bluuebunny/crossref_metadata_2025_split huggingface dataset:
Numerical investigation of water entry of hydrophobic spheres
Authors: Singh Jaspreet , Pal Anikesh 
Published: April 2024

Abstract
We perform numerical simulations to study the dynamics of the entry of hydrophobic spheres in a pool of water. To track the air-water interface during the translation of the sphere in the pool of water, we use the volume of fluid model. The continuum surface force method computes the surface tension force. To represent the hydrophobic surface properties, we use wall adhesion in terms of a static contact angle. We perform simulations with different diameters and impact speeds of the sphere. Our simulations capture the formation of different types of air cavities, pinch-offs of these cavities, and other finer details similar to the experiments performed at the same parameters. Finally, we compare the drag force among the different hydrophobic cases. We further perform simulations of hydrophilic spheres impacting the pool of water and compare the drag force with the analogous hydrophobic cases. We conclude that the spheres with hydrophobic surfaces encounter a lower drag than their hydrophilic counterparts. This lower drag of the hydrophobic spheres is attributed to the formation of the air cavity by the hydrophobic surfaces while translating through the pool of water, which reduces the area of the sphere in contact with water. In contrast, no such air cavity forms in the case of hydrophilic spheres.
COVID-19-associated cerebral microbleeds in the general population
Authors: Sagar Malini V , Ferrer Neus R , Mehdipour Ghazi Mostafa , Klein Kiril V , Jimenez-Solem Espen , Nielsen Mads , Kruuse Christina 
Published: April 2024

Abstract
Cerebral microbleeds are frequent incidental findings on brain MRI and have previously been shown to occur in Coronavirus Disease 2019 (COVID-19) cohorts of critically ill patients. We aimed to determine the risk of having microbleeds on medically indicated brain MRI and compare non-hospitalized COVID-19-infected patients with non-infected controls. In this retrospective case-control study, we included patients over 18 years of age, having an MRI with a susceptibility-weighted sequence, between 1 January 2019 and 1 July 2021. Cases were identified based on a positive reverse transcriptase polymerase chain reaction test for SARS-CoV-2 and matched with three non-exposed controls, based on age, sex, body mass index and comorbidities. The number of cerebral microbleeds on each scan was determined using artificial intelligence. We included 73 cases and 219 matched non-exposed controls. COVID-19 was associated with significantly greater odds of having cerebral microbleeds on MRI [odds ratio 2.66 (1.23–5.76, 95% confidence interval)], increasingly so when patients with dementia and hospitalized patients were excluded. Our findings indicate that cerebral microbleeds may be associated with COVID-19 infections. This finding may add to the pathophysiological considerations of cerebral microbleeds and help explain cases of incidental cerebral microbleeds in patients with previous COVID-19.
A multiphase, multicentre development and validation of two maturity tools assessing the implementation of the FlaQuM co-creation roadmap
Authors: Claessens Fien , Van der Auwera Charlotte , Seys Deborah , De Ridder Dirk , Van Wilder Astrid , Vanhaecht Kris , Research Group and the FlaQuM 
Published: April 2024

Abstract
As part of the new Flanders Quality Model (FlaQuM) towards sustainable quality management systems, a co-creation roadmap with 6 primary drivers and 19 building blocks that guides healthcare organizations has been developed. Currently, no assessment tool is available to monitor hospitals’ quality management systems implementation according to this co-creation roadmap. Therefore, we aimed to measure the maturity of the implementation of the FlaQuM co-creation roadmap in hospitals. A three-phase approach in co-design with 19 hospitals started with defining the scope, followed by establishing content validity through a literature review, involvement of content experts (n = 47), 20 focus groups with content experts (n = 79), and a Delphi round with healthcare quality managers (n = 19) to test the content validity index. Construct validity was assessed by confirmatory factor analyses and convergent validity by Spearman’s ρ correlation coefficients. Based on 17 included existing maturity instruments and subcomponents of content experts, two maturity tools were developed according to the implementation of the FlaQuM co-creation roadmap: (i) a maturity matrix with 52 subcomponents and (ii) a co-creation scan with 19 statements. The overall scale-content validity index varied between 93.3% and 90.0% in terms of relevance and clarity, respectively. In a sample of 119 healthcare professionals, factor analyses revealed a six-factor structure and 16 (84.2%) of the 19 hypothesis for testing convergent validity between both maturity tools were statistically significant. Measuring the implementation of the FlaQuM co-creation roadmap and monitoring its maturity over time should be feasible by using these comprehensive maturity tools in hospitals. Results of both tools should be able to describe the current state of hospitals’ implementation of the co-creation roadmap as basis for strategic improvement plans and next steps.
Osteoblastic erythropoietin is not required for bone mass accrual
Authors: Lanzolla Giulia , Merceron Christophe , Khan Mohd Parvez , Sabini Elena , Giaccia Amato , Schipani Ernestina 
Published: April 2024

Abstract
Erythropoietin (EPO), primarily produced by interstitial fibroblasts in the kidney during adulthood, and its receptor are well-known for their crucial role in regulating erythropoiesis. Recent research has unveiled an additional function of circulating EPO in the control of bone mass accrual and homeostasis through its receptor, which is expressed in both osteoblasts and osteoclasts. Notably, cells of the osteoblast lineage can produce and secrete functional EPO upon activation of the hypoxia signaling pathway. However, the physiological relevance of osteoblastic EPO remains to be fully elucidated. This study aimed to investigate the potential role of osteoblastic EPO in regulating bone mass accrual and erythropoiesis in young adult mice. To accomplish this, we employed a mutant mouse model lacking EPO specifically in mesenchymal progenitors and their descendants. Our findings indicate that in vivo loss of EPO in the osteoblast lineage does not significantly affect either bone mass accrual or erythropoiesis in young adult mice. Further investigations are necessary to comprehensively understand the potential contribution of EPO produced and secreted by osteoblast cells during aging, repair, and under pathological conditions.
Risk of Invasive Meningococcal Disease in Preterm Infants
Authors: Calvert Anna , Campbell Helen , Heath Paul T , Jones Christine E , Le Doare Kirsty , Mensah Anna , Ladhani Shamez 
Published: April 2024

Abstract

Background
Invasive meningococcal disease (IMD) is most common in the first year of life. We hypothesized that preterm infants may have a higher risk of IMD and more severe disease than term infants. We compared the incidence, demographics, clinical presentation, and outcomes of IMD in preterm compared with term infants during the first 5 years after implementation of a national meningococcal group B vaccine (4CMenB) for infants in England.

Methods
The UK Health Security Agency conducts enhanced national IMD surveillance with detailed follow-up of all confirmed cases in England. Infants aged &lt;1 year (uncorrected for gestational age) with IMD confirmed between 1 September 2015 and 31 August 2020 were included.

Results
There were 393 infant IMD cases (incidence, 12.4/100 000 live births). Among 363 (92.4%) of the infants with known gestational age, the IMD incidence was higher in preterm (&lt;37 weeks’ gestation) than in term infants (18.3/100 000 vs 10.9/100 000; incidence rate ratio [IRR], 1.68 [95% confidence interval, 1.23–2.29]; P = .001). The IMD incidence was highest in those born at &lt;32 weeks’ gestation (32.9/100 000; incidence rate ratio for &lt;32 weeks’ gestation vs term, 3.01 [95% confidence interval, 1.73–5.24]; P ≤ .001). There were no differences in demographics, clinical presentation, rate of intensive care admission, or case-fatality rate, but preterm infants were more likely than term infants to have ≥1 reported sequela (14 of 39 [35.9%] vs 51 of 268 [19.0%]; P = .02).

Conclusions
Preterm infants had a higher incidence of IMD than term infants and the IMD incidence was highest in infants born at &lt;32 weeks’ gestation. Preterm infants also had a higher risk of IMD sequelae.
COVID-19 outbreak impact on urolithiasis treatments: A multicenter retrospective study across 9 urological centers in Italy
Authors: Mazzon Giorgio , Ferretti Stefania , Serafin Emanuele , Claps Francesco , Acquati Pietro , Brusa Davide , Germinale Federico , Celentano Giuseppe , Pescuma Andrea , Fugini Andrea Vismara , Campobasso Davide , Maestroni Umberto , Costa Giovanni , Morena Tonino , Di Marco Flavia , Baudo Andrea , Creta Massimiliano , Pavan Nicola , Ticonosco Marco , Peroni Angelo , Collura Devis , Cerruto Maria Angela , Antonelli Alessandro , Carmignani Luca , Micali Salvatore , Trombetta Carlo , Muto Giovanni , Celia Antonio 
Published: April 2024

Abstract

Background
The coronavirus disease (COVID-19) pandemic has posed challenges to the global health care community, affecting the management of upper urinary tract stones.

Materials and methods
This retrospective study involved 9 Italian centers. We compared the 12-month period prior to COVID-19 (March 1, 2019, to February 28, 2020; Period A) with the COVID-19 period (March 1, 2020, to February 28, 2021, Period B). This study aimed to compare outcomes during Periods A and B, specifically focusing on the overall number of treatments, rate of urgent/elective cases, and operational complexity.

Results
A total of 4018 procedures were collected, comprising 2176 procedures during Period A and 1842 during Period B, indicating a loss of 15.35% (p < 0.001). In the elective cases, 1622 procedures were conducted in Period A, compared with 1280 in Period B, representing a 21.09% reduction in cases (p = 0.001). All types of stone treatments were affected: extracorporeal shock wave lithotripsy (−29.37%, p = 0.001), percutaneous nephrolithotomy (−26.47%, p = 0.008), retrograde surgeries for renal stones (−10.63%, p = 0.008), and semirigid ureterolithotripsy (−24.86%, p = 0.008). Waiting lists experienced significant delays during Period B. The waiting time (WT) for elective procedures increased during Period B (p < 0.001). For ureteral stones, the mean WT in Period A was 61.44 days compared with 86.56 days in Period B (p = 0.008). The WT for renal stones increased from 64.96 days in Period A to 85.66 days in Period B for retrograde intrarenal surgery (p = 0.008) and from 96.9 days to 1103.9 days (p = 0.035) for percutaneous nephrolithotomy procedures.

Conclusions
Our study demonstrates that COVID-19 significantly disrupted endourological services across the country. Our data underline how patients received treatment over a prolonged period, potentially increasing the risk of stone-related complications and patient discomfort.
Venous thromboembolism testing practices after orthopaedic trauma: prophylaxis regimen does not influence testing patterns
Authors: Haac Bryce E. , O'Hara Nathan N. , Haut Elliott R. , Manson Theodore T. , Slobogean Gerard P. , O'Toole Robert V. , Stein Deborah M. ,   ADAPT Investigators
Published: April 2024

Abstract

Objectives:
To determine venous thromboembolism (VTE) testing patterns in an orthopaedic trauma population and to evaluate for differences in VTE surveillance by prophylaxis regimen through a secondary analysis of the ADAPT trial.

Design:
Prospective randomized trial.

Setting:
Level I trauma center.

Patients:
Three hundred twenty-nine adult (18 years and older) trauma patients presenting with an operative extremity fracture proximal to the metatarsals/carpals or any pelvic or acetabular fracture requiring VTE prophylaxis.

Intervention:
VTE imaging studies recorded within 90 days post injury.

Main Outcome Measurements:
Percentage of patients tested for VTE were compared between treatment groups using Fisher's exact test. Subsequently, multivariable regression was used to determine patient factors significantly associated with risk of receiving a VTE imaging study.

Results:
Sixty-seven patients (20.4%) had VTE tests ordered during the study period. Twenty (29.9%) of these 67 patients with ordered VTE imaging tests had a positive finding. No difference in proportion of patients tested for VTE by prophylaxis regimen (18.8% on aspirin vs. 22.0% on LMWH, P = 0.50) was observed. Factors associated with increased likelihood of VTE testing included White race (adjusted odds ratio [aOR]: 2.61, 95% CI: 1.26–5.42), increased Injury Severity Score (aOR for every 1-point increase: 1.10, 95% CI: 1.05–1.15), and lower socioeconomic status based on the Area Deprivation Index (aOR for every 10-point increase: 1.14, 95% CI: 1.00–1.30).

Conclusions:
VTE surveillance did not significantly differ by prophylaxis regimen. Patient demographic factors including race, injury severity, and socioeconomic status were associated with differences in VTE surveillance.

Level of Evidence:
Level I, Therapeutic.
Systemic low-grade C-reactive protein is associated with proximal symptom spread in carpal tunnel syndrome
Authors: Zvonickova Karolina , Rhee Amber , Sandy-Hindmarch Oliver , Furniss Dominic , Wiberg Akira , Schmid Annina B. 
Published: April 2024

Abstract

Introduction:
Neuropathic pain is a highly prevalent condition associated with persistent disability. Some patients with neuropathic pain experience symptom spread outside neuroanatomical boundaries; these patients report more severe sensory symptoms and greater disability. However, the mechanisms behind such symptom spread are not fully understood.

Objective:
We used pre-surgical carpal tunnel syndrome (CTS) as a human model system of neuropathic pain to identify differences in the concentration of serologic inflammatory mediators between patients with CTS with territorial symptoms and those with proximal symptom spread to either the elbow or shoulder/neck.

Methods:
We performed a post-hoc analysis, comparing levels of serologic inflammatory mediators in a discovery cohort among 3 symptoms spread profiles (n = 55; n = 25 no spread, n = 21 spread to elbow, n = 9 spread to shoulder/neck). We then de-novo analysed the significantly dysregulated mediators in an independent validation cohort (n = 72; n = 34 no spread, n = 16 spread to elbow, n = 22 spread to shoulder/neck).

Results:
The discovery cohort revealed higher serum concentrations of C-reactive protein (CRP) and interleukin-6 in patients with any symptom spread proximal to the wrist; interferon-γ was higher in patients with symptom spread to the elbow compared with those without proximal spread. The validation study replicated the association of higher CRP concentrations in patients with proximal spread to the elbow (no spread: median [interquartile range] 2.5 [5.4]; spread to elbow 6.2 [4.6]; spread to shoulder/neck 2.6 [3.7], P = 0.006). No other markers replicated in the validation cohort.

Conclusions:
Our findings suggest that proximal symptom spread in the context of neuropathic symptoms is associated with low-grade inflammation.
Construction industry changes induced by the COVID-19 pandemic
Authors: Kim Kyudong , Tiedmann Helena R. , Faust Kasey M. 
Published: April 2024

PurposeThe COVID-19 pandemic caused significant societal changes and altered how much of the construction industry operates. This study investigates the impacts of pandemic-related changes, how these changes may apply to different companies, and which changes should continue post-pandemic.Design/methodology/approachWe aim to identify pandemic-driven changes that have affected the construction workplace and the advantages and challenges associated with them. We then make recommendations for what could and should endure through the pandemic and beyond, and under what circumstances. To achieve this objective, we conducted both qualitative and quantitative analyses of 40 semi-structured interviews with US-based construction professionals.FindingsIdentified through these interviews were 21 pandemic-driven changes across six categories: management and planning, technology, workforce, health and safety, supply chain, and contracts. This study noted both positive and negative impacts of the changes on cost, schedule, productivity, collaboration, employee retention, flexibility, quality, and risk mitigation. Participants indicated that some changes should remain after the pandemic and others (e.g. select safety measures, schedule adjustments) should be temporary.Originality/valueBy incorporating these lessons learned into recommendations, the findings of this study will help businesses identify and implement the most appropriate improvements for their organizations. The findings also provide policymakers with valuable insights on how to promote innovation in the construction industry and potentially enact more effective policies during crises to drive long-term improvements.
PFoods: selecting a segment for a sustainable product
Authors: Dani Vinit Vijay , Ramesh Avadhanam , Rishi Bikramjit 
Published: April 2024

Learning outcomes
After working on the assignment questions, the learners can achieve the following learning outcomes: understand the buying behavior towards sustainable products in the context of mindful consumption and product characteristics, appraise the market segmentation and positioning strategy of a sustainable business, understand the application of 5C’s framework for a sustainable business and critically evaluate a new sustainable business’s challenges in the emerging business environment.

Case overview/synopsis
Dr Joe Fenn, founder and director of PFoods, with extensive experience in the pharma industry overseas, observed a decline in the consumption of traditional dairy foods. Alternative plant foods come as a savior to people who are lactose intolerant and offer a host of health benefits with low environmental impact. Riding on the waves of veganism and sustainable foods, he saw an opportunity in India. PFoods developed and launched two products, namely, Just Plants (plant-based milk alternative) and Plotein (plant-based protein alternative), in collaboration with scientists at the Indian Institute of Science, a premier scientific institution in India, and PMEDS (PreEmptive Meds), a US-based nutraceutical Company. PFoods launched and pilot-tested Just Plant, a dairy alternative substitute for milk in select reputed organizations in Bangalore. The upcoming challenges for Fenn would be to select the right segment, educate the market and position the product that would resonate well with the target customers.

Complexity academic level
The case study suits undergraduate and graduate courses such as marketing management, sustainable marketing and sustainable business. The case study can also be used in entrepreneurship management and entrepreneurial marketing courses to introduce the challenges of a sustainable startup. The case study highlights the marketing challenges faced by the disruptive and growing plant-based foods or alternative dairy industry in emerging markets.

Supplementary materials
Teaching notes are available for educators only.

Subject code
CSS 8: Marketing.
Social proof: empowering social commerce through social validation
Authors: Patwa Nitin , Gupta Monika , Mittal Amit 
Published: April 2024

Purpose
This study aims to examine the impact of consumer risk appetite, biases (specifically negative recency bias), and the importance of reviews in enhancing information quality. By analyzing these variables, the authors gain insights into their role in enriching the overall information spectrum available to consumers. The findings contribute to a better understanding of how risk appetite, biases and consumer reviews shape the quality of information.

Design/methodology/approach
The questionnaire assessed the relationship between dependent and independent variables by asking participants to rate their experiences in relevant scenarios. Variance-based structural equation modeling with the ADANCO program was used to examine the data. ADANCO software is used explicitly for variance-based structural equation modeling. To evaluate research models and test hypotheses, partial least square path modeling is used.

Findings
The efficiency of reviews and ratings is greatly influenced by consumer risk appetite. Businesses should focus on clients who are willing to take risks and balance positive and negative feedback. It is essential to comprehend how customers understand reviews. Credibility is increased by taking biases into account and encouraging unbiased criticism. Promoting thorough reviews strengthens influence. Monitoring and making use of these elements improve online reputation and commercial success.

Research limitations/implications
The research has limitations due to the simplicity of the attributes taken into account and the requirement for a larger sample size. Overcoming barriers to promote consistent client feedback is essential, and tailored emails can help with assessment generation. Increased customer participation in writing evaluations can be achieved by removing obstacles and highlighting the advantages of participation.

Originality/value
Businesses and buyers rely on this “organically” generated content as the basis of their promotional strategy and buying decisions. Most of the research is related to consumer reviews, their behavior and the importance of social validation. However, some critical aspects related to this need further investigation.
Insights on emotional labour research: a topic modelling approach
Authors: Trivedi Shrawan Kumar , Chalapathi Dhurjati Shesha , Srivastava Jaya , Singh Shefali , Deb Roy Abhijit 
Published: April 2024

Purpose
Emotional labour (EL) is a complex phenomenon that has received increasing attention in recent years due to its impact on employee’s well-being and job satisfaction. For a comprehensive understanding of the evolving field of EL, it is important to extract different research trends, new developments and research directions in this domain. The study aims to reveal 13 prominent research topics based on the topic modelling analysis.

Design/methodology/approach
Using latent Dirichlet allocation (LDA) method, topic modelling is done on 1,462 journal research papers published between 1999 and 2023, extracted from the Scopus database using the keyword “EL”.

Findings
The analysis identifies several emerging trends in EL research, including emotional regulation training and job redesign. Similarly, the topics like EL strategies, cultural differences and EL, EL in hospitality, organizational support and EL, EL and gender and psychological well-being of nursing workers are popular research topics in this domain.

Research limitations/implications
The findings provide valuable insights into the current state of EL research and can provide a direction for future research as well as assist organizations to design practices aimed at improving working conditions for employees in various industries.

Originality/value
Topic modelling on emotional labor is done. The paper identifies specific topics or clusters related to emotional labor, quantifies these topics using topic modeling, adds empirical rigor, and allows for comparisons across different contexts.