bluuebunny/crossref_metadata_2025_split huggingface dataset:
Different expression of caspase‐3 in rat hippocampal subregions during postnatal development
Authors: Liu Jin Ping , Chang Li Rong , Gao Xiu Lai , Wu Yan 
Published: May 2008

AbstractRecent studies indicate that caspase‐3 has distinct characteristics in postmitotic and neuronal progenitor apoptosis. Pyramidal neurons in CA1 and CA3 of the hippocampus become postmitotic during early postnatal development, whereas granule cells in the dentate gyrus (DG) undergo self‐renewal throughout life. The distribution of caspase‐3 in the hippocampal subfields during postnatal development is largely unknown. We used immunofluorescent staining for two isoforms of caspase‐3 (an active 17 kDa isoform and an inactive 35 kDa precursor) and the Hoechst 33342 staining for nuclear chromatin to assess caspase‐3 expression in the CA1, CA3, and DG of rat hippocampus during postnatal development. The expression of active caspase‐3 reached a peak at P7 in CA1, at P2 in CA3, and then decreased with age. Whereas in DG, active caspase‐3 expression increased slightly after P7, and remained at high levels for the rest of the investigated period. Procaspase‐3 immunoreactivity was strong at P2 and decreased gradually to a basal plateau by P21 in the three regions examined. In addition, the number of apoptotic cells in the three regions all reached maximum levels at P7, and then decreased with age. These data indicate that there were specific spatio‐temporal patterns of expression of active and precursor caspase‐3 in the postnatally developing rat hippocampal subregions, and that the activation of caspase‐3 in neuronal progenitor cells of DG and that in the postmitotic neurons of CA1 and CA3 may have distinct roles and mechanisms during postnatal development. Microsc. Res. Tech., 2008. © 2008 Wiley‐Liss, Inc.
Function‐preserving parotid surgery for benign tumors involving the deep parotid lobe
Authors: Roh Jong‐Lyel , Park Chan Il 
Published: May 2008

AbstractBackgroundParotid deep lobe tumors have usually been removed by total parotidectomy, which has functional and aesthetic side effects. Limited partial parotidectomy may result in fewer side effects.MethodsWe evaluated functional outcomes in 19 patients undergoing limited partial parotidectomy for benign tumors, 11 with deep lobe tumors and 8 with tumors involving both superficial and deep lobes, who underwent partial parotidectomy with preservation of normal glandular parenchyma and limited dissection of the facial nerve. Complications and salivary and cosmetic functions were evaluated at 6 and 12 months after surgery.ResultsMedian operation time was 1.5 hr. Five patients experienced temporary facial weakness, and 1 developed Frey's syndrome. All patients experienced full recovery of facial nerve function within 6 months. Mean stimulated parotid salivary flow on the operated side was 74% of the preoperative level. All patients had symmetrical facial contours without sunken defects. No patient had tumor recurrence after a median follow‐up of 40 months.ConclusionLimited resection of benign tumors involving the parotid deep lobe may result in improved functional outcomes, including preserved salivary flow and beneficial cosmetic aspects, without compromising local tumor control. J. Surg. Oncol. 2008;98:42–45. © 2008 Wiley‐Liss, Inc.
The functional −443T/C osteopontin promoter polymorphism influences osteopontin gene expression in melanoma cells via binding of c‐Myb transcription factor
Authors: Schultz Julia , Lorenz Peter , Ibrahim Saleh M. , Kundt Günther , Gross Gerd , Kunz Manfred 
Published: May 2008

AbstractIn the present report, the possible role of a recently described functional polymorphism of the osteopontin (OPN) promoter at position −443 (−443T/C) for OPN expression in melanoma cells was addressed. As shown by real‐time PCR analysis, melanoma metastases that were homozygous for the −443C allele expressed significantly higher levels of OPN mRNA compared with those that were either heterozygous (−443T/C) or homozygous for the −443T allele. In line with this, immunoblotting showed significantly enhanced baseline and bFGF‐induced OPN protein expression in melanoma cell lines which were homozygous for the −443C allele, compared with cell lines with other allelic variants. Similar results were obtained in in vitro luciferase assays. Chromatin immunoprecipitation (ChIP) demonstrated binding of c‐Myb to the −443 OPN promoter region, and binding could significantly be enhanced after bFGF stimulation. Moreover, as shown by electrophoretic mobility shift assays (EMSA), recombinant DNA‐binding domain of c‐Myb bound in a sequence‐specific manner to this region. Finally, the role of c‐Myb for OPN gene regulation via binding to the −443 promoter region could be further substantiated by ectopic overexpression of c‐Myb in melanoma cells, using different reporter gene constructs. Taken together, it is demonstrated that the −443 promoter region exerts influence on OPN gene expression in melanoma cells, and differential binding of c‐Myb transcription factor appears to play a major role in this process. These findings might be a feasible explanation for different OPN expression levels in metastatic tumors and may also have prognostic and therapeutic relevance. © 2008 Wiley‐Liss, Inc.
Identification of differentially expressed genes in the uterine endometrium on day 12 of the estrous cycle and pregnancy in pigs
Authors: Ka Hakhyun , Seo Heewon , Kim Mingoo , Choi Yohan , Lee Chang‐Kyu 
Published: May 2008

AbstractMaternal recognition of pregnancy in pigs occurs approximately on Day (D) 12 of pregnancy and is critical for embryo implantation. The presence of the conceptus in the uterine lumen during this period changes uterine endometrial function to prepare for attachment of the conceptus to the endometrial epithelial cells and maintain luteal function in the ovary. Although much is known about endometrial gene expression, the genes expressed in the uterine endometria and the cellular and molecular mechanisms of those gene products during the period of implantation and maternal recognition of pregnancy in pigs are still not completely defined. To better understand the interactions between the maternal uterus and conceptus during the implantation process, we searched genes differentially expressed in the endometria on D12 of pregnancy compared to those on D12 of the estrous cycle. A new reverse transcription‐polymerase chain reaction (RT‐PCR)‐based method that involves annealing control primers (ACPs) was employed. Using 120 ACPs, we sequenced 12 differentially expressed genes (DEGs) and identified those genes using the Basic Local Alignment Search Tool (BLAST). Northern blot hybridization analysis confirmed the differential expression of those DEGs in the uterine endometrium. In situ hybridization analysis determined the cell‐type specific expression of the DEGs in the uterine endometrium. Further analysis of the DEGs found in this study will provide insights into the cellular and molecular basis of maternal and fetal interactions during the period of maternal recognition of pregnancy in the pig. Mol. Reprod. Dev. 76: 75–84, 2009. © 2008 Wiley‐Liss, Inc.
Sojourn times in G/M/1 fork‐join networks
Authors: Ko Sung‐Seok , Serfozo Richard F. 
Published: May 2008

AbstractWe consider a processing network in which jobs arrive at a fork‐node according to a renewal process. Each job requires the completion of m tasks, which are instantaneously assigned by the fork‐node to m task‐processing nodes that operate like G/M/1 queueing stations. The job is completed when all of its m tasks are finished. The sojourn time (or response time) of a job in this G/M/1 fork‐join network is the total time it takes to complete the m tasks. Our main result is a closed‐form approximation of the sojourn‐time distribution of a job that arrives in equilibrium. This is obtained by the use of bounds, properties of D/M/1 and M/M/1 fork‐join networks, and exploratory simulations. Statistical tests show that our approximation distributions are good fits for the sojourn‐time distributions obtained from simulations. © 2008 Wiley Periodicals, Inc. Naval Research Logistics, 2008
A methyl‐deficient diet modifies histone methylation and alters Igf2 and H19 repression in the prostate
Authors: Dobosy Joseph R. , Fu Vivian X. , Desotelle Joshua A. , Srinivasan Rajini , Kenowski Michelle L. , Almassi Nima , Weindruch Richard , Svaren John , Jarrard David F. 
Published: May 2008

AbstractBackgroundFolate and methyl‐group deficiency has been linked to prostate cancer susceptibility, yet the mechanisms underlying these observations are incompletely understood. The region of the genome containing the imprinted genes insulin‐like growth factor 2 (Igf2) and H19, both of which display oncogenic functions, may be particularly sensitive to environmental influences.MethodsTo determine whether a methyl‐deficient diet impacts epigenetic controls at the Igf2–H19 locus, we placed C57BL/6 mice containing a polymorphism at the imprinted Igf2–H19 locus on a choline and methionine deficient (CMD) diet. We interrogated this locus for expression and epigenetic changes in prostate tissues.ResultsA significant increase in both Igf2 and H19 expression was found in CMD prostate tissues compared to controls. These expression changes were reversible with shorter exposure to the CMD diet. Chromatin immunoprecipitation (ChIP) revealed significant decreases in repressive histone modifications (dimethyl‐H3K9) within the H19 promoter, as well as Igf2 P2 and P3 promoters. DNA methylation within these promoters was not altered. No significant change in Igf2 or H19 imprinting was observed.ConclusionsThese findings highlight the plasticity of the epigenome in an epithelial organ vulnerable to neoplastic change. They further suggest that chromatin modifications are more susceptible to methyl‐deficient diets than DNA methylation at this locus. Prostate 68: 1187–1195, 2008. © 2008 Wiley‐Liss, Inc.
Effect of Mn2+ spin frustrations on spin dynamics of charge carriers in (BEDT‐TTF)2Mn[N(CN)2]3 crystals
Authors: Morgunov Roman , Kurganova Evgenia , Mushenok Fedor 
Published: May 2008

AbstractThe effect of spin frustrations of Mn2+ planar lattice on the spin relaxation rate in conductive BEDT‐TTF layers was observed. Layer‐to‐layer exchange availability was proved. Critical field of spin flop transition Hc = 32 kOe measured in our experiments makes it possible to estimate the interplanar exchange interaction as ∼10–3 K. Indirect interplanar exchange occurs through BEDT‐TTF layers due to spin polarization of conducting band electrons contributing to the exchange interaction. (© 2008 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
Spin‐wave spectra and magnetization of ferro–ferrimagnetic double layers
Authors: Jiang Wei , Wang Wei , Zhang Fan , Jiang Yuan , Guo An‐Bang 
Published: May 2008

AbstractThe spin‐wave spectra and magnetization of the ferro–ferrimagnetic double layers are studied by using a linear spin‐wave approximation and retarded Green's‐function method. We obtain the four branches of the spin‐wave spectra. Two energy gaps are found to exist in the energy band. The effects of the interlayer exchange coupling, the intralayer exchange coupling and the spin quantum numbers on the spin‐wave spectra and the energy gaps are discussed. The minimum (maximum) value point on the spin‐wave spectra and energy gaps correspond to a system that has a high symmetrical magnetic structure and the balance of quantum competitions among the exchange couplings and the spin quantum numbers of the system. There is a crossover between sublattice magnetizations in ferromagnetic layer that is affected by quantum fluctuations, thermal fluctuations and frustration of spins. (© 2008 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
Soft mode in PMN–PSN ceramics
Authors: Macutkevic J. , Grigalaitis R. , Adomavicius R. , Krotkus A. , Banys J. , Valusis G. , Bormanis K. , Sternberg A. 
Published: May 2008

AbstractVarious ordered and disordered (1–x)Pb(Mg1/3Nb2/3)O3 –x Pb(Sc1/2Nb1/2)O3 (PMN–PSN) ceramics were studied by THz transmission spectroscopy in the temperature range of 10–300 K. It is found that the dielectric relaxation dominates in the spectra in higher temperatures, T > 170 K. In contrast, below 150 K, the strength of relaxation becomes so weak that the phonon contribution can be separated. The phonon contributribution in the investigated frequency range (200 GHz–2 THz) is presumably caused by the E component of the Last mode. The component exhibits hardening on cooling in all investigated ceramics and its critical temperature in ferroelectric PMN–PSN ceramics (x = 1, 0.95) is lower than the critical temperature in PMN–PSN relaxors (x = 0.2). (© 2008 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
Reactions of Cationic Isocyanide Platinum(II) Complexes with Water (from Hexafluoroacetone‐hydrate): Carboxamido and Isocyanato Complexes
Authors: Fehlhammer Wolf Peter , Bartel Klaus , Metzner Robert , Beck Wolfgang 
Published: May 2008

AbstractThe isocyanide complexes $\rm[Pt(Cl)(C{\equiv}NR)(PPh_{3})_{2}]^{+}BF^{-}_{4}$ (R = CH2CO2Et, CH2Ph, C6H11, CH2SO2C6H4‐p‐Me) react with hexafluoroacetone‐sesquihydrate, (F3C)2CO·1,5 H2O, in the presence of triethylamine to give the carboxamido (carbamoyl) complexes [Pt(Cl){C(=O)NHR}(PPh3)2]. Under the same conditions the isocyanoamine complexes trans‐$\rm[Pt(Cl)(C{\equiv}N-NR_{2})(PPh_{3})_{2}]^{+}BF^{-}_{4}(R = Et, Pr^{i}, 2R = \overline {CH(Me)(CH_{2})_{3}C} H(Me))$ are transformed into the isocyanato complex trans‐[Pt(Cl)(NCO)(PPh3)2].
Chiral and Achiral Malate Frameworks with Different Dimensionalities
Authors: Ghosh Anupama , Rao C. N. R. 
Published: May 2008

AbstractA hybrid chain compound of the formula [Sr(L‐ C4H4O5)·3H2O]·H2O (1) and a hybrid double layered compound of the formula [Pb(L‐ C4H4O5)] (2) both with chiral structures, have been prepared strarting with L‐ malic acid, and characterized by X‐ray crystallography and other techniques. An achiral three‐dimensional hybrid compound of the composition [Pb(D,L‐ C4H4O5)·2H2O] (3) has been obtained starting with D, L‐ malic acid. A chiral coordination polymer of CuII with the formula [Cu3(L‐C4H3O5)2·4H2O]·2H2O (4) has also been characterized. The structures as well as the novel coordination modes exhibited by 1–4 are discussed.
Diradical Bis‐o‐iminosemiquinonato Zinc Complex: Spectroscopy, Magneto‐ and Electrochemistry
Authors: Poddel'sky A. I. , Smolyaninov I. V. , Skatova A. A. , Lukoyanov A. N. , Fukin G. K. , Berberova N. T. , Cherkasov V. K. , Abakumov G. A. 
Published: May 2008

AbstractBis‐o‐iminobenzosemiquinonato zinc and cadmium complexes M(ISQ‐Pri)2 (M = Zn, 1; M = Cd, 2) were found to be diradical complexes of a distorted tetrahedral geometry according to X‐band EPR spectroscopy. Tetrahedral structure of zinc complex 1 was confirmed by X‐ray diffraction analysis. The spectro‐ and electrochemistry of zinc complex 1 have been studied in details. For 1 a series of reversible one‐electron‐transfer waves leads to the formation of the anions and cations [M(L)2]2−,1−,1+,2+. All redox processes were shown to be ligand‐based. From variable temperature magnetic susceptibility measurements it has been established that at room temperature 1 possesses an S = 1 state with weak antiferromagnetic coupling between radical ligands (J = −41.4±0.4 cm−1) leading to an S = 0 ground state at low temperature.
Two‐Dimensional Layer‐Like Framework of Vanadate Clusters Bridged by [M(1,10‐phen)]2+: [M(1,10‐phen)(H2O)V2O6] (M = Fe, Zn)
Authors: Yu Li , Zhang Guoqian , Ma Pengtao , Li Suzhi , Niu Jingyang 
Published: May 2008

AbstractTwo organic‐inorganic hybrid vanadates [FeII(1,10‐phen)(H2O)V2O6] (1,10‐phen = 1,10‐phenanthroline) (1) and [Zn(1,10‐phen)(H2O)V2O6] (2) were synthesized hydrothermally and characterized by IR, TG, and single‐crystal X‐ray diffraction. The two compounds both crystallize in monoclinic P2(1)/c space group with a = 7.986Å, b = 21.4568Å, c = 9.5506Å, β = 112.5790(10)°, V = 1498.34(19) Å3 for 1 and a = 7.8655Å, b = 21.1761Å, c = 9.4726Å, β = 112.86(0)°, V = 1453.81(64) Å3 for 2. Single‐crystal X‐ray diffraction analysis show that the two compounds contain a one‐dimensional chain‐like vanadate cluster, which are bridged by [FeII(1,10‐phen)(H2O)]2+ or [Zn(1,10‐phen)(H2O)]2+ groups further forming in a two‐dimensional layer‐like framework.
Synthese, Kristallstrukturen und thermische Eigenschaften von Bariumsalzen der 4‐Sulfobenzoesäure
Authors: Wagner Christoph , Merzweiler Kurt 
Published: May 2008

AbstractSynthesis, Crystal Structures and Thermal Properties of Barium Salts of 4‐Sulfobenzoic AcidThe reaction of 4‐sulfobenzoic acid with barium hydroxide in the molar ratio 2 : 1 leads to the formation of Ba(O3SC6H4COOH)2 (1). 1·3H2O crystallizes triclinic, space group $\rm P{\bar 1}$, with a = 719.6(7), b = 1136.9(6), c = 1249.7(10) pm, α = 102.81(5), β = 91.73(7), γ = 106.95(6)° (at 293 K). The barium cations exhibit a ninefold coordination by six oxygen atoms from sulfonate and carboxyl groups and three water molecules. The linkage of the barium cations by bridging 4‐carboxybenzenesulfonate anions leads to a 3D coordination polymer. Ba(O3SC6H4COO) (2) is obtained from 4‐sulfobenzoic acid and barium hydroxide in equimolar amounts. 2·2H2O crystallizes monoclinic, space group C2/c with a = 2105.5(5), b = 704.1(1), c = 1455.4(3) pm, β = 90.49(3)° (at 220 K). The barium cations are coordinated by seven oxygen atoms from sulfonate and carboxylate groups and two water molecules. The 4‐sulfobenzoate anions act as bridging ligands to form a 3D coordination polymer.
Synthesis, Structure, and Characterization of Dichloro‐(1‐Benzyl‐4‐Acetato‐1,4,7‐Triazacyclononane)Iron(III)
Authors: Malkhasian Aramice Y. S. , Finch Maila E. , Pawlak Piotr L. , Anderson Jay M. , Brennessel William W. , Chavez Ferman A. 
Published: May 2008

AbstractThe synthesis, structure and aqueous solution behavior of [FeL1Cl2] (1, L1 = 1‐benzyl‐4‐acetato‐1,4,7‐triazacyclononane) is reported. The X‐ray structure of 1 reveals iron(III) in distorted octahedral geometry bonded to three amine nitrogen atoms and one carboxylate oxygen atom along with two cis chloride atoms. Electrochemical measurements of 1 in acetonitrile indicate that E1/2 = −200 mV vs Ag/AgCl. The stability of the +3 oxidation state is attributed to the hard Namine and carboxylate ligand donors. In acetonitrile, 1 is mononuclear and has an S = 5/2 spin state. The presence of a μ‐oxo bridge upon dissolution of 1 in water is supported by EPR and solution magnetic susceptibility NMR studies. pH‐metric titrations and UV‐vis studies indicate the presence of a total of four acidic protons. At low pH, L1(OH2)Fe‐O‐Fe(OH2)L1 is proposed to be stabilized while at high pH, L1(OH)Fe‐O‐Fe(OH)L1 is suggested to persist.
The Bis‐{Co2(μ‐dppm)(CO)4} Adduct of Dimethyl hex‐3‐en‐1,5‐diyne‐1,6‐dicarboxylate
Authors: Bruce Michael I. , Skelton Brian W. , White Allan H. , Zaitseva Natasha N. 
Published: May 2008

AbstractThe synthesis and structural characterization of a bis‐dicobalt derivative of dimethyl hex‐3‐en‐1,5‐diyne‐1,6‐dicarboxylate, [{Co2(μ‐dppm)(CO)4}2(μ:μ‐MeO2CC2CH=CHC2CO2Me)]·2CHCl3 (1) is described, permitting, in the context of previous related studies, comparison of the effects of progressive substitution of the ethene hydrogen atoms by C≡C·SiMe3 groupings.
Substituent Effects on Ru3C2 Clusters: Structural Comparisons of Some μ3‐Arylethynyl triruthenium‐carbonyl Clusters, [Ru3(μ‐X)(μ3‐C2Ar)(Y2)(CO)7], X = H, or Au(PPh3), Y2 = μ‐dppm or (CO)2
Authors: Bruce Michael I. , Gaudio Maryka , Skelton Brian W. , Werth Anja , White Allan H. 
Published: May 2008

AbstractComplexes of the form [Ru3(μ‐H)(μ3‐C2X)(μ‐dppm)(CO)7] have been widely characterized structurally for diverse R = H, tBu, CMePh(OH), CPhCH2, C5H7, C5H6Me, C6F5, as well as being studied theoretically. The R = Ph derivative was found to be isotypic with its C6F5 analogue, presenting an unusual opportunity for a comparative structural study, both structures being (re‐)determined at ‘low’‐temperature, whereupon the unit cell of the Ph derivative was found to double. The structure of [AuRu3(μ‐C2C6F5)(CO)9(PPh3)] is also recorded.
Sodium Pentafluorobenzoate Monohydrate: a Novel Two‐dimensional Carboxylate Polymer with Strong Sodium‐Fluorine Interactions
Authors: Bruce Michael I. , Hall Benjamin C. , Skelton Brian W. , White Allan H. 
Published: May 2008

AbstractSodium pentafluorobenzoate monohydrate, Na+[C6F5CO2]−·H2O crystallizes with two such formula units in the asymmetric unit of a monoclinic P21 lattice. It forms a novel two‐dimensional array based on Na2O2 rhombs, which combine sequentially in one dimension to generate a ‘cubanoid stair’ structure, in the network of which ‘chair’, ‘open cubane’, and other derivative motives may be discerned, and in which unusual Na···F interactions feature.
Synthesis and Characterization of Two Linear Fe‐M‐S Clusters Coordinated by Bis(pyrid‐2‐ylmethyl)amine(BPA): [(BPA)(DMF)FeS2MS2] (M = Mo, W)
Authors: Zhang Chun‐Xia , Ma Cheng‐Bing , Zhang Yue , Hu Ming‐Qiang , Chen Chang‐Neng , Liu Qiu‐Tian 
Published: May 2008

AbstractTwo heterometallic linear clusters [(BPA)Fe(DMF)S2MoS2] (1), and [(BPA)Fe(DMF)S2WS2] (2) have been synthesized and characterized by X‐ray crystallography and infrared spectra. X‐ray crystallography reveals that they are isostructural with each other. The iron atoms are six coordinated in distorted octahedral N3S2O coordination. The bond lengths of Fe‐Mo [2.8441(7) Å] and Fe‐W [2.8767(10) Å] are longer than normal values in Fe‐M‐S clusters containing the FeS2MoS2 core. The obviously long Fe‐O bond lengths in 1 and 2 indicate loose coordination for DMF ligands. There exist oppositely aligned dimers bridged by intermolecular S···S interactions in both two crystal structures, which relinked by N–H···S and C–H···S hydrogen bonding interactions into layers, π‐π stacking interactions provide the linkage between neighbouring layers, giving rise to the whole crystal structures.
Xenon as a Mediator of Chemical Reactions? Case of Elusive Gold Monofluoride, AuF, and its Adduct with Xenon, XeAuF
Authors: Kurzydłowski Dominik , Grochala Wojciech 
Published: May 2008

AbstractWe show, using Density Functional Theory calculations, that the phase diagram at T = 0 K of the 2/3 Au0 + 1/3 AuIIIF3 mixture is greatly affected by the presence of elemental xenon. The formation of a quasimolecular Xe→AuIF adduct is expected at 16 GPa, if not precluded by a partial oxidation of Xe at pressures exceeding 7.5 GPa. The Xe→AuIF adduct should yield Xe and AuIF upon careful decompression at 14 GPa. This contrasts with the behaviour of a pure (2/3 Au, 1/3 AuF3) mixture, investigated by us recently, where direct synthesis of AuIF via a comproportionation reaction is expected at substantially larger pressures (23 GPa). Presence of Xe thus facilitates the formation reaction by decreasing the required formation pressure by about one third.The most stable detected polymorph of Xe→AuIF is monoclinic (P21/m) and it exhibits interesting features of the electronic band structure.
Supramolecular Assemblies Formed by Cooperative Metal Coordination and Dimerization of the N‐(2‐pyrimidyl)‐N′‐(3‐pyridyl)urea Ligand via Hydrogen Bonding
Authors: Jia Chuandong , Liang Jianjun , Yang Jin , Huang Xiaojuan , Yang Xiao‐Juan , Wu Biao , Tang Ning 
Published: May 2008

AbstractThe supramolecular structures of two metal complexes, [CoCl2L2] (1) and [ZnCl2L2] (2), where L = N‐(2‐pyrimidyl)‐N′‐(3‐pyridyl)urea, are reported. The complexes feature zigzag chains formed by the self‐dimerization of the ligand via a pair of Nurea–H···Npyrimidyl hydrogen bonds with the $R \frac{2}{2}(8)$ motif. Only the pyridyl nitrogen atom coordinates to the metal atom whereas the two pyrimidyl N donors are involved in intra‐ and intermolecular hydrogen bonding interactions. The coordinated Cl atoms do not form any hydrogen bonds with the urea NH groups. The dimerization of the ligand (K = 90 M−1) was investigated by 1H NMR spectroscopy.