bluuebunny/crossref_metadata_2025_split huggingface dataset:
A novel rotary ultrasonic motor based on multiple Langevin transducers: design, simulation, and experimental investigation
Authors: Ma Xinchi , Yang Ying , Qiu Jianmin , Zhang Jiyang , Vasiljev Piotr , Wu Jintao , Mazeika Dalius , Zhao Lei , Borodinas Sergejus , Liu Jikui 
Published: March 2024

Abstract
Traveling wave rotary ultrasonic motors (TRUSMs) have been applied in optical systems, robotics, biomedical and other fields. However, the disadvantages such as short working life, driving performance degradation, and low energy utilization significantly limit the long-term and stable operation of TRUSMs in advanced fields like aerospace mechanisms. To address the above issues, a novel rotary ultrasonic motor based on multiple Langevin transducers is proposed in this paper. First, the structural design, driving principle and general design criteria are described in detail. Then, the structural parameters are optimized by finite element simulation analysis. Second, a prototype is assembled controllably. Subsequently, the impedance test and vibration measurement are carried out. The results show that the traveling wave is successfully generated on the tooth-ring, and all the Langevin transducers are excited to the first-order longitudinal vibration modes, which strongly verify the correctness of design principle. Finally, the driving performance experiment is carried out. The experimental results show that the no-load speed is 62 r min−1 under the pre-pressure of 10 N. The stalling torque is 0.94 N m at the driving voltage of 500 Vp-p. The response characteristics show that the start/stop time are 4.6/5.5 ms, and the angular displacement resolution of clockwise/counterclockwise driving are 6.7/10.2 μrad. The motor proposed in this paper not only exhibits relatively high output performance with excellent vibration characteristics, but also maintains compactness of the structure. The sandwiched structure design effectively avoids the problem that the bonded-type piezoceramic rings in conventional TRUSMs are prone to damage or fall-off when vibrating for a long time. Furthermore, the general design criteria provide a new approach to develop high performance rotary ultrasonic motors. The proposed novel ultrasonic motor is expected to meet the demand for long-term and stable operation in aerospace mechanisms.
Muscle-inspired stiffness-tunable flexible fiber jamming structure for wearable robots
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Authors: Ma Junlin , Chen Diansheng , Liu Zhe , Li Jialing , Zeng Zihan , Yin Yingxitong , Zhang Xianglin , Shu Chen , Zhu Yaohui , Fu Zhihan , Jiang Yongkang 
Published: March 2024

Abstract
Soft robotics have found their tremendous application prospects in wearable robots due to the inherent compliance of soft materials when interacting with human bodies. However, the limited load-bearing and output capabilities impeded their application in real world. Variable stiffness design contributes to tackling this problem by enhancing the overall structural rigidity. Nevertheless, most of current jamming-based variable stiffness structures realize their stiffness enhancement by squeezing discrete rigid elements, resulting in the loss of structural compliance in the high stiffness state, which could significantly reduce the deformability and even injure the individuals when utilized in wearable robots. In this paper, we propose a muscle-inspired stiffness-continuously-adjustable flexible fiber jamming (FFJ) structure for soft wearable robots. The FFJ structure can achieve continuous stiffness-variation by controlling the fiber overlapping length, which maintains stretchability even in the high stiffness state. We provide a theoretical model to analyze the mechanical performance of the proposed FFJ structure with different design parameters, and verify the model experimentally. The preliminary results show that we achieved 9 times of stiffness enhancement of the proposed FFJ structure by controlling the vacuum pressure, and the maximum tensile stiffness is 4.1 N mm−1. We further demonstrated the effectiveness of the proposed FFJ structure on wearable robots in three different working scenarios: active finger rehabilitation, active elbow rehabilitation, and passive trunk support. The results show that the FFJ structure was able to provide controllable impedance force for active finger/elbow rehabilitation, and help support the human body during long-term labor. This work broadens the frontiers of soft wearable robots and leads a way to the future design of soft and strong robots and devices.
A new ER valve composed of multilayer mesh electrodes
Authors: Xu Luning , Zhang Jiahui , Huang Jingyu , Han Li , Shen Rong , Lu Kunquan 
Published: March 2024

Abstract
In many cases, ER valves are required to be used at lower operating voltages. For example, to develop a two-dimensional Braille matrix display, it is necessary to lay out many ER valves and control each Braille dot independently. If the commonly used parallel plate electrodes are applied, a low voltage can only be used when the electrode gap is very small, which will make the ER valve flow resistance very large, thus making it difficult to achieve effective control. A new type of ER valve composed of multilayer mesh electrodes was designed, which are arranged vertically in the direction of ER fluid flow. The flow rate of the ER valve is determined by the opening ratio of the mesh electrodes. This type of mesh electrode results in a more complex electric field distribution, which has a different action pattern on ER fluid yield stress compared to parallel electrodes. The non-uniform electric field generated by mesh electrodes under different operating voltages was simulated using COMSOL software, and the pressure drops of ER valves with various sizes of mesh electrodes under different voltages were experimentally investigated. The results indicate that the longitudinal electric field component plays a dominant role, and the stress of the ER fluid exhibits a periodic and gradient distribution. This valve exhibits good ER performance when the applied voltage is much lower than that of parallel electrodes. At the same time, the flow rate of the ER valve can be increased by enlarging the opening ratio of the mesh electrodes. Even if the applied voltage is 180 V, the pressure drop of the ER valve is large enough and the operation stability is good. This new type of ER valve makes the device small in size, easy to control intelligently and low cost. Multilayer mesh electrodes also have universal application value in ER technology.
Dissociating reading and auditory comprehension in persons with aphasia
Authors: Harrington Rachael M , Kristinsson Sigfus , Wilmskoetter Janina , Busby Natalie , den Ouden Dirk , Rorden Chris , Fridriksson Julius , Bonilha Leonardo 
Published: March 2024

Abstract
Language comprehension is often affected in individuals with post-stroke aphasia. However, deficits in auditory comprehension are not fully correlated with deficits in reading comprehension and the mechanisms underlying this dissociation remain unclear. This distinction is important for understanding language mechanisms, predicting long-term impairments and future development of treatment interventions. Using comprehensive auditory and reading measures from a large cohort of individuals with aphasia, we evaluated the relationship between aphasia type and reading comprehension impairments, the relationship between auditory versus reading comprehension deficits and the crucial neuroanatomy supporting the dissociation between post-stroke reading and auditory deficits. Scores from the Western Aphasia Battery—Revised from 70 participants with aphasia after a left-hemisphere stroke were utilized to evaluate both reading and auditory comprehension of linguistically equivalent stimuli. Repeated-measures and univariate ANOVA were used to assess the relationship between auditory comprehension and aphasia types and correlations were employed to test the relationship between reading and auditory comprehension deficits. Lesion-symptom mapping was used to determine the dissociation of crucial brain structures supporting reading comprehension deficits controlling for auditory deficits and vice versa. Participants with Broca’s or global aphasia had the worst performance on reading comprehension. Auditory comprehension explained 26% of the variance in reading comprehension for sentence completion and 44% for following sequential commands. Controlling for auditory comprehension, worse reading comprehension performance was independently associated with damage to the inferior temporal gyrus, fusiform gyrus, posterior inferior temporal gyrus, inferior occipital gyrus, lingual gyrus and posterior thalamic radiation. Auditory and reading comprehension are only partly correlated in aphasia. Reading is an integral part of daily life and directly associated with quality of life and functional outcomes. This study demonstrated that reading performance is directly related to lesioned areas in the boundaries between visual association regions and ventral stream language areas. This behavioural and neuroanatomical dissociation provides information about the neurobiology of language and mechanisms for potential future treatment interventions.
Stereoselective synthesis of multi-functionalized chiral silacyclopentanes
Authors: Kuroo Akihiro , Igawa Kazunobu , Tomooka Katsuhiko 
Published: March 2024

Abstract
We have synthesized multifunctionalized silacyclopentanes in a highly selective manner from enantioenriched silacyclopentenol, which is readily accessible from achiral silacyclopentene oxide by enantioselective β-elimination. Functionalization at C2, C4, and C5 positions of silacyclopentenol was achieved based on the regio- and stereoselective nucleophilic substitution reaction of epoxides.
Treatment of Multidrug-resistant or Rifampicin-resistant Tuberculosis With an All-oral 9-month Regimen Containing Linezolid or Ethionamide in South Africa: A Retrospective Cohort Study
Authors: Morgan Hannah , Ndjeka Norbert , Hasan Tasnim , Gegia Medea , Mirzayev Fuad , Nguyen Linh N , Schumacher Samuel , Schlub Timothy E , Naidoo Kogieleum , Fox Greg J 
Published: March 2024

Abstract

Background
In 2019, the South African tuberculosis program replaced ethionamide with linezolid as part of an all-oral 9-month regimen. We evaluated treatment outcomes for patients assigned to regimens including linezolid in 2019 and ethionamide in 2017.

Methods
This retrospective cohort study included patients treated for multidrug-resistant/rifampicin-resistant tuberculosis throughout South Africa between 1 January and 31 December 2017 and 1 January to 31 December 2019. The cohort treated with a 9-month regimen containing ethionamide for four months, was compared with a cohort treated with a 9-month regimen containing linezolid for 2 months. The regimens were otherwise identical. Inverse probability weighting of propensity scores was used to adjust for potential confounding. A log-binomial regression model was used to estimate adjusted relative risk (aRR) comparing 24-month outcomes between cohorts including treatment success, death, loss to follow up, and treatment failure. Adverse event data were available for the linezolid cohort.

Findings
In total, 817 patients were included in the cohort receiving ethionamide and 4244 in the cohort receiving linezolid. No evidence for a difference was observed between linezolid and ethionamide regimens for treatment success (aRR = 0.96, 95% confidence interval [CI] .91–1.01), death (aRR = 1.01, 95% CI .87–1.17) or treatment failure (aRR = 0.87, 95% CI .44–1.75). Loss to follow-up was more common in the linezolid group, although estimates were imprecise (aRR = 1.22, 95% CI .99–1.50).

Conclusions
No significant differences in treatment success and survival were observed with substitution of linezolid for ethionamide as a part of an all-oral 9-month regimen. Linezolid is an acceptable alternative to ethionamide in this shorter regimen for treatment of multidrug-resistant/rifampicin-resistant tuberculosis.
Eosinophilic esophagitis prevalence, incidence, and presenting features: a 22-year population-based observational study from southwest Sweden
Authors: Plate J , Söderbergh T , Bergqvist J , Lingblom C , Bergquist H , Larsson H 
Published: March 2024

Summary
Eosinophilic esophagitis (EoE) is a chronic inflammatory condition of the esophagus that affects both children and adults. Symptoms in adults are mainly esophageal dysphagia, which ranges from mild symptoms to acute food bolus obstruction of the esophagus. Diagnosis is defined as symptoms of esophageal dysfunction and ≥ 15 eosinophils/high power field (HPF) in at least one of the biopsies taken from the esophagus. EoE appears to be increasing in both prevalence and incidence. The aim of this study was to investigate the prevalence, incidence, and presenting symptoms of patients with EoE within the catchment area of Northern Älvsborg County Hospital in Trollhättan. Patient records with the ICD code of EoE between 2012 and 2022 and pathology reports from esophageal biopsies from 2000–2022 were examined. Patients with symptoms of esophageal dysfunction and &gt; 15 eosinophils/HPF were classified as having EoE. In total, 409 EoE patients (379 adults and 30 children) fulfilled the diagnostic criteria during the follow-up period. The overall prevalence was 113 cases/100 000 inhabitants (adults 127/100 000 and children 57/100 000) at 31 December 2022. The incidence was 7/100 000 and increased during the observation period. At diagnosis, 46% of the adults and 11% of the children had a history of acute bolus obstruction requiring hospitalization, while 51% of adults and 22% of children exhibited endoscopic findings of fibrosis. The prevalence of EoE is significantly higher than that generally reported in an area of southwest Sweden. The results indicate that the incidence is increasing; however, whether this is due to an actual increase or heightened awareness of EoE is inconclusive. Acute bolus obstruction is a common presenting symptom among EoE patients and is most likely an effect of late diagnosis.
Frailty in the cardiac intensive care unit: assessment and impact
Authors: Moumneh Mohamad B , Jamil Yasser , Kalra Kriti , Ijaz Naila , Campbell Greta , Kochar Ajar , Nanna Michael G , van Diepen Sean , Damluji Abdulla A 
Published: March 2024

Abstract
Frailty, a clinical syndrome of increased vulnerability, due to diminished cognitive, physical, and physiological reserves is a growing concern in the cardiac intensive care unit (CICU). It contributes to morbidity, mortality, and complications and often exerts a bidirectional association with cardiovascular disease. Although it predominately affects older adults, frailty can also be observed in younger patients &lt;65 years of age, with approximately 30% of those admitted in CICU are frail. Acute cardiovascular illness can also impair physical and cognitive functioning among survivors and these survivors often suffer from frailty and functional declines post-CICU discharge. Patients with frailty in the CICU often have higher comorbidity burden, and they are less likely to receive optimal therapy for their acute cardiovascular conditions. Given the significance of this geriatric syndrome, this review will focus on assessment, clinical outcomes, and interventions, in an attempt to establish appropriate assessment, management, and resource utilization in frail patients during and after CICU admission.
Introduction to the special issue: evolutionary and biopsychosocial perspectives on sickness communication
Authors: Shattuck Eric C , Boyle Chloe C 
Published: March 2024

Abstract
Here, we introduce the EMPH special issue on Evolutionary and Biopsychosocial Perspectives on Sickness Communication. This Commentary provides an overview of each article and places them in the wider context of sickness as a social phenomenon with verbal and nonverbal signals. This Commentary, and the special issue, in general, calls for greater attention to these signals that can affect pathogen transmission and may be at the evolutionary root of our caregiving systems and behaviours.
Succeeding without belonging? A double comparison of migrants’ socio-economic attainment and national belonging across origin and residence countries
Authors: Geurts Nella , Phalet Karen 
Published: March 2024

Abstract
When is migrants’ socio-economic attainment associated with enhanced national belonging to their residence country? Drawing on a large-scale survey, we compare migrants from the same 10 origin countries across Denmark, Germany, and the Netherlands. We exploit this double comparison across origin groups and residence countries to contextualize mixed findings of positive, negative, and null associations between migrants’ socio-economic attainment and national belonging in earlier research. We introduce the notion of ethnic boundaries to situate when migrants’ socio-economic attainment and belonging are positively or negatively associated. We examine how migrants’ socio-economic attainment interacts with contextual variation in ethnic boundaries and with individual-level variation in perceptions of ethnic boundaries based on perceived group discrimination. Multi-group structural equation models show that migrants’ socio-economic attainment is often decoupled from national belonging. However, they also reveal crucial contextual variation as same-origin migrants can succeed socio-economically with or without feeling belonging in different residence countries. At the individual level, perceived group discrimination conditions this association, so that socio-economic attainment translates into more national belonging only when perceptions of discrimination are low. Our comparative findings of contingent national belonging thereby challenge existing assumptions that associations between socio-economic attainment and national belonging are linear and that ethnic boundaries in European migration contexts are rigid.
The relationship between processed meat, red meat, and risk of cardiovascular disease and Type 2 diabetes: a Mendelian randomization study
Authors: Li Guangling , Jiang Jiangang , Li Zeping 
Published: March 2024

Abstract

Aims
Numerous observational studies have indicated a potential association between the consumption of processed and red meat and an increased risk of cardiovascular disease and Type 2 diabetes mellitus (T2DM). However, the presence of a causal relationship remains uncertain. Therefore, the purpose of this study was to evaluate the impact of processed meat and red meat (pork, lamb, and beef) on the risk of cardiovascular disease, including coronary artery disease (CAD), hypertension, and stroke, and T2DM, using a two-sample Mendelian randomization (MR) analysis.

Methods and results
An MR analysis was conducted using the inverse-variance weighted, weighted median, and MR-Egger methods. To identify heterogeneity and pleiotropy, Cochrane’s Q test and MR-Egger test were employed. Additionally, the stability of the MR results was assessed using the leave-one-out method. Inverse-variance weighted analyses reveal no causal association between the consumption of processed and red meat and the incidence of CAD, hypertension, stroke, and T2DM (P &gt; 0.05). When considering processed meat intake, heterogeneity is observed in hypertension and stroke outcomes (P &lt; 0.05). For pork intake, heterogeneity is seen in hypertension, stroke, and T2DM (P &lt; 0.05). Lamb intake shows heterogeneity in hypertension and T2DM (P &lt; 0.05). However, other exposures and outcomes examined show no heterogeneity (P &gt; 0.05). No significant pleiotropy is detected for all exposures through an MR-Egger test (P &gt; 0.05). Furthermore, the leave-one-out test demonstrates the robustness of the results.

Conclusion
The study discerned no observable impact of red and processed meat consumption on CAD, hypertension, stroke, and T2DM. The findings of this study challenge the prevailing conventional perspective in the field.
Continuous stellate ganglion block for ventricular arrhythmias: case series, systematic review, and differences from thoracic epidural anaesthesia
Authors: Dusi Veronica , Angelini Filippo , Baldi Enrico , Toscano Antonio , Gravinese Carol , Frea Simone , Compagnoni Sara , Morena Arianna , Saglietto Andrea , Balzani Eleonora , Giunta Matteo , Costamagna Andrea , Rinaldi Mauro , Trompeo Anna Chiara , Rordorf Roberto , Anselmino Matteo , Savastano Simone , De Ferrari Gaetano Maria 
Published: March 2024

Abstract

Aims
Percutaneous stellate ganglion block (PSGB) through single-bolus injection and thoracic epidural anaesthesia (TEA) have been proposed for the acute management of refractory ventricular arrhythmias (VAs). However, data on continuous PSGB (C-PSGB) are scant. The aim of this study is to report our dual-centre experience with C-PSGB and to perform a systematic review on C-PSGB and TEA.

Methods and results
Consecutive patients receiving C-PSGB at two centres were enrolled. The systematic literature review follows the latest Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) criteria. Our case series (26 patients, 88% male, 60 ± 16 years, all with advanced structural heart disease, left ventricular ejection fraction 23 ± 11%, 32 C-PSGBs performed, with a median duration of 3 days) shows that C-PSGB is feasible and safe and leads to complete VAs suppression in 59% and to overall clinical benefit in 94% of cases. Overall, 61 patients received 68 C-PSGBs and 22 TEA, with complete VA suppression in 63% of C-PSGBs (61% of patients). Most TEA procedures (55%) were performed on intubated patients, as opposed to 28% of C-PSGBs (P = 0.02); 63% of cases were on full anticoagulation at C-PSGB, none at TEA (P &lt; 0.001). Ropivacaine and lidocaine were the most used drugs for C-PSGB, and the available data support a starting dose of 12 and 100 mg/h, respectively. No major complications occurred, yet TEA discontinuation rate due to side effects was higher than C-PSGB (18 vs. 1%, P = 0.01).

Conclusion
Continuous PSGB seems feasible, safe, and effective for the acute management of refractory VAs. The antiarrhythmic effect may be accomplished with less concerns for concomitant anticoagulation compared with TEA and with a lower side-effect related discontinuation rate.