bluuebunny/crossref_metadata_2025_split huggingface dataset:
Carbon composites as an Avante garde material in mitigating dyes and heavy metal pollution
Authors: Palanisamy Suresh Babu 
Published: April 2024

Abstract
Depletion of potable water availability is threatening the whole biota, owing to the presence of anthropogenic compounds and hazardous chemicals above the permissible levels. Although many conventional methods exist, the development of innovative technologies is critical for wastewater treatment and recycling. Carbon composites have recently seen widespread use across a variety of industries due to their distinctive and superior properties. These carbon composites are easily integrated into many stages of the treatment process, making them efficient, cost-effective, and environmentally friendly. This chapter discusses the importance and effectiveness of carbon-based composite materials in removing toxic dyes and heavy metal contaminants from the environment. Carbon composites are classified according to their sources, preparation methods, and applications. This chapter also discusses various research perspectives on carbon composites, particularly from an environmental and financial standpoint.
Healthcare experiences of fibromyalgia patients and their associations with satisfaction and pain relief. A patient survey
Authors: Wigers Sigrid Hørven , Veierød Marit B. , Mengshoel Anne Marit , Forseth Karin Øien , Dahli Mina Piiksi , Juel Niels Gunnar , Natvig Bård 
Published: April 2024

Abstract

Objectives
The etiology of fibromyalgia (FM) is disputed, and there is no established cure. Quantitative data on how this may affect patients’ healthcare experiences are scarce. The present study aims to investigate FM patients’ pain-related healthcare experiences and explore factors associated with high satisfaction and pain relief.

Methods
An anonymous, online, and patient-administered survey was developed and distributed to members of the Norwegian Fibromyalgia Association. It addressed their pain-related healthcare experiences from both primary and specialist care. Odds ratios for healthcare satisfaction and pain relief were estimated by binary logistic regression. Directed acyclic graphs guided the multivariable analyses.

Results
The patients (n = 1,626, mean age: 51 years) were primarily women (95%) with a 21.8-year mean pain duration and 12.7 years in pain before diagnosis. One-third did not understand why they had pain, and 56.6% did not know how to get better. More than half had not received satisfactory information on their pain cause from a physician, and guidance on how to improve was reported below medium. Patients regretted a lack of medical specialized competence on muscle pain and reported many unmet needs, including regular follow-up and pain assessment. Physician-mediated pain relief was low, and guideline adherence was deficient. Only 14.8% were satisfied with non-physician health providers evaluating and treating their pain, and 21.5% were satisfied (46.9% dissatisfied) with their global pain-related healthcare. Patients’ knowledge of their condition, physicians’ pain competence and provision of information and guidance, agreement in explanations and advice, and the absence of unmet needs significantly increased the odds of both healthcare satisfaction and pain relief.

Conclusions
Our survey describes deficiencies in FM patients’ pain-related healthcare and suggests areas for improvement to increase healthcare satisfaction and pain relief. (REC# 2019/845, 09.05.19).
Reproductive Health in Trans and Gender Diverse Patients: Fertility related knowledge, attitudes, and decision-making among gender diverse youth – A narrative review
Authors: Baines Hayley K , Quinn Gwendolyn P , Chen Diane , Nahata Leena 
Published: April 2024

In brief
Transgender and gender diverse (TGD) youth demonstrate low utilization of fertility preservation before medical and surgical gender-affirming interventions. However, a significant number of TGD youth have goals for parenthood and/or recognize that their attitude toward future family-building goals may change over time. In this narrative review, we conclude that TGD young people should have ongoing opportunities to discuss their family-building goals and options for fertility preservation. Validated decision tools can help facilitate these discussions.

Abstract
The number of transgender and gender diverse (TGD) youth seeking care continues to increase, necessitating comprehensive counseling about potential long-term effects of gender-affirming medical interventions on fertility. The objective of this narrative review was to examine fertility-related knowledge, attitudes, and decision-making (including factors influencing decisions, decision regret, and decision tools) among TGD youth. We searched PubMed, PsycInfo, and Google Scholar for original, peer-reviewed research investigating TGD youth attitudes and knowledge of fertility and fertility preservation, perspectives on fertility counseling and fertility preservation decision-making, as well as fertility-related decision tools. We reviewed 106 studies; eight were included in this narrative review. Four studies assessed TGD youth knowledge and attitudes of fertility and fertility preservation, three examined perspectives on fertility counseling and fertility preservation decision-making, and three discussed development of decision tools. Key findings were that: (1) many TGD youth are aware of potential fertility-related impacts of gender-affirming treatments, but there are still unmet informational needs, (2) some TGD youth report an interest in future biological parenthood, and of those who are not currently interested in biological parenthood, many acknowledge their desires may change over time, (3) ongoing discussions about fertility and fertility preservation are critical, and (4) decision tools are in development. In conclusion, TGD youth and their caregivers should receive ongoing, comprehensive fertility counseling and decision tools may be helpful to facilitate these discussions and decisions in each youth’s gender-affirming care journey.
A complex methodology for the development of mathematical modeling skills in engineering education
Authors: Sipos Dóra , Kocsis Imre 
Published: April 2024

AbstractToday, the role of humans is changing rapidly in both industrial production activities and services. Mediocre, easy-to-learn activities can be performed more efficiently by machines; mediocre knowledge is being devalued while the importance of high-level skills is increasing. As a result, in all sectors of the economy, and especially in engineering, new approaches to expert training are needed; people must learn to hand over certain decision-making roles and to control the processes supported by AI rather than compete with it. STEM education has a responsibility to achieve these goals and must develop appropriate tools for engineering education. This paper presents a complex didactic methodology for competency-based education in engineering bachelor programs. An important element is the mathematical competency map, which shows the importance and place of mathematical and algorithmic (coding) knowledge in engineering topics. Another element is the systematic testing of mathematical knowledge in non-mathematical contexts in engineering courses. We provide an overview of our achievements in applying the developed toolset and improving the efficiency of mathematics teaching in engineering bachelor programs.
DNA-based diagnostics of hereditary diseases of the respiratory tract
Authors: Kutsev S. I. , Shchagina O. A. , Melyanovskaya Yu. L. , Kondratyeva E. I. 
Published: April 2024

The diagnosis of orphan lung diseases often requires specific tests, and treatment is difficult due to problems in understanding the mechanisms of disease development and low incidence. When a therapy is developed, it is very expensive.The aim of the article was to present modern approaches for the genetic diagnosis of hereditary respiratory diseases.Conclusion. A physician of any specialty can encounter an orphan disease in clinical practice. The emergence of new methods for the maintenance and targeted therapy of orphan lung diseases necessitates allertness of both pediatric and adult pulmonologists. Competent management of such patients requires knowledge of the basics of genetics and the modern possibilities of DNA diagnostics, as well as close interdisciplinary cooperation between physicians of different specialties and laboratories.
A new software for automated analysis of respiratory tract ciliary epithelium movement for the diagnosis of primary ciliary dyskinesia
Authors: Kyian T. A. , Smirnikhina S. A. , Demchenko A. G. , Veiko R. V. , Kondratyeva E. I. 
Published: April 2024

Primary ciliary dyskinesia (PCD) is a rare hereditary disease. In this ciliopathy, the disturbed structure and motility of the ciliary epithelium negatively affects the ciliary function and leads to prominent decrease or absence of mucociliary clearance. The European guidelines recommend analyzing the cilia beat frequency (СBF) in a native preparation or in ALI culture using light microscopy as one of the methods to confirm the diagnosis of PCD.The aim of this project was to create software for automated analysis of the movement/beating of the ciliary epithelium of the respiratory tract for the diagnosis of primary ciliary dyskinesia using digital high-speed video microscopy in vivo and in vitro.Methods. Five healthy donors and 10 patients with suspected PCD underwent nasal epithelial brush biopsy. The preparations were examined with a transmission electron microscope in vivo. Epithelial cells were also isolated from the nasal biopsy specimen, and ciliogenesis of these cells was performed by ALI-culturing, followed by digital high-speed video microscopy and assessment of the number of active cells and cilia beating frequency. The resulting video images were used to create the software.Results. Software for determination of ciliary epithelium beat frequency in primary ciliary dyskinesia (PCD HighSpeed Video Microscopy Analysis – PCD HSVMA) was created to optimize the diagnosis of PCD by light microscopy (software registration number 2023687245). The software is designed to count the number of active cells of ciliary epithelium and CBF (Hz) by digital high-speed video microscopy in vivo and in vitro in ALI-culture. PCD HSVMA software features storage of patient data, display of heat map, formation of a large server database of patients and video files, building of color and static histograms, processing of several areas in one video. Our software has a number of advantages over CiliarMove and Cilialyzer and has high correlation of CFB (Hz) estimation with these products.Conclusion. Our software can be used for improvement of PCD diagnostics in laboratories of healthcare institutions, in scientific institutions and can be included in specialist educational programs for laboratory doctors, pediatricians, general practitioners, pulmonologists, diagnosticians (endoscopists).
Congenital alveolar dysplasia and alveolar capillary dysplasia with misalignment of the pulmonary veins: clinical and anatomical comparisons
Authors: Ovsyannikov D. Yu. , Miroshnichenko V. P. , Davydov I. S. , Abrahamyan M. A. , Gorev V. V. , Talalaev A. G. , Semina Yu. I. , Strelnikova V. A. , Tumanova E. L. 
Published: April 2024

Congenital alveolar dysplasia (СAD) and alveolar capillary dysplasia with misalignment of the pulmonary veins (ACD/MPV) are rare genetically determined interstitial lung diseases in infants that manifest in the first hours to days after birth, have fatal outcome and are usually diagnosed at autopsy.The aim of this work was to consider the clinical manifestations and pathomorphologic picture of CAD and ACD/MPV based on clinical observations of newborns who were on a ventilator, received therapy for high pulmonary hypertension and extracorporeal membrane oxygenation (ECMO). The clinical characteristics and medical history of the patients are described. The results of lifetime imaging methods, autopsy examinations with light microscopy and the use of routine staining methods of micro-preparations as well as immunohistochemical methods are considered. Morphologic changes in the lungs characteristic of CAD and ACD/MPV are described in detail in the analysis of histologic examination data.Conclusion. The pathoanatomical examination data are of crucial importance for the diagnosis of CAD and ACD/MPV, which must be suspected in newborns with respiratory insufficiency and severe pulmonary hypertension when ventilation, inhalation of nitric oxide and ECMO are ineffective.
TAMAN BACA DI BANJARBARU
Authors: Mufidah Husnun Zahidatul , Wastuty Prima Widia 
Published: April 2024

Reading is one of the basic skills that must be mastered by everyone. However, the reading rate of people in Indonesia is very low. In fact, literacy conditions in Indonesia are now in crisis, which is also called a literacy emergency. Increasing interest in reading in the younger generation in Indonesia today is really important amidst so many technologies that are very rapidly developing. Therefore, Indonesia is currently so active at making movements to increase interest in reading. The purpose of this Community Library is to increase the reading interest of Indonesian people while providing adequate facilities for reading for the community. The design of Community Library uses architectural programming method. The process of this method is divided into two stages consisting of preparing a program that is an activity of analyzing data that led to architectural problems and designing designs that can solve problems. The digitalization of books can be used as a way to increase the children and adults interest in reading again. However, that still feels lacking, because it requires a more efficient steps that can further influence the interest in reading and attract the attention of the public to e interested in reading. One way to attract the reading interest of public to be interested in reading is to turn the library into a creative reading place. This is what underlies the thought of the Community Library. Creating a Community Library with the concept of Recreation Space is expected to help change people's view of reading which was boring to be fun. The design is a comfortable, varied, and fun reading space with complete facilities.
KONSEP EKOLOGI PADA RANCANGAN BALAI LATIHAN PENGOLAHAN SAMPAH DI BANJARBARU
Authors: Al Hauri Ahmad , Dahliani Dahliani 
Published: April 2024

The development of the city of Banjarbaru accompanied by an increase in population and community activities resulting. An increase in the amount of garbage produced. The ideal waste processing and sorting needs and active role from the community is still not running optimally, if these conditions are left the amount of waste that can actually be processed more go more to a landfill or waste damaging the environment. The design of the waste management training center uses the ecological concept with the uses of recycled material or reuse material derived from waste or second thing. Ecological concepts are applied by interactive methods that include design elements namely the wall, floor, plafond, interior, and the composition of the mass and landscape. That concept and method is a solution to create a design that can communicate the importance of community care for the environment and waste process.
Life Course Epidemiology of Hip Osteoarthritis in Japan
Authors: Sato Taishi , Yamate Satoshi , Utsunomiya Takeshi , Inaba Yutaka , Ike Hiroyuki , Kinoshita Koichi , Doi Kenichiro , Kawano Tsutomu , Shiomoto Kyohei , Hara Toshihiko , Sonoda Kazuhiko , Kaneuji Ayumi , Takahashi Eiji , Shimizu Tomohiro , Takahashi Daisuke , Kohno Yusuke , Kabata Tamon , Inoue Daisuke , Matsuda Shuichi , Goto Koji , Mawatari Taro , Baba Shoji , Takagi Michiaki , Ito Juji , Nakashima Yasuharu ,   the Japanese Hip OA Consortium
Published: April 2024

Background:
The incidence of developmental dysplasia of the hip (DDH) in Japanese newborns has reduced drastically following a primary prevention campaign initiated around 1972 to 1973; this perinatal education campaign promoted maintaining the hips of newborns in the naturally flexed-leg position. The purpose of the present study was to describe the life course epidemiology of hip osteoarthritis (OA) in adolescent and adult patients and to assess its association with exposure to the primary prevention campaign for DDH.

Methods:
We included new patients with hip OA diagnosed from January 1, 2022, to December 31, 2022, at 12 core hospitals (8 special-function hospitals and 4 regional medical care support hospitals). The trend in the percentage of hips with a history of DDH treatment in childhood was estimated with use of a centered moving average using the birth year of the patient. We compared the prevalence of severe subluxation (Crowe type II, III, or IV) between patients with secondary hip OA due to hip dysplasia who were born in or before 1972 and those who were born in or after 1973.

Results:
Overall, 1,095 patients (1,381 hips) were included. The mean age at the time of the survey was 63.5 years (range, 15 to 95 years). A total of 795 patients (1,019 hips; 73.8% of hips) were diagnosed with secondary OA due to hip dysplasia. Approximately 13% to 15% of hips among patients born from 1963 to 1972 had a history of DDH treatment in childhood; however, the percentage decreased among patients born in or after 1973. The prevalence of severe subluxation (Crowe type II, III, or IV) among patients born in or after 1973 was 2.4%, which was significantly less than that among patients born in or before 1972 (11.1%; odds ratio, 0.20; p < 0.001).

Conclusions:
As of 2022, secondary hip OA due to hip dysplasia is still responsible for most new cases of adolescent and adult hip OA seen in core hospitals in Japan. However, the perinatal education campaign initiated 50 years ago, which utilized a population approach and advocated for maintaining the hips of newborns in the naturally flexed-leg position, may have improved the environmental factors of DDH, as indicated by the apparently reduced need for treatment of DDH in childhood and the associated severe subluxation. This may result in a reduced need for challenging hip surgery later in life.

Level of Evidence:
Prognostic Level III. See Instructions for Authors for a complete description of levels of evidence.
Quantitative analysis of changing hazard exposure due to community growth in the Arequipa Region of Peru
Authors: Eberle Brook , Santi Paul , Meza Pablo 
Published: April 2024

Abstract

The Arequipa Region in Southern Peru is vulnerable to a unique set of geologic hazards which are a function of geology, climate, tectonic setting and the conditions of population settlement and local industries. The presence and expansion of mining in the region has the potential to directly affect geologic hazards by ground disruption and indirectly affect hazards by population increase and settlement in dangerous areas. We developed a set of geologic hazard maps for 12 communities in the region and quantified changes to hazard exposure based on community expansion patterns over time periods ranging from five to 17 years. Mapped hazards include debris flow, rockfall, flood, landslide, and earthquake liquefaction. Community expansion was measured from analysis of aerial imagery where developed areas are outlined at the beginning and end of the analyzed time interval. For the twelve communities evaluated, the percent of the developed area of each community exposed to hazards remained near constant, even with growth. Small changes were noted for specific hazards: rockfall was the most common hazard to have an increase in exposure, flood and liquefaction were the most likely to have decrease in exposure, while landslides (rotational or translational soil movements) and debris flows were the most likely to have no change. The percent of developed area exposed to high and medium levels of hazards in a community tended to decrease as development expanded over time, while area exposed to low levels of hazards increased. When analyzed by community characteristics, certain characteristics were associated with higher probability of larger changes in percent area exposed to hazards: river communities as opposed to coastal or mountain communities, small communities (< 0.5 km2 area), and communities located within 1.5 km of mining areas. Communities with extreme growth rates (more than 25% area increase per year) did not show different hazard exposure than communities with slower growth rates. The interaction between community growth and geologic hazards is an important area of future research.
Study of the mechanism pathway of sulfasalazine degradation on a novel quadripartite visible-light-driven photocatalyst
Authors: Omrani Narges , Nezamzadeh-Ejhieh Alireza 
Published: April 2024

Abstract

A novel coupled Cu2O-CdS-BiVO4-WO3 quadripartite nanoscale catalyst was prepared and characterized by XRD, SEM-DX, x-ray mapping, and DRS techniques. Its pHpzc was also determined to be about 9. The photodegradation experiments were designed via RSM. The optimal run in the photodegradation of sulfasalazine (SSZ) included the CSSZ: 7 mg/L, pH 6.25, 30 min irradiation time, 0.45 g/L of the catalyst dose, by a catalyst with a Cu2O-CdS-BiVO4-WO3 mole ratio 3:1:1:1 under visible light illumination. The effects of the scavenging agents were also studied, and the results confirmed the critical role of superoxide in SFSZ photodegradation and the hydroxyl radicals. The photodegradation pathway obeyed the direct Z-scheme mechanism, which involved three successive binary Z-scheme components involving WO3-BiVO4, BiVO4-CdS, and CdS-Cu2O, which accumulates the photoinduced electrons in the CB-Cu2O and the holes in the VB-WO3, the more powerful reducing and oxidizing centers, respectively.
TNF-alpha Inhibitors in Organ Transplant Recipients: A Retrospective Cohort Study
Authors: Madden Christopher , Thompson Katherine G. , Smith Isabelle T , Ike Jacqueline , Halle Briana R , Ahlers Carolyn , Mosley Dominique , Grossarth Sarah , Bibee Kristin , Wheless Lee 
Published: April 2024

Abstract

Tumor necrosis factor-alpha inhibitors (TNFi) can be an effective treatment for organ transplant recipients (OTR) with various diseases but can increase the risk of infection and drug interactions.1 There is also a potential for acute graft rejection while on TNFi with an unclear causal relationship. Two patients experienced acute graft rejection out of sixteen in a retrospective study of kidney transplant patients on TNFi, but the rejections were deemed unlikely to be related to biologic use.4 The purpose of this larger, multicenter study was to evaluate the safety of TNFi use in OTR by assessing rates of complications in patients treated with TNFi post-transplant.
Photoelectrochemical Ni-Catalyzed Cross-Coupling of Aryl Bromides with Amine at Ultra-Low Potential
Authors: Tang Zhiyong , Wang Jinghao , Li Siyang , Yang Caoyu , Gao Huiwen , Zuo Lulu , Guo Zhiyu , Yang Pengqi , Jiang Yuheng , Li Jian , Wu Li-Zhu 
Published: April 2024

Abstract

Photoelectrochemical (PEC) cell is an ideal platform for organic transformation because of its green benefits and minimal energy consumption. As an emerging methodology, the reaction types of photoelecrocatalytic organic synthesis (PECOS) are limited to simple oxidation and C–H activation at current stage. Metal catalysis with superiority in construction of C(sp2)–N bonds has not been touched yet in PECOS. We introduce here a PEC method that successfully engages Ni catalysis for the mild production of aniline derivatives. Experimental and computational investigations elucidate that the addition of photoanode-generated amine radical to Ni catalyst avoids the sluggish nucleophilic attack, enabling the reaction to proceed at an ultra-low potential (–0.4 V vs. Ag/AgNO3) and preventing the overoxidation of products in conventional electrochemical synthesis. This synergistic catalysis strategy exhibits good functional group tolerance and wide substrate scope on both aryl halides and amines, by which some important natural products and pharmaceutical chemicals have been successfully modified.