bluuebunny/crossref_metadata_2025_split huggingface dataset:
Reliability of the Ely's test for assessing rectus femoris muscle flexibility and joint range of motion
Authors: Peeler J. , Anderson J.E. 
Published: January 2008

AbstractRehabilitative protocols and orthopadic research are significantly influenced by the ability to perform reliable measures of specific physical attributes or functions. The hypothesis was that the Ely's test for evaluating rectus femoris flexibility and joint range of motion (ROM) is a reliable clinical tool. Participants (n = 54) were between the ages of 18 and 45, and had no history of trauma. Three clinicians with orthopedic expertise assessed quadriceps flexibility and joint ROM using pass/fail and goniometer scoring systems. A retest session was completed 7 to 10 days later. Statistically, Kappa values for pass/fail scoring (intrarater $\bar {X}=0.52$, interrater $\bar {X}=0.46$) and ICC values (intrarater $\bar {X}=0.69$, interrater $\bar {X}=0.66$) for goniometer data both indicated that the Ely's test demonstrated only moderate levels of intra‐ and interrater reliability. Measurement error values (SEM = 4°, ME = 4°, and CV = 3%) and Bland and Altman plots (with 95% Limits of Agreement) further demonstrated the degree of intrarater variance for each examiner when executing the Ely's test in a clinical setting. Results call into question the statistical reliability of the Ely's test, and provide clinicians with important information regarding the reliability limits of the Ely's test when used to clinically evaluate flexibility and joint ROM in a physically active population. More research is required to determine the variables that may confound statistical reliability of this orthopedic technique that is commonly used in a clinical setting to assess function about the thigh region. © 2008 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 26:793–799, 2008
Sharp by order estimates of solutions of a simplest singular boundary value problem
Authors: Chernyavskaya N. A. , Shuster L. A. 
Published: January 2008

AbstractWe consider a boundary value problem

equation image
where f ∈ Lp (ℝ), p ∈ [1, ∞] (L∞ (ℝ) ≔ C (ℝ)) and 0 ≤ q ∈ Lloc1 (ℝ). For a given p ∈ [1, ∞], for a correctly solvable problem (0.1) in Lp (ℝ), we obtain minimal requirements to a positive, continuous function Θ(x) for x ∈ ℝ under which, regardless of f ∈ Lp (ℝ), the solution y ∈ Lp (ℝ) of problem (0.1) satisfies the equality
equation image
. (© 2008 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
An infinite dimensional functional calculus in Banach algebras with a modulus
Authors: Dineen Séan , Harte Robin , Rivera Maria J. 
Published: January 2008

AbstractThe presence of a modulus function on a Banach algebra gives rise to tensor product norms analogous to the greatest cross‐norm and allows us to extend the Waelbroeck functional calculus. (© 2008 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
The group of self homotopy equivalences of some localized aspherical complexes
Authors: Garvín A. , Murillo A. , Remedios J. , Viruel A. 
Published: January 2008

AbstractBy studying the group of self homotopy equivalences of the localization (at a prime p and/or zero) of some aspherical complexes, we show that, contrary to the case when the considered space is a nilpotent, ℰm #(Xp ) is in general different from ℰm #(X)p. That is the case even when X = K (G, 1) is a finite complex and/or G satisfies extra finiteness or nilpotency conditions, for instance, when G is finite or virtually nilpotent. (© 2008 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
An extraordinary origami curve
Authors: Herrlich Frank , Schmithüsen Gabriela 
Published: January 2008

AbstractWe study the origami W defined by the quaternion group of order 8 and its Teichmüller curve C (W) in the moduli space M3. We prove that W has Veech group SL2(ℤ), determine the equation of the family over C (W) and find several further properties. As main result we obtain infinitely many origami curves in M3 that intersect C (W). We also present a combinatorial description of these origamis. (© 2008 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
On the principal eigenvalue of a Robin problem with a large parameter
Authors: Levitin Michael , Parnovski Leonid 
Published: January 2008

AbstractWe study the asymptotic behaviour of the principal eigenvalue of a Robin (or generalised Neumann) problem with a large parameter in the boundary condition for the Laplacian in a piecewise smooth domain. We show that the leading asymptotic term depends only on the singularities of the boundary of the domain, and give either explicit expressions or two‐sided estimates for this term in a variety of situations. (© 2008 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
Convolution operators on Lorentz spaces over locally compact Vilenkin groups
Authors: Quek T. S. 
Published: January 2008

AbstractLet G be a locally compact Vilenkin group. Using Herz spaces, we give sufficient conditions for a distribution on G to be a convolution operator on certain Lorentz spaces. Our results generalize Hörmander's multiplier theorem on G. (© 2008 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
Closed convex hulls, contents, and K‐spectral states
Authors: Thill Marco 
Published: January 2008

AbstractOur general result says that the closed convex hull of a set K consists of barycentres of probability contents (i.e., finitely additive set functions) on K. (Here K can be any nonempty subset of any nonempty compact convex set in any real or complex locally convex Hausdorff vector space.) In the equivalent setting of dual spaces, we give a very handy analytic criterion for a linear functional to be in the closed convex hull of a given nonempty point‐wise bounded set K of linear functionals (under some mild additional assumption). This is the notion of a K‐spectral state. Our criterion enhances the Abstract Bochner Theorem for unital commutative Banach *‐algebras (which easily follows from our result), in that it allows us to prescribe the set K on which a representing content should live. The content can be chosen to be a Radon measure if K is weak* compact. (© 2008 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
Existence of travelling wave solutions for the heat equation in infinite cylinders with a nonlinear boundary condition
Authors: Kyed Mads 
Published: January 2008

AbstractThe existence of travelling wave solutions for the heat equation ∂t u –Δu = 0 in an infinite cylinder subject to the nonlinear Neumann boundary condition (∂u /∂n) = f (u) is investigated. We show existence of nontrivial solutions for a large class of nonlinearities f. Additionally, the asymptotic behavior at ∞ is studied and regularity properties are established. We use a variational approach in exponentially weighted Sobolev spaces. (© 2008 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
Genetically confirmed Huntington's disease masquerading as motor neuron disease
Authors: Kanai Kazuaki , Kuwabara Satoshi , Sawai Setsu , Nakata Miho , Misawa Sonoko , Isose Sagiri , Hirano Shigeki , Kawaguchi Naoki , Katayama Kaoru , Hattori Takamichi 
Published: January 2008

AbstractWe describe a patient with Huntington's disease (HD) who showed asymmetrical upper limb amyotrophy as a main manifestation. Chorea and psychiatric symptoms were not prominent. Electromyography revealed generalized active and chronic denervation and fasciculations. A genetic test showed 46 CAG repeats in the huntingtin gene. Asymmetrical amyotrophy restricted to the upper limb has been reported in some patients with progressive chorea and amyotrophy without acanthocytosis, but genetically proven cases of HD have rarely been reported. It is not known why only a few HD patients show the motor neuronal loss; however, certain as‐yet‐unidentified genetic factors combined with some environment factors and the underlying cellular dysfunctions by polyglutamine aggregation could be responsible for the motor neuronal loss similar to that in amyotrophic lateral sclerosis. © 2008 Movement Disorder Society
Assessing the needs of pregnant women and mothers with severe mental illness: the psychometric properties of the Camberwell Assessment of Need – Mothers (CAN‐M)
Authors: Howard L. , Hunt K. , Slade M. , O'Keane V. , Senevirante T. , Leese M. , Thornicroft G. 
Published: January 2008

AbstractThere is an absence of standardized validated instruments to assess the complex needs of pregnant women and mothers with severe mental illness. We aimed to develop a standardized assessment of need for pregnant women and mothers with severe mental illness. Staff and service users were asked to identify relevant domains of need. Professional experts and service users were then surveyed and asked to rate the importance of the domains of the Camberwell Assessment of Need – Mothers version (CAN‐M). Reliability was established using 36 service user–staff pairs. Concurrent validity was assessed with the Global Assessment of Functioning. Inter‐rater reliability (concordance) coefficients for unmet needs were 0.93 (95% confidence interval 0.89 to 0.98) (service users) and 0.83 (95% confidence interval 0.73 to 0.94) (staff); test–retest reliability coefficients were 0.91 (95% confidence interval 0.86 to 0.97) and 0.85 (95% confidence interval 0.73 to 0.96), respectively. Relevant CAN‐M domains correlated with the Global Assessment of Functioning‐symptom (Spearman's r correlation coefficient = −0.36, 95% confidence interval = −0.62 to −0.04, p = 0.05) and Global Assessment of Functioning‐disability subscales (Spearman's r correlation coefficient = −0.52, confidence interval = −0.73 to −0.23, p < 0.01).We conclude that the CAN‐M is a reliable and valid instrument for assessing the needs of pregnant women and mothers with severe mental illness. Copyright © 2008 John Wiley & Sons, Ltd.
Gender differences in the prediction of 5‐year outcome in first episode psychosis
Authors: Mattsson Maria , Flyckt Lena , Edman Gunnar , Nyman Håkan , Cullberg Johan , Forsell Yvonne 
Published: January 2008

AbstractObjective: To examine gender differences in prediction of long‐term outcome in first episode psychosis (FEP).Method: Eighty‐one male and 72 female FEP patients were compared regarding the sensitivity and specificity of the Predictive Rating Scale (PRS). The contributions of pre‐admission clinical and socio‐demographic characteristics to a poor 5‐year outcome were analysed for males and females separately. Gender differences in the relations between predictors and outcome were examined using the equality of correlation comparing correlation coefficients.Results: The sensitivity of the PRS was significantly better for males than for females. The following items: ‘the highest Global Assessment of Functioning (GAF) the year before first admission ≤70’ and ‘GAF at first admission ≤30’ explained most of the variance of a poor 5‐year outcome for males, whereas for females the corresponding items were ‘the highest educational level is compulsory school’, ‘living with parents’ and ‘contact with friends ≤2–3 times/month’. When the PRS was adapted assigning a weight of two to the item ‘the highest educational level is compulsory school’ for females, the sensitivity increased.Conclusion: This study revealed that the predictors for poor outcome differ between male and female patients with FEP. Copyright © 2008 John Wiley & Sons, Ltd.
Technical note: Reexamination of all‐or‐none inspection policies in a supply chain with endogenous product quality
Authors: Wan Hong , Xu Xiaowei 
Published: January 2008

AbstractThis note studies the optimal inspection policies in a supply chain in which a manufacturer purchases components from a supplier but has no direct control of component quality. The manufacturer uses an inspection policy and a damage cost sharing contract to encourage the supplier to improve the component quality. We find that all‐or‐none inspection policies are optimal for the manufacturer if the supplier's share of the damage cost is larger than a threshold; otherwise, the manufacturer should inspect a fraction of a batch. © 2008 Wiley Periodicals, Inc. Naval Research Logistics, 2008
A fast algorithm for computing the smallest eigenvalue of a symmetric positive‐definite Toeplitz matrix
Authors: Mastronardi N. , Van Barel M. , Vandebril R. 
Published: January 2008

AbstractRecent progress in signal processing and estimation has generated considerable interest in the problem of computing the smallest eigenvalue of a symmetric positive‐definite (SPD) Toeplitz matrix.An algorithm for computing upper and lower bounds to the smallest eigenvalue of a SPD Toeplitz matrix has been recently derived (Linear Algebra Appl. 2007; DOI: 10.1016/j.laa.2007.05.008). The algorithm relies on the computation of the R factor of the QR factorization of the Toeplitz matrix and the inverse of R. The simultaneous computation of R and R−1 is efficiently accomplished by the generalized Schur algorithm. In this paper, exploiting the properties of the latter algorithm, a numerical method to compute the smallest eigenvalue and the corresponding eigenvector of SPD Toeplitz matrices in an accurate way is proposed. Copyright © 2008 John Wiley & Sons, Ltd.
Use of the combined first‐trimester screen result and low PAPP‐A to predict risk of adverse fetal outcomes
Authors: Barrett Sandie L. , Bower Carol , Hadlow Narelle C. 
Published: January 2008

AbstractObjectivesTo investigate associations between combined first‐trimester screen result, pregnancy associated plasma protein‐A (PAPP‐A) level and adverse fetal outcomes in women.MethodsPregnancy outcomes for 10 273 women participating in a community based first‐trimester screening (FTS) programme in Western Australia were ascertained by record linkage to birth and birth defect databases. A first‐trimester risk cut‐off of ≥ 1 in 300 defined screen positive women.ResultsScreen positive pregnancies were more likely to have Down syndrome and birth defects (chromosomal or nonchromosomal) than screen negative pregnancies. When birth defects were excluded, screen positive pregnancies were at increased risk of pregnancy loss, low birth weight and preterm birth. Pregnancies with low PAPP‐A (⩽0.3 multiples of the median (MoM)) had higher risk of chromosomal abnormality, birth defect, preterm birth, low birth weight, or pregnancy loss, compared to those with PAPP‐A > 0.3 MoM. In pregnancies without birth defects, low PAPP‐A was a stronger predictor of preterm birth, low birth weight or pregnancy loss than a screen positive result.ConclusionsWomen with positive screen or low PAPP‐A were at increased risk for some adverse fetal outcomes. The sensitivity of these parameters was insufficient to support primary screening, but increased surveillance during pregnancy may be appropriate. Copyright © 2008 John Wiley & Sons, Ltd.
Nonvisualization of the fetal gallbladder by second‐trimester ultrasound scan: strategy of clinical management based on four examples
Authors: Boughanim Mathias , Benachi Alexandra , Dreux Sophie , Delahaye Sophie , Muller Françoise 
Published: January 2008

AbstractObjectiveWhen the fetal gallbladder is not seen at ultrasound (US) scan, to propose a diagnostic method of differentiating fetuses who are healthy or have minor anomalies from fetuses with severe anomalies requiring intensive management.MethodWe present four clinical cases illustrating this variability, together with additional examinations: karyotyping, screening for cystic fibrosis mutations, amniotic fluid digestive enzyme activities.ResultsThe four examples we present‐biliary duct atresia, biliary agenesis, gallbladder reveal at birth, and cystic fibrosis‐illustrate the difficulties of making both diagnosis and prognosis prenatally when the gallbladder is not visualized. Laboratory assays allowed prenatal management.ConclusionFailure to visualize the gallbladder prenatally may indicate fetal diseases of highly variable prognosis, but may also sometimes be followed by postnatal visualization in a child free of any disease. Prenatal management could help in defining diagnosis and prognosis. Copyright © 2008 John Wiley & Sons, Ltd.
First‐trimester maternal placental protein 13 levels in pregnancies resulting in adverse outcomes
Authors: Cowans Nicholas J. , Spencer Kevin , Meiri Hamutal 
Published: January 2008

AbstractBackgroundIn a previous study, reduced levels of maternal serum placental protein 13 (PP13) in the first trimester have been correlated with adverse pregnancy outcomes. The objective of this study was to compare first‐trimester PP13 levels in control pregnancies with pregnancies resulting in one or more of the following adverse outcomes: intrauterine growth restriction (IUGR), small and very small (3rd, 5th, 10th centile) for gestational age (SGA), low (<1.5 and < 2.5 kg) birth weight (LBW), macrosomia (the > 90th centile), large birth weight (>4.5 kg), preterm (35–36 weeks) and very early (<34 weeks) delivery (PTD), and intrauterine fetal demise (IUFD).MethodsMaternal serum samples from 1940, 11 to 14 weeks singleton pregnancies, were assayed for PP13 and the concentrations were corrected for gestational age, maternal weight, smoking status, and ethnic origin. A comparison of the levels of PP13 in 364 controls and 1576 adverse outcome categories was made. PP13 levels were expressed in terms of both concentration and multiple of medians (MoMs).ResultsComparison of PP13 MoMs from SGA, PTD, and low birth weight samples with control pregnancy samples showed no statistically significant difference. In macrosomic pregnancies (>90th centile), levels of PP13 were significantly higher than controls (p = 0.0263) although the number of cases in this study was small.ConclusionDecreased levels of PP13 were not significantly correlated with the studied adverse pregnancy outcomes of IUGR, PTD low birth weight, and IUFD. Further studies are required to evaluate if measurement of PP13 has any value in the early assessment of pregnancies. Copyright © 2008 John Wiley & Sons, Ltd.
Moderate and high affinity serotonin reuptake inhibitors increase the risk of upper gastrointestinal toxicity
Authors: Lewis James D. , Strom Brian L. , Localio A. Russell , Metz David C. , Farrar John T. , Weinrieb Robert M. , Nessel Lisa , Brensinger Colleen , Kimmel Stephen E. 
Published: January 2008

AbstractObjectiveSerotonin release from platelets is important for regulating hemostasis. Some prior studies suggest an association between use of selective serotonin reuptake inhibitors and gastrointestinal bleeding and a possible synergistic effect of these medications with non‐steroidal anti‐inflammatory drugs (NSAIDs). This study examined the effect of medications that inhibit serotonin uptake on upper gastrointestinal toxicity.Methods359 case subjects hospitalized for upper gastrointestinal bleeding, perforation, or benign gastric outlet obstruction were recruited from 28 hospitals. 1889 control subjects were recruited by random digit dialing from the same region. Data were collected during structured telephone interviews. Antidepressant medications were characterized according to their affinity for serotonin receptors. Exposure to medications required use on at least 1 day during the week prior to the index date.ResultsAny moderate or high affinity serotonin reuptake inhibitor (MHA‐SRI) use was reported by 61 cases (17.1%) and 197 controls (10.4%). After adjusting for potential confounders, MHA‐SRI use was associated with a significantly increased odds of hospitalization for upper gastrointestinal toxicity (adjusted OR = 2.0, 95%CI 1.4–3.0). A dose–response relationship in terms of affinity for serotonin uptake receptors was not observed (p = 0.17). No statistical interaction was observed for use of high dose NSAIDs or aspirin concomitantly with MHA‐SRIs (p = 0.5). When MHA‐SRIs were used concomitantly with high dose NSAIDs, the adjusted odds ratio for the association with upper gastrointestinal toxicity was 3.5 (95%CI 1.9–6.6).ConclusionsUse of MHA‐SRIs is associated with an increased risk of hospitalization for upper gastrointestinal toxicity. Copyright © 2008 John Wiley & Sons, Ltd.
Protein–protein docking by simulating the process of association subject to biochemical constraints
Authors: Motiejunas Domantas , Gabdoulline Razif , Wang Ting , Feldman‐Salit Anna , Johann Tim , Winn Peter J. , Wade Rebecca C. 
Published: January 2008

AbstractWe present a computational procedure for modeling protein–protein association and predicting the structures of protein–protein complexes. The initial sampling stage is based on an efficient Brownian dynamics algorithm that mimics the physical process of diffusional association. Relevant biochemical data can be directly incorporated as distance constraints at this stage. The docked configurations are then grouped with a hierarchical clustering algorithm into ensembles that represent potential protein–protein encounter complexes. Flexible refinement of selected representative structures is done by molecular dynamics simulation. The protein–protein docking procedure was thoroughly tested on 10 structurally and functionally diverse protein–protein complexes. Starting from X‐ray crystal structures of the unbound proteins, in 9 out of 10 cases it yields structures of protein–protein complexes close to those determined experimentally with the percentage of correct contacts >30% and interface backbone RMSD <4 Å. Detailed examination of all the docking cases gives insights into important determinants of the performance of the computational approach in modeling protein–protein association and predicting of protein–protein complex structures. Proteins 2008. © 2008 Wiley‐Liss, Inc.
The type IA topoisomerase catalytic cycle: A normal mode analysis and molecular dynamics simulation
Authors: Xiong Bing , Burk David L. , Shen Jianhua , Luo Xiaomin , Liu Hong , Shen Jingkang , Berghuis Albert M. 
Published: January 2008

AbstractType IA topoisomerases alter the topological state of DNA to relax the supercoils introduced during the DNA replication and transcription process, giving them critical roles in many cellular functions. To manipulate the DNA, type IA topoisomerases first cleave one DNA strand and form a covalent linkage between a catalytic tyrosine residue and the 5′‐phosphoryl of the DNA. This is followed by a movement of domain III of the topoisomerase to accommodate the second DNA strand in the center channel of the topoisomerase. Domain III is then closed for religation of the cleaved DNA and subsequently reopened to release the passing strand. Although numerous biophysical and biochemical studies have examined this catalytic cycle, fundamental questions remain such as how domain III opens and closes during this process. We have used computational simulation methods, namely normal mode analysis and molecular dynamics, to investigate the catalytic cycle of Escherichia coli topoisomerase III as a representative of the type IA topoisomerases. It was found that domain II is intrinsically flexible and may empower the enzyme to perform its function by triggering domain III opening and closing. A molecular dynamics simulation and MM‐PBSA analysis shows that topoisomerase III alone cannot overcome the large energy barrier of the conformational transition. A detailed examination of the DNA binding sites suggests that the processing DNA cooperates with the topoisomerase to accomplish this dramatic conformational change. These findings will guide future mutagenesis studies of type IA topoisomerases aimed at dissecting the driving forces and conformations in the catalytic cycle. Proteins 2008. © 2008 Wiley‐Liss, Inc.