bluuebunny/crossref_metadata_2025_split huggingface dataset:
Are nanotextures enough to kill cancer cells?
Authors: Webster Thomas J 
Published: April 2024

Are nanotextures enough to kill cancer cells?
Nanotextures on nanoparticles and implants to kill cancer cells in a more targeted manner may just be the key to tackling resistance to traditional cancer drugs. Is our fight against cancer complete? Consider that although for many cancer diagnoses, while people are living longer, the rate of cancer metastasis is still increasing.(1) Further, consider that prostate and some other select cancers remain persistent with only a few new approaches, and even those are not working.(2) In fact, most oncologists only look to the drug industry (a.k.a., Big PHARMA) to develop new drugs to help them. Does anyone believe this is the best we can do? Are chemotherapeutics really the answer? Have drugs worked for eradicating infection (e.g. antibiotic-resistant bacteria) or for treating chronic pain (e.g. opioid addiction)?
Tackling physical inactivity and a sedentary lifestyle: Two distinct approaches
Authors: Dionne Isabelle J 
Published: April 2024

Tackling physical inactivity and a sedentary lifestyle: Two distinct approaches
Being physically inactive and sedentary are two distinct issues that affect older adults. However, each problem necessitates a unique set of solutions; Professor Isabelle J. Dionne from the Université de Sherbrooke tells us more. Sedentary behavior and the inability to attain physical activity recommendations are two different concepts, largely confounded. In turn, there is a misconception of their respective impact on healthy aging and how they can be counteracted. As a result, physical activity and clinical guidelines may miss the target.
Investigating lung cancer using genetically engineered mouse models (GEMMS)
Authors: Murphy Daniel J 
Published: April 2024

Investigating lung cancer using genetically engineered mouse models (GEMMS)
Daniel J. Murphy, Professor of Lung Cancer & Mesothelioma at the University of Glasgow, School of Cancer Sciences, discusses opportunities for improving cancer research and care through the use of genetically engineered mouse models. Despite changes in smoking habits, cancers of the lung remain the most lethal types of cancer in the UK and worldwide. In the UK, lung cancer accounts for over 20% of all deaths from cancer, claiming almost 35,000 victims annually (2017-2019 CRUK Lung Cancer Statistics). Until very recently, the vast majority of lung cancers were diagnosed at a late stage – meaning the cancers were very well established and at their most aggressive. Few of these cases respond effectively to treatment; when they do, responses are often short-lived.
Permafrost grown: The heterogeneity of permafrost conditions
Authors: Ward Jones Melissa 
Published: April 2024

Permafrost grown: The heterogeneity of permafrost conditions
Melissa Ward Jones, from the University of Alaska Fairbanks, explains the heterogeneity of permafrost conditions and how it can impact agriculture. One farmer describes clearing land and letting it thaw before cultivation to increase the soil’s temperature; another describes needing to allow the field to dry out after land clearing, as it is too wet to access and cultivate for a few seasons. The third describes land sinking and waterlogging that developed in a portion of their field a few years after clearing. Each farmer is describing a response to thawing permafrost.
The future of sustainable electrified catalyst recycling
Authors: Dominguez Benetton Xochitl 
Published: April 2024

The future of sustainable electrified catalyst recycling
Xochitl Dominguez Benetton, Senior Scientist & Project Coordinator at the Flemish Institute for Technological Research (VITO) and the FIREFLY consortium, explore competitiveness and sovereignty through sustainable electrified catalyst recycling. In the heart of today’s industrialised economies, the chemical industry stands as a cornerstone, particularly in the European Union (EU), where it ranks as the second largest globally, boasting sales of over €500 billion – a 38% increase since 2000. The path to maintaining this industry’s vitality lies in sustainable practices: optimising energy use, reducing hazardous emissions, and increasing recycled material use. Catalysts are the silent heroes of this industry, with 90% of chemical processes depending on them. Essentially, without catalysts, the chemical industry’s backbone would crumble. They are crucial for more efficient reactions, reducing energy use and emissions, and thereby fostering a cleaner, more sustainable economy. Yet, the reliance on metals, often categorised as critical raw materials due to high economic value and supply risks, underscores a vulnerability in sovereignty and competitiveness, mainly when sourced from geopolitically unstable regions.
Vaccine non-responders and severe adverse events
Authors: Klaus Eyer 
Published: April 2024

Vaccine non-responders and severe adverse events
Eyer Klaus, an Associate Professor at Aarhus University’s Department of Biomedicine, explores the causes, impact, and potential resolutions of vaccine non-responsiveness and severe side effects. Vaccination has had a tremendous net positive effect on individual and public health and remains a crucial and cost-effective preventive pharmaceutical intervention. While most vaccine recipients develop protective immunity, some individuals do not, and rare severe side effects may occur. Both occurrences represent key problems in vaccination, not only at the individual level but also beyond. This discourse delves into the complexities surrounding these issues and highlights interconnected challenges alongside prospective resolutions from a basic researcher’s perspective.
The future of dentistry: Exploring the latest advancements in dental imaging
Authors: Zhu Yihua 
Published: April 2024

The future of dentistry: Exploring the latest advancements in dental imaging
Advancements in dental imaging over the past two decades have been remarkable, such as cross-polarization OCT; Yihua Zhu and his team at the University of California, San Francisco, have been investigating different diagnostic imaging methods. Yihua Zhu and his team at the University of California have extensively explored innovative imaging techniques, comparing them with conventional methods. Their focus has been on enhancing short wavelength infrared (SWIR) technologies, developing a dual probe for investigating dental cavities, and, more recently, introducing a novel SWIR multispectral transillumination and reflective imaging method. This research signifies a significant leap in providing a highly sensitive and efficient approach to visualizing dental cavities, tracking tooth decay progression, and assessing prevalent dental issues.
Navigating health autonomy through self-care
Authors: El-Osta Austen 
Published: April 2024

Navigating health autonomy through self-care
Interest in self-care has exploded in recent years, highlighting its crucial role in shaping future healthcare systems. Imperial SCARU’s Dr Austen El-Osta discusses emerging trends, research priorities and self-care policy landscapes, advocating for a global movement towrds accessible and empowered health management. The last decade has witnessed a paradigm shift in healthcare, with self-care emerging as a key component in managing health and wellbeing. The collective insights from the World Health Organization (WHO), Imperial College London Self-Care Academic Research Unit (SCARU) and the recent São Paulo Declaration highlight a global movement towards integrating self-care into the fabric of healthcare systems.
Engineered endosymbionts as novel cancer therapeutics
Authors: Kulkarni Satyajit Hari , Contag Christopher H 
Published: April 2024

Engineered endosymbionts as novel cancer therapeutics
Satyajit Hari Kulkarni and Christopher H. Contag from the Institute for Quantitative Health Science and Engineering focus on engineered endosymbionts, which they argue is a paradigm shift in anticancer bacteriotherapy toward killing tumors from the inside out. Cancer is a genetic disease that can be initiated and/or exacerbated by environmental factors leading to metabolic changes in cells that result in uncontrolled growth. Key genetic changes in cancer cells include altered expression of cancer-promoting genes (oncogenes) or tumor suppressor genes. These genes encode proteins that promote cellular proliferation by interacting with DNA (transcription factors), nuclear proteins that control cell division at the level of the cell cycle, or proteins that prolong cell survival by avoiding programmed cell death (apoptosis).
Violent extremism: The journey in and the pathway out
Authors: Bøås Morten 
Published: April 2024

Violent extremism: The journey in and the pathway out
Understanding and addressing violent extremism goes beyond just ideology. Morten Bøås of the Norwegian Institute of International Affairs suggests that looking at the underlying reasons and addressing its root cause might be crucial to finding solutions. Defining violent extremism is like grabbing slippery soap. Most of us have ideas about what violent extremism is, what type of acts of violence qualify, and what kinds of ideologies and belief systems that we would say promote it. The challenge, however, is that the definition of violent extremism is almost exclusively subjective. What one person deems as violent extremism may be perfectly justifiable for another.
Innovative climate research for guiding policy-making
Authors: Koundouri Phoebe 
Published: April 2024

Innovative climate research for guiding policy-making
Professor Phoebe Koundouri leads AE4RIA and UN SDSN Global Climate Hub, participating in innovative climate research impact projects. In the face of the climate crisis, a challenge that intertwines ecological balance with socio-economic stability, initiatives like the Alliance of Excellence for Research and Innovation on Aephoria (AE4RIA) and the UN SDSN Global Climate Hub (GCH) are instrumental. These organizations foster innovative research and actionable solutions to navigate the complexities of climate change and drive global efforts towards a sustainable and resilient future, and co-ordinate a science-based, holistic response to the climate crisis, supporting not only environmental integrity but also socio-economic resilience. As we navigate the complexities of a warming planet, initiatives like AE4RIA and GCH are crucial, harnessing collaborative expertise to drive the global agenda towards a sustainable and equitable future for all.
Enhance expertise in European research infrastructures
Authors: Lavitrano Marialuisa 
Published: April 2024

Enhance expertise in European research infrastructures
Marialuisa Lavitrano, Full Professor at University Milano Bicocca, explores the need for a European School for the Management of Research Infrastructure to enhance expertise in European research infrastructure management. European Research Infrastructures (RI) are complex organisations that offer the research communities access to cutting-edge resources, data, and services to conduct research and foster innovation in their fields. RIs include major scientific equipment (or sets of instruments), knowledge-based resources such as collections, archives, and scientific data, e-infrastructures, such as data and computing systems and communication networks, and other tools and services essential to achieving excellence in research and innovation. RI span the whole spectrum of knowledge from social sciences to astrophysics, including environmental sciences and large-scale infrastructures.
Unlocking the power of energy efficiency: A multi-benefit approach with the referee tool
Authors: Faberi Stefano , Kerneïs Klervi 
Published: April 2024

Unlocking the power of energy efficiency: A multi-benefit approach with the referee tool
Energy efficiency is a cornerstone of the European Green Deal and the European Union’s (EU) pathway toward carbon neutrality. With implementation efforts underway across the Continent, the Referee tool stands ready to support decision-makers and stakeholders in their energy efficiency planning, embracing a multi-benefits approach. Energy efficiency has long been championed as a vital tool in the fight against climate change. According to the 2022 IPCC report, energy efficiency in the industrial, ground transportation, and building sectors is the best way to reduce greenhouse gas emissions. For instance, significant energy efficiency improvements in the building sector (e.g. more energy-efficient heating systems, better insulation) could reduce the energy demand of the residential building stock in the EU by 19.4% in 2030 and by 43% in 2050 compared to 2018 levels.
Why greener pharmaceutical manufacturing is vital for the industry and our health
Authors: McElhone Deborah , Cassey Barrie 
Published: April 2024

Why greener pharmaceutical manufacturing is vital for the industry and our health
Determined to tackle the carbon footprint of medicine, CPI’s Medicines Manufacturing Innovation Centre is addressing key sustainability issues in pharmaceutical manufacturing. Climate change is the most significant health threat to modern society (1), and the pharmaceutical industry faces sustainability challenges like every other industry. Even though much of the pharmaceutical industry’s output saves and significantly improves the quality of life for billions of people, this cannot come at any cost to the planet. Recently, health agencies, such as the NHS, have set ambitious net zero targets, and as medicine accounts for 25% of NHS carbon emissions, the pharmaceutical industry has a crucial role to play in tackling this threat. (2)
Tuneable phononic crystals and topological acoustics
Authors: Banerjee Sourav 
Published: April 2024

Tuneable phononic crystals and topological acoustics
Sourav Banerjee, Professor from the University of South Carolina, navigates the field of tuneable phononic crystals and topological acoustics. Acoustics, an age-old field of study, has recently revealed new physics with new degrees of freedom of wave propagation. These new findings are invaluable for information processing using acoustic modality. Information processing using acoustics is called acoustic computing. Computing Boolean algebra, which has already been demonstrated, could pave the pathways even for quantum computing using acoustics. Not in the very distant future, the recently discovered quantum and topological behavior of acoustics could be an integral part of computing modalities.
Local exposure to asylum seekers promotes a more positive attitude toward ethnic diversity
Authors: Suetens Sigrid 
Published: April 2024

Local exposure to asylum seekers promotes a more positive attitude toward ethnic diversity
Sigrid Suetens, Professor from Tilburg University School of Economics and Management, shows that local exposure to asylum seekers promotes a more positive attitude toward ethnic diversity. People who live near a refugee centre tend to develop a more positive attitude toward asylum seekers than those who live further away. They are also less likely to support anti-immigration parties. This is the conclusion of research conducted by economist Sigrid Suetens and her team. The study suggests this positive attitude results from contact between local residents and refugees.
STUDENT'S PERCEPTION ON USING GOOGLE CLASSROOM IN DISTANCE LEARNING
Authors: Rahmiati  , Saiful  , Sujariati  
Published: April 2024

This research focused on the students perception on using Google Classroom in distance learning. This research used a mixed methods. The subject of this research was the 30 students taken from class XI MIA 4 (Natural Science). The data of the students perception on using Google Classroom in distance learning were obtained from the result of the questionnaire and interview. The result of this research indicated a positive response from the students. The findings showed that of the 20 items on the questionnaire, strongly agree and agree have the highest percentage of positive statements. Strongly agree had a percentage of 3,3-30% and agree had a percentage of 3,3-60%. Meanwhile, interview results show that using Google Classroom makes it easier for students in the distance learning process, and the challenges faced by students were not understanding the material and network connections.
El Uso del Andamiaje Instruccional con la Respuesta Física Total (RTP) para Mejorar las Habilidades de la Comunicación Oral en Contextos Virtuales
Authors: Heath Kate Elizabeth 
Published: April 2024

Este proyecto de investigación-acción estudió el efecto de proveer comentariointeraccional por el uso de gestos basados en la teoría de la Respuesta Física Total (RTP)para apoyar las respuestas habladas de los estudiantes en un aula virtual. Fue creado pararesponder a dos preguntas: ¿cómo mejora el andamiaje instruccional con la RTP las
habilidades de la comunicación de los estudiantes? ¿Se puede usar la RTP para apoyar elaprendizaje y aumentar la autonomía estudiantil donde confrontan dificultades? Estainvestigación empezó después de notar que muchas de los estudiantes simplementerepetían al profesor cuando se equivocaban sin mejorar su pronunciación o aplicar lasintaxis o el lexis apropiado cuando respondían. Para proveer comentario y solicitar unasauto-correcciones de los estudiantes, los gestos fueros incorporados como una manera deapoyar sus respuestas. Después de recordar cinco clases de 25 minutos con cuatroestudiantes y transcribirlas, fue concluido que el andamiaje instruccional con la RTPsolicitó correcciones, mejoró las habilidades de la comunicación oral, y aumentó laautonomía de los estudiantes.
¿Es la adquisición de múltiples lenguas un reto?
Authors: Ortega Duran Mireia 
Published: April 2024

El interés por el multilingüismo y la adquisición multilingüe ha aumentadoconsiderablemente en las últimas décadas, lo que refleja la realidad a nivel mundial. Elpresente artículo ofrece una visión general de la investigación sobre la adquisiciónmultilingüe, con un enfoque en factores psicolingüísticos destacando las característicasúnicas de los aprendices multilingües en comparación con los monolingües que adquierensu primera lengua extranjera. También se describen los complejos procesos involucradosen la adquisición multilingüe, así como los diferentes modelos que explican dicha
complejidad. El creciente contacto entre las diferentes lenguas en un mundo globalizadomotiva un cambio de paradigma. De este modo, se ha puesto de manifiesto que losmodelos de adquisición del lenguaje tienen que explicar los procesos que inevitablementeocurren debido a las interacciones entre las lenguas que conforman el repertoriolingüístico de los aprendices. Estos nuevos paradigmas que han surgido en la investigaciónde segundas lenguas podrían también ser incorporados en la enseñanza de lenguasextranjeras, lo que podría ayudar a los aprendices en su proceso de adquisición.
J. M. Coetzee´s In the Heart of the Country: Magda’s Search for a New Language
Authors: Álvarez Sánchez Patricia 
Published: April 2024

Irigaray has explored and analysed how both psychoanalysis and philosophy have managed to exclude women from a meaningful existence as independent subjects. In her work Speculum of the Other Woman, she demonstrates how Western civilisation has been articulated according to a masculine ideology that silences women in their discourse. She also emphasizes that women need to occupy language in order to create a separate identity. In this article, I will link her feminist ideas on language with Magda, the protagonist of J.M. Coetzee’s In the Heart of the Country, a novel that was published in the middle of the second-wave feminism. I will analyse how Magda tries to reinvent her identity outside the patriarchal world she inhabits and discover a new language in order to transcend the masculine imaginary and its boundaries. I will also explore her remarkable alliance with other female writers: Perkins Gilman, Plath and, above all, Woolf.
Interdisciplinary collaborative approaches in Higher Education: Open Educational Resources for Subject and Language Lecturers
Authors: Piquer-Píriz Ana María , Morgado Margarida , Zverinova Jana 
Published: April 2024

The so-called ‘internationalisation at home’ (Beelen and Jones 64) of Higher Education Institutions (HEIs), and the need to prepare students for globalised working environments, among other factors, are powerful drivers for change in how we teach at the tertiary level. In the framework of an EU-funded innovation project being developed internationally, called Interdisciplinary Collaborative Approaches to Learning and Teaching (INCOLLAB), this article proposes to look at two aspects, namely interdisciplinary approaches through CLIL, the integrated learning of content and language, and the concomitant collaboration among content and language lecturers to plan and design innovative customisable teaching materials as Open Educational Resources (OERs) that can be adapted and used in similar educational contexts. We describe two specific proposals of OERs on the topic of ‘Autonomy Support’ both as part of the subject of ‘Developmental Psychology’ as well as a transversal skill and analyse the results of their implementation in three real contexts.
Dicotomía “Libertad constitucional vs. Censura sociocultural” durante la primera mitad del siglo XX en España en la novela Como el viento de otoño de Teresa Cameselle
Authors: TERCERO DOÑATE MARÍA TERESA 
Published: April 2024

Resumen
La Segunda República española simboliza un punto de inflexión para la lucha de la liberación de la mujer en el siglo XX. No obstante, el avance histórico hacia una modernización constitucional de género no erradica las bases socialmente arraigadas del modelo decimonónico femenino del “ángel del hogar”. La novela Como el viento de otoño, de Teresa Cameselle, retrata una España que respalda la igualdad de sexos y en la que, a su vez, perdura una cultura y un sistema patriarcal que censura la práctica de estas nuevas libertades. El propósito principal de mi estudio es analizar la recreación literaria de la dicotomía “Libertad constitucional vs. Censura sociocultural” presente en el siglo XX mediante los personajes femeninos de la novela. A su vez, a través de dicha investigación llevaré a cabo una reflexión sobre la revisión de la memoria histórica en España con una mirada de género.
Analysis of Financial and Non-Financial Performance of Public Sector Organizations
Authors: Muchran Muchriana , Idrawahyuni Retno Pinasti Putri 
Published: April 2024

Purpose – This study aims to measure the implementation of the work program of Makassar Hajj Hospital, both from financial and non-financial aspects in 2019-2021
Design/methodology/approach – Using a Balanced Scorecard approach to analyze performance, focusing on financial aspects such as economics, efficiency, and effectiveness, as well as non-financial aspects such as customer satisfaction, internal business processes, and growth and learning
Findings – Balanced Scorecard that has 4 perspectives
Originality – This thesis introduces financial and non-financial aspects of the Balanced Scorecard approach
Keywords: Financial Performance, Non-financial Performance, Balanced Scorecard
Paper Type Research Result