bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effect of the closed‐loop hippocampal low‐frequency stimulation on seizure severity, learning, and memory in pilocarpine epilepsy rat model
Authors: Zare Meysam , Rezaei Mahmoud , Nazari Milad , Kosarmadar Nastaran , Faraz Mona , Barkley Victoria , Shojaei Amir , Raoufy Mohammad Reza , Mirnajafi‐Zadeh Javad 
Published: March 2024

AbstractAimsIn this study, the anticonvulsant action of closed‐loop, low‐frequency deep brain stimulation (DBS) was investigated. In addition, the changes in brain rhythms and functional connectivity of the hippocampus and prefrontal cortex were evaluated.MethodsEpilepsy was induced by pilocarpine in male Wistar rats. After the chronic phase, a tripolar electrode was implanted in the right ventral hippocampus and a monopolar electrode in medial prefrontal cortex (mPFC). Subjects' spontaneous seizure behaviors were observed in continuous video recording, while the local field potentials (LFPs) were recorded simultaneously. In addition, spatial memory was evaluated by the Barnes maze test.ResultsApplying hippocampal DBS, immediately after seizure detection in epileptic animals, reduced their seizure severity and duration, and improved their performance in Barnes maze test. DBS reduced the increment in power of delta, theta, and gamma waves in pre‐ictal, ictal, and post‐ictal periods. Meanwhile, DBS increased the post‐ictal‐to‐pre‐ictal ratio of theta band. DBS decreased delta and increased theta coherences, and also increased the post‐ictal‐to‐pre‐ictal ratio of coherence. In addition, DBS increased the hippocampal‐mPFC coupling in pre‐ictal period and decreased the coupling in the ictal and post‐ictal periods.ConclusionApplying closed‐loop, low‐frequency DBS at seizure onset reduced seizure severity and improved memory. In addition, the changes in power, coherence, and coupling of the LFP oscillations in the hippocampus and mPFC demonstrate low‐frequency DBS efficacy as an antiepileptic treatment, returning LFPs to a seemingly non‐seizure state in subjects that received DBS.
Institutional pressure and analyst behavior: Evidence from the financial sector
Authors: Liu Chang , Fan Maoyong , Athavale Manoj 
Published: March 2024

AbstractThis study examines the impact of employment background on the objectivity of profitability forecasts in the financial sector. We find that investment bank analysts provide relatively biased recommendations and less accurate forecasts than their counterparts at independent research firms (IRFs). The performance discrepancy is greater for bulge bracket banks and for firms involved in syndication with the analysts' employers. A closer look at analysts transitioning between IRFs and investment banks reveals that these biases stem from their affiliation with investment banks rather than personal bias. Our findings emphasize the critical influence of the work environment on analyst behavior.
Between global events and local reverberations: Globalization, local media framing and the 2014 FIFA World Cup
Authors: Petersen‐Wagner Renan , Lee Ludvigsen Jan Andre 
Published: March 2024

AbstractThis article advances sociological work on globalization processes. It concerns itself with conceptualizations of how the local and global ‘clash’, utilizing Ulrich Beck's work on globalization, cosmopolitanism and power. By employing Brazil's 2014 Fédération Internationale de Football Association (FIFA) men's World Cup as a case, this article seeks to build on Beck's theorizations, into the field of football; using the General Law of the World Cup as a symbolic representation for the global/local, interest‐driven interactions between Brazil and FIFA. In particular, this article is concerned with how FIFA's requirements, standards and norms, as imposed on the host nation, were framed within local media and journalistic discourses. The article extends Beck's insights by problematizing how global demands meet local socio‐spatial, legal and cultural contexts and how these demands, seeking to regulate and secure consumption, are resisted by various domestic and localized actors situated within a power game.
Predictors and concomitants of the remission of frequent headache in pediatrics: A longitudinal community study
Authors: Rau Lisa‐Marie , Humberg Clarissa , Könning Anna , Claus Benedikt B. , Stahlschmidt Lorin , Wager Julia 
Published: March 2024

AbstractObjectiveWe aimed to examine factors associated with frequent headache remission in schoolchildren aged 10–18 years.BackgroundFrequent headache is a common health problem in adolescence, and some individuals in this population experience remission. Factors preceding headache remission as opposed to ongoing headache, and their development over time, have not been examined extensively.MethodsData were derived from a large school sample (N = 2280). Over the course of 1 year, n = 156 adolescents experienced remission from frequent headaches, while n = 125 adolescents continued to have frequent headaches throughout the year. In this longitudinal case–control study, we predicted headache remission using demographic, pain, psychosocial, sleep, and physiological characteristics. Additionally, we sought to explore the development of psychosocial, sleep, and physiological characteristics in relation to remitted versus ongoing headache over the 1‐year period.ResultsA model containing the variables sex (odds ratio [OR] = 0.43, 95% confidence interval [CI] = 0.248–0.76, p = 0.003), headache intensity (OR = 0.85, 95% CI = 0.73–0.99, p = 0.035), anxiety score (OR = 0.92, 95% CI = 0.85–1.01, p = 0.071), and depression score (OR = 0.94, 95% CI = 0.89–1.00, p = 0.041) predicted the outcome variable (remitted vs. non‐remitted headache), explaining 17% of the variance in group membership. Schoolchildren reporting remitted headache at the end of the year exhibited lower depression (F[1, 557.01] = 45.77, p < 0.001) and anxiety scores (F[1, 557.01] = 21.72, p < 0.001), higher school satisfaction (F[1, 209.46] = 7.15, p = 0.008), and fewer difficulties falling asleep (F[1, 856.52] = 41.21, p < 0.001) or sleeping through the night (F[1, 731.12] = 26.42, p < 0.001) throughout the year compared to those with non‐remitted headache. Depression scores declined significantly over the year in the group with remitted headache, whereas these scores remained constant in the group with non‐remitted headache.ConclusionOur results suggest a correlation between headache remission and male sex, improved mental health, and reduced pain‐related burden. Moreover, there was an observed decline in symptoms of depression during headache remission. Psychotherapy may be a promising treatment strategy for addressing frequent headaches reported by children and adolescents.
Nlrp3 inflammasome drives regulatory T cell depletion to accelerate periapical bone erosion
Authors: Wang Konghuai , Liu Jiayi , Yue Junli , Zhou Lu , Mao Hanqing , Li Jiaqi , Sun Zhijun , Chen Zhi , Zhang Lu 
Published: March 2024

AbstractAimApical periodontitis is an inflammatory disorder triggered by an immune response to bacterial infection, leading to the periapical tissue damage and alveolar resorption. However, the underlying mechanisms driving this process remain elusive, due to the complex and interconnected immune microenvironment within the local lesion site. In this study, the influence of Nlrp3 inflammasome‐mediated immune response on the apical periodontitis was investigated.MethodologyRNA sequencing, immunohistochemistry and ELISA assay were performed to investigate the activation of Nlrp3 inflammasome signalling pathways in the human periapical tissues, including radicular cysts, periapical granulomas and healthy oral mucosa. A mouse model of apical periodontitis was established to study the role of Nlrp3 knockout in periapical bone resorption and Treg cell stability, and the underlying mechanism was explored through in vitro experiments. In vivo Treg cell adoptive transfer was performed to investigate the effects of Treg cells on the progression of apical periodontitis.ResultsOur findings find that the hyperactivated Nlrp3 inflammasome is present in human periapical lesions and plays a vital role in the immune‐related periapical bone loss. Using a mouse model of apical periodontitis, we observe that Nlrp3 deficiency is resistant to bone resorption. This protection was accompanied by elevated generation and infiltration of local Treg cells that displayed a notable ability to suppress RANKL‐dependent osteoclast differentiation. In terms of the mechanism of action, Nlrp3 deficiency directly inhibits the osteoclast differentiation and bone loss through JNK/MAPK and NF‐κB pathways. In addition, Nlrp3 induces pyroptosis in the stem cells from apical papilla (SCAPs), and the subsequent release of cytokines affects the stability of Treg cell in periapical lesions, leading indirectly to enhanced bone resorption. In turn, adoptive transfer of both Nlrp3‐deficient and wild‐type Treg cells effectively prevent the bone erosion during apical periodontitis.ConclusionsTogether, our data identify that the Nlrp3 inflammasome modulates the Treg cell stability and osteoclastogenesis in the periapical inflammatory microenvironment, thus determining the progression of bone erosion.
Humanizing Metaverse: Psychological involvement and masstige value in retail versus tourism platforms
Authors: Jin Dan 
Published: March 2024

AbstractAcross two experimental studies, this research puts forward the concept of avatars' self‐representation and regulatory message framing to discover psychological involvement and masstige value in retail and tourism platforms, demonstrating how avatar self‐representation and message framing can potentially indicate Metaverse psychological involvement in the Metaverse. The proteus effect was applied to study avatar falsity. The promotion/prevention regulatory focus theory was employed to examine the effect of message framing in hypothetical retail and tourism platforms in Study 1 (n = 846). Further determinants of masstige value were captured using the masstige theory. In parallel with Study 1, Study 2 (n = 817) adopted real‐world examples of the Metaverse—Gucci Vault Plaza (Retail) and Baidu Xi Rang (Tourism) to equally examine the effect of users' psychological involvement on Metaverse involvement via masstige value. Respondents were allocated to either a self‐promotion or self‐verification avatar condition. The results demonstrated significant downstream effects of these specific self‐promotion and self‐verification categories, thereby contributing to an important conceptual subdimension in the measurement and understanding of online self‐perception within the context of avatars. When participants imagined using a self‐verification avatar in the prevention‐focused message condition, significant effects were observed. Further, a Metaverse platform is a critical factor that affects masstige. Exploring the masstige value at the Metaverse demonstrates the relationship between self‐enhancement and masstige desire for luxury that underscores Metaverse involvement. The research presented a critical insight into the carryover effects of self‐representation of avatars that can establish a new form of meta‐interaction. This research provides insights into technology in virtual retail and tourism Metaverse applications to provide users with more psychologically authentic solutions within the Metaverse.
Editor's Highlights – April 2024
Authors: Kemény Lajos 
Published: March 2024

SummaryIn the April issue of the Journal, we highlight the topical application of honey and garlic, detailing their active ingredients and elucidating the mechanisms by which these natural agents work. Additionally, this issue will spotlight the disparities in laboratory monitoring among patients undergoing isotretinoin treatment and provide significant data regarding the nonassociation between isotretinoin use and impulsivity in individuals with acne.
Careers in “woman‐friendly” occupations: Investigating the role of beauty consultant in the era of neoliberalism
Authors: Nagayama Riho , Sato Fumika 
Published: March 2024

AbstractThis article explores the paradoxical nature of beauty consultant careers in Japan. Despite being considered a “woman‐friendly” occupation, it reveals the challenging aspects of this profession in a neoliberal context. Japan's gender gap in employment is stark, with women often engaged in precarious positions, earning significantly less than men. The beauty industry, perceived as advancing women's empowerment, presents opportunities for women in management roles. However, the profession of a beauty consultant demands continuous beauty upkeep, making it a potentially unsustainable career. The research draws on interviews with former and current beauty consultants, supplemented by statistical data and observational research. It highlights their working environment, including entry requirements, training, career advancement, and aesthetic labor demands such as wearing company uniforms, using specific makeup, and maintaining a youthful appearance. Despite a seemingly supportive environment with maternity leave and career advancement prospects, the research reveals the reality of aesthetic labor demands, limited career progression, and challenges faced by women in sustaining their careers after life events like childbirth. Neoliberal norms impact these women, emphasizing self‐fulfillment, maintaining youth and beauty, and working post life events. In conclusion, the research offers insights into the gendered labor dynamics in Japan and broadens understanding of women's labor in the neoliberal context. It calls for a deeper examination of “woman‐friendly” workplaces and underscores the need to recognize the challenges women face in career progression in such environments.
Analysis of factors associated with needlestick injuries of clinical nurses by applying a human factor analysis and classification system: A nationwide cross‐sectional survey
Authors: Gao Huimin , Liu Mengyuan , Su Yanan , Li Yinglan , Tian Lingyun 
Published: March 2024

AbstractAimsThis study aims to investigate the current situation of needlestick injuries (NSIs) of clinical nurses and identify associated factors by using the theoretical framework of the human factors analysis and classification system (HFACS).DesignA nationwide cross‐sectional survey was conducted.MethodsMulti‐stage sampling was used to investigate 3336 nurses in 14 Chinese hospitals. Descriptive statistics and univariate and multivariate logistic regression were employed to reveal the rate of NSIs and their associated factors.ResultsA total of 970 nurses (29.1%) reported having experienced at least one NSI in the past year. The multivariate logistic regression analysis showed that good hospital safety climate and clinical nurses in intensive care unit (ICU) and emergency department had protective effects against NSIs compared with nurses in internal medicine department. The nurse, senior nurse, and nurse in charge have significantly increased the risk for NSIs compared with the associate chief nurse or above. Patients with poor vision but wearing glasses and poor vision but not wearing glasses were more prone to have NSIs. Working in the operating room compared with internal medicine, average weekly working time of >45 h compared with ≤40 h and poor general health led to increased risk of NSIs.ConclusionThe rate of NSIs in clinical nurses was high in China. Individual factors including professional title, department, visual acuity and general mental health and organisational factors including weekly working hours and hospital safety atmosphere were significantly correlated with the occurrence of NSIs.Relevance to Clinical PracticeNursing managers should focused on physical and psychological conditions of clinical nurses, and organisational support is required to enhance the hospital safety atmosphere.No Patient or Public ContributionContributions from patients or the public are irrelevant because this study aims to explore current situation and factors associated with NSIs in clinical nurses.
Efficacy of auricular acupressure on lung function among chronic obstructive pulmonary disease: A meta‐analysis of randomised controlled trials
Authors: Wang Bingjie , Liang Qi , Chen Yu , Liu Yang , Zhang Chunmei 
Published: March 2024

AbstractObjectivesTo systematically evaluate the efficacy of auricular acupressure on lung function, sleep quality and quality of life in chronic obstructive pulmonary disease patients.BackgroundAuricular acupressure has been increasingly used in chronic obstructive pulmonary disease patients, such as lung function and sleep quality, but the efficacy has not yet been unified.DesignA meta‐analysis of randomised controlled trials.MethodsRandomised controlled trials comparing auricular acupressure intervention with non‐auricular acupressure intervention in chronic obstructive pulmonary disease patients were included. We searched English databases and Chinese databases from the inception to 26 December 2022. The risk of bias was assessed by the Cochrane risk of bias tool. The PRISMA statement was used to report a meta‐analysis.ResultsA total of 12 randomised controlled trials with 987 chronic obstructive pulmonary disease patients were included. The meta‐analysis showed that auricular acupressure had significant differences in improving lung function, including FEV1 (MD = 0.29, 95% CI: 0.21 to 0.37, p < .0001), FVC (MD = 0.24, 95% CI: 0.14 to 0.34, p < .0001) and FEV1/FVC (MD = 4.70, 95% CI: 3.63 to 5.78, p < .0001). There was also a positive effect on sleep quality (MD = −0.71, 95% CI: −0.89 to −0.53, p < .0001) and quality of life (MD = −3.20, 95% CI: −3.92 to −2.49, p < .0001).ConclusionsThe results indicated auricular acupressure had a positive efficacy in chronic obstructive pulmonary disease patients to improve lung function, sleep quality and quality of life, but these results should be treated with caution due to the low quality of included studies. Future researchers need to conduct more high‐quality randomised controlled trials to provide a solid basis to demonstrate the efficacy of auricular acupressure in chronic obstructive pulmonary disease patients.Relevant to Clinical PracticeAuricular acupressure has the advantages of being non‐invasive, convenient and without significant side effects. This review suggested auricular acupressure could be considered a non‐pharmacological intervention for patients. Clinical nurses can teach chronic obstructive pulmonary disease patients to perform auricular acupressure to help self‐manage complications.Patient or Public ContributionNo Patient or Public Contribution.
‘Executive robbery’: UK public law, race, and ‘regimes of dispossession’ in the Chagos Archipelago
Authors: CHOWDHURY TANZIL 
Published: March 2024

AbstractThis article explores the relationship between United Kingdom (UK) public law and ‘regimes of dispossession’, taking the Chagos Archipelago as its point of departure. This article argues that this instance of dispossession, typically understood as fortifying the military power of the United States, was also part of a wider geography of states dispossessing land for a specific set of economic purposes that were tied to particular class interests. Deploying a relational geographies of materialist public law approach, the article reconceptualizes the scales of public law, extending an examination of its effects and constitution beyond the territory of the UK, and considers public law's relation to capitalism, exploring the ways in which its technologies (re)produce regimes of dispossession. The article argues that the dispossession of the Chagos Archipelago was an example of ‘executive robbery’, a racialized dispossession (produced through conferring displaceability and disposability on the Chagossians) enacted to construct military infrastructure that was key for accumulation in the Middle East.
Seedling recruitment in response to stand composition, interannual climate variability, and soil disturbance in the boreal mixed woods of Canada
Authors: Maleki Kobra , Marchand Philippe , Charron Danielle , Bergeron Yves 
Published: March 2024

AbstractAimSeedling recruitment is a vital process for forest regeneration and is influenced by various factors such as stand composition, climate, and soil disturbance. We conducted a long‐term field experiment (18 years) to study the effects of these factors and their interactions on seedling recruitment.LocationOur study focused on five main species in boreal mixed woods of eastern Canada: trembling aspen (Populus tremuloides), paper birch (Betula papyrifera), white spruce (Picea glauca), balsam fir (Abies balsamea), and white cedar (Thuja occidentalis).MethodsSixteen 1‐m2 seedling monitoring subplots were set up in each of seven stands originating from different wildfires (fire years ranging from 1760 to 1944), with a soil scarification treatment applied to every other subplot. Annual new seedling counts were related to growing‐season climate (mean temperature, growing degree days and drought code), scarification, and stand effects via a Bayesian generalized linear mixed model.ResultsSoil scarification had a large positive effect on seedling recruitment for three species (aspen, birch and spruce). As expected, high mean temperatures during the seed production period (two years prior to seedling emergence) increased seedling recruitment for all species but aspen. Contrary to other studies, we did not find a positive effect of dry conditions during the seed production period. Furthermore, high values of growing degree days suppressed conifer seedling recruitment. Except for white cedar, basal area was weakly correlated with seedling abundance, suggesting a small number of reproductive individuals is sufficient to saturate seedling recruitment.ConclusionOur findings underscore the importance of considering multiple factors, such as soil disturbance, climate, and stand composition, as well as their effects on different life stages when developing effective forest management strategies to promote regeneration in boreal mixed‐wood ecosystems.