bluuebunny/crossref_metadata_2025_split huggingface dataset:
Asymmetric fin shape changes swimming dynamics of ancient marine reptiles’ soft robophysical models
Authors: Sprumont Hadrien , Allione Federico , Schwab Fabian , Wang Bingcheng , Mucignat Claudio , Lunati Ivan , Scheyer Torsten , Ijspeert Auke , Jusufi Ardian 
Published: April 2024

Abstract
Animals have evolved highly effective locomotion capabilities in terrestrial, aerial, and aquatic environments. Over life’s history, mass extinctions have wiped out unique animal species with specialized adaptations, leaving paleontologists to reconstruct their locomotion through fossil analysis. Despite advancements, little is known about how extinct megafauna, such as the Ichthyosauria one of the most successful lineages of marine reptiles, utilized their varied morphologies for swimming. Traditional robotics struggle to mimic extinct locomotion effectively, but the emerging soft robotics field offers a promising alternative to overcome this challenge. This paper aims to bridge this gap by studying Mixosaurus locomotion with soft robotics, combining material modeling and biomechanics in physical experimental validation. Combining a soft body with soft pneumatic actuators, the soft robotic platform described in this study investigates the correlation between asymmetrical fins and buoyancy by recreating the pitch torque generated by extinct swimming animals. We performed a comparative analysis of thrust and torque generated by Carthorhyncus, Utatsusaurus, Mixosaurus, Guizhouichthyosaurus, and Ophthalmosaurus tail fins in a flow tank. Experimental results suggest that the pitch torque on the torso generated by hypocercal fin shapes such as found in model systems of Guizhouichthyosaurus, Mixosaurus and Utatsusaurus produce distinct ventral body pitch effects able to mitigate the animal’s non-neutral buoyancy. This body pitch control effect is particularly pronounced in Guizhouichthyosaurus, which results suggest would have been able to generate high ventral pitch torque on the torso to compensate for its positive buoyancy. By contrast, homocercal fin shapes may not have been conducive for such buoyancy compensation, leaving torso pitch control to pectoral fins, for example. Across the range of the actuation frequencies of the caudal fins tested, resulted in oscillatory modes arising, which in turn can affect the for-aft thrust generated.
Air quality and heath co-benefits of low carbon transition policies in electricity system: the case of Beijing–Tianjin–Hebei region
Authors: Guo Zheng-Quan , Zhang Jia-Qi , Zhang Wen-Wen , Zhao Bin , Jiang Yue-Qi , Wang Shu-Xiao , Sheng Xin-Yi , Wu Yi , Chen Xia-Qing , Rao Lan-Lan , Nie Jian-Yun 
Published: April 2024

Abstract
Low carbon transition strategies of power plants are crucial to meet China’s ‘Dual Carbon’ targets. While the Beijing–Tianjin–Hebei (BTH) region, the ‘capital economic circles’ of China, is suffering from serious air pollution, air quality co-benefits of low carbon transition policies in electricity system in BTH area remain unclear. Here, we estimate the impacts of low carbon transition policies, including one BAU, six single and five combined scenarios, in electricity system in BTH area on installed power capacity, CO2 emissions, air quality and human health through 2060 based on open source energy modeling system and extend response surface model ERSM models. Results show that the total installed capacity under single and combined scenarios (except RE and Tech single scenarios) fluctuates around the BAU level of 310.5 GW in 2060. While all single and combined scenarios would generally achieve ‘carbon peak’ in BTH electricity system before 2030, only S4 (combining technological progress, renewable energy development and CCUS) and S5 (in additional to S4, including gas-fired power generation instead of coal-fired power generation) scenarios have the potential to realize carbon neutrality by 2060. The magnitude of reductions in air pollutant emissions and improvement in air quality in BTH area from the BAU level in 2060 under combined scenarios, especially S4 and S5, generally exceed that of six single scenarios. Importantly, S5 in 2060 contributes to about 8528 avoided premature mortalities in BTH area, which are more effective than any other scenarios. The results suggest that S5 is a promising low carbon transition policy to achieve environmental improvement and produce health benefits.
The emergence of cooperation via Q-learning in spatial donation game
Authors: Zhang Jing , Rong Zhihai , Zheng Guozhong , Zhang Jiqiang , Chen Li 
Published: April 2024

Abstract
Decision-making often overlooks the feedback between agents and the environment. Reinforcement learning is widely employed through exploratory experimentation to address problems related to states, actions, rewards, decision-making in various contexts. This work considers a new perspective, where individuals continually update their policies based on interactions with the spatial environment, aiming to maximize cumulative rewards and learn the optimal strategy. Specifically, we utilize the Q-learning algorithm to study the emergence of cooperation in a spatial population playing the donation game. Each individual has a Q-table that guides their decision-making in the game. Interestingly, we find that cooperation emerges within this introspective learning framework, and a smaller learning rate and higher discount factor make cooperation more likely to occur. Through the analysis of Q-table evolution, we disclose the underlying mechanism for cooperation, which may provide some insights to the emergence of cooperation in the real-world systems.
Connecting people with place-specific nature in cities reduces unintentional harm
Authors: Stanley Margaret C , Galbraith Josie A 
Published: April 2024

Abstract
There is an increasing disconnect between people and nature as we become more urbanised. Intensification in cities often results in a reduction of natural areas, more homogenised and manicured green spaces, and loss of biota. Compared to people in rural areas, urban dwellers are less likely visit natural areas and recognise and value biota. Reconnecting people with nature in the city not only benefits human mental and physical wellbeing but can also have positive effects on how people value biodiversity and act on conservation issues. However, in some contexts, the push to reconnect people with nature may have unintended negative outcomes on biodiversity, particularly if place-specific nature is not used in urban greening. In the current biodiversity crisis, using vegetation and green space design that is not reflective of the environmental context of a city can further disconnect residents, particularly Indigenous people, from their local environment and species, and further entrench extinction of experience and loss of environmental values. This disconnect can result in residents applying wildlife gardening practices, such as bird feeding, that are not specific to place, and benefit introduced species over indigenous species. Furthermore, cities are gateways for invasive species, and using species in greening projects that are not locally sourced has already left cities and their surrounding regions with a large weed legacy. Using place-specific nature and green space in cities can be less resource intensive, highly beneficial for biodiversity and give residents a unique sense of place. Rather than simply adding ‘more nature’ in cities, the messaging should be more complex, emphasising the need for urban greening to be context specific to avoid negative impacts on biodiversity and ecological and cultural services.
Deficiency of β-xylosidase activity in Aspergillus luchuensis mut. kawachii IFO 4308
Authors: Zhu Enkang , Hiramatsu Kentaro , Inoue Taiga , Mori Kazuki , Tashiro Kosuke , Fujita Kiyotaka , Karashima Takefumi , Takashita Hideharu , Okutsu Kayu , Yoshizaki Yumiko , Takamine Kazunori , Tamaki Hisanori , Futagami Taiki 
Published: April 2024

ABSTRACT
In this study, we investigated a deleterious mutation in the β-xylosidase gene, xylA (AkxylA), in Aspergillus luchuensis mut. kawachii IFO 4308 by constructing an AkxylA disruptant and complementation strains of AkxylA and xylA derived from A. luchuensis RIB2604 (AlxylA), which does not harbor the mutation in xylA. Only the AlxylA complementation strain exhibited significantly higher growth and substantial β-xylosidase activity in medium containing xylan, accompanied by an increase in XylA expression. This resulted in lower xylobiose and higher xylose concentrations in the mash of barley shochu. These findings suggest that the mutation in xylA affects xylose levels during the fermentation process. Because the mutation in xylA was identified not only in the genome of strain IFO 4308 but also the genomes of other industrial strains of A. luchuensis and A. luchuensis mut. kawachii, these findings enhance our understanding of the genetic factors that affect the fermentation characteristics.
Trajectory of primordial follicle depletion is accelerated in obese mice in response to 7,12-dimethylbenz[a]anthracene exposure
Authors: Rishi Jaspreet K , Timme Kelsey , White Hunter E , Kerns Karl C , Keating Aileen F 
Published: April 2024

Abstract
Both obesity and exposure to environmental genotoxicants, such as 7,12-dimethylbenz[a]anthracene, negatively impair female reproductive health. Hyperphagic lean KK.Cg-a/a (n = 8) and obese KK.Cg-Ay/J (n = 10) mice were exposed to corn oil as vehicle control (CT) or 7,12-dimethylbenz[a]anthracene (1 mg/kg/day) for 7d intraperitoneally, followed by a recovery period. Obesity increased liver and spleen weight (P &lt; 0.05), and 7,12-dimethylbenz[a]anthracene exposure decreased uterine weight (P &lt; 0.05) in obese mice. Primordial follicle loss (P &lt; 0.05) caused by 7,12-dimethylbenz[a]anthracene exposure was observed in obese mice only. Primary (lean P &lt; 0.1; obese P &lt; 0.05) and secondary (lean P &lt; 0.05, obese P &lt; 0.1) follicle loss initiated by 7,12-dimethylbenz[a]anthracene exposure continued across recovery. Reduced pre-antral follicle number in lean mice (P &lt; 0.05), regardless of 7,12-dimethylbenz[a]anthracene exposure, was evident with no effect on antral follicles or corpora lutea number. Immunofluorescence staining of DNA damage marker, γH2AX, did not indicate ongoing DNA damage but TRP53 abundance was decreased in follicles (P &lt; 0.05) of 7,12-dimethylbenz[a]anthracene-exposed obese mice. In contrast, increased (P &lt; 0.05) superoxide dismutase was observed in the corpora lutea of 7,12-dimethylbenz[a]anthracene-exposed obese mice and reduced (P &lt; 0.05) TRP53 abundance was noted in preantral and antral follicles of 7,12-dimethylbenz[a]anthracene-exposed obese mice. This study indicates that obesity influences ovotoxicity caused by a genotoxicant, potentially involving accelerated primordial follicle activation and hampering normal follicular dynamics.
Phylogeny, chronology, and phylogeography in Australasian Hypnodendraceae
Authors: Sánchez-Ganfornina Diego , Bell Neil E 
Published: April 2024

Abstract
The Hypnodendrales form the sister group to all other pleurcarpous mosses in the superorder Hypnanae. Many species are closely associated with the cool temperate rainforests of Australasia, while others are widespread in higher altitude wet forests across tropical South-East Asia. Several of the Malesian entities are taxonomically ambiguous, having been variously treated as species complexes or as single very variable species.
Here we use dated phylogenies to examine the timing of diversification of major clades within the Hypnodendrales, test the hypothesis that widespread, taxonomically problematic species have diversified relatively recently in South-East Asia from within clades of southern temperate origin, and address taxonomic questions within Hypnodendron. A chronogram with broad taxonomic sampling is constructed, followed by a second dated phylogeny with dense sampling from Hypnodendron vitiense, a representative morphologically variable species found throughout Eastern Australia and South-East Asia.
The crown group Hypnodendrales are found to have originated in the mid-Cretaceous, although they share a Most Recent Common Ancestor (MRCA) with the other Hypnanae in the late Jurassic. Extant members of Hypnodendron share a MRCA ±28 Mya, a little before the start of the collision of Australia with the Sunda plate that initiated the Australasian–Malesian floristic interchange. Within H. vitiense, there is strong phylogenetic structure consistent with the diversification and isolation of populations in South-East Asia within the last 10 Mya. The New Zealand endemic H. marginatum is found to be derived from within an Australasian clade of H. vitiense, this in turn being distinct from a South-East Asian/tropical Australian H. vitiense clade. Our results suggest that the phylogeography of this prominent group of mosses closely mirrors that of the rainforest ecosystems of which they are a part.
Endothelial nucleotide-binding oligomerization domain-like receptor protein 3 inflammasome regulation in atherosclerosis
Authors: Guo Shuai , Wang Litao , Cao Kaixiang , Li Ziling , Song Mingchuan , Huang Shuqi , Li Zou , Wang Cailing , Chen Peiling , Wang Yong , Dai Xiaoyan , Chen Xianglin , Fu Xiaodong , Feng Du , He Jun , Huo Yuqing , Xu Yiming 
Published: April 2024

Abstract

Aims
The activation of nucleotide-binding oligomerization domain-like receptor protein 3 (NLRP3) inflammasome in endothelial cells (ECs) contributes to vascular inflammation in atherosclerosis. Considering the high glycolytic rate of ECs, we delineated whether and how glycolysis determines endothelial NLRP3 inflammasome activation in atherosclerosis.

Methods and results
Our results demonstrated a significant up-regulation of 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 (PFKFB3), a key regulator of glycolysis, in human and mouse atherosclerotic endothelium, which positively correlated with NLRP3 levels. Atherosclerotic stimuli up-regulated endothelial PFKFB3 expression via sterol regulatory element-binding protein 2 (SREBP2) transactivation. EC-selective haplodeficiency of Pfkfb3 in Apoe−/− mice resulted in reduced endothelial NLRP3 inflammasome activation and attenuation of atherogenesis. Mechanistic investigations revealed that PFKFB3-driven glycolysis increased the NADH content and induced oligomerization of C-terminal binding protein 1 (CtBP1), an NADH-sensitive transcriptional co-repressor. The monomer form, but not the oligomer form, of CtBP1 was found to associate with the transcriptional repressor Forkhead box P1 (FOXP1) and acted as a transrepressor of inflammasome components, including NLRP3, caspase-1, and interleukin-1β (IL-1β). Interfering with NADH-induced CtBP1 oligomerization restored its binding to FOXP1 and inhibited the glycolysis-dependent up-regulation of NLRP3, Caspase-1, and IL-1β. Additionally, EC-specific overexpression of NADH-insensitive CtBP1 alleviates atherosclerosis.

Conclusion
Our findings highlight the existence of a glycolysis-dependent NADH/CtBP/FOXP1-transrepression pathway that regulates endothelial NLRP3 inflammasome activation in atherogenesis. This pathway represents a potential target for selective PFKFB3 inhibitors or strategies aimed at disrupting CtBP1 oligomerization to modulate atherosclerosis.
nhanesA: achieving transparency and reproducibility in NHANES research
Authors: Ale Laha , Gentleman Robert , Sonmez Teresa Filshtein , Sarkar Deepayan , Endres Christopher 
Published: April 2024

Abstract
The National Health and Nutrition Examination Survey provides comprehensive data on demographics, sociology, health and nutrition. Conducted in 2-year cycles since 1999, most of its data are publicly accessible, making it pivotal for research areas like studying social determinants of health or tracking trends in health metrics such as obesity or diabetes. Assembling the data and analyzing it presents a number of technical and analytic challenges. This paper introduces the nhanesA R package, which is designed to assist researchers in data retrieval and analysis and to enable the sharing and extension of prior research efforts. We believe that fostering community-driven activity in data reproducibility and sharing of analytic methods will greatly benefit the scientific community and propel scientific advancements.
Database URL: https://github.com/cjendres1/nhanes
Association between alcohol consumption and peripheral artery disease: two de novo prospective cohorts and a systematic review with meta-analysis
Authors: Yuan Shuai , Wu Jing , Chen Jie , Sun Yuhao , Burgess Stephen , Li Xue , Åkesson Agneta , Larsson Susanna C 
Published: April 2024

Abstract

Aims
The association between alcohol consumption and risk of peripheral artery disease (PAD) is inconclusive. We conducted this study to examine the association between alcohol consumption and PAD risk in two de novo cohort studies and a meta-analysis of observational studies.

Methods and results
A systematic review was conducted to identify studies on alcohol consumption in relation to PAD risk. We further used data from two cohorts of 70 116 Swedish and 405 406 British adults and performed a meta-analysis of results from previously published studies and current cohort studies. There was a U-shaped association between alcohol consumption and incident PAD risk in the Swedish and British cohorts. The meta-analysis of results of these two cohorts and previously published studies found that compared with non- or never-drinkers, the relative risk of PAD was 0.83 [95% confidence interval (CI) 0.77–0.89], 0.81 (95% CI 0.74–0.90), and 0.94 (95% CI 0.83–1.07) for light, moderate, and high-to-heavy alcohol drinkers, respectively. The nonlinear meta-analysis revealed a possibly U-shaped association between alcohol consumption and PAD risk (P nonlinearity &lt;0.001). The risk of PAD was observed to be the lowest for 2 drinks/week and to be pronounced for ≥10 drinks/week. All these associations persisted in a sensitivity meta-analysis including cohort and other types of observational studies.

Conclusion
Alcohol intake ≤2 drinks/week was associated with a reduced risk of PAD, and the risk of PAD became pronounced with intake ≥10 drinkers/week.
Interaction between phytoplankton and heterotrophic bacteria in Arctic fjords during the glacial melting season as revealed by eDNA metabarcoding
Authors: Han Dukki , Park Ki-Tae , Kim Haryun , Kim Tae-Hoon , Jeong Man-Ki , Nam Seung-Il 
Published: April 2024

Abstract
The hydrographic variability in the fjords of Svalbard significantly influences water mass properties, causing distinct patterns of microbial diversity and community composition between surface and subsurface layers. However, surveys on the phytoplankton-associated bacterial communities, pivotal to ecosystem functioning in Arctic fjords, are limited. This study investigated the interactions between phytoplankton and heterotrophic bacterial communities in Svalbard fjord waters through comprehensive eDNA metabarcoding with 16S and 18S rRNA genes. The 16S rRNA sequencing results revealed a homogenous community composition including a few dominant heterotrophic bacteria across fjord waters, whereas 18S rRNA results suggested a spatially diverse eukaryotic plankton distribution. The relative abundances of heterotrophic bacteria showed a depth-wise distribution. By contrast, the dominant phytoplankton populations exhibited variable distributions in surface waters. In the network model, the linkage of phytoplankton (Prasinophytae and Dinophyceae) to heterotrophic bacteria, particularly Actinobacteria, suggested the direct or indirect influence of bacterial contributions on the fate of phytoplankton-derived organic matter. Our prediction of the metabolic pathways for bacterial activity related to phytoplankton-derived organic matter suggested competitive advantages and symbiotic relationships between phytoplankton and heterotrophic bacteria. Our findings provide valuable insights into the response of phytoplankton-bacterial interactions to environmental changes in Arctic fjords.
Robustness in population-structure and demographic-inference results derived from the Aedes aegypti genotyping chip and whole-genome sequencing data
Authors: Gómez-Palacio Andrés , Morinaga Gen , Turner Paul E , Micieli Maria Victoria , Elnour Mohammed-Ahmed B , Salim Bashir , Surendran Sinnathamby Noble , Ramasamy Ranjan , Powell Jeffrey R , Soghigian John , Gloria-Soria Andrea 
Published: April 2024

Abstract
The mosquito Aedes aegypti is the primary vector of many human arboviruses such as dengue, yellow fever, chikungunya, and Zika, which affect millions of people worldwide. Population genetic studies on this mosquito have been important in understanding its invasion pathways and success as a vector of human disease. The Axiom aegypti1 SNP chip was developed from a sample of geographically diverse A. aegypti populations to facilitate genomic studies on this species. We evaluate the utility of the Axiom aegypti1 SNP chip for population genetics and compare it with a low-depth shotgun sequencing approach using mosquitoes from the native (Africa) and invasive ranges (outside Africa). These analyses indicate that results from the SNP chip are highly reproducible and have a higher sensitivity to capture alternative alleles than a low-coverage whole-genome sequencing approach. Although the SNP chip suffers from ascertainment bias, results from population structure, ancestry, demographic, and phylogenetic analyses using the SNP chip were congruent with those derived from low-coverage whole-genome sequencing, and consistent with previous reports on Africa and outside Africa populations using microsatellites. More importantly, we identified a subset of SNPs that can be reliably used to generate merged databases, opening the door to combined analyses. We conclude that the Axiom aegypti1 SNP chip is a convenient, more accurate, low-cost alternative to low-depth whole-genome sequencing for population genetic studies of A. aegypti that do not rely on full allelic frequency spectra. Whole-genome sequencing and SNP chip data can be easily merged, extending the usefulness of both approaches.
New energy power demand prediction and optimal scheduling based on artificial intelligence in smart grid
Authors: Duan Jie 
Published: April 2024

Abstract
With the development of smart grid, the demand for new energy power increases. Improving the accuracy of new energy power demand forecast is an important basis for the orderly operation of power system. This article presents a new energy power demand forecasting method based on DESSA-NESN algorithm. First, differential evolution algorithm (DE) and sparrow search algorithm (SSA) are combined, and operations such as mutation, crossing and screening are introduced into the population updating process of SSA. The internal state function of the savings pool of the standard echo state network (ESN) is replaced by the hyperbolic tangent function to obtain the nonlinear echo state network (NESN). Then, the parameters of deep echo state network (DESN) are optimized using DESSA algorithm. The DESSA-DESN prediction model is established. Finally, the mean absolute percentage error (MAPE) and root mean square error (RMSE) of DESSA-NESN were 15.84 and 0.12%, respectively, and the prediction effect was better than other comparison models.