bluuebunny/crossref_metadata_2025_split huggingface dataset:
Degradation of the neonicotinoid pesticide imidacloprid by electrocoagulation and ultrasound
Authors: Halkijevic Ivan , Licht Katarina , Kosar Vanja , Bogdan Lucija 
Published: April 2024

AbstractImidacloprid is still a widely used neonicotinoid insecticide that is banned in many countries because of the associated environmental risks. Due to the inefficiency of conventional wastewater treatments for pesticide removal, new treatment methods are being investigated. Electrochemical methods, including electrocoagulation (EC), seem to be promising alternatives considering their effectiveness in removing various pollutants from wastewater. The aim of this study was to investigate the effects of electrode material, current density, ultrasound, and operation time on the efficiency of imidacloprid removal from a model solution by EC. The combination of aluminum electrodes and 20 A of applied current for 20 min resulted in total imidacloprid degradation. A simplified energy balance was introduced as a form of process evaluation. Combining ultrasound with EC resulted in 7% to 12% greater efficacy than using only EC.
Association between holiday and weekend admissions and mortality outcomes among patients with acute myocardial infarction receiving percutaneous coronary intervention in Taiwan
Authors: Liu Peter Pin-Sung , Chang Huai-Ren , Hsu Jin-Yi , Huang Huei-Kai , Loh Ching-Hui , Yeh Jih-I 
Published: April 2024

AbstractThere is a lack of studies that concurrently differentiate the effect of the holiday season from the weekend effect on mortality risk in patients with acute myocardial infarction (AMI). We evaluated the mortality risk among patients admitted with AMI who underwent percutaneous coronary intervention, using data from the Taiwan National Health Insurance Research Database. Adult AMI patients admitted during January and February between 2013 and 2020 were enrolled and classified into the holiday season (using the Chinese New Year holiday seasons as an indicator) (n = 1729), weekend (n = 4725), and weekday (n = 14,583) groups according to the first day of admission. A multivariable logistic regression model was used to assess the risk. With the weekday group or the weekend group as the reference, the holiday season group did not have increased risks of in-hospital mortality (adjusted odds ratio [aOR] 1.15; 95% confidence intervals [CI] 0.93–1.42 or aOR 1.23; 95% CI 0.96–1.56) and 7-day mortality (aOR 1.20; 95% CI 0.90–1.58 or aOR 1.24; 95% CI 0.90–1.70). Stratified and subgroup analyses showed similar trends. We conclude that holiday season-initiated admissions were not associated with higher mortality risks in AMI admission cases than weekday or weekend admissions.
Assessing causal relationships between gut microbiota and psoriasis: evidence from two sample Mendelian randomization analysis
Authors: Li Yuan , Chen Gaihe , Hu Xiaohuan , Bao Yunlei , Wu Chuyan , Zeng Ni , Jiang Feng 
Published: April 2024

AbstractMounting data hints that the gut microbiota's role may be pivotal in understanding the emergence of psoriasis. However, discerning a direct causal link is yet elusive. In this exploration, we adopted a Mendelian randomization (MR) strategy to probe the prospective causal interplay between the gut's microbial landscape and the predisposition to psoriasis. Genetic markers acting as instrumental variables for gut microbiota were extrapolated from a genome-wide association study (GWAS) encompassing 18,340 individuals. A separate GWAS yielded summary data for psoriasis, which covered 337,159 patients and 433,201 control subjects. The primary analysis hinged on inverse variance weighting (IVW). Additional methods like the weighted median approach and MR-Egger regression were employed to validate the integrity of our findings. Intriguing correlations emerged between psoriasis risk and eight specific bacterial traits. To illustrate: Mollicutes presented an odds ratio (OR) of 1.003 with a 95% confidence interval (CI) spanning 1.001–1.005 (p = 0.016), while the family. Victivallaceae revealed an OR of 0.998 with CI values between 0.997 and 0.999 (p = 0.023). Eubacterium (coprostanoligenes group) revealed an OR of 0.997 with CI values between 0.994 and 0.999 (p = 0.027). Eubacterium (fissicatena group) revealed an OR of 0.997 with CI values between 0.996 and 0.999 (p = 0.005). Holdemania revealed an OR of 1.001 with CI values 1–1.003 (p = 0.034). Lachnospiraceae (NK4A136 group) revealed an OR of 0.997 with CI values between 0.995 and 0.999 (p = 0.046). Lactococcus revealed an OR of 0.998 with CI values between 0.996 and 0.999 (p = 0.008). Tenericutes revealed an OR of 1.003 with CI values between 1.001 and 1.006 (p = 0.016). Sensitivity analysis for these bacterial features yielded congruent outcomes, reinforcing statistically significant ties between the eight bacterial entities and psoriasis. This comprehensive probe underscores emerging evidence pointing towards a plausible causal nexus between diverse gut microbiota and the onset of psoriasis. It beckons further research to unravel the intricacies of how the gut's microbial constituents might sway psoriasis's pathogenesis.
Eye and head movements in visual search in the extended field of view
Authors: Stein Niklas , Watson Tamara , Lappe Markus , Westendorf Maren , Durant Szonya 
Published: April 2024

AbstractIn natural environments, head movements are required to search for objects outside the field of view (FoV). Here we investigate the power of a salient target in an extended visual search array to facilitate faster detection once this item comes into the FoV by a head movement. We conducted two virtual reality experiments using spatially clustered sets of stimuli to observe target detection and head and eye movements during visual search. Participants completed search tasks with three conditions: (1) target in the initial FoV, (2) head movement needed to bring the target into the FoV, (3) same as condition 2 but the periphery was initially hidden and appeared after the head movement had brought the location of the target set into the FoV. We measured search time until participants found a more salient (O) or less salient (T) target among distractors (L). On average O’s were found faster than T’s. Gaze analysis showed that saliency facilitation occurred due to the target guiding the search only if it was within the initial FoV. When targets required a head movement to enter the FoV, participants followed the same search strategy as in trials without a visible target in the periphery. Moreover, faster search times for salient targets were only caused by the time required to find the target once the target set was reached. This suggests that the effect of stimulus saliency differs between visual search on fixed displays and when we are actively searching through an extended visual field.
Identifying key risk factors for acute compartment syndrome in tibial diaphysis fracture patients
Authors: An Ming , Jia Ruili , Wu Limei , Ma Leilei , Qi Hui , Long Yubin 
Published: April 2024

AbstractAcute compartment syndrome (ACS) is a severe orthopedic issue that, if left untreated, can result in lasting nerve and muscle damage or even necessitate amputation. The association between admission laboratory blood test indicators and the occurrence of ACS in patients with tibial diaphysis fractures is currently a subject of debate. The objective of this research was to identify the contributing factors for ACS in individuals suffering from tibial diaphysis fractures. In this retrospective study, we collected data on a total of 705 individuals from our hospital, comprising 86 ACS patients and 619 non-ACS patients with tibial diaphysis fractures. These participants were categorized into two distinct groups: the ACS group and the non-ACS group. Despite the inherent limitations associated with retrospective analyses, such as potential biases in data collection and interpretation, we conducted a comprehensive analysis of demographics, comorbidities, and admission lab results. Our analytical approach included univariate analysis, logistic regression, and receiver operating characteristic (ROC) curve analysis techniques, aiming to mitigate these limitations and provide robust findings. The statistical analysis revealed several predictors of ACS, including gender (p = 0.011, OR = 3.200), crush injuries (p = 0.004, OR = 4.622), lactic dehydrogenase (LDH) levels (p < 0.001, OR = 1.003), and white blood cell (WBC) count (p < 0.001, OR = 1.246). Interestingly, the study also found that certain factors, such as falls on the same level (p = 0.007, OR = 0.334) and cholinesterase (CHE) levels (p < 0.001, OR = 0.721), seem to provide a degree of protection against ACS. In order to better predict ACS, the ROC curve analysis was employed, which determined threshold values for LDH and WBC. The established cut-off points were set at 266.26 U/L for LDH and 11.7 × 109 cells per liter for WBC, respectively. Our research has successfully pinpointed gender, crush injuries, LDH levels, and white blood cell (WBC) count as crucial risk factors for the development of ACS in patients experiencing tibial diaphysis fractures. Furthermore, by establishing the cut-off values for LDH and WBC, we have facilitated a more personalized assessment of ACS risk, enabling clinical doctors to implement targeted early interventions and optimize patient outcomes.
Large enhancement of red upconversion luminescence in beta Ba2Sc0.67Yb0.3Er0.03AlO5 phosphor via Mn2+ ions doping for thermometry
Authors: Liu Yongtao , Duan Bin , Zhou Lin , Wu Yuxiang , Wang Fengyi , Ding Changchun , Hu Junshan 
Published: April 2024

AbstractHere, this study reports single-band red upconversion emission in β-Ba2ScAlO5: Yb3+/Er3+ phosphor by doping Mn2+. The optimum concentration of Mn2+ ions in β-Ba2ScAlO5: Yb3+/Er3+ phosphor was 0.20. The intensity of red and green emissions is increased by 27.4 and 19.3 times, respectively. Compared with the samples without Mn2+ ions, the red-green integral strength ratio of β-Ba2ScAlO5: Yb3+/Er3+/Mn2+ sample was significantly increased by 28.4 times, reaching 110.9. The UCL mechanism was explored by analyzing the down-conversion luminescence spectra, absorption spectra, UCL spectra, and upconversion fluorescence lifetime decay curves of Yb3+/Er3+/Mn2+ co-doped β-Ba2ScAlO5. The enhancement of upconversion red light is achieved through energy transfer between defect bands and Er3+ ions, as well as energy transfer between Mn2+ ions and Er3+ ions. In addition, the Mn2+ doped β-Ba2ScAlO5: Yb3+/Er3+ red UCL phosphors have great potential for ambient temperature sensing in the 298–523 K temperature range. The maximum sensitivity of β-Ba2ScAlO5: Yb3+/Er3+/Mn2+ phosphor as a temperature sensor at 523 K is 0.0247 K−1.
An evolutionary timeline of the oxytocin signaling pathway
Authors: Sartorius Alina M. , Rokicki Jaroslav , Birkeland Siri , Bettella Francesco , Barth Claudia , de Lange Ann-Marie G. , Haram Marit , Shadrin Alexey , Winterton Adriano , Steen Nils Eiel , Schwarz Emanuel , Stein Dan J. , Andreassen Ole A. , van der Meer Dennis , Westlye Lars T. , Theofanopoulou Constantina , Quintana Daniel S. 
Published: April 2024

AbstractOxytocin is a neuropeptide associated with both psychological and somatic processes like parturition and social bonding. Although oxytocin homologs have been identified in many species, the evolutionary timeline of the entire oxytocin signaling gene pathway has yet to be described. Using protein sequence similarity searches, microsynteny, and phylostratigraphy, we assigned the genes supporting the oxytocin pathway to different phylostrata based on when we found they likely arose in evolution. We show that the majority (64%) of genes in the pathway are ‘modern’. Most of the modern genes evolved around the emergence of vertebrates or jawed vertebrates (540 - 530 million years ago, ‘mya’), including OXTR, OXT and CD38. Of those, 45% were under positive selection at some point during vertebrate evolution. We also found that 18% of the genes in the oxytocin pathway are ‘ancient’, meaning their emergence dates back to cellular organisms and opisthokonta (3500–1100 mya). The remaining genes (18%) that evolved after ancient and before modern genes were classified as ‘medium-aged’. Functional analyses revealed that, in humans, medium-aged oxytocin pathway genes are highly expressed in contractile organs, while modern genes in the oxytocin pathway are primarily expressed in the brain and muscle tissue.
The CBS/H2S signalling pathway regulated by the carbon repressor CreA promotes cellulose utilization in Ganoderma lucidum
Authors: Shangguan Jiaolei , Qiao Jinjin , Liu He , Zhu Lei , Han Xiaofei , Shi Liang , Zhu Jing , Liu Rui , Ren Ang , Zhao Mingwen 
Published: April 2024

AbstractCellulose is an important abundant renewable resource on Earth, and the microbial cellulose utilization mechanism has attracted extensive attention. Recently, some signalling molecules have been found to regulate cellulose utilization and the discovery of underlying signals has recently attracted extensive attention. In this paper, we found that the hydrogen sulfide (H2S) concentration under cellulose culture condition increased to approximately 2.3-fold compared with that under glucose culture condition in Ganoderma lucidum. Further evidence shown that cellulase activities of G. lucidum were improved by 18.2-27.6% through increasing H2S concentration. Then, we observed that the carbon repressor CreA inhibited H2S biosynthesis in G. lucidum by binding to the promoter of cbs, a key gene for H2S biosynthesis, at “CTGGGG”. In our study, we reported for the first time that H2S increased the cellulose utilization in G. lucidum, and analyzed the mechanism of H2S biosynthesis induced by cellulose. This study not only enriches the understanding of the microbial cellulose utilization mechanism but also provides a reference for the analysis of the physiological function of H2S signals.
Unleashing the power of directed electron transfer: unraveling the potential of {PV4}2 in heterogeneous photocatalysis
Authors: Su Xin , He Yuzan , Li Kunhong , Wang Miao , Tang Wei , Zhang Shihao , Ma Pengtao , Niu Jingyang , Wang Jingping 
Published: April 2024

{PV4}2 unleash the power of directed electron transfer in heterogeneous photocatalysis reduction.
Radiative-convective models of the atmospheres of Uranus and Neptune: Heating sources and seasonal effects
Authors: Milcareck Gwenaël , Guerlet Sandrine , Montmessin Franck , Spiga Aymeric , Leconte Jérémy , Millour Ehouarn , Clément Noé , Fletcher Leigh N. , Roman Michael T. , Lellouch Emmanuel , Moreno Raphaël , Cavalié Thibault , Carrión-González Óscar 
Published: April 2024

Context. The observations made during the Voyager 2 flyby have shown that the stratosphere of Uranus and that of Neptune are warmer than expected by previous models. In addition, no seasonal variability of the thermal structure has been observed on Uranus since Voyager 2 era and significant subseasonal variations have been revealed on Neptune.
Aims. In this paper, we evaluate different realistic heat sources that can induce sufficient heating to warm the atmosphere of these planets and we estimate the seasonal effects on the thermal structure.
Methods. The seasonal radiative-convective model developed by the Laboratoire de Météorologie Dynamique was used to reproduce the thermal structure of these planets. Three hypotheses for the heating sources were explored separately: aerosol layers, a higher methane mole fraction, and thermospheric conduction.
Results. Our modelling indicates that aerosols with plausible scattering properties can produce the requisite heating for Uranus, but not for Neptune. Alternatively, greater stratospheric methane abundances can provide the missing heating on both planets, but the large values needed are inconsistent with current observational constraints. In contrast, adding thermospheric conduction cannot warm the stratosphere of both planets alone. The combination of these heat sources is also investigated. In the upper troposphere of both planets, the meridional thermal structures produced by our model are found inconsistent with those retrieved from Voyager 2/IRIS data. Furthermore, our models predict seasonal variations should exist within the stratospheres of both planets while observations showed that Uranus seems to be invariant to meridional contrasts and only subseasonal temperature trends are visible on Neptune. However, a warm south pole is seen in our simulations of Neptune as observed since 2003.
J0526+5934: A peculiar ultra-short-period double white dwarf
Authors: Rebassa-Mansergas Alberto , Hollands Mark , Parsons Steven G. , Althaus Leandro G. , Pelisoli Ingrid , Irawati Puji , Raddi Roberto , Camisassa Maria E. , Torres Santiago 
Published: April 2024

Context.Ultra-short-period compact binaries are important sources of gravitational waves. The class of short-period compact binaries includes, for example, the progenitors of type Ia supernovae and the progenitors of merger episodes that may lead to massive and magnetic single white dwarfs. J0526+5934 is one such example: it is an unresolved compact binary star with an orbital period of 20.5 min.Aims.The visible component of J0526+5934 was recently claimed to be a hot sub-dwarf star with a CO white dwarf companion. Our aim is to provide strong observational and theoretical evidence that the primary star is instead an extremely low-mass white dwarf, although the hot sub-dwarf nature cannot be completely ruled out.Methods.We analysed optical spectra together with time-series photometry of the visible component of J0526+5934 to constrain its orbital and stellar parameters. We also employed evolutionary sequences for low-mass white dwarfs to derive independent values of the primary mass.Results.From the analysis of our observational data, we find a stellar mass for the primary star in J0526+5934 of 0.26 ± 0.05M⊙, which perfectly matches the 0.237 ± 0.035M⊙independent measurement we derive from the theoretical evolutionary models. This value is considerably lower than the theoretically expected and generally observed mass range for hot sub-dwarf stars, but falls well within the mass limit values of extremely low-mass white dwarfs.Conclusions.We conclude J0526+5934 is the sixth ultra-short-period detached double white dwarf currently known.
L’agroécologie, un cadre pertinent pour penser l’évolution de nos systèmes agricoles et alimentaires
Authors: Ducos Alain , Brun Hugo , Candau Olivia , Deiber Maëlle , Florsheimer Léa , Larribeau Léa , Portet-Tixidor Baptiste 
Published: April 2024

L’agroécologie est un concept dynamique, dont le périmètre et les définitions ont évolué au cours du temps. Dans son acception la plus récente, l’agroécologie se définit comme « l’écologie des systèmes alimentaires durables ». Elle vise à promouvoir des systèmes viables, respectueux des animaux, des humains et de leur environnement, à les transformer en s’attaquant aux causes profondes des problèmes et en apportant des solutions globales et de long terme fondées sur la co-création de connaissances, le partage et l’innovation. Elle est à la fois une science, un ensemble de pratiques et un mouvement social, ces trois éléments étant indispensables pour créer la dynamique nécessaire à la transformation des systèmes. La transition agroécologique mobilise un ensemble de principes. Treize ont été définis à l’échelle des systèmes alimentaires globalement. Un sous-ensemble de ces principes peut être mis en œuvre pour penser l’évolution des systèmes d’élevage spécifiquement : 1) réaliser une gestion intégrée de la santé animale ; 2) potentialiser l’utilisation des ressources naturelles et des coproduits pour diminuer les intrants nécessaires à la production ; 3) optimiser le fonctionnement métabolique des systèmes et réduire les pollutions ; 4) gérer la diversité des ressources et la complémentarité des animaux pour renforcer la résilience des systèmes d’élevage ; 5) adapter les pratiques d’élevage de manière à préserver la biodiversité et à assurer les services écosystémiques associés.
The value of AI-based analysis of fractional flow reserve of volume computed tomographically detected coronary artery stenosis with regard to their hemodynamic relevance
Authors: Noblé Hans-Jürgen , Mühlbauer Nadine , Ehling Josef , Bansmann Paul Martin 
Published: April 2024

Purpose The aim of our work was to demonstrate the importance of artificial intelligence-based analysis of fractional flow reserves of computed tomographically detected coronary artery stenosis with regard to their hemodynamic relevance in patients with unclear chest pain and suspected stable coronary heart disease with a low to medium pre-test probability.
Material and Methods The collective of our retrospective analysis includes 63 patients in whom coronary artery stenosis was detected by volume computed tomographic examination in “one beat, whole heart” mode in the period from March to October 2022. In these patients, the fractional flow reserve was also determined by computed tomography, which was modulated by the use of artificial intelligence.
Results The calculated values of the fractional flow reserve and the degrees of stenosis determined by computed tomography showed a moderate and significant negative correlation for all three coronary vascular territories (LAD/CX/RCA) (correlation coefficient rho = 0.54/0.54/0.6; p < 0.01 respectively). In just over a third (37.6 %) of all stenoses classified as high-grade by computed tomography, the assessment of hemodynamic relevance by calculating the fractional flow reserve deviated from the severity of the stenosis diagnosed by computed tomography, while the results in the peripheral areas “no stenosis/vascular occlusion” were 100 % consistent in each case.
Conclusion The present results of this work illustrate that the calculation of the fractional flow reserve based on artificial intelligence as a supplement to volume computed tomography of the heart can make a decisive contribution to further therapy planning by increasing the specificity of the purely morphological method by the physiological aspect.
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