bluuebunny/crossref_metadata_2025_split huggingface dataset:
Losing ground: business power, standardized assets and the regulation of land acquisition taxes in Germany and Sweden
Authors: Doose Hanna 
Published: March 2024

Abstract
Previous literature on the nexus between land, finance and business power has not systematically analysed the role of the liquidity of businesses’ assets. Combining process tracing with a comparative design, this study contributes a perspective on the role of standardized assets for business power. It investigates land acquisition tax reforms asking why institutional landowners’ structural and instrumental power was successful in Sweden but not in Germany. In Germany, a reform was passed in 2021 which disadvantages the private market institutional landowners compared to their public counterparts. This study argues that the standardization of landed property as liquid stock enabled publicly listed property companies to unite with other stock market actors, increasing their power resources and allowing them to successfully promote their interests due to the liquidity demands of their assets. This stands in contrast to the poorer reception of the liquidity of private market actors in their land-related transactions.
The Charge of the Light Cy-près
Authors: Sanderson Harry , Goldberg Samuel 
Published: March 2024

Abstract
The cy-près doctrine empowers courts to rescue funds held on a frustrated charitable trust by applying them to a different purpose. In Zedra Fiduciary Services (UK) Ltd v HM Attorney General [2023] EWCA Civ 133, the Court of Appeal upheld a decision applying the funds of a substantial and unusual charitable trust towards relieving the UK’s national debt. In this article, we offer a brief history of the trust before considering the Court of Appeal’s judgment. We argue that the decision is justified, but reveals flaws in legislative reforms, which have sought to create more flexibility in the doctrine.
Exploring the relationship between environment and brain morphology in anurans: a comparative phylogenetic approach
Authors: Rodrigues Maycon Vitor , de Carvalho-e-Silva Sergio Potsch , Rödel Mark-Oliver , de Mello Bezerra Andressa 
Published: March 2024

Abstract
The correlation of ecological and behavioural characteristics with morphological features of brain structures has been recurrently corroborated for different vertebrate taxa, such as mammals, birds, and fishes. Here, we asked whether such correlations can also be detected in amphibians, an animal group of great interest due to its great behavioural and ecological diversity. We analysed the shape of two brain regions, cerebellum and optic tectum, of 67 species from 32 families of the order Anura (frogs and toads), applying 2D geometric morphometrics in a phylogenetic context. We found species that share similar environments and daily patterns have a similarly shaped cerebellum and optic tectum, with diurnal and arboreal species with more varied brain shapes. We did not find a correlation between activity mode or lifestyle with shape for both brain regions; however, we found that shared ancestry had an influence in their evolution. Future studies including a higher number of species from each ecological group, and from more families, would help to better clarify whether the patterns found here are a general rule for anurans.
Long-term Change of Low Anterior Resection Syndrome in Survivors of Rectal Cancer: Longitudinal Follow-up of a Randomized Controlled Trial
Authors: He Siqi , Zhang Jinquan , Wang Runxian , Li Li , Sun Weipeng , Wang Jianping , Deng Yanhong , Liang Weiwen , Dou Ruoxu 
Published: March 2024

BACKGROUND:
Postoperative bowel dysfunction, also known low anterior resection syndrome, is common in rectal cancer survivors and significantly impacts quality of life. Although long-term longitudinal follow-up is lacking, improvement of the syndrome is commonly believed to happen only within the first two years.

OBJECTIVE:
This study aims to depict the longitudinal evolvement of low anterior resection syndrome beyond 3 years and explores factors associated with the change.

DESIGN:
Longitudinal long-term follow-ups were performed for the single center with the largest cohort within the multi-center FOWARC randomized controlled trial.

SETTING:
A quaternary referral center.

PATIENTS:
Individuals diagnosed with rectal cancer who received long-course neoadjuvant chemotherapy or chemoradiotherapy, followed by sphincter-preserving radical proctectomy.

MAIN OUTCOME MEASUREMENTS:
Change of low anterior resection syndrome score and stoma status.

RESULTS:
Of the 220 patients responding to the first follow‐up at a median of 39 months, 178 (80.9%) responded to the second follow-up after a median of 83 months. During the interval, mean low anterior resection syndrome score improved from 29.5 (95% confidence interval [CI] 28.3–30.7) to 18.6 (95% CI 16.6–20.6). 56 (31.5%) patients reported improvement from major to no/minor severity, and 6 (3.4%) patients had new stoma due to severe bowel dysfunction. Neoadjuvant radiation (p = 0.016) was independently and negatively associated with improvement of the score.

LIMITATIONS:
Loss of follow-up during the long-term follow-ups.

CONCLUSION:
Most rectal cancer survivors with low anterior resection syndrome continued to improve beyond 3 years after proctectomy. Neoadjuvant radiation was negatively associated with long-term improvement of low anterior resection syndrome. See Video Abstract.
A Retrospective Study for Labia Minora Reduction by Serrated-shaped Resection
Authors: Wang Shou-Jie , Xu Kai , Chen Xiao-Ling , Shi Bang-Hui , Wang Hui , Wu Li-Hong , Chen Chun-Ye 
Published: March 2024

Background:
The demand for genital plastic surgery has increased dramatically among female patients globally. Although various labia minora reduction procedures have been applied with different indications, advantages, and disadvantages, none has been universally accepted as the best method. So, we presented an innovative strategy for this increasingly demanded reconstructive procedure.

Methods:
In this retrospective study, we included 29 patients seen between November 2020 and May 2023 with hypertrophic labia minora. The patients with hypertrophic labia minora after serrated-shaped resection were included for analysis. Patient satisfaction and complications were evaluated through the follow-up after the operation.

Results:
Patients with a mean age of 27.1 years (range 19–47 y) performed labia minora reduction via serrated-shaped resection. One patient experienced incision dehiscence, requiring additional surgical revision. One patient experienced postoperative cosmetic asymmetry and also performed secondary repair surgery. One patient experienced urinary retention, which was relieved after urinary catheterization. High overall patient satisfaction has been achieved after a median follow-up of 6.7 months (range 1–24 months). No flap necrosis, sexual dysfunction, or hypertrophic scarring has been reported.

Conclusions:
Results suggested that serrated-shaped resection is a novel technique for repairing hypertrophic labia minora with high efficiency and satisfaction. The procedure could effectively improve the appearance of the labia minora and reduce complications.
Intraoperative Anaphylaxis to Gelatin during Alveolar Bone Grafting for Cleft Palate
Authors: Gehring Michael B. , Freedman Jonathan D. , Wolfe Brandon , French Brooke M. , Khechoyan David Y. 
Published: March 2024

Summary:
Intraoperative anaphylaxis can be life threatening. Anaphylaxis to gelatin-based topical hemostatic agents is an underrecognized hypersensitivity. To date, only 21 cases of intraoperative anaphylaxis have been reported for gelatin-based hemostatic agents. In this article, we report the case of a 10-year-old male patient who sustained anaphylaxis after the use of Gelfoam during harvest of a bone graft. Rapid diagnosis and treatment of intraoperative anaphylaxis is imperative to prevent adverse outcomes. Referral to an allergist for identification of the allergen and appropriate notation in the medical record are paramount to avoid future anaphylactic events. Surgeons should avoid gelatin-based hemostatic agents, such as Gelfoam, in patients with reported intolerance of gelatin-based foods and medicines.
Bilateral Hematoma Following Air Travel after Breast Augmentation: A Cautionary Tale and Literature Review
Authors: Kyriazidis Ioannis , Antoniou Antonios , Demiri Efterpi , Pavlidis Leonidas , Papas Athanasios 
Published: March 2024

Summary:
In this study, we report a rare incidence of bilateral hematoma following air travel in a patient who had recently undergone breast augmentation surgery. The case underscores the potential risks associated with flying shortly after such procedures. Through a literature review, we aimed to explore the incidence rates and highlight the need for further research in this area. This case report aims to raise awareness among healthcare professionals and patients about the need for cautious post-surgical travel planning to mitigate the risk of similar complications.
Microsurgical Practice with Use of Smartphone Camera as the Microscopic Field
Authors: Johnson Elise A. , Johnson R. Michael 
Published: March 2024

Summary:
Accessibility of microsurgical equipment is a major barrier to proper training of surgeons before live patient free flap surgery. A technique is presented that uses a smartphone camera as the microscopic field, eliminating the need for an expensive operative microscope for surgical practice. A convenient and cost-effective simulation protocol could reduce the time frame of the microsurgery learning curve. Furthermore, the use of the smartphone video function may allow improved feedback by mentors, improving access and communication between microsurgical teachers and learners. The PocketSuture smartphone stand is a commercially available device that allows the smartphone camera to be used as magnification. The proposed education protocol included suture practice, vessel dissection, and free tissue transfer in nonliving animal models, with vessel anastomosis and patency confirmation performed with a smartphone camera for field magnification. Video of the suturing technique allowed feedback from the mentor. A progressive suturing protocol leading to the ability to perform microsurgical anastomosis on nonliving animal models was developed. The basic costs for the stand, instrument set and suture were less than $500. The PocketSuture smartphone stand can be used for microsurgical training with real-time video for plastic surgery learners with limited access to microscopes and local mentors.
Effects of Marijuana Use in Patients Undergoing Abdominal Free Flap Breast Reconstruction
Authors: Al-Saghir Tala , Vraa Alexander , Sawar Kinan , Jacobsen Gordon , Evangelista Maristella S. , Atisha Dunya 
Published: March 2024

Background:
Marijuana use has been associated with vascular inflammation and clotting, resulting in endothelial damage and arteritis. As marijuana use rises in the United States, few studies have evaluated its impact on surgical outcomes and wound healing in free flap breast reconstruction.

Methods:
A retrospective cohort study of patients undergoing abdominal free flap breast reconstruction between 2016 and 2022 at a large metropolitan healthcare system was performed. Patient demographics, comorbidities, procedural details, and complications were analyzed. Minor complications were defined as skin or fat necrosis not requiring intervention, nipple loss, any wound requiring management in the clinic, hematoma, and seroma. Major complications were defined as reoperation, flap loss, cardiac or thromboembolic events, and hospital readmission. Active marijuana users were those with marijuana use within 12 weeks of surgery.

Results:
In total, 168 patients underwent 276 deep inferior epigastric artery-based flaps for breast reconstruction. There were 21 active marijuana users. There were no significant differences in patient demographics, cancer treatment, or minor and major complications. However, there were higher rates of active nicotine use (P = 0.001) and anxiety/depression amongst active marijuana users (P = 0.002). Active users had higher rates of bilateral breast reconstruction (P = 0.029), but no significant differences in other operative details.

Conclusions:
Active marijuana use of unknown frequency may be safe in patients undergoing breast free flap reconstruction. Advising marijuana abstinence preoperatively may not alter patient outcomes. Further studies of greater sample size are needed to evaluate marijuana’s impact on outcomes associated with breast reconstruction using free flap.
Evaluating the Effectiveness of Lacrimal Gland Botulinum Toxin Using the TEARS Score
Authors: Hunt Samantha Vicki , Schulz Christopher Brian , Malhotra Raman 
Published: March 2024

Purpose:
Botulinum toxin (BoNTA) lacrimal gland injections are one treatment option for managing epiphora. Outcomes for epiphora in existing studies are subjective and lack grading. This study utilized validated grading instruments to evaluate the efficacy of BoNTA lacrimal gland injections.

Methods:
Prospective study evaluating the TEARS score and quality of life in patients receiving incobotulinum toxin (Xeomin) lacrimal gland injections for epiphora. Epiphora was graded using the TEARS score. Quality of life was evaluated using the watery eye quality of life score. Etiology, benefit duration, complications and additional injections were recorded.

Results:
Of the 28 patients, (median age 67.5 years), 19 (68%) had facial palsy gustatory epiphora (GE). Median effect duration was 13 weeks. Improvements in tearing frequency (T), clinical effects (E), and activity limitation (A) were seen in 57%, 57%, and 71% of patients, respectively. Median watery eye quality of life score improved from 42.4/100 ± 10.1 to 10.6 ± 15.5 (p < 0.001). Alongside crocodile tears, reflex tearing R-scores improved in 68% of patients with GE vs. 11% with non-GE causes (p = 0.004618). In total 89% of patients with GE and 56% with non-GE requested repeat injections. Self-reported percentage improvement ranged from 0% to 100% (median 60%, interquartile range 10%–76.25%).

Conclusions:
This is the first study reporting the outcomes of BoNTA lacrimal gland injections using validated TEARS and watery eye quality of life scores. Clinical and quality of life improvements are seen in most patients. Patients with GE achieve an additional improvement in dry eye-related reflex tearing alongside crocodile tears which both improve with BoNTA. TEARS data supports using BoNTA in these patients and is a useful validated grading instrument for epiphora.
Contemporary Perioperative Outcomes of Open Retroperitoneal Lymph Node Dissection for Testicular Cancer
Authors: Qian Zhiyu , D'Andrea Vincent D. , Xiao Boyuan , Kielhofner Jane , Yim Kendrick , Stone Benjamin V. , Alkhatib Khalid Y. , Mossanen Matthew , Preston Mark , Steele Graeme S. , Clinton Timothy N. 
Published: March 2024

Purpose:
Retroperitoneal lymph node dissection (RPLND) is an essential component of multimodal treatment of testicular cancer. The latest data on the perioperative outcomes of RPLNDs performed using the open approach (O-RPLND) dates back over a decade. We report our contemporary institutional perioperative outcomes with O-RPLND.

Materials and Methods:
We retrospectively identified all patients who underwent O-RPLND between 2013 and 2022 across our institution. Clinical and demographic data were reviewed and recorded. Descriptive statistics and univariate analysis were performed with patients stratified according to primary RPLND and post-chemotherapy RPLND (PC-RPLND).

Results:
Our cohort included a total of 144 men. Seventy-seven percent of all cases were PC-RPLND. The PC-RPLND cohort showed higher preoperative clinical stages (81% vs 26% above cN1, P < .001; 41% vs 1% Stage 3, P < .001). PC-RPLND pathologies were more likely to be teratoma and necrosis or fibrosis (43% vs 6% and 39% vs 33%, P < .001). Estimated blood loss was significantly higher in the PC-RPLND group (291 vs 125 cc, P = .004). Operative time was longer for PC-RPLND (242 vs 196 minutes, P = .011). Length of stay and 30-day readmission rate were not significantly different between groups and averaged 4.3 days and 12%, respectively. Our most common complication was ileus (5%), followed by chyle leak (3%).

Conclusions:
While PC-RPLND becomes prominent for treating advanced testicular cancer, our recent data suggest positive perioperative results with O-RPLND. With long-term outcome data needed to appropriately select patients for robotic RPLND, O-RPLND in experienced hands continues to improve its outcome and remains the standard approach in the modern era.
The efficacy and safety of tonifying-kidney and invigorating-blood circulation (Bushen-Huoxue) formula on renal fibrosis in patients with chronic kidney disease: A protocol for systematic review and meta-analysis
Authors: Li Xiaoxiao , Liang Weijie , Lu Haiyun , Wu Jiandi , Luo Xiuwen , Kang Zhi , He Qian , Jiang Chenglong 
Published: March 2024

Background:
The incidence of chronic kidney disease (CKD) is increasing and the progression of renal interstitial fibrosis (RIF) in end-stage renal disease is attributed to the development of various CKD. One of the treatments for RIF is an oral treatment known as Bushen-Huoxue (BSHX), which stimulates blood circulation and tonifies the kidney. Randomized controlled trials of BSHX treatment of RIF have been reported, but their efficacy and safety have not been comprehensively examined. Therefore, our study aims to describe the efficacy and safety of oral application of the traditional Chinese medicine (TCM) formula of BSHX on treating RIF in CKD by systematic analysis and meta-analysis.

Methods:
A total of 13 databases, including PubMed, EMBASE, MEDLINE, Web of Science, Cochrane Library, SpringerLink, WHO International Clinical Trials Registry Platform, Wanfang China database, China National Knowledge Infrastructure, Chinese Biomedical Literature Database, Chinese Scientific Journal Database, and China’s Conference Papers Database and China Dissertation database will be searched from inception to July 2023. In addition, other suitable search strategies will be used as well to complete this review. All randomized controlled trials that use the BSHX formula for RIF to apply TCM treatments externally for CKD will be included. The eligible studies will be selected to enroll by 2 independent researchers following a predetermined protocol. The review manager software (Rev-Man 5.3) will be used to assess the risk of bias, reporting bias, and data synthesis.

Result:
We will compile and discuss the recent examples of the TCM BSHX formula treatment for RIF in CKD.

Conclusion:
We will provide strong evidences for evaluating the efficacy and safety of the TCM BSHX formula treatment for RIF in CKD.
Deferoxamine in the management of COVID-19 adult patients admitted to ICU: a prospective observational cohort study
Authors: Almutary Abdulaziz M. , Althunayyan Saqer , Bagalb Amal S. , Mady Ahmed F. , Alenazi Latifa , Mumtaz Shahzad A. , Al-Hammad Zahrah , Abdulrahman Basheer , Al-Odat Mohammed A. , Mhawish Huda , Aletreby Waleed Th. , Altartouri Maymouna , Memish Ziad A. 
Published: March 2024

Background:
COVID-19 infection is associated with high mortality, and despite extensive studying the scientific society is still working to find a definitive treatment. Some experts postulated a beneficial role of Deferoxamine.

Aim:
The aim of this study was to compare the outcomes of COVID-19 adult patients admitted to the ICU who received deferoxamine to those who received standard of care.

Methods:
Prospective observational cohort study, in the ICU of a tertiary referral hospital in Saudi Arabia to compare all-cause hospital mortality between COVID-19 patients who received deferoxamine and standard of care.

Results:
A total of 205 patients were enrolled, with an average age of 50.1±14.3, 150 patients received standard of care only, and 55 patients received deferoxamine additionally. Hospital mortality was lower in deferoxamine group (25.5 vs. 40.7%, 95% CI=1.3–29.2%; P=0.045). Clinical status score upon discharge was lower in deferoxamine group (3.6±4.3 vs. 6.2±4, 95% CI: 1.4–3.9; P<0.001), as was the difference between discharge score and admission score (indicating clinical improvement). More patients admitted with mechanical ventilation were successfully extubated in the deferoxamine group (61.5 vs. 14.3%, 95% CI: 15–73%; P=0.001), with a higher median ventilator-free days. There were no differences between groups in adverse events. Deferoxamine group was associated with hospital mortality [odds ratio=0.46 (95% CI: 0.22–0.95); P=0.04].

Conclusions:
Deferoxamine may have mortality and clinical improvement benefits in COVID-19 adults admitted to ICU. Further powered and controlled studies are required.
Simulation-based perioperative anaesthesia information management practice: cross-sectional study
Authors: Admassie Belete Muluadam , Ferede Yonas Admasu , Mekonnen Zemenay Ayinie , Sisay Menarguachew Atanaw , Worku Misganaw Degu 
Published: March 2024

Background:
Perioperative anaesthesia record completeness is very essential skill of the anaesthesia profession at the time of operation in the health setting. During perioperative, anaesthesia care sometimes there may be missing important information of the patient, medication taken or planned. This study aimed to improve perioperative anaesthesia information management practice.

Methodology:
Pre-interventional and post-interventional cross-sectional study was conducted from 21 June to 25 July 2022 on 164 anaesthesia record filled by 51 anaesthesia care provider in pre-interventional and post-interventional phase. Data were collected using a semi-structured questionnaire and the data entered by Epi-data software (version 4.6) and analyzed by using SPSS version 26. For all indicators, the projected completion rate was 100%. Indicators with completion rates of greater than 90% were classified as acceptable, while those with completion rates of 50% were seen as urgently needing improvement.

Results:
Pre-interventional result: among all indicators, none of the indicators had 100%, completeness rate. Postoperative nausea and vomiting management orders, the names of the surgeon and anaesthetist, the location of the intravenous cannula, the maintenance of anaesthesia, the total amount of fluid supplied, the content of the consent discussion, and null per ose status, age, and weight of the patient were some of the markers that were identified below average (50%) and in need of significant improvement. Post-interventional result: when compared with the pre-interventional result, their documentation skills were improving after discussions with stakeholders and the relevant bodies; however, none of the indicators attained 100% completion rate.

Conclusion and recommendation:
Even after the interventions, the desired completion rate was not attained. As a result, it requires ongoing instruction on perioperative anaesthesia information management according to the standard perspectives.