bluuebunny/crossref_metadata_2025_split huggingface dataset:
Advances in life‐history knowledge for 35 seahorse species from community science
Authors: Camins Elsa , Stanton Lily M. , Correia Miguel , Foster Sarah J. , Koldewey Heather J. , Vincent Amanada C. J. 
Published: February 2024

AbstractMarine community science presents an important route to gather valuable scientific information while also influencing local management and policy, thus contributing to marine conservation efforts. Because seahorses are cryptic but charismatic species, they are good candidates for engaging diverse people to help overcome the many gaps in biological knowledge. We have synthesized information contributed to the community science project iSeahorse from October 2013 to April 2022 for 35 of 46 known seahorse species. We then compared the obtained results with information in existing IUCN Red List assessments, executed from 2014 to 2017, to explore the potential of iSeahorse in expanding seahorse knowledge. Our results show updated geographic ranges for 7 seahorse species, new habitats described for 24 species, observations outside the previously recorded depth range for 14 species, and new information on sex ratio for 15 species and on pregnancy seasonality for 11 species. As one example of the power of iSeahorse, contributed observations on Coleman's pygmy seahorse (Hippocampus colemani) indicated that its geographic range is thousands of square kilometers larger, its habitat more diverse, and its depth range shallower than previously known. It is clear that iSeahorse is expanding knowledge on seahorses to a level that will help improve IUCN Red List assessments. The power of community science for marine conservation in general needs to be fully explored.
Patient portal messages to support an age‐friendly health system for persons with dementia
Authors: Gleason Kelly T. , Powell Danielle , DeGennaro Athena P. , Wu Mingche M. J. , Zhang Talan , Wolff Jennifer L. 
Published: February 2024

AbstractBackgroundPatient portal secure messaging can support age‐friendly dementia care, yet little is known about care partner use of the portal and how message concerns relate to age‐friendly issues.MethodsWe conducted a two‐part observational study. We first assessed the feasibility of automating care partner identification from patient portal messages by developing and testing a natural language processing (NLP) rule‐based classification system from portal messages of 1973 unique patients 65 and older. Second, two independent reviewers manually coded a randomly selected sample of portal messages for 987 persons with dementia to identify the frequency of expressed needs from the 4M domains of an Age‐Friendly Health System (medications, mentation, mobility, and what matters).ResultsA total of 267 (13.53%) of 1973 messages sent from older adults' portal accounts were identified through manual coding as sent by a nonpatient author. The NLP model performance to identify nonpatient authors demonstrated an AUC of 0.90. Most messages sent from the accounts of persons with dementia contained content relevant to the 4Ms (60%, 601/987), with the breakdown as follows: medications—36% (357/987), mobility—10% (101/987), mentation—16% (153/987), and what matters (aligning care with specific health goals and care preferences)—21%, 207/987.ConclusionsPatient portal messaging offers an avenue to identify care partners and meet the informational needs of persons with dementia and their care partners.
Child and family characteristics in multisystemic therapy for child abuse and neglect (MST‐CAN): Are there associations with treatment outcome?
Authors: Buderer Corinna , Kirsch Tom , Pérez Tania , Swenson Cynthia Cupit , Fürstenau Ute , Rhiner Bruno , Schmid Marc 
Published: February 2024

AbstractEvidence‐based indication for targeted interventions is a central approach in the field of child welfare and psychotherapy. This study explored the characteristics of children and families referred to Multisystemic Therapy for Child Abuse and Neglect (MST‐CAN) in Switzerland and their associations with treatment outcomes. We sought to identify subgroups of children and families referred to MST‐CAN and understand their specific needs and alignment with the program. We identified five distinct subgroups of children: (a) those characterized by clinically significant “social withdrawal” and “anxiety/depression,” (b) with multiple clinically significant emotional and behavioral problems, (c) with predominantly externalizing problems, (d) with no pathological findings at all, with parents who were less stressed and had fewer mental health problems, and (e) with mainly internalizing problems and parents whose mental health problems deteriorated during treatment. Investigating the fit of children and families referred to treatment programs can enhance the understanding of their healthcare needs and enable more individualized interventions.
Deep learning‐based skin care product recommendation: A focus on cosmetic ingredient analysis and facial skin conditions
Authors: Lee Jinhee , Yoon Huisu , Kim Semin , Lee Chanhyeok , Lee Jongha , Yoo Sangwook 
Published: February 2024

AbstractBackgroundRecommendations for cosmetics are gaining popularity, but they are not being made with consideration of the analysis of cosmetic ingredients, which customers consider important when selecting cosmetics.AimsThis article aims to propose a method for estimating the efficacy of cosmetics based on their ingredients and introduces a system that recommends personalized products for consumers, combined with AI skin analysis.MethodsWe constructed a deep neural network architecture to analyze sequentially arranged cosmetic ingredients in the product and incorporated skin analysis models to get the precise skin status of users from frontal face images. Our recommendation system makes decisions based on the results optimized for the individual.ResultsOur cosmetic recommendation system has shown its effectiveness through reliable evaluation metrics, and numerous examples have demonstrated its ability to make reasonable recommendations for various skin problems.ConclusionThe result shows that deep learning methods can be used to predict the effects of products based on their cosmetic ingredients and are available for use in personalized cosmetic recommendations.
Baiting whiteness: Ziwe Fumudoh's satirical repetition
Authors: Wood Katelyn Hale 
Published: February 2024

AbstractAnalyzing the comedy of Ziwe Fumudoh, this paper examines how repeated comedic bits can challenge white audiences' disingenuous anti‐racism, satirize toxic white womanhood in the U.S., and script what is possible when white feminists demonstrate sincere attempts at cross‐racial connection. Each artifact from Ziwe's comedy—an interview with chef Alison Roman, a musical sketch titled “Lisa Called the Cops,” and an interview with activist Gloria Steinem—carve out productive modes of confrontation. Ziwe satirizes the ridiculousness of white performative allyship and toxic white womanhood, and demonstrates the push and pull between hope and hopelessness of structural progress in the U.S.
Hybridization and gene expression: Beyond differentially expressed genes
Authors: Runemark Anna , Moore Emily C. , Larson Erica L. 
Published: February 2024

AbstractGene expression has a key role in reproductive isolation, and studies of hybrid gene expression have identified mechanisms causing hybrid sterility. Here, we review the evidence for altered gene expression following hybridization and outline the mechanisms shown to contribute to altered gene expression in hybrids. Transgressive gene expression, transcending that of both parental species, is pervasive in early generation sterile hybrids, but also frequently observed in viable, fertile hybrids. We highlight studies showing that hybridization can result in transgressive gene expression, also in established hybrid lineages or species. Such extreme patterns of gene expression in stabilized hybrid taxa suggest that altered hybrid gene expression may result in hybridization‐derived evolutionary novelty. We also conclude that while patterns of misexpression in hybrids are well documented, the understanding of the mechanisms causing misexpression is lagging. We argue that jointly assessing differences in cell composition and cell‐specific changes in gene expression in hybrids, in addition to assessing changes in chromatin and methylation, will significantly advance our understanding of the basis of altered gene expression. Moreover, uncovering to what extent evolution of gene expression results in altered expression for individual genes, or entire networks of genes, will advance our understanding of how selection moulds gene expression. Finally, we argue that jointly studying the dual roles of altered hybrid gene expression, serving both as a mechanism for reproductive isolation and as a substrate for hybrid ecological adaptation, will lead to significant advances in our understanding of the evolution of gene expression.
Functional traits of fossil plants
Authors: McElwain Jennifer C. , Matthaeus William J. , Barbosa Catarina , Chondrogiannis Christos , O' Dea Katie , Jackson Bea , Knetge Antonietta B. , Kwasniewska Kamila , Nair Richard , White Joseph D. , Wilson Jonathan P. , Montañez Isabel P. , Buckley Yvonne M. , Belcher Claire M. , Nogué Sandra 
Published: February 2024

SummaryA minuscule fraction of the Earth's paleobiological diversity is preserved in the geological record as fossils. What plant remnants have withstood taphonomic filtering, fragmentation, and alteration in their journey to become part of the fossil record provide unique information on how plants functioned in paleo‐ecosystems through their traits. Plant traits are measurable morphological, anatomical, physiological, biochemical, or phenological characteristics that potentially affect their environment and fitness. Here, we review the rich literature of paleobotany, through the lens of contemporary trait‐based ecology, to evaluate which well‐established extant plant traits hold the greatest promise for application to fossils. In particular, we focus on fossil plant functional traits, those measurable properties of leaf, stem, reproductive, or whole plant fossils that offer insights into the functioning of the plant when alive. The limitations of a trait‐based approach in paleobotany are considerable. However, in our critical assessment of over 30 extant traits we present an initial, semi‐quantitative ranking of 26 paleo‐functional traits based on taphonomic and methodological criteria on the potential of those traits to impact Earth system processes, and for that impact to be quantifiable. We demonstrate how valuable inferences on paleo‐ecosystem processes (pollination biology, herbivory), past nutrient cycles, paleobiogeography, paleo‐demography (life history), and Earth system history can be derived through the application of paleo‐functional traits to fossil plants.
Inflammation‐mediated metabolic regulation in adipose tissue
Authors: Xu Shujie , Lu Feng , Gao Jianhua , Yuan Yi 
Published: February 2024

SummaryChronic inflammation of adipose tissue is a prominent characteristic of many metabolic diseases. Lipid metabolism in adipose tissue is consistently dysregulated during inflammation, which is characterized by substantial infiltration by proinflammatory cells and high cytokine concentrations. Adipose tissue inflammation is caused by a variety of endogenous factors, such as mitochondrial dysfunction, reactive oxygen species (ROS) production, endoplasmic reticulum (ER) stress, cellular senescence, ceramides biosynthesis and mediators of lipopolysaccharides (LPS) signaling. Additionally, the gut microbiota also plays a crucial role in regulating adipose tissue inflammation. Essentially, adipose tissue inflammation arises from an imbalance in adipocyte metabolism and the regulation of immune cells. Specific inflammatory signals, including nuclear factor‐κB (NF‐κB) signaling, inflammasome signaling and inflammation‐mediated autophagy, have been shown to be involved in the metabolic regulation. The pathogenesis of metabolic diseases characterized by chronic inflammation (obesity, insulin resistance, atherosclerosis and nonalcoholic fatty liver disease [NAFLD]) and recent research regarding potential therapeutic targets for these conditions are also discussed in this review.
Feasibility of spheno‐occipital synchondrosis fusion stages as an indicator for the assessment of maxillomandibular growth: A mixed longitudinal study
Authors: Geng Jing , Zhao Guangpu , Gu Yan 
Published: February 2024

AbstractObjectivesThis study aimed to assess the relative growth rates (RGRs) of the maxilla and mandible at varying fusion stages of the spheno‐occipital synchondrosis (SOS), thereby elucidating the potential of SOS stages in predicting maxillomandibular growth.Materials and MethodsA total of 320 subjects (171 boys and 149 girls), aged 6 to 18 years, were retrospectively included. Each subject had a minimum of two longitudinal cone‐beam computed tomography (CBCT) images, with no more than one interval of SOS fusion stage change between the two scans. Subjects were categorized based on their SOS fusion stages and genders. The RGRs of the maxilla and mandible at various SOS fusion stages were measured and compared using longitudinal CBCT images.ResultsSignificant statistical differences were observed in maxillomandibular RGRs across various SOS fusion stages. In girls, the sagittal growth of the maxilla remained stable and active until SOS 3, subsequently exhibited deceleration in SOS 4–5 (compared to SOS 3–4, P < .05) and continued to decrease in SOS 5–6. Whereas in boys, the sagittal growth of the maxilla remained stable until SOS 4, and a deceleration trend emerged starting from SOS 5 to 6 (P < .01 compared to SOS 4–5). Mandibular growth patterns in both genders exhibited a progression of increasing‐accelerating‐decelerating rates from SOS 2 to 6. The highest RGRs for total mandibular length were observed in SOS 3–4 and SOS 4–5.ConclusionSpheno‐occipital synchondrosis fusion stages can serve as a valid indicator of maxillomandibular growth maturation.
The transcriptional landscape of Populus pattern/effector‐triggered immunity and how PagWRKY18 involved in it
Authors: Chen Sisi , Tan Shuxian , Jin Zhelun , Wu Jiadong , Zhao Yiyang , Xu Weijie , Liu Sijia , Li Yue , Huang Huahong , Bao Fei , Xie Jianbo 
Published: February 2024

AbstractPlants trigger a robust immune response by activating massive transcriptome reprogramming through crosstalk between PTI and ETI. However, how PTI and ETI contribute to the quantitative or/and qualitative output of immunity and how they work together when both are being activated were unclear. In this study, we performed a comprehensive overview of pathogen‐triggered transcriptomic reprogramming by analyzing temporal changes in the transcriptome up to 144 h after Colletotrichum gloeosporioides inoculated in Populus. Moreover, we constructed a hierarchical gene regulatory network of PagWRKY18 and its potential target genes to explore the underlying regulatory mechanisms of PagWRKY18 that are not yet clear. Interestingly, we confirmed that PagWRKY18 protein can directly bind the W‐box elements in the promoter of a transmembrane leucine‐rich repeat receptor‐like kinase, PagSOBIR1 gene, to trigger PTI. At the same time, PagWRKY18 functions in disease tolerance by modulation of ROS homeostasis and induction of cell death via directly targeting PagGSTU7 and PagPR4 respectively. Furthermore, PagPR4 can interact with PagWRKY18 to inhibit the expression of PagPR4 genes, forming a negative feedback loop. Taken together, these results suggest that PagWRKY18 may be involved in regulating crosstalk between PTI and ETI to activate a robust immune response and maintain intracellular homeostasis.
Drought: A context‐dependent damper and aggravator of plant diseases
Authors: Choudhary Aanchal , Senthil‐Kumar Muthappa 
Published: February 2024

AbstractDrought dynamically influences the interactions between plants and pathogens, thereby affecting disease outbreaks. Understanding the intricate mechanistic aspects of the multiscale interactions among plants, pathogens, and the environment—known as the disease triangle—is paramount for enhancing the climate resilience of crop plants. In this review, we systematically compile and comprehensively analyse current knowledge on the influence of drought on the severity of plant diseases. We emphasise that studying these stresses in isolation is not sufficient to predict how plants respond to combined stress from both drought and pathogens. The impact of drought and pathogens on plants is complex and multifaceted, encompassing the activation of antagonistic signalling cascades in response to stress factors. The nature, intensity, and temporality of drought and pathogen stress occurrence significantly influence the outcome of diseases. We delineate the drought‐sensitive nodes of plant immunity and highlight the emerging points of crosstalk between drought and defence signalling under combined stress. The limited mechanistic understanding of these interactions is acknowledged as a key research gap in this area. The information synthesised herein will be crucial for crafting strategies for the accurate prediction and mitigation of future crop disease risks, particularly in the context of a changing climate.
Periodontitis and rheumatoid arthritis—Global efforts to untangle two complex diseases
Authors: Lopez‐Oliva Isabel , Malcolm Jennifer , Culshaw Shauna 
Published: February 2024

AbstractUnderstanding the impact of oral health on rheumatoid arthritis (RA) will inform how best to manage patients with both periodontitis and RA. This review seeks to provide an update on interventional and mechanistic investigations, including a brief summary of European Research programs investigating the link between periodontitis and RA. Recent clinical studies are described that evaluate how the treatment of one disease impacts on the other, as are studies in both humans and animal models that have sought to identify the potential mechanisms linking the two diseases.
Temporal dynamics of autonomic nervous system responses under cognitive‐emotional workload in obsessive‐compulsive disorder
Authors: Portnova Galina , Khayrullina Guzal , Martynova Olga 
Published: February 2024

AbstractDysregulation of the autonomic nervous system (ANS) is commonly observed in various mental disorders, particularly when individuals engage in prolonged cognitive‐emotional tasks that require ANS adjustment to workload. Although the understanding of the temporal dynamics of sympathetic and parasympathetic tones in obsessive‐compulsive disorder (OCD) is limited, analyzing ANS reactions to cognitive‐emotional workload could provide valuable insights into one of the underlying causes of OCD. This study investigated the temporal dynamics of heart rate (HR) and pupil area (PA) while participants with OCD and healthy volunteers solved antisaccade tasks, with affective pictures serving as central fixation stimuli. The data of 31 individuals with OCD and 30 healthy volunteers were included in the study, comprising three separate blocks, each lasting approximately 8 min. The results revealed an increase in sympathetic tone in the OCD group, with the most noticeable rise occurring during the middle part of each block, particularly during the presentation of negative stimuli. Healthy volunteers demonstrated adaptive temporal dynamics of HR and PA from the first block to the last block of tasks, whereas individuals with OCD exhibited fewer changes over time, suggesting a reduced adaptation of the ANS sympathetic tone to cognitive‐emotional workload in OCD.
Suicide Crisis Syndrome: A systematic review
Authors: Melzer Laura , Forkmann Thomas , Teismann Tobias 
Published: February 2024

AbstractBackgroundThe objective of this systematic review is to describe the scientific evidence for the Suicide Crisis Syndrome (SCS), a presuicidal cognitive and affective state consisting of five symptomatic dimensions: entrapment, affective disturbance, loss of cognitive control, hyperarousal, and social withdrawal. The aim of this article is to summarize the emerging literature on the SCS and to assess the extent to which a uniform syndrome can be assumed.MethodsA systematic literature search was conducted in three different databases (PubMed, PsycInfo, and Google Scholar) using the search terms “Suicide Crisis Inventory,” “Suicide Crisis Syndrome,” “Narrative Crisis Model of Suicide,” and “Suicide Trigger State.”ResultsIn total, 37 articles from 2010 to 2022 were identified by search criteria. Twenty‐one articles published between 2017 and 2022 were included in the systematic review. All but three studies were conducted in the United States and examined clinical samples of adult high‐risk psychiatric in‐ and outpatients. Sample sizes ranged from N = 170 to 4846. The findings confirm the unidimensional structure of the proposed disorder and support the predictive validity for short‐term suicidal behavior above and beyond suicidal ideation.ConclusionDespite the promising predictive validity of the SCS, a precise prediction of future suicidal behavior remains difficult.
The MpNAC72/MpERF105‐MpMYB10b module regulates anthocyanin biosynthesis in Malus ‘Profusion’ leaves infected with Gymnosporangium yamadae
Authors: Wang Yu , An Hong , Yang Yue , Yi Cheng , Duan Ying , Wang Qian , Guo Yannan , Yao Lina , Chen Mingkun , Meng Jiaxin , Wei Jun , Hu Chenyang , Li Houhua 
Published: February 2024

SUMMARYApple rust is a serious fungal disease affecting Malus plants worldwide. Infection with the rust pathogen Gymnosporangium yamadae induces the accumulation of anthocyanins in Malus to resist rust disease. However, the mechanism of anthocyanin biosynthesis regulation in Malus against apple rust is still unclear. Here, we show that MpERF105 and MpNAC72 are key regulators of anthocyanin biosynthesis via the ethylene‐dependent pathway in M. ‘Profusion’ leaves under rust disease stress. Exogenous ethephon treatment promoted high expression of MpERF105 and MpNAC72 and anthocyanin accumulation in G. yamadae‐infected M. ‘Profusion’ leaves. Overexpression of MpERF105 increased the total anthocyanin content of Malus plant material and acted by positively regulating its target gene, MpMYB10b. MpNAC72 physically interacted with MpERF105 in vitro and in planta, and the two form a protein complex. Coexpression of the two leads to higher transcript levels of MpMYB10b and higher anthocyanin accumulation. In addition, overexpression of MpERF105 or MpNAC72 enhanced the resistance of M. ‘Profusion’ leaves to apple rust. In conclusion, our results elucidate the mechanism by which MpERF105 and MpNAC72 are induced by ethylene in G. yamadae‐infected M. ‘Profusion’ leaves and promote anthocyanin accumulation by mediating the positive regulation of MpMYB10b expression.
Remittances and inequality: A meta‐analytic investigation
Authors: Anwar Amar , Mang Colin F. , Plaza Sonia 
Published: February 2024

AbstractThis article provides a comprehensive meta‐analysis that addresses an important gap in the literature by examining the relationship between remittances and inequality in recipient countries. While numerous empirical studies have explored this relationship, there has been no prior attempt to systematically and rigorously synthesise the evidence. This study employs advanced meta‐analysis techniques, such as Bayesian model averaging, to analyse 578 estimates reported in 45 studies. The overall finding is that the effect of remittances on inequality is negative but economically small. However, significant regional variations exist, with remittances contributing to increased inequality in South Asia, while having a substantial inequality‐reducing effect in East Asia, Eastern Europe and Latin America. In the Middle East and North Africa and Sub‐Saharan Africa, only marginal economic impact is found. We recommend that future studies should control for educational attainment, income level and institutional quality to improve the accuracy of their estimates.