bluuebunny/crossref_metadata_2025_split huggingface dataset:
Analisis Minat Belajar Siswa pada Pembelajaran IPA Menggunakan Modul Pembelajaran IPA berbasis Potensi Lokal
Authors: Sugianto Ferdy 
Published: February 2025

Salah satu komponen penting untuk mendukung keberhasilan pembelajaran adalah bahan ajar. Berdasarkan hasil wawancara yang dilakukan pada beberapa sekolah di Kabupaten Banyuwangi, didapatkan bahan ajar yang digunakan berasal dari pemerintah masih sulit untuk di pahami siswa. Hal ini dikarenakan bahan ajar yang digunakan berasal dari pemerintah hanya berisi materi dan soal latihan dengan tampilan yang kurang menarik, sehingga minat belajar siswa masih rendah. Penelitian ini bertujuan untuk menganalisis minat belajar siswa terhadap kegiatan pembelajaran IPA menggunkan modul pembelajaran IPA berbasis kearifan lokal. Dari penelitian didapatkan nilai minat belajar siswa pada indikator yang pertama yaitu 85 dengan kriteria sangat baik. Indikator kedua yaitu 83,5 dengan kriteria sangat baik. Indikator yang ketiga yaitu 76,5 dengan kriteria baik. Indikator keempat yaitu 81 dengan kategori sangat baik. Dan nilai rerata minat belajar siswa mendapatkan presentase 81,5 dengan kategori sangat baik. Dari hasil tersebut dapat disimpulkan bahwa pembelajaran IPA menggunkan modul pemebelajaran IPA berbasis kearifan lokal berpengaruh positif terhadap minat belajar siswa.
Pendidikan Konservasi Bagi Siswa-Siswi SMTKN Diaspora Kabupaten Sorong
Authors: Wattimena Lanny , Serkadifat Yetti S. , Turot Amatus , Maay Herna , Alfons Burmanus , Masauna Risna 
Published: February 2025

Pendidikan Konservasi merupakan usaha dalam menjaga keanekaragaman hayati yang bertujuan untuk mengenalkan alam kepada masyarakat sedini mungkin dan meningkatkan kesadaran mengenai alam di sekitar kita termasuk juga masalah-masalah yang ada, serta memahami nilai-nilai penting dan luhur mengenai sumber daya alam dan juga ekosistem yang ada. Sebagian besar masyarakat di Indonesia dan di Papua Barat Daya pada khususnya, masih belum memiliki perilaku peduli lingkungan, seperti masih banyaknya masyarakat yang membuang sampah tidak sesuai dengan jenisnya antara tempat sampah organik dan anorganik. Sehingga perlu dilakukannya kegiatan sosialisasi tentang pendidikan konservasi bagi masyarakat khususnya pada anak-anak. Dengan demikian kami dari Program Studi Kehutanan Fakultas Ilmu Pertanian dan Lingkungan Universitas Victory Sorong merasa tertarik untuk melaksanakan Sosialisasi tentang “Pendidikan Konservasi Bagi Siswa-siswi SMTKN Diaspora Kabupaten Sorong”, dengan tujuan untuk mengubah perilaku dan sikap, serta meningkatkan pengetahuan, keterampilan dan kesadaran siswa-siswi tentang nilai-nilai lingkungan dan isu permasalahan lingkungan, yang pada akhirnya dapat berperan aktif dalam upaya pelestarian dan keselamatan lingkungan untuk kepentingan generasi sekarang dan yang akan datang. Materi sosialisasi terdiri dari pengertian, tujuan, dan manfaat konservasi, upaya-upaya konservasi, serta contoh kawasan konservasi yang ada di Provinsi Papua Barat Daya. Kegiatan sosialisasi ini mendapat respon yang sangat baik dari pihak sekolah, dan diharapkan memberikan manfaat bagi siswa-siswi untuk mengetahui pentingnya pendidikan konservasi sejak dini untuk mengubah perilaku dan sikap dalam meningkatkan pengetahuan, keterampilan dan kesadaran tentang pentingnya menjaga kelangsungan hidup keragaman spesies, menjaga dan melindungi ekosistem agar tetap indah, menarik dan unik, serta dapat memanfaatkan lingkungan seefisien mungkin.
"There is no shakier reflection of the word...": Shakespeare in the translations of Tatiana Shchepkina-Kupernik
Authors: Liubivaia Irina Yur'evna 
Published: February 2025

The author considers the translation of drama as a kind of literary translation. The author proceeds from the premise that dramatic translation is a type of literary translation that is dialogical in nature: it contains both literary and theatrical elements, in other words, in addition to the requirements imposed on the literary text, it must comply with the laws of the stage and the direction of the word. In the article, the author distinguishes the text as literary and theatrical material. Special attention is paid to the description of Tatiana Shchepkina-Kupernik's translation work in the field of drama. Using the example of individual scenes from Romeo and Juliet, the author examines the purposeful use of dialectal forms and jargon as an integral part of the author's idiosyncrasy, attention to rhyme and preservation of rhythm, and adaptation of the text for its subsequent pronunciation in a theatrical setting. The article uses the method of analytical study of sources. Based on archival materials, which are being introduced into scientific circulation for the first time, the relationship between Shchepkina-Kupernik and theater directors in the process of working on dramatic translations and their further stage implementation is considered; the translator's initial attitude to the person's perception of the translated of the literary text is revealed. The author concludes that in her work on dramatic translations of Shakespeare, T. L. Shchepkina-Kupernik considered the main thing not only to maximize the preservation of the author's style, balance, clarity in the transmission of meanings and images, but also to preserve the possibility of the scenic embodiment of the author's idea and its nature. Also, the translator paid special attention to the interpretation of words. Of particular research interest are the comments of Maria Knebel, an outstanding Soviet director, on the translation of Shakespeare's comedy "As You Like It". Based on individual memoir sources, the Shchepkina-Kupernik translation principles are revealed, thanks to which the director and actors get the opportunity to work with ready-made dramatic material that does not require literary refinement for convincing presentation in stage conditions.
Salt Literacy and Educational Disparities in Rural Bayelsa State, Nigeria
Authors: Zibima Soupriye Bidokumo , Oniso Juliet Imawaigha 
Published: February 2025

Aims: To assess salt literacy levels among adults in remote communities of Bayelsa State and examine its association with educational attainment.
Study Design: The study was a community-based cross-sectional survey.
Place and Duration of Study: Conducted in selected communities in the creeks of Bayelsa between September 2023 and April 2024.
Methodology: The study included 2,016 respondents selected purposively from nine communities in the creeks of the three senatorial districts of Bayelsa State. A validated salt literacy questionnaire was used to obtain salt literacy data. Descriptive statistics were used to obtain summaries of demographic and salt literacy data, while independent samples t-test and chi-square tests were used to determine district-based differences in salt literacy scores and the association between educational status and salt literacy level, respectively.
Results: Female respondents accounted for 57.2%, while males made up the remaining 42.8%. The average sample age was 39 (SD±7.2). A total of 1,655 (82.1%) respondents had low salt literacy, while 62 (3.1%) and 299 (14.8%) had moderate and high salt literacy, respectively. Salt literacy scores were not significantly different among communities in the three senatorial districts (M1 = 24 [SD 5.26], M2 = 24[SD = 5.04]; M3 = 24; [SD = 5.37]); t (2,016) = 2.19, P = 0.104, 2-tailed). There was also no significant association between respondents’ educational status and salt literacy level (χ² = 0.237, df = 3, P = 0.124).
Conclusion: Salt literacy level is low among adults in remote communities of Bayelsa State, and no significant association exists between educational status and salt literacy. The findings underscore the need for targeted health education interventions to improve salt literacy in these communities, focusing on addressing knowledge gaps regardless of educational attainment.
Genetic and Phenotypic Features of Schizophrenia in the UK Biobank
Authors: Legge Sophie E. , Pardiñas Antonio F. , Woolway Grace , Rees Elliott , Cardno Alastair G. , Escott-Price Valentina , Holmans Peter , Kirov George , Owen Michael J. , O’Donovan Michael C. , Walters James T. R. 
Published: March 2024

ImportanceLarge-scale biobanks provide important opportunities for mental health research, but selection biases raise questions regarding the comparability of individuals with those in clinical research settings.ObjectiveTo compare the genetic liability to psychiatric disorders in individuals with schizophrenia in the UK Biobank with individuals in the Psychiatric Genomics Consortium (PGC) and to compare genetic liability and phenotypic features with participants recruited from clinical settings.Design, Setting, and ParticipantsThis cross-sectional study included participants from the population-based UK Biobank and schizophrenia samples recruited from clinical settings (CLOZUK, CardiffCOGS, Cardiff F-Series, and Cardiff Affected Sib-Pairs). Data were collected between January 1993 and July 2021. Data analysis was conducted between July 2021 and June 2023.Main Outcomes and MeasuresA genome-wide association study of UK Biobank schizophrenia case-control status was conducted, and the results were compared with those from the PGC via genetic correlations. To test for differences with the clinical samples, polygenic risk scores (PRS) were calculated for schizophrenia, bipolar disorder, depression, and intelligence using PRS-CS. PRS and phenotypic comparisons were conducted using pairwise logistic regressions. The proportions of individuals with copy number variants associated with schizophrenia were compared using Firth logistic regression.ResultsThe sample of 517 375 participants included 1438 UK Biobank participants with schizophrenia (550 [38.2%] female; mean [SD] age, 54.7 [8.3] years), 499 475 UK Biobank controls (271 884 [54.4%] female; mean [SD] age, 56.5 [8.1] years), and 4 schizophrenia research samples (4758 [28.9%] female; mean [SD] age, 38.2 [21.0] years). Liability to schizophrenia in UK Biobank was highly correlated with the latest genome-wide association study from the PGC (genetic correlation, 0.98; SE, 0.18) and showed the expected patterns of correlations with other psychiatric disorders. The schizophrenia PRS explained 6.8% of the variance in liability for schizophrenia case status in UK Biobank. UK Biobank participants with schizophrenia had significantly lower schizophrenia PRS than 3 of the clinically ascertained samples and significantly lower rates of schizophrenia-associated copy number variants than the CLOZUK sample. UK Biobank participants with schizophrenia had higher educational attainment and employment rates than the clinically ascertained schizophrenia samples, lower rates of smoking, and a later age of onset of psychosis.Conclusions and RelevanceIndividuals with schizophrenia in the UK Biobank, and likely other volunteer-based biobanks, represent those less severely affected. Their inclusion in wider studies should enhance the representation of the full spectrum of illness severity.
Technical note: A comparison of physician doses in C‐Arm and CT fluoroscopy procedures
Authors: Troville Jonathan , Knott Emily , Reynoso‐Mejia Carlos Alberto , Wagner Martin , Lee Fred T. , Szczykutowicz Timothy P. 
Published: March 2024

AbstractPurposeWe address the misconception that the typical physician dose is higher for CT fluoroscopy (CTF) procedures compared to C‐Arm procedures.MethodsWe compare physician scatter doses using two methods: a literature review of reported doses and a model based on a modified form of the dose area product (DAP). We define this modified form of DAP, “cumulative absorbed DAP,” as the product of the area of the x‐ray beam striking the patient, the dose rate per unit area, and the exposure time.ResultsThe patient entrance dose rate for C‐Arm fluoroscopy (0.2 mGy/s) was found to be 15 times lower than for CT fluoroscopy (3 mGy/s). A typical beam entrance area for C‐Arm fluoroscopy reported in the literature was found to be 10.6 × 10.6 cm (112 cm2), whereas for CTF was 0.75 × 32 cm (24 cm2). The absorbed DAP rate for C‐Arm fluoroscopy (22 mGy*cm2/s) was found to be 3.3 times lower than for CTF (72 mGy*cm2/s). The mean fluoroscopy time for C‐Arm procedures (710 s) was found to be 21 times higher than for CT fluoroscopy procedures (23 s). The cumulative absorbed DAP for C‐Arm procedures was found to be 9.4 times higher when compared to CT procedures (1.59 mGy*m2 vs. 0.17 mGy*m2).ConclusionsThe higher fluoroscopy time in C‐Arm procedures leads to a much lower cumulative DAP (i.e., physician scatter dose) in CTF procedures. This result can inform interventional physicians deciding on whether to perform inter‐procedural imaging inside the room as opposed to retreating from the room.
The Multiphasic Teeth of Chiton Articulatus, an Abrasion‐Resistant and Self‐Sharpening Tool for Hard Algae Collection
Authors: Montroni Devis , Sarmiento Ezra , Zhao Ruoheng , Dasika Phani Saketh , Connolly John Michael , Wuhrer Richard , Zhang Yugang , Zhernenkov Mikhail , Wang Taifeng , Ramirez‐Santana Brenda Paola , Sheppard Leigh , Avila‐Poveda Omar Hernando , Arakaki Atsushi , Nemoto Michiko , Zavattieri Pablo , Kisailus David 
Published: March 2024

AbstractChiton articulatus is a species of mollusk living in the tropical Pacific intertidal rocky shores of Mexico. This species feeds on solid waste organic sources, including hard crustose algae that grow on rocky substrates, by grazing on them with its radula, a flexible chitinous membrane lined with mineralized major lateral teeth. In this study, the composition, morphology, and resulting mechanics of the mature teeth of this species, which have yet to be examined, are revealed. The results show the presence of multiphasic mature teeth, each consisting of aligned hard magnetite nanoparticles on the leading edge of the tooth underneath which are magnetite lamellae, followed by goethite, lepidocrocite, and eventually hydroxyapatite near the trailing edge. This multiregional structure demonstrates a gradation in hardness as well as different microstructural features integrated with tough interfaces. The combination of these microstructural and phase arrangements results in an abrasion‐resistant tough structure with a self‐sharpening ability. The results of this work will help contribute to developing new bioinspired designs while also helping to understand the evolution and feeding habits of these intriguing invertebrates.
Artificial Vascular with Pressure‐Responsive Property based on Deformable Microfluidic Channels
Authors: Chen Zhenlin , Fan Lei , Chen Shuxun , Zhao Han , Zhang Qiang , Qu Yun , Huang Ya , Yu Xinge , Sun Dong 
Published: March 2024

AbstractIn vitro blood vessel models are significant for disease modeling, drug assays, and therapeutic development. Microfluidic technologies allow to create physiologically relevant culture models reproducing the features of the in vivo vascular microenvironment. However, current microfluidic technologies are limited by impractical rectangular cross‐sections and single or nonsynchronous compound mechanical stimuli. This study proposes a new strategy for creating round‐shaped deformable soft microfluidic channels to serve as artificial in vitro vasculature for developing in vitro models with vascular physio‐mechanical microenvironments. Endothelial cells seeded into vascular models are used to assess the effects of a remodeled in vivo mechanical environment. Furthermore, a 3D stenosis model is constructed to recapitulate the flow disturbances in atherosclerosis. Soft microchannels can also be integrated into traditional microfluidics to realize multifunctional composite systems. This technology provides new insights into applying microfluidic chips and a prospective approach for constructing in vitro blood vessel models.
Lymph Node Targeting Mediated by Albumin Hitchhiking of Synthetic Tn Glycolipid Leads to Robust In Vivo Antibody Production
Authors: Thekke Veettil Keerthana , Jayaraman Narayanaswamy 
Published: March 2024

AbstractTn antigen is a tumor‐associated carbohydrate antigen, which is present prominently on the tumor cell surfaces and attracts an interest in vaccine development. This work demonstrates that a synthetic Tn antigen carrying glycoconjugate forms a complex with circulating albumin, delivers the antigen to lymph nodes (LNs), and leads to the efficient production of antibodies against the antigen. Synthetic Tn antigen glycoconjugate, possessing DSPE‐PEG2000 linker and lipophilic moieties, undergoes micellization in PBS buffer. In the presence of bovine serum albumin (BSA), demicellization of the glycolipid occurs, with a rate constant of 0.18 min−1. In vitro studies show that the glycoconjugate binds preferentially to BSA in the presence of cells. Immunological assessments in mice models reveal the albumin‐enabled delivery of the Tn glycoconjugate to antigen‐presenting cells in the LNs, specifically leading to a robust humoral immune response. ELISA titers show superior binding, with a saturation dilution of 1:51 200 for Tn glycoconjugate, in comparison to that mediated by the Tn‐BSA covalent conjugate with a saturation dilution of 1:6400. Immunohistochemical staining shows delivery of Tn glycoconjugate at the LNs, specifically at the subcapsular sinus and interfollicular areas. The work highlights the potential of albumin‐mediated target delivery strategy for cancer immunotherapies.
Assembled/Disassembled Modular Scaffolds for Multicellular Tissue Engineering
Authors: Yu Xiaopeng , Ma Hongshi , Wang Yufeng , Hao Jianxin , Chen Lei , Gelinsky Michael , Wu Chengtie 
Published: March 2024

AbstractThe behavior of tissue resident cells can be influenced by the spatial arrangement of cellular interactions. Therefore, it is of significance to precisely control the spatial organization of various cells within multicellular constructs. It remains challenging to construct a versatile multicellular scaffold with ordered spatial organization of multiple cell types. Herein, a modular multicellular tissue engineering scaffold with ordered spatial distribution of different cell types is constructed by assembling varying cell‐laden modules. Interestingly, the modular scaffolds can be disassembled into individual modules to evaluate the specific contribution of each cell type in the system. Through assembling cell‐laden modules, the macrophage‐mesenchymal stem cell (MSC), endothelial cell‐MSC, and chondrocyte‐MSC co‐culture models are successfully established. The in vitro results indicate that the intercellular cross‐talk can promote the proliferation and differentiation of each cell type in the system. Moreover, MSCs in the modular scaffolds may regulate the behavior of chondrocytes through the nuclear factor of activated T‐Cells (NFAT) signaling pathway. Furthermore, the modular scaffolds loaded with co‐cultured chondrocyte‐MSC exhibit enhanced regeneration ability of osteochondral tissue, compared with other groups. Overall, this work offers a promising strategy to construct a multicellular tissue engineering scaffold for the systematic investigation of intercellular cross‐talk and complex tissue engineering.
Kinetically Controlled Polyelectrolyte Complex Assembly of microRNA‐Peptide Nanoparticles toward Treating Mesothelioma
Authors: Anderson Caleb F. , Singh Anand , Stephens Tyler , Hoang Chuong D. , Schneider Joel P. 
Published: March 2024

AbstractBroad size distributions and poor long‐term colloidal stability of microRNA‐carrying nanoparticles, especially those formed by polyelectrolyte complexation, represent major hurdles in realizing their clinical translation. Herein, peptide design is used alongside optimized flash nanocomplexation (FNC) to produce uniform peptide‐based miRNA particles of exceptional stability that display anticancer activity against mesothelioma in vitro and in vivo. Modulating the content and display of lysine‐based charge from small intrinsically disordered peptides used to complex miRNA proves essential in achieving stable colloids. FNC facilitates kinetic isolation of the mechanistic steps involved in particle formation to allow the preparation of particles of discrete size in a highly reproducible, scalable, and continuous manner, facilitating pre‐clinical studies. To the best of the authors knowledge, this work represents the first example of employing FNC to prepare polyelectrolyte complexes of miRNA and peptide. Encapsulation of these particles into an injectable hydrogel matrix allows for their localized in vivo delivery by syringe. A one‐time injection of a gel containing particles composed of miRNA‐215‐5p and the peptide PKM1 limits tumor progression in a xenograft model of mesothelioma.
Highly Sensitive and Breathability Flexible Piezoresistive Pressure Sensor Based on Xylon
Authors: Qin Yuxiang , Gao Bo , Zhou Chuan 
Published: March 2024

AbstractIn recent years, the prevalence of cervical spondylosis has been increasing, which is associated with unhealthy posture in daily life, flexible pressure sensors are beneficial in preventing cervical spine disorders. This work is dedicated to developing a flexible, high‐performance, and breathable device to monitor the health of the neck. Here, a flexible pressure sensor with a “sandwich” structure is presented, which incorporates patterned xylon fabric as the substrate and MXene as the sensitive layer. Furthermore, the application of silver nanowires (AgNWs) as the electrode material improves the piezoresistive performance. Combined with an internal elastic encapsulation method (IEEM), the sensor exhibits high sensitivity (1417.9 kPa−1 under pressure below 100 kPa) and a fast response time (30.77 ms). Compared with traditional flexible pressure sensors, the breathability of devices with an all‐fiber structure is nearly seven times higher, which better satisfies the monitoring requirements of long‐term wear. Finally, a wireless system is established by integrating a Bluetooth module and a terminal app. It enables monitoring and sensing of various physiological signals of the neck, as well as identification and alerting of long‐term poor posture such as prolonged neck flexion, showing a potential candidate for the applications of the next‐generation wearable device.
Strong‐Coupling‐Enhanced Raman Spectroscopy (SCERS) in a Cascade Microsphere‐Cavity
Authors: Mi Yanlin , Xu Zhiyang , Zhao Chen , Zhai Tianrui , Zhao Yan , Jiang Yijian , Yan Yinzhou 
Published: March 2024

AbstractSurface‐enhanced Raman spectroscopy (SERS) is a powerful optical technique with high sensitivity to identify analytes down to a single molecule by fingerprinting vibrational information. The strong coupling in microcavities for supermodes with promoted quality factors demonstrates the capability to boost the interaction between photons and molecules for nonlinear effects. Here a strong‐coupling cascade microsphere‐cavity (MC) achieving spontaneous Raman enhancement is reported, for the first time. The cascade MC is composed of two size‐mismatched microspheres, both of which support optical whispering‐gallery modes (WGMs) with significantly different free‐space ranges. The strong coupling between the supported WGMs in the microspheres can be achieved when the quasi‐vernier effect of resonant modes occurs, by which the energy splitting is up to 4 meV. The fast energy transfer between the size‐mismatched MCs therefore increases the quality factor up to 2.1 × 103 for the upper supermode branch. The strong‐coupling cascade MC structure provides an extra enhancement channel for the Au‐based SERS substrate, demonstrating an enhancement factor of Raman intensity (EFRI) up to 2.6 × 1010 for the limit of detection (LoD) down to 10−12 M of 4‐aminothiophenol (4‐ATP). The strong‐coupling cascade MC substrates also exhibit the versatility for identification of multiple analytes for high‐performance Raman trace‐detection applications.