bluuebunny/crossref_metadata_2025_split huggingface dataset:
Unusual parotid tumors
Authors: Parkin James L. , Stevens Michael H. 
Published: October 2006

AbstractThe patient presenting with a mass lesion of the parotid gland is frequently found to have a mixed tumor of salivary tissue origin. However, less common lesions occur in the anatomical region of the parotid gland. These pathological entities deserve consideration in the differential diagnosis.This report presents nine patients with unusual lesions occurring in the parotid region. These lesions include cervicofacial actinomycosis, branchial cleft cyst, parapharyngeal tumors, bony lesion of the mandible, non‐parotid origin malignant tumor, and metastatic malignant tumors. Each class of lesions demonstrated is also discussed.
Surgical management of airway obstructions during sleep
Authors: Simmons F. Blair , Guilleminault C. , Dement W. C. , Tilkian Ara G. , Hill M. 
Published: October 2006

AbstractAnatomical or physiological airway obstructions during sleep, of which the patient is unaware, cause daytime sleepiness at first, then signs of decreasing mental function, and eventually in some individuals, pulmonary and systemic hypertension. A few of these patients had been recognized before, the Pickwickian syndrome and in children with cardiac problems and large tonsils. The majority, however, present as sleep disorders. This paper describes our surgical experience with improving the airways of 19 children and adults with daytime somnolence.
Cranial neuropathies in sinus disease
Authors: Weisberger Edward C. , Dedo Herbert H. 
Published: October 2006

AbstractTo study the problem of cranial neuropathies in sinus disease the in‐patient experience at the University of California, San Francisco, and San Francisco General Hospitals was reviewed. The incidence of cranial nerve involvement in acute and chronic sinus inflammations was low (8 percent and 4 percent respectively). The incidence in neoplastic disease of the sinuses was considerably higher (32 percent). Cranial neuropathies occurred in inflammatory disease more frequently when associated with mucopyocele, mucormycosis, and orbital cellulitis. In both inflammatory and neoplastic disease, when cranial nerve deficits occurred, there was a high predelication for sphenoid sinus involvement. Several instructive case histories are included. The important anatomy of the cavernous sinus region and of the orbital apex as it pertains to this problem is discussed.
Glandular tumors of the external auditory canal
Authors: Pulec Jack L. 
Published: October 2006

AbstractThirty‐seven cases of ceruminous gland tumors of the external auditory‐canal are presented. These are rare tumors, each of which has different clinical characteristics. Six adenomas are reported which are benign and require only local excision for long‐term cure. Two muco‐epidermoid carcinomas, a type not previously reported, are presented. The muco‐epidermoid carcinoma tends to iecur locally and radical excision is necessary for control. The most common glandular tumor of the external auditory canal is the adenoid cystic carcinoma. Twenty‐four are reported. Pain is the hallmark of this tumor. The long clinical course ultimately results in death if the tumor is not radically removed at the earliest possible time. Radiation is ineffective. Treatment recommended is (1) wide excision of the external auditory canal, (2) extensive radical mastoidec‐tomy, and (3) total parotidectomy and mandibular condylectomy.Five cases of adenocarcinoma are presented. Four were dead from local invasion and distant metastasis within four years, and the fifth was lost to follow‐up.Careful histologie evaluation and classification of the type of tumor is necessary to predict the natural history and select the proper treatment. Local excision is curative for the benign adenoma. For the three types of carcinoma described, the surgeon must not hesitate to do the radical operation for the early lesion, because it is in the early stages that the opportunity to produce the cure exists.
Allergy in ménière's disease related fluctuating hearing loss preliminary findings in a double‐blind crossover clinical study
Authors: Endicott James N. , Stucker Fred J. 
Published: October 2006

AbstractSeveral clinical reports suggest allergy as a causative or associated factor in the etiology of Ménière's Disease or endolymphatic hydrops. The A.A.O.O. subcommittee reported in 1972 its criteria for a therapeutic improvement in Ménière's Disease. This important report allows for clinical studies to proceed in a scientific manner using the subcommittee's criteria to evaluate the results. In an ongoing study utilizing a double‐blind crossover technique, fourteen Ménière's patients have been evaluated for allergies utilizing the Rinlde and Lee techniques for inhalent and food allergies. Several cases directly relate their symptoms to specific food in‐gestion and were given challenge food tests.
Endolymphatic sac surgery
Authors: Edward Maddox H. 
Published: October 2006

AbstractThere is a disturbing variation in the reported success rate in Endolymphatic Sac Surgery in the literature. Relatively long‐term (24 months to 10 years) follow‐ups are given in a series of 66 patients in this paper. Results reveal only a 55% long‐term relief of veitigo in these patients. Only 30% of this series of cases had any improvement in cochlear function. There was a definite trend to Awards recurrence of vertigo in the longer follow‐up cases.It is concluded that Endolymphatic Sac Surgery still is important in the treatment of idiopathic endolymphatic hydrops, but is of questionable value early in the course of the disease. Total removal of the endolymphatic system remains the best single surgical approach in a large number of patients with Ménière's disease.
Mucocutaneous lymph node syndrome: A new clinical entity
Authors: Gross Charles W. , Chamberlain Morrow 
Published: October 2006

AbstractA six‐year‐old black male presented to the Otolaryngology service with fever, sore throat and an inflammatory mass in the left neck. Forty‐eight hours later he developed the full blown clinical picture of mucocutaneous lymph node syndrome (MLNS). This is a relatively new clinical entity, well known in Japan, but only recently described in the English literature.The following case report and discussion will serve to alert the otolaryngologist to this disease.
Morphologic analysis of tympanic membrane grafts
Authors: Lyons George D. , Dyer Robert F. , Ruby John R. 
Published: October 2006

AbstractMany materials are presently used for repair of tympanic membrane defects. Since the microscopic organization of these tissues may play a role with respect to the suitability of replacement of one with the other, a comparative electron microscopic study of temporalis fascia, fresh and preserved amniotic membrane was undertaken. An effort was made to determine the similarities and differences of these tissues and our clinical experience with their use is presented.
Presbycusis: What is it?
Authors: Lowell Seth H. , Paparella Michael M. 
Published: October 2006

AbstractThe history and current misusage of the term presbycusis is discussed and current knowledge of pathology associated with presbycusis and aging are reviewed. A study involving retrospective analysis of audio‐metric data and clinical information on three groups was performed. Results suggest that a group of individuals previously identified as “presby‐cusic” probably represent undiagnosed cases of familial or genetic related hearing loss. We urge as thorough an identification of correct diagnosis as possible, thus reserving the term “presbycusis” for those rare, solely age‐related cases of sensorineural loss.
Oncocytic lesions of the larynx
Authors: Oliveira Carlos A. , Roth James A. , Adams George L. 
Published: October 2006

AbstractTrue laryngeal adenomas are considered extremely rare and some doubt their existence. Laryngeal lesions having oncocytes as the predominant cell type have been described in the literature under a variety of different names: oncocytoma, oncocytic papillary cystadenoma, papillary cystade‐noma, oxyphilic granular cells adenoma, etc. The oncocytes originate from changes in normal acinic and ductal cells. The significance of these changes is controversial. Whether the oncocytic laryngeal lesions represent true neoplasms or are degenerative in nature remains to be determined.We present clinical and histopathological details of four cases of oncocytic lesions of the larynx and compare their histology with microscopic findings in 30 cases filed as laryngeal cysts at the Minneapolis V.A. and University of Minnesota Hospitals. While the controversy regarding the neoplastic versus degenerative etiology of these lesions could not be resolved from a histopathological standpoint, their clinical behavior is that of a benign neoplasm. We review the literature on the subject and suggest a course of treatment for these lesions.
Unrelated sensorineural hearing loss in patients with otosclerosis: A report of three cases
Authors: Linthicum Fred H. , Gail Nebly J. 
Published: October 2006

AbstractAlthough it is generally accepted that 20% or more of patients with clinically manifest otosclerosis have a concomitant sensorineural hearing loss,1 it is still debated whether otosclerosis is the cause of the neural loss.2Three cases are presented of other causes of sensorineural loss in oto‐sclerotic patients who underwent stapes surgery.One of these cases, the Mondini malformation, is discussed in detail.
Neurilemmoma of the auricle: A case report
Authors: Fodor Raymond I. , Pastore Peter N. , Frable Mary Ann 
Published: October 2006

AbstractA report of a case of a solitary benign neurilemmoma of the auricle is presented. It is believed to be the first such documented case. Its nature, histology, and differential diagnosis is reviewed. It is suggested that “neu‐rogenic tumors” be added on to the current classification of auricular masses.
Melanoma and the differential diagnosis of oral pigmented lesions.
Authors: Powell Jeffrey P. , Cummings Charles W. 
Published: October 2006

AbstractThere are many pathologic processes that occur in the mouth which have various intraoral manifestations. The differential diagnosis of pigmented lesions of the oral cavity takes on a high degree of significance because therapy may span such a wide range from no treatment at all to massive radical resection for melanoma. A thorough understanding of pigmented lesions of the oral cavity would assist the clinician in establishing a diagnosis and subsequent treatment plan. A comprehensive review of the literature and a discussion of oral pigmented lesions including infiltrative malignant melanoma is presented.
Etiologic factors in hypocalcemia secondary to operations for carcinoma of the pharynx and larynx.
Authors: Isaacson Steven R. , Snow James B. 
Published: October 2006

AbstractHypocalcemia, although a relatively uncommon sequela of operations for carcinoma of the larynx and pharynx, often presents as an acute medical emergency. In its chronic form, hypocalcemia may be a difficult disorder to control.Understanding the etiologic basis of hypocalcemia secondary to operations for carcinoma of the head and neck requires knowledge of the pathophysiology of the preoperative and postoperative factors affecting calcium homeostasis. These factors include thyroidectomy, hypoparathyroidism, hypomagnesemia, anticonvulsant therapy, estrogen replacement therapy, oral contraceptives, blood transfusions, hyperventilation alkalosis, hypoalbuminemia, corticosteroid therapy, depression, emotional stress and diet.Often the onset of symptoms and signs of hypocalcemia occurs within 24 to 48 hours after the operation. The symptoms may include mental depression, headache, tingling of the hands and perioral region and abdominal pain. Unrecognized chronic hypocalcemia may lead to the development of cataracts, convulsions and psychosis.Management requires an appreciation of the etiologic factors as well as the complications of vitamin D therapy.
The otolaryngologic manifestations of multiple myeloma.
Authors: Creston James E. 
Published: October 2006

AbstractThe purpose of this paper is to present the precursors and complications of multiple myeloma as manifested in Otolaryngology. The modern Otolaryngologist is well aware that systemic disease may manifest itself in our specialty. Multiple myeloma is a distinctive form of plasma cell dyscrasia which often manifests itself in Otolaryngology. For example, patients may present with epistaxis, hoarseness, asymmetry of the face, swelling of the palate, nasal obstruction and a multiplicity of other symptoms. Therefore, the practicing Otolaryngologist must maintain a high index of suspicion that a seemingly simple sign or symptom may represent one small facet of a generalized condition. The paper emphasizes that in many instances a slight extension of our history taking may provide us with information leading to the diagnosis of this systemic disease.Cases seen by the author are reviewed and the relevant clinical features are presented.
Bilateral sudden deafness following combined insecticide poisoning.
Authors: Harell Moshe , Shea John J. , Emmett John R. 
Published: October 2006

AbstractA case of combined poisoning due to exposure to an aerosol containing both malathion and methoxychlor (sold under the trade name OrthoTM Orchard Spray in the United States) is presented. The following unusual features occurred in the course and outcome of the poisoning: slow onset of symptoms and signs, bilateral profound and permanent sensorineural hearing loss, and residual peripheral neuropathies in the extremities. The possible potentiation of the usually low toxicity of malathion is suggested and discussed.
Facial palsy: Interpretation of neurologic findings.
Authors: May Mark , Hardin William B. 
Published: October 2006

AbstractA review of the otoneurologic findings in 500 patients with facial paralysis revealed their importance for diagnosis, prognosis, and understanding the pathophysiology of Bell's palsy.Diagnosis. The presence of simultaneous bilateral palsy, facial paralysis associated with lateral rectus palsy, slowly progressive facial weakness with or without hyperkinesis, and facial paralysis that showed no recovery after six months excluded Bell's palsy from the diagnosis. Ipsilateral recurrent palsies were another indication to suspect an underlying cause, since a tumor of the facial nerve caused the paralysis in 30% of the patients with this finding. Signs such as intact forehead movement, alterations in facial sensation, and corneal hypesthesia — although often associated with lesions in the cerebral cortex, cerebellopontine angle, or internal auditory canal — were also found in patients with Bell's palsy.Prognosis. A spontaneous complete recovery following Bell's palsy occurs in about 70% of the patients; but in the presence of a dry eye or dysacousis, the prognosis for a complete recovery drops to 10 and 25%, respectively.Pathophysiology. It is proposed that the wide range of neurologic findings associated with Bell's palsy is due to a viral polyneuropathy. This is a disorder that primarily involves sensory nerves, and the facial motor deficit results from involvement of the sensory fibers carried with the facial nerve within the fallopian canal.
Surgical approach to tumors of the nasal cavity
Authors: Pope Thad H. 
Published: October 2006

AbstractIn the past there has been a general reluctance among rhinologists to remove the entire lateral nasal wall for fear of causing drastic disturbances of nasal physiology. It has been our observation that the physiological disturbances are fairly minimal if the patient, following surgery, uses nasal saline irrigations daily. Sometimes a nasal siphon or water pik is required to prevent crusting. It has also been noted that when the septum is removed, a chronic antritis on the contralateral side will usually occur. It has been our practice to do an antrostomy on the uninvolved side when the septum has been removed for any reason.Ophthalmologists have shown some reticence to having the entire bony support of the medial wall of the orbit and half the floor removed. This does necessitate transecting the lacrimal duct at its neck. We have, however, seen no trouble with epiphora following this provided the sac was allowed to drain into the open nasal cavity. The trochlea is by necessity deprived of its support; however, the periostium seems to provide adequate support here and we have noticed no troublesome permanent problems with function of this muscle. The periorbita, which has been robbed of its osseous support, quickly epithelializes with nasal mucosa and becomes a part of the nasal cavity. Requirements for intranasal douching with saline have varied; however, we have had no problems with bothersome crusting following b.i.d. nasal irrigations. In cases where a small portion of the inferior turbinate could be preserved, there was always extreme hypertrophy of this remnant which usually brings the nasal physiology back to a nearly normal state which seldom requires any special care whatever.This paper presents primarily a method of approaching tumors of the sinonasal area, especially when there is difficulty in determining whether the lesion arises from the septum or lateral wall of the nose.
Anatomical consequences of CO2 laser surgery of the guinea pig ear
Authors: Lyons George D. , Webster Douglas B. , Mouney Daniel F. , Lousteau Ray J. 
Published: October 2006

AbstractA modified American Optical (Model 100) CO2 laser was used to produce lesions in the tympanic membranes, ossicles, and cochlear capsules of guinea pigs. Even with the lowest available intensities and durations (0.4 watts, 50 msec), there was damage to the inner ear. Although laser surgery of the ear can avoid mechanical trauma and bleeding as well as increase accuracy, the use of commercial lasers in ear surgery should be avoided until a proven unit is avaliable.
Drug therapy in otomycosis: Anin vitrostudy
Authors: Lawrence Thomas L. , Ayers Leona W. , Saunders William H. 
Published: October 2006

AbstractOtomycosis represents a small percentage of clinical external otitis. This well documented entity is often a stubborn clinical problem and, in contrast to bacterial external otitis, there is no otic preparation with specific antifungal activity. In response to this lack of otic preparations, we have surveyed in vitro a variety of available preparations to determine the general spectrum of activity against appropriate bacterial and fungal species. An agar‐disc diffusion system was used testing the drugs against (1.) bacteria common in external otitis, and (2.) a variety of yeast and filamentous fungi.Aqueous Merthiolate and Cresylate demonstrated good non‐specific antimicrobial activity, while nystatin and clotrimazole demonstrated specific antifungal activity. Otic preparations can now be used which have demonstrated in vitro effectiveness and give an alternate means of therapy to the now empirically selected otic preparation used for otomycosis.
The etiology of laryngeal papillomatosis
Authors: Quick Cedric A. , Faras Anthony , Krzysek Richard 
Published: October 2006

AbstractSophisticated virological techniques are described for isolating whole virus, free viral DNA, or integrated viral DNA. Based upon preliminary results, it is suggested that the virus responsible for laryngeal papillomatosis is not the same as the virus responsible for cutaneous papillomatosis lesions and, for the most part, it exists in the integrated DNA form.
The frey syndrome: A review and double blind evaluation of the topical use of a new anticholinergic agent
Authors: Hays Leonard L. 
Published: October 2006

AbstractThe symptom complex of localized facial gustatory sweating and flushing during mastication (The Frey syndrome) is a common sequela of parotidectomy with facial nerve dissection.A thorough review of the literature concerning the Frey syndrome is reported. The procedure of tympanic neurectomy has received special emphasis with a review of 73 cases of tympanic neurectomy. The treatment modalities available, if tympanic neurectomy fails, are discussed. Important guidelines for the safe use of topical therapy to control gustatory sweating are presented as an alternative to surgical therapy.The author studied 129 post parotidectomy patients in whom 60% noted symptomatic gustatory sweating, and approximately one‐fourth of these symptomatic patients requested topical anticholinergic therapy, with one patient electing tympanic neurectomy.The only form of medical treatment presently available utilizes the topical application of scopolamine, a drug having potentially significant central nervous system side effects if systemically absorbed. In an effort to find an effective drug for topical application with a more favorable therapeutic index than scopolamine, glycopyrrolate was investigated. Glycopyrrolate was compared in varying concentrations to topical scopolamine in a personally conducted double blind clinical trial involving 16 patients.Initial results of this investigation suggest that topical glycopyrrolate in concentrations of 0.5% and 1.0% provide complete effective control of gustatory sweating for at least several days duration after a single application. There have been no significant side effects with the use of topical glycopyrrolate to date. Commercial topical antiperspirants were also investigated and found to be of limited benefit.
Altered bacterial flora and clinical course with intraoral cancer
Authors: Rice Dale H. , Weimert Thomas A. 
Published: October 2006

AbstractNineteen consecutive patients with intraoral cancer were cultured and tested for cell‐mediated immunity. They were then treated and followed for three years. The recurrence rate for those patients with normal flora was similar to that reported for dinitrochlorobenzene (DNCB) reactors; and the recurrence rate for those patients with abnormal microorganisms was similar to that reported for DNCB non‐reactors.
Symposium: Value and cost analysis of recent ear tests. The value and cost analysis of the eng as of 1978
Authors: Rubin Wallace 
Published: October 2006

AbstractThe use of ENG in office practice and its use as a helpful, time‐saving procedure is discussed. The following practical clinical questions are answered: 1. Is the vestibular mechanism normal or abnormal? 2. Is the vestibular pathology peripheral or central? 3. Is the peripheral disease right or left sided? Cost analysis of ENG in office practice is presented.
Symposium: Value and cost analysis of recent ear tests. Air caloric testing in otitis media (preliminary studies)
Authors: Paparella Michael M. , Rybak Leonard , Meyerhoff William L. 
Published: October 2006

AbstractOn certain occasions it becomes inportant to evaluate vestibular function in a patient with otitis media. The potential application of the air caloric test in evaluating such patients was examined. Patients with unilateral otitis media before and after surgery were studied to answer certain clinical questions. More questions were raised than answers provided. The preliminary conclusions from this study are:Patients with tympanostomy tubes or small perforation of one ear may show a caloric response in the perforated ear equal to that of the intact ear.Patients with a large tympanic membrane perforation on one side may show hyperactive caloric responses on the perforated side.Patients with a moist ear may show inverted horizontal nystagmus to warm air caloric testing. This applies to patients with a large perforation or mastoidectomy cavity.Patients with a dry open mastoid or fenestration cavity are likely to show a hyperactive caloric response on the side of previous surgery, accompanied by vegetative symptoms. This size of the cavity appears to be less important than the presence of the cavity per se.Patients may be safely tested in the early postoperative period.