bluuebunny/crossref_metadata_2025_split huggingface dataset:
Understanding Gender Equality Initiatives and Supply Chain Resilience in Sustainability Practices
Authors: Cooper Mason 
Published: April 2024

Abstract
This qualitative research investigates the intersectionality of gender equality initiatives and supply chain resilience within sustainability practices. Through in-depth interviews and thematic analysis, the study explores the integration of gender considerations into supply chain management, challenges and opportunities in promoting gender equality, and the impact of gender equality initiatives on supply chain resilience. The findings reveal the importance of fostering gender diversity, inclusivity, and empowerment within supply chains to enhance adaptive capacity, innovation, and overall performance. Despite significant challenges, collaborative partnerships, leadership commitment, and systemic change offer avenues for advancing gender equality and resilience. Moving forward, efforts to integrate gender considerations into supply chain resilience strategies must be accompanied by robust data collection, monitoring, and evaluation mechanisms to assess progress and track performance. Standardized indicators and benchmarks are essential for demonstrating the business case for investing in gender equality within supply chains and driving meaningful change. Overall, this research contributes to a deeper understanding of the complex dynamics between gender, resilience, and sustainability, offering valuable implications for theory, practice, and policy development in the fields of sustainability management, supply chain resilience, and gender studies.
Diabetic Foot: A MicroRNA-Centric Approach
Authors: de Oliveira Luís Matos , de Oliveira Gabriela Correia Matos , David Tulio Matos , Rocha Roseanne Montargil , Andrade Luís Jesuíno de Oliveira 
Published: April 2024

Abstract
Introdução: Diabetic neuropathy-associated vasculopathy is a significant risk factor for the development of diabetic foot ulcers (DFUs). In the context of DFUs, miRNAs can influence the cascade of molecular events that culminate in healing.
Objective: To design in silico the molecular structures of microRNAs (miRNAs) overexpressed in diabetic foot ulcer healing.
Methods: We conducted a search for the nucleotide sequences of eight miRNAs overexpressed in DFUs, and the following miRNAs were selected: miRNA-146a, miRNA-155, miRNA-132, miRNA-191, miRNA-21, miRNA-203a, miRNA-203b, and miRNA-210. These miRNAs were selected for evaluation in this study based on pre-clinical evidence, differential expression in DFUs, and therapeutic potential. Subsequently, the molecular structures of the eight miRNAs were designed in silico. The nucleotide sequences were retrieved from GenBank, the genetic sequence database of the National Center for Biotechnology Information. The obtained sequences were aligned using multiple alignment algorithms from the RNA Fold web server. RNAComposer, an automated miRNA structure modeling server, was employed for the in silico modeling of the structures.
Results: We performed a search for the nucleotide sequences and designed the molecular structures of the following miRNAs overexpressed in diabetic foot ulcer healing: miRNA-146a, miRNA-155, miRNA-132, miRNA-191, miRNA-21, miRNA-203a, miRNA-203b, and miRNA-210. We generated a tutorial on the molecular models of these eight miRNAs overexpressed in the diabetic foot, based on in silico projections of their molecular structures.
Conclusion: This study demonstrates the in silico design of secondary structures for a selection of eight miRNAs overexpressed in diabetic foot ulcer healing, utilizing techniques from computational biology.
INFORMATION SOVEREIGNTY AND INFORMATION SECURITY IN UKRAINE: CHALLENGES AND REALITIES OF WAR
Authors: Kutsepal Svitlana V. 
Published: April 2024

The article is devoted to the study of the phenomena of information sovereignty and information security of Ukraine under the conditions of Russian military aggression. The thesis is argued that information security occupies a key place in the state national security system; it becomes especially important in the conditions of full-scale military aggression, when the need to protect the subjects of information relations from the negative informational influence of the enemy is actualized. It has been proven that the national interests of Ukraine in the conditions of a full-scale war, which was unleashed by the aggressor country, require the protection of information sovereignty and the creation of favorable conditions for ensuring the country's information security, countering special information operations aimed at undermining
the state sovereignty and territorial integrity of Ukraine. The relationship between the phenomena of information security and information sovereignty was analyzed, and it was established that in the conditions of a full-scale war, the role of state authorities in the context of protecting state and national interests and minimizing the destructive consequences of information aggression significantly increases. It is substantiated that an important condition for the victory of Ukraine is to ensure its information security and information sovereignty. Information security is an important component of the state's national security; therefore, attention to information security issues, provision of effective mechanisms and models for its protection is one of the priority tasks of the state. This requires improving the coordination of the activities of the authorities in relation to the prevention, detection and neutralization of information operations of the enemy, assessment and forecasting of threats to information security, prompt provision of liquidation of their consequences.
Effects of Fe3O4 magnetic nanoparticles on nitrate removal efficiency: an optimization study using response surface methodology
Authors: Demir Özlem , Frat Betül 
Published: April 2024

ABSTRACT

The nitrate contamination of water resources is a serious environmental problem, which may be solved by nitrate sorption onto magnetic nanoparticles. In this study, the effects of Fe3O4 magnetic nanoparticles on nitrate removal were investigated. Fe3O4 was synthesized by a co-precipitation method and used as an adsorbent for nitrate removal. pH, adsorbent dosage, and contact time were considered as the main variables. The effective ranges of these variables were chosen as pH = 4–10, adsorbent dose = 0.5–1.5 g/L, and contact time = 30–90 min. The optimization study was conducted using the Box–Behnken statistical design method. According to the analysis of variance table, it can be concluded that the model is ‘significant’ and the value of R2 was 0.99. The results of the study show that the maximum nitrate removal efficiency was about 91.02%. This was obtained at pH 7, using a dose of 1.3 g/Lof Fe3O4, and a contact time of 28 min.
Preparation of a New Endodontics Sealer and Comparison of its Sealing Ability with Commercial AH Plus Sealer
Authors: Shahi Shahriar , Moslemi Ehsan , Yaltaghiyani Majid , Haghighi Danial , Dizaj Solmaz Maleki , Sharifi Simin 
Published: April 2024

Aim
This study aims to produce and evaluate the sealing ability of a novel endodontic sealer with conventional AH Plus sealer.

Material and Methods
Some materials in powder form were mixed in different percentages by spatulating method in 5 separate groups (A, B, C, D, E). The study of sealing ability was performed on 60 human extracted teeth. The mass of the Bovine Serum Albumin (BSA) was found in the space adjacent to the filler using the adsorption and calibration curve coefficient.

Results
Group C showed the best sealing properties compared with other groups, and its sealing effect was similar to AH Plus as a commercial sealer (p<0.05).

Conclusion
The suitable sealing ability of group C can be due to the simultaneous presence of two polycaprolactones (P767 and P787) in its composition.
A Novel Design for Full-coverage Crown to Assist for Future Endodontic Treatment: A Survey on Difficulties of Access Cavity through Crowns and Pilot In-vitro Study Testing the New Design
Authors: Mashyakhy Mohammed , Adawi Hafiz Ahmed , Abu-Melha Abdulaziz , Binalrimal Sultan , Robaian Ali , Alharbi Sumayah Abdullah , Masmali Lujain Mahdi , Somili Alanood Mansour , Jabari Amal Mohammed , Arishi Mohamed 
Published: April 2024

Aim
Many challenges are faced during opening cavity access through crowns. This study aimed to present a novel design for a full-coverage crown to overcome the difficulties of opening endodontic access and to facilitate root canal treatment.

Methodology
This study comprised two parts: (I) the survey, a cross-sectional questionnaire-based survey was conducted among dentists to assess the degree and type of challenges, complications and difficulties of opening the endodontic access cavity through zirconia and porcelain-fused-to-metal (PFM) crowns, and (II) the experiment, a novel crown design that include a mark occlusally as a guide to access precisely into the pulp chamber was fabricated by taking cone-beam computed tomography scans along with digital impressions of teeth prepared to receive zirconia crowns. The scans were merged with the digital impressions to detect the exact location of the pulp chamber and to make a guide on the crown over the pulp. Subsequently, the crowns were cut using a computer-aided design/computer-aided milling machine. Twenty-one samples in three equal groups (control 1, natural teeth; control 2, full zirconia crowns; and the experimental group, the novel design) were accessed by one operator. The following criteria were evaluated: time spent, quality, and size of the access cavity. The data were collected and analyzed using the SPSS software program at a significance level of P-value < 0.05.

Results
In total, 440 dentists from 28 countries participated in this survey. Generally, the participants reported moderate and difficult degrees of opening through crowns. The most reported challenges and complications were the time spent in the opening and the fracture or chipping of the crown material. For the experiment, no significant difference was found among the groups in relation to the time spent for opening (P = 0.57), with the least required time of access for the experimental group. In addition, no significant difference was found in the quality and size of the access cavity (P = 0.775) among the groups.

Conclusion
Endodontic cavity access through zirconia and PFM crowns is difficult and time-consuming. The novel proposed design utilizing digital dental technology can overcome these issues by preserving the crown, decreasing chair time, and providing less complicated treatment.
CLEC4A Expression as a Prognostic Biomarker and Immunoregulator in Lung Adenocarcinoma: Insights from Immune Cell Infiltration
Authors: Ma Huiyun , Wu Gujie , Chen Hongyu , Hu Qin , Zhang Zhouwei , Wang Fei , Xue Qun 
Published: April 2024

Background
CLEC4A (C-type lectin domain family 4 member A), a member of the C-type (Ca2+-dependent) lectin (CLEC) receptor, is an immunosuppressant of dendritic cells (DCs) and plays an important role in innate and adaptive immunity, however, its role in lung adenocarcinoma (LUAD) and the potential for immunotherapy remains to be investigated.

Methods
To achieve our objectives, we conducted a comprehensive analysis of CLEC4A expression and its correlation with clinical factors in LUAD. We utilized publicly available datasets, such as The Cancer Genome Atlas (TCGA) and other relevant resources, to gather gene expression and clinical data from LUAD patients. Furthermore, we investigated the association of CLEC4A expression levels with clinical pathological staging and prognosis of lung adenocarcinoma. The TIMER database was utilized to analyze immune cell infiltration, while the TISIDB database provided insights into lymphocyte infiltration and immune regulatory factors.

Results
Our analysis revealed a significant correlation between poor prognosis and low CLEC4A expression in LUAD patients. Reduced expression of CLEC4A was associated with adverse clinical factors, indicating its potential as a prognostic biomarker in LUAD. Moreover, we observed a noteworthy relationship between CLEC4A expression and immune cell infiltration. Increased CLEC4A expression was correlated with higher infiltration levels of CD8+ T cells, CD4+ T cells, dendritic cells (DC), and B cells within the tumor microenvironment. This indicates an immunoregulatory role for CLEC4A in modulating immune responses against LUAD. Additionally, our analysis highlighted a positive correlation between CLEC4A expression and the presence of lymphocytes, further emphasizing its potential importance in tumor immunity. Furthermore, the investigation of immune-related factors indicated a potential involvement of CLEC4A in immune regulation within the tumor microenvironment.

Conclusion
This study provides valuable insights into the expression, prognosis, and potential immunotherapeutic role of CLEC4A in lung adenocarcinoma (LUAD). The identified correlations between CLEC4A expression and clinical characteristics, immune cell infiltration, and lymphocyte infiltration highlight the significance of CLEC4A as a potential biomarker and therapeutic target for LUAD. Further research is warranted to elucidate the underlying mechanisms and capitalize on the therapeutic potential of targeting CLEC4A in LUAD. These efforts could contribute to improving patient outcomes and prognosis in LUAD.
The Relationship between Attachment Styles, Maladaptive Caregiving Strategies, and Public Prosocial Tendencies toward the LGBTQIA+ Community: A Cross-sectional Study among Slovak Adults
Authors: Lenghart Daniel , Čerešník Michal 
Published: April 2024

Background
Attachment and caregiving are two mutually interrelated systems. Attachment is reflected in the behaviour and attitude towards the self and others. Caregiving behaviour focuses on relieving distress and promoting the well-being of others. The question is how these two systems contribute to prosocial tendencies towards minority groups. The primary aim of this research was to explore the relationship and the predictive potential of attachment styles and maladaptive caregiving strategies (hyperactivation and deactivation) in relation to public prosocial tendencies towards sexual and gender minorities in a population of Slovak adults.

Objective
This study aimed to analyze the relationship between attachment styles, maladaptive caregiving strategies, and selected public prosocial tendencies toward the LGBTQIA+ community in the Slovak population.

Methods
The participants were 1,000 Slovak adults with a mean age of 26.58 years (SD = 7.035), taking part in the study via an online questionnaire battery. Respondents completed a questionnaire mapping their attachment style (Lenghart and Čerešník, 2022a), which is used to determine the attachment style (secure, avoidant, anxious, and disorganized). The second method was a scale of the caregiving system (Lenghart and Čerešník, 2022b), based on the original version of The Caregiving System Scale (Shaver et al., 2010). The scale maps two basic types of maladaptive caregiving strategies, hyperactivation and deactivation.

Results
The results have demonstrated secure attachment style to be positively correlated with all prosocial tendencies, and negatively correlated with insecure attachment styles and maladaptive caregiving strategies. Insecure attachment styles positively correlated with maladaptive strategies, and negatively correlated with only some prosocial tendencies. Regression analyses showed that the secure attachment style predicted all of the observed prosocial tendencies, the avoidant attachment style negatively predicted two of the six tendencies, the anxious attachment style positively predicted two of the six tendencies, and the disorganised attachment style did not predict any of the prosocial tendencies. The maladaptive hyperactivation strategy positively predicted four of the six tendencies, and the maladaptive deactivation strategy, in contrast, negatively predicted all six prosocial tendencies.

Conclusion
Based on the results of the study, it can be stated that attachment, or attachment style and maladaptive caregiving strategies have a strong and significant impact on public prosocial tendencies towards the LGBTQIA+ community in the Slovak population.
Multi-lamellar Polychromatic Keratopigmentation: A Novel Approach for Corneal Tattooing
Authors: Kiroshka Katerina , Keiserman Igor 
Published: April 2024

Background
Corneal keratopigmentation, commonly known as corneal tattooing, is a cosmetic procedure designed to enhance the visual appearance of non-functional eyes due to congenital, traumatic, or other ocular conditions.

Case Presentation
This case study presents the outcomes of polychromatic lamellar keratopigmentation, a novel technique employed in three patients. The study assesses cosmetic improvements, patient satisfaction, pigment stability, and procedural complications.

Results
The study evaluated the outcomes of polychromatic lamellar keratopigmentation in three patients. The procedure achieved an average cosmetic improvement rating of 4.2 on a scale of 1 to 5, reflecting substantial enhancement in corneal appearance. Patients reported a mean satisfaction rating of 9.2 on a scale of 1 to 10, indicating high contentment. Pigment stability over 1 to 3.5 years was excellent, with no complications reported. This underscores the procedure's effectiveness, durability, and safety as a cosmetic enhancement for non-functional eyes.

Conclusion
The novel polychromatic lamellar keratopigmentation technique is highly effective, with quantifiable improvements in cosmetic appearance, exceptional patient satisfaction, and remarkable pigment stability. This procedure offers a promising and durable option for enhancing the appearance of non-functional eyes.
Pre-exposure Prophylaxis and Post-exposure Prophylaxis Awareness among Men Who Have Sex with Men in Brazil: A National Survey
Authors: Queiroz Artur Acelino Francisco Luz Nunes , de Sousa Alvaro Francisco Lopes , de Oliveira Layze Braz , Batista Odinéa Maria Amorim , Dias Sónia , Mendes Isabel Amélia Costa 
Published: April 2024

Background
Post-Exposure Prophylaxis (PEP) and Pre-Exposure Prophylaxis (PrEP) have been demonstrated to be crucial strategies in preventing HIV transmission. However, there is variability in the adoption of these measures within the population of men who have sex with men (MSM) in Brazil. Considering the Brazilian context of HIV prevention strategies, it is evident that the lack of awareness of these strategies is a primary and significant barrier to their dissemination. Our objective is to examine the factors associated with awareness of PEP and PrEP in a sample of Brazilian MSM.

Methods
We conducted a nationwide cross-sectional study, exclusively online, with a sample of 2,250 MSM. To assess the factors linked to higher or lower awareness, we employed adjusted odds ratios (ORs).

Results
The awareness of PEP and PrEP was reported by 1,228 (54.5%) and 1,044 (46.4%) MSM, respectively. Several factors were associated with awareness of both measures, including income, self-identification as heterosexual or bisexual, knowledge of one's HIV status, and more frequent utilization of healthcare services.

Conclusion
The barriers associated with personal, social, and structural determinants influence the awareness of PEP and PrEP among Brazilian MSM.
Disability-adjusted Life Years of Hepatitis B in Iran during 2009–2019: An Analysis Based on the Global Burden of Disease Study 2019
Authors: Khazaei Zaher , Khanizadeh Sayyad , Soodejani Moslem Taheri , Pordanjani Sajjad Rahimi , Goodarzi Elham 
Published: April 2024

Background and Purpose
Hepatitis B virus infection is currently among the ten leading causes of death from infectious diseases in the world. The aim of the current study is spatial analysis related to life years adjusted by hepatitis B disability in Iran from 2009 to 2019.

Materials and Methods
The study is ecological. Using data from the Global Burden of Diseases (GBD), cause-specific mortality served as the basis for estimating disability-adjusted life years (DALYs). Time trend analysis of DALYs attributed to hepatitis B from 2009 to 2019 and spatial pattern analysis and identification of high-risk and low-risk clusters of DALYs attributed to hepatitis B in Iranian provinces were performed. Time trend changes were evaluated using joinpoint regression analysis.

Results
The most likely high-risk cluster with LLR=238.59 in the West of Iran includes the western provinces of the country (Lorestan, Kermanshah, Hamedan, Markazi, Khuzestan, and Ilam) (relative risk of occurrence 2.31). The three provinces of Lorestan (RR=2.22), Sistan and Baluchistan (RR=1.73), Golestan (RR=1.46) have the highest relative Khazar, and the three provinces of Gilan (RR=0.41), Mazandaran (CIR=0.48) and Kurdistan (CIR=0.51) had the lowest relative risk. During the years 2009 to 2019, the total DALYs decreased by 1.5% annually (p<0.05).

Conclusion
According to the results of the disease control and prevention programs, it can be effective in reducing the disease burden in the country by giving priority to the provinces that are among the high-risk disease clusters.
Investigation of Social Factors Affecting the Health of Hospitalized Children in Pediatric Hospitals
Authors: Mehrasa Somayeh , Abbasi Zahra , Sayedi Seyed Javad , Mask Mahin Kiyani , Raesi Rasoul 
Published: April 2024

Aims
This study was conducted to determine the social factors affecting the health of hospitalized pediatric patients.

Background
Social factors are one of the most influential components affecting community health. Among them, children, as one of the vulnerable groups in society, are heavily influenced by these social factors.

Methods
This cross-sectional study was conducted in 2022 on 357 hospitalized children in Akbar and Dr. Sheikh Mashhad hospitals using random sampling. The data were collected through face-to-face interviews with the parents of the children using the Questionnaire for Social Determinants of Children's Health. Data were analyzed using SPSS-25 statistical software and descriptive and inferential statistical tests at a significance level of 0.05.

Results
The mean age of the children was 5.40±4.72 years, and the mean age of the mothers was 33.32±19.56 years. The mean score of social health of the participants in the study was 56.19±12.18. A total of 244 children (68.3%) had good social health, 85 children (23.8%) had average social health, and 28 children (7.8%) had poor social health. The results showed that the mother's occupation (p=0.047) and the parental family ratio (p=0.029) had a significant relationship with the level of children's social health, however, no significant relationship was observed in other cases (p>0.05).

Conclusion
Understanding and paying attention to threatening, preventive, and enhancing factors of children's social health and addressing them through social interventions and actions can lead to the promotion of social health and reduction of vulnerability in the face of threatening social factors affecting children's health.