bluuebunny/crossref_metadata_2025_split huggingface dataset:
Evaluation of the effects of premedication on gastroduodenoscopy in cats
Authors: Smith Alison A. , Posner Lysa P. , Goldstein Richard E. , Ludders John W. , Erb Hollis N. , Simpson Kenneth W. , Gleed Robin D. 
Published: January 2006

AbstractObjective—To evaluate the effects of hydromorphone, hydromorphone and glycopyrrolate, medetomidine, and butorphanol premedication on the difficulty and time required to pass an endoscope into the stomach and duodenum of cats anesthetized with ketamine and isoflurane.Design—Randomized complete block crossover study.Animals—8 purpose-bred adult female cats.Procedures—Each cat was premedicated and anesthetized 4 times with an interval of at least 7 days between procedures. Cats were premedicated with hydromorphone, hydromorphone and glycopyrrolate, medetomidine, or butorphanol administered IM. Twenty minutes after premedication, sedation was assessed by use of a subjective ordinal scale. Cats received ketamine administered IM, and 10 minutes later a cuffed orotracheal tube was placed and anesthesia maintained with isoflurane. Cats breathed spontaneously throughout the procedure. When end-tidal isoflurane concentration was stable at 1.4% for 15 minutes, endoscopy was begun. The times required to pass the endoscope through the cardiac and pyloric sphincters were recorded, and the difficulty of endoscope passage was scored by use of a subjective ordinal scale.Results—No significant differences in difficulty or time required to pass the endoscope through the cardiac and pyloric sphincters were found among premedicant groups. Premedication with medetomidine resulted in the greatest degree of sedation and longest time to return to sternal recumbency.Conclusions and Clinical Relevance—Results suggest that hydromorphone, hydromorphone and glycopyrrolate, medetomidine, and butorphanol at the doses tested can be used satisfactorily to premedicate cats prior to general anesthesia for gastroduodenoscopy. (J Am Vet Med Assoc2004;225:540–544)
Association of the PTPN22*R620W polymorphism with autoimmune myasthenia gravis
Authors: Vandiedonck Claire , Capdevielle Claire , Giraud Matthieu , Krumeich Sophie , Jais Jean‐Philippe , Eymard Bruno , Tranchant Christine , Gajdos Philippe , Garchon Henri‐Jean 
Published: January 2006

AbstractObjectiveOur objective was to investigate a role of the intracellular tyrosine phosphatase PTPN22*R620W variant in autoimmune myasthenia gravis (MG), considering disease heterogeneity.MethodsWe used a case–control design, comparing 470 patients and 296 controls, all French whites. Patients were categorized depending on the presence of a thymoma and serum anti‐titin antibodies.ResultsThe 620W risk allele was increased in 293 nonthymoma patients without anti‐titin antibodies (odds ratio, 1.97; 95% confidence interval, 1.32–2.97, p = 0.00059) but not in nonthymoma patients with anti‐titin antibodies or in thymoma patients.InterpretationOur genetic findings strengthen the concept that these groups of patients correspond to etiologically distinct disease entities. Ann Neurol 2006;59:404–407
T118M PMP22 mutation causes partial loss of function and HNPP‐like neuropathy
Authors: Shy Michael E. , Scavina Mena T. , Clark Alisa , Krajewski Karen M. , Li Jun , Kamholz John , Kolodny Edwin , Szigeti Kinga , Fischer Richard A. , Mustafa Saifi Gulam , Scherer Steven S. , Lupski James R. 
Published: January 2006

AbstractObjectiveTo determine the clinical consequences of the PMP22 point mutation, T118M, which has been previously considered to either cause an autosomal recessive form of Charcot‐Marie‐Tooth (CMT) disease or be a benign polymorphism.MethodsWe analyzed patients from five separate kindreds and characterized their peripheral nerve function by clinical and electrophysiological methods.ResultsAll heterozygous patients had clinical and/or electrophysiological features of a neuropathy similar to hereditary neuropathy with liability to pressure palsies (HNPPs). The homozygous patient had a severe axonal neuropathy without features of demyelination.InterpretationThese findings suggest that T118M PMP22 retains some normal PMP22 activity, allowing the formation of compact myelin and normal nerve conduction velocities in the homozygous state. Taken together, these findings suggest that T118M is a pathogenic mutation causing a dominantly inherited form of CMT by a partial loss of PMP22 function. Ann Neurol 2006;59:358–364
Cleavage of cystatin C in the cerebrospinal fluid of patients with multiple sclerosis
Authors: Irani David N. , Anderson Caroline , Gundry Rebekah , Cotter Robert , Moore Stacy , Kerr Douglas A. , McArthur Justin C. , Sacktor Ned , Pardo Carlos A. , Jones Melina , Calabresi Peter A. , Nath Avindra 
Published: January 2006

AbstractObjectiveThe diagnosis of multiple sclerosis (MS) can be challenging because of the lack of a specific diagnostic test. Recent advances in proteomics, however, offer new opportunities for biomarker discovery and the study of disease pathogenesis.MethodsWe analyzed cerebrospinal fluid (CSF) samples from 29 patients with MS or clinically isolated syndromes (CIS), 27 patients with transverse myelitis (TM), 50 patients with human immunodeficiency virus (HIV) infection, and 27 patients with other neurological diseases (ONDs) by surface‐enhanced laser desorption/ionization time‐of‐flight mass spectroscopy.ResultsWe found a unique protein of 12.5kDa that was 100% specific for MS/CIS compared with TM or OND. Low levels of this protein were found in some patients with HIV infection. Tandem mass spectroscopy of a tryptic digest of this 12.5kDa protein identified it as a cleavage product of full‐length cystatin C (13.4kDa), an important inhibitor of cysteine proteases including the cathepsins. Although total cystatin C levels in the MS patients was not different compared with controls, the patients with the highest 12.5/13.4 peak ratios also had the greatest cathepsin B inhibitory activity.InterpretationThis suggests that cleavage of cystatin C may be an adaptive host response and may identify a subgroup of patients with MS. Ann Neurol 2006;59:237–247
Crystal Structures and Magnetic Properties of Mixed Iridium—Ruthenium Triple Perovskites. Part 2. Ba3MRuIrO9 (M: Li, Na, Mg, Ni, Zn, Bi, In).
Authors: Lufaso Michael W. , zur Loye Hans‐Conrad 
Published: January 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access the actual ChemInform Abstract, please click on HTML or PDF.
Synthesis and Characterization of a New Layered Zinc Phosphite (NH4) [{Zn(H2O)4}0.5Zn2 (HPO3)3].
Authors: Zeng Qing‐Xin , Ke Ren‐Rui , Xiang Yong , Zhang Xiang‐Wen 
Published: January 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access the actual ChemInform Abstract, please click on HTML or PDF.
Chiral Oxazoline‐1,3‐dithianes: New Effective Nitrogen—Sulfur Donating Ligands in Asymmetric Catalysis.
Authors: Capito Elena , Bernardi Luca , Comes‐Franchini Mauro , Fini Francesco , Fochi Mariafrancesca , Pollicino Salvatore , Ricci Alfredo 
Published: January 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access the actual ChemInform Abstract, please click on HTML or PDF.
Reactions of Complex Ligands. Part 107. Quinoid BINOL‐Type Compounds as a Novel Class of Chiral Ligands.
Authors: Minatti Ana , Doetz Karl Heinz 
Published: January 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access the actual ChemInform Abstract, please click on HTML or PDF.
Anilinosilanes/TBAF Catalyst: Mild and Powerful Agent for the Silylation of Sterically Hindered Alcohols.
Authors: Iida Akira , Horii Atsushi , Misaki Tomonori , Tanabe Yoo 
Published: January 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access the actual ChemInform Abstract, please click on HTML or PDF.
Synthesis of Bacterial Metabolites of Polycyclic Aromatic Hydrocarbons: Benzochromenones, o‐Carboxyvinylnaphthoates, and o‐Substituted Aryl‐α‐oxobutenoates.
Authors: Keum Young‐Soo , Seo Jong‐Su , Li Qing X. 
Published: January 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access the actual ChemInform Abstract, please click on HTML or PDF.
Zinc Oxide (ZnO) as a New, Highly Efficient, and Reusable Catalyst for Acylation of Alcohols, Phenols and Amines under Solvent Free Conditions.
Authors: Sarvari Mona Hosseini , Sharghi Hashem 
Published: January 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access the actual ChemInform Abstract, please click on HTML or PDF.
Trimethylsilyl Trifluoromethanesulfonate Catalyzed One‐Pot Method for the Conversion of Aldehydes to Homoallyl Ethers in an Ionic Liquid.
Authors: Anzalone Peter W. , Mohan Ram S. 
Published: January 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access the actual ChemInform Abstract, please click on HTML or PDF.
A Green Procedure for the Synthesis of Cinnamate Esters Using Aliquat®336.
Authors: Mahapatra Tanusri , Patra Amarendra , Mitra Alok Kumar 
Published: January 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access the actual ChemInform Abstract, please click on HTML or PDF.
Enantioselective Construction of Stereogenic Quaternary Centers via Rh‐Catalyzed Asymmetric Addition of Alkenylboronic Acids to α,β‐Unsaturated Pyridylsulfones.
Authors: Mauleon Pablo , Carretero Juan C. 
Published: January 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access the actual ChemInform Abstract, please click on HTML or PDF.
One‐Pot Method for Stereoselective Cyclopropanation of Electron‐Deficient Olefins with Methyl Bromoacetate and Phenacyl Bromide in the Presence of Triphenylarsine.
Authors: Ren Zhongjiao , Cao Weiguo , Ding Weiyu , Wang Yu 
Published: January 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access the actual ChemInform Abstract, please click on HTML or PDF.
The First Buckybowl Aryne. Corannulyne: A Nonplanar Benzyne.
Authors: Sygula Andrzej , Sygula Renata , Rabideau Peter W. 
Published: January 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access the actual ChemInform Abstract, please click on HTML or PDF.
Microwave‐Assisted Addition of Pyrroles to Electron‐Deficient Olefins: A Rapid Entry to C‐Alkyl Pyrroles.
Authors: Zhan Zhuang‐Ping , Yang Wen‐Zhen , Yang Rui‐Feng 
Published: January 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access the actual ChemInform Abstract, please click on HTML or PDF.
Preparation of RCM Substrates for Azepinoindole Synthesis: Reductive Amination versus Tetrahydro‐γ‐carboline Formation.
Authors: Bennasar M.‐Lluisa , Zulaica Ester , Alonso Sandra 
Published: January 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access the actual ChemInform Abstract, please click on HTML or PDF.
Ring‐Opening Reactions of Cyclopropanes. Part 8. Nitrosation of Donor—Acceptor Cyclopropanes.
Authors: Cermola Flavio , Di Gioia Lucrezia , Graziano Maria Liliana , Iesce Maria Rosaria 
Published: January 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access the actual ChemInform Abstract, please click on HTML or PDF.
Synthesis and Caspase‐3 Inhibitory Activity of 8‐Sulfonyl‐1,3‐dioxo‐2,3‐dihydro‐1H‐pyrrolo[3,4‐c]quinolines.
Authors: Kravchenko Dmitri V. , Kysil Volodymyr M. , Tkachenko Sergey E. , Maliarchouk Sergey , Okun Ilya M. , Ivachtchenko Alexandre V. 
Published: January 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access the actual ChemInform Abstract, please click on HTML or PDF.
Multicomponent Condensation of Aliphatic Amines with Formaldehyde and Hydrogen Sulfide.
Authors: Khafizova S. R. , Akhmetova V. R. , Korzhova L. F. , Tyumkina T. V. , Nadyrgulova G. R. , Kunakova R. V. , Kruglov E. A. , Dzhemilev U. M. 
Published: January 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access the actual ChemInform Abstract, please click on HTML or PDF.
Synthesis of 9‐Thia‐3,7‐diazabicyclo[3.3.1]nonane 9,9‐Dioxides.
Authors: Vlasova L. I. , Baibulatova N. Z. , Latypova D. R. , Yunusov M. S. , Dokichev V. A. , Tomilov Yu. V. 
Published: January 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access the actual ChemInform Abstract, please click on HTML or PDF.
Phosphorylation of 1,4‐Bis(hydroxymethyl)benzene.
Authors: Rasadkina E. N. , Slitikov P. V. , Stash A. I. , Nifant'ev E. E. 
Published: January 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access the actual ChemInform Abstract, please click on HTML or PDF.
Total Synthesis of (.+‐.)‐Ceratopicanol: Application of Pd‐Catalyzed Enediyne Cycloreduction.
Authors: Oh Chang Ho , Rhim Chul Yun , Kim Mira , Park Dai In , Gupta Aruna Kumar 
Published: January 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access the actual ChemInform Abstract, please click on HTML or PDF.
Chemical Optimization of Artificial Metalloenzymes Based on the Biotin‐Avidin Technology: (S)‐Selective and Solvent‐Tolerant Hydrogenation Catalysts via the Introduction of Chiral Amino Acid Spacers.
Authors: Skander Myriem , Malan Christophe , Ivanova Anita , Ward Thomas R. 
Published: January 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access the actual ChemInform Abstract, please click on HTML or PDF.
Synthesis of Ring‐A‐Substituted Tryptophan by a Palladium‐Catalyzed Heteroannulation Reaction.
Authors: Jia Yanxing , Zhu Jieping 
Published: January 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access the actual ChemInform Abstract, please click on HTML or PDF.
Four New Phenones (I)‐(III) from the Cortexes of Polygala tenuifolia.
Authors: Jiang Yong , Tu Pengfei 
Published: January 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access the actual ChemInform Abstract, please click on HTML or PDF.
Biflavone Glucosides from Ginkgo biloba Yellow Leaves.
Authors: Hyun Sook Kyung , Kang Sam Sik , Son Kun Ho , Chung Hae Young , Choi Jae Sue 
Published: January 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access the actual ChemInform Abstract, please click on HTML or PDF.
New Plastoquinones Isolated from the Brown Alga, Sargassum micracanthum.
Authors: Mori Jun , Iwashima Makoto , Wakasugi Hiroko , Saito Haruo , Matsunaga Takayuki , Ogasawara Masaru , Takahashi Satoshi , Suzuki Hideyo , Hayashi Toshimitsu 
Published: January 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access the actual ChemInform Abstract, please click on HTML or PDF.
FR258900, a Novel Glycogen Phosphorylase Inhibitor Isolated from Fungus No.138354. Part 1. Taxonomy, Fermentation, Isolation and Biological Activities.
Authors: Furukawa Shigetada , Tsurumi Yasuhisa , Murakami Kana , Nakanishi Tomoko , Ohsumi Keisuke , Hashimoto Michizane , Nishikawa Motoaki , Takase Shigehiro , Nakayama Osamu , Hino Motohiro 
Published: January 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access the actual ChemInform Abstract, please click on HTML or PDF.
Synthesis and Properties of Isocannabinoid and Cholesterol Derivatized Rhamnosurfactants: Application to Liposomal Targeting of Keratinocytes and Skin.
Authors: Barragan‐Montero Veronique , Winum Jean‐Yves , Moles Jean‐Pierre , Juan Emmanuelle , Clavel Caroline , Montero Jean‐Louis 
Published: January 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access the actual ChemInform Abstract, please click on HTML or PDF.
Preparation of 3‐Spirocyclic Indolin‐2‐ones as Ligands for the ORL‐1 Receptor.
Authors: Bignan Gilles C. , Battista Kathleen , Connolly Peter J. , Orsini Michael J. , Liu Jingchun , Middleton Steven A. , Reitz Allen B. 
Published: January 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access the actual ChemInform Abstract, please click on HTML or PDF.
Collective Spin and Charge Excitations in (Sr,La)14‐xCaxCu24O41 Quantum Spin Ladders
Authors: Gozar A. , Blumberg G. 
Published: January 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access the actual ChemInform Abstract, please click on HTML or PDF.
Selectfluor (F‐TEDA‐BF4) as a Versatile Mediator or Catalyst in Organic Chemistry
Authors: Stavber Stojan , Zupan Marko 
Published: January 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access the actual ChemInform Abstract, please click on HTML or PDF.
Responses of large volcanic eruptions in the instrumental and documentary climatic data over Central Europe
Authors: Písek Jan , Brázdil Rudolf 
Published: January 2006

AbstractResponses of large volcanic eruptions in selected long temperature series from Austria, the Czech Republic and Germany as well as in three global radiation series in Central Europe are studied. In the example of seven large tropical eruptions (Krakatau 1883; Pelée, Soufriére and Santa María 1902; Agung, 1963; El Chichón, 1982; Mt Pinatubo, 1991) it has been demonstrated that volcanic signal in regional series is not so strongly expressed as in the hemispheric scale owing to different local effects and circulation patterns. This is also valid in the case of two further discussed eruptions of Tambora (1815) and Katmai (1912). The responses of eruptions in areas closer to Central Europe such as Iceland or Italy are more important. In nine analysed cases with VEI = 4–5 with a single exception of the Hekla eruption (1917), cold seasons were observed to follow the eruption. Responses to the Lakagígar eruption (1783) of Iceland with important impacts are also discussed in detail. Moreover, correlation between temperatures (annual and winter half‐year series) and NAOI is prevailingly smaller for the period following eruptions than in the period preceding eruptions. The importance of documentary evidence as a valuable source of the information about the impacts of volcanic eruptions is demonstrated. Copyright © 2006 Royal Meteorological Society.
Morphological and mechanical properties of carbon nanotube/polymer composites via melt compounding
Authors: Dondero William E. , Gorga Russell E. 
Published: January 2006

AbstractThe mechanical properties and morphology of multiwall carbon nanotube (MWNT)/polypropylene (PP) nanocomposites were studied as a function of nanotube orientation and concentration. Through melt mixing followed by melt drawing, using a twin screw mini‐extruder with a specially designed winding apparatus, the dispersion and orientation of MWNTs was optimized in PP. Tensile tests showed a 32% increase in toughness for a 0.25 wt % MWNT in PP (over pure PP). Moreover, modulus increased by 138% with 0.25 wt % MWNTs. Transmission electron microscopy and scanning electron microscopy demonstrated qualitative nanotube dispersion and orientation. Wide angle X‐ray diffraction was used to study crystal morphology and orientation by calculating the Herman's orientation factor for the composites as function of nanotube loading and orientation. The addition of nanotubes to oriented samples causes the crystalline morphology to shift from α and mesophase to only α phase. Furthermore, the addition of nanotubes (without orientation) was found to cause isotropization of the PP crystal, and drawing was shown to improve crystal orientation through the orientation factor. In addition, differential scanning caloriometry qualitatively revealed little change in overall crystallinity. In conclusion, this work has shown that melt mixing coupled with melt drawing has yielded MWNT/PP composites with a unique combination of strength and toughness suitable for advanced fiber applications, such as smart fibers and high‐performance fabrics. © 2006 Wiley Periodicals, Inc. J Polym Sci Part B: Polym Phys 44: 864–878, 2006
A Strategy for the Identification of Canonical and Non‐canonical MHC I‐binding Epitopes Using an ANN‐based Epitope Prediction Algorithm
Authors: Filter Matthias , Eichler‐Mertens Mathias , Bredenbeck Anne , Losch Florian O. , Sharav Tumenjargal , Givehchi Alireza , Walden Peter , Wrede Paul 
Published: January 2006

AbstractSmall peptides bound by Major Histocompatibility Complex (MHC) class I molecules and recognized in this context by the T‐cell receptor of CD8+ T cells are known as T‐cell epitopes and are of extraordinary importance for the development of new vaccines against cancer and viral infections. Several algorithms predicting a peptide's binding capability to a given MHC class I molecule are currently available and have been successfully applied in the identification of new T‐cell epitopes within proteins. Most of these newly identified epitopes obey to the empirically determined anchor residue patterns that are specific for the different MHC I alleles. However, in recent studies an increasing number of weakly binding T‐cell epitopes could be identified that do not fit to these canonical amino acid patterns. Therefore there is a need for new prediction algorithms improving the prediction accuracy for weakly binding epitopes that are biologically relevant as they are presented by, e.g. antigen presenting cells.