bluuebunny/crossref_metadata_2025_split huggingface dataset:
The prevalence of job satisfaction and its associated factors among medical intern students in University of Gondar comprehensive specialized hospital, Gondar, Ethiopia 2022
Authors: Abebe Tesfaye Birhanu , Balcha Thomas Daba , Melkam Yalew , Andualem Zewudu , kassa Tewodros , Desyalew Tigist , Alemayehu Tekletsadik Tekleslassie , Wassie Yilkal Abebaw 
Published: April 2024

Abstract

Introduction: By considering the importance of job satisfaction to Interns’ well-being and to quality of care, it is important to investigate factors that contribute to or decrease job satisfaction. Although many studies have been conducted worldwide to find out the prevalence of job satisfaction among doctors, yet very few have been conducted in Ethiopia, especially regarding medical interns.
Objective: This study was aimed to assess the prevalence of job satisfaction and its associated factors among medical intern students in University of Gondar comprehensive specialized hospital, Gondar, Ethiopia 2022.
Method: An institution based cross-sectional study was conducted on 320 study participants from November 05-15, 2022. All medical interns registered in 2022 was assessed by using conventional sampling method and data were collected by using pre-tested and structured self-administered questionnaire. Data were entered into Epi-INFO version7 and exported to SPSS version 25.0 for analysis. Logistic regression were carried out to recognize factors associated with medical intern job satisfaction. Adjusted odds ratio with a 95% confidence interval were used to measure the strength of association. Variables having p-value less than 0.2 in bivariable analysis were entered in to multivariable analysis; variables with a p-value< 0.05 were declared significantly associated with job satisfaction.
Results: The overall level prevalence of job satisfaction among medical interns was found to be 32.2% 95%. Being male [AOR=1.84; (1.02, 3.34)], working department [AOR=2.53; (1.2, 5.30)], place of origin [AOR=1.80; (1.01, 3.20)], and number of duties [AOR=2.98; (1.17, 7.59)] factors were significantly associated with job satisfaction.
Conclusion: The prevalence of job satisfaction among medical interns was found to be high. Being male, place of origin, working department, and number of duty were statistically significant associated factors. Its better, managers and policy makers should give due considerations on medical interns’ job satisfaction if they genuinely want to attain institution’s objectives.
Comparison of CROES, Guy's, S.T.O.N.E., and S-ReSC Nephrolithometric Scoring Systems in Predicting Success and Complications in Patients Undergoing Supine Mini Percutaneous Nephrolithotomy
Authors: Ayranci Ali , Erbin Akif , Caglar Ufuk , Meric Arda , Gunay Nazim Furkan , Sarilar Omer 
Published: April 2024

Abstract

In addition to the fact that the significance of the nephrolitometric scoring systems (NSSs) remains unclear, no study has been conducted to assess the effectiveness of these scoring systems in percutaneous nephrolithotomy (PNL) performed in the supine position. We aimed to compare the CROES, Guy's scoring system (GSS), S.T.O.N.E., and S-ReSC NSSs for success and complications in patients undergoing supine mini-PNL (m-PNL). The prospectively recorded data of the patients who underwent supine m-PNL was reviewed retrospectively, and a total of 112 patients were included in the study. Demographic, operation, post-procedure data, and CROES, GSS, S.T.O.N.E., and S-ReSC scores were assessed and compared between the stone-free (SF) and residuel groups. There were significant differences between the SF and residual groups in terms of mean CROES, S.T.O.N.E., and S-ReSC scores (p = 0.003, p = 0.009, and p = 0.015, respectively). Similarly, there were significant differences between the grades of these scoring systems and the success of the procedure (p = 0.035, p = 0.007, and p = 0.007, respectively). However, the GSS was insignificant. The area under curve values in ROC analysis of CROES, S.T.O.N.E., and S-ReSC NSSs were 0.695, 0.665, and 0.656, respectively (p = 0.003, p = 0.011, and p = 0.017, respectively). No statistically significant difference was found between the grades of all four NSSs and the complication rates. The study showed a strong correlation between CROES, STONE, and S-ReSC NSSs in predicting SF status after supine m-PNL. However, none of the NSSs could predict the complications.
Anatomical characteristics of mitral isthmus and its spatial relationship with the esophagus in patients undergoing atrial fibrillation ablation using CT angiography
Authors: Pan Yilin , Zeng Hong , Liu Xin , Fu Xiaohang , Pan Liyuan , Wang Yanjing 
Published: April 2024

Abstract

Background
This study examines the anatomical characteristics of the mitral isthmus (MI) and its spatial relationship with the esophagus in patients undergoing atrial fibrillation ablation, using cardiovascular computed tomographic angiography (CTA). Understanding this relationship is crucial to minimize the risk of esophageal injuries during ablation procedures.
Methods
The investigation included 300 participants, divided into 200 subjects in the experimental group undergoing atrial fibrillation ablation and 100 in the control group. Detailed CTA scans were used to assess the MI's structure and proximity to the esophagus, employing various measurements like the MI's endocardial length, depth, and its relation to adjacent esophageal anatomy.
Results
The study revealed significant differences in the MI's length and distance measurements between the experimental and control groups, with the former showing greater dimensions, potentially influencing ablation strategies. A substantial proportion of patients exhibited close proximity or direct contact between the MI and the esophagus, emphasizing the importance of pre-procedural imaging in identifying risks for esophageal damage.
Conclusions
Pre-procedural cardiovascular CTA provides essential insights into the MI's anatomical details and its relation to the esophagus, aiding in the customization of ablation strategies to enhance procedural safety and efficacy. The findings highlight the significance of tailored imaging assessments to mitigate esophageal injury risks in atrial fibrillation ablation.
Bio-Nano Sensor utilizing Single-Layer Graphene for the Detection of Iridovirus
Authors: Makwana Manisha , Patel Ajay M 
Published: April 2024

Abstract
Context:
Graphene and its related compounds have remarkable optical, electrical, and chemical characteristics that make them suitable for biosensing. Nondestructive biological molecule identification is made possible by biosensors based on graphene and its derivatives. The field of biological sensors is expanding to meet the demand for sensitive early detection of disorders. The aim of the present investigation is to develop a sensor by analyzing the vibrational responses of single layer graphene sheets (SLGS) with attached microorganisms, specifically Iridoviridae. Graphene-based virus sensors typically rely on the interaction between the virus and the graphene surface, which lead to changes in the frequency response of graphene. This change can be measured and used to detect the presence of the virus. Its high surface-to-volume ratio and sensitivity to changes in its frequency make it a highly sensitive platform for virus detection.
Methods:
The atomistic finite element method (AFEM) has been used to carry out for dynamic analysis of SLG. Molecular structural analysis has been performed for single-layer graphene. Bridged and simply supported with roller support boundary conditions applied at the ends of SLG structure. Simulations have been performed to see how SLG behaves when used as sensors for biological creatures. A single-layer graphene armchair SLG (5, 5) with 50 nm length, exhibits its highest frequency vibration at 8.66 x 106 Hz, with a mass of 1.2786 Zg. In contrast, a zigzag- SLG with a (18,0) configuration has its lowest frequency vibration at 2.82 x 105 Hz, observed at a length of 10 nm. Finite Element Method (FEM) analysis is utilized to forecast the performance of single-layer graphene (SLG) biosensors under simply supported with roller support and bridged boundary conditions. This aids in comprehending the thresholds of detection and the influence of factors such as size, chirality, and boundary conditions on sensor effectiveness. These biosensors can be especially helpful in biological sciences and the medical field since they can considerably improve the treatment of patients, cancer early diagnosis, and pathogen identification when used in clinical environments. By simulating sensor behavior using FEM, researchers can reduce the need for costly and time-consuming experimental testing, speeding up the development process.
Virulence Plasmid with IroBCDN Deletion Promoted Cross-regional Transmission of ST11-KL64 Carbapenem-resistant Hypervirulent Klebsiella Pneumoniae in Jiangxi Province, China
Authors: Huo Bing-Hui , Hong Hanxu , Xu Ying , Xiang Tian-xin , Wei Dan-Dan , Huang Qi-Sen , Liu Peng , Zhang Wei , Liu Yang 
Published: April 2024

Abstract

Background Carbapenem-resistant and hypervirulent Klebsiella pneumoniae (CR-hvKP) caused infections of high mortality and brought a serious impact on public health. This study evaluated the transmissibility of CR-hvKP among different regions to provide corresponding advice for cross-regional prevention.
Methods Clinical K. pneumoniae strains were collected from Jiujiang region and Nanchang region in Jiangxi province from November 2021 to June 2022. We characterized these strains for their genetic relatedness, virulence phenotype, and dissimilarities in virulence plasmid structures using PFGE, Galleria mellonella, Whole-genome sequencing. Conjugation assay was performed to evaluate the transmissibility of virulence plasmids.
Results Among 609 strains, 45 (7.4%) CR-hvKP were identified, while the strains
isolated from Nanchang and Jiujiang accounted for 10.05% (36/358) and 3.59% (9/251). We observed that ST11-KL64 CR-hvKP had an overwhelming epidemic dominance in these two regions. Significant genetic diversity was identified among all ST11-KL64 CR-hvKP cross-regional transmission between Nanchang and Jiujiang serving as major drivers of clonal clusters. Virulence genes profile revealed that ST11-KL64 CR-hvKP might harbour incomplete pLVPK-like plasmids and primarily evolved from CRKP by acquiring the hypervirulence plasmid. We found the predominance of truncated-IncFIB/IncHI1B type virulence plasmids with a 25kb fragment deletion that encoded iroBCDNclusters. Virulence plasmids harbored in CR-hvKP isolates with iroBCDN deletion fragment exhibited a higher conjugation success rate and efficiency.
Conclusions ST11-KL64 is the most cross-regional prevalent type CR-hvKPs in Jiangxi province, which mainly evolved from CRKPs by acquiring a truncated-IncHI1B/IncFIB virulence plasmid with the deletion of iroBCDN. Stricter surveillance and control measures are urgently needed to prevent the epidemic transmission of ST11-KL64 CR-hvKP.
Evaluation of left atrial dysfunction in pediatric and adult patients with repaired tetralogy of Fallot using two- dimensional speckle-tracking echocardiography
Authors: Sato Keiya , Takahashi Ken , Akatsuka Yusuke , Sato Hiroyuki , Kago Hirohisa , Akiya Azusa , Akimoto Satoshi , Ifuku Mayumi , Hosono Yu , Shigemitsu Sachie , Matsui Kotoko , Nakanishi Keisuke , Kawasaki Shiori , Shimizu Toshiaki 
Published: April 2024

Abstract

Purpose: Although the left atrium (LA) plays a key role in diastolic function, LA dysfunction in patients with repaired tetralogy of Fallot (rTOF) remains unclear. Therefore, we aimed to evaluate left atrial function and investigate changes with age in patients with rTOF using speckle-tracking echocardiography.
Methods: We compared 62 patients with rTOF with 62 healthy similar age- and sex-matched controls divided into three age groups (T1, C1: 3–9 years [children], T2, C2: 10–19 years [adolescents and young adults], and T3, C3: 20–44 years [adults]). LA strain was assessed by two-dimensional speckle-tracking echocardiography and defined according to its three distinct phases, with the LA serving as a reservoir during systole, conduit during early diastole, and booster pump at the end of diastole.
Furthermore, we examined the correlations between LA strains and left ventricular longitudinal strain (LVLS) and conventional echocardiographic parameters.
Results:The LA reservoir and pump strains were lower in the T3 group than in the C3 group. In T1 and T2 groups, no significant differences in any LA strains were reported. LA functions based on LA volume did not show any difference between TOF and controls among all age groups. All LA strains only moderately or weakly correlated with LVLS and mitral E/A, but not with LV lateral e’ nor E/e’.
Conclusions: LA phasic function decreases in adult patients with rTOF. These parameters can potentially be used as sensitive indicators of diastolic dysfunction in patients with rTOF.
Fish consumption in relation to breast cancer: A case-control study
Authors: Akhgarjand Camellia , Fogacci Federica , Benisi-Kohansal Sanaz , Houjaghani Hirad , Azadbakht Leila , Esmaillzadeh Ahmad 
Published: April 2024

Abstract

Background: Even though regular fish consumption is highly recommended to reduce the risk of developing several cancers, available evidence on the association between breast cancer and fish is inconclusive. We aimed to explore the association between fish consumption and breast cancer in a well-characterized population of Iranian women.
Methods: This study enrolled 350 newly diagnosed stage I-IV breast cancer patients and 700 cancer-free controls living in Isfahan. Controls had no family history of breast cancer and were matched to cancer patients in term of age and socioeconomic status (SES). Dietary intakes were determined using a validated food frequency questionnaire (DS-FFQ). In addition, data on potential confounding factors were collected using pre-tested questionnaires.
Results: After adjusting for potential confounders, women in the highest quartile of fish consumption had a lower odds of breast cancer than those in the lowest quartile (OR: 0.57, 95% CI: 0.34-0.95). The stratified analysis by menopausal status revealed an inverse association in postmenopausal women (OR: 0.53, 95% CI: 0.30-0.94).
Conclusions: Our findings suggest higher fish consumption is associated with a lower likelihood of having breast cancer, particularly in post-menopause. The findings should be interpreted with caution due to the case-control study design. To further examine this association, prospective studies are needed.
Trace metals pollution and trophic position of three sea urchin species in the Gulf of California
Authors: Acosta-Pachón Tatiana A. , López-Vivas Juan Manuel , Mazariegos-Villareal Alejandra , Méndez-Rodríguez Lía C. , León-Cisneros Karla , Martínez-Rincón Raul O. , Serviere-Zaragoza Elisa 
Published: April 2024

Abstract

Sea urchin species are ecologically important in the Gulf of California and are becoming popular as a local fishery due their commercial value. The most abundant species are Echinometra vanbrunti, Eucidaris thouarsii, and Tripneustes depressus. The aim of this study was to evaluated cadmium, lead, copper, zinc, and iron concentrations as well as stable isotope values in these sea urchin species in mining area of Santa Rosalia (STR). Metal concentrations were analyzed by atomic absorption spectrophotometry and stable nitrogen and carbon isotopes were estimated using mass spectrophotometry. Highest values of Fe (108.8 mg Kg−1), was found in E. vanbrunti, while highest values of Pb (15.4 mg Kg−1), Cu (14.5 mg Kg−1), and Zn (347.7 mg Kg−1) were found in E. thouarsii; and highest values of Cd (10.8 mg Kg−1) was found in T. depressus. The main ecological risk of trace metal pollution in STR may be caused by Cd and Pb. d15N values were higher in E. thouarsii and d13C in T. depressus, and E. thouarsii have the highest trophic position. There is not relationship between size and metal concentrations, but a positive relation exists between size and isotopic values in T. depressus. The three species showed different bioaccumulation pattern for the metals analyzed. Additionally, collection site and season play an important role in the metal concentration variability. Given that these species are consumed by humans, some risk of trace metals toxicity could be expected due to the accumulation patterns and characteristics of the sites studied.
The Impact of Childhood Obesity on Traumatic Injury Outcomes
Authors: Lewis Briana T. , Leung Willie , Olsen Rebecca , Nelson Julie , Casatelli Jennifer 
Published: April 2024

Abstract
Introduction
Globally, traumatic injury and obesity are significantly linked to pediatric health. The relationship between traumatic injury outcomes and childhood obesity remains poorly understood. This study assesses the potential correlation between childhood obesity and patient outcomes following trauma injuries, with a particular focus on elucidating the intricate interplay among childhood obesity, trauma injury outcomes, and patterns of healthcare utilization, which will address the gap in literature and lays the groundwork for further investigation into the complex relationship between childhood obesity and traumatic injury outcomes.
Methods
The current study is a retrospective cohort study analyzing data from St. Jospeh’s Children’s Hospital’s Emergency and Trauma Center in Tampa, Florida, between 2010 to 2021. Participants aged 2 to 18 were included and stratified by obesity categories, normal weight, overweight, and obese, based on their BMI. Associations between obesity categories and trauma outcomes such as Length of Hospital Stay (LOS), days in Intensive Care Unit (ICU), Injury Severity Score (ISS), and mortality were examined.
Results
Among 1965 participants, 48.85% of participants were of normal weight, 19.49% were overweight, and 31.65% were obese. No significant differences in the included trauma outcomes across obesity classifications were found among analyses. Linear regressions showed no association between trauma outcomes and obesity (P>.05). Mortality outcomes were not analyzed due to insufficient data on deceased participants (P>.05).
Conclusion
Childhood obesity did not independently predict adverse trauma outcomes in this study. The findings challenge previous assumptions and emphasize the multifactorial nature of trauma outcomes in pediatric patients. Further research with larger sample sizes and comprehensive data collection is needed to fully understand this relationship.
LEVEL OF EVIDENCE
Level V, Retrospective cohort study
A New Method of Archaeological Ruins Identification Based on CORONA Stereo Pairs
Authors: Zhang Yixin , Wang Ningyuan , He Jie , Zhang Tao , Zhang Xin , Luo Hongpeng 
Published: April 2024

Abstract
Three-dimensional (3D) stereo images can be generated via the computer-based image processing of CORONA stereo pairs. To a certain extent, important terrain and surface feature data extracted from these stereo images can improve the survey of archaeological sites and the identification and mapping of major landscapes. This study focuses on the identification of the Archaeological Ruins of Liangzhu City. An optical stereo model (red/blue stereo image) of the Liangzhu site was created through the computer-based mosaicking and processing of CORONA remote-sensing stereo pairs taken in the 1960s and 1970s. By importing the optical stereo model into mobile phones, tablet computers, and other mobile devices, the research team undertook real-time locating via human observation, on-site investigation, and image overlayduring field survey and identified several Liangzhu-period dams, some of which have been confirmed via archaeological field investigations. The research team later applied the same method to the identification of tombs in the site of the Mausoleums of the Six Emperors of the Southern Song Dynasty. The results further proved that this method is feasible and reliable and can be widely promoted and used for the identification of archaeological ruins.
Frailty in older adults admitted to hospital: outcomes from the Western Sydney Clinical Frailty Registry.
Authors: McDonagh Julee , Lindley Richard I , Byth Karen , John Reejamol , Ferguson Caleb 
Published: April 2024

Abstract

Objectives
To report the baseline profile, clinical management, all-cause rehospitalisation, and mortality at 12 months of adults enrolled into the Western Sydney Clinical Frailty Registry.
Design:
Prospective observational cohort study
Setting and Participants:
592 adults admitted to an acute geriatric medicine service in NSW, Australia, were included in this study.
Methods
The Western Sydney Clinical Frailty Registry is a study of adults admitted to acute geriatric wards in a 570-bed two-site district general hospital in Western Sydney NSW, Australia. Recruitment began in April 2020 and is ongoing. Each participant is recruited while an inpatient and followed up for 12 months including baseline visits and three-, six- and 12-month follow-ups via telephone interviews. The primary outcome of this study was rehospitalisation and/or mortality at 12 months.
Results
Median age 82 years; half the cohort were classified as mild-moderately frail and 21% were classified as severely frail. A total of 134 participants died (22.6%) within the 12-month follow-up period. Increased cumulative incidence of first rehospitalisation and/or death during the first 12 months post-discharge was significantly associated with higher modified Charlson comorbidity (p < 0.001) and Clinical Frailty Scale (CFS) scores (p < 0.001). Compared to the ‘non-frail’ group (CFS 1–4), those who were severely frail (CFS 7–9) had an 85% increased risk of rehospitalisation and/or death, and those who were mild-moderately frail (CFS 5–6) had a 52% increased risk after adjusting for effects of the other variables.
Conclusions
Frailty is very common in older adults admitted to acute geriatric services. Assessing frailty using the CFS is feasible and is independently predictive of rehospitalisation and mortality. Our findings suggest that integrating frailty assessment into clinical practice goes beyond simple risk stratification, offering valuable insights for tailored clinical management strategies.