bluuebunny/crossref_metadata_2025_split huggingface dataset:
Reclassification of aggressive adenomatous mastoid neoplasms as endolymphatic sac tumors
Authors: Li John C. , Brackmann Derald E. , House John W. , Lo William W. M. , Carberry Joseph N. 
Published: October 2006

AbstractThe emerging concept that aggressive adenomatous tumors of the temporal bone arise from the endolymphatic sac and constitute a distinct clinico‐pathologic entity merits wider recognition. These tumors share a common clinical pattern and exhibit consistent imaging and histopathologic features. Endolymphatic sac tumors (ELSTs) have been mistaken for other neoplasms such as paragangliomas, adenomatous tumors of mixed histology, ceruminomas, and choroid plexus papillomas. A review of the literature shows similarities among case studies of these aggressive adenomatous lesions. An analysis of the data supports the endolymphatic sac as an origin for these tumors. This report also presents an additional case of a less differentiated variant of this rare but important clinicopathologic entity.
Development of the South African wastewater sludge guidelines
Authors: Snyman H.G. , van Niekerk A.M. , Herselman E. , Wilken J.W. 
Published: October 2006

The new South African Wastewater Sludge Guideline Series will replace the document entitled: “Permissible Utilisation and Disposal of Sewage Sludge, Edition 1, 1997” which deals with application of sewage sludge to land.
The new guideline series will be published as 5 volumes:Volume 1: Management Options for the Use or Disposal of Wastewater SludgeVolume 2: Requirements for the agricultural use of wastewater sludgeVolume 3: Requirements for the on site and off-site disposal of wastewater sludgeVolume 4: Requirements for the use of wastewater sludge in the production of commercial productsVolume 5: Requirements for the incineration of wastewater sludgeWe envisage that Volumes 1 and 2 will be published at the time of the conference and that work has begun on Volume 3, 4 and 5. The paper aims to communicate the major differences between the previous sludge guidelines and these new sludge guideline series. For example, the paper details the new wastewater sludge classification system and the requirements for the characterisation of the sludge for classification purposes. The paper will also explain the approach followed in the development of Volume 1 and 2 and will elaborate on the proposed approach for Volumes 3, 4 and 5.
Measurement of the Concentration of Radon Gas in the Toirano's Caves (Liguria)
Authors: Bruzzone Diego , Bussallino Massimo , Castello Gianrico , Maggiolo Stefano , Rossi Daniela 
Published: October 2006

AbstractThe radioactive gas radon, intermediate term of the decay series of uranium and thorium, is the main contamination source of underground places and may be a risk for high concentration and long exposure time. European and Italian law requires radon concentration to be measured in workplaces and, if the “action level” of 500 Bq/m3 is reached, proper actions must be made in order to decrease the dose commitment. Considering natural showcaves or artificial cavities open to public, the exposition of the visitors is frequently small, due to the short residence time, but accompanying people, remaining underground for long time, may be subject to appreciable dose and the radon concentration should therefore be monitored. The high humidity in natural caves may impair the use of some measuring devices. Therefore, different detection methods were compared (ZnS scintillation counters, E‐PERM electret ionisation chambers, cellulose nitrate alpha‐track dosimeters) to select the best procedure for long‐term investigation. The LR‐115 (Kodak) alpha‐track dosimeters were insensitive to humidity and permitted to monitor a great number of places at the same time. Measurements have been carried out in the speleological and archaeological site of the Toirano's Caves (Savona, Liguria, Italy) and several points were monitored for two years. Radon concentration strongly depends on the site and changes during the year, due to the difference between internal and external temperature. The maximum dose commitment during the visitors tour, considering the average yearly value of radon concentration, was found to be between 1.5 and 4 μSv. It was found that no risk exists for visitors, but the evaluation of the dose absorbed by the guides and their classification according to the radiation protection law requires a complete monitoring of the average yearly concentration of radon and of the total time spent by each worker into the cave.
Methodology and Application of GC‐MS to Study Altered Organic Binding Media from Objects of the Kunsthistorisches Museum, Vienna
Authors: Pitthard Václav , Griesser Martina , Stanek Sabine 
Published: October 2006

AbstractWithin the Kunsthistorisches Museum (KHM), Vienna, three off‐line GC‐MS analytical procedures for the identification of natural organic media have been refined, tested, and validated on a series of reference materials (partly artificially aged) to apply this knowledge for investigations of original, historic works of art from the museum's collections. At first, a set of artificially aged mock‐ups has been prepared and a reference database has been built up for the identification of drying oils, resins, waxes, proteins and polysaccharides. Some interesting observations concerning the alteration of the composition of these organic media during different ageing steps are presented in the following text. In addition, some selected examples for the application of the refined techniques for the analysis of real samples from various museum objects are shown.
Parietal bone agenesis with gracile bones and splenic hypoplasia/aplasia: Clinico‐pathologic report and differential diagnosis with review of cranio‐gracile bone syndromes, “osteocraniostenosis” and Kleeblattschädel
Authors: Spear Gerald S. 
Published: October 2006

AbstractThe findings in a newborn male with agenesis of parietal bones, gracile long bones, and hypoplasia of the spleen are presented. Although parietal agenesis is unique, the findings are compatible with 18 previously reported cases characterized by cranial hypomineralization, Kleeblatschädel, gracile bones, and splenic aplasia/hypoplasia, the nomenclature for which has been descriptive: gracile bone disorders, “osteocraniostenosis,” “osteocraniosplenic syndrome.” The term “osteocraniostenosis” may be inappropriate in that craniostenosis has been infrequently reported, a feature also of importance with respect to the pathogenesis of the Kleeblatschädel. The group likely reflects heterogeneous etiology and pathogenesis. Precedent, however, including animal models, justifies consideration of genetic aberrations, in particular, mutations in homeobox genes. © 2006 Wiley‐Liss, Inc.
V37I connexin 26 allele in patients with sensorineural hearing loss: Evidence of its pathogenicity
Authors: Huculak C. , Bruyere H. , Nelson T. N. , Kozak F. K. , Langlois S. 
Published: October 2006

AbstractSensorineural hearing loss (SNHL) is the most common inherited sensory disorder, reported in 1–3 of every 1,000 births. It has been estimated that 50% of all cases of prelingual SNHL are genetically determined. There is tremendous genetic heterogeneity, with multiple dominant and recessive loci. Mutations of the gap junction beta‐2 gene (GJB2) emerge as a leading cause of autosomal recessive non‐syndromic SNHL. Over 90 sequence alterations have been reported, the pathogenicity of some of them being unknown or unclear. The status of the V37I allele of connexin 26 (GJB2 amino acid product) with regards to its association with SNHL has been controversial. This study examines the pathogenicity of V37I by comparing the frequency of this allele in 40 patients with SNHL of Chinese and Caucasian descent with the frequency of the allele in 100 anonymized, ethnically matched controls. The V37I allele was identified in 43.75 and 11.5% of the patient and control alleles of Chinese ethnicity, respectively, but was not found in either Caucasian cohort. We also compiled the audiograms of 15 individuals with SNHL homozygous for the V37I allele, and showed that these individuals present with a mild to moderate SNHL. These results indicate that (1) the V37I allele is common in individuals of Chinese descent but rarely present in individuals of Caucasian decent; and (2) the V37I allele is pathogenic, but produces milder hearing loss compared to nonsense mutations of connexin 26 such as the 35delG mutation. © 2006 Wiley‐Liss, Inc.
Deaths due to choking in Prader–Willi syndrome
Authors: Stevenson David A. , Heinemann Janalee , Angulo Moris , Butler Merlin G. , Loker Jim , Rupe Norma , Kendell Patrick , Clericuzio Carol L. , Scheimann Ann O. 
Published: October 2006

AbstractPrader–Willi syndrome (PWS) is the most common known syndromic cause of life‐threatening obesity, yet few studies have examined the causes of death in PWS. The objective of this study was to examine the contribution of choking leading to mortality in PWS. In 1999, a brief survey was made available from the Prader–Willi Syndrome Association (USA) bereavement program, which documented demographic data and causes of death. Families were subsequently offered the opportunity to fill out a detailed questionnaire and additional forms to release medical records. Demographic information was available on 178 deceased individuals with PWS, and cause of death available on 152 individuals. Fifty‐four families completed questionnaires. Of the deceased individuals with completed questionnaires, 34% reported a history of choking. Choking was listed by familial report as the cause of death in 12 (7.9%) of 152 subjects with an average age of 24 years (range 3–52 years; median 22.5 years) at death from choking. Only two of these individuals were less than 8 years of age. The data suggest that risks associated with choking are different in the PWS population compared with others. Potential causes of increased choking in PWS include poor oral/motor coordination, poor gag reflex, hypotonia, hyperphagia, decreased mastication, and voracious feeding habits. We recommend implementation of preventive measures and education for families and group home care providers for all individuals with PWS including the Heimlich maneuver, supervised meals, better food preparation, and diet modification to avoid high‐risk choking items. © 2006 Wiley‐Liss, Inc.
CLN3P, the Batten's disease protein, is a novel palmitoyl‐protein Δ‐9 desaturase
Authors: Narayan Srinivas B. , Rakheja Dinesh , Tan Lu , Pastor Johanne V. , Bennett Michael J. 
Published: October 2006

AbstractObjectiveBatten's disease, one of the most common recessively inherited, untreatable, neurodegenerative diseases of humans, is characterized by progressive neuronal loss and intraneuronal proteolipid storage. Although the gene for the disorder was cloned more than a decade ago, the function of the encoded protein, CLN3P, has not been defined thus far.MethodsSequence analysis using the Pfam server identified a low stringency match to a fatty acid desaturase domain in the N‐terminal sequence of CLN3P. We developed a fatty acid desaturase assay based on measurement of desaturase products by gas chromatography/mass spectrometry.ResultsWe show that CLN3P is a novel palmitoyl‐protein Δ‐9 desaturase, which converts membrane‐associated palmitoylated proteins to their respective palmitoleated derivatives. We have further demonstrated that this palmitoyl‐protein Δ‐9 desaturase activity is deficient in cln3−/− mouse pancreas and is completely ablated in neuroblastoma cells by RNA inhibition.InterpretationWe propose that palmitoyl‐protein desaturation defines a new mechanism of proteolipid modification, and that deficiency of this process leads to the signs and symptoms of Batten's disease. Ann Neurol 2006
Metallomacrocycles That Incorporate Cofacially Aligned Diimide Units
Authors: Khoshbin Meisa S. , Ovchinnikov Maxim V. , Salaita Khalid S. , Mirkin Chad A. , Stern Charlotte L. , Zakharov Lev N. , Rheingold Arnold L. 
Published: October 2006

AbstractPyromellitic diimide and naphthalene diimide moieties were incorporated into hemilabile phosphanylalkyl thioether ligands. These ligands reacted with [Cu(CH3CN)4]PF6 and [Rh(NBD)Cl]2 (NBD=norbornadiene) by the weak‐link approach to form condensed intermediates. Upon reaction of each diimide ligand with these transition‐metal precursors, the two diimide units became cofacially aligned within a supramolecular macrocyclic architecture. The introduction of ancillary ligands to each of these condensed intermediates caused the weak thioether–metal bonds to break, thus generating a large macrocycle in which the distance between diimide units is significantly larger than for the condensed intermediates. The two RhI cationic condensed intermediates were characterized by single‐crystal X‐ray diffraction studies, and the electrochemical activity of these macrocycles was demonstrated with the naphthalene diimide–CuI macrocycles.
Incorporating genetic analyses into birth defects cluster investigations: Strategies for identifying candidate genes
Authors: Green Ridgely Fisk , Moore Cynthia 
Published: October 2006

AbstractBACKGROUND: Incorporating genetic analyses into birth defect cluster investigations may increase understanding of both genetic and environmental risk factors for the defect. Current constraints of most birth defect cluster investigations make candidate gene selection the most feasible approach. Here, we describe strategies for choosing candidate genes for such investigations, which will also be applicable to more general gene‐environment studies. METHODS: We reviewed publicly available web‐based resources for selection of candidate genes and identification of risk factors, as well as publications on different strategies for candidate gene selection. RESULTS: Candidate gene selection requires consideration of available gene‐disease databases, previous epidemiological studies, animal model research, linkage and expression studies, and other resources. We describe general considerations for utilizing available resources, as well as provide an example of a search for candidate genes related to gastroschisis. CONCLUSIONS: Available web resources could facilitate selection of candidate genes, but selection of optimal candidates will still require a strong understanding of genetics and the pathogenesis of the defect, as well as careful consideration of previous epidemiological studies. Birth Defects Research (Part A) 2006. © 2006 Wiley‐Liss, Inc.
Efficacy of intracoronary nicardipine in the treatment of no‐reflow during percutaneous coronary intervention
Authors: Huang Raymond I. , Patel Parul , Walinsky Paul , Fischman David L. , Ogilby J. David , Awar Mark , Frankil Craig , Savage Michael P. 
Published: October 2006

AbstractObjectives: The goal of this study was to evaluate the safety and efficacy of nicardipine in reversing no‐reflow during percutaneous coronary intervention (PCI). Background: No‐reflow is a common complication of PCI in patients with acute coronary syndromes or venous bypass graft disease. Although nicardipine has an attractive pharmacological profile and has been used clinically to treat no‐reflow, there is a paucity of published data regarding its effectiveness in this setting. Methods: We conducted a retrospective analysis of 72 consecutive patients who received intracoronary nicardipine to reverse no‐reflow during coronary intervention. Qualitative TIMI flow grade and quantitative TIMI frame count methods were used to assess the efficacy of nicardipine. Results: A mean of 460 ± 360 mcg of intracoronary nicardipine was used. No‐reflow was successfully reversed with complete restoration of TIMI 3 flow in 71 of 72 patients (98.6%). TIMI flow grade improved from 1.65 ± 0.53 prior to nicardipine to 2.97 ± 0.24 after treatment (P < 0.001). TIMI frame count decreased from 57 ± 40 at the time of no‐reflow to 15 ± 12 after nicardipine administration (P < 0.001). Nicardipine therapy was well tolerated without adverse hemodynamic or chronotropic effects.Conclusions: In this largest series to date, intracoronary nicardipine was demonstrated to be a safe and highly effective pharmacological agent to reverse no‐reflow during PCI. © 2006 Wiley‐Liss, Inc.
Investigations on Iodomercurates: Crystal Structures of Bis‐tetramethylammonium Tetraiodomercurate(II), Tetramethylammonium Pentaiododimercurate(II) and Bis[di(12‐crown‐4)lithium]decaiodotetramercurate(II).
Authors: Pickardt Joachim , Wiese Sven , Borowski Marina 
Published: October 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Excitation Intensity and Temperature‐Dependent Photoluminescence and Optical Absorption in Tl4Ga3InSe8 Layered Crystals.
Authors: Goksen K. , Gasanly N. M. , Turan R. 
Published: October 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Crystal Structure and Magnetic Properties of Tb6FeSb2.
Authors: Cai Gemei , Zhang Jiliang , He Wei , Qin Pingli , Zeng Lingmin 
Published: October 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Giant Magnetocaloric Effect Enhanced by Pd‐Doping in Gd5Si2Ge2 Compound.
Authors: Zhuang Y. H. , Li J. Q. , Huang W. D. , Sun W. A. , Ao W. Q. 
Published: October 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Reaction Between LiF and MF5 (M: Ta, Nb) in a Fluorine Atmosphere.
Authors: Kim Jae‐Ho , Yonezawa Susumu , Takashima Masayuki 
Published: October 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
SnCl2×2H2O — An Alternative to Lewis Acidic Ionic Liquids.
Authors: Arumugam Pandurangan , Perumal Paramasivan T. 
Published: October 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Indirect Cation Pool Method. Rapid Generation of Alkoxycarbenium Ion Pools from Thioacetals.
Authors: Suga Seiji , Matsumoto Kouichi , Ueoka Koji , Yoshida Jun‐ichi 
Published: October 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Catalytic Removal of N‐Allyloxycarbonyl Groups Using the [CpRu(IV)(π‐C3H5)(2‐quinolinecarboxylato)] PF6 Complex. A New Efficient Deprotecting Method in Peptide Synthesis.
Authors: Tanaka Shinji , Saburi Hajime , Murase Takanori , Yoshimura Masahiro , Kitamura Masato 
Published: October 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
One‐Step Deprotonation Route to Zinc Amide and Ester Enolates for Use in Aldol Reactions and Negishi Couplings.
Authors: Hlavinka Mark L. , Hagadorn John R. 
Published: October 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Novel Synthetic Methodologies. Part 87. (Bromodimethyl)sulfonium Bromide Catalyzed Efficient Multicomponent One‐Pot Synthesis of Homoallylic Amines.
Authors: Das Biswanath , Ravikanth B. , Thirupathi P. , Rao B. Vittal 
Published: October 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Reactivity of γ‐Chloro‐gem‐trichloroalkanes with Chromous Chloride.
Authors: Tisserand Steve , Bejot Romain , Billaud Celia , Li De Run , Falck J. R. , Mioskowski Charles 
Published: October 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Highly Stereoselective One‐Pot Synthesis of Tetrasubstituted Alkenes via Carbopalladation Reaction of Fluorine‐Containing Acetylene Derivatives.
Authors: Konno Tsutomu , Taku Ken‐ichi , Ishihara Takashi 
Published: October 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Palladium‐Catalyzed Cross‐Coupling of Vinylic Tellurides and Potassium Vinyltrifluoroborate Salt: Synthesis of 1,3‐Dienes.
Authors: Cella Rodrigo , Orfao Aline T. G. , Stefani Helio A. 
Published: October 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Copper‐, Ligand‐ and Solvent‐Free Synthesis of Ynones by Coupling Acid Chlorides with Terminal Alkynes.
Authors: Palimkar Sanjay S. , Kumar P. Harish , Jogdand Nivrutti R. , Daniel Thomas , Lahoti Rajgopal J. , Srinivasan Kumar V. 
Published: October 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
General Synthesis of 8‐Aryl‐2‐tetralones.
Authors: Carreno M. Carmen , Gonzalez‐Lopez Marcos , Latorre Alfonso , Urbano Antonio 
Published: October 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Pd‐Catalyzed Ring Opening of Oxa‐ and Azabicyclic Alkenes with Aryl and Vinyl Halides: Efficient Entry to 2‐Substituted 1,2‐Dihydro‐1‐naphthols and 2‐Substituted 1‐Naphthols.
Authors: Chen Chi‐Li , Martin Stephen F. 
Published: October 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Stereoselective Construction of 3a‐Methylhydrindans Starting from 2,7‐Enynol Derivatives Based on Ti(II)‐Mediated Cyclization and Ru‐Catalyzed Ring‐Closing Metathesis.
Authors: Ohkubo Mutsumi , Uchikawa Wataru , Matsushita Hitomi , Nakano Aiko , Shirato Takayuki , Okamoto Sentaro 
Published: October 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Studies on Epoxidation of Enantiomerically Pure 2,3‐Dideoxy Hex‐2‐enitols: A Convenient Access to Highly Functionalized Enantiomerically Pure Tetrahydrofuran Derivatives.
Authors: Sagar Ram , Reddy L. Vijaya Raghava , Shaw Arun K. 
Published: October 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Palladium‐Catalyzed Intramolecular Cyanoamidation of Alkynyl and Alkenyl Cyanoformamides.
Authors: Kobayashi Yusuke , Kamisaki Haruhi , Yanada Reiko , Takemoto Yoshiji 
Published: October 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.