bluuebunny/crossref_metadata_2025_split huggingface dataset:
Clinical course of infant colic during treatment with mono- and multiprobiotics
Authors: Novikova V. P. , Magаmedova D. M. , Blinov A. E. , Varlamova O. N. 
Published: February 2024

Introduction. Probiotics have been shown to be effective in the treatment of infant colic for Lactobacillus reuteri. In recent years, multi-strain probiotics have been used for the same purpose.Aim. To evaluate the clinical course of infant colic during treatment with mono- and multiprobiotics and in follow-up.Мaterial and methods. 110 children aged from 1 to 5 months (average age 3.2 ± 0.3 months) suffering from colic were examined. Patients were randomized into three groups: group 1 (n = 30), received the BioGaia Probiotic drops for baby, group 2 (n = 40) – Bac- Set Bab multiprobiotic, group 3 (n = 40) – symptomatic therapy.Results. The average duration of crying of children who received multiprobiotic (group 2) was significantly less than that of children of the first and third groups (group 1 – 1.62 ± 0.5 hours; group 2 – 1.1 ± 0.3 hours; group 3 – 2.5 ± 0.6 hours; p < 0.001). The duration of crying during colic was in correlation with the level of zonulin in the stool (r = 0.58, p < 0.05).Treatment with the multiprobiotic was accompanied by a decrease in the frequency of bowel movements from 4.15 times a day to 3.27 times and was not accompanied by an increase in constipation, while monostrain probiotic and symptomatic therapy did not change the frequency of daily bowel movements and did not affect pre-existing constipation.Conclusions. The multiprobiotic turned out to be more effective than the single-strain monostrain probiotic and symptomatic therapy in the speed of relieving infant colic; it completely stops them in 87.5% of children and reduces them in 12.5%. The effect of multiprobiotic is persistent, relapse was noted in only 13.3% of children, whereas after taking monostrain probiotic the relapse rate was 33.33%. The effect of multiprobiotic is associated with its ability to normalize intestinal microbiota and reduce the permeability of the intestinal wall.
Analysis of upper and lower nappe profiles of large orifice for the design of bottom and roof profiles of high head orifice spillway
Authors: Bhatti Shafqat Hussain , Ur Rehman Habib , Sarwar Muhammad Kaleem , Zaffar Muhammad Waqas , Zafar Muhammad Awais , Tariq Muhammad Atiq Ur Rehman 
Published: February 2024

Abstract

Large orifices are constructed for dams to release water and sediments from reservoirs. Such structures are called submerged spillways. Numerous studies have investigated discharge coefficient, velocity coefficient, and head loss coefficient of large orifices; however, the literature lacks data on the upper and lower nappes of the jets from these orifices. In the present experimental study, the upper and lower nappes are investigated up to 80 m head at different gate openings. The observed minor deviation between the lower nappe profile and trajectory profile equation suggests sensitivity to different factors. The significant role of the coefficient of velocity, averaging at 0.926, highlights its impact on minor deviation. Subsequently, the impact of the solid bottom profile on the discharge coefficient and upper nappe profile are also examined. The results show improvement in discharge coefficient of a sharp-edged large orifice, which increased from 0.69 to 0.74. The results also indicate that the upper nappe profiles and United States Bureau of Reclamation (USBR) profiles are similar. The improvement in the upper nappe profile indicates the significant role of the solid bottom profile, which consequently was found to be helpful in defining the roof profile of an orifice spillway. .
Disease Course and Pulmonary Involvement of COVID-19 during the Delta
Variant Period in Germany: A Comparative Study of Vaccinated and
Unvaccinated Patients at a Tertiary Hospital
Authors: Steuwe Andrea , Ljimani Alexandra , Andree Marcel , Wienemann Tobias , Lübke Nadine , Walker Andreas , Ole Jensen Björn-Erik , The Racoon Study Group  , Radke Karl Ludger , Antoch Gerald , Valentin Birte 
Published: February 2024

Background:
Despite the availability of vaccines, there is an increasing number of SARS-CoV-2-breakthrough-infections.

Objective:
The aim of this study was to determine whether there is a radiological difference in lung parenchymal involvement between infected vaccinated
and unvaccinated patients. Additionally, we aimed to investigate whether vaccination has an impact on the course of illness and the need for
intensive care.

Methods:
This study includes all patients undergoing chest computed tomography (CT) or x-ray imaging in case of a proven SARS-CoV-2 infection between
September and November 2021. Anonymized CT and x-ray images were reviewed retrospectively and in consensus by two radiologists, applying
an internal severity score scheme for CT and x-ray as well as CARE and BRIXIA scores for x-ray. Radiological findings were compared to
vaccination status, comorbidities, inpatient course of the patient’s illness and the subjective onset of symptoms.

Results:
In total, 38 patients with acute SARS-CoV-2 infection underwent a CT scan, and 168 patients underwent an x-ray examination during the study
period. Of these, 32% were vaccinated in the CT group, and 45% in the x-ray group. For the latter, vaccinated patients exhibited significantly more
comorbidities (cardiovascular (p=0.002), haemato-oncological diseases (p=0.016), immunosuppression (p=0.004)), and a higher age (p<0.001).
Vaccinated groups showed significantly lower extent of lung involvement (severity scores in CT cohort and x-ray cohort both p≤0.020; ARDS
42% in unvaccinated CT cohort vs. 8% in vaccinated CT cohort). Furthermore, vaccinated patients in the CT cohort had significantly less need for
intensive care treatment (p=0.040).

Conclusion:
Our data suggest that vaccination, in the case of breakthrough infection, favours a milder course of illness concerning lung parenchymal
involvement and the need for intensive care, despite negative predictors, such as immunosuppression or other pre-existing conditions.
Electrochemical Sensing of Vitamin C Using Graphene/Poly-Thionine
Composite Film Modified Electrode
Authors: Murugan Ridhu Varshini , Magesh Vasanth , Vijayalakshmi K. , Atchudan Raji , Arya Sandeep , Sundramoorthy Ashok K. 
Published: February 2024

Background:
Gastric irritation and kidney problems occur due to excess ascorbic acid
content, whereas the lack of ascorbic acid in the human body leads to poor wound healing, muscle
degeneration, and anemia.

Objectives:
Herein, we report the development of an electrochemical sensor for the detection of
ascorbic acid using poly-thionine/ graphene (P-Th/Gr) modified glassy carbon electrode (GCE) in
0.1 M phosphate buffer solution (PBS) (pH 7.4). Electrostatically fused graphene affixed with
poly-thionine was successfully illustrated for effective voltammetric sensing of ascorbic acid.

Methodology:
FE-SEM indicated the blended edge of a 2D graphene sheet with a deposited thin
layer of polymer, which confirmed the formation of a poly-thionine/graphene composite. The cyclic
voltammetry (CV) technique was utilized for the electrochemical assay of ascorbic acid (AsA,
Vitamin C).

Results:
With the increased concentrations of AsA, the oxidation peak current of ascorbic acid increased
at 0.0 V, and the overpotential showed a decrease compared to bare GCE. The effect of
scan rate on cyclic voltammograms was recorded with 500 μM of ascorbic acid from 10 mV/s to
250 mV/s, which indicated that AsA oxidation is a diffusion-controlled process on poly-thionine/
graphene-modified electrode.

Conclusion:
It was concluded that a poly-thionine/graphene composite-based sensor could be useful
for the determination of ascorbic acid in various biological samples.
Efektivitas Problem Based Learning dan Problem Solving terhadap kemampuan berpikir kritis dan kemandirian belajar matematika
Authors: Chrisdiyanto Endar , Hamdi Syukrul 
Published: February 2024

Penelitian ini bertujuan untuk mengetahui keefektifan pendekatan problem based learning (PBL) dan problem solving (PS) ditinjau dari kemampuan berpikir kritis dan kemandirian belajar siswa. Penelitian ini merupakan penelitian eksperimen semu dengan desain penelitian Nonequivalent Pretest-Posttest Group Design. Populasi dalam penelitian ini siswa SMP di Gantiwarno dan sampel penelitian kelas VIIIC dan VIIID. Instrumen pengumpulan data menggunakan tes kemampuan berpikir kritis, angket kemandirian belajar siswa, dan lembar observasi keterlaksanaan pembelajaran. Validitas isi dilakukan dengan v aiken diperoleh nilai v hitung pretest sebesar 0,97 dan v hitung posttest sebesar 0,99 lebih besar dari v tabel. Estimasi reliabilitas dengan alpha croncbach diperoleh hasil estimasi nilai reliabitas pretest sebesar 0,861, posttest sebesar 0,832, dan angket sebesar 0,90. Hasil reliabilitas alpha croncbach ini 0,70 maka reliabilitas terpenuhi. Hasil penelitian dan analisis data diperoleh bahwa pendekatan PBL lebih efektif dibandingkan pendekatan PS dalam meningkatkan kemampuan berpikir kritis dan kemandirian belajar siswa SMP.
EKSPEDISI LINTAS LAUT JAWA-SULAWESI OLEH ALRI DIVISI VI PASUKAN SEBERANG TAHUN 1946-1947
Authors: Cahyani Eva Suchi Adi 
Published: February 2024

AbstrakMasa Perang Kemerdekaan tahun 1945-1950 merupakan masa krusial bagi bangsa Indonesia dalam rangka mempertahankan kemerdekaannya. Angkatan Laut Republik Indonesia (ALRI) sebagai representasi kekuatan militer matra laut telah menunjukkan eksistensinya di awal perintisan kemerdekaan dengan mengadakan Ekspedisi Lintas Laut ke luar Pulau Jawa. Menggunakan metode sejarah kritis, penelitian ini melalui beberapa tahapan yakni heuristik, kritik sumber, interpretasi, dan historiografi. Hasil penelitian ini menunjukkan bahwa ALRI Divisi VI Pasukan Seberang mempunyai peran penting dalam menyebarluaskan berita kemerdekaan dan membentuk kekuatan militer di wilayah Sulawesi Selatan. Ekspedisi terbagi dalam 6 kloter keberangkatan. Perjalanan ekspedisi yang biasanya singgah dari satu pulau ke pulau lain dimanfaatkan oleh pasukan ALRI untuk menyebarkan berita kemerdekaan kepada penduduk setempat. Angkatan Laut Republik Indonesia Divisi VI Pasukan Seberang berhasil melakukan konsolidasi dengan kelaskaran di Sulawesi yakni Pasukan Harimau Indonesia hingga terbentuk kekuatan gabungan menjadi ALRI Daerah III/Barru dan Daerah I/Mandar Majene.Kata Kunci: Ekspedisi, Jawa-Sulawesi, ALRI. AbstractThe Indonesian War of Independence in 1945-1950 was a crucial period for Indonesia in order to maintain their independence. The Navy of the Republic of Indonesia or ALRI as it is called as a representation of marine military force demonstrated its pioneering nature in the period of independence by conducting Cross-Sea Expedition out of Java Island. Using the critical history method, this research went through several stages, namely heuristics, source criticism, interpretation, and historiography. The result of this study indicate that ALRI Division VI Troops of Seberang had an important role in spreading the news of independence and forming a military power in South Sulawesi. The Navy of the Republic of Indonesia troops took their time from one island to another announcing news of independence to the local people. The Navy of the Republic of Indonesia Division VI Troops of Seberang successfully joined with the paramilitary troops in Sulawesi namely Pasukan Harimau Indonesia and formed combined forces called ALRI Region III/Barru and Region I/Mandar Majene.Keywords: Expedition, Java-Sulawesi, ALRI.
«Я выслан навечно…»: к 80-летию депортации калмыцкого народа (по материалам архивов Казахстана)
Authors:   Al-Farabi Kazakh National University (71, Al-Farabi Ave., 050040 Almaty, Republic of Kazakhstan), Zhakisheva Saule A. , Baltabayeva Kulgazira N. , Kabuldinov Ziyabek E. , Smagulova Anar M. ,   Valikhanov Institute of History and Ethnology (28, Shevchenko St., 050010 Almaty, Republic of Kazakhstan)
Published: February 2024

Introduction. Ethnic deportations were a form of political repression in the USSR. Official Soviet directives clearly proclaimed mass relocations with exact indications of ethnic identities the would-be deportees should belong to. Goals. The study attempts a historical reconstruction of how Kalmyks from the abolished Kalmyk ASSR survived the exile, reviews their legal status, and outlines a social portrait. Materials and methods. The work employs a variety of research methods, such as the source study, information, mathematic/statistical, factual/historic ones and that of computer content analyses for sufficient insights into earlier classified and thus unclaimed sources. The study is the first to examine personal files declassified since November 2021 by the Government Commission for Complete Rehabilitation of Victims of Political Repressions (est. by the order of President K.-Zh. Tokayev), as well as some related documents from departmental archives of Kazakhstan’s Ministry of Internal Affairs and Committee of National Security transmitted in 2021–2023 to the Archive of the President of Kazakhstan. Files dealing with special settlers are also housed at the Archive of the Committee for Legal Statistics and Special Records (Prosecutor General’s Office of the Republic of Kazakhstan) and its departments in Turkistan, Kyzylorda, Akmola, Karaganda and Zhetysu regions, at the State Archive of Kyzylorda Region (its branch — Archive of Sociopolitical History). Results. The Kalmyk deportees started arriving in the Kazakh SSR since January 1944. Despite the Republic was not designated as a region to host the repressed people, the war decided differently. The ethnic Kalmyks — though a minority in the host society to face hard life conditions — never assimilated culturally and showed sustainable social, professional and psycho-physical adaptation skills to the changed circumstances and environments.
«Японский след» в пейзажной лирике казахского поэта Бахытжана Канапьянова
Authors:   Margulan University  (60, Olzhabay Batyr St., 140003 Pavlodar, Republic of Kazakhstan), Temirgazina Zifa K. , Andryuсhshenko Olga K. , Orynkhanova Gibadat A. ,   Kazakh National Women’s Teacher Training University (114/1, Gogol St., 050000 Almaty, Republic of Kazakhstan)
Published: February 2024

Introduction. The influence of the Russian poetic tradition on works of Bakhytzhan Kanapyanov is a well-known fact. However, his poetry, particularly topographical lyrics, has also been influenced by Japanese culture and literature. Goals. The article attempts an insight into landscape lyrics of the Kazakh poet from how it reflects the Japanese philosophy of landscape, most fully expressed in the genres of haiku and tanka. Results. Using the structural-semiotic method, the work reveals that B. Kanapyanov’s landscape poetry is based on the Japanese principle — ‘the beauty of the moment’ which demonstrates the eternity of nature. Just like the Japanese masters of haiku and tanka, B. Kanapyanov depicts nature in small, insignificant details through human sensations and perceptions. Often these sensations complement each\ other: smells and sights, hearings and visions, etc. Traditional Japanese landscape symbolism, e.g. the moon, gets transformed in the poet’s artistic picture of the world depending on his ideological precepts. The Japanese poetic technique also influenced the formal side of B. Kanapyanov’s poetry: preference for syllabic versification, loose adherence to meter and rhyme. Such a significant influence of Japanese culture and literature is explained by the common philosophical attitude to nature among the Kazakh and the Japanese, namely: principles of unity of man and nature, harmonious coexistence of man and nature, and non-interference of man in nature. The syllabic type of versification is also characteristic of not only Japanese but also of the Kazakh language.
Potential of Collagen/PLA-based Nanofibrous Scaffold to Support PC12 Cells and Neural Repair
Authors: Aseer Muhammad , Taleb Mohammad , Arabpour Zohreh , Bhatti Qaisar Abbas , Ghanbari Hossein 
Published: February 2024

Objective: This study attempts to modify Polylactic Acid (PLA) with the natural polymer Collagen (Coll), to develop materials such as an electrospun scaffold that have better mechanical stability and biocompatibility. Retinoic acid (RA), a bioactive material that promotes nerve growth, is to be added to the nanofiber scaffolds as part of this project.
Methods: One of the most important methods we employed in this work to create nanofibrous scaffolds was electrospinning.
Results: The synthesized nanofiber scaffold exhibited a diameter of 255±40 nm and a tensile strength of 175±10.4 N, providing sufficient support for native peripheral nerve repair. The inclusion of Coll enhanced the scaffold's hydrophilic behavior (contact angle: 56±4°), ensuring stability in aqueous solutions. In addition, cell adhesion and proliferation are demonstrated to be improved by PLA composite nanofibers based on Collagen, while PC12 cell adhesion and proliferation are further improved by RA.
Conclusion: Based on their biodegradability, robust mechanical properties, and porous structure, these scaffolds are excellent choices for nerve tissue engineering, according to our findings. The significant increase in PC12 cells' adhesion and proliferation upon the addition of RA demonstrates the cells' potential for nerve repair.
Wolff-Parkinson-White Syndrome in Pregnancy, Labour, and Birth: A Case Study
Authors: Redfearn Sarah , Harrigan Brittany , Redfern Emma 
Published: February 2024

Wolff-Parkinson-White syndrome is a cardiac condition which can complicate pregnancy, especially for patients with a new diagnosis. While common management recommendations for labour have been documented, there is very little information about the condition specifically in the case of a new diagnosis, and even less is documented when a patient declines the recommended monitoring during labour. This is a case study of a primip with a prenatal diagnosis of Wolff-Parkinson-White syndrome. She had one episode about two years prior to pregnancy; a second minor episode occurred near the time that she found out she was pregnant, which pregnancy spontaneously resolved and was not investigated; then at 22+5 weeks’ gestation, she had a significant episode which spurred testing and diagnosis. Symptoms and common management, including the medical care team’s recommendations for pregnancy and labour for individuals with Wolff-Parkinson-White, are discussed. Midwifery care and supporting patient/client-centred informed choice for expectant management versus prophylactic options are explored, including specifically supporting a client choosing care outside of recommendations.
RÉSUMÉLe syndrome de Wolff, Parkinson et White est un trouble cardiaque qui risque de compliquer la grossesse, en particulier pour les patientes et les patients dont le diagnostic est nouveau. Des recommandations de prise en charge courante ont été documentées pour le travail, mais il y a sur cette maladie très peu de renseignements qui traitent spécifiquement d’un nouveau diagnostic et encore moins de la marche à suivre lorsque la patiente ou le patient refuse le monitorage conseillé durant le travail. Le présent article est une étude de cas d’une primipare avec un diagnostic prénatal de syndrome de Wolff, Parkinson et White. Elle aconnu un épisode environ deux ans avant sa grossesse. Un deuxième épisode, mineur, est survenu à peu près au moment où elle a appris qu’elle était enceinte. La grossesse a spontanément résolu le problème, qui n’a pas été examiné. Puis, à 22 semaines et 5 jours de gestation, la patiente a connu un épisode important qui a entraîné la réalisation de tests et l’établissement d’un diagnostic. Les autrices traitent des symptômes et de la prise en charge courante, y compris des recommandations de l’équipe de soins médicaux relatives àla grossesse et au travail des personnes atteintes du syndrome de Woff, Parkinson et White. Elles examinent aussi les soins sage-femme et le soutien du choix éclairé de la patiente ou de la cliente entre la prise en charge non interventionniste et les options prophylactiques, en particulier l’appui d’une cliente choisissant des soins autres que ceux qui sont recommandés.
Efektivitas Bimbingan Perkawinan Pranikah Terhadap Terciptanya Keharmonisan Rumah Tangga
Authors: Andrika Riyansyah.L M , Najwan Johni , Alissa Evalina 
Published: February 2024

This study aims to find out and analyze how the implementation of premarital marriage guidance at the Office of Religious Affairs, Kota Baru District and what are the obstacles that occur in the implementation of premarital marriage guidance at the Office of Religious Affairs, Kota Baru District. The method used in this study is an empirical juridical research method, namely a legal research method that looks at the law in the true sense and how the law is in the community. In this study, the effectiveness of legal norms in this case is the Director General's Decree Number 379 of 2018 concerning Guidelines for the Implementation of Premarital Marriage Guidance for Bride and Groom Candidates. The result of this research is that premarital marriage guidance in Kota Baru District has been implemented. The marriage counseling was held at the Ministry of Religion and the Office of Religious Affairs in Kota Baru District. In the implementation of premarital marriage guidance, there are still many obstacles. Constraints experienced such as the lack of facilitators or resource persons who provide material, the lack of facilities and facilities due to the lack of budget in the implementation of the premarital marriage guidance. So that in the implementation of this guidance, there are differences in the guidance of premarital marriage that is conveyed to the prospective husband and wife.
Abstrak
Penelitian ini bertujuan untuk mengetahui dan menganalisis bagaimanakah pelaksanaan bimbingan perkawinan pranikah di Kantor Urusan Agama Kecamatan Kota Baru dan apa yang menjadi kendala yang terjadi dalam pelaksanaan bimbingan perkawinan pranikah di Kantor Urusan Agama Kecamatan Kota Baru. Metode yang digunakan dalam penelitian ini adalah metode penelitian yuridis empiris yaitu metode penelitian hukum yang melihat hukum dalam artian sebenar-benarnya serta bagaimana hukum dilingkungan masyarakat. Dalam penelitian ini melihat efektivitas norma hukum dalam hal ini adalah Keputusan Direktur Jenderal Nomor 379 Tahun 2018 Tentang Petunjuk Pelaksanaan Bimbingan Perkawinan Pranikah Bagi Calon Pengantin. Hasil dari penelitian iniÂ bahwa bimbingan perkawinan pranikah di Kecamatan Kota Baru telah terlaksana. Bimbingan perkawinan tersebut diselenggarakan di Kementerian Agama dan Kantor Urusan Agama Kecamatan Kota Baru. Dalam penyelenggaraan bimbingan perkawinan pranikah tersebut masih banyak terjadi kendala-kendala. Kendala yang dialami seperti masih minimnya fasilitator atau narasumber yang memberikan materi, masih kurangnya sarana dan fasilitas yang disebabkan minimnya anggaran dalam penyelenggaraan bimbingan perkawinan pranikah tersebut. Sehingga dalam pelaksanaan bimbingan tersebut terdapat perbedaan bimbingan perkawinan pranikah yang disampaikan kepada pasangan calon suami istri.
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