bluuebunny/crossref_metadata_2025_split huggingface dataset:
Results of cerebrospinal fluid analysis, neurologic examination findings, and age at the onset of seizures as predictors for results of magnetic resonance imaging of the brain in dogs examined because of seizures: 115 cases (1992–2000)
Authors: Bush William W. , Barr Christina S. , Darrin Edwin W. , Shofer Frances S. , Vite Charles H. , Steinberg Sheldon A. 
Published: January 2006

AbstractObjective—To determine whether neurologic examination findings, results of CSF analysis, or age at the onset of seizures could be used to predict whether results of magnetic resonance imaging (MRI) would be normal or abnormal in dogs with seizures.Design—Retrospective study.Animals—115 dogs.Procedure—Information on results of neurologic examination, results of CSF analysis, age at the onset of seizures, and results of MRI was obtained from the medical records.Results—Results of MRI were abnormal in 61 dogs and normal in 54. Sensitivity and specificity of neurologic examination alone were 77 (47/61) and 91% (49/54), respectively. Sensitivity and specificity of CSF analysis alone were 79 (48/61) and 69% (37/54), respectively. Results of MRI were abnormal for 12 of 28 (43%) dogs with abnormal CSF analysis results and normal neurologic examination results but for only 2 of 35 (6%) dogs with normal CSF analysis and normal neurologic examination results. Similarly, results of MRI were abnormal for 36 of 37 (97%) dogs with abnormal CSF analysis and abnormal neurologic examination results but for only 11 of 15 (73%) dogs with normal CSF analysis results and abnormal neurologic examination results. Age at the onset of seizures (< 6 vs ≥ 6 years old) was not significantly associated with results of MRI.Conclusions and Clinical Relevance—Results suggest that neurologic examination findings and results of CSF analysis are useful in predicting whether results of MRI will be abnormal in dogs examined because of seizures, but age at the onset of seizures is not. (J Am Vet Med Assoc2002;220:781–784)
Use of a pool-raft system for recovery of horses from general anesthesia: 393 horses (1984–2000)
Authors: Sullivan Eileen K. , Klein Lin V. , Richardson Dean W. , Ross Michael W. , Orsini James A. , Nunamaker David M. 
Published: January 2006

Abstract

Objective—To describe the pool-raft recovery system protocol and to evaluate the clinical outcome inhorses that underwent recovery from general anes-thesia using this system.

Design—Retrospective study.

Animals—393 horses that underwent recovery fromgeneral anesthesia in the pool-raft system.

Procedure—Anesthetic records were examined fromhorses recovered from anesthesia in the pool-raft sys-tem between January 1984 and December 2000.Complete medical records of horses were examinedwhen available. Information regarding the anestheticand recovery period was recorded. Horses first recov-ered from general anesthesia in the pool-raft and,once awake, were transported to a recovery stall andlowered to the floor in a standing position.

Results—351 horses underwent 1 pool-raft recovery,and 42 horses underwent multiple pool-raft recover-ies. Most horses were recovered from general anes-thesia within the pool-raft system to safeguard repairof a major orthopedic injury. During 471 pool-raftrecoveries, 34 (7%) horses had complications withinthe recovery pool and 62 (13%) had complicationswithin the recovery stall. Deaths resulted from complete failure of internal fixation, pulmonary dysfunc-tion, or a combination of pulmonary dysfunction andfixation failure in 2% (10/471) of horses that under-went pool-raft recoveries.

Conclusions and Clinical Relevance—The pool-raftsystem is a good option for recovery from generalanesthesia. Although not a fail-safe system, itappears to decrease the complications of recoveringhorses in a high-risk category. Potential disadvan-tages of this system are added expense and man-power necessary in building, maintenance, andusage, as well as size limitations of the raft itself. (J Am Vet Med Assoc 2002;221:1014–1018)
Disposition and clinical use of bromide in cats
Authors: Boothe Dawn Merton , George Kelly L. , Couch Pauline 
Published: January 2006

AbstractObjective—To establish a dosing regimen for potassium bromide and evaluate use of bromide to treat spontaneous seizures in cats.Design—Prospective and retrospective studies.Animals—7 healthy adult male cats and records of 17 cats with seizures.Procedure—Seven healthy cats were administered potassium bromide (15 mg/kg [6.8 mg/lb], PO, q 12 h) until steady-state concentrations were reached. Serum samples for pharmacokinetic analysis were obtained weekly until bromide concentrations were not detectable. Clinical data were obtained from records of 17 treated cats.Results—In the prospective study, maximum serum bromide concentration was 1.1 ± 0.2 mg/mL at 8 weeks. Mean disappearance half-life was 1.6 ± 0.2 weeks. Steady state was achieved at a mean of 5.3 ± 1.1 weeks. No adverse effects were detected and bromide was well tolerated. In the retrospective study, administration of bromide (n = 4) or bromide and phenobarbital (3) was associated with eradication of seizures in 7 of 15 cats (serum bromide concentration range, 1.0 to 1.6 mg/mL); however, bromide administration was associated with adverse effects in 8 of 16 cats. Coughing developed in 6 of these cats, leading to euthanasia in 1 cat and discontinuation of bromide administration in 2 cats.Conclusions and Clinical Relevance—Therapeutic concentrations of bromide are attained within 2 weeks in cats that receive 30 mg/kg/d (13.6 mg/lb/d) orally. Although somewhat effective in seizure control, the incidence of adverse effects may not warrant routine use of bromide for control of seizures in cats. (J Am Vet Med Assoc2002;221:1131–1135)
Characteristics of free-roaming cats evaluated in a trap-neuter-return program
Authors: Scott Karen C. , Levy Julie K. , Crawford P. Cynda 
Published: January 2006

AbstractObjective—To determine characteristics of free-roaming cats evaluated in a trap-neuter-return program.Design—Cross-sectional study.Animals—5,323 free-roaming cats.Procedure—Data collected included sex, maturity, pregnancy status, number of fetuses per pregnancy, cryptorchidism, and occurrence of complications or euthanasia.Results—Adult cats represented 85% of the population, and 57% were female. Overall, 19% of adult females were pregnant, and mean litter size was 3.6 fetuses. Pregnancy rate peaked at 36 to 47% of all females evaluated in March and April and decreased to ≤ 4% from October through January. Cryptorchidism was observed in 1.9% of the males; 0.4% of the adult females had pyometra. Only 1.9% of the cats were already neutered. Euthanasia and unexpected death rates were 0.4 and 0.3%, respectively. The most common severe problems encountered included pyometra, neoplasia, surgical complications, diaphragmatic hernia, debilitation, and chronic inflammatory diseases.Conclusions and Clinical Relevance—Neutering programs for free-roaming cats should include preparations to perform more spays than castrations. Typically, almost half of the female cats trapped during spring will be pregnant. Cryptorchidism is uncommon but is encountered on a consistent basis, so care should be taken to differentiate previous castration from retained testicles. Euthanasia of debilitated cats for humane reasons is rarely necessary, and unexpected deaths occur at a low rate. It is feasible and safe to neuter large numbers of free-roaming cats in large-scale clinics. (J Am Vet Med Assoc2002;221:1136–1138)
Comparison of paste and suspension formulations of omeprazole in the healing of gastric ulcers in racehorses in active training
Authors: Nieto Jorge E. , Spier Sharon , Pipers Frank S. , Stanley Scott , Aleman Monica R. , Smith Donald C. , Snyder Jack R. 
Published: January 2006

AbstractObjective—To compare effects of a commercially available omeprazole paste and a compounded omeprazole suspension on healing of gastric ulcers in Thoroughbred racehorses in active training.Design—Randomized controlled trial.Animals—32 horses with gastric ulcers.Procedure—Horses were assigned to 2 groups on the basis of endoscopic gastric ulcer severity. Group-1 horses were treated with omeprazole suspension for 30 days and with omeprazole paste for an additional 30 days. Group-2 horses were treated with omeprazole paste for 30 days and omeprazole suspension for an additional 30 days. Serum omeprazole concentrations were measured in 4 additional healthy horses after administration of a single dose of each formulation. In all instances, omeprazole was administered at a dose of 4 mg/kg (1.8 mg/lb), PO.Results—Ulcer severity scores on day 0 were not significantly different between groups. On day 30, ulcer severity score was significantly decreased, compared with day-0 score, in group-2 but not in group-1 horses. On day 60, ulcer severity score was significantly decreased, compared with day-0 and day-30 scores, in group-1 horses. In group-2 horses, ulcer severity score on day 60 was significantly lower than the day-0 score but was not significantly different from the day-30 score. Maximum observed serum omeprazole concentration and area under the concentration-time curve were significantly higher after administration of the paste versus the suspension formulation.Conclusions and Clinical Relevance—Results suggest that although administration of the commercially available paste omeprazole formulation was effective in promoting healing of gastric ulcers in these horses, administration of the compounded omeprazole suspension was ineffective. (J Am Vet Med Assoc2002;221:1139–1143)
Neospora caninum serostatus and milk production of Holstein cattle
Authors: Hobson Jamie C. , Duffield Todd F. , Kelton David , Lissemore Kerry , Hietala Sharon K. , Leslie Ken E. , McEwen Beverly , Cramer Gerard , Peregrine Andrew S. 
Published: January 2006

AbstractObjective—To determine whetherNeospora caninumserostatus was associated with milk production among Holstein cattle in Ontario.Design—Case-control study and cross-sectional observational study.Animals—3,702 Holstein cows in 83 herds (casecontrol study) and 3,162 Holstein cows in 57 herds.Procedure—Herds in the case-control study were grouped on the basis ofN caninumabortion status. Herds in the observational study were considered representative of Ontario dairy herds. TheN caninumserostatus of individual cows was determined with a kinetic ELISA. Milk production was modeled to compare seropositive with seronegative animals while controlling for parity, days since parturition, and herd clustering.Results—In the case-control study, 305-day milk production of seropositive cows was significantly less than milk production of seronegative cows in herds with abortions attributable toN caninuminfection and in herds with abortions attributable to pathogens other thanN caninum, but not in herds without abortion problems. In the observational study, 305-day milk production for seropositive cows was not significantly different from milk production of seronegative cows.Conclusions and Clinical Relevance—Results suggest that the association betweenN caninumserostatus and milk production in Ontario Holstein dairy cattle may depend on abortion status of the herd. In herds with abortion problems, regardless of cause,N caninum-seropositive cattle produced less milk, whereas in herds without abortion problems,N caninum-seropositive cattle produced the same amount of milk as seronegative cattle. (J Am Vet Med Assoc2002;221:1160–1164)
Return-to-sensibility problems after penetrating captive bolt stunning of cattle in commercial beef slaughter plants
Authors: Grandin Temple 
Published: January 2006

AbstractObjective—To evaluate efficacy of penetrating captive bolt stunning of cattle in commercial beef slaughter plants and identify potential causes of a return to sensibility among stunned cattle.Design—Observational study.Sample Population—21 federally inspected commercial beef slaughter plants.Procedure—In each plant, stunning of at least 100 cattle (19 large plants) or a minimum of 1 hour of production (2 small plants) was observed, and cattle were evaluated for signs of returning to sensibility on the bleed rail. Cattle with a limp, flaccid head, a lack of spontaneous blinking, and an absence of a righting reflex were considered insensible.Results—In 17 of the 21 (81%) plants, all cattle were rendered insensible before they were hoisted onto the bleed rail. The remaining 4 plants had cattle that had signs of returning to sensibility; these cattle were restunned prior to skinning or leg removal. Of 1,826 fed steers and heifers, 3 (0.16%) had signs of returning to sensibility, whereas 8 of 692 (1.2%) bulls and cows did. Return-to-sensibility problems were attributed to storage of stunner cartridges in damp locations, poor maintenance of firing pins, inexperience of the stunner operator (ie, shooting cattle too high on the forehead), misfiring of the stunner because of a dirty trigger, and stunning of cattle with thick, heavy skulls.Conclusions and Clinical Relevance—Results suggest that efficiency of captive bolt stunning of cattle in commercial slaughter plants can be safely and objectively assessed. Care should be taken to maintain stunners correctly, particularly when stunning bulls and cows with heavy skulls. (J Am Vet Med Assoc2002;221:1258–1261)
Effects of preoperative administration of ketoprofen on anesthetic requirements and signs of postoperative pain in dogs undergoing elective ovariohysterectomy
Authors: Lemke Kip A. , Runyon Caroline L. , Horney Barbara S. 
Published: January 2006

AbstractObjective—To determine the effects of preoperative administration of ketoprofen on anesthetic requirements and signs of postoperative pain in dogs undergoing elective ovariohysterectomy.Design—Randomized, controlled clinical trial.Animals—22 clinically normal client-owned dogs.Procedure—60 minutes before induction of anesthesia, 11 dogs were given ketoprofen (2 mg/kg [0.9 mg/lb], IM), and the other 11 were given saline (0.9% NaCl) solution. Dogs were premedicated with glycopyrrolate, acepromazine, and butorphanol and anesthetized with thiopental; anesthesia was maintained with isoflurane. Ovariohysterectomy was performed by an experienced surgeon, and butorphanol was given 15 minutes before completion of the procedure. Objective behavioral scores and numerical pain scores at rest and with movement were recorded every 2 hours for 12 hours after surgery and then every 4 hours for an additional 12 hours.Results—Preoperative administration of ketoprofen did not reduce the dose of thiopental required to induce anesthesia or the end-tidal concentration of isoflurane required to maintain anesthesia. Activity levels and median objective behavioral scores were significantly higher 4 and 6 hours after surgery in dogs given ketoprofen than in dogs given saline solution. However, mean numerical pain scores in dogs given ketoprofen were not significantly different from scores for dogs given saline solution at any time.Conclusions and Clinical Relevance—Results suggest that preoperative administration of ketoprofen does not reduce anesthetic requirements in dogs undergoing elective ovariohysterectomy but may reduce signs of pain after surgery. Results also suggest that the objective behavioral score may be a more sensitive measure of acute postoperative pain than traditional numerical pain scores. (J Am Vet Med Assoc2002;221:1268–1275)
Comparison of glucose concentrations in blood samples obtained with a marginal ear vein nick technique versus from a peripheral vein in healthy cats and cats with diabetes mellitus
Authors: Thompson Melanie D. , Taylor Susan M. , Adams Vicki J. , Waldner Cheryl L. , Feldman Edward C. 
Published: January 2006

Abstract

Objective—To compare blood glucose (BG) concentrations
measured with a portable blood glucose
meter in blood samples obtained with a marginal ear
vein (MEV) nick technique, from a peripheral venous
catheter, and by direct venipuncture in healthy cats
and cats with diabetes mellitus.

Design—Prospective study.

Animals—10 healthy cats and 11 cats with diabetes
mellitus.

Procedure—On day 1, blood samples were collected
every hour for 10 hours by the MEV nick technique
and from a peripheral venous catheter. On day 2,
blood samples were collected every hour for 10 hours
by the MEV nick technique and by direct venipuncture
of the medial saphenous vein.

Results—For all cats, mean BG concentration for
samples collected by the MEV nick technique was
not significantly different from mean concentration
for samples obtained from the peripheral venous
catheter. For healthy cats, mean BG concentration for
samples collected by the MEV nick technique was
not significantly different from mean concentration
for samples obtained by direct venipuncture. For cats
with diabetes mellitus, mean BG concentration for
samples collected by the MEV nick technique was
significantly different from mean concentration for
samples obtained by direct venipuncture; however,
for the range of concentrations examined, this difference
was not clinically important.

Conclusions and Clinical Relevance—Results suggest
that for the range of concentrations examined,
the MEV nick technique is a reasonable alternative to
venous blood collection for serial measurement of BG
concentrations in cats. (J Am Vet Med Assoc 2002;
221:389–392)
Ultrasonographic appearance of edema caused by injections in the mammary gland attachments of dairy cows
Authors: O'Brien Robert T. , Waller III Kenneth R. , Matheson Jodi S. 
Published: January 2006

AbstractObjective—To determine the ultrasonographic appearance and detectability of edema induced by SC injection of mild silver protein suspension in the mammary gland attachments of dairy cows.Design—Prospective study.Animals—6 lactating cows.Procedure—In each cow, the number of quarters that received injections was randomly assigned. A mild silver protein susoension was injected SC into cranial and caudal mammary gland attachment sites. The number of injections and volume injected were determined on the basis of the appearance of the mammary gland and the desired subjective visual effect. Seventeen sites were chosen for injection and 7 sites did not receive injections. Ultrasonographic images were obtained 1 day prior and 6 days after injections were started. Cows received injections 1, 3, and 5 days after initial sonography. The sonographer was unaware of which sites received injections.Results—Ultrasonography revealed alternating hypoechoic and hyperechoic bands at injection sites. Certain injections caused the intimal surface of the subcutaneous abdominal vein to develop a corrugated appearance. All injection sites were correctly identified ultrasonographically (100% sensitivity, 100% specificity) with a positive and negative predictive value of 1.0.Conclusions and Clinical Relevance—Results suggest that mild silver protein suspension injected SC to enhance the appearance of the mammary glands of dairy cows can be readily detected by ultrasonography. Detection of injection sites should be made on the basis of the distribution and ultrasonographic appearance of edema. (J Am Vet Med Assoc2002;221:408–410)
Evaluation of sedative and cardiorespiratory effects of romifidine and romifidine-butorphanol in cats
Authors: Selmi André L. , Barbudo-Selmi Glenda R. , Moreira Carla F. , Martins Christine S. , Lins Bruno T. , Mendes Guilherme M. , McManus Concepta 
Published: January 2006

AbstractObjective—To determine sedative and cardiorespiratory effects of romifidine alone and romifidine in combination with butorphanol and effects of preemptive atropine administration in cats sedated with romifidine-butorphanol.Design—Randomized crossover study.Animals—6 healthy adult cats.Procedures—Cats were given saline (0.9% NaCl) solution followed by romifidine alone (100 µg/kg [45.4 µg/lb], IM), saline solution followed by a combination of romifidine (40 µg/kg [18.1 µg/lb], IM) and butorphanol (0.2 mg/kg [0.09 mg/lb], IM), or atropine (0.04 mg/kg [0.02 mg/lb], SC) followed by romifidine (40 µg/kg, IM) and butorphanol (0.2 mg/kg, IM). Treatments were administered in random order, with ≥ 1 week between treatments. Physiologic variables were determined before and after drug administration. Time to recumbency, duration of recumbency, time to recover from sedation, and subjective evaluation of sedation, muscle relaxation, and analgesia were assessed.Results—Bradycardia developed in all cats that received saline solution and romifidine-butorphanol or romifidine alone. Preemptive administration of atropine prevented bradycardia for 50 minutes in cats given romifidine-butorphanol. Oxyhemoglobin saturation was significantly decreased 10 minutes after romifidine-butorphanol administration in atropinetreated cats.Conclusions and Clinical Relevance—Results suggested that administration of romifidine alone or romifidine-butorphanol causes a significant decrease in heart rate and that preemptive administration of atropine in cats sedated with romifidine-butorphanol effectively prevents bradycardia for 50 minutes. (J Am Vet Med Assoc2002;221: 506–510)
Cross-sectional study of serum antibodies against Sarcocystis neurona in cats tested for antibodies against Toxoplasma gondii
Authors: Rossano Mary G. , Murphy Alice J. , Vrable Ruth A. , Vanzo Nicole E. , Lewis Stacy K. , Sheline Katherine D. , Kaneene John B. , Mansfield Linda S. 
Published: January 2006

Abstract

Objective—To determine apparent seroprevalence of
antibodies against Sarcocystis neurona in a population
of domestic cats previously tested for antibodies
against Toxoplasma gondii.

Design—Cross-sectional study.

Sample Population—Serum from 196 domestic cats.

Procedure—Banked serum samples submitted to
the Michigan State University Animal Health
Diagnostic Laboratory for T gondii diagnostic testing
were tested for antibodies against S neurona by use
of an indirect fluorescent antibody (IFA) test and a
western blot test. Submission records were analyzed
to determine descriptive statistics and test for associations
between positive results of a test for S neurona
and other variables in the data set.

Results—10 of 196 (5%) samples yielded positive
results for antibodies against S neurona by use of
western blot analysis, whereas 27 samples yielded
positive results by use of the IFA. No association was
found between S neurona western blot test results
and T gondii test results, age, sex, or the reason for T
gondii testing. The S neurona IFA titer was positively
and significantly associated with positive results of
western blot analysis.

Conclusions and Clinical Relevance—Domestic
cats are not likely to play a substantial role as intermediate
hosts in the natural life cycle of S neurona.
Results indicate that natural infection of domestic
cats may occur, and small animal practitioners should
be aware of this fact when evaluating cats with neurologic
disease. The S neurona IFA test had lower
specificity than western blot analysis. (J Am Vet Med
Assoc 2002;220:511–514)