bluuebunny/crossref_metadata_2025_split huggingface dataset:
Exploring resonance theory and uncontrollability during co‐creative art making: A qualitative study among cancer patients
Authors: Weeseman Yvonne , Scherer‐Rath Michael , Christophe Nirav , Dörr Henny , Helmich Esther , Sprangers Mirjam A. G. , van Poecke Niels , van Laarhoven Hanneke W. M. 
Published: March 2024

AbstractPurposeCo‐creation, characterised by artists and patients creating a joint work of art, may support patients with the integration of life events, such as living with cancer, into their life story. In the process of co‐creation, resonance relationships between patients, artists and material may evolve that support such integration. Using the framework of resonance theory, we aim to investigate if and how patients move through the three phases of resonance during a process of co‐creation and explore the role of uncontrollability in this process.MethodsTen patients who received cancer treatment with palliative intent completed co‐creation processes, which were audio recorded. These recordings were imported in Atlas‐Ti and analysed by applying content analysis. We searched for the three phases of resonance, Being affected, touched and moved; Self‐efficacy and responding; Adaptive transformation. We additionally searched for signs of uncontrollability.ResultsPatients used 4–8 sessions (median 5 sessions) with a duration 90–240 min per session (median duration 120 min). We found that patients move through the three phases of resonance during co‐creation processes. Uncontrollability both presents a challenge and an invitation to integrate experiences of contingency into one's life narrative. Patients express self‐recognition and the experience of contingency in their work of art.ConclusionsIntegration of experiences of contingency into a life narrative can be supported by the process of co‐creation of art, which invites patients to relate to their illness, their environment and themselves. The phases of resonance in combination with uncontrollability as a continuously present factor, provide a means to both study and support the integration of experiences of contingency into the life narrative.
Exosomal miR‐1470 is a diagnostic biomarker and promotes cell proliferation and metastasis in colorectal cancer
Authors: Wu Yawen , Zhang Jie , Lin Fanfeng , Zhao Yajing , Zheng Baibing , Zhou Na , Zhang Zhe , Li Guanghao , Xie Li 
Published: March 2024

AbstractBackgroundIn recent years,the lack of specific markers for the diagnosis of colorectal cancer has led to an upward trend in both morbidity and mortality from this condition. There is an urgent need to identify molecular biomarkers that contribute to early cancer detection. This study aimed to identify specific exosomal microRNAs that hold potential as diagnostic biomarkers for CRC.MethodsWe screened for differentially expressed miRNAs using the CRC exosome dataset GSE39833. To validate the results in the public database, we collected serum from 168 CRC patients and 168 healthy volunteers. The expression levels of exosomal miR‐1470 in healthy volunteers and CRC patients were analyzed using qRT‐PCR. To evaluate the diagnostic potential of the selected miR‐1470 in distinguishing CRC patients from healthy controls, we analyzed its receiver operating characteristic curve. To explore the biological functions of miR‐1470 in CRC cell lines, we detected the miR‐1470's ability to regulate the growth and metastasis of CRC cells by CCK8, transwell and other assays after transfection of miR‐1470 in SW480, HCT‐116 cells.ResultsExosomal miR‐1470 exhibited significant up‐regulation in CRC patients compared to healthy volunteers. The ROC curve analysis revealed an area under the curve (AUC) of 0.74 (95% confidence interval: 0.6876–0.7920) for exosomal miR‐1470, indicating its potential as a diagnostic biomarker. Furthermore, the expression level of miR‐1470 in CRC patients showed correlations with age, metastasis, and HDL content. We overexpressed miR‐1470 in CRC cell lines. CCK8 proliferation assay showed that miR‐1470 promoted the proliferation ability of SW480 and HCT‐116 cells. Transwell assay showed that miR‐1470 promoted the migration and invasion ability of SW480 and HCT‐116 cells.ConclusionThis suggested that non‐invasive diagnosis of CRC is possible by detecting the level of miR‐1470 in exosomes, which has important implications for early detection and treatment of this disease.
Comparison of the multiples of the median of serum anti‐müllerian hormone and pregnancy outcomes in patients with gestational trophoblastic disease: A case–control study
Authors: Lai Theodora Hei Tung , Lau Lesley Suk Kwan , Ngu Siew Fei , Chu Man Yee Mandy , Chan Karen Kar Loen , Ng Ernest Hung Yu , Ngan Hextan Yuen Sheung , Li Raymond Hang Wun , Tse Ka Yu 
Published: March 2024

AbstractIntroductionChemotherapy is crucial in treating gestational trophoblastic neoplasia (GTN), but its impact on gonadotoxicity is unclear.Materials and MethodsThis case–control study included 57 GTN patients and 19 age‐matched patients with molar pregnancies (MP) in 2012–2018. Multiples of the median (MoM) of the serum AMH levels were compared between the two groups, and between patients using single‐agent and combination chemotherapy, at baseline, 6, 12, and 24 months after treatment. Their pregnancy outcomes were also compared.ResultsThere was no significant difference in the MoM of serum AMH between GTN and MP groups at all time points. Single‐agent chemotherapy did not adversely affect the MoM. However, those receiving combination chemotherapy had lower MoM than those receiving single‐agent chemotherapy at all time points. The trend of decline from the baseline was marginally significant in patients with combination chemotherapy, but the drop was only significant at 12 months (Z = −2.69, p = 0.007) but not at 24 months (Z = −1.90; p = 0.058). Multivariable analysis revealed that combination chemotherapy did not affect the MoM. There was no significant difference in the 4‐year pregnancy rate and the livebirth rate between the single‐agent and combination groups who attempting pregnancy, but it took 1 year longer to achieve the first pregnancy in the combination group compared to the single‐agent group (2.88 vs. 1.88 years).ConclusionThis study showed combination chemotherapy led to a decreasing trend of MoM of serum AMH especially at 12 months after treatment, but the drop became static at 24 months. Although pregnancy is achievable, thorough counseling is still needed in this group especially those wish to achieve pregnancy 1–2 years after treatment or with other risk factors.
Understanding the effectiveness of influencer recommendation information on social media platforms
Authors: Wang Fei , Zhang Chang , Lin Feiyan , Chi Maomao , Zhao Jing 
Published: March 2024

AbstractExisting social media influencer marketing research mainly explores how to enhance followers purchase intentions through the mechanisms of improving the follower–influencer relationship, however leaves research gaps regarding how to design effective influencer recommendation information (IRI) to stimulate consumer purchase behaviors. To address the gaps, a research model was established based on the information adoption model. This study collected 2276 influencer recommendation posts from typical Chinese social media influencer marketing platform WeChat Shopping Circle. Text‐mining methods were used to develop measurements from influencer posts, and survey data were collected from 20 participants from a large Chinese university to validate measurements. Using negative binomial regression, the empirical study found that the number of consumers who purchase recommended products is determined by the usefulness of IRI, whereby being further affected by content expertise, content novelty, and platform endorsement to influencers. The type of recommended products moderates the relationship between these influencing factors and information usefulness. This study makes contributions by revealing the informational influence mechanism of IRI and identifying what factors can exert effective informational influence for different types of products. It also offers practical implications for the design of influencer recommendation strategies.
New Hydroxyphenylacetic Acids and α‐Pyrone Derivative from the Deep‐Sea Cold Seep Sediment‐Derived Fungus Penicillium corylophilum CS‐682
Authors: Zhu Chi‐Sheng , Li Xiao‐Ming , Yang Sui‐Qun , Liu Yi‐Wei , Wang Bin‐Gui , Li Xin 
Published: March 2024

AbstractTwo pairs of new enantiomeric hydroxyphenylacetic acid derivatives, (±)‐corylophenols A and B ((±)‐1 and (±)‐2), a new α‐pyrone analogue, corylopyrone A (3), and six andrastin‐type meroterpenoids (4–9) were isolated and identified from the deep‐sea cold‐seep sediment‐derived fungus Penicillium corylophilum CS‐682. Their structures and stereo configurations were determined by detailed spectroscopic analysis of NMR and MS data, chiral HPLC analysis, J‐based configuration analysis, and quantum chemical calculations of ECD, specific rotation, and NMR (with DP4+ probability analysis). Compound 3 showed inhibitory activity against some strains of pathogenic bacteria.
Balloon rupture during transcatheter aortic valve replacement
Authors: Basman Craig , Landers David , Kliger Chad , Rodriguez‐Barragan Karla , Yoon Sung‐Han , Faraz Haroon , Patel Ankitkumar , Dudiy Yuriy , Anderson Mark , Kaple Ryan 
Published: March 2024

AbstractA distinctive complication with balloon‐expandable (BE) THV platforms such as the Edwards Sapien (Edwards Lifescience) is the possibility of balloon rupture during THV deployment. Balloon rupture is a rare occurrence that can result in stroke due to fragment embolism, incomplete THV expansion, and/or vascular injury upon retrieval of the balloon. Careful evaluation of preoperative computed tomography is essential to identify high‐risk cases. While annular and left ventricular outflow tract (LVOT) calcification are widely acknowledged as common risks for balloon injury, it's essential to note that balloon injury can manifest at various anatomical sites. In this review, we discuss the mechanism behind balloon rupture, methods to identify cases at a heightened risk of balloon injury, approaches to mitigate the risk of rupture, and percutaneous retrieval strategies.
Scalable Bioreactor Production of an O2‐Protected [FeFe]‐Hydrogenase Enables Simple Aerobic Handling for Clean Chemical Synthesis
Authors: Cleary Sarah E. , Hall Stephen J. , Galan‐Bataller Regina , Lurshay Tara C. , Hancox Charlotte , Williamson James J. , Heap John T. , Reeve Holly A. , Morra Simone 
Published: March 2024

AbstractThe enzyme CbA5H, a [FeFe]‐hydrogenase from Clostridium beijerinckii, has previously been shown to survive exposure to oxygen, making it a promising candidate for biotechnological applications. Thus far [NiFe]‐hydrogenases are typically considered for such applications, due to the superior O2‐tolerance and therefore simplified enzyme handling. However, methods for production of [FeFe]‐hydrogenases are generally more successful than for other classes of hydrogenases, therefore in this work we focus on demonstrating scalable CbA5H production, and report results with active enzyme prepared in bioreactors (up to 10 L) with >20‐fold improvement in purified enzyme yield. We then go on to confirm excellent H2/H+‐cycling activity of the air‐purified protein, highlighting that CbA5H can be prepared and isolated without the need for complex and expensive infrastructure. Next, we demonstrate good stability of the air‐purified CbA5H both in solution assays, and as a heterogenous catalyst system when immobilized on a carbon support. Finally, we successfully implement this enzyme within previously demonstrated biotechnologies for flavin and NADH recycling, highlighting its relevance in chemical synthesis, and we demonstrate production of an important API precursor, 3‐quinuclidinol at >0.4 g scale in standard benchtop hydrogenation infrastructure, with >100,000 CbA5H turnovers over 18 operational hours.
Ultralow charge–discharge voltage gap of 0.05 V in sunlight‐responsive neutral aqueous Zn–air battery
Authors: Niu Zhimin , Gao Yan , Wu Tianhui , Zhang Fei , Zhao Ran , Chen Zijia , Yuan Yiming , Jiao Tifeng , Gu Jianmin , Lu Li , Wang Desong 
Published: March 2024

AbstractRechargeable neutral aqueous zinc−air batteries (ZABs) are a promising type of energy storage device with longer operating life and less corrosiveness compared with conventional alkaline ZABs. However, the neutral ZABs normally possess poor oxygen evolution reactions (OERs) and oxygen reduction reactions performance, resulting in a large charge–discharge voltage gap and low round‐trip efficiency. Herein, we demonstrate a sunlight‐assisted strategy for achieving an ultralow voltage gap of 0.05 V in neutral ZABs by using the FeOOH‐decorated BiVO4 (Fe‐BiVO4) as an oxygen catalyst. Under sunlight, the electrons move from the valence band (VB) of Fe‐BiVO4 to the conduction band producing holes in VB to promote the OER process and hence reduce the overpotential. Meanwhile, the photopotential generated by the Fe‐BiVO4 compensates a part of the charging potential of neutral ZABs. Accordingly, the energy loss of the battery could be compensated via solar energy, leading to a record‐low gap of 0.05 V between the charge and discharge voltage with a high round‐trip efficiency of 94%. This work offers a simple but efficient pathway for solar‐energy utilization in storage devices, further guiding the design of high energy efficiency of neutral aqueous ZABs.
Generation and Application of Aryl Radicals Under Photoinduced Conditions
Authors: Das Anupam , Justin Thomas K. R. 
Published: March 2024

AbstractPhotoinduced aryl radical generation is a powerful strategy in organic synthesis that facilitates the formation of diverse carbon‐carbon and carbon‐heteroatom bonds. The synthetic applications of photoinduced aryl radical formation in the synthesis of complex organic compounds, including natural products, physiologically significant molecules, and functional materials, have received immense attention. An overview of current developments in photoinduced aryl radical production methods and their uses in organic synthesis is given in this article. A generalized idea of how to choose the reagents and approach for the generation of aryl radicals is described, along with photoinduced techniques and associated mechanistic insights. Overall, this article offers a critical assessment of the mechanistic results as well as the selection of reaction parameters for specific reagents in the context of radical cascades, cross‐coupling reactions, aryl radical functionalization, and selective C−H functionalization of aryl substrates.
Theoretical relationships between axoneme distortion and internal forces and torques in ciliary beating
Authors: Woodhams Louis G. , Bayly Philip V. 
Published: March 2024

AbstractThe axoneme is an intricate nanomachine responsible for generating the propulsive oscillations of cilia and flagella in an astonishing variety of organisms. New imaging techniques based on cryoelectron‐tomography (cryo‐ET) and subtomogram averaging have revealed the detailed structures of the axoneme and its components with sub‐nm resolution, but the mechanical function of each component and how the assembly generates oscillations remains stubbornly unclear. Most explanations of oscillatory behavior rely on the dynamic regulation of dynein by some signal, but this may not be necessary if the system of dynein‐driven slender filaments is dynamically unstable. Understanding the possibility of instability‐driven oscillations requires a multifilament model of the axoneme that accounts for distortions of the axoneme as it bends. Active bending requires forces and bending moments that will tend to change the spacing and alignment of doublets. We hypothesize that components of the axoneme resist and respond to these loads in ways that are critical to beating. Specifically, we propose (i) that radial spokes provide torsional stiffness by resisting misalignment (as well as spacing) between the central pair and outer doublets, and (ii) that the kinematics of dynein arms affect the relationships between active forces and bending moments on deforming doublets. These proposed relationships enhance the ability of theoretical, multifilament models of axonemal beating to generate propulsive oscillatory waveforms via dynamic mechanical instability.
Social network centrality and the corporate environment: The case of sexual diversity policies
Authors: Nundhapana Nuttavuth , Chiyachantana Chiraphol N. , Ding David K. , Treepongkaruna Sirimon 
Published: March 2024

AbstractWe study the external influence of social capital, measured by Facebook's (now Meta) Social Connectedness Index, on a firm's decision to adopt policies that promote a more diverse corporate environment. Recent studies find corporate policies that embrace sexual diversity are beneficial to firms and their stakeholders, thereby contributing to their corporate social responsibility (CSR) and business sustainability. We find that firms with a high social network centrality are more likely to adopt policies and business strategies that support sexual diversity. Moreover, firms that adopt good CSR practices are more likely to implement more inclusive policies such as sexual diversity policies. This provides for a more comfortable work environment for the LGBT+ community. However, we also find that firms reduce their adoption of inclusive policies during times of economic uncertainty, supporting the pessimistic view that firms decrease window dressing activities during economic downturns when governance is tightened, and resources are scarce. We attribute this phenomenon to the exploitation of agency benefits by managers.
Photoelectrochemical Lithium Extraction from Waste Batteries
Authors: Lyu Yanhong , Zheng Jianyun , Wang Shuangyin 
Published: March 2024

AbstractThe amount of global hybrid‐electric and all electric vehicle has increased dramatically in just five years and reached an all‐time high of over 10 million units in 2022. A good deal of waste lithium (Li)‐containing batteries from dead vehicles are invaluable unconventional resources with high usage of Li. However, the recycle of Li by green approaches is extremely inefficient and rare from waste batteries, giving rise to severe environmental pollutions and huge squandering of resources. Thus, in this mini review, we briefly summarized a green and promising route‐photoelectrochemical (PEC) technology for extracting the Li from the waste lithium‐containing batteries. This review first focuses on the critical factors of PEC performance, including light harvesting, charge‐carrier dynamics, and surface chemical reactions. Subsequently, the conventional and PEC technologies applying in the area of Li recovery processes are analyzed and discussed in depth, and the potential challenges and future perspective for rational and healthy development of PEC Li extraction are provided positively.
Understanding and Controlling Electrostatic Discharge in Triboelectric Nanogenerators
Authors: Leon Ronald T. , Sherrell Peter C. , Michel Jesus Ibarra , Bullock James , Berry Joseph D. , Ellis Amanda V. 
Published: March 2024

AbstractTriboelectric nanogenerators (TENGs) have been widely used to harness various forms of mechanical energy for conversion to electrical energy. However, the contentious challenge in characterising TENGs is the lack of standard protocols for assessing mechanical‐to‐electrical energy conversion processes. Herein, macroscopic signal analysis is used to identify three key charging events within triboelectric signals: charge induction (CI), contact electrification (CE), and electrostatic discharge (ESD). By considering two phases of motion during contact‐separation (approach and departure of the contact materials), CI arising from the motion of bound surface charge (varying electric field) between opposing contact materials is shown to dominate the measured displacement current signal, rather than the process of CE itself. Furthermore, the conventional signal (i. e., voltage, current, charge) interpretation of CE and CI during approach and departure phases is re‐assessed, to indicate that the sudden spike of current often observed immediately prior to contact (or after separation) arises from polarity inverting electrostatic discharge (ESD). This aspect of the measured triboelectric effect, which is often ignored, is crucial for the design of TENGs and hence, techniques to enhance the understanding and control over the stochastic occurrence of ESDs is explored. The methods proposed for the deconvolution of the macroscopic signal components of TENGs, and mitigation of ESD occurrences, will allow for precise quantification of the associated charging events. The applications of this study will template the design and development of future super‐TENGs with optimised energy conversion capabilities.
Wastewater surveillance to assess cocaine and methylenedioxymethamphetamine use trends during a major music festival in Brazil
Authors: Gomes Cezar Silvino , de Jesus Soares Freire Diogo , de Souza Ramos Pontes Moura Hadassa , Maldaner Adriano Otávio , Pinheiro Francisco Ayrton Senna Domingos , Ferreira George Leandro Ramos , de Oliveira Miranda Matheus Leopoldo , Ferreira Leandro De Santis , Murga Felipe Gonçalves , Sodré Fernando Fabriz , Aragão Cícero Flávio Soares 
Published: March 2024

AbstractThis study employed the wastewater‐based epidemiology (WBE) strategy to investigate cocaine (COC) and ecstasy (MDMA) usage during Carnatal festival in Rio Grande do Norte, Brazil. Wastewater samples were collected over the four festival days (December 12–15, 2019), as well as during corresponding days before and after the event. The samples underwent filtration, acidification, solid‐phase extraction (SPE) for pre‐concentration, and analysis using ultra‐high‐performance liquid chromatography–tandem mass spectrometry (UHPLC–MS/MS) with calibration using deuterated internal standards. The measured concentration ranges in the wastewater samples were as follows: benzoylecgonine (BE, a metabolite of COC use) ranged from 760 ± 30 to 8914 ± 252 ng/L, COC (non‐metabolized or directly discharged) ranged from 1182 ± 25 to 6,760 ± 95 ng/L, cocaethylene (COE, a metabolite of alcohol‐COC use) ranged from 21 ± 10 to 161 ± 10 ng/L, and MDMA (ecstasy) ranged from 18 ± 5 to 613 ± 15 ng/L. Daily wastewater loads were estimated as 0.81 ± 0.03 to 11.69 ± 0.33 g/day for BE, 1.42 ± 0.03 to 8.06 ± 0.11 g/day for COC, 0.02 ± 0.01 to 0.21 ± 0.01 g/day for COE, and 0.02 ± 0.01 to 0.80 ± 0.02 g/day for MDMA. Notably, COE and MDMA were only detected above the quantification limit during the festival days. The data enable estimating that COC consumption doubled during the event days. The COC/BE ratio indicated likely drug disposals on the event's last day and the subsequent week. The study's findings shed light on illicit substance consumption, assisting in public health programs and combating drug trafficking efforts.