bluuebunny/crossref_metadata_2025_split huggingface dataset:
Health Insurance Navigation Tools Intervention: A Pilot Trial Within the Childhood Cancer Survivor Study
Authors: Park Elyse R. , Kirchhoff Anne C. , Donelan Karen , Perez Giselle K. , McDonald Aaron , Bliss Cayley C. , Foor Allyson , van Thiel Berghuijs Karely M. , Waters Austin R. , Durieux Natalie , Leisenring Wendy , Armstrong Gregory T. , Ponzani Colin , Lopez Ana , Vaca Lopez Perla L. , Battaglia Tracy , Galbraith Alison A. , Kuhlthau Karen A. 
Published: March 2024

PURPOSE Childhood cancer survivors are at increased risk for underinsurance and health insurance–related financial burden. Interventions targeting health insurance literacy (HIL) to improve the ability to understand and use health insurance are needed. METHODS We codeveloped a four-session health insurance navigation tools (HINT) intervention, delivered synchronously by a patient navigator, and a corresponding booklet. We conducted a randomized pilot trial with survivors from the Childhood Cancer Survivor Study comparing HINT with enhanced usual care (EUC; booklet). We assessed feasibility, acceptability, and preliminary efficacy (HIL, primary outcome; knowledge and confidence with health insurance terms and activity) on a 5-month survey and exit interviews. RESULTS Among 231 invited, 82 (32.5%) survivors enrolled (53.7% female; median age 39 years, 75.6% had employer-sponsored insurance). Baseline HIL scores were low (mean = 28.5; 16-64; lower scores better); many lacked knowledge of Affordable Care Act (ACA) provisions. 80.5% completed four HINT sessions, and 93.9% completed the follow-up survey. Participants rated HINT's helpfulness a mean of 8.9 (0-10). Exit interviews confirmed HINT's acceptability, specifically its virtual and personalized delivery and helpfulness in building confidence in understanding one's coverage. Compared with EUC, HINT significantly improved HIL (effect size = 0.94. P < .001), ACA provisions knowledge (effect size = 0.73, P = .003), psychological financial hardship (effect size = 0.64, P < .006), and health insurance satisfaction (effect size = 0.55, P = .03). CONCLUSION Results support the feasibility and acceptability of a virtual health insurance navigation program targeted for childhood survivors to improve HIL. Randomized trials to assess the efficacy and sustainability of health insurance navigation on HIL and financial burden are needed.
Increase in the count rates of ground-based cosmic-ray detectors caused by the heliomagnetic disturbance on 5 November 2023
Authors: Chilingarian A. , Karapetyan T. , Sargsyan B. , Zazyan M. , Knapp J. , Walter M. , Rehm T. 
Published: March 2024

Abstract
This letter presents a rare physical phenomenon associated with solar activity, manifesting in anomalies within neutron, electron, and gamma-ray fluxes in the atmosphere. Conventionally, the Earth's magnetic-field disturbances reduce cosmic-ray intensity reaching the surface. However, a temporary surge in cosmic-ray flux occurs intermittently known as the magnetospheric effect (ME). Our observations reveal that this effect predominantly induces a count rate increase in particle detectors positioned at middle latitudes on mountaintops. On November 5, 2023, a 2–3% increase in neutron monitors at mountain altitudes and up to 5% increase in thin plastic scintillators registering electrons and gamma rays was observed. This flux escalation coincided with a southward orientation of the interplanetary magnetic field. Importantly, we present, for the first time, the energy spectrum of the Magnetospheric Effect observed at two mountaintops: Aragats and Zugspitze. Simulations of low-energy proton interactions in the terrestrial atmosphere affirm the augmentation of low-energy cosmic rays. Protons, typically restricted by the geomagnetic cutoff, reached the Earth's atmosphere, generating detectable particle showers on the Earth's surface. To sum up, 1) we measure an increase in the count rate of magnetospheric origin using particle detectors located at mountain altitudes and middle latitudes; 2) for the first time, we measured the energy spectra of the particle fluxes during the magnetospheric effect with spectrometers located on Mount Aragats and Zugspitze; 3) particle flux enhancement coincides with the depletion of the horizontal component of the geomagnetic field; 4) we explain why the magnetospheric effect was observed at mountain altitudes and not at sea level.
MODY Probability Calculator Is Suitable for MODY Screening in China: A Population-based Study
Authors: Zhao Jing , Chen Yan , Ma Fuhui , Shu Hua , Zheng Li , Liu Yang , Li Xia , Xu Tao , Zhou Zhiguang , Zhou Kaixin 
Published: March 2024

AbstractContextSelecting appropriate individuals for genetic testing is essential due to the optimal treatment for maturity-onset diabetes of the young (MODY). However, how to effectively screen for MODY in China remains unclear.ObjectiveTo validate the performance of current screening strategies in selecting patients with MODY based on a nationwide type 2 diabetes cohort.MethodsA panel of 14 MODY genes was analyzed from 1911 type 2 diabetes patients who were ages 15 to 35 years. Variants were evaluated according to the American College of Medical Genetics and Genomics guidelines. Based on this cohort, we simulated the 2 most frequently used screening strategies, including the traditional MODY criteria and the MODY probability calculator (MPC), to assess their ability to select patients with MODY.ResultsFrom a total of 1911 participants, 42 participants harbored pathogenic/likely pathogenic variants. The performance of the traditional criteria was sensitivity: 19.0%, specificity: 72.9%, positive predictive value (PPV): 1.6%, and missing rate: 81.0%. The optimal cut-off for MPC was 40.7%. Based on this cut-off value, the performance was sensitivity: 54.8%, specificity: 81.0%, PPV: 6.1%, and missing rate: 45.2%. Moreover, hemoglobin A1c, insulin treatment, and family history of diabetes have poor discrimination between MODY and young-onset type 2 diabetes.ConclusionThe MPC is better than traditional criteria in terms of both sensitivity and PPV. To ensure more MODY patients benefit from optimal treatment, we therefore suggest that routine genetic testing be performed on all type 2 diabetes patients who are between the ages of 15 and35 years and have MPC probability value over 40.7%.
Reduction of cortical pulling at mitotic entry facilitates aster centration
Authors: Rosfelter Anne , de Labbey Ghislain , Chenevert Janet , Dumollard Rémi , Schaub Sebastien , Machaty Zoltan , Besnardeau Lydia , Gonzalez Suarez Daniel , Hebras Céline , Turlier Hervé , Burgess David R. , McDougall Alex 
Published: March 2024

ABSTRACT
Equal cell division relies upon astral microtubule-based centering mechanisms, yet how the interplay between mitotic entry, cortical force generation and long astral microtubules leads to symmetric cell division is not resolved. We report that a cortically located sperm aster displaying long astral microtubules that penetrate the whole zygote does not undergo centration until mitotic entry. At mitotic entry, we find that microtubule-based cortical pulling is lost. Quantitative measurements of cortical pulling and cytoplasmic pulling together with physical simulations suggested that a wavelike loss of cortical pulling at mitotic entry leads to aster centration based on cytoplasmic pulling. Cortical actin is lost from the cortex at mitotic entry coincident with a fall in cortical tension from ∼300pN/µm to ∼100pN/µm. Following the loss of cortical force generators at mitotic entry, long microtubule-based cytoplasmic pulling is sufficient to displace the aster towards the cell center. These data reveal how mitotic aster centration is coordinated with mitotic entry in chordate zygotes.
A Dual Bounding Framework Through Cost Splitting for Binary Quadratic Optimization
Authors: Bayani Mahdis , Rostami Borzou , Adulyasak Yossiri , Rousseau Louis-Martin 
Published: March 2024

Binary quadratic programming (BQP) is a class of combinatorial optimization problems comprising binary variables, quadratic objective functions, and linear/nonlinear constraints. This paper examines a unified framework to reformulate a BQP problem with linear constraints to a new BQP with an exponential number of variables defined on a graph. This framework relies on the concept of stars in the graph to split the quadratic costs into adjacent and nonadjacent components indicating in-star and out-of-star interactions. We exploit the star-based structure of the new reformulation to develop a decomposition-based column generation algorithm. In our computational experiments, we evaluate the performance of our methodology on different applications with different quadratic structures. The quadratic component of the problem is dealt with in the column generation master problem and its subproblem. Results indicate the superiority of the framework over one of the state-of-the-art solvers, GUROBI, when applied to various benchmark reformulations with adjacent-only or sparse quadratic cost matrices. The framework outperforms GUROBI in terms of both dual bound and computational time in almost all instances. History: Accepted by Andrea Lodi, Area Editor for Design & Analysis of Algorithms—Discrete. Funding: The authors thank the Mitacs Accelerate Program for providing funding for this project. In addition, B. Rostami gratefully acknowledges the funding provided by the Canadian Natural Sciences and Engineering Research Council (NSERC) under a Discovery Grant [Grant RGPIN-2020-05395]. Supplemental Material: The online appendix is available at https://doi.org/10.1287/ijoc.2021.0186 .
Convergence and Stability of Coupled Belief-Strategy Learning Dynamics in Continuous Games
Authors: Wu Manxi , Amin Saurabh , Ozdaglar Asuman 
Published: March 2024

We propose a learning dynamics to model how strategic agents repeatedly play a continuous game while relying on an information platform to learn an unknown payoff-relevant parameter. In each time step, the platform updates a belief estimate of the parameter based on players’ strategies and realized payoffs using Bayes’ rule. Then, players adopt a generic learning rule to adjust their strategies based on the updated belief. We present results on the convergence of beliefs and strategies and the properties of convergent fixed points of the dynamics. We obtain sufficient and necessary conditions for the existence of globally stable fixed points. We also provide sufficient conditions for the local stability of fixed points. These results provide an approach to analyzing the long-term outcomes that arise from the interplay between Bayesian belief learning and strategy learning in games and enable us to characterize conditions under which learning leads to a complete information equilibrium. Funding: Financial support from the Air Force Office of Scientific Research [Project Building Attack Resilience into Complex Networks], the Simons Institute [research fellowship], and a Michael Hammer Fellowship is gratefully acknowledged.
Collaborative Vehicle-to-Grid Operations in Frequency Regulation Markets
Authors: Mak Ho-Yin , Tang Runyu 
Published: March 2024

Problem definition: We study the operations of electric vehicles (EVs) providing frequency regulation services to the electric grid in vehicle-to-grid (V2G) systems. In particular, individually owned EVs collaboratively bid in the regulation market, coordinated by a platform that operates the network of charging equipment. We study how the platform determines optimal pricing incentives for drivers to plug in their EVs, accounting for heterogeneous driving schedules. Methodology/results: We model the platform’s pricing optimization problem as a bilevel program: At the upper level, the platform determines hourly rebates for EV owners to plug in their EVs and capacity bids in the regulation market; at the lower level, individual travelers optimize their travel and charging schedules in response to pricing incentives. To account for uncertainties and heterogeneity in regulation market prices and travel patterns, we adopt distributionally robust optimization techniques to formulate the problem as a mixed-integer second-order cone program. We conduct a computational study based on the California Household Travel Survey data set and actual frequency regulation prices. Our results show that the ability to offer time-varying rebates and install workplace chargers can significantly improve the V2G platform’s expected profits. Managerial implications: As EV adoption progresses past the nascent stage, V2G business models become more viable. Successful implementation of V2G provides economic incentive for switching to EVs, potentially helps sustain adoption growth, and complements the growth of renewable power by helping stabilize the grid. Our findings shed light on the design of driver incentives for V2G systems. Funding: R. Tang acknowledges support from the National Natural Science Foundation of China [Grant 72201206]. Supplemental Material: The online appendices are available at https://doi.org/10.1287/msom.2022.0133 .
Quantile Optimization via Multiple-Timescale Local Search for Black-Box Functions
Authors: Hu Jiaqiao , Song Meichen , Fu Michael C. 
Published: March 2024

Black-Box Quantile Optimization via Finite-Difference-Based Gradient Approximation Risk management necessitates consideration of metrics such as quantiles to supplement conventional mean performance measures. In “Quantile Optimization via Multiple-Timescale Local Search for Black-Box Functions,” J. Hu, M. Song, and M. C. Fu consider the problem where the goal is to optimize the quantile of a black-box output. They introduce two new iterative multitimescale stochastic approximation algorithms utilizing finite-difference-based gradient estimators. The first algorithm requires 2d + 1 samples of the black-box function per iteration, where d is the number of decision variables. The second employs a simultaneous-perturbation-based gradient estimator that uses only three samples per iteration, irrespective of the number of decision variables. The authors prove strong local convergence for both algorithms and analyze their finite-time convergence rates through a novel fixed-point argument. These algorithms perform well across a varied set of benchmark problems.
Pott’s puffy tumour: a rare complication of sinusitis
Authors: Maenhout Marine , Gudelj Maxime , Gilbert Allison 
Published: March 2024

Introduction: Pott’s puffy tumour is a rare entity defined by the presence of a subperiosteal abscess of the frontal bone associated with frontal osteomyelitis. Several predisposing conditions can lead to this entity, such as frontal sinusitis. Case description: We report the case of a 15-year-old patient who presented to the emergency department for headache, fever and forehead swelling. Computed tomography revealed severe pansinusitis complicated by a subperiosteal abscess associated with frontal osteomyelitis, leading to the diagnosis of Pott’s puffy tumour. The management combined intravenous antibiotics and surgical drainage of both the sinusitis and subperiosteal abscess. Discussion: Pott’s puffy tumour represents a rare but serious complication of frontal sinusitis. Clinicians should be aware of this potential complication as the diagnosis can be challenging at an early stage but may influence the subsequent prognosis.
Haematogenous pneumonia caused by Kocuria kristinae in a patient with a central venous catheter
Authors: Natale Raffaele , Nasti Clelia , Morena Annadora , Pasanisi Fabrizio , Santarpia Lidia 
Published: March 2024

Kocuria kristinae is a Gram-positive commensal bacterium, rarely responsible for infection in immunocompromised patients. A 29-year-old woman affected by intestinal pseudo-obstruction and requiring home parenteral nutrition, was hospitalised for fever and shivering during the infusion through a long-term central venous catheter (CVC). Blood cultures were positive for K. kristinae infection. At a chest CT scan, two partially cavitated nodular lesions were evidenced. Meropenem antibiotic therapy was used locally and systemically, resulting in catheter use restoration. A chest CT scan two months later at follow-up showed two centimetric, fibrotic and disventilatory areas replacing the previous nodular thickenings. Kokuria kristinae was responsible for haematogenous pulmonary involvement with excavated nodules, requiring a differential diagnosis. Moreover, in the case of a CVC infection, in addition to the risk of right endocarditis, haematogenous pneumonia must also be considered.
Tm,Ho:YLF waveguide lasers at 2.05 µm
Authors: Bai Zichen , Chen Zhixiang , Xiong Yujie , Liu Hongliang , Gao Siying , Ren Yingying , Zhao Xingjuan , Liu Fengqin , Jia Yuechen , Chen Feng 
Published: March 2024

In this work, we report on the first, to our knowledge, 2.05-µm laser based on femtosecond-laser direct written (FsLDW) Tm,Ho:YLF cladding waveguides. A channel waveguide with a 90-µm diameter “fiber-like” low-index cladding is fabricated in a 6 at. % Tm3+, 0.4 at. % Ho3+:LiYF4 crystal by FsLDW. Pumped by Ti:sapphire laser at 795.1 nm, the fabricated waveguide supports efficient lasing oscillation at 2050 nm with a maximum output power of 47.5 mW, a minimum lasing threshold of 181 mW, and a slope efficiency of 20.1%. The impacts of cavity conditions and polarizations of the pump light on the obtained lasing performance are well studied. The experimental results obtained in this study demonstrate the great potential of utilizing Tm,Ho:YLF and FsLDW for the development of durable mid-infrared lasers featuring compact designs.
Overweight in childhood and consumer purchases in a Danish cohort
Authors: Sørensen Kathrine Kold , Andersen Mikkel Porsborg , Møller Frederik Trier , Wiingreen Rikke , Broccia Marcella , Fosbøl Emil L. , Zareini Bochra , Gerds Thomas Alexander , Torp-Pedersen Christian 
Published: March 2024

Background
Prevention and management of childhood overweight involves the entire family. We aimed to investigate purchase patterns in households with at least one member with overweight in childhood by describing expenditure on different food groups.

Methods
This Danish register-based cohort study included households where at least one member donated receipts concerning consumers purchases in 2019–2021 and at least one member had their Body mass index (BMI) measured in childhood within ten years prior to first purchase. A probability index model was used to evaluate differences in proportion expenditure spent on specific food groups.

Results
We identified 737 households that included a member who had a BMI measurement in childhood, 220 with overweight and 517 with underweight or normal weight (reference households). Adjusting for education, income, family type, and urbanization, households with a member who had a BMI classified as overweight in childhood had statistically significant higher probability of spending a larger proportion of expenditure on ready meals 56.29% (95% CI: 51.70;60.78) and sugary drinks 55.98% (95% CI: 51.63;60.23). Conversely, they had a statistically significant lower probability of spending a larger proportion expenditure on vegetables 38.44% (95% CI: 34.09;42.99), compared to the reference households.

Conclusion
Households with a member with BMI classified as overweight in childhood spent more on unhealthy foods and less on vegetables, compared to the reference households. This study highlights the need for household/family-oriented nutrition education and intervention.
SARS-CoV2 evokes structural brain changes resulting in declined executive function
Authors: Deuter Daniel , Hense Katharina , Kunkel Kevin , Vollmayr Johanna , Schachinger Sebastian , Wendl Christina , Schicho Andreas , Fellner Claudia , Salzberger Bernd , Hitzenbichler Florian , Zeller Judith , Vielsmeier Veronika , Dodoo-Schittko Frank , Schmidt Nils Ole , Rosengarth Katharina 
Published: March 2024

BackgroundSeveral research has underlined the multi-system character of COVID-19. Though effects on the Central Nervous System are mainly discussed as disease-specific affections due to the virus’ neurotropism, no comprehensive disease model of COVID-19 exists on a neurofunctional base by now. We aimed to investigate neuroplastic grey- and white matter changes related to COVID-19 and to link these changes to neurocognitive testings leading towards a multi-dimensional disease model.MethodsGroups of acutely ill COVID-19 patients (n = 16), recovered COVID-19 patients (n = 21) and healthy controls (n = 13) were prospectively included into this study. MR-imaging included T1-weighted sequences for analysis of grey matter using voxel-based morphometry and diffusion-weighted sequences to investigate white matter tracts using probabilistic tractography. Comprehensive neurocognitive testing for verbal and non-verbal domains was performed.ResultsAlterations strongly focused on grey matter of the frontal—basal ganglia—thalamus network and temporal areas, as well as fiber tracts connecting these areas. In acute COVID-19 patients, a decline of grey matter volume was found with an accompanying diminution of white matter tracts. A decline in executive function and especially verbal fluency was found in acute patients, partially persisting in recovered.ConclusionChanges in gray matter volume and white matter tracts included mainly areas involved in networks of executive control and language. Deeper understanding of these alterations is necessary especially with respect to long-term impairments, often referred to as ‘Post-COVID’.
A Rare Case of Emphysematous Gastritis Secondary to Organo-Axial Gastric Volvulus Associated With Sarcina ventriculi
Authors: Rozenberg Jonathan , Mir Adil , Mönkemüller Klaus , Collier Bryan , Grider Douglas 
Published: March 2024

ABSTRACT
Gastric volvulus is a potentially life-threatening condition that can compromise the blood supply to the stomach predisposing to ischemia, eventually necrosis and cell death associated with gas-forming bacteria. Sarcina ventriculi has been associated with emphysematous gastritis also. We report a case of emphysematous gastritis associated with S. ventriculi in the setting of organo-axial gastric volvulus.