bluuebunny/crossref_metadata_2025_split huggingface dataset:
Patient-Reported Outcomes as a Recruitment Strategy for Clinical Trial Enrollment
Authors: Verdini Nicholas P. , Bryl Karolina L. , Baser Raymond E. , Lapen Kaitlyn , Mao Jun J. , Gillespie Erin F. 
Published: April 2024

ImportanceClinical trials are critical for progress in oncology; however, only 5% of the adult cancer population participates. Harnessing data that are routinely collected (ie, electronic patient-reported outcomes [ePROs]) may serve as a method to promote trial enrollment.ObjectiveTo evaluate if an ePRO-prompted recruitment strategy is associated with increased clinical trial enrollment.Design, Setting, and ParticipantsA randomized substudy was conducted from September 2022 to March 2023 at a multisite tertiary cancer center as part of an ongoing clinical trial that was testing a symptom-intervention for cancer-related fatigue. Patients with breast cancer who were undergoing radiotherapy who completed at least 1 ePRO questionnaire during the study period were included. Physician-level cluster randomization assigned fatigue-eligible patients to either receive a portal message invitation to a symptom-intervention trial or standard of care (SOC; physician-based referral).ExposureePRO questionnaires distributed in routine practice were queried weekly and screened for moderate or greater fatigue, the principle inclusion criterion for the primary trial. To assess the association of the portal message source with response and enrollment, every other patient received a message from the primary radiation oncology team or the referral service.Main Outcomes and MeasuresClinical trial response/referral and enrollment.ResultsA total of 1041 patients completed ePRO questionnaires, of whom 394 (38%; 53 Asian [13.6%], 43 Black [11.0%], 29 Hispanic [7.4%], and 262 White individuals [66.5%]; median [IQR] age, 55 [47-65] years) endorsed moderate or greater fatigue while receiving treatment. A total of 210 patients (53.3%) were assigned to receive a portal message and 184 (46.7%) patients, SOC. In the portal message group, 73 patients (35%) responded and 41 (20%) enrolled compared with 1 patient (0.5%) referred and 0 enrolled in the SOC group (P &amp;lt; .001). The response rate to portal messages favored the referral service vs the primary radiation oncology service (44% vs 26%; P = .01), but there was no significant difference in enrollments.Conclusions and RelevanceThe study results suggest that use of routine care ePROs was associated with greater enrollment in a symptom-intervention trial compared with physician-based referral. Messaging directly from the referral service may support enrollment and help reduce oncology physician-level barriers to trial enrollment for studies testing symptom interventions.
From Electrolyte and Electrode Materials to Large‐Area Protonic Ceramic Fuel Cells: A Review
Authors: Guo Shihang , Jiang Lulu , Li Yifeng , Zhong Peng , Ismail Sara Adeeba , Norby Truls , Han Donglin 
Published: April 2024

AbstractFuel cells can efficiently convert the chemical energy in fuels like hydrogen and methane into electricity and are an important component for the forthcoming hydrogen society. Compared with conventional solid oxide fuel cells (SOFCs) and proton exchange membrane fuel cells (PEMFCs), protonic ceramic fuel cells (PCFCs) using proton conducting solid oxides as the electrolyte operate at intermediate temperature (400–700 °C), enabling the reduction in cost by using inexpensive catalysts and structural materials. In the last couple of decades, the development of electrolyte and electrode materials for PCFCs has seen significant advances, including fabrication of large‐size cells, promoting PCFCs to step out of the lab toward real applications. This review provides a historic overview of the development of proton conducting oxides, summarizes recent progress on the development of electrolyte and electrode materials and large‐size cells, and discusses present problems and challenges ahead.
Fabrication of Flexible and Conductive Microneedle Array Electrodes from Silk Fibroin by Mesoscopic Engineering
Authors: Wang Xiao , Qiu Wu , Lu Changsheng , Jiang Zerong , Hou Chen , Li Yanru , Wang Yan , Du Haiman , Zhou Jin , Liu Xiang Yang 
Published: April 2024

AbstractConventional electrodes are of significant challenges in acquiring bioelectric signals concerning a high signal‐to‐noise ratio (SNR), long‐term and comfortable wear, low motional noise, etc. To resolve these issues, silk fibroin (SF) materials are adopted to create flexible microneedle array electrodes (FMNA‐electrode) based on meso‐engineering. The research approaches involve constructing flexible conductive electrodes from non‐conductive and bristle‐regenerated SF. By controlling the molecular interchain nucleation in the refolding process of unfolded regenerated SF molecules, this goal can be achieved. In this process, silver nanowires (Ag NWs) are adopted as meso‐dopants to reconstruct the meso‐electronic structure of SF films at the surface, while polyurethane (PU) is selected as molecular templates to facilitate the molecular nucleation in the refolding of SF molecules. This leads to the occurrence of SF‐PU meso‐hybridization, giving rise to more flexible meso‐hybridized SF. The SF‐PU FMNA‐electrode demonstrates biocompatibility, comfort wearing, long‐term monitoring capability, low motional noise, and a high SNR in the application of collecting ECG, EMG, and EOG signals. The outperformance of SF‐PU FMNA‐electrode is superior to both conventional wet and commercially available dry electrodes, paving the way for the next generation of flexible, skin‐friendly, durable, and high‐performance health monitoring devices and brain‐machine interfaces.
Catalytic Oxidation of BTX (Benzene, Toluene, and Xylene) Using Metal Oxide Perovskites
Authors: Yuan Jianhua , Li Guixiang , Liu Xiao , Yang Yun , Yu Fei , Cao Jianglin , Fei Zhaofu , Ma Jie , Nazeeruddin Mohammad K. , Dyson Paul J. 
Published: April 2024

AbstractThe high toxicity, volatility, and dispersion of the light aromatics, benzene, toluene, and xylene (BTX) pose a serious threat to the environment and human health. Compared to incineration, catalytic oxidation technologies for BTX removal offer benefits such as low energy consumption, high efficiency, and low pollution. ABO3–type perovskite catalysts (ABO3–PCs) are particularly promising materials for the catalytic oxidation of BTX due to their high activity and thermal stability, as well as their adjustable elemental composition and flexible structure allowing their properties to be improved. Nonetheless, the full potential of ABO3–PCs for the oxidation of BTX has yet to be reached. This review systematically and critically analyses progress in the catalytic oxidation of BTX by ABO3–PCs. Catalytic performance is assessed for each category of perovskite, including non–doped, doped (A–, B–, or A/B–site doped), and loading type (noble metal, metal oxide, and matrix composite), with structure–activity relationships are established. A kinetic model and proposed mechanism for the catalytic oxidation of BTX are also presented. Finally, the challenges and opportunities of ABO3–PCs applied to BTX oxidation and other reactions are highlighted.
Solution Processed Hybrid Lead Perovskite Films for White Light Emission and Lasing Applications
Authors: Chowdhury Subhadip , Mukhopadhyay Mrinmay K , Sanyal Milan K , Bhunia Satyaban , Satpati Biswarup , Giri Rajendra P , Bharatiya B , Shen Chen , Murphy Bridget M 
Published: April 2024

Abstract2D organic–inorganic hybrid lead halide perovskite films are fascinating optoelectronic materials for white‐light emission and lasing applications. Here, it is demonstrated that nano‐meter‐thick films of perovskites can be formed at room temperature using Langmuir–Schaefer (LS) deposition technique. In situ X‐ray measurements reveal a self‐assembly process of the 2D perovskite formation at the air–water interface. This formation process requires the presence of stearic acid monolayer on the water subphase having a solution of lead‐perovskite in dimethylformamide. Microscopy and X‐ray measurements of these nanofilms transferred onto substrates show crystalline phase formation that deviates from the known orthorhombic structure of the bulk crystals. The nanofilms exhibit novel broad optical emission with sharp band‐edge transition in temperature‐dependent photoluminescence studies. Also, their band‐edge emission is distinctly blue‐shifted compared to that of thicker 2D perovskite flakes prepared by the slow‐cooling chemical synthesis process. 2D flakes exhibit lasing that cannot be obtained in the LS nanofilms as their thicknesses are lower than the lasing wavelength prohibiting wave‐guide formation. The results show that the 2D single‐crystalline nature of the LS films and flakes are suitable materials to develop broad‐band white light emission across the entire visible range and to obtain lasing without external cavities, respectively.
High‐Resolution 3D Printing of Dual‐Curing Thiol‐Ene/Epoxy System for Fabrication of Microfluidic Devices for Bioassays
Authors: Böcherer David , Li Yuanyuan , Rein Christof , Franco Corredor Santiago , Hou Peilong , Helmer Dorothea 
Published: April 2024

AbstractThe customized processing of polymer materials in the microscale by high‐resolution 3D printing provides an easy access to advanced applications in the fields of optics, microfluidics, tissue engineering, and life science. However, the 3D printing of enclosed structures in the scale of tens of microns such as closed microfluidic channels remains a challenge as channel structures often are clogged by residual cured resin. Dual‐curing systems based on off‐stoichiometric thiol‐ene and thiol‐ene/epoxy chemistry are well‐known for adhesive‐free bonding in the fabrication of cast or injection molded microfluidic devices. Herein, the first high‐resolution stereolithography 3D printing of a dual‐curing thiol‐ene/epoxy system in the microscale for the fabrication of customized microfluidic devices is presented. In the first curing step, by high‐resolution 3D printing open microfluidic structures are produced. Consecutively, the microchannels are sealed by adhesive‐free dry bonding upon thermal initiation, producing well‐controlled structures with channel sizes down to 80 µm. Before bonding, the intermediate material allows for tailored surface modification with biotin, which allows for consecutive immobilization of various biomolecules. A DNA‐bioassay with specific patterning is shown in the sealed chip. The presented work paves the way toward the fabrication of customized microfluidic devices for a large range of specific bioassays.
Advancing Monolithic Perovskite/TOPCon Tandem Solar Cells by Customizing Industrial‐Level Micro‐Nano Structures
Authors: Jiang Shengguo , Ding Zetao , Li Xin , Zhang Liping , Ying Zhiqin , Yang Xi , Yang Zhenhai , Yang Weichuang , Zeng Yuheng , Ye Jichun 
Published: April 2024

AbstractTexturing silicon solar cells with micro/nano‐structures is crucial for achieving outstanding optical performance in perovskite/silicon tandem solar cells (TSCs). However, ensuring excellent electrical properties remains a challenge due to reduced passivation quality of the bottom silicon sub‐cells and difficulties in perovskite formation on textured substrates. Here, an industrial‐level sub‐micron random pyramid (sMRP) structure on the front side of a tunnel oxide passivating contact (TOPCon) solar cell using a simple alkaline texturing process is presented, resulting in excellent optical and electrical properties. Through meticulous fabrication process tuning, uniform sMRP textures with a size of 0.6–0.8 µm are achieved, exhibiting low reflectance comparable to industrial‐level micron random pyramid (MRP) structures. Optimizing annealing temperatures of double‐sided TOPCon structures textured with front‐sided sMRP and rear‐sided MRP, yields high passivation quality, with a remarkable implied open‐circuit voltage (iVOC) of 713 mV. Furthermore, the sMRP‐textured surface facilitates the formation of a high‐quality perovskite film with larger grain sizes and fewer internal pinholes compared to the polished counterpart. Consequently, a proof‐of‐concept p‐i‐n typed perovskite/TOPCon TSC featuring sMRP textures obtains an outstanding efficiency of 28.67%, providing a promising approach for the commercial production of high‐efficiency perovskite/TOPCon TSCs.
Metal–Organic Framework‐Coated Glass Vials: A Step Forward in Analytical Platforms
Authors: Taima‐Mancera Iván , Trujillo‐Rodríguez María J. , Pasán Jorge , Pino Verónica 
Published: April 2024

AbstractA robust microextraction device in the form of a glass vial internally coated with metal–organic frameworks (MOFs) is designed, fabricated by in situ growth of different Zr‐based MOFs, and fully characterized for its novel use as an analytical platform. This device, uniformly coated by the MOF, ensures high simplicity and short times when used as an analytical microextraction tool, as the device acts as both the sample container and the extraction device, being tested for monitoring the presence of a group of endocrine‐disrupting chemicals in pool waters. The thin film format and MOF nature allow for high extraction efficiency and preconcentration of these target contaminants. Adsorption and desorption of the analytes are studied through kinetic experiments, with uptakes up to 90% for propylparaben in the UiO‐66‐abdc vial, and an extremely fast desorption in just seconds. The UiO‐66‐abdc vial does not require more than 15 min to perform a complete extraction‐desorption cycle, with limits of detection down to 0.10 µg L−1 in pool waters. The MOF‐coated vials are demonstrated to be easily (and highly) reusable by simple washing for a few min followed by drying. The simplicity of the method can be pushed further working in static mode or by a simple manual shaking.
Shaping the Infrared luminescence of Colloidal Nanocrystals Using a Dielectric Microcavity
Authors: Bossavit Erwan , Zhang Huichen , Ledos Nicolas , Cavallo Mariarosa , Mastrippolito Dario , Curti Leonardo , Khalili Adrien , Colle Albin , Lample Pierrick , Weis Mateusz , Margaillan Florent , Lafosse Xavier , Prado Yoann , Péronne Emmanuel , Pierucci Debora , Ithurria Sandrine , Boschetto Davide , Diroll Benjamin T. , Degiron Aloyse , Lhuillier Emmanuel 
Published: April 2024

AbstractAs they have gained maturity, colloidal nanocrystals (NCs) have also expand the spectral range over of which they could be used for photonic and optoelectronic applications. In particular, the infrared use of NCs has become of utmost interest to develop cost‐effective alternatives to current technologies. It is then critical not to let the material dictate the light–matter interaction, which is why the coupling of NCs to photonic cavities has been proposed. For infrared NCs, this approach has first been devoted to the control of absorption with in mind the increase of the signal magnitude for detectors. A Lot of efforts have been focused on the use of metallic metasurfaces. However, these generate significant optical losses and yield low quality factor. Here, this study rather focus on the coupling of infrared NCs to a dielectric mirror cavity. HgTe/CdS core‐shell NCs are used and integrated into a cavity made of aperiodic dielectric mirrors. The effect of the substrate is systematically study on spectral linewidth, carrier dynamic, and emission directivity. The cavity is shown to narrow the PL by a factor 10, while focusing the emission over a 12° angle. Monitoring the power dependence of the emission, this study shows that the cavity leads to 250 K increase in the effective electronic temperature.
Polarizable H‐Bond Concept in Aromatic Poly(thiourea)s: Unprecedented High Refractive Index, Transmittance, and Degradability at Force to Enhance Lighting Efficiency
Authors: Watanabe Seigo , Cavinato Luca M. , Calvi Vladimir , van Rijn Richard , Costa Rubén D. , Oyaizu Kenichi 
Published: April 2024

AbstractDeveloping transparent and highly refractive environmentally friendly polymers has not been realized yet toward sustainable optoelectronics. This work describes poly(thiourea)s (PTUs) design following a new “polarizable group synergy” concept, combining highly polarizable hydrogen bonding groups and aromatic‐based spacers to form densely packed and high‐refractive‐index polymer networks. Specifically, PTUs containing m‐ and p‐phenylene spacers exhibit an easy synthesis, high thermostability (Tg = 159 °C), visible transparency (>92%T at 1 µm‐film), ultra‐high refractive index (nD = 1.81) based on the random H‐bonding arrays with a high packing constant (Kp = 0.738), and straightforward preparation of flexible films via solvent‐based techniques. Capitalizing on these assets, PTU‐films are integrated into benchmark graphene‐based lighting device architectures based on the light‐emitting electrochemical cells (LECs) concept. A joint optical modeling and experimental validation confirm the increase in external quantum efficiency expected by the enhanced light out‐coupling of PTU‐films. Finally, PTUs are efficiently depolymerized to low molecular weight compounds by simply adding diamines under heating, following the dynamic covalent bond exchange between thiourea moieties. Overall, this work highlights the PTU family as new promising materials with a unique polarizable H‐bond design to meet efficient and sustainable thin‐film lighting devices.
Wavelength‐Linearly‐Dependent and Polarization‐Sensitive Perfect Absorbers based on Optically Anisotropic Germanium Selenide (GeSe)
Authors: Guo Zhengfeng , Gu Honggang , Yu Yali , Zhang Qihang , Wei Zhongming , Liu Shiyuan 
Published: April 2024

AbstractPerfect absorbers, widely utilized in solar energy‐harvesting devices, optical communications, sensors, displays, and filters, achieve 100% light absorption. However, perfect absorbers employing micro/nanostructures encounter challenges such as high cost and complexity in simulation and fabrication. Here, novel wavelength‐linearly‐dependent and polarization‐sensitive perfect absorbers utilizing optically anisotropic germanium selenide (GeSe) are proposed. A simple and cost‐effective GeSe‐SiO2‐Si multilayered optical thin film is constructed and optimized to achieve destructive interference, leading to perfect absorption. The operating wavelength can be linearly tuned from 900 nm to 1300 nm by adjusting the GeSe thickness from 125 nm to 200 nm. Leveraging the significant optical anisotropy, the polarization angle is introduced as an additional parameter to dynamically and finely control the operating wavelength, enabling the creation of polarization‐sensitive perfect absorbers. Experimental results validate the feasibility of fabricating and dynamically modulating the proposed wavelength‐linearly‐dependent and polarization‐sensitive perfect absorbers. This study introduces a novel approach for designing and fabricating reconfigurable perfect absorbers utilizing low‐symmetry materials, facilitating mass production and on‐chip integrated systems.
High‐Permittivity Polysiloxanes for Bright, Stretchable Electroluminescent Devices
Authors: von Szczepanski Johannes , Wolf Jana , Hu Wei‐Hsu , Schneider René , Danner Patrick M. , Kupferschmid André , Jenatsch Sandra , Hany Roland , Nüesch Frank A. , Opris Dorina M. 
Published: April 2024

AbstractStretchable alternating current electroluminescent (ACEL) devices have a bright future in wearable electronics and soft robotics. Still, their market application is hindered by high operating voltages. The voltage can be reduced by increasing the relative permittivity of the dielectric elastomer in the emissive layer. Here, a fluorine‐free high‐permittivity silicone elastomer functionalized with cyanopropyl side groups, specially designed for application in stretchable ACEL devices, is introduced. The polar silicone elastomer exhibits excellent mechanical properties and a dielectric permittivity four times higher than commercial PDMS. Light‐emitting devices based on the polar elastomer reach 7.5 times higher maximum luminance at the same electric field than PDMS‐based devices and turn on at a 50% lower electric field. Besides, the polar elastomer‐based devices perform better than all materials tested in literature in achieving high luminance at low electric fields. Stretchable ACEL devices are built from the polar elastomer which shows bright and uniform light emission and can be operated up to 50% strain. The high‐permittivity silicones are promising materials for stretchable ACEL devices and can help their breakthrough to market application by overcoming the drawback of high operating voltages.
Bi‐Functional Chelating Ligand Enables Ultra‐Stable Blue Emissive CsPbBr3 Nanoplatelets Film
Authors: Lin Hao , Gao Pei‐Li , Dong Jia‐Yi , Li Jie‐Lei , Lian Zhen‐Dong , Xu Jin‐Cheng , Ng Kar Wei , Chen Shi , Su Shi‐Chen , Liu Hong‐Chao , Wu Zhao‐Xin , Wang Shuang‐Peng 
Published: April 2024

AbstractQuantum‐confined perovskite CsPbBr3 Nanoplatelets (NPLs) have recently emerged as promising blue‐emitting materials for perovskite light‐emitting diodes (PeLEDs). Yet, their susceptibility to optical instability in solid films under ambient conditions poses a significant hindrance. This study introduces a novel chelating strategy that utilizes metal manganese ions and multidentate ligands, markedly improving the structural stability, and emission efficiency of NPLs. The approach involves adding Diethylenetriaminepentaacetic acid (DTPA) to the perovskite precursor solution, which allows for strong coordination to surface [PbBr6]4− octahedrons via its multiple chelation sites. Ensuing metal manganese ion integration during the purification phase addresses Pb2+ and Br− site vacancies, culminating in near‐perfect octahedral structures with significantly fewer vacancies. These metal manganese ions are then further immobilized on the NPLs surface by the chelating effect of unbound DTPA functional groups. The resultant CsPbBr3 NPLs films demonstrate an impressive PLQY of 66%, showcasing remarkable air stability with consistent blue emission for up to 5 days. The CsPbBr3 NPLs‐based PeLEDs show electroluminescence at 460 nm with a current efficiency of 1.07 cd A−1 and a maximum luminance of 220 cd m−2. The proposed chelating strategy positions perovskite NPLs as an extremely promising prospect in future applications of high‐definition displays and high‐quality lighting.
Formation of Anisotropic Conducting Interlayer for High‐Resolution Epidermal Electromyography Using Mixed‐Conducting Particulate Composite
Authors: Zhao Zifang , Yu Han , Wisniewski Duncan J. , Cea Claudia , Ma Liang , Trautmann Eric M. , Churchland Mark M. , Gelinas Jennifer N. , Khodagholy Dion 
Published: April 2024

AbstractEpidermal electrophysiology is a non‐invasive method used in research and clinical practices to study the electrical activity of the brain, heart, nerves, and muscles. However, electrode/tissue interlayer materials such as ionically conducting pastes can negatively affect recordings by introducing lateral electrode‐to‐electrode ionic crosstalk and reducing spatial resolution. To overcome this issue, biocompatible, anisotropic‐conducting interlayer composites (ACI) that establish an electrically anisotropic interface with the skin are developed, enabling the application of dense cutaneous sensor arrays. High‐density, conformable electrodes are also microfabricated that adhere to the ACI and follow the curvilinear surface of the skin. The results show that ACI significantly enhances the spatial resolution of epidermal electromyography (EMG) recording compared to conductive paste, permitting the acquisition of single muscle action potentials with distinct spatial profiles. The high‐density EMG in developing mice, non‐human primates, and humans is validated. Overall, high spatial‐resolution epidermal electrophysiology enabled by ACI has the potential to advance clinical diagnostics of motor system disorders and enhance data quality for human‐computer interface applications.