bluuebunny/crossref_metadata_2025_split huggingface dataset:
trans‐2,5‐Disubstituted Pyrrolidines: Rapid Stereocontrolled Access from Sulfones.
Authors: Moloney Mark G. , Panchal Terry , Pike Richard 
Published: February 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
5‐endo Heck‐Type Cyclization of 2‐(Trifluoromethyl)allyl Ketone Oximes: Synthesis of 4‐Difluoromethylene‐Substituted 1‐Pyrrolines.
Authors: Ichikawa Junji , Nadano Ryo , Ito Naotaka 
Published: February 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
A Palladium‐Catalyzed Tandem Cyclization‐Cross‐Coupling Reaction Using Indolylborate as a Transfer Agent.
Authors: Ishikura Minoru , Takahashi Norinobu , Yamada Koji , Yanada Reiko 
Published: February 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Fully Automated Continuous Flow Synthesis of 4,5‐Disubstituted Oxazoles.
Authors: Baumann Marcus , Baxendale Ian R. , Ley Steven V. , Smith Christoper D. , Tranmer Geoffrey K. 
Published: February 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Diastereoselective Multicomponent Synthesis of Dihydropyridones with an Isocyanide Functionality.
Authors: Orru Romano V. A. , et al. et al. 
Published: February 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Mild and Convenient Synthesis of 1,2‐Dihydroquinolines from Anilines and Acetone Catalyzed by Ytterbium(III) Triflate in Ionic Liquids.
Authors: Li Yongshu , Wu Chunlei , Huang Jianliang , Su Weike 
Published: February 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Intramolecular Hetero‐Diels—Alder Reactions Catalyzed by BiCl3: Stereoselective Synthesis of Benzo‐Anellated Decahydrofuro[3,2‐h][1,6]naphthyridine Derivatives.
Authors: Sabitha Gowravaram , Maruthi Chittapragada , Reddy Erigala Venkata , Srinivas Chitti , Yadav Jhillu S. , Dutta Samit K. , Kunwar Ajit C. 
Published: February 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Facile Synthesis of Pyrazolo[3,4‐d]pyrimidines and Pyrimido[4,5‐d]pyrimidin‐4‐one Derivatives.
Authors: Katiyar Sanjay Babu , Kumar Arun , Chauhan Prem M. S. 
Published: February 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Synthesis of 1‐(Alkoxymethyl)‐5‐benzyl‐6‐methyluracil as Potential Nonnucleoside HIV‐1 RT Inhibitors.
Authors: Chen Yanli , Guo Ying , Yang Hua , Wang Xiaowei , Liu Junyi 
Published: February 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Intermolecular One‐Pot Cyclization of Formyl‐Pyrroles of Amino Acid Esters with Norephedrine: Stereoselective Routes to New Tricyclic Pyrrole—Pyrazine—Oxazole Fused Structures.
Authors: Demir Ayhan S. , Subasi N. Tuna , Sahin Ertan 
Published: February 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Efficient Synthesis of Dialkyl (2Z)‐2‐[(E)‐1‐Aryl‐2‐(3‐arylquinoxalin‐2‐yl)ethenyl]but‐2‐enedioates.
Authors: Yavari Issa , Mirzaei Anvar , Moradi Loghman 
Published: February 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Convenient Synthesis of Oxazolidinones and Oxazinones from Allyl and Homoallyl Amines under Mild Conditions.
Authors: Garcia‐Egido Eduardo , Fernandez Isabelle , Munoz Luis 
Published: February 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Enantioselective Diethylzinc Addition to the Exocyclic C=N Double Bond of Some 4‐Arylideneamino‐3‐mercapto‐6‐methyl‐4H‐1,2,4‐triazin‐5‐one Derivatives.
Authors: El‐Shehawy Ashraf A. 
Published: February 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Identification and Optimization of 5‐Amino‐7‐aryldihydro‐1,4‐diazepines as 5‐HT2A Ligands.
Authors: Swain Christopher J. , Teran Ana , Maroto Marta , Cabello Angeles 
Published: February 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
One‐Pot Synthesis of Lactams from Cycloalkanes and tert‐Butyl Nitrite by Using N‐Hydroxyphthalimide as Key Catalyst.
Authors: Hashimoto Masaharu , Sakaguchi Satoshi , Ishii Yasutaka 
Published: February 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Stereoselective Preparation of 1‐Siloxy‐1‐alkenylcopper Species by 1,2‐Csp2‐to‐O Silyl Migration of Acylsilanes.
Authors: Tsubouchi Akira , Onishi Kotaro , Takeda Takeshi 
Published: February 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Facile Synthesis of Bis‐α‐aminoalkylphosphinates.
Authors: Drag Marcin , Dlugosz Katarzyna , Oleksyszyn Jozef 
Published: February 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Revision of the Structures of Citrifolinin A, Citrifolinoside, Yopaaoside A, Yopaaoside B, and Morindacin, Iridoids from Morinda citrifolia L. and Morinda coreia Ham.
Authors: Schripsema Jan , Caprini Geisa P. , Dagnino Denise 
Published: February 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
New Cytotoxic Cembranolides: Isolation, Biogenetic Studies, and Synthesis of Analogues.
Authors: Nieto M. Isabel , Gonzalez Noemi , Rodriguez Jaime , Kerr Russell G. , Jimenez Carlos 
Published: February 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Sulfated Meroterpenoids from the Brazilian Sponge Callyspongia sp. Are Inhibitors of the Antileishmaniasis Target Adenosine Phosphoribosyl Transferase.
Authors: Gray Christopher A. , de Lira Simone P. , Silva Marcio , Pimenta Eli F. , Thiemann Otavio H. , Oliva Glaucius , Hajdu Eduardo , Andersen Raymond J. , Berlinck Roberto G. S. 
Published: February 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Stereoselective Synthesis of Androstane‐Based Steroidal Phosphine Oxides Possessing the 16α‐Diphenylphosphinyl Moiety.
Authors: Skoda‐Foeldes Rita , Kollar Laszlo 
Published: February 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Five New Steroidal Compounds from Ypsilandra thibetica.
Authors: Xie Bai‐Bo , Liu Hai‐Yang , Ni Wei , Chen Chang‐Xiang , Lue Yang , Wu Li , Zheng Qi‐Tai 
Published: February 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
A Palladium‐Catalyzed Synthesis of Isoalliin, the Main Cysteine Sulfoxide in Onions (Allium cepa).
Authors: Namyslo Jan C. , Stanitzek Claudia 
Published: February 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Practical and Efficient Synthesis of Orthogonally Protected α‐2,3‐Diaminopropionic Acid (2,3‐Dap), 2,4‐Diaminobutanoic Acid (2,4‐Dab), and Their N‐Methylated Derivatives.
Authors: Rao R. V. Ramana , Tantry Subramanyam J. , Babu Vommina V. Suresh 
Published: February 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Azumamides A‐E: Histone Deacetylase Inhibitory Cyclic Tetrapeptides from the Marine Sponge Mycale izuensis.
Authors: Nakao Yoichi , Yoshida Satoru , Matsunaga Shigeki , Shindoh Nobuaki , Terada Yoh , Nagai Koji , Yamashita Jun K. , Ganesan A. , van Soest Rob W. M. , Fusetani Nobuhiro 
Published: February 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Use of 2,2′‐Dibenzothiazolyl Disulfide‐Triphenylphosphine and Lawesson′s Reagent in the Cyclization of β‐Amino Acids.
Authors: Kanwar Seema , Sharma S. D. 
Published: February 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Structural Characterization of Microcystins by LC/MS/MS under Ion Trap Conditions.
Authors: Mayumi Tsuyoshi , Kato Hajime , Imanishi Susumu , Kawasaki Yoshito , Hasegawa Masateru , Harada Ken‐ichi 
Published: February 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Structure Reassignment and Synthesis of Jenamidines A1/A2, Synthesis of (+)‐NP25302, and Formal Synthesis of SB‐311009 Analogues.
Authors: Duvall Jeremy R. , Wu Fanghui , Snider Barry B. 
Published: February 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Microwave‐Assisted Synthesis of N‐Pyrazole Ureas and the p38α Inhibitor BIRB 796 for Study into Accelerated Cell Ageing.
Authors: Bagley Mark C. , Davis Terence , Dix Matthew C. , Widdowson Caroline S. , Kipling David 
Published: February 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Rapid Microwave‐Assisted Fluorination Yielding Novel 5′‐Deoxy‐5′‐fluorouridine Derivatives.
Authors: Le H. Phuoc , Mueller Christa E. 
Published: February 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Synthesis and Biological Evaluation of 2‐ and 7‐Substituted 9‐Deazaadenosine Analogues.
Authors: Liu Mao‐Chin , Luo Mei‐Zhen , Mozdziesz Diane E. , Sartorelli Alan C. 
Published: February 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Synthesis and anti‐HCMV Activity of Novel 2′,3′,4′‐Trimethyl Branched Carbocyclic Nucleosides.
Authors: Kim Aihong , Hong Joon Hee 
Published: February 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Synthesis and DNA Binding Properties of a New Benzo[f]imidazo[1,5‐b]‐isoquinoline‐butan‐1,2‐diol Derivative (V).
Authors: Aly Youssef L. , Pedersen Erik B. 
Published: February 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Stereoselective Total Synthesis of the Proposed Structure of 2‐Epibotcinolide.
Authors: Shiina Isamu , Takasuna Yu‐ji , Suzuki Ryo‐suke , Oshiumi Hiromi , Komiyama Yuri , Hitomi Seiichi , Fukui Hiroki 
Published: February 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
A Short and Efficient Synthesis of (R)‐(‐)‐Sporochnol A (I).
Authors: Alibes Ramon , Busque Felix , Bardaji Gisela G. , de March Pedro , Figueredo Marta , Font Josep 
Published: February 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Highly Convergent Three‐Component Benzyne Coupling: The Total Synthesis of ent‐Clavilactone B.
Authors: Larrosa Igor , Da Silva Marianne I. , Gomez Patricio M. , Hannen Peter , Ko Eunjung , Lenger Steven R. , Linke Simon R. , White Andrew J. P. , Wilton Donna , Barrett Anthony G. M. 
Published: February 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Antibiotics from GIiding Bacteria. Part 105. Isolation and Structure Elucidation of Cruentarens A and B — Novel Members of the Benzolactone Class of ATPase Inhibitors from the Myxobacterium Byssovorax cruenta.
Authors: Jundt Larissa , Steinmetz Heinrich , Luger Peter , Weber Manuela , Kunze Brigitte , Reichenbach Hans , Hoefle Gerhard 
Published: February 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
The Total Synthesis of (+)‐Tedanolide.
Authors: Ehrlich Gunnar , Hassfeld Jorma , Eggert Ulrike , Kalesse Markus 
Published: February 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Synthesis of the Spiroacetal‐Containing anti‐Helicobacter pylori Agents CJ‐12,954 and CJ‐13,014.
Authors: Brimble Margaret A. , Bryant Christina J. 
Published: February 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
The Importance of Local Chemical Structure for Chemical Metabolism by Human Uridine 5′‐Diphosphate—Glucuronosyltransferase.
Authors: Sorich Michael J. , McKinnon Ross A. , Miners John O. , Smith Paul A. 
Published: February 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Ligand‐Based Approach to in Silico Pharmacology: Nuclear Receptor Profiling.
Authors: Mestres Jordi , Martin‐Couce Lidia , Gregori‐Puigjane Elisabet , Cases Montserrat , Boyer Scott 
Published: February 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Spiropyran‐Based Liquid Crystals: The Formation of Columnar Phases via Acid‐Induced Spiro‐merocyanine Isomerization.
Authors: Tan Boon‐Hooi , Yoshio Masafumi , Ichikawa Takahiro , Mukai Tomohiro , Ohno Hiroyuki , Kato Takashi 
Published: February 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Recent Advances in Tailoring the Aggregation of Heavier Alkaline Earth Metal Halides, Alkoxides and Aryloxides from Non‐Aqueous Solvents
Authors: Fromm Katharina M. 
Published: February 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Metallodendrimers: Fractals and Photonics
Authors: Cho Tae Joon , Moorefield Charles N. , Wang Pingshan , Newkome George R. 
Published: February 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
5,6‐Dihydroindolizine Core Formation under Rhodium‐Catalyzed Hydroformylation of N‐Allylpyrroles
Authors: Settambolo Roberta , Guazzelli Giuditta , Lazzaroni Raffaello 
Published: February 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Palladium‐Catalyzed Cross‐Coupling Reactions on Pyridazine Moieties
Authors: Nara Susheel , Martinez Jean , Wermuth Camille‐Georges , Parrot Isabelle 
Published: February 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Catalytic Oxidative Processes in Steroid Chemistry. Allylic Oxidation, β‐Selective Epoxidation, Alcohol Oxidation and Remote Functionalization Reactions
Authors: Salvador Jorge A. R. , Silvestre Samuel M. , Moreira Vania M. 
Published: February 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Catalytic Applications of Transition‐Metal Complexes Bearing Diphosphinidenecyclobutenes (DPCB)
Authors: Ozawa Fumiyuki , Yoshifuji Masaaki 
Published: February 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Conceptual, Qualitative, and Quantitative Theories of 1,3‐Dipolar and Diels—Alder Cycloadditions Used in Synthesis
Authors: Ess Daniel H. , Jones Gavin O. , Houk K. N. 
Published: February 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
A comparison of low‐dose cytarabine and hydroxyurea with or without all‐trans retinoic acid for acute myeloid leukemia and high‐risk myelodysplastic syndrome in patients not considered fit for intensive treatment
Authors: Burnett Alan K. , Milligan Donald , Prentice Archie G. , Goldstone Anthony H. , McMullin Mary F. , Hills Robert K. , Wheatley Keith 
Published: February 2007

AbstractBACKGROUNDThe survival of older patients with acute myeloid leukemia has not improved. Few clinical trials have been available for older patients who are not considered fit for an intensive chemotherapy approach.METHODSBetween December 1998 and November 2003, as part of National Cancer Research Institute Acute Myeloid Leukemia 14 Trial, 217 patients, who were deemed unfit for intensive chemotherapy were randomized to receive low‐dose cytarabine (Ara‐C) (20 mg twice daily for 10 days) or hydroxyurea with or without all‐trans retinoic acid (ATRA).RESULTSLow‐dose ara‐C produced a better remission rate (18% vs 1%; odds ratio [OR], 0.15; 95% confidence interval [95% CI], 0.06–0.37; P = .00006) and better overall survival (OR, 0.60; 95% CI, 0.44–0.81; P = .0009), which was accounted for by the achievement of complete remission (CR) (duration of CR: 80 weeks vs 10 weeks for patients with no CR). Patients who had adverse cytogenetics did not benefit. ATRA had no effect. Toxicity scores or supportive care requirements did not differ between the treatment arms.CONCLUSIONSOlder, less fit patients have a poor outcome, and few trials have been conducted in this patient group. Low‐dose ara‐C treatment was superior to best supportive care and hydroxyurea because it had greater success in achieving CR, and it could represent standard care against which new treatments may be compared in this patient group. [See editorial on pages 000–000, this issue.] Cancer 2007 © 2007 American Cancer Society.
Treatment of chronic myeloid leukemia in the imatinib era
Authors: Aziz Zeba , Iqbal Javaid , Akram Mohammad , Saeed Sarah 
Published: February 2007

AbstractBACKGROUNDThere is paucity of data from developing countries on the efficacy and safety of imatinib mesylate in chronic myeloid leukemia (CML). The primary objective of this study was to document complete and partial cytogenetic responses to imatinib in all phases of CML. Secondary objectives included evaluations of complete hematologic response, safety, time to progression, and survival.METHODSTwo hundred seventy‐five patients in all phases of CML who received treatment with imatinib from January 2001 to December 2005 were included in the study. All patients had on bone marrow or BCR‐ABL positive in peripheral blood by polymerase chain reaction.RESULTSAfter a median follow‐up of 18 months, major cytogenetic responses (Ph <35%) in chronic phase (CP), accelerated phase (AP), and blastic phase (BP) were documented in 61%, 57%, and 28% of patients, respectively. A complete cytogenetic response was observed in 39.4%, 35.7%, and 14.3% of patients in CP, AP, and BP, respectively; and a complete hematologic response was observed in 90%, 86%, and 30%, respectively. The median time to progression at 18 months was 91% in CP and 68% in AP. The overall survivals in CP, AP, and BP at 18 months was 92%, 74%, and 38%, respectively.CONCLUSIONSImpressive hematologic, cytogenetic, and molecular responses to imatinib were observed, similar to the responses reported in patients from Western countries. Patients had good compliance, toxicity was limited, and overall quality of life was improved markedly. The results indicated that the biology of CML is not different in patients from developing countries. Cancer 2007 © 2007 American Cancer Society.