bluuebunny/crossref_metadata_2025_split huggingface dataset:
“Burst and slow complexes” in nonconvulsive epileptic status
Authors: Ikeda Akio , Matsui Masaru , Hase Yoshiki , Hitomi Takehumi , Takahashi Yukitoshi , Shibasaki Hiroshi , Shimohama Shun 
Published: March 2024

ABSTRACT
Generalized 1Hz, burst‐and‐slow‐wave complexes were observed in a comatosed patient with acute disseminated encephalomyelitis (ADEM) when she showed extremely intractable, generalized convulsions and fragmented myoclonus in the whole body. Two types of short‐latency SEPs were obtained separately during the burst and slow phase of the EEG (SEP‐burst and SEP‐slow, respectively), which showed a two fold greater amplitude of N20 in the former than in the latter. This suggests enhanced responsiveness to the peripheral stimuli during the burst phase as compared with the slow phase. CSF and serum were positive for autoantibodies to NMDA receptors. The “burst and slow complexes” reported here are considered to be an atypical EEG pattern of a generalized epileptic phenomenon.
Lingual epilepsia partialis continua in Rasmussen's encephalitis
Authors: Nayak Dinesh , Abraham Mathew , Kesavadas Chandrasekharan , Radhakrishnan Kurupath 
Published: March 2024

ABSTRACT
We report an adult male who presented with disabling dysarthria due to epilepsia partialis continua (EPC) of the left half of the tongue. The clinical, brain magnetic resonance imaging and electroencephalographic features were consistent with Rasmussen's encephalitis, although, despite having had the disease for over 15 years, he did not exhibit any hemiparesis. The accompanying video illustrates the lingual EPC and its total resolution following a right frontal opercular focal cortical resection.

[Published with video sequences]
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Senile myoclonic epilepsy in Down syndrome: a video and EEG presentation of two cases
Authors: De Simone Roberto , Daquin Géraldine , Genton Pierre 
Published: March 2024

ABSTRACT
Myoclonic epilepsy is being increasingly recognized as a late‐onset complication in middle‐aged or elderly patients with Down syndrome, in association with cognitive decline. We show video and EEG recordings of two patients, both aged 56 years, diagnosed with this condition. At onset, myoclonic epilepsy in elderly DS patients may resemble, in its clinical expression, the classical juvenile myoclonic epilepsy with the characteristic occurrence of jerks on awakening. It is clearly associated with an Alzheimer‐type dementia, and may also occur in non‐DS patients with Alzheimer's disease: hence the possible denomination of “senile myoclonic epilepsy”.

[Published with video sequences]
Epilepsy and multiple sclerosis
Authors: Lebrun Christine 
Published: March 2024

ABSTRACT
Epilepsy is three to six times more frequent in multiple sclerosis than in the general adult population. The probable anatomic basis for the seizures is areas of inflammation and demyelination in the cortex and juxtacortical white matter. Partial epilepsies with focal seizures often with atypical symptoms and with or without secondary generalisation are the usual pattern. Seizures can be observed as the first symptom of multiple sclerosis, or during relapses, with a direct correlation between paroxysmal phenomena and plaques demonstrated by brain MRI. Infrequently, it can start during the progressive phase, without active inflammation, generally associated with brain atrophy and high lesion load. Generally, the prognosis of epilepsy in multiple sclerosis patients is estimated to be good, without special recommendations or consensus for the choice of anti‐epileptic drug. Non‐epileptic paroxysmal symptoms may be confused with epileptic seizures. It usually responds to many different antiepileptic drugs.
Epilepsy and alcohol
Authors: Bartolomei Fabrice 
Published: March 2024

ABSTRACT
While the links between alcoholism and epilepsy are well demonstrated, the classification of alcohol related seizures is still controversial. The best recognized seizures are the “alcohol withdrawal seizures” (AWS). However, experimental and clinical data strongly suggest that withdrawal is not the only mechanism by which the chronic absorption of alcohol may act. Specific epileptogenesis may underlie seizures unrelated to withdrawal (SUW). Epileptogenesis in this context involves several mechanisms including alterations of excitation/inhibition systems and a kindling‐like effect. A classification scheme was proposed in which patients presenting with seizures unrelated to any cause other than alcohol are classified in several successive stages of “alcoholic epilepsy”, the first being characterized by AWS, the second by SUW and the last by persistent chronic seizures.
Anticonvulsant effects of N
6
‐cyclohexyladenosine microinjected into the CA1 region of the hippocampus on entorhinal cortex‐kindled seizures in rats
Authors: Heidarianpour Ali , Sadeghian Efat , Mirnajafi‐Zadeh Javad , Fathollahi Yaghoub , Mohammad‐Zadeh Mohammad 
Published: March 2024

ABSTRACT

In this study, the role of adenosine A1 receptors of the hippocampal CA1 region in entorhinal cortex‐kindled seizures was investigated in rats. Animals were kindled by daily electrical stimulation of the entorhinal cortex. In fully kindled rats, N
6
‐cyclohexyladenosine (CHA; a selective A1 receptor agonist) and 1, 3‐dimethyl‐8‐cyclopenthylxanthine (CPT; a selective A1 receptor antagonist) were microinfused bilaterally into the hippocampal CA1 region. Rats were stimulated and seizure parameters were measured. Results obtained showed that CHA (10 and 50 μ moles) decreased the afterdischarge duration (ADD) in the hippocampal CA1 region and entorhinal cortex, stage 5 seizure duration (S5D) and seizure duration (SD) only at the dose of 50 μ moles, and significantly increased the latency to stage 4 (S4L). Intrahippocampal CPT increased ADD and S5D, and significantly reduced the latency to stage 4 (S4L) at the dose of 10 lmoles. Pretreatment of rats with CPT (5 μ moles) before CHA (50 μ moles), significantly reduced the effect of CHA on seizure parameters. The results suggest that the CA1 region of the hippocampus plays an important role in spreading seizure spikes from the entorhinal cortex to other brain regions and activation of adenosine A1 receptors in this region participates in the anticonvulsant effects of adenosine agonists.
Sharnie
Authors: LONG RACHEL 
Published: March 2024

Rachel Long’s debut collection, My Darling from the Lions (Picador 2020 / Tin House 2021) was shortlisted for the Forward Prize for Best First Collection, The Costa Book Award, The Rathbones Folio Prize, and The Sunday Times Young Writer of the Year Award. The US edition featured in the New York Times Book Review, and was named one of the 100 must-read books of 2021 by TIME. An earlier version of this poem was published in The Poetry Review, Vol. 112, No. 3, Autumn 2022
УПРАВЛІННЯ ПЕРСОНАЛОМ ПІДПРИЄМСТВ ЗАЛІЗНИЧНОГО ТРАНСПОРТУ: ОПЛАТА ТА МОТИВАЦІЯ ПРАЦІ
Authors: Кірдіна О. Г. , Лубєнцова Л. В. 
Published: March 2024

Досліджено особливості оплати праці та мотивації персоналу підприємств залізничного транспорту. Встановлено, що системі оплати праці та мотивації працівників підприємств галузі притаманна низка недоліків, викликаних ігноруванням потреб та цінностей персоналу і реалізацією протягом багатьох років неефективної кадрової політики. Вказано на ускладнення, викликані дистанційним форматом роботи працівників підприємств залізничного транспорту, що призвели до загострення кадрових проблем. Сформовано підхід до формування системи оплати праці та мотивації персоналу підприємств залізничного транспорту, що розкриває напрями та інструменти її удосконалення. Розкрито традиційні та прогресивні інструменти мотивації працівників підприємств залізничного транспорту. Доведено, що використання запропонованого підходу дозволить реалізувати потенціал кожного співробітника, створити умови для генерації та реалізації інноваційних ідей і професійного особистісного зростання персоналу.
ФОРМУВАННЯ СИСТЕМИ УПРАВЛІННЯ ЗНАННЯМИ НА ПІДПРИЄМСТВАХ ЗАЛІЗНИЧНОГО ТРАНСПОРТУ В КОНТЕКСТІ ЗАБЕЗПЕЧЕННЯ ІННОВАЦІЙНОГО РОЗВИТКУ
Authors: Токмакова І. В. , Іванова А. Д. , Бочков О. В. 
Published: March 2024

Досліджується вплив управління знаннями на забезпечення інноваційного розвитку підприємств залізничного транспорту. Знання і систему управління ними визнано внутрішнім чинником активізації інноваційної діяльності на підприємствах залізничної галузі. Встановлено компоненти системи знань підприємств, до яких відносять інтелектуальну власність, внутрішню документацію, різні екзогенні джерела інформації і знань, використовуваний в діяльності підприємства пул інформаційно-комунікаційних технологій, компетенції працівників (їх явні та неявні знання, кваліфікація, професійний досвід, майстерність тощо), культуру знань підприємства, інтеракції між співробітниками. Проаналізовано трактування вченими поняття «управління знаннями». Систематизовано визначення терміну «управління знаннями» за запропонованими підходами (процесним, управлінських технологій, з позицій стратегії, результативним). Зроблено висновок, що управління знаннями – це цілеспрямована та систематична управлінська діяльність щодо забезпечення ефективного використання знань на підприємстві. Вона включає розробку методик, процедур, стандартів, визначення джерел, створення інструментів для пошуку, отримання, поширення, оцінки, зберігання, трансферу та перетворення знань, необхідних елементів інтелектуального капіталу. З’ясовано принципи, якими слід керуватися при формуванні системи управління знаннями на підприємствах залізничного транспорту. Визначено ключові етапи управління знаннями, а саме створення, накопичення, передача, поширення, застосування знань і звільнення від застарілих знань відповідно до появи нових. Розкрито інформаційні технології, що сприяють підвищенню ефективності управління знаннями.
EFEITOS DO MANGANÊS NA MORFOLOGIA DA Lemna minor L. (Araceae)
Authors: Ferreira Samarah Christina Cantanhede , Silva Karine Sousa da , Farias Priscya Etielle Silva , Coutinho Arthur Baeta , Zanandrea Ilisandra 
Published: March 2024

O presente trabalho objetivou comparar as respostas fisiológicas da espécie Lemna minor L. frente ao aumento da concentração do metal manganês (Mn) em solução nutritiva, e se essas plantas são capazes de fitorremediar ambientes com altas concentrações deste metal pesado. As plantas foram coletadas em lagos artificiais, sem aparente contaminação por manganês, localizado no Viveiro Tracoá na região de São José de Ribamar - MA. O experimento foi realizado em placas de petri, onde foram adicionados 350 ml de solução nutritiva de Hoagland acrescida de doses crescentes de Mn (0; 0,2; 0,5 e 0,7mM)) na forma de MnCl₂, com 1 ⁄ 4 de força iônica. O experimento foi conduzido em delineamento inteiramente casualizado, com cinco repetições, sendo a unidade experimental constituída por 30 plantas. Foram avaliadas características morfológicas da espécie submetidas a concentrações crescentes de Mn. Os indivíduos de todos os tratamentos, exceto o tratamento controle, apresentaram sintomas visuais de toxidez, observando- se, cloroses, enrugamento e enrolamento da lâmina foliar e necroses. Apesar disso, não houve morte de nenhuma planta de L. minor, o que sugere que é uma espécie que possui capacidade para acumular este elemento sem grandes prejuízos para as plantas. Dessa maneira, conclui-se que a espécie L.minor, apresenta potencial para ser utilizada na fitorremediação e oferece um novo recurso para explorar e descobrir os mecanismos de acúmulo do Mn nas plantas, além de auxiliar na limpeza de águas contaminadas.
Temporal-Spatial Variations Analysis of Surface Temperature in Kalimantan Region for The Period of 2010 - 2020
Authors: Fitrianingtyas Rahmawati , Palupi Indriati Retno 
Published: March 2024

Surface temperature information is important to study because it affects other climate parameters and has an impact on various sectors. This study aims to analyze the temporal and spatial variations of maximum surface temperature on Kalimantan Region during the period 2010 to 2020. The data used is Surface Maximum Temperature (SMT) in the form of a 0.5o x 0.5o grid from the Climate Prediction Center (CPC) NOAA PCL. The results of the temporal analysis showed that the highest monthly SMT values occurred in May (32.00o C) and September (31.75o C). While the lowest monthly SMT values were found in January (30.88o C) and July (31.40o C). The results of the annual SMT trend analysis show that the surface temperature in the Kalimantan Region has increased at an average rate of 0.03°C per year. This value is higher than the increase in global surface temperature (~0.02°C per year). Based on the results of spatial analysis, it was known that the distribution of SMT on Kalimantan Region tends to be stable in the range of 25o C to 35o C throughout the year. Spatial analysis of SMT in 2011 showed that low values (25o - 31o C) dominated South Kalimantan Province , while high values (33°C - 35°C) dominated West Kalimantan Province. The results of the 2019 SMT spatial analysis revealed a similar pattern to 2011. However, there was a significant increase in temperature compared to 2011, especially in the high SMT values observed in West Kalimantan and East Kalimantan Provinces.
27th Bilateral Symposium Poznan-Halle Rare diseases in clinical practice
Authors: Wąsiel Bartłomiej 
Published: March 2024

As part of long-term bilateral cooperation with Martin Luther University in Halle, the 27th Bilateral Symposium Poznań-Halle "Rare diseases in clinical practice" was held on December 16. The participants of the symposium included research workers of both partner universities. On this occasion, talks were held to set up research groups that will carry out joint activities in the field of science and research and the first Poznań-Halle groups were tentatively established. Presentation of prizes for the best oral and poster presentations is a long-standing tradition of the symposium. This award is named after two Professors: Prof. Zeige and Prof. Hasik, who initiated cooperation between our Universities over 30 years ago. In the current edition of the symposium the first prize, two second prizes and two third prizes were given. To add, two representatives of our university were honored. The first prize went to Krzysztof Piersiała, a 6th year student of the First Medical Faculty I and the deputy chairman of the Student Scientific Club at the Clinic of Otolaryngology and Laryngological Oncology. The awarded work was written under the supervison of Prof. Małgorzata Wierzbicka, who is the Head of the Clinic and Joanna Jackowska M.D., Ph.D. The third prize went to Dr Michał Prendecki, who is preparing a doctoral dissertation at PUMS Department and Clinic of Neurology (Head: Prof. Wojciech Kozubski). The work presented at the symposium was prepared in the Laboratory of Neurobiology and supervised by Prof. Jolanta Dorszewska, who tutors Dr Prendecki's doctoral thesis.
Pengaruh Environmental Performance, Corporate Governance, dan Firm Age Terhadap Environmental Disclosure
Authors: Annisa Widyastuti  , Rida Prihatni  , Diah Armeliza  
Published: March 2024

Abstract

The study was conducted with the aim of finding out the effect environmental performance, independent commissioners, institutional ownership and firm age on environmental disclosure. The sample selection technique was used purposive sampling and obtained a sample of 30 companies from manufacturing, agriculture and mining companies listed on the Indonesia Stock Exchange in 2017-2020. Data analysis for hypothesis testing in this study used panel data regression analysis with Eviews 12. The results of this study show that environmental performance, institutional ownership and firm age have a positive effect on environmental disclosure While independent of commissioners has no effect on environmental disclosure.
Keywords: Environmental Performance, Independent Commissioners, Institutional Ownership, Firm Age, Environmental Disclosure.

Abstrak

Penelitian ini memiliki tujuan yaitu mengetahui pengaruh kinerja lingkungan, komisaris independen, kepemilikan institusional dan umur perusahaan terhadap pengungkapan lingkungan. Teknik pemilihan sampel menggunakan purposive sampling dan terpilih 30 perusahaan dari perusahaan manufaktur, pertanian dan pertambangan yang terdaftar di Bursa Efek Indonesia tahun 2017-2020. Analisis data untuk pengujian hipotesis dalam penelitian ini menggunakan analisis regresi data panel dengan Eviews 12. Penelitian ini menghasilkan bahwa kinerja lingkungan, kepemilikan institusional dan umur perusahaan berpengaruh positif terhadap pengungkapan lingkungan sedangkan komisaris independen tidak berpengaruh terhadap pengungkapan lingkungan.
Kata Kunci: Kinerja Lingkungan, Komisaris Independen, Kepemilikan Institusional, Pengungkapan Lingkungan
Effects of Stepdown Pressure and Wettability on Bubble Nucleation in Gas-Supersaturated Oil-Water Systems
Authors: Pradhan Sushobhan , Bikkina Prem Kumar 
Published: March 2024

Summary
This study investigates the influences of wettability and stepdown pressure on pressure-driven bubble nucleation within a gas-supersaturated oil-water system. Two gases—carbon dioxide (CO2), which is highly soluble in water, and methane (CH4), which is sparingly soluble in water—were used individually for the bubble nucleation experiments. Equal heights of oil (n-decane) and water, in a wettability-controlled glass vial placed in a saturation cell, were saturated with either of the gases at 6000-mbar pressure, followed by applying a stepdown pressure of either 6000 mbar, 500 mbar, or 100 mbar to start the bubble nucleation process. The average bubble nucleation pressures for CO2 and CH4 gases on a hydrophobic vial surface with 500-mbar stepdown pressure were 4333 ± 289 mbar and 3833 ± 289 mbar, respectively. It is important to note that the bubble nucleation took place exclusively on the portion of the solid surface submerged in water. However, bubble nucleation did not take place with 100-mbar stepdown pressure for either gas in the hydrophobic vial despite the pressure being brought down to atmospheric pressure. As expected, bubble nucleation did not take place in the hydrophilic vial for the gases despite the pressure being brought down to atmospheric pressure from the saturation pressure, regardless of the stepdown pressure. In addition, bubble nucleation did not take place in CO2-supersaturated water in the oil-wetted hydrophilic and hydrophobic vials, even at maximum supersaturation.
Molecular Cloning of Saslah3, a Novel Slow Anion Channel Slac/slah Family Gene, From Euhalophyte Suaeda Altissima (L.) Pall and Analysis of the Encoded Protein
Authors: Rostovtseva Helen , Khramov Dmitry E. , Myasoedov Nikolai A. , Lobreva Olga V. , Khalilova Lyudmila A. , Tarakanov Ivan G. , Karpichev Igor V. , Balnokin Yurii V. 
Published: March 2024

Abstract

Cloning of the SaSLAH3 gene (OQ271227.1), an AtSLAH3 ortholog from the slow anion channels family (SLAC/SLAH), that was originally identified in Arabidopsis thaliana, has been carried out from the euhalophyte Suaeda altissima. Under hydroponic conditions, this species related to Amaranthaceae/Chenopodiaceae is capable to complete life cycle on nutrient solutions containing NaCl at high concentrations up to 1 M. Cloning of SaSLAH3 was performed based on a putative similarity of SaSLAH3 with the SLAH3 homologs from the related species Suaeda glauca and Suaeda fruticosa, using transcriptomes assembled previously. Membrane topology, analyzed by in silico approach, the 3-D structure, presence of conservative phenylalanine-bearing motives and as well as MEME-generated sequence motif patterns of SaSLAH3, all of these features were found typical for the SLAC/SLAH channels and had validated SaSLAH3 belonging to this family. Analysis of SLAC/SLAH phylogenetic relationship demonstrated the evolutionary divergence of SLAC-like proteins into three distinct groups characteristic of this family with location of SaSLAH3 in SLAH2/3 clade. Investigation of the expression profile by quantitative Real-Time PCR revealed increasing SaSLAH3 expression in roots and leaves upon elevation of NaCl concentration in nutrient solution under conditions of both sufficient nitrate supply and nitrate deficiency. SaSLAH3 is suggested to play an important role in enhancing chloride loading into root xylem and, thereafter in chloride delivery to shoot under salinity. Another physiological role of SaSLAH3 may be attributed to regulation of nitrate concentration in cytoplasm to ensure proper nitrogen nutrition of S. altissima plants under conditions of stiff competition of nitrate with chloride.
A Mechanical Origin of Cooperative Transport
Authors: Zion Matan Yah Ben , Arbel Eden , Oppenheimer Naomi , Lahini Yoav 
Published: March 2024

Abstract

Cooperative transport is a striking phenomenon where multiple agents join forces to transit a
payload too heavy for the individual. While social animals such as ants are routinely observed to
coordinate transport at scale [1–5], reproducing the effect in artificial swarms remains challenging, as it
requires synchronization in a noisy many-body system [6–27]. Here we show that cooperative transport
spontaneously emerges in swarms of stochastic self-propelled agents, without requiring any form of
sensing, feedback, or control. We show that a minute modification to the mechanical design of the
individual agent dramatically changes its alignment response to an external force. We experimentally
demonstrate that with the proper design, a swarm of active particles spontaneously cooperates in the
directional transport of larger objects. Surprisingly, transport increases with increasing payload size.
A mechanical, coarse-grained description reveals that force-alignment is intrinsic and captured by
a signed, charge-like parameter with units of curvature. Numerical simulations of swarms of active
particles with a negative active charge corroborate the experimental findings. We analytically derive
a geometrical criterion for cooperative transport which results from a bifurcation in a non-linear
dynamical system. Our findings generalize existing models of active particles [28–37], offer new design
rules for distributed robotic systems, and shed light on cooperative transport in natural swarms.
Influence of germination time on the morphological, structural, vibrational, thermal and pasting properties of potato starch from Solanum tuberosum Phureja group
Authors: Lucas-Aguirre Juan Carlos , Quintero-Castaño Víctor Dumar , Henao-Ossa Johan Sebastián , Barrón-García Oscar Yael , Rodríguez-García Mario Enrique 
Published: March 2024

Abstract

This work focuses on the study of the physico-chemical changes that take place during a short germination period in flours and starches of Creole potato. To this end, the changes in the composition of the flours and the structural, thermal, vibrational, functional and pasting changes of the germinated starches were evaluated during the 12-day germination period, which was measured every 4 days. The water absorption index (WAI) and swelling powder showed no significant changes. Germination resulted in a decrease in fat and ash content, but an increase in protein and amylose content. Scanning electron microscopy (SEM) showed no changes in the morphology of the starch during germination. X-ray diffraction showed that this starch contains nanocrystals with hexagonal crystal structure, which are not affected by germination. Differential scanning calorimetry (DSC) shows a shift of the gelatinization peak to the right, which could be attributed to the concentration effect. The pasting profiles of the isolated starches show no significant changes, indicating that the potato endosperm does not undergo any changes during germination and the final viscosity behaves like a hydrogel.