bluuebunny/crossref_metadata_2025_split huggingface dataset:
Aqueous N‐Heterocyclization of Primary Amines and Hydrazines with Dihalides: Microwave‐Assisted Syntheses of N‐Azacycloalkanes, Isoindole, Pyrazole, Pyrazolidine, and Phthalazine Derivatives.
Authors: Ju Yuhong , Varma Rajender S. 
Published: April 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
New Synthesis of 3‐Arylpyrrolines.
Authors: Chang Meng‐Yang , Pai Chun‐Li , Kung Yung‐Hua 
Published: April 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Pyrrolate‐Catalyzed Conjugate Addition of Pyrrole to Electron‐Deficient Alkenes.
Authors: Richardson Robert D. , Hernandez‐Juan Felix A. , Dixon Darren J. 
Published: April 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
An Efficient Two‐Step Synthesis of 3‐Allylindoles
Authors: Kulkarni Mukund G. , Davawala Saryu I. , Dhondge Attrimuni P. , Gaikwad Dnyaneshwar D. , Borhade Ajit S. , Chavhan Sanjay W. 
Published: April 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Unexpected Synthesis of Substituted 9b,9c‐Dihydro‐5‐oxa‐2‐azacyclopenta[2,3]cyclopropa [1,2‐a]naphthalene‐1,3,4‐triones According to a Modified Reformatsky Reaction.
Authors: Shchepin V. V. , Silaychev P. S. , Stepanyan Yu. G. 
Published: April 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Synthesis of Novel 2‐Aminoimidazo[4,5‐b]pyridines, Including the Thieno Analogue of the Cooked‐Food Mutagen IFP.
Authors: Bjoerk Malin , Grivas Spiros 
Published: April 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Use of Stille‐Type Cross‐Coupling as a Route to Oligopyridylimines.
Authors: Champouret Yohan D. M. , Chaggar Rajinder K. , Dadhiwala Ishaq , Fawcett John , Solan Gregory A. 
Published: April 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Racemic and Diastereoselective Synthesis of Aryl and Heteroaryl Tetrahydroisoquinolines via the Pictet—Spengler Reaction.
Authors: Aubry Sylvain , Pellet‐Rostaing Stephane , Faure Rene , Lemaire Marc 
Published: April 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Synthesis of 4‐Aryl‐5‐oxo‐1H,4H‐5,6,7,8‐tetrahydroquinoline and 4‐Aryl‐5‐oxo‐1H‐4,5,6,7‐tetrahydrocyclopenteno[b]pyridine Derivatives by Ultrasound Irradiation and by Conventional Methods.
Authors: Thirumalai D. , Murugan P. , Ramakrishnan V. T. 
Published: April 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
3,4‐Vinylenedioxythiophene (VDOT): A New Building Block for Thiophene‐Based π‐Conjugated Systems.
Authors: Leriche Philippe , Blanchard Philippe , Frere Pierre , Levillain Eric , Mabon Gilles , Roncali Jean 
Published: April 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
First Example of Synthesis of Thieno[2,3‐d]pyrimidine‐6‐carbaldehydes by Oxidation of Thieno[2,3‐d]pyrimidin‐6‐yl Methanols with Molecular Iodine.
Authors: Tumkevicius S. , Navickas V. , Dailide M. 
Published: April 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
One‐Pot Synthesis of N‐Chloroacetyl 1‐Aminoalkyl Phosphonates — Precursors of 4‐Phosphono‐β‐lactams.
Authors: Moonen Kristof , Stevens Christian V. 
Published: April 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Preparation of 5‐Acyl‐2‐amino‐1,3‐selenazoles by the Reaction of Selenazadienes with α‐Haloketone.
Authors: Koketsu Mamoru , Kogami Masakazu , Ando Hiromune , Ishihara Hideharu 
Published: April 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
A New Practical Synthesis of Germylalkoxydienes, Acylgermanes and Ethynylgermanes from α,β‐Unsaturated and α‐Phenyl Acetals.
Authors: Allasia Sara , Deagostino Annamaria , Prandi Cristina , Zavattaro Chiara , Venturello Paolo 
Published: April 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Poly‐N‐methylated α‐Peptides: Synthesis and X‐Ray Structure Determination of β‐Strand Forming Foldamers
Authors: Zhang Suode , Prabpai Samran , Kongsaeree Palangpon , Arvidsson Per I. 
Published: April 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
A Novel Nicotinic Acetylcholine Receptor Antagonist Radioligand for PET Studies.
Authors: Ding Yu‐Shin , Kil Kun‐eek , Lin Kuo‐Shyan , Ma Wei , Yokota Yasuno , Carroll Ivy F. 
Published: April 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Synthetic Study for Two 2H‐Chromenic Acids, 8‐Chlorocannabiorcichromenic Acid and Mycochromenic Acid.
Authors: Yamaguchi Seiji , Nedachi Masahiro , Maekawa Mikiko , Murayama Yohei , Miyazawa Masahiro , Hirai Yoshiro 
Published: April 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Aplysamine‐1 and Related Analogues as Histamine H3 Receptor Antagonists.
Authors: Swanson Devin M. , Wilson Sandy J. , Boggs Jamin D. , Xiao Wei , Apodaca Richard , Barbier Ann J. , Lovenberg Timothy W. , Carruthers Nicholas I. 
Published: April 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Isolation, Structure Elucidation, Antioxidative and Immunomodulatory Properties of Two Novel Dihydrocoumarins from Aloe vera.
Authors: Zhang Xiu‐feng , Wang Hong‐mei , Song Yuan‐li , Nie Li‐hua , Wang Lan‐fen , Liu Bin , Shen Ping‐ping , Liu Yang 
Published: April 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
The Discovery of a Potent and Selective Lethal Factor Inhibitor for Adjunct Therapy of Anthrax Infection.
Authors: Xiong Yusheng , et al. et al. 
Published: April 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Inhibition of DNA Helicases with DNA‐Competitive Inhibitors.
Authors: Dubaele Sandy , Jahnke Wolfgang , Schoepfer Joseph , Fuchs Jean , Chene Patrick 
Published: April 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Enhanced FTase Activity Achieved via Piperazine Interaction with Catalytic Zinc.
Authors: Njoroge F. George , Vibulbhan Bancha , Pinto Patrick , Strickland Corey , Bishop W. Robert , Nomeir Amin , Girijavallabhan Vivyoor 
Published: April 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Design, Synthesis, and Evaluation of 2‐Alkoxydihydrocinnamates as PPAR Agonists.
Authors: Lu Ying , Guo Zongru , Guo Yanshen , Feng Jun , Chu Fengming 
Published: April 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Towards Reaction Selectivities of Imines and Aziridines
Authors: Hou Xue Long , Wu Jie , Fan Ren Hua , Ding Chang Hua , Luo Zhi Bin , Dai Li Xin 
Published: April 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Natural Products from Marine Organisms and Their Associated Microbes
Authors: Koenig Gabriele M. , Kehraus Stefan , Seibert Simon F. , Abdel‐Lateff Ahmed , Mueller Daniela 
Published: April 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Structural Diversity of Host—Guest and Intercalation Complexes of Fullerene C60
Authors: Makha Mohamed , Purich Ariaan , Raston Colin L. , Sobolev Alexandre N. 
Published: April 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Preparation of Polymer‐Supported Chiral 1,2‐Diamines and Their Application to Asymmetric Reaction
Authors: Itsuno Shinichi , Haraguchi Naoki , Takahashi Miyuki 
Published: April 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Calorimetric Investigation of Phase Transitions Occurring in Molecular‐Based Magnets
Authors: Sorai Michio , Nakano Motohiro , Miyazaki Yuji 
Published: April 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Prokaryotic Nucleotide Excision Repair: The UvrABC System
Authors: Truglio James J. , Croteau Deborah L. , Van Houten Bennett , Kisker Caroline 
Published: April 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
π‐Conjugated Systems: Can Phosphole Offer More than Pyrrole?
Authors: Hissler Muriel , Lescop Christophe , Reau Regis 
Published: April 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Femtosecond Dynamics on 2‐(2′‐Hydroxy‐4′‐diethylaminophenyl)benzothiazole: Solvent Polarity in the Excited‐State Proton Transfer
Authors: Cheng Yi‐Ming , Pu Shih‐Chieh , Hsu Chia‐Jung , Lai Chin‐Hung , Chou Pi‐Tai 
Published: April 2006

AbstractDetailed insights into the excited‐state enol(N*)–keto(T*) intramolecular proton transfer (ESIPT) reaction in 2‐(2′‐hydroxy‐4′‐diethylaminophenyl)benzothiazole (HABT) have been investigated via steady‐state and femtosecond fluorescence upconversion approaches. In cyclohexane, in contrast to the ultrafast rate of ESIPT for the parent 2‐(2′‐hydroxyphenyl)benzothiazole (>2.9±0.3×1013 s−1), HABT undergoes a relatively slow rate (≈5.4±0.5×1011 s−1) of ESIPT. In polar aprotic solvents competitive rate of proton transfer and rate of solvent relaxation were resolved in the early dynamics. After reaching the solvation equilibrium in the normal excited state (Neq*), ESIPT takes place with an appreciable barrier. The results also show Neq*(enol)↔Teq*(keto) equilibrium, which shifts toward Neq* as the solvent polarity increases. Temperature‐dependent relaxation dynamics further resolved a solvent‐induced barrier of 2.12 kcal mol−1 for the forward reaction in CH2Cl2. The observed spectroscopy and dynamics are rationalized by a significant difference in dipole moment between Neq* and Teq*, while the dipolar vector for the enol form in the ground state (N) is in between that of Neq* and Teq*. Upon N→N* Franck–Condon excitation, ESIPT is energetically favorable, and its rate is competitive with the solvation relaxation process. Upon reaching equilibrium configurations Neq* and Teq*, forward and/or backward ESIPT takes place with an appreciable solvent polarity induced barrier due to differences in polarization equilibrium between Neq* and Teq*.
Calculation of the cosmogenic nuclide production topographic shielding scaling factor for large areas using DEMs
Authors: Codilean Alexandru T. 
Published: April 2006

AbstractThe recent surge of applications using terrestrial cosmogenic nuclides (TCNs) to calculate catchment‐averaged erosion rates from isotopic concentrations in fluvial sediment, and the prospect of coupling TCN production functions with numerical surface process models (SPMs), necessitate a fast and accurate algorithm for the calculation of topographic shielding. Topographic shielding refers to the proportion of the incoming cosmic radiation that is shielded by the surrounding topography, the scaling factor being defined as the ratio of the unshielded (total minus shielded) to the total (or maximum) cosmic ray flux (i.e. the flux received by a horizontal, unobstructed surface). Topography contributes to the reduction of TCN production by obstructing a certain proportion of the incoming flux and by modifying the angle of incidence. Available algorithms calculate the proportion of obstructed radiation by dividing the horizon as seen by the sample (a grid cell in the case of a DEM), into arc segments (usually of equal length) for which the average obstruction heights expressed as zenith angles are calculated. The use of these methods is feasible only when dealing with a small number of isolated samples, since the identification of obstructions when dealing with an entire area is computationally very intensive. This paper describes a method that uses a relief shadow modelling technique to identify those areas of a DEM that are under shadow (i.e. shielded), and thus to account for the obstructed radiation. This method produces results that are very similar to those obtained using a direct implementation of available methods (maximum difference between results of c. 0·1). The method based on relief shadow modelling is also faster than a direct implementation of any available method and can be readily implemented in any GIS system with raster capabilities. Copyright © 2006 John Wiley & Sons, Ltd.
Evaluation of bone regeneration by DNA release from composites of oligo(poly(ethylene glycol) fumarate) and cationized gelatin microspheres in a critical‐sized calvarial defect
Authors: Kasper F. Kurtis , Young Simon , Tanahashi Kazuhiro , Barry Michael A. , Tabata Yasuhiko , Jansen John A. , Mikos Antonios G. 
Published: April 2006

AbstractThis research examines the bone formation response to release of plasmid DNA encoding human Bone Morphogenetic Protein‐2 from hydrogel composites consisting of cationized gelatin microspheres (CGMS) embedded within a crosslinked oligo(poly(ethylene glycol) fumarate) (OPF) hydrogel network in a critical‐sized rat cranial defect model after 30 days. Four composite groups were investigated: (1) composites with 10 μg DNA loaded into the CGMS phase, (2) composites with 10 μg DNA loaded into the OPF phase, (3) composites with 100 μg DNA loaded into the OPF phase, and (4) composites without DNA (material control). Light microscopy revealed no enhancement in bone formation for groups releasing plasmid DNA, relative to the material control group. Limited formation of new bone was observed from the defect margins and within the defect for some samples. The hydrogels swelled appreciably and fragmentation of the implants was noted to varying degrees among samples within groups, with a presence of inflammatory cells related to the degree of fragmentation. The lack of enhancement in bone formation indicates that the release of plasmid DNA from the composites was not sufficient to elicit a bone regeneration response. © 2006 Wiley Periodicals, Inc. J Biomed Mater Res, 2006
ARC protects rat cardiomyocytes against oxidative stress through inhibition of caspase‐2 mediated mitochondrial pathway
Authors: Zhang Yi‐Qiang , Herman Brian 
Published: April 2006

AbstractApoptosis repressor with a CARD domain (ARC) has been demonstrated to protect heart cells against ischemia/reperfusion (I/R) injury. In this study, we investigated the mechanism by which ARC protects heart cells against oxidative stress. We monitored the extent of apoptosis and activity of multiple components of the intrinsic apoptotic pathway in rat cardiac myoblast cell line H9c2 with either reduced or increased expression of ARC during oxidative stress. Overexpression of ARC‐inhibited oxidative stress‐induced caspase‐2/3 activation, cytochrome c release, and translocation of Bax to mitochondria. Furthermore, phosphorylation of ARC at threonine 149 was found to be critical to its function. ARC containing a T149A mutation failed to translocate to mitochondria, did not inhibit caspase‐2 activation, and had a dominant negative effect against the protective effect of endogenous ARC during oxidative stress. In addition, wild‐type ARC but not the T149A mutant inhibited cell death induced by overexpression of caspase‐2. Using a yeast two‐hybrid (YTH) screening approach and co‐immunoprecipitation (Co‐IP), we found that protein phosphatase 2C (PP2C) interacted with ARC and that PP2C mediated‐dephosphorylation of ARC inhibited its anti‐apoptotic activity. Eliminating either the N‐terminal CARD domain or the C‐terminal P/E domain also abolished the anti‐apoptotic function of ARC, suggesting that full‐length ARC is required for its apoptotic inhibition. These results indicate that ARC plays an important role in protection of H9c2 cells against oxidative stress‐induced apoptosis by phosphorylation‐dependent suppression of the mitochondria‐mediated intrinsic pathway, partially initiated through the activation of caspase‐2. J. Cell. Biochem. 99: 575–588, 2006. © 2006 Wiley‐Liss, Inc.
Cyclooxygenase‐2 as a signaling molecule in radiation‐induced bystander effect
Authors: Hei Tom K. 
Published: April 2006

AbstractRadiation‐induced bystander effect represents a paradigm shift in our understanding of the radiobiological effects of ionizing radiation in that extranuclear and extracellular effects may also contribute to the final biological consequences of exposure to low doses of radiation. Evidence suggests that targeted cytoplasmic irradiation results in mutation in the nucleus of the “hit” cells and that cells, which are not directly hit by an alpha particle, whether nuclear or cytoplasm, but are in the vicinity of one that does get hit, contribute to the genotoxic response of the cell population. Although radiation‐induced bystander effects have been well documented in a variety of biological systems, the mechanism is not known. Using the Columbia University charged particle beam in conjunction with a novel strip dish design, we showed recently that the cyclooxygenase‐2 (COX‐2) signaling cascade plays an essential role in the bystander process. Treatment of bystander cells with NS‐398, which suppresses COX‐2 activity, significantly reduced the bystander effect as well as the induction of the mitogen‐activated protein kinase (MAPK) pathways. These results provided the first evidence that the COX‐2‐related pathway, which is essential in mediating cellular inflammatory responses, is the critical signaling link for the bystander phenomenon. A better understanding of the cellular and molecular mechanisms of the bystander phenomenon together with evidence of their occurrence in vivo will allow us to formulate a more accurate model in assessing the health effects of low doses of ionizing radiation. © 2006 Wiley‐Liss, Inc.
Simultaneous control of the stereospecificity and molecular weight in the ruthenium‐catalyzed living radical polymerization of methyl and 2‐hydroxyethyl methacrylates and sequential synthesis of stereoblock polymers
Authors: Shibata Takuya , Satoh Kotaro , Kamigaito Masami , Okamoto Yoshio 
Published: April 2006

AbstractThe stereospecific living radical polymerizations of methyl methacrylate (MMA) and 2‐hydroxyethyl methacrylate (HEMA) were achieved with a combination of ruthenium‐catalyzed living radical and solvent‐mediated stereospecific radical polymerizations. Among a series of ruthenium complexes [RuCl2(PPh3)3, Ru(Ind)Cl(PPh3)2, and RuCp*Cl(PPh3)2], Cp*–ruthenium afforded poly(methyl methacrylate) with highly controlled molecular weights [weight‐average molecular weight/number‐average molecular weight (Mw/Mn) = 1.08] and high syndiotacticity (r = 88%) in a fluoroalcohol such as (CF3)2C(Ph)OH at 0 °C. On the other hand, a hydroxy‐functionalized monomer, HEMA, was polymerized with RuCp*Cl(PPh3)2 in N,N‐dimethylformamide and N,N‐dimethylacetamide (DMA) to give syndiotactic polymers (r = 87–88%) with controlled molecular weights (Mw/Mn = 1.12–1.16). This was the first example of the syndiospecific living radical polymerization of HEMA. A fluoroalcohol [(CF3)2C(Ph)OH], which induced the syndiospecific radical polymerization of MMA, reduced the syndiospecificity in the HEMA polymerization to result in more or less atactic polymers (mm/mr/rr = 7.2/40.9/51.9%) with controlled molecular weights in the presence of RuCp*Cl(PPh3)2 at 80 °C. A successive living radical polymerization of HEMA in two solvents, first DMA followed by (CF3)2C(Ph)OH, resulted in stereoblock poly(2‐hydroxyethyl methacrylate) with syndiotactic–atactic segments. © 2006 Wiley Periodicals, Inc. J Polym Sci Part A: Polym Chem 44: 3609–3615, 2006