bluuebunny/crossref_metadata_2025_split huggingface dataset:
Titin is a nucleolar protein in neurons
Authors: George Lynn , Cameron BreAnna , Torres-Hernandez Lauryn , Montague Virginia , Lewis Karen , Smith Heidi , Fox James , Guo Xueshui , Kalb Robert G. 
Published: March 2024

Abstract
Titin is the largest protein produced by living cells and its function as a molecular spring in striated muscle is well characterized (1, 2). Here we demonstrate that titin isoforms in the same size range as found in muscle are prominent neuronal proteins in both the central and peripheral nervous systems, including motor neurons in the spinal cord and brain. Within these neurons, titin localizes to the dense fibrillar component of the nucleolus, the site of ribosomal RNA biogenesis and modification, and a critical site of dysfunction in neurodegenerative disease (3-5). Additionally, we show that the levels of both titin mRNA and protein are altered in the spinal cord of SOD1G93A mice, a commonly used model of amyotrophic lateral sclerosis, indicating that titin mediated nucleolar events may in fact contribute to the pathobiology of disease.
Excitonic signatures of ferroelectric order in parallel-stacked MoS2
Authors: Deb Swarup , Krause Johannes , Kempf Michael , Schwartz Rico , Korn Tobias , Watanabe Kenji , Taniguchi Takashi , Junior Paulo E. Faria , Fabian Jaroslav 
Published: March 2024

Abstract
Interfacial ferroelectricity is a phenomenon arising in a plethora of parallel-stacked layered materials,1-11 in which out-of-plane ferroelectric order is switched by in-plane sliding of adjacent layers.4 Unlike conventional ferroelectrics, interfacial ferroelectricity is stable against doping,7 potentially enabling next-generation devices with storage and computational capabilities.12 However, the field has been limited to indirect sensing or visualizing the ferroelectricity in basic bilayer units employing surface-sensitive probes. In the case of transition metal dichalcogenides, this leaves a void of in-depth knowledge about the influence of ferroelectric order on their intrinsic valley and excitonic properties. Here, we report direct far-field probing of ferroelectricity in few-layer 3R-MoS2 using reflectance contrast spectroscopy. Contrary to a simple electrostatic perception, the intralayer excitons with strictly in-plane dipole orientation are sensitive to out-of-plane ferroelectric ordering. On the other hand, despite possessing an out-of-plane electric dipole component,13 layer-hybridized momentum-indirect excitons remain decoupled from such ordering. Ab initio calculations elucidate the microscopic origin of the correspondence between ferroelectric order and optical response. Using a field-effect device, we demonstrate room temperature control and optical readout of multi-state polarization and its hysteretic switching. Time-resolved Kerr ellipticity measured in different ferroelectric domains reveals a direct correspondence between spin-valley dynamics and ferroelectric order.
Examining the Influence of Shift length on Nurse Fatigue, Patient Care, Quality of Life, and Work-Life Dynamics in a Tertiary Hospital in Oman: Comparative Study
Authors: Rabaani Eman Al , Yahyaei Asma Al , Alkasbi Rahaf , Alhashmi Yumna , Hatmi Ibrahim Al 
Published: March 2024

Abstract
This study investigates a comparative analysis of the perceptions of nurses engaged in 8-hour and 12-hour shifts, exploring various dimensions of their professional and personal lives. Conducted in a tertiary hospital in Muscat, Oman, the research investigates the potential impact of shift length on factors such as fatigue levels, quality of life, satisfaction, and safety incidents. While revealing nuanced insights into the advantages and drawbacks of each shift system, the study emphasizes caution in generalizing findings to other medical institutions. Methodological limitations, including the singular hospital focus and the short-term nature of the assessment after the 12-hour shift implementation, are acknowledged. The study calls for future research to expand these insights to diverse contexts and employ longitudinal approaches. Implications for nursing practice underscore the need for informed decision-making by management, considering factors such as nurse well-being, patient safety, and continuity of care. The study contributes valuable insights to the ongoing discourse on nursing shift lengths, emphasizing considerations for both research and practical application.
Schistosoma japonicum complex: relatedness of the parasites and relatedness of its intermediate hosts in evolution
Authors: Nelwan Martin 
Published: March 2024

Abstract
Purpose
In this research, I report the relationship between S. ovuncatum, S. sinensium, S. japonicum, S. mekongi, and S. malayensis. Additionally, I also report the relatedness between five species of Oncomelania and Neotricula aperta, Robertsiella spp, and Tricula spp. Furthermore, I describe the formation of the genus Oncomelania from its predecessor forms.
Principal Results:
The results of nucleotide BLAST showed that S. ovuncatum shared 99.69% identity with S. sinensium, 98.68% identity with S. mekongi, 97.98% identity with S. malayensis, and 97.85% identity with S. japonicum. All E-values are smaller than 0.01. The tree-view slanted cladogram showed that S. sinensium is a sister to S. ovuncatum. It split into S. japonicum. Schistosoma japonicum splits into S. mekongi and S. malayensis. The results also showed that Oncomelania robertsoni shared 86.12% identity with Neotricula aperta, 85.88% identity with Robertsiella spp., and 85.28% identity with Tricula bollingi. The tree-view slanted cladogram showed that Tricula spp. split into N. aperta and Robertsiella spp. This study showed that Oncomelania emerged from its predecessor forms.
Conclusions
Nucleotide BLAST results showed that S. ovuncatum is close to S. sinensium. Schistosoma sinensium split into S. japonicum, S. mekongi, and S. malayensis. Oncomelania robertsoni was closer to N. aperta than to Robertsiella spp. and Tricula spp. (Tricula bollingi). Oncomelania species emerged from their predecessor forms.
Correlating Measures of Hierarchical Structures in Artificial Neural Networks with Their Performance
Authors: Xu Zhuoying , Zhu Yingjun , Hong Binbin , Wu Xinlin , Zhang Jingwen , Zhou Da , Liu Yu 
Published: March 2024

Abstract
This study employs the recently developed Ladderpath approach, within the broader category of Algorithmic Information Theory, which characterizes the hierarchical and nesting relationships among repeating substructures, to explore the structure-function relationship in neural networks. The metric order-rate η, derived from the approach, is a measure of structural orderliness: when η is in the middle range (around 0.5), the structure exhibits the richest hierarchical relationships, corresponding to the highest complexity. We hypothesize that the highest structural complexity correlates with optimal functionality. Our experiments support this hypothesis in several ways: networks with η values in the middle range show superior performance, and the training processes tend to naturally adjust η towards this range; additionally, starting neural networks with η values in this middle range appears to boost performance. Intriguingly, these findings align with observations in other distinct systems, including chemical molecules and protein sequences, hinting at a hidden regularity encapsulated by this theoretical framework.
Nudging interventions on stair use: a scoping review
Authors: Tzikas Alexandros , Koulierakis George , Athanasakis Konstantinos , Merakou Kyriakoula 
Published: March 2024

Abstract

Stair use is a physical activity that can be incorporated into the daily lifestyle of a majority of the population, resulting in several health benefits. Nudges are increasingly used in public health interventions to encourage healthy behaviours such as physical activity in a cost-effective manner. This scoping review aimed to investigate the effect and the characteristics of nudges used on interventions to promote stair use. We reviewed the relevant literature published in PubMed, Cochrane Library, Mendeley & Google Scholar, from January 2009 to May 2022. Eligibility criteria included original studies of any type of design, written in English, targeting healthy adults, reporting nudging interventions, using elevator or escalator as comparators and defining a baseline for comparisons. Initially, 118 publications were identified, and after applying exclusion criteria, 27 articles were included in the analysis. Results showed that most of the nudging interventions had significant positive effect on stair use in several settings. The evidence from this review suggests that incorporating nudges into public health interventions can effectively promote physical activity through increased stair usage. Emphasizing prevention measures in public health interventions may contribute to better health outcomes.
EDUCAÇÃO DESCOLONIZADORA PARA GUINÉ-BISSAU DESDE A EXPERIÊNCIA DOS POVOS HISTORICAMENTE COLONIZADOS
Authors: Almeida Galvão Cauê , Djassi Nbemba 
Published: March 2024

Este trabalho aborda o contexto histórico da Guiné-Bissau em conjunto com o desenvolvimento da educação historicamente e as necessidades observadas para uma educação que necessita se consolidar efetivamente como menos colonial no país. Optamos para essa análise utilizar a pesquisa bibliográfica como forma de levantar um debate sobre os referenciais e apresentar as debilidades do sistema educacional guineense, além de, apresentar algumas soluções ao pensamento crítico na educação. Compreendeu-se no desenrolar da discussão, que diversos problemas constituem as debilidades e limitações do sistema de ensino guineense, mas que, entretanto, os problemas não têm origem somente na condição econômica conforme o país é apresentado ao mundo, mas sim, e sobretudo, nas condições coloniais e nos padrões coloniais que fizeram parte do processo histórico de colonização europeia pelo mundo, e que, ainda fazem parte do pensamento educativo guineense e de boa camada de sua classe política permeados pelo colonialismo mental e as colonialidades do poder, saber e ser.
Ultrastructure of the muscular membrane of the mice gallbladder wall under the influence of ursodeoxycholic acid
Authors: Abaturov A.E. , Babуch V.L. , Tverdokhlib I.V. 
Published: March 2024

Background. The aim of the research was to determine the ultrastructure of the cells of the muscle wall of the mice gallbladder under the influence of ursodeoxycholic acid. Materials and methods. The animals were divided into 2 groups: experimental (n = 17) — mice which received ursodeoxycholic acid at a dose of 100.0 mg/kg and control (n = 13) — intact ones (distilled water). Histological and ultrastructural analyses of gallbladder wall samples of mice were performed. Results. Mitotic figures of myocytes in the wall of the gallbladder bottom (1.794 ± 0.103 %) and body (1.607 ± 0.095 %) in the experimental group of mice were significantly more frequent compared to the controls (0.946 ± 0.058 % and 0.873 ± 0.061 %) (p < 0.01). Enhancing nuclear activity of fibroblasts due to chromatin decondensation and an increase in the number of nuclear pores were observed after the action of ursodeoxycholic acid (0.106 ± 0.007 vs. 0.253 ± 0.018) (p < 0.01). A considerable increase in the number of interstitial cells of Cajal in the muscular membrane of the bottom and body of the gallbladder was noted after the injection of ursodeoxycholic acid (4.61 ± 0.37 mm–2 vs. 2.77 ± 0.23 mm–2) (p < 0.01). Conclusions. Our hypothesis was confirmed by the presence of histological signs of leiomyocyte hyperplasia and an increase in the nuclear activity of fibroblasts in the muscle wall of the mice gallbladder as a result of ursodeoxycholic acid use. Excessive activation of hyperplastic processes of leiomyocytes has an unsettled nature after the injection of ursodeoxycholic acid. An increase in apoptosis of smooth myocytes is observed under the influence of ursodeoxycholic acid. Stimulation of gallbladder wall motility with ursodeoxycholic acid might be associated with an increase in the number of interstitial cells of Cajal in the muscular membrane of the bottom and body of the gallbladder.
Penerapan metode struktural analitik sintetik (SAS) dengan media kartu kata untuk meningkatkan keterampilan menulis permulaan Siswa kelas II
Authors: Hetiawati Ruri C. , Muftianti Agni , Rizal Fauzi Muhammad 
Published: March 2024

Keterampilan menulis permulaan menjadi suatu keahlian mendasar yang esensial dalam proses belajar menulis pada tingkat yang lebih lanjut. Hal ini menjadi modal penting bagi siapa pun yang ingin mengoptimalkan perkembangan kemampuannya dalam menulis. Kurangnya semangat dan motivasi baik dari guru maupun siswa sering menjadi hambatan utama dalam proses pembelajaran menulis. Dalam penelitian ini, digunakan metode campuran atau mix method. Penelitian ini dilakukan di kelas II dengan jumlah siswa 18 orang dengan hasil penelitian menunjukkan peningkatan keterampilan menulis permulaan siswa dari hasil pre-tes dan postes, dengan rata-rata 71.59% yang masuk dalam kategori tinggi. Kendala yang dihadapi siswa adalah kurangnya kepercayaan diri dalam mengemukakan pendapat, namun dapat diatasi dengan memberikan tanya jawab sebagai bentuk latihan yang mendorong kemampuan berpikir, ingatan, keberanian, keterampilan menjawab, dan ekspresi pendapat. Guru menghadapi kendala dalam penerapan metode struktural analitik sintetik dengan media kartu kata karena membutuhkan waktu dan kreativitas dalam pembuatannya. Namun, respon guru terhadap metode ini secara keseluruhan positif. Solusinya adalah membuat media pembelajaran kartu kata yang sederhana, cepat, dan dapat diakses melalui referensi online untuk mempermudah penggunaannya dalam pembelajaran menulis permulaan siswa kelas II.
Kata Kunci: Keterampilan menulis permulaan, Struktural Analitik Sintetik, Siswa kelas II.
Pengembangan Podcast Berbasis Budaya Lokal untuk Siswa Kelas IV Sekolah Dasar
Authors: Khairunnisa Rachmania 
Published: March 2024

Penelitian ini dilatarbelakangi oleh kurangnya ketersediaan sumber belajar dan kurangnya pengembangan sumber belajar di Sekolah Dasar. Padahal, sumber belajar sangatlah penting dan dapat digunakan di Sekolah guna menunjang proses pembelajaran. Saat ini sumber belajar yang digunakan adalah sumber belajar yang disediakan oleh pemerintah, sumber belajar tersebut lebih bersifat umumÂ sehingga materi pembelajaran yang bertujuan untuk mengenalkan kebuyaan lokal kurang bervariasi, secara khusus siswa kurang mendapatkan materi kebudayaan lokal Jawa Barat. Di antara materi kebudayaan lokal yang disampaikan adalah mengenai Kampung Adat di Jawa Barat. Hal tersebut tidak didapatkan pada buku yang disediakan oleh pemerintah. Penelitian ini bertujuan untuk memberikan inovasi pada pengembangan sumber belajar Tema 7 â€œIndahnya Keragaman di Negerikuâ€ yang memuat keragaman budaya lokal. Penelitian ini menggunakan pendekatan kualitatif dengan menggunakan model penelitian EDR (Educational Desain Research) yang merupakan bentuk penjabaran dari Analysis & exploration, Design & Contruction, Evaluation & Reflection. Hasil penelitian menunjukkan bahwa Podcast layak digunakan dan dapat dikembangkan sebagai sumber belajar di kelas IV Sekolah Dasar.
La Brecha de género dentro del contexto de la economía colombiana.
Authors: Barrientos Monsalve María de los Ángeles , Velásquez Blanca Liliana , Paba González Virgilio Adolfo 
Published: March 2024

El propósito de este artículo es conocer la brecha dentro del contexto de las finanzas globales en Colombia, es así en el caso de las organizaciones en la globalización económica y el entorno empresarial las características surgen de la naturaleza misma financiera donde convergen las dinámicas asociativas y empresariales como dimensiones constitutivas, en este tipo de organización y este enfoque cada vez más se viene presentando en la actualidad.. Esto considera la concepción dual de las personas y las asociaciones, la cual se nutren de la economía social, y dentro de esta investigación se usan enfoques significativos en cuanto a métodos de revisión destaca el contexto de criterio global dando métodos descriptivos para llegar a conocer las distintas situaciones oportunas de las finanzas teniendo como objetivo siempre el identificar todos los elementos que propicien la brecha crítica dentro del contexto de la finanzas globales en Colombia para así tener como resultado que los comportamientos una clara visibilidad de los comportamientos y la transparencia informativa investigativa.
Modulation of western South Atlantic marine heatwaves by meridional ocean heat transport
Authors: Goes Marlos Pereira , Dong Shenfu , Foltz Gregory R. , Goni Gustavo J. , Volkov Denis L. , Wainer ILana 
Published: March 2024

Marine heatwaves and cold spells are extreme surface temperature events
that have been associated with adverse societal and ecosystem impacts in
several regions around the globe. Predicting these events presents a
challenge because of their generally short-lived nature and dependence
on air-sea interactions, both locally and remotely. Here we analyze
oceanic propagating features that promote the occurrence of marine
heatwaves and cold spells in the western subtropical South Atlantic. The
main interannual feature detected from satellite sea level data since
1993 shows a westward propagating zonal pattern with a periodicity of
3–5 years. The pattern has a significant in-phase correlation with sea
surface temperature (SST) anomalies in the western South Atlantic,
explaining 82% of the daily extreme warm (90th percentile) and cold
(10th percentile) SST anomalies and consequently modulating interannual
variations in the intensity and duration of marine heatwave and cold
spell events. It is found that meridional oceanic advection plays an
important role in the regional heat budget associated with the
westward-propagating mode, modulating the meridional exchange of
tropical (warm) and extratropical (cold) waters in the western
subtropical South Atlantic region and thereby setting a baseline for
temperature extremes on interannual timescales. This propagating mode is
well correlated (r > 0.6) with the strength of the
meridional overturning circulation at 25°S and 30°S with a lag of
approximately 3–9 months. The lagged response provides a potential
source of predictability of extreme events in the western South
Atlantic.
Simulación clínica al servicio formativo. Percepción de los aprendices de técnico en enfermería
Authors: Zuleta Uribe María Elena , Valles Espinosa Herminsul , Díaz Salas Luz Ángela , Varón Rojas Diego Hernán 
Published: March 2024

El objetivo de este artículo es analizar la percepción de un grupo de aprendices de educación técnica en enfermería, en el ejercicio de simulación cardiopulmonar. Esta actividad se realizó en el Centro de Gestión Tecnológica de Servicios finalizando el año 2021. Con el apoyo teórico de Pamela Jeffries, David Ausubel y otros, se orientó la simulación clínica hacia contextos de aprendizaje significativo y experiencial. La metodología cualitativa utilizada, se basó en la triangulación de instrumentos que incluyó una encuesta, entrevistas y observación participante, aplicada a voluntarios con muestreo intencional, interesados en ejecutar actividades de aprendizaje, usando equipos de alta y baja fidelidad.
Existen muchas investigaciones a nivel mundial relacionadas con la percepción de los estudiantes de las prácticas simuladas, pero este trabajo aborda un aspecto diferencial que implica la mejora de la formación profesional integral, con una estrategia didáctica de enfoque experiencial. Dos de los resultados significativos fueron: el uso de tecnología es relevante porque la relación que se establece entre instructores y aprendices, permite compartir el aprendizaje y profundizarlo. En segundo lugar, el uso de estas técnicas didácticas activas, fortalece la formación integral, en diálogo con el plan educativo institucional.
Erosion Prediction and Soil and Water Conservation Scenario Using The SWAT Model
Authors: Candra Dewi Ni Luh Trisna , Sulastri Ni Nyoman , Arya Arthawan I Gusti Ketut , Ngadisih Ngadisih 
Published: March 2024

Increasing population and development has resulted in inappropriate land use within watersheds that increase soil erosion. One of the hydrologic models that can be used to predict erosion and soil and water conservation in a watershed is SWAT. This research was conducted to predict erosion and the guidance of soil and water conservation in the Yeh Empas Watershed. This research was carried out in several stages, including data collection, data analysis and map validation using the ROC (receiver operating characteristic) and AUC (area under curve) methods. Results revealed that Yeh Empas Watershed had a very light EHL (erosion hazard level) category was found in the downstream area with an annual erosion value of 0 – 14.68 t/ha. In the middle area, the EHL was categorized as light with an erosion value of 15.44 – 57.22 t.ha-1.y-1. The upstream area has moderate EHL with a value of 65.20 – 178.64 t.ha-1.y-1. The validation of the EHL map using the ROC method showed a result of 0.83. This value was classified as very good. It can be concluded that SWAT predictions can be used in estimating erosion and soil and water conservation scenario to reduce 85% erosion. Keywords: Erosion prediction, Soil and water conservation scenario, SWAT models, Yeh Empas Watershed.
Sufism in the Eyes of Muslim Elites in South Sumatra, Indonesia: A Comparison Between Muhammadiyah and Nahdlatul Ulama
Authors: Ariadi Purmansyah , Rulitawati Rulitawati , Nawi Muhammad Zainuddin , Asvio Nova 
Published: March 2024

This study aims at examining the variety of understanding and implementation of sufistic values among elite members of Islamic mainstream organizations, namely Muhammadiyah and Nahdlatul Ulama, in South Sumatra. It uses a field research method and a descriptive-qualitative analysis. This research finds that elite members of two mainstream Islamic organizations in South Sumatra similarly consider the importance of sufistic values, such as faqr, sabr, tawakkal, ikhlas, and ihsan, for perfecting the self. However, they have differed in how these values are implemented. If the former comfortably practices the substantive forms of sufistic teachings, the latter tends to observe sufistic teachings via the route of tarekat (sufi orders). Such difference has led to the variety of Islamic practices and dakwah programs organized by both organizations.
Demak Sufism: Moderation of the Java Islamization in XVI Century In the Study of The Manuscript of Suluk Syeh Bari
Authors: Riyadi Muhammad Irfan , Muzakki Mohammad Harir , Hasanah Nurul 
Published: March 2024

Islamization of the archipelago, especially in Java, took place peacefully in Demak period of the XV - XVI centuries. The retribution of walisanga with its sufism teachings was able to embrace Javanese mysticism in the embrace of Islam. The realization of this attitude of peace (penetration pacifique) without conflict shows that sufism has played an attitude of moderation such as appreciation, tolerance, and inclusive attitude so as to attract the sympathy of Hindu-Javanese mystics into Islam. This paper is intended to reveal how Islamic moderation occurs in Demak, for it is studied by an authentic Sufi manuscript published by Demak written by Sunan Bonang under the title Suluk Syeh Bari. This manuscript is studied using the content analysis method by prioritizing the concept of moderation. This study concludes that Suluk Syeh Bari by Sunan Bonang is the foundation for the teachings of moderate Islamic Sufism since the beginning of Islamization in Java. His moderation teachings include 1) inclusive attitudes in the spirit of divinity, 2) perfection of the soul, realizing noble, wise, and open minded. 3) Open attitude and tolerance towards others through the teachings of Sufism, Ridlo, and always happy. 4) Respect religious acculturation. This attitude will be inherited by his two students, namely Sunan Kalijaga and Syeh Siti Jenar, who gave birth to acculturative Islam (Islam of the archipelago).