bluuebunny/crossref_metadata_2025_split huggingface dataset:
Maternal serum free ß‐hCG and PAPP‐A in patients with habitual abortion‐influence on first‐trimester screening for chromosomal abnormalities
Authors: Heinig J. , Steinhard J. , Schmitz R. , Nofer J.‐R. , Kiesel L. , Klockenbusch W. 
Published: June 2007

AbstractObjectiveTo explore if maternal serum free ß‐hCG and pregnancy‐associated plasma protein A (PAPP‐A) levels in the first‐trimester of pregnancy are altered in patients with habitual abortions and if there is an effect on first‐trimester screening for Down syndrome.MethodsA retrospective study was conducted on 913 normal singleton fetuses that underwent first‐trimester combined screening for Down syndrome. Maternal serum PAPP‐A and free β‐hCG were compared between patients with (n = 64) and without habitual abortions (n = 849).ResultsThe medians ± SD log10 MoM of PAPP‐A and free β‐hCG ± SD in patients with and without habitual abortions were 0.063 ± 0.28 versus − 0.014 ± 0.27 and − 0.001 ± 0.27 versus − 0.018 ± 0.31, with a p value of 0.042 and 0.87, respectively. The screen positive rate setting the cut off at 1:350 looking at the background risk for trisomy 21 was 71.4% in women with and 81.2% in women without habitual abortion, after combined first‐trimester screening it was 7.8% in women with and 10.1% in women without recurrent abortion.ConclusionsPatients with habitual abortions have slightly increased maternal serum PAPP‐A levels in the first‐trimester. This marginal difference seems not to effect risk calculation in combined first‐trimester screening for trisomy 21. Copyright © 2007 John Wiley & Sons, Ltd.
Parental mosaic trisomy 21 detected following maternal cell contamination of an amniotic fluid specimen from a normal male pregnancy
Authors: Street Melissa L. , Barber John C. K. , Boyle Tracy A. , Ellis Katrina H. , Bullman Hilary , Homfray Tessa 
Published: June 2007

AbstractWe report a case of maternal mosaic trisomy 21 ascertained at prenatal diagnosis as a result of maternal cell contamination of an amniotic fluid sample. A 34 year old female was referred for karyotyping because of a previous trisomy 21 pregnancy. Chromosome analysis of primary in situ cultures showed a karyotype of 47,XX, + 21[6]/46,XY[32]/46,XX[2]. Molecular testing demonstrated maternal cell contamination of the amniotic fluid sample and G‐banded karyotyping of maternal blood showed that 3/200 cells had trisomy 21, consistent with the mother being a Down syndrome mosaic. A normal male baby with a 46,XY chromosome complement was delivered at 30 weeks. This case emphasises the need for close collaboration between cytogenetic and molecular genetics laboratories in resolving unusual cases of mosaicism. Copyright © 2007 John Wiley & Sons, Ltd.
Managing the consultant and the client: A two‐handled crosscut saw
Authors: Turner Dorothy Earnest , Connors Maureen R. 
Published: June 2007

AbstractThis article focuses on managing the client and the concultant with a performance appraisal process. The authors use their current practical experiences to consider the management of an effective client‐consultant relationship. Dorothy writes from her perspective as a training director and user consultants and Maureen from her experience as an independent consultant providing management training and consulting services in the Metropolitan Washington area.
Audit of ophthalmological examination in psychiatry
Authors: Kannabiran Muthukumar , Singh Yolisha , Narayan Gopinath 
Published: June 2007

AbstractPsychiatrists revealed in a survey that they feel that ophthalmological examination is important for patient care.Further audit of their practice showed that training improved the percentage of patients given such examinations.The authors discuss the implications of these findings for the training of psychiatrists. Copyright © 2007 Wiley Interface Ltd
Primary Care Mental Health & Education
Authors: White Corinna , Smith Steve , Wheen Lucy , Maguire Claire , Mullarkey Kevin 
Published: June 2007

AbstractImproving the management of depression in primary careWith the overarching aim of making the management of depression easier, Lewisham PCT have implemented a multifaceted programme to develop primary health care workers' skills, knowledge and resources so as to improve their service to patients with depression. Now in its second year, the programme has, and still is, constantly evolving. This article outlines the programme's key messages and components during its first year, and briefly refers to its expansion and future aims.Primary care mental health services for 16‐19 year oldsStudies suggest that many young people who would benefit from accessing mental health services do not do so, as they fall into the gap between child and adult services. This report outlines the results of a project carried out within Bury Mental Health Services to establish what young people want from primary care mental health services and whether current service provision meets their needs. Copyright © 2007 Wiley Interface Ltd
Degradation of permafrost in the Xing'anling Mountains, northeastern China
Authors: Jin Huijun , Yu Qihao , Lü Lanzhi , Guo Dongxin , He Ruixia , Yu Shaopeng , Sun Guangyou , Li Yingwu 
Published: June 2007

AbstractPermafrost in the Da and Xiao Xing'anling Mountains in northeastern China is warm, thin and sensitive to climatic warming. In the 1970s, the southern limit of permafrost (SLP) was empirically correlated to the −1 to 0°C isotherms of mean annual air temperature (MAAT) in the western part of the Da Xing'anling Mountains, to about 0°C in the northern part of the Songnen Plain, and to 0 to +1°C in the eastern part of the Xiao Xing'anling Mountains. Climate warming and deforestation have led to permafrost degradation as shown by deepening of the active layer, thinning permafrost, rising ground temperatures, expanding taliks and the disappearance of permafrost patches. The present position of the SLP was estimated using the −1.0 to +1.0°C MAAT isotherms for 1991–2000. Compared to the SLP in the 1970s, areas of sporadic discontinuous and isolated patchy permafrost have decreased by 90,000–100,000 km2, or 35–37% of their total areal extent (260,000–270,000 km2) in the 1970s. Recent field observations along the Hei'he to Bei'an Highway, the proposed Mo'he to Daqing Crude Oil Pipeline route and the Hai'lar to Daqing Highway confirm these changes. Continuing northward shifting of the SLP is likely to occur during the next 40–50 years under a warming of 1.0–1.5 °C, reducing the permafrost areal extent to an estimated 35% of that in the 1970s and 1980s. Copyright © 2007 John Wiley & Sons, Ltd.
The Nobel trail of Vincent du Vigneaud
Authors: Ragnarsson ULF 
Published: June 2007

AbstractThe Nobel Prize for chemistry of 1955 was awarded to Vincent du Vigneaud. After a brief outline of his career and accomplishments, some archive material related to this decision of the Royal Swedish Academy of Sciences is presented. Other archive studies have shown that du Vigneaud was also considered for the corresponding prize in physiology or medicine. Copyright © 2007 European Peptide Society and John Wiley & Sons, Ltd.
Multimer formation by FKBP‐12: roles for cysteine 23 and phenylalanine 36
Authors: Schories Barbara , Nelson Thomas E. , Sane David C. 
Published: June 2007

AbstractFKBP‐12 mediates the immunosuppressive actions of FK506 and rapamycin, and modulates the activities of the ryanodine, IP3 and type 1 TGF‐ß receptors. Additionally, FKBP‐12 possesses cis‐trans peptidylprolyl isomerase (rotamase) activity. We have discovered that recombinant FKBP‐12 readily forms a dimer and a small amount of trimer under nonreducing conditions. A mutant with substitution at the sole cysteine residue of FKBP‐12 (C23S) did not form dimers or trimers. Using mutants with 5% or less rotamase activity, the formation of dimers was independent of enzymatic activity. The formation of trimers was abrogated by a F36Y substitution, even though dimer formation was preserved. Dimers were also observed with native FKBP‐12 that was detached from rabbit skeletal muscle ryanodine receptors using FK590. The multimers of FKBP‐12 could interact with molecular targets distinctly from the FKBP‐12 monomer, for example, by facilitating the assembly of multimeric receptors or coordinating the activity of receptor subunits. Copyright © 2007 European Peptide Society and John Wiley & Sons, Ltd.
Robotic telesurgery: a real‐world comparison of ground‐ and satellite‐based internet performance
Authors: Rayman R. , Croome K. , Galbraith N. , McClure R. , Morady R. , Peterson S. , Smith S. , Subotic V. , Van Wynsberghe A. , Patel R. , Primak S. 
Published: June 2007

AbstractBackgroundTelesurgery was performed with ground vs. satellite networks, and differing satellite bandwidths.MethodsThe networks were compared during internal mammary artery (LIMA) dissection in pigs (n= 8). Length of LIMA dissected and surgical quality (five‐point scale) were recorded. Also, satellite bandwidth was decreased (n= 7) to determine a limit for telesurgery.ResultsNo significant differences existed in LIMA dissection during the ground (4.3 ± 0.5 cm) and satellite phases (5.4 ± 1.1 cm;p> 0.05) or in quality of surgery, although latency on satellite was 10 times greater (55 vs. 600 ms). With decreasing satellite bandwidth, surgery was not possible below 3 Mb/s, and quality of surgery was significantly decreased comparing 9 Mb/s (4.38 ± 0.66/5) to 3Mb/s (4.10 ± 0.80/5;p< 0.05).ConclusionsSatellite communication is a viable telesurgical modality. Satellite bandwidth should be above 5 Mb/s during telesurgery if used primarily or as back‐up. Copyright © 2007 John Wiley & Sons, Ltd.
An almost‐bijective proof of an asymptotic property of partitions
Authors: Jaggard Aaron D. 
Published: June 2007

AbstractLet 𝒫n be the set of all distinct ordered pairs (λ,λi), where λ is a partition of n and λi is a part size of λ. The primary result of this note is a combinatorial proof that the probability that, for a pair (λ,λi) chosen uniformly at random from 𝒫n, the multiplicity of λi in λ is 1 tends to 1/2 as n →∞. This is inspired by work of Corteel, Pittel, Savage, and Wilf (Random Structures and Algorithms 14 (1999), 185–197). © 2007 Wiley Periodicals, Inc. Random Struct. Alg., 2007
Perturbation Solutions for the Particle Trajectories of a Gas‐Solid Mixture Entering a Curved Duct
Authors: Yeung Woon‐Shing 
Published: June 2007

AbstractA matched asymptotic expansion solution was found for the particle trajectories in a curved duct when the non‐dimensional momentum equilibration length L̃m is small. The motion of the carrier fluid was assumed to be uniform. The approximate solution was compared with the exact numerical solution and good agreements were found.
On a System of Diffusion‐Reaction Equations
Authors: Gajewski H. , Zacharias K. 
Published: June 2007

AbstractA system of diffusion‐reaction equations modelling polymerization is considered. Especially the large time behaviour is studied. It can be shown that the system has a well‐defined asymptotic state which can be described by explicit formulae. These formulae allow the identification of the essential parameters — diffusion coefficient and reaction constant — from appropriate experimental data.
Torsion of a Transversely Isotropic Cylinder in the Theory of Creep
Authors: Gupta S. K. , Rana V. D. 
Published: June 2007

AbstractTransitional stresses for a transversely isotropic circular cylinder subjected to torsion have been derived. It has been shown that the asymptotic solution through the stress and stress‐difference gives the plastic and creep stresses respectively. The effect of transverse isotropy is presented graphically. The results indicate that the value of maximum shear stress for a cylinder of transversely isotropic material is greater than that of an isotropic incompressible material and it increases with the increase in measure ‘n’. For an isotropic incompressible material, as a particular case, the results are the same as given by Marin.
The Weak Interaction Induced Pressure due to the Stepwise‐Deceleration of a Flat Plate in Hypersonic Flow
Authors: Rodkiewicz Cz M. , Gupta R. N. 
Published: June 2007

AbstractA semi‐infinite plate is exposed to the stepwise‐decelerated hypersonic flow at zero angle of attack. The boundary layer reconfiguration gives rise to an induced pressure. To obtain this temporal pressure distribution, the transformed momentum and energy equations have been solved using the approach of Ref. [1]. These solutions are used to evaluate the displacement thickness for the unsteady boundary layer. The differentiated displacement thickness is finally used in the induced pressure expression involving the acoustic approximation. The shearing stress and heat transfer at the wall are obtained.
A Comparative Analysis of Some Semi‐Linear Parabolic Systems Modelling the Dynamics of Fast Nuclear Reactors
Authors: De Mottoni P. , Tesei A. 
Published: June 2007

AbstractStarting from a class of parabolic systems considered in the literature for describing the operation of fast nuclear reactors, two kinds of modified systems are investigated: one accounts for retarded neutrons, the other one involves a small neutron feedback. It is shown that these systems, while equivalent to the original ones for any finite value of the neutron velocity, behave in a substantially different way in the limiting case of diverging neutron velocity. In particular, considering reta ded neutrons or neutron feedback terms avoids the appearance of undamped oscillations, which characterizes the behavior of the original systems in the same limiting case.
Zur projektiven Invarianz von Wackelstrukturen
Authors: Wunderlich W. 
Published: June 2007

AbstractDie Tatsache, daß die infinitesimale Beweglichkeit von Ausnahmestabwerken oder ‐polyedern gegenüber projektiven Transformationen invariant ist, wird auf einem natürlichen Weg bewiesen, der geeignete Geschwindigkeitsdiagramme benützt. Geschwindigkeitstransformationen, die mit der auf eine Wackelstruktur ausgeübten Affinität oder Kollineation verträglich sind, werden explizit angegeben.
Analytische Berechnung nichtlinearer Eigenschwingungen durch kanonische Transformation
Authors: Schräpel H.‐D. 
Published: June 2007

AbstractIn dieser Arbeit wird eine neue analytische Methode zur angenäherten Berechnung nichtlinearer Eigenschwingungen entwickelt. Zunächst werden die Bewegungsgleichungen durch die bekannte lineare Transformation in den linearen Termen entkoppelt. Die gesuchte kanonische Transformation kann dann bei nicht zu großen nichtlinearen Koppeltermen leicht angenähert berechnet werden. Es genügt die Integration der Koppelenergie nach der Zeit, wobei Für die Lage‐ und Impulskoordinaten gerade die Lösungen des entkoppelten Systems einzusetzen sind. Durch Differenzieren folgen dann die gesuchten Näherungslösungen des gekoppelten Systems. Eine nichtlineare Schwingerkette und das elastische Pendel werden mit dieser Methode untersucht.
Thermoelastic Problem for a Griffith Crack in a Plate whose Shear Modulus is an Exponential Function of the Temperature
Authors: Hata T. 
Published: June 2007

AbstractIn this paper, we examine an analysis of thermal stresses taking into account the temperature‐dependent properties, in which the variation of the shear modulus with temperature assumed to be an exponential function. Using the perturbation method, general equations for the displacements are found. The equations can be solved by using four displacement functions. Following this method, a solution is derived for calculating the stress intensity factor for a Griffith crack in a temperature‐sensitive plate under a linear temperature distribution, where we assume that the temperature field is not disturbed by the crack. (Under these conditions, if a plate is temperature‐insensitive, the stress intensity factor for the crack is zero.) In this case, whether the stress intensity factor is zero or not depends only on the temperature variation of the coefficient of thermal expansion. A numerical example is given for a plate made of steel. Results show the effect of temperature‐dependent properties clearly.
Herleitung einer Direktortheorie für Kontinua mit lokalen Krümmungseigenschaften
Authors: Zastrau B. , Rothert H. 
Published: June 2007

AbstractIn der vorliegenden Arbeit werden die theoretischen Grundlagen für die Berechnung orientierter Werkstoffe im Rahmen einer verallgemeinerten Cosserat theorie bereitgestellt. Mit der Einführung vektorwertiger Direktoren, die auch eine lokale Änderung der Strukturkrümmung erfassen, werden unter Beachtung der Hauptsätze der Thermodynamik die Feldgleichungen für Massenerhalt, Gleichgewicht und Symmetrie des Direktorspannungstensors hergeleitet. Zur Erfassung der erweiterten kinematischen Möglichkeiten des eingeführten Direktormodells wird ein entsprechend verändertes Grundkonzept der Mechanik vorgestellt. Mit den konstitutiven Beziehungen für ein einfachst mögliches Direktorkontinuum gelingt es ohne Einschränkung der Allgemeingültigkeit, die dargelegte Theorie für die Anwendung mit Finiten Elementen aufzubereiten. Auf der Grundlage von numerischen Ergebnissen erfolgt abschließend eine Diskussion der Bedeutung der eingeführten Direktoreigenschaften.
Parameter Identification in Transverse Mixing Models of Rivers – an Inverse Problem for a Parabolic Equation
Authors: Stoyan G. , Baumert H. 
Published: June 2007

AbstractThe basic equation of transverse mixing in rivers and streams is given. A simple analytical solution (Gaussian distribution) is derived, firstly, assuming uniform transverse distributions of longitudinal flow velocity, depth, and transverse mixing coefficient. Using a modified linear regression technique, the cross sectional average of the transverse mixing coefficient is determined. Then, to get an estimate of the cross sectional distribution of the mixing coefficient, a finite difference scheme was applied in order to solve the mixing equation numerically, and the identification of the mixing coefficient was carried out by a nonlinear least squares technique, combining several minimization methods. The numerical methods described were successfully applied to experimental data of the Elbe river and led to certain crossmixing models. In applications, these models may save measurement expense and serve as scientific tools to predict the influence of large waste water treatment plants on water quality in the longitudinal and transversal coordinate of the river.
Verzögerung und virtuelle Masse bei Umströmung eines Hindernisses
Authors: Kühnau R. 
Published: June 2007

AbstractBringt man einen Körper in eine ebene Parallelströmung einer inkompressiblen reibungsfreien Flüssigkeit, wird die Strömung gestört, und die Zeit ändert sich, die ein Teilchen auf dem Wege zwischen zwei senkrecht zur ursprünglichen Strömungsrichtung liegenden Geraden benötigt. Es wird hier gezeigt, daß sich diese Zeit in einem gewissen Sinne vergrößert, wobei ein einfacher Zusammenhang mit der virtuellen Masse besteht.
Objective Strain Acceleration Measures in Nonlinear Analysis of Structures
Authors: Stolarski H. 
Published: June 2007

AbstractA method of derivation of the accelerations of generalized strains for various structures is presented. Contrary to the common approach to the problem, consisting in successive differentiation of the components of appropriate strain tensor, the method utilizes the general formulas, defining objective time derivatives of tensors. In the structural analysis, such a way of derivation of the higher rates of the strain tensor is less involved and permits the rates associated with various objective time derivatives to be systematically obtained.
Nasal septal perforation and antiphospholipid syndrome (Hughes syndrome)
Authors: Banerjee S S , Lammin K , Carpentier J de 
Published: June 2007

AbstractWe present the case of a 19-year-old woman who developed a nasal septal perforation and atrophic rhinitis following septal surgery. During the subsequent five years, she also experienced intermittent episodes of swelling and ischaemia of the left foot, as well as livedo reticularis. Ultimately, haematological investigations revealed the presence of lupus anticoagulant and elevated antiphospholipid immunoglobulin M levels. A diagnosis of antiphospholipid syndrome (Hughes syndrome) was made.A search of the literature revealed that nasal septal perforation has been described in up to 0.8 per cent of patients with antiphospholipid syndrome. However, it is undescribed in the otorhinolaryngological literature. The impact of this syndrome on otorhinolaryngology practice is examined.
Bacterial biofilm adherence to middle-ear ventilation tubes: scanning electron micrograph images and literature review
Authors: Barakate M , Beckenham E , Curotta J , Cruz M da 
Published: June 2007

Introduction: The organisms that cause many device-related and other chronic infections actually grow in biofilms in or on these devices. We sought to examine the role of biofilm formation in chronic middle-ear ventilation tube infection.Case report: Scanning electron micrograph images are presented which demonstrate biofilm on a middle-ear ventilation tube removed from a five-year-old child's chronically discharging ear. A review of the relevant international literature explores the role of biofilms in chronic infection and discusses potential intervention strategies.Conclusion: Biofilms may be responsible for chronic middle-ear ventilation tube infection that resists treatment with conventional antibiotics.
Suture techniques in nasal tip sculpture: current concepts
Authors: Lo S , Rowe-Jones J 
Published: June 2007

AbstractObjectives:The three-dimensional anatomy and conspicuous location of the nasal tip makes it one of the most challenging sites of facial plastic surgery. This article reviews literature on nasal tip sculpture using suture techniques, as well as the authors' own experience.Methods:A search was conducted using Pubmed, the Google internet search engine and the authors' files, using the keywords ‘nasal tip’, ‘suture’, ‘rhinoplasty’ and ‘septorhinoplasty’.Results:Common nasal tip suture techniques and suture algorithms are presented, along with a summary of the indications and side effects of each technique.Conclusions:Predictable long-term results are more likely to occur with minimal local tissue excision. Suture techniques remodel the shape of the nasal tip by altering the configuration of, and the relationship between, the tip cartilages and their supporting structures; they also preserve nasal tip anatomy and limit resection. Intra-operatively, the effects are immediately visible, and can be adjusted or reversed. Tip sutures should therefore be considered instead of tissue excision whenever possible.