bluuebunny/crossref_metadata_2025_split huggingface dataset:
Electrical properties of Al/CZTSe nanocrystal Schottky diode
Authors: Kişnişci Z. , Özel F. , Karadeniz S. , Tuğluoğlu N. , Özel S. S. , Yüksel Ö. F. 
Published: April 2024

AbstractIn this study, electrical changes in diode parameters of Schottky diodes that made of a kesterite semiconductor were examined under different temperatures. For this aim, Cu2ZnSnSe4 (CZTSe) nanocrystals were fabricated using the hot injection technique, and it was covered by spin coating on an ITO glass substrate. We was introduced the physical and structural analyses using scanning electron microscopy and X-ray spectroscopy. Current–voltage measurements were fulfilled at different temperature (from 100 to 325 K) under dark environment. It was observed that its electrical parameters were strongly affected by temperature.
Effect of vertical stopcock position on start-up fluid delivery in syringe pumps used for microinfusions
Authors: Weiss Markus , Wendel-Garcia Pedro David , Grass Beate , Kleine-Brueggeney Maren 
Published: April 2024

AbstractThe purpose of this in vitro study was to evaluate the impact of the vertical level of the stopcock connecting the infusion line to the central venous catheter on start-up fluid delivery in microinfusions. Start-up fluid delivery was measured under standardized conditions with the syringe outlet and liquid flow sensors positioned at heart level (0 cm) and exposed to a simulated CVP of 10 mmHg at a set flow rate of 1 ml/h. Flow and intraluminal pressures were measured with the infusion line connected to the stopcock primarily placed at vertical levels of 0 cm, + 30 cm and − 30 cm or primarily placed at 0 cm and secondarily, after connecting the infusion line, displaced to + 30 cm and − 30 cm. Start-up fluid delivery 10 s after opening the stopcock placed at zero level and after opening the stopcock primarily connected at zero level and secondary displaced to vertical levels of + 30 cm and – 30 cm were similar (− 10.52 [− 13.85 to − 7.19] µL; − 8.84 [− 12.34 to − 5.33] µL and − 11.19 [− 13.71 to − 8.67] µL (p = 0.469)). Fluid delivered at 360 s related to 65% (zero level), 71% (+ 30 cm) and 67% (− 30 cm) of calculated infusion volume (p = 0.395). Start-up fluid delivery with the stopcock primarily placed at + 30 cm and − 30 cm resulted in large anterograde and retrograde fluid volumes of 34.39 [33.43 to 35.34] µL and − 24.90 [− 27.79 to − 22.01] µL at 10 s, respectively (p < 0.0001). Fluid delivered with the stopcock primarily placed at + 30 cm and − 30 cm resulted in 140% and 35% of calculated volume at 360 s, respectively (p < 0.0001). Syringe infusion pumps should ideally be connected to the stopcock positioned at heart level in order to minimize the amounts of anterograde and retrograde fluid volumes after opening of the stopcock.
On optimizing the experimental setup for estimation of the thermal conductivity of thin films
Authors: Barragán V. M. , Pastuschuk E. , Maroto J. C. , Martín A. , Muñoz S. 
Published: April 2024

AbstractThe aim of this study is to show the optimal arrangement of a measurement system for estimating the thermal conductivity of thin films from temperature profiles. For this purpose, two different experimental setup systems, with square and circular cross sections, were designed to estimate the thermal conductivity of thin films and, in particular, of two ion exchange membranes. Both systems were placed horizontally and vertically in order to evaluate the best orientation to more accurately determine thermal conductivity. A three-dimensional numerical simulation was performed using Comsol Multiphysics to predict the heat flow and temperature gradient and to evaluate the effect of the geometry and the orientation on the contact resistances. Each system was first calibrated without the membrane inside in order to estimate all the necessary thermal properties of the different materials of the model. Next, the membrane was placed inside the model, so that the model now includes the thermal conductivity of the membrane as the only unknown parameter. The numerical results were compared with the various measured temperature profiles to estimate the thermal conductivity. The thermal conductivity values of the well-known Nafion 117 membrane and other thicker membrane were determined. A very good agreement with reliable literature values was obtained. The approach presented here, combining experimental and simulated temperature profiles, may provide the basis for a practical alternative to better estimate the thermal conductivity of thin films.
Shared pooled mobility essential complement to decarbonize China’s transport sector until 2060
Authors: Hu Jiawei , Ayaragarnchanakul Eva , Yang Zheng , Creutzig Felix 
Published: April 2024

AbstractGreenhouse gas emission reduction in the passenger transport sector is a main challenge for China’s climate mitigation agenda. Electrification and shared mobility provide encouraging options for carbon emissions reduction in road transport. Based on an integrated scenario-based assessment framework, a provincial-level projection is made for vehicle growth and CO2 emissions in China under shared socioeconomic pathways (SSPs). This work illustrates how passenger car electrification and sharing contribute to China’s “30·60” climate goals (peaking of CO2 emissions by 2030 and carbon neutrality by 2060). The results demonstrate that China is en route to achieving the goal of a 2030 carbon peak (1.0Gt CO2) under current conditions, and could reach peak emissions around 2026 with optimistic growth in EVs and shared mobility. Compared with no policy action, the single EV policy (shifting from ICEVs to EVs) can reduce 71% of emissions by 2060, thus narrowing but not closing the mitigation gap to carbon neutrality in passenger cars (302 Mt CO2). Shared mobility can provide further emission reduction support, reducing emissions by 83% in 2060. Comprehensive climate actions (including electrification, sharing mobility to reduce car use, and improving vehicle efficiency and fuel carbon intensity) are needed to achieve deep decarbonization to net-zero by 2060 in the passenger transport sector.
Targeting myocardial inflammation: investigating the therapeutic potential of atrial natriuretic peptide in atrial fibrosis
Authors: Zhu Nana , Li Tianlun , Bai Yili , Sun Jiao , Guo Jianping , Yuan Hongtao , Shan Zhaoliang 
Published: April 2024

Abstract

Background
Atrial Fibrillation (AF), a prevalent arrhythmic condition, is intricately associated with atrial fibrosis, a major pathological contributor. Central to the development of atrial fibrosis is myocardial inflammation. This study focuses on Atrial Natriuretic Peptide (ANP) and its role in mitigating atrial fibrosis, aiming to elucidate the specific mechanisms by which ANP exerts its effects, with an emphasis on fibroblast dynamics.

Methods and results
The study involved forty Sprague-Dawley rats, divided into four groups: control, Angiotensin II (Ang II), Ang II + ANP, and ANP only. The administration of 1 µg/kg/min Ang II was given to Ang II and Ang II + ANP groups, while both Ang II + ANP and ANP groups received 0.1 µg/kg/min ANP intravenously for a duration of 14 days. Cardiac fibroblasts were used for in vitro validation of the proposed mechanisms. The study observed that rats in the Ang II and Ang II + ANP groups showed an increase in blood pressure and a decrease in body weight, more pronounced in the Ang II group. Diastolic dysfunction, a characteristic of the Ang II group, was alleviated by ANP. Additionally, ANP significantly reduced Ang II-induced atrial fibrosis, myofibroblast proliferation, collagen overexpression, macrophage infiltration, and the elevated expression of Interleukin 6 (IL-6) and Tenascin-C (TN-C). Transcriptomic sequencing indicated enhanced PI3K/Akt signaling in the Ang II group. Furthermore, in vitro studies showed that ANP, along with the PI3K inhibitor LY294002, effectively reduced PI3K/Akt pathway activation and the expression of TN-C, collagen-I, and collagen-III, which were induced by Ang II.

Conclusions
The study demonstrates ANP’s potential in inhibiting myocardial inflammation and reducing atrial fibrosis. Notably, ANP’s effect in countering atrial fibrosis seems to be mediated through the suppression of the Ang II-induced PI3K/Akt-Tenascin-C signaling pathway. These insights enhance our understanding of AF pathogenesis and position ANP as a potential therapeutic agent for treating atrial fibrosis.
Draft Genome Sequence of Candida saopaulonensis from a Very Premature Infant with Sepsis
Authors: Ning Ya-Ting , Dai Rong-Chen , Luo Zheng-Yu , Xiao Meng , Xu Yingchun , Yan Qun , Zhang Li 
Published: April 2024

AbstractThe rare fungus Candida saopaulonensis has never been reported to be associated with human infection. We report the draft genome sequence of the first clinical isolate of C. saopaulonensis, which was isolated from a very premature infant with sepsis. This is the first genome assembly reaching the near-complete chromosomal level with structural annotation for this species, opening up avenues for exploring evolutionary patterns and genetic mechanisms of pathogenesis.
Identifying anomalous patterns in ecological communities’ diversity: leveraging functional boxplots and clustering of normalized Hill’s numbers and their integral functions
Authors: Porreca Annamaria , Maturo Fabrizio 
Published: April 2024

AbstractDiversity is fundamental in many disciplines, such as ecology, business, biology, and medicine. From a statistical perspective, calculating a measure of diversity, whatever the context of reference, always poses the same methodological challenges. For example, in the ecological field, although biodiversity is widely recognised as a positive element of an ecosystem, and there are decades of studies in this regard, there is no consensus measure to evaluate it. The problem is that diversity is a complex, multidimensional, and multivariate concept. Limiting to the idea of diversity as variety, recent studies have presented functional data analysis to deal with diversity profiles and their inherently high-dimensional nature. A limitation of this recent research is that the identification of anomalies currently still focuses on univariate measures of biodiversity. This study proposes an original approach to identifying anomalous patterns in environmental communities’ biodiversity by leveraging functional boxplots and functional clustering. The latter approaches are implemented to standardised and normalised Hill’s numbers treating them as functional data and Hill’s numbers integral functions. Each of these functional transformations offers a peculiar and exciting point of view and interpretation. This research is valuable for identifying warning signs that precede pathological situations of biodiversity loss and the presence of possible pollutants.
Conceptualizing the landscape of digital health entrepreneurship: a systematic review and research agenda
Authors: Weimar Sascha Noel , Martjan Rahel Sophie , Terzidis Orestis 
Published: April 2024

AbstractDigital health, which encompasses the use of digital technology to enhance and support healthcare, can potentially transform the healthcare industry. As healthcare systems struggle to provide high-quality care, entrepreneurs and startups have turned to digital health technology to create innovative products and services that aim at improving healthcare outcomes and reducing costs. This has made digital health entrepreneurship a major driving force for achieving good health and high-quality care. The study aims to analyze the current state of research in digital health entrepreneurship by identifying contributing disciplines and common research themes. A comprehensive literature review based on state-of-the-art definitions of digital health entrepreneurship was conducted to achieve this goal. A total of 164 articles met the final inclusion criteria, and the subsequent inductive analysis revealed the presence of three contributing disciplines and ten distinct themes: Academia Transfer and Education, Ecosystem and Stakeholder, Product and Business Development, Business Model, Classification, Management and Strategy, Regulation, Digital Technology, Implementation and Adoption, and Evaluation. These themes were organized into a conceptual framework depicting the internal and external building blocks of digital health entrepreneurship. The review highlights the importance of a structured understanding of the industry, including its business models and regulatory environment, as well as the role of the various healthcare stakeholders. This analysis can guide researchers and entrepreneurs seeking to navigate the digital health landscape and proposes further research avenues.
Long-term exposure of endangered Danube sturgeon (Acipenser gueldenstaedtii) to bisphenol A (BPA): growth, behavioral, histological, genotoxic, and hematological evaluation
Authors: Minaz Mert , Kurtoğlu İlker Zeki 
Published: April 2024

AbstractDanube sturgeon (Acipenser gueldenstaedtii) which is identified as endangered species can be exposed to pollutants such as bisphenol A (BPA) that have a disruptive effect on the endocrine system at any time. Starting from this motivation, the current study focused on BPA toxicity in A. gueldenstaedtii juvenile individuals and its adverse effects in sub-lethal concentration. The median lethal concentration (LC50) of BPA was 5.03 mg/L in 96th hour. In the chronic period, 0.625 mg/L and 1.25 mg/L BPA concentrations were evaluated based on the result of acute study. Accordingly, growth performance was significantly decreased in BPA groups (1.25 mg/L BPA group was significantly lowest) compared to control (p < 0.05). In the acute period, behavioral disorders were standing at the bottom/corner of tank, slowing and stopping of gill movement, decreased response to stimuli, and death, respectively. While vacuolization was severe in the liver tissue of the fish in the acute period, intense necrosis and melanomacrophage centers were observed in the chronic period. In terms of genotoxicity, longer DNA migration was observed in all groups exposed to BPA than in the control group. In addition, lower erythrocyte and hemoglobin were observed in the BPA groups compared to control. As a result, the current study revealed toxic effect of BPA on A. gueldenstaedtii juvenile individuals and its negative results on fish physiology.
The Puzzle of Dion and Theon Solved
Authors: Baber H. E. 
Published: April 2024

AbstractDion is a human person, Lefty is his left foot, and Theon is Lefty-Complement, a proper part of Dion. Lefty is annihilated and Dion survives left-footless. After Lefty’s annihilation Theon, if he survives, occupies the same region as Dion. I suggest that this scenario be understood as a fusion case in which Dion and Theon, initially overlapping but distinct, are identical after Lefty’s annihilation and propose an account of proper names that allows us to say that Dion and Theon have ‘become identical’ without commitment to occasional identity or other controversial metaphysical doctrines. The proposed solution employs the semantics developed by Wolfgang Schwarz to address the ‘paradox of occasional identity’, posed by puzzle cases of fission, to deal with the problem of Dion and Theon, a body-minus puzzle.
Advancing understanding of learning experience design: refining and clarifying definitions using an eDelphi study approach
Authors: Tawfik Andrew , Schmidt Matthew , Payne Linda , Huang Rui 
Published: April 2024

AbstractWe report findings from an eDelphi study that aimed to explore 16 expert panelists’ perspectives regarding the key attributes of learning experience design (LXD) as it relates to the following: design, disciplines, methods, and theory. Findings suggest consensus was reached regarding LXD’s focus on learner-centrism and incorporating human-centered design practices to design learning environments. LXD practitioners adapt methods and theories from fields such as human–computer interaction and user experience. Implications suggest a need to develop specific methods and theories within our own field.
Experimental investigations of water retention curves of fresh and decomposed municipal solid wastes under multiple drying and wetting cycles
Authors: Xie Yuekai , Xue Jianfeng 
Published: April 2024

AbstractMunicipal solid wastes (MSWs) disposed in landfills are generally exposed to drying and wetting cycles because of the variation in environmental conditions, decomposition of organics and leachate recirculation. This paper studies the water retention curves (WRCs) of fresh and degraded MSWs under various numbers of drying and wetting cycles with water and leachate exposure. The result indicates that the water retention capacities of MSWs decrease with drying and wetting cycles. The maximum hysteresis between the drying and wetting cycles is observed in the first cycles for all MSW samples. The WRCs of medium to highly decomposed MSWs under drying and wetting cycles are similar to those of soils. The WRCs of fresh MSWs can undergo substantial changes due to the discharge of intra-particle moisture caused by decomposition and compression. For both fresh and decomposed MSWs, the WRCs stabilize after 3 drying and wetting cycles. However, only the MSWs of one initial composition with similar void ratios were investigated. Further research should be conducted to investigate the water retention behavior of MSWs with diverse initial compositions (e.g., food contents) and void ratios.
Born Global Maturity: Strategic Aspects and Performance Consequences
Authors: Efrat Kalanit , Asseraf Yoel 
Published: April 2024

AbstractBorn global firms (BGs) contribute significantly to economic growth, but few studies have examined the post-internationalization stage of BGs. In addition, studies of the impact of changes in strategic aspects as BGs mature on BG performance and survival have yielded conflicting results. To address this gap in knowledge, the present study examines the relationships between intelligence generation and innovation orientation, and branding strategies as moderated by maturity. The data were received from 133 senior managers of BGs of various ages. The analysis shows that BG maturity negatively moderates the relationship between intelligence generation and functional branding strategy but does not influence the relationships of innovation orientation with branding strategies. Furthermore, emotional branding showed stable association with both financial and market performance indicators. This study demonstrates that maturity affects the orientations and performance of BGs and calls for a reassessment of the competitive international strategy of BGs at the post-entry stage.
An Approach to Evolutionary Sociology and its Implications for Theorizing on Socio-Cultural Evolution
Authors: Maryanski Alexandra , Turner Jonathan H. 
Published: April 2024

AbstractA theoretical research program is outlined that seeks to use the Modern Synthesis in explaining human evolution, but also recognizes its limitations in explaining the evolution of socio-cultural systems. The universe, from a human perspective, is composed of physical, biological, and socio-cultural dimensions, each revealing unique properties and dynamics. In the case of the socio-cultural universe, modern evolutionary theory is relevant for some explanations, but not to the degree assumed by socio-biology, evolutionary psychology, and even co-evolutionary models. The program proposed is built around social network theory, cladistic analysis, and comparative neuro-anatomy, and outlines where biological analysis is appropriate and useful. An understanding of the biological basis of human behavior will allow sociologists to develop theoretical approaches to explaining the emergent properties of the socio-cultural universe. The strategy outlined will allow us to see what a mature evolutionary sociology can do: develop abstract theoretical laws about the dynamics of selection on socio-cultural formations in human societies.
Enhancing discharge decision-making through continuous monitoring in an acute admission ward: a randomized controlled trial
Authors: Kant Niels , Garssen Sjoerd H. , Vernooij Carlijn A. , Mauritz Gert-Jan , Koning Mark V. , Bosch Frank H. , Doggen Carine J. M. 
Published: April 2024

AbstractIn Acute Admission Wards, vital signs are commonly measured only intermittently. This may result in failure to detect early signs of patient deterioration and impede timely identification of patient stability, ultimately leading to prolonged stays and avoidable hospital admissions. Therefore, continuous vital sign monitoring may improve hospital efficacy. The objective of this randomized controlled trial was to evaluate the effect of continuous monitoring on the proportion of patients safely discharged home directly from an Acute Admission Ward. Patients were randomized to either the control group, which received usual care, or the sensor group, which additionally received continuous monitoring using a wearable sensor. The continuous measurements could be considered in discharge decision-making by physicians during the daily bedside rounds. Safe discharge was defined as no unplanned readmissions, emergency department revisits or deaths, within 30 days after discharge. Additionally, length of stay, the number of Intensive Care Unit admissions and Rapid Response Team calls were assessed. In total, 400 patients were randomized, of which 394 completed follow-up, with 196 assigned to the sensor group and 198 to the control group. The proportion of patients safely discharged home was 33.2% in the sensor group and 30.8% in the control group (p = 0.62). No significant differences were observed in secondary outcomes. The trial was terminated prematurely due to futility. In conclusion, continuous monitoring did not have an effect on the proportion of patients safely discharged from an Acute Admission Ward. Implementation challenges of continuous monitoring may have contributed to the lack of effect observed. Trial registration: https://clinicaltrials.gov/ct2/show/NCT05181111. Registered: January 6, 2022.
Sequences of Operators, Monotone in the Sense of Contractive Domination
Authors: Hassi S. , de Snoo H. S. V. 
Published: April 2024

AbstractA sequence of operators $$T_n$$

T
n

from a Hilbert space $${{\mathfrak {H}}}$$
H
to Hilbert spaces $${{\mathfrak {K}}}_n$$

K
n

which is nondecreasing in the sense of contractive domination is shown to have a limit which is still a linear operator T from $${{\mathfrak {H}}}$$
H
to a Hilbert space $${{\mathfrak {K}}}$$
K
. Moreover, the closability or closedness of $$T_n$$

T
n

is preserved in the limit. The closures converge likewise and the connection between the limits is investigated. There is no similar way of dealing directly with linear relations. However, the sequence of closures is still nondecreasing and then the convergence is governed by the monotonicity principle. There are some related results for nonincreasing sequences.