bluuebunny/crossref_metadata_2025_split huggingface dataset:
Evaluation of Efficacy of Different Plating Systems in ZMC Fractures: An Original Research
Authors: Abhishek MP , Sikha John R. , Pal Arvind K. , Gelada Kalyani , Sethi Sanjana , Sameer Kumar Naik Banavath S. S. R. , Tiwari Rahul V. C. 
Published: February 2024

ABSTRACT

Objective:
This study’s objective was to assess and contrast the performance of several plating techniques in the treatment of zygomaticomaxillary complex (ZMC) fractures. Group A (Microplate System), Group B (Titanium Mesh System), and Group C (Absorbable Plate System) plating systems were the ones that were studied.

Materials and Methods:
With 10 patients in each group, a retrospective analysis of 30 patients with ZMC fractures was done. The following information was gathered: fracture reduction, stable fixation, complications, and patient satisfaction. Analysis was done on patient-reported outcomes, surgical outcomes, and demographic factors.

Results:
Group B (Titanium Mesh System) came in second with rates of 70% and 80%, respectively, while Group A (Microplate System) showed the highest rates of fracture reduction (90%) and stable fixation (100%). For fracture reduction and stable fixation, Group C (Absorbable Plate System) demonstrated rates of 80% and 90%, respectively. For Groups A, B, and C, the complication rates were 20%, 30%, and 10%, respectively. For Groups A, B, and C, the patient satisfaction levels were 90%, 80%, and 70%, respectively.

Conclusion:
According to the results, the Microplate System (Group A) is better than the Titanium Mesh System (Group B) and the Absorbable Plate System (Group C) in terms of fracture reduction and stable fixation when treating ZMC fractures. All plating systems had acceptable complication rates, and overall patient satisfaction ratings were high. Fracture features and patient-specific considerations should be taken into account while making individualized treatment options.
Comparative Evaluation of Different Post and Core Systems in Maxillary Molar Endodontic Treatments: An Original Study
Authors: Motru Suneetha , Sachdeva Harmeet Singh , Dutta Queentaj , Dewan Harisha , Late Laxmikant , Kapur Ishita 
Published: February 2024

ABSTRACT

Background:
Maxillary molar endodontic treatments require the right post and core system. This study tested cast metal, glass fiber with composite resin, carbon fiber with composite resin, and zirconia post and core materials.

Materials and Methods:
Sixty removed human maxillary teeth were randomly divided into four post and core material groups (n = 15 per group). The teeth acquired their post and core system after normal endodontic treatment. Fracture resistance, cyclic fatigue resistance, and microleakage analyses were statistically assessed.

Results:
The zirconia post and core material had the highest fracture resistance (mean: 900 N), followed by carbon fiber with composite resin, cast metal, and glass fiber with composite resin. Zirconia had the highest mean cycles to failure (120,000), followed by carbon fiber with composite resin (100,000), cast metal (110,000), and glass fiber with composite resin (90,000). Zirconia had the lowest mean microleakage score (1.8), and glass fiber with composite resin, the highest (3.0).

Conclusion:
The zirconia post and core material outperformed the others in fracture resistance, cyclic fatigue resistance, and sealing. The cast metal has better fracture and cycle fatigue resistance than glass fiber with composite resin. These findings help doctors choose maxillary molar endodontic post and core materials.
Efficacy of Various Herbal Preparations Against Oral Candida: A Lab-Based Study
Authors: Karni Prashant A. , Muraleedharan Aparna , Bhandary Srikala , Mujoo Sheetal , Maini Anuj Paul , Chaturvedi Mudita 
Published: February 2024

ABSTRACT

Aim:
This research was done to analyze the effectiveness related to herbal chemicals in tackling candidiasis.

Materials and Methods:
Grounded and ethanol-extracted residues of plants like Avicennia marina, Fagonia indica, Portulaca oleracea, Lawsania inermis, Ziziphus spina, Asphodelus tenuifolius, and Salvadora persica were used in the study. The extract was used against candida species, after which the antibacterial as well as cytotoxicity toward the former were evaluated.

Results:

L. inermis and P. oleracea with minimal inhibitory concentration of approx. 10 cenmL had an increased activity against candida species. The preparations of these plants acted against Candida albicans during its stages related to pathogenesis during biofilm production. Superadded infections like in case of bacterial infections along with candida can be difficult to cure. On human RBCs, these plant preparations had no toxicity at their minimum inhibitory concentration level.

Conclusion:
We concluded that, as far as being anti-candida and acting against MDR bacterial infections, preparations of plants were effective as an alternative to allopathic drugs.
Evaluation of Crestal Bone Levels using Simvastatin as an Adjuvant Around Immediate Implants – A Clinico Radiographic Study
Authors: Betha Hymasree , Rajmohan M. , Thakkar Radhika , Surya Bezgam R. , Shetty Manoj , Sankla Puja , Tiwari Rahul 
Published: February 2024

ABSTRACT

Objective:
Simvastatin was used as an adjuvant medication in this clinico-radiographic investigation to assess the impact on crestal bone levels around immediate implantation.

Materials and Methods:
A randomized controlled trial with 50 patients who needed an implant placed right away was done. Simvastatin was used as an adjuvant in groups ((Group A), whereas group (Group B)) served as the control group for the participants. At baseline and during follow-up visits, clinical measures such as probing depth (PD) and bleeding on probing (BOP) were measured. At baseline and 12 weeks, radiographic measurements of crestal bone levels were taken.

Results:
At 12 weeks, Group A demonstrated a significantly lower PD and BOP than did Group B. Furthermore, at 12 weeks, Group A showed greater crestal bone preservation than did Group B. The results of the statistical analysis showed that the two groups were significantly different.

Conclusion:
The results of this study indicate that simvastatin use as an adjuvant medication after immediate implant insertion contributes to better clinical outcomes and greater crestal bone preservation. Simvastatin may be helpful in increasing bone regeneration, decreasing inflammation, and soft tissue healing. These findings demonstrate how simvastatin may be used as an additional therapy to enhance the effectiveness of rapid implant implantation operations.
Assessment of the Peripheral Venous Cannulation in a Teaching Hospital: A Prospective Study
Authors: Lissy Ben Bella , Yeshwanth Peela Sai , Gopi Kodali , Nelson Anish , Thakkar Smit , Sri Sai Jeevana Mandadi 
Published: February 2024

ABSTRACT

Introduction:
In today’s healthcare environment, peripheral venous cannulations are frequently performed procedures. Bloodstream infections could occur as a result of the intrusive operation. Peripheral venous cannulas should be inserted and managed according to specific rules. This study compared these standards to the peripheral venous cannulation procedure and results at a teaching hospital institution.

Materials and Methods:
This study investigated the procedure and results of peripheral venous cannulation in a teaching center using a prospectively completed audit loop study. The “Royal College of Nursing’s criteria for infusion therapy” is one such set of recommendations. After the first phase of the observations, the audit was conducted. Later, after 4 months based on the recommendations, the personnel received training on a variety of cannulation-related topics and the second set of observations for the cannulations was performed. Both observations were made and compared for significance that was considered at. 05 using the ANOVA.

Results:
During the first phase of the research, 212 cannulations were made, and 314 were made for the second phase to be audited. In the reaudit compared with the initial audit, there was a statistically substantial surge in documentation, cannula cleansing, glove use, suitable site selection, and hand cleanliness, according to comparative exploration. Moreover, there was a statistically substantial decline in recannulations.

Conclusion:
Even though peripheral intravenous cannulation is a straightforward process, if done incorrectly, it might have serious side effects. Such techniques’ auditing reveals performance flaws. Reaudit results reveal a noticeable increase in performance and outcome following proper personnel retraining.
Vitamin D Levels Assessment among the Neonates with and without Seizures: A Single Center Cross-Sectional Study
Authors: Prusty Nilamadhab , Peela Sai Y. , Manaf Haifa , Thakkar Smit , Yanamadala Yaswanthi , Shashank Chapala 
Published: February 2024

ABSTRACT

Introduction:
The impact that vitamin D (vit D) has on a variety of medical conditions like diabetes, cardiovascular, oncological, and central nervous system disorders has been a topic of interest for many years now. It is well-known that vit D deficiency is substantially more common in epileptics than in healthy subjects. The current research was piloted to analyse the vit D levels of the blood in newborns with seizures, as well as mothers’ vit D status included subjects.

Materials and Methods:
A cross-sectional examination was piloted at a tertiary care center, which had a neonatal intensive care unit (NICU). The subjects were neonates and their mothers. The levels of vit D were measured in term and late preterm newborns who had been brought to the NICU with convulsions. Term or late preterm infants who were healthy and hospitalized in the same hospital’s postnatal unit as their mothers served as the controls for the study. Demographics, as well as the vit D levels of both the neonate and the mother, were estimated and compared and evaluated for any significance, keeping significance at less than 0.05.

Results:
Of the 72 neonates included, they were similarly distributed between the epileptic (37) and healthy subjects. (40) The mothersy subjects.cluded, they were sim D levels averaged 15.11 ded, they were similarly distributed b D levels of their newborns were 13.26 ± 5.12 ng/mL (P = 0.77). There was no significant variance between the healthy and epileptic neonates (P = 0.212).

Conclusion:
The current studyficant variance between the healthy and epileptic neonates (eptic with convulsions. Termserum vit D levels and epileptic activity in neonates. Nevertheless, the levels of the vitamin were < 20 ng/mL among all the neonates. Interventions to improve the vit D levels have to be implemented.
Auto-PAP Titration Efficacy in Obstructive Sleep Apnea: A Single-Center Experience
Authors: Gabhale Sanjay D. , Gupta Ekta , Bagrecha Mahavir Satishchand , Saifuddin Rehan , Nelson Anish , Sharma Mayank 
Published: February 2024

ABSTRACT

Introduction:

Obstructive sleep apnea, often known as OSA, is a sleep-related breathing disease that, if not treated, can lead to serious disabilities or even death. Continuous positive airway pressure (CPAP) is the therapy technique that is suggested for treating severe and moderate OSA. An auto/manual CPAP titration study can be used to determine the appropriate pressure that must be maintained to treat this condition. The motive of this research is to appraise the effectiveness among OSA patients for the auto-PAP titrations.

Methodology:
A cross-sectional clinical prospective study was conducted at the tertiary care center. Subjects who underwent auto-PAP titration and had a diagnosis of moderate and sever OSA were included. They were evaluated for the efficacy of auto-PAP titration and other demographic features and their association with the titration efficacy. The values were compared for statistical significance.

Results:
The findings of the study showed that fifty percent of the cohort showed optimal titration, forty percent showed good titration, ten percent showed suitable titration, and none fell into the unacceptable group.

Conclusion:
According to the findings, using auto-PAP was associated with positive results in those with moderate and severe OSA. There is evidence to suggest that unattended auto-PAP titration is a very successful technique that might be regarded as a substitute for attended CPAP titrations. This would result in a reduction in the amount of labor required and the price.
Clinical Evaluation of Coronally Advanced Flap with or without a Platelet-Rich Fibrin Membrane for the Root Coverage
Authors: Jaiswal Rajeev K. , Chandra Deepti , Khan Md Arif , Gupta Sanjay , Gowrav Piyush , Yadav Surendra Kumar 
Published: February 2024

ABSTRACT

Aim:
To evaluate “coronally advanced flap” with or without “a platelet-rich fibrin membrane for the root coverage.”

Materials and Methods:
All the clinical parameters were assessed at different time intervals (at baseline, 1, 3, and 6 months) in both experimental and control group. Following “clinical parameters” were recorded using “UNC-15” “Probe-Plaque Index (PI)” (Silness and Loe, 1964), “Gingival Index” (GI) (Loe and Silness, 1963), “Recession depth (RD),” “Recession width (RW),” “Clinical attachment level (CAL),” and “Width of keratinized gingiva (WKG)”.

Results:
At final evaluation (i.e., mean change from baseline to 6 months), “the decrease in Plaque Index was 2.5% higher in Group B (66.0%) as compared to Group A (63.5%). The decrease in Gingival Index was 6.1% higher in Group B (91.4%) as compared to Group A (85.3%), and the decrease in recession width was 4.0% higher in Group B (75.2%) as compared to Group A (71.2%). The decrease in clinical attachment level was 4.4% higher in Group B (53.2%) as compared to Group A (48.4%). The increase in width of keratinized gingiva was 1.9% higher in Group A (28.8%) as compared to Group B (26.9%).”

Conclusion:
The controlled, randomized, split mouth design showed that CAF surgery, either by alone or in combination with PRF, is an efficient treatment method for covering denuded roots. “This design was used to treat bilateral isolated Miller’s class I and II recessions in gingival part. When compared to the CAF approach, the results from a combination of CAF and PRF after a 6-month period showed additional advantages in addition to mean root coverage in the treatment of Miller’s classes I and II recessions in gingival part.”
Comparative Assessment of Herbal Mouthwash with Chlorhexidine on Plaque Accumulation, Gingivitis, and Salivary Streptococcus mutans Growth
Authors: Bindal Ruchi , Gulati Prerna , Sharma Shaivi , Kaur Manpreet , Varshney Anchal , Jain Parul , Patidar Madhvika 
Published: February 2024

ABSTRACT

Objectives:
The goal of the current study was to assess the effectiveness of a commercially available herbal mouthwash with chlorhexidine on the number of Streptococcus mutans in the saliva, the condition of the gingival tissue, and plaque development.

Materials and Methods:
Twenty-two adults in all, ranging in age from 20 to 30, were divided into two groups at random. Throughout the 14-day clinical trial, Group A (11) and Group B (11) received 10 mL of test herbal mouthwash and chlorhexidine, respectively.

Result:
Herbal mouthwash was discovered to be equally as effective as chlorhexidine in lowering the salivary mutans streptococci count and in affecting plaque and gingival scores.

Conclusion:
Alternatives from the herbal world may show to be a reliable and secure therapy option.
Comparative Study on Efficacy of Empagliflozin Versus Sitagliptin, as an Add-on Therapy to Metformin in Type 2 Diabetic Patients
Authors: Salankar Harsh , Rode Sonali , Arjun C. , Joseph Rajeeta , Deshmane Gourav B. , Vijayan Radhika P. 
Published: February 2024

ABSTRACT

Introduction:
More than 28.7 million individuals throughout the globe suffer from diabetes mellitus, with an estimated 11 percent of the population living with the condition in India. Changes in lifestyle and a variety of treatment plans are used in management. Metformin is a key drug for glycemic control, both when used alone and in combination. Our research compares the effectiveness of glycemic control achieved by empagliflozin plus sitagliptin.

Methods:
This study took place from November 2022 to April 2023 at the tertiary care hospital. The study did not begin until the ethical review was completed. There were two groups of patients, A and B. Everyone received a daily dose of Metformin 1,000 milligrams. Sitagliptin (50 mg twice daily) was administered to individuals in Group A, whereas Empagliflozin (10 mg once daily) was given to those in Group B. After three months of therapy, HbA1c was used to compare the two groups’ levels of glycemic control to those at the start of treatment. To do this, we employed a proforma. Version 25 of the Statistical Package for the Social Sciences (SPSS Inc., Chicago, USA) was used for the analysis.

Results:
The average age of the 300 patients that participated in the trial was 42.33. There were 57.67% men and 42.33% females. “The mean reduction in HbA1c from baseline in Group A was −0.65 ± 0.11% and in Group B was −1.34 ± 0.13% with statistically significant P-value (P-value = 0.000).”

Conclusion:
The combination of Empagliflozin and Metformin is superior to that of Sitagliptin and Metformin for the maintenance of glycemic control.
Correlation of AMH with Cardiometabolic Markers in Polycystic Ovarian Syndrome: Systematic Review and Meta-Analysis
Authors: Kamboj Saloni , Banerjee Spondita , Das Gita , Thakkar Smit , Atluri Rohith , Shivakumar Shruti , Tiwari Heena D. 
Published: February 2024

ABSTRACT

Objective:
The purpose of this systematic review and meta-analysis was to determine whether there is a connection between polycystic ovarian syndrome (PCOS)-affected women’s levels of the anti-Mullerian hormone (AMH) and certain cardiometabolic indicators.

Materials and Methods:
To find pertinent recent research published between 2017 and 2023, a thorough search was done in PubMed. Studies were included if they looked into the relationship between PCOS-related women’s AMH levels and cardiometabolic markers. To determine pooled effect estimates, data from the included studies were examined using random-effects models.

Results:
Five papers were included in the meta-analysis since they satisfied the inclusion requirements. The meta-analysis found substantial positive relationships between AMH levels and markers of insulin resistance, fasting blood sugar levels, and dyslipidemia measures such as total cholesterol (SMD: 0.68, 95% confidence interval: 0.34–1.00, P < 0.001).

Conclusion:
This systematic review and meta-analysis show that AMH levels in PCOS-affected women significantly positively correlate with markers of insulin resistance, fasting glucose levels, and dyslipidemia parameters. These findings imply that the pathogenesis of the cardiometabolic abnormalities seen in PCOS may include AMH. AMH may be used as a biomarker to estimate the cardiometabolic risk in PCOS-affected women, but more studies are required to determine its clinical applicability.
Outcomes of Regenerative Endodontic Treatment Performed Using Different Magnification Devices: A Systematic Review
Authors: Shaik Izaz , Veluru Keerthini , Sai Pranathi Gundimeda Naga , Jeevan Kakumanu Navya , Gowraram Sanjupriya , Pasupuleti Sowmya , Dikkala Naga Sri Samharsha 
Published: February 2024

ABSTRACT

Aim:
In this systematic review, we assessed whether the effects of the usage of various devices help with magnification in endodontics and whether they resulted in any significant changes in the clinical result of treatment.

Materials and Methods:
An exhaustive search was performed across MEDLINE and Cochrane Registers for various clinical studies, which were focused on comparing regenerative endodontic treatment based on the usage of magnification devices. Various terms were used to search these clinical trials such as microscope, regenerative endodontic surgery, apicoectomy, endoscope, and loupes.

Results:
After scrutinizing the studies, around three clinical trials based on magnification in endodontic surgeries were included in the present review. It was observed that no statistically noteworthy betterment of treatment outcome was seen in patients treated with either of the magnification devices such as loupes and microscope.

Conclusion:
It was evident that these magnification devices can alter the effectiveness of regenerative endodontic treatment in a very minimal way. However, we believe that more randomized clinical studies should be conducted in this area.
Salivary Interleukin-1 Levels in Oral Squamous Cell Carcinoma: A Case-Control Study
Authors: Vala Dushyantsinh , Shah Jill , Purba Arman K. , Mehta Tarang , Mansata Anuj V. , Almalki Sultan A. , Makkad Ramanpal S. 
Published: February 2024

ABSTRACT

Objective:
Oral squamous cell carcinoma (OSCC) is a prevalent malignancy with a significant impact on global health. The identification of non-invasive biomarkers for early detection and monitoring of OSCC remains crucial.

Methods:
A total of 100 subjects, comprising 50 patients with histopathologically confirmed OSCC and 50 age- and sex-matched healthy controls, were enrolled in the study. Salivary samples were collected from all participants and analyzed using enzyme-linked immunosorbent assays (ELISA) to measure IL-1 levels. Clinical data, including demographic information, smoking habits, and alcohol consumption, were obtained from patient records.

Results:
The mean salivary IL-1 level was significantly higher in OSCC patients compared to healthy controls (P < 0.001). Furthermore, subgroup analysis demonstrated that advanced stages of OSCC correlated with significantly elevated IL-1 levels when compared to early-stage OSCC (P < 0.05). Additionally, high salivary IL-1 levels were associated with a more aggressive tumor phenotype and poorer prognosis, as reflected by tumor size, lymph node metastasis, and overall survival (P < 0.01).

Conclusion:
This case-control study provides compelling evidence that salivary Interleukin-1 (IL-1) levels are significantly elevated in patients with OSCC.
Evaluation of Glenoid Fossa Position in Class II Malocclusion Associated with Mandibular Retrusion and Class III Malocclusion Associated with Mandibular Protrusion
Authors: Chandrika P. Sindhu , Alla Ramya , Duddu Yesuratnam , Adarsh Kumar , Varma Praveen K. , Mandava Prasad 
Published: February 2024

ABSTRACT

Objective:
This study examined the glenoid fossa in Class II and Class III malocclusions with mandibular retrusion and protrusion.

Materials and Methods:
A retrospective investigation examined 60 Class II and 60 Class III cephalometric radiographs. Cephalometric landmarks and glenoid fossa measurements were taken. Statistical analysis contrasted the two malocclusion groups’ glenoid fossas.

Results:
Class II malocclusion had a much lower mean Sella–Nasion–Condylion (SNCd) angle (glenoid fossa sagittal position) than Class III (14.6° ± 1.9). Class II malocclusion had a lower mean Sella–Nasion–Gonion (SNGo) angle (32.5° ± 4.3) than Class III (36.2° ± 3.9). The SNCd angle and SNGo angle in both groups demonstrated a negative correlation, demonstrating a relationship between the glenoid fossa and the mandibular sagittal axis.

Conclusion:
The glenoid fossa location differs significantly between Class II malocclusion with mandibular retrusion and Class III with protrusion. Class II malocclusion has a posterior glenoid fossa, while Class III has a less posterior one. Understanding these links may help patients receive more personalized treatment.