bluuebunny/crossref_metadata_2025_split huggingface dataset:
Delaying age at first sexual intercourse provides protection against oral cavity cancer: a mendelian randomization study
Authors: Sun Ting , He Xin , Chen Xing , Huaqing Yang , Zhang Haimei , Zhao Min , Du Li , Zhao Bin , Hou Junping , Li Xudong , Liu Yu 
Published: April 2024

AimTo investigate whether age at first sexual intercourse could lead to any changes in the risk of oral cavity cancer.MethodsA two-sample mendelian randomization was conducted using genetic variants associated with age at first sexual intercourse in UK biobank as instrumental variables. Summary data of Northern American from a previous genome-wide association study aimed at oral cavity cancer was served as outcome. Three analytical methods: inverse variance-weighted, mendelian randomization Egger, and weighted median were used to perform the analysis, among which inverse variance-weighted was set as the primary method. Robustness of the results was assessed through Cochran Q test, mendelian randomization Egger intercept tests, MR PRESSO, leave one out analysis and funnel plot.ResultsThe primary analysis provided substantial evidence of a positive causal relationship age at first sexual intercourse and the risk of oral cavity cancer (p = 0.0002), while a delayed age at first sexual intercourse would lead to a decreased risk of suffering oral cavity cancer (β = -1.013). The secondary outcomes confirmed the results (all β &lt; 0) and all assessments supported the robustness, too (all p &gt; 0.05).ConclusionThe study demonstrates that a delayed sexual debut would provide protection against OCC, thus education on delaying sexual intercourse should be recommended.
The prognostic value of prognostic nutritional index in postoperative onset of PAH in children with isolated VSD: a prospective cohort study based on propensity score matching analysis
Authors: Zhang Zeying , Su Jing , Li Chenyang , Cao Shirui , Sun Chao , Lin Qiuzhen , Luo Haiyan , Xiao Zhenghui , Xiao Yunbin , Liu Qiming 
Published: April 2024

BackgroundThe mechanism of pulmonary arterial hypertension (PAH) after surgery/intervention for isolated venticlular septal defect (VSD) in children is unknown. Reliable prognostic indicators for predicting postoperative PAH are urgently needed. Prognostic nutration index (PNI) is widely used to predict postoperative complications and survival in adults, but it is unclear whether it can be used as an indicator of prognosis in children.MethodsA total of 251 children underwent VSD repair surgery or interventional closure in Hunan Children's Hospital from 2020 to 2023 were collected. A 1:1 propensity score matching (PSM) analysis was performed using the nearest neighbor method with a caliper size of 0.2 Logistics regression analysis is used to examine factors associated with the development of PAH.ResultsThe cut-off value for PNI was determined as 58.0. After 1:1 PSM analysis, 49 patients in the low PNI group were matched with high PNI group. Children in the low PNI group had higher risk of postoperative PAH (P = 0.002) than those in the high PNI group. Multivariate logistics regression analysis showed that PNI (RR: 0.903, 95% CI: 0.816–0.999, P = 0.049) and tricuspid regurgitation velocity (RR: 4.743, 95% CI: 1.131–19.897, P = 0.033) were independent prognostic factors for the development of PAH.ConclusionPNI can be used as a prognostic indicator for PAH development after surgery/intervention in children with isolated VSD.
Case report and literature review: Asymptomatic littoral cell angioma in a 3-year-old girl
Authors: Mou Yanling , Yang Liucheng , Wang Jianjun , Chen Qinming , Zhang Mengzhen , Zhang Xi , Tan Rongying , Adam Mahamat Djibril , Wu Kai 
Published: April 2024

BackgroundLittoral cell angioma (LCA) is an extremely uncommon benign vascular tumor of the spleen. Cases of LCA in infants are rarely reported, and due to the rarity of the tumor and non-specific symptoms, the diagnosis of LCA is often overlooked in clinical practice.Case reportWe present a 3-year-old girl with pulmonary inflammation who was admitted to the hospital due to the discovery of a space-occupying lesion in the spleen. Pathology after splenectomy confirmed LCA, and there was no recurrence observed at the 5-month follow-up examination.ConclusionLCA should be considered when a child shows asymptomatic splenomegaly, with antigen expression indicating dual positivity of endothelial and histiocytic markers. Laparoscopic splenectomy remains the primary method of treating LCA.
How do the cognitive processes matter in the event-based preschoolers’ prospective memory?
Authors: Szpakiewicz Elżbieta , Stępień-Nycz Małgorzata 
Published: April 2024

BackgroundProspective memory (PM) is the ability to remember to perform an intended action at a specific future moment. The current study examined the impact of age, task focality, and cue salience on PM in children aged 2 to 6 years, based on the multiprocess theory of PM and the executive framework of PM development. Additionally, the study explored the relationship between various cognitive abilities and their association with PM performance.MethodsA total of 224 preschool-aged children, aged 2–6, engaged in event-based PM tasks with varying cognitive demands. The tasks were either focal or nonfocal, with salient or nonsalient cues. Additionally, individual differences in cognitive abilities were measured.ResultsThe results support previous indications that even very young children can successfully complete event-based PM tasks. The accuracy of PM display improved with age, especially between the ages of 3 and 4. Better performance was observed in focal PM tasks compared to nonfocal PM tasks. Additionally, preschoolers’ PM performance correlated with various cognitive abilities, including fluid intelligence, retrospective memory, inhibitory control, working memory, and language ability. These correlations varied depending on the child’s age and the task’s nature. For both focal and nonfocal PM tasks, cognitive abilities partially mediated the relationship between age and PM performance.ConclusionIn summary, this study comprehensively explores the specific roles played by age and fundamental cognitive abilities in event-based PM performance among preschool-aged children.
Association between residential environment and emotional wellbeing among older adults in China: the mediating effect of health lifestyle
Authors: Huijie Zhu , Haojun Jiang , Zhiping Zhu , Zhaoyu Yao 
Published: April 2024

IntroductionThe association between the residential environment and emotional wellbeing (EWB) in older adults has received extensive attention from gerontologists, especially during the COVID-19 pandemic; however, the mediating mechanism of how residential environment affects emotional wellbeing has not been fully explored. This study examined the effects of the residential environment on EWB and the mediating role of health lifestyle.MethodsThis study analyzed the survey data of 493 rural and 515 urban older adults from 2021 Chinese General Social Survey. General linear regression and structural equation models were used to examine the effects of residential environment and health lifestyle.ResultsUrban participants exhibited clear advantages in EWB, residential environment, and physical activity. Residential environment significantly affected the EWB of older adults, and health lifestyle played a mediating role in this relationship. The residential environment and health lifestyle did not significantly affect EWB in rural participants.DiscussionThis study revealed differences in the effects of health lifestyles and residential environments on EWB among older adults in rural and urban settings in China. This study provided empirical evidence of mental health disparities between older rural and urban Chinese residents.
Understanding the experiences of PHC nurses in caring for older patients in the post-fifth wave of the COVID-19 pandemic: an exploratory qualitative study
Authors: Ślusarska Barbara , Nowicki Grzegorz Józef , Chrzan-Rodak Agnieszka , Marcinowicz Ludmiła 
Published: April 2024

ObjectiveTo ensure the best possible care, the perspective of PHC nurse work experience during the COVID-19 pandemic should be considered when developing nursing care protocols for older patients who receive PHC services.MethodThis exploratory qualitative study was conducted with 18 nurses working continuously in PHC between the first and fifth waves of the pandemic. Semi-structured thematic interviews were undertaken. Qualitative thematic content analysis was conducted to identify and group the themes that emerged from the discourse. Interviews were transcribed and analyzed using thematic analysis.ResultsThe first topic describes the nurses’ experiences of physical and mental suffering in caring for older patients in response to the pandemic. The second topic covers the experience of reorganizing PHC work. The third topic focuses on the difficulties of caring for older patients. The final topic includes issues of support needs for nurses in PHC work.ConclusionThe experience and understanding of PHC nurses in caring for older people during the COVID pandemic should lead to significant changes in the system of nursing care for geriatric patients and in the cooperative role within geriatric care specialist teams. Drawing on the experience of COVID-19, it is necessary to work on the weak points of PHC exposed by the pandemic in order to improve the quality of care and life for geriatric patients.
Effective analysis of job satisfaction among medical staff in Chinese public hospitals: a random forest model
Authors: Li Chengcheng , Meng Xuehui 
Published: April 2024

ObjectiveThis study explored the factors and influence degree of job satisfaction among medical staff in Chinese public hospitals by constructing the optimal discriminant model.MethodsThe participant sample is based on the service volume of 12,405 officially appointed medical staff from different departments of 16 public hospitals for three consecutive years from 2017 to 2019. All medical staff (doctors, nurses, administrative personnel) invited to participate in the survey for the current year will no longer repeat their participation. The importance of all associated factors and the optimal evaluation model has been calculated.ResultsThe overall job satisfaction of medical staff is 25.62%. The most important factors affecting medical staff satisfaction are: Value staff opinions (Q10), Get recognition for your work (Q11), Democracy (Q9), and Performance Evaluation Satisfaction (Q5). The random forest model is the best evaluation model for medical staff satisfaction, and its prediction accuracy is higher than other similar models.ConclusionThe improvement of medical staff job satisfaction is significantly related to the improvement of democracy, recognition of work, and increased employee performance. It has shown that improving these five key variables can maximize the job satisfaction and motivation of medical staff. The random forest model can maximize the accuracy and effectiveness of similar research.
Temporal change in multimorbidity prevalence, clustering patterns, and the association with mortality: findings from the China Kadoorie Biobank study in Jiangsu Province
Authors: Yu Hao , Tao Ran , Zhou Jinyi , Su Jian , Lu Yan , Hua Yujie , Jin Jianrong , Pei Pei , Yu Canqing , Sun Dianjianyi , Chen Zhengming , Li Liming , Lv Jun 
Published: April 2024

ObjectivesThe characteristics of multimorbidity in the Chinese population are currently unclear. We aimed to determine the temporal change in multimorbidity prevalence, clustering patterns, and the association of multimorbidity with mortality from all causes and four major chronic diseases.MethodsThis study analyzed data from the China Kadoorie Biobank study performed in Wuzhong District, Jiangsu Province. A total of 53,269 participants aged 30–79 years were recruited between 2004 and 2008. New diagnoses of 15 chronic diseases and death events were collected during the mean follow-up of 10.9 years. Yule's Q cluster analysis method was used to determine the clustering patterns of multimorbidity. A Cox proportional hazards model was used to estimate the associations of multimorbidity with mortalities.ResultsThe overall multimorbidity prevalence rate was 21.1% at baseline and 27.7% at the end of follow-up. Multimorbidity increased more rapidly during the follow-up in individuals who had a higher risk at baseline. Three main multimorbidity patterns were identified: (i) cardiometabolic multimorbidity (diabetes, coronary heart disease, stroke, and hypertension), (ii) respiratory multimorbidity (tuberculosis, asthma, and chronic obstructive pulmonary disease), and (iii) mental, kidney and arthritis multimorbidity (neurasthenia, psychiatric disorders, chronic kidney disease, and rheumatoid arthritis). There were 3,433 deaths during the follow-up. The mortality risk increased by 24% with each additional disease [hazard ratio (HR) = 1.24, 95% confidence interval (CI) = 1.20–1.29]. Compared with those without multimorbidity at baseline, both cardiometabolic multimorbidity and respiratory multimorbidity were associated with increased mortality from all causes and four major chronic diseases. Cardiometabolic multimorbidity was additionally associated with mortality from cardiovascular diseases and diabetes, with HRs of 2.64 (95% CI = 2.19–3.19) and 28.19 (95% CI = 14.85–53.51), respectively. Respiratory multimorbidity was associated with respiratory disease mortality, with an HR of 9.76 (95% CI = 6.22–15.31).ConclusionThe prevalence of multimorbidity has increased substantially over the past decade. This study has revealed that cardiometabolic multimorbidity and respiratory multimorbidity have significantly increased mortality rates. These findings indicate the need to consider high-risk populations and to provide local evidence for intervention strategies and health management in economically developed regions.
Binderless particleboards obtained 100% from winery by-products for the packaging industry
Authors: Fernandes Raquel A. , Lopes Sandro , Ferreira Nuno , Santos Jorge , Martins Jorge M. , Carvalho Luisa H. 
Published: April 2024

The valorization of bioeconomy by-products holds immense significance in achieving sustainability goals and fostering resource efficiency, not only to reduce the amount of waste generated but also to significantly decrease the carbon footprint associated with several industrial fields, by promoting circular economy. The wine industry is not only one of the major contributors for world’s economy but also a great producer of by-products, with no valorization process associated. Grape stalks are a great source of chemical molecules, as polyphenols, that can be applied in the production of bio-adhesives. In the present work, grape stalk particles were used as raw material to obtain a highly rich extract with bonding properties through solid/liquid extraction. Different extraction agents were tested (water, NaOH, and Na2CO3) at varied concentrations (0.1%, 0.5%, and 1.0%, respectively). Additionally, extracts were chemically characterized, and the bonding capacity was also evaluated. Using NaOH 1.0%, an extraction efficiency of 8.9% and a total content of polyphenols of 1.4% were achieved. Moreover, all extracts presented an interesting bonding capacity (&gt;1.0 MPa) by hot-press at 120°C for 120 s. The composite panel produced using grape stalk adhesive and vine strain particles fulfills the requirements for type P1 particleboards in terms of internal bond strength, reaching 0.66 MPa. The mechanical and wettability properties of composite material allow foreseeing a promising application in the food packaging industry.
Effect of Transformational Leadership and Work Stress on Organizational Citizenship Behavior with Organizational Commitment as an Intervening Variable
Authors: Arrozi Muhammad Fachruddin , Tirtayasa Charli Otman , Nofiarni Nofiarni 
Published: April 2024

Background. Organizational citizenship behavior (OCB) is defined as behavior that goes beyond formally defined roles and is not stated in the job description. Objective: The study aimed to examine the effect of Organizational Citizenship Behavior (OCB) that are influenced by the Transformational Leadership of the Head of the Inpatient Room, work stress, and nurse organizational commitment simultaneously. Method: This research uses a survey method with an explanatory causality approach. Data was collected by using a questionnaire and tested using Multiple Linear Regression Analysis. Result: Transformational leadership, job stress, and organizational commitment significantly affect organizational citizenship behavior simultaneously. Transformational leadership is the biggest factor. Organizational commitment can mediate the effect of Transformational Leadership and work stress on Organizational Citizenship Behavior. Transformational leadership significantly affects Organizational Commitment, Work Stress significantly affects Organizational Commitment, Organizational Commitment significantly affects Organizational Citizenship Behavior, and Transformational Leadership significantly affects Organizational Citizenship Behavior. Work stress significantly affects Organizational Citizenship Behavior. Implication: This study helps hospital management to promote a more effective work culture through Transformational Leadership training, Organizational Citizenship Behavior of Heads of Inpatient rooms, and a new method of selecting new nurses recruitment by HRD and long-term prosocial improvement for senior employees
Factors Associated with the Incidence of Diabetic Ulcers in Clients with Diabetes Mellitus at Labuang Baji Hospital Makassar
Authors: Nusdin Nusdin , Awaluddin Achmad Indra 
Published: April 2024

Background: Diabetes Mellitus is classified into a group of metabolic diseases with specific characteristics of increased blood sugar levels or hyperglycemia. Clients with Diabetes Mellitus have the potential for 15-25% to experience diabetic foot ulcers caused by the factors of cholesterol, use of footwear, and self-management of diabetes mellitus. Objectives: This study aims to determine factors associated with the incidence of diabetic ulcers in clients with diabetes mellitus at Labuang Baji Hospital Makassar. Methods: The type of research used was quantitative with a cross-sectional design. The number of samples used was 50 respondents by using accidental sampling. The research instrument used a questionnaires and Standard Operating Procedures for cholesterol examination. Result: The study results using the Spearman Correlation Testshowed a relationship between cholesterol and the incidence of diabetic ulcers in clients with Diabetes Mellitus with the p-value = 0.001 (p <0.05). There is a relationship between footwear usage and the incidence of diabetic ulcers in clients with diabetes mellitus with the p-value = 0.001 (p < 0.05) and there is a relationship between Self Management Diabetes Mellitus (SMDM) with the incidence of diabetic ulcers in clients with diabetes mellitus with p-value = 0.001 (p<0.05). Conclusion: Cholesterol, footwear usage, and Diabetes Mellitus Self Management (SMDM) are the factors of Diabetic ulcers in clients with diabetes mellitus. Recommendation: This study could be an adjunct for further systemic review and expected for further study to research about the other factor or the effect of treatment sequacity on diabetic ulcer recovery
The Influence of Workload, Knowledge, Motivation on Medical Record Quality Through Doctor Compliance
Authors: Arrandhikasari Devina , Pamungkas Rian Adi , Saptaningsih Agusdini Banun 
Published: April 2024

Background. Medical records are records and documents containing the patient's identity, examination, treatment, actions and other services that have been provided to patients. Medical records are said to be of high quality if the data and information are complete and can be read by those entitled to it from time to time as a continuous communication tool. Objective: The study aimed to analyze the effect of workload, knowledge and motivation through doctor compliance that can improve the medical record quality. Method: This study uses a quantitative approach with a causal design research using SPSS-Path Analysis. Result: There was no effect of workload on the quality of medical records through doctor's compliance, there was an influence of knowledge on the quality of medical records through doctor's compliance and there was an influence of motivation on the quality of medical records through doctor's compliance. Implication: This study proves that the amount of doctor's compliance is able to mediate the effect of knowledge and motivation which can improve the quality of medical records. Hospital management is expected to be able to motivate doctors to understand changes in the current digitalization era and to improve the level of awareness of doctors to work in an orderly administration.

Keywords: Compliance, Knowledge, Medical Record Quality, Motivation, Workload
Inkluzyjna ‘świętość’: wybrane zagadnienia eklezjologii i soteriologii płockiego nurtu w mariawityzmie
Authors: Mames Tomasz Dariusz 
Published: April 2024

Tekst dotyczy problematyki inkluzyjnego ujęcia zagadnienia ‘świętości’ w dwóch aspektach mariawickiej refleksji teologicznej: eklezjologii i soteriologii. Punktem wyjścia rozważań jest ukazanie świętości jako zagadnienia ekumenicznie ważnego, ale także i newralgicznego. Zaprezentowana jest także mariawicka optyka rozumienia pojęcia ‘świętość’ oraz propozycja modelu hagiopamięci, dotykającego pogranicza doświadczenia jednostkowego oraz wspólnotowego świętości w Kościele Starokatolickim Mariawitów. Problematyka ta skłania do refleksji wokół pytań o powszechność zbawienia, kwestię potępienia, wiecznej szczęśliwości lub kary czy reinkarnacji.
Where does the hendiadys in Phil. 1:1 come from? About the origins, misunderstandings, and argumentation of a questionable theory in English commentaries on Philippians 1:1
Authors: Olek Grzegorz 
Published: April 2024

In Philippians 1:1 two terms can be found that sound puzzling for a Pauline greeting: σύν ἐπισκόποις καὶ διακόνοις. There are English speaking exegetes who consider a hendiadys in this fragment as one possibility among many other interpretations. The following article is dedicated to the question of why a hendiadys, of all things, would be found in Phil. 1:1 and why this idea occurs almost exclusively in English commentaries – in contrast to German commentaries. Four commentaries mentioning a hendiadys are subsequently analyzed to explore and verify the rationale in favour of a hendiadys. In the analysis, the concept of hendiadys is explained in more detail followed by the suggestion that hendiadys in Phil. 1:1 is primarily based on unclear definitions and misunderstandings.