bluuebunny/crossref_metadata_2025_split huggingface dataset:
The use and application of intensive care unit diaries: An instrumental multiple case study
Authors: Johansson Maria , Wåhlin Ingrid , Magnusson Lennart , Hanson Elizabeth 
Published: February 2024

Aims and objectives
The study aim was to explore the use of an Intensive Care Unit (ICU) diary within four different ICUs units in Sweden and thereby contribute to practice guidelines regarding the structure, content and use of an ICU diary.

Background
ICU diaries are used to aid psychological recovery among critical care patients, but differences remain in diary writing both within and across countries. Few studies have focused on the combined views and experiences of ICU patients, family members and nursing staff about the use of ICU diaries.

Design
An instrumental multiple case study design was employed.

Methods
Three focus groups interviews were carried out with 8 former patients and their family members (n = 5) from the research settings. Individual interviews were carried out with 2 patients, a family member and a nurse respectively. Observations, field notes, documentary analysis and conversations with nursing staff were also conducted. Consolidated criteria for reporting qualitative research (COREQ) was followed.

Results
The qualitative findings firstly consisted of a matrix and descriptive text of the four ICU contexts and current practices. This highlighted that there were similarities regarding the aims and objectives of the diaries. However, differences existed across the case study sites about how the ICU diary was developed and implemented. Namely, the use of photographs and when to commence a diary. Second, a thematic analysis of the qualitative data regarding patients’ and family members’ use of the ICU diary, resulted in four themes: i) the diary was used to take in and fully understand the situation; ii) the diary was an opportunity to assimilate warm, personalised and human care; iii) the diary was used to manage existential issues; and iv) the diary was a tool in daily activities.

Conclusions
Analysis of the instrumental case study data led to the identification of core areas for inclusion in ICU diary practice guidelines.
Risk factor control and cardiovascular events in patients with type 2 diabetes mellitus
Authors: Song Do Kyeong , Hong Young Sun , Sung Yeon-Ah , Lee Hyejin 
Published: February 2024

Background
Since patients with type 2 diabetes mellitus (T2DM) have an increased risk of cardiovascular events, interventions addressing risk factors reduce the incidence of cardiovascular disease (CVD) events. This study aimed to evaluate the difference in the incidence of CVD events according to risk factor control in patients with diabetes with and without cardio-renal disease.

Methods
We analyzed 113,909 patients with diabetes and 290,339 without diabetes using data released by the National Health Insurance Service (NHIS).

Results
Among patients with diabetes with four or five poorly controlled risk factors, hazard ratio for CVD events was 1.19 (95% confidence interval [CI], 1.06–1.34) in patients with cardio-renal disease and 2.31 (95% CI, 1.95–2.74) in patients without cardio-renal disease compared to patients with diabetes without risk factors. In subjects with diabetes and cardio-renal disease, patients with four or five poorly controlled risk factors had a higher risk of CVD mortality compared to subjects without risk factors (hazard ratio, 1.64; 95% CI, 1.18–2.30).

Conclusion
Controlling cardiovascular risk factors reduced the incidence of CVD events in patients with diabetes, especially those without cardio-renal disease. The degree of risk control was strongly associated with CVD mortality in patients with diabetes with baseline cardio-renal disease.
Spanish version of the short European Health Literacy Survey Questionnaire HLS-Q12: Transcultural adaptation and psychometric properties
Authors: Muñoz-Villaverde Sergio , Serrano-Oviedo Leticia , Martínez-García María , Pardo Yolanda , Tares-Montserrat Llüisa , Gómez-Romero Francisco Javier , Garcimartin Paloma 
Published: February 2024

Background
Health literacy has a direct impact on the health of populations. It is related to education, capacity for self-care, and management of health resources. The Health Literacy Survey Questionnaire HLS-Q12 is one of the reference instruments but has not yet been adapted to Spanish. The aims of the study were to cross-culturally adapt and evaluate the psychometric properties of the Spanish version of the HLS-Q12.

Methods
Data was collected from June 2020 to March 2022. The sample consisted of 60 patients who initiated cancer treatment for the first time within a clinical trial. Double direct translation, back-translation, cognitive debriefing with a 10-patient sample, and an expert committee were used for cross-cultural adaptation. For validation of the HLS-Q12, a psychometric analysis was performed to assess feasibility, reliability, sensitivity to change and construct validity with other measures such as health-related quality of life, empowerment, and health needs.

Results
The HLS-Q12 is equivalent at the semantic, conceptual, and content level to the original version and its psychometric properties demonstrated good internal consistency with a Cronbach’s alpha of 0.88 and a McDonald´s omega of 0.91, a high degree of fit for the confirmatory factor analysis, and a statistically significant sensitivity to change (p = 0.025).

Conclusions
Based on robust psychometric values, the Spanish version of HLS-Q12 was found to be a good cross-culturally adapted tool for collecting correct information on health literacy in cancer patients regardless of tumour type or stage. Although more studies are needed, this version of HLS-Q12 could be used in research for collecting data on the health literacy needs of Spanish-speaking patients.
Vitamin D levels of pregnant immigrant women and developmental disorders of language, learning and coordination in offspring
Authors: Arrhenius Bianca , Surcel Heljä-Marja , Hinkka Yli-Salomäki Susanna , Brown Alan , Cheslack-Postava Keely , Sourander Andre 
Published: February 2024

Background
Prenatal vitamin D deficiency is a common health concern among immigrants. No previous studies have examined the associations between prenatal vitamin D levels and developmental disorders of language, scholastic skills, and coordination in an immigrant sample.

Methods
The sample included 542 immigrant mothers of cases with language, scholastic, coordination or mixed developmental disorders, 443 immigrant mothers of controls without these disorders and 542 Finnish mothers of controls. Maternal vitamin D was measured in serum samples collected during early pregnancy and stored in a national biobank.

Results
The mean vitamin D levels during pregnancy were 25.0 (SD 14.4) nmol/L for immigrant mothers of cases, 25.4 (SD 15.5) for immigrant mothers of controls and 42.3 (SD 19.1) for Finnish mothers of controls. Low maternal vitamin D levels during pregnancy were not associated with the selected developmental disorders in offspring when immigrant mothers of cases were compared to immigrant mothers of controls (adjusted OR for continuous log-transformed vitamin D: 1.01, 95% CI 0.75–1.36, p = 0.96). When immigrant mothers of cases were compared to Finnish mothers of controls, the adjusted OR for continuous vitamin D was 18.94 (95% CI 11.47–31.25), p <0.001). The results were similar when vitamin D was examined as a categorical variable or divided into quintiles.

Conclusions
Prenatal vitamin D levels were low, and similar, among immigrant mothers of cases with selected developmental disorders and unaffected controls. This indicates that vitamin D unlikely mediates previously observed associations between maternal immigrant status and the selected developmental disorders in offspring. The proportion of immigrant mothers with severe vitamin D deficiency was very high, which underlines the importance of prenatal counselling and overall public health efforts to improve immigrant health.
Effects of team-based mixed reality simulation program in emergency situations
Authors: Choi Moon-Ji , Kim Kyeng-Jin 
Published: February 2024

Background
This study aimed to demonstrate the effectiveness of a team-based mixed reality simulation program about emergencies.

Method
A nonequivalent control group pretest-posttest design was utilized. We recruited 32 nurses for the experimental group and 32 for the control group, resulting in a total of 61 nurses ultimately included as subjects for analysis. This mixed reality program is designed to facilitate responses in cardiopulmonary resuscitation situations simultaneously using four HoloLens. With shared content visible to all four trainees, the participants could engage in simulation while freely communicating. The experimental group engaged in cardiopulmonary resuscitation emergency simulation while wearing the HoloLens, while the control group was provided with written CPR materials.

Results
There were significant increases in the experimental group’s critical thinking (p < .001), learning transfer motivation (p = .006), communication confidence (p = .033), and learning immersion (p < .001) compared to the control group.

Conclusion
The program developed in this study presents an effective educational strategy that can enhance nurses’ emergency competencies and leverage the practicality of mixed reality.
Machine learning methods in differential diagnosis of ACTH-dependent hypercortisolism
Authors: Golounina O. O. , Belaya Zh. E. , Voronov K. A. , Solodovnikov A. G. , Rozhinskaya L. Ya. , Melnichenko G. A. , Mokrysheva N. G. , Dedov I. I. 
Published: February 2024

AIM: To develop a noninvasive method of differential diagnosis of ACTH-dependent hypercortisolism, as well as to evaluate the effectiveness of an optimal algorithm for predicting the probability of ectopic ACTH syndrome (EAS) obtained using machine learning methods based on the analysis of clinical data.MATERIALS AND METHODS: As part of a single-center, one-stage, cohort study, a retrospective prediction of the probability of EAS among patients with ACTH-dependent hypercortisolism was carried out. Patients were randomly stratified into 2 samples: training (80%) and test (20%). Eleven machine learning algorithms were used to develop predictive models: Linear Discriminant Analysis, Logistic Regression, elastic network (GLMNET), Support Vector machine (SVM Radial), k-nearest neighbors (kNN), Naive Bayes, binary decision tree (CART), C5.0 decision tree algorithms, Bagged CART, Random Forest, Gradient Boosting (Stochastic Gradient Boosting, GBM).RESULTS: The study included 223 patients (163 women, 60 men) with ACTH-dependent hypercortisolism, of which 175 patients with Cushing’s disease (CD), 48 — with EAS. As a result of preliminary data processing and selection of the most informative signs, the final variables for the classification and prediction of EAS were selected: ACTH level at 08:00 hours, potassium level (the minimum value of potassium in the active stage of the disease), 24-h urinary free cortisol, late-night serum cortisol, late-night salivary cortisol, the largest size of pituitary adenoma according to MRI of the brain. The best predictive ability in a training sample of all trained machine learning models for all three final metrics (ROC-AUC (0.867), sensitivity (90%), specificity (56.4%)) demonstrated a model of gradient boosting (Generalized Boosted Modeling, GBM). In the test sample, the AUC, sensitivity and specificity of the model in predicting EAS were 0.920; 77.8% and 97.1%, respectively.CONCLUSION: The prognostic model based on machine learning methods makes it possible to differentiate patients with EAS and CD based on basic clinical results and can be used as a primary screening of patients with ACTH-dependent hypercortisolism.
Nie na miejscu. Strategie dysocjacyjne w poezji Karin Boye i Marii Pawlikowskiej-Jasnorzewskiej
Authors: Skoczyńska Maria 
Published: February 2024

Artykuł poświęcony jest zagadnieniu rozdarcia istniejącego w twórczości Karin Boye i Marii Pawlikowskiej-Jasnorzewskiej oraz wykorzystaniu przez nie terapeutycznej funkcji natury. Bohaterki liryczne tych poetek tęsknią za bezpiecznym miejscem, którego nie mogą we współczesnym świecie znaleźć. Wykorzystują więc strategię radzenia sobie z wewnętrznym rozdarciem, tj. „dysocjację literacką”. Analiza porównawcza twórczości Boye i Pawlikowskiej-Jasnorzewskiej ma przybliżyć ich podejście do dysocjacji, a także sposób jej wykorzystywania w konkretnych tekstach poetyckich.
Erstellung und Integration von Verwaltungsschalen aus Heterogenen Datenquellen
Authors: Zhao Jingyun , Vogel-Heuser Birgit , Hartl Fandi , Höfgen Josua , Ocker Felix , Vojanec Bernd , Markert Timo , Kraft André 
Published: February 2024

Zusammenfassung
Heterogene Datenquellen und inkonsistente Schnittstellen zwischen verschiedenen Ingenieursdisziplinen stellen eine enorme Herausforderung bei der Erstellung einer virtuellen Repräsentation eines realen Produkts, Anlage oder Prozesses dar. Zu dieser digitalen Darstellung wird die Verwaltungsschale (VWS) als ein standardisiertes Konzept vorgeschlagen. Jedoch erfordert die VWS-Erstellung oft erheblichen manuellen Aufwand, um Informationen aus technischen Engineering- und Betriebsdaten zu extrahieren und zu strukturieren. Der folgende Beitrag schlägt einen semi-automatisierten Ansatz zur Extraktion von Engineering-Informationen aus Dokumenten der Formate PDF, STP, XML, AML sowie URDF vor, um anhand dieser Informationen mehrere VWS zu erstellen, die zusammengeführt werden können. Anhand dreier Anwendungsfälle werden die Möglichkeiten und Grenzen des Ansatzes diskutiert.
Hate speech mainstreaming in the Greek virtual public sphere: A quantitative and qualitative approach
Authors: Tsirbas Yannis , Zirganou-Kazolea Lina 
Published: February 2024

Abstract
This study delves into the manifestation and characteristics of hate speech in the Greek online public sphere, specifically exploring its most prominent forms, namely racism, anti-immigrant sentiment, nationalism, sexism, and homophobia/transphobia. Combining quantitative and qualitative methods, the research analyzes popular Greek online news media. It aims to uncover the visibility and operational patterns of hate speech, addressing key questions about its prevalence and presentation on these platforms. Findings reveal the normalization of discriminatory speech, particularly sexism and nationalism, in the digital landscape. Moreover, distinct themes and linguistic elements associated with different forms of hate speech highlight the intertwined nature of these discriminatory expressions. This research sheds light on the pervasive nature of hate speech in Greece’s online realm, emphasizing its implications for democratic principles.
KCTD5 regulates Ikaros degradation induced by chemotherapeutic drug etoposide in hematological cells
Authors: Ma Lan , Yin Changqing , Zhang Yi , Li Jie , Shi Liuzhi , Zhou Tong , Huang Xixi , Liu Yaqi , Cao Jiawei , Wu Guang , Gu Haihua , He Licai 
Published: February 2024

Abstract
Therapy-related leukemia carries a poor prognosis, and leukemia after chemotherapy is a growing risk in clinic, whose mechanism is still not well understood. Ikaros transcription factor is an important regulator in hematopoietic cells development and differentiation. In the absence of Ikaros, lymphoid cell differentiation is blocked at an extremely early stage, and myeloid cell differentiation is also significantly affected. In this work, we showed that chemotherapeutic drug etoposide reduced the protein levels of several isoforms of Ikaros including IK1, IK2 and IK4, but not IK6 or IK7, by accelerating protein degradation, in leukemic cells. To investigate the molecular mechanism of Ikaros degradation induced by etoposide, immunoprecipitation coupled with LC-MS/MS analysis was conducted to identify changes in protein interaction with Ikaros before and after etoposide treatment, which uncovered KCTD5 protein. Our further study demonstrates that KCTD5 is the key stabilizing factor of Ikaros and chemotherapeutic drug etoposide induces Ikaros protein degradation through decreasing the interaction of Ikaros with KCTD5. These results suggest that etoposide may induce leukemic transformation by downregulating Ikaros via KCTD5, and our work may provide insights to attenuate the negative impact of chemotherapy on hematopoiesis.
Preliminary results of scintillation monitoring at KLEF-Guntur low latitude station using GNSS software defined radio
Authors: Gandreti Venkata Ramana , Miriyala Sridhar , Tanneeru Venkateswara Rao , Devanaboyina Venkata Ratnam , Deshpande Kshitija 
Published: February 2024

Abstract
Global Navigation Satellite Systems (GNSS) have become an integral part of modern life, supporting various applications, from precise positioning and navigation to timing and synchronization. However, GNSS signals are vulnerable to natural interferences including various atmospheric disturbances, with ionospheric scintillations being a significant challenge. Ionospheric scintillations, caused by irregularities in the Earth’s ionosphere, introduce rapid fluctuations in the amplitude and phase of GNSS signals. These fluctuations can severely degrade the accuracy and reliability of GNSS receivers, leading to positioning errors and navigation failures. Hence, it is crucial to develop effective mitigation strategies. One of the promising approaches to mitigate ionospheric scintillations is the utilization of Software Defined Radio (SDR) technology in GNSS receivers. SDR allows for real-time adaptation to changing signal conditions, enabling the receiver to detect scintillations and adjust its signal processing accordingly. This adaptability enhances the receiver’s stability against ionospheric disturbances, ensuring more robust and accurate positioning and navigation. In this paper, preliminary results of GNSS SDR (Make: iP-Solutions, Japan) installed at Koneru Lakshmaiah Education Foundation (KLEF), Vaddeswaram (Guntur) (16.44° N, 80.62° E) are presented. Amplitude scintillation index (S4) variations for different PRNs and subsequent positioning results are interpreted from April to September 2023. The results are compared and validated with those of the co-located Novatel GNSS receiver and NAVIC receiver. Most of the S4 variations correlate well with the S4 values from the Novatel and NAVIC receivers. S4 observations from the Septentrio receiver at Daytona Beach (Florida) are also presented. The results of SDR will be extended further for the development of scintillation mitigation algorithms. We plan to install an SDR and employ similar mitigation strategy at this location in the near future.
Psychische und psychosomatische Folgen von Alltagsrassismus und Antisemitismus, Trauma und Internalisierung
Authors: Velho Astride 
Published: February 2024

Zusammenfassung
Erfahrungen von Rassismus und Antisemitismus haben Auswirkungen auf die Gesundheit, und obwohl diese Tatsache im deutschsprachigem Raum kaum Beachtung findet, ist sie hoch bedeutsam für die Forschung und Praxis von Public Health. Der Beitrag gibt einen kurzen Überblick über internationale Forschungsergebnisse zu den psychischen und psychosomatischen Effekten von Rassismus und Antisemitismus. Dabei wird die traumatisierende Wirkung von alltäglichen, multiplen Diskriminierungserfahrungen und Mikroaggressionen ebenso ausgeführt, wie die psychodynamischen Folgen, die durch Internalisierungen entstehen können.
Vielfalt und Gesundheit in Betrieb und Organisation
Authors: Faller Gudrun 
Published: February 2024

Zusammenfassung
Ziel des vorliegenden Beitrags ist es, auf die Public Health-Relevanz des Diversityansatzes im Kontext der Erwerbsarbeit aufmerksam zu machen. Zu diesem Zweck wird einleitend auf aktuelle Herausforderungen der Arbeitswelt eingegangen und davon ausgehend auf die strukturelle Benachteiligungen spezifischer Gruppen in der Arbeitswelt hingewiesen. Vor diesem Hintergrund werden die Begriffe Diskriminierung und Vielfalt im betrieblichen Kontext diskutiert, um im Fazit eine Erweiterung bislang vorliegender Konzepte zur gesundheitsfördernden Organisationsentwicklung im Sinne des Diversityansatzes zu empfehlen.
Solidarversicherung als Kulturversicherung
Authors: Bröckerhoff Peter 
Published: February 2024

Zusammenfassung
Sozialversicherungen entlasten Individuen durch Absicherung elementarer Lebensrisiken, stiften soziale Integration, wirken demokratisierend und stellen zugleich eine rechtsförmige Rückversicherung dieser kulturellen Errungenschaften dar. Allerdings bedarf es einer genauen Reflexion des kulturellen Erbes der Sozialversicherung, damit diese sich nicht in Widersprüche mit ihrem solidarischen Anspruch verstrickt, der darin besteht, Zugang für alle Mitglieder einer politischen Gemeinschaft zu bieten.
Medizinische Versorgung von Menschen mit Beeinträchtigung: Herausforderungen und Bedarfe
Authors: Ottersbach Kristina , Kühnel Larissa , Wattenberg-Karapinar Ivonne , Hornberg Claudia , Lätzsch Rebecca 
Published: February 2024

Zusammenfassung
Der Beitrag behandelt die gesundheitliche Versorgung von Menschen mit Beeinträchtigung in Deutschland, insbesondere im stationären Setting. Thematisiert werden Erfahrungen, Herausforderungen und Bedarfe aus Expert*inneninterviews mit Ärzt*innen und Personen aus dem sprachtherapeutischen und sonderpädagogischen Bereich. Die Ergebnisse zeigen, dass u. a. strukturelle Veränderungen, mehr Zeit für die Behandlung und Schulungen erforderlich sind, um eine bedarfsorientierte Versorgung zu schaffen.
Starter Steps as to the Importance of Keeping an Accurate Training Log
Authors: Kraemer William J. , Nitka Mike 
Published: February 2024

ABSTRACT
Despite advances in strength and conditioning science, a gap exists in the optimal utilization of training logs for athlete monitoring. Accurate logs serve as a critical interface for player development, offering real-time evaluation and enabling long-term data analysis. This article addresses the reluctance among professionals to transition from traditional paper-based methods to digital platforms, citing this as a hindrance to correlating workout data with performance metrics. It emphasizes the individualized nature of training adaptation and the necessity of advanced technologies and software skills for effective program evaluation. The article also details critical variables to be captured in workout logs, both quantitative and qualitative, and underscores their role in decision-making, workout efficacy, and athlete safety. By embracing digital advancements, professionals can elevate the quality of strength and conditioning programs, ensuring they are executed as designed and achieve desired outcomes.
Dispersion and Spatial Distribution of Air Voids or Microspheres in Assessing Frost Resistance of Concrete
Authors: Attiogbe Emmanuel K. 
Published: February 2024

Abstract
The standard spacing factor developed by Powers is typically used to evaluate the quality of the air void system in hardened concrete, but it does not always correlate with durability of the concrete. Several air void spacing equations, which are also applicable when polymeric microspheres are used in place of air entrainment, have been proposed because of the need for a more robust and comprehensive basis to evaluate the quality of the air void system. However, the spacing parameters provided by the various proposed equations, when used as sole measures in predicting the frost resistance of concrete, do not seem to do any better than the standard spacing factor. Dispersion and spatial distribution have been shown to be effective ways of describing air void or microsphere systems in hardened concrete because they have been quantified to establish criteria to assess the frost resistance of concrete. In this paper, dispersion and distribution factors are further elaborated upon to explain how they characterize zones that are protected by air voids or microspheres in the concrete. Criteria to assess the durability of concrete under rapid cycles of freezing and thawing based on the dispersion and distribution factors are linked to the exposure classes defined in the ACI 318 Code and in the recently proposed Unified Durability Guidance in ACI Committee Documents.