bluuebunny/crossref_metadata_2025_split huggingface dataset:
Exfoliate vaginal cytology and plasma concentrations of progesterone, luteinising hormone and oestradiol‐17sZ during oestrus in the bitch
Authors: Mestre J. , Wanke M. , Sucheyre S. 
Published: April 2008

ABSTRACTOestrus was characterised in nine German shepherd bitches by measuring plasma levels of luteinising hormone (LH), progesterone (P) and oestradiol‐17ß (O). Hormone concentration data were compared with the eosinophilic index (EI) obtained from exfoliate vaginal cytology. Maximal values of O and LH occurred before the maximal EI value. The EI peak followed the O peak, with a two day delay. LH increased during the first 24 hours after the maximum 0 value, and P levels were then slightly higher than basal.
Plasma concentration of some vitamins in greyhounds
Authors: Snow D. H. , Frigg M. 
Published: April 2008

ABSTRACTPlasma concentrations of ascorbic acid, (3‐carotene, retinol and a‐tocopheral were determined in four groups of racing greyhounds. Plasma biotin was measured in two groups. Mean concentrations were 5‐3 mg/litre ascorbic acid, 877|xg/litre retinol, 10‐4 mg/litre a‐tocopherol and 451 ng/litre biotin. In all dogs (3‐carotene was below the level of detection, ie, 20 μg/litre. Differences in plasma vitamin concentrations between groups were found.
Inherited erythrocyte Syruvate kinase eficiency in the West Highland white terrier
Authors: Chapman B. L. , Giger U. 
Published: April 2008

ABSTRACTAn eight‐month‐old male West Highland white terrier (WHWT) presented with mild exercise intolerance and splenomegaly caused by a severe and highly regenerative haemolytic anaemia that persisted until the dog died at two years of age. There was marked erythroid hyperplasia in the bone marrow and progressive osteosclerosis. Erythrocyte pyruvate kinase (PK) deficiency was confirmed by demonstrating a block in glycolysis at the PK step, abnormal erythrocyte PK kinetics, absence of R‐type PK isoenzyme, and the presence of M2‐type PK not normally expressed in erythrocytes. From the study of family members it is concluded that erythrocyte PK deficiency in the WHWT is inherited as an autosomal recessive trait. Heterozygotes have about half‐normal erythrocyte PK activity, do not express the M2‐type PK isoenzyme and are asymptomatic. This disease closely resembles erythrocyte PK deficiency in the basenji breed and should be considered as a differential diagnosis in young dogs with severe haemolytic anaemia.
Sagittal pubic osteotomy in the investigation and treatment of intrapelvic neoplasia in the dog
Authors: Davies J. V. , Read H. M. 
Published: April 2008

ABSTRACTSagittal pubic osteotomy was used as the surgical approach in 24 cases of intrapelvic neoplasia in the dog. Thirteen cases involved the urethra, seven cases the colorectum, one case the prostate and three cases the iliac periosteum. Surgical excision was performed in 10 cases of urethral neoplasia, four cases of rectal neoplasia, two cases of periosteal fibrosarcoma and one case of chondrosarcoma. The remaining cases were assessed as inoperable due to the extent of disease and euthanasia was carried out. Access to intrapelvic structures via a caudal midline laparotomy, perineal or dorsal routes or via an episiotomy is severely limited. The structures within the pelvic canal most likely to require surgical attention are the urethra, rectum and prostate. Procedures which require wide excision, accurate anastomotic techniques or relocation of intrapelvic organs necessitate an approach that allows generous exposure. A simple method of pubic osteotomy has been employed which has allowed resection of intrapelvic neoplasms.
Relapse infection after chemotherapy in dogs experimentally infected with Trypanosoma brucei brucei
Authors: Chukwu C. C. , Anene B. M. , Onuekwusi K. O. , Anika S. M. 
Published: April 2008

ABSTRACTStudies on relapsing Trypanosoma brucei brucei infections in dogs after Berenil treatment revealed that the first relapse occurred 13 to 64 days after chemotherapy and 36 to 79 days after inoculation. A second relapse infection was observed in two dogs 43 and 60 days after a second Berenil treatment. During the aparasitaemic period following chemotherapy in four dogs, successful transmission (as evidenced by subsequent parasitaemia) following the intraperitoneal inoculation of homogenate of brain from two of the dogs into recipient rats was obtained. Transmission with blood collected just before the animals were sacrificed was, however, negative. Hornogenates of other organs (liver, spleen, eyes, testes, kidneys, heart and lymph node) were also non‐infective. One dog inoculated with relapsed trypanosomes and treated with Berenil soon after showing parasitaemia was completely cured of the infection. It was considered that the brain is the source of relapse in T b brucei infection after Berenil therapy and that the relapse was not due to drug resistance.
Luxation of the radial carpal bone in four dogs
Authors: Miller A. , Carmichael S. , Anderson T. J. , Brown I. 
Published: April 2008

ABSTRACTFour cases of radial carpal bone luxation in dogs seen at Glasgow University Veterinary School in a period of six years are described. Three were border collie types. Two of these were working sheepdogs and the third was an agility triallist. The fourth was a rough collie. All were adult, two were male and two were female. Three cases were of short duration and were managed by open reduction of the luxation and surgical stabilisation of the radial carpal bone. The other was of longer duration and was treated by pancarpal arthrodesis. In all cases the carpus was supported externally for one to two months following surgery. At the time of writing, the progress of only the three working dogs was known. Despite the presence of osteoarthritic changes in the carpi of these dogs, they all became sound and returned to work. A mechanism for the injury based upon the results of cadaver studies is proposed.
Feline cowpox virus infection
Authors: Bennett M. , Gaskell C. J. , Baxbyt D. , Gaskell R. M. , Kelly D. F. , Naidoot J. 
Published: April 2008

ABSTRACTThe domestic cat is now the most commonly recognised host of cowpox virus in Great Britain and several recent cases of human cowpox have been traced to contact with infected cats. This review brings together some of the recent developments in our understanding of the natural history of cowpox virus and cowpox in cats.
Ultrasonographic measurement of normal renal parameters
Authors: Barr F. J. , Holt P. E. , Gibbs C. 
Published: April 2008

ABSTRACTBoth kidneys were imaged ultrasono‐graphically in each of 100 normal adult dogs. Small but significant differences were found in the dimensions of the left and right kidneys and in renal dimensions of male and female dogs of similar bodyweight. There was a statistically significant correlation between renal length and bodyweight (r = 0–84, P<0–001). The relationship between renal length and bodyweight was linear except at very low or very high bodyweights. There was also a statistically significant correlation between renal volume and bodyweight (r = 0–91, P<0–001), and the relationship remained linear even at extremes of bodyweight. Graphs could therefore be constructed for renal lengthy bodyweight and renal volume/bodyweight with 95 per cent confidence limits.
Severe whipworm infection in the dog
Authors: Malik R. , Hunt G. B. , Hinchliffe J. M. , Church D. B. 
Published: April 2008

ABSTRACTThree dogs with trichuriosis were presented because of depression, anorexia and severe dehydration following a period of chronic diarrhoea, Systemic signs attributable to hypovolaemia and acid‐base and electrolyte disturbances resolved following intravenous fluid therapy, although diarrhoea persisted until appropriate anthelmintics were administered. Whipworm infection may sometimes give rise to a life‐threatening dehydration syndrome associated with hyponatremia, metabolic acidosis and hyperkalemia.
Hiatal hernia in a shar‐pei
Authors: Williams J. M. 
Published: April 2008

ABSTRACTA combined axial and paraoesophageal hiatal hernia complicated by splenic involvement was diagnosed in a two‐year‐old Chinese shar‐pei. A circumcostal gastropexy was performed following reduction of the hernia and fundoplication of the cardia The dog recovered well and is asymptomatic six months postoperatively. The literature concerning hiatal hernia in the dog is reviewed and the various surgical techniques described for its management are discussed.
Studies on canine pregnancy using B‐mode ultrasound: Development of the conceptus and determination of gestational age
Authors: England G.C.W. , Allen W. Edward , Porter D. J. 
Published: April 2008

ABSTRACTDevelopment of the conceptus was characterised using B‐mode ultrasound in a standard size of dog (labrador retrievers, golden retrievers and their crosses; weight range 22 to 30 kg). Growth curves were established for various measurements of the conceptuses. Regression equations allowed the prediction of the expected time of parturition. Multiple regression analysis of two measurements (biparietal diameter and trunk diameter) resulted in an increase in the confidence of prediction.
Application of vaginal cytology and plasma Srogesterone eterminations to the management of reproduction in the bitch
Authors: Wright P. J. 
Published: April 2008

ABSTRACTThe use of vaginal cytology and plasma progesterone determinations in the management of 11 bitches presented to our small animal fertility clinic are described. Nine bitches were mated or artificially inseminated and seven became pregnant. Reproductive patterns detected included failure of ovulation, prolonged pro‐oestrus with late ovulation, short pro‐oestrus/oestrus with early ovulation, short pro‐oestrus/oestrus with late ovulation and normal pro‐oestrus/oestrus with late ovulation.
Bone haemangio‐sarcoma in a young Belgian malinois
Authors: Jennings P. B. , Andersen G. L. , Mathey W. S. , Okerberg C. V. 
Published: April 2008

ABSTRACTBone haemangiosarcoma in a young Belgian malinois initially presented as an abscess involving the Tight 10th rib. The dog responded promptly to abscess drainage and antibiotics. Anaemia and thrombocytopenia began one week later and ultrasonography revealed splenic and liver lesions. Exploratory surgery identified tumour masses in the spleen, liver, lung and rib. Histopathological diagnosis was hemangiosarcoma, possibly of bone origin.
A serological and bacteriological survey of leptospiral infection in dogs in Edinburgh and Glasgow
Authors: van den Broek A. H. M. , Thrusfield M. V. , Dobbiet G. R. , Ellisi W. A. 
Published: April 2008

ABSTRACTSera collected from 511 unvaccinated urban dogs were examined for antibodies to serovars of Leptospira interrogans representing nine serogroups found in the United Kingdom. The point estimates of the seroprevalence of leptospiral titres in Edinburgh and Glasgow at a minimum serum dilution of 1:10 were 23‐5 per cent and 27‐5 per cent, respectively, and, in Glasgow, the seroprevalence was significantly higher in males than females, for both crude and age‐adjusted values. Serovar canicola was the dominant strain identified, followed by serovars icterohaemorrhagiae, bratislava and ballum. Antibodies against serovars javanica and hardjo also were detected. Urine samples were collected from 84 of the male blood‐sampled dogs, and cultured. Serovars canicola and bratislava were isolated from three and four samples, respectively.
Prevalence of antibodies to four major canine viral diseases in dogs in a Liverpool hospital population
Authors: Tennant B. J. , Gaskell R. M. , Jones R. C. , Gaskell C. J. 
Published: April 2008

AbstractTo determine the prevalence of antibodies to four major canine viruses, serum samples were obtained from 190 dogs presented to the Small Animal Hospital at the University of Liverpool. Antibodies to canine coronavirus (CCV), canine distemper virus (CDV), canine parvovirus (CPV) and rotavirus (RV) were assayed using serum neutralisation (CCV and CDV), haemagglutina‐tion inhibition (CPV) and indirect fluorescent antibody (RV) techniques. Overall 54 per cent of dogs were seropositive to CCV, 84 per cent to CDV, 70 per cent to CPV and 86 per cent to RV, The antibody titres obtained were analysed with respect to a number of different parameters including: age, sex, breed, vaccination status, exercise regime, diet, Liverpool district in which the dog resided and the presence of diarrhoea, The prevalence and titres of antibodies to CCV, CDV and RV appeared to be influenced by age, CDV by vaccination status, and CCV by the presence of diarrhoea; no other influencing parameters were found.
A comparison of endotracheal and intravenous routes for atropine administration in anaesthetised dogs
Authors: Bor A. , Jones R. S. , Richards D. L. S. 
Published: April 2008

AbstractThe endotracheal route for atropine administration was compared with the intravenous route in 50 anaesthetised dogs. The response to drug administration was recorded as the change in heart rate from a steady pretreatment value. An indication was found of a positive relationship between the dose and the response to atropine given endotracheally. The increase in heart rate following atropine administration was similar, in terms of magnitude and speed of onset, when given by the endotracheal route at 0–06 mg/kg, as compared with that obtained by the intravenous administration of atropine at 0–04 mg/kg (P<0–05).
Acquired immune‐mediated myasthenia gravis in a cat associated with a cystic thymus
Authors: O'Dair H. A. , Holt P. E. , Pearson G. R. , Gruffydd‐Jones T. J. 
Published: April 2008

AbstractAcquired myasthenia gravis was diagnosed in a five‐year‐old domestic shorthair, neutered, female cat with generalised muscle weakness, tremors, dysphagia and alterations in voice. Radiographs indicated the presence of a mass in the anterior thorax. A response to edrophonium chloride, and raised levels of anti‐acetylcholine receptor antibodies in the serum, confirmed the diagnosis and indicated an immune‐mediated aetiology. Clinical remission occurred following thymectomy and the use of immunosuppressive corticosteroids. This is the first fully‐documented case of acquired feline myasthenia gravis associated with the presence of a thymic abnormality in the United Kingdom. The clinical features, laboratory findings and response to treatment are compared with those reported previously in cats and other species.
Breed, sex and age distribution in dogs with chronic liver disease: a demographic study
Authors: Andersson M. , Sevelius E. 
Published: April 2008

ABSTRACTBreed, sex and age distribution were studied in dogs with histopathologically diagnosed chronic (active or progressive) hepatitis and liver cirrhosis in Sweden. The study was based on clinical and histopathological records obtained during three years from a histopathological laboratory and during six years from an animal hospital. Some breeds were significantly (P<0–001) over‐represented: American and English cocker spaniels, labrador retrievers and West Highland white terriers. In both spaniel breeds the males were most frequent whereas in the labrador retriever, the females were over represented. In the West Highland white terrier there was no sex difference. The average age at presentation was approximately five years in spaniels and West Highland white terriers and seven years in labrador retrievers. The high incidence of chronic liver disease and liver cirrhosis in certain breeds indicate that hereditary factors may be of importance in the development of chronic hepatitis and liver cirrhosis.
Dental radiology: ageing changes in permanent teeth of beagle dogs
Authors: Morgan J. P. , Miyabayashi T. 
Published: April 2008

ABSTRACTRadiographic interpretation of dental or periodontal disease is dependent in part on an understanding of ageing changes, A progressively ageing colony of healthy beagle dogs (120 to 3759 days) was studied by use of high‐detail radiographs made following the death of the dog. Morphological features whose radiographic appearance was found to be especially age‐dependent were: root canal size, both vertical and horizontal alveolar bone resorption, visualisation of the lamina dura dentis, and detection of hypercementosis. Understanding of these ageing changes is necessary to avoid over‐diagnosis of disease.
Abnormal ocular pigment deposition associated with glaucoma in the cairn terrier
Authors: Petersen‐Jones S. M. 
Published: April 2008

ABSTRACTA condition involving ocular pigment deposition was diagnosed in six cairn terriers. In each, there was pigment deposition in a number of ocular sites, including the episclera, and ventral anterior chamber and drainage angle. Four of the dogs (aged 10 years or older) had developed a chronic glaucoma, which was presumed to be secondary to pigment deposition in the drainage angle. The other two dogs (six‐year‐old litter mates) had not developed glaucoma but there were pigmented particles in the aqueous and abnormal pigment deposition within the episclera and drainage angle. They also had a raised circumferential band protruding from the periphery of the iris into the anterior chamber.
Metastatic pilomatrixoma presenting as paraplegia in a dog
Authors: Ham L. Van. , van Bree H. , Maenhout T. , Tshamala M. , Broekaertt D. , Hoorens J. , Mattheeuws D. 
Published: April 2008

ABSTRACTA three‐year‐old giant poodle with a subacute paraplegia had a metastasic pilomatrixoma in vertebrae Tl, LI and L4, ulna, humerus, tibia and lymph nodes. Pilomatrixoma is generally considered as a benign tumour of the skin. This is the first report on pilomatrixoma metastasing to bone and causing neurological signs.
Pyothorax associated with a Mycoplasma species in a kitten
Authors: Malik R. , Love D. N. , Hunt G. B. , Canfield P. J. , Taylor V. 
Published: April 2008

ABSTRACTA 12‐week‐old kitten with congenital mitral valve dysplasia was shown by ante mortem and post mortem examination to have pneumonia and purulent pleurisy. A Mycoplasma species was isolated from a sample of pleural fluid collected at necropsy. Mycoplasmosis should be considered in the differential diagnosis of pyothorax in cats.
Vecuronium infusion in the dog
Authors: Jones R. S. , Young L. E. 
Published: April 2008

ABSTRACTThe non‐depolarising muscle relaxant vecuronium bromide was administered to 20 dogs undergoing a variety of surgical procedures under general anaesthesia. An initial dose of 0–1 mg/kg was administered and followed by an infusion of 0–1 mg/kg/hour. Reversal of the neuromuscular block was carried out with neostigmine and atropine.
Pharmacokinetics of aditoprim in dogs after intravenous and oral administration: a preliminary study
Authors: Sutter H.‐M. , Ludwig B. , Bremer K. D. , Jordan J.‐C. , Rehm W. F. , Wanner M. 
Published: April 2008

ABSTRACTThe pharmacokinetics of aditoprim (2,4‐diam‐ino‐5‐[4‐[dimethylamino]‐3,5‐dimethoxybenzyl] pyrimidine), a dihydrofolate reductase inhibitor, were studied in three eight to 17‐month‐old beagle dogs. The drug was alternately injected intravenously and administered orally as a tablet in two separate experiments. The doses ranged from 4–27 to 7–25 mg/kg bodyweight. The mean plasma clearance (CI) was 15‐3 ml/min/kg and the mean volume of distribution (Vss) 13‐1 litres/kg. The mean plasma elimination half‐life times after intravenous injection and oral administration were 11‐6 and 9‐6 hours, respectively. Aditoprim was readily (tmax= one to four hours) and completely absorbed from the intestinal tract (f = 89 per cent).
Prednisolone‐responsive neuropathy in a cat
Authors: Malik R. , France M. P. , Churcher R. , McDonald B. 
Published: April 2008

ABSTRACTChronic relapsing polyneuropathy was diagnosed in a 15‐month‐old cat with a 12‐week history of limb weakness. The clinical course was punctuated by spontaneous remissions and relapse. There were two striking physical findings, weak withdrawal reflexes and atrophy of the proximal and distal limb muscles. Electrophysiological findings typical of a demyelinating motor neuropathy were present, namely small, dispersed compound muscle action potentials, markedly slow motor conduction and denervation potentials that were more prominent dis‐tally. Muscle biopsies showed changes consistent with denervation and a paucity of myelinated axons in intramuscular nerve bundles. The neuropathy responded rapidly and completely to prednisolone administration, which was slowly tapered over several months.
Clinical features and heritability of osteochondrosis of the elbow in labrador retrievers
Authors: Studdert V. P. , Lavelle R. B. , Beilharz R. G. , Mason T. A. 
Published: April 2008

ABSTRACTThe occurrence of osteochondrosis in a breeding colony of labrador retrievers during an 11‐year period was investigated. Management practices and environmental factors were similar for all dogs. In 1247 progeny, elbow lameness was recorded in 259 dogs (21 per cent) and lesions of osteochondrosis on the coronoid process and, or, medial condyle of the humerus were confirmed in 189 dogs (15 per cent). None of 39 labrador crossbred dogs were affected. The incidence in progeny varied between different sires and dams and was associated with the severity of radiographic evidence of elbow arthritis in sires and dams with dams contributing significantly more than sires, suggesting a ‘maternal’ effect.
Hypercalcaemia in the dog: a study of 40 cases
Authors: Elliott J. , Dobson J. M. , Dunn J. K. , Herrtage M. E. , Jackson K. F. 
Published: April 2008

ABSTRACTForty dogs referred to the University Department of Clinical Veterinary Medicine, Cambridge for medical and oncological conditions between 1985 and 1990 were found to be hypercalcaemia In 18 cases the primary or underlying condition was diagnosed as lymphoproliferative disease with multicentric lymphoma occurring most commonly. Ten dogs were suffering from hypoadrenocorticism (Addison's disease) and two had adenocarcinomas of the apocrine glands of the anal sac. In three dogs a clinical diagnosis of renal dysplasia was made, this diagnosis being confirmed at post mortem examination in one dog. In the remaining cases hypercalcaemia was associated with a primary lung tumour, a thymoma, an osteosarcoma with widespread skeletal metastases, primary hyperparathyroidism due to a parathyroid adenoma, chronic panniculitis, iatrogenic hypoadrenocorticism following mito‐tane therapy (one case each] and, in a further case, no diagnosis was reached. The most common clinical signs were inappetence, polyuria/ polydipsia, weakness, vomiting, lethargy and depression. As a group, the dogs with lymphoproliferative disease had a significantly higher mean plasma calcium concentration (4‐3 ± 0–7 vs 3–5 ± 0–4 mmol/litre), a significantly lower mean plasma inorganic phosphate concentration (1–5 ± 0–5 vs 2–4 ± 09 mmol/litre) and were significantly older (5‐5 ± 2–4 vs 3‐3 + 1–8 years) than the dogs with hypoadrenocorticism.