bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effects of doxycycline on articular cartilage GAG release and mechanical properties following impact
Authors: Blumberg Todd J. , Natoli Roman M. , Athanasiou Kyriacos A. 
Published: January 2008

AbstractThe effects of doxycycline were examined on articular cartilage glycosaminoglycan (GAG) release and biphasic mechanical properties following two levels of impact loading at 1 and 2 weeks post‐injury. Further, treatment for two continuous weeks was compared to treatment for only the 1st week of a 2‐week culture period. Following impact at two levels, articular cartilage explants were cultured for 1 or 2 weeks with 0, 50, or 100 µM doxycycline. Histology, GAG release to the media, and creep indentation biomechanical properties were examined. The “High” (2.8 J) impact level had gross surface damage, whereas “Low” (1.1 J) impact was indiscernible from non‐impacted controls. GAG staining decreased after High impact, but doxycycline did not visibly affect staining. High impact resulted in decreased aggregate moduli at both 1 and 2 weeks and increased permeability at 2 weeks, but tissue mechanical properties were not affected by doxycycline treatment. At 1 week, High impact resulted in more GAG release compared to non‐impacted controls. However, following High impact, 100 µM doxycycline reduced cumulative GAG release at 1 and 2 weeks by 30% and 38%, respectively, compared to no treatment. Interestingly, there was no difference in GAG release comparing 2 weeks continuous treatment with 1 week on, 1 week off. These results support the hypothesis that doxycycline can mitigate GAG release from articular cartilage following impact loads. However, doxycycline was unable to prevent the loss of tissue stiffness observed post‐impact, presumably due to initial matrix damage resulting solely from mechanical trauma. Biotechnol. Bioeng. 2008;100: 506–515. © 2008 Wiley Periodicals, Inc.
Fungal mycelia show lag time before re‐growth on endogenous carbon
Authors: Pollack Judith K. , Li Zheng Jian , Marten Mark R. 
Published: January 2008

AbstractNutrient starvation is a common occurrence for filamentous fungi. To better understand the effects of starvation, we used a parallel plate flow chamber to study individual fungal mycelia when subjected to a step change in glucose concentration. We report the presence of a finite “lag time” in starved mycelia during which they ceased to grow/extend while switching from growth on exogenous carbon to re‐growth on endogenous carbon. This lag time precedes other morphological or physiological changes such as change in growth rate (50–70% reduction), vacuolation (up to 16%), and decreased hyphal diameter (almost 50% reduction). Data suggests that during lag time, vacuolar degradation produces sufficient endogenous carbon to support survival and restart hyphal extension. Lag time is inversely related to the size of the mycelium at the time of starvation, which suggests a critical flow of endogenous carbon to the apical tip. We present a mathematical model consistent with our experimental observations that relate lag time, area, and flow of endogenous carbon. Biotechnol. Bioeng. 2008;100: 458–465. © 2008 Wiley Periodicals, Inc.
Charge‐directed targeting of antimicrobial protein‐nanoparticle conjugates
Authors: Satishkumar Rohan , Vertegel Alexey 
Published: January 2008

AbstractUse of antimicrobial enzymes covalently attached to nanoparticles is of great interest as an antibiotic‐free approach to treat microbial infections. Intrinsic properties of nanoparticles can also be used to add functionality to their conjugates with biomolecules. Here, we show in a model system that nanoparticle charge can be used to enhance delivery and increase bactericidal activity of an antimicrobial enzyme, lysozyme. Hen egg lysozyme was covalently attached to two types of polystyrene latex nanoparticles: positively charged, containing aliphatic amine surface groups, and negatively charged, containing sulfate and chloromethyl surface groups. In the case of bacterial lysis assay with a Gram‐positive bacteria Micrococcus lysodeikticus, activity of lysozyme conjugated to positively charged nanoparticles was approximately twice as large as that of free lysozyme, while lysozyme conjugated to negatively charged nanoparticles showed little detectable activity. At the same time, when assayed using a low‐molecular weight oligosaccharide substrate, lysozyme attached to both positively and negatively charged nanoparticles showed slightly lower activity than free enzyme. A possible explanation of these results is that lysozyme attached to negatively charged nanoparticles cannot be effectively targeted to the bacteria because of the electrostatic Coulombic repulsion from the negatively charged bacterial cell walls, whereas lysozyme conjugated to positively charged nanoparticles was targeted better than free enzyme due to stronger electrostatic attraction to bacteria. Zeta potential measurements confirmed the validity of this hypothesis. Thus, nanoparticle charge is an important factor that can be used to control targeting and activity of protein‐nanoparticle conjugates. Biotechnol. Bioeng. 2008;100: 403–412. © 2008 Wiley Periodicals, Inc.
Strong Dissimilarities Between the Gas‐Phase Acidities of Saturated and α,β‐Unsaturated Boranes and the Corresponding Alanes and Gallanes
Authors: Gámez José A. , Guillemin Jean‐Claude , Mó Otilia , Yáñez Manuel 
Published: January 2008

AbstractThe effect that unsaturation has on the intrinsic acidity of boranes, alanes, and gallanes, was analyzed by B3 LYP and CCSD(T)/6–311+G(3df,2p) calculations on methyl‐, ethyl‐, vinyl‐, and ethynylboranes, ‐alanes and ‐gallanes, and on the corresponding hydrides XH3. Quite unexpectedly, methylborane, which behaves as a carbon acid, is predicted to have an intrinsic acidity almost 200 kJ mol−1stronger than BH3, reflecting the large reinforcement of the CB bond, which upon deprotonation becomes a double bond through the donation of the lone pair created on the carbon atom into the empty p orbital of the boron. Also unexpectedly, and for the same reason, the saturated and α,β‐unsaturated boranes are much stronger acids than the corresponding hydrocarbons, in spite of being carbon acids as well. The Al derivatives also behave as carbon acids, but in this case the most favorable deprotonation process occurs at Cβ, leading to the formation of rather stable three‐membered rings, again through the donation of the Cβlone pair into the empty p orbital of Al. For Ga‐containing compounds the deprotonation of the GaH2group is the most favorable process. Therefore only Ga derivatives behave similarly to the analogues of Groups 14, 15, and 16 of the periodic table, and the saturated derivatives exhibit a weaker acidity than the unsaturated ones. Within Group 13, boranes are stronger acids than alanes and gallanes. For ethyl and vinyl derivatives, alanes are stronger acids than gallanes. We have shown, for the first time, that acidity enhancement for primary heterocompounds is not only dictated by the position of the heteroatom in the periodic table and the nature of the substituent, but also by the bonding rearrangements triggered by the deprotonation of the neutral acid.
The Isomers of Gadolinium Scandium Nitride Clusterfullerenes GdxSc3−xN@C80 (x=1, 2) and Their Influence on Cluster Structure
Authors: Yang Shangfeng , Popov Alexey , Kalbac Martin , Dunsch Lothar 
Published: January 2008

AbstractThe isomers of gadolinium scandium mixed‐metal nitride clusterfullerenes GdxSc3−xN@C80 [x=2 (1, 4); x=1 (2, 5)] have been synthesized by the “reactive gas atmosphere” method and isolated facilely by recycling HPLC. The yield of GdxSc3−xN@C80 (I, II) (x=1, 2) relative to the homogenous clusterfullerenes Sc3N@C80 [I (3), II (6)] was determined. According to the UV/Vis/NIR spectroscopic data, 1, 2, 4, and 5 are all stable fullerenes with large optical gaps. Fullerene 1 has greater similarity to Gd3N@C80 (I) and 2 seems to resemble Sc3N@C80 (I). The quite similar overall absorption features of 4 and 5 suggest pronounced similarity in electronic structure. Vibrational spectroscopic studies led to the assignment of the cage symmetries of GdxSc3−xN@C80 (I, II), that is, Ih for 1, 2 and D5h for 4, 5. The cluster–cage interactions in GdxSc3−xN@C80 (I, II) were analyzed by means of the low‐energy Raman lines. The splitting of the metal–nitrogen stretching vibrational mode in GdxSc3−xN@C80 (I, II) was studied in detail. Scalar‐relativistic DFT calculations were performed to reveal the geometry parameters and the magnetic state of the GdxSc3−xN@C80 (I, II) molecules.
ChemInform Abstract: A Neutron Diffraction Study of the d0 and d10 Lithium Garnets Li3Nd3W2O12 and Li5La3Sb2O12.
Authors: Cussen Edmund J. , Yip Thomas W. S. 
Published: January 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Vibrational Spectrum and Electronic Structure of the [B11H11]2‐ Dianion.
Authors: Kononova Elena G. , Leites Larissa A. , Bukalov Sergey S. , Pisareva Irina V. , Chizhevsky Igor T. , Kennedy John D. , Bould Jonathan 
Published: January 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Magnetic Structures of the M2TbF6 (M: Li, K, Rb) Fluorides: A Complex Behavior Resulting from Frustration.
Authors: Josse M. , El‐Ghozzi M. , Avignant D. , Andre G. , Bouree F. 
Published: January 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Photocatalytic Activity of a Novel Bi‐Based Oxychloride Catalyst Na0.5Bi1.5O2Cl.
Authors: Lin Xinping , Shan Zhichao , Li Kaiqiang , Wang Wendeng , Yang Jianhua , Huang Fuqiang 
Published: January 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Work Function of a Room‐Temperature, Stable Electride [Ca24Al28O64] 4+(e‐)4.
Authors: Toda Yoshitake , Yanagi Hiroshi , Ikenaga Eiji , Kim Jung Jin , Kobata Masaaki , Ueda Sigenori , Kamiya Toshio , Hirano Masahiro , Kobayashi Keisuke , Hosono Hideo 
Published: January 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: (NH4)2Te2WO8: A New Polar Oxide with Second‐Harmonic Generating, Ferroelectric, and Pyroelectric Properties.
Authors: Kim Jun‐Ho , Baek Jaewook , Halasyamani P. Shiv 
Published: January 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Hydrothermal Synthesis, Thermal, Structural, Spectroscopic and Magnetic Studies of the Mn5‐xCox(HPO4)2 (PO4)2(H2O)4 (x = 1.25, 2, 2.5 and 3) Finite Solid Solution.
Authors: Larrea Edurne S. , Mesa Jose L. , Pizarro Jose L. , Arriortua Maria I. , Rojo Teofilo 
Published: January 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: t‐Bu‐QuinoxP* Ligand: Applications in Asymmetric Pd‐Catalyzed Allylic Substitution and Ru‐Catalyzed Hydrogenation.
Authors: Imamoto Tsuneo , Nishimura Miwako , Koide Aya , Yoshida Kazuhiro 
Published: January 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: A Practical and Efficient Procedure for Reduction of Carboxylic Acids and Their Derivatives: Use of KBH4—MgCl2.
Authors: Qiu You‐Chun , Zhang Fu‐Li , Zhang Chun‐Nian 
Published: January 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Novel and Efficient Synthesis of 1‐Iodoalkynes.
Authors: Yan Jie , Li Jinghua , Cheng Dongping 
Published: January 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Reductive Methylation of Primary and Secondary Amines and Amino Acids by Aqueous Formaldehyde and Zinc.
Authors: da Silva Renato A. , Estevam Idalia H. S. , Bieber Lothar W. 
Published: January 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: An Efficient, Inexpensive, and Shelf‐Stable Diazotransfer Reagent: Imidazole‐1‐sulfonyl Azide Hydrochloride.
Authors: Goddard‐Borger Ethan D. , Stick Robert V. 
Published: January 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Solvent‐Free Knoevenagel Condensations over TiO2.
Authors: Hossaini‐Sarvari Mona , Sharghi Hashem , Etemad Samane 
Published: January 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Highly Recoverable Pyridinium‐Tagged Hoveyda—Grubbs Pre‐Catalyst for Olefin Metathesis. Design of the Boomerang Ligand Toward the Optimal Compromise Between Activity and Reusability.
Authors: Rix Diane , Caijo Frederic , Laurent Isabelle , Gulajski Lukasz , Grela Karol , Mauduit Marc 
Published: January 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Conformational Behaviors of Tetra‐O‐methylsulfinylcalix[4]arenes — An Approach to Control the Conformation of Thiacalix[4]arenes by Oxidizing Sulfur Bridges.
Authors: Katagiri Hiroshi , Hattori Tetsutaro , Morohashi Naoya , Iki Nobukiho , Miyano Sotaro 
Published: January 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Ir‐Catalyzed Allylic Amination/Ring‐Closing Metathesis: A New Route to Enantioselective Synthesis of Cyclic β‐Amino Alcohol Derivatives.
Authors: Lee Jun Hee , Shin Seunghoon , Kang Jahyo , Lee Sang‐gi 
Published: January 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Acyclic Stereocontrol in the Ireland—Claisen Rearrangement of α‐Branched Esters.
Authors: Qin Ying‐chuan , Stivala Craig E. , Zakarian Armen 
Published: January 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Intermolecular Hydroamination of Vinyl Arenes Using Tungstophosphoric Acid as a Simple and Efficient Catalyst.
Authors: Babu N. Seshu , Reddy K. Mohan , Prasad P. S. Sai , Suryanarayana I. , Lingaiah N. 
Published: January 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Tandem Reductive Perfluoroalkylation of Esters with Perfluoroalkyl Titanate‐Type Reagents.
Authors: Mikami Koichi , Murase Tatsushi , Itoh Yoshimitsu 
Published: January 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Organocatalytic Asymmetric Mannich Reactions with N‐Boc‐ and N‐Cbz‐Protected α‐Amido Sulfones (Boc: tert‐Butoxycarbonyl, Cbz: Benzyloxycarbonyl).
Authors: Marianacci Olindo , Micheletti Gabriele , Bernardi Luca , Fini Francesco , Fochi Mariafrancesca , Pettersen Daniel , Sgarzani Valentina , Ricci Alfredo 
Published: January 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Highly Efficient Direct Alkylation of Activated Methylene by Cycloalkanes.
Authors: Zhang Yuhua , Li Chao‐Jun 
Published: January 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Microwave‐Assisted Solvent‐Free Synthesis of Enol Carbamates.
Authors: Seijas Julio A. , Vazquez‐Tato M. Pilar , Crecente‐Campo Jose 
Published: January 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Inhibition of Homocoupling of Arylboronic Acids in Ligand‐Free Pd(II)‐Catalyzed Suzuki Reaction.
Authors: Tao Xiao‐Chun , Zhang Yue‐Ping , He Tian‐Xiong , Shen Dong 
Published: January 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Highly Efficient and Reusable Supported Pd Catalysts for Suzuki—Miyaura Reactions of Aryl Chlorides.
Authors: Schweizer Stephane , Becht Jean‐Michel , Le Drian Claude 
Published: January 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: An Efficient Synthesis of Unsymmetrical Diarylmethanes from the Dehydration of Arenes with Benzyl Alcohols Using InCl3×4H2O/Acetylacetone Catalyst System.
Authors: Sun Hong‐Bin , Li Biao , Chen Songjie , Li Jie , Hua Ruimao 
Published: January 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Prolinamides Derived from Aminophenols as Organocatalysts for Asymmetric Direct Aldol Reactions.
Authors: Sathapornvajana Sornpranart , Vilaivan Tirayut 
Published: January 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Interrupted Nazarov Reactions Using Dichlorocyclopropanes: A Novel Mode of Arene Trapping.
Authors: Grant Tina N. , West F. G. 
Published: January 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Asymmetric Intramolecular Alkylation of Chiral Aromatic Imines via Catalytic C—H Bond Activation.
Authors: Watzke Anja , Wilson Rebecca M. , O'Malley Steven J. , Bergman Robert G. , Ellman Jonathan A. 
Published: January 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.