bluuebunny/crossref_metadata_2025_split huggingface dataset:
SABERES DE CURA E DE SAÚDE NO ÂMBITO DA GEOGRAFIA: HERANÇA COLONIAL NO BRASIL
Authors: Bastos Carla Alessandra Melo de Freitas , Pinto Josefa Eliane Santana de Siqueira 
Published: February 2024

Desde os primórdios, o temor à ocorrência das doenças, bem como a busca de suas possíveis causas e procedimentos curativos, fazem parte das preocupações humanas. Assim, a sociedade passou a construir diferentes interpretações na tentativa de compreender e explicar o processo saúde-doença. A construção e entendimento dos conceitos de saúde e doença dependem de um dado contexto, que leva em consideração diversos elementos que permeiam uma sociedade. Destarte, com intuito de fomentar uma reflexão acerca do cuidado com a saúde, no âmbito da formação do território brasileiro, o presente artigo busca analisar as múltiplas representações e conexões de costumes, saberes, práticas, crenças, partilhadas entre as três culturas – a indígena, a europeia e a africana -, com intuito de compreender, ao longo do tempo, a importância e construção da arte de cura. Realizaram-se pesquisas bibliográficas com intuito de resgatar tais saberes, partindo da herança colonial, tendo em vista que perduram e resistem ao tempo. Os vínculos entre a Geografia e as condições do processo saúde-doença são numerosos, circundando aspectos históricos, sociais, ambientais, biológicos, políticos, comportamentais e culturais. Contudo, nota-se, no âmbito da Geografia da saúde, certa carência quanto se trata de escritos relacionados a alternatividades a saúde.
HbA1c and fasting plasma glucose levels are equally related to incident cardiovascular risk in a high CVD risk population without known diabetes
Authors: Been Riemer A. , Noordstar Ellen , Helmink Marga A.G. , van Sloten Thomas T. , de Ranitz-Greven Wendela L. , van Beek André P. , Houweling Sebastiaan T. , van Dijk Peter R. , Westerink Jan 
Published: February 2024

Abstract

Objectives
Type 2 diabetes (T2DM) is associated with increased risk for cardiovascular disease (CVD). Whether screen-detected T2DM, based on fasting plasma glucose (FPG) or on HbA1c, are associated with different risks of incident CVD in high-risk populations and which one is preferable for diabetes screening in these populations, remains unclear.

Methods
A total of 8,274 high-risk CVD participants were included from the UCC-SMART cohort. Participants were divided into groups based on prior T2DM diagnosis, and combinations of elevated/non-elevated FPG and HbA1c (cut-offs at 7 mmol/L and 48 mmol/mol, respectively): Group 0: known T2DM; group 1: elevated FPG/HbA1c; group 2: elevated FPG, non-elevated HbA1c; group 3: non-elevated FPG, elevated HbA1c; group 1 + 2: elevated FPG, regardless of HbA1c; group 1 + 3: elevated HbA1c, regardless of FPG; and group 4 (reference), non-elevated FPG/HbA1c.

Results
During a median follow-up of 6.3 years (IQR 3.3–9.8), 712 cardiovascular events occurred. Compared to the reference (group 4), group 0 was at increased risk (HR 1.40; 95 % CI 1.16–1.68), but group 1 (HR 1.16; 95 % CI 0.62–2.18), 2 (HR 1.18; 95 % CI 0.84–1.67), 3 (HR 0.61; 95 % CI 0.15–2.44), 1 + 2 (HR 1.17; 95 % CI 0.86–1.59) and 1 + 3 (HR 1.01; 95 % CI 0.57–1.79) were not. However, spline interpolation showed a linearly increasing risk with increasing HbA1c/FPG, but did not allow for identification of other cut-off points.

Conclusions
Based on current cut-offs, FPG and HbA1c at screening were equally related to incident CVD in high-risk populations without known T2DM. Hence, neither FPG, nor HbA1c, is preferential for diabetes screening in this population with respect to risk of incident CVD.
The origin of {113}<361> grains and their impact on secondary recrystallization in producing ultra-thin grain-oriented electrical steel
Authors: Liang Ruiyang , Li Qingchun , Ling Shuo 
Published: February 2024

Abstract
Ultra-thin grain-oriented electrical steel with a thickness of 80 µm is produced by one-step-rolling with industrial grain-oriented electrical steel. The research employs electron back-scattering texture analysis technique to investigate the evolution of deformation and recrystallization textures in this specific steel. Emphasis is placed on examining the origin of {113}<361> grains and their consequential impact on secondary recrystallization. It is revealed that primary, secondary, and tertiary recrystallization phases are integral during the annealing process. The origin of surface {113}<361> grains were result of initial deviated Goss grains with specific shear deformation behavior in cold rolled ultra-thin strips. Additionally, the influence of these grains on texture evolution is predominantly evident during secondary recrystallization. These grains potentially undergo abnormal growth in secondary recrystallization, exploiting high-energy grain boundaries among Goss grains. This phenomenon consequently leads to the diminution of the sharp Goss texture formed during primary recrystallization. Given the magnetic properties and predominant applications of ultra-thin grain-oriented electrical steel in medium-frequency fields, it is recommended to prepare ultra-thin grain-oriented steel during primary recrystallization phase.
Association of tobacco experimentation with anxiety and depression: findings from a representative sample of Tunisian adolescents
Authors: Amara Amel , Omri Nihel , Bannour Rania , Limam Manel , El Ghardallou Meriam , Mellouli Menel , Sahli Jihene , Mtiraoui Ali 
Published: February 2024

Abstract

Objectives
Emerging evidence points to tobacco experimentation being associated with a vast array of mental disorders, particularly anxiety and depression. We aimed to assess the prevalence of tobacco experimentation, its predictive factors and its potential links with anxiety and depressive disorders among in school adolescents in a Tunisian delegation.

Methods
We carried out a cross sectional study among adolescents schooling in middle and high schools in the delegation of Nfidha, Sousse, Tunisia, during the period from January to March of the 2019–2020 school year using an anonymous questionnaire self-administered to a representative sample of 1,353 randomly selected pupils. Data were collected using the Arabic versions of the Beck Depression Inventory short form (13 items) and the Screen for Child Anxiety Related Disorders (SCARED-C) and a socio-demographic questionnaire with reference to the literature.

Results
Tobacco was experimented by (17.5 %; CI 95 %: 14.8–18.8 %) of pupils. Almost three out of four pupils (73.2 %; CI 95 %: 70.8–75.6 %) reported experiencing depressive symptoms and (65 %; CI 95 %: 62.5–67.5 %) anxiety symptoms. Pupils who exhibited depressive disorder indicators were significantly more prone to experiment with tobacco (20.2 vs. 9.9 %, p<0.001; crude OR=2.301 CI 95 %: 1.74–3.58). Similarly, the prevalence of tobacco experimentation was found to be higher among pupils who reported having experienced anxiety disorders (21.0 vs. 14.5 %, p<0.001; crude OR=1.56 CI 95 %: 1.06–2.27). Being a male pupil (AOR=5.48 95 % CI: 3.62–8.31), being be enrolled in a high school (AOR=2.86, 95 % CI: 1.92–4.26), tobacco use by father and siblings (respectively AOR=1.76, 95 % CI: 1.19–2.60; AOR=2.47, 95 % CI: 1.52–4.02) and experiencing depressive disorders (AOR=2.69, 95 % CI: 1.60–4.53) were the determinants of tobacco experimentation in the multivariate analysis.

Conclusions
Tobacco experimentation in adolescence has been shown to be significantly associated with anxiety and depression. National smoking prevention strategies should be reinforced with a focus on mental health disorders.
Feasibility of 3-dimensional printed models in simulated training and teaching of transcatheter aortic valve replacement
Authors: Mao Yu , Liu Yang , Ma Yanyan , Zhai Mengen , Li Lanlan , Jin Ping , Yang Jian 
Published: February 2024

Abstract
In the study of TAVR, 3-dimensional (3D) printed aortic root models and pulsatile simulators were used for simulation training and teaching before procedures. The study was carried out in the following three parts: (1) experts were selected and equally divided into the 3D-printed simulation group and the non-3D-printed simulation group to conduct four times of TAVR, respectively; (2) another 10 experts and 10 young proceduralists were selected to accomplish three times of TAVR simulations; (3) overall, all the doctors were organized to complete a specific questionnaire, to evaluate the training and teaching effect of 3D printed simulations. For the 3D-printed simulation group, six proceduralists had a less crossing-valve time (8.3 ± 2.1 min vs 11.8 ± 2.7 min, P < 0.001) and total operation time (102.7 ± 15.3 min vs 137.7 ± 15.4 min, P < 0.001). In addition, the results showed that the median crossing-valve time and the total time required were significantly reduced in both the expert group and the young proceduralist group (all P<0.001). The results of the questionnaire showed that 3D-printed simulation training could enhance the understanding of anatomical structure and improve technical skills. Overall, cardiovascular 3D printing may play an important role in assisting TAVR, which can shorten the operation time and reduce potential complications.
Effect of struvite on the growth of green beans on Mars and Moon regolith simulants
Authors: Wamelink Wieger , Pouwels Charlotte 
Published: February 2024

Abstract
When humans are going to live on the Moon or Mars, food production and reusing waste products as manure will be essential for their survival. This calls for a circular sustainable agricultural ecosystem for food production. Earlier experiments have shown that crop growth is possible on simulant regoliths though there are several challenges. One of them is the shortage of nitrate or ammonium in the regoliths. Moreover, phosphate is not easily available. This could be solved by the application of human feces as manure. The goal of this experiment was to test if human urine-based struvite (MgNH4PO4) could fertilize Mars and Moon regolith simulants and lead to a higher yield of green beans. Three “soils” were examined: Mars regolith simulant (MMS), Moon regolith simulant (JSC 1A), and Earth potting soil with and without struvite. Forty grams of struvite were added, besides 10% (volume) organic matter. The experiment was conducted in tenfold. Length of plants was recorded, and beans were harvested when ripe and at the end of the experiment, three and a half months after the start. The struvite treatment yielded a significantly higher bean harvest. Plants on potting soil and Moon soil simulant with struvite addition reached the same height and were higher than the control plants. The plants on Mars soil simulant were smaller but still taller than the control. It can be concluded that the addition of struvite had a significant positive effect on the production of green beans on potting soil and Mars and Moon soil simulant.
In vitro antimicrobial and antioxidant activities, essential oil composition, and in silico molecular modeling analysis of secondary metabolites from roots of Verbascum sinaiticum
Authors: Tegegn Getachew , Melaku Yadessa , Aliye Muhdin , Abebe Abiy , Abdissa Negera , Meresa Asfaw , Degu Sileshi , Hunsen Mo , Hussein Ahmed A. , Endale Milkyas 
Published: February 2024

Abstract

Verbascum sinaiticum is locally used to treat wound, stomachache, viral infection, cancer, sunstroke fever, abdominal colic, diarrhea, hemorrhage, anthrax, and hepatitis. The objective of this study was to identify the compounds and to evaluate the antimicrobial and antioxidant activity of the extracts and isolated compounds from V. sinaiticum. The 1H-NMR, 13C-NMR, and DEPT-135 were used to elucidate the structures of isolated compounds. Essential oils were extracted by hydrodistillation method and their chemical analyses were performed by GC-MS. The broth microdilution method was used to evaluate the antimicrobial activity. The radical scavenging activity of the extracts and isolated compounds were evaluated using DPPH method. Silica gel column chromatographic separation of root extracts afforded seven known compounds: 3′-(4′′-methoxy phenyl)-3′-oxo-propionyl hexadecanoate (1), harpagoside (2), pulverulentoside I (3), scrophuloside B4 (4), scropolioside A (5), scropolioside-D2 (6), and harpagide 6-O-β-glucoside (7), which are all reported from this species for the first time. The EO extracts from leaves and roots were the most susceptible to Streptococcus agalactiae, with a 2 mg/mL MIC. The EO from roots was effective against Candida albicans and Trichophyton mentagrophytes, with a MIC of 8 mg/mL. The MeOH and CH2Cl2/CH3OH (1:1) root extracts showed the maximum activity against S. epidermidis with MIC values of 0.25 mg/mL. The strongest antibacterial effects were demonstrated against Staphylococcus epidermidis, which exhibited a 0.0625 mg/mL MIC for compound 1. The strongest radical scavenging activity was exhibited by the methanol extract (IC50 = 3.4 μg/mL), and compounds 4, 6, 5, 3, 7, and 2 with IC50 values of 3.2, 3.38, 3.6, 3.8, 4.2, and 4.7 μg/mL, respectively, in comparison with ascorbic acid (IC50 = 1.3 μg/mL). The results of the molecular docking analysis of compounds revealed minimal binding energies range from −38.5 to −43.1 kJ/mol, −33.1 to −42.7 kJ/mol, −34.7 to −39.3.7 kJ/mol, −25.5 to −37.6 kJ/mol against human myeloperoxidase (PDB ID: 1DNU), murA enzyme (PDB ID: 1UAE), human topoisomerase IIβ (PDB ID: 4fm9), S. epidermidis FtsZ (PDB number: 4M8I) proteins, respectively. The docking results and the in vitro antibacterial activity are in good agreement. These findings show that the isolated compounds 2–7 can act as potential antioxidants and strong antibacterials against Staphylococcus aureus and S. epidermidis. As a result, V. sinaiticum root extracts have the potential to be effective in treating diseases caused by bacteria and free radicals, as long as further investigation has been suggested for the ultimate decision of this plant’s potential candidate.
“Knees Out” or “Knees In”? Volitional Lateral vs. Medial Hip Rotation During Barbell Squats
Authors: Chiu Loren Z.F. 
Published: February 2024

Abstract
Chiu, LZF. “Knees out” or “Knees in”? Volitional lateral versus medial hip rotation during barbell squats. J Strength Cond Res 38(3): 435–443, 2024—Medial or lateral hip rotation may be present during barbell squats, which could affect the hip frontal and transverse plane moments. Male (n = 14) and female (n = 18) subjects performed squats using their normal technique and with volitional medial and lateral hip rotation. Hip net joint moments (NJM) were calculated from 3-dimensional motion capture and force platform measurements. Statistical significance was set for omnibus tests (α = 0.05) and Bonferroni’s corrected for pairwise comparisons (α

t-test = 0.0056). Normal squats required hip extensor, adductor, and lateral rotator NJM. Lateral rotation squats had smaller hip extensor (p = 0.002) and lateral rotator (p < 0.001) NJM and larger hip adductor (p < 0.001) NJM than normal squats. Medial rotation squats had smaller hip extensor (p = 0.002) and adductor (p < 0.001) NJM and larger hip lateral rotator (p < 0.001) NJM than normal squats. These differences exceeded the minimum effects worth detecting. As gluteus maximus exerts hip extensor and lateral rotator moments, and the adductor magnus exerts hip extensor and adductor moments, these muscles combined would be required to meet these hip demands, supporting previous research that has established these muscles as the primary contributors to the hip extensor NJM. Lateral rotation squats reduce hip lateral rotator and increase hip adductor NJM, which may be hypothesized as preferentially loading adductor magnus. Medial rotation squats increase hip lateral rotator and decrease hip adductor NJM; therefore, this variant may shift loading to the gluteus maximus.
The Sensitivity and Specificity of Procalcitonin in Diagnosing Bacterial Sepsis in Neonates
Authors: Beaumont Rachael , Tang Kailey , Gwee Amanda 
Published: February 2024

CONTEXT AND OBJECTIVESNeonatal sepsis accounts for 15% of all neonatal deaths. Early detection enables prompt administration of antibiotic treatment, reducing morbidity and mortality. This study aims to review the sensitivity and specificity of procalcitonin in diagnosing microbiologically-proven sepsis in neonates to determine the optimal procalcitonin cut-off value for use in clinical practice.DATA SOURCES, STUDY SELECTION, AND DATA EXTRACTIONMedline, EMBASE and PubMed were searched on 3 May 2023 for original studies in symptomatic neonates in whom both blood culture and procalcitonin levels were taken, and a procalcitonin cut-off with either sensitivity or specificity reported. Studies that included asymptomatic or culture-negative neonates in the proven sepsis group were excluded. Risk of bias was assessed using the Qualitative Assessment of Diagnostic Accuracy Studies 2 tool.RESULTSNineteen original studies enrolling a total of 1920 symptomatic neonates (721 with proven sepsis) were included. Six studies used a procalcitonin cut-off of 0.5 ng/mL and found a sensitivity of 87% to 100% and specificity of 17% to 89%. Nine studies evaluated higher procalcitonin cut-off values between 0.99 ng/mL and 2 ng/mL, which were 67% to 98% sensitive and 41% to 89% specific. All other procalcitonin thresholds were neither sensitive nor specific. Meta-analysis was not performed because of high risk of bias within the identified studies.CONCLUSIONSThis review found that procalcitonin was highly sensitive (87% to 100%) at a cut-off value of 0.5 ng/mL, although specificity varied greatly across all cut-off values reviewed. The variation in diagnostic accuracy between studies suggests that procalcitonin may be useful to guide antibiotic cessation but should not be used alone as a diagnostic marker for neonatal sepsis.
High-intensity interval training on unstable vs stable surfaces: effects on explosive strength, balance, agility, and Tsukahara vault performance in gymnastics
Authors: Abuwarda Khaled , Mansy Mostafa , Megahed Mohamed 
Published: February 2024

Background and Study Aim. This study compares the effects of high-intensity interval training (HIIT) on unstable and stable surfaces on explosive strength, balance, agility, and Tsukahara vault performance in gymnastics.
Material and Methods. A nonrandomized trial study was conducted on twenty-seven well-trained male vault players who were assigned into 3 equal groups, a HIIT unstable group (UG), a HIIT stable group (SG), and the control group (CG). The training period for the subjects lasted eight weeks, with 3 sessions each week. All of the aforementioned variables were assessed both before and after the training period.
Results. The main findings indicate that both UG and SG showed greater improvement than the CG on explosive strength, balance, agility, and Tsukahara vault performance in gymnastics (ES= 0.52 to 0.68, P<0.05). In addition, there were significant differences between the UG and SG in explosive strength, balance and Tsukahara vault performance (P<0.05) favoring UG, while no significant differences between UG and SG in agility. However, the UG as compared to the SG in agility had only limited additional effects. The UG and SG significantly increased all tests from pre- to post-test (ES= 1.10 to 4.78, 0.98 to 3.53), respectively (P<0.05). The CG significantly increased the explosive strength and Tsukahara vault performance tests from pre- to post-test ((ES= 0.77 to 0.78, P <0.05), while there were no significant differences in the balance and agility tests (P > 0.05).
Conclusions. Accordingly, HIIT with unstable surfaces can be used as an alternative method to improve explosive strength and balance. Also, it can be used alongside stable surface exercises when developing agility.
National theater in the aspect of M. D. Leontovych’s pedagogical activity in Tulchyn
Authors: Gubal Alla 
Published: February 2024

Modern complex socio-economic and cultural processes of development of the country are directed at radical renewal of Ukrainian society. The promising gradual development of the latest currents in the field of primary education in Ukraine has always been an important step for the native music and pedagogical science, because in order to use new technologies in practical activities, scientists need to consider in detail, analyze, systematize and adapt the past pedagogical experience of outstanding Ukrainian teachers-musicians. The problem of using the means of theatrical art in the practice of the modern school, which, according to Leontovych, contributes to the formation of important life values and active aesthetic activity, especially in younger schoolchildren, is topical in today's education.
Turning to the national traditions of the past experience of the theatrical aspect in the pedagogical activity of the teacher M. Leontovych is directed at the spiritual revival of the creative activity of the individual. The essence of the concepts of theatrical art, theatrical activity, theatrical play at school has been clarified; the main types of theatrical performances are given; the most used methods of stage adaptation are considered and the necessity of their use in classes is argued. Thanks to the universalism of the choral theater dramatization method, the teacher revealed the creative inclinations of students in the formation of individuality. Aspects of many creative studies on theatrical pedagogical activities of M. Leontovych require detailed study and innovative approaches in connection with current problems of music pedagogy, musicology, and music folklore.
The use of the aspect of theatrical art in regular music classes had a significant potential for the harmonious aesthetic development, especially of younger schoolchildren. The teacher in practice proved the evolutionary significance of theater and choral pedagogy (which has an analytical and synthetic character) and revealed the possibilities of influencing the emotional and sensory sphere of the student, equating theatrical art to children's play. The highlighted methods of M. Leontovych show that during the play the independent expression of personality is mostly manifested, and with the help of the group nature of theatrical activity, the emotional impact is enhanced, which inextricably goes along with inspiration, joy, and a sense of unity for the sake of a common cause.
Based on the analysis of M. Leontovych's pedagogical activity, it can be determined that the artist stood at the origins of children's theatrical choral art in Podilla at the beginning of the 20th century in the context of socio-cultural integration of Ukraine, but it has been proven a priori that the modern process of education is not yet sufficiently studied and needs further in-depth understanding