bluuebunny/crossref_metadata_2025_split huggingface dataset:
Formulation and evaluation of bio-grease from the blend of chemically modified rice bran oil and Calophyllum inophyllum oil
Authors: Prasanth M. A. , Rani S. , Singh S Prathap , Raja D. Elil , Barmavatu Praveen 
Published: March 2024

AbstractVegetable oils are a highly promising alternative to produce various lubricants, owing to their biodegradability and eco-friendliness. In comparison to mineral oil, these oils possess a higher flash point and viscosity index, along with superior lubricating properties. Additionally, most of the vegetable oils are easily accessible in local markets in India. However, their industrial application is limited by poor thermal and oxidative stability, which can be addressed through chemical modification, the addition of appropriate additives, or by blending these oils. Greases, characterized by their semi-solid consistency, are widely used lubricants. Most of the grease production is based on mineral oils as base oil and lithium soap as a thickener. These materials are not only non-biodegradable but also scarce and have health implications. Consequently, biodegradable grease represents an eco-friendly and healthy alternative. Grease made using vegetable oils with the required properties has the potential to bring about revolutionary changes. The present work focuses on the feasibility of using chemically modified blended rice bran oil (RBO) and Calophyllum inophyllum oil (CIO) as a bio-lubricant. The oils undergo a two-step modification process, involving a transesterification reaction followed by epoxidation. Significant improvements have been observed in the chemical properties (acid, peroxide, and iodine values) of transesterified epoxidized rice bran oil Calophyllum inophyllum oil mixture–50:50 (ETRCIO) when compared with Unmodified Rice bran oil Calophyllum inophyllum oil mixture–50:50 (RCIO). The acid value, peroxide value, and iodine value improved by 91.66%, 87.08%, and 15.78% respectively. The rheological, tribological, and chemical properties of the blended samples have been evaluated and compared to pure oils using American Society for Testing and Materials (ASTM) and Indian Standards (IS). Additionally, ETRCIO was used to develop a bio-grease, and its tribological properties were extensively analyzed. The mean coefficient of friction (COF) and wear scar diameter (WSD) of the ETRCIO grease sample improved by 10.20% and 29.32% respectively when compared with that of commercially available grease. These findings indicate that the ETRCIO bio-grease exhibits superior tribological properties in comparison to commercially available grease.
Research on the influence of geological factors on casing stress in casing-in-casing cementing in the horizontal section of shale gas wells
Authors: Zheng Youzhi , Zhao Jun , Hu Xihui , Li Zhilin , Zhang Zhanwu , Guo Ziming , He Yu , He Lang , Chen Yong , Xie Yi 
Published: March 2024

AbstractDeep shale gas development has great potential, but the frequent occurrence of shale gas well casing change problems triggered by geological factors seriously restricts deep shale gas development. In order to investigate the influence of geological factors on the casing stress of the cemented casing in the sleeve, a model of formation-cement sheath-double casing assemblage was established, and the influence of three-way geostress and fault slip on the casing stress of the casing-in-casing cementing was investigated by using finite element analysis. The results show the following: the smaller the difference between the vertical geostress and the maximum horizontal geostress is, the lower the equivalent force on the casing is, and when the difference gradually decreases from 20 to 7 MPa, the maximum equivalent force of the inner casing under fracturing condition decreases by 9.4%; the increase of the minimum horizontal geostress leads to the increase of the equivalent force of the inner and outer casing. When the minimum horizontal stress gradually increases from 80 to 90 MPa, the maximum equivalent force of the inner casing under fracturing condition increases by 5.9%. The larger the fault slip and the fault angle, the larger the equivalent force generated on the casing. The shear resistance of the double-layer casing is significantly greater than that of the single-layer casing, with an average increase in fault slip distance that can be withstood of about 45.25% and 40.2% in the no internal pressure and fracturing conditions. The larger the casing steel grade and the thicker the wall thickness, the higher the shear resistance. It is recommended to reduce placing of wells in areas where the difference between the vertical and maximum horizontal ground stresses is large, and at locations where the fault slip angle is large, and to use both higher steel grades and larger wall thicknesses of casing. This research result demonstrates the feasibility of “milling + casing-in-casing” technology in severe casing change wells and also provides useful guidance for the application of this technology in the field.
Potassium Iodide Use and Patient Outcomes for Thyroid Storm: An Observational Study
Authors: Matsuo Yuichiro , Miyawaki Atsushi , Watanabe Hideaki , Matsui Hiroki , Fushimi Kiyohide , Yasunaga Hideo 
Published: March 2024

Abstract

Context
Iodine, combined with antithyroid drugs, is recommended as an initial pharmacologic treatment for thyroid storm according to some clinical guidelines. However, the clinical efficacy of iodine in managing thyroid storm remains unexplored.

Objective
This study aimed to determine whether early potassium iodide (KI) use is associated with mortality in patients hospitalized for thyroid storm.

Methods
Using the Japanese Diagnosis Procedure Combination database, we identified patients hospitalized with thyroid storm between July 2010 and March 2022. We compared in-hospital mortality, length of stay, and total hospitalization costs between patients who received KI within 2 days of admission (KI group) vs those who did not (non-KI group). Prespecified subgroup analyses were performed based on the presence of the diagnosis of Graves’ disease.

Results
Among 3188 eligible patients, 2350 received KI within 2 days of admission. The crude in-hospital mortality was 6.1% (143/2350) in the KI group and 7.8% (65/838) in the non-KI group. After adjusting for potential confounders, KI use was not significantly associated with in-hospital mortality (odds ratio [OR] for KI use, 0.91; 95% CI, 0.62-1.34). In patients with the diagnosis of Graves’ disease, in-hospital mortality was lower in the KI group than in the non-KI group (OR, 0.46; 95% CI, 0.25-0.88). No significant difference in in-hospital mortality was observed in patients without the diagnosis of Graves’ disease (OR, 1.11; 95% CI, 0.67-1.85). Length of stay was shorter (subdistribution hazard ratio, 1.15; 95% CI, 1.05-1.27), and total hospitalization costs were lower (OR, 0.92; 95% CI, 0.85-1.00) in the KI group compared with the non-KI group.

Conclusion
Our findings suggest that KI may reduce in-hospital mortality among patients hospitalized for thyroid storm with Graves’ disease.
Clinicopathological Predictors of Positive Resection Margins in Breast-Conserving Surgery
Authors: Chauhan Hemali , Jiwa Natasha , Nagarajan Vikneswaran Raj , Thiruchelvam Paul , Hogben Katy , Al-Mufti Ragheed , Hadjiminas Dimitri , Shousha Sami , Cutress Ramsey , Ashrafian Hutan , Takats Zoltan , Leff Daniel Richard 
Published: March 2024

Abstract
Background
Ductal carcinoma in situ (DCIS) is associated with risk of positive resection margins following breast-conserving surgery (BCS) and subsequent reoperation. Prior reports grossly underestimate the risk of margin positivity with IBC containing a DCIS component (IBC + DCIS) due to patient-level rather than margin-level analysis.

Objective
The aim of this study was to delineate the relative risk of IBC + DCIS compared with pure IBC (without a DCIS component) on margin positivity through detailed margin-level interrogation.

Methods
A single institution, retrospective, observational cohort study was conducted in which pathology databases were evaluated to identify patients who underwent BCS over 5 years (2014–2019). Margin-level interrogation included granular detail into the extent, pathological subtype and grade of disease at each resection margin. Predictors of a positive margin were computed using multivariate regression analysis.

Results
Clinicopathological details were examined from 5454 margins from 909 women. The relative risk of a positive margin with IBC + DCIS versus pure IBC was 8.76 (95% confidence interval [CI] 6.64–11.56) applying UK Association of Breast Surgery guidelines, and 8.44 (95% CI 6.57–10.84) applying the Society of Surgical Oncology/American Society for Radiation Oncology guidelines. Independent predictors of margin positivity included younger patient age (0.033, 95% CI 0.006–0.060), lower specimen weight (0.045, 95% CI 0.020–0.069), multifocality (0.256, 95% CI 0.137–0.376), lymphovascular invasion (0.138, 95% CI 0.068–0.208) and comedonecrosis (0.113, 95% CI 0.040–0.185).

Conclusions
Compared with pure IBC, the relative risk of a positive margin with IBC + DCIS is approximately ninefold, significantly higher than prior estimates. This margin-level methodology is believed to represent the impact of DCIS more accurately on margin positivity in IBC.
Computational design and in vitro assay of lantadene-based novel inhibitors of NS3 protease of dengue virus
Authors: Mujwar Somdutt , Pal Jyoti , Sharma Manu , Tiwari Abhishek , Tiwari Varsha , Kumar Manish , Verma Shivani , Qurtam Ashraf Ahmed , Nasr Fahd A. , Al-Zharani Mohammed , Alhalmi Abdulsalam 
Published: March 2024

Abstract
Dengue virus (DENV) infection is one of the diseases for which no drug is available for the treatment. The DENV NS2B-NS3 protease is considered to be the prime target for anti-dengue drug development because of its importance in the development of new virus subunits via DENV poly-protein breakdown. Pentacyclic triterpenoids (Lantadenes) from the weed Lantana camara L. and its semi-synthetic congeners have shown a wide array of biological activities in the last two decades. The virtual screening strategy was used on the library of 78 natural and semi-synthetic lantadenes to predict the potent antagonists for the NS2B-NS3 protease enzyme of DENV and their experimental validation by in vitro assay of lead molecules. In the in silico analysis of 78 triterpenoids, two lead molecules (−10.60 and −9.93 kcal/mol) were predicted to be inhibitors of protease (viral) when compared to its reference ligand 1,8-dihydroxy-4,5-dinitroanthraquinone (−5.377 kcal/mol). At the same time, binding affinity, pharmacokinetic, and toxicity profiling, along with molecular dynamics simulations, were studied. The in vitro viral infection inhibition assay inferred that lead molecule 62 exhibited a 60% and 45% reduction in DENV titers at 10 and 5 µM concentrations, respectively. The lead molecule 62 can further be optimized for its pharmacophore and has the potential to be developed as a drug-like molecule.
Machine translation as a form of feedback on L2 writing
Authors: Sasaki Miyuki , Mizumoto Atsushi , Matsuda Paul Kei 
Published: March 2024

Abstract
With advances in artificial intelligence (AI), many language teachers have started exploring the classroom implications of AI-powered technology, including machine translation (MT). To examine the usefulness of MT technology in writing instruction, we conducted a mixed-methods study comparing two types of written feedback: comprehensive direct Teacher Corrective Feedback (TCF), and MT feedback. Participants were 23 Japanese university students in an intact L2 writing classroom. Sample size adequacy was confirmed through a priori power analysis. Participants were instructed to describe a picture prompt in L2 English and then in L1 Japanese. Half the participants received first TCF then MT on their L2 English text, while the order was reversed for the other half. Participants in both conditions were then asked to study the feedback and describe the same picture prompt without the feedback. In the following phase, both groups completed the same tasks in reverse order. Participants also responded to a survey exploring their engagement with the feedback. Results reveal that: 1) TCF improved complexity; 2) MT improved accuracy and fluency; and 3) variation in outcomes may be explained by the different ways in which participants engaged with both TCF and MT. Implications for appropriate classroom use of MT are discussed.
A Water Resource Consumption Control Method for Energy Development Bases Based on IoT Technology and Energy–Water Correlation Law
Authors: Bai Dan , Li Jun , Wang Tao 
Published: March 2024

Abstract
To achieve the rational development and utilization of water resources in energy development bases and sustainable economic and social development, research is conducted on the control method of water resource consumption in energy development bases based on the law of energy–water correlation. Using Internet of Things technology to collect water resource consumption data from energy development bases, based on the results of data collection, taking Shanxi Coal Development Base as the research area, based on the objective relationship between energy and water, a multiregion input–output model and linear programming model are established, with objective functions and constraints set to achieve water resource consumption control in energy development bases. Under the dual constraint scenario of energy con-servation and water conservation, the optimization effect of the industrial structure of the water resource carrying capacity level in the research area is explored. The outcomes show that the water resource in the research area can bear 1,949.58 billion Yuan for 22.0336 million people. The water resources holding capacity is at the general level. Based on the limitations of energy consumption, raising the share of the mining sector and decreasing the share of the industrial and commercial service sectors can minimize the overall consumption of energy and water resources while ensuring the growth of the local economy. Reducing the extent of agricultural expansion supports both water conservation and regional economic growth because water resource consumption is constrained. A clear difference in the production and utilization effect of energy resource per unit will result from the direction difference in structural adjustment of the mining industry, which is based on the dual restrictions of energy–water resource.
Dimensional Accuracy of a Hole Diameter Produced by Material Extrusion
Authors: Bayraklilar M. Said 
Published: March 2024

Abstract
Three-dimensional printing technology has become one of the key areas of Industry 4.0, as it allows complex geometries to be produced on site without wasting material. However, there are still shortcomings in terms of product quality and cost. Because dimensional accuracy is one of the most important parameters for product quality, researchers are working to improve dimensional accuracy. However, most studies have focused on the dimensional accuracy of holes in the z-axis. Because additive manufacturing is a layer-by-layer manufacturing method, the dimensional accuracy of holes in the x- and y-axes will be very different from that of holes in the z-axis. In this study, the effect of printing parameters on the dimensional accuracy of holes of different diameters and axes produced by additive manufacturing from different materials was investigated. The Taguchi experimental design was used to avoid wastage of material and time. Analysis of variance was used to determine the most effective parameter, and the experimental results were estimated using artificial neural networks. Because of this study, it was concluded that it is not possible to find a single optimum parameter for holes with different axes and diameters. It was observed that as the hole diameter decreased, the heat generated during production affected the dimensional accuracy by heating the previous hole surfaces, and even small holes were not formed in some parameters.
Mechanical Behavior and Life Prediction of a Low Nickel/High Nitrogen Austenitic Steel under Pure Torsion, Uniaxial Tension-Compression, and Multiaxial Fatigue
Authors: Ngeru Timothy , Kurtulan Dzhem , Hanke Stefanie 
Published: March 2024

Abstract
Fatigue life prediction, crack growth, and propagation mechanisms are important details to consider for a structure to be used in service without fear of early failure. This is especially important for a new material for which very limited information is available. In this study, austenitic stainless steel P558 with low nickel content and high nitrogen content was subjected to fatigue testing at room temperature in multiaxial (static compression and cyclic torsion), pure torsion, and uniaxial tension-compression modes. The material generally depicts cyclic softening in the three loading conditions; although the multiaxial experiments experienced some initial hardening, those with a high shear stress and axial stress combination furthermore experienced a secondary hardening before softening. The Fatemi-Socie model predicts the pure torsion and multiaxial fatigue well but fails to predict fatigue lives for uniaxial tension-compression. On the other hand, the Smith-Watson-Topper model predicts fatigue lives for the uniaxial fatigue and pure torsion sufficiently but is poor in predicting fatigue lives for the multiaxial fatigue loading conditions. The cracking behavior was observed to be dependent on the loading condition and the strain amplitude with Mode II cracks or shear-oriented cracks observed for the high strain amplitudes (resulting in shorter lives) whereas Mode I cracks, or tensile-oriented cracks, were observed from low strain amplitudes (resulting in higher lives). A mixed mode was also observed for specimens in the midrange strain amplitudes, which exhibited a branching from shear to tensile cracks. The static compressive stress is believed to have a negative influence on the cracking behavior and the fatigue life by the rubbing of the crack surfaces, which in turn reduces the load-holding capability of the material. The same friction at the crack tip could also be the reason for the heating up of the specimens.
Katri Ratia, <i>Alternative Spirituality, Counterculture, and European Rainbow Gatherings: Pachamama, I’m Coming Home</i>
Authors: Wildcroft Theo 
Published: March 2024

Katri Ratia, Alternative Spirituality, Counterculture, and European Rainbow Gatherings: Pachamama, I’m Coming Home (Abingdon: Taylor & Francis, 2023), 294pp., £35.09 (ebk), ISBN: 978-1-003-33343-2
Practical Instrumental Analysis
Authors: Srivastava Bajarang Bali Lal , Mishra Amarnath , Woyessa Girma Workeneh 
Published: March 2024

Analytical chemistry is the rapidly progressing branch of chemistry, which deals with the study of analytical tools with matter. Thus, the novel techniques emerging in analytical chemistry are facilitating quick and reliable measurement. The primary objective of book entitled Fundamental of analytical chemistry is to provide fundamental knowledge of the analytical principles. The massive scope of the subject dictates the all-possible visual assistance is avoidable to the students. This has done by presenting a large no of questions and examples serve to reinforce as well as assist the students to learning the subject. The present edition designed to use as a textbook as well as competitive book by the students of B.Sc. and M.Sc. It is also serve as a reference manual for practisiging ananlytical chemists and research students.

The unique features of the book are

<!--[if !supportLists]-->v <!--[endif]-->The book provides quick access to every important principle.

<!--[if !supportLists]-->v <!--[endif]-->Every chapter is equipped with important points and relations followed by solved examples.

<!--[if !supportLists]-->v <!--[endif]-->It reflect recent advancement in the field of analytical chemistry

<!--[if !supportLists]-->v <!--[endif]-->It provides the latest text to the students for their excellent grasp of the subject and easy success in the examination.

The author will feed amply reward if the book serves the purpose of the students to the best of their knowledge.

I wish to express to my deep appreciation to Mr. Rakesh Pandit of Innovative publication for extending me excellent cooperative in this venture.

Constructive criticism and useful suggestions for further improvement of the book will be gratefully receive and acknowledged.

Dr. B. B. L. Srivastava
Dr. Amarnath Mishra

Visit at http://www.drrittuchandel.com for more biochemistry and explanation. Any kind of suggestion and criticism is most welcome
Physiology MCQ for All India Postgraduate Medical Entrance Examinations
Authors: D.M. Dr. Chetan , L. Dr. Raghavendra H. , Mallikarjuna Dr. Rachappa. M. , Nalawade Dr. Triveni. M. 
Published: March 2024

This set of MCQs based on the different topics of Physiology is made for the aspirants of PG Medical and for Physiology student. This set has very relevant question and it covers MCQs in depth.

Silent features:

<!--[if !supportLists]-->1. <!--[endif]-->The MCQs covered and designed from each chapter in depth.

<!--[if !supportLists]-->2. <!--[endif]-->Discover what students know about a topic prior to teaching. Design the MCQs based on the knowledge.

Involve students in higher-level thinking questions and extending activities.
Practical Lab Manual of Pharmaceutical Organic Chemistry - I, B. Pharm 2nd Semester (As Per PCI Syllabus)
Authors: Dwivedi Dr. Shivendra Kumar 
Published: March 2024

This book having the "Practical Lab Manual of Pharmaceutical Organic Chemistry - I" as per PCI regulation, written with an intention to benefit the B. Pharma students for easy understanding.
In Pharmaceutical Chemistry it is very important to have sensitive, accurate, precise, and selective methods of synthesis and characterization for crude drugs. A sincere attempt has been made to prepare the content simple, concise, and easy to understand. The content of each experiment is further arranged conceptually and logically to maintain the flow of information.
The present handbook could be beneficial not only to the pharmacy students, but it could be helpful to other chemistry-related courses also. We hope that students and teachers of pharmacy as well as pharmaceutical chemistry synthesis in the pharmaceutical industry find this book very useful. Particularly this book includes PCI New Syllabus for B. Pharmacy (2nd Semester) students to carry out the experiments of Organic Chemistry - I.