bluuebunny/crossref_metadata_2025_split huggingface dataset:
Cementless Acetabular Reconstruction and Structural Bone-Grafting in Dysplastic Hips
Authors: Hendrich C. , Engelmaier F. , Mehling I. , Sauer U. , Kirschner S. , Martell J.M. 
Published: March 2007

BACKGROUND:
Studies of acetabular reconstruction with use of cement and bulk bone graft have demonstrated increasing rates of cup failure in patients with dysplastic hips seven years after total hip arthroplasty. Comparable data on the long-term results of bulk bone-grafting done in conjunction with cementless implants are limited. The aim of this study was to review the clinical and radiographic results of autologous bulk bone-grafting in conjunction with a cementless cup.
METHODS:
From 1987 to 1992, forty-seven patients (forty women and seven men, with an average age of 50.4 years) who had developmental dysplasia of the hip underwent fifty-six total hip arthroplasties and received a structural graft in combination with a cementless Harris-Galante type-I cup. All patients were followed prospectively. In fifty-five hips, implant migration was measured with single-image radiographic analysis.
RESULTS:
After an average duration (and standard deviation) of 10.2 ± 2.9 years, three patients (four hips) had died. In the surviving patients, four implants had been revised and two had radiographic evidence of loosening. With use of revision and loosening as end points, the eleven-year survival rates were 91.6% and 88.9%, respectively. Of the fifty implants that had no loosening, fourteen had measurable cup migration, thirty-five had no migration, and one implant could not be measured. All migrations but one were progressive. With loosening used as the end point, the survival rate at eleven years was 100% for the implants with no migration; however, the survival rate for the cups that had migrated was 69.3% (p = 0.0012).
CONCLUSIONS:
The eleven-year survival rate for the spherical press-fit cups in combination with bulk bone-grafting is satisfactory, given the complexity of these reconstructions. However, the difference between the survival of the implants that had migrated and those that had not was significant. We expect that the thirteen implants with progressive acetabular migration at the time of the latest follow-up are at risk for loosening, which will increase the revision rate for this series in the coming years.
Spatiotemporal Nonattainment Assessment of Surface Water Tetrachloroethylene in New Jersey
Authors: Akita Yasuyuki , Carter Gail , Serre Marc L. 
Published: March 2007

ABSTRACTTetrachloroethylene (PCE) is one of the most frequently detected volatile organic compounds (VOCs) in water systems across the USA. In New Jersey, the Department of Environmental Protection (NJDEP) monitors surface water quality at several sites throughout the state. However due to budget and scientific limitations, the sampling data is insufficient to assess all river streams in New Jersey. To address this problem, the objective of this study is to utilize a framework for the space/time estimation of PCE throughout all river reaches in New Jersey over the 1999 through 2003 time period and to track how this concentration evolves over time. We use the Bayesian maximum entropy (BME) mapping method to take into account the composite spatiotemporal variability of PCE, and we produce maps providing a stochastic description of the distribution of PCE at all times throughout the river network. In addition, we conduct a nonattainment assessment analysis by applying a criterion based on the estimated probability distribution function that allows us to identify the river miles that are highly likely in nonattainment of the standard, those that are highly likely in attainment of the standard, and the remaining labeled as nonassessed. Using this criterion we investigate how the river miles contaminated by PCE vary over space and time, and we identify watershed management areas (WMAs) with contamination problems. Finally, a cross validation comparison with a purely spatial analysis demonstrates that the space/time framework leads to a better estimation and a reduction of the number of nonassessed miles.
Tile Water Quality following Liquid Swine Manure Application into Standing Corn
Authors: Ball Coelho B. R. , Roy R. C. , Topp E. , Lapen D. R. 
Published: March 2007

ABSTRACTThe quality of water draining fields fertilized with liquid swine (Sus scrofa) manure (LSM) sidedressed into standing corn (Zea mays L.) at rates ranging from 0 to 94 m3 ha−1, either topdressed (TD) onto the surface, or injected (INJ) into the soil once annually for each of three consecutive years was evaluated. Liquid swine manure application rate was a critical driver of preferential flow of LSM to tile as detected by turbidity, concentrations of NH4+–N, dissolved reactive phosphorus (DRP), and the presence of enteric bacteria (Escherichia coli). Contaminant movement to drains occurred immediately after 75 and 94 m3 LSM ha−1 were injected (e.g., 2.5 mg DRP L−1, 3‐yr average). With injection of 56 m3 ha−1 or less, drainage water was not turbid and concentrations of NH4+–N, DRP, and enteric bacteria were dramatically lower than with the higher rates, even when tiles flowed freely during manure application. Application method also affected tile water quality. With TD applications (37 and 56 m3 ha−1), nutrients and bacteria did not move to tiles at the time of application, but with rains that fell within 3 d after application, concentrations increased (e.g., 0.1 mg DRP L−1), although less than with INJ. Overall, sidedress injection rates that supplied adequate crop nutrients did not compromise drainage water quality.
Effects of buprenorphine on nociception and spontaneous locomotor activity in horses
Authors: Carregaro Adriano B. , Luna Stelio P. L. , Mataqueiro Maria Isabel , de Queiroz-Neto Antonio 
Published: March 2007

Abstract
Objective—To investigate spontaneous locomotor activity (SLA) and antinociceptive effects of buprenorphine in horses.
Animals—6 healthy adult horses.
Procedures—Horses received each of 3 treatments (10 mL of saline [0.9% NaCl] solution, 5 μg of buprenorphine/kg, or 10 μg of buprenorphine/kg).Treatments were administered IV. Order of treatments was randomized, and there was a 10-day interval between subsequent treatments. Spontaneous locomotor activity was investigated in a behavioral box by use of infrared photoelectric sensors connected to a computer, which detected movement of each horse. Antinociceptive effect was investigated by hoof-withdrawal reflex latency (HWRL) and skin-twitching reflex latency (STRL) after painful stimulation with a heat lamp.
Results—Moderate excitement was observed in all horses from 5 to 10 minutes after the administration of both dosages of buprenorphine. The SLA increased significantly for 6 and 14 hours after IV administration of 5 and 10 μg of buprenorphine/kg, respectively. Values for HWRL increased significantly only at 30 minutes after injection of 5 μg of buprenorphine/kg, whereas STRL and HWRL each increased significantly from 1 to 6 hours (except at 2 and 4 hours) and 11 hours, respectively, after injection of 10 μg of buprenorphine/kg.
Conclusions and Clinical Relevance—IV injection of buprenorphine caused a dose-dependent increase in SLA, but only the dose of 10 μg/kg induced analgesia on the basis of results for the experimental method used.
Detection of Bartonella henselae DNA in two dogs with pyogranulomatous lymphadenitis
Authors: Morales Sofia C. , Breitschwerdt Edward B. , Washabau Robert J. , Matise Ilze , Maggi Ricardo G. , Duncan Ashlee W. 
Published: March 2007

Abstract
Case Description—1 dog evaluated because of inappetence and lameness of the left hind limb of 1 day's duration and 1 dog evaluated because of inappetence, fever, and lymphadenopathy of 2 weeks' duration.
Clinical Findings—Histologic examination of excisional biopsy specimens from lymph nodes revealed pyogranulomatous lymphadenitis in both dogs. Quantitative real-time PCR assays detected Bartonella henselae DNA in blood samples and affected lymph node specimens from both dogs. Antibodies against B henselae were not detected via immunofluorescent antibody testing during active disease in either dog.
Treatment and Outcome—1 dog recovered after 6 weeks of treatment with doxycycline (5 mg/kg [2.3 mg/lb], PO, q 12 h), whereas the other dog recovered after receiving a combination of azithromycin (14.5 mg/kg [6.6 mg/lb], PO, q 24 h for 21 days), doxycycline (17.3 mg/kg [7.9 mg/lb], PO, q 24 h for 4 weeks), and immunosuppressive corticosteroid (prednisone [3 mg/kg {1.4 mg/lb}, PO, q 24 h], tapered by decreasing the daily dose by 25% every 2 weeks) treatment.
Clinical Relevance—B henselae is implicated as a possible cause or a cofactor in the development of pyogranulomatous lymphadenitis in dogs. In dogs with pyogranulomatous lymphadenitis, immunofluorescent assays may not detect antibodies against B henselae. Molecular testing, including PCR assay of affected tissues, may provide an alternative diagnostic method for detection of B henselae DNA in pyogranulomatous lymph nodes.
Antioxidant supplementation influences the neutrophil tocopherol associated protein expression, but not the inflammatory response to exercise
Authors: Sureda Antoni , Tauler Pedro , Aguiló Antoni , Cases Nuria , Llompart Isabel , Tur Josep , Pons Antoni 
Published: March 2007

Abstract
Intense exercise induces inflammatory-like changes and oxidative stress in immune cells. Our aim was to study the effects of antioxidant diet supplementation on the neutrophil inflammatory response and on the tocopherol associated protein (TAP) expression after exhaustive exercise. Fourteen male-trained amateur runners were randomly divided in two placebo and supplemented groups. Vitamins C (152 mg/d) and E (50 mg/d) supplementation were administrated to the athletes for a month, using an almond based isotonic and energetic beverage. Non-enriched beverage was given to the placebo group. After one month, the subjects participated in a half-marathon race (21 km-run). Neutrophil TAP mRNA expression and markers of the inflammatory response were determined before, immediately after, and 3 h after finishing the half-marathon race. TAP expression increased after exercise mainly in the neutrophils of the placebo group. Exercise induced an inflammatory response in both placebo and supplemented groups, manifested with neutrophilia, increased creatine kinase and lactate dehydrogenase serum activities, neutrophil luminol chemiluminescence and myeloperoxidase release. Plasma malondialdehyde only increased in the placebo group after exercise. Diet supplementation with moderate levels of antioxidant vitamins avoids plasma damage in response to exhaustive exercise without the effects on the inflammatory process. Neutrophil degranulation and increased tocopherol associated protein could contribute to the neutrophil protection from the oxidative stress.
Rotating fluidized beds in a static geometry: Experimental proof of concept
Authors: De Wilde Juray , de Broqueville Axel 
Published: March 2007

AbstractThe new concept of a rotating fluidized bed in a static geometry (RFB‐SG) is presented. The rotating motion of the particle bed and the tangential fluidization of the solids are obtained by the tangential injection of the fluidization gas via multiple gas inlet slots in the outer cylindrical wall of the fluidization chamber. The solids experience a radially outwards centrifugal force. The gas, on the other hand, is forced to move radially inwards towards a chimney with one or more outlet slots, creating a radially inwards gas‐solid drag force and fluidizing the solids radially. The new fluidization concept is experimentally investigated and proven using one and the same non‐optimized fluidization chamber design with either large diameter, low density polymer particles or small diameter, higher density Alumina particles. The fluidization chamber is operated in continuous mode, at different solids loadings and in the vertical and horizontal position. © 2007 American Institute of Chemical Engineers AIChE J, 2007
Malignant proliferating pilar tumors arising in KID syndrome: A report of two patients
Authors: Nyquist Gurston G. , Mumm Christina , Grau Renee , Crowson A. Neil , Shurman Daniel L. , Benedetto Paul , Allen Pamela , Lovelace Kelli , Smith David W. , Frieden Ilona , Hybarger C. Patrick , Richard Gabriele 
Published: March 2007

AbstractWe report on two young adults with KID syndrome and follicular hyperkeratosis, hidradenitis suppurativa of the groin, progressive development of proliferative pilar cysts and dissecting cellulitis of the scalp, who developed metastatic malignant pilar tumors. Based on our findings, we believe that cancer surveillance in patients with KID syndrome should include screening for pilar tumors and their early removal to avoid development of malignant proliferating pilar tumors with poor prognosis. © 2007 Wiley‐Liss, Inc.
Duplication of 17(p11.2p11.2) in a male child with autism and severe language delay
Authors: Nakamine Alisa , Ouchanov Leonid , Jiménez Patricia , Manghi Elina R. , Esquivel Marcela , Monge Silvia , Fallas Marietha , Burton Barbara K. , Szomju Barbara , Elsea Sarah H. , Marshall Christian R. , Scherer Stephen W. , McInnes L. Alison 
Published: March 2007

AbstractDuplications of 17(p11.2p11.2) have been associated with various behavioral manifestations including attention deficits, obsessive‐compulsive symptoms, autistic traits, and language delay. We are conducting a genetic study of autism and are screening all cases for submicroscopic chromosomal abnormalities, in addition to standard karyotyping, and fragile X testing. Using array‐based comparative genomic hybridization analysis of data from the Affymetrix GeneChip® Human Mapping Array set, we detected a duplication of ∼3.3 Mb on chromosome 17p11.2 in a male child with autism and severe expressive language delay. The duplication was confirmed by measuring the copy number of genomic DNA using quantitative polymerase chain reaction. Gene expression analyses revealed increased expression of three candidate genes for the Smith–Magenis neurobehavioral phenotype, RAI1, DRG2, and RASD1, in transformed lymphocytes from Case 81A, suggesting gene dosage effects. Our results add to a growing body of evidence suggesting that duplications of 17(p11.2p11.2) result in language delay as well as autism and related phenotypes. As Smith–Magenis syndrome is also associated with language delay, a gene involved in acquisition of language may lie within this interval. Whether a parent of origin effect, gender of the case, the presence of allelic variation, or changes in expression of genes outside the breakpoints influence the resultant phenotype remains to be determined. © 2007 Wiley‐Liss, Inc.
Serotonergic influences on life‐history outcomes in free‐ranging male rhesus macaques
Authors: Howell Sue , Westergaard Greg , Hoos Beth , Chavanne Tara J. , Shoaf Susan E. , Cleveland Allison , Snoy Philip J. , Suomi Stephen J. , Dee Higley J. 
Published: March 2007

AbstractSeveral studies have demonstrated that nonhuman primate males with low cerebrospinal fluid (CSF) levels of the serotonin metabolite 5‐hydroxyindoleacetic acid (5‐HIAA) exhibit antisocial behavior patterns. Included in these deleterious patterns are impulse control deficits associated with violence and premature death. No studies to date have longitudinally studied the long‐term outcome of young subjects with low CSF 5‐HIAA concentrations as they mature into adults. In this study we examined longitudinal relations among serotonergic and dopaminergic functioning, as reflected in CSF metabolite concentrations, aggression, age at emigration, dominance rank, and mortality in free‐ranging rhesus macaque (Macaca mulatta) males. Our results indicate long‐term consistency of individual differences in levels of 5‐HIAA in CSF in the subject population from the juvenile period of development through adulthood. We found a significant negative correlation between 5‐HIAA concentrations measured in juveniles and rates of high‐intensity aggression in the same animals as adults. Further, CSF 5‐HIAA concentrations were lower in juveniles that died than in animals that survived. For the young animals that migrated there was a positive correlation between CSF 5‐HIAA concentration and age at emigration, whereas for the animals that remained in their troop until later in sexual maturity there was a negative correlation between CSF 5‐HIAA concentration and age of emigration. After animals emigrated to a new troop, social dominance rank in the new troop was positively correlated with early family social dominance rank, but inversely correlated with juvenile CSF 5‐HIAA concentrations. Taken together, our findings suggest that males with low central serotonin levels early in life delay migration and show high levels of violence and premature death, but the males that survive achieve high rank. These findings indicate that longitudinal measures of serotonergic and dopaminergic functioning are predictive of major life‐history outcomes in nonhuman primate males. Low concentrations of CSF 5‐HIAA are associated with negative life‐history patterns characterized by social instability and excessive aggression, and positive life‐history patterns characterized by higher dominance rank. Am. J. Primatol. 69:851–865, 2007. © 2007 Wiley‐Liss, Inc.
Grooming relationships between breeding females and adult group members in cooperatively breeding moustached tamarins (Saguinus mystax)
Authors: Löttker Petra , Huck Maren , Zinner Dietmar P. , Heymann Eckhard W. 
Published: March 2007

AbstractGrooming is the most common form of affiliative behavior in primates that apart from hygienic and hedonistic benefits offers important social benefits for the performing individuals. This study examined grooming behavior in a cooperatively breeding primate species, characterized by single female breeding per group, polyandrous matings, dizygotic twinning, delayed offspring dispersal, and intensive helping behavior. In this system, breeding females profit from the presence of helpers but also helpers profit from staying in a group and assisting in infant care due to the accumulation of direct and indirect fitness benefits. We examined grooming relationships of breeding females with three classes of partners (breeding males, potentially breeding males, (sub)adult non‐breeding offspring) during three reproductive phases (post‐partum ovarian inactivity, ovarian activity, pregnancy) in two groups of wild moustached tamarins (Saguinus mystax). We investigated whether grooming can be used to regulate group size by either “pay‐for‐help” or “pay‐to‐stay” mechanisms. Grooming of breeding females with breeding males and non‐breeding offspring was more intense and more balanced than with potentially breeding males, and most grooming occurred during the breeding females' pregnancies. Grooming was skewed toward more investment by the breeding females with breeding males during the phases of ovarian activity, and with potentially breeding males during pregnancies. Our results suggest that grooming might be a mechanism used by female moustached tamarins to induce mate association with the breeding male, and to induce certain individuals to stay in the group and help with infant care. Am. J. Primatol. 69:1159–1172, 2007.© 2007 Wiley‐Liss, Inc.
Extra‐large cluster formation by Japanese macaques (Macaca fuscata) on Shodoshima Island, central Japan, and related factors
Authors: Zhang Peng , Watanabe Kunio 
Published: March 2007

AbstractJapanese macaques on Shodoshima Island habitually form very large rest clusters, in which 50+ or even 100+ individuals huddle together. This behavior is not seen in any other populations of the species. Mean cluster sizes of two groups of Shodoshima monkeys are three and four in summer and 17 and 16 in winter, respectively. A maximum of 137 individuals have been seen to huddle in one cluster. It is difficult to explain the extra large clusters on Shodoshima only as an adaptive behavior against cold, since Shodoshima is relatively warm in the range of habitats for Japanese macaques. Compared with other groups of Japanese macaques, Shodoshima monkeys show: more frequent affinitive interactions, shorter inter‐individual distance, more frequent ignoring of exclusion, more frequent aggression, less intense aggression, and more frequent counter‐aggression. These characteristics suggest that the Japanese macaques on Shodoshima have relaxed dominant relations. The specific social organization of Shodoshima monkeys may sustain the formation of extra large clusters. Inter‐group comparisons suggest that the social structure of Japanese macaques might be highly plastic, and that Shodoshima monkeys have less despotic, more tolerant social relations than typically reported for this species. Am. J. Primatol. 69:1119–1130, 2007. © 2007 Wiley‐Liss, Inc.
In vivo bone strain and bone functional adaptation
Authors: Demes Brigitte 
Published: March 2007

AbstractMechanistic interpretations of bone cross‐sectional shapes are based on the paradigm of shape optimization such that bone offers maximum mechanical resistance with a minimum of material. Recent in vivo strain studies (Demes et al., Am J Phys Anthropol 106 (1998) 87–100, Am J Phys Anthropol 116 (2001) 257–265; Lieberman et al., Am J Phys Anthropol 123 (2004) 156–171) have questioned these interpretations by demonstrating that long bones diaphyses are not necessarily bent in planes in which they offer maximum resistance to bending. Potential limitations of these in vivo studies have been pointed out by Ruff et al. (Am J Phys Anthropol 129 (2006) 484–498). It is demonstrated here that two loading scenarios, asymmetric bending and buckling, would indeed not lead to correct predictions of loads from strain. It is also shown that buckling is of limited relevance for many primate long bones. This challenges a widely held view that circular bone cross sections make loading directions unpredictable for bones which is based on a buckling load model. Asymmetric bending is a potentially confounding factor for bones with directional differences in principal area moments (Imax > Imin). Mathematical corrections are available and should be applied to determine the bending axis in such cases. It is concluded that loads can be reliably extrapolated from strains. More strain studies are needed to improve our understanding of the relationships between activities, bone loading regimes associated with them, and the cross‐sectional geometry of bones. Am J Phys Anthropol, 2007. © 2007 Wiley‐Liss, Inc.
Generalized electrostatic model of the wrapping of DNA around oppositely charged proteins
Authors: Arcesi Luca , Penna Giovanni La , Perico Angelo 
Published: March 2007

AbstractHistonelike proteins in prokaryotes and histone octamers in eukaryotes carry large positive charges, which are responsible of strong electrostatic interactions with DNA. As a result, DNA wraps around proteins and genetic information is condensed. We describe a generalized model of these electrostatic interactions mediated by salt that explains the wrapping of DNA around the nucleosome octamer, around remodeling factors in eukaryotes and around histonelike proteins in prokaryotes. It comes out that small changes in protein dimension and charge produce large effects in the supramolecular DNA–protein architecture. © 2007 Wiley Periodicals, Inc. Biopolymers 86: 127–135, 2007.This article was originally published online as an accepted preprint. The “Published Online” date corresponds to the preprint version. You can request a copy of the preprint by emailing the Biopolymers editorial office at biopolymers@wiley.com