bluuebunny/crossref_metadata_2025_split huggingface dataset:
Developing a Mobile Learning Virtual Nursing Diagnosis (VND) Media for Medical Surgical Nursing Course
Authors: Bustami  , Abdurrahman  , Wirda Hayati  , Erlangga Galih Zulva Nugroho  , Cut Mutiah  , Muhammad Nazar  
Published: March 2024

Link of Video Abstract: https://youtu.be/4zHCrIC1IGE

Background: The development of innovative and technology-aligned learning media is a necessary solution for nursing students. Students require access to interactive, practical, and easily accessible learning resources. An application that can facilitate students' learning in nursing diagnosis for surgical nursing, such as Virtual Nursing Diagnosis (VND), is needed. This study focuses on the development of the VND application specifically designed for the Surgical Nursing Care course.
Patients and methods: The research is a Research and Development (R&D) study involving 253 nursing students from Aceh Health Polytechnic. A needs analysis was conducted to identify the difficulties faced by students in applying nursing diagnoses to topics related to surgical nursing, particularly the cardiovascular system. Based on the findings of the needs analysis, it was discovered that students face difficulties in determining nursing problems. Therefore, the VND application was developed with features such as assessment forms, assessment tools, disease pathology, and nursing diagnoses. Additionally, the application is equipped with competency tests on interesting nursing cases that are user-friendly for students.
Results: The research results indicate that the VND application has received positive feedback from 253 students who have used it in real classroom environments. The application is user-friendly, efficient in performing nursing diagnoses, and provides available nursing case questions. VND application provides an interactive, innovative, and effective learning tool for understanding nursing diagnoses while enhancing accessibility and flexibility through mobile-based learning. The application equips students with the necessary skills to apply nursing diagnoses in real-world surgical medical practice.
Conclusion: the VND application significantly contributes to the development of nursing education. It not only improves understanding of nursing diagnoses but also provides an engaging and interactive learning experience. It is hoped that the use of the VND application in surgical nursing education can be an effective and innovative solution to enhance competency in applying nursing diagnoses in clinical practice.
Hypoalbuminemia in burn patients with COVID-19: a cross-sectional study
Authors: Noviana Heri , Saputro Iswinarno Doso , Handriani Ira 
Published: March 2024

Link of Video Abstract: https://youtu.be/onpoWqpxn5Q

Background: Burns contributes substantially to illness and death rates in underdeveloped nations. Hypoalbuminemia is a medical disorder that has been observed in both burn patients and individuals diagnosed with COVID-19. Hypoalbuminemia has been observed to exacerbate the severity of burn injuries and potentially COVID-19 infections. This retrospective study aimed to examine the disparity in hypoalbuminemia occurrence and its association with mortality among burn patients, specifically focusing on those infected with and without COVID-19.
Methods: The present investigation is a retrospective cross-sectional study examining the disparities in hypoalbuminemia occurrence and its association with mortality among burn patients with or without COVID-19. The study was conducted at Dr. Soetomo General Hospital in Surabaya, covering the time frame from March 2020 to December 2022.
Results: Among a cohort of 225 individuals who presented with acute phase burns, both with and without COVID-19, a total of 125 patients (57.1%) were seen to develop hypoalbuminemia during their treatment at Dr. Soetomo General Hospital between March 2020 and December 2022. This study found no statistically significant disparity in mean albumin levels and mortality outcomes between acute-phase burn patients with COVID-19 and those without COVID-19 who experienced hypoalbuminemia. Nevertheless, notable disparities (p<0.05) were seen in terms of age, length of stay (LOS), and severity of burns among hypoalbuminemia patients who were discharged from the hospital (KRS) for outpatient care and those who succumbed to their condition.
Conclusion: Our findings indicate no statistically significant disparity in albumin levels and mortality rates among burn patients, regardless of whether they are also diagnosed with COVID-19. Nevertheless, variables such as age, length of stay (LOS), and burn area exhibit notable variations in the outcome of death.
Research trends on the use of ultrasound as neuromodulation-based therapy, based on bibliometric analysis
Authors: Yurisaldi Arman , Setiobudi Tony , Sayyid Hashuro Muhammad Shiddiq 
Published: March 2024

Link of Video Abstract: https://youtu.be/3g92-Hr_5c0

Introduction: Ultrasound has seen a significant increase in use in neuromodulation-based therapy over the past decade due to technological advancements, enabling precise tissue ablation, clinical neuromodulatory brain stimulation, and targeted blood-brain barrier permeabilization. The bibliometric analysis reveals a growing body of literature focused on the utilization of low-intensity ultrasound (LI-US) and high-intensity focused ultrasound (HIFUS) in the field of neuromodulation. Ultrasonography has potential applications in treating neurological and psychiatric illnesses like neuropathic pain, epilepsy, and treatment-resistant mental illness, but further investigation is needed to understand mechanisms and safety considerations. The use of bibliometric analysis can effectively identify common research patterns and highlight advancements in this specific academic field. Research indicates that ultrasound-based neuromodulation approaches may offer novel therapeutic interventions with enhanced efficacy and safety in treating various neurological and mental illnesses.
Methods: The process of data collection involved conducting a search on the Scopus website using specific keywords. Subsequently, the collected data is stored in the file formats of .bib and .csv. These files are then subjected to analysis using the biblioshiny and Vosviewer software tools. The research not only use quantitative analysis but also incorporates qualitative investigations.
Results: The trend of the most significant affiliations, authors, documents with the highest number of citations, relevant sources, cited nations, and annual scientific production was determined. This academic study employs many visualization techniques, including overlay visualization of the Scopus database, utilization of VOSviewer for database analysis, network visualization, density visualization, and thematic mapping.
Conclusions: The use of ultrasound as a neuromodulation therapy offers numerous opportunities and potential across various sub-topics, despite a limited literature corpus compared to other academic disciplines. The use of this discipline in human subjects is limited, requiring extensive clinical studies and cross-national collaboration for the advancement of therapeutic interventions.
Nanophthalmos with angle closure glaucoma, a challenging case
Authors: Elsa Gustianty  , Prahasta Andika , Rifada Raden Maula , Umbara Sonie 
Published: March 2024

Link of Video Abstract: https://youtu.be/eGhTbOkaaQI

Introduction: Nanophthalmos basically is a simple microphthalmos with clinical characteristics of short axial length (AL), shallow anterior chamber (AC), high lens to eye volume ratio, small cornea and thick sclera, associated with angle closure glaucoma. We report a case of nanophthalmos with angle closure glaucoma and cataract who underwent trabeculectomy and end up with malignant glaucoma. Pars plana vitrectomy (PPV) and phacoemulsification with posterior chamber intraocular lens (PC IOL) implantation was done to manage the case.
Case Description: A 41-year-old man came with blurred vision in the right eye with redness and headache for 8 weeks. Intraocular pressure (IOP) was 46 mmHg, visual acuity was counting fingers at 2 m with nystagmus. Slit lamp examination revealed short axial length (AL), shallow anterior chamber (AC), small corneal diameter and high lens to eye volume. Trabeculectomy with 5FU was done with complication of malignant glaucoma. After PPV combined with phacoemulsification and PC IOL implantation, IOP was 14 mmHg, visual acuity 0.125 with deep AC.
Conclusion: Surgical intervention in nanophthalmos with angle closure glaucoma must be managed with good preparation. Malignant glaucoma in this case can be managed with pars plana vitrectomy and phacoemulsification without scleral procedure.
The association between C-reactive protein (CRP)/Albumin Ratio (CAR) and the outcomes of patients with Ludwig's Angina
Authors: Purnama I Made Candra , Susilo Dwi Hari , Wibowo Maryono Dwi 
Published: March 2024

Link of Video Abstract: https://youtu.be/bd2v_SEY08Q

Background: A severe form of widespread cellulitis that affects the submandibular and submental regions is known as Ludwig's angina. The C-reactive protein/Albumin Ratio (CAR) was utilized to evaluate the prognosis of several different disorders. This research aims to evaluate the correlation between CAR and mortality as well as the outcome of patients with Ludwig's Angina. Additionally, it seeks to determine the optimal CAR ratio threshold for predicting mortality in Ludwig's Angina patients.
Methods: This study presents a retrospective cohort analysis of patients diagnosed with Ludwig's Angina aged over 20 years and underwent operative treatment at RSUD Dr. Soetomo Surabaya between January 2018 and April 2023. Data were analyzed using SPSS version 23.0 for Windows.
Results: 121 patients diagnosed with Ludwig's Angina were recruited for the study. In this study, most research subjects (65.4%) were male. The percentage of cases classified as mild, moderate, or severe was 5.4%, 58.5%, and 36.2%, respectively. The calculated cutoff value for CAR was determined to be 8.87. The model's sensitivity was 66%, indicating its ability to identify positive cases correctly. Similarly, the model's specificity was determined to be 66.3%, demonstrating its ability to identify negative cases correctly. The p-values for the relationship between CAR and patient outcome, severity, and length of stay (LOS) were found to be 0.001, 0.028, and 0.014 in each case.
Conclusion: The C-reactive protein/Albumin (CAR) ratio, which serves as an inflammatory marker, can be utilized to evaluate the mortality rate associated with Ludwig's Angina. This tool can stratify patients diagnosed with Ludwig's Angina.
Relationship of HER2 with age, gender, location of the tumor, and tumor budding in colorectal adenocarcinoma at H. Adam Malik General Hospital, Medan, Indonesia
Authors: Muhar Adi Muradi , Laksmi Lidya Imelda , Lubis Nova Sabrina 
Published: March 2024

Link of Video Abstract: https://youtu.be/_B_bL8gi7hU

Background: Colorectal carcinoma is one of the most common malignancies and is one of the leading causes of cancer-related death worldwide. The incidence of colorectal carcinoma in Indonesia is reported to be 12.8 per 100,000 adult population, accounting for 9.5% of all cancer-related deaths. Assessment of Human Epidermal Growth Factor Receptor 2 (HER2) expression is used to help predict tumor behavior and the effect of anti-HER2 receptor therapy. This study aims to analyze the relationship between HER2 immunohistochemical expression with age, gender, tumor location, and tumor budding in this malignancy.
Methods: This study is a cross sectional analytic study of 45 samples diagnosed with colorectal carcinoma at H. Adam Malik General Hospital Medan. Tumor budding was assessed for tumor invasiveness based on the International Tumor Budding Consensus Conference (ITBCC) 2016 in a field area of ​​0.785 mm2 with a 20x objective lens using a three-level scoring system, which was categorized into low budding (0-4 buds), intermediate budding (5-9 buds), and high budding (≥10 buds). Staining was performed using immunohistochemistry of the monoclonal anti-human HER2 anti-human DBS manufacturer, which would appear positive on the tumor cell membrane at a dilution of 1:100. HER2 expression was assessed using the HERACLES criteria. The results are presented as a score of 0, 1+, 2+, 3+, then categorized into negative (score 0-2+) and positive (score 3+). Data were analyzed using SPSS version 25.0 for Windows.
Results: There was no significant relationship between HER2 and clinicopathological parameters such as age (p=0.755), gender (p>0.05) and tumor location (p>0.05). However, there was a significant relationship between HER2 and tumor budding histopathological parameters with a value of p=0.011 in a positive direction (the greater the number of budding, the more positive HER2 expression, and vice versa).
Conclusion: HER2 is not significantly related to age, gender and tumor location. However, it is significantly associated with tumor budding. HER2 plays a role in the proliferation and differentiation of colorectal carcinoma tumor cells.
Analysis of vitamin D supplementation impact on carcinoembryonic antigen (CEA) levels in stage I-III colorectal cancer
Authors: Razi Khalikul , Putranto Agi Satria , Jeo Wifanto Sadityo , Tamba Riana Pauline , Herqutanto  
Published: March 2024

Link of Video Abstract: https://youtu.be/Bdcbzy1HDeM

Background: Colorectal cancer is a globally prevalent and highly lethal malignancy. While vitamin D supplementation may impact cancer risk, its precise effect remains unclear, especially in patients with early-stage III colorectal cancer. This research aimed to enhance our understanding of the potential advantages of vitamin D in colorectal cancer treatment in Indonesia.
Methods: This study is a randomized controlled clinical trial conducted from September 2022 to November 2023 at Cipto Mangunkusumo Hospital's Surgical Polyclinic (RSCM). Inclusion criteria encompass individuals aged 18 and above, diagnosed with stage I–III colorectal cancer, and without a history of surgical or chemotherapeutic colorectal cancer treatment. Exclusion criteria entail patients with a Karnofsky score below 60%, smokers, individuals with inflammatory bowel disease, and those diagnosed with malignancies other than colorectal carcinoma.
Results: The mean vitamin D level in all subjects before the intervention was 16.66 ± 6.23 ng/mL. The median pre-intervention CEA level stood at 4.70 (min-max 1.30–59.40). There was a notable change in CEA levels within the experimental group (median delta CEA: -0.20), and the response to vitamin D supplementation exhibited variations depending on the degree of cancer cell differentiation.
Conclusion: The outcomes of this study indicate that vitamin D supplementation can significantly reduce CEA levels in patients with stage I-III colorectal cancer who have not received prior medical treatment.
Comparing phacoemulsification and phacotrabeculectomy for managing primary angle-closure glaucoma with cataracts: a review
Authors: Universade Putri Anya , Komaratih Evelyn , Kencono W Citrawati Dyah 
Published: March 2024

Link of Video Abstract: https://youtu.be/mPotwhRZbsY

Cataracts and glaucoma are two leading causes of global blindness that are often found together, creating complex clinical challenges. Cataracts, which cause visual impairment by covering the eye's lens, and glaucoma, characterized by increased intraocular pressure and damage to the optic nerve, are mainly related to age and lens size. Mixed case management is becoming increasingly important in ophthalmic practice.
Choosing the right surgical technique is the key to overcoming both. This decision requires consideration of long-term effectiveness, benefits, and risk of complications. One technique that has emerged is phacotrabeculectomy, but the decision to choose this surgical technique is not easy because it requires considering various factors.
Further research and a better understanding of the management of this eye disease will be crucial in improving patients' quality of life and well-being. With the prevalence of cataracts and glaucoma continuing to increase as the population ages, an emphasis on effective and sustainable management strategies will significantly impact society's overall eye health. This review will compare phacoemulsification and phacotrabeculectomy for managing primary angle-closure glaucoma with cataracts.
Effectiveness of sclerotherapy injection in haemangioma of the head and neck region
Authors: Baihaqi Rizki , Wibowo Marjono Dwi 
Published: March 2024

Link of Video Abstract: https://youtu.be/6NXSL59eReA

Background: Hemangiomas are benign tumors that originate from blood vessels. Sclerotherapy effectively treats benign vascular lesions, especially small lesions located at sites with aesthetic impact. Polidocanol is the solution most commonly known to work by causing a local inflammatory reaction, thrombosis obliteration of the hemangiomatous space, and fibrosis of the endothelial space, leading to the lesion's regression. This study evaluated the effectiveness of polidocanol sclerotherapy injection therapy (Aethoxysklerol 3%) in patients with cavernous haemangioma at Dr. Soetomo general hospital.
Method: This study is a cross-sectional correlative analysis study, with research samples derived from medical records of patients with cavernous type haemangioma who were indicated to undergo sclerotherapy injection therapy (Aethoxysklerol 3%) at Dr. Soetomo general hospital in the period 2017-2023 who met the inclusion and exclusion criteria. The data obtained will be processed using SPSS software version 25.0 for Windows. Statistical tests were significant if the p-value was <0.05.
Results: There were 26 samples in this study, with the gender of patients mostly female (65.4%) and aged >20 years (38.5%). The most common location was buccal region hemangioma (34.2%). The results of the therapeutic response showed that 50% of the majority of patients not well responded, 34,2% showed no response, and only 15.4% responded well with a p-value = 0.000.
Conclusion: Injection sclerotherapy using polidocanol (Aethoxysklerol) in 3x administration sessions is a treatment method that has not been effective in treating hemangioma.
Evaluation of the CPIRO score on the outcomes of management actions for patients with hollow organ perforation at Dr. Soetomo General Hospital in the years 2019-2022
Authors: Zainuri Mohammad Maksum , Septarendra Denny , Wibowo Marjono Dwi 
Published: March 2024

Link of Video Abstract: https://youtu.be/k4WZuJF_ejc

Introduction: Generalized peritonitis is a surgical emergency caused by the perforation of hollow organs. In Indonesia, the incidence of peritonitis is approximately 179,000 cases. The CPIRO score is one of the scoring systems that can predict sepsis patients' prognosis and mortality. It is relatively straightforward to perform.
Methods: This study has an observational analytic design, a retrospective cohort from the medical record data of 94 patients with hollow organ perforation in the 2019-2022 treatment year at our health center, Dr. Soetomo Hospital, Surabaya. We performed a cross-sectional analysis and performance analysis by comparing the sensitivity, specificity, NPV, PPV and accuracy of each of the results of the CPIRO score in assessing mortality and determining the cutoff.
Results: We found that exploratory laparotomy dominates most procedures, as much as 73.4%. With the outcome of patients with hollow organ perforation, 52.1% died. The highest prevalence of CPIRO score is at score 4, with 35.1% of patients. It was also found that the optimalcCPIRO cut-off was 4 with sensitivity, specificity, PPV, NPV, and accuracy values of 77.6%, 75.6%, 77.6%, 75.6% and 76.6%, respectively, with p<0.001.
Conclusion: This concludes that the CPIRO score strongly correlates with the outcome and can be used to determine treatment choices for hollow organ perforation patients.
“Resignificaciones del VIH” historia de vida de un hombre gay después de un diagnostico
Authors: Bautista Eduardo Enrique Zetina , Vizcaino Gerardo Ivan Martinez 
Published: March 2024

Objetivos: Recupera las resignificaciones de “vivir con VIH” a través de la historia de un hombre gay de 38 con 7 años de diagnóstico.
Materiales y Métodos: Estudio fenomenológico a partir de la historia de vida de un hombre gay residente del Área Metropolitana de México, a partir de una entrevista semi estructurada, se recuperan las vivencias entorno al VIH. Teniendo como interrogante fenomenológica “¿Como ha sido la experiencia con el VIH?”.
Resultados: Su enfermedad más “significativa” es el VIH, sentir que “no debe ser una carga” es una visión de cuidador, con un auto demanda y autoexigencia que lo ha llevado a no hablar abiertamente su diagnóstico con su familia llevándolo a buscar otras redes de apoyo. Ver el VIH como un juicio que le “debería de dar” a personas que son “más promiscuas o tienen más parejas”; es una idea que se confronta con la vivencia personal, así como las formas de relacionarse en pareja y laboralmente. Envejecer, vivir con VIH y tener una pareja; son situaciones actuales que se relación con las vivencias anteriores. Suponiendo que por vivir con VIH el desgaste será mayor.
Conclusiones: La resignificación del VIH es un proceso dinámico que la persona experimenta a lo largo de su vida, dicho proceso estará mediado por contextos socio históricos e individuales. Combatir el estigma es un proceso colectivo y relacional entre los profesionales de salud y la población atendida.
Crack-filling effect of gel on time-dependent mechanical behavior of concrete damaged by alkali–silica reaction
Authors: Joo Hyo Eun , Takahashi Yuya 
Published: March 2024

AbstractThis study aims to investigate the crack-filling effect of gel generated by the alkali–silica reaction (ASR) on the mechanical behavior of concrete and propose an analytical model to predict the compression behavior of ASR-damaged concrete. To identify the mechanical contribution of the gel-filling cracks, the distribution of the chemical compositions and elastic moduli of the crack-filling gels were observed using SEM–EDS analysis and nano-indentation tests. The experimental results showed that the elastic modulus of the gel with a high-calcium composition ranged from 30 to 40 GPa, which is comparable to the elastic modulus of concrete. In addition, through literature reviews of the time-dependent compression behaviors of ASR-affected concrete, it was hypothesized that crack-filling gels can contribute to the recovery of ASR damage, and that the mechanical contribution of gels depends on the ASR crack patterns and changes with time. Based on these assumptions, the resistance of the gels filling the cracks in the compression, shear, and recontact behaviors of ASR-damaged concrete was reflected in the proposed model, in which the gel resistance increased with time and became larger as the ratio of microcracks to total cracks increased. The proposed model was verified through a comprehensive comparison of analysis and test results of compression behavior of ASR-damaged specimens, and it appeared that the change in mechanical properties of concrete according to the degree of damage (ASR expansion) and time was well simulated by the proposed model.