bluuebunny/crossref_metadata_2025_split huggingface dataset:
What else lies behind the credit rationing? Exploring the issue of employment
Authors: Vlassas Ioannis , Kallandranis Christos , Ballis Antonis , Glyptis Loukas , Thanh Lan Mai 
Published: April 2024

Purpose
This paper aims to review the literature extensively by analysing recent work and providing a guide for models, data sets and research findings.

Design/methodology/approach
This paper reviews the literature extensively by analysing recent work and providing a guide for models, data sets and research findings within the context of capital market imperfections. The authors further break down the literature into closer-in-nature categories for reader’s convenience and comprehension. Finally, the authors address gaps in the existing literature and propose government policies that can tone down the potential effect of credit rationing on employment.

Findings
This paper provides a map of the literature so as to help future researchers in the relevant literature and give a short insight of what has been explored so far.

Originality/value
This paper is original and is the result of a thorough review of an extensive literature.
The digital frontier of Islamic tax compliance: unveiling the influence of ICT as a moderator
Authors: Bhat Mohd Abass , Khan Shagufta Tariq , Al Balushi Yousuf Mohamed Zahran , Wedajo Abel Dula , Haseeb Mohammad 
Published: April 2024

Purpose
Based on the extended theory of planned behavior, this study aims to examine potential intentions-related factors that affect Islamic tax compliance moderated by information and communication technology (ICT) adoption.

Design/methodology/approach
A quantitative cross-sectional design was used to distribute questionnaire sets to 975 working Muslim Omanis by using convenience sampling method. PLS-SEM was mainly used to examine the data.

Findings
All the factors determine behavioral intention to pay Islamic tax (BIIT), which significantly predicts Islamic tax compliance behavior (ITCB). However, perceived control behavior negatively determines intention. ICT adoption moderates the link between BIIT and ITCB.

Practical implications
This study offers both practical and theoretical implications that can guide efforts to promote Islamic tax compliance and advance our understanding of tax behavior within the ETPB framework.

Originality/value
This study accounted for crucial factors determining intention than earlier ones using the ETPB. Considering technological advancements, the study also assessed the moderating role of ICT between BIIT and ITCB.
Ambidextrous knowledge accumulation, dynamic capability and manufacturing digital transformation in China
Authors: Qi Yong , Chen Qian , Yang Mengyuan , Sun Yilei 
Published: April 2024

Purpose
Existing studies have paid less attention to the impact of knowledge accumulation on digital transformation and its boundary conditions. Hence, this study aims to investigate the effects of ambidextrous knowledge accumulation on manufacturing digital transformation under the moderation of dynamic capability.

Design/methodology/approach
This study divides knowledge accumulation into exploratory and exploitative knowledge accumulation and divides dynamic capability into alliance management capability and new product development capability. To clarify the relationship among ambidextrous knowledge accumulation, dynamic capability and manufacturing digital transformation, the authors collect data from 421 Chinese listed manufacturing enterprises from 2016 to 2020 and perform analysis by multiple hierarchical regression method, heterogeneity test and robustness analysis.

Findings
The empirical results show that both exploratory and exploitative knowledge accumulation can significantly promote manufacturing digital transformation. Keeping ambidextrous knowledge accumulation in parallel is more conducive than keeping single-dimensional knowledge accumulation. Besides, dynamic capability positively moderates the relationship between ambidextrous knowledge accumulation and manufacturing digital transformation. Moreover, the heterogeneity test shows that the impact of ambidextrous knowledge accumulation and dynamic capabilities on manufacturing digital transformation varies widely across different industry segments or different regions.

Originality/value
First, this paper shifts attention to the role of ambidextrous knowledge accumulation in manufacturing digital transformation and expands the connotation and extension of knowledge accumulation. Second, this study reveals that dynamic capability is a vital driver of digital transformation, which corroborates the previous findings of dynamic capability as an important driver and contributes to enriching the knowledge management literature. Third, this paper provides a comprehensive micro measurement of ambidextrous knowledge accumulation and digital transformation based on the development characteristics of the digital economy era, which provides a theoretical basis for subsequent research.
Amazon Prime’s growth story faces hurdles in India
Authors: Saldanha Avil 
Published: April 2024

Research methodology
A secondary research method was used to collect data for this case. The authors have made use of newspaper articles and articles by experts published in the public domain.

Case overview/synopsis
This case discusses the dilemma faced by Amazon Prime Video in India regarding content. Amazon Prime Video attained success and rapid growth in India ever since its entry into the Indian over the top (OTT) market in 2016. However, the pursuit of attractive and bold content landed Amazon Prime Video in a legal tangle in India. Amazon Prime Video was accused of hurting the religious and political sentiments of Indians by broadcasting bold shows like Tandaav, Family Man, Mirzapur, Family Man 2, etc. Litigations against Amazon Prime Video were filed in the Indian courts by members of religious and political organizations. Protests and online campaigns on Twitter caught the attention of internet influencers in India. The key dilemma faced by the protagonist in this case is whether to continue streaming attractive content that may be controversial and may occasionally hurt the religious/political sentiments of some Indians or stream only safe content that may be deemed as boring by its young target audience.

Complexity academic level
Undergraduate and postgraduate students studying marketing management and international business courses in business management and commerce streams can use this case.
Association of cardiovascular disease prevalence with BMD and fracture in men with T2DM
Authors: Kong Xiao‐ke , Xie Rui , Zhang Deng , Chen Xiao‐jing , Wang Xiao‐feng , Lu Jie‐li , Zhao Hong‐yan , Liu Jian‐min , Sun Li‐hao , Tao Bei 
Published: April 2024

AbstractBackgroundPatients with type 2 diabetes mellitus (T2DM) are predisposed to cardiovascular disease (CVD). Bone mineral density (BMD) is linked to CVD, but most studies focused on women. Our analysis aims to explore the association of BMD and fracture with the prevalence of CVD in men with T2DM.MethodsIn this retrospective cross‐sectional study, 856 men with T2DM were enrolled. BMDs at the lumbar spine (L2‐4), femoral neck (FN), and total hip (TH) were measured by dual‐energy X‐ray absorptiometry (DXA). The CVD outcome was determined as the sum of the following conditions: congestive heart failure, coronary heart disease, angina pectoris, myocardial infarction, the requirement for coronary artery revascularization, and stroke. The relationship between BMDs and CVD was investigated by restricted cubic spline curves and logistic regression models.ResultsA total of 163 (19.0%) patients developed CVD. The restricted cubic spline curve revealed a linear and negative association between FN‐BMD, TH‐BMD, and CVD. After full adjustments for confounding covariates, the odds ratios were 1.34 (95% confidence interval [CI] [1.11–1.61], p < .05), 1.3 (95% CI [1.05–1.60], p < .05), and 1.26 (95% CI [1.02–1.55], p < .05) for each 1‐SD decrease in BMDs of L2‐4, FN and TH, respectively. T‐scores of < −1 for BMD of L2‐4 and FN were independently associated with CVD (p < .05). Subgroup analyses further supported our findings.ConclusionsThe prevalence of CVD was inversely correlated with BMD levels in men with T2DM, particularly at the FN. We hypothesized that monitoring FN‐BMD and early intervention would help reduce CVD risk in men with T2DM, especially those with hypertension.image
Exercise‐induced improvement of glycemic fluctuation and its relationship with fat and muscle distribution in type 2 diabetes
Authors: Liu Dan , Zhang Ying , Wu Qian , Han Rui , Cheng Di , Wu Liang , Guo Jingyi , Yu Xiangtian , Ge Wenli , Ni Jiacheng , Li Yaohui , Ma Tianshu , Fang Qichen , Wang Yufei , Zhao Yan , Zhao Yanan , Sun Biao , Li Huating , Jia Weiping 
Published: April 2024

AbstractAimsManagement of blood glucose fluctuation is essential for diabetes. Exercise is a key therapeutic strategy for diabetes patients, although little is known about determinants of glycemic response to exercise training. We aimed to investigate the effect of combined aerobic and resistance exercise training on blood glucose fluctuation in type 2 diabetes patients and explore the predictors of exercise‐induced glycemic response.Materials and MethodsFifty sedentary diabetes patients were randomly assigned to control or exercise group. Participants in the control group maintained sedentary lifestyle for 2 weeks, and those in the exercise group specifically performed combined exercise training for 1 week. All participants received dietary guidance based on a recommended diet chart. Glycemic fluctuation was measured by flash continuous glucose monitoring. Baseline fat and muscle distribution were accurately quantified through magnetic resonance imaging (MRI).ResultsCombined exercise training decreased SD of sensor glucose (SDSG, exercise‐pre vs exercise‐post, mean 1.35 vs 1.10 mmol/L, p = .006) and coefficient of variation (CV, mean 20.25 vs 17.20%, p = .027). No significant change was observed in the control group. Stepwise multiple linear regression showed that baseline MRI‐quantified fat and muscle distribution, including visceral fat area (β = −0.761, p = .001) and mid‐thigh muscle area (β = 0.450, p = .027), were significantly independent predictors of SDSG change in the exercise group, as well as CV change.ConclusionsCombined exercise training improved blood glucose fluctuation in diabetes patients. Baseline fat and muscle distribution were significant factors that influence glycemic response to exercise, providing new insights into personalized exercise intervention for diabetes.image
Does compulsion explain addiction?
Authors: Heinz Andreas , Gutwinski Stefan , Bahr Nadja Samia , Spanagel Rainer , Di Chiara Gaetano 
Published: April 2024

AbstractOne of the leading drug addiction theories states that habits and the underlying neural process of a ventral to dorsal striatal shift are the building blocks of compulsive drug‐seeking behaviour and that compulsion is the maladaptive persistence of responding despite adverse consequences. Here we discuss that compulsive behaviour as defined primarily from the perspective of animal experimentation falls short of the clinical phenomena and their neurobiological correlates. Thus for the human condition, the concept of compulsive habits should be critically addressed and potentially revised.
The expansion of the Australian tortoise beetle Trachymela sloanei (Chrysomelidae: Chrysomelinae, Chrysomelini, Paropsina) in Spain: Using human‐made shelters for an early detection strategy
Authors: Valera Francisco , Veiga Jesús , Moreno Eulalia , Bolonio Luis , Martínez Teresa 
Published: April 2024

Abstract
Invasive alien species are one main driver of biodiversity loss and can cause severe economic costs. Effective management of such species requires early detection of colonising individuals, but this is often hampered by biological or economic constraints.
Trachymela sloanei (Blackburn, 1896), an Australian Eucalyptus defoliator beetle, is an invasive alien species that has spread to the Americas, Asia and most recently Europe.
We analyse the expansion of T. sloanei in the Iberian Peninsula both at regional and local scales, study its phenology and relative abundance, and explore the use of nest boxes for early detection.
The species is spreading steadily, and the area potentially affected has increased dramatically in a few years. Both adults and larvae were observed between June and November, suggesting the occurrence of several overlapping generations. More than 300 individuals were found aggregated behind single nest boxes.
We conclude that the installation and monitoring of nest boxes or similar structures (e.g., cork boards) can facilitate early detection of this species.
Preventive allergen immunotherapy with inhalant allergens in children
Authors: Dwivedi Varsha , Kopanja Sonja , Schmidthaler Klara , Sieber Justyna , Bannert Christina , Szépfalusi Zsolt 
Published: April 2024

AbstractThe efficacy and safety of preventive allergen immunotherapy (pAIT) in children are currently under investigation. Here, we provide an overview of pAIT with respiratory allergens concerning the prevention of new sensitizations, allergic disease onset and progression as well as further immunomodulatory effects. Three databases were searched for clinical pAIT studies in children. Selected publications were reviewed for preventive outcomes according to prevention level (primary, secondary, and tertiary), allergen type, administration route, dose, and treatment duration. The primary prevention approach appears safe but showed no allergen‐specific effect on new sensitizations. Secondary prevention seems feasible and may induce regulatory T cell‐mediated immunotolerance. The number of studies at these prevention levels is limited. Tertiary prevention with grass and/or tree pollen‐based pAIT has shown efficacy in preventing disease progression from allergic rhinitis/conjunctivitis to asthma. Data on tertiary pAIT with house dust mites and other allergen types are inconclusive. Subcutaneous and sublingual routes appear similarly effective, but head‐to‐head comparative paediatric studies are scarce. Additionally, there are fewer placebo‐controlled studies. Nevertheless, immunomodulatory outcomes of pAIT are encouraging. Currently, limited but favourably suggestive evidence is available for preventing respiratory allergic diseases in children by pAIT. Primary and secondary prevention have potential and warrant further investigation through well‐designed studies.
Essential thrombocythaemia: A contemporary approach with new drugs on the horizon
Authors: Ferrer‐Marín Francisca , Hernández‐Boluda Juan Carlos , Alvarez‐Larrán Alberto 
Published: April 2024

SummaryEssential thrombocythaemia (ET) is a myeloproliferative neoplasm characterized by an increased risk of vascular complications and a tendency to progress to myelofibrosis and acute leukaemia. ET patients have traditionally been stratified into two thrombosis risk categories based on age older than 60 years and a history of thrombosis. More recently, the revised IPSET‐thrombosis scoring system, which accounts for the increased risk linked to the JAK2 mutation, has been incorporated into most expert recommendations. However, there is increasing evidence that the term ET encompasses different genomic entities, each with a distinct clinical course and prognosis. Moreover, the effectiveness and toxicity of cytoreductive and anti‐platelet treatments differ depending on the molecular genotype. While anti‐platelets and conventional cytoreductive agents, mainly hydroxycarbamide (hydroxyurea), anagrelide and pegylated interferon, remain the cornerstone of treatment, recent research has shed light on the effectiveness of novel therapies that may help improve outcomes. This comprehensive review focuses on the evolving landscape of treatment strategies in ET, with an emphasis on the role of molecular profiling in guiding therapeutic decisions. Besides evidence‐based management according to revised IPSET‐thrombosis stratification, we also provide specific observations for those patients with CALR‐, MPL‐mutated and triple‐negative ET, as well as cases with high‐risk mutations.
Transdermal oestradiol and exercise in androgen deprivation therapy (ESTRACISE): protocol
Authors: Jussila Ilkka , Ahtiainen Juha P. , Laakkonen Eija K. , Siltari Aino , Kaipia Antti , Jokela Tiina , Kärkkäinen Minta , Newton Rob , Raastad Truls , Huhtala Heini , Murtola Teemu J. , Seikkula Heikki 
Published: April 2024

ObjectiveTo report the protocol of a study evaluating the efficacy of transdermal oestradiol (E2) gel in reducing the adverse effects of androgen deprivation therapy (ADT), specifically on sexual function, and to assess the utility of E2 in combination with supervised exercise.Study Design and MethodsThe primary endpoint of this open‐label Phase IIA randomized controlled trial is the efficacy of transdermal E2 gel. Secondary endpoints include: (i) the occurrence of ADT‐induced adverse effects; (ii) the safety and tolerability of E2; (iii) the impact of E2 with or without exercise on physical, physiological, muscle, and systemic biomarkers; and (iv) quality of life. The trial will recruit high‐risk PCa patients (n = 310) undergoing external beam radiation therapy with adjuvant subcutaneous ADT. Participants will be stratified and randomized in a 1:1 ratio to either the E2 + ADT arm or the ADT‐only control arm. Additionally, a subset of patients (n = 120) will be randomized into a supervised exercise programme.ResultsThe primary outcome is assessed according to the efficacy of E2 in mitigating the deterioration of Expanded Prostate Cancer Index Composite sexual function domain scores. Secondary outcomes are assessed according to the occurrence of ADT‐induced adverse effects, safety and tolerability of E2, impact of E2 with or without exercise on physical performance, body composition, bone mineral density, muscle size, systematic biomarkers, and quality of life.ConclusionThe ESTRACISE study's innovative design can offer novel insights about the benefits of E2 gel, and the substudy can reinforce the benefits resistance training and deliver valuable new novel insights into the synergistic benefits of E2 gel and exercise, which are currently unknown.Trial RegistrationThe protocol has been registered in euclinicaltrials.eu (2023‐504704‐28‐00) and in clinicaltrials.gov (NCT06271551).
The insulin‐like growth factor binding protein–microfibrillar associated protein–sterol regulatory element binding protein axis regulates fibroblast–myofibroblast transition and cardiac fibrosis
Authors: Zhao Qianwen , Shao Tinghui , Huang Shan , Zhang Junjie , Zong Genjie , Zhuo Lili , Xu Yong , Hong Wenxuan 
Published: April 2024

Background and PurposeExcessive fibrogenesis is associated with adverse cardiac remodelling and heart failure. The myofibroblast, primarily derived from resident fibroblast, is the effector cell type in cardiac fibrosis. Megakaryocytic leukaemia 1 (MKL1) is considered the master regulator of fibroblast–myofibroblast transition (FMyT). The underlying transcriptional mechanism is not completely understood. Our goal was to identify novel transcriptional targets of MKL1 that might regulate FMyT and contribute to cardiac fibrosis.Experimental ApproachRNA sequencing (RNA‐seq) performed in primary cardiac fibroblasts identified insulin‐like growth factor binding protein 5 (IGFBP5) as one of the genes most significantly up‐regulated by constitutively active (CA) MKL1 over‐expression. IGFBP5 expression was detected in heart failure tissues using RT‐qPCR and western blots.Key ResultsOnce activated, IGFBP5 translocated to the nucleus to elicit a pro‐FMyT transcriptional programme. Consistently, IGFBP5 knockdown blocked FMyT in vitro and dampened cardiac fibrosis in mice. Of interest, IGFBP5 interacted with nuclear factor of activated T‐cell 4 (NFAT4) to stimulate the transcription of microfibril‐associated protein 5 (MFAP5). MFAP5 contributed to FMyT and cardiac fibrosis by enabling sterol response element binding protein 2 (SREBP2)‐dependent cholesterol synthesis.Conclusions and ImplicationsOur data unveil a previously unrecognized transcriptional cascade, initiated by IGFBP5, that promotes FMyT and cardiac fibrosis. Screening for small‐molecule compounds that target this axis could yield potential therapeutics against adverse cardiac remodelling.
Exploring individual parent‐to‐parent support interventions for parents caring for children with brain‐based developmental disabilities: A scoping review
Authors: Postma Amber , Ketelaar Marjolijn , van Nispen tot Sevenaer Justus , Downs Zahra , van Rappard Diane , Jongmans Marian , Zinkstok Janneke 
Published: April 2024

AbstractBackgroundBrain‐based developmental disabilities (BBDDs) comprise a large and heterogeneous group of disorders including autism, intellectual disability, cerebral palsy or genetic and neurodevelopmental disorders. Parents caring for a child with BBDD face multiple challenges that cause increased stress and high risk of mental health problems. Peer‐based support by fellow parents for a various range of patient groups has shown potential to provide emotional, psychological and practical support. Here, we aim to explore existing literature on individual peer‐to‐peer support (iP2PS) interventions for parents caring for children with BBDD with a view to (1) explore the impact of iP2PS interventions on parents and (2) identify challenges and facilitators of iP2PS.MethodAn extensive literature search (January 2023) was performed, and a thematic analysis was conducted to synthesize findings.ResultsFourteen relevant articles revealed three major themes regarding the impact of iP2PS on parents: (1) emotional and psychological well‐being, (2) quality of life and (3) practical issues. Four themes were identified describing challenges and facilitators of iP2PS: (1) benefits and burden of giving support, (2) matching parent‐pairs, (3) logistic challenges and solutions and (4) training and supervision of parents providing peer support.ConclusionsThis review revealed that iP2PS has a positive impact on the emotional and psychological well‐being of parents, as well as the overall quality of life for families caring for a child with a BBDD. Individual P2PS offers peer‐parents an opportunity to support others who are facing challenges similar to those they have experienced themselves. However, many questions still need to be addressed regarding benefits of different iP2PS styles, methods of tailoring support to individual needs and necessity of training and supervision for peer support providers. Future research should focus on defining these components and evaluating benefits to establish effective iP2PS that can be provided as standard care practice for parents.
Featured Cover
Authors: Davó Rubén , Fan Shengchi , Wang Feng , Wu Yiqun 
Published: April 2024

The cover image is based on the Original Article Long‐term survival and complications of Quad Zygoma Protocol with Anatomy‐Guided Approach in severely atrophic maxilla: A retrospective follow‐up analysis of up to 17 years by Rubén Davó MD et al., https://doi.org/10.1111/cid.13296.
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