bluuebunny/crossref_metadata_2025_split huggingface dataset:
Computerized tomography of the glottis after intracordal autoiogous fat injection
Authors: Laccourreye Ollivier , Bély Natacha , Crevier-Buchman Lise , Brasnu Daniel , Halimi Philippe 
Published: November 2007

AbstractAccording to the committee on speech, voice, and swallowing disorders of the American Academy of Otolaryngology – Head and Neck Surgery, various surgical methods such as laryngeal framework surgery, laryngeal re-innervation, and injection laryngoplasty might be used to palliate inferior laryngeal nerve paralysis. In the present case report we document the survival and exact location of the boluses of autoiogous fat in one patient in whom this material was used for injection laryngoplasty.
A systematic approach to the interpretation of computed tomography scans prior to endoscopic sinus surgery
Authors: Mason J. D. T. , Jones N. S. , Hughes R. J. , Holland I. M. 
Published: November 2007

AbstractComputed tomography (CT) provides an excellent map for the sinus surgeon aswell as providing information about the extent of disease and the presence of bony destruction. Surgeons need to be aware of the anatomical configuration of the sinuses and the presence of any structural changes such as a dehiscent lamina papyracea, asymmetric skull base, low level of posterior skull base or an Onodi cell, which place the patient at increased risk. Described here is a six-step guide to help the sinus surgeon avoid missing any of the radiologically important features.
Selective lateral neck dissection for laryngeal cancer with limited metastatic disease: is it indicated?
Authors: Ferlito Alfio , Rinaldo Alessandra 
Published: November 2007

AbstractThe most important prognostic factor in cancer of the larynx is the presence of cervical metastatic disease, which is the most common type of recurrence in such patients. Because micrometastases cannot be detected pre-operatively at present, selective lateral neck dissection is increasingly recommended as the standard treatment for patients with a clinically negative neck in order to reduce the recurrence rate. In cases of N+ disease, selective lateral neck dissection can be as valid as modified radical neck dissection, providing patients have only limited, occult metastatic disease.
Changes in the clinical presentation of chronic otitis media from the 1970s to the 1990s
Authors: Vartiainen Eero 
Published: November 2007

AbstractClinical features of 1123 patients with chronic otitis media referred to a Finnish university hospital for surgical treatment over a 20-year period were analyzed. The number of patients declined by 48 per cent from the period 1976–1985 to 1986–1995. The decline was evident in all age groups but the proportion of children increased significantly from 14 per cent in 1976–1985 to 20 per cent in 1986–1995. A male predominance was noted with the exception of patients with sequelae of otitis in whom the sex distribution was equal. In cholesteatomatous ears, no significant change occurred in the type or size of cholesteatomas or in the incidence of ossicular destruction. Likewise, no significant change was noted in the size of perforations or in the incidence of ossicular destruction in patients with dry eardrum perforations. However, hearing levels of patients treated 1976–1985 were significantly worse than those of patients 1986–1995. Severe complications caused by the disease were rare during both periods.
A clinic for the rapid processing of patients with neck masses
Authors: Vowles Richard H. , Ghiacy Sabour , Jefferis Anthony F. 
Published: November 2007

AbstractNeck masses are common and may have serious underlying pathology. There is much anxiety and confusion in primary care as to which hospital department will provide the patient with the best service and the swiftest diagnosis. A clinic was set up at Wexham Park hospital to enable patients with neck masses to be seen early, and to undergo a one-stop specialist evaluation, ultrasound scan and fine needle aspiration biopsy. The clinic has yielded a wide variety of benign and malignant pathology. The first 100 patients are discussed and evaluated.
Mucocele mimicking a Warthin's tumour recurrence
Authors: Rejali D. , Simo R. , Small M. 
Published: November 2007

AbstractWe report an unusual case of an extravasation mucocele complicating superficial parotidectomy. The tumour excised was a Warthin's tumour. Three months following theprimary surgery a cystic lesion appeared in the parotid bed. It was initially thought to represent a recurrence. The area was re-explored and a mucocele excised. The pathogenesisof mucoceles and the difficulties encountered when dealing with parotid tumour recurrenceare discussed.
Pseudoaneurysm of subclavian artery – atypical presentation
Authors: Gupta A. K. , Gupta P. C. , Abrol Raman , Mann S. B. S. 
Published: November 2007

AbstractWe present a rare case of pseudoaneurysm of right subclavian artery who presented with supraclavicular mass. Injury of the subclavian artery causing pseudoaneurysm is a serious surgical emergency and a surgical intervention is indicated.
Mechanisms in noise-induced permanent hearing loss: an evoked otoacoustic emission and auditory brainstem response study
Authors: Xu Zheng-Min , Vinck Bart , De Vel Eddy , van Cauwenberge Paul 
Published: November 2007

AbstractIn this study 22 patients (44 ears) with noise-induced permanent hearing loss were audiologically evaluated using transient-evoked otoacoustic emissions (TEOAE) and auditory brain-stem response (ABR). Twenty-one normal subjects (42 ears) without exposure to occupational noise were used as controls. Based upon the hearing loss at 4, 3, 2 and 1 kHz on the pure-tone audiogram, they were classified into four groups. In group 1 (eight ears), emissions were present in all ears but their TEOAE-noise level and their reproducibility (percentage) proved to be weak. The auditory brain-stem response (ABR) indicated that the I/V amplitude ratio, the latency values of wave V and the I–V intervals fell within the normal range in all ears. In Group 2 (14 ears), 40 per cent had no emissions, whereas the remaining ears showed weak emissions. The ABR revealed that in all ears the I/V amplitude ratio became small while wave V peak latency as well as I–V intervals were within the normal range. In Group 3 (10 ears), emissions were absent in 50 per cent, while in the other ears the emissions were very weak. The ABR revealed that the I/V amplitude ratio, which could be calculated in the 60 per cent in which wave I was present, was smaller than in Group 2. Wave V latency as well as I–V intervals were within the normal range. In Group 4 (12 ears), none of the ears showed emissions. The ABR indicated that the I/V amplitude ratio was much smaller when wave I was present (27 per cent) as well as I–V interval values being within the normal range. Wave V absolute latency value (δV index) indicated a positive index in 17 per cent of this group (two ears) when wave I was absent. In the present study a dynamic process from cochlear outer hair cells to cochlear neurons was seen, correlating with an increasing hearing loss.
Bacteriology of chronic purulent secretions in chronic rhinosinusitis
Authors: Klossek Jean-Michel , Dubreuil Luc , Richet Hervé , Richet Béatrice , Beutter Patrice 
Published: November 2007

AbstractThe aim of this work was to study the bacterial flora of purulent secretions during chronic rhinosinusitis. We studied a total of 533 patients divided into two groups. The control population consisted of 139 adults (> 16 years) of both sexes seen in the community or hospitalized for less than 72 hours for non-rhinological conditions. The rhinosinusitis group consisted of 394 patients referred to the ENT clinic with chronic rhinosinusitis. All the patients with rhinosinusitis had had a post-nasal discharge for at least three months, associated with purulent or mucopurulent secretions originating from the involved sinus cavity. All samples were obtained endonasally under endoscopic guidance from the sinus ostium or from the sinus cavity during surgery. Cultures were positive in 81.3 per cent of the control subjects and 83.1 per cent of the patients with rhinosinusitis.Corynebacteria, coagulase-negative staphylococci, propionibacteria and peptostreptococci were the main commensal organisms, whileHaemophilus influenzae, streptococci,Streptococcus pneumoniae, Prevotellaspp andFusobacteriumspp were probable causative pathogens. Anaerobes were isolated from approximately 25 per cent of the patients in the rhinosinusitis group. Betalactamase producers represented 27.5 per cent ofH. influenzaeand 28 per cent ofPrevotellaspp isolates. Diminished susceptibility to penicillin was found in 13 per cent ofS. pneumoniaeisolates. The amoxycillin-clavulanate combination was the most active oral antibiotic tested against the pathogenic species in vitro.
Thyroplasty for functional rehabilitation of the incompetent larynx
Authors: Abdel-Aziz M. F. , Gad El-Hak N. A. , Carding P. N. 
Published: November 2007

AbstractType I thyroplasty was performed in 12 patients with unilateral paralysis of the vocal fold. Subjective as well as objective improvement in vocal performance was reported in 11 patients. Aspiration was improved in six out of eight patients. Effort closure was evaluated by the ability of the patient to voluntarily raise his intra-abdominal pressure during Valsalva's manoeuvre. A comparison of pre- and post-thyroplasty measures, showed a statistically significant improvement in the efficacy of effort glottic closure (p < 0.05), indicating a better physical performance. We had one case of wound sepsis and another case of implant extrusion.
Infectious mononucleosis and bilateral peritonsillar abscesses resulting in airway obstruction
Authors: Burstin P. P. , Marshall C. L. 
Published: November 2007

AbstractUpper airway obstruction is an uncommon but recognized complication of infectious mononucleosis. The management depends upon the degree of airway compromise. In the case described, severe airway obstruction was treated by securing the airway with awake fibre-optic endoscopic intubation and then proceeding to tonsillectomy. Bilateral inferiorly loculated quinsies were encountered unexpectedly and drained. This is the first report of ‘bilateral’ quinsies, associated with infectious mononucleosis and severe airway obstruction. The association, pathogenesis and significance of this finding are also discussed.
A history of The Royal National Throat, Nose and Ear Hospital 1874–1982
Authors: Gould Glenice 
Published: November 2007

PrefaceThis history of the Royal National Throat, Nose and Ear Hospital at Gray's Inn Road formed the core of a thesis submitted to the Open University for a Doctorate of Philosophy and is not an official history. I was encouraged to give it wider circulation particularly by Sir Donald Harrison and Mr Edward Donald. The Special Trustees of the Hospital have most generously sponsored this supplement which I hope will serve to provide some interest to those who have worked at Gray's Inn Road. I must begin with an apology as it does not attempt to record the achievements of all the staff at the RNTNE and many eminent contributors to the success of the Hospital have been omitted either through my own ignorance or through lack of space to cover all areas of the Hospital's development. I have been fortunate in obtaining both written and oral historical memoirs from retired doctors, nurses, administrators and technicians who worked for many years at Gray' Inn Road. I would like particularly to thank Peter Zwarts, librarian of the Institute of Laryngology and Otology, and the librarians at the Wellcome Institute for the History of Medicine and the Guildhall. I would like to thank Andrew Gardner of the ILO for a number of the illustrations. In particular I would like to thank my OU supervisor, Dr Noel Coley, for his patience and encouragement.
Secondary tonsillectomy haemorrhage and non-steroidal anti-inflammatory drugs
Authors: Smith I. , Wilde A. 
Published: November 2007

AbstractModern non-steroidal anti-inflammatory drugs (NSAIDs), are now widely accepted analgesics for posttonsillectomy patients, but their effect on secondary haemorrhage has not been fully evaluated.This study attempts to evalute the influence of NSAIDs on the secondary haemorrhage rate, and also whether mode of dissection is an important factor.The records of 557 consecutive patients undergoing tonsillectomy were studied to determine if there was a relationship between the secondary haemorrhage rate and discharge prescription of NSAIDs.There was an overall secondary haemorrhage rate of 5.2 per cent (29) and a significantly increased secondary haemorrhage rate in those taking regular NSAIDs, 11 per cent, compared to those not taking NSAIDs, 1.47 per cent, ().There was a higher rate of secondary haemorrhages with bipolar dissection than with standard dissection for both those taking and not taking NSAIDs (13 per cent vs seven per cent and 2.75 per cent vs 0.87 per cent) however this was not statistically significant ( and ). Both bipolar dissection and standard dissection individually showed very significant increases in secondary haemorrhage rate when on regular NSAIDs ( and ).Although NSAIDs are very good analgesics, they may cause an increased secondary haemorrhage rate, and should be prescribed at discharge prescription with caution.
Effects of capsaicin pre-treatment in experimentally-induced secretory otitis media
Authors: Başak Sema , Türkütanit Serap , Sarierler Murat , Metin Kubilay K. 
Published: November 2007

AbstractNeurogenic inflammation may play a role in the aetiology of secretory otitis media (SOM). The strongest candidate that initiates the characteristic symptoms of neurogenic inflammation is supposed to be substance P. Capsaicin is a specific antagonist of substance P. The effects of capsaicin on middle ear mucosa have not been studied yet. In an attempt to investigate the effect of pre-treatment with capsaicin on the development of SOM an experimental study was performed. Fourteen Wistar rats were divided into two groups. Seven rats were pre-treated with capsaicin (Group 1) and the others were administered isotonic saline solution (Group 2). Seven days after the third injection rats were operated on and the right tympanal orifice of the Eustachian tube was obstructed. Animals were sacrificed seven days after the operation. Their bullas were excised bilaterally and were studied by light microscopic technique. In Group 1 there was no effusion except for one case. The subepithelial layer was thickened by fibroblast proliferation. Capillary proliferation and some glandular atrophy were observed. In Group 2 the middle ear lumens were filled with effusion. Oedema with dilatation in capillaries and medium-sized vessels of lamina propria was observed as a common feature of the group. Subepithelial fibrosis was found in one case. Capsaicin pre-treatment prevented the formation of effusion in the middle ear lumen in spite of tuba occlusion. The results of this preliminary study lead us to consider that an imbalance in the autonomic innervation of the mucosa of the middle ear may play a role in the aetiology of SOM as in vasomotor rhinitis, and capsaicin may be an alternative in the treatment.
An adequate parameter evaluating the galvanic body sway test: comparison with the caloric test in patients with vestibular schwannomas
Authors: Tsutsumi Takeshi , Komatsuzaki Atsushi 
Published: November 2007

AbstractIt has been reported that the galvanic body sway test does not correlate with the caloric test. We evaluated the galvanic body sway test in patients with vestibular schwannomas using three parameters: the angle of deviation response onset, the maximum value of the deviation response, and the area of deviation. These parameters reflect velocity, position, and locus of the centre of pressure respectively. Among these parameters, only the angle of deviation response onset showed unilateral weakness of the response correlating with the canal paresis value, which indicates that velocity is responsible for conduction in the vestibular nerve. However, the galvanic body sway test is apt to be preferred to the caloric test. This might be attributed to the decreased sensitivity of this test.
Leiomyosarcoma of the larynx
Authors: Yoshizaki Tomokazu , Horikawa Toshiyuki , Nonomura Akitaka , Furukawa Mitsuru 
Published: November 2007

AbstractTumours of smooth muscle origin are extremely rare in the upper aerodigestive tract. Immunohistochemical studies are helpful for accurate diagnosis of leiomyosarcoma. Here, we report a case of well-differentiated laryngeal leiomyosarcoma that showed rapid local growth but no metastasis. Diagnosis and treatment of leiomyosarcoma are discussed.
Acute angle closure glaucoma precipitated by intranasal application of cocaine
Authors: Hari C. K. , Roblin D. G. , Clayton M. I. , Nair R. G. 
Published: November 2007

AbstractWe describe a patient who developed acute angle-closure glaucoma following the application of topical intranasal cocaine. A 46-year-old woman underwent an elective antral washout under general anaesthesia and with local application of 25 per cent cocaine paste to the nasal mucosa. Twenty-four hours post-operatively the patient developed sudden painful blindness which was found to be due to acute glaucoma. Cocaine with its indirect sympathomimetic activity causes mydriasis, that can precipitate acute angle-closure glaucoma in predisposed individuals with a shallow anterior chamber. Although the incidence is rare, otolaryngologists need to be aware of this potential complication.
The influence of pregnancy on sensation of ear problems – ear problems associated with healthy pregnancy
Authors: Tsunoda Koichi , Takahashi Shizue , Takanosawa Minako , Shimoji Yoshitaka 
Published: November 2007

AbstractWe wondered how many women had experienced a sensation of fullness in the ear during pregnancy. To address this question, data were obtained from a group of healthy women who attended the gynaecology clinic in our hospital as pregnancy cases between February 1995 and January 1998 and who volunteered to participate in our study. A control group was drawn from healthy female co-medical staff members of our hospital who had never been pregnant. The data used for comparing the two groups were taken from a questionnaire about ear problems that was presented to all subjects. The results suggest that ear problems may be increased in pregnancy, particularly for hypotensive pregnant women. However, even for pregnant women complaining of ear problems, pure-tone audiometry and impedance audiometry showed normal hearing in all cases. Furthermore, these women's complaints resolved completely on delivery of their babies.
How uncomfortable are the various positions recommended for the instillation of nose drops?
Authors: Kubba Haytham 
Published: November 2007

AbstractNose drops are widely used in the topical treatment of nasal disorders. Their efficacy has previously been shown to depend on the position of the head adopted during instillation. All three of the commonly recommended head positions (head back, praying-to-Mecca, Mygind's) are uncomfortable, and this may affect patient compliance. As yet, no assessment has been made of the discomfort encountered by patients. Twenty adults from a general otolaryngology clinic were asked to adopt each of three positions and then rate the discomfort experienced on a 10 cm visual analogue scale. The results show that although Mygind's position is well tolerated, the praying-to-Mecca position was significantly more uncomfortable than any other. In the absence of any evidence that the praying-to-Mecca position is clinically more efficacious than Mygind's, it seems inappropriate to continue to advocate its use.
Metronidazole ototoxicity - report of two cases
Authors: Iqbal S. M. , Murthy J. G. , Banerjee P. K. , Vishwanathan K. A. 
Published: November 2007

AbstractTwo cases of bilateral moderate to severe sensorineural hearing loss due to oral administration of metronidazole are reported. There has been only one case report of deafness following metronidazole therapy in the world literature. The hearing loss recovered gradually in a period of four to six weeks following withdrawal of drug and oral steroid therapy. The possible mechanism of ototoxicity is discussed. Awareness by the treating physician of ototoxicity due to any drug is stressed.
Adult tracheocele with large cervical presentation
Authors: Mathur N. N. , Sardana Pawan , Singh V. P. , Bais A. S. 
Published: November 2007

AbstractA case is described in which a middle-aged male presented with a large tracheocele in the neck arising from the right postero-lateral aspect of trachea at the level of T2 vertebra. It was not associated with any predisposing factors and except for the swelling in the neck the patient was asymptomatic. It was excised completely through the cervical approach and there has been no recurrence in two years follow-up.
An unusual case of Pneumocystis carinii presenting as an aural mass
Authors: Patel Suresh K. , Philpott J. M. , McPartlin D. W. 
Published: November 2007

AbstractExtrapulmonary involvement of organs with the protozoan Pneumocystis carinii is rare. We describe a case of Pneumocystis carinii presenting as an erosive aural mass in a young male patient with acquired immunodeficiency syndrome. As far as the authors are aware such an example has never been described in a British journal and is the first case worldwide where otic pneumocystosis has extended into the middle cranial fossa. We also present a review of the literature on otological manifestations of Pneumocystis carinii.
Uncommon otological manifestations of nasopharyngeal carcinoma
Authors: Low W. K. , Goh Y. H. 
Published: November 2007

AbstractNasopharyngeal carcinoma (NPC) is significant for the otologist although the nasopharynx is located outside the anatomical confines of the ear. Middle-ear effusion resulting from NPC is well-known. There are however, other less common ear symptoms of NPC that many physicians are not sufficiently aware of. A personal series of patients with NPC presenting with uncommon symptoms relating to the ear is presented. These include NPC presenting as a) haemotympanum b) a peri-auricular mass c) referred sensation to the ear d) blocked ear e) barotrauma f) an ear polyp g) sudden sensorineural hearing loss. These symptoms may pose diagnostic difficulties, resulting in the diagnosis of NPC being delayed. It was concluded that a high index of suspicion for NPC is warranted in high risk patients presenting with unexplained otological symptoms.
The use of nasal endoscopy to control profuse epistaxis from a fracture of the basi-sphenoid in a seven-year-old child
Authors: Bateman N. , Jones N. S. 
Published: November 2007

AbstractA seven-year-old child sustained a fracture of her basisphenoid resulting in profuse, life-threatening haemorrhage which could not be controlled with a post-nasal pack. The fracture site was identified using rigid endoscopy and packed with oxidized cellulose, resulting in immediate control of the haemorrhage. The use of the nasal endoscope in the management of posterior epistaxis is discussed.