bluuebunny/crossref_metadata_2025_split huggingface dataset:
Weapons of mass division: Sputnik Latvia's Russophobia narratives and testing the rejection‐identification model in Russian speakers in Latvia
Authors: Hoyle Aiden , Powell Tom , Doosje Bertjan , van den Berg Helma , Wagnsson Charlotte 
Published: March 2024

AbstractThe effects of exposure to Russian propaganda have long been feared; however, academic research examining responses is scarce. This study aims to investigate the responses of Russian speakers in Latvia to a narrative propagated by the Kremlin‐sponsored media outlet Sputnik Latvia that narrates Latvian government policy as Russophobic. The potential to entrench existing ethnopolitical divisions has been highlighted as a possible effect of Russian speakers consuming this narration. We adopt a comprehensive, mixed‐method research approach, where we first provide an analysis of the content of Sputnik Latvia's Russophobia narrative in its recent output. Then, using this analysis, we examine how Russian‐speaking participants respond to this content in a preregistered survey experiment and a focus group. Theoretically, we orient around the rejection‐identification model. This predicts individuals to generally experience lower well‐being after perceiving group‐based discrimination, but that embracing the stigmatized identity can help maintain well‐being despite this perceived devaluation. Our results showed that even brief exposure to Sputnik Latvia's Russophobia narrative led to higher levels of perceived discrimination and group identification in Russian speakers. However, we found no significant effects on well‐being, which deviates from extant literature on discrimination. We discuss the reasons for this and suggest future directions.
Epididymitis with Pasteurella multocida isolated from two male Japanese Black beef calves
Authors: Kanno Chihiro , Sato Shogo , Maeda Yosuke , Ando Ryo , Park Chun‐Ho , Kawaguchi Hiroaki , Tanabe Taishi , Takahashi Fumiaki 
Published: March 2024

AbstractTwo male Japanese Black calves developed an enlarged scrotum and testis. Orchiectomy was performed and pus was collected during surgery. After removal of the testis, bacteriological and histopathological examinations were conducted to investigate the cause and confirm the diagnosis. Based on the results obtained, both cases were diagnosed with epididymitis caused by an infection with Pasteurella multocida. This is the first study to show that P. multocida causes epididymitis in male calves. Further studies are required to clarify the details underlying the infection of calves with P. multocida.
The effect of cross‐border shopping on commodity tax revenue: results from Norway's COVID‐19 border closings
Authors: Friberg Richard , Halseth Emil M. S. , Steen Frode , Ulsaker Simen A. 
Published: March 2024

AbstractWe use grocery data from Norway and COVID‐19 border closings to gauge the effect of cross‐border shopping on commodity tax revenue. Detailed store–category‐level data identify differential treatment effects that depend on distance to Swedish stores. Economically significant effects extend to up to two hours' drive from the border, and even further for prominent cross‐border shopping products, such as beer, cigarettes, and carbonated soft drinks. Across all products, cross‐border shopping decreases tax revenue from VAT by 3.6 percent at the national level. National commodity tax revenue from carbonated soft drinks (subject to a sugar tax) is reduced by 8.1 percent and from cigarettes by 11.9 percent.
A phylogenetic framework of Palaearctic and Indomalayan Limacodidae (Lepidoptera, Zygaenoidea) based on sequence capture data
Authors: Liang Jiamin , Zhu Yaowei , Solovyev Alexey V. , He Mao , Lohman David J. , Wahlberg Niklas , Li Wentao , Li Jing , Wang Min , Liang Dan , Wang Houshuai 
Published: March 2024

AbstractThe slug moth family Limacodidae is a cosmopolitan group of economic importance, but its higher level systematics remains poorly understood. Here, we present a robust, higher level phylogenetic framework for Palaearctic and Indomalayan members of the family using sequence capture data of 148 nuclear protein‐coding and 13 mitochondrial markers from 145 samples of 126 species in 67 genera representing all five morphologically delineated limacodid lineages. Our results strongly support the monophyly of Limacodidae in which six major clades are recognized. The relationships among these clades are revealed, with Phrixolepia‐clade being the most basal group followed by Apoda‐clade, Euphlyctinides‐clade, Cania‐clade and Phlossa‐clade + Parasa‐clade, respectively. We also add publicly available DNA barcode sequences from additional species worldwide to this phylogenetic framework to infer the most completely sampled phylogeny of Limacodidae to date. Our work provides a major step towards understanding the systematics and evolution of slug moths.
A placebo‐controlled, double‐blind study evaluating the effect of orally administered polyunsaturated fatty acids on the oclacitinib dose for atopic dogs
Authors: Schäfer Laura , Thom Nina 
Published: March 2024

AbstractBackgroundSupplementation of polyunsaturated fatty acids (PUFA) enables dose reduction of prednisolone and ciclosporin in canine atopic dermatitis (cAD).ObjectiveTo determine if oral administration of PUFA reduces the dose of oclacitinib in cAD.AnimalsTwenty‐two client‐owned dogs with cAD receiving oclacitinib.Materials and MethodsDogs received a fish oil product (PUFA) or paraffin oil (placebo) for 16 weeks. Owners adjusted the oclacitinib dose according to daily pruritus assessments. On Day (D)0, D56 and D112, Canine Atopic Dermatitis Extent and Severity Index, fourth iteration (CADESI‐04), pruritus Visual Analog Scale (PVAS), quality‐of‐life score (QoL), Global Assessment (GA), quality‐of‐coat (QoC) and adverse events were recorded.ResultsMean daily oclacitinib dose was significantly reduced in the PUFA group from 0.51 ± 0.20 mg/kg/24 h (D0) to 0.19 ± 0.14 mg/kg/24 h (D85–112; p < 0.00001) and not in the placebo group (D0: 0.70 ± 0.33 mg/kg/24 h; D85–112: 0.53 ± 0.35 mg/kg/24 h, p = 0.5422). CADESI‐04 did not change over time or differ between groups. PVAS was significantly lower in the PUFA group (2.8 ± 1.5) compared to placebo (4.2 ± 1.6) at D112 (p = 0.0375). QoL and QoC improved only in the PUFA group (QoL: D0: 20 ± 7, D112: 12 ± 5, p = 0.0057; QoC: D0: 0 ± 0.5, D112: 1 ± 0.5, p = 0.0410). GA on D112 was higher in the PUFA group (p = 0.008). No adverse events were observed.ConclusionOral supplementation of PUFA allowed dose reduction of oclacitinib and improved PVAS, QoL, QoC and GA. The use of PUFA is recommended and was safe in the atopic study dogs receiving oclacitinib.
Economic evaluations of neglected tropical disease interventions in low- and middle-income countries: a systematic review protocol
Authors: Mahapatra Biswajit , Mukherjee Nirmalya , Khatoon Sajda , Bhattacharya Paramita , Das Pritha , Bharti Omesh , John Denny 
Published: March 2024

Objective:
The objective of this systematic review is to provide an overview of economic evaluation studies of interventions for neglected tropical diseases in low- and/or middle-income countries.

Introduction:
The majority of people most susceptible to neglected tropical diseases reside in low- and middle-income countries and suffer significant economic impact due to these diseases. The World Health Organization suggests utilizing a systematic and cross-cutting approach with multiple interventions to lessen the neglected tropical disease burden.

Inclusion criteria:
Studies will be eligible for inclusion if they include economic evaluations of interventions for neglected tropical diseases and are conducted in low- and/or middle-income country settings.

Methods:
A preliminary search of MEDLINE (PubMed) was undertaken using MeSH terms, such as neglected tropical disease, economic evaluation, therapeutics, low- and/or middle-income countries. Two reviewers will screen titles and abstracts independently, followed by a full-text review against the inclusion criteria. Disagreements will be resolved by discussion or with a third reviewer. To assess methodological quality, the JBI checklist for economic evaluations will be used. For economic evaluations, data will be extracted using the standardized JBI data extraction form. The Dominance Ranking Matrix will be used to summarize and compare the results of different types of economic evaluations. Cost per quality adjusted life year gained and cost per disability adjusted life year averted will be measures for economic evaluation. The Grading of Recommendations Assessment, Development and Evaluation (GRADE) approach will be used to assess the certainty of economic evidence, such as resource use and costs.

Review registration:
PROSPERO CRD42017070386
Predicting the Performance of Turbine Exhaust Diffuser-Collector Systems Across the Operating Range: Comparison of Lattice-Boltzmann Method Simulations With Experiments
Authors: Langford Matthew , Siorek Michal , Guillot Stephen , Ng Wing F. 
Published: March 2024

Abstract
The predictive capability of the lattice-Boltzmann very large eddy simulation (LBM-VLES) methodology was evaluated for industrial gas turbine exhaust diffuser-collector applications. The effort focused on evaluating the accuracy of performance predictions against experimental rig data gathered at engine representative conditions including the Reynolds number, Mach number, and inlet flow conditions. The performance prediction capability of LBM-VLES simulations was also compared against Reynolds-averaged Navier–Stokes (RANS) simulations. Evaluations were completed for two distinct exhaust rig geometries at conditions indicative of their respective design points, and the performance prediction capability was also evaluated at conditions depicting two off-design cases. The off-design conditions were represented by an increase in inlet swirl angle and associated incidence on the diffuser struts. Overall, the authors found that LBM-VLES simulations were a suitable approach for predicting the performance of gas turbine exhaust diffuser-collector systems at both on- and off-design conditions. The LBM-VLES simulation accuracy was substantially better than that achieved by RANS simulations, with 66% lower RMS pressure recovery error between computational fluid dynamics (CFD) and experiments for the four cases studied, and an 89% reduction in error for the furthest off-design case. The computational cost of the transient LBM-VLES simulations was roughly the same as the RANS simulations performed using best practices for that solver.
Non-
faecium
non-
faecalis
enterococci: a review of clinical manifestations, virulence factors, and antimicrobial resistance
Authors: Mullally Christopher A. , Fahriani Marhami , Mowlaboccus Shakeel , Coombs Geoffrey W. 
Published: March 2024

SUMMARY

Enterococci are a diverse group of Gram-positive bacteria that are typically found as commensals in humans, animals, and the environment. Occasionally, they may cause clinically relevant diseases such as endocarditis, septicemia, urinary tract infections, and wound infections. The majority of clinical infections in humans are caused by two species:
Enterococcus faecium
and
Enterococcus faecalis
. However, there is an increasing number of clinical infections caused by non-
faecium
non-
faecalis
(NFF) enterococci. Although NFF enterococcal species are often overlooked, studies have shown that they may harbor antimicrobial resistance (AMR) genes and virulence factors that are found in
E. faecium
and
E. faecalis
. In this review, we present an overview of the NFF enterococci with a particular focus on human clinical manifestations, epidemiology, virulence genes, and AMR genes.
Complete genome sequence of
Selenomonas species
strain TAMA-11512, isolated from blood culture of a septic patient
Authors: Horiba Kazuhiro , Aso Sakura , Oda Rentaro , Tateishi Yoshinori , Ura Kuniko , Kuroda Makoto 
Published: March 2024

ABSTRACT

We report the complete sequence of
Selenomonas
species strain TAMA-11512, isolated from the blood culture of a septic patient. The phylogeny and average nucleotide identity show that the strain TAMA-11512 is considered a novel bacterial species in
Selenomonas
genus.
Rich microbial and depolymerising diversity in Antarctic krill gut
Authors: Möller Lars , Vainshtein Yevhen , Meyer Bettina , Neidhardt John , Eren A. Murat , Sohn Kai , Rabus Ralf 
Published: March 2024

ABSTRACT

With almost a quadrillion individuals, the Antarctic krill processes five million tons of organic carbon every day during austral summer. This high carbon flux requires a broad range of hydrolytic enzymes to decompose the diverse food-derived biopolymers. While krill itself possesses numerous such enzymes, it is unclear, to what extent the endogenous microbiota contribute to the hydrolytic potential of the gut environment. Here we applied amplicon sequencing, shotgun metagenomics, cultivation, and physiological assays to characterize the krill gut microbiota. The broad bacterial diversity (273 families, 919 genera, and 2,309 species) also included a complex potentially anaerobic sub-community. Plate-based assays with 198 isolated pure cultures revealed widespread capacities to utilize lipids (e.g., tributyrin), followed by proteins (casein) and to a lesser extent by polysaccharides (e.g., alginate and chitin). While most isolates affiliated with the genera
Pseudoalteromonas
and
Psychrobacter
, also
Rubritalea
spp. (Verrucomicrobia) were observed. The krill gut microbiota growing on marine broth agar plates possess 13,012 predicted hydrolyses; 15-fold more than previously predicted from a transcriptome-proteome compendium of krill. Cultivation-independent and -dependent approaches indicated members of the families
Flavobacteriaceae
and
Pseudoalteromonadaceae
to dominate the capacities for lipid/protein hydrolysis and to provide a plethora of carbohydrate-active enzymes, sulfatases, and laminarin- or porphyrin-depolymerizing hydrolases. Notably, also the potential to hydrolyze plastics such as polyethylene terephthalate and polylactatide was observed, affiliating mostly with Moraxellaceae. Overall, this study shows extensive microbial diversity in the krill gut, and suggests that the microbiota likely play a significant role in the nutrient acquisition of the krill by enriching its hydrolytic enzyme repertoire.

IMPORTANCE

The Antarctic krill (
Euphausia superba
) is a keystone species of the Antarctic marine food web, connecting the productivity of phyto- and zooplankton with the nutrition of the higher trophic levels. Accordingly, krill significantly contributes to biomass turnover, requiring the decomposition of seasonally varying plankton-derived biopolymers. This study highlights the likely role of the krill gut microbiota in this ecosystem function by revealing the great number of diverse hydrolases that microbes contribute to the krill gut environment. The here resolved repertoire of hydrolytic enzymes could contribute to the overall nutritional resilience of krill and to the general organic matter cycling under changing environmental conditions in the Antarctic sea water. Furthermore, the krill gut microbiome could serve as a valuable resource of cold-adapted hydrolytic enzymes for diverse biotechnological applications.
Extended gravitational vortex without dark matter
Authors: Ludwig G. O. 
Published: March 2024

AbstractThis paper analyzes, within the extended gravitoelectromagnetic (GEM) formulation, the equilibrium of a large scale gravitational system formed by rotating dust. The force balance equation gives the rotation velocity in terms of the GEM fields. Boundary conditions for the fields are introduced using Helmholtz’s decomposition and the virtual casing principle. Hydro-gravitomagnetic Cauchy invariance is implemented to relate the fluid and gravitomagnetic field vorticities. An energy conservation equation gives the rotation velocity in terms of the gravitational field and respective boundary values. A detailed solution is calculated for the case of rotating oblate spheroids. The equilibrium is in the form of a sheared rotational vortex, without introducing dark matter. The results are consistent with the Tully–Fisher relation and the Virginia Trimble correlations.
The Novel ATR Inhibitor Tuvusertib (M1774) Induces Replication Protein Overexpression and Broad Synergy with DNA-targeted Anticancer Drugs
Authors: Jo Ukhyun , Arakawa Yasuhiro , Zimmermann Astrid , Taniyama Daiki , Mizunuma Makito , Jenkins Lisa M. , Maity Tapan K. , Kumar Suresh , Zenke Frank T. , Takebe Naoko , Pommier Yves 
Published: March 2024

Abstract
Ataxia telangiectasia and Rad3-related (ATR) checkpoint kinase inhibitors are in clinical trials. Here we explored the molecular pharmacology and therapeutic combination strategies of the oral ATR inhibitor tuvusertib (M1774) with DNA-damaging agents (DDAs). As single agent, M1774 suppressed cancer cell viability at nanomolar concentrations, showing greater activity than ceralasertib and berzosertib, but less potency than gartisertib and elimusertib in the small cell lung cancer H146, H82, and DMS114 cell lines. M1774 also efficiently blocked the activation of the ATR-CHK1 checkpoint pathway caused by replication stress induced by TOP1 inhibitors. Combination with non-toxic dose of M1774 enhanced TOP1 inhibitor-induced cancer cell death by enabling unscheduled replication upon replicative damage, thereby increasing genome instability. Tandem mass tag-based quantitative proteomics uncovered that M1774, in the presence of DDA, forces the expression of proteins activating replication (CDC45) and G2−M progression (PLK1 and CCNB1). In particular, the fork protection complex proteins (TIMELESS and TIPIN) were enriched. Low-dose of M1774 was found to be highly to be synergistic with a broad spectrum of clinical DDAs including TOP1 inhibitors (SN-38/irinotecan, topotecan, and exatecan), the TOP2 inhibitor etoposide, cisplatin, the RNA polymerase II inhibitor lurbinectedin, and the PARP inhibitor talazoparib in various models including cancer cell lines, patient-derived organoids, and mouse xenograft models. Furthermore, we demonstrate that M1774 reverses chemoresistance to anticancer DDAs in cancer cells lacking SLFN11 expression, suggesting that SLFN11 can be utilized for patient selection in upcoming clinical trials.
Alpha-180 spin-echo-based line-scanning method for high-resolution
laminar-specific fMRI in animals
Authors: Choi Sangcheon , Hike David , Pohmann Rolf , Avdievich Nikolai , Gomez-Cid Lidia , Man Weitao , Scheffler Klaus , Yu Xin 
Published: March 2024

Abstract
Laminar-specific functional magnetic resonance imaging (fMRI) has been widely used to study circuit-specific neuronal activity by mapping spatiotemporal fMRI response patterns across cortical layers. Hemodynamic responses reflect indirect neuronal activity given the limitation of spatial and temporal resolution. Previously, a gradient-echo-based line-scanning fMRI (GELINE) method was proposed with high temporal (50 ms) and spatial (50 µm) resolution to better characterize the fMRI onset time across cortical layers by employing two saturation RF pulses. However, the imperfect RF saturation performance led to poor boundary definition of the reduced region of interest (ROI) and aliasing problems outside of the ROI. Here, we propose an α (alpha)-180 spin-echo-based line-scanning fMRI (SELINE) method in animals to resolve this issue by employing a refocusing 180˚ RF pulse perpendicular to the excitation slice (without any saturation RF pulse) and also achieve high spatiotemporal resolution. In contrast to GELINE signals which peaked at the superficial layer, we detected varied peaks of laminar-specific BOLD signals across deeper cortical layers using the SELINE method, indicating the well-defined exclusion of the large draining-vein effect using the spin-echo sequence. Furthermore, we applied the SELINE method with a 200 ms repetition time (TR) to sample the fast hemodynamic changes across cortical layers with a less draining vein effect. In summary, this SELINE method provides a novel acquisition scheme to identify microvascular-sensitive laminar-specific BOLD responses across cortical depth.
Re-enchanting Paul?
Authors: Potgieter Annette 
Published: March 2024

Abstract
The Galatian community is disrupted with different notions of the gospel than Paul intended. Paul, surprised that this community is confused so easily, sets out in Gal 3 to explain what justification by faith entails. Paul and his letter to the Galatians are products of a first century CE context. The problem when faced with Galatians, particularly Gal 3:1–14, is that research on rhetoric abounds, but the curse language, which is an embedded in Paul’s context is often dismissed or ignored. My focus here is to trace Paul’s meaning, specifically focusing on curse language in the argument of Gal 3 in order to show that Paul is embedded in a apotropaic imaginary as befits his socio-cultural setting and Greco-Roman discursive reality.
Relationship between the Uncertainty of Empirical Orthogonal Function (EOF) Modes and Sampling Sizes in Climate Models
Authors: Shen Tong , Lu Riyu 
Published: March 2024

Abstract
This study investigates the relationship between the uncertainty of empirical orthogonal function (EOF) modes and sampling size in climate models, using simulated results of preindustrial control (piControl) experiments in phase 6 of the Coupled Model Intercomparison Project (CMIP6), and taking the North Atlantic Oscillation (NAO) and El Niño–Southern Oscillation (ENSO) as examples. The results indicate that this relationship can be quantified by a concise fitting function [i.e., y = a/(x − b)]. Here, y is the 5%–95% confidence interval of congruence coefficient, x is the sampling size, and a and b are two parameters depending on models or observations. As compared with b, which modulates the sampling size in the fitting function, the parameter a scales the sampling size and thus plays a much more important role. Further analysis indicates that the parameter a, or the uncertainty of EOF1 mode, decreases dramatically with the increase of the difference between variance fractions of EOF1 and EOF2 modes, approximately in the form of a power function. The minimum sampling size to ensure a reliable EOF mode can also be estimated by the fitting function and shows a great diversity among models both for the NAO and ENSO. The diversity suggests the importance of estimating the minimum sampling size before model evaluations on climate variability modes and projections on the future change in modes, particularly when the EOF2 mode explains the variance close to EOF1 mode.

Significance Statement
Empirical orthogonal function (EOF) analysis, principal component analysis, or eigenvector analysis has been widely used in various research fields. However, it remains as an open question as to how large the sampling size is required to be to obtain reliable modes through the EOF method. In this study, we investigate the relationship between the uncertainty of EOF results and sampling size in current climate models, using adequately long simulated data, and we find that this relationship can be depicted by the fitting function y = a/(x − b). Here, y represents the uncertainty, x is the sampling size, and a and b are parameters. The parameter a is closely related to the difference between variance fractions of first and second EOF modes and plays a more important role in the fitting function. The minimum sampling sizes that are required to obtain reliable EOF modes can also be estimated by the fitting function and vary greatly from model to model. The results provide a basis for judging the reliability of EOF modes, particularly when the first and second EOF modes explain similar variance fractions.