bluuebunny/crossref_metadata_2025_split huggingface dataset:
From developmentalism to developmentality: How development constructs its geographies of control and contempt
Authors: Waheed Arslan 
Published: February 2025

AbstractDevelopment is not a set of performative actions. Rather, it is produced and reproduced over the years as a discourse (in the Foucauldian sense) that operates through a variety of categories of knowledge. In this way, development is a set of socio‐political and economic beliefs—an undeniable truth—that is exported to Pakistan through international institutions and technocrats. This paper attempts to understand the dissemination of development in Pakistan by focusing on the constructivist tendencies of development that employ various discursive strategies and language techniques to naturalize the socio‐economic and political hierarchies both socially and spatially. Taking the planning and development of Islamabad—a model urban settlement and a crown jewel of development in the country's history—as the case study, this research finds that various labels, linguistics contrasts, othering, and socio‐economic hierarchies were constructed and employed to construct the socio‐materiality of development as a natural order of things. This developmentality (drawing on Foucault's governmentality) is found in more than 150 planning and policy‐related documents from 1957 to 2018, showing the patronization and reproduction of power hierarchies, inequalities, exclusion, discrimination, and control.
Two Gaps in Studying High‐Fidelity Imitation Across Diverse Childhood Ecologies
Authors: Fong Frankie T. K. , Haun Daniel B. M. 
Published: February 2025

ABSTRACTRecent empirical investigations have concentrated primarily on studying imitation as a social tool that satisfies social motivations, while other potential reasons for and forms of imitation have attracted less attention. These investigations have also focused on studying the role of pedagogy in imitative learning and set up most experiments in a pedagogical framework. In this article, we present two gaps in studying high‐fidelity imitation. First, social motivation may not be the only motivation, especially in less socially stratified communities. Second, imitative learning in observational contexts is understudied. We discuss these gaps by providing examples of alternative imitative learning scenarios and aspects that may have been overlooked and thus underexplored. Moving forward, cross‐cultural investigations targeting other aspects and forms of imitative learning can provide insights into how observational and pedagogical learning together foster effective learning across diverse childhood ecologies.
Seasonal Variation in HLA‐B27 Associated Uveitis
Authors: Samalia Priya D. , Brodie James , Sims Joanne L. , Niederer Rachael L. 
Published: February 2025

ABSTRACTBackgroundTo examine if there was a monthly variation in HLA‐B27‐associated uveitis.MethodsRetrospective review of all individuals presenting to a single centre with HLA‐B27‐associated uveitis from 2009 to 2020.Results577 participants with HLA‐B27‐associated uveitis were included. The median age at presentation was 40.4 years (IQR 31.1–51.4) and 356 (61.7%) were male. 141 (24.4%) participants were diagnosed with ankylosing spondylitis. The incidence of HLA‐B27 uveitis was greatest in August (winter) and lowest in March (autumn). On univariate analysis, there was an inverse relationship between HLA‐B27‐associated uveitis incidence and mean air temperature (β−2.704, p < 0.001) and sunlight hours (β−0.221, p = 0.003), and a positive relationship between uveitis incidence and rainfall (β 0.324, p = 0.006) and humidity (β 1.741, p = 0.006). On multivariate analysis, there was an inverse relationship with temperature (β−4.846, p = 0.002) and a positive association with humidity (β 2.033, p = 0.008). On multivariate analysis, the impact of rainfall shifted to negative (β−0.446, p = 0.017) and sunlight hours lost significance. The monthly effect was more pronounced for non‐Caucasian ethnicities and for those without ankylosing spondylitis.ConclusionIn New Zealand, HLA‐B27‐associated uveitis episodes are influenced by monthly changes with higher incidence in winter months.
Combined Effect of Abutment Height and Restoration Emergence Angle on Peri‐Implant Bone Loss Progression: A Retrospective Analysis
Authors: Misch Jonathan , Abu‐Reyal Sawsan , Lohana Danyal , Mandil Obada , Saleh Muhammad H. A. , Li Junying , Wang Hom‐Lay , Ravidà Andrea 
Published: February 2025

ABSTRACTIntroductionThis study aimed to investigate the combined effect of trans‐mucosal abutment height (TmAH) and restorative emergence angle (REA) on marginal bone loss (MBL) around bone‐level implants.MethodsImplant radiographs 12–18 months after crown placement (T0) and at least one year later (T1) were retrospectively analyzed. Sites were separated into four groups: Long/Narrow‐Angle (LN) with TmAH > 2 mm and REA < 30°, Long/Wide‐Angle (LW) with TmAH > 2 mm and REA ≥ 30°, Short/Narrow‐Angle (SN) with TmAH < 2 mm and REA < 30°, and Short/Wide‐Angle (SW) with TmAH < 2 mm and REA ≥ 30°. MBL was calculated, and multiple linear regression analysis was performed to control for patient‐level and implant/prosthesis‐level factors.Results192 implants pertaining to 119 patients were included. Group significantly influenced MBL experience (p < 0.001). Group SW experienced on average 0.48 mm (95% CI: 0.25–0.71, p < 0.001), 0.43 mm (95% CI: 0.18–0.68, p = 0.001), and 0.25 mm (95% CI: 0.00–0.45, p = 0.013) greater MBL compared to Groups LN, LW, and SN, respectively. Group was also a significant factor impacting the development of peri‐implantitis (p = 0.041), with Group SW displaying a roughly 4× greater likelihood of having peri‐implantitis (PI) diagnosed compared to Groups LN (OR: 4.04; p = 0.091) and LW (OR: 4.19; p = 0.013). Every 1 mm increase in TmAH significantly decreased the likelihood of MBL > 0 mm (OR = 0.63; p = 0.003).ConclusionsAbutment height > 2 mm may play a role in reducing PI and MBL related to ≥ 30° REA around bone‐level implants. REA was found to only be a significant factor when TmAH is less than 2 mm.
Diagnostic accuracy of quantitative faecal immunochemical test in symptomatic patients for the investigation of colorectal cancer once accounting for anaemia severity and iron deficiency
Authors: Lucocq James , Barron Emma , Holmes Heather , Donnelly Peter D. , Cruickshank Neil 
Published: February 2025

AbstractAimThe aim of this study was to determine the diagnostic accuracy of the faecal immunochemical test (FIT) for colorectal cancer (CRC) in symptomatic patients with different levels of anaemia severity or the presence of iron deficiency.MethodSymptomatic patients (2018–2021) from primary care were followed up prospectively for CRC for 2 years. The positive predictive values (PPV) for CRC of FIT subgroups were compared between anaemia severity groups and iron deficiency groups once stratified for symptom type and demographics. The diagnostic accuracy of FIT for CRC was investigated for different definitions of iron deficiency anaemia (IDA).ResultsA total of 17 538 symptomatic patients were investigated, including 310 with CRC (1.8%). In FIT < 100 μg haemoglobin (Hb)/g subgroups, the PPV for CRC was unchanged between anaemia severity levels (p > 0.05). In groups with FIT < 100 μg Hb/g, the PPV for CRC was unchanged in the presence of IDA, non‐iron‐deficiency anaemia and iron deficiency without anaemia (p > 0.05). In the anaemia and IDA subgroups investigated, FIT 10–19 μg Hb/g had a PPV of <3% for CRC and increasing the FIT cut‐off to 20 μg Hb/g could have hypothetically saved 28.6% of colonoscopies. Including transferrin saturation in the definition of IDA increased the detection of CRC in FIT‐negative patients (sensitivity 9.1% vs. 3.9%) but with a low CRC pick‐up rate (PPV = 0.6%; 165 colonoscopies per CRC). Investigating FIT‐negative functional IDA would increase the detection of CRC by 1.3% but with a PPV of 0.5%.ConclusionThe diagnostic accuracy of FIT is excellent regardless of the severity of anaemia, iron deficiency, symptom type or demographics. The FIT cut‐off can be increased safely to 20 μg Hb/g irrespective of anaemia severity or iron deficiency. Altering the definition of IDA does not pragmatically increase the detection of CRC in negative/low FIT patients.
Personalized Recommendation Method Based on Rating Matrix and Review Text
Authors: Wang Shiru , Du Wenna , Bhuiyan Amran , Chen Zehua 
Published: February 2025

ABSTRACTIn recent years, the algorithm based on review text has been widely used in recommendation systems, which can help mitigate the effect of sparsity in rating data within recommender algorithms. Existing methods typically employ a uniform model for capturing user and item features, but they are limited to the shallow feature level, and the user's personalized preferences and deep features of the item have not been fully explored, which may affect the relationship between the two representations learned by the model. The deeper relationship between them will affect the prediction results. Consequently, we propose a personalized recommendation method based on the rating matrix and review text denoted PRM‐RR, which is used to deeply mine user preferences and item characteristics. In the process of processing the comment text, we employ ALBERT to obtain vector representations for the words present in the review text firstly. Subsequently, taking into account that significant words and reviews bear relevance not solely to the review text but also to the user's individualized preferences, the proposed personalized attention module synergizes the user's personalized preference information with the review text vector, thereby engendering an enriched review‐based user representation. The fusion of the user's review representation and rating representation is accomplished through the feature fusion module using cross‐modal attention, yielding the final user representation. Lastly, we employ a factorization machine to predict the user's rating for the item, thereby facilitating the recommendation process. Experimental results on three benchmark datasets show that our method outperforms the baseline algorithm in all cases, demonstrating that our method effectively improves the performance of recommendations. The code is available at https://github.com/ZehuaChenLab/PRM‐RR.
Deep Learning and X‐Ray Imaging Innovations for Pneumonia Infection Diagnosis: Introducing DeepPneuNet
Authors: Chakraborty Sanjay , Nag Tirthajyoti , Pandey Saroj Kumar , Ghosh Jayasree , Dey Lopamudra 
Published: February 2025

ABSTRACTThis paper aims to develop a new deep learning model (DeepPneuNet) and evaluate its performance in predicting Pneumonia infection diagnosis based on patients' chest x‐ray images. We have collected 5856 chest x‐ray images that are labeled as either “pneumonia” or “normal” from a public forum. Before applying the DeepPneuNet model, a necessary feature extraction and feature mapping have been done on the input images. Conv2D layers with a 1 × 1 kernel size are followed by ReLU activation functions to make up the model. These layers are in charge of recognizing important patterns and features in the images. A MaxPooling 2D procedure is applied to minimize the spatial size of the feature maps after every two Conv2D layers. The sparse categorical cross‐entropy loss function trains the model, and the Adam optimizer with a learning rate of 0.001 is used to optimize it. The DeepPneuNet provides 90.12% accuracy for diagnosis of the Pneumonia infection for a set of real‐life test images. With 9,445,586 parameters, the DeepPneuNet model exhibits excellent parameter efficiency. DeepPneuNet is a more lightweight and computationally efficient alternative when compared to the other pre‐trained models. We have compared accuracies for predicting Pneumonia diagnosis of our proposed DeepPneuNet model with some state‐of‐the‐art deep learning models. The proposed DeepPneuNet model is more advantageous than the existing state‐of‐the‐art learning models for Pneumonia diagnosis with respect to accuracy, precision, recall, F‐score, training parameters, and training execution time.
Food Insecurity Is Associated With Current Asthma, Wheeze, and Lung Function in Children and Adults
Authors: Kong Weiliang , Xie Yilian , Xiong Kunlong , Hu Jingjing , Huang Weina , Cao Chao 
Published: February 2025

ABSTRACTBackgroundFood insecurity (FI) has been a global threat, as a social determinant in connection with the prevalence of diseases requiring dietary interventions, such as asthma, has been established. This study aims to examine the relationship between FI and respiratory health outcomes.MethodsThis cross‐sectional study included 7626 children and 17 530 adults from the 2007 to 2012 National Health and Nutritional Examination Surveys (NHANES) in the United States. Weighted multivariate regression models were used to evaluate the associations between FI and respiratory outcomes, including current asthma, wheezing, fractional exhaled nitric oxide (FeNO), and lung function.ResultsThe weighted prevalence of high FI was 19.68% in children and 13.74% in adults. In adults, high FI was significantly associated with current asthma (OR: 1.41, 95% CI: 1.19–1.67) and wheezing (OR: 1.72, 95% CI: 1.48–1.99). The association with asthma was stronger in women (p for interaction = 0.02) and non‐Hispanic Whites (p for interaction = 0.04), whereas wheezing showed stronger associations in non‐Hispanic Whites (p for interaction = 0.01). High FI was linked to lower percent‐predicted forced expiratory volume in 1 s (FEV1) in children (β: −15.93%, 95% CI: −27.82%, −4.03%) and adults (β: −1.13%, 95% CI: −2.22%, −0.04%) without asthma or wheezing. Additionally, high FI was inversely associated with FeNO in adults with current asthma (β: −3.36, 95% CI: −5.54, −1.17) and wheezing (β: −4.40, 95% CI: −7.79, −1.02).ConclusionsFI is associated with increased asthma and wheezing in adults, particularly among women and non‐Hispanic Whites, and with reduced FEV1 in both adults and children without asthma and wheezing.
A Randomized Hybrid‐Effectiveness Trial Comparing Pharmacogenomics (PGx) to Standard Care: The PGx Applied to Chronic Pain Treatment in Primary Care (PGx‐ACT) Trial
Authors: Smith D. Max , Beyene Rut , Kolm Paul , Young Theresa A. , Zifa Sara , Natividad Victoria , Licata Andrea , Podolsky Robert H. , Moore Troy , Walsh Richard , Deva Shikha , Walker Alexander D. , Jacobs Michael B. , Peshkin Beth N. , Swain Sandra M. 
Published: February 2025

ABSTRACTThis trial aimed to identify the effects of providing pharmacogenomic (PGx) results and recommendations for patients with chronic pain treated in primary care practices compared to standard care. An open‐label, prospective, largely virtual, type‐2 hybrid effectiveness trial randomized participants to PGx or standard care arms. Adults with pain ≥ 3 months who were treated with tramadol, codeine, or hydrocodone enrolled. Alternative analgesics were recommended for CYP2D6 intermediate or poor metabolizers (IM/PMs). Prescribing decisions were at providers' discretion. The trial randomized 253 participants. A modified intent‐to‐treat primary analysis assessed change in pain intensity over 3 months among IM/PMs (PGx: 49; Standard care: 57). The PGx and standard care arms showed no difference in pain intensity change (−0.10 ± 0.63 vs. −0.21 ± 0.75 standard deviation; p = 0.74) or PGx‐aligned care (69% vs. 63%; standardized difference [SD] = 0.13). In IM/PMs, secondary analyses of pain intensity change suggested improvements with PGx‐aligned (n = 70; −0.21 ± 0.70) vs. unaligned care (n = 36; −0.06 ± 0.69) (SD = −0.22), with this difference increasing when examining IM/PMs with an analgesic change (aligned: n = 31, −0.28 ± 0.76; unaligned: n = 36, −0.06 ± 0.69; SD = −0.31). This approach to PGx implementation for chronic pain was not associated with different prescribing (i.e., similar proportions of PGx‐aligned care) or clinical outcomes. Secondary analyses suggest that prescribing aligned with PGx recommendations showed a small improvement in pain intensity. However, the proportion of patients with a clinically meaningful improvement (≥ 30%) in pain intensity was similar. Future efforts should identify effective implementation methods.
Barriers to the use of no and low alcohol products in high‐risk drinkers
Authors: Davies Emma L. , Perman‐Howe Parvati , Seddon Jennifer , Piatkowski Timothy , Puljevic Cheneal , Barratt Monica J. , Winstock Adam R. , Ferris Jason A. 
Published: February 2025

AbstractIntroductionConsuming no or low (NoLo) alcohol products in place of regular strength alcohol products could reduce alcohol‐related harms in high risk drinkers. This study provides a new perspective by exploring beliefs about NoLo products and motives for their use by level of risky drinking using a model of behaviour change.MethodsThe 2022 Global Drug Survey included items on NoLo product use, beliefs, and motives for consuming or not consuming NoLo products. Findings were mapped onto the COM‐B (capability‐opportunity‐motivation) model.ResultsIn a sample of 33,033 respondents (59.5% cis men; 37.3% cis women; 3.2% trans/non‐binary) over half (52.2%) reported NoLo product use in the last 12 months. Recent NoLo use was associated with older age, employment status and more common in respondents who drank alcohol compared to non‐drinkers. High‐risk drinkers were more likely to believe NoLo products could help them to drink less and to avoid embarrassment. However, higher risk drinkers who had never consumed NoLo products were more likely to report that they drank to be intoxicated and believed they would not have a good time if they switched.Discussion and ConclusionsPeople who are drinking for enhancement motives (e.g., for fun, to feel intoxicated) may be less amenable to substituting regular strength alcohol products for NoLo products. NoLo use may help some higher risk drinkers consume less alcohol, and social and motivational factors could be targeted to increase their use. There should be renewed focus on broader intervention strategies, such as creating viable social alternatives to consuming alcohol.
Oscillatory But Not Aperiodic Frontal Brain Activity Predicts the Development of Executive Control From Infancy to Toddlerhood
Authors: Rico‐Picó Josué , Garcia‐de‐Soria Bazan M. del Carmen , Conejero Ángela , Moyano Sebastián , Hoyo Ángela , Ballesteros‐Duperón María de los Ángeles , Holmboe Karla , Rueda M. Rosario 
Published: February 2025

ABSTRACTExecutive control (EC) emerges in the first year of life, with the ability to inhibit prepotent responses (inhibitory control [IC]) and to flexibly readapt (cognitive flexibility [CF]) steadily improving. Simultaneously, electrophysiological brain activity undergoes profound reconfiguration, which has been linked to individual variability in EC. However, most studies exploring this relationship have used relative/absolute power and tasks that combine different executive processes. In addition, brain activity conflates aperiodic and oscillatory activity, which hinders the interpretation of the relationship between power and cognition. In the current study, we used the Early Childhood Inhibitory Touchscreen Task (ECITT) to examine the development of EC skills from 9 to 16 months in a longitudinal sample, and related performance of the task to resting‐state EEG (rs‐EEG) power, separating oscillatory and aperiodic activity. Our results showed improvement in IC but not in CF with age. In addition, alpha and theta oscillatory activity were concurrent (9‐mo.) and longitudinal predictors of CF in toddlerhood, whereas the aperiodic exponent of the EEG signal did not contribute to EC. These findings demonstrate the relevance of oscillatory brain activity for cognitive development and provide an early brain marker for the early development of EC.
Safety and effectiveness of stiripentol in patients with Dravet syndrome: A prospective, 3‐year, postmarketing surveillance study
Authors: Kitamura Yuki , Ohyabu Hiroaki , Miura Tatsuo , Takei‐Masuda Naomi , Matsui Daisuke , Inoue Yushi , Ohtsuka Yoko 
Published: February 2025

AbstractAimTo conduct a postmarketing surveillance study of patients with Dravet syndrome in Japan to investigate the safety and effectiveness of long‐term, real‐world, clinical use of stiripentol (STP).MethodThis prospective study was conducted over 156 weeks in all patients with Dravet syndrome who started STP treatment from its launch in Japan in November 2012 until August 2017. Adverse drug reactions (ADRs) were investigated by degree of seriousness. Effectiveness was determined based on a comprehensive assessment by the physician in charge as well as on the percentage change in the number of seizures from the pretreatment period.ResultsIn total, 520 patients (266 males, 254 females; mean age [SD] 10 years 6 months [9 years 10 months]; age range 0–50 years) were included in the safety analysis set, and 515 patients in the effectiveness analysis set. ADRs occurred in 69.2%, including somnolence, decreased appetite, dizziness, in order of frequency. Twelve deaths occurred, the rate of which was not higher than the reported rates. No new safety concerns were identified. The rate of overall improvement (marked or moderate) after 156 weeks or at treatment discontinuation was 37.7%. Decreases in the number of all seizure types over the long term were confirmed.InterpretationIn real‐world clinical settings, long‐term STP treatment can be safe and effective in patients with Dravet syndrome.
Characterization of the effect of naltrexone/bupropion on body composition
Authors: Tardio Vanessa , Yin Peter , Camacho Fernando , Barakat Maxime , Tsoukas Michael A. 
Published: February 2025

AbstractAimsOral treatment extended‐release naltrexone/bupropion (NB) leads to significant weight loss, but its effect on body composition remains unclear. We investigated changes in body composition with dual‐energy x‐ray absorptiometry after treatment with NB or placebo in a subgroup of participants from a randomized control phase 3 study (COR‐I).Materials and MethodsObserved changes from baseline to week 52 were estimated for total, lean, and fat mass. Changes in body composition were evaluated using linear regression and adjusted for baseline covariates.ResultsThe analysis included 82 participants (placebo, n = 26; NB, n = 56) with comparable baseline characteristics (age, BMI, sex). The NB group experienced a significant −7.8% change of total mass (−12.9% change in fat mass and −4.1% in lean mass), compared with a −2.8% change of total mass (−4.8% change in fat mass and −1.4% in lean mass) in the placebo group. The adjusted changes in lean‐to‐fat mass ratio of 0.069 in the NB group and −0.056 in the placebo group were significantly different (p < 0.05).ConclusionsNB‐induced weight loss is associated with significant reductions in total percent fat mass, increase in total percent lean mass, and change in lean‐to‐fat mass ratio, in comparison to placebo. Larger studies are needed to further elucidate the clinical significance of these changes and impact of a potentially healthier metabolism.