bluuebunny/crossref_metadata_2025_split huggingface dataset:
Flow intermittence prediction using a hybrid hydrological modelling approach: influence of observed intermittence data on the training of a random forest model
Authors: Mimeau Louise , Künne Annika , Branger Flora , Kralisch Sven , Devers Alexandre , Vidal Jean-Philippe 
Published: February 2024

Abstract. Rivers are rich in biodiversity and act as ecological corridors for plant and animal species. With climate change and increasing anthropogenic water demand, more frequent and prolonged periods of drying in river systems are expected, endangering biodiversity and river ecosystems. However, understanding and predicting the hydrological mechanisms that control periodic drying and rewetting in rivers is challenging due to a lack of studies and hydrological observations, particularly in non-perennial rivers. Within the framework of the Horizon 2020 DRYvER (Drying River Networks and Climate Change) project, a hydrological modelling study of flow intermittence in rivers is being carried out in three European catchments (Spain, Finland, France) characterised by different climate, geology, and anthropogenic use. The objective of this study is to represent the spatio-temporal dynamics of flow intermittence at the reach level in mesoscale river networks (between 120 and 350 km2). The daily and spatially distributed flow condition (flowing or dry) is predicted using the J2000 distributed hydrological model coupled with a random forest classification model. Observed flow condition data from different sources (water level measurements, photo traps, citizen science applications) are used to build the predictive model. This study aims to evaluate the impact of the observed flow condition dataset (sample size, spatial and temporal representativity) on the performance of the predictive model. Results show that the hybrid modelling approach developed in this study allows the spatio-temporal patterns of drying to be accurately predicted in the three catchments, with a sensitivity criterion above 0.9 for the prediction of dry events in the Finnish and French case studies and 0.65 in the Spanish case study. This study shows the value of combining different data sources of observed flow condition to reduce the uncertainty in predicting flow intermittence.
Do one-stage indications predict success following two-stage arthroplasty for chronic periprosthetic joint infection?
Authors: Kheir Michael M. , Anderson Christopher G. , Chiu Yu-Fen , Carli Alberto V. 
Published: February 2024

Abstract. Introduction: The 2018 International Consensus Meeting (ICM) proposed criteria for one-stage exchange arthroplasty in treating periprosthetic joint infection (PJI). Our study aimed to determine what proportion of PJI patients met the 2018 ICM criteria and how this affected infection-free survivorship for patients. Methods: All chronic PJI patients treated with two-stage exchange within our institution between 2017–2020 were retrospectively reviewed. Included cases met 2011 Musculoskeletal Infection Society (MSIS) criteria for PJI and had a 2-year minimum follow-up. Treatment success was defined as Tier 1A in the 2019 MSIS working group definition. ICM one-stage criteria included non-immunocompromised host, absence of sepsis, adequate soft tissue for closure, known preoperative pathogen, and susceptibility. Immunocompromised host was analyzed as two separate definitions. Kaplan–Meier survivorship, Cox regression, and univariate analyses were performed. Results: A total of 293 chronic PJI patients were included. Overall, treatment failure occurred in 64/293 (21.8 %) patients. Only 13 % (n=37) met ICM criteria definition no. 1 for one-stage exchange; 12 % (n=33) met definition no. 2. In both definitions, infection-free survivorship at 2 years did not differ between patients who met and did not meet criteria (p>0.05). Cox proportional hazard regression analyses demonstrated that the only variable predicting treatment failure was knee joint involvement (p=0.01). Conclusions: We found that a very limited number of chronic PJI patients were suitable for a one-stage exchange. Furthermore, the supposition that healthier hosts with known pathogens (the basis of the ICM criteria) yield better PJI treatment outcomes was not observed. These results justify the ongoing multicenter randomized control trial comparing one-stage versus two-stage treatment for chronic PJI.
A novel framework to investigate wind-driven snow redistribution over an Alpine glacier: combination of high-resolution terrestrial laser scans and large-eddy simulations
Authors: Voordendag Annelies , Goger Brigitta , Prinz Rainer , Sauter Tobias , Mölg Thomas , Saigger Manuel , Kaser Georg 
Published: February 2024

Abstract. Wind-driven snow redistribution affects the glacier mass balance by eroding or depositing mass from or to different parts of the glacier’s surface. High-resolution observations are used to test the ability of large-eddy simulations as a tool for distributed mass balance modeling. We present a case study of observed and simulated snow redistribution over Hintereisferner glacier (Ötztal Alps, Austria) between 6 and 9 February 2021. Observations consist of three high-resolution digital elevation models (Δx=1 m) derived from terrestrial laser scans taken shortly before, directly after, and 15 h after snowfall. The scans are complemented by datasets from three on-site weather stations. After the snowfall event, we observed a snowpack decrease of 0.08 m on average over the glacier. The decrease in the snow depth can be attributed to post-snowfall compaction and the wind-driven redistribution of snow. Simulations were performed with the Weather Research and Forecasting (WRF) model at Δx=48 m with a newly implemented snow drift module. The spatial patterns of the simulated snow redistribution agree well with the observed generalized patterns. Snow redistribution contributed −0.026 m to the surface elevation decrease over the glacier surface on 8 February, resulting in a mass loss of −3.9 kg m−2, which is on the same order of magnitude as the observations. With the single case study we cannot yet extrapolate the impact of post-snowfall events on the seasonal glacier mass balance, but the study shows that the snow drift module in WRF is a powerful tool to improve knowledge on wind-driven snow redistribution patterns over glaciers.
STRATEGI CONSUMER PROMOTION PT. SURYA MADISTRINDO (SUBSIDIARY OF PT. GUDANG GARAM, TBK) AREA OFFICE PURWOKERTO DI MASA PASCA PANDEMI COVID 1
Authors: Maria Consulata Wening  , Wiwik Novianti  , Mite Setiansah  
Published: February 2024

Di tengah situasi pandemi Covid 19, pemerintah membuat kebijakan yang mengharuskan masyarakat untuk melakukan kegiatannya di rumah dan menjaga jarak sosial. Sekalipun saat ini situasi Covid memasuki masa transisi dari pandemi ke endemi, hal ini mengakibatkan penurunan di beberapa sektor usaha, salah satu yang terdampak adalah PT. Surya Madistrindo. Tujuan penulisan jurnal ini adalah untuk mendeskripsikan langkah strategi yang dilakukan PT. Surya Madistrindo Area Office Purwokerto dalam melakukan consumer promotion sehingga produk Gudang Garam akan tetap dikenal & dikonsumsi oleh khalayak berdasar segmentasinya. Penelitian ini menggunakan metode penelitian studi kasus dengan pendekatan secara kualitatif. Ada beberapa langkah strategi yang dilakukan oleh PT Surya Madistrindo dalam melakukan consumer promotion, yang pertama adalah mengadakan bakti sosial dengan melibatkan komunitas. Yang kedua adalah penempatan unit promosi Gudang Garam, lalu yang ketiga adalah menambah alokasi pengadaan Media Luar Ruang (Outdoor), Yang keempat adalah menambah outlet investasi (Gudang Garam Strategic Partnership) dengan branding Gudang Garam di beberapa outlet retail, modern market serta di Horecatainment. Kemudian strategi yang terakhir adalah dengan memanfaatkan media sosial
PERAN MEDIA SOSIAL INSTAGRAM @GREENPEACEID SEBAGAI MEDIA KAMPANYE DALAM MENJAGA LINGKUNGAN
Authors: Fadli Ajril , Sazali Hasan 
Published: February 2024

Keberlangsungan hidup manusia bergantung pada lingkungan. Namun, kurangnya kesadaran manusia dalam menjaga lingkungan, menyebabkan banyak kerusakan terjadi. Untuk menumbuhkan kesadaran manusia, Greenpeace menggunakan instagram dalam memberikan informasi serta himbauan kepada manusia agar melestarikan lingkungan. Tujuan penelitian ini untuk menganalisis peran instagram sebagai media kampanye dengan mengkaji konten akun @greenpeaceid dan respon yang terjadi didalamnya. Peneliti menggunakan metode penelitian deskriptif kualitatif yang pelaksanaannya dilakukan dengan cara memantau dan menganalisis secara menyeluruh terhadap akun @greenpeaceid. Hasil dari penelitian ini adalah media sosial instagram @greenpeaceid sebagai media kampanye dalam menjaga lingkungan dinilai mempunyai peran yang penting karena mampu memberikan advokasi informasi mengenai lingkungan dan ada dampak positif yang hadir yakni dapat dilihat dari banyaknya respon positif baik dari jumlah likes maupun komentar yang baik dalam kesadaran menjaga lingkungan
Hookworm Anthelmintic Resistance: Novel Fecal Polymerase Chain Reaction Ancylostoma caninum Benzimidazole Resistance Marker Detection in a Dog
Authors: Evason Michelle , DeBess Emilio , Culwell Nicole , Ogeer Jennifer , Leutenegger Christian 
Published: February 2024

ABSTRACT
A 4 yr old castrated male greyhound presented with a history of chronic (&gt;3 wk) intermittent diarrhea. Initial fecal analysis identified infection with Ancylostoma caninum. Despite treatment with routine anthelmintics, the dog remained persistently A caninum positive for several months. A novel fecal gastrointestinal real-time polymerase chain reaction (qPCR) parasite panel detected A caninum and the genetic benzimidazole (BZ) F167Y resistance marker in multiple samplings over 48 hr. This finding, together with the dog’s clinical signs (diarrhea) and lack of response to routine anthelmintics, prompted treatment with cyclooctadepsipeptide emodepside, a drug currently not registered for dogs in the United States. The dog’s clinical signs resolved and post-treatment fecal qPCR testing was negative. However, 5 mo later, retesting with fecal qPCR detected A caninum and concurrent BZ resistance marker, as well as Giardia. A presumptive diagnosis of re-infection was made and the emodepside treatment was continued. The dog again reverted to undetected (A caninum and the 167 resistance marker) on reassessment fecal qPCR. This case report describes the use of a novel fecal qPCR panel for gastrointestinal parasites, persistent hookworm and BZ F167Y resistance marker detection in a dog, and highlights the importance of a stepwise approach to clinical management, treatment, and retesting.
Delayed Life-Threatening Hemorrhage Caused by Cranial Tibial Artery Pseudoaneurysm in Two Dogs
Authors: Grand Jean-Guillaume 
Published: February 2024

ABSTRACT
Two adult dogs were presented at 25 and 30 days following tibial external skeletal fixator placement (case 1) and tibial plateau leveling osteotomy (case 2), respectively. Clinical signs at presentation for each of them included acute onset lethargy, non–weight-bearing lameness, and hemorrhage at the surgical site with large hematoma formation. On admission, emergency whole blood transfusion was required in case 2 with a preoperative packed cell volume of 13%. Both dogs were diagnosed with pseudoaneurysm of the cranial tibial artery based on color Doppler ultrasonography. Additionally, computed tomography angiography was performed in one dog. Surgical treatment of the dogs included ligation of the cranial tibial artery supplying the pseudoaneurysm and curettage of hematoma. The surgery was completed without complications in case 1, but case 2 experienced inadvertent rupture of pseudoaneurysm with significant blood loss, which required another whole blood transfusion during the procedure. Both dogs had excellent functional recovery with no recurrence of clinical signs. We hypothesized that pseudoaneurysms were primarily caused by trauma secondary to placement of surgical implants or osteotomy. For orthopedic surgeons, it is important to recognize clinical signs of a potential tibial arterial pseudoaneurysm, as early surgical intervention may prevent loss of limb or life.
‘I Have Been Faithful to Thee, Cynara’: Parodying Canonical Pro-Slavery Novel in The Wind Done Gone
Authors: Rasiah Rasiah , Wantasen Isnawati Lydia , Tulung Golda Juliet , Rauf Ramis , Bilu La , Sofian Nur Israfyan 
Published: February 2024

Parody, as a specific case of adaptation and intertextuality, is not only burlesquing background text but also creating a critical distance through superimposition strategies. This paper sought to show the parodic means performed in the novel The Wind Done Gone (TWDG) written by Alice Randall. It was meant to be a parody of Margaret Mitchell's novel Gone with the Wind (GWTW) and has intertextuality with other literary works. The interconnection of the novel's narrative strategies and its effort to attach historical reassessment suggested a trustworthy reality of the black slave experience. Randall effectively deconstructed and reconstructed the black experience and identity, as well as dismantled the racist representation in the canonical novel GWTW. Enslaved black people are transformed into dominants as active agents and intelligent, creating a beautiful mulatto, tagging black intellectuals in American history and the new Negroes, naming ties, and providing verbatim quotes to revisit the stereotype and cultural misconstruction against black Americans. Randall seemed not to alter the meta-history of slavery but rather to show the irony of the racist discourse in the canonical saga and other popular media.
Sosialisasi Penyelesaian Masalah Klaim Penanganan Medical Logistik (Vaksin) melalui Ground Handling Bandara Soekarno Hatta
Authors: Lesmini Lis , Rizaldy Wynd , Firdaus Muhammad Iqbal 
Published: February 2024

The purpose of this activity is to provide socialization of problem solving of claiming medical logistics (Vaccine) handling to companies that handle medical logistics (vaccines) where most of the vaccines are included in the S oekarno Hatta ground handling warehousing, so that they can have human resources who understand and understand about handling medical logistics (vaccine) damage claims in accordance with the Regulations handling of international Air Transport Association (IATA) claims regarding Temperature Control Regulation and also The Air Cargo Tariff, so as to improve services to customers and assist government programs in overcoming the Covid 19 Pandemic. The activity was held on March 2, 2022 in Tangerang. Themethod used is socialization through online and offline with materialmapping, question and answer and video playback. Participants 13 people consisting of employees of various companies that handle medical logistics (vaccines) at Soekarno Hatta Airport, based on the results of the pre-survey and post survey given to participants, it shows an increase in participants' understanding and knowledge by 62.4% related to procedures for handling damage claims medical logistics (vaccines) and a good response of 61.54% from the participants that this socialization is useful and can be directly applied to their work and meet the target of achieving the PKM plan. This activity has been published through the Youtube channel so that it can be seen and studied by the wider community.
Uji Aktivitas Antihiperurisemia Ekstrak Terpurifikasi Rebung (Schizostachyum brachycladum KURZ) Pada Mencit (Mus musculus)
Authors: Hasan Tri Nuzul Aziza , Hadju Lodes , Himaniarwati  , Trisnaputri Dian Rahmaniar 
Published: February 2024

Hiperurisemia merupakan kondisi lebihnya kadar asam urat dalam darah. Untuk mengatasi hal tersebut biasanya dilakukan dengan menggunakan obat-obat sintetik. Namun alternatif lan yang bisa digunakan adalah dengan menggunakan obat dari bahan yang dinilai aman dan terbebas dari efek samping yang merugikan salah satunya yaitu rebung. Penelitian ini bertujuan untuk mengetahui aktivitas ekstrak terpurifikasi rebung (Schizostachyum brachycladum KURZ) terhadap penurunan kadar asam urat darah mencit (Mus musculus L.). Penelitian ini merupakan penelitian eksperimen. Sampel yang digunakan adalah rebung yang diekstraksi menggunakan metode maserasi dengan pelarut etanol 96% dan dilanjutkan dengan purifikasi ekstrak untuk memperoleh ekstrak yang murni dengan golongan senyawa yang diinginkan. Pengujian antihiperurisemia pada hewan uji dibagi menjadi 6 kelompok yaitu kelompok normal, kelompok kontrol negatif (Suspensi NaCMC), kelompok kontrol positif (Allopurinol), kelompok ekstrak terpurifikasi dosis 25 mg/kgBB, kelompok ekstrak terpurifikasi dosis 50 mg/kgBB, dan kelompok ekstrak terpurifikasi dosis 100 mg/kgBB. Evaluasi aktivitas antihiperurisemia ekstrak terpurifikasi rebung, pada semua kelompok hewan uji diinjeksikan jus hati ayam sebagai penginduksi asam urat. Analisis data dilakukan dengan menggunakan One-way Analysis of Variance (ANOVA) dan dilanjutkan dengan uji post-hoc LSD. Hasil uji hiperurisemia terhadap mencit yang diinduksikan jus hati ayam menunjukan bahwa ekstrak terpurifikasi rebung (Schizostachyum brachycladum KURZ) secara signifikan mampu menurunkan kadar asam urat darah dibandingkan kontrol negatif (p<0,05) dan hasilnya tidak jauh berbeda dengan kelompok kontrol positif (p>0,05). Penelitian ini dapat disimpulkan bahwa ekstrak terpurifikasi rebung (Schizostachyum brachycladum KURZ) memiliki aktivitas antihiperurisemia dengan dosis efektif 100 mg/kgBB.
Studi In Silico Senyawa Dari Saffron (Crocus sativus L.) Terhadap Reseptor Glikogen Sintase Kinase-3 Beta (GSK-3β) Sebagai Antidiabetes
Authors: Afriana Dian , Dewi Citra 
Published: February 2024

Saffron (Crocus sativus L.) merupakan tanaman dari genus iridaceae yang memiliki kandungan senyawa flavonoid, terpenoid, serta karotenoid yang diketahui berpotensi untuk menjadi kandidat antidiabetes. Dalam hal ini Glikogen Sintase Kinase-3 Beta (GSK-3β) merupakan protein kinase yang mempengaruhi jalur pensinyalan insulin sehingga menyebabkan resistensi insulin. Tujuan penelitian ini ialah untuk mengetahui interaksi molekuler senyawa dari saffron terhadap reseptor GSK-3β sebagai antidiabetes. Metode penelitian yang digunakan yaitu in silico melalui penambatan molekul (molecular docking) pada reseptor GSK-3β dengan kode PDB: 4PTE dan senyawa dari saffron dengan menggunakan software Autodock vina dan visualisasi menggunakan BIOVIA discovery studio 2019. Hasil yang diperoleh terdapat 9 senyawa yang memiliki afinitas lebih baik dari ligan alami dimulai dari rentang nilai -9 kkal/mol sampai -11,5 kkal/mol. dan didukung dengan kemiripan interaksi asam amino ≥50% dengan senyawa terbaik yaitu kaempferol-7-O-glucosidem memiliki kemiripan interaksi dengan ligan alami sebesar 85%. Hal ini menunjukkan bahwa senyawa dari saffron dapat menjadi kandidat obat antidiabetes
Formulasi dan Uji Aktivitas Masker Gel Peel-Off Ekstrak Etanol Bunga Asoka (Ixora coccinea L.) sebagai Antioksidan
Authors: Anandha kifli Shofiyyah , Dewi Citra , Pusmarani Jastria 
Published: February 2024

Penuaan kulit adalah proses biologis kompleks yang dipengaruhi oleh kombinasi endogen atau intrinsik (genetika, metabolisme seluler, hormon, dan proses metabolik) dan faktor ekstrinsik (faktor cahaya matahari kronis, polusi, radiasi pengion, kimiawi dan toksin). Ekstrak etanol bunga asoka (Ixora coccinea L.) memiliki kandungan senyawa metabolit sekunder alkaloid, fenol, flavonoid, steroid, dan saponin. Penelitian ini bertujuan untuk mengetahui karakteristik fisik formula dengan beberapa variasi konsentrasi sediaan masker gel peel-off dan aktivitas antioksidan ekstrak etanol bunga asoka (Ixora coccinea L.). Pengujian dibuat dalam empat formula gel peel-off dengan variasi konsentrasi zat aktif ekstrak etanol bunga asoka (Ixora coccinea L.) yang digunakan yaitu formula 0 (blanko), formula I (5%) dan formula II (10%) dan Formula III (15%). Pengolahan data menggunakan microsoft excel dan hasil penelitian antioksidan menggunakan rumus persamaan regresi linear sederhana. Formulasi sediaan gel peel-off ekstrak etanol bunga asoka (Ixora coccinea L.) telah memenuhi standar karakteristik fisik yang dilihat dari warna, bau, bentuk, homogenitas, viskositas, waktu mengering, nilai pH dan daya sebar. Pada formula 0 (blanko) memiliki aktivitas antioksidan lemah dengan nilai IC50 179,60 µg/mL, kemudian formula I (5%) dan formula II (10%) tidak terdapat aktivitas antioksidan berturut-turut memiliki nilai IC50 489,59 µg/mL, 300,99 µg/mL, aktivitas antioksidan ditunjukan pada formula III (15%) dengan nilai IC50 150,12 µg/mL (kategori sedang).
Francis Type Turbine Runner Design and Comparison with Model Test Results
Authors: Yılmaz Buğra , SÖZEN Adnan , Bendeş Oğuzhan 
Published: February 2024

Cavitation wear and hydraulic efficiency decrease in hydroelectric power plants have frequently been the subject of various research and studies. A hydroelectric power plant built on the Kızılırmak River in Türkiye started operating in 1960 and has not been subjected to any large-scale rehabilitation work other than general maintenance until today. The power plant has 4 Francis-type turbines, each with a power of 32 MW. Due to cavitation wear of turbine runners over the years, performance loss, vibration, and noise problems have arisen. Moreover, the maximum turbine hydraulic efficiency, which was 92% in 1960, the year the power plant was commissioned, decreased to 87.9% according to the efficiency measurements carried out at the power plant in 2020. In this study, Computational Fluid Dynamics (CFD) analyses were accomplished with Reynolds averaged Navier Stokes (RANS) calculations for the redesign of the Francis-type turbine runner and finally checked by a model test according to IEC 60193. It was observed that the model test and CFD results were close to each other, especially at the best efficiency point. The maximum turbine hydraulic efficiency, which was calculated as 94.95% as a result of CFD analysis at the nominal head, was calculated as 95.19% by the model test. The x-blade shape created in the redesigned turbine runner blades ensured homogeneous pressure distribution and increased the hydraulic efficiency significantly.
Canciones infantiles para el desarrollo de la lateralidad en la inteligencia espacial
Authors: Córdova Gallo Joselyn Dayana , Mendoza Casa Verónica Belén , Defáz Gallardo Yolanda Paola , Bravo Zambonino José María 
Published: February 2024

Introducción: La lateralidad es una parte importante del desarrollo humano que implica la capacidad de reconocer y utilizar el lado dominante del cuerpo para realizar tareas básicas.
Objetivo: Proponer un cancionero infantil como estrategia de enseñanza para el fortalecimiento de la lateralidad en la inteligencia espacial
Métodos: El presente estudio se desarrolló bajo la modalidad de proyecto factible, para lo cual se contemplaron las partes propuesta pro Dubs (2002) título, contexto, objetivos, justificación, marco referencial, metodología, diagnóstico o evaluación de necesidades, formulación de la propuesta, análisis de factibilidad o viabilidad y recomendaciones. Para la recolección de la información se trabajó con revisión documental, entrevista y observación. El contexto de estudio fueron las Unidades Educativas con el nivel de Educación Inicial de la parroquia de “Guangaje” en Ecuador para la cual se seleccionaron 6 instituciones.
Resultados: Se evidenció la efectividad del uso de canciones infantiles como estrategia de enseñanza para el desarrollo de la lateralidad en ubicación espacial.
Conclusiones: El empleo de canciones infantiles como estrategia de enseñanza para el desarrollo de la lateralidad en la inteligencia espacial en infantes de educación inicial puede ser provechoso para estimular entre otras cosas el desarrollo de la lateralidad en la ubicación espacial.