bluuebunny/crossref_metadata_2025_split huggingface dataset:
Evaluation of thermal shock therapy for reducing pain during intense pulsed light therapy: An intrapatient randomized controlled study
Authors: Zhang Yuanwen , Lu Chuncheng , Yao Zhihui , Chen Yongxin , Luo Shilan 
Published: March 2024

AbstractBackgroundIntense pulsed light (IPL) is used for the treatment and improvement of various skin issues. However, patients often experience local skin burning and pain after IPL treatment. Cooling and analgesic measures are indispensable.AimsTo investigate the clinical effect of thermal shock therapy on pain relief and reduction of adverse reactions during IPL therapy.Patients/MethodsA total of 60 female patients with facial photoaging who received IPL therapy were enrolled in the study. As a comparative split‐face study, one side of the face was randomly selected as the control side. The other side was given thermal shock therapy before and after the IPL treatment immediately as analgesic side. The visual analog scale (VAS) was used to evaluate the pain degree of the patients. The telephone follow‐ups regarding the occurrence of adverse reactions were conducted respectively on the 2nd day, 7th day, and 1 month after treatment.ResultsThe VAS score and skin temperature of analgesia side was lower than that of control side at different stages of treatment. In terms of adverse reactions, the incidence of transient facial redness on the analgesic side was lower than that on the control side. Two patients showed slight secondary pigmentation on the control side, and the other patients showed no other adverse reactions on both sides.ConclusionsThermal shock therapy assisted IPL therapy can reduce skin temperature during treatment, effectively relieve patients' pain, reduce the occurrence of adverse reactions caused by heat injury, and improve patients' comfort level.
Weak evidence of provenance effects in spring phenology across Europe and North America
Authors: Zeng Ziyun Alina , Wolkovich E. M. 
Published: March 2024

Summary

Forecasting the biological impacts of climate change requires understanding how species respond to warmer temperatures through interannual flexible variation vs through adaptation to local conditions. Yet, we often lack this information entirely or find conflicting evidence across studies, which is the case for spring phenology.

We synthesized common garden studies across Europe and North America that reported spring event dates for a mix of angiosperm and gymnosperm tree species in the northern hemisphere, capturing data from 384 North American and 101 European provenances (i.e. populations) with observations from 1962 to 2019, alongside autumn event data when provided.

Across continents, we found no evidence of provenance effects in spring phenology, but strong clines with latitude and mean annual temperature in autumn. These effects, however, appeared to diverge by continent and species type (gymnosperm vs angiosperm), with particularly pronounced clines in North America in autumn events.

Our results suggest flexible, likely plastic responses, in spring phenology with warming, and potential limits – at least in the short term – due to provenance effects for autumn phenology. They also highlight that, after over 250 yr of common garden studies on tree phenology, we still lack a holistic predictive model of clines across species and phenological events.
Dissection of rhizosphere microbiome and exploiting strategies for sustainable agriculture
Authors: Xun Weibing , Liu Yunpeng , Ma Aiyuan , Yan He , Miao Youzhi , Shao Jiahui , Zhang Nan , Xu Zhihui , Shen Qirong , Zhang Ruifu 
Published: March 2024

SummaryThe rhizosphere microbiome plays critical roles in plant growth and provides promising solutions for sustainable agriculture. While the rhizosphere microbiome frequently fluctuates with the soil environment, recent studies have demonstrated that a small proportion of the microbiome is consistently assembled in the rhizosphere of a specific plant genotype regardless of the soil condition, which is determined by host genetics. Based on these breakthroughs, which involved exploiting the plant‐beneficial function of the rhizosphere microbiome, we propose to divide the rhizosphere microbiome into environment‐dominated and plant genetic‐dominated components based on their different assembly mechanisms. Subsequently, two strategies to explore the different rhizosphere microbiome components for agricultural production are suggested, that is, the precise management of the environment‐dominated rhizosphere microbiome by agronomic practices, and the elucidation of the plant genetic basis of the plant genetic‐dominated rhizosphere microbiome for breeding microbiome‐assisted crop varieties. We finally present the major challenges that need to be overcome to implement strategies for modulating these two components of the rhizosphere microbiome.
Dreaming of Cydalise: Chimeras, disfiguration, translation
Authors: Luca Dinu 
Published: March 2024

AbstractThis essay argues that translation, next to other kinds of language ferrying, can be profitably seen as remedial work. To make this point, I discuss five attempts at poetising ‘Cydalise’, a chimera dreamed into being by Théophile Gautier (1811–1872). After introducing it, I investigate three of Gautier's failed textualisations of this chimera and the resulting early tokens of literary chinoiserie and literary pastel. I then explore the disfigurations Cydalise suffers at the hands of Romanian writer Vasile Alecsandri (1821–1890) as he appropriates, refashions and explodes chinoiserie (and distorts pastel) in his endeavour to capture Gautier's ‘dream in its reality’. I next trace the translatorial moves Chinese poet Shao Xunmei (1906–1968) enacts finally to transport Cydalise into text, as he also pays discreet homage to the powers of translation. I conclude by giving firmer contours to the hypertextual landscape I imagine, which equally welcomes originals, translations and everything in between.
The operation of PEPCK increases light harvesting plasticity in C4 NAD–ME and NADP–ME photosynthetic subtypes: A theoretical study
Authors: Bellasio Chandra , Lundgren Marjorie R. 
Published: March 2024

AbstractThe repeated emergence of NADP–malic enzyme (ME), NAD–ME and phosphoenolpyruvate carboxykinase (PEPCK) subtypes of C4 photosynthesis are iconic examples of convergent evolution, which suggests that these biochemistries do not randomly assemble, but are instead specific adaptations resulting from unknown evolutionary drivers. Theoretical studies that are based on the classic biochemical understanding have repeatedly proposed light‐use efficiency as a possible benefit of the PEPCK subtype. However, quantum yield measurements do not support this idea. We explore this inconsistency here via an analytical model that features explicit descriptions across a seamless gradient between C4 biochemistries to analyse light harvesting and dark photosynthetic metabolism. Our simulations show that the NADP–ME subtype, operated by the most productive crops, is the most efficient. The NAD–ME subtype has lower efficiency, but has greater light harvesting plasticity (the capacity to assimilate CO2 in the broadest combination of light intensity and spectral qualities). In both NADP–ME and NAD–ME backgrounds, increasing PEPCK activity corresponds to greater light harvesting plasticity but likely imposed a reduction in photosynthetic efficiency. We draw the first mechanistic links between light harvesting and C4 subtypes, providing the theoretical basis for future investigation.
Defence and nutrition synergistically contribute to the distinct tolerance of rice subspecies to the stem borer, Chilo suppressalis
Authors: Ju Jia‐Fei , Yang Lei , Shen Chen , Li Jian‐Cai , Hoffmann Ary A. , Huang Yu‐Xuan , Zhu Feng , Ji Rui , Luo Guang‐Hua , Fang Ji‐Chao 
Published: March 2024

AbstractDamage caused by the rice striped stem borer (SSB), Chilo suppressalis (Walker) (Lepidoptera: Pyralidae), is much more severe on indica/xian rice than on japonica/geng rice (Oryza sativa) which matches pest outbreak data in cropping regions of China. The mechanistic basis of this difference among rice subspecies remains unclear. Using transcriptomic, metabolomic and genetic analyses in combination with insect bioassay experiments, we showed that japonica and indica rice utilise different defence responses to repel SSB, and that SSB exploited plant nutrition deficiencies in different ways in the subspecies. The more resistant japonica rice induced patterns of accumulation of methyl jasmonate (MeJA—part of a defensive pathway) and vitamin B1 (VB1—a nutrition pathway) distinct from indica cultivars. Using gene‐edited rice plants and SSB bioassays, we found that MeJA and VB1 jointly affected the performance of SSB by disrupting juvenile hormone levels. In addition, genetic variants of key biosynthesis genes in the MeJA and VB1 pathways (OsJMT and OsTH1, respectively) differed between japonica and indica rice and contributed to performance differences; in indica rice, SSB avoided the MeJA defence pathway and hijacked the VB1 nutrition‐related pathway to promote development. The findings highlight important genetic and mechanistic differences between rice subspecies affecting SSB damage which could be exploited in plant breeding for resistance.
Transcendental philosophy and logic diagrams
Authors: Lemanski Jens 
Published: March 2024

AbstractLogic diagrams have seen a resurgence in their application in a range of fields, including logic, biology, media science, computer science and philosophy. Consequently, understanding the history and philosophy of these diagrams has become crucial. As many current diagrammatic systems in logic are based on ideas that originated in the 18th and 19th centuries, it is important to consider what motivated the use of logic diagrams in the past and whether these reasons are still valid today. This paper proposes that transcendental philosophy was a key inspiration for the development of logic diagrams and that such diagrams can be employed in transcendental arguments, even after the linguistic turn.
Impact of translational regulation on diel expression revealed by time‐series ribosome profiling in Arabidopsis
Authors: Aoyama Haruka , Arae Toshihiro , Yamashita Yui , Toyoda Atsushi , Naito Satoshi , Sotta Naoyuki , Chiba Yukako 
Published: March 2024

SUMMARYPlants have developed the ability to adjust to the day/night cycle through the expression of diel genes, which allow them to effectively respond to environmental changes and optimise their growth and development. Diel oscillations also have substantial implications in many physiological processes, including photosynthesis, floral development, and environmental stress responses. The expression of diel genes is regulated by a combination of the circadian clock and responses to environmental cues, such as light and temperature. A great deal of information is available on the transcriptional regulation of diel gene expression. However, the extent to which translational regulation is involved in controlling diel changes in expression is not yet clear. To investigate the impact of translational regulation on diel expression, we conducted Ribo‐seq and RNA‐seq analyses on a time‐series sample of Arabidopsis shoots cultivated under a 12 h light/dark cycle. Our results showed that translational regulation is involved in about 71% of the genes exhibiting diel changes in mRNA abundance or translational activity, including clock genes, many of which are subject to both translational and transcriptional control. They also revealed that the diel expression of glycosylation and ion‐transporter‐related genes is mainly established through translational regulation. The expression of several diel genes likely subject to translational regulation through upstream open‐reading frames was also determined.
Development and application of a bioassay for assessing the dissipation rate of the synthetic strigolactone GR24 in soil
Authors: Wallach Amit , Matzrafi Maor , Distelfeld Assaf , Nasser Ahmed , Eizenberg Hanan 
Published: March 2024

AbstractRoot parasitic weeds of the genera Striga, Orobanche, and Phelipanche cause enormous economic losses for farmers the world over. Germination of the seeds of these species requires a chemotropic signal in the form of strigolactones in the soil. Once a root parasitic weed germinates and becomes established, it draws nutrition from the host plants, leading to plant death and hence yield reduction. Despite the obvious importance of strigolactones, there is currently almost no information about the fate of strigolactones in the soil, although microbial involvement has been suggested. To begin to address this knowledge lacuna, we developed a bioassay—using the strigolactone synthetic analogue GR24—as a high‐throughput, inexpensive, and compact tool for monitoring the dissipation of strigolactones (GR24 in this case) in the soil by microorganisms and/or environmental conditions, including GR24 concentration, soil type, and temperature. As part of the bioassay, it was found that autoclaving the soil delayed the dissipation of GR24 versus sterilisation by gamma radiation and or no sterilisation. Analytical LC–MS/MS with a detection limit of 0.1 ppb confirmed this finding, with no GR24 being detected in non‐sterilised soil after 24 h. Application of the bioassay to monitor GR24 dissipation in soil showed that the higher the GR24 concentration the slower the degradation, and the higher the temperature, the faster the degradation. It also showed that the organic matter content of the soil affected the GR24 dissipation rate. These findings were also confirmed by analytical LC–MS/MS, indicating the applicability of the methodology for studies of root exudes.
Composite Structural Battery: A Review
Authors: Mao Rui , Lei Zhenkun , Di Jianyu , Shang Yuxiang , Bai Ruixiang , Yan Cheng 
Published: March 2024

Abstract
Energy storage is a common challenge for spacecraft and vehicles, whose operating range and operational availability are limited to a considerable extent by the storage capacity; mass and volume are the main issues. Composite structural batteries (CSBs) are emerging as a new solution to reduce the size of electric systems that can bear loads and store energy. Carbon-fiber-reinforced polymers (CFRP) offer significant advantages over metallic structures. This paper reviews the recent design of multifunctional composites by combining batteries with CFRP to obtain structural lightweight and excellent mechanical properties. The assembly methods for different CSBs based on the type of electrolyte used are discussed. A comparative analysis is performed on the energy density, rate performance, cycle performance, and mechanical performance with a particular focus on the multifunctional efficiency of various CSBs. Furthermore, the opportunities and challenges in CSBs are discussed, and research ideas are proposed for this emerging field.
Simplified Formulation for Bush, Gibson, and Thomas Model
Authors: Xu Yang , Wu Shuo , Jackson Robert L. 
Published: March 2024

Abstract
The random process model, also known as the multi-asperity contact model or statistical model, is one of the dominant methodologies for analyzing the contact between nominally flat rough surfaces. In 1975, Bush, Gibson, and Thomas developed a complete random process model (known as the BGT model) assuming that solid–solid contacts occur on the summits of the asperities, which are semi-ellipsoids uniquely described by three random variables (the asperity height and two principal peak curvatures). The Hertzian elliptic contact theory states that the contact area and normal load are implicit functions of the random variables, which results in an original BGT model with a complex formulation. In this study, we used an adapted Hertzian elliptic contact theory to simplify the formulation of the BGT model. The relative contact area to normal load relation predicted by the simplified BGT model perfectly agrees with that of the original formulation. It is anticipated that rough surface contact models with complex asperity interactions can be effectively built under the framework of this simplified BGT model.
Th1 cell immune response in
Talaromyces marneffei
infection with anti-interferon-γ autoantibody syndrome
Authors: Qiu Ye , Li Zheng-Tu , Zeng Wen , Yang Jing-Lu , Tang Meng-Xin , Wang Yan , Wang Hao-Ru , Li Yuanxiang , Zhan Yang-Qing , Li Shao-Qiang , Zhang Jian-Quan , Ye Feng 
Published: March 2024

ABSTRACT

Anti-interferon-γ autoantibody (AIGA) syndrome may be the basis of disseminated
Talaromyces marneffei
infection in human immunodeficiency virus (HIV)-negative adults. However, the pathogenesis of Th1 cell immunity in
T. marneffei
infection with AIGA syndrome is unknown. A multicenter study of HIV-negative individuals with
T. marneffei
infection was conducted between September 2018 and September 2020 in Guangdong and Guangxi, China. Patients were divided into AIGA-positive (AP) and AIGA-negative (AN) groups according to the AIGA titer and neutralizing activity. The relationship between AIGA syndrome and Th1 immune deficiency was investigated by using AP patient serum and purification of AIGA. Fifty-five HIV-negative adults with disseminated
T. marneffei
infection who were otherwise healthy were included. The prevalence of AIGA positivity was 83.6%. Based on their AIGA status, 46 and 9 patients were assigned to the AP and AN groups, respectively. The levels of Th1 cells, IFN-γ, and T-bet were higher in
T. marneffei
-infected patients than in healthy controls. However, the levels of CD4
+
T-cell STAT-1 phosphorylation (pSTAT1) and Th1 cells were lower in the AP group than in the AN group. Both the serum of patients with AIGA syndrome and the AIGA purified from the serum of patients with AIGA syndrome could reduce CD4
+
T-cell pSTAT1, Th1 cell differentiation and T-bet mRNA, and protein expression. The Th1 cell immune response plays a pivotal role in defense against
T. marneffei
infection in HIV-negative patients. Inhibition of the Th1 cell immune response may be an important pathological effect of AIGA syndrome.

IMPORTANCE

The pathogenesis of Th1 cell immunity in
Talaromyces marneffei
infection with anti-interferon-γ autoantibody (AIGA) syndrome is unknown. This is an interesting study addressing an important knowledge gap regarding the pathogenesis of
T. marneffei
in non-HIV positive patients; in particular patients with AIGA. The finding of the Th1 cell immune response plays a pivotal role in defense against
T. marneffei
infection in HIV-negative patients, and inhibition of the Th1 cell immune response may be an important pathological effect of AIGA syndrome, which presented in this research could help bridge the current knowledge gap.
Acute spontaneous vortex vein occlusion: clinical features, multimodal imaging and natural course
Authors: Xue Kang , Meng Fengxi , Ren Hui , Yue Han , He Lin Jonathan , Ma Ruiqi , Lin Xintong , Qian Jiang , Guo Jie 
Published: March 2024

Aims
To describe the clinical features, multimodal imaging, treatments and natural course of acute spontaneous vortex vein occlusion.

Methods
Clinical data were collected on nine patients with acute vortex vein occlusion. The symptoms and signs, multimodal imaging, treatments and follow-up results were summarised.

Results
Six patients (66.7%) were men and three (33.3%) were women. The mean age was 47.8±15.4 years. Patients were initially misdiagnosed as having choroidal tumour (66.7%), scleritis (22.2%) and peripheral exudative haemorrhagic chorioretinopathy (11.1%). The related clinical characteristics included choroidal pseudo-tumour (100%), anterior segment injection (88.9%), acute ocular pain (77.8%), transient blurred vision (66.7%) and subsequent scleral icterus (66.7%). Six patients (66.7%) experienced a definite Valsalva manoeuvre prior to the onset. In acute phase, ultrasonography showed a low-to-medium reflective lesion without inside blood flow signal (mean thickness, 2.7±0.6 mm). Swept-source optical coherence tomography angiography (SS-OCTA) demonstrated the dilated vortex veins and ampulla with suprachoroidal haemorrhage and exudation. Indocyanine green angiography (ICGA) demonstrated choroidal circulation abnormalities in the affected quadrant. MRI showed a well-defined mass with enhancement. The main treatment was medical observation (44.5%). The choroidal pseudo-tumour spontaneously resolved with a mean course of 4.1±1.9 weeks.

Conclusions
Acute vortex vein occlusion is a rare condition and initial misdiagnosis is not uncommon. It is mainly identified as an evanescent choroidal pseudo-tumour with acute pain, red eye and blurred vision. Widefield ICGA and SS-OCTA can offer valuable diagnostic clues. Medical observation may be a treatment option.
Efficacy of a new injury prevention programme (FUNBALL) in young male football (soccer) players: a cluster-randomised controlled trial
Authors: Obërtinca Rilind , Meha Rina , Hoxha Ilir , Shabani Bujar , Meyer Tim , aus der Fünten Karen 
Published: March 2024

ObjectivesTo evaluate the efficacy of a new multicomponent, exercise-based injury prevention programme in football players 13–19 years old.MethodsTwo-arm cluster-randomised controlled trial with clubs as the unit of randomisation. 55 football teams from Kosovo of the under 15, under 17 and under 19 age groups were randomly assigned to the intervention (INT; 28 teams) or the control group (CON; 27 teams) and were followed for one football season (August 2021–May 2022). The INT group performed the ‘FUNBALL’ programme after their usual warm-up at least twice per week, while the CON group followed their usual training routine. The primary outcome measure was the overall number of football-related injuries. Secondary outcomes were region-specific injuries of the lower limbs (hip/groin, thigh, knee, lower leg, ankle and foot) and injury severity.Results319 injuries occurred, 132 in the INT and 187 in the CON group. The INT group used the ‘FUNBALL’ programme in 72.2% of all training sessions, on average 2.2 times per week. There was a significantly lower incidence in the INT group regarding the overall number of injuries (incidence rate ratio (IRR) 0.69, 95% CI 0.55 to 0.87), the number of thigh injuries (IRR 0.62, 95% CI 0.39 to 0.98), of moderate (time loss between 7 and 28 days) (IRR 0.65, 95% CI 0.44 to 0.97) and of severe injuries (time loss >28 days) (IRR 0.51, 95% CI 0.28 to 0.91).ConclusionThe ‘FUNBALL’ programme reduced the incidence of football-related injuries among male adolescent football players, and its regular use for injury prevention in this population is recommended.Trial registration numberNCT05137015.