bluuebunny/crossref_metadata_2025_split huggingface dataset:
Total Synthesis of Azumamide A (Ia) and Azumamide E (Ib): Evaluation as Histone Deacetylase Inhibitors, and Design of a More Potent Analogue (Ic).
Authors: Wen Shijun , Carey Krystle L. , Nakao Yoichi , Fusetani Nobuhiro , Packham Graham , Ganesan A. 
Published: July 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Practical and Efficient Entry to Isoflavones by Pd(0)/C‐Mediated Suzuki—Miyaura Reaction. Total Synthesis of Geranylated Isoflavones.
Authors: Felpin Francois‐Xavier , Lory Cecile , Sow Hawaa , Acherar Samir 
Published: July 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
An Efficient Synthesis of (+)‐Decursinol from Umbelliferone.
Authors: Lee Jung Ho , Bang Hyun Bae , Han Su Young , Jun Jong‐Gab 
Published: July 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Isolation and Structure Elucidation of a Potent Growth Inhibitor, Helian, from Blue Light‐Illuminated Sunflower (Helianthus annuus) Hypocotyls.
Authors: Hasegawa Tsuyoshi , Togo Shigenori , Hisamatsu Yosuke , Yamada Kosumi , Suenaga Kiyotake , Sekiguchi Mitsuhiro , Shigemori Hideyuki , Hasegawa Koji 
Published: July 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Nitroimidazoles. Part 3. Synthesis and anti‐HIV Activity of New N‐Alkyl‐4‐nitroimidazoles Bearing Benzothiazole and Benzoxazole Backbones.
Authors: Al‐Soud Yaseen A. , Al‐Sa'doni Haitham , Amajaour Houssain A. S. , Al‐Masoudi Najim A. 
Published: July 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Pressure‐ and Field‐Induced Non‐Fermi‐Liquid Behaviors in a Heavy‐Fermion Antiferromagnet Ce7Ni3.
Authors: Umeo K. , Takabatake T. 
Published: July 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Exploring Chemical Space with Organometallics: Ruthenium Complexes as Protein Kinase Inhibitors
Authors: Meggers Eric , Atilla‐Gokcumen G. Ekin , Bregman Howard , Maksimoska Jasna , Mulcahy Seann P. , Pagano Nicholas , Williams Douglas S. 
Published: July 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Recent Advances in Metal‐Catalyzed Asymmetric Conjugate Additions
Authors: Christoffers Jens , Koripelly Girish , Rosiak Anna , Roessle Michael 
Published: July 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Development of Dendrimers: Macromolecules for Use in Organic Light‐Emitting Diodes and Solar Cells
Authors: Lo Shih‐Chun , Burn Paul L. 
Published: July 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Micro‐ and Nanopatterning Techniques for Organic Electronic and Optoelectronic Systems
Authors: Menard Etienne , Meitl Matthew A. , Sun Yugang , Park Jang‐Ung , Shir Daniel Jay‐Lee , Nam Yun‐Suk , Jeon Seokwoo , Rogers John A. 
Published: July 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Highly Efficient Organic Devices Based on Electrically Doped Transport Layers
Authors: Walzer K. , Maennig B. , Pfeiffer M. , Leo K. 
Published: July 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Rh(I)‐Catalyzed Cyclizations via Rhodacycle Intermediates: Application to the Synthesis of (.+‐.)‐Epiglobulol
Authors: Oonishi Yoshihiro , Mori Miwako , Sato Yoshihiro 
Published: July 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Selective Molecular Transformation of 1,2‐Diols Based on Molecular Recognition
Authors: Matsumura Yoshihiro , Onomura Osamu , Demizu Yosuke 
Published: July 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Organotrifluoroborates: Protected Boronic Acids that Expand the Versatility of the Suzuki Coupling Reaction
Authors: Molander Gary A. , Ellis Noel 
Published: July 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Modifications of Aminoglycoside Antibiotics Targeting RNA
Authors: Zhou Jian , Wang Guannan , Zhang Li‐He , Ye Xin‐Shan 
Published: July 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Synthesis of Valiolamine and Some Precursors for Bioactive Carbaglycosylamines from (‐)‐vibo‐Quercitol Produced by Biogenesis of myo‐Inositol
Authors: Ogawa Seiichiro , Kanto Miki 
Published: July 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Synthetic Methods to Incorporate α‐Linked 2‐Amino‐2‐deoxy‐D‐glucopyranoside and 2‐Amino‐2‐deoxy‐D‐galactopyranoside Residues into Glycoconjugate Structures
Authors: Kerns Robert J. , Wei Peng 
Published: July 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Electron Transfer and Structural Change: Distinguishing Concerted and Two‐Step Processes
Authors: Macias‐Ruvalcaba Norma A. , Evans Dennis H. 
Published: July 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Smart Nanomaterials Inspired by Biology: Dynamic Assembly of Error‐Free Nanomaterials in Response to Multiple Chemical and Biological Stimuli
Authors: Lu Yi , Liu Juewen 
Published: July 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Nanoparticle Interaction with Biological Membranes: Does Nanotechnology Present a Janus Face?
Authors: Leroueil Pascale R. , Hong Seungpyo , Mecke Almut , Baker James R. Jr. , Orr Bradford G. , Holl Mark M. Banaszak 
Published: July 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Next Generation, Sequentially Assembled Ultrathin Films: Beyond Electrostatics
Authors: Quinn John F. , Johnston Angus P. R. , Such Georgina K. , Zelikin Alexander N. , Caruso Frank 
Published: July 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Thermodynamics and Mechanisms of the Formation of Supramolecules and Supramolecular Assemblies of s, p, d and f Elements: Problems and Prospects
Authors: Tsivadze A. Yu. , Ionova G. V. , Mikhalko V. K. , Kostrubov Yu. N. 
Published: July 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Structure–Activity Studies on Suramin Analogues as Inhibitors of NAD+‐Dependent Histone Deacetylases (Sirtuins)
Authors: Trapp Johannes , Meier Rene , Hongwiset Darunee , Kassack Matthias U. , Sippl Wolfgang , Jung Manfred 
Published: July 2007

AbstractSuramin is a symmetric polyanionic naphthylurea originally used for the treatment of trypanosomiasis and onchocerciasis. Suramin and diverse analogues exhibit a broad range of biological actions in vitro and in vivo, including, among others, antiproliferative and antiviral activity. Suramin derivatives usually target purinergic binding sites. Class III histone deacetylases (sirtuins) are amidohydrolases that require nicotinamide adenine dinucleotide (NAD+) as a cofactor for their catalytic mechanism. Deacetylation of the target proteins leads to a change in conformation and alters the activity of the proteins in question. Suramin was reported to inhibit human sirtuin 1 (SIRT1). We tested a diverse set of suramin analogues to elucidate the inhibition of the NAD+‐dependent histone deacetylases SIRT1 and SIRT2 and discovered selective inhibitors of human sirtuins with potency in the two‐digit nanomolar range. In addition, the structural requirements for the binding of suramin derivatives to sirtuins were investigated by molecular docking. The recently published X‐ray crystal structure of human SIRT5 in complex with suramin and the human SIRT2 structure were used to analyze the interaction mode of the novel suramin derivatives.
Expanded phase II trial of gemcitabine and capecitabine for advanced biliary cancer
Authors: Riechelmann Rachel P. , Townsley Carol A. , Chin Sheray N. , Pond Gregory R. , Knox Jennifer J. 
Published: July 2007

AbstractBACKGROUND.A phase 2 trial of gemcitabine and capecitabine (GemCap) in patients with advanced biliary cancer led to an objective response in approximately 30% of patients and a median survival of 14 months. In the current study, the authors report further efficacy data of a larger cohort of such patients treated with the GemCap regimen.METHODS.Patients aged >18 years and who had a diagnosis of locally advanced biliary cancer received first‐line treatment with capecitabine at a dose of 650 mg/m2 twice daily for 14 days and gemcitabine at a dose of 1000 mg/m2 on Day 1 and Day 8, every 3 weeks until disease progression. Tumor response was assessed by Response Evaluation Criteria In Solid Tumors (RECIST) criteria.RESULTS.Between July 2001 and January 2005, 75 patients were enrolled in the study. At a median follow‐up of 9.5 months, the overall response rate was 29% (95% confidence interval [95% CI], 19.4–41%), with a median duration of 9.7 months (range, 3–36 months). Three patients achieved complete responses, with a median duration of 17 months (range, 9–27 months). The median progression‐free survival and overall survivals were 6.2 months (95% CI, 4.4–8.3 months) and 12.7 months (95% CI, 9.5–31 months), respectively.CONCLUSIONS.The GemCap regimen is active in patients with biliary cancer. Randomized trials are warranted to define the impact of such a regimen on patient survival and quality of life. Cancer 2007. © 2007 American Cancer Society.
Lightweight emulation to study peer‐to‐peer systems
Authors: Nussbaum Lucas , Richard Olivier 
Published: July 2007

AbstractThe current methods used to test and study peer‐to‐peer systems (namely modeling, simulation or execution on real testbeds) often show limits regarding scalability, realism and accuracy. This paper describes and evaluates P2PLab, our framework to study peer‐to‐peer systems by combining emulation (use of the real studied application within a configured synthetic environment) and virtualization. P2PLab is scalable (it uses a distributed network model) and has good virtualization characteristics (many virtual nodes can be executed on the same physical node by using process‐level virtualization). Experiments with the BitTorrent file‐sharing system complete this article and demonstrate the usefulness of this platform. Copyright © 2007 John Wiley & Sons, Ltd.
Telecommunication system architectures: Dealing with complexity
Authors: van den Dool F. 
Published: July 2007

AbstractThe changing environment of telecommunications service operators leads to an increasing customer orientation and an ever increasing complexity. The technical consequence of the increased customer orientation is visible in the higher interest in flexibility engineering. The increasing complexity is becoming the major problem in telecommunication systems of this decade. To deal with this complexity two fundamental capabilities are used: abstraction and structuring. In general, models can be identified on any level of abstraction, e.g. high‐level system behaviour models, high‐level system architectural models and low‐level architectural models. When system complexity increases, more levels of abstraction will be necessary to deal with this complexity. Various methods exist to define models at different levels of abstraction. In this paper three modelling methods are discussed. It is demonstrated that abstraction is used in a similar way in these modelling methods. One particular method for abstraction is the use of the object‐oriented paradigm, a powerful approach for modelling as well as for implementation. Additional structuring methods based on considerations with respect to the functionality, however, remain indispensable in order to keep complexity under control. Those methods, stratification and segregation, are specifically relevant in high level architectural models.
Maximal connected sets—application to microcell CDMA
Authors: Tirkel A. Z. , Osborne C. F. , Mee N. , Rankin G. A. , McAndrew A. 
Published: July 2007

AbstractCurrent trends in personal and data communication networks favour code division multiple access (CDMA) as a solution to spectral congestion. This is because of enhanced capacity, security, network flexibility, simplified protocol, and relative immunity to propagation induced errors such as multipath and interference, as compared with traditional frequency division multiple access (FDMA). Various CDMA schemes have been proposed and described in relation to VSAT systems, local area microcells,2 and cellular telephones. Additionally, numerous product applications have emerged in the areas of modems, voice links and wireless local exchanges. These systems require inter‐ and intra‐cell control. By contrast, the scheme presented in this paper places no reliance on intercell protocol. It enables new cells to be added to the network without any impact on the hardware. Network reconfiguration requires software changes only. Therefore, the scheme is appropriate to systems which demand flexibility with minimum overheads.
Staggered multicast protocol with collision‐free acknowledgement in multihop spread spectrum packet radio networks
Authors: Hung Kwok‐Wah , Yum Tak‐Shing 
Published: July 2007

AbstractThe staggered multicast protocol for multihop spread spectrum packet radio networks is suitable for unicasting and broadcasting as well as multicasting. The common‐header/transmitter‐based spreading code is used for data packet transmission and the receiver‐based code is used for acknowledgement packet transmission. By staggering packet transmission the protocol can significantly reduce broadcasting delay. A special addressing method and packet format are also designed to achieve collision‐free acknowledgement and multicast capability. Simulation results show that the protocol provides better throughput‐delay performance than the common‐header/transmitter‐based slotted ALOHA protocol.
Object‐oriented analysis of signalling and control in broadband networks
Authors: Veeraraghavan M. , la Porta T. F. 
Published: July 2007

AbstractThis paper analyses the problem of providing call, connection, channel, and service control in broadband and intelligent networks to support a wide variety of services. A formal methodology called object‐oriented analysis (OOA) is used to analyse this problem. Three types of OOA models are constructed: the information model, state models and the object communication model. From these models, a distributed call processing architecture that proposes separate servers for call control, connection control, channel control and service control, is derived. Based on the events used for inter‐object communication in the object communication model, service‐specific and control‐function specific application service elements are defined as client‐server based protocols.
Bursty ATM user traffic allowed by a jitter tolerant leaky bucket and its impact on link utilization
Authors: Heiss Herbert 
Published: July 2007

AbstractIn a network based on the asynchronous transfer mode (ATM), quality of service requirements have to be met even in the presence of users who send traffic as bursty as the policing device allows. For peak cell rate policing with a jitter tolerant leaky bucket, a periodic maximally bursty traffic pattern allowed by the leaky bucket is derived. The impact of this kind of bursty user traffic on the cell loss performance of the remaining sources is investigated by introducing, solving and applying the queueing model Geo(n) + P/D/1/K, where P stands for ‘periodic’. Taking bursty user traffic into account, it is shown that the maximal jitter or cell delay variation allocated to the user and tolerated by the leaky bucket is an important parameter for link utilization. The results help to answer the question under which conditions a shaping function is needed in conjunction with the usage parameter control function.
Influence of sampling period on time and frequency stability measurements
Authors: Carbonelli Marco , de Seta Domenico , Perucchini Daniele , Zampilloni Guido 
Published: July 2007

AbstractBecause of the introduction of SDH based networks, the exigence of performing stability measurements on timing signals is becoming more and more stringent. In this paper, the influence of the measurement sampling period on the behaviour of the stability quantities is analysed and useful information for specification design and assessment purposes are provided.
A performance analysis of the IEEE 802.6 DQDB metropolitan area network protocol
Authors: O'Donohoe Brian 
Published: July 2007

AbstractThis paper describes a performance analysis of the IEEE 802.6 distributed queue dual bus (DQDB) metropolitan area network (MAN) protocol based on computer simulation. The MAN is a new broadband communications network that is designed to support both constant and variable bit rate applications. An overview of the important fast packet technologies and the position of the DQDB MAN is explained before the performance evaluation is carried out. The network is intended to offer high data rates and throughputs for users. The main use will be to interconnect remote LANs within a city and provide LAN‐like performance with respect to delays. The analysis given here begins with a description of the MAN and the operation of the DQDB protocol. A state description is derived and expanded upon. The use of the simulation package OPNET is described and its use in modelling DQDB is explained. The method of modelling using OPNET via an extended state description is given. A model giving the full simplified functional operation of a DQDB node is arrived at and the basic model is used to analyse a fifty‐node network under varying traffic conditions; underload, overload, varied traffic mix, etc. The unfairness characteristic of the protocol is demonstrated and the conclusions drawn are that the DQDB MAN provides a fast data transport network up to very high loadings.
A high‐speed‐retry banyan switch architecture for giga‐bit‐rate BISDN networks
Authors: Genda Kouichi , Yamanaka Naoaki , Arai Yoshimitsu , Kataoka Hideki 
Published: July 2007

AbstractThis paper proposes a high‐speed ATM switch architecture for handling cell rates of several Gb/s in a broadband communication switching system or cross‐connect system. The proposed switch architecture, named the high‐speed‐retry banyan switch, employs a bufferless banyan network between input and output buffers; a cell is repeatedly transmitted from an input buffer until it can be successfully transmitted to the desired output buffer. A simple cell‐retransmission algorithm, is employed as is a ring‐arbitration algorithm for cell conflict. They are suitable for FIFO type buffers and bufferless highspeed devices. Good traffic characteristics which are independent of switch size are achieved for an internal speed ratio of only four times the input line speed. A prototype system with the internal speed of 1·2 Gb/s is constructed in order to confirm the basic operation of the high‐speed‐retry banyan switch. The prototype system, even in its present state, could be used to realize a giga‐bit‐rate BISDN switching system.
Data link layer design issues in a home automation system
Authors: Douligeris Christos , Khawand Jean , Khawand C. 
Published: July 2007

AbstractIn this paper, we examine design issues relevant to the implementation of a data link layer of a home automation system based on the Electronics Industries Association (EIA) Consumer Electronics Bus (CEBus). The hardware and software components of the system are described along with several techniques that enhance the performance of the system, allow for a faster implementation using off‐the‐shelf components and provide low overhead. The proposed design has been incorporated into a basic home automation system (BHAS) that is used as a testbed for alternative technologies and algorithms.
A new token ring protocol and its performance for single and dual ring lan systems
Authors: Obaidat M. S. 
Published: July 2007

AbstractThis paper presents a new protocol for token ring local computer networks and its performance for single and dual ring networks using simulation modelling. The proposed protocol is a modification of the IEEE 802·5 token ring standard. In this protocol, a station can start transmission if it receives a free token or a data packet passing its interface logic. Idle stations are skipped whenever there is at least one station that has a ready packet to transmit. This is achieved by using two of the reserved bits in the frame status (FS) field. The bits used are called transmission reservation bits (TR‐bits). The TR‐bits are reset by the sending station and set by the first station that has data to transmit during the round trip of the associated packet along the ring. It is found that the proposed modified token ring (MTR) protocol provides better throughput and delay performance for both the single and dual ring networks. The reduction in mean delay of the MTR as compared to the standard token ring (STR) reaches about 45 per cent under heavy traffic conditions. Moreover, it is found that the performance of the MTR decreases as the packet size increases but remains higher than the corresponding performance of the STR for both the single and dual ring networks. The MTR provides a maximum throughput improvement of about 6 per cent over the STR for both dual and single ring cases. Finally, the proposed protocol (MTR) is easy to implement, with no extra hardware and has low cost/performance characteristics.