bluuebunny/crossref_metadata_2025_split huggingface dataset:
Addressing biodiversity conservation, disease surveillance, and public health interventions through One Health approach in Hainan’s tropical rainforest
Authors: Zhang Li , Liu Shoubai , Guo Wenqiang , Lv Chenrui , Liu Xiaomeng 
Published: March 2024

AbstractThis review investigates the utilization of the One Health approach to advance sustainable development and enhance health in the Hainan tropical rainforest, which is a unique ecosystem with significant biodiversity and environmental value. The region is confronted with threats arising from human activities and climate change, impacting both the health of the inhabitants and the ecosystem. The Hainan tropical rainforests create an ideal habitat for the transmission of mosquito-borne diseases, such as dengue fever and malaria, between humans and animals. The hot and humid climate creates favorable conditions for mosquito proliferation, while increased human encroachment into forested areas escalates the risk of contact with wildlife reservoirs of these diseases. Proactive surveillance of emerging infectious diseases in the forests and animal populations of Hainan is crucial for early detection and swift response to potential public health hazards. By embracing the interdisciplinary and collaborative principles of the One Health approach, this review aims to safeguard the ecosystem while fostering development. The introduction offers insights into the significance of the One Health concept, its relevance to environmental conservation, human health, and animal health. Subsequently, the paper delves into the practical application of the One Health approach in the Hainan tropical rainforest, using it as a case study. This application entails raising awareness of ecosystem health through educational initiatives and public outreach, implementing effective ecological conservation measures, promoting wildlife conservation efforts, and monitoring and preventing potential disease outbreaks. Furthermore, the paper highlights the importance of the One Health approach in achieving sustainable development in the Hainan tropical rainforest. It also explores potential research directions and associated challenges. By prioritizing the collective well-being of humans, animals, and the environment, the One Health approach offers a means to balance ecosystem conservation and human welfare.
Pyroptosis-Derived Long Noncoding RNA Profiles Reveal a Novel Signature for Evaluating the Prognosis of Patients With Lung Adenocarcinoma
Authors: Ba Yuhao , Liu Shutong , Wei Zhengpan , Zhao Nannan , Qiao Tong , Ren Yuqing , Li Lifeng , Zhang Yuyuan , Weng Siyuan , Xu Hui , Li Chunwei , Ge Xiaoyong , Han Xinwei 
Published: March 2024

PURPOSE Long noncoding RNAs (lncRNAs) were recently implicated in modifying pyroptosis. Nonetheless, pyroptosis-related lncRNAs and their possible clinical relevance persist largely uninvestigated in lung adenocarcinoma (LUAD). MATERIALS AND METHODS A sum of 921 samples were collected from three independent data sets. We obtained pyroptosis-related genes from both the Molecular Signatures Database and relevant literature sources and used four machine learning techniques, comprising stepwise Cox, ridge regression, least absolute shrinkage and selection operator, and random forest. Multiple bioinformatics approaches were used to further investigate the underlying mechanisms. RESULTS In total, 39 differentially expressed pyroptosis genes were identified by comparing normal and tumor samples. Correlation analysis revealed 933 pyroptosis-related lncRNAs. Furthermore, univariate Cox regression determined 11 lncRNAs that exhibited stable associations with prognosis in the three cohorts, which were used to construct the pyroptosis-derived lncRNA signature. After analyzing the optimal results from four machine learning algorithms, we ultimately selected random forest to develop the pyroptosis-derived lncRNA signature. This signature was proven to be an independent prognostic factor and exhibited robust performance in three cohorts. CONCLUSION We provided novel insight and established a pyroptosis-derived lncRNA signature for patients with LUAD, exhibiting strong predictive capabilities in both the training and validation sets.
Cocoa at Work: Materials and Labor in the Making of Global Chocolate
Authors: Macedo Marta 
Published: March 2024

Abstract
This article examines two distant workspaces of cocoa: plantations in São Tomé, a small Portuguese colonial island in the African Gulf of Guinea, and a British chocolate factory. In line with commodity-centered histories, it focuses on the diversity of labor systems, with different levels of coercion, working simultaneously to make cocoa and chocolate available to consumers in the industrial cities of Europe and North America. But this article adds to that literature by embracing the challenge of thinking with materials and the ways they produced specific social worlds. Cocoa and chocolate are understood as “thick things” whose physical attributes allowed or restricted different operations and uses and whose characteristics promoted or obstructed particular labor forms and allowed for the stabilization of different modes of rule. When we take the material properties of cocoa seriously, it is possible to see how mass chocolate production was a technological and scientific enterprise conceived to cope with the constraints of cocoa itself, with profound consequences for the labor forms on the plantation and the factory. Materials bound plantation laborers and chocolate scientists to specific technological, economic and political relations and demanded huge investments and much labor to create alternative ones.
Electric Discipline: Gendering Power and Defining Work in Electric Power Systems
Authors: Kahle Trish 
Published: March 2024

Abstract
In the 1970s, energy conservation was a household idea, but it was also a form of labor discipline. This article shows how one utility, the Pennsylvania Power & Light Company (PP&L), used energy conservation to discipline unwaged workers in the home, upending decades of home economics research that sought to substitute electric energy for human energy in housework. To effectively deploy this strategy, PP&L drew on utilities’ well-established understanding of women's unwaged work in the home as central to balancing the rhythms of power demand. By exploring this history, this article also argues that by adopting a more expansive understanding of labor in energy systems—which I term “energy work”—we can better understand the interrelationship of labor, gender, and power in the operation of energy systems and more fully incorporate the history of unwaged workers into the history of energy.
Physiological Factors Associated with Unsatisfied Inspiration at Peak Exercise in Healthy Adults
Authors: Ferguson Olivia N. , Mitchell Reid A. , Schaeffer Michele R. , Ramsook Andrew H. , Boyle Kyle G.P.J.M , Dhillon Satvir S. , Zhang Julia , Hind Alanna S. , Jensen Dennis , Guenette Jordan A. 
Published: March 2024

ABSTRACT

Introduction
Contrary to common belief, a growing body of evidence suggests that unsatisfied inspiration (UI), an inherently uncomfortable quality of dyspnea, is experienced by ostensibly healthy adults during high-intensity exercise. Based on our understanding of the mechanisms of UI among people with chronic respiratory conditions, this analysis tested the hypothesis that the experience of UI at peak exercise in young, healthy adults reflects the combination of high ventilatory demand and critical inspiratory constraints.

Methods
In a retrospective analysis design, data included 321 healthy individuals (129 females) aged 25 ± 5 yrs. Data were collected during one visit to the laboratory, which included anthropometrics, spirometry, and an incremental cardiopulmonary cycling test to exhaustion. Metabolic and cardiorespiratory variables were measured at peak exercise, and qualitative descriptors of dyspnea at peak exercise were assessed using a list of 15 descriptor phrases.

Results
34% of participants (n = 109) reported sensations of UI at peak exercise. Compared to the Non-UI group, the UI group achieved a significantly higher peak work rate (243 ± 77 vs. 235 ± 69 W, P = 0.016, d = 0.10), rate of O2 consumption (3.32 ± 1.02 vs. 3.27 ± 0.96 L·min−1, P = 0.018, d = 0.05), minute ventilation (120 ± 38 vs. 116 ± 35 L·min−1, P = 0.047, d = 0.11), and breathing frequency (50 ± 9 vs. 47 ± 9 breaths·min−1, P = 0.014, d = 0.33), while having a lower exercise-induced change (peak-baseline) in inspiratory capacity (0.07 ± 0.41 vs. 0.20 ± 0.49 L, P = 0.023, d = 0.29). The inspiratory reserve volume to minute ventilation ratio at peak exercise was also lower in the UI vs. Non-UI group. Dyspnea intensity and unpleasantness ratings were significantly higher in the UI vs. Non-UI group at peak exercise (both P < 0.001).

Conclusions
Healthy individuals reporting UI at peak exercise have relatively greater inspiratory constraints compared to those who do not select UI.
Lower Extremity Kinematic and Kinetic Characteristics as Effects on Running Economy of Recreational Runners
Authors: CHEN SHIQIN , SEGERS VEERLE , ZHANG QINGSHAN , ZHANG QIN , DING HAIYONG , LI FEI 
Published: March 2024

ABSTRACT

Purpose
This study aimed to determine associations between running economy (RE) and running sagittal plane kinematic and kinetic parameters.

Method
A total of 30 male recreational runners (age: 21.21 ± 1.22 yr, V̇O2max: 54.61 ± 5.42 mL·kg−1·min−1) participated in two separate test sessions. In the first session, the participant’s body composition and RE at 10 and 12 km·h−1 were measured. In the second session, measurements were taken for the sagittal plane of hip, knee, and ankle angles and range of motion (ROM), as well as ground reaction force.

Results
Moderate correlations were found between lower energy costs at 12 km·h−1 and smaller hip flexion at toe-off (r = 0.373) as well as smaller peak hip flexion during stance (r = 0.397). During the swing phase, lower energy costs at 10 km·h−1 were moderately correlated with smaller peak knee flexion and smaller knee flexion and extension ROM (r = 0.366–0.443). Lower energy costs at 12 km·h−1 were moderately correlated with smaller peak hip and knee flexion as well as knee extension ROM (r = 0.369–0.427). In terms of kinetics, there was a moderate correlation between higher energy costs at 10 km·h−1 and larger peak active force, as well as larger peak braking and propulsion force (r = −0.470–0.488). Lower energy costs at 12 km·h−1 were moderately to largely correlated with smaller peak impact and braking force (r = 0.486 and −0.500, respectively). Regarding the statistical parametric mapping analysis, most outcomes showed associations with RE at 10 km·h−1, including knee flexion (42.5%–65.5% of the gait cycle), ankle plantarflexion (32.5%–36% of the gait cycle), active force (30.5%–35% of the stance phase), and propulsion force (68%–72.5% of the stance phase). Lower energy costs at 12 km·h−1 were correlated with smaller hip flexion (5.5%–12% and 66.5%–74%) and smaller knee flexion (57%–57.5%) during the running gait cycle.

Conclusions
This study indicates that biomechanical factors are associated with RE in recreational runners. To design effective training methods to improve RE, coaches and runners should focus on the sagittal plane kinematics of the hip, knee, and ankle, as well as lower vertical and horizontal kinetic parameters.
When Tariffs Disrupt Global Supply Chains
Authors: Grossman Gene M. , Helpman Elhanan , Redding Stephen J. 
Published: March 2024

We study unanticipated tariffs in a setting with firm-to-firm supply relationships. Firms conduct costly searches and negotiate with potential suppliers that pass a reservation level of match productivity. Global supply chains form in anticipation of free trade. Then, the home government surprises with an input tariff. This can lead to renegotiation with initial suppliers or search for replacements. Calibrating the model’s parameters to match initial import shares and the estimated responses to the US tariffs imposed on China, we find an overall welfare loss of 0.12 percent of GDP, with substantial contributions from changes in input sourcing and search costs. (JEL D72, F13, F14, L14, O19, P33)
An Evaluation of Low-Grade Red Oak and Soft Maple as Raw Material for Cross-Laminated Timber Panel Production
Authors: Hassler Curt C. , Young Matt , Denes Levente , Bencsik Balazs , McNeel J. F. 
Published: March 2024

Abstract
Utilization of hardwoods in the manufacture of cross-laminated timber (CLT) faces many challenges, one of which is the selection of raw material that is both technically and economically feasible. From an economic perspective, it would make sense to choose species and grades that are both readily available and relatively competitive with softwood species currently used in CLT manufacturing. For the purposes of this study, lower grades (2A Common, 2B Common, 3A Common, and 3B Common) of red oak and soft maple were deemed appropriate in fitting this profile.
All lumber was visually graded according to both National Hardwood Lumber Association (NHLA) and Northeastern Lumber Manufacturers Association (NeLMA) grading rules, as well as nondestructively tested through flatwise bending to determine modulus of elasticity (MOE). The yield distribution of each species and NHLA grade, by visual structural grade, were analyzed. The mechanical testing of each species was analyzed based on the minimum allowable MOE of 1.2 x 106 psi as required by ANSI/PRG-320. Mechanical testing resulted in much higher yields of acceptable CLT material than visual grading, for both species.
A total net worth analysis was conducted to evaluate the value of NHLA graded lumber being processed into structurally graded lumber for both species and both grading methods. Finally, a procurement analysis was conducted to determine the volume of lumber required for both species, in order to achieve a fixed volume of CLT-ready lumber.
Experimental demonstration of a multi-core fiber seeded comb optical network (MCF-SCON)
Authors: Puttnam B. J. , Luis R. S. , Orsuti D. , Rademacher G. , Di Sciullo G. , van den Hout M. , Sakaguchi J. , Antonelli C. , Okonkwo C. , Palmieri L. , Furukawa H. 
Published: March 2024

We propose and experimentally demonstrate an optical network architecture that uses wideband optical frequency comb (OFC) sources synchronized with transmitted network broadcast seed signals. All network nodes are connected by multi-core fibers (MCFs) which are used for data transmission and seed distribution. The nodes that connect the data transmission and seed distribution layers contain an OFC that may be operated in master or slave mode to provide carriers both for modulation and local oscillators for coherent detection. Nodes are able to switch, amplify, split, and regenerate the seed lightwave for full network distribution over large areas. Using OFCs with 25 GHz spacing covering the C- and L-bands, we experimentally investigate a range of scenarios compatible with metro or inter-data-center network architectures. These scenarios include single span transmission, bi-directional transmission, and multi-hop seed and data transmission including seed amplification, splitting, and regeneration with laser injection locking within network nodes, and a maximum transmission distance of 130 km. We show that MCF seed and data distribution with spatial-switching enables identical network-wide transceiver combs with the potential for reducing the complexity of digital signal processing as well as significant hardware sharing. Data-rates of approximately 100 Tb/s/core and 600 Tb/s per fiber are measured showing the potential of this architecture for high-capacity networking with OFCs replacing hundreds of transmitter and local oscillator lasers in each node.
From opt-out to opt-in consent for secondary use of medical data and residual biomaterial: An evaluation using the RE-AIM framework
Authors: Lutomski Jennifer E. , Manders Peggy 
Published: March 2024

Background
Patient records, imaging, and residual biomaterial from clinical procedures are crucial resources for medical research. In the Netherlands, consent for secondary research has historically relied on opt-out consent. For ethical-legal experts who purport passive consent undermines patient autonomy, opt-in consent (wherein affirmative action is required) is seen as the preferred standard. To date, there is little empirical research exploring patient feasibility, organizational consequences, and the potential risks for research based on secondary data. Thus, we applied the RE-AIM framework to evaluate the impact of migrating from an opt-out to an opt-in consent process.

Methods
This evaluation was carried out in Radboud University Medical Center, a large tertiary hospital located in the southeast of the Netherlands. All non-acute, mentally competent patients ≥16 years of age registered between January 13, 2020 and June 30, 2023 were targeted (N = 101,437). In line with the RE-AIM framework, individual and organizational consequences were evaluated across five domains: reach, efficacy, adoption, implementation, and maintenance.

Results
101,437 eligible patients were approached of whom 66,214 (65.3%) consented, 8,059 (7.9%) refused consent and 27,164 (26.8%) had no response. Of the 74,273 patients with a response, 89.1% consented to secondary use. The migration to an opt-in consent system was modestly successful; yet notably, differential response patterns by key sociodemographic characteristics were observed. Adaptions to the process flow improved its effectiveness and resulted in a reasonable response over time. Implementation was most affected by budgetary restraints, thus impeding the iterative approach which could have further improved domain outcomes.

Conclusion
This evaluation provides an overview of logistical and pragmatic issues encountered when migrating from opt-out to opt-in consent. Response bias remains a major concern. Though not always directly transferable, these lessons can be broadly used to inform other health care organizations of the potential advantages and pitfalls of an opt-in consent system.
A pilot randomised controlled trial comparing the effectiveness of the MaTerre180’ participatory tool including a serious game versus an intervention including carbon footprint awareness-raising on behaviours among academia members in France
Authors: Teran-Escobar Claudia , Becu Nicolas , Champollion Nicolas , Gratiot Nicolas , Hingray Benoît , Panthou Gérémy , Ruin Isabelle 
Published: March 2024

Background
Activities embedded in academic culture (international conferences, field missions) are an important source of greenhouse gas emissions. For this reason, collective efforts are still needed to lower the carbon footprint of Academia. Serious games are often used to promote ecological transition. Nevertheless, most evaluations of their effects focus on changes in knowledge and not on behaviour. The main objectives of this study are to 1) Evaluate the feasibility of a control and an experimental behaviour change intervention and, 2) Evaluate the fidelity (the extent to which the implementation of the study corresponds to the original design) of both interventions.

Methods
People employed by a French research organisation (N = 30) will be randomised to one of the two arms. The experimental arm consists in a 1-hour group discussion for raising awareness about climate change, carrying out a carbon footprint assessment and participating to a serious game called “Ma terre en 180 minutes.” The control arm consists of the same intervention (1h discussion + carbon footprint assessment) but without participating to the serious game. On two occasions over one month, participants will be asked to fill in online surveys about their behaviours, psychological constructs related to behaviour change, sociodemographic and institutional information. For every session of intervention, the facilitators will assess task completion, perceived complexity of the tasks and the perceived responsiveness of participants. Descriptive statistics will be done to analyse percentages and averages of the different outcomes.

Discussion
Ma-terre EVAL pilot study is a 1-month and a half pilot randomised controlled trial aiming to evaluate the feasibility and the fidelity of a 24-month randomised controlled trial. This study will provide more information on the levers and obstacles to reducing the carbon footprint among Academia members, so that they can be targeted through behaviour change interventions or institutional policies.
A szociálisprobléma-megoldás, a megküzdési stratégiák és az asszertív kommunikáció jellemzői 5. és 7. osztályosok körében
Authors: Balogh-Pécsi Anett 
Published: March 2024

A vizsgálat célja a szociálisprobléma-megoldás, a megküzdési stratégiák és az asszertív kommunikáció jellemzőinek feltárása volt 5. osztályos és 7. osztályos tanulók körében (N = 378). A kommunikációt az Assertiveness Questionnaire (AQ, Gaumer Erickson et al., 2016), a szociálisprobléma-megoldást a Social Problem-Solving Inventory-Revised (SPSI-R, D'Zurilla et al., 2002), a megküzdési stratégiákat pedig a Ways of Coping Questionnaire (WCQ, Folkmann & Lazarus, 1988) segítségével vizsgáltuk. Az eredmények alapján a három szociális területen többnyire szignifikáns különbségek vannak az 5. és a 7. évfolyamosok között. A negatív problémaorientáció gyakoribb az idősebb tanulók körében, és az életkori különbségen túlmenően számos olyan terület van, ahol a fiúk és a lányok értékei még a fiatalabb tanulók körében is különböznek (pl. a lányok körében gyakoribb a konfrontáció, a fiúk körében az elkerülés). Az eredmények a korábbinál árnyaltabb képet adnak a fiúk problémamegoldásáról, kommunikációjáról és ezek kapcsolatáról.
Elemzésünk eredményei alapján megállapítható, hogy a kérdőívek alkalmazásával nyert adatok alkalmasak tudományos igényű következtetések levonására.
Granulomatous Hepatitis Treated With Certolizumab Pegol
Authors: Brittan Kevin , Fiedler Alexandra , Scholten Kyle , Songtanin Busara , Manatsathit Shane 
Published: March 2024

ABSTRACT
Idiopathic granulomatous hepatitis is a rare condition characterized by hepatic granulomas with constitutional symptoms such as recurrent fevers, myalgias, and hepatosplenomegaly in the absence of infection or inflammatory disorder. Typical treatment and course of this disease consist of a course of steroids with rapid symptom resolution. However, symptoms may recur when steroids are tapered. In these circumstances, azathioprine, methotrexate, infliximab, and adalimumab have demonstrated good response. In this case, we present a patient who developed antidrug antibodies to infliximab and adalimumab and was the first documented case of this disease to be treated with certolizumab pegol. Our case highlights the novel efficacy of certolizumab pegol for idiopathic granulomatous hepatitis and its role in treating idiopathic granulomatous hepatitis with antidrug antibodies.
Successful Treatment of Refractory Chylous Ascites With Octreotide in a Patient With Decompensated Cirrhosis
Authors: DiBattista Jacob V. , Odenwald Matthew A. , Te Helen 
Published: March 2024

ABSTRACT
Chylous ascites is a rare manifestation of decompensated cirrhosis that is associated with increased short-term mortality. Exclusion of other etiologies must be performed to allow for appropriate management, which itself can be a challenge in the setting of decompensated cirrhosis. We report a case of chylous ascites in a patient with decompensated cirrhosis that was successfully managed with octreotide before liver transplantation.