bluuebunny/crossref_metadata_2025_split huggingface dataset:
ChemInform Abstract: Low‐Temperature Synthesis of β‐FeSi2 Powder Using a Sodium Melt.
Authors: Yamada Takahiro , Yamane Hisanori 
Published: January 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Metallocanes of Group 14 Elements. Part 2. Derivatives of Tin
Authors: Selina A. A. , Karlov S. S. , Lermontova E. Kh. , Zaitseva G. S. 
Published: January 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Stereochemistry, Syntheses and Biological Activity of Lupine Alkaloids — From Studies on the Leguminous Plants Growing Mainly in Japan
Authors: Ohmiya Shigeru 
Published: January 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Structural and Functional Studies on Proteins as Potential Drug Discovery Targets
Authors: Tanaka Nobutada 
Published: January 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Hypervalent Silicon‐Containing Organosilicon Derivatives of Nitrogen Heterocycles
Authors: Voronkov M. G. , Trofimova O. M. , Bolgova Yu. I. , Chernov N. F. 
Published: January 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Discotic Liquid Crystals: A New Generation of Organic Semiconductors
Authors: Sergeyev Sergey , Pisula Wojciech , Geerts Yves Henri 
Published: January 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Chain‐Link Hydrogen‐Bonded Capsules
Authors: Bosch Eric 
Published: January 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Selective Biomimetic Epoxidations
Authors: Breslow Ronald 
Published: January 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: From Divergent to Focused Approaches to Amino Alcohols and Amino Diols: Applications to the Synthesis of Natural and Unnatural Products
Authors: Restorp P. , Torsell S. , Somfai P. 
Published: January 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Combinatorial Chemistry: From Split‐Mix to Discrete
Authors: Furka Arpad 
Published: January 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Organotin Chemistry
Authors: Wrackmeyer Bernd 
Published: January 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Julius Adolph Stöckhardt – seine Spuren in Chemnitz
Authors: Marx Günter , Molch Dieter , Kerber Klaus‐Peter , Lang Heinrich 
Published: January 2008

AbstractJulius Adolph Stöckhardt ‐ ein bemerkenswert befähigter Lehrer für die Studenten, ein technischer Chemiker für die aufwachsende Industrie, ein Umwelt‐ und Landwirtschaftschemiker, ein forschender Partner im Sinne Justus von Liebig.Die Stöckhardt‐Aufgaben können bei Bedarf bei den Autoren angefordert werden.
So funktioniert Forschung
Authors: Näther Christian , Bensch Wolfgang 
Published: January 2008

AbstractSeit Jahren ist die Chemie in einem fortwährenden Wandel begriffen. Gehörten vor einigen Jahren noch Dünger, Pigmente oder einfache Grundchemikalien zu den wichtigsten anorganischen Produkten der chemischen Industrie, so dominieren seit einiger Zeit High‐Tech‐Werkstoffe, die vor allem in der Zukunft von enormer Bedeutung sein werden [1]. Von der Entwicklung neuer Materialien und Werkstoffe mit spezifischen physikalischen Eigenschaften für technologisch relevante Anwendungen wird daher die Zukunft, insbesondere unserer westlichen Welt mit abhängen. Nun erfordert die Darstellung und Charakterisierung derartiger Materialien ganz spezielle synthetische und analytische Methoden. Gehörten früher Reagenzglas und Erlenmeyerkolben zum Rüstzeug des Chemikers, so hat sich das in den letzten Jahren insbesondere im Bereich der Anorganischen Chemie grundlegend geändert. Moderne Chemie, unabhängig davon, ob sie an einer Universität oder in der Industrie durchgeführt wird, kommt ohne leistungsfähige synthetische und instrumentelle Methoden nicht aus.
Thermochromie – ein altes und neues faszinierendes Phänomen
Authors: Leppin Ines , Voß Carsten , Freienberg Julia , Evers Rainer , Flint Alfred 
Published: January 2008

AbstractDer Begriff „Thermochromie”︁T leitet sich aus den griechischen Bezeichnungen für Wärme („thermos”︁) und Farbe („chroma”︁) ab. Bezeichnet wird damit das Auftreten reversibler Farbänderungen von Stoffen in Abhängigkeit von der Temperatur. Entsprechende Erscheinungen sind im Bereich der Anorganischen Chemie schon seit langem bekannt. Ein klassisches Beispiel ist der rote Rubin, der sich beim Erhitzen grün färbt und beim Abkühlen wieder rot wird. Aber auch wenn man gerade keinen Rubin zur Hand hat, lassen sich thermochrome Effekte z.B. beim Zinkoxid (in der Kälte weiß, in der Hitze gelb) oder, wie vor einiger Zeit beschrieben, beim Kupfer(I)oxid (in der Kälte rot, in der Hitze schwarz) beobachten [1].Aber auch im Bereich der Organischen Chemie hat es bereits gegen Ende des 19. Jahrhunderts erste Beobachtungen und Untersuchungen zu thermochromen Erscheinungen im Zusammenhang mit der Entdeckung von Flüssigkristallen durch Reinitzer und Lehmann sowie deren maßgebliche Klassifikation und Beschreibung durch Friedel gegeben (nach [2]). Interessanterweise waren alle drei keine Chemiker, sondern Lehmann und Friedel Physiker und Reinitzer Botaniker. Abgesehen von dem akademischen Interesse an diesen Stoffen dauerte es allerdings bis in die 50er und 60er Jahre des vergangenen Jahrhunderts, bis eine intensive Forschung auf dem Gebiet der Flüssigkristalle im Hinblick auf eine Anwendung deren thermochromer, vor allem aber ihrer elektrooptischen Eigenschaften einsetzte. Aus unserer heutigen Gesellschaft sind z.B. LCD‐Displays oder seit neuestem LCD‐Fernseher kaum noch wegzudenken.
Cyberinfrastructure für die Organische Chemie
Authors: Fels Gregor 
Published: January 2008

AbstractQualität der Lehre und Internationalisierung gehören zum Stammvokabular der Akkreditierungskommissionen für die neuen Bachelor‐ und Masterstudiengänge. Mit den neuen internetbasierten online‐Lehrbüchern der Chemie, in Kombination mit einem „Webcompanion”︁, in dem zusätzlich zum Lehrbuch multimediale Lernhilfen und Trainingsmöglichkeiten gegeben sind, lassen sich Lehrveranstaltungen effektiver gestalten und didaktisch verbessern und ggf. die englische Fachterminologie bereits in einem frühen Stadium des Studiums einbringen.
Molecular characterization and expression of a novel kinesin which localizes with the kinetoplast in the human pathogen, Leishmania donovani
Authors: Gerald Noel J. , Coppens Isabelle , Dwyer Dennis M. 
Published: January 2008

AbstractUsing a variety of molecular and cell biological approaches, we identified, characterized and expressed a novel kinesin, LdK39B in the protozoan pathogen Leishmania donovani. Results of RT‐PCR revealed two distinct LdK39B products with different splice leader mini‐exon sites, indicative of two potentially mature mRNA transcripts. Analyses indicated that LdK39B had a calculated molecular mass of >261, 327 Da and contained multiple amino acid repeat units. Several GFP‐LdK39B fusion constructs were generated and used for episomal‐expression in these parasites. Results of confocal and immunoelectron microscopy indicated that the GFP‐LdK39B‐fusion proteins localized to a region adjacent to the flagellar pocket and the kinetoplast i.e. the mitochondrial‐DNA containing organelle that is physically tethered to the flagellar basal bodies. Sub‐cellular fractionation results showed that GFP‐LdK39B proteins were insoluble in nature and remained tightly associated with purified flagella/kinetoplasts following their extraction with detergent and high salts. Our cumulative results suggest that the LdK39B may play a scaffold‐like role in facilitating and maintaining the unique spatial/structural association between the flagellum‐basal body‐kinetoplast complex in these parasites. Cell Motil. Cytoskeleton 2008. Published 2008 Wiley‐Liss, Inc.
G‐Quadruplexes: Targets in Anticancer Drug Design
Authors: Ou Tian‐miao , Lu Yu‐jing , Tan Jia‐heng , Huang Zhi‐shu , Wong Kwok‐Yin , Gu Lian‐quan 
Published: January 2008

AbstractG‐quadruplexes are special secondary structures adopted in some guanine‐rich DNA sequences. As guanine‐rich sequences are present in important regions of the eukaryotic genome, such as telomeres and the regulatory regions of many genes, such structures may play important roles in the regulation of biological events in the body. G‐quadruplexes have become valid targets for new anticancer drugs in the past few decades. Many leading compounds that target these structures have been reported, and a few of them have entered preclinical or clinical trials. Nonetheless, the selectivity of this kind of antitumor compound has yet to be improved in order to suppress the side effects caused by nonselective binding. As drug design targets, the topology and structural characteristics of quadruplexes, their possible biological roles, and the modes and sites of small‐ligand binding to these structures should be understood clearly. Herein we provide a summary of published research that has set out to address the above problem to provide useful information on the design of small ligands that target G‐quadruplexes. This review also covers research methodologies that have been developed to study the binding of ligands to G‐quadruplexes.
Synthesis and Biological Activity of a Novel Inhibitor of Dihydroceramide Desaturase
Authors: Munoz‐Olaya Jose M. , Matabosch Xavier , Bedia Carmen , Egido‐Gabás Meritxell , Casas Josefina , Llebaria Amadeu , Delgado Antonio , Fabriàs Gemma 
Published: January 2008

AbstractA novel mechanism‐based dihydroceramide desaturase inhibitor (XM462) in which the substrate C5 methylene group is replaced by a sulfur atom is reported. Dihydroceramide desaturase inhibition occurred both in vitro and in cultured cells with IC50 values of 8.2 and 0.78 μM, respectively, at a substrate concentration of 10 μM. In vitro experiments showed that XM462 produced a mixed‐type inhibition (Ki=2 μM, α=0.83). LC‐MS analyses showed that accumulation of endogenous dihydroceramides occurred in cells upon treatment with XM462 in serum‐free medium, whereas ceramides built up in controls. In addition, XM462 was found to be metabolised to its 1‐glucosyl and 1‐phosphocholine derivatives, and to the products of N‐deacylation and reacylation with palmitoyl and stearoyl groups. In Jurkat A3 cells cultured in serum‐free medium, viability, as the percentage of trypan blue unstained cells in total cells, was reduced upon XM462 treatment (5 μM, 24 h), but not in controls. The interest of this compound is discussed.
(1+1) Resonance‐Enhanced Multiphoton Ionization and Photodissociation Study of CS2 via the 1B2 State
Authors: Hu Zhengfa , Lee Wei‐Bin , Zhang Xiao‐Peng , Wei Pei‐Ying , Lin King‐Chuen 
Published: January 2008

Abstract(1+1) resonance‐enhanced multiphoton ionization (REMPI) spectra of CS2 and molecular dissociation dynamics are investigated using a time‐of‐flight mass spectrometer equipped with velocity imaging detection. The REMPI spectra via a linear‐bent ${{}^1\Sigma _g^ + }$→1B2(${{}^1\Sigma _u^ + }$) transition are acquired in the wavelength range of 208–217 nm. Each ro‐vibrational band profile of the 1B2(${{}^1\Sigma _u^ + }$) state is deconvoluted to yield the corresponding predissociative lifetime from 0.3 to 3 ps. Upon excitation at 210.25 and 212.54 nm, the resulting images of S+ and CS+ fragments are analyzed to give individual translational energy distributions, which are resolved into two components corresponding to the CS+S(3P) and CS+S(1D) channels. The product branching ratios of S(3P)/S(1D) are evaluated to be 5.7±1.0 and 9.6±2.5 at 210.25 and 212.54 nm, respectively. Despite the difficulty avoiding the effect of multiphoton absorption, the molecular dissociation channel is verified to prevail over the dissociative ionization channel of CS2. The anisotropy parameters for the triplet and singlet channels are determined to be ∼0.8 and 1.1–1.3, respectively, suggesting that the predissociative state should have a bent configuration with a short lifetime.
A structural index to affect the operation life of steam turbine generators
Authors: Lin Chi‐Hshiung 
Published: January 2008

AbstractSince there is a largest occurrence probability among power line faults, the single‐phase‐to‐ground fault (1P‐G fault) plays a non‐negligible role on fatigue life of a turbine generator unit. It is found in this paper that the system frequency disturbance is the principal one to arouse torsional vibrations on turbine mechanism under a 1P‐G fault, which is different from the unidirectional one for a three‐phase‐to‐ground fault (3P‐G fault). By analyzing the turbine‐generator‐exciter‐blade model using the electromechanical analogy, it is further found that the structural index ofKGEN‐TURB/HGENratio governs the response sensitivity to such a disturbance. That means the larger the ratio is, the severer the torsional vibrations induced will be. According to this result, it can be deduced that the coming generation of turbine generator units would get more sensitive to the 3P‐G fault because the tendency is toward reducing the inertia of generators. Copyright © 2008 John Wiley & Sons, Ltd.
Hierarchical Structures in Tin(II) Oxalates
Authors: Ramaswamy Padmini , Datta Ayan , Natarajan Srinivasan 
Published: January 2008

AbstractSix new SnII oxalates exhibiting a hierarchy of structures have been prepared employing hydrothermal methods. The compounds I [C10N2H10][Sn(C2O4)2], II [C10N2H10][Sn2(C2O4)3], and III [C8N4H26][Sn(C2O4)2]2·2H2O possess zero‐dimensional molecular structures; IV [C10N2H8]2[Sn(C2O4)]2 and V [C12N2H8][SnC2O4] have one‐dimensional chain structures; and compound VI [C5N2H14]2[Sn4(C2O4)6]·7H2O has a two‐dimensional layer structure. The SnII ions have 4‐ and 6‐coordination with square‐pyramidal or pentagonal‐bipyramidal geometry, in which the lone pair of electrons also occupies one of the vertices. Weak intermolecular forces such as hydrogen‐bond interactions, π···π interactions, and lone‐pair–π interactions have been observed and appear to lendstructural stability. Theoretical studies indicate that the π···π interaction energy between the bound 1,10‐phenanthroline molecules is of the order of 5–6 kcal mol–1 in V. Natural bond orbital (NBO) analysis on two model compounds, II and IV, indicates reasonable lone‐pair–π interactions. The close structural relationship between all the compounds indicates that a building‐up process from the zero‐dimensional monomer can be considered. The present structures provide opportunities for evaluating the structure‐directing role of the lone pair of electrons of SnII.(© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2008)
Tunable Synthesis of Various Hierarchical Structures of In(OH)3 and In2O3 Assembled by Nanocubes
Authors: Chen Li‐Yong , Zhang Yan‐Ge , Wang Wei‐Zhi , Zhang Zu‐De 
Published: January 2008

AbstractWe show a simple way to synthesize morphology‐controllable In(OH)3 nanostructures by utilizing an amine‐assisted hydrolysis of In3+ cations under various reaction temperatures. By annealing as‐prepared In(OH)3 precursors at 400 °C in air, we obtained In2O3 nanocrystals that inherited the morphologies of their precursors while still slightly distorted due to the dehydration process of In(OH)3. This dehydration process that transforms In(OH)3 into In2O3 was studied by thermogravimetry and differential thermal analysis. X‐ray powder diffraction, field emission scanning electron microscopy, transmission electron microscopy, and photoluminescence spectra were used to characterize the as‐obtained products. Fourier transform infrared absorption spectra were recorded to investigate the effect of ethylenediamine in In(OH)3. It was found that the amines play ternary roles, which include being the alkaline media, the coordinating agent, and the surface‐anchored organic molecules.(© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2008)
Fluorous Substituent‐Based Enantiomer and Diastereomer Separation: Orthogonal Use of HPLC Columns for the Synthesis of Nonproteinogenic Polyfluoro Amino Acids and Peptides
Authors: Tonoi Takayuki , Nishikawa Aya , Yajima Tomoko , Nagano Hajime , Mikami Koichi 
Published: January 2008

AbstractA variety of fluorine‐containing amino acid and dipeptide precursors bearing different lengths of perfluoroalkyl chains were separated into their enantiomers and diastereomers, respectively, by the orthogonal use of fluorous and chiral HPLC columns. These results show the applicability of fluorous racemic mixture synthesis for various “fluorinated” chiral products without introducing conventional cleavable fluorous tags. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2008)
Use of mechanistic data in IARC evaluations
Authors: Cogliano Vincent James , Baan Robert A. , Straif Kurt , Grosse Yann , Secretan Béatrice , El Ghissassi Fatiha 
Published: January 2008

AbstractConsideration of mechanistic data has the potential to improve the analysis of both epidemiologic studies and cancer bioassays. IARC has a classification system in which mechanistic data can play a pivotal role. Since 1991, IARC has allowed an agent to be classified as carcinogenic to humans (Group 1) when there is less than sufficient evidence in humans but there is sufficient evidence in experimental animals and “strong evidence in exposed humans that the agent acts through a relevant mechanism of carcinogenicity.” Mechanistic evidence can also substitute for conventional cancer bioassays when there is less than sufficient evidence in experimental animals, just as mechanistic evidence can substitute for conventional epidemiologic studies when there is less than sufficient evidence in humans. The IARC Monographs have used mechanistic data to raise or lower a classification that would be otherwise based on epidemiologic studies and cancer bioassays only. Recently, the IARC Monographs have evaluated several agents where mechanistic data were pivotal to the overall evaluation: benzo[a]pyrene, carbon black and other poorly soluble particles, ingested nitrates and nitrites, and microcystin‐LR. In evaluating mechanistic data, it is important to consider alternative mechanistic hypotheses, because an agent may induce tumors through multiple mechanisms. Environ. Mol. Mutagen., 2008. © 2008 Wiley‐Liss, Inc.
DNA damage induced by industrial solid waste leachates in Drosophila melanogaster: A mechanistic approach
Authors: Siddique Hifzur R. , Sharma Anurag , Gupta Subash C. , Murthy Ramesh C. , Dhawan Alok , Saxena Daya K. , Chowdhuri Debapratim K. 
Published: January 2008

AbstractGenomic stability requires that error‐free genetic information be transmitted from generation to generation, a process that is dependent upon efficient DNA repair. Industrial leachates which contain mixtures of diverse chemicals are a major environmental concern. The interaction between these chemicals may have synergistic, antagonistic, or simply additive effects on biological systems. In the present study, the Comet assay was used to measure the DNA damage produced by leachates of solid wastes from flashlight battery, pigment, and tanning factories in the midgut cells and brain ganglia of Drosophila melanogaster mutants deficient in DNA repair proteins. Larvae were allowed to feed for 48 or 72 hr on diets containing 0.1, 0.5, and 2.0% (v/v) of the leachates. Physicochemical analysis run on the solid wastes, leachates, and treated larvae detected elevated levels of heavy metals. Leachates produced significantly greater levels of DNA damage in mutant strains mei41 (deficient in cell cycle check point protein), mus201 (deficient in excision repair protein), mus308 (deficient in postreplication repair protein), and rad54 (deficient in double strand break repair protein) than in the OregonR+ wild‐type strain. Larvae of the ligaseIV mutant (deficient in double strand break repair protein) were hypersensitive only to the pigment plant waste leachate. Conversely, the dnase2 mutant (deficient in protein responsible for degrading fragmented DNA) was more sensitive to DNA damage induction from the flashlight battery and tannery waste leachates. Our data demonstrate that repair of DNA damage in organisms exposed to leachates is dependent upon several DNA repair proteins, indicative of the involvement of multiple overlapping repair pathways. The study further suggests the usefulness of the Comet assay for studying the mechanisms of DNA repair in Drosophila. Environ. Mol. Mutagen., 2008. © 2008 Wiley‐Liss, Inc.