bluuebunny/crossref_metadata_2025_split huggingface dataset:
Focus on the potential of hybrid hard‐ and soft‐MCR–ALS in time resolved spectroscopy
Authors: Blanchet Lionel , Ruckebusch Cyril , Huvenne Jean‐Pierre , de Juan Anna 
Published: July 2008

AbstractThis work presents some strategies to obtain time‐dependent concentration profiles and spectra from time resolved spectroscopic data of complex systems. Multivariate curve resolution–alternating least squares (MCR–ALS) has been of particular interest in this field because of the possibility to implement simultaneously soft‐modeling constraints and kinetic models on a multibatch resolution. This approach allows circumventing a rank deficiency inherent to time resolved difference data, even in presence of interferent species. The methodology is illustrated using examples from femtosecond photochemistry and biochemistry. Copyright © 2008 John Wiley & Sons, Ltd.
Estimation of drug release profiles of a heterogeneous set of drugs from a hydrophobic matrix tablet using molecular descriptors
Authors: Matero Sanni , Reinikainen Satu‐Pia , Lahtela‐Kakkonen Maija , Korhonen Ossi , Ketolainen Jarkko , Poso Antti 
Published: July 2008

AbstractWe utilized a diverse set of drug compounds in order to quantitatively model and predict the drug release profiles of the compounds from starch acetate matrix tablets. The set of drug molecules used represented a wide spectrum of physicochemically different drugs which are administered perorally. The molecular descriptors that characterize the properties of dissolved drugs were evaluated as variables describing the dissolution profiles. The molecular descriptors revealed potential in predicting the dissolution profiles of test drugs, e.g., the molecular level interactions between drug, solvent, and excipient. This method could be utilized as a process control or a development tool in the pharmaceutical industry, e.g., to provide information about drug dissolution behavior in early formulation studies and in testing the similarity of tablets in different batches. Copyright © 2008 John Wiley & Sons, Ltd.
Dependence of Enantioselectivity on the Ligand/Metal Ratio in the Asymmetric Michael Addition of Indole to Benzylidene Malonates: Electronic Influence of Substrates
Authors: Schätz Alexander , Rasappan Ramesh , Hager Markus , Gissibl Anja , Reiser Oliver 
Published: July 2008

AbstractSimple bis(oxazoline) ligands, especially azabis(oxazolines), can promote the copper(II)‐catalyzed Michael addition of indoles to benzylidene malonates with up to >99 % ee (ee=enantiomeric excess), provided that the ligand/metal ratio is tuned meticulously with particular regard to the electronic properties of the substrate. Despite a common paradigm followed in many asymmetric catalyses, an excess of chiral ligand is not always beneficial. In fact any excess of ligand has to be avoided to reach excellent enantioselectivities when electron‐rich benzylidene malonates are used. On the contrary, malonates carrying an electron‐withdrawing group require an excess of ligand for an optimum ee value. A correlation of optical yields versus the σI values of several para substituents shows a sigmoid trajectory. In the presence of an additive, such as triflate, the significance of the ligand/metal ratio vanishes and very good enantioselectivities are achieved at any rate—no matter whether electron‐donating or withdrawing substituents are present.
A Combined Experimental and Theoretical Study of the Molecular Inclusion of Organometallic Sandwich Complexes in a Cavitand Receptor
Authors: Zuidema Erik , Sarmentero M. Angeles , Bo Carles , Ballester Pablo 
Published: July 2008

AbstractWe describe herein a detailed study of the inclusion processes of several positively charged organometallic sandwich complexes inside the aromatic cavity of the self‐folding octaamide cavitand 1. In all cases, the binding process produces aggregates with a simple 1:1 stoichiometry. The resulting inclusion complexes are not only thermodynamically stable, but also kinetically stable on the 1H NMR spectroscopy timescale. The binding constants for the inclusion complexes were determined by different titration techniques. We have also investigated the kinetics of the binding process and the motion of the metallocenes included in the aromatic cavity of the host. Using DFT‐based calculations, we have evaluated the energies of a diverse range of potential binding geometries for the complexes. We then computed the proton chemical shifts of the included guest in each one of the binding geometries. The agreement between the averaged computed values and the experimentally determined chemical shifts clearly supports the proposed binding geometries that we assigned to the inclusion complexes formed in solution. The combination of experimental and theoretical results has allowed us to elucidate the origins of the distinct features detected in the complexation process of the different guests, as well as their different motions inside the host.
Glycomimetics and Glycodendrimers as High Affinity Microbial Anti‐adhesins
Authors: Imberty Anne , Chabre Yoann M. , Roy René 
Published: July 2008

AbstractAdhesion to epithelial surface is often the first step in bacterial and viral infection. In this process, the microbes use a variety of proteins for interaction with host carbohydrates presented as glycoconjugates on cell surfaces. Crystal structures of adhesin and lectin binding sites in complexes with oligosaccharide open the route for design and synthesis of glycomimetics, glycodendrimers, and glycopolymers that are able to block infection at an early stage.
Nematic and Columnar Ordering of a PEG–Peptide Conjugate in Aqueous Solution
Authors: Hamley Ian W. , Krysmann Marta J. , Kelarakis Antonios , Castelletto Valeria , Noirez Laurence , Hule Rohan A. , Pochan Darrin J. 
Published: July 2008

AbstractThe self‐assembly in aqueous solution of a PEG–peptide conjugate is studied by spectroscopy, electron microscopy, rheology and small‐angle X‐ray and neutron scattering (SAXS and SANS). The peptide fragment, FFKLVFF is based on fragment KLVFF of the amyloid β‐peptide, Aβ(16–20), extended by two hydrophobic phenylalanine units. This is conjugated to PEG which confers water solubility and leads to distinct self‐assembled structures. Small‐angle scattering reveals the formation of cylindrical fibrils comprising a peptide core and PEG corona. This constrained structure leads to a model parallel β‐sheet self‐assembled structure with a radial arrangement of β sheets. On increasing concentration, successively nematic and hexagonal columnar phases are formed. The flow‐induced alignment of both structures was studied in situ by SANS using a Couette cell. Shear‐induced alignment is responsible for the shear thinning behaviour observed by dynamic shear rheometry. Incomplete recovery of moduli after cessation of shear is consistent with the observation from SANS of retained orientation in the sample.
ChemInform Abstract: Copper‐Catalyzed Addition of Halide and Sulfide Groups to Alkynes Utilizing Disulfides with Tetrabutylammonium Halides.
Authors: Taniguchi Nobukazu 
Published: July 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Preparation of Phenyl‐butyraldehydes Using a Base‐Catalyzed Aromatization of Dienones.
Authors: Plano Maria Fernanda , Labadie Guillermo R. , Cravero Raquel M. 
Published: July 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Mannich‐Type Reaction Catalyzed by Silica‐Supported Fluoroboric Acid under Solvent‐Free Conditions.
Authors: Chen WeiYi , Li XinSheng , Lu Jun 
Published: July 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Facile Synthesis of 9,10‐Diarylphenanthrenes and Poly(9,10‐diarylphenanthrene)s.
Authors: He Bo , Tian Hongkun , Geng Yanhou , Wang Fosong , Muellen Klaus 
Published: July 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis of NH‐Aziridines from Vicinal Amino Alcohols via the Wenker Reaction: Scope and Limitation.
Authors: Zhu Min , Hu Libo , Chen Ning , Du Da‐Ming , Xu Jiaxi 
Published: July 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Sulfamic Acid as a Novel, Efficient, Cost‐Effective, and Reusable Solid Acid Catalyst for the Synthesis of Pyrroles under Solvent‐Free Conditions.
Authors: De Surya K. 
Published: July 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis of Fused 4,5‐Disubstituted Indole Ring Systems by Intramolecular Friedel—Crafts Acylation of 4‐Substituted Indoles.
Authors: Fillion Eric , Dumas Aaron M. 
Published: July 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Preparation of 4,5‐Dihydronaphth[2,1‐c]isoxazoles from Dilithiated 2‐Tetralone Oxime and Select Esters.
Authors: Choi Emily , Knight John D. , Malatanos Maria D. , Rhett J. Matthew , Walters Matthews J. , Dunn S. Patrick , Beam Charles F. 
Published: July 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Palladium‐Catalyzed Direct Arylations of 1,2,3‐Triazoles with Aryl Chlorides Using Conventional Heating.
Authors: Ackermann Lutz , Vicente Ruben , Born Robert 
Published: July 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Simple and Facile Synthesis of Tetralone‐spiro‐glutarimides and Spiro‐bisglutarimides from Baylis—Hillman Acetates.
Authors: Basavaiah Deevi , Reddy Raju Jannapu 
Published: July 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis and Reactivity of 3‐Amino‐9‐methoxymethyl‐7‐methyl‐3,4‐dihydropyrido[3′,2′:4,5]thieno [3,2‐d]pyrimidin‐4‐ones.
Authors: Kostenko E. S. , Lipunov M. M. , Kaigorodova E. A. , Konyushkin L. D. 
Published: July 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis, Structure and Spectral Study of Two Types of Novel Fluorescent BF2 Complexes with Heterocyclic 1,3‐Enaminoketone Ligands.
Authors: Xia Min , Wu Bin , Xiang Guofeng 
Published: July 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis and Characterization of Dibenzodioxazasiladecines.
Authors: Singh M. S. , Singh Pratibha 
Published: July 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: A Facile Synthesis of Chiral 4‐(tert‐Butylsulfinylamino)‐2‐oxophosphonates and Their Conversion into 5,5‐Disubstituted 2‐Benzylidene‐3‐oxopyrrolidines.
Authors: Chen Qianyi , Yuan Chengye 
Published: July 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Phanginin A—K, Diterpenoids from the Seeds of Caesalpinia sappan Linn.
Authors: Yodsaoue Orapun , Cheenpracha Sarot , Karalai Chatchanok , Ponglimanont Chanita , Chatrapromma Suchada , Fun Hoong‐Kun , Kanjana‐Opas Akkharawit 
Published: July 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Withangulatin I, a New Cytotoxic Withanolide from Physalis angulata.
Authors: Lee Shwu‐Woan , Pan Min‐Hsiung , Chen Chiu‐Ming , Chen Zong‐Tsi 
Published: July 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: G‐Quadruplexes: Targets in Anticancer Drug Design
Authors: Ou Tian‐miao , Lu Yu‐jing , Tan Jia‐heng , Huang Zhi‐shu , Wong Kwok‐Yin , Gu Lian‐quan 
Published: July 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis of Pharmaceutically Active Compounds Containing a Disubstituted Piperidine Framework.
Authors: Kaellstroem Sara , Leino Reko 
Published: July 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: The Use of Silicon‐Based Tethers for the Pauson—Khand Reaction
Authors: Dobbs Adrian P. , Miller Ian J. , Martinovic Sasa 
Published: July 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis and Elaboration of trans 2,3‐Diaryloxiranes
Authors: Bonini Carlo , Lupattelli Paolo 
Published: July 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Imidoylation Reactions at Carbon
Authors: Katritzky Alan R. , Khashab Niveen M. , Todadze Ekaterina 
Published: July 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Recent Advances and Trends in Reactive Polyurethane Adhesives
Authors: Krebs Michael 
Published: July 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
A Method to Determine the Transfer of Mycotoxins from Materials to Air
Authors: Moularat Stephane , Robine Enric 
Published: July 2008

AbstractThe aim of this work was to propose a new methodological approach to enable the measurement of three airborne mycotoxins and thus determine directly the rate of production and physical characteristics of these aerosols. A method enabling the measurement of three major mycotoxins in indoor air (sterigmatocystin (ST), deoxynivalenol (DON), and ochratoxin A (OA)) was thus optimized. This assay method was able to identify and quantify these mycotoxins at respective concentrations of 30 μg/L (n = 30, σ/m = 3.9%), 20 μg/L (n = 10, σ/m = 5.5%), and 20 μg/L (n = 10, σ/m = 7.6%). Using this analytical technique and a rotary cup collection system validated elsewhere, measurement of the concentrations of three airborne mycotoxins was made possible with a theoretical limit of quantification (LOQ) of 60 pg/m3 of air. Study of the transfer of mycotoxins from a substrate to the air made it possible to demonstrate, firstly, that the quantity of aerosolized mycotoxins was not proportional to that present on the moldy materials, and secondly that mycotoxins can be transported by aerosols in the alveolar fraction. We determined, under these conditions, a rate of production of ST aerosols.
Retention of Inactivated Bioaerosols and Ethene in a Rotating Bioreactor Constructed for Bioaerosol Activity Studies
Authors: Krumins Valdis , Son Eun‐Kyeu , Mainelis Gediminas , Fennell Donna E. 
Published: July 2008

AbstractAvailable literature raises the possibility that airborne microorganisms are not just passively transported through the air, but may be metabolically active while “in transit”. To investigate the metabolic activity of bacteria suspended in air enriched with volatile growth substrates, a rotating bioreactor system was developed and tested which allows prolonged suspension of bacteria in air. The bioreactors were 0.32 m3 stainless steel drums rotated at 1.3 revolutions per minute and equipped with on‐board pressure, temperature and humidity transducers with real‐time data collection. Bioreactors were tested for retention of a volatile organic compound, ethene, and for suspension of an inactivated laboratory‐generated Pseudomonas fluorescens bioaerosol. At an initial ethene concentration of 560 ppmv the first order abiotic loss of ethene was 0.051 ± 0.010 d–1 (average ± standard deviation) or a half life of 13.6 days. Inactivated airborne bacteria (size mode 0.5 to 0.7 μm) remained suspended with a half life of 8.5 days. Thus, the bioreactors maintained bacteria suspended in the presence of a volatile growth substrate for a time period theoretically sufficient to observe metabolic activity. Bioreactors will be used to test natural bioaerosols and active laboratory‐generated bioaerosols during enrichment with volatile organic compounds to assess growth and substrate biodegradation.
A design of permanent magnet array for unilateral NMR device
Authors: Kato Hirokazu , Kishi Kanji , Takahashi Norio , Asaumi Jun‐Ichi , Honda Yasutoshi , Yanagi Yoshinobu , Aoki Masaaki 
Published: July 2008

AbstractWe have designed a three‐dimensional magnetic circuit consisting of various pieces of magnetic blocks for a unilateral MRI device, which generates a homogeneous magnetic flux density at a remote region. The direction of the remanent flux density of the main outer magnetic blocks is parallel to the surface of the device; hence the direction of the magnetic flux density in the remote region is also parallel to the surface of the device. The magnitudes of the remanent flux density of the magnetic blocks are adjusted so as to minimize the variation of the magnetic flux density in the remote region. This magnetic circuit, with an outer dimension of 400 mm × 400 mm × 200 mm, produces a magnetic flux density in a 20 mm × 20 mm × 5 mm region of interest at a distance of 55 mm from the surface of the device with a magnitude of 64.5 mT (2.75 MHz in resonant frequency) and a uniformity of 275 ppm (755 Hz in band width). © 2008 Wiley Periodicals, Inc. Concepts Magn Reson Part B (Magn Reson Engineering) 33B: 201–208, 2008
A versatile high speed 250‐MHz pulse imager for biomedical applications
Authors: Epel Boris , Sundramoorthy Subramanian V. , Mailer Colin , Halpern Howard J. 
Published: July 2008

AbstractA versatile 250‐MHz pulse electron paramagnetic resonance (EPR) instrument for imaging of small animals is presented. Flexible design of the imager hardware and software makes it possible to use virtually any pulse EPR imaging modality. A fast pulse generation and data acquisition system based on general purpose PCI boards performs measurements with minimal additional delays. Careful design of receiver protection circuitry allowed us to achieve very high sensitivity of the instrument. In this article, we demonstrate the ability of the instrument to obtain three‐dimensional (3D) images using the electron spin echo (ESE) and single‐point imaging (SPI) methods. In a phantom that contains a 1 mM solution of narrow line (16 μT, peak‐to‐peak) paramagnetic spin probe, we achieved an acquisition time of 32 s per image with a fast 3D ESE imaging protocol. Using an 18‐min 3D phase relaxation (T2e) ESE imaging protocol in a homogeneous sample, a spatial resolution of 1.4 mm and a standard deviation of T2e of 8.5% were achieved. When applied to in vivo imaging this precision of T2e determination would be equivalent to 2 Torr resolution of oxygen partial pressure in animal tissues. © 2008 Wiley Periodicals, Inc. Concepts Magn Reson Part B (Magn Reson Engineering) 33B: 163–176, 2008