bluuebunny/crossref_metadata_2025_split huggingface dataset:
Long range behavior of high‐rank topological multipole moments
Authors: Rafat Michel , Popelier Paul L. A. 
Published: January 2007

AbstractThe construction of a high‐rank multipolar force field (for peptides) is a complex task, leading to several intermediate questions in need of a clear answer. Here we focus on the convergence of the (electrostatic) multipolar expansion at medium and long range. Using molecular electron densities, quantum chemical topology (QCT) defines the atoms as finite volumes, each endowed with multipole moments. The terms in the multipole expansion are grouped according to powers of the internuclear distance,R−L. Given two atom types at a given distance, we determine which rank (L) is necessary for the electrostatic energy to converge to the exact interaction energy within a certain error. With this information, the rank of the expansion for each interaction can be adapted to the required accuracy and the available computing power. © 2007 Wiley Periodicals, Inc. J Comput Chem 28: 832–838, 2007
Identification of proteins directly from tissue: in situ tryptic digestions coupled with imaging mass spectrometry
Authors: Groseclose M. Reid , Andersson Malin , Hardesty William M. , Caprioli Richard M. 
Published: January 2007

AbstractA novel method for on‐tissue identification of proteins in spatially discrete regions is described using tryptic digestion followed by matrix‐assisted laser desorption/ionization (MALDI) imaging mass spectrometry (IMS) with MS/MS analysis. IMS is first used to reveal the protein and peptide spatial distribution in a tissue section and then a serial section is robotically spotted with small volumes of trypsin solution to carry out in situ protease digestion. After hydrolysis, 2,5‐Dihydroxybenzoic acid (DHB) matrix solution is applied to the digested spots, with subsequent analysis by IMS to reveal the spatial distribution of the various tryptic fragments. Sequence determination of the tryptic fragments is performed using on‐tissue MALDI MS/MS analysis directly from the individual digest spots. This protocol enables protein identification directly from tissue while preserving the spatial integrity of the tissue sample. The procedure is demonstrated with the identification of several proteins in the coronal sections of a rat brain. Copyright © 2007 John Wiley & Sons, Ltd.
Retropubic versus perineal radical prostatectomy in early prostate cancer: Eight‐year experience
Authors: Martis Gianni , Diana Massimo , Ombres Maurizio , Cardi Antonio , Mastrangeli Roberta , Mastrangeli Bruno 
Published: January 2007

AbstractBackgroundProstate cancer is the most common malignancy in men and the second leading cause of cancer death. A randomized study was performed on patients with localized prostate cancer and treated with radical prostatectomy using the perineal or the retropubic approach comparing oncological outcomes, cancer control, and functional results.Study DesignBetween 1997 and 2004, in a randomized study 200 patients underwent a radical prostatectomy performed by retropubic (100 patients) or perineal (100 patients) approach.ResultsDifferences between hospital stay, duration of catheter drainage, intraoperative blood loss, and transfusion requirements were statistically significant in favor of perineal prostatectomy. Differences between positive surgical margins and urinary continence in the two groups were not statistically significant at 6 and 24 months. Differences between erectile function at 24 months were statistically significant in favor of retropubic prostatectomy.ConclusionsRadical perineal prostatectomy is an excellent alternative approach for radical surgery in the treatment of early prostate cancer. J. Surg. Oncol. 2007; 95: 513–518. © 2007 Wiley‐Liss, Inc.
The case for routine use of adjuvant therapy in pancreatic cancer
Authors: Kennedy Eugene P. , Yeo Charles J. 
Published: January 2007

AbstractPancreatic cancer is a devastating disease with a poor prognosis for most patients. Surgical resection remains the cornerstone of treatment, providing the only realistic hope of long‐term survival. Even with optimal surgical management, 5‐year survival averages 15% to 20% for resectable disease. Progress is being made, however. Currently, the benefits of postoperative therapy for resected pancreatic ductal adenocarcinoma appear clear, and recommendations for such therapy appear to us to be well justified. Additional benefit to patients awaits the development of new agents, molecular targeted drugs, and novel approaches such as immunotherapy. J. Surg. Oncol. 2007;95:597–603. © 2007 Wiley‐Liss, Inc.
A simple method to accurately position Port‐A‐Cath without the aid of intraoperative fluoroscopy or other localizing devices
Authors: Horng Huann‐Cheng , Yuan Chiou‐Chung , Chao Kuan‐Chong , Cheng Ming‐Huei , Wang Peng‐Hui 
Published: January 2007

AbstractBackgroundTo evaluate the efficacy and acceptability of the Port‐A‐Cath (PAC) insertion method with (conventional group as II) and without (modified group as I) the aid of intraoperative fluoroscopy or other localizing devices.MethodsA total of 158 women with various kinds of gynecological cancers warranting PAC insertion (n = 86 in group I and n = 72 in group II, respectively) were evaluated. Data for analyses included patient age, main disease, dislocation site, surgical time, complications, and catheter outcome.ResultsThere was no statistical difference between the two groups in terms of age, main disease, complications, and the experiencing of patent catheters. However, appropriate positioning (100% in group I, and 82% in group II) in the superior vena cava (SVC) showed statistical differences between the two groups (P = 0.001). In addition, the surgical time in group I was statistically shorter than that in group II (P < 0.001).ConclusionsThe modified method for inserting the PAC offered the following benefits: including avoiding X‐ray exposure for both the operator and the patient, defining the appropriate position in the SVC, and less surgical time. J. Surg. Oncol. 2007;95:582–586. © 2007 Wiley‐Liss, Inc.
Health‐care product advertising: The influences of message framing and perceived product characteristics
Authors: Chang Chun‐Tuan 
Published: January 2007

AbstractMessage framing readily lends itself to marketing communication and advertising persuasion strategies. However, past research yields contradictory and inconsistent predictions as to whether positive or negative frames are more persuasive. This study examines the most appropriate message framing to present to consumers in print advertisements for health care products. Two experimental studies are conducted to investigate the moderating effects of product functions: perceived innovativeness and perceived risk on the processing of framed advertising messages. Findings of Study 1 indicate that messages for familiar products should be framed differently depending on perceived product functions (prevention vs. detection), but gain‐framed messages are more persuasive for both new prevention and detection products. Results of Study 2 suggest that a mixed‐framed message (combining gain and loss) could enhance message effectiveness only when subjects have prior experience. Similar to the role of product function, product perceived risk is found to moderate the framing effects on message effectiveness. © 2007 Wiley Periodicals, Inc.
Hysterical chorea: Report of an outbreak and movie documentation by Arthur Van Gehuchten (1861–1914)
Authors: Giménez‐Roldán Santiago , Aubert Geneviève 
Published: January 2007

AbstractPsychogenic movement disorders remain a frequent and important clinical problem. First described in the Middle Ages, the dancing mania is considered to be one form of mass hysteria characterized by outbreaks of collective movement disorders. Patients may exhibit a wide variety of movement and gait disturbances, including tremulousness, jerks, or convulsions, usually with a sudden onset. Arthur Van Gehuchten (1861–1914), a distinguished Belgian neuroanatomist and neurologist, reported an outbreak of sudden involuntary movements in 13 adolescent girls residing in an orphanage. The description is to be found in his book Les Maladies nerveuses, completed before 1914 and published posthumously in 1920. The chapter is illustrated with sequential photographs of a girl exhibiting a peculiar gait, which is descriptively referred to as “chorée salutatoire” (saluting chorea). The original film with these pictures has been retrieved and is presented here together with a very similar film excerpt also found in Van Gehuchten's film collection. Van Gehuchten's movie documentation of a psychogenic movement disorder—labeled chorea but which should probably be considered as dystonia according to contemporary classification—appears to be unique. This report illustrates the tremendous value of moving pictures in recording and analyzing movement disorders. © 2006 Movement Disorder Society
Structural white matter abnormalities in patients with idiopathic dystonia
Authors: Bonilha Leonardo , de Vries Paulien M. , Vincent Diana J. , Rorden Chris , Morgan Paul S. , Hurd Mark W. , Besenski Nada , Bergmann Kenneth J. , Hinson Vanessa K. 
Published: January 2007

AbstractWe investigated whether structural white matter abnormalities, in the form of disruption of axonal coherence and integrity as measured with diffusion tensor imaging (DTI), constitute an underlying pathological mechanism of idiopathic dystonia (ID), independent of genotype status. We studied seven subjects with ID: all had cervical dystonia as their main symptom (one patient also had spasmodic dysphonia and two patients had concurrent generalized dystonia, both DYT1‐negative). We compared DTI MR images of patients with 10 controls, evaluating differences in mean diffusivity (MD) and fractional anisotropy (FA). ID was associated with increased FA values in the thalamus and adjacent white matter, and in the white matter underlying the middle frontal gyrus. ID was also associated with increase in MD in adjacent white matter to the pallidum and putamen bilaterally, left caudate, and in subcortical hemispheric regions, including the postcentral gyrus. Abnormal FA and MD in patients with ID indicate that abnormal axonal coherence and integrity contribute to the pathophysiology of dystonia. These findings suggest that ID is not only a functional disorder, but also associated with structural brain changes. Impaired connectivity and disrupted flow of information may contribute to the impairment of motor planning and regulation in dystonia. © 2006 Movement Disorder Society
Punding prevalence in Parkinson's disease
Authors: Miyasaki Janis M. , Al Hassan Khalid , Lang Anthony E. , Voon Valerie 
Published: January 2007

AbstractThe purpose of this study was to determine punding prevalence in an ambulatory Parkinson's disease (PD) population. We conducted a patient‐and‐caregiver–completed punding survey in 373 consecutive patients in an academic ambulatory center. Completion rate was 78%. Only four patients were identified as punding. Patients did not retain insight to their behavior. Forty patients with high‐dose levodopa monotherapy or levodopa and dopamine agonist treatment had physician‐administered interview. None had punding. Punding incidence was low in this patient group (1.4%) in contrast with previous reports of 14%. Despite the low incidence, this behavior is disruptive and should be carefully elicited by physicians caring for Parkinson's disease patients. © 2006 Movement Disorder Society
Selective diplopia in Parkinson's disease: A special subtype of visual hallucination?
Authors: Nebe Angelika , Ebersbach Georg 
Published: January 2007

AbstractDiplopia is sometimes reported by patients with Parkinson's disease (PD) without apparent oculomotor disorders. We assessed clinical features and associated oculomotor and perceptual performance in 14 patients (6 male, 8 female) with PD with a peculiar type of selective diplopia. Duplication of images was confined to single objects or persons, occurred repetitively, and lasted few seconds in all subjects. Frequency of episodes ranged from several episodes per day to three episodes per year. In six of seven subjects undergoing comprehensive ophtalmological examination, subtle ocular disorders (heterophoria, strabism, etc.) were found. Nine of 14 patients were suffering from current or previous visual hallucinations and 3 more patients developed hallucinations within 3 years of diplopia onset. Selective diplopia of isolated single objects and persons in PD is possibly related to hallucinosis and minor ocular disturbances seem to be a triggering factor for this peculiar type of misperception. © 2006 Movement Disorder Society
Normal cardiovascular reflex testing in patients with parkin disease
Authors: Del Sorbo Francesca , Elia Antonio E. , De Joanna Gabriella , Romito Luigi M. , Garavaglia Barbara , Albanese Alberto 
Published: January 2007

AbstractThe objective of this study was to investigate cardiovascular autonomic function in patients with parkin disease. Ten patients with a genetically confirmed diagnosis were compared to 11 healthy controls. Symptoms related to autonomic dysfunction were collected by structured interviews. Cardiovascular autonomic reflex function was evaluated using a standard battery of eight tests. Autonomic tests included the study of sympathetic function through the analysis of blood pressure responses to head‐up tilt, standing, isometric hand grip, cold pressor, mental arithmetic, Valsalva maneuver (Valsalva overshoot), and the study of parasympathetic function through the analysis of heart rate responses to deep breathing, hyperventilation, and Valsalva ratio. Seven out of 10 patients reported symptoms involving different aspects of autonomic function, while 5 out of 11 controls reported symptoms related exclusively to orthostatic dizziness and constipation. Symptoms related to bladder dysfunction were the most frequent autonomic abnormality occurring in six patients, followed by orthostatic dizziness and dry mouth (in four patients each). Constipation occurred in three patients, sialorrhea in two, and erectile dysfunction, dry eye, and warm intolerance in one each. Cardiovascular reflex testing revealed no difference between patients and controls in quantitative assessment of both sympathetic and parasympathetic functions, except for diastolic blood pressure after isometric hand grip that did not increase normally in parkin patients compared to controls (P = 0.007). These data show that cardiovascular dysautonomia is not associated to the parkin phenotype, whereas urinary complaints are more frequently reported by parkin patients than by controls. Urinary dysautonomia warrants further investigation in patients with parkin disease. © 2006 Movement Disorder Society
Data protection in biomaterial banks for Parkinson's disease research: The model of GEPARD (Gene bank Parkinson's Disease Germany)
Authors: Eggert Karla , Wüllner Ullrich , Antony Gisela , Gasser Thomas , Janetzky Bernd , Klein Christine , Schöls Ludger , Oertel Wolfgang 
Published: January 2007

AbstractParkinson's disease (PD) is the second most common neurodegenerative disease. Although 10 gene loci have been identified to cause a Parkinsonian syndrome, these loci account only for a minority of PD patients. Large, systematic research programs are required to collect, store, and analyze DNA samples and clinical information to support further discovery of additional genetic components of PD or other movement disorders. Such programs facilitate research into the relationship between genotype and phenotype. The German Competence Network on Parkinson's disease (CNP) initiated the Gene Bank Parkinson's Disease Germany (GEPARD), providing an administrative and scientific infrastructure for the storage of DNA and clinical data that are electronically accessible and protective of patient rights. In this article, we offer guidance on how to establish a framework for a clinical genetic data and DNA bank, and describe GEPARD as a model that may be useful to other local, national, and international research groups developing similar programs. © 2006 Movement Disorder Society
Asymmetrical alien hands in corticobasal degeneration
Authors: FitzGerald David B. , Drago Valeria , Jeong Yong , Chang Yu‐Ling , White Keith D. , Heilman Kenneth M. 
Published: January 2007

AbstractThere are several forms of alien limb, but alien limb in corticobasal degeneration (CBD) is not well understood. We studied a patient with CBD who demonstrated two different types of alien limb. With his right hand he demonstrated a tactile avoidance response with levitation. With his left hand, he demonstrated continuous tactile pursuit of the examiner's hand (“tactile mitgehen”). Mitgehen is often associated with frontal dysfunction, but avoidance response and levitation are often associated with parietal dysfunction. © 2006 Movement Disorder Society
Celiac disease presenting with motor neuropathy: Effect of gluten free‐diet
Authors: Rigamonti Andrea , Magi Stefania , Venturini Elisabetta , Morandi Lucia , Ciano Claudia , Lauria Giuseppe 
Published: January 2007

AbstractCeliac disease is a rare cause of neuropathy that most commonly presents with symmetric distal sensory disturbances. We describe two patients with celiac disease in whom neuropathy presented unusually with progressive weakness of the limbs. In both patients a gluten‐free diet induced a significant improvement of muscle strength and neurophysiological abnormalities, suggesting a direct pathogenetic role of sensitivity to gluten. Celiac disease should be considered in patients with idiopathic neuropathy even when gastrointestinal symptoms are absent. Muscle Nerve, 2007
Kurtosis correction method for X̄ and R control charts for long‐tailed symmetrical distributions
Authors: Tadikamalla Pandu R. , Popescu Dana G. 
Published: January 2007

AbstractThis paper proposes a kurtosis correction (KC) method for constructing the X̄ and R control charts for symmetrical long‐tailed (leptokurtic) distributions. The control charts are similar to the Shewhart control charts and are very easy to use. The control limits are derived based on the degree of kurtosis estimated from the actual (subgroup) data. It is assumed that the underlying quality characteristic is symmetrically distributed and no other distributional and/or parameter assumptions are made. The control chart constants are tabulated and the performance of these charts is compared with that of the Shewhart control charts. For the case of the logistic distribution, the exact control limits are derived and are compared with the KC method and the Shewhart method. © 2007 Wiley Periodicals, Inc. Naval Research Logistics, 2007
Dynamic stability of a porous cylindrical shell
Authors: Belica Tomasz , Magnucki Krzysztof 
Published: January 2007

AbstractThis paper is devoted to a closed cylindrical shell made of a porous‐cellular material. The mechanical properties vary continuously on the thickness of a shell. The mechanical model of porosity is as described as presented by Magnucki, Stasiewicz. A shell is simply supported on edges. On the ground of assumed displacement functions the deformation of shell is defined. The displacement field of any cross section and linear geometrical and physical relationships are assumed in cylindrical coordinate system. The components of deformation and stress state were found. Using the Hamilton's principle the system of differential equations of dynamic stability is obtained. The forms of unknown functions are assumed and the system of a differential equations is reduced to a simple ordinary equation of dynamic stability of shell (Mathieu's equation). The derived equation are used for solving a problem of dynamic stability of porous‐cellular shell with intensity of load directed in generators of shell. The critical loads are derived for a family of porous shells. The unstable space of family porous shells is found. The influence a coefficient of porosity on the stability regions in Figures is presented. The results obtained for porous shell are compared to a homogeneous isotropic cylindrical shell. (© 2006 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
Numerical simulation of crack–propagation in shells
Authors: Hoppe Ulrich , Hackl Klaus 
Published: January 2007

AbstractWe develop a finite element method for the simulation of fragmentation of thin shells. The method is valid for completely non–linear problems, but is restricted to through–the–thickness cracks, which are normal to the midsurface. The methodology is based on the extended finite element method (X–FEM). The use of X–FEM allows arbitrary crack path evolution and does not require a priori knowledge of the crack zone or remeshing. (© 2006 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
Influence of the contact model on the onset of sprag‐slip
Authors: Keitzel Hanna , Hoffmann Norbert 
Published: January 2007

AbstractIn systems with sliding‐friction often strong self‐excited vibrations do occur. One of the possible underlying mechanisms is the so‐called sprag‐slip instability. In the present work the onset of sprag‐slip is investigated by a simple model in which an inclined elastic beam slides over a rigid belt moving with constant velocity. For a Coulomb friction law and a contact model with constant contact stiffness for a certain range of parameters the system loses its static solution corresponding to the steady sliding state. Simultaneously with this loss of existence of the static solution the qualitative properties of the system's flow field in phase space change, resembling a transition from stable to unstable behavior. To investigate the influence of contact models and related parameters on the details of this onset of sprag‐slip also Hertz theory of elastic contact is applied. (© 2006 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
The elastic response for microlayered functionally graded media
Authors: Jȩdrysiak J. , Wierzbicki E. , Woźniak Cz. 
Published: January 2007

AbstractIn this note microlayered composites having continuously varying macroscopic properties are considered. Such composites are referred to as the functionally graded laminates (FGL). The aim of this contribution is to derive a new averaged model describing the elastic response of the FGL, using the modified tolerance averaging technique, developed for periodic composites and structures by Woźniak and Wierzbicki (2000). (© 2006 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
Cavities in a visco‐plastic material: A mesoscopic concept
Authors: Weinberg Kerstin , Böhme Thomas 
Published: January 2007

AbstractIn the present work we investigate the temporal development of arbitrarily distributed voids in a visco‐plastic material under different loading regimes. A mesoscopic continuum model is used in order to take the microstructure of the material into account. In particular, we introduce a mesoscopic space representing an extension of the space‐time domain of the continuum mechanical fields. This extended domain requires a reformulation of the classical balance equations as well as the consideration of additional constitutive quantities. Furthermore a mesoscopic distribution function can be introduced which follows an own balance. Assuming a special model of porous composites, the spherical shell model, all required steps are elaborated in order to describe load‐induced void‐growth in a metal‐like matrix. We conclude with some exemplary results which show astonishing similarities with co‐called LSW‐theories. (© 2006 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)