bluuebunny/crossref_metadata_2025_split huggingface dataset:
Anti-inflammatory and in vitro antioxidant activities of Satureja montana dry extract
Authors: Vilmosh Natalia , Georgieva-Kotetarova Maria , Kandilarov Ilin , Zlatanova-Tenisheva Hristina , Murdjeva Mariana , Kirina Veselina , Dimitrova Stela , Katsarova Mariana , Denev Petko , Kostadinova Ivanka 
Published: February 2024

Introduction: Many chronic somatic and psychiatric diseases are associated with oxidative stress and inflammation, both of which have detrimental effects on human health.
Aim: To investigate the in vitro antioxidant and in vivo immunomodulatory activities of Satureja montana dry extract.
Material and methods: The in vitro antioxidant activity of Satureja montana dry extract was assessed using ORAC, HORAC, and electrochemical methods. Immunomodulatory activity was evaluated in acute and chronic stress models by measuring the serum levels of cytokines TNF-α, IL-6, and IL-1β in a cohort of 112 male 8-week-old Wistar rats. The rats were randomly divided into 7 groups for each of both stress models and then subjected to ELISA analysis (14 groups with 8 rats in each group). The rodents were gavaged with a dry extract of Satureja montana (250 mg/kg and 500 mg/kg), rosmarinic acid (15 mg/kg), and carvacrol (500 mg/kg) for 14 days and 60 days, respectively.
Results: We demonstrated that, for all employed in vitro methods, the dried extract of Satureja montana exhibited considerable antioxidant activity. Satureja montana did not significantly lower serum concentrations of TNF-α, IL-6, or IL-1β in either stress model as compared to the positive saline control group. On the other hand, in the acute stress model, a dose of 250 mg/kg of Satureja montana significantly decreased IL-6 in comparison to carvacrol and significantly reduced TNF-α and IL-6 in comparison to rosmarinic acid.
Conclusion: Although Satureja montana dry extract has significant antioxidant activity in vitro, its influence on systemic inflammation is still unknown. Future research will look into how it affects serum levels of pro-inflammatory cytokines.
Probable autoimmune lymphoproliferative syndrome with monogenic lupus due to KRAS mutation - A rare encounter
Authors: Nayak Amiya , Gudapati Pratyusha , Tripathi Swapnil , Dass Jasmita , Aggarwal Mukul , Kumar Pradeep 
Published: February 2024

Autoimmune lymphoproliferative syndrome (ALPS) is a disease characterized by dysfunction of the T lymphocyte apoptotic pathways, mostly due to dysfunctional FAS mediated signaling. However few cases can also occur independent of FAS pathway alteration. ALPS is characterized by various immuno-hematological manifestations. Monogenic lupus is an evolving entity, which describes the etiologic role of single gene modulation in systemic lupus erythematosus. In this manuscript, we describe a case of probable ALPS with monogenic lupus caused by a novel mutation in the KRAS gene.
Diagnostic des Coopératives Agricoles de la plaine aménagée de Niofila-Douna dans la zone sud soudanienne du Burkina Faso
Authors: Zonou Bienvenu , Bazongo Pascal , Coulibaly Maliki , Kafando Boureima 
Published: February 2024

Le programme de restructuration et de mise en valeur de la plaine aménagée de Niofila/Douna au Burkina Faso, initié à cet effet, a démarré en 2012. A ce jour, sept (07) coopératives de base existantes et leur faitière ainsi que le comité d’irrigants présentent toutes des insuffisances organisationnelles. L’objectif de cette étude a consisté à faire le diagnostic des organisations paysannes de la plaine aménagée de Niofila-Douna ainsi que les contraintes liées à leur fonctionnement, puis, à en faire l’analyse et proposer des actions à entreprendre. Pour ce faire, l’outil ̏ Toile d’araignée ̋ (Td’A) qui est spécifiquement destiné à l’analyse des performances des organisations paysannes a été utilisé. Les résultats auxquels nous sommes parvenus, montrent des organisations de très faibles niveaux de performance. Les scores moyens des Organisations Paysannes (OP) varient entre 0 et 6,13 points sur 20 soit une moyenne d’ensemble de 3,13 points sur 20. C’est pourquoi, les actions urgentes d’éducation coopérative, d’accroissement des facteurs de production et le développement du partenariat s’avèrent être les mesures nécessaires pour rehausser le niveau de performance, la capacité organisationnelle et de gestion des OP de la plaine de Niofila/Douna.

English title: Agricultural cooperative diagnosis at farmlands of Niofila-Douna in the South-sudanian zone of Burkina Faso
The programme to restructure and develop the Niofila/Douna irrigated plain in Burkina Faso was launched in 2012. To date, seven (07) existing grassroots cooperatives, their umbrella organisation and the irrigators' committee all have organisational shortcomings. The aim of this study was to diagnose the farmers' organisations on the Niofila-Douna plain and the constraints on their operation, then to analyse them and propose actions to be taken. To do this, we used the ̏Canvas spider ̋(Td'A) tool, which is specifically designed to analyse the performance of farmers' organisations. The results we arrived at show organisations with very low levels of performance. The average scores for farmers' organisations (FOs) ranged from 0 to 6.13 points out of 20, giving an overall average of 3.13 points out of 20. This is why urgent action to educate cooperatives, increase production factors and develop partnerships is needed to raise the level of performance and the organisational and management capacity of FOs on the Niofila/Douna plain.
Gestion de l’agrobiodiversité par les femmes du département de Soubré (Côte d’Ivoire) : activités réalisées, espèces d’intérêts et mode d’usage
Authors: Aboli Meabla Marie Noelle Odile , Kouassi Kouame Attokora , Vroh Bi Tra Aime 
Published: February 2024

Le rôle des femmes dans les systèmes ruraux d’exploitation agricole est souvent négligé. La présente étude a permis de déterminer la contribution de ces femmes en milieu rural dans les systèmes d’exploitation de cacao, de palmier à huile et d’hévéa. Les activités menées dans les exploitations agricoles, les espèces végétales cultivées et/ou plantées, commercialisées, ont fait l’objet d’enquêtes auprès de 100 femmes. Il en ressort que 94% participent aux activités de cacao ; 6% pour l’hévéa et 3% pour le palmier à huile. La majorité des femmes participent en la réalisation de pépinière (26,56%), au planting (29,68%), au ramassage (68,75%), à l’écabossage (12,5%) dans les plantations cacaoyères et à la culture de vivriers (71,87%). Divers produits issus d’espèces natives (20%) ou exotiques (80%) sont commercialisés par ces femmes : Manihot esculenta (7%), Persea americana (6%), Capsicum annum (8%), Elaeis guineensis (9%), Musa Paradisiaca (8%), Ricinodendron heudelotii (3%), dont les bénéfices obtenus leur permettent de faire face à des besoins quotidiens de toutes sortes dans les ménages. Le maintien de ces espèces sollicitées par les femmes dans les exploitations, peut-être le gage de la protection de la biodiversité.

English title: Agrobiodiversity management by women in the department of Soubré (Côte d’Ivoire): activities carried out, species of interest and use patterns
The role of women in rural farming systems is often overloocked. The present study has determined the contribution of these rural women to cocoa, oil palm and rubber farming systems. The activities carried out on the farms, the plant species cultivated and/or planted, marked as well as the earnings obtained from sales were surveyed among 100 women. The results showed that 94% were involved in cocoa production, 6% in rubber and 3% in oil palm. The majority of women are involved in nursery (26.56%), planting (29.68%), picking (68.75%), shelling (12.5%) in cocoa plantations and growing food crops (71.87%). Various products from native (20%) or exotic (80%) species are popular for these women: Manihot esculenta (7%), Persea americana (6%), Capsicum annum (8%), Elaeis guineensis (9%), Musa paradisiaca (8%), Ricinodendron heudelotii (3%), whose profits enable them to meet all kinds of daily household needs. The maintenance of these desired species on the farms, could promote biodiversity conservation.
Evaluation de la qualité des eaux d’une ferme rizipiscicole à Bonoufla, Centreouest de la Côte d’Ivoire
Authors: Kouadio Atto Delphin , Zie Barthelemy , Konan Kouakou Seraphin , Djedje Gokou Jean Marie , Groga Noel 
Published: February 2024

Le maintien de la qualité optimale de l’eau pour la production de poissons dans les étangs rizipiscicoles constituent un défi majeur pour les pisciculteurs ivoiriens. L’étude visait à caractériser les paramètres physicochimiques et la biomasse algale des eaux des étangs rizipiscicoles d’une ferme utilisant des sous-produits agricoles. Pour ce faire, les paramètres physico-chimiques et la biomasse algale ont été collectés mensuellement dans un barrage et dans quatre étangs rizipiscicoles de grossissement de Oreochromis niloticus. Les résultats ont montré que les eaux des étangs rizipiscicoles étaient faiblement oxygénées et moins transparentes avec une forte conductivité et de matières dissoutes. Ces eaux étaient fortement ou très polluées, mais avaient une bonne aptitude à l’aquaculture. Les moyennes du pH (5,05 à 6,4), de la conductivité (133,98 à 225,58 µS/cm) et de l’oxygène dissous (3,26 à 4,03 mg/l) de l’eau des étangs rizipiscicoles étaient comprises dans les fourchettes favorables pour une meilleure croissance du tilapia. Les teneurs en nitrate et en ammonium étaient significativement plus élevées dans les étangs rizipiscicoles que dans le barrage. La biomasse algale (8408,5 à 56313,5 µg/cl) et la demande biochimique en oxygène (10 à 24,15 mg/l) étaient significativement plus élevées dans l’Etang-4. Ces résultats démontrent l’enrichissement des eaux des étangs rizipiscicoles en sels nutritifs et en microalgues par l’usage sous-produits agricoles, ce qui optimiserait la productivité du poisson et du riz.

English title: Waters quality assessment of a rice-fish farm in Bonoufla, Central- Western Côte d'Ivoire
A major challenge for fish farmers in Côte d'Ivoire is to maintain optimal water quality for fish production in rice-fish ponds. The study aimed to characterize the physico-chemical parameters and algal biomass of the water in rice-fish ponds on a farm using agricultural by- products. To accomplish this, physico-chemical parameters and algal biomass were collected monthly in a dam and in four rice-fish culture ponds where Oreochromis niloticus grown. The results showed that the water in the rice-fish ponds was poorly oxygenated and less transparent, with high conductivity and dissolved solids. These waters were heavily or very heavily polluted, but had good suitability for aquaculture. The rice-fish pond water averages for pH (5.05 to 6.4), conductivity (133.98 to 225.58 µS/cm) and dissolved oxygen (3.26 to 4.03 mg/l) were within the favorable ranges for tilapia growth. Nitrate and ammonium levels were significantly higher in the rice-fish ponds than in the dam. Algal biomass (8408.5 to 56313.5 µg/cl) and biochemical oxygen demand (10 to 24.15 mg/l) were significantly higher in Etang-4. These results demonstrate the enrichment of rice-fish pond water with nutrients and microalgae through the use of agricultural by-products, thereby optimizing fish and rice productivity.
Oral hygiene practices and status of stroke patients attending an outpatient clinic in a Nigerian tertiary hospital.
Authors: ADEYEMI Moshood Folorunsho , BELLO Abiodun , ERNEST Moninuola Adebusola , IGBEN Ehigie , WAHAB Kolawole 
Published: February 2024

Background: There may be an impairment of oral self-care post-stroke which may compromise oral hygiene and health. However, there is paucity of information on oral hygiene and oral health status of stroke patients in Nigeria.
Objective: To assess the oral hygiene and health status of stroke outpatients.
Method: A cross-sectional study of stroke patients attending the neurology outpatient clinic of a tertiary hospital in North Central Nigeria was conducted. Data on sociodemographic variables and oral health behaviour was obtained. Each patient was examined to determine the oral hygiene status using the Simplified Oral Hygiene index, DMFT index for the status of caries, Modified gingival index for the presence or absence of gingival disease and Modified Rankin score for functional impairment
Results: There were 120 participants with a mean age of 60.30±13.21 years. Poor oral hygiene status was found in 29.7% while 28.8% had good oral hygiene status. The mean DMFT was 1.37±2.672. Dental caries was seen in 48/120 (40%) while 28 (23.3%) had gingival diseases. A modified Rankin score of 3-5 was independently associated with poor oral hygiene status (OR 1.367; 95% CI 1.020-1.832; p=0.036).
Conclusion: Poor oral hygiene status is common in patients with stroke and the risk of this is higher in those with poor functional status. Oral health status should be considered in the holistic rehabilitation of stroke patients.
Aproximación teórica de la construcción del proyecto de investigación en estudiantes de educación media general
Authors: Herrera Derianyi 
Published: February 2024

El presente ensayo, es un análisis de la realidad que viven los estudiantes de educación media general en el Liceo Bolivariano Raquel Monasterio de Barquisimeto, Edo. Lara, tiene como finalidad generar reflexiones teóricas con respecto a la construcción de los proyectos de investigación a partir de las experiencias y vivencias de los estudiantes de dicha casa de estudio. El estudio se apoyó en el enfoque cualitativo, desde el paradigma interpretativo y sustentado con el método fenomenológico. Se concluye la deficiencia en el área investigativa, lo que permite reflexionar sobre lo crítico de la situación y nos recuerda la importancia de la investigación en la educación, como base para la formación estudiantil. Este trabajo investigativo será de relevancia para la institución, ya que tendrá una perspectiva diferente en cuanto a la elaboración de trabajos investigativos, y lograr desarrollar en los estudiantes un potencial como investigadores desde el nivel de educación media.
MEMANFAATKAN METODE SMART SEBAGAI REKOMENDASI WATER PARK TERBAIK BAGI WISATAWAN DI WILAYAH PEMATANGSIANTAR
Authors: Parlina Iin Iin , Irawan Eka 
Published: February 2024

Water Park Pematangsiantar merupakan tempat rekreasi bermain air yang menjadi salah satu perhatian dan daya tarik wisatawan lokal maupun luar kota. Tempat rekreasi ini berada di beberapa kecamatan di kota Pematangsiantar. Kelebihan dari masing-masing lokasi Water Park memiliki ciri khas tersendiri seperti kondisi yang dilihat dari fasilitas, keamanan, jarak, kebersihan dan biaya harga tiket. Berdasarkan perbedaan inilah yang dijadikan dasar untuk membuat alternatif pencarian informasi tentang kawasan Water Park. Dengan tujuan agar penelitian ini dapat memberikan solusi keputusan yang terbaik sebagai rekomendasi bagi wisatawan lokal maupun luar kota, sehingga para wisatawan tersebut dapat mengetahui informasi Water Park mana saja yang paling banyak pengunjungnya. Pada penelitian ini digunakan 5 water park sebagai bahan alternatif yaitu Water Park Bahsorma, Water Park Siantar, Water Park Martoba, Water Park Marihat, dan Water Park Indah Karangsari. Proses perhitungan perangkingan dilakukan dengan menggunakan model sistem pendukung keputusan dengan menerapkan metode SMART (Simple Multi Attribute Rating Technique), dimana hasil perhitungan pengambilan keputusan terbaik adalah Siantar Matoba Water Park dengan nilai 0,70 sebagai alternatif terbaik di peringkat pertama, sedangkan Water Park Bahsorma dengan nilai 0,68 menjadi alternatif yang berada di peringkat kedua dan selanjutnya menjadi rekomendasi Water Park terbaik bagi wisatawan lokal maupun luar kota di wilayah Pematangsiantar.

Kata Kunci : Sistem Pendukung Keputusan, SMART, Water Park, Kawasan Pematangsiantar
PEMBUATAN BIOETANOL DARI BATANG KELAPA SAWIT (Elais Guineensis Jacq.) MELALUI PROSES PRETREATMENT MENGGUNAKAN H2SO4 DAN FERMENTASI MENGGUNAKAN RAGI ROTI (Saccharomyces cerevisiae)
Authors: Giyanto  , Saragih Sri Wahyuna , Rahimah  
Published: February 2024

Unproductive oil palm stems can produce Umbut which is the raw material for bioethanol production. In general, the production process of bioethanol from lignocellulosic materials includes oil palm stalks. The bioethanol production process goes through several stages of physical, chemical or biological pretreatment, polymer saccharification, sugar fermentation, and ethanol separation and purification. This study aims to determine the production of bioethanol from oil palm stems (Elaeis Guineensis Jacq) through a pretreatment process using H2S04 and fermentation using baker's yeast (Saccharomyces cerevisiae). The method used in this study was a Completely Randomized Design (CRD) Non Factorial with 3 treatment levels and 1 control, and 3 repetitions (Triplo) with a total sample of 12 samples. The resulting bioethanol is then tested (moisture content, yield, and pH). The resulting data were analyzed using ANOVA and Duncan's test. Based on the results of this study, the best treatment was found in the H0 treatment with a yield of 34.5%, 1.52% moisture content and 5,6 % pH
Investigating the Biological Composition and Injurious Tendencies of the Rotator Cuff Muscles
Authors: Karnati Phanindra , Crawford Mary 
Published: February 2024

The construction of our human anatomy is one of great importance. In the grand scheme of the rotational torque that our skeletomuscular body exerts, one such key structure is the Rotator Cuff Muscles. To function as a biologically sound component of the human body, the muscular composition of the Four Major Muscles: the Supraspinatus, Subscapularis, Teres Minor, and the Infraspinatus. I explored the muscular composition and substance matter of each of these 4 crucial muscles of the Rotator Cuff. Through the various connections between the movement, location (relative to the midline of the body), and the composition of tissue, an apparent connection between the muscular damage in each of these listed muscles can be observed as well.
Research or Espionage: The Thousand Talents Plan and its Impact on Sino-US Geopolitics
Authors: Suarez Mario 
Published: February 2024

Introduction: The Thousand Talent Plan (TTP) is a Chinese initiative to attract experts in science and technology. The program has been surrounded by controversy since its creation. Methods: this paper explores the success and flaws of the implementation of the plan and reviews particular cases to expose the challenges that surround such initiative. Results: Some American scientists have been victims of contracting deception and others accused of suspected espionage while participating on the TTP. Discussion: the United States government has implemented a variety of methods designed to prevent the transfer of protected information from happening, with varying degrees of effectiveness.
Faktor yang Mempengaruhi Kesadaran Melakukan Pemeriksaan Kehamilan di Puskesmas Pijorkoling Kota Padangsidimpuan
Authors: Harahap Yanna Wari , Suryati Suryati , Ahmad Haslinah , Nurlaila Nurlaila , Gusdita Rahmi 
Published: February 2024

Pemeriksaan antenatalcare (ANC) adalah pemeriksaan kehamilan untuk mengoptimalkan kesehatan mental dan fisik ibu hamil. Cakupan K4 Padangsidimpuan tahun 2018 sebesar67%. Penelitian ini bertujuan untuk menganalisis hubungan pengetahuan, umur dan paritas dengan kesadaran melakukan K4 di Puskesmas Pijorkoling kota Padangsidimpuan tahun 2019. Desain penelitian adalah crosssectional. Populasi dalam penelitian ini adalah seluruh ibu hamil Trimester III dengan usia kehamilan 36 minggu atau lebih sebanyak 40 orang. Teknik pengambilan sampel yaitu total population sehingga jumlah sampel adalah 40 orang. Data diperoleh dari Puskesmas Pijorkoling Padangsidimpuan dan melalui hasil wawancara dengan menggunakan kuesioner. Metode analisa data dianalisis secara univariat, bivariat dengan menggunakan uji Chisquare dengan nilai ? sebesar 95%. Hasil penelitian didapatkan bahwa da hubungan antara pengetahuan (0,038), umur (0,037), status paritas (0,028) dengan kesadaran melakukan pemeriksaan kehamilan di Puskesmas Pijorkoling Tahun 2019. Diharapkan kepada Puskesmas Pijorkoling melakukan inovasi baru seperti kelompok belajar ibu hamil, senam ibu hamil agar ibu hamil ramai berkunjung dan menginformasikan ke lintas sektor agar dapat memberikan perubahan perilaku masyarakat khususnya ibu hamil.
Study and Characterization of Copper and Titanium Oxides Nanostructures for Some Molecular and Biological Applications
Authors: Abdulazeez Alhamd Omar , Ghazi Ali Ghazwan , Salih Hasan Aljuboori Mutaz 
Published: February 2024

In this work, Copper and Titanium nanocomposites (NPs) were prepared by mixture exchange process with ratios (25, 50 and 75 % CuO-TiO2). The biological activity was studied, and it was found that the concentrations of 50 and 100 µg/mL of 50 and 75 % CuO-TiO2 were the best concentrations, Low concentrations of the nanoparticle mixture at 25 µg/mL also stimulated the growth of symbiotic bacteria. The mixture of nanoparticles was easier to prepare and more effective in inhibiting bacterial growth. biochemical test and PCR were performed to confirm the identity of the studied bacteria. While isolating the bacteria, a new type of bacteria was detected and registered in the Global Gen Bank under accession No. OP942239. Surface and structure properties have been studied using FESEM, EDS analysis, XRD and FTIR respectively. It can be seen that the size and diameter of the nanocomposite increase with the weight ratio of CuO-TiO2. The aggregated CuO-TiO2 nanostructures with different ratios were transformed gradually into a uniform spherical shape. The average size of the CuO/TiO2 composite was found to be about 32.122, 29.865 and 27.607 nm at 25, 50 and 75 % CuO-TiO2 respectively. While the mean sizes of CuO and TiO2 were 25.35 and 34.38 nm respectively. The crystalline size decreases after the ion exchange process, which could be due to the diffraction peaks being broad in all the samples of Copper Titanate at the surface. Subsequently, adding Copper particles to the TiO2 film can improve the performance of the material.
HIGHLIGHTSThe nanostructure CuO-TiO2 was created through various loading ratios. These NPs’ efficiency was calculated using a number of techniques, including FTIR, X-ray diffraction, EDS spectra, and FESEM. The observations indicate that molecular transition parameters play an essential role in determining the size, shape, and functionality of CuO- TiO2 NPs. The sharp peaks observed in the composites indicated higher crystallinity in CuO. In addition, two types of NPs have shown promising effects in inhibiting NPs aggregation and enhancing biological effects but the potential of these NPs against different bacteria may differ. Thus, further research and testing is needed to assess its efficacy and human health and environmental impact before considering its use. In conclusion, copper and titanium NPs have their distinct advantages in bacterial inhibition, and the choice between them should be based on specific conditions and environmentally friendly factors.
GRAPHICAL ABSTRACT