bluuebunny/crossref_metadata_2025_split huggingface dataset:
Big data analytics-artificial intelligence and sustainable performance through green supply chain practices in manufacturing firms of a developing country
Authors: Rashid Aamir , Baloch Neelam , Rasheed Rizwana , Ngah Abdul Hafaz 
Published: March 2024

Purpose
This study aims to examine the role of big data analytics (BDA) powered by artificial intelligence (AI) in improving sustainable performance (SP) through green supply chain collaboration (GSCC), sustainable manufacturing (SM) and environmental process integration (EPI).

Design/methodology/approach
Data was collected from 249 supply chain professionals working at various manufacturing firms, and hypotheses were tested through a quantitative method using PLS-SEM with the help of SmartPLS version 4 to validate the measurement model.

Findings
This study identified that BDA-AI significantly and positively affects GSCC, SM and EPI. Similarly, the results showed that GSCC significantly and positively affects SP. At the same time, SM and EPI have an insignificant effect on SP. The GSCC found a significant relationship between BDA-AI and SP for mediation. However, SM and environmental performance integration did not mediate the relationship between BDA and AI and SP.

Originality/value
This research evaluated a second-order model and tested SP in conjunction with the dynamic capability theory in the manufacturing industry of Pakistan. Therefore, this research could be beneficial for researchers, manufacturers and policymakers to attain sustainable goals by implementing the BDA-AI in the supply chain.
Reproductive biology in Gomphichis valida Rchb. f. (Orchidaceae: Orchidoideae, Cranichidinae): Generalist pollination in a high‐Andean terrestrial orchid with long‐lived flowers
Authors: Calderon‐Quispe Fernando H. , Bustos Singer Rodrigo 
Published: March 2024

AbstractFloral features, the pollination process, the breeding system, and fruiting success are documented in the Andean terrestrial orchid Gomphichis valida. Studies were performed at the Department of Ancash, Peru, at ca. 4250 m a.s.l., from June to November 2022. The breeding system was studied through controlled pollinations in plants excluded from pollinators (bagged). Natural pollination was studied in the field and through photos and videos. The flowers are nectariferous and non‐protandrous and present the longest lifespan reported so far for a neotropical terrestrial orchid (53–80 days). This species is pollinator dependent (unable to set fruit and seed without the agency of pollinators) and self‐compatible. The observed pollinators belong to three functional groups that appeared successively (in order of appearance): hummingbirds (Chalcostigma stanleyi), bumblebees (Bombus coccineus and Bombus rubicundus), and solitary Halictidae bees (Augochlorella sp.). All recorded pollinators probe the flowers for nectar. The pollinaria adhere to the bee mouthparts and onto the lateral side of the hummingbird bill. Bumblebees were the most frequent and efficient functional group (up to 62.07% of the observed pollination events), followed by Halictidae (31.03%) and hummingbirds (6.90%). Natural fruiting success is high (66.66%–94.49%). Such high natural fruiting success is unexpected at high altitudes, but it is likely explained by a combination of factors, including the long floral lifespan, nectar secretion, and self‐compatibility. This is the first report of hummingbirds as pollinators of Cranichidinae orchids, and G. valida is, to the best of our knowledge, a neotropical orchidoid orchid with the most generalist pollination biology recorded so far.
Do Digital Technologies Enable Firms that Prioritize Sustainability Goals to Innovate? Empirical Evidence from Established UK Micro‐businesses
Authors: Jibril Halima , Kesidou Effie , Roper Stephen 
Published: March 2024

AbstractThis paper examines the importance of sustainability within firms’ strategic goals and its links with innovation in the context of micro‐businesses. Micro‐businesses provide an appropriate context for investigating this relationship because, while they tend to prioritize social and environmental goals, they are also more likely to confront resource constraints that can restrict their capability to innovate. Building on goal‐setting theory and the resource‐based view (RBV) of the firm, we explore under what conditions established micro‐businesses that prioritize sustainability goals are more likely to innovate. Using novel survey data on 4649 established micro‐businesses in the UK, we examine the enabling role of digital technologies. Our results suggest that owner‐managers who prioritize sustainability goals are significantly more likely to generate new product and process innovations. Moreover, we find that this effect is stronger when micro‐businesses adopt digital technologies. Digital technologies enhance the capabilities of micro‐businesses, strengthening the connection between sustainability goals and product and process innovation.
Electrofermentation increases concentration of poly γ‐glutamic acid in Bacillus subtilis biofilms
Authors: Adilkhanova Alina , Ormantayeva Anar , Kaziullayeva Aisholpan , Olaifa Kayode , Eghtesadi Neda , Abbas Azza H. , Calvio Cinzia , Pham Tri T. , Ajunwa Obinna M. , Marsili Enrico 
Published: March 2024

AbstractFluctuations in redox conditions in bioprocesses can alter the end‐products, reduce their concentration, and lengthen the process time. Electrofermentation enables rapid metabolic modulation of biosynthesis and allows control of redox imbalances in biofilm‐based fermentation processes. In this study, electrofermentation is used to boost the production of the bacterial biopolymer poly‐γ‐glutamic acid (γ‐PGA) from Bacillus subtilis ATCC 6051. When compared to control experiments (3.3 ± 0.99 g L−1), the application of an electrode potential E = 0.4 V versus Ag/AgCl results in a more than two‐fold increase in the production of γ‐PGA (9.13 ± 1.4 g L−1). Using an engineered B. subtilis strain, in which γ‐PGA production is driven by isopropyl β‐d‐1‐thiogalactopyranoside, electrofermentation improves polymer concentrations from 15.4 ± 1.5 to 23.1 ± 1.6 versus g L−1. These results confirm that electrofermentation conditions can be adopted to increase the concentration of γ‐PGA and perhaps other extracellular biopolymers in industrial strains.
Misattribution prevents learning
Authors: Hoel Jessica B. , Michelson Hope , Norton Ben , Manyong Victor 
Published: March 2024

AbstractIn many markets, consumers believe things about products that are not true. We study how incorrect beliefs about product quality can persist even after a consumer has used a product many times. We explore the example of fertilizer in East Africa. Farmers believe much local fertilizer is counterfeit or adulterated; however, multiple studies have established that nearly all fertilizer in the area is good quality. We develop a learning model to explain how these incorrect beliefs persist. We show that when the distributions of outcomes using good and bad quality products overlap, agents can misattribute bad luck or bad management to bad quality. Our learning model and its simulations show that the presence of misattribution inhibits learning about quality and that goods like fertilizer with unobservable quality that are inputs into production processes characterized by stochasticity should be thought of as credence goods, not experience goods. Our results suggest that policy makers should pursue quality assurance programs for products that are vulnerable to misattribution.
Validation of the Kimberley Cognitive Assessment (KICA‐Cog) for Torres Strait Islander Peoples
Authors: Russell Sarah G. , Quigley Rachel , Thompson Fintan , Sagigi Betty , Miller Gavin , LoGiudice Dina , Smith Kate , Flicker Leon , Pachana Nancy A. , Kordick Sarah , Strivens Edward 
Published: March 2024

AbstractObjectivesThe aim of this study was to validate the Kimberley Indigenous Cognitive Assessment—Cognitive Component (KICA‐Cog) adapted for dementia screening in Torres Strait Islander Peoples.MethodsData were obtained from a broader dementia prevalence study completed in the Torres Strait and Northern Peninsula Area between 2015 and 2018. Modifications were made to items from the original KICA‐Cog to ensure they were culturally appropriate for the Torres Strait. All participants completed a KICA‐Cog and had a comprehensive dementia assessment with a geriatrician experienced in cross‐cultural assessment.ResultsA total of 255 Torres Strait residents aged 45 years and over completed a KICA‐Cog and underwent geriatric assessment. The adapted KICA‐Cog showed good validity for dementia diagnosis with a cut point of 33/34 associated with a sensitivity of 81% and specificity of 92% with an area under the ROC curve of 0.91.ConclusionsThe KICA‐Cog, when modified for the Torres Strait, is a valid cognitive screening tool for dementia. Caution is required when interpreting test scores, as the adapted KICA‐Cog had slightly lower sensitivity (ability to detect people with dementia) than the original KICA‐Cog. As with all short cognitive tests, individuals with a low KICA‐Cog scores should undergo further medical investigations before a dementia diagnosis is considered.
Exploring the inequalities of women with learning disabilities deciding to attend and then accessing cervical and breast cancer screening, using the Social Ecological Model
Authors: Sykes Kate , McGeechan Grant J. , Giles Emma L. 
Published: March 2024

AbstractBackgroundWomen with learning disabilities are less likely to access cervical and breast cancer screening when compared to the general population. The Social Ecological Model (SEM) was used to examine the inequalities faced by women with learning disabilities in accessing cervical and breast cancer screening in England, UK.MethodsThe findings from a qualitative systematic review and a Q methodology study were triangulated. Framework analysis, in line with the SEM, was used to develop an integrated set of findings.FindingsWomen with learning disabilities may lack knowledge of cancer symptoms, and cancer screening, as well as being scared about the process and getting the results. The attitudes of family and paid carers towards screening may influence women with learning disabilities' decisions as to whether screening is seen as favourable; support and training may ensure unbiased perspectives. Barriers were also associated with how cancer screening programmes are designed, such as postal invitations which assumes an ability to read. In addition, screening staff need to be aware of the general needs of people with learning disabilities, such as the benefits of easy‐to‐read documents. Lastly, multidisciplinary working is required so reasonable adjustments can be embedded into cancer screening pathways.ConclusionThis article highlights multiple methods to reduce the inequalities faced by women with learning disabilities, which can be achieved through reasonable adjustments. Embedding reasonable adjustments can support women with learning disabilities in making an informed decision and accessing screening if they choose to. This may result in women with learning disabilities getting a timely cancer diagnosis.
Metabolic trade‐offs in childhood: Exploring the relationship between language development and body growth
Authors: Bouton Sophie , Chevallier Coralie , Cissé Aminata Hallimat , Heude Barbara , Jacquet Pierre O. 
Published: March 2024

AbstractDuring human childhood, brain development and body growth compete for limited metabolic resources, resulting in a trade‐off where energy allocated to brain development can decrease as body growth accelerates. This preregistered study explores the relationship between language skills, serving as a proxy for brain development, and body mass index at three distinct developmental stages, representing different phases of body growth. Longitudinal data from 2002 children in the EDEN mother‐child cohort were analyzed using structural equation modeling. Our findings reveal a compelling pattern of associations: girls with a delayed adiposity rebound, signaling slower growth rate, demonstrated better language proficiency at ages 5–6. Importantly, this correlation appears to be specific to language skills and does not extend to nonverbal cognitive abilities. Exploratory analyses show that early environmental factors contributing to enhanced cognitive development, such as higher parental socio‐economic status and increased cognitive stimulation, are positively associated with both language skills and the timing of adiposity rebound in girls. Overall, our findings lend support to the existence of an energy allocation trade‐off mechanism that appears to prioritize language function over body growth investment in girls.Research Highlights
The high energy demand of neurocognitive development leads to a trade‐off in human children between brain growth and other biological functions, including body growth.
Previous studies indicate that around age 5, when the brain energy consumption peaks, children typically experience a decrease in body mass known as ‘adiposity rebound’.
A delayed adiposity rebound, indicating slower growth may be associated with enhanced language abilities in children.
Our preregistered study confirms this correlation in girls and further associates early cognitive stimulation with improved language skills and delayed adiposity rebound time.
Aldosterone synthase inhibitor (BI 690517) therapy for people with diabetes and albuminuric chronic kidney disease: A multicentre, randomized, double‐blind, placebo‐controlled, Phase I trial
Authors: Bornstein Stefan R. , de Zeeuw Dick , Heerspink Hiddo J. L. , Schulze Friedrich , Cronin Lisa , Wenz Arne , Tuttle Katherine R. , Hadjadj Samy , Rossing Peter 
Published: March 2024

AbstractAimThis Phase I study evaluated the safety and early efficacy of an aldosterone synthase inhibitor (BI 690517) in people with diabetes and albuminuric chronic kidney disease.MethodsDouble‐blind, placebo‐controlled study (NCT03165240) at 40 sites across Europe. Eligible participants [estimated glomerular filtration rate ≥20 and <75 ml/min/1.73 m2; urine albumin/creatinine ratio (UACR) ≥200 and <3500 mg/g] were randomized 6:1 to receive once‐daily oral BI 690517 3, 10 or 40 mg, or eplerenone 25‐50 mg, or placebo, for 28 days. The primary endpoint was the proportion of participants with drug‐related adverse events (AEs). Secondary endpoints included changes from baseline in the UACR.ResultsFifty‐eight participants were randomized and treated from 27 November 2017 to 16 April 2020 (BI 690517: 3 mg, n = 18; 10 mg, n = 13; 40 mg, n = 14; eplerenone, n = 4; placebo, n = 9) for 28 days. Eight (13.8%) participants experienced drug‐related AEs [BI 690517: 3 mg (two of 18); 10 mg (four of 13); 40 mg (two of 14)], most frequently constipation [10 mg (one of 13); 40 mg (one of 14)] and hyperkalaemia [3 mg (one of 18); 10 mg (one of 13)]. Most AEs were mild to moderate; one participant experienced severe hyperkalaemia (serum potassium 6.9 mmol/L; BI 690517 10 mg). UACR responses [≥20% decrease from baseline (first morning void urine) after 28 days] were observed for 80.0% receiving BI 690517 40 mg (eight of 10) versus 37.5% receiving placebo (three of eight). Aldosterone levels were suppressed by BI 690517, but not eplerenone or placebo.ConclusionsBI 690517 was generally well tolerated, reduced plasma aldosterone and may decrease albuminuria in participants with diabetes and albuminuric chronic kidney disease.
Disrupting direct inputs from the dorsal subiculum to the granular retrosplenial cortex impairs flexible spatial memory in the rat
Authors: Yanakieva Steliana , Frost Bethany E. , Amin Eman , Nelson Andrew J. D. , Aggleton John P. 
Published: March 2024

AbstractIn a changing environment, animals must process spatial signals in a flexible manner. The rat hippocampal formation projects directly upon the retrosplenial cortex, with most inputs arising from the dorsal subiculum and terminating in the granular retrosplenial cortex (area 29). The present study examined whether these same projections are required for spatial working memory and what happens when available spatial cues are altered. Consequently, injections of iDREADDs were made into the dorsal subiculum of rats. In a separate control group, GFP‐expressing adeno‐associated virus was injected into the dorsal subiculum. Both groups received intracerebral infusions within the retrosplenial cortex of clozapine, which in the iDREADDs rats should selectively disrupt the subiculum to retrosplenial projections. When tested on reinforced T‐maze alternation, disruption of the subiculum to retrosplenial projections had no evident effect on the performance of those alternation trials when all spatial‐cue types remained present and unchanged. However, the same iDREADDs manipulation impaired performance on all three alternation conditions when there was a conflict or selective removal of spatial cues. These findings reveal how the direct projections from the dorsal subiculum to the retrosplenial cortex support the flexible integration of different spatial cue types, helping the animal to adopt the spatial strategy that best meets current environmental demands.
Clinical outcomes among initial survivors of cryptogenic new‐onset refractory status epilepsy (NORSE)
Authors: Costello Daniel J. , Matthews Elizabeth , Aurangzeb Sidra , Doran Elisabeth , Stack Jessica , Wesselingh Robb , Dugan Patricia , Choi Hyunmi , Depondt Chantal , Devinsky Orrin , Doherty Colin , Kwan Patrick , Monif Mastura , O'Brien Terence J. , Sen Arjune , Gaspard Nicolas 
Published: March 2024

AbstractObjectiveNew‐onset refractory status epilepticus (NORSE) is a rare but severe clinical syndrome. Despite rigorous evaluation, the underlying cause is unknown in 30%–50% of patients and treatment strategies are largely empirical. The aim of this study was to describe clinical outcomes in a cohort of well‐phenotyped, thoroughly investigated patients who survived the initial phase of cryptogenic NORSE managed in specialist centers.MethodsWell‐characterized cases of cryptogenic NORSE were identified through the EPIGEN and Critical Care EEG Monitoring Research Consortia (CCEMRC) during the period 2005–2019. Treating epileptologists reported on post‐NORSE survival rates and sequelae in patients after discharge from hospital. Among survivors >6 months post‐discharge, we report the rates and severity of active epilepsy, global disability, vocational, and global cognitive and mental health outcomes. We attempt to identify determinants of outcome.ResultsAmong 48 patients who survived the acute phase of NORSE to the point of discharge from hospital, 9 had died at last follow‐up, of whom 7 died within 6 months of discharge from the tertiary care center. The remaining 39 patients had high rates of active epilepsy as well as vocational, cognitive, and psychiatric comorbidities. The epilepsy was usually multifocal and typically drug resistant. Only a minority of patients had a good functional outcome. Therapeutic interventions were heterogenous during the acute phase of the illness. There was no clear relationship between the nature of treatment and clinical outcomes.SignificanceAmong survivors of cryptogenic NORSE, longer‐term outcomes in most patients were life altering and often catastrophic. Treatment remains empirical and variable. There is a pressing need to understand the etiology of cryptogenic NORSE and to develop tailored treatment strategies.
Microclimate modulation: An overlooked mechanism influencing the impact of plant diversity on ecosystem functioning
Authors: Beugnon Rémy , Le Guyader Nolwenn , Milcu Alexandru , Lenoir Jonathan , Puissant Jérémy , Morin Xavier , Hättenschwiler Stephan 
Published: March 2024

AbstractChanges in climate and biodiversity are widely recognized as primary global change drivers of ecosystem structure and functioning, also affecting ecosystem services provided to human populations. Increasing plant diversity not only enhances ecosystem functioning and stability but also mitigates climate change effects and buffers extreme weather conditions, yet the underlying mechanisms remain largely unclear. Recent studies have shown that plant diversity can mitigate climate change (e.g. reduce temperature fluctuations or drought through microclimatic effects) in different compartments of the focal ecosystem, which as such may contribute to the effect of plant diversity on ecosystem properties and functioning. However, these potential plant diversity‐induced microclimate effects are not sufficiently understood. Here, we explored the consequences of climate modulation through microclimate modification by plant diversity for ecosystem functioning as a potential mechanism contributing to the widely documented biodiversity–ecosystem functioning (BEF) relationships, using a combination of theoretical and simulation approaches. We focused on a diverse set of response variables at various levels of integration ranging from ecosystem‐level carbon exchange to soil enzyme activity, including population dynamics and the activity of specific organisms. Here, we demonstrated that a vegetation layer composed of many plant species has the potential to influence ecosystem functioning and stability through the modification of microclimatic conditions, thus mitigating the negative impacts of climate extremes on ecosystem functioning. Integrating microclimatic processes (e.g. temperature, humidity and light modulation) as a mechanism contributing to the BEF relationships is a promising avenue to improve our understanding of the effects of climate change on ecosystem functioning and to better predict future ecosystem structure, functioning and services. In addition, microclimate management and monitoring should be seen as a potential tool by practitioners to adapt ecosystems to climate change.
Long‐term smell loss experiences after COVID‐19: A qualitative study
Authors: Alkanat Hafize Özdemir , Arslan Selda 
Published: March 2024

AbstractObjectivesSudden smell loss is one of the early symptoms of COVID‐19. Although it is stated that the loss of smell and taste following COVID‐19 improves within a few weeks, there are also cases that do not improve for a long time. The aim of this study is to reveal long‐term smell loss experiences after COVID‐19.MethodsA qualitative approach was adopted. We conducted semistructured interviews with 11 participants who had smell loss for at least 3 months. Interviews were recorded, transcribed and evaluated using a thematic analysis for qualitative data.ResultsNutrition and appetite, personal hygiene, threats to safety and emotional changes were the main themes created by the authors and were the areas where participant expressions focused. The participants used oral/nasal corticosteroid therapy for smell loss and received short‐term olfactory training, but could not find a solution.ConclusionsLong‐term smell loss problems, which were neglected during the pandemic period, should be carefully evaluated due to their negative effects. Understanding and focusing on the negative effects of loss of smell may contribute to the solution of long‐term smell loss problems.Patient and Public ContributionEleven participants who experienced long‐term loss of smell following COVID‐19 contributed to the study. They enriched the study by describing the effects of their experiences. There was no other participation or contribution from the public to the research.
CORPORATE EARNINGS ANNOUNCEMENTS AND ECONOMIC ACTIVITY
Authors: Miescu Mirela S. , Mumtaz Haroon 
Published: March 2024

AbstractAre corporate earnings (CE) announcements important for economic activity? We address this question using a novel identification method that combines the valuable information from CE announcements with the heteroscedasticity of shocks experienced on these particular days. Our results demonstrate that CE announcements have a significant impact on the macroeconomy, exhibiting dynamics similar to traditional financial disruptions. We establish that CE announcements' shocks can be classified as financial shocks, highlighting their critical role in the financial system.