bluuebunny/crossref_metadata_2025_split huggingface dataset:
WITHDRAWN: Enhancing Wound Healing: Formulation and Evaluation of Acalypha Fruticosa Ethosomal Gel
Authors: Haq Mohammed Misbah Ul 
Published: March 2024

Abstract
Background
This study focuses on the development of both topical and ethosomal gels utilizing an Ethanolic extract of A. fruticosa with the goal of improving patient adherence. The ethosomal gels, labeled as E1 to E8, were created using a composition consisting of 10% ethanol and 2% phospholipid. Various assessments were conducted on these gels to explore their properties and potential benefits.
Results
The diffusion studies revealed noteworthy drug release percentages, with optimized formulations such as E2 and E6 showing 92.4% and 96.45% release within a 6-hour duration, respectively. These formulations, utilizing 10% and 20% Ethosomal gels of A. fruticosa, exhibited characteristics such as effortless removal, excellent spreadability, and a smooth texture without any gritty sensation. Thorough examinations were conducted to evaluate in vitro drug release and accelerated stability of the ethosomal gel. Remarkably, formulation E6, containing 20% v/v ethanol, demonstrated the highest entrapment efficiency at 96.45%. Notably, E6 exhibited promising outcomes with a 97.15% drug release after 6 hours. Additional characteristics of E6 included a pH level of 7.0, viscosity measuring at 20888 cps, a Zeta potential of -29.3 (mV), and distinctive vesicular shape and size as observed through SEM analysis.
Conclusions
In conclusion, the study suggests that the formulation E6, with its enhanced drug release, entrapment efficiency, and favorable physicochemical properties, holds promise for further development as a topical and ethosomal gel utilizing the Ethanolic extract of A. fruticosa. These findings contribute to the potential improvement of patient adherence in topical medication applications.
Machine Learning Analysis to Identify Factors Associated with Requesting Tobacco Cessation Services Among Users of an Online Self-Diagnostic Questionnaire in Mexico.
Authors: Hernández-Llanes Norberto Francisco , Sánchez-Domínguez Ricardo , Alvarez-Reza Sofía , Fernández-Cáceres Carmen , Marín-Navarrete Rodrigo 
Published: March 2024

Abstract
Introduction: While traditional cessation services exist, internet-based options are gaining popularity. However, understanding online users' unique characteristics compared to traditional users is crucial. This study utilize machine learning (ML), aimed to identify these online users and their needs.
Method: Through analyzing 14,182 records of adults who completed online nicotine dependence screening questionnaire, a random forest algorithm plus oversampling was used to predict request services.
Results: The algorithm accurately identified 78.6% of users and rejected 68.8% of non-users. Notably, age, sex, dependence severity indicators, certain locations, and even specific occasions like World No Tobacco Day, were identified as key factors influencing service request.
Discussion: These findings suggest the effectiveness of random forest algorithm in predicting potential users. Moreover, the predictor variables offer valuable insights for crafting targeted prevention and awareness campaigns, potentially leading to improved campaign effectiveness and ultimately, helping more individuals seeking cessation support.
Relationship between Eating Disorder (Anorexia Nervosa) and Autism Spectrum Disorder (ASD)
Authors: Suratwala T 
Published: March 2024

Abstract
OBJECTIVE:
Research has shown there is a potential link between Eating Disorders (Anorexia Nervosa) and Autism Spectrum Disorder (ASD). This quantitative study aimed to evaluate if there was a significant difference between those with AN and those without when assessing for ASD.
METHOD:
100 participants aged 18 years and above, including n = 50 who did not have Anorexia and n = 50 who declared themselves to have Anorexia, used a pre-screening and online questionnaire, with a between-subject design and Independent Samples T-Tests in SPSS.
RESULTS:
The study found a link between AN and ASD, with a higher incidence of ASD among those with AN. However, the study excluded those under 18 and excluded participants over 51, potentially underrepresenting the overall age population. Additionally, no gender distinction was made in the results, focusing on the overall association between AN and ASD.
CONCLUSION:
Further research is needed to determine if gender differences affect the results and if a greater prevalence of ASD among AN still exists, particularly in younger and older generations, to ensure consistency and validity in the findings.
Equipping Llama with Google Query API for Improved Accuracy and Reduced Hallucination
Authors: Bae Yeong Sik , Kim Hye Rin , Kim Jae Hoon 
Published: March 2024

Abstract
This study investigates the integration of the Llama 2 7b large language model (LLM) with the Google Query API to enhance its accuracy and reduce hallucination instances. By leveraging real-time internet data, we aimed to address the limitations of static training datasets and improve the model's performance across various language processing tasks. The methodology involved augmenting Llama 2 7b's architecture to incorporate dynamic data retrieval from the Google Query API, followed by an evaluation of its impact on model accuracy and hallucination reduction using the BIG-Bench benchmark. The results indicate significant improvements in both accuracy and reliability, demonstrating the effectiveness of integrating LLMs with external data sources. This integration not only marks a substantial advancement in the capabilities of LLMs but also raises important considerations regarding data bias, privacy, and the ethical use of internet-sourced information. The study's findings contribute to the ongoing discourse on enhancing LLMs, suggesting a promising direction for future research and development in artificial intelligence.
Design of an Automated Neonatal Chest Compression Device to Aid in Cardiopulmonary Resuscitation
Authors: Balapangu Srinivasan S. , Agyemang Bright , Domey Ernestina , Bortei Michael Sango , Tebi Thibaut Kwadzo 
Published: March 2024

Abstract
This research work focuses on the design and development of a neonatal chest compression device to be used during surgical operations and critical situations requiring chest compressions in infants within hospital Neonatal Intensive Care Units (NICUs). The primary objective was to overcome the limitations associated with manual chest compressions in infants and enhance blood perfusion. The devised prototype incorporates a compressed air-actuated pneumatic cylinder positioned above the infant's chest, which is supplied with compressed air from a portable air compressor. The airflow is regulated by a three-way solenoid valve, and a microcontroller controls the compression process. The proposed method utilizes a combination of pneumatic compression and electrical components to achieve a target compression rate of 80-120 compressions per minute, exerting a force of 48-50 newtons. The compression depth, equal to one-third of the manikin's chest width, is achieved by carefully controlling the deactivation time of the solenoid coil to approximately 50 milliseconds. To facilitate user operation, a smartphone-based interface was developed using the blynk Internet of Things (IoT) software. Through extensive testing, the device demonstrated adherence to fundamental biological specifications for chest compression forces and rates. However, further research is required to ensure the mechanical integrity of materials and perform rigorous testing on a SimNewB or suitable biological substitute to implement crucial safety aspects.
Weight gain-mediated recovery of metabolic and gut microbiome impairments in a TDP-43 mouse model of ALS
Authors: Romero-Muñoz Laura , Sanz-Martos Ana Belén , Cabrera-Pinto Marta , Cano Victoria , Olmo Nuria Del , Valiente Nicolas , Seseña Susana , Atkinson Rachel AK , Sreedha Jemeen , King Anna , Fernandez-Martos Carmen M. 
Published: March 2024

Abstract
There is increasing interest in the use of hypercaloric diets in patients with the neurodegenerative disease amyotrophic lateral sclerosis (ALS), as gaining weight, and subsequently fat mass, has been associated with better survival in patients with ALS. However, the precise mechanisms by which nutritional state modifies the onset or progression of ALS remain unclear. We therefore investigated the effects of a short-term high fat (HF) diet treatment (8 weeks) in male NEFH-tTA/tetO-hTDP-43ΔNLS (rNLS mice). This hypercaloric nutritional intervention mitigated motor decline and increased weight in rNLS mice without influencing age of disease onset. HF diet did not alter the disease-associated atrophy of hindlimb tibialis anterior muscle in rNLS mice, and did not correct hippocampal long-term potentiation impairment. However, HF diet did alter glial cell population changes in the hippocampus and cortex of rNLS mice. HF diet also improved glucose homeostasis and reduced plasma metabolic disturbances present in rNLS mice. In addition, we present the first evidence of a significant shift in the gut microbiome of rNLS mice in response to the nutritional intervention. Together, we demonstrate specific improvements in metabolic disturbances of ALS in male rNLS mice, providing, to our knowledge, the first insights to the benefit of this approach to mitigate metabolic alterations in ALS.
Consequence of less water availability on farming over three decades: A Case Study of Aligarh, Uttar Pradesh, India
Authors: Singh Daya Shanlar , Gupta Tanu Priya , Gupta Antara , Mishra Ajai , Gautam Pawan Kumar Gautam 
Published: March 2024

Abstract
This research delves into the relationship between water availability and crop yield. Availability of water for irrigation can been classified in to two parts surface water or ground water (Blue Water) and precipitated water (Green Water). Using data spanning three decades, we observed significant trends in crop production and cultivation influenced by less (Green) water availability and tells that farmers are changing the cropping pattern what they grow based on which water is available easily or cost effectively or low water footprint value. Notably, crops with high water footprint value, such as Barley and Sugarcane, have seen a decline, whereas crops requiring low water footprint value, like Potato and Rice, have shown an uptick. Employing advanced statistical methods, the Karl Pearson Correlation matrix, the study identifies distinct inverse relationships between crop groups; revealing differential water consumption metrics. Notably, crops groups that usually need a lot of water (blue and green or high water footprint value) are not growing as well anymore. On the other hand, types of crops that can survive with less water (blue or low water footprint value) are becoming more popular. This shows that farmers are growing drought-resistant crop varieties that is not because of water conservation, because of less water availability. This narrative underscores the urgent need for the adoption of water-efficient techniques and crop choices while highlighting the imperative of addressing the intricate interplay between water resources, and agricultural practices.
Drying Kinetics and Effectiveness of Button Mushrooms (Agaricus bisporus) at Different Conditions of Sublimation Process
Authors: Mierzejewska Sylwia , Kopeć Adam , Stepuk Joanna Piepiórka , Diakun Jarosław , Domiszewski Zdzisław 
Published: March 2024

Abstract
The drying process in the vacuum chamber included a fresh and pre-frozen button mushrooms. During the process, the pressure and the weight of the sample were recorded as well as the temperatures: inside the vacuum chamber, at the surface of the mushroom and in the center. The kinetics of the measured parameters are presented and their interdependence is shown The drying process under sublimation conditions for the pre-frozen mushroom was the shortest. This was an unexpected result, as the unfrozen mushroom it required less energy for water evaporation. The sublimation conditions of the pre-frozen mushrooms showed the best quality.
Criticism of The Methods Of Interpretation Yusuf Al-Qardawi Against The Hadith Rukyat Hilal
Authors: Mufid Abdul 
Published: March 2024

Abstract
The main source for Muslims in understanding Islamic teachings is the Koran and Hadith. For Muslims, the Hadith second ranks after the Koran. Throughout Islamic history, hadith is a source of controversy in Islamic law. Among the problems that are still warm and almost always occur today is an understanding of the observations of the crescent related to the determination of the beginning of the Islamic month. Questioning about the differences in determining the beginning of the Hijri month is the result of different perspectives to understand the hadith about crescent observations. Therefore, the method of understanding the hadith about "crescent observation" is very urgent to be investigated more deeply. The conclusion of this literature-based research process can be seen that the impact of Yusuf al-Qaradawi's understanding of the Hilal rukyat traditions of Hilal is al-Qaradawi's hope to unite fasting and Eid al-Fitr in Europe based on priorities, not unifying all Muslims in the hemisphere of the earth.
Keywords: Al-Qaradawi, Hadith, Observation.
Abstrak
Sumber utama bagi umat Islam dalam memahami ajaran Islam adalah Alquran dan Hadis. Bagi umat Islam, hadis menduduki peringkat kedua setelah Alquran. Sepanjang sejarah Islam, hadis merupakan sumber kontroversi dalam hukum Islam. di antara masalah yang masih hangat dan hampir sering terjadi saat ini adalah pemahaman tentang observasi bulan sabit terkait penentuan awal bulan Hijriah. Menyoal tentang perbedaan dalam menentukan awal bulan Hijriah adalah hasil dari perspektif yang berbeda untuk memahami hadis tentang pengamatan bulan sabit. Oleh karena itu, metode memahami hadis tentang "pengamatan bulan sabit" sangat mendesak untuk diteliti secara lebih mendalam. Kesimpulan akhir dari proses penelitian berbasis kepustakaan ini dapat dilihat bahwa dampak dari pemahaman Yusuf al-Qaradawi terhadap hadis-hadis rukyat hilal Hilal adalah harapan al-Qaradawi untuk menyatukan puasa dan idul fitri di Eropa atas dasar prioritas, bukan menyatukan semua Muslim di belahan muka bumi.
Kata kunci : Al-Qaradawi, Hadis, Observasi.
The Movement Of Islamic Fundamentalism The Classical, Pre-Modern And Contemporary
Authors: Anshor Ahmad Muhtadi 
Published: March 2024

Abstract
Religious fundamentalism is understood as an answer of the socialist group and the political elite of the religious in a religious group. So religious fundamentalism is always evolving in the modern era. As a study-based literature, this study will highlight the historical roots of religious fundamentalism in the era of the classical, pre-modern, and contemporary implications in the discovery model the thinking of fundamentalism religious in the contemporary era. The findings in this study show that fundamentalism has a few basic principles. Principles basic principles: the first is oppositional (understand resistance), the second the rejection of hermeneutics, the third rejection of pluralism and relativism, and the fourth is the rejection of the historical development and sociological. By using basic principles such then the movement of the Kharijites, the Wahabi movement in the Arabian peninsula, the movement of Shaykh Uthman and Fodio in Northern Nigeria, the movement Padri in Minangkabau and Al-Ikhwan al-Muslim in Egypt can be categorized in the movement of Islamic fundamentalism.
Keywords: Islamic Fundamentalism, classical, pre-modern, contemporary.
Abstrak
Fundamentalisme agama difahami sebagai sebuah jawaban dari kelompok sosialis dan elit politik keagamaan dalam sebuah kelompok agama. Sehingga fundamentalisme agama ini selalu berkembang dalam era modern saat ini. Sebagai kajian berbasis pustaka, kajian ini akan menyorot akar sejarah fundamentalisme agama pada era klasik, pra-modern, dan kontemporer yang berimplikasi pada penemuan model pemikiran fundamentalisme keagamaan pada era kontemporer. Temuan dalam kajian ini menunjukkan bahwa fundamentalisme memiliki beberapa prinsip dasar. Prinsip-prinsip dasar tersebut: pertama adalah oppositionalism (paham perlawanan), kedua penolakan terhadap hermeneutika, ketiga penolakan terhadap pluralisme dan relativisme, dan keempat adalah penolakan terhadap perkembangan historis dan sosiologis. Dengan menggunakan prinsip-prinsip dasar tersebut maka gerakan kaum Khawarij, gerakan Wahabi di semenanjung Arabia, gerakan Syaikh Usman dan Fodio di Nigeria Utara, gerakan Padri di Minangkabau dan Al-Ikhwan al-Muslimun di Mesir dapat dikategorikan dalam gerakan fundamentalisme Islam.
Kata Kunci : Fundamentalisme Islam, klasik, pra-modern, kontemporer.
Realizing The Religion As The Source Of Harmony In A Multicultural Society
Authors: Izzuddin Izzuddin , Fata Ahmad Khoirul 
Published: March 2024

Abstract
This paper examines the potential of religion as the main source of harmony in a plural society. This paper itself is motivated by the fact that religion has two different faces: integrative and confrontational. On the one hand religion can encourage integration in society, however religion also has the potential to cause conflict and tension in the community, especially in the people with complex levels of diversity. In multicultural societies, integrative religious attitudes are needed to avoid conflicts. But making it happen is not as easy as turning our hand. The factor of understanding religious texts that are exclusive and based on hatred is one of the challenges. This will be further complicated when external factors (economic, political) are involved. By using philosophical-reflective methods, the writer offers two ways of religious that can create harmony in different cultures and beliefs, namely: exclusivenes-tolerance religious, and willingness to engage in interfaith dialogue. With these two things the writer believes that religious people still feel comfortable with the truth of their own religion, and at the same time they live in peace with people of different religions.
Keywords: Diversity, Conflict, Multicultural Society, Exclusive-Tolerant, interfaith Dialogue.
Abstrak
Tulisan ini mengkaji tentang potensi agama sebagai sumber utama harmoni dalam masyarakat majemuk. Tulisan ini sendiri dilatar belakangi oleh kenyataan bahwa agama memiliki dua wajah yang saling berbeda: integratif dan konfrontatif. Di satu sisi agama bisa mendorong terjadinya integrasi dalam masyarakat, namun demikian agama juga berpotensi menimbulkan konflik dan ketegangan di tengah masyarakat, khususnya masyarakat dengan tingkat keragaman yang kompleks.Dalam masyarakat multikultural, sikap beragama yang integratif sangat diperlukan agar tidak terjadi konflik. Namun mewujudkannya tidak semudah membalikkan tangan. Faktor pemahaman terhadap teks-teks keagamaan yang tertutup dan didasari kebencian menjadi salah satu tantangan. Ini akan semakin rumit ketika faktor-faktor eksternal (ekonomi, politik) turut terlibat. Dengan menggunakan metode filosofis-reflektif penulis menawarkan dua cara beragama yang bisa mewujudkan harmoni dalam masyarakat yang berbeda budaya dan keyakinan, yaitu: keberagamaan yang ekslusif-toleran, dan kesediaan diri untuk melakukan dialog antarumat beragama. Dengan dua hal ini penulis meyakini umat beragama tetap merasa nyaman dengan kebenaran agamanya sendiri, dan di saat bersamaan mereka hidup damai dengan umat agama yang berbeda.
Kata Kunci : Keberagamaan, Konflik, Masyarakat Multikultural, Ekslusif-Toleran, Dialog Antaragama.
Reading Hizb Ghozali In Boarding School Luqmaniyyah Yogyakarta
Authors: Rahmanto Oki Dwi 
Published: March 2024

Abstract
Reading Hizb Ghozali in Pondok Pesantren Luqmaniyyah Yogyakarta Hizib Ghozali is one of the many benefits of Hizb. As for the practice, Santri must do the Tirakat. Besides, Tirakat of Santri is obliged to do readings Hizib Ghozali every day. If Santri violates will be punished by the caretaker of Pesantren Luqmaniyyah Yogyakarta. By using Karl Mannheim's Sociology of knowledge theory, it is hoped that this research could reveal meaning the Santri in the reading of Hizb Ghozali. Karl Mannheim discusses in detail the behavioural behaviour and meaning of human behaviour. Karl Mannheim distinguishes between three different meanings in social action, i.e. objective, expressive and documentary meaning. As for the results of this research, the objective meaning contained in the reading Hizb Ghozali in Pondok Pesantren Luqmaniyyah is reading Hizib Ghozali is a form of Ijazahan from Kyai Na'im as caretaker of Pesantren Luqmaniyyah, besides, the recitation of Hizb Ghozali believed to grant all the Hajat desired. The meaning of expressive is the recitation of Hizb Ghozali performed by the students because of the sense of Ta'dzim on the teacher and can be trusted to give many benefits. The meaning of the documentary in the reading of Hizb Ghozali is the recitation of Hizb Ghozali in Pondok Pesantren Luqmaniyyah Yogyakarta is a practice that can be a thorough culture..
Keywords: Hizib Ghozali, Karl Mannheim's, Sociology of knowledge theory.
Abstrak
Membaca Hizib Ghozali dalam Pondok Pesantren Luqmaniyyah Yogyakarta, Hizib Ghozali adalah salah satu banyak manfaat dari Hizib. Adapun prakteknya, Santri harus melakukan Tirakat tertentu. Selain itu, Tirakat Santri wajib melakukan pembacaan Hizib Ghozali setiap hari. Jika Santri melanggar akan dihukum oleh penjaga Pesantren Luqmaniyah Yogyakarta. Dengan menggunakan Karl Mannheim tentang ilmu pengetahuan teori, diharapkan bahwa penelitian ini dapat mengungkapkan makna Santri dalam membaca Hizb Ghozali. Karl Mannheim membahas secara rinci perilaku dan makna perilaku manusia. Karl Mannheim membedakan antara tiga makna berbeda dalam aksi sosial, seperti makna, ekspresif dan dokumenter. Adapun hasil penelitian ini, tujuan yang terkandung dalam membaca Hizb Ghozali di Pondok Pesantren Luqmaniyyah adalah bentuk dari Ijazahan dari Kyai Na'im sebagai pengurus dari Pondok Pesantren Luqmaniyyah. Makna ekspresif pembacaan Hizib Ghozali dilakukan oleh Santri karena rasa takdzim pada Kyai dan dapat dipercaya untuk memberikan banyak keuntungan. Makna dari film dokumenter dalam pembacaan dari Hizib Ghozali adalah pembacaan dari Hizb Ghozali di Pondok Pesantren Luqmaniyyah Yogyakarta adalah latihan yang dapat menjadi budaya menyeluruh.
Kata Kunci : Hizib Ghozali, Karl Mannheim, Sosiologi Teori Pengetahuan.
Occurrence of coliforms and biofilm-forming bacteria in raw, treated, and distributed water from two waterwork systems in Osun State, Southwestern Nigeria
Authors: Oyewale Abayomi Tolulope , Odetoyin Babatunde Wumi , Oluduro Anthonia Olufunke , Adeniyi Israel Funso 
Published: March 2024

Abstract

This study assessed the bacteriological quality of raw, treated, and distributed water from Ede-Erinle and Opa reservoirs in Osun State, Nigeria. This was to determine the potability of water from these waterwork stations. Eighteen sampling points were established across the two reservoir networks for this study. Samples were collected bi-monthly for two annual cycles. Serial dilution and pour plate methods were employed for the enumeration of bacterial load. Total heterotrophic bacteria count (THBC) and total coliform bacteria count (TCBC) were enumerated on nutrient and MacConkey agar at 37 °C, respectively. Bacterial isolates were characterized using biochemical identification methods with reference to Bergey's Manual of Determinative Bacteriology. Bacterial isolates and biofilm formation were further identified molecularly through the PCR method using specific universal primers. Mean values of THBC and TCBC in distributed water from Ede-Erinle (9.61 × 104 ± 1.50 × 104 CFU/mL; 69.56 ± 26.81 CFU/mL) and Opa waterworks (9.58 × 104 ± 2.55 × 104 CFU/mL; 142.94 ± 44.41 CFU/mL) exceeded permissible limits for drinking water. Paenibacillus lautus, Bacillus pseudomycoides, Pseudomonas aeruginosa, and Pseudomonas stutzeri showed biofilm-forming capacity. The study concluded that the presence of coliforms and biofilm-forming bacteria in distributed water implies that the water is unfit for consumption without further treatment.