bluuebunny/crossref_metadata_2025_split huggingface dataset:
Present State and Recent Developments of Artificial Intelligence and Machine Learning in Gastric Cancer Diagnosis and Prognosis: A Systematic Review
Authors: Patel Rushin , Patel Mrunal , Patel Zalak , Kavani Himanshu , Onyechi Afoma , Ohemeng-Dapaah Jessica , Gadhiya Dhruvkumar , Patel Darshil , Yang Chieh 
Published: March 2024

Objective: The objective of this study is to thoroughly investigate the use of artificial intelligence (AI) and machine learning (ML) techniques for diagnosing and predicting prognosis in gastric cancer, utilizing the latest available data.
Methods: Following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA)guidelines, a systematic review investigated AI and ML applications in gastric cancer diagnosis and prognostic prediction. PubMed and Google Scholar were searched from February 2019 to January 2024 using specific syntax. Eligible trials were selected based on inclusion criteria including recent publication, focus on AI and ML in gastric cancer, and reporting diagnostic or prognostic outcomes. Data were extracted and quality assessed independently, with discrepancies resolved through discussion. Due to design heterogeneity, detailed analysis was omitted, and descriptive summaries of included articles were provided.
Results: This review included a total of 8 articles. AI and ML techniques, including convolutional neural networks (CNN) and deep learning models, have played pivotal roles in accurately diagnosing chronic atrophic gastritis, predicting postoperative gastric cancer prognosis, and identifying peritoneal metastasis in gastric cancer patients. These technologies offer potential advantages such as streamlining diagnostic procedures, guiding treatment decisions, and enhancing patient outcomes in gastric cancer management.
Conclusion: In the near future, AI applications may have a significant role in the diagnosis and prognosis prediction of gastric cancer.
Requirements and Main Indicators for the Quality of Electrical Energy
Authors: Mehdiyeva A. M.  
Published: March 2024

From the calculated results, it can be seen that the to different levels in different facilities differs to a certain extent. In this case, these differences are smaller for the 10-second period and larger for the 60-second period. In addition, the shape of the histogram and the character of the parameters of the deviation are the same for all facilities. In the case of a time period of 10 seconds, the value of the mathematical deviation differs from each other by ±0.5%, and in the period of 60 seconds, ±0.7%. However, the differences of the standard deviations do not exceed ±0.1%. Thus, when using the information obtained by the statistical analyzer of the quality of deviation, it is necessary to draw all the characteristics obtained by means of this facility: the shape of the histogram, the probability of falling into different levels, the average value and the standard deviation. As a lawyer, the most stable information about the road network is standard. Taking this into account, this quantity should be used when determining the quality of the change.
The following main results were obtained: The quality indicators of electric energy are determined by the distribution of voltage, waves, the symmetrical characteristic of the three-phase periodicity and the non-sinusoidal characteristic of the voltage. The proposed control system allows real-time monitoring of energy quality.
Effect of Chemical Weed Management Practices on Weed Dynamics, Soil Microorganism and Nutrient Uptake in Blackgram [Vigna mungo (L.)]
Authors: Anusha S. , Patil D. H. , Rathod P. S. , Basavaraj K. , Dodamani B. M. 
Published: March 2024

An investigation was carried out at Zonal Agricultural Research Station, Kalaburagi, India, University of Agricultural Sciences, Raichur, Karnataka, India during kharif 2021-22 to study the effect of pre and post emergent application of weedicides on seed yield, weed dynamics, microbial population and nutrient uptake by weeds in blackgram. The results revealed that, significantly lower weed density (grassy weeds, sedges and broad leaf weeds (0.71) and weed dry weight (0.71) was observed with hand weeding at 25-30 DAS and intercultivation at 45 DAS (control) followed by sodium acifluorfen 16.5% + clodinafop propargyl 8% EC @ 1.0 kg a.i. ha-1 at 20-25 DAS [grassy weeds (1.08, 1.26 and 1.83) sedges (1.03, 1.57 and 1.47) and broad leaf weeds (1.72, 2.06 and 2.11 at 25, 50 DAS and at harvest respectively]. Weed control efficiency was significantly higher with sodium acifluorfen 16.5% + clodinafop propargyl 8% EC @ 1.0 kg a.i. ha-1 at 20-25 DAS (89.52, 90.31 and 91.17 at 25, 50 DAS and at harvest respectively) that was on par with hand weeding. Hand weeding at 25-30 DAS and intercultivation at 45 DAS recorded significantly higher population of bacteria, fungi and actinomycetes (13.82, 12.49 and 5.25 cfu x 106 g-1 soil respectively). All chemical weedicides applied either pre-emergent or post-emergent significantly reduced population of total bacteria, fungi, actinomycetes. Significantly higher nutrient uptake by weeds was recorded with weedy check (71.03, 32.00 and 56.67 kg ha-1 nitrogen, phosphorus and potassium respectively). Where as, higher nutrient uptake by blackgram was with hand weeding at 25-30 DAS and intercultivation at 45 DAS (126.25, 28.20 and 109.30 kg ha-1 nitrogen, phosphorus and potassium respectively). After the harvest, soil available nutrients status was higher with hand weeding at 25-30 DAS and intercultivation at 45 DAS (141.38, 42.10 and 298.53 kg ha-1 nitrogen, phosphorus and potassium respectively) and significantly lower nutrients were observed with weedy check (122.93, 30.17 and 220.10 kg ha-1 nitrogen, phosphorus and potassium respectively).
Study of the Operating Cost of the Electric Pump for Mine Dewatering: Case of the SOMAÏR Uranium Mine
Authors: Mahamadou Ousman , Abdoulkader Haladou Atto , Seibou Boureima , Abdourazakou Maman Hassan , Harouna Souley , Souleymane Illou Issoufa , Marou Idrissa Hamadou 
Published: March 2024

This study focuses on the operating cost of the electric pump used to extract water from the Artois mine owned by Société des Mines de l'AÏR. Exploitation of the SOMAÏR Artois mine uranium deposit is to be increased from the 20 m level to the 80, 100 or 120 m level; in the current phase of certain pits, access to the uranium deposit can only be achieved by a means that can draw off the water encountered. It is therefore essential to set up a drainage system to manage and evacuate the various water inflows. The main source of incoming water is the nearby water table, which is drained directly onto the mining unit. The current drainage system has two sumps capable of storing the various water inflows without incident. The energy balance for the three (3) years of pumping was drawn up using the electricity consumption data received. Peaks appear in August for the year 2021, followed by January 2020 and May 2022. The results show that specific energy is high, resulting in higher power consumption than water production. According to the graph of performance curves P = f(Q), the power ratings obtained for flows corresponding to the 24 m head are 25 kW at a flow rate Q = 49 l/s for pump 261; 35 kW, at a flow rate Q = 59 l/s for pump 259 and 35 kW at a flow rate Q = 105 l/s for pump 234.
Cold extends electromyography distinction between ion channel mutations causing myotonia
Authors: Fournier Emmanuel , Viala Karine , Gervais Hélène , Sternberg Damien , Arzel‐Hézode Marianne , Laforêt Pascal , Eymard Bruno , Tabti Nacira , Willer Jean‐Claude , Vial Christophe , Fontaine Bertrand 
Published: June 2006

AbstractObjectiveMyotonias are inherited disorders of the skeletal muscle excitability. Nondystrophic forms are caused by mutations in genes coding for the muscle chloride or sodium channel. Myotonia is either relieved or worsened by repeated exercise and can merge into flaccid weakness during exposure to cold, according to causal mutations. We designed an easy electromyography (EMG) protocol combining repeated short exercise and cold as provocative tests to discriminate groups of mutations.MethodsSurface‐recorded compound muscle action potential was used to monitor muscle electrical activity. The protocol was applied on 31 unaffected control subjects and on a large population of 54 patients with chloride or sodium channel mutations known to cause the different forms of myotonia.ResultsIn patients, repeated short exercise test at room temperature disclosed three distinct abnormal patterns of compound muscle action potential changes (I‐III), which matched the clinical symptoms. Combining repeated exercise with cold exposure clarified the EMG patterns in a way that enabled a clear correlation between the electrophysiological and genetic defects.InterpretationWe hypothesize that segregation of mutations into the different EMG patterns depended on the underlying pathophysiological mechanisms. Results allow us to suggest EMG guidelines for the molecular diagnosis, which can be used in clinical practice. Ann Neurol 2006
Three‐dimensional nonisothermal simulation of a coat hanger die
Authors: Wu Tingqi , Jiang Bo , Xu Shuhua , Huang Nabin 
Published: June 2006

AbstractWe studied the nonisothermal flow of Carreau fluid in a coat hanger die. A general three‐dimensional finite volume code was developed for the purpose of flow analysis. The pressure distribution and velocity distribution were obtained in addition to the temperature distribution. The results illustrated that the highest temperature occurred more by the center of manifold than by the die‐lip region. In the regions where the die gap was small relatively, the wall temperature played a key role in the determination of the temperature distribution in the melt. However, in the manifold, the viscous dissipation was the key factor that determined the temperature distribution in the melt where the heat conduction was relatively poor because of the thicker gap. © 2006 Wiley Periodicals, Inc. J Appl Polym Sci 101:2911–2918, 2006
Determination of solution viscosity characteristics of rubber seed oil based alkyds resins
Authors: Ikhuoria E. U. , Aigbodion A. I. 
Published: June 2006

AbstractThree medium oil alkyd samples of different oil length [(I) 45%, (II) 50%, and (III) 55%] were synthesized with rubber seed oil. Dilute solution viscosity measurements were carried out on the alkyd in acetone and in toluene. The parameters investigated include intrinsic viscosity [η], Huggins constant (kH), and Mark‐Houwink Sakurada constants (κ and α). The [η] values for the alkyd samples were found to be larger in acetone than in toluene. The KH values showed a regular order in acetone but not in toluene. The KH values showed no regular order in their variation with the oil content of the alkyd samples and the solvent, but the values obtained are higher in acetone than in toluene. Correlation of molecular weight (M) with [η] was also examined. [η] was observed to increase with the increase in the molecular weight of the resins. The α values obtained are in reasonable agreement with the reported ranges of α values in good solvent. The characteristics examined suggest that acetone is a better solvent for rubber seed oil alkyd resin than toluene. © 2006 Wiley Periodicals, Inc. J Appl Polym Sci 101: 3073–3075, 2006
Numerical simulation grounding system buried within horizontal multilayer earth in frequency domain
Authors: Li Zhong‐Xin , Chen Wei‐Jiang 
Published: June 2006

AbstractA novel mathematical model for accurately calculating the currents flowing along the conductors of grounding system below high voltage a.c. substations and nearby floating metallic structure buried in horizontal multilayer earth model has been developed in this paper. Not only the mutual conductive and capacitive coupling influences of leakage currents, but also mutual inductive coupling influence of network currents flowing along the conductors of grounding system and nearby floating metallic structure in the horizontal multilayer earth model have been considered in this model, and only propagation effect of electromagnetic wave within limited area of the substation has been neglected. The quasi‐static complex image method and closed form of Green's function are introduced into this model to accelerate the calculation. The model is then implemented in a computer program, which can be used to calculate currents distribution along the conductors of any configuration of grounding system, and with or without floating metallic structure under some hundreds of kHz frequency harmonic wave. Copyright © 2006 John Wiley & Sons, Ltd.
Action minimization and sharp‐interface limits for the stochastic Allen‐Cahn equation
Authors: Kohn Robert V. , Otto Felix , Reznikoff Maria G. , Vanden‐Eijnden Eric 
Published: June 2006

AbstractWe study the action minimization problem that is formally associated to phase transformation in the stochastically perturbed Allen‐Cahn equation. The sharp‐interface limit is related to (but different from) the sharp‐interface limits of the related energy functional and deterministic gradient flows. In the sharp‐interface limit of the action minimization problem, we find distinct “most likely switching pathways,” depending on the relative costs of nucleation and propagation of interfaces. This competition is captured by the limit of the action functional, which we derive formally and propose as the natural candidate for the Γ‐limit. Guided by the reduced functional, we prove upper and lower bounds for the minimal action that agree on the level of scaling. © 2006 Wiley Periodicals, Inc.
Development of off‐line and on‐line capillary electrophoresis methods for the screening and characterization of adenosine kinase inhibitors and substrates
Authors: Iqbal Jamshed , Burbiel Joachim C. , Müller Christa E. 
Published: June 2006

AbstractFast and convenient CE assays were developed for the screening of adenosine kinase (AK) inhibitors and substrates. In the first method, the enzymatic reaction was performed in a test tube and the samples were subsequently injected into the capillary by pressure and detected by their UV absorbance at 260 nm. An MEKC method using borate buffer (pH 9.5) containing 100 mM SDS (method A) was suitable for separating alternative substrates (nucleosides). For the CE determination of AMP formed as a product of the AK reaction, a phosphate buffer (pH 7.5 or 8.5) was used and a constant current (95 μA) was applied (method B). The methods employing a fused‐silica capillary and normal polarity mode provided good resolution of substrates and products of the enzymatic reaction and a short analysis time of less than 10 min. To further optimize and miniaturize the AK assays, the enzymatic reaction was performed directly in the capillary, prior to separation and quantitation of the product employing electrophoretically mediated microanalysis (EMMA, method C). After hydrodynamic injection of a plug of reaction buffer (20 mM Tris‐HCl, 0.2 mM MgCl2, pH 7.4), followed by a plug containing the enzyme, and subsequent injection of a plug of reaction buffer containing 1 mM ATP, 100 μM adenosine, and 20 μM UMP as an internal standard (I.S.), as well as various concentrations of an inhibitor, the reaction was initiated by the application of 5 kV separation voltage (negative polarity) for 0.20 min to let the plugs interpenetrate. The voltage was turned off for 5 min (zero‐potential amplification) and again turned on at a constant current of —60 μA to elute the products within 7 min. The method employing a polyacrylamide‐coated capillary of 20 cm effective length and reverse polarity mode provided good resolution of substrates and products. Dose–response curves and calculatedKivalues for standard antagonists obtained by CE were in excellent agreement with data obtained by the standard radioactive assay.
Glass–glass ceramic thermoseeds for hyperthermic treatment of bone tumors
Authors: Ruiz‐Hernández E. , Serrano M.C. , Arcos D. , Vallet‐Regí M. 
Published: June 2006

AbstractImplantable thermoseeds are synthesised from mixtures of a melt‐derived glass with composition SiO2 (40)–CaO(40)–Fe2O3(20) (mol%) and a sol–gel glass with composition SiO2(58)–P2O5(6)–CaO(36) (mol%). Structural, textural and magnetic properties of the samples are evaluated. In vitro bioactivity is assessed in order to determine the potential capability to bond to living bone. In spite of the low textural properties of the material, a bioactive behavior is observed as a result of the sol–gel glass content. Although the crystallization of the glass ceramic provides the magnetic phase, the presence of sol–gel glass modifies the magnetic properties, improving the heating power. For the first time, hyperthermia heating experiments as well as preliminary biocompatibility assays have been carried out for this kind of material. The ability to reach hyperthermic temperature range together with the bioactive behavior makes this biomaterial a very promising candidate for bone cancer treatment. © 2006 Wiley Periodicals, Inc. J Biomed Mater Res, 2006
Monoclonal antibody Rip specifically recognizes 2′,3′‐cyclic nucleotide 3′‐phosphodiesterase in oligodendrocytes
Authors: Watanabe Masatomo , Sakurai Yoko , Ichinose Tatsuya , Aikawa Yoshikatsu , Kotani Masaharu , Itoh Kouichi 
Published: June 2006

AbstractThe antigen recognized with monoclonal antibody (mAb) Rip (Rip‐antigen) has been long used as a marker of oligodendrocytes and myelin sheaths. However, the identity of Rip‐antigen has yet to be elucidated. We herein identified the Rip‐antigen. No signal recognized by mAb‐Rip was detected by immunoblot analyses in the rat brain, cultured rat oligodendrocytes, or the oligodendrocyte cell line CG‐4. As this antibody worked very well on immunocytochemistry and immunohistochemistry, Rip‐antigen was immunopurified with mAb‐Rip from the differentiated CG‐4 cells. Eight strong‐intensity bands thus appeared on 5–20% SDS‐PAGE with SYPRO ruby fluorescence staining. To identify these molecules, each band extracted from the gel was analyzed by MALDI‐QIT/TOF mass spectrometry. We found an interesting molecule in the oligodendrocytes from an approximately 44‐kDa band as 2′,3′‐cyclic nucleotide 3′‐phosphodiesterase (CNP). To test whether CNP was recognized by mAb‐Rip, double‐immunofluorescence staining was performed by using Alexa Fluor 488‐conjugated mAb‐Rip and Alexa Fluor 568‐conjugated mAb‐CNP in the rat cerebellum, mouse cerebellum, cultured rat oligodendrocytes, and CG‐4 cells. The Rip‐antigen was colocalized with CNP in these cells and tissues. To provide direct evidence that CNP was recognized by mAb‐Rip, rat Cnp1‐transfected HEK293T cells were used for double‐immunofluorescence staining with mAb‐Rip and mAb‐CNP. The Rip‐antigen was colocalized with CNP in rat Cnp1‐transfected HEK293T cells, but the antigen was not detected by mAb‐Rip and mAb‐CNP in mock‐transfected HEK293T cells. Overall, we have demonstrated that the antigen labeled with mAb‐Rip is CNP in the oligodendrocytes. © 2006 Wiley‐Liss, Inc.
Novel explant model to study mechanotransduction and cell–cell communication
Authors: Hoffler C. Edward , Hankenson Kurt D. , Miller Joshua D. , Bilkhu Sukhinderdeep K. , Goldstein Steven A. 
Published: June 2006

AbstractTo understand in situ behavior of osteocytes, we characterized a model of osteocytes in their native bone matrix and demonstrated real‐time biologic activity of osteocytes while bending the bone matrix. Using 43 male Sprague‐Dawley rats, dumbbell‐shaped explants were harvested from stainless steel femoral implants after 6–12 weeks and incubated in culture medium or fixed. Sixteen specimens were used to determine bone volume density (BV/TV), volumetric bone mineral density (BMD) and histology for different implantation periods. Osteocyte viability was evaluated by L‐lactate dehydrogenase (LDH) activity in 12 cultured explants. Confocal microscopy was used to assess tracer diffusion in three explants and changes in osteocyte pH of a mechanically loaded explant. From 6 to 12 weeks, explant BV/TV and volumetric BMD trended up 92.5% and 101%, respectively. They were significantly and highly correlated. Tissues were uniformly intramembranous and all bone cell types were present. Explants maintained LDH activity through culture day 8. Diffusion at 200 µM was limited to 1,209 Da. Explants appeared capable of reproducing complex bone biology. This model may be useful in understanding osteocyte mechanotransduction in the context of a physiologically relevant bone matrix. © 2006 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 24:1687–1698, 2006
Preliminary results of interstitial motexafin lutetium‐mediated PDT for prostate cancer
Authors: Du K.L. , Mick R. , Busch T.M. , Zhu T.C. , Finlay J.C. , Yu G. , Yodh A.G. , Malkowicz S.B. , Smith D. , Whittington R. , Stripp D. , Hahn S.M. 
Published: June 2006

AbstractBackground and ObjectivesInterstitial photodynamic therapy (PDT) is an emerging modality for the treatment of solid organ disease. Our group at the University of Pennsylvania has performed extensive studies that demonstrate the feasibility of interstitial PDT for prostate cancer. Our preclinical and clinical experience is herein detailed.Study Design/Materials and MethodsWe have treated 16 canines in preclinical studies, and 16 human subjects in a Phase I study, using motexafin lutetium‐mediated PDT for recurrent prostate adenocarcinoma. Dosimetry of light fluence, drug level and oxygen distribution for these patients were performed.ResultsWe demonstrate the safe and comprehensive treatment of the prostate using PDT. However, there is significant variability in the dose distribution and the subsequent tissue necrosis throughout the prostate.ConclusionsPDT is an attractive option for the treatment of prostate adenocarcinoma. However, the observed variation in PDT dose distribution translates into uncertain therapeutic reproducibility. Our future focus will be on the development of an integrated system that is able to both detect and compensate for dose variations in real‐time, in order to deliver a consistent overall PDT dose distribution. Lasers Surg. Med. 38:427–434, 2006. © 2006 Wiley‐Liss, Inc.
Novel Polymerizable Sulfur‐Containing Benzophenones as Free‐Radical Photoinitiators for Photopolymerization
Authors: Wang Hongyu , Wei Jun , Jiang Xuesong , Yin Jie 
Published: June 2006

AbstractSummary: Three novel polymerizable sulfur‐containing benzophenone photoinitiators, MAATPBP, CMAATPBP and BMAATPBP, were synthesized. These novel photoinitiators possess strongly red‐shifted maximum UV absorption and very weak fluorescence emission. The photopolymerization of two monomers with different functionality, bifunctional HDDA and trifunctional TMPTA, initiated by these three polymerizable photoinitiators, was studied by photo‐DSC using the unsaturated tertiary amine DMAEMA as the coinitiator. The results show that all the polymerizable photoinitiators were highly efficient and different photoinitiators exhibited different behaviors towards different monomers: BMAATPBP was the most efficient for HDDA; MAATPBP was the most efficient for TMPTA. They could also efficiently initiate the photopolymerization without the coinitiator because of photolysis at the CS bond.Structures of the polymerizable sulfur‐containing photoinitiators synthesized.magnified imageStructures of the polymerizable sulfur‐containing photoinitiators synthesized.