bluuebunny/crossref_metadata_2025_split huggingface dataset:
Erythema multiforme after application of aural Gentisone HC drops
Authors: Siddiq M. A. 
Published: November 2007

AbstractErythema multiforme is an uncommon acute self-limiting condition characterized by mucocutaneous lesions of varying severity with a variable pattern of recurrence. This is a case of a four-year-old girl who developed erythema multiforme secondary to topical aural application of Gentisone HC drops (hydrocortisone acetate one per cent, gentamicin 0.3 per cent (as sulphate)) prescribed as a treatment for otorrhoea following grommet insertion. The clinical features are described and the literature reviewed. To my knowledge, this is the first reported case in the literature, of erythema multiforme secondary to a topical aminoglycoside/steroid preparation.
Delayed deterioration of hearing following bacterial meningitis
Authors: Jayarajan V. , Rangan S. 
Published: November 2007

AbstractBacterial meningitis is an important cause of acquired sensorineural deafness in childhood. Deafness following meningitis may be progressive. Previous reports have shown deterioration in hearing up to 12 years after the illness. We present two cases of sensorineural deafness following meningitis. Severe to profound sensorineural hearing losses were detected immediately after meningitis in these patients. The hearing subsequently deteriorated in both cases. Deterioration in hearing thresholds occurred 17 years after the illness in one case. In the other patient the hearing got progressively worse three years after meningitis. She subsequently required a cochlear implant.
Imaging for cochlear implants
Authors: Phelps P. D. , Proops D. W. 
Published: November 2007

AbstractAll patients in the Birmingham Cochlear Implant Programme underwent computerized tomography (CT) scanning and were assessed and images interpreted by the main author. Of the first 100 cases, 20 were considered to have abnormalities of the inner ears by CT imaging. It is concluded that the commonest abnormality was cochlear otospongiosis followed by labyrinthitis ossificans.Otospongiosis is well shown by CT which gives a good predicator of luminal patency.However, labyrinthus obliterans, although usually apparent on CT, is not reliably shown in all cases and T2 weighted magnetic resonance imaging (MRI) is better.
Rhabdomyosarcoma of the maxillary sinus
Authors: Suzuki M. , Kobayashi Y. , Harada Y. , Kyo T. , Dohy H. , Kuramoto A. , Etoh R. 
Published: November 2007

AbstractA rare case of adult rhabdomyosarcoma originating from the left maxillary sinus is reported. A 22-year-old Japanese woman was referred to the Department of Otolaryngology, Hiroshima University, for investigation of the primary source of a metastatic tumor in the bone marrow. An X-ray of the sinuses revealed a tumor in the left maxillary sinus with extension into the nasal cavity, ethmoidal and sphenoidal sinuses. The patient was managed with a chemotherapeutic regimen consisting of high-dose methotrexate, adriamycin, vincristine, cyclophosphamide and prednisolone. After three courses of this chemotherapy, the tumor had decreased in size by about 90 per cent, as indicated by X-rays. The remaining tumor was removed by an extended Denker's operation. Following the surgery another seven courses of chemotherapy were given and during the eight months following the operation the patient has been free from any local recurrence.
Tympanometric findings in patients with adenoid hyperplasia, chronic sinusitis and tonsillitis
Authors: Alhady Rashad Abd , Sharnoubi M. EL 
Published: November 2007

AbstractTympanograms were done on 120 patients with adenoid hyperplasia, chronic sinusitis and chronic tonsillitis to measure the middle-ear pressure as a parameter to eustachian tube function. The results were compared with those obtained in 50 normal subjects. The statistical significance of the mean values of middle-ear pressure is very highly significant in patients with adenoid hyperplasia, significant in chronic sinusitis group and insignificant in patients with chronic tonsillitis, as compared to the normal control group. Hence, eustachian tube dysfunction is maximum in patients with obstructing adenoids, less in chronic sinusitis and least in chronic tonsillitis.
Management of middle-ear effusions in children
Authors: Hughes K. B. 
Published: November 2007

SummaryA double-blind placebo controlled trial of Mucodyne (carbocisteine, Berk Pharmaceuticals), Actifed (triprolidine HCI and pseudoephedrine HCI, Wellcome) and combined Mucodyne and Actifed in the treatment of middle-ear effusions is reported. The trial was undertaken to assess whether either preparation, alone or in Combination, would reduce the number of children requiring surgical treatment for this condition. No statistical difference between the various groups in avoiding surgical treatment with Mucodyne was associated with a significantly greater number of ears restored to a normal appearance and middle ear function as measured by tympanometry. All patients relapsing after surgery belonged to the groups receiving placebo, Actifed or the combination of Mucodyne and Actifed prior to the operation.
Near-drowning, scuba diving
Authors: Rubin Allan M. , Blair Robin L. , Alberti Peter W. 
Published: November 2007

AbstractThis case report illustrates an unusual hazard of underwater sports: vagal neuropathology secondary to early poliomyelitis which resulted in residual palato-pharyngeal paresis. Gag and swallowing reflexes appeared to function adequately but in fact were not normal. When stressed, during water aspiration, they were inadequate, resulting in great risk to the underwater enthusiast. A history of early viral myelitis must be considered as a potential hazard in underwater sports.
Erythromycin in the treatment of Otitis Media with Effusion(OME)
Authors: Ernstson S. , Sundberg L. 
Published: November 2007

SummaryPrevious studies havd shown erythromycin to penetrate into both the middle-ear effusion and the adenoid tissue in children with Otitis Media with Effusion (OME). The levels obtained were similar to the plasma levels. Cultures in long-standing cases of OME have yielded respiratory pathogens—Haemophilus influenzae, streptococcus pneumoniae and Branhamella catarrhalis—in the nasopharynx in 79 per cent and in the middle-ear effusion in per cent.In the present investigation a group of children with OME of more than three months' duration were given erythromycin (Abboticin®) in standard dosage for the last 10 days prior to scheduled operation (paracentesis or tympanostomy). Resolution was determined as normalization of the middle ear status, and this led to cancellation of surgery. The rate of resolution—12/26 (45 per cent)—was significantly higher than in a similar group of children not treated with erythromycin—11/72 (15 per cent). There are thus rational reasons for using erythromycin in OME, in many cases as an alternative to tympanostomy.
Osteosclerotic Plasmacytoma of maxillary bone (orbital floor)
Authors: Mustone Thomas A. , Fried Marvin P. , Goodman Max L. , Kelly James H. , Strome Marshall 
Published: November 2007

AbstractPlasma cell neoplasms have been classified as multiple myeloma, solitary plasmacytoma and extramedullary plasmacytoma. They are usually considered as osteolytic lesions of bone except for the rare occurrence of osteosclerotic lesions. This paper describes the first reported osteosclerotic plasmacytoma of the maxillary bone and orbital floor. The difficulties in establishing a diagnosis and the relationship to other plasma cell neoplasms are discussed.Osteosclerotic plasmacytomas are a rare variant of plasma cell tumors which usually produce osteolytic lesions rather than bony sclerosis. Sixty-eight patients with the osteosclerotic variant have appeared in the world literature, with an overall incidence of about 1 per cent in a large series of plasma cell neoplasms (Dreidger and Pruzanski, 1979). There have been only six previous cases of solitary osteosclerotic plasmacytomas reported (Morley and Schweiger, 1964; Roberts et al., 1974; Rodriguez et al. 1976; Rushton, 1965; Schneinker, 1938; Brigham Medical Review, 1961) involving spine, sternum, or rib. None have previously been reported in the head and neck area.Plasma cell tumors have been classified into multiple myeloma, solitary plasmacytomas of bone, and extramedullary plasmacytomas. Multiple myeloma is a disseminated plasma cell
malignancy characterized by the production of homogeneous immunoglobulins (whole or fragments) which appear in the serum and urine. Plasma cell tumors can also occur as solitary plasmacytomas, usually in bone, but also in soft tissue. With time, most solitary plasmacytomas develop disseminated disease with all the characteristics of multiple myeloma (Wiltshaw, 1976). Extramedullary plasmacytomas arise in soft tissue rather than bone, and primarily occur in the head and neck region. Clinically, they remain localized and less frequently develop into disseminated myeloma.
Diagnostic imaging of the nose and paranasal sinuses
Authors: Lloyd G. A. S. 
Published: November 2007

AbstractThere are four principal modalities now used by the Radiologist to investigate the nose and paranasal sinuses. These are: plain X-ray, conventional tomography, computerised tomography (CT), and magnetic resonance (MR). Plain X-ray is the initial examination, and is used as a screening procedure before employing one of the tomographic techniques. Conventional pluridirectional tomography has now been superseded by CT scannning, which has the advantage of providing both good bone detail and soft tissue imaging. Since the introduction of magnetic resonance (MR), this technique has replaced CT as the optimum method of showing the extent of soft tissue tumour in the sinuses. The introduction of the paramagnetic contrast agent Gadolinium (Gd DTPA) has improved its accuracy. In the anterior fossa discrimination between cerebral oedema and tumour invasion is better shown, and in the sinuses tumour is more easily identified from retained secretion and inflamed mucosa. The best method currently available to show pathology in the nose and sinuses is a combination of GdMR and CT: the former to identify the soft tissues and the latter to show bone changes.
Antroscopic study of the maxillary antrum in lepromatous leprosy
Authors: Soni N. K. 
Published: November 2007

AbstractThe technique of antroscopy affords an accurate assessment of chronic sinus disease. It was performed in twelve patients suffering from lepromatous leprosy in order to determine the type, nature and site of the lesion. Antral involvement with lepromatous leprosy may begin with a localized area of erythema progressing to granuloma formation or ulceration. The antero-inferior part of the antrum is the most commonly affected site.
Unusual presentation of neurilemmoma in the cerebellopontine angle
Authors: De S. K. , Basu A. 
Published: November 2007

AbstractAn unusual presentation of a neurilemmoma in the cerebellopontine (CP) angle is reported. The tumour was localised in the CP angle and the case presented with post-auricular swelling and erosion of the squamous part of temporal bone without involvement of the auditory or other cranial nerves.
Recovery from sensorineural deafness in Wegener's granulomatosis
Authors: Clements M. R. , Mistry C. D. , Keith A. O. , Ramsden R. T. 
Published: November 2007

AbstractWegener's granulomatosis may present with deafness or other aural symptoms. This report describes two patients with histological evidence of Wegener's granulomatosis who developed reversible sensorineural hearing loss during the course of their illness. The first patient showed complete recovery of a sensorineural hearing loss averaging 50 dB after ten months treatment with cyclophosphamide and high-dose prednisolone. The second patient, who was on maintenance haemodialysis, achieved a 40 dB improvement in sensorineural hearing loss within two weeks of adding cyclophosphamide to pre-existing corticosteroid therapy. These findings suggest that the prognosis of sensorineural hearing loss in Wegener's granulomatosis can be improved with suppression of the vasculitic process by early treatment with combined cytotoxic-immunosuppressive therapy
Isolated sphenoiditis: A diagnostic problem
Authors: Urquhart A. C. , Fung G. , McIntosh W. A. 
Published: November 2007

AbstractA case of primary isolated sphenoiditis that developed cavernous sinus thrombosis is presented. It is difficult to diagnose and patients are often not seen initially by an ENT surgeon, making it more important for other branches of medicine to be aware of this condition. We discuss isolated sphenoiditis with particular reference to the diagnosis, management and complications of this condition
The effect of botulinum toxin type A injection for intrinsic rhinitis
Authors: Kim Kyung-Su , Kim Sung-Shik , Yoon Joo-Heon , Han Jae Wook 
Published: November 2007

AbstractBotulinum toxin type A (BTA) is known to inhibit the release of acetylcholine from cholinergic nerve endings. Owing to the characteristics of BTA, we thought that it could be used for the treatment of intrinsic rhinitis acting as an anticholinergic drug. In a double-blind placebo-controlled study four units of BTA were injected into the middle turbinate (two units) and inferior turbinate (two units) in each nasal cavity. Rhinorrhoea, nasal obstruction, and sneezing were recorded in a symptom diary on the basis of a scale of 5 and the number of paper tissues used per day was also recorded for 24 weeks. Rhinorrhoea was significantly diminished in severity (24.1–41.5 per cent reduction) and paper tissue use (54.3 per cent reduction) in the BTA group compared with the placebo group. This effect could be maintained for four weeks. Sneezing and nasal stuffiness were not affected by BTA. These results suggest that BTA can be used to treat rhinorrhoea in intrinsic rhinitis patients, however, the effective period is short.
Second primary cancer of the larynx in patients with lung cancer
Authors: Talmi Yoav P. , Bedrin Lev , Waller Alexander , Horowitz Zeev , Skurnik Yair , Adunski Abraham , Kronenberg Jona 
Published: November 2007

AbstractSynchronous or metachronous second primary malignancies of the lung are sometimes encountered in patients with laryngeal cancer while the occurrence of a laryngeal second primary following cancer of the lung is rare.A two-armed study was conducted. A prospective arm in which the larynges of 56 terminal lung cancer patients were examined, and a retrospective arm incorporating both a chart study of 126 terminal head and neck cancer patients (HNCP) and a computerized search of all hospital records of patients with laryngeal and lung cancers. No laryngeal malignancy was found in the lung cancer patients' group and no antedating pulmonary malignancy was recorded in the terminal HNCP. The computerized search of 1778 lung cancer patients and 213 laryngeal cancer patients also failed to demonstrate cases where the former preceded the latter.In conclusion. No second primary of the larynx was found in lung cancer patients. These results compare with reports of large databases where cancer of the larynx was found in a negligible percentage of lung cancer survivors and theories explaining this are discussed.
Malignant otitis externa with optic neuritis
Authors: Bath A. P. , Rowe J. R. , Innes A. J. 
Published: November 2007

AbstractMalignant otitis externa is a serious condition that presents difficulties in treatment, and also in monitoring its progress. A case of malignant otitis externa with optic neuritis is presented that remained refractory to standard treatment but was cured by adjuvant hyperbaric oxygen therapy. This is the only reported case that has survived this disease with optic neuritis. The usefulness of imaging techniques in this condition is discussed, as well as the ESR, in evaluating the effectiveness of treatment.
Ethmoid metastasis of endometrial carcinoma causing mucocoele of maxillary antrum
Authors: Scott A. , Raine M. , Stansbie J. M. 
Published: November 2007

AbstractWe report a case of an antral mucocoele secondary to the obstruction of its ostium by metastatic endometrial carcinoma. This is the first report of such a cause for a mucocoele, and for a metastasis from such a tumour in the head and neck.
DNA flow cytometry of acinic cell carcinomas of major salivary glands
Authors: El-Naggar Adel K. , Batsakis J. G. , Luna Mario A. , McLemore Donia , Byers R. M. 
Published: November 2007

AbstractFifteen acinic cell carcinomas from an equal number of patients were analysed for their DNA content and proliferative (S-phase) index by flow cytometry from archival tissues. Seven of the carcinomas manifested a diploid DNA content. None of the patients with diploid acinic cell carcinomas died of their carcinomas and none developed metastases in follow-up periods extending for 10 or more years. Four of eight patients with aneuploid acinic cell carcinomas have died because of their malignancies within a 10 year period after the first surgical removal of the carcinoma. Five of the eight patients exhibited metastases. Although the number of cases does not permit strong correlations between histopathological features, abnormalities in DNA content and outcome of patients, it was noted that carcinomas with prominent necrosis, tubulo ductal differentiation and ‘dedifferentiated’ areas displayed more aggressive biological courses.
Intranasal adhesions which recur despite splinting: an ominous sign?
Authors: Watson M. G. , Marshall H. F. 
Published: November 2007

AbstractIntranasal adhesions are a common complication following nasal surgery. They may be prevented by the use of silastic splints, which are also a very effective treatment for established lesions. We report a patient where intranasal adhesions rapidly recurred despite the use of splints, who was found to be suffering from Wegener's granulomatosis.
A momentary assessment study of the reputed emotional phenotype associated with borderline personality disorder
Authors: Glaser J.-P. , Os J. Van , Mengelers R. , Myin-Germeys I. 
Published: November 2007

SUMMARYBackgroundStress is postulated to play an essential role in the expression of core borderline symptoms. However, the phenomenology of stress reactivity in borderline personality disorder remains unclear. The current study investigated the phenomenology of stress sensitivity in borderline personality disorder in the flow of daily life and compared this with stress sensitivity in patients suffering from psychotic disorders, a group so far known to report the largest reactivity to stress.MethodA total of 44 borderline patients, 42 patients with psychotic disorder and 49 healthy controls were studied with the Experience Sampling Method (a structured diary technique assessing current context and mood in daily life) to assess: (1) appraised subjective stress related to daily events and activities; and (2) emotional reactivity conceptualized as changes in positive and negative affect.ResultsMultilevel regression analysis revealed that subjects with borderline personality disorder experienced significantly more emotional reactivity to daily life stress compared with both patients with psychosis and healthy controls, as evidenced by a larger increase in negative affect and a larger decrease in positive affect following stress.ConclusionThese results are the first to ecologically validate the incorporation of stress reactive symptoms in the diagnosis of borderline personality disorder. Borderline patients continually react stronger than patients with psychosis and healthy controls to small disturbances that continually happen in the natural flow of everyday life. Altered emotional stress reactivity may define borderline personality disorder.
The technological era of ‘sound’: a challenge for musicology and a new range of social practices
Authors: Delalande François 
Published: November 2007

AbstractThe ‘technological revolution’ that took place in music during the twentieth century is equivalent to the revolution that took place between the twelfth and fourteenth century, which transformed musical notation into applications of technology related to creation. This second revolution, as well as the first one, concerns not only musical form, but also the social organisation related to music. The aesthetic of sound is the key factor (in all the genres of contemporary music), which is a major challenge for musical analysis. Society is reorganising itself, favouring the appropriation and amateur practices within musical creation. Musical research institutions – and particularly the GRM – develop new forms of collaboration with their audience and contribute to the constitution of a ‘horizontal’ society, based on exchange, in frank opposition with the ‘vertical’ society, based on a reduced number of producers and a large amount of consumers.
Nature and the GRM
Authors: Thomas Jean-Christophe 
Published: November 2007

AbstractIt is a habit to invoke Aristotle when dealing, within the arts, with ‘Nature’ – that the Man–Artist (and not only the musician) would be, he says, ‘inclined’ to imitate. It is true, the history of music clearly attests to the temptation and of the ‘pleasure’ (as Aristotle also says) found in mimesis. We know that very lately in history musique concrète gives a new perspective to this question as well as to other questions, and changes the deal: because the sound objects of the world, of the whole world – the ‘noises’ – that needed to be imitated, can now be easily captured through technology, almost in a photographic way, and then they can be gathered, kept, and finally be composed. Hopefully Pierre Schaeffer, its genial inventor, has, concerning the question of nature within new music, a position that tears him apart, which is paradoxical, uncomfortable, fundamental: that the nature that is so easily captured, he does not want to exhibit; to understand the lessons, the hidden musical lessons, he only wants to examine it. This almost heroic model will only be partially followed by the composers (concrète, electroacoustic, acousmatic, anecdotical composers) who have been working during the last sixty years in this passionate domain. At the end of this article, the sketch of a typology, based on musical examples, tries to clarify the way nature is dealt with, when it appears in musique concrète.
A Perceptual Correlate of the Labial-Coronal Effect
Authors: Sato Marc , Vallée Nathalie , Schwartz Jean-Luc , Rousset Isabelle 
Published: November 2007

PurposeStatistical studies conducted in various languages on both infants and adults have revealed an intersyllabic preference for initiating words with a labial consonant–vowel–coronal consonant sequence. Speech motor constraints have been proposed to explain this so-calledlabial-coronal effect. This study was designed to test for a possible perceptual correlate of the labial-coronal effect in French adults.MethodThe authors examined the perceptual stabilities of repeatedly presented disyllabic sequences, involving either a labial-vowel–coronal-vowel (LC) or a coronal-vowel–labial-vowel (CL) phonological structure. With this aim, they exploited theverbal transformation effect,which refers to the perceptual changes experienced while listening to a speech form cycled in rapid and continuous repetition. Two experiments were carried out, involving either voiced or unvoiced plosive consonants.ResultsIn both experiments, a greater stability and attractiveness was observed for LC stimuli, which suggests that in a (…)LCLC(…) flow, the listener could more naturally provide a segmentation into LC chunks.ConclusionThis study demonstrates that the labial-coronal effect also occurs in the course of online speech processing. This result is interpreted in relation with theories assuming a link between perception and action in the human speech processing system.