bluuebunny/crossref_metadata_2025_split huggingface dataset:
A New Method Used to Enhance the SPAIR Image of the Spine MRI
Authors: Fan Huayu , Cao Xiangyang , Wu Mingxiang , Zhao Mingyu , Liu Liyun , Song Yongwei , Zhang Xiangdong , Zhang Binqing 
Published: February 2024

Background::
Magnetic resonance imaging (MRI) is a handy diagnostic tool for orthopedic disorders, particularly spinal and joint diseases.

Methods::
The lumbar intervertebral disc is visible in the T1 and T2 weight sequences of the spine MRI, which aids in diagnosing lumbar disc herniation,
lumbar spine tuberculosis, lumbar spine tumors, and other conditions. The lumbar intervertebral disc cannot be seen accurately in the Spectral
Attenuated Inversion Recovery (SPAIR) due to weaknesses in the fat and frequency offset parameters, which is not conducive to developing the
intelligence diagnosis model of medical image.

Results::
In order to solve this problem, we propose a composite framework, which is first to use the contrast limited adaptive histogram equalization
(CLAHE) method to enhance the SPAIR image contrast of the spine MRI and then use the non-local means method to remove the noise of the
image to ensure that the image contrast is uniform without losing details. We employ the Information Entropy (IE), Peak signal-to-noise ratio
(PSNR), and feature similarity index measure (FSIM) to quantify image quality after enhancement by the composite framework.

Conclusion::
The outcomes of the experiments’ output images and quantitative data indicate that our composite framework is better than others.
Prediction of Microwave Ablation Recurrence in Pulmonary Malignancies
Using Preoperative Computed Tomography Radiomics Models
Authors: Zhu Fandong , Yang Chen , Yang Jing , Mao Haijia , Huang Yanan , Liu Hao , Zhao Zhenhua 
Published: February 2024

Background::
The aim of this study was to develop and evaluate preoperative computed tomography (CT) radiomics models as noninvasive diagnostic methods for predicting MWA recurrence in pulmonary malignancies.Assessing the early efficacy of microwave ablation (MWA) for pulmonary malignancies is a challenge for interventionalists. However, performing
an accurate efficacy assessment at an earlier stage can significantly enhance clinical intervention and improve the patient’s prognosis.

Purpose::
This research aimed to create and assess non-invasive diagnostic techniques using pre-operative computed tomography (CT) radiomics models to
predict the recurrence of MWA in pulmonary malignancies.

Materials and Methods::
We retrospectively enrolled 116 eligible patients with pulmonary malignancies treated with MWA. we separated the patients into two groups: a
recurrence group (n = 28) and a non-recurrence group (n = 88), following the modified Response Evaluation Criteria in Solid Tumors (m-RECIST)
criteria. We segmented the preoperative tumor area manually. We expanded outward the tumor boundary 4 times, with a width of 3 mm, using the
tumor boundary as the baseline. Five groups of radiomics features were extracted and screened using max-relevance and min-redundancy (mRMR)
and least absolute shrinkage and selection operator (LASSO) regression. Weight coefficients of the aforementioned features were used to calculate
the Radscore and construct radiomics models for both tumoral and peritumoral areas. The Radscore from the radiomics model was combined with
clinical risk factors to construct a combined model. The performance and clinical usefulness of the combined models were assessed through the
evaluation of receiver operating characteristic (ROC) curves, the Delong test, calibration curves, and decision curve analysis (DCA) curves.

Results::
The clinical risk factor for recurrence after MWA was tumor diameter (P < 0.05). Both tumoral and four peritumoral radiomics models exhibited
high diagnostic efficacy. Furthermore, the combined 1 (C1)-RO model and the combined 2 (C2)-RO model showed higher efficacy with area under
the curve (AUCs) of 0.89 and 0.89 in the training cohort, and 0.93 and 0.94 in the validation cohort, respectively. Both combined models
demonstrated excellent predictive accuracy and clinical benefit.

Conclusion::
Preoperative CT radiomics models for both tumoral and peritumoral regions are capable of accurately predicting the recurrence of pulmonary
malignancies after MWA. The combination of both models may lead to better performance and may aid in devising more effective preoperative
treatment strategies.
A Good Prognosis of Patients with Acute Pancreatitis Combined with
Pulmonary Embolism: Early Identification and Intervention
Authors: Yan Ling-ling , Li Shao-wei , Fang Yu-xin , Yan Xiao-dan , He Bi-li 
Published: February 2024

Background::
Pulmonary embolism (PE) is a relatively rare vascular complication of acute pancreatitis (AP), and its mortality rate is high. To our knowledge,
relevant literature reports still need to be summarized. In this study, we analyzed the clinical characteristics, treatment, and prognosis of five
patients with AP complicated by PE and summarized and reviewed the relevant literature.

Methods::
Clinical data of patients with AP complicated by PE treated in Taizhou Hospital of Zhejiang Province between January 2017 and September 2022
were retrospectively collected. Combined with the relevant literature, the clinical characteristics, treatment, and prognoses of patients with AP
combined with PE were analyzed and summarized.

Results::
Five patients were eventually enrolled in this study. Among the five patients with AP complicated by PE, all (100%) had symptoms of malaise,
primarily chest tightness, shortness of breath, and dyspnea. All patients (100%) had varied degrees of elevated D-dimer levels and a significant
decrease in the pressure of partial oxygen (PO2) and pressure of arterial oxygen to fractional inspired oxygen concentration ratio (PaO2/FiO2).
Computed tomographic angiography (CTA) or pulmonary ventilation/perfusion imaging revealed a pulmonary artery filling defect in these
patients. One patient (20%) had left calf muscular venous thrombosis before the occurrence of PE. Four patients (80%) were treated with lowmolecular-
weight heparin (LMWH), and one patient (20%) was treated with rivaroxaban during hospitalization; all continued oral anticoagulant
therapy after discharge. All patients (100%) were cured and discharged. No patients showed recurrence of AP or PE.

Conclusion::
PE is a rare but life-threatening complication of AP. However, once diagnosed, early treatment with anticoagulation or radiological interventional
procedures is effective, and the prognosis is good.

Core Tips::
Pulmonary embolism (PE) is a rare but life-threatening complication of acute pancreatitis (AP). Its early diagnosis and timely anticoagulation or
radiological intervention can reduce mortality. However, only nine cases have been reported in the English literature thus far, and they are all case
reports. Our study is the first systematic analysis of patients with AP combined with PE with a review of the relevant literature. Our patients and
those reported in the literature were discharged with good prognoses under treatment such as anticoagulation and vascular intervention. These
cases remind clinicians that, in patients with AP, especially those with risk factors for venous thrombosis, it is necessary to monitor the D-dimer
level dynamically. Clinicians should pay attention to AP patients' symptoms and related examinations to reduce the chance of a missed diagnosis
or misdiagnosis of PE.
Analisis keterampilan komunikasi pada pembelajaran biologi sekolah menengah atas
Authors: Urwani Assabai Nizar , Ramli Murni , Ariyanto Joko 
Published: February 2024

Penelitian bertujuan untuk mengetahui dominasi komunikasi scientific pada pembelajaran biologi di kelas X IPA 1, mengetahui dominasi komunikasi scientific pada pembelajaran biologi di kelas XI IPA 1, dan mengetahui hambatan keterampilan komunikasi siswa pada pembelajaran biologi. Penelitian yang dilakukan merupakan penelitian observasi kelas (classroom observation). Observasi dilakukan di dua kelas, yaitu kelas X IPA 1 dan kelas XI IPA 1. Observasi dilakukan selama 5 kali observasi pada masing-masing kelas. Observasi dilakukan dari tanggal 22 Februari 2017 sampai 10 Mei 2017. Observasi dilakukan dengan cara mencatat seluruh komunikasi antara siswa dan guru selama proses pembelajaran biologi. Subjek penelitian adalah siswa kelas X IPA 1 dan XI IPA 1 MAN 2 Surakarta tahun ajaran 2016/2017 pada semester genap. Teknik pengambilan subjek penelitian dilakukan dengan cara purposive sampling berdasarkan pertimbangan dari guru. Teknik pengumpulan data dilakukan dengan cara observasi, wawancara, dan dokumentasi. Analisis data menggunakan matriks kategori VICS Flanders. Hasil penelitian menunjukkan dominasi komunikasi scientific selama observasi di kelas X IPA 1 dan XI IPA 1 adalah dominasi komunikasi yang seimbang atau komunikasi dua arah. Persentase dominasi komunikasi yang seimbang di kelas X IPA 1 adalah 50,26%, sedangkan persentase dominasi komunikasi yang seimbang di kelas XI IPA 1 adalah 43,08%. Hambatan komunikasi scientific siswa, yaitu hambatan psikologis, fisik, semantik, dan proses.Analysis of communications skill on biology learning high school AbstractThe research aims to find out the dominance of scientific communication in biology learning of class X IPA 1, to find out the dominance of scientific communication in biology learning of class XI IPA 1, and to find out the communication barriers occurred in the biology learning. The research was a classroom observation research. The observations were conducted in two class (class X IPA 1 and class XI IPA 1). The observations of each class were made five times. The observations were conducted from the 22 February 2017 to 10 May 2017. The observation recorded all communication between students and teacher during the process learning biology. The population of this research was students of class X IPA 1 and XI IPA 1 in MAN 2 Surakarta. The subjects were selected using purposive sampling recommended by the biology teacher. The data were collected by the observations, interviews, and documentations. The data were analyzed using the VICS Flanders matrix. The results showed the dominance of scientific communications in class X IPA 1 and XI IPA 1 of MAN 2 Surakarta was balanced or two-way communication. The percentage of the dominance of scientific communications in class X IPA 1 was 50.26 %. The percentage of the dominance of scientific communications in class XI IPA 1 was 43.08%. The barriers to the students' communications were psychological, physical, semantic, and process.
Elclivs berbasis inquiry untuk meningkatkan penguasaan konsep siswa tuna netra pada materi rangkaian listrik
Authors: Widiyawati Yeni , Nurwahidah Indri 
Published: February 2024

Tujuan penelitian ini yaitu untuk mengetahui efektivitas Elclivs berbasis Inquiry untuk meningkatkan penguasaan konsep siswa tunanetra pada materi rangkaian listrik. Metode yang digunakan dalam penelitian ini yaitu quasi experiment dengan desain one-group prettest-posttest. Partisipan yang digunakan yaitu siswa tunanetra kelas IX di SLB A Dria Adi dan SLB A YAAT. Berdasarkan hasil uji gain standar, 3 dari 5 siswa yang mengikuti pretes dan postes menunjukkan peningkatan penguasaan konsep yang baik. Hasil uji Wilcoxon menunjukkan bahwa penerapan Elclivs berbasis Inquiry belum signifikan untuk meningkatkan penguasaan konsep siswa. Perhitungan bilangan pecahan merupakan kelemahan utama siswa tunanetra dalam menguasai konsep rangkaian listrik. Namun, hasil observasi menunjukkan bahwa minat belajar, antusiame dan penalaran siswa saat mengikuti pembelajaran meningkat melalui penerapan Elclivs berbasis Inquiry. Keterampilan berhitung dalam hal ini hanya alat bantu untuk menguasai konsep. Dengan demikian hasil penelitian yang diperoleh dapat disimpulkan bahwa Elclivs dapat menigkatkan penguasaan konsep siswa pada materi rangkaian listrik. Elclivs-inquiry based to enhance visual impairment student conceptual understanding in electricity circuit topics AbstractThe aims of this research to know the effectiveness of Elclivs-Inquiry-based to enhance conceptual understanding on Electricity circuit topics of visual impairment student. One-group pretest-posttest quasi-experimental design was used. IX grade visual impairment students in Dria Adi and YAAT Klaten Special Education School have participated in this research. 3 of 5 students who take the pretest and posttest obtained the good level of conceptual understanding normalized gain. Wilcoxon test was showed that Elclivs-Inquiry-based implementation is not significant to enhance visual impairment student conceptual understanding. Fraction number calculations is the most visual impairment lacks to understanding the electricity circuit concept. However, the observation showed that the learning interest, enthusiasm, and reasoning of student increase by Elclivs-Inquiry-based implementation. Mathematics calculation skill is the tools to obtain the conceptual understanding. So it can conclude that Elclivs can enhance conceptual understanding of visual impairments students in electricity circuit topics.
The Development of Interactive Learning Media Based on Visual Basic for 8th Grade Junior High School in Application (VBA) on Additive, Addictive and Psychotropic Substances
Authors: Wati Erlina , Afiqah Nurul , Sari Anggi Kusuma , Rahmayumita Restesa , Nasir Muhammad 
Published: February 2024

This study aims to develop interactive learning media. The research method used is the ADDIE development research method. There are five stages of developing this interactive media, namely analysis, design, development, implementation, and evaluation. The assessment instrument consists of three experts and users. The data analysis technique used is the descriptive data analysis technique. The data that has been analyzed is then described qualitatively to find out the research category in each aspect, the design aspect with an average score of 0.819 with the high category, the pedagogic aspect 0.817 with the high category, the content aspect 0.817 with the high category, then for the last aspect the technique 0.07 moderate category. The developed simulation can be used, interactive, and can explain the concept well. Keywords: Addictive Substances, Learning Media, Interactive, Powerpoint VBA.
Effectiveness of eHealth Interventions Promoting Physical Activity in Children and Adolescents: Systematic Review and Meta-Analysis
Authors: Sequí-Domínguez Irene , Cavero-Redondo Iván , Álvarez-Bueno Celia , López-Gil Jose Francisco , Martínez-Vizcaíno Vicente , Pascual-Morena Carlos 
Published: February 2024

Background
eHealth interventions have been postulated as a feasible, acceptable, and possibly effective tool to promote physical activity (PA) among children and adolescents; however, a comprehensive quantitative analysis of the effects of eHealth interventions promoting PA is lacking.

Objective
This study aims to conduct a systematic review and meta-analysis on experimental studies reporting the effects of eHealth interventions aimed at promoting PA on PA parameters and sedentary behavior parameters in children and adolescents.

Methods
The CENTRAL, MEDLINE, Embase, and Web of Science databases were searched from inception to February 2022 for randomized controlled trials that analyzed the effects of eHealth interventions aimed at promoting PA on PA and sedentary parameters in children and adolescents. The Hartung-Knapp-Sidik-Jonkman random effects method was used to determine the mean differences (MDs) with their respective 95% CIs. The risk of bias was assessed using the Risk of Bias 2 (RoB2; Cochrane) tool and its extension for cluster randomized controlled trials. The certainty of evidence was evaluated using the Grading of Recommendations, Assessment, Development, and Evaluation (GRADE) tool.

Results
A total of 20 trials reporting the effects of different eHealth interventions aimed at promoting PA were included. Results for each parameter were as follows: counts per minute (MD −16.11 counts, 95% CI −122.76 to 90.53; k=3; n=402; I2=69%; favoring control), steps per day (MD 593.46 steps, 95% CI −2102.27 to 3289.19; k=2; n=152; I2=0%; favoring intervention [FI]), moderate to vigorous PA (MD −1.99 min/d, 95% CI −8.95 to 4.96; k=14; n=2336; I2=86%; favoring control), light PA (MD 3.28 min/d, 95% CI −15.48 to 22.04; k=5; n=355; I2=67%; FI), screen time (MD −31.48 min/d, 95% CI −68.62 to 5.65; k=5; n=904; I2=0%; FI), and sedentary time (MD −33.12 min/d, 95% CI −57.27 to −8.97; k=8; n=819; I2=75%; FI). Our results should be interpreted cautiously because of important limitations such as the scarcity of evidence, overall risk of bias, and low to very low certainty of evidence.

Conclusions
We did not find conclusive evidence regarding the impact of PA-targeted eHealth interventions on PA parameters, but the very low certainty of evidence suggests that eHealth interventions may reduce sedentary time in children and adolescents. Our results may have important scientific implications as they highlight that the rapid development of eHealth interventions to promote PA lacks robust supporting evidence.

Trial Registration
PROSPERO CRD42020211020; https://www.crd.york.ac.uk/prospero/display_record.php?RecordID=211020
N-of-1 Trials of Antimicrobial Stewardship Interventions to Optimize Antibiotic Prescribing for Upper Respiratory Tract Infection in Emergency Departments: Protocol for a Quasi-Experimental Study
Authors: Attal Hersh , Huang Zhilian , Kuan Win Sen , Weng Yanyi , Tan Hann Yee , Seow Eillyne , Peng Li Lee , Lim Hoon Chin , Chow Angela 
Published: February 2024

Background
Antimicrobial stewardship programs attempting to optimize antibiotic therapy and clinical outcomes mainly focus on inpatient and outpatient settings. The lack of antimicrobial stewardship program studies in the emergency department (ED) represents a gap in tackling the problem of antimicrobial resistance as EDs treat a substantial number of upper respiratory tract infection cases throughout the year.

Objective
We intend to implement two evidence-based interventions: (1) patient education and (2) providing physician feedback on their prescribing rates. We will incorporate evidence from a literature review and contextualizing the interventions based on findings from a local qualitative study.

Methods
Our study uses a quasi-experimental design to evaluate the effects of interventions over time in the EDs of 4 public hospitals in Singapore. We will include an initial control period of 18 months. In the next 6 months, we will randomize 2 EDs to receive 1 intervention (ie, patient education) and the other 2 EDs to receive the alternative intervention (ie, physician feedback). All EDs will receive the second intervention in the subsequent 6 months on top of the ongoing intervention. Data will be collected for another 6 months to assess the persistence of the intervention effects. The information leaflets will be handed to patients at the EDs before they consult with the physician, while feedback to individual physicians by senior doctors is in the form of electronic text messages. The feedback will contain the physicians’ antibiotic prescribing rate compared with the departments’ overall antibiotic prescribing rate and a bite-size message on good antibiotic prescribing practices.

Results
We will analyze the data using segmented regression with difference-in-difference estimation to account for concurrent cluster comparisons.

Conclusions
Our proposed study assesses the effectiveness of evidence-based, context-specific interventions to optimize antibiotic prescribing in EDs. These interventions are aligned with Singapore’s national effort to tackle antimicrobial resistance and can be scaled up if successful.

Trial Registration
ClinicalTrials.gov NCT05451863; https://clinicaltrials.gov/study/NCT05451836

International Registered Report Identifier (IRRID)
DERR1-10.2196/50417
Promoting student’s habits of mind and cognitive learning outcomes in science education
Authors: Ariyati Eka , Susilo Herawati , Suwono Hadi , Rohman Fatchur 
Published: February 2024

: Learning must be able to develop knowledge, skills, and mindsets so that the graduates produced have attitudes, abilities and knowledge that are integrated and skilled in life. One way to achieve learning can be done through habits of mind because the success of learning is strongly influenced by habits of mind. The purpose of this study is to as certain how habits of mind and cognitive learning outcomes in biology are affected by learning process oriented guided inquiry learning with blended learning support. A pretest-postest design wih a non-equivalent control group was employed in this study. The trial ran from February to June 2022. Utilizing the habits of mind questionnaire, pupils’ thought patterns were assessed. Essay tests are also used to evaluate the results of cognitive learning. In this study, google form, LMS, and google meet were used for data collection. Statistical Product and Service Solutions software version 23 is used for data analysis and the results of covariance analysis (ANCOVA) showed a p value < 0,005, meaning that POGIL-supported blended learning can empower habits of mind and cognitive learning outcomes in biology learning. There is a substantial difference between the outcomes of the least significant difference and increasing habits of mind and cognitive learning outcomes. As a result, POGIL with moodle support can be used to enhance students’ habits of mind and cognitive learning results in biology classes.
Industry 4.0: The role of small and medium-sized entreprises in Germany
Authors: Amorim Vanessa , Bernardes Óscar , Santos Bárbara , Rua Orlando 
Published: February 2024

Purposes: In the present study, the concepts inherent to Industry 4.0 and Mittelstand will be initially defined in a clear way, for a better understanding of the context under analysis. Afterwards, the current situation of Industry 4.0 in the German SME sector will be evaluated, presenting as results the respective inherent challenges and opportunities. In this follow-up, the research will conclude whether the concept of Industry 4.0 can represent a key success factor for the SME sector in Germany.
Methodology: The data analysis in the present research are based on a bibliographic review and an analysis of statistical data, seeking to represent a combination of quantitative and qualitative approaches.
Results: The challenges analyzed and discussed may be a possible justification for a slow reversal of traditional production processes for Industry 4.0. However, the numerous opportunities and their high implementation potential are preponderant for the adoption of the 4.0 industry in the production processes of the future.
Conclusions: This research shows that currently, there is still a high percentage of companies in the German SME sector that have not implemented Industry 4.0. However, the opportunities presented throughout the study, overcome the possible challenges posed in this context, as Industry 4.0 can considerably increase the profitability and efficiency of production as well as the overall competitiveness of the organization.
Keywords: digitization; industry 4.0; mittelstand; SME.