bluuebunny/crossref_metadata_2025_split huggingface dataset:
Rapid Synthesis of 4‐Benzylidene and 4‐[Bis‐(4‐methoxyphenyl)‐methylene]‐2‐substituted Phenyl‐Benzopyrans as Potential Selective Estrogen Receptor Modulators (SERMs) Using McMurry Coupling Reaction.
Authors: Gupta Atul , Dwivedy Anila , Keshri Govind , Sharma Ramesh , Balapure Anil Kumar , Singh Man Mohan , Ray Suprabhat 
Published: February 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Synthesis of Benzo[g]isochromenes Through Photo‐Dehydro‐Diels—Alder Reaction.
Authors: Wessig Pablo , Mueller Gunnar , Herre Robert , Kuehn Andreas 
Published: February 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Synthesis of the 7‐Azaindole (1H‐Pyrrolo[2,3‐b]pyridine) Analogous to Cannabimimetic JHW 200.
Authors: Gluszok Sebastien , Goossens Laurence , Depreux Patrick , Barbry Didier , Henichart Jean‐Pierre 
Published: February 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Coupling of β‐Cyanocarbene‐chromium Complexes with 2‐Alkynylbenzoyl Derivatives: A [5 + 5]‐Cycloaddition Approach to Phenanthridines.
Authors: Ghorai Binay K. , Duan Shaofeng , Jiang Delu , Herndorn James W. 
Published: February 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Synthesis of Purines Bearing Functionalized C‐Substituents by the Conjugate Addition of Nucleophiles to 6‐Vinylpurines and 6‐Ethynylpurines.
Authors: Kuchar Martin , Pohl Radek , Votruba Ivan , Hocek Michal 
Published: February 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Palladium‐Catalyzed Cross‐Coupling Reactions of Diazine N‐Oxides with Aryl Chlorides, Bromides, and Iodides.
Authors: Leclerc Jean‐Philippe , Fagnou Keith 
Published: February 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Entrapment of a Dirhodium Tetracarboxylate Unit Inside the Aromatic Bowl of a Calix[4]arene: Unique Catalysts for C—H Amination.
Authors: Brodsky Benjamin H. , Du Bois J. 
Published: February 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Cyclohexanedione Bisaminals as Intermediates for Cyclen, Homocyclen, and Cyclam Synthesis.
Authors: Prokhorov Anton , Le Bris Nathalie , Bernard Helene , Claudon Geraldine , Handel Henri 
Published: February 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Synthesis of 1,2,4‐Trioxepanes via Application of Thiol‐Olefin Co‐Oxygenation Methodology.
Authors: Amewu Richard , Stachulski Andrew V. , Berry Neil G. , Ward Stephen A. , Davies Jill , Labat Gael , Rossignol Jean‐Francois , O'Neill Paul M. 
Published: February 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Bioactive Diterpenes from the Mangrove Avicennia officinalis Linn.
Authors: Subrahmanyam C. , Kumar S. Ratna , Reddy G. Damodar 
Published: February 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Total Synthesis of the Chlorinated Marine Natural Product Dysamide B.
Authors: Durow Amanda C. , Long G. Cliona , O'Connell Susan J. , Willis Christine L. 
Published: February 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Generation of an S‐Peptide via an N—S Acyl Shift Reaction in a TFA Solution.
Authors: Nakamura Ken'ichiroh , Sumida Megumi , Kawakami Toru , Vorherr Thomas , Aimoto Saburo 
Published: February 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Chiral Stability of Phosphonium‐Type Amino Acid Ionic Liquids.
Authors: Fukumoto Kenta , Kohno Yuki , Ohno Hiroyuki 
Published: February 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
A Sugar‐Quinoline Fluorescent Chemosensor for Selective Detection of Hg2+ Ion in Natural Water.
Authors: Ou Shengju , Lin Zhihua , Duan Chunying , Zhang Haitao , Bai Zhiping 
Published: February 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Concise Synthesis of the (.+‐.)‐Nb‐Desmethyl‐meso‐chimonanthine.
Authors: Menozzi Candice , Dalko Peter I. , Cossy Janine 
Published: February 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Silver‐Catalyzed Asymmetric Synthesis of 2,3‐Dihydrobenzofurans: A New Chiral Synthesis of Pterocarpans.
Authors: Jimenez‐Gonzalez Leticia , Garcia‐Munoz Sergio , Alvarez‐Corral Miriam , Munoz‐Dorado Manuel , Rodriguez‐Garcia Ignacio 
Published: February 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Isokibdelones: Novel Heterocyclic Polyketides from a Kibdelosporangium sp.
Authors: Ratnayake Ranjala , Lacey Ernest , Tennant Shaun , Gill Jennifer H. , Capon Robert J. 
Published: February 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Total Synthesis of (+)‐cis‐Sylvaticin: Double Oxidative Cyclization Reactions Catalyzed by Osmium.
Authors: Donohoe Timothy J. , Harris Robert M. , Burrows Jeremy , Parker Jeremy 
Published: February 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
1‐Aryltetralin Privileged Structure‐Based Libraries: Parallel Synthesis of N‐Aryl and N‐Biaryl γ‐Lactam Lignans.
Authors: Dorbec Matthieu , Florent Jean‐Claude , Monneret Claude , Rager Marie‐Noelle , Bertounesque Emmanuel 
Published: February 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Synthesis of the Mycolactone Core by Ring‐Closing Metathesis.
Authors: Alexander Matthew D. , Fontaine Shaun D. , La Clair James J. , DiPasquale Antonio G. , Rheingold Arnold L. , Burkart Michael D. 
Published: February 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
The Novel Antimalarial Compound Dioncophylline C Forms a Complex with Heme in Solution
Authors: Schwedhelm Kai F. , Horstmann Martin , Faber Johan H. , Reichert Yana , Bringmann Gerhard , Faber Cornelius 
Published: February 2007

AbstractA structural model of the complex formed between the novel antimalarial compound dioncophylline C (DioC) and its presumed target ferriprotoporphyrin IX heme (FPIX) is presented. The complex structure was calculated with molecular dynamics (MD) simulations using intermolecular distance restraints between DioC and the iron center in FPIX, determined from NMR paramagnetic relaxation. Besides the spin state of the iron and longitudinal relaxation rates of hydrogen nuclei in DioC, the effective correlation time of paramagnetic relaxation was determined from NMR measurements at three different magnetic field strengths. The derived structural model shows high similarity to complexes formed by FPIX and antimalarials of the quinoline family (chloroquine, quinine, quinidine, and amodiaquine). The conformation of DioC is sterically stabilized by a water molecule coordinated to iron in FPIX. This structural feature may provide an important hint at possibilities for a further optimization of novel naphthylisoquinoline alkaloid (NIQ) antimalarial drugs.
Modified lipoproteins as contrast agents for imaging of atherosclerosis
Authors: Frias Juan C. , Lipinski Michael J. , Lipinski Shawn E. , Albelda M. Teresa 
Published: February 2007

AbstractThe ability to detect and characterize atherosclerosis with targeted contrast agents may enable initiation of therapy for atherosclerotic lesions prior to becoming symptomatic. Since lipoproteins such as high‐density lipoprotein (HDL) and low‐density lipoprotein (LDL) play a critical role in the regulation of plaque biology through the transport of lipids into and out of atherosclerotic lesions, modifying HDL and LDL with radioisotopes for nuclear imaging, chelates for magnetic resonance imaging (MRI) or other possible contrast agents for computed tomography imaging techniques may aid in the detection and characterization of atherosclerosis. This review focuses on the literature employing lipoproteins as contrast agents for imaging atherosclerosis and the feasibility of this approach. Copyright © 2007 John Wiley & Sons, Ltd.
Channel modeling of nondirected wireless infrared indoor diffuse link
Authors: Hayasaka Naoki , Ito Takeshi 
Published: February 2007

AbstractThis paper discusses the modeling and broadband design of an indoor infrared wireless communication channel consisting of a nondirected diffusion system. The property of the nondirected diffuse link is analyzed by the ray tracing technique and the modified Monte Carlo method. The physical parameters are directly related to the impulse response of the link and are modeled by a gamma probability density function. The impulse response model and a simulation indicate that it is effective for the broadband link to narrow the radiation angle of the optical source and to expand the receiver field of view to match the ceiling area of the room. © 2007 Wiley Periodicals, Inc. Electron Comm Jpn Pt 1, 90(6): 9–19, 2007; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/ecja.20352
Performance evaluation of 6000‐A‐class superconducting field windings for 600‐MW‐class superconducting generators
Authors: Maeda Susumu , Shimohata Kenji , Kodera Itsuo , Sano Hideaki , Izumi Akifumi 
Published: February 2007

AbstractSuperconducting generators have many advantages such as increasing generator efficiency and improving power system stability. In Japan, a national project has been conducted since 2000 which is aimed at the development of fundamental technologies required for high‐output‐density and large‐capacity superconducting generators. This paper describes the results of this project, focusing on 6000‐A‐class field winding development. Copyright © 2004 Wiley Periodicals, Inc.A superconducting generator with a high output density and a large capacity has inherent factors that decrease superconducting stability. These are: (1) increase in the magnetic field in the winding which is caused by the increase in winding current density and (2) difficulty in fabricating windings which increases as a conductor diameter becomes larger. To secure the stability, we adopted a higher‐copper‐content conductor and a design that increases winding fixing pressure, along with devising a winding method that accommodates larger conductor diameter. These improvements were applied to a partial model of a 600‐MW field winding. Test results of the model showed good stability, indicating that design and fabrication technique for a 6000‐A‐class superconducting field winding has been successfully evaluated. © 2007 Wiley Periodicals, Inc. Electr Eng Jpn, 159(2): 7– 18, 2007; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/eej.20332
Synthesis and Structural Characterisation of Copper(II) 15‐Metallacrown‐5 Complexes with PbII, HgII, AgI, NaI and YIII Central Metal Ions
Authors: Seda Sabry Hamed , Janczak Jan , Lisowski Jerzy 
Published: February 2007

AbstractThe new copper(II) 15‐metallacrown‐5 complexes with the central metal ions PbII, HgII, AgI, NaI and YIII, with the formula [MCu5L5]Xn {H2L is 2‐picolinehydroxamic acid or (S)‐phenylalaninehydroxamic acid and X– is NO3– or Cl–}, have been synthesised and characterised by NMR and UV/Vis spectroscopy, electrospray mass spectrometry and elemental analysis. The PbII‐ and HgII 15‐metallacrown‐5 complexes were obtained in the crystalline form as pyridine adducts [PbCu5(picha)5(py)6](NO3)2·3(py) and [HgCu5(picha)5(py)7](NO3)2·2(py) and their X‐ray crystal structures were determined. In both complexes, each peripheral CuII ion of the metallacrown is coordinated by one pyridine molecule bonded in the axial position. In the case of the PbII derivative, one additional axial pyridine molecule is bound to the central metal ion, while in the case of the HgII derivative, two axial pyridine ligands are bound to the central HgII ion. The relative stability of the copper(II) 15‐metallacrown‐5 complexes with various central metal ions was determined on the basis of competition reactions. The relative preference of the 15‐metallacrown‐5 system for the central metal ion follows the series NaI, AgI < lanthanide(III), HgII < PbII.(© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2007)
Synthesis and Structural Characterisation of Diorganotin(IV) and Diphenyllead(IV) Complexes of Pyrimidine‐2‐thionate Derivatives
Authors: Rodríguez Antonio , Sousa‐Pedrares Antonio , García‐Vázquez J. Arturo , Romero Jaime , Sousa Antonio , Russo Umberto 
Published: February 2007

AbstractThe reaction between the ligands 4‐(trifluoromethyl)pyrimidine‐2‐thione (4‐CF3pymSH) and 6‐methyl‐4‐(trifluoromethyl)pyrimidine‐2‐thione (6‐Me‐4‐CF3pymSH) and the corresponding diorganotin(IV) dichloride [R2SnCl2] (R = Me, tBu or Ph) or diphenyllead(IV) dichloride in the presence of triethylamine yields the diorganotin(IV) complexes [R2Sn(4‐CF3pymS)2] and [R2Sn(6‐Me‐4‐CF3pymS)2] or diorganolead(IV) complexes [Ph2Pb(4‐CF3pymS)2] and [Ph2Pb(6‐Me‐4‐CF3pymS)2], respectively. The compounds have been characterised by microanalysis, mass spectrometry and by IR and Mössbauer spectroscopy and, in the case of the compound that was sufficiently soluble, by 1H, 13C, 119Sn and 207Pb NMR spectroscopy. The compounds [Me2Sn(4‐CF3pymS)2] (1), [Ph2Sn(4‐CF3pymS)2] (2), [Ph2Sn(6‐Me‐4‐CF3pymS)2] (5), [tBu2Sn(6‐Me‐4‐CF3pymS)2] (6), [Ph2Pb(4‐CF3pymS)2] (7) and [Ph2Pb(6‐Me‐4‐CF3pymS)2] (8) have also been characterised by X‐ray diffraction. The X‐ray crystal structures show that the metal centre in all these complexes is in a distorted octahedral environment with bonds to two carbon atoms from the aryl or alkyl substituents and to sulfur and heterocyclic nitrogen atoms from the pyrimidine derivative, which acts a (κ2‐N,S) chelating ligand. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2007)
Method for selecting exposure levels for the Drosophila sex‐linked recessive lethal assay
Authors: Thompson E. D. , Reeder B. A. 
Published: February 2007

AbstractThe use of the Drosophila sex‐linked recessive lethal assay for detecting mutagenicity of chemicals is well established. When compounds are tested by feeding adult flies, the National Toxicology Program protocol specifies a 3‐day feeding regimen at an exposure level that produces about 30% mortality. Uptake of the test compound is monitored by feeding behavior, amount of excretion, or abdomen size (Woodruff et al: Environ Mutat 7:677–702, 1985). An alternate method for determining uptake is to add radiolabeled sucrose to the feeding solution and then to determine the amount of radioactivity in the flies (Gollapudi et al: Mutat Res 144:13–17, 1985). We have found that the addition of radiolabeled sucrose underestimates consumption for feeding exposures longer than 24 hr because sucrose is metabolized and as much as 30% of the label is excreted, presumably as 14CO2 or 3H2O. Here we describe a method for determining uptake of chemicals by adding 14C‐leucine to the feeding solution. The incorporation of 14C‐leucine is essentially linear over the 3‐day feeding period, which permits accurate estimates of food consumption. Use of this method demonstrates that lower exposure levels of a chemical that do not produce mortality actually results in higher consumption by the flies. The method is proposed as a prescreen to select the appropriate exposure level for the sex‐linked recessive lethal assay.
Effects of cigarette smoking and solvent exposure on sister chromatid exchange frequency in painters
Authors: Kelsey Karl T. , Wiencke John K. , Little Frederic F. , Baker Edward L. , Little John B. 
Published: February 2007

AbstractA cross‐sectional study of sister chromatid exchange frequency (SCE) in peripheral blood lymphocytes from 117 members of the International Brotherhood of Painters and Allied Tradesman was conducted in union locals in two major U.S. cities. Chronic solvent exposure intensity and duration were estimated from interviewer‐administered‐questionnaire data. SCE for all of the workers in the study were scored by one reader. A second reader determined the SCE frequency from a random sample of 30 workers. No significant difference in SCE frequency was associated with reader or time of reading. Age, coffee and alcohol intake and chronic solvent exposure (both intensity and duration, estimated over the working lifetime and over the year prior to study for each worker) did not significantly elevate SCE. The effect of smoking on SCE frequency, assessed by analysis of variance controlling for other possible confounding factors, showed that smoking increased SCE frequency (P < .0001). The SCE frequency in the smoking, solvent‐exposed (estimated as lifetime exposure) painters was 6.75 SCE/cell; in the non‐smoking, solvent‐exposed workers the SCE frequency was 5.73 SCE/cell; the controls had SCE levels of 6.84 SCE/cell (smokers) and 5.90 SCE/cell (non‐smokers), respectively. These observations are consistent with other work suggesting that chronic solvent exposure in the paint trade is not associated with an elevation in SCE in peripheral blood lymphocytes. However, further work is necessary to address adequately the question of the genotoxicity of acute solvent exposure in these workers.
Reactivity of catecholamines and related substances in the mouse lymphoma L5178Y cell assay for mutagens
Authors: McGregor Douglas B. , Riach Colin G. , Brown Alison , Edwards Ian , Reynolds Deborah , West Katrine , Willington Sarah 
Published: February 2007

AbstractUsing the L5178Y mouse lymphoma cell thymidine kinase locus and the Salmonella his locus assays, the mutagenic potentials of several catecholamines and related compounds were examined. No supplementary metabolic activation systems were used. In the mouse lymphoma assay, the dihydroxybenzenes catechol and hydroquinone had similar and appreciable mutagenic potentials, whereas resorcinol was less active. Derivatives of catechol, such as dopamine and epinephrine, were mutagenic, whereas the related monohydroxylated compounds tyramine and synephrine were inactive. The primary amine, arterenol, and the corresponding secondary amine, epinephrine, induced similar mutagenic responses. Carboxylation of the side chain of dopamine, giving L‐dopa, reduced the maximum mutagenic response. The introduction of charged groups directly on to the aromatic ring also reduced mutagenic activity, while an intervening methylene reversed this effect. Thus, 3,4‐dihydroxyhydrocinnamic acid was more active than 3,4‐dihydroxybenzoic acid. The compound active at the lowest doses was 4‐tert‐butyl catechol. The activities of these compounds are highly dependent upon substituent groups. Experiments with superoxide dismutase gave circumstantial evidence for some of the mutagenic activity being due to superoxide anion. Active oxygen species might be responsible for some of the observed effects, but this cannot be concluded from the superoxide dismutase experiments. Mutagenic responses in Salmonella were very low but were significant for L‐dopa in three strains and for epinephrine and arterenol in one strain. Limited DNA association studies of 14C‐dopamine suggest interactions in L5178Y and Salmonella cells and in mouse liver. The mutagenicity of dopamine in L5178Y is reduced by high serum concentrations during the exposure period, while the apparent association with DNA is unaffected.
Absence of cinoxacin‐induced DNA fragmentation and mutations in the rat granuloma pouch
Authors: Pino Albiana , Maura Annalisa , Grillo Patrizia 
Published: February 2007

AbstractThe mutagenic and DNA‐damaging activities of cinoxacin were evaluated in the rat granuloma pouch assay (GPA) in order to assess its genotoxic potential in vivo. High doses of this antimicrobial quinolone, either directly injected into the pouch or administered by gavage, did not induce mutation at the hgprt locus or DNA fragmentation in granuloma cells. Moreover, DNA damage was absent in the liver and kidney of rats given cinoxacin by the oral route.
Mutagenicity of urine from mice exposed orally to nitrite and various aminated antiparasitic drugs
Authors: Alba M. Arriaga , Aguirre J. Espinosa , Ramírez J. , Cortinas de Nava C. 
Published: February 2007

AbstractMutagenic N‐nitroso compound formation from the in vitro reaction of amebicides and anthelmintic drugs, which are pyrimidine derivatives or contain secondary aliphatic amines or heterocyclic nitrogens, has been previously described (Arriaga Alba et al.: Environmental and Molecular Mutagenesis 12:65–73, 1988). Under similar conditions, antiparasitic drugs containing halogenated derivatives of tertiary amines or quaternary ammonium salts do not form mutagenic nitrosated compounds. In the present study the mutagenic activity of mouse urine was determined after oral administration of sodium nitrite and the two above‐mentioned groups of drugs (pyrantel pamoate, chloroquine, piperazine anddehydroemetine/iodochlorhydroxyquin and bephenium hydroxynaphthoate, respectively). Results show that the simultaneous administration of piperazine or chloroquine with sodium nitrite produced urinary mutagens that appeared conjugated as glucuronides, whereas pyrantel pamoate and dehydroemetine in the presence of nitrite caused only slightly mutagenic urine. No mutagenic activity was detected in the urine of mice to which halogenated derivatives of tertiary amines (iodochlorhydroxyquin) or quaternary ammonium salts (bephenium hydroxynaphthoate) were administered together with nitrite.