bluuebunny/crossref_metadata_2025_split huggingface dataset:
Prognostic factors for tumor remission and survival in dogs after surgery for primary lung tumor: 76 cases (1975-1985)
Authors: Ogilvie Gregory K. , Weigel Ronald M. , Haschek Wanda M. , Withrow Stephen J. , Richardson Ralph C. , Harvey H. J. , Henderson Ralph A. , Fowler J. D. , Norris A. M. , Tomlinson J. , McCaw Dudley , Klausner J. S. , Reschke Robert W. , McKiernan Brendan C. 
Published: February 2025

SUMMARY
The association of various prognostic factors with remission and survival after the excision of lung tumors was evaluated in 76 dogs. Overall, the median survival time of treated dogs was 120 days; 72% had tumor that underwent remission (median duration of remission, 120 days). Dogs with tumors that underwent remission had significantly (P = 0.001) increased survival time (median, 330 days vs 28 days for dogs with tumors that did not undergo remission). The finding of normal-sized lymph nodes at the time of therapeutic thoracotomy was significantly (P = 0.001) correlated with increased remission probability (85.4% remission rate vs 43.6% in dogs with large lymph nodes). Use of various diagnostic methods to find normal regional lymph nodes before surgery indicated that such finding was significantly (P ≤ 0.01) correlated with increased remission duration (median remission duration, 365 days, vs 60 days for tumors in dogs with large lymph nodes), and the finding of normal lymph nodes at the time of surgery was significantly (P ≤ 0.01) correlated with increased survival time (median, 345 days, vs 60 days for dogs with large lymph nodes).
Atresia coli in calves: 26 cases (1977-1987)
Authors: Constable Peter D. , Rings D. Michael , Hull Bruce L. , Hoffsis Glen F. , Robertson James T. 
Published: February 2025

SUMMARY
Atresia coli was identified in 26 calves. In calves with abdominal distension, progressive depression, and the absence of feces since birth, atresia coli should be suspected.
Surgery was performed on 24 calves, involving decompression of the distended large intestine followed by colonic anastomosis. Nine calves were subsequently discharged; 3 of those calves reached breeding age. As an adult, 1 of the calves produced 5 offspring unaffected by atresia coli. Early postoperative mortality was associated with hypothermia, peritonitis, and ischemic necrosis of the large intestine. Calves with visible signs of peritonitis at surgery had a poor prognosis. Four calves had motility disturbances of the colon after surgery. These were characteristic of a functional obstruction and were unresponsive to treatment. Surgery was most successful in calves that were bright, alert, and ambulatory.
Clinical, ultrasonographic, and surgical findings in foals with umbilical remnant infections
Authors: Reef Virginia B. , Collatos Chrysann , Spencer Pamela A. , Orsini James A. , Sepesy Lisa M. 
Published: February 2025

SUMMARY
Infection of umbilical arteries, umbilical vein, and/or urachus was diagnosed ultrasonographically in 33 foals 1 to 90 days old (mean, 17.7 ± 17.3 days). In these foals, the most common initial problems were umbilical abnormalities, septic arthritis, and/or neonatal septicemia.
In 16 foals, abnormalities of the external umbilical stalk were noticed on admission. Abnormalities of the internal umbilical structures were identified when enlargement and echogenic material (fluid and /or gas) were imaged ultrasonographically within these structures. Multiple structures were affected in 23 foals, with the urachus the most commonly affected structure.
Surgical findings confirmed ultrasonographic identification of infected umbilical structures in 23 foals. Twenty-two samples from affected umbilical remnants submitted for culture at surgery were positive for bacterial growth. Multiple organisms were isolated in 15 cultures. Escherichia coli and β-hemolytic streptococci were the most common isolates. Two foals died of late complications associated with surgical resection, 1 foal treated surgically and 3 foals treated medically died or were euthanatized because of other complications, and the remaining 27 foals lived.
4-Methylpyrazole as treatment for naturally acquired ethylene glycol intoxication in dogs
Authors: Dial Sharon M. , Thrall Mary Anna , Hamar Dwayne W. 
Published: February 2025

SUMMARY
Eight dogs with ethylene glycol intoxication were treated with 4-methylpyrazole, an alcohol dehydrogenase inhibitor. Dogs had clinical signs referable to ethylene glycol ingestion including ataxia, depression, vomiting, polyuria, and dehydration. Metabolic abnormalities included high anion gap metabolic acidosis, serum hyperosmolality, isosthenuria, and monohydrate and dihydrate calcium oxalate crystalluria. Serum and urine ethylene glycol concentrations were determined to confirm ingestion of ethylene glycol. A 50-mg/ml solution of 4-methylpyrazole in propylene glycol was administered iv as follows: initial treatment, 20 mg/kg of body weight; at 17 hours after admission, 15 mg/kg; at 25 hours after admission, 5 mg/kg. By 24 hours after admission, all dogs had clinical and metabolic improvement. Of the 8 dogs, 7 were released within 3 days of admission. Four of the 8 dogs returned for follow-up evaluation, at which time biochemical or hematologic abnormalities were not observed.
Use of the partial farm budget technique to predict the economic impact of the flock management decision to use B-mode ultrasonographic pregnancy diagnosis
Authors: Sprecher D. J. , Ley W. B. , Whittier W. D. , Bowen J. M. , Thatcher C. D. , Pelzer K. D. , Moore J. M. 
Published: February 2025

Summary
A computer spreadsheet was developed to predict the economic impact of a management decision to use B-mode ultrasonographic ovine pregnancy diagnosis. The spreadsheet design and spreadsheet cell formulas are provided. The program used the partial farm budget technique to calculate net return (nr) or cash flow changes that resulted from the decision to use ultrasonography. Using the program, either simple pregnancy diagnosis or pregnancy diagnosis with the ability to determine singleton or multiple pregnancies may be compared with no flock ultrasonographic pregnancy diagnosis. A wide range of user-selected regional variables are used to calculate the cash flow changes associated with the ultrasonography decisions. A variable may be altered through a range of values to conduct a sensitivity analysis of predicted nr.
Example sensitivity analyses are included for flock conception rate, veterinary ultrasound fee, and the price of corn. Variables that influence the number of cull animals and the cost of ultrasonography have the greatest impact on predicted nr. Because the determination of singleton or multiple pregnancies is more time consuming, its economic practicality in comparison with simple pregnancy diagnosis is questionable. The value of feed saved by identifying and separately feeding ewes with singleton pregnancies is not offset by the increased ultrasonography cost.
Risk factors for lower respiratory tract disease in a cohort of feedlot cattle
Authors: Alexander B. H. , MacVean D. W. , Salman M. D. 
Published: February 2025

Summary
Using data collected from company lot records, potential risk factors related to feedlot management, the cattle, and climate were determined. The risk factors were analyzed by use of weighted multiple regression techniques to determine their effects on the incidence of lower respiratory tract disease in a cohort of 95 lots containing 17,696 cattle. The gender of the cattle, the number of days that groups of cattle filled a lot, pregnancy checking of heifers, and the average temperature change in the first 14 days in which the cattle were on feed significantly influenced the incidence of lower respiratory disease. The incidence of lower respiratory tract disease was most influenced by risk factors in the first 30 days on feed.
Neurologic abnormalities as the predominant signs of neoplasia of the nasal cavity in dogs and cats: Seven cases (1973-1986)
Authors: Smith Mary O. , Turrel Jane M. , Bailey Cleta Sue , Cain Gary R. 
Published: February 2025

Summary
Neurologic abnormalities were the predominant historic and physical findings in 5 dogs and 2 cats with primary nasal cavity tumors that had invaded the cranial vault. Seizures, behavior changes, and obtundation were the most common signs. Other neurologic signs included paresis, ataxia, circling, visual deficit, and proprioceptive deficit. Although 1 dog and 2 cats had historic findings of mild respiratory disease, no physical abnormalities related to the respiratory tract were found in any of the 7 animals. Nasal cavity neoplasia was suggested by radiographic and computed tomographic studies and was confirmed histopathologically in each case. The nasal tumor types in the 5 dogs were epidermoid carcinoma (n = 1), adenocarcinoma (n = 2), solid carcinoma (n = 1), and anaplastic chondrosarcoma (n = 1). An esthesioneuroblastoma was found in each cat. Radiation therapy was effective for 3 months in palliating the clinical signs in the 2 dogs in which it was used. Neoplasia of the nasal cavity should be considered in the differential diagnosis for animals with neurologic signs suggestive of cerebral disorders.
Effect of gonadotropin-releasing hormone on clinical response and fertility in cows with cystic ovaries, as related to milk progesterone concentration and days after parturition
Authors: Dinsmore R. Page , White Maurice E. , Guard Charles L. , Jasko David J. , Perdrizet John A. , Powers Pamela M. , Smith Mary C. 
Published: February 2025

Summary
We gave gonadotropin-releasing hormone (GnRH) or an analog of GnRH to 264 lactating cows with cystic ovaries. The effects of milk progesterone concentration (mpc) and days after parturition (dap) at diagnosis on clinical response 30 days after treatment and on subsequent fertility were examined. Palpation per rectum revealed ovarian cysts in 264 cows; 118 had true follicular cysts (mpc < 1 ng/ml). Clinicians with more than 3 years of experience reported significantly more true cysts than did less experienced clinicians. Clinical response 30 days after treatment did not differ in 3 groups of cows (divided on the basis of mpc at treatment), but fewer cows with mpc <1 ng/ml were bred or conceived than were cows with mpc ≥33 ng/ml. Days after parturition at diagnosis did not affect 30-day clinical response rate, but cows treated <35 dap had significantly more days to first estrus and to conception than did cows treated >90 dap. Significantly more cows treated <35 dap had mpc <1 ng/ml at treatment.
Nosocomial diarrhea associated with enterotoxigenic Clostridium perfringens infection in dogs
Authors: Kruth Stephen A. , Prescott John F. , Welch M. Katharine , Brodsky Michael H. 
Published: February 2025

Summary
A retrospective analysis of the medical records of 30 consecutive cases of diarrhea occurring in dogs that were hospitalized in a teaching hospital was performed. A prospective analysis of culture results for Clostridium perfringens of dogs with diarrhea were compared with those of a control nondiarrheal group.
Hospital-acquired diarrhea in dogs was found to be associated with multiple serotypes of enterotoxigenic Clostridium perfringens. Other potential etiologic agents could not be isolated.
Clinical signs were variable, and included mild depression, anorexia, and soft to watery diarrhea with or without frank blood, mucus, and tenesmus. Fever was not present. There were no hematologic or serum biochemical abnormalities, nor were there any consistent virologic or parasitologic findings. Salmonella spp or Campylobacter spp were not identified by fecal culture. No risk factors could be identified. A dog that was euthanatized on the day it developed diarrhea had intestinal histologic findings suggestive of clostridial enteritis.
Dogs with diarrhea had significantly higher fecal clostridial counts than did dogs without diarrhea (mean log10 counts ± sd = 6.34 ± 1.79 vs 4.75 ± 2.07). Enterotoxin was found in the feces of 41% of diarrheic dogs but in only 7% of dogs without diarrhea.
Thoracic neoplasia in equids: 35 cases (1967-1987)
Authors: Sweeney Corinne Raphel , Gillette Deborah M. 
Published: February 2025

Summary
Thirty-two horses and 3 ponies had neoplasia involving the thoracic cavity. Lymphosarcoma of the thorax was found in 19 (54.2%) of the equids.
The other 16 equids had metastatic adenocarcinoma (7 horses; 20%), metastatic squamous cell carcinoma (5 equids; 14.3%), metastatic hemangiosarcoma (3 equids; 8.6%) or undifferentiated sarcoma (1 horse; 2.9%). Thoracic neoplasia was diagnosed before death in 15 equids (42.9%).
AVMA guide for veterinary medical waste management
Authors: Brody Marcia D. , Markland Moreland Sue 
Published: February 2025

Summary
Lawmakers have enacted a variety of laws and regulations to ensure proper disposal of certain potentially infectious or otherwise objectionable waste. The veterinary medical profession supports scientifically based regulations that benefit public health. In 1988, Congress passed the Medical Waste Tracking Act, a federal program that mandates tracking certain regulated waste.
Several types of waste generated in the typical clinical veterinary medical practice are considered regulated veterinary medical waste. Discarded needles, syringes, and other sharps; vaccines and vials that contained certain live or attenuated vaccines; cultures and stocks of infectious agents and culture plates; research animals that were exposed to agents that are infectious to human beings and their associated waste; and other animal waste that is known to be potentially harmful to human beings should be handled as regulated veterinary medical waste.
Regulated veterinary medical waste should be handled with care. It should be decontaminated prior to disposal. The most popular, effective methods of decontamination are steam sterilization (autoclaving) and incineration. Chemical decontamination is appropriate for certain liquid waste, Waste should be packaged so that it does not spill. Sharps require rigid puncture- and leak-resistant containers that can be permanently sealed. Regulated veterinary medical waste that has not been decontaminated should be labeled with the universal biohazard symbol.
Generators retain liability for waste throughout the entire disposal process. Therefore, it is essential to ensure that waste transporters and disposal facilities comply with state and federal requirements. Veterinary practices should maintain a written waste management program and accurate records of regulated veterinary medical waste disposal. Contingency planning and staff training are other important elements of a veterinary medical waste management program.
The guide includes a model veterinary medical waste management program; however, it does not address all the variations in state and local regulations, Veterinarians should obtain copies of state and local laws and regulations and modify AVMA's model plan to create an individualized practice plan that complies with federal, state, and local laws and regulations, State and local veterinary medical organizations should monitor state and local regulation to influence decisions that affect veterinarians and to keep their members informed of changing requirements, Veterinarians and veterinary medical organizations must stay involved so that regulations do not unfairly burden the veterinary medical profession.
Clinical signs associated with pseudorabies in dogs
Authors: Monroe William E. 
Published: February 2025

SUMMARY
Clinical signs in dogs with pseudorabies (Aujeszky's disease) were tabulated from 25 confirmed cases. The duration of disease was short, ranging from 6 to 96 hours. Eight dogs were euthanatized. Of those not euthanatized, 12 (71%) died within 24 hours of onset, 16 (94%) died within 48 hours, and only 1 (6%) lived longer than 48 hours (96 hours) after the onset of clinical signs. All of the dogs had ptyalism, 84% were restless, 84% were anorectic, 76% were atactic, and 64% wandered aimlessly. Sixty-four percent of the dogs had tachypnea, 60% had dyspnea, 56% vocalized, 52% were pruritic, 48% held their necks rigidly, 36% vomited, 36% had muscle spasms, 36% were aggressive, 28% had trismus, and 24% had dysphagia. Five of 25 dogs (20%) had abnormal pupillary light responses. Two of the 25 dogs circled and 2 walked backwards. Each of the following were detected once: blindness, ptosis, facial paresis, excessive lacrimation, head-tilt, head-pressing, signs of abdominal pain, and photophobia. All dogs had been exposed to swine, although in some instances the farmer was unaware pseudorabies existed in the herd or believed it was not in the herd on the basis of negative results on serologic testing.
Field trial of theophylline in cattle with respiratory tract disease
Authors: McKenna D. J. , Koritz G. D. , Neff-Davis C. A. , Langston V. C. , Berger L. L. 
Published: February 2025

SUMMARY
A field trial was conducted to determine the efficacy of theophylline in relieving respiratory distress associated with bovine respiratory disease complex (shipping fever). Theophylline (as aminophylline capsules) was administered po at a dosage of 28 mg/kg of body weight daily for 3 days to 20 calves with naturally acquired disease. Twenty similarly affected calves from the same group were given a placebo, and all calves were administered antibiotics concurrently. Respiratory rate and rectal temperature decreased and physical appearance improved in both groups of calves and was attributed to antibiotic administration or to natural remission of the disease. Five of the calves administered theophylline died; however, no calves administered the placebo died. Plasma theophylline concentration was greatly increased, compared with that determined in clinically normal calves in a pilot study. Bovine respiratory tract disease and/or concurrent antibiotic administration appear to cause such a rapid accumulation of lethal concentration of theophylline that its use should be restricted to hospitals capable of monitoring plasma theophylline concentration.
Clinical, radiographic, pathologic, and genetic features of osteochondrodysplasia in Scottish Deerhounds
Authors: Breur G. J. , Zerbe C. A. , Slocombe R. F. , Padgett G. A. , Braden T. D. 
Published: February 2025

SUMMARY
Clinical, radiographic, pathologic, and genetic features of a form of osteochondrodysplasia in 5 related Scottish Deerhound pups from 2 litters were evaluated. All pups appeared to be phenotypically normal at birth. At approximately 4 or 5 weeks, exercise intolerance and retarded growth were observed. Kyphosis, limb deformities, and joint laxity gradually developed. Radiography of the affected pups revealed skeletal changes characterized by abnormalities in long bones and vertebrae, with involvement of epiphyses, growth plates, and metaphyses. Short long bones and vertebrae and irregular and delayed epiphyseal ossification were most noticeable in younger pups; in older pups, bony deformities became more prominent. In skeletally mature dogs, osteopenia and severe deformities were seen. The histologic changes of the growth plate were compatible with a diagnosis of chondrodysplasia. Growth plate chondrocytes contained periodic acid Schiff-positive, diastase-resistant cytoplasmic inclusions. A single autosomal recessive mode of inheritance was suspected.
Factors affecting incisional complication rates associated with colic surgery in horses: 78 cases (1983-1985)
Authors: Kobluk Calvin N. , Ducharme Normand G. , Lumsden J.H. , Pascoe Peter J. , Livesey Michael A. , Hurtig Mark , Horney F.D. , Arighi Mimi 
Published: February 2025

SUMMARY
From May 1, 1983 to April 1, 1985, 142 operations were performed on horses with signs of acute abdominal pain (colic), using a ventral midline incision. Seventy-eight horses lived for at least 15 days after surgery or had acute dehiscence and were included in the study. Seventy horses had surgery once, and 8 horses had surgery 2 or more times. Six-month follow-up evaluation was obtained for 66 horses that had 1 surgery and for 6 horses that had multiple surgeries. Incisional complications included drainage (including infection), acute dehiscence, hernia, and suture sinus formation. The effects of preoperative peritoneal fluid presence, enterotomy or resection, suture material and pattern used in the linea alba, type of skin closure and use of a sutured-on stent bandage on the incidence of incisional complications were investigated. The complication of incisional infection rate associated with a near-far-far-near suture pattern vs simple interrupted pattern in the linea alba was the only statistically significant (P < 0.05) difference observed.
Patterns of ionizing radiation exposure among women veterinarians
Authors: Moritz Sheryl A. , Hueston William D. , Wilkins John R. 
Published: February 2025

Summary
Radiation detection devices (film badges) were distributed to a random sample of 118 women in Ohio, Indiana, and Michigan, who had graduated from a US veterinary school between 1970 and 1980, inclusive. Ionizing radiation exposure exceeded 15 mrem/mo in 17% of the women monitored. The maximal recorded whole-body dose was 44.2 mrem/quarter-year, which was well below the maximal permissible doses of 1,250 mrem/quarter-year for nonpregnant women and 500 mrem/quarter-year for pregnant women. Associations between the women's safety beliefs or behaviors and recorded exposure were not observed; however, the school from which the women graduated was an important determinant of safety behavior.
False-positive reactions associated with anti-mouse activity in serotests for feline leukemia virus antigen
Authors: Lopez Noel A. , Jacobson Richard H. 
Published: February 2025

Summary
False-positive reactions were observed in commercial test kits designed to detect FeLV infections in cats. The false-positive reactions were associated with heterophilic antibody in cat serum directed primarily against mouse immunoglobulins. Of 2,830 sera tested, 579 were considered FeLV positive or equivocal via elisa; of these, 10 were found that did not have FeLV antigen but did have anti-mouse antibody. With 95% confidence, 0.14% to 0.57% of cats would have such false-positive reactions in elisa, because one in 283 (0.35%) cats had anti-mouse antibodies.
Sensitivity and specificity of blood test kits for feline leukemia virus antigen
Authors: Lopez Noel A. , Jacobson Richard H. , Scarlett Janet M. , Center Sharon A. , Randolph John F. , Scott Fredric W. 
Published: February 2025

Summary
Enzyme-linked immunosorbent assay (elisa) test kits have been used widely to diagnose FeLV infection. Several companies have licensed such kits, but because these test kits are designed somewhat difjerently, a demonstration of their relative merits was needed. Differences in the sensitivity and specificity of 7 commercial test kits were determined by testing sera that induce false-negative (limiting dilution of FeLV group specific antigen, p27), and false-positive (cat anti-mouse antibody) test results. Among the panels of sera used in this study, Significant differences in test kit sensitivity were not observed, but differences in specificity were identified. An interim report of these studies, supplied to the manufacturers, prompted changes in some of the kits, resulting in improved specificities. Generally, FeLV test kits are now more efficient in accurately detecting p27 in blood, serum, or plasma of cats. Nevertheless, some kits still lack specificity attributable to reagents supplied by the manufacturer.