bluuebunny/crossref_metadata_2025_split huggingface dataset:
Community pharmacist-led point-of-care eGFR screening: early detection of chronic kidney disease in high-risk patients
Authors: Jairoun Ammar Abdulrahman , Al-Hemyari Sabaa Saleh , Shahwan Moyad , Zyoud Samer H. , El-Dahiyat Faris 
Published: March 2024

AbstractAdherence to scheduled physician screenings for renal function monitoring in patients with chronic kidney disease (CKD) or those at high risk remains suboptimal despite the endorsement of regular screenings by several clinical practice guidelines. Our study aims to assess the effectiveness of a point-of-care CKD screening program led by these pharmacists using the PICCOLO device while recognizing the unique position of community pharmacists in primary care. We conducted an 11-month prospective point-of-care interventional research study in the United Arab Emirates to evaluate the performance of a community pharmacist-led CKD screening program for high-risk patients. Six diverse community pharmacies were selected based on staff availability, patient volume, and their offered range of services. Eligible individuals with risk factors for CKD were identified during medication evaluations. The PICCOLO Comprehensive Metabolic Panel facilitated on-site blood analysis, delivering estimated Glomerular Filtration Rate (eGFR) results within 10 to 15 min. Data also included eGFR categories, demographic information, and insights into lifestyle and health habits collected through a questionnaire. Pharmacists conducted comprehensive medication reviews and offered referrals and lifestyle guidance as part of the program. The study encompassed a total of 400 patients, with an average age of 69 ± 13.4 years within the study cohort. Notably, 38.8% (155 individuals) of the 400 patients were found to have undiagnosed CKD stages 3–5. Univariate logistic regression analysis revealed a significant association between a higher incidence of CKD stages 3–5 and factors such as older age, a history of hypertension, vascular disease, and diabetes mellitus. In the multivariate regression model, age and a history of diabetes mellitus emerged as significant predictors of an elevated risk of CKD. This study sheds light on the viability and impact of CKD screening programs conducted by community pharmacists, particularly in detecting CKD stages 3–5. The findings have implications for healthcare policies, as they can influence the enhancement of early detection and management of CKD. Moreover, these insights may catalyze focused screening initiatives and strengthen collaboration between community pharmacies and healthcare systems to benefit patients at high risk of CKD.
Analytical formulation of spatiotemporal modulated graphene-based waveguides using Floquet-Bloch theory
Authors: Valizadeh Mahsa , Yousefi Leila , Miri MirFaez 
Published: March 2024

AbstractIn this work, an analytical model to study graphene-based spatiotemporal modulated structures is developed and verified through comparison with full wave numerical simulations. Graphene is an ideal material for realizing spatiotemporal modulated structures at high frequencies of THz and optics. In this analysis, the electromagnetic response of studied structures is expressed in terms of weighted Floquet-Bloch modes supported by the structure, while graphene is modeled by a spatiotemporal modulated surface current that imposes certain boundary conditions on the modes. The developed analytical technique is a comprehensive tool and can be used for accurate modeling of different kinds of spatiotemporal devices including lossy, guided, and leaky wave structures. To demonstrate the accuracy of the model, two plasmonic waveguides with space and time modulated graphene conductivity are analyzed and their interband and intraband transition between modes are thoroughly investigated. Using the developed analytical model, spatiotemporal modulation phenomena such as mode conversion, wave amplification and nonreciprocal response are explored and discussed for the studied structures.
Circulating TNF receptor levels are associated with estimated glomerular filtration rate even in healthy individuals with normal kidney function
Authors: Gohda Tomohito , Murakoshi Maki , Shibata Terumi , Suzuki Yusuke , Takemura Hiroyuki , Tsuchiya Koji , Okada Tomoki , Wakita Mitsuru , Horiuchi Yuki , Tabe Yoko , Kamei Nozomu 
Published: March 2024

AbstractThe association between serum tumor necrosis factor receptor (TNFRs: TNFR1, TNFR2) levels and estimated glomerular filtration rate (eGFR) observed in patients with diabetes has not been comprehensively tested in healthy subjects with normal kidney function. It also remains unclear whether TNFR levels differ by age and sex, and between healthy subjects and diabetics. We measured serum TNFR levels in 413 healthy subjects and 292 patients with type 2 diabetes. In healthy subjects, TNFR levels did not differ between men and women. Additionally, TNFR2, but not TNFR1, levels increased with age. In multivariate analysis, TNFR1 was associated only with cystatin C-based eGFR (eGFR-CysC), whereas TNFR2 was associated with systolic blood pressure in addition to eGFR-CysC. Both TNFRs were associated with lower eGFR (eGFR-Cys < 90 mL/min/1.73 m2) even after adjustment for relevant clinical factors. Upon combining healthy subjects and patients with diabetes, the presence of diabetes and elevated glycated hemoglobin level were significant factors in determining TNFR levels. TNFR levels were associated with eGFR-CysC, but were not affected by age and sex in healthy subjects with normal kidney function. TNFR levels in patients with diabetes appeared to be higher than in healthy subjects.
Prefeeding of Clarias gariepinus with Spirulina platensis counteracts petroleum hydrocarbons-induced hepato- and nephrotoxicity
Authors: Sayed Alaa El-Din H. , Khalil Nasser S. Abou , Alghriany Alshaimaa A. I. , Abdel-Ghaffar Sary Kh. , Hussein Asmaa A. A. 
Published: March 2024

AbstractPetroleum aromatic hydrocarbons are considered one of the most dangerous aquatic pollutants due to their widespread across water bodies, persistence, and extension to the food chain. To our knowledge, there hasn’t been any research investigating the hepatorenoprotective effects of Spirulina platensis (SP) against toxicity induced by these environmental toxicants in fish. Thus, we decided to explore its potential safeguarding against benzene and toluene exposure in adult Clarias gariepinus. To achieve this objective, fish were divided into five groups (60 per group; 20 per replicate). The first group served as a control. The second and third groups were intoxicated with benzene and toluene at doses of 0.762 and 26.614 ng/L, respectively for 15 days. The fourth and fifth groups (SP + benzene and SP + toluene, respectively) were challenged with benzene and toluene as previously mentioned following dietary inclusion of SP at a dose of 5 g/kg diet for 30 days. The marked increase in liver metabolizing enzymes, glucose, total protein, albumin, globulin, albumin/globulin ratio, and creatinine confirmed the hepato- and nephrotoxic impacts of benzene and toluene. These outcomes were coupled with cytopathological affections and excessive collagen deposition. The incorporation of SP in ration formulation, on the contrary, restored the previously mentioned toxicological profile due to its antioxidant and cytoprotective attributes. Regardless of SP intervention, the renal tissues still displayed histo-architectural lesions, because of insufficient dose and timeframe. Additional research will be required to identify the ideal SP remediation regimen.
Associations between objectively measured overall and intensity-specific physical activity and phase angle in older adults
Authors: Chen Jiaren , Lai Ting-Fu , Lin Chien-Yu , Hsueh Ming-Chun , Park Jong-Hwan , Liao Yung 
Published: March 2024

AbstractPhase angle (PhA) is an indicator of cellular health and is positively associated with overall physical activity (PA). However, varied associations between different intensities of PA and PhA by body segment in older populations remain unexplored. We investigated the associations between overall and different intensities of PA and upper-, lower-, and whole-body PhA in older adults. Overall exposure to light-intensity (LPA), moderate-intensity (MPA), and vigorous-intensity physical activity (VPA) was assessed using a triaxial accelerometer (GT3X + , ActiGraph). The outcome variables were upper-, lower-, and whole-body PhA measured using bioelectrical impedance analysis (MC-780MA, TANITA). Multiple linear regression helped examine the associations between the exposure and outcome variables after adjusting for age, gender, body mass index, and accelerometer wear time. A cross-sectional analysis involved 166 community-dwelling older participants (mean age = 72.1 ± 5.5 years; 78.3% women). Overall PA was associated with larger upper- (B: 0.057, 95% confidence interval [CI] 0.018–0.095) and whole-body PhA (B: 0.044, 95% CI 0.006–0.081). LPA was associated with larger upper-body PhA (B: 0.059, 95% CI 0.017–0.101), and MPA was associated with larger lower- (B: 0.273, 95% CI 0.128–0.419) and whole-body PhA (B: 0.141, 95% CI 0.002–0.280). VPA and PhA were not associated. Future interventions targeting PhA in older adults should consider the differential impact of PA intensity on various body segments of the PhA.
Association between general self-efficacy and health literacy among stroke survivors 1-year post-discharge: a cross-sectional study
Authors: Hess Engström Andrea , Flink Maria , Lindblom Sebastian , von Koch Lena , Ytterberg Charlotte 
Published: March 2024

AbstractStroke may affect physical functioning, cognition, and mental and social aspects of one’s life. Health literacy and self-efficacy are associated with positive health outcomes and are important factors for managing the diverse consequences of a stroke. However, there is very little literature on the association between health literacy and self-efficacy. This study aimed to investigate the association between health literacy and self-efficacy among stroke survivors 1 year after discharge from hospital. Participants in this cross-sectional study were patients diagnosed with a stroke, mainly a mild stroke, who were referred to rehabilitation in primary care after discharge from hospital in Sweden. Data was collected using questionnaires, performance-based tests, and medical records. Ordinal logistic regression was used to analyze the association between general self-efficacy and health literacy in adjusted models. The analysis revealed that higher levels of general self-efficacy and higher levels of performing activities of daily living were associated with higher levels of health literacy. Stroke survivors with higher general self-efficacy also report higher health literacy 1-year post-discharge from hospital. Future studies should focus on the pathways by which health literacy and general self-efficacy work among stroke survivors and in populations with low health literacy, severe stroke or significant cognitive impairments.
Research on the dynamic behavior of flexible drilling tools in ultrashort-radius radial horizontal wells
Authors: Lin Zhiqiang , Luo Min , Wang Jing , Xiu Tingting , Li Qiaozhen 
Published: March 2024

AbstractA flexible drilling tool is a special drilling tool for ultrashort-radius radial horizontal wells. This tool is composed of many parts and has the characteristics of a multibody system. In this paper, a numerical method for the dynamic analysis of flexible drilling tools is proposed. The flexible drill tool is discretized into spatial beam elements, while the multilayer contact of the flexible drilling tool is represented by the multilayer dynamic gap element, and the dynamic model of the multibody system for the flexible drilling tool’s multilayer contact is established, considering the interaction force between the drill bit and the rock. The nonlinear dynamic equation is solved using the Newmark method and Newton–Raphson method. An analysis of the dynamic behavior of a flexible drilling tool is conducted. The results indicate that the flexible drilling tool experiences vortex formation due to the interaction between the flexible drilling pipe and the guide pipe, leading to increased friction and wear. This situation hinders safe drilling operations with flexible drilling tools. The collision force of the flexible drilling tool near the bottom of the hole is more severe than that of the other tool types, which may lead to failure of the connection.
Experimental and theoretical aspects of the growth of vertically aligned CNTs by CCVD on AZO substrate
Authors: Nánai Lilla , Németh Zoltán , Kaptay George , Hernadi Klara 
Published: March 2024

AbstractAn efficient and reproducible growth of vertically aligned carbon nanotubes by CCVD requires accurate and specific setting of the synthesis parameters and the properties of catalyst thin layers. In this work, the growth of vertically aligned carbon nanotubes onto AZO (= aluminum doped zinc oxide) glass substrate covered by Al2O3 and Fe-Co catalyst layer system is presented. Investigation of the effect of catalyst composition and synthesis temperature on CVD growth revealed the optimum condition of the synthesis. The analysis of as-prepared samples by SEM, TEM and Raman spectroscopy was carried out to prove the structure and quality of carbon deposit. Theoretical considerations have supported speculative ideas about the role of the support layer, the transformation of the catalyst layer in the presence of hydrogen gas and the growth mechanism of carbon nanotubes. The mechanism of CNT growth is modelled and the order of magnitude of experimentally observed vertical linear growth rate of CNT (several nm/s) is reproduced.
Collaborative optimization of depot location, capacity and rolling stock scheduling considering maintenance requirements
Authors: Zhong Qingwei , Yu Yingxue , Huang Yiru , Li Wenxin , Zhang Yongxiang , Yan Xu 
Published: March 2024

AbstractGenerally, when optimizing a rolling stock schedule, the locations of the depots, or places in the network where the composition changes and maintenance occurs, are assumed known. The locations where maintenance is performed naturally influence the quality of any resulting rolling stock schedules. In this paper, the problem of selecting new depot locations and their corresponding capacities is considered. A two-stage mixed integer programming approach for rolling stock scheduling with maintenance requirements is extended to account for depot selection. First, a conventional flow-based model is solved, ignoring maintenance requirements, to obtain a variety of rolling stock schedules with multiple depot locations and capacity options. Then, a maintenance feasible rolling stock schedule can be obtained by solving a series of assignment problems by using the schedules found in the first stage. The proposed methodology is tested on real-life instances, and the numerical experiments of different operational scenarios are discussed.
Removal of dead fish eggs by Asellus aquaticus as a potential biological control in aquaculture
Authors: Kucska Balázs , Ngọc Quyến Nguyễn , Ivánovics Bence , Staszny Ádám , Havasi Máté , Vranovics Károly , Griffitts Jeffrey Daniel , Varga Ádám , Urbányi Béla , Müller Tamás 
Published: March 2024

AbstractThe objective of the present experimental study was to gain a better understanding of the foraging activity of Asellus aquaticus during fish egg incubation. A. aquaticus were introduced into experimental setups of dead eggs, viable eggs and hatched larvae of zebrafish (Danio rerio), a commonly used model organism. The amount of A. aquaticus and the duration of their exposure to the eggs significantly affected the proportion of consumed dead eggs in each experimental cycle. A. aquaticus belongs to the group of aquatic detritivores, and no predatory behavior was observed during the experiments. These crustaceans could distinguish between the dead eggs and those containing living embryos. Furthermore, zebrafish larvae remained unharmed by A. aquaticus, even in the absence of alternative food source. These findings underscore the potential sanitary role of these crustaceans in natural waters and offer new perspectives on their possible use as biological control organisms in aquaculture hatcheries. Additionally, our results suggest a potential application of A. aquaticus in combating pathogens by reducing the growth substrates for bacteria and fungi.
Effects of psychological stress on the emission of volatile organic compounds from the skin
Authors: Lucchi Géraldine , Crépin Marine , Chambaron Stéphanie , Peltier Caroline , Gilbert Laura , Guéré Christelle , Vié Katell 
Published: March 2024

AbstractThirty-five women were included in a clinical study to characterize the volatile organic compounds (VOCs) emitted by the skin during exposure to psychological stress. An original silicon-based polymeric phase was used for VOC sampling on the forehead before and after stress induction. Cognitive stress was induced using specialized software that included a chronometer for semantic and arithmetic tasks. Assessment of stress was monitored using a State-trait anxiety inventory questionnaire, analysis of participants’ verbal expressions and clinical measurements. Identification and relative quantification of VOCs were performed by gas chromatography-mass spectrometry. Stress induction was validated by a significant increase in state-anxiety as indicated by the questionnaire, modifications in electrodermal activity measurements and the expression of stress verbatims. In parallel, a sebum production increase and a skin pH decrease were observed. A total of 198 VOCs with different potential sources were identified. They were categorized in 5 groups: probable cosmetic composition, VOCs produced by the body or its microbiota, environmental origin, and dietary intake. In our qualitative statistical approach, three VOCs were found to be correlated with stress induction and 14 compounds showed significance in the paired Wilcoxon test. Fatty-acyls derived from lipids were predominantly identified as well as ethylbenzenes.
Research on inhibitory effect of mixed suppressants CaCO3, KCl, and K2CO3 on coal dust explosion pressure
Authors: Liu Tianqi , Liu Kenan 
Published: March 2024

AbstractTo discuss the inhibitory effect of micrometer scale coal dust explosion pressure, three types of explosion suppressants are selected for mixed explosion suppression. The results indicate that the coal dust explosion process includes three stages: accelerated and decelerated energy release, as well as energy dissipation. When using explosive suppressants, K2CO3 has the greatest inhibitory effect on coal dust explosion, followed by KCl, and CaCO3 has the smallest effect. The K2O, K2O2, and KOH generated by the thermal decomposition of K2CO3 can also block the heat transfer of coal dust, playing a good role in suppressing explosions. The explosion suppression effect of mixing CaCO3 and K2CO3 is better than that of mixing CaCO3 and KCl, and is worse than the explosion suppression effect of using K2CO3 alone. The synergistic effect of KCl and K2CO3 mixed explosion suppression makes the suppression effect better than using K2CO3 alone. This is because KCl generates K2O during pyrolysis, promoting the dynamic equilibrium of K2CO3 explosion suppression process. This makes mixed explosion suppression more worthy of attention and adoption when considering purchase costs.
Validating the Use of Percent Grammatical Utterances for Assessing Mandarin-Speaking Children's Grammatical Skill: Evidence From 3-Year-Olds
Authors: Guo Ling-Yu , Lee Ping , Hsu Hsin-jen , Spencer Linda 
Published: March 2024

Purpose:
The study examined the use of percent grammatical utterances (PGUs) for assessing grammatical skills in Mandarin-speaking 3-year-old children.

Method:
Participants were 30 Mandarin-speaking 3-year-olds with typical development. Language samples were collected in two visits for each child using a picture description task. Children were asked to talk about 16 pictures in response to questions and prompts at each visit. Pictures for the language sample collection were identical across the visits. PGUs were computed, and the grammatical errors that children produced in the task were coded and tallied for error types at each visit. Test–retest reliability, split-half reliability, and concurrent criterion validity of PGUs were evaluated.

Results:

The mean PGU level was approximately 78% at Visit 1 and 81% at Visit 2, both of which were significantly below the mastery level (i.e., 90%). The correlation coefficient for test–retest reliability of PGU was large (
r
= .70,
p
< .01); the correlation coefficient for split-half reliability was medium at Visit 1 (
r
= .47,
p
< .01) and large (
r
= .65,
p
< .01) at Visit 2. In addition, the correlation coefficient for concurrent criterion validity of PGU was medium for both visits (
r
s ≥ .35,
p
s ≤ .03). The ranking and proportion of each error type were similar between the visits.

Conclusion:
The initial evidence from psychometric properties suggests that PGU computed from the picture description task is a reliable and valid measure for evaluating grammatical skills in Mandarin-speaking 3-year-old children.

Supplemental Material:

https://doi.org/10.23641/asha.25395499
Robust flux angle control of induction motors to improve efficiency at light loads
Authors: Mohebbi Mohammad Reza , Arab Khaburi Davood 
Published: March 2024

AbstractVector control of induction motors has provided us with both good performance and acceptable efficiency at rated loads. Using this method at light loads reduces the efficiency due to the adjustment of motor flux at the rated value. Electric motors are normally used even at lower loads than the rated ones and often selected oversized. Enhancing the efficiency of induction motors at light loads will significantly reduce electric energy consumption. A novel method called Flux Angle Control (FAC) of the induction motor is presented to improve efficiency in the steady state at light loads. To increase the accuracy of the induction motor model we consider iron losses. This method controls the angle between the stator flux (stator current) and the d‐axis (rotor flux direction). The primary aim of the flux angle control method is to reduce the flux level and increase the flux angle at light loads. The optimal flux angle is sensitive to some induction motor parameters. The proposed method offers several advantages compared to similar methods, including high efficiency, minimal sensitivity of the optimal flux angle to changes in motor parameters, a reduced number of calculations, and easy implementation. The validity of this method is examined through experiments.