bluuebunny/crossref_metadata_2025_split huggingface dataset:
Parental Love and Filial Equality
Authors: Floris Giacomo , Spotorno Riccardo 
Published: April 2024

AbstractIt is widely accepted that parents have a fundamental moral obligation to consider and treat their children as each other’s equals. Yet the question of what grounds the equality of status among children in the eyes of their parents has so far been largely neglected in the literature on the philosophy of childhood and the ethics of parenthood. This paper fills this gap by developing a novel theory of the basis of filial equality: it argues that parents ought to consider and treat their children as equals by virtue of loving them. Parental love is the basis of filial equality.
Moderatism and Truth
Authors: Echeverri Santiago 
Published: April 2024

AbstractAccording to moderatism, perceptual justification requires that one independently takes for granted propositional hinges. This view faces the truth problem: to offer an account of truth for hinges that is not threatened by skepticism. Annalisa Coliva has tried to solve the truth problem by developing a new form of alethic pluralism. I argue that the resulting view cannot offer a coherent characterization of “skeptical switch scenarios” while providing an effective anti-skeptical strategy. In a more positive vein, I defend an approach that combines a correspondence conception of truth with epistemological disjunctivism.
What PIs want when hiring a clinical research coordinator
Authors: Fisher Elaine , Thomas Rebecca , Choi Ikseon , McCauley Linda 
Published: April 2024

Abstract

Introduction:
Clinical research coordinators (CRCs) play a key role in supporting the translational research enterprise, with responsibilities encompassing tasks related to the design, implementation, and evaluation of clinical research trials. While the literature explores CRC competencies, job satisfaction, and retention, little attention has been given to the role of the PI working with Human Resources (HR) in the CRC hiring and onboarding processes. We investigated the priorities, decision-making processes, and satisfaction levels of principal investigators (PIs) and hiring managers in CRC hiring.

Methods:
An online survey consisting of open-ended and fixed-choice questions to gather information on desired CRC qualifications and competencies, factors influencing hiring decisions, and overall satisfaction with selected candidates was administered. The survey utilized a Task/Competency Checklist developed from job descriptions and the literature. Respondents were asked to rank the importance of factors such as CRC skill set, years of experience, educational background, and budget constraints.

Results:
Results indicated that the skill set of the applicant was the most frequently cited factor influencing the hiring decision, followed by years of experience. Education and budget constraints were of lesser importance. Most respondents reported a satisfaction rating of 50% or greater with their new hires, although some participants expressed challenges related to institutional training requirements, the performance of entry-level CRCs, and the qualifications of experienced candidates.

Conclusion:
The hiring cycle involves HR-PI collaboration for a clear job description, effective onboarding processes, and accessible professional development opportunities to enhance PI and employee satisfaction and CRC retention.
AAV-mediated gene therapies for glaucoma and uveitis: are we there yet?
Authors: Castro Brenda , Steel Jason C. , Layton Christopher J. 
Published: April 2024

Abstract
Glaucoma and uveitis are non-vascular ocular diseases which are among the leading causes of blindness and visual loss. These conditions have distinct characteristics and mechanisms but share a multifactorial and complex nature, making their management challenging and burdensome for patients and clinicians. Furthermore, the lack of symptoms in the early stages of glaucoma and the diverse aetiology of uveitis hinder timely and accurate diagnoses, which are a cause of poor visual outcomes under both conditions. Although current treatment is effective in most cases, it is often associated with low patient adherence and adverse events, which directly impact the overall therapeutic success. Therefore, long-lasting alternatives with improved safety and efficacy are needed. Gene therapy, particularly utilising adeno-associated virus (AAV) vectors, has emerged as a promising approach to address unmet needs in these diseases. Engineered capsids with enhanced tropism and lower immunogenicity have been proposed, along with constructs designed for targeted and controlled expression. Additionally, several pathways implicated in the pathogenesis of these conditions have been targeted with single or multigene expression cassettes, gene editing and silencing approaches. This review discusses strategies employed in AAV-based gene therapies for glaucoma and non-infectious uveitis and provides an overview of current progress and future directions.
Affine Bruhat order and Demazure products
Authors: Schremmer Felix 
Published: April 2024

Abstract
We give new descriptions of the Bruhat order and Demazure products of affine Weyl groups in terms of the weight function of the quantum Bruhat graph. These results can be understood to describe certain closure relations concerning the Iwahori–Bruhat decomposition of an algebraic group. As an application towards affine Deligne–Lusztig varieties, we present a new formula for generic Newton points.
Status and influencing factors of nurses’ burnout: A cross-sectional study during COVID-19 regular prevention and control in Jiangsu Province, China
Authors: Mao Xiaofei , Hou Tianya , Wang Hao , Tang Yun , Ni Chunyan , Zhang Yulin , Zhang Jianguo , Deng Wenxi , Chen Liqing , Wang Xingxing , Li Ziqiang , Jia Yan , Dong Wei , Qian Xing 
Published: April 2024

Abstract

Background
Chinese nurses working with immense stress may have issues with burnout during COVID-19 regular prevention and control. There were a few studies investigating status of burnout and associated factors among Chinese nurses. However, the relationships remained unclear.

Objectives
To investigate status and associated factors of nurses’ burnout during COVID-19 regular prevention and control.

Methods
784 nurses completed questionnaires including demographics, Generalized Anxiety Disorder-7, Patient Health Questionnaire-9, Insomnia Severity Index, Impact of Event Scale-revised, Perceived Social Support Scale, Connor–Davidson Resilience Scale, General Self-efficacy Scale and Maslach Burnout Inventory.

Results
310 (39.5%), 393 (50.1%) and 576 (73.5%) of respondents were at high risk of emotional exhaustion (EE), depersonalization (DP) and reduced personal accomplishment (PA). The risk of EE, DP and reduced PA were moderate, high and high. Nurses with intermediate and senior professional rank and title and worked >40 h every week had lower scores in EE. Those worked in low-risk department reported lower scores in PA. Anxiety, post-traumatic stress disorder (PTSD), self-efficacy and social support were influencing factors of EE and DP, while social support and resilience were associated factors of PA.

Conclusion
Chinese nurses’ burnout during COVID-19 regular prevention and control was serious. Professional rank and title, working unit, weekly working hours, anxiety, PTSD, self-efficacy, social support and resilience were associated factors of burnout.
DISCONTINUOUS HOMOMORPHISMS OF WITH
Authors: DUMAS BOB A. 
Published: April 2024

AbstractAssume that M is a transitive model of
$ZFC+CH$
containing a simplified
$(\omega _1,2)$
-morass,
$P\in M$
is the poset adding
$\aleph _3$
generic reals and G is P-generic over M. In M we construct a function between sets of terms in the forcing language, that interpreted in
$M[G]$
is an
$\mathbb R$
-linear order-preserving monomorphism from the finite elements of an ultrapower of the reals, over a non-principal ultrafilter on
$\omega $
, into the Esterle algebra of formal power series. Therefore it is consistent that
$2^{\aleph _0}>\aleph _2$
and, for any infinite compact Hausdorff space X, there exists a discontinuous homomorphism of
$C(X)$
, the algebra of continuous real-valued functions on X.
Multiple Large Shareholders, Identity, and Corporate Tax Avoidance
Authors: Huyghebaert Nancy , Kang Shaoqing , Wang Lihong , Wu Wenfeng 
Published: April 2024

AbstractIn recent years, the variation in firms' tax-avoidance behavior has attracted a lot of attention, both theoretically and empirically. This study investigates the governance role of multiple large shareholders in firms' tax-avoidance behavior, using a sample of Chinese state-controlled listed firms over the period 2004–2016. We find that the ownership stake of a firm's largest shareholder is negatively associated with tax avoidance among state-controlled firms. Second, other large non-state shareholders negatively affect tax avoidance of state-controlled firms. The former effect is particularly strong when the local government is the controlling shareholder. Finally, differences in institutional quality influence the largest shareholder's tendency to engage in tax avoidance in state-controlled firms. For state-controlled firms, a better institutional environment elicits more tax avoidance and thus curtails minority-investor expropriation.
Comparisons between dual-energy X-ray absorptiometry and bioimpedance devices for appendicular lean mass and muscle quality in Hispanic adults
Authors: Nassar Bassel , Tinsley Grant M. , Park Kyung-Shin , Czerwinski Stefan A. , Nickerson Brett S. 
Published: April 2024

AbstractThe purpose of this study was to compare single- and multi-frequency bioimpedance (BIA) devices against dual-energy X-ray absorptiometry (DXA) for appendicular lean mass (ALM) and muscle quality index (MQI) metrics in Hispanic adults. One hundred thirty-one Hispanic adults (18–55 years) participated in this study. ALM was measured with single-frequency bioimpedance analysis (SFBIA), multi-frequency bioimpedance analysis (MFBIA) and DXA. ALMTOTAL (left arm + right arm + left leg + right leg) and ALMARMS (left arm + right arm) were computed for all three devices. Handgrip strength (HGS) was measured using a dynamometer. The average HGS was used for all MQI models (highest left hand + highest right hand)/2. MQIARMS was defined as the ratio between HGS and ALMARMS. MQITOTAL was established as the ratio between HGS and ALMTOTAL. SFBIA and MFBIA had strong correlations with DXA for all ALM and MQI metrics (Lin’s concordance correlation coefficient values ranged from 0·86 (MQIMFBIA-ARMS) to 0·97 (Arms LMSFBIA); all P < 0·001). Equivalence testing varied between methods (e.g. SFBIA v. DXA) when examining the different metrics (i.e. ALMTOTAL, ALMARMS, MQITOTAL and MQIARMS). MQIARMS was the only metric that did not differ from the line of identity and had no proportional bias when comparing all the devices against each other. The current study findings demonstrate good overall agreement between SFBIA, MFBIA and DXA for ALMTOTAL and ALMARMS in a Hispanic population. However, SFBIA and MFBIA have better agreement with DXA when used to compute MQIARMS than MQITOTAL.
A remark on a conjecture on the symmetric Gaussian problem
Authors: Fusco Nicola , La Manna Domenico Angelo 
Published: April 2024

AbstractIn this paper, we study the functional given by the integral of the mean curvature of a convex set with Gaussian weight with Gaussian volume constraint. It was conjectured that the ball centred at the origin is the only minimizer of such a functional for certain values of the mass. We prove that this is the case in dimension 2 while in higher dimension the situation is different. In fact, for small values of mass, the ball centred at the origin is a local minimizer, while for larger values the ball is a maximizer among convex sets with a uniform bound on the curvature.
Twisted Blanchfield pairings and twisted signatures III: Applications
Authors: Borodzik Maciej , Conway Anthony , Politarczyk Wojciech 
Published: April 2024

AbstractThis paper describes how to compute algorithmically certain twisted signature invariants of a knot
$K$
using twisted Blanchfield forms. An illustration of the algorithm is implemented on
$(2,q)$
-torus knots. Additionally, using satellite formulas for these invariants, we also show how to obstruct the sliceness of certain iterated torus knots.
Nutritional status of schoolchildren before and after confinement by COVID-19 (2019–2021) in Jujuy, Argentina
Authors: Bustamante María José , Solis Juan Manuel , Tabera Celia Margarita , Maraz Natalia , Gutiérrez Gisela Belén del Rosario , Dipierri José Edgardo 
Published: April 2024

AbstractAn increase in the prevalence of obesity due to lockdown and confinement linked to COVID-19 is observed. Variations in the nutritional status of schoolchildren from Jujuy are analyzed in relation to confinement due to COVID-19 (2019–2021) and its relationship with socio-demographic variables and the school environment. This is an observational, descriptive study. Data from 56,695 schoolchildren aged 6–18 years old is analyzed based on two temporary cuts (2019 pre-confinement and 2021 post-confinement). The nutritional status of schoolchildren (underweight, overweight, and obese) was established using the IOTF (International Obesity Task Force) criterion. The prevalence of each nutritional phenotype was estimated by sex and age group, considering the following independent variables: setting (rural/urban), school management system (public/private), geographic altitude, and percentage of households with unmet basic needs (UBN) in the place where they attend school. Multiple proportions contrast was performed using Fisher's test, a transition matrix ws produced and a statistical model of proportional odds was fitted. It was observed that between 2019 and 2021, the prevalence of underweight decreased and the prevalence of overweight and obesity increased significantly. In 2021, 67% of schoolchildren maintained the same nutritional category that they had in 2019, 21% gained weight and 12% lost weight. The model explains about 52% of the total variability observed. The factors that are significantly correlated in the model are school cycle, age, geographic altitude, school setting, and % of households with UBN. The results indicate that during the COVID-19 pandemic, there was a shift to the right in the distribution of the nutritional status categories of the schoolchildren population in Jujuy, with a decrease in the prevalence of underweight and an increase in the prevalence of overweight and obesity with variations related to age, school location, geographic altitude, and socioeconomic characteristics of the households in the place where the children attended school.
Ultrasonography-guided drainage versus surgical drainage for deep neck space abscesses: a systematic review and meta-analysis
Authors: Alzaid Mohammad , Ramadhan Mohammed , Abul Ahmad , Karam Mohammad , Alsaif Abdulmalik , Stapleton Emma 
Published: April 2024

AbstractObjectiveTo compare ultrasonography-guided drainage versus conventional surgical incision and drainage in deep neck space abscesses.MethodsThe study was pre-registered on the National Institute of Health Research Prospective Register of Systematic Reviews (CRD42023466809) and adhered to Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. The Medline, Embase and Central databases were searched. Primary outcomes were length of hospital stay and recurrence. Heterogeneity and bias risk were assessed, and a fixed-effects model was applied.ResultsOf 646 screened articles, 7 studies enrolling 384 participants were included. Ultrasonography-guided drainage was associated with a significantly shorter hospital stay (mean difference = −2.31, p < 0.00001), but no statistically significant difference was noted in recurrence rate compared to incision and drainage (odds ratio = 2.02, p = 0.21). Ultrasonography-guided drainage appeared to be associated with cost savings and better cosmetic outcomes.ConclusionUltrasonography-guided drainage was associated with a shorter hospital stay, making it a viable and perhaps more cost-effective alternative. More randomised trials with adequate outcomes reporting are recommended to optimise the available evidence.
Multiple and frequent trypanosomatid co-infections of insects: the Cuban case study
Authors: Votýpka Jan , Zeman Šimon , Stříbrná Eva , Pajer Petr , Bartoš Oldřich , Kment Petr , Lukeš Julius , Lukeš Julius 
Published: April 2024

AbstractTrypanosomatids are obligate parasites of animals, predominantly insects and vertebrates, and flowering plants. Monoxenous species, representing the vast majority of trypanosomatid diversity, develop in a single host, whereas dixenous species cycle between two hosts, of which primarily insect serves as a vector. To explore in-depth the diversity of insect trypanosomatids including their co-infections, sequence profiling of their 18S rRNA gene was used for true bugs (Hemiptera; 18% infection rate) and flies (Diptera; 10%) in Cuba. Out of 48 species (molecular operational taxonomic units) belonging to the genera Vickermania (16 spp.), Blastocrithidia (7), Obscuromonas (4), Phytomonas (5), Leptomonas/Crithidia (5), Herpetomonas (5), Wallacemonas (2), Kentomonas (1), Angomonas (1) and two unnamed genera (1 + 1), 38 species have been encountered for the first time. The detected Wallacemonas and Angomonas species constitute the most basal lineages of their respective genera, while Vickermania emerged as the most diverse group. The finding of Leptomonas seymouri, which is known to rarely infect humans, confirms that Dysdercus bugs are its natural hosts. A clear association of Phytomonas with the heteropteran family Pentatomidae hints at its narrow host association with the insect rather than plant hosts. With a focus on multiple infections of a single fly host, using deep Nanopore sequencing of 18S rRNA, we have identified co-infections with up to 8 trypanosomatid species. The fly midgut was usually occupied by several Vickermania species, while Herpetomonas and/or Kentomonas species prevailed in the hindgut. Metabarcoding was instrumental for analysing extensive co-infections and also allowed the identification of trypanosomatid lineages and genera.
Severe weather events and cryptosporidiosis in Aotearoa New Zealand: A case series of space–time clusters
Authors: Grout Leah , Hales Simon , Baker Michael G. , French Nigel , Wilson Nick 
Published: April 2024

Abstract
Occurrence of cryptosporidiosis has been associated with weather conditions in many settings internationally. We explored statistical clusters of human cryptosporidiosis and their relationship with severe weather events in New Zealand (NZ). Notified cases of cryptosporidiosis from 1997 to 2015 were obtained from the national surveillance system. Retrospective space–time permutation was used to identify statistical clusters. Cluster data were compared to severe weather events in a national database. SaTScan analysis detected 38 statistically significant cryptosporidiosis clusters. Around a third (34.2%, 13/38) of these clusters showed temporal and spatial alignment with severe weather events. Of these, nearly half (46.2%, 6/13) occurred in the spring. Only five (38%, 5/13) of these clusters corresponded to a previously reported cryptosporidiosis outbreak. This study provides additional evidence that severe weather events may contribute to the development of some cryptosporidiosis clusters. Further research on this association is needed as rainfall intensity is projected to rise in NZ due to climate change. The findings also provide further arguments for upgrading the quality of drinking water sources to minimize contamination with pathogens from runoff from livestock agriculture.
A 2-categorical proof of Frobenius for fibrations defined from a generic point
Authors: Hazratpour Sina , Riehl Emily 
Published: April 2024

AbstractConsider a locally cartesian closed category with an object
$\mathbb{I}$
and a class of trivial fibrations, which admit sections and are stable under pushforward and retract as arrows. Define the fibrations to be those maps whose Leibniz exponential with the generic point of
$\mathbb{I}$
defines a trivial fibration. Then the fibrations are also closed under pushforward.
Redox imbalance accompanies loss of viability in seeds of two cacti species buried in situ
Authors: Guzmán-Hernández David A. , Barbosa-Martínez Claudia , Villa-Hernández Juan M. , Pérez-Flores Laura J. 
Published: April 2024

AbstractThis work provides insights into the deterioration of cacti seeds of Escontria chiotilla (F.A.C. Weber ex K. Schum) and Stenocereus pruinosus (Otto ex Pfeiff.) Buxbaum stored ex situ at 25 °C, under dry and dark conditions or buried in situ conditions in a xerophytic shrubland. Viability, germination speed, electrolyte leakage and indicators of the redox balance including glutathione content, glutathione half-cell reduction potential (EGSSG/2GSH) and malondialdehyde (MDA), oxidized protein content, together with water-soluble antioxidant enzyme activity were assessed. Over a period of two years of storage, viability was maintained when seeds were stored ex situ at 7–9% water content compared to seeds buried in the soil. A second burial experiment showed that seeds of E. chiotilla maintained viability during a year of storage that included a rainy season followed by a dry season. Thereafter, they died rapidly during the second rainy season. In contrast, those of S. pruinosus started to lose viability after 6 months of burial at the end of the rainy season and were mostly dead at the end of the dry season. This difference in persistence between species was related to a difference in the glutathione content and antioxidant enzyme activities. In both storage experiments, the loss of viability of both species was associated to a EGSSG/2GSH shift to a more oxidative state during burial. Yet, contents in MDA and oxidized soluble proteins were not related to redox imbalance and loss of viability, indicating that these compounds are not good markers of oxidative stress in cacti seeds during storage.
SPHERICAL REPRESENTATIONS FOR
$\boldsymbol C^{\boldsymbol {*}}$
-FLOWS III: WEIGHT-EXTENDED BRANCHING GRAPHS
Authors: UEDA YOSHIMICHI 
Published: April 2024

AbstractWe apply Takesaki’s and Connes’s ideas on structure analysis for type III factors to the study of links (a short term of Markov kernels) appearing in asymptotic representation theory.