bluuebunny/crossref_metadata_2025_split huggingface dataset:
A Relativistic Double Neutron Star Binary PSR J1846-0513
Authors: Zhao D. , Wang N. , Yuan J. P. , Li D. , Wang P. , Xue M. Y. , Zhu W. W. , Miao C. C. , Yan W. M. , Wang J. B. , Yao J. M. , Wu Q. D. , Wang S. Q. , Sun S. N. , Kou F. F. , Chen Y. T. , Dang S. J. , Feng Y. , Liu Z. J. , Miao X. L. , Meng L. Q. , Yuan M. , Niu C. H. , Niu J. R. , Qian L. , Wang S. , Xie X. Y. , Xiao Y. F. , Yue Y. L. , You S. P. , Yu X. H. , Zhao R. S. , Yuen R. , Zhou X. , Zhang L. , Wang Y. B. , Wu J. F. , Gan Z. Y. , Sun Z. Y. , Wang C. J. 
Published: March 2024

Abstract
We report the timing analysis of PSR J1846−0513, a pulsar discovered by the Five-hundred-meter Aperture Spherical radio Telescope (FAST) in Commensal Radio Astronomy FAST Survey. The pulsar possesses a spin period of 23.36 ms and a spin-down rate (

P

̇

) of 1.0106(3) × 10−18 s s−1, and it is located in an eccentric orbit (e ∼0.208) with an orbital period of 0.61 days. The characteristic age and surface magnetic field of the pulsar are found to be 366.62 Myr and 4.9178 × 109 G, respectively, indicating that it is a recycled pulsar. Using over two years of timing data, we measure the periastron advance

ω

̇

= 0.8956(8) deg yr−1. By assuming that this effect is purely relativistic, we have estimated the total mass M = 2.6287(35)M
⊙ and obtained an upper limit for the pulsar mass and a lower limit for the companion’s mass. Our results indicate that this is a double neutron star system.
La peur est-elle efficace dans un contexte français de lutte contre les comportements tabagiques ?
Authors: Gallopel-Morvan Karine 
Published: March 2024

Est-il pertinent de faire peur dans un contexte français de lutte contre le tabac ? Afin de traiter cette question, l’article commence par résumer les modèles théoriques de l’influence de la peur sur les réactions des consommateurs, avant de présenter une expérimentation menée sur 489 étudiants. Les conclusions de cette étude révèlent que la peur est efficace pour inciter des non-fumeurs à ne pas fumer et des fumeurs à diminuer leur consommation tabagique. En revanche, lorsqu’il s’agit de l’arrêt du tabac, un message phobique doit être accompagné d’un message de soutien qui rassure le fumeur quant à sa capacité à arrêter de fumer.
La diversité des états affectifs dans un point de vente
Authors: Lichtlé Marie-Christine , Plichon Véronique 
Published: March 2024

Les stimuli sensoriels liés à l’atmosphère du point de vente peuvent affecter le comportement du consommateur. Certains distributeurs cherchent ainsi à valoriser l’expérience vécue par le chaland, en lui faisant éprouver différentes sensations. Toutefois, la diversité des réactions affectives pouvant être créées dans un environnement commercial n’a pas encore été mise en évidence. C’est l’objet de cette étude : elle montre que les états affectifs peuvent être représentés par six dimensions et sont d’intensité variable ; en outre, il est possible de caractériser certaines enseignes de la distribution par le type et l’intensité des réactions affectives ressenties.
ROMI : Une révolution dans la pensée et les pratiques en marketing
Authors: Merunka Dwight , Kazmierczak Jean-Bernard 
Published: March 2024

La direction générale des entreprises et les directeurs marketing sont convaincus du bien fondé de la mise en place de nouvelles mesures d’efficacité des actions marketing. Les modèles et les métriques qui permettent d’évaluer l’impact financier des dépenses engagées sur les différents éléments du mix marketing sont regroupés sous le vocable de ROMI (« Return on Marketing Investment » ou retour sur les investissements marketing). Nous décrivons les difficultés et les dangers liés à la mise en place de cette démarche et de ces mesures et montrons la nécessité de leur mise en œuvre.
La bifurcation précoce des jeunes diplômé·es : processus et enchaînements d’évènements impliqués
Authors: Coënt Ludivine , Diridollou Melvin , Olry-Louis Isabelle 
Published: March 2024

Alors que les bifurcations professionnelles constituent un phénomène relativement bien documenté en sciences humaines et sociales, le cas de jeunes diplômé·es ayant bifurqué juste après l’obtention de leur diplôme, sans jamais avoir exercé le métier pour lequel ils ou elles ont été formé·es initialement, apparaît plus inédit. L’article examine cette question à la lumière non seulement des approches transitionnelles classiques, mais aussi de celles qui analysent les bifurcations professionnelles au sein des parcours de vie. Douze entretiens de jeunes diplômés en bifurcation précoce ont fait l’objet de trois analyses distinctes au regard : 1) de leur contenu thématique, 2) du modèle d’analyse structurale biographique, 3) et du modèle théorique Push, Pull, anti-Push, anti-Pull (2PAP). Tout en montrant de fortes similitudes entre les processus et les enchaînements d’événements impliqués dans les bifurcations précoces et les bifurcations professionnelles classiques, notamment quant à la place prise par l’idéal professionnel, par autrui, par les enchaînements d’évènements ordinaires ou hasardeux, les résultats mettent en évidence quelques spécificités propres à la socialisation professionnelle des jeunes diplômé·es et suggèrent un impact fort joué par le Covid-19 dans leurs trajectoires.
Comparison between perfusion index, pleth variability index, and pulse pressure variability for prediction of hypotension during major abdominal surgery under general anaesthesia: A prospective observational study
Authors: Gunashekar Satheesh , Kaushal Ashutosh , Kumar Ajit , Gupta Priyanka , Gupta Namrata , C.S. Pooja 
Published: March 2024

Background and Aims:
Short-term hypotension after general anaesthesia can negatively impact surgical outcomes. This study compared the predictive potential of the pleth variability index (PVI), pulse pressure variability (PPV), and perfusion index (PI) for anaesthesia-induced hypotension. This study’s primary objective was to evaluate the predictive potential of PI, PVI, and PPV for hypotension.

Methods:
This observational study included 140 adult patients undergoing major abdominal surgery under general anaesthesia. Mean arterial pressure, heart rate, PVI, PPV, and PI were collected at 1-min intervals up to 20 min post anaesthesia induction. Hypotension was assessed at 5-min and 15-min intervals. Receiver operating characteristic (ROC) curves were plotted to determine the diagnostic performance and best cut-off for continuous variables in predicting a dichotomous outcome. Statistical significance was kept at P < 0.05.

Results:
Hypotension prevalence within 5 and 15 min of anaesthesia induction was 36.4% and 45%, respectively. A PI cut-off of <3.5 had an area under the ROC curve (AUROC) of 0.647 (P = 0.004) for a 5-min hypotension prediction. The PVI’s AUROC was 0.717 (P = 0.001) at cut-off >11.5, while PPV’s AUROC was 0.742 (P = 0.001) at cut-off >12.5. At 15 min, PVI’s AUROC was 0.615 (95% confidence interval 0.521–0.708, P = 0.020), with 54.9% positive predictive value and 65.2% negative predictive value.

Conclusion:
PVI, PPV, and PI predicted hypotension within 5 min after general anaesthesia induction. PVI had comparatively higher accuracy, sensitivity, specificity, and positive predictive value than PI and PPV when predicting hypotension at 15 min.
Comparison of the effect of intravenous phenylephrine and norepinephrine boluses for post-spinal hypotension on neonatal outcome in elective caesarean section: A randomised controlled trial
Authors: Saha Prerona , Konwar Chandita , Pandey Aditya , Bharali Prabal 
Published: March 2024

Background and Aims:
There is limited data on the effects of norepinephrine on neonatal outcomes and maternal complications relative to other vasopressors. The study aimed to compare neonatal outcomes and maternal complications after bolus intravenous doses of phenylephrine and norepinephrine for post-spinal hypotension in elective caesarean section women.

Methods:
This randomised study was done on 100 elective caesarean section women under spinal anaesthesia. Block randomisation divided women into two groups to receive intravenous phenylephrine 50 μg bolus (Group A) or norepinephrine 5 μg bolus (Group B) following post-spinal hypotension. Groups were evaluated and compared for umbilical arterial blood gas analysis, birth weight, APGAR (appearance, pulse, grimace, activity, and respiration) score, maternal haemodynamics, and complications. Kolmogorov-Smirnov and Shapiro-Wilk tests were used to verify data normality. Independent samples t-test or Mann-Whitney U test was employed to compare continuous variables based on data normality, and the Chi-square test was used to determine categorical variable associations.

Results:
Demographic characteristics of women were found to be comparable between groups. Umbilical arterial potential of hydrogen, partial pressure of oxygen, partial pressure of carbon dioxide, base excess, bicarbonate, birth weight, and APGAR scores were comparable across groups, showing no significant differences (P > 0.05). Groups had similar maternal haemodynamic characteristics and episodes of nausea, vomiting, and chest pain across groups without statistical significance (P > 0.05).

Conclusion:
No notable distinction was found between neonatal outcomes and maternal complications between phenylephrine and norepinephrine bolus regimens. Norepinephrine can be used as an alternative to phenylephrine post-spinal hypotension in women undergoing elective caesarean section.
Three cases of pseudoepitheliomatous hyperplasia mimicking squamous cell carcinoma of the foot: A case series
Authors: Arulselvan M. , Muthurathinam Trishna Vaishali 
Published: March 2024

Abstract
Pseudoepitheliomatous hyperplasia (PEH) is a benign condition characterized by hyperplasia and proliferation of the epidermis and adnexal epithelium which can mimic squamous cell carcinoma (SCC). In our first case, a 55-year-old female with a prior history of split skin graft presented with dark verrucous growth over the graft site with a nonhealing ulcer of 3 cm × 2 cm seen over the ventral aspect of the left foot. Our second case, a 59-year-old male with a prior history of split skin grafting presented with dark verrucous growth and pain over the right forefoot for 3 months. The third case, a 58-year-old man with diabetic foot ulcer with verrucous growth over the toes. In all the cases, the biopsy was done and diagnosed to be PEH. We report this case series of PEH for the proper distinction from the SCC of the skin.
An institutional study on accuracy of freehand cervical C1 C2 screws placement by knock and drill technique in craniovertebral anomalous bony anatomy: An evaluation of more than 600 screws based on SGPGI screw accuracy criteria
Authors: Sasapardhi Sudhir Bisan , Verma Pawan Kumar , Srivastava Arun Kumar , Das Kuntal Kanti , Kumar Ashutosh , Dikshit Priyadarshi , Maurya Ved Prakash , Bhaisora Kamlesh Singh , Mehrotra Anant , Jaiswal Awadhesh Kumar , Mishra Prabhaker , Behari Sanjay , Kumar Raj , Mishra Harshit , Shahare Kalyani 
Published: March 2024

ABSTRACT

Purpose:
To assess the accuracy of freehand cervical C1 C2 screws placement by knock and drill (K and D) technique in craniovertebral anomalous bony anatomy.

Materials and Methods:
From January 2017 to December 2022, 682 consecutive C1 C2 screws in 215 patients with craniovertebral junction (CVJ) anomalies were enrolled. All patients underwent posterior fixation with K and D technique without any fluoroscopic guidance. The patient’s demographic details, clinical details, radiological details, major intraoperative events, and postoperative complications were noted. The screws malposition grades and direction on CT images in the axial and sagittal plane were defined as new per proposed “SGPGI accuracy criteria.” All patients had a clinical evaluation at 3-month follow-up.

Results:
Total 682 C1, C2 screws were placed in 215 patients for CVJ anomalies using K and D technique. The accuracy of screws placement by freehand technique was 84.46% (576/682). So with technique explained the rate of malplacement in simple (16.35%) and complex (15.19%) groups were almost comparable and comparison difference was not significant (P = 0.7005).

Conclusion:
The freehand technique, as described, is effective in cases of anomalous bony anatomy, and it is mandatory in complex CVJ anomalies. The accuracy of screw placement and VA injury is comparable with major studies. This technique is supposedly cost-effective and less hazardous to both health-care workers and patients.
Correction of cervical kyphoscoliosis, bisected spinal cord, and vertebral artery to epidural vein fistula in neurofibromatosis type 1
Authors: LeFever Devon , Hanks Thomas , Kumar Rakesh , Louie Philip , Leveque Jean-Christophe 
Published: March 2024

ABSTRACT
Neurofibromatosis-1 (NF1) presents complex challenges due to its multisystemic effects, including kyphoscoliosis, dural ectasia, and arteriovenous fistulas (AVF). We present a case of a 31-year-old male with NF1 exhibiting severe cervical kyphoscoliosis, dural ectasia, a bisected cervical cord, and an arteriovenous fistula, highlighting the intricacies of managing such intricate cases. Rapid weakening in the patient’s right arm and leg prompted imaging revealing severe cervical kyphotic deformity and a dural fold dividing the spinal cord. Surgical intervention addressed a high-flow arteriovenous fistula involving the right vertebral artery and an epidural vein, necessitating sacrifice of the artery. Posterior fusion and laminectomy were performed, resulting in stable neurological status postoperatively and significant improvement in sensory loss and weakness at three months. This case underscores the importance of a tailored posterior-only approach, involving dural fold release, to allow the spinal cord to relocate to a less tense position, thus demonstrating effective decompression in complex NF1 cases with concurrent kyphotic deformity and vertebral artery AVF.
The demographic, clinical, and management differences between traumatic dens fracture patients with and without simultaneous atlas fractures
Authors: Cloney Michael Brendan , Texakalidis Pavlos , Roumeliotis Anastasios G. , Thirunavu Vineeth , Shlobin Nathan A. , Swong Kevin , El Tecle Najib , Dahdaleh Nader S. 
Published: March 2024

ABSTRACT

Introduction:
Atlas fractures often accompany traumatic dens fractures, but existing literature on the management of simultaneous atlantoaxial fractures is limited.

Methods:
We examined all patients with traumatic dens fractures at our institution between 2008 and 2018. We used multivariable logistic regression and ordinal logistic regression to identify factors independently associated with presentation with a simultaneous atlas fracture, as well myelopathy severity, fracture nonunion, and selection for surgery.

Results:
Two hundred and eighty-two patients with traumatic dens fractures without subaxial fractures were identified, including 65 (22.8%) with simultaneous atlas fractures. The distribution of injury mechanisms differed between groups (χ2
P = 0.0360). On multivariable logistic regression, dens nonunion was positively associated with type II fractures (odds ratio [OR] = 2.00, P = 0.038) and negatively associated with having surgery (OR = 0.52, P = 0.049), but not with having a C1 fracture (P = 0.3673). Worse myelopathy severity on presentation was associated with having a severe injury severity score (OR = 102.3, P < 0.001) and older age (OR = 1.28, P = 0.002), but not with having an atlas fracture (P = 0.2446). Having a simultaneous atlas fracture was associated with older age (OR = 1.29, P = 0.024) and dens fracture angulation (OR = 2.62, P = 0.004). Among patients who underwent surgery, C1/C2 posterior fusion was the most common procedure, and having a simultaneous atlas fracture was associated with selection for occipitocervical fusion (OCF) (OR = 14.35, P = 0.010).

Conclusions:
Among patients with traumatic dens, patients who have simultaneous atlas fractures are a distinct subpopulation with respect to age, mechanism of injury, fracture morphology, and management. Traumatic dens fractures with simultaneous atlas fractures are independently associated with selection for OCF rather than posterior cervical fusion alone.
Surgical strategies in the management of atlantoaxial dislocation in Down syndrome
Authors: Joseph Vivek Baylis , Ganesh Swaminathan , Panicker Tony Varghese 
Published: March 2024

ABSTRACT

Aims:
To study the clinicoradiological features and treatment outcomes of atlantoaxial dislocation (AAD) in Down syndrome.

Settings and Design:
Retrospective case series.

Subjects and Methods:
A retrospective chart and radiology review of 9 Down syndrome patients with AAD managed at our center from 2007 to 2018.

Statistical Analysis Used:
Chi-squared/Fisher’s exact test.

Results:
There were 4 males and 5 females (n = 9). The median age was 14 years (interquartile range [IQR]: 7–15.5). 77.7% (7/9) of patients had severe spasticity (Nurick Grades 4 and 5). The median duration of symptoms was 9 months (IQR: 5–39). The AAD was reducible in all (n = 9) cases. Eight (88.8%) patients had os odontoideum. The mean atlantodental interval (ADI) was 8.5 mm (±2.9). T2W cord hyperintensity was seen in 66.6% (6/9). Posterior C1–2 transarticular fixation was done in 8 and occipitocervical fusion in 1 patient. Follow-up of more than 6 months (7–57 months) was available in 8/9 (88.9%) patients. There was a significant improvement in spasticity (n = 8, mean Nurick Grade 1.7 (±1.1), P = 0.003). Follow-up radiographs (n = 8) showed good reduction and fusion. A preoperative bedbound patient with poor respiratory reserve expired at 10 months following surgery. There were no other complications.

Conclusions:
Posterior surgical approach for AAD in Down syndrome resulted in good alignment and fusion, with excellent clinical improvement. Patients with elevated PCO2 are poor surgical candidates and require home ventilation facility.
Advancing insights into recurrent lumbar disc herniation: A comparative analysis of surgical approaches and a new classification
Authors: Musa Gerald , Abakirov Medetbek Dzhumabekovich , Chmutin Gennady E. , Mamyrbaev Samat Temirbekovich , Ramirez Manuel De Jesus Encarnacion , Sichizya Kachinga , Kim Alexander V. , Antonov Gennady I. , Chmutin Egor G. , Hovrin Dmitri V. , Slabov Mihail V. , Chaurasia Bipin 
Published: March 2024

ABSTRACT

Background:
The management of recurrent lumbar disc herniation (rLDH) lacks a consensus. Consequently, the choice between repeat microdiscectomy (MD) without fusion, discectomy with fusion, or endoscopic discectomy without fusion typically hinges on the surgeon’s expertise. This study conducts a comparative analysis of postoperative outcomes among these three techniques and proposes a straightforward classification system for rLDH aimed at optimizing management.

Patients and Methods:
We examined the patients treated for rLDH at our institution. Based on the presence of facet resection, Modic-2 changes, and segmental instability, they patients were categorized into three groups: Types I, II, and III rLDH managed by repeat MD without fusion, MD with transforaminal lumbar interbody fusion (TLIF) (MD + TLIF), and transforaminal endoscopic discectomy (TFED), respectively.

Results:
A total of 127 patients were included: 52 underwent MD + TLIF, 50 underwent MD alone, and 25 underwent TFED. Recurrence rates were 20%, 12%, and 0% for MD alone, TFED, and MD + TLIF, respectively. A facetectomy exceeding 75% correlated with an 84.6% recurrence risk, while segmental instability correlated with a 100% recurrence rate. Modic-2 changes were identified in 86.7% and 100% of patients experiencing recurrence following MD and TFED, respectively. TFED exhibited the lowest risk of durotomy (4%), the shortest operative time (70.80 ± 16.5), the least blood loss (33.60 ± 8.1), and the most favorable Visual Analog Scale score, and Oswestry Disability Index quality of life assessment at 2 years. No statistically significant differences were observed in these parameters between MD alone and MD + TLIF. Based on this analysis, a novel classification system for recurrent disc herniation was proposed.

Conclusion:
In young patients without segmental instability, prior facetectomy, and Modic-2 changes, TFED was available should take precedence over repeat MD alone. However, for patients with segmental instability, MD + TLIF is recommended. The suggested classification system has the potential to enhance patient selection and overall outcomes.
Diagnostic threshold and performance of anion gap in screening for high anion gap metabolic acidosis
Authors: Chionh Chang Yin , Tien Carolyn Shan-Yeu ,   Changi REnal MEdicine REsearch (CREMERE) Group, Yeon Wenxiang 
Published: March 2024

Abstract

Introduction:
The anion gap (AG) is commonly used to screen for acid–base disorders. It was proposed that the cut-off for high anion gap metabolic acidosis (HAGMA) may be lower with current laboratory techniques, although modern laboratory equipment are still calibrated to familiar reference ranges established with earlier techniques. The appropriate cut-off for HAGMA is unclear. This study aimed to assess the performance of AG as a screening test for HAGMA and to determine the optimal diagnostic threshold of AG for HAGMA.

Methods:
This was a retrospective analysis of a large, anonymised dataset extracted by computerised protocol from 2017 to 2019. All inpatients with blood samples taken for organic acids (lactate, ketone or salicylate) paired with a metabolic panel were included. The target condition was HAGMA secondary to elevated blood lactate, ketone and/or salicylate. Sensitivity for HAGMA was explored at various AG cut-off levels.

Results:
Of 16,475 patients, 2,621 had organic acidosis. Median age was 65 years, and median estimated glomerular filtration rate was 70 mL/min/1.73 m2. With organic acidosis, the median AG was 23 (interquartile range [IQR] 20–29) mEq/L, while without organic acidosis, the median AG was 16 (IQR 14–19) mEq/L. The area under the curve-receiver operating characteristic of AG for HAGMA was 0.873. Desired sensitivity for HAGMA was set at ≥95%, and this was found with an AG threshold of ≥15 mEq/L (sensitivity 98.1%, specificity 34.0%).

Conclusion:
The recommended AG threshold value is ≥15 mEq/L with a high sensitivity for HAGMA. The AG should always be interpreted with the clinical context, and it should be repeated as the clinical picture evolves.