bluuebunny/crossref_metadata_2025_split huggingface dataset:
استخدام التحليل العنقودي لدراسة واقع التعليم الالكتروني في ظل جائحة كورونا على طلبة المعهد التقني نينوى
Authors: طه Ammar 
Published: February 2024

يعتبر التعليم الالكتروني احد الوسائل المهمة الذي افرزته ظروف الوباء الخطير لجائحة كورونا والذي تم تطبيقه على جميع الجامعات العراقية والعربية والعالمية لتفادي انتشار هذا المرض الخطير الذي فتك بالبشرية جميعا , ومن هذا المنطلق من المهم دراسة واقع التعليم الالكتروني والدراسة الالكترونية على الطلاب واستخدام النظريات الاحصائية والدراسات الاحصائية لدراسة هذا الواقع الذي سوف يصبح واقعيا بالاستخدام في السنوات القادمة .
ومن ضمن نظريات الاحصاء هو التحليل العنقودي فانه من المواضيع المهمة وقد تم توزيع استمارة استبيان على طلبة المعهد التقني نينوى ( في الجامعة التقنية الشمالية وقد شملت البيانات محورين هما اداء الامتحان والامتحان الالكتروني نفسة وكان عدد العينة 130 طالب وطالبة وبعد تفريغ البيانات كانت 11 استبانة تالفة وتم استخلاص النتائج وتبين زيادة قابلية الطلبة على استخدام واقع التعليم الالكتروني وزيادة المهارات والقابليات على استخدام وسائل التعليم الحديثة والانترنت .
Student’s Perception Of Using Duolingo As An English Learning Application
Authors: Hadina Nurul , Sari Mezia Kemala , Yoni Efri 
Published: February 2024

This study proposes to find out the student perception toward the use of Duolingo as an English learning application, Duolingo as a motivation tool to increase their motivation for learning English, and aspects of language that can be improved by language skill practice items on Duolingo. This study was quantitative research by using questioner as the data collection technique. This study was conducted on August 16, 2021, with the ninth-grade students at SMP Muhammadiyah Padang Panjang. The sample of this study consists of 16 students. The result showed that a lot of students gave a positive response to their experience using Duolingo based on the questionnaire. Duolingo is useful and helpful and it brings motivational benefits for students in English learning. Moreover, it shows that they easily master the fourth language skills and even practice their English in their daily life. Duolingo provides many uses for students as an English learning application. The use of Duolingo can help students learn English interestingly and make the learning process more enjoyable. Therefore, the use of Duolingo is recommended for English learning to help students improve their language learning abilities.
Abstrak
Penelitian ini bertujuan untuk mengetahui persepsi siswa terhadap penggunaan Duolingo sebagai aplikasi pembelajaran bahasa Inggris, Duolingo sebagai alat motivasi untuk meningkatkan motivasi belajar bahasa Inggris dan aspek bahasa yang dapat ditingkatkan dengan item latihan keterampilan bahasa di Duolingo. Penelitian ini merupakan penelitian kuantitatif dengan menggunakan kuesioner sebagai teknik pengumpulan data. Penelitian ini dilaksanakan pada tanggal 16 Agustus 2021 pada siswa kelas IX SMP Muhammadiyah Padang Panjang. Sampel penelitian ini berjumlah 16 siswa. Hasil penelitian menunjukkan bahwa banyak siswa yang memberikan respon positif terhadap pengalaman mereka menggunakan Duolingo berdasarkan kuisioner yang disebar. Duolingo bermanfaat, membantu dan dapat memotivasi siswa dalam belajar bahasa Inggris. Selain itu, hasil penelitian menunjukkan bahwa mereka dengan mudah menguasai keempat keterampilan bahasa dan bahkan mempraktekkan bahasa Inggris mereka dalam kehidupan sehari-hari. Duolingo memberikan banyak kegunaan bagi siswa sebagai aplikasi pembelajaran bahasa Inggris. Penggunaan Duolingo dapat membantu siswa untuk belajar bahasa Inggris dengan cara yang menarik dan membuat proses belajar menjadi lebih menyenangkan.Oleh karena itu, penggunaan Duolingo direkomendasikan untuk pembelajaran bahasa Inggris untuk membantu siswa meningkatkan kemampuan belajar bahasa mereka.
Early-stage hepatocellular carcinoma screening in patients with chronic hepatitis B in China: a cost–effectiveness analysis
Authors: Nan Yuemin , Garay Osvaldo Ulises , Lu Xianzhong , Zhang Yue , Xie Li , Niu Zhongyi , Chen Wen 
Published: February 2024

Aim:
To evaluate the cost–effectiveness of seven screening strategies for chronic hepatitis B (CHB) patients in China.
Methods:
A discrete event simulation model combining a decision tree and Markov structure was developed to simulate a CHB cohort aged ≥40 years on a lifetime horizon and evaluate the costs and health outcomes (quality-adjusted life years [QALYs] gained) of ultrasonography (US), alpha-fetoprotein (AFP), protein induced by vitamin K absence-II (PIVKA-II), AFP+US, AFP+PIVKA-II, GAAD (a diagnostic algorithm based on gender and age combined with results of AFP and PIVKA-II) and GAAD+US. Epidemiologic, clinical performance, utility and cost data were obtained from the literature, expert interviews and real-world data. Uncertainties on key parameters were explored through deterministic and probabilistic sensitivity analyses (DSA and PSA).
Results:
Compared with other strategies, GAAD+US detected the most HCC patients at early stage, and GAAD was the screening strategy with the lowest average cost per HCC case diagnosed. Using 3× China's 2022 GDP per capita ($38,233.34) as the threshold, the three strategies of US, GAAD and GAAD+US formed a cost–effectiveness frontier. Screening with US, GAAD, or GAAD+US was associated with costs of $6110.46, $7622.05 and $8636.32, and QALYs of 13.18, 13.48 and 13.52, respectively. The ICER of GAAD over US was $4993.39/QALY and the ICER of GAAD+US over GAAD was $26,691.45/QALY, which was less than 3× GDP per capita. Both DSA and PSA proved the stability of the results.
Conclusion:
GAAD+US was the most cost-effective strategy for early HCC diagnosis among CHB patients which could be considered as the liver cancer screening scheme for the high-risk population in China.
Theodor Mintrops komische Märchen in Bildern (1855-1866) / Theodor Mintrop's comic fairy tales in pictures (1855-1866)
Authors: Rose Margaret A. 
Published: February 2024

Theodor Mintrop’s posthumously published “fairy tale in 70 pictures”, König Heinzelmann’s Liebe (“King Heinzelmann’s Love”), of 1875 is based on drawings of 1866 that are in their turn based on pictures for Anna Rose (1839-1886) of 1855 and 1860. All of the drawings are illustrated here in colour and in a large format and are accompanied by commentaries in German and English. Like the drawings for Minna Bozi, née Rose, of 1855-1857, these works are characterised by Mintrop’s playful as well as artistically innovative humour.

Theodor Mintrops 1875 posthum veröffentlichtes „Märchen in 70 Bildern“, König Heinzelmann’s Liebe, basiert auf Zeichnungen von 1866, die ihrerseits auf Bilder für Anna Rose (1839-1886) von 1855 und 1860 zurückgehen. Alle Zeichnungen werden hier farbig und in einem großen Format abgebildet und von deutschen und englischen Kommentaren begleitet.
XÂY DỰNG VÀ THẨM ĐỊNH QUY TRÌNH ĐỊNH LƯỢNG TẠP ETHYL-(E/Z)-3-(2-CARBETHOXY-2-CYANOETHENYL) AMINO-1HPYRAZOL-4-CARBOXYLAT CÓ KHẢ NĂNG GÂY ĐỘT BIẾN GEN CỦA ALLOPURINOL BẰNG PHƯƠNG PHÁP LC-MS/MS
Authors: Lữ Thiện Phúc , Trần Hà Thái Châu , Nguyễn Uy Khang , Tạ Trung Tín , Kim Thị Thu Trinh , Trần Việt Hùng , Trương Ngọc Tuyền 
Published: February 2024

Đặt vấn đề: Hướng dẫn ICH M7(R1) về giới hạn tạp chất có khả năng gây độc tính hoặc đột biến gen bắt buộc kiểm tra nghiêm ngặt so với Dược điển vì ảnh hưởng hiệu quả điều trị lâm sàng và tính an toàn của thuốc với bệnh nhân. Do đó kiểm tra chất lượng nguyên liệu cũng như thành phẩm thuốc, đặc biệt thuốc nằm trong danh mục thuốc thiết yếu hiện hành lần VII của Việt Nam như allopurinol và tạp F liên quan bằng kỹ thuật có độ nhạy cao LC-MS/MS là xu hướng và cấp thiết. Mục tiêu nghiên cứu: Xây dựng và thẩm định quy trình định lượng Ethyl-(E/Z)-3-(2carbethoxy-2-cyanoethenyl)amino-1H-pyrazol-4-carboxylat của allopurinol theo hướng dẫn ICH M7(R1) về tạp có khả năng gây đột biến gen bằng phương pháp LC-MS/MS. Đối tượng và phương pháp nghiên cứu: Tạp Ethyl-(E/Z)-3-(2-carbethoxy-2-cyanoethyl)amino-1H- pyrazol-4-carboxylat (tạp F theo USP standard 2023) của allopurinol, xây dựng và thẩm định quy trình định lượng bằng LC-MS/MS theo hướng dẫn ICH Q2(R2); ICH M7(R1) và EC-657/2002. Kết quả: Điều kiện sắc ký: cột sắc ký Phenomenex Gemini NX C18 (150 mm x 4,6 x 5 µm) ở nhiệt độ 25˚C, pha động gồm acetonitril - nước acid formic 0,05% (85:15) theo chương trình isocratic, thể tích tiêm mẫu 10 µL, tốc độ dòng 0,8 mL/phút. Chất phân tích phát hiện bằng detector MS/MS; ion phân tử ban đầu→ion định lượng có m/z: 279,10→233,00. Thẩm định quy trình theo hướng dẫn ICH và EC-657/2002: quy trình đạt độ đặc hiệu – chọn lọc; đường chuẩn tuyến tính trong khoảng nồng độ 3 - 100 ppb và hệ số tương quan là 0,997; giới hạn phát hiện thấp từ 1 - 3 ppb; giới hạn định lượng 3 ppb; độ đúng đạt tỷ lệ hồi phục từ 99,30 - 101,37% , độ chính xác đạt yêu cầu RSD < 2%. Kết luận: Đã xây dựng và thẩm định quy trình định lượng tạp Ethyl-(E/Z)-3-(2-carbethoxy-2-cyanoethenyl)amino-1H-pyrazol-4-carboxylat của allopurinol bằng phương pháp LC-MS/MS.
EVALUATION OF SURGICAL OUTCOMES OF OSTEOPOROTIC VERTEBRAL COMPRESSION FRACTURE PATIENTS TREATED BY KYPHOPLASTY, AT MILITARY HOSPITAL 105
Authors: Nguyen Thanh Bac  , Dao Van Thuy  
Published: February 2024

Purpose: To evaluate the surgical outcomes of osteoporotic vertebral fracture patients treated by kyphoplasty at Military Hospital 105.
Subjects and Methods: A descriptive, retrospective study of 34 osteoporotic fractures patients who were treated by kyphoplasty at Military Hospital 105 from January 2021 to December 2021.
Results: Immediately post operation, 100% of patients had significant pain relief compared to preoperation (average VAS score after surgery 1.91 ± 1.22); 100% of patients had vertebral body height restored (with moderate level 36.4%, good level 39.4%); The kyphosis corrected spine has statistical significance compared to before treatment (with p < 0.05).
"O caminho se faz caminhando": experiência de integrantes de uma liga de saúde mental
Authors: Oliveira Eliany Nazaré , Pinto Aline Maria Melo , Rodrigues Caio San , Silva Lídia Cristina Monteiro da , Silva Emília Nascimento , França Sabrina da Silva , Oliveira Flávia Regino , Nascimento Ravena Silva do 
Published: February 2024

Objetivou-se relatar a vivência de estudantes que participaram da Liga Interdisciplinar em Saúde Mental. Trata-se de relato de experiência realizado com 35 estudantes que participaram da Liga. Os depoimentos foram organizados em cinco categorias de análise: experiências vivenciadas pelos integrantes da Liga; potências das ligas acadêmicas no processo de formação; articulação entre os três eixos do tripé universitário: extensão, ensino e pesquisa; desenvolvimento de habilidades sociais e emocionais e impasses e limitações do projeto. Os ligantes explanaram desde o aprendizado aprofundado sobre saúde mental até as vivências por meio das extensões da Liga com a comunidade. Os relatos expressam grande desenvolvimento acadêmico, com aquisição de habilidades e competências construídas a partir do ensino, da pesquisa e extensão. Conclui-se que as ligas acadêmicas contribuem de forma efetiva para formação e qualificação dos futuros profissionais.
The Impact of Implementing Value-Added Tax on the Islamic Banking Practices
Authors: Alkhayyal Raneem AbdulAziz Abdullah , Parveen Rehana 
Published: February 2024

The main aim of this research is to determine the impact of implementing VAT on Islamic banking practices. Prohibition of Riba (interest) and Gharar (uncertainty) are the fundamental principles of Islamic banking and key differentiators to differentiate it from conventional banking practices. It was found that Riba and Gharar are the two main hindrances for the Islamic banks operating in Saudi Arabia, as these two are not endorsed by existing Sharia principles. As a result, the Islamic banks in the country leveraged Mudarabah to invest in asset development, which is supported by Sharia principles. On the other hand, rising interest rates, influenced by VAT implementation that caused a rise in commodity prices as well, led to consumers seeking less loan support. In contrast, it increased the money deposit volume of consumers. With the development of a compliance team, the Islamic banks in the country are recommended not only to enforce the practice of Standard operation procedure (SOPs ) but also to start a fee-based structure that is endorsed by Sharia principles, and it would also help banks to accumulate VAT collections through fees from customers.
Spinoza On the Knowledge of God and The Existence of Evil in The World: An Epistemic Purview
Authors: Sunday Agama Christian , John Ezenwankwor , Victor Obiagwu Obinna , Ikechukwu Ozoigbo Bonaventure 
Published: February 2024

This study examines Spinoza’s position on the knowledge of God and the problem of evil in the world. Drawing from Spinoza’s argument that there is nothing like evil in the world since all finite beings are logically necessary modification of the divine substance, this paper contends that Spinoza did not only fail in solving the problem of evil but also contradicted himself and made it appear more complex. This problem cannot be easily solved either by philosophy or theology because of the complexities in the nature of evil. In both cases, it is impossible to deny the existence of evil as well as to fathom the ontological possibility of evil in the world.
Structural and Compositional Changes of Bamboo Fibers During Super-Heated Steam Treatment Improved Mechanical Properties of Polypropylene/Bamboo Biocomposite
Authors: Yamashiro Keisaku , Nishida Haruo 
Published: February 2024

Structural and compositional changes of bamboo fibers, which were prepared through super-heated steam (SHS) treatment at normal pressure and fine grinding, were investigated by infra-red spectroscopy, thermogravimetry, viscosity-average molecular weight (Mv) measurement, and X-ray fluorescence analysis. SHS-treated Moso bamboo resulted in preferential decomposition of hemicellulose without any decrease in the Mv of cellulose crystalline. The SHS-treated bamboo was easily ground to obtain various short bamboo fibers (sBF) suitable for conventional melt processing of composites with polypropylene. The sBF showed good melt-processability and contributed to the mechanical performance of the composites moldings, resulting in 290% increases in flexural modulus.
Keywords: Moso bamboo, superheated steam treatment, short bamboo fiber, chemical composition
Clarification of Glucose from Cellulose Hydrolysate by Ultrafiltration with Polyethersulfone Membrane
Authors: Md Zain Masniroszaime , Mohammad Abdul Wahab 
Published: February 2024

Ultrafiltration was used to clarify glucose from cellulose hydrolysate using polyethersulfone (PES) membrane. The flux behavior of PES membrane was studied in concentrating glucose from cellulose hydrolysate during dead end ultrafiltration in different pH of solutions and Kumar’s model was applied to analyse the fouling mechanism. The permeation of glucose achieved more than 93% for all the different pH solution. The permeate flux decreased over time as a result of membrane fouling. The minimum fouling was obtained at pH solution above the IEP due to protein-protein and membrane-protein repulsions alleviating aggregation and fouling. Cake formation blocking was identified as the dominant mechanism for flux decline.
Keywords: glucose, enzyme hydrolysis, lignocellulosic biomass, ultrafiltration, polyethersulfone
Hydrogen Production by Anaerobic Digestion of Crude Glycerol from Biodiesel Fuel Manufacturing Process – Part II. Effects of Biodiesel Fuelrelated Chemical Components on Hydrogen Production
Authors: Yamane Oozora , Komiyama Masaharu 
Published: February 2024

In order to utilize crude glycerol, a byproduct from biodiesel fuel production, its conversion through anaerobic fermentation was studied. Chemical components related to biodiesel fuel production were examined as substrates of anaerobic digestion. Glycerol was found to play a key role for the hydrogen production, while methanol, KOH and waste vegetable oil from which biodiesel fuel was made exerting synergetic effects.
Keywords: Biodiesel fuel, Crude glycerol, Anaerobic digestion, Hydrogen fermentation, Biodiesel fuel-related chemicals
PENDAMPINGAN KETERAMPILAN DIGITALISASI PEMASARAN MELALUI MEDIA SOSIAL INSTAGRAM GUNA MENINGKATKAN EKSISTENSI MUA ROFISURONO KLATEN
Authors: Fardani Fikrina Faraidi 
Published: February 2024

MUA merupakan sebuah bisnis yang unik karena menjual jasa secara custom. Setiap pengguna jasa akan memiliki preferensi riasan yang berbeda-beda, sehingga para pelaku usaha harus dapat menyesuaikan dengan apa yang diharapkan konsumen. Mitra pengabdian masyarakat ini adalah MUA Rofisurono yang berasal dari Klaten. Fokus kegiatan ini adalah melakukan pendampingan keterampilan pemasaran media sosial. Adanya portofolio digital yang baik akan mempermudah konsumen untuk mendapatkan gambaran tentang apa yang akan didapatkannya kelak. Portofolio ini dapat diorganisir melalui media sosial, salah satunya Instagram. Tujuan kegiatan ini adalah meningkatkan pemahaman dan pengetahuan terkait branding dan strategi promosi untuk keberlangsungan usaha MUA. Metode pelaksanaan kegiatan dilakukan dalam beberapa tahap, yaitu (1) observasi, (2) wawancara dan diskusi, (3) sosialisasi dan edukasi terkait media sosial, dan (4) pendampingan pengelolaan Instagram. Hasil dari kegiatan ini diharapkan mampu meningkatkan eksistensi MUA Rofisurono yang menjangkau minat dan ketertarikan konsumen lebih luas lagi. Selain itu, diharapkan mempermudah konsumen untuk mengenal MUA Rofisurono dan dapat memilih riasan mana yang cocok untuk dirinya karena portofolio digital yang sudah disusun dengan baik melalui Instagram.
Pulmonary Involvement during Varicella in a Patient with Sickle Cell Disease: Diagnosis and Treatment
Authors: Thioub Daouda , Sarr Ndeye Amy , Kogwapa Christine Amengo , Mbaye Khardiata Diallo , Lakhe Ndeye Aïssatou , Badiane Aboubakar Sidikh , Ka Daye , Fall Ndeye Maguette , Cisse Viviane Marie Pierre , Seydi Moussa 
Published: February 2024

Introduction: Pulmonary involvement during chickenpox is one of the most serious complications. However, it can be difficult to distinguish between varicella pneumonia, bacterial superinfection and an acute chest syndrome. We report a case of varicella complicated by pneumonia in a young adult with sickle cell disease.
Observation: It was a 24-year-old woman with sickle cell disease. Examination on admission revealed generalized skin lesions of varying ages, associated with scratching lesions. On day 3 of hospitalization, she presented an acute respiratory distress associated with fever (40°C). Thoracic CT angiography revealed diffuse pulmonary nodules and micronodules in both lung fields. Blood culture isolated Staphylococcus spp. The patient was put on oxygen therapy combined with antiviral treatment and antibiotic therapy. The course was marked by symptoms regression, with disappearance of respiratory distress on day 2 and apyrexia on day 3 of treatment. The follow-up chest CT scan carried out at month 4, came back normal.
Conclusion: Although pneumonia is one of the most common complications of varicella, it can be difficult to diagnose in patients with sickle cell disease, considering the frequency of pulmonary involvement of various etiologies
Impact of Organic Manures and Inorganic Fertilizers on Growth, Yield and it’s Attributing Traits of Chilli (Capsicum annum L.)
Authors: Chitla Sreeja Reddy , Dayal Abhinav , Dileep Retineni 
Published: February 2024

The experiment was carried out to explore the “Impact of organic manures and inorganic fertilizers on growth, yield and it’s attributing traits on Chilli (Capsicum annum L.)”. The experiment was conducted during 2021-2022 at experimental farm of Department of Horticultural sciences, Naini Agriculture Institute, Prayagraj, Uttar Pradesh. Recommended Dose of Fertilizers (RDF), vermicompost, poultry manure, farm yard manure and inorganic fertilizers were used as treatments. Eight different doses of treatments were recommended for each replication. Experiment was conducted using Randomized Block Design (RBD). The performance of growth and yield was analysed. The Treatment T4 - 100%RDF+ (5t vermicompost +2.5t poultry manure) performed well with a better Plant height of 77 cm at 90 days, number of branches 15.32, days to 50 % flowering 36.32 days, number of fruits per plant 75.32, fruit length 11.64cm, number of seeds per fruit 62.66, test weight of 6.68 g, maximum fruit yield per plant was 845.80 g and maximum fruit yield per plot was 313.25 q/ha. Control treatment shown the lowest growth and yield.
Polyphenol galangin induces the ROS and ER stress-mediated intrinsic and extrinsic apoptotic pathways towards human colon carcinoma HCT-116 cells
Authors: Wang Bo , Fu Xin , Liu Li-Li , Wu Fei-Fei , Zhao Xin-Huai 
Published: February 2024

A natural anti-oxidant galangin, a flavonoid compound rich in the root of galangal, has been proved to exert anti-proliferation and apoptosis induction towards various cancer cells. However, its activities and molecular mechanism against colorectal cancer cell lines (e.g. HCT-116) is still unclear. The aim of this study was to reveal the inhibition and apoptosis induction of galangin in the HCT-116 cells. The results of CCK-8 assay demonstrated that galangin at 20-160 μmol/L inhibited the HCT-116 cells growth in a dose-time-dependent manner. Galangin changed cell morphology, arrested cell cycle at G0/G1 phase, decreased mitochondrial membrane potential, increased intracellular reactive oxygen species (ROS) and Ca2+ and induced early apoptosis in the HCT-116 cells. Based on western blotting results, on one hand, galangin at 80-160 μmol/L up-regulated pro-apoptotic proteins expression such as AIF, PIG3, and Bax, and induced mitochondrial pathway by up-regulating the levels of cleaved caspase-8, cleaved caspase-7, cleaved caspase-9 and cleaved caspase-3, as well as cleavage of poly (ADP-ribose) polymerase (PARP). On the other hand, galangin also induced endoplasmic reticulum (ER) stress in the cell via up-regulation of CHOP and DR5 and then activation of caspase cascades. The results illustrated that galangin induced apoptosis towards the HCT-116 cells through the ROS- and ER stress-mediated both intrinsic and extrinsic apoptotic pathways.
KEYWORDS: galangin; human colon carcinoma cells; apoptotic mechanism; reactive oxygen species; endoplasmic reticulum stress
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