bluuebunny/crossref_metadata_2025_split huggingface dataset:
ChemInform Abstract: Organocatalytic Asymmetric 5‐Hydroxypyrrolidine Synthesis: A Highly Enantioselective Route to 3‐Substituted Proline Derivatives.
Authors: Rios Ramon , Ibrahem Ismail , Vesely Jan , Sunden Henrik , Cordova Armando 
Published: February 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis of Isoindol‐1‐ylphosphonate Derivatives via Pd(0)‐Catalyzed Reaction of α‐Amino (2‐Alkynylphenyl) Methylphosphonate with Aryl Iodide.
Authors: Ding Qiuping , Wang Bing , Wu Jie 
Published: February 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Convenient Synthesis of Highly Functionalized Pyrazolines via Mild, Photoactivated 1,3‐Dipolar Cycloaddition.
Authors: Wang Yizhong , Rivera Vera Claudia I. , Lin Qing 
Published: February 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Spiro‐Heterocyclization of Pyrrolobenzoxazinetriones (I) Effected by Thiourea.
Authors: Babenysheva A. V. , Maslivets V. A. , Maslivets A. N. 
Published: February 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis of 4‐Amino‐5‐ (4,6‐diphenyl‐2‐pyrimidinyl)‐3,4‐dihydro‐2H‐1,2,4‐triazole‐3‐thione and Its Reaction with C‐Electrophiles.
Authors: Mekuskiene G. , Vainilavicius P. 
Published: February 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis of Furanyl and Oxazolyl N‐Substituted Piperidine and Imidazoline Salts as Potential Agonists of M1 Muscarinic Receptors.
Authors: Aguado Andreina , Boulos John , Carreras Anladys , Montoya Angelica , Rodriquez Judith 
Published: February 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Tandem Furo[3,4‐b]pyridine Formation—Diels—Alder Reaction: An Approach to the Synthesis of Nitrogen Containing Heterocyclic Analogues of 1‐Arylnaphthalene Lignans.
Authors: Jana Gouranga P. , Ghorai Binay K. 
Published: February 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: A Novel Synthesis of Benzo[h]quinolones and Study of Their Fluorescence Properties.
Authors: Jachak Madhukar N. , Kendre Dhananjay B. , Avhale A. B. , Toche Raghunath B. , Sabnis Ram W. 
Published: February 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: An Efficient Synthesis of Fluorine‐Containing Substituted Spiro[piperidine‐4,4′‐pyrano[3,2‐c]quinoline]‐3′‐carbonitrile by Nonconventional Methods.
Authors: Dandia Anshu , Gautam Sangeeta , Jain Anuj Kumar 
Published: February 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: New Efficient Route to Dissymmetric 2,4‐Di(het)aryl‐pyrido[3,2‐d]pyrimidines via Regioselective Cross‐Coupling Reactions.
Authors: Tikad Abdellatif , Routier Sylvain , Akssira Mohamed , Leger Jean‐Michel , Jarry Christian , Guillaumet Gerald 
Published: February 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Multicomponent Domino [4 + 2]/[3 + 2] Cycloadditions of Nitroheteroaromatics: An Efficient Synthesis of Fused Nitrogenated Polycycles.
Authors: Chataigner Isabelle , Piettre Serge R. 
Published: February 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Pd‐Mediated Synthesis of Novel Pentacyclic Benzoazepino[2,1‐a]isoindoles from Enamides of Baylis—Hillman Adducts.
Authors: Gowrisankar Saravanan , Lee Hyun Seung , Lee Ka Young , Lee Ji‐Eun , Kim Jae Nyoung 
Published: February 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Two Drimane‐Type Sesquiterpenes, Strobilactones A and B, from the Liquid Culture of the Edible Mushroom Strobilurus ohshimae.
Authors: Shiono Yoshihito , Hiramatsu Fuminori , Murayama Tetsuya , Koseki Takuya , Funakoshi Takayuki , Ueda Koji , Yasuda Hironori 
Published: February 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Facile Regiospecific Syntheses of N‐α,N‐1(τ)‐Dialkyl‐L‐histidines.
Authors: Nayak Surendra Kumar , Monga Vikramdeep , Kaur Navneet , Jain Rahul 
Published: February 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis of 2‐Iodoglycals, Glycals, and 1,1′‐Disaccharides from 2‐Deoxy‐2‐iodopyranoses under Dehydrative Glycosylation Conditions.
Authors: Rodriguez Miguel Angel , Boutureira Omar , Matheu M. Isabel , Diaz Yolanda , Castillon Sergio , Seeberger Peter H. 
Published: February 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Revised Structure of Kasarin, an Antibacterial Pyrazinone Compound from the Marine Microorganism Hyphomycetes sp.
Authors: Kita Masaki , Miwa Ryoka , Widianti Triana , Ozaki Yoshikazu , Aoyama Sachiko , Yamada Kaoru , Uemura Daisuke 
Published: February 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Spirofungin A: Stereoselective Synthesis and Inhibition of Isoleucyl‐tRNA Synthetase.
Authors: Marjanovic Jasmina , Kozmin Sergey A. 
Published: February 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Prediction of Mutagenic Toxicity by Combination of Recursive Partitioning and Support Vector Machines.
Authors: Liao Quan , Yao Jianhua , Yuan Shengang 
Published: February 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Fabrication of Ferromagnetic Iron Carbide Nanoparticles by a Chemical Vapor Condensation Process.
Authors: Lee D. W. , Yu J. H. , Kim B. K. , Jang T. S. 
Published: February 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Chemistry of Hydrazonoalkanenitriles
Authors: Riyadh Sayed M. , Abdelhamid Ismail A. , Ibrahim Hamada M. , Al‐Matar Hamad M. , Elnagdi Mohamed H. 
Published: February 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Catalytic Hydrogenation of Polar Organic Functionalities Based on Ru‐Mediated Heterolytic Dihydrogen Cleavage
Authors: Ito Masato , Ikariya Takao 
Published: February 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Glycosylation Reaction via a Mild and Efficient One‐Pot Reaction Using Doped Natural Phosphate with Iodine as Catalyst
Authors: Lazrek H. B. , Ouzebla D. , Baddi L. , Vasseur J. J. 
Published: February 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Lipoxygenase Inhibitors: A Comparative QSAR Study Review and Evaluation of New QSARs
Authors: Pontiki Eleni , Hadjipavlou‐Litina Dimitra 
Published: February 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis of C8‐Modified 2′‐Deoxyadenosine with Carcinogenic Arylamines
Authors: Jacobsen M. I. , Meier C. 
Published: February 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Efficient Synthesis of Benzamide Riboside, a Potential Anticancer Agent
Authors: Bonnac Laurent F. , Gao Guang‐Yao , Chen Liqiang , Patterson Steven E. , Jayaram Hiremagalur N. , Pankiewicz Krzysztof W. 
Published: February 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis of a New Ribose Modified Analogue of Cyclic Inosine Diphosphate Ribose
Authors: Oliviero Giorgia , Borbone Nicola , Amato Jussara , D'Errico Stefano , Piccialli Gennaro , Varra Michela , Mayol Luciano 
Published: February 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Asymmetric synthesis of bicyclic piperidines via L‐proline catalyzed aldol reaction of 3‐phthalimidopropanal
Authors: Zhang Fanglin , Peng Yiyuan , Gong Yuefa 
Published: February 2008

AbstractA highly enantioselective approach for preparing optically active bicyclic piperidines is described. The key step for introducing chiral centers was a L‐proline catalyzed direct enantioselective aldol reaction of 3‐phthalimidopropanal with aliphatic ketones. In the reactions with alicyclic ketones, a highly enantioselective formation of anti‐2‐(3‐phthalimido‐1‐hydroxypropyl)cycloketones 1a–1b (>99% ee) was observed. The aldol products 1 could be subsequently converted into bicyclic piperidines 2 via a consecutive reductive deprotection, acylation, ring closure, and hydrolysis. Chirality, 2008. © 2008 Wiley‐Liss, Inc.
Untersuchung der Kristallisation amorpher Lactose in Milchpulver anhand Dynamischer Wasserdampfsorption
Authors: Danzl W. , Ziegleder G. 
Published: February 2008

AbstractMilchpulver enthalten Lactose in amorpher Form und sind daher hygroskopisch und instabil. Bei unkontrollierter Kristallisation der amorphen Lactose kann es zu Schwierigkeiten durch Verklumpen oder Bräunungsreaktionen in Milchpulvern oder trockenmilchhaltigen Folgeprodukten kommen. Um die Kristallisationsneigung der amorphen Lactose zu bestimmen, wurden geeignete Methoden anhand dynamischer Wasserdampfsorption (Dynamic Vapour Sorption –DVS) entwickelt und an Sprühvollmilchpulver demonstriert.
Changing indications for surgery in patients with stage IV breast cancer
Authors: Morrogh Mary , Park Anna , Norton Larry , King Tari A. 
Published: February 2008

AbstractBACKGROUNDEvolving concepts of cancer biology and emerging evidence of a potential survival benefit from local surgery have raised the question of an expanded role for surgery in select patients with metastatic breast cancer (MBC). To determine whether such developments have influenced clinical practice, the authors evaluated surgical practice patterns in the study institution over the last 15 years.METHODSTwo institutional databases were screened to identify patients with MBC who underwent breast surgery (1990–2005). Retrospective review was conducted to assess trends over time and to evaluate the role of surgery in the more modern era (1995–2005).RESULTSThe overall frequency of mastectomy remained stable over time (1.7%); however, between early (1990–1995) and late (2000–2005) periods the rate of ‘symptom control’ mastectomy decreased (41% to 25%), whereas the rate of ‘local control’ mastectomy increased (34% to 66%). Conversely, the overall frequency of wide‐local excision (WLE) increased over time (1995–2001), from 1% to 9% (P < .001) with no differences noted between rates of symptom control or local control procedures. In the modern era (1995–2005), 256 of 12,529 patients (2%) with MBC underwent breast surgery (33% mastectomy, 52% WLE); most frequently to ‘optimize local control’ (50%) and primarily in the setting of limited/stable distant disease. Surgery was performed for palliation in only 19% of patients. At a median follow‐up of 33.9 months (range, 0–198.7 months), 136 of 256 patients (53%) in this cohort remained alive; 88% were free of local disease.CONCLUSIONSAlthough surgery in MBC has historically been reserved for palliation, the authors observed a decreasing rate of traditional ‘toilet mastectomy’ and a broadened surgical approach to the asymptomatic patient. When viewed in parallel with evolving concepts in cancer biology, these data reflect a change in the traditional approach to patients with MBC and warrant further investigation. Cancer 2008. ©2008 American Cancer Society.
Proxy perspectives regarding end‐of‐life care for persons with cancer
Authors: Bakitas Marie , Ahles Tim A. , Skalla Karen , Brokaw Frances C. , Byock Ira , Hanscom Brett , Lyons Kathleen Doyle , Hegel Mark T. 
Published: February 2008

AbstractBACKGROUNDEach year, greater than a half million people die of cancer in the U.S. Despite progress in increasing access to palliative oncology services, end‐of‐life care still needs improvement. Measuring the quality of the end‐of‐life experience is difficult because of patient debility and reduced consciousness as death approaches. Family proxies have been proposed as valuable informants regarding the quality of end‐of‐life care. This article describes family proxy perspectives concerning care at the end of life in patients who died of advanced cancer.METHODSIn the context of a novel outpatient palliative care demonstration project, 125 family proxy respondents completed a structured survey by telephone 3 months to 6 months after the patient's death from breast, lung, or gastrointestinal cancer. Four key quality of care indicators were measured: decision‐making and physician communication, location of death, hospice involvement, and end‐of‐life symptoms.RESULTSProxies reported that 78% to 81% of patients completed at least 1 form of advance directive and approximately half of them were helpful in guiding care. Communication with physicians regarding end‐of‐life treatment wishes occurred in 67% of cases, but only 57% of the patients actually made a plan with their physician to ensure that their wishes were followed. The majority of patients died in their location of choice, most often at home, and greater than half had hospice involvement for an average of 41.8 days before death. During the last week of life, the majority of patients experienced troublesome physical and emotional symptoms.CONCLUSIONSMeasurement of proxy perspectives is feasible as an indicator of the quality of end‐of‐life care, and the results of the current study provide actionable data for areas of improvement in palliative oncology care. Cancer 2008. © 2008 American Cancer Society.
An Acoustically Driven Microliter Flow Chamber on a Chip (μFCC) for Cell–Cell and Cell–Surface Interaction Studies
Authors: Schneider Matthias F. , Guttenberg Zeno , Schneider Stefan W. , Sritharan Kumudesh , Myles Vanessa M. , Pamukci Umut , Wixforth Achim 
Published: February 2008

AbstractA novel method for pumping very small volumes of liquid by using surface acoustic waves is employed to create a microfluidic flow chamber on a chip. It holds a volume of only a few μl and its planar design provides complete architectural freedom. This allows for the reconstruction of even complex flow scenarios (e.g. curvatures, bifurcations and stenosis). Addition of polymer walls to the planar fluidic track enables cell culturing on the chip surface and the investigation of cell–cell adhesion dynamics under flow. We demonstrate the flexibility of the system for application in many areas of microfluidic investigations including blood clotting phenomena under various flow conditions and the investigation of different stages of cell adhesion.
A yEGFP‐based reporter system for high‐throughput yeast two‐hybrid assay by flow cytometry
Authors: Chen Jun , Zhou Jianhong , Bae Weon , Sanders Claire K. , Nolan John P. , Cai Hong 
Published: February 2008

AbstractThe yeast two‐hybrid (Y2H) assay is a widely used method to study protein–protein interactions, a major objective in postgenome research. Despite the tremendous utility of the Y2H assay, several issues including accuracy, speed, automation, and cost‐effectiveness limit its application in high‐throughput analysis. We have created an improved Y2H assay reporter system by integrating the codon‐optimized yeast enhanced green fluorescent protein (yEGFP) gene into the ADE2 locus of the AH109 yeast strain and evaluated reporter expression using the strong and weak triggers via flow cytometry. We also performed flow cytometry‐based Y2H assays in liquid cultures as well as in a cDNA library screening. We have shown that yEGFP, but not EGFP, is a sensitive Y2H reporter for flow cytometric detection. We also show that this yEGFP‐based Y2H could be easily adapted to high‐throughput format without conventional agar plating. Moreover, our data demonstrate that this system can be used for cDNA library screening. We have developed sensitive and efficient flow cytometry‐based Y2H assay system that is well suited for large‐scale protein–protein interaction identification and characterization. When compared with the conventional plate and filter membrane‐based nutrient and colorimetric analysis, our flow cytometric assay offers convenient, quantitative, and faster reporter analysis compatible with existing liquid handling robots. © 2008 International Society for Analytical Cytology