bluuebunny/crossref_metadata_2025_split huggingface dataset:
IFITM3 inhibits severe fever with thrombocytopenia syndrome virus entry and interacts with viral Gc protein
Authors: Du Shouwen , Wang Yuhang , Wang Jiamin , Ma Yidan , Xu Wang , Shi Xiaoshuang , Li Letian , Hao Pengfei , Liu Quan , Liao Ming , Zhou Boping , Jin Ningyi , Wong Yin K. , Hu Lifen , Wang Jigang , Liu Wei , Li Chang 
Published: February 2024

AbstractSevere fever with thrombocytopenia syndrome (SFTS) is an emerging tick‐borne hemorrhagic fever disease with high fatality rate of 10%–20%. Vaccines or specific therapeutic measures remain lacking. Human interferon inducible transmembrane protein 3 (hIFITM3) is a broad‐spectrum antiviral factor targeting viral entry. However, the antiviral activity of hIFITM3 against SFTS virus (SFTSV) and the functional mechanism of IFITM3 remains unclear. Here we demonstrate that endogenous IFITM3 provides protection against SFTSV infection and participates in the anti‐SFTSV effect of type Ⅰ and Ⅲ interferons (IFNs). IFITM3 overexpression exhibits anti‐SFTSV function by blocking Gn/Gc‐mediated viral entry and fusion. Further studies showed that IFITM3 binds SFTSV Gc directly and its intramembrane domain (IMD) is responsible for this interaction and restriction of SFTSV entry. Mutation of two neighboring cysteines on IMD weakens IFITM3‐Gc interaction and attenuates the antiviral activity of IFITM3, suggesting that IFITM3‐Gc interaction may partly mediate the inhibition of SFTSV entry. Overall, our data demonstrate for the first time that hIFITM3 plays a critical role in the IFNs‐mediated anti‐SFTSV response, and uncover a novel mechanism of IFITM3 restriction of SFTSV infection, highlighting the potential of clinical intervention on SFTS disease.
Late Quaternary ostracode stratigraphy of Mono Lake (California, USA): evidence for benthic ecosystem sensitivity to climate change
Authors: Hodelka BAILEE N. , Mcglue MICHAEL M. , Palacios‐Fest MANUEL R. , Benfield ADAM J. , Ivory SARAH J. , Starratt SCOTT W. , Zimmerman SUSAN R. H. 
Published: February 2024

ABSTRACTThe response of aquatic ecosystems in the Sierra Nevada (California, USA) to late Quaternary hydroclimate changes remains mostly unknown. Mono Lake, a large endorheic lake just east of the Sierra Nevada, contains an expanded archive of laminated sediments that can be used to examine the response of benthos to environmental changes. Fossil ostracodes from a radiocarbon‐dated core were used to examine paleoecologic changes from ~16.6 to 4.3k cal a bp. Seven species were identified, with the co‐occurrence of Limnocythere ceriotuberosa and Limnocythere staplini indicating a large SO42−‐rich lake in the Pleistocene. The Younger Dryas was complex, with Fabaeformiscandona caudata reflecting a cold and deep lake ~13.0–12.2k cal a
bp, followed by an interval of extensive littoral habitat from ~12.2–11.6k cal a
bp. Ostracode diversity, valves g–1 and the ratio of adult:juvenile valves declined after ~10.7k cal a
bp due to regression, altered hydrochemistry and seasonal anoxia. Strong seasonality during the Early Holocene is suggested by the presence of reworked ostracodes and macrocharcoal, delivered to Mono Lake by erosion of ancient lake beds in the basin. A depauperate ostracode fauna in the Middle Holocene suggests a strong sensitivity to drought in this ecosystem, which has implications for biodiversity in the future.
Guanidinium‐Based Manganese(II) Bromide with High Glass‐Forming Ability for Thermoplastic Curved X‐ray Imaging
Authors: He Zi‐Lin , Wei Jun‐Hua , Luo Jian‐Bin , Zhang Zhi‐Zhong , Chen Jing‐Hua , Guo Xiu‐Xian , Kuang Dai‐Bin 
Published: February 2024

AbstractThe development of large‐area transparent organic‐inorganic hybrid metal halide (OIMH) scintillation screens is restricted by the anisotropic single‐crystal growth, numerous grain boundaries in polycrystalline wafers, and inhomogeneous dispersion in perovskite‐polymer composite films. The crystal‐glass phase transition of OIMH materials may provide a promising solution for the above significant challenges. Herein, a new class of transparent amorphous guanidinium‐based manganese bromide glasses, (DPG)2MnBr4 and (DOTG)2MnBr4 (DPG = 1,3‐diphenylguanidinium, DOTG = 1,3‐di‐o‐tolylguanidinium), are synthesized through a low‐temperature melt‐quenching process. The (DOTG)2MnBr4 shows impressive glass‐forming ability because of large viscosity (η) at the melting temperature (Tm) (η(Tm) = 3426 mPa·s) and small fragility index (m = 52.35), which can be a potential glass scintillator. The large‐area (e.g., 13 cm × 13 cm) transparent amorphous (DOTG)2MnBr4 glass scintillator shows high light transmittance of > 80%, a low detection limit of 237.3 nGy s−1 and high X‐ray imaging spatial resolution of 12 lp mm−1. Interestingly, the glass transition temperature of < 40 °C gives (DOTG)2MnBr4 glass unique thermoplastic properties, allowing it to conform to irregularly shaped objects and reduce the distortion in X‐ray imaging.
Structure and Properties of Cellulose Strengthened Poly(Acrylic Acid) Hydrogels
Authors: Chen Zihao , Zhao Xuan , Yu Yiruo , Zhou Jinping 
Published: February 2024

AbstractPoly(acrylic acid) (PAAc) hydrogels are essential functional materials. However, their mechanical properties do not meet the required standards. In this study, a one‐pot method is employed to prepare cellulose‐reinforced PAAc hydrogels by dissolving allyl cellulose (AC) in acrylic acid (AAc) solutions. Fourier transform infrared (FTIR), solid‐state 13C nuclear magnetic resonance (NMR), and thermogravimetric (TG) analysis are used to demonstrate that the incorporation of AC results in the formation of covalent and hydrogen bonds, which contribute to the crosslink network of the PAAc hydrogels. Significantly, by modifying the ratio of AC to AAc in the pre‐polymerization solution, the prepared AC–PAAc hydrogels exhibit a transition from transparent to opaque. This suggests that phase separation is induced by hydrogen bonding. The occurrence of phase separation is verified by observing the hydrogel microstructures using scanning electron microscopy. Phase separation leads to enhanced polymer–polymer interactions in the hydrogels, resulting in a maximum fracture stress of 2.34 MPa. The AC–PAAc hydrogels display distinct swelling behavior under various pH conditions. Moreover, they demonstrate differences in transparency and mechanical properties when exposed to dimethyl sulfoxide (DMSO) and water, indicating their responsiveness to solvents. This work demonstrates the great potential of enhancing the mechanical performance and responsiveness of PAAc hydrogels.
Brown Adipose Tissue, Batokines, and Bioactive Compounds in Foods: An Update
Authors: Martins Fabiane Ferreira , Martins Bruna Cadete , Teixeira Ananda Vitoria Silva , Ajackson Matheus , Souza‐Mello Vanessa , Daleprane Julio Beltrame 
Published: February 2024

AbstractThe discovery of metabolically active brown adipose tissue (BAT) in human adults and the worldwide increase in obesity and obesity‐related chronic noncommunicable diseases (NCDs) has made BAT a therapeutic target in the last two decades. The potential of BAT to oxidize fatty acids rapidly and increase energy expenditure inversely correlates with adiposity, insulin and glucose resistance, and cardiovascular and metabolic diseases. Currently, BAT is recognized by a new molecular signature; several BAT‐derived molecules that act positively on target tissues have been identified and collectively called batokines. Bioactive compounds present in foods are endowed with thermogenic properties that increase BAT activation signaling. Understanding the mechanisms that lead to BAT activation and the batokines secreted by it within the thermogenic state is fundamental for its recruitment and management of obesity and NCDs. This review contributes to recent updates on the morphophysiology of BAT, its endocrine role in obesity, and the main bioactive compounds present in foods involved in classical and nonclassical thermogenic pathways activation.
Research on the reasonable sample dimension of woven composites in split Hopkinson pressure bar testing
Authors: Yu Jikai , Huang Jinzhao , Zhang Li , Yu Shangyang , Guo Licheng 
Published: February 2024

AbstractAn experimental design method is proposed to guide the selection of specimen dimension and split Hopkinson pressure bar apparatus. This method is applicable to the woven composite with modulus independent of strain rate. This method can predict the maximum specimen dimension at the desired strain rate under the maximum strike velocity of the apparatus. Based on the proposed design method, the in‐plane dynamic compressive behavior of 2D plain weave carbon/aramid hybrid composite was obtained. The strength exhibited sensitive to strain rates. The nonlinear constitutive model described the dynamic constitutive relationship effectively. The distribution of delamination failure significantly influenced the final failure shape of the specimens through the high‐velocity camera. Microscopic observations indicated that carbon fiber yarns and aramid fiber yarns exhibited different fracture modes.Highlights
An experimental design method applicable to woven composites in dynamic tests.
Negative correlation between strength and strain rate of hybrid composites.
The validity of the nonlinear constitutive model to dynamic property.
The effect of hybridization and strain rates on damage modes.
Advancing rare cancer research by MALDI mass spectrometry imaging: Applications, challenges, and future perspectives in sarcoma
Authors: Stillger Maren Nicole , Li Mujia Jenny , Hönscheid Pia , von Neubeck Cläre , Föll Melanie Christine 
Published: February 2024

AbstractMALDI mass spectrometry imaging (MALDI imaging) uniquely advances cancer research, by measuring spatial distribution of endogenous and exogenous molecules directly from tissue sections. These molecular maps provide valuable insights into basic and translational cancer research, including tumor biology, tumor microenvironment, biomarker identification, drug treatment, and patient stratification. Despite its advantages, MALDI imaging is underutilized in studying rare cancers. Sarcomas, a group of malignant mesenchymal tumors, pose unique challenges in medical research due to their complex heterogeneity and low incidence, resulting in understudied subtypes with suboptimal management and outcomes.In this review, we explore the applicability of MALDI imaging in sarcoma research, showcasing its value in understanding this highly heterogeneous and challenging rare cancer. We summarize all MALDI imaging studies in sarcoma to date, highlight their impact on key research fields, including molecular signatures, cancer heterogeneity, and drug studies. We address specific challenges encountered when employing MALDI imaging for sarcomas, and propose solutions, such as using formalin‐fixed paraffin‐embedded tissues, and multiplexed experiments, and considerations for multi‐site studies and digital data sharing practices.Through this review, we aim to spark collaboration between MALDI imaging researchers and clinical colleagues, to deploy the unique capabilities of MALDI imaging in the context of sarcoma.
Asymptotically‐Flat Black Hole Solutions in Symmergent Gravity
Authors: Puliçe Beyhan , Pantig Reggie C. , Övgün Ali , Demir Durmuş 
Published: February 2024

AbstractSymmergent gravity is an emergent gravity model with an curvature sector and an extended particle sector having new particles beyond the known ones. With constant scalar curvature, asymptotically flat black hole solutions are known to have no sensitivity to the quadratic curvature term (coefficient of ). With variable scalar curvature, however, asymptotically‐flat symmergent black hole solutions turn out to explicitly depend on the quadratic curvature term. In the present work, asymptotically‐flat symmergent black holes with variable scalar curvature are constructed and used its evaporation, shadow, and deflection angle to constrain the symmergent gravity parameters. Concerning their evaporation, new particles predicted by symmergent gravity are found, even if they do not interact with the known particles, can enhance the black hole evaporation rate. Concerning their shadow, statistically significant symmergent effects are reached at the level for the observational data of the Event Horizon Telescope (EHT) on the Sagittarius A* supermassive black hole are shown. Concerning their weak deflection angle, discernible features for the boson‐fermion number differences are revealed, particularly at large impact parameters. These findings hold the potential to serve as theoretical predictions for future observations and investigations on black hole properties.
An updated software reliability model using the shanker model and failure data
Authors: Shafiq Anum , Sindhu Tabassum Naz , Lone Showkat Ahmad , Abushal Tahani A. , Hassan Marwa K. H. 
Published: February 2024

AbstractSoftware developers' goal is to develop reliable and superior software. Due to the fact that software errors frequently generate large societal or financial losses, software reliability is essential. Software reliability growth models are a widely used technique for software reliability assessment. This study examines various nonhomogeneous Poisson process models with the newly developed software reliability distribution and evaluates the unknown model parameters based on frequentist and Bayesian methods of estimation. Finally, we conduct evaluations on real datasets using a variety of evaluation criteria to compare the results of previous software reliability growth models and show how the proposed model may be applied under both approaches in a practical setting. According to this study, the innovative model's mean square error,R2, , bias, predicted relative variation, Theil statistic, and mean error of prediction values show the lowest values under the Bayesian approach for data sets II to IV, and both approaches perform well for data set I. These implementation findings demonstrate the effectiveness of our specific approach based on our examination of failure data.
In Situ Spin Polarization Measurement Method and Identification of Optimal Spin Polarization Range in Atomic Magnetometer
Authors: Li Renjie , Zhai Yueyang , Li Jiajie , Cao Qian , Liu Ying 
Published: February 2024

AbstractIn this study, an in situ measurement method of spin polarization in single‐beam atomic magnetometer is presented. Modeling magnetic linewidth by incorporating nonlinear attenuation along the propagation direction of light and employing the output response equation of magnetometers at zero‐field resonance. Utilizing the model for fitting to extract relaxation rate information, the photon absorption cross‐sections at three temperatures are estimated to be , , and , respectively. Further, the spin polarization curves are obtained by introducing the spin polarization equations. Given the diminishing marginal utility resulting from the enhancement of performance through increased spin polarization, long‐term sensitivity is employed to determine optimal spin polarization range. The optimal long‐term sensitivity for four displayed states is (@31.5Hz), while the ultimate minimum sensitivity is 10.7 (@31.5Hz). The optimal spin polarization ranges at three temperatures are 78.9%–87.1%, 82.3%–88.5%, and 84.5%–88.4%, respectively. The measurement method applied to single‐beam magnetometer can be easily extended to multi‐axis vector magnetometer. The determination of optimal spin polarization range is of great significance for the performance and stability of the magnetometer system, improving the sensitivity of magnetic field measurement, and ensuring its widespread application in bio‐magnetic measurement.
Changes in soil profile organic carbon and hydro‐physical properties as impacted by long‐term manure and inorganic fertilizer rates under a corn–soybean rotation system
Authors: Sangotayo Anuoluwa O. , Chakraborty Poulamee , Sekeran Udayakumar , Xu Sutie , Kumar Sandeep , Kovacs Peter 
Published: February 2024

AbstractUsing manure appropriately may enhance organic carbon and hydro‐physical properties while avoiding the negative impact on the environment. However, how manure impacts soils, especially at lower depths, is still not well studied. Therefore, the objective of this study was to assess the impact of different manure and inorganic fertilizer application rates on soil profile organic carbon and hydro‐physical properties under corn (Zea mays L.)–soybean (Glycine max L.)–spring wheat (Triticum aestivum L.) rotation at Beresford (established in 2003) and Brookings (established in 2008) sites in South Dakota. The treatments included low manure (LM), medium manure (MM), high manure (HM), medium fertilizer (MF), high fertilizer (HF), and control (CK). Four replicated intact soil cores were collected from all the treatments at 0‐ to 10‐cm, 10‐ to 20‐cm, 20‐ to 30‐cm, and 30‐ to 40‐cm depths. Considering treatments by depth interactions, the LM and MM decreased bulk density (ρb) by 6.9%–22.1%, as compared to the CK at 0–30 cm for either site. The HM decreased ρb by 16.4%–24.7%, as compared to the HF at 30–40 cm for either site. On observing treatment as the main effect, the MM and HM increased the soil water retention (SWR) at 0 and −5 kPa compared to MF, HF, and CK in Brookings, and the MM increased the SWR at −30 kPa as compared to the MF in Beresford at 0‐ to 40‐cm depths. The data suggest that continuous manure application may enhance organic carbon and hydro‐physical properties at lower depths. Therefore, this study concluded that long‐term manure application showed greater improvements when compared to long‐term application of inorganic fertilizer alone. It can improve hydro‐physical properties, thereby stabilizing the soil structure and improving water retention at lower depths.
Effect of water salinity and sodicity on soil least limiting water range
Authors: Safadoust Azadeh , Dashtpeyma Behzad , Mosaddeghi Mohammad Reza , Asgarzadeh Hossein , Gharabaghi Bahram 
Published: February 2024

AbstractThis study aimed to evaluate the effects of water salinity and sodicity on the least limiting water range (LLWR) of two clay loam and sandy loam soils. The undisturbed soil samples were subjected to different water qualities, including three levels of sodium adsorption ratio (SAR, 1, 5, and 12) and electrical conductivity (EC, 1, 6, and 10 dS m−1). Our findings indicate that increasing EC at each SAR led to greater soil water retention. This was attributed to salinity affecting pore size distribution toward smaller pores by altering the diffuse double layer and causing soil particle flocculation. With increasing SAR levels at each EC level, soil water content at the wilting point also rose due to structural changes, clay swelling, and dispersion, resulting in more micropores and increased adsorptive surfaces in the soil. Additionally, soil volumetric water content at a 10% air‐filled porosity decreased, while values at a critical penetration resistance of 2 MPa increased with higher bulk density across all treatments. The LLWR showed a negative correlation with bulk density in clay loam soil across all SAR and EC treatments. The LLWR increased with higher water EC but decreased with increasing water SAR. The highest LLWR was observed at SAR = 1 and EC = 10 dS m−1, while the lowest occurred at SAR = 12 and EC = 1 dS m−1. The results revealed that elevated values of SAR in irrigation water reduced soil water accessibility for plants. However, as irrigation water salinity increased, the detrimental effects of SAR diminished.
Improving soil water storage with no‐till cover cropping in the Mississippi River Alluvial Basin
Authors: Dhakal Madhav , Locke Martin A. , Reddy Krishna N. , Moore Matthew T. , Steinriede R. Wade , Krutz L. Jason 
Published: February 2024

AbstractExcessive tillage reduces soil water storage and increases surface runoff. Cover crops can modify the effect of tillage on soil water dynamics, but limited information is available for the Mississippi River Alluvial Basin. This study was conducted to determine whether soil–water dynamics could be manipulated through conservation production systems affecting surface residue management. Effects of tillage (conventional tillage [CT] vs. no‐tillage [NT]) and cover cropping (no cover crop and Austrian pea [Pisum sativum L.] cover crop [CC]) on soil water balance during the CC season in sorghum (Sorghum bicolor L.) and cotton (Gossypium hirsutum L.) crops were modeled using the root zone water quality model for a site near Stoneville, MS, on “Commerce” silty‐loam soil. Capacitance sensors measured soil volumetric water content to 120 cm during CC growth in 2019 and 2020. Field calibration of sensors reduced root mean square error from 0.05 to 0.03 m3 m−3. Pooled across years, NT increased volumetric water content in the 0–40 and 40–120 soil layers by 8.5% and 6.8%, respectively, compared to CT. Regardless of the CC treatment and cropping system, NT reduced surface runoff by 24.5% over its conventional counterpart, while soil water storage increased from 2.35 to 5.23 cm within the 1.2‐m profile, resulting in a 17% increase in consumptive use of water (evapotranspiration). CC treatments did not impact soil water storage and consumptive water use. The results demonstrate that NT systems can affect water dynamics by increasing infiltration and soil water storage in the humid subtropical region of the United States.
Analyzing three Zeros (zero poverty, unemployment, and carbon emissions) in Asia and the Pacific region: Assessment of sustainable development goals through the STIRPAT model
Authors: Khan Muhammad Azam 
Published: February 2024

AbstractPoverty, unemployment, and environmental degradation are growing issues and significant challenges to sustainable development. They are visible obstacles to achieving the United Nations Sustainable Development Goals (SDGs). The three ZEROS (zero net carbon emissions, zero poverty, and zero unemployment) within the SDGs have not yet been thoroughly explored and need to be empirically examined. This is the primary aim of this study, which focuses on 10 developing countries in Asia & the Pacific. The study utilized panel data from 1997 to 2021 and a stochastic impact by regression on population, affluence, and technology (STIRPAT) model and implemented the second‐generation panel unit root test, cross‐sectional augmented autoregressive distributed lags (CS‐ARDL), panel fully modified ordinary least squares (FMOLS) approaches, and panel Granger‐causality test. The empirical results of the CS‐ARDL approach vindicate that poverty contributes to the environmental deterioration proxied by CO2 emissions, while the unemployment rate inhibits the environmental damage. The other regressors, namely national income by real gross domestic product per capita, energy use, and population are harming the environment, while technological innovation and digitalization reduce environmental degradation. These results are re‐corroborated by implementing the FMOLS estimator. The Granger causality results reveal a bidirectional causality between poverty and environmental degradation. Therefore, it is essential for management authorities to implement pragmatic public policies that focus on sustainable development strategies, such as investing in education and stimulating sustainable economic growth. This will help to reduce unemployment, improve living standards, decrease poverty, and ultimately achieve the Three Zeros Club initiative and sustainable development goals.