bluuebunny/crossref_metadata_2025_split huggingface dataset:
Politeness, Power and Provocation: How Humour Functions in the Workplace
Authors: HOLMES JANET 
Published: March 2007

This article examines verbal humour in routine interactions within professional workplaces, using material recorded in four New Zealand government departments. The problem of defining humour is discussed, followed by a brief outline of the theoretical models which underpin the analysis of the various functions which humour serves in professional organizations. Humour can express positive affect in interaction. It can also facilitate or `licence' more negative interpersonal communicative intent. While politeness theory can account for the former, as a means of expressing collegiality at work, or de-emphasizing power imbalances, in its standard form politeness theory does not explain barbed, competitive or confrontational humour. For this it is necessary to look to `the dark side of politeness' (Austin, 1990). An alternative perspective thus examines the extent to which humour functions, especially in unequal encounters, as an acceptable strategy to help superiors maintain a position of power but also as a strategy used by subordinates to licence challenges to the power structures within which they operate, and as a legitimizing strategy in attempts at subverting the repressive or coercive discourse of superiors.
The Language of Ambiguity
Authors: HE AGNES WEIYUN 
Published: March 2007

This article explores communicative processes in Chinese involving Chinese American children in order to explain the notion of preference for ambiguity, a characteristic often invoked when describing the Chinese as a group. It also speculates on the impact this notion has on children's socialization. Preference for ambiguity can be defined as making ambiguous something that is otherwise clear-communicating ambiguously or conveying something that is ambiguous-communicating ambiguity. Treating ambiguity as an interaction-centered and activity-bound phenomenon rather than a purely semantic or logical problem, this article locates ambiguity in the intersubjectivity co-constructed by all participants and explores its role in the construction of cultural, situational and interpersonal contexts. It shows that ambiguity is shaped not only by lexico-grammar but also by discourse structure. This article draws data from a total of 30 hours of audio/video recorded classroom interactions involving 4 teachers and about 35 students (age 4.5 to 9 years) in two Chinese Heritage Language Schools in the USA as well as from observations and interviews. In the classroom context, children are compelled to make speculations and draw inferences regarding their interlocutors' references, intentions, dispositions and goals. They do so without confronting their interlocutors or holding their interlocutors accountable. In contrast, teachers freely and vocally (re-)formulate, clarify, question and interpret children's utterances in an effort to make the children's stances unequivocal. This study suggests that the communicative patterns observed with respect to ambiguity may play an important part in the socialization of cultural knowledge and cognitive styles.
Air Ring Selection for Blown Packaging Film
Authors: Dowd Laurence E. 
Published: March 2007

Blown film air rings are used primarily to stabilize the bubble and secondarily to cool the melt. They can affect maximum output, size range, or blow up ratio (BUR), gauge uniformity and range, optical properties and strength properties. We have evaluated nine air rings for performance in production of general purpose clarity and high molecular weight, low density polyethylene (HMW LDPE) packag ing film. We find that selection of an air ring can affect the balance of optical and physical properties. We evaluated the air rings with five different resins, and found that the selection of an air ring should depend upon the resin to be used, and the properties to be emphasized.
Aerogel‐To‐Sol‐To‐Aerogel (ASA) Process for Recycling, Repairing, Reprogramming of High‐Performance Organic Aerogels
Authors: Wang Changlin , Eisenreich Fabian , Tomović Željko 
Published: March 2024

AbstractWith rising energy demands and costs, the significance of thermally insulating materials is on a constant upward trajectory. While they offer impressive performance, their sustainability is increasingly becoming an essential design feature. The study thus develops an unprecedented strategy that enables recycling, repairing, and reprogramming of superinsulating polyimine aerogels. The principle at play involves the decomposition of polyimine aerogels into a solution of oligomers through transimination reactions with additional amines. This solution can be utilized to create new aerogels with virtually identical properties to the original ones. This aerogel‐to‐sol‐to‐aerogel (ASA) process is also applicable to mixed waste streams and damaged aerogels. Moreover, this method allows to alter the aerogel properties post‐synthetically through careful selection of amines. Since the ASA process is highly reproducible and selective, omits purification steps, and conserves 100% of the initially embedded chemical resources, it presents an innovative tool for the sustainable management of superinsulating aerogels.
An In Situ Near‐Surface Reconstruction Strategy Endowing Lithium‐Rich Oxides with Li/O Dual Vacancies and Spinel‐Carbon Dual Coating Layers Toward High Energy Density Cathode
Authors: Ouyang Yuguo , Zhang Ying , Wang Gongrui , Wei Xiaofei , Zhang Anping , Sun Junwei , Wei Shiqiang , Song Li , Dai Fangna , Wu Zhong‐Shuai 
Published: March 2024

AbstractLi‐rich cathode materials (LRMs) are regarded as the key cathode candidates for next‐generation lithium‐ion batteries(LIBs) because of their high specific capacity and environmental friendliness. However, LRMs encounter poor cyclability and low initial coulombic efficiency (ICE) hindering their practical application. Herein, a general near‐surface in situ reconstruction strategy is proposed of constructing the Li/O dual vacancies and spinel‐carbon dual coating layers on the surface of LRMs concurrently to improve Li+ storage performance. The as‐prepared LRMs exhibit a greatly strengthened specific capacity of 283 mAh g−1 with an enhanced ICE of 94% and long‐term cyclability of 91% retention after 200 cycles compared with the pristine LRMs (212 mAh g−1 with an ICE of 65%, 76% retention after 200 cycles). Furthermore, it is theoretically revealed that O vacancies (Ov) prefer to occur at the interface of the C2/m and Rm phases to mitigate lattice stress, rather the O sites in individual C2/m or Rm phase with more coordinated atoms. Besides, Li ions exhibit lower migration energy from C2/m phase to Rm phase with the Ov located at the lattice interface. Therefore, this strategy opens a new avenue in the design perspective of the LRMs’ near‐surface for high‐energy‐density LIBs.
The H2O2 Self‐Sufficient 3D Printed β‐TCP Scaffolds with Synergistic Anti‐Tumor Effect and Reinforced Osseointegration
Authors: Wang Qing , Chiu Chingyen , Zhang Hang , Wang Xuan , Chen Yanzheng , Li Xiang , Pan Jinsong 
Published: March 2024

AbstractTumor recurrence and massive bone defects are two critical challenges for postoperative treatment of oral and maxillofacial tumor, posing serious threats to the health of patients. Herein, in order to eliminate residual tumor cells and promote osteogenesis simultaneously, the hydrogen peroxide (H2O2) self‐sufficient TCP‐PDA‐CaO2‐CeO2 (TPCC) scaffolds are designed by preparing CaO2 or/and CeO2 nanoparticles (NPs)/chitosan solution and modifying the NPs into polydopamine (PDA)‐modified 3D printed TCP scaffolds by rotary coating method. CaO2 NPs loaded on the scaffolds can release Ca2+ and sufficient H2O2 in the acidic tumor microenvironment (TME). The generated H2O2 can further produce hydroxyl radicals (·OH) under catalysis effect by peroxidase (POD) activity of CeO2 NPs, in which the photothermal effect of the PDA coating enhances its POD catalytic effect. Overall, NPs loaded on the scaffold chemically achieve a cascade reaction of H2O2 self‐sufficiency and ·OH production, while functionally achieving synergistic effects on anti‐tumor and bone promotion. In vitro and in vivo studies show that the scaffolds exhibit effective osteo‐inductivity, induced osteoblast differentiation and promote osseointegration. Therefore, the multifunctional composite scaffolds not only validate the concept of chemo‐dynamic therapy (CDT) cascade therapy, but also provide a promising clinical strategy for postoperative treatment of oral and maxillofacial tumor.
Hierarchically Biomimetic Scaffolds with Anisotropic Micropores and Nanotopological Patterns to Promote Bone Regeneration via Geometric Modulation
Authors: Wei Xin , Chen Jiaxin , Shen Hui‐Yuan , Jiang Kai , Ren Haohao , Liu Yao , Luo En , Zhang Jin , Xu Jia‐Zhuang , Li Zhong‐Ming 
Published: March 2024

AbstractStructural engineering is an appealing means to modulate osteogenesis without the intervention of exogenous cells or therapeutic agents. In this work, a novel 3D scaffold with anisotropic micropores and nanotopographical patterns is developed. Scaffolds with oriented pores are fabricated via the selective extraction of water‐soluble polyethylene oxide from its poly(ε‐caprolactone) co‐continuous mixture and uniaxial stretching. The plate apatite‐like lamellae are subsequently hatched on the pore walls through surface‐induced epitaxial crystallization. Such a unique geometric architecture yields a synergistic effect on the osteogenic capability. The prepared scaffold leads to a 19.2% and 128.0% increase in the alkaline phosphatase activity of rat bone mesenchymal stem cells compared to that of the scaffolds with only oriented pores and only nanotopographical patterns, respectively. It also induces the greatest upregulation of osteogenic‐related gene expression in vitro. The cranial defect repair results demonstrate that the prepared scaffold effectively promotes new bone regeneration, as indicated by a 350% increase in collagen I expression in vivo compared to the isotropic porous scaffold without surface nanotopology after implantation for 14 weeks. Overall, this work provides geometric motifs for the transduction of biophysical cues in 3D porous scaffolds, which is a promising option for tissue engineering applications.
Versatile Mechanically Tunable Hydrogels for Therapeutic Delivery Applications
Authors: Sun Qiyao , Tao Siyuan , Bovone Giovanni , Han Garam , Deshmukh Dhananjay , Tibbitt Mark W. , Ren Qun , Bertsch Pascal , Siqueira Gilberto , Fischer Peter 
Published: March 2024

AbstractHydrogels provide a versatile platform for biomedical material fabrication that can be structurally and mechanically fine‐tuned to various tissues and applications. Applications of hydrogels in biomedicine range from highly dynamic injectable hydrogels that can flow through syringe needles and maintain or recover their structure after extrusion to solid‐like wound‐healing patches that need to be stretchable while providing a selective physical barrier. In this study, a toolbox is designed using thermo‐responsive poly(N‐isopropylacrylamide) (PNIPAM) polymeric matrices and nanocelluloses as reinforcing agent to obtain biocompatible hydrogels with altering mechanical properties, from a liquid injectable to a solid‐like elastic hydrogel. The liquid hydrogels possess low viscosity and shear‐thinning properties at 25 °C, which allows facile injection at room temperature, while they become viscoelastic gels at body temperature. In contrast, the covalently cross‐linked solid‐like hydrogels exhibit enhanced viscoelasticity. The liquid hydrogels are biocompatible and are able to delay the in vitro release and maintain the bioactivity of model drugs. The antimicrobial agent loaded solid‐like hydrogels are effective against typical wound‐associated pathogens. This work presents a simple method of tuning hydrogel mechanical strength to easily adapt to applications in different soft tissues and broaden the potential of renewable bio‐nanoparticles in hybrid biomaterials with controlled drug release capabilities.
The Combination of Membrane Disruption and FtsZ Targeting by a Chemotherapeutic Hydrogel Synergistically Combats Pathogens Infections
Authors: Wei Xianyuan , Guo Jintong , Geng Xiaorui , Xue Bin , Huang Shaohui , Yuan Zhen 
Published: March 2024

AbstractThe emergence of multidrug‐resistant (MDR) bacteria poses a significant challenge to global health. Due to a shortage of antibiotics, alternative therapeutic strategies are urgently needed. Unfortunately, colistin, the last‐resort antibiotic, has unavoidable nephrotoxicity and hepatotoxicity, and its single killing mechanism is prone to drug resistance. To address this challenge, a promising combinatorial approach that includes colistin, a membrane‐disrupting antimicrobial agent, and chelerythrine (CHE), a FtsZ protein inhibitor is proposed. This approach significantly reduces antibiotic dose and development of resistance, leading to almost complete inactivation of MDR pathogens in vitro. To address solubility issues and ensure transport, the antimicrobial hydrogel system LNP‐CHE‐CST@hydrogel, which induced reactive oxygen species (ROS) and apoptosis‐like cell death by targeting the FtsZ protein, is used. In an in vivo mouse skin infection model, the combination therapy effectively eliminated MDR bacteria within 24 h, as monitored by fluorescence tracking. The findings demonstrate a promising approach for developing multifunctional hydrogels to combat MDR bacterial infections.
Manipulating Stacking Fault Energy to Achieve Crack Inhibition and Superior Strength–Ductility Synergy in an Additively Manufactured High‐Entropy Alloy
Authors: Niu Pengda , Li Ruidi , Gan Kefu , Fan Zhiqi , Yuan Tiechui , Han Changjun 
Published: March 2024

AbstractAdditive manufacturing (AM) is a revolutionary technology that heralds a new era in metal processing, yet the quality of AM‐produced parts is inevitably compromised by cracking induced by severe residual stress. In this study, a novel approach is presented to inhibit cracks and enhance the mechanical performances of AM‐produced alloys by manipulating stacking fault energy (SFE). A high‐entropy alloy (HEA) based on an equimolar FeCoCrNi composition is selected as the prototype material due to the presence of microcracks during laser powder bed fusion (LPBF) AM process. Introducing a small amount (≈2.4 at%) of Al doping can effectively lower SFE and yield the formation of multiscale microstructures that efficiently dissipate thermal stress during LPBF processing. Distinct from the Al‐free HEA containing visible microcracks, the Al‐doped HEA (Al0.1CoCrFeNi) is crack free and demonstrates ≈55% improvement in elongation without compromising tensile strength. Additionally, the lowered SFE enhances the resistance to crack propagation, thereby improving the durability of AM‐printed products. By manipulating SFE, the thermal cycle‐induced stress during the printing process can be effectively consumed via stacking faults formation, and the proposed strategy offers novel insights into the development of crack‐free alloys with superior strength–ductility synergy for intricate structural applications.
Musculoskeletal Organs‐on‐Chips: An Emerging Platform for Studying the Nanotechnology–Biology Interface
Authors: Wang Yuwen , Yung Patrick , Lu Gang , Liu Yuwei , Ding Changhai , Mao Chuanbin , Li Zhong Alan , Tuan Rocky S. 
Published: March 2024

AbstractNanotechnology‐based approaches are promising for the treatment of musculoskeletal (MSK) disorders, which present significant clinical burdens and challenges, but their clinical translation requires a deep understanding of the complex interplay between nanotechnology and MSK biology. Organ‐on‐a‐chip (OoC) systems have emerged as an innovative and versatile microphysiological platform to replicate the dynamics of tissue microenvironment for studying nanotechnology–biology interactions. This review first covers recent advances and applications of MSK OoCs and their ability to mimic the biophysical and biochemical stimuli encountered by MSK tissues. Next, by integrating nanotechnology into MSK OoCs, cellular responses and tissue behaviors may be investigated by precisely controlling and manipulating the nanoscale environment. Analysis of MSK disease mechanisms, particularly bone, joint, and muscle tissue degeneration, and drug screening and development of personalized medicine may be greatly facilitated using MSK OoCs. Finally, future challenges and directions are outlined for the field, including advanced sensing technologies, integration of immune‐active components, and enhancement of biomimetic functionality. By highlighting the emerging applications of MSK OoCs, this review aims to advance the understanding of the intricate nanotechnology–MSK biology interface and its significance in MSK disease management, and the development of innovative and personalized therapeutic and interventional strategies.
Recent Progress in Haloalkene Synthesis by Hydrohalogenation (HX=HCl, HBr, HI) of Alkynes
Authors: Iwai Kento , Nishiwaki Nagatoshi 
Published: March 2024

AbstractHydrohalogenation of alkynes is one of the fundamental reactions in organic chemistry, as described in textbooks that begins from old time as Reppe's chemistry. This method, which directly affords haloalkenes in a single step, is attractive from both industrial and academic viewpoints. Despite the long history of this reaction, novel efficient catalysts and regioselective and/or stereoselective controlled reactions are still a challenging topic. This review addresses the recent (past decade) advances in this field of organic chemistry.
Multi‐Dimensional Bionic Micro‐Nanostructure Surface for Controllable Fog Harvesting: from Fabrication to Application
Authors: Pei Wenle , Wang Jianmei , Li Xueyan , Li Yan , Ning Ke , Wang Jun , Zhang Qiuya 
Published: March 2024

AbstractWith the rapid growth of the population and the development of the economy, the shortage of freshwater resources has become a worldwide problem. Utilizing fog harvesting provides a practical solution to relieve the water shortage problem for residents in arid regions. This review summarizes the typical fog harvesting phenomena in nature in detail, the construction methods, fog harvesting performance, and the action mechanism of different biomimetic micro‐nano structures from one‐dimensional (1D), two‐dimensional (2D), and three‐dimensional (3D) perspectives. The influence of surface micro‐nano structure and wettability on water harvesting performance is analyzed. Finally, the challenges and future development directions of multi‐scale micro‐nano surface controllable water harvesting technology are summarized and prospected, which provides a good idea for the design of bioinspired micro‐nanomaterials and promotes water harvesting from scientific research to practical application.
Strong Metal‐Support Interaction‐Induced Regulation of Hydrogen Adsorption Behavior of Uniform Ru Nanoparticles Integrated with CoP Nanosheets for High‐Efficiency Electrochemical Hydrogen Production
Authors: Zhu Yufeng , Li Jing , Zhou Guangyao , Qian Leiming , Fang Yu , Xu Mingjiang , Pang Huan , Zhang Mingyi , Xu Jianping , Yang Jun , Xu Lin , Tang Yawen 
Published: March 2024

AbstractThe ingenious modification of the hydrogen adsorption state of ruthenium (Ru) for achieving high‐efficiency electrocatalytic performance is of vital importance for water electrolysis technology. Herein, a novel heterostructured catalyst composed of highly dispersed ultrafine Ru nanoparticles immobilized on CoP nanosheet (denoted as Ru/CoP hereafter) is developed through a feasible “impregnation‐phosphorization” strategy. Experimental results and density functional theory (DFT) simulations collectively indicate that the strong metal‐support interaction (SMSI) effect between Ru nanoparticles and CoP nanosheet substrate can dramatically tailor the electronic configurations of active centers, thus accelerating the charge transfer rate and regulating the hydrogen binding energy. Consequently, the Ru/CoP electrocatalyst with optimal Ru loading content demonstrates prominent HER performance in alkaline solution with a low overpotential of 36 mV to afford a current density of 10 mA cm−2 and a small Tafel slope of 73.0 mV dec−1, which can almost compete with that of commercial Pt/C. This work provides a new inspiration for the elaborate modification of intermediate adsorption capacity and enhancement of electrocatalytic performance for high‐efficiency electrocatalysts in energy conversion fields.
Charging Ahead: Examining the Future Therapeutic Potential of Electroceuticals
Authors: Balasubramanian Swarnalatha , Weston David A. , Levin Michael , Davidian Devon Charles Cardoso 
Published: March 2024

AbstractElectroceuticals derived from electronic and pharmaceuticals is a term coined to describe the therapeutic manipulation of neuronal signaling. In recent years, the complexity and range of applications of electroceuticals have grown considerably. Therefore, here a revised ontology and framework for defining electroceuticals that broadens the concept beyond neuron‐targeted interventions is suggested. This more inclusive framework aims to provide greater coherence and bring together different stakeholders to accelerate progress in this field. It is suggested that electroceuticals can be categorized according to the level of physiology for which they act: cellular, tissue, organ, and systemic. Emerging developments for each category of electroceuticals and future directions are discussed from a pharmaceutical industry perspective. Potential challenges are highlighted for translation of electroceuticals, such as a lack of clinical biomarkers and incomplete understanding of mechanisms of action and offer solutions for stimulating progress in this exciting field.
Manipulation of Glutamatergic Neuronal Activity in the Primary Motor Cortex Regulates Cardiac Function in Normal and Myocardial Infarction Mice
Authors: Bo Wenyan , Cai Mengxin , Ma Yixuan , Di Lingyun , Geng Yanbin , Li Hangzhuo , Tang Caicai , Tai Fadao , He Zhixiong , Tian Zhenjun 
Published: March 2024

AbstractCardiac function is under neural regulation; however, brain regions in the cerebral cortex responsible for regulating cardiac function remain elusive. In this study, retrograde trans‐synaptic viral tracing is used from the heart to identify a specific population of the excitatory neurons in the primary motor cortex (M1) that influences cardiac function in mice. Optogenetic activation of M1 glutamatergic neurons increases heart rate, ejection fraction, and blood pressure. By contrast, inhibition of M1 glutamatergic neurons decreased cardiac function and blood pressure as well as tyrosine hydroxylase (TH) expression in the heart. Using viral tracing and optogenetics, the median raphe nucleus (MnR) is identified as one of the key relay brain regions in the circuit from M1 that affect cardiac function. Then, a mouse model of cardiac injury is established caused by myocardial infarction (MI), in which optogenetic activation of M1 glutamatergic neurons impaired cardiac function in MI mice. Moreover, ablation of M1 neurons decreased the levels of norepinephrine and cardiac TH expression, and enhanced cardiac function in MI mice. These findings establish that the M1 neurons involved in the regulation of cardiac function and blood pressure. They also help the understanding of the neural mechanisms underlying cardiovascular regulation.