bluuebunny/crossref_metadata_2025_split huggingface dataset:
Transitional Care Models for Stroke Survivors to Improve Quality of Care through Bridging the Care Gap from Hospital to Home: A State of Art Review
Authors: Paudel Kalpana , Banstola Ratna Shila 
Published: April 2024

Introduction : Stroke is a life threatening medical emergency that occurs suddenly and impact greatly in all aspect of an individual’s normal life since the early stage to long term. Various types of transitional care models are using by Health systems to improve care transition among stroke patients. Aims:
This paper aims to explore the existing transitional care models used to improve the quality of care and patient’s outcome among stroke survivors.
Methods: An Integrated review was conducted of empirical literature available in PubMed, Google Scholar, ProQuest, and NepJol by June 20, 2022 to identify studies of hospital to home care transitions of stroke patients with quality of care as the primary outcome.
Results: There are 6 main types of transitional care model which focused on care transition for stroke survivors: 1) Naylor’s Transitional Care Model (TCM), 2) Coleman’s Care Transition Interventions (CTI), 3) Project Re-engineered Discharge (project RED), 4) Better Outcomes by Optimizing Safe Transition (Project Boost), 5) Enhanced Discharge Planning Program and 6) Comprehensive Post- Acute Stroke Services (COMPASS). Although, all models are differing by design, each of the models can provide a framework for managing health conditions from hospital to home settings in collaboration with the client and his/her family. Hence, the transitional care Models are effective in bridging the care gap between hospital to home and improve the quality of health care and patient outcomes among stroke survivors.
COVID-19 and Nursing Care of Ophthalmic Patients During Pandemic
Authors: Bhattarai Shanjeev , Gautam Adhikari Pragati 
Published: April 2024

Background: The corona virus, a novel, enveloped single stranded RNA virus (sarscOv-2) which has mainly affected respiratory system with life threatening results. The SARS-CoV-2 has been detected in several body fluids including tear and discharge of patients suffering from conjunctivitis. The aim of this paper is to explore the nursing care of person with ophthalmic problems.
Methods: A literature review was conducted using data based of Google scholar, Google, Pubmed, Medline since 2015-2023.
Results: An ophthalmic nurse can play a key role in teaching a patient and their attendants about general eye care and protection of vision during COVID-19 monitoring the patient’s condition, as well as ophthalmic instruments after it’s use have been are two main responsibilities of the nurse working in the ophthalmic units. Nurses also have responsibilities to maintain the safe and clean working environment of the unit, making the environment clean and safe.
Conclusion: The environment of the eye ward must be clean, safe and free from organism. A nurse should warn the patients not to touch or rub the eyes and dressings or eye shields with unprotected hand during this COVID-19 pandemic.
A Review of the Impact of Nigerian Tourism Development in the Preservation of Arts and Culture
Authors: Adekunle Quawih  
Published: April 2024

This study investigates the responsibilities that museums play in conserving art and culture. It argues that museums should be responsible for making historic values accessible and understandable to all visitors, rather than depending simply on traditional item displays. Museums provide opportunities for global travelers to learn about different perspectives on the importance of history and how to preserve their heritage. The method used in this research is qualitative. Research was carried out by compiling and analyzing existing studies. The obstacles to the preservation of art and culture, and how can research help museums use their physical, intentional forms to produce visitor experiences that are meaningful, active, ethical, and continuous, as well as a visible representation of tourism in Nigeria served as the focal points of this paper’s research. The findings support the dual functions of museums, preserving our artistic heritage and acting as a significant source of revenue to support the travel and tourist industry. In addition to significantly increasing global income, tourism is now a key factor in the expansion of economies across the world. The primary rationale behind the growth of tourism in many nations worldwide is often its capacity to have a favorable economic impact through the lens of modern heritage values and ethics. The findings of this research reflect the intricate ways by which tourism and culture are tightly correlated.
Comparing Nutritional Status of Children in Nuclear and Joint Families: A Cross-Sectional Study in Karachi, Pakistan
Authors: Samrina Hafiza Syeda , Kalsoom Eiman , Rahoojo Riaz Hussain 
Published: April 2024

Background: Child stunting and underweight are worldwide issues that may be connected to family structure. This research examined family type (nuclear vs. joint), women's empowerment, and child nutrition in Karachi, Pakistan.
Methods: A cross-sectional research included 450 under-5s and their moms from healthcare settings. Child nutrition and mother empowerment were examined using standardized instruments. Nutritional outcomes, empowerment, and child stunting/underweight were examined across household types.
Results: Compared to children from nuclear families (stunting: 32.9%, 95% CI: 27.0-39.3; underweight: 15.6%, 95% CI: 10.9-21.4), children from joint families showed substantially reduced rates of underweight (32.9%, 95% CI: 27.0-39.3) and stunting (22.7%, 95% CI: 17.8-28.3) (p = 0.02 for both). In comparison to nuclear families (12.9%, 95% CI: 8.9-17.7), the slightly higher overweight prevalence in joint families (14.7%, 95% CI: 10.3-19.8) was not statistically significant (p = 0.51). Remarkably, greater maternal empowerment ratings were substantially linked to a decreased risk of stunting (OR = 0.92, 95% CI: 0.87-0.98, p = 0.01) and underweight (OR = 0.92, 95% CI: 0.87-0.98, p = 0.01) in children, independent of the type of household.
Conclusion: This research demonstrates that combined family structure may minimize stunting and underweight. Women's empowerment also improved child nutrition in both families. Further study is required to understand these results' mechanisms and long-term effects.
Keywords: Child malnutrition, Family structure, Women's empowerment, Nutritional status, Karachi, Pakistan
Impact of the COVID-19 Pandemic on the Professional Training of Student Nurse from Universities in Ghana.
Authors: Arthur-Mensah R. Arthur-Mensah , Kyei A. A. Kyei 
Published: April 2024

Introduction: On December 31, 2019, WHO was informed of cases of pneumonia of unknown cause in some patients in Wuhan City, Hubei Province, China (WHO, 2020). Viral testing detected a novel coronavirus disease in these patients. Subsequently, the disease progressed into a global pandemic. To curb the spread of the disease in Ghana, the government announced a series of comprehensive measures, including the closure of all schools; Basic, Junior High, Senior High and Universities. The health care workforce-in-training have been affected by this move, including student nurses who were just about to write their licensure examinations and continuing students.
Objectives: This study therefore sought to investigate the impact of the COVID-19 pandemic on the professional training of student nurses from universities in Ghana.
Methodology: A cross-sectional study using a descriptive design was used to include student nurses from various universities in Ghana.
Results: The major impact of the pandemic on the student nurses was the online learning medium which was adopted as the means of teaching and learning in the period. The students said that the online medium of instruction was deficient of the standard method the nursing education program is to be tutored. Results showed a significant difference (P=0.014) of the impact of the pandemic among the student nurses from the various universities.
Conclusion: The nursing profession continues to attract those who strive to help mankind, even in its darkest hours. Student nurses are no exception, as evidenced by their choice and determination to study and practice nursing.
Patients’ Satisfaction with Male Nurses: Evidence from a Teaching Hospital in Ghana.
Authors: Arthur-Mensah R. Arthur-Mensah , Tsey F. E. Tsey , Adu-Gyamfi P. K. T. Adu-Gyamfi , Tetteh-Ahinakwa L. Tetteh-Ahinakwa , Kyei A. A. Kyei 
Published: April 2024

Objectives: In an effort to contribute to the literature on improving nursing care and patient satisfaction, this study sought to evaluate patients’ satisfaction and identify their priorities among the service quality dimensions from the nursing care received from male versus female nurses in Ghana’s premier and largest tertiary teaching hospital, the Korle Bu Teaching Hospital (KBTH).
Methodology: The study adopted a quantitative research approach with a comparative study design. The study sites comprised of the accident and orthopaedic, chest, medical and surgical departments at KBTH. A total of 407 in-patients who had been on admission at these departments for at least 4 days and 4 nights were included in the study. The SERVQUAL model was adapted in measuring patient satisfaction.
Results: Patients were more satisfied with the health care they received from the male nurses than the female nurses. Overall aggregate score for male nurses was 860.00 with a mean (SD) of 4.20 (±0.57). Overall aggregate score for female nurses was 800.00 with a mean (SD) of 3.96 (±0.64). The independent sample t test showed a significant difference ( in the mean values from the two groups. CFA of the model showed in order of priority that, responsiveness, assurance, empathy, reliability and tangibility were significant contributors to patients’ satisfaction.
Conclusion: By integrating the dimensions of service quality into their services, hospitals in Africa could benefit from improved quality of service, patient retention and loyalty, market share and profitability.
GPR27 expression correlates with prognosis and tumor progression in gliomas
Authors: Cai Changcheng , Hu Libo , Wu Ke , Liu Yinggang 
Published: April 2024

Backgrounds
Glioma is a highly aggressive type of brain tumor, and its prognosis is still poor despite recent progress in treatment strategies. G protein-coupled receptor 27 (GPR27) is a member of the G protein-coupled receptor family and has been reported to be involved in various cellular processes, including tumor progression. Nevertheless, the clinical potential and tumor-related role of GPR27 in glioma remain unknown. Here we aimed to explore the function and role of GPR27 in gliomas.

Methods
In the current study, we evaluated the expression and clinical significance of GPR27 in gliomas using data from The Cancer Genome Atlas (TCGA) datasets. We also conducted cellular experiments to evaluate the functional role of GPR27 in glioma cell growth.

Results
We found that GPR27 expression level was closely associated with disease status of glioma. Of note, GPR27 was negatively correlated with WHO grade, with grade IV samples showing the lowest GPR27 levels, while grade II samples showed the highest levels. Patients with IDH mutation or 1p/19q co-deletion exhibited higher GPR27 levels. In addition, lower GPR27 levels were correlated with higher death possibilities. In cellular experiments, we confirmed that GPR27 inhibited glioma cell growth.

Conclusions
Our results indicate that GPR27 may function as a potential prognostic biomarker and therapeutic target in gliomas. Further studies are needed to illustrate the signaling mechanism and clinical implications of GPR27 in gliomas.
Effectiveness of gamification in nursing degree education
Authors: Sanz-Martos Sebastián , Álvarez-García Cristina , Álvarez-Nieto Carmen , López-Medina Isabel M. , López-Franco María Dolores , Fernandez-Martinez Maria E. , Ortega-Donaire Lucía 
Published: April 2024

Background
Previous research in nursing has found favorable results from the use of teaching methodologies alternative to lectures. One of the complementary methodologies used for university teaching is gamification, or the inclusion of game elements, creating a dynamic learning environment that allows the acquisition of knowledge and the development of other skills necessary for nursing students. The purpose of this study was to evaluate the effect of a gamification session on student satisfaction and knowledge scores in nursing students in simulated laboratory practice.

Methods
A pre-post quasi-experimental study was conducted with 122 students from the nursing degree program who participated in the research. The evaluation consisted of four sessions of three hours each. In two sessions, participants were trained through a vertical methodology, by means of theoretical training provided by teaching staff, and two hours of clinical simulation, where the students were able to practice the techniques on professional simulators. At the other two sessions, participants received an explanation of the theoretical aspects of the session, one hour of clinical simulation, and one hour of gamification, in which they had to pass tests based on the performance of practical activities on the subject of the session. At the end of the gamification session, all the participants received a certificate as winners of the “nursing game”.

Results
There was an improvement in the satisfaction and the knowledge level in the gamification sessions. Both were statistically significant (P < 0.001). There was an improvement in the items related to the development of critical thinking and the mobilizing concepts from theory to practice in the gamification sessions.

Conclusion
The intervention was effective in improving the satisfaction of the sessions received and in knowledge development.
Isolation and Characterization of Heavy Metal-Tolerant Bacterial Isolates from Industrial Effluents in Uttar Pradesh, India
Authors: Gangwar Shikha , Tripathi Vijay , Verma Om Prakash 
Published: April 2024

Industrial activities over the past century have significantly increased human exposure to pollutants such as heavy metals. Industrial emissions of heavy metals, which are carcinogenic, mutagenic and toxic, contaminate natural water supplies and the agricultural environment. Due to the high concentration of heavy metals in industrial effluents, the bacteria present there naturally develop resistance to heavy metals. The aim of this study is to isolate and characterize bacteria resistant to heavy metal, lead (Pb), copper (Cu), chromium (Cr), cadmium (Cd), and nickel (Ni) from sites contaminated by industrial effluents in Uttar Pradesh, India. A total of 58 bacterial isolates were isolated from 9 samples according to their various morphological parameters and 32 isolates were found positive for all heavy metals, which revealed that samples contained metal-resistant bacterial diversity. Two isolates were identified up to species level based on their physiological, biochemical and molecular characterization as Comamonas testosteroni (S4C1) and Bacillus cereus (S5C3). Both isolates are highly resistant to lead (Pb), copper (Cu), chromium (Cr), cadmium (Cd), and nickel (Ni) and they show different MICs against the above heavy metals at different levels. A growth experiment showed that the presence of heavy metals concentration had no discernible impact on the growth rate among the isolates. Gel analysis showed interesting patterns of protein expression were observed in the presence of various heavy metals. MALDI-TOF analysis found that specific proteins (S layer protein, F0F1ATP synthase subunit b, Flagellin, 50S ribosomal protein L4, Molecular chaperone) were overexpressed in the presence of heavy metals. As a result, identifying the heavy metal resistance bacteria and their proteins study could be useful as a preliminary investigation for the development of prospective bioremediation agents of potentially hazardous waste treatment technology.
Novel Sol–Gel Synthesis of Acidic MgF2−x(OH)x Materials
Authors: Wuttke Stefan , Coman Simona M. , Scholz Gudrun , Kirmse Holm , Vimont Alexandré , Daturi Maro , Schroeder Sven L. M. , Kemnitz Erhard 
Published: November 2008

AbstractNovel magnesium fluorides have been prepared by a new fluorolytic sol–gel synthesis for fluoride materials based on aqueous HF. By changing the amount of water at constant stoichiometric amount of HF, it is possible to tune the surface acidity of the resulting partly hydroxylated magnesium fluorides. These materials possess medium‐strength Lewis acid sites and, by increasing the amount of water, Brønsted acid sites as well. Magnesium hydroxyl groups normally have a basic nature and only with this new synthetic route is it possible to create Brønsted acidic magnesium hydroxyl groups. XRD, MAS NMR, TEM, thermal analysis, and elemental analysis have been applied to study the structure, composition, and thermal behaviour of the bulk materials. XPS measurements, FTIR with probe molecules, and the determination of N2/Ar adsorption–desorption isotherms have been carried out to investigate the surface properties. Furthermore, activity data have indicated that the tuning of the acidic properties makes these materials versatile catalysts for different classes of reactions, such as the synthesis of (all‐rac)‐[α]‐tocopherol through the condensation of 2,3,6‐trimethylhydroquinone (TMHQ) with isophytol (IP).
Three‐Dimensional Database Mining Identifies a Unique Chemotype that Unites Structurally Diverse Botulinum Neurotoxin Serotype A Inhibitors in a Three‐Zone Pharmacophore
Authors: Hermone Ann R. , Burnett James C. , Nuss Jonathan E. , Tressler Lyal E. , Nguyen Tam L. , Šolaja Bogdan A. , Vennerstrom Jonathan L. , Schmidt James J. , Wipf Peter , Bavari Sina , Gussio Rick 
Published: November 2008

AbstractA search query consisting of two aromatic centers and two cationic centers was defined based on previously identified small molecule inhibitors of the botulinum neurotoxin serotype A light chain (BoNT/A LC) and used to mine the National Cancer Institute Open Repository. Ten small molecule hits were identified, and upon testing, three demonstrated inhibitory activity. Of these, one was structurally unique, possessing a rigid diazachrysene scaffold. The steric limitations of the diazachrysene imposed a separation between the overlaps of previously identified inhibitors, revealing an extended binding mode. As a result, the pharmacophore for BoNT/A LC inhibition has been modified to encompass three zones. To demonstrate the utility of this model, a novel three‐zone inhibitor was mined and its activity was confirmed.
Effect of Polymer Composition and Water Content on Proton Conductivity in Vinyl Benzyl Phosphonic Acid—4‐Vinyl Pyridine Copolymers
Authors: Jiang Fengjing , Kaltbeitzel Anke , Fassbender Birgit , Brunklaus Gunther , Pu Hongting , Meyer Wolfgang H. , Spiess Hans W. , Wegner Gerhard 
Published: November 2008

AbstractThe proton conductivities of poly(vinylbenzyl phosphonic acid) (PVBPA) homopolymer and its statistical copolymers with 4‐vinyl pyridine [poly(VBPA‐stat‐4VP)s] are comprehensively studied in this work. Temperature and composition‐dependent “dry” proton conductivities of the copolymers have been determined and the self‐condensation of phosphonic acid groups has been quantified. The results show that the intrinsic proton conductivities of poly(VBPA‐stat‐4VP)s and PVBPA are quite low at 150 °C and exhibit time‐dependent changes due to anhydride formation at elevated temperatures. The effect of polymer composition on proton conduction shows a minimum at a 1:1 molar ratio of proton donor and acceptor groups and is discussed on the basis of the pKa values of the electrolyte species. A trace amount of water significantly increases conductivity probably due to additional hydronium ion diffusion and water bridging effects. Water content and proton conductivities of poly(VBPA‐stat‐4VP)s are determined at different relative humidities. High amounts of water are absorbed at high humidities leading to high proton conductivities.magnified image
Discovery of phosphorylation motif mixtures in phosphoproteomics data
Authors: Ritz Anna , Shakhnarovich Gregory , Salomon Arthur R. , Raphael Benjamin J. 
Published: November 2008

Abstract
Motivation: Modification of proteins via phosphorylation is a primary mechanism for signal transduction in cells. Phosphorylation sites on proteins are determined in part through particular patterns, or motifs, present in the amino acid sequence.
Results: We describe an algorithm that simultaneously discovers multiple motifs in a set of peptides that were phosphorylated by several different kinases. Such sets of peptides are routinely produced in proteomics experiments.Our motif-finding algorithm uses the principle of minimum description length to determine a mixture of sequence motifs that distinguish a foreground set of phosphopeptides from a background set of unphosphorylated peptides. We show that our algorithm outperforms existing motif-finding algorithms on synthetic datasets consisting of mixtures of known phosphorylation sites. We also derive a motif specificity score that quantifies whether or not the phosphoproteins containing an instance of a motif have a significant number of known interactions. Application of our motif-finding algorithm to recently published human and mouse proteomic studies recovers several known phosphorylation motifs and reveals a number of novel motifs that are enriched for interactions with a particular kinase or phosphatase. Our tools provide a new approach for uncovering the sequence specificities of uncharacterized kinases or phosphatases.
Availability: Software is available at http:/cs.brown.edu/people/braphael/software.html.
Contact: aritz@cs.brown.edu; braphael@cs.brown.edu
Supplementary information: Supplementary data are available at Bioinformatics online.
Creation and categorization of knowledge in automotive components SMEs in India
Authors: Pillania Rajesh K. 
Published: November 2008

PurposeNew knowledge creation has gained currency in the global knowledge economy. It is important not only for big firms, but for small and medium size enterprises (SMEs) also. Indian automotive components sector is one of the fastest growing sectors of Indian economy and is dominated by SMEs. This research work aims to study the knowledge creation and categorization in SMEs in Indian automotive components sector.Design/methodology/approachThis paper uses a survey method to collect primary data to study knowledge creation and categorization in automotive components manufacturers.FindingsAmong various kinds of knowledge, knowledge about customers is given most importance. Though new knowledge creation is gaining importance, research and development spending as percentage of turnover are very low. International automotive components manufacturers have a better perception about knowledge creation compared to the prevalent view in Indian firms. In terms of relevance, latest and timeliness, Indian and international automotive components manufacturers pay little credence to the knowledge available through government institutions and industry associations. Industry associations and governments need to have a re‐appraisal of their practices and make their working more useful, fast and updated.Practical implicationsThis work has policy implications for government and industry associations. Corrective measures are suggested for industry associations and government bodies for contributing to knowledge creation and implementing knowledge management in organizations.Originality/valueFirst of its kind study in SMEs, particularly automotive components sector in India. It studies the current state of knowledge creation and categorization and suggests guidelines for improving knowledge creation in SMEs.