bluuebunny/crossref_metadata_2025_split huggingface dataset:
Efficacy of endovascular therapy for cerebral vasospasm following aneurysmal subarachnoid hemorrhage: a systematic review and meta-analysis
Authors: Ma Yu-Hu , Shang Rui , Li Si-Hao , Wang Ting , Lin Sen , Zhang Chang-Wei 
Published: April 2024

BackgroundCerebral vasospasm (CV) is a common complication of aneurysmal subarachnoid hemorrhage (aSAH), leading to increased morbidity and mortality rates. Endovascular therapy, particularly intra-arterial vasodilator infusion (IAVI), has emerged as a potential alternative treatment for CV.MethodsA systematic review and meta-analysis were conducted to compare the efficacy of endovascular therapy with standard treatment in patients with CV following aSAH. The primary outcomes assessed were in-hospital mortality, discharge favorable outcome, and follow-up favorable outcome. Secondary outcomes included major infarction on CT, ICU stay duration, and total hospital stay.ResultsRegarding our primary outcomes of interest, patients undergoing intervention exhibited a significantly lower in-hospital mortality compared to the standard treatment group, with the intervention group having only half the mortality risk (RR = 0.49, 95% CI [0.29, 0.83], p = 0.008). However, there were no significant differences between the two groups in terms of discharge favorable outcome (RR = 0.99, 95% CI [0.68, 1.45], p = 0.963) and follow-up favorable outcome (RR = 1.09, 95% CI [0.86, 1.39], p = 0.485). Additionally, there was no significant difference in major infarction rates (RR = 0.79, 95% CI [0.34, 1.84], p = 0.588). It is important to note that patients undergoing endovascular treatment experienced longer stays in the ICU (MD = 6.07, 95% CI [1.03, 11.12], p = 0.018) and extended hospitalization (MD = 5.6, 95% CI [3.63, 7.56], p &lt; 0.001). Subgroup analyses based on the mode of endovascular treatment further supported the benefits of IAVI in lowering in-hospital mortality (RR = 0.5, 95% CI [0.27, 0.91], p = 0.023).ConclusionEndovascular therapy, particularly IAVI, holds promising potential in reducing in-hospital mortality for patients with CV following aSAH. However, it did not show significant improvement in long-term prognosis and functional recovery. Further research with larger sample sizes and randomized controlled trials is necessary to validate these findings and optimize the treatment strategy for cerebral vasospasm in aSAH patients.Systematic Review Registrationhttps://www.crd.york.ac.uk/PROSPERO/, identifier: CRD42023451741.
Clinical efficacy of prophylactic intravenous immunoglobulin for elderly DLBCL patients with hypogammaglobulinemia in the COVID-19 pandemic era
Authors: Baek Dong Won , Song Ga-Young , Lee Ho Sup , Do Young Rok , Lee Ji Hyun , Yhim Ho-Young , Moon Joon Ho , Yang Deok-Hwan 
Published: April 2024

BackgroundElderly patients diagnosed with diffuse large B-cell lymphoma (DLBCL) undergoing reduced intensity R-CHOP therapy are at a heightened risk of acquiring infections, notably coronavirus disease 2019 (COVID-19) infection. This study aimed to evaluate the efficacy of intravenous immunoglobulin (IVIG) as prophylaxis against COVID-19 in this vulnerable population.MethodsA total of 125 elderly patients with DLBCL undergoing reduced intensity R-CHOP therapy were analyzed in this prospective, multicenter study. Patients with hypogammaglobulinemia were categorized into IVIG and non-IVIG groups, while those with normal immunoglobulin levels constituted the observation group. The study evaluated COVID-19 infection rates, therapy response, and safety outcomes.ResultsAmong the enrolled patients (median age: 77 years), 89 patients (71.2%) presented with hypogammaglobulinemia at diagnosis, and 56 patients enrolled in the IVIG administration group. IVIG administration remarkably reduced COVID-19 infection rates compared to non-IVIG recipients (8.9% vs. 24.6%; p =0.040). Notably, patients over 80 years old were more susceptible to COVID-19. Patients on IVIG exhibited good tolerance with manageable adverse events. Among patients with hypogammaglobulinemia who received IVIG, 40.5% of patients developed additional immunoglobulin deficiencies during chemotherapy. One or more new hypogammaglobulinemia occurred during chemotherapy in 72% of patients with hypogammaglobulinemia who did not receive IVIG, and in 61.3% of patients who did not have hypogammaglobulinemia at diagnosis.ConclusionIVIG showed promise in reducing COVID-19 infections among elderly patients with DLBCL receiving reduced intensity R-CHOP therapy. This highlights IVIG’s potential as a prophylactic measure, necessitating further investigation to optimize dosing, administration schedules, and potential interactions with vaccination strategies.
Tumor burden affects the progression pattern on the prognosis in patients treated with sorafenib
Authors: Sun Jun , Xia Dongdong , Bai Wei , Li Xiaomei , Wang Enxing , Yin ZhanXin , Han Guohong 
Published: April 2024

The progression pattern of tumors has an impact on the survival of patients with advanced hepatocellular carcinoma (HCC) and has been applied in the design of clinical trials for multiple second-line drugs. Previous research results have been contradictory, and the clinical impact of different progression patterns and their role in survival are still in question.PurposeThe study aims to analyze the impact of different progression patterns and tumor burden size on survival of HCC patients, as well as their interactions, through a retrospective cohort study.Patients and methodsThe study involved 538 patients who had undergone treatment with sorafenib and had shown radiographic progression. The progression pattern was analyzed using Cox regression by including an interaction term between progression pattern and tumor burden, which was then visualized through a graphical analysis. Tumor burden was categorized into low, medium, and high subgroups based on the six-and-twelve criteria, allowing for an exploration of the effect of progression pattern on survival in different tumor burden situations.ResultsCompared to patients with only intrahepatic progression (NIH/IHG) with an overall survival (OS) of 14.1/19.9 months and post-progression survival (PPS) of 8.1/13.1 months respectively, patients with extrahepatic lesions (NEH/EHG) had worse overall and postprogressive survival (OS: 9.3/9.2 months, PPS: 4.9/5.1 months). The hazard ratio for extrahepatic progression (NEH/EHG) compared to intrahepatic progression (NIH/IHG) at low, medium, and high tumor burden were [HR 2.729, 95%CI 1.189-6.263], [HR 1.755, 95%CI 1.269-2.427], and [HR 1.117, 95%CI 0.832-1.499], respectively.ConclusionThe study concluded that the interaction between the tumor progression patterns and tumor burden significantly affects the prognosis of HCC patients. As the tumor burden increases, the sensitivity of the patient’s risk of death to the progression pattern decreases. These findings are valuable in personalized treatment and trial design.
IMPLEMENTATION OF REGIONAL REGULATION NUMBER 3 OF 2016 CONCERNING MANAGEMENT OF WOMEN AND CHILDREN PROTECTION IN HULU SUNGAI UTARA DISTRICT
Authors: Sya'bani Arlan Agus 
Published: April 2024

The increasing number of Divorce each year In Hulu Sungai Utara Regency, this data is obtained based on surveys or direct observations in the Amuntai Religious Court. The number of divorce cases from 2014 was 651 cases, in 2015 it increased to 654 cases, although in 2016 and 2017 it decreased by around 601 and 622 but in 2018 this was only in September as many as 662 cases of this number, so there was an increase in divorce rates. The purpose of this study is to identify and analyze the implementation of Regional Regulations and analyze the obstacles in implementing Regional Regulation No. 3 of 2016 concerning the Protection of Women and Children in the North Hulu Sungai Regency.
The research method is qualitative descriptive, type and source of data, namely primary data through observation, interviews while secondary data through data available at the Office of Protection and Empowerment of Women and Children in Hulu Sungai Utara Regency, the technique used in sampling is purposive sampling technique is withdrawal of samples in purpose or can be determined in accordance with the requirements (characteristics, characteristics, characteristics, criteria). The results of the study show that in the implementation of Regional Regulation No. 3 of 2016 concerning the Implementation of Protection of Women and Children in Hulu Sungai Utara Regency, it is still not fully implemented. This can be seen where the handling of these cases has not been fully implemented, then people who are victims of domestic violence or the impact of their divorce is not all that they know about the local regulations, so they have not run properly, efficiently and effectively. So that the firmness in handling the case also cannot be implemented because the sanctions are not mentioned and the contents of the policy need to be renewed. The suggestions given for input include, among other things, providing a place for counseling and complaints about domestic violence issues, especially for the protection of women and children, there must be attention and support from the Hulu Sungai Utara District Head regarding the issue of funding in terms of supporting treatment women's protection case.
IMPLEMENTASI KEBIJAKAN ANTI PERBUATAN ASUSILA DI KAWASAN LOKALISASI DESA PASAR PANAS KECAMATAN KELUA KABUPATEN TABALONG
Authors: Riduan Akhmad 
Published: April 2024

Di provinsi Kalimantan Selatan yang kaya dengan sumber daya alam, mineral dan batu bara, telah menyerap tenaga kerja namun persoalan kemiskinan menguap hingga 206,92 ribu jiwa pada September 2020. Pusat-pusat pertumbuhan ekonomi bermunculan, tak pelak pelaku bisnis prostitusi terselubung ikut mengepak sayap seperti di Kabupaten Tabalong di beberapa lokasi. Oleh karenanya, penelitian ini bertujuan untuk mengidentifikasi, menginterpretasi, dan menganalisa implementasi kebijakan anti perbuatan asusila di kawasan lokalisasi Desa Pasar Panas Kecamatan Kelua Kabupaten Tabalong.
Guna keperluan penelitian, ditempuh metode penelitian bercorak deskriptif-kualitatif dengan sejumlah informan kunci secara purposive sampling. Data yang dikumpulkan melalui teknik observasi, wawancara, dan dokumentasi dianalisa dengan jalan data reduction, data display, dan conclusion drawing/verification. Adapun uji keabsahan data dilakukan melalui perpanjangan pengamatan, meningkatkan ketekunan, triangulasi, analisis kasus negatif, menggunakan bahan referensi, serta mengadakan member check.
Berdasarkan hasil penelitian, diketahui implementasi Peraturan Daerah Kabupaten Tabalong Nomor 8 Tahun 2018 Tentang Penyelenggaraan Ketertiban Umum Dan Ketenteraman Masyarakat di Kawasan Lokalisasi Desa Pasar Panas Kecamatan Kelua Kabupaten Tabalong tidak efektif. Pertama, dari aspek komunikasi diketahui transmisi informasi tidak berjalan, kejelasan informasi tidak terpenuhi dari sebab tiadanya transmisi informasi, dan konsistensi aparat pemerintah juga tidak terpenuhi. Kedua, dari aspek sumber daya. diketahui tersedia petugas pelaksana di lapangan terdiri dari berbagai instansi, fasilitas untuk menunjang penerapan kebijakan sudah memadai, dan anggaran telah tersedia di berbagai SKPD terkait. Ketiga, dari aspek disposisi diketahui komitmen para pelaksana dalam penerapan kebijakan tidak efektif. Keempat, dari aspek struktur birokrasi diketahui SOP dalam rangka penerapan kebijakan telah tersedia, namun fragmentasi organisasi terjadi di tingkat institusi pelaksana.
Untuk meningkatkan efektivitas dalam implementasi Peraturan Daerah Kabupaten Tabalong Nomor 8 Tahun 2018 Tentang Penyelenggaraan Ketertiban Umum Dan Ketenteraman Masyarakat di Kawasan Lokalisasi Desa Kecamatan Kelua Kabupaten Tabalong, disarankan kepada Kepala Satpol PP Kabupaten Tabalong bersama dengan instansi lainnya melakukan langkah persuasif melalui sejumlah sosialisasi, melakukan langkah koordinasi dengan pihak Pemerintah Kabupaten Barito Timur, dan melakukan monitoring secara berkesinambungan. Camat Kelua dan pemerintah desa Pasar Panas diharapkan dapat bersikap proaktif. Di luar itu, MUI Kecamatan Kelua seyogyanya dapat ikut melibatkan diri melalui upaya-upaya preventif selain dukungan dan partisipasi masyarakat setempat.
MANAJEMEN ASET TETAP PADA BADAN PENGELOLAAN KEUANGAN PENDAPATAN DAN ASET DAERAH KABUPATEN BALANGAN
Authors: Herlinda Sri Agusmila Anetha , Fitiani Fitiani 
Published: April 2024

Permasalahan berkaitan dengan Manajemen Aset Tetap pada Badan Pengelolaan Keuangan Pendapatan dan Aset Daerah Kabupaten Balangan meliputi penatausahaan arsip dan data aset tetap yang kurang terkoordinir, pengawasan yang kurang optimal dari pimpinan dan terbatasnya jumlah petugas pengelola aset tetap yang berkompeten. Tujuan penelitian ini untuk mengetahui mengetahui Manajemen Aset Tetap pada Badan Pengelolaan Keuangan Pendapatan dan Aset Daerah Kabupaten Balangan dan faktor yang mempengaruhinya.
Metode Penelitian menggunakan metode deskriptif kualitatif. Teknik pengumpulan data melalui observasi, wawancara dan dokumentasi. Kemudian Teknik penarikan informan yaitu Purposive Sampling sebanyak 10 orang. Uji kredibilitas data meliputi perpanjangan pengamatan, meningkatkan ketekunan, menggunakan bahan referensi dan membercheck.
Hasil penelitian ini menyatakan bahwa Manajemen Aset Tetap pada Badan Pengelolaan Keuangan Pendapatan dan Aset Daerah Kabupaten Balangan cukup baik dilihat dari beberapa aspek yakni: Pertama, Inventarisasi Aset dengan indikator inventarisasi fisik dinilai kurang baik, kemudian untuk Legalitas Kepemilikkan tergolong baik. Kedua, Legal Audit dengan indikator kejelasan kepemilikan tergolong baik, kemudian untuk pemeriksaan penguasaan atau pemindahtanganan dinilai sudah baik. Ketiga, Penilaian Aset dengan indikator Pengukuran kelayakkan aset dinilai sudah baik, kemudian untuk kerjasama dengan pihak independent sudah baik. Keempat, Optimalisasi Aset dengan indikator Pemisahan aset berpotensi dan tidak berpotensi dinilai kurang baik, kemudian untuk pemanfaatan Aset dinilai sudah baik, Kelima, Pengawasan dan Pengendalian dengan indikator pengawasan aset dinilai sudah baik, kemudian untuk pengendalian Aset dinilai sudah baik. Faktor yang mempengaruhi manajemen Aset Tetap pada Badan Pengelolaan Keuangan Pendapatan dan Aset Daerah Kabupaten Balangan meliputi factor penghambat yakni Pemeliharaan Aset yang kurang optimal karena upaya pemeliharaan yang kurang rutin, belum adanya petugas khusus dalam pemeliharaan aset dan Pengendalian aset yang sudah kadaluarsa masih belum teratur sesuai dengan ketentuan, kemudian faktor yang mendorong meliputi kondisi sarana dan prasarana dalam pengelolaan aset tergolong baik dan memadai dilihat dari aspek ketersediaan Gedung penyimpanan dan peralatan penunjang dalam inventarisasi seperti komputer, printer dan lain sebagainya.
Agar Manajemen Aset Tetap pada Badan Pengelolaan Keuangan Pendapatan dan Aset Daerah Kabupaten Balangan terlaksana secara optimal, disarankan kepada Kepala Badan Pengelolaan Keuangan Pendapatan dan Aset Daerah Kabupaten Balangan menambah petugas khusus untuk mengelola asset dan Pegawai lebih aktif melakukan pemeriksaan kondisi aset.
PENGARUH BAURAN PROMOSI TERHADAP VOLUME PENJUALAN PADA YAMAHA SURYANATA MOTOR AMUNTAI
Authors: Hasanah Nurul 
Published: April 2024

This research aims to know: (1) Yamaha Suryanata Motor promotion strategy year 2016-2017, (2) Cost promotion Yamaha Suryanata Motor year 2016-2017, (3) Sales volume Yamaha Suryanata Motor year 2016-2017, (4) promotion to sales volume at Yamaha Suryanata Motor 2016-2017.
This research uses qualitative and quantitative methods, this research is conducted on Yamaha Suryanata Motor, and data taken for three years starting from 2016-2017 and calculation using monthly data consisting of promotion cost and sales volume. Data collection was done by interview method, observation, and documentation. The data analysis used is quantitative method and simple linear regression.
The result of the research shows that: (1) The promotion strategy of Yamaha Suryanata Motor is done by advertising, sales promotion, and publicity, (2) Yamaha Suryanata Motor promotion expense year 2016-2017 increase, 2016 Rp 26.400.000, and year 2017 Rp 41,800,000, (3) Sales volume of Yamaha Suryanata Motor in 2016-2017 has increased, in 2016 amounted to 2680 units and in 2017 of 4225 units, (4) Test results resulted in significant effect of promotion cost on sales volume at Yamaha Suryanata Motor, with thitung = 15.29 is greater than ttable = 1.714
CRIMINAL LIABILITY FOR BRIBERY: BURNING ISSUES
Authors: Багаутдинов Флер Нуретдинович 
Published: April 2024

Введение: в статье анализируются положения статей 290, 291, 2911, 2912 УК РФ, предусматривающих уголовную ответственность за различные виды взяточничества. Материалы и методы: основу исследования составили диалектико-материалистический, логический, исторический, системно-структурный, сравнительно-правовой, статистический методы. Проанализированы статистические сведения о состоянии и структуре коррупционной преступности в Российской Федерации. Результаты исследования: предложены изменения в действующие статьи Уголовного кодекса Российской Федерации, предусматривающие уголовную ответственность за взяточничество. Обсуждение и заключение: автор приходит к выводу, что усилению борьбы со взяточничеством может способствовать расширение оснований для освобождения взяткодателей от уголовной ответственности.
Introduction: the author examines the criminalization of bribery in Articles 290, 291, 2911, and 2912 of the Criminal Code of Russia. Materials and Methods: the research is based on dialectical and materialistic, logical, historical, systemic, comparative legal, and statistical methods. The results include proposed amendments to the relevant Articles of the Criminal Code of Russia. Discussion and Conclusions: the author comes to the conclusion that the criteria for excluding criminal responsibility for bribe givers should be expanded.
Environmental DNA-based biodiversity profiling along the Houdong River in north-eastern Taiwan
Authors: Lin Chieh-Ping , Huang Chung-Hsin , Padgett Trevor , Bucay Mark Angelo , Chen Cheng-Wei , Shen Zong-Yu , Chiu Ling , Tseng Yung-Che , Yu Jr-Kai , Wang John , Wang Min-Chen , Hoh Daphne 
Published: April 2024

This paper describes two datasets: species occurrences, which were determined by environmental DNA (eDNA) metabarcoding and their associated DNA sequences, originating from a research project which was carried out along the Houdong River (猴洞坑), Jiaoxi Township, Yilan, Taiwan. The Houdong River begins at an elevation of 860 m and flows for approximately 9 km before it empties into the Pacific Ocean. Meandering through mountains, hills, plains and alluvial valleys, this short river system is representative of the fluvial systems in Taiwan. The primary objective of this study was to determine eukaryotic species occurrences in the riverine ecosystem through the use of the eDNA analysis. The second goal was, based on the current dataset, to establish a metabarcoding eDNA data template that will be useful and replicable for all users, particularly the Taiwan community. The species occurrence data are accessible at the Global Biodiversity Information Facility (GBIF) portal and its associated DNA sequences have been deposited in the European Nucleotide Archive (ENA) at EMBL-EBI, respectively. A total of 12 water samples from the study yielded an average of 1.5 million reads. The subsequent species identification from the collected samples resulted in the classification of 432 Operational Taxonomic Units (OTUs) out of a total of 2,734. Furthermore, a total of 1,356 occurrences with taxon matches in GBIF were documented (excluding 4,941 incertae sedis, accessed 05-12-2023). These data will be of substantial importance for future species and habitat monitoring within the short river, such as assessment of biodiversity patterns across different elevations, zonations and time periods and its correlation to water quality, land uses and anthropogenic activities. Further, these datasets will be of importance for regional ecological studies, in particular the freshwater ecosystem and its status in the current global change scenarios.
The datasets are the first species diversity description of the Houdong River system using either eDNA or traditional monitoring processes.
La « Classe 22 » : une jeunesse socialiste et marxiste face aux années 1930
Authors: Fourcaut Matteo 
Published: April 2024

Une revue socialiste méconnue, Révolte (1931-1934), donne à voir l’expression de « l’esprit des années trente » dans une SFIO marquée par la sortie de guerre et la défaite de Tours. Au sein de cette petite tribune parisienne, un groupe de jeunes militants cherche à rénover la doctrine socialiste, « chose vieille, trop connue », et à redresser la « vieille maison » pour qu’elle puisse conquérir les masses nouvelles et assumer enfin ses responsabilités en prenant le pouvoir. Cette « Classe 22 », génération tout à la fois effrayée et fascinée par la modernité de l’après-guerre, élabore un discours et une pensée propres et singuliers, qui ne trouvent que peu d’échos dans la gauche française. Étouffée par un Parti qui cherche à maintenir coûte que coûte l’unité d’une famille socialiste fragile, puis invisibilisée par le Front populaire qui est le triomphe de la génération suivante, la Classe 22 échoue à exister. Cette génération entravée donne tout de même à voir la manière dont le phénomène de « l’esprit des années trente » a infusé dans le socialisme français.
Pauvreté, inégalités et développement : entretien avec François Bourguignon
Authors: Bresson Florent 
Published: April 2024

Nous apprenions fin 2022 le décès de Martin Ravallion qui aura marqué de son empreinte l’analyse de la pauvreté dans le monde durant plus de trois décennies. Un hommage, sous forme de table ronde, lui a été rendu durant l’ICDE 2023. François Bourguignon, organisateur de la table ronde, revient avec nous sur la carrière de celui qu’il a nommé comme directeur de la recherche de la Banque mondiale lorsqu’il était lui-même vice-président et économiste en chef de l’institution. L’occasion aussi de parler des évolutions de la discipline et des perspectives futures en matière de pauvreté dans le monde 1 . Codes JEL : I32, O15.