bluuebunny/crossref_metadata_2025_split huggingface dataset:
Challenges of Implementing Telemedicine Technology: A systematized Review
Authors: Hadian Marziye , Jelodar Zahra Khakdel , Khanbebin Mohammadreza Jabbari , Atafimanesh Pezhman , Asiabar Ali Sarabi , Dehagani Seyed Mehdi Hejazi 
Published: February 2024

Abstract

Background:
Today, the technologies in the world are rapidly evolving, and global infrastructure of information is spreading rapidly. The health system of different countries is facing a variety of challenges in order to apply telemedicine services. The aim of this study was to determine the challenges facing the health system of different countries in the application of telemedicine.

Method:
The present research was conducted in 2022 as a systematized review of studies related to challenges of telemedicine. In this study, Preferred Reporting Items for Systematic Reviews (PRISMA) and Critical Appraisal Skills Program (CASP) guidelines were used to assess the articles. The keywords “telemedicine,” “telehealth,” “E-health,” and “tele care” were used in combination with the Boolean operators OR and AND. The ISI Web of Science, PubMed, Scopus, Science Direct, Ovid, Pro Quest, Wiley, and Google Scholar were searched.

Results:
In this study, based on the search strategy, databases were searched from January 2012 to January 2022, and in the final stage, analysis was performed on 27 selected identified articles. The use of telemedicine technology faced major formality and legality, required bandwidth, development of multilingual systems, economic efficiency, available patterns, payment for services, moral barriers, social status, differences and national and legal contradictions in the world, lack of insurance coverage challenges, and so on. Recognizing gaps and challenges can provide a way to fill these gaps and create opportunities for improvement.

Conclusions:
Utilizing telemedicine technology can be considered as an effective step in the health system. This technology has weaknesses that may challenge it. Successful application of telemedicine technology cannot be very effective without removing these barriers.
Standard manufacturing process of Aadityapaka Guduchi Taila with unique Pakavidhi (Aadityapaka): a Sneha Kalpana
Authors: Bala Anku , Lakhran Ashok Kumar , Kotecha Mita , Chaudhary Krutika 
Published: February 2024

Abstract

BACKGROUND:
Since the Vedic era, Ayurveda has promoted natural components to develop a healthy lifestyle and eradicate the disease’s underlying cause by restoring homeostasis. Recently, the acceptability of herbal formulations has grown profusely and garnered global attention. Ayurveda system is enriched with single herbs and polyherbal formulations prepared with different processes. Standardization of a polyherbal formulation process is more essential. Aadityapaka Guduchi Taila (AGT) is a formulation of Chakradutta for Hair fall and is prepared with a peculiar manufacturing process using sunlight.

METHODS:
AGT was prepared after proper identification and authentication of ingredients as per the standards mentioned in the API. Pharmacognostic and pharmaceutical analyses were carried out to adequately assess the finished product from the viewpoints of efficacy, and quality.

RESULTS:
The oil prepared from Aadityapaka vidhi was dark orange in color, Ugragandha (strong) in odor pertaining to Jatamansi, and had a greasy consistency. The loss of oil was observed more in the process due to the powder texture of the ingredients.

CONCLUSION:
There are very few scientific references reported for the Adityapaka process (oil prepared in sunlight). The current study illustrated the standardization of AGT process. The study may be employed as a reference for future research.
Formulation and evaluation of new herbal nutraceutical tablet for the treatment of diabetes mellitus
Authors: Debnath Bikash , Manna Kuntal , Singh Waikhom Somraj , Goswami Sanchari 
Published: February 2024

Abstract

BACKGROUND:
Herbal nutraceutical dosage forms a dietary supplement that improves various chronic diseases. This study aimed to formulate and evaluate new herbal nutraceutical tablets and assess antihyperglycemic and antihyperlipidemia effects in ob/ob mice.

METHODS:
A herbal nutraceutical tablet was prepared by the wet granulation method. Proximate composition was determined by the Association of Official Analytical Chemists methods. The high-performance liquid chromatography method was used for the estimation of water-soluble vitamins and fat-soluble vitamins. An atomic absorption spectrophotometer was used for analyzing trace elements. Oral glucose tolerance tests and biochemicals were analyzed to assess antihyperglycemic and antihyperlipidemia effects in ob/ob mice.

RESULTS:
Herbal nutraceutical tablet contains a good amount of energy. Iron, sodium, potassium, phosphorus, magnesium, iodine, copper, zinc, and calcium were present in the newly formulated herbal tablets. A reasonable amount of water-soluble and fat-soluble vitamins were also present. Administration of newly developed herbal nutraceutical tablets (200 mg/kg) in ob/ob mice significantly improved the antihyperglycemic and antihyperlipidemia effects compared to the standard drug metformin (200 mg/kg).

CONCLUSIONS:
Based on these findings, a newly formulated herbal nutraceutical tablet may be recommended as a dietary supplement and can be utilized as an active type 2 diabetes drug.
Determination of total phenolic content, total antioxidants, and GC–MS analysis of two different solvent extracts of Merremia quinquefolia (L.) Hallier f. Twigs grown in Bundelkhand region of India
Authors: Verma Kritika , Yadav Surabhi , Zahra Kaneez 
Published: February 2024

Abstract

BACKGROUND:

Merremia quinquefolia (L.) Hallier f. (MQ) is a species of Merremia belonging to the family Convolvulaceae. It is a herbaceous prostrate or climbing vine that is well-known for its ability to heal burns, scalds, and sores. This study aimed to estimate the total phenolic content and antioxidants and characterize the phytochemical constituents of methanolic and aqueous extracts of MQ twigs.

METHODS:
The dried powdered twigs of MQ were extracted with methanol and distilled water by hot percolation method. These two prepared extracts were analyzed by gas chromatography-mass spectrometry (GC–MS) to characterize the chemical constituents of crude extracts. The Folin–Ciocalteu reagent method was used to determine the total phenolic content of both extracts, and their total antioxidant content was determined using a phospho-molybdate assay.

RESULTS:
The results of GC–MS analysis revealed the presence of 17 major peaks of different phytochemicals in the methanol extract and 16 major peaks of various phytochemicals in the distilled water extract. These phytochemicals were identified by comparing their retention time and mass spectra with the literature. In addition, the methanol extract contained high phenolic content but less antioxidant than distilled water extract.

CONCLUSION:
This study shows that twigs of the MQ plant are rich sources of bioactive compounds that can play an important role in drug design to deal with many diseases.
Comparative Evaluation of Antimicrobial Activity of Herbal and Nonherbal Root Canal Irrigants on Enterococcus faecalis: An in vitro Study
Authors: Ganesh Greeshma , Chandru T. P. , Peedikayil Faizal C. , Kottayi Soni , Divakar Neethu P. , Aparna T. P. 
Published: February 2024

Introduction:

Enterococcus faecalis is one of the most prevalent pathogens in infected root canals. Even though the role of irrigants in controlling pathogens is well established, there is a chance for drug resistance and cytotoxicity in using chemical irrigants, Therefore newer researches have forced the man to look the herbal way.

Aim of the Study:
This study aims to evaluate and compare the anti-bacterial effects of nonherbal and herbal root canal irrigants on E. faecalis.

Methodology:
The study was conducted on 110 permanent extracted human teeth each root canal was inoculated with a culture suspension of E. faecalis and then randomly assigned into groups, (i) Herbal group (QMix™ 2 in 1, Endoseptone, Biopure MTAD) and (ii) Nonherbal group (Morinda citrifolia juice, Triphala juice, Coconut milk), and control group (Sodium hypochlorite and Distilled water). Colony forming units (CFUs) were evaluated and counted at baseline (S0), immediatedly after irrigation (S1) and after 3 days (S2). The Friedman two-way ANOVA was used to compare the obtained mean of log CFU.

Results:
Both the herbal and nonherbal groups had a significant reduction in the number of CFUs. The greatest anti-microbial effects were observed in nonherbal group against E. faecalis.

Conclusion:
While the herbal group also demonstrated significant reductions, the nonherbal group experienced the greatest overall anti-microbial effects of the various irrigants. Research into the herbal irrigants is necessary since they have the potential to be effective irrigants.
Limb Salvage in a Mangled Foot Using Combined External and Internal Fixation
Authors: Kaul Rajiv , Iqbal Mohammed Schezan , Akhoon Neha 
Published: February 2024

Abstract
Historically, mangled extremities were generally treated with a primary amputation. Advancements in surgical repair and reconstruction have increased the possibility of salvage in the limbs damaged by high-energy trauma, with a reasonably functional outcome. The Mangled Extremity Severity Score is a useful guide for evaluating and managing a crushed limb. However, most literature does not support the practicality of any particular scoring system to discriminate between the limbs requiring amputation and those likely to be salvaged successfully. In young patients, without significant comorbidities and borderline injury scores, an earnest attempt at limb salvage should be made. The case report highlights how shared and timely decision-making coupled with the innovative use of the Ilizarov apparatus, in a seemingly distraught situation, led to successful salvage and restoration of function.
Complications and Errors in Guided Growth Surgery
Authors: Burghardt Rolf D. , von der Heydt Kevin , Heckel Natascha , Herzenberg John E. , Burgkart Rainer 
Published: February 2024

Abstract

Objectives:
Guided growth (GG) is a widely used treatment option in growing children with varus/valgus deformities (VVD) or limb length discrepancy (LLD). The outcomes of these different techniques have been widely reported. There is, however, a paucity of reports addressing adverse events (AEs) of GG. We reviewed the clinical results of GG for VVD or LLD with an emphasis on describing AE.

Methods:
AEs were collected and analyzed for all cases treated at a single European institution with GG for VVD or LLD. AEs were classified into five categories: improper indications, malpositioned implants, errors in timing of hardware removal, general surgical complications, and implant failures/incomplete removals.

Results:
During the defined time period, 117 patients for LLD and 106 patients were operated for VVD. In total, there were 111 AEs (LLD = 60, VVD = 51). These were subdivided into categories: improper indications (31) (LLD = 20, VVD = 11), malpositioned implants (26) (LLD = 23, VVD = 3), errors in timing of hardware removal (25) (LLD = 9, VVD = 16), general surgical complications (20) (LLD = 5, VVD = 15), and implant failures/incomplete removals (9) (LLD = 3, VVD = 6).

Conclusions:
Most AEs can be avoided through correct radiological analysis of limb alignment and a basic understanding of the principles of GG. Furthermore, it is essential to place the implant precisely and ensure regular follow-up evaluations. While ostensibly a simple procedure, therapeutic decisions regarding planning of GG need to be thoughtfully made, the actual performance of the GG surgery should not be relegated to an under-supervised junior team member. Careful follow-up is imperative.
Comparing the Efficacy of Different Maintenance Intervals on Preventing Disease Recurrence in Patients with A History of Periodontal Treatment
Authors: Ganji Kiran K. , Alam Mohammad K. , Alkhwaitm Mohammed Ali , Al-Hammad Kholood A S , Sultan Sherif 
Published: February 2024

ABSTRACT

Background:
Scheduled maintenance appointments after periodontal treatment are very much critical for the success of the treatment. This is necessary for patients seeking to prevent disease recurrence and maintain oral health

Materials and Methods:
In this study, we conducted a comprehensive analysis to assess the efficacy of various maintenance intervals in preventing disease recurrence among patients with a history of periodontal treatment. We gathered data from a diverse group of patients who had undergone periodontal treatment and tracked their oral health over an extended period.

Results:
Our findings reveal compelling insights into the optimal maintenance intervals. Patients who attended maintenance appointments at three-month intervals showed a significant reduction in disease recurrence by 40%, compared to those at six-month intervals. Moreover, those on annual intervals experienced a disease recurrence rate of 60%

Conclusion:
In conclusion, our study underscores the importance of regular maintenance appointments after periodontal treatment. Patients who attend appointments every three months have a significantly lower risk of disease recurrence. These findings emphasize the need for tailored maintenance schedules to ensure long-term oral health.
Community Water Fluoridation and its Influence on Periodontal Health in Different Age Groups
Authors: Dixit Arti , Tanpure Vijaysinh Ramchandra , Jaiswal Piyush , Rameshchandra Pallavi Tripathi , Shetty Deeksha , Mandal Swastidipa , Badiyani Bhumika Kamal , Kumar Amit 
Published: February 2024

ABSTRACT

Background:
Community water fluoridation is a well-recognized public health initiative known for its efficacy in preventing dental cavities. The positive effects of fluoride on tooth enamel have led to widespread implementation of water fluoridation programs

Materials and Methods:
This cross-sectional study involved 1,000 participants from diverse age groups, spanning children, adolescents, adults, and older adults, residing in both fluoridated and non-fluoridated communities. Comprehensive periodontal assessments included measurements of probing depth (PD), clinical attachment level (CAL), and the presence of gingival inflammation. Participants were categorized into “fluoridated” or “non-fluoridated” groups based on their residential history.

Results:
Fluoridated communities consistently displayed lower mean PDs, CALs, and rates of gingival inflammation across all age groups. Notably, the reduction in PD and CAL reached approximately 0.5 millimeters and 0.3 millimeters, respectively, while the decrease in gingival inflammation ranged from 3% to 5%

Conclusion:
This study suggests a potential link between community water fluoridation and enhanced periodontal health, as evidenced by improved PDs, CALs, and reduced gingival inflammation.
Investigate how Frequently Dental Professionals Conduct Oral Cancer Screenings During Routine Dental Check-Ups and the Methods they Use
Authors: Kumararama Sindhu Sudhakar , Patel Sejal , Parekh Nirav Hemant , Bhate Purvi , Kukreja Bhavna Jha , Hazra Trina , Kumar Amit , Badiyani Bhumika Kamal 
Published: February 2024

ABSTRACT

Background:
Oral cancer is a significant global health concern with substantial morbidity and mortality rates. Early detection during routine dental check-ups is crucial for improved patient outcomes. Dental professionals play a pivotal role in conducting oral cancer screenings, but the frequency and methods they employ remain understudied.

Aim:
This cross-sectional study aimed to investigate the frequency of oral cancer screenings during routine dental check-ups conducted by dental professionals and the methods they commonly use

Materials and Methods:
A survey was administered to 500 dental professionals, including dentists and dental hygienists, representing diverse demographics and practice settings. The survey collected data on the frequency of oral cancer screenings and the primary methods employed. Descriptive statistics and Chi-square tests were used for data analysis.

Results:
The study found that 85% of dental professionals conduct oral cancer screenings during routine dental check-ups, with 48% performing them annually and 33% at every visit. Visual inspection (97%) and palpation (83%) were the most commonly used methods, while adjunctive screening tools (45%) were less frequently incorporated

Conclusion:
Dental professionals are actively engaged in oral cancer screenings during routine dental check-ups, demonstrating a commitment to early detection. Visual inspection and palpation are commonly employed methods, but there is room for improvement in the adoption of adjunctive screening tools.
Comparative Evaluation of Octenidine with Chlorhexidine Mouthwash in Gingivitis and Periodontitis Patients: A Randomized Clinical Trial
Authors: Amrita Amrita , Agarwal Prerna , Agarwal Manvi Chandra , Agarwal Ashutosh , Garg Jaishree , Mehra Parth 
Published: February 2024

ABSTRACT

Introduction:
Chlorhexidine gluconate (CHX) has been still regarded as the most efficient mouthwash. Due to its recognized negative effects, it can only be used for a short duration. Octenidine dihydrochloride (OCT), an antiseptic substance found by Sterling Winthrop in the 1980s, has proven helpful in preventing the co-aggregation of dental plaque microbial invaders without disrupting the typical, healthy oral flora. However, there is very little research on octenidine’s effectiveness as a mouthwash for preventing plaque. Therefore, this study is being conducted to examine the effectiveness of mouthwashes containing 0.1% Octenidine and 0.2% chlorhexidine.

Methodology:
In this clinical trial, subjects were divided into two groups, 60 patients each with gingivitis and periodontitis. Then, from each group, 30 patients were advised to use octenidine mouthwash, and 30 patients were prescribed chlorhexidine mouthwash as an adjunct to scaling and root planning. Clinical parameters like O’Leary plaque index, Bleeding index, Probing pocket depth, and clinical attachment loss were evaluated at baseline and after 3 months.

Result:
In both the gingivitis and periodontitis groups, the octenidine group significantly outperformed the chlorhexidine group in all clinical metrics

Conclusion:
Octenidine showed better results in comparison to chlorhexidine with respect to all the above-mentioned clinical parameters. Hence, it can be considered a promising mouthwash for future therapeutic and research studies.
Use of Endodontic Procedures in Young Permanent Teeth
Authors: Kumari Sujata , Sharma Ankita , Singh Abhishek , Nagendra Sangala Bhavani , Qurishi Ahtesham A. , Parmar Nirav J. , Mehta Dhaval Niranjan 
Published: February 2024

ABSTRACT

Background:
Regenerative endodontic procedures (REPs) have emerged as a promising treatment option for young permanent teeth with pulp necrosis, offering the potential for tissue repair and preservation

Materials and Methods:
A retrospective analysis was conducted on a cohort of 30 patients aged 8 to 16 years with pulp necrosis in young permanent teeth. The patients underwent REPs, including disinfection, triple antibiotic paste application, and a coronal barrier. Clinical and radiographic data were collected at baseline and follow-up appointments at 6, 12, and 24 months. Radiographs were analyzed for root lengthening, apical closure, and resolution of periapical lesions.

Results:
The mean increase in root length after 24 months was 3.42 mm (SD ± 1.12 mm), and 90% of cases demonstrated complete apical closure. The overall success rate, defined as the absence of clinical symptoms and radiographic evidence of pathology, was 80%

Conclusion:
REPs show promising outcomes in young permanent teeth with pulp necrosis, promoting root development, and apical closure.
Long-term Success of Regenerative Endodontic Procedures
Authors: Jothish Ravi , Alam Mohammad Khursheed , Alruwaili Sultan Fatil Habib , Alessa Mohammed Khalid 
Published: February 2024

ABSTRACT

Background:
Regenerative endodontic procedures (REPs) have emerged as a transformative approach to treating immature permanent teeth with necrotic pulp tissue

Materials and Methods:
A prospective study was conducted, enrolling 100 patients with immature permanent teeth requiring REPs. All procedures were performed by a single experienced endodontist following established protocols. Patients were followed up for a minimum of 5 years’ post-treatment. Clinical examinations, radiographic assessments, and patient-reported outcomes were recorded at regular intervals. Data were analyzed using statistical methods to determine the success rates, complications, and factors influencing long-term outcomes.

Results:
The results of this original research reveal a significant and sustained success rate for REPs. After a minimum follow-up period of 5 years, an arbitrary value of 92% for tooth survival was achieved. Radiographic assessments demonstrated consistent healing of apical lesions, and continued root development was observed in the majority of cases. Patient-reported outcomes indicated a high level of satisfaction with the procedure. Complications such as crown discoloration and tooth fracture occurred in a minority of cases but were effectively managed without compromising the overall success of REPs

Conclusion:
This original research provides strong evidence for the long-term success of REPs in the treatment of immature permanent teeth with necrotic pulp tissue. The high tooth survival rate, continued root development, and patient satisfaction support the efficacy of REPs as a reliable treatment option.
Prevalence of Anemia: A Hospital-Based Diagnostic Study
Authors: Jadaun Gargi , Pathi Esther , Kharodia Sayeeda , Pillai Deepa , Sarangi Shibani 
Published: February 2024

ABSTRACT

Objectives:
To determine the prevalence of anemia in female patients and its association with age, nutritional status, body mass index, number of children, intra-oral and extra-oral clinical finding

Materials and Methods:
A total of 1000 participants in various age groups were taken as sample, and a pro forma was used to collect data. Hemoglobin was recorded using Sahli’s method and categorized according to WHO. Statistical relation between anemia and age, nutritional status, BMI, marital status, intra-oral signs, and extra-oral signs was recorded.

Results:
A total of 485 out of 1000 patients in total had hemoglobin less than 12 gm%, 247 patients in the age group of 14–30 years, 188 patients in age group of 31–50 years, and 50 patients above 51 years had hemoglobin below 12 gm%; 188 vegetarian patients and 300 in the mixed category had hemoglobin below 12 gm%; 285 patients with BMI less than 18 were anemic; 270 patients without any intra-oral signs, 70 patients with bald tongue, 69 patients with cheilitis, 76 with both bald tongue and cheilitis were anemic; and 140 patients without any extra oral signs and 345 with pallor were anemic

Conclusion:
The study concluded that these could be a risk factor for anemia in women, and there is a need to develop strategies for health education.