bluuebunny/crossref_metadata_2025_split huggingface dataset:
The scientific discovery and subsequent history of the douc monkey Pygathrix nemaeus (Linnaeus, 1771) near Da Nang, Vietnam
Authors: Brandon-Jones Douglas 
Published: April 2024

Abstract
In 1750 Pierre Poivre donated the holotype of the douc monkey Pygathrix nemaeus to R.-A. F. de Réaumur. Its type locality is here restricted from “Cochinchine” to near Da Nang, Vietnam. In 1757, Buffon appropriated the holotype for the King’s collection, wrongly inferring that the species lacks ischial callosities, and conflating it with the sifaka of Madagascar. “D’ouc” is evidently a corruption of Voọc, the Vietnamese word for colobine monkey. In 1819, a French crew shot 100 doucs before breakfast on a mountain near Da Nang. In 2016, the whole mountain population was estimated at 70. By 1831 doucs had learnt to fear gunfire, but locals accepted their proximity, and provided some protection from meat-seeking foreigners. Several doucs were collected for museums in the 19th and 20th century; in 1897 two even lived for a fortnight at the Jardin des Plantes, Paris. The douc was observed and collected near Da Nang during its miraculous survival of the Vietnam War; its evergreen forest habitat surprisingly resilient. This situation is rapidly deteriorating, as forests are reduced to isolated pockets, and hunting prohibitions unenforced. The closely-monitored Mount Son Tra douc population was expanding, but tourist development is illegally eroding the Nature Reserve.
Observations of a greater sac-winged bat pup (Saccopteryx bilineata) with a chromatic disorder
Authors: Fernandez Ahana A. , Tietge Marisa , Ripperger Simon 
Published: April 2024

Abstract
Chromatic disorders in bats are typically documented by brief, incidental observations of individuals at day roosts or by accidental captures during mist-netting. Such descriptions usually lack observations on social behaviour including interactions between bats with aberrant pigmentation and other individuals. Here, we report the first observation of leucism in the greater sac-winged bat Saccopteryx bilineata. Over the course of six weeks, we were able to follow the development of a wild pup with a conspicuous aberrant pigmentation, by observing it in its day roost. Our observations indicate that the vocal and behavioural development of the pup was entirely normal, as well as the integration into its social group. After six weeks, when the pup was already foraging individually, it did not return to its colony in the morning, indicating that it may have been preyed on.
How morphological decomposition manifests itself in the duration of the inter-morpheme period of silence in Russian prefixed verbs
Authors: Monakhov Sergei 
Published: April 2024

Summary
This study tests the morphological gradience theory on Russian prefixed verbs. With the help of a specially designed experiment, I offer evidence that verbs with prefixes that have prepositional counterparts and verbs with prefixes that exist only as bound morphemes reveal significant differences in terms of their morphological decomposition. In the pronunciation of native speakers, there tends to be a significantly longer silent period between prepositional prefixes and bases than between unprepositional prefixes and bases due to the compositional nature of the former and the non-compositional nature of the latter. Drawing on these findings, I contend that Russian prefixed verbs can be analysed as constructional schemas and that the degree of their morphological decomposition depends upon the different levels of activation of their sequential and lexical links.
The description of mourning in Anna Stanisławska’s autobiography: The context of early modern theory of emotion
Authors: Jekutsch Ulrike 
Published: April 2024

Summary
Anna Zbąska née Stanisławska, a lady of the Polish high aristocracy, wrote the story of her life in 1685 after the loss of her father, a divorce from her first and the deaths of her second and third husband, all of which she experienced in the course of approximately 16 years. She told her life as a narrative in lamentations, in a series of 77 dirges (treny) in which she mourned her beloved ones as well as her own – childless, fruitless – life. Though it has been frequently noted in recent research that the text is dominated by the expression of mourning, this central aspect has not been made a subject of a study in its own right. This article aims to examine the description of mourning by Stanisławska and her way of handling her afflictions by discussing them in the context of conceptualizations of emotions in the seventeenth century.
Aptamer-based Theranostics in Oncology: Design Strategies and Limitations
Authors: Trivedi Jyoti , Yasir Mohammad , Maurya Rahul K. , Tripathi Alok Shiomurti 
Published: April 2024

Abstract
Cancer remains a major global health burden, necessitating innovative approaches for improved diagnosis and treatment. Aptamer-based theranostics have gained attention in the field of cancer research and treatment. Aptamers can be used as targeting ligands for the delivery of therapeutic agents to cancer cells, as well as for the detection and imaging of cancer, due to high binding affinity and selectivity. Aptamers are also being investigated as anticancer drugs. Specifically, aptamers serve as a tool for controlling protein activity via protein-protein and protein-ligand interactions. The aptamer-exosome technology improves aptamer targeting. To gather relevant data, we searched scientific databases, including PubMed/Medline, Google Scholar, Wiley, Web of Science, and Springer. Despite challenges, theranostics, environmental monitoring, biosensing, and other fields could benefit from the use of aptamer technology. This review discusses the standard methods for producing aptamers, including green aptamers, and potential applications in diagnostics. Aptamers are useful in biotherapy and as anticancer drugs, and this article gives a thorough overview of both with examples. We also covered aptamer-exosome technologies, aptasensors, and their diagnostic and therapeutic applications. We investigated recent systematic evolution of ligands by exponential enrichment (SELEX) methodologies with a focus on carrier materials and technical advances, and discuss the difficulties in creating aptamers that are more practical, highly efficient, and stable.
Two rare cases of benign struma ovarii with malignant recurrence
Authors: Kantreva Kanella , Paschou Stavroula A , Stefanaki Katerina , Pappa Kanella , Kazakou Paraskevi , Vrachnis Dionysios , Kavoura Evangelia , Pavlakis Kitty , Giovannopoulou Eirini , Lathouras Konstantinos , Alevizaki Maria , Saltiki Katerina 
Published: April 2024

Summary
Struma ovarii is an ovarian teratoma that comprises 2–5% of all ovarian teratomas. Malignant transformation of struma ovarii occurs in less than 5% of all cases, and metastatic disease is even rarer. We report two cases initially diagnosed with benign struma ovarii that presented malignant transformation, specifically highly differentiated follicular carcinoma of the ovary (HDFCO), some years after the first diagnosis. Case 1 concerns a 37-year-old female featuring HDFCO of the right ovary with multiple metastatic foci, who was diagnosed with benign struma ovarii 14 years ago. Case 2 concerns a 26-year-old female diagnosed with HDFCO of the left ovary. This patient was initially diagnosed with benign struma ovarii 6 years ago that recurred 4 years after the diagnosis. Both patients were treated with surgery, adjunctive total thyroidectomy, and radioactive iodine (131I) therapy.

Learning points

Malignant transformation of struma ovarii is very rare (<5%).

Diagnosis of HDFCO without extra ovarian dissemination is difficult due to the resemblance of its histological appearance with normal thyroid tissue.

There is no consensus on the postoperative treatment of malignant struma ovarii (MSO). Clinical and histological features of MSO should be assessed for the postoperative treatment decisions.

TSH suppression and thyroglobulin level measurements are necessary for patient follow-up.
Improving Employee Safety Through a Comprehensive Patient Behavioral Program
Authors: Laprime Amanda , Kanaley Rebecca , Keller Amy , Stephen Steve J. , Schriefer Jan , Fallon Anne , Sosa Tina 
Published: April 2024

BACKGROUND
Health care workers in the United States are facing increasing rates of exposure to aggressive behavior, resulting in an increase in employee injuries related specifically to patient behavioral events. By leveraging interprofessional collaboration and system-level innovation, we aimed to reduce the rate of employee injuries related to patient behavioral events at a children’s hospital by 50% over a 3-year period.

METHODS
An interdisciplinary quality improvement team comprising physicians, behavior analysts, nursing, and other key stakeholders developed a comprehensive behavior program in our children’s hospital. The team developed 5 key pillars: aggression mitigation tools, clinical resources, advanced training, screening and management, and behavior emergency response. The outcome measure was rate of reported employee safety events related to patient behavioral events. This was tracked via prospective time series analysis statistical process control chart using established rules to detect special cause variation.

RESULTS
The average rate of employee injuries resulting from patient behavioral events decreased from 0.96 to 0.39 per 1000 adjusted patient-days, with special cause variation observed on a statistical process control U-chart. This improvement has been sustained for 16 months. Staff members who experienced injuries included nurses and patient technicians, with common antecedents to injuries including medical interventions or patient requests that could not be safely met.

CONCLUSIONS
A unified and multimodal system aimed to address pediatric patient behavioral events can reduce employee injuries and foster a culture of employee safety in the pediatric inpatient setting.
Occupational therapy practice with burn injuries: A Rapid Review
Authors: Van Biljon Hester M , Engelbrecht Madri , Van der Walt Janke , Soeker Shaheed 
Published: April 2024

Introduction: The Occupational Therapy Association of South African commissioned a task team to gather evidence that would inform upcoming National Health policies on the role and practice of occupational therapists. This rapid review aimed to identify level 1 and 2 peer reviewed published evidence that describes occupational therapists’ practice and intervention in all types of burn injuries, at all levels of care, and for all age groups.
Method: Using the South African Department of Health template and the Cochran Rapid Reviews method guide, a search for level 1 and 2 evidence sourced articles from CINAHL (EBSCO), MEDLINE (EBSCO), the Cochrane Library (Wiley) and OTSeeker data bases through the Stellenbosch University library with hand searching of references in the selected articles. Rayyan was used for the screening and selection of articles. The CASP appraisal tool was used for risk bias and quality assessment of the selected articles. Data was captured in Excel and Word, and analysed and synthesised in Microsoft Excel and Taguette. Results were presented in the form of an online workshop to stakeholders and discussions and questions incorporated into the discussion and conclusion of this review.
Results: Eleven articles were selected and their quality assessed. Seven categories of evidence of occupational therapy interventions were extracted from selected articles: pain, oedema, scaring and abnormal skin sensations, joints and range of motion, psycho-social and functional impact of burn injuries, the education of burn injury victims and their families, and vocational rehabilitation. All interventions took place in healthcare facilities. Nine articles referred to occupational therapists working in multi-disciplinary teams. Occupational therapist worked with children and adult burn injury victims and with a variety of type of burn injury from acute to post discharge phases.
Conclusion: There is level 1 and 2 evidence conderming occupational therapy intervention with burn injury victims with all ages and at all stages of injury within healthcare facilities. None of the evidence found is from the South African context. Such levels of evidence are needed to promote occupational therapy intervention in primary, preventative and community contexts.
Implications for practice:
Internationally there is level 1 and 2 evidence that conderms occupational therapists are members of multi-disciplinary teams addressing the functional ability and participation in activities of burn injury victims. None of this evidence is from South Africa. As a matter of priority, South African clinical occupational therapy practice and intervention within the deeld of burn injury, need to be researched and disseminated as level 1 and 2 evidence
Occupational therapy interventions for Autism Spectrum Disorders - a Rapid Review
Authors: Van der Walt Janke , Engelbrecht Madri , Van Biljon Hester M , Soeker Shaheed 
Published: April 2024

Introduction: This rapid review aimed to synthesise evidence for occupational therapy intervention in the management of autism spectrum disorders. The review forms part of a series of rapid reviews commissioned by the Occupational Therapy Association of South Africa to help inform decision making as South Africa prepares for a new health system.
Method: Level I and II research studies published from 2017 - 2022 were considered for inclusion. Electronic database searches were conducted on the Cochrane database. The identified records were screened in Rayyan according to inclusion and exclusion criteria. Quality assessment of the selected articles was done with the CASP appraisal tool. Data were extracted to a custom Microsoft Excel® worksheet and analysed quantitatively by percentage/frequency and qualitatively by thematic analysis of statements.
Results: Thirty-eight records were selected. These included 30 systematic reviews and eight randomised controlled trials. Twelve intervention domains across four age groups were identified with sensory integration and social skills interventions most frequently examined. Interventions were delivered across various venues, including mediation and technology (e.g., telehealth interventions). A number of diﬀerent outcome measures were used.
Conclusion: There is evidence to support the eﬀectiveness of occupational therapy interventions for autism spectrum disorder across the lifespan for twelve diﬀerent domains.
Implications for practice

Occupational Therapists are involved in the provision of therapy intervention across all age groups for people with ASD.
Intervention can successfully take place in a clinic setting, but also at home or through means of technology.
There is growing evidence for sensory integration therapy or techniques when considering functional outcomes when treating people with ASD.
There is a lack of Level I and II research in the form of randomised control trials and systematic reviews regarding ASD intervention in sub-Saharan Africa.
The role of occupational therapy serving LGBTQIA+ people: Retrospective perceptions of an occupational therapist
Authors: Ncwane Thabani , Tintinger Sanet , Ebrahim Nasneen 
Published: April 2024

Introduction and aim: LGBTQIA+ people constitute a minority group that navigate their occupational engagement within a historically entrenched system of oppression. This opinion piece addresses a subject matter that is increasingly garnering attention from the international health science community, yet it remains insuﬃciently explored in South African occupational therapy dialogues. The aim of this paper is to stimulate critical reflection among occupational therapists on the discourses that underpin our daily practice. By utilising the person- environment-occupation model, we seek to demonstrate the unique and essential role of occupational therapy in serving LGBTQIA+ people within the South African context.
Conclusion: Although occupational therapists are trained to consider all aspects of a person, discussions around gender are rarely emphasised in undergraduate training or clinical practice. This opinion piece demonstrates the roles that occupational therapists may play when working with LGBTQIA+ people to provide services that are holistic and relevant to their needs and contexts. Recognizing the impact of everyday occupational therapy practices on LGBTQIA+ individuals is crucial, requiring a commitment to inclusivity and continuous reflection within the field of occupational therapy.
Implications for practice
Occupational therapists can play an important role in serving LGBTQIA+ individuals when they are committed to recognizing how dominant discourses about this group can be sustained through the everyday practices of delivering occupational therapy.
Surgical treatment of a massive soft tissue neurofibroma in neurofibromatosis type 1
Authors: Valiev A. K. , Salkov A. G. , Petrochenko N. S. 
Published: April 2024

Introduction. Neurofibromas developing in neurofibromatosis type 1 rarely grow to a large size. However, in cases of massive lesions, selection of optimal treatment tactics can be complicated. Clinicians usually resort to surgical treatment which currently serves as an effective instrument for improving patients’ quality of life and for achieving good cosmetic results.Aim. To describe a successful experience of surgical treatment in a patient with giant neurofibroma type 1 affecting a massive pool of soft tissues.Clinical case. Patient, 22 years, sought medical help at the N.N. Blokhin National Medical Research Center of Oncology with diagnosis of neurofibromatosis type 1 with massive lesions in the tissues of the lower third of the back, gluteal region, thighs. The disease has existed since birth, family medical history is fraught: father died of malignant manifestation of a neurogenic tumor. The younger sister is also diagnosed with neurofibromatosis affecting the brain and manifesting through cafe au lait spots on the body. Due to massive tumors significantly decreasing the patient’s quality of life, cytoreductive surgical treatment was prescribed aimed at maximally radical resection of all available tumors to alleviate the patient’s condition.Conclusion. The presented clinical case demonstrates successful experience of surgical treatment of a patient with giant neurofibroma affecting a massive pool of soft tissues.
Differentiation of the Competence of the Prosecutor's Office and the Court to Ensure the Legality of Operational Investigative Activities
Authors: Nikitin E. L. , Zorin V. S. 
Published: April 2024

The relevance of the study is determined by the role and place of the legal institution for the protection of human, civil rights, and freedoms as an attribute of the rule of law, the need for proper control and supervisionof their compliance. The Constitution of the Russian Federation proclaims that a person, his rights and freedoms are the highest value, and the state is obliged to recognize, respect and protect the rights and freedoms of man and citizen, judicial protection is guaranteed to everyone. This implies, on the one hand, that everyone is guaranteed to ensure the implementation of the active right to appeal in court decisions, actions or inactions of public authorities and their officials, and on the other hand, verification of compliance with the passive right, which is mainly implemented through control and supervisory procedures. At the same time, in the process of implementing certain functions of the state (in particular, law enforcement), authorized bodies are allowed to apply measures that significantly limit the fundamental constitutional rights and freedoms of a person. An important place among these types of state activities is occupied by operational investigative activities (OIA). In the field of OIA, citizens are often limited in their ability to independently defend their rights and legitimate interests, and therefore a special role in this area is given to the court and the prosecutor’s office. As part of the study, an attempt was made to comprehensively study the theoretical, legal and practical issues of organizing the activities of the prosecutor and the court to protect human and civil rights, the legitimate interests of legal entities in the production of operational investigations, analyze the relationship between prosecutorial and judicial activities, and develop an organic mechanism for their implementation, excluding «mutual substitution» and duplication of competencies.
Primary Cutaneous Adenoid Cystic Carcinoma in a Rare Location With an Immune Response to a BNT162b2 Vaccine
Authors: Yilmaz Abdurrahman , Goker Barlas , Gedikoglu Mustafa Gokhan , Ayvaz Mehmet , Tokgozoglu Ahmet Mazhar 
Published: April 2024

Case:
In this report, a rare case of primary cutaneous adenoid cystic carcinoma (PCACC) localized in the subcutaneous tissue of the scapular region that grew after BNT162b2 corona virus disease of 2019 (COVID-19) vaccination is presented and may be explained by CD4 and CD8 cell infiltration. The BNT162b2 mRNA vaccine has been associated with a multisystem inflammatory syndrome (MIS-V). A comparable immune reaction could potentially enhance tumor growth rate.

Conclusion:
Primary cutaneous adenoid cystic carcinomas are rare tumors with unique locations. Further studies with case series are required to establish management algorithms for PCACC and investigate the potential effect of vaccination.
Pauperization of Emerin from nuclear envelope during chromatin bridge resolution drives prostate cancer cell migration and invasiveness
Authors: Nastaly Paulina , Popęda Marta , Kowalski Kamil , Wenta Tomasz , Beznoussenko Galina , Rychlowski Michal , Mironov Alexandre , Lavagnino Zeno , Barozzi Sara , Richert Julia , Bertolio Rebecca , Szade Jolanta , Miszewski Kevin , Matuszewski Marcin , Żaczek Anna , Braga Luca , Sal Giannino Del , Bednarz-Knoll Natalia , Maiuri Paolo 
Published: April 2024

Abstract

Micronuclei (MN) can arise from many causes, including the breakage of aberrant cytokinetic chromatin bridge. The frequent observation of MN in tumors raises the specter that they might not merely be passive elements but could instead play active roles in tumor progression. Here, we propose a mechanism that the presence of micronuclei could induce specific phenotypic and functional changes to the cell and lead to increased cancer invasive potential. Through the integration of diverse imaging and molecular techniques in vitro, supported by clinical samples from D’Amico high-risk prostate cancer (PCa) patients, our study demonstrates that the resolution of chromosome bridges can result in the accumulation of EMD and the formation of EMD-rich MN. Such structure is negative for Lamin A/C, positive for Lamin-B receptor and Sec61β. It can act as a protein sink and result in EMD pauperization from the nuclear envelope. The phenotype of emerin mis-localization is associated with molecular signature that correlates to worse prognosis in PCa and is enriched in metastatic samples. Emerin mis-localization corresponds with migratory and invasive properties of tumor cells, especially in the context collagen-rich microenvironment. Our study demonstrates that the mis-localization of emerin to MN induces increased cell invasiveness, thereby exacerbating patient’s prognosis.