bluuebunny/crossref_metadata_2025_split huggingface dataset:
Mechanism of decrease of oral bioavailability of cyclosporin A during immunotherapy upon coadministration of amphotericin B
Authors: Ishizaki Junko , Ito Satsuki , Jin Mingji , Shimada Tsutomu , Ishigaki Tamae , Harasawa Yukiko , Yokogawa Koichi , Takami Akiyoshi , Nakao Shinji , Miyamoto Ken‐ichi 
Published: January 2008

AbstractThe trough level of blood concentration of cyclosporin A (CyA) in a patient receiving immunotherapy was observed to decrease following coadministration of amphotericin B (AMB). This clinical observation was confirmed experimentally in Wistar rats intravenously given AMB (1.5 or 3.0 mg/kg) or saline (control) for 4 days, followed by CyA (10 mg/kg). The blood concentration of CyA after i.v. or p.o. administration in both AMB groups was significantly decreased compared with the control. The oral bioavailability of CyA after 1.5 or 3.0 mg/kg AMB treatment was decreased to 67% or 46%, respectively, of that of the control group. AMB treatment increased the expression levels of mdr1a and mdr1b mRNAs in the duodenum to about three times the control, and expression of CYP3A2 mRNA in the liver was increased to about twice the control. The P‐gp and CYP3A2 proteins were increased significantly. These findings suggest that the oral bioavailability of CyA is reduced as a result of both increased efflux transport via P‐glycoprotein in the duodenum and an increased first‐pass effect of CYP3A2‐mediated hepatic metabolic activity, induced by AMB. It is suggested that careful monitoring of CyA levels is necessary in the event of AMB administration to patients receiving immunotherapy with CyA. Copyright © 2008 John Wiley & Sons, Ltd.
Posterior urethral valves in three siblings: A case report and review of the literature
Authors: Schreuder Michiel F. , van der Horst Henricus J. R. , Bökenkamp Arend , Beckers Goedele M. A. , van Wijk Joanna A. E. 
Published: January 2008

AbstractBACKGROUND:Posterior urethral valves (PUVs), the most common congenital cause of lower urinary tract obstruction, have been described to occur in families. Until now, reports have been published on 10 cases of PUVs in two siblings and 13 cases of PUVs in identical and nonidentical twins, of which we provide an overview.CASES:We report for the first time on three siblings with PUVs, with a different presentation and course in the three brothers. This within‐family variability is well noted and is even present in identical twins.CONCLUSIONS:This finding suggests that both genetic and environmental factors play a role in the presence and severity of PUVs. As brothers of patients with PUVs seem to be at increased risk of having PUVs, we suggest antenatal ultrasound screening in brothers of patients with PUVs in order to guide early and optimal care. Birth Defects Research (Part A), 2008. © 2008 Wiley‐Liss, Inc.
Non‐Thermal effects in the microwave induced unfolding of proteins observed by chaperone binding
Authors: George Doaa F. , Bilek Marcela M. , McKenzie David R. 
Published: January 2008

AbstractWe study the effect of microwaves at 2,450 MHz on protein unfolding using surface plasmon resonance sensing. Our experimental method makes use of the fact that unfolding proteins tend to bind to chaperones on their unfolding pathway and this attachment is readily monitored by surface plasmon resonance. We use the protein citrate synthase (CS) for this study as it shows strong binding to the chaperone alpha crystallin when stressed by exposure to excess temperature. The results of microwave heating are compared with the effect of ambient heating and a combination of ambient and microwave heating to the same final temperature. We study the temperature distributions during the heating process. We show that microwaves cause a significantly higher degree of unfolding than conventional thermal stress for protein solutions heated to the same maximum temperature. Bioelectromagnetics 29:324–330, 2008. © 2008 Wiley‐Liss, Inc.
Is fertility reduced among men exposed to radiofrequency fields in the Norwegian Navy?
Authors: Møllerløkken Ole J. , Moen Bente E. 
Published: January 2008

AbstractThe effects of radiofrequency fields on human health are not well understood, and public concern about negative health effects has been rising. The aim of this study was to examine the relationship between workers exposed to electromagnetic fields and their reproductive health. We obtained data using a questionnaire in a cross‐sectional study of naval military men, response rate 63% (n = 1487). We asked the respondents about exposure, lifestyle, reproductive health, previous diseases, work and education. An expert group categorized the work categories related to electromagnetic field exposure. We categorized the work categories “tele/communication,” “electronics” and “radar/sonar” as being exposed to electromagnetic fields. Logistic regression adjusted for age, ever smoked, military education, and physical exercise at work showed increased risk of infertility among tele/communication odds ratio (OR = 1.72, 95% confidence interval 1.04–2.85), and radar/sonar odds ratio (OR = 2.28, 95% confidence interval 1.27–4.09). The electronics group had no increased risk. This study shows a possible relationship between exposure to radiofrequency fields during work with radiofrequency equipment and radar and reduced fertility. However, the results must be interpreted with caution. Bioelectromagnetics 29:345–352, 2008. © 2008 Wiley‐Liss, Inc.
Electrical properties of acupuncture points and meridians: A systematic review
Authors: Ahn Andrew C. , Colbert Agatha P. , Anderson Belinda J. , Martinsen Ørjan G. , Hammerschlag Richard , Cina Steve , Wayne Peter M. , Langevin Helene M. 
Published: January 2008

AbstractAccording to conventional wisdom within the acupuncture community, acupuncture points and meridians are special conduits for electrical signals. This view gained popularity after anecdotal reports and clinical studies asserted that these anatomical structures are characterized by lower electrical impedance compared to adjacent controls. To ascertain whether evidence exists to support or refute this claim, we conducted a systematic review of studies directly evaluating the electrical characteristics of acupuncture structures and appropriate controls. We searched seven electronic databases until August 2007, hand‐searched references, and consulted technical experts. We limited the review to primary data human studies published in English. A quality scoring system was created and employed for this review. A total of 16 articles representing 18 studies met inclusion criteria: 9 examining acupuncture points and 9 examining meridians. Five out of 9 point studies showed positive association between acupuncturepointsand lower electrical resistance and impedance, while 7 out of 9 meridian studies showed positive association between acupuncturemeridiansand lower electrical impedance and higher capacitance. The studies were generally poor in quality and limited by small sample size and multiple confounders. Based on this review, the evidence does not conclusively support the claim that acupuncture points or meridians are electrically distinguishable. However, the preliminary findings are suggestive and offer future directions for research based on in‐depth interpretation of the data. Bioelectromagnetics 29:245–256, 2008. © 2008 Wiley‐Liss, Inc.
Cellular Origin of Dysiherbaine, an Excitatory Amino Acid Derived from a Marine Sponge
Authors: Sakai Ryuichi , Yoshida Kazufumi , Kimura Atsuko , Koike Kanae , Jimbo Mitsuru , Koike Kazuhiko , Kobiyama Atsushi , Kamiya Hisao 
Published: January 2008

AbstractThe cellular origin of dysiherbaine, a marine‐sponge toxin, was investigated immunohistochemically by using an anti‐dysiherbaine antibody. Dysiherbaine‐like immunoreactivity was found to be localized in spherical cells harbored in the sponge mesohyl. A combination of ribosomal RNA gene (rDNA) analysis and cell‐morphology analysis revealed that the spherical cells wereSynechocystiscyanobacteria. However, the sponge, identified asLendenfeldia chondrodeson the basis of its rDNA sequence, appeared to contain two different chemotypes—dysiherbaine‐producing (DH+) and nondysiherbaine‐producing (DH−)—both of which inhabited the same region.Synechocystiscells in the DH−sponge were not labeled with antibody, although the 16S rDNA gene profile of the cyanobacteria in the DH−sponge was indistinguishable from that of the cyanobacteria in the DH+sponge. On the basis of these results, we hypothesize that dysiherbaine is a metabolite of certain varieties of endosymbioticSynechocystissp.
Ruthenium Carbene Complexes Bearing an Anionic Carboxylate Chelated to a Hemilabile Ligand
Authors: Samec Joseph S. M. , Grubbs Robert H. 
Published: January 2008

AbstractA series of bidentate ruthenium‐based NHC complexes with the general formula [(H2IMes)(κ2‐L‐COO)ClRuCHPh)], where L is either PAr3, HNR2, or ROR, were prepared from commercially available [(H2IMes)(PCy3)Cl2Ru(CHPh)] (2) and the appropriate ligand. The catalytic activities of the complexes were evaluated in ring‐closing metathesis reactions. The type of donor ligand has a major impact on both the initiation behavior and also the stability of the complexes. Upon addition of CuCl to the reaction mixture the initiation is improved for the phosphine or amine containing chelates. For the P,O‐chelate, the fast initiation was followed by decomposition. In the case of the N,O‐containing chelate, a stable catalytic system was achieved. Trapping experiments support that the nitrogen lone‐pair reversibly coordinates CuCl during the reaction.
Preparation and Characterization of a Microcrystalline Non‐Heme FeIII(OOH) Complex Powder: EPR Reinvestigation of FeIII(OOH) Complexes—Improvement of the Perturbation Equations for the g Tensor of Low‐Spin FeIII
Authors: Martinho Marlène , Dorlet Pierre , Rivière Eric , Thibon Aurore , Ribal Caroline , Banse Frédéric , Girerd Jean‐Jacques 
Published: January 2008

AbstractThe first example of a microcrystalline powder of a synthetic low‐spin (LS) mononuclear FeIII(OOH) intermediate has been obtained by the precipitation of the [FeIII(L52)(OOH)]2+ complex at low temperature. The high purity of this thermally unstable powder is revealed by magnetic susceptibility measurements. EPR studies on this complex, in the solid state and also in frozen solution, are reported and reveal the coexistence of two related FeIII(OOH) species in both states. We also present a theoretical analysis of the g tensor for LS FeIII complexes, based on new perturbation equations. These simple equations provide distortion‐energy parameters that are in good agreement with those obtained by a full‐diagonalization calculation.
ChemInform Abstract: Computational Study of the Zr4+ Tetranuclear Polymer, [Zr4(OH)8(H2O)16]8+
Authors: Rao Niny , Holerca Marian N. , Klein Michael L. , Pophristic Vojislava 
Published: January 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Three Hexafluoridoiridates(IV), Ca[IrF6]×2H2O, Sr[IrF6]×2H2O and Ba[IrF6].
Authors: Smolentsev Anton I. , Gubanov Alexander I. , Danilenko Andrey M. 
Published: January 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Unusual Coexistence of Magnetic and Nonmagnetic Mo6 Octahedral Clusters in a Chalcohalide Solid Solution: Synthesis, X‐Ray Diffraction, EPR, and DFT Investigations of Cs3Mo6Ii6I i2‐xSeixIa6 .
Authors: Kirakci Kaplan , Cordier Stephane , Shames Alex , Fontaine Bruno , Hernandez Olivier , Furet Eric , Halet Jean‐Francois , Gautier Regis , Perrin Christiane 
Published: January 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Experimental Determination of the NH4NO3/ (NH4)2SO4/H2O Phase Diagram.
Authors: Bothe Jameson R. , Beyer Keith D. 
Published: January 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis and Structure of the New Complex Hydride Li2BH4NH2.
Authors: Chater Philip A. , David William I. F. , Anderson Paul A. 
Published: January 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Structural Units in Three Uranyl Perrhenates.
Authors: Karimova Oxana V. , Burns Peter C. 
Published: January 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Heterogeneous Vanadium Catalysts for Racemization and Chemoenzymatic Dynamic Kinetic Resolution of Benzylic Alcohols.
Authors: Wuyts S. , Wahlen J. , Jacobs P. A. , De Vos D. E. 
Published: January 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Iodine‐Catalyzed C‐ and O‐Nucleophilic Substitution Reactions of Aryl‐Propargyl Methanols.
Authors: Srihari P. , Bhunia Dinesh C. , Sreedhar P. , Mandal S. S. , Reddy J. Shyam Sunder , Yadav J. S. 
Published: January 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis of Novel Spiro Compounds Using Anthrone and Pyrazole‐5‐thione Moieties: A Michael Addition Approach.
Authors: Chande Madhukar S. , Khanwelkar Rahul R. , Barve Pravin A. 
Published: January 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Indium‐Catalyzed Cycloisomerization of ω‐Alkynyl‐β‐ketoesters into Six‐ to Fifteen‐Membered Rings.
Authors: Tsuji Hayato , Yamagata Ken‐ichi , Itoh Yoshimitsu , Endo Kohei , Nakamura Masaharu , Nakamura Eiichi 
Published: January 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Palladium‐Catalyzed Intramolecular 5‐endo—trig Oxidative Heck Cyclization: A Facile Pathway for the Synthesis of Some Sesquiterpene Precursors.
Authors: Ray Devalina , Paul Sunanda , Brahma Sulagna , Ray Jayanta K. 
Published: January 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: A Divergent Synthesis of γ‐Iminolactones, Dihydroquinolin‐2‐ones, and γ‐Lactames from β‐Hydroxymethylcyclopropanylamides.
Authors: Xiong Tao , Zhang Qian , Zhang Zhiguo , Liu Qun 
Published: January 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Conjugate Reduction of α,β‐Unsaturated Esters and Amides with Tributyltin Hydride in the Presence of Magnesium Bromide Diethyl Etherate.
Authors: Hirasawa Satomi , Tajima Yoshie , Kameda Yoko , Nagano Hajime 
Published: January 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Efficient Procedure for Chemoselective N‐Nitrosation of Secondary Amines with Trichloromelamine—NaNO2.
Authors: Bamoniri A. , Zolfigol M. A. , Mirjalili B. F. , Fallah F. 
Published: January 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: N‐Acetyl‐N,N‐dipyrid‐2‐yl (Cyclooctadiene) Rhodium (I) and Iridium (I) Complexes: Synthesis, X‐Ray Structures, Their Use in Hydroformylation and Carbonyl Hydrosilylation Reactions and in the Polymerization of Diazocompounds
Authors: Bantu Bhasker , Wurst Klaus , Buchmeiser Michael R. 
Published: January 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Studies on Novel Synthetic Methodologies. Part 154. Remarkably Mild and Efficient Catalytic Sakurai Reaction of N‐Alkoxycarbonylamino Sulfones with Allyltrimethylsilane Using Indium(III) Chloride.
Authors: Das Biswanath , Damodar Kongara , Saritha Darshanala , Chowdhury Nikhil , Krishnaiah Martha 
Published: January 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Simple Preparation of Symmetrical Carboxylic Acid Anhydrides by Means of Na2CO3/SOCl2.
Authors: Kazemi F. , Kiasat A. R. , Mombaini B. 
Published: January 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: An Efficient, Facile, and General Stereoselective Synthesis of Heterosubstituted Alkylidenecyclopropanes.
Authors: Masarwa Ahmad , Stanger Amnon , Marek Ilan 
Published: January 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Efficient Palladium(II) Catalysis under Air. Base‐Free Oxidative Heck Reactions at Room Temperature or with Microwave Heating.
Authors: Lindh Jonas , Enquist Per‐Anders , Pilotti Aake , Nilsson Peter , Larhed Mats 
Published: January 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Hydroamination of Cinnamyl Alcohol Using Lithium Amides.
Authors: Barry Conor S. , Simpkins Nigel S. 
Published: January 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis of Aliphatic Hydroxyaryl Ketones or (Hetero)aryl Hydroxyaryl Ketones by Acylation of Organometallic Reagents.
Authors: Katritzky Alan R. , Le Khanh N. B. , Mohapatra Prabhu P. 
Published: January 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Highly Efficient and Clean Method for Direct α‐Iodination of Aromatic Ketones.
Authors: Yin Guodong , Gao Meng , She Nengfang , Hu Shengli , Wu Anxin , Pan Yuanjiang 
Published: January 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Room‐Temperature Debenzylation of N‐Benzylcarboxamides by N‐Bromosuccinimide.
Authors: Kuang Liping , Zhou Jing , Chen Sheng , Ding Ke 
Published: January 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Selective Mono‐Fluorination of Diols via a Cyclic Acetal of N,N‐Diethyl‐4‐methoxybenzamide.
Authors: Suwada Mitsuhiro , Fukuhara Tsuyoshi , Hara Shoji 
Published: January 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.