bluuebunny/crossref_metadata_2025_split huggingface dataset:
Dissolution dynamics of zirconia nanocluster resist
Authors: Ito Yuko Tsutsui , Kozawa Takahiro , Sakamoto Kazuo , Muramatsu Makoto 
Published: March 2024

Abstract
The metal oxide resists are promising materials for the high numerical aperture EUV lithography. In the metal oxide resists, the bridging ligands are generated upon exposure to radiations, which results in the formation of a pattern insoluble in developers. In this study, the dissolution dynamics of zirconia nanocluster resist was investigated using a quartz crystal microbalance method. The ligand was methacrylate. The developers used were ethyl, butyl, amyl, hexyl, 2-methylbutyl, and 3-methylbutyl acetates. The zirconia nanocluster resist showed characteristic dissolution dynamics. After the immersion into developers, the frequency slowly decreased with approximately constant impedance (no viscosity change of the film) for a while and then rapidly dissolved with the softening of resist film. The dependences of dissolution dynamics on the molecular structures of acetates and post exposure baking were clarified. The effect of branched structure at the third position of butyl was, in particular, remarkable.
Frecuencia y factores de riesgo para fungemia por especies de Candida
Authors: Benjumea Henao Santiago , Donado- Gómez Jorge Hernando , Agudelo-Restrepo Carlos , García-Rincón Cristian , Arboleda-Arias Natalia , Pérez-Giraldo Pablo Andrés , Ospina-Chaparro Lina , Ruiz-Giraldo Sebastián , Hidrón-Botero Alicia 
Published: March 2024

Objetivo: describir a la población de pacientes con candidemia, los factores de riesgo para desarrollar candidemia resistente a fluconazol, su frecuencia y distribución a lo largo de 10 años.
Material y métodos: estudio de cohorte retrospectiva multicéntrica. Se incluyeron pacientes diagnosticados con fungemia por Candida spp. entre enero de 2010 y diciembre de 2020; se realizó análisis multivariado por regresión logística para determinar los factores de riesgo asociados al desarrollo de fungemia por especies resistentes a fluconazol.
Resultados: hubo 286 pacientes con fungemia por Candida spp. El 19.9% de los aislamientos fueron resistentes a fluconazol y C. albicans fue la especie más comúnmente identificada (38.8%). En el grupo de resistencia a fluconazol predominaron C. glabrata (26%), C. krusei (25%) y C. tropicalis (21%). El uso previo de antifúngicos (OR 2.45; 95% CI 1.07–5.58; p = <0.033) y la desnutrición (OR 2.34; 95% CI 1.11 – 4.65; p = 0.015) se asociaron independientemente al desarrollo de candidemia por especies resistentes a fluconazol.
Conclusiones: la fungemia por especies de Candida no albicans y por especies resistentes a fluconazol tiene una frecuencia alta y viene aumentando en el tiempo. El uso previo de antifúngicos se asocia al desarrollo de candidemia fluconazol resistente al igual que la desnutrición, lo que es un hallazgo no reportado en estudios previos, el cual amerita confirmarse con investigaciones adicionales. El efecto de la infección por SARS-COV 2 en el desarrollo de candidemias es notorio, y su impacto real en nuestra población debe medirse en investigaciones posteriores.
Infección inesperada en tiempos de pandemia
Authors: Herrera Rueda Guillermo , Vargas-Díaz Maria Fernanda 
Published: March 2024

Hombre de 75 años con linfoma de Hodgkin. Residió en zona rural hasta hace dos décadas. Cinco días después de una dosis de esteroide de depósito consultó a urgencias por fiebre, tos y dolor abdominal. La radiografía del tórax mostró discretos signos de neumonía atípica inespecífica (Panel A) con PCR para SARS-CoV-2 negativa. Hubo empeoramiento requiriendo antibióticos y soporte ventilatorio. La imagen comparativa reveló opacidades alveolares bilaterales (Panel B) y la fibrobroncoscopia estructuras compatibles con larvas filariformes de Strongyloides (Panel C y D). Consecuentemente, se agregó al tratamiento ivermectina y albendazol.

Strongyloides puede mantener ciclos de reinfestación endógena incluso durante años. Los estados de inmunosupresión pueden facilitar la proliferación del parásito y así la ocurrencia del síndrome de hiper-infestación [1]. Tienen riesgo de esta condición pacientes residentes o visitantes de áreas endémicas que presenten coinfección por HTLV-1, uso de inmunomoduladores, terapia citotóxica o malignidad hematológica [3]. En nuestro medio es usual que concurran estos factores de riesgo así que es recomendable realizar desparasitación universal con ivermectina o albendazol a pacientes en dichas circunstancias [4,5].
Enseñanza y uso en Colombia del ultrasonido al pie de la cama del paciente
Authors: Núñez Ramos José Atilio , Velasco-Malagón Sergio 
Published: March 2024

Desde los invaluables aportes de Auenbrugger y Laennec, no asistíamos a una revolución de la exploración física como lo ha sido la introducción del ultrasonido realizado por el clínico y/o médico tratante del paciente. La ecografía realizada por especialistas clínicos en cualquier área (hospitalización, cuidados intensivos, servicio de urgencias, consulta externa, incluso en el domicilio) y de distintas formaciones (emergentólogo, internista, intensivista, anestesiólogo, neumólogo, nefrólogo, médico de familia, reumatólogo, cirujano general, etc), ha traído un nuevo aire a la exploración física. La evidencia del impacto del ultrasonido al pie del paciente es creciente y contundente en muchos aspectos. No solo permite que el clínico realice diagnósticos más certeros sino más rápidos cuando se compara con la dinámica usual, logrando así iniciar tratamiento más temprano y en algunos casos mejorando desenlaces clínicos como visitas a urgencias, re-hospitalizaciones, estancia hospitalaria, tiempos clínicos, entre otros.
En este artículo se comenta cómo surgió y cómo se enseña el Point-of-Care Ultrasound (POCUS por sus siglas en inglés) alrededor del mundo y lo que se viene haciendo en nuestro país desde distintos escenarios para lograr que el ultrasonido llevado a cabo por internistas y subespecialistas sea una realidad en la atención de los pacientes colombianos
Atypical Teratoid Rhabdoid Tumor of Central Nervous System in an Infant: A Case Report
Authors: Смирнова Анна Юрьевна , Суспицын Евгений Николаевич , Имянитов Евгений Наумович , Белогурова Маргарита Борисовна , Диникина Юлия Валерьевна 
Published: March 2024

Введение. Атипичные тератоид-рабдоидные опухоли (АТРО) являются чрезвычайно редкими агрессивными новообразованиями детского возраста с преимущественной встречаемостью у пациентов до 3 лет и доминирующей локализацией в пределах центральной нервной системы (ЦНС). Несмотря на интенсивные комплексные методы терапии, прогноз у данной категории больных остается неудовлетворительным.
Описание случая. Нами представлен случай агрессивного течения первично-метастатической АТРО в сочетании с глиомой низкой степени злокачественности у пациентки первого года жизни с синдромом предрасположенности к рабдоидным опухолям I типа (наследственной мутацией в гене SMARCB1). Применение комплексной интенсивной противоопухолевой терапии, согласно рекомендациям Медицинского университета Вены (MUV ATRT) и метрономной химиотерапии, сопровождалось длительным эффектом. Тем не менее при последующем стремительном прогрессировании заболевания все попытки лечения оказались безрезультатными, и пациентка скончалась спустя 44 месяца после постановки диагноза.
Diagnostic Options in Preoperative Assessment of Tumor Spread in Biliary Cancer — a Literature Review
Authors: Поляков Александр Николаевич , Романова Ксения Александровна , Котельников Алексей Геннадьевич , Умирзоков Анваржон Шовкатович , Сагайдак Игорь Всеволодович , Егенов Омар Алиевич , Тулин Павел Евгеньевич 
Published: March 2024

Цель обзора — определить роль методов предоперационного обследования у больных билиарным раком. При билиарном раке хирургическое вмешательство является потенциально радикальным методом, кандидаты на операцию — пациенты с локализованными формами опухоли. Стандартные лучевые методы диагностики, в первую очередь КТ и МРТ, позволяют оценить первичную опухоль, сосудистую инвазию, а также выявить регионарные и отдаленные метастазы. МРТ в большей степени подходит для оценки внутрипеченочной распространенности, точность в диагностике истинно-множественного поражения печени при внутрипеченочной холангиокарциноме достигает 100 %. Целесообразно применять МРТ для определения степени вовлечения желчных протоков. КТ более предпочтительна для диагностики внепеченочных метастазов, при сходной с МРТ чувствительностью метод обладает большей специфичностью (80,7 % против 72,9 %, р = 0,01) в определении лимфогенных метастазов. Также КТ позволяет более корректно оценить сосудистую инвазию и степень вовлечения прилежащих к опухоли структур — чувствительность достигает 90 %. Отметим, что даже совместное применение КТ и МРТ у больных билиарным раком не позволяет распознать до лапаротомии признаки нерезектабельности у 25-30 % больных. При подозрении на наличие метастазов целесообразно применять ПЭТ/КТ. Чувствительность метода в определении метастазов колеблется от 30 до 88 %, но стоит указать на высокую, выше 90 %, специфичность метода. Есть сторонники широкого применения диагностической лапароскопии при раке желчного пузыря, а также при раке проксимального отдела внепеченочных желчных протоков, объясняя свою точку зрения высоким, до 27 %, уровнем имплантационных метастазов. Далеко не все разделяют подобное мнение, отмечая невысокую, на уровне нескольких процентов, частоту выявления метастазов по брюшине при билиарном раке и возрастающие возможности лучевых методов диагностики.
Заключение. Планируя хирургическое вмешательство у больных билиарным раком, следует применять МРТ или КТ в качестве основного диагностического метода. Для решения узких диагностических задач перечень методов может быть расширен. ПЭТ/КТ и диагностическую лапароскопию следует использовать, если результаты стандартного обследования неоднозначны.
The First Photometric Analysis of Two Low-mass-ratio Contact Binary Systems in TESS Survey
Authors: Cheng Qiyuan , Xiong Jianping , Ding Xu , Ji Kaifan , Li Jiao , Liu Chao , Li Jiangdan , Luo Jingxiao , Lyu Xin , Han Zhanwen , Chen Xuefei 
Published: March 2024

Abstract
Low-mass-ratio (q) contact binary systems are progenitors of stellar mergers such as blue stragglers or fast-rotating FK Com stars. In this study, we present the first light curve analysis of two newly identified low mass-ratio contact binary systems, TIC 55007847 and TIC 63597006, that are identified from TESS. Both stars are classified as A-subtype contact binaries. We obtained the precise orbit periods for the two objects by using the O − C method, i.e., P = 0.6117108 day for TIC 55007847 and P = 0.7008995 day for TIC 63597006, and found an obvious periodic signal in the O − C curve of TIC 63597006. We suggest that the periodic signal comes from a third body. We further use the Markov chain Monte Carlo method with PHOEBE to derive the photometric solutions for the two binaries. The photometric solution for this object shows that the contribution of the third body is about 6%. Our analysis revealed that TIC 55007847 has an extremely low mass ratio of q = 0.08. By calculating the ratio of spin angular momentum to the orbital angular momentum J
s/J
o, we found that TIC 55007847 is very close to the instability threshold with J
s/J
o = 0.31, indicating that it may merge into a single, fast-rotating star in the future. For TIC 63597006, q = 0.14 and J
s/J
o = 0.15. This object is in a relatively stable evolutionary status at present.
The impact of long-distance travel to work on the health of commuting labour migrants: a literature review
Authors: Shitova Yuliya Y. 
Published: March 2024

This literature review analyzes the impact of commuting labour migration (CLM) on human health. Travel time is one of the major CLM factors affecting migrant health in both active and passive way. Fatigue and stress associated with commuting result in the increased blood pressure and risk of obesity.
The paper also dwells upon the impact of CLM on worker stress by gender. The article also explores the relationship between CLM and mortality. Work-life balance plays a crucial role in migrant health, while satisfaction with life can be compromised due to insecure life style associated with CLM. There is an effect of adaptation that can influence migrant health in a positive way.
In addition to negative aspects the article reviews benefits of CLM, including improved professional skills and higher income, and effective use of travel time. A special attention is payed to health of the Russian commuting migrants and their specific challenges and problems.
The article is a comprehensive review of scientific literature on CLM impact of human health. the results obtained can be used to develop programs and policies aimed at improving health of labour migrants and mitigating negative effects of commuting labour migration.
Mise en perspective de la politique du logement de la Région de Bruxelles-Capitale
Authors: Zimmer Pol 
Published: March 2024

Depuis sa naissance en 1989, la Région de Bruxelles-Capitale poursuit en matière de politique du logement deux objectifs essentiels et récurrents : garantir pour l’ensemble des ménages bruxellois l’exercice du droit à un logement adapté et accessible financièrement et, par ailleurs, maintenir sur le territoire régional une population permettant d’alimenter les ressources budgétaires de la Région eu égard au système de financement des Régions en Belgique.Après plus de trente d’existence, caractérisés notamment par une forte croissance démographique et par un appauvrissement de sa population, force est de constater que, à ce stade, la Région de Bruxelles-Capitale est en déficit de concrétisation de ses deux objectifs malgré un volontarisme proclamé et une activité législative importante et inventive.Cet article entend synthétiser les grandes évolutions de la politique du Logement portée par une Ville-Région dont certaines caractéristiques et leurs évolutions sont rappelées.Certaines raisons de la difficulté de concrétiser ces 2 objectifs sont abordées.Par ailleurs, une mise en perspective de cette politique est proposée à travers trois prismes différents qui plaident, de manière solidaire, pour accorder une importance accrue à cette politique pour laquelle d’autres chemins devraient être tentés en même temps qu’une meilleure utilisation des ressources budgétaires qui lui sont consacrées.La question peut être posée sur la manière d’accentuer l’opérationnalité des réponses publiques en revoyant le cadre général de cette politique héritière d’une histoire dont certains termes aujourd’hui ne correspondent pas à l’importance accrue qu’a pris l’accès au logement comme condition nécessaire d’une vie digne et satisfaisante et d’une citoyenneté libre et assumée.
La photographie d'Alan Kurdi en 2015. Une crise de conscience éditoriale en contexte migratoire
Authors: Blanc Anthony 
Published: March 2024

Le « choc » éprouvé en 2015 par les journalistes devant la photographie d'Alan Kurdi, un enfant syrien d'origine kurde retrouvé mort sur une plage turque, leur a inspiré la plus grande vigilance avant même sa publication. De manière à neutraliser les polémiques, les rédactions ont justifié leurs choix éditoriaux, anticipant ainsi la réaction de leurs lecteurs. Néanmoins, une controverse portant sur la publicisation de cette photographie a traversé les différentes instances médiatiques jusqu'aux publics. Cet article propose de revenir sur la couverture médiatique française de l'événement par les chaînes de télévision et les rédactions. Une étude de réception nous permet d'appréhender la réaction des internautes en réponse aux hésitations des médias. Si les journaux semblent avoir traversé une crise de conscience éditoriale face à cette photographie, nous nous interrogerons aussi sur ce qui a rendu cette image intolérable.
« Manipuler » et co-interpréter les images choc : vers une sémio-poïétique sociale ?
Authors: Appiotti Sébastien , Müller Susanne 
Published: March 2024

Dans cet article, nous cherchons à comprendre en quoi la manipulation plastique d'une image choc modifie le regard, et donc l'interprétation, tant du chercheur que de ses enquêtés. Dans un contexte de profond renouvellement de l'éducation critique à l'image, nous mobilisons une approche à la croisée des arts visuels et de la sémiotique sociale. Nous avons expérimenté cette dernière auprès d'étudiants de l'Institut régional du travail social de Lorraine sous la forme d'une co-analyse et d'une manipulation plastique d'une image d'un TGV médicalisé transportant des patients en soins intensifs atteints du Covid-19. Cette démarche s'inscrit dans Je cadre du projet de recherche collectif « Interpréter les images choc en temps de crise sanitaire ». Cet article sera l'occasion de rendre compte des principales hypothèses interprétatives ayant émergé de cette enquête ainsi que d'esquisser notre approche hybride, que nous proposons de dénommer « sémio-poïétique sociale ».
Artificial intelligence is being utilized to drive drug repurposing as a new strategy for managing asthmatic attacks
Authors: Daungsupawong Hinpetch , Wiwanitkit Viroj 
Published: March 2024

Abstract

OBJECTIVE:
This study assesses the efficacy of ChatGPT, an artificial intelligence language model, in assisting health-care professionals in selecting appropriate medications for the treatment of asthmatic attacks in males. A panel of experts specializing in rhinology and infectious diseases evaluates ChatGPT’s recommendations for ten fictional clinical scenarios involving asthmatic attacks. The objective of the study is to determine the extent to which ChatGPT can contribute to informed decision-making regarding the repurposing of drugs for managing this condition.

MATERIALS AND METHODS:
The expert panel assesses the accuracy and relevance of ChatGPT’s suggestions by comparing them to current medical research and literature. The findings demonstrate that ChatGPT consistently provides valuable recommendations for potential drug repurposing in the treatment of asthmatic attacks across all scenarios.

RESULTS:
These recommendations align with scientific evidence and published literature. While the range of treatment options may be limited, ChatGPT’s guidance proves beneficial for health-care professionals in identifying potential repurposed drugs. However, certain limitations, such as the need for more clinical data and the inability to customize treatment plans, should be addressed.

CONCLUSION:
Further research is required to enhance ChatGPT’s effectiveness in managing asthmatic attacks. Future studies should focus on refining the model’s capabilities, incorporating comprehensive clinical data, and enabling customization of treatment plans to make ChatGPT a valuable resource for health-care professionals dealing with asthmatic attacks in males.
Prevalence and Predicting Factors of Alcohol Use Among School Going Adolescents in a Hilly State of Northern India
Authors: Kumari Durgesh , Gupta Anmol , Thakur Anita 
Published: March 2024

Abstract

Background:
Alcohol use among adolescents is rising globally. This habit starts in adolescence and continues throughout their life. Alcohol addiction is associated with many other risky behaviors. Social environmental interventions will be an effective measure to control the problem of alcohol use.

Objectives:
The purpose of this study was to estimate the prevalence of alcohol use among adolescents and to investigate the associated risk and protective factors.

Methods:
A cross-sectional study was carried out among school going adolescents in the hilly state Himachal. A pre-validated, self-administered questionnaire was used for data collection.

Results:
The prevalence of alcohol use in adolescent was 6.1% (10.7% in males and 0.4% in females). Binary logistic regression model revealed that parent’s and peer’s drinking behavior significantly predicts an adolescent’s drinking behavior.

Conclusion:
Our research supports the need for an adolescent health program involving school, peers, and family. Life skill education should be given to the adolescents to inculcate the resilience so that they learn to say no to peers who try to pull them into such habits.
Impact of Universal Health Insurance on Total Ischemia Time and Door-to-Balloon Time in STEMI
Authors: Upadhyay Amar Nath , Dhasmana Manira , Kumar Barun 
Published: March 2024

Abstract

Introduction:
We studied the impact of a Universal Health Insurance (UHI) Scheme introduced in India on total ischemia time (an important determinant of ST-elevation myocardial infarction [STEMI] outcome).

Materials and Methods:
This is a retrospective hospital-based comparative study which evaluated the total ischemia time (min) of all the patients presenting with STEMI and undergoing primary angioplasty before (Group A) and after (Group B) implementation of this scheme.

Results:
A total of 221 patients (mean age: 54.18 ± 13.02 years in Group A and 57.59 ± 11.42 years in Group B) were included in the study. Median pain to first medical contact time was 300 and 360 min (P = 0.49), whereas the median first medical contact to percutaneous coronary intervention PCI center time was 330 and 210 min (P = 0.32), for Groups A and B, respectively. A statistically significant difference was noted in the mean door-to-device time between two groups (67.46 ± 33.10 min in Group A vs. 58.48 ± 12.99 min in Group B; P = 0.02).

Conclusions:
A significant difference in door-to-balloon time was found after implementation of UHI, but total ischemia time was no different. It emphasizes the importance of establishing a system of STEMI care that can decentralize the benefits of early reperfusion like hub-and-spoke model.
Anthropometric Indices and Type 2 Diabetes Mellitus as a Risk Factor in Predicting Nonalcoholic Fatty Liver Disease – A Prospective Study in Indian Population
Authors: Suvarna Renuka , Nasir Mohammed A. , Stanley Weena , Prabhu M. Mukhyaprana 
Published: March 2024

Abstract

Background:
The different anthropometric indices have different predictive values of nonalcoholic fatty liver disease (NAFLD) in various populations. Since obesity is a common cause of NAFLD and diabetes, therefore, it is critical to correlate the various anthropometric indices as a risk factor in terms of NAFLD and diabetes in the Indian population. In view of reported association between obesity and NAFLD, the study was employed to analyze the relationship of various anthropometric indices (body mass index [BMI], a body shape index [ABSI], waist-height ratio [WHtR], etc.) with NAFLD and to comment, if possible, which among them has the highest predictive value in patients with type 2 diabetes.

Material and Methods:
Data of 220 diabetic patients (36–80 years) were analyzed. Anthropometric data were collected using standard methods. Routine biochemical investigations data were used. Ultrasonography was used to assess liver status for NAFLD.

Results:
Based on the results, Waist height ratio [WHtR] and BMI had better correlation with NAFLD than ABSI. The desirable WHtR cutoff value was 0.545 with 62% of sensitivity and 62% of specificity. The cut off for BMI and ABSI were 24.6 and 0.805, respectively, with 65% of sensitivity and 62% of specificity for BMI and 63% of sensitivity and 42% of specificity for ABSI.

Conclusion:
There is a strong association of BMI and ABSI with NAFLD in this study. Public health measures to limit overnutrition and management of obesity are essential to prevent NAFLD, and as its negative health effects on type 2 diabetes mellitus.