bluuebunny/crossref_metadata_2025_split huggingface dataset:
The relationship between cheek tooth occlusal morphology, apparent digestibility, and ingesta particle size reduction in horses
Authors: Carmalt James L. , Allen Andrew 
Published: August 2008

Abstract
Objective—To investigate potential relationships between cheek tooth occlusal morphology, apparent feed digestibility, and the reduction in feed particle size that occurs during digestion in horses.
Design—Cross-sectional study.
Animals—17 horses of various ages and breeds and either sex.
Procedures—Horses were fed 1 of 3 hay-based diets ad libitum for 14 days prior to euthanasia; nutrient analysis was performed on samples of each of the 3 diets. At the time of postmortem examination, the head was disarticulated, photographs were taken of the occlusal surfaces of the maxillary and mandibular cheek tooth arcades, and samples of stomach and small colon or rectum contents were collected for determination of apparent feed digestibility and particle size determination. An overall oral pathology score was assigned, and morphologic features of the occlusal surfaces of the cheek tooth arcades were determined.
Results—Results of nutrient analyses did not differ among the 3 hay diets, and there was no significant difference in apparent feed digestibility among diets. Feed particle size differed significantly among the 3 diets, but stomach content and fecal particle sizes did not differ among diet groups. No significant correlations were identified between cheek tooth morphologic variables and feed digestibility, and fecal particle size was not significantly associated with oral pathology score.
Conclusions and Clinical Relevance—Results did not provide any evidence of associations between cheek tooth morphologic variables, fecal particle size, and apparent digestibility in horses.
Use of intralesional formalin administration for treatment of a subepiglottic cyst in a horse
Authors: Dougherty Sarah S. , Palmer Jan L. 
Published: August 2008

Abstract
Case Description—A 4-year-old horse was evaluated for chronic coughing, mucopurulent nasal discharge, and failure to thrive.
Clinical Findings—Endoscopy was performed on the larynx, pharynx, and trachea and revealed an approximately 2-cm fluctuant subepiglottic cyst.
Treatment and Outcome—The subepiglottic cyst was treated with intralesional formalin administration. Following 2 injections, 2 weeks apart, the cyst was completely resolved with no evidence of scarring or epiglottic deformity.
Clinical Relevance—Findings suggest that intralesional formalin administration for treatment of subepiglottic cysts may be a minimally invasive, economically suitable alternative to surgical treatments.
Changes of microbial indices of water quality in the Vistula and Brda rivers as a result of sewage treatment plant operation
Authors: Walczak Maciej 
Published: August 2008

Abstract
This paper reports the results of studies of microbiological changes in the water quality of the Vistula and Brda rivers after the opening of sewage treatment plants in Bydgoszcz. The study involved determining the microbiological parameters of water quality. Based on the results obtained, it was found that the quality of the water in both rivers had improved decidedly after the opening of the plants, although an increased number of individual groups of microorganisms was found at the treated sewage outlet from one of the plants.
Misidentification and Other Preanalytical Errors
Authors: Bonini Pierangelo , Ceriotti Ferruccio , Mirandola Gaia , Signori Chiara 
Published: August 2008

Misidentification and Other Preanalytical Errors
The largest number of laboratory errors occur in the preanalytical phase and are mainly due to educational and organizational reasons. The experience of our institution, as well as the results of an Italian interlaboratory effort to detect and reduce errors/risk of errors in laboratory medicine will be illustrated.
Improving the Preanalytical Process: The Focus on Specimen Quality
Authors: Green Sol 
Published: August 2008

Improving the Preanalytical Process: The Focus on Specimen Quality
Trends in clinical laboratory practice place more demands on the quality of patient specimens. Advances in analytical performance (i.e., increased automation, reduced sample volume, increased assay sensitivity), as well as efficiency and cost reduction gains (i.e., throughput, test turnaround time) have improved medical practice. These changes, however, have caused an increased incidence of preanalytical errors, dictating the need for higher-quality specimens. The following paper addresses these errors in addition to methodologies for improving the quality of the preanalytical phase.
The Significance of Urinary Markers in the Evaluation of Diabetic Nephropathy
Authors: Cvetković Tatjana , Vlahović Predrag , đorđević Vidosava , Zvezdanović Lilika , Pavlović Dušica , Kocić Gordana , Sokolović Dušan 
Published: August 2008

The Significance of Urinary Markers in the Evaluation of Diabetic Nephropathy
Oxidative stress is considered to be a unifying link between diabetes mellitus (DM) and its complications, including nephropathy (DN). The aim of this study was to determine the parameters of oxidative injury of lipids and proteins as well as the activity of ectoenzymes in the urine of DN patients. The study included 40 individuals: 10 patients with type 2 diabetes mellitus and microalbuminuria (DMT2-MIA), 10 type 2 diabetic patients with macroalbuminuria (DMT2-MAA), 10 patients with type 1 diabetes and microalbuminuria (DMT1-MIA) and 10 age- and sex-matched healthy subjects (control). In the urine we determined TBA reactive substances (TBARS), reactive carbonyl groups (RCG), and the activity of ectoenzymes N-acetyl-β-d-glucosaminidase (NAG), plasma cell differentiation antigen (PC-1), aminopeptidase N (APN) and dipeptidyl peptidase IV (DPP IV). A higher concentration of TBARS in the urine was found in DMT2-MIA and DMT1-MIA, compared to the control group (p<0.001 and P<0.05). The urine concentration of RCD shows similar results with a significant elevation in the groups with DMT2-MAA and DMT1-MIA, compared to the DMT2-MIA (p<0.001) and control group (p<0.001). Activities of NAG, APN and DPPIV were significantly higher in the urine of DMT2-MAA, compared to the control (p<0.01). The activity of PC-1 was slightly increased in that group, but not significantly. In conclusion, the level of oxidative stress markers and activities of brush border ectoenzymes in the urine may be a useful non-invasive and easily repeatable test in DN.
Contemporary diagnostic methods for ship engines: a report on scientific research activity of Polish Naval Academy in this field
Authors: Korczewski Zbigniew 
Published: August 2008

Contemporary diagnostic methods for ship engines: a report on scientific research activity of Polish Naval Academy in this field
This paper devoted to ship combustion engine diagnostics, presents short characteristics of experimental test techniques applicable to state assessment of piston and gas turbine engines presently being in use in Polish Navy. Some metrological and organizational aspects of realization of necessary diagnostic tests as well as measurements of control parameters of engines of low susceptibility to control, were highlighted. Such engines are installed a.o. on board American origin frigates of Oliver Hazard Perry type as well as Norwegian origin submarines of Kobben type which have been recently incorporated into Polish Navy (i.e.General Electric turbine engines, Detroit Diesel and Mercedes Benz piston engines), as well as older engines of Russian production (Zorya turbine engines, Zvezda piston engines). Applicability of particular diagnostic methods was also assessed from the point of view of their effectiveness in identifying engine failures in conditions of its operation in ship power plant. Recently realized tests have made it possible to conduct operation of all piston and turbine engines used on board Polish Navy ships in accordance with their current technical state. On the average 120-130 diagnostic expertises are yearly issued, and the carried-out tests cover main functional systems of engines together with their control and safety subsystems.
Detection of ferromagnetic objects in local magnetic anomaly of the Baltic Sea
Authors: Wołoszyn Mirosław 
Published: August 2008

Detection of ferromagnetic objects in local magnetic anomaly of the Baltic Sea
In geological researches several kinds of methods are applied to discovering the natural resources. Planes, helicopters and UAVs (UnmAnned Vehicle) are used in researches in large areas. The gravity, electromagnetic and magnetic methods, which are used in geological researches, are presented in this paper. The special attention was paid to magnetic systems installed on mobile platforms. The magnetic field of the Earth obtained from mathematical model was compared to the real magnetic field in the selected part of the Baltic Sea. The results of the calculations showed that the mathematical model of the Earth's magnetic field does not consider local magnetic anomalies. The strong local magnetic anomalies cause serious problems with detection of underwater objects. Special problems appear in the magnetic system on a helicopter, which are presented in this paper.
Food industry waste composting in a rotational reactor
Authors: Tronina Przemysław , Bubel Fabiola 
Published: August 2008

Food industry waste composting in a rotational reactor
The permanently rising costs of food industry waste management create a real necessity for searching for new economical and environmentally friendly technologies with which such waste can be utilized. The purpose of this study was an evaluation of waste composting using rotational reactor technology with further use of the resultant product as a fertilizer. In order to conduct the research, a rotational reactor was designed and constructed. For the composting process, such waste materials as meat and bone pulp, past its sell-by date dairy and bakery products, sawdust, poultry and cattle manure, were used. The composition of the composted masses was chosen so that their approximate C:N:P proportions and consistency were appropriate for the growth of biodegradating micro-organisms. The efficiency of the presented technology was evaluated based on the inactivation of selected strains of bacteria and the eggs of invasive parasites. The products obtained were tested by the Institute of Soil Science and Plant Cultivation in Puławy with regard to its possible environmental usage.
Employing Similarity Measures to Examine the Development of Technical Infrastructure in Polish Counties
Authors: Nermend Kesra 
Published: August 2008

Employing Similarity Measures to Examine the Development of Technical Infrastructure in Polish CountiesThe article presents a comparison made with reference to three similarity measures and Minkowski measures, namely urban measure, the Euclidean measure and Chebyshev measure, as well as the variants of the Euclidean measure and square of the Euclidean measure. Their properties were compared and synthetic measures were created on this basis. Infrastructural-technical variables referring to Polish counties were used as data in the creation of measures.
Efffect of Crop Plant Species on the Efficacy of Pheromone Traps for Monitoring of the Turnip Moth (Agrotis Segetum [Schiff.]) (Lep., Noctuidae)
Authors: Garnis Jakub , Dąbrowski Zbigniew 
Published: August 2008

Efffect of Crop Plant Species on the Efficacy of Pheromone Traps for Monitoring of the Turnip Moth (Agrotis Segetum [Schiff.]) (Lep., Noctuidae)
Common cutworm (Turnip moth) (Agrotis segetum), a serious polyphagous pest of many agricultural and horticultural crops, attacks a wide range of plant species in their various growth stages. The larvae are nocturnal in habits, spending the day hiding in the litter or in the soil and their presence is often only notice by farmers when the damage already occurred. Therefore development of an effective monitoring of the adults migration into a crop may help in controlling the pest. The pheromone traps are presently considered as the most effective monitoring system of A. segetum moth. Optimization of pheromone traps location will reduce cost of purchasing traps and labour and at the same time assuring collection of reliable information on A. segetum migration. The "on - farm research" with active participation of farmer in planning and execution of the project was carried out in the two growing seasons: 2005 and 2006 on 10 crop fields and natural vegetation of various ecological infrastructures of a selected representative farm in Piaski village, near Warsaw. A Delta type traps were used for monitoring. The relations between the dynamics of trapping month and density of traps per chosen area and characteristics of agrocenosis (type of crop and uncultivated land, drainage ditches, river embankment, etc.) were established. The collected data may be used in improving the present methods of short- and longterm forecasting of A. segetum population dynamics and optimize the pest chemical control.
Flavonoid Content and Antioxidant Activity of Caraway Roots (Carum Carvi L.)
Authors: Najda Agnieszka , Dyduch Jan , Brzozowski Norbert 
Published: August 2008

Flavonoid Content and Antioxidant Activity of Caraway Roots (Carum Carvi L.)
Zdolność znoszenia rodnika DPPH przez ekstrakty z korzeni kminku zwyczajnego wzrastała wprost proporcjonalnie do długości okresu wegetacji, zawartości flawonoidów i stężenia ekstraktów.
Exit of Safety Waterway Navigational Accident Probability Assessment Model Based on Navigation Cycles Concept
Authors: Gucma Lucjan 
Published: August 2008

Exit of Safety Waterway Navigational Accident Probability Assessment Model Based on Navigation Cycles Concept
The paper presents the concept of ships exit of waterway navigational accident probability assessment. Model enables to determine the total probability of accident during ships passage through waterways. Data from simulation trials or real experiments could be used as the input data.
Review of Road Safety Theories and Models
Authors: Jamroz Kazimierz 
Published: August 2008

Review of Road Safety Theories and ModelsIt has been 100 years since the first attempts at trying to explain why road accidents happen. There have been a number of theories and models studying this and road safety has become a field of scientific study. The paper will present how the theories and models of road safety developed and how they are used for road safety management. Four groups of the most advanced theories are distinguished: static theories, causal theories, system and behavioral theories. This division of the theories is followed in the models used for road safety analyses and studies.
Reliability, Availability and Cost Analysis of Large Multi-State Systems with Ageing Components
Authors: Kołowrocki Krzysztof , Soszyńska Joanna 
Published: August 2008

Reliability, Availability and Cost Analysis of Large Multi-State Systems with Ageing ComponentsBasic notions of the system multi-state reliability analysis are introduced. The multi-state series system with degrading components is defined and its exact reliability function is determined. The limit reliability function for large multi-state systems is introduced. An auxiliary theorem on limit reliability function of a large multi-state series system, which is necessary for its approximate reliability evaluation, is presented. On the basis of this auxiliary theorem some corollaries are formulated and proved and then applied to approximate reliability and availability determination of a large multi-state series system. Evaluations are given of a multi-state system reliability function, its mean lifetimes in the state subsets and their standard deviations, mean value and variance of the lifetime up to and the number of exceeding the system reliability critical state and its availability coefficient. The cost analysis of a multi-state series system is performed as well. The results are applied to a large telecommunication network reliability, availability and cost analysis.
Multi-Factor Index of Public Health: Empirical Analysis and Application in Economic Development of Transition Economies
Authors: Iryna Lukianenko , Larysa Krasnikova , Tamara Podvysotskaya 
Published: August 2008

Multi-Factor Index of Public Health: Empirical Analysis and Application in Economic Development of Transition EconomiesThe main focus of the paper is empirical investigation of health factor influence on economic growth in transition economies. Extending production function model of economic growth by constructed health indices the influence of health factor on the real output was examined. The main finding is that under majority of specifications health indices were found to be positive and significant. The influence of health on productivity growth in transition countries does not differ much from the health influence on productivity in the other countries groups.
Damage Hazard Model for Chosen Element of the Aircraft Structure Taking Into Account Fatigue Crack Development Stages
Authors: Tomaszek Henryk , Żurek Józef , Jasztal Michał 
Published: August 2008

Damage Hazard Model for Chosen Element of the Aircraft Structure Taking Into Account Fatigue Crack Development Stages
The subject of the present paper is the modeling of aircraft structure fatigue processes which endanger flight safety. It is assumed that the simple course of the process of aircraft structure elements fatigue encompasses the following stages: initiation of cracks, crack development to the limit value, destruction of the element of structure. These stages can be taken as random incidents or random processes. The paper provides a description of the two initial stages as random processes. The relations obtained allow to define the reliability of the structure element and to evaluate the damage hazard in given time period.
Customs Security in the European Union – Authorised Economic Operator (AEO)
Authors: Janowska-Bucka Edyta 
Published: August 2008

Customs Security in the European Union – Authorised Economic Operator (AEO)
The 1st January 2008 came into force the institution of an Authorised Economic Operator (abbreviation - AEO). By obtaining an AEO certificate, the Authorised Economic Operator becomes reliable in the European Community in the field of its customs operations and has right to take benefit because of this.
Unmanned Aerial Vehicle Used for Security Over the Baltic Sea
Authors: Nowakowski Mirosław , Rykaczewski Dariusz , Sabak Ryszard 
Published: August 2008

Unmanned Aerial Vehicle Used for Security Over the Baltic Sea
The paper presents new unmanned aerial vehicle (UAV) design for Regional and The Local Marine Fishery Inspectorates. Its specific design and maintenance specification allows to increase control abilities and will be the reason for increasing security of the sea sailing.
Risk in Water Supply System Crisis Management
Authors: Tchórzewska-Cieślak Barbara 
Published: August 2008

Risk in Water Supply System Crisis Management
Water supply system belongs to the so called critical infrastructure of cities, and it should be a priority task for waterworks and even for the local authorities to ensure the suitable level of its safety. This system is characterised by its continuous work and requires high reliability level for its operating as well as for its safety, it is unique and its particular elements have different functions and simultaneously they interact forming an integral whole. The main aim of this paper is to present problems associated with water supply system safety management in a crisis situation.
Risk Acceptation Principles in Transport
Authors: Szymanek Andrzej 
Published: August 2008

Risk Acceptation Principles in TransportIn this paper are presented few methodological problems related to valuing and acceptation risk in transport. In this lecture are presented such problems as: 1. philosophical, ethical and practical rules of risk acceptation. 2. ALARP, ALARA, GAMAB, MEM principles in relation to risk in transport.
Guselkumab for Pityriasis Rubra Pilaris and Dysregulation of IL-23/IL-17 and NFkB Signaling
Authors: Velasco Rose C. , Shao Connie , Cutler Brett , Strunck Jennifer , Kent Gail , Cassidy Pamela B. , Choate Keith , Greiling Teri M. 
Published: April 2024

ImportanceThere is no US Food and Drug Administration–approved treatment for pityriasis rubra pilaris (PRP), and it is common for patients to fail to experience improvement with several systemic options. Involvement of interleukin (IL) 23 suggests a potential therapeutic target.ObjectiveTo determine whether guselkumab, an IL-23p19 inhibitor, provides clinical improvement for participants with PRP and better understand gene and protein dysregulation in PRP.Design, Setting, and ParticipantsThis single-arm, investigator-initiated nonrandomized trial was conducted from October 2019 to August 2022 at a single-center academic university with participants from 8 states in the US. In total, 14 adults with moderate to severe PRP were enrolled; 12 completed the trial. Age-matched and sex-matched healthy controls provided skin and blood for proteomic and transcriptomic studies. The primary outcome was observed at 24 weeks, and additional follow-up occurred at 36 weeks.InterventionGuselkumab is a fully human immunoglobulin G1 λ monoclonal antibody that selectively binds and inhibits the p19 subunit of IL-23. Subcutaneous injections were given at the US Food and Drug Administration–approved dosing schedule for psoriasis over a 24-week period.Main Outcomes and MeasuresThe primary outcome was the mean change in the Psoriasis Area Severity Index (PASI) score at week 24. Secondary outcomes included pruritus, Dermatology Life Quality Index score, clinical response at week 36, and association with transcriptomics and proteomics expression.ResultsA per-protocol analysis was performed for the cohort of 4 female and 8 male patients who had a mean (SD) age of 56.5 (18.7) years. The mean improvement in PASI score, pruritus, and Dermatology Life Quality Index score was 61.8% (P &amp;lt; .001), 62.3% (P = .001), and 60.2% (P &amp;lt; .001), respectively. Nine participants (75%) achieved a 50% improvement in PASI. Among these clinical responders, at week 36, 8 of 9 achieved PASI75, and 6 of 9 achieved PASI90. No participants had pathogenic CARD14 gene variations. There was 1 serious adverse event that was not associated with the study drug. Proteomics and gene expression profiles identified dysregulation of a predominance of inflammatory pathways (such as T helper 17 and nuclear factor κ B) in participants with PRP who later responded well to treatment with guselkumab and stronger dysregulation of keratinocyte development pathways in individuals who did not respond to guselkumab.Conclusion and RelevanceThe results of this nonrandomized trial suggest that guselkumab has efficacy in treating refractory moderate to severe adult PRP.Trial RegistrationClinicalTrials.gov Identifier: NCT03975153