bluuebunny/crossref_metadata_2025_split huggingface dataset:
Light sensitivity in PANi/TiO2 double nanolayer
Authors: Huyen Duong Ngoc , Tuan Mai Van , Dung Mai Xuan 
Published: April 2024

Abstract
A double layer of polyaniline (PANi) and titanium dioxide (TiO2) made on glass substrate is used to study the effect of photoinduction in TiO2 on the double layer conductance. The light sources are LEDs emitting monochromatic light peaking around 369, 396, 447 and 663 nm. Raman and UV-Vis spectra show that the electronic structure of PANi in the double layer is modified as a result of the TiO2 coupling. The conductance of the PANi and PANi/TiO2 double layer is found to be sensitive to the light irradiated and depends on the light wavelength. Upon exposure to the light, the conductance of the PANi monolayer is increased while the PANi/TiO2 double layer is decreased with 369, 396 and 447 nm but increased with 663 nm monochromatic light. The change in conductance of the PANi and PANi/TiO2 double layer is accounted for the combination of the carriers arisen from photoelectric effect in PANi and the carrier added/extracted from PANi as a result of photoinduced effect in TiO2 as the layer activated by light.
Extracts from Capsicum annuum as Natural sensitizer in Dye Sensitized Solar Cell : Theoretical analysis using DFT and TD-DFT
Authors: Espinoza-Curilen Oscar Matias , Thompson Sade White , Manidurai Paulraj , Paredes-Gil Katherine 
Published: April 2024

Abstract

Sensitizers derived from Capsicum annum were studied using computational methods (DFT and TD-DFT) for their potential application in DSSC. The UV-Vis computed spectra describe a band around 450 nm that involves a π-π* electronic transition associated with the frontier orbitals HOMO -LUMO localized in the large chain of double bonds of the capsorubin and capsanthin. This very much coincides with the experimental values and shows a potential activity for the photoexcitation. Moreover, the behaviour towards the adsorption and electron injection of the Capsicum annuum to TiO2 semiconductor was analyzed through periodic calculations of the capsorubin@(TiO2)72, capsanthin@(TiO2)72 and capsaicin@(TiO2)72 models. The first two show an opposite result for the capsaicin sensitizer. Specifically, hydrogen bonds were found between the methyl substituents of the carotenoids and the oxygen on the TiO2 surface, suggesting an O-H electrostatic interaction. Capsaicin was found to lose linearity around the amide group (C-NH-CO 180°), transforming into an angular rearrangement (C-NH-CO 120°). These structural changes influence the electronic injection of Capsicum annuum into the TiO2 semiconductor. Thus, the low efficiency reported in carotenoid is due to the presence of weak interactions.
Autoimmune markers have a certain value to assess thyroid function in type 1 diabetes children
Authors: Song Wei 
Published: April 2024

Abstract

Background
Examine risk factors for thyroid dysfunction in children with type 1 diabetes mellitus (T1DM).
Methods
Altogether, 73 Chinese children were examined at the onset of T1DM and after 12 months. Thyroid hormone levels and other biochemical data were measured. Data were compared based on thyroid status.
Results
C-peptide, hemoglobin A1c (HbA1c), free triiodothyronine, and free (unbound) thyroxine levels did not change during the study period. Antibodies to glutamic acid decarboxylase were found in 31.8%, autoantibodies to insulin in 22.7%, islet cell antibodies in 0%, thyroid peroxidase antibodies in 35.3%, and anti-thyrotropin receptor antibodies in 5.9% of subjects. Mean concentrations of anti-thyrotropin receptor antibody and thyroid peroxidase antibody were significantly higher in hyperthyroid children than euthyroid children. However, free thyroxine, thyroid-stimulating hormone, anti-thyrotropin receptor antibody, and anti-thyroid peroxidase antibody concentrations were similar between hypothyroid and euthyroid children.
Conclusions
Positive thyroid peroxidase antibody is higher in children with T1DM than normal children. The presence of thyroid peroxidase antibody and glutamic acid decarboxylase antibodies may lead to poorly controlled diabetes. Finally, T1DM children with thyroid peroxidase antibody were less likely to develop hypothyroidism after onset of diabetes within a one-year follow-up.
A SGM-IHB approach for nonlinear free and forced vibration analysis of FG-GPLRC beams rested on viscoelastic foundation
Authors: Wang Ruihua , Zhong Rui , Wang Qingshan 
Published: April 2024

Abstract

Combining the spectral geometry method and the incremental harmonic balance method (IHB), the nonlinear analytical model of functionally graded graphene platelet reinforced composite (FG-GPLRC) beams is developed in this paper. Nonlinear free and forced vibration characteristics are studied based on this model containing viscoelastic foundation and geometric nonlinear factors. Geometric nonlinear strain-displacement relationship and Lagrangian energy generalization for the FG-GPLRC beam structure are derived according to the Von-Kármán and Timoshenko theories. The IHB method is applied to track the nonlinear vibration response solution of the reduced-order model, which is constructed by introducing linear modal components into the overall nonlinear dynamic equation of the FG-GPLRC beam. Through comparison of the present solution with those from numerical method and literature, the correctness of the established nonlinear analytical model is evidenced. Further, the influence of material-, geometry-, foundation-related parameters and boundary constraints on the nonlinear frequency parameter and amplitude-frequency response of FG-GPLRC beams rested on viscoelastic foundation is analyzed, which can serve as a theoretical guide for designing and evaluating the dynamic environment adaptation of FG-GPLRC beams.
Major cardiovascular events in long-term multiple myeloma survivors: A Korean case- control study (The CAREMM-2105 study)
Authors: Ha Jeonghoon , Choi Suein , Moon Seulji , Han Jinseon , Lee Jeongyoon , Baek Ki-Hyun , Han Seunghoon , Park Sung-Soo , Min Chang-Ki 
Published: April 2024

Abstract

Purpose: Despite improvements in multiple myeloma (MM) survival rates, data on cardiovascular outcomes in long-term survivors remain lacking.Methods: This retrospective case-control study utilized the Korean National Health Insurance Service database (2009–2020) to compare the incidence of cardiovascular disease (CVD) between patients with MM and a matched control group, focusing on long-term (>5 years) survivors. A preliminary case cohort (n=15,402 patients with MM) and a matched control cohort (n=123,216 patients without MM) were established based on birth year and sex. Following 1:1 propensity score matching, the final matched cohorts each comprised 15,402 participants.Results: The case and control cohorts were comparable in mean age (66.2±11.5 years vs. 66.1±11.3 years), sex, age distribution, and comorbidities. By the 8-year follow-up, the cumulative incidence of CV events (12.5% vs. 22.1%) and CVD risk were significantly lower in the case cohort. The 5-year landmark analysis revealed significant differences in CVD incidence between the cohorts (7.8% [case cohort] vs. 9.8% [control cohort]), with variations across age groups and sex, highlighting a significantly higher CVD risk among patients aged <50 years in the case cohort (P<0.001).Conclusions:These findings underscore the need for vigilant CVD monitoring in MM long-term survivors, particularly those aged <50 years at first diagnosis.Implication for Cancer Survivors: This study highlights the importance of integrating cardiovascular monitoring and risk management into long-term care for MM survivors, with a focus on younger patients and personalized interventions.
Prominent ethylene glycol sensing of sol-gel derived ZnO and ZnO:Cu nano-structures
Authors: Karouei Seyedeh Faezeh Hashemi , Shaddoust Mahdi , Khatibani Abbas Bagheri , Rezapour Arefeh , Ahmadi Mohammad Hadi 
Published: April 2024

Abstract

Within this work, pristine zinc oxide and copper-doped powders were prepared using a sol–gel technic. Important physical properties such as morphological, optical, and structural features of the samples have been studied. Different data including X-ray diffraction (XRD), field emission scanning electron microscopy (FESEM), energy dispersive X-ray spectroscopy (EDX), and Brunauer–Emmett–Teller analysis (BET), UV–Vis spectrophotometry, and Fourier transform infrared spectroscopy (FTIR) were collected to investigate the physical features of the samples. In addition, the ethylene glycol vapor sensing capability of the prepared samples was investigated and compared with other vapors like as ethanol, methanol, acetone, isopropanol, and dimethylformamide. The results demonstrated that the samples have a very good selectivity to ethylene glycol (up to 50 times for ZnO and 13 times for ZnO:Cu 20%). The most important parameter of sensing namely operating temperature, real-time variation, sensitivity, and response/recovery times were also evaluated for pristine zinc oxide and copper-doped nano-structures. Specifically, the ZnO nano-structure sensor represented prominent sensitivity of about 37 and 139 towards for ethylene glycol concentration of 200 and 700 ppm, respectively.
Effect of temperature on the mixed mode I/II translaminar fracture of laminated composites reinforced with natural fibers
Authors: Zeinedini Afshin , Hassan Yosra Basim 
Published: April 2024

Abstract

In recent years, laminated composites reinforced with natural fibers have extensively used in the various industries. One of the most important failure modes of laminated composite materials is translaminar fracture under different loading conditions. In this research, the effect of temperature on the translaminar critical strain energy release rate (CSERR) of the composites reinforced with cotton fibers was investigated. The cotton/epoxy samples were placed at different temperature conditions of 30, 0, and − 30°C. The translaminar CSERR values of cotton/epoxy laminated composites were obtained under pure mode I, mixed mode I/II with two different loading angles, and pure mode II loading conditions. To calculate the translaminar CSERR based on experimental results, numerical modeling was also performed. Besides, a modified version of Mixed Mode Fracture Envelope criterion was proposed to predict the mixed mode I/II translaminar fracture behavior of the cotton/epoxy laminated composites at the mentioned temperatures. The results showed that lowering the temperature has a great impact on the translaminar CSERR. It was also concluded that the change in the temperature had the greatest effect on the value of the mode I translaminar CSERR. Moreover, as the temperature decreased from 30 to 0 and − 30°C, the value of the mode I translaminar CSERR decreased around 80 and 90%, respectively.
Overexpression of dehydroascorbate reductase gene IbDHAR1 improves the tolerance to abiotic stress in sweet potato
Authors: Cheng Qirui , Zou Xuan , Wang Yuan , Yang Zhe , Qiu Xiangpo , Wang Sijie , Yang Yanxin , Yang Dongjing , Kim Ho Soo , Jia Xiaoyun , Li Lingzhi , Kwak Sang-Soo , Wang Wenbin 
Published: April 2024

Abstract

Dehydroascorbate reductase (DHAR), an indispensable enzyme in the production of ascorbic acid (AsA) in plants, is vital for plant tolerance to various stresses. However, there is limited research on the stress tolerance functions of DHAR genes in sweet potato (Ipomoea batatas [L.] Lam). In this study, the full-length IbDHAR1 gene was cloned from the leaves of sweet potato cultivar Xu 18. The IbDHAR1 protein is speculated to locate in both the cytoplasm and the nucleus. As revealed by qRT-PCR, the relative expression level of IbDHAR1 in the proximal storage roots was much greater than in the other tissues, and could be upregulated by high-temperature, salinity, drought, and abscisic acid (ABA) stress. The results of pot experiments indicated that under high salinity and drought stress conditions, transgenic Arabidopsis and sweet potato plants exhibited decreases in H2O2 and MDA levels. Conversely, the levels of antioxidant enzymes APX, SOD, POD, and ACT, and the content of DHAR increased. Additionally, the ratio of AsA/DHA was greater in transgenic lines than in the wild type. The results showed that overexpression of IbDHAR1 intensified the ascorbic acid-glutathione cycle (AsA-GSH) and promoted the activity of the related antioxidant enzyme systems to improve plant stress tolerance and productivity.
Ablation of the integrin CD11b mac-1 limits deleterious responses to traumatic spinal cord injury and improves functional recovery in mice
Authors: Li Yun , Ritzel Rodney M. , He Junyun , Liu Simon , Zhang Li , Wu Junfang 
Published: April 2024

Abstract
Background: Spinal cord injury (SCI) causes long-term sensorimotor deficits and posttraumatic neuropathic pain, with no effective treatment. In part, this reflects an incomplete understanding of the complex secondary pathobiological mechanisms involved. SCI triggers microglial/ macrophage activation with distinct pro-inflammatory or inflammation-resolving phenotypes, which potentiate tissue damage or facilitate functional repair, respectively. The major integrin Mac-1 (CD11b/CD18, αMβ2 or CR3), a heterodimer consisting of αM (CD11b) and β2 (CD18) chains, is generally regarded as a pro-inflammatory receptor in neurotrauma. Multiple immune cells of the myeloid lineage express CD11b, including microglia, macrophages, and neutrophils. In the present study, we examined the effects of CD11b gene ablation on posttraumatic neuroinflammation and functional outcomes after SCI.
Methods: Young adult age-matched female CD11b knockout (KO) mice and their wildtype (WT) littermates were subjected to moderate thoracic spinal cord contusion. Neuroinflammation in the injured spinal cord was assessed with qPCR, flow cytometry, NanoString, and RNAseq. Neurological function was evaluated with the Basso Mouse Scale (BMS), gait analysis, thermal hyperesthesia, and mechanical allodynia. Lesion volume was evaluated by GFAP-DAB immunohistochemistry, followed by analysis with unbiased stereology.
Results: qPCR analysis showed a rapid and persistent upregulation of CD11b mRNA starting from 1d after injury, which persisted up to 28 days. At 1d post-injury, increased expression levels of genes that regulate inflammation-resolving processes were observed in CD11b KO mice. Flow cytometry analysis of CD45intLy6C-CX3CR1+ microglia, CD45hiLy6C+Ly6G- monocytes, and CD45hiLy6C+Ly6G+ neutrophils revealed significantly reduced cell counts as well as reactive oxygen production in CD11b KO mice at d3 post-injury. Further examination of the injured spinal cord with NanoString Mouse Neuroinflammation Panel and RNAseq showed upregulated expression of pro-inflammatory genes, but downregulated expression of the reactive oxygen species pathway. Importantly, CD11b KO mice exhibited significantly improved locomotor function, reduced cutaneous mechanical/thermal hypersensitivity, and limited tissue damage at 8 weeks post-injury.
Conclusion: Collectively, our data suggest an important role for CD11b in regulating tissue inflammation and functional outcome following SCI. Thus, the integrin CD11b represents a potential target that may lead to novel therapeutic strategies for SCI.
Mathematical Modelling of COVID-19 Pandemic Putting into consideration Pathogens in the Environment
Authors: Chamber Nuraddeen suleiman mohd , Hasssan shitu 
Published: April 2024

Abstract

We develop a compartmental epidemic mo del which takes into consideration hospitalized individuals and pathogens in the environment that describes a more realistic mathematical model for understanding the trans mission dynamics and control of COVID-19 in Nigeria. The next generation matrix approach is used to determine the control reproduction number (R0C) which we found to be 2.76 implying that the pandemic will persist in the absence of strong control measures. Rigorous mathematical analysis is used to study several properties of the model. We also studied the sensitivity analysis of the model parameters to know the parameters that have a high impact on the reproduction number (R0C). The model was parameterized using COVID-19 data published by Nigeria Center for Disease Control (NCDC). The numerical simulation also carried out to verify the theoretical results. The model shows that the hospitalized individuals and pathogens in the environment have positive impact on the control reproduction number (R0C).
Effects of sexual counseling and education based on self-efficacy theory on the sexual function of women with breast cancer
Authors: Jamshidi Azadeh , Gharibi Taiebeh , Noroozi Farzaneh , Bagherzadeh Razieh 
Published: April 2024

Abstract

Background: The diagnosis and treatment of breast cancer are associated with side effects that can affect patients' self-efficacy and various aspects of their quality of life, including their sexual function. Therefore, this study was conducted with the aim of investigating the effect of sexual counseling and education based on self-efficacy theory on the sexual function of women with breast cancer.
Method: This randomized controlled trial used a pretest, posttest, control group, and one-month follow-up design. It included 45 female breast cancer survivors, recruited from the clinics and hematology wards of Bushehr, Iran. The inclusion criterion was that at least three months should have passed since the last chemotherapy/radiotherapy. The participants were randomly assigned to two experimental and control groups. The experimental group received two training sessions and three counseling sessions based on efficacy theory. A demographic information form and a female sexual function index questionnaire were used for data collection, and the participants completed the questionnaire in the pretest, posttest, and follow-up stages. Chi-square, Mann–Whitney U, repeated-measures ANOVA, and Fisher's Least Significant Difference (LSD) test were used to analyze the data. P<0.05 was considered statistically significant.
Result: At the posttest stage, statistically significant improvements were noted in the intervention group for arousal (P<0.001), orgasm (P = 0.008), sexual satisfaction (P<0.001), and overall FSFI score (P<0.001), which did not have a significant statistical difference until the follow-up stage. In the control group, the overall FSFI score, orgasm, and sexual satisfaction decreased at follow-up compared to those of the pretest and posttest.
Conclusion: The scores of overall FSFI and most of its domains were higher in the experimental group than in the control group, an ability that can be attributed to the effect of sexual education and counseling. It is recommended to use this non-invasive, low-cost, and easy method together with other medical procedures.
Addressing evidence needs during health crises in the province of Quebec (Canada): a proposed action plan for rapid evidence synthesis
Authors: Hong Quan Nha , McSween-Cadieux Esther , Guillette Maxime , Manceau Luiza Maria , Li Jingjing , Granikov Vera , Pomey Marie-Pascale , Gagnon Marie-Pierre , Ziam Saliha , Dagenais Christian , Dagenais Pierre , Lesage Alain , Poder Thomas G. , Drapeau Martin , Ridde Valéry , Lane Julie 
Published: April 2024

Abstract

Background: The COVID-19 pandemic necessitated the rapid availability of evidence to respond in a timely manner to the needs of practice settings and decision-makers in health and social services.
Now that the pandemic is over, it is time to put in place actions to improve the capacity of systems to meet knowledge needs in a situation of crisis. The main objective of this project was thus to develop an action plan for the rapid syntheses of evidence in times of health crisis in Quebec (Canada).
Methods: We conducted a three-phase collaborative research project. First, we carried out a survey with producers and users of rapid evidence syntheses (n=40) and a group interview with three patient partners to prioritize courses of action. In parallel, we performed a systematic mapping of the literature to identify rapid evidence synthesis initiatives developed during the pandemic. The results of these two phases were used in a third phase, in which we organized a deliberative workshop with 26 producers and users of rapid evidence syntheses to identifying ways to operationalize priorities. The data collected at each phase were compared to identify common courses of action and integrated to develop an action plan.
Results: A total of 14 specific actions structured into four main axes were identified over the three phases. In axis 1, actions on raising awareness of the importance of evidence-informed decision-making among stakeholders in the health and social services network are presented. Axis 2 includes actions to promote optimal collaboration of key stakeholders in the production of rapid evidence synthesis to support decision-making. Actions advocating the use of a variety of rapid evidence synthesis methodologies known to be effective in supporting decision-making are presented in axis 3. Finally, axis 4 is about actions on the use of effective strategies to promote the dissemination, sharing, and use of rapid evidence synthesis products to support decision-making.
Conclusions: This project led to the development of a collective action plan aimed at preparing the Quebec ecosystem and other similar jurisdictions to meet knowledge needs more effectively in times of health emergency. The implementation of this plan and its evaluation will enable us to continue to fine-tune it.
Association Between dietary iron Levels and all-cause and cancer-cause mortality: a Prospective Cohort Study
Authors: Yi Jiahong , Guo Hui , Yang Lin , Jiang Chang , Duan Junyi , Ju Xue , Zhao Yue , He Wenzhuo , Xia Liangping 
Published: April 2024

Abstract
Although there are many studies concentrate on the connection between dietary iron and tumors. Few studies elucidated the association between total dietary iron and all-cause or cancer-cause mortality. Conclusions about how total dietary iron influences all-cause/cancer-cause mortality were paradoxical. Our study collected dietary iron and survival data from National Health and Nutrition Examination Survey (NHANES) 1999-2019. Multivariate Cox proportional risk models and subgroup analysis were used to assess the relationship between dietary iron and all/cancer-cause death. Restricted Cubic Samples (RCS) were used to fit the non-linear relationship between them. Dietary iron was a protective factor against all-cause mortality ( p for trend = 0.004), as well as cancer-cause mortality( p for trend = 0.028). Dietary iron content had a nonlinear relationship with and all-cause mortality (p for overall < 0.001; p for non-linearity < 0.001) with an "L" curve, so as to the cancer-related death (p for overall=0.002，p for non-linearity= 0.046). The nonlinear association of dietary iron and cancer-cause mortality differed from all/cancer-cause mortality.Our study found that dietary iron was a protective factor for death of all-cause and cancer in population and they had an "L" shaped nonlinear curves. All-cause/cancer mortality was attenuated by dietary iron in people who were aged <=65 years, males, Non-Hispanic White and Non-Hispanic Black, as well as people without hypertension or diabetes mellitus(DM).