress. There was a significant association between a factor comprising depression, anxiety, and suicidal ideation and a factor related to the use of sedatives, nonmedical prescription drugs and neuroenhancement drugs. Although their use was less prevalent, a factor comprising the risk level of stimulants and cocaine use was significantly but more mildly related to the burnout factor. A factor comprising stress related to studies and work/life balance as well as emotional exhaustion was not related to substance use factors. Conclusion: In this sample of medical students, the prevalence of substance use was substantial and poorer mental health status was related with higher substance use risk levels.
‘If he thought that I was going to go and hurt myself, he had another thing coming’: Treatment experiences of those with large to massive rotator cuff tears and the perspectives of healthcare practitioners
Authors: Fahy Kathryn , Galvin Rose , Lewis Jeremy , McCreesh Karen 
Published: February 2024

Objective To explore the treatment experiences of those diagnosed with large to massive rotator cuff tears and the perspectives of healthcare practitioners providing their care. Design A qualitative descriptive study using reflexive thematic analysis. Setting In-person focus groups were undertaken in a clinical setting (private practice [ n = 1]; public outpatient [ n = 2]). Semi-structured interviews were conducted online via Microsoft Teams. Participants Patients diagnosed with these tears ( n = 12) and healthcare practitioners ( n = 11). Results Two interlinking themes were identified based on the care received and provided for patients with symptomatic large to massive rotator cuff tears: 1) Positive treatment experiences and management: Education, clear communication and reassurance around prognosis were the foundation of positive patient–clinician care. Sub-themes of pain relief, exercise prescription and confidence in their pathway underpinned this experience. This proficiency in care was affirmed by some healthcare practitioners who spoke about the importance of confidence and experience in their management plan even in times of poor progress. 2) Negative treatment experiences and management: Uncertainty, delays and exacerbation of pain flawed the patient–clinician care. Sub-themes of inappropriate pain relief, inappropriate exercise prescription and uncertainty impacted their care. Some healthcare practitioners acknowledged knowledge gaps led to uncertainty especially when choosing the next step of care and were quick to escalate care to deflect this uncertainty. Conclusions The findings suggest discordance exists between the patient's experiences and expectations when the delivery of care was by less experienced and confident healthcare practitioners in the management of this condition. This highlights the need for improved education and support for healthcare practitioners.