bluuebunny/crossref_metadata_2025_split huggingface dataset:
Ultrastructural study of tissues surrounding replanted teeth and dental implants
Authors: Shioya Kazuhiro , Sawada Takashi , Miake Yasuo , Inoue Sadayuki , Yanagisawa Takaaki 
Published: February 2009

AbstractObjectives: The aim of this study was to describe the ultrastructure of the dentogingival border at replanted teeth and implants.Material and methods: Wistar rats (8 weeks old) were divided into groups for replantation and implantation experiments. In the former, the upper right first molars were extracted and then immediately replanted. In the latter, pure titanium implants were used. All tissues were fixed, demineralized and embedded in epoxy resin for ultrastructural observations.Results: One week after replantation, the junctional epithelium was lost, and the oral sulcular epithelium covered the enamel surface. The amount of the epithelium increased in 2 weeks, and resembled the junctional epithelium, and the internal basal lamina and hemidesmosomes were formed in 4 weeks. One week after implantation, peri‐implant epithelium was formed, and in 2 and 4 weeks, this epithelium with aggregated connective tissue cells were observed. In 8 weeks, the peri‐implant epithelium receded, and aligned special cells with surrounding elongated fibroblasts and bundles of collagen fibers appeared to seal the implant interface.Conclusion: In replantation of the tooth, the internal basal lamina remained at the surface of the enamel of the replanted tooth, which is likely to be related to regeneration of the junctional epithelium and the attachment apparatus at the epithelium–tooth interface. Following implantation, a layer of cells with characteristics of connective tissue cells, but no junctional epithelium and attachment apparatus, was formed to seal the site of the implant.
Prospective clinical evaluation of 1920 Morse taper connection implants: results after 4 years of functional loading
Authors: Mangano C. , Mangano F. , Piattelli A. , Iezzi G. , Mangano A. , La Colla L. 
Published: February 2009

AbstractPurpose: This study evaluated the survival rate and the clinical, radiographic and prosthetic success of 1920 Morse taper connection implants.Material and methods: One thousand nine hundred and twenty Morse taper connection implants were inserted in 689 consecutive patients, from January 2003 until December 2006. Implants were clinically and radiographically evaluated at 12, 24, 36 and 48 months after insertion (mean follow‐up per implant: 25.42 months). Modified plaque index (mPI), modified sulcus bleeding index, probing depth (PD) and the distance between implant shoulder and first crestal bone–implant contact (DIB) were measured in mm. Success criteria included the absence of suppuration and clinically detectable implant mobility, PD<5 mm, DIB<1.5 mm after 12 months of functional loading and not exceeding 0.2 mm for each following year, the absence of recurrent prosthetic complications at the implant–abutment interface. Prosthetic restorations were fixed partial prostheses (364 units), single crowns (SCs: 307 units), fixed full‐arch prostheses (53 units) and overdentures (67 units).Results: The overall cumulative implant survival rate was 97.56% (96.12% in the maxilla and 98.91% in the mandible). The cumulative implant success rate was 96.61% (95.25% in the maxilla and 98.64% in the mandible). Only a few prosthetic complications were reported (0.65% of loosening at implant–abutment interface in SCs).Conclusion: The use of Morse taper connection implants represents a successful procedure for the rehabilitation of partially and completely edentulous arches. The absence of an implant–abutment interface (microgap) is associated with minimal crestal bone loss. The high mechanical stability significantly reduces prosthetic complications.
A molecular analysis of biclonal follicular lymphoma: further evidence for bone marrow origin and clonal selection
Authors: Nakamura Yuichi , Sato Yasutaka , Yoshida Katsuhiko , Kakegawa Emi , Ito Yoshihiro , Seyama Atsushi , Kayano Hidekazu , Bessho Masami 
Published: February 2009

AbstractWe report a follicular lymphoma (FL) case presenting the coexistence of two tumor cell subpopulations in lymph node (LN) and bone marrow (BM), which exhibited an inverse pattern of immunoglobulin light (IgL) chain gene rearrangement and expression: Igκ−λ+ in LN and Igκ+λ− in BM. These tumor clones shared an identical BCL2‐IgH recombination, accompanying t(14;18)(q32;q21) translocation, and an identical variable, diversity and joining segments joining with clone‐specific VH somatic hypermutations on the untranslocated IgH allele. Our study provides further evidence that FL clones, originating from common progenitor cells, can be developed independently at different sites and with different IgL expression after immune selection.
Family‐based association analysis of S100A8 genetic polymorphisms with aggressive periodontitis
Authors: Ren X. Y. , Xu L. , Meng H. X. , Zhao H. S. , Lu R. F. , Chen Z. B. , Feng X. H. , Shi D. , Zhang L. , Tian Y. 
Published: February 2009

Background and Objective:  It is known that S100A8, a member of the S100 calcium‐binding protein family, is associated with inflammatory diseases, including periodontitis. Our previous population‐based study found an association between two polymorphisms, rs3795391 (A > G) and rs3806232 (A > G), in the upstream region of the S100A8 gene and aggressive periodontitis (AgP) in Chinese people. Based on those results, this investigation set out to analyze and corroborate whether the association also exists within families.Material and Methods:  Two hundred and four subjects from 73 nuclear families were recruited. All probands and their relatives were diagnosed according to the 1999 classification of periodontal diseases. Anticoagulated peripheral blood samples were collected from all the subjects, and DNA was extracted. The two single nucleotide polymorphisms (SNPs; rs3795391 and rs3806232) were detected and analyzed by standard polymerase chain reaction–restriction fragment length polymorphism (PCR‐RFLP) assay. Analysis of genotype/allele was performed by Family‐Based Association Test (FBAT) software (http://www.biostat.harvard.edu/~fbat/default.html).Results:  There was a statistically significant association of the SNP rs3795391 with AgP in the additive genetic model (χ2 = 3.9836, d.f. = 1, p = 0.0459). Allele A showed significantly preferential transmission to the AgP affected individuals (Z = 1.996, p = 0.0459). The other SNP, rs3806232, showed no significant results in all models.Conclusions:  This family‐based association study supports the previous findings that SNP rs3795391 (A > G) of the S100A8 gene might contribute to AgP susceptibility. This is, to our knowledge, the first investigation about AgP using FBAT in genetic analysis.
Effect of dietary omega‐3 polyunsaturated fatty acids on experimental periodontitis in the mouse
Authors: Bendyk A. , Marino V. , Zilm P. S. , Howe P. , Bartold P. M. 
Published: February 2009

Background and Objective:  Periodontitis is an infective disease caused predominantly by gram‐negative anerobes. The host inflammatory response to these bacteria causes alveolar bone loss, which characterizes periodontitis. Omega‐3 polyunsaturated fatty acids have recognized anti‐inflammatory effects; their oxygenated derivatives are key mediators in reducing inflammation. In this study we tested the hypothesis that dietary supplementation with tuna fish oil rich in the n‐3 polyunsaturated fatty acid, docosahexaenoic acid, would reduce alveolar bone loss in mice inoculated with periodontopathic bacteria.Material and Methods:  Adult mice were fed experimental diets containing either 10% tuna oil or Sunola oil for 57 d. After 14 d, 35 mice on each diet were inoculated orally with Porphyromonas gingivalis, with a mixture of P. gingivalis and Fusobacterium nucleatum, with carboxymethylcellulose or remained untreated. The mice were killed, and soft tissue biopsies from the oral cavity of treated mice were used to determine the polyunsaturated fatty acid concentrations. The maxilla was removed, stained and digitally imaged to assess bone loss around the upper molars.Results:  n‐3 polyunsaturated fatty acid levels were significantly higher in oral soft tissues of mice fed tuna oil compared with the control group. Mice fed tuna oil and inoculated with P. gingivalis or with the combination of F. nucleatum and P. gingivalis exhibited 72% and 54% less alveolar bone loss respectively, compared with the treatment control group.Conclusion:  Alveolar bone loss was inversely related to n‐3 polyunsaturated fatty acid tissue levels. In conclusion, fish oil dietary supplementation may have potential benefits as a host modulatory agent in the prevention and/or adjunctive management of periodontitis.
Stipa tenacissima as a nurse plant of the endemic species Haplophyllum bastetanum near Granada, SE Spain
Authors: Navarro F.B. , Lorite J. , Fernández‐Ondoño E. , Ripoll M.A. , Jiménez M.N. 
Published: February 2009

Question: What is the role of Stipa tenacissima as a nurse plant of the rare and threatened endemic species Haplophyllum bastetanum?Location: Semi‐arid steppe of the Guadix‐Baza basin (SE Spain).Methods: In the two H. bastetanum populations known, we (1) estimated the number of individuals and (2) analysed the influence of the factors ‘site’ (S1 = Hernán Valle, S2 = Alicún), ‘microhabitat’ (inside and below the canopy of the S. tenacissima tussocks vs. open areas), ‘life stage’ (vegetative, reproductive), ‘aspect’ (N, S, E, W, flat) and ‘damage’ (yes or no), in relation to the distribution of individuals and to the height, number of flowers, number of capsules, and edaphic variables.Results: The total number of individuals was estimated at 3135. S. tenacissima was found to have a positive and significant effect on the distribution of H. bastetanum, more pronounced in the sample taken at S2 than S1, where 83.8% of the plants were growing in association with S. tenacissima. Similarly, there were more H. bastetanum individuals that became reproductive inside S. tenacissima tussocks than in the open areas, and H. bastetanum individuals had a greater production of flowers and fruits, especially in the sample taken at S1. Organic carbon, nitrogen, and carbon:nitrogen ratio were related to the height and number of flowers and capsules of the plants.Conclusion: Although new patches were established, with a larger number of individuals, H. bastetanum continues to be Critically Endangered (CR). The results support the hypothesis of the facilitation effect of S. tenacissima on this rare, endemic species. Facilitation of species of interest in conservation is an aspect that has not previously been clearly reported. We propound this important process as a valuable tool for rehabilitation of populations of threatened plant species in conservation biology projects.
The effects of habitat edges and trampling on understorey vegetation in urban forests in Helsinki, Finland
Authors: Hamberg Leena , Lehvävirta Susanna , Malmivaara‐Lämsä Minna  , Rita Hannu , Kotze D. Johan 
Published: February 2009

AbstractQuestion:How do habitat edges and trampling affect mesic (Myrtillustype) understorey vegetation in fragmented urban forests, and what are the relative strengths and spatial extent of these effects?Location:The city of Helsinki, southern Finland.Methods:Vegetation sample plots were placed at different distances from the forest edge. At each distance we selected plots on, next to and away from paths of different levels of wear, and the covers and frequencies of plant species were sampled. We used generalized linear mixed models and ordination techniques to test our hypotheses.Results:The effect of the edge penetrated up to 50 m into the forest interior. Only light effects of trampling were found in seemingly untrampled areas, in addition to the direct effects of trampling on the paths. Both trampling and edge effects changed the forest understorey species composition. Trampling changed plant species composition locally on paths, and provided opportunities for new species to establish in previously unbroken forest vegetation. Urban forest edges were characterised by species better adapted to sunny, warm and dry conditions. These species, such as grasses, replaced more sensitive forest species, such as dwarf shrubs and mosses. We observed a large number of light demanding deciduous trees at the edges, which may be one of the factors increasing soil fertility and consequently promoting the high abundance of fast growing species, such as grasses and herbs related to more fertile site types.Conclusions:We recommend that urban forest fragments left within urban development should be at least 2–3 ha in size and that the shape of the patch and the number of potential recreational users should be taken into account when preserving true forest understorey vegetation from the effects of edges and trampling.
The transition from invasive species control to native species promotion and its dependence on seed density thresholds
Authors: Reinhardt Adams Carrie , Galatowitsch Susan M. 
Published: February 2009

AbstractQuestion: Does the seed density of invasive species affect establishment by native species in a bare ground context (following invasive species control efforts), and is it possible to promote transition to a native species dominated state by manipulating sowing density of the native community?Location: Experimental wetland basin in Chanhassen, Minnesota, USA.Methods: A mesocosm experiment investigated the influence of Phalaris arundinacea (invasive species) propagule pressure on establishment of native wet meadow species in the context of a newly restored wetland. Mesocosms were sown with P. arundinacea (0, 10, 50, 100, or 500 seeds/m2) and a mix of native species (3000 or 15000 seeds/m2).Results: When planted at densities > 100 seeds/m2, P. arundinacea increased suppression of native species. Also, high native seed density suppressed P. arundinacea biomass production. This effect was more pronounced when P. arundinacea seed density was high (> 100 seeds/m2), but high native seed density (15000 seeds/m2) did not suppress recruitment of P. arundinacea from seed.Conclusions: The transition from post‐control bare ground (a common result of efforts to control invasive species) to native species establishment depends on both native species and invader seed density. These results suggest that a threshold of P. arundinacea propagule pressure exists, beyond which transition to a native community is less likely without management intervention. P. arundinacea can establish in the presence of a newly developing native plant community, even at very low densities of P. arundinacea seed. Invader control (following initial site clearing efforts) is essential to native species establishment.
Vegetation recovery after fuel management in Mediterranean shrublands
Authors: Baeza M.J. , Vallejo V.R. 
Published: February 2009

Question: What is the effect of fuel management practices in the recovery capacity of seeder‐dominated shrublands?Location: Ulex parviflorus shrubland localities in Mediterranean regions of eastern Spain.Methods: We applied prescribed burning and brush‐chipping as fuel management techniques in three young and three mature shrublands, and evaluated the effects in the following four years.Results: Canopy opening by the treatments allowed increasing species richness through the four years of secondary succession. The treatments produced a change in community structure and dominant species, from the woody seeder Ulex parviflorus to the resprouter grass Brachypodium retusum. Vegetation response was conditioned by both shrubland developmental stage and treatment applied. Burning resulted in more severe modification of the ecosystem, increasing bare soil cover. Four years after fuel management in different aged Mediterranean gorse shrublands, vegetation response followed a similar pattern with the exception of the young, brush‐chipped shrublands. The treatments applied for controlling Ulex parviflorus were seen to be very effective, with the exception of brush‐chipping in young shrublands.Conclusions: Selective brush‐chipping in middle‐aged or mature gorse shrublands would combine a drastic reduction in fire hazard with ecosystem conservation and regeneration.
Interalar Distance to Estimate the Combined Width of the Six Maxillary Anterior Teeth in Oral Rehabilitation Treatment
Authors: GOMES VANDERLEI LUIZ , GONÇALVES LUIZ CARLOS , COSTA MARCIO MAGNO , DE LIMA LUCAS BARBARA 
Published: February 2009

ABSTRACTStatement of the Problem:  The face's architecture of dentate subjects has been studied to find a reliable guide for the selection of artificial anterior teeth. However, there is no consensus of data regarding a reference to estimate the width of artificial teeth.Purpose:  The purpose of this study was to analyze whether there is a consistent relationship between the interalar distance (IAD) and the combined mesiodistal width of the six maxillary anterior teeth.Methods:  Standardized digital photographs of 81 dentate Brazilian subjects were included in the sample. They were 37 men and 44 women (age 17 to 33). Through image processing software, the IAD and the distance between the tips of the maxillary canines were measured when viewed from the frontal aspect. Accurate casts were made to quantify the distance between the distal surfaces of the maxillary canines on a curve, by use of a flexible millimeter ruler. Nonparametric statistics were performed to analyze the results (p < 0.05).Results:  The IAD when compared with the width of the six maxillary anterior teeth, on a straight line and on a curve, presented a ratio of 0.914 and of 1.305, respectively. The Wilcoxon test showed no significant difference between the calculated width values and the mesiodistal width measured on a curve and on a straight line (p = 0.986).Conclusion:  The IAD, when increased by 31% of its value, can suggest the circumferential distance of the six maxillary anterior teeth.CLINICAL SIGNIFICANCEThe width of the nose, when measured in digital photographs, can be utilized as a reliable guide for the selection of the maxillary anterior teeth width. It can improve the esthetic result of the oral rehabilitation treatment for the edentulous patient by offering a natural dentofacial relation.
Concurrence Between the Maxillary Midline and Bisector to the Interpupillary Line
Authors: ESKELSEN EVANIA , FERNANDES CAMILA BORGES , PELOGIA FERNANDA , CUNHA LEONARDO GONÇALVES , PALLOS DÉBORA , NEISSER MAXIMILIANO PIERO , LIPORONI PRISCILA CHRISTIANE SUZY 
Published: February 2009

ABSTRACTPurpose:  Symmetry is one of the factors that contributes to facial harmony, and in oral rehabilitation it determines the success of esthetic treatment. Therefore, the aim of the present study was to analyze the axial symmetry between the bipupillar midline and maxillary central incisors midline of 102 dental students (both genders) distributed across five Brazilian dental schools.Materials and Methods:  Students with no teeth missing and who had never been subjected to any dental treatment were selected. Photographs were taken with a Dental Eye III camera with a 100‐mm macro objective and ratio of 1 : 10 from natural size, recorded on an Ektachrome ASA/ISO 100 film. The images were developed and applied to Microsoft Office Power Point 2007 software. The results were analyzed by analysis of variance and Student's t‐test (α = 0.05).Results:  There was no significant correlation between bipupillar midline and the maxillary dental midline, irrespective of gender.Conclusion:  No significant coincidence was observed between the interpupillary and dental midline. However, the interpupillar distance and its relationship with other anatomic structures may be used as a reference in treatment, but measurements must be assessed individually.CLINICAL SIGNIFICANCEAnatomic measurements and facial proportions can be helpful during the planning of esthetic oral rehabilitation.
Predictors of Response to Sildenafil Citrate Following Radiation Therapy for Prostate Cancer
Authors: Teloken Patrick E. , Parker Marilyn , Mohideen Najeeb , Mulhall John P. 
Published: February 2009

ABSTRACT

Introduction
Phosphodiesterase type 5 inhibitor (PDE5) use is a treatment strategy for prostate cancer patients with post-radiation therapy (RT) erectile dysfunction (ED).

Aim
To define the predictors of sildenafil response in men treated with RT for prostate cancer.

Main Outcome Measures
International Index of Erectile Function (IIEF).

Methods
Patients were enrolled prospectively if they met the following criteria: (i) either a three-dimensional conformal external beam (EBRT) or brachytherapy (BT) with or without androgen deprivation (AD) for prostate cancer; (ii) self-reported ability to have sexual intercourse prior to RT; (iii) experienced onset of ED following RT; (iv) candidates for sildenafil citrate use; (v) followed-up periodically; and (vi) completed the IIEF at least 12 months after RT. Failure to respond to sildenafil was defined as IIEF-erectile function (EF) domain score of &lt;22.

Results
One hundred fifty-two patients met all the criteria: 110 in the EBRT group and 42 in the BT group. Mean age was 62 years. The mean follow-up was 38 months. Mean radiation dose for EBRT was 78 Gy and for BT was 101 Gy. Thirty-five patients received AD, 25% of EBRT, and 62% of BT patients. Sixty-one percent of the patients receiving AD had exposure only pre-RT, whereas 39% had pre- and post-RT AD exposure. The mean duration of AD was 4.6 months. Post-RT IIEF-EF domain score at &gt;24 months was 17. Successful response to sildenafil occurred in 68% of men at 12 months after RT, 50% at 24 months, and 36% at 36 months. On multivariable analysis, predictors of failure to respond to sildenafil were: older age, longer time after RT, AD &gt; 4 months duration, and RT dose &gt; 85 Gy. Modality of radiation delivery was not predictive of sildenafil failure.

Conclusions
A steady decrease in sildenafil response was seen with increasing duration after RT. Several factors were predictive of sildenafil failure.
Concept Analysis of Loneliness With Implications for Nursing Diagnosis
Authors: ElSadr Cheryl Bombassei , Noureddine Samar , Kelley Jane 
Published: February 2009

PURPOSE.  This study aims to explore the concept of loneliness using Walker and Avant's concept analysis framework. In addition, the overlap and potential confusion of the factors related to the nursing diagnoses Social Isolation and Risk for Loneliness were noted and discussed.DATA SOURCES.  A literature review was conducted by searching Google, CINAHL, PsychINFO, and MEDLINE databases using the keywords “loneliness,”“concept analysis,” and “loneliness concept analysis” in the title. Only those sources that directly addressed loneliness were used (27). DATA SYNTHESIS.  Dictionary definitions, various uses, and critical attributes were identified; model, borderline, related, and contrary cases were developed; and antecedents, consequences, and empirical referents were determined. Data were evaluated and summarized to reach conclusions and recommendations. CONCLUSIONS.  The authors concluded with a recommendation that Loneliness replace Social Isolation as the primary nursing diagnosis in the NANDA International taxonomy.