bluuebunny/crossref_metadata_2025_split huggingface dataset:
Multilocular cyst of the kidney: A case report
Authors: Eisenkraft Shimon , Englander Lenore , Wolf Richard M. , Huben Robert P. , Pontes J. Edson 
Published: February 2007

AbstractA 69‐year‐old female was referred to Roswell Park Memorial Institute for management of a right hdney tumor. Her evaluation included excretory urography, ultrasound, computerized axial tomography (CT scan), and selective renal angiography. Fine needle aspiration cytology was felt to be consistent with primary renal cell carcinoma. In spite of the radiological appearance of a benign lesion, a right radical nephrectomy was performed because of the positive cytology on fine needle aspiration. The pathological diagnosis was a solitary multilocular cyst of the kidney.
Treatment of superficial bladder tumors in a controlled trial with Thio‐TEPA versus adriamycin
Authors: Horn Yoav , Eidelman Abraham , Walach Natalio , Yuval Eliahou , Markowitz Amira 
Published: February 2007

AbstractForty‐six patients with superficial transitional cell carcinoma of the bladder were randomized into two groups. Thio‐TEPA or adriamycin were instilled periodically into the bladder and cystoscopic follow up was carried out. Both thio‐TEPA and adriamycin proved to have similar efficacy in delaying tumor recurrence. Further investigations to establish better dose and interval schedules are indicated.
Obstructive jaundice caused by hepatocellular carcinoma
Authors: Joehl Raymond J. , Abt Arthur B. 
Published: February 2007

AbstractHepatocellular carcinoma can be complicated by obstructive jaundice with tumor growing into the extrahepatic bile duct. This complication is an autopsy finding in most reported cases and, rarely, is recognized ante mortem. We report two patients with hepatocellular carcinoma who presented initially with obstructive jaundice. Clotted blood and tumor, which caused bile duct obstruction, was removed operatively and the biliary tract was drained in both patients. We conclude that 1) blood clot and fleshy debris removed from the common bile duct at operation for obstructive jaundice suggests the possibility of hepatocellular carcinoma; 2) the differential diagnosis of jaundice and fever in patients known to have hepatocellular carcinoma should include intrabiliary tumor causing obstruction and cholangitis; and 3) the association of obstructive jaundice and hepatocellular carcinoma may occur more often than previously recognized.
Fibromyxomatous pseudotumor of the scrotum
Authors: Sarma Deba P. , Weilbaecher Thomas G. , Wiener Marshall 
Published: February 2007

AbstractAn unusual scrotal mass occurring in a 72‐year‐old man is described. Clinically and grossly, the lesion appeared to be a neoplasm. However, microscopically the mass was composed of fibromyxomatous tissue that appeared to be degenerative rather than neoplastic in nature.
Blood transfusion and disease‐free survival in carcinoma of the breast
Authors: Nowak Michael M. , Ponsky Jeffrey L. 
Published: February 2007

AbstractA retrospective study was undertaken to determine the effect of perioperative blood transfusion on disease‐free survival rates in patients with carcinoma of the breast. The charts of 81 patients participating in a NSABP breast cancer protocol at The Mt. Sinai Medical Center, Cleveland, Ohio, were reviewed. There was no statistically significant difference in disease‐free survival between those patients receiving blood transfusions and those that did not when considering the entire group of patients or subgroups based upon age, nodal status, estrogen receptor status, or progesterone receptor status. However, the subgroup of patients receiving tamoxifen chemotherapy, especially those with positive estrogen receptors, had significantly reduced disease‐free survival (P < .05) when given blood transfusions. These results suggest an adverse effect of blood transfusion on disease‐free survival in breast cancer patients treated with tamoxifen chemotherapy.
The role of post‐operative radiation therapy in the treatment of malignant tumors of the parotid gland
Authors: Imperato Joseph P. , Weichselbaum Ralph R. , Ervin Thomas J. 
Published: February 2007

AbstractTwenty‐nine patients treated with postoperative radiotherapy for malignant tumors of the parotid gland were reviewed at the Joint Center for Radiation Therapy. Most patients were treated between 5,000 and 6,500 rad. All were treated because of microscopic residual disease, extra capsular extension, or tumor close to the facial nerve. The overall results showed one in‐field failure, two marginal recurrences, and eight patients failed distantly. Poor prognostic factors included high‐grade, extracapsular extension, and nodal involvement. We conclude that patients with malignant tumors of the parotid should be treated with postoperative radiation therapy if any of the bad prognostic signs are present. This may enable the surgeon to spare the facial nerve and obtain local control results equal to or better than more radical surgical procedures.
Tissue effects of neodymium: Yag laser photo‐radiation of canine ureters
Authors: Smith Joseph A. , Lee Randall G. , Dixon John A. 
Published: February 2007

AbstractAlthough the entire ureter and renal collecting system are accessible for endoscopic treatment with a neodymium:YAG, (Nd:YAG) laser, specifications for safe laser application within the ureter are not established. After various doses of Nd:YAG laser energy were delivered, the midureters of six mongrel dogs were studied to determine tissue effects. Doses which are appropriate within the bladder (35 watts × 2 seconds) resulted in perforation and urine leak from the ureters. Higher doses (60‐65 watts) of short duration were tolerated without problems and nonstrictured healing ensued. Further studies are necesssary before Nd:YAG laser treatment of mid‐ureteral tumors is recommended.
Immune capability of rats with colorectal carcinoma treated by resection with or without 5‐fluorouracil or levamisole
Authors: House A. K. , Maley M. A. L. 
Published: February 2007

AbstractThe immune status of rats with chemically induced colorectal tumors was investigated for 8 weeks following treatment by resection, resection plus 5‐fluorouracil (5‐FU), and resection plus levamisole. Normal rats without tumors were given identical treatment and acted as controls.Tumor rats regained their ability to respond to an allograft of allogeneic lymphocytes after surgical excision of the tumor for a short period. Adjuvant Levamisole treatment enhanced this responsiveness, but adjuvant 5‐FU depressed it.The spleen and lymph node cells of tumor‐bearing rats showed greater spontaneous and PHA‐induced cytotoxicity for chicken red blood cells than control rats (P<0.001), and adjuvant therapy did not alter this response. However in control animals, levamisole treatment did augment the antibody‐dependent cytotoxicity of their spleen and lymph node cells. Rats receiving tumor resection alone were immune by leukocyte migration inhibition at 8 weeks only, while those receiving either adjuvant exhibited an immune response to the same homogenate for 4 and 8 weeks.
Scalp metastases as the initial presentation of malignant fibrous histiocytoma
Authors: Chen Karl T. K. 
Published: February 2007

AbstractA rare case of malignant fibrous histiocytoma of the retroperitoneum with scalp metastases as the initial presentation is described. The scalp lesions were mistaken for atypical schwannomas, however subsequent investigation revealed a large retroperitoneal tumor and multiple hepatic and pulmonary metastases.
Partial colon resection as a promotor of cancer growth in the rat
Authors: Rubio C. A. , Nylander G. , Wallin B. , Sveander M. , Alun M.‐L. , Duvander A. 
Published: February 2007

AbstractSprague‐Dawley rats were treated with dimethylhydrazine (DMH) once a week for three months. After a treatment‐free period of five months, they were subjected to minimal colon resection with an end‐to‐end anastomosis. Autopsy (one year after the discontinuation of DMH treatment, and seven months after surgery) demonstrated anastomotic tumors in 50% of the animals. Conclusions were that the carcinogen had induced genetic changes in the nonmigrating stem cells in the colonic crypts and that the chronic reparative process resulting from surgical trauma may have promoted colonic cells to induce tumors at the suture line.
Squamous carcinoma arising in a pilonidal sinus
Authors: Lineaweaver W. C. , Brunson M. B. , Smith J. F. , Franzini D. A. , Rumley T. O. 
Published: February 2007

AbstractA patient with squamous cell carcinoma arising from an extensive pilonidal sinus was treated with wide local excision, resulting in an apparent cure over a 1‐year follow‐up period. Review of the literature revealed 32 previously reported cases of this entity. Forty‐four percent of these patients developed recurrences or metastases, and 22% died of their disease. The largest historical treatment group with at least 1‐year follow‐up (19 patients with localized disease) underwent wide excision. Forty‐two percent of these patients recurred or developed metastases. Ultimately, 89.5% of these patients were reported cured, but only five survivors were followed for as long as 5 years. Historical experience appears to identify pilonidal tract squamous carcinoma as an aggressive tumor. The reported success of wide local excision is based on a small number of patients followed for short periods of time. Continued experience with this disease should be reported to verify the adequacy of local excision or identify the need for adjunctive therapy.
A complication of the implantable constant infusion chemotherapy pump
Authors: Pietrafitta Joseph J. 
Published: February 2007

AbstractThe treatment of metastatic colorectal cancer to the liver has been a significant problem for clinicians in the past. Recent technical advances in infusion systems in the form of the infusaid pump has allowed delivery of chemotherapeutic agents to the liver with great reliability. As more chemotherapy pumps are implanted, undoubtedly, new and unusual complications will occur. This report centers on a patient who developed a disrupted catheter secondary to a high pressure side port injection. It includes a description of the complication, how it occurred, was recognized, and corrected. This report will, hopefully, save other clinicians from encountering similar complications in any of their patients.
Veno‐occlusive liver disease after dacarbazine therapy (DTIC) for melanoma
Authors: Erichsen Christian , Jönsson Per‐Ebbe 
Published: February 2007

AbstractA case of veno‐occlusive disease of the liver with fatal outcome after dacarbazine (DTIC) therapy for melanoma is reported. There was a fulminant clinical course from start of symptoms until death. At autopsy the liver was enlarged and firm with signs of venous congestion. Small and medium‐sized hepatic veins were blocked by thrombosis. Eosinophilic infiltrations were found around the vessels. Published cases from the literature are reviewed and pertinent features discussed.
Ovarian androblastoma metastatic to tonsil
Authors: Bychkov Vladimir , Ghosh Luna , Lundine Mark , Manaligod Jose R. , McQuire William P. , Rose Christopher 
Published: February 2007

AbstractStructural pattern of a tonsillar tumor found in a 67‐year‐old female was similar to a small ovarian androblastoma diagnosed histologically 61/2 years earlier. Electron microscopic study of the tonsillar mass revealed crystalloid structures suggestive of the Leydig cell origin of the tumor. After tonsillectomy, there was no local recurrence of the tumor, but the patient died a year later of multiple metastases. There appeared to be no previous reports of ovarian tumors metastatic to tonsil, and malignant androblastomas of the Leydig cell type are extremely rare.
Radiation therapy of seminoma of the testis
Authors: Jose Baby , Lee Perkins P. , Kays Howard , Chu Ann M. , Sharma Subhash C. 
Published: February 2007

AbstractThis study is a review of 66 patients with a diagnosis of testicular seminoma, treated at the Department of Radiation Oncology, University of Louisville, from 1959 to 1978. Sixty‐four of the patients were diagnosed as pure seminomas and two as spermatocytic type. The age of the patients ranged from 16 to 75 years with a median of 39. Fifty‐four patients (82%) presented with swelling or mass in the testis, 7 patients with pain, 1 patient with hydrocele, and 4 patients had seminoma diagnosed incidentally. The distribution was equal for both right and left sides. There were 39 (59%) and 27 (41%) patients in stages I and II, respectively. All stage I patients received only infradiaphragmatic irradiation by a “hockey stick” field, and the majority of them received a dose of 3,200 – 3,600 rads in 3–4 weeks time. Stage II patients received elective irradiation to the mediastinum and neck region, in addition to the infradiaphragmatic irradiation. The 5‐year actuarial survival rates for stage I and II seminomas are 96% and 92%, respectively. There were no serious complications during follow‐up. The role of elective irradiation in stage I disease is discussed with a brief review of the literature.
Relationship between lymphocytic cytotoxicity and phytohemagglutinin‐lnduced lymphoblastogenesis before and after surgical tumor excision: An experimental study
Authors: Yamamoto Satoru , Sakata Kazuki , Kunieda Tokuro , Saji Shigetoyo , Tanemura Hiromi , Takekoshi Tomoharu , Sugiyama Yasuyuki 
Published: February 2007

AbstractExperimental study was performed on changes in lymphocytic cytotoxicity and phytohemagglutinin (PHA)‐lymphoblastogenesis after surgical tumor excision and on a possibility of estimating antitumor immunocompetence based on the latter parameter, using 3‐methyl‐cholanthrene‐induced mammary cancer, MRMT‐1, of SD rats. When the tumor was excised at 2 weeks after inoculation, cytotoxicity showed, after a transient rise, a marked reduction at 4 weeks postoperatively in the cases of postoperative negative metastasis, while it showed a high peak at 3 weeks postoperatively, followed by a sharp descent, in the cases of postoperative positive metastasis. On the other hand, PHA‐lymphoblastogenesis was found to recover a relatively high level postoperatively, in the cases of both negative and positive metastases. It appears to be difficult to estimate specific cytotoxicity from PHA‐blastogenesis, but both are useful, in complementary fashion, to estimate the antitumor immunocompetence.
Analysis of pancreatoduodenectomy
Authors: O'Brien Paul H. , Mincey Kenneth H. 
Published: February 2007

AbstractBetween 1956 and 1982, there were 55 pancreatoduodenectomies performed at the Medical University of South Carolina by 19 different surgeons. There were 26 resections for adenocarcinoma of the head of the pancreas and 16 resections for carcinoma of the ampulla of vater, carcinoma of the extrahepatic biliary ducts, and carcinoma of the duodenum. There were seven resections for chronic pancreatitis. There were two resections for trauma and three resections in the (1960s) for carcinoma of the stomach. There was one resection for cystadenocarcinoma of the pancreas. In the patients with carcinoma of the pancreas, resection was only performed when there was no gross evidence of extension beyond the parenchyma of the pancreas. Analysis of the resected specimen revealed 44% of the pancreatic carcinomas subsequently had positive lymph nodes. None of these patients became long‐term survivors. Failure of the pancreato‐jejunostomy was the most serious complication, occurring in 7 of 55 resections. There were no fistulas where a muscosal to mucosal anastamosis was performed to join the pancreas with the jejunum. The five‐year survival for all patients with carcinoma of the pancreas was 11.6%. The 3 five‐year survivors were from resections performed between 1956 and 1970. During these years, the mortality rate for the procedure was 21%. From 1970 to 1982 there were no five‐year survivors from carcinoma of the pancreas. However, the mortality rate was 10.6%. The history and current controversies over this surgical procedure are reviewed.
The mortality rate from lung metastases in animals inhaling nitrogen dioxide (NO2)
Authors: Richters Arnis , Richters Valda , Alley Wayne P. 
Published: February 2007

AbstractA study was carried out to determine the interrelationship between the inhalation of nitrogen dioxide (0.4 ± 0.50 ppm), lung metastases development from circulating cancer cells, and death rate from such metastases. C57 BL/6J mice were used in these experiments. Animals were divided into control and NO2‐exposed groups, and were exposed to filtered air and 0.4 ppm of NO2, respectively. Following 12 weeks of exposure, all animals were infused intravenously with syngeneic, viable B16 melanoma cells. The results indicate that a subpopulation of NO2‐exposed animals showed a significant increase in mortality rate during the early part of the experiment. The interpretation is that animals especially sensitive to the NO2 insult developed extensive metastases at an early stage. The question raised is whether or not the progression of human cancer is influenced by the inhalation of noxious pollutants in the ambient atmosphere.
Desmoid tumor—review and follow‐up of ten cases
Authors: Shpitz Baruch , Siecal Annette , Witz Misha , Kaufman Zvi , Dinbar Alex 
Published: February 2007

AbstractTen cases of desmoid tumor, diagnosed, treated, and followed during the past 11 years, were reviewed and the patients reexamined. Two were up to 3 years, two up to 5 years, and four up to 11 years after excision. The remaining two patients were lost to follow‐up. The 10 patients included one male and nine females; six females were of childbearing age and three were postmenopausal. In four females the desmoid tumor was located near various surgical scars. In the one recurrent desmoid it was most probably related to both repeated traumatization of the abdominal wall due to pregnancies and hyperestrogenism. All the surgical margins of resection were microscopically involved by the process. An open liver biopsy, performed simultaneously with the excision of the recurrent desmoid, showed benign nodular hyperplasia compatible with hyperestrogenism. Estrogen and progesterone receptors of this desmoid were negative. In this present series follow‐up revealed, in contrast to general agreement, that in spite of incomplete excision, the recurrence rate was low. We suggest that the surgical approach to desmoid tumors could be less radical, except possibly for lesions in patients with multiple causative factors.
Multidisciplinary pretreatment cancer planning. The Roswell park memorial lecture, march 21, 1984, Roswell park memorial institute, Buffalo, New York
Authors: Moore Condict 
Published: February 2007

AbstractOne can estimate that 60% or more of cancer patients stand to benefit from the multidisciplinary treatment of cancer. Different treatments given in sequence mean real benefit in terms of absolute cure or length of disease‐free life for many. While the details of treatment techniques can usually be worked out for each patient in expert fashion, the process of planning to fit the three main modalities together into a single plan presents complex problems. To obtain optimum results someone must assemble and coordinate the opinions of the oncologists who are consulted in each case; and someone must do it before treatment begins. Benefit is significantly reduced if the planning process is delayed until recurrence occurs. Those who act as primary physicians in caring for cancer patients have a newly defined major role to play: they must select the oncology team, coordinate the various opinions, and continue to supervise the course of the cancer throughout in order that the patients receive the best care. When a physician prepares for, and accepts, this role of leader‐coordinator, and outlines in broad general terms a properly integrated plan from the first, details of therapy fall easily into place.
A reevaluation of bone scans in breast cancer
Authors: Bradley Hayward R. , Frazier Thomas G. 
Published: February 2007

AbstractA retrospective analysis of 151 patients with breast cancer over 2 years was performed to assess laboratory values as predictors of metastatic disease demonstrated by technecium‐99 bone scan. In 105 patients with normal alkaline phosphatase (AP) and lactate dehydrogenase (LDH) values, only one positive bone scan (0.95%) was obtained. If either the AP or LDH value was abnormal, 15 of 29 scans (51.7%) were positive. If both values were abnormal, six of nine patients (66.7%) had positive bone scans. Of 41 patients with either an elevated AP or LDH, 26 (63.4%) were shown to have metastatic breast disease. In our subgroup of 120 consecutive admissions for primary evaluation and treatment of breast cancer, the 95 patients with normal AP and LDH values had 41 negative bone scans and no evidence of distant metastases in any patient. According to these results, we recommend that breast cancer metastatic screening be done by alkaline phosphatase and LDH determinations, and that isotope scans should be reserved for those patients having normal values or symptoms that suggest metastases.
Quality of life after breast cancer surgery
Authors: De Haes J. C. J. M. , Welvaart K. 
Published: February 2007

AbstractAll patients (N=41) who participated in a randomized clinical trial in the Leiden University Hospital comparing mastectomy to tumorectomy have been studied with respect to their quality of life 11 months (± 5) after surgery. The body image of patients is more severely impaired after mastectomy than after tumorectomy (P < .01).The studied groups did not differ, as has been suggested, with respect to fear of recurrence and death. These fears, however, turned out to be inversely related to the age of the patients (r = ‐.34, P = .02).
Multimodal approach in the therapy of stage III female breast cancers
Authors: Shanta V. , Krishnamurthi S. , Sastry D. V. L. N. , Menon Ranjini 
Published: February 2007

AbstractOne thousand thirty‐seven female breast cancers were treated at the Cancer Institute (WIA), Madras, between 1965 and 1978. Five hundred twenty‐one of them (ie, just over 50%) were in stage III, with extensive local disease, unsuitable for surgery ab initio. Four hundred twelve of them (group A) received radiation therapy (RT) initially and 109 (group B) a combination of radiation and chemotherapy (CT). In 68% of the former and 77% of the latter the tumours became resectable after this preliminary treatment. Radical mastectomy in group A and Patey's mastectomy in group B were performed. The material in these two groups was similar. The five‐year survival NED in group A was 45%, and in group B 64.61%. Adequate surgery following RT and CT seemed essential to improve survival. The impact of added chemotherapy (CT) was mainly felt in the node‐positive cases.