bluuebunny/crossref_metadata_2025_split huggingface dataset:
“Technology has allowed us to do a lot more but it’s not necessarily the panacea for everybody”: Family physician perspectives on virtual care during the COVID-19 pandemic and beyond
Authors: Hedden Lindsay , Spencer Sarah , Mathews Maria , Gard Marshall Emily , Lukewich Julia , Asghari Shabnam , Gill Paul , McCracken Rita K. , Vaughan Crystal , Wong Eric , Buote Richard , Meredith Leslie , Moritz Lauren , Ryan Dana , Schacter Gordon 
Published: February 2024

Introduction
Early in the COVID-19 pandemic, Canadian primary care practices rapidly adapted to provide care virtually. Most family physicians lacked prior training or expertise with virtual care. In the absence of formal guidance, they made individual decisions about in-person versus remote care based on clinical judgement, their longitudinal relationships with patients, and personal risk assessments. Our objective was to explore Canadian family physicians’ perspectives on the strengths and limitations of virtual care implementation for their patient populations during the COVID-19 pandemic and implications for the integration of virtual care into broader primary care practice.

Methods
We conducted semi-structured qualitative interviews with family physicians working in four Canadian jurisdictions (Vancouver Coastal health region, British Columbia; Southwestern Ontario; the province of Nova Scotia; and Eastern Health region, Newfoundland and Labrador). We analyzed interview data using a structured applied thematic approach.

Results
We interviewed 68 family physicians and identified four distinct themes during our analysis related to experiences with and perspectives on virtual care: (1) changes in access to primary care; (2) quality and efficacy of care provided virtually; (3) patient and provider comfort with virtual modalities; and (4) necessary supports for virtual care moving forward.

Conclusions
The move to virtual care enhanced access to care for select patients and was helpful for family physicians to better manage their panels. However, virtual care also created access challenges for some patients (e.g., people who are underhoused or living in areas without good phone or internet access) and for some types of care (e.g., care that required access to medical devices). Family physicians are optimistic about the ongoing integration of virtual care into broader primary care delivery, but guidance, regulations, and infrastructure investments are needed to ensure equitable access and to maximize quality of care.
Development of an intervention for reducing infant bathing frequency
Authors: Goldsmith Lucy P. , Perkin Michael R. , Wahlich Charlotte , Chandrasekaran Lakshmi , Cornelius Victoria , Boyle Robert J. , Flohr Carsten , Roberts Amanda , Willis Kathryn , Ussher Michael 
Published: February 2024

Background
Bathing babies less frequently and intensively in the first six months of life may prevent eczema, but this has not yet been definitively tested in a randomised controlled trial. Such a trial would require evidence-based support to help parents engage with a minimal bathing routine. The present study reports the development of this support.

Methods
We adopted a four-stage design process: (i) Pregnant women and their families (n = 31) were interviewed to ascertain key barriers and facilitators towards following the minimal bathing intervention. (ii) These barriers and facilitators were mapped to behaviour change techniques, focussing on the intervention types of education, persuasion and environmental restructuring, alongside appropriate modes of delivery, and prototype intervention materials were developed. (iii) We iteratively refined these materials in a workshop with multidisciplinary experts and Patient and Public Involvement and Engagement (PPIE) representatives (n = 13) and an (iv) intervention walkthrough with families (n = 5). The design process was informed by the Behaviour Change Wheel, Theoretical framework of acceptability and the Template for intervention description and replication.

Results
Social influences and motivational factors are likely to influence both uptake and adherence to the intervention. Anticipated emotional reward from participating in research for the benefit of others was indicated to be a strong facilitator for intervention uptake. Alternatives to bathing, having fun with the baby and the night-time routine, alongside family support, were notable facilitators suggested to aid adherence to the intervention. Barriers included hygiene concerns and anticipated negative social appraisal. Barriers and facilitators were mapped to thirty-six behaviour change techniques, focussing on the intervention types of education, persuasion and environmental restructuring, all of which were embedded into the package of support. The prototype intervention materials received positive feedback from the expert workshop and study walkthrough with families. The final package of support comprises printed and digital prompts and cues, a study booklet, video, and digital tool for self-monitoring.

Conclusions
The intervention design process incorporated the ‘real world’ views and experiences of families, experts and PPIE representatives, alongside criteria for designing behavioural interventions. The effectiveness of the package of support will be tested in a feasibility trial and embedded process evaluation.
Small Bowel Perforation Due to an Unusual Foreign Body
Authors: Anand Kamalam  , Sugatri Peruka  , Prathap Chouhan M.  , Pratyusha Seelam  , Madiha Taher  
Published: February 2024

Gastrointestinal perforation is one of the most common causes of acute abdomen presenting to the casualty. However, gastrointestinal perforation due to ingestion of foreign body is rare and is usually encountered in children, psychiatric patients and in alcoholics. Most of the foreign bodies pass through the GI tract without any complications. Only about 1% are known to cause complications such as perforation. Fish or chicken bones, dentures, toy parts, coins, toothpicks are the most commonly encountered foreign bodies. In this report, we present a case of a 60-year-old male who presented to the emergency department with acute abdomen secondary to ingestion of an unusual foreign body that lead to perforation and underwent exploratory laparotomy for removal of the foreign body.
Gastrointestinal perforation is one of the most common causes of acute abdomen presenting to the casualty that needs a timely surgical intervention.[1] Important sites of gastrointestinal perforation are stomach, duodenum, small bowel (jejunum, small intestine), appendix, colon and rectum.
The most common causes of gastrointestinal perforation include peptic ulcer disease, diverticulitis, carcinomas, IBD, ischemia of bowel wall and infrequently foreign bodies.[2]
Foreign body ingestion as seen in children is unintentional and can be deliberate in psychiatric patients.[3] In general, many of these foreign bodies travel through the gastrointestinal tract without causing complications. Only about 1% cases of ingested foreign bodies cause complications such as hollow viscus obstruction and/ or perforation which are usually life threatening and have poorer outcomes if diagnosis is delayed.[4,5] CT is the imaging tool of choice. Such conditions require immediate surgical intervention such as exploratory laparotomy or laparoscopic or endoscopic removal can be attempted in case of stomach or duodenal foreign bodies.
Here in the following case report, we present an atypical case who arrived at the emergency room with acute abdomen following a foreign body consumption and underwent exploratory laparotomy for retrieval of foreign body.
Current views on the treatment of insulinoma
Authors: Chernykh T. M. , Malyugin D. A. , Khachaturov M. V. , Shefer A. A. , Zoloedov V. I. 
Published: February 2024

Relevance: Insulinoma is the most common hormonally active neuroendocrine tumor (NET) of the pancreas. In recent years, there has been a trend towards an increase in the incidence of NET especially insulinoma.Aim: Summarizing and analyzing current data on various approaches to the treatment of insulinoma. Our review includes a comprehensive assessment of the advantages and disadvantages of currently available insulinoma treatment methods in comparison with past experience, as well as a review of promising methods that are not currently widely used.Materials and methods: Analysis of literature from such databases as scientific electronic library elibrary.ru, Pubmed, Google Scholar, MedLine, Scopus and Web of Science.Results: The most common treatment for insulinoma is surgery. For patients with high operative risk, alternative methods such as alcohol ablation, radiofrequency ablation, and tumor embolization may be used. Medications include the use of somatostatin analogues, diazoxide. The literature describes the potential benefit of the use of beta-blockers, phenytoin, glucagon, however, in clinical trials, these drugs have not demonstrated a significant effect. For the treatment of malignant and metastatically advanced insulinoma, targeted therapy (primarily Everolimus), chemotherapy, as well as embolization (including chemoembolization, radioembolization), radiofrequency ablation (RFA), microwave ablation and cryoablation, ultrasound ablation (HIFU), laser ablation, brachytherapy, irreversible electroporation are used.Conclusion: The study of new drugs is an important task for scientists, among medications the most promising are new generations of somatostatin analogues, targeted drugs and chemotherapy drugs. The rare frequency of insulinoma makes it difficult to conduct randomized controlled trials and prospective studies. That is why physicians and scientists need to maintain close contacts with each other and take into account the experience of treating each patient with such disease, which will help develop effective treatment algorithms in the future.
Comparative analysis of bone complications/manifestations in sporadic and MEN1-related primary hyperparathyroidism
Authors: Pylina S. V. , Eremkina A. K. , Elfimova A. R. , Gorbacheva A. M. , Mokrysheva N. G. 
Published: February 2024

BACKGROUND: Multiple endocrine neoplasia type 1 (MEN1) — is a rare syndrome with an autosomal dominant inheritance pattern caused by a mutation in the tumor suppressor gene (MEN1). Parathyroid involvement is the most common MEN1 manifestation resulting in primary hyperparathyroidism (mPHPT). Data on the prevalence and structure of bone disease in mPHPT compared to sporadic one (sPHPT) are often incomplete and contradictory.AIM: The purpose of this study was to compare the severity of bone involvement between mPHPT and sPHPT.MATERIALS AND METHODS: A single-center retrospective study was conducted among young patients in the active phase of PHPT and without prior parathyroidectomy in anamnesis. The analysis included the main parameters of calcium-phosphorus metabolism, bone remodeling markers, as well as an assessment of disease complications. Bone mineral density (BMD) was measured using dual-energy X-ray absorptiometry (DXA) at sites of lumbar spine, femur and radius. Trabecular bone score (TBS) was applied to estimate trabecular microarchitecture. All patients included in the study underwent genetic testing.RESULTS: Group 1 (mPHPT) included 26 patients, and group 2 (sSHPT) included 30 age-matched patients: the median age in group 1 was 34.5 years [25; 39], in group 2 — 30.5 years [28; 36], (p=0.439, U-test). Within group 1, the subgroup 1A (n=21) was formed with patients without other hormone-produced neuroendocrine neoplasms (NEN) in the gastrointestinal tract (GI) and the anterior pituitary gland. The duration of PHPT was comparable in both groups: mPHPT — 1 year [0; 3] versus sPHPT — 1 year [0; 1], (p=0.533, U-test). There were no differences in the main parameters of calcium-phosphorus metabolism, as well as in the prevalence of kidney complications. In the mPHPT group, bone abnormalities were observed significantly more often compared to sPHPT: 54 vs 10% (p=<0.001; F-test). Statistically significant differences were revealed both in BMD and in Z-score values of the femoral neck and total hip, which were lower in the mPHPT group. These differences remained significant when comparing subgroup 1A with sPHPT.CONCLUSION: MEN1-associated PHPT may be accompanied by a more severe decrease in BMD in the femoral neck and total hip compared to sPHPT regardless of the other hormone-producing NEN. Clarifying the role of mutation in the MEN1 gene in these processes requires further study.
Mathematical modelling of COVID-19 dynamics using SVEAIQHR model
Authors: Venkatesh Ambalarajan , Rao Mallela Ankamma , Raj Murugadoss Prakash , Kumar Karuppusamy Arun , Vamsi D. K. K. 
Published: February 2024

Abstract
In this study, we formulate an eight-compartment mathematical model with vaccination as one of the compartments to analyze the dynamics of COVID-19 transmission. We examine the model’s qualitative properties, such as positivity and boundedness of solutions, and stability analysis of the illness-free equilibrium with respect to the basic reproduction number. We estimate ten significant parameters and also compute the magnitude of the basic reproduction number for India by fitting the proposed model to daily confirmed and cumulative confirmed COVID-19 cases in India. Sensitivity analysis with respect to basic reproduction number is conducted, and the main parameters that impact the widespread of disease are determined. We further extend this model to an optimal control problem by including four non-pharmaceutical and pharmaceutical intervention measures as control functions. Our numerical results show that the four control strategy has greater impact than the three control strategies, two control strategies, and single control strategies on reducing the dynamics of COVID-19 transmission.
Biofabrication of silver nanoparticles using Uncaria tomentosa L.: Insight into characterization, antibacterial activities combined with antibiotics, and effect on Triticum aestivum germination
Authors: Alghanmi Reem M. , Hamouda Ragaa A. , Al-Moubaraki Aisha H. , Allouzi Afnan A. , Abuelmagd Muhammad A. 
Published: February 2024

Abstract
Herein, we used the aqueous extract of Uncaria tomentosa L. barks (Cat’s claw bark [CCb]) for the biofabrication of silver nanoparticles (CCb-Ag-NPs). The effects of different parameters (Uncaria tomentosa L. aqueous extract, silver nitrate [AgNO3] ratio, temperature, and pH) on the formation of the nanoparticles were investigated using UV scan as a preliminary tool for the detection of surface plasmon resonance of CCb-Ag-NPs. The optimal ratio was 1:7 (Uncaria tomentosa L. extract: 1 mM AgNO3 solution). Fourier-transform infrared spectroscopy revealed the functional groups of both CCb extract and the CCb-Ag-NPs, whose dispersion and quasispherical morphologies were characterized using scanning electron microscopy and transmission electron microscopy. Particle sizes ranged from 19.2 to 38.5 nm. The zeta potential of CCb-Ag-NPs was −34.44 mV. According to energy-dispersive X-ray analysis, the CCb-Ag-NPs contained 28.87% silver. The formation of Ag-NPs was also confirmed by X-ray diffraction pattern analysis. Pristine CCb-Ag-NPs showed antibacterial activity against three pathogenic bacterial strains: Escherichia coli (ATCC 25922), E. coli (ATCC 8739), and Pseudomonas aeruginosa (ATCC 90274). Antibacterial activity increased significantly after loading CCb-Ag-NPs on antibiotic discs containing meropenem and cefoxitin. Low concentrations of CCb-Ag-NPs also enhanced the germination percentage, coleoptile length, and radical root length of Triticum aestivum.
Use of Crisis Communication Strategies by Food Bank Network During a Global Pandemic
Authors: Haupt Brittany “Brie” , Azevedo Lauren , O’Grady Michael 
Published: February 2024

Abstract
During the novel coronavirus pandemic (COVID-19), nonprofits needed to quickly rethink their strategies concerning the sustainability of their organizations along with communication regarding the crisis. The pandemic presented unique opportunities for understanding how service-oriented nonprofits, who must share timely and accurate information across stakeholders and work closely with partner organizations, can deliver services during crisis periods. Utilizing a case study approach, the focus of this study is the impact of COVID-19 on the Federation of Virginia Food Banks (FVFB), which is a 501(c)(3) nonprofit state association of food banks affiliated with Feeding America, by examining the use of crisis communication strategies utilized or not-utilized during the crisis response and recovery activities. The findings present practical implications for nonprofit organizations and their crisis response and recovery networks and a better understanding of the needs for nonprofit organizations to engage in crisis communication planning for diverse crises and planning resources.
Postcolonial Analysis of Transcultural News Frames: A Case Study of Facebook Rebranding
Authors: Ditlhokwa Gopolang , Cann Victoria Elizabeth 
Published: February 2024

Abstract
This study investigates the portrayal of international technology companies in the media, with a specific focus on Facebook rebranding. Utilizing content analysis and correlational observation, we conducted a comparative analysis of search interests and news frames between Western and African-based news websites following the announcement of Facebook’s rebranding to Meta. Two datasets were examined to assess search interest and sentiment scores based on the positivity, negativity, and neutrality of published stories from selected African and Western countries. The findings reveal the persistence of colonial influences in news coverage, with Western websites demonstrating sympathy and African websites emphasizing conflict-driven narratives. These observations underscore the significance of media diversity and representation in shaping public discourse, particularly in postcolonial contexts characterized by ethnocentrism, poverty, violence, and political instability.
The analyses of human MCPH1 DNA repair machinery and genetic variations
Authors: Oluwole Oluwafemi G. 
Published: February 2024

Abstract
Causal mutations in the MCPH1 gene have been associated with disorders like microcephaly, and recently congenital hearing impairment. This study examined the MCPH1 DNA repair machinery and identified genetic variations of interest in gnomAD database to discuss the biological roles and effects of rare variants in MCPH1-related diseases. Notably, MCPH1 coordinates two of the seven known mechanisms of DNA repair which confirmed its roles in neurogenesis and chromatin condensation. A pathogenic missense variant in MCPH1 p.Gly753Arg, and two pathogenic frameshifts MCPH1 p.Asn189LysfsTer15 and p.Cys624Ter identified in this study, already had entries in ClinVar and were associated with microcephaly. A pathogenic frameshift in MCPH1 p.Val10SerfsTer5 with a loss-of-function flag and a pathogenic stop gained p.Ser571Ter variants with ultra-rare allele frequency (MAF ≤ 0.001) were identified but have not been linked to any phenotype. The predicted pathogenic ultra-rare variants identified in this study, warranty phenotypic discovery, and also positioned these variants or nearby deleterious variants candidate for screening in MCPH1-associated rare diseases.
Dynamic 3-D Visualization System of Sea Flow Field Based on Virtual Reality Technology in the Environment of Internet of Things
Authors: Li Rui 
Published: February 2024

Abstract
Ocean 3-D dynamic visualization is a method to analyze the law of ocean motion by processing complex and changeable ocean data by importing and visualizing. Through 3-D visualization design, the ability to analyze and reconstruct 3-D visualization characteristics of sea area flow field can be improved. To improve the 3-D dynamic visualization effect of ocean flow field and reveal the law of ocean motion, this paper designs a 3-D dynamic visualization system of ocean flow field based on virtual reality technology. Firstly, the framework of the dynamic 3-D visualization system of sea area flow field was designed. On the basis of defining the system development environment, the system software was developed and designed from the aspects of information acquisition module, database model, 3-D reconstruction module, visual simulation module, etc. So far, the design of the 3-D dynamic visualization system of sea area flow field was realized. The simulation results show that the output stability of the design system is good, the visualization ability is strong, and it has certain application values.
Color Compensation Method of 2-D Clothing Image Based on Visual Communication from the Perspective of Internet of Things
Authors: Yin Lei , Liu Jing 
Published: February 2024

Abstract
From the perspective of the Internet of Things, market competition is becoming increasingly fierce, and Internet of Things technology can provide more possibilities for clothing brands’ advertising and marketing strategies, further shaping brand image. However, the color of 2-D clothing images is imbalanced. Therefore, when using the current method for color compensation processing of 2-D clothing images, it is prone to interference from issues such as lighting shadows, uneven brightness, and angle changes. The structural similarity of 2-D clothing images is low, the peak signal-to-noise ratio (PSNR) is low, the standard deviation is low, and the visual effect is poor. The research goal is to solve this problem, and a color compensation method of 2-D clothing image based on visual communication from the perspective of the Internet of Things is proposed. Firstly, the 2-D clothing image is segmented by histogram of oriented gradients feature and exemplar support vector machine classifier, and then the dimension of the image is reduced by weighted subspace probabilistic clustering analysis(WSPCA) algorithm and nonlinear algorithm, and the noise in the image is eliminated by homomorphic filtering method. Finally, the preprocessed image is input into a Gaussian homomorphic filter to complete the color compensation of the 2-D clothing image. Analyzing the experimental results, it can be seen that the proposed algorithm has high structural similarity, high PSNR, high standard deviation, and good visual effect.