bluuebunny/crossref_metadata_2025_split huggingface dataset:
Early mourning? Petitionary versus posthumous ritual in Ezekiel xxiv
Authors: Lipton Diana 
Published: April 2006

AbstractEzekiel xxiv 15-24 contains God's perplexing announcement that the prophet's wife is about to die but that he must not mourn her. This prohibition against mourning is almost invariably interpreted as God's attempt to limit Ezekiel's response, ritual and perhaps also emotional, to his wife's death, foreshadowing Israel's reaction following the destruction of the temple. Yet it is difficult to see how, and more importantly why, God hoped to restrict conventional, posthumous mourning either for the prophet's wife or for the temple. Ez. xxiv 15–24 differs significantly from Jer. xvi 1–18, where posthumous mourning is restricted for reasons that are made clear, but has striking parallels to II Sam. xii 13–23, where the mourning described is not posthumous but rather petitionary. Petitionary mourning rituals are undertaken before a death or disaster in the hope of averting it. The prohibition against mourning in Ez. xxiv 15–24 may be read as a divine attempt to block prophetic intercession (cf. perhaps Ez. iii 25–27). God is determined to destroy the temple and prohibits Ezekiel and, by extension, Israel, from undertaking petitionary mourning rituals that might have persuaded Him to change His mind.
Intentionality, Morality, and Their Relationship in Human Judgment
Authors: Malle Bertram 
Published: April 2006

AbstractThis article explores several entanglements between human judgments of intentionality and morality (blame and praise). After proposing a model of people's folk concept of intentionality I discuss three topics. First, considerations of a behavior's intentionality affect people's praise and blame of that behavior, but one study suggests that there may be an asymmetry such that blame is more affected than praise. Second, the concept of intentionality is constitutive of many legal judgments (e.g., of murder vs. manslaughter), and one study illustrates people's subtle considerations of intentionality in making those judgments. Third, controversial recent studies suggest that moral considerations can affect judgments of intentionality, and an asymmetry may exist such that blame affects those judgments more than praise. I report two new studies that may shed light on these recent findings, and I discuss several theoretical models that might account for the impact of moral considerations on intentionality judgments and for the relationship between the two more generally.
Developing Conceptions of Responsive Intentional Agents
Authors: Wellman Henry , Miller Joan 
Published: April 2006

AbstractWe argue that folk psychology and folk morality both develop from the same core conception of persons, namely a concept of a responsive intentional agent. Key features of this conception are evident in infancy and develop universally in the preschool years across cultures and languages. Even these early understandings develop, shaped and specified via processes of cognitive construction intertwined with cultural constructs of persons provided within interactive culturally constituted, communicative experiences of childhood. The result is culturally variable endpoints of social cognitive development, that is, culturally variable folk psychologies and folk moralities. We underwrite this argument with data from studies of theory of mind understandings, moral judgments, person description and explanation, and autobiographical memory, research that spans from infancy to adulthood and includes a variety of cultural communities.
Schadenfreude: A Case Study of Emotion as Situated Discursive Display
Authors: Wang Yong , Roberts Carl 
Published: April 2006

AbstractMost Americans are aware that joy was expressed in the Arab world over the suffering inflicted on Americans with the September 11th attacks on the World Trade Center and Pentagon. Less known is that such Schadenfreude was expressed by many Chinese citizens as well. This paper analyzes a sample of texts from postings on the Beijing University bulletin board system. Following a discursive approach to the social psychological study of emotion, we consider discourse as the means whereby power relations are asserted and maintained. These power relations comprise a domain within which actions and emotional displays are occasioned and understood. Based on the texts analyzed here, Schadenfreude can be understood as a discursive display by an observer of an event. This event must be recognized in terms of a "discursive history" within which a bully (here, the United States) has repeatedly violated the "rights" of bullied parties. In accordance with this discursive history, the event is seen as a reversal-in-tradition whereby rights presumed by the bully are violated. Finally, the observer must disidentify with the bully. As a discursive display, Schadenfreude not only comprises the overt performance of the observer's taken-for-granted understanding of the bully-as-bully, but also displaces any potential alternative discourse such as expressions of sympathy other observers may have for any target of such an event. This approach complements the social constructionist perspective within the literature on the sociology of emotions, but departs fundamentally from this literature's essentialist (or psycho-physiological) perspective.
Accessio and specificatio reconsidered
Authors: Plisecka Anna 
Published: April 2006

AbstractContrary to the dominant opinion of contemporary Roman law studies, accessio and specificatio were not considered in ancient Roman law as independent modes of acquisition of ownership. They became regarded as such only in the 12th Century. In ancient Roman law, what later came to be called accessio caused only an extension of the ownership of the principal thing to include also the accessory without, however, giving rise to a new ownership. On the other hand, what later came to be called specificatio caused the extinction of the object, both from the physical and from the juridical point of view. If, in place of the extinguished thing a new one came into existence it could have been acquired by occupatio.
Since the technical juridical terms accessio and specificatio were unknown to the Roman jurists, the cases provided by ancient sources cannot be clearly divided into these categories. Furthermore such classifications, since external to the sources, create superfluous problems. In order to attribute ownership the Roman jurists examined the identity of an object rather than classified cases as accessio or specificatio.
The principal texts on which the argumentation is based are: D. 6.1.5.1pr.–1, D. 6.1.3.2, D. 41.1.7.7 und D. 41.1.7.8–9.
KIAA0101 (OEACT-1), an expressionally down-regulated and growth-inhibitory gene in human hepatocellular carcinoma
Authors: Guo Minglei , Li Jinjun , Wan Dafang , Gu Jianren 
Published: April 2006

Abstract

Background
Our previous cDNA array results indicated KIAA0101 as one of the differentially expressed genes in human hepatocellular carcinoma (HCC) as compared with non-cancerous liver. However, it is necessary to study its expression at protein level in HCC and its biological function for HCC cell growth.

Method
Western blot and tissue array were performed to compare KIAA0101 protein expression level in paired human HCC and non-cancerous liver tissues from the same patients. Investigation of its subcellular localization was done by using dual fluorescence image examination and enriched mitochondrial protein Western blot analysis. The in vitro cell growth curve was used for examing the effect of over-expression of KIAA0101 in HCC cells. FACS was used to analyze the cell cycle pattern in KIAA0101 expression positive (+) and negative (-) cell populations isolated by the pMACSKKII system after KIAA0101 cDNA transfection.

Results
Western blot showed KIAA0101 protein expression was down-regulated in HCC tissues as compared with their counterpart non-cancerous liver tissues in 25 out of 30 cases. Tissue array also demonstrated the same pattern in 161 paired samples. KIAA0101 was predominantly localized in mitochondria and partially in nuclei. KIAA0101 cDNA transfection could inhibit the HCC cell growth in vitro. In cell cycle analysis, it could arrest cells at the G1 to S phase transition.

Conclusion
KIAA0101 protein expression was down-regulated in HCC. This gene could inhibit the HCC cell growth in vitro and presumably by its blocking effect on cell cycle.
Hyeropic shift after LASIK induced Diffuse lamellar keratitis
Authors: Dada Tanuj , Pangtey Mayank S , Sharma Namrata , Vajpayee Rasik B , Jhanji Vishal , Sethi Harinder Singh 
Published: April 2006

Abstract

Background
Diffuse lamellar keratitis (DLK) is a relatively new syndrome that is increasingly being reported after LASIK. We have observed that a hyperopic shift may be associated with the occurrence of this diffuse lamellar keratitis.

Case presentation
A 26 year old man developed bilateral diffuse lamellar keratitis (DLK) following myopic LASIK. The residual refractive error was +0.5D OD and +0.25D OS at the end of the first week. The sterile infiltrates resolved over a period of 4–6 weeks on topical steroid therapy. A progressive hyperopic shift was noted in the right eye with an error +4.25Dsph/+0.25Dcyl 20 at the final follow up 6 months post surgery.

Conclusion
Diffuse lamellar keratitis after LASIK may be associated with a significant hyperopic shift.
Water quality and immatures of the M and S forms of Anopheles gambiae s.s. and An. arabiensis in a Malian village
Authors: Edillo Frances E , Tripét Frederic , Touré Yeya T , Lanzaro Gregory C , Dolo Guimogo , Taylor Charles E 
Published: April 2006

Abstract

Introduction
The associations between the immatures of Anopheles gambiae s.s. (Diptera: Culicidae), its M and S forms, and Anopheles arabiensis among and within larval breeding habitats in Banambani, Mali were investigated under varying conditions of water quality and rainfall. The intent was to elucidate on niche partitioning of these taxa.

Methods
Immatures of An. arabiensis, An. gambiae s.s., and its M and S forms were sampled every alternate day for a month in mid-rainy season from three sampling sites in each of the larval breeding habitats (rock pools, swamp, and puddles). Water quality was characterized by alkalinity, conductivity, dissolved oxygen (D.O.), nitrate, orthophosphate, pH, temperature, total dissolved solids (TDS), and turbidity. A type 3 analysis of the GENMOD model was used to examine the associations between the proportional frequencies of young (first and second instar larvae) and old (third and fourth instar larvae and pupae) or total immatures of species or forms among sampling sites within and among larval breeding habitats during a category of rainfall as influenced by water quality.

Results
Of the 4,174 immatures sampled, 1,300 were molecularly identified to species and forms. Significant association between the proportional frequencies of young larvae of An. arabiensis, An. gambiae s.s., its M and S forms was found among sampling sites within habitats but not among larval breeding habitats. The proportional frequencies of young larvae of M and S forms varied daily perhaps due to recruitment, mortality, and dispersal within habitats. Conductivity and TDS had significant effects when the proportional frequencies of young larvae of M and S forms among sampling sites within habitats were significantly associated. Alkalinity, D.O., orthophosphate, pH, nitrate, temperature and turbidity had no effects on niche partitioning of species and forms among sampling sites within habitats. Rainfall did not affect the frequencies of these immatures.

Conclusion
Conductivity and TDS have significant effects on niche partitioning of young larvae of M and S forms among sampling sites within habitats in Banambani, Mali.
Raising the Bar for the Training of College Teachers: An Interview with Victor Benassi
Authors: Wimer David J. 
Published: April 2006

Victor A. Benassi earned his bachelor's degree from California State College and his PhD in psychology from the City University of New York. After working in the Department of Psychology at California State University at Long Beach, he moved to the University of New Hampshire (UNH) in 1982. He is currently Professor of Psychology and Professor of College Teaching. He has been one of the leaders of his department's long-standing Preparing Future Faculty (PFF) component of the PhD program. In 2003, this program received recognition from the American Psychological Association's (APA) Board of Educational Affairs for its innovation and creativity. He has also played a part, along with several colleagues, in facilitating the development of UNH's academic program in college teaching. UNH received the 2002 Theodore M. Hesburgh Award for Faculty Development to Enhance Undergraduate Teaching (Certificate of Excellence) in recognition of this program. Benassi has received several awards within UNH for his scholarship and teaching and received the Charles L. Brewer Distinguished Teaching of Psychology Award from the American Psychological Foundation in 2003. His research has focused on judgment and belief, and he has published articles on belief in alleged paranormal phenomena, illusory control, and judgment of contingency. He also maintains an ongoing program of research with a colleague on teaching and learning at the college level. David J. Wimer is the past chair of the Society for the Teaching of Psychology's (STP) Graduate Student Teaching Association. In 1998 he received his bachelor's degree in psychology from Ithaca College in Ithaca, New York. While at Ithaca, he had the pleasure of working on Barney Beins's psychology of humor research team. He received his MA in social psychology from Miami University in Oxford, Ohio and is currently working toward a PhD in counseling psychology from the University of Akron in Akron, Ohio, where he works with Loreto Prieto.
Multiple Quantitative Trait Loci Modify Cochlear Hair Cell Degeneration in the Beethoven (Tmc1Bth) Mouse Model of Progressive Hearing Loss DFNA36
Authors: Noguchi Yoshihiro , Kurima Kiyoto , Makishima Tomoko , de Angelis Martin Hrabé , Fuchs Helmut , Frolenkov Gregory , Kitamura Ken , Griffith Andrew J 
Published: April 2006

Abstract
Dominant mutations of transmembrane channel-like gene 1 (TMC1) cause progressive sensorineural hearing loss in humans and Beethoven (Tmc1Bth/+) mice. Here we show that Tmc1Bth/+ mice on a C3HeB/FeJ strain background have selective degeneration of inner hair cells while outer hair cells remain structurally and functionally intact. Inner hair cells primarily function as afferent sensory cells, whereas outer hair cells are electromotile amplifiers of auditory stimuli that can be functionally assessed by distortion product otoacoustic emission (DPOAE) analysis. When C3H-Tmc1Bth/Bth is crossed with either C57BL/6J or DBA/2J wild-type mice, F1 hybrid Tmc1Bth/+ progeny have increased hearing loss associated with increased degeneration of outer hair cells and diminution of DPOAE amplitudes but no difference in degeneration of inner hair cells. We mapped at least one quantitative trait locus (QTL), Tmc1m1, for DPOAE amplitude on chromosome 2 in [(C/B)F1 × C]N2-Tmc1Bth/+ backcross progeny, and three other QTL on chromosomes 11 (Tmc1m2), 12 (Tmc1m3), and 5 (Tmc1m4) in [(C/D)F1 × C]N2-Tmc1Bth/+ progeny. The polygenic basis of outer hair cell degeneration in Beethoven mice provides a model system for the dissection of common, complex hearing loss phenotypes, such as presbycusis, that involve outer hair cell degeneration in humans.
Evolution and Expression of Homeologous Loci in Tragopogon miscellus (Asteraceae), a Recent and Reciprocally Formed Allopolyploid
Authors: Tate Jennifer A , Ni Zhongfu , Scheen Anne-Cathrine , Koh Jin , Gilbert Candace A , Lefkowitz David , Chen Z Jeffrey , Soltis Pamela S , Soltis Douglas E 
Published: April 2006

Abstract
On both recent and ancient time scales, polyploidy (genome doubling) has been a significant evolutionary force in plants. Here, we examined multiple individuals from reciprocally formed populations of Tragopogon miscellus, an allotetraploid that formed repeatedly within the last 80 years from the diploids T. dubius and T. pratensis. Using cDNA–AFLPs followed by genomic and cDNA cleaved amplified polymorphic sequence (CAPS) analyses, we found differences in the evolution and expression of homeologous loci in T. miscellus. Fragment variation within T. miscellus, possibly attributable to reciprocal formation, comprised 0.6% of the cDNA–AFLP bands. Genomic and cDNA CAPS analyses of 10 candidate genes revealed that only one “transcript-derived fragment” (TDF44) showed differential expression of parental homeologs in T. miscellus; the T. pratensis homeolog was preferentially expressed by most polyploids in both populations. Most of the cDNA–AFLP polymorphisms apparently resulted from loss of parental fragments in the polyploids. Importantly, changes at the genomic level have occurred stochastically among individuals within the independently formed populations. Synthetic F1 hybrids between putative diploid progenitors are additive of their parental genomes, suggesting that polyploidization rather than hybridization induces genomic changes in Tragopogon.
Networked Control Systems
Authors: Liu Kun , Selivanov Anton , Fridman Emilia 
Published: March 2024

AbstractNetworked control systems (NCSs) are spatially distributed systems in which the sensors, actuators, and controllers are connected through a shared communication network. The advantages of the network architectures include reduced system wiring, plug and play devices, increased system agility, and ease of system diagnosis and maintenance. Meanwhile, the presence of a communication network in a control loop induces many imperfections. Therefore, the analysis and synthesis of NCSs have received considerable attention in the last two decades. In this article, we review fundamental communication imperfections in NCSs and the main approaches to the modeling of NCSs. Then, recent results on time‐delay approach to event‐triggered control are recalled. The article highlights time‐delay approach developed to modeling, analysis and synthesis of NCSs, under communication constraints, with a particular focus on Round‐Robin, Try‐once‐discard, and stochastic protocols. The time‐delay approach allows communication delays to be larger than the sampling intervals in the presence of scheduling protocols. Moreover, some results on networked control of distributed parameter systems are introduced. Finally, some open problems are briefly addressed.
Histatin 5‐Inspired Short‐Chain Peptides Selectively Combating Pathogenic Fungi with Multifaceted Mechanisms
Authors: Lu Guojun , Ju Xiaoyan , Zhu Meng , Ou Jinzhao , Xu Dandan , Li Kejia , Jiang Wei , Wan Chenxiao , Tian Ye , Niu Zhongwei 
Published: March 2024

AbstractShort‐chain antifungal peptides (AFPs) inspired by histatin 5 have been designed to address the problem of antifungal drug resistance. These AFPs demonstrate remarkable antifungal activity, with a minimal inhibitory concentration as low as 2 µg mL−1. Notably, these AFPs display a strong preference for targeting fungi rather than bacteria and mammalian cells. This is achieved by binding the histidine‐rich domains of the AFPs to the Ssa1/2 proteins in the fungal cell wall, as well as the reduced membrane‐disrupting activity due to their low amphiphilicity. These peptides disrupt the nucleus and mitochondria once inside the cells, leading to reactive oxygen species production and cell damage. In a mouse model of vulvovaginal candidiasis, the AFPs demonstrate not only antifungal activity, but also promote the growth of beneficial Lactobacillus spp. This research provides valuable insights for the development of fungus‐specific AFPs and offers a promising strategy for the treatment of fungal infectious diseases.
Reversal of Chemoresistance via Staged Liberation of Chemodrug and siRNA in Hierarchical Response to ROS Gradient
Authors: Dang Juanjuan , Li Yongjuan , Yan Jing , Wu Jianhua , Cai Kaimin , Yin Lichen , Zhou Zhuchao 
Published: March 2024

AbstractP‐glycoprotein (P‐gp)‐mediated multidrug resistance (MDR) often leads to the failure of antitumor chemotherapy, and codelivery of chemodrug with P‐gp siRNA (siP‐gp) represents a promising approach for treating chemoresistant tumors. To maximize the antitumor efficacy, it is desired that the chemodrug be latently released upon completion of siP‐gp‐mediated gene silencing, which however, largely remains an unmet demand. Herein, core–shell nanocomplexes (NCs) are developed to overcome MDR via staged liberation of siP‐gp and chemodrug (doxorubicin, Dox) in hierarchical response to reactive oxygen species (ROS) concentration gradients. The NCs are constructed from mesoporous silica nanoparticles (MSNs) surface‐decorated with cRGD‐modified, PEGylated, ditellurium‐crosslinked polyethylenimine (RPPT), wherein thioketal‐linked dimeric doxorubicin (TK‐Dox2) and photosensitizer are coencapsulated inside MSNs while siP‐gp is embedded in the RPPT polymeric layer. RPPT with ultrahigh ROS‐sensitivity can be efficiently degraded by the low‐concentration ROS inside cancer cells to trigger siP‐gp release. Upon siP‐gp‐mediated gene silencing and MDR reversal, light irradiation is performed to generate high‐concentration, lethal amount of ROS, which cleaves thioketal with low ROS‐sensitivity to liberate the monomeric Dox. Such a latent release profile greatly enhances Dox accumulation in Dox‐resistant cancer cells (MCF‐7/ADR) in vitro and in vivo, which cooperates with the generated ROS to efficiently eradicate MCF‐7/ADR xenograft tumors.
Single‐Atom Cu Nanozyme‐Loaded Bone Scaffolds for Ferroptosis‐Synergized Mild Photothermal Therapy in Osteosarcoma Treatment
Authors: Yan Zuyun , Wu Xin , Tan Wei , Yan Jinpeng , Zhou Jun , Chen Shijie , Miao Jinglei , Cheng Jun , Shuai Cijun , Deng Youwen 
Published: March 2024

AbstractThe rapid multiplication of residual tumor cells and poor reconstruction quality of new bone are considered the major challenges in the postoperative treatment of osteosarcoma. It is a promising candidate for composite bone scaffold which combines photothermal therapy (PTT) and bone regeneration induction for the local treatment of osteosarcoma. However, it is inevitable to damage the normal tissues around the tumor due to the hyperthermia of PTT, while mild heat therapy shows a limited effect on antitumor treatment as the damage can be easily repaired by stress‐induced heat shock proteins (HSP). This study reports a new type of single‐atom Cu nanozyme‐loaded bone scaffolds, which exhibit exceptional photothermal conversion properties as well as peroxidase and glutathione oxidase mimicking activities in vitro experiments. This leads to lipid peroxidation (LPO) and reactive oxygen species (ROS) upregulation, ultimately causing ferroptosis. The accumulation of LPO and ROS also contributes to HSP70 inactivation, maximizing PTT efficiency against tumors at an appropriate therapeutic temperature and minimizing the damage to surrounding normal tissues. Further, the bone scaffold promotes bone regeneration via a continuous release of bioactive ions (Ca2+, P5+, Si4+, and Cu2+). The results of in vivo experiments reveal that scaffolds inhibit tumor growth and promote bone repair.