bluuebunny/crossref_metadata_2025_split huggingface dataset:
Limiting Distribution of Dense Orbits in a Moduli Space of Rank m Discrete Subgroups in (m+1)-Space
Authors: Bersudsky Michael , Xing Hao 
Published: April 2024

Abstract
We study the limiting distribution of dense orbits of a lattice subgroup $\Gamma \leq \textrm{SL}(m+1,\mathbb{R})$ acting on $H\backslash \textrm{SL}(m+1,\mathbb{R})$, with respect to a filtration of growing norm balls. The novelty of our work is that the groups $H$ we consider have infinitely many non-trivial connected components. For a specific such $H$, the homogeneous space $H\backslash G$ identifies with $X_{m,m+1}$, a moduli space of rank $m$-discrete subgroups in $\mathbb{R}^{m+1}$. This study is motivated by the work of Shapira-Sargent who studied random walks on $X_{2,3}$.
Analyte Extension Method Validation of Elemental Analysis Manual Method 4.7 for Six Additional Elements, Cobalt (Co), Strontium (Sr), Thallium (Tl), Tin (Sn), Uranium (U), and Vanadium (V)
Authors: Kovalenko Anthony , Stutts Dominique , Gray Patrick J 
Published: April 2024

Abstract

Background
An interlaboratory study was conducted at the U.S. Food and Drug Administration’s (FDA) Northeast Food and Feed Laboratory (NFFL) and the Center for Food Safety and Applied Nutrition (CFSAN) with the purpose to expand FDA Elemental Analysis Manual (EAM) method 4.7 (Inductively Coupled Plasma-Mass Spectrometric Determination of Arsenic, Cadmium, Chromium, Lead, Mercury, and Other Elements in Food Using Microwave Assisted Digestion) to include new analytes.

Objective
The goal of the study was to demonstrate the performance of FDA EAM method 4.7 when analyzing new analytes cobalt (Co), strontium (Sr), thallium (Tl), tin (Sn), uranium (U), and vanadium (V). This analyte extension method validation of EAM 4.7 for six additional elements, Co, Sr, Tl, Sn, U, and V, followed all guidelines for a Level 2 or single-laboratory validation and met all acceptance criteria for analyte extensions as per the Guidelines for the Validation of Chemical Methods.

Method
As per EAM 4.7, this study followed the procedures and used specified equipment operated under recommended conditions. The analyte extension method validation was performed in accordance with protocol and with no deviations.

Results
All quality control (QC) requirements for this analyte extension method validation of EAM 4.7 passed as evidenced by the analytical data. The results presented demonstrate accuracy, linearity, and precision by successful analyses of method blanks, matrix spikes, unfortified test samples, and reference materials. The data analyzed met each of the validation requirements for each analyte in all representative matrixes.

Conclusions
The study showed that the new analytes performed satisfactorily using EAM 4.7 for total acidic extractable elemental analysis of food according to FDA’s guidelines.

Highlights
The method met or exceeded the performance criteria.
Challenges in the surgical treatment and management of the patient with super super obesity
Authors: Ducas Alvaro , Lopez Paula , Figueroa Beatriz , Manueli Laos Emiliano G , Mangano Alberto , Hassan Chandra 
Published: April 2024

Abstract
Obesity is defined by the Body Mass Index (BMI) which is derived by the weight and height of a person (BMI &gt; 30). Furthermore, obesity is classified as super-obesity (BMI &gt;50 kg/m2) and super-super obesity (BMI &gt;60 kg/m2) by the International Bariatric Surgery Registry (Renquist K. Obesity classification. Obes Surg 1997;7:523). Patients with super-super obesity have a greater incidence of comorbid diseases and are at greater risk of postoperative morbidity and mortality and longer length of hospital stay (LOS). Soong et al. described short-term outcomes after weight loss surgery comparing a group of patients with super-obesity with another group of patients with super-super obesity. The authors concluded that experienced surgeons could achieve comparable outcomes in both groups. However, higher BMI is associated with longer operative time, longer LOS, and delayed discharge to chronic care facilities (Soong TC, Lee MH, Lee WJ, et al. Long-term efficacy of bariatric surgery for the treatment of super-obesity: comparison of SG, RYGB, and OAGB. Obes Surg. 2021;31:3391–99. https://doi.org/10.1007/s11695-021-05464-0). The following paradigmatic case report aims at showing the complex management of a patient with super-super obesity, with BMI of 141.2 kg/m2 and associated multiple comorbidities.
A case of non-bacterial thrombotic endocarditis on the aortic valve following coronary angiography
Authors: Motiduki Nobuhiro , Ushioda Ryohei , Yuzawa Sayaka , Miyatani Kazuki , Isa Hideki , Setogawa Yuki , Ishidou Kohei , Narita Masahiko , Suzuki Fumitaka , Hirofuji Aina , Okubo Ryo , Kunioka Shingo , Tsutsui Masahiro , Ishikawa Natsuya , Hiroyuki Kamiya 
Published: April 2024

Abstract
Nonbacterial thrombotic endocarditis (NBTE) on the aortic valve involves fibrin and platelet aggregate formation, potentially leading to embolic events. We present a case of NBTE on the aortic valve following coronary angiography (CAG) in a 54-year-old man with multiple comorbidities. Surgical thrombectomy was performed owing to acute cerebral infarcts. This case highlights the significance of considering that mechanical trauma from catheterization during CAG can trigger thrombus formation.
Finding common features in multilingual fake news: a quantitative clustering approach
Authors: Yuan Wei , Liu Haitao 
Published: April 2024

Abstract
Since the Internet is a breeding ground for unconfirmed fake news, its automatic detection and clustering studies have become crucial. Most current studies focus on English texts, and the common features of multilingual fake news are not sufficiently studied. Therefore, this article uses English, Russian, and Chinese as examples and focuses on identifying the common quantitative features of fake news in different languages at the word, sentence, readability, and sentiment levels. These features are then utilized in principal component analysis, K-means clustering, hierarchical clustering, and two-step clustering experiments, which achieved satisfactory results. The common features we proposed play a greater role in achieving automatic cross-lingual clustering than the features proposed in previous studies. Simultaneously, we discovered a trend toward linguistic simplification and economy in fake news. Furthermore, fake news is easier to understand and uses negative emotional expressions in ways that real news does not. Our research provides new reference features for fake news detection tasks and facilitates research into their linguistic characteristics.
The dependence of assembly bias on the cosmic web
Authors: Montero-Dorta Antonio D , Rodriguez Facundo 
Published: April 2024

ABSTRACT
For low-mass haloes (i.e. Mhalo ≲ 1013 h−1 M⊙), the physical origins of halo assembly bias have been linked to the slowdown of accretion due to tidal forces, which are more dominant in some cosmic-web environments as compared to others. Here, we use publicly available data from the application of the Discrete Persistent Structures Extractor (DisPerSE) to the IllustrisTNG magnetohydrodynamical simulation to investigate the dependence of the related galaxy assembly bias effect on the cosmic web. We show that, at fixed halo mass, the galaxy population displays significant secondary bias when split by distance to DisPerSE critical points representing nodes (dnode), filaments (dskel), and saddles (dsadd), with objects closer to these features being more tightly clustered (particularly at Mhalo ≲ 1012.5 h−1 M⊙). The secondary bias produced by some of these parameters exceeds the assembly bias signal considerably at some mass ranges, especially for dsadd. We also demonstrate that the assembly bias signal is reduced significantly when clustering is conditioned to galaxies being close or far from these critical points. The maximum attenuation is measured for galaxies close to saddle points, where less than 35 per cent of the signal remains. Objects near voids, conversely, preserve a fairly pristine signal (almost 85 per cent). Our analysis confirms the importance of the tidal field in shaping assembly bias, but it is also consistent with the signal being the result of different physical mechanisms. Our work introduces new aspects of secondary bias where predictions from simulations can be directly tested with observational data.
Unveiling energy pathways in AGN accretion flows with the warm corona model for the soft excess
Authors: Ballantyne D R , Sudhakar V , Fairfax D , Bianchi S , Czerny B , De Rosa A , De Marco B , Middei R , Palit B , Petrucci P -O , Różańska A , Ursini F 
Published: April 2024

ABSTRACT
The soft excess in active galactic nuclei (AGNs) may arise through a combination of relativistic reflection and the effects of a warm corona at the surface of the accretion disc. Detailed examination of the soft excess can therefore constrain models of the transport and dissipation of accretion energy. Here, we analyse 34 XMM–Newton observations from 14 type 1 AGNs with the reXcor spectral model that self-consistently combines emission from a warm corona with relativistic reflection assuming a lamppost corona. The model divides accretion energy between the disc, the warm corona, and the lamppost. The XMM–Newton observations span a factor of 188 in Eddington ratio (λobs) and 350 in black hole mass, and we find that a warm corona is a significant contributor to the soft excess for 13 of the 14 AGNs with a mean warm corona heating fraction of 0.51. The reXcor fits reveal that the fraction of accretion energy dissipated in the lamppost is anticorrelated with λobs. In contrast, the relationship between λobs and both the optical depth and the heating fraction of the warm corona appears to transition from an anticorrelation to a correlation at λobs,t ≈ 0.15. Therefore, at least one other physical process in addition to the accretion rate is needed to explain the evolution of the warm corona. Overall, we find that a warm corona appears to be a crucial depository of accretion energy in AGNs across a broad range of λobs and black hole mass.
The frequency of metal enrichment of cool helium-atmosphere white dwarfs using the DESI early data release
Authors: Manser Christopher J , Gänsicke Boris T , Izquierdo Paula , Swan Andrew , Najita Joan , Rockosi C , Carrillo Andreia , Kim Bokyoung , Xu Siyi , Dey Arjun , Aguilar J , Ahlen S , Blum R , Brooks D , Claybaugh T , Dawson K , de la Macorra A , Doel P , Gaztañaga E , Gontcho A Gontcho S , Honscheid K , Kehoe R , Kremin A , Landriau M , Le Guillou L , Levi Michael E , Li T S , Meisner A , Miquel R , Nie J , Rezaie M , Rossi G , Sanchez E , Schubnell M , Tarlé G , Weaver B A , Zhou Z , Zou H 
Published: April 2024

ABSTRACT
There is an overwhelming evidence that white dwarfs host planetary systems; revealed by the presence, disruption, and accretion of planetary bodies. A lower limit on the frequency of white dwarfs that host planetary material has been estimated to be ≃ 25–50 per cent; inferred from the ongoing or recent accretion of metals on to both hydrogen-atmosphere and warm helium-atmosphere white dwarfs. Now with the unbiased sample of white dwarfs observed by the Dark Energy Spectroscopic Instrument (DESI) survey in their Early Data Release (EDR), we have determined the frequency of metal enrichment around cool-helium atmosphere white dwarfs as 21 ± 3 per cent using a sample of 234 systems. This value is in good agreement with values determined from previous studies. With the current samples we cannot distinguish whether the frequency of planetary accretion varies with system age or host-star mass, but the DESI data release 1 will contain roughly an order of magnitude more white dwarfs than DESI EDR and will allow these parameters to be investigated.
Mitolnc controls cardiac BCAA metabolism and heart hypertrophy by allosteric activation of BCKDH
Authors: Weiss Maria , Hettrich Sara , Hofmann Theresa , Hachim Salma , Günther Stefan , Braun Thomas , Boettger Thomas 
Published: April 2024

Abstract
Enzyme activity is determined by various different mechanisms, including posttranslational modifications and allosteric regulation. Allosteric activators are often metabolites but other molecules serve similar functions. So far, examples of long non-coding RNAs (lncRNAs) acting as allosteric activators of enzyme activity are missing. Here, we describe the function of mitolnc in cardiomyocytes, a nuclear encoded long non-coding RNA, located in mitochondria and directly interacting with the branched-chain ketoacid dehydrogenase (BCKDH) complex to increase its activity. The BCKDH complex is critical for branched-chain amino acid catabolism (BCAAs). Inactivation of mitolnc in mice reduces BCKDH complex activity, resulting in accumulation of BCAAs in the heart and cardiac hypertrophy via enhanced mTOR signaling. We found that mitolnc allosterically activates the BCKDH complex, independent of phosphorylation. Mitolnc-mediated regulation of the BCKDH complex constitutes an important additional layer to regulate the BCKDH complex in a tissue-specific manner, evading direct coupling of BCAA metabolism to ACLY-dependent lipogenesis.
RecA-dependent or independent recombination of plasmid DNA generates a conflict with the host EcoKI immunity by launching restriction alleviation
Authors: Skutel Mikhail , Yanovskaya Daria , Demkina Alina , Shenfeld Aleksandr , Musharova Olga , Severinov Konstantin , Isaev Artem 
Published: April 2024

Abstract
Bacterial defence systems are tightly regulated to avoid autoimmunity. In Type I restriction–modification (R–M) systems, a specific mechanism called restriction alleviation (RA) controls the activity of the restriction module. In the case of the Escherichia coli Type I R–M system EcoKI, RA proceeds through ClpXP-mediated proteolysis of restriction complexes bound to non-methylated sites that appear after replication or reparation of host DNA. Here, we show that RA is also induced in the presence of plasmids carrying EcoKI recognition sites, a phenomenon we refer to as plasmid-induced RA. Further, we show that the anti-restriction behavior of plasmid-borne non-conjugative transposons such as Tn5053, previously attributed to their ardD loci, is due to plasmid-induced RA. Plasmids carrying both EcoKI and Chi sites induce RA in RecA- and RecBCD-dependent manner. However, inactivation of both RecA and RecBCD restores RA, indicating that there exists an alternative, RecA-independent, homologous recombination pathway that is blocked in the presence of RecBCD. Indeed, plasmid-induced RA in a RecBCD-deficient background does not depend on the presence of Chi sites. We propose that processing of random dsDNA breaks in plasmid DNA via homologous recombination generates non-methylated EcoKI sites, which attract EcoKI restriction complexes channeling them for ClpXP-mediated proteolysis.
Divergence in Cigarette Discontinuation Rates by Use of Electronic Nicotine Delivery Systems (ENDS): Longitudinal Findings From the United States PATH Study Waves 1–6
Authors: Kasza Karin A , Tang Zhiqun , Seo Young Sik , Benson Adam F , Creamer MeLisa R , Edwards Kathryn C , Everard Colm , Chang Joanne T , Cheng Yu-Ching , Das Babita , Oniyide Olusola , Tashakkori Nicole A , Weidner Anna-Sophie , Xiao Haijun , Stanton Cassandra , Kimmel Heather L , Compton Wilson , Hyland Andrew 
Published: April 2024

Abstract

Introduction
We compare real-world trends in population-level cigarette discontinuation rates among adults (ages ≥21) who smoked cigarettes, by electronic nicotine delivery systems (ENDS) use.

Aims and Methods
U.S nationally representative data from adults in the Population Assessment of Tobacco and Health (PATH) Study (2013/14-2021, Waves 1–6) who smoked cigarettes in the past 30 days (P30D) were analyzed (n = 13 640). The exposure was P30D ENDS use. The outcome was P30D cigarette discontinuation at biennial follow-up. Weighted trend analyses were conducted to test for differences in cigarette discontinuation trends by ENDS use.

Results
Between 2013/14 and 2015/16, cigarette discontinuation rates were both 16% for those who used ENDS and for those who did not; between 2018/19 and 2021, rates were ~30% for those who used ENDS and ~20% for those who did not; the time by ENDS use interaction was significant.

Conclusions
The relationship between adults’ ENDS use and cigarette discontinuation in the context of an expanded ENDS marketplace, new tobacco regulatory actions, and COVID-19 differs from the relationship in earlier years.

Implications
It is important for public health decisions to be informed by research based on the contemporary ENDS marketplace and circumstances.
The association between serum vitamin D levels and abnormal lipid profile in pediatrics: A GRADE-assessed systematic review and dose–response meta-analysis of epidemiologic studies
Authors: Hajhashemy Zahra , Tirani Shahnaz Amani , Askari Gholamreza , Saneei Parvane 
Published: April 2024

Abstract

Context
Several studies have investigated the relationship between serum vitamin D and dyslipidemia in children and adolescents, but the findings have been contradictory.

Objective
The current systematic review and dose–response meta-analysis investigated the serum vitamin D – dyslipidemia relationship in children and adolescents.

Data Sources
ISI Web of Science, Scopus, MEDLINE (PubMed), EMBASE databases, and Google Scholar, were searched up to December 2022.

Data Extraction
Observational studies that investigated the odds of dyslipidemia in categories of serum vitamin D levels in children were included, and their data were extracted.

Data Analysis
Pooling of 17 effect sizes from 15 studies (39 342 participants) showed that subjects with higher serum vitamin D had 27% lower odds of hypertriglyceridemia (odds ratio [OR] = 0.73; 95% confidence interval [CI]: 0.60, 0.88). A meta-analysis of 18 effect sizes from 16 studies (39 718 participants) illustrated that highest vs lowest serum vitamin D was related to 22% lower odds of low high-density lipoprotein cholesterol (HDL-c) (OR = 0.78; 95% CI: 0.66, 0.91). Also, a nonlinear association between serum vitamin D and odds of abnormal lipid profile was found: elevating values of 25-hydroxyvitamin D from 35 nmol/L to 55 nmol/L was associated with a decreasing trend in odds of hypertriglyceridemia, hyper low-density lipoprotein cholesterolemia, hypercholesterolemia, and hypo HDL-cholesterolemia. However, no significant linear association was observed. Based on the Grading of Recommendations, Assessment, Development and Evaluations (GRADE), the certainty of all evidence was rated as high.

Conclusion
This meta-analysis revealed that the level of 25-hydroxyvitamin D was inversely related to odds of abnormal serum triglycerides and HDL-c in children and adolescents. Increasing serum vitamin D from 35 nmol/L to 55 nmol/L was associated with a decreasing trend in the odds of abnormal serum triglycerides, HDL-c, low-density lipoprotein cholesterol, and total cholesterol in children.

Systematic Review Registration
PROSPERO registration no. 42023400787.
Dietary fat intake with risk of gestational diabetes mellitus and preeclampsia: a systematic review and meta-analysis of prospective cohort studies
Authors: Talebi Sepide , Zeraattalab-Motlagh Sheida , Rahimlou Mehran , Sadeghi Erfan , Rashedi Minoo Hasan , Ghoreishy Seyed Mojtaba , Mohammadi Hamed 
Published: April 2024

Abstract

Context
Gestational diabetes mellitus (GDM) and preeclampsia (PE) are commonly observed medical complications in pregnancy. Dietary total fat and fatty acids associated with GDM and PE risk have been examined in several epidemiological studies. In some instances, systematic reviews and meta-analyses might provide more accurate dietary recommendations.

Objectives
This systematic review and dose-response meta-analysis was conducted to investigate the association between dietary total fat and fatty acids and the risk of GDM and PE.

Data sources
Research on dietary fat intake and the risk of GDM and PE was conducted through systematic searches of the PubMed, Scopus, and Web of Science databases for articles published up to August 19, 2023. An investigation of associations between dietary intake of total fat and fatty acids and the risk of GDM and PE was performed using prospective cohort study designs.

Results
Twenty-one prospective cohort studies were considered eligible. Findings indicated that higher intakes of total fat (relative risk [RR], 1.08; 95% confidence interval [CI], 1.02–1.14), animal fat (RR, 1.56; 95%CI, 1.34–1.89), vegetable fat (RR, 1.23; 95%CI, 1.05–1.45), dietary cholesterol (RR, 1.48; 95%CI, 1.10–2.00), and omega-3 fatty acid (RR, 1.11; 95%CI, 1.02–1.20) are associated with a greater risk of GDM. However, no significant association was found between dietary total fat and fatty acids and the risk of PE. Dose-response meta-analyses suggested every 10% increment in total energy intake from total fat, 5% from animal fat, 5% from vegetable fat, and 100 mg from cholesterol was related to 15%, 12%, 7%, 14%, and 20% higher GDM risk, respectively.

Conclusions
Overall, total fat, animal fat, vegetable fat, dietary cholesterol, and omega-3 fatty acid consumption are associated with a small but statistically significant increase in GDM risk.

Protocol Registration
PROSPERO (CRD42023466844).
Shareholder-Creditor Conflict and the Resolution of Financial Distress
Authors: Chu Yongqiang , Diep-Nguyen Ha , Wang Jun , Wang Wei , Wang Wenyu 
Published: April 2024

Abstract
Constructing a comprehensive data set of financially distressed firms that restructured their debts from 2000–2014, we find that firms with financial institutions’ loan-equity simultaneous holdings are more likely to restructure out of court than to file for bankruptcy. The effect is stronger when loans are oversecured and when the expected bankruptcy costs are larger. We use mergers of financial institutions and instrumental variable estimations to address potential endogeneity concerns. Firms with simultaneous holdings experience higher stock returns. The evidence suggests that mitigating shareholder-creditor conflict results in cost-effective resolutions of financial distress.