bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Effectiveness of Islamic Economic Law in The Application of the Halal Value Chain (HVC) Ecosystem in the Halal Food and Beverage Industry in Indonesia
Authors: Barri Abdul , Hadiat Hadiat , Al-Hakim Sofian , Hakim Atang Abdul 
Published: March 2024

Indonesia's potential in the halal industry at this time is very calculated, because Indonesia is the country with the largest Muslim population in the world. This role should not only be seen as a captive market, but also should encourage the growth of the halal industry in Indonesia that is able to compete globally. But in reality, currently Indonesia's halal food and beverage industry has not been included in the top 10 countries with the best halal food and beverage performance in the world. Whereas on the other hand, Indonesia actually has a great opportunity to develop halal products in this sector. The purpose of this study is to determine the effectiveness of Islamic economic law in the application of the halal value chain (HVC) ecosystem in the halal food and beverage industry in Indonesia. This research method uses a qualitative type of research with a descriptive analysis approach. The implementation of this researchwas carried out at food and beverage companies in Indonesia. The subject of the study was the Head of General Affairs of halal food and beverage managers and halal food and beverage employees in Indonesia. The subject was taken by purposive sampling. The researcher's goal is to take the problems that exist in the Indonesian halal food and beverage industry by implementing the Halal Value Chain ecosystem<strong>.</strong> Data collection techniques were carried out by observation, interviews, and questionnaires conducted to the Head of General Affairs of the food and beverage industry. The results of this study show that based on data from the Central Stastistic Agency (BPS) related to the Data on the Number of Halal Food and Beverage Exports in 2022 After the implementation of HVC shows that there is an increase in the export process and a reduction in the Import process, this means that the application of HVC in halal food and beverages in Indonesia is very influential so that it can increase the effectiveness of the halal product even though it has not fully run optimally. The supporting factors for the success of HVC are government support, dedicated assets, information technology, human resource management, collaborative partnerships, halal certification and halal traceability
Potential of Bio-Silica From Palm Oil Waste As a Rehabilitation of Dry Marginal Land on Corn (Zea mays L.) Planting
Authors: Agris Soufri Laila  , Kemal Bakhtiar Rahman1  , Safira Azkia  , Muhammad Rafli  , Akasah Wida 
Published: March 2024

Food estate merupakan program unggulan pemerintah dalam mengatasi krisis pangan akibat Covid-19. Program ini menggunakan tanah ultisol yang memiliki kesuburan rendah karena memiliki pH dan silika yang rendah. Penelitian ini bertujuan untuk meningkatkan kesuburan tanah ultisol dengan pemberian pupuk biosilika dari limbah cangkang kelapa sawit agar meningkatkan produktivitas tanaman jagung (Zea mays L.). Penelitian ini menggunakan Rancangan Acak Kelompok (RAK) dengan 5 taraf perlakuan dan 4 ulangan. Perlakuan pemberian pupuk biosilika sebanyak 0 g/polybag(S0) sebagai kontrol, 10 g/polybag (S1), 20 g/polybag (S2), 30 g/polybag (S3), dan 40 g/polybag (S4). Parameter yang diamati pada pupuk biosilika berupa uji FTIR, pada tanah ultisol berupa uji pH, P tersedia, Si tersedia, dan daya hantar listrik (DHL), sedangkan pada tanaman jagung meliputi tinggi tanaman, jumlah daun, bobot kering akar, bobot kering tajuk, dan serapan P. Data diolah menggunakan software IBM SPSS Statistic 25 dan dianalisis menggunakan analisis keragaman (Anova) pada taraf uji 5%. Hasil penelitian menunjukkan bahwa limbah cangkang kelapa sawit mengandung silika sehingga dapat digunakan sebagai pupuk biosilika. Pemberian pupuk biosilika pada tanah ultisol mampu meningkatkan pH dan P tersedia sehingga meningkatkan serapan P dan pertumbuhan tanaman jagung. Perlakuan terbaik diperoleh pada perlakuan pemberian pupuk biosilika sebanyak 30 g/polybag (S3).
ZONASI KESESUAIAN TAMBAK UNTUK PENGEMBANGAN BUDIDAYA UDANG VANAME (Penaeus vannamei) PADA ASPEK KUALITAS AIR DI DESA TODOWONGI KECAMATAN JAILOLO KABUPATEN HALMAHERA BARAT
Authors: Pasongli Hernita , Dirawan Gufran D. , . Suprapta 
Published: March 2024

Kecamatan Jailolo merupakan salah satu wilayah yangÂ memiliki prospek terpenting dalam sektorÂ perikanan tambak di Maluku Utara, karena di Jailolo memiliki potensi sumber daya pantai dan lautnya sangat potensial untuk menghasilkan produk-produk perikanan.Penelitian ini bertujuan(i) Merancang zona yang tepat untuk pengembangan udang Vaname pada aspek kualitas air di Desa Todowongi Kecamatan Jailolo Kabupaten Halmahera Barat.Penelitian ini menggunakan metode survey Hasil penelitian menunjukan bahwa; (i) Karakteristik kesesuaian tambak di Desa Todowongi dikatagorikan sangat sesuai (S1) pada aspek kualitas airÂ (suhu, pH air, kecerahan, Nitrat, Hidrogen sulfide) sedangkan katagori cukup sesuai (S2) pada salinitas dan oksigen terlarut. Untuk katagori kurang sesuai (S3) pada nitrit dan katogori tidak (N) sesuai pada kandungan amoniak; (ii) Sedangkan tingkat kesesuaian tambak berdasarkan karakteristik kualitas air adalah katagori sangat sesuai; (iii) Zona untuk pengembangan udang Vaname di Desa Todowongi adalah sangat sesuai pada semua tambak sehingga dapat dijadikan sentra produksi udang terbesar di Kecamatan Jailolo Kabupaten Halmahera Barat.Â Kata Kunci: Zonasi,kesesuaian tambak, kualitas air
Development of Phytoremediation Module Based on Research Results
Authors: Yulis Putri Ade Rahma , Nafsi Radhiatun , Desti Desti , Suryanti Suryanti , Sari Yelfira 
Published: March 2024

This study aims to develop and examine the validity of module development based on the research outcome on Phytoremediation. This phytoremediation material was one of the topics in the Biotechnology course studied by Biology Education students. The research method used research and development with the ADDIE model, namely analysis, design, development, implementation, and evaluation. However, this research was conducted until the development stage. The data were the percentage of product validity from validation sheets and the responses obtained from validation results by material and media experts. Limited trials were subsequently conducted on students of Biology Education who had taken Biotechnology classes. The data analysis technique used qualitative and quantitative descriptive analysis. The validation results based on the material experts were 79.74% (very valid), while based on the learning experts, it was 97.50% (very valid). Then, the results of small group trials obtained a percentage of 90.70% (very valid). moduleModules development was very valid and feasible to be implemented. This module was expected to raise the students’ effectiveness in attending lectures because the source of teaching materials was more applicable.
In vitro and in silico biopotentials of phytochemical compositions and antistaphylococcal and antipseudomonal activities of volatile compounds of Argania spinosa (L.) seed oil
Authors: Almuhayawi Mohammed S. , Alruhaili Mohammed H. , Gattan Hattan S. , Alharbi Mohanned Talal , Nagshabandi Mohammed K. , Hagagy Nashwa , Almuhayawi Saad M. , Al Jaouni Soad K. , Selim Samy , Mostafa Ehab M. , Elnosary Mohamed E. 
Published: March 2024

Active components in medicinal plants provide unlimited useful and traditional medicines. Antimicrobial activities are found in secondary metabolites in plant extracts such as argan oil. This experimental investigation aims to determine argan oil’s volatile compounds and examine their in vitro antimicrobial properties. In silico simulations, molecular docking, pharmacokinetics, and drug-likeness prediction revealed the processes underlying the in vitro biological possessions. Gas chromatography–mass spectrometry (GC/MS) was used to screen argan oil’s primary components. In silico molecular docking studies were used to investigate the ability of the selected bioactive constituents of argan oil to act effectively against Pseudomonas aeruginosa and Staphylococcus aureus (S. aureus) isolated from infections. The goal was to study their ability to interact with both bacteria’s essential therapeutic target protein. The 21 chemicals in argan oil were identified by GC/MS. Docking results for all compounds with S. aureus and P. aeruginosa protease proteins ranged from −5 to −9.4 kcal/mol and −5.7 to −9.7 kcal/mol, respectively, compared to reference ligands. Our docking result indicates that the 10-octadecenoic acid, methyl ester was the most significant compound with affinity scores of −9.4 and −9.7 kcal/mol for S. aureus and P. aeruginosa proteins, respectively. The minimal bactericidal concentration (MBC) and minimal inhibitory concentration (MIC) of argan oil were 0.7 ± 0.03 and 0.5 ± 0.01 for S. aureus and 0.4 ± 0.01 and 0.3 ± 0.02 for P. aeruginosa, respectively. We confirmed the antimicrobial properties of argan oil that showed significant growth inhibition for S. aureus and P. aeruginosa.
The Fbn1 gene variant governs passive ascending aortic mechanics in the mgΔlpn mouse model of Marfan syndrome when superimposed to perlecan haploinsufficiency
Authors: Tarraf Samar A. , de Souza Rodrigo Barbosa , Herrick Ashley , Pereira Lygia V. , Bellini Chiara 
Published: March 2024

IntroductionAscending thoracic aortic aneurysms arise from pathological tissue remodeling that leads to abnormal wall dilation and increases the risk of fatal dissection/rupture. Large variability in disease manifestations across family members who carry a causative genetic variant for thoracic aortic aneurysms suggests that genetic modifiers may exacerbate clinical outcomes. Decreased perlecan expression in the aorta of mgΔlpn mice with severe Marfan syndrome phenotype advocates for exploring perlecan-encoding Hspg2 as a candidate modifier gene.MethodsTo determine the effect of concurrent Hspg2 and Fbn1 mutations on the progression of thoracic aortopathy, we characterized the microstructure and passive mechanical response of the ascending thoracic aorta in female mice of four genetic backgrounds: wild-type, heterozygous with a mutation in the Fbn1 gene (mgΔlpn), heterozygous with a mutation in the Hspg2 gene (Hspg2+/−), and double mutants carrying both the Fbn1 and Hspg2 variants (dMut).ResultsElastic fiber fragmentation and medial disarray progress from the internal elastic lamina outward as the ascending thoracic aorta dilates in mgΔlpn and dMut mice. Concurrent increase in total collagen content relative to elastin reduces energy storage capacity and cyclic distensibility of aortic tissues from mice that carry the Fbn1 variant. Inherent circumferential tissue stiffening strongly correlates with the severity of aortic dilatation in mgΔlpn and dMut mice. Perlecan haploinsufficiency superimposed to the mgΔlpn mutation curbs the viability of dMut mice, increases the occurrence of aortic enlargement, and reduces the axial stretch in aortic tissues.DiscussionOverall, our findings show that dMut mice are more vulnerable than mgΔlpn mice without an Hspg2 mutation, yet later endpoints and additional structural and functional readouts are needed to identify causative mechanisms.
“We try to give a good life to the children”-refugee parents and ECE professionals experiences of the early childhood education partnership in Norway
Authors: Lund Hilde Hjertager 
Published: March 2024

IntroductionChildren in Europe and Norway grow up in an increasingly culturally diverse society. As of 2022, 20% of children in Norwegian Early Childhood Education (ECE) institutions have a minority background. It is essential for parents and ECE professionals to work together to ensure a good start for these children. The partnership between the ECE institutions and parents is a statutory right and duty, and parents should, on equal terms, participate and influence what happens in the ECE institutions. However, research has shown a wide variation in how ECE professionals create partnerships with minority and refugee parents, and many find working with this group of parents challenging. This article explores the experiences of the interactions and encounters between refugee parents and ECE professionals in a Norwegian ECE setting. The aim is to analyze the tensions in this partnership and provide insights into these encounters, negotiation processes and their experiences.MethodologyThe study is based on semi-structured interviews with twelve refugee parents, interviews with six pedagogical leaders, and one kindergarten manager. Additionally, fieldwork was conducted in one ECE institution to provide contextual depth.ResultsThe data is analyzed thematically using an inductive research design. Through this analysis, three prominent themes emerged: 1) Barriers, 2) “Norwegianness”, and 3) Trust. The findings highlight the importance of trust in children’s care and the ECE institution’s safety. At the same time, refugee parents emphasize education as a key to a promising future in Norway and value the education aspect of ECE institutions as high. Communication and language barriers pose an extra burden or stress for both ECE professionals and refugee parents. “Norwegianness” as a cultural norm within ECE institutions is linked to the values, norms, and cultural capital valid within the ECE institution.DiscussionThe findings are discussed within the theoretical frameworks of cultural capital and power relations and critical pedagogy. The interactions and encounters between refugee parents and ECE professionals show tensions arising from differences in cultural norms and understandings. In summary, this article explores the challenges posed by cultural diversity in ECE institutions and argues for using cultural sensitivity to foster more flexibility in these encounters to enhance inclusion and belonging in ECE institutions.
Case report: A novel splice-site mutation of MTX2 gene caused mandibuloacral dysplasia progeroid syndrome: the first report from China and literature review
Authors: Fu Xiaohui , Chen Shuli , Huang Xiao , Lu Qinghua , Cui Yunfei , Lin Weinan , Yang Qin 
Published: March 2024

BackgroundMandibuloacral dysplasia (MAD) syndrome is a rare genetic disease. Several progeroid syndromes including mandibuloacral dysplasia type A (MADA), mandibuloacral dysplasia type B(MADB), Hutchinson-Gilford progeria (HGPS) and mandibular hypoplasia, deafness, and lipodystrophy syndrome (MDPL) have been reported previously. A novel MAD progeroid syndrome (MADaM) has recently been reported. So far, 7 cases of MADaM diagnosed with molecular diagnostics have been reported in worldwide. In the Chinese population, cases of MAD associated with the MTX2 variant have never been reported.MethodsThe clinical symptoms and the genetic analysis were identified and investigated in patients presented with the disease. In addition, we analyzed and compared 7 MADaM cases reported worldwide and summarized the progeroid syndromes reported in the Chinese population to date.ResultsThe present study reports a case of a novel homozygous mutation c.378 + 1G &gt; A in the MTX2 gene, which has not been previously reported in the literature. Patients present with early onset and severe symptoms and soon after birth are found to have growth retardation. In addition to the progeroid features, skeletal deformities, generalized lipodystrophy reported previously, and other multisystem involvement, e.g. hepatosplenic, renal, and cardiovascular system, this case was also reported to have combined hypogammaglobulinemia. She has since been admitted to the hospital several times for infections. Among 22 previously reported progeroid syndromes, 16/22 were MADA or HGPS caused by LMNA gene mutations, and the homozygous c.1579C &gt; T (p.R527C) mutation may be a hot spot mutation for MAD in the Chinese population. MAD and HGPS mostly present in infancy with skin abnormalities or alopecia, MDPL mostly presents in school age with growth retardation as the first manifestation, and is often combined with an endocrine metabolism disorder after several decades.ConclusionThis is the first case of MAD syndrome caused by mutations in MTX2 gene reported in the Chinese population. MTX2 gene c.378 + 1G &gt; A homozygous mutation has not been previously reported and the report of this patient expands the spectrum of MTX2 mutations. In addition, we summarized the genotypes and clinical characteristics of patients with progeroid syndromes in China.
Long-term changes in vegetation and land use in mountainous areas with heavy snowfalls in northern Japan: an 80-year comparison of vegetation maps
Authors: Shitara Takuto , Kurokawa Hiroko , Oguro Michio , Sasaki Takehiro , Ohashi Haruka , Niiyama Kaoru , Shibata Mitsue , Matsui Tetsuya 
Published: March 2024

Comparison of old and new vegetation maps is an effective way to detect vegetation dynamics. Recent developments in computer technology have made it possible to accurately compare old paper vegetation maps with current digitized vegetation maps to reveal long-term vegetation dynamics. Recently, a 1:50,000 scale vegetation map of the Hakkoda Mountains in northern Japan, located in the ecotone of cool temperate and subalpine forests in northern Japan under an East Asian monsoon climate, from 1930 was discovered. We compared the 1930s vegetation map with the most recent 2010 vegetation map to test the following hypotheses: 1) the occurrence of upward expansion of the upper limit of cool-temperate deciduous forests, and 2) whether designation as a national park in 1936 would have reduced forestry and land use, expanded beech forests, and cool-temperate deciduous forests. To compare vegetation changes, 67 types of vegetation legends for the 1930 and 2010 maps were unified to 21 based on plant species composition. Consequently, vegetation has changed substantially over the past 80 years. 1) In the subalpine zone above 1,000 m, the coniferous forest area decreased by half. In the cool temperate zone below 1,000 m, the area of beech forests increased 1.48 times, and some of them could be shifted upwards, replacing subalpine fir forests in the lower part of the subalpine zone. 2) In areas below 700 m, deciduous oak forests once used as thickets were almost halved. Instead, climax and beech forests expanded. However, we also found that even after the area was declared a national park, oak forests were cleared and converted to commercial forests such as cedar plantations, cattle ranches, and horse pastures in some areas. These results will be useful for future ecosystem and biodiversity research/conservation and will provide baseline information for climate change adaptation policies.
Carbon conduction effect and multi-scenario carbon emission responses of land use patterns transfer: a case study of the Baiyangdian basin in China
Authors: Gao Xing , Zhao Meiran , Zhang Mengmeng , Guo Zhongyuan , Liu Xiao , Yuan Zihua 
Published: March 2024

Carbon pooling and release occur all the time in all corners of the earth, where the land use factor is key to influencing the realization of carbon peaking and neutrality. Land use patterns and carbon emissions change under different scenarios and analyzing the correlation will help formulate scientific land use policies for the future. In this study, through remote sensing data, we investigated the changes in land use patterns and carbon emissions in the Baiyangdian basin in China from 2000 to 2020 and analyzed the carbon conduction effect with the help of a land transfer matrix. The geographical simulation and optimization system-future land use simulation (GeoSOS-FLUS) and Markov models were used to predict the land use changes and carbon emissions under the four different scenarios for the region in 2035. The results indicated that 1) the net land use carbon emissions increased from 52,163.03 × 103 to 260,754.91.28 × 103 t from 2000 to 2020, and the carbon source-sink ratio exhibited a general uptrend; 2) the net carbon emissions due to terrestrial transfers increased over time. The carbon conduction effects due to the transfer of forests, grasslands, water areas, and unused lands to built-up lands also showed a rising trend, albeit the latter two exhibited only small changes; 3) in 2035, the net carbon uptake under the four development scenarios was predicted to be 404,238.04 × 103, 402,009.45 × 103, 404,231.64 × 103, and 404,202.87×103 t, respectively, with all values much higher than that of the study area in 2020. The maximum carbon sink capacity was 817.88 × 103 t under the double-carbon target scenario, and the maximum carbon source emission was 405,033.61 × 103 t under the natural development scenario. The above results provide an essential reference for low carbon-based urban land use regulations for the Baiyangdian basin and other similar projects in the future.
Assessing the performance of five adult mosquito sampling methods for malaria vector surveillance in various ecosystems in Cameroon
Authors: Nwane Philippe , Piameu Michael , Emalio Yannick Niamsi , Ekoko Wolfgang Eyisap , Mandeng Stanislas Elysée , Mbakop Lili Ranaise , Patchoke Salomon , Toto Jean-Claude , Alenou Leo Dilane , Bikoi Elisabeth Ngo , Onguina Hugues , Nvondo Narcisse , Mimpfoundi Remy , Tabue Raymond , Bigoga Jude , Fondjo Etienne , Awono-Ambene Parfait , Etang Josiane 
Published: March 2024

IntroductionMany sampling methods are used for entomological surveillance of vector borne diseases. This paper, evaluated the performance of five methods with regard to various ecosystems encountered in Cameroon. Material and methodsTwo entomological databases generated during two study periods were examined: 2011-2014 in the North Region, and 2018-2019 in the Centre Region. Mosquitoes were collected using the (Human Landing Catches) (HLC) and four alternative methods including Clay Pots (CPs), Pyrethroid Spray Catches (PSCs), Window Exit Traps (WETs) and Centers for Disease Control-Light Traps (CDC-LTs) for which the performance was assessed in this study.ResultsA total of 29 anopheline species were identified from samples collected during the two study periods. All these anopheline species were found in North Region, with 5 species being the most abundant and prévalent, i.e. An. gambiae s.l, An. funestus, An. rufipes, An. paludis and An. pharoensis. In the Centre Region, only five species including An. gambiae s.l, An. funestus, An. coustani, An. ziemanni and An. paludis were recorded. Among these, An. gambiae s.l was the most abundant and prevalent species. Data confirmed HLC as the best in sampling outdoor and indoor mosquitoes in the surveyed HDs. The alternative methods showed variable records regarding the species richness. Based on the number of mosquitoes collected, CP was an alternative to HLC for outdoor collections in Garoua and Pitoa HDs, while WET was an alternative in Mayo Oulo HD. In the Centre Region, CDC-LT was an alternative to HLC for indoor collections in Ekié and Nkolbisson HDs, while PSC proved to be the best alternative in Nkolondom HD. Regarding the species richness WET appeared as an alternative to HLC in sampling outdoor mosquitoes in Garoua and Mayo Oulo HDs, while CP was the best alternative in Pitoa HD. In the Centre Region, CDC-LT was an alternative for outdoor and indoor collections in Nkolbisson HD, and the best alternative for outdoor collections in Ekie HD. Conclusion The current study revealed variable performance of the five tested adult mosquito collection methods across the prospected HDs in North and Centre Regions of Cameroon. Further investigations will be conducted on other collection methods, e.g., aspiration, mosquito electrocuting grid trap, ovitraps and human-baited double net trap.