bluuebunny/crossref_metadata_2025_split huggingface dataset:
Acardiac fetus: Evidence in support of a vascular/hypoxia pathogenesis for isolated oral clefting
Authors: Jones Kenneth Lyons , Webster William S. , Vaux Keith K. , Benirschke Kurt 
Published: June 2008

AbstractBACKGROUND:The acardiac human fetus represents an accident of monozygotic twinning or higher multiple births due to an artery‐to‐artery and a vein‐to‐vein anastomosis in the monochorial placenta. Blood returning to the placenta through the umbilical artery of a normal cotwin is directed into the umbilical artery of the acardiac twin such that blood reaching the cranial end of the embryo is likely to be poorly oxygenated resulting in a number of structural defects including oral clefts. Although retrograde perfusion as a cause of hypoxia is unique to the acardiac fetus, there is ample evidence from animal studies that hypoxia is associated with facial clefting.METHODS:Twenty‐six acardiac fetuses were examined at UCSD Medical Center between 1974 and 2003.RESULTS:In 12 of the 26, the cephalic end of the fetus was sufficiently intact to document the structures of the face. Of these, cleft lip ± palate was present in five and cleft palate alone was present in one. In all six, the oral cleft followed the normal planes of facial closure. The cotwin in all six cases was normal.CONCLUSIONS:This article suggests that decreased blood flow/hypoxia to the cephalic end of the fetus may be an important contributor to the development of cleft lip ± palate and cleft palate alone in the acardiac fetus and raises the possibility that this may also be a mechanism responsible for oral clefting in singletons. Birth Defects Research (Part A) 2008. © 2008 Wiley‐Liss, Inc.
Nicotinamide N‐methyl transferase (NNMT) gene polymorphisms and risk for spina bifida
Authors: Lu Wei , Zhu Huiping , Wen Shu , Yang Wei , Shaw Gary M. , Lammer Edward J. , Finnell Richard H. 
Published: June 2008

AbstractBACKGROUND:Moderate hyperhomocysteinemia is a known risk factor for NTDs in a variety of experimental model systems and is believed to be important in humans as well. The enzyme nicotinamide N‐methyl transferase (NNMT) was identified in a genome‐wide linkage scan as being an important regulator of homocysteine homeostasis in a Spanish population, making it an interesting candidate gene for NTDs.METHODS:We evaluated 11 SNPs (single nucleotide polymorphism) of the NNMT gene in our study population. In this study, 252 cases (infants with spina bifida) and 335 controls (nonmalformed infants), born during the period 1983–1986 in selected counties in California, were genotyped for variants of the NNMT gene. Allelic, genotype, and haplotype associations with spina bifida risk were evaluated and analyzed.RESULTS:None of the SNPs studied alone showed allelic or genotypic associations with spina bifida. However, the TCAG haplotype for block 3 (rs2852447, ra2852425, rs4646337, and rs11569688) showed a decreased risk for spina bifida among non‐Hispanic Whites (OR 0.4; 95%CI: 0.1–1.0).CONCLUSIONS:No association was found between infant NNMT gene variants and risk for spina bifida in our study population. However, small sample sizes for most variant groups and for phase‐unknown haplotype data limited the power of the study. Birth Defects Research (Part A) 2008. © 2008 Wiley‐Liss, Inc.
Possible association between acute pelvic inflammatory disease in pregnant women and congenital abnormalities in their offspring: A population‐based case‐control study
Authors: Ács Nándor , Bánhidy Ferenc , Puhó Erzsébet H. , Czeizel Andrew E. 
Published: June 2008

AbstractBACKGROUND:The possible association between acute pelvic inflammatory diseases (APID) of pregnant women and structural birth defects, that is, congenital abnormalities (CA) in their offspring, has not been studied.METHODS:The data set of the Hungarian Case‐Control Surveillance of Congenital Abnormalities, 1980 and 1996, were evaluated.RESULTS:There were 67 out of 22,843 (0.29%) cases and 128 out of 38,151 (0.34%) controls with mothers who had prospectively and medically recorded APID during the second and/or third gestational months (adjusted prevalence OR with 95% CI: 0.95, 0.70–1.29). However, of 12 CA groups evaluated, APID was associated with a higher risk only for cardiovascular CAs (adjusted prevalence OR with 95% CI: 2.6, 1.2–5.4) and the observed number of cases with atrial septal defect, type II with maternal APID exposure exceeded 4.2‐fold its expected number.CONCLUSIONS:A possible explanation for the association of APID with higher risk for cardiovascular CA is the high fever of APID, but this signal finding needs confirmation. Birth Defects Research (Part A) 2008. © 2008 Wiley‐Liss, Inc.
Preparation and anti‐tumor efficiency evaluation of doxorubicin‐loaded bacterial magnetosomes: Magnetic nanoparticles as drug carriers isolated from Magnetospirillum gryphiswaldense
Authors: Sun Jian‐Bo , Duan Jin‐Hong , Dai Shun‐Ling , Ren Jun , Guo Lin , Jiang Wei , Li Ying 
Published: June 2008

AbstractBacterial magnetosomes (BMs) are commonly used as vehicles for certain enzymes, nucleic acids and antibodies, although they have never been considered drug carriers. To evaluate the clinical potential of BMs extracted from Magnetospirillum gryphiswaldense in cancer therapy, doxorubicin (DOX) was loaded onto the purified BMs at a ratio of 0.87 ± 0.08 mg/mg using glutaraldehyde. The DOX‐coupled BMs (DBMs) and BMs exhibited uniform sizes and morphology evaluated by TEM. The diameters of DBMs and BMs obtained by AFM were 71.02 ± 6.73 and 34.93 ± 8.24 nm, respectively. The DBMs released DOX slowly into serum and maintained at least 80% stability following 48 h of incubation. In vitro cytotoxic tests showed that the DBMs were cytotoxic to HL60 and EMT‐6 cells, manifested as inhibition of cell proliferation and suppression in c‐myc expression, consistent with DOX. These observations depicted in vitro antitumor property of DBMs similar to DOX. The approach of coupling DOX to magnetosomes may have clinical potential in anti‐tumor drug delivery. Biotechnol. Bioeng. 2008;101: 1313–1320. © 2008 Wiley Periodicals, Inc.
ChemInform Abstract: Quantum Chemical Calculations on a Selection of Iodine‐Containing Species (IO, OIO, INO3, (IO)2, I2O3, I2O4 and I2O5) of Importance in the Atmosphere.
Authors: Kaltsoyannis Nikolas , Plane John M. C. 
Published: June 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Thermal Expansion Properties of A2(MO4)3 (A: Ho and Tm; M: W and Mo).
Authors: Xiao X. L. , Cheng Y. Z. , Peng J. , Wu M. M. , Chen D. F. , Hu Z. B. , Kiyanagi R. , Fieramosca J. S. , Short S. , Jorgensen J. 
Published: June 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Interstitial Oxygen in Perovskite‐Related Sr6‐2xNb2+2xO11+3x.
Authors: Li Man‐Rong , Hong Seung‐Tae 
Published: June 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: The Al—B—Nb—Ti System. Part 2. Thermodynamic Description of the Constituent Ternary System B—Nb—Ti.
Authors: Witusiewicz V. T. , Bondar A. A. , Hecht U. , Rex S. , Velikanova T. Ya. 
Published: June 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Crystal and Band Structures, and Optical Characterizations of Sodium Rare Earth Phosphates NaLnP2O7 and NaLn(PO3)4 (Ln: Ce, Eu).
Authors: Zhu Jing , Cheng Wen‐Dan , Wu Dong‐Sheng , Zhang Hao , Gong Ya‐Jing , Tong Hua‐Nan , Zhao Dan 
Published: June 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: A Nitrido‐Centered Uranium Azido Cluster Obtained from a Uranium Azide.
Authors: Nocton Gregory , Pecaut Jacques , Mazzanti Marinella 
Published: June 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Chemodivergence in Enantioselective Desymmetrization of Diazabicycles: Ring‐Opening versus Reductive Arylation.
Authors: Menard Frederic , Lautens Mark 
Published: June 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Chiral Amine‐Thioureas Bearing Multiple Hydrogen Bonding Donors: Highly Efficient Organocatalysts for Asymmetric Michael Addition of Acetylacetone to Nitroolefins.
Authors: Wang Chun‐Jiang , Zhang Zhi‐Hai , Dong Xiu‐Qin , Wu Xiao‐Jun 
Published: June 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Enamide Synthesis by Copper‐Catalyzed Cross‐Coupling of Amides and Potassium Alkenyltrifluoroborate Salts.
Authors: Bolshan Yuri , Batey Robert A. 
Published: June 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Ruthenium‐Catalyzed Vinylic Substitution Reactions with Nucleophiles via Butatrienylidene Intermediates.
Authors: Yamauchi Yoshihiro , Yuki Masahiro , Tanabe Yoshiaki , Miyake Yoshihiro , Inada Youichi , Uemura Sakae , Nishibayashi Yoshiaki 
Published: June 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Enzyme‐Like Chemoselective Acylation of Alcohols in the Presence of Amines Catalyzed by a Tetranuclear Zinc Cluster.
Authors: Ohshima Takashi , Iwasaki Takanori , Maegawa Yusuke , Yoshiyama Asako , Mashima Kazushi 
Published: June 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Rhodium‐Catalyzed Hydroarylation and Hydroalkenylation of Alkynes Using Organo[2‐(hydroxymethyl)phenyl]dimethylsilanes.
Authors: Nakao Yoshiaki , Takeda Masahide , Chen Jinshui , Hiyama Tamejiro 
Published: June 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Rh(III)‐ and Ir(III)‐Catalyzed Asymmetric Transfer Hydrogenation of Ketones in Water.
Authors: Wu Xiaofeng , Li Xiaohong , Zanotti‐Gerosa Antonio , Pettman Allan , Liu Jianke , Mills Allan James , Xiao Jianliang 
Published: June 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Palladium‐Catalyzed Carbonylation of Aryl Tosylates and Mesylates.
Authors: Munday Rachel H. , Martinelli Joseph R. , Buchwald Stephen L. 
Published: June 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Sustainable Suzuki—Miyaura Reaction Catalyzed by Pd(OAc)2 Immobilized on Reversed‐Phase Alumina.
Authors: Hagiwara Hisahiro , Ko Keon Hyeok , Hoshi Takashi , Suzuki Toshio 
Published: June 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: One‐Step Synthesis of Polysubstituted Benzene Derivatives by Multicomponent Cyclization of α‐Bromoacetate, Malononitrile and Aromatic Aldehydes.
Authors: Yan Chao Guo , Song Xiao Kai , Wang Qi Fang , Sun Jing , Siemeling Ulrich , Bruhn Clemens 
Published: June 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Ring Selectivity: Successive Ring Expansion of Two Benzocyclobutenes for Divergent Access to Angular and Linear Benzanthraquinones.
Authors: Suzuki Takeaki , Hamura Toshiyuki , Suzuki Keisuke 
Published: June 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Gold(I)‐Catalyzed Intramolecular Hydroarylation of Allenes.
Authors: Tarselli Michael A. , Gagne Michel R. 
Published: June 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Highly Stereoselective Synthesis of Substituted γ‐Lactams from Acylsilanes.
Authors: Lettan Robert B. II , Woodward Chase C. , Scheidt Karl A. 
Published: June 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Efficient Synthesis of 2,6‐Dioxo‐1,2,3,4,5,6‐hexahydroindoles Based on the Synthesis and Reactions of (2,4‐Dioxocyclohex‐1‐yl)acetic Acid Derivatives.
Authors: Juma Benard , Adeel Muhammad , Villinger Alexander , Langer Peter 
Published: June 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Microwave‐Promoted Oxidation of 1,3,5‐Trisubstituted 4,5‐Dihydro‐1H‐pyrazoles by in situ Generation of NO+ and NO2+ Respectively from Sodium Nitrite and Sodium Nitrate in Acetic Acid.
Authors: Azarifar Davood , Maleki Behrooz , Sahraei Mahta 
Published: June 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Direct Amination of Homoenolates Catalyzed by N‐Heterocyclic Carbenes.
Authors: Chan Audrey , Scheidt Karl A. 
Published: June 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: An Efficient and One‐Pot Synthesis of 2,4,5‐Trisubstituted and 1,2,4,5‐Tetrasubstituted Imidazoles Catalyzed by InCl3×3H2O.
Authors: Das Sharma Saikat , Hazarika Parasa , Konwar Dilip 
Published: June 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: A Facile Synthesis of 5(6)‐(Chloromethyl)benzimidazoles: Replacement of a Sulfonic Acid Functionality by Chlorine.
Authors: Pete Bela , Szokol Balint , Toeke Laszlo 
Published: June 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Simple and Efficient One‐Pot Synthesis of 3,4‐Dihydro‐2‐pyridones via Solid‐Supported Bi(III)nitrate‐Catalyzed Double Michael Addition—Azaannulation.
Authors: Singh Jagjeet , Koul Summon , Pannu Ajay P. S. , Sharma Rattan L. , Razdan Tej K. 
Published: June 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Microwave‐Assisted Doebner Synthesis of 2‐Phenylquinoline‐4‐carboxylic Acids and Their Antiparasitic Activities.
Authors: Muscia Gisela C. , Carnevale Juan P. , Bollini Mariela , Asis Silvia E. 
Published: June 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis and Characterization of a Novel Heterocycle: 1‐Substituted‐4‐arylazamethylene‐6‐arylpyrazolo[5,4‐d]‐1,3‐oxazine.
Authors: He Kunlun , Lv Houjun , Wang Junbo , Qiu Guofu , Hu Xianming 
Published: June 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Rh‐Catalyzed Carbonyl Hydroacylation: An Enantioselective Approach to Lactones.
Authors: Shen Zengming , Khan Hasan A. , Dong Vy M. 
Published: June 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Two New Cycloartane Saponins from the Roots of Astragalus membranaceus
Authors: Kim Ju Sun , Yean Min‐Hye , Lee Eun‐Ju , Jung Hye Sil , Lee Joo Young , Kim Yoon Jung , Kang Sam Sik 
Published: June 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Total Syntheses of Bistratamides J, E, and H from Two Types of ΔAla‐Containing Oligopeptides.
Authors: Suzuki Hiroyuki , Andoh Masanori , Yonezawa Yasuchika , Akai Shoji , Shin Chung‐gi , Sato Ken‐ichi 
Published: June 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis and Characterization of Novel Azo‐Morphine Derivatives for Possible Use in Abused Drugs Analysis.
Authors: Alnajjar Ahmed O. , El‐Zaria Mohamed E. 
Published: June 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Unsaturated Fluoro‐ketopyranosyl Nucleosides: Synthesis and Biological Evaluation of 3‐Fluoro‐4‐keto‐β‐D‐glucopyranosyl Derivatives of N4‐Benzoyl Cytosine and N6‐Benzoyl Adenine.
Authors: Manta Stella , Agelis George , Botic Tanja , Cencic Avrelija , Komiotis Dimitri 
Published: June 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Flexophore, a New Versatile 3D Pharmacophore Descriptor that Considers Molecular Flexibility.
Authors: von Korff Modest , Freyss Joel , Sander Thomas 
Published: June 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.