bluuebunny/crossref_metadata_2025_split huggingface dataset:
The dynamic responses of mood and sleep physiology to chronic sleep restriction and subsequent recovery sleep
Authors: Jones Christopher W , Larson Olivia , Basner Mathias , Dinges David F 
Published: April 2024

Abstract
Healthy sleep of sufficient duration preserves mood and disturbed sleep is a risk factor for a range of psychiatric disorders. As adults commonly experience chronic sleep restriction (SR), an enhanced understanding of the dynamic relationship between sleep and mood is needed, including whether susceptibility to SR-induced mood disturbance differs between sexes. To address these gaps, data from N = 221 healthy adults who completed one of the two multi-day laboratory studies with identical 9-day SR protocols were analyzed. Participants randomized to the SR (n = 205) condition underwent 5 nights of SR to 4 hours of time-in-bed and were then randomized to one of the seven sleep doses that ranged from 0 to 12 hours in 2 hours increments; participants randomized to the control (n = 16) condition received 10 hours time-in-bed on all study nights. The Profile of Mood States (POMS) was used to assess mood every 2 hours during wakefulness and markers of sleep homeostasis (EEG slow-wave activity (SWA)) were derived via polysomnography. Mood progressively deteriorated across SR with marked disturbances in somatic mood components. Altered sleep physiology contributed to mood disturbance whereby increased EEG SWA was associated with increased POMS Total Mood Disturbance scores, a finding specific to males. The mood was restored in a dose–response fashion where improvements were greater with longer sleep doses. These findings suggest that when lifestyle and environmental factors are inhibited in the laboratory, the affective consequences of chronic sleep loss are primarily somatic mood disturbances. Altered sleep homeostasis may contribute to mood disturbance, yet sleep-dependent mechanisms may be sex-specific.
The Phyllosphere Microbiome in Tsuga canadensis: Relationships with Resistance to the Insect Adelges tsugae and Effects of the Pesticide Dinotefuran
Authors: Burke David J. , Lumsden Caleb , Carrino-Kyker Sarah R. , Medeiros Juliana , Danielson Sharon 
Published: April 2024

Tsuga canadensis (eastern hemlock) is an important tree species in North America, but it has been subject to threats from invasive insects such as Adelges tsugae (hemlock woolly adelgid). A. tsugae is native to Asia, and Tsuga species from Asia are typically resistant to this insect. In this study, we examined the phyllosphere microbiome of two hemlock species native to North America and susceptible to A. tsugae ( T. canadensis and T. caroliniana) as well as two species native to Asia and resistant to A. tsugae ( T. chinensis and T. diversifolia). Because pesticide application is often used to treat native Tsuga species impacted by A. tsugae, we also examined the response of the microbiome and overall plant physiology to the pesticide dinotefuran in T. canadensis. We found significant differences in the bacterial and fungal microbiome among the four species of Tsuga. Dinotefuran also significantly affected bacterial communities, but not fungal communities, of T. canadensis. The genus Methylobacterium, which uses methanol produced during plant cell elongation and growth, was a significant indicator of trees not subject to dinotefuran. This suggests that dinotefuran may have reduced cell growth in treated trees. Despite changes in the microbiome, dinotefuran application did not significantly affect plant physiology; however, the coefficient of variation in dinotefuran-treated trees was larger than that in non-treated trees. Our results suggest that the microbiome could play a role in mediating insect resistance in Tsuga species and that pesticide application could affect the phyllosphere microbiome, with implications for plant growth and resistance. [Formula: see text] Copyright © 2024 The Author(s). This is an open access article distributed under the CC BY-NC-ND 4.0 International license .
Causal Effects of High Stress Assessed Via Interviews on Mental and Physical Health
Authors: Kiuchi Keita , Kang Xin , Nishimura Ryota , Sasayama Manabu , Matsumoto Kazuyuki 
Published: April 2024

Objectives
This study investigated the causal effect of high stress assessment via an interview on the mental and physical health of workers 1 month later.

Methods
Stress assessment interviews and feedback were conducted with 50 Japanese workers. In addition to the interviewer, two occupational health professionals assessed participants’ stress based on recordings. The average treatment effect was estimated by propensity score matching.

Results
High stress, according to the interview-based assessment, had a significant negative causal effect on self-reported well-being 1 month later (95% confidence interval: −3.02, −1.10). In addition, no effect of high stress on stress load, mental and physical symptoms, or burnout was observed.

Conclusions
This study provides important insights into the prognosis of individuals who were assessed through interviews to have high stress. The findings are expected to help automate stress assessments using computer agents.
Underlying Reasons for Primary Care Visits Where Chlamydia Testing Was Performed in the United States, 2019 to 2022
Authors: Tao Guoyu , Hufstetler Kaitlin , He Larry , Patel Chirag G. , Rehkopf David , Phillips Robert L. , Pearson William S. 
Published: April 2024

BackgroundIn the United States, most chlamydia cases are reported from non–sexually transmitted disease clinics, and there is limited information focusing on the reasons for chlamydia testing in private settings. These analyses describe clinical visits to primary care providers where chlamydia testing was performed to help discern between screening and diagnostic testing for chlamydia.MethodsUsing the largest primary care clinical registry in the United States, the PRIME registry, chlamydia tests were identified usingCurrent Procedural Terminologyprocedure codes and categorized as diagnostic testing for sexually transmitted infection (STI)–related symptoms, screening for chlamydia, or “other,” based onClassification of Diseases, Tenth RevisionEvaluation and Management codes selected for visits.ResultsOf 120,013 clinical visits with chlamydia testing between January 1, 2019, and December 31, 2022, 70.4% were women; 20.6% were with STI-related symptoms, 59.9% were for screening, and 19.5% for “other” reasons. Of those 120,013 clinical visits with chlamydia testing, the logit model showed that patients were significantly more likely to have STI-related symptoms if they were female than male, non-Hispanic Black than non-Hispanic White, aged 15 to 24 years than aged ≥45 years, and resided in the South than in the Northeast.ConclusionIt is important to know what proportion of chlamydial infections is identified through screening programs and to have this information stratified by demographics. The inclusion of laboratory results could further facilitate a better understanding of the impact of chlamydia screening programs on the identification and treatment of chlamydia in private office settings in the United States.
The Core Competencies for Public Health in Canada: Opportunities and Recommendations for Modernization
Authors: Shephard Rosemarie , Uy Justine , Otterman Victoria , Betker Claire , Sandhu Harman S. , Tjaden Lynda , Apatu Emma , Di Ruggiero Erica , Musto Richard , Pawa Jasmine , Steinberg Malcolm , Payne Elspeth , Fang Lily 
Published: April 2024

Context:The 2008 Public Health Agency of Canada’s (PHAC’s) “Core Competencies for Public Health in Canada” (the “Canadian core competencies”) outline the skills, attitudes, and knowledge essential for the practice of public health. The core competencies represent an important part of public health practice, workforce development, and education in Canada and internationally. However, the core competencies are considered outdated and are facing calls for review, expansion, and revision.Objective:To examine the literature on public health competencies to identify opportunities and recommendations for consideration when reviewing and updating the Canadian core competencies.Methods:This narrative literature review included 4 components: 3 literature searches conducted between 2021 and 2022 using similar search strategies, as well as an analysis of competency frameworks from comparable jurisdictions. The 3 searches were conducted in collaboration with the Health Library to identify core competency-relevant scholarly and gray literature published in English since 2007. Reference lists of sources identified were also reviewed. During the data extraction process, one researcher screened each source, extracted competency-relevant information, and categorized these data into key findings.Results:After identifying 2392 scholarly and gray literature sources, 166 competency-relevant sources were included in the review. Findings from these sources were synthesized into 3 main areas: (1) competency framework methodology and structure; (2) competencies to add; and (3) competencies to modify.Discussion:These findings demonstrate that updates to Canada’s core competencies are needed and overdue. Recommendations to support this process include establishing a formal governance structure for the competencies’ regular review, revision, and implementation, as well as ensuring that priority topics applicable across all competency categories are integrated as overarching themes. Limitations of the evidence include the potential lack of applicability and generalizability to the Canadian context, as well as biases associated with the narrative literature review methodology.
Adolescent school-based mental health screening: a best practice implementation project
Authors: Farr John , Palokas Michelle 
Published: April 2024

ABSTRACTIntroduction:More than one in ten people globally live with a mental health illness. Adolescent mental health is a major contributor to that statistic, as 27% of adolescents have one or more mental, emotional, developmental, or behavioral problems. School-based health care clinics can provide mental health services for this age group.Objectives:This project aimed to promote evidence-based practices regarding adolescent mental health screening in schools.Methods:This project used the JBI Evidence Implementation Framework to promote evidence-based practices for adolescent mental health screening in schools. The JBI framework is grounded in an audit and feedback process, along with a structured approach to identifying and managing barriers to compliance with best practices. Five audit criteria representing best practice recommendations were developed. A baseline audit was conducted, followed by the implementation of an improvement strategy. The project was finalized with a follow-up audit to determine any changes in compliance with best practice recommendations.Results:The baseline survey of students revealed a 25% average compliance for audit criteria 1 and 2. The primary barrier to compliance was students’ unawareness of the availability of mental health services. The improvement strategy included an educational presentation for students regarding mental health. The follow-up audit revealed an increase in compliance with best practices.Conclusions:The project achieved a 29% increase in compliance with best practices, although only 23% of the students were reached via the improvement strategy.Spanish abstract:http://links.lww.com/IJEBH/A189
Discovery of dynamic changes in 3D chromatin architecture through polymer physics model
Authors: Anubhooti  , Abdul Wasim , Narayan Priyanka Kriti , Mondal Jagannath , Pongubala Jagan 
Published: April 2024

AbstractThe 3D organisation of the genome provides an intricate relationship between the chromatin architecture and its effects on the functional state of the cell. Recent advances in high-throughput sequencing and chromosome conformation capture technologies elucidated a comprehensive view of chromatin interactions on a genome-wide scale but provides only a 2D representation of how the chromatin is organised inside the cell nucleus. To quantitatively understand the structural alterations and dynamics of chromatin in 3D, we have developed a computational model that not only captures the hierarchical structural organisation but also provides mechanistic insights into the dynamics of spatial rearrangements of chromatin in developing lymphoid lineage cells. From the combination of approaches of polymer physics representing chromatin as a homopolymeric chain and incorporation of the biological information of chromosomal interactions inferred from the Hi-C data, we generated a coarse grained bead-on-a-string polymer model of chromatin to comprehend the mechanisms underlying the differential chromatin architecture. Our study showed that our simulated chromatin structure recapitulates the intrinsic features of chromatin organisation, including the fractal globule nature, compartmentalization, presence of topologically associating domains (TADs), phase separation and spatial preferences of genomic regions in the chromosomal territories. Comparative analyses of these simulated chromatin structures of differentiating B cell stages revealed compartmental switching and changes in the spatial positioning of lineage specific genomic regions. Analysis of the compactness of the switched regions showed insights into their acquired open-closed states for gene regulation and hence governing the cell fate through consequent structural rearrangement. Based on the remarkable performance of our model, we emphasise on its predictive potential by identifying switching of novel regions that demonstrated undergoing structural rearrangement which was subsequently validated through their differential expression patternsin vitro. These results reveal that although the chromatin organisation seems similar in most cell types, it undergoes distinct structural changes for the regulatory role of chromatin in sustaining cell specificity.
Multiscale characterization of additively manufactured PMMA: the influence of sterilization
Authors: Rufo-Martín Celia , Mantecón Ramiro , Youssef Geroge , Miguelez Henar , Díaz-Álvarez Jose 
Published: April 2024

Purpose
Polymethyl methacrylate (PMMA) is a remarkable biocompatible material for bone cement and regeneration. It is also considered 3D printable but requires in-depth process–structure–properties studies. This study aims to elucidate the mechanistic effects of processing parameters and sterilization on PMMA-based implants.

Design/methodology/approach
The approach comprised manufacturing samples with different raster angle orientations to capitalize on the influence of the filament alignment with the loading direction. One sample set was sterilized using an autoclave, while another was kept as a reference. The samples underwent a comprehensive characterization regimen of mechanical tension, compression and flexural testing. Thermal and microscale mechanical properties were also analyzed to explore the extent of the appreciated modifications as a function of processing conditions.

Findings
Thermal and microscale mechanical properties remained almost unaltered, whereas the mesoscale mechanical behavior varied from the as-printed to the after-autoclaving specimens. Although the mechanical behavior reported a pronounced dependence on the printing orientation, sterilization had minimal effects on the properties of 3D printed PMMA structures. Nonetheless, notable changes in appearance were attributed, and heat reversed as a response to thermally driven conformational rearrangements of the molecules.

Originality/value
This research further deepens the viability of 3D printed PMMA for biomedical applications, contributing to the overall comprehension of the polymer and the thermal processes associated with its implementation in biomedical applications, including personalized implants.
Elastoplastic nanoindentation behaviors of sintered nano-silver under various sintering parameters
Authors: Dai Yanwei , Zhao Libo , Qin Fei , Chen Si 
Published: April 2024

Purpose
This study aims to characterize the mechanical properties of sintered nano-silver under various sintering processes by nano-indentation tests.

Design/methodology/approach
Through microstructure observations and characterization, the influences of sintering process on the microstructure evolutions of sintered nano-silver were presented. And, the indentation load, indentation displacement curves of sintered silver under various sintering processes were measured by using nano-indentation test. Based on the nano-indentation test, a reverse analysis of the finite element calculation was used to determine the yielding stress and hardening exponent.

Findings
The porosity decreases with the increase of the sintering temperature, while the average particle size of sintered nano-silver increases with the increase of sintering temperature and sintering time. In addition, the porosity reduced from 34.88%, 30.52%, to 25.04% if the ramp rate was decreased from 25°C/min, 15°C/min, to 5°C/min, respectively. The particle size appears more frequently within 1 µm and 2 µm under the lower ramp rate. With reverse analysis, the strain hardening exponent gradually heightened with the increase of temperature, while the yielding stress value decreased significantly with the increase of temperature. When the sintering time increased, the strain hardening exponent increased slightly.

Practical implications
The mechanical properties of sintered nano-silver under different sintering processes are clearly understood.

Originality/value
This paper could provide a novel perspective on understanding the sintering process effects on the mechanical properties of sintered nano-silver.
House building techniques for achieving sustainable development goals
Authors: Shahraki Abdol Aziz , Mollashahi Hossein 
Published: April 2024

AbstractThis study aims to design and build a pilot home according to the United Nations sustainable development goals (UN SDGs). The research methodology is a nature‐oriented housing policy to promote renewable energy consumption in homes for cleaner environments. This study analyzes the structural elements of traditional homes in the eastern south of Iran. This study examines the UN SDGs in planning and designing the model to find the advantages of nature‐oriented constructions compared to the current harmful development projects damaging nature, environments, ecosystems, and the earth. The building model presented in this paper is in harmony with the UN SDGs. The model provides an architectural and planning procedure to prevent the earth from damaging fossil consumption‐built environments in the world. Calculations show that the housing pilot model saves USD 3600 in energy consumption per household on average. The outcomes of this study prove the hypothesis that the use of renewable energy in homes is beneficial economically and environmentally. This study implicates housing policies in shifting planning and design methods toward UN SDGs. Policies are applicable globally in the housing programs.
Inadequate pregnancy‐specific knowledge among patients with inflammatory bowel disease: A multicenter survey in China
Authors: Li Rui Xia , Wu Tong , Li Xiao Fei , Zhou He , Shi Yan Ting , Wang Fang , Liang Jie 
Published: April 2024

ObjectivesThe perceptions and attitudes of inflammatory bowel disease (IBD) patients towards pregnancy may affect their fertility plan and disease progression. We performed a nationwide multicenter survey of pregnancy‐related knowledge among gastroenterologists and IBD patients in China to investigate whether specific educational interventions could improve their understanding and broadly influence fertility plan.MethodsA cross‐sectional questionnaire regarding pregnancy‐specific knowledge was carried out among 63 IBD centers in China. Questionnaires were collected from 185 physicians and 609 patients. The patients then received education regarding pregnancy during IBD and filled in the same questionnaire again. Their knowledge regarding pregnancy during IBD was compared before and after education.ResultsCompared to physicians, patients' knowledge regarding fertility (39.1% vs 70.8%), imaging examinations (22.8% vs 72.4%), endoscopy performed during pregnancy (19.9% vs 71.4%), and vaccination for infants (16.6% vs 46.5%) was significantly more limited (all P < 0.001). There was a lack of knowledge among gastroenterologists regarding the delivery mode (36.8%), medications (36.8%), and emergency surgery (26.5%) during pregnancy in patients with IBD. After education, the patients showed significant improvement in knowledge regarding medications (26.7% vs 51.7%), fertility (45.0% vs 63.3%), heritability (40.0% vs 58.3%), indications for emergency surgery (15.0% vs 53.3%), imaging examinations during pregnancy (20.0% vs 40.0%), and vaccinations for infants (26.7% vs 45.0%) (all P < 0.05).ConclusionsPregnancy‐specific IBD knowledge needs to be improved among certain gastroenterologists and patients in China. Educational interventions can partially improve the knowledge levels of the patients.
Utilization of lasso peptides for biodegradation of polycyclic aromatic hydrocarbons
Authors: Simpson Waltena , Brigmon Robin L. , Howard Daniel , Jackson Makaela , Kugler Alex , Brown Victoria 
Published: April 2024

AbstractMany microbial genes involved in degrading recalcitrant environmental contaminants such as polycyclic aromatic hydrocarbons (PAHs) have been identified and characterized. However, all molecular mechanisms required for PAH utilization have not yet been elucidated. In this work, we demonstrate the proposed involvement of lasso peptides in the utilization of the PAH phenanthrene in Sphingomonas BPH. Transpositional mutagenesis of Sphingomonas BPH with the miniTn5 transposon yielded 3 phenanthrene utilization deficient mutants, #257, #1778, and #1782. In mutant #1782, Tn5 had inserted into the large subunit of the naph/bph dioxygenase gene. In mutant #1778, Tn5 had inserted into the B2 protease gene of a lasso peptide cluster. This finding is the first report on the role of lasso peptides in PAH utilization. Our studies also demonstrate that interruption of the lasso peptide cluster resulted in a significant increase in the amount of biosurfactant produced in the presence of glucose when compared to the wild‐type strain. Collectively, these results suggest that the mechanisms Sphingomonas BPH utilizes to degrade phenanthrene are far more complex than previously understood and that the #1778 mutant may be a good candidate for bioremediation when glucose is applied as an amendment due to its higher biosurfactant production.
Negotiating faith in exile: Learning from displacements from and into Arua, North West Uganda
Authors: Storer Elizabeth 
Published: April 2024

AbstractHumanitarians have recently championed faith actors as valuable resources in delivering humanitarian aid. Partnerships are increasingly promoted through international declarations and bespoke toolkits. Such approaches are abstracted from the historical and contemporary contexts through which faith is negotiated, and through which faith actors have become legitimate. This paper explores how faith has been entangled within the dynamics of two spatially connected crises: Ugandans fleeing post‐Amin reprisals in the mid‐1980s, and South Sudanese fleeing civil war from 2013. Drawing attention to the local‐structural engagements which have shaped forms of protection and the legitimacy of faith actors, this paper urges for a consideration of complexity in humanitarians' localisation calculations.