bluuebunny/crossref_metadata_2025_split huggingface dataset:
Development and Scale up of Preparative HIC for the Purification of a Recombinant Therapeutic Protein
Authors: Graumann K. , Ebenbichler A. A. 
Published: November 2005

AbstractIn the biopharmaceutical industry, process development has to overcome the paradox between increasing demands on product quality and aggressive overall development time lines. Streamlining development and scale‐up has become a requirement in order to cope with these constraints. Hydrophobic interaction chromatography (HIC) has gained popularity as an efficient tool in downstream process development, which represents an orthogonal method compared to other widely used chromatography principles. Thus, host cell protein (HCP) removal combined with the separation of product variants based on subtle differences in hydrophobicity are major strengths of this separation technique. The development and scale‐up of a preparative HIC step for a therapeutic protein for human use is described. Issues like the removal of product‐ and process‐related impurities have been addressed. The direct transferability of the results, from scale‐down optimization experiments via the pilot scale to the final production scale, clearly show the robustness and power of HIC in this process context.
Potential for Using Histidine Tags in Purification of Proteins at Large Scale
Authors: Gaberc‐Porekar V. , Menart V. 
Published: November 2005

AbstractAttachment of oligo‐histidine tag (His‐tag) to the protein N‐ or C‐terminus is a good example of early and successful protein engineering to design a unique and generalized purification scheme for virtually any protein. Thus relatively strong and specific binding of His‐tagged protein is achieved on an Immobilized Metal‐Ion Affinity Chromatography (IMAC) matrix. Most popular hexa‐histidine tag and recently also deca‐histidine tag are used in combination with three chelating molecules: iminodiacetic acid (IDA), nitrilotriacetic acid (NTA), and carboxymethyl aspartic acid (CM‐Asp), covalently attached to the chromatographic matrix. The following combinations with divalent metal ions are preferentially used: (Cu, Zn, Ni, Co)‐IDA, Ni‐NTA, and Co‐CM‐Asp. At large scale, regarding cost and product purity, a decisive step is precise and efficient cleavage of His‐tag by the cleavage enzyme. Two‐step IMAC followed by a polishing step appears to be a minimum but still realistic as an approach to generic technology also for more demanding products. Possible drawbacks in using His‐tags and IMAC, such as leaching of metal ions, inefficient cleavage, and batch‐to‐batch reproducibility must be carefully evaluated before transferred to large scale. Although a great majority of reports refer to small laboratory scale isolations for research purposes it appears there is much higher potential for more extensive use of His‐tags and IMAC at large scale than currently documented.
Noninvasive Methods for Characterization of Large‐Volume Monolithic Chromatographic Columns
Authors: Podgornik A. , Vidič J. , Jančar J. , Lendero N. , Frankovič V. , Štrancar A. 
Published: November 2005

AbstractChromatographic monoliths exhibit several properties like flow‐unaffected resolution and dynamic binding capacity, low pressure drop and high capacity for extremely large molecules, which are advantageous to the purification of large biomolecules such as proteins, DNA or even viruses. Recently, large‐volume monolithic columns were introduced enabling the monoliths to be incorporated into industrial downstream processes. Due to the monolithic structure, however, conventional methods for resin characterization cannot be applied to monoliths, which limit their usage under cGMP conditions. In this article, a methodology of how to overcome this problem and to determine the most important parameters is presented. Several fast and noninvasive methods for monolith characterization are introduced. Their usage enables accurate determination of monolith pore size distribution and specific surface area, uniformity of the monolith as well as type and density of the active groups before or during monolith usage.
Desensitizing models using covariance matrix transforms or counter‐balanced distortions
Authors: DiFoggio Rocco 
Published: November 2005

AbstractThis paper presents a generalization of the Lagrange multiplier equation for a regression subject to constraints. It introduces two methods for desensitizing models to anticipated spectral artifacts such as baseline variations, wavelength shift, or trace contaminants. For models derived from a covariance matrix such as multiple linear regression (MLR) and principal components regression (PCR) models, the first method shows how a covariance matrix can be desensitized to an artifact spectrum, v, by adding σ2 v ⊗ v to it. For models not derived from a covariance matrix, such as partial least squares (PLS) or neural network (NN) models, the second method shows how distorted copies of the original spectra can be prepared in a counter‐balanced manner to achieve desensitization. Unlike earlier methods that added random distortions to spectra, these new methods never introduce any accidental correlations between the added distortions and the Y‐block. The degree of desensitization is controlled by a parameter, σ, for each artifact from zero (no desensitization) to infinity (complete desensitization, which is the Lagrange multiplier limit). Unlike Lagrange multipliers, these methods permit partial desensitization so we can individually vary the degree of desensitization to each artifact, which is important when desensitization to one artifact inhibits desensitization to another. Copyright © 2005 John Wiley & Sons, Ltd.
Decacyclene as Complexation Manifold: Synthesis, Structure and Properties of Its Fe2 and Fe4 Slipped Triple‐Decker Complexes
Authors: Schneider Jörg J. , Spickermann Dirk , Lehmann Christian W. , Magull Jörg , Krüger Hans‐Jörg , Ensling Jürgen , Gütlich Philipp 
Published: November 2005

AbstractReaction of [(η5‐Me4EtC5)FeIICl(tmeda)] (tmeda=N,N,N′N′‐tetramethylethylenediamine) with a polyanion solution of decacyclene (1) results in the formation of the triple‐deckers [{(η5‐Me4EtC5)Fe}2‐μ2‐(η6:η6‐decacyclene)] (3) and [{(η5‐Me4EtC5)Fe}4‐μ4‐(η6:η6:η6:η6‐decacyclene)] (4). Metal complexation in 3 and 4 occurs on opposite faces of the π perimeter in an alternating mode. The decacyclene ring adopts a gently twisted molecular propeller geometry with twofold crystallographic symmetry (C2). Complex 4 crystallizes in the chiral space group C2221; the investigated crystal only contains decacyclene rings with M chirality. The handedness can be assigned unambiguously to the presence of the iron atoms. Cyclovoltammetric studies revealed quasireversible behavior of the redox events and a strong interaction of the Fe atoms in 3 and 4, exemplified by potential differences ΔE of 660 and 770(780) mV between the first and the second individual oxidation processes. This corresponds to a high degree of metal–metal interaction for 3 and 4. The sucesssful syntheses of 3 and 4 together with earlier results from our laboratory proves that all five‐ and six‐membered π subunit sets of 1 are prone to metal complexation. A clear site preference in 1 towards the complexation of [CpR]iron, ‐cobalt, and ‐nickel fragments exists.
A Designed Well‐Folded Monomeric Four‐Helix Bundle Protein Prepared by Fmoc Solid‐Phase Peptide Synthesis and Native Chemical Ligation
Authors: Dolphin Gunnar T. 
Published: November 2005

AbstractThe design and total chemical synthesis of a monomeric native‐like four‐helix bundle protein is presented. The designed protein, GTD‐Lig, consists of 90 amino acids and is based on the dimeric structure of the de novo designed helix‐loop‐helix GTD‐43. GTD‐Lig was prepared by the native chemical ligation strategy and the fragments (45 residues long) were synthesized by applying standard fluorenylmethoxycarbonyl (Fmoc) chemistry. The required peptide–thioester fragment was prepared by anchoring the free γ‐carboxy group of Fmoc‐Glu‐allyl to the solid phase. After chain elongation the allyl moiety was orthogonally removed and the resulting carboxy group was functionalized with a glycine–thioester followed by standard trifluoroacetic acid (TFA) cleavage to produce the unprotected peptide–thioester. The structure of the synthetic protein was examined by far‐ and near‐UV circular dichroism (CD), sedimentation equilibrium ultracentrifugation, and NMR and fluorescence spectroscopy. The spectroscopic methods show a highly helical and native‐like monomeric protein consistent with the design. Heat‐induced unfolding was studied by tryptophan absorbance and far‐UV CD. The thermal unfolding of GTD‐Lig occurs in two steps; a cooperative transition from the native state to an intermediate state and thereafter by noncooperative melting to the unfolded state. The intermediate exhibits the properties of a molten globule such as a retained native secondary structure and a compact hydrophobic core. The thermodynamics of GuHCl‐induced unfolding were evaluated by far‐UV CD monitoring and the unfolding exhibited a cooperative transition that is well‐fitted by a two‐state mechanism from the native to the unfolded state. GTD‐Lig clearly shows the characteristics of a native protein with a well‐defined structure and typical unfolding transitions. The design and synthesis presented herein is of general applicability for the construction of large monomeric proteins.
Synthesis of ansa‐[n]Silacyclopentadienyl–Cycloheptatrienyl–Chromium Complexes (n = 1, 2): Novel Precursors for Polymers Bearing Chromium in the Backbone
Authors: Bartole‐Scott Alexandra , Braunschweig Holger , Kupfer Thomas , Lutz Matthias , Manners Ian , Nguyen Thi‐loan , Radacki Krzysztof , Seeler Fabian 
Published: November 2005

AbstractReaction of [(η5‐C5H4Li)(η7‐C7H6Li)Cr]⋅tmeda with a variety of dialkyl(dichloro)silanes in aliphatic solvents afforded the corresponding [1]silatrochrocenophanes. Structural characterization by X‐ray diffraction analysis of the [1]silatrochrocenophanes bearing Me2Si, (iPr)2Si, and silacyclobutane bridges revealed tilt angles α of 15.56(12)°, 15.8(1)°, and 16.33(17)°, respectively. Analogously, a [2]silatrochrocenophane (6) was prepared in excellent yield by reaction of [(η5‐C5H4Li)(η7‐C7H6Li)Cr]⋅tmeda with 1,2‐dichloro‐1,1,2,2‐tetramethyldisilane. This complex also was characterized structurally and exhibited a tilt angle α of 2.60(15)°. The [1]silatrochrocenophane bearing the Me2Si bridge underwent facile and regioselective carbon–silicon bond cleavage with [Pt(PEt3)4] to give a very high yield of an oxidative addition product. The ring‐opening polymerization of these novel [1]silatrochrocenophanes afforded ring‐opened chromium‐based polymers.
Synthesis and Structure of Novel Organocycloborates
Authors: Braunschweig Holger , D'Andola Giovanni , Welton Tom , White Andrew J. P. 
Published: November 2005

AbstractA series of α,ω‐boryl(bromo)alkanes of the general formula R2B(CH2)nBr (n=3, 4, 5, 6) was obtained in high yield following a standard hydroboration protocol. Upon treatment with Mg turnings and formation of the respective Grignard species, all alkanes with n=4 to 6 underwent an unprecedented boron‐centered cyclisation reaction with formation of boratacyclopentanes, ‐hexanes, and ‐heptanes, respectively. All new compounds were isolated in high yields as colourless, crystalline materials and characterised in solution by multinuclear NMR spectroscopy. Four representative examples were chosen for X‐ray diffraction studies, thus providing the first structurally characterised ring systems of that size at a tetraalkyl borate centre.
On the Rigidity of Polynorbornenes with Dipolar Pendant Groups
Authors: Lin Wei‐Yu , Murugesh Modachur G. , Sudhakar Sundarraj , Yang Hsiao‐Ching , Tai Hwan‐Ching , Chang Chia‐Seng , Liu Yi‐Hung , Wang Yu , Chen I‐Wen Peter , Chen Chun‐hsien , Luh Tien‐Yau 
Published: November 2005

AbstractA range of polynorbornenes (PNBs) with fused dipolar pendant groups at C‐5,6 positions was synthesized by ring‐opening metathesis polymerization catalyzed by a ruthenium carbene complex (Grubbs I). Photophysical studies, EFISH measurements, and atomic force microscopy images have been used to investigate the structures and morphology of these polymers. These results suggest that the polymers may adopt rigid rod‐like structures. The presence of the double bonds in PNBs appeared to be indispensable for the rigidity of the polymers. Interaction between unsaturated pendant groups may result in coherent alignment leading to a rod‐like structure.
A Mechanistic and Kinetic Study of the Formation of Metal Nanoparticles by Using Synthetic Tyrosine‐Based Oligopeptides
Authors: Si Satyabrata , Bhattacharjee Rama Ranjan , Banerjee Arindam , Mandal Tarun K. 
Published: November 2005

AbstractSynthetic oligopeptides containing redox‐active tyrosine residues have been employed to prepare gold and silver nanoparticles. In this reduction process an electron from the tyrosinate ion of the peptide is transferred to the metal ion at basic pH through the formation of a tyrosyl radical, which is eventually converted to its dityrosine form during the reaction. This reaction mechanism was confirmed from UV‐visible, fluorescence, and EPR spectroscopy and was found to be pH‐dependent. Transmission electron microscopy measurement shows that the average size and the monodispersity of gold nanoparticles increase as the number of tyrosine residues in the peptide increases. The kinetic study, based on spectrophotometric measurements of the surface plasmon resonance optical property, shows that the rate of formation of gold nanoparticles was much faster at higher pH than at lower pH and was also dependent on the number of tyrosine residues present in the peptide. The dityrosine form of the peptide was found to retain reducing properties like those of tyrosine in basic medium.
Fine Tuning of the Electronic Properties of Linear π‐Conjugated Oligomers by Covalent Bridging
Authors: Blanchard Philippe , Verlhac Patrick , Michaux Laurent , Frère Pierre , Roncali Jean 
Published: November 2005

AbstractA series of oligothienylenevinylenes, π‐conjugated oligomers rigidified by ethylene bridges attached at different sites of the conjugated backbone, have been constructed by multistep synthetic methodologies. Electronic absorption spectra show that the rigidification of the conjugated system produces a bathochromic shift of the absorption maximum and a narrowing of the HOMO–LUMO energy gap, as compared to the spectra of an open‐chain reference compound. The cyclic voltammograms of all oligomers show that these compounds can be reversibly oxidized into their cation radicals and dications and that rigidification produces a large negative shift of the first oxidation potential, which is indicative of a considerable increase of the HOMO level. Electrochemical data confirm that covalent bridging strongly affects the HOMO and LUMO levels and these data demonstrate that the sites of fixation of the bridges on the π‐conjugated backbone exert a determining effect on the relative stability of the cation radical and dication. Examination of these various results in the light of theoretical calculations shows that in addition to a local control of bond length alternation, and hence of the HOMO–LUMO gap, the fixation of covalent bridges at selected positions of the π‐conjugated system limits the deformation of the π‐conjugated structure upon oxidation to the charged states.
Domino Reactions of 1,3‐Bis‐Silyl Enol Ethers with Benzopyrylium Triflates: Efficient Synthesis of Fluorescent 6H‐Benzo[c]chromen‐6‐ones, Dibenzo[c,d]chromen‐6‐ones, and 2,3‐Dihydro‐1H‐4,6‐dioxachrysen‐5‐ones
Authors: Appel Bettina , Saleh Nehad N. R. , Langer Peter 
Published: November 2005

AbstractThe condensation of 1,3‐bis‐silyl enol ethers with benzopyrylium triflates, generated in situ by the reaction of chromones with Me3SiOTf, afforded functionalized 2,3‐dihydrobenzopyrans; treatment of the latter with NEt3 or BBr3 resulted in a domino retro‐Michael–aldol–lactonization reaction and the formation of a variety of 7‐hydroxy‐6H‐benzo[c]chromen‐6‐ones. The hydroxy group was functionalized by using Suzuki cross‐coupling reactions. The methodology reported was applied to the synthesis of the natural product autumnariol and a new fluorescence dye, which exhibits promising optical properties. 2,3‐Dihydro‐1H‐4,6‐dioxachrysen‐5‐ones were prepared by condensation of chromones with 1,3‐bis‐silyl enol ethers containing a remote chloride group, domino retro‐Michael–aldol–lactonization, and an intramolecular Williamson reaction.
Octahedral Hexahydroxo Rhenium Cluster Complexes [Re6Q8(OH)6]4‐ (Q: S, Se): Synthesis, Structure, and Properties.
Authors: Yarovoi Spartak S. , Mironov Yuri V. , Naumov Dmitry Y. , Gatilov Yuri V. , Kozlova Svetlana G. , Kim Sung‐Jin , Fedorov Vladimir E. 
Published: November 2005

AbstractFor Abstract see ChemInform Abstract in Full Text.
Improvement of Fluorescence Characteristics of Coumarins: Syntheses and Fluorescence Properties of 6‐Methoxycoumarin and Benzocoumarin Derivatives as Novel Fluorophores Emitting in the Longer Wavelength Region and Their Application to Analytical Reagents.
Authors: Murata Chiyomi , Masuda Toshinobu , Kamochi Yasuko , Todoroki Kenichiro , Yoshida Hideyuki , Nohta Hitoshi , Yamaguchi Masatoshi , Takadate Akira 
Published: November 2005

AbstractFor Abstract see ChemInform Abstract in Full Text.
Regio‐ and Stereochemical Aspects in Synthesis of 2‐Allyl Derivatives of Glycolic, Mandelic and Lactic Acids and Their Iodocyclizations to 3‐Hydroxy‐3,4‐dihydrofuran‐2(5H)‐ones.
Authors: Kaur Pervinder , Singh Palwinder , Kumar Subodh 
Published: November 2005

AbstractFor Abstract see ChemInform Abstract in Full Text.
Selective Reduction of Nitrocinnamoylfumagillols with α,β‐Unsaturated Ester Using Borohydride Exchange Resin (BER)‐Nickel Acetate.
Authors: Lee Hong Woo , Ahn Joong Bok , Lee Jung Hwa , Kang Sung Kwon , Ahn Soon Kil , Lee Sang Joon 
Published: November 2005

AbstractFor Abstract see ChemInform Abstract in Full Text.
Microwave‐Assisted Decarboxylation of Bicyclic 2‐Pyridone Scaffolds and Identification of Aβ‐Peptide Aggregation Inhibitors.
Authors: Aaberg Veronica , Norman Fredrik , Chorell Erik , Westermark Andreas , Olofsson Anders , Sauer‐Eriksson A. Elisabeth , Almquist Fredrik 
Published: November 2005

AbstractFor Abstract see ChemInform Abstract in Full Text.
Formal Alkyne Insertion into Alkoxycarbene Complexes: Simple Access to Enantiopure Group 6 Alkynyl(alkoxy)carbene Complexes.
Authors: Barluenga Jose , de la Rua Ramon Bernardo , de Saa Diana , Ballesteros Alfredo , Tomas Miguel 
Published: November 2005

AbstractFor Abstract see ChemInform Abstract in Full Text.
Gallium‐Mediated Allyl Transfer from Bulky Homoallylic Alcohol to Aldehydes via Retro‐Allylation: Stereoselective Synthesis of Both erythro‐ and threo‐Homoallylic Alcohols.
Authors: Hayashi Sayuri , Hirano Koji , Yorimitsu Hideki , Oshima Koichiro 
Published: November 2005

AbstractFor Abstract see ChemInform Abstract in Full Text.
Ring Opening of 2‐(Bromomethyl)‐1‐sulfonylaziridines Towards 1,3‐Heteroatom Substituted 2‐Aminopropane Derivatives.
Authors: D'hooghe Matthias , Rottiers Mario , Kerkaert Inge , De Kimpe Norbert 
Published: November 2005

AbstractFor Abstract see ChemInform Abstract in Full Text.
Electrooxidative Conversion of Dibenzoylbenzene Dihydrazones into the Corresponding Bis‐Diazo Compounds and Bis‐Dimethyl Acetals.
Authors: Okimoto Mitsuhiro , Numata Kaori , Tomozawa Kenta , Shigemoto Takamasa , Hoshi Masayuki , Takahashi Yukio 
Published: November 2005

AbstractFor Abstract see ChemInform Abstract in Full Text.
Electrophilic Substitution in Aromatic and Heteroaromatic Substrates by Trichlorocyclopropenylium Tetrachloroaluminate.
Authors: Skornyakov Yu. V. , Lozinskaya N. A. , Proskurnina M. V. , Zefirov N. S. 
Published: November 2005

AbstractFor Abstract see ChemInform Abstract in Full Text.
Design, Synthesis, and Evaluation of 2‐Phenoxy‐indan‐1‐one Derivatives as Acetylcholinesterase Inhibitors.
Authors: Sheng Rong , Lin Xiao , Li Jingya , Jiang Yanke , Shang Zhicai , Hu Yongzhou 
Published: November 2005

AbstractFor Abstract see ChemInform Abstract in Full Text.
Lewis Acid Catalyzed Asymmetric Radical Additions of Trialkylboranes to (1R,2S,5R)‐2‐ (1‐methyl‐1‐phenylethyl)‐5‐methylcyclohexyl‐2H‐azirine‐3‐carboxylate.
Authors: Risberg Erik , Fischer Andreas , Somfai Peter 
Published: November 2005

AbstractFor Abstract see ChemInform Abstract in Full Text.
Efficient Synthesis of Novel γ‐Substituted γ‐Butenolides by Lewis Acid Catalyzed Addition of Metal Enolates of Active Methylene Compounds to Mucohalic Acids.
Authors: Zhang Ji , Sarma Koushik Das , Curran Timothy T. , Belmont Daniel T. , Davidson James G. 
Published: November 2005

AbstractFor Abstract see ChemInform Abstract in Full Text.
Synthesis, Characterization, and Intramolecular Diels—Alder Reaction Tandem Dehydroaromatization of a Diene‐diyne.
Authors: Liu Shu‐Zhi , Tang Guang‐Shi , Wang Jing , Li Xue‐Hua 
Published: November 2005

AbstractFor Abstract see ChemInform Abstract in Full Text.
Synthesis of 2‐Azaspiro[4.4]nonan‐1‐ones via Phosphine‐Catalyzed [3 + 2]‐Cycloadditions.
Authors: Yong Sarah R. , Williams Morwenna C. , Pyne Stephen G. , Ung Alison T. , Skelton Brian W. , White Allan H. , Turner Peter 
Published: November 2005

AbstractFor Abstract see ChemInform Abstract in Full Text.
1‐Pentyl‐3‐phenylacetylindoles, a New Class of Cannabimimetic Indoles.
Authors: Huffman John W. , Szklennik Paul V. , Almond Amanda , Bushell Kristen , Selley Dana E. , He Hengjun , Cassidy Michael P. , Wiley Jenny L. , Martin Billy R. 
Published: November 2005

AbstractFor Abstract see ChemInform Abstract in Full Text.
Imidazo[5,1‐b]thiazol‐3‐ones/thiazin‐4‐ones: Synthesis and Reactivity Investigation for Library Generation.
Authors: Le Bas Marie‐Delphine H. , McKinley Neola F. , Hogan Anne‐Marie L. , O'Shea Donal F. 
Published: November 2005

AbstractFor Abstract see ChemInform Abstract in Full Text.
Synthesis of Hantzsch 1,4‐Dihydropyridines under Solvent‐Free Conditions Using Zn[(L)proline]2 as Lewis Acid Catalyst.
Authors: Sivamurugan V. , Kumar R. Suresh , Palanichamy M. , Murugesan V. 
Published: November 2005

AbstractFor Abstract see ChemInform Abstract in Full Text.
New HIV‐1 Replication Inhibitors of the Styryquinoline Class Bearing Aroyl/Acyl Groups at the C‐7 Position: Synthesis and Biological Activity.
Authors: Normand‐Bayle Marie , Benard Christophe , Zouhiri Fatima , Mouscadet Jean‐Francois , Leh Herve , Thomas Claire‐Marie , Mbemba Gladys , Desmaele Didier , d'Angelo Jean 
Published: November 2005

AbstractFor Abstract see ChemInform Abstract in Full Text.
Synthesis of Pyrrolo[3,4‐c]quinolines by 1,5‐Electrocyclization of Non‐Stabilized Azomethine Ylides.
Authors: Nyerges Miklos , Pinter Aron , Viranyi Andrea , Blasko Gabor , Toeke Laszlo 
Published: November 2005

AbstractFor Abstract see ChemInform Abstract in Full Text.
Procedure for the Parallel Preparation of 3‐Imidazo[1,2‐a]pyridin‐3‐yl‐propionic Acid Derivatives Involving Meldrum′s Acid.
Authors: Gerencser Janos , Panka Gabor , Nagy Tamas , Egyed Orsolya , Dorman Gyoergy , Uerge Laszlo , Darvas Ferenc 
Published: November 2005

AbstractFor Abstract see ChemInform Abstract in Full Text.
Synthesis and Mesomorphic Properties of 5‐[4‐(Alkyloxy)phenyl]‐2‐{4′‐[(S)‐2‐methylbutyl]phenyl}pyrimidine (VI)
Authors: Park Seung‐Un , Lee Chan‐Jae , Han Jin Hee 
Published: November 2005

AbstractFor Abstract see ChemInform Abstract in Full Text.
Heterocyclic Synthesis: A Convenient Route to Some 2‐Mercapto 1,3,4‐Oxadiazole and Green Chemistry Microwave‐Induced One‐Pot Synthesis of 2‐Aryl 1,3,4‐Oxadiazole in Quinazolone and Their Antibacterial and Antifungal Activity.
Authors: Desai A. R. , Desai K. R. 
Published: November 2005

AbstractFor Abstract see ChemInform Abstract in Full Text.
Reaction of 2‐[(E)‐Styryl]quinazolin‐4(3H)‐one with Acetylenic Esters: Formation of Unexpected N‐3 Alkenylation Products.
Authors: Chatterjee Tapasi , Chattopadhyay Subhagata , Mukhopadhyay Ranjan , Achari Basudeb , Chakraborty Santu , Mukherjee Alok K. 
Published: November 2005

AbstractFor Abstract see ChemInform Abstract in Full Text.