bluuebunny/crossref_metadata_2025_split huggingface dataset:
Exploring the characteristics of non-urban coworking spaces in Germany and their perceived benefits for corporate users: novel means for supporting corporate real estate management strategies
Authors: Vogl Thomas , Orel Marko , Appel-Meulenbroek Rianne 
Published: April 2024

PurposeThis study aims to enrich our understanding of the characteristics of non-urban coworking spaces (CSs) that focus on corporate users, as well as the benefits that companies expect to gain from incorporating those CSs into their corporate real estate (CRE) portfolios.Design/methodology/approachThis study leverages a series of in-depth interviews with owners and managers of CSs in non-urban locales that focus on serving corporate clients.FindingsThe research reveals various CS characteristics and forms within non-urban areas, focusing on corporate clients. It suggests that implementing a CS in corporate premises is perceived to enhance CRE use-value strategies with a focus on the employee's well-being, innovation and the attraction of talents. Moreover, exchange-value strategies with a focus on portfolio flexibility may benefit from the implementation of a CS. However, strategies related to life-cycle cost optimization or gains are not perceived to be supported. Social events for the surrounding neighborhood and the choice of location emerge as critical success factors for non-urban CSs. Besides infrastructure and connectivity, non-urban corporate-centric CSs built their location decisions rather on a personal connection to the location and place of residence of potential users than on lower rental prices.Originality/valueThis research pioneers in providing a comprehensive understanding of non-urban CSs, particularly in the context of their perceived implications for corporate real estate management. The nuanced perspectives it offers are invaluable for stakeholders looking to leverage CSs as part of their corporate strategies.
Understanding the behavioural drivers of mindful consumption: a study on the use of sustainable menstrual products
Authors: Lathabhavan Remya , Lathabhavan Revathy 
Published: April 2024

Purpose
The adverse environmental impacts of menstrual products are a significant concern because of their widespread use and non-biodegradability. With various global and regional initiatives on sustainability, there is now greater public awareness about environmental protection. This heightened awareness has resulted in the exploration of alternative methods to reduce waste, such as the development and use of sustainable menstrual products. This study aims to examine the factors that influence Indian women’s purchasing intention in relation to sustainable menstrual products. The study uses the Stimulus–Organism–Behavior–Consequence (SOBC) theory as the appropriate grounded theory to explain these determinants.

Design/methodology/approach
Cross-sectional data were collected from 720 women who have been using sustainable menstrual products. For analysing the model, the study performed structural equation modelling using AMOS.

Findings
The study’s results indicated that health consciousness, sustainability knowledge and environmental responsibility are positively associated with self-identity and mindfulness. Additionally, the study found that organism states have a positive impact on the purchase intention of sustainable menstrual products. Furthermore, there was a significant relationship observed between purchase intention and mindful consumption. The study also discovered significant positive relationships between satisfaction and key associations.

Originality/value
This study may be considered pioneering, as it establishes a connection between the usage of sustainable menstrual products and concepts such as mindfulness and mindful consumption.
Social engineering awareness and resilience in Egypt: a quantitative exploration
Authors: Shehata Ahmed , Eldakar Metwaly 
Published: April 2024

PurposeSocial engineering is crucial in today’s digital landscape. As technology advances, malicious individuals exploit human judgment and trust. This study explores how age, education and occupation affect individuals’ awareness, skills and perceptions of social engineering.Design/methodology/approachA quantitative research approach was used to survey a diverse demographic of Egyptian society. The survey was conducted in February 2023, and the participants were sourced from various Egyptian social media pages covering different topics. The collected data was analyzed using descriptive and inferential statistics, including independent samples t-test and ANOVA, to compare awareness and skills across different groups.FindingsThe study revealed that younger individuals and those with higher education tend to research social engineering more frequently. Males display a higher level of awareness but score lower in terms of social and psychological consequences as well as types of attacks when compared to females. The type of attack cannot be predicted based on age. Higher education is linked to greater awareness and ability to defend against attacks. Different occupations have varying levels of awareness, skills, and psychosocial consequences. The study emphasizes the importance of increasing awareness, education and implementing cybersecurity measures.Originality/valueThis study’s originality lies in its focus on diverse Egyptian demographics, innovative recruitment via social media, comprehensive exploration of variables, statistical rigor, practical insights for cybersecurity education and diversity in educational and occupational backgrounds.
In-situ synthesis of SiO2 aerogel/polyethylene terephthalate composite slices and their fibers
Authors: Yang Fukang , Wang Wenjun , Yan Yongjie , Dong YuBing 
Published: April 2024

Purpose
Polyethylene terephthalate (PET) as a fiber molding polymer is widely used in aerospace, electrical and electronic, clothing and other fields. The purpose of this study is to improve the thermal insulation performance of polyethylene terephthalate (PET), the SiO2 aerogel/PET composites slices and fibers were prepared, and the effects of the SiO2 aerogel on the morphology, structure, crystallization property and thermal conductivity of the SiO2 aerogel/PET composites slices and their fibers were systematically investigated.

Design/methodology/approach
The mass ratio of purified terephthalic acid and ethylene glycol was selected as 1:1.5, which was premixed with Sb2O3 and the corresponding mass of SiO2 aerogel, and SiO2 aerogel/PET composites were prepared by direct esterification and in-situ polymerization. The SiO2 aerogel/PET composite fibers were prepared by melt-spinning method.

Findings
The results showed that the SiO2 aerogel was uniformly dispersed in the PET matrix. The thermal insulation coefficient of PET was significantly reduced by the addition of SiO2 aerogel, and the thermal conductivity of the 1.0 Wt.% SiO2 aerogel/PET composites was reduced by 75.74 mW/(m · K) compared to the pure PET. The thermal conductivity of the 0.8 Wt.% SiO2 aerogel/PET composite fiber was reduced by 46.06% compared to the pure PET fiber. The crystallinity and flame-retardant coefficient of the SiO2 aerogel/PET composite fibers showed an increasing trend with the addition of SiO2 aerogel.

Research limitations/implications
The SiO2 aerogel/PET composite slices and their fibers have good thermal insulation properties and exhibit good potential for application in the field of thermal insulation, such as warm clothes. In today’s society where the energy crisis is becoming increasingly serious, improving the thermal insulation performance of PET to reduce energy loss will be of great significance to alleviate the energy crisis.

Originality/value
In this study, SiO2 aerogel/PET composite slices and their fibers were prepared by an in situ polymerization process, which solved the problem of difficult dispersion of nanoparticles in the matrix and the thermal conductivity of PET significantly reduced.
Towards a sustainable future: a comprehensive review of Green Sukuk
Authors: Alkadi Rotana S. 
Published: April 2024

Purpose
Green sukuk (GS) is an emerging financial tool that has gained momentum in recent years owing to increased attention being given to Islamic finance, socially responsible investing (SRI) and sustainability agendas. Yet, GS studies are fragmented, dispersed and lack comprehensive reviews. As a response to this gap in academia, this paper aims to synthesize the knowledge on GS into thematic clusters, providing a more comprehensive understanding of the subject and offering guidelines for future research.

Design/methodology/approach
This study implemented a systematic literature review approach to analyse studies on GS that were published prior to and including June 2023. The PRISMA 2020 protocol was used in the sample selection process. A total of 62 peer-reviewed journal articles from six databases were identified and categorized into various themes.

Findings
The results suggest that previous research has predominantly focused on the areas of GS advantages, drivers, market development and potential sectors, along with challenges and recommendations to improve the market. However, it was found that some other aspects, including GS pricing, performance and purchasing intention, require further research attention. The analysis also indicated that the use of theories in the GS context was limited, with only five theories employed in just four out of the 62 articles examined. Moreover, this paper’s findings revealed that the studies employing quantitative and empirical analysis methods were limited to four articles. Geographically, most of the studies were conducted in Indonesia and Malaysia, while other countries with high-potential markets (e.g. GCC) had limited GS practices and studies.

Practical implications
The results of this study have several practical implications. For investors, a review of GS will provide greater insight into the understanding of the GS market, helping them make better investment decisions. For policymakers, this paper empowers them with the knowledge to make informed decisions regarding GS markets by highlighting key recommendations identified in the literature. Finally, the proposed guidelines can be used in future research.

Originality/value
While Green Bonds have received significant attention, there is a dearth of research on GS and those that exist are fragmented. A systematic literature review is necessary to identify knowledge gaps for future research.
Microorganisms uniquely capture and predict stony coral tissue loss disease and hurricane disturbance impacts on US Virgin Island reefs
Authors: Becker Cynthia C. , Weber Laura , Llopiz Joel K. , Mooney T. Aran , Apprill Amy 
Published: April 2024

AbstractCoral reef ecosystems are now commonly affected by major climate and disease disturbances. Disturbance impacts are typically recorded using reef benthic cover, but this may be less reflective of other ecosystem processes. To explore the potential for reef water‐based disturbance indicators, we conducted a 7‐year time series on US Virgin Island reefs where we examined benthic cover and reef water nutrients and microorganisms from 2016 to 2022, which included two major disturbances: hurricanes Irma and Maria in 2017 and the stony coral tissue loss disease outbreak starting in 2020. The disease outbreak coincided with the largest changes in the benthic habitat, with increases in the percent cover of turf algae and Ramicrusta, an invasive alga. While sampling timepoint contributed most to changes in reef water nutrient composition and microbial community beta diversity, both disturbances led to increases in ammonium concentration, a mechanism likely contributing to observed microbial community shifts. We identified 10 microbial taxa that were sensitive and predictive of increasing ammonium concentration. This included the decline of the oligotrophic and photoautotrophic Prochlorococcus and the enrichment of heterotrophic taxa. As disturbances impact reefs, the changing nutrient and microbial regimes may foster a type of microbialization, a process that hastens reef degradation.
Outcomes and quality of care for women and their babies after caesarean section in Nigeria
Authors: Adeniran Abiodun S. , Nwachukwu Duum C. , Ocheke Amaka N. , Mohammed Salisu O , Musa Abdulkarim O. , Ochejele Silas , Ibraheem Rais S. , Pam Samuel , Mairami Amsa B. , Gobir Aishatu A. , Olateju Eyinade K. , Baba Fatimah J. , Medupin Patricia F. , Ahmed Grace , Ango Sarah , Akaba Godwin , Ogunkunle Taofik O. , Agada Egwu , Gibbons Luz , Oladapo Olufemi T. , Lavin Tina , Tukur Jamilu , Aboyeji Abiodun P. ,   Maternal and Perinatal Database for Quality, Equity and Dignity Collaborators
Published: April 2024

AbstractObjectiveTo describe the outcomes and quality of care for women and their babies after caesarean section (CS) in Nigerian referral‐level hospitals.DesignSecondary analysis of a nationwide cross‐sectional study.SettingFifty‐four referral‐level hospitals.PopulationAll women giving birth in the participating facilities between 1 September 2019 and 31 August 2020.MethodsData for the women were extracted, including sociodemographic data, clinical information, mode of birth, and maternal and perinatal outcomes. A conceptual hierarchical framework was employed to explore the sociodemographic and clinical factors associated with maternal and perinatal death in women who had an emergency CS.Main Outcome MeasuresOverall CS rate, outcomes for women who had CS, and factors associated with maternal and perinatal mortality.ResultsThe overall CS rate was 33.3% (22 838/68 640). The majority of CS deliveries were emergency cases (62.8%) and 8.1% of CS deliveries had complications after delivery, which were more common after an emergency CS. There were 179 (0.8%) maternal deaths in women who had a CS and 29.6% resulted from complications of hypertensive disorders of pregnancy. The overall maternal mortality rate in women who delivered by CS was 778 per 100 000 live births, whereas the perinatal mortality at birth was 51 per 1000 live births. Factors associated with maternal mortality in women who had an emergency CS were being <20 or >35 years of age, having a lower level of education and being referred from another facility or informal setting.ConclusionsOne‐third of births were delivered via CS (mostly emergency), with almost one in ten women experiencing a complication after a CS. To improve outcomes, hospitals should invest in care and remove obstacles to accessible quality CS services.
Accessory gland protein regulates pairing process and oviposition in the subterranean termite Reticulitermes chinensis after swarming
Authors: Liu Yutong , Zhang Fei , Hassan Ali , Zhou Xuguo , Huang Qiuying 
Published: April 2024

AbstractSwarming and pairing behaviors are significant to population dispersal of termites. Tandem running is a key process in pairing behavior of dealates to find a mate. Succinylation can lead to significant changes in protein structure and function, which is widely involved in metabolism and behavior regulation in many organisms. However, whether succinylation modification regulates termites’ tandem running is currently unknown. In this research, we performed quantitative modified proteomics of the subterranean termite Reticulitermes chinensis Snyder before and after alate swarming. The succinylation levels of accessory gland protein (ACP) were significantly altered after alate swarming. We found that ACP is enriched in male accessory gland and female oocytes of termites. The acetylation and succinylation sites of ACP affected tandem running of dealates. The transcriptome and metabolome analyses of alates injected with ACP and its mutant proteins showed that β‐alanine metabolism pathway was the major downstream pathway of ACP. Silencing the significantly differentially expressed genes in the β‐alanine metabolic pathway (acyl‐CoA dehydrogenase, enoyl‐CoA hydratase, 3‐hydroxyisobutyrate dehydrogenase, methylmalonate‐semialdehyde dehydrogenase) suppressed tandem running and altered oviposition of paired dealates. These findings demonstrate that protein translation modification is an important regulator of tandem running behavior of termites, which implies that the succinylation and acetylation modification sites of ACP could be potential targets for insecticide action. Our research offers a potential approach for developing novel dispersal inhibitors against social insect pests.
Routine biomarker profile for the prediction of clinical phenotypes of adult‐onset Still's disease using unsupervised clustering algorithm
Authors: Gallardo‐Pizarro Antonio , Campos‐Rodríguez Valerio , Martín‐Iglesias Daniel , Ruiz‐Irastorza Guillermo 
Published: April 2024

AbstractAimThis study addresses the challenge of predicting the course of Adult‐onset Still's disease (AoSD), a rare systemic autoinflammatory disorder of unknown origin. Precise prediction is crucial for effective clinical management, especially in the absence of specific laboratory indicators.MethodsWe assessed the effectiveness of combining traditional biomarkers with the k‐medoids unsupervised clustering algorithm in forecasting the various clinical courses of AoSD—monocyclic, polycyclic, or chronic articular. This approach represents an innovative strategy in predicting the disease's course.ResultsThe analysis led to the identification of distinct patient profiles based on accessible biomarkers. Specifically, patients with elevated ferritin levels at diagnosis were more likely to experience a monocyclic disease course, while those with lower erythrocyte sedimentation rate could present with any of the clinical courses, monocyclic, polycyclic, or chronic articular, during follow‐up.ConclusionThe study demonstrates the potential of integrating traditional biomarkers with unsupervised clustering algorithms in understanding the heterogeneity of AoSD. These findings suggest new avenues for developing personalized treatment strategies, though further validation in larger, prospective studies is necessary.
The impact of frailty and rapid response team activation on patients admitted to the intensive care unit: A case‐control matched, observational, single‐centre cohort study
Authors: Dugan Christopher , Weightman Suzanne , Palmer Vanessa , Schulz Luis , Aneman Anders 
Published: April 2024

AbstractBackgroundFrailty is a multi‐dimensional syndrome associated with mortality and adverse outcomes in patients admitted to the intensive care unit (ICU). Further investigation is warranted to explore the interplay among factors such as frailty, clinical deterioration triggering a medical emergency team (MET) review, and outcomes following admission to the ICU.MethodsSingle‐centre, retrospective observational case‐control study of adult patients (>18 years) admitted to a medical‐surgical ICU with (cases) or without (controls) a preceding MET review between 4 h and 14 days prior. Matching was performed for age, ICU admission diagnosis, Acute Physiology and Chronic Health Evaluation III (APACHE III) score and the 8‐point Clinical Frailty Scale (CFS). Cox proportional hazard regression modelling was performed to determine associations with 30‐day mortality after admission to ICU.ResultsA total of 2314 matched admissions were analysed. Compared to non‐frail patients (CFS 1–4), mortality was higher in all frail patients (CFS 5–8), at 31% vs. 13%, and in frail patients admitted after MET review at 33%. After adjusting for age, APACHE, antecedent MET review and CFS in the Cox regression, mortality hazard ratio increased by 26% per CFS point and by 3% per APACHE III point, while a MET review was not an independent predictor. Limitations of medical treatment occurred in 30% of frail patients, either with or without a MET antecedent, and this was five times higher compared to non‐frail patients.ConclusionFrail patients admitted to ICU have a high short‐term mortality. An antecedent MET event was associated with increased mortality but did not independently predict short‐term survival when adjusting for confounding factors. The intrinsic significance of frailty should be primarily considered during MET review of frail patients. This study suggests that routine frailty assessment of hospitalised patients would be helpful to set goals of care when admission to ICU could be considered.
Progeria‐based vascular model identifies networks associated with cardiovascular aging and disease
Authors: Ngubo Mzwanele , Chen Zhaoyi , McDonald Darin , Karimpour Rana , Shrestha Amit , Yockell‐Lelièvre Julien , Laurent Aurélie , Besong Ojong Tabi Ojong , Tsai Eve C. , Dilworth F. Jeffrey , Hendzel Michael J. , Stanford William L. 
Published: April 2024

AbstractHutchinson‐Gilford Progeria syndrome (HGPS) is a lethal premature aging disorder caused by a de novo heterozygous mutation that leads to the accumulation of a splicing isoform of Lamin A termed progerin. Progerin expression deregulates the organization of the nuclear lamina and the epigenetic landscape. Progerin has also been observed to accumulate at low levels during normal aging in cardiovascular cells of adults that do not carry genetic mutations linked with HGPS. Therefore, the molecular mechanisms that lead to vascular dysfunction in HGPS may also play a role in vascular aging‐associated diseases, such as myocardial infarction and stroke. Here, we show that HGPS patient‐derived vascular smooth muscle cells (VSMCs) recapitulate HGPS molecular hallmarks. Transcriptional profiling revealed cardiovascular disease remodeling and reactive oxidative stress response activation in HGPS VSMCs. Proteomic analyses identified abnormal acetylation programs in HGPS VSMC replication fork complexes, resulting in reduced H4K16 acetylation. Analysis of acetylation kinetics revealed both upregulation of K16 deacetylation and downregulation of K16 acetylation. This correlates with abnormal accumulation of error‐prone nonhomologous end joining (NHEJ) repair proteins on newly replicated chromatin. The knockdown of the histone acetyltransferase MOF recapitulates preferential engagement of NHEJ repair activity in control VSMCs. Additionally, we find that primary donor‐derived coronary artery vascular smooth muscle cells from aged individuals show similar defects to HGPS VSMCs, including loss of H4K16 acetylation. Altogether, we provide insight into the molecular mechanisms underlying vascular complications associated with HGPS patients and normative aging.
A novel exosome‐related prognostic risk model for thyroid cancer
Authors: Qi Junfeng , Cheng Hanshan , Su Long , Li Jun , Cheng Fei 
Published: April 2024

AbstractAimThe aim was to build an exosome‐related gene (ERG) risk model for thyroid cancer (TC) patients.MethodsNote that, 510 TC samples from The Cancer Genome Atlas database and 121 ERGs from the ExoBCD database were obtained. Differential gene expression analysis was performed to get ERGs in TC (TERGs). Functional enrichment analyses including Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) were conducted on the TERGs. Then we constructed a model based on LASSO Cox regression analysis. Kaplan‐Meier survival analysis was applied and a Nomogram model was also built. The immune landscape was evaluated by CIBERSORT.ResultsThirty‐eight TERGs were identified and their functions were enriched on 591 GO terms and 30 KEGG pathways. We built a Risk Score model based on FGFR3, ADRA1B, and POSTN. Risk Scores were significantly higher in T4 than in other stages, meanwhile, it didn't significantly differ in genders and TNM N or M classifications. The nomogram model could reliably predict the overall survival of TC patients. The mutation rate of BRAF and expression of cytotoxic T‐lymphocyte‐associated protein 4 were significantly higher in the high‐risk group than in the low‐risk group. The risk score was significantly correlated to the immune landscape.ConclusionWe built a Risk Score model using FGFR3, ADRA1B, and POSTN which could reliably predict the prognosis of TC patients.