bluuebunny/crossref_metadata_2025_split huggingface dataset:
Preparation and properties of cationic waterborne polyurethane/acrylate for fluorine‐free water repellents
Authors: Jiang Yang , Wang Chuanli , Liu Meng , Gu Biao , Wang Xiao , Xu Changhai , Xiao Guowei , Miao Dagang , Du Jinmei 
Published: March 2024

AbstractIn this work, cationic waterborne polyurethane/acrylate (WPUA) was synthesized for water repellent in cotton fabrics to replace fluorine‐containing finishing agents with the concerns of ecosystems and human health. First, the tertiary amines monomers, N‐methyl diethanolamine, 3‐dimethylamine‐1, 2‐propylene glycol, N,N′‐bis (2‐hydroxyethyl)piperazine, were used as chain extenders to prepare waterborne polyurethane, respectively. Long‐chain octadecyl acrylate monomers were then grafted to the waterborne polyurethane by a self‐emulsifying method. The stable WPUA suspensions of positively charged latexes were obtained and could be finished on cotton fabrics via a simple pad‐curing process. The coated cotton fabrics were capable of repelling common liquids without any penetration, and the contact angles of the treated cotton fabrics could reach 150°. The WPUA latex films also exhibited good tensile mechanical properties and thermal dimensional stability. The cotton fabric coated with the WPUA showed good laundering durability, and its static water contact angle was still maintained at 142° even after 50 times washing. This work not only highlights the structural design and preparation but also provides a feasible strategy for fluorine‐free water repellency in cotton fabrics, which has great potential application prospects for a variety of fields.
Multifunctional flexible strain sensor based on three‐dimensional core‐shell structures of silver nanoparticles/natural rubber
Authors: Chen Zihao , Sun Jinyu , Zhan Ziwei , Yuan Yizhong , Tian Xiaohui , Jin Jie , Wu Wangbao , Ayikanbaier Kadier 
Published: March 2024

AbstractConventional wearables may pose a health risk by promoting the growth of bacteria on the skin's surface due to sweating or contamination. Here, a multifunctional strain‐sensing composite has been fabricated through the combination of highly elastic natural rubber (NR) with silver nanoparticles (AgNPs), which possess antimicrobial and electrical conductivity properties. A 3D core‐shell structure composed of AgNPs and NR microspheres effectively reduces the percolation threshold of the AgNPs conductive network. As a strain sensor, the composite film presents a wide sensing range (0%–970%), an exceptionally high gauge factor (GF) value (59.3), and favorable cycling stability (over 1500 cycles at 50%). Finally, the composite film also exhibits antibacterial and hydrophobic properties, indicating its potential for use in challenging environments.
Pure chitosan multifilament yarns made using a semi‐industrial pilot scale wet‐spinning process with ionic liquids
Authors: Kuznik Irina , Kruppke Iris , Pötzsch Hendrik Florian , Cherif Chokri 
Published: March 2024

AbstractThe ionic liquid 1‐ethyl‐3‐methyl‐imidazolium acetate (EMIMOAc) is used to develop a wet‐spinning process for the manufacturing of chitosan multifilament yarns on a semi‐industrial pilot scale. Commercial chitosans of different qualities, properties, and deacetylation degree ≤85% are used to prepare of spinning dopes with solids content of 6.0–8.5 wt.% using EMIMOAc as a solvent. The viscometric properties are characterized by rheological tests. The manufacturing of the pure chitosan multifilament yarns of different fineness and filament count from the prepared spinning dopes is performed on a pilot wet‐spinning plant. The obtained yarn properties are evaluated by optical (scanning electron microscope, light microscope), structural (infrared spectroscopy, X‐ray diffraction), and textile‐physical characterization. Chitosan multifilament yarns with high performance, tenacities of ~20–26 cN tex−1 and textile processability in weaving, knitting and braiding processes are manufactured in this work.
Morpholinodiazenyl chalcone blocks influenza A virus capsid uncoating by perturbing the clathrin‐mediated vesicular trafficking pathway
Authors: Thottasseri Ahammed A. , Kaur Gaganpreet , Ramesh Deepthi , Banerjee Indranil , Kannan Tharanikkarasu 
Published: March 2024

AbstractInfluenza A virus (IAV) is a highly contagious respiratory pathogen that significantly threatens global health by causing seasonal epidemics and occasional, unpredictable pandemics. To identify new compounds with therapeutic potential against IAV, we designed and synthesized a series of 4′‐morpholinodiazenyl chalcones using the molecular hybridization method, performed a high‐content screen against IAV, and found that (E)‐1‐{4‐[(E)‐morpholinodiazenyl]phenyl}‐3‐(3,4,5‐trimethoxyphenyl)prop‐2‐en‐1‐one (MC‐22) completely neutralized IAV infection. While MC‐22 allowed IAV to successfully internalize into the cell and fuse at the acidic late endosomes, it prevented viral capsid uncoating and genome release. Since IAV majorly utilizes clathrin‐mediated endocytosis (CME) for cellular entry, we examined whether MC‐22 had any effect on CME, using nonviral cargoes that enter cells via clathrin‐dependent or ‐independent pathways. Although MC‐22 showed no effect on the uptake of choleratoxin B, a cargo that enters cells majorly via the clathrin‐independent pathway, it significantly attenuated the clathrin‐dependent internalization of both epidermal growth factor and transferrin. Cell biological analyses revealed a marked increase in the size of early endosomes upon MC‐22 treatment, indicating an endosomal trafficking/maturation defect. This study reports the identification of MC‐22 as a novel CME‐targeting, highly potent IAV entry inhibitor, which is expected to neutralize a broad spectrum of viruses that enter the host cells via CME.
I'm the same, I'm the same, I'm trying to change: Investigating the role of human information behavior in view change
Authors: McKay Dana , Makri Stephann , Gutierrez‐Lopez Marisela , Porlezza Colin , Macfarlane Andrew , Cooper Glenda , Missaoui Sondess 
Published: March 2024

AbstractInformation is powerful; it can influence peoples' views and, in turn, their behavior. Much recent research and discussion on the role information plays in view change has focused on filter bubbles, echo chambers and misinformation and how they might influence what people think and how they act. However, no prior work has focused specifically on understanding the human information behavior (HIB) that drives and facilitates view change. We report findings from interviews with 18 people who recently changed views on issues they considered important. We found a tight symbiotic relationship between HIB and view change; passive information encountering sparked change, often spurring follow‐up active seeking and verification which progressed the change to a “point of no return,” supported making the change and reinforced the decision to change. When shared, information that contributed to the change sometimes sparked changes in others (as did expressing or debating the change), serving as an information encounter that perpetuated a cycle of HIB and view change. This understanding of the integral role of HIB in view change can inform policy and systems design to promote view change autonomy and a broader research agenda of understanding HIB to support democratic principles and values.
Investigating implicit emotion processing in autism spectrum disorder across age groups: A cross‐modal emotional priming study
Authors: Leung Florence Y. N. , Stojanovik Vesna , Jiang Cunmei , Liu Fang 
Published: March 2024

AbstractCumulating evidence suggests that atypical emotion processing in autism may generalize across different stimulus domains. However, this evidence comes from studies examining explicit emotion recognition. It remains unclear whether domain‐general atypicality also applies to implicit emotion processing in autism and its implication for real‐world social communication. To investigate this, we employed a novel cross‐modal emotional priming task to assess implicit emotion processing of spoken/sung words (primes) through their influence on subsequent emotional judgment of faces/face‐like objects (targets). We assessed whether implicit emotional priming differed between 38 autistic and 38 neurotypical individuals across age groups as a function of prime and target type. Results indicated no overall group differences across age groups, prime types, and target types. However, differential, domain‐specific developmental patterns emerged for the autism and neurotypical groups. For neurotypical individuals, speech but not song primed the emotional judgment of faces across ages. This speech‐orienting tendency was not observed across ages in the autism group, as priming of speech on faces was not seen in autistic adults. These results outline the importance of the delicate weighting between speech‐ versus song‐orientation in implicit emotion processing throughout development, providing more nuanced insights into the emotion processing profile of autistic individuals.
Child behavior problems and parental psychological distress in Chinese families of children with autism: The putative moderating role of parental social support and cultural values
Authors: Liu Wenyuan , Thompson Paul A. , Gray Kylie M. , Hastings Richard P. 
Published: March 2024

AbstractThe wellbeing of parents of children with autism residing in mainland China remains understudied. We aimed to examine whether and how parental perceived social support, individualism, and collectivism acted together to moderate the relationships between child behavior problems and parental psychological distress in Chinese parents of children with autism. With convenience and snowball sampling, data on 268 primary caregiver parents of children with autism were collected from an online cross‐sectional survey. Linear regression analysis indicated that child behavior problems were significantly associated with increased psychological distress in Chinese parents of children with autism. There was no evidence to support the stress‐buffering model of social support in moderation analysis of the association between child behavior problems and parental psychological distress. Nonetheless, increased social support was associated with lower levels of parental psychological distress. Moderated moderation analyses did not support a role for individualism or collectivism as a moderator of the putative buffering role of social support. However, there was evidence that parental individualism was associated with increased parental psychological distress. Our findings highlight that child behavior problems are a robust correlate of parental psychological distress, and parental social support may act as a compensatory factor promoting less psychological distress rather than having a protective role. The role of social support and cultural values in the wellbeing of parents of children with autism in China requires additional exploration, including longitudinal research designs.
Delayed pipe replacement halves environmental impacts but quadruples water loss
Authors: Clayton Jonathan G. , Mejía‐Marchena Ricardo L. , Jiang Daqian , Terry Leigh G. 
Published: March 2024

AbstractScheduling pipe replacement is critical for water distribution systems (WDSs) when managing finances and water loss. WDS replacements are often delayed due to high immediate costs without considering long‐term environmental consequences. This study is the first to examine a real‐world WDS using a novel workflow transferrable to other WDSs that integrates GIS, hydraulic modeling, breakage prediction, and life cycle analysis to evaluate environmental impacts and water loss of five replacement schedules (25‐, 50‐, 75‐, 100‐, 150‐year intervals). Environmental impacts were reduced by half when replacement interval changed from 25 year to 150 years, yet volume of water leaked from the system quadrupled. Benefits plateaued beyond 50–75‐year replacement while water loss steadily increased. Lowering water loss through break management enabled one‐sixth pipe replacement without exceeding original leakage at 25‐year replacement. Results were robust to uncertainty parameters and assert the importance of equilibrating environmental impacts and water loss when designing pipe replacement frequency.
Lipases: market study and potential applications of immobilized derivatives
Authors: Bullo Giovanna Totti , Marasca Nicole , Almeida Francisco Lucas Chaves , Forte Marcus Bruno Soares 
Published: March 2024

AbstractThe enzyme market is growing constantly, and lipases, in their free and immobilized forms, constitute an important part of this market. This study aimed to analyze and discuss current market scenarios using data from the literature, focusing on lipases and the feasibility of their use in the immobilized form. It also compares the cost of biodiesel production using two commercial lipases: Eversa Transform 2.0 (free lipase) and Novozyme 435 (immobilized lipase). The results show that the European and North American enzyme markets are the most prominent worldwide, with Denmark and the USA as the major exporters and importers, respectively. Lipases can be used in a wide variety of fields, and immobilization brings many advantages to this enzyme class. Finally, we show the use of immobilized enzymes and lipases in biorefinery and food industries and carry out a comparative cost analysis to produce biodiesel using a free and immobilized lipase. We concluded that the enzyme market, in which lipases play an important role, is extensive, and that immobilized lipases seem to be excellent biocatalysts with feasible costs for industrial applications.
Mindfulness in education: Critical debates and pragmatic considerations
Authors: Lee Winky , McCaw Christopher T. , Van Dam Nicholas T. 
Published: March 2024

AbstractMindfulness has all but become a mainstay in modern education. Yet despite the incredible enthusiasm and increased application in schools, there remains significant divergence between advocates and critics. Advocates assert that mindfulness practice promotes individual and societal health and well‐being. Meanwhile, critics question the intention and the social and political implications of promoting these ancient practices in schools, arguing that the Buddhist ethics underlying mindfulness remain incompatible with the neoliberal ideology and instrumentalism of contemporary schooling. As mindfulness has been commodified, instrumentalised and used as a therapeutic tool for acute coping, its broader potential for human growth and development may be undermined. Furthermore, scholars caution that the fledging nature of mindfulness research leaves critical questions unanswered, especially the potential for adverse effects. The work herein examines these critiques, presenting three critical considerations for mindfulness in education, and articulates practical recommendations for educational leaders, policy makers and stakeholders. We aim to empower educators and others to make judgements about the promotion and integration of mindfulness into educational settings, considering context‐specific factors such as developmental needs and capacities, as well as recommendations to support effective and ethical practice of mindfulness in education.
Exposure‐based treatments for fear and reactivity to medical procedures: A systematic review of the literature with implications for research and practice
Authors: Abdel‐Jalil Awab , Baldwin Jillian N. , Leaf Justin B. 
Published: March 2024

AbstractThis systematic literature review following updated PRISMA guidelines investigated the application of exposure treatments to address phobias and highly reactive patterns associated with medical procedures. Through a search of APA PsycINFO followed by screening, 62 articles were identified spanning the years 1968–2021, encompassing a total of 715 participants and 11 medical procedures. Multiple variables were assessed across these articles, and common patterns were analyzed. The review reveals general trends within the field and offers valuable insights for future researchers and practitioners. Outcomes related to participants' proximity to receiving necessary medical care were recorded and discussed. Notably, to the authors' knowledge, this review appears to be the first systematic literature review focusing on the use of exposure treatments for addressing phobias related to medical procedures as a comprehensive category.
Fluorescence ‘turn‐off–on’ assays for neomycin sulphate and K+ ions with orange‐red fluorescent molybdenum nanoclusters
Authors: Sadhu Vibhuti Atulbhai , Jha Sanjay , Park Tae Jung , Kailasa Suresh Kumar 
Published: March 2024

AbstractFluorescent metal nanoclusters (MNCs) have found extensive application in recognizing molecular species. Here, orange‐red fluorescent Arg–A. paniculata–MoNCs were synthesized using Andrographis paniculata leaf extract, arginine as a ligand, and MoCl5 as a metal precursor. The Arg–A. paniculata–MoNCs complex exhibited a quantum yield (QY) of 16.91% and excitation/emission wavelengths of 400/665 nm. The synthesized Arg–A. paniculata–MoNCs successfully acted as a probe for assaying neomycin sulphate (NS) via fluorescence turn‐off and K+ ions via fluorescence turn‐on mechanisms, respectively. Moreover, the developed probe was effectively used to develop a cellulose paper strip‐based sensor for detection of NS and K+ ions. Arg–A. paniculata–MoNCs demonstrated great potential for sensing NS and K+ ions, with concentration ranges of 0.1–80 and 0.25–110 μM for NS and K+ ions, respectively. The as‐synthesized Arg–A. paniculata–MoNCs efficiently detected NS and K+ ions in food and biofluid samples, respectively.
The interlacing anticancer effect of pharmacologic ascorbate, chloroquine, and resveratrol
Authors: Makk‐Merczel Kinga , Varga Dóra , Hajdinák Péter , Szarka András 
Published: March 2024

AbstractCurrently, a diagnosis with KRAS mutant pancreatic ductal adenocarcinoma (PDAC) means a death warrant, so finding efficient therapeutic options is a pressing issue. Here, we presented that pharmacologic ascorbate, chloroquine and resveratrol co‐treatment exerted a synergistic cytotoxic effect on PDAC cell lines. The observed synergistic cytotoxicity was a general feature in all investigated cancer cell lines independent of the KRAS mutational status and seems to be independent of the autophagy inhibitory effect of chloroquine. Furthermore, it seems that apoptosis and necroptosis are also not likely to play any role in the cytotoxicity of chloroquine. Both pharmacologic ascorbate and resveratrol caused double‐strand DNA breaks accompanied by cell cycle arrest. It seems resveratrol‐induced cytotoxicity is independent of reactive oxygen species (ROS) generation and accompanied by a significant elevation of caspase‐3/7 activity, while pharmacologic ascorbate‐induced cytotoxicity shows strong ROS dependence but proved to be caspase‐independent. Our results are particularly important since ascorbate and resveratrol are natural compounds without significant harmful effects on normal cells, and chloroquine is a known antimalarial drug that can easily be repurposed.
Does combining analytical and synthetic knowledge benefit eco‐innovation? Evidence from Norway
Authors: Vai Faraimo Jay 
Published: March 2024

AbstractAnalytical or synthetic knowledge is widely considered beneficial for eco‐innovation (EI). For a firm, analytical and synthetic knowledge can be acquired externally through collaboration with various partners or generated internally through R&D and other internal firm activities. However, evidence supporting the assumption that both forms of knowledge are complementary and that “doing more of all” will benefit EI is unclear. We found that external analytical and synthetic knowledge and internal analytical and synthetic knowledge all positively affect EI, with internal analytical being the most prominent. However, combining analytical and synthetic knowledge may not be beneficial for EI. The interaction between analytical and external synthetic knowledge is generally substitutive. We found a particularly significant substitutive effect between internal analytical and internal synthetic knowledge, as well as between internal analytical and external synthetic knowledge. In short, we found little evidence of complementarity between analytical and synthetic knowledge, regardless of where it is acquired from. These findings advise caution to firm managers and policymakers who are considering strategies to combine different forms of knowledge from different sources to successfully achieve EI goals.
Human induced pluripotent stem cells‐derived liver organoids grown on a Biomimesys® hyaluronic acid‐based hydroscaffold as a new model for studying human lipoprotein metabolism
Authors: Roudaut Meryl , Caillaud Amandine , Souguir Zied , Bray Lise , Girardeau Aurore , Rimbert Antoine , Croyal Mikaël , Lambert Gilles , Patitucci Murielle , Delpouve Gaspard , Vandenhaute Élodie , Le May Cédric , Maubon Nathalie , Cariou Bertrand , Si‐Tayeb Karim 
Published: March 2024

AbstractThe liver plays a key role in the metabolism of lipoproteins, controlling both production and catabolism. To accelerate the development of new lipid‐lowering therapies in humans, it is essential to have a relevant in vitro study model available. The current hepatocyte‐like cells (HLCs) models derived from hiPSC can be used to model many genetically driven diseases but require further improvement to better recapitulate the complexity of liver functions. Here, we aimed to improve the maturation of HLCs using a three‐dimensional (3D) approach using Biomimesys®, a hyaluronic acid‐based hydroscaffold in which hiPSCs may directly form aggregates and differentiate toward a functional liver organoid model. After a 28‐day differentiation 3D protocol, we showed that many hepatic genes were upregulated in the 3D model (liver organoids) in comparison with the 2D model (HLCs). Liver organoids, grown on Biomimesys®, exhibited an autonomous cell organization, were composed of different cell types and displayed enhanced cytochromes P450 activities compared to HLCs. Regarding the functional capacities of these organoids, we showed that they were able to accumulate lipids (hepatic steatosis), internalize low‐density lipoprotein and secrete apolipoprotein B. Interestingly, we showed for the first time that this model was also able to produce apolipoprotein (a), the apolipoprotein (a) specific of Lp(a). This innovative hiPSC‐derived liver organoid model may serve as a relevant model for studying human lipopoprotein metabolism, including Lp(a).