bluuebunny/crossref_metadata_2025_split huggingface dataset:
Identificación y caracterización de herramientas para evaluar la alergia a las penicilinas: Revisión estructurada
Authors: Osorio-Tapiero Liliana Marcela , Amariles Pedro , Holguín Hector , Salazar-Ospina Andrea , Ortiz Rendón Milena 
Published: March 2024

Introducción: Las reacciones alérgicas son uno de los problemas de seguridad más graves asociadas al uso de medicamentos, siendo la alergia a los antibióticos betalactámicos la más prevalente. Las pruebas de alergia a las penicilinas pueden ayudar a identificar pacientes hospitalizados y ambulatorios que podrían tolerar y usar de manera segura este grupo de antibióticos y evitar rótulos que limiten el uso de antibióticos betalactámicos por tiempo indefinido.
Objetivo: Identificar las herramientas disponibles en la literatura para valorar el antecedente de alergia a las penicilinas y proponer una herramienta que consolide la información extraída.
Metodología: Revisión estructurada en PubMed/MEDLINE entre 1 junio 2015 hasta 30 noviembre 2022, utilizando los términos MeSH: (((“skin tests”[MeSH Terms]) OR (“skin irritancy tests”[MeSH Terms])) AND (“penicillins”[All Fields])) AND (“drug hypersensitivity”[MeSH Terms]). Publicaciones en inglés y español con acceso a texto completo y estudios realizados en humanos, sobre herramientas disponibles para evaluar la alergia a penicilinas fueron incluidos.
Resultados: Se identificaron 201 artículos, de los cuales se incluyeron 108. Dentro de las herramientas para evaluar la alergia a las penicilinas se identificaron: a) pruebas in vivo: pruebas cutáneas, pruebas de provocación oral, pruebas del parche; y b) pruebas in vitro: pruebas de IgE específica, determinación de triptasa, histamina. De los 1181 pacientes reportados con alergia a las penicilinas, sólo el 2 % de ellos se confirmó la presencia de alergia.
Conclusión: Las pruebas cutáneas y de provocación oral sumado a algunas combinaciones in vivo/in vitro, fueron las herramientas más utilizadas para evaluar la alergia a las penicilinas.
Climate Change and Community Resilience: Insights from South Asia
Authors: Shrestha Kiran 
Published: March 2024

This book presents case studies, stories and examples of climate change adaptation initiatives from seven South Asian countries—Bangladesh, Bhutan, India, Maldives, Nepal, Pakistan, and Sri Lanka—highlighting traditional and indigenous knowledge with community engagement. The book has 27 studies (chapters) organized under six themes (Parts): concepts and models; traditional knowledge and sustainable agriculture; technology adoption; disaster risk reduction; urban sustainability; and alternative livelihoods.
Impact of Shoes Brand Preference on Customer Satisfaction
Authors: Goet Joginder , Kharel Kiran 
Published: March 2024

In a competitive business environment, concerns like customer satisfaction and brand preferences are becoming very important to corporate operations. The core objective of this research was to look at the influence of factors of brand preference on Customer Satisfaction with shoes. Primary data were employed in the research. Correlation and regression were utilized to calculate, analyze, and interpret the data for the descriptive and causal-comparative research design. The entire population is used in the study as shoe users. The population was represented by a sample of 390 respondents. A convenience sampling method was used to determine the sample size. According to the findings, brand preference factors such as Product Quality (PQ), Design (DG), Store Environment (SE), Service Quality (SQ), Promotion (PR), and Brand Image (BI) have a considerable impact on Customer Satisfaction in the Kathmandu Valley. But one factor, Brand Name (BN) has no considerable impact on Customer Satisfaction. The outcomes of this study show the significant link between factors of brand preference and Customer Satisfaction in the Kathmandu Valley. The Pearson coefficient between Brand Name (BN), Product Quality (PQ), Design (DG), Store Environment (SE), Service Quality (SQ), Promotion (PR), and Brand Image (BI) has been determined to be positive by correlation analysis.Because the value of significance was less than 0.05, all alternative hypotheses were accepted. As a result, we may deduce that the interactions positively impact Customer Satisfaction. Brand preference factors except for Brand Name (BN) have a significant influence on Customer Satisfaction.
IMPACT OF STAPHYLOCOCCUS SPP. ON OCCURRENCE OF INFECTIOUS INFLAMMATORY PROCESSES IN SURGICAL PATIENTS: A BACTERIOLOGICAL STUDY
Authors: Fedorchenko V. I. , Loban G. A. , Hancho O. V. , Chapala A. M. , Syvovol V. M. 
Published: March 2024

Introduction. Staphylococci are well-known pathogens associated with purulent-inflammatory processes at various body sites. However, the specific contributions of different microorganisms within microbial communities remain poorly understood. Notably, these diverse microbes can exhibit distinct antibiotic susceptibility profiles due to their varying taxonomic classifications.
The purpose of this study is to analyze the results of bacteriological examination of pathological material taken from patients in surgical department and to assess the contribution of S. aureus and coagulase-negative staphylococci in the form of mono- and mixed infection in the cases of infectious pathology.
Results and discussion. 123 samples were obtained from patients in the surgical department; cultures of Staphylococcus bacteria were isolated in 37 cases, which accounted for 30.1% of all studies. Staphylococcus aureus was identified in 18 cultures (14.6%), with 11 isolates (8.9%) found as single infections (monoculture) and 7 isolates (5.7%) identified within mixed microbial communities. Additionally, 19 isolates (15.4%) were identified as coagulase-negative staphylococci. These microbial communities comprised 2 to 4 different types of microorganisms.
Conclusion. Staphylococcus spp. were isolated from 30.1% of patients in the surgical department. Among these isolates, Staphylococcus aureus was present in 38.9% of mixed microbial cultures, while coagulase-negative staphylococci were found in 33.3% of Staphylococcus isolations. Notably, S. aureus and coagulase-negative staphylococci were never co-isolated within the same mixed culture.
ENHANCING QUALITY OF MEDICAL EDUCATION THROUGH INNOVATIVE TECHNOLOGIES
Authors: Іліка В.В. , Harvasiuk O.V. , Dogolych O.I. , Kulachek V.T. , Andrushchak M.O. 
Published: March 2024

Objectives. The advancement of education is propelled by the integration of new ideas, tools, pedagogical methods, and management technologies, contibuting to a transformation of the education system. This scientific paper aims to explore the significance of innovations and their pivotal role in enhancing the quality of education, particularly through the implementation of innovative approaches in delivering the course "Pathomorphology" for future medical professionals.
Results. The study findings unequivocally demonstrate that adopting an innovative approach in teaching "Pathomorphology" significantly contributes to the development of students' professional knowledge and fosters the cultivation of critical thinking and analytical skills. Leveraging advanced methodologies such as integrated learning and group learning technologies creates a dynamic learning environment wherein students collaborate, exchange ideas, and collectively address practical challenges.
An important component is the utilization of the MOODLE system and online platforms like Google Meet, enabling students to access knowledge electronically while actively engaging with lecturers in a virtual setting. This facilitates communication between students and educators, fostering discussions, nurturing creative thinking, and tackling educational tasks collaboratively.
Conclusion. Integrating innovative approaches in education enhances the quality of student learning, encouraging theri active research, fostering independent learning skills, and cultivating self-reliant individuals capable of continuous self-improvement. The consistent implementation of innovations not only enhances students' professional competence but also imposes high standards on educators, motivating them to pursue continuous professional development and strive for excellence. These factors render the teaching-learning process not only engaging but also exceptionally effective.
САКСОФОН У МУЗИЧНІЙ КУЛЬТУРІ КИТАЮ
Authors: Haoyuan Wang 
Published: March 2024

Мета роботи. У статті досліджуються історія та специфіка розвитку мистецтва гри на саксофоні в Китаї. Методологія дослідження представляє застосування естетико-культурологічного, історичного, компаративного та музикознавчого методів, а також виконавського підходу. У комплексі вони утворюють єдину методологічну базу. Наукова новизна роботи визначається виявленням основних рис саксофонного мистецтва в сучасній китайській професійній музичній творчості. Висновки. Історичне становлення китайської саксофонної школи відбувалося, з одного боку, завдяки об'єктивним органологічно-звуковим та технічним можливостям інструменту; з іншого – через ентузіазм китайських музикантів (професіоналів у сфері інших видів духового інструменталізму чи захоплених початківців); з третього – внаслідок щільного контакту з професіоналами-іноземцями, передусім, представниками американської та французької саксофонних шкіл. У цілому можна констатувати, що інструментально-технічні, звукові та ідейні засади даних провідних світових шкіл гри на саксофоні були досить повноцінно освоєні китайськими музикантами, що сприяло висуненню на світові концертні майданчики китайських саксофоністів. Їх виконавська, педагогічна та, певним чином, наукова діяльність стали талантовитою безпосередньою адаптацією мисленнєво-артистичних та інструментально-технологічних устремлінь своїх учителів до умів китайської музичної культури. Характерні для саксофону процеси триваючої модифікації інструменту через тенденції до оновлення виконавсько-виразових можливостей інструменту та виконавської техніки за рахунок впровадження нових прийомів гри та особливих ігрових ефектів (що яскраво простежується в музичному дискурсі від другої половини ХХ століття) безпосередньо пов'язані із пошуками композиторів у сфері нових, багато в чому незвичайних темброво-звукових можливостей музичної тканини, які найбільш якісно втілилися у сольних та камерно-інструментальних творах для саксофону. Для китайської композиторської поетики, з її посиленням ролі національного початку, саксофонний репертуар набуває своїх властивостей. Путь становлення репертуару, як і у випадку з творами для інших академічних музичних інструментів, відбувався у напрямку від обробки національних мелодій до оригінальних творів високого художнього змісту.
Factors Affecting The Incidence of Anemia in Pregnancy During The COVID-19 Pandemic
Authors: Gunawan Lucia Sincu , Rahmawati Juvita Tri , Puspita Rumeyda Chitra 
Published: March 2024

Anemia during pregnancy carries the risk of premature birth, low birth weight, and fetus malformations and can impose additional costs on society and families. The prevalence of anemia would be the best indicator to monitor pregnant women’s health and prevent pregnancy complications. The COVID-19 pandemic has impacted pregnant women. The prevalence of anemia in pregnancy increased from 38.33% in 2019 to 49.21% in 2020. In the COVID-19 pandemic situation with social activity restrictions, decreasing family income, and limited access to health services, suffering from COVID-19 are risk factors for increasing the incidence of anemia in pregnancy. This study aimed to determine factors affecting the incidence of anemia in pregnancy during the COVID-19 pandemic in Karangrejo District, Magetan Regency. This study was an observational analytic study with a cross-sectional study design. The sample was selected by purposive sampling with a sample size of 52 study subjects. Data were analyzed using logistic regression analysis with SPSS. Factors that increased the incidence of anemia in pregnancy during the COVID-19 pandemic were pregnancy interval (OR=17.67; CI 95%= 1.01 to 116.00; p=0.049), gestational age (OR=11.39; CI 95% 1.12-116.00; p= 0,040), animal protein intake (OR= 0.25; CI 95% 0.03 – 2.38; p= 0,044), iron supplementation (OR= 108.47; CI 95% 2.36 – 4978.68; p= 0,016), consumption of tea (OR=36,89; CI95% 1.57 to 868.41; p=0.025). Mothers’ education, family income, parity, frequency of ANC visits, and COVID-19 morbidity do not significantly affect the incidence of anemia in pregnancy. There were effects of pregnancy interval, gestational age, animal protein intake, iron supplementation, and consumption of tea on the incidence of anemia in pregnancy during the COVID-19 in Karangrejo District, Magetan Regency. Keywords: anemia;pregnancy;COVID-19
Hubungan antara Gula Darah Sewaktu dan Faal Paru pada Pasien Diabetes Melitus di Puskesmas Jumpandang Baru Makassar
Authors: Shavira MD  , Dwi Anggita  , Khalid Nur Fadhillah , Wiriansya Edward Pandu , Yani Sodiqah  , Hasan  , Happy Laurentz  
Published: March 2024

Latar belakang: Hiperglikemi kronik dapat menimbulkan hambatan proses pertukaran O2 dan CO2 di paru akibat adanya penumpukan protein berupa kolagen di pembuluh darah. Sehingga kecepatan difusi alveoli pada paru pasien diabetes akan berkurang. Tujuan: Penelitian ini bertujuan mengetahui hubungan antara gula darah sewaktu dan faal paru pada pasien DM di Puskesmas Jumpandang Baru Makassar April-Mei 2019. Metode: Penelitian ini menggunakan desain analitik korelatif kategori, dengan pendekatan cross sectional. Sampel dalam penelitian ini adalah pasien diabetes melitus sebanyak 32 orang yang memenuhi kriteria inklusi dan eksklusi. Teknik sampling yang digunakan adalah accidental sampling. Alat ukur yang digunakan adalah alat ukur berat badan, alat ukur tinggi badan, alat ukur gula darah Autocheck dan spirometer BTL 08 MT Plus. Hasil : Dari 32 subjek penelitian didapatkan sampel kadar gula darah sewaktu tinggi dengan derajat derajat restrictive severe sebesar 80% (8 dari 10 responden), dan derajat restrictive moderate sebesar 20% (2 dari 10 responden) sedangkan pasien diabetes melitus yang kadar gula darah sewaktunya rendah dengan derajat restrictive severe sebesar 32% (7 dari 22 responden), derajat restrictive moderate 36% (8 dari 22 responden), derajat restrictive mild sebesar 5% ( 1 dari 22 responden), serta dalam keadaan faal paru normal sebesar 27% ( 6 dari 22 responden). Kesimpulan: Berdasarkan hasil uji Chi-Square menunjukkan tidak ada hubungan yang signifikan antara kadar gula darah sewaktu dengan kapasitas vital paru pada pasien diabetes mellitus (nilai p=0.067).
Pengaruh Terapi Bekam Terhadap Kadar Kolesterol Total Pada Pasien Hiperkolesterolemia di Klinik Hamdalah Makassar
Authors: Uda'a Rizka , Dahliah  , Edward Pandu Wiriansya  , Rahmawati  , Rezky Putri Indarwati  
Published: March 2024

Hiperkolesterolemia merupakan suatu kondisi yang dapat meningkatkan terjadinya risiko penyakit jantung koroner, stroke, tekanan darah tinggi, kegemukan dan masalah kesehatan lainnya. Mahalnya obat dan tingginya efek samping pengobatan farmakologis sehingga membutuhkan pengobatan alternatif penurunan kadar kolesterol total secara non farmakologis yaitu terapi bekam yang dianjurkan oleh Nabi Muhammad Shallallahu ‘alaihi wassalam serta seiring berjalannya waktu terapi bekam telah dimodernkan dan mengikuti kaidah ilmiah.Tujuan pada peneltian ini untuk mengetahui pengaruh terapi bekam terhadap penurunan kadar kolesterol total pada pasien hiperkolesterolemia di klinik hamdalah bekam dan ruqyah syar’iyyah kota makassar tahun 2023. Penelitian ini menggunakan pendekatan kuantitatif metode eksperimen dengan teknik total sampling berdasarkan data pasien bekam riwayat hiperkolesterolemia bulan desember 2022 dengan jumlah sampel sebanyak 36 pasien. Berdasarkan Hasil penelitian didapatkan perubahan kadar kolesterol Sebanyak 30 responden (83,3%) mengalami penurunan kadar kolesterol total setelah mengikuti terapi bekam, sedangkan 6 responden (16,7%) mengalami peningkatan kadar kolesterol total. Adanya pengaruh penurunan kadar kolesterol total yang signifikan pada pasien hiperkolesterolemia di klinik hamdalah bekam dan ruqyah syar’iyyah makassar tahun 2023.
Editorial
Authors: Cadernos do Tempo Presente Editores 
Published: March 2024

A Cadernos do Tempo Presente chega sua segunda edição do ano de 2023. Nela, contamos com artigos e resenhas que nos apresentam pesquisas na área de História do Tempo Presente. Esta edição também marca a mudança da identidade visual da revista com a adoção de uma novo logo e de um novo modelo de diagramação.
No primeiro artigo, por meio de um estudo baseado na análise de documentos e da literatura produzida por organizações governamentais ou não, bem como por entrevistas com especialista sobre o tema, Karl Schurster e Luzilete Falavinha Ramos nos apresentam reflexões sobre a história do ensino do holocausto transcorrendo por suas origens, temas e métodos. A seguir, Dilton Candido Santos Maynard e Diego Leonardo Santana Silva nos mostram como a Guerra Fria foi representada no universo de Batman com um estudo sobre o clássico quadrinho O Cavaleiro das Trevas, de Frank Miller.
No terceiro artigo da edição, Luís Fellipe F. Afonso expõe um estudo sobre o rock e a censura na década de 1980. O texto demonstra como o regime utilizada a censura para cercear pensamentos críticos, sendo o BRock um dos gêneros musicais mais censurados da época visando reprimir os artistas em prol de ideias favoráveis à ditadura. A seguir Felipe Cazetta traz uma análise da atuação de Jacques Ploncard D’Assac, um mediador entre os salazaristas e os estrangeiros, entre eles os franquistas, durante o regime de Salazar em Portugal no período após a Segunda Guerra Mundial.
Já Lucas Alves da Silva traz um estudo sobre a preocupação dos militares brasileiros durante a abertura política e os receios por parte de atores do regime com uma eventual punição por crimes cometidos contra os Direitos Humanos. Silva reflete sobre o posicionamento dos militares e políticos em relação ao tema por meio da análise de publicações nos jornais Diário do Paraná e Correio de Notícias. E, em no último artigo, temos Júlia Amaral Amato Moreira trabalhando com memórias de filhos de sobreviventes do Holocausto em relatos orais, entendidos sob a ótica da Pós-memória extraídos de filhos de sobreviventes do Holocausto em Belo Horizonte.
Por fim, completamos nossa edição com a resenha do livro Governança e Sustentabilidade de Renato Cader e Teresa Villac escrita por Maralysa Correia de Souza Cavalcanti.
Agradecemos aos nossos parceiros, leitores e colaboradores e desejamos uma ótima leitura.

Atenciosamente,
Os editores.
FAKTOR-FAKTOR YANG BERHUBUNGAN DENGAN MUTU PELAYANAN RUMAH SAKIT TERHADAP KEPUASAN PASIEN DI RUANG RAWAT INAP RSKD IBU DAN ANAK PERTIWI MAKASSAR
Authors: Liliskarlina Liliskarlina , Faisal Faisal , AR. Andi Kayani 
Published: March 2024

Mutu pelayanan rumah sakit menjadi salah satu faktor penting untuk menciptakan kepuasan pasien. Pelayanan yang berkualitas dalam konteks pelayanan di rumah sakit adalah memberikan pelayanan kepada pasien dan keluarganya sesuai dengan standar kualitas.Penelitian ini bertujuan untuk mengetahui hubungan mutu pelayanan rumah sakit berdasarkan faktor dimensi kompetensi teknis, akses terhadap pelayanan, kenyamanan, hubungan antar manusia, dan ketepatan waktu terhadap kepuasan pasien di ruang rawat inap RSKD Ibu dan Anak Pertiwi Makassar. Jenis penelitian ini adalah penelitian kuantitatif dengan menggunakan desain cross sectional study. Pengambilan sampel menggunakan accidental sampling, diperoleh sampel sebanyak 175 responden. Analisis data menggunakan uji chi-square dengan α= 0,05.Berdasarkan hasil penelitian menunjukkan bahwa ada hubungan antara dimensi kompetensi teknis (p= 0,001), akses terhadap pelayanan (p= 0,001), hubungan antar manusia (p= 0,003), dan ketepatan waktu (p= 0,036) terhadap kepuasan pasien di ruang rawat inap Rumah Sakit Khusus Daerah Ibu dan Anak Pertiwi Makassar, dan tidak ada hubungan antara dimensi kenyamanan (p= 0,185) terhadap kepuasan pasien di ruang rawat inap Rumah Sakit Khusus Daerah Ibu dan anak Pertiwi Makassar.Disarankan kepada Rumah Sakit Khusus Daerah Ibu dan Anak Pertiwi Makassar memperhatikan pengunjung yang membawa anak usia dibawah 12 tahun sehingga tidak mengganggu kenyamanan pasien maupun pengunjung lain.
Clinical distribution of carbapenem genotypes and resistance to ceftazidime-avibactam in Enterobacteriaceae bacteria
Authors: Zhu Xueyun , Guo Caixia , Xu Shengxi , Lv Fei , Guo Zhusheng , Lin Sisi , Yang CongZhu , Deng Zhuliang , Chen Shaofeng , Huang Ya , Zhao Zuguo , Li Lu 
Published: March 2024

IntroductionBacterial resistance is a major threat to public health worldwide. To gain an understanding of the clinical infection distribution, drug resistance information, and genotype of CRE in Dongguan, China, as well as the resistance of relevant genotypes to CAZ-AVI, this research aims to improve drug resistance monitoring information in Dongguan and provide a reliable basis for the clinical control and treatment of CRE infection.MethodsVITEK-2 Compact automatic analyzer was utilized to identify 516 strains of CRE collected from January 2017 to June 2023. To determine drug sensitivity, the K-B method, E-test, and MIC methods were used. From June 2022 to June 2023, 80 CRE strains were selected, and GeneXpert Carba-R was used to detect and identify the genotype of the carbapenemase present in the collected CRE strains. An in-depth analysis was conducted on the CAZ-AVI in vitro drug sensitivity activity of various genotypes of CRE, and the results were statistically evaluated using SPSS 23.0 and WHONET 5.6 software.ResultsThis study identified 516 CRE strains, with the majority (70.16%) being K.pneumoniae, followed by E.coli (18.99%). Respiratory specimens had highest detection rate with 53.77% identified, whereas urine specimens had the second highest detection rate with 17.99%. From June 2022 to June 2023, 95% of the strains tested using the CRE GeneXpert Carba-R assay possessed carbapenemase genes, of which 32.5% were blaNDM strains and 61.25% blaKPC strains. The results showed that CRE strains containing blaKPC had a significantly higher rate of resistance to amikacin, cefepime, and aztreonam than those harboring blaNDM.ConclusionsThe CRE strains isolated from Dongguan region demonstrated a high resistance rate to various antibiotics used in clinical practice but a low resistance rate to tigecycline. These strains produce Class A serine carbapenemases and Class B metals β-lactamases, with the majority of them carrying blaNDM and blaKPC. Notably, CRE strains with blaKPC and blaNDM had significantly lower resistance rates to tigecycline. CAZ-AVI showed a good sensitivity rate with no resistance to CRE strains carrying blaKPC. Therefore, CAZ-AVI and tigecycline should be used as a guide for rational use of antibiotics in clinical practice to effectively treat CRE.