bluuebunny/crossref_metadata_2025_split huggingface dataset:
Projections from the paraventricular nucleus of the thalamus to the forebrain, with special emphasis on the extended amygdala
Authors: Li Sa , Kirouac Gilbert J. 
Published: November 2007

AbstractThe paraventricular nucleus of the thalamus (PVT) is part of a group of midline and intralaminar thalamic nuclei implicated in arousal and attention. This study examined the connections between the PVT and the forebrain by using the retrograde tracer cholera toxin B (CTb) and the anterograde tracer biotin dextran amine (BDA). The anterior and posterior regions of the PVT were found to send a dense projection to the nucleus accumbens. The posterior PVT was also found to provide a strong projection to the lateral bed nucleus of the stria terminalis (BST), interstitial nucleus of the posterior limb of the anterior commissure (IPAC), and central nucleus of the amygdala (CeA), regions associated with the extended amygdala. In contrast, the anterior PVT was found to send a weaker projection to the extended amygdala. The basolateral nucleus of the amygdala and the medial prefrontal cortex were found to receive a relatively weak projection from the PVT, and other regions of the BST and amygdala were found to be poorly innervated by the PVT. In addition, the PVT was found to innervate regions in the extended amygdala that contained corticotropin‐releasing factor (CRF) neurons, many of which were found to receive apparent contacts from PVT fibers. The projection from the PVT to the nucleus accumbens and extended amygdala places the PVT in a key anatomical position to influence adaptive behaviors as well as the physiological and neuroendocrine responses associated with these behaviors. J. Comp. Neurol. 506:263–287, 2008. © 2007 Wiley‐Liss, Inc.
Striatal projections of the vagal‐responsive region of the thalamic parafascicular nucleus in macaque monkeys
Authors: Ito S. , Craig A.D. (BUD) 
Published: November 2007

AbstractWe recently reported that the thalamic parafascicular nucleus (Pf) in monkeys is strongly activated by vagus nerve afferents. The main forebrain target of Pf is the striatum, but the specific striatal regions receiving visceral input via this pathway are unknown. We examined the projections of this region by injecting anterograde tracers into the vagus evoked potential (VEP) focus in Pf of macaque monkeys. The VEP was strongest lateral and anterior to the habenulointerpeduncular tract, but it was distributed across the entire horizontal extent of the ventral half of Pf. All injections produced labeled terminals in the caudate (Cd), especially the Cd tail and the adjacent ventral posterior Pu. Terminations occurred throughout the Cd head and body but spared the most anterior and dorsolateral parts. Injections in more anterior and lateral portions of Pf produced progressively more terminations in Pu, mainly in the precommissural region and the medial aspect of posterior Pu. Dual injections of different tracers revealed overlapping projections with interdigitated strands of striatal terminations from separate regions of Pf as well as the posteromedial to anterolateral topographic gradient of increasing Pf projections to Pu. An injection in the most anteromedial portion of Pf produced strong labeling in the ventral striatum. Thus, Pf transmits viscerosensory information to the “associative” and “limbic” territories of the striatum. These findings suggest the broad involvement of homeostatic afferent activity in striatal function and perhaps a role for the striatum in autonomic function. J. Comp. Neurol. 506:301–327, 2008. © 2007 Wiley‐Liss, Inc.
Embryonic and postnatal development of microglial cells in the mouse retina
Authors: Santos Ana M. , Calvente Ruth , Tassi Mohamed , Carrasco Maria‐Carmen , Martín‐Oliva David , Marín‐Teva José L. , Navascués Julio , Cuadros Miguel A. 
Published: November 2007

AbstractMacrophage/microglial cells in the mouse retina during embryonic and postnatal development were studied by immunocytochemistry with Iba1, F4/80, anti‐CD45, and anti‐CD68 antibodies and by tomato lectin histochemistry. These cells were already present in the retina of embryos aged 11.5 days (E11.5) in association with cell death. At E12.5 some macrophage/microglial cells also appeared in peripheral regions of the retina with no apparent relationship with cell death. Immediately before birth microglial cells were present in the neuroblastic, inner plexiform (IPL), and ganglion cell (GCL) layers, and their distribution suggested that they entered the retina from the ciliary margin and the vitreous. The density of retinal microglial cells strongly decreased at birth, increased during the first postnatal week as a consequence of the entry of microglial precursors into the retina from the vitreous, and subsequently decreased owing to the cessation of microglial entry and the increase in retina size. The mature topographical distribution pattern of microglia emerged during postnatal development of the retina, apparently by radial migration of microglial cells from the vitreal surface in a vitreal‐to‐scleral direction. Whereas microglial cells were only seen in the GCL and IPL at birth, they progressively appeared in more scleral layers at increasing postnatal ages. Thus, microglial cells were present within all layers of the retina except the outer nuclear layer at the beginning of the second postnatal week. Once microglial cells reached their definitive location, they progressively ramified. J. Comp. Neurol. 506:224–239, 2008. © 2007 Wiley‐Liss, Inc.
Deletion of voltage‐gated channel affects glomerular refinement and odorant receptor expression in the mouse olfactory system
Authors: Biju K.C. , Marks David Ronald , Mast Thomas Gerald , Fadool Debra Ann 
Published: November 2007

AbstractOlfactory sensory neurons (OSNs) expressing a specific odorant receptor (OR) gene send axonal projections to specific glomeruli, creating a stereotypic olfactory sensory map. Odorant receptor sequence, G‐protein cAMP signaling, and axon guidance molecules have been shown to direct axons of OSNs toward central targets in the olfactory bulb (OB). Although the OR sequence may act as one determinant, our objective was to elucidate the extent by which voltage‐dependent activity of postsynaptic projection neurons in the OB centrally influences peripheral development and target destination of OSNs. We bred OR‐tagged transgenic mice to homozygosity with mice that had a gene‐targeted deletion of the Shaker potassium ion channel (Kv1.3) to elucidate how activity modulates synaptic connections that formulate the sensory map. Here we report that the Kv1.3 ion channel, which is predominantly expressed in mitral cells and whose gene‐targeted deletion causes a “super‐smeller” phenotype, alters synaptic refinement of axonal projections from OSNs expressing P2, M72, and MOR28 ORs. Absence of Kv1.3 voltage‐gated activity caused the formation of small, heterogeneous, and supernumerary glomeruli that failed to undergo neural pruning over development. These changes were accompanied by a significant decrease in the number of P2‐, M72‐, and MOR28‐expressing OSNs, which contained an overexpression of OR protein and G‐protein Golf in the cilia of the olfactory epithelium. These findings suggest that voltage‐gated activity of projection neurons is essential to refine primary olfactory projections and that it regulates proper expression of the transduction machinery at the periphery. J. Comp. Neurol. 506:161–179, 2008. © 2007 Wiley‐Liss, Inc.
Solution strategies for coupled conduction/radiation problems
Authors: Hogan R. E. , Gartling D. K. 
Published: November 2007

AbstractSolution strategies and algorithms for solving coupled systems of equations that arise from the finite element formulation of heat conduction and enclosure radiation problems are presented and evaluated. Solution methods that vary from sequential equation processing to fully coupled procedures are tested for convergence, robustness and computational efficiency, in both transient and time‐independent modeling situations. Published in 2007 by John Wiley & Sons, Ltd.
Computation of stress intensity factors for through cracks in plates using p‐version finite element method
Authors: Munaswamy K. , Pullela Ramalakshmi 
Published: November 2007

AbstractThe present study concerns the analysis of bending of plates and shells subjected to various boundary conditions and load. Bending stress intensity factors for plates containing through‐thickness crack under edge bending load are evaluated. To accomplish this task, hierarchical degenerated plate/shell and crack‐tip singular plate/shell elements were developed.The hierarchical degenerated plate shell element has four corner nodes, four mid‐side nodes and one central node on the mid‐surface of the shell geometry with five degrees of freedom at each node. p‐Version shape functions up to order seven were used for defining the displacement field. Enriching the displacement field with the asymptotic displacement field near the crack tip, a crack‐tip singular plate/shell element was developed. Some benchmark problems were analyzed and compared. Analyses were performed to obtain the stress intensity factors of plate with through‐thickness crack using singular hierarchical degenerated plate/shell element around the crack tip. Numerical results obtained from the present element formulations are compared with analytical/numerical solutions available from literature. It is inferred that numerical results are in good agreement with the benchmark plate and shell problems. Copyright © 2007 John Wiley & Sons, Ltd.
Redox Kinetics of Ceria‐Based Mixed Oxides in Selective Hydrogen Combustion
Authors: Blank Jan Hendrik , Beckers Jurriaan , Collignon Paul F. , Rothenberg Gadi 
Published: November 2007

AbstractCeria‐based mixed oxides, in which about 10 mol % of the cerium is replaced by another metal, catalyze the selective combustion of hydrogen from a mixture of hydrogen, propane, and propene at 550 °C. This makes them attractive catalysts for the oxidative dehydrogenation of propane. Hydrogen combustion shifts the equilibrium to the products side, supplies energy for the endothermic dehydrogenation, and simplifies product separation. The type of metal added has an important effect on the catalytic properties. To gain insight into the process, a set consisting of six mixed oxides was synthesized and the catalytic properties and redox behavior were tested. The mixed oxides generally release more oxygen than plain ceria. Mixed oxides containing Bi, Cu, Fe, Pd or Ca release between 1.6 and 2.0 mg of oxygen per 100 mg sample (compared to only 1.2 mg for plain ceria). This result is important for reactions in which the catalyst acts as an oxygen reservoir, such as selective hydrogen combustion. The temperature at which oxygen is released is generally lower for the mixed oxides, and varies from 110 °C (for Cu‐CeO2) to 550 °C (for Ca‐CeO2), which enables catalytic applications over a wide temperature range. The reduction rate at 550 °C is related to the reduction onset of the catalysts. Those catalysts with a relatively low reduction temperature, such as Cu‐, Mn‐, Bi‐, and Pb‐CeO2, show a high reduction rate, whereas those with a high reduction temperature, such as Ca‐CeO2, Fe‐CeO2, and plain ceria, reduce at a slower rate. The latter catalysts also have a low selectivity towards hydrogen combustion. The influence of the catalyst composition and crystallite size on the activity and selectivity is discussed.
From nature to nurture, and back again
Authors: Miller David B. 
Published: November 2007

AbstractGilbert Gottlieb's developmental theory views organismic development as a multilevel system involving ongoing transactions among different levels of organization. Here, I review his conception of development as it has been influenced historically and has guided several lines of empirical inquiry focusing on auditory communication in birds. Ecological factors are considered an important means of identifying possible nonlinear (i.e., subtle or nonobvious) forms of experience that play a significant role in species‐typical development. Failure to consider such nonlinearities, along with obvious linear influences, undermines the developmental point of view that Gottlieb advocated as a means of teasing apart the intricate nature of organismic development. © 2007 Wiley Periodicals, Inc. Dev Psychobiol 49: 770–779, 2007.
The dynamics of development and evolution: Insights from behavioral embryology
Authors: Lickliter Robert 
Published: November 2007

AbstractThe perspective that features of species‐typical behavior could be traced to experience that occurred prenatally was raised by Zing‐Yang Kuo [1921Journal of Philosophy 18: 645–664] early in the last century and Gilbert Gottlieb subsequently elaborated on and provided empirical support for this idea over the course of more than four decades of innovative psychobiological research. Although we are still a long way from fully understanding the specific pathways and processes by which prenatal experience can influence postnatal development, Gottlieb's research with precocial birds provided significant insights into the conditions and experiences of prenatal development involved in the achievement of species‐typical perception and behavior. In particular, his elegant series of studies on the development of species identification in ducklings documented how the features and patterns of recurring prenatal sensory experience (including self‐stimulation) guide and constrain the young individual's selective attention, perception, learning, and memory during both prenatal and postnatal periods. I review how this body of research supports the view that the structure and functions of the developing organism and its developmental ecology together form a relationship of mutual influence on the emergence, maintenance, and transformation of species‐typical behavior. I also explore how Gottlieb's empirical demonstrations of the prenatal roots of so‐called “instinctive” behavior provided a foundation for his conceptual efforts to define the links between developmental and evolutionary change. © 2007 Wiley Periodicals, Inc. Dev Psychobiol 49: 749–757, 2007.
Gilbert Gottlieb: Intermediator between psychology and evolutionary biology
Authors: Rosenblatt Jay S. 
Published: November 2007

AbstractThis article describes and evaluates Gilbert Gottlieb's role as an intermediator between psychology and evolutionary biology. He proposed that altered developmental conditions gave rise to new behavioral phenotypes (behavioral neophenotypes) that could provide the basis for initiating speciation. As an example, Gottlieb cited sympatric speciation of two species of fruit flies (Rhageletis pomella), which he believed was based on an ontogenetic shift in pupal feeding on apples or hawthorn fruit which determined their adult selection of apple or hawthorn trees for ovipositing. Recent evidence has provided additional links in the process of speciation of these fruit flies. Unlike other efforts to incorporate evolution in psychology, Gottlieb's theoretical contribution was based on actual evolutionary processes including recent developments in the field of evo‐devo. © 2007 Wiley Periodicals, Inc. Dev Psychobiol 49: 800–807, 2007.
Gilbert Gottlieb's theory of probabilistic epigenesis: Probabilities and realities in development
Authors: Valsiner Jaan 
Published: November 2007

AbstractGilbert Gottlieb's theory of probabilistic epigenesis is a fertile ground for further theoretical construction in developmental science. It fills in the gap in the domineering empiricism and honoring of inductive generalization that dominates psychology in the beginning of the 21st century, by offering a basic deductive framework for guiding the efforts of developmental science. It was based on a program of careful experimental investigations of the early avian ontogenies—later to be generalized to the developmental processes as a generic phenomenon. Further development of his theory takes the form of (a) explicating the different meanings of probabilism in his model, and (b) extending his multi‐level system to include psychological and social levels of organization. Gottlieb's contribution allows for a new synthesis of contemporary epigenetics and developmental science, and sets up major challenges for the methodology of research on development. © 2007 Wiley Periodicals, Inc. Dev Psychobiol 49: 832–840, 2007.
The innate and the acquired: Useful clusters or a residual distinction from folk biology?
Authors: Bateson Patrick , Mameli Matteo 
Published: November 2007

AbstractThe idea of the innate and the acquired is a part of folk‐biology but is also used by biologists, psychologists and cognitive scientists in their disciplines. Are they right to do so? Innateness is often defined by appealing to the role of genes in development, to the role of Darwinian evolution in shaping developmental processes, to the non‐involvement of learning during development, to developmental robustness, and to modularity. We argue that all such definitions are unsatisfactory. Some are unsatisfactory because they are based on simplistic and empirically outmoded views of development. Others are empirically defensible but are unsatisfactory because they do not capture the full breadth of the use of the term “innate” and, due to this restriction, they can easily lead to inferential mistakes. The definition of acquired behavior has been used with greater sophistication and is generally regarded as being heterogeneous. Nevertheless, in as much as the overall category has been seen in opposition to the innate, it has been an obstacle to a thorough investigation of how behavior develops. We suggest that a useful way forward is to examine whether or not the empirically well‐established properties often associated with the concept of innate and the concept of acquired form theoretically useful clusters. This path leads to a much fuller appreciation of the view favored by Gilbert Gottlieb, according to which development involves the continuous interplay of the organism (and its genes) with its environment. © 2007 Wiley Periodicals, Inc. Dev Psychobiol 49: 818–831, 2007.
Adult glial precursor proliferation in mutant SOD1G93A mice
Authors: Magnus Tim , Carmen Jessica , Deleon Jessica , Xue Haipeng , Pardo Andrea C. , Lepore Angelo C. , Mattson Mark P. , Rao Mahendra S. , Maragakis Nicholas J. 
Published: November 2007

AbstractThe focus of most neurodegenerative disease studies has been on neuronal death in particular subpopulations of the central nervous system. The associated response of glial populations has been ascribed the term “reactive astrocytosis.” This has been defined as the proliferation of astrocytes accompanied by cellular hypertrophy and changes in gene expression following injury to the central nervous system. Yet the significance of that response to disease course is debated. In both human ALS and in the SOD1G93A mouse model of ALS, reactive astrocytosis is a hallmark of the disease—particularly at endstage. The brain also harbors immature progenitors which have the capacity for differentiation into both glial and neuronal lineages. We examined whether glial progenitors in the adult spinal cord of SOD1G93A mice become activated and contribute the astroglial response observed in this model. We found that the glial progenitor proteoglycan NG2 is increased in parallel with GFAP during the symptomatic phase of the disease and that there is a differential in vitro response of SOD1G93A glial progenitors to inflammatory cytokines when compared to wildtype mouse glial progenitors. This response was accompanied by the proliferation of glial progenitors but not mature GFAP+ astrocytes, through the translocation of the transcription factor Olig2 from the nucleus to the cytoplasm—resulting in astrocyte differentiation. These data suggest that adult glial progenitors from SOD1G93A mice differentially respond to inflammatory cytokines and contribute to the observed reactive astrocytosis observed in SOD1G93A mouse lumbar spinal cord. © 2007 Wiley‐Liss, Inc.
Adult T‐cell leukemia/lymphoma with multiple integration of HTLV‐1 provirus presenting as an isolated paranasal sinus tumor: A case report
Authors: Nagasaki Akitoshi , Miyagi Takashi , Taira Tamiko , Shinhama Akihiko , Kojya Shizuo , Suzuki Mikio , Aonahata Miyuki , Yoshimi Naoki , Takasu Nobuyuki 
Published: November 2007

AbstractBackground.Adult T‐cell leukemia/lymphoma (ATLL) is a highly aggressive T‐cell lymphoma and etiologically associated with human T‐lymphotropic virus type 1 (HTLV‐1). Patients with ATLL commonly present with leukemic changes, systemic lymphadenopathy, and/or extranodal lesion and have very poor prognosis.Methods and Results.We describe a rare case of ATLL presenting as an isolated paranasal mass. Southern blot analysis of the biopsied specimens demonstrated multiple integration bands of HTLV‐1 provirus of different intensities. Chemotherapy resulted in complete resolution of the paranasal mass. Thereafter, the patient showed an indolent clinical course with leukemic changes and pulmonary and cutaneous ATLL lesions and remains alive more than 5 years from diagnosis.Conclusion.ATLL should be included in the differential diagnosis of sinonasal lymphoma, although the event is rare. Multiple HTLV‐1 provirus integrations of different intensities may be indicative of good prognosis for ATLL. © 2007 Wiley Periodicals, Inc. Head Neck, 2008
Experience of palliative care for patients with head and neck cancer through the eyes of next of kin
Authors: Ledeboer Quirine C. P. , Offerman Marinella P. J. , van der Velden Lilly‐Ann , de Boer Maarten F. , Pruyn Jean F. A. 
Published: November 2007

AbstractBackground.Little is known about how palliative care is experienced by patients with head and neck cancer and their relatives. The aim of this retrospective study was to analyze this care from the point of view of surviving relatives.Methods.Fifty‐five surviving relatives of patients with head and neck cancer treated at our department were enrolled in this study. Forty‐five returned a completed questionnaire.Results.Medical treatment during the palliative stage was judged as sufficient in most cases, but was often felt to be intrusive. The majority of patients had more need for psychosocial and physical support. Contact between head and neck surgeon and patient was sufficient. Many relatives found information about the terminal stage unsatisfactory.Conclusion.Not all aspects of palliative care for head and neck patients are sufficient, and improvements are, in our setting, necessary, specifically within the psychosocial field. This supports the initiation of our Expert Center to improve quality of life in the palliative stage. © 2007 Wiley Periodicals, Inc. Head Neck, 2008