bluuebunny/crossref_metadata_2025_split huggingface dataset:
Kaempferol regulates apoptosis and migration of neural stem cells to attenuate cerebral infarction by O‐GlcNAcylation of β-catenin
Authors: Zhang Song , Jiao Honglei 
Published: March 2024

Abstract
Ischemic stroke remains a major cause of disability and death. Kaempferol (Kae) is a neuroprotective flavonoid compound. Thus, this study aimed to explore the impact of Kae on cerebral infarction. We generated the middle cerebral artery occlusion (MCAO) mouse model to study the effects of Kae on infarction volume and neurological function. The oxygen and glucose deprivation (OGD)/reoxygenation (R) model of neural stem cells (NSCs) was established to study the effects of Kae on cell viability, migration, and apoptosis. Cell processes were assessed by cell counting kit-8, Transwell assay, flow cytometry, and TUNEL analysis. The molecular mechanism was assessed using the Western blot. The results indicated that Kae attenuated MCAO-induced cerebral infarction and neurological injury. Besides, Kae promoted cell viability and migration and inhibited apoptosis of OGD/R-treated NSCs. Moreover, OGD/R suppressed total O‐GlcNAcylation level and O‐GlcNAcylation of β-catenin, thereby suppressing the Wnt/β-catenin pathway, whereas Kae reversed the suppression. Inactivation of the Wnt/β-catenin pathway abrogated the biological functions of NSCs mediated by Kae. In conclusion, Kae suppressed cerebral infarction by facilitating NSC viability, migration, and inhibiting apoptosis. Mechanically, Kae promoted O‐GlcNAcylation of β-catenin to activate the Wnt/β-catenin pathway. Kae may have a lessening effect on ischemic stroke.
Collaborative optimization algorithm for electric vehicle industry chain based on regional economic development needs
Authors: Lu Man , Sun Jianfei 
Published: March 2024

Abstract
With the development of the economy, many regions have experienced a slowdown in economic growth. In order to promote the development of the electric vehicle (EV) industry, the country has also begun to introduce various policies to encourage the development of the EV industry. In this context, many local governments have begun to introduce policies and measures related to the development of the EV industry, such as increasing land use for the development of the EV industry and increasing support for the new energy automobile industry. These policy measures have played a positive role in promoting the development of the EV industry, but there are also some problems. For example, when many local governments introduce policies to support the development of the new energy automobile industry, their support for the EV industry is not significant. This article studied the collaborative optimization of the EV industry chain in response to issues such as insufficient technical strength, imbalanced supply-demand relationship, and insufficient downstream service chain capabilities in the EV industry chain. This article analyzed the composition of the EV industry chain and established an EV industry chain model to address these issues. This article used collaborative optimization algorithms to analyze the production volume of EVs in the EV industry chain, as well as the comprehensive efficiency, pure technical efficiency, and scale efficiency values of upstream, midstream, and downstream. Through experimental analysis, it was found that the comprehensive efficiency value of the upstream of the EV industry chain after using the collaborative optimization algorithm was 0.0792 higher than before. The research results of this article have provided reference significance for the analysis of collaborative optimization algorithms in other fields.
Effect of temperature on oxidation during boriding of Ni-Hard 4
Authors: Aydoğmuş Tuna 
Published: March 2024

Abstract
Ni-Hard 4, also known as white cast iron, is widely used in many applications that demand high mechanical strength. This material is recognized for its ability to withstand challenging conditions. In this study, surface modification processes, particularly boriding, were carried out on the material. Boriding is considered an effective process for enhancing the mechanical strength of a surface. While there are various methods for performing boriding, the pack-boriding method was chosen for this study. This method was applied in a typical heat treatment furnace. Ni-Hard 4 specimens were subjected to different combinations of temperature (1000–1200 °C) and 4 h duration, resulting in a total of three distinct samples. Subsequently, the microstructure, hardness, and chemical composition of the boride layers formed on the material’s surface were meticulously examined. As a result of the detailed analysis, it was determined that if the boriding process was carried out in a furnace without controlled atmosphere, high temperature oxidation started on the surface of Ni-Hard 4, and in this case it increased in parallel with the increase in temperature.
The crystal structure of t-butyl 7-[3-(4-fluorophenyl)-1-(propan-2-yl)-1H-indol-2-yl]-3,5-dihydroxyhept-6-enoate, C28H34FNO4
Authors: Alex Vergiro Tchuente Fofeu , Xie Tai-Yang , Zou Jing , Xu Xin-Xin , Xu Rou-Han , Jiang Cheng-Jun 
Published: March 2024

Abstract
C28H34FNO4, monoclinic, C2/c (no. 15), a = 21.7795(12) Å, b = 5.9103(4) Å, c = 39.830(2) Å, β = 100.866(3)°, V = 5035.1(5) Å3, Z = 8, R
gt(F) = 0.0487, wR
ref(F
2) = 0.1376, T = 170 K.
Evaluation of magnetic and electrochemical performance of copper oxide nanoparticles using Myristica fragrans (mace) extract
Authors: Murugan Shandhiya , Balraj Deepika , Amirtharajan Saranya , Manimuthu Ramesh P , N Venkata Rama R , Balasundaram Janarthanan , Ziaudeen Mohamed R , Saminathan Sharmila 
Published: March 2024

Abstract
The synthesis of metal oxide nanoparticles using natural extract encourages the futuristic design of an environmentally friendly system by getting rid of the dangerous, toxic substances. The food industry in India is paying a lot of attention to Myristica fragrans, often known as mace, due to its rich medicinal significance. In the current study, M. fragrans (Mace) aqueous extract was used to prepare copper oxide (CuO) nanoparticles. Phytochemical screening confirms the presence of bioactive substances such as alkaloids, sterols, glycosides, and flavonoids in the extract. XRD and SEM measurements show that the nanoparticles have a monoclinic structure with polyhedral shape. Using the Debye-Scherrer formula, the material’s average crystallite size was found to be 85 nm. Based on the Tauc plot, an optical band gap of the prepared CuO NPs was calculated as 2.6 eV. At room temperature, the material’s magnetic property was investigated using VSM analysis. Congo red was used to examine the photocatalytic properties of the materials with various timings. CuO nanoparticles’ antibacterial activity was evaluated at various doses against Staphylococcus aureus and Klebsiella pneumoniae. Almost, CuO NPs exhibit better response against both the bacteria. Moreover, research investigations using cyclic voltammetry was carried out to assess the produced nanoparticles’ pseudocapacitive qualities. At a scan rate of 10 mV s−1, the material produced a good specific capacitance of 233.8 F/g with 1 M of KOH as an electrolyte.
Lean Photovoltaik
Authors: Kern Ferdinand , Mielke Tim , Biernath Helge 
Published: March 2024

Abstract
The expansion of renewable energies poses a significant challenge worldwide. Numerous national and international agreements and laws promote and demand a much stronger expansion than before. A significant contribution is expected from the increased use of photovoltaics (PV). Large scale solar power plants cover vast areas and consist of hundreds of thousands of modules. With increasing quantities, the potential to make installation more efficient using factory operation methods also increases. However, established approaches such as Lean Production Systems (LPS) cannot be transferred from the factory to the PV construction site without adaptations, due to the different preconditions. In a previous article, the challenges in the installation of PV power plants and the potential for the implementation of LPS have been analysed based on a study of the current state of production efficiency. For this purpose, solar projects by Sunstall Inc., USA, were accompanied. In this article, the implementation and the results of an experimental application of LPS on these solar projects are presented.
Einsparpotenzial alternativer Trocknungstechnologien
Authors: Magin Jonathan , Elserafi Ghada , von Hayn Adrian , Stellmacher Katrin , Weigold Matthias 
Published: March 2024

Abstract
The importance of parts cleaning and drying in the metal cutting industry is increasing due to higher quality requirements. At the same time, rising energy prices and climate policy goals create increasing incentives to reduce energy consumption. This study quantifies savings potentials in the use of infrared radiators and inductors in industrial parts drying. The performed experiments illustrate that alternative drying technologies enable a reduction in energy consumption up to 65 %.
Handlungsstufenplan für Digitalisierungsprojekte in der Produktion
Authors: Beckschulte Sebastian , Huebser Louis , Schulze Tobias , Schmitt Robert H. 
Published: March 2024

Abstract
In a rapidly evolving production landscape, digitalization projects are gaining increasing importance. An action level plan is a versatile tool and offers a structured framework for successfully implementing digitalization projects in production. A practical example from the automotive industry is used to analyze challenges, opportunities and key findings that can support manufacturing companies in the successful implementation of digitalization projects.
Quantenalgorithmen zur Optimierung von Produktions- und Logistikprozessen
Authors: Klug Florian 
Published: March 2024

Abstract
Quantum computing is an important building block for the digitalized future of a company. Successes in recent years – in the development, construction and operation of quantum computers – have led to the achievement of a preliminary stage of industrialization. Quantum-based algorithms have the potential to solve operational decision-making problems more quickly and thus to manage complex decision-making situations dynamically. German industrial companies can already demonstrate the first concrete use cases for quantum algorithms to optimize factory processes.
Eine Referenzarchitektur für das Industrial Metaverse
Authors: Ullrich Marco , Heller Jonas , Knüpper Jonas , Lüdemann-Ravit Bernd 
Published: March 2024

Abstract
Das Industrial Metaverse scheint der nächste große Game Changer in der modernen Industrie zu werden und wird diese signifikant verändern. Die Vision ist nicht nur die Simulation einer einzelnen Anlage, wie sie Unternehmen heute beispielsweise bei der virtuellen Inbetriebnahme einsetzen, sondern ganzheitlicher Anlagenverbunde aus heterogenen Maschinen samt Fabrikperipherie und Infrastruktur – einer Digitalen Fabrik. Um das Industrial Metaverse zum Leben zu erwecken, wird eine Vielzahl zusätzlicher Technologien und Innovationen benötigt, als lediglich Digitale Zwillinge. Dieser Beitrag schlägt eine ganzheitliche Referenzarchitektur eines Industrial Metaverse vor und fokussiert auf dessen Nutzen.
The Inflation Reduction Act as an Element of Shaping the US Grand Strategy and the UN Strategy of Global Goals
Authors: Lizak Robert , Skuza Sebastian 
Published: March 2024

Abstract
The purpose of this article is to present the US Inflation Reduction Act (IRA), signed by the US president on 16 August 2022, which provides the legal basis for the largest nationwide public investment in the economic, social and environmental spheres since the 1930s. The Act is an offshoot of the 2020–2021 legislative effort known as the Build Back Better Plan, which aims to create synergies between the US Grand Strategy to maintain the ‘exorbitant privilege’ of being the economic hegemon (resulting from the balance of power in the global economy and international politics, the status of the US dollar as an international currency and the oversight of the global reserve currency that has protected US sovereignty, security and prosperity to date) and the Agenda 2030 for Sustainable Development, adopted in 2015 by 193 UN Member States. The assessment of the US IRA is relevant not only because of the attempt made to holistically assess US strategic policy goals, including in the area of sustainable finance, but also to isolate global development trends in economic, social and environmental areas.
EU Regulation of the Crypto-Assets Market
Authors: Hrabčák Ladislav , Štrkolec Miroslav 
Published: March 2024

Abstract
The present paper discusses the issue of regulation of the crypto-assets market. This area is still struggling with a lack of legislation, and there are only some initiatives to regulate the market. The aim of the article is to analyse the state of legal regulation of the crypto-assets market while simultaneously pointing out problematic issues with de lege ferenda proposals. For this purpose, we established two hypotheses: the crypto-assets market needs to be regulated by legal acts of a European nature (H1), and the adopted EU legal acts regulating the crypto-assets market are adequate and sufficient (H2). Several types of scientific papers, such as analysis, synthesis, and the historical method, were used in the preparation of this paper.
Tax Instalment Plans: A Legal Instrument of Financial Sustainability in a Crisis
Authors: Svobodová Tereza 
Published: March 2024

Abstract
The Covid-19 pandemic as well as the war in Ukraine represent the biggest hit to the Czech economy since the Great Recession. In the Czech Republic, several tax measures are being used to help economic entities overcome the current crisis and keep their businesses running. One of them is the tax instalment plan. This article aims to identify why the tax instalment plan could be an appropriate fiscal measure in times of economic crisis. The author presents a classical legal instrument in the tax area – the tax instalment plan – and analyses it from an innovative point of view rather than the usual perspective, that is, from the macroeconomic point of view. The article analyses the legal conditions for the use of this instrument in the Czech Republic, points out the difficulties of interpretation in practice and evaluates it in the context of the theoretical background of desirable fiscal crisis measures. The conclusions of the research confirm the hypothesis that this legal instrument is an effective and used tool for facilitating the sustainability of private and public finances in times of crisis. It combines the desirable aspects of both automatic stabilisers and discretionary measures.
Towards the Greening of Banking: A Comparison of the Polish and Czech Financial Markets
Authors: Jurkowska-Zeidler Anna , Schweigl Johan 
Published: March 2024

Abstract
The role of the banking system in promoting and implementing the Sustainable Development Goals in Europe has recently become very significant. As an important part of the financial sector, green banking helps to achieve the goals of sustainable development, which, in times of global financial, economic, climate, and social crises and of war, is very important. The authors aim to present the general approach to ‘green banking’ in Poland and the Czech Republic as represented by the banking sectors themselves and the national regulatory and supervisory authorities, with reference to the EU legal framework. They posit that ‘green banking’ is an increasingly important trend in the development of the Polish and Czech financial markets and conclude that EU regulations are the biggest driver of change in green finance, resulting in an increased awareness of environmental, social, and corporate governance (ESG) factors. What is required, however, is greater systemic involvement of the institutions that constitute the financial safety net, especially central banks. The research has used a theoretical and dogmatic-legal method, based on content analysis and the availability of source information, i.e. theoretical-legal publications, overview sector reports, and, in particular, legal regulations key to the topic.
Constitutional and Legal Regulations on Financial Security and the Security of the Financial Interest of the State in Regard to the Challenges of the 21st Century
Authors: Feret Elżbieta 
Published: March 2024

Abstract
This study demonstrates the interdependence of constitutional regulations and two types of state financial security: general financial security and the security of the financial interest of the state. An indication of these two types is possible due to existing legal regulations resulting primarily from constitutional regulations, but also from ordinary laws that allow for the analysis of the activities of public authorities in the field of collecting and spending public funds, in the budgetary, tax and banking contexts. The considerations discussed here are of particular importance due to the unstable political, economic, social and, above all, financial situation. In such difficult circumstances, it seems obvious that constitutional regulations should be the basis for ensuring the financial security of the state, while indicating to what extent the applicable provisions meet the challenges of the modern, unstable world. The considerations have been based primarily on the regulations resulting from the Constitution of the Republic of Poland, with an indication of which are the most important from the point of view of the adopted topic, the regulation of separate acts. In order to discuss the selected issues, it has also been necessary to refer to selected bibliographic items and court decisions. The study is selective and not comprehensive, constituting a stimulus for further research in this area.
Típus-lakóépületek Magyarországon
Authors: Mándoki Réka 
Published: March 2024

Az elmúlt ötven év során sok iparágban, például a ruha- és a bútoriparban, az egyedileg tervezett és gyártott, kisszériás áruk helyét egyre inkább a sorozatgyártott tömegtermékek vették át a fejlett országokban. Mivel a sorozatgyártás lehetőséget biztosít a termékek optimalizálására, azok sok esetben olcsóbbak és kiszámíthatóbb minőségűek lehetnek, mint az egyedi termékek. Ez pedig egy megfelelően széles választék fenntartása mellett kifejezetten vonzó a vásárlók többsége számára.Bár az építőipar más iparágakhoz képest lassan fejlődik, az épületelemek előregyártása egyre jellemzőbbé válik Európában a szakképzett munkaerő hiánya és a helyszíni kivitelezés kockázatai miatt. Egyelőre ugyan a legtöbb épület még egyedi tervek alapján születik, de az előregyártás terjedésével, a nagy fejlesztő cégek térnyerésével és a lakáspiac drágulásával kérdéses, hogy a lakóépületek meddig lesznek képesek megőrizni az egyediségüket vagy egy hasonló folyamatnak leszünk hamarosan a szemtanúi, mint ami a ruha- és a bútoriparban lejátszódott.Mivel az épített környezettől elvárt egyediség összefügg az ember megélt tapasztalataival, a felvázolt jelenség apropóján a jelen cikk azt vizsgálja, hogy Magyarországon milyen motivációk álltak a formai szempontból egynemű lakókörnyezetek létrejöttének hátterében. A példák felsorolása mellett a cikk felvázol egy keretrendszert, amin belül értelmezhetővé válnak azok a társadalmi folyamatok, amik megmagyarázzák, hogy miért és miként építünk típusépületeket. A javasolt rendszerezés szempontként vonja be a típusépületek elemzésébe, hogy ezek az épületek fentről lefelé vagy alulról felfelé építkező folyamat eredményei-e, elterjedésük projektspecifikus-e, és hogy maguk az épületelemek szabványosítottak-e.A jelen cikk a körülöttünk lezajló folyamatok értelmezésén felül egyfelől bemutat példákat arra, amikor a típusépületek használatával harmonikus épített környezet jön létre, másfelől pedig bemutatja azt is, hogy milyen okok állhatnak amögött, amikor a típusépületek nem válnak be. Mindez segíthet abban, hogy elkerüljük a jövőben az olyan épületek sorozatgyártását, amelyek borítékolhatóan nem lesznek képesek hosszú távon is megőrizni társadalmi elfogadottságukat.
INFESTASI EKTOPARASIT Dactylogyrus sp DI SUNGAI KELEKAR, INDRALAYA, SUMATERA SELATAN
Authors: Dwinanti Sefti Heza , Septarisa Geza Intan , Tanbiyaskur Tanbiyaskur , Amin Muhammad , Rarassari Madyasta Anggana 
Published: March 2024

Parasit Dactylogyrus sp. merupakan ektoparasit yang dapat ditemukan baik pada ikan budidaya ataupun ikan yang hidup di perairan umum seperti sungai. Informasi keberadaan parasit di perairan umum dapat dijadikan indikator lingkungan dan pertimbangan penggunaan sumber air untuk budidaya ikan. Penelitian ini bertujuan untuk mengetahui penyebaran parasit Dactylogyrus sp. pada ikan yang berasal dari Sungai Kelekar di Kabupaten Ogan Ilir, Sumatera Selatan, Indonesia. Sampel ikan diambil pada bulan Juni hingga Agustus 2020 di tiga desa yang dilintasi oleh Sungai Kelekar yaitu Desa Tanjung Baru, Desa Burai dan Desa Sakatiga. Jumlah ikan yang diperiksa sebanyak 374 ekor yang terdiri dari 14 spesies. Data yang diperoleh dianalisis menggunakan R dengan “package bipartite” dan boxplot yang disajikan dalam bentuk gambar dan tabel. Selain Dactylogyrus sp.,, ektoparasit lain yang ditemukan adalah Argulus sp. dan Cyclops sp. Kecenderungan infestasi organ adalah insang dengan nilai prevalensi sebesar 46,48% sedangkan nilai intensitas sebesar 9,2 individu..ikan-1. Secara keseluruhan infestasi Dactylogyrus sp. pada ikan yang berasal dari Sungai Kelekar memiliki frekuensi infeksi umum (commonly) dengan tingkat infestasi moderat (moderate).Dactylogyrus sp is an ectoparasite that can be found in both farmed fish and wild fish populations. Information on the presence of parasites in wild fish populations can be used as an environmental indicator and consideration of the use of water sources for fish farming. This study aimed to determine the spread of ectoparasite Dactylogyrus sp. in fish originating from the Kelekar River in Ogan lir Regency, South Sumatra, Indonesia. Fish samples were collected between June and August 2020 in three villages crossed by the Kelekar River, namely Tanjung Baru, Burai, and Salatiga villages. The number of fish examined was 374, consisting of 14 species, The data obtained were analyzed using R with the "bipartite package" and boxplot presented in figures and tables. Besides Dactylogyrus sp, other ectoparasites found were Argulus sp and Cyclops sp. The preferred infested organ by Dactylogyrus sp was in gills with a prevalence value of 46,48%, while the intensity value was 9.2 ind. fish, Overall, Dactylogyrus sp infestation in fish originating from the Kelekar River was categorized as a common infection with moderate intensity.
Interoperable communication for autonomous mobile robots
Authors: Zager Marvin , Worpenberg Christian , Sieber Christoph , Vieira da Silva Luis Miguel , Grebner Tobias , Fay Alexander 
Published: March 2024

The deployment of teams of autonomous mobile robots provides potential by leveraging the strengths of individual robots and compensating for their disadvantages. This makes them particularly well suited to carrying out complex scenarios for logistics, environmental monitoring or search and rescue. However, the success of such teams relies on achieving seamless interoperability among differing robots. In the area of the Internet of Robotic Things (IoRT), addressing this interoperability challenge becomes paramount. Therefore, an interoperable communication concept is introduced that considers interoperability based on semantic, syntactic, and technical clusters. It is designed to meet the specific requirements of multimodal autonomous mobile robots. Based on legal considerations, this method enables the integration and collaboration of different autonomous mobile robots in real-life applications. A logistics scenario involving multiple autonomous mobile robots illustrates the applicability of this interoperable communication concept.