bluuebunny/crossref_metadata_2025_split huggingface dataset:
Recent Advances with Topotecan in the Treatment of Lung Cancer
Authors: O'Brien Mary , Eckardt John , Ramlau Rodryg 
Published: October 2007

Learning ObjectivesAfter completing this course, the reader will be able to: Describe phase I studies evaluating the pharmacokinetics and early safety data of single-agent oral topotecan.Discuss the results and implications of clinical trials evaluating oral topotecan for small cell lung cancer (SCLC) and non-small cell lung cancer (NSCLC).Explain why topotecan is a good candidate for combination with other novel anticancer agents.Access and take the CME test online and receive 1 AMA PRA Category 1 Credit™ at CME.TheOncologist.com
Indications and Developments of Video-Assisted Thoracic Surgery in the Treatment of Lung Cancer
Authors: Solli Piergiorgio , Spaggiari Lorenzo 
Published: October 2007

Learning ObjectivesAfter completing this course, the reader will be able to: Discuss the role of thoracoscopy in the evaluation of pulmonary nodules and pleural effusion.Describe the role of thoracoscopy in the staging of lung cancer.Discuss the role of thoracoscopy in surgical resection of early-stage lung cancer.Access and take the CME test online and receive 1 AMA PRA Category 1 Credit™ at CME.TheOncologist.com
Retinoblastoma: Review of Current Management
Authors: Chintagumpala Murali , Chevez-Barrios Patricia , Paysse Evelyn A. , Plon Sharon E. , Hurwitz Richard 
Published: October 2007

Learning Objectives
After completing this course, the reader will be able to: Discuss the need for a multidisciplinary approach to the management of children with retinoblastoma.Identify the patient factors that need to be considered when choosing the most appropriate initial and subsequent treatment for a child with retinoblastoma.Describe the role of genetics in the follow-up of retinoblastoma patients.
Access and take the CME test online and receive 1 AMA PRA Category 1 Credit™ at CME.TheOncologist.com
FDA Approval Summary: Vorinostat for Treatment of Advanced Primary Cutaneous T-Cell Lymphoma
Authors: Mann Bhupinder S. , Johnson John R. , Cohen Martin H. , Justice Robert , Pazdur Richard 
Published: October 2007

Learning Objectives
After completing this course, the reader will be able to: Add vorinostat to the armamentarium of drugs for CTCL.Identify the mechanism of action of vorinostat.Identify goals of therapy of CTCL.Identify active CTCL therapies.Identify CTCL response criteria.
Access and take the CME test online and receive 1 AMA PRA Category 1 Credit™ at CME.TheOncologist.com
A Randomized, Open-Label, Multicenter Trial of Immediate Versus Delayed Intervention with Darbepoetin Alfa for Chemotherapy-Induced Anemia
Authors: Charu Veena , Saidman Bruce , Ben-Jacob Ali , Justice Glen R. , Maniam Ajit S. , Tomita Dianne , Rossi Greg , Rearden Timothy , Glaspy John 
Published: October 2007

Abstract
The optimal hemoglobin concentration at which to initiate erythropoietic therapy for chemotherapy-induced anemia (CIA) is not well defined. This randomized, open-label, multicenter study evaluated the ability of darbepoetin alfa (300 μg every 3 weeks) to maintain hemoglobin levels ≥10g/dl in patients with CIA (hemoglobin ≥10.5 g/dl and ≤12.0 g/dl) randomized 1:1 to an immediate-intervention group (received darbepoetin alfa immediately) or observation group (received darbepoetin alfa if hemoglobin fell to &lt;10 g/dl). In 201 evaluable patients, there was a significant difference between the two groups in the Kaplan–Meier proportion of patients with a hemoglobin decrease to &lt;10g/dl during weeks 1–13 (test period) (primary endpoint): 29% for immediate-intervention patients versus 65% for observation patients. Sixty-four patients in the observation group received darbepoetin alfa (delayed-intervention subgroup). The Kaplan–Meier proportion of patients who received transfusions was lower in the immediate-intervention group than in the delayed-intervention subgroup (14% versus 31% for the test period; 17% versus 36% over the whole study). The target hemoglobin level (≥11 g/dl) was achieved by a higher percentage of patients (crude percentage) in less time in the immediate-intervention group (94% in 2 weeks) than in the delayed-intervention subgroup (73% in 6 weeks); hemoglobin endpoints for the delayed-intervention subgroup were calculated from recalibrated study week 1 (the date patients first received darbepoetin alfa). For both groups, a higher mean change in hemoglobin from baseline led to a greater improvement in Functional Assessment of Cancer Therapy–Fatigue scores. In conclusion, immediate intervention resulted in a significantly lower proportion of patients who experienced a decline in hemoglobin, lower requirement for transfusions, and greater proportion of patients achieving and maintaining the target hemoglobin level.
Thermodynamic assessment of the Al–Li system
Authors: Hallstedt Bengt , Kim Olga 
Published: October 2007

Abstract
In the present work a Calphad type thermodynamic assessment of the Al – Li system is presented. The system is dominated by the central AlLi phase, which has an ordered bcc (B32) structure. fcc Al dissolves considerable amounts of Li. If the fcc solid solution is quenched from high temperature, coherent metastable AlLi precipitates with an ordered fcc (L1) structure can form. There are two nearly stoichiometric phases; AlLi and AlLi. The disordered fcc phase and the ordered AlLi phase as well as the disordered bcc phase (Li) and the ordered AlLi phase are described by four-sublattice models. There is a fairly complete set of experimental data available for this system, and most of them are satisfactorily described by the currently optimised parameters.
Thermodynamic modeling of the B2O3–SiO2 and B2O3–Al2O3 systems
Authors: Decterov Sergei A. , Swamy Varghese , Jung In-Ho 
Published: October 2007

Abstract
A complete literature review, critical evaluation, and thermodynamic modeling of the phase diagrams and thermodynamic properties of all oxide phases in the binary systems B2O3 – SiO2 and B2O3 – Al2O3 have been performed. The molten oxide is described by the Modified Quasichemical Model. Discrepancies in the available experimental data have been resolved and an optimized set of self-consistent thermodynamic functions of all phases has been obtained. This thermodynamic database can be used with the FactSageTM thermodynamic computing system to calculate all thermodynamic properties and phase equilibria from 25 °C to above the liquidus temperatures at 1 atm of total pressure and over the entire composition range.
Thermodynamic treatment of uranium dioxide based nuclear fuel
Authors: Thompson W. T. , Lewis B. J. , Corcoran E. C. , Kaye M. H. , White S. J. , Akbari F. , He Z. , Verrall R. , Higgs J. D. , Thompson D. M. , Besmann T. M. , Vogel S. C. 
Published: October 2007

Abstract
Many projects involving nuclear fuel rest on a quantitative understanding of the co-existing phases at various stages of burnup. Since the fission products have considerably different abilities to chemically associate with oxygen, and the metal-to-oxygen molar ratio is necessarily increasing, the chemical potential of oxygen is a function of burnup. Concurrently, well-recognized small fractions of new phases such as inert gas, noble metals, zirconates, etc. also develop. To further complicate matters, the dominant UO2 fuel phase may be non-stoichiometric and most of the minor phases themselves have a variable composition dependent on temperature and possible contact with the coolant in the event of a sheathing breach.
A thermodynamic database has been in development to predict the phases in partially burned CANDU (CANada Deuterium Uranium) nuclear fuel containing the major fission products. The building blocks are the standard Gibbs energies of formation of the many possible compounds expressed as a function of temperature. To these data are added mixing terms associated with the appearance of the component species in particular phases. In operational terms, the treatment rests on the ability to minimize the Gibbs energy in a multicomponent system using the algorithms developed by Eriksson. The treatment, considered applicable in the range 300 to 2000 °C, is capable of handling non-stoichiometry in the UO2 fluorite phase, dilute solution behaviour of significant solute oxides, noble metal inclusions, a second metal solid solution U(Pd – Rh – Ru)3, zirconate, molybdate, and uranate solutions as well as other minor solid phases, and volatile gaseous species. The paper highlights the current capability of an ongoing project.
Development of the supralaryngeal vocal tract in Japanese macaques: Implications for the evolution of the descent of the larynx
Authors: Nishimura Takeshi , Oishi Takao , Suzuki Juri , Matsuda Keiji , Takahashi Toshimitsu 
Published: October 2007

AbstractThe configuration of the supralaryngeal vocal tract depends on the nonuniform growth of the oral and pharyngeal portion. The human pharynx develops to form a unique configuration, with the epiglottis losing contact with the velum. This configuration develops from the great descent of the larynx relative to the palate, which is accomplished through both the descent of the laryngeal skeleton relative to the hyoid and the descent of the hyoid relative to the palate. Chimpanzees show both processes of laryngeal descent, as in humans, but the evolutionary path before the divergence of the human and chimpanzee lineages is unclear. The development of laryngeal descent in six living Japanese macaque monkeys, Macaca fuscata, was examined monthly during the first three years of life using magnetic resonance imaging, to delineate the present or absence of these two processes and their contributions to the development of the pharyngeal topology. The macaque shows descent of the hyoid relative to the palate, but lacks the descent of the laryngeal skeleton relative to the hyoid and that of the EG from the VL. We argue that the former descent is simply a morphological consequence of mandibular growth and that the latter pair of descents arose in a common ancestor of extant hominoids. Thus, the evolutionary path of the great descent of the larynx is likely to be explained by a model comprising multiple and mosaic evolutionary pathways, wherein these developmental phenomena may have contributed secondarily to the faculty of speech in the human lineage. Am J Phys Anthropol, 2008. © 2007 Wiley‐Liss, Inc.
Of stones and monkeys: Testing ecological constraints on stone handling, a behavioral tradition in Japanese macaques
Authors: Leca Jean‐Baptiste , Gunst Noëlle , Huffman Michael A. 
Published: October 2007

AbstractJapanese macaques are known to manipulate stones by displaying various seemingly functionless behavioral patterns, including carrying a stone, rubbing two stones together, or gathering several stones into a pile. This form of solitary object play called stone handling (SH) is a behavioral tradition in Japanese macaques, showing striking intertroop differences in frequency and form. Here, we evaluated two ecologically based hypotheses invoked to account for these differences. We hypothesized that the occurrence and form of SH would be affected by stone availability and the degree of terrestriality. We used standardized sampling methods to assess differences in SH and terrestriality among four captive and six free‐ranging troops of Japanese macaques, and determine site‐specific stone availability. Although we demonstrated that SH is almost exclusively a terrestrial activity, our comparative analyses showed that the number of stones readily available and the relative amount of time spent on the ground by the macaques were not associated with the intertroop differences in the occurrence of SH. Failure to accept the terrestriality and stone availability hypotheses suggests that the performance of SH and the motivation to engage in this activity are both more diverse and more complex than the direct links to time spent on the ground or the number of stones locally available. Other environmental influences and sociodemographic factors should be jointly considered to identify the sources of variation in SH, as a beginning to better understand the constraints on the appearance and subsequent diffusion of stone‐use traditions in nonhuman primates. Am J Phys Anthropol, 2008. © 2007 Wiley‐Liss, Inc.
Thermooxidative ageing of polyoxymethylene, part 1: Chemical aspects
Authors: Fayolle B. , Verdu J. , Bastard M. , Piccoz D. 
Published: October 2007

AbstractThe thermal oxidation of unstabilised POM homopolymer has been studied at 90, 110, and 130°C under various oxygen pressures ranging from 0 to 2.0 MPa by gravimetry and IR spectrometry. This latter reveals essentially the formation of formate (F) groups and alcohols in smaller quantities. The formate growth and mass loss rates increase pseudo hyperbolically with oxygen pressure, the asymptotic level being reached at pressures up to 0.5 MPa. These results lead to propose a mechanistic scheme of radical chain oxidation in which depolymerization is initiated by hydroperoxide unimolecular decomposition, one formate and one chain scission being formed per decomposition event whereas the kinetic chain length of the depolymerization zip is of the order of 100. A kinetic model derived from the mechanistic scheme, taking into account substrate consumption, simulates correctly the shape of kinetic curves and the effect of temperature and oxygen pressure. © 2007 Wiley Periodicals, Inc. J Appl Polym Sci, 2008
Effect of functional group of ferrocene redox substance on the transport properties of newly designed ion exchange membrane prepared from polymer gel
Authors: EL Sayed A. Mounir , Yamasaki Shinya , Yamauchi Akira 
Published: October 2007

AbstractA different newly designed cationic exchange polymer membrane and anionic exchange polymer membrane were introduced, and also the transport properties of these polymeric membranes were investigated in this study. The transport properties of these polymer membranes in contact with ferrocene redox derivatives were estimated by using electrochemical techniques such as cyclicvoltammetry, chronopotentiometry, and chronoamperometry techniques, respectively. The used ferrocene redox substances, which have different functional groups, were (Ferrocenylmethyl) trimethylamonium iodide, FcMA, Ferrocenedimethanol, FcDM, and Ferrocene carboxylic acid, FcCA. It indicated that the performance of a membrane depended on the content of polymer gel, anionic exchange polymer site (20 wt % and 50 wt %) or cationic polymer exchange site (20 wt % and 50 wt %), and the efficiency of the functional groups of cationic and anionic exchange polymer site as well. © 2007 Wiley Periodicals, Inc. J Appl Polym Sci, 2008
Effect of the chain‐transfer‐agent content on the emulsion polymerization process and adhesive properties of poly(n‐butyl acrylate‐co‐acrylic acid) latexes
Authors: Shen Hanzi , Zhang Jiyang , Liu Shuangjin , Liu Guodong , Zhang Liqun , Qu Xiongwei 
Published: October 2007

AbstractThe preparation of a series of poly(n‐butyl acrylate‐co‐acrylic acid) latexes with different contents of chain‐transfer agent are reported, and investigations into the adhesive properties of the latexes were made. The latexes were prepared at a solid content of 50 wt % by a two‐stage sequential emulsion polymerization with the monomers n‐butyl acrylate (BA) and acrylic acid (AA). This process consisted of a batch seed stage (BA), which gave a particle diameter of 112 nm, which was then grown by the semicontinuous addition of monomers to a final diameter of 303 nm. Dynamic light scattering was used to monitor the particle diameters and showed that the particles grew without significant secondary nucleation occurring. The molecular parameters were characterized by gel permeation chromatography and dynamic mechanical analysis. The adhesive properties measured were loop tack force, peel strength and shear resistance according to Fédération Internationale des Fabricants et Transformateurs d'Adhésifs et Thermocollants sur Papiers et Autres Supports (FINAT) test methods. The relationship between pressure‐sensitive properties and molecular parameters, such as gel content and molecular weight, was evaluated. © 2007 Wiley Periodicals, Inc. J Appl Polym Sci, 2008
A viscometric study for adsorption of bovine serum albumin onto the inner surface of glass capillary
Authors: Li Yi , Cai Zhengchun , Zhong Wenxing , Cheng Rongshi 
Published: October 2007

AbstractViscosities of aqueous solutions of bovine serum albumin (BSA) at different temperatures were carefully measured in a common glass capillary Ubbelohde viscometer in the concentration range from dilute down to extremely dilute concentration regions. The adsorption effect occurred in viscosity measurements were theoretically analyzed and discussed. The theory based on the Langmuir isotherms could adequately describe the existing data. The influence of temperature on the adsorption of BSA solution was discussed and a simple adsorption model was proposed. The conformational change of BSA macromolecules happened both in the bulk solution and on the inner surface of glass capillary. © 2007 Wiley Periodicals, Inc. J Appl Polym Sci, 2008
The mediating effect of information availability between organization design variables and environmental practices in the Canadian hotel industry
Authors: Sharma Sanjay 
Published: October 2007

AbstractThis study examines whether providing employees with information about environmental impacts, industry practices, technologies, regulations and benchmarking of environmental practices mediates the influence of organization design variables on environmental impact reduction. The study finds that both organization design variables (discretionary slack, coordination mechanisms and performance evaluation) and information availability have a direct influence on environmental impact reduction practices in the Canadian hotel industry. However, information availability partially mediates the influence of organization design variables, indicating that effecting changes in organization design alone may be less effective in generating proactive environmental practices without providing employees with information and benchmarking of industry environmental practices. Copyright © 2007 John Wiley & Sons, Ltd and ERP Environment.
Teaching computer‐aided mechanism design and analysis using a high‐level mechanism toolkit
Authors: Campbell Matt , Cheng Harry H. 
Published: October 2007

AbstractA pedagogically effective teaching strategy that integrates computer‐aided design and programming into a course on mechanism analysis and design is presented. Mechanism analysis is enhanced when coupled with computer programming that allows students to find solutions to more complex systems than would otherwise be possible. Web‐based distance learning is part of the class and students also learn how to create these kinds of materials themselves. Students can better understand the course material through an integrated computing environment. By solving mechanism design problems in C/C++, the programming skills gained in the course are widely applicable in other areas of engineering. Ch, a C/C++ interpreter, is used to incorporate programming and mechanism design because of its high‐level numerical and graphical plotting capabilities, scripting capability, and a mechanism toolkit with easy and quick animation. A student project is presented as an example to show how computer programming is integrated for effective learning. This teaching strategy has been actively used at the University of California, Davis for several years in an undergraduate course in computer‐aided mechanism design and has been adopted by other universities as well. © 2007 Wiley Periodicals, Inc. Comput Appl Eng Educ 15: 277–288, 2007; Published online in Wiley InterScience (www.interscience.wiley.com); DOI 10.1002/cae.20156
V2AlC, V4AlC3‐x (x ≈ 0.31), and V12Al3C8: Synthesis, Crystal Growth, Structure, and Superstructure.
Authors: Etzkorn Johannes , Ade Martin , Hillebrecht Harald 
Published: October 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Controlled Chemical Reduction of Uranyl Salts into UX4(MeCN)4 (X: Cl, Br, I) with Me3SiX Reagents.
Authors: Berthet Jean‐Claude , Siffredi Gerald , Thuery Pierre , Ephritikhine Michel 
Published: October 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
A Family of Octahedral Rhenium Cluster Complexes [Re6Q8(H2O)n(OH)6‐n] n‐4 (Q: S, Se; n = 0—6): Structural and pH‐Dependent Spectroscopic Studies.
Authors: Brylev Konstantin A. , et al. et al. 
Published: October 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Synthesis, Structure and Magnetic Characterization of Two Phosphate Compounds Related with the Mineral Struvite: KNiPO4×6H2O and NaNiPO4×7H2O.
Authors: Trobajo Camino , Salvado Miguel A. , Pertierra Pilar , Alfonso Belen F. , Blanco Jesus A. , Khainakov Serguei A. , Garcia Jose R. 
Published: October 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Synthesis of Polymer‐Supported Fesulphos Ligands and Their Application in Asymmetric Catalysis.
Authors: Martin‐Matute Belen , Pereira Susana Isabel , Pena‐Cabrera Eduardo , Adrio Javier , Silva Artur M. S. , Carretero Juan C. 
Published: October 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Interrelation Between the Structure and Cyclization Direction of o‐Alkynylbenzenediazonium Salts.
Authors: Zol'nikova N. A. , Fedenok L. G. , Peresypkina E. V. , Virovets A. V. 
Published: October 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Palladium‐Catalyzed Cross‐Coupling of Aryl or Vinyl Iodides with Ethyl Diazoacetate.
Authors: Peng Cheng , Cheng Jiajia , Wang Jianbo 
Published: October 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Bidentate N,O‐Prolinate Ruthenium Benzylidene Catalyst Highly Active in RCM of Disubstituted Dienes.
Authors: Samec Joseph S. M. , Grubbs Robert H. 
Published: October 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Butadiene Hydroamination with Aqueous Ammonia Catalyzed by Palladium(II) Sulfoxide Complexes.
Authors: Dzhemilev U. M. , Tolstukov G. A. , Khusnutdinov R. I. , Shchadneva N. A. , Baiguzina A. R. , Oshnyakova T. M. , Mukhametshina L. F. 
Published: October 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Asymmetric Hydrosilylation of Prochiral Ketones Catalyzed by Nanocrystalline Copper(II) Oxide.
Authors: Kantam M. Lakshmi , Laha Soumi , Yadav Jagjit , Likhar Pravin R. , Sreedhar B. , Choudary B. M. 
Published: October 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.