bluuebunny/crossref_metadata_2025_split huggingface dataset:
Combined transcatheter aortic valve and tricuspid valve‐in‐valve implantation in a patient with a mitral mechanical prosthesis
Authors: Lima Maria Rita , Brito João , Almeida Manuel , Teles Rui Campante 
Published: April 2024

AbstractDespite progressively uncommon in Western countries, rheumatic heart disease still portrays a significant global burden. In elderly or high‐surgical risk patients, plurivalvular disease may require a complex percutaneous approach. Transcatheter aortic valve implantation (TAVI) in patients with previous monoleaflet mitral prosthesis is challenging due to interference between the aortic valve and the rigid mitral mechanical prosthesis “ring.” Prior cases report the use of CoreValve or Edwards Sapien aortic valves in patients with adequate mitro‐aortic distance. Performing a second major procedure, such as tricuspid valve‐in‐valve (TVIV), sequentially during a single percutaneous intervention, increases treatment complexity. An 83‐year‐old woman with rheumatic heart disease, with previous implantation of a Bjork–Shiley monoleaflet mitral prosthesis, and Carpentier‐Edwards 29 tricuspid bioprosthesis presented with decompensated heart failure due to severe aortic stenosis and tricuspid bioprosthesis stenosis. After HeartTeam discussion, the patient was deemed as inoperable due to a prohibitive surgical risk. As an alternative, a TAVI (Navitor FlexNav) and a transcatheter TVIV replacement (Edwards Sapiens 3 Ultra) were discussed and proposed, with both techniques being performed sequentially in a single procedure. TAVI in a patient with a previous monoleaflet mitral mechanical prosthesis and TVIV may be a feasible approach in inoperable patients with plurivalvular disease.
Calcium‐Based Metal‐Organic Framework: Detection and Idiosyncratic Removal of Copper by Nano‐Particle Deposition
Authors: Mondal Pallav , Brahma Bhaskar K. , Vali Dudekula Khasim , Ray Joydeep , Kasu Jyothirlatha V. N. , Gangopadhyay Avishek , Laha Sourav , Adhikari Utpal 
Published: April 2024

AbstractA novel calcium‐based metal‐organic framework (CaMOF@LSB) was designed and synthesized, exhibiting dual functionality for both selective detection and removal of Cu2+ ions from aqueous solutions. The framework‘s stability, including solvent and pH variations, was established with notable thermal resilience. Colorimetric Cu2+ detection (≥5 ppm) with a high capture capacity of 484.2 mg g−1 by CaMOF@LSB places this material among the few that ensure efficient colorimetric detection and high removal capabilities of Cu2+ ions. Batch adsorption experiments revealed pH‐dependent behavior and competitive interactions. Langmuir and pseudo‐second‐order kinetics models aptly described adsorption isotherms and kinetics, respectively. Thermodynamic assessments confirmed spontaneous and endothermic adsorption. Mechanistically, nanoparticle deposition contributes to the Cu2+ uptake. CaMOF@LSB also exhibited one of the best removal behaviour of Cu2+ by means of oxide formation on the surface. Regeneration of CaMOF@LSB was achieved by simple sonication in 0.1 M aqueous NaOH solution. The recyclability was also tested up to 5 cycles, and it exhibited a small decrease in adsorption capacity observed across the cycles. This research presents a promising avenue for addressing heavy metal pollution using metal‐organic frameworks, thereby offering potential applications in water purification and environmental pollution monitoring and remediation.
Exploration of Vitamin B6‐Based Redox‐Active Pyridinium Salts Towards the Application in Aqueous Organic Flow Batteries
Authors: Nechaev Anton A. , Gonzalez Gabriel , Verma Prachi , Peshkov Vsevolod A. , Bannykh Anton , Hashemi Arsalan , Hannonen Jenna , Hamza Andrea , Pápai Imre , Laasonen Kari , Peljo Pekka , Pihko Petri M. 
Published: April 2024

AbstractPyridoxal hydrochloride, a vitamin B6 vitamer, was synthetically converted to a series of diverse redox‐active benzoyl pyridinium salts. Cyclic voltammetry studies demonstrated redox reversibility under basic conditions, and two of the most promising salts were subjected to laboratory‐scale flow battery tests involving galvanostatic cycling at 10 mM in 0.1 M NaOH. In these tests, the battery was charged completely, corresponding to the transfer of two electrons to the electrolyte, but no discharge was observed. Both CV analysis and electrochemical simulations confirmed that the redox wave observed in the experimental voltammograms corresponds to a two‐electron process. To explain the irreversibility in the battery tests, we conducted bulk electrolysis with the benzoyl pyridinium salts, affording the corresponding benzylic secondary alcohols. Computational studies suggest that the reduction proceeds in three consecutive steps: first electron transfer (ET), then proton‐coupled electron transfer (PCET) and finally proton transfer (PT) to give the secondary alcohol. 1H NMR deuterium exchange studies indicated that the last PT step is not reversible in 0.1 M NaOH, rendering the entire redox process irreversible. The apparent reversibility observed in CV at the basic media likely arises from the slow rate of the PT step at the timescale of the measurement.
Benzoselenadiazole‐Functionalized H‐Bonded Arylamide Foldamers: Solvent‐Responsive Properties and Helix Self‐Assembly Directed by Chalcogen Bonding in Solid State
Authors: Liu Chuan‐Zhi , Zhang Chi , Li Chang‐Gen , Chen Hui‐Bin , Yang Wen , Li Zhong‐Yi , Hu Zhi‐Yuan , Xu Liang , Zhai Bin , Li Zhan‐Ting 
Published: April 2024

AbstractIn this study, a series of H‐bonded arylamide foldamers bearing benzoselenadiazole ends with solvent‐responsive properties have been synthesized. In dichloromethane or dimethyl sulfoxide solvents, the molecules exhibit meniscus or linear structures, respectively, which can be attributed to the unique intramolecular hydrogen bonding behavior evidenced by 1D 1H NMR and 2D NOESY spectra. UV‐vis spectroscopy experiments show that the absorption wavelength of H‐bonded arylamide foldamers are significantly red‐shifted due to the presence of benzoselenadiazole group. In addition, the crystal structures reveal that effective intermolecular dual Se ⋅ ⋅ ⋅ N interactions between benzoselenadiazole groups induce further assembly of the monomers. Remarkably, supramolecular linear and double helices structures are constructed under the synergistic induction of intramolecular hydrogen bonding and intermolecular chalcogen bonding. Additionally, 2D DOSY diffusion spectra and theoretical modelling based on density functional theory (DFT) are performed to explore the persistence of intermolecular Se ⋅ ⋅ ⋅ N interactions beyond the crystalline state.
The threshold energy of low temperature Langevin dynamics for pure spherical spin glasses
Authors: Sellke Mark 
Published: April 2024

AbstractWe study the Langevin dynamics for spherical ‐spin models, focusing on the short time regime described by the Cugliandolo–Kurchan equations. Confirming a prediction of Cugliandolo and Kurchan, we show the asymptotic energy achieved is exactly in the low temperature limit. The upper bound uses hardness results for Lipschitz optimization algorithms and applies for all temperatures. For the lower bound, we prove the dynamics reaches and stays above the lowest energy of any approximate local maximum. In fact the latter behavior holds for any Hamiltonian obeying natural smoothness estimates, even with disorder‐dependent initialization and on exponential time‐scales.
Detection of algal tiny objects based on morphological features
Authors: Yuan Shuai , Peng Ningkang , Shi Ziyan , Zhao Sichuan , Li Runcheng , Gu Yanhui , He Huan 
Published: April 2024

SummaryThe dense and toxic blooms formed by cyanobacteria in aquatic environments pose significant threats to public health and aquatic ecosystems. Timely monitoring and prevention of cyanobacterial blooms in freshwater bodies are thus imperative. Although object detection methods have been applied in the field of algae identification, existing research faces several challenges. A primary issue is the overly idealistic setting of training sets, which are disconnected from the actual water quality environments, impeding practical algae identification and water quality monitoring. In this paper, we collect 2024 microscopic images of algae from a reservoir in Southern China, forming a comprehensive and diverse dataset for object detection. Addressing the aforementioned challenges, we propose an attention‐based strategy for the detection of tiny algal objects, which effectively samples and extracts features from algal targets. Our model uniquely leverages the morphable characteristics of algae, enhancing the accuracy and efficiency of identification. The training and improvement results of this model presented in our study are expected to aid in establishing a future system for real‐time algae monitoring and water quality assessment.
Cross‐Polarization Solid‐State NMR Quantification of Species within Pores of Metal‐Organic Frameworks: A Case Study of α‐Mg3(HCOO)6
Authors: Wu Changzong , Xu Jun 
Published: April 2024

AbstractThe quantitative measurement of adsorbed guest species within metal‐organic framework (MOF) pores is of fundamental importance for evaluating the adsorption performance of MOFs. However, routine analytic techniques such as thermogravimetric analysis cannot distinguish the contribution from species adsorbed within pores, species adsorbed on the surface, and gas phase or liquid phase encapsulated in the inter‐crystalline space. Herein, we developed a new quantification method based on the cross‐polarization (CP) solid‐state nuclear magnetic resonance (ssNMR) technique, in which only the species within MOF pores are selectively probed due to the dramatically reduced mobility. Using the commercialized MOF α‐Mg3(HCOO)6 as an example, a good linear correlation between Areaguest/Areaframework (i. e., the integrated area of guest and framework 13C NMR signals) and guest loading can be observed for several representative molecules such as benzene, tetrahydrofuran (THF), and 1,4‐dioxane, clearly revealing the feasibility of CP quantification approach. The effects of guest molecule and corresponding residual mobility on the CP quantification are further discussed by varying the geometry and size of guest molecules. This methodology thus provides an effective and irreplaceable route to evaluate the adsorption performance of porous materials in‐depth, especially for liquid‐phase adsorption and gas‐phase adsorption in which the capillary condensation is not negligible.
The Transition from Alchemical to Modern Chemical Symbolism: from Bergman and Guiton de Morveau to Hassenfratz and Adet, Higgins, Richter, Dalton, and Berzelius
Authors: Wentrup Curt 
Published: April 2024

AbstractThe alchemical concepts of chemical symbolism, nomenclature, and affinity underwent fundamental changes between the 1770s and the 1820s, roughly simultaneously with the Chemical Revolution (ca. 1772–89), i. e. the replacement of the phlogiston theory with Lavoisier's New Chemistry. Using the old, alchemical symbols, Bergman devised a system of formulas to describe virtually all known inorganic chemistry, and he influenced Guiton de Morveau's Mémoire sur les Dénominations Chimiques, and the subsequent Méthode de nomenclature. Hassenfratz and Adet devised a new artificial sign language which, however, was too complicated and unintuitive to gain widespread acceptance. Bergman refined the concept of affinity, but his belief in phlogiston rapidly made the system obsolete. Wenzel realized that the dissolution of metals in acids is not just a question of affinity but rather of concentration, and he and Berthollet separately formulated early versions of the Law of Mass Action thereby making attempts to quantify affinity redundant. Richter formulated a principle that became known as the Law of Equivalent Proportions, describing acid‐base reactions and double decompositions of salts, but continuing to use Bergman‐style alchemical formulas. Only John Dalton's atomic theory with little globules denoting atoms and their combination into molecules made a definite break with the alchemical symbols.
DNA metabarcoding reveals the seasonal variation of dietary composition of Taihangshan macaque (Macaca mulatta tcheliensis), Jiyuan, north China
Authors: Zhou Yanyan , Liu Chunbo , Tian Jundong , Shao Qi , Lu Jiqi 
Published: April 2024

AbstractDietary analysis in wildlife is fundamental for understanding their flexible response to seasonal changes and developing effective conservation management measures. Taihangshan macaque (Macaca mulatta tcheliensis) is the northernmost population of rhesus macaque, currently only distributed in the southern Mt. Taihangshan area. This area belongs to a semi‐arid region resulting in limited plant food availability for Taihangshan macaques, with seasonal variation. Herein, we used a chloroplast trnL DNA metabarcoding approach to identify the plant diet diversity and composition from 100 fecal samples of Taihangshan macaque in four seasons (spring, summer, autumn, and winter) from 2020 to 2021. The results revealed that (1) a total of 48 distinct families, 88 genera, and 52 species within the 105 food items that were consumed by Taihangshan macaques throughout the year; (2) the diversity of food items exhibited significant differences across the four seasons; (3) Rosaceae, Rhamnaceae, Fagaceae, and Poaceae are the preferential food items for Taihangshan macaques and have different relative abundances, fluctuating with seasonal variation. DNA metabarcoding can expand our understanding of the repertoire of food items consumed by Taihangshan macaques by detecting some consumed food items in this population that were not yet discovered using traditional methods. Therefore, the integrative results from traditional methods and DNA metabarcoding can provide a fundamental understanding of dietary composition to guide the conservation management of Taihangshan macaques.
Inhibition of gut digestive proteases by cyanobacterial diets decreases infection in a Daphnia host–parasite system
Authors: Sánchez Kristel F. , von Elert Eric , Monell Kira , Calhoun Siobhan , Maisha Aniqa , McCreadie Paige , Duffy Meghan A. 
Published: April 2024

AbstractSecondary metabolites produced by primary producers have a wide range of functions as well as indirect effects outside the scope of their direct target. Research suggests that protease inhibitors produced by cyanobacteria influence grazing by herbivores and may also protect against parasites of cyanobacteria. In this study, we asked whether those same protease inhibitors produced by cyanobacteria could also influence the interactions of herbivores with their parasites. We used the Daphnia‐Metschnikowia zooplankton host‐fungal parasite system to address this question because it is well documented that cyanobacteria protease inhibitors suppress trypsin and chymotrypsin in the gut of Daphnia, and because it is known that Metschnikowia infects via the gut. We tested the hypothesis that Daphnia gut proteases are necessary for Metschnikowia spores to be released from their asci. We then also tested whether diets that decrease trypsin and chymotrypsin activity in the guts of Daphnia lead to lower levels of infection. Our results show that chymotrypsin promotes the release of the fungal spores from their asci. Moreover, a diet that strongly inhibited chymotrypsin activity in Daphnia decreased infection levels, particularly in the most susceptible Daphnia clones. Our results support the growing literature that cyanobacterial diets can be beneficial to zooplankton hosts when challenged by parasites and uncover a mechanism that contributes to the protective effect of cyanobacterial diets. Specifically, we demonstrate that host chymotrypsin enzymes promote the dehiscence of Metschnikowia spores; when cyanobacteria inhibit the activity of chymotrypsin in hosts, this most likely traps the spore inside the ascus, preventing the parasite from puncturing the gut and beginning the infection process. This study illustrates how secondary metabolites of phytoplankton can protect herbivores against their own enemies.
In vitro human cell culture models in a bench‐to‐bedside approach to epilepsy
Authors: Danačíková Šárka , Straka Barbora , Daněk Jan , Kořínek Vladimír , Otáhal Jakub 
Published: April 2024

AbstractEpilepsy is the most common chronic neurological disease, affecting nearly 1%–2% of the world's population. Current pharmacological treatment and regimen adjustments are aimed at controlling seizures; however, they are ineffective in one‐third of the patients. Although neuronal hyperexcitability was previously thought to be mainly due to ion channel alterations, current research has revealed other contributing molecular pathways, including processes involved in cellular signaling, energy metabolism, protein synthesis, axon guidance, inflammation, and others. Some forms of drug‐resistant epilepsy are caused by genetic defects that constitute potential targets for precision therapy. Although such approaches are increasingly important, they are still in the early stages of development. This review aims to provide a summary of practical aspects of the employment of in vitro human cell culture models in epilepsy diagnosis, treatment, and research. First, we briefly summarize the genetic testing that may result in the detection of candidate pathogenic variants in genes involved in epilepsy pathogenesis. Consequently, we review existing in vitro cell models, including induced pluripotent stem cells and differentiated neuronal cells, providing their specific properties, validity, and employment in research pipelines. We cover two methodological approaches. The first approach involves the utilization of somatic cells directly obtained from individual patients, while the second approach entails the utilization of characterized cell lines. The models are evaluated in terms of their research and clinical benefits, relevance to the in vivo conditions, legal and ethical aspects, time and cost demands, and available published data. Despite the methodological, temporal, and financial demands of the reviewed models they possess high potential to be used as robust systems in routine testing of pathogenicity of detected variants in the near future and provide a solid experimental background for personalized therapy of genetic epilepsies.Plain Language SummaryEpilepsy affects millions worldwide, but current treatments fail for many patients. Beyond traditional ion channel alterations, various genetic factors contribute to the disorder's complexity. This review explores how in vitro human cell models, either from patients or from cell lines, can aid in understanding epilepsy's genetic roots and developing personalized therapies. While these models require further investigation, they offer hope for improved diagnosis and treatment of genetic forms of epilepsy.
UAV‐SfM‐based field quantification of barchan dune celerity and morphodynamics in Gonghe Basin
Authors: Shao Mei , Luo Wanyin , Che Xuehua , Hesp Patrick A. , Bryant Robert G. 
Published: April 2024

AbstractBarchan dunes do not often coexist with grasslands. However, in Gonghe Basin, north‐eastern part in Qinghai‐Tibetan Plateau (QTP), China, many barchan dunes are distributed on the grassland at high altitude. Identifying celerity and morphodynamics of barchan dunes and exploring the interaction between barchans and grassland landscape can help us better understand aeolian system sand mitigate damages. In this work, we tracked dune celerity and observed three‐dimensional changes of symmetrical and asymmetrical barchan dunes in Ertala based on high‐resolution UAV‐SfM reconstruction in short‐term monitoring and discussed the factors influencing dune celerity and deformation at high altitude. The results revealed that the barchan dunes are highly mobile with an average celerity of 0.85 m/M for the whole study area. Based on observations of dune morphology and dynamics, we found the following: (1) The dune deformation degree in a short time is not large but is widespread, especially in the elongated arm of asymmetric dune. The deformation of symmetric dune is symmetrical, whereas that of dune with extended horn is asymmetrical; (2) the sand supply, vegetation and airflow at low air density all influence the celerity and deformation degree in the development of barchan dunes; (3) the asymmetric airflow and sediment supply are important cause of dune asymmetry. The above results help us understand the deformation of barchan dune from the three‐dimensional, especially the difference reflected by the symmetry of barchan dune at high altitude.
Evapotranspiration and crop coefficient of ‘Kent’ mango in an important fruit‐growing hub in Brazil
Authors: da Silva Marcelo José , de Moura Magna Soelma Beserra , Carvalho Herica Fernanda de Sousa , dos Santos Cloves Vilas Boas , Leitão Mário de Miranda Villas Boas Ramos , Campeche Luis Fernando de Souza Magno , da Silva Thieres George Freire 
Published: April 2024

AbstractThe ‘Kent’ mango is one of the main cultivars produced in the São Francisco valley. However, due to a lack of data, water management was carried out using coefficients from the Tommy Atkins cultivar. Thus, aiming to achieve greater water management efficiency, the aim of this study was to evaluate the growth, radiation and energy balance, evapotranspiration and coefficients of the ‘Kent’ mango in the lower‐middle São Francisco valley in Brazil. The study was conducted in an orchard over two harvests between 2017 and 2018. The radiation and energy balance, evapotranspiration (ETc) and crop coefficients (Kc) of the mango were estimated from micrometeorological data. The mean reference evapotranspiration (ET0) and ETc values were 5.47 and 4.40 mm day−1 (vegetative growth, VG), 4.42 and 4.29 mm day−1 (floral induction, FI), 4.08 and 3.48 mm day−1 (floral induction + flowering, FI + FL), 4.51 and 3.63 mm day−1 (fruit drop, FD) and 6.09 and 4.46 mm day−1 (formation fruit + maturation fruit phase, FF + MF). Under the climate conditions of the São Francisco valley, Kc values of 0.80, 0.97, 0.85, 0.80 and 0.74 are recommended for the ‘Kent’ mango during the VG, FI, FI + FL, FD and FF + MF phases, respectively.
Utility value of improving writing skills for adult basic education students
Authors: Martinez Jennifer , Greenberg Daphne , Puranik Cynthia , Braasch Jason Lawrence , Traga Philippakos Zoi A. , MacArthur Charles A. , Miller Christine 
Published: April 2024

AbstractMotivational research identifies utility value, or the importance of a learning task to future goals, as central to motivation to learn. This study analyzed survey data (N = 86) collected from adult literacy learners to examine their utility value of writing improvement in grammar and spelling skills, word processing skills, and planning, drafting, and revising skills. Findings revealed that participants had a high utility value of improving writing in all three skill areas and possessed a variety of underlying motivations, including obtaining further education, seeking future employment, and personal reasons. Participants' age, educational attainment, and reading levels showed relationships with utility value of improving grammar and spelling skills, and age showed an additional relationship to utility value of improving word processing skills. This work extends research on motivation in this population and supports the application of expectancy‐value theory to both adult motivation and writing motivation.