bluuebunny/crossref_metadata_2025_split huggingface dataset:
Placement into Scattered-Site or Place-Based Permanent Supportive Housing in Los Angeles County, CA, During the COVID-19 Pandemic
Authors: Henwood Benjamin F. , Kuhn Randall , Gonzalez Amanda Landrian , Chien Jessie , Tu Yue , Bluthenthal Ricky , Cousineau Michael , Padwa Howard , Ijadi-Maghsoodi Roya , Chinchilla Melissa , Smith Bikki Tran , Gelberg Lillian 
Published: March 2024

AbstractThere are two dominant approaches to implementing permanent supportive housing (PSH), namely place-based (PB) and scattered-site (SS). Formal guidance does not distinguish between these two models and only specifies that PSH should be reserved for those who are most vulnerable with complex health needs. To consider both system- and self-selection factors that may affect housing assignment, this study applied the Gelberg-Anderson behavioral model for vulnerable populations to compare predisposing, enabling, and need factors among people experiencing homelessness (PE) by whether they were assigned to PB-PSH (n = 272) or SS-PSH (n = 185) in Los Angeles County during the COVID-19 pandemic. This exploratory, observational study also included those who were approved but did not receive PSH (n = 94). Results show that there are notable differences between (a) those who received PSH versus those who did not, and (b) those in PB-PSH versus SS-PSH. Specifically, PEH who received PSH were more likely to be white, US-born, have any physical health condition, and have lower health activation scores. PEH who received PB- versus SS-PSH were more likely to be older, Black, have any alcohol use disorder, and have higher health activation scores. These findings suggest that homeless service systems may consider PB-PSH more appropriate for PEH with higher needs but also raises important questions about how race may be a factor in the type of PSH that PEH receive and whether PSH is received at all.
Social Diversity on Corporate Boards in a Country Torn by Civil War
Authors: Nazliben Kamil K. , Renneboog Luc , Uduwalage Emil 
Published: March 2024

AbstractWe examine how social diversity and inclusiveness on corporate boards affect corporate performance and monitoring in Sri Lanka, a country subject to decades of polarization, civil war, and even genocide. Barely more than a decade after the civil war, we find that board social diversity on the basis of ethnicity, religion, language, gender, and nationality of the board members is positively related to corporate performance, both in terms of stock market performance and accounting returns, and to corporate financial stability. The main positive effects of social diversity derive from ethno-linguistic inclusiveness. The results are confirmed by an instrumental variable approach that addresses endogeneity issues. We find no evidence that inter-personal and moral conflicts or communication problems among board members negatively affect firm performance.
Reaching the Unreachable: Intensive Mobile Treatment, an Innovative Model of Community Mental Health Engagement and Treatment
Authors: Colton Jana , Misra Roshni , Woznick Elise , Wiedermann Rachel , Huh Anna 
Published: March 2024

AbstractIn this paper we introduce the Intensive Mobile Treatment (IMT) model, which arose from a 2016 New York City initiative to engage individuals who were “falling through the cracks” of the mental health, housing, and criminal justice systems. People who are referred to IMT often have extensive histories of trauma. They experience structural racism and discrimination within systems and thus can present as distrustful of treatment teams. We detail the structure of the program as we practice it at our non-profit agency and outline the psychodynamic concepts that inform our work with challenging populations. We acknowledge IMT’s role in engaging in advocacy and addressing social justice in our work. We also discuss how through this model we are able to both mitigate and tolerate risk in participants with difficult-to-manage behaviors. This is typically a long-term, non-linear process. We address how this impacts the team dynamic as a whole and explain how with long-term, trusting therapeutic relationships, participants can change and grow over time. We also explain the ways in which our non-billing model plays an integral role in the treatment we are able to provide and identify several challenges and areas for program growth. In outlining our model and its methodology, we hope to empower other practitioners to adapt IMT to other settings beyond the New York City area.
Low expression of NR1D1 and NR2E3 is associated with advanced features of retinoblastoma
Authors: Ding Jie , Sun Jie , Ma Rui-Qi , Zheng Ke , Han Yi-Nan 
Published: March 2024

Abstract
Purpose
To investigate the expression of nuclear receptor subfamily 1 group D member 1 (NR1D1) and nuclear receptor subfamily 2 group E Member 3 (NR2E3) in retinoblastoma (RB) and their correlation with the clinical and pathological features of RB.

Methods
Immunohistochemical (IHC) assays were performed to detect and evaluate the expression levels of NR1D1 and NR2E3 in paraffin-embedded tissue samples. The relationship between the expression levels and clinicopathological characteristics of RB patients was analyzed using the χ2 test or Fisher exact test.

Results
A total of 51 RB patients were involved in this research. The expression levels of NR1D1 (P = 0.004) and NR2E3 (P = 0.024) were significantly lower in RB tumor tissues than in normal retina. The expression levels of NR1D1 and NR2E3 were less positive in RB patients with advanced stages (P = 0.007, P = 0.015), choroidal infiltration (P = 0.003, P = 0.029), and optic nerve infiltration (P = 0.036, P = 0.003). In addition, a low expression level of NR2E3 was associated with high-risk pathology (P = 0.025) and necrosis (P = 0.035) of RB tissues.

Conclusion
The expression levels of NR1D1 and NR2E3 were decreased in RB and closely associated with the clinical stage and high invasion of the disease. These findings provide new insights into the mechanism of RB progression and suggest that NR1D1 and NR2E3 could be potential targets for treatment strategies.
Geometric stress functions, continuous and discontinuous
Authors: Baranyai Tamás 
Published: March 2024

AbstractIn his work on stress functions Maxwell noted that given a planar truss the internal force distribution may be described by a piecewise linear, $$C^0$$

C
0

continuous version of the Airy stress function. Later Williams and McRobie proposed that one can consider planar moment-bearing frames, where the stress function need not be even $$C^0$$

C
0

continuous. The two authors also proposed a discontinuous stress function for the analysis of space-frames, which however suffers from incompleteness. This paper provides a discontinuous stress function for n-dimensional space frames that is complete and minimal, along with its derivation from an n-dimensional continuous stress function. The continuous stress function generalizes both Günther’s and Maxwell’s stress functions.
Rodolfo Sacco’s Legacy: Insights from a Young Scholar
Authors: Bergomi Caterina 
Published: March 2024

AbstractThis article aims to demonstrate the enduring impact of Rodolfo Sacco’s influential contributions to comparative law on the perspectives of young scholars. It explores two pivotal aspects of his research that continue to significantly influence the work of a young scholar—the theory of legal formant and exploration of the relationship between law and language. The article also briefly highlights the relevance of legal comparison in the contemporary European legal context.
Unveiling the interplay of psychological capital, family business, and gender on firm performance during COVID-19
Authors: Lanchimba Cintya , Welsh Dianne H.B. , Kaswengi Joseph 
Published: March 2024

AbstractThis study examines the complex relationships between Psychological Capital, family business, ownership, gender, and firm performance during the COVID-19 pandemic. The study examines the effects of these variables on firm performance and explores the empirical interaction effects. The findings reveal that Psychological Capital positively influences firm performance, supporting the hypothesis that owners with higher Psychological Capital contribute to better business outcomes. Additionally, family business and ownership significantly impact firm performance, indicating that family involvement and concentrated ownership drive organizational success. Surprisingly, the results indicate a negative impact of gender on firm performance, suggesting that firms managed by women are perceived as less successful. The study also explores the interaction effects and finds that the positive relationship between Psychological Capital and firm performance is amplified in family businesses. However, gender does not moderate this relationship, indicating that women Owners face challenges in translating their Psychological Capital into firm performance in the emerging economy of Ecuador. The results provide insights into the complex dynamics within family businesses and underline the need to address gender disparities and promote inclusive Ownership practices. Implications are discussed.
A new double inertial subgradient extragradient algorithm for solving split pseudomonotone equilibrium problems and fixed point problems
Authors: Mebawondu A. A. , Ofem A. E. , Akutsah F. , Agbonkhese C. , Kasali F. , Narain O. K. 
Published: March 2024

AbstractThe purpose of this article is to suggest a modified subgradient extragradient method that includes double inertial extrapolations and viscosity approach for finding the common solution of split equilibrium problem and fixed point problem. The strong convergence result of the suggested method is obtained under some standard assumptions on the control parameters. Our method does not require solving two strongly convex optimization problems in the feasible sets per iteration, and the step-sizes do not depend on bifunctional Lipschitz-type constants. Furthermore, unlike several methods in the literature, our method does not depend on the prior knowledge of the operator norm of the bounded linear operator. Instead, the step-sizes are self adaptively updated. We apply our method to solve split variational inequality problem. Lastly, we conduct some numerical test to compare our method with some well known methods in the literature.
5-chloro-3-(2-(2,4-dinitrophenyl) hydrazono)indolin-2-one: synthesis, characterization, biochemical and computational screening against SARS-CoV-2
Authors: Majoumo-Mbe Felicite , Sangbong Neba Abongwa , Tadjong Tcho Alain , Namba-Nzanguim Cyril T. , Simoben Conrad V. , Eni Donatus B. , Alhaji Isa Mustafa , Poli Adi Narayana Reddy , Cassel Joel , Salvino Joseph M. , Montaner Luis J. , Tietjen Ian , Ntie-Kang Fidele 
Published: March 2024

AbstractChemical prototypes with broad-spectrum antiviral activity are important toward developing new therapies that can act on both existing and emerging viruses. Binding of the SARS-CoV-2 spike protein to the host angiotensin-converting enzyme 2 (ACE2) receptor is required for cellular entry of SARS-CoV-2. Toward identifying new chemical leads that can disrupt this interaction, including in the presence of SARS-CoV-2 adaptive mutations found in variants like omicron that can circumvent vaccine, immune, and therapeutic antibody responses, we synthesized 5-chloro-3-(2-(2,4-dinitrophenyl)hydrazono)indolin-2-one (H2L) from the condensation reaction of 5-chloroisatin and 2,4-dinitrophenylhydrazine in good yield. H2L was characterised by elemental and spectral (IR, electronic, Mass) analyses. The NMR spectrum of H2L indicated a keto–enol tautomerism, with the keto form being more abundant in solution. H2L was found to selectively interfere with binding of the SARS-CoV-2 spike receptor-binding domain (RBD) to the host angiotensin-converting enzyme 2 receptor with a 50% inhibitory concentration (IC50) of 0.26 μM, compared to an unrelated PD-1/PD-L1 ligand–receptor-binding pair with an IC50 of 2.06 μM in vitro (Selectivity index = 7.9). Molecular docking studies revealed that the synthesized ligand preferentially binds within the ACE2 receptor-binding site in a region distinct from where spike mutations in SARS-CoV-2 variants occur. Consistent with these models, H2L was able to disrupt ACE2 interactions with the RBDs from beta, delta, lambda, and omicron variants with similar activities. These studies indicate that H2L-derived compounds are potential inhibitors of multiple SARS-CoV-2 variants, including those capable of circumventing vaccine and immune responses.
Performance assessment of up-flow anaerobic multi-staged reactor followed by auto-aerated immobilized biomass unit for treating polyester wastewater, with biogas production
Authors: Hassan Raouf , Kriaa Karim , Wahaballa Amr M. , Elsayed Mahmoud , Mahmoud M. , Nasr Mahmoud , Tawfik Ahmed 
Published: March 2024

AbstractPolyester manufacturing industries produce highly polluted effluents, containing organics, nutrients, trace metals, and 1,4-dioxane, requiring a high degree of treatment before being discharged into the water bodies. This study focused on removing complex pollutants from a diluted polyester industrial effluent (DPIE) via a cost-efficient anaerobic/aerobic combined system, with biogas recovery. The integrated pilot-scale system was composed of an up-flow anaerobic multi-staged reactor (UASR; V = 41 L) followed by an auto-aerated immobilized biomass (AIB; Vsponge = 9.54 L) unit and operated at a total organic loading rate (OLR) of 0.75 ± 0.16 g COD/L/d and pH of 7.14 ± 0.14 at 25 °C. The UASR achieved removal efficiencies of 17.82 ± 3.14% and 15.90 ± 3.08% for chemical oxygen demand (COD, total and soluble) and 15.83 ± 4.68% for total Kjeldahl nitrogen (TKN), with bio-CH4 yield of 263.24 ± 31.98 mL/g COD. Adding the AIB unit improved the overall CODtotal, CODsoluble, and TKN to 93.94 ± 2.39%, 94.84 ± 2.23%, and 75.81 ± 3.66%, respectively. The NH4-N removal efficiency was 85.66 ± 2.90% due to the oxic/nitrification condition on the sponge’s outer surface. The entire system also achieved 73.26 ± 2.68%, 77.48 ± 5.74%, and 81.26 ± 6.17% removals for Fe (3.93 ± 0.95 ppm), Zn (5.92 ± 2.32 ppm), and 1,4 dioxane (2.50 ± 0.61 ppm). Moreover, the UASR-AIB maintained removal efficiencies of 76.53 ± 8.47% and 77.51 ± 7.38% for total suspended solids (TSS: 335.95 ± 42.84 mg/L) and volatile suspended solids (VSS: 263.50 ± 36.94 mg/L). Regarding the DPIE toxicity level, the EC50 value increased from 12.9 to 39.4% after UASR/AIB application. The UASR’s microbial community at the genus level demonstrated that the synergistic cooperation of solubilization, hydrolysis, acidogenesis, acetogenesis, and methanogenesis was responsible for the degradation of DPIE components.
Experimental investigation on a lightweight, efficient, counter-rotating fan with and without boundary layer ingestion
Authors: Lengyel-Kampmann T. , Karboujian J. , Koc K. , Schnell R. , Winkelmann P. 
Published: March 2024

AbstractThe experimental investigations on the counter-rotating CRISPmulti fan with boundary layer ingestion are presented in this paper. The Counter Rotating Integrated Shrouded Propfan (CRISP) was designed, aerodynamically optimized and manufactured in lightweight material by the German Aerospace Center (DLR). The main task was to maximize the aerodynamic efficiency under restricted static, dynamic and acoustic properties of the blade designed with lightweight carbon-fiber material and to apply it as a demonstrator for the development of a new innovative blade manufacturing technology. The rotors were manufactured at the DLR Institute of Structures and Design and tested on the Multi-stage 2-shaft Compressor Test Facility (M2VP) at the DLR Institute of Propulsion Technology. The instrumentation enabled the measurement of the aerodynamic, static, dynamic and acoustic behavior of the fan. In general, the targets of the experimental investigation were to validate the optimization results, the numerical calculational methods and the acoustic tools. Additionally, inlet distortion measurements were carried out on the fan rig to investigate the effect of the boundary layer ingestion on a real counter-rotating propfan. A radially traversable disturbance body, designed to simulate the boundary layer of the aircraft fuselage on an aircraft architecture with embedded engines, enables a comprehensive measurement program to be carried out for both undisturbed and disturbed inflow.
The Crucial Roles of Diet, Microbiota, and Postbiotics in Colorectal Cancer
Authors: Kuru-Yaşar Rüya , Üstün-Aytekin Özlem 
Published: March 2024

Abstract
Purpose of Review
Colorectal cancer is the second deadliest cancer in the world, and its prevalence has been increasing alarmingly in recent years. After researchers discovered the existence of dysbiosis in colorectal cancer, they considered the use of probiotics in the treatment of colorectal cancer. However, for various reasons, including the low safety profile of probiotics in susceptible and immunocompromised patient5s, and the risk of developing antibiotic resistance, researchers have shifted their focus to non-living cells, their components, and metabolites. This review aims to comprehensively evaluate the literature on the effects of diet, microbiota, and postbiotics on colorectal cancer and the future of postbiotics.

Recent Findings
The link between diet, gut microbiota, and colorectal cancer has been established primarily as a relationship rather than a cause-effect relationship. The gut microbiota can convert gastrointestinal tract and dietary factors into either onco-metabolites or tumor suppressor metabolites. There is serious dysbiosis in the microbiota in colorectal cancer. Postbiotics appear to be promising agents in the prevention and treatment of colorectal cancer.

Summary
It has been shown that various postbiotics can selectively induce apoptosis in CRC, inhibit cell proliferation, growth, invasion, and migration, modulate the immune system, suppress carcinogenic signaling pathways, maintain intestinal epithelial integrity, and have a synergistic effect with chemotherapy drugs. However, it is also reported that some postbiotics are ineffective and may be risky in terms of safety profile in some patients. Many issues need to be researched about postbiotics. Large-scale, randomized, double-blind clinical studies are needed.
Incidence of invasive infections with Group B streptococcus in adults in Norway 1996–2019: a nationwide registry-based case–control study
Authors: Uggen Elise , Olaisen Camilla , Lyng Randi Valsø , Simonsen Gunnar Skov , Bævre-Jensen Roar Magne , Gran Frode Width , Åsvold Bjørn Olav , Nilsen Tom Ivar Lund , Damås Jan Kristian , Afset Jan Egil 
Published: March 2024

Abstract
Purpose
Group B streptococcus (GBS) colonizes the gastrointestinal and vaginal mucosa in healthy adults, but has also become an increasing cause of invasive infection. The aims of this study were to describe the incidence and factors associated with the occurrence of invasive GBS disease in adults in Norway.

Methods
We performed a nationwide retrospective case–control study of invasive GBS infections during 1996–2019, with two control groups; invasive Group A streptococcal disease (GAS) to control for changes in surveillance and diagnostics, and a second representing the general population.

Results
A total of 3710 GBS episodes were identified. The age-standardized incidence rate increased steadily from 1.10 (95% CI 0.80–1.50) in 1996 to 6.70 (95% CI 5.90–7.50) per 100,000 person-years in 2019. The incidence rate had an average annual increase of 6.44% (95% CI 5.12–7.78). Incidence rates of GAS varied considerably, and there was no evidence of a consistent change over the study period. GBS incidence was highest among adults > 60 years of age. Cardiovascular disease, cancer, and diabetes were the most common comorbid conditions. There was a shift in the distribution of capsular serotypes from three dominant types to more equal distribution among the six most common serotypes.

Conclusions
The incidence of invasive GBS disease in adults increased significantly from 1996 to 2019. The increasing age of the population with accompanying underlying comorbid conditions might contribute to the increasing burden of invasive GBS disease. Interestingly, type 1 diabetes was also associated with the occurrence of invasive GBS disease.
Tularemia on the rise in Switzerland? A one health approach is needed!
Authors: Buettcher Michael , Egli Adrian , Albini Sarah , Altpeter Ekkehardt , Labutin Anton , Guidi Valeria , Tonolla Mauro , Lienhard Reto , Opota Onya , Schmid Patrizia , Wuethrich Tsering , Schmidt Kristina M. ,   the TULAR-CH working group, Keller Peter , Bittel Pascal , Aebi Christoph , Schöbi Nina , Deak Csongor , Relly Christa , Bruhn Silke , Müller Dominik , Jost Geraldine , Schütz Sara 
Published: March 2024

AbstractIn the last 10 years, an increase in tularemia cases has been observed in both humans and animals in Switzerland. In these, infection with Francisella tularensis, the causative agent of the zoonotic disease tularemia, can occur through arthropod vectors or contact to infected animals or exposure to contaminated environmental sources. Currently, we are only able to postulate potential aetiologies: (i) behavioral changes of humans with more exposure to endemic habitats of infected arthropod vectors; (ii) an increased rate of tularemia infected ticks; (iii) increasing number and geographical regions of tick biotopes; (iv) increasing and/or more diverse reservoir populations; (v) increasing presence of bacteria in the environment; (vi) raised awareness and increased testing among physicians; (vii) improved laboratory techniques including molecular testing. To approach these questions, a one-health strategy is necessary. A functioning collaboration between public health, human medicine, and diagnostic and veterinary units for the control of tularemia must be established. Furthermore, the public should be included within citizen-supported-science-projects.
Oral findings in paediatric patients with severe heart, liver, and kidney failure prior to organ transplantation
Authors: Landén I. , Olander A. E. , Salmela E. , Jahnukainen T. , Ruokonen H. , Alapulli H. , Helenius-Hietala J. 
Published: March 2024

Abstract
Purpose
Organ transplantation is an effective treatment for children with severe heart, liver, and kidney diseases. These patient groups may have more oral and dental diseases than healthy controls. It is important to eliminate oral infection foci before transplantation and to maintain good oral health to avoid potential post-transplant complications. The aim of this study was to describe and compare oral health in Finnish paediatric heart, liver, and kidney transplant recipients prior to organ transplantation.

Methods
Eighty-six children who received a heart (n = 21), liver (n = 19), or kidney (n = 46) transplant in Finland during the years 2014–2018 were included in this study. The inclusion criterion was a pre-transplantation oral examination. Oral hygiene, enamel anomalies, and the number of decayed, missing, and filled teeth (dmft/DMFT) were analyzed retrospectively from medical and dental records and compared between the three patient groups.

Results
Children with liver (p = 0.043) or heart (p = 0.047) disease had higher combined primary and permanent dentition dmft/DMFT scores compared to children with kidney disease. A higher combined dmft/DMFT score was associated with poor oral hygiene (p = 0.005). No significant differences in oral hygiene between the patient groups were found. Furthermore, all patient groups had a high prevalence of developmental dental defects.

Conclusion
Children with liver or heart disease seem to have a higher combined dmft/DMFT score, indicating a higher prevalence of caries compared to children with kidney disease. Prevention of dental caries, along with promoting a good oral hygiene routine and regular check-ups, is suggested in these patient groups.