bluuebunny/crossref_metadata_2025_split huggingface dataset:
A preliminary investigation of the concurrent validity of reading comprehension rate: A direct, dynamic measure of reading comprehension
Authors: Neddenriep Christine E. , Hale Andrea D. , Skinner Christopher H. , Hawkins Renee O. , Winn Beth D. 
Published: March 2007

AbstractReading comprehension rate (RCR) is a direct measure of reading skills that may be useful in formatively evaluating students reading beyond the fourth‐grade level. To investigate the concurrent validity of RCR, we correlated RCR, reading comprehension level (RCL), and words correct per minute (WC/M) with the Broad Reading Cluster Scores of the Woodcock‐Johnson III Tests of Achievement (WJ‐III ACH) across 88 students in 4th, 5th, and 10th grades. Results showed that aloud‐RCR was significantly correlated with the WJ‐III ACH scores for 4th‐grade (r = .90; n = 22), 5th‐grade (r = .87; n = 29), and 10th‐grade (r = .65; n = 37) students. Regression analysis specified a one‐predictor model for 4th‐grade students (aloud‐RCR), a two‐predictor model for 5th‐grade students (WC/M and aloud‐RCR), and a one‐predictor model for 10th‐grade students (WC/M). Discussion focuses on directions for future research and applied issues related to RCR probe passage development. © 2007 Wiley Periodicals, Inc. Psychol Schs 44: 373–388, 2007.
Culturally competent interventions in schools for children with physical health problems
Authors: Clay Daniel L. 
Published: March 2007

AbstractAn estimated 5.2 to 7.8 million children with significant chronic health problems attend school every day in the United States requiring interventions in the school setting. A majority of these students will be from ethnic minority or low‐income groups within two decades. Providing culturally competent interventions in schools is critical to optimize the health, educational, and psychological outcomes of children with significant health problems. This article underscores the culture and health connection and presents a 5‐step model for providing culturally competent services for health problems in schools. The article is intended to help school personnel to determine if, when, and how to incorporate cultural issues in assessment, treatment planning, and intervention. © 2007 Wiley Periodicals, Inc. Psychol Schs 44: 389–396, 2007.
Promoting social and academic competence in the classroom: An intervention study examining the contribution of the Responsive Classroom approach
Authors: Rimm‐Kaufman Sara E. , Chiu Yu‐Jen I. 
Published: March 2007

AbstractThis exploratory study examined the contribution of the RC Approach over a two‐year period. The RC Approach integrates social and academic learning in order to produce classroom environments that are conducive to learning by integrating social and academic learning. Two questions are addressed. First, how does teachers' use of RC practices contribute to children's academic and social growth? Second, how is the relation between teachers' use of RC practices and children's academic and social growth moderated by the presence of environmental adversity in the home? Participants included 62 teachers and 157 children at six schools. Findings showed that teachers' use of RC practices was associated with students' improved reading achievement, greater closeness between teachers and children, better pro‐social skills, more assertiveness, and less fearfulness, even after controlling for family risk and children's previous years' performance. Family risk did not moderate the relation between RC practices and children's performance. These findings suggest to the positive contribution of the RC Approach in relation to children's gains over a one‐year period. © 2007 Wiley Periodicals, Inc. Psychol Schs 44: 397–413, 2007.
Beyond reductionism: Metabolic circularity as a guiding vision for a real biology of systems
Authors: Cornish‐Bowden Athel , Cárdenas María Luz , Letelier Juan‐Carlos , Soto‐Andrade Jorge 
Published: March 2007

AbstractThe definition of life has excited little interest among molecular biologists during the past half‐century, and the enormous development in biology during that time has been largely based on an analytical approach in which all biological entities are studied in terms of their components, the process being extended to greater and greater detail without limit. The benefits of this reductionism are so obvious that they need no discussion, but there have been costs as well, and future advances, for example, for creating artificial life or for taking biotechnology beyond the level of tinkering, will need more serious attention to be given to the question of what makes a living organism living. According to Robert Rosen's theory of metabolism‐replacement systems, the central idea missing from molecular biology is that of metabolic circularity, most evident from the obvious but commonly ignored fact that proteins are not given from outside but are products of metabolism, and thus metabolites. Among other consequences, this implies that the usual distinction between proteome and metabolome is conceptually artificial – however useful it may be in practice – as the proteome is part of the metabolome.
A review of standards for data exchange within systems biology
Authors: Strömbäck Lena , Hall David , Lambrix Patrick 
Published: March 2007

AbstractThe rapid increase in experimental data within systems biology has increased the need for exchange of data to allow analysis and comparison of larger datasets. This has resulted in a need for standardized formats for representation of such results and currently many formats for representation of data have been developed or are under development. In this paper, we give an overview of the current state of available standards and ontologies within systems biology. We focus on XML‐based standards for exchange of data and give a thorough description of similarities and differences of currently available formats. For each of these, we discuss how the important concepts such as substances, interactions, and experimental data can be represented. In particular, we note that the purpose of a standard is often visible in the structures it provides for the representation of data. A clear purpose is also crucial for the success of a standard. Moreover, we note that the development of representation formats is parallel to the development of ontologies and the recent trend is that representation formats make more and more use of available ontologies.
Prediction of nitrogen metabolism‐related genes in Anabaena by kernel‐based network analysis
Authors: Okamoto Shinobu , Yamanishi Yoshihiro , Ehira Shigeki , Kawashima Shuichi , Tonomura Koichiro , Kanehisa Minoru 
Published: March 2007

AbstractPrediction of molecular interaction networks from large‐scale datasets in genomics and other omics experiments is an important task in terms of both developing bioinformatics methods and solving biological problems. We have applied a kernel‐based network inference method for extracting functionally related genes to the response of nitrogen deprivation in cyanobacteria Anabaena sp. PCC 7120 integrating three heterogeneous datasets: microarray data, phylogenetic profiles, and gene orders on the chromosome. We obtained 1348 predicted genes that are somehow related to known genes in the Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways. While this dataset contained previously known genes related to the nitrogen deprivation condition, it also contained additional genes. Thus, we attempted to select any relevant genes using the constraints of Pfam domains and NtcA‐binding sites. We found candidates of nitrogen metabolism‐related genes, which are depicted as extensions of existing KEGG pathways. The prediction of functional relationships between proteins rather than functions of individual proteins will thus assist the discovery from the large‐scale datasets.
From proteomics to systems biology of bacterial pathogens: Approaches, tools, and applications
Authors: Plikat Uwe , Voshol Hans , Dangendorf Yvonne , Wiedmann Brigitte , Devay Piroska , Müller Dieter , Wirth Urs , Szustakowski Joseph , Chirn Gung‐Wei , Inverardi Bruno , Puyang Xiaoling , Brown Kara , Kamp Heather , Hoving Sjouke , Ruchti Alexandra , Brendlen Nathalie , Peterson Ron , Buco Jennifer , Oostrum Jan van , Peitsch Manuel C. 
Published: March 2007

AbstractThe hallmark of a systems biology approach is the integration of computational tools with experimental data encompassing multiple classes of biomolecules across different functional levels. Equally important as the availability of reasonably comprehensive information at the gene, protein, and metabolite levels is the development of adequate analysis and visualization tools to reduce the inherent complexity to interpretable dimensions. In this paper, we describe the integration of a 2‐D gel‐based proteome map of Staphylococcus aureus Mu50 with genomic and transcriptomic information through a customized data integration and user interface built on the Ensembl genome browser. We illustrate its application and potential through the analysis of a defined system perturbation caused by a mutation in the formyltransferase gene. We envision that this software package, which we called Insieme, can support the development of novel antibiotics by allowing a systems‐based view of the bacterial response pathways.
Who wants to be an ICH Euro billionaire?
Authors: Gordon Kerry 
Published: March 2007

AbstractThe ICH E9 guideline on Statistical Principles for Clinical Trials is a pivotal document for statisticians in clinical research in the pharmaceutical industry guiding, as it does, statistical aspects of the planning, conduct and analysis of regulatory clinical trials. New statisticians joining the industry require a thorough and lasting understanding of the 39‐page guideline. Given the amount of detail to be covered, traditional (lecture‐style) training methods are largely ineffective. Directed reading, perhaps in groups, may be a helpful approach, especially if experienced staff are involved in the discussions. However, as in many training scenarios, exercise‐based training is often the most effective approach to learning. In this paper, we describe several variants of a training module in ICH E9 for new statisticians, combining directed reading with a game‐based exercise, which have proved to be highly effective and enjoyable for course participants. Copyright © 2007 John Wiley & Sons, Ltd.
Table of Feynman diagrams of the interacting Fermion Green's function
Authors: Mathar Richard J. 
Published: March 2007

AbstractThe Feynman diagrams of the Green's function expansion of fermions interacting with a nonrelativistic 2‐body interaction are displayed in first, second, and third perturbative order of the interaction as 2, 10, and 74 diagrams, respectively. A name convention for the diagrams is proposed and then used to tabulate the diagrams of fourth to seventh order. The Hartree–Fock approximation summons up 2, 8, 40, and 224 of them in first through fourth order. © 2007 Wiley Periodicals, Inc. Int J Quantum Chem, 2007
Liquid chromatography/electrospray ionization tandem mass spectrometry profiling of compounds from the infusion of Byrsonima fagifolia Niedenzu
Authors: Sannomiya Miriam , dos Santos Lourdes Campaner , Carbone Virginia , Napolitano Assunta , Piacente Sonia , Pizza Cosimo , Souza‐Brito Alba R. M. , Vilegas Wagner 
Published: March 2007

AbstractA rapid analytical approach suitable to achieve a comprehensive characterization of the compounds present in the infusion prepared from the leaves of Byrsonima fagifolia Niedenzu (Malpighiaceae), a Brazilian plant used as an infusion to treat gastric disorders, was developed. The method was based on high‐performance liquid chromatography coupled to electrospray negative ionisation multistage ion trap mass spectrometry (HPLC/ESI‐ITMSn).The main ions in the ESI‐ITMS spectra were attributed to a quinic acid core containing from one to five galloyl units. Quercetin derivatives containing one and two sugar moieties as well as galloyl esterification were also detected. These results indicated that HPLC/ESI‐ITMSn is easily applicable to infusions of this plant and allows the rapid and direct identification of these compounds in crude plant extracts. Copyright © 2007 John Wiley & Sons, Ltd.
The moderating influence of firm market power on the transaction cost economics model: An empirical test in a forward channel integration context
Authors: Shervani Tasadduq A. , Frazier Gary , Challagalla Goutam 
Published: March 2007

AbstractTransaction cost economics (TCE) has guided a variety of research on governance in the strategic management literature. An important question arises, however, as to whether the TCE framework is equally appropriate for all types of firms in all business settings. In this paper, we argue that TCE is not and suggest that firms with high market power may be able to lower transaction costs under high asset specificity and uncertainty in nonintegrated distribution channels, avoiding the need to utilize highly integrated channels as a result. We test our hypotheses with data collected from 40 manufacturers of electronic and telecommunications products in 109 product‐markets in the United States. The results support our hypothesis that transaction cost factors are better at explaining forward channel integration for firms with low market power than for firms with high market power. Our results indicate that the basic TCE framework must be supplemented by the market power construct to adequately explain forward channel integration decisions. Copyright © 2007 John Wiley & Sons, Ltd.
Building firm capabilities through learning: the role of the alliance learning process in alliance capability and firm‐level alliance success
Authors: Kale Prashant , Singh Harbir 
Published: March 2007

AbstractIn recent years, academics and managers have been very interested in understanding how firms develop alliance capability and have greater alliance success. In this paper, we show that an alliance learning process that involves articulation, codification, sharing, and internalization of alliance management know‐how is positively related to a firm's overall alliance success. Prior research has found that firms with a dedicated alliance function, which oversees and coordinates a firm's overall alliance activity, have greater alliance success. In this paper we suggest that such an alliance function is also positively related to a firm's alliance learning process, and that process partly mediates the relationship between the alliance function and alliance success observed in prior work. This implies that the alliance learning process acts as one of the main mechanisms through which the alliance function leads to greater alliance success. Our paper extends prior alliance research by taking a first step in opening up the ‘black box’ between the alliance function and a firm's alliance success. We use survey data from a large sample of U.S.‐based firms and their alliances to test our theoretical arguments. Although we only examine the alliance learning process and its relationship with firm‐level alliance success, we also make an important contribution to research on the knowledge‐based view of the firm and dynamic capabilities of firms in general by conceptualizing this learning process and its key aspects, and by empirically validating its impact on performance. Copyright © 2007 John Wiley & Sons, Ltd.
Modeling service alliances: an exploratory investigation of spillover effects in service partnerships
Authors: Bourdeau Brian L. , Cronin Jr J. Joseph , Voorhees Clay M. 
Published: March 2007

AbstractThe objective of the current study is to provide a preliminary look at the process by which consumers evaluate alliances between service providers. Specifically, the study demonstrates how the service quality of one partner can impact, or ‘spill over’ onto, consumers' evaluations of their transactions with a second partner, and how the performances of partners can have differing effects on customers' intentions to reuse a service partnership. The study tests hypotheses related to the quality, value, and reuse intentions of customers relative to the partnered service through a sample of 334 customers utilizing a seamless service alliance. Our results suggest that spillover effects of service partnerships can either result in beneficial gains for service partners or produce grave consequences when partner providers' service quality is substandard. Copyright © 2007 John Wiley & Sons, Ltd.
International diversification, subsidiary performance, and the mobility of knowledge resources
Authors: Fang Yulin , Wade Michael , Delios Andrew , Beamish Paul W. 
Published: March 2007

AbstractWe examine the link between international diversification, organizational knowledge resources, and subsidiary performance. The success of international corporate diversification depends on a firm's capability to transfer knowledge to its subsidiaries, and how its local subsidiaries effectively utilize that knowledge. As knowledge resources are imperfectly mobile, a firm may find it difficult to transfer knowledge to its subsidiaries. In our analysis of 4964 Japanese subsidiaries over a 14‐year period, we find that knowledge that is valuable, but not rare, positively affects subsidiary performance in the short term, but not the long term. In contrast, knowledge that is both valuable and rare affects subsidiary performance in the long term, but not the short term. Copyright © 2007 John Wiley & Sons, Ltd.
Self‐Assembled Single‐ and Double‐Stack π‐Aggregates of Chlorophyll Derivatives on Highly Ordered Pyrolytic Graphite
Authors: Huber Valerie , Lysetska Marina , Würthner Frank 
Published: March 2007

AbstractThe highly efficient, light‐harvesting antennae systems present in chlorosomes of green phototrophic bacteria, such as Chloroflexus aurantiacus, serve as a model for the design of bioinspired nanostructured materials. A semisynthetic zinc chlorin, derived from natural chlorophyll a, is used as a building block that self‐assembles into excitonically coupled chromophore stacks. Temperature‐dependent UV/Vis and circular dichroism spectroscopic measurements show the reversible formation of soluble chiral aggregates of this new zinc chlorin dye. High‐resolution scanning tunneling microscopy and atomic force microscopy studies reveal the formation of two types of well‐ordered π‐stacked aggregates on highly ordered pyrolytic graphite.
Acyl Migration Kinetics of 2‐Monoacylglycerols from Soybean Oil via 1H NMR
Authors: Compton David L. , Vermillion Karl E. , Laszlo Joseph A. 
Published: March 2007

AbstractThe acyl migration kinetics of neat 2‐monoacylglycerol (2‐MAG) to form 1‐MAG was determined using 1H NMR spectroscopy to monitor the β‐proton integration ratios of the two species over time. 2‐MAG was synthesized by the Novozym 435‐catalyzed alcoholysis of soybean oil and isolated by solvent extraction or molecular distillation at a mole fraction (X2‐MAG) of 0.94 relative to total MAG. The kinetics parameters of the neat 2‐MAG acyl migration were investigated over the temperature range of 23–80 °C. The 2‐MAG mol fraction remained unchanged at 23 °C over the course of 168 h and reached an equilibrium of X2‐MAG = 0.09 at only 80 °C. Modeling of the kinetics data revealed a 2‐MAG half life (t1/2) of 3,500 and 22.8 h at 23 and 80 °C, respectively, with an activation energy of 79.0 ± 6.5 kJ mol−1. The use of 1H NMR spectroscopy proved an expedient method for monitoring the acyl migration in 2‐MAG compared to other reported methods (e.g. GC, HPLC, and 13C‐NMR spectroscopy), requiring no sample manipulation and minimizing the deleterious effects of high temperatures and solvent exposure.
Flooding induces secondary dormancy in Setaria parviflora seeds
Authors: Mollard Federico P.O. , Insausti Pedro , Sánchez Rodolfo A. 
Published: March 2007

AbstractThe effect of flooding on the dormancy level of Setaria parviflora seeds from a non-flooded upland and a seasonally (winter–spring) flooded lowland in the Pampa grasslands of Argentina was investigated. Seeds from both communities were subjected to reciprocal burial treatments in the two habitats, and exhumed during and after the flooding season. Effect of immersion in water at 5°C was compared to incubation of seeds on the surface of water-saturated paper at the same temperature. After exhumation of the buried seeds or immersion treatments, germination was assayed at 25°C and at 20/30°C in the dark or in combination with light. Burial in the lowland, which was flooded in winter–spring, significantly reduced germination, while burial in the non-flooded upland did not reduce germination. Similarly, immersion in water at 5°C significantly reduced germination compared to non-immersed controls. During summer, seeds buried in the lowland showed increased capacity to germinate, particularly when exposed to fluctuating temperatures or light. Thus, flooding induced secondary dormancy in S. parviflora seeds, and it was broken during the non-flooding season. These responses of the seeds would prevent germination until there was no further risk of flooding. Remarkably, in S. parviflora seeds harvested from both habitats, we observed essentially the same germination requirements after flooding. However, some slight differences were detected between the seed populations exhumed from the lowland site, indicating that flooding had larger effects on the seeds from the upland community. This suggests some differentiation of these populations evident only after flooding in the field.
Expression and characterization of human growth hormone–Fc fusion proteins for transcytosis induction
Authors: Lee Chang Hoon , Woo Jung Hee , Cho Kwang Keun , Kang Seung Ha , Kang Sang Kee , Choi Yun Jaie 
Published: March 2007

The major obstacle for oral delivery of administered therapeutic proteins is malabsorption in the intestine. This malabsorption could be overcome by induction of neonatal FcRn [Fc (CH2 and CH3 domains of human IgG1 antibody) receptor]‐mediated transcytosis in the intestine using recombinant fusion of CH2 and CH3 moieties of human IgG to a therapeutic protein. To this end we developed recombinant hGH (human growth hormone) fused to the N‐terminus of Fc moieties [CH2‐CH3 or h (hinge)‐CH2‐CH3] from human IgG1. These recombinant proteins secreted by the methylotrophic yeast Pichia pastoris functionally induced secretion of insulin‐like growth factor 1 by HepG2 cells in the response to hGH moiety in the fusion proteins. In a transport study using polarized T84 cells, 3.7% of added dimeric hGH–h‐Fc was transported in the apical‐to‐basolateral direction within 1 h by FcRn‐mediated transcytosis of 1 cm2 monolayers. However, transport of monomeric hGH–Fc (only 0.43%) was much less effective, yet its transport was 2.3 times higher than that of hGH. Finally, we concluded that, upon recombinant fusion, maintenance of dimeric structure of Fc moieties is crucial for the induction of FcRn‐mediated transcytosis.