bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effect of a topical vasoconstrictor on computed tomography of paranasal sinus disease
Authors: Mancuso Anthony A. , Stringer Scott P. , Avino Anthony J. 
Published: October 2006

AbstractApparent ethmoid inflammation which resolved with alternation of the nasal cycle or following application of topical vasoconstrictors has been observed with magnetic resonance imaging. A similar phenomenon might occur to a lesser degree with computed tomography (CT), leading to overdiagnosis of limited sinus disease. The degree to which ostiomeatal complex disease is reversible by topical vasoconstrictors was investigated. Ten patients with histories of chronic or recurrent sinusitis underwent coronal CT studies of the paranasal sinuses before and after the application of a topical vasoconstrictor. Mucosal volume or thickness measurements were obtained from the turbinates, infundibulum, ethmoidal cells, and antrum. Vasoconstrictor application markedly reduced turbinate size and appeared to reduce mucosal thickening in the ethmoidal infundibulum. Minimal mucosal changes identified in the paranasal sinuses by computed tomography were not reversed by vasoconstrictors and therefore are likely to be pathologic.
Drug‐Induced, life‐threatening angioedema revisited
Authors: Thompson Tab , Frable Mary Ann Smith 
Published: October 2006

AbstractFew drug reactions are more life threatening than the sudden development of edema involving the mucosal and submucosal layers of the upper aerodigestive tract. Drug‐induced angioedema is a recognized entity of angiotensin‐converting enzyme (ACE) inhibitors, and despite reports in medical journals and drug insert warnings, captopril and enalapril continue to be widely prescribed. As these drugs are efficacious and usually well‐tolerated in the treatment of mild forms of hypertension, their popularity is rising.From June 1, 1984 to August 1, 1991, 36 patients with angioedema secondary to ACE inhibitors presented at the Medical College of Virginia Hospitals. Thirty were successfully managed with medical therapy. Two were intubated, 1 had placement of a nasal trumpet, and 3 required tracheostomies.Of extreme importance is the recognition that angioedema resulting from ACE inhibitors is probably not immunoglobulin E (IgE) mediated and that antihistaminics and steroids may not alleviate the airway obstruction. The otolaryngologist must be prepared for the need of possible early surgical intervention.
Blastomycosis in otolaryngology: Review of a large series
Authors: Reder Paul A. , Neel H. Bryan 
Published: October 2006

AbstractBlastomycosis is a fungal disease whose signs, symptoms, and roentgenographs findings may suggest pneumonia, cancer, tuberculosis, or other fungal infections. Blastomycosis has a variable clinical course; it primarily affects the lower respiratory tract, although extrapulmonary manifestations are common. To determine the frequency of head and neck manifestations, we reviewed the records of patients with blastomycosis seen at the Mayo Clinic from 1960 to 1990 and found that involvement of the skin and mucosal surfaces, including the larynx, was common. Gross and histopathologic features of the lesions often resemble those of well‐differentiated squamous cell carcinoma; thus, overly aggressive therapy may be mistakenly instituted.The clinical features, morphologic findings, and diagnosis of blastomycosis are discussed, and the importance of obtaining and handling specimens correctly is emphasized.
Peripheral hearing loss following head trauma in children
Authors: Zimmerman William D. , Ganzel Toni M. , Windmill Ian M. , Phillips Michele , Nazar Gregory B. 
Published: October 2006

AbstractThe purpose of this prospective study was to determine the incidence and type of hearing loss occurring in children who suffered head injuries. Fifty children admitted to the neurosurgical service after sustaining head trauma were studied. Neurologic, otologic, and audiologic evaluations were performed. Diagnostic studies included skull roentgenograms and computerized tomography scans. A 32% incidence of conductive hearing loss and a 16% incidence of high‐frequency sensorineural hearing loss was found in this group. All patients with temporal bone fractures had conductive hearing losses, but the presence of a skull vault fracture did not correlate with the presence, type, or degree of hearing loss. In addition, there was no correlation between either cause of injury, loss of consciousness, or Glasgow Coma Scale scores and the presence, type, or degree of hearing loss. There was a significant incidence of both sensorineural and conductive hearing loss in this series of patients, which indicates that close audiologic and otologic follow‐up is necessary for all head injury patients.
Surgery for vertigo in the nonserviceable hearing ear: Transmastoid labyrinthectomy or translabyrinthine vestibular nerve section
Authors: Langman Alan W. , Lindeman Roger C. 
Published: October 2006

AbstractTwo of the surgical options that exist for the treatment of disabling vertigo arising from an ear with nonserviceable hearing are a transmastoid lab‐yrinthectomy (TL) and a translabyrinthine vestibular nerve section (TLVNS). The major difference between the two operations is a section of the vestibular nerves with the TLVNS which removes all preganglionic vestibular tissue from the diseased inner ear. It has been inferred that a TLVNS should be the procedure of choice if hearing is not to be spared, because a TL results in an incomplete removal of preganglionic vestibular tissue, and that this remaining tissue might have continued or recurrent physiologic function resulting in further vertigo. The clinical outcome of 58 patients who had either TL or TLVNS for disabling vertigo arising from a nonserviceable hearing ear was investigated with respect to the control of vertigo and the development of postoperative balance dysfunction. The control of vertigo in the TLVNS and TL groups was 100% and 95.3%, respectively. This difference was not statistically significant. There was a tendency for postoperative dys‐equilibrium to be more frequent in the TLVNS group, but this finding did not reach statistical significance. A TL appears to offer the same benefit as TLVNS in the control of intractable episodic vertigo without the additional risks of TLVNS.
Clinical signs of orbital ischemia in rhino‐orbitocerebral mucormycosis
Authors: Bodenstein N. P. , Mcintosh W. A. , Vlantis A. C. , Urquhart A. C. 
Published: October 2006

AbstractMucormycosis is the most acutely fatal fungus infection of man (Ferry and Abedi).1 The most common clinical type of infection is rhino‐orbitocerebral mucormycosis. Prompt recognition of the clinical picture is essential if the appropriate urgent management is to be instituted without delay. The presence of black eschar in the region of the nasal passages, palate, midface, and orbit is the best‐recognized clinical sign alerting the clinician to the diagnosis. Black eschar is, however, a feature in only a minority of these patients at the time of presentation. This paper discusses other clinical signs, particularly orbital ischemia, which should suggest the diagnosis.The clinical presentation of orbital ischemia in mucormycosis includes proptosis, total external and internal ophthalmoplegia, and early blindless. A lax, nontender periorbital puffiness, which does not feel warm to the examiner's touch, is typical. Proptosis and chemosis, if present, are mild. These signs are compared with those of pyogenic orbital cellulitis, with which the condition might most easily be confused.
Acute Renal Failure Associated with Vancomycin- and Tobramycin-Laden Cement in Total Hip Arthroplasty
Authors: Patrick Benjamin N , Rivey Michael P , Allington Douglas R 
Published: October 2006

Objective: To describe 2 cases of acute renal failure (ARF) associated with the use of antibiotic-laden cement incorporated in total hip arthroplasties (THA). Case Summaries: An 82-year-old female received a right THA with antibiotic-laden cement spacers. She developed ARF 5 months following implantation, concurrent with an elevated serum tobramycin concentration of 5.5 μg/mL. After explantation of the prosthesis and spacers, serum creatinine and antibiotic concentrations decreased to within normal limits. A 79-year-old male received antibiotic-laden cement spacers in a revision of his right THA due to infection. ARF developed 1 1/2 months after the revision; a serum tobramycin concentration was 2.9 μg/mL Serum creatinine and antibiotic serum concentrations decreased to within normal limits with explantation. Discussion: More than 250 000 joint replacements are performed yearly in the US. A common complication is infection, which occurs in 1–2% of primary replacements and 3–4% of revisions of previously infected prostheses. Antibiotic-laden cement is used for prosthesis placement to prevent or treat infection, while minimizing systemic drug exposure. Both patients described here received antibiotic-laden spacers during THA and subsequently developed ARF in conjunction with elevated serum tobramycin concentrations. Use of the Naranjo probability scale and consideration of possible contributing factors suggest a probable association of the antibiotic-laden cement and the development of ARF in these patients. Conclusions: Antibiotic-laden cement with aminoglycosides and/or vancomycin has the potential for systemic toxicity and should be used according to guidelines and with increased vigilance and prudent monitoring in patients at increased risk for nephrotoxicity.
Methodology of Assessing Testing Variation for Volumetric Quantities in Hot Mix Asphalt Production
Authors: Pellinen T , Kuczek T 
Published: October 2006

Abstract
Increasingly, in road construction, pay incentives and disincentives are being related to both the average test results that are obtained during quality assurance testing as well as the variability associated with these values. As a result, state highway agencies must be fully aware of the expected variability that can be associated with each acceptance test since the results will not only be used for acceptance but may be used for pay adjustment also. In this study, a methodology was developed to assess the testing variability in hot-mix asphalt production. The study focused on determining allowable testing variations for the calculated volumetric quantities, including the air voids content and voids in mineral aggregate (VMA) determined from gyratory compacted specimens. A new standard of determining an allowable testing variation for VMA was developed. Furthermore, a test data analysis plan to extract the testing variation from the total measured variation for the hot-mix asphalt quality parameters was developed.
Unsafe tap water in households supplied from groundwater in the Salento Region of Southern Italy
Authors: Masciopinto Costantino , La Mantia Rosanna , Carducci Annalaura , Casini Beatrice , Calvario Agata , Jatta Edoardo 
Published: October 2006

Although the fractured aquifer of the Salento supplies over 80% of the drinking water requirements of the local population, its exposure to pollution has recently increased. In recent years, owing to the arid climate and droughts, the spreading of wastewater on soil for irrigation has become much more frequent. Consequently, hazardous and pathogenic microorganisms released with wastewater have been transported into the subsoil and have contaminated groundwater. An elaboration of epidemiological data has shown that the local population has the highest exposure to endemic gastroenteritis in Italy. In order to reduce human exposure to unsafe groundwater, the setback distance for drinking wells necessary to achieve the ‘natural disinfectionߣ criteria, has been determined experimentally at the Nardò aquifer (Salento region), supported by groundwater monitoring results and a mathematical transport model able to determine the apparent pathogenic microorganism pathways in fractures. The results also provided valuable inactivation constants of cultural indicators (coliforms, enterococci, Clostridium spores and somatic coliphages) and viruses in the wastewater that have been injected into the fractured aquifer since 1991. Furthermore, the efficacy of chlorine to remove viral indicators from water in a well 500 m from wastewater injection was tested. Hypochlorination reduces somatic coliphages and Clostridium spores in groundwaters but did not achieve complete inactivation in all tests. Complete disinfection of groundwater samples was possible only when there was an initial Clostridium spores count of ≤10 CFU 100 ml-1.
Polymicrogyria and deletion 22q11.2 syndrome: Window to the etiology of a common cortical malformation
Authors: Robin Nathaniel H. , Taylor Clare J. , McDonald‐McGinn Donna M. , Zackai Elaine H. , Bingham Peter , Collins Kevin J. , Earl Dawn , Gill Deepak , Granata Tiziana , Guerrini Renzo , Katz Naomi , Kimonis Virginia , Lin Jean‐Pierre , Lynch David R. , Mohammed Shehla N. , Massey Roger F. , McDonald Marie , Rogers R. Curtis , Splitt Miranda , Stevens Cathy A. , Tischkowitz Marc D. , Stoodley Neil , Leventer Richard J , Pilz Daniela T. , Dobyns William B. 
Published: October 2006

AbstractSeveral brain malformations have been described in rare patients with the deletion 22q11.2 syndrome (DEL22q11) including agenesis of the corpus callosum, pachygyria or polymicrogyria (PMG), cerebellar anomalies and meningomyelocele, with PMG reported most frequently. In view of our interest in the causes of PMG, we reviewed clinical data including brain‐imaging studies on 21 patients with PMG associated with deletion 22q11.2 and another 11 from the literature. We found that the cortical malformation consists of perisylvian PMG of variable severity and frequent asymmetry with a striking predisposition for the right hemisphere (P = 0.008). This and other observations suggest that the PMG may be a sequela of abnormal embryonic vascular development rather than a primary brain malformation. We also noted mild cerebellar hypoplasia or mega‐cisterna magna in 8 of 24 patients. Although this was not the focus of the present study, mild cerebellar anomalies are probably the most common brain malformation associated with DEL22q11. © 2006 Wiley‐Liss, Inc.
On Statistical Inference for the Random Set Generated Cox Process with Set‐marking
Authors: Penttinen Antti , Niemi Aki 
Published: October 2006

AbstractCox point process is a process class for hierarchical modelling of systems of non‐interacting points in ℝdunder environmental heterogeneity which is modelled through a random intensity function. In this work a class of Cox processes is suggested where the random intensity is generated by a random closed set. Such heterogeneity appears for example in forestry where silvicultural treatments like harvesting and site‐preparation create geometrical patterns for tree density variation in two different phases. In this paper the second order property, important both in data analysis and in the context of spatial sampling, is derived. The usefulness of the random set generated Cox process is highly increased, if for each point it is observed whether it is included in the random set or not. This additional information is easy and economical to obtain in many cases and is hence of practical value; it leads to marks for the points. The resulting random set marked Cox process is a marked point process where the marks are intensity‐dependent. The problem with set‐marking is that the marks are not a representative sample from the random set. This paper derives the second order property of the random set marked Cox process and suggests a practical estimation method for area fraction and covariance of the random set and for the point densities within and outside the random set. A simulated example and a forestry example are given. (© 2007 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
Synthesis and Characteristics of a Nonaggregating Tris(tetrathiafulvaleno)dodecadehydro[18]annulene
Authors: Andersson Asbjørn Sune , Kilså Kristine , Hassenkam Tue , Gisselbrecht Jean‐Paul , Boudon Corinne , Gross Maurice , Brøndsted Nielsen Mogens , Diederich François 
Published: October 2006

AbstractA new tris(tetrathiafulvaleno)dodecadehydro[18]annulene with six peripheral n‐hexyl substituents was prepared by oxidative Glaser–Hay cyclization of a corresponding diethynylated tetrathiafulvalene (TTF) precursor. The electronic properties of the neutral and oxidized species were studied by both UV/Vis absorption spectroscopy and electrochemistry. From these studies, it transpires that the strongly violet‐colored macrocycle does not aggregate in solution to any significant degree, which was confirmed by 1H NMR spectroscopy. This reluctance towards aggregation contrasts that observed for related TTF–annulenes containing other peripheral substitutents. Oxidation of the TTF–annulene occurs in two three‐electron steps as inferred from both the peak amplitudes and the spectroelectrochemical study. We find that the tris(TTF)‐fused dehydro[18]annulene is more difficult to oxidize (by +0.20 V) than the silyl‐protected diethynylated mono‐TTF precursor. In contrast, the first vertical ionization energy calculated at the B3 LYP/6–311+G(2d,p) level for the parent tris(TTF)‐fused dehydro[18]annulene devoid of peripheral hexyl substituents is in fact lower (by 0.44 eV). Moreover, the surface morphology of 1 d drop‐cast on a mica substrate was investigated by atomic force microscopy (AFM). Crystalline domains with slightly different orientations were observed. The thickness of individual layers seen in the crystalline domains and the thickness of a monolayer obtained from a very dilute solution were determined to 1.8–1.9 nm. This thickness corresponds to the diameter of the macrocycle and the layers seen in the film are apparently formed when the molecules stack in the horizontal direction relative to the substrate.
On the Paucity of Molecular Actinide Complexes with Unsupported Metal—Metal Bonds: A Comparative Investigation of the Electronic Structure and Metal—Metal Bonding in U2X6 (X: Cl, F, OH, NH2, CH3) Complexes and d‐Block Analogues
Authors: Cavigliasso German , Kaltsoyannis Nikolas 
Published: October 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
A New Oxide Ion Conductor: La3GaMo2O12.
Authors: Xia Tian , Li Jia‐Yan , Li Qin , Liu Xiang‐Dong , Meng Jian , Cao Xue‐Qiang 
Published: October 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Novel Nanocomposite Pt/RuO2×xH2O/Carbon Nanotube Catalysts for Direct Methanol Fuel Cells.
Authors: Cao Lin , Scheiba Frieder , Roth Christina , Schweiger Franz , Cremers Carsten , Stimming Ulrich , Fuess Hartmut , Chen Liquan , Zhu Wentao , Qiu Xinping 
Published: October 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
[Zn9Bi11]5‐: A Ligand‐Free Intermetalloid Cluster.
Authors: Goicoechea Jose M. , Sevov Slavi C. 
Published: October 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
CaCu3Ti4O12: Low‐Temperature Synthesis by Pyrolysis of an Organic Solution.
Authors: Liu Jianjun , Sui Yucheng , Duan Chun‐gang , Mei Wai‐Ning , Smith Robert W. , Hardy John R. 
Published: October 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Asymmetric Synthesis of Chiral Aldehydes by Conjugate Additions with Bifunctional Organocatalysis by Cinchona Alkaloids.
Authors: Wu Fanghui , Hong Ran , Khan Jihan , Liu Xiaofeng , Deng Li 
Published: October 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Enantioselective Synthesis of Bridged‐ or Fused‐Ring Bicyclic Ketones by a Catalytic Asymmetric Michael Addition Pathway.
Authors: Liu Duan , Hong Sungwoo , Corey E. J. 
Published: October 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
ortho‐Substituted Iodobenzenes as Novel Organocatalysts for Bromination of Alkenes.
Authors: Braddock D. Christopher , Cansell Gemma , Hermitage Stephen A. 
Published: October 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Synthesis of β‐Amino Ketones by Iridium(III)‐Catalyzed Direct‐Mannich Reaction.
Authors: Sueki Shunsuke , Igarashi Takeyuki , Nakajima Takayuki , Shimizu Isao 
Published: October 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Highly Z/E Stereoselective Approach to β‐Iodo Aza Morita—Baylis—Hillman Adducts.
Authors: Timmons Cody , Kattuboina Adiseshu , Banerjee Soham , Li Guigen 
Published: October 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Efficient Synthesis of 2‐Hydroxy‐3,4‐dienoates by Oxidation of Zirconiumallenyl Enolates with Dimethyldioxirane.
Authors: Hoffmann‐Roeder Anja , Krause Norbert 
Published: October 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Reaction of Electrophilic Allyl Halides with Amines: A Reinvestigation.
Authors: Mangelinckx Sven , Courtheyn Dirk , Verhe Roland , Van Speybroeck Veronique , Waroquier Michel , De Kimpe Norbert 
Published: October 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Toluene Dioxygenase Mediated Oxidation of Dibromobenzenes. Absolute Stereochemistry of New Metabolites and Synthesis of (‐)‐Conduritol E.
Authors: Finn Kevin J. , Collins Jonathan , Hudlicky Tomas 
Published: October 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
[6 + 4] Cycloaddition Reactions of Acceptor Thiophene Dioxides: The Synthesis of Substituted Azulenes.
Authors: Moiseev A. M. , Balenkova E. S. , Nenajdenko V. G. 
Published: October 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Simple and Convenient Synthesis of 3,5‐Bis‐(trifluoromethyl)benzylamine via Biomimetic 1,3‐Proton Shift Reaction.
Authors: Soloshonok Vadim A. , Yasumoto Manabu 
Published: October 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.