bluuebunny/crossref_metadata_2025_split huggingface dataset:
Correlations between the ICIQ‐UI short form and urodynamic diagnosis
Authors: Rotar Melita , Tršinar Bojan , Kisner Karel , Barbič Matija , Sedlar Aleš , Gruden Jožica , Vodušek David B. 
Published: March 2009

AbstractAimsUrinary incontinence is a common symptom in many diseases as well as in general population. To measure the impact of urinary incontinence (UI) on individual's quality of life the English short form International Consultation on Incontinence questionnaire (ICIQ‐UI Short Form) has been developed, which consists of three scored and one self‐diagnostic question. Our aim was to translate the ICIQ‐UI Short Form into Slovene, re‐validate it, and test the diagnostic value of the questionnaire in determining the type of UI.MethodsICIQ‐UI Short Form was translated into Slovene and re‐validated. In the validation process we included urology and gynecology outpatient clinics attendants, elderly institutionalized patients, and a community sample. One group of patients underwent urodynamic testing and the results were compared to their responses to question six of the ICIQ‐UI Short Form. Both sets of answers were compared using the Kappa (κ) statistics.ResultsThe Slovene version of the ICIQ‐UI Short Form was found to be valid (excellent test–retest reliability, good internal consistency, good responsiveness to change, and reflected well underlying theories). The questionnaire correlated well with urodynamic findings. The perceived cause of leakage (Question 6) was a good indicator of objectively proven cause of incontinence (Kappa value 0.77).ConclusionsWe found that the Slovene version of the ICIQ‐UI Short Form is a valid and reliable questionnaire for assessment of UI. In addition to its ability to assess the impact of UI on individual's quality of life it also has a diagnostic value of the cause of incontinence. Neurourol. Urodyn. 28:501–505, 2009. © 2009 Wiley‐Liss, Inc.
Continent catheterizable vesicostomy in an adult population: Success at high costs
Authors: Van der Aa Frank , Joniau Steven , De Baets Karen , De Ridder Dirk 
Published: March 2009

AbstractAimsTo evaluate the long term outcome, to review the complication ratio and to analyze predicting factors of catheterizable continent vesicostomy in an adult population. To deduct a proper patient counseling policy.MethodsWe identified all patients that underwent a continent vesicostomy between 1998 and 2008. We did not consider patients that underwent orthotopic bladder reconstruction. Patient satisfaction, urinary leakage, catheterization problems were assessed by chart review or interview. Type of primary surgery, revisions (number and type), renal function and complications were assessed by chart review.ResultsThirty‐four patients underwent continent vesicostomy using an ileal segment (Monti or Spiral‐Monti/Casale technique) or the appendix (Mitrofanoff). One patient underwent a detrusor wall flap. Twenty‐one out of 35 patients underwent concomitant bladder augmentation and 2/35 patients bladder neck closure. Mean age at the time of the procedure was 44 years (range 21–80 years). Mean follow up is 60 months (range 6–117 months). Six out of 35 patients undergo surgical excision of the conduit because of untreatable problems. One patient has a permanent indwelling catheter. Two patients voided normal after sacral nerve stimulation. Ten out of 35 patients undergo stoma related revisions. Sixteen out of 35 patients undergo no stoma related revisions. Finally 26/35 patients were continent and had an easy catheterizable stoma.ConclusionsContinent urinary diversion in an adult population is associated with a high complication and revision rate. Although conversion rate to an ileal conduit is appreciable, the majority of patients (26/35) finally achieve full continence and unobstructed access to the bladder. Neurourol. Urodyn. 28:487–491, 2009. © 2009 Wiley‐Liss, Inc.
Intraurethral stimulation for reflex bladder activation depends on stimulation pattern and location
Authors: Bruns Tim M. , Bhadra Narendra , Gustafson Kenneth J. 
Published: March 2009

AbstractAimsReflex bladder excitation has been demonstrated by stimulation of the pudendal nerve and several of its distal branches. However, excitation parameters have not been consistent and the relationship to anatomical locations within the urethra has not been fully investigated. An improved understanding of the lower urinary tract neurophysiology will improve human studies and neuroprosthetic device development.MethodsIntraurethral stimulation was performed in nine cats at near isovolumetric bladder volumes before and/or after spinalization. Bladder excitability profiles were obtained for lower (2 Hz) and higher (33 Hz) frequency stimuli along the urethra between the bladder neck and external meatus.ResultsHigher frequency stimuli were excitable at all urethral locations prior to spinalization but only excitable in the middle and distal urethra after spinalization. Lower frequency stimuli were excitable at proximal and middle locations before spinalization but not excitable at any location after spinalization. In most evaluations, bursting pulse stimulation patterns evoked greater bladder pressures than the dominant continuous frequency (2 or 33 Hz).ConclusionsThese data indicate the potential presence of two distinct pathways for reflex bladder activation within the urethra: a supra‐T10 circuit initiated in the proximal and mid urethra that responds to lower and higher frequency stimuli, and a sacral circuit initiated in the mid and distal urethra that responds to higher frequency stimuli. This work suggests potential anatomical targets and stimulus patterns for clinical evaluations of peripheral nerve‐based neuroprostheses for bladder control. Neurourol. Urodyn. 28:561–566, 2009. © 2009 Wiley‐Liss, Inc.
Different estrogen sensitivity of urogenital tissue from women with and without stress urinary incontinence
Authors: Edwall Lena , Carlström Kjell , Jonasson Aino Fianu 
Published: March 2009

AbstractAimsOral hormone replacement therapy (HRT) based on estradiol‐17β (E2), E2 esters or conjugated equine estrogens gives rise to huge amounts of circulating estrone (E1) as a result of the first liver pass. E1 is an estrogen (ER) receptor agonist but has also been reported to act as a partial E2 antagonist in vitro. Our aim was to investigate the influence of circulating estrogens on estrogen sensitivity of urogenital tissue collagen turnover in patients with stress urinary incontinence (SUI) and in urologically healthy women, with and without HRT, in view of possible effects of E1 as a partial E2 antagonist. MethodsMarkers of collagen turnover, the carboxy‐terminal propeptide of type I procollagen (PICP), the carboxy‐terminal telopeptide of type I collagen (ICTP) and the amino‐terminal propeptide of procollagen III (PIIINP) were assayed in urogenital tissue homogenates and E1 and E2 were analyzed in serum from 54 patients with SUI and 29 urologically healthy women. ResultsIn the total control group only a significant positive correlation was found between E2 and T‐PICP. Lowering the upper serum E1 limit resulted in significant positive correlations also between E2 and T‐PIIINP and finally also between E2 and T‐ICTP. This pattern was found also in subgroups of post‐ and premenopausal controls. No association between serum E2 and collagen turnover markers and no effects of lowering the upper serum E1 limit was found in the total and postmenopausal SUI patients, while the correlation pattern in premenopausal SUI patients showed some resemblance to that in the controls. ConclusionAt physiological E1 levels E2 increases collagen turnover in urogenital tissue in urologically healthy women but not in women with SUI in general; however, there was a certain effect of E2 in premenopausal but not in postmenopausal SUI patients. Urogenital tissue in SUI patients and in urologically healthy women may differ in estrogen sensitivty and in SUI patients this difference may be related to menopause. Circulating E1, which is present in huge amounts during oral HRT, may act as an estrogen receptor agonist as well as a partial E2 antagonist also in humans in vivo. Neurourol. Urodyn. 28:516–520, 2009. © 2009 Wiley‐Liss, Inc.
Lower urinary tract dysfunction in children with cerebral palsy
Authors: Silva José Ailton Fernandes , Alvares Ronaldo Alvarenga , Barboza André Luis , Monteiro Raphael Temporão Maciel 
Published: March 2009

AbstractAimsThe focus of this study was to evaluate urodynamic findings and possible renal damage in children with cerebral palsy and urinary symptoms.MethodsChildren with cerebral palsy and lower urinary tract symptoms were studied. Patients were submitted to urodynamic evaluation, urine examination, measurement of serum creatinine, and renal and urinary tract ultrasonography. Voiding cystourethrography was performed on patients with urinary tract infections.ResultsThirty‐seven children were investigated, including 21 females and 16 males. The mean age was 7 years and 8 months [SD of 4 years 6 months], with a range from 1 to 17‐year‐old. The symptoms that led to evaluation were urinary infections in 21 56.7% cases, incontinence in 15 (40.5%) cases, increased voiding frequency in six (16%) cases, enuresis in five (13.5%) cases, and hesitancy and urgency in two (5.4%) cases each. The urodynamic findings involved reduced bladder capacity in 20 (54%) cases, with mean cystometric capacity of 168.0 ± 122.2 ml. Detrusor overactivity was observed in 13 (35.1%) cases, with mean of 67.9 ± 34.6 cmH2O. The range of the residual volume was 17.5 ± 33.5 ml, which was increased in five (13.5%) cases. Low bladder compliance was seen in four (10.8%) patients, mean bladder compliance of 22.2 ± 12.2 ml/cmH2O. No hydronephrosis or reflux was observed.ConclusionAlmost one‐third of the patients with cerebral palsy and urinary symptoms presented with normal urodynamic findings. The most frequent findings were reduced bladder capacity, detrusor overactivity, and increased post‐void residual. No urinary tract complications were observed. Neurourol. Urodynam. 28:959–963, 2009. © 2009 Wiley‐Liss, Inc.
Slice‐selective FID acquisition, localized by outer volume suppression (FIDLOVS) for 1H‐MRSI of the human brain at 7 T with minimal signal loss
Authors: Henning Anke , Fuchs Alexander , Murdoch James B. , Boesiger Peter 
Published: March 2009

AbstractIn comparison to 1.5 and 3 T, MR spectroscopic imaging at 7 T benefits from signal‐to‐noise ratio (SNR) gain and increased spectral resolution and should enable mapping of a large number of metabolites at high spatial resolutions. However, to take full advantage of the ultra‐high field strength, severe technical challenges, e.g. related to very short T2 relaxation times and strict limitations on the maximum achievable B1 field strength, have to be resolved. The latter results in a considerable decrease in bandwidth for conventional amplitude modulated radio frequency pulses (RF‐pulses) and thus to an undesirably large chemical‐shift displacement artefact. Frequency‐modulated RF‐pulses can overcome this problem; but to achieve a sufficient bandwidth, long pulse durations are required that lead to undesirably long echo‐times in the presence of short T2 relaxation times. In this work, a new magnetic resonance spectroscopic imaging (MRSI) localization scheme (free induction decay acquisition localized by outer volume suppression, FIDLOVS) is introduced that enables MRSI data acquisition with minimal SNR loss due to T2 relaxation and thus for the first time mapping of an extended neurochemical profile in the human brain at 7 T. To overcome the contradictory problems of short T2 relaxation times and long pulse durations, the free induction decay (FID) is directly acquired after slice‐selective excitation. Localization in the second and third dimension and skull lipid suppression are based on a T1‐ and B1‐insensitive outer volume suppression (OVS) sequence. Broadband frequency‐modulated excitation and saturation pulses enable a minimization of the chemical‐shift displacement artefact in the presence of strict limits on the maximum B1 field strength. The variable power RF pulses with optimized relaxation delays (VAPOR) water suppression scheme, which is interleaved with OVS pulses, eliminates modulation side bands and strong baseline distortions. Third order shimming is based on the accelerated projection‐based automatic shimming routine (FASTERMAP) algorithm. The striking SNR and spectral resolution enable unambiguous quantification and mapping of 12 metabolites including glutamate (Glu), glutamine (Gln), N‐acetyl‐aspartatyl‐glutamate (NAAG), γ‐aminobutyric acid (GABA) and glutathione (GSH). The high SNR is also the basis for highly spatially resolved metabolite mapping. Copyright © 2009 John Wiley & Sons, Ltd.
A dual echo approach to removing motion artefacts in fMRI time series
Authors: Buur Pieter F. , Poser Benedikt A. , Norris David G. 
Published: March 2009

AbstractIn fMRI, subject motion can severely affect data quality. This is a particular problem when movement is correlated with the experimental paradigm as this potentially causes artefactual activation. A method is presented that uses linear regression, to utilise the time course of an image acquired at very short echo time (TE) as a voxel‐wise regressor for a second image in the same echo train, that is acquired with high BOLD sensitivity. The value of this approach is demonstrated using task‐locked motion combined with visual stimulation. Results obtained at both 1.5 and 3 T show improvements in functional activation maps for individual subjects. The method is straightforward to implement, does not require extra scan time and can easily be embedded in a multi‐echo acquisition framework. Copyright © 2009 John Wiley & Sons, Ltd.
Detecting colorectal cancer by 1H magnetic resonance spectroscopy of fecal extracts
Authors: Bezabeh T. , Somorjai R. , Dolenko B. , Bryskina N. , Levin B. , Bernstein C. N. , Jeyarajah E. , Steinhart A. H. , Rubin D. T. , Smith I. C. P. 
Published: March 2009

AbstractColorectal cancer is one of the most common cancers in the western world. Its early detection has been found to improve the prognosis of the patient, providing a wide window of opportunity for successful therapeutic interventions. However, current diagnostic techniques all have some limitations; there is a need to develop a better technique for routine screening purposes. We present a new methodology based on magnetic resonance spectroscopy of fecal extracts for the non‐invasive detection of colorectal cancer. Five hundred twenty‐three human subjects (412 with no colonic neoplasia and 111 with colorectal cancer, who were scheduled for colonoscopy or surgery) were recruited to donate a single sample of stool. One‐dimensional 1H magnetic resonance spectroscopy (MRS) experiments were performed on the supernatant of aqueous dispersions of the stool samples. Using a statistical classification strategy, several multivariate classifiers were developed. Applying the preprocessing, feature selection and classifier development stages of the Statistical Classification Strategy led to ∼87% average balanced sensitivity and specificity for both training and monitoring sets, improving to ∼92% when only crisp results, i.e. class assignment probabilities ≥75%, are considered. These results indicate that 1H magnetic resonance spectroscopy of human fecal extracts, combined with appropriate data analysis methodology, has the potential to detect colorectal neoplasia accurately and reliably, and could be a useful addition to the current screening tools. Copyright © 2009 John Wiley & Sons, Ltd.
Fictitious domain method with penalty for an incompressible fluid
Authors: Zhu Jingtao , Ma Yichen 
Published: March 2009

AbstractFictitious domain method shows great advantages when handling problems with complex and constantly varying domains. In this article, we propose an algorithm which extends the fictitious domain method by introducing penalties. Test results with the numerical examples of backward facing step problem and the flow around steady and dynamic cylinder problem show that the algorithm we propose is highly efficient for solving incompressible fluid problems. © 2009 Wiley Periodicals, Inc. Numer Methods Partial Differential Eq, 2010
Numerical solution of hyperbolic telegraph equation using the Chebyshev tau method
Authors: Saadatmandi Abbas , Dehghan Mehdi 
Published: March 2009

AbstractIn this article we propose a numerical scheme to solve the one‐dimensional hyperbolic telegraph equation. The method consists of expanding the required approximate solution as the elements of shifted Chebyshev polynomials. Using the operational matrices of integral and derivative, we reduce the problem to a set of linear algebraic equations. Some numerical examples are included to demonstrate the validity and applicability of the technique. The method is easy to implement and produces very accurate results. © 2009 Wiley Periodicals, Inc. Numer Methods Partial Differential Eq, 2010
Numerical experiments on optimal shape parameters for radial basis functions
Authors: Roque C. M. C. , Ferreira A. J. M. 
Published: March 2009

AbstractA numerical investigation on a technique for choosing an optimal shape parameter is proposed. Radial basis functions (RBFs) and their derivatives are used as interpolants in the asymmetric collocation radial basis method, for solving systems of partial differential equations. The shape parameter c in RBFs plays a major role in obtaining high quality solutions for boundary value problems. As c is a user defined value, inexperienced users may compromise the quality of the solution, often a problem of this meshless method. Here we propose a statistical technique to choose the shape parameter in radial basis functions. We use a cross‐validation technique suggested by Rippa Adv Comput Math 11 (1999), 193–210 for interpolation problems to find a cost function Cost(c) that ideally has the same behavior as an error function. If that is the case, the parameter c that minimizes the cost function will be an optimal shape parameter, in the sense that it minimizes the error function. The form of the cost and error functions are analized for several examples, and for most cases the two functions have a similar behavior. The technique produced very accurate results, even with a small number of points and irregular grids. © 2009 Wiley Periodicals, Inc. Numer Methods Partial Differential Eq, 2010
Development of the ways of helping questionnaire: A measure of preferred coping strategies for older African American cancer survivors
Authors: Hamilton Jill B. , Stewart Barbara J. , Crandell Jamie L. , Lynn Mary R. 
Published: March 2009

AbstractAlthough researchers have identified beneficial coping strategies for cancer patients, existing coping measures do not capture the preferred coping strategies of older African American cancer survivors. A new measure, the Ways of Helping Questionnaire (WHQ), was evaluated with 385 African American cancer survivors. Validity evidence from factor analysis resulted in 10 WHQ subscales (Others There for Me, Physical and Treatment Care Needs, Help from God, Church Family Support, Helping Others, Being Strong for Others, Encouraging My Healthy Behaviors, Others Distract Me, Learning about Cancer, and Distracting Myself). Reliability evidence was generally strong. Evidence regarding hypothesized relationships with measures of well‐being and another coping measure was mixed. The WHQ's content coverage makes it especially relevant for older African American cancer survivors. © 2009 Wiley Periodicals, Inc. Res Nurs Health 32:243–259, 2009
A sacral anomaly from the Quaker Cemetery, Kingston‐upon‐Thames, England
Authors: Pitre Mindy C. , Lovell Nancy C. 
Published: March 2009

AbstractA rare defect of the sacrum was observed in the skeleton of an adult female from the Quaker Cemetery (1663–1814 CE) in Kingston‐upon‐Thames, England. This is an isolated finding in the skeletal collection and no other elements in this individual were similarly affected. After eliminating post‐depositional damage and skeletal asymmetry, a differential diagnosis resulted in the consideration of two conditions: hemivertebra and sacral agenesis, both of which are rare developmental defects that originate during foetal growth. Although the defect is interesting from an embryological, genetic and palaeopathological perspective, it would have resulted in few clinical symptoms for the individual. This case adds to the limited knowledge of the morphological variability of the sacrum, and will aid in future diagnoses of these rare pathological conditions. Copyright © 2009 John Wiley & Sons, Ltd.
Characterisation and identification of isomeric dibenzocyclooctadiene lignans from Schisandra Chinensis by high‐performance liquid chromatography combined with electrospray ionisation tandem mass spectrometry
Authors: Shi Peiying , He Qing , Zhang Yufeng , Qu Haibin , Cheng Yiyu 
Published: March 2009

AbstractIntroductionDibenzocyclooctadiene lignans are bioactive constituents in Schisandra chinensis (Turcz.) Baill. They are often present as isomers and this makes structural discrimination difficult.ObjectiveTo develop a rapid approach towards the characterisation and identification of isomeric dibenzocyclooctadiene lignans from S. chinensis using HPLC‐PAD‐ESI‐MSn.MethodologyThe fragmentation behaviours of seven dibenzocyclooctadiene lignans from S. chinensis were studied using ion trap mass spectrometry with positive electrospray ionisation and loop injection. The fragmentation patterns of angeloylgomisin H, tigloylgomisin H, benzoylgomisin H and gomisin D were supported by high‐resolution mass spectrometric analysis of some characteristic ions using a time‐of‐flight mass spectrometer. Combined with high‐performance liquid chromatography and photodiode array detection, the established approach to the structural identification of dibenzocyclooctadiene lignans by ion trap mass spectrometry was applied to the analysis of extracts of S. chinensis.ResultsAccording to the HPLC retention behaviour, the diagnostic UV spectra and the molecular structural information provided by multistage mass spectrometry spectra and the literature, a total of 25 dibenzocyclooctadiene lignans, including seven groups of lignan isomers, were identified or tentatively characterised in S. chinensis rapidly. One of these was reported as a constituent of S. chinensis for the first time.ConclusionThis study has shown that HPLC‐PAD‐ESI‐MSn may be used as an effective and rapid method for the characterisation and identification of isomeric dibenzocyclooctadiene lignans from S. chinensis. Copyright © 2009 John Wiley & Sons, Ltd.
Stability studies of alprazolam tablets: effects of chemical interactions with some excipients in pharmaceutical solid preparations
Authors: Castañeda Beatriz , Ortiz‐Cala William , Gallardo‐Cabrera Cecilia , Nudelman Norma Sbarbati 
Published: March 2009

AbstractAn HPLC method was developed to determine the stability of alprazolam (AL) as a pure drug and in monodrug pharmaceutical tablets. The main degradation product of AL tablets was isolated and fully characterized as triazolaminoquinoleine (TAQ). For a quantitative evaluation of the excipient effects in the pharmaceutical formulations, a 2k fractionated factorial design was applied in the preparation of the different samples. The kinetic of degradation of AL in each formulation was followed by UV spectrophotometry. It was found that excipients like CMC and magnesium stearate favour degradation, while the rate of the reaction is decreased when lactose and starch were used as excipients. A mechanism for the interactions of AL with some excipients is postulated that explains the observed results. Copyright © 2009 John Wiley & Sons, Ltd.