bluuebunny/crossref_metadata_2025_split huggingface dataset:
Decoding submergence tolerance in Prunus persica: Integrated transcriptomic and metabolomic acclimations of antioxidant system, cell wall dynamics, and hormonal signaling
Authors: Ateeq Muhammad , Zhang Dongmei , Xiao Jinping , Zhang Huiqin , Shen Xingyi , Meng Jian , Yang Jinzhi , Alam Shariq Mahmood , Kaleem Muhammad Mohsin , Khan Muhammad Abbas , Zhu Kaijie , Li Guohuai , Liu Junwei 
Published: February 2025

Abstract
Low oxygen stress (hypoxia) induced by submergence significantly impairs respiration in fruit trees, leading to reduced yield and, in extreme cases, tree mortality. While extensive research has focused on the root responses of peach trees to waterlogging, the mechanisms underlying leaf responses to complete submergence remain poorly understood. In this study, both transcriptomic and metabolic approaches were employed to explore the differential submergence tolerance between two peach cultivars: 'Dongxi Xiaoxian' (DX), which exhibits tolerance, and 'Hujing Milu' (HM), which is sensitive. Compared to HM, DX leaves experienced less decline in leaf verdancy, chlorophyll, and carotenoid content under submergence. DX leaves also showed enhanced antioxidant activities of ROS scavengers and reduced levels of H2O2 and MDA, correlating with improved tolerance. Transcriptomic analysis revealed significant alterations in the expression of genes involved in photosynthesis, glycan biosynthesis, and α-linolenic acid metabolism between the two cultivars. Key metabolites, including sugars (sorbitol and sucrose), amino acids (phenylalanine and L-norvaline), cell wall polysaccharides (lignin and pectin), and plant hormones (jasmonic acid and salicylic acid), were identified as critical for DX's superior submergence tolerance. These findings elucidate the mechanisms of peach leaf tolerance to submergence, providing insights into potential strategies for genetic improvement aimed at enhancing hypoxia resistance in fruit trees.
Latent and Manifest Tuberculosis in Patients with Rheumatoid Arthritis Treated with Anticytokine Therapy
Authors: Skamlova Martina , Kmecova Zlata , Kanianska Michaela , Barekova Ludmila , Rybar Ivan 
Published: February 2025

Abstract

Objectives
The aim of study was to determine the occurrence and risk factors of latent (LTBI) and manifest tuberculosis infection (MTBI) in patients with rheumatoid arthritis (RA) treated with biologic and targeted-synthetic disease-modifying drugs (b/tsDMARDs) in Slovakia.

Methods
Retrospective observational study included 689 patients with moderate-to-severe RA treated with b/ts DMARDS, screened for LTBI.

Results
The prevalence of of LTBI before the initiation of b/tsDMARDs was 10.3%. During subsequent treatment with b/tsDMARD, LTBI was diagnosed in another 12% of remaining patients (17,9 cases/1000 patient-years of treatment). Patients diagnosed with LTBI were older (64.2 ± 12.4 vs 60.9 ± 12.8, p = 0.02), more often treated with TNF inhibitors (p = 0.032), and had a longer duration of bDMARD/tsDMARD therapy (83.7 ± 44.1 versus 49.2 ± 40.2 months, p < 0.001). As many as 73 of 74 patients with LTBI were treated with the first bDMARD/tsDMARD (p < 0.001). Risk factors associated with LTBI were first bDMARD/tsDMARD (OR = 32.5 (95% CI: 6.3–609.6), p = 0.001) and duration of anticytokine treatment (OR 1.013 (CI: 1.007–1.019), p < 0.001). MTBI was diagnosed with an incidence of 0.3% (2 of 689 patients). The proportion of tuberculosis manifestation in previously diagnosed LTBI cases was 1.4%.

Conclusion
LTBI can affect up to 21% of RA patients treated by b/tsDMARDs. Treatment with the initial bDMARD, TNF inhibition, and the duration of anticytokine therapy have been identified as risk factors for LTBI occurence. The incidence of MTBI is 1.4%, which demonstrates the high effectiveness of chemoprophylaxis in preventing the activation of tuberculosis.
The economics of occupational health and safety
Authors: Belzer Michael H. , Quinlan Michael Garry 
Published: February 2025

AbstractThis special Themed Collection of The Economic and Labour Relations Review examines the ‘Economics of Occupational Health and Safety’ (OHS). The economics of OHS looks at how economic structures and incentives, including labour markets and production processes, influence the health and wellbeing of workers and the communities where they live. It is a large and diverse subject that has been viewed from multiple different lenses. This thematic issue can only touch on some of these but will remind readers how economic incentives and industrial competitive pressures affect OHS. This editorial will take the form of an article which explores some of these intersections and places them in a wider context. To do this, the economics of OHS will not only be examined in terms of economic welfare and microeconomics at the industry and workplace level, but also from an historical perspective, as well as the intersection of these levels, thus providing a useful framework to shape research and discussion.
Dynamical Diophantine approximation and shrinking targets for
$C^{1}$
weakly conformal IFSs with overlaps
Authors: DAVIAUD EDOUARD 
Published: February 2025

Abstract
In this article, we extend, with a great deal of generality, many results regarding the Hausdorff dimension of certain dynamical Diophantine coverings and shrinking target sets associated with a conformal iterated function system (IFS) previously established under the so-called open set condition. The novelty of the result we present is that it holds regardless of any separation assumption on the underlying IFS and thus extends to a large class of IFSs the previous results obtained by Beresnevitch and Velani [A mass transference principle and the Duffin–Schaeffer conjecture for Hausdorff measures. Ann. of Math. (2)164(3) (2006), 971–992] and by Barral and Seuret [The multifractal nature of heterogeneous sums of Dirac masses. Math. Proc. Cambridge Philos. Soc.144(3) (2008), 707–727]. Moreover, it will be established that if S is conformal and satisfies mild separation assumptions (which are, for instance, satisfied for any self-similar IFS on

$\mathbb {R}$

with algebraic parameters, no exact overlaps and similarity dimension smaller than

$1$

), then the classical result of Hill–Velani regarding the shrinking target problem associated with a conformal IFS satisfying the open set condition (and for which the Hausdorff measure was later computed by Allen and Barany [On the Hausdorff measure of shrinking target sets on self-conformal sets. Mathematika67 (2021), 807–839]) can be extended.
Law and History in Angola: The Collection of Court Cases in the Benguela District Court (1850–1945)
Authors: Candido Mariana P. , Dias Paes Mariana A. , de Matos Ngãla Juelma 
Published: February 2025

Abstract
Court records are rich primary sources to social historians, and much attention has been paid to these types of documents in different African territories. In most cases only summaries have survived, but in Angola complete proceedings have been preserved. Examining the court case collection available at the Benguela District Court, we discuss its strengths and methodological challenges, and present possible themes for future research. The use of these records reveals new aspects of the Angolan past, including more information on local norms and the ability of African women to use the Portuguese courts.
Characterization of the complete mitochondrial genomes of Corynosoma bullosum (von Linstow, 1892) and C. evae Zdzitowiecki, 1984 (Acanthocephala: Polymorphida), and the phylogenetic implications
Authors: Xie Y.-Y. , Chen H.-X. , Kuzmina T. A. , Lisitsyna O. , Li L. 
Published: February 2025

Abstract
Species of the genus Corynosoma (Acanthocephala: Polymorphida) mainly parasitize marine mammals and rarely marine birds, and are of veterinary and medical importance due to causing corynosomiasis in wildlife and humans. However, the current knowledge of the mitochondrial genomes and mitogenomic phylogeny of this group remains very insufficient. In the present study, the complete mitochondrial genomes of C. bullosum (von Linstow, 1892) and C. evae Zdzitowiecki, 1984 were sequenced and annotated for the first time. Both mitogenomes comprise 12 protein-coding genes (missing atp8), 22 tRNA genes, and 2 ribosomal RNAs (rrnS and rrnL), plus 2 non-coding regions (NCR1 and NCR2). Corynosoma bullosum has the largest mitogenome (14,879 bp) of any polymorphid species reported so far, while C. evae has the smallest (13,947 bp), except for Sphaerirostris lanceoides (Petrochenko, 1949). Comparative mitogenomic analysis also revealed the presence of distinct discrepancies in A + T content and gene rearrangement across the families Polymorphidae, Centrorhynchidae, and Plagiorhynchidae. Moreover, phylogenetic analyses based on the concatenated amino acid sequences of 12 protein-coding genes strongly supported the monophyly of the order Polymorphida and a close affinity between the families Polymorphidae and Centrorhynchidae in Polymorphida. The present mitogenomic phylogeny provides additional evidence for a sister relationship between the genera Corynosoma and Bolbosoma and demonstrated that C. evae has a closer relationship with C. villosum than C. bullosum in the genus Corynosoma.
Greater sensitivity to communication partners’ perspectives in children learning a second language at school
Authors: Agostini Valeria , Apperly Ian A. , Krott Andrea 
Published: February 2025

Abstract
Early learning of a second language at home has been found to be beneficial for children’s cognitive development, including their ability to ascribe mental states to others. We investigated whether second language learning in an educational setting can accelerate children’s sensitivity to a communication partner’s perspective and whether the amount of exposure to second language education makes a difference. We tested three groups of English monolingual four-five year old children with varying language exposure at the beginning of their first year at primary school and 24 weeks later. Children attending bilingual schools and children with weekly second language lessons exhibited similar accelerated development of communicative perspective-taking skills compared to children without second language provision. Such advances were not related to other cognitive advances. Thus, limited foreign language teaching might boost young children’s development in communicative perspective-taking skills, providing an enhanced basis for their social competence development.
Recognising differentiated affectedness within a global demos: promoting the democratic legitimacy of the UNFCCC
Authors: Sharman Nicola 
Published: February 2025

Abstract
This article seeks to understand the evolving democratic legitimacy demands of the United Nations Framework Convention on Climate Change (UNFCCC) by reflecting on the challenges of catering to a globally affected public and enhanced participation opportunities given to some highly affected groups. It argues that the principle of democratic equality at a global scale fails to take account of inequities in affectedness and power within the demos and, instead, an approach that strives towards a principle of proportionality based on degrees of affectedness could enhance the UNFCCC’s democratic legitimacy. This builds on existing scholarship identifying a turn to an affectedness paradigm in international institutions more generally and the emerging influence of affected peoples organisations, characterised by the more direct forms of representation they facilitate and emphasis placed on the affectedness of their constituents to claim recognition and influence. The normative appeal of giving enhanced participatory opportunities to those most affected by climate governance is weighed against its challenges and risks. It is concluded that, despite conceptual and practical difficulties connected to the subjective nature of affectedness, a pragmatic approach that treats such a proportionality principle as a democratic ideal to be strived towards could have a legitimising effect on the UNFCCC.
Sensitivity of Pearl Millet (Pennisetum glaucum [L.] R. Br.) Parental Lines to POST Herbicides: Clethodim, Quizalofop-P-ethyl, Imazamox and Nicosulfuron
Authors: Tugoo Midhat Z. , Kumar Vipan , Ramalingam Ajay Prasanth , Parray Sabreena A. , Serba Desalegn D. , Prasad P.V. Vara , Perumal Ramasamy 
Published: February 2025

Abstract
Pearl millet is a climate-resilient grain and forage crop. Weeds pose a major constraint to its successful production. Limited herbicide options for grass weed control in pearl millet is a serious problem. The objectives of this study were to 1) evaluate the sensitivity of pearl millet parental lines to POST-applied clethodim (136 g ai ha-1), quizalofop-p-ethyl (QPE) (77 ai g ha-1), imazamox (52 g ai ha-1) and nicosulfuron (70 g ai ha-1), and 2) characterize the sensitivity of selected lines to imazamox and nicosulfuron. A total of 56 parental lines were tested. Three lines with low sensitivity to imazamox (ARCH35R, 45R, and 73R), two to nicosulfuron (ARCH45R and 73R), one line with high sensitivity (ARCH21B), and a susceptible sorghum (SOR) hybrid (P84G62) to both herbicides were characterized. All parental lines were sensitive to clethodim and QPE (only four lines showed 2 to 12% survival with 90 to 95% injury at 21 d after application [DAA]). However, all parental lines showed variable sensitivity to imazamox and nicosulfuron (70 to 100% survival with 5 to 70% visible injury and shoot dry biomass reduction at 21 DAA). Dose-response assays revealed that ARCH35R, 45R, and 49R had 7.7 to 12.2 and 3.2- to 12.2-fold reduced sensitivity to imazamox compared to the ARCH21B and SOR, respectively. Similarly, ARCH45R and 49R had 2.5 to 6.0 and 1.5- to 3.7-fold reduced sensitivity to nicosulfuron compared to ARCH21B and SOR, respectively. These findings confirm the first report of reduced sensitivity to imazamox and nicosulfuron among pearl millet lines, suggesting their potential use for in-season grass weed control.
Resistance Profile of Glufosinate-Resistant Palmer amaranth Accessions and Herbicide Options
Authors: Carvalho-Moore Pâmela , Norsworthy Jason K. , Souza Maria C. C. R. , Barber L. Tom , Bonilha Piveta Leonard , Meiners Ingo , Porri Aimone 
Published: February 2025

Abstract
Glufosinate resistance was previously confirmed in three Palmer amaranth accessions from Arkansas (MSR1, MSR2, and CCR). Greenhouse screening results suggested the presence of multiple herbicide resistance. Therefore, this study aimed to determine the postemergence resistance profile of three glufosinate-resistant Palmer amaranth accessions from Arkansas. Field experiments were also conducted to assess preemergence (PRE) and postemergence (POST) herbicide options to control the accession with the highest glufosinate resistance level (MSR2). A dose-response assay with the three resistant accessions and two susceptible standards was conducted with the herbicides 2,4-D, atrazine, dicamba, diuron, fomesafen, glyphosate, imazethapyr, and mesotrione. The PRE and POST field experiments with MSR2 evaluated fifteen and sixteen single active ingredients, respectively. The previously described Palmer amaranth accessions carrying glufosinate resistance were also confirmed resistant to six other POST herbicides: 2,4-D, diuron, fomesafen, glyphosate, imazethapyr, and mesotrione. CCR is also resistant to dicamba. Therefore, accessions MSR1, MSR2, and CCR have evolved resistance to POST herbicides pertaining to seven sites of action. A shift towards increased tolerance to atrazine has been observed among all resistant accessions as well. Overall, field PRE treatments with atrazine, pyroxasulfone, or trifludimoxazin obtained the highest MSR2 control levels at all evaluation times and the lowest number of seedlings emerging at 3 and 6 weeks after treatment. In the POST experiment, only paraquat obtained MSR2 control levels above 90% at all ratings. The lowest number of alive MSR2 plants was obtained in POST treatments with paraquat or trifludimoxazin. Fields near where glufosinate resistance has been confirmed in Palmer amaranth will likely demand a more diverse and proactive management strategy relying on combinations of chemical, cultural, and mechanical control tactics. Future efforts should focus on sequential applications and mixture, the elucidation of all resistance mechanisms in the evaluated accessions, and soil applied dose-response.
The Scaling of MCS, Non‐MCS, and Total Extreme Precipitation With Temperature Over the Central United States
Authors: Hu Huancui , Leung L. Ruby , Sun Xiaoming , Wang Guiling 
Published: February 2025

AbstractWhile extreme precipitation is expected to increase in a warming climate, its scaling with temperature at weather timescales often produces puzzling results. Here, we focus on the summer months over the central U.S. to investigate the scaling of extreme precipitation intensity (EPI) with local temperature and determine the contribution of mesoscale convective systems (MCSs) to the EPI scaling. Using an observational data set that differentiates precipitation associated with MCS and non‐MCS storms, we find that MCS storms contribute to 70% of EPI samples at temperatures lower than 298 K where EPI increases with temperature. However, at temperatures of 298–305 K, MCSs' contribution to EPI decreases as the predominant storm type shifts from MCS to non‐MCS storms, causing EPI to decrease with temperature due to the weaker rainfall intensity associated with non‐MCS storms compared with MCS storms. Our findings underscore the important role of different storm types in affecting the EPI scaling relationships.
High-fidelity light-field display with enhanced information utilization by modulating chrominance and luminance separately
Authors: Zhang Zhaohe , Yu Xunbo , Gao Xin , Liu Boyang , Wang Hanbo , Gao Chao , Hao Zeyu , Zhao Ruiang , Sang Xinzhu 
Published: February 2025

Abstract
Light-field displays typically consist of a two-dimensional (2D) display panel and a light modulation device. The 2D panel presents synthesized parallax images, with the total information content of the three-dimensional (3D) light field dictated by the panel’s total resolution. Angular resolution serves as a critical metric for light-field displays, where higher angular resolution correlates with a more realistic 3D visual experience. However, the improvement of angular resolution is typically accompanied by a reduction in spatial resolution, due to the limitations of the 2D display panel’s total resolution. To address this challenge, a light-field display method with enhanced information utilization is introduced, achieved through the independent modulation of chrominance and luminance. A static light-field image display system is proposed to verify the feasibility of this method. The system employs a bidirectional angular modulation grating (BAMG) and a collimated light source (CLS) to create uniformly distributed viewpoints in space. A luminance modulation film (LMF) and a chrominance modulation film (CMF) are utilized to modulate the light-field information, with chrominance and luminance synthesized images printed at pixel densities of 720 pixels per inch (PPI) and 8000 dots per inch (DPI), respectively, to align with the differential sensitivities of the human visual system. In the experiment, the proposed display system achieves a full-parallax, high-fidelity color display with a 98.2° horizontal and 97.7° vertical field of view (FOV). So, the light-field display method of modulating chrominance and luminance separately has been proven to achieve high-fidelity display effects.
Horizontal transfer of accessory chromosomes in fungi – a regulated process for exchange of genetic material?
Authors: Habig Michael , Patneedi Satish Kumar , Stam Remco , De Fine Licht Henrik Hjarvard 
Published: February 2025

Abstract
Horizontal transfer of entire chromosomes has been reported in several fungal pathogens, often significantly impacting the fitness of the recipient fungus. All documented instances of horizontal chromosome transfers (HCTs) showed a marked propensity for accessory chromosomes, consistently involving the transfer of an accessory chromosome while other chromosomes were seldom, if ever, co-transferred. The mechanisms underlying HCTs, as well as the factors regulating the specificity of HCTs for accessory chromosomes, remain unclear. In this perspective, we provide an overview of the observed propensity in reported cases of horizontal chromosome transfers. We hypothesize the existence of a signal that distinguishes mobile, i.e., horizontally transferred, accessory chromosomes from the rest of the donor genome. Recent findings in Metarhizium robertsii and Magnaporthe oryzae, suggest that a mobile accessory chromosome may contain putative histones and/or histone modifiers, which could generate such a signal. Based on this, we propose that mobile accessory chromosomes may encode the machinery required for their own horizontal transmission, implying that HCT could be a regulated process. Finally, we present evidence of substantial differences in codon usage bias between core and accessory chromosomes in 14 out of 19 analysed fungal species and strains. Such differences in codon usage bias could indicate past horizontal transfers of these accessory chromosomes. Interestingly, HCT was previously unknown for many of these species, suggesting that the horizontal transfer of accessory chromosomes may be more widespread than previously thought, and therefore an important factor in fungal genome evolution.
Breakage fusion bridge cycles drive high oncogene number with moderate intratumoural heterogeneity
Authors: Raeisi Dehkordi Siavash , Wong Ivy Tsz-Lo , Ni Jing , Luebeck Jens , Zhu Kaiyuan , Prasad Gino , Krockenberger Lena , Xu Guanghui , Chowdhury Biswanath , Rajkumar Utkrisht , Caplin Ann , Muliaditan Daniel , Gnanasekar Aditi , Coruh Ceyda , Jin Qiushi , Turner Kristen , Teo Shu Xian , Pang Andy Wing Chun , Alexandrov Ludmil B. , Chua Christelle En Lin , Furnari Frank B. , Maciejowski John , Paulson Thomas G. , Law Julie A. , Chang Howard Y. , Yue Feng , DasGupta Ramanuj , Zhao Jean , Mischel Paul S. , Bafna Vineet 
Published: February 2025

Abstract
Oncogene amplification is a key driver of cancer pathogenesis. Both breakage fusion bridge (BFB) cycles and extrachromosomal DNA (ecDNA) can lead to high oncogene copy numbers, but the impact of BFB amplifications on intratumoral heterogeneity, treatment response, and patient survival remains poorly understood due to detection challenges with DNA sequencing. We introduce an algorithm, OM2BFB, designed to detect and reconstruct BFB amplifications using optical genome mapping (OGM). OM2BFB demonstrates high precision (>93%) and recall (92%) in identifying BFB amplifications across cancer cell lines, patient-derived xenograft models, and primary tumors. Comparisons using OGM reveal that BFB detection with our AmpliconSuite toolkit for short-read sequencing also achieves high precision, though with reduced sensitivity. We identify 371 BFB events through whole genome sequencing of 2557 primary tumors and cancer cell lines. BFB amplifications are prevalent in cervical, head and neck, lung, and esophageal cancers, but rare in brain cancers. Genes amplified through BFB exhibit lower expression variance, with limited potential for regulatory adaptation compared to ecDNA-amplified genes. Tumors with BFB amplifications (BFB(+)) show reduced structural heterogeneity in amplicons and delayed resistance onset relative to ecDNA(+) tumors. These findings highlight ecDNA and BFB amplifications as distinct oncogene amplification mechanisms with differing biological characteristics, suggesting distinct avenues for therapeutic intervention.