bluuebunny/crossref_metadata_2025_split huggingface dataset:
Integrating Phenotypic Information of Obstructive Sleep Apnea and Deep Representation of Sleep-Event Sequences for Cardiovascular Risk Prediction
Authors: Zheng Yali , Song Zhengbi , Cheng Bo , Peng Xiao , Huang Yu , Min Min 
Published: March 2024

Abstract
Background: Advances in mobile, wearable and machine learning (ML) technologies for gathering and analyzing long-term health data have opened up new possibilities for predicting and preventing cardiovascular diseases (CVDs). Meanwhile, the association between obstructive sleep apnea (OSA) and CV risk has been well-recognized. This study seeks to explore effective strategies of incorporating OSA phenotypic information and overnight physiological information for precise CV risk prediction in the general population.
Methods: 1,874 participants without a history of CVDs from the MESA dataset were included for the 5-year CV risk prediction. Four OSA phenotypes were first identified by the K-mean clustering based on static polysomnographic (PSG) features. Then several phenotype-agnostic and phenotype-specific ML models, along with deep learning (DL) models that integrate deep representations of overnight sleep-event feature sequences, were built for CV risk prediction. Finally, feature importance analysis was conducted by calculating SHapley Additive exPlanations (SHAP) values for all features across the four phenotypes to provide model interpretability.
Results: All ML models showed improved performance after incorporating the OSA phenotypic information. The DL model trained with the proposed phenotype-contrastive training strategy performed the best, achieving an area under the Receiver Operating Characteristic (ROC) curve of 0.877. Moreover, PSG and FOOD FREQUENCY features were recognized as significant CV risk factors across all phenotypes, with each phenotype emphasizing unique features.
Conclusion: Models that are aware of OSA phenotypes are preferred, and lifestyle factors should be a greater focus for precise CV prevention and risk management in the general population.
The effect of a split-dose intravenous dexamethasone and a single high-dose on postoperative blood glucose after total joint arthroplasty： A randomized double-blind placebo-controlled trial
Authors: Liu Xiao-yang , Mou Ping , Cao Jian , Chen Xu-ming , Wang Hao-yang , Zeng Wei-nan , Zhou Zong-ke 
Published: March 2024

Abstract

Background
In patients undergoing total joint arthroplasty (TJA), the administration of dexamethasone may contribute to perioperative blood glucose (BG) disturbances, potentially resulting in complications, even in patients without diabetes. This study aimed to demonstrate the impact of different administration regimens of dexamethasone in postoperative BG levels.
Methods
In this randomized, controlled, double-blind trial, 136 patients without diabetes scheduled for TJA were randomly assigned to three groups: two perioperative saline injections (Group A, placebo); a single preoperative injection of 20 mg dexamethasone and a postoperative saline injection (Group B), and two perioperative injections of 10 mg dexamethasone (Group C). Primary outcomes were the postoperative fasting blood glucose (FBG) levels. Secondary outcome parameters were the postoperative postprandial blood glucose (PBG) levels. Postoperative complications within 90 days were also recorded. Risk factors for FBG ≥ 140 mg/dl and PBG ≥ 180 mg/dl were investigated.
Results
Compared to Group A, there were transient increases in FBG and PBG on postoperative days (PODs) 0 and 1 in Groups B and C. Statistical differences in FBG and PBG among the three groups were nearly absent from POD 1 onward. Both dexamethasone regimens did not increase the risk for postoperative FBG ≥ 140 mg/dl or PBG ≥ 180 mg/dl. Elevated preoperative HbA1c levels may increase the risk of postoperative FBG ≥ 140 mg/dl or PBG ≥ 180 mg/dl, respectively.
Conclusion
Perioperative intravenous high-dose dexamethasone to patients without diabetes has transient effects on increasing BG levels after TJA. However, no differences were found between the split-dose and single high-dose regimens. The elevated preoperative HbA1c, but not the dexamethasone regimens were the risk factor for FBG ≥ 140 mg/dl and PBG ≥ 180 mg/dl.
Trial registration
Chinese Clinical Trail Registry, ChiCTR2300069473. Registered 17 March 2023, https://www.chictr.org.cn/showproj.html?proj=186760.
Bayesian Stochastic Frontier Models under the Skew Normal Settings
Authors: Wei Zheng , Choy S.T. Boris , Wang Tonghui , Zhu Xiaonan 
Published: March 2024

Abstract
Recently, a skew normal-based stochastic frontier model has emerged as a promising tool for efficiency analysis. In this paper, a Bayesian framework for statistical inference is presented, incorporating both informative and non-informative prior knowledge. The efficacy of the Bayesian approach is evaluated through rigorous examination using both simulation data and real data from a manufacturing productivity study. A comprehensive comparison with the conventional maximum likelihood approach is conducted. Results from both simulated and empirical investigations unequivocally demonstrate the superior performance of the Bayesian methodology.
Giant cell tumor of the bone: Both common and rare clinical aspects. Single institute experience
Authors: Mirioglu Akif , Dalkir Kaan Ali , Kiran Veli Can , Olke Hakki Can , Kundakci Bugra , Bagir Melih , Deveci Mehmet Ali , Ozkan Cenk 
Published: March 2024

Abstract

Objective Giant cell tumor of the bone remains one of the popular subjects for its biologically and clinically unpredictable behaviors. This paper presents the long-term outcomes, common and also rare clinical features of the patients with giant cell tumors of the bone.Methods Sixty-eight patients were included in the study between January 1996 and December 2022. Demographic data of the patients were extracted from the hospital database. The radiological assessment was conducted using the Picture Archive Communication System. Information on local adjuvants, filling material of the residual space, systemic administration of Denosumab, and presence of metastasis and local recurrences were enrolled from the patient files. The tumors were classified according to Campanacci classification.Results The most frequent site for the tumor was the knee (59.3%). Among the tumors 22.1% were grade-1, 39.7% were grade-2 and 38.2% were grade-3. The mean tumor volume was 182.8 cm3. Sixteen (23.5%) patients had received Denosumab as a systemic treatment. Fifty-five patients were treated with curettage, twelve with resection, and one with amputation. Chemical local adjuvants were used in 42 patients. The tumor bed was filled with cement in 38 patients, bone graft in 12, and remained unfilled in 5 patients. The rate of recurrence was 35.3%. Six patients experienced multiple recurrences. The rate of metastasis was 11.8%, and malignant giant cell tumor of the bone was diagnosed in two (2.9%) patients. Age, gender, tumor grade, size, and location, neo-adjuvant denosumab treatment, the use or type of local adjuvants, and the presence of tumor thrombus were not found to be related to recurrence or metastasis rates; however, marginal resection as initial surgery was found to be significantly related to decreased recurrence rates.Conclusion Metastasis and local recurrence rates were not affected by the preoperative Campanacci grade, neo-adjuvant denosumab administration, type of local adjuvant, filling material, or tumor volume. However, decreased recurrence rate was found to be related to the patients underwent resection.
Rigorous Quality Assessment of Clinical Practice Guidelines for Microfluidic Technologies as Rapid Tests during COVID-19 using the AGREE II Instrument
Authors: Shahid Hammad , Ramsay Kaitlyn 
Published: March 2024

Abstract
Microfluidic technologies offer a paradigm shift in healthcare diagnostics and monitoring, with potential implications across a multitude of clinical scenarios. Their optimal implementation hinges on robust, evidence-based clinical guidelines. This study provides an in-depth quality assessment of existing guidelines for microfluidic technologies used to rapidly diagnose COVID-19 utilizing the Appraisal of Guidelines for Research and Evaluation II (AGREE II) instrument.
Combined Lie’s type D and type A agenesis of the left internal carotid artery diagnosed by magnetic resonance angiography
Authors: Maki Takashi , Uchino Akira , Sugiyama Munehiro , Mizunuma Kimiyoshi , Baba Yasutaka 
Published: March 2024

Abstract

Purpose: To report a rare case of internal carotid artery (ICA) agenesis combined with Lie’s types D and A, diagnosed by magnetic resonance angiography (MRA).
Methods: A 60-year-old woman with dizziness underwent cranial magnetic resonance imaging (MRI) and MRA of the intracranial region for the evaluation of brain and vascular lesions. The magnetic resonance machine was a 3.0-T scanner.
Results: MRI showed no abnormalities, except for multiple small white matter lesions. MRA showed that the left ICA was absent, except for the supraclinoid segment, and an anastomotic vessel was present between the paraclinoid segments of the bilateral ICAs, suggesting Lie's type D ICA agenesis. The left posterior communicating artery (PCoA) was also present. Thus, there were also features of type A ICA agenesis. The anastomotic vessels between the bilateral ICAs and ipsilateral PCoA were relatively small in caliber.
Conclusion: Lie’s type D ICA agenesis usually does not communicate with the anterior and posterior circulations. We encountered a case of combined type D and type A ICA agenesis. To our knowledge, no similar case has been reported in the English literature. This is the second case of type D ICA agenesis with patent ipsilateral PCoA. In these two cases of patent ipsilateral PCoA, the anastomotic vessels between the bilateral ICAs were relatively small in caliber. ICA agenesis is an extremely rare abnormality, and most patients are asymptomatic. However, it can be associated with an increased risk of stroke and aneurysm formation.
A comparison of ductal stenting and surgical shunts for infants with duct-dependent pulmonary blood flow; the impact of single versus biventricular repair pathways on outcomes.
Authors: Fitzgerald Nicholas , Adams Paul , Mervis Jonathan , Webb Annabel , Roberts Philip , Ayer Julian 
Published: March 2024

Abstract

Background: Ductal stenting (DS) is an alternative to the Blalock-Taussig-Thomas Shunt (BTTS) as initial palliation for congenital heart disease with duct dependent pulmonary blood flow (DDBPF). We sought to analyse the impact of intended single ventricle (SV) and biventricular (BiV) repair pathways on the outcome of DS and BTTS in infants with DDPBF.
Methods: A single-centre, retrospective comparison of infants with DDPBF who underwent either DS (2012-2022) or BTTS procedures (2013-2017). Primary outcomes included all-cause mortality and risk of unplanned re-intervention. Participants were divided into four groups: 1.SV with DS, 2.SV with BTTS, 3.BiV with DS and 4.BiV with BTTS.
Results: Fifty-one DS (SV 45%) and 86 BTTS (SV 49%) procedures were undertaken. For those who had DS, mortality was lower in the BiV compared to SV patients (BiV: 0/28, versus SV: 4/23, P=0.04). Compared to BiV DS, BiV BTTS had a higher risk of combined death or unplanned re-intervention (HR 4.28; CI 1.25-14.60; p=0.02). In SV participants, there was no difference for either primary outcome based on procedure type. DS was associated with shorter intensive care length of stay for SV participants (mean difference 5 days, P=0.01) and shorter intensive care and hospital stay for BiV participants (mean difference 11 days for both outcomes, P=0.001).
Conclusions:
There is a survival benefit for DS in BiV participants compared with DS in SV and BTTS in BiV participants. Ductal stenting is associated with a shorter intensive care and hospital length of stay.
Two flavors in adulterated sesame oil: Discovery, Confirmation, and Content Regularity Study
Authors: Liu chuan , Chen Yan-Qiu , Lin Hao , Shi Pei-Yu , Wu Wen-Lin , Xiao Quan-Wei , Dai Qin 
Published: March 2024

Abstract

Gas chromatography-mass spectrometry (GC-MS) was utilized to identify the 5-(2-hydroxyethyl)-4-methylthiazole and γ-Nonanolactone in adulterated sesame oil. Liquid chromatography-tandem mass spectrometry (LC-MS/MS) was then employed for qualitative analysis of these flavors. A quantitative analysis method was successfully developed using methanol extraction and vanillin-D3 as an internal standard, with analyte recoveries ranging from 88.5–102.2% and relative standard deviations between 2.6% and 10.5% (n = 6). Subsequently, 31 batches of sesame oil from the market were tested, revealing that all samples contained the identified flavors within a relatively consistent range. However, some samples exhibited unusually high concentrations of these flavors, suggesting a potential risk of adulteration.
Phosphoproteomics Analysis of Elderly people with sarcopenia
Authors: 尤 聪瑶 , Zhao Yi-ding , Yang Tie-ying , Zhang Yan 
Published: March 2024

Abstract
Sarcopenia is a progressive and systemic skeletal muscle disease that involves an accelerated loss of muscle mass and function. It is associated with increased adverse outcomes, including falls, functional decline, frailty, and death. With the advent of an aging society, sarcopenia has become a focus of intensive research. However, the molecular signaling pathways and phosphosignaling transduction changes in patients with sarcopenia are still unclear. To this end, we performed a quantitative mass spectrometry-based phosphoproteomics study on 6 patients with sarcopenia and 6 normal elderly subjects, and quantitatively analyzed 6163 phosphorylation sites of 2253 proteins. Gene Ontology (GO) functional enrichment and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analysis showed that many phosphorylated proteins are involved in sarcomere organization and muscle filament sliding pathways. Kinase prediction analysis suggests that serine/threonine protein kinases VRK1, VRK2, etc. may play an important role in abnormal muscle metabolism. This study greatly expands our understanding of this disease by performing phosphoproteomics analysis on patients with sarcopenia. These findings provide a basis for the study of other age-related diseases.
Carbon sequestration in sugarcane plant - soil system as influenced by nutrient integration practices under Indo-Gangetic plains of India
Authors: Kumar Ajeet , Meena Sunita Kumari , Singh Sanjay Kumar , Sinha S.K. , Singh A.K. 
Published: March 2024

Abstract

Sugarcane is a multi-purpose crop. The capability of sugarcane crop to sequestrate carbon into soil and plant is of great importance. Under this study the carbon sequestration in planted sugarcane and their rhizospheric soil under different nutrient management practices was assessed. As IPCC reported, that the rising temperature of earth surface resulted of GHGs emission which causes global warming. In order to stabilize the global temperature, the anthropogenic CO2has to be mitigated to a significant level and the surplus atmospheric CO2in plants and soil has to be sunk, under this circumstance, sugarcane cultivation plays pivotal role in utilising CO2since it is a C4plant having high efficiency of utilising CO2during photosynthesis. There is another intervention might be enhancing the CO2capture by changing the nutrient management practices which enhances chlorophyll synthesis by the way of increasing nitrogen efficiency in sugarcane. The different treatment composition enhances photosynthesis where more CO2has been captured. Thus the sugarcane crop and rhizospheric soils act as important carbon sinks in decarbonisation of atmosphere that ultimately reduces carbon level and causes the global cooling.Soil Properties and Carbon Storage: The results showed that soil physical properties and chemical properties were significantly differed among treatments due to application of different organic amendments over control. Soil organic carbon (SOC) was analysed which ranges from 0.47 to 0.67%. The different organic amendments treatments had a considerable effect on soil bulk density and porosity with significant improvement in soil carbon storage.Plant Carbon Storage: The carbon stocks in different sugarcane plant parts, including roots, shoots and leaves were significantly different. The highest amount of carbon stock was found in leaves (877.08 kg ha− 1) under T6followed by roots (668.74 kg ha− 1) in T2and carbon stock in shoots (422.77 kg ha− 1) in T5showing that 30.41% and 107.58% more carbons were stored in the leaves as compared to the roots and shoots while in roots 58.18% more carbon stored in comparison to shoots. The total carbon storage in sugarcane biomass including aboveground parts and belowground part i.e. roots, in different treatment was significantly different. The mean value of carbon stored in the aboveground parts (leaves and stalks) was significantly higher (1239.65 kg ha− 1) than that of underground plant part (621.73 kg ha− 1) (roots). The results showed that the sugarcane farming practices have promising effect for carbon sequestration and consequently enhancing the mitigation of climate change impacts.
Appliances Energy Prediction using Supervised Machine Learning Approach
Authors: Beldar Pankaj Ramanlal 
Published: March 2024

Abstract
This paper presents and discusses data-driven predictive models for the energy use of appliances. Data used include measurements of temperature and humidity sensors from a wireless network, weather from a nearby airport station and recorded energy use of lighting fixtures. The paper discusses data filtering to remove non-predictive parameters and feature ranking. When using all the predictors. From the wireless network, the data from the kitchen, laundry and living room were ranked the highest in importance for the energy prediction. The prediction models with only the weather data, selected the atmospheric pressure (which is correlated to wind speed) as the most relevant weather data variable in the prediction. Therefore, atmospheric pressure may be important to include in energy prediction models and for building performance modelling.
Global climate change effect on Asian Mus musculus; Implication from last glacial maximum to the end of the 21st century
Authors: Afzali Yaser Amir 
Published: March 2024

Abstract
Global climate change poses unprecedented challenges to biodiversity, prompting urgent investigations into its effects on various species. This study focuses on Mus musculus, a small rodent species and a crucial indicator of ecosystem health. Spanning from the last glacial maximum to the end of the 21st century, employed Species Distribution Models (SDMs) to assess the impacts of climate change on Mus musculus and its four subspecies across Asia (M. m musculus, M. m domesticus, M. m castaneus, and M. m bactrianus). The SDMs reveal nuanced responses among subspecies, with M. m. domesticus, M. m. musculus, and M. m. castaneus facing potential habitat contractions, while M. m. bactrianus shows habitat expansion. Variable importance analysis highlights the significance of temperature-related variables, indicating the growing impact of rising temperatures on distribution patterns. Findings underscore the ecological implications of these shifts, emphasizing the need for tailored conservation strategies. The robustness of models, as indicated by high Area Under the Curve (AUC) values, enhances confidence in the reliability of predictions. Despite data limitations, this study contributes valuable insights into the complex dynamics between climate change and Mus musculus populations, guiding future conservation efforts in the face of ongoing global environmental transformations.
FACTORS AFFECTING CONSUMERS’ IMPULSE BUYING BEHAVIOUR FOR APPARELS:
Authors: Surabhi Agrawal  , Dr. Avinash Singh  
Published: March 2024

Impulse buying behaviour is a significant factor as marketers try to tap this behavior of customers to boost sales. The aim of this research is to explore the factors that have an influence on consumers’ impulse buying behaviour for apparels. A self administered questionnaire developed from the literature was administered to 109 consumers. Data have been analysed by using SPSS 22 for correlation and regression. The resulted values for the construct store environment, sales promotion and person’s situation, show positive significant influences with impulse buying, whereas the construct product qualities and shopping enjoyment tendency have an adverse effect on impulse purchase. The study provides merchants, academics, and scholars with helpful knowledge into the impulse buying behavior of Indian buyers, as well as the implications for the management of retailers. This study was restricted to Uttar Pradesh customers and apparel just.
DEVELOPMENT OF GRADE LEVEL ASSESSMENT TOOL IN SOCIAL SCIENCE (GLAT-SS) FOR GRADE VII &VIII BASED ON KARNATAKA STATE EDUCATION BOARD FOR TYPICALLY DEVELOPING CHILDREN AND CHILDREN WITH HEARING IMPAIRMENT
Authors: Dr. Alok Kumar Upadhyay  , Mr. Raj Kumar R.  , Ms. Sowmya N. S.  , Mr. Deepak Kumar  
Published: March 2024

The aim of the present study was to develop the Grade Level Assessment Tool in Social Science (GLAT-SS) for the Karnataka State Education Board's grades VII and VIII employing a survey design. The study's target population consisted of 29 schools spread across five districts in Karnataka. Purposive sampling technique was employed to select participants for the study.In the study, a total 866 typically developing children from five districts (Mysore, Chamarajnagar, Mandya, Bengaluru & Kalaburagi) of Karnataka State participated. For the pilot study, 100 typically developing children participated and 766 typically developing children studying in Grade VII & VIII from five districts of Karnataka State participated in the final data collection, among them 263 students (154 English and 109 Kannada) were from Mysuru district; 82 students (English medium) were from Chamrajnagara district; 12 students (English medium) from Mandya district; and 32 students (25 English and 07 Kannada) were from Bengaluru district participated.
The final analysis and interpretations of results reveal that There is significant difference found in performance of Grade Level Assessment Test (GLAT-SS) in Social Science between Typically Developing students and students with Hearing Impairment grade VII & VIII students studying in English Medium as well as Kannada Medium.
ROLE OF STUDENTS' AND TEACHERS' ASSOCIATIONS OF GAUHATI UNIVERSITY IN GOVERNANCE
Authors: Dr. Marie Kalita  
Published: March 2024

This paper focuses on Students' and Teachers' Associations of Gauhati University and their problems, democratic agitations, demands, fulfillments etc. in the greater interests of students and teachers. Since its establishment in January, 1948, Gauhati University, considered to be the mother university of the entire North East has been serving as a seat of Higher Education for this region till the late 80s. There are lots of problems due to the changing scenario of our country in political and economic affairs and also due to liberalization, globalization and privatization which needs to be addressed. Gauhati University has also borne the brunt of such impacts.
An attempt has been made in this paper to find out the demands of the students' and teachers' Associations of Gauhati University and also to see how they are acting as pressure groups for the fulfillment of their just demands. A descriptive survey method has been adopted and data collected by first hand studies by conducting interviews with the office bearers of these associations and also the authorities for the fulfillment of their just demands.