bluuebunny/crossref_metadata_2025_split huggingface dataset:
Perancangan Strategi Kreatif Konten Visual Sosial Media Situ Cileunca Pangalengan Kab. Bandung
Authors: Muthmainnah Ligar , Yusup Nuke Rahmadina 
Published: March 2024

Kota Bandung memiliki keindahan alam yang masih asri khususnya di daerah Kab. Bandung. Masih banyak lahan hijau yang sekarang sudah mulai dikelola dengan baik, ditata dengan rapih, dan dibuat lebih nyaman untuk pengunjung. Salah satunya adalah Situ Cilenca yang terdapat di Pangalengan Kab. Bandung, merupakan destinasi wisata yang memiliki pemandangan perbukitan yang hijau dan hutan yang lebat serta hamparan danau yang luas. Selain memiliki keindahan alam yang menajubkan, Situ Cileunca menawarkan beberapa fasilatas atraksi permainan yang ditawarkan berupa outbond training seperti arung jeram (rafting), flying fox, ATV dan juga menyediakan camping ground. Dengan harga tiket masuk yang terjangkau, Situ Cileunca sudah memiliki fasilitas yang bisa dikatakan lengkap. Apalagi saat ini pihak Disbudpar Kabupaten Bandung sedang melakukan penataan fasilitas yang ada di Situ Cileunca secara bertahap. Namun sayangnya Situ Cileunca belum memanfaatkan dengan maksimal penggunaan media sosial, sehingga tak jarang banyak yang belum mengetahui Situ Cileunca secara terperinci. Perancangan ini dibuat untuk menerapkan strategi kreatif dalam media sosial untuk memaksimalkan promosi low budget high impact bagi Situ Cileunca. Dalam pengumpulan datanya, perancangan ini menggunakan mix method, dengan melakukan wawancara, observasi, dan membagikan kuisioner pada warga kota Bandung rentang usia 19-25 tahun. Hasil dari perancangan ini dapat dilihat bahawa dengan memaksimalkan media sosial akan lebih efektif dalam mengenalkan dan menyebarkan informasi tentang Situ Cileunca Pangalengan Kab. Bandung.
Perbandingan Efektivitas Ekstrak Daun Chromolaena Odorata Dan Povidone Iodine 10% Terhadap Kepadatan Kolagen Pada Luka Insisi Tikus Putih (Spraguedawley)
Authors: Binsasi Richarda Anggraini , Telussa Arley Sadra , Damanik Efrisca M 
Published: March 2024

Latar Belakang: Luka merupakan hilangnya atau rusaknya sebagian jaringan tubuh. Masih sering didapatkan kecenderungan penggunaan obat tradisional untuk penanganan luka terutama di Indonesia. Salah satu dari tanaman tradisional tersebut yaitu Chromolaena odorata. Chromolaena odorata mempunyai efek terhadap penyembuhan luka dan dapat meningkatkan ekspresi kolagen. Povidone iodine yang menjadi standar perawatan luka dan mempunyai sifat antiseptik.
Tujuan Penelitian: Mengetahui perbandingan efektivitas daun Chromolaena odorata dan Povidone iodine 10% terhadap kepadatan kolagen luka insisi tikus putih (Sprague dawley).
Metode: Penelitian ini bersifat eksperimental laboratorium dengan 4 kelompok yaitu kelompok kontrol (P1) diberi perawatan Povidone iodine 10%,kelompok pembanding (P1,P2,P3) yang diberi perawatan Chromolaena odorata 10%, 15% dan 20%. Pengamatan kepadatan kolagen secara mikroskopis menggunakan kriteria Nagaoka. Analisis data mengunakan uji Kruskall Wallis.
Hasil : Pada penelitian ini diperoleh hasil nilai p=0,609 (>0,05).
Kesimpulan: Pemberian ekstrak daun Chromolaena odorata dan Povidone iodine 10% tidak menunjukkan perbedaan efektivitas yang signifikan terhadap kepadatan kolagen luka insisi tikus putih galur Sprague dawley
IDENTIFIKASI VARIAN GENETIK TERKAIT KEJADIAN INFARK MIOKARD MELALUI PENDEKATAN BIOINFORMATIK
Authors: Capritasari Rafiastiana , Irham Muhammad , Azzahra Fara , Nugraha Davit , Yusuf Anna Lesmanasari , Astuti Febriana , Zulkifli Zulkifli , Wicaksono Anggoro , Hendryawan Andhika Nor , Nurgraheni Tiyas Putri , Kusmini Kusmini , Alifiar Ilham , Suzana Dona 
Published: March 2024

Faktor risiko terjadinya penyakit kardiovaskuler selain faktor risiko konvensional (perokok, hipertensi, dislipidemia, diabetes militus dan obesitas) terdapat juga faktor genetik serta faktor risiko non-konvensional seperti kecemasan, stres dan depresi. Tujuan dari penelitian ini yaitu mengidentifikasi variasi genetik yang terkait dengan patogenesis infark miokard pada berbagai populasi dengan menggunakan basis data genom dan pendekatan bioinformatika. Hasil terdapat tiga varian genetik yaitu gen APOE, ZC3HC1 dan ALDH2 yang memiliki potensi kerusakan terhadap protein DNA sehingga dapat menyebabkan kejadian infark miokard. SNP dengan kode rs7412, rs11556924 dan rs671 merupakan SNP yang paling kuat dikaitkan dengan kejadian infark miokard sehingga dapat direkomendasikan sebagai risiko genetik.
PREPARASI DAN KARAKTERISASI SELULOSA MIKROKRISTALIN DARI FERMENTASI GANYONG SEBAGAI EKSIPIEN DALAM SEDIAAN TABLET
Authors: Rum Ira adiyati , Maemah Maemah , Supriadi Dadih 
Published: March 2024

Keywords: Acetobacter xylinum, Avicel PH 102, Microcrystalline Cellulose, Nata de Ganyong, Tablet Excipient ABSTRAK Latar belakang : Hampir sekitar 96% bahan baku di industri farmasi masih bergantung pada bahan baku impor. Selulosa mikrokristalin (SM) merupakan salah satu bahan baku impor yang digunakan dalam pembuatan sediaan tablet. Nata de ganyong dapat dijadikan sebagai alternatif untuk memperoleh SM. Metode : Umbi ganyong dibuat nata dengan cara fermentasi oleh Acetobacter xylinum. SM diisolasi dari nata de ganyong dengan pemanasan alkali dan hidrolisis asam. SM nata de ganyong (SMNDG) diformulasikan dalam sediaan tablet dengan metode kempa langsung. Hasil: Uji organoleptik SMNDG adalah sebuk putih agak kecoklatan, tidak berbau, tidak berasa. Uji identifikasi menunjukkan warna biru violet. Uji pati menunjukkan warna putih. Karakteristik SMNDG lainnya diantaranya pH 6,56; kelarutan dalam air 0,2085%; sifat alir 11,0035g/detik; sudut diam 43,6698⁰; kompresibilitas 16,2393%; kadar air 4,3%; susut pengeringan 4,7286%.. Pengujian SEM SM nata de ganyong menunjukkan kemiripan morfologi dan ukuran dengan Avicel PH 102. Evaluasi sediaan tablet meliputi uji keseragaman ukuran, keragaman bobot, kekerasan tablet, kerapuhan, waktu hancur dan disolusi. Kesimpulan: SMNDG memiliki karakteristik yang sama dengan Avicel PH 102 sebagai eksipien dalam sediaan tablet dengan metode kempa langsung. Kata kunci : Acetobacter xylinum, Avicel PH 102, Eksipien Tablet, Nata de Ganyong, Selulosa MikrokristalinABSTRACT Background: Almost 96% of raw materials in the pharmaceutical industry still depended on the imported raw materials. Microcrystalline cellulose (MS) is one of imported raw materials that used in tablet dosage form. Nata de ganyong can be used as an alternative to produce MS. Method: Nata was made of the fermentation of ganyong by Acetobacter xylinum. MS was isolated from nata de ganyong by alkali heating and acid hydrolysis. MS nata de ganyong (MSNDG) was formulated in tablet preparations by direct compression method. Results: The organoleptic of MSNDG was a powder, white slightly brown, odorless, tasteless. The identification test showed blue-violet. The starch test showed white. The other characteristics of MSNDG had included pH 6,56; water-soluble substances 0.2085%; flowability 11,0035 g/sec; angle of repose 43,6698⁰; compressibility 16.2393%; moisture content 4.3%; loss on drying 4,7286%. The SEM test of MSNDG showed a morphological and size similarity with Avicel PH 102. Evaluation of tablet preparation had included uniformity size, weight variation, hardness, friability, disintegration and dissolution test. Conclusions: MSNDG had identical characteristics with Avicel PH 102 as excipient in tablet preparations by direct compression method.
PERBANDINGAN AKTIVITAS ANTIBAKTERI DAUN TEMPUH WIYANG (Emilia sonchifolia L.) DAN DAUN SITUDUH LANGIT (Erigeron sumatrensis Retz.) TERHADAP BAKTERI Propionibacterium acnes ATTC 1223
Authors: Herawati Irma Erika , Tristiyanti Deby , Kartikawati Endah 
Published: March 2024

Jerawat merupakan suatu keadaan inflamasi yang secara umum terjadi pada bagian kulit. Jerawat dapat disebabkan oleh bakteri Staphylococcus aureus, Propionibacterium acnes, dan Staphylococcus epidermidis. Penelitian ini bertujuan untuk mengetahui perbandingan aktivitas antibakteri dari ekstrak dan fraksi daun tempuh wiyang (Emilia sonchifolia L.) dan daun situduh langit (Erigeron sumatrensis Retz.) terhadap bakteri Propionibacterium acnes. Ekstraksi dilakukan dengan metode maserasi menggunakan pelarut etanol 70%. Pengujian aktivitas antibakteri dilakukan dengan metode difusi agar menggunakan cara sumuran. Hasil uji aktivitas antibakteri dianalisa dengan metode one way ANOVA yang dilanjutkan dengan uji Duncan. Dari hasil penelitian didapatkan bahwa baik ekstrak dan fraksi daun tempuh wiyang dan situduh langit memiliki aktivitas antibakteri terhadap bakteri penyebab jerawat P.acnes. Di mana ekstrak daun situduh langit memiliki kemampuan aktivitas antibakteri yang lebih baik dibandingkan dengan ekstrak daun tempuh wiyang.
Assessing recent recurrence after hepatectomy for hepatitis B-related hepatocellular carcinoma by a predictive model based on sarcopenia
Authors: Peng Hong , Lei Si-Yi , Fan Wei , Dai Yu , Zhang Yi , Chen Gen , Xiong Ting-Ting , Liu Tian-Zhao , Huang Yue , Wang Xiao-Feng , Xu Jin-Hui , Luo Xin-Hua 
Published: March 2024

BACKGROUND
Sarcopenia may be associated with hepatocellular carcinoma (HCC) following hepatectomy. But traditional single clinical variables are still insufficient to predict recurrence. We still lack effective prediction models for recent recurrence (time to recurrence < 2 years) after hepatectomy for HCC.
AIM
To establish an interventable prediction model to estimate recurrence-free survival (RFS) after hepatectomy for HCC based on sarcopenia.
METHODS
We retrospectively analyzed 283 hepatitis B-related HCC patients who underwent curative hepatectomy for the first time, and the skeletal muscle index at the third lumbar spine was measured by preoperative computed tomography. 94 of these patients were enrolled for external validation. Cox multivariate analysis was per-formed to identify the risk factors of postoperative recurrence in training cohort. A nomogram model was developed to predict the RFS of HCC patients, and its predictive performance was validated. The predictive efficacy of this model was evaluated using the receiver operating characteristic curve.
RESULTS
Multivariate analysis showed that sarcopenia [Hazard ratio(HR) = 1.767, 95%CI: 1.166-2.678, P < 0.05], alpha-fetoprotein ≥ 40 ng/mL (HR = 1.984, 95%CI: 1.307-3.011, P < 0.05), the maximum diameter of tumor > 5 cm (HR = 2.222, 95%CI: 1.285-3.842, P < 0.05), and hepatitis B virus DNA level ≥ 2000 IU/mL (HR = 2.1, 95%CI: 1.407-3.135, P < 0.05) were independent risk factors associated with postoperative recurrence of HCC. Based on the sarcopenia to assess the RFS model of hepatectomy with hepatitis B-related liver cancer disease (SAMD) was established combined with other the above risk factors. The area under the curve of the SAMD model was 0.782 (95%CI: 0.705-0.858) in the training cohort (sensitivity 81%, specificity 63%) and 0.773 (95%CI: 0.707-0.838) in the validation cohort. Besides, a SAMD score ≥ 110 was better to distinguish the high-risk group of postoperative recurrence of HCC.
CONCLUSION
Sarcopenia is associated with recent recurrence after hepatectomy for hepatitis B-related HCC. A nutritional status-based prediction model is first established for postoperative recurrence of hepatitis B-related HCC, which is superior to other models and contributes to prognosis prediction.
Comparison Study of Lignocaine-Bupivacaine with Normal Saline and Lignocaine-Bupivacaine Along with Fentanyl in Supraclavicular Brachial Plexus Block in Mid Arm Surgeries
Authors: Isha Yadav  
Published: March 2024

Background and Objective: brachial plexus block by supraclavicular approach achieve good motor, sensory
& sympathetic blocked in mid arm surgeries. Several adjuvants have been added to enhance effect of local
anaesthetic agent in peripheral nerve block. We performed a prospective randomized study to compare
lignocaine-bupivacaine with normal saline and lignocaine-bupivacaine along with fentanyl for onset, quality
& duration of block as well as post-operative analgesia.
Method: Randomized controlled study was carried act among 50 patients of either sex aged 20-50 asa grade
1 & 2 undergoing mid arm surgeries. patient was randomly divided in two groups. Group 1: 20ml of 0.5%
bupivacaine + 10ml of 2% lignocaine + 1 ml of normal saline Group 2: 20ml of 0.5% bupivacaine + 10ml
of 2% lignocaine + 1 ml of fentanyl (50 mcg)
Time taken for onset of sensory & motor as well as complete duration of block were noted in both groups.
Any complication during procedure during surgery as well as post operatively were noted & treated.
Result: Addition of fentanyl (50 mcg) to bupivacaine + lignocaine in peripheral nerve block cause early
onset for sensory block.
Mean duration of sensory blockade 440+/-62 in group 1 while 635+/-84 in group 2. mean duration of
analgesia 400+/-68 in group1 while 685+/-90 in group 2
It suggests that duration of sensory block and analgesia was prolonged in group 2
Conclusion: The addition of small-dose fentanyl to lignocaine solution in brachial plexus block can increase
the success rate and prolong the duration of analgesia, [16]with early onset time of sensory blockade as
compared with that achieved by the same doses of local anaesthetics used in combination.
PECULIARITIES OF FINANCING NATIONAL PROJECTS IN THE RUSSIAN FEDERATION
Authors: Родина Елена Евгеньевна , Имкинова Дарима Владимировна 
Published: March 2024

В настоящий момент возникают трудности в реализации национальных проектов. Однако, они являются комплексами мер с общенациональной значимостью, направленными на развитие государства и улучшение показателей. В России, национальные проекты поддерживаются президентом и правительством и включают направления “Экономический рост”, “Человеческий капитал” и “Комфортная среда для жизни”.
At the moment, there are difficulties in implementing national projects. However, they are sets of measures with national significance aimed at developing the state and improving indicators. In Russia, national projects are supported by the President and the government and include the areas of “Economic Growth”, “Human Capital” and “Comfortable living environment".
METHODS OF DETECTING AND PREVENTING FRAUD IN THE ECONOMIC SPHERE
Authors: Солдаткина Ольга Александровна , Рукопец Яна Александровна 
Published: March 2024

Статья посвящена исследованию актуальных вопросов мошенничества в экономической или финансовой сфере. Рассмотрено понятие «мошенничество», методы его выявления и предупреждения. В процессе исследования предложена обобщенная классификация мошенничества, выявлены проблемные вопросы в данной сфере и сформулированы рекомендации по их решению.
The article is devoted to the study of current issues of fraud in the economic or financial sphere. The concept of “fraud”, methods of its detection and prevention are considered. During the research, a generalized classification of fraud was proposed, problematic issues in this area were identified and recommendations were formulated for their solution.
MODERN ISSUES OF ACCOUNTING FOR INTANGIBLE ASSETS
Authors: Коробкова Оксана Константиновна 
Published: March 2024

В научной статье рассмотрены особенности применения Федерального стандарта по бухгалтерскому учёту 14/2022 «Нематериальные активы». Представлен анализ нововведений ФСБУ 14/2022 при организации учёта движения нематериальных активов и их оценки в бухгалтерском учёте.
The scientific article discusses the specifics of the application of the Federal Accounting Standard 14/2022 «Intangible assets». An analysis of the innovations of FSB 14/2022 in the organization of accounting for the movement of intangible assets and their valuation in accounting is presented.
ON THE ISSUE OF ECONOMIC SECURITY OF HOUSING AND COMMUNAL SERVICES ENTERPRISES
Authors: Рябинина Галина Михайловна , Коробкова Оксана Константиновна 
Published: March 2024

В научной статье рассмотрены современные вопросы экономической безопасности услуг предприятий жилищно-коммунальной сферы. Исследование внешней и внутренней среды предприятий жилищно-коммунального хозяйства показало некоторые предполагаемые угрозы экономической безопасности. Составлены меры по недопущению и погашению дебиторской задолженности перед управляющей компанией.
The scientific article examines the current issues of economic security of housing and communal services. A study of the external and internal environment of housing and communal services enterprises has revealed some alleged threats to economic security. Measures have been drawn up to prevent and repay accounts receivable to the management company.
Challenges in replication: Does amygdala gray matter volume relate to social network size?
Authors: McGugin Rankin W. , Roche Alexandra , Ma Jonathan , Gauthier Isabel 
Published: March 2024

AbstractIn this work, we tried to replicate and extend prior research on the relationship between social network size and the volume of the amygdala. We focused on the earliest evidence for this relationship (Bickart et al., Nature Neuroscience 14(2), 163–164, 2011) and another methodologically unique study that often is cited as a replication (Kanai et al., Proceedings of the Royal Society B: Biological Sciences, 279(1732), 1327–1334, 2012). Despite their tight link in the literature, we argue that Kanai et al. (Proceedings of the Royal Society B: Biological Sciences, 279(1732), 1327–1334, 2012) is not a replication of Bickart et al. Nature Neuroscience 14(2), 163–164 (2011), because it uses different morphometric measurements. We collected data from 128 participants on a 7-Tesla MRI and examined variations in gray matter volume (GMV) in the amygdala and its nuclei. We found inconclusive support for a correlation between measures of real-world social network and amygdala GMV, with small effect sizes and only anecdotal evidence for a positive relationship. We found support for the absence of a correlation between measures of online social network and amygdala GMV. We discuss different challenges faced in replication attempts for small effects, as initially reported in these two studies, and suggest that the results would be most helpful in the context of estimation and future meta-analytical efforts. Our findings underscore the value of a narrow approach in replication of brain-behavior relationships, one that is focused enough to investigate the specifics of what is measured. This approach can provide a complementary perspective to the more popular “thematic” alternative, in which conclusions are often broader but where conclusions may become disconnected from the evidence.
Copyright and sui generis protection of trained neural networks
Authors: TARASIUK А. 
Published: March 2024

The article provides a legal analysis of the possibility of copyright and sui generis protection of pre-trained (pre-taught) neural networks in their objective expression, taking into account new legislation, in particular, Law No. 2811-IX. The components of the trained neural network were analyzed in the context of their possible legal qualification as objects of copyright and sui generis in order to determine effective ways of protecting such objects both individually and as the trained neural network in general.
Covid-19 Pandemisinde Algılanan Stres Üzerine Nitel Bir Çalışma
Authors: Serim Yıldız Begüm , Üçok S. Burcu , Topcu Çiğdem , Chiarolanza Claudia , Randall Ashley K. 
Published: March 2024

2019 yılında Çin'de ilk koronavirüs vakasının görülmesinin ardından farklı ülkelerden vaka bildirimleri gelmiş ve bunun üzerine 2020 yılında Dünya Sağlık Örgütü pandemi ilan etmiştir. Bu süreçte sokağa çıkma yasağı, online çalışma, uzaktan eğitim gibi önlemler alınmış ve bu önlemlere ilişkin, kişilerin günlük yaşam alışkanlıkları ve birbirleriyle etkileşim kurma ve sürdürme şekilleri değişmiştir. Yaşanan değişikliklerin kişiler üzerinde stres gibi olumsuz sonuçlar doğurduğu alanyazın bulguları arasındadır. Bu araştırmanın amacı pandemi sürecinde yaşanan değişikliklere bağlı stres faktörlerini incelemektir.
Nitel araştırma deseni kullanılarak katılımcılara kendilerinin, birlikte yaşadıkları partnerlerinin ve toplumun yaşadığı stres deneyimlerine ilişkin sorular sorulmuştur. Çalışmanın örneklemi, yaşları 21 ile 71 arasında değişen 80’i kadın olmak üzere 103 kişiden oluşmuştur. Çevrimiçi bir form kullanılarak katılımcılara üç açık uçlu soru ile COVID-19 pandemisinde kendileri için, partnerleri için ve diğer insanlar için ne gibi stres kaynakları olduğunu düşündükleri sorulmuştur. Çerçeve analizi yöntemi ile incelenen veride kişinin kendisi, partneri ve diğer insanlar için ortaklaşan toplam dokuz ana tema ortaya çıkmıştır. Bunlar eğitim, iş/ekonomik, sağlık, sosyal ilişkiler, hijyen, günlük yaşamdaki değişiklikler, olumsuz duygular, olumlu deneyimler ve stresin olmamasıdır. Araştırmadan elde edilen sonuçların literatür ile uyumlu olduğu saptanmıştır. Pandeminin hem ülkemizde hem de dünyada ciddi bir kriz oluşturduğu aşikardır. Bu bağlamda bireylerin algıladıkları stres kaynaklarının tanımlanmasının koruyucu ve önleyici müdahalelerin planlanmasında yol gösterici olacağı düşünülmektedir.
The relationship between melatonin level, oxidative stress, fatigue and sleep disorders in multiple sclerosis patients
Authors: Dağcı Yıldız , Bilge Nuray , Ceylan Mustafa , Özkan Halil İbrahim 
Published: March 2024

Aims: Our study aimed to investigate the relationship between oxidative stress and melatonin levels, sleep disturbances and fatigue in persons with MS (pwMS).
Methods: The study included 50 pwMS and 30 healthy controls. Levels of serum melatonin, glutathione peroxidase (GPx), superoxide dismutase (SOD), and malondialdehyde (MDA) were measured in both groups. Persons with MS (pwMS) were evaluated using the extended disability status scale (EDDS) while Pittsburgh sleep quality index (PSQI), Epworth sleepiness scale, insomnia severity index, fatigue severity scale and Beck depression scale were used for both groups.
Results: Persons with MS (pwMS) exhibited significantly higher sleep disturbances (p
A biomarker for estimating no-reflow phenomenon in PCI-treated non-ST-segment elevation myocardial infarction patients: serum Cystatin C
Authors: Genç Ömer , Yıldırım Abdullah , Erdoğan Aslan 
Published: March 2024

Aims: Cystatin C (Cys-C) is a biochemical marker associated not only with renal function but also with inflammatory processes. We aimed to investigate the relationship between the post-percutaneous coronary intervention (PCI) no-reflow phenomenon (NRP) and Cys-C in patients with non-ST-segment elevation acute coronary syndrome (NST-ACS).
Methods: This retrospective, single-center observational study consecutively enrolled patients who were hospitalized with a diagnosis of NST-ACS and underwent PCI between October 2021 and February 2022. Baseline characteristics, medications, admission laboratory parameters, and angiographic features were recorded. Logistic regression and sensitivity analyses were performed to identify parameters associated with NRP.
Results: Out of 199 patients (mean age: 62.0±10.3, 59.8% male), 36 (18.1%) developed NRP. Patients who developed NRP had a lower ejection fraction (49.7±10.3% vs. 53.5±7.1%, p=0.046) and were less likely to be male (36.1% vs. 65.0%, p=0.001). Additionally, individuals with NRP exhibited higher blood urea and C-reactive protein levels than those without NRP (p1.1 mg/L for Cys-C determined NRP with 72.2% sensitivity and 66.9% specificity (area under the curve=0.711, p