bluuebunny/crossref_metadata_2025_split huggingface dataset:
Adherence to antiretroviral therapy and determining factors in adults living with HIV receiving services at public health facilities amidst the COVID-19 crisis in Bahir Dar city, Northwest Ethiopia
Authors: Gela Chalachew Dessie , Tsegaye Gebiyaw Wudie , Shibesh Belayneh Fentahun 
Published: April 2024

BackgroundThe COVID-19 pandemic has presented new challenges to adhering to ART, and its influence on adherence and related factors has not been thoroughly studied. This study examines ART adherence and its associated factors during the COVID-19 pandemic.MethodsA cross-sectional study was conducted on HIV-positive individuals receiving care and treatment in public health facilities. A total of 612 participants were selected using a multi-stage sampling procedure. Data were collected through interviewer-administered questionnaires and chart reviews. We used Epi-data for data entry and Stata for data analysis.ResultsGood adherence to antiretroviral therapy in this study was 76.5% (95% CI, 72.9, 79.7). Divorced marital status (AOR = 0.45,95%CI:0.22,0.90), regular follow-up (AOR = 3.01,95%CI:1.81,5.01), adherence counseling and information in the context of COVID-19 pandemic (AOR = 2.57,95%CI:1.63,4.08), and knowledge about ART (AOR = 1.81,95%CI:1.11,2.94) were significantly associated with adherence to antiretroviral therapy.ConclusionThe observed adherence rate in this study was lower than the World Health Organization recommendation and previous studies. The study highlighted the importance of addressing adherence to ART among HIV-positive adults during the COVID-19 pandemic and other upcoming emerging and reemerging outbreaks. Strategies to improve adherence should consider factors such as marital status, regular follow-up, provision of counseling and information, and enhancing knowledge about ART.
Experiences of male irregular migrants during their migration process and reception in Spain: lessons learned from the COVID-19 pandemic
Authors: García-López Dulcenombre de María , Jiménez-Lasserrotte María del Mar , Briones-Vozmediano Érica , Ruiz-Fernández María Dolores , Hernández-Padilla José Manuel , Granero-Molina José 
Published: April 2024

BackgroundThe causes behind migration movements are complex. The COVID-19 pandemic highlighted how several countries failed to respond to the virus adequately, while simultaneously infringing on people’s rights. Male irregular migrants fled their countries of origin and embarked on a perilous migration journey to Spain. The highly restrictive COVID-19 measures and border closures affected the mobility of male irregular migrants, whose reception in the host country posed a challenge. It led to the establishment of emergency facilities to accommodate male irregular migrants affected by COVID-19, which had repercussions on their mental health. The aim of this study was to describe and understand the experiences of male irregular migrants throughout their migration process and reception in Spain during the COVID-19 pandemic.MethodsQualitative descriptive study. Sixteen male irregular migrants participated in this study. Data were collected between January and March 2023 through 16 one-on-one in-depth interviews. Thematic analysis was used to analyze the qualitative data using ATLAS.ti computer software.ResultsThree main themes emerged: (1) How the COVID-19 pandemic drove male irregular migrants to leave their countries of origin, (2) How COVID-19 lockdown policies affected the migration journey, and (3) Receiving male irregular migrants in a pandemic: a housing labyrinth marked by isolation and loneliness.ConclusionThe COVID-19 pandemic increased the social, employment and health inequalities experienced by male irregular migrants. Border closures exacerbated the migration journey and the social stigmatization of this group, who were seen as carriers of the virus in both transit and host countries. Strict control measures in emergency and reception facilities had a significant psychological impact on the male irregular migrants due to the social isolation they experienced. Health institutions should develop programs to guarantee the care needs of irregular migrants.
Characterization of the Worthen Sparrow (Spizella wortheni)’s Nest Building Materials in Northeastern Mexico
Authors: Suarez Eliseo B. , Mellado Miguel , Luna Marcos , Lozano Eloy A. , Calderon Guadalupe , Angel Yesenia , Angel Oscar , Medina Mayra L. , García José E. 
Published: April 2024

The study was conducted within a well-managed beef cattle operation in northeastern Mexico. Each nest was weighed and dissected to obtain the plant and animal material used to build the nests. The number of materials present per nest and relative frequency were determined. Twenty-one building materials were used. Over the years, Muhlenbergia torreyi represented 85.5% of the total biomass of the nests, and Aristida longiseta, Bouteloua gracilis, Brickellia canescens, Purshia mexicana and Cirsium ehrenbergii constituted 2.45, 2.80, 2.44, 1.34 and 1.11% of the total biomass, respectively. The above-mentioned grasses represented 95.62% of the total biomass. Material of animal origin was horse and cow hair, which represented 0.84 and 0.58% of the total biomass, respectively. It was concluded that, at the study site, Muhlenbergia torreyi was a key nest-building material for the Worthen sparrow nest.
Application of RFSoC-based arbitrary waveform generator for coherent control of atomic qubits
Authors: Maetani Kazunori , Machino Akinori , Koike Keisuke , Morisaka Shinichi , Miyanishi Koichiro , Kobayashi Toshiki , Toyoda Kenji , Negoro Makoto , Miyoshi Takefumi , Ohira Ryutaro 
Published: April 2024

Abstract
This study evaluates an AMD Zynq Ultrascale+ RF System-on-Chip (RFSoC) as an arbitrary waveform generator (AWG) for controlling atomic qubits coherently. We explore the advantages of using an RFSoC-based AWG for atomic qubit manipulation and experimentally demonstrate its utility in quantum computing. Our findings demonstrate that RFSoC is a scalable solution for developing large-scale quantum computers with atomic qubits, offering a promising approach for applications.
Improvement of photothermal heating efficiency of Si plasmonic waveguide heaters with ring resonators
Authors: Shimizu Hiromasa , Shinohara Kota , Hasumi Masahiko 
Published: April 2024

Abstract
We report improved photothermal heating efficiency of Si plasmonic waveguide heaters integrated with ring resonators by enhancing the interaction of the propagating light and metal with a thinner buffer layer. The resonance wavelength was shifted towards a longer wavelength by inputting transverse magnetic mode light, and the amount of shift was influenced by the length of the region deposited with the Co thin film and the gap of the directional coupler. The local temperature rise of 580 K was achieved by injecting 6.3 mW of light, and photothermal conversion efficiency as high as 106 K mW−1 was obtained in a Si plasmonic waveguide deposited with 0.5 μm long Co thin films, showing improvement compared with previous devices. Discussion on the heating efficiency based on the propagation loss and cavity loss in the ring resonators is given based on experimental results, to realize compact photothermal waveguide heaters for various applications.
Incidência de novos casos de hanseníase na região Sudeste (2018-2023): Um estudo ecológico
Authors: Salaroli Robson , Ambrósio Marcos Flávio Spínola , Lordão Daniel Batista Monte Alto do Vale , Aguiar Lorena Louise Botelho de , Aguiar Thais Caroline Botelho de , Silva Fernanda Campolina Alves , Filho Glauber Pablo Soriano de Carvalho , Agostini Beatriz Montezano Oliveira , Soares Leonardo Ricardo , Martins Lívia Deziré , Martins Letícia Deziré , Rezende Larissa Pereira 
Published: April 2024

A hanseníase é uma doença infecciosa crônica causada pela bactéria Mycobacterium leprae. Ela afeta principalmente a pele, os nervos periféricos, as mucosas das vias aéreas superiores e os olhos. A hanseníase é uma das doenças mais antigas da humanidade e, apesar dos avanços no seu tratamento, ainda representa um desafio de saúde pública em várias partes do mundo, especialmente em regiões tropicais e subtropicais. Este estudo ecológico busca analisar a incidência de novos casos da doença nos estados de São Paulo, Rio de Janeiro, Minas Gerais e Espírito Santo, durante entre os anos de 2018 a 2023. Para tal, utilizaram-se dados do Sistema de Informação de Agravos de Notificação (SINAN) do Departamento de Informática do Sistema Único de Saúde (DATASUS) para tabulação e analise do comportamento da doença na região. A análise abrangerá não apenas o número absoluto de casos, mas também taxa de incidência e prevalência por 100.000 habitantes, permitindo uma comparação mais precisa entre os estados analisados. Além disso, serão exploradas características sociodemográficas dos pacientes, como idade e raça/etnia, a fim de identificar grupos de maior vulnerabilidade à doença. Desse modo, este trabalho visa compreender a distribuição geográfica e temporal da hanseníase na região Sudeste no período avaliado, bem como identificar possíveis fatores associados ao aumento ou diminuição dos casos.
Impact of COVID-19 on Preventable Blindness Detection in Bali, Indonesia
Authors: Lestari Ni Putu Dharmi , Gede Benny Setia Wirawan  , I Putu Rustama Putra  , Ni Wayan Sedani  , Cynthia Dewi M  
Published: April 2024

Introduction: WHO, and the Indonesian government, have agreed to a plan to eradicate preventable blindness by 2020 in VISION 2020. However, the COVID-19 pandemic has caused a strain on the healthcare system. It is difficult to assess the impact of the pandemic on preventable blindness. Here we approach the issue by evaluating hospital visits for visual impairments in one regency in Bali, Indonesia.
Methods: We collected outpatient visit records from three hospitals providing ophthalmologic clinics in Tabanan, Bali, Indonesia, a regency of 445 thousand people. We then conducted a descriptive analysis of the general changes in outpatient visits to these clinics and changes observed in different diagnoses identified as causes for preventable blindness.
Results: The result showed a 35% downtrend in outpatient visits to the ophthalmologic clinic throughout the provinces. A more pronounced downtrend (45.22%) was observed for one public hospital that also serves as a COVID-19 referral hospital compared to private hospitals (around 30% each). By diagnoses, visits for cataracts were shown with a less severe downtrend compared to glaucoma, pterygium, and refractive disorders.
Conclusion: Our study found a downtrend in outpatient visits for visual impairment in ophthalmologic clinics, which may be attributed to COVID-19 preventive measures by the hospital as well as patient reluctance due to fear of COVID-19 transmission. Public health communication needs to address this fear to recover patient confidence while maintaining vigilance in practicing COVID-19 preventive behavior.
Taurine attenuates activation of hepatic stellate cells by inhibiting autophagy and inducing ferroptosis
Authors: Li Sen , Ren Qian-Jun , Xie Can-Hao , Cui Yang , Xu Li-Tao , Wang Yi-Dan , Li Su , Liang Xing-Qiu , Wen Bin , Liang Ming-Kun , Zhao Xiao-Fang 
Published: April 2024

BACKGROUND
Liver fibrosis is a compensatory response during the tissue repair process in chronic liver injury, and finally leads to liver cirrhosis or even hepatocellular carcinoma. The pathogenesis of hepatic fibrosis is associated with the progressive accumulation of activated hepatic stellate cells (HSCs), which can transdifferentiate into myofibroblasts to produce an excess of the extracellular matrix (ECM). Myofibroblasts are the main source of the excessive ECM responsible for hepatic fibrosis. Therefore, activated hepatic stellate cells (aHSCs), the principal ECM producing cells in the injured liver, are a promising therapeutic target for the treatment of hepatic fibrosis.
AIM
To explore the effect of taurine on aHSC proliferation and the mechanisms involved.
METHODS
Human HSCs (LX-2) were randomly divided into five groups: Normal control group, platelet-derived growth factor-BB (PDGF-BB) (20 ng/mL) treated group, and low, medium, and high dosage of taurine (10 mmol/L, 50 mmol/L, and 100 mmol/L, respectively) with PDGF-BB (20 ng/mL) treated group. Cell Counting Kit-8 method was performed to evaluate the effect of taurine on the viability of aHSCs. Enzyme-linked immunosorbent assay was used to estimate the effect of taurine on the levels of reactive oxygen species (ROS), malondialdehyde, glutathione, and iron concentration. Transmission electron microscopy was applied to observe the effect of taurine on the autophagosomes and ferroptosis features in aHSCs. Quantitative real-time polymerase chain reaction and Western blot analysis were performed to detect the effect of taurine on the expression of α-SMA, Collagen I, Fibronectin 1, LC3B, ATG5, Beclin 1, PTGS2, SLC7A11, and p62.
RESULTS
Taurine promoted the death of aHSCs and reduced the deposition of the ECM. Treatment with taurine could alleviate autophagy in HSCs to inhibit their activation, by decreasing autophagosome formation, downregulating LC3B and Beclin 1 protein expression, and upregulating p62 protein expression. Meanwhile, treatment with taurine triggered ferroptosis and ferritinophagy to eliminate aHSCs characterized by iron overload, lipid ROS accumulation, glutathione depletion, and lipid peroxidation. Furthermore, bioinformatics analysis demonstrated that taurine had a direct targeting effect on nuclear receptor coactivator 4, exhibiting the best average binding affinity of -20.99 kcal/mol.
CONCLUSION
Taurine exerts therapeutic effects on liver fibrosis via mechanisms that involve inhibition of autophagy and trigger of ferroptosis and ferritinophagy in HSCs to eliminate aHSCs.
Analysis of the Financial and Technical Feasibility of Erection a Herbal Medicine Factory Pt. Tugu Semar Production Using the Systematic Layout Planning Method
Authors: Nada Muhammad Bisyri , Oetomo Dedy Setyo , Hermawan Asep 
Published: April 2024

Abstract: With the increasing demand for herbal medicine and efforts to reduce the import value of herbal drugs, PT Tugu Semar Production plans to enhance production by establishing a new factory. The planning utilizes the Systematic Layout Planning (SLP) method and conducts a financial feasibility analysis related to the investment. The prospective location is in Blitar, with a production capacity of 100 liters or 500 bottles. The research also encompasses a financial feasibility analysis using capex data of Rp. 4,539,800,000 and first-year opex of Rp. 3,646,980,053. The financial feasibility analysis results in an Internal Rate of Return (IRR) of 21%, indicating the financial viability of the investment. With a significant IRR, the project estimates a return on investment within 4 years and 8 months. These findings provide a comprehensive insight into the success of herbal medicine factory planning using the SLP method and instill confidence that this investment holds high financial feasibility potential. The implications of this research are expected to offer strategic guidance to PT Tugu Semar Production in decision-making concerning the development of the herbal medicine factory in Blitar.
Keywords: Systematic Layout Planning; NPV ; IRR ; PBP
The Potential of Cynodon Dactylon and Lolium Perenne 'Brightstar' as Phytoremediator Agents in Dealing with the Problem of Sea Water Intrusion in the North Coastal Area of Karawang
Authors: Rizkiah Riza , Sewiko Roni , Pranoto Aris Kabul , Pasaribu Roberto Patar , Djari Anthon Anthonny , Rahman Abdul , Ismail R Moh , Handayani Endy , Luciana Luciana , Mulyana Muhammad Agus 
Published: April 2024

Sea water intrusion is a process where sea water is mixed with underground water around the coast, causing the ground water to become salty because it is contaminated by sea water which is rich in salt. Sea air that enters the ground causes the air to become unfit for consumption and causes the land to become unproductive for planting. People in the Pakis Jaya area, Karawang face difficulties, especially regarding land use for agricultural activities. This is because the land used for cultivating plants is saline soil with a high salt content. Phytoremediation is a method used to clean air or soil contaminated with pollutants, by using the ability of plants to absorb these substances. Cynodon Dactylon and lolium Perenne Brightstar plants are a type of grass that can be used to reduce high salt levels in the soil because these plants are able to live in places with high salinity and also have the ability to reduce salinity by absorbing chloride ions in it. The methods used in this research consisted of: Sampling Process, Plant Acclimatization Stage, Salinity Concentration Test before and after planting grass in Soil Media. The test results showed that the salt content in the soil before planting was 19.20 dS/m and after planting it was 0.02-0.03 dS/M.
Numerical values modulate size perception
Authors: Avitan Aviv , Marom Dror , Henik Avishai 
Published: April 2024

AbstractThe link between various codes of magnitude and their interactions has been studied extensively for many years. In the current study, we examined how the physical and numerical magnitudes of digits are mapped into a combined mental representation. In two psychophysical experiments, participants reported the physically larger digit among two digits. In the identical condition, participants compared digits of an identical value (e.g., “2” and “2”); in the different condition, participants compared digits of distinct numerical values (i.e., “2” and “5”). As anticipated, participants overestimated the physical size of a numerically larger digit and underestimated the physical size of a numerically smaller digit. Our results extend the shared-representation account of physical and numerical magnitudes.
Estimer la mortalité aux âges élevés dans les pays à données incomplètes : les estimations basées sur la survie des parents sont-elles affectées par des biais de sélection ?
Authors: Menashe-Oren Ashira , Masquelier Bruno , Schlüter Benjamin-Samuel , Helleringer Stéphane 
Published: April 2024

La mortalité aux âges élevés reste peu documentée dans les pays où les systèmes d’enregistrement et les statistiques de l’état civil sont incomplets. Les enquêtes comportant des questions sur la survie des parents peuvent contribuer à combler cette lacune en fournissant des estimations de la mortalité des plus de 50 ans. Notre article évalue si des biais de sélection pourrait altérer la qualité de ces estimations. Nous analysons les données de trois observatoires de population et de santé regroupant 9 600 femmes et 8 500 hommes. Nous appliquons des modèles de Cox afin d’estimer la mortalité des femmes et des hommes âgés de 50 à 89 ans en fonction du nombre de leurs filles adultes (qui sont généralement les répondantes aux enquêtes). Les résultats indiquent que les personnes sans enfant vivant au moment de l’enquête font face à un risque de décès plus important. Les estimations de mortalité déduites des déclarations sur la survie des parents sont donc susceptibles de sous-estimer les niveaux de mortalité après 50 ans, même si aucun biais systématique n’apparaît clairement. La collecte de données sur la survie des parents constitue finalement un outil prometteur pour mesurer la mortalité aux âges élevés, étant donné le faible risque de biais de sélection.
Le non-verbal à l’ère numérique
Authors: Barlow Julie 
Published: April 2024

À mesure qu’augmente le nombre d’outils de communication, les questions sur la façon de les utiliser et de les interpréter se multiplient. Combien de temps peut-on attendre pour répondre à un courriel ? Puis-je téléphoner directement à mon patron ou devrais-je lui envoyer un texto avant ? L’émoji « visage triste » à la fin d’un texte signifie-t-il que je suis fâché ? Déçu ? Désolé ?
Les collections de vêtements d’enfant, problèmes et perspectives
Authors: Guennec Aude Le , Rose Clare 
Published: April 2024

La mode enfantine reste un sujet muséologique marginal dans le paysage muséographique contemporain et principalement dans les institutions qui devaient en avoir la charge : les musées de mode et musées de société. Reflétant l’intérêt tardif pour l’histoire de l’enfance, la mode enfantine a rarement fait l’objet d’une collecte patrimoniale et d’une documentation cohérente dans ces institutions. Par ailleurs, reposant généralement sur des dons familiaux aléatoires, les collections ne montrent pas la réalité et les usages des vêtements du quotidien dans toutes les couches de la société. Du fait de la disparition de cette mémoire matérielle enfantine, les musées négligent les pratiques vestimentaires des enfants et les excluent des processus de patrimonialisation de leur culture quand bien même ceci est l’un de leurs droits fondamentaux (Convention relative aux droits de l’enfant, 1989). À travers trois études de cas de musées français et britanniques particulièrement associés à la conservation et à la valorisation de l’histoire de la mode enfantine, cet article analyse l’état actuel du patrimoine vestimentaire enfantin et son effet sur notre compréhension des mécanismes de socialisation des enfants. Il explore les avantages d’une approche patrimoniale cohérente pour préserver la mémoire de la mode enfantine, comprendre les interactions des enfants avec leur propre culture, et envisager les perspectives que cette approche pourrait apporter aux jeunes en termes d’éducation et de citoyenneté.