bluuebunny/crossref_metadata_2025_split huggingface dataset:
EEG sleep variables of rheumatoid arthritis patients
Authors: Crosby Leanna J. 
Published: February 2007

AbstractIndividuals with rheumatoid arthritis (RA) frequently complain of poor sleep quality and quantity. The purpose of this research was to determine the electroencephalographic (EEG) sleep variables of rheumatoid arthritis patients at different stages of RA disease activity and to compare the EEG sleep variables of RA patients to an age‐ and gender‐matched control group. The subjects included 15 RA patients (11 female and four male) and 12 control subjects (nine female and three male). The sleep data of five RA patients who were in flare were compared with the sleep data of five age‐ and gender‐matched control subjects. Sleep data of ten RA patients who were in a state of nonflare were compared to seven age‐ and gender‐matched control subjects. Data analysis indicated that RA patients in flare had statistically significant lower sleep efficiency scores and had spent more time awake during the night when compared to control subjects. Both RA flare and nonflare groups demonstrated fragmented sleep patterns due to frequent awakenings and frequent sleep stage changes.
Treatment of sleep disturbance in rheumatoid arthritis: A single‐subject experiment
Authors: Wegener Stephen T. 
Published: February 2007

AbstractSleep disturbances are a relatively frequent complication of rheumatoid arthritis (RA). This study investigated the effectiveness of behavioral strategies for the control of sleep disturbances in a woman with RA. A single‐subject experimental design with a reversal phase was used to evaluate the efficacy of the treatment. Sleep parameters, pain, and mood were measured using daily diaries and home monitoring. A combined treatment of stimulus control and relaxation training was most effective in improving sleep parameters and mood when compared with baseline, treatment withdrawal, and sleep hygiene education phases. Treatment gains were maintained at 8‐week follow‐up.
AHPA teaching slide collection, 2nd edition: A review
Authors: Hazelwood Susan E. , Rodon Carole M. , Pressly Thomas A. , Long John H. , Smith Elaine I. , Minor Marian A. , Virgen Lavona L. 
Published: February 2007

AbstractThe Arthritis Health Professions Association (AHPA) first marketed an arthritis teaching slide collection in 1980. Recent changes in rheumatic disease diagnosis and management made it necessary to update this collection. A second edition premiered in June 1988 at the AHPA National Scientific Meeting. This revised collection totals 293 slides, with nearly 100 new slides and redesign of others. The slides are a mixture of photographs, text, medical illustrations, cartoons, and computer‐generated graphics. Rheumatic diseases covered by the collection include rheumatoid arthritis, osteoarthri‐tis, Sjogren's syndrome, juvenile rheumatoid arthritis, ankylosing spondylitis, psoriatic arthritis, Reiter's syndrome, systemic lupus erythematosus, systemic sclerosis, gout, polymyositis/dermatomyo‐sitis, polymyalgia rheumatica, fibrositis, osteoporosis, and a few miscellaneous conditions. The collection is organized into six major color‐coded sections. The first four sections provide an overview of the rheumatic diseases (nine slides), rheumatic disease clinical manifestations (113 slides), joint anatomy (four slides), and pathophysiology (seven slides). The last two sections cover disease assessment (38 slides) and management (117 slides), em‐phasizing the role of health professionals. There are also five introductory slides that highlight the AHPA organization.
Intraarticular corticosteroid injections: Should we rest the joints?
Authors: Chatham Winn , Williams Gwen , Moreland Larry , Parker Julia W. , Ross Cindy , Alarcon Sylvia G. , Alarcon Graciela S. 
Published: February 2007

AbstractTo prevent damage in injected joints, it has been our policy to rest them for 48 hours. To test this assertion we randomized 30 rheumatoid arthritis (RA) patients (rest, no‐rest). Results in 28 patients (63 joints: 27 rest and 36 no‐rest) are presented. Joint evaluation was performed at baseline and at 48 hours (pain/tenderness, swelling and range of motion). Two analyses were conducted, the first included all joints, and the second only joint pairs. In both cases measurements at 48 hours were comparable for the rest and no rest group for both upper and lower extremity joints (pain/tenderness/swelling and range of motion). At a later follow up (average 10 months) there were no differences in any of the parameters examined. Our study suggests that rest is not essential for intraarticular corticosteroids to be beneficial, at least in an inpatient setting. The applicability of our data to an outpatient population remains to be determined.
Adherence with treatment regimens among adult rheumatoid arthritis patients: Current status and future directions
Authors: Bradley Laurence A. 
Published: February 2007

AbstractThis paper reviews the literature concerning adult rheumatoid arthritis (RA) patients' adherence with medication regimens, home exercise, splint usage, and self‐management of pain. There are few reliable data regarding the prevalence of adherence problems or the attributes of patients, health‐care providers, and environments that may influence adherence. In addition, little effort has been devoted to the development of interventions that may enhance adherence. Future investigators should attend to (1) the development of reliable and valid measures of adherence; (2) longitudinal studies of changes in adherence as a function of disease activity, treatment methods, and third‐party reimbursements for services; (3j observational studies of patient–provider interactions and their influence on adherence; and (4) interventions to enhance adherence that are based on a self‐regulation model.
Computerized three‐dimensional analysis of the heart and great vessels in normal and holoprosencephalic human embryos
Authors: Yamada Shigehito , Itoh Hitoshi , Uwabe Chigako , Fujihara Sachiko , Nishibori Chiaki , Wada Masaaki , Fujii Shingo , Shiota Kohei 
Published: February 2007

AbstractThe developing heart and great vessels undergo drastic morphogenetic changes during the embryonic period. To analyze the normal and abnormal development of these organs, it is essential to visualize their structures in three and four dimensions, including the changes occurring with time. We have reconstructed the luminal structure of the hearts and great vessels of staged human embryos from serial histological sections to demonstrate their sequential morphological changes in three dimensions. The detailed structures of the embryonic heart and major arteries in normal and holoprosencephalic (HPE) human embryos could be reconstructed and visualized, and anatomical structures were analyzed using 3D images. By 3D analysis, cardiac anomalies such as double‐outlet right ventricle and malrotation of the heart tube were identified in HPE embryos, which were not easily diagnosed by histological observation. Reconstruction and analysis of 3D images are useful for the study of anatomical structures of developing embryos and for identifying their abnormalities. Anat Rec, 2007. © 2007 Wiley‐Liss, Inc.
Cortical connections of the middle temporal and the middle temporal crescent visual areas in prosimian galagos (Otolemur garnetti)
Authors: Kaskan Peter M. , Kaas Jon H. 
Published: February 2007

AbstractWhile considerable progress has been made in understanding the organization of visual cortex in monkeys, less is known about the visual systems of prosimians. The middle temporal visual area (MT), an area involved in motion perception, is common to all primates. We placed injections of tracers in MT and just caudal to MT in cortex expected to be the MT crescent (MTc), an area previously identified in monkeys but not in prosimians. We analyzed the patterns of projections in sections of the flattened cortex and used sections stained for cytochrome oxidase (CO) and myelin to identify the borders of MT, MTc, middle superior temporal (MST), superior temporal sulcus (FST), and V1 and V2 and to identify possible subdivisions of these areas. As in owl monkeys, MTc is a belt around most of MT that consists of a single row of CO‐dense patches in a CO‐light surround. Injections placed in MT revealed connections with V1, V2, V3, FST, MST, MTc, dorsomedial, dorsolateral (DL), posterior parietal cortex, and inferotemporal (IT) cortex. Injections localized to MTc displayed a slightly different pattern of connections with more involvement of DL and IT cortex, though other aspects, including patchy connections with V1 and V2, were similar to MT connections. The results indicate that prosimian galagos have an MT area with connection patterns that are similar to those in New and Old World monkeys. The MTc, initially described in owl monkeys, is present in galagos and is likely to be a common component of primate visual cortex. Anat Rec 2007. © 2007 Wiley‐Liss, Inc.
A re‐evaluation of gelsolin at ectoplasmic specializations in sertoli cells: The influence of serum in blocking buffers on staining patterns
Authors: Guttman Julian A. , Vaid Kuljeet S. , Vogl A. Wayne 
Published: February 2007

AbstractIn this study, we test the hypothesis that gelsolin immunolocalized in actin filament‐rich ectoplasmic specializations may be exogenous gelsolin present in normal serum used in blocking buffers, and that binds to the intercellular adhesion plaques during tissue processing. Fixed frozen sections of rat and rabbit testis were pre‐treated with standard blocking buffers containing 5% normal goat serum (NGS) and then incubated with anti‐gelsolin antibodies in the presence of 1% NGS. Other sections were treated in a similar fashion, but in buffers not containing NGS. Sections were then labeled with secondary antibody conjugated to a fluorochrome. Localized staining at ectoplasmic specializations occurred only in sections treated with NGS. The only positive staining in sections not treated with NGS was associated with seminiferous tubule walls and blood vessels in rabbit tissue. The antibodies reacted with a single band at the appropriate molecular weight for gelsolin on immunoblots of NGS, but did not react on immunoblots of testis or seminiferous epithelium. We conclude that gelsolin localized at ectoplasmic specializations using current commercially available antibodies is a result of non‐specific binding to the fixed tissues of gelsolin present in blocking buffers. Anat Rec 2007. © 2007 Wiley‐Liss, Inc.
The pH dependence of the sensitized sheep cell reaction of sera from patients with rheumatoid arthritis
Authors: Heimer Ralph , Federico Olga , Freyberg Richard H. 
Published: February 2007

AbstractAn effect of pH on the agglutinating activity of rheumatoid sera was demonstrated in the sensitized sheep cell test and the potentiated sensitized sheep cell test. Although the use of a buffering system did not change the incidence of positive tests, it did increase the titer of some sera. The studies suggest that inhibition of the agglutination system by some chemicals may be a function of pH, and that free amino groups may be essential for agglutination.Un effecto de pH super le activitate agglutinante de seros rheumatoide esseva demonstrate in le test a sensibilisate cellulas ovin, simple e potentiate. Ben que le uso de un systema de tamponage non alterava le frequentia de resultatos positive, illo augmentava nonobstante le titro de certe seros. Le studios suggere que le inhibition del systema agglutinatori per un substantia chimic es forsan un function de pH e que libere amino‐gruppos es essential pro le agglutination.
Effect of desacetylmethylcolchicine (Colcemide) in acute gouty arthritis
Authors: Neustadt David H. 
Published: February 2007

AbstractDesacetylmethylcolchicine (Colcemide) compared favorably with colchicine in the treatment of acute gout in 17 patients. Although gastrointestinal symptoms were avoided, other more serious undesirable effects such as bone‐marrow depression and alopecia are cited.Disacetylmethylcolchicina (Colcemide) esseva favorabile in comparation con colchicina in le tractamento de gutta acute in 17 patientes. Ben que symptomas gastrointestinal esseva evitate, altere plus serie effectos adverse, per exemplo depression del medulla ossee e alopecia, es citate.
Manganese in the therapy of disseminated lupus erythematosus
Authors: Redleaf Paul D. 
Published: February 2007

AbstractOn the basis of a reported relationship between manganese depletion and the hydralazine syndrome, the possible therapeutic role of this metal in systemic lupus erythematosus was studied. Manganese glycerophosphate was administered to six patients with the latter disease without favorable effects, suggesting that the hydralazine syndrome and systemic lupus erythematosus have different pathogenic mechanisms.Super le base del reportate relation inter le depletion de manganese e le syndrome de hydralazina, le possibile rolo therapeutic de iste metallo in systemic lupus erythematose esseva studiate. Glycerophosphato de manganese esseva administrate a sex patientes con le morbo mentionate. Le absentia de effectos favorabile suggere que le syndrome de hydralazina e systemic lupus erythematose es governate per differente mechanismos pathogenic.
The incidence of the L.E. cell phenomenon in patients with rheumatoid arthritis. (A two‐year study)
Authors: Sigler John W. , Monto Raymond W. , Ensign Dwight C. , Wilson George M. , Rebuck John W. , Lovett John D. 
Published: February 2007

AbstractAdditional data concerning the presence of the L.E. factor in patients with rheumatoid arthritis is presented. Of 45 patients, 11 (24 per cent) had positive L.E. tests at some time during their period of study. Two such patients developed clinical manifestations compatible with systemic lupus erythematosus.Datos additional in re le presentia del factor lupo‐erythematose (L.E.) in patientes con arthritis rheumatoide es presentate. In 11 ex 45 patientes (i.e. in 24%), le test a L.E. esseva positive a un tempore o un altere durante le periodo de lor studio. Duo tal patientes disveloppava manifestationes clinic compatibile con systemic lupus erythematose.
Serum glutamic oxalacetic transaminase in rheumatoid arthritis and certain rheumatoid musculoskeletal disorders
Authors: Barr James H. , Stolzer Bertrand L. , Eisenbeis Carl H. , Kurtz John E. , Margolis H. M. 
Published: February 2007

AbstractSerum glutamic oxalacetic transaminase levels were determined and compared in rheumatoid and nonrheumatoid subjects. The results indicate that tests for this enzyme would be of little value in establishing the presence or absence of rheumatoid disease.Le nivellos de transaminase glutamic‐oxalacetic in le sems de subjectos rheumatoide e non‐rheumatoide esseva determinate e comparate. Le resultatos indica que tests pro iste enzyma esseren de pauc valor establir le presentin o le absentia de morbo rheumatoide.
The role of the kidney in the pathogenesis and treatment of gout
Authors: Wyngaarden James B. 
Published: February 2007

AbstractThe author presents a comprehensive review of experimental observations and changing concepts concerning the relationship of renal function to gout. Recent knowledge of the role of the kidney in the pathogenesis and treatment of this disease has been summarized. Topics that are discussed include urate excretion in normal and gouty individuals, renal dysfunction in patients with gout, primary renal gout and the pharmacology of uricosuric agents. Le autor presenta un revista comprehensive del observationes experimental e del cambiante conceptos in re le relation inter function renal e gutta. Le cognoscentias currente in re le rolo del ren in le pathogenese e le tractamento de iste morbo es summarisate. Le themas discutite include le excretion de urato in individuos normal e guttose, le dysfunction renal in guttosos, primari gutta renal, e le pharmacologia de agentes uricosuric.
Regulatory factors in hormonally induced polyarteritis nodosa in rats
Authors: Perry James C. , Perry Nancy B. 
Published: February 2007

AbstractDiffuse polyarteritis was induced in rats by the long‐term administration of estrogen and follicle‐stimulating hormones. Tumorous changes also appeared in the anterior pituitary gland which were associated with cortical adenoma of the adrenal. It was postulated that mineralo‐corticoid secretions of the latter played a role in the pathogenesis of the vasculitis.Polyarteritis nodose esseva inducite in rattos per le administration a longe vista de estrogeno e hormones folliculo‐stimu‐lante. Alterationes tumorose appareva etiam in le glandula pituitari anterior, associate con adenoma cortical del glandula adrenal. Esseva postulate que secretiones mineralocorticoide del glandula adrenal habeva un rolo in le pathogenese del vasculitis.
Observations concerning positive serologic reactions for rheumatoid factor in certain patients with sarcoidosis and other hyperglobulinemic states
Authors: Kunkel Henry G. , Simon Harold J. , Fudenberg Hugh 
Published: February 2007

AbstractPositive latex fixation tests were observed in relation to sarcoidosis, kala azar and liver disease without concomitant rheumatoid arthritis. Ultracentrifugation of sera from these patients revealed the presence of a heavy gamma globulin resembling rheumatoid factor. Amboceptor‐sensitized sheep cell tests were uniformly negative except in the one case of liver disease.
Observations on the course and treatment of systemic lupus erythematosus
Authors: Ziff Morris , Esserman Paul , McEwen Currier 
Published: February 2007

AbstractLong‐term clinical and laboratory studies of 24 cases of systemic lupus erythematosus provide additional information concerning the nature of this polysymptomatic disease. Positive rheumatoid serologic tests were observed in 28 per cent of patients tested. Antimalarial drugs seemed to benefit most patients.
The relationship to rheumatoid arthritis of its so‐called variants
Authors: McEwen Currier , Ziff Morris , Carmel Philip , Ditata Domenick , Tanner Martin 
Published: February 2007

AbstractThe principal manifestations of certain syndromes presumed to be variants of rheumatoid arthritis are reviewed and the results of serologic studies presented. The entities investigated were anky‐losing spondylitis, Still's disease, psoriatic arthritis, the arthritis of ulcerative colitis and Reiter's syndrome. Serologic observations suggested that Still's syndrome is truly juvenile rheumatoid arthritis but that the other variants may be separate diseases.
Synovial fluid hyaluronate in rheumatoid arthritis
Authors: Hamerman David , Schuster Hilda 
Published: February 2007

AbstractBy several analytic methods, the hyaluronate hexosamine concentration of synovial fluid was found low in the joint effusions of rheumatoid arthritis in comparison to normal synovial fluid. An increase in nonhyaluronate hexosamine was observed in rheumatoid synovial fluid of increased volume. Relative viscosity measurements after equilibrating hexosamine Concentration by dilution revealed few differences between rheumatoid and normal fluid.
Anti‐cytoplasmic factors in the sera of patients with systemic lupus erythematosus and certain other diseases
Authors: Deicher Helmuth R. G. , Holman Halsted R. , Kunkel Henry G. 
Published: February 2007

AbstractComplement fixation reactions were obtained with the use of cytoplasmic cellular constituents and sera from patients with S.L.E. as well as sera from cases of primary biliary cirrhosis and Sjogren's syndrome. These reactions were independent of those involving nuclear components. The serum proteins responsible for the described reactions were shown to be gamma globulins. Evidence was produced that different constituents of microsomes were responsible for the reactions in the different diseases.
The precipitin reaction between rheumatoid factors and gamma globulin: Studies by double diffusion in agar
Authors: Franklin E. C. 
Published: February 2007

AbstractBy means of modified double diffusion technics in agar it has been possible to confirm previous findings that the rheumatoid factor is a 19 S gamma globulin which reacts with a fraction related to 7 S gamma globulin. With these technics, additional evidence of the existence of more than one rheumatoid factor in patients with rheumatoid arthritis has been obtained. These results suggest a close relationship of the rheumatoid factors to serologically active proteins in other disease states.
A study of some “acute phase reactants” in rheumatic diseases
Authors: Decker Barry , Mc Guckin Warren F. , Mc Kenzie Bernard F. , Slocumb Charles H. 
Published: February 2007

AbstractRepresentative “acute phase reactants” and a “clinical index” of synovial in flammation were determined in patients with various rheumatic diseases. The serum hexose‐protein (PR) ratio, serum protein‐bound hexose and seromucoid determinations were consistently found a more reliable indication of the extent of systemic inflammation than the other tests studied. Systemic inflammation, measured by “acute phase reactants,” paralleled the clinically determined synovial reaction only in patients with rheumatoid arthritis.
Sjogren's syndrome I. Serologic reactions in patients with Sjogren's syndrome with and without rheumatoid arthritis
Authors: Bloch K. J. , Wohl M. J. , Ship I. I. , Oglesby R. B. 
Published: February 2007

AbstractSera from 21 patients with Sjogren's syndrome with and without rheumatoid arthritis were examined. Hypergammaglobulinemia occurred in 71 per cent, the bentonite flocculation test was positive in 95 per cent and sensitized sheep cell agglutination test in 90 per cent of the entire group and in 75 per cent of patients with Sjogren's syndrome without joint involvement. Antinuclear antibody was present in 71 per cent and L.E. cells in 10 per cent. The direct Coombs' test was positive in 25 per cent and thyroglobulin antibodies were found in 14 per cent. Compared to rheumatoid arthritis patients without Sjogren's syndrome, patients in this series were distinguished by an unusually active immunologic response.
Effect of an anabolic agent (Nilevar) on nitrogen and mineral metabolism in two patients with rheumatoid disease
Authors: Habbis Jean , Blechman Wilbub , Young Nelson , Malm Ole , Vaughan John H. 
Published: February 2007

AbstractAn androgenic steroid, chemically modified to have less masculinizing activity per unit anabolic activity, was studied in two patients with rheumatoid arthritis. In one patient, the anabolic steroid reversed both the nitrogen loss secondary to disease activity and the nitrogen loss secondary to corticosteroid treatment. In the other patient the effectiveness of the anabolic agent in promoting calcium retention was demonstrated.
Some carbohydrates of synovial fluid
Authors: Smith Joe Ed , Crowley George T. , Giles Robert B. 
Published: February 2007

AbstractSynovial fluids from a group of patients without clinical joint disease and from a group of patients with joint disease have been analyzed for several carbohydrate components. One patient is reported who has an increased amount of galatosamine in the synovial fluid but not in the serum. These findings are discussed.
The entrance of glucose and other sugars into joints
Authors: Ropes Marian W. , Muller Alex F. , Bauer Walter 
Published: February 2007

AbstractEntrance of glucose into joints was determined in calves and in patients with joint disease. In calves under two weeks, entrance was rapid; delayed in older calves. In patients with joint disease there was delay in appearance and slow subsequent entrance, more marked with greater severity of disease. The rate with galactose was the same; that with pentoses and methylated glucoses usually more rapid. The nature of the mechanism of transport is not apparent.