bluuebunny/crossref_metadata_2025_split huggingface dataset:
Experimental assessment of square-wave spatial spanwise forcing of a turbulent boundary layer
Authors: Knoop Max W. , Hartog Friso H. , Schrijer Ferdinand F. J. , van Campenhout Olaf W. G. , van Nesselrooij Michiel , van Oudheusden Bas W. 
Published: April 2024

Abstract
We present an experimental realisation of spatial spanwise forcing in a turbulent boundary layer flow, aimed at reducing the frictional drag. The forcing is achieved by a series of spanwise running belts, running in alternating spanwise direction, thereby generating a steady spatial square-wave forcing. Stereoscopic particle image velocimetry in the streamwise–wall-normal plane is used to investigate the impact of actuation on the flow in terms of turbulence statistics, drag performance characteristics, and spanwise velocity profiles, for a non-dimensional wavelength of $$\lambda _x^+ = 397$$

λ
x
+

=
397

. In line with reported numerical studies, we confirm that a significant flow control effect can be realised with this type of forcing. The scalar fields of the higher-order turbulence statistics show a strong attenuation of stresses and production of turbulence kinetic energy over the first belt already, followed by a more gradual decrease to a steady-state energy response over the second belt. The streamwise velocity in the near-wall region is reduced, indicative of a drag-reduced flow state. The profiles of the higher-order turbulence statistics are attenuated up to a wall-normal height of $$y^+ \approx 100$$

y
+

≈
100

, with a maximum streamwise stress reduction of 45% and a reduction of integral turbulence kinetic energy production of 39%, for a non-dimensional actuation amplitude of $$A^+ = 12.7$$

A
+

=
12.7

. An extension of the classical laminar Stokes layer theory is introduced, based on the linear superposition of Fourier modes, to describe the non-sinusoidal boundary condition that corresponds to the current case. The experimentally obtained spanwise velocity profiles show good agreement with this extended theoretical model. The drag reduction was estimated from a linear fit in the viscous sublayer in the range $$2 \le y^+\le 5$$

2
≤

y
+

≤
5

. The results are found to be in good qualitative agreement with the numerical implementations of Viotti et al. (Phys Fluids 21, 2009), matching the drag reduction trend with $$A^+$$

A
+

, and reaching a maximum of 20%.

Graphical abstract
A novel approach for improving open scene text translation with modified GAN
Authors: Cheema Yasmeen , Cheema Muhammad Nadeem , Nazir Anam , Khokhar Fahad Ahmed , Li Ping , Ahmed Ayaz 
Published: April 2024

Abstract
Text, as a vital tool for communication, is playing an imperative role in modern society. Precise high-level text translation systems are essential requirements in a wide range of real-world applications, such as robot navigation, industrial automation, image search, and instant translation. Regardless of improved research, a series of grand challenges may still become upon when translating text automatically in the real-world from open scene images. The difficulties mainly stem from multiplicity and inconsistency of text in open scenes, complication and obstruction of backgrounds, and deficient imaging conditions in uncontrolled circumstances for open scene images. The existing deep learning-based text translation systems do not eliminate the text for translation, and these applications just replace text on the reconstructed scene. To address the abovementioned shortcomings, this study proposed a novel approach for open scene text translation. Our system consists of five modules including scene text detection, text recognition, text elimination, text translation, and text insertion along with scene reconstruction. The novelty presented by our model lies in the idea of first eliminating the text from the open scene for accurate translation and then reconstructs the translated text on the image for its proper alignment. We specifically modified the existing generative adversarial network (GAN) architecture for improved performance of text elimination by introducing a novel strategy of text and scene concatenation to reduce the overall loss function. For this purpose, we created a synthetic dataset to train our GAN for text elimination module. Experiments on various standard text translation systems demonstrate that our integrated system is able to outperform state-of-the-art approaches in terms of result quality. We have achieved 90.87% of precision, 83.66% of recall, 87.116% of F1-score, and reduced both losses (

$$l_1$$

l
1

and

$$l_2$$

l
2

) up to 50% which is remarkable upon state-of-the-art translation systems.
Percutaneous intramedullary screw or rush pin fixation of unstable ankle fractures in patients with fragile soft tissue – retrospective study of 80 cases
Authors: Mortensen Simon Oksbjerre , Barckman Jeppe , Gundtoft Per Hviid 
Published: April 2024

Abstract
Introduction
The standard surgical procedure for unstable ankle fractures is fixation of the lateral malleolus with a plate and screws. This method has a high risk of complications, especially among patients with fragile skin conditions. The aim of this study was to estimate the re-operation rates and identify complications in patients with an unstable ankle fracture, surgically treated with an intramedullary screw or rush pin.

Materials and methods
We identified all patients who were surgically treated with either a 3.5-mm screw or rush pin at Aarhus University Hospital, Denmark, from 2012 to 2018. Major complications were re-operations within three months. We included 80 patients, of which 55 (69%) were treated with a 3.5-mm intramedullary screw and 25 (31%) with a rush pin. The majority of the study population was female (59) and the mean age was 75 (range 24 to 100) years. Of the 80 patients included, 41 patients had more than 2 comorbidities.

Results
Three patients underwent re-operation within three months due to either fracture displacement or hardware cutout. Radiographs obtained after six weeks showed that nine patients had loss of reduction. Additionally, four patients had superficial wound infections and six patients had delayed wound healing.

Conclusions
Intramedullary fixation of distal fibula fractures with either a screw or rush pin has low re-operation rates. However, the high proportion of patients with radiological loss of reduction is concerning.
Early range of motion results in good elbow function following conservative treatment of non-displaced radial head fractures
Authors: Egenolf Philipp , Ott Nadine , Babasiz Tamara , Hackl Michael , Mueller Lars-Peter , Wegmann Sebastian 
Published: April 2024

Abstract
Introduction
The aim of this study was to evaluate the range of motion (ROM), elbow function and predictors for good elbow function after conservative treatment of non-displaced radial head fractures.

Material and methods
All patients with non-displaced radial head fractures (displacement < 2 mm), that were diagnosed between January 1st 2017 and December 31st 2021 in a level I trauma center, were included in this retrospective case series and the charts were evaluated for ROM and elbow function. Elbow function was categorized as “good” or “bad” depending on the ROM measured defined by Morrey et al. Overall, 73 patients (33 male, 40 female) with an average age of 38 years (+/- 13 years) could be included.

Results
Conservative treatment had good clinical results for ROM and elbow function. After 6 weeks mean flexion was 131° (SD 13°), extension 8° (SD 7°), Pronation 83° (SD 11°) and Supination 83° (SD 13). Patients with a good elbow function after one week showed a good elbow function after completing the treatment.

Conclusions
A clinical assessment after one week should always be performed and the study showed that it is a good predictor for good elbow function. In cases of bad elbow function further controls should be considered.
Comparative study of postpartum sexual function: Second-degree tears versus episiotomy outcomes
Authors: Fernández-Fernández María José , de Medina-Moragas Alejandro Jesús 
Published: April 2024

AbstractPurposeThe effects of episiotomy and second-degree tears on postpartum sexual function are key areas of enquiry in women’s health research. Episiotomy and second-degree tears are common procedures and injuries that occur during childbirth. Understanding their impact on post-childbirth sexuality is crucial to women’s overall well-being. This study aimed to examine the relationship between episiotomy, second-degree tears, and post childbirth sexuality.MethodsA cross-sectional design was employed, including 83 women who gave birth to Cáceres in 2017. Participants were evaluated based on sociodemographic and sexual health factors.ResultsNo significant differences were found in dyspareunia or sexual function between women who underwent episiotomies and those with second-degree tears. However, women who underwent episiotomies waited longer before resuming sexual activity after childbirth. Factors such as age, number of previous births, employment status, educational level, and breastfeeding status affected the timing and frequency of postpartum sexual activity.ConclusionDyspareunia negatively affects various aspects of sexual function. When comparing episiotomy and second-degree tears, their impacts on postpartum sexual function were similar. However, episiotomy delays the resumption of sexual activity. Sociodemographic factors significantly influence postpartum sexual health. These findings highlight the importance of individualised interventions and support for new mothers during the postpartum period to address potential sexual health concerns.
Validation and recalibration of sex estimation methods using pubic nonmetric traits for the Chilean population
Authors: Rojas González Natalia , Obertová Zuzana , Franklin Daniel 
Published: April 2024

AbstractChile had a violent military coup (1973–1990) that resulted in 3,000 victims declared detained, missing or killed; many are still missing and unidentified. Currently, the Human Rights Unit of the Forensic Medical Service in Chile applies globally recognised forensic anthropological approaches, but many of these methods have not been validated in a Chilean sample. As current research has demonstrated population-specificity with extant methods, the present study aims to validate sex estimation methods in a Chilean population and thereafter establish population-specific equations. A sample of 265 os coxae of known age and sex of adult Chileans from the Santiago Subactual Osteology Collection were analysed. Visual assessment and scoring of the pelvic traits were performed in accordance with the Phenice (1969) and Klales et al. (2012) methods. The accuracy of Phenice (1969) in the Chilean sample was 96.98%, with a sex bias of 7.68%. Klales et al. (2012) achieved 87.17% accuracy with a sex bias of -15.39%. Although both methods showed acceptable classification accuracy, the associated sex bias values are unacceptable in forensic practice. Therefore, six univariate and eight multivariate predictive models were formulated for the Chilean population. The most accurate univariate model was the ventral arc at 96.6%, with a sex bias of 5.2%. Classification accuracy using all traits was 97.0%, with a sex bias of 7.7%. This study provides Chilean practitioners a population-specific morphoscopic standard with associated classification probabilities acceptable to accomplish legal admissibility requirements in human rights and criminal cases specific to the second half of the 20th century.
Effect of repeated post-resistance exercise cold or hot water immersion on in-season inflammatory responses in academy rugby players: a randomised controlled cross-over design
Authors: Horgan Barry G. , West Nicholas P. , Tee Nicolin , Halson Shona L. , Drinkwater Eric J. , Chapman Dale W. , Haff G. Gregory 
Published: April 2024

Abstract
Purpose
Uncertainty exists if post-resistance exercise hydrotherapy attenuates chronic inflammatory and hormone responses. The effects of repeated post-resistance exercise water immersion on inflammatory and hormone responses in athletes were investigated.

Methods
Male, academy Super Rugby players (n = 18, 19.9 ± 1.5 y, 1.85 ± 0.06 m, 98.3 ± 10.7 kg) participated in a 12-week programme divided into 3 $$\times$$
×
4-week blocks of post-resistance exercise water immersion (either, no immersion control [CON]; cold [CWI]; or hot [HWI] water immersion), utilising a randomised cross-over pre-post design. Fasted, morning blood measures were collected prior to commencement of first intervention block, and every fourth week thereafter. Linear mixed-effects models were used to analyse main (treatment, time) and interaction effects.

Results
Repeated CWI (p = 0.025, g = 0.05) and HWI (p < 0.001, g = 0.62) reduced creatine kinase (CK), compared to CON. HWI decreased (p = 0.013, g = 0.59) interleukin (IL)-1ra, compared to CON. HWI increased (p < 0.001–0.026, g = 0.06–0.17) growth factors (PDGF-BB, IGF-1), compared to CON and CWI. CWI increased (p = 0.004, g = 0.46) heat shock protein-72 (HSP-72), compared to HWI.

Conclusion
Post-resistance exercise CWI or HWI resulted in trivial and moderate reductions in CK, respectively, which may be partly due to hydrostatic effects of water immersion. Post-resistance exercise HWI moderately decreased IL-1ra, which may be associated with post-resistance exercise skeletal muscle inflammation influencing chronic resistance exercise adaptive responses. Following post-resistance exercise water immersion, CWI increased HSP-72 suggesting a thermoregulatory response indicating improved adaptive inflammatory responses to temperature changes, while HWI increased growth factors (PDGF-BB, IGF-1) indicating different systematic signalling pathway activation. Our data supports the continued use of post-resistance exercise water immersion recovery strategies of any temperature during in-season competition phases for improved inflammatory adaptive responses in athletes.
Unpacking associations among children’s spatial skills, mathematics, and arithmetic strategies: decomposition matters
Authors: Möhring Wenke , Moll Léonie , Szubielska Magdalena 
Published: April 2024

AbstractSeveral studies revealed links between mental rotation and mathematical tasks, but the intervening processes in this connection remain rather unexplored. Here, we aimed to investigate whether children’s mental rotation skills relate to their accuracy in solving arithmetic problems via their usage of decomposition strategies, thus probing one potential intervening process. To this end, we examined a sample of 6- to 8-year-olds (N = 183) with a chronometric mental rotation task, and asked children to solve several arithmetic problems while assessing their solution strategies. After each arithmetic problem, children were asked about their strategy to solve the respective arithmetic problem and these were classified as either counting, decomposition, or retrieval strategies. Analyses were controlled for age, sex, fluid and verbal reasoning. Results indicated that children’s response times and accuracy in the mental rotation task were best explained by linear functions of rotation angle, suggesting the usage of dynamic mental transformation strategies. A multiple mediation model revealed that children with higher mental rotation skills were more inclined to use higher-level mental strategies such as decomposition which in turn increased their accuracy of solving arithmetic problems. None of the other arithmetic strategies revealed significant indirect effects. These findings suggest that children with higher mental rotation skills may profit from visualizing and flexibly transforming numerical magnitudes, increasing the frequency of decomposition strategies. Overall, decomposition may play a unique role in the connection between children’s mental rotation and arithmetic skills, which is an essential information for planning future training and experimental studies.
Existence of energy-variational solutions to hyperbolic conservation laws
Authors: Eiter Thomas , Lasarzik Robert 
Published: April 2024

AbstractWe introduce the concept of energy-variational solutions for hyperbolic conservation laws. Intrinsically, these energy-variational solutions fulfill the weak-strong uniqueness principle and the semi-flow property, and the set of solutions is convex and weakly-star closed. The existence of energy-variational solutions is proven via a suitable time-discretization scheme under certain assumptions. This general result yields existence of energy-variational solutions to the magnetohydrodynamical equations for ideal incompressible fluids and to the Euler equations in both the incompressible and the compressible case. Moreover, we show that energy-variational solutions to the Euler equations coincide with dissipative weak solutions.
A comparison principle for semilinear Hamilton–Jacobi–Bellman equations in the Wasserstein space
Authors: Daudin Samuel , Seeger Benjamin 
Published: April 2024

AbstractThe goal of this paper is to prove a comparison principle for viscosity solutions of semilinear Hamilton–Jacobi equations in the space of probability measures. The method involves leveraging differentiability properties of the 2-Wasserstein distance in the doubling of variables argument, which is done by introducing a further entropy penalization that ensures that the relevant optima are achieved at positive, Lipschitz continuous densities with finite Fischer information. This allows to prove uniqueness and stability of viscosity solutions in the class of bounded Lipschitz continuous (with respect to the 1-Wasserstein distance) functions. The result does not appeal to a mean field control formulation of the equation, and, as such, applies to equations with nonconvex Hamiltonians and measure-dependent volatility. For convex Hamiltonians that derive from a potential, we prove that the value function associated with a suitable mean-field optimal control problem with nondegenerate idiosyncratic noise is indeed the unique viscosity solution.
On Multi-Component Gas Migration in Single-Phase Systems
Authors: Pitz Michael , Jacops Elke , Grunwald Norbert , Ziefle Gesa , Nagel Thomas 
Published: April 2024

AbstractThe present work deals with diffusion of gases in fully saturated porous media. We test and validate the gas transport mechanism of dissolution and diffusion, implemented in the TH2M process class in the open-source finite-element software OpenGeoSys. We discuss the importance of gas diffusion for the integrity of the multi-barrier system. Furthermore, we present a multi-component mass balance equation implementation in Python, which serves as a reference for the two-component TH2M implementation and allows for a discussion of multi-component gas diffusion in liquids. We verify and validate the numerical implementations as follows: First, we come up with a set of numerical benchmarks in which solutions obtained by the two-component TH2M and multi-component implementations are compared. Thus, we show under which conditions predictions made by the TH2M model can be used for multi-component gas systems. Finally, the work is validated using a through diffusion experiment performed at Belgium’s Nuclear Research Centre SCK CEN and a sensitivity analysis is conducted based on the featured experiment. The results of this work illustrate that predictions by both the two- and four-component models match the laboratory findings very well. Therefore, we conclude that also the two-component implementation can reflect the multi-component processes well under the given constraints such as full saturation.
Paradoxical effect of anti-inflammatory drugs on IL-6 mRNA expression in patients with PTSD during treatment
Authors: Rhein Cosima , Apelt Isabella , Werner Franziska , Schäflein Eva , Adler Werner , Reichel Martin , Schug Caterina , Morawa Eva , Erim Yesim 
Published: April 2024

AbstractThe pathophysiology of posttraumatic stress disorder (PTSD) is associated with the activation of the innate immune system, including cytokines like interleukin 6 (IL-6). However, the role of IL-6 in the etiology and treatment of PTSD still remains elusive. We conducted a prospective controlled trial to investigate the development of IL-6 during psychosomatic treatment in individuals with PTSD in comparison with individuals without PTSD. We assessed IL-6 mRNA expression before and after 2 months of psychosomatic treatment in individuals with and without PTSD. Severities of PTSD and depressive symptoms were assessed in parallel. Linear mixed regression was applied for statistical analysis, including the factors diagnosis PTSD and pre–post treatment after subgrouping for intake of anti-inflammatory drugs. The development of IL-6 mRNA expression during treatment was affected by the use of anti-inflammatory drugs. In the subgroup without intake of anti-inflammatory drugs, no significant statistical treatment effect in individuals with and without PTSD emerged. In the subgroup of individuals taking anti-inflammatory drugs, a significant interaction effect of the factors pre–post treatment and diagnosis PTSD was observed. Whereas IL-6 mRNA expression in individuals without PTSD decreased according to amelioration of symptoms, IL-6 mRNA expression in individuals with PTSD increased significantly during treatment, in opposite direction to symptom severity. Anti-inflammatory drugs might affect IL-6 mRNA expression in individuals with PTSD in a paradoxical way. This study offers a further piece of evidence that IL-6 could be involved in the pathophysiology of PTSD and PTSD-specific immunologic molecular mechanisms.
Advanced therapies in Parkinson’s disease: an individualized approach to their indication
Authors: Schröter Nils , Sajonz Bastian E. A. , Jost Wolfgang H. , Rijntjes Michel , Coenen Volker A. , Groppa Sergiu 
Published: April 2024

AbstractDevice aided therapies (DAT) comprising the intrajejunal administration of levodopa/carbidopa intestinal gel (LCIG) and levodopa/carbidopa/entacapone intestinal gel (LECIG), the continuous subcutaneous application of foslevodopa/foscarbidopa or apomorphine infusion (CSAI) and deep brain stimulation (DBS) are used to treat Parkinson’s disease with insufficient symptom alleviation under intensified pharmacotherapy. These DAT significantly differ in their efficacy profiles, indication, invasiveness, contraindications, and potential side effects. Usually, the evaluation of all these procedures is conducted simultaneously at the same point in time. However, as disease progression and symptom burden is extremely heterogeneous, clinical experience shows that patients reach the individual milestones for a certain therapy at different points in their disease course. Therefore, advocating for an individualized therapy evaluation for each DAT, requiring an ongoing evaluation. This necessitates that, during each consultation, the current symptomatology should be analyzed, and the potential suitability for a DAT be assessed. This work represents a critical interdisciplinary appraisal of these therapies in terms of their individual profiles and compares these DAT regarding contraindications, periprocedural considerations as well as their efficacy regarding motor- and non-motor deficits, supporting a personalized approach.