bluuebunny/crossref_metadata_2025_split huggingface dataset:
Mapping molecular diffusion across the whole cell with spatial statistics-based FRAP
Authors: Okabe Yohei , Saito Takumi , Nakashima Outa , Matsunaga Daiki , Deguchi Shinji 
Published: February 2025

AbstractUnderstanding molecular diffusion within cells is crucial for gaining insights into cellular biophysical mechanisms. Fluorescence recovery after photobleaching (FRAP) is a powerful technique for assessing molecular diffusion, yet its localized measurement approach hinders whole-cell analysis. To overcome this limitation, we developed Probabilistic FRAP (Pro-FRAP), a novel approach that integrates FRAP with sequential Gaussian simulation (SGS), an advanced spatial statistical method incorporating probabilistic modeling to estimate diffusion in unmeasured regions. Pro-FRAP applies SGS to standardize measured FRAP data, perform conditional simulations based on spatial correlations, and generate statistically robust estimates. In separate analyses, numerical simulations were conducted to optimize the spatial arrangement of measurement points, enhancing data accuracy and coverage. Unlike deterministic interpolation methods, Pro-FRAP captures spatial variability and quantifies uncertainty in intracellular diffusion, providing a more detailed representation of molecular transport. Thus, this framework extends FRAP beyond localized measurements, offering a refined approach for mapping intracellular diffusion with improved spatial coverage and statistical reliability.Significance statementUnderstanding molecular diffusion is essential for deciphering cellular functions and regulation. However, conventional fluorescence recovery after photobleaching (FRAP) techniques are constrained to localized measurements, limiting their ability to capture diffusion dynamics across entire cells. Here, we describe Probabilistic FRAP (Pro-FRAP), a novel framework that integrates FRAP with sequential Gaussian simulation (SGS), a spatial statistical method that enables the estimation of molecular diffusion in unmeasured regions. By incorporating probabilistic modeling, Pro-FRAP generates high-resolution diffusion maps with enhanced statistical reliability. This approach provides a more comprehensive perspective on intracellular transport, allowing for deeper insights into the spatial organization of cellular processes.
Outcome payer perspectives on social impact bonds as mediating instruments
Authors: Pullen Tim , Smith David , Humphrey Jacquelyn , Benson Karen 
Published: February 2025

PurposeThe purpose of this paper is to examine how the practices, processes and expertise embedded within Social Impact Bonds (SIBs) distinctively mediate the tensions between outcome payers’ competing and contradictory programmatic discourses.Design/methodology/approachWe use qualitative research methods and employ concepts drawn from the governmentality literature to analyse interviews with SIB outcome payers.FindingsSIBs are shown to challenge the degree of negative influence of biopolitics, neoliberalism and financialization by highlighting a broader and more holistic set of influences. SIB operations pre-empt and counteract perceived risks and are refined through a “learning by doing” effect. In contrast to other approaches to funding social interventions, the SIB structure attributes and independently validates outcomes. Payments to investors are based on the achievement of outcomes and are funded by the outcome payers. SIBs’ operational processes allow the responsibilities of the various parties to be explicitly assigned and contracted. The interests are aligned, yet the cultural differences harnessed.Originality/valueThis paper is one of the first to apply governmentality concepts to SIBs. By focusing on outcome payers, the paper provides new perspectives on the practices, processes and expertise of governing and the programmatic discourses of governing, as well as their relationship. The insights offered are supported by one of the largest and most diverse empirical SIB samples including 34 interviews where 43 individuals reflect on their experiences across 32 unique outcome payer organisations.
Importance of repayment capacity in the quantitative rationing of agricultural credit in Benin
Authors: Assogba Kpossou Adjoua Roxène Priscille , Babadankpodji Adjoua Pascaline Ida , Gandonou Esaïe , Aoudji Augustin , Zannou Afio , Biaou Gauthier 
Published: February 2025

PurposeThis paper analyzes the effect of repayment capacity on the quantitative rationing of credit to agricultural credit applicants.Design/methodology/approachThe empirical analysis of credit supply involved 595 applicants for agricultural credit. The instrumental variable (IV) approach of probit and tobit was used to identify credit rationing factors.FindingsAll things being equal, a 1% increase in repayment capacity increases the amount received by 25% for large applicants, and 47% for small applicants. Other variables related to equity, participation rate, crops produced, reputation, age, activity stability and proximity influence the credit supply.Research limitations/implicationsThe results of this study provide a theoretical basis for comparing small and large agricultural credit applicants, which is essential for better decision-making by financial institutions and the government. This article recommends that all applicants should have a good reputation and keep their business income and expenditure book up-to-date, that small applicants should invest in their business and improve their financial education and that large applicants should accumulate wealth and invest in perennial crops. As a limitation of this study, it would be possible to extend the data to other institutions using panel data.Originality/valueThe originality of this study lies in its consideration of the endogeneity problem between repayment capacity and credit rationing and, in a comparative analysis of small and large credit applicants. The results of this analysis will be used to adjust agricultural credit granting policies.
Amalgamating 4.0 technologies and traceability: exploring business value in food chains
Authors: Falcetti Izabela Postingel , Lago da Silva Andrea , Queiroz Maciel M. 
Published: February 2025

PurposeOver recent years, public health threats, economic losses and crises of confidence resulting from adverse events along the global food chains have pressured food traceability systems to operate more efficiently. Based on that, this paper aims to expand the body of knowledge on the connection between Industry 4.0 technologies and food chain traceability and how they have been integrated.Design/methodology/approachBefore conducting a systematic literature review (SLR), we consulted academic experts in traceability and Industry 4.0 technologies to define the leading 4.0 technologies adopted. We then developed protocols and criteria for article selection. Based on the developed codebook, we performed a content analysis, refining it through discussions with experienced researchers.FindingsThis paper identified seven Industry 4.0 technologies applied in conjunction with support and device systems. These combinations hold promise for generating value for food chain traceability systems. Value for the food supply chain originates from five sources: trust, process improvement, data processing, security, sustainability and regulation. Besides, three barriers to implementing such traceability technologies were identified: resources, lack of structure, stakeholders and values.Research limitations/implicationsWhile this study focused specifically on the food chain, the technology combinations, values, barriers and categories identified herein can inform analyses for other chains, e.g. the pharmaceutical chain. Moreover, due to the recent growth of this topic, some existing values and barriers may not have been fully explored and the technology combinations may vary slightly.Practical implicationsThe results of this study provide food chain professionals with a comprehensive understanding of the values and corresponding barriers associated with employing Industry 4.0 traceability technologies. This knowledge can be leveraged to develop effective strategies and implement improvements in traceability, thereby benefiting society and addressing identified barriers.Originality/valueThis study expands the literature on using Industry 4.0 technologies for traceability in food chains, providing valuable directions to build safer, more efficient, transparent and potentially more sustainable food chains. Additionally, we provide promising avenues for future research.
Impact of food waste-related course attendance on students’ food waste reduction behaviours and knowledge: a case study from Indonesia
Authors: Sitompul Carles , Gunawan Theresia , Mesiranta Nina , Närvänen Elina , Octavia Johanna Renny 
Published: February 2025

Purpose
This study aims to examine food waste behaviours among university students in Indonesia by adapting the theory of planned behaviour (TPB) alongside the theory of domains of knowledge.

Design/methodology/approach
A total of 518 students at five Indonesian universities participated in an online survey, answering questions about their food waste behaviours based on the TPB and the domains of knowledge frameworks. Among them, 250 students had taken a course that covered the food waste topic, while 268 students had not taken the course. The data were later analysed by using partial least squares-structural equation modelling and measurement invariance across the composite models.

Findings
The findings reveal that environmental awareness, attitude towards food waste behaviours, subjective norms and different types of knowledge which are procedural knowledge, declarative knowledge, personal and social knowledge significantly influence food waste behaviour. Students who attended a course related to the food waste topic were more likely to align their intentions to reduce food waste with their reduction behaviour.

Originality/value
While previous research has highlighted the importance of the TPB in understanding food waste intentions and behaviour, studies also show that students’ knowledge about food waste plays a crucial role in shaping these intentions. This study builds on these insights by combining the TPB with the domains of knowledge theory, specifically looking at how participating in food waste-related courses influences food waste behaviours among Indonesian students.
Data systems in supply chain resilience: moderated moderating effects of enterprise resource planning
Authors: Sadeghi R Kiarash , Ojha Divesh , Azadegan Arash 
Published: February 2025

PurposeOutsourcing and offshoring practices have introduced a high level of complexity into operations and supply chains, involving suppliers and manufacturers from various locations to deliver value to final customers within an integrated information-sharing system such as enterprise resource planning (ERP). Such supply chains have been facing more cyberattacks, a ubiquitous problem and danger to businesses worldwide. Therefore, the research objective addresses these research questions: “What is the role of complexity in building cyber-resilience in supply chains? What is the role of ERP in complex supply chains?”Design/methodology/approachThis paper proposes a research model that is empirically tested along with robustness tests such as endogeneity. To provide empirical data, this paper focused on supply chain relationships as the unit of analysis. The sample is selected from the USA employee population with experience in operations management and information technologies.FindingsThe findings indicate that ERP systems assist supply chains in reducing the adverse effects of downstream complexity on the efficacy of information sharing within secure systems for creating cyber resilience. Moreover, theoretical development showed that the more complex the supply chains are, the harder it is to create rents.Practical implicationsThe findings underscore the importance of implementing cybersecurity frameworks such as ISO 27001, as well as regular training to mitigate threats such as phishing and social engineering. Despite the initial costs, such investments are vital for minimizing potential losses from breaches, which are estimated to cost around $4m on average globally.Social implicationsThis research reveals the social impacts of supply chain cyber resilience through ERP systems, which emphasize the protection of consumer data, job security and public confidence. Cyber resilience and ERP systems help shield against data breaches, preserving privacy, preventing job losses and maintaining trust between people and industrial sectors.Originality/valueThe contribution is to propose the moderated moderating role of ERP in cyber resilience. This paper investigates the interaction effects of ERP and downstream complexity on the relationship between information sharing and cyber resilience. Moreover, this paper develops the relational view to consider the influential impacts of complexity in creating rents.
Innovative approaches to mental health care in Pakistan: perspectives from a nonprofit organization
Authors: Dayani Komal , Mughis Waliyah , Ali Uswa , Hashim Shahzor , Nafees Beenish , Sabri Taha 
Published: February 2025

Purpose
Pakistan faces a high burden of mental illness, yet mental health care remains underprioritized. This paper aims to examine key challenges within Pakistan’s mental health-care system, such as inadequate infrastructure, stigma and limited access to mental health care. It highlights how a nonprofit organization addresses these issues using a multifaceted approach.

Design/methodology/approach
This perspective explores a comprehensive strategy that includes public awareness campaigns to reduce stigma, telephonic mental health services to enhance accessibility to mental health care and advocacy efforts to promote systemic change.

Findings
The integration of these approaches has the potential to improve mental health awareness, increase accessibility through a national helpline and develop community programs offering both digital and in-person support. These efforts demonstrate the promise of synchronous interventions to address mental health challenges effectively.

Originality/value
This paper provides a unique perspective on addressing mental health challenges in low-resource settings like Pakistan. It emphasizes the synergy of combining awareness, direct mental health support and advocacy efforts to create a scalable and sustainable mental health ecosystem while highlighting lessons applicable to other low-resource settings globally.
Count on me! Accounting consultancy for small businesses
Authors: do Nascimento Silva Cíntia , Pereira de Castro Casa Nova Silvia 
Published: February 2025

PurposeTo characterize the consulting services provided by accountants to owner-managers of small businesses (OMSBs) in Brazil, addressing a significant gap in existing research.Design/methodology/approachA qualitative approach was employed, conducting 23 semi-structured interviews with OMSBs and specialists, analyzed using grounded theory techniques from an interpretivist perspective.FindingsThe study identifies three categories of accounting consultancy: tools, advisory and training. Accountant-consultants act as integrators, bridging diverse knowledge domains for less professionally managed businesses and connecting various resources or advisory professionals for more structured ones. Preparation in multiple areas, especially management, is considered crucial, alongside fostering trust and using clear, simple language. Collective consultancy and specialization in specific segments are suggested as mechanisms to ensure the economic viability of providing these services.Research limitations/implicationsThe study provides insights into the nature of accounting consultancy for small businesses in Brazil but may not capture the full spectrum of practices across different regions or industries. Future research could explore these variations for a more comprehensive understanding.Originality/valueThis study addresses a significant gap in the literature by providing a detailed understanding of the consulting services offered by accountants to small businesses in Brazil, offering practical insights for both professionals and policymakers aiming to support this vital sector of the economy.
Exploring the feasibility and acceptability of digital reminiscence therapy for people with dementia in Jordanian care homes: a qualitative study
Authors: Abdalrahim Asem 
Published: February 2025

Purpose
This study aims to explore the feasibility and acceptability of digital reminiscence therapy (RT) using touchscreen technology for people with dementia (PwD) in Jordanian care homes.

Design/methodology/approach
Semi-structured interviews were conducted with 14 residents and 7 care home staff.

Findings
Thematic analysis revealed four key themes: ease of use, supportive environment, engaging content and perceived positive impacts on quality of life (QoL). Participants highlighted enhanced communication, improved cognitive abilities and psychological well-being as primary benefits.

Research limitations/implications
These findings underscore the potential of digital RT to improve dementia care while adapting interventions to sociocultural contexts.

Originality/value
This study offers original insights into the feasibility and acceptability of digital RT in a Middle Eastern context, focusing on PwD in Jordanian care homes. By addressing the unique cultural and resource limitations of low- and middle-income countries, the study highlights the potential of culturally adapted, technology-enabled interventions to enhance QoL, communication and emotional well-being for PwD. The findings provide valuable guidance for practitioners and policymakers on integrating digital RT into dementia care practices, making a significant contribution to the global discourse on innovative, non-pharmacological approaches for older populations.
Food waste is embarrassing! Motivations and actions to prevent it among students in Italy
Authors: Palmieri Nadia , Boccia Flavio 
Published: February 2025

Purpose
According to recent studies, young people are most inclined to waste food, and an important category is represented by students. Unlike other young people, they possess several characteristics that influence their food waste behaviour. For these reasons, this study aims to identify the elements that influence students’ behaviour towards food waste in Italy to provide insights on how to reduce food waste among young consumers.

Design/methodology/approach
In this exploratory research, a Web survey involving 1,066 Italian students was used, and, after a factor analysis, a hierarchical multiple linear regression model was applied.

Findings
The findings showed that, at a young age, the food thrown away and the reasons are positively associated with food waste, while the family size and the actions that students adopt to prevent food waste are negatively associated with it.

Practical implications
Recognizing that students are the people who will shape the food waste scenario of the future, it is important to implement educational paths about it and to raise consumer awareness. The findings might provide interesting insights on how to develop educational campaigns for specific target groups, such as students. In fact, the results underline that local institutions and retailers should be involved in educational campaigns aimed at both addressing the motivations behind food waste and improving the actions people take to prevent it.

Originality/value
The paper revisits the issue using a relatively large sample of Italian students (youths aged 16–18 years). The results provide valuable insights on how to approach hypothetical Italian students in view of the potential development of new strategies for reducing food waste.
A split ribozyme system for in vivo plant RNA imaging and genetic engineering
Authors: Liu Yang , Rajput Ruchika , Islam Md Torikul , Valle Ilenne Del , Yao Tao , Agrawal Rekha , Boone Brandon A. , Eckert Carrie A. , Abraham Paul E. , Chen Jin‐Gui , Tuskan Gerald A. , Yang Xiaohan 
Published: February 2025

SummaryRNA plays a central role in plants, governing various cellular and physiological processes. Monitoring its dynamic abundance provides a discerning understanding of molecular mechanisms underlying plant responses to internal (developmental) and external (environmental) stimuli, paving the way for advances in plant biotechnology to engineer crops with improved resilience, quality and productivity. In general, traditional methods for analysis of RNA abundance in plants require destructive, labour‐intensive and time‐consuming assays. To overcome these limitations, we developed a transformative innovation for in vivo RNA imaging in plants. Specifically, we established a synthetic split ribozyme system that converts various RNA signals to orthogonal protein outputs, enabling in vivo visualisation of various RNA signals in plants. We demonstrated the utility of this system in transient expression experiments (i.e., leaf infiltration in Nicotiana benthamiana) to detect RNAs derived from transgenes and tobacco rattle virus, respectively. Also, we successfully engineered a split ribozyme‐based biosensor in Arabidopsis thaliana for in vivo visualisation of endogenous gene expression at the cellular level, demonstrating the feasibility of multi‐scale (e.g., cellular and tissue level) RNA imaging in plants. Furthermore, we developed a platform for easy incorporation of different protein outputs, allowing for flexible choice of reporters to optimise the detection of target RNAs.
New Electro-Active Polymers-Based Plasma Actuators for Simultaneous Flow Control and Ice Protection
Authors: Mbanguine L. A. , Rodrigues F. F. , Páscoa J. C. 
Published: February 2025

Abstract
The current work introduces a new device for effective flow control and ice removal applications based on the combination of a nonthermal plasma discharge with the excitation of an electro-active polymer membrane. This new device designated electro-active polymer (EAP) plasma actuator is particularly interesting for aeronautic and wind power applications since it allows to perform simultaneous flow control and ice removal operations. To prove the concept, in the current work, an electro-active polymer-based plasma actuator device is fabricated and experimentally tested. For the initial tests a “VHB 4910” from 3 M was used as dielectric layer and electrically conductive grease was utilized to fabricate the flexible electrodes. The results demonstrate that this new concept is feasible, and the EAP plasma actuator is able to elongate up to 80% for an applied voltage of 7 kV. In addition, it is proved it can generate induced flow velocities above 2 m/s and, simultaneously, it is able to increase the surface temperature above 100 °C. In comparison to conventional plasma actuator, the new EAP actuator brings several other advantages mainly for de-icing purposes since the electro-active polymer movement will difficult the ice adhesion and help to expel the ice from the surface.