bluuebunny/crossref_metadata_2025_split huggingface dataset:
Long‐term telephone therapy outcomes for breast cancer patients
Authors: Sandgren Ann K. , McCaul Kevin D. 
Published: July 2006

AbstractWe present the results of a breast cancer clinical trial that tested two therapy interventions delivered by telephone. Women (N=218) with Stages I, II, or III breast cancer were randomly assigned to breast cancer health education or emotional expression interventions, or to a standard care control condition. Outcome and process measures were obtained at baseline, 6‐month and 13‐month follow‐ups. Oncology certified nurses conducted the therapies in six, 30‐minute individual phone sessions. Women in the health education condition reported significantly better knowledge and less perceived stress compared to women in the emotional expression and control conditions. No treatment effects, however, were obtained for quality of life or mood, and all women generally improved on these measures over time. Secondary analyses showed that younger women and women with a more advanced stage of breast cancer reported significantly greater avoidant coping. The data show that telephone therapy is a viable delivery modality and that distress improves with time for most women. Overall, this study showed that neither of the two telephone interventions tested had a meaningful effect on quality of life or mood. Copyright © 2006 John Wiley & Sons, Ltd.
Comparison of Predictivities of Log P Calculation Models Based on Experimental Data for 134 Simple Organic Compounds
Authors: Sakuratani Yuki , Kasai Kenji , Noguchi Yoshiyuki , Yamada Jun 
Published: July 2006

AbstractPredictivities of six log P calculation models (CLOGP, KOWWIN, ACD/LOGP, SLOGP, VLOGP and COSMO thermo) are compared using a common experimental dataset, which does not contain any of the compounds used in the training set for the six models. The former three models, which are based on fragment methods, showed better accuracy (r=0.87–0.91) than SLOGP, which is based on the atom contribution method and VLOGP and COSMO thermo, which are property‐based models. The trends of prediction by each model are described based on chemical structure and molecular weight. For all six models, several compounds had a significantly greater calculated log P value than the experimental log P value. It is interesting to note that most of these compounds had ionic moieties.
Recurrence relations for fully correlated Gaussians with odd powers of interparticle coordinates
Authors: Harris Frank E. , Monkhorst Hendrik J. 
Published: July 2006

AbstractIt is shown that the recurrence relations previously derived by the present authors, connecting fully correlated Gaussians to which even powers of the interparticle distances have been appended, are also applicable when these distances appear as odd powers. Implications of this demonstration for the description of electron correlation in few‐body systems are also reviewed. © 2006 Wiley Periodicals, Inc. Int J Quantum Chem, 2006
CCSD(T), W1, and other model chemistry predictions for gas‐phase deprotonation reactions
Authors: Pickard Frank C. , Griffith Daniel R. , Ferrara Skylar J. , Liptak Matthew D. , Kirschner Karl N. , Shields George C. 
Published: July 2006

AbstractA series of CCSD(T) single‐point calculations on MP4(SDQ) geometries and the W1 model chemistry method have been used to calculate ΔH° and ΔG° values for the deprotonation of 17 gas‐phase reactions where the experimental values have reported accuracies within 1 kcal/mol. These values have been compared with previous calculations using the G3 and CBS model chemistries and two DFT methods. The most accurate CCSD(T) method uses the aug‐cc‐pVQZ basis set. Extrapolation of the aug‐cc‐pVTZ and aug‐cc‐pVQZ results yields the most accurate agreement with experiment, with a standard deviation of 0.58 kcal/mol for ΔG° and 0.70 kcal/mol for ΔH°. Standard deviations from experiment for ΔG° and ΔH° for the W1 method are 0.95 and 0.83 kcal/mol, respectively. The G3 and CBS‐APNO results are competitive with W1 and are much less expensive. Any of the model chemistry methods or the CCSD(T)/aug‐cc‐pVQZ method can serve as a valuable check on the accuracy of experimental data reported in the National Institutes of Standards and Technology (NIST) database. © 2006 Wiley Periodicals, Inc. Int J Quantum Chem, 2006
Correlated, relativistic, and basis set limit molecular polarizability calculations to evaluate an augmented effective core potential basis set
Authors: Labello Nicholas P. , Ferreira Antonio M. , Kurtz Henry A. 
Published: July 2006

AbstractInitial investigations have demonstrated that an augmented ECP basis set can be used to calculate valence electronic properties with deviations of less than 1% from all‐electron basis sets. Past work has largely focused on molecules with relatively light atoms (Z<18) examined with time‐dependent Hartree–Fock (TDHF) theory. In this work, the dipole moment and polarizability of a number of well‐studied molecules are examined with HF, MP2, CCSD, and CCSD(T) correlated wave functions. Additionally, systems not as thoroughly studied due to the difficulty of all‐electron calculations when Z=50–85 are included. The SBK ECP basis set, augmented with optimized valence functions, performs well across a broad range of methods, less than 3% different from all electron relativistic and correlated wave functions. Orders of magnitude time savings (101–104) are exchanged for a minimal difference from all‐electron basis sets. © 2006 Wiley Periodicals, Inc. Int J Quantum Chem, 2006
In vacuo isotope coded alkylation technique (IVICAT); an N‐terminal stable isotopic label for quantitative liquid chromatography/mass spectrometry proteomics
Authors: Simons Brigitte L. , Wang Guanghui , Shen Rong‐Fong , Knepper Mark A. 
Published: July 2006

AbstractWe present a new isotopic labeling strategy to modify the N‐terminal amino group of peptides in a quantifiable reaction without the use of expensive reagents or solvents. The In Vacuo Isotope Coded Alkylation Technique (IVICAT) is a methylation reaction, carried out at low pressure (<100 mTorr), that results in a stable quaternary trimethylammonium group, thus adding a permanent positive charge at the N‐terminus of peptides without modifying the ε‐amino groups of lysine. The methylation reaction increases the signal intensity of modified peptides in matrix‐assisted laser desorption/ionization mass spectrometry (MALDI‐MS) and liquid chromatography (LC)/MS and the isotopic peak pair differs by 9 mass units which can be easily resolved by either instrument. N‐terminally trimethylated peptides exhibit collision‐induced dissociation (CID) mass spectra that differ from their unmodified analogues by an enhanced b‐ion series in MS2 spectra due to the fixed positive charge. Using LC/MS/MS with an LTQ mass analyzer for quantification, the experimentally determined ratios of H9‐ to D9‐trimethyl‐labeled peptides of β‐casein provided accurate estimates of the actual ratios with low % error. IVICAT labeling also accurately quantified proteins in rat kidney inner medullary collecting duct cell types, as judged by comparison with relative quantification by subsequent immunoblotting experiments. IVICAT labeling, when used in conjunction with the new proteomics software QUIL, can accurately report relative protein abundances and increase the sequence coverage of proteins of tissue proteomes. Published in 2006 by John Wiley & Sons, Ltd.
Three‐dimensional evaluation of mid‐facial hypoplasia in fetuses with trisomy 21 at 11 + 0 to 13 + 6 weeks of gestation
Authors: Dagklis T. , Borenstein M. , Peralta C. F. A. , Faro C. , Nicolaides K. H. 
Published: July 2006

AbstractObjectiveTo investigate the mid‐facial hypoplasia of fetuses with trisomy 21 at 11 + 0 to 13 + 6 weeks of gestation, by three‐dimensional (3D) evaluation of the maxilla and the nasal bones.MethodsA 3D volume of the fetal head was obtained before fetal karyotyping at 11 + 0 to 13 + 6 (median 12) weeks of gestation in 80 fetuses that were subsequently found to have trisomy 21 and in 862 fetuses subsequently found to be chromosomally normal. The multiplanar mode was used to obtain a sequence of transverse views of the fetal face and to demonstrate the maxilla, the adjacent rami of the mandible and the nasal bones. The maxillary depth, defined as the distance between the alveolus of the maxilla in the midline anteriorly and the midpoint of the line joining the rami posteriorly, was measured. Ossification of the nasal bones was considered to be normal if both bones were more echogenic than the overlying skin.ResultsIn the chromosomally normal group the maxillary depth increased linearly with crown–rump length (CRL) from 3.1 mm at a CRL of 45 mm to 4.8 mm at a CRL of 84 mm, and in the trisomy 21 fetuses the depth was significantly smaller than normal (mean difference = − 0.3 mm, P < 0.001). There was no significant association between the delta maxillary depth and delta nuchal translucency thickness in either the trisomy 21 or the chromosomally normal fetuses. Impaired ossification of the nasal bones was observed in 3.1% of the chromosomally normal fetuses and in 60.0% of those with trisomy 21. The mean maxillary depth was significantly smaller in fetuses demonstrating impaired ossification than in those with normal ossification of the nasal bones (mean difference = −0.2 mm; 95% CI, −0.3 to −0.1, P = 0.001).ConclusionsIn a high proportion of fetuses with trisomy 21 there is sonographic evidence of mid‐facial hypoplasia at 11 + 0 to 13 + 6 weeks of gestation. Copyright © 2006 ISUOG. Published by John Wiley & Sons, Ltd.
Radio frequency identification: technologies, applications, and research issues
Authors: Xiao Yang , Yu Senhua , Wu Kui , Ni Qiang , Janecek Christopher , Nordstad Julia 
Published: July 2006

AbstractA radio frequency identification (RFID) system is a special kind of sensor network to identify an object or a person using radio frequency transmission. A typical RFID system includes transponders (tags) and interrogators (readers): tags are attached to objects/persons, and readers communicate with the tags in their transmission ranges via radio signals. RFID systems have been gaining more and more popularity in areas such as supply chain management, automated identification systems, and any place requiring identifications of products or people. RFID technology is better than barcode in many ways, and may totally replace barcode in the future if certain technologies can be achieved such as low cost and protection of personal privacy. This paper provides a technology survey of RFID systems and various RFID applications. We also discuss five critical research issues: cost control, energy efficiency, privacy issue, multiple readers' interference, and security issue. Copyright © 2006 John Wiley & Sons, Ltd.
A client‐side design and implementation for push to talk over cellular service
Authors: Wu Lin‐Yi , Tsai Meng‐Hsun , Lin Yi‐Bing , Yang Jen‐Shun 
Published: July 2006

AbstractThis paper proposes a client architecture for the push to talk over cellular (PoC) service based on the open mobile alliance (OMA) PoC specifications v1.0 release. We show that most standard VoIP modules can be reused for the PoC client, and the VoIP software can be easily extended to support PoC service. Then we present the detailed message flows between the PoC client and other network entities in the PoC system. A PoC client prototype has been implemented in the Industrial Technology Research Institute (ITRI) and National Chiao‐Tung University (NCTU) Joint Research Center. Copyright © 2006 John Wiley & Sons, Ltd.
Shielding TCP from last hop wireless losses
Authors: Vangala Sarma , Labrador Miguel A. 
Published: July 2006

AbstractThe pervasiveness of the transport control protocol (TCP) and the proliferation of wireless local area networks (WLAN) of the 802.11 type make the topic of TCP performance over last hop wireless networks very relevant. The Snoop protocol, a link layer solution introduced several years ago to improve the performance of TCP in this scenario, has been shown to neglect its benefits to the most widely used TCP version, TCP SACK. In this paper, we introduce the TCP SACK‐Aware Snoop protocol to address this problem. Our results indicate that the TCP SACK‐Aware Snoop protocol improves the performance of TCP SACK by around 30% compared with the original Snoop protocol and by about 8% in an environment where no TCP enhancing mechanism is in place. In addition, we introduce further modifications to the proposed protocol to make its advantages available to any TCP sender. We also show that the mechanism does not introduce unfairness among TCP sources and somewhat protects TCP against UDP traffic. Our results show important throughput improvements to all TCP versions and demonstrate that the TCP SACK‐Aware Snoop protocol shields TCP from last hop wireless losses providing throughtput values very close to the maximum possible. Copyright © 2006 John Wiley & Sons, Ltd.
Polyamine deficiency leads to accumulation of reactive oxygen species in a spe2Δ mutant of Saccharomyces cerevisiae
Authors: Chattopadhyay Manas K. , Tabor Celia White , Tabor Herbert 
Published: July 2006

AbstractWe have previously shown that polyamine‐deficient Saccharomyces cerevisiae are very sensitive to incubation in oxygen. The current studies show that, even under more physiological conditions (i.e. growth in air), polyamine‐deficient cells accumulate reactive oxygen species (ROS). These cells develop an apoptotic phenotype and, after incubation in polyamine‐deficient medium, die. To show a specific effect of polyamines on ROS accumulation, uncomplicated by any effects on growth, spermine was added to spermidine‐deficient spe2Δ fms1Δ cells, since spermine does not affect the growth of this strain. In this strain, spermine addition caused a marked, but not complete, decrease in the accumulation of ROS and a moderate protection against cell death. In other experiments with polyamine‐deficient cells containing plasmids that overexpress superoxide dismutases (SOD1, SOD2), ROS decreased but with only a partial protection against cell death. Polyamine‐deficient cells incubated anaerobically show markedly less cell death. These data show that part of the function of polyamines is protection of the cells from accumulation of ROS. Copyright © 2006 John Wiley & Sons, Ltd.
Self-organization of quantum-dot pairs by high-temperature droplet epitaxy
Authors: Wang Zhiming M. , Holmes Kyland , Mazur Yuriy I. , Ramsey Kimberly A. , Salamo Gregory J. 
Published: July 2006

Abstract
The spontaneously formation of epitaxial GaAs quantum-dot pairs was demonstrated on an AlGaAs surface using Ga droplets as a Ga nano-source. The dot pair formation was attributed to the anisotropy of surface diffusion during high-temperature droplet epitaxy.
Relations between alcohol, violence and victimization in adolescence
Authors: Shepherd J.P. , Sutherland I. , Newcombe R.G. 
Published: July 2006

ABSTRACTBackgroundCompared to links between alcohol and aggression, links between alcohol and vulnerability are poorly understood.ObjectivesTo determine whether there is a significant relationship between vulnerability to physical violence and alcohol consumption in adolescence independent of a relationship between alcohol consumption and violent behaviour.Design, setting, participantsCross‐sectional study of 4187 adolescents aged 11–16 in a stratified sample of 13 English schools.ResultsFighting decreased with age whereas hitting others and being hit increased. Relationships between fighting, hitting others and vulnerability to being hit and frequency of drinking and drunkenness were all highly significant (), and were evident at all ages. The outcome most strongly related to frequency of drunkenness was hitting others (odds ratio (OR) 6.62), followed by being hit (OR 4.01) and fighting (OR 2.10). Alcohol consumption and drunkenness remained significantly and independently associated with vulnerability to being hit after adjusting for violent behaviour as well as age and sex.ConclusionsThese findings indicate an association between alcohol and victimization independent of associations of both with physical aggression. Reducing intoxication may reduce victimisation without necessarily affecting violent behaviour. Violence reduction should focus as much on preventing alcohol misuse among victims or potential victims as among offenders.
Transport barriers with magnetic shear in a tokamak
Authors: EL MOUDEN M. , SAIFAOUI D. , DEZAIRI A. , ZINE B. , EDDAHBY M. 
Published: July 2006

AbstractThe reversed magnetic shear is the most important factor in the study of the plasmas of a tokamak. In this paper we focus our research, as a first stage, on the control of the improved confinement regimes by studying the influence of the reversed shear on its quality in the plasma of a tokamak and especially in reducing the anomalous transport in ITER. Then we study the influence of the perturbation modes on the particle diffusion. At the end, a comparison between simulation results obtained using ITER and TEXT parameters is carried out.
Dispersion in a relativistic degenerate electron gas
Authors: McORIST J. , MELROSE D. B. , WEISE J. I. 
Published: July 2006

AbstractRelativistic effects on dispersion in a degenerate electron gas are discussed by comparing known response functions derived relativistically and non-relativistically. The main distinguishing feature is one-photon pair creation, which leads to logarithmic singularities in the response functions. Dispersion curves for longitudinal waves have a similar tongue-like appearance in the relativistic and non-relativistic case, with the main relativistic effects being on the Fermi speed and the cutoff frequency. For transverse waves the non-relativistic treatment has a non-physical feature near the cutoff frequency for large Fermi momenta, and this is attributed to an incorrect treatment of the electron spin. We find (with two important provisos) that one-photon pair creation is allowed in superdense plasmas, implying relatively strong coupling between transverse waves and pair creation.
Targeted Oxygen Delivery within Hepatic Hollow Fiber Bioreactors via Supplementation of Hemoglobin‐Based Oxygen Carriers
Authors: Sullivan Jesse P. , Palmer Andre F. 
Published: July 2006

AbstractHepatic hollow fiber bioreactors are considered a promising class of bioartificial liver assist device (BLAD). Unfortunately, limited oxygen (O2) transport to hepatocytes within this device hinders further development. Hepatocytes in vivo (in the liver sinusoid) experience a wide range of oxygen tensions (pO2 = 25–70 mmHg), which is important for development of proper differentiated function (zonation). Previously, we observed that bovine red blood cell (bRBC) supplementation of the circulating media stream enhanced oxygenation of cultured C3A hepatoma cells compared to a culture with no O2 carrier (Gordon, J.; Palmer, A. F. Artif. Cells, BloodSubstitutes, Biotechnol. 2006, 33 (3), 297–306). Despite this success, the cells were not exposed to the desired in vivo O2 spectrum (Sullivan, J.; Gordon, J.; Palmer, A. Biotechnol. Bioeng. 2006, 93 (2) 306–317). We hypothesize that altering the kinetics of O2 binding/release to/from hemoglobin‐based O2 carriers (HBOCs) could potentially target O2 delivery to cell cultures. High P50 (low O2 affinity) HBOCs preferentially targeted O2 delivery at high inlet pO2 values. Conversely, low P50 (high O2 affinity) HBOCs targeted O2 delivery at low inlet pO2 values. Additionally, inlet pO2, flow rate, and HBOC concentration were varied to find optimal bioreactor operating conditions. Our results demonstrate that HBOCs can enhance O2 delivery to cultured hepatocytes, while exposing them to in vivo‐like O2 tensions, which is critical to create a fully functional BLAD.
Atorvastatin inhibits inflammatory hypernociception
Authors: Santodomingo‐Garzón T , Cunha T M , Verri W A , Valério D A R , Parada C A , Poole S , Ferreira S H , Cunha F Q 
Published: July 2006

Background and purpose:Atorvastatin is an inhibitor of the enzyme 3‐hydroxyl‐3‐methylglutaryl coenzyme A reductase used to prevent coronary heart disease. We have studied the analgesic effect of atorvastatin in inflammatory models in which a sequential release of mediators (bradykinin, (BK), tumour necrosis factor‐α (TNF‐α), interleukin‐1β (IL‐1β) and the chemokine, KC/CXCL) links the stimulus with release of directly acting hypernociceptive mediators such as prostaglandin E2 (PGE2).Experimental approach:The effects of orally administered atorvastatin on inflammatory mechanical hypernociception in mouse paws were evaluated with an electronic pressure‐meter. Cytokines and PGE2 were measured by ELISA and RIA.Key results:Treatment with atorvastatin for 3 days dose‐dependently reduced hypernociception induced by lipopolysaccharide (LPS) or that following antigen challenge in sensitized animals. Atorvastatin pre‐treatment reduced hypernociception induced by bradykinin and cytokines (TNF‐α, IL‐1β and KC), and the release of IL‐1β and PGE2 in paw skin, induced by lipopolysaccharide. The antinociceptive effect of atorvastatin on LPS‐induced hypernociception was prevented by mevalonate co‐treatment without affecting serum cholesterol levels. Hypernociception induced by PGE2 was inhibited by atorvastatin, suggesting intracellular antinociceptive mechanisms for atorvastatin. The antinociceptive effect of atorvastatin upon LPS‐ or PGE2‐induced hypernociception was prevented by non‐selective inhibitors of nitric oxide synthase (NOS) but not by selective inhibition of inducible NOS or in mice lacking this enzyme.Conclusions and implications:Antinociceptive effects of atorvastatin depend on inhibition of cytokines and prostanoid production and on stimulation of NO production by constitutive NOS. Our study suggests that statins may constitute a novel class of analgesic drugs.British Journal of Pharmacology (2006) 149, 14–22. doi:10.1038/sj.bjp.0706836
Characterization of Arabidopsis thaliana–Fusarium graminearum interactions and identification of variation in resistance among ecotypes
Authors: CHEN XINWEI , STEED ANDREW , HARDEN CLARE , NICHOLSON PAUL 
Published: July 2006

SUMMARY Fusarium graminearum causes fusarium head blight (FHB) of wheat and other cereals. Resistance of wheat to FHB is incomplete and the defence mechanisms involved are poorly understood owing to the complex genome and long life cycle of the host. A robust and reproducible bioassay system was established for the study of interactions between F. graminearum and Arabidopsis by wound inoculation of detached leaves embedded in agar medium. Amendment of the inoculum with deoxynivalenol enhanced symptom development and conidial production. Colonization of leaf tissue was by both inter‐ and intracellular growth and extensive cell death was observed ahead of advancing hyphae indicating the presence of phytotoxic compounds or host‐initiated programmed cell death. Expression of defence response genes associated with jasmonic acid/ethylene and salicylic acid pathways indicated that both pathways were activated in response to F. graminearum with expression of the jasmonic acid/ethylene pathways being more enhanced than that of the salicylic acid pathway, as expected for a necrotrophic pathogen. A large variation in resistance among Arabidopsis ecotypes was revealed. The ecotype Col‐0 was significantly more resistant than Ler using both the detached leaf and a detached flower assay. Foliar resistance was shown to be controlled largely by a single genetic factor on chromosome 4 near the RFLP marker O6455. The detached leaf assay described herein provides a means to enable fundamental studies on the defence mechanisms of Arabidopsis in response to F. graminearum.