bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effect of Microwave Heating on Ullmann‐Type Heterocycle‐Aryl Ether Synthesis Using Chloro‐Heterocycles.
Authors: D'Angelo Noel D. , Peterson Joseph J. , Booker Shon K. , Fellows Ingrid , Dominguez Celia , Hungate Randall , Reider Paul J. , Kim Tae‐Seong 
Published: October 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Antiproliferative Effect of Baylis—Hillman Adducts and a New Phthalide Derivative on Human Tumor Cell Lines.
Authors: Kohn Luciana K. , Pavam C. H. , Veronese D. , Coelho F. , De Carvalho J. E. , Almeida Wanda P. 
Published: October 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Design, Synthesis and in vivo Anticonvulsant Screening in Mice of Novel Phenylacetamides.
Authors: Shindikar A. V. , Khan F. , Viswanathan C. L. 
Published: October 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Control of Four Stereocenters in a Triple Cascade Organocatalytic Reaction.
Authors: Enders Dieter , Huettl Matthias R. M. , Grondal Christoph , Raabe Gerhard 
Published: October 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Proline‐Catalyzed Diastereoselective Direct Aldol Reaction Between 4‐Oxoazetidine‐2‐carbaldehydes and Ketones.
Authors: Alcaide Benito , Almendros Pedro , Luna Amparo , Torres M. Rosario 
Published: October 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Synthesis of 5‐Mercapto‐1,2‐dithiole‐3‐thiones and Their Transformation into 5‐Chloro‐1,2‐dithiol‐3‐ones.
Authors: Konstantinova L. S. , Berezin A. A. , Lysov K. A. , Rakitin O. A. 
Published: October 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
A Mild, One‐Pot Synthesis of Disubstituted Benzimidazoles from 2‐Nitroanilines.
Authors: Hornberger Keith R. , Adjabeng George M. , Dickson Hamilton D. , Davis‐Ward Ronda G. 
Published: October 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
New, Diastereoselective One‐Pot Synthesis of Tetrasubstituted Hydantoins (IV)/(V).
Authors: Alizadeh Abdolali , Masrouri Hassan 
Published: October 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Reaction of Polyhaloalkyl‐Substituted Chromones, Pyrones and Furanones with Salicylaldehydes as a Direct Route to Fused 2H‐Chromenes.
Authors: Sosnovskikh Vyacheslav Ya. , Korotaev Vladislav Yu. , Chizhov Dmitry L. , Kutyashev Igor B. , Yachevskii Danil S. , Kazheva Olga N. , Dyachenko Oleg A. , Charushin Valery N. 
Published: October 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Synthesis of gem‐Difluoromethylenated Daidzein Analogues and Their Inhibitory Effect on U2OS Cell Cycle.
Authors: Meng Wei‐Dong , Zhang Zhi‐Hang , Qing Feng‐Ling , Li Qing , Zhang Yue‐Yue , Wang Hui‐Sheng 
Published: October 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Synthesis of Unsymmetrically 2,6‐Disubstituted 2,3‐Dihydrothiopyran‐4‐ones.
Authors: Rosiak Anna , Christoffers Jens 
Published: October 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Selective 6‐endo Cyclization of the Acyl Radicals onto the Nitrogen of Imine and Oxazoline C—N Bonds.
Authors: Tojino Mami , Otsuka Noboru , Fukuyama Takahide , Matsubara Hiroshi , Ryu Ilhyong 
Published: October 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Synthesis of Substituted 5‐Aminomethyl Tetrahydro‐Isoquinolines (VI) and Dihydro‐Isoindoles (XII).
Authors: Fray M. Jonathan , et al. et al. 
Published: October 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Preparation of 2,3‐Dihydro‐1H‐spiro[isoquinoline‐4,4′‐piperidine] via an N‐Sulfonyl Pictet—Spengler Reaction.
Authors: Liu Jian , Jian Tianying , Sebhat Iyassu , Nargund Ravi 
Published: October 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Microwave‐Assisted One‐Pot U‐4CR and Intramolecular O‐Alkylation Toward Heterocyclic Scaffolds.
Authors: Xing Xinglong , Wu Jinlong , Feng Gaofeng , Dai Wei‐Min 
Published: October 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Synthesis of 1,3,5‐Thiadiazines from Formamidinothiocarbamide.
Authors: Tayade D. T. , Shelke M. E. , Wagmare J. S. , Panpaliya R. C. 
Published: October 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Synthesis and Antiproliferative Activities of Indolin‐2‐one Derivatives Bearing Amino Acid Moieties.
Authors: Sassatelli Mathieu , Debiton Eric , Aboab Bettina , Prudhomme Michelle , Moreau Pascale 
Published: October 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Operationally Convenient Asymmetric Synthesis of (S)‐ and (R)‐3‐Amino‐4,4,4‐trifluorobutanoic Acid. Part 2. Enantioselective Biomimetic Transamination of 4,4,4‐Trifluoro‐3‐oxo‐N‐[(R)‐1‐phenylethyl]butanamide.
Authors: Soloshonok Vadim A. , Ohkura Hironari , Yasumoto Manabu 
Published: October 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Synthesis of 2′,3′‐Dideoxynucleosides via C—S Bond Cleavage: N‐Glycosylation of 2,3‐Dideoxy‐1‐[(2‐pyridylmethyl)thio]glycoside.
Authors: Mitsudo Koichi , Matsuda Wataru , Miyahara Seiji , Tanaka Hideo 
Published: October 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Fine Chemicals by Reductive Carbonylation of Nitroarenes, Catalyzed by Transition‐Metal Complexes
Authors: Ragaini Fabio , Cenini Sergio , Gallo Emma , Caselli Alessandro , Fantauzzi Simone 
Published: October 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Chiral Ureas and Thioureas in Asymmetric Catalysis
Authors: Breuzard Jeremy A. J. , Christ‐Tommasino M. Lorraine , Lemaire Marc 
Published: October 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Solid‐Phase Synthesis of Quinazoline‐2,4‐diones and Their Analogues from Resin‐Bound Compounds with Primary Amines
Authors: Makino Shingo 
Published: October 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
A MEMS GC‐Mini‐cell IMS for Astrobiology Measurements
Authors: Stimac Robert M. , Kaye William J. , Holland Paul M. , Kojiro Daniel R. , Takeuchi Norishige 
Published: October 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Complications of combined modality treatment of primary lower extremity soft‐tissue sarcomas
Authors: Cannon Christopher P. , Ballo Matthew T. , Zagars Gunar K. , Mirza Attiqa N. , Lin Patrick P. , Lewis Valerae O. , Yasko Alan W. , Benjamin Robert S. , Pisters Peter W.T. 
Published: October 2006

AbstractBACKGROUND.Correlations between various patient, tumor, and treatment characteristics and complications in patients undergoing combined modality treatment for primary lower extremity soft‐tissue sarcomas were investigated.METHODS.Using the M. D. Anderson Radiation Oncology database, the records of the subset of patients treated with combined radiation and limb‐sparing surgery for primary lower extremity soft‐tissue sarcomas were retrospectively reviewed from the years 1960 to 2003.RESULTS.In all, 412 patients were identified. With a median follow‐up of 9.3 years, there were a total of 113 (27%) acute wound complications and 41 (13% at 20 years) chronic radiation‐related limb complications. Preoperative radiation and tumor sizes >5 cm were associated with an increased risk of acute wound complications (34% preoperative vs. 16% postoperative, P < .001; and 31% >5 cm vs. 17% ≤5 cm, P = .005). At 20 years the radiation‐related complication rate was higher in patients with a groin or thigh tumor location (16% vs. 4% other; P = .008), prior acute wound complications (20% vs. 10% no surgical complication), and a radiation dose ≥60 grays (Gy) (18% vs. 9% for dose < 60 Gy; P = .04). Five fractures occurred, resulting in a crude overall fracture rate of 1.2%.CONCLUSIONS.Patients treated with preoperative radiation for larger tumors are more likely to have acute surgical wound complications. Acute wound complications followed by postoperative radiation are associated with chronic radiation‐related limb problems, as are higher radiation dose and proximal tumor location. The fracture rate is so low that prophylactic fixation is not warranted. Cancer 2006. © 2006 American Cancer Society.
Proposal of SDMA configuration adopting directivity and polarization control
Authors: Komiya Kazuhiro , Nishimori Kentaro , Cho Keizo , Hori Toshikazu 
Published: October 2006

AbstractIn this paper, a new SDMA (Space Division Multiple Access) configuration is proposed in which the number of multitudes of SDMA can be increased by using dual polarization antennas at both the smart antenna base stations and the mobile terminals. In the proposed configuration, the smart antennas at the base stations constantly monitor the mutual correlations between the mobile terminals at the time of reception. Then, the polarization (vertical or horizontal) to be transmitted by each mobile terminal is determined in such a way that the mutual correlation between the mobile terminals connected at the same time is minimized. The mobile terminal used in the proposed system has a configuration in which the antennas with vertical and horizontal polarizations can be switched for transmission. Transmission is carried out with the polarization specified by the base station. The proposed configuration is expected not only to improve spatial division capability of SDMA by the smart antenna base station with vertical and horizontal polarizations but also to compensate the deterioration of the transmission quality along with the increase of multiplicity of SDMA by means of the switching configuration of the transmission polarization of the mobile terminal while the interference between the mobile terminals is taken into account. The proposed configuration can be applied to the uplinks in the TDD or FDD channels. By means of the numerical simulation, the basic characteristics of the proposed configuration are clarified in the case where the cross polarization discrimination (XPD) and the number of mobile terminals vary. In this way, it is demonstrated that the mobile terminal discrimination capability is improved over the conventional SDMA with the vertical polarization and the system is useful for increased multiplicity of SDMA. Further, the propagation characteristics (amplitude and phase) of the vertical and horizontal polarizations are obtained when the base station antenna and the mobile terminal antenna are placed on a steel tower and on a vehicle, respectively. The characteristics of the proposed configuration are presented where several mobile terminals exist. Usefulness of the proposed configuration in an actual environment for increased multiplicity of SDMA is presented. © 2006 Wiley Periodicals, Inc. Electron Comm Jpn Pt 1, 90(2): 33–45, 2007; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/ecja.20287
Effect of contact angle on wetting limit temperature
Authors: Hidaka Sumitomo , Yamashita Akimitsu , Takata Yasuyuki 
Published: October 2006

AbstractThe effect of surface wettability on evaporation of a water drop has been examined experimentally using surfaces with various contact angles. To greatly change the surface wettability, TiO2 superhydrophilicity, plasma irradiation, and super‐water‐repellent surface are adopted as the heating surface. The range in contact angle achieved by these methods was between 0° and 170°. The relationship between the contact angle and the wetting limit temperature was obtained and it was found that the lifetime of a water drop dramatically decreases with contact angle in the lower temperature region, and that the wetting limit temperature increases with the contact angle. © 2006 Wiley Periodicals, Inc. Heat Trans Asian Res, 35(7): 513–526, 2006; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/htj.20128
Unbalanced expression of licensing DNA replication factors occurs in a subset of mantle cell lymphomas with genomic instability
Authors: Pinyol Magda , Salaverria Itziar , Bea Silvia , Fernández Verónica , Colomo Lluís , Campo Elías , Jares Pedro 
Published: October 2006

AbstractDNA licensing is a crucial process for chromosome replication control. Deregulation of the licensing factors Cdt1, Cdc6 and the licensing inhibitor geminin has been associated with DNA replication defects and chromosomal instability. We examined the expression of these factors, in mantle cell lymphoma (MCL) and non‐neoplastic lymphoid samples, and analysed the potential role of their deregulation in genomic instability. Geminin, Cdt1 and Cdc6 were coordinately expressed in non‐neoplastic tissues and most MCL in relationship to the proliferative activity of the cells. However, 6 (18%) tumours showed an unbalanced “licensing signature” characterized by a higher expression of Cdt1 and Cdc6 than the negative regulator geminin. Tumours with this unbalanced signature and p53/p14ARF alterations had significantly higher number of chromosome abnormalities than lymphomas with p53/p14ARF alterations but with a normal licensing signature. No aberrations of Cdct1, Cdc6, and geminin genes were detected in cases with unbalanced licensing. However, tumours with p53/ARF inactivation and unbalanced licensing signature had significantly higher cyclin D1 levels than tumours with normal licensing signature. These results suggest that an unbalanced mRNA expression of licensing regulatory genes may play a role in the pathogenesis of the chromosomal instability of a subset of MCL with inactivation of the p53/p14ARF pathway. © 2006 Wiley‐Liss, Inc.
An interferon‐sensitive response element is involved in constitutive caspase‐8 gene expression in neuroblastoma cells
Authors: De Ambrosis Alessandro , Casciano Ida , Croce Michela , Pagnan Gabriella , Radic Luana , Banelli Barbara , Di Vinci Angela , Allemanni Giorgio , Tonini Gian Paolo , Ponzoni Mirco , Romani Massimo , Ferrini Silvano 
Published: October 2006

AbstractWe previously identified a 1.2 Kb DNA element (P‐1161/+16), 5′ to caspase‐8 exon‐1, that acts as promoter in caspase‐8‐positive, but not in caspase‐8‐negative neuroblastoma (NB) cells. The P‐1161/+16 DNA element regulates both constitutive and interferon IFN‐γ‐inducible caspase‐8 expression. Two GAS (IFN‐activated sequence, STAT‐1 binding site) and two ISRE (interferon sensitive response element, IRF binding site) were present in P‐1161/+16. Deletion studies indicated that elements essential for promoter activity in NB cells were present in a 167 bp region 5′ flanking exon‐1 (P‐151/+16), which contains an ISRE at position −32. The transcription initiation site was mapped by 5′ rapid amplification of cDNA end (RACE) at position −20 from caspase‐8 cDNA reference sequence. Disruption of the ISRE‐32 indicated that it is required for both constitutive and IFN‐γ‐inducible caspase‐8 expression. IRF‐1 and IRF‐2 transcription factors bind to the (−151/+16) DNA fragment in vitro. Chromatin immunoprecipitation (ChIP) assays showed that IRF‐1 and IRF‐2 bind to the DNA region at the 5′ of caspase‐8 gene in NB cells, which show constitutive expression but not in caspase‐8 negative cells. In these last cells, up‐regulation of caspase‐8 by IFN‐γ was associated to induction of IRF‐1 and IRF‐2 binding to caspase‐8 promoter and increased histone acetylation. Moreover, RNA interference experiments also supported the involvement of IRF‐1 and IRF‐2 in constitutive caspase‐8 expression in NB cells. © 2006 Wiley‐Liss, Inc.
Seasonal Variability of Particulate Organic Matter in a Mountain Stream in Central Spain
Authors: Mollá Salvador , Robles Santiago , Casado Carmen 
Published: October 2006

AbstractThe aim of this paper was to study the influence of environmental characteristics of the Mediterranean climate on seasonal variability of particulate organic matter abundance in a mountain stream. Coarse and fine fractions of both suspended and benthic particulate organic matter were determined on 14 occasions between February 1998 and November 1999 in a second‐order Mediterranean stream in Central Spain (Arroyo Mediano). Temporal variability of suspended organic matter followed a seasonal pattern, attributed to litter‐fall inputs, instream processing, and the hydrological regime. Suspended organic matter (SOM) and its seasonal variability fall well within the range reported for streams in temperate non‐Mediterranean deciduous forest. However, we found no seasonal trend in benthic organic matter (BOM) storage, and it seems that the amount of BOM remained fairly constant throughout the year. Reach retention (evaluated as the ratio between BOM and SOM per m2) was higher in summer during reduced stream flow, mainly due to coarse particulate organic matter storage. These observations do not differ from those reported for other headwater streams in temperate forested biomes, from which we conclude that there was no evidence of a Mediterranean influence on particulate organic matter dynamics in the Mediano stream, nor probably in other headwater Mediterranean streams. (© 2006 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
Myocardial perfusion
Authors: Schwitter Juerg 
Published: October 2006

AbstractNoninvasive cardiac magnetic resonance (CMR) imaging has progressed rapidly over the past few years and will most likely become an integral part of the diagnostic workup of patients with known or suspected coronary artery disease (CAD). In this article the rationale for using perfusion‐CMR is discussed, followed by a summary of current state‐of‐the‐art perfusion‐CMR techniques that addresses pharmacological stress, monitoring, pulse sequences, and doses of contrast media (CM) for first‐pass studies. In the second part, unresolved aspects of perfusion‐CMR, such as the lack of fully established and validated imaging protocols, are discussed. The optimum pulse sequence parameters, required cardiac coverage, analysis algorithms, criteria for data quality, and other aspects remain to be defined. Furthermore, since expertise in perfusion‐CMR is not yet widely available, training of physicians and technicians to perform perfusion‐CMR according to recognized standards is an important future requirement. In the last part of the review, some ideas are proposed to improve the management of patients with known or suspected CAD. This involves making a shift from a “reactive” strategy, in which patients are typically approached when they are symptomatic, to an “active” strategy, in which perfusion‐CMR is performed for early detection of high‐risk patients so that revascularizations can be performed before potentially deadly infarcts occur. An ideal test for such an active strategy would be highly accurate, reliable, safe (and thus repeatable), and affordable. Large multicenter trials have shown that in experienced centers perfusion‐CMR is reliable and repeatable, and it is hoped that future studies will demonstrate its cost‐effectiveness as well. J. Magn. Reson. Imaging 2006. © 2006 Wiley‐Liss, Inc.
Novel epididymis‐specific mRNAs downregulated by HE6/Gpr64 receptor gene disruption
Authors: Davies Ben , Behnen Martina , Cappallo‐Obermann Heike , Spiess Andrej‐Nikolai , Theuring Franz , Kirchhoff Christiane 
Published: October 2006

AbstractTargeted disruption of the epididymis‐specific HE6/Gpr64 receptor gene in mice led to male infertility. In order to characterize the phenotype at a molecular level, we compared the gene expression patterns of wild type (wt) versus knockout (KO) caput epididymides. The caput region of KO males, although morphologically normal, nevertheless showed an aberrant expression pattern. Combining micro array analysis, differential library screening, Northern blot analysis and quantitative RT‐PCR, we found that the knockout of the HE6/Gpr64 receptor was mainly associated with the downregulation of genes specific to the initial segment. The list of KO downregulated transcripts comprised Enpp2/autotaxin, the lipocalins 8 and 9, the β‐defensin Defb42, cystatins 8 and 12, as well as the membrane proteins Adam (A Disintegrin And Metalloprotease) 28, claudin‐10, EAAC1, and the novel Me9. Clusterin/ApoJ and osteopontin/Spp1 mRNAs, on the other hand, were upregulated in the KO tissues. The Me9 transcript was studied in further detail, and we report here a cluster of related epididymis‐specific genes. Me9 is specifically expressed in the initial segment and is representative of a novel and highly conserved mammalian gene family. The family consists of single‐exon genes only; intron‐containing paralogs have not yet been ascertained. The cloned cDNA sequences predicted hydrophobic polytopic membrane proteins containing the DUF716 motif. Protein expression was shown in the rodent caput epididymidis but remained uncertain in primates. Mol. Reprod. Dev. 74: 539–553, 2007. © 2006 Wiley‐Liss, Inc.