bluuebunny/crossref_metadata_2025_split huggingface dataset:
Lignin‐Derived Functional Carbon Framework for Homogeneous Sodium Deposition
Authors: Li Xiwei , Qi Yi , Lin Xuliang , Rui Xianhong , Qin Yanlin 
Published: March 2024

AbstractSodium metal batteries have become popular owing to their low redox potential, high theoretical capacity, and superior energy density. But the formation of sodium dendrites during electrochemical cycles diminishes the security and longevity of these batteries. In response to this challenge, we employ lignin as a carbon source to fabricate a three‐dimensional (3D) carbon framework current collector. This framework boosts an expansive specific surface area and a wealth of oxygen‐rich functional groups. These components serve to cushion the volume fluctuations of sodium metal throughout the electrochemical cycle, directing the even deposition of sodium ions. The as‐prepared anode displays a low overpotential of −7 mV and a stable cycling life of 400 hours at 0.5 mA cm−2. When coupled with Na3V2(PO4)3 cathode, the full cell can achieve a capacity of 97.6 mAh g−1 and a capacity retention of 94.7 % after 60 cycles. This research shows that using lignin as a carbon source to prepare a 3D carbon framework current collector is an effective mean to inhibit the harmful effects of sodium dendrites on batteries.
Mo‐Doped BiVO4 as a Fast Electrode Reaction Kinetics Catalyst in Na−O2 Batteries
Authors: Li Minglu , Wang Jiazhi , He Wei , Zhang Xiong , Zhang Huijuan , Ma Jinling , Wang Yu 
Published: March 2024

AbstractThe highly insulated solid discharge products in sodium‐oxygen (Na−O2) batteries induce large polarization and thus heavily threaten their cycle life. Controlment of discharge products taking efficient catalyst is a best way to solve this problem. Here, Mo‐doped BiVO4 as the catalyst produces large amounts of carrier, thus boosting the battery reaction and reducing the overpotential under the light assistance. Compared with the BiVO4 without Mo doping, the doped one has a lower recombination of photogenerated carriers, thus benefiting a large polarization suppression and Na−O2 batteries running for over 270 cycles under 3.65 V as well as a fine rate performance. Besides, Mo doping reduces the size of BiVO4, beneficial for the carrier transportation and more reactions due to the large specific surface area. Experiment combined with theoretical calculation shows that Mo doping is advantageous to enhancing catalytic activity of BiVO4 due to a lower work function for easier electron extraction, thus enhancing Na2O2 decomposition capability. This work undoubtedly inspires photocatalysts′ use for solving the insulated solid discharge products decomposition in metal‐O2 batteries and provides a guide for other photocatalysts possibilities.
The effect of phonics skills intervention on early reading comprehension in an adolescent with autism: A longitudinal study
Authors: Nicolosi Michael , Dillenburger Karola 
Published: March 2024

AbstractReading comprehension requires phonics skills, described as “blending phonemes in a word”. Adolescents diagnosed with Autism Spectrum Disorder (ASD) often experience poor reading comprehension. The aim of the present study was to explore if it is possible for an adolescent with ASD and intellectual disability to learn reading comprehension skills even without direct teaching, when the focus of the intervention is on teaching phonics skills. An adolescent with ASD, profound intellectual disability and limited behavioral repertoire participated in the study. The participant received intensive ABA‐based interventions according to University of California at Los Angeles‐Young Autism Project (UCLA‐YAP) model and intensive phonics training. Intervention data show emergence of early reading comprehension skills in terms of words/pictures matching and responding to written instructions. It is suggested that implementation of similar interventions could change the opportunities for people with autism who have limited behavioral repertoire and who did not begin an ABA‐based interventions until their adolescence.
Business strategies for achieving carbon neutrality goals in collaborative ecosystems: Bridging gaps in achieving operational status
Authors: Luqman Adeel , Zhang Qingyu , Sharma Veenu , Gugnani Ritika , Walsh Steven T. 
Published: March 2024

AbstractThis study delves into the pressing challenge of achieving carbon neutrality (CN) operational status among firms, with a specific focus on the moderating impact of emission scopes. We use mixed methods and ambidexterity and resource dependence theories to examine the relationships between four cooperation kinds (exploration‐focused, exploitation‐focused, resonance‐based, and governance‐centric) and firms' CN operating status. We also examine how three emission scopes affect cooperation and CN operating status. Our comprehensive research, based on primary and secondary data from 267 organizations, enhances our knowledge of how cooperation helps CNs achieve operational status. We find that stakeholder collaboration improves CN objectives. We found subtle correlations between collaboration types and emission scopes. Governance‐centric cooperation has a substantial interaction effect on scope 1 emissions, demonstrating its effectiveness in controlling emissions from owned or regulated sources. As the two emissions interact, the resonance‐based cooperation emphasizes the necessity of common values and beliefs between enterprises and stakeholders. With scope 3 emissions, exploitation‐focused cooperation emphasizes resource usage in emission management across the value chain and transportation. Exploration‐focused collaboration interacts with CN operational status for all three emission scopes, highlighting the importance of collaboration with research institutions, startups, and stakeholders in exploring emerging technologies and driving systemic changes for emission mitigation. Our study shows that stakeholder participation is crucial to CN operating status, especially for varied emission scopes. This research sheds light on collaborative strategy development and its importance in tackling varied emission scopes. Our research provides important contributions to the field, but future studies should understand its limits and examine the complexities of CN operational status and cooperation in other situations to increase knowledge.
Research progresses on metal‐organic frameworks for sodium/potassium‐ion batteries
Authors: Xin Ben‐Jian , Wu Xing‐Long 
Published: March 2024

AbstractMetal‐organic frameworks (MOFs), as a new type of functional material, have received much attention in recent years. High ionic conductivity, large specific surface area, controllable pore structure and geometry make it possible to be used as electrode materials. Meanwhile, different types of MOF derivatives can be prepared by adjusting the metal central element, which provides options for finding electrode materials for high‐performance batteries. This paper reviews the recent research progress of pristine MOFs for sodium/potassium‐ion batteries. In addition, this paper describes the working principle, advantages, and challenges of MOFs in sodium/potassium‐ion batteries, strategies to improve the electrochemical performance, as well as future prospects and directions.
Flavonoid Compounds in Hippophae rhamnoides L. Protect Endothelial Cells from Oxidative Damage Through the PI3K/AKT‐eNOS Pathway
Authors: Wang Mengyuan , Zhang Xingfang , Zhang Zonghao , Tong Li , Yu Song , Liu Yue , Yang Fang 
Published: March 2024

AbstractSea buckthorn, a traditional medicinal plant, has been used for several years in China for the prevention and treatment of various diseases, a practice closely associated with its significant antioxidant activity. The aim of this study was to investigate the protective effects of sea buckthorn flavonoids on vascular endothelial cells in an oxidative stress environment. We isolated and extracted active compounds from sea buckthorn and investigated their impact on endothelial nitric oxide synthase (eNOS) activity through the PI3K/AKT‐eNOS signaling pathway through a combination of network pharmacology and cellular experiments, elucidating the regulatory effects of these compounds on endothelial cell functions. Three flavonoids, named Fr.4‐2‐1, Fr.4‐2‐2 and Fr.4‐2‐3, were obtained from sea buckthorn. The results of network pharmacology indicated that they might exert their effects by regulating the PI3K‐AKT signaling pathway. In vitro results showed that all three flavonoids were effective in alleviating the degree of oxidative stress in cells, among which Fr.4‐2‐1 exerted its antioxidant effects by modulating the PI3K/AKT‐eNOS pathway. Flavonoids in sea buckthorn can effectively inhibit oxidative stress‐induced cellular damage, preserving the integrity and functionality of endothelial cells, which is crucial for maintaining vascular health and function.
Wenn Explosionsschutz auf Maschinensicherheit trifft
Authors: Lumme Rainer 
Published: March 2024

AbstractSicherheitsschaltgeräte, die unter Ex‐Schutz‐Bedingungen zum Einsatz kommen, müssen gleich zwei komplexe Regelwerke erfüllen, die Explosionsschutz‐ und die Maschinenrichtlinie. Der Konstrukteur hat auch die Wahl zwischen verschiedenen Bauarten und Wirkprinzipien. Das gilt sowohl für Heavy‐duty‐Anwendungen als auch für Maschinen, die z. B. (staub)explosionsgefährdete Lebensmittel verarbeiten oder verpacken.
Lastschutz für eine unterbrechungsfreie Anlagenverfügbarkeit
Authors: Bindner Michael 
Published: March 2024

AbstractFür die Automatisierung chemischer Prozessanlagen steigen die Anforderungen an eine zuverlässige Stromversorgung. Mit Stromverteilungsmodulen kann die Anlagenverfügbarkeit signifikant erhöht und die Anlage komfortabel überwacht werden. Ein intelligenter Lastschutz sorgt für den sicheren und unterbrechungsfreien Betrieb der Anlage.
Sicher mit dem Smartphone unterwegs
Authors: Uhl Christian 
Published: March 2024

AbstractMit der zunehmenden Automatisierung und Digitalisierung wird das Aufgabenspektrum der Beschäftigten in der Verfahrenstechnik immer komplexer und vielfältiger. Gleichzeitig gilt es Anlagenausfälle, die Kosten in Milliardenhöhe verursachen, durch vorausschauende Wartung um jeden Preis zu hindern. Dabei verraten intelligent analysierte und aggregierte Echtzeit‐Anlagendaten, wann etwa ein Bauteil ausgetauscht werden muss, um die Leistungsfähigkeit der Anlage zu jedem Zeitpunkt aufrecht zu erhalten.
Kleben statt schweißen
Authors: Wegmann Anton 
Published: March 2024

AbstractVibratoren oder Klopfer lösen Produktstauungen und unterstützen das Entleeren von Schüttgutbehältern. Das Nachzurüsten solcher Geräte ist insbesondere in explosionsgefährdeten Bereichen mit dem Einsatz von Schweißtechnik nur im Anlagenstillstand möglich. Hingegen reduziert der Einsatz von Klebetechnik die Stillstandzeit der Anlage und hat Vorteile beim Anbringen an dünnwandigen Behältern.
Adsorption Capacity of Carbon‐Silica Composites Towards Diclofenac in Poly(acrylic acid) Containing Systems: A Crucial Study on Common Wastewater Contaminants
Authors: Medykowska Magdalena , Wiśniewska Małgorzata , Szewczuk‐Karpisz Katarzyna , Galaburda Mariia 
Published: March 2024

AbstractDiclofenac is one of the most popular over‐the‐counter non‐steroidal anti‐inflammatory drug and poly(acrylic acid) is a frequently used as thickener, filler or stabilizer. For these reasons, they are common organic contaminants in raw wastewater. The purpose of the presented studies was to compare the adsorption capacity of three carbon‐silica composites – metal‐free C/SiO2, iron‐enriched C/Fe/SiO2 and manganese‐enriched C/Mn/SiO2 towards diclofenac. The studies were carried out in single, and mixed systems in the presence of poly(acrylic acid) polymer. Adsorption, desorption and kinetics of the adsorption process were investigated. The concentration of diclofenac in the supernatants was determined using high‐performance liquid chromatography. The solids were also characterized with an ASAP apparatus using low‐temperature nitrogen desorption adsorption isotherms at liquid nitrogen temperature. In addition, potentiometric titrations and electrophoretic mobility measurements, as well as stability tests of the studied suspensions were carried out. The most efficient composite among investigated ones proved to be C/Fe/SiO2 removing diclofenac at the level of 46.68 mg/g for its initial concentration of 90 ppm. The results obtained clearly demonstrated that the carbon‐silica composites are effective in separation of drugs from aqueous solutions and can be successfully used in the future for the removal of organic pollutants from water environment.
MicroRNA‐20a in extracellular vesicles derived from duodenal fluid is a possible biomarker for pancreatic ductal adenocarcinoma
Authors: Taniguchi Takashi , Ideno Noboru , Araki Tomoyuki , Miura Shun , Yamamoto Masahiro , Nakafusa Tomoki , Higashijima Nobuhiro , Yamamoto Takeo , Tamura Koji , Nakamura So , Abe Toshiya , Ikenaga Naoki , Nakata Kohei , Ohuchida Kenoki , Oda Yoshinao , Ohtsuka Takao , Nakamura Masafumi 
Published: March 2024

AbstractBackgroundPancreatic ductal adenocarcinoma (PDAC) has a high mortality rate owing to its late diagnosis and aggression. In addition, there are relatively few minimally invasive screening methods for the early detection of PDAC, making the identification of biomarkers for this disease a critical priority. Recent studies have reported that microRNAs in extracellular vesicles (EV‐miRs) from bodily fluids can be useful for the diagnosis of PDACs. Given this, we designed this study to evaluate the utility of cancer EVs extracted from duodenal fluid (DF) and their resident EV‐miRs as potential biomarkers for the detection of PDAC.MethodsEV‐miRs were evaluated and identified in the supernatants of various pancreatic cancer cell lines (Panc‐1, SUIT2, and MIAPaca2), human pancreatic duct epithelial cells, and the DF from patients with PDAC and healthy controls. EVs were extracted using ultracentrifugation and the relative expression of EV‐miR‐20a was quantified.ResultsWe collected a total of 34 DF samples (27 PDAC patients and seven controls) for evaluation and our data suggest that the relative expression levels of EV‐miR‐20a were significantly higher in patients with PDAC than in controls (p = 0.0025). In addition, EV‐miR‐20a expression could discriminate PDAC from control patients regardless of the location of the tumor with an area under the curve values of 0.88 and 0.88, respectively.ConclusionsWe confirmed the presence of EVs in the DF and suggest that the expression of EV‐miR‐20a in these samples may act as a potential diagnostic biomarker for PDAC.
Decoding the potential role of regulatory T cells in sepsis‐induced immunosuppression
Authors: Huang Siyuan , Liu Di , Han Lei , Deng Jin , Wang Zhen , Jiang Jianxin , Zeng Ling 
Published: March 2024

AbstractSepsis, a multiorgan dysfunction with high incidence and mortality, is caused by an imbalanced host‐to‐infection immune response. Organ‐support therapy improves the early survival rate of sepsis patients. In the long term, those who survive the “cytokine storm” and its secondary damage usually show higher susceptibility to secondary infections and sepsis‐induced immunosuppression, in which regulatory T cells (Tregs) are evidenced to play an essential role. However, the potential role and mechanism of Tregs in sepsis‐induced immunosuppression remains elusive. In this review, we elucidate the role of different functional subpopulations of Tregs during sepsis and then review the mechanism of sepsis‐induced immunosuppression from the aspects of regulatory characteristics, epigenetic modification, and immunometabolism of Tregs. Thoroughly understanding how Tregs impact the immune system during sepsis may shed light on preclinical research and help improve the translational value of sepsis immunotherapy.
Retinoic acid‐loaded liposomes induce human mucosal CD103+ dendritic cells that inhibit Th17 cells and drive regulatory T‐cell development in vitro
Authors: Nagy Noémi Anna , Hafkamp Florianne M. J. , Sparrius Rinske , Bas Rico , Lozano Vigario Fernando , van Capel Toni M. M. , van Ree Ronald , Geijtenbeek Teunis B. H. , Slütter Bram , Tas Sander W. , de Jong Esther C. 
Published: March 2024

AbstractThe active vitamin A metabolite, all‐trans‐retinoic acid (RA), primes precursor dendritic cells (DCs) into a mucosal phenotype with tolerogenic properties characterized by the expression of integrin CD103. CD103+ DCs can counteract pathogenic Th1 and Th17 in inflammatory bowel disease (IBD) or celiac disease (CD). Tolerogenic manipulation of DCs using nanoparticles carrying tolerogenic adjuvants and disease‐specific antigens is a valuable treatment strategy to induce antigen‐specific mucosal tolerance in vivo. Here, we investigated the effects of RA‐loaded liposomes on human DC phenotype and function, including DC‐driven T‐cell development, both during the generation of monocyte‐derived DCs (moDCs) as well as by priming immature moDCs. RA liposomes drove CD103+ DC differentiation as well as ALDH1A2 expression in DCs. Neutrophil‐dependent Th17 cell development was reduced by RA‐liposome‐differentiated and RA‐liposome‐primed DCs. Moreover, RA liposome treatment shifted T‐cell development toward a Th2 cell profile. Importantly, RA liposomes induced the development of IL‐10‐producing and FoxP3+ regulatory T cells (Tregs) of various Treg subsets, including ICOS+ Tregs, that were potent inhibitors of bystander memory T‐cell proliferation. Taken together, RA‐loaded liposomes could be a novel treatment avenue for IBD or CD patients.
Influence of storage temperature and natural antioxidants addition on chia oil nutraceutical blends shelf life
Authors: Spotti María Laura , Acosta Carolina Anabella , Carrara Carlos Roberto , Fioramonti Silvana Alejandra 
Published: March 2024

AbstractThis study focuses on the influence of storage temperature and addition of commercial natural antioxidant‐rich sources on the shelf life of chia oil (CO) nutraceutical blends. CO is a valuable product for consumers due to its high ω‐3 content, but its susceptibility to oxidation comprises challenges for its shelf life and quality. Thereby, different chia oil‐antioxidant blends were prepared and stored at 4°C and 25°C to evaluate alternative shelf‐life conditions. Commercial antioxidant‐rich sources containing astaxanthin (ASX), β‐carotene (BC) and vitamin E (VE) were added either alone or combined to CO. To monitor blends oxidative stability during storage, primary and secondary oxidation compounds were assessed weekly using peroxide value (PV) and thiobarbituric acid reactive substances (TBARS) as indicators. Results showed that storage temperature played a significant role on oxidative stability of CO. When stored under refrigeration at 4°C, the oil exhibited low and stable oxidation indicators over time, regardless of the antioxidants used. However, at room temperature (25°C), the use of antioxidants and some particular combinations of them became crucial to prevent oil oxidative deterioration. Nutraceutical blends of CO/BC and CO/ASX were the best options to preserve CO from oxidation after 8 weeks storage at room temperature (PV < 2 meq O2/kg oil).Practical Applications: This work provides evidence on enhancing oxidative stability of chia oil through addition of natural antioxidants and proper storage. We focused primarily on designing blends from edible ingredients that are currently available in the market, with the aim of ensuring easy accessibility and affordability. Our findings offer valuable insights for the development of chia oil and antioxidant‐enriched blends, that could potentially serve as nutraceuticals or pharmacy‐compounded supplements to manage specific chronic inflammatory diseases. Our study highlights the importance of considering storage temperature and antioxidant selection to enhance shelf life and quality. These results have significant implications for the food industry, nutrition, and health, by providing valuable information for the creation of healthier and more sustainable food products. Furthermore, this work underscores the need for companies and retailers handling and storing vegetable oils with high omega‐3 content to adopt improved storage practices to ensure the quality and longevity of their products.
Development and verification of real‐time hybrid simulation with deep learning‐based nonlinear numerical substructure
Authors: Chen Pei‐Ching , Hsu Shang‐Chi , Ma Chung‐Chun 
Published: March 2024

AbstractReal‐time hybrid simulation (RTHS) provides an effective approach for assessing structural responses under dynamic excitation. However, performing RTHS with a complex nonlinear numerical substructure is challenging, as computations must be completed within predefined time steps. In this study, a RTHS framework which contains a rate‐dependent experimental substructure and a nonlinear numerical substructure has been proposed and verified. An OpenSees model was constructed to simulate a three‐story, one‐bay steel building with viscous dampers at each floor and was used to generate the training dataset through a large number of nonlinear time‐history analyses. A Recursive Long Short–Term Memory (LSTM) neural network model was trained to predict the nonlinear structural responses using ground acceleration and time‐delayed damper force located at the first story. Hence, the Recursive‐LSTM model served as a surrogate model for the numerical substructure, implicitly incorporating delay compensation for the experimental substructure. After the training was completed, offline testing was performed to realize the stability of the RTHS framework. Then, online RTHS with a virtual damper taken as the experimental substructure was conducted to further confirm the feasibility and accuracy. Afterwards, a nonlinear rotary fluid viscous damper (RFVD) was fabricated as the actual experimental substructure, whose dynamic response was not considered in training the Recursive‐LSTM model. Finally, RTHS with the RFVD was completed successfully and stably, demonstrating the capability of a well‐trained Recursive‐LSTM model to serve as a nonlinear numerical substructure incorporating constant delay compensation for RTHS. The potential of the proposed RTHS framework is worth further studies in the future.
Long‐term fracture conductivity in tight reservoirs
Authors: Yan Chuanliang , Zhang Penghui , Dong Leifeng , Zhang Chuang , Cheng Yuanfang 
Published: March 2024

AbstractReservoir stimulation using hydraulic fracturing technology is one of the most common stimulation measures to develop tight oil and gas reservoirs, and the conductivity of fractures after fracturing is the key to the stimulation effect of oil fields. In this paper, the laboratory simulation system of fracture conductivity is used to study the long‐term fracture conductivity under the displacement of formation water and fracturing fluid. The experimental results show that the fracture conductivity decreases with the increase of displacement time under the displacement of formation water and fracturing fluid, and the decrease of fracture conductivity under the displacement of fracturing fluid with time is greater than that of formation water displacement because of the plugging effect of fracturing fluid residue on pore channels. The use of formation water and fracturing fluid circulation displacement can delay the decline rate of conductivity with time. The conductivity increases with the increase of sand concentration, proppant particle size, and elastic modulus, and decreases with the increase of closure pressure. In addition, by studying the influence of elastic modulus on fracture width, it is found that the smaller the elastic modulus is, the more serious the embedding phenomenon of proppant is, and the smaller the fracture width is.