bluuebunny/crossref_metadata_2025_split huggingface dataset:
In‐room display of day and time patient is anticipated to leave hospital: A “discharge appointment”
Authors: Manning Dennis M. , Tammel Karyl J. , Blegen R. Nicole , Larson Lori A. , Steffens Fay L. , Rosenman David J. , Mundell William C. , Naessens James M. , Resar Roger K. , Huddleston Jeanne M. 
Published: February 2007

AbstractBACKGROUND:We learned from a focus group that many patients find discharge to be one of the least satisfying elements of the hospital experience. Patients cited insufficient communication about the day and time of the impending discharge as a cause of dissatisfaction.OBJECTIVE:In partnership with the Institute for Healthcare Improvement, Improvement Action Network collaborative, we tested the practicality of an in‐room “discharge appointment” (DA) display.SETTING AND PATIENTS:Eight inpatient care units in 2 hospitals at an academic medical center (Mayo Clinic, Rochester, MN).INTERVENTION:DA displayed on a specially designed bedside dry‐erase board.MEASUREMENTS:The primary outcome was the proportion of discharged patients who had been given a DA, including same‐day DAs. Secondary outcomes were (1) the proportion of DAs scheduled before the actual dismissal day and (2) the timeliness of the actual departure compared with the DA.RESULTS:During the 4‐month period, 2046 patients were discharged. Of those, 1256 patients (61%) were given a posted DA, of which 576 (46%) were scheduled at least a day in advance and 752 (60%) departed from the care unit within 30 minutes of the appointed time.CONCLUSIONS:With a program for in‐room display of a DA in various hospital units, more than half the patients had a DA set, and most of the DA patients departed on time. Further investigation is needed to determine the effect of DAs on patient and provider satisfaction. Journal of Hospital Medicine 2007;2:13–16. © 2007 Society of Hospital Medicine.
A breakthrough in women's bargaining power: the impact of microcredit
Authors: Osmani Lutfun N. Khan 
Published: February 2007

AbstractThis paper attempts to test empirically whether access to micro‐credit can help poor rural women to improve their bargaining power within the household. The empirical measures of women's bargaining power, or empowerment, used in this paper are underpinned by a bargaining model of the household. By using survey data on the borrowers of the Grameen Bank of Bangladesh and by adopting a methodology that allows for the possibility of self‐selection, this study shows that targeted micro‐credit can have a significantly positive effect on women's bargaining power within the household. Copyright © 2007 John Wiley & Sons, Ltd.
Comparison of different procedures to map reference evapotranspiration using geographical information systems and regression‐based techniques
Authors: Vicente‐Serrano S. M. , Lanjeri S. , López‐Moreno J. I. 
Published: February 2007

AbstractThis paper compares different procedures for mapping reference evapotranspiration (ETo) by means of regression‐based techniques and geographical information systems (GIS). ETo is calculated following the method of Hargreaves (HG) from a dense database of meteorological stations in the northernmost semi‐arid region of Europe, the Ebro valley. The HG method requires the calculation of estimates of extraterrestrial radiation (Ra). We calculated this parameter using two approaches: (1) the common approach that assumes a planar surface and determines the parameter as a function of latitude and (2) using a digital terrain model (DTM) and GIS modelling. The maps were made on a monthly basis using both approaches. We also compared possible propagations of errors in the map calculations for maps derived from modelled layers of maximum and minimum temperatures with those modelled using previously determined local ETo calculations. We demonstrate that calculations of Ra from a DTM and GIS modelling provide a more realistic spatial distribution of ETo than those derived by only considering latitude. It is also preferable to model in advance the variables involved in the calculation of ETo (temperature and Ra) and to subsequently calculate ETo by means of layer algebra in the GIS rather than directly model the local ETo calculations. The obtained maps are useful for the purposes of agriculture and ecological and water resources management in the study area. Copyright © 2007 Royal Meteorological Society
Evaluation of the urban effect of long‐term relative humidity and the separation of temperature and water vapor effects
Authors: Um Hyang‐Hee , Ha Kyung‐Ja , Lee Sun‐Seon 
Published: February 2007

AbstractMonthly relative humidity values for the period between 1905 and 2003 for Busan and Seoul were used to quantify the impact of urbanization on changes in the humidity in an urban area. In this study, the urban effect on observed relative humidity was separated into water vapor and temperature effects using observations in large urban areas and rural sites. The double‐station Evaluation (DSE) is a method that directly compares an urban (Busan) with rural (Miryang) sites. To estimate the urban effect in Seoul, the intermediate (Incheon) and rural (Suwon) stations were used for multistation evaluation (MSE) method. To quantify the urban effect, we assumed that observations in urban areas were influenced by macro‐scale, local and urban scales. Observations from the rural sites did not include the influence of urban areas. Natural variability in the urban areas was derived by assuming that climatic conditions changed simultaneously in the early period of data collection. The sum of the temperature and water vapor effects might not be responsible for the total urban effect owing to errors.The relative humidity of Seoul has continuously decreased over the long term except for a few short periods, and the urban effect in Seoul increased with the temperature effect in the 1970s. In Busan, the urban effect increased rapidly with the water vapor effect after the early 1980s. However, urban effects in both areas have decreased in the past few years. This might be due to changes in land‐use as urbanization developed. The influence of water vapor has decreased after dramatic increases in the 1970s and 1980s, which may be due to the production of excess water vapor due to lifestyle changes. Copyright © 2007 Royal Meteorological Society
Joint degeneration following closed intraarticular fracture in the mouse knee: A model of posttraumatic arthritis
Authors: Furman Bridgette D. , Strand Jens , Hembree W. Chad , Ward Benjamin D. , Guilak Farshid , Olson Steven A. 
Published: February 2007

AbstractPosttraumatic arthritis is one of the most frequent causes of disability following joint trauma. The objective of this study was to develop a model of a closed articular fracture in the mouse knee joint to quantify the temporal sequence of joint degeneration in a model of posttraumatic arthritis. Closed intraarticular fractures were created in the tibial plateau of adult mice (C57BL/6) using a computer‐controlled materials testing system and a custom‐built indenter tip. Tibial plateau fractures were classified and imaged over time using high‐resolution digital radiography. Animals were sacrificed at 2, 4, 8, and 50 weeks following fracture, and the experimental and contralateral control limbs were harvested for histology and micro‐computed tomography (microCT) analysis. By radiographic analysis, tibial plateau fractures closely resembled clinical fractures. More complex and comminuted fractures correlated to significantly higher fracture energies. Histologic analysis demonstrated progressive joint degeneration as measured by a modified Mankin scale, with fibrillation and loss of proteoglycan in the articular cartilage. Subchondral bone thickening was also observed in experimental joints. The induction of a closed intraarticular fracture of the mouse tibial plateau generated a reproducible and clinically relevant joint injury that progressed to osteoarthritis‐like changes by histologic and microCT evaluations. The ability to induce joint degeneration without an osteotomy or open arthrotomy provides a valuable new model for studying the natural sequelae of posttraumatic arthritis. Notably, the use of a murine model will facilitate the use of genetically modified animals for the investigation of specific genes implicated in the pathology of posttraumatic arthritis. © 2007 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 25:578–592, 2007
Age‐related factors affecting the postyield energy dissipation of human cortical bone
Authors: Nyman Jeffry S. , Roy Anuradha , Tyler Jerrod H. , Acuna Rae L. , Gayle Heather J. , Wang Xiaodu 
Published: February 2007

AbstractThe risk of bone fracture depends in part on tissue quality, not just the size and mass. This study assessed the postyield energy dissipation of cortical bone in tension as a function of age and composition. Specimens were prepared from tibiae of human cadavers in which male and female donors were divided into two age groups: middle aged (51 to 56 years, n = 9) and elderly (72 to 90 years, n = 8). By loading, unloading, and reloading a specimen with rest periods inserted in between, tensile properties at incremental strain levels were assessed. In addition, postyield toughness was estimated and partitioned as plastic strain energy related to permanent deformation, released elastic strain energy related to stiffness loss, and hysteresis energy related to viscous behavior. Porosity, mineral and collagen content, and collagen crosslinks of each specimen were also measured to determine the micro‐ and ultrastructural properties of the tissue. Age affected all the energy terms plus strength but not elastic stiffness. The postyield energy terms were correlated with porosity, pentosidine (a marker of nonenzymatic crosslinks), and collagen content, all of which varied significantly with age. General linear models suggested that pentosidine concentration and collagen content provided the best explanation of the age‐related decrease in the postyield energy dissipation. Among them, pentosidine concentration had the greatest contribution to plastic strain energy and was the best explanatory variable of damage accumulation. © 2007 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 25:646–655, 2007
Flandrian sea‐level changes in the Fenland. II: Tendencies of sea‐level movement, altitudinal changes, and local and regional factors
Authors: Shennan Ian 
Published: February 2007

AbstractStratigraphic, micropalaeontologic and radiocarbon data show that since c. 6500 BP the Fenland has been influenced by 7 periods of positive sea‐level tendencies and by 6 periods of negative sea‐level tendencies. Despite the numerous problems associated with the reconstruction of past altitudes of sea level the periods of positive sea‐level tendencies were clearly characterised by a rise in sea level, the development of transgressive overlaps and a landward movement of the coastline. The periods of negative sea‐level tendencies were characterised by the development of regressive overlaps, a seaward movement of the coastline and a reduced or negative rate of sea‐level rise. The various altitudinal errors do not permit the incontrovertible distinction of periods of falling sea levels. All changes within the Fenland were not synchronous and local factors influenced the exact nature of each sea‐level indicator. Dominant regional and local factors have been identified for different areas and different time periods. The chronological and spatial characteristics of the sequences within the Fenland are best explained by a palaeocoastline without supratidal barriers controlling sedimentation. The data indicate an average crustal subsidence in the Fenland of 0.9m/1000 years since c. 6500 BP and the pattern of positive and negative tendencies of sea‐level movement is also seen in the chronologies for north west England and north east Scotland.
Compositional quality of virgin olive oil from two new Tunisian cultivars obtained through controlled crossings
Authors: Manaï Hédia , Haddada Faouzia Mahjoub , Trigui Ahmed , Daoud Douja , Zarrouk Mokhtar 
Published: February 2007

AbstractThis work was carried out on the study of virgin olive oil from two olive descendants obtained through controlled crossings on Chemlali, the dominant Tunisian olive oil variety. These crossings on Chemlali were undertaken to improve its oil quality. Preliminary work evaluating the oil fatty acid composition of the oil of 40 descendants showed the performance of two cultivars among the studied hybrids. These two new cultivars (Hd 034 and Hd 039) have an improved oil composition compared to that of Chemlali. A further study was therefore required for their complete characterization. The analytical parameters (fatty acid composition, total phenolic compounds, chlorophylls and carotenoids contents, oxidative stability, free acidity, peroxide value and ultraviolet characteristics) showed significant differences between oils from both cultivars. Copyright © 2007 Society of Chemical Industry
Trace LC/MS quantitative analysis of polypeptide biomarkers: Impact of 1‐D and 2‐D chromatography on matrix effects and sensitivity
Authors: Rogatsky Eduard , Tomuta Vlad , Jayatillake Harsha , Cruikshank Greg , Vele Louis , Stein Daniel T. 
Published: February 2007

AbstractWe investigated the impact of one dimension (single reverse phase (RP) column) and two dimension (two different RP columns) chromatographic methods on SIM (MS) and multiple reaction monitoring (MRM; MS/MS) performance from human plasma. We find that MRM analysis is clearly preferable for 1‐D applications; however, implementation of SIM detection in conjunction with 2‐D separation technique resulted in an over 60‐fold increase in analyte peak area and improved S/N compared to MRM for our analyte, human C‐peptide. Implementation of a 2‐D RP‐RP technique with SIM detection is capable of eliminating matrix effects and greatly increases signal response and data quality. For two large peptides in complex biological samples, we found that a 2‐D approach performed better than high quality sample preparation together with 1‐D chromatography and MRM, even on a high‐end mass spectrometer.
Preparation and Characterization of Hybrid Quaternized Chitosan/Acrylic Resin Emulsions and their Films
Authors: Wada Tamaki , Yasuda Masafumi , Yako Hiroshi , Matoba Yasuhiro , Uragami Tadashi 
Published: February 2007

AbstractAn acrylic resin emulsion containing a quaternary ammonium salt (hybrid q‐chitosan/acrylic resin emulsion) was prepared by emulsion polymerization using an acrylic monomer with and without DAAM. DAAM was used to incorporate a functional keto group into the acrylic resin emulsion. Furthermore, a hybrid chitosan/acrylic resin emulsion was prepared for comparison. The elution of q‐chitosan in water from the acrylic resin film with a keto group was less than that from the acrylic resin emulsion without a keto group. In addition, the mechanical properties of the hybrid q‐chitosan/acrylic resin film could be modified by q‐chitosan that was crosslinked between acrylic resin particles. Furthermore, hybrid q‐chitosan/acrylic resin films had adsorption ability for formaldehyde, and the antimicrobial properties of these films were superior to those of the hybrid chitosan/acrylic resin film.magnified image
Severe hypokinesis caused by paraneoplastic anti‐Ma2 encephalitis associated with bilateral intratubular germ‐cell neoplasm of the testes
Authors: Matsumoto Lumine , Yamamoto Tomotaka , Higashihara Mana , Sugimoto Izumi , Kowa Hisatomo , Shibahara Junji , Nakamura Koichiro , Shimizu Jun , Ugawa Yoshikazu , Goto Jun , Dalmau Josep , Tsuji Shoji 
Published: February 2007

AbstractWe report a 40‐year‐old man with severe hypokinesis as paraneoplastic manifestation of a microscopic “carcinoma in situ” of the testis. The young age of the patient, along with progressive neurologic deterioration, detection of anti‐Ma2 antibodies, and ultrasound findings of bilateral microcalcifications, led to bilateral orchiectomy, revealing the tumor in both testes. After orchiectomy, neurological symptoms stabilized, but the patient eventually died of systemic complications caused by his severe neurological deficits. Anti‐Ma2 paraneoplastic encephalitis should be considered in patients with severe hypokinesis, and intensive investigation and aggressive approach to treatment is encouraged to prevent progression of the neurological deficits. © 2006 Movement Disorder Society
Depression symptoms in movement disorders: Comparing Parkinson's disease, dystonia, and essential tremor
Authors: Miller Kimberly M. , Okun Michael S. , Fernandez Hubert F. , Jacobson Charles E. , Rodriguez Ramon L. , Bowers Dawn 
Published: February 2007

AbstractDepression is common in Parkinson's disease (PD) and affects 30 to 50% of all patients. In contrast to the wealth of research on depression in PD, little is known about the occurrence of depression in other movement disorders. The primary objective of the current study was to determine whether the high prevalence of depression symptoms seen in PD is also found in other movement disorders, by directly comparing rates of specific depression symptoms and depression severity across PD, dystonia, and essential tremor (ET). Three hundred and fifty‐four patients with PD, 83 patients with dystonia, and 53 patients with ET completed the Beck Depression Inventory (BDI). We found no significant between‐groups differences for depression severity, frequency, or endorsement of specific depression symptoms. Forty‐eight percent of PD patients, 37.3% of dystonia patients, and 34% of ET patients were found to be at least mildly depressed (BDI score of 10 or higher). The most commonly endorsed symptoms were fatigability, difficulty with work, anhedonia, and sleep disturbance. Clinicians should be aware that depression is a frequent problem in dystonia and ET, in addition to PD, and inquire about depression symptoms in these patients so that they can be appropriately treated © 2007 Movement Disorder Society
Stimulation of subthalamic fibre tracts reduces dyskinesias in STN‐DBS
Authors: Herzog J. , Pinsker M. , Wasner M. , Steigerwald F. , Wailke S. , Deuschl G. , Volkmann J. 
Published: February 2007

AbstractRarely, the postoperative management of patients with subthalamic deep brain stimulation (STN‐DBS) is complicated by pharmacologically intractable dyskinesias. Here we report that in three of these patients additional stimulation of a proximal contact located within the subthalamic white matter may lead to a significant reduction of dyskinesias associated with STN‐DBS. We propose that pallidofugal fiber tracts play a major role in the etiopathology of dyskinesias and their blockade through DBS may explain our observations. © 2007 Movement Disorder Society
Memory activation reveals abnormal EEG in preclinical Huntington's disease
Authors: van der Hiele Karin , Jurgens Caroline K. , Vein Alla A. , Reijntjes Robert H.A.M. , Witjes‐Ané Marie‐Noëlle W. , Roos Raymund A.C. , van Dijk Gert , Middelkoop Huub A.M. 
Published: February 2007

AbstractThe EEG is potentially useful as a marker of early Huntington's disease (HD). In dementia, the EEG during a memory activation challenge showed abnormalities where the resting EEG did not. We investigated whether memory activation also reveals EEG abnormalities in preclinical HD. Sixteen mutation carriers for HD and 13 nonmutation carriers underwent neurological, neuropsychological, MRI and EEG investigations. The EEG was registered during a rest condition, i.e. eyes closed, and a working memory task. In each condition we determined absolute power in the theta (4–8 Hz) and alpha (8–13 Hz) bands and subsequently calculated relative alpha power. The EEG during eyes closed did not differ between groups. The EEG during memory activation showed less relative alpha power in mutation carriers as compared to nonmutation carriers, even though memory performance was similar [F (1,27) = 10.87; P = 0.003]. Absolute powers also showed less alpha power [F (1,27) = 7.02; P = 0.013] but similar theta power. No correlations were found between absolute and relative alpha power on the one hand and neuropsychological scores, motor scores or number of CAG repeats on the other. In conclusion, memory activation reveals functional brain changes in Huntington's disease before clinical signs become overt. © 2007 Movement Disorder Society
Reliability of the Burke‐Fahn‐Marsden scale in a multicenter trial for dystonia
Authors: Krystkowiak Pierre , du Montcel Sophie Tezenas , Vercueil Laurent , Houeto Jean‐Luc , Lagrange Christelle , Cornu Philippe , Blond Serge , Benabid Alim‐Louis , Pollak Pierre , Vidailhet Marie ,   The SPIDY Group (French Pallidal Stimulation Group for Dystonia)
Published: February 2007

AbstractBackgroundThe multicenter SPIDY trial (pallidal stimulation for generalized, idiopathic dystonia) recently reported a marked improvement in dystonia which was assessed by the Burke‐Fahn‐Marsden (BFM) scale. However, the reliability of this tool has rarely been evaluated and its use in a multicenter study has never been assessed prospectively.PurposeTo evaluate the concordance between three unblinded clinical raters and one single‐blinded rater for 10 prospective series of ratings on the BFM scale in 22 dystonic patients of the SPIDY study.MethodsTen assessments on the BFM scale were performed under various stimulation conditions at different time points (before surgery and 1, 3, 6, and 12 months afterwards). Patients were first evaluated by three unblinded clinical raters (one per center). All assessments were videotaped and sent to a blinded rater. Intra‐ and inter‐rater reliability was assessed using intraclass correlation coefficients.ResultsThe intra‐rater reliability at inclusion was better for the blinded rater than for the clinical raters. The inter‐rater reliability (comparing the blinded rater with each clinical rater) was “very good” at inclusion, “fair” at month 1 and was “good” at month 3, month 6, and month 12.ConclusionBlinding (rather than video) is probably the key factor in better intra‐rater reliability and can produce more accurate rating than clinical rating. Consequently, a blind procedure should be performed systematically in multicenter studies. As inter‐rater reliability is good in trained unblinded raters, the BFM scale may also be used in the follow up of dystonic patients in movement disorders centers, in clinical practice. © 2007 Movement Disorder Society
Refinement of the DYT15 locus in myoclonus dystonia
Authors: Han Fabin , Racacho Lemuel , Lang Anthony E. , Bulman Dennis E. , Grimes David A. 
Published: February 2007

AbstractInherited myoclonus dystonia (MD) is an autosomal dominant disorder in which we previously mapped a novel locus to chromosome18p11 (OMIM number: 607488). Since no further informative STS markers were found within the flanking shared regions, we utilized single nucleotide polymorphisms (SNP) for fine‐mapping. All known or predicted genes within this region were directly sequenced. We identified three recombinant SNPs in the distal region but none from the proximal region. Our previous linked region has now been reduced to 3.18 Mb but direct sequencing of all seven known and four predicted genes with EST support did not identify any mutations. © 2007 Movement Disorder Society