bluuebunny/crossref_metadata_2025_split huggingface dataset:
Immuno-antioxidative reno-modulatory effectiveness of Echinacea purpurea extract against bifenthrin-induced renal poisoning
Authors: Abdel-Wahhab Khaled G. , Elqattan Ghada M. , EL-Sahra Doaa G. , Hassan Laila K. , Sayed Rehab S. , Mannaa Fathia A. 
Published: March 2024

AbstractThis study was conducted to evaluate the ameliorative, anti-inflammatory, antioxidant, and chemical detoxifying activities of Echinacea purpurea ethanolic extract (EEE) against bifenthrin-induced renal injury. Adult male albino rats (160–200 g) were divided into four groups (10 rats each) and orally treated for 30 days as follows: (1) normal control; (2) healthy animals were treated with EEE (465 mg/kg/day) dissolved in water; (3) healthy animals were given bifenthrin (7 mg/kg/day) dissolved in olive oil; (4) animals were orally administered with EEE 1-h prior bifenthrin intoxication. The obtained results revealed that administration of the animals with bifenthrin caused significant elevations of serum values of urea, creatinine, ALAT and ASAT, as well as renal inflammatory (IL-1β, TNF-α & IFN-γ), apoptotic (Caspase-3) and oxidative stress (MDA and NO) markers coupled with a marked drop in the values of renal antioxidant markers (GSH, GPx, and SOD) in compare to those of normal control. Administration of EEE prior to bifenthrin resulted in a considerable amelioration of the mentioned deteriorated parameters near to that of control; moreover, the extract markedly improved the histological architecture of the kidney. In conclusion, Echinacea purpurea ethanolic extract has promising ameliorative, antioxidant, anti-inflammatory, renoprotective, and detoxifying efficiencies against bifenthrin-induced renal injury.
Comprehensive antifungal investigation of green synthesized silver nanoformulation against four agriculturally significant fungi and its cytotoxic applications
Authors: Singh Jyoti , Kumar Ankit , Nayal Amit Singh , Vikal Sagar , Shukla Gyanika , Singh Amardeep , Singh Anupma , Goswami Sakshi , Kumar Ashwani , Gautam Yogendra K. , Verma Yeshvandra , Gaurav Shailendra Singh , Pratap Dharmendra 
Published: March 2024

AbstractThe present study reports the green synthesis of silver nanoparticles (AgNPs) in powder form using the leaf extract of Azadirachta indica. The synthesis of AgNPs was confirmed by UV–vis spectroscopy, FTIR, XRD, FESEM, and EDX. The synthesized AgNPs were in a powdered state and dispersed completely in 5% polyethylene glycol (PEG) and demonstrated prolonged shelf life and enhanced bioavailability over a year without any aggregation. The resulting silver nanoformulation demonstrated complete inhibition against Sclerotinia sclerotiorum and Colletotrichum falcatum and 68% to 80% inhibition against Colletotrichum gloeosporioides and Rhizoctonia solani respectively, at 2000 ppm. The EC50 values determined through a statistical analysis were 66.42, 157.7, 19.06, and 33.30 ppm for S. sclerotiorum, C. falcatum, C. gloeosporioides, and R. solani respectively. The silver nanoformulation also established significant cytotoxicity, with a 74.96% inhibition rate against the human glioblastoma cell line U87MG at 250 ppm. The IC50 value for the cancerous cell lines was determined to be 56.87 ppm through statistical analysis. The proposed silver nanoformulation may be used as a next-generation fungicide in crop improvement and may also find application in anticancer investigations. To the best of our knowledge, this is also the first report of silver nanoformulation demonstrating complete inhibition against the economically significant phytopathogen C. falcatum.
Modular intercalary prosthetic reconstruction for malignant and metastatic tumours of the proximal femur
Authors: Liu Lu , Deng Xiao-qiang , Zhao Yong-jie , Ma Rong-xing , Yang Li , Song Kun-xiu , Zhang Jing-yu , Hu Yong-cheng 
Published: March 2024

AbstractTo illustrate the surgical technique and explore clinical outcomes of the reconstruction for the malignant and metastatic bone tumour of proximal femur with metallic modular intercalary prosthesis. Sixteen patients who underwent modular intercalary prosthetic reconstruction after tumour resection were included from April 2012 and October 2020. Prosthesis and screws parameters, resected bone length and residual bone length, clinical outcomes and survivorship were analyzed. All patients were followed up for an average of 19 months (range 1–74). In our series, 12 patients died of the progression of the primary disease at the final follow-up. The cumulative survivorship since the treatment of proximal femoral metastasis was 78.6% (11 patients) at 6 months and 38.5% (5 patients) at 1 year. The mean MSTS score was 22.25 ± 4.55 among all patients. There were no cases of loosening or breakage of the prostheses, plates or screws, despite the various measurements of prostheses and residual bones. Modular intercalary prosthetic reconstruction was an effective method for malignant tumour of the proximal femur, including the advantages of providing early pain relief, quickly restoring postoperative function, required a short operation time, and preserving the adjacent joints.
P. aeruginosa CtpA protease adopts a novel activation mechanism to initiate the proteolytic process
Authors: Hsu Hao-Chi , Wang Michelle , Kovach Amanda , Darwin Andrew J , Li Huilin 
Published: March 2024

AbstractDuring bacterial cell growth, hydrolases cleave peptide cross-links between strands of the peptidoglycan sacculus to allow new strand insertion. The Pseudomonas aeruginosa carboxyl-terminal processing protease (CTP) CtpA regulates some of these hydrolases by degrading them. CtpA assembles as an inactive hexamer composed of a trimer-of-dimers, but its lipoprotein binding partner LbcA activates CtpA by an unknown mechanism. Here, we report the cryo-EM structures of the CtpA–LbcA complex. LbcA has an N-terminal adaptor domain that binds to CtpA, and a C-terminal superhelical tetratricopeptide repeat domain. One LbcA molecule attaches to each of the three vertices of a CtpA hexamer. LbcA triggers relocation of the CtpA PDZ domain, remodeling of the substrate binding pocket, and realignment of the catalytic residues. Surprisingly, only one CtpA molecule in a CtpA dimer is activated upon LbcA binding. Also, a long loop from one CtpA dimer inserts into a neighboring dimer to facilitate the proteolytic activity. This work has revealed an activation mechanism for a bacterial CTP that is strikingly different from other CTPs that have been characterized structurally.
Lipidomics reveals new lipid-based lung adenocarcinoma early diagnosis model
Authors: Sun Ting , Chen Junge , Yang Fan , Zhang Gang , Chen Jiahao , Wang Xun , Zhang Jing 
Published: March 2024

AbstractLung adenocarcinoma (LUAD) continues to pose a significant mortality risk with a lack of dependable biomarkers for early noninvasive cancer detection. Here, we find that aberrant lipid metabolism is significantly enriched in lung cancer cells. Further, we identified four signature lipids highly associated with LUAD and developed a lipid signature-based scoring model (LSRscore). Evaluation of LSRscore in a discovery cohort reveals a robust predictive capability for LUAD (AUC: 0.972), a result further validated in an independent cohort (AUC: 0.92). We highlight one lipid signature biomarker, PE(18:0/18:1), consistently exhibiting altered levels both in cancer tissue and in plasma of LUAD patients, demonstrating significant predictive power for early-stage LUAD. Transcriptome analysis reveals an association between increased PE(18:0/18:1) levels and dysregulated glycerophospholipid metabolism, which consistently displays strong prognostic value across two LUAD cohorts. The combined utility of LSRscore and PE(18:0/18:1) holds promise for early-stage diagnosis and prognosis of LUAD.
Design and construction of a refrigerator-cooled adiabatic calorimeter for heat capacity measurement in liquid helium temperature region
Authors: Luo Ji-Peng , Yin Nan , Lu Jia-Bao , Tan Zhi-Cheng , Shi Quan 
Published: March 2024

Heat capacity is a fundamental thermodynamic property of a substance. Although heat capacity values and related thermodynamic functions are available for many materials, low-temperature heat capacity measurements, especially for novel materials, can still provide valuable insights for research in physics, chemistry, thermodynamics, and other fields. Reliable low-temperature heat capacity data are typically measured using classical adiabatic calorimeters, which use liquid helium as the refrigerant to provide a cryogenic environment for heat capacity measurements. However, liquid helium is not only expensive but also not easy to obtain, which greatly limits the application of adiabatic calorimetry. In this work, an accurate adiabatic calorimeter equipped with a Gifford–MacMahon refrigerator was designed and constructed for measuring the heat capacity of condensed matter in the temperature range from 4 to 100 K. The Gifford–MacMahon refrigerator was utilized to provide a stable liquid helium-free cryogenic environment. A simple mechanical thermal switch assembly was designed to facilitate switching between the refrigeration mode and the adiabatic measurement mode of the calorimeter. Based on the measurement results of standard reference materials, the optimized repeatability and accuracy of heat capacity measurements were determined to be within 0.8% and 1.5%, respectively. The heat capacity of α-Fe2O3 nanoparticles was also investigated with this device. Furthermore, this adiabatic calorimeter only requires electricity to operate in the liquid helium temperature range, which may significantly advance the research on low-temperature heat capacity based on adiabatic calorimetry.
Decision-making in the translation of proper-name allusions
Authors: Ren Haimeng 
Published: March 2024

Abstract
As an intertextual and culture-specific expression, allusion activates two texts simultaneously, embedding them
with intended meaning from the source culture but not necessarily in the target culture. In the context of L1 translation being
the majority, allusions can be puzzles that cause “cultural bumps” for translators unfamiliar with the source culture and
language. It is a concern whether translators can accurately and appropriately handle allusions, e.g., proper-name and key-phrase
allusions. This paper focused on the novice translator’s utilization of translation strategies in both directions of translation
to find out how they deal with proper-name allusions and what might influence their choice of strategies. The results suggest that
the translators have distinct preferences for the strategies used to translate proper-name allusions in both directions of
translation. The findings further identified potential factors that motivated the novice translators’ decision-making process.
They revealed their translation competence and awareness that may influence the decision-making of translators handling
proper-name allusions.
The interpretation of reflexive pronouns in VP-ellipsis by L2 English learners with different proficiency
levels
Authors: Gallardo-del-Puerto Francisco , Gandón-Chapela Evelyn 
Published: March 2024

Abstract
English reflexive anaphora in cases of VP-ellipsis may allow for strict and sloppy readings. A few L2 studies
(Epoge, 2012; Park, 2016; Ying, 2005) have focused on determining the role that L2 proficiency may exert on
learners’ choices in bare, referential, and non-referential contexts. This paper provides data from 104 Spanish learners of
English (A2, B1, and B2 levels) and 32 native speakers of English. Results showed that participants tended to interpret reflexives
sloppily in bare and non-referential contexts, whereas strict readings prevailed in referential ones. There existed significant
differences in the interpretation of learners versus native speakers, whilst the differences among the three learner groups were
not so marked. However, the least proficient group differed most from native speakers. Findings partially confirm previous
research and discrepancies may be tentatively ascribed to extraneous variables (e.g., the learners’ L1, the range of the
proficiency levels, or the characteristics of the control groups).
Task complexity and task type
Authors: Entezari Mahnaz , Tadayonifar Mojtaba 
Published: March 2024

Abstract
In Task-Based Language Teaching (TBLT), there is clearly a need
for a balanced and flexible view of L1 use. Considering this, a matter of
concern in TBLT is that learners might overuse their first language (L1) while
performing complex tasks. To test this speculation, the present study
investigated the effects of manipulating task complexity along
resource-directing variables (+/− reasoning demands) of the Cognition Hypothesis
on L1 use and its functions. Further it aimed to test the impacts of task type
on L1 use and its functions. To do so, the interaction of 24 intermediate EFL
learners while completing two different task types with two levels of task
complexity was analyzed. The analysis of L1 words and turns indicated that both
task complexity and task type affected L1 use significantly. The results further
indicated that L1 was employed for a variety of purposes which were mainly
affected by task complexity.
Coherent perfect absorption of light by undoped graphene monolayer
Authors: Ukhtary M Shoufie 
Published: March 2024

Abstract
We show theoretically that coherent perfect absorption (CPA) of light is possible by a graphene monolayer without doping. To achieve the CPA, undoped graphene is embedded inside a multilayer structure called mirror structure, which increases the effective impedance of the surrounding medium. The increased effective impedance allows the destructive interference of light outside the structure that induces an increased Joule heat generating perfect absorption of light by graphene. We find that the CPA is possible for any wavelength as long as the thickness of each layer of the structure is a quarter of the corresponding wavelength. By changing the incident wavelength, but keeping the thickness of each layer, we show that the optical absorption is sensitive to the change of the incident wavelength. Therefore, we can design a photo detector for a specific wavelength.
Plasma characteristics and de-icing of three-electrode double-sided pulsed surface dielectric barrier discharge
Authors: Wang Fangyuan , Peng Bangfa , Jiang Nan , Li Jie 
Published: March 2024

Abstract
Ice accumulation on aircraft can lead to aerodynamic performance degradation and even trigger security incidents. However, traditional surface dielectric barrier discharge (SDBD) reactors cannot work while covered by glaze ice. In the present work, a novel three-electrode double-sided SDBD is proposed and employed for glaze ice deicing. Compared with traditional SDBD reactor, three-electrode double-sided SDBD introduces an additional discharge area and grounding electrode. On one hand, the heat generated in the additional discharge area can melt the glaze ice covered on the high-voltage electrode, providing a discharge gap for the subsequent discharge. On the other hand, the introduction of the additional grounding electrode can also dramatically enhance the upper discharge and thermal effect. As a result, compared with the three-electrode single-sided SDBD and two-electrode double-sided SDBD, the three-electrode double-sided SDBD has the highest deposited energy, maximal temperature, and deicing rate. To further optimize the structural design, the effect of air gap length below the dielectric on three-electrode double-sided SDBD is investigated. And it is found that the best deicing performance can be obtained at the air gap length of 1 mm.
Resonant-cavity-enhanced 4H-SiC thin film MSM UV photodetectors on SiO2/Si substrates
Authors: He Fuxiu , Jiao Jinlong , Li Zihao , Yao Liqiang , Ji Ruoyun , Wang Dan , Hu Yueping , Huang Wei , Li Cheng , Lin Guangyang , Wang Fuming , Zhang Feng , Chen Songyan 
Published: March 2024

Abstract
Heterogeneous integration of 4H-SiC film with Si substrate can produce ultraviolet (UV) photodetectors (PD) with higher performance and easier integration with silicon CMOS circuits than homogenous epitaxy of 4H-SiC on SiC substrates. In this study, 1.2 µm thick high-quality single crystalline 4H-SiC thin films were successfully bonded with SiO2/Si (100) substrates using the Smart-Cut technique, achieving bubble-free bonding interfaces and 6.03 MPa bonding strength. UV PDs of metal–semiconductor–metal type with a resonant cavity structure were fabricated for the first time using the heterogenous film sample. The device exhibits a low dark current of 1.6 × 10−13 A in reverse bias of 20 V and a maximum specific detectivity of about 5.2 × 1012 Jones at 280 nm, which is significant for a device with a resonance-enhanced structure. These results demonstrate a promising approach for the fabrication of 4H-SiC devices with silicon CMOS circuits.
Size-dependent bistability of magnetic states in soft magnetic cap arrays
Authors: Sam Shan Abraham , Seyd Johannes , Ullrich Aladin , Jung Florian , Groß Felix , Krupiński Michal , Albrecht Manfred , Thomas Senoy 
Published: March 2024

Abstract
We have investigated the size dependent energy barrier regarding the transition between magnetic vortex and collinear states in dense arrays of magnetic cap structures hosting magnetic vortices. The cap structures were formed by the deposition of soft magnetic thin films on top of large arrays of densely packed polystyrene spheres. The energy barrier associated with the magnetic field assisted switching from a collinear magnetic state to a non-uniform vortex state (or vice versa) was tuned by tailoring the diameter and thickness of the soft magnetic caps. At a sufficient temperature, known as the bifurcation temperature, the thermal energy overcomes this energy barrier and magnetic bistability with a hysteresis-free switching occurs between the two magnetic states. In magnetic caps with a fixed thickness, the bifurcation temperature decreases with increasing cap diameter. On the other hand, for a fixed diameter, the bifurcation temperature increases with an increase in film thickness of the cap structure. This study demonstrates that the bifurcation temperature can be easily tailored by changing the magnetostatic energy contribution which in turn affects the energy barrier and thus the magnetic bistability.
Study of synchronous RF pulsing in dual frequency capacitively coupled plasma
Authors: Verma Abhishek , Rauf Shahid , Bera Kallol , Sydorenko D , Khrabrov A , Kaganovich Igor 
Published: March 2024

Abstract
Low-pressure multi-frequency capacitively coupled plasmas (CCPs) are used for numerous etch and deposition applications in the semiconductor industry. Pulsing of the radio-frequency (RF) sources enables control of neutral and charged species in the plasma on a millisecond timescale. The synchronous (i.e. simultaneous, in-phase) pulsing of both power sources in a dual frequency CCP is examined in this article. Due to the low gas pressure, modeling has been done using the electrostatic particle-in-cell/Monte Carlo collision method. The objective of this work is to investigate the sensitivity of the plasma properties to small changes in timing during synchronous pulsing of the two RF sources. It is demonstrated that small deviations in the on and off times of the two RF sources can lead to major changes in the plasma characteristics. This high sensitivity is of concern for process repeatability but can be utilized to enable better control of the dynamics of plasma-surface interaction. In the simulations, the pulsing parameters (on and off times and ramp rates) are varied and the temporal evolution of plasma characteristics such as electron density (ne
), species current at the electrode, and electron temperature are examined. It is demonstrated that if the low-frequency (LF) source is turned off a few μs before (or after) the high-frequency source, ne
during the off-state is significantly higher (or lower) due to the frequency coupling effect. Similarly, turning on the LF source with a small delay results in a sharp increase in the plasma density when the RF sources are turned on.
Chaotic image encryption algorithm based on dynamic Hachimoji DNA coding and computing
Authors: Wu Ximei , Zhong Chen , Long Bofeng , Liu Tongzhe , He Chenchen , Wang Lujie 
Published: March 2024

Abstract
With the increasing awareness of privacy protection, people pay more and more attention to strengthening the security of image data transmitted over the network. Therefore, this paper designs a chaotic image encrypting algorithm based on dynamic Hachimoji DNA coding and computing to protect images. The Hachimoji DNA coding method provides richer coding rules to dynamically encode images than the traditional DNA coding method, improving the complexity and security of the encryption algorithm. First, the original image is rearranged and encoded with the dynamic Hachimoji DNA coding method according to the sorting and encoding controller sequence generated by a six-dimensional hyperchaotic system. Second, various DNA operations are performed on the encoded image. Among these operations, we not only use the common operations but also propose a new DNA operation called bitwise inversion. Finally, the DNA image is decoded using the dynamic decoding method to obtain the encrypted image. Experiments demonstrated that the image encryption algorithm has a good security effect and can effectively resist common attacks.
Highly birefringent photonic crystal fibers with near-zero flattened dispersion for polarization-maintaining terahertz transmission
Authors: Yang Huailin , Yang Jian , Xu Qibo , Shen Zhengyu , Yang Hua 
Published: March 2024

Abstract
In this work, we present a novel hexagonal lattice porous-core photonic crystal fiber (PCF) exhibiting high birefringence, low loss, and near-zero flattened dispersion in the terahertz regime. The core design incorporates asymmetric rectangular and triangular air holes to achieve enhanced birefringence performance. The background material, TOPAS, is carefully selected to minimize dispersion and transmission losses. Furthermore, by employing the finite element method, the guiding properties of the proposed PCF are comprehensively investigated. Our simulation results reveal a near-zero flattened dispersion value of

±
0
.2ps
⋅

THz

−
1

⋅

cm

−
1

within a broad frequency range of

0.8
−
1.6

THz
,

accompanied by an impressive birefringence value of

0.072
.

Additionally, the PCF demonstrates outstanding characteristics in terms of confinement loss, effective material loss, effective mode area, core power fraction, and bending loss. Considering its exceptional attributes, the proposed PCF holds significant promise for polarization-maintaining applications and terahertz communication systems.