bluuebunny/crossref_metadata_2025_split huggingface dataset:
Radiation changes in vaginal and cervical cytology in carcinoma of the cervix uteri
Authors: Gupta Saroj , Gupta Y. N. , Sanyal B. 
Published: February 2007

AbstractRadiation changes are observed in all postirradiated smears of squamous cell carcinoma of the cervix from 56 females, although to a variable degree. After 1 year the changes subside gradually. A high cornification index is a good guide for recurrence. The significance of dysplastic cells as premonition for recurrence is debatable. The presence of malignant cells at any stage was considered of grave significance, and indicates poor radiation response or recurrence.
Attempts to bypass the need for splenectomy in splenic injury
Authors: Derisi D. , Petrelli N. S. , Cohen H. , Williams P. , Ambrus J. L. 
Published: February 2007

AbstractWithin the last decade spleen salvage has been a controversial issue. Only recently, with the advances and utilization of modern technology in surgery, spurred by a better understanding of this immunologically important organ, preservation has become a reality. Numerous approaches have been suggested. Reported is a simple method of applying a new agent, Fibrin Seal (FS), to control hemorrhage from splenic injury. In a controlled study using 14 mongrel dogs, it is compared to the hemostatic ability of cryoprecipitate with thrombin and Avitene. FS is an adhesive material with hemostatic qualities consisting of fibrinogen, factor XIII, antiplasmin, cold‐insoluble globulin, and platelet growth factor. FS appears to have cohesive and adhesive properties that result in more efficient hemostasis than the controls. FS conforms to the spleen surface, allowing manipulation of the organ without dislodgement of the coagulum. Follow‐up laparotomy showed minimal tissue reaction. On the basis of these data, consideration of FS as an important hemostatic agent warrants clinical investigation.
Benign glandular elements and decidual reaction in retroperitoneal lymph nodes
Authors: Yoonessi Mahmood , Satchindanand Sateesh K. , Ortinez Cesar G. , Goodell Thomas 
Published: February 2007

AbstractAmong 70 patients with gynecologic malignancies who underwent surgical staging and pelvic and periaortic lymphadenectomy, five were found to have benign glandular and/or stromal elements in the retroperitoneal lymph nodes. In three instances, these were originally diagnosed as metastatic cancer. The literature on this subject is reviewed and its significance is discussed.
Fibroma of tendon sheath
Authors: Jablokow Victor R. , Kathuria Satinder 
Published: February 2007

AbstractThree cases of fibromas involving tendon sheath of right index finger, left ring finger, and tibial ligament in a 62‐, a 54‐, and a 30‐year‐old male patient, respectively, are described. Two cases (1 and 2) represented painless, slowly enlarging masses that limited motion of the involved digits. The third case was discovered at surgery during the repair of a tibial ligament after a motorcycle accident. Following surgical excisions, no recurrences were present 18 months and 9 months after resection. The fibromas of tendon sheath origin are distinct entities and should be separated from other lesions of tendon sheaths. Trauma should be considered as the etiology. The fibromas are benign lesions but may recur.
Gastric stomal polypoid hyperplasia: Report of four cases
Authors: Jablokow Victor R. , Aranha Gerard V. , Reyes Cesar V. 
Published: February 2007

AbstractFour cases of gastric stomal polypoid hyperplasia developing at the site of gastroenterostomy are reported. Their occurrence averages about 10 years following a Billroth II resection for peptic ulcer disease. The lesions may manifest clinically as tumor masses with gastric obstruction. Whether they represent an intermediate condition between gastroenterostomy and stomal cancer is conjectural.
Malignant schwannoma of the vagus nerve: A case report and review of the literature
Authors: Rao Prakashchandra M. , Madden Robert E. , Cortes Luis E. , Rosenstock Arthur 
Published: February 2007

AbstractA case of neuroectodermal tumor, a malignant schwannoma, of the cervical vagus nerve is presented. It had been previously misdiagnosed and was a recurrence. A review of the literature reveals this to be the sixth such case reported. The difficulties in establishing a diagnosis and the principals of adequate therapy are discussed; these include wide surgical resection and postoperative radiotherapy to the tumor bed. The correct recognition of their malignant potential is essential for long‐term disease‐free survival.
Malignant melanoma with unknown primary site
Authors: Lopez R. , Holyoke E. D. , Moore R. H. , Karakousis C. P. 
Published: February 2007

AbstractFrom 1955 to 1976, 129 patients were seen with metastatic malignant melanoma from an unknown primary site, comprising 8.1% of all the referred patients with malignant melanoma. Eighty‐two percent of the patients presented with a history of mass or lump.Overall median survival and 5‐year survival rates after onset of symptoms were 10 months and 13%, respectively. Patients with lesions of the head and neck area had 5‐year disease‐free survival of 25%, whereas those with lymph node disease had a survival of 18%. Twenty‐nine patients with regional disease had wide excision (usually lymphadenectomy) and their 5‐year disease‐free survival was 58%.Regional disease in patients with malignant melanoma of unknown primary site should be treated with radical surgical excision, since the survival is comparable or better to that of patients with regional disease having known and excised primary site.
Association between primary hyperparathyroidism and previous irradiation
Authors: Tamura Kazuo , Shimaoka Katsutaro , Spaulding Stephen , Shedd Donald 
Published: February 2007

AbstractThe association between primary hyperparathyroidism and previous irradiation was investigated in two study groups. Among 36 patients with hyperparathyroidism, 4 (11%) knew of having received radiation therapy. In the second group of 323 patients with a history of radiation exposure and nodular thyroid disease, 4 (1%), thus far, were found to have hyperparathyroidism.
Metastatic cancers to the neck from undetermined primary sites long‐term follow‐up
Authors: Roseman James M. , James Arthur G. 
Published: February 2007

AbstractWhen a patient presents with a mass in the neck, diagnosis by fine needle aspiration cytology is recommended. This allows an accurate diagnosis of malignancy with minimal morbidity. Tissue planes, important in any future definite neck surgery, are not altered, as they would be from an excisional biopsy. Once the diagnosis of metastatic cancer is confirmed, thorough search for the primary tumor must be made. The history, physical examination, and radiographic and laboratory studies must be complete. Finding no origin of tumor, local treatment of the metastases must be done, with the objective being complete eradication of disease. Regular follow‐up, with a continual search for the primary malignancy is then recommended. The specifics of this approach and the results of our series are outlined.
Serum immunoglobulins in squamous cell carcinoma of the oral cavity
Authors: Khanna N. N. , Das S. N. , Khanna Sushila 
Published: February 2007

AbstractSerum immunoglobulins (IgG, IgA, and IgM) have been studied in 70 patients with squamous cell carcinoma of oral cavity and in 40 age‐matched normal controls. The results were correlated with clinical stage, tumor size, lymph node status, tumor differentiation, and treatment modalities. There was a significant rise in serum IgM and IgA in oral cancer patients as compared to controls. It was further raised in advanced clinical stage, but tumor size and histological differentiation and treatment modalities (surgery and chemotherapy) do not seem to affect serum immunoglobulin levels. The observations implies that the extension and dissemination of tumor mass is the important factor for the change in serum immunoglobulin level in squamous cell carcinoma of the oral cavity.
Glucocorticoid‐induced exacerbation of metastatic human melanoma
Authors: Chaudhuri Prabir K. , Das Gupta Tapas K. , Beattie Craig W. , Walker Michael J. 
Published: February 2007

AbstractThe present study reports the effect of a potent glucocorticoid, dexamethasone, and the antiestrogen tamoxifen on the progression of metastatic melanoma in an adult male.
The chromosomal effects of the oral contraceptive
Authors: Bishun Nutan P. 
Published: February 2007

AbstractA general review of reports on the chromosomal effects of oral contraceptive has been undertaken, and it is quite apparent that there is a scarcity of literature on these very important investigations. Also, those that have been undertaken, cannot be properly assessed on account of, one supposes, subjects' background and lack of numbers, differences in techniques and, above all, the small number of metaphases analyzed.Apart from the report by Mills and colleagues [16], none of the reports mentioned exogenous agents to which the subjects might have been exposed, especially in cases where there has been an increased frequency of chromosomal aberrations. All these considerations must be taken into account for, as yet, the reports are too conflicting to ‚indict’︁ the oral contraceptive as having chromosome‐breaking properties.
Hodgkin's disease in Greece: A retrospective clinicopathologic study of 78 cases
Authors: Floros Demosthenes , Papakyriazis Nicolas , Boutis Lazaros , Symeonidis Alexandros 
Published: February 2007

AbstractThe Rye histologic classification of Hodgkin's disease has been applied retrospectively to a series of 78 previously untreated cases of Hodgkin's disease. The patients have been followed for periods varying from 1 to 12 years. Mixed cellularity was the most common histologic type. Nodular sclerosis had an intermediate frequency, and lymphocytic predominance and lymphocytic depletion showed the lowest incidence. The sex incidence showed a male predominance in all histologic types except the nodular sclerosis, where prevalence of females was noted. The study confirms the better prognosis of the lymphocytic predominance and nodular sclerosis in comparison with the poor prognosis of the mixed cellularity and the very poor prognosis of the lymphocytic depletion. Nodular sclerosis presented with higher incidence in the mediastinum; it occurred mainly in young females and it exhibited a relatively good prognosis, findings which support the accepted view that nodular sclerosis comprises a distinct clinical and biological type of the disease. A marked difference in the survival rates in Stages I and II as compared to those of Stages III and IV was found.
Desquamation of malignant cells in carcinoma of the uterine cervix: Its role in prognosis
Authors: Gupta Saroj , Gupta Y. N. , Rani Abha , Sanyal B. , Khanna S. 
Published: February 2007

AbstractPercentage of malignant cell exfoliation in relation to that of benign epithelial cells was studied in pretreatment vaginal smears of 251 patients of squamous cell carcinoma of the cervix. The rate of exfoliation did not increase with increasing clinical severity. Also, the various cell types of squamous cell carcinoma and clinical radiation response were independent of number of malignant cells shed in the vagina. However, the group of patients having a fewer number of malignant cells in their vaginal smears had a statistically significantly better five‐year survival.
The flexible implant in treatment of rectal carcinomas
Authors: Vider Manuel , Lim Nancy , Ditlow Richard , Au Francis , Gennaro Anthony R. 
Published: February 2007

AbstractA modified technique for removable afterloading Iridium‐192 implantation is described. Under local or general anesthesia, a series of flexible tygone tubes are introduced into all the tumor area in the rectum. This technique is especially suitable for palliation in high‐risk, elderly patients. No rectal tube is necessary in this technique.
A bottleneck of sputum cytology in mass survey for lung cancer: An approach to detect early stage lung cancer by sputum cytology
Authors: Hashimoto Takeshi , Sawamura Kenji , Furuse Kiyoyuki , Kawahara Masaaki , Kishida Toshiko , Teramoto Tomoaki , Kusunoki Yoko , Fukuoka Masahiro 
Published: February 2007

AbstractAiming at early detection of “hilar‐type” lung cancer by sputum examination, we examined the morphological characteristics of what we call “early cancer” cells which were observed in the sputum of 22 cases of hilar‐type early stage lung cancer. Two types of cells were found: “superficial‐type” cancer cells and “parabasal‐type” cancer cells. Cytological screening needs great care, because the cytoscreener is liable to mistake these cancer cells for normal‐ranged epithelial cells. It has become easier to detect early lung cancer by looking for not only superficial‐type cells but also parabasal‐type cells.
Localized magnetic‐loop induction hyperthermia of the rabbit brain
Authors: Silberman Allan W. , Morgan David F. , Storm F. Kristian , Rand Robert W. , Bubbers J. Eric , Brown W. Jann , Morton Donald L. 
Published: February 2007

AbstractThe Magnetrode magnetic‐loop applicator has been used for deep internal hyperthermia with minimal toxicity and without normal tissue injury. Until now, the effects of localized radiofrequency hyperthermia on the brain have not been adequately studied because of the potential hazards involved in trying to effect brain heating while preserving overlaying surface tissues. We found that normal rabbit brain could be heated to potentially tumoricidal temperatures (42–43°C) without apparent histopathologic or clinical damage to brain, skull, external eye, subcutaneous tissue, or skin.
Functioning paraganglioma in the organ of Zuckerkandl associated with esophagus carcinoma: A case report
Authors: Nishiyama Tatsuyoshi , Ono Minoru , Nohe Tomoyuki , Seo Yosuke , Hara Yasuhiro , Abe Muneaki , Hayashi Itsuro 
Published: February 2007

AbstractA case of extrameduflary pheochromocytoma in the organ of Zuckerkandl is reported. Moderately differentiated squamous cell carcinoma of the esophagus was found concomitantly. Despite the significant elevation of catecholamine levels in the plasma and urine, the value of vanillylmandelic acid was only slightly elevated.
Parotid gland metastatic carcinoma of breast origin
Authors: Wiesel Jochanan M. , Weshler Zeev , Sherman Yoav , Gay Isaac 
Published: February 2007

AbstractThree patients who presented with a clinically solitary intraparotid metastasis from breast carcinoma are reported. The entity of metastatic disease in the parotid gland is reviewed. The importance of histologic distinction between primary and metastatic neoplasms of the parotid and the treatment approach are stressed.
On the treatment and prognosis of malignant ascites: Is the survival time determined when the abdominal paracentesis is needed?
Authors: Appelqvist Pertti , Silvo Jouni , Salmela Liisa , Kostiainen Seppo 
Published: February 2007

AbstractWe review a series of 100 consecutive cases of malignancy treated for as cites with abdominal paracentesis. The results of treatment for ascites with intracavitary Thiotepa are reported for 23 patients. The temporary partial response rate was 8/23 (35%) patients. There were symptoms of intestinal obstruction in five patients (22%) treated with Thiotepa, and one of these patients died of intestinal obstruction. In 60% of autopsied patients there were abundant intestinal adhesions in the peritoneal cavity after Thiotepa. We concluded that Thiotepa is contraindicated for instillation into the peritoneal cavity. The median survival time for patients with carcinoma of the mammary gland was 47 days, carcinoma of the ovary 121 days, and carcinoma of the large intestine 54 days after the first abdominal paracentesis. We found that patients without clinical liver metastasis at the time of first abdominal paracentesis had almost three times longer median survival time than that of patients with metastatic liver. In four cases the immediate cause of death was a complication of an abdominal paracentesis.
The limitations of preoperative grading of rectal carcinoma
Authors: Chapuis P. H. , Newland R. C. , Dent O. F. , Jaworski R. , Watson D. , Pheils M. T. 
Published: February 2007

AbstractIn 103 patients who had a preoperative biopsy before resection of a single carcinoma of the rectum, the grading of the biopsy by one pathologist was compared to the definitive grade. Only 62% of the biopsies were correctly assessed, and the tendency was to underestimate the grade with few tumors being described correctly as high grade. This suggests that the grading of biopsy fragments has definite limitations and is of limited value when selecting patients for conservative treatment of rectal carcinoma.
Emergency pericardiotomy as primary diagnostic and therapeutic procedure in malignant pericardial tamponade: Report of three cases and review of the literature
Authors: Appelqvist P. , Maamies T. , Grohn P. 
Published: February 2007

AbstractThree cases are presented in which pericardial tamponade was the first indication of malignant disorder. The diagnosis and therapy of malignant cardiac tamponade was revealed by emergency pericardiotomy. In all cases the tumor was an adenomatous carcinoma and the site of primary tumor was unknown until death. The median survival time after onset of symptoms was 4 months. The primary site was the lungs in two and remained unknown autopsy in one case.
Preliminary trial of combination therapy with adriamycin and radiation in sarcomas and other malignant tumors
Authors: Sordillo Peter P. , Magill Gordon B. , Schauer Peter K. , Vikram Bhadrasain , Kim Jae H. , Hilaris Basil S. 
Published: February 2007

AbstractBased on reports of synergism between adriamycin and radiation therapy in experimental systems, a trial was initiated testing this combination in 53 adult patients with various advanced malignancies, especially sarcomas. Since studies have suggested a selective sensitization of hypoxic cells when this drug is given prior to radiation, an injection of low‐dose adriamycin was given 90 min before radiation. This treatment was repeated every 7 days. The combination was most effective in the 30 patients with soft‐tissue sarcomas, with 62% of these patients having partial or complete responses. Responses were less good in patients with gastric adenocarcinoma or with other tumors. The toxicity of the combined treatment was moderate. Further trials of this combination are warranted.
A model of experimental isolation perfusion using cis‐platinum
Authors: Wile A. G. , Guilmette E. , Friedberg H. , Mason G. R. 
Published: February 2007

AbstractAn animal model has been devised to investigate effects of hyperthermia and chemotherapeutic agents on normal and neoplastic tissue. This model uses the rabbit as the experimental animal and will permit the passage of the transplantable VX‐2 carcinoma. The technique described parallels clinical isolation‐perfusion and utilizes cis‐platinum as the chemotherapeutic agent. This model has proven to be reliable and consistent in achieving tissue temperature at therapeutic ranges and has documented the safety of using cis‐platinum in this mode of therapy.
Chondroma of the larynx
Authors: Schittek Anton , James Arthur G. 
Published: February 2007

AbstractChondroma of the larynx is rare, but should be suspected in elderly patients with persistent voice changes or recurrent colds when carcinoma has been disproved. We report a patient with chondroma of the larynx. The diagnosis was established following complications associated with anesthesia for an unrelated ailment.
The Management of breast carcinoma in pregnancy and lactation
Authors: Hornstein E. , Skornick Y. , Rozin R. 
Published: February 2007

AbstractUntil recent years, the prognosis for breast cancer in pregnancy and lactation was regarded as grave. The current new data suggest that pregnant women with early breast carcinoma may be treated in the same way as nonpregnant women without affecting pregnancy. However, women with breast cancer in their first trimester of pregnancy and in whom axillary lymph nodes are involved, should receive chemotherapy and have their pregnancy terminated. Toward the end of pregnancy, adjuvant therapy, when needed, can be delayed until after delivery. In patients with advanced disease pregnancy should be terminated and subsequent treatment initiated. During lactation, diagnosis of breast carcinoma requires suppression of lactation by means other than estrogens. The carcinoma will be treated by standard methods. After radical mastectomy for breast cancer, subsequent pregnancies are allowed but should be delayed until the period of greatest risk has passed.
Influences of operative stress on cell‐mediated immunity and on tumor metastasis and their prevention by nonspecific immunotherapy: Experimental studies in rats
Authors: Tanemura Hiromi , Sakata Kazuki , Kunieda Tokuro , Saji Shigetoyo , Yamamoto Satoru , Takekoshi Tomoharu 
Published: February 2007

AbstractInfluences of operative stress on nonspecific cell‐mediated immunity and on liability to tumor metastasis and preventive effects thereon of a non‐specific immunopotentiator OK‐432 were examined. Syngeneic female SD rats were inoculated SC with 200 mg of a transplantable mammary carcinoma MRMT‐1 at the dorsal flank. After 2 weeks the tumor was surgically excised simply or combined with 30‐min laparotomy. It was revealed by follow‐up examination that the laparotomy stress significantly increased incidence of postoperative lung metastasis. It was found that PHA‐induced blastogenesis of peripheral lymphocytes was markedly reduced in the early period following laparotomy. Preoperative or postoperative (especially the former) administration of OK‐432 was effective for preventing both the postlaparotomy facilitation of lung metastasis and the postlaparotomy reduction in PHA lymphoblastogenesis.
The effect of total body microwave hyperthermia and hepatic artery ligation on liver tumors—an experimental study in rats
Authors: Carlsson Goran , Hafström Larsolof , Hugander Anders , Jönsson Per‐Ebbe , Bolmsjö Magnus , Persson Bertil 
Published: February 2007

AbstractThe effect of general microwave hyperthermia and hepatic artery ligation (HAL) was tested on Wistar rats with a transplanted N‐methyl‐N‐nitroso‐guanidine‐induced adenocarcinoma in the liver. Total body hyperthermia (41.5°C for 1 hour, three times during 24 hours) was given on the same day as HAL, and 1, 2, and 3 days after. HAL induced a slower tumor growth than untreated controls. No additive effect was registered when total body microwave hyperthermia was added to HAL. When hyperthermia was added 2 days after HAL, there was a transient decrease in tumor volume as in the HAL series. Total body microwave hyperthermia added 3 days after HAL induced a faster tumor growth than after HAL alone. When hyperthermia was added the same day and 1 day after HAL, there was a 50% mortality.
Giant condyloma acuminatum (Buschke‐Lowenstein tumor) involving a pilonidal sinus: A case report and review of the literature
Authors: Norris C. S. 
Published: February 2007

AbstractGiant condyloma acuminatum or Buschke‐Lowenstein tumor has been reported to involve many areas about the perineum. The majority of previous documentations have implicated the coronal sulcus, prepuce, and fossa navicularis of the penis as the most likely foci to support growth. Authors have contributed multiple cases of perianal and rectal involvement as well as rare reports of inguinal, bladder, and endocervix‐low uterine segment tumors.A case of giant condyloma acuminatum involving a chronic pilonidal sinus overlying the sacrum is described. Wide surgical extirpation was found to be a curative means of management.