bluuebunny/crossref_metadata_2025_split huggingface dataset:
Infrared Spectroscopic and Density Functional Theory Studies on the Reactions of Zinc and Cadmium Atoms with Ammonia
Authors: Jiang Ling , Xu Qiang 
Published: October 2006

Abstract
Reactions of zinc and cadmium atoms with ammonia molecules in a solid argon matrix have been studied by infrared spectroscopy. MNH3 (M = Zn and Cd) was found from the reaction of ammonia with excited metal atoms, similar to the reaction of ammonia with Hg atom, but quite different from those with other metal atoms (Sc, Ti, V, etc.). The absorptions peaks of HZnNH2 sharply increased upon broad-band irradiation, whereas there was no detectable HCdNH2 produced under the same experimental conditions. Density functional theory calculations were performed on these molecules and the transition states. The agreement between experimental and calculated vibrational frequencies, relative absorption intensities, and isotopic shifts provides strong support for the identification of the products. Furthermore, energetic analysis for possible reaction paths of these reactions is also given.
Synthesis and Spectroscopic Properties of Novel Silacyclic Compounds Containing a Titanium and Some Chalcogen Atoms
Authors: Takeda Nobuhiro , Tanabe Taro , Tokitoh Norihiro 
Published: October 2006

Abstract
Novel silacyclic compounds containing a titanium and some chalcogen atoms, [Tbt(Mes)Si(μ-Ch)2TiCp2] and [Tbt(Mes)Si(μ-Ch)(μ-Ch2)TiCp2] (Ch = S and Se; Tbt = 2,4,6-tris[bis(trimethylsilyl)methyl]phenyl; Mes = mesityl; Cp = cyclopentadienyl), were synthesized by the reactions of the disilene Tbt(Mes)Si=Si(Mes)Tbt with the corresponding [Cp2TiCh5] (Ch = S and Se). The spectroscopic properties of these compounds are presented together with the results of theoretical calculations.
Evidence for an etiologic relation of the epstein‐barr virus to human malignancies
Authors: Henle Werner , Henle Gertrude 
Published: October 2006

AbstractStudies on virus‐induced animal tumors have provided indirect approaches to a search for viruses causing human malignancies. Epstein‐Barr virus (EBV), the cause of infectious mononucleosis, served to illustrate the usefulness of these approaches in linking EBV with Burkitt's lymphoma and nasopharyngeal carcinoma. Despite its demonstrated intimate association with these tumors the role of EBV in their causation remains uncertain.While a passenger role seems excluded, it cannot be decided whether EBV is the primary or a secondary agent in the etiology of the tumors. If the primary cause, immunologic, genetic, virologic or other environmental factors are undoubtedly needed for EBV to express its obvious onco‐genic potential. The data illustrate the difficulties encountered in proving a viral etiology of human malignancies
Otologic and otoneurologic injuries in divers: Clinical Studies On Nine Commercial and Two Sport Divers
Authors: Caruso V. G. , Winkelmann P. E. , Correia M. J. , Miltenberger G. E. , Love J. T. 
Published: October 2006

AbstractIn the past two decades, we have seen a great increase in the number of injuries from commercial and sport diving. During this time, our knowledge of the physiology and pathophysiology of diving has also increased. As a result, we now can accurately diagnose and successfully treat many of these injuries.Of the commercial and sport divers examined as patients in the Department of Otolaryngology at the University of Texas Medical Branch in Galveston, Tex., between September, 1974, and May, 1975, 11 showed positive otologic and otoneurologic findings which are reported herein. One patient was surgically explored for an oval window fistula. In localizing and classifying these injuries, we have utilized extensive and broad‐based test batteries, which include complete history, otologic and otoneurologic physical examination, audiometry, a central auditory test battery, and a vestibular test battery. These tests are described.The findings in each of the divers are illustrated and analyzed. This article further describes the use of these test batteries, which were employed to localize otoneurologic pathology in this sample of injured divers. Based on these cases, we have expanded and modified Edmonds' classification of the etiology of vertigo related to diving. We feel that the test batteries which we describe, or similar tests, should be part of the otologic and otoneurologic workup of injured divers.Index terms are: 1. central auditory tests; ‐2. oval window rupture; 3. diving injuries; and 4. vestibular test battery
Indications for surgery in meniere's disease
Authors: Pulec Jack L. 
Published: October 2006

AbstractMénière's disease has been shown to have multiple causes, each of which requires a specific treatment. Patients who do not respond to medical treatment often are allowed to suffer prolonged disability from their symptoms or develop permanent hearing loss without the benefit of surgery. The physician's uncertainty regarding which patient will ultimately respond to medical treatment or have spontaneous remission of symptoms can cause a delay in what would otherwise have been definitive surgical treatment which would have allowed the patient to return to a happy and productive life.A careful analysis of 120 patients studied intensively for five years has shown that patients who exhibit specific characteristics and diagnostic findings will ultimately require surgery for control and relief of their symptoms, while others can be expected to recover with medical treatment. Fifty‐six of the 120 patients ultimately required surgery to rid them of their symptoms. These patients were almost exclusively of the group considered to be idiopathic, viral, small internal auditory canal syndrome, or caused by physical or acoustic trauma. Those patients who had other causes for their Meniere's disease rarely required surgical treatment and were well controlled by specific medical therapy.These observations would seem to provide us with information which would allow patients who might reasonably be expected to ultimately require surgery, to have surgery provided in the earlier stages of their disease where conservative measures can more often be expected to give complete relief with preservation of hearing. The indications for surgery in patients with Meniere's disease based on this information will be reviewed. The use of this knowledge has significantly reduced the morbidity associated with Meniere's disease
Repair of nasal septal perforation with a silicone button
Authors: Beekhuis G. Jan , Eisenstein Byron 
Published: October 2006

AbstractA symptomatic nasal septal perforation is an annoyance to both the patient and the treating physician. Patients complain of a whistling sound on respiration, persistent nasal crusting, occasional odor, and recurrent bouts of epistaxis. Most of the described surgical methods to attempt to close them, are not very successful; they may require more than one surgical procedure, entailing the associated hospitalization, morbidity, etc., and, at best, dubious outcome.The technique I have used for the past few years was first proposed to me by Vernon Gray M.D.;1 it offers a simple atraumatic office procedure which, has proven to be successful in eliminating the symptoms resulting from a nasal septal perforation. Naturally, the physician should try to determine the underlying cause of the perforation and when practical, treat it. Most cases, however, are due to previous septal surgery or trauma
Malignant external otitis: Long‐term (months) antimicrobial therapy
Authors: Strauss Melvin , Aber Robert C. , Conner George H. , Baum Sheldon 
Published: October 2006

AbstractSince Chandler's initial report in 1968 on “malignant external otitis” (MEO), this entity has been recognized in its earlier stages with increasing frequency. As a result of this, the availability of new antimicrobial agents, and the judicious use of surgery, there has been an improvement in the results of therapy. There remains, however, a subgroup of patients who continue to experience a significant mortality from this infection.A review and selected discussion of our experience with MEO from 1976 to 1979 is presented. Six patients have been diagnosed and successfully treated for MEO. They presented with problems ranging from severe otalgia to multiple cranial neuropathy. For the most part, therapy consisted of the now standard aminoglycoside and carbenicillin combination. Two of the patients were in the high mortality risk group. One of these patients developed an osteomyelitis which extended across the skull base resulting in bilateral cranial neuropathies. His therapy included surgery as well as long‐term (months) outpatient treatment with tobramycin and carbenicillin with an excellent result. The second patient was treated similarly. The efficacy of this approach is discussed as well as the usefulness of radionuclide bone scanning in assessing the course and therapy of patients with MEO.
Histopathology of sudden hearing loss
Authors: Yood Tae H. , Paparella Mirchael M. , Schacern Paricia A. , Alleva Micharl 
Published: October 2006

AbstractEleven temporal bones from eight patients who had clinical histories of sudden hearing loss (SHL) were studied to assess the possible etiopathogenesis. The origin of SHL in seven ears from five patients was obscure, but appeared to be due to multiple causes. Common histopathologic changes in the cochlea, although complex, included atrophy of the organ of Corti and loss of cochlear neurons. Loss of cochlear neurons was the main finding in ears of viral infection. Labyrinthine fibrosis and formation of new bone were seen in two ears associated with vascular insult and in two ears of autoimmune disease. Different histopathologic findings causing SHL were observed even in cases with the same etiology. A case of SHL showing endolymphatic hydrops as the main histopathologic finding is described.
Vocal dysfunction following cricothyroidotomy: A prospective study
Authors: Hoist Magnus , Hertegård Stellan , Persson Anders 
Published: October 2006

AbstractVoice dysfunction is a known consequence of cricothyroidotomy, but few detailed analyses have been published. This study reports an investigation of voice function in 19 patients who underwent cricothyroidotomy during a 12‐month period (54 were patients operated on, 29 survived the primary disease or injury, and 19 agreed to participate in the investigation). The patients were interviewed regarding signs of dysfunction of the cricothyroid muscles, or a diminished external tensor effect on the vocal folds. Laryngos‐copy with a magnifying‐angled endoscope, stroboscopy, phonetography, determination of mean speaking fundamental frequency, perceptual analysis of the voice, and electromyogram of the cricothyroid muscle were all performed. Four patients had signs of diminished external tensor effect on the vocal folds (mild or moderate voice dysfunction), 5 patients had other voice disorders, and 10 were classified as having normal voice. Elective cricothyroidotomy should be avoided in patients with professional or other activities that place heavy demands on the voice.
Gadolinium‐enhanced magnetic resonance imaging in bell's palsy
Authors: Schwaber Mitchell K. , Larson Theodore C. , Zealear David L. , Creasy Jeff 
Published: October 2006

AbstractInflammation of the facial nerve in Bell's palsy can be demonstrated on gadolinium‐enhanced magnetic resonance imaging. We have studied a series of 17 Bell's palsy patients with gadolinium‐enhanced magnetic resonance imaging, and the purpose of this paper is to report our findings and discuss their significance. Most acute Bell's palsy cases demonstrate facial nerve enhancement, usually in the distal internal auditory canal and labyrinthine/geniculate segments. Other segments demonstrate enhancement less often. Gadolinium enhancement occurs regardless of the severity of the paralysis and can persist after clinical improvement of the paralysis. The findings of this study corroborate other evidence that the segments of the facial nerve most often involved in Bell's palsy are the only segments that are most often enhanced with gadolinium‐enhanced magnetic resonance imaging. The role of gadolinium‐enhanced magnetic resonance imaging in the management of Bell's palsy patients is discussed.
Computer‐aided three‐dimensional reconstruction and measurement for multiple‐electrode cochlear implant
Authors: Takahashi Haruo , Sando Isamu , Takagi Akira 
Published: October 2006

AbstractTo assist surgeons in performing multiple‐electrode cochlear implant operations, the spatial relations between middle and inner ear structures in six normal temporal bones were studied using the computer‐aided 3‐D reconstruction method. When viewed through the external auditory canal, the approach used for electrode insertion, and the relation of the malleus to the helicotrema or the scala vestibuli in the second turn of the cochlea were found to vary considerably. In contrast, when viewed from the same transmeatal approach, both the direction and the distance from the stapes footplate to the scala vestibuli of the second turn of the cochlea and helicotrema were found to be quite stable. We concluded that the stapes footplate was a better landmark than the malleus when approaching the helicotrema and scala vestibuli of the second turn of the cochlea during multiple‐electrode cochlear implant surgery.
A comparison of class II antigenicity of human tracheal allografts stored in cialit and in merthiolate
Authors: Bujá Jesús , Wilmes Eberhard , Kastenbauer Ernst , Hammer Claus 
Published: October 2006

AbstractThis report deals with some of the immunological aspects of the transplantation and preservation of human tracheal grafts. The immunological behavior of the transplanted graft depends largely on the interaction of the preservatives with the tissue proteins. Using monoclonal antibodies and the immunoperoxidase staining technique we have investigated the effect of Merthiolate, Cialit, formaldehyde/ Merthiolate, and formaldehyde/Cialit preservation techniques on monomorphic determinants of class II transplantation antigens in human tracheal allografts. Unpreserved grafts were found to express class II antigens. These antigens were totally destroyed after 7 days in formaldehyde and 42 days in Cialit and Merthiolate. Preservation in Cialit and Merthiolate showed a gradual disintegration of the histological structures. In contrast, buffered formaldehyde did not appear to alter the histological structure of the tracheal graft. Irrespective of the mode of preservation, the cartilaginous tissue appeared to persist virtually unaffected. No essential differences were observed between the immunological staining of tracheal grafts preserved in Cialit and Merthiolate.
A modified method of prothrombin time/International Normalised Ratio determination in capillary blood and monitoring oral anticoagulant therapy
Authors: Berkovsky Aron , Sergeeva Elena V. , Suvorov Alexander V. , Uljavova Irina S. , Kachalova Natali D. , Klimovich Ljudmila G. , Samsonova Natali N. , Kozlov Albert A. 
Published: October 2006

AbstractClin Chem Lab Med 2006;44:1214–7.
Gingival Crevicular Fluid Osteopontin Levels in Periodontal Health and Disease
Authors: Sharma C.G. Dileep , Pradeep A.R. 
Published: October 2006

Background: Osteopontin (OPN), a glycosylated phosphoprotein, is a bone matrix component produced by osteoblasts, osteoclasts, and macrophages as a multifunctional cytokine. OPN anchors osteoclasts to the bone surface, and its absence leads to impaired bone resorption. The aim of the present study was to assess the relation between clinical parameters and concentrations of OPN within gingival crevicular fluid (GCF) from inflamed gingiva and periodontitis sites and, subsequently, after the treatment of periodontitis sites.Methods: A total of 45 subjects were divided into the following three groups based on modified gingival index (MGI) and Ramfjord periodontal disease index (PDI) scores: healthy (group I), gingivitis (group II), and chronic periodontitis (group III). A fourth group consisted of 15 subjects from group III, 6 to 8 weeks after treatment (i.e., scaling and root planing [SRP]). GCF samples collected from each patient were quantified for OPN using the enzymatic immunometric assay. Further, the correlation between OPN levels in situ with clinical parameters was analyzed in all groups and before and after treatment in periodontitis patients.Results: The highest mean OPN concentration in GCF (14.347 μg/ml) was observed in group III, and the lowest mean OPN concentration in GCF (2.522 μg/ml) was observed in group I. Its levels in group III decreased to 8.419 μg/ml after treatment (group IV). Further, GCF OPN levels in all the groups showed a statistically significant positive correlation with clinical attachment loss (P <0.05).Conclusions: OPN levels increase in GCF from healthy to periodontitis states, and periodontal treatment results in the reduction of OPN levels. The data indicate that OPN may play a key role in, and could be considered a biomarker of, periodontal disease progression.
Changes in Periodontal and Rheumatological Conditions After 2 Years in Patients With Juvenile Idiopathic Arthritis
Authors: Miranda Letícia A. , Braga Flavia , Fischer Ricardo G. , Sztajnbok Flávio R. , Figueredo Carlos Marcelo S. , Gustafsson Anders 
Published: October 2006

Background: The aim of this study was to monitor changes in periodontal inflammation in patients with juvenile idiopathic arthritis (JIA) for 2 years. We investigated the influence of rheumatic disease activity and antirheumatic medication on clinical and immunological parameters of periodontal inflammation in these individuals.Methods: Two years after a baseline examination, the periodontal and rheumatological conditions of 18 adolescents with JIA and 14 control subjects were described. The clinical periodontal inflammation was monitored by registration of visual plaque, marginal bleeding, probing depth, and clinical attachment loss (AL). Periodontal inflammation was also assessed by analysis of the cytokines interleukin (IL)‐1β and IL‐18 and the collagenase matrix metalloproteinase (MMP)‐8 by enzyme‐linked immunosorbent assay.Results: The erythrocyte sedimentation rate and clinical rheumatological parameters were significantly improved at the 2‐year follow‐up. The number of sites with plaque decreased, and the number of pockets ≥4 mm increased, whereas bleeding levels and the extension of AL remained unchanged. IL‐1β in gingival crevicular fluid decreased significantly in the JIA group after 2 years. No differences were observed for IL‐1β, MMP‐8, or IL‐18 levels between groups after 2 years.Conclusion: Two years after the baseline examination, no clinical or laboratory differences in periodontal inflammation could be found between JIA patients and control subjects.
Protein glycosylation and renal cancer
Authors: Ferguson Roisean E. , Vasudev Naveen S. , Selby Peter J. , Banks Rosamonde E. 
Published: October 2006

Abstract
Glycosylation is the most complex and common posttranslational modification. The development of cancer is associated with profound alterations in cellular glycosylation. Glycosylated proteins (glycoproteins) coat all eukaryotic cells and play pivotal roles in many aspects of tumor progression, including proliferation, invasion, metastasis, and angiogenesis. Recent technological advances in glycobiology have enabled the identification of glycan structures that are associated with particular disease states, thereby facilitating the exploitation of such changes in glycan‐based diagnostics and therapeutics. This review outlines how glycosylation alters with cancer, how such changes may be targeted for diagnostic and therapeutic means, and describes what is known currently about altered glycosylation in renal cancer.
Grid technologies
Authors: O'Neal Douglas W. 
Published: October 2006

Abstract
Shared computing facilities have been in existence since the early days of computing and the manner of sharing has evolved during that time from time‐shared systems to networked computers sharing a user database to peer‐to‐peer networks and now to global grids of mutually accessible systems. Grid computing provides ubiquitous access to computing resources on a scale that no single organization can provide. With scale comes the more efficient utilization of resources, as organizations donate unused resources with the knowledge that necessary resources will be available when they need capacity past what they can provide. The definition of a computer grid, much less its implementation, is still nebulous, but standards are being put into place to provide the structure necessary to provide transparent access to seemingly unlimited resources.
Congenital amegakaryocytic thrombocytopenia—Report of a new c‐mpl gene missense mutation
Authors: Passos‐Coelho J.L. , Sebastião M. , Gameiro P. , Reichert A. , Vieira L. , Ferreira I. , Miranda N. , Guimarães A. , Leal‐da‐Costa F. , Abecasis M.M. 
Published: October 2006

AbstractA 44‐month old girl with congenital amegakaryocytic thrombocytopenia, already with pancytopenia, underwent an unrelated allogeneic cord blood transplantation with recovery of normal blood cell counts. The patient was a compound heterozygote for two c‐mpl missense mutations inherited from both parents, one of them, a G578A exon 4 mutation leading to a cysteine to tyrosine replacement of codon 193, previously unreported. Am. J. Hematol., 2007. © 2006 Wiley‐Liss, Inc.
No association between ADRA2A polymorphisms and schizophrenia
Authors: Clark D.A. , Mata I. , Kerwin R.W. , Munro J. , Arranz M.J. 
Published: October 2006

AbstractThere is evidence to suggest that the α2A‐adrenergic receptor may be involved in schizophrenia. With attention directed at the upstream regulatory region of the gene which codes for this receptor (ADRA2A), we proposed that single nucleotide polymorphisms (SNPs) within this region influences susceptibility to schizophrenia by altering the expression of this receptor. We opted to test for an influence on susceptibility by association study using 112 schizophrenic/schizoaffective disorder patients and 159 controls. The region of interest was screened for SNPs using a combination of bioinformatic searches and sequencing. A total of nine SNPs were discovered, of which four (−5972‐G/A, −2211‐A/T, −1291‐C/G and −261‐G/A) were genotyped in the entire clinical sample. No associations were evident, suggesting no influence for these SNPs in susceptibility to schizophrenia. © 2006 Wiley‐Liss, Inc.