bluuebunny/crossref_metadata_2025_split huggingface dataset:
The complex social, cultural and psychological drivers of the ‘chemsex’ experiences of men who have sex with men: a systematic review and conceptual thematic synthesis of qualitative studies
Authors: Mundy Edward , Carter Alexander , Nadarzynski Tom , Whiteley Christopher , de Visser Richard O. , Llewellyn Carrie D. 
Published: February 2025

IntroductionChemsex’ is the sexualised use of drugs among men who have sex with men (MSM). Past systematic reviews have primarily focussed on quantitative research exploring the key characteristics and health consequences of chemsex. However, a large body of qualitative literature exists, drawing on different theoretical frameworks.MethodsA systematic review and thematic synthesis of the qualitative research on chemsex was conducted with the aim of exploring the chemsex experiences of MSM in the context of substance misuse and addictions, and to reviewing their underlying theoretical frameworks. Six databases were searched, and 43 papers were included in the review.ResultsThe thematic synthesis resulted in four key themes: ‘characterising chemsex’, ‘the context around chemsex’, ‘the chemsex experience’, and ‘harms, saying safe, and stopping chemsex’. Only nine papers explicitly drew on theoretical frameworks, which were broadly divided into two categories: those which drew on psychological theories, and those that framed chemsex as a social and cultural phenomenon.DiscussionThe results of the thematic synthesis add further understanding of the key characteristics of chemsex as well as some of the complex social and psychological drivers which may shape why people have chemsex. Finally, the review highlights the clinical implications and inherent complexities in providing clinical services for those reporting chemsex and the need for greater application of theory to advance our understanding of chemsex and continue to develop appropriate forms of therapeutic support.Systematic review registrationhttps://osf.io/j6k9r/.
A pilot mixed methods randomized control trial investigating the feasibility and acceptability of a culturally tailored intervention focused on beliefs, mistrust and race-congruent peer support for Black adults with diabetes
Authors: Wen Meng-Jung , Maurer Martha , Pickard Annika L. , Hansen Makenzie , Shiyanbola Olayinka O. 
Published: February 2025

IntroductionBlack adults disproportionately experience poor glycemic control and medication nonadherence, yet few diabetes self-management programs address their unique health beliefs, provider mistrust and sociocultural barriers to taking diabetes medications. This 6-month pilot randomized feasibility trial compared a culturally tailored diabetes self-management program, incorporating beliefs about diabetes, mistrust, and race-congruent peer support to a standard diabetes program.MethodsAn embedded mixed methods design examined the feasibility of the pilot trial, including recruitment, retention, intervention adherence and participant acceptability. Data were collected through participant self-reported questionnaires, field notes, semi-structured interviews, and focus groups. Qualitative content analysis inductively explored participants’ feedback on the program, participation barriers and potential strategies to overcome the challenges. Mixed methods integration was implemented using a side-by-side joint display to compare, synthesize and interconnect the quantitative and qualitative results across all feasibility domains.ResultsThirteen participants (93%) completed the trial, demonstrating high adherence and retention. Community outreach and a prerequisite orientation using motivational interviewing were feasible and appropriate to recruit potential participants. Participants expressed high satisfaction and acceptability, highlighting the importance of peer support, cultural relevant content and a safe space for sharing experiences. Barriers to participation were identified including schedule conflicts and difficulties in engagement.DiscussionFuture large-scale effectiveness trials should consider combining multimedia into recruitment methods, tailoring the program to address medication-taking goals, and addressing social and environmental barriers to support sustained lifestyle changes.
Utilizing physical educators to monitor muscular strength and neuromuscular control among children with varied recess time
Authors: Webb G. Kate , Zhang Yan , Rhea Deborah J. 
Published: February 2025

IntroductionInactivity levels among children are climbing at alarming rates, leading to a lack of physical activities that produce muscular strength (MusS) development, which in turn creates effective neuromuscular control (NC) development. Developing appropriate MusS during childhood decreases the chances of physical injuries and many chronic diseases such as type II diabetes and cancer, which leads to healthier, active future adults. The purpose of this study was to utilize the physical education setting to examine MusS and NC factors in the Fall and Spring (Time 1 to Time 2) of one school year in a predominately Hispanic sample of second-grade children who received 60 min or 20 min of daily recess.MethodsThis quasi-experimental pre-test/post-test study administered four MusS tests and one NC test to District 1 (N = 59) which received 60 min of recess daily (intervention), and District 2 (N = 49) which received one 20 min daily recess (control). ANCOVAs were run for group differences at Time 2 while controlling for Time 1.ResultsIntervention children significantly outperformed control children on the single leg 3-hop muscular strength test F(1,105) = 13.1, p &lt; .001, n2 = .05, and the neuromuscular control side-step test F(1,105) = 4.77, p = .03, n2 = .04. Between group ANCOVAs controlling for body fat percentages showed the single leg 3-hop test remained significant between groups F(1,91) = 23.5, p &lt; .001, n2 = .09.DiscussionIncreased recess was shown to aid in improved lower body muscular strength and neuromuscular control among second grade children, even when controlling for body fat percentages. As 70% of American children are not participating in the recommended daily activity guidelines, and roughly 20% of American children are overweight, exploring movement opportunities for children and efficient means of monitoring MusS and NC is pivotal to future health and movement functions of children.
Representing unsegmented vessels using available vascular data for bioheat transfer simulation
Authors: Amare Rohan , Bahadori Amir A. , Eckels Steven 
Published: February 2025

IntroductionA primary challenge with voxel domains generated from imaging data is associated with voxel resolution. Due to the dimensional scale of blood vessels, not all vessels are captured in a given voxel resolution, leading to discontinuous blood vessels in the segmentation. Pre-capillary vessels like arterioles, which provide the highest resistance to blood flow, are often modeled with tissue as a porous domain due to resolution limitations. This results in a loss of information that could have been modeled if these vessels were segmented and modeled distinctly from the capillary bed.MethodsThis paper focuses on developing mathematical equations to calculate the flow resistance of unsegmented vasculature with reference to flow resistance of available segmented vascular data. A 3D vascular domain of 32 terminal vessels and five generations of bifurcation is simulated. Each generation is successively removed and substituted with the new flow resistance equations to analyze the error in heat transfer due to a lack of segmentation data.ResultsThe effect of using mathematical equations of flow resistance on bioheat transfer is analyzed. Two methods are proposed and demonstrated to show considerable error reduction in bioheat transfer.DiscussionVery high image resolution, which could allow modeling of pre-capillary vessels, increases the computational cost of the entire simulation domain. Instead, a mathematical representation of the pressure drop induced in these unsegmented blood vessels is used. The proposed methods show potential in reducing the error resulting from the lack of segmentation data, improving the accuracy of bioheat transfer simulations.
YOLOv8-CBAM: a study of sheep head identification in Ujumqin sheep
Authors: Qin Qing , Zhou Xingyu , Gao Jiale , Wang Zhixin , Naer A. , Hai Long , Alatan Suhe , Zhang Haijun , Liu Zhihong 
Published: February 2025

IntroductionThe facial coloration of sheep is not only a critical characteristic for breed and individual identification but also serves as a significant indicator for assessing genetic diversity and guiding selective breeding efforts.MethodsIn this study, 201 Ujumqin sheep were used as research objects and 1713 head image data were collected. We delineated feature points related to the facial coloration of Ujumqin sheep and successfully developed a head color recognition model (YOLOv8-CBAM) utilizing the YOLOv8 architecture in conjunction with the CBAM attention mechanism.ResultsThe model demonstrated impressive performance in recognizing four head color categories, achieving an average precision (mAP) of 97.7% and an F1 score of 0.94. In comparison to YOLOv8n, YOLOv8l, YOLOv8m, YOLOv8s, and YOLOv8x, the YOLOv8-CBAM model enhances average accuracy by 0.5%, 1%, 0.7%, 0.7%, and 1.6%, respectively. Furthermore, when compared to YOLOv3, the improvement is 1%, while YOLOv5n and YOLOv10n show increases of 1.4% and 2.4%, respectively.DiscussionThe findings indicate that the smaller model exhibited superior performance in the facial color recognition task for Ujumqin sheep. Overall, the YOLOv8-CBAM model achieved high accuracy in the head color recognition task, providing reliable technical support for automated sheep management systems.
Residue depletion profile and withdrawal interval estimation of ivermectin in eggs following topical administration of injectable ivermectin to domestic chickens (Gallus domesticus): a pilot study
Authors: Mercer Melissa A. , Davis Jennifer L. , Wetzlich Scott E. , Clapham Maaike O. , Tell Lisa A. 
Published: February 2025

IntroductionTopical ivermectin is commonly prescribed extra-label for the control of mite infestations in backyard chicken flocks in the US.MethodsDomestic laying hens (n = 8; 78 weeks of age, weight 1.7–2.2 kg) were administered injectable ivermectin solution topically over the jugular vein (0.4 mg/kg every 7 days for 2 doses). Ivermectin concentrations in egg white and egg yolk were determined using UPLC with fluorescence detection.ResultsThe average period between eggs laid was 1.52 days. Ivermectin preferentially distributed to the egg yolk with an observed Cmax of 3.54 ng/g occurring at observed Tmax of 6.6 days and a T1/2 of 9.5 days. Residues persisted at low concentrations in egg yolk for up to 71 days after the final dose. WDIs for the egg yolk matrix were estimated using the FDA, EMA, and terminal-elimination half-life multiplier methods (HLM). The longest estimated WDI was 102 days for the EMA 95/95 method (95% confidence interval for 95th population percentile) with the limit of detection (LOD; 0.03 ng/g) set as the maximum residue limit. The FDA 95/99 method using the LOD as the tolerance estimated an 81 day WDI, the HLM method estimated a 96 day WDI.DiscussionThis study improves the understanding of the residue depletion kinetics of ivermectin in eggs after topical administration to older hens with inconsistent egg production. Ivermectin is systemically absorbed following topical administration of the injectable formulation in domestic egg laying chickens, resulting in prolonged egg residues. Ivermectin is preferentially distributed to the egg yolk over the egg white following topical administration of the injectable formulation in egg laying chickens. Since plasma kinetics were not evaluated, the impact of systemic exposure on egg residue kinetics following topical administration remains unknown. The results provide insight into how the estimated ivermectin egg WDIs using regulatory methods differ based on the maximum residue limit/tolerance applied and portion of the terminal elimination phase sampled.
KH. NOER ALIE IS A MULTI-DIMENSIONAL CLERICAL FIGURE AND HIS WORK IN SOCIETY
Authors: Ahmas Kholilullah 
Published: February 2025

Research on the figure of KH. Noer Alie as a multi-dimensional scholar, is felt to be so important for academics, da'ie, educators and the wider community. This is because K.H. Noer Ali is a scholar, preacher, and fighter who was directly involved in confrontations with Dutch and Japanese colonizers during the revolutionary period and then took part in the community in the fields of da'wah, education and society in the post-revolutionary era. From the continuous struggle that is considered to be a major contribution to the existence of the Unitary State of the Republic of Indonesia (NKRI), finally the Indonesian Government has conferred the title of national hero to K.H. Noer Ali for his services for Indonesian independence. The objectives of the study are; first; to analyze the concepts of thought, approaches and methods of K.H. Noer Ali in various gait which include politics, education, da'wah and social in society, second; to find out the implementation of the concepts, approaches and methods of K.H. Noer Ali's gait in society . This research uses a qualitative approach with library research sources, library research is research that reveals facts or data in research obtained through books, journals and other scientific works related to the object of research. This research uses several types of methods, including; description, historical and sociological methods. From some literature, it was found that KH Noer Alie is a cleric who is dubbed as a multi-dimensional cleric figure, this is based on his extensive role and work in the community covering various aspects of life. In addition to being a cleric figure, KH. Noer Alie is also known as a warrior figure, da'ie figure, educator figure, political figure, organizational figure and community figure. The results of this study indicate that the concept of K.H. Noer Alie's work comes from the Qur'an and Hadith as the main source of Ahlu Sunnah waljama'ah Islam, this concept emphasizes strengthening a good understanding of Islamic teachings based on these two sources. In taking part, the approach taken by K.H Noer Alie is through political, educational, da'wah and social struggles, the methods used are exemplary methods, deep attention and direct interaction with the community.
Prevalência e fatores associados a insuficiências cardíaca em idosos com e sem Diabetes Mellitus tipo 2
Authors: Neiva Silvana Pinheiro , Teixeira Mônica Maria , Barreto Bárbara Teixeira , Maranhão Arthur Oliveira 
Published: February 2025

Diabetes mellitus tipo 2 (DM2) e insuficiência cardíaca (IC) são comorbidades frequentemente presentes em idosos. O DM2 é um dos principais fatores de risco para doenças cardiovasculares, sendo a IC uma das principais consequências. A coexistência de ambas as condições é associada a prognósticos desfavoráveis e aumento de mortalidade quando comparada à presença isolada de uma delas. Assim, recentemente, estudos têm intensificado o enfoque na conexão entre DM2 e IC, dada sua importância clínica e epidemiológica. O objetivo deste estudo é determinar a prevalência e os fatores associados à IC em indivíduos brasileiros com mais de 50 anos, levando em consideração a presença ou não de DM2. Em formato transversal descritivo, utilizou-se dados provenientes do Estudo Longitudinal de Saúde do Idoso (ELSI - Brasil) coletados entre os anos de 2019 e 2021. Foi avaliada a prevalência de IC na população com DM2 em comparação com a população sem diabetes. Assim, os participantes foram divididos em dois grupos: pacientes com IC e DM2 e pacientes com IC sem DM2. Esses grupos foram analisados e comparados entre si. A análise dos dados foi executada por meio de testes de associação e regressão logística. Diabetes está associado à insuficiência cardíaca (χ²=54,62; p<0,001) e a chance de se observar um caso de insuficiência cardíaca entre aqueles indivíduos com diabetes é 2,18 (IC 95%: 1,76 a 2,69) vezes maior do que entre aqueles indivíduos que não possuem diabetes.
Padrão de Aslanger – relato de caso
Authors: Júnior Luís Máximo de Araújo , Oliveira Danyel Augusto Sousa Castro , Ibrahim Bruno Fouad , Bruno Marcelo Hueb Cecilio Naves , Cunha Pedro Henrique Borges da , Sousa Rodrigo Cunha 
Published: February 2025

Na literatura médica vigente, o principal pilar do diagnóstico de oclusão coronariana aguda é a identificação ou exclusão precoce do padrão eletrocardiográfico do tipo supradesnivelamento do segmento ST (IAMCSST) em duas ou mais paredes contíguas. Entretanto, existem outros padrões eletrocardiográficos que indicam a presença de obstrução coronariana aguda, sendo um deles descrito por Aslanger, et al (2020). Este artigo tem como objetivo incitar a discussão do diagnóstico de oclusão coronariana aguda, através deste relato de caso de uma paciente de 61 anos que apresentou quadro de dor precordial e um padrão eletrocardiográfico compatível com o descrito por Aslanger. Discussão está que se faz importante visto que quando presente este padrão associado a quadro clínico suspeito de síndrome coronariana aguda, necessita-se de reperfusão de emergência, sendo fundamental este conhecimento a todos os médicos para diagnosticar e tratar esse evento, contribuindo para reduzir a morbimortalidade associada a esta moléstia.
Conhecendo e Cuidando: capacitação de professores no manejo da epilepsia em ambientes educacionais
Authors: Cunha Alice Cristina Souza , Magalhães Sabrina Alaíse Linhares , Nascimento Abraão Martins do , Neiva Ana Lara Sucupira de Matos , Souza Hellen Santos Novas , Luz Iani Soares , Santos Ketelly Costa , Nogueira Paloma Souza , Meira Viviane Fernanda da Silva , Silva Rafael Correia de Sousa da , Oliveira Cristina da Costa 
Published: February 2025

Os transtornos neurológicos, como a epilepsia, comprometem funções motoras e cognitivas, impactando a qualidade de vida do indivíduo acometido, sobretudo devido ao grau de desinformação da sociedade. A ausência de conhecimento adequado, especialmente entre educadores, pode levar a condutas incorretas durante crises epilépticas, aumentando os riscos. A capacitação no manejo correto durante crises epilépticas é essencial para a redução dos danos e a promoção da inclusão dos discentes acometidos. Nesse sentido, objetiva-se descrever a aplicação de um programa de capacitação destinado a professores de escolas de ensino fundamental e médio, com o intuito de aprimorar a compreensão sobre a epilepsia e fortalecer a habilidade no manejo adequado de crises epilépticas. Dessa forma, realizou-se duas palestras teórico-práticas para docentes de colégios públicos, nos meses de outubro e novembro de 2024, utilizando materiais didáticos para abordagem das condutas adequadas diante de uma crise epiléptica. Como resultados, obteve-se a participação de nove docentes na primeira palestra e vinte docentes na segunda palestra, os quais demonstraram interesse em relação à temática abordada, explanaram suas dúvidas e simularam o atendimento a um indivíduo em crise epiléptica.
Clinical repercussions after liberal volume replacement in the intraoperative period of cancer patients in a Hospital Unit in the Amazon
Authors: Montejo Mariam Lidemys Marin , Barroso André Renato Moura , Marques Antônio Roberto , Pitoli Caroline Olinda de Souza , Junior Donn-Thell Frewyd Sawntzy , Said Gaya Amanda , Gonçalves Iannca Hama Torres Araújo , Fernandes Renata Larissa de Araujo , Pimentel Ivandete Pereira , Cardoso Mirlane Guimarães de Melo 
Published: February 2025

During the perioperative period, intravascular volume management becomes crucial to achieve better postoperative outcomes. Maintenance of euvolemia is critical to ensure adequate tissue perfusion, since hypervolemia has been associated with higher rates of postoperative morbidity. One of the main challenges in managing surgical volume lies in intravascular monitoring. Despite the use of essential tools such as non-invasive blood pressure cuffs and heart rate monitoring, significant challenges persist due to difficulties in accurately measuring fluid losses, varied cardiovascular responses to anesthesia, and the absence of standardized assessment protocols for anesthetized patients. Given the critical role of adequate volume replacement in cancer patients undergoing medium-sized urologic surgeries, this study aims to identify potential adverse clinical consequences associated with volume replacement therapy in postoperative ICU patients undergoing radical prostatectomy and radical nephrectomy in an oncology referral center in the Brazilian Amazon. This prospective, descriptive and exploratory study will be carried out from August 2023 to August 2024 at the Amazonas Oncological Control Center Foundation (FCECON). The research seeks to elucidate specific adverse clinical outcomes related to fluid management in cancer patients undergoing these surgical procedures.
ANALISIS FAKTOR-FAKTOR YANG MEMPENGARUHI ANGKA TUBERKULOSIS DI PROVINSI JAWA TENGAH DENGAN PENDEKATAN REGRESI NONPARAMETRIK SPLINE TRUNCATED
Authors: Sinta Widarti  , Kris Suryowati  , Rokhana Dwi Bekti  
Published: February 2025

Tuberkulosis merupakan penyakit infeksi kronik dan menular yang erat kaitannya dengan keadaan lingkungan dan perilaku masyarakat yang disebabkan oleh bakteri Mycobacterium tuberculosis. Penelitian ini dilakukan di Jawa Tengah dikarenakan di provinsi ini termasuk peringkat ketiga banyaknya kasus tuberkulosis di Indonesia pada tahun 2022 yaitu sebesar 77.426 kasus dan kurangnya penelitian yang dilakukan di provinsi ini. Faktor-faktor yang diduga mempengaruhi angka kasus tuberkulosis yaitu persentase rumah tangga yang memiliki akses terhadap sanitasi layak, persentase penduduk miskin, persentase penduduk usia 15 tahun ke atas yang merokok, Indeks Pembangunan Manusia, dan persentase penduduk yang memiliki jaminan kesehatan. Penelitian ini bertujuan untuk menganalisis faktor-faktor yang mempengaruhi angka kasus tuberkulosis di Jawa Tengah menggunakan Regresi Nonparametrik Spline Truncated. Metode ini digunakan karena pola hubungan antara kasus tuberkulosis dengan faktor faktor yang diduga mempengaruhinya tidak mengikuti pola tertentu. Hasil penelitian menunjukkkan bahwa model regersi nonparametrik spline truncated terbaik adalah menggunakan 3 titik knot dengan nilai GCV minimum yaitu 7051,75, nilai MSE sebesar 2326,96, dan empat variabel berpengaruh signifikan yaitu persentase rumah tangga yang memiliki akses terhadap sanitasi layak, persentase penduduk miskin, persentase penduduk usia 15 tahun ke atas yang merokok, dan Indeks Pembangunan Manusia. Koefisien determinasi dari model sebesar 96,60%.