bluuebunny/crossref_metadata_2025_split huggingface dataset:
Traits of insect herbivores and target weeds associated with greater biological weed control establishment and impact
Authors: Panta Sujan , Schwarzländer Mark , Weyl Philip S. R. , Hinz Hariet L. , Winston Rachel L. , Eigenbrode Sanford D. , Harmon Bradley L. , Bacher Sven , Paynter Quentin 
Published: February 2024

AbstractImproving success rates of classical weed biocontrol programs is an ongoing effort that requires a variety of different approaches. Previous assessments indicated biocontrol agent taxonomy and feeding characteristics and weed life history traits are associated with better control outcomes. We examined weed biocontrol releases for correlations between biocontrol agent and target weed traits associated with different levels of reported establishment and control. Data collated in the 5th edition of ‘Biological Control of Weeds: A World Catalogue of Agents and Their Target Weeds’ were used as the basis for this global analysis. Published literature was used to augment the catalog with data for eight biocontrol agent traits and four target weed traits. Biocontrol agent establishment and impact data were analyzed against these traits using generalized linear mixed models and categorical models, respectively. Analyses for biocontrol agent establishment reveal the following agent traits were correlated with a greater probability of establishment: being an internal feeder, feeding on above-ground plant tissues, multivoltine agents and agents that feed during both their adult and immature life stages. Insect taxon did not affect establishment except for the order Lepidoptera, which had the lowest establishment probability. For weed traits, those occurring in aquatic or riparian habitats were associated with a higher probability of biocontrol agent establishment. Regarding agent impact, using the definition categories in the catalog, agents feeding externally and on vegetative plant tissues, multivoltine agents and those with both adult and immature plant-feeding life stages were strongly correlated with greater impact. Perennials, reproducing only vegetatively and invading aquatic or riparian habitats were associated with greater biocontrol impact. Our findings could facilitate both the prioritization of invasive plants targeted for biocontrol and the selection of suitable biocontrol agent candidates, which should further improve biocontrol project outcomes.
Self-Burdensomeness, Self-Esteem and Suicidal Ideation
Authors: Teismann Tobias , Joiner Thomas E. , Robison Morgan , Brailovskaia Julia 
Published: February 2024

Abstract
Background
Low self-esteem and self-burdensomeness have been proposed as risk factors for suicidal ideation. Yet, self-burdensomeness may be more relevant to suicidal ideation than low self-esteem. The purpose of the present study was to investigate the association between self-esteem, self-burdensomeness, and suicidal ideation in a sample of adult outpatients.

Methods
Data from N = 202 patients (66.3% female; age: M[SD] = 39.87 [13.31], range: 19–73) who started therapy at an outpatient clinic were collected. A subsample of n = 111 patients (68.5% female; age: M[SD] = 38.50 [13.48], range: 20–73) also took part in a second assessment three-months later.

Results
Self-burdensomeness was shown to predict suicidal ideation concurrently and prospectively – after controlling for age, gender, depression, and self-esteem. Furthermore, self-burdensomeness completely mediated the association between self-esteem and suicidal ideation. However, the reverse relationship, where the association between self-burdensomeness and suicidal ideation is mediated by self-esteem, was not supported.

Conclusions
Self-burdensomeness might be understood as a driver of suicidal ideation. Findings point to the possibility that a focus on self-burdensomeness and/or low self-esteem might be relevant in the treatment of suicidal patients.
Learning by Doing or Doing Without Learning? The Potentials and Challenges of Activity-Based Learning
Authors: Skulmowski Alexander 
Published: February 2024

AbstractEngaging learners in activities is an important instructional method. However, the learning-by-doing approach also poses some risks. By analyzing the differences between various types of learning activities, issues of activity-based learning are revealed and discussed. Activity-based learning can consist of relatively simple patterns of motor activity or may involve additional task-related knowledge, resulting in complex activities. Excessive movement or failure to properly integrate motor activity into a task can lead to problems for motor activity–based learning. Elaborate activities, such as letting learners generate drawings, can quickly evolve to secondary tasks in their own right. Demanding learning tasks can create their own cognitive load, resulting in less working memory capacity being available for engaging with the actual content. If activity-based interventions are to be used, as many redundant aspects as possible need to be avoided while providing additional guidance to learners. In addition, it is necessary to consider how task demands transform once tasks are shifted from the physical to the digital world in order to properly acknowledge potential increases in cognitive load. Taken together, this review connects educational and cognitive perspectives on activity-based learning to arrive at models and recommendations that are of high relevance for the digital transformation of education and learning.
The values of cultural goods and cultural capital externalities: state of the art and future research prospects
Authors: Bille Trine 
Published: February 2024

AbstractCultural economics has largely looked toward environmental economics and used non-market valuation techniques such as contingent valuation to estimate the total economic value of cultural goods. These methods are well suited to the valuation of cultural heritage goods, where the benefits are mostly related to the level of supply and mainly take the form of existence and bequest values. This stands in contrast to cultural institutions such as theatres, libraries, exhibitions, and concerts, where the value is produced, when the goods are consumed. For this type of cultural goods, I suggest that cultural economics rather turn to find inspiration in the economics of education. The value of schooling can be divided into private returns and social returns (human capital externalities). Likewise, the value of cultural consumption can have a private and a public component, where I suggest labeling the public component cultural capital externalities. The idea is that when private consumption of arts and culture is taking place, the individual will accumulate cultural capital. This accumulated cultural capital can impact other people (e.g., through changed behavior, future decisions or interactions) and create externalities, i.e., the cultural capital externalities. The size of the externalities is expected to increase (or decrease) with the level of consumption. Without the consumption by the users, no externalities are produced. While this is one of the most fundamental arguments for cultural policy, it has not yet been extensively studied within cultural economics.
An encoding approach for stable change point detection
Authors: Wang Xiaodong , Hsieh Fushing 
Published: February 2024

AbstractWithout imposing prior distributional knowledge underlying multivariate time series of interest, we propose a nonparametric change-point detection approach to estimate the number of change points and their locations along the temporal axis. We develop a structural subsampling procedure such that the observations are encoded into multiple sequences of Bernoulli variables. A maximum likelihood approach in conjunction with a newly developed searching algorithm is implemented to detect change points on each Bernoulli process separately. Then, aggregation statistics are proposed to collectively synthesize change-point results from all individual univariate time series into consistent and stable location estimations. We also study a weighting strategy to measure the degree of relevance for different subsampled groups. Simulation studies are conducted and shown that the proposed change-point methodology for multivariate time series has favorable performance comparing with currently available state-of-the-art nonparametric methods under various settings with different degrees of complexity. Real data analyses are finally performed on categorical, ordinal, and continuous time series taken from fields of genetics, climate, and finance.
Unveiling the future: precision pharmacovigilance in the era of personalized medicine
Authors: Silva Lurdes , Pacheco Teresa , Araújo Emília , Duarte Rita J. , Ribeiro-Vaz Inês , Ferreira-da-Silva Renato 
Published: February 2024

AbstractIn the era of personalized medicine, pharmacovigilance faces new challenges and opportunities, demanding a shift from traditional approaches. This article delves into the evolving landscape of drug safety monitoring in the context of personalized treatments. We aim to provide a succinct reflection on the intersection of tailored therapeutic strategies and vigilant pharmacovigilance practices. We discuss the integration of pharmacogenetics in enhancing drug safety, illustrating how genetic profiling aids in predicting drug responses and adverse reactions. Emphasizing the importance of phase IV—post-marketing surveillance, we explore the limitations of pre-marketing trials and the necessity for a comprehensive approach to drug safety. The article discusses the pivotal role of pharmacogenetics in pre-exposure risk management and the redefinition of pharmacoepidemiological methods for post-exposure surveillance. We highlight the significance of integrating patient-specific genetic profiles in creating personalized medication leaflets and the use of advanced computational methods in data analysis. Additionally, we examine the ethical, privacy, and data security challenges inherent in precision medicine, emphasizing their implications for patient consent and data management.
Horizontal Mergers and Supplier Power
Authors: Perkins Joe , Shekhar Shiva 
Published: February 2024

AbstractSupplier market power—such as the ability of branded goods suppliers to dictate terms to retailers—is an important feature of many markets. We show that supplier power can counteract the effects of downstream mergers on consumer prices where there are two-part contracts. This is because greater market power allows suppliers to set contracts that internalise partially the impact of the merger on downstream prices. Post-merger, the supplier reduces the per-unit price at which it supplies the merged downstream firms, with the aim of maintaining total industry profitability—and then recoups the profits via a larger fixed fee. We modify the standard upward pricing pressure (UPP) formula to account for the supplier’s response to a horizontal merger in the downstream market, while preserving much of the simplicity of the standard approach.
Publicity’s Misinformation Problem
Authors: Koreman Sam 
Published: February 2024

AbstractThis paper argues that everyday practices crucial for ensuring politically engaged citizens such as sharing news articles or deliberating about potential laws can also be responsible for undermining the state’s efforts to publicize the law. Theorists view publicity—a requirement that laws should be public and accessible—as having crucial normative and practical importance in liberal democracy and, more broadly, in ensuring the rule of law. Due to egalitarian concerns, laws are often long, complex, and specific to ensure that street-level bureaucrats exercise low levels of discretion in applying the law. This—what I deem the institutional publicity problem—means that the law is so inaccessible that busy, everyday citizens must turn to third-party sources to understand policymaking. These intermediaries often make mistakes promulgating the law. Misinformation is hard to counteract, and pre-existing beliefs affect information acceptance. This all represents a behavioral publicity problem: morally and legally permissible actions can complicate and undermine reasonable efforts of citizens to learn about the law. I argue that the state is caught between a rock and a hard place. While there are benefits to having the state fight against misinformation, it also raises serious concerns about democratic engagement.
Defending behavior in school bullying: The role of empathic self-efficacy, social preference, and student-teacher relationship
Authors: Levantini Valentina , Gelati Carmen , Camodeca Marina 
Published: February 2024

AbstractBeing able to defend victims of school bullying is central in any intervention; thus, it seems paramount to investigate which factors may contribute to defending behavior. The present report aims to investigate whether empathic self-efficacy is associated with helping behavior and whether interpersonal factors (i.e., social preference and student-teacher relationship) may interact with it. The sample comprised 249 middle-school students (47.80% boys) aged 11–14 years, who received peer nominations on defending behavior and social preference. Self-reports were used to assess empathic self-efficacy and the relationship with the teachers. Results highlight a positive association between empathic self-efficacy and defending behavior when social preference and a positive relationship with teachers were average or high but not when they were low. Results are discussed in light of the importance of considering individual and interpersonal factors to understand defending in bullying situations and to develop intervention programs.
Potential of Soil Conditioners to Mitigate Deficit Irrigation Impacts on Agricultural Crops: A Review
Authors: Abdelfattah Ahmed , Mostafa Harby 
Published: February 2024

AbstractIn light of the current water scarcity, one strategy for reducing water consumption in irrigated agriculture is to reduce the amount of irrigation water compared to full crop irrigation or in other words deficit irrigation. Deficit irrigation management may be a critical issue due to climate change. Incorporation of different soil conditioners can improve soil hydro-physical properties and mitigate negative effects in water-stressed conditions. Recent review articles either addressed specific crop behavior under water deficit or covered a single type of soil conditioners. This manuscript represents an inclusive review providing insight into deficit irrigation methods incorporated with different soil conditioners. Crop response to deficit irrigation is discussed in the light of some mathematical models. Three main types of soil conditioners are covered: bentonite, biochar, and super-absorbent polymers. Mechanisms associated with effects of each conditioner to enhance soil water retention is highlighted as well. Previous study findings were discussed comparatively and future prospective, recommendations and challenges were addressed.
Genetic and functional modulation by agonist MRS5698 and allosteric enhancer LUF6000 at the native A3 adenosine receptor in HL-60 cells
Authors: Gao Zhan-Guo , Chen Weiping , Gao Ray R. , Li Jonathan , Tosh Dilip K. , Hanover John A. , Jacobson Kenneth A. 
Published: February 2024

AbstractThe A3 adenosine receptor (AR) is an important inflammatory and immunological target. However, the underlying mechanisms are not fully understood. Here, we report the gene regulation in HL-60 cells treated acutely with highly selective A3AR agonist MRS5698, positive allosteric modulator (PAM) LUF6000, or both. Both pro- and anti-inflammatory genes, such as IL-1a, IL-1β, and NFκBIZ, are significantly upregulated. During our observations, LUF6000 alone produced a lesser effect, while the MRS5698 + LUF6000 group demonstrated generally greater effects than MRS5698 alone, consistent with allosteric enhancement. The number of genes up- and down-regulated are similar. Pathway analysis highlighted the critical involvement of signaling molecules, including IL-6 and IL-17. Important upstream regulators include IL-1a, IL-1β, TNF-α, NF-κB, etc. PPAR, which modulates eicosanoid metabolism, was highly downregulated by the A3AR agonist. Considering previous pharmacological results and mathematical modeling, LUF6000’s small enhancement of genetic upregulation suggested that MRS5698 is a nearly full agonist, which we demonstrated in both cAMP and calcium assays. The smaller effect of LUF6000 on MRS5698 in comparison to its effect on Cl-IB-MECA was shown in both HL-60 cells endogenously expressing the human (h) A3AR and in recombinant hA3AR-expressing CHO cells, consistent with its HL-60 cell genetic regulation patterns. In summary, by using both selective agonists and PAM, we identified genes that are closely relevant to immunity and inflammation to be regulated by A3AR in differentiated HL-60 cells, a cell model of neutrophil function. In addition, we demonstrated the previously uncharacterized allosteric signaling-enhancing effect of LUF6000 in cells endogenously expressing the hA3AR.
Participatory hackathon to determine ecological relevant endpoints for a neurotoxin to aquatic and benthic invertebrates
Authors: Rasmussen Sofie B. , Bosker Thijs , Ramanand Giovani G. , Vijver Martina G. 
Published: February 2024

AbstractThe aim of this study is twofold: i) to determine innovative yet sensitive endpoints for sulfoxaflor and ii) to develop best practices for innovative teaching in ecotoxicology. To this end, a group of 52 MSc students participated in an environmental hackathon, during which they did creative toxicity testing on 5 freshwater invertebrate species: Daphnia magna, Chironomus riparius, Asellus aquaticus, Lymnaea stagnalis, and Anisus vortex. Involving the students in an active learning environment stimulated increased creativity and productivity. In total, 28 endpoints were investigated, including standard endpoints (e.g., mortality) as well as biomechanistic and energy-related endpoints. Despite high variances in the results, likely linked to the limited lab experience of the students and interpersonal differences, a promising set of endpoints was selected for further investigation. A more targeted follow-up experiment focused on the most promising organism and set of endpoints: biomechanistic endpoints of C. riparius larvae. Larvae were exposed to a range of sulfoxaflor concentrations (0.90–67.2 μg/L) for 21 days. Video tracking showed that undulation and swimming were significantly reduced at 11.1 μg sulfoxaflor/L after 9 days of exposure, and an EC50 = 10.6 μg/L for mean velocities of the larvae in the water phase was found. Biomechanistic endpoints proved much more sensitive than mortality, for which an LC50 value of 116 μg/L was found on Day 9. Our results show that performing a hackathon with students has excellent potential to find sensitive endpoints that can subsequently be verified using more targeted and professional follow-up experiments. Furthermore, utilising hackathon events in teaching can increase students’ enthusiasm about ecotoxicology, driving better learning experiences.
Opportunity entrepreneurship after 65: Relevant factors in OECD countries
Authors: Amorós José Ernesto , Leporati Marcelo , Torres-Marín Alfonso Jesús , Roses Sergio 
Published: February 2024

AbstractThis research aims to analyze individual and national level factors that influence opportunity-driven senior entrepreneurship (people older than 65 years) in a group of 12 OECD countries. At this age most people in developed economies could choose between retiring, continuing working, or starting a new venture. It is important to understand the motivations behind their decision. We use data from the Global Entrepreneurship Monitor (GEM), to identify the effect of attitudes, perceptions, and aspirations as well as their sociodemographic characteristics. The sample consists of 24,139 observations from individuals older than 65 years. Additionally, we used the Human Development Index (HDI) – from the United Nations database–, to measure the country's level of development. Because of the nested nature of the data, we estimate our models using a multilevel logistic regression. Our results show that income, education, and occupation, in conjunction with the level of human development of a country have a significant influence on the probability of entrepreneurship by opportunity for senior individuals (+ 65). This research has policy and practical implications related to the decision of senior people to explore the creation of a new venture instead of opting for other alternatives such as retiring.
Optical Susceptibility of Hybrid Semiconductor Quantum Dot-Metallic Nano Ellipsoid System Under the Effect of the Exciton-Plasmon Coupling Field Interaction
Authors: Abd-Elsamie Asmaa M. , Abd-Elnabi Somia 
Published: February 2024

Abstract
We examine the optical susceptibility of the semiconductor quantum dot-metallic nano ellipsoid system under the effect of the exciton-plasmon coupling field. Also, we determine the optical susceptibility for the semiconductor quantum dot and the three metallic nano ellipsoids under the responses to the total effect of the three applied electromagnetic fields. The phenomena of Fano-resonance with amplification and Autler-Town doublet peaks are obtained and discussed. The phenomena of Fano-resonances and Autler-Town doublet peaks can be controlled by varying the depolarization factor of nano ellipsoid, semi-axes, and other parameters in a hybrid system.
Black-white hole pattern: an investigation on the automated chronic neuropathic pain detection using EEG signals
Authors: Tasci Irem , Baygin Mehmet , Barua Prabal Datta , Hafeez-Baig Abdul , Dogan Sengul , Tuncer Turker , Tan Ru-San , Acharya U. Rajendra 
Published: February 2024

AbstractElectroencephalography (EEG) signals provide information about the brain activities, this study bridges neuroscience and machine learning by introducing an astronomy-inspired feature extraction model. In this work, we developed a novel feature extraction function, black-white hole pattern (BWHPat) which dynamically selects the most suitable pattern from 14 options. We developed BWHPat in a four-phase feature engineering model, involving multileveled feature extraction, feature selection, classification, and cortex map generation. Textural and statistical features are extracted in the first phase, while tunable q-factor wavelet transform (TQWT) aids in multileveled feature extraction. The second phase employs iterative neighborhood component analysis (INCA) for feature selection, and the k-nearest neighbors (kNN) classifier is applied for classification, yielding channel-specific results. A new cortex map generation model highlights the most active channels using median and intersection functions. Our BWHPat-driven model consistently achieved over 99% classification accuracy across three scenarios using the publicly available EEG pain dataset. Furthermore, a semantic cortex map precisely identifies pain-affected brain regions. This study signifies the contribution to EEG signal classification and neuroscience. The BWHPat pattern establishes a unique link between astronomy and feature extraction, enhancing the understanding of brain activities.
Nash equilibria for relative investors with (non)linear price impact
Authors: Bäuerle Nicole , Göll Tamara 
Published: February 2024

AbstractWe consider the strategic interaction of n investors who are able to influence a stock price process and at the same time measure their utilities relative to the other investors. Our main aim is to find Nash equilibrium investment strategies in this setting in a financial market driven by a Brownian motion and investigate the influence the price impact has on the equilibrium. We consider both CRRA and CARA utility functions. Our findings show that the problem is well-posed as long as the price impact is at most linear. Moreover, numerical results reveal that the investors behave very aggressively when the price impact is close to a critical parameter.