bluuebunny/crossref_metadata_2025_split huggingface dataset:
The 40S ribosomal protein SA-2 inhibits citrus yellow vein clearing virus infection in Eureka lemon via activating jasmonic acid and photosynthetic pathways
Authors: Liao Ping , Huangfu Mengyang , Ding Dongdong , Dan Xue , Chen Li , Lou Binghai , Zhou Yan 
Published: February 2025

Abstract
The 40S ribosomal protein SA (RPSA) functions as an important regulatory factor in plant resistance to abiotic stresses. However, the role of RPSA in response to plant virus infection is poorly understood. Citrus yellow vein clearing virus (CYVCV) has a significantly negative impact on citrus production, and its coat protein (CP) is involved in viral pathogenicity. In this study, we revealed the interaction of CP with Eureka lemon 40S RPSA (ClRPSA-2) in the nucleus, membrane, and endoplasmic reticulum of Nicotiana benthamiana. Further experiments demonstrated that the ClRPSA-2 N-terminal conserved region (amino acids 22—122) was involved in the interaction with CP, and the ClRPSA-2 expression in young Eureka lemon leaves significantly reduced. Transient expression of ClRPSA-2 triggered the expression of jasmonic acid (JA), photosynthetic pathway- and resistance-related genes, as well as increased the JA content and maximum photochemical efficiency (Fv/Fm) in lemon. Furthermore, ClRPSA-2 negatively regulated CYVCV resistance in plants, which induced resistance to other citrus viruses. These findings enhance our understanding of the interaction between CYVCV and citrus plants and provide a basis for future research on resistance breeding of citrus.
Exploring the effects of alpha-pinene on apoptosis induction in human colon cancer cells via the PI3K/AKT signaling pathway: an in vitro study
Authors: Shafieipour Sara , Zamanian Yasaman , Hadipour Elham , Sinaei Reza , Khoshnazar Seyedeh Mahdieh 
Published: February 2025

Abstract

Background
Colorectal carcinoma ranks as the second most prevalent neoplasm in females and the third most prevalent in males.

Methods
In this investigation, we examined the influence of alpha-pinene (ALP), classified as a monoterpene, on the proliferation of HT-29 human colorectal carcinoma cells via the PI3K/AKT signaling cascade. HT-29 cells were exposed to a range of ALP concentrations. The survival rate of the cells was assessed through the MTT assay; while, apoptotic events were evaluated using flow cytometry in conjunction with Annexin V/PI staining. Additionally, cell cycle dynamics were scrutinized through fluorescence-activated cell sorting. The expression levels of Bax, Bcl-2, Caspase-3, PI3K, and AKT at both the gene and protein levels were quantified employing real-time PCR and western blot techniques.

Results
ALP treatment led to a significant, dose-dependent decrease in cell viability, with prolonged exposure exacerbating cytotoxic effects. Apoptosis analysis showed that ALP significantly increased apoptotic cells after 24 h of treatment. Cell cycle analysis showed that ALP induces G2/M phase arrest and inhibits cell proliferation and DNA synthesis. Gene expression analysis revealed upregulation of pro-apoptotic genes Bax and caspase-3 and decreased anti-apoptotic gene Bcl-2. Furthermore, the administration of ALP led to a notable reduction in both the gene and protein expression levels of PI3K and Akt, suggesting a suppression of the PI3K/Akt signaling cascade.

Conclusion
ALP inhibits HT-29 colon cancer cell growth by reducing cell viability, inducing apoptosis, and blocking the PI3K/AKT pathway. These findings highlight ALP’s potential as a therapeutic candidate for colorectal cancer.
Formação de Alfabetizadores na/da/para a EJA: a Experiência de um Grupo de Estudos no Âmbito de um Projeto de Extensão
Authors: Silva Jaqueline Luzia da , Silva Camila Vitoria Sousa da 
Published: February 2025

Este trabalho apresenta um relato de experiência cujo objetivo é descrever a experiência vivenciada no grupo de estudos “Desafios e possibilidades atuais na alfabetização de jovens e adultos”, vinculado a um projeto de extensão universitária da Faculdade de Educação da Universidade do Estado do Rio de Janeiro (UERJ). Este grupo permanente procura contribuir com a formação inicial ou continuada dos participantes, fomentando a reflexão e a pesquisa sobre as práticas pedagógicas de alfabetizadores na Educação de Jovens e Adultos (EJA) a partir das leituras e estudos realizados nos encontros. Foi escolhida a metodologia de descrição das experiências e vivências e realizou-se uma abordagem qualitativa, evidenciando os aspectos que consideramos mais relevantes para a construção deste relato. Ao longo das vivências neste grupo, foi possível perceber uma pedagogia ativa, dialógica e interativa, capaz de impulsionar a construção de conhecimentos e aprendizados por meio da interação de todos os participantes, tecendo múltiplas aprendizagens e reflexões. As conclusões apontam para a importância do rompimento com práticas educativas limitantes e, também, demonstram que a formação de educadores pode contribuir para o enfrentamento dos desafios impostos pela realidade, fomentando reflexões críticas e propondo novos caminhos de atuação.
Palavras-chave: Educação de Jovens e Adultos (EJA); Formação de professores; Alfabetização.

Training Literacy Teachers in/of/for the EJA: the Experience of a Study Group as Part of an Extension Project
This paper presents an experience report, whose objective is to describe the experience live in the study group “Desafios e possibilidades atuais na alfabetização de jovens e adultos”, linked to a university extension project of the Faculty of Faculty of Education of the Universidade do Estado do Rio de Janeiro (UERJ). This permanent group seeks to contribute to the initial or continuing education of the participants, fostering reflection and research on the pedagogical practices of literacy teachers in Youth and Adult Education (EJA) based on the readings and studies carried out at the meetings. The methodology of description of the experiences was chosen and a qualitative approach was carried, highlighting the aspects that we consider most relevant for the construction of this report. Throughout the experiences in this group, it was possible to perceive an active, dialogical and interactive pedagogy, capable of boost the construction of knowledge and learning trough the interaction of all participants, weaving multiple learnings and reflexions. The conclusions point to the importance of breaking away from limiting educational practices and also show that the training of educators can contribute to meeting the challenges imposed by reality, fostering critical reflection and proposing new ways of working.
Keywords: Youth and Adult Education (YAE); Teacher training; Literacy.
Childhood brain morphometry in children with persistent stunting and catch-up growth
Authors: Koshy Beena , Thilagarajan Vedha Viyas , Berkins Samuel , Banerjee Arpan , Srinivasan Manikandan , Livingstone Roshan S. , Mohan Venkata Raghava , Scharf Rebecca , Jasper Anitha , Kang Gagandeep 
Published: February 2025

Background
Early childhood stunting affects around 150 million young children worldwide and leads to suboptimal human potential in later life. However, there is limited data on the effects of early childhood stunting and catch-up growth on brain morphometry.

Methods
We evaluated childhood brain volumes at nine years of age in a community-based birth-cohort follow-up study in Vellore, south India among four groups based on anthropometric assessments at two, five, and nine years namely ‘Never Stunted’ (NS), ‘Stunted at two years and caught up by five years’ (S2N5), ‘Stunted at two and five years and caught up by nine years’ (S2N9), and ‘Always Stunted’ (AS). T1-weighted magnetic resonance imaging (MRI) images were acquired using a 3T MRI scanner, and brain volumes were quantified using FreeSurfer software. Analysis of Variance (ANOVA) was used to determine the differences in brain volumetry between the stunting groups, with age and sex as covariates. The effect size ANOVA models was evaluated using Eta squared.

Findings
Amongst 251 children from the initial cohort, 178 children with a mean age of 9.54 underwent neuroimaging and considered for further analysis. The total brain volume, subcortical volume, bilateral cerebellar white matter, and posterior corpus callosum showed a declining trend from NS to AS. Regional cortical brain analysis showed significant lower bilateral lateral occipital volumes, right pallidum, bilateral caudate, and right thalamus volumes between NS and AS.

Interpretation
To the best of our knowledge, this first neuroimaging analysis to investigate the effects of persistent childhood stunting and catch-up growth on brain volumetry indicates impairment at different brain levels involving total brain and subcortical volumes, networking/connecting centres (thalamus, basal ganglia, callosum, cerebellum) and visual processing area of lateral occipital cortex.
Home-based nurturing care practices for children under five with low socioeconomic position in Santo Domingo, Dominican Republic
Authors: Nelson Adrianne Katrina , Sánchez-Vincitore Laura , Patricia Frias Melanie , Susana Michelle Marie , Kendall Carl , Theall Katherine , Vibbert Martha , Luft Heidi , Castro Arachu 
Published: February 2025

Background
In the Dominican Republic about 14.5% of children do not reach their full potential by age five, with children of low socioeconomic position most affected. The Nurturing Care Framework is an evidence-informed actionable framework to help children thrive, but we must first understand cultural contexts and childrearing practices that contribute to delay. This study applies the Nurturing Care Framework to explore the context of home-based care among young children in the Dominican Republic.

Methods
We conducted a sociodemographic survey and semi-structured qualitative interview with 25 mothers ages 19–42 (7 under the age of 18 at first birth) with low socioeconomic position and children under five that live in the capital city Santo Domingo. We asked in-depth questions about the Nurturing Care Framework’s domains of responsive caregiving and opportunities for early learning. We used consensual coding and deductive thematic analysis to analyze transcriptions, examined convergence and divergence in themes between adolescent and adult mothers, and organized themes using concept mapping.

Results
A few mothers provide responsive caregiving to their child, but they are unaware of its benefit to their child’s development. Adolescent mothers expressed lower confidence in their mothering skills. Across age groups, mothers did not see themselves as agents of change in their child’s early learning process and allow several hours of videos each day. Mothers provide children opportunities for learning through social interaction, a possible strength among this population. With regards to security and safety, about half of mothers use corporal punishment, all but one of these is an adolescent mother.

Conclusion
Findings highlight the need for parenting programs that build on strengths such as child-to-child social interaction and provide parents with opportunities to develop knowledge and skills to provide early learning opportunities. Interventions should target families with low socioeconomic position and adolescent mothers.
Acceptability and implementation potential of colorectal cancer screening and health literacy training: A qualitative study among general practitioners in deprived areas
Authors: Cazorla Géraldine , Redmond Niamh M. , Lamouroux Aurore , Boirot Alix , Rotily Michel , Addamiano Maria Claudia , Balamou Christian , Doukhi Zineb , Kaou Myriam , Couranjou Françoise , Delpierre Cyrille , Mancini Julien , Durand Marie-Anne 
Published: February 2025

Background
Colorectal cancer (CRC) is a significant contributor to cancer-related burden, ranking second in cancer mortality in France. Despite the proven survival benefits of systematic CRC screening, uptake remains suboptimal, particularly among people with limited health literacy (HL) and lower socioeconomic position. This study aimed to assess the acceptability of an e-learning training programme on HL and CRC screening among general practitioners (GPs) in deprived areas while also exploring strategies for its promotion and scale-up.

Methods
A qualitative study nested within the DECODE cluster-randomised controlled trial (NCT04631692) across four French regions was conducted. Semi-structured interviews (phone or online) were carried out to capture opinions, experiences, and recommendations of GPs in the intervention arm. Thematic analysis, employing manual and NVivo coding, was performed.

Results
The majority of 22 GPs (16/22) found the training acceptable, informative, tailored to their knowledge needs and offering great flexibility of use. The module on HL garnered more interest than the one on CRC screening, as it addressed a relatively new area for many GPs. It facilitated reflection on patient communication techniques and identified areas for improvement in physician-patient interaction. A perceived gap in the training was the insufficient interactivity in both didactic and virtual group sessions.

Conclusion
The findings of this study show high acceptability of the e-learning training by participants, indicating a potential for implementation, if kept concise, self-paced, asynchronous, and with a stronger focus on HL. The training helped GPs reflect on their practices, enhance HL knowledge, and improve patient communication strategies, leading some to adopt new techniques in daily interactions with low HL patients, beyond just screening.
Association between glycosylated hemoglobin and blood lead: A cross-sectional study
Authors: Wang Wei , Jing Pengfei , Zhao Hongsen , Cheng Jibo , Yang Zewei , He Fan , Lv Shuquan 
Published: February 2025

Background
Diabetes is the most common chronic metabolic disease, affecting many people's health. Previous studies have shown a close relationship between trace elements and metabolic diseases. This study investigated the interrelationship between glycosylated hemoglobin (HbA1c) and blood lead (BPb) in adults.

Method
This research was carried out involving 12,049 eligible individuals aged 20 years or above from the National Health and Nutrition Examination Survey (NHANES) spanning from 2011 to 2020. Weighted linear regression models and smoothed curve fitting were employed to investigate the association between HbA1c and blood lead. Analyses were stratified based on age, sex, race, and body mass index, and threshold effects were explored using two-stage segmented linear regression models.

Result
Among all 12049 participants, through comprehensive adjustment of the model, this study discovered a negative association between HbA1c and blood lead. In addition, when stratified by sex, age, race, and BMI status in subgroup analysis in this study, this correlation still had specific statistical significance. In performing subgroup analyses, we found that the relationship between HbA1c and blood lead may yield distinct outcomes arise from gender disparities. In women, a significant U-shaped association exists between HbA1c and BPb. At approximately 6.6% of HbA1c value, the relationship between the two shifts from negative to positive.

Conclusion
This investigation proposes a “U” form association between HbA1c and BPb in American adults.
Cosmetics Marketing: Strategy and Innovation in the Beauty Industry, Lindsay Karchin and Delphine Horvath (2023)
Authors: Arrington Deidra W. 
Published: February 2025

Review of: Cosmetics Marketing: Strategy and Innovation in the Beauty Industry, Lindsay Karchin and Delphine Horvath (2023)
London: Bloomsbury Visual Arts, 253 pp.,
ISBN 978-1-35029-943-6, p/bk, $44.95
New Approaches to Decolonizing Fashion History and Period Styles: Refashioning Pedagogies, Ashley Bellet (ed.) (2024)
Authors: Becker Payton 
Published: February 2025

Review of: New Approaches to Decolonizing Fashion History and Period Styles: Refashioning Pedagogies, Ashley Bellet (ed.) (2024)
New York: Routledge, 228 pp.,
ISBN 978-1-03223-542-4, p/bk, $42.95
Shirts, Shifts and Sheets of Fine Linen: British Seamstresses from the 17th to the 19th Century, Pam Inder (2024)
Authors: Lamb Renée 
Published: February 2025

Review of: Shirts, Shifts and Sheets of Fine Linen: British Seamstresses from the 17th to the 19th Century, Pam Inder (2024)
London: Bloomsbury Visual Arts, 311 pp.,
ISBN 978-1-35025-296-7, h/bk, $115.00
ISBN 978-1-35025-297-4, e-PDF, $103.50
ISBN 978-1-35025-298-1, e-book, $103.50
Hang Ups: Reflections on the Causes and Consequences of Fashion’s ‘Western’-Centrism, Benjamin Linley Wild (2024)
Authors: Sperling Joy 
Published: February 2025

Review of: Hang Ups: Reflections on the Causes and Consequences of Fashion’s ‘Western’-Centrism, Benjamin Linley Wild (2024)
London, New York, New Delhi and Sydney: Bloomsbury Visual Arts, 292 pp.,
ISBN 978-1-35019-724-4, h/bk, $103.50
ISBN 978-1-35019-723-7, p/bk, $34.15
ISBN 978-1-35019-725-1, e-PDF, $27.32
ISBN 978-1-35019-726-8, e-book, $27.32
Complicated Diverticulitis: A Rare Long-Term Complication After Esophagectomy With Colon Interposition
Authors: Veenstra Fokkelein , van Duyn Eino , Venneman Niels G. , van den Beukel Barend 
Published: February 2025

ABSTRACT
Colon interposition, a rare esophageal reconstructive procedure, can lead to late complications such as diverticulitis in the transplanted colon segment. This case involves a 65-year-old man who presented with a neck swelling 60 years after a colon interposition following caustic ingestion. A diagnosis of diverticulitis with an abscess was confirmed on a computed tomography scan after an initial diagnosis of diverticulitis, and subsequent abscess drainage was performed. Despite the development of a colocutaneous fistula, it closed spontaneously after eight weeks. The pathophysiology involves altered colonic conditions postsurgery. Management includes antibiotics and drainage, but treatment for such fistulas remains uncertain, requiring a tailored approach.
CUTTANA: Scalable Graph Partitioning for Faster Distributed Graph Databases and Analytics
Authors: Hajidehi Milad Rezaei , Sridhar Sraavan , Seltzer Margo 
Published: February 2025

Graph partitioning plays a pivotal role in various distributed graph processing applications, including graph analytics, graph neural network training, and distributed graph databases. A "good" graph partitioner reduces workload execution time, worker imbalance, and network overhead. Graphs that require distributed settings are often too large to fit in the main memory of a single machine. This challenge renders traditional in-memory graph partitioners infeasible, leading to the emergence of streaming solutions. Streaming partitioners produce lower-quality partitions, because they work from partial information and must make premature decisions before they have a complete view of a vertex's neighborhood. We introduce CUTTANA, a streaming graph partitioner that partitions massive graphs (Web/Twitter scale) with superior quality compared to existing streaming solutions. CUTTANA uses a novel buffering technique that prevents the premature assignment of vertices to partitions and a scalable coarsening and refinement technique that enables a complete graph view, improving the intermediate assignment made by a streaming partitioner. We implemented a parallel version for CUTTANA that offers nearly the same partitioning latency as existing streaming partitioners.
Our experimental analysis shows that CUTTANA consistently yields better partitioning quality than state-of-the-art streaming vertex partitioners in terms of both edge-cut and communication volume metrics. We also evaluate the workload latencies that result from using CUTTANA and other partitioners in distributed graph analytics and databases. CUTTANA outperforms the other methods in most scenarios (algorithms, datasets). In analytics applications, CUTTANA improves runtime performance by up to 59% compared to various streaming partitioners (i.e., HDRF, Fennel, Ginger, HeiStream). In graph database tasks, CUTTANA results in higher query throughput by up to 23%, without hurting tail latency.
Exploring the role of beta‐endorphin in activity‐based anorexia in mice
Authors: Christensen Connor W. , Weed Samantha E. , Brown Travis E. , Hentges Shane T. 
Published: February 2025

AbstractAnorexia nervosa (AN) remains one of the most lethal mental health disorders and is poorly understood from a neurobiological perspective. The most widely used animal model of AN is activity‐based anorexia (ABA) where scheduled food presentation leads to a spontaneous maladaptive increase in running‐wheel activity and rapid weight loss in rodents, recapitulating specific aspects of AN. Research using the ABA paradigm to probe the role of hedonic and homeostatic circuits has indicated that the hypothalamic proopiomelanocortin (POMC) system may play a role in both the increased activity and reduced food intake observed. Previous work has shown that Pomc mRNA and its peptide product beta‐endorphin (β‐end) are increased during the onset of ABA. β‐end is reinforcing and increases locomotor activity, and mice lacking the mu opioid receptor (MOR), the primary target of β‐end, display blunted food‐anticipatory activity in the ABA paradigm. Thus, the current work was designed to determine if aspects of ABA would be diminished in mice lacking β‐end. We did not find any significant differences in wheel‐running, food intake, or body weight loss in β‐end knockout mice of either sex during ABA compared to wild‐type littermates. Therefore, we conclude that the development of ABA does not require β‐end.
Fabric pattern recognition using image processing and AHP method
Authors: Al Saleh Manal , Hamdi Thouraya , Jmali Mohamed 
Published: February 2025

Abstract
This article aims to provide methods and a system to recognize the woven fabric patterns automatically. Two different approaches were designed to identify the woven patterns in this article: image analysis and the analytic hierarchy process (AHP). In this work, identifying the woven fabric patterns is based on the measurement of some characteristics and parameters that clearly describe and explain the contexture of the fabric. The methods used were essentially pattern recognition and image processing, which aim to numerically calculate four critical parameters which can give a clear idea of the texture and the patterns of fabrics: the continuity of diagonal lines, the section succession in the vertical direction, section succession in the horizontal direction, and isolated blocks. Then, we used the AHP to classify basic weave patterns into three classes representing the fundamental weaves: plain, twill, and satin. Finally, the statistical approach used to evaluate the efficiency of the proposed method concerning classification showed high correlation values between the predicted results and the experimental values. This study has practical implications in the textile industry, especially in the clothing sector. The manufacturers can use the results to automatically identify the woven fabric patterns without using the manual examination method.
Desinformation auf der Spur: Konzept einer Bibliotheksschulung
Authors: Umlauft Valentin 
Published: February 2025

Zusammenfassung
Die anhaltende Desinformationskrise stellt eine massive Gefahr für unsere Gesellschaft dar. Bibliotheken steuern mit Schulungsformaten und Lernressourcen praktische Gegenmaßnahmen bei. Zur Wirksamkeit müssen Angebote allerdings einheitliche Begrifflichkeiten sowie Konzepte zu Mechanismen und Wirkung von Informationsstörungen umfassen, aktuelle technische Trends und Forschungsergebnisse berücksichtigen und praxistaugliche Recherche- und Evaluierungswerkzeuge beinhalten. Vor diesem Hintergrund präsentiert der Artikel ein niederschwelliges Angebotsformat für Bibliotheksnutzende.