bluuebunny/crossref_metadata_2025_split huggingface dataset:
Efeitos adversos dos fármacos inibidores da enzima conversora de angiotensina no tratamento da Hipertensão Arterial Sistêmica: uma revisão integrativa
Authors: Silva Márcia Pedro da , Silva Ramille Araújo da , Dodó Francisco Diemeson Bezerra , Moraes Dante de Matos , Medeiros Lívia Furtado , Oliveira Raimunda Moreira de , Júnior Odeon Parente Aguiar , Menezes Letícia Soares Teles de , Carvalho Fabiane Caxias de Paula , Rodrigues David Jeivan Santos , Silva Francisco Gabriel Santos da , Martins Wascelys Bernardino , Araújo Luana Hellen Bezerra de Sousa , Santos Gabriella Giacomini Allemany dos , André Leandro Oliveira , Leite Gustavo dos Reis , Vasconcelos André Vinícius , Botelho João Gabriel Rodrigues , Salgueiro Ana Julia Veras 
Published: February 2025

A Hipertensão Arterial Sistêmica é uma doença silenciosa, responsável por um alto índice de morbidade no Brasil e no mundo. Nesse sentido, tendo em vista os potenciais agravos à saúde decorrentes do tratamento ineficaz dessa condição, diversas classes de fármacos tem sido empregadas como medidas terapêuticas, destacando-se, nesse esteio, os fármacos inibidores da enzima conversora de angiotensina (IECA). Nesse contexto, o objetivo deste estudo foi analisar a produção científica acerca dos efeitos colaterais decorrentes do tratamento de hipertensão arterial sistêmica com fármacos inibidores da ECA. Para tanto, foi empreendida uma revisão integrativa de literatura, e os principais achados foram discutidos à luz da literatura atual. Nesse esteio, foi evidenciado que a associação entre as diversas classes de fármacos anti-hipertensivos é capaz de desencadear efeitos adversos complexos, os quais se relacionam com os mecanismos de ação de cada medicamento. No que se refere aos inibidores da ECA, os principais efeitos colaterais evidenciados dizem respeito à tosse, ao angioedema e à hipercalemia. Todavia, apesar da incidência relativamente comum desses sinais e sintoma, os resultados observados nos estudos revisados permitem concluir que os inibidores da ECA são fármacos seguros e eficazes para serem utilizados no tratamento da hipertensão arterial.
Exploring Algerian EFL Students’ Familiarity, Use and Attitudes towards Generative Artificial Intelligence Tools in Education
Authors: SEBBAH Loubna 
Published: February 2025

It is agreed nowadays that Artificial intelligence (AI) has gained wider acclamation in various sectors, including education. The integration of AI in education has unveiled an array of AI-powered tools, revolutionizing teaching and learning and equipping both students and teachers to navigate the demands of the digital era. Within the framework of the Technology Acceptance Model, the present study aims to explore Algerian EFL students’ familiarity, use and attitudes towards artificial intelligence tools and chatbots in the learning process. To this end, an exploratory study involving a mixed-methods design was conducted with 305 graduate and undergraduate EFL subjects in the Department of English of the University of Algiers 2. The results emerging from the quantitative and qualitative analysis of the questionnaire revealed that the subjects were familiar with different AI tools, such as Chatbots and generative tools, mainly using them to complete tasks requiring both lower and higher-order thinking skills. The subjects generated positive attitudes towards the use of AI, favouring their efficiency and support but expressing concerns about potential over-reliance and impacts on their motivation, critical thinking skills and creativity. The study concludes with suggestions for future research on the ethical implications and best practices for AI use in higher education.
The Negative Cross-Linguistic Influence of Arabic on the English Written Productions of Algerian Novice Learners
Authors: GOUIDER Ilyes 
Published: February 2025

This study explores the impact of Arabic on the English written output of Algerian pupils. It focuses primarily on disclosing the nature of the influence on the levels of lexis, grammar, and writing conventions of English and attempts to identify the main sources responsible for such linguistic deviations. The methodology involves a qualitative, corpus-based study of written compositions from 98 fourth-grade pupils at an Algerian middle school. The analysis was conducted through the adoption of error analysis and thematic analysis techniques while incorporating aspects of contrastive analysis to detect the sources of interlingual errors. The results revealed that Arabic influences English writing through script code-switching and transliteration, as well as impacting idiomatic choices, leading to significant lexical and semantic divergences. Errors stemming from grammatical differences, such as article omission, copula dropping, and future tense formation, highlighted the contrasts between the Arabic synthetic structures embedded with morphological inflections and English analytic patterns. Additionally, the study identified errors involving prepositions, such as unnecessary additions influenced by Arabic, and writing convention mistakes, including improper capitalization. The findings highlight the necessity of developing strategies to increase learners' awareness of Arabic cross-linguistic interference, thereby enhancing their writing proficiency.
تأويلية اللغة وماهية الحقيقة في أفق الهيرمينوطيقا الأنطولوجية
Authors: مريخي رانيا 
Published: February 2025

يقوم الفهم الكامل للتجربة الوجودية الإنسانية مع العالم والأشياء بوصفها جوهر التفكير وماهيته. ما أدى إلى انعكاس التصوّر حول الحقيقة داخل العمل الفني الذي أضحى فضاءها المطلق وطبيعتها الأولى. تهدف الدراسة، إلى بسط تصوّرات الفلسفة الأنطولوجية في سعيها لاجتراح ماهية اللّغة في تجاوزها للمفاهيم الكلاسيكية. وماهية الحقيقة الوجودية التي لا تتجلّى إلا في إطار العمل الفني. فما هي إسهامات المنجز الأنطولوجي في الدّرس اللغوي ومبحث الحقيقة الإنساني؟ لذلك ارتأينا المقاربة التأويلية وفق التصور الأنطولوجي للوقوف على التجاوزات والإضافات التصورية الفريدة لمبحث اللغة والحقيقة في سياق الفلسفة الوجودية. وخلصت الدراسة إلىأن المدارس اللسانية قد قزّمت الرؤيا إلى اللغة وجعلت منها وسيطا تواصليا من جهة، مثلما فعلت المدارس الجمالية التي اقتصرت الجميل والفن في حدود المتعة الجمالية.
SISTEM PENYIRAMAN OTOMATIS PADA TANAMAN BUAH NAGA BERBASIS INTERNET OF THINGS (IOT)
Authors: Lihana  , Lalu Delsi Samsumar  , Muh Nasirudin Karim  
Published: February 2025

Penelitian ini mengembangkan sistem penyiraman otomatis berbasis Internet of Things (IoT) untuk tanaman buah naga, bertujuan meningkatkan efisiensi dan efektivitas perawatan tanaman. Sistem penyiraman yang efisien sangat penting untuk mendukung pertumbuhan buah naga, terutama di kondisi iklim yang bervariasi. Metode penelitian mencakup desain dan implementasi sistem menggunakan NodeMCU ESP32 sebagai mikrokontroler, sensor kelembaban tanah untuk mendeteksi kelembaban, serta pompa air otomatis. Data kelembaban tanah dikirim ke server melalui jaringan Wi-Fi, memungkinkan pemantauan dan pengendalian jarak jauh. Hasil penelitian menunjukkan bahwa sistem dapat mengontrol penyiraman secara otomatis berdasarkan data kelembaban tanah, dengan tingkat akurasi yang baik dan respons cepat terhadap perubahan kondisi tanah. Keunggulan dari sistem ini terletak pada kemampuannya mengurangi kebutuhan intervensi manual dan meningkatkan efisiensi penyiraman. Dengan fitur pengendalian jarak jauh, petani dan penghobi tanaman dapat lebih mudah mengelola kebutuhan air tanaman mereka. Penelitian ini juga membuka peluang untuk pengembangan lebih lanjut, seperti integrasi fitur tambahan yang dapat meningkatkan fungsionalitas sistem. Diharapkan, sistem ini memberikan solusi praktis dan efektif bagi para petani dan penghobi tanaman buah naga, menjawab tantangan dalam perawatan tanaman di era modern yang semakin bergantung pada teknologi.
Estado del arte sobre en el manejo del dolor y la movilidad de pacientes en cuidados paliativos. Una aproximación desde la Fisioterapia.
Authors: Reyes Álvarez Mirian Lisandra 
Published: February 2025

Los cuidados paliativos son esenciales en la atención a pacientes con enfermedades terminales; para mejorar su calidad de vida y aliviar el sufrimiento, la fisioterapia se presenta como una herramienta que contribuye al bienestar integral de los pacientes en este contexto. El objetivo de esta revisión sistemática es describir el estado del arte en el manejo del dolor y la movilidad de los pacientes en cuidados paliativos, una aproximación desde la Fisioterapia, explorando cómo esta disciplina contribuye a mejorar su calidad de vida, a través de una revisión exhaustiva de estudios y enfoques terapéuticos que identifiquen las intervenciones fisioterapéuticas más efectivas y su aplicación práctica en pacientes terminales; para ello, se realizó una revisión sistemática en bases de datos científicas sobre los estudios clínicos y experimentales publicados entre enero de 2019 y noviembre de 2024; los criterios de inclusión abarcaban investigaciones que analizaran el uso de la fisioterapia en cuidados paliativos, con mediciones específicas sobre dolor y movilidad. De los 22 estudios incluidos, se encontraron intervenciones eficaces como ejercicios físicos, TENS y masajes, los cuales mostraron mejoras significativas en la reducción del dolor y la mejora de la movilidad. Se concluye que la fisioterapia contribuye significativamente en la calidad de vida del paciente cuidados paliativos, mejorando el dolor y movilidad; los resultados alcanzados son efectivos, sin embargo, se requieren más estudios controlados aleatorios para confirmar la eficacia de estas intervenciones y optimizar tratamientos personalizados.
Palabras clave: Cuidados Paliativos, Fisioterapia, Manejo del Dolor, Limitación de la Movilidad, Enfermedad Crónica.
Machine Learning for Temperature Analysis in Ouagadougou: A Random Forest Perspective
Authors: Ali Guma , Robert Wamusi 
Published: February 2025

Temperature variety analysis is pivotal for understanding climate patterns and foreseeing future changes especially in parched and semiarid regions This study investigates the application of the RF algorithm for temperature prediction in Ouagadougou Burkina Faso leveraging historical climate data The demonstrate is prepared on Climate Investigate Unit CRU data to evaluate its prescient performance in capturing seasonal and long-term temperature patterns Comparative analysis is conducted to evaluate the viability of RF against conventional forecasting strategies The results show that the RF model illustrates tall predictive accuracy making it a dependable tool for temperature estimating in bone-dry climates These discoveries contribute to climate versatility techniques and decision-making for sustainable natural arranging within the region.
Pengaruh Budaya Organisasi dan Iklim Organisasi terhadap Efektivitas Kinerja pada Pegawai Kantor Camat Kecamatan Gunung Kijang
Authors: Amelia Risky , Armansyah Armansyah , Rizki Muhammad , Sihombing Agustinus , Fatahuddin Fatahuddin 
Published: February 2025

Penelitian ini bertujuan untuk mengetahui Pengaruh budaya organisasi dan iklim organisasi terhadap efektivitas kinerja pegawai. Metode yang digunakan dalam penelitian ini adalah metode penelitian kuantitatif yaitu penelitian yang menekankan pada pengujian teori-teori dan hipotesis-hipotesis melalui pengukuran variabel-variabel penelitian dalam angka (Quantitative). Populasi dalam penelitian ini seluruh pegawai Kantor Camat Kecamatan Gunung Kijang yang berjumlah 48 pegawai dan yang menjadi sampel 39 pegawai yang telah memenuhi kriteria masa kerja lebih dari tiga tahun. Hasil dalam penelitian ini menunjukkan bahwa, hasil uji parsial (uji t) menunjukkan budaya organisasi memiliki nilai signifikansi 0,000 < 0,05,dan nilai thitung 3,836 > ttabel 2,028, iklim organisasi memiliki nilai signifikansi 0,000 < 0,05. dan nilai thitung 4,471 > ttabel 2,028, Hasil uji simultan (uji F) menunjukkan budaya organisasi dan iklim organisasi memiliki nilai signifikansi 0,000 < 0,05,dan nilai thitung 72,788 > ttabel 3,26. Dan uji determinasi dengan nilai adjusted R square sebesar 0,791. Berdasarkan hasil penelitian maka dapat disimpulkan bahwa secara parsial (Uji t) budaya organisasi berpengaruh terhadap efektivitas kinerja, iklim organisasi berpengaruh terhadap efektivitas kinerja. Hasil uji simultan (Uji F) budaya organisasi dan iklim organisasi berpengaruh terhadap efektivitas kinerja. Dan budaya organisasi dan iklim organisasi memengaruhi efektivitas kinerja sebesar 79,1% dan sisanya dipengaruhi oleh variabel lain di luar penelitian ini.
Orofacial Anomalies in Kindler Epidermolysis Bullosa
Authors: Krämer Susanne , Hillebrecht Anna Lena , Wang Yao , Badea Mihail-Alexandru , Barrios Jose Ignacio , Danescu Sorina , Fuentes Ignacia , Kartal Demet , Klausegger Alfred , Ponce de León Enrique , Schilke Reinhard , Yordanova Ivelina , Bloch-Zupan Agnes , Has Cristina 
Published: March 2024

ImportanceKindler epidermolysis bullosa is a genetic skin-blistering disease associated with recessive inherited pathogenic variants in FERMT1, which encodes kindlin-1. Severe orofacial manifestations of Kindler epidermolysis bullosa, including early oral squamous cell carcinoma, have been reported.ObjectiveTo determine whether hypoplastic pitted amelogenesis imperfecta is a feature of Kindler epidermolysis bullosa.Design, Settings, and ParticipantsThis longitudinal, 2-center cohort study was performed from 2003 to 2023 at the Epidermolysis Bullosa Centre, University of Freiburg, Germany, and the Special Care Dentistry Clinic, University of Chile in association with DEBRA Chile. Participants included a convenience sampling of all patients with a diagnosis of Kindler epidermolysis bullosa.Main Outcomes and MeasuresThe primary outcomes were the presence of hypoplastic pitted amelogenesis imperfecta, intraoral wounds, gingivitis and periodontal disease, gingival hyperplasia, vestibular obliteration, cheilitis, angular cheilitis, chronic lip wounds, microstomia, and oral squamous cell carcinoma.ResultsThe cohort consisted of 36 patients (15 female [42%] and 21 male [58%]; mean age at first examination, 23 years [range, 2 weeks to 70 years]) with Kindler epidermolysis bullosa. The follow-up ranged from 1 to 24 years. The enamel structure was assessed in 11 patients, all of whom presented with enamel structure abnormalities. The severity of hypoplastic pitted amelogenesis imperfecta varied from generalized to localized pitting. Additional orofacial features observed include gingivitis and periodontal disease, which was present in 90% (27 of 30 patients) of those assessed, followed by intraoral lesions (16 of 22 patients [73%]), angular cheilitis (24 of 33 patients [73%]), cheilitis (22 of 34 patients [65%]), gingival overgrowth (17 of 26 patients [65%]), microstomia (14 of 25 patients [56%]), and vestibular obliteration (8 of 16 patients [50%]). Other features included chronic lip ulcers (2 patients) and oral squamous cell carcinoma with lethal outcome (2 patients).Conclusions and RelevanceThese findings suggest that hypoplastic pitted amelogenesis imperfecta is a feature of Kindler epidermolysis bullosa and underscore the extent and severity of oral manifestations in Kindler epidermolysis bullosa and the need for early and sustained dental care.
School Bus Rebate Program and Student Educational Performance Test Scores
Authors: Pedde Meredith , Szpiro Adam , Hirth Richard A. , Adar Sara D. 
Published: March 2024

ImportanceStudents who ride older school buses are often exposed to high levels of exhaust during their commutes, which may adversely affect health and school attendance. As a result, the US Environmental Protection Agency (EPA) has awarded millions of dollars to school districts to replace older, highly polluting school buses with newer, cleaner buses.ObjectiveTo leverage the EPA’s randomized allocation of funding under the 2012-2016 School Bus Rebate Programs to estimate the association between replacing old, highly polluting buses and changes in district-average standardized test scores.Design, Setting, and ParticipantsThis study examined changes in reading and language arts (RLA) and math test scores among US school district applicants to the EPA’s 2012-2016 national School Bus Rebate Programs 1 year before and after each lottery by selection status. Data analysis was conducted from January 15 to July 30, 2023.ExposureSelection to receive EPA funding to replace older school buses with newer, cleaner alternatives.Main Outcomes and MeasuresSchool district changes in RLA and math test scores among students in grades 3 through 8 before and after the EPA funding lotteries by selection status were measured using an intention-to-treat approach.ResultsThis study included 1941 school district applicants to the 2012-2106 EPA School Bus Rebate Programs. These districts had a mean (SD) of 14.6 (33.7) schools per district, 8755 (23 776) students per district, and 41.3% (20.2%) of students with free lunch eligibility. Among the applicants, 209 districts (11%) were selected for the clean bus funding. District-average student test scores did not improve among selected districts overall. In secondary analyses, however, districts replacing the oldest, highest polluting buses (ie, pre-1990) experienced significantly greater improvements in district-average test scores in the year after the lottery for RLA and math (SD improvement in test scores, 0.062 [95% CI, 0.050-0.074] and 0.025 [95% CI, 0.011-0.039], respectively) compared with districts without replacements.Conclusions and RelevanceIn this study, the EPA funding was not associated with student test scores overall, but in secondary analyses, the replacement of the oldest school buses was associated with improved educational performance. These findings support prioritizing clean bus replacement of the oldest buses as an actionable way for improving students’ educational performance.
Glucose Oxidase Energized Osmium with Dual‐Active Centers and Triple Enzyme Activities for Infected Diabetic Wound Management
Authors: He Shaobin , Lin Mengting , Zheng Qionghua , Liang Bo , He Xinjie , Zhang Yin , Xu Qiuxia , Deng Haohua , Fan Kelong , Chen Wei 
Published: March 2024

AbstractDiabetic wounds are susceptible to bacterial infections, largely linked to high blood glucose levels (hyperglycemia). To treat such wounds, enzymes like glucose oxidase (GOx) can be combined with nanozymes (nanomaterials mimic enzymes) to use glucose effectively for purposes. However, there is still room for improvement in these systems, particularly in terms of process simplification, enzyme activity regulation, and treatment effects. Herein, the approach utilizes GOx to directly facilitate the biomineralized growth of osmium (Os) nanozyme (GOx‐OsNCs), leading to dual‐active centers and remarkable triple enzyme activities. Initially, GOx‐OsNCs use vicinal dual‐active centers, enabling a self‐cascaded mechanism that significantly enhances glucose sensing performance compared to step‐by‐step reactions, surpassing the capabilities of other metal sources such as gold and platinum. In addition, GOx‐OsNCs are integrated into a glucose‐sensing gel, enabling instantaneous visual feedback. In the treatment of infected diabetic wounds, GOx‐OsNCs exhibit multifaceted benefits by lowering blood glucose levels and exhibiting antibacterial properties through the generation of hydroxyl free radicals, thereby expediting healing by fostering a favorable microenvironment. Furthermore, the catalase‐like activity of GOx‐OsNCs aids in reducing oxidative stress, inflammation, and hypoxia, culminating in improved healing outcomes. Overall, this synergistic enzyme‐nanozyme blend is user‐friendly and holds considerable promise for diverse applications.
Rotation‐To‐Translation Enabled Robust Triboelectric Nanogenerator for Wind Harvesting and Sensing
Authors: He Yalong , Tang Lirong , Zhang Hengchen , Chen Jie , Yang Xiaohong 
Published: March 2024

AbstractDisc and cylinder‐based triboelectric nanogenerators (TENGs) have great potential for harvesting wind energy. However, a significant challenge faced by these TENGs is the wear issues arising from the required close contact between tribo‐materials, especially at high frequencies. In response to this challenge, a gear‐slider TENG (GS‐TENG) is designed to transition from continuous close‐contact friction mode to intermittent contact. Working in unison with the central gear and two sliders, four units housed within GS‐TENG yield electrical output through periodic contact and separation. During a durability test of 845 000 cycles, the short‐circuit current only experiences a slight decrease, going from 25.38 to 24.03 µA, retaining 94.68% of its initial value. Operating at a matched impedance of 6 MΩ, GS‐TENG at M1 achieves a peak power density of 386 mW m−2, exceeding some previously proposed solutions in wind harvesting. When integrated into a wind speed sensing system, the GS‐TENG has a wide sensing range (13.1 to 28 m s−1) with a maximum error of 3.39%. This work demonstrates a rotation‐to‐translation strategy that lays the foundation for long‐term, high‐frequency wind energy harvesting and the development of a self‐powered wind sensing system.
Oh, the places you'll go! A qualitative study of resident career decisions in emergency medicine
Authors: Jordan Jaime , Buckanavage Jack , Ilgen Jonathan , Gottlieb Michael , Hopson Laura R. , Janicki Adam , Curato Mark , Chipman Anne K. , Clarke Samuel O. 
Published: March 2024

AbstractObjectivesPostresidency career choices are complex decisions that involve personal, professional, and financial preferences and may be influenced by training programs. It is unknown how residents navigate these decisions during emergency medicine (EM) residency. We explored EM residents’ perspectives on career decision making and how residency programs can support career planning.MethodsWe conducted semistructured interviews at seven accredited EM residency programs from diverse locations and training formats. We used purposive sampling to reflect the diversity of trainees with regard to gender, level of training, and career plans. Two researchers independently coded the transcripts. We used a constructivist–interpretivist paradigm to guide our thematic analysis.ResultsWe interviewed 11 residents and identified major themes in three categories. Residents described being exposed to career options through formalized curricula such as required rotations, career fairs, and subspeciality tracks, highlighting the importance of access to faculty with diverse areas of clinical and academic expertise. Many noted that exposure was often self‐driven. We identified three major themes regarding career decisions: instrumental factors, people involved, and processes of decision making. Instrumental factors included personal interests, goals, and values as well as practice characteristics, financial considerations, timing, and opportunity costs. Mentors and family were highly involved in resident career decisions. Residents often utilized reflection and conversations with mentors and peers in their decision‐making process. Participants recommended that programs provide exposure to diverse career options early in training, protect time for career education, and ensure adequate mentorship and a supportive community. Participants suggested specific curricular content and strategies to support career decisions.ConclusionsThis study illuminates important factors involved in resident career decision making and how programs can support their trainees. Essential components include diverse experiences and building a reflective mentorship environment.