bluuebunny/crossref_metadata_2025_split huggingface dataset:
Cross‐Continental Shifts of Ecological Strategy in a Global Plant Invader
Authors: Irimia Ramona E. , Zhao Weihan , Cao Peipei , Parepa Madalin , Liao Zhi‐Yong , Wang Shengyu , Mounger Jeannie M. , Richardson Conner , Elkott Fatima , Zhuang Xin , Bi Jingwen , Jin Jieren , Zhao Yujie , Kugler Elodie , Rafalski Julia , Schloter Eva , Wu Jihua , Ju Rui‐Ting , Yang Ji , Chumová Zuzana , Trávníček Pavel , Li Bo , Bossdorf Oliver , Richards Christina L. 
Published: February 2025

ABSTRACTAimPlant invasions are a global problem that requires studying plants and their environmental associations across native and introduced ranges.Location2000 km transects in China, Europe and North America.Time PeriodJune 2019–July 2020.Major Taxa StudiedJapanese knotweed (Reynoutria japonica).MethodsWe surveyed 150 populations of Japanese knotweed, a noxious invader of the temperate zone, along 2000 km transects in native China and the introduced ranges of Europe and North America.ResultsWe found that larger plants and denser populations in the introduced ranges were associated with shifts in leaf economy and chemical defences. Introduced knotweed populations had higher SLA but reduced leaf chlorophyll, lignin, C:N ratio and leaf toughness along with altered leaf tannins, flavonoids and alkaloids. We found three distinct multivariate knotweed phenotypes primarily in the introduced ranges, and two multivariate knotweed phenotypes mainly in native populations.Main ConclusionsDecreased herbivore and pathogen impacts in introduced populations and changes in environmental associations indicate that enemy release and novel habitat conditions might have driven the emergence of novel ecological strategies in this global plant invader.
Association between school bullying and late‐life depression: Evidence from the China health and retirement longitudinal study
Authors: Zuo You , Liu Lan , Chen Gong , Huang Guogui 
Published: February 2025

BackgroundExisting literature suggests that school bullying can have long‐lasting effects on mental health, but its specific impact on late‐life depression remain underexplored. This study aims to investigate the association between early‐life school bullying experiences and depression symptoms in old age and the variations by sex, place of residence and educational level.MethodData were derived from the Life History Survey of the China Health and Retirement Longitudinal Study in 2014, including 4333 older adults aged ≥60 years. School bullying was assessed on the basis of self‐reported experiences during childhood. Depression symptoms were measured using the Center for Epidemiologic Studies Depression Scale‐10. Poisson regression analyses were performed to examine the relationship between early‐life school bullying experience and late‐life depression.ResultsOf the 4333 respondents, 607 (14%) reported being bullied during childhood, and 1274 (29.4%) exhibited symptoms of depression. Older adults who experienced school bullying were 1.17 times more likely to exhibit depression symptoms compared with those without such experiences (prevalence ratio [PR], 1.173; 95% confidence interval [CI], 1.027–1.3390). This association was more prominent among women (PR, 1.284; 95% CI, 1.093–1.475), rural residents (PR, 1.477; 95% CI, 1.210–1.803) and those with education at primary school level (PR, 1.172; 95% CI, 1.017–1.352). The results remained robust using an alternative school bullying cutoff and after imputing all missing data.ConclusionEarly‐life school bullying is a significant risk factor for depression in later life, with its impact being particularly pronounced among women, rural residents and those with lower educational levels. These findings highlight the need for targeted mental health interventions for individuals with a history of early‐life school bullying to mitigate long‐term psychological effects. Geriatr Gerontol Int 2025; ••: ••–••.
Co‐Design of the Structured Personalised Assessment for Reviews After Cancer (SPARC) Intervention
Authors: Adam Rosalind , Duncan Lisa , MacLennan Sara , Locock Louise , Kiltie Anne E. , Samuel Leslie , Murchie Peter 
Published: February 2025

ABSTRACTIntroductionAn increasing number of people are living beyond cancer with unmet health needs. The aim of this study was to co‐design a digital intervention to improve health outcomes for people who have completed potentially curative treatment for cancer.MethodsTwo co‐design workshops were held with patients, clinicians (including oncologists, general practitioners and nurses), digital/computing science experts and third‐sector representatives. At workshop one, problems and gaps in care were identified and intervention ideas were generated. At workshop two, a prototype intervention was discussed and refined.ResultsThe workshops were attended by 43 people in total: 26 at event one and 23 at event two (six attended both events). Patients valued relationship‐based care and felt supported during hospital treatment. Patients ‘fell off a cliff’ after discharge, and there was consensus that more could be done in primary care to support those living beyond cancer. It was proposed that cancer reviews could be integrated into UK primary care chronic disease management activities. A digital form, the ‘Structured Personalised Assessment for Reviews after Cancer’ (SPARC) tool, was developed to support asynchronous consultations that would cover the breadth of problems and health promotion activities required for high‐quality primary care for cancer. SPARC could also identify those without problems who do not require review.ConclusionSPARC has been co‐designed to support brief but comprehensive cancer review consultations between primary care clinicians and their patients. SPARC aligns with best practice guidelines. The next step is to evaluate SPARC with patients and in general practices.Patient and Public ContributionPatient and stakeholder engagement was at the centre of this research study. Cancer organisations such as ‘CLAN’ cancer support, Prostate Cancer Scotland and Cancer Research UK helped us to engage with patients. The Aberdeen University Institute of Applied Health Science Patient Public Involvement group were also instrumental in sense‐checking and improving the materials for the second workshop. We plan to involve our patient and carer partners in designing the next stages of our research (including study materials, processes and methods) so that they will be at the centre of evaluating the intervention that they have been instrumental in designing.
The Machiavellian, Narcissistic, and Psychopathic Consumers: A Systematic Review of Dark Triad
Authors: Khan Fateh Mohd , Khan Areeba , Ahmed Sabara Soyafuddin , Naz Ariba , Salim Mairaj , Zaheer Asma , Rashid Umra 
Published: February 2025

ABSTRACTThe term dark triad is an assemblage of the three dark personality traits, that is, Machiavellianism, Narcissism, and Psychopathy. Recently, these traits have gained prominence as both direct and indirect antecedents of consumption‐related constructs in marketing literature, signalling heightened scholarly interest in marketing and consumer behaviour. This study adopts a hybrid systematic review methodology, considered a two‐pronged approach comprising framework‐based systematic review and bibliometric review methods, analysing 251 articles sourced from two of the largest citation and abstract databases: Web of Science and Scopus. We offered a panoramic overview of the domain of dark triad in marketing and consumption research, using selected techniques from the bibliometric toolbox (e.g. cartographic analysis, charting of publication‐related metrics, mapping of citation‐related metrics and visualisation) and TCM framework‐based content analysis. First, we uncovered the performance trends depicting key trends in the domain. Second, we deciphered the intellectual structure by delineating and elaborating on themes such as (1) Psychopathy, (2) Narcissism, (3) Materialism, and (4) Machiavellianism. Additionally, we charted theoretical perspectives, contextual settings and methodological approaches deployed in the domain of the dark triad in marketing and consumption research. These findings further paved the way for orchestrating a rich future research agenda and interesting insights (implications) for practitioners and academics.
Ureteral contrast findings as a potential predictor for invasive intervention in high‐grade pediatric renal trauma: A retrospective analysis
Authors: Lui Hansen , Kim Phillip J. , Kang Lisa H. , Durbin‐Johnson Blythe P. , Kurzrock Eric A. 
Published: February 2025

ObjectivesTo determine if patient variables were associated with intervention in pediatric patients presenting with high‐grade renal injuries.MethodsA retrospective review of pediatric patients presenting with grade IV/V renal injury between 2003 and 2021 at a Level 1 trauma center was performed. Renal injury grade was verified and updated based upon the 2018 American Association for the Surgery of Trauma injury scale. Multivariable logistic regression analyses were performed.ResultsSeventy‐five patients (median age 13 years old, IQR 9–16) with Grade IV (n = 53) or Grade V (n = 22) injury were identified. 33% (25/75) had immediate renal intervention within 24 h of admission. Of the remaining 50 children who were observed, 47 had blunt trauma, and outcomes were analyzed. The median age of observed patients was 12 years (IQR 8–14) and 30% (14/47) had intervention. Delayed images on CT showed ureteral contrast was present in 87% (41/47) of observed patients. Multivariable analysis demonstrated that the presence of contrast in the ureter is associated with significantly lower odds of intervention, OR 0.06 [0–0.73, 95% CI], p = 0.03.ConclusionAfter grades IV and V blunt renal injury, for those children who are considered safe to observe, AAST grade of injury did not associate with procedural intervention. The presence of contrast in the ureter on delayed CT imaging was associated with a significantly lower odds of procedural intervention.
Innate Immune Receptors as Dynamic Modulators of Extrafollicular Autoimmune B Cell Response
Authors: Zhu Danni Yi‐Dan , Castrillon Carlos , Carroll Michael C. 
Published: February 2025

ABSTRACTThe immune system relies on carefully calibrated cellular machineries to enable distinction between endogenous and foreign molecules, with autoimmunity arising when this balance is disrupted. As potent autoantibody factories, B cells are major drivers of many autoimmune diseases. A significant fraction of patients affected by chronic autoimmune diseases such as systemic lupus erythematosus (SLE) exhibit pathogenic accumulation of B‐cell subsets that are believed to be derived from the extrafollicular (EF) differentiation pathway. These B‐cell subsets, although variously named and exhibiting intrinsic heterogeneity, are all poised producers of autoantibodies that correlate with patient pathophysiology. In addition, they are often characterized by biomarkers known to drive the innate immune response, including toll‐like receptors and complement receptors. Although many innate receptors have well‐established functions in myeloid cells and other immune cell types, their B cell‐specific functions are still under active investigation and are crucial for understanding the molecular pathways that drive B‐cell breaks of tolerance. In this review, we summarize studies on innate immune receptors that serve prominent roles in regulating EF B‐cell activation in health and autoimmunity. By discussing independent and collaborative functions of these receptors, we hope to provide new perspectives in autoimmune disease signature research.
Molar volume model for olivine solution
Authors: Kang Yoongu , Jung In‐Ho 
Published: February 2025

AbstractA new molar volume model for multicomponent olivine solid solutions, considering the linear summation of molar volumes of individual configurations weighted by their respective cation distribution fractions, is developed in this study. The model encompasses four possible configurations within olivine, each involving two distinct divalent ions occupying two different sites. Using available experimental data and employing the compound energy formalism to calculate cation distribution fractions, the study derives temperature‐dependent molar volume expressions for various olivine configurations. Strong correlations between the estimated molar volume and the effective ionic radii of constituent cations are established, allowing for the estimation of molar volume for olivine configurations without experimental data. The results provide a robust framework for accurately estimating the molar volume of olivine across diverse compositions and temperatures, enhancing our understanding of its thermal expansion characteristics. Moreover, these estimated molar volume expressions and observed correlations enable comprehensive insights into the thermal expansion behavior of multicomponent olivine solid solutions.
Health Knowledge Acquisition and Health Communication Ability of Nurses: A Chain Mediating Model of Health Literacy and Health Education Competence
Authors: Liu Congying , Chen Zhiqian , Qin Han , Yang Ya , Cui Xiaoling , Lei Ruifang , Li Baohua 
Published: February 2025

ABSTRACTBackgroundThe health communication ability of nurses significantly impacts patients' health positively. A strong knowledge base is essential for nurses to deliver high‐quality health communication.AimThis study aims to explore the mechanisms linking nurse health knowledge acquisition and health communication ability.DesignA cross‐sectional study.MethodsThis cross‐sectional study utilised convenience sampling of 667 nurses from nine county‐level hospitals. Questionnaires were used to assess health knowledge acquisition, health literacy, health education competence and health literacy communication ability in nurses. Structural equation modelling was employed to investigate the mechanisms linking nurse health knowledge acquisition and health literacy communication ability.ResultsThe correlation analysis revealed significant positive relationships among nurses' health knowledge acquisition, health literacy, health education competence and health communication ability. The chain‐mediating model indicated that health knowledge acquisition significantly influences health communication ability, with a total effect, comprising a direct effect and an indirect effect. The indirect effects were mediated either independently by health education competence or through a combination of health literacy and health education competence.ConclusionA structural equation model was developed to provide a comprehensive framework for understanding the complex interplay among nurses' health knowledge acquisition, health literacy, health education competence and health communication ability. The model demonstrates that health knowledge acquisition has a significant overall effect and indirect effect on the improvement of health communication ability. Assisting nurses in translating health knowledge into health literacy may be a crucial step in enhancing their competence in health education.ImpactThese findings enhance our understanding of the predictive effects of health knowledge acquisition on health communication ability and offer practical implications for the promoting and intervening in the health communication ability of nurses.Reporting MethodSTROBE statement.Patient or Public ContributionNo patient or public contribution.
A Comparison of Patient Self‐Reported Fatigue in the FRAIL Scale With a Validated Fatigue Measure
Authors: Kumar Saloni , des Bordes Jude K. , Khan Raia , Jantea Rachel , Fu Sunyang , Kwak Min Ji , Rianon Nahid J. 
Published: February 2025

ABSTRACTRationaleThe FRAIL scale is a self‐administered tool used to screen for frailty in clinical, community and long‐term nursing settings. Patient's self‐reporting of fatigue in the FRAIL scale may raise concerns of subjectivity and accuracy in frailty assessment.ObjectiveTo assess the performance of the patient‐reported fatigue measure in the FRAIL scale in comparison to a validated fatigue measure, the Fatigue Severity Scale (FSS).MethodsWe conducted a cross‐sectional study involving interviews and medical records review. Participants were 55 years and older seen at an ambulatory geriatric osteoporosis clinic. Participants were administered the FRAIL scale and the FSS over the phone or in person. Patient self‐reported fatigue was derived from the first item (Are you fatigued?) on the FRAIL scale while the FSS provided a validated fatigue measure. Clinical and demographic data were obtained by review of medical records. Sensitivity, specificity, negative and positive predictive values, and AUC were estimated for patient self‐reported fatigue from the FRAIL scale using the FSS as the gold standard. Logistic regression analysis was used to investigate independent associations between the items on the FRAIL scale and fatigue assessed by the FSS, adjusting for demographic and clinical characteristics.ResultsWe interviewed 126 participants, mean age was 77.2 ± 8.5 years, 91.3% (116) were female and 69.3% (88) were Caucasian/White. The prevalence of fatigue assessed by the FSS and the FRAIL scale were 24% and 34.6%, respectively. The sensitivity, specificity, positive predictive value, and negative predictive value of patient‐reported fatigue were 0.67, 0.75, 0.45, and 0.88, respectively. The AUC was 0.71. Depression (OR = 2.41, 95% CI = 1.14–10.25) and patient self‐reported fatigue (OR = 4.74, 95% CI = 1.74–12.9) were significantly associated with FSS fatigue measure.ConclusionPatient‐reported fatigue largely reflects validated measure of fatigue. Physicians should therefore be encouraged to use the FRAIL scale to assess frailty.
A common garden experiment in the wild reveals heritable differences in migration tendencies among brown trout populations
Authors: Reed Thomas E. , Wynne Robert , Coughlan Jamie , Gargan Patrick , Kaufmann Joshka , Phillips Karl. P. , Rinaldo Adrian , Poole Russell , McGinnity Philip 
Published: February 2025

AbstractWe undertook a common garden experiment in the Burrishoole catchment, western Ireland, to test for heritable life‐history differences among neighboring brown trout (Salmo trutta L.) populations that exhibit neutral genetic divergence. Experimental crosses were made using either local females (obtained from a below‐waterfalls section of the Rough River within the Burrishoole) or females from the Erriff River—a neighboring catchment that currently produces a stronger run of anadromous migrants than the Burrishoole. Each female was mated to three different types of males: Rough Below‐Falls, Rough Above‐Falls (resident males obtained from above the waterfalls), and Erriff. Offspring from the resulting six crosses were introduced as unfed fry into a stretch of the Rough River bounded upstream by the waterfalls and downstream by a Wolf‐type fish trap (Rough River Downstream Trap, RRDT). Genetic parentage analysis (16 microsatellite markers) was then used to assign offspring sampled at various time points and locations back to cross type. No differences in parr survival rates (electrofishing in the Rough River) were found among the crosses, but parr moving downstream (intercepted at the RRDT) were skewed toward the Erriff female × Erriff male cross, with a deficit assigning to the Rough Below‐Falls female × Rough Above‐Falls male cross. Smolts leaving fresh water (sampled at two sea‐entry traps) were assigned disproportionately to crosses involving one or two Erriff parents. Offspring from pure Burrishoole crosses were more likely to become putative spawners than those from crosses involving one or two Erriff parents, pointing toward possible local adaptation. These results are consistent with heritable variation in migratory tendencies—a key aspect of intraspecific biodiversity that warrants protection—and with previous suggestions that the Burrishoole system may have evolved recently toward reduced anadromy following a novel and catastrophic anthropogenic change.
Genetic Markers of Postmortem Brain Iron
Authors: Cornelis Marilyn C. , Fazlollahi Amir , Bennett David A. , Schneider Julie A. , Ayton Scott 
Published: February 2025

ABSTRACTBrain iron (Fe) dyshomeostasis is implicated in neurodegenerative diseases. Genome‐wide association studies (GWAS) have identified plausible loci correlated with peripheral levels of Fe. Systemic organs and the brain share several Fe regulatory proteins but there likely exist different homeostatic pathways. We performed the first GWAS of inductively coupled plasma mass spectrometry measures of postmortem brain Fe from 635 Rush Memory and Aging Project (MAP) participants. Sixteen single nucleotide polymorphisms (SNPs) associated with Fe in at least one of four brain regions were measured (p < 5 × 10−8). Promising SNPs (p < 5 × 10−6) were followed up for replication in published GWAS of blood, spleen, and brain imaging Fe traits and mapped to candidate genes for targeted cortical transcriptomic and epigenetic analysis of postmortem Fe in MAP. Results for SNPs previously associated with other Fe traits were also examined. Ninety‐eight SNPs associated with postmortem brain Fe were at least nominally (p < 0.05) associated with one or more related Fe traits. Most novel loci identified had no direct links to Fe regulatory pathways but rather endoplasmic reticulum‐Golgi trafficking (SORL1, SORCS2, MARCH1, CLTC), heparan sulfate (HS3ST4, HS3ST1), and coenzyme A (SLC5A6, PANK3); supported by nearest gene function and omic analyses. We replicated (p < 0.05) several previously published Fe loci mapping to candidate genes in cellular and systemic Fe regulation. Finally, novel loci (BMAL, COQ5, SLC25A11) and replication of prior loci (PINK1, PPIF, LONP1) lend support to the role of circadian rhythms and mitochondria function in Fe regulation more generally. In summary, we provide support for novel loci linked to pathways that may have greater relevance to brain Fe accumulation; some of which are implicated in neurodegeneration. However, replication of a subset of prior loci for blood Fe suggests that genetic determinants or biological pathways underlying Fe accumulation in the brain are not completely distinct from those of Fe circulating in the periphery.image
Corticotropin‐releasing hormone receptor 1 mediates the enhanced locomotor activity and metabolic demands to an acute thermal stress in adult zebrafish
Authors: Shvartsburd Zachary , Vijayan Mathilakath M. 
Published: February 2025

AbstractWe recently showed that Crh‐Crhr1 signalling is essential for acute stress‐related locomotor activity in zebrafish larvae. However, the possibility that Crhr1 activation may also initiate the acute metabolic demands for stress coping was unexplored. Here, we tested the hypothesis that Crhr1 signalling is essential for the thermal stressor‐induced increases in the acute metabolic rate, a key response for coping with the enhanced energy demands during stress. We tested this by using a wildtype (WT) and a ubiquitous Crhr1 knockout (crhr1−/−) zebrafish and subjecting them to an acute thermal stressor (TS: +5°C above ambient for 60 min). The TS induced the heat shock proteins response in both genotypes, but the elevated cortisol response observed in the WT was absent in the crhr1−/− mutant. The TS also increased the locomotor activity and the metabolic rate in the WT fish, but this response was inhibited in the crhr1−/− mutants. To test if this was due to a lack of TS‐induced cortisol elevation in the crhr1−/− mutant, we mimicked the response in the WT fish by treating them with metyrapone, an 11β‐hydroxylase inhibitor. While metyrapone inhibited the TS‐induced cortisol elevation in the WT, it did not affect the metabolic rate. The lack of Crhr1 also reduced the swimming performance, and the lower Ucrit in the mutants corresponded with alterations in muscle energy metabolism. Together, our results indicate that Crh‐Crhr1 signalling, independent of downstream cortisol action, is essential for the TS‐induced acute hyperlocomotor activity and the associated increases in the metabolic demand for stress coping.