bluuebunny/crossref_metadata_2025_split huggingface dataset:
(198) Harnessing the Power of Tantric Practices: A Revolutionary Path to Enhanced Sexual Well-being and Transformation
Authors: Gentry M 
Published: March 2024

Abstract

Introduction
In recent years, the integration of holistic practices in the field of sexual medicine has gained significant attention. Among these practices, tantra stands out as a revolutionary approach that emphasizes mindfulness, energy cultivation, and connection. This article explores the profound impact of tantric practices on sexual well-being, drawing from a qualitative study involving six individuals who have experienced transformative changes in their lives through the practice of tantra. Their stories provide compelling evidence of the effectiveness of tantra in reducing anxiety, cultivating meaningful relationships, and enhancing overall sexual health.

Objective
This study aimed to assess the therapeutic benefits of tantra as an intervention for emotional regulation, specifically targeting symptoms of anxiety and depression while promoting relaxation and emotional connection. Through qualitative interviews with diverse tantra educators and practitioners, the study sought to understand the observed changes in their personal lives and relationships resulting from tantra mindfulness exercises.

Methods
This qualitative study employed interpretative phenomenological analysis (IPA) to explore the lived experiences of six tantra educators and practitioners. Interviews were conducted using a structured set of questions to ensure consistency. The interviews were recorded, transcribed, and analyzed to understand the changes observed in participants' lives and relationships as a result of practicing tantra mindfulness exercises. The study also referred to previous research on meditation and neuroplasticity to explore potential neurological changes associated with tantra practices.

Results
The findings of this qualitative study underscore the importance of embracing a multidimensional approach to sexual medicine. By integrating tantric philosophy and techniques into existing frameworks, professionals in the field can provide a holistic and sustainable approach to enhancing sexual well-being. Tantra offers a rich tapestry of practices that go beyond addressing physical symptoms, recognizing the interconnectedness of mind, body, and spirit in the pursuit of sexual health and fulfillment.

Conclusions
The conclusion summarizes the key research findings, emphasizing the transformative power of tantric practices in enhancing sexual well-being and fostering meaningful relationships. It highlights the potential of tantra to revolutionize the understanding and treatment of sexual concerns in the field of sexual medicine. The conclusion emphasizes the importance of a multidimensional approach to sexual medicine and encourages the incorporation of tantra for a more holistic approach to sexual well-being.

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(201) Impact of a Natural Mixture with the Black Chocolate, Chili, Spices in Order to Improve Male Sexual Function
Authors: Drasa K , Bylykbashi E 
Published: March 2024

Abstract

Introduction
The Aztec emperor Montezuma was reported to have drunk up to fifty cups a day of chocolate with chili and spices in it. He had to keep up his stamina to satisfy his many wives. It is thought that the ingredients of this mixture dilates the blood vessels and creates energy and focus.

Objective
Referring to Montezuma, the purpose of this study was to verify whether is enough to drink every night one cup as Montezuma, by ED men making a nice intercourse with their partners’ women, at least once a week.

Methods
101 patients with erectile dysfunction (ED) were enrolled between January 2014 and December 2017. Patients were classified as having mild (47), moderate (38) or severe (16) ED. Mean age was 50.3 years. A cup with black chocolate, chili and spices in it was administered by each patient, every night for 12 weeks. International Index of Erectile Function-Erectile Function (IIEF-EF) questionnaire was administered pre and post-treatment with all pts. Patients with concomitant medical diseases were excluded.

Results
IIEF-EF scores were significantly improved, with an increase of 79% in the mild ED group, an 83% improvement in the moderate ED group, and an improvement of 67% in the severe ED group compared with the baseline. The mean IIEF-EF scores for all patients showed significant improvement after 12 weeks of treatment (baseline 14.3±1.5 to 26.2 ±3.3; P= 0.01). Among other parameters penile rigidity and tumescence, showed significant improvement for all patients. No, significant side effects.

Conclusions
The black chocolate, chili and spices when mixed together, seem to work in synergy improving erectile function and in patients with ED, too. We reached the goal that nearly all patients performed a nice intercourse, once a week with their partners’ women. This study tell that what they quote about Emperor Montezuma are in fact true.

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(219) Lengthening Phalloplasty: Combined Technique of a Urologist and a Plastic Surgeon
Authors: Helmi A , Merdad T 
Published: March 2024

Abstract

Introduction
Lengthening phalloplasty is an operation that aims at increasing the length of the penile shaft. This procedure has been gaining popularity with different surgical techniques being described and possible suboptimal patient satisfaction rate that can be optimized. The most popular surgical method used for penile lengthening is release of the suspensory ligament. Our technique differs as it involves a combination of urological and plastic surgical steps to achieve the maximum length with the safest optimum outcome.

Objective
We are advocating the above unique modified surgical technique aiming to achieve the desired results with higher satisfaction rate.

Methods
A retrospective study including consecutive male patients presenting for penile lengthening over the last 6years. Patients underwent pre-operative andrology and psychological evaluation. All procedures were performed by the same urologist and plastic surgeon simultaneously. A successful surgical outcome is defined as: achieving a lengthening equal to or more than 2cm.

Results
A total of 82 married male patients were included. The age ranged from 26 to 40 years with a median of 33years. They had normal sexual activity with no psychiatric nor behavioural disturbance. The average pre-operative penile length was: 9.75 cm. the average additional penile lengthening achieved post-operatively was: 3.7 cm. with a range of 2.8 to 4.7 cm. There was no major complications or failure of the procedure observed. One patient suffered from partial wound dehiscence following return to sexual activity two week after surgery. Patients satisfaction with the outcome 6 months following surgery reached 31/32 with a single case of dissatisfaction owing to the residual scar (success rate of 97%).

Conclusions
We have concluded that using our multimodality technique that this type of phalloplasty is a safe procedure with 100% anatomical surgical success rate in achieving the desired length gain and overall patient satisfaction rate of 97% which has not been reported using the standard procedure.

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(245) Epididymo-Orchitis as the First Presentation of Brucellosis in an Endemic Area
Authors: El-Bahnasawy M , Alzahrani T , Alanazi M , Albalawi A 
Published: March 2024

Abstract

Introduction
Brucellosis, which is also called Mediterranean or Malta fever, is an endemic enzootic disease and can involve various organ systems. It is commonly endemic in the Mediterranean countries and the Middle East. Epididymo-orchitis is a focal form of human brucellosis. Brucella species cause granulomatous orchitis usually presenting as an acute or chronic unilateral swelling of the testis. Patients rarely present to the clinicians with acute scrotum due to Brucellosis Epididymo-Orchitis (BEO) as an initial finding.

Objective
Our aim is to estimate the prevalence of the BEO among the cases diagnosed with Epididymoorchitis in our hospital over the last four years.

Methods
Retrospective study from 2015–2018 involving all cases diagnosed with Epididymoorchitis in our hospital. A total of 92 cases of Epididymoorchitis were diagnosed during this period. These cases presented to ER complaining of severe unilateral scrotal pain, swelling, fever and sweating. Local examination showed swollen enlarged testis and epididymis with marked tenderness. Brucella serologic test for both B abortus and B melitensis were requested routinely for all cases of epididymo-orchitis. Scrotal Doppler ultrasonographic examination was requested at initial diagnosis and after 2 weeks to exclude abscess formation.

Results
Out of 92 cases, 8 were diagnosed to have brucellosis (8.7%). The median age of patients was 32 years (range, 18–41 years). All patients had positive history of consuming unpasteurized dairy products, which is a risk factor for brucellosis. The diagnosis of brucellosis was made via positive serological testing results (Brucella abortus and melitensis). One case showed testicular abscess formation. All cases were given combination of tetracyclin and rifampicin for 6–12 weeks. Two cases required prolonged hospital stay due to testicular abscess formation in one and development of Brucellosis spondylitis in the other. Gentamycin was added for one week in such cases.

Conclusions
In endemic regions for brucellosis, we have to consider it in the workup of all cases of epididiymo-orchitis. The diagnosis is easy by positive serology tests. Positive cases need special antibiotic combination protocol for longer time and close monitoring for development of local complications or other systemic brucellosis manifestations

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(257) Prostate w-point orgasm decrypted W
Authors: Wang Q 
Published: March 2024

Abstract

Introduction
Erectile dysfunction is a common disease, accounting for about 50% of adult males. No matter oral“Viagra” or surgical treatment, there are unsatisfactory, especially in the middle-aged and elderly men, there is no way, there are widowed and disabled groups. Only rely on ejaculation to get pleasure, will lose at least a third of the sex life. Prostate disease accounts for about 25 percent of the sexual dysfunction. Therefore, through the clinical observation of more than 50,000 patients, the author has improved the Prostate massage method and explored the effectiveness of diagnosis, treatment and rehabilitation not only for prostate diseases, but also for prostate diseases, a new model of male sexual pleasure-the w-spot massage technique-has also been found. 50%, 25%, 5-W.

Objective
To investigate a convenient and effective prostate W-spot orgasm. W.

Methods
200 cases were randomly selected from prostate disease recovered patients aged 40–60 years. They were divided into two groups, an observational one and a control one with a ratio of 1:1, the experimental group used the prostate W-spot massage (massage path resembles the letter W, hence the name) method, the control used the conventional prostate P massage method (P is the initials of Prostate, no specific positioning). After 1 or 2 courses of the treatment, the efficiency was investigated by questionnaires and interviews were conducted to compare the advantages and disadvantages (W and P were substituted throughout the text).200, 40–60, W (W)P (P Prostate) 1–2 (WP).

Results
91% effective rate for W and 73% effective rate for P.W 91% P 73%.

Conclusions
1. W is better than P. 2. A certain duration of W-spot massage can help excrete prostate fluid, prevent or relieve prostatitis, facilitate the recovery of prostate disorders and timely detect the prostate tumors. 3. The W-spot massage path coincides with the intersection of multiple meridian paths in Chinese medicine, especially the Ren and Du meridians which intersect here. Massage can smooth and refresh Blood and Qi according to Chinese medicine theory. 4. Prostate W-spot massage is another way of sexual pleasure for non-heterosexual interpersonal sexual relations men, gay men and those who have erectile dysfunction. It may also be conducive to the rehabilitation of certain erectile dysfunction. The prostate massage path can directly stimulate the ejaculatory ducts, producing an experience similar to that of an ejaculatory orgasm. However, its pleasurable physiological mechanism is unrelated to penile erection or stimulation, thus without an “off period” for prostate orgasm. 1. WP, 2.W, 3. 4.W, 5.W.

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(274) BMP2 Restores Erectile Dysfunction Through Neurovascular Regeneration and Fibrosis Reduction in Diabetic Mice
Authors: Kwon M , Choi M , Limanjaya A , Ock J , Yin G N , Jin S , Suh J , Chung D Y , Ryu J 
Published: March 2024

Abstract

Introduction
The odds of erectile dysfunction (ED) are thrice more prevalent in diabetes. Severe peripheral vascular and neural damage in diabetic patients responds poorly to PDE5 inhibitors. However, bone morphogenetic protein 2 (BMP2) is known to be involved in angiogenesis.

Objective
To assess the efficacy of BMP2 stimulating angiogenesis and augmenting nerve regeneration in a mouse model of diabetic-induced erectile dysfunction.

Methods
The induction of diabetes mellitus was done by streptozotocin (STZ, 50 mg/kg daily) administered intraperitoneally for five successive days to male C57BL/6 mice that were 8 weeks old. Eight weeks post inductions, animals were allocated to one of five groups: a control group, an STZ-induced diabetic mouse group receiving two intra-cavernous 20 μL PBS injections, or one of three BMP2 groups administered two injections of BMP2 protein (1μg, 5 μg, or 10 μg) diluted in 20 μL of PBS with three days interval between the first and second injection. The erectile functions were assessed two weeks after PBS or BMP2 protein injections by recording the ICP (intracavernous pressure) through cavernous nerve electrical stimulation. Angiogenic activities also nerve regenerating effects of BMP2 were determined in penile tissues, aorta, vena cava, the main pelvic ganglions, the dorsal roots, and from the primary cultured MCECs (mouse cavernous endothelial cells). Moreover, fibrosis-related factors protein expressions were evaluated by western blot.

Results
Erectile function recovery to 81% of the control value in diabetic mice was found with intra-cavernous BMP2 injection (5 μg/20 μL). Pericytes and also endothelial cells were extensively restored. It was confirmed that angiogenesis was promoted in the corpus cavernosum of diabetic mice treated with BMP2 through increased ex vivo sprouting of aortic rings, vena cava and penile tissues, and migration and tube formation of MCECs. BMP2 protein enhanced cell proliferation and reduced apoptosis in MCECs and penile tissues, and promoted neurite outgrowth in major pelvic ganglia and dorsal root ganglia under high-glucose conditions. Furthermore, BMP2 suppressed fibrosis by reducing MCEC fibronectin, collagen 1, and collagen 4 levels under high-glucose conditions.

Conclusions
BMP2 modulates neurovascular regeneration and inhibits fibrosis to revive the mice's erection function in diabetic conditions. Our findings propose that the BMP2 protein represents a novel and promising approach to treating diabetes-related erectile dysfunction (ED).

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(279) Quantitative Analyze of Psycho Diagnostic Data in the Diagnosis of Female Sexual Dysfunctions
Authors: Marshania Z , Chochnidze N , Injgia M 
Published: March 2024

Abstract

Introduction
Sexual activity is an important aspect of quality of life. It's a fact that mental disorders caused by sexual trauma in past, bullying, strict up bringing, stigmatization, low level of sexual education, playing important role in development of female sexual dysfunctions.

Objective
The aim of our study was to detect how effective is psycho diagnostic examination for timely diagnosis and adequately treatment of women with sexual dysfunctions.

Methods
In our research that was conducted from October 2022 to July 2023, at the Z.Marshania’s sexual medicine center participated 75 women with different sexual dysfunctions. The study was quantitative. We used a correlational analysis to assess the association between dependent and independent variables. Independent variables with a p-value &lt; 0.05 were taken as statistically significant with sexual dysfunction. To evaluate psychological characteristics, we took MMPI-1, SSTAI, and Beck Depression Questionnaire.

Results
All our patients had different sexual difficulties. 55% among 75 had psychological problems that were identified before the sexual dysfunction was discovered. The largest correlation (53%) was found between anxiety disorders and Female Orgasmic Disorder (FOD), as well as between depression and Female Hypoactive Sexual Desire Disorder (FHSDD) which was 34%. It is also worth emphasizing the style of life caused by strict traditional family education, due to which some of the patients had an inadequate perception of sexual life (63%).

Conclusions
The prevalence of sexual dysfunction among women with mental disorders is quite high, therefore, along with the treatment of sexual dysfunctions, it is important to properly evaluate the psychological state that can be performed effectively by psycho-diagnostic examination. Without it, the treatment of sexual dysfunctions among women will not be managed adequately.

Disclosure
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(286) Impact of Hormonal Treatment in Patients with Gender Dysphoria in the First Six Months of Treatment
Authors: Fernandes C , Nascimento S , Silva M , Pereira T , Gonçalves M 
Published: March 2024

Abstract

Introduction
Gender dysphoria (GD) is a mismatch of how we feel our identity, male or female, with the biological sex. This incongruity can lead to discomfort and suffering. Prejudice and discrimination may result in additional stress, with impact on quality of life (QV). Hormonal therapy (HT) is an important part of the treatment of patients with GD and can have an impact on sexual life and QV.

Objective
To assess the impact of HT on sexual desire and quality of life in patients with GD throughout the first 3 to 6 months of treatment.

Methods
Longitudinal study of quality of life (QL) and sexual desire (SD), before and 3 to 6 months after starting HT, using the WHO WHOQOL-BREF questionnaire, which assesses the physical, psychological, social and environmental domains, of DS (dyadic and solitary) through the Sexual Desire Inventory- 2 (SDI-2) questionnaire and obtaining sociodemographic, clinical and laboratory data on patients who came to our consultation with a diagnosis of GD.

Results
52 patients, with a mean age of 25.11 (18–56) years, completed the WHOQOL-BREF and SDI-2 questionnaires. 30 FtM (57.7%) and 22 MtF (42.3%). Almost half 49% (n= 26) had a comorbid psychiatric disorder. In FtM the average total testosterone (TT) increased from 0.320 ng/mL to 7.190 (+/- 2.340) ng/mL and in MtF the average TT increased from 6.86 ng/mL to 0.59 (+/- 41) ng/mL 3 to 6 months after starting HT, without serious side effects. FtM showed a significant increase in DS (p &lt; 0.01), both dyadic and solitary, while MtF showed a non-significant decrease in SD after the start of HT. There was a non-significant improvement in the physical, social relationships and environment domains and a significant improvement in the psychological domain (p &lt; 0.01). In the physical domain, FtM patients showed a significant improvement compared to MtF patients. 20% of patients reduced or stopped psychiatric medication. Despite the negative impact of HT on SD in MtF, there was an improvement in QoL and a reduction in the need for psychiatric medication. In FtM there was a significant improvement in the psychological and physical domain.

Conclusions
HT is safe, improves QoL and reduces the need for psychiatric medication in patients with GD. This improvement was significant in the psychological domain.

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An Automated Site-Specific Tip Preparation Method for Atom Probe Tomography Using Script-Controlled Focused Ion Beam/Scanning Electron Microscopy
Authors: Uzuhashi Jun , Ohkubo Tadakatsu , Hono Kazuhiro 
Published: March 2024

Abstract
The automation of the atom probe tomography (APT) tip preparation using a focused ion beam (FIB) with a scanning electron microscopy (SEM) dual-beam system will certainly contribute to systematic APT research with higher throughput and reliability. While our previous work established a method to prepare tips with a specified tip curvature and taper angle automatically, by using script-controlled FIB/SEM, the technique has been expanded to automated “site-specific” tip preparation in the current work. The improved procedure can automatically detect not only the tip shape but also the interface position in the tip; thus, the new function allows for control of the tip apex position. In other words, automated “site-specific” tip preparations are possible. The details of the automation procedure and some experimental demonstrations, that is, a Pt cap on Si, InGaN-based MQWs, and a p–n junction of GaAs, are presented.
A Time of Plague: Allegory, Seriality, and Historicity in Samuel R. Delany’s Return to Nevèrÿon
Authors: Jones Keith 
Published: March 2024

Abstract
Among the most prolific and consequential US writers, Samuel R. Delany has published novels and short stories, a magnificent autobiography, various memoirs of social commentary, extraordinary essays of literary theory and criticism, and numerous (written) interviews. However, it is his Nevèrÿon sword and sorcery series (1979-87) that he describes as his most ambitious narrative “experiment.” Occupying Delany for nearly a decade, Nevèrÿon’s singularity as a narrative experiment is not solely achieved in terms of its complex unfolding as a series, with each tale accumulating over four volumes into an astonishing ensemble of stories, images, and worlds. Beyond its unfolding and enfolding of tales and beyond its “play” at the “game” of sword and sorcery central to its fictional experiment is its commitment to the “paraliterary” construction of his text. Refusing the distinctions marked out by “literary” and “non-literary,” Delany uses a serial narrative platform to braid together philosophical discourses and genre elements into a theoretically complex textual ensemble that comes to include both the rupture of AIDS and of an AIDS-like epidemic into the ninth tale of the series, the novella The Tale of Plagues and Carnivals (1985). Referring to it as his “novel of crisis,” Delany weaves New York City and the fictional world of Kolhari into what he calls “a document of our times,” opening sword and sorcery to a baroque discursive and rhetorical flux historiographically aware of itself both as a marginal cultural form and as a document of lives at the margins of a world-historic plague.
A dragon’s flame of many colours: multiwavelength observations of flares from the active M binary CR Draconis
Authors: Jackman James A G , Shkolnik Evgenya L , Loyd R O Parke , Richey-Yowell Tyler , Llama Joe , Boyd David , Buchheim Bob , Iadevaia David , Martin Jack , Sims Forrest , Walker Gary , Wetmore John 
Published: March 2024

ABSTRACT
We present the results of a multiwavelength Professional–Amateur campaign to study the behaviour of flares from the active M1.5V star binary CR Draconis. CR Dra was observed with Transiting Exoplanet Survey Satellite (TESS) 20-s photometry, Swift near-ultraviolet (NUV) grism spectroscopy and with ground-based optical photometry and spectroscopy from a global collaboration of amateur astronomers. We detected 14 flares with TESS and Swift simultaneously, one of which also had simultaneous ground-based photometry and spectroscopy. We used the simultaneous two-colour optical and NUV observations to characterize the temperature evolution of the flare and test the accuracy of using optical data to predict NUV emission. We measured a peak temperature of $7100^{+150}_{-130}$ K for this flare, cooler than the typically assumed 9000 K blackbody model used by flare studies. We also found that the 9000 K blackbody overestimated the NUV flux for other flares in our sample, which we attributed to our Swift observations occurring during flare decays, highlighting the phase-dependence for the accuracy of flare models.