bluuebunny/crossref_metadata_2025_split huggingface dataset:
1,2,3,4‐Tetraethynylbenzene as a Template for Cobalt‐Catalyzed Alkyne Cocyclizations: Synthesis of 2,3,8,9‐Tetrakis(trimethylsilyl) Angular [3]Phenylene (Ia) and Bent [5]Phenylene (Benzo[1′′,2′′:3,4;3′′,4′′:3′,4′]dicyclobuta [1,2‐b:1′,2′‐b′]bisbiphenylene) (IIb).
Authors: Mohler Debra L. , Kumaraswamy Sriram , Stanger Amnon , Vollhardt K. Peter C. 
Published: February 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Thermolysis of Some Spirobenzopyran‐3′,2‐[1,3,4]oxadithiino[5,6‐c]benzopyran‐4′‐ones in the Presence of Some Homodienes and Crystallographic Studies of Some Adducts.
Authors: Hegab Mohamed I. , Moustafa A. M. 
Published: February 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Rh‐Catalyzed Alkene Oxidation: A Highly Efficient and Selective Process for Preparing N‐Alkoxysulfonyl Aziridines.
Authors: Guthikonda Kiran , Wehn Paul M. , Caliando Brian J. , Du Bois J. 
Published: February 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Synthesis of Bis‐ and Tetrakis‐(ω‐dimethylamino)‐Substituted Cross‐Conjugated Polyene α‐Diketones of the Thiophene Series.
Authors: Krasnaya Zh. A. , Smirnova Yu. V. , Tatikolov A. S. , Kolotaev A. V. 
Published: February 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Synthesis of N‐Aryl‐Substituted Pyrroles via γ‐Bromodypnone (I).
Authors: Potikha L. M. , Kovtunenko V. A. 
Published: February 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Novel Formation of 1,2‐Dithiolane‐3‐thione from β‐Dithiolactone.
Authors: Shigetomi Toshiyuki , Nojima Akiko , Shioji Kosei , Okuma Kentaro , Yokomori Yoshinobu 
Published: February 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Phase Transfer Catalyzed Acylation of 5(3)‐Hydroxy‐3(5)‐substituted‐1H‐pyrazoles.
Authors: Khalil Ali Kh. , Hassan Mohamed A. , Mohamed Mohamed M. , El‐Sayed Abeer M. 
Published: February 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
5‐(1H‐Benzimidazol‐1‐yl)‐3‐alkoxy‐2‐thiophenecarbonitriles as Potent, Selective, Inhibitors of IKK‐ε Kinase.
Authors: Bamborough Paul , Christopher John A. , Cutler Geoffrey J. , Dickson Marion C. , Mellor Geoffrey W. , Morey James V. , Patel Champa B. , Shewchuk Lisa M. 
Published: February 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Gold(I)‐Catalyzed Formation of 5‐Methylene‐1,3‐oxazolidin‐2‐ones.
Authors: Buzas Andrea , Gagosz Fabien 
Published: February 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Huisgen Reaction of Nitrile Oxides and Nitrile Imines Leading to Isoxazoline and Pyrazole‐4,6‐diones.
Authors: Kaur J. , Singh B. , Singal K. K. 
Published: February 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
A Study of the Scope and Regioselectivity of the Ruthenium‐Catalyzed [3 + 2]‐Cycloaddition of Azides with Internal Alkynes.
Authors: Majireck Max M. , Weinreb Steven M. 
Published: February 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Facile Synthesis of 3‐Carbamoyl‐1,2,4‐oxadiazoles.
Authors: Tamura Mina , Ise Yumiko , Okajima Yoshikazu , Nishiwaki Nagatoshi , Ariga Masahiro 
Published: February 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Highly Regioselective Catalytic Oxidative Coupling Reactions: Synthetic and Mechanistic Investigations.
Authors: Hull Kami L. , Lanni Erica L. , Sanford Melanie S. 
Published: February 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Intermediates in the Transformation of 1,2‐Dialkylpyrimidinium Iodides in the Kost—Sagitullin Rearrangement.
Authors: Danagulyan G. G. , Tadevosyan D. A. , Kinoyan F. S. 
Published: February 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Synthesis and Antibacterial Activity of Various Substituted s‐Triazines.
Authors: Srinivas K. , Srinivas U. , Bhanuprakash K. , Harakishore K. , Murthy U. S. N. , Rao V. Jayathirtha 
Published: February 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Synthesis of 4‐Aryl‐1,3‐diphenyl‐1,4,5,10‐tetrahydropyrazolo[3,4‐b] [1,5]benzodiazepines.
Authors: Dzvinchuk I. B. , Turov A. V. , Lozinskii M. O. 
Published: February 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Manganese(III) Acetate Promoted Regioselective Phosphonation of Heteroaryl Compounds.
Authors: Mu Xue‐Jun , Zou Jian‐Ping , Qian Qiu‐Feng , Zhang Wei 
Published: February 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Synthesis, NMR Spectroscopic Characterization and Reactions of 2,6‐Difluorophenylxenon Fluoride, 2,6‐F2C6H3XeF.
Authors: Bock Harald , Scherer Harald , Tyrra Wieland , Naumann Dieter 
Published: February 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Haemolytic Activity and Adjuvant Effect of Notoginsenoside K (I) from the Roots of Panax notoginseng.
Authors: Qin Feng , Ye Yi‐Ping , Sun Hong‐Xiang 
Published: February 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Kalanchosides A—C, New Cytotoxic Bufadienolides from the Aerial Parts of Kalanchoe gracilis.
Authors: Wu Pei‐Lin , Hsu Yu‐Lin , Wu Tian‐Shung , Bastow K. F. , Lee Kuo‐Hsiung 
Published: February 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
One‐Pot Synthesis of Chiral Dehydroproline Esters: [3 + 2]‐Type Cycloaddition Reaction of Allenylstannane and α‐Imino Ester.
Authors: Fuchibe Kohei , Hatemata Rina , Akiyama Takahiko 
Published: February 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Dialkylphosphates as Stereodirecting Protecting Groups in Oligosaccharide Synthesis.
Authors: Yamada Takeshi , Takemura Kazunobu , Yoshida Jun‐ichi , Yamago Shigeru 
Published: February 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Concise and Efficient Synthesis of Calothrixin B.
Authors: Sissouma Drissa , Maingot Lucie , Collet Sylvain , Guingant Andre 
Published: February 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Stereoselective Synthesis of 2′‐C‐Methyl‐cyclopropyl‐Fused Carbanucleosides as Potential anti‐HCV Agents.
Authors: Lee Jeong A. , Kim Hea Ok , Tosh Dilip K. , Moon Hyung Ryong , Kim Sanghee , Jeong Lak Shin 
Published: February 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Synthesis of Novel Dimeric Cationic Lipids Based on an Aromatic Backbone Between the Hydrocarbon Chains and Headgroup.
Authors: Paul Bishwajit , Bajaj Avinash , Indi S. S. , Bhattacharya Santanu 
Published: February 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Antiherpetic Flavones from the Heartwood of Artocarpus gomezianus.
Authors: Likhitwitayawuid Kittisak , Chaiwiriya Saowalak , Sritularak Boonchoo , Lipipun Vimolmas 
Published: February 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Genetic Algorithm‐Optimized QSPR Models for Bioavailability, Protein Binding, and Urinary Excretion.
Authors: Wang Junmei , Krudy George , Xie Xiang‐Qun , Wu Chengde , Holland George 
Published: February 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Single‐Crystalline CdSe Nanostructures: From Primary Grains to Oriented Nanowires.
Authors: Zhao Lili , Lu Tiezheng , Yosef Maekele , Steinhart Martin , Zacharias Margit , Goesele Ulrich , Schlecht Sabine 
Published: February 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
High‐Pressure/High‐Temperature Synthesis of Transition Metal Oxide Perovskites
Authors: Rodgers Jennifer A. , Williams Anthony J. , Attfield J. Paul 
Published: February 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Hetero‐Diels—Alder and Cheletropic Additions of Sulfur Dioxide to Conjugated Dienes. Experimental Facts and Theoretical Analysis
Authors: Vogel Pierre , Sordo Jose A. 
Published: February 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Asymmetrically Modified Nickel Catalyst for the Enantio‐Differentiating Hydrogenation of Prochiral Ketones
Authors: Osawa T. , Harada T. , Takayasu O. 
Published: February 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Selective Deoxygenation of Sugar Polyols to α,ω‐Diols and Other Oxygen Content Reduced Materials ‐ A New Challenge to Homogeneous Ionic Hydrogenation and Hydrogenolysis Catalysis
Authors: Schlaf Marcel 
Published: February 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Exploring the Catalytic Activity of a Noble Metal: The Ag Catalyzed Ethylene Epoxidation Reaction
Authors: Bocquet Marie‐Laure , Michaelides Angelos 
Published: February 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Investigation of Protein–Ligand Interactions by Mass Spectrometry
Authors: Sinz Andrea 
Published: February 2007

AbstractThe rate of drug discovery is greatly dependent on the development and improvement of rapid and reliable analytical methods that allow screening for protein–ligand interactions. The solution‐based methods for investigating protein–ligand interactions by mass spectrometry (MS), which are discussed in this paper, are hydrogen/deuterium exchange of protein backbone amide hydrogens, and photoaffinity labeling. Moreover, MS analysis of intact noncovalent protein–ligand complexes is described. Fourier transform ion cyclotron resonance mass spectrometry (FTICR–MS) with its ultra‐high resolution and excellent mass accuracy is also considered herein as it is gaining increasing popularity for a mass spectrometric investigation of protein–ligand interactions.
Physiological effects of separation and reunion in relation to attachment and temperament in young children
Authors: Oosterman Mirjam , Schuengel Carlo 
Published: February 2007

AbstractThis study examined physiological effects of separation and reunion in a sample 3‐ to 6‐year‐old children. Using continuous ambulatory recording, changes in heart rate (HR), respiratory sinus arrhythmia (RSA), and pre‐ejection period (PEP) were compared across the episodes of a separation–reunion procedure based on the strange situation. RSA decreased significantly over the course of the procedure as well as on separation from the parent and not the stranger, supporting that separation from the attachment figure elicited vagal withdrawal in young children. The absence of significant PEP effects suggest that the separation–reunion procedure, and more specifically separation from the parent, was not threatening enough to activate the sympathetic nervous system, even if children were insecure attached and inhibited with regard to strangers. Some of the variability in HR increases to reunion was explained by younger age. The findings highlight the role of the ANS as a regulatory process in the parent–child relationship. © 2007 Wiley Periodicals, Inc. Dev Psychobiol 49: 119–128, 2007.
T cell‐derived TNF down‐regulates acute airway response to endotoxin
Authors: Togbe Dieudonnée , Grivennikov Sergei I. , Noulin Nicolas , Couillin Isabelle , Maillet Isabelle , Jacobs Muazzam , Maret Marielle , Fick Lizette , Nedospasov Sergei A. , Quesniaux Valérie F. J. , Schnyder Bruno , Schnyder‐Candrian Silvia 
Published: February 2007

AbstractAcute and chronic airway inflammations caused by environmental agents including endotoxin represent an increasing health problem. Local TNF production may contribute to lung dysfunction and inflammation, although pulmonary neutrophil recruitment occurs in the absence of TNF. First, we demonstrate that membrane‐bound TNF is sufficient to mediate the inflammatory responses to lipopolysaccharide (LPS). Secondly, using cell type‐specific TNF‐deficient mice we show that TNF derived from either macrophage/neutrophil (M/N) or T lymphocytes have differential effects on LPS‐induced respiratory dysfunction (enhanced respiratory pause, Penh) and pulmonary neutrophil recruitment. While Penh, vascular leak, neutrophil recruitment, TNF, and thymus‐ and activation‐regulated chemokine/CCL17 (TARC) expression in the lung were reduced in M/N‐deficient mice, T cell‐specific TNF‐deficient mice displayed augmented Penh, vascular leak, neutrophil influx, increased CD11c+ cells and expression of TNF, TARC and murine CXC chemokines KC/CXCL1 in the lung. In conclusion, inactivation of TNF in either M/N or T cells has differential effects on LPS‐induced lung disease, suggesting that selective deletion of TNF in T cells may aggravate airway pathology.
CD83 expression on dendritic cells and T cells: Correlation with effective immune responses
Authors: Aerts‐Toegaert Cindy , Heirman Carlo , Tuyaerts Sandra , Corthals Jurgen , Aerts Joeri L. , Bonehill Aude , Thielemans Kris , Breckpot Karine 
Published: February 2007

AbstractHuman CD83 is a marker molecule for mature dendritic cells (DC) and is also expressed on activated B and T cells. Although CD83 has been implicated in immune responses, its function on DC and T cells remains unclear. In this study, we wanted to assess the role of CD83 expressed on DC and T cells in the immune response. Down‐regulation of CD83 expression on human DC through RNA interference (RNAi) results in a less potent induction of allogeneic T cell proliferation, reduced IFN‐γ secretion by established T cells and decreased capacity in the priming of functional tumor antigen‐specific CD8+ T lymphocytes. In addition, CD83 mRNA‐electroporated DC are stronger T cell stimulators. However, CD83 overexpression on Melan‐A/MART‐1‐specific tumor‐infiltrating lymphocytes (TIL) circumvents the need for CD83 expression on DC. Co‐culture of immature DC with TIL or K562 cells overexpressing CD83 results in the production of enhanced levels of pro‐inflammatory cytokines, whereas this production is less pronounced or even absent in co‐cultures with non‐modified TIL or K562 cells. In conclusion, we demonstrate that CD83 expression on T cells and DC modulates the immune response by activating DC and by delivering costimulatory signals for the stimulation of naive and memory T cells, respectively.
Palladium‐Catalyzed Buchwald–Hartwig Coupling of Deactivated Aminothiophenes with Substituted Halopyridines
Authors: Begouin Agathe , Hesse Stéphanie , Queiroz Maria‐João R. P. , Kirsch Gilbert 
Published: February 2007

AbstractThe palladium‐catalyzed Buchwald–Hartwig coupling of several deactivated aminothiophenecarboxylates with differently substituted halopyridines has been performed for the first time by using Pd(OAc)2, Xantphos as the ligand, and Cs2CO3 as the base. When 2,6‐dihalopyridines were used, the proportion of diaminated product increases with the reactivity of the halopyridines (iodo > bromo > chloro). A bromo monoaminated pyridine derivative, obtained by Buchwald–Hartwig coupling, was further used in the Suzuki coupling of aryl boronic acids bearing electron‐withdrawing or electron‐donating groups. These latter compounds are very interesting as they possess diheteroarylamine and heteroaryl–aryl skeletons including pyridine and thiophene moieties.(© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2007)
Gold Catalysis: Selectivity Problems in Hydroarylations with Pyrroles
Authors: Hashmi A. Stephen K. , Salathé Ralph , Frey Wolfgang 
Published: February 2007

AbstractGold‐catalyzed reactions of pyrrole derivatives with methyl vinyl ketone preferentially give rise to doubly substituted products, with an excess of methyl vinyl ketone even triple substitutions can be observed. This is independent of the electronic nature of substituents on the pyrrole ring, even substrates with electron‐withdrawing acyl substituents in 1‐, 2‐ or 3‐position show this behavior. The NH group of the pyrrole ring may be unprotected, no competing hydroamination is observed. In an intramolecular competition experiment with a furan ring only the pyrrole ring reacted. The constitutions of the highly‐substituted pyrroles were proven by NMR spectroscopy and one X‐ray structure analysis. Control experiments show that Yb(OTf)3 does not catalyze these reactions, but Ag+ and H+ does. Contrary to pyrroles, under similar reaction conditions indoles show a clean monosubstitution reaction. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2007)
Oxidative status of DBA/1J mice with type II collagen‐induced arthritis
Authors: Choi Eun‐Mi 
Published: February 2007

AbstractThe present study was undertaken to compare the oxidant statuses of mice with collagen‐induced arthritis (CIA) and those of healthy mice. For this purpose, serum oxidant products and arthritic profiles were measured in DBA/1J mice with CIA. In addition, the levels of oxidation products and the activities of antioxidant enzymes were determined in liver, heart, spleen, kidney, lung and brain. The induction of arthritis significantly increased anti‐collagen antibody, rheumatoid factor, interleukin (IL)‐1β, IL‐6, protein carbonyl (PCO), advanced glycation end‐products (AGE), malondialdehyde (MDA) and low density lipoprotein (LDL)‐cholesterol levels in serum (P < 0.05). CIA in DBA/1J mice was associated with significantly lower activities of superoxide dismutase, glutathione peroxidase and glutathione reductase in spleen but higher levels of oxidation products in spleen, kidney and liver than healthy normal mice (P < 0.05). However, lower concentrations of oxidized protein and higher activities of antioxidant enzymes were observed in CIA mouse lung and brain than in healthy normal mice. Dexamethasone treated CIA mice had decreased arthritis‐related indices and showed: reduced PCO and AGE in spleen and brain, and increased PCO and AGE in heart, kidney and lung; increased MDA in heart, spleen, lung and brain; reduced SOD and GR activities in lung and brain; increased GPx activity in spleen and brain; and increased GR activity heart and spleen. These data suggest that mice with CIA were more susceptible to oxidative damage in the spleen and liver under the chronic inflammatory conditions. Copyright © 2007 John Wiley & Sons, Ltd.
Pullulan‐based hydrogel for smooth muscle cell culture
Authors: Autissier Aude , Letourneur Didier , Le Visage Catherine 
Published: February 2007

AbstractA hydrogel was prepared from pullulan and evaluated as a novel biomaterial for vascular engineering. Using a crosslinking process with sodium trimetaphosphate in aqueous solution, homogeneous, transparent, and easy‐to‐handle pullulan gels were obtained with water‐content higher than 90%. A circular punch was used to cut 6‐mm diameter and 2‐mm thickness discs for cell culture. Environmental scanning electron microscopy analysis of hydrated gels revealed a smooth surface, on which rabbit vascular smooth muscle cells were successfully seeded. The absence of cytotoxicity was evidenced by a live/dead assay. Fluorescence‐labeled cells were observed adhering and progressively spreading out on the surface of the material. Cellular proliferation was followed for up to 1 week using an MTT assay. In addition, a complete in vitro degradation of the gels was achieved in 3 h upon incubation in a pullulanase solution (44 U/mL). In conclusion, we have shown the feasibility of preparing a biocompatible pullulan‐based hydrogel that could support vascular cell culture. Based on these promising results, future studies will focus on the seeding of vascular cells on tubular‐shaped hydrogels and the in vivo implantation of these new biomaterials. © 2007 Wiley Periodicals, Inc. J Biomed Mater Res, 2007