bluuebunny/crossref_metadata_2025_split huggingface dataset:
Constructing Crown Ether‐Based Supramolecular Adhesives with Ambient‐Temperature Applicable and Durable Adhesion
Authors: Ju Hao , Yin Zhaoliang , Demchuk Zoriana , Bocharova Vera , Gainaru Catalin , Laub Jeffrey A. , Vogiatzis Konstantinos , Advincula Rigoberto , Chen Jiayao , Cao Peng‐Fei 
Published: April 2024

AbstractSupramolecular adhesives are attracting considerable attentions owing to their dynamic and reversible bonding, while the complex curing conditions and poor performance under extreme conditions severely restrict their applicability. Herein, a series of tetra‐crown ether‐terminated polyethylene glycol (TCE‐PEG) adhesives are presented in which plenty of supramolecular interactions, including Van der Waals, hydrogen bonding, π–π staking, metal coordination, and electrostatic ones, provide strong adhesion on multiple types of substrates. Highly relevant for practical applications, ultra‐strong adhesivity of TCE‐PEG can be achieved without requiring additional ultraviolet radiation, heat, or chemical treatment at ambient temperature. It also exhibits durable adhesive behavior, excellent underwater stability, and low‐temperature tolerance. Especially, by incorporating ionic polymer fragments of polyethyleneimine hydrochloride, additional hydrogen bonding between secondary amines and crown ether rings can be induced to enhance the lap‐shear strength to 7.21 MPa due to the formation of supramolecular cross‐linked network. This work pioneers a rather unique supramolecular approach for easily formed, ultra‐strong crown‐ether‐based adhesives bearing great potential for applications in critical environments of limited heat source and unallowed solvent usage.
Construction of a Pt‐CeOx Interface for the Electrocatalytic Hydrogen Evolution Reaction
Authors: Yu Shen‐Wei , Kwon Soonho , Chen Yizhen , Xie Zhenhua , Lu Xiner , He Kai , Hwang Sooyeon , Chen Jingguang G. , Goddard William A. , Zhang Sen 
Published: April 2024

AbstractThe creation of metal‐metal oxide interfaces is an important approach to fine‐tuning catalyst properties through strong interfacial interactions. This article presents the work on developing interfaces between Pt and CeOx that improve Pt surface energetics for the hydrogen evolution reaction (HER) within an alkaline electrolyte. The Pt‐CeOx interfaces are formed by depositing size‐controlled Pt nanoparticles onto a carbon support already coated with ultrathin CeOx nanosheets. This interface structure facilitates substantial electron transfer from Pt to CeOx, resulting in decreased hydrogen binding energies on Pt surfaces, and water dissociation for the HER, as predicted by the density functional theory (DFT) calculations. Electrochemical testing indicates that both Pt specific activity and mass activity are improved by a factor of 2 to 3 following the formation of Pt‐CeOx interfaces. This study underscores the significance and potential of harnessing robust interfacial effects to enhance electrocatalytic reactions.
Li‐Site Defects Induce Formation of Li‐Rich Impurity Phases: Implications for Charge Distribution and Performance of LiNi0.5−xMxMn1.5O4 Cathodes (M = Fe and Mg; x = 0.05–0.2)
Authors: Murdock Beth E. , Cen Jiayi , Squires Alexander G. , Kavanagh Seán R. , Scanlon David O. , Zhang Li , Tapia‐Ruiz Nuria 
Published: April 2024

AbstractAn understanding of the structural properties that allow for optimal cathode performance, and their origin, is necessary for devising advanced cathode design strategies and accelerating the commercialization of next‐generation cathodes. High‐voltage, Fe‐ and Mg‐substituted LiNi0.5Mn1.5O4 cathodes offer a low‐cost, cobalt‐free, yet energy‐dense alternative to commercial cathodes. In this work, the effect of substitution on several important structure properties is explored, including Ni/Mn ordering, charge distribution, and extrinsic defects. In the cation‐disordered samples studied, a correlation is observed between increased Fe/Mg substitution, Li‐site defects, and Li‐rich impurity phase formation—the concentrations of which are greater for Mg‐substituted samples. This is attributed to the lower formation energy of MgLi defects when compared to FeLi defects. Li‐site defect‐induced impurity phases consequently alter the charge distribution of the system, resulting in increased [Mn3+] with Fe/Mg substitution. In addition to impurity phases, other charge compensators are also investigated to explain the origin of Mn3+ (extrinsic defects, [Ni3+], oxygen vacancies and intrinsic off‐stoichiometry), although their effects are found to be negligible.
Interfacial Electronic and Magnetic Reconstructions in Manganite/Titanate Superlattices
Authors: Lan Da , Yao Bingqing , Swamynadhan M. J. , Li Ning , Cao Jing , Shi Shu , Yu Xiaojiang , Yang Ping , Wu Xiaohan , Liu Chao , Chen Pingfan , Chen Jingsheng , Ghosh Saurabh , He Qian 
Published: April 2024

AbstractComplex oxide heterointerfaces provide a spacious arena for creating emergent phenomena that are unattainable in the constituent bulk counterparts. Herein, The BaTiO3/La1‐xSrxMnO3 [BTO/LSMO (x)] superlattice (SL) as a model system to investigate the intimately coupled interfacial effects and their resultant phenomena is focused on. The experimental and Density Functional Theory (DFT) calculations reveal that the induced magnetism on Ti originates from both the charge transfer process between Mn and Ti at the titanate/manganite heterointerfaces and the cation intermixing, both contributing comparably to the overall magnetic effect. Upon changing x, the orbital reconstruction of the Mn 3d electrons, tailored by the strain state of the LSMO (x) layers, efficiently modifies the magnetic exchange coupling between Mn–Ti and Mn–Mn at the interfaces, which are proved to account for the modulations of the macroscopic magnetism of the SLs. This work demonstrates the significance of interfacial reconstructions for magnetism, paving a new pathway to manipulate the magnetic properties of artificial oxide heterostructures.
Deactivation of Partially (dis)Charged LNMO in Contact with Water by Electrochemical Protonation of Li(1 − x)Ni0.5Mn1.5O4
Authors: Pitillas Andrea I. , De Taeye Louis L. , Vereecken Philippe M. 
Published: April 2024

AbstractThe development of water‐based composite cathode slurries for Li‐ion batteries is hindered by adverse interactions between the battery active material and water. Insights into interactions between H2O and LiNi0.5Mn1.5O4 (LNMO) are studied using a thin‐film model system. The reactivity of this active material with H2O is evaluated at different lithiation states, showing that protonation of the active material in aqueous environments is electrochemically driven, rather than a chemical Li+/H+ ion exchange reaction. The electrochemically driven mechanism describing the protonation of LNMO is only present when the material is in its partially delithiated form. These findings suggest it is possible to cast this material from an aqueous precursor when lithiated, as long as there are no traces of it when the electrochemical delithiation (cell charging) is carried out.
Visible TADF and NIR Quenching Emission of Chromium Activated Zirconium‐Halide Perovskite Toward Ultra‐High‐Sensitive Ratiometric Fluorescent Thermometer
Authors: Zhao Suxin , Sang Kaihang , Yang Ye , Zhang Junfang , Hu Yangxiang , Chen Mianhong , Zhang Xinguo , Pang Qi , Zhou Liya , Chen Peican 
Published: April 2024

AbstractWith the development of science and technology, the measurement of temperature is receiving more and more attention. However, ratiometric fluorescent thermometers based on thermally coupled energy levels remain challenging because of their low relative sensitivity (Sr). In this work, chromium activated zirconium‐halide perovskite Cs2ZrCl6 microcrystals are successfully synthesized via a simple co‐precipitation method at room temperature. Interestingly, the host Cs2ZrCl6 exhibits reverse thermal quenching due to its thermal‐activated delayed fluorescence (TADF) behavior, while the Cr3+ dopant shows normal thermal quenching. Leveraging the difference in their temperature‐dependent luminescent properties, a ratiometric fluorescent thermometer is ingeniously developed, whose Sr reaches a maximum of 4.23% K−1. Besides, the as‐synthesized thermometer is demonstrated for mobile phone remote temperature measurement. This finding offers a new approach for the design of high‐sensitivity ratiometric fluorescent temperature sensors.
Magnetophotoluminescence Response Triggered by the Triplet State in Metallofullerene
Authors: Zheng Chaofeng , Li Guixian , Liang Jiayi , Yu Lu , Li Wang , Han Yibo , Wang Chunru , Wang Taishan 
Published: April 2024

AbstractThis paper reports the discovery of a magnetophotoluminescence response in metallofullerene Y3N@C80 triggered by the triplet excited state. In experiments, Y3N@C80 exhibits magnetic field‐dependent (0→±42 T) phosphorescence emission at 4.2 K. Crucially, with increasing magnetic field, the phosphorescence peaks shift to longer wavelengths owing to the Zeeman effect. Further, a nanoring of [9]CPPH is employed to modulate the magnetophotoluminescence response of Y3N@C80 through host−guest interaction. The circularly polarized phosphorescence spectra of Y3N@C80 and Y3N@C80⊂[9]CPPH are investigated to further reveal their magnetophotoluminescence properties using the technique of field‐induced circular polarization (FICPO). These results show that metallofullerene Y3N@C80 with magnetophotoluminescence response has potential applications in spin‐related optical devices and quantum technology.
High Rejection‐Ratio IGZO Ultraviolet Phototransistor via Additional Solution Processed ZnO Absorption Layer
Authors: Ma Jin Hyun , Jeong Jun Hyung , Kang Seong Jae , Park Min Ho , Ha Hyoun Ji , Kim Eojin , You Seungyun , Kim Wonsik , Park Soohyung , Kang Seong Jun 
Published: April 2024

AbstractThe depletion of the ozone layer over the last four decades has increased Earth's exposure to ultraviolet (UV) radiation, posing significant health risks. Indium‐Gallium‐Zinc‐Oxide (IGZO) phototransistors have emerged as promising UV detection candidates, boasting a wide bandgap (>3 eV), low off‐current, high on‐current, and stability. However, previous efforts to enhance the photoresponse of IGZO phototransistors focused on visible light absorption layers, neglecting UV detection. Here, zinc oxide (ZnO) nanoparticles (NPs) as an absorption layer in IGZO TFTs for UV phototransistors are introduced. IGZO/ZnO TFTs exhibit robust photoresponsivity for UV light below 360 nm, showcasing rejection ratios (Ruv / Rvis) of 20 258, 62 261, 193 649, and 401 582 for wavelengths of 360, 340, 320, and 300 nm, respectively. The combination of IGZO's wide bandgap with ZnO NPs proves effective for detecting UV light below 360 nm, even at low incident light intensities (15 µW cm−2). Enhanced photoresponse characteristics are confirmed via ultraviolet photoelectron spectroscopy. This research highlights the potential of IGZO materials for UV phototransistors and introduces a novel perspective on the utilization of an additional absorption layer traditionally employed for the conventional extension into the visible light range.
H3K4me3‐Mediated FOXJ2/SLAMF8 Axis Aggravates Thrombosis and Inflammation in β2GPI/Anti‐β2GPI‐Treated Monocytes
Authors: Tan Yuan , Qiao Jiao , Yang Shuo , Liu Hongchao , Wang Qingchen , Liu Qi , Feng Weimin , Cui Liyan 
Published: April 2024

AbstractAntiphospholipid syndrome (APS) is characterized by thrombus formation, poor pregnancy outcomes, and a proinflammatory response. H3K4me3‐related monocytes activation are key regulators of APS pathogenesis. Therefore, H3K4me3 CUT&Tag and ATAC‐seq are performed to examine the epigenetic profiles. The results indicate that the H3K4me3 signal and chromatin accessibility at the FOXJ2 promoter are enhanced in an in vitro monocyte model by stimulation with β2GPI/anti‐β2GPI, which mimics APS, and decreases after OICR‐9429 administration. Furthermore, FOXJ2 is highly expressed in patients with primary APS (PAPS) and is the highest in patients with triple‐positive antiphospholipid antibodies (aPLs). Mechanistically, FOXJ2 directly binds to the SLAMF8 promoter and activates SLAMF8 transcription. SLAMF8 further interacts with TREM1 to stimulate TLR4/NF‐κB signaling and prohibit autophagy. Knockdown of FOXJ2, SLAMF8, or TREM1 blocks TLR4/NF‐κB and provokes autophagy, subsequently inhibiting the release of inflammatory and thrombotic indicators. A mouse model of vascular APS is established via β2GPI intraperitoneal injection, and the results suggest that OICR‐9429 administration attenuates the inflammatory response and thrombus formation by inactivating FOXJ2/SLAMF8/TREM1 signaling. These findings highlight the overexpression of H3K4me3‐mediated FOXJ2 in APS, which consequently accelerates APS pathogenesis by triggering inflammation and thrombosis via boosting the SLAMF8/TREM1 axis. Therefore, OICR‐9429 is a promising candidate drug for APS therapy.
M2 Tumor‐Associated Macrophages‐Derived Exosomal MALAT1 Promotes Glycolysis and Gastric Cancer Progression
Authors: Wang Yanzheng , Zhang Jiahui , Shi Hui , Wang Maoye , Yu Dan , Fu Min , Qian Yu , Zhang Xiaoxin , Ji Runbi , Wang Shouyu , Gu Jianmei , Zhang Xu 
Published: April 2024

AbstractM2‐polarized tumor‐associated macrophages (M2 TAMs) promote cancer progression. Exosomes mediate cellular communication in the tumor microenvironment (TME). However, the roles of exosomes from M2 TAMs in gastric cancer progression are unclear. Herein, it is reported that M2 TAMs‐derived exosomes induced aerobic glycolysis in gastric cancer cells and enhanced their proliferation, metastasis, and chemoresistance in a glycolysis‐dependent manner. It is identified that MALAT1 (metastasis‐associated lung adenocarcinoma transcript 1) is enriched in M2 TAM exosomes and confirmed that MALAT1 transfer from M2 TAMs to gastric cancer cells via exosomes mediates this effect. Mechanistically, MALAT1 interacted with the δ‐catenin protein and suppressed its ubiquitination and degradation by β‐TRCP. In addition, MALAT1 upregulated HIF‐1α expression by acting as a sponge for miR‐217‐5p. The activation of β‐catenin and HIF‐1α signaling pathways by M2 TAM exosomes collectively led to enhanced aerobic glycolysis in gastric cancer cells. Finally, a dual‐targeted inhibition of MALAT1 in both gastric cancer cells and macrophages by exosome‐mediated delivery of siRNA remarkably suppressed gastric cancer growth and improved chemosensitivity in mouse tumor models. Taken together, these results suggest that M2 TAMs‐derived exosomes promote gastric cancer progression via MALAT1‐mediated regulation of glycolysis. The findings offer a potential target for gastric cancer therapy.
Mesenchymal Stromal Cells Increase the Natural Killer Resistance of Circulating Tumor Cells via Intercellular Signaling of cGAS‐STING‐IFNβ‐HLA
Authors: Yi Ye , Qin Guihui , Yang Hongmei , Jia Hao , Zeng Qibing , Zheng Dejin , Ye Sen , Zhang Zhiming , Liu Tzu‐Ming , Luo Kathy Qian , Deng Chu‐Xia , Xu Ren‐He 
Published: April 2024

AbstractCirculating tumor cells (CTCs) shed from primary tumors must overcome the cytotoxicity of immune cells, particularly natural killer (NK) cells, to cause metastasis. The tumor microenvironment (TME) protects tumor cells from the cytotoxicity of immune cells, which is partially executed by cancer‐associated mesenchymal stromal cells (MSCs). However, the mechanisms by which MSCs influence the NK resistance of CTCs remain poorly understood. This study demonstrates that MSCs enhance the NK resistance of cancer cells in a gap junction‐dependent manner, thereby promoting the survival and metastatic seeding of CTCs in immunocompromised mice. Tumor cells crosstalk with MSCs through an intercellular cGAS‐cGAMP‐STING signaling loop, leading to increased production of interferon‐β (IFNβ) by MSCs. IFNβ reversely enhances the type I IFN (IFN‐I) signaling in tumor cells and hence the expression of human leukocyte antigen class I (HLA‐I) on the cell surface, protecting the tumor cells from NK cytotoxicity. Disruption of this loop reverses NK sensitivity in tumor cells and decreases tumor metastasis. Moreover, there are positive correlations between IFN‐I signaling, HLA‐I expression, and NK tolerance in human tumor samples. Thus, the NK‐resistant signaling loop between tumor cells and MSCs may serve as a novel therapeutic target.
Household food security responses for SNAP participants and nonparticipants
Authors: Wilde Parke E. , Arteaga Irma 
Published: April 2024

AbstractWe investigate the distinct associations between Supplemental Nutrition Assistance Program (SNAP) participation and different experiences of food‐related hardship. Using a generalization of the Rasch model with USDA Economic Research Service 2022 data for 10 adult‐referenced food security survey items, we find evidence of uniform differential item function. The gap in odds of response between the first item (food‐related worry) and the third item (difficulty acquiring balanced meals) was larger for SNAP households than for non‐SNAP households. Similar differences were observed for other survey items. We consider whether SNAP policy or program changes could increase beneficial impacts differentially for particular food‐related hardships.
Linker Mediated Electronic‐State Manipulation of Conjugated Organic Polymers Enabling Highly Efficient Oxygen Reduction
Authors: Ma Rui , Tang Chenglong , Wang Yonglin , Xu Xiaoxue , Wu Mingjie , Cui Xun , Yang Yingkui 
Published: April 2024

AbstractConjugated polymers with tailorable composition and microarchitecture are propitious for modulating catalytic properties and deciphering inherent structure‐performance relationships. Herein, we report a facile linker engineering strategy to manipulate the electronic states of metallophthalocyanine conjugated polymers and uncover the vital role of organic linkers in facilitating electrocatalytic oxygen reduction reaction (ORR). Specifically, a set of cobalt phthalocyanine conjugated polymers (CoPc‐CPs) wrapped onto carbon nanotubes (denoted CNTs@CoPc‐CPs) are judiciously crafted via in situ assembling square‐planar cobalt tetraaminophthalocyanine (CoPc(NH2)4) with different linear aromatic dialdehyde‐based organic linkers in the presence of CNTs. Intriguingly, upon varying the electronic characteristic of organic linkers from terephthalaldehyde (TA) to 2,5‐thiophenedicarboxaldehyde (TDA) and then to thieno/thiophene‐2,5‐dicarboxaldehyde (bTDA), their corresponding CNTs@CoPc‐CPs exhibit gradually improved electrocatalytic ORR performance. More importantly, theoretical calculations reveal that the charge transfer from CoPc units to electron‐withdrawing linkers (i.e., TDA and bTDA) drives the delocalization of Co d‐orbital electrons, thereby downshifting the Co d‐band energy level. Accordingly, the active Co centers with more positive valence state exhibit optimized binding energy toward ORR‐relevant intermediates and thus a balanced adsorption/desorption pathway that endows significant enhancement in electrocatalytic ORR. This work demonstrates a molecular‐level engineering route for rationally designing efficient polymer catalysts and gaining insightful understanding of electrocatalytic mechanisms.
Ratiometric Afterglow Luminescent Imaging of Matrix Metalloproteinase‐2 Activity via an Energy Diversion Process
Authors: Huang Weijing , Zeng Wenhui , Huang Zheng , Fang Daqing , Liu Hong , Feng Min , Mao Liang , Ye Deju 
Published: April 2024

AbstractRatiometric afterglow luminescent (AGL) probes are attractive for in vivo imaging due to their high sensitivity and signal self‐calibration function. However, there are currently few ratiometric AGL probes available for imaging enzymatic activity in living organisms. Here, we present an energy diversion (ED) strategy that enables the design of an enzyme‐activated ratiometric AGL probe (RAG‐RGD) for in vivo afterglow imaging. The ED process provides RAG‐RGD with a radiative transition for an ‘always on’ 520‐nm AGL signal (AGL520) and a cascade three‐step energy transfer (ET) process for an ‘off‐on’ 710‐nm AGL signal (AGL710) in response to a specific enzyme. Using matrix metalloproteinase‐2 (MMP‐2) as an example, RAG‐RGD shows a significant ~11‐fold increase in AGL710/AGL520 toward MMP‐2. This can sensitively detect U87MG brain tumors through ratiometric afterglow imaging of MMP‐2 activity, with a high signal‐to‐background ratio and deep imaging depth. Furthermore, by utilizing the self‐calibration effect of ratiometric imaging, RAG‐RGD demonstrated a strong negative correlation between the AGL710/AGL520 value and the size of orthotopic U87MG tumor, enabling accurate monitoring of orthotopic glioma growth in vivo. This ED process may be applied for the design of other enzyme‐activated ratiometric afterglow probes for sensitive afterglow imaging.
An exhaustive ADDIS principle for online FWER control
Authors: Fischer Lasse , Roig Marta Bofill , Brannath Werner 
Published: April 2024

AbstractIn this paper, we consider online multiple testing with familywise error rate (FWER) control, where the probability of committing at least one type I error will remain under control while testing a possibly infinite sequence of hypotheses over time. Currently, adaptive‐discard (ADDIS) procedures seem to be the most promising online procedures with FWER control in terms of power. Now, our main contribution is a uniform improvement of the ADDIS principle and thus of all ADDIS procedures. This means, the methods we propose reject as least as much hypotheses as ADDIS procedures and in some cases even more, while maintaining FWER control. In addition, we show that there is no other FWER controlling procedure that enlarges the event of rejecting any hypothesis. Finally, we apply the new principle to derive uniform improvements of the ADDIS‐Spending and ADDIS‐Graph.
Nervogenic Acid Derivatives and Phenanthrenes from Liparis nervosa and Their Antimicrobial and Immunosuppressive Activities
Authors: Jiang Hong , Liu Yang , Ren Bo , Lai Yi , Chen Hu‐Lan , Li Li‐Mei 
Published: April 2024

AbstractTwo new nervogenic acid derivatives liparisnervosides Q (1) and R (5), as well as five known nervogenic acid derivatives (2–4, 6, 7) and four phenanthrenes (8–11) were isolated from the whole plant of Liparis nervosa (Thunb. ex A. Murray) Lindl.. Their structures were detremined using extensive spectroscopic techniques, including 1D, 2D NMR, and HR‐ESI‐MS, and acid hydrolysis. Furthermore, their antimicrobial and immunosuppressive activities were evaluated. Nervosine VII (3) exhibited antimicrobial activity against Staphylococcus aureus with an MIC of 62.5 μg/mL and inhibited the proliferation of human T cells with an IC50 value of 9.67±0.96 μM. These findings contribute to our understanding of the potential pharmacological properties of these compounds.