bluuebunny/crossref_metadata_2025_split huggingface dataset:
Clinical and Epidemiological Characteristics of a Contingent of Elderly Patients Treated in the Somatopsychiatric Department of a Multi-Field Hospital
Authors: Ryakhovskiy V. V. , Mazus V. A. 
Published: March 2024

Background: comorbidity of somatic and mental pathology is the most common reason that complicates the provision of medical care to the elderly even under the conditions of a specialized somatopsychiatric department (SPD) of a multi-field hospital, which dictates the need for further study of the clinical and epidemiological features of these patients population.The aim of the study was to investigate the clinical and epidemiological characteristics of a contingent of elderly patients treated over a year in SPD of a multi-field hospital in comparison with similar data from a psychiatric hospital. The objectives of the study were to analyze the demographic structure of this contingent, the distribution of various types (categories) of somatic and mental pathology, routes of admission, time and outcomes of treatment in SPD of a multidisciplinary hospital.Materials and methods: the research material was the medical documentation of a sample of patients treated during 2019 in the SPD of the City Clinical Hospital № 1 named after. N.I. Pirogov of the Moscow Department of Health Protection (the total number of patients treated was 3379 people, of which 1456 were aged 65 and older). To conduct a comparative analysis, we used data from an epidemiological study in a psychiatric hospital (City Psychiatric Hospital № 13 of the Moscow Department of Health Protection), conducted in the same 2019 year.Results: it was established that in the SPD of a multi-field hospital, care is provided to a heterogeneous (demographic and clinical-diagnostic) group of patients, predominantly of late age (65 years and older). The most common diagnosis is dementia of various origins, complicated by severe somatic pathology (acute or associated with decompensation of a chronic somatic disease).Conclusion: elderly and senile patients make up more than half of the contingent of patients treated in the SPD of a multidisciplinary hospital. Significant differences were revealed in the SPD diagnostic distribution of young-middle-aged and elderly patients. Special features of the gender and age distribution of patients in the indicated age groups were established. Data were obtained on a higher mortality rate for those aged 65 years and older. The presence of problems in providing care to patients of older age groups in SPD determines the need for its improvement. For this purpose, it is advisable to consider the issue of creating a model of SPD of geriatric profile in a multi-field hospital to provide emergency psychiatric and somatic care to elderly patients.
Psychosis Due to Osmotic (Pontine) Myelinolysis in Non-Hodgkin’s Lymphoma: Case Report
Authors: Pichikov A. A. , Tikhomirov D. I. , Sorokin M. Yu. , Lukina L. V. , Grebenshchikova R. V. 
Published: March 2024

Introduction: central pontine myelinolysis (CPM) is rare neurological condition. The severe symptoms of neurologic and psychiatric disorders accompanying this condition are not sufficiently disclosed in the literature. Most often CPM develops on infusion therapy and forced correction of hyponatremia. The complexity of diagnosis and the lack of certain algorithms for the management of this category of patients cause a high frequency of disability, persistent neurological and psychiatric symptoms, and lethal outcomes.The aim was to present and analyze clinical picture of psychosis in CPM on the example of non-Hodgkin’s lymphoma case report. Patient and method: clinical analysis of disorders in 14-years old patient with diagnosis of non-Hodgkin’s lymphoma.Results: clinical polymorphism of psychotic features, catatonic disorders, neurological symptoms at the end stage and development of psychosis associated with CPM during cytotoxic treatment. A year and a half follow-up of the first generation antipsychotics administration is presented.Conclusion: CPM may occur on cytotoxic infusion therapy in patients with non-Hodgkin’s lymphoma and be accompanied by severe psychotic disorders. Thus, practitioners should be aware of the risks of this condition, its diagnostic and therapeutic options when working with these patients.
Diagnostics and Assessment of the Severity of Alzheimer’s Disease: Machine Learning Algorithms Based on Markers of Inflammation
Authors: Androsova L. V. , Simonov A. N. , Senko O. V. , Mikhaylova N. M. , Kuznetsova A. V. , Klyushnik T. P. 
Published: March 2024

Background: as the most common form of dementia, Alzheimer’s disease (AD) is characterized by cognitive deterioration and usually begins with loss of memory of recent events. It is important to search for biological, sensitive and affordable methods that could be used for early diagnostics of AD and determine the severity of the disease.Objective: to develop machine learning algorithms based on such inflammatory markers as the enzymatic activity of leukocyte elastase (LE) and the functional activity of the α1-proteinase inhibitor (α1-PI) for diagnosing and assessing the severity of AD.Patients and methods: the study included128 people aged 55 to 94 years (73.7 ± 7.9 years), of which 91 patients were diagnosed with Alzheimer’s disease and 37 apparently healthy people (control). The indicators of LE and α1-PI in blood plasma were used as classifying features for building models. The following algorithms were used to build a machine learning model: Optimal Valid Partition (OVP), logistic regression (LR), support vector machine (SVM), random forest (RF), gradient boosting (GB) and statistically weighted syndromes (WSWS). The predictive performance of the constructed classiers was evaluated by the overall accuracy (accuracy), sensitivity (sensitivity), specificity (specificity), F-measure and ROC-analysis.Results: the developed machine learning algorithms made it possible to reliably divide the general group of subjects (patients + conditionally healthy), as well as patients with different AD severity, into 4 quadrants of a two-dimensional diagram in the LE and α1-PI coordinates and showed close and fairly high predictive efficiency.Conclusion: the developed machine learning algorithms have proven close and sufficiently high prognostic efficacy for assessing the severity of AD based on inflammatory markers (enzymatic activity of LE and functional activity of α1-PI) and, probably, can be useful for early diagnostics of the disease and timely administration of therapy.
MicroRNAs as Potential Biomarkers of Mental Disorders: Diagnostic and Prognostic Implications
Authors: Tereshchenko S. Yu. 
Published: March 2024

Background: microRNAs are small non-coding RNAs that play a crucial role in post-transcriptional regulation of gene expression. Recent studies indicate the involvement of microRNAs in the pathogenesis of various psychiatric disorders, which allows to consider them as diagnostic biomarkers and therapeutic targets.The aim of this literature review is to analyse curren research on the involvement of microRNAs in the formation of psychiatric disorders, focusing on their potential as diagnostic and prognostic biomarkers. Materials and methods: to find relevant publications, we searched eLibrary and PubMed databases using the following keywords and terms: microRNAs, mental disorders, psychological status, biomarkers, diagnosis, prognosis.Conclusion: numerous studies suggest that microRNAs are involved in the regulation of critical molecular pathways associated with psychiatric disorders, including neurotransmission, neurodevelopment, and synaptic plasticity. Dysregulation of certain microRNAs has been observed in various psychiatric disorders such as major depressive disorder, schizophrenia, bipolar disorder, anxiety disorders, autism spectrum disorders, attention-deficit/hyperactivity disorder and addictive disorders. It is highlighted that the investigated microRNAs have a high potential to be used as diagnostic biomarkers, opening up possibilities for early detection and personalised treatment strategies. The identification of specific microRNAs associated with different psychiatric disorders offers new opportunities to develop innovative diagnostic approaches and targeted therapeutic interventions. However, a number of challenges remain, including differences in microRNA expression levels and profiles due to the heterogeneity of psychiatric disorders, the need for standardisation of microRNA analysis protocols and their further validation in large-scale studies on different patient populations. Collaborative efforts between basic genetics researchers and clinicians are needed to harness the full potential of microRNA analysis for the diagnosis and treatment of psychiatric disorders.
Pemberdayaan Masyarakat Melalui Komoditas Unggulan Pesisir di Teluk Arguni, Kabupaten Kaimana
Authors: Sonbait Lukas Y , Numberi Alosius , Fenitruma Abidin , Wanma Alfredo Ottow , Rayaar Matheos , Cahyaputra Arya Sadewa , Pattiselanno Freddy 
Published: March 2024

Komoditas unggulan di Teluk Arguni Kaimana memiliki nilai tinggi dan dikelola secara langsung oleh masyarakat setempat. Survey potensi komoditas unggulan pesisir masyarakat dan rencana pengembangannya sesuai dengan program pemerintah daerah kabupaten Kaimana.Potensi pesisir di Arguni sangat beragam antara lain ikan ganadi, kepiting, ikan Sembilan, udang, ikan kakap putih dan merah. Selain ikan, udang, kepiting, dan kerang-kerangan yang dimanfaatkan dagingnya dalam bentuk segar ataupun ikan asin, dari komoditas perikanan juga dipasarkan gelembung atau pelampung dari ikan gulama yang sudah dikeringkan dalam berbagai ukuran. Sektor perikanan laut ini berkontribusi signifikan terhadap tingkat pendapatan masyarakat nelayan di Teluk Arguni. Pengetahuan tentang komoditas yang dimanfaatkan cukup baik, karena aktivitas melaut ini merupakan aktivitas turun temurun yang dipraktekan oleh masayarakat setempat. Potensi komoditas pesisir mampu untuk memenuhi kebutuhan konsumsi rumah tangga sehari-hari. Pengembangan ke dalam skala yang lebih luas memerlukan aktivitas produksi secara intens sehingga mampu meningkatkan produksi secara optimal untuk mencapai pendapatan tunai yang lebih besar.
Reaktivasi Ecowisata Berbasis Masyarakat Pinus Motilango
Authors: Ariawan Ariawan , Jupri Jupri , Surusa Frengki Eka Putra 
Published: March 2024

Pandemi covid 19 membuat sektor pariwisata mengalami turbulensi. Destinasi wisata diharapkan mampu meningkatkan perekonomian masyarakat. Namun sejak pandemi covid 19 mewabah, Ekowisata Pinus Motilango mengalami penurunan jumlah pengunjung dan bahkan sempat ditutup untuk menghindari penularan diantara pengunjung. Upaya mengatasi permasalahan dapat di lakukan reaktivasi dengan konsep pengembangan ekowisata berbasis masyarakat. Metode yang digunakan Focus Group discusion (FGD), penyuluhan, pelatihan, pendampingan serta simulasi dan praktek dilakukan dengan tiga tahapan yaitu tahap Kordinasi, tahap pelaksanaan dan tahap evaluasi. Hasil dari reaktivasi berdasarkan Program-program yang telah dilaksanakan seperti memberikan pengetahuan dan ketrampilan melalui pelatihan manajemen dan pemasaran, dan penyuluhan hukum serta pembangunan fasilitas memberikan dampak pada peningkatan perekonomian masyarakat dikawasan Ekowisata Pinus Motilango dengan menjadi pengelola serta menciptakan lapangan usaha baru seperti berdagang sehingga pendapatan dan peningkatan taraf hidup mereka mengalami perubahan.
Bentuk Kesalahan Berbahasa pada Pidato Mahasiswa yang Berperan sebagai Kepala Desa Terpilih
Authors: Sartika Dewi , Sabardila Atiqah 
Published: March 2024

Tujuan dari penelitian ini adalah untuk mengkarakterisasi kesalahan linguistik yang dilakukan oleh mahasiswa MPBI-UMS saat memerankan kepala desa terpilih. Penelitian ini menggunakan strategi deskriptif kualitatif. Kata, frase, klausa, dan kalimat dari pidato penerimaan yang diberikan oleh mahasiswa MPBI-UMS setelah terpilih menjadi kepala desa dimasukkan dalam kumpulan data untuk dianalisis. Wacana lisan siswa berfungsi sebagai sumber data, sedangkan metodologi mendengarkan dan mencatat berfungsi sebagai teknik pengumpulan data. Analisis padanan referensial, analisis padanan fonetik artikulatoris, analisis perluasan dalam metode agih, dan analisis pembacaan tanda digunakan untuk menganalisis data. Berikut adalah temuan dari investigasi ini yaitu terdapat 20 data bentuk kesalahan berbahasa yang meliputi: (1) Kesalahan pada bidang fonologi: Ditemukan 5 data bentuk kesalahan berbahasa, termasuk kesalahan dalam penulisan, penghilangan fonem vokal, kesalahan dalam penulisan huruf kapital, dan kesalahan dalam penulisan cetak miring. (2) Kesalahan pada bidang morfologi: Terdapat 1 data bentuk kesalahan berbahasa, yaitu pengulangan kata atau reduplikasi. (3) Kesalahan pada bidang sintaksis: Terdapat 12 data bentuk kesalahan berbahasa, yang meliputi kesalahan dalam penulisan kalimat atau kata mubadzir, penggunaan kata tidak baku, dan kalimat tidak jelas. (4) Kesalahan ejaan: Terdapat 2 data bentuk kesalahan ejaan, yakni kesalahan dalam penggunaan tanda baca. Kesalahan berbahasa bisa terjadi dikarenakan kurangnya pemahaman penutur terhadap kaidah bahasa Indonesia yang baik dan benar. Melalui pembelajaran bahasa yang rutin, kompetensi berbahasa seseorang dapat diperbaiki menjadi lebih baik.Kata kunci: Kesalahan Berbahasa; Mahasiswa; Berpidato.
TEACHER’S METHODS IN TEACHING INTEGRATED LISTENING AND SPEAKING AT ENGLISH DEPARTMENT
Authors: Ayuningtyas Febiola Mutri , Wiyanah Sri 
Published: March 2024

Teaching integrated listening and speaking has become crucial part of the curriculum. It helps leaners to communicate effectively and become more confident in learning. Therefore, it is essential for teacher to use the appropriate method when teaching these skills. The research purposes were to describe the teacher’s’ method in teaching integrated listening and speaking at English department and find students’ perception toward it. This study used qualitative method. It employed observation, interview, and documentation as a data collecting instrument. The research subjects were one teacher and four students of fourth semester in English department at Universitas PGRI Yogyakarta. The findings showed that teacher used post-method to teach integrated listening and speaking. The method indicated more flexible and can accommodate the students’ needs. The student’s perception towards the teacher’s method was positive due to students’ feeling of growing pleasure, interesting process and suitable method to easily learn by using Post-method.
THE EFFECT STORYTELLING TO 2ND SEMESTER STUDENTS OF UNIVERSITY MUHAMMADIYAH TANGERANG
Authors: Arjulayana Arjulayana - , Nargis Nargis - 
Published: March 2024

ABSTRACT Storytelling is an activity or activity to tell a story organize and attractively. This research is aimed to discover the differences between students who given storytelling and the students who given conventional technique in improving students’ speaking skill. The research conducted to 2nd semester student from universitas Muhammadiyah Tangerang with the total sample is 56 students. The methodology of the research is quantitative approach with quasi experimental method. The researcher did 2 tests, consist of pre-test and post-test. This research was conducted of two classes, control class and experiment class. The result of the research shows that students who taught by using storytelling have higher score than the students who taught by using conventional technique. The students can explore their ideas well and more interested in learning speaking by using storytelling. As suggestion, the researcher hopes that the teachers must be able to choose appropriate technique and media in teaching English.
Students’ Motivation in Reading English Recount Texts in Junior High School
Authors: Apoko Tri Wintolo , Putri Sintya Winanda , Inayah Tarisa Marta , Maharani Sekar Fuan 
Published: March 2024

Reading is one of the important skills in learning English and motivation plays an important role in influencing reading outcomes and experiences. Students' motivation needs to be increased as it affects other skills in learning English. This study aims to determine the level of the students’ motivation in reading English Recount Text. The descriptive quantitative research was carried out in this study in order to collect information or data. The instrument used for data collection was the Reading Motivation Questionnaire (RMQ) developed by Wigfield. Thirty students at one reputable junior high school were participated on filling in 15 statements regarding motivation in reading English Recount Text. The finding indicated that students’ motivation in reading English recount texts was at a high level. The most significant reason comes from extrinsic motivation in reading Recount Text. This study is helpful for teachers to discover factors affecting students' motivation in reading Recount Text.
THE DEVELOPMENT OF LEARNING MEDIA BASED INTERACTIVE MATH COMIC FOR STUDENTS OF VIII GRADE JUNIOR HIGH SCHOOL
Authors: Niniwati Niniwati , Saputra Rahmanda , Amelia Puspa 
Published: March 2024

The ability of teachers to take advantage of technological developments in learning is highly expected so that students' attention increases in following the Learning process, one obstacle faced by students is the difficulty of understanding the material of cubes and blocks and their formulas. The purpose of this study is to develop interactive comic learning media that is expected to solve problems faced by students and teachers in learning. This Learning Media will be packaged in the form of an interactive Learning CD. This type of research is development research or Development Research. The development research model that the author uses is a computer-aided learning product development model (PBK). Validation is carried out by experts consisting of two lecturers and one teacher to see if this learning media is valid. From the results of the validity test questionnaire analysis conducted by the validator, it can be concluded that the overall validation results for interactive mathematics comic learning media obtained were 87.50 with valid criteria. While the practicality test was carried out by 26 students to see whether this learning media was practical to use or not. From the results of the analysis of student practicality questionnaire sheets, it was obtained that overall student assessment of the learning media used was 89.29% with practical criteria.
MATHEMATICAL LITERACY SKILLS BY USING REALISTIC MATHEMATICS EDUCATION-BASED WORKSHEETS
Authors: Trinanda Bunga , Sari Novita , Sukmaningthias Novika , Simarmata Ruth Helen 
Published: March 2024

This research aims to measure students' mathematical literacy skills after using e-worksheets based on the Realistic Mathematics Education (RME) Approach. This research uses a descriptive qualitative approach. Students in class VIII of SMP N 1 Talang Kelapa, each with low, medium, and high literacy skills, were the subjects of this research. The categorization of students is based on the number of mathematical literacy components resulting from student answers on the test. Data was collected through observation, tests, and interviews. The purpose of observation is to measure the implementation of learning through RME, and the test is to measure students' literacy skills. In data analysis, the elements that appear most frequently are communication, mathematization, and the use of symbolic, formal, and technical language operations. Component 1 appears when students write a statement containing information about a problem and representing the results obtained. Component 2 emerges when students create a mathematical model of the problem, and component 7 emerges when students use formal forms that conform to mathematical definitions and rules. The results of learning observations carried out using e-worksheets based on the RME approach show that learning can be said to be of good quality according to the established criteria.
Meningkatkan Prestasi Belajar Bahasa Inggris Materi Teks Deskriptif orang Melalui Model Discovery Learning pada Siswa Kelas X-A SMA N 1 Bangun Purba
Authors: Dwi Indra Gusti  
Published: March 2024

Penelitian ini bertujuan agar melalui model discovery learning dapat meningkatkan prestasi belajar Bahasa Inggris materi teks deskriptif orang pada siswa kelas X-A SMA N 1 Bangun Purba semester genap tahun pelajaran 2019/2020. Prosedur penelitian ini dilaksanakan dalam dua siklus, dimana kedua siklus itu saling berkaitan artinya siklus dua merupakan kelanjutan dari siklus satu. Setiap siklus meliputi : 1) Tahapan perencanaan, 2) Tahapan pelaksanaan tindakan, 3) Observasi/evaluasi, dan 4) Tahapan refleksi. Pelaksanaan tiap siklus terdiri dari 2 kali pertemuan . Dalam mengumpulkan data, peneliti menggunakan satu teknik pengumpulan data yakni dengan tes subyektif yang berjumlah 10 butir soal dalam bentuk uraian. Hasil penelitian ini menunjukkan bahwa pada saat pra siklus, nilai rata-rata yang diperoleh hanya 64,57 naik sebesar 3,46 menjadi 68,03 pada siklus I. Pada siklus II, nilai rata-rata kelas menjadi 78,40 menunjukkan kenaikan sebesar 13,83 dari siklus I. yang cukup positif juga terjadi pada kenaikan perolehan nilai yang memenuhi batas nilai KKM yang telah ditentukan yaitu pada pra siklus hanya 40,00 % siswa yang mampu mencapai batas KKM ( Kriteria Ketuntasan Minimal ), pada siklus I prosentase siswa yang memenuhi batas KKM naik sebesar 19,23% menjadi 56,67%. Kenaikan prosentase terus terjadi pada siklus II. Pada siklus akhir ini prosentase siswa yang memenuhi nilai KKM menjadi 90,00%, berarti naik sebesar 33,33% dari siklus I dan sebesar 50,00% dari pra siklus. Dengan demikian berarti dari data tersebut di atas bahwa dengan melalui model discovery learning pada pembelajaran siswa kelas X-A SMA N 1 Bangun Purbasemester genap tahun pelajaran 2019/2020 ternyata dapat meningkatkan prestasi belajar Bahasa Inggris materi teks deskriptif.
Penerapan Media Audio-Visual untuk meningkatkan kemampuan Listening Siswa Kelas VII UPT SMP Negeri 1 Tapung Hilir
Authors: Halimatusyakdiah  
Published: March 2024

Penelitian ini dilaksanakan di UPT SMP Negeri 1 Tapung Hilir di Kelas VII yang kemampuan siswanya untuk materi Mendengarkan Bahasa Inggris cukup rendah. Tujuan penulisan penelitian tindakan kelas ini adalah untuk mengetahui apakah model pembelajaran Audio-Visual dapat meningkatkan aktivitas dan prestasi belajar siswa. Metode pengumpulan datanya adalah observasi dan tes prestasi belajar. Metode analisis datanya adalah deskriptif baik untuk data kualitatif maupun untuk data kuantitatif. Hasil yang diperoleh dari penelitian ini adalah Audio-Visual dapat meningkatkan aktivitas dan prestasi belajar siswa. Ini terbukti dari hasil yang diperoleh pada Siklus I adalah 6,3 untuk prestasi belajar. Dari Siklus I ke Siklus II naik menjadi 7,9 untuk prestasi belajar. Kesimpulan yang diperoleh dari penelitian ini adalah model pembelajaran Audio-Visual dapat meningkatkan prestasi belajar.