bluuebunny/crossref_metadata_2025_split huggingface dataset:
La société des idées. Pour une synthèse entre histoire intellectuelle et sociologie des concepts
Authors: Geroulanos Stefanos , Sapiro Gisèle 
Published: March 2024

L’histoire intellectuelle et la sociologie des intellectuels ont connu des développements séparés aux États-Unis et en France. Le présent article, issu d’une collaboration de plus de six ans ayant donné lieu à la publication du Routledge Handbook of the History and Sociology of Ideas , propose des articulations entre ces approches, tout en dressant un état des lieux des développements récents (et foisonnants) au sein de chacune d’elles. Cette divergence disciplinaire n’a pas lieu d’être et les approches peuvent au contraire se féconder mutuellement tant sur le plan méthodologique que théorique. L’histoire intellectuelle gagne à appréhender plus systématiquement le « contexte » d’énonciation en recourant au concept de champ, à l’analyse des trajectoires individuelles et collectives et à des méthodes quantitatives (par exemple l’analyse des réseaux de citations). Réciproquement, la sociologie des intellectuels qui avait par trop délaissé les contenus, s’enrichit des approches promues par la Begriffsgeschichte , l’épistémologie historique et l’École de Cambridge, partiellement introduites en France non seulement par les historiennes et historiens mais aussi par le programme d’histoire sociale des idées politiques qui suggérait déjà une telle synthèse et a œuvré en ce sens. La présente proposition l’élargit et intègre les apports de l’histoire intellectuelle étasunienne, en plein essor.
Enregistrer pour policer. Usages du registre et travail de bureau à la Lieutenance générale de police de Paris, 1730-1760
Authors: Jacquet Marie-Elisabeth , Kérien Goulven 
Published: March 2024

Actuellement conservées à la bibliothèque de l’Arsenal (BnF), les archives de la Lieutenance générale de police de Paris laissent apparaître durant les décennies 1740 et 1750 un véritable bond qualitatif des pratiques bureaucratiques de la police. L’accumulation de papiers se double en effet de la floraison d’un nouvel outil administratif, le registre, qui conduit à interroger la place des activités écrites dans les pratiques policières. Ainsi, avant même le célèbre mémoire de l’officier de la maréchaussée Guillauté en 1749, l’enregistrement s’impose comme l’instrument indispensable à la connaissance des populations parisiennes. Ce travail de bureau des policiers représente alors une dimension nouvelle et croissante de leur activité à côté de leur présence sur le terrain jusqu’alors dominante. D’abord apparu comme une nécessité dans le domaine de « la recherche des voleurs » avant le milieu du siècle, le recours aux pratiques d’enregistrement se propage ensuite plus largement dans la police dans le contexte réformateur des lieutenances de Berryer (1747-1757) et Sartine (1759-1774). Consacrant un nouveau style de police fondé sur la surveillance ciblée et l’enregistrement, il favorise à terme l’émergence d’une véritable culture policière de l’écrit. Cette évolution, forgée dans la pratique et marquée par l’empirisme et les tâtonnements, permet néanmoins à la police parisienne de devenir dans les années 1760, aux côtés de l’Armée et de la Marine, l’un des foyers d’une nouvelle culture administrative, ici au service de la régulation de l’ordre urbain dans la capitale du royaume.
Emotion Regulation, Coping Strategies, and Hazardous Drinking Among Family Caregivers of People With Alzheimer's Disease and Related Dementias
Authors: Hernandez Chilatra Jessica Andrea , Browning Wesley R. , Yildiz Mustafa , Sullivan Tami P. , Pickering Carolyn E. 
Published: March 2024

Purpose:
The current study investigated hazardous drinking and alcohol use disorders among 453 family caregivers of individuals living with Alzheimer's disease and related dementias (ADRD).

Method:
We examined the prevalence of hazardous drinking and its relationship with emotion regulation and coping strategies (problem-solving, social support, and avoidance) using data from the first wave of a longitudinal study on daily ADRD caregiving experiences. A binary logistic regression model was performed to predict the relationship between potential risk factors and hazardous drinking.

Results:
Findings revealed that 18.1% of ADRD caregivers screened positive for hazardous drinking based on the Alcohol Use Disorders Identification Test-Consumption. Caregivers experiencing greater difficulties in emotion regulation and greater reliance on avoidance as a coping strategy were at higher risk of screening positive for hazardous drinking.

Conclusion:

These findings stress the importance of targeted interventions to improve emotion regulation and reduce avoidance coping in ADRD caregivers, ultimately enhancing their well-being. [
Research in Gerontological Nursing, 17
(2), 81–90.]
Pourquoi une Généalogie de la morale ?
Authors: Salanskis Emmanuel 
Published: March 2024

Redécouvrir le projet de recherche collectif, interdisciplinaire et fondamentalement ouvert que Nietzsche a présenté dans la Généalogie de la morale en 1887 constitue la visée de ce livre. Paradoxalement, la généalogie nietzschéenne a en effet été méconnue par les premiers interprètes qui en ont fait un philosophème à part entière : en particulier par Gilles Deleuze, dont le Nietzsche et la philosophie, paru en 1962, a présenté à tort la généalogie de la morale comme un concept propre à Nietzsche. Ce n’est pas ce que nous dit Nietzsche et il est essentiel de l’entendre. Car non seulement Nietzsche se reconnaît des prédécesseurs en matière de généalogie, comme l’Allemand Paul Rée et l’Anglais Herbert Spencer, mais son intervention personnelle dans ce champ consiste bien souvent à corriger des hypothèses antérieures trop « azurées ». Il faut donc lire les auteurs que Nietzsche a lus pour mesurer ses dettes, discerner ses originalités et saisir les enjeux de son travail. On mesure ainsi le sérieux philologique de son entreprise, qui en accroît à vrai dire la portée philosophique, y compris dans une perspective contemporaine.
Life-threatening Pneumocystis jiroveci Pneumonia with Cytomegalovirus Coinfection in a Follicular Lymphoma Patient During Rituximab-based Chemotherapy
Authors: Yang Mu-Chun , Chiu Sheng-Kang , Hsiao Jong-Kai , Kao Woei-Yau 
Published: March 2024

Abstract
In the era of target therapy, we face the challenge of the risk of opportunistic infection in patients with B-cell lymphoma who receiving rituximab-based chemotherapy. Opportunistic infections such as Pneumocystis jiroveci pneumonia (PJP) and Cytomegalovirus (CMV) pneumonia are life-threatening diseases. However, PJP with CMV coinfection is rare. Here, we report a follicular lymphoma patient who suffered from PJP with CMV coinfection after receiving three cycles of rituximab, cyclophosphamide, vincristine, and prednisone regimen and was successfully rescured after timely identification and treatment. We emphasize that physicians should be alert for the coinfection of PJP and CMV in lymphoma patients receiving rituximab-based chemotherapy and the timely recognition, and treatment that may avoid a deadly outcome.
Awardee Summary of 2023 Taiwan Oncology Society Clinical Research Award Recipient: Persistent Endeavors on Research of Digestive Cancers for Three Decades
Authors: Yeh Kun-Huei 
Published: March 2024

Abstract

Objective:
Digestive cancers account for five of the top ten cancer-related deaths in Taiwan. Our team has made persistent endeavors in translational research and clinical trials of digestive cancers for almost three decades.

Data Sources and Study Selection:
We enrolled relevant translational and clinical studies for digestive cancers published by our groups in the past three decades.

Results:
First, we developed a unique weekly 24-h infusion of high-dose 5-fluorouracil (5-FU) and leucovorin regimen (HDFL) in 1992. HDFL exhibits satisfactory single-agent activity, minimal myelosuppression, and mild toxicity. A variety of HDFL-based doublet combinations (such as cisplatin-HDFL, oxaliplatin-HDFL, and paclitaxel-HDFL) have become cornerstone regimens for three decades for the treatment of gastric cancers, with high efficacy and manageable toxicity at our hospital. Second, we have made persistent efforts in translational research and clinical trials on early-stage gastric mucosa-associated lymphoid tissue lymphomas (MALTomas), gastric diffuse large B-cell lymphomas, colorectal cancers (CRCs), pancreatic cancers, and immuno-oncology. Third, on behalf of the Taiwan Oncology Society, we participated in and published the Pan-Asian adapted European Society for Medical Oncology (ESMO) Clinical Practice Guidelines for locally advanced and metastatic CRC, gastric, and esophageal cancers, and the consensus meeting on tumor-agnostic indications of microsatellite instability-high (MSI-H) and NTRK.

Conclusion:
In the future, our team will make persistent endeavors in research on digestive cancers for immunotherapy and precision medicine to further improve treatment outcomes.
Correlation of Cyclic Threshold Values Generated by GeneXpert Ultra MTB/RIF and Fluorescence Microscopy to Predict Mycobacterial Burden in Suspected Cases of Pulmonary Tuberculosis
Authors: Gota B. V. Apoorva , Shenoy Vishnu Prasad , Kamath Asha 
Published: March 2024

Abstract

Background:
Smear microscopy for acid-fast bacilli visualization is important to assess the infectivity rate in patients with pulmonary tuberculosis (PTB), but it has limited sensitivity; hence, it is important to find an alternative strategy. The aim of our study was to compare the fluorescence microscopy grading by Auramine O phenol staining technique of respiratory samples with the cyclic threshold (Ct) values of GeneXpert Ultra (Mycobacterium tuberculosis/rifampicin [MTB/RIF]) and assess the diagnostic efficacy of GeneXpert Ultra (MTB/RIF) compared to microscopy in suspected cases of PTB.

Methods:
The study was conducted in the Mycobacteriology Laboratory, Department of Microbiology, in Kasturba Hospital, Manipal. The study was a prospective, single-centered, cross-sectional study. Four hundred and fifty-two respiratory samples were included in the study. An optimal Ct cutoff value for ruling smear-positivity and smear-negativity and the mean Ct cutoff value were calculated. Clinical and radiological data from the requisition forms were assessed. IBM SPSS statistics software version 22 was used. The correlation between GeneXpert Ultra (MTB/RIF) Ct values and smear status was calculated by polychoric correlation. The extended McNemar’s test was used to find the association between the variables.

Results:
GeneXpert Ultra (MTB/RIF) yielded a higher positivity rate of 22.2% compared to smear microscopy 17.2%. Ct value and smear grading yielded a positive correlation (P = 0.8681; P < 0.05). GeneXpert Ultra (MTB/RIF) yielded nontuberculous mycobacteria in five undetected cases and speciated as Mycobacterium abscessus complex.

Conclusions:
Our study confirms the GeneXpert Ultra (MTB/RIF) Ct value levels as a predictor of smear positivity.
Analysis of the Outcomes of Tuberculosis Treatment and Factors Associated with Successful Treatment at the Bamenda Regional Hospital: A 10-year Retrospective Study
Authors: Chethkwo Fabrice , Tanih Nicoline F. , Nsagha Dickson S. 
Published: March 2024

AbstractBackground:Tuberculosis (TB) remains a global public health issue, impacting millions of people worldwide. This study determined the outcomes of TB treatment managed within a 10 year period at the Bamenda Regional Hospital in Cameroon.Methods:A retrospective study was carried out among 2428 patients diagnosed and treated for active TB infection from 2013 to 2022, at the Bamenda Regional Hospital. Data collection was done from March to April 2023 using a data extraction form. Bivariate and multivariate logistic regression models were used to identify factors associated with successful TB treatment outcomes. Data was analyzed using SPSS software version 26.Results:Of the 2428 patients with TB, 1380 (56.8%) were cured, 739 (30.4%) completed treatment, treatment failures were recorded in 10 (0.4%) patients, and 200 (8.2%) died during or after receiving treatment. Treatment default was the outcome in 99 (4.1%). Successful treatment outcomes were reported in 2119 (87.3%). Patients within age groups 41–50 (P= 0.010), 51–60 (P= 0.041), and >60 years (P= 0.006), male (P= 0.004), and human immunodeficiency virus-positive patients (P< 0.001) had decreased odds of successful treatment outcomes.Conclusion:The outcomes of treatment within a 10 year period showed that the treatment success was 2.7% below the World Health Organizations target. Prioritizing vulnerable patient groups in TB management and implementing public health interventions such as financial assistance and nutritional support will go a long way in improving treatment outcomes.
Simultaneous Maxillomandibular Distraction in Hemifacial Microsomia: A Comprehensive Review and Report of Case
Authors: Natarajan Srivalli , Deshpande Gaurav , Gandevivala Adil , Patkar Nitesh 
Published: March 2024

Abstract
Hemifacial microsomia (HFM) is a deformity of variable expressivity with unilateral hypoplasia of the mandible and the ear. Treatment of such poses a challenge as both soft and hard tissue deficiencies are to be addressed. The goal is to improve facial symmetry, allow functional jaw movement, obtain stable occlusion, and achieve patient satisfaction. This article discusses about the management of a patient with HFM using simultaneous maxillomandibular distraction also popularly known as the Oritz-Monasterio Molina technique.
A Study on Knowledge of Autism Spectrum Disorders among a Sample Population of Odisha
Authors: Barik Smitabh , Sharma Sumita , Pattanaik Sumitra , Patnaik Lipilekha 
Published: March 2024

Abstract

Background:
The number of children with autism spectrum disorders (ASD) has increased at an alarming rate in recent years. However, ASD remains undetected in developing countries like India because of lack of knowledge regarding this issue among the common people.

Objective:
The objective of this study was to assess knowledge about ASD among the general population of Odisha and the factors influencing that knowledge.

Materials and Methods:
A total of 207 people of Odisha were given a self-administered questionnaire, and knowledge was assessed based on their responses. Sociodemographic characteristics were also taken into account.

Results:
In this study, the mean age of respondents was 33.20 ± 11.63 years. Female respondents were 44.5% and male respondents were 55.5%. Females had more knowledge regarding ASD as compared to males. The knowledge regarding the etiology of ASD was poor (<50%), but the clinical features were well known to majority of participants (60%). The study population had poor knowledge (<35%) regarding diagnostic techniques of ASD. Persons who came across any autistic child in their life had a significantly higher knowledge score (16.77 ± 2.63) about ASD as compared to other people who had lack of experience (11.29 ± 4.16 with P = 0.007).

Conclusion:
There is a need of improvement in creating awareness of ASD among the general public. Areas for targeted education should be identified in order to enhance the quality of life of autistic children and their families.
Prevalence of Hypodontia in North Indian Orthodontic Subjects and its Association with Other Dental Anomalies
Authors: Mittal Vasundhra , Sehgal Vikas , Arora Priyanka , Tikoo Priyanka , Vig Sonam 
Published: March 2024

Abstract

Objectives:
The objectives of the present study were to (a) estimate the prevalence of hypodontia in permanent dentition of the North Indian Orthodontic subjects and to compare the results of the present study with specific findings of other populations; (b) evaluate occurrence of hypodontia in relation to gender, tooth type, location and pattern of distribution in maxillary and mandibular dental arches.

Materials and Methods:
Initial Pretreatment Orthodontic records of 1063 patients in the age range of 12–30 years collected from the archives of the department and the subjects who reported to the routine outpatient department of the department for orthodontic treatment and gave their consent for collecting pre–treatment orthodontic records. The initial pretreatment records to diagnose hypodontia and other dental anomalies included (a) orthodontic study models, (b) orthopantomograms, and (c) relevant findings from patient history sheets.

Results:
Thirty-two subjects fulfilled the selection criteria thus, giving the prevalence rate of hypodontia in the North Indian Orthodontic population of 3.01% out of which 21 were females and 11 were males with most common age group of 12–15 years. Maximum number of subjects were found to have only 1 CMT more commonly in the anterior region than the posterior region of the jaw and more in mandibular arch with mandibular central incisor to be the most common type of congenitally missing permanent tooth. In majority of hypodontia subjects, the most common associated dental anomaly was retained primary tooth.

Conclusion:
The prevalence of hypodontia of this study was within the range of that reported in the literature. Prompt diagnosis of hypodontia and other anomalies at an early age can help in planning various treatment modalities with a multidisciplinary team approach to establish a functional and esthetic dentition.
Dentinogenesis Imperfecta: A Case Report and Review
Authors: Sonar Prasanna Ravindra , Panchbhai Aarati S. 
Published: March 2024

Abstract
Dentinogenesis imperfecta (DI) is a condition that affects both the primary teeth and the permanent teeth and is autosomal dominant. Opalescent teeth made of irregularly shaped and less mineralized dentin that obliterate the pulp chambers and canals characterize this localized mesodermal dysplasia, which develops in the absence of any underlying systemic illness. In this article, the clinical signs and radiological features of DI are reviewed briefly. We are presenting a case of DI Type-II (DI1) that occurred in an Indian family over two generations.
Promoting Health and Well-being of Institutionalized Destitute Females: A Study from Thar Region of India
Authors: Sharma Himani , Joshi Nitin Kumar , Jain Yogesh Kumar , Bhardwaj Pankaj 
Published: March 2024

Abstract

Context/Background:
Destitute females are largely neglected by society and lead a miserable life, subject to mental and physical abuse. The study was planned to assess the basic health needs of females living in a destitute home and develop a model information, education, and communication (IEC) tool kit package for the specific needs to facilitate better mental and physical well-being.

Aims/Objectives:
This study aims to develop a model IEC toolkit package for specific health needs of females living in destitute homes.

Methodology:
A multiphasic mixed-methods study was conducted at the destitute home of Jodhpur. Females living in the facility were interviewed to assess their basic health needs and an IEC model toolkit was prepared for health promotion. The toolkit was implemented and feedback was taken to refine the final model toolkit.

Results:
All 31 females were included in the study after due consent. The mean age was 31 years (standard deviation = 7.6) and majority (10; 32.3%) were literate with no formal education. Through interviews, priority health needs were derived as mental health, menstrual hygiene, and general hygiene. Interventions designed were yoga, recreation, laughter club and anger coping skills for mental health, visual aids, role plays, and posters for menstrual and general hygiene. The final model was designed specifically for literacy levels using feedback from stakeholders.

Conclusions:
The developed model was received with enthusiasm by participants and implementers. It was deemed to lessen their burden in a long run, ensuring sustainability. Such model is easily implementable and could be replicated by other destitute homes for health promotion amongst destitute females.
Detection of KRAS Mutations in Triple-negative Breast Cancers by Polymerase Chain Reaction
Authors: Vodithala Sahitya , Bhake Arvind 
Published: March 2024

Abstract

Background:
Recently, it has been proven that KRAS gene mutation analysis is an additional in vitro diagnostic method for determining colorectal cancer patients who will not respond to anti-epidermal growth factor receptor (EGFR) therapy. KRAS mutation status assessment may be important in other EGFR-overexpressed cancers, such as breast cancer tumors. Only 5% of breast tumors are KRAS-mutated, yet 60% of triple-negative breast tumors express EGFR, making them potential targets for EGFR inhibitors. To provide a biological foundation for assessing anti-EGFR therapy, we aimed to examine the frequency of KRAS mutations in triple-negative breast cancer (TNBC).

Materials and Methods:
Forty breast cancer cases were evaluated. These 40 cases have undergone immunohistochemistry for estrogen receptor, progesterone receptor, and human epidermal growth factor receptor 2 markers which exhibited a negative reaction and were ascertained as triple negative. The mutation status of KRAS was determined by real-time polymerase chain reaction (RT-PCR) to detect wild or mutant types of KRAS.

Results:
In our study, we observed that, out of the total 40 cases of TNBCs, 14 (35%) cases were of wild type and 26 (65%) cases were mutant type detected by RT-PCR.

Conclusion:
According to our study, KRAS mutations were detected in TNBCs, and EGFR inhibitors may be effective in the treatment of these tumors, which overexpress EGFR in around 65% of cases.
A Comparative Study of Serum Butyric Acid in Subjects with Tongue Cancer
Authors: Suhasini P. C. , Shetty Shilpa S. , Shetty Vijith Vittal , Bhat Vadisha , Roopashree P. G. , Kumari N. Suchetha 
Published: March 2024

Abstract

Aim:
The aim of the study was to study the level of butyric acid in tongue cancer subjects.

Materials and Methods:
Thirty controls and 30 tongue cancer subjects were recruited for the study. Serum butyric acid levels were estimated using ELISA kits. Statistical analyses were done using SPSS vs 22. The Mann–Whitney U and Kruskal–Wallis tests were used. P ≤ 0.05 was considered statistically significant.

Results:
Butyric acid levels were significantly higher in control subjects when compared to case subjects.

Conclusion:
Butyric acid could be used as a potential anticancer agent in tongue cancer treatment.