bluuebunny/crossref_metadata_2025_split huggingface dataset:
Double Carbonylation Reactions of Enynols and Thiols to Form Thioester Substituted 6‐Membered Ring Lactones
Authors: Cao Hong , Xiao Wen‐Jing , Alper Howard 
Published: September 2006

AbstractThe double carbonylation reaction of enynols with thiols affords functionalized 6‐membered ring lactones. Two kinds of 6‐membered ring lactones were obtained by the use of different palladium complexes with added phosphine ligands.
Elejalde syndrome—A case report
Authors: Šilhánová Eva , Plevová Pavlína , Čuřík Romuald , Kasperčík Ivo , Křepelová Anna 
Published: September 2006

AbstractElejalde syndrome (McKusick 200995), also known as acrocephalopolydactylous dysplasia, is a rare condition. We describe a sixth patient with this syndrome which is characterized by craniosynostosis and hyperproliferation of fibroblasts in many tissues including skin, liver, kidney, and pancreas. The cause of the syndrome is the homozygous state of an autosomal recessive mutation. We present a hypothesis that Elejalde syndrome might be associated with an inactivating FGFR gene mutation. © 2006 Wiley‐Liss, Inc.
Festschrift for Dr. John M. Opitz: Pathogenesis of cardiac conduction disorders in children genetic and histopathologic aspects
Authors: Gilbert‐Barness Enid , Barness Lewis A. 
Published: September 2006

AbstractFetal dysrhythmias are usually transient. Abnormal fetal rates and rhythms during labor are “functional.” Fetal dysrhythmias may be associated with congenital heart disease and fetal hydrops. Bradycardia is usually related to fetal distress; supraventricular tachycardia, atrial flutter, and atrial fibrillation may be associated with severe congestive heart failure. Ventricular fibrillation is rare in the fetus and infant and is usually associated with myocardial necrosis with perimembranous septal defect; the nonbranching atrioventricular (AV) bundle may have an aberrant position and result in cardiac arrhythmia. Wolff–Parkinson–White syndrome with conduction abnormalities and left ventricular hypertrophy (LVH) is due to an accessory pathway that bypasses the AV sulcus and results in faster conduction. Carnitine deficiency may be primary or secondary and may result in cardiac arrhythmia. Histiocytoid cardiomyopathy is characterized by cardiomegaly, incessant ventricular tachycardia, and frequently sudden death. Arrhythmogenic right ventricular dysplasia (ARVD) results in ventricular tachycardia and left bundle branch block. Noncompaction of the left ventricle predisposes to potentially fatal arrhythmias. Long Q‐T syndromes (LQTS) are a heterogeneous group of disorders with many genetic mutations. Brugada syndrome is an autosomal dominant trait with right bundle branch block and ST elevation. Barth syndrome is an X‐linked disorder with dilated cardiomyopathy, cyclic neutropenia and skeletal myopathy. Hypertrophic cardiomyopathy in infancy may be related to metabolic diseases, particularly glycogen storage diseases; the familial form predisposes to sudden death. Arrhythmias following cardiac surgery may occur after closure of a ventricular septal defect (VSD) or damage to the conduction system. © 2006 Wiley‐Liss, Inc.
A fourth locus for hereditary hemorrhagic telangiectasia maps to chromosome 7
Authors: Bayrak‐Toydemir Pinar , McDonald Jamie , Akarsu Nurten , Toydemir Reha M. , Calderon Fernanda , Tuncali Timur , Tang Wei , Miller Franklin , Mao Rong 
Published: September 2006

AbstractHereditary hemorrhagic telangiectasia (HHT) is a genetically and clinically heterogeneous multisystem vascular dysplasia. Mutations of the endoglin and ACVRL1 genes are known to cause HHT. However, existence of HHT families in which linkage to these genes has been excluded has suggested that other gene(s) can cause HHT in some families. Recently, a family was reported to be linked to chromosome 5q, the HHT3 locus. Here we report on linkage results on a family with classic features of HHT, albeit a less severe phenotype with regards to epistaxis and telangiectases, in which linkage to HHT1, HHT2, and HHT3 is ruled out. Whole genome linkage analysis and fine mapping results suggested a 7 Mb region on the short arm of chromosome 7 (7p14) between STR markers D7S2252 and D7S510. We obtained a maximum two point LOD score of 3.60 with the STR marker D7S817. This region was further confirmed by haplotype analysis. These findings suggest the presence of another gene causing HHT (HHT4). The features in this family that strongly suggest the presence of a hereditary, multisystem vascular dysplasia would be easily missed during the typical evaluation and management of a patient with an AVM. This family helps emphasize the need to obtain a very detailed, targeted medical and family history for even mild, infrequent but recurring nosebleed, subtle telangiectases. Further studies of the candidate region and the identification of the gene responsible for the vascular anomalies in this family will add to our understanding of vascular morphogenesis and related disorders. © 2006 Wiley‐Liss, Inc.
Impaired visual search in drivers with Parkinson's disease
Authors: Uc Ergun Y. , Rizzo Matthew , Anderson Steven W. , Sparks JonDavid , Rodnitzky Robert L. , Dawson Jeffrey D. 
Published: September 2006

AbstractObjectiveTo assess the ability for visual search and recognition of roadside targets and safety errors during a landmark and traffic sign identification task in drivers with Parkinson's disease (PD).MethodsSeventy‐nine drivers with PD and 151neurologically normal older adults underwent a battery of visual, cognitive, and motor tests. The drivers were asked to report sightings of specific landmarks and traffic signs along a four‐lane commercial strip during an experimental drive in an instrumented vehicle.ResultsThe drivers with PD identified significantly fewer landmarks and traffic signs, and they committed more at‐fault safety errors during the task than control subjects, even after adjusting for baseline errors. Within the PD group, the most important predictors of landmark and traffic sign identification rate were performances on Useful Field of View (visual speed of processing and attention) and Complex Figure Test‐Copy (visuospatial abilities). Trail Making Test (B‐A), a measure of cognitive flexibility independent of motor function, was the only independent predictor of at‐fault safety errors in drivers with PD.InterpretationThe cognitive and visual deficits associated with PD resulted in impaired visual search while driving, and the increased cognitive load during this task worsened their driving safety. Ann Neurol 2006
A heterozygous effect for PINK1 mutations in Parkinson's disease?
Authors: Abou‐Sleiman Patrick M. , Muqit Miratul M. K. , McDonald Neil Q. , Yang Yan Xiang , Gandhi Sonia , Healy Daniel G. , Harvey Kirsten , Harvey Robert J. , Deas Emma , Bhatia Kailash , Quinn Niall , Lees Andrew , Latchman David S. , Wood Nicholas W. 
Published: September 2006

AbstractObjectiveTo investigate the significance of PINK1 mutations in sporadic Parkinson's disease (PD).MethodsWe determined the frequency of PINK1 mutations by direct sequencing in a large series of PD patients with apparently sporadic disease (n = 768).ResultsTwelve heterozygous mutations were identified, nine in PD patients and three in control subjects.InterpretationGiven the difficulty in interpreting the pathogenic significance of the heterozygous mutations that have already been reported in parkin and DJ‐1, we first determined the frequency of heterozygous PINK1 mutations in the general population by sequencing a large number of control subjects (n = 768), then subsequently assessed their functional significance by examining their effects on stress‐induced alterations to the mitochondrial membrane potential (ΔΨm). We demonstrate an enrichment of heterozygous mutations in sporadic PD patients compared with matched control subjects (1.2% in PD vs 0.4% in control subjects). Furthermore, we show that they adversely affect ΔΨm in a similar way to the familial G309D mutation. Although it remains difficult to conclusively demonstrate the pathogenicity of heterozygous mutations, the results of this study and the previously reported subclinical nigrostriatal dysfunction in carriers of heterozygous PINK1 mutations suggest the possibility that these heterozygous mutations are a significant risk factor in the development of later onset PD. Ann Neurol 2006
What does it mean to be an author? The intersection of credit, contribution, and collaboration in science
Authors: Birnholtz Jeremy P. 
Published: September 2006

AbstractIn this article, I draw on interview data gathered in the High Energy Physics (HEP) community to address recent problems stemming from collaborative research activity that stretches the boundaries of the traditional scientific authorship model. While authorship historically has been attributed to individuals and small groups, thereby making it relatively easy to tell who made major contributions to the work, recent collaborations have involved hundreds or thousands of individuals. Printing all of these names in the author list on articles can mean difficulties in discerning the nature or extent of individual contributions, which has significant implications for hiring and promotion procedures. This also can make collaborative research less attractive to scientists at the outset of a project. I discuss the issues that physicists are considering as they grapple with what it means to be “an author,” in addition to suggesting that future work in this area draw on the emerging economics literature on “mechanism design” in considering how credit can be attributed in ways that both ensure proper attribution and induce scientists to put forth their best effort.
Information arts and information science: Time to unite?
Authors: Karamuftuoglu Murat 
Published: September 2006

AbstractThis article explicates the common ground between two currently independent fields of inquiry, namely information arts and information science, and suggests a framework that could unite them as a single field of study. The article defines and clarifies the meaning of information art and presents an axiological framework that could be used to judge the value of works of information art. The axiological framework is applied to examples of works of information art to demonstrate its use. The article argues that both information arts and information science could be studied under a common framework; namely, the domain‐analytic or sociocognitive approach. It also is argued that the unification of the two fields could help enhance the meaning and scope of both information science and information arts and therefore be beneficial to both fields.
Article decay in the digital environment: An analysis of usage of OhioLINK by date of publication, employing deep log methods
Authors: Huntington Paul , Nicholas David , Jamali Hamid R. , Tenopir Carol 
Published: September 2006

AbstractThe article presents the early findings of an exploratory deep log analysis of journal usage on OhioLINK, conducted as part of the MaxData project, funded by the U.S. Institute of Museum and Library Services. OhioLINK, the original “Big Deal,” provides a single digital platform of nearly 6,000 full‐text journals for more than 600,000 people; for the purposes of the analysis, the raw logs were obtained from OhioLINK for the period June 2004 to December 2004. During this period approximately 1,215,000 items were viewed on campus in October 2004 and 1,894,000 items viewed off campus between June and December 2004. This article provides an analysis of the age of material that users consulted. From a methodological point of view OhioLINK offered an attractive platform to conduct age of publication usage studies because it is one of the oldest e‐journal libraries and thus offered a relatively long archive and stable platform to conduct the studies. The project sought to determine whether the subject, the search approach adopted, and the type of journal item viewed (contents page, abstract, full‐text article, etc.) was a factor in regard to the age of articles used.
Comparative citation analysis of duplicate or highly related publications
Authors: Knothe Gerhard 
Published: September 2006

AbstractFour cases, illustrated by four examples, of duplicate or highly related publications can be distinguished and are analyzed here using citation data obtained from the Science Citation Index (SCI): (1) publication by different authors in the same journal; (2) the same author(s) publishing in different journals; (3) publication by different authors in different journals; (4) the same author(s) publishing highly related papers simultaneously in the same journal, often as part of a series of papers. Example 1, illustrating case 1, is an occurrence of highly related publications in mechanistic organic chemistry. Example 2, from analytical organic chemistry, contains elements of cases 2 and 3. Example 3, dealing solely with case 3, discusses two time‐delayed publications from analytical biochemistry, which were highlighted by Garfield several times in the past to show how the SCI could be utilized to avoid duplicate publication. Example 4, derived from synthetic organic chemistry (total syntheses of taxol), contains elements of cases 1, 3, and 4 and, to a lesser extent, case 2. The citation records of the highly related or duplicate publications can deviate considerably from the journal impact factors; this was observed in three of the four examples relating to cases 2, 3, and 4. The examples suggest that citation of a paper may depend significantly on the journal in which it is published. As an indicator of this dependence, the journals in which the papers used in the present examples appeared were examined. Other factors such as key words in the paper title may also play a role.
Measuring online information seeking context, Part 1: Background and method
Authors: Kelly Diane 
Published: September 2006

AbstractContext is one of the most important concepts in information seeking and retrieval research. However, the challenges of studying context are great; thus, it is more common for researchers to use context as a post hoc explanatory factor, rather than as a concept that drives inquiry. The purposes of this study were to develop a method for collecting data about information seeking context in natural online environments, and identify which aspects of context should be considered when studying online information seeking. The study is reported in two parts. In this, the first part, the background and method are presented. Results and implications of this research are presented in Part 2 (Kelly, in press). Part 1 discusses previous literature on information seeking context and behavior and situates the current work within this literature. This part further describes the naturalistic, longitudinal research design that was used to examine and measure the online information seeking contexts of users during a 14‐week period. In this design, information seeking context was characterized by a user's self‐identified tasks and topics, and several attributes of these, such as the length of time the user expected to work on a task and the user's familiarity with a topic. At weekly intervals, users evaluated the usefulness of the documents that they viewed, and classified these documents according to their tasks and topics. At the end of the study, users provided feedback about the study method.
A New Protein Engineering Approach Combining Chemistry and Biology, Part I; Site‐Specific Incorporation of 4‐Iodo‐L‐phenylalanine in vitro by Using Misacylated Suppressor tRNAPhe
Authors: Kodama Koichiro , Fukuzawa Seketsu , Sakamoto Kensaku , Nakayama Hiroshi , Kigawa Takanori , Yabuki Takashi , Matsuda Natsuko , Shirouzu Mikako , Takio Koji , Tachibana Kazuo , Yokoyama Shigeyuki 
Published: September 2006

AbstractAn Escherichia coli suppressor tRNAPhe (tRNAPheCUA) was misacylated with 4‐iodo‐L‐phenylalanine by using the A294G phenylalanyl–tRNA synthetase mutant (G294‐PheRS) from E. coli at a high magnesium‐ion concentration. The preacylated tRNA was added to an E. coli cell‐free system and a Ras protein that contained the 4‐iodo‐L‐phenylalanine residue at a specific target position was synthesized. Site‐specific incorporation of 4‐iodo‐L‐phenylalanine was confirmed by using LC–MS/MS. Free tRNAPheCUA was not aminoacylated by aminoacyl–tRNA synthetases (aaRSs) present in the E. coli cell‐free system. Our approach will find wide application in protein engineering since an aryl iodide tag on proteins can be used for site‐specific functionalization of proteins.
Sequence‐Dependent Binding of Dipeptides by an Artificial Receptor in Water
Authors: Schmuck Carsten , Rupprecht Daniel , Wienand Wolfgang 
Published: September 2006

AbstractAn artificial dipeptide receptor (1) was designed and observed to bind the deprotonated dipeptide Ac‐D‐Ala‐D‐Ala‐OH in buffered water with K = 33 100 m−1, whereas other dipeptides such as Ac‐Gly‐Gly‐OH or Ac‐D‐Val‐D‐Val‐OH were bound less efficiently, by factors of more than 10 (K < 3000 m−1). The efficient binding and the pronounced sequence selectivity are the result of a combination of strong electrostatic contacts and size‐discriminating hydrophobic interactions. To provide such a combination, a guanidiniocarbonylpyrrole cation was attached to a novel cyclotribenzylene‐substituted alanine derivative 5, to provide a hydrophobic bowl‐shaped cavity just large enough to bind a methyl group but not any larger alkyl chains, thus causing the receptor to prefer alanine to valine. We describe the synthesis of 1 and the evaluation of its complexation properties in UV and fluorescence titration studies.
DyNAs: Constitutional Dynamic Nucleic Acid Analogues
Authors: Sreenivasachary Nampally , Hickman David T. , Sarazin Dominique , Lehn Jean‐Marie 
Published: September 2006

AbstractDynamic cationic polymers were generated in aqueous media from functionally complementary monomers bearing nucleobase groups.1H NMR spectroscopy was used to follow the polycondensation reaction of the nucleobase‐appended dihydrazides1and2with the dialdehydesBandC. The reversibility of these polymers was established by proton NMR spectroscopy through exchange of the dihydrazide2with polymer1 B. The polymers1 B,2 B,1 C, and2 Crepresent dynamic biopolymers of nucleic acid type, DyNAs. Electrostatic interaction of these polymers with polyanionic entities, such as polyphosphates, polynucleotides, and polyaspartic acid, was shown to take place. It induces a change in size of the dynamic polymer, as it responds by an increase in degree of polymerization to an increase of the overall anionic charge introduced, that is, to the total electrostatic interaction.
δ‐La(BO2)3 ( δ‐LaB3O6): A New High‐Pressure Modification of Lanthanum meta‐Oxoborate.
Authors: Heymann Gunter , Soltner Theresa , Huppertz Hubert 
Published: September 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Resonance in the Electron‐Doped High‐Transition‐Temperature Superconductor Pr0.88LaCe0.12CuO4‐δ.
Authors: Wilson Stephen D. , Dai Pengcheng , Li Shiliang , Chi Songxue , Kang H. J. , Lynn J. W. 
Published: September 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Enthalphies of Formation for the Al—Cu—Ni—Zr Quaternary Alloys Calculated via a Combined Approach of Geometric Model and Miedema Theory.
Authors: Ouyang Yifang , Zhong Xiaping , Du Yong , Feng Yuanping , He Yuehui 
Published: September 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Cheap and Environmentally Benign Electrochemical Energy Storage and Conversion Devices Based on AlI3 Electrolytes.
Authors: Xue Bofei , Fu Zhengwen , Li Hong , Liu Xizhe , Cheng Sunchao , Yao Jia , Li Dongmei , Chen Liquan , Meng Qingbo 
Published: September 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
A Computational Investigation on the Electrochemical Properties of Spinel‐Like LiCoAsO4 as Positive Electrode for Lithium‐Ion Batteries.
Authors: Arroyo‐de Dompablo M. Elena , Amador Ulises 
Published: September 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
α,β‐Unsaturated β‐Silyl Imide Substrates for Catalytic, Enantioselective Conjugate Additions: A Total Synthesis of (+)‐Lactacystin and the Discovery of a New Proteasome Inhibitor.
Authors: Balskus Emily P. , Jacobsen Eric N. 
Published: September 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Highly Enantioselective Aza‐Baylis—Hillman Reaction in a Chiral Reaction Medium.
Authors: Gausepohl Rolf , Buskens Pascal , Kleinen Jochen , Bruckmann Angelika , Lehmann Christian W. , Klankermayer Juergen , Leitner Walter 
Published: September 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Enantioselective Hydrogenation of Acyclic Aromatic N‐Aryl Imines Catalyzed by an Iridium Complex of (S,S)‐1,2‐Bis(tert‐butylmethylphosphino)ethane.
Authors: Imamoto Tsuneo , Iwadate Noriyuki , Yoshida Kazuhiro 
Published: September 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Reaction Behavior of Cumulene in Diels—Alder and Friedel—Crafts Reactions.
Authors: Asakawa Tomohiro , Iinuma Mie , Furuta Takumi , Fujii Satoshi , Kan Toshiyuki , Tanaka Kiyoshi 
Published: September 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Unusual Ambiphilic Carbenoid Equivalent in Amide Cyclopropanation.
Authors: Lin Kuo‐Wei , Yan Shiuan , Hsieh I‐Lin , Yan Tu‐Hsin 
Published: September 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Urea‐Hydrogen Peroxide and Microwave: An Eco‐Friendly Blend for Allylic Oxidation of Alkenes with Catalytic Selenium Dioxide.
Authors: Manktala R. , Dhillon R. S. , Chhabra B. R. 
Published: September 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Iodination of Alcohols Using Triphenylphosphine/Iodine under Solvent‐Free Conditions Using Microwave Irradiation.
Authors: Hajipour Abdol Reza , Falahati Ali Reza , Ruoho Arnold E. 
Published: September 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Highly Regioselective Ring Opening of Epoxides and Aziridines Using (Bromodimethyl)sulfonium Bromide.
Authors: Das Biswanath , Krishnaiah Maddeboina , Venkateswarlu Katta 
Published: September 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.