bluuebunny/crossref_metadata_2025_split huggingface dataset:
PKC‐ε‐dependent cytosol‐to‐membrane translocation of pendrin in rat thyroid PC Cl3 cells
Authors: Muscella A. , Marsigliante S. , Verri T. , Urso L. , Dimitri C. , Bottà G. , Paulmichl M. , Beck‐Peccoz P. , Fugazzola L. , Storelli C. 
Published: May 2008

AbstractWe studied the expression and the hormonal regulation of the PDS gene product, pendrin, which is, in thyrocytes, responsible for the iodide transport out of the cell. We show that PC Cl3 cells, a fully differentiated thyroid cell line, grown without TSH and insulin, express very low level of PDS mRNA; such expression is greatly increased after stimulation with insulin or TSH. 125I pre‐loaded cells showed an 125I efflux accelerated in chloride‐containing buffer with respect to chloride‐free buffer, suggesting that this efflux is chloride dependent. By immunoblotting, pendrin was found in agonists‐stimulated cells, whereas it was barely detectable in un‐stimulated cells. An increase in both PDS mRNA and protein was also obtained using phorbol ester PMA, or using 8‐Br‐cAMP and forskolin. Stimulation with insulin (1 µg/ml; 0–40 min) provoked the cytosol‐to‐membrane translocation of pendrin and a decrease of intracellular I− content in 125I pre‐loaded cells. Insulin‐ or PMA‐treated cells also showed a cytosol‐to‐membrane translocation of PKC‐δ and ‐ε. Inhibition of both PKC‐δ and ‐ε activities by GF109203X blocked pendrin translocation, whilst the inhibition of PKA did not. The selective inhibition of PKC‐δ by rottlerin did not affect the insulin‐provoked translocation of pendrin whilst it was inhibited by a PKC‐ε translocation inhibitor peptide and also by PKC‐ε downregulation using the small interfering RNA, thus indicating that such translocation was due to PKC‐ε activity. In conclusion, our study demonstrates that, in PC Cl3 cells, pendrin expression and localisation are regulated by insulin and influenced by a PKC‐ε‐dependent intracellular pathway. J. Cell. Physiol. 217: 103–112, 2008. © 2008 Wiley‐Liss, Inc.
Inhibition of 5‐HT1A receptor‐dependent cell survival by cAMP/protein kinase A: Role of protein phosphatase 2A and Bax
Authors: Hsiung Shu‐chi , Tin Adrianne , Tamir Hadassah , Franke Thomas F. , Liu Kuo‐peing 
Published: May 2008

AbstractSerotonergic 5‐HT1A receptor signaling leading to nuclear factor‐κB (NF‐κB) activation appears to be critical for cell survival. Adenylyl cyclase and protein kinase A (AC/PKA) are effectors of the 5‐HT1A receptor that are inhibited by Gαi subunits. Conversely, Gβγi subunits downstream from the 5‐HT1A receptor participate in the activation of extracellular signal‐regulated kinases (ERK1/2), phosphatidylinositol 3‐kinase (PI3K), Akt, and NF‐κB. To model the contribution of pro‐ and antiapoptotic signaling cascades downstream of activated 5‐HT1A receptor in cell survival, Chinese hamster ovarian (CHO) cells were employed that exogenously overexpress 5‐HT1A receptors. Stimulation with the 5‐HT1A receptor agonist 8‐OH‐DPAT and pharmacological agonists of AC induced PKA and protein phosphatase 2A (PP2A) activity, which in turn inhibited: Akt activity, IκBα degradation, nuclear translocation of NF‐κB, and expression of X‐linked inhibitor of apoptosis protein (XIAP/BIRC4). Pharmacological inhibition of PP2A with calyculin A potentiated Akt activity while attenuating ERK1/2 signaling via increased inhibitory phosphorylation of Raf (pSer259). In contrast, increased cAMP levels enhanced Bax translocation to the mitochondria, resulting in the release of cytochrome c, caspase‐3 activation, and apoptosis induction. Our data suggest a central role of cAMP/PKA‐dependent PP2A in shifting the homeostasis of intracellular signaling downstream of activated 5‐HT1A receptor toward cell death in biological systems linked to neuropsychiatric disorders. © 2008 Wiley‐Liss, Inc.
Effect of transferrin on hypomyelination induced by iron deficiency
Authors: Badaracco M. E. , Ortiz E. H. , Soto E. F. , Connor J. , Pasquini J. M. 
Published: May 2008

AbstractWe have used a model of iron deficiency in the rat to analyze the effects of a disruption in iron availability on oligodendroglial cell (OLGc) maturation and myelinogenesis and to explore the possible beneficial influence of an intracranial injection (ICI) of apotransferrin (aTf) at 3 days of age on this process. Studies carried out on postnatal days 17 and 24 showed that iron deficiency produced a decrease in myelin proteins and lipids at 24 days of age. Immunohistochemistry showed that in untreated iron‐deficient (ID) rats, the immunoreactivity of anti–adenomatous polyposis coli (APC) and anti‐MBP antibodies decreased markedly with reference to normal controls, whereas in ID rats treated with an ICI of aTf, the immunoreactivity of these markers increased. A similar situation occurred with the immunoreactivity of H‐ferritin. In primary OLGc cultures from ID rats, there was a high number of cells positive to the antibody against the polysialylated form of the cell surface glycoprotein NCAM (PSA‐NCAM) compared with in OLGc cultures prepared from normal controls or from ID animals treated with aTf. The number of MBP+ cells in cultures from ID rats increased after treatment with aTf. The presence of lipid rafts evaluated with a specific anti–protein prion cellular (PrPc) antibody showed a smaller number of PrPc‐positive structures in ID rat cultures. Treatment of the ID animals with a single ICI of aTf stimulated myelination, producing a significant correction in the different biochemical parameters affected by ID. © 2008 Wiley‐Liss, Inc.
HLA‐class I expression in gastric cancer
Authors: Ishigami Sumiya , Natsugoe Shoji , Nakajo Akihiro , Arigami Takaaki , Kitazono Masaki , Okumura Hiroshi , Matsumoto Masataka , Uchikado Yasuto , Setoyama Tetsuro , Sasaki Ken , Aikou Takashi 
Published: May 2008

AbstractPurposeWe investigated the clinical impact of HLA‐class I tumor cells in gastric cancer.Materials and MethodsHLA‐class I expression was immunohistochemically evaluated in specimens from 141 gastric cancer patients. The correlation between HLA‐class I expression and clinical factors was analyzed.ResultsHLA‐class I was identified in 96 (68.1%) gastric carcinomas. The loss of HLA‐class I significantly correlated with the depth of invasion (P < 0.01), nodal involvement (P < 0.05) and tumor histology (P < 0.01). According to the positivity of HLA‐class I, shallow depth and the absence of nodal metastasis increased. HLA‐class I expression was a significant prognostic factor in gastric cancer (P < 0.02); however, HLA‐class I was not an independent prognostic factor by multivariate analysis.ConclusionsOur data may suggest that loss of HLA‐class I in gastric cancer did not directly reflect immunological escape from tumor antigen‐specific cytotoxic T lymphocytes, unlike in other cancers. J. Surg. Oncol. 2008;97:605–608. © 2008 Wiley‐Liss, Inc.
Prospective trial of intensive decongestive physiotherapy for upper extremity lymphedema
Authors: Karadibak Didem , Yavuzsen Tugba , Saydam Serdar 
Published: May 2008

AbstractBackgroundThe aim of this study was to evaluate the effects of kinesiophobia, quality of life, and home exercise programs on women with upper extremity lymphedema.MethodsA total of 62 women with lymphedema after breast cancer treatments were provided a protocol of complete decongestive therapy (CDT). This protocol involved manual lymphatic drainage (MLD), compression garments, skin care, and remedial exercises. The women were taken to a 12‐week therapy program once per day, 3 days per week. A home program, consisting of compression bandage exercises, skin care and walking was recommended. Absolute volume and percentage of volume of the lymphedema were compared before and after treatment. The kinesiophobia, quality of life, and home‐based program were assessed before and after physiotherapy.ResultsStrong correlations were found between the severity of edema and fear of movement. There was a significant negative relationship among the fear of movement, quality of life, and home‐based exercises program. Mean initial lymphedema volume was 925 ml, and the percentage of lymphedema was 47.1%. After decongestive physiotherapy, the lymphedema volume and percentage were 510 ml and 21.3% (P < 0.05), respectively. There was also a trend toward improvement in general well‐being (P < 0.05).ConclusionIn upper extremity lymphedema, the use of complex physiotherapy programs (CDP) can decrease edema and fear of activity, and increase the quality of life. J. Surg. Oncol. 2008;97:572–577. © 2008 Wiley‐Liss, Inc.
Sonographic lesion size of ductal carcinoma in situ as a preoperative predictor for the presence of an invasive focus
Authors: Lee Jong Won , Han Wonshik , Ko Eunyoung , Cho Jihyoung , Kim Eun‐Kyu , Jung So‐Youn , Cho Nariya , Moon Woo Kyung , Park In‐Ae , Noh Dong‐Young 
Published: May 2008

AbstractBackground and ObjectivesTo investigate the preoperative factors associated with upstage to invasive cancer in patients with core needle biopsy (CNB) diagnosis of ductal carcinoma in situ (DCIS) by ultrasound guidance alone.MethodsBetween 2000 and 2007, 201 patients with DCIS diagnosed at 11‐ or 14‐gauge CNB by ultrasound guidance alone were examined. Preoperative factors were all analyzed to correlate with the presence of invasive cancer after definitive resection. The Pearson chi‐square test and stratified analysis with the Mantel‐Haenszel chi‐squire test were used to assess the association between the preoperative factors and upstage to invasive cancer.ResultsCompared with the overall underestimation rate (84 of 201, 41.8%), 47 (60.3%) of 78 patients with abnormal breast palpation, 46 (55.4%) of 83 patients with mammographic finding of a mass lesion, and 38 (67.9%) of 56 patients with a sonographic lesion size >20 mm had invasive cancer components on the final pathology review (Odds ratio [OR] = 2.45; P = 0.04, OR = 3.66; P = 0.002, and OR = 4.13; P = 0.002 respectively).ConclusionA sonographic lesion size >20 mm can be used as another guideline for surgeons to consider sentinel lymph node biopsy in patients with DCIS diagnosed by a sonographically guided CNB. J. Surg. Oncol. 2008;98:15–20. © 2008 Wiley‐Liss, Inc.
A note on optimal pricing for finite capacity queueing systems with multiple customer classes
Authors: Ziya Serhan , Ayhan Hayriye , Foley Robert D. 
Published: May 2008

AbstractThis article investigates optimal static prices for a finite capacity queueing system serving customers from different classes. We first show that the original multi‐class formulation in which the price for each class is a decision variable can be reformulated as a single dimensional problem with the total load as the decision variable. Using this alternative formulation, we prove an upper bound for the optimal arrival rates for a fairly large class of queueing systems and provide sufficient conditions that ensure the existence of a unique optimal arrival rate vector. We show that these conditions hold for M/M/1/m and M/G/s/s systems and prove structural results on the relationships between the optimal arrival rates and system capacity. © 2008 Wiley Periodicals, Inc. Naval Research Logistics, 2008
Metabolic profiling of transgenic adenocarcinoma of mouse prostate (TRAMP) Tissue by 1H‐NMR analysis: evidence for unusual phospholipid metabolism
Authors: Teichert Friederike , Verschoyle Richard D. , Greaves Peter , Edwards Richard E. , Teahan Orla , Jones Donald J.L. , Wilson Ian D. , Farmer Peter B. , Steward William P. , Gant Timothy W. , Gescher Andreas J. , Keun Hector C. 
Published: May 2008

AbstractBACKGROUNDThe TRansgenic Adenocarcinoma of the Mouse Prostate (TRAMP) mouse model has frequently been used in preclinical studies with chemotherapeutic/chemopreventive rationales. Here the hypothesis was tested using 1H‐NMR‐based metabolic profiling that the TRAMP tumor metabolic phenotype resembles that reported for human prostate cancer.METHODSAqueous extracts or intact tissues of normal prostate from 8‐ (“young”) or 28‐(“old”) week‐old C57BL/6J wild‐type mice or of prostate tumor from age‐matched TRAMP mice were analyzed by 1H‐NMR. Results were compared with immunohistochemical findings. Expression of choline kinase was studied at the protein and mRNA levels.RESULTSIn young TRAMP mice presenting with zonal hyperplasia, the ratio of glycerophosphocholine (GPC) to phosphocholine (PC) was 22% below that in wild‐type mice (P < 0.05). In old TRAMP mice with well‐defined malignancy, reduced tumor levels of citrate (49%), choline (33%), PC (57%), GPC (66%), and glycerophosphoinositol (61%) were observed relative to normal prostate (P < 0.05). Hierarchical cluster analysis of metabolite levels distinguished between normal and malignant tissue in old but not young mice. While the reduction in tissue citrate resembles human prostate cancer, low levels of choline species in TRAMP tumors suggest atypical phospholipid metabolism as compared to human prostate cancer. TRAMP tumor and normal prostate tissues did not differ in expression of choline kinase, which is overexpressed in human prostate cancer.CONCLUSIONAlthough prostate cancer in TRAMP mice shares some metabolic features with that in humans, it differs with respect to choline phospholipid metabolism, which could impact upon the interpretation of results from biomarker or chemotherapy/chemoprevention studies. Prostate 68:1035–1047, 2008. © 2008 Wiley‐Liss, Inc.
Diabetes mellitus and prostate cancer risk
Authors: Pierce Brandon L. , Plymate Stephen , Ostrander Elaine A. , Stanford Janet L. 
Published: May 2008

AbstractBACKGROUNDEpidemiological evidence suggests that diabetes mellitus (DM) is associated with a decrease in risk for prostate cancer (PCa). The objective of this study was to examine the association between PCa risk and several characteristics of DM (duration, age at diagnosis, treatment) in data from two population‐based, case‐control studies of PCa.METHODSPCa cases (n = 1,752), and controls (n = 1,644) were residents of King County, Washington identified using the Surveillance, Epidemiology, and End Results Seattle‐Puget Sound cancer registry and random digit dialing, respectively. The majority of PCa patients had localized stage disease (78%). Using self‐reported on DM, logistic regression was used to calculate odds ratios (OR) and 95% confidence intervals (95% CI) for associations between DM characteristics and PCa risk.RESULTSAfter adjustment for confounding factors, DM status was not significantly associated with PCa risk (OR = 0.98; 95% CI = 0.76–1.27). However, early‐onset DM (diagnosed before age 30) showed a significant inverse association with PCa risk (OR = 0.27; 95% CI = 0.07–0.97). Time since DM diagnosis (median = 6 years) and DM treatment types (i.e., diet changes, oral medications, and insulin) did not show significant associations with PCa risk.CONCLUSIONSThese data suggest that DM is not associated with PCa risk; however, early‐onset DM, possibly reflecting insulin dependent DM (type 1), may be an important component of the previously reported inverse association between DM on PCa risk, but these findings are based on a small number of observations and require further investigation. Prostate 68: 1126–1132, 2008. Published 2008 Wiley‐Liss, Inc.
Insulin‐like growth factor binding protein‐3 (IGFBP‐3) in the prostate and in prostate cancer: Local production, distribution and secretion pattern indicate a role in stromal‐epithelial interaction
Authors: Massoner Petra , Haag Petra , Seifarth Christof , Jurgeit Andreas , Rogatsch Hermann , Doppler Wolfgang , Bartsch Georg , Klocker Helmut 
Published: May 2008

AbstractBackgroundInsulin‐like growth factor binding protein 3 (IGFBP‐3) exerts inhibitory and proapoptotic effects on prostate cancer cells. Serum levels of IGFBP‐3 were found to be associated with the risk of prostate cancer, but the data are still inconclusive. We present a detailed analysis of the expression and localization of IGFBP‐3 in the prostate and a comparison with its expression pattern in tumors.MethodsExpression and localization of IGFBP‐3 were analyzed in cellular models and tissue by real‐time RT‐PCR, ELISA, immunohistochemistry, and immunofluorescence.ResultsAll cell types of a panel of benign epithelial, stromal and tumor prostate cells expressed IGFBP‐3. Significantly higher expression levels were registered in stromal cells. TGF‐β stimulation boosted IGFBP‐3 levels 60‐fold in stromal cells. The pattern of expression was confirmed in microdissected tissue samples. Protein levels measured by ELISA paralleled the mRNA levels and more than 80% of IGFBP‐3 was secreted. On tissue immunostaining, IGFBP‐3 was found to be mainly located in the epithelium. The pattern suggested secretion of IGFBP‐3, which was confirmed in prostate tissue cultured ex vivo and the ejaculate of vasectomized men. IGFBP‐3 levels were increased in primary tumors but did not differ from benign epithelium in metastases and local recurrent tumors.ConclusionsWe registered a significant local production of IGFBP‐3 in the prostate, which may well override the effect of protein entering from blood. The stroma—particularly reactivated stroma—is the main source of IGFBP‐3 in the prostate, suggesting that this peptide acts as a mediator of stromal‐epithelial interactions. Prostate 68: 1165–1178, 2008. © 2008 Wiley‐Liss, Inc.
First‐principles study of the electronic structures and absorption spectra for the PbMoO4 crystal with lead vacancy
Authors: Chen Jianyu , Liu Tingyu , Cao Dunhua , Zhao Guangjun 
Published: May 2008

AbstractThe electronic structures and absorption spectra for the perfect PbMoO4 crystal and the crystal containing lead vacancy $ {\rm V}^{2-}_{\rm Pb} $ with lattice structure optimized are calculated using density functional theory code CASTEP. The calculated absorption spectra of the PbMoO4 crystal containing $ {\rm V}^{2-}_{\rm Pb} $ exhibit three absorption bands peaking at 2.0 eV (620 nm), 3.0 eV (413 nm) and 3.3 eV (375 nm), which are in good agreement with experimental values. The theory predicts that the 390 nm, 430 nm and 580 nm absorption bands are related to the existence of $ {\rm V}^{2-}_{\rm Pb} $ in the PbMoO4 crystal. (© 2008 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
NiII‐CdII Heterometallic Coordination Compounds Constructed from Metal‐Containing N, N′‐Rodlike Building Block [Ni(4′‐(3‐pyridyl)‐2,2′:6′,2″‐terpyridine)2]2+ Cation
Authors: Gou Lei , Xu Li‐Feng , Hu Huai‐Ming , Wang Bao‐Cheng , Wu Qing‐Ran , Chen Xiao‐Li , Tang Zong‐Xun 
Published: May 2008

AbstractBased on the use of [Ni(3‐pytpy)2][BF4]2 (3‐pytpy=4′‐(3‐pyridyl)‐2,2′:6′,2″‐terpyridine) (1) as expanded 3, 3′‐N, N′‐rodlike building blocks and CdII atoms as metal “nodes”, two novel NiII‐CdII heterometallic compounds [Ni(3‐pytpy)2Cd2Cl6] (2) and [Ni(3‐pytpy)2Cd(NCS‐κN)4]·CH3OH (3) have been synthesized under different conditions. In the precursory complex 1, NiII atom is coordinated by the tpy domains of two 3‐pytpy ligands, while the pyridyl tails remain uncoordinated. In compound 2, [Ni(3‐pytpy)2]2+ adopting cis‐conformation bridges two four‐coordinated CdII into trinuclear structure. In compound 3, [Ni(3‐pytpy)2]2+ adopting trans‐conformation connects six‐coordinated CdII into 1D chain and the chains were packed into double‐chains through face‐to‐face π‐π stacking interactions.
Rietveld Analysis and Raman Spectroscopic Investigations on α‐Y2Si2O7
Authors: Kahlenberg V. , Wertl W. , Többens D. M. , Kaindl R. , Schuster P. , Schottenberger H. 
Published: May 2008

AbstractPolycrystalline material of α‐Y2Si2O7has been obtained from the thermal decomposition of a precursor prepared by a sol‐gel process and subsequently characterized by X‐ray powder diffraction and Raman spectroscopy. The structure belongs to the so‐called B‐type of rare earth element disilicates and was refined using the Rietveld method. α‐Y2Si2O7is triclinic with a = 6.58620(3), b = 6.62895(4), c = 12.02723(7) Å, α = 94.4706(4)°, β = 89.0681(4)°, γ = 88.2347(4)°, V = 523.166(5) Å3, space group$P{\bar 1}$, Z = 4 and Dx= 4.39 g/cm3. The structure (Rwp= 4.7 %, RB= 2.9 %) is built from triple tetrahedral [Si3O10]‐groups and isolated [SiO4]‐units, i.e. from a structural point of view it belongs to the group of mixed anion silicates. The silicate anions are located in layers parallel to (1${\bar 1}$1). Linkage between the anionic groups is provided by Y cations having six and eight oxygen neighbours. The corresponding coordination polyhedra can be approximately described as distorted octahedra as well as bicapped trigonal prisms, respectively.
Synthese, Struktur und EPR‐spektroskopische Charakterisierung von Titanocenkomplexen mit Dimethylmalonatoliganden
Authors: Krüger Thomas , Albrecht Carolin , Rüffer Tobias , Lang Heinrich , Griebel Jan , Kirmse Reinhard , Steinborn Dirk 
Published: May 2008

AbstractSynthesis, Structure, and EPR Spectroscopic Characterization of Titanocene Complexes with Dimethylmalonato LigandsThe reaction of [TiCp2(BTMSA)] (1a, Cp = η5‐C5H5, BTMSA = bis(trimethylsilyl)acetylene) with dimethylmalonic acid resulted in the formation of the titanium(III) complex [{TiCp2}2{μ‐(O2C)2CMe2}] (2). Additionally, in an unprecedented case a small amount of the titanium(IV) complex [TiCp2{(O2C)2CMe2‐κO}2] (3) was formed. The identity of complex 2 was confirmed by microanalysis, IR and EPR spectroscopic measurements. Single crystal X‐ray diffraction analysis exhibited a dinuclear structure in which the titanium atoms are distorted tetrahedrally coordinated by two cyclopentadienyl ligands and a κ2O,O′ coordinated dimethylmalonato ligand that acts as bridging ligand, too. Magnetic measurements (μeff = 1.28/Ti, T = 295 K) and EPR investigations both of solutions of 2 in toluene at r.t. and of frozen solutions (T = 130 K) gave proof of a coupling between the two TiIII centres. The fine structure tensor exhibited rhombic symmetry (gx = 1.983, gy = 1.984, gz = 1.979, D = 101·10−4 cm−1, E = 6·10−4 cm−1). Using the equation of Francesconi a Ti···Ti separation of ca 6.3Å was estimated that is in very good agreement with those obtained by X‐ray crystallography (6.685(5) Å). The single‐crystal X‐ray diffraction analysis of [TiCp2{(O2C)2CMe2‐κO}2] (3) exhibited that the Ti centre of 3 is distorted tetrahedrally coordinated by two Cp ligands and two monocoordinated (κO) dimethylmalonato ligands.
Er3F[SiO4][SeO3]2: An ErF3‐Derivative with Two Different Kinds of Complex Oxoanions
Authors: Lipp Christian , Schleid Thomas 
Published: May 2008

AbstractOn our way to close the gap within the lanthanoid(III) fluoride oxoselenate(IV) series of the MF[SeO3] type, where only the compounds with the elements lanthanum and lutetium have been known so far, as a by‐product of the successful synthesis of ErF[SeO3], single crystals of Er3F[SiO4][SeO3]2 appeared occasionally. Er3F[SiO4][SeO3]2 crystallizes orthorhombically in space group Pnna (no. 52) with a = 586.92(4), b = 1529.31(9), c = 1029.67(6) pm and Z = 4. The Er3+ cations reside on two different sites and exhibit coordination numbers of seven and eight. Whereas the [(Er1)O8]13− polyhedra are connected to $^{1}_{\infty}\rm \{[(Er1)(03)^{e}_{4/2}(01)^{t}_{2/1}(04)^{t}_{2/1}]^{9-}\}$ chains, the condensation of the pentagonal bipyramids [(Er2)O6F]10− results in a $^{2}_{\infty}\rm \{[(Er2)(02,5)^{e}_{4/2}(01)^{t}_{1/1}(04)^{t}_{1/1}F^{v}_{1/2}]^{5,5-}\}$ layer. Both chains and sheets are linked to a $^{3}_{\infty}\rm \{[(Er1)(Er2)_{2}O_{10}F]^{12-}\}$ network via common O···O edges. Charge balance is achieved by a single Si4+ and two Se4+ cations which are forming with all available oxygen atoms tetrahedral [SiO4]4− anions and ψ1‐tetrahedral [SeO3]2− anions. The F− anions are attached to only two Er3+ cations generating isolated boomerang‐shaped [F(Er2)2]5+ units. For the synthesis of Er3F[SiO4][SeO3]2 erbium sesquioxide Er2O3, erbium trifluoride ErF3 and selenium dioxide SeO2 (in a molar ratio of 1 : 1 : 3) were reacted with CsBr as fluxing agent for five days at a temperature of 750 °C in evacuated fused silica ampoules. The pink colored transparent crystals of bladed habit did obviously form under otherwise undesired SiO2 activation of the container material.