bluuebunny/crossref_metadata_2025_split huggingface dataset:
DIAGNOSIS AND TREATMENT OF ACUTE ACHILLES TENDON RUPTURE: A COMPREHENSIVE SYSTEMATIC REVIEW
Authors: Rapmartua Ompusunggu Indra Hadi , Yulanda Putra Yosie , Auliya Ahsan 
Published: March 2024

Background: Achilles tendon rupture is a common orthopaedic injury that results in substantial functional limitations throughout a lengthy recovery time. The increasing incidence of Achilles tendon ruptures has been well documented in population-based studies. The delayed treatment of AT ruptures is usually attributable to either poor diagnosis upon injury or patients disregarding their injuries and not presenting to healthcare facilities.
The aim: The aim of this study to show about diagnosis and treatment of acute achilles tendon rupture.
Methods: By the Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) 2020, this study was able to show that it met all of the requirements. This search approach, publications that came out between 2014 and 2024 were taken into account. Several different online reference sources, like Pubmed, SagePub, and Google Scholar were used to do this. It was decided not to take into account review pieces, works that had already been published, or works that were only half done.
Result: In the PubMed database, the results of our search get 17 articles, whereas the results of our search on SagePub get 299 articles, on Google Scholar 6990 articles. Records remove before screening are 5317, so we get 1989 articles fos screening. After we screened based on record exclude, we compiled a total of 12 papers. We included five research that met the criteria.
Conclusion: Multiple evaluative techniques including the addition of diagnostic ultrasound imaging and continuous shear wave elastography (cSWE) to standard clinical tests and measures were used to assess patient-reported symptoms, tendon structure, and tendon functional performance. As treatment recommendations and strategies evolve, decisional conflict may arise when patients with Achilles tendon ruptures are faced with the need to choose a management option. There have been several reviews of management strategies, primarily focused on pairwise comparisons between individual operative and non-operative strategies.
La résistance à la colonialité numérique
Authors: Mayoral-Baños Alejandro 
Published: March 2024

Les technologies numériques sont non seulement colonialistes dans leurs pratiques, mais le sont aussi dans leur création et leur conception. Des propositions provenant de toutes les régions et de toutes les écoles politiques ont été mises en œuvre dans le monde entier pour contrecarrer les effets de la colonialité numérique (par exemple, les grandes sociétés technologiques en Chine, le coup de pouce des organisations internationales pour mettre fin aux inégalités sociales dans le monde au moyen de la numérisation, le rejet des technologies numériques, entre autres), mais on note encore une absence de manières décolonisées et autochtones de créer les technologies numériques.
Ce court article, basé sur ma recherche doctorale, a donc pour but de formuler des principes de conception des technologies numériques décolonisatrices par le récit de la mise sur pied de la plateforme Indigenous Friends (Indigenous Friends Platform - IFP) destinée aux jeunes Autochtones citadins de l'Université York, à Tkaronto, au Canada.
Ett gott liv inom planetens gränser är möjligt. Två böcker pekar på lösningar
Authors: Rådö Göran 
Published: March 2024

För att bidra till att sprida nödvändig kunskap har Greta Thunberg i Klimatboken samlat texter från ett hundratal forskare, experter, aktivister och författare som belyser klimat- , ekologi - och hållbarhetskrisen ur ett helhetsperspektiv. I närmare 20 egna kommentarer tryckta på papper i avvikande färg formulerar hon egna slutsatser och uppmaningar med rubriker som " Vi måste göra något som verkar omöjligt " och " Hopp är något vi måste förtjäna". Boken är på 464 sidor och har givits ut samtidigt i en rad olika länder inför klimattoppmötet i Egypten i november 2022.
Dubbelt exceptionella – att både vara särbegåvad och funktionsnedsatt
Authors: Haglund Bo J.A. 
Published: March 2024

De senaste veckorna har media rapporterat om Den Autistiska Josef, 7 år; en ofrivillig huvudperson i en ovanlig rättegång (1). Det handlar om att hjälp och stöd för autistiska barn i förskolan måste ges på basen av den kunskap som forskningen idag föreslår till autism och specifikt med hänsyn till de funktionshinder som Josef har. Det här vill inte Österåkers kommun ställa upp på utan erbjuder egenutvecklat metodstöd för autism. Föräldrarna menar då att Josef diskriminerats och inte fått det stöd han har rätt till enligt skollagen (1).Det här reser för mig frågor om hur stöd till personer med olika funktionsnedsättningar som adhd och inom autismspektrat ser ut idag.
Andlighet och juridik – inga oförenliga storheter
Authors: Westerhäll Lotta Vahlne 
Published: March 2024

Juridik är läran om rättsreglernas tolkning och tillämpning. Rätten består av ett flertal rättskällor, såsom statuter, rättspraxis, förarbeten, doktrin och i vissa fall även sedvänja. Med ett gemensamt namn brukar de olika reglerna kallas normer. Normerna kräver efterföljd. I den medicinska rätten finns regler om medicinsk vård och behandling. Utförarna av vården ska vid påföljd utföra vården på visst sätt.
Andlighet har med relationen till det egna jaget, andra människor, naturen och högre makter att göra. Andlig vård betecknar arbetet som olika trossamfund utför på sjukhusen genom särskilda tjänster. Genom själavård, riter, stödsamtal till människor i kris fyller de olika trossamfundens representanter ett behov som vårdpersonalen inte alltid kan tillmötesgå. Den andliga vården blir därför ett komplement till de olika professionernas arbete inom sjukvården.
Andlighet och juridik utgör inga oförenliga storheter. Den andliga vården är tämligen omgärdad av rättsliga regler och därmed integrerad i juridiken. Här kommer att ges åtskilliga exempel på detta i syfte att påvisa kopplingen mellan juridik och andlighet.
Varför behövs mer idéburen välfärd? Allmänmänskliga behov framför fjärrstyrda kontrollbehov
Authors: Engman-Broadley Victoria 
Published: March 2024

Svensk välfärd står inför en omvälvande tid och behovet av innovation och omvärdering av systemet är större än någonsin. Vi behöver ifrågasätta gamla antaganden och söka nya lösningar. Speglar dagens grundantaganden som styr det svenska välfärdssystemet verkligen, på ett relevant sätt, verklighetens behov?
Det är dags att utmana New Public Management (NPM), denna styrmodell som med sitt fokus på kontroll, ekonomisering och mätbarhet tycks omöjlig att förena med både humanism och, i det långa loppet – även effektivitet. Det krävs ett paradigmskifte som problematiserar de utvärderingssystem som direkt eller indirekt styr den svenska välfärden.
Nu är det dags att ta nästa steg: låt tvärvetenskaplig och praktiknära forskning visa vilken leverans av tjänst som faktiskt är efterfrågad - när och hur denna möter dessa behov. Identifiera vad som fungerar och säkerställ att denna kunskap återspeglas i de offentliga inköpen av välfärdstjänster. Då öppnas möjligheter för de idéburna aktörerna att bidra med de unika värden som ligger till grund för deras existens. Då kan vi också synliggöra vilka värden som riskerar att gå förlorade i dagens kontroll- och mätstyrda välfärdssystem.
Ultimatumi i presidentit Bill Clinton dhe përgatitjet për intervenimin ushtarak në Kosovë
Authors: Hadri Arbër 
Published: March 2024

Punimi shkencor “Ultimatumi i presidentit Bill Clinton dhe përgatitjet për intervenimin ushtarak në Kosovë (shtator-tetor 1998)”, trajton një temë shumë të rëndësishme për historinë më të re të Kosovës, përfshirjen e Shteteve të Bashkuara në zgjidhjen e çështjes së Kosovës dhe
ecurinë e vendimit për intervenim ushtarak. Kjo temë dhe veçoritë e saja, nuk janë trajtuar më parë në historiografinë shqiptare. Me këtë rast synojmë që të paraqesim rezultate të reja historiografike, të mbështetura në dokumente burimore të institucionit më të lartë amerikan për politikë të jashtme dhe siguri kombëtare, “Këshillit të Sigurisë Kombëtare”.
Kosova gjatë Luftës së Dytë Botërore, 1941-1945
Authors: Meta Beqir 
Published: March 2024

Monografia e lartpërmendur përbën një studim të vlefshëm rreth një teme interesante të historisë sonë kombëtare, atë të Kosovës gjatë
Luftës së Dytë Botërore. Autori e ka ndërtuar studimin në bazë të një strukture të mirëmenduar, e cila mundëson paraqitjen e tij mbi baza shkencore, mundëson analizat, përshkrimet dhe krahasimet e burimeve dhe të argumenteve historike. Autori ka shfrytëzuar një gamë të gjerë
studimesh të autorëve shqiptarë e të huaj, dhe veçanërisht një seri koleksionesh dokumentare nga Arkivi Qendror i Shtetit të Shqipërisë (AQSH), Arkivi Historik i Ministrisë për Evropën dhe Punët e Jashtme të Shqipërisë (AMPEJ), Arkivi i Institutit të Historisë në Tiranë (AIH),
Arkivi Qendror i Forcave të Armatosura të Shqipërisë (AQFA); Arkivi i Kosovës (ASHAK), Arkivi i Institutit të Historisë, Prishtinë, si dhe Arkivi
Kombëtar i SHBA-së. Dëshiroj të theksoj se përzgjedhja e kësaj teme ka qenë sa e guximshme aq dhe e vlefshme pasi është synuar që, përmes
analizës dhe përqasjes autentike, të studiohet një periudhë e mbushur me një veprimtari të ngjeshur politike, ushtarake dhe me shumë ngjarje historike. Studiuesi Ademi, në hyrje paraqet qartë lëndën që trajtohet.
Kosova gjatë Luftës së Dytë Botërore, 1941-1945
Authors: Kaceli Ilirjana 
Published: March 2024

Historia e Kosovës gjatë Luftës së Dytë Botërore është një ndër periudhat më të spikatura në historiografinë shqiptare, e cila është trajtuar në mënyrë të pjesshme në artikuj shkencorë dhe informues apo edhe në disa përmbledhje studimore nga historiografia shqiptare dhe ajo e huaj. Ndërsa, po t’u referohemi teksteve të ndryshme shkollore por edhe në tekstet universitare është e trajtuar shumë pak. Ndaj autori me këtë punim sjell një risi, pasi ai është përpjekur dhe ka arritur të realizojë një monografi me vlerë dhe të rëndësishme për shqiptarët kudo që sot ata ndodhen, Ai në punimin e tij ka përfshirë të gjitha ngjarjet e rëndësishme që kanë ndodhur në Kosovën e asaj periudhe. Andaj libri i dr. Haxhi Ademit, “Kosova gjatë Luftës së Dytë Botërore, 1941-1945” e plotëson boshllëkun pasi sjell një punim të mirëfilltë shkencor të bazuar mbi burime të shumta historike.
Monografia që autori
Justifikimi i intervenimit të NATO-s në Kosovë në aspektin e marrëdhënieve ndërkombëtare
Authors: Kaba Hamit 
Published: March 2024

Artikulli merret me politikën e SHBA-së ndaj Kosovës në vitet 1998-1999, periudhë e shkurtër por me rëndësi shumë të madhe për fatin e shqiptarëve të Kosovës. Kjo çështje trajtohet në tri pjesë: përmes një hyrjeje apo begraundi historik që fokusohet në politikën amerikane ndaj Kosovës në vitet 1990- 1998; tek bisedimet për planin e paqes në Konferencën e Rambujesë, të pranuar nga delegacioni i Kosovës e të refuzuar nga delegacioni serb, tek fushata ajrore e NATO-s kundër Jugosllavisë dhe miratimin e rezolutës 1244 nga Këshilli i Sigurimit, me të cilën u detyrua të pajtohej edhe Jugosllavia dhe ngjarjet që e pasuan atë. Në pjesën e fundit me karakter teorik, autori përpiqet t’i japë përgjigje pyetjes, se: “A ishte i legjitimuar sulmi i NATO-s mbi Jugosllavinë e mbetur?”, duke sjellë aq sa lejon kufiri i një artikulli prova
pro dhe kundër tij. Për shkrimin e këtij artikulli janë shfrytëzuar burime të ndryshme, të vjetra e të reja, të autorëve të huaj e shqiptarë, por studimet apo raportet që i janë paraqitur Kongresit Amerikan për këtë çështje nga viti 1999 e deri në vitin 2018, për shkak të vlerave të veçanta që bartin janë përdorur gjerësisht.
Evaluation of the Outcome of Interventions for Thoracic Endometriosis Syndrome at a Tertiary Level Health Institution in Southern Nigeria
Authors: Amadi Christian Emeka , Alegbeleye Justina Omoikhefe 
Published: March 2024

Background: Thoracic Endometriosis Syndrome (TES) is a clinical condition characterized by the presence of endometrial tissue within the thoracic cavity, catamenial pneumothorax, catamenial haemothorax, catamenial haemopneumothorax, catamenial haemoptysis and or endometrial nodular lung mass. The management can be challenging as treatment is fraught with recurrence.
Aim: To evaluate the outcome of interventions for Thoracic Endometriosis Syndrome.
Methods: This was a prospective cross-sectional study of 14 patients with thoracic endometriosis syndrome who were managed at the university of Port Harcourt Teaching Hospital between August 1, 2017, and July 31, 2023. A proforma was used to collect data on socio-demographic characteristics, clinical presentation, type of intervention and evidence of recurrence of chest symptoms and entered into a spread sheet. Data analysis was done with SPSS version 28. Results are presented as frequency tables and percentages.
Results: The age of the patients ranged between 20 and 44 years. Of the 14 patients, 11 (78.6%) were married, and 3 (21.4%) of the patients had established abdominal endometriosis with symptoms of thoracic endometriosis, while 4 (28.6%) had a histologic diagnosis of thoracic endometriosis. Pneumothorax was observed in 9 (64.23%) patients, 3 (21.43%) had haemopneumothorax, 2 (14.29%) with cyclical haemoptysis and haemothorax, and 4 (28.57%) of the patients had thoracic endometriotic nodules, while all the married patients had primary infertility. Twelve (85.7%) of the patients had closed tube thoracostomy drainage (CTTD) with chemical pleurodesis, while 4 (28.6%) had thoracotomy, decortication, bleb, and nodules resection with chemical pleurodesis. All the patients had hormonal therapy using luteinizing hormone-releasing hormone (LHRH) analogues. There was recurrence in 2 (14.3%) of the patients after a one-to-six-year period of follow-up.
Conclusion: The treatment of TES using CTTD with pleurodesis, thoracostomy, decortication, bleb resection and or hormonal therapy with appropriate patient selection is effective as only two cases of recurrences were recorded.
Evaluation of the Effects of Alpha-Tocopherol, Quercetin and their Combination on Ethanol-Induced Pancreatic and Duodenal Mucosal injuries: An Experimental Study
Authors: Akinrinde A. S.  , Ajibade T. O.  
Published: March 2024

Aim: In this study, the effects of alpha-tocopherol (AT), quercetin (QT) or their combination on ethanol-induced pancreatic and duodenal mucosal damage were investigated in rats using morphological and biochemical evaluations.
Study Design: Experimental study.
Place and Duration of Study: University of Ibadan, Ibadan, Nigeria.
Methodology: Ethanol-induced injuries were produced by oral administration of 40% ethanol (0.2 ml/day) for 40 consecutive days, while a control group of rats was served distilled water. Other groups received AT (2.5 mg/kg), QT (50 mg/kg) or their combination with 40% ethanol during the experimental period.
Results: Blood glucose level was significantly (p<0.05) increased in ethanol-treated rats relative to controls. Ethanol administration caused shrinkage of insulin-secreting islets tissues in the pancreas, while lesions such as erosions, loss of villi and severe inflammatory cell infiltrations of the mucosa and sub-mucosa were observed in the duodenum. These changes were accompanied by significant elevation in the levels of hydrogen peroxide (H2O2), malondialdehyde (MDA) and advanced oxidation protein products (AOPP) in the pancreas and duodenum, along with reduced activities of glutathione peroxidase (GPx) and glutathione S-transferase (GST). Treatment of rats with AT, QT, and especially their combination, yielded profound reversal of ethanol-induced effects indicated by restoration of blood glucose to control levels, preservation of pancreatic and duodenal morphology and the inhibition of ethanol-induced oxidative stress.
Conclusion: Overall, dietary supplementation with AT and/or QT could potentially counteract the adverse effects associated with chronic alcohol consumption.
Optimizing Banana Crop Productivity: Effects of Nitrogen Levels and Plant Growth Regulators on Chlorophyll Dynamics in Ney Poovan Cultivar
Authors: Tamilselvi C. , Vijayashanthi V. A. , Preethi T. L. , Sivagamy K. , Sathish G. , Yogameenakshi P. , Banumathi S. 
Published: March 2024

The present study highlights the Effect of different nitrogen levels and plant growth regulators on Total chlorophyll content and chlorophyll stability index of banana cv. Ney Poovan. A field experiment in banana cv. Ney Poovan was conducted with various levels of nitrogen and plant growth regulators at Orchard, Tamil Nadu Agricultural University, Coimbatore. The experiment was laid out in the complete Randomized Block Design with four main plot and eight sub plot treatments which are replicated thrice. Significant differences among the different treatments in growth and physiological parameters was observed. The results reveled that application of various levels of nitrogen and plant growth regulators 200 g N plant-1 (60g + 100g + 40g N plant-1 at 3,5 and 7 MAP respectively + Urea 2% foliar spray + Salicylic acid (SA) 100 ppm @ 3,5 and 7 MAP respectively i.e. M4S5 recorded the highest chlorophyll content (1.40 mg g-1) and chlorophyll stability index (72.58) which was on par with the M3S5 : 200 g N plant-1 (60g + 100g + 40g N plant-1 at 3,5 and 7 MAP respectively)+ Salicylic acid (SA) 100 ppm @ 3,5 and 7 MAP.
Detection of Stress Proteins as Biomarkers of Oxidative Stress
Authors: Agnew Linda L. , Watson Kenneth 
Published: June 2006

AbstractHeat shock or stress proteins are constitutively expressed redox‐sensitive proteins, the synthesis of which is induced in almost all organisms exposed to a range of stressors, including oxidative stress, heat shock, free radicals, UV radiation, and heavy metals. This unit details three methods, with supporting protocols, for their measurement in peripheral blood mononuclear cells, plasma, and serum. These are [35S]methionine protein labeling, immunoblotting, and ELISA.
Wheat Germ Cell‐Free Expression System for Protein Production
Authors: Vinarov Dmitriy A. , Newman Carrie L. Loushin , Tyler Ejan M. , Markley John L. , Shahan Mark N. 
Published: June 2006

AbstractThe Center for Eukaryotic Structural Genomics, in cooperation with Ehime University and CellFree Sciences, has developed a novel wheat germ cell‐free technology for the production of eukaryotic proteins. Protein production and purification are robust and scalable for high‐throughput applications. The protocols have been used to express and purify proteins fromArabidopsis thaliana, human, mouse, rat and zebra fish. This unit describes expression and purification protocols for both small‐scale testing (microgram) and large‐scale production (milligram) of N‐His6‐ and N‐GST‐tagged proteins. The methods described in this unit can be used to produce both unlabeled and labeled proteins required for structure‐based determinations by NMR spectroscopy or X‐ray crystallography.
Analysis of Protein Sumoylation
Authors: Hilgarth Roland S. , Sarge Kevin D. 
Published: June 2006

AbstractThe covalent attachment of small ubiquitin‐like modifier (SUMO) proteins to specific lysine residues of target proteins, a process termed sumoylation, is a recently discovered protein modification that plays an important role in regulating many diverse cellular processes. For this reason there is significant interest in identifying new sumoylated proteins and the lysine residue(s) within these target proteins where SUMO attachment occurs. Such knowledge will allow determination of the functional consequences of sumoylation through mutation of the relevant sequences. This unit describes two different experimental approaches for ascertaining specific protein sumoylation: the first is based on immunoprecipitation of the protein of interest followed by SUMO immunoblotting. The second involves incubation of the protein (either an in vitro translation product or a purified recombinant protein) in a reconstituted in vitro sumoylation enzymatic reaction followed by visualization of sumoylated protein as a higher than normal molecular‐weight band in SDS‐PAGE.
Combinatorial Recombination of Gene Fragments to Construct a Library of Chimeras
Authors: Meyer Michelle M. , Hiraga Kaori , Arnold Frances H. 
Published: June 2006

AbstractRecombination of distantly related and nonrelated genes is difficult using traditional PCR‐based techniques, and truncation‐based methods result in a large proportion of nonviable sequences due to frame shifts, deletions, and insertions. This unit describes a method for creating libraries of chimeras through combinatorial assembly of gene fragments. It allows the experimenter to recombine genes of any identity and to select the sites where recombination takes place. Combinatorial recombination is achieved by generating gene fragments with specific overhangs, or sticky ends. The overhangs permit the fragments to be ligated in the correct order while allowing independent assortment of blocks with identical overhangs. Genes of any identity can be recombined so long as they share 3 to 5 base pairs of identity at the desired recombination sites. Simple adaptations of the method allow incorporation of specific gene fragments.
Newcastle Disease Virus: Propagation, Quantification, and Storage
Authors: McGinnes Lori W. , Pantua Homer , Reitter Julie , Morrison Trudy G. 
Published: June 2006

AbstractNewcastle disease virus (NDV) is a prototype paramyxovirus used to define basic steps in the life cycle of this family of viruses. NDV is also an ideal virus system for elucidating determinants of viral pathogenicity. Some strains of this virus are important agricultural pathogens that cause disease in poultry with a high mortality while other strains are avirulent and used for vaccines. Methods for preparation and titration of virus stocks are essential for all of these purposes. Procedures for growth and purification of NDV stocks in embryonated chicken eggs as well as in tissue culture cells are described. Use of embryonated chicken eggs to grow the virus is the superior method since infectious stocks of all strains of NDV result. Stocks of avirulent NDV prepared in tissue culture are noninfectious. Virus stocks are routinely titered using plaque assays or hemagglutination assays, both of which are described.
Using Viral Vectors to Silence Endogenous Genes
Authors: Caplan Jeffrey , Dinesh‐Kumar S.P. 
Published: June 2006

AbstractVirus‐induced gene silencing (VIGS) is a fast but transient method for knocking down expression of endogenous genes in plants. Replicating plant viruses activate a defense mechanism called post‐transcriptional gene silencing (PTGS), which protects the plant by silencing viral transcripts. VIGS of endogenous genes is accomplished by inserting a gene of interest into a viral vector. When the virus replicates in the plant, PTGS silences both the viral genome and the corresponding endogenous gene. The most robust and widely implemented VIGS system uses tobacco rattle virus (TRV) vectors and N. benthamiana as the plant host. This unit will explain how to introduce TRV‐based VIGS vectors into N. benthamiana plants by two methods: syringe infiltration or the Agrobacterium drench method. Furthermore, it will provide two alternate protocols optimized for VIGS in tomato plants: spray inoculation and vacuum infiltration.