bluuebunny/crossref_metadata_2025_split huggingface dataset:
Partnering Early to Provide for Infants At Risk of Cerebral Palsy (PĒPI ARC): protocol for a feasibility study of a regional hub for early detection of cerebral palsy in Aotearoa New Zealand
Authors: Allermo Fletcher Angelica , Kilgour Gaela , Sandle Meghan , Kidd Sally , Sheppard Alison , Swallow Stephanie , Stott Ngaire Susan , Battin Malcolm , Korent Wyllis , Williams Sian A. 
Published: April 2024

IntroductionCerebral palsy (CP) can now be diagnosed in infants with identified CP risk factors as early as three months of age; however, many barriers prevent equitable access to early detection pathways. The “Partnering Early to Provide for Infants At Risk of Cerebral Palsy” feasibility study (PĒPI ARC) seeks to trial a new approach to decrease inequitable health service in Aotearoa New Zealand for high-risk infants and their families. PĒPI ARC incorporates face-to-face clinics, an in-person and virtual Hub, and the use of telehealth to enable flexible access to CP assessments and support for health professionals in early CP detection.Methods and analysisA non-randomised feasibility study was conducted from a tertiary Neonatal Intensive Care Unit (NICU) in Wellington and included seven regional referral centres, servicing nearly 30% of the total population in New Zealand (NZ). The families of infants with a high risk of neurodevelopmental impairment and health professionals interacting with the Hub were invited to participate. Mixed methods were used to evaluate the (i) equitable implementation of an early detection pathway, (ii) acceptability, (iii) demand among families and health professionals, (iv) efficacy in relation to reducing the age of receipt of CP diagnosis, and (v) the experiences around communication and information sharing.Ethics and disseminationThe NZ Health and Disability Ethics Committee approved this study (HDEC: 2022 FULL 13434). The findings will be disseminated in peer-reviewed journals, in conference presentations, and via professional networks.Clinical trial registrationAustralian New Zealand Clinical Trials Registry: ACTRN12623000600640.
Low-dose and standard-dose whole-body [18F]FDG-PET/CT imaging: implications for healthy controls and lung cancer patients
Authors: Ferrara Daria , Shiyam Sundar Lalith Kumar , Chalampalakis Zacharias , Geist Barbara Katharina , Gompelmann Daniela , Gutschmayer Sebastian , Hacker Marcus , Kertész Hunor , Kluge Kilian , Idzko Marco , Langsteger Werner , Yu Josef , Rausch Ivo , Beyer Thomas 
Published: April 2024

Aim: High-sensitivity hybrid positron emission tomography (PET) imaging using advanced whole-body (WB) or total-body PET/computed tomography (CT) systems permits reducing injected tracer activity while preserving diagnostic quality. Such approaches are promising for healthy control studies or exploring inter-organ communication in systemic diseases. This study assessed test/retest variations in the fluoro-2-deoxy-D-glucose (FDG) uptake in key organs from low-dose (LD) and standard-dose (STD) [18F]FDG-PET/CT imaging protocols in healthy controls and lung cancer patients.Methods: A total of 19 healthy controls (19–62 years, 46–104 kg, 10 M/9 F) and 7 lung cancer patients (47–77 years, 50–88 kg, 4 M/3 F) underwent [18F]FDG-PET/CT imaging. All subjects were first injected (“test,” LD) with 28 ± 2 MBq FDG and underwent a dynamic (0–67 min post-injection) WB imaging protocol with LD-CT. Then, 90 min post-LD injection, the subjects were repositioned and injected with 275 ± 16 MBq FDG (“retest,” STD). Second LD-CT and STD-CT scans were acquired for healthy controls and patients, respectively. Static images (55–67 min post-injection) were considered for subsequent analysis. The CT images were used to automatically segment the target volumes of interest. Standardized uptake values normalized to the body weight (SUVBW) were extracted for each volume of interest. The mean SUVBW were compared for both LD/STD conditions with paired t-tests. In patients, FDG-avid lesions were manually delineated on LD and STD static images. Effective dose levels were estimated from both the CT and PET acquisitions.Results: Organ-based mean SUVBW were similar between the LD and STD (mean %difference ≤5%) in both healthy controls and cancer patients, except in the heart. Intra-control test/retest variability was significant in the brain, heart, and skeletal muscle (p &lt; 0.05). While 17 lesions were delineated on the STD images of the patients, only 10/17 lesions were identified on the LD images due to increased image noise. Lesion-based mean SUVBW were similar between LD and STD acquisitions (p = 0.49, %difference = 10%). In patients, the effective doses were (1.9 ± 0.2) mSv (LD-CT), (16.6 ± 5.4) mSv (STD-CT), (0.5 ± 0.1) mSv (LD-PET), and (4.6 ± 0.3) mSv (STD-PET).Conclusion: LD and STD [18F]FDG injections in healthy controls and lung cancer patients yielded comparable mean SUVBW, except in the heart. Dose levels may be reduced for [18F]FDG-PET imaging without a loss in mean SUVBW accuracy, promoting LD-PET/CT protocols for studying multi-organ metabolic patterns. In oncology patients, this approach may be hindered by a lower diagnostic quality in the presence of significant noise.
Wearable device for continuous sweat lactate monitoring in sports: a narrative review
Authors: Yang Geonwoo , Hong Junggi , Park Seung-Bo 
Published: April 2024

In sports science, the use of wearable technology has facilitated the development of new approaches for tracking and assessing athletes’ performance. This narrative review rigorously explores the evolution and contemporary state of wearable devices specifically engineered for continuously monitoring lactate levels in sweat, an essential biomarker for appraising endurance performance. Lactate threshold tests have traditionally been integral in tailoring training intensity for athletes, but these tests have relied on invasive blood tests that are impractical outside a laboratory setting. The transition to noninvasive, real-time monitoring through wearable technology introduces an innovative approach, facilitating continuous assessment without the constraints inherent in traditional methodologies. We selected 34 products from a pool of 246 articles found through a meticulous search of articles published up to January 2024 in renowned databases: PubMed, Web of Science, and ScienceDirect. We used keywords such as “sweat lactate monitoring,” “continuous lactate monitoring,” and “wearable devices.” The findings underscore the capabilities of noninvasive sweat lactate monitoring technologies to conduct long-term assessments over a broad range of 0–100 mM, providing a safer alternative with minimal infection risks. By enabling real-time evaluations of the lactate threshold (LT) and maximal lactate steady state (MLSS), these technologies offer athletes various device options tailored to their specific sports and preferences. This review explores the mechanisms of currently available lactate monitoring technologies, focusing on electrochemical sensors that have undergone extensive research and show promise for commercialization. These sensors employ amperometric reactions to quantify lactate levels and detect changes resulting from enzymatic activities. In contrast, colorimetric sensors offer a more straightforward and user-friendly approach by displaying lactate concentrations through color alterations. Despite significant advancements, the relationship between sweat lactate and blood lactate levels remains intricate owing to various factors such as environmental conditions and the lag between exercise initiation and sweating. Furthermore, there is a marked gap in research on sweat lactate compared to blood lactate across various sports disciplines. This review highlights the need for further research to address these shortcomings and substantiate the performance of lactate sweat monitoring technologies in a broader spectrum of sports environments. The tremendous potential of these technologies to supplant invasive blood lactate tests and pioneer new avenues for athlete management and performance optimization in real-world settings heralds a promising future for integrating sports science and wearable technology.
Physical activity on prescription for children with obesity: a focus group study exploring experiences in paediatric healthcare
Authors: Boman Charlotte , Bernhardsson Susanne , Lundqvist Stefan , Melin Karin , Lauruschkus Katarina 
Published: April 2024

BackgroundInsufficient physical activity is a growing public health concern and is closely linked to obesity in both adults and children. Swedish physical activity on prescription (PAP) is effective in increasing physical activity levels in adults, but knowledge about how PAP is used in paediatric healthcare is lacking. Therefore, this study aimed to explore experiences of working with PAP for children with obesity amongst paediatric staff and managers.MethodsSeven focus group discussions with 26 participants from paediatric outpatient clinics in western Sweden were conducted. Data were analysed both inductively and deductively, framed by the Normalization Process Theory's four core constructs: coherence, cognitive participation, collective action, and reflexive monitoring.ResultsThe PAP work for children with obesity was experienced to be about helping children to become physically active, and less about losing weight. Identified barriers for using PAP were the non-uniform nature of the work and a perceived lack of guidelines. Collaboration with physiotherapists and physical activity organisers outside the organisation was identified as an important facilitator. An important contextual factor for implementing PAP is the collaboration between paediatric clinics and physical activity organisers. In the transition between these stakeholders, maintaining a family-centred approach when working with PAP was experienced as challenging.ConclusionsPAP is a well-known intervention that is inconsistently used for children with obesity. The intervention should include a family-centred approach for this patient group. It also needs to align better with existing collaborations with other healthcare units as well as with new forms of collaboration with physical activity organisers in the community.
Assessing the usability of aromatic mouthwashes in alleviating physiological stress responses
Authors: Dilrukshi E. A. Chayani , Ogino Tatsuki , Ishikawa Mami , Kuroda Hiroki , Nomura Shusaku 
Published: April 2024

BackgroundMouthwashes play a pivotal role in oral care, and their efficacy has been explored extensively across various dimensions. As a contribution to the development of novel oral care products, this study aims to investigate the psychophysiological effects of aromatic mouthwashes during the resilience period from a short-term cognitive stressor utilizing biological signals and subjective evaluations.MethodsA within-participant experimental design with 22 healthy females was conducted with four mouthwashes; peppermint (Mint), peppermint + bergamot (MB), peppermint + sweet orange (MO), and peppermint + lavender (ML), and water as the control (Ctl), after a 20-min calculation task. Subjective evaluations and physiological responses including skin conductance level and electrocardiogram were recorded throughout the experiment.ResultsCitrus mouthwashes (MO and MB) showed a greater decrease in heart rate and a significant increase in the high-frequency component of heart rate variability. The participants indicated a significant effect in terms of “flavor preference” and “refreshing sensation” for mouthwash use compared to the Ctl.ConclusionThe results suggest that rinsing with citrus-flavored mouthwashes has a positive impact in alleviating the physiological stress response (in terms of cardiac activity). These findings may have implications for the development of innovative, novel oral care products that promote stress reduction and improve oral health.
Essential oils mix effect on chicks ileal and caecal microbiota modulation: a metagenomics sequencing approach
Authors: Girard Claire , Chabrillat Thibaut , Kerros Sylvain , Fravalo Philippe , Thibodeau Alexandre 
Published: April 2024

IntroductionMicrobiota plays a pivotal role in promoting the health and wellbeing of poultry. Essential oils (EOs) serve as an alternative solution for modulating poultry microbiota. This study aimed to investigate, using amplicon sequencing, the effect of a complex and well-defined combination of EOs feed supplement on both ileal and caecal broiler microbiota, within the context of Salmonella and Campylobacter intestinal colonization.Material and methodsFor this experiment, 150-day-old Ross chicks were randomly allocated to two groups: T+ (feed supplementation with EO mix 500 g/t) and T– (non-supplemented). At day 7, 30 birds from each group were orally inoculated with 106 CFU/bird of a Salmonella enteritidis and transferred to the second room, forming the following groups: TS+ (30 challenged birds receiving infeed EO mix at 500g/t) and TS– (30 challenged birds receiving a non-supplemented control feed). At day 14, the remaining birds in the first room were orally inoculated with 103 CFU/bird of two strains of Campylobacter jejuni, resulting in the formation of groups T+C+ and T–C+. Birds were sacrificed at day 7, D10, D14, D17, and D21. Ileal and caecal microbiota samples were analyzed using Illumina MiSeq sequencing. At D7 and D14, ileal alpha diversity was higher for treated birds (p &lt;0.05).Results and discussionNo significant differences between groups were observed in caecal alpha diversity (p&gt;0.05). The ileal beta diversity exhibited differences between groups at D7 (p &lt; 0.008), D10 (p = 0.029), D14 (p= 0.001) and D17 (p= 0.018), but not at D21 (p = 0.54). For all time points, the analysis indicated that 6 biomarkers were negatively impacted, while 10 biomarkers were positively impacted. Sellimonas and Weissella returned the lowest (negative) and highest (positive) coefficient, respectively. At each time point, treatments influenced caecal microbiota beta diversity (p &lt; 0.001); 31 genera were associated with T+: 10 Ruminoccocaceae genera were alternatively more abundant and less abundant from D7, 7 Lachnospiraceae genera were alternatively more and less abundant from D10, 6 Oscillospiraceae genera were variable depending on the date and 4 Enterobacteriaceae differed from D7. During all the experiment, Campylobacter decreased in treated birds (p &lt; 0.05). This study showed that EO mix modulates ileal and caecal microbiota composition both before and during challenge conditions, increasing alpha diversity, especially in ileum during the early stages of chick life.
AUDIT TATA KELOLA TEKNOLOGI INFORMASI PADA LAYANAN AKADEMIK FAKULTAS SAINS DAN TEKNOLOGI MENGGUNAKAN COBIT 2019
Authors: Suryani Suryani , Dwinnie Zairy Cindy , Dwynne Zaira Cindya , Pramana Jeki Harya , Megawati Megawati 
Published: April 2024

Perkembangan teknologi informasi mengharuskan perguruan tinggi untuk memperbarui dan meningkatkan infrastruktur teknologi informasi guna menghadapi persaingan dan memanfaatkan kemajuan zaman. Pelayanan menjadi aspek utama yang dapat memudahkan urusan publik dilingkungan perguruan tinggi. Penggunaan Framework COBIT 2019 dianggap sebagai panduan yang efektif untuk menerapkan Teknologi Informasi dalam mengelola Sistem Informasi Akademik di Fakultas Sains dan Teknologi Universitas Islam Negeri Sultan Syarif Kasim Riau. Framework ini memberikan kontribusi berharga dalam mendukung manajemen Teknologi Informasi secara menyeluruh. Penelitian ini memiliki tujuan khusus, yaitu menerapkan Framework COBIT 2019 untuk merancang tata kelola teknologi informasi yang efektif dalam pengelolaan bisnis dan teknologi. Harapannya, penelitian ini akan memberikan informasi yang relevan terkait penerapan tata kelola tersebut.
Kata kunci – Audit, COBIT 2019, Sistem Informasi Akademik
Concordancia entre la calorimetría indirecta y las ecuaciones predictivas para estimar gasto energético en reposo
Authors: Londoño-Londoño Lina Maria , Montoya-Bernal Ángela Patricia , Arango Fernando , Escobar-Serna José Fernando , Florián Pérez Maria Cristina , Trejos-Gallego Diana 
Published: April 2024

Introducción: la determinación del gasto energético es fundamental en los pacientes críticos debido a que la subalimentación o sobrealimentación aumenta su morbimortalidad.
Objetivo: determinar la exactitud y concordancia de la medición del gasto energético en reposo (GER) por calorimetría indirecta (CI) y tres fórmulas predictivas (Harris-Benedict, Regla del pulgar y Penn State) en pacientes ventilados de una UCI de Manizales, Colombia.
Métodos: se incluyeron 31 pacientes hospitalizados en el S.E.S. Hospital Universitario de Caldas, con ventilación mecánica ≥48 horas. El GER se calculó para todas las variaciones de peso corporal. Como una medida de precisión de las ecuaciones, se calculó la distribución de pacientes con GER por debajo del 80 % del medido por CI (subestimación), entre 80 % y 110 % (adecuado) y >110 % (sobreestimación), y a partir de análisis con Bland- Altman se evaluó la concordancia.
Resultados: el GER promedio por CI fue de 1441,1 (IC del 95 % 1205,7-1616,5) kcal/kg para mujeres y 1624,5 (IC del 95 % 1414,7–1834,2) para hombres. El análisis de exactitud mostró que la ecuación Penn State calculada con el peso actual tuvo una concordancia del 44,4 % y fue la que más subestimó con peso ideal y ajustado (51,9 %), la regla del pulgar calculada con el peso actual fue la que más sobreestimó (64,6 %) y el análisis con gráficos Bland-Altman mostró sesgos positivos y negativos.
Conclusiones: se encontró una mala concordancia entre las diferentes ecuaciones predictivas y los valores de GER por CI en pacientes críticamente enfermos de una UCI.
Pengembangan Kapasitas Usaha Petani Tanaman Hias Ramah Lingkungan di Kawasan Desa Wisata Taman Sari Kabupaten Bogor
Authors: Maharani MDD , Setyawati Ekaterina , Santoso Paulus Basuki Kuwat 
Published: April 2024

Selain memiliki daya tarik tertentu, tanaman hias memiliki nilai ekonomis yang dapat dijadikan sebagai komoditas perdagangan dan bisnis. Petani melakukan budidaya tanaman hias belum semuanya menggunakan teknik budidaya yang berkelanjutan. Seperti penanganganan hama pengganggu tanaman hias, petani belum semuanya menerapkan teknik penenggulangan hama pengganggu tanaman yang berkelanjutan. Pengabdian masayarakat ini mempunyai tujuan untuk memberikan pengetahuan kepada petani dalam menangani organisme pengganggu tanaman secara berkelanjutan. Tim pengabdi memberikan alternatif penanganan hama dengan memanfaatkan suatu alat yang dapat menangkap hama jantan pengganggiu tanaman. Alat penangkap dilengkapi dengan atraktan yang memanfaatkan minyak pala yang aromanya seperti cairan yang dikeluarkan hama betina saat birahi. Alat bekerja dengan baik terlebih pada sore hari banyak hama jantan berkumpul dan tertangkap oleh atraktan. Konsep alat penanggap ini adalah menghambat perkawinan dan menurunkan populasi dan tidak turun secara drastis. Pengetahuan ini diberikan kepada petani dan memberikan peningkatan pengetahuan dan keterampilan petani tanaman hias dalam mengendalikan hama secara ramah lingkungan.
The Effect of Physical Activity on Blood Pressure in the Community of Tumbang Tahai District, Palangka Raya, Indonesia
Authors: Anwar Muhammad Naufa , Hartoyo Riccardo , Sandhikarana I Dewa Gede , Widhiyanto Hendrykus Theo Damar , Praja Rian Ka 
Published: April 2024

Background: Cardiovascular diseases, including hypertension, pose significant health challenges globally. Physical activity has long been recognized as a modifiable factor that can influence various aspects of cardiovascular health, including blood pressure. However, the relationship between physical activity and blood pressure is complex and can be influenced by various factors such as cultural and regional differences.
Aims: The primary objective of this research was to examine the association between physical activity and blood pressure using a quasi-experimental design.
Methods: This study utilized a quasi-experimental design with a one-group pre-test post-test approach. The sample was selected using a total sampling technique. The independent and dependent variables in this research were physical activity and blood pressure. Data collection instruments employed in this study consisted of observation sheets, an aneroid sphygmomanometer, and a stethoscope. Data analysis was performed using the Wilcoxon test.
Results: This study showed that there was an association between physical activity and blood pressure.
Conclusion: this research sheds light on the relationship between physical activity and blood pressure. The findings underscore the importance of considering cultural and regional factors in designing health interventions.

Received: 20 November 2023, Reviewed: 21 November 2023, Revised: 14 March 2024, Accepted: 03 April 2024.
ANALISA DISTRIBUSI CURAH HUJAN PADA DAS SEKANAK KOTA PALEMBANG
Authors: Yunanda Mega 
Published: April 2024

Sungai sebagai sumber air merupakan salah satu sumber daya alam yang mempunyai banyak fungsi bagi kehidupan manusia. Di Kota Palembang banyak terdapat sungai, salah satunya adalah Sungai Sekanak yang merupakan anak Sungai Musi yang terletak di dalam Kota Palembang. Sungai Sekanak ini juga merupakan bagian dari sistem drainase yang terdiri dari 19 sistem yang ada di wilayah Kota Palembang berdasarkan identifikasi (laporan akhir; skenario pengembangan kota,2000)
Sungai sekanak merupakan salah satu saluran yang mempunyai peranan penting di kota Palembang. Sungai yang bermuara ke Sungai Musi ini merupakan drainase alamiah yang berubah menjadi drainase buatan. Sungai Sekanak sebagai sungai utama di DAS Sekanak merupakan sungai perkuatan tebing atau turap berupa pasangan batu kali. Inlet ke Sungai Sekanak banyak pula yang sama atau bahkan lebih rendah dari muka air sungai. Kondisi ini akan sangat berpengaruh pada saat hujan atau pun saat pasang. Ditambah lagi debit air Sungai Musi masuk ke sungai Sekanak. Hal ini akan menyebabkan air dari daerah sekitar sungai akan sulit mengalir ke dalam sungai dan akan menimbulkan genangan. Faktor lain yang cukup berpengaruh yaitu tingkat penyerapan air oleh tanah dan rawa-rawa di wilayah DAS Sekanak yang cukup rendah.