bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Global Track Concept for Assessment of Engaging Hill-Sachs Defects in Anterior Shoulder Instability
Authors: Moroder Philipp , Akguen Doruk , Paksoy Alp , Gebauer Henry , Barthod-Tonnot Nicolas , Lupetti Mattia , Markova Viktoria , Zettinig Oliver , Parada Stephen , Karpinski Katrin 
Published: March 2024

Background: The glenoid track concept is used to determine preoperatively whether a Hill-Sachs defect is engaging or not. Currently, the glenoid track concept relies on measurements of bony structures as well as on the confines and elasticity of the rotator cuff as a reference point, which varies extensively among individuals and therefore limits the reliability and accuracy of this concept. Purpose: To evaluate the reliability of the global track concept, which determines the angular distance of the Hill-Sachs defect from the center of the articular surface of the humeral head as a new reference point with the help of an automated image analysis software and 3-dimensional analysis of the humeral head. Study Design: Controlled laboratory study. Methods: Computed tomography scans of 100 patients treated for anterior shoulder instability with different sizes of Hill-Sachs defects were evaluated manually by 2 orthopaedic surgeons independently using the software OsiriX as well as automatically by using a dedicated prototype software (ImFusion). Obtained manual and automated measurements included the Hill-Sachs length, Hill-Sachs width, and Hill-Sachs depth of the defect; the Hill-Sachs interval (HSI); and the glenoid width for the glenoid track concept, as well as the angular distance of the Hill-Sachs defect from the center of the articular surface of the humeral head (global track concept). The reliability of the different measurement techniques was compared by calculating intraclass correlation coefficients (ICCs). Results: There was a significant difference for all obtained parameters comparing manual and automatic measurements. For manually obtained parameters, measurements referring to bony boundaries (glenoid width, Hill-Sachs length, and Hill-Sachs width) showed good to excellent agreement (ICC, 0.86, 0.82, and 0.62, respectively), while measurements referring to soft tissue boundaries (HSI and glenoid track; ICC, 0.56 and 0.53, respectively) or not directly identifiable reference points (center of articular surface and global track) only showed fair reliability (ICC middle excursion, 0.42). When the same parameters were measured with the help of an automated software, good reliability for the glenoid track concept and excellent reliability for the global track concept in the middle excursion were achieved. Conclusion: The present study showed that the more complex global track measurements of humeral defects are more reliable than the current standard HSI and glenoid track measurements. However, this is only true when automated software is used to perform the measurements. Clinical Relevance: Future studies using the new proposed method in combination with an automated software need to be conducted to determine critical threshold values for defects prone to engagement.
Noninvasive and Reliable Quantification of Anteromedial Rotatory Knee Laxity: A Pilot Study on Healthy Individuals
Authors: Willinger Lukas , Runer Armin , Vieider Romed , Muench Lukas N. , Siebenlist Sebastian , Winkler Philipp W. 
Published: March 2024

Background: Anteromedial rotatory instability (AMRI) of the knee is a complex and severe condition caused by injury to the anterior cruciate ligament and/or the medial collateral ligament. Clinical studies dealing with AMRI are rare, and objective measurements are nonexistent. Purpose/Hypothesis: The objectives of this study were, first, to quantify anteromedial rotatory knee laxity in healthy individuals using a noninvasive image analysis software and, second, to assess intra- and interrater reliability and equivalence in measuring anteromedial knee translation (AMT). It was hypothesized that AMT could be reliably quantified using a noninvasive image analysis software. Study design: Cohort study; Level of evidence, 3. Methods: This prospective proof-of-concept study included healthy individuals aged 16 to 40 years with no history of knee injury or surgery. Three adhesive surface markers were placed on predefined landmarks on the medial side of the knee. Three independent investigators examined anteromedial rotatory knee laxity with an anterior drawer test in different tibial rotations (neutral tibial rotation, 15° of external tibial rotation, and 15° of internal tibial rotation). The entire examination of each knee was recorded, and AMT including the side-to-side difference (SSD) was assessed using a freely available and validated image analysis software (PIVOT iPad application). Group comparisons were performed using a 1-way analysis of variance with Bonferroni-adjusted post hoc analysis. Intraclass correlation coefficients (ICCs) were calculated to assess inter- and intrarater reliability of AMT measurements. Equivalence of measurements was evaluated using the 2 one-sided t-test procedure. Results: Anteromedial rotatory knee laxity was assessed in 30 knees of 15 participants (53% male) with a mean age of 26.2 ± 3.5 years. In all 3 raters, the highest AMT was observed in neutral tibial rotation (range of means, 2.2-3.0 mm), followed by external tibial rotation (range of means, 2.0-2.4 mm) and internal tibial rotation (range of means, 1.8-2.2 mm; P < .05). Intrarater reliability of AMT (ICC, 0.88-0.96) and SSD (ICC, 0.61-0.96) measurements was good to excellent and moderate to excellent, respectively. However, interrater reliability was poor to moderate for AMT (ICC, 0.44-0.73) and SSD (ICC, 0.12-0.69) measurements. Statistically significant equivalence of AMT and SSD measurements was observed between and within raters for almost all testing conditions. Conclusion: Anteromedial rotatory knee laxity could be quantified using a noninvasive image analysis software, with the highest AMT observed during neutral tibial rotation in uninjured individuals. Reliability and equivalence of measurements were good to excellent within raters and moderate between raters.
Effect of surface-modified incinerated sewage sludge ash as a reinforcing filler on the mechanical and thermal properties of polylactic acid composites
Authors: Sun Hao , Liu Lu , Hu Siyang , Wei Lingjun , Chen Haiying , Nan Huixing , Li Mingwei , Yan Dongshuai 
Published: March 2024

Biodegradable thermoplastic polylactic acid (PLA) has recently been limited in its broader development and application due to its high cost. Therefore, it is crucial to develop low-cost and high-performance PLA-based composites by adding fillers. In this study, surface-modified incinerated sewage sludge ash (M-OH-ISSA) was employed as a reinforcing filler in PLA to prepare PLA/M-OH-ISSA thermoplastic composites with varying M-OH-ISSA ratios (10–30 wt%), and the mold mechanism for the PLA/M-OH-ISSA composites was explored. The surface of incinerated sewage sludge ash (ISSA) was modified to improve interfacial adhesion by NaOH alkali treatment and KH570 silane grafting, which successfully grafted silane groups onto the surface of the ISSA and converted the surface from hydrophilic to hydrophobic, strengthening the compatibility between the ISSA and PLA. The effects of the M-OH-ISSA content on the mechanical and thermal properties of the PLA composites were investigated. The mechanical test results showed that the tensile and flexural properties of the 15 wt% M-OH-ISSA-filled PLA composites were excellent compared to those of pure PLA, with strengths of 33.67 MPa and 73.70 MPa, respectively, which are all 1.6 times greater than those of pure PLA. Morphological analysis via SEM indicated that the composites with 15 wt% M-OH-ISSA exhibited good adhesion between the M-OH-ISSA and the matrix. The thermal performance of the composites was determined by using differential scanning calorimetry (DSC) and thermogravimetric analysis (TG/DTG). The results showed that the crystallinity of the composites increased with increasing M-OH-ISSA content and that the thermal stability between 290°C and 400°C decreased slightly with increasing M-OH-ISSA. However, the composites have good thermal stability near 200°C and do not undergo thermal degradation if processed at this temperature. As a filler in composites, M-OH-ISSA can reduce PLA usage and improve polymer properties, applying PLA/M-OH-ISSA composites in packaging and 3D printing applications.
ANCA in patients with systemic lupus erythematosus. A cross sectional study in Brazilian patients and review of literature
Authors: Nisihara Renato , Vithoft Gabriela , Alencar Isabela , dos Santos Thiago Alberto F. G. , Skare Thelma Larocca 
Published: March 2024

Background Antineutrophil cytoplasmatic antibodies (ANCA) have been detected in patients with systemic lupus erythematosus (SLE). In this study, we investigated the presence of ANCA in a sample of Brazilian SLE patients and its possible associations with clinical and serological outcomes. Additionally, we reviewed the literature of on ANCA in SLE. Results The presence of ANCA was detected in 130 patients using indirect immunofluorescence (IIF). The test was positive in 29.9% of the cases (17.6% pANCA and 11.5% cANCA). Male sex and peripheral vasculitis were more prevalent in the ANCA-positive sample. cANCA was associated with lupus anticoagulant and pANCA had a positive association with peripheral vasculitis and a negative association with anti- SSB/La antibodies. In the 22 studies included in the literature review, a wide range of ANCA positivity was found (13% to 81.1% by IIF and 0 to 22.2% by ELISA). ANCA was associated with renal damage in the Asian population. Although other associations have been found in isolated studies, they were not consistently reported. Conclusions The ANCA prevalence found in this Brazilian sample was within the range reported in the literature and these autoantibodies were more frequent in males and in patients with vasculitis. The literature showed controversial results on the association between ANCA and SLE disease activity or clinical characteristics.
Salvage of brachiocephalic aneurysmatic fistulas, using ePTFE graft with a minimally invasive approach
Authors: Tamtekin Burak , Ersoy Güler Gülsen 
Published: March 2024

Background: In this study, we evaluated our surgical approach in requiring surgical treatment of brachiocephalic arteriovenous fistula (AVF) aneurysms for salvage of AVF. Methods: Between 2012 and 2022, 20 patients (16 men, 4 women; mean age 54.5 years) who were surgically treated for a brachiocephalic AVF aneurysm in our Cardiovascular Surgery Clinic were evaluated retrospectively. These 20 patients were operated on for aneurysm thrombosis and fistula failure in 16 patients, sudden rupture and severe bleeding in 3 patients, cosmetic reasons, and anxiety in 1 patient. Results: These aneurysms were ligated and divided from distal and proximal cephalic veins. Then, a 6 mm dialysis graft was interposed between the well-developed cephalic vein distal and proximal to the aneurysm with small skin incisions. All patients were taken to dialysis via this dialysis graft 24 h after the procedure without any problem. All patients were discharged after dialysis. After surgery, no catheterization or any other additional procedure was required for hemodialysis. No complications, such as infection, hematoma, neurological damage, or ischemia, were observed after the surgical procedure. The mean postoperative follow-up was 12 months. Conclusion: In brachiocephalic AVF aneurysms requiring surgical treatment, hemodialysis can be continued with a graft placed in the same arm in this technique.
Comparison of ultrasound guided supraclavicular subclavian vein versus infraclavicular subclavian/axillary vein catheterization: A systematic review and meta analysis
Authors: Hosur Ravikumar Rajathadri , Majage Siddhavivek , Prasanna Mrudula , Ray Bikash Ranjan 
Published: March 2024

Background: Subclavian vein cannulation is an important technique of central venous cannulation with a supraclavicular and an infraclavicular approach. There are randomized controlled trials (RCTs) which highlight the various differences between these two approaches when accessed via ultrasound. We undertook a meta-analysis to compare the ultrasound guided supraclavicular subclavian and the infraclavicular subclavian/axillary vein cannulation, keeping in mind that the infraclavicular approach may lead to cannulation of either subclavian/axillary vein. Methods: This meta-analysis encompassed studies that compared ultrasound-guided supraclavicular subclavian vein and infraclavicular subclavian/axillary vein. Binary outcomes were presented as odds ratios (OR), while continuous outcomes were presented as standardized mean differences (SMD) accompanied by 95% confidence intervals (95% CI). Potential trials meeting the eligibility criteria were sought from databases including PubMed, PubMed Central, The Cochrane Library, and EMBASE, covering the period from inception to April 30, 2023. Results: The analysis comprised a total of six randomized controlled trials (RCTs) and one retrospective observational study collectively involving 1812 patients. The first pass success rate for subclavian vein catheterization was found to be greater with the supraclavicular approach (OR = 1.91 [95% CI 1.04–3.50]; p = 0.0002; I2 = 77%). Moreover, the supraclavicular approach exhibited a significantly shorter catheterization time compared to the infraclavicular approach (SMD = −0.26 [95% CI −0.54 to 0.03]; p = 0.003; I2 = 73%). Notably, there was no substantial disparity in complication rates between the two approaches (OR = 0.66 [95% CI 0.35–1.24]; p = 0.20; I2 = 0%). Conclusion: Ultrasound-guided supraclavicular approach for subclavian vein catheterization is superior to the infraclavicular approach for subclavian/axillary vein catheterization, with higher first-pass success rates, shorter catheterization times. However, there were no differences in the complication rates.
Factors Associated With Precancerous Cervical Lesions in Human Immunodeficiency Virus–Infected Women: A Cross-Sectional Survey in Togo
Authors: Darré Tchin , Djiwa Toukilnan , Ladekpo Karell Josiane Ogniadé , M’Bortche Bingo K , Douaguibe Baguilane , Aboubakari Abdoul-Samadou , Ekouévi Didier Koumavi , Saka Bayaki 
Published: March 2024

Background: The burden of human immunodeficiency virus (HIV) in cervical cancer remains a major public health challenge in developing countries, like Togo. Precancerous lesions include all cellular abnormalities that have malignant potential that can develop into cancer. The objective of this study was to determine the prevalence and factors associated with precancerous cervical lesions in HIV-infected women in our context. Methods: A cross-sectional descriptive study was carried out from November 31, 2022, to January 31, 2023, in an HIV care center in Lomé (Non-Governmental Organization Espoir Vie Togo [NGO EVT] Grand-Lomé-Togo). Results: A total of 271 women were included with a mean age of 47.0 years and a standard deviation of 10.0 years, among whom 20.7% do not have any scholar education. Only 6.7% of them had previously performed cervical smear examinations. The prevalence of precancerous cervical lesions observed in people living with human immunodeficiency virus (PLHIV) was 11.4% with a 95% confidence interval (CI) of 5.0 to 15.4. Cytological abnormalities were marked by low-grade squamous intraepithelial lesion (LSIL) (5.1%), followed by the presence of atypical squamous cells of undetermined significance (ASCUS) (3.5%). A statistically significant association was found between parity and the presence of precancerous lesions ( P = .014). Conclusions: In this study, more than 1 out of 10 women living with HIV had precancerous cervical lesions, and parity was the factor associated. The implementation of a systematic screening program for precancerous cervical lesions and human papillomavirus (HPV) infection integrated into HIV care is necessary for early treatment.
Consequences of the Coronavirus disease 2019 pandemic on child and adolescent mental, psychosocial, and physical health: A scoping review and interactive evidence map
Authors: Bialy Liza , Elliott Sarah A , Melton Alison , Ali Samina , Scott Shannon D , Knisley Lisa , Hartling Lisa 
Published: March 2024

Effects of the Coronavirus disease 2019 (COVID-19) pandemic on children stem beyond immediate infectious and post-infectious risks. Our aim was to conduct a scoping review and produce an online Interactive Evidence Map (IEM) highlighting available literature around unintended effects of the pandemic on children’s and adolescents’ mental, psychosocial, and physical health. A search was run monthly in MEDLINE, PsycINFO, CENTRAL, and Cochrane COVID-19 Study Register from May 1st 2021 through April 30th 2022. All articles involving children and adolescents under 18 years of age relating to any unintended mental, psychosocial, and physical health consequences of the pandemic and resultant restrictions were included. Data were extracted and topics categorized, with corresponding data uploaded into EPPI-Reviewer and transferred to EPPI-Mapper for visualization. A total of 14,555 citations were screened and 826 (6%) articles included. Most articles reported on mental health outcomes, particularly anxiety ( n = 309, 37%) and depression ( n = 294, 36%). Psychosocial outcomes related to lockdowns such as loneliness ( n = 120, 15%) and impact on adolescent relationships with others ( n = 149, 18%) were also reported. Fewer articles examined physical consequences, but those that did mostly focused on child abuse ( n = 73, 9%). Overall, currently mapped literature focuses on consequences related to mental health outcomes such as anxiety and depression.
Design and evaluation of thermal insulation of air layer for sentry building envelopes
Authors: Chang Zhu , Yin Haiguo , Han Yuekun , Liang Linfeng 
Published: March 2024

The prevalence of small-scale structures, such as sentry buildings, has become widespread, with many of these buildings exposed to the outdoor environment and exhibiting suboptimal thermal insulation in their envelopes. Through a comprehensive study of outdoor disturbances, the most unfavourable envelope was identified. In light of this finding, we have designed static air layer sentry buildings (SAL-SB) and dynamic air layer sentry buildings (DAL-SB). The study conducted experiments and numerical simulations to evaluate the impact of air layer thickness, vent opening forms, and inlet velocities on the thermal insulation of sentry buildings. The results showed that both the SAL and DAL effectively improved thermal insulation, and a thickness of 25 cm has been found to offer the best thermal insulation. However, considering the balance between thermal insulation and cost-effectiveness, a thickness of 15 cm is recommended. Additionally, for DAL, an inlet velocity of 3 m/s is the threshold for switching the heat transfer direction on the roof. These findings provide novel insights into enhancing the thermal environment.
Effectiveness of a Multidisciplinary Limb Preservation Program in Reducing Regional Hospitalization Rates for Patients With Diabetes-Related Foot Complications
Authors: Manji Ali , Basiri Reza , Harton Francois , Rommens Kenton , Manji Karim 
Published: March 2024

Objective This study evaluated the toe and flow model (TFM), a limb preservation program led by podiatric surgeons in Alberta, Canada, for its impact on hospitalization rates and length of stay (LOS) in patients with diabetic foot complication (DFC). Diabetes, a leading cause of non-traumatic lower extremity amputations (LEAs) in Canada, often results in diabetic foot ulcers (DFUs), a major cause of infection, amputation, and hospitalization. TFM has reportedly reduced amputation rates by 39% to 56%. Methods The study analyzed Alberta's health database from 2007 to 2017, focusing on diabetes patients aged 20 and above. It included patients with various DFCs and compared outcomes in regions using TFM and standard of care (SOC). The study also examined data from two major cities, one with TFM and the other without, including rural referrals to Calgary and Edmonton. The data were normalized for the diabetic population and analyzed using a standard Student’s t-test. Results TFM regions showed significantly lower hospitalization rates ( p = 1.22E-12) than SOC regions. Over 11 years, TFM maintained lower average and median LOS by 0.13 and 0.26 days, respectively. TFM access reduced hospitalization risk by up to 30%, and patients in TFM regions had a 21% shorter LOS compared to SOC regions. Conclusion Despite similar demographics and healthcare systems, the TFM region benefited from a dedicated multidisciplinary program and comprehensive limb preservation services. The study shows that TFM effectively reduces hospitalizations and LOS for DFCs, with significantly better outcomes in the TFM region than in SOC regions.
Novel Image-Guided Percutaneous Lung Tissue Excision Device With Integrated Sealing of Blood Vessels and Airways: An In Vivo Preclinical Study
Authors: Salazar Jorge E. , Fischel Richard , Bueche Kenneth M. , Samra Kian , Gonzalez Laura , Nathan Joanna C. , Lu Carolyne , Rodriguez Joanna , Nguyen Steven , Cohn William E. , Boyle Edward 
Published: March 2024

Objective: This study evaluated the efficacy of the Minimally Invasive Targeted Resection (MiTR) device, a novel electrosurgical instrument that allows for targeted excision of a lung abnormality while using bipolar radiofrequency (RF) energy to seal blood vessels and airways. Methods: The MiTR system was evaluated in 7 acute and 2 chronic porcine (7-day) models to evaluate the efficacy of tissue excision with bipolar RF sealing of blood vessels and airways and application of an autologous blood patch into the excised tissue cavity. Air leak was recorded for all evaluations. The study was approved by the institutional ethical board. Results: Nineteen lung tissue samples, measuring 2.5 cm long × 1.2 cm diameter, were excised. In 8 of 9 animals (89%), hemostasis and pneumostasis were observed visually at the completion of the procedure. In 2 of 2 chronic animals (100%), hemostasis and pneumostasis persisted for the 7-day observation period. Histologic examination of the excised samples showed preservation of the core parenchymal architecture without evident tissue damage of the samples that would impair pathologic analysis. Conclusions: Percutaneous resection of targeted lung tissue with the MiTR system demonstrated hemostasis and pneumostasis while obtaining a histologically intact sample. After regulatory approval, the use of this device could offer more tissue for analysis than a transthoracic needle biopsy or bronchoscopy and a far less invasive alternative to video-assisted thoracic surgery or thoracotomy. This may also expand patient and physician options for the early diagnosis and treatment of lung cancer.