bluuebunny/crossref_metadata_2025_split huggingface dataset:
Inconsistencies and Challenges around 'Secularism' in Nepal
Authors: Pant Dila Datt 
Published: February 2024

Although Nepal adopted secularism in 2015 as its official state-religion relationship, there are still several inconsistencies and challenges around it including that of freedom of religion or belief. Instead of adopting a gradual marginalization and privatization of religion as per the normative proposition of the secularism, Nepal continues to do the opposite or at times, make a fundamental departure from the notion of secular identity. The preservation and the reaffirmation of presence of religion in public sphere and preferential treatment to Hindu religion at the cost of others continues to create discrimination and pose challenges to implement secularism. These problems do not only seem to remain just non-congruent inconsistencies with the secular identity of the state at the theoretical level alone, but also seem to hinder inter-religious tolerance in practical terms such as right to freely profess, practice and preach religion, thereby impacting the lives of the religious minorities. Against this backdrop, this article examines the key legal-constitutional inconsistencies including state's practices, antagonistic socio-political narratives, and emerging challenges vis-à-vis secularism in Nepal.
Impact of Per Capita Health Expenditure on Child Health Outcomes in Nepal
Authors: Paudel Manisha 
Published: February 2024

This paper explores the relationship between child health outcomes and per capita health investment in Nepal, using key indicators such as child mortality rate, stunting, skilled birth attendance, and appropriate treatment for acute respiratory infections. The study utilizes the data primarily from the World Bank and the Ministry of Finance in Nepal. The study adopts quantitative analysis techniques, including correlation and regression analysis, to assess the impact of health investment on child health outcomes. The results show that increased per capita health expenditure is positively correlated with improved child health outcomes which shows linear growth in different variables if compared with the per capita investment done in health. There is a negative correlation between per capita health expenditure and child mortality under 5 years of age and this is evidenced that increased per capita health expenditure reduces the child mortality among under 5 years of children. Thus, the study aims to highlight the importance of allocating resources in policy reforms, capacity building and allocating resources in the health sector. The study also incorporates relevant resources from scholarly articles and academic literature to provide a comprehensive understanding of the topic and support the analysis regarding the relationship between per capita health investment and child health outcomes.
Жоғары мектепте ұлттық әдебиетті зерттеу мен оқытудың әдіснамалық мәселелері
Authors: Жарылғапов Ж.Ж 
Published: February 2024

Мақалада жоғары оқу орындарында қазіргі таңдағы ұлттық әдебиетті зерттеу мен оқытудың әдіснамалық мәселелері қарастырылған. Кеңестік дәуірден келе жатқан, бүгінгі талаптарға жауап бере алмайтын ғылыми-әдіснамалық, оқу-әдістемелік концепциялар анықталған. Қазақстанның Тәуелсіздік алуымен бірге ұлттық құндылықтарға, оның ішінде әдеби мұраларға, оны игеру мен оқытуда жаңаша көзқарастар қалыптастыру — педагогика мен әдебиеттану ғылымының бірлесе шешетін маңызды мәселелерінің бірі. Жаһандану процесінің шапшаң жүруі өз талаптарын қойып отыр. Автор қазақ әдебиетін әлемдік әдебиет контексінде зерттеудің өзекті мәселелерін көрсете отырып, оны шешудің жолдарын ұсынған. Әлемдік құбылыстар мен ұлттық әдебиеттер арасындағы ортақ тенденцияларды айқындауда түрлі ғылыми мектептердің қалыптастырған әдістемелеріне, пәнаралық байланыстардың маңызына талдаулар жасалған.
К проблеме определения стратегий при прямом и опосредованном переводе
Authors: Альжанова А.Ы. , Мажитаева Ш. , Балмагамбетова Ж.T. 
Published: February 2024

Статья посвящена исследованию переводческих стратегий межъязыковой адаптации на материале трилогии А. Нурпеисова «Қан мен тер». Целью статьи является осуществление сравнительносопоставительного анализа оригинала с прямым переводом на русский и опосредованным переводом на английский. Основное внимание в работе акцентировано на рассмотрении способов реализации стратегий в транслятах путем использования переводческих трансформаций. Авторами предпринята попытка выяснить адекватность передачи специфики индивидуального стиля автора оригинала впереводных текстах, уровень межъязыкового соответствия переводов исходному тексту, степень равноценности регулятивного воздействия переводного текста оригиналу. Анализ исследуемого вопроса доказывает несостоятельность опосредованного перевода в силу значительных потерь в плане содержания и выражения. Результаты исследования будут интересны специалистам в области лингвистики, переводоведения.
Integrating Virtual Tools Into the Face-To-Face Teaching of Undergraduate Analytical Chemistry
Authors: Pighín Andrés Fabián , Rigacci Laura Natalia , Camilli Emiliano , Chirillano Ana Clara , Cufré Juan Ángel , Villanueva Maria Emilia 
Published: February 2024

At the National University of Luján, traditional classroom-based instruction characterized the analytical chemistry courses. However, in response to evolving educational needs, a transition to hybrid education combining virtual and face-to-face activities is occurring. In this context, some questions arise: Can all face-to-face activities be replaced by virtual activities? What benefits does the inclusion of virtual activities bring to the curriculum?

Reflecting on the experiences gained during the virtual instruction period that occurred due to the pandemic, the teaching group recognized the value of integrating virtual and face-to-face components. In a comparative assessment of teaching tools, the consensus emerged that a blended approach is crucial for effective analytical chemistry education in the current educational landscape.

The findings indicated that, for theoretical lessons, a hybrid approach with face-to-face sessions complemented by asynchronous virtual tools proved to be advantageous. This allowed students the flexibility to review lessons at their convenience. Regarding practical work, a preference for face-to-face instruction was noted, as it facilitated hands-on experience in laboratories with real equipment and samples. However, it was found that the simulation software for gas and liquid chromatography equipment allowed the incorporation of valuable experiences for the study of both methodologies without extending the time required to carry out the practical work or requiring new inputs.
Authors: Mutia Mutia , Nursal Dien Gusta Anggraini , Yuni Hamidatul , Syafrawati Syafrawati 
Published: February 2024

Background: Smoking is a health problem in Indonesia with a high level of use. Data from Riskesdas (2018) in Padang City shows the prevalence of adolescent smokers at the age of less than 20 years (66.2%). The effects of smoking can be dangerous to death because cigarettes have 4000 addictive substances such as carbon monoxide and nicotine that are additive and carciogenetic. The content of this cigarette can cause damage and various kinds of diseases in the mouth (infection of the gums), diseases in the bronchi, diseases in the lungs (lung cancer) and diseases of reproductive health. The purpose of this study is to describe the determinants of smoking behavior in SMP Negeri 40 Padang students in 2022. Methodology: Quantitative descriptive research with a cross sectional approach. The study was conducted from January to July 2022 with a total sample of 102 people. The variables of this study are smoking behavior, level of knowledge, attitude, reasons for psychology, parental influence, peer influence, and cigarette advertising influence. The research instrument uses a questionnaire that has been tested for validity and reliability. Data processing by univariate, bivariate and multivariate analysis. Discussion: Results of analysis with prevalence of smoking behavior in students (56.9%), high level of knowledge (55.9%), positive attitude (61.8%), negative psychological reasons (46.1%), influence of supportive parents (84.3%), Influence of supportive Peers (52.9%), Influence of supportive Cigarette Ads (56.9%). Parental influence variables (p-value = 0.011 POR= 5.062), knowledge (p-value = 0.048 POR = 2.460) and attitude (p-value = 0.029 POR = 2.800) had an association with smoking behavior. Conclusion: Parental Influence Variable is the most dominant variable. Conduct socialization about the dangers of cigarettes periodically once a month.
Keywords: Smoking Behavior, Students, Parental Influence
Identifikasi Parasit pada Ikan Bandeng (Chanos chanos F) yang Dibudidayakan pada Tambak Dinas Ketahanan Pangan dan Perikanan Kabupaten Malaka
Authors: Nahak Maksimianus , Fallo Gergonius , Pakaenoni Gonsianus 
Published: February 2024

Ikan bandeng (Chanos chanos F) merupakan salah satu jenis ikan air payau yang mempunyai nilai ekonomis tinggi dan mempunyai prospek cukup baik untuk dikembangkan. Budidaya ikan bandeng merupakan budidaya air payau dimana salinitasnya berada diantara salinitas air laut dan juga air tawar. Tujuan dari penelitian ini untuk mengidentifikasi jenis parasit apa saja yang menginfeksi ikan bandeng, untuk mengetahui prevalensi dan intensitas serangan parasit pada ikan bandeng, unruk mengetahui parameter kualitas air di tambak Dinas Ketahanan Pangan dan Perikanan Kabupaten Malaka. Penelitian ini dilaksanankan pada bulan April sampai Juli 2023. Hasil identifikasi mengenai tingkat serangan ektoparasit dan endoparasit pada 30 ekor ikan bandeng (Chanos chanos F), pada Tambak Dinas Ketahanan Pangan dan Perikanan Kabupaten Malaka terdapat dua jenis parasit. Jenis parasit yang ditemukan dalam penelitian ini yaitu Dactylogyrus sp. dan Camallanus sp. Berdasarkan hasil penelitian yang telah dilakukan dapat di simpulkan bahwa : Jenis parasit yang dapat mengifeksi ikan bandeng dalam penelitian ini adalah Dactylogyrus sp dan camallanus sp nilai prevalensi Dactylogyrus sp adalah 10% (infeksi sering), nilai prevalensi camallanus sp 6,67 % (infeksi kadang), sedangkan nilai kualitas air yaitu: kecerahan air 23cm tergolong sangat baik bagi tambak ikan bandeng dan salinitas air 0,66ppt maka dikategorikan kedalam air payau.
Kata kunci : Identifikasi parasit, Ikan Bandeng.
II Simpósio Internacional de Fisiologia do Exercício e Saúde da Universidade Federal de Viçosa
Authors: Moreira Osvaldo Costa , Pussieldi Guilherme de Azambuja , Trigo Ricardo Wagner de Mendonça , Oliveira Claudia Eliza Patrocínio de , Carneiro Júnior Miguel Araújo , Teodoro Bruno Gonzaga , Brandão Camila Fernanda Costa e Cunha Moraes , Brito Ciro José de , Matos Dihogo Gama de , Bedoya Edison Andrés Pérez , Aidar Felipe José , Arantes Francielle de Assis , Venturini Gabriela Rezende de Oliveira , Encarnação Irismar Gonçalves Almeida da , Ferreira Júnior João Batista , Salgado José Vitor Vieira , Oliveira Lenice Kappes Becker , Fernandes Lidiane Aparecida , Santos Lucas Vieira , Cerqueira Matheus Santos , Mazini Filho Mauro Lúcio , Marocolo Júnior Moacir , Amorim Paulo Roberto Santos , Encarnação Samuel Gonçalves Almeida da , Silva Sandro Fernandes da , Chaves Suene Franciele Nunes , Segheto Wellington 
Published: February 2024

II Simpósio Internacional de Fisiologia do Exercício e Saúde
17 e 18 de novembro de 2023
Universidade Federal de Viçosa - Campus Florestal
Florestal, Minas Gerais, Brasil
Variability of intervertebral joint stiffness between specimens and spine levels
Authors: Gould Samuele L. , Davico Giorgio , Liebsch Christian , Wilke Hans-Joachim , Cristofolini Luca , Viceconti Marco 
Published: February 2024

Introduction: Musculoskeletal multibody models of the spine can be used to investigate the biomechanical behaviour of the spine. In this context, a correct characterisation of the passive mechanical properties of the intervertebral joint is crucial. The intervertebral joint stiffness, in particular, is typically derived from the literature, and the differences between individuals and spine levels are often disregarded.Methods: This study tested if an optimisation method of personalising the intervertebral joint stiffnesses was able to capture expected stiffness variation between specimens and between spine levels and if the variation between spine levels could be accurately captured using a generic scaling ratio. Multibody models of six T12 to sacrum spine specimens were created from computed tomography data. For each specimen, two models were created: one with uniform stiffnesses across spine levels, and one accounting for level dependency. Three loading conditions were simulated. The initial stiffness values were optimised to minimize the kinematic error.Results: There was a range of optimised stiffnesses across the specimens and the models with level dependent stiffnesses were less accurate than the models without. Using an optimised stiffness substantially reduced prediction errors.Discussion: The optimisation captured the expected variation between specimens, and the prediction errors demonstrated the importance of accounting for level dependency. The inaccuracy of the predicted kinematics for the level-dependent models indicated that a generic scaling ratio is not a suitable method to account for the level dependency. The variation in the optimised stiffnesses for the different loading conditions indicates personalised stiffnesses should also be considered load-specific.
Association between periodontitis and endometriosis: a bidirectional Mendelian randomization study
Authors: Jin Bilun , Wang Pengfei , Liu Peiqi , Wang Yijie , Guo Yi , Wang Chenxu , Jia Yue , Zou Rui , Dong Shaojie , Niu Lin 
Published: February 2024

IntroductionA potential association between periodontitis and endometriosis has been indicated in previous observational studies. Nevertheless, the causal link between these two disorders has not been clarified.MethodsBased on publicly available genome-wide association study (GWAS) summary datasets, we conducted a bidirectional Mendelian randomization (MR) study to investigate the relationship between periodontitis and endometriosis and its subtypes. Single nucleotide polymorphisms (SNPs) strongly associated with candidate exposures at the genome-wide significance level (P &lt; 5 × 10−8) were selected as instrumental variables (IVs). The inverse variance-weighted regression (IVW) was performed to estimate the causal effect of periodontitis on endometriosis. We further conducted two sensitivity analyses, MR-Egger and weighted median, to test the validity of our findings. The main results were replicated via data from the UK Biobank. Finally, a reverse MR analysis was performed to evaluate the possibility of reverse causality.ResultsThe IVW method suggested that periodontitis was positively associated with endometriosis of the pelvic peritoneum (OR = 1.079, 95% CI = 1.016 to 1.146, P = 0.014). No causal association was indicated between periodontitis and other subtypes of endometriosis. In reversed analyses, no causal association between endometriosis or its subtypes and periodontitis was found.ConclusionsOur study provided genetic evidence on the causal relationship between periodontitis and endometriosis of the pelvic peritoneum. More studies are necessary to explore the underlying mechanisms.
Long-term treatment with Perampanel of Chinese patients with focal-onset seizures, especially in sleep-related epilepsy: a prospective real-world observational study
Authors: Xu Ye , Wang Qinyue , Zhang Yufei , Chen Yuncan , Xu Lan , Zhu Guoxing , Ma Chunlai , Wu Xunyi 
Published: February 2024

BackgroundThere is currently a lack of studies examining the long-term therapeutic effectiveness of the third-generation anti-sezure medication, perampanel (PER), for focal-onset seizures (FOS), particularly in Chinese patients with sleep-related epilepsy (SRE). Additionally, the appropriate dosage, plasma concentration, and the relationship between dose and plasma concentration of PER in Chinese patients are still uncertain.MethodsA prospective, single-center, 24-month observational study was conducted in patients diagnosed with FOS, with a focus on patients with SRE. Changes in seizure frequency from baseline, adverse events, and retention rates were analyzed at 12 and 24 months following the start of the treatment. Tolerability was evaluated based on adverse events and discontinuation profiles. PER plasma concentrations were used to assess dose-concentration-response relationships.ResultsA total of 175 patients were included (median age: 25 years; range: 4–72 years; 53. 1% males and 46.9% females), with the SRE population accounting for 49. 1% (n = 86). The patients diagnosed with SRE showed considerably higher response rates than those who did not have this diagnosis (p = 0.025, odds ratio = 3.8). Additionally, the SRE group adhered better to PER treatment (r = 0.0009). Patients with a shorter duration of epilepsy (median: 3 years; range:2–7 years) demonstrated a more favorable therapeutic response to PER (p = 0.032). Throughout the administration of maintenance doses, among the entire FOS population, the concentration of PER (C0) ranged between 101.5 and 917.4 ng/mL (median, 232.0 ng/mL), and the mean plasma concentration of PER in the responders was 292.8 ng/mL. We revealed a linear relationship between PER dose and plasma concentration, regardless of whether PER was used as monotherapy or add-on therapy. The retention rates were 77.7% and 65. 1% at 12 and 24 months, respectively. Drug-related adverse events occurred in 45.0% of the patients and were mostly manageable.ConclusionPER effectively reduced seizure frequency in Chinese patients with FOS, particularly in those with SRE, over a 24-month period. The treatment was well-tolerated and had a clear linear dose-plasma concentration relationship.
Evaluation of the photoprotective and antioxidant potential of an avobenzone derivative
Authors: Pasuch Gluzezak Ana Júlia , Dos Santos Jean Leandro , Maria-Engler Silvya Stuchi , Gaspar Lorena Rigo 
Published: February 2024

Solar radiation can cause damage to the skin, and the use of sunscreens is one of the main protective measures. However, photounstable ultraviolet (UV) filters can generate photoproducts and reactive oxygen species (ROS). Adding antioxidants, such as resveratrol, to enhance the action of UV filters in sunscreens is an interesting strategy for reducing the damage caused by UV radiation exposure. However, new compounds must have their stability, safety and efficacy guaranteed. Avobenzone, a commonly used UV filter, stands out as a promising candidate for structural modification to enhance its stability. Its molecular hybridization with other UV filters and antioxidants can lead to safer and more effective compounds. In this study, the photoprotective and antioxidant potential of a derivative of avobenzone, hybridized with resveratrol’s molecule, was evaluated using in vitro models of cells in monolayer and reconstructed human skin (RHS). Phototoxic potential was assessed using fibroblasts, while the antioxidant activity was measured using the DCFH2-DA probe in HaCaT keratinocytes and in-house RHS. The derivative exhibited UV absorption and demonstrated photostability. It did not exhibit any phototoxic nor photoreactivity potential. Additionally, it was able to photo stabilize a combination of photounstable UV filters, avobenzone and octyl methoxycinnamate, and to reduce their phototoxic potential. In terms of antioxidant activity, the derivative successfully protected against UVA-induced ROS production in the HaCaT keratinocytes model, showing statistical equivalence to the antioxidant control, quercetin (10 μg/mL). Furthermore, experiments conducted in the RHS model demonstrated a significant reduction of 30.7% in ROS generation compared to the irradiated control. This study demonstrated that structural modifications of avobenzone can lead to the development of a broad spectrum (absorbing UVB and UVA II radiation, as well as a portion of the UVA I radiation), non-phototoxic, non-photoreactive and photostable derivative for sunscreen and anti-aging formulations. This derivative enhances protection against oxidative stress induced by UV radiation and improves the effectiveness of sun protection. In addition to the monolayer model, the use of a standardized in-house RHS model was highly relevant for evaluating the effects of UV radiation and skin aging. This model closely mimics human physiological conditions and enables the testing of new compounds and the investigation of protective mechanisms against skin damage.
Regulasi Pendirian Rumah Ibadat di Indonesia: Tinjauan Asas-asas Pembentukan Hukum
Authors: Sinaga Budiman N.P.D , Siregar Hisar , Raymando Samuel , Sitepu Desy Febrina 
Published: February 2024

This article aims to explain the causes of many laws and regulations regarding the establishment of houses of worship that cannot be implemented. Until now there are still people who reject the establishment of synagogues. Through research, we want to know the principles of the formation of laws and regulations and evaluation of the law on the establishment of houses of worship in Indonesia. The results of the research can be used for the formation of laws on the establishment of better houses of worship. The sources of legal research used are primary and secondary legal materials. Primary legal materials include legislation and court decisions. Secondary legal materials include books, journals, legal dictionaries, as well as commentaries on court decisions. Research sources were collected in the city of Medan. From this research, it can be seen that the laws and regulations regarding the establishment of houses of worship have not paid attention to all the principles of the formation of laws and regulations. In the future, the formation of laws and regulations on the establishment of houses of worship must take into account all the principles of the formation of laws and regulations without exception
The Characteristics Of Tourists Doing Culinary Tour: A Case Study Of Lengkong Street Food Bandung
Authors: Situmorang Monica Sehatna , Suryana Marceilla 
Published: February 2024

Lengkong Street Food is a culinary tourist attraction that is currently popular in Bandung. This study aims to explain the characteristics of tourists visiting Lengkong Street Food Bandung through socio-demographic, geographic, and psychographic aspects and to find out what types of culinary they like and find out the reasons tourists like these culinary delights. Researchers used a descriptive method in this study with observation, interviews with eleven visitors, and documentation techniques. The results of the research based on the socio-demographic characteristics of tourists are dominated by adolescents and adults with female gender. Based on geographical characteristics, tourists come from outside the city of Bandung. Psychographic characteristics, tourists have interests and expectations. This research found that tourists like culinary types such as Dimsum, BBQ, Suqi, and Steak. The reason tourists like this type of cuisine is because it looks unique, attractive, has affordable prices and has adequate supporting facilities, and offers comfort
Keywords: Characteristics of tourists, culinary tourism, Lengkong Street Food Bandung