bluuebunny/crossref_metadata_2025_split huggingface dataset:
Crystal structure of methyl-1-(p-tolyl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylate, C20H20N2O2
Authors: Gao Yanrong , Dang Xiaolin , Wang Yanjiao , Liu Bin , Tang Wenqiang 
Published: April 2024

Abstract
C20H20N2O2, monoclinic, P21 (no. 4), a = 8.3293(4) Å, b = 11.3947(5) Å, c = 8.9536(4) Å, β = 108.489(2)°, V = 805.92(6) Å3, Z = 2, Rgt
(F) = 0.0495, wRref
(F
2) = 0.1094, T = 150 K.
Skin conductance algesimeter is unreliable during sudden perioperative temperature increases
Authors: Kongsgaard Ulf E. , Menchini Robin Johansen , Larsen Stein Gunnar , Juul-Hansen Knut Erling 
Published: April 2024

Abstract

Objectives
Pain assessment in anesthetized and non-communicative patients remains a challenge. Clinical signs such as tachycardia, hypertension, sweat and tears, have a low specificity for pain and should therefore ideally be replaced by more specific monitoring techniques. Skin conductance variability has been demonstrated to establish a patients’ sensitivity to pain, but may be influenced by temperature changes that leads to profuse sweating. The aim of this pilot study was to test skin conductance changes during sudden temperature changes due to hyperthermic intraperitoneal chemotherapy (HIPEC) perfusation.

Methods
We investigated skin conductance algesimeter (SCA) in ten consecutive patients undergoing cytoreductive surgery and HIPEC. Results from the SCA was compared to other standard physiological variables at seven time points during the surgical procedure, in particular during the period with hyperthermic intraabdominal perfusion leading to an increase in the patients core temperature.

Results
Nine out of ten patients had an increase in the SCA measurements during the HIPEC phase correlating the increase in temperature.

Conclusion
SCA is unreliable to detect increased pain sensation during sudden perioperative temperature changes in adult patients.
INTELLIGENT TIME SERIES DATA ANALYSIS OF CRYPTOCURRENCY MARKET DYNAMICS BASED ON OHLCV DATASET AND MOMENTUM TECHNICAL INDICATORS
Authors:   Odesa Polytechnic National University, Uzun I. S. , Lobachev M. V. ,   Odessa Polytechnic National University
Published: April 2024

Abstract. This article presents an analysis of the historical dynamics of the cryptocurrency market based on time series data using the OHLCV dataset. The study presents the results of calculations of the main cryptocurrency market momentum technical indicators. Using intelligent computational methods, the paper assesses patterns and trends in the data of major cryptocurrencies. The study emphasizes the importance of technical analysis in understanding the volatile landscape of digital currencies.	Key words: time-series, data analysis, cryptocurrency market, momentum indicators, technical analysis indicators, OHLCV.
To attract a moth: Wind tunnel and field testing of plant odor and light stimuli and their combination for Ostrinia nubilalis
Authors: Zhukovskaya Marianna I. , Grushevaya Inna V. , Miltsen Alexander A. , Selitskaya Oksana G. , Shchenikova Anna V. , Frolov Andrei N. , Tóth Miklós 
Published: April 2024

AbstractThe European corn borer, Ostrinia nubilalis (Hubner), relies on multimodal sensory information to find food, mates, mating and ovipositional grounds. Successful phytosanitary monitoring demands for the bait for the field traps to obtain the most reliable representation of pest abundance. Attraction to light and blend of key components of host plant odor, was tested both in the laboratory and field conditions. Ultraviolet light, which was the most effective in the wind tunnel experiments, was further tested in the field alone and in combination with bisexual lure. Bisexual lure, being attractive in the lab, as well as in the field, did not improve responses to ultraviolet in both experimental designs. All three baits attracted significantly more females than males in the field. Wind tunnel experiments revealed that ultraviolet elicited the shortest response latencies either alone or paired with the odor bait. The lack of synergistic effect between attractive light and odor stimuli is an important issue for pest monitoring. The possible reasons for the observed lack of synergy are the hierarchy of behavioral responses to different stimuli or the intensities of both stimuli are critically important for attractivity of combined stimulus and differ from separately presented ones.
Lehetne-e csökkenteni az enyhe koponyasérültek sürgősségi koponya-CT-vizsgálatainak számát?
Authors: Viczei Alexandra , Lapis István , Kiss Gergő , Solti Árpád , Szeifert György 
Published: April 2024

Bevezetés: A koponya- és agysérüléseket (craniocerebralis
traumák) nemzetközileg elfogadott standardok alapján osztályozzuk, gyakoriságuk
és megoszlásuk országonként eltérő. Magyarországon 100 000 lakosra évente
átlagosan 2000 koponyasérülés jut, s ezeknek legfeljebb a negyede jár kórházi
felvétellel. Az elrendelt sürgős CT-vizsgálatok száma az Egyesült Államokban és
hazánkban is a duplájára nőtt az elmúlt 20–30 évben. A készült koponya-CT-k
közel 90%-a bizonyult negatívnak. Az enyhe fejsérülést vagy agyrázkódást
szenvedett betegek rövid ideig tartó eszméletvesztésről, átmeneti fejfájásról,
retrograd amnesiáról vagy dezorientációról számolnak be, a GCS (Glasgow-i Coma
Skála) szerinti 13–15-ös értékű tudatállapot mellett. Fizikális vizsgálat után
ezek a betegek sürgősségi osztályon való megfigyelést követően elbocsáthatók
lehetnek, mivel az eddigi gyakorlat alapján az elvégzett koponya-CT-vizsgálat
kóros eltéréseket nem igazolt. Célkitűzés: A CT nem hatékony
használata jelentősen növeli a betegek felesleges sugárterhelését, valamint az
egészségügyi ellátás költségeit is. Ezek mérséklésére többféle, külföldön már
jól bevált szabályozási rendszer van érvényben, amelyek azonban hazánkban még
nem váltak rutinszerűen alkalmazhatóvá. Saját beteganyagunk adatainak
áttekintésével azt vizsgáltuk, hogy szükséges volt-e minden esetben a
koponya-CT-vizsgálat. Módszer: Megvizsgáltuk a Békés Vármegyei
Központi Kórház Sürgősségi Osztályán jelentkező koponyasérült betegek ellátási
gyakorlatát. Eredmények: Retrospektív elemzésünk alapján a
Kanadai Koponya CT Szabályt alkalmazva a sürgős koponya-CT-vizsgálatok száma kb.
70%-kal lett volna csökkenthető. Következtetés: A külföldön már
alkalmazott standard rendszerek hazai használatával lehetőség nyílna az enyhe
fejsérültek ellátási hatékonyságának javítására a magyarországi sürgősségi
betegellátó osztályokon is. Orv Hetil. 2024; 165(14): 538–544.
Turmeric and Mangosteen Extract Modulate Autophagy Gene Expression in High-Fat Diet-Induced Rats
Authors: Gunadi Julia Windi , Jasaputra Diana Krisanti , Pangestuti Balqist Sriprobo , Wahyudianigsih Roro , Lesmana Ronny 
Published: April 2024

Background: High-fat diet (HFD) increases the risk of obesity, metabolic syndrome, coronary artery disease, and chronic kidney disease, resulting in lipotoxicity. Turmeric and mangosteen are two ingredients mostly used in Indonesian food, and are known for their antihyperlipidemic and antioxidant effects. The aim of this study was to explore the effect of turmeric and mangosteen on autophagy gene expression in HFD-induced kidneys in rats model.Methods: The study was an experimental study, including 25 male Wistar rats aged 8 weeks, divided into 5 groups with a completely randomized design; group with a standard diet as negative control group, the group with a high-fat diet as a positive control group, and the HFD groups with turmeric or mangosteen or fenofibrate. The study was conducted in Maranatha Biomedical Research Laboratory from January to November 2022. Autophagy gene expression (LC3, p62) was measured along with the histopathological scoring to observe necrosis, inflammation, and fat degeneration state. Data was analyzed using One Way ANOVA or Kruskal Wallis and post hoc Least Significant Difference or Mann Whitney.Results: There were significant differences in inflammation in groups treated with mangosteen (p=0.007); in fat degeneration in groups treated with mangosteen and fenofibrate (p=0.007). Furthermore, the LC3 gene expression was increased in all HFD groups as well as the p62 gene expression in group treated with turmeric (p=0.020) and fenofibrate (p=0.005).Conclusions: Mangosteen decreases inflammation and fat degeneration scoring, while turmeric increases autophagy in the kidney of HFD induced Wistar rats.
Validation of the Russian version of Spine Oncology Study Group Outcomes Questionnaire
Authors: Tsyrenova E. B. , Shchelkova O. Yu. , Sofronov D. I. , Borzov K. A. , Valiev A. K. , Kulaga A. V. , Matanova V. L. 
Published: April 2024

Introduction. Surgical intervention is the only or main component of combination treatment of the majority of malignant tumors of the spine. Pronounced pain syndrome and neurological deficit caused by spinal tumors significantly worsen disease progression, decrease patients’ quality of life.Aim. To develop a Russian-language version of a specialized questionnaire to study the quality of life of patients suffering from tumor lesions of the spine Spine Oncology Study Group Outcomes Questionnaire (SOSG-OQ).Materials and methods. In 82 patients with tumors of various parts of the spine who are treated at the N.N. Blokhin National Medical Research Center of Oncology, psychometric evaluation of the SOSG-OQ questionnaire was performed confirming its convergent validity and reliability–consistency (Cronbach’s α = 0.899).Results. Exploratory factor analysis confirmed adequacy of the questionnaire’s structure and its conformity to the basic factor model. Instruments of the validated Russian version of the SOSG-OQ questionnaire (text and data analysis instructions) for its use in clinical practice are presented. Results obtained using the new SOSG-OQ questionnaire show a significant decrease in quality of life of patients with spinal tumors. Additionally, after surgery patients described their health-related quality of life significantly higher than prior to treatment.Conclusion. Validated Russian version of the SOSG-OQ questionnaire can be recommended for application in oncological clinic for more precise and differentiated evaluation of performance status, emotional condition, experience of patients, evaluation of life circumstances associated with the disease to promote more targeted and personalized psychological care.
La ayuda humanitaria como remesas políticas en las trayectorias migratorias de empresarios venezolanos radicados en Bogotá
Authors: Medina Marcela Ceballos , Sepúlveda Santiago Castillo 
Published: April 2024

Resumen
El artículo aborda las trayectorias migratorias de sectores empresariales de Venezuela radicados en Bogotá, con el fin de analizar el lugar que ocupa la acción humanitaria en estas trayectorias, y examinando las estrategias de inmigración en el lugar de destino. En particular, evalúa la ayuda humanitaria como estrategia de reproducción social, y su relación con la noción de transnacionalismo político, identificando su papel en una inserción “por arriba” en Colombia. Se plantea que la acción humanitaria adquiere el carácter de “remesas políticas”, en el marco de una estructura de relaciones que involucra el origen y el destino; así como su función en la difusión de mensajes e influenciadas por la posición social de estos sectores y su posición política. La metodología comprende análisis de 18 entrevistas a profundidad con personas pertenecientes a sectores empresariales que emigraron en el periodo 1990-2019, y el uso de las trayectorias migratorias como herramienta de análisis.
Functional outcome of diaphyseal fractures of forearm in children treated with titanium elastic nailing system
Authors: Hossain Kazi Shahadat , Rafi Abdullah Al , Rabbi Qaisur , Mia M. Shoeb , Kawchar M. Abdur Rouf 
Published: April 2024

Background: Forearm fractures are common injuries in children, with diaphyseal fractures of the forearm being among the most frequent injuries treated in the pediatric population. This study aimed to assess the functional outcome of diaphyseal fractures of the forearm in children treated with the titanium elastic nailing system.
Methods: This prospective observational study was conducted at the Department of Orthopaedics, Mainamoti Medical College, Cumilla, Bangladesh from January 2020 to December 2022. The study included 67 patients aged 6-15 with diaphyseal forearm fractures treated with the titanium elastic nailing system, selected through purposive sampling. MS Office tools were used for data analysis.
Results: According to the functional outcome criteria described by Price et al., it was observed that in the highest number of patients (86.56%), the functional outcome was excellent, followed by good, fair, and poor outcomes found in 8.96%, 2.99%, and 1.49% of the cases, respectively. As the postoperative complications, the delayed union was found among 4%, and skin infection was found among 3% of cases.
Conclusions: Considering the excellent outcomes and lower complication rate, the titanium elastic nailing system may be considered a very effective and safe treatment method for the management of diaphyseal fractures of the forearm in children.
Thoughts on international research partnerships
Authors: Carter Ian 
Published: April 2024

What is new?

This paper explores the approaches an institution might take internally to support the different types and scales of research partnerships. It identifies three levels of partnership (individual, group or topic, and institutional), and suggests the variations in support each requires.

What was the approach?

The paper is based on personal experiences and observations of practice, originally written as a briefing note for a colleague.

What is the academic impact?

While other papers consider the relationship between the partners, this paper focuses on the conditions for success within one organisation, which will ultimately have an effect on the other members of the partnership. It complements those papers that examine the inter-relationships between the partners.

What is the wider impact?

Practitioners will be able to use these reflections to understand, evaluate and if necessary evolve their own institution’s approach to research partnerships. Funders and policy makers might similarly be able to use them in setting their expectations for the partnerships they create or require.
Factors Influencing Postnatal Care Utilization Among Women in Sub-Saharan Africa: A Scoping Review
Authors: Moyo Enos , Moyo Perseverance , Dzinamarira Tafadzwa , Murewanhema Grant , Ross Andrew 
Published: April 2024

BACKGROUND:Considerable progress has been made globally in improving maternal and child health. However, Sub-Saharan Africa (SSA) and South Asia together accounted for 86% of all maternal deaths in the world during the 2000–2017 period. It is estimated that more than 60% of global maternal deaths occur during the postnatal period. The utilization of postnatal care (PNC) services remains low in SSA. This scoping review aimed to determine factors that influence PNC utilization among women in SSA.METHODS:Peer-reviewed articles published in English from 2018 to 2023 were searched from Google Scholar, ScienceDirect, MEDLINE, African Journals Online, SCOPUS, and PubMed databases. Two authors independently screened the articles and extracted the data.RESULTS:Thirty-nine articles were included in this review. Thirty-three of the studies were of a quantitative cross-sectional study design, four were mixed-methods, and two were qualitative studies. The review identified several enablers and barriers to PNC utilization among women, which were categorized into individual, community-level, and healthcare system factors. Some of the individual factors included the place of residence, marital status of the woman, employment status, educational level of both the woman and her partner, and household income. Health system factors included accessibility of healthcare facilities, availability of resources, and the quality of healthcare.CONCLUSION:To improve PNC utilization in SSA, several strategies should be implemented. These strategies should address issues such as women’s empowerment, accessibility of healthcare facilities, the quality of healthcare services, and healthcare services financing.
Identification of Interwell Interference Based on Hydrogeochemical Characteristics of Produced Water from Coalbed Methane Wells: A Case Study in the Southern Qinshui Basin, China
Authors: Tu Mingkai , Wang Xiaoming , Hou Shihui , Chen Wenwen , Dang Zheng 
Published: April 2024

Summary
Interwell interference is the superposition effect of coalbed methane (CBM) reservoir pressure. This study aims to provide a new direction for the quantitative analysis of interwell interference from the hydrogeochemical characteristics of produced water from CBM wells. A total of 24 produced water samples collected from the Panhe (PH) group, Shizhuangnan (SZN)-1 group, and SZN-2 group in Qinshui Basin were selected for the comparative analysis. The water type of all water samples is characterized by Na-HCO3, with Na+ being the main total dissolved solids (TDS) provider. The self-similar major ionic characteristics of the PH and SZN-2 groups are prone to the occurrence of interwell interference. The δD and δ18O show that the main source of produced water is atmospheric circulating water. The similar isotope characteristics of produced water in the PH and SZN-2 groups represent that there is remarkable interwell interference. Sr, As, Cu, Ga, Li, Rb, Sn, Mo, and V are selected as indicator elements. In the cluster analysis, all CBM wells form a single cluster in the PH and SZN-2 groups in the first three iterations, indicating interwell interference. According to the established fuzzy discriminative model, interwell interference is divided into two types—strong interwell interference and weak interwell interference. Most CBM wells in the PH and SZN-2 groups show strong interwell interference. This study can provide theoretical foundations for the dynamic pressure regulation and well pattern infilling of CBM wells.
Imaging of brain electric field networks
Authors: Frank Lawrence , Galinsky Vitaly , Krigolson Olave , Tapert Susan F. , Bickel Stephan , Martinez Antigona 
Published: April 2024

Abstract

We present a method for direct imaging of the electric field networks in the human brain from electroencephalography (EEG) data with much higher temporal and spatial resolution than functional MRI (fMRI), without the concomitant distortions. The method is validated using simultaneous EEG/fMRI data in healthy subjects, intracranial EEG data in epilepsy patients, and in a direct comparison with standard EEG analysis in a well-established attention paradigm. The method is then demonstrated on a very large cohort of subjects performing a standard gambling task designed to activate the brain’s ’reward circuit’. The technique uses the output from standard EEG systems and thus has potential for immediate benefit to a broad range of important basic scientific and clinical questions concerning brain electrical activity, but also provides an inexpensive and portable alternative to function MRI (fMRI).
Waters Biomonitoring of the Marrecas River (Paraná, Brazil) at Different Trophic Levels
Authors: Couto Mário Sérgio Braga do , Salla Larissa , Biffi Mariana Tonello , Alves Geiciane Locatelli , Follador Franciele Aní Caovilla , Soares Izabel Aparecida , Hellmann Liliane , Schmitz Ana Paula de Oliveira , Pokrywiecki Juan Carlos , Pokrywiecki Ticiane Sauer , Manosso Fernando Cesar , Düsman Elisângela , Hendges Elvis Rabuske , Andres Juliano , Gomes Eduardo Michel Vieira , Aruda Gisele 
Published: April 2024

Abstract

One of the biggest environmental problems generated by anthropocentric activities is the pollution of water sources. Monitoring these areas is of great importance for maintaining their quality and for human heath, because the distribution of drinking water depends on the river ecosystem. This study aimed to realize the biomonitoring, at different trophic levels, of the Marrecas River Waters (Paraná, Brazil). The samples were collected in 2020 at nine points, three in the rural area and six in the urban area along the Marrecas River. Physicochemical and microbiological analyses, toxicity test with Artemia salina, escape test with Eisenia fetida, cytotoxicity with mammalian cells and cytotoxicity and mutagenicity test with Allium cepa were realized. The results show that the Marrecas River water quality is compromised, mainly in the urban region, possibly due to the inadequate use and occupation of its basin and inadequate disposal of effluents in the region. In addition, the study shows the importance of testing at different trophic levels, as they have different sensitivity, as is the case of A. cepa, which was the only one to demonstrate high levels of mutagenicity for the source of the Marrecas River.
Effect of Septoria tritici blotch (Zymoseptoria tritici) on yield and yield components of bread wheat (Triticum aestivum L.) in Holeta, Ethiopia
Authors: Yewste Tsigehana , Jemal Abaynew , Tadesse Yitagesu 
Published: April 2024

Abstract

Septoria tritici blotch is one of the most important yield-limiting diseases of wheat in Ethiopia. Yield loss assessment was conducted in a Randomized Complete Block Design with three replications at the Holeta Agricultural Research Center experimental field during the main cropping season of 2022/2023. The experiment was conducted to determine the integration effect of wheat variety, fungicide, and planting date on the grain yield of bread wheat. Evaluation was started from the onset of the disease 63 days after planting. The effects of Septoria tritici blotch on grain yield were significant (P < 0.05) when the two varieties Alidoro and Pavon − 76 planted on July 10th and treated with fungicide at a rate of 0.75 l/ha, produced the highest yields of grain (6.4and 5.7 ton/ha respectively). Results also showed that the highest yield losses (64.1 and 50.0%) were computed on untreated control plots of the cultivars Pavon 76 and Alidoro respectively, which were planted on 10th July and 1st July, compared with maximum protected experimental treatment for both cultivars. Furthermore, data on cost-benefit analysis showed that Alidoro treated with 0.75l/ha fungicide rate had the highest net benefit of 340330 B/ha and the highest marginal rate of return of 6714.29%. Pavon − 76 treated with 0.75l/ha fungicide rate and planted on 10th July came in second with a net benefit of 301830 B/ha and a marginal rate of return of 5253.98%. Disease parameters like disease severity and the area under disease progress curves were negatively correlated with yield and yield components, whereas, yield components were positively correlated with yield. The farming communities should be trained or advised on the timely application of efficient fungicides against septoria trititci blotch which may lead to the utilization of an integrated disease management strategy.
RETRACTED: The Removal of Silica from water of Jordan Phosphate Mines Company using Nanofiltration
Authors: Hajarat Rasha A. , Slehat Jafar S. , Badwan Bayan M. , Ejelat Serena M. , El-Hashem Sewar , Alzedaneen Shatha A. 
Published: April 2024

Abstract

The authors have requested that this preprint be removed from Research Square.