bluuebunny/crossref_metadata_2025_split huggingface dataset:
Prevalence and outcomes of polycystic kidney disease in African populations: A systematic review
Authors: Ndongo Modou , Nehemie Lot Motoula , Coundoul Baratou , Diouara Abou Abdallah Malick , Seck Sidy Mohamed 
Published: March 2024

BACKGROUND
Polycystic kidney disease (PKD) is the most common genetic cause of kidney disease. It is a progressive and irreversible condition that can lead to end-stage renal disease and many other visceral complications. Current comprehensive data on PKD patterns in Africa is lacking.
AIM
To describe the prevalence and outcomes of PKD in the African population.
METHODS
A literature search of PubMed, African journal online, and Google Scholar databases between 2000 and 2023 was performed. The Preferred Reporting Items for Systematic Reviews and Meta-Analyses were followed to design the study. Clinical presentations and outcomes of patients were extracted from the included studies.
RESULTS
Out of 106 articles, we included 13 studies from 7 African countries. Ten of them were retrospective descriptive studies concerning 943 PKD patients with a mean age of 47.9 years. The accurate prevalence and incidence of PKD were not known but it represented the third causal nephropathy among dialysis patients. In majority of patients, the diagnosis of the disease was often delayed. Kidney function impairment, abdominal mass, and hypertension were the leading symptoms at presentation with a pooled prevalence of 72.1% (69.1–75.1), 65.8% (62.2–69.4), and 57.4% (54.2–60.6) respectively. Hematuria and infections were the most frequent complications. Genotyping was performed in few studies that revealed a high proportion of new mutations mainly in the PKD1 gene.
CONCLUSION
The prevalence of PKD in African populations is not clearly defined. Clinical symptoms were almost present with most patients who had kidney function impairment and abdominal mass at the diagnostic. Larger studies including genetic testing are needed to determine the burden of PKD in African populations.
Analisis Laik Fungsi Jl. K.H. Hasyim Ashari Sampai Jl. Gatot Subroto
Authors: Muhammad Rafi Mu’arif  
Published: March 2024

Jalan K.H. Hasyim Ashari to Jl. Gatot Subroto is a transportation that plays an important role in daily activities, where Jl. Gatot Subroto is the furniture industry route and the road connects to the Bangil-Rembang toll road. On the K.H. Hasyim Ashari road, the road is connected to the Pantura road so that several points of the road are damaged and bumpy which are caused by heavy vehicles.
On the section Jl. K.H. Hasyim Ashari to Jl. Gatot Subroto The method for this study uses a qualitative method in determining road eligibility, in collecting data by field observations, visual analysis and literature study based on Minister of Public Works Regulation Number 11/PRT/M/2010.
So that in the condition of the Jl. K.H. Hasyim Ashari Until Jl. Gatot Subroto, in accordance with Regulation of the Minister of Public Works No.11/PRT/M/2010, is a road segment with a conditional function-worthy category (LS) so that several components need to be handled as can be seen in tables 4.169 to 4.175
Pemanfaatan Enkripsi Data Berbasis Algoritma Blowfish Pada Aplikasi Password Manager RememberMe!
Authors: Suryanto Christian Rayhan , Fajar Mohammad , Hasniati  
Published: March 2024

Password manager RememberMe merupakan salah satu aplikasi yang dapat digunakan oleh penggunanya untuk mengelola dan melindungi kata sandi dari berbagai aplikasi di internet. Sebagai aplikasi yang mengelola data yang sangat penting, tentunya diperlukan tambahan lapisan keamanan di sisi data pengguna yang tersimpan di basis data. Oleh karena itu penelitian ini bertujuan untuk memanfaatkan algoritma blowfish dalam melakukan enkripsi data pengguna yang akan disimpan di basis data dan meng-evaluasi kinerja aplikasi. Pengumpulan data dilakukan dengan mengevaluasi proses enkripsi dan dekripsi serta observasi kinerja aplikasi password manager RememberMe! terhadap aspek waktu tanggap, ukuran data hasil enkripsi, dan pemakaian bandwitdth. Hasil evaluasi menunjukkan data pengguna khususnya password berhasil dienkrip kemudian disimpan ke basis data serta berhasil didekrip ketika digunakan kembali oleh pengguna. Selain itu pengujian waktu tanggap rata-rata berada dibawah 1 detik, ukuran data enkripsi relatif sebesar 22 byte dan total data bandwidth sent yaitu relatif kurang dari 5 MB.
Analisis Kerusakan Jalan Perkerasan Lentur Menggunakan Metode Pavement Condition Index Pada Ruas Jalan Raya Nasional Bojonegoro – Babad Sta 18+000 S/D 19+200
Authors: Sholahudin Mohamad , Suji’at  
Published: March 2024

Jalan merupakan prasarana transportasi darat yang memiliki peranan sangat penting dalam sektor perhubungan darat, yang mendukung kesinambungan distribusi barang dan jasa untuk mendorong pertumbuhan ekonomi suatu daerah. Begitu juga dengan Jalan Nasional Bojonegoro – Babad yang semakin lama kendaraan yang melintas semakin banyak sehingga tentunya hal ini berpengaruh terhadap kualitas jalan yang dilewati khususnya pada STA 18+000 s/d 19+200 yang terlihat terjadi adanya kerusakan perkerasan. Maka dengan melakukan survei lapangan diperoleh data kerusakan perkerasan yang kemudian dilakukan analisa menggunakan metode pavement condition index sehingga diperoleh hasil bahwa Nilai PCI ruas STA 18+000 s/d 19+200 adalah 64,3% dan berada pada level Good namun yang perlu diperhatikan adalah pada beberapa stasioner terdapat level Fair dengan nilai terendah terjadi pada STA 18+000 sd 18+200, STA 18+700 sd 18+800 dan STA 19+000 sd 19+100
Epidemiology, clinic and prevention of monkeypox. Bibliographic review
Authors: Estrada Zamora Esmeralda Maricela , Salinas Velastegui Verónica Gabriela , Trujillo Chávez María Belén , Coronel Miranda Byron Josue , Chango Moposita Liner Oswaldo 
Published: March 2024

Introduction: Monkeypox, or monkeypox, is a zoonosis endemic in the rural jungle areas of central and western Africa, in humans the first occurrence was in 1970 in the Democratic Republic of Congo. It is caused by a virus belonging to the genus Orthopoxvirus of the Poxviridae family. Objective: to determine the causes and predisposing factors to the outbreak of monkeypox, transmission routes, clinical manifestations, evolution, complications, diagnosis, therapeutic management, prevention and control of infection.Material and methods: a systematic review was carried out in the Medscape, Pubmed, Science Direct and Scielo databases. Thirty-one papers were used.Results: Monkeypox was discovered in 1958 in the city of Copenhagen, capital of Denmark, in monkeys used for research. In 1970, the first case of monkeypox in humans was reported in a child in the Democratic Republic of Congo. Once the diagnostic suspicion is determined, sampling is indicated to confirm infection by nucleic acid amplification test (NAAT) or real-time PCR. PCR is the definitive diagnostic test, can be alone or followed by restriction fragment length polymorphism (RFLP) analysis or sequencing, has high sensitivity and specificity; and a rapid turnaround time of about one day or less. Monkeypox is usually mild and most people recover without treatment.Conclusions: so far in Ecuador 421 cases of monkeypox have been reported, so it is important that public health officials and health care personnel receive training on the risk of the disease, recognition, treatment and isolation of cases. It is important that the country has sufficient PCR tests in public facilities for the confirmation of cases and as a method of prevention, citizens should maintain the biosecurity measures announced by the MSP
Validation of a training model of professional competence management of patient safety in intensive care in the Bachelor of Nursing degree
Authors: Durán Rodríguez Reudis , Hernández Heredia Raúl , Cazull Imbert Irayma , Obret Orphee Rosilé 
Published: March 2024

Introduction: the pedagogical model as a scientific result of educational research, understood as a representation of essential elements of the training process or some of its parts. Objective: to validate a model for the formation of the professional competence "Management of patient safety in intensive care" in the Bachelor's degree in Nursing. Method: a study was carried out at the Baracoa Medical Sciences Branch, belonging to the Guantánamo University of Medical Sciences from 2016-2018, methods such as methodological triangulation were used through the criteria of 20 experts by the Green method. Results: the consensus general of the experts was "strongly in agreement" for the foundations that support the training model of professional competence "Management of patient safety in intensive care" in the Nursing Bachelor's degree and its quality. Conclusions: the training model of professional competence "Management of patient safety in intensive care" is accepted as valid and feasible for its implementation in practice, it constitutes a novel and relevant contribution for the transformation of the training process in the career of Nursing, from the Emergency Nursing subject in the fourth year, which promotes the relationship between the systematization of skills and the development of innovation capacity in students to guarantee patient safety
Implemnetasi Program UKS di SDN Saptorenggo 4 Kecamatan Pakis Kabupaten Malang
Authors: Nuryani Silvi , Wandi  , Moh Zainol Rachman  
Published: March 2024

Latar belakang: Pendidikan merupakan proses yang dilakukan dengan sadar dan terencana. Untuk mencapai kondisi yang optimal dalam melaksanakan proses pembelajaran memerlukan lingkungan yang sehat guna meningkatkan prestasi. Oleh karena itu diperlukan upaya nyata untuk melaksanakan pembangunan pendidikan berbasis lingkungan sehat yang nantinya dapat berpengaruh pada pembangunan karakter siswa yang berkualitas. Salah satunya melalui pengembangan program UKS.
Tujuan: Tujuan dari penelitaian ini adalah untuk mendeskripsikan implementasi program UKS di SDN Saptorenggo 4 Kecamtan Pakis Kabupaten Malang.
Metode: Metode yang digunakan adalah kualitatif dengan pendekatan studi kasus yang bersifat deskriptif. Informan diambil dengan cara purposive sampling dan pengumpulan data berupa wawancara, dokumentasi dan observasi. Sedangkan analisis data menggunakan metode interaktif Miles dan Huberman.
Hasil: Hasil penelitian didapatkan bahwa implementasi program UKS di SDN Saptorenggo 4 masih belum optimal di sebagian aspek yang merujuk pada pedoman pelaksanaan dan pembinaan UKS yang mencakup Trias UKS yaitu pendidikan kesehatan, pelayanan kesehatan, dan pembinaan lingkungan sekolah. Adapun hambatan yang ditemui adalah kurangnya media kesehatan sehingga berdampak pada tingkat literasi siswa, pelaksanaan CTPS belum optimal dikarenakan siswa tidak menggunakan sabun saat mencuci tangan, tidak dilaksanakannya PSN secara berkala.
Kesimpulan: Untuk meningkatkan implementasi program UKS di SDN saptorenggo 4 maka perlu kerjasama antar warga sekolah guna menciptakan lingkungan sekolah yang sehat dan harmonis melalui pengaplikasian kegaiatan Trias UKS.
The Evaluation of Neuroprotective Effect of Nigella sativa Linn Seed Using Zebrafish Model
Authors: Sudha S. , Chitra B. , Nisha S. Arif 
Published: March 2024

Naturally occurring materials that can serve as preservatives in foodstuffs are substances found in their composition. Nigella sativa Linn, a member of the Ranunculaceae family, is a widely recognized medicinal herb with global usage. For centuries, N. sativa L., seeds have been employed to address various ailments and health issues. In behavioral research, the bioactive compound derived from N. sativa L., namely Kaempferol 3-(2-galloyl-alpha-L-arabinopyranoside), has gained significant attention. The escalating prevalence of Alzheimer's disease among elderly individuals worldwide necessitates exploration beyond traditional mammalian and rodent models. This has led to the adoption of zebrafish (Danio rerio) as a unique model organism in biomedical research, behavior analysis and human disorders. Experiments involving scopolamine-induced T-maze, escape, place preference and bite tests have strongly suggested that behavior in zebrafish is governed by conserved regulatory processes. The results of the behavior tests demonstrated that N. sativa L., enhances learning and memory, which was otherwise affected by scopolamine treatment. Notably, a thorough analysis of histoarchitecture revealed no adverse effects of Kaempferol 3-(2-galloyl-alpha-L-arabinopyranoside), which might be a promising therapeutic option for such a multi-factorial Alzheimer's disease.
The Systematic Review of Platelet Rich Plasma Induced Olfactory In Patients With Covid 19
Authors: Satyarini Nidyasari Citraningrum , Rasyidah Salma 
Published: March 2024

Background:Olfactory Dysfunction (OD) is a common problem, with a substantial percentage of instances linked to COVID-19. This comprehensive study sought to assess the efficacy of platelet-rich plasma (PRP) in the treatment of COVID-19-related OD, which included anosmia, hyposmia, and parosmia. Aim : This study examined the efficacy of platelet-rich plasma (PRP), an autologous blood product with elevated growth factors, in treating COVID-19-related olfactory dynsfunction. Methods: By comparing itself to the standards set by the Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) 2020, this study was able to show that it met all of the requirements. So, the experts were able to make sure that the study was as up-to-date as it was possible to be. For this search approach, publications that came out between 2014 and 2024 were taken into account. Several different online reference sources, like Pubmed and SCIENCE DIRECT, were used to do this. It was decided not to take into account review pieces, works that had already been published, or works that were only half done. Result:In the PubMed database, the results of our search brought up 9 articles, whereas the results of our search on SCIENCE DIRECT brought up 108 articles. The results of the search conducted for the last year of 2014 yielded a total 17 articles for PubMed and 16 articles for SCIENCE DIRECT. In the end, we compiled a total of 5 papers, 4 of which came from PubMed and 2 of which came from SCIENCE DIRECT. We included five research that met the criteria. Conclusion: In summary, injecting PRP directly into the olfactory cleft of individuals with post-COVID COD is a successful and simple treatment. We believe that the therapeutic efficacy of PRP injection may vary depending on the time of OD or with repeated doses. Further randomized controlled studies are needed to confirm these findings and explore the long-term impact of this innovative technique.
PECULIARITIES OF THE FUNCTIONING OF LEGAL VOCABULARY IN FICTION PROSE (BASED ON V. HUGO'S "THE LAST DAY OF A MAN SENTENCED TO DEATH" AND G. MUSSEAU'S "I CAN'T LIVE WITHOUT YOU")
Authors: Деденко Виктория Владимировна , Хажокова Эмма Аслановна 
Published: March 2024

В статье предпринята попытка лингвистического анализа произведений В. Гюго «Последний день приговоренного к смерти» и Г. Мюссо «Я не могу без тебя». Особое внимание уделяется функционально-стилистическому аспекту. Установлено, что преобладающее количество юридической лексики, использующихся в текстах проанализированных произведений содержит определенную стилистическую информацию.
The article attempts a linguistic analysis of the works of V. Hugo "The Last Day of a Man Sentenced to Death" and G. Musso "I Cannot Live Without You". Particular attention is paid to the functional and stylistic aspect. It has been established that the predominant amount of legal vocabulary used in the texts of the analyzed works contains certain stylistic information.
ROLE OF COLONIES SETTLEMENTS IN MODERN STRATEGIES OF CRIMINAL PUNISHMENT KYRGYZ REPUBLIC
Authors: Мамаев Омар Жиянбаевич , Мамаева Аманай Жиянбаевна 
Published: March 2024

Создание колоний поселений для осужденных, также известных как колонии трудового поселения или колонии-поселения, является одним из методов уголовного наказания. Эта концепция предполагает, что осужденные будут отправлены на отдаленные территории, где им предоставят возможность трудиться и вносить вклад в общество в условиях относительной изоляции. Такие поселения могут быть предназначены для различных категорий, осужденных, от нарушителей мелких правонарушений до более серьезных преступников.
The creation of settlement colonies for convicts, also known as labor settlement colonies or settlement colonies is one of the methods of criminal punishment. This concept involves convicts being sent to remote areas where they will be given the opportunity to work and contribute to society in relative isolation. Such settlements can be designed for a variety of convicted offenders, from minor offenders to more serious criminals.
ARTIFICIAL INTELLIGENCE IN MEDICINE: CONCEPT AND ROLE IN THE HEALTHCARE SYSTEM
Authors: Щербакова Ирина Викторовна , Эльбердов Азамат Аскерович 
Published: March 2024

В работе представлены результаты анализа содержания понятия «искусственный интеллект» и его значения в сфере медицины. Затрагивается вопрос о перспективах применения технологий искусственного интеллекта в медицине и здравоохранении.
The paper presents an overview of the prospects for the use of artificial intelligence technologies in medicine and healthcare. The history of the development of artificial intelligence is considered.
RUSSIAN-CHINESE COOPERATION: FROM HISTORY TO PROSPECTS
Authors: Кристюков Артем Алексеевич , Лобанова Валерия Владимировна , Лещиловский Давид Cтаниславович 
Published: March 2024

В первой четверти ХХI века сотрудничество между Россией и КНР получило дополнительный импульс в виду сложившейся конфронтации между этими странами с одной стороны и Северо атлантическим альянсом с другой. Авторы дают анализ российско - китайских отношений в контексте современных экономических и политических условий, а так же делают ряд предложений по вопросам расширения сотрудничества.
In the first quarter of the XXI century, cooperation between Russia and China received an additional impetus in view of the current confrontation between these countries on the one hand and the North Atlantic Alliance on the other. The authors analyze Russian-Chinese relations in the context of modern economic and political conditions and make a number of proposals on expanding cooperation.
STUDY OF THE COMPOSITION OF COTTONSEED OIL SOAPSTOCK AND DEDISTILLATE AS SOURCES OF FATTY ACIDS
Authors: Хусанова Нафиса Сайдуллаевна , Гиясов Жавлон Шавкатович , Исроилова Шоира Жамшидовна , Серкаев Камар Пардаевич 
Published: March 2024

В связи с содержанием в составе госсипола и его производных, фосфолипидов и других побочных веществ, отходы комплексной рафинации хлопкового масла - соапcток и деодистиллят не представляют из себя готового сырья для мыловарения. В работе представлены результаты исследования состава соапстока и деодистиллята из хлопкового масла и приведены предпосылки по улучшению качества получаемых продуктов.
Due to the content of gossypol and its derivatives, phospholipids and other by-products in the composition, the waste from the complex refining of cottonseed oil - soastock and deodistillate do not represent ready-made raw materials for soap making. The paper presents the results of a study of the composition of soapstock and deodistillates from cottonseed oil and provides prerequisites for improving the quality of the products obtained.
ROLE POSITIONS OF A UNIVERSITY TEACHER IN THE CONTEXT OF THE MODERN EDUCATION PARADIGM
Authors: Кругликов Виктор Николаевич 
Published: March 2024

В статье на основе проведённого исследования рассматриваются базовые ролевые позиции преподавателя вуза, их роль и значение с точки зрения эффективности подготовки специалиста в контексте современной образовательной парадигмы, требующей перехода преподавателей на субъект-субъектную модель построения и ведения образовательного процесса.
The article, based on the conducted research, examines the basic role positions of a university teacher, their role and significance from the point of view of the effectiveness of specialist training in the context of the modern educational paradigm, which requires the transition of teachers to a subject-subject model of constructing and conducting the educational process.
БРУЦЕЛЛЕЗ И ЕГО РАСПРОСТРАНЕНИЕ В РЕСПУБЛИКЕ ДАГЕСТАН
Authors: Улуханова Лала Уджаговна , Пашаева Саида Алимпашаевна 
Published: March 2024

По уровню наносимого экономического ущерба бруцеллез продолжает занимать среди зоонозных инфекций одно из ведущих мест, а его ликвидация остается актуальной глобальной проблемой. Обстановка по бруцеллезу в республике Дагестан за последние 5 лет является нестабильной и определяется выявлением бруцеллеза среди сельскохозяйственных животных и индивидуальных хозяйствах.
In terms of the level of economic damage caused, brucellosis continues to occupy one of the leading places among zoonotic infections, and its elimination remains an urgent global problem. The brucellosis situation in the Republic of Dagestan over the past 5 years has been unstable and is determined by the identification of brucellosis among farm animals and individual farms.
EFFECT OF MAGNETIC FLUX CREEP ON CRITICAL CURRENT IN PERCOLATIVE SUPERCONDUCTORS
Authors: Кузьмин Юрий Игоревич 
Published: March 2024

Рассматривается влияние крипа магнитного потока на критические токи в перколяционных высокотемпературных сверхпроводниках. Сделаны оценки значений критического тока и электрического поля, индуцированного крипом вихрей.
The effect of magnetic flux creep on critical currents in percolation high-temperature superconductors is considered. The values of the critical current and electric field induced by vortex creep are estimated.
ASSOCIATION OF POLYMORPHISM OF THE BETA-CASEIN GENE WITH ECONOMIC EFFICIENCY OF USING OF WHITE AND BLACK CATTIE
Authors: Валитов Фарит Равилович , Парамонова Мария Алексеевна , Валитова Руфина Фаритовна 
Published: March 2024

В статье идет речь о полиморфизме гена бета-казеина у поголовья крупного рогатого скота, разводимого в условиях Республики Башкортостан. В ходе исследования методом ПЦР-ПДРФ установлено влияние различных генотипов изученного гена на показатели молочной продуктивности и хозяйственно полезные признаки. Выявлены разнонаправленные корреляционные связи между основными показателями молочной продуктивности (удой, жир, белок) и полиморфизмом гена CSN2.
The article is devoted to studying of polymorphism of the beta-casein gene of cattle which is bred in the Republic of Bashkortostan. Using the PCR-RFLP method, the influence of different variants of the studied gene on the indicators of milk productivity is found. The multidirectional correlations between key indicators of milk productivity (yield, fat and protein) and polymorphism of the CSN2 gene are revealed.
ASSESSMENT OF THE CURRENT ECOLOGICAL STATE OF THE LIPETSK REGION IN CONDITIONS OF ANTHROPOGENIC IMPACT
Authors: Щербин Александр Олегович 
Published: March 2024

Антропогенные факторы по своей значимости оказывают весомое влияние на окружающую среду. В статье представлена оценка современного экологического состояния металлургического региона Липецкой области, развивающегося на принципах ответственного отношения к окружающей среде, высокой социальной ответственности и высокого качества управления по системе ESG.
Anthropogenic factors in their importance have a significant impact on the environment. The article presents an assessment of the current ecological state of the metallurgical region of the Lipetsk region, which is developing on the principles of responsible attitude to the environment, high social responsibility and high quality management according to the ESG system.