bluuebunny/crossref_metadata_2025_split huggingface dataset:
ChemInform Abstract: Overcoming hERG Issues for Brain‐Penetrating Cathepsin S Inhibitors: 2‐Cyanopyrimidines. Part 2.
Authors: Irie Osamu , et al. et al. 
Published: January 2009

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Reactions of 6‐Aminouracils — A Novel and Highly Efficient Procedure for Preparation of Some New Spiro Pyridodipyrimidines under Classical or Microwave‐Assisted Solvent‐Free Conditions.
Authors: Mohammadizadeh Mohammad R. , Azizian Javad , Teimouri Fatemeh , Mohammadi Ali A. , Karimi Ali R. , Tamari Esmail 
Published: January 2009

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis and Reactivity in [3 + 2] Cycloadditions of Isoxanthopterin N(5)‐Oxides — A New Synthesis of 6‐Substituted Pteridinediones.
Authors: Steinlin Thomas , Sonati Tiziana , Vasella Andrea 
Published: January 2009

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Palladium‐Catalyzed Disilylation of o‐Quinodimethanes: Synthesis of 9‐ and 10‐Membered Disilacarbocycles.
Authors: Yoshida Hiroto , Nakano Saori , Mukae Masashi , Ohshita Joji 
Published: January 2009

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Revisiting the Hirao Cross‐Coupling: Improved Synthesis of Aryl and Heteroaryl Phosphonates.
Authors: Belabassi Yamina , Alzghari Saeed , Montchamp Jean‐Luc 
Published: January 2009

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Asymmetric Total Synthesis of (+)‐Curcutetraol (Ia) and (+)‐Sydonol (Ib).
Authors: Ito Suguru , Zhang Chenxia , Hosoda Naoya , Asami Masatoshi 
Published: January 2009

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Kopreasin A, a New Indole Alkaloid from Kopsia arborea.
Authors: Zaima Kazumasa , Matsuno Yosuke , Hirasawa Yusuke , Rahman Abdul , Indrayanto Gunawan , Zaini Noor Cholies , Morita Hiroshi 
Published: January 2009

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: The Lyconadins: Enantioselective Total Syntheses of (+)‐Lyconadin A and (‐)‐Lyconadin B.
Authors: Beshore Douglas C. , Smith Amos B. III 
Published: January 2009

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: A Carbohydrate‐Linked Hypericinic Photosensitizing Agent.
Authors: Zuschrader Joachim , Schoefberger Wolfgang , Falk Heinz 
Published: January 2009

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Total Synthesis of Aburatubolactam A.
Authors: Henderson James A. , Phillips Andrew J. 
Published: January 2009

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis of Colloidal CuGaSe2, CuInSe2, and Cu(InGa)Se2 Nanoparticles.
Authors: Tang Jiang , Hinds Sean , Kelley Shana O. , Sargent Edward H. 
Published: January 2009

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Bridging the Gap Between Surface Science and Industrial Catalysis
Authors: Meunier Frederic C. 
Published: January 2009

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Engineered Weld Design: Are Composite Welds Likely in the Future?
Authors: Olson D. L. , Park Y. D. , Liu S. , Jackson J. E. , Lasseigne‐Jackson A. N. , Metzbower E. 
Published: January 2009

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Some Aspects of Colloidal Nanoparticle Stability, Catalytic Activity, and Recycling Potential
Authors: Narayanan Radha , El‐Sayed Mostafa A. 
Published: January 2009

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Manganese‐Containing Heterometallic Clusters with Ligands Derived from Elements of Groups 15 and 16
Authors: Mathur Pradeep , Chatterjee Saurav , Torubaev Yuri V. 
Published: January 2009

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Recent Progress in the Chemistry and Applications of Indolocarbazoles
Authors: Janosik Tomasz , Wahlstroem Niklas , Bergman Jan 
Published: January 2009

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Palladium‐Catalyzed Carbonylation — A Reaction Come of Age
Authors: Barnard Christopher F. J. 
Published: January 2009

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Electrophilic Bromination of Alkenes: Environmental, Health and Safety Aspects of New Alternative Methods.
Authors: Eissen Marco , Lenoir Dieter 
Published: January 2009

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Challenges in the Stereocontrolled Syntheses of β‐Rhamnosides.
Authors: El Ashry El Sayed H. , Rashed Nagwa , Ibrahim El Sayed I. 
Published: January 2009

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Zwitterionic Iodonium Compounds: Useful Tools in Organic Synthesis
Authors: Malamidou‐Xenikaki Elizabeth , Spyroudis Spyros 
Published: January 2009

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Catalysis by Very Small Au Clusters
Authors: Chretien Steeve , Buratto Steven K. , Metiu Horia 
Published: January 2009

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Recent Applications of Microwaves in Synthesis of Bioactive Heterocyclic Compounds
Authors: Jindal Rani , Bajaj Sanjay 
Published: January 2009

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Nitroalkanes as Central Reagents in the Synthesis of Spiroketals
Authors: Ballini Roberto , Petrini Marino , Rosini Goffredo 
Published: January 2009

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Highlights in Steroidal Chemistry: Total Synthesis versus Semisynthesis
Authors: Nising Carl F. , Braese Stefan 
Published: January 2009

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: The Azadirachtin Story
Authors: Veitch Gemma E. , Boyer Alistair , Ley Steven V. 
Published: January 2009

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Comprehensive Survey of Chemical Libraries for Drug Discovery and Chemical Biology: 2007.
Authors: Dolle Roland E. , Le Bourdonnec Bertrand , Goodman Allan J. , Morales Guillermo A. , Thomas Craig J. , Zhang Wei 
Published: January 2009

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Free Radical and Ionic Routes Toward Hydrolytically Stable and Bioactive C‐Glycosyl Compounds
Authors: Chen Guo‐Rong , Praly Jean‐Pierre 
Published: January 2009

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Bonding Properties and Bond Activation of Ylides: Recent Findings and Outlook
Authors: Urriolabeitia Esteban P. 
Published: January 2009

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Fluorous Biphasic Catalysis
Authors: Mathison Clare R. , Cole‐Hamilton David J. 
Published: January 2009

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Energy Upgrading by Solid‐Gas Reaction Heat Transformer: A Critical Review
Authors: Yu Y. Q. , Zhang P. , Wu J. Y. , Wang R. Z. 
Published: January 2009

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Guiding cell migration in 3D: A collagen matrix with graded directional stiffness
Authors: Hadjipanayi Ektoras , Mudera Vivek , Brown Robert A. 
Published: January 2009

AbstractWhile matrix stiffness has been implicated in cell adhesion and migration, most studies have focused on the effects of substrate stiffness in 2D. The present work describes a novel continuous stiffness gradient model for studying such processes in 3D. Wedge‐shaped collagen scaffolds were compressed to produce sheets of a desired (0.1 mm) uniform thickness, but with increasing collagen density along the length of the sheet. Dynamic mechanical analysis, carried out on 1 mm wide strips obtained from the two ends and the middle of each sheet, showed that the elastic modulus increased from 1057 ± 487 kPa to 2305 ± 693 kPa at the soft and stiff end respectively and was 1835 ± 31 kPa in the middle. In constructs seeded with agarose marker beads prior to compression, mean agarose bead density rose from 10 ± 1 to 71 ± 12 at the soft and stiff end respectively and was 19 ± 5 in the middle, indicating successful engineering of a density gradient corresponding to the measured stiffness gradient. Growth‐arrested human dermal fibroblasts, initially seeded evenly within such constructs, accumulated preferentially towards the stiff part of the gradient after 3 and 6 days in culture. Durotactic migration was significant after 6 days. This model provides a new means for studying cellular mechanotaxis and patterning cells which is controllable, biomimetic and in 3D. Cell Motil. Cytoskeleton 66: 121–128, 2009. © 2009 Wiley‐Liss, Inc.
Nonglycosidic Agonists of Invariant NKT Cells for Use as Vaccine Adjuvants
Authors: Reddy B. Gopal , Silk Jonathan D. , Salio Mariolina , Balamurugan Rengarajan , Shepherd Dawn , Ritter Gerd , Cerundolo Vincenzo , Schmidt Richard R. 
Published: January 2009

AbstractBased on the crystal structures of human α‐GalCer–CD1d and iNKT–α‐GalCer–CD1d complexes, nonglycosidic analogues of α‐GalCer were synthesized. They activate iNKT cells resulting in dendritic cell maturation and the priming of antigen‐specific T and B cells. Therefore, they are attractive adjuvants in vaccination strategies for cancer and infectious diseases.magnified image
Health‐related quality of life in long‐term breast cancer survivors
Authors: Paskett Electra , Herndon James , Donohue Kathleen , Naughton Michelle , Grubbs Stephen , Pavy Michael , Hensley Martee , Stark Nancy , Kornblith Alice , Bittoni Marisa 
Published: January 2009

AbstractBACKGROUND:The Survivor's Health and Reaction (SHARE) study examined health‐related quality of life (HRQL) in breast cancer patients who had participated in Cancer and Leukemia Group B Trial 8541 from 1985 to 1991.METHODS:In total, 245 survivors (78% of eligible patients) who were 9.4 to 16.5 years postdiagnosis (mean, 12.5 years postdiagnosis) completed HRQL surveys relating to 5 domains. Analyses examined HRQL domains according to 3 different chemotherapy dose levels that were administered in the original treatment trial: low‐dose cyclophosphamide, doxorubicin, and fluorouracil (CAF) at 300 mg/m2, 30 mg/m2, and 300×2 mg/m2, respectively, over 4 cycles; standard‐dose CAF at 400 mg/m2, 40 mg/m2, and 400×2 mg/m2, respectively, over 6 cycles; and high‐dose CAF at 600 mg/m2, 60 mg/m2 and 600×2 mg/m2, respectively, over 4 cycles.RESULTS:In univariate analyses, a statistically significant difference was observed on the Medical Outcomes Study 36‐item short form Physical Role Functioning subscale by treatment group, with lower mean scores in the standard treatment arm (mean, 65.05) compared with mean scores in the low‐dose arm (mean, 74.66) and the high‐dose arm (mean, 84.94; P.0001). However, multivariate analysis revealed that treatment arm no longer was statistically significant, whereas the following factors were associated with decreased physical role functioning: age ≥60 years (odds ratio [OR], 3.55; P = .006), increased comorbidity interference total score (OR, 1.64; P = .005), lower vitality (OR, 1.05; P = .0002), and increased menopausal symptoms (OR, 1.04 P = .02).CONCLUSIONS:At 9.4‐16.5 years after their original diagnosis, differences in physical role functioning among breast cancer survivors who had received 3 different dose levels of chemotherapy were explained by clinical and demographic variables, such as age, fatigue, menopausal symptoms, and comorbidities. Prospective studies are needed to further assess the role of these factors in explaining HRQL and physical role functioning among long‐term survivors. Cancer 2009. © 2009 American Cancer Society.
Noninvasive evaluation of oral lesions using depth‐sensitive optical spectroscopy
Authors: Schwarz Richard A. , Gao Wen , Redden Weber Crystal , Kurachi Cristina , Lee J. Jack , El‐Naggar Adel K. , Richards‐Kortum Rebecca , Gillenwater Ann M. 
Published: January 2009

AbstractBACKGROUND:Optical spectroscopy is a noninvasive technique with potential applications for diagnosis of oral dysplasia and early cancer. In this study, we evaluated the diagnostic performance of a depth‐sensitive optical spectroscopy (DSOS) system for distinguishing dysplasia and carcinoma from non‐neoplastic oral mucosa.METHODS:Patients with oral lesions and volunteers without any oral abnormalities were recruited to participate. Autofluorescence and diffuse reflectance spectra of selected oral sites were measured using the DSOS system. A total of 424 oral sites in 124 subjects were measured and analyzed, including 154 sites in 60 patients with oral lesions and 270 sites in 64 normal volunteers. Measured optical spectra were used to develop computer‐based algorithms to identify the presence of dysplasia or cancer. Sensitivity and specificity were calculated using a gold standard of histopathology for patient sites and clinical impression for normal volunteer sites.RESULTS:Differences in oral spectra were observed in: (1) neoplastic versus nonneoplastic sites, (2) keratinized versus nonkeratinized tissue, and (3) shallow versus deep depths within oral tissue. Algorithms based on spectra from 310 nonkeratinized anatomic sites (buccal, tongue, floor of mouth, and lip) yielded an area under the receiver operating characteristic curve of 0.96 in the training set and 0.93 in the validation set.CONCLUSIONS:The ability to selectively target epithelial and shallow stromal depth regions appeared to be diagnostically useful. For nonkeratinized oral sites, the sensitivity and specificity of this objective diagnostic technique were comparable to that of clinical diagnosis by expert observers. Thus, DSOS has potential to augment oral cancer screening efforts in community settings. Cancer 2009. © 2009 American Cancer Society.