bluuebunny/crossref_metadata_2025_split huggingface dataset:
Substance use disorders in women with anorexia nervosa
Authors: Root Tammy L. , Pinheiro Andréa Poyastro , Thornton Laura , Strober Michael , Fernandez‐Aranda Fernando , Brandt Harry , Crawford Steve , Fichter Manfred M. , Halmi Katherine A. , Johnson Craig , Kaplan Allan S. , Klump Kelly L. , La Via Maria , Mitchell James , Woodside D. Blake , Rotondo Alessandro , Berrettini Wade H. , Kaye Walter H. , Bulik Cynthia M. 
Published: March 2009

AbstractObjective:We examined prevalence of substance use disorders (SUD) in women with: (1) anorexia nervosa (AN) restricting type (RAN); (2) AN with purging only (PAN); (3) AN with binge eating only (BAN); and (4) lifetime AN and bulimia nervosa (ANBN). Secondary analyses examined SUD related to lifetime purging behavior and lifetime binge eating.Method:Participants (N= 731) were drawn from the International Price Foundation Genetic Studies.Results:The prevalence of SUD differed across AN subtypes, with more in the ANBN group reporting SUD than those in the RAN and PAN groups. Individuals who purged were more likely to report substance use than those who did not purge. Prevalence of SUD differed across lifetime binge eating status.Discussion:SUD are common in AN and are associated with bulimic symptomatology. Results underscore the heterogeneity in AN, highlighting the importance of screening for SUD across AN subtypes. © 2009 by Wiley Periodicals, Inc. Int J Eat Disord 2010
Sexual functioning in women with eating disorders
Authors: Pinheiro Andréa Poyastro , Raney T.J. , Thornton Laura M. , Fichter Manfred M. , Berrettini Wade H. , Goldman David , Halmi Katherine A. , Kaplan Allan S. , Strober Michael , Treasure Janet , Woodside D. Blake , Kaye Walter H. , Bulik Cynthia M. 
Published: March 2009

AbstractObjective:To describe sexual functioning in women with eating disorders.Method:We assessed physical intimacy, libido, sexual anxiety, partner status, and sexual relationships in 242 women from the International Price Foundation Genetic Studies relative to normative data.Results:Intercourse (55.3%), having a partner (52.7%), decreased sexual desire (66.9%), and increased sexual anxiety (59.2%) were common. Women with restricting and purging anorexia nervosa had a higher prevalence of loss of libido than women with bulimia nervosa and eating disorder not otherwise specified (75%, 74.6%, 39%, and 45.4%, respectively). Absence of sexual relationships was associated with lower minimum lifetime body mass index (BMI) and earlier age of onset; loss of libido with lower lifetime BMI, higher interoceptive awareness and trait anxiety; and sexual anxiety with lower lifetime BMI, higher harm avoidance and ineffectiveness. Sexual dysfunction in eating disorders was higher than in the normative sample.Discussion:Sexual dysfunction is common across eating disorders subtypes. Low BMI is associated with loss of libido, sexual anxiety, and avoidance of sexual relationships. © 2009 by Wiley Periodicals, Inc. Int J Eat Disord 2010
Application of the Octacarbonyldicobalt‐Catalyzed Carbonylation of Ethyl Diazoacetate for the One‐Pot Synthesis of N‐tert‐Butyl‐trans‐α‐ethoxycarbonyl‐β‐phenyl‐β‐lactam
Authors: Fördős Eszter , Tuba Róbert , Párkányi László , Kégl Tamás , Ungváry Ferenc 
Published: March 2009

AbstractN‐tert‐Butyl‐trans‐α‐ethoxycarbonyl‐β‐phenyl‐β‐lactam has been prepared in 95 % yield (GC) by the octacarbonyldicobalt‐catalyzed carbonylation of ethyl diazoacetate in dichloromethane in the presence of N‐tert‐butylbenzaldimine at 10 °C and 75 bar pressure of carbon monoxide. The key step of the reaction is the catalytic formation of the highly reactive (ethoxycarbonyl)ketene from both of the intermediary complexes [Co2(CO)7(CHCO2Et)] and [Co2(CO)6(CHCO2Et)2], which is in situ scavenged by the imine in a [2+2] cycloaddition reaction. DFT (PBEPBE/6‐31G**) calculations revealed that the reaction follows a two‐step mechanism via a noncyclic intermediate with a reaction free energy of –15.9 kcal/mol and a free‐energy barrier of 24.7 kcal/mol for the second rate‐limiting step. The computation also shows that the formation of the trans isomer is preferred both kinetically and thermodynamically. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2009)
Fe(CN)64−‐Doped‐Glutaraldehyde‐Cross‐Linked Poly‐L‐Lysine Film Electrode. Part 2: Stability Improvement and Selective Detection of Dopamine in the Presence of Ascorbic Acid
Authors: Thangamuthu R. , Wu Yu‐Ching , Chen Shen‐Ming 
Published: March 2009

AbstractHighly stable Nafion‐covered hexacyanoferrate‐doped‐glutaraldehyde‐cross‐linked poly‐L‐lysine (PLL‐GA‐Fe(CN)64−/Naf) film modified glassy carbon electrode (GCE), for the selective detection of dopamine (DA) in the presence of ascorbic acid (AA), was prepared by first ion‐exchanging Fe(CN)64− into PLL‐GA coating on GCE then sealing it with a Nafion outer layer. The Nafion over layer is crucial in preventing leaching of Fe(CN)64− ions from the inner layer. The first layer was acting as electrocatalyst for DA oxidation and the outer coating acted as discriminating layer for selective permeation of DA in the presence of interfering anionic species. More than 90% of the initial response was retained after coating with the Nafion protecting layer compared to a huge loss (>60%) without Nafion outer layer. 5% Nafion coating was identified as optimum thickness for the selective detection of DA in the presence of AA.
Efficient Synthesis of a New Podand and Application as a Suitable Carrier for Silver Ion‐Selective Electrode
Authors: Mashhadizadeh Mohammad Hossein , Shockravi Abbas , Khoubi Zakiyeh , Heidarian Davood 
Published: March 2009

AbstractA new podand of 1,1′‐thia‐bis‐[1‐(chloroethan‐2‐acetamid‐α‐oxy)] naphtol was synthesized and used as a suitable carrier for Ag+ PVC membrane electrode. The electrode exhibited linear response with a Nernstian slope of (59.5±0.8 mV/decade) within a wide concentration range of 1.0×10−7 to 1.5×10−2 mol L−1 silver ions. The electrode had a fast response time of <10 s and detection limit of 8.6×10−8 mol L−1 with a working pH range from 3.7 to 9.0. The electrode was highly selective for Ag(I) ions over a large number of cations such as alkali, alkaline earth, and heavy metal ions. The proposed sensor has been applied as an indicator electrode for indirect determination of vitamin B1 in tablets by determination of Cl− ions in this compound with a standard solution of Ag(NO3).
Evaluation of Peakmaster for computer‐aided multivariate optimisation of a CE separation of 17 antipsychotic drugs using minimal experimental data
Authors: Johns Kara F. , Breadmore Michael C. , Bruno Raimondo , Haddad Paul R. 
Published: March 2009

AbstractThe computer‐assisted development of a CE method for compliance monitoring of a group of 17 antipsychotic drugs (chlorpromazine hydrochloride, clozapine, droperidol, flupenthixol dihydrochloride, fluphenazine dihydrochloride, haloperidol, pimozide, thioridazine hydrochloride, trifluoperazine dihydrochloride, prochlorperazine dimaleate, amisulpride, aripiprazole, olanzapine, quetiapine fumarate, risperidone, ziprasidone, and zuclopenthixol dihydrochloride) was performed. Peakmaster, a free simulation program for CE, was employed in a multivariate optimisation approach to determine suitable BGE conditions with minimal experimentation. However, analyte input parameters (pKaand limiting ionic mobility) were not included within the software and required determination. Limiting ionic mobility was determined experimentally, while pKavalues were calculated using ACD Labs™ software. A modified chromatographic response factor, which identified the BGE providing the greatest resolution between each pair of peaks within 10 min, was used and determined a pH 2.5 and an ionic strength of 50 mM as optimal. Marked disparities were apparent between experimentally determined and computer‐simulated results, due to error associated with pKavalues calculated using ACD Labs™. These results confirm that Peakmaster analyses are highly sensitive to pKavalues, especially where the pH of the BGE is in the proximity of the analyte pKa; but also that Peakmaster does allows a rational approach to dramatically reduce the amount of experimental work required for multivariate optimisation of conditions for CE.
Colloidal particle deposition from electrokinetic flow in a microfluidic channel
Authors: Unni Harikrishnan Narayanan , Yang Chun 
Published: March 2009

AbstractThis study reports a theoretical and experimental study on the irreversible deposition of colloidal particles from electrokinetic microfluidic flow. The electrokinetic particle transport model presented in this study is based on the stochastic Langevin equation, incorporating the electrical, hydrodynamic, Derjaguin–‐Landau–Verwey–Overbeek colloidal interactions and random Brownian motion of colloidal particles. Brownian dynamics simulation is used to compute the particle deposition in terms of the surface coverage. Direct videomicroscopic observation using the parallel‐plate flow cell technique is employed to determine the deposition kinetics of polystyrene latex particles in NaCl electrolytes. The theoretical predictions are compared with experimental results, and a reasonable agreement is found.
Dispersion of protein bands in a horseshoe microchannel during IEF
Authors: Shim Jaesool , Dutta Prashanta , Ivory Cornelius F. 
Published: March 2009

AbstractAmpholyte‐based IEF is simulated for a 2‐D horseshoe microchannel. The IEF model takes into account ionic‐strength‐dependent mobility corrections for both proteins and ampholytes. The Debye–Huckel–Henry model is employed to correct the protein mobilities and the Onsager–Debye–Huckel model is used to obtain effective mobilities of ampholytes from their limiting mobility. IEF simulations are conducted in the presence of 25 ampholytes (ΔpK=3.0) within a pH range of 6–9 under an electric field of 300 V/cm and using four proteins (pIs=6.49, 7.1, 7.93 and 8.6) focused in a 1‐cm‐long microchannel. The numerical results show that the concentrations of proteins and ampholytes are different when mobility corrections are considered but that the focusing positions remain the same regardless of mobility corrections. Our results also demonstrate that, unlike linear electrophoresis in which the bands deform significantly as they traverse a bend, during the transient portion of IEF racecourse dispersion is mitigated by focusing and, at focused‐state, those bands that focus in the bend show no radial concentration dependence, i.e. they completely recover from racecourse dispersion, even within a tight turn.
A generalization of the Barone‐Adesi and Whaley approach for the analytic approximation of American options
Authors: Guo Jia‐Hau , Hung Mao‐Wei , So Leh‐Chyan 
Published: March 2009

AbstractThis article introduces a general quadratic approximation scheme for pricing American options based on stochastic volatility and double jump processes. This quadratic approximation scheme is a generalization of the Barone‐Adesi and Whaley approach and nests several option models. Numerical results show that this quadratic approximation scheme is efficient and useful in pricing American options. © 2009 Wiley Periodicals, Inc. Jrl Fut Mark 29:478–493, 2009
A new scheme for static hedging of European derivatives under stochastic volatility models
Authors: Takahashi Akihiko , Yamazaki Akira 
Published: March 2009

AbstractThis study proposes a new scheme for static hedging of European path‐independent derivatives under stochastic volatility models. First, we show that pricing European path‐independent derivatives under stochastic volatility models is transformed to pricing those under one‐factor local volatility models. Next, applying an efficient static replication method for one‐dimensional price processes developed by Takahashi and Yamazaki (2008), we present a static hedging scheme for European path‐independent derivatives. Finally, a numerical example comparing our method with a dynamic hedging method under Heston's (1993) stochastic volatility model is used to demonstrate that our hedging scheme is effective in practice. © 2009 Wiley Periodicals, Inc. Jrl Fut Mark 29:397–413, 2009
Do investors learn about analyst accuracy? A study of the oil futures market
Authors: Chang Charles , Daouk Hazem , Wang Albert 
Published: March 2009

AbstractWe study the impact of analyst forecasts on prices to determine whether investors learn about analyst accuracy. The straight‐forward relationship between supply and price, the economic importance of the market, the predictable timing of forecast error realizations, and the high frequency of the data make the crude oil market an interesting and advantageous setting. We find that prices rise (fall) when analysts forecast a decrease (increase) in supplies. During the 15 minutes following supply announcements, prices rise (fall) when forecasts have been too high (low). Importantly, both relationships are stronger for more accurate analysts, implying that investors learn about analyst accuracy. © 2009 Wiley Peridocals, Inc. Jrl Fut Mark 29:414–429, 2009
Subjective cognitive impairment: increased prefrontal cortex activation compared to controls during an encoding task
Authors: Rodda Joanne E. , Dannhauser Thomas M. , Cutinha Darren J. , Shergill Sukhwinder S. , Walker Zuzana 
Published: March 2009

AbstractObjectiveSubjective cognitive impairment (SCI) has been proposed as a clinical stage which may precede mild cognitive impairment in the clinical continuum of AD, and is characterised by the presence of subjective memory complaints in the absence of objective cognitive deficits. Specific memory‐related brain activation differences have been reported in mild cognitive impairment and in cognitively normal individuals at known genetic risk of AD; our objective was to determine whether similar differences are present in people with SCI.MethodsWe compared brain activation in a memory clinic sample of 10 SCI subjects and 10 controls during a verbal episodic memory encoding task using functional magnetic resonance imaging (fMRI).ResultsThere were no differences between groups on measures of encoding success (recognition accuracy) nor was there evidence of altered semantic processing. Both groups activated left prefrontal cortex (PFC) and cerebellum during encoding. The SCI group also demonstrated activation in left medial temporal, occipitoparietal and medial frontal cortex. Group comparisons revealed increased activation in SCI in left PFC, where activation strength correlated with memory task performance.ConclusionsThe activation differences reported in this study may reflect the employment of compensatory strategies in the face of early AD pathology, although a number of alternative explanations need to be considered. Further studies with larger samples may help to determine whether the observed activation changes are likely to be associated with early neuropathological processes or with other unrelated factors. Copyright © 2009 John Wiley & Sons, Ltd.
Voxel based morphometry features and follow‐up of amnestic patients at high risk for Alzheimer's disease conversion
Authors: Rami Lorena , Gómez‐Anson Beatriz , Monte Gemma C. , Bosch Beatriz , Sánchez‐Valle Raquel , Molinuevo José L. 
Published: March 2009

AbstractObjectiveNeuroimaging techniques are able to mark distinct structural and metabolic changes in patients at risk for Alzheimer's disease (AD). The objectives of the study were to compare regional grey matter density in prodromal Alzheimer's disease (Prd‐AD), amnestic mild cognitive impairment (aMCI), mild AD patients and healthy aged controls, to study prospectively their clinical and neuropsychological evolution and to evaluate the accuracy of proposed Prd‐AD criteria to detect AD conversion.MethodsTwenty‐seven controls, 16 aMCI, 32 Prd‐AD and 34 probable mild AD were included. Evaluations were performed at baseline and annually during a 2‐year prospective follow‐up period. Focal grey matter density loss was calculated through voxel based morphometry analysis at baseline. Sensitivity, specificity, positive and negative predictive values of Prd‐AD criteria were calculated.ResultsPr‐AD, compared to aMCI, had decreased grey matter density mainly in both hippocampi and inferior temporal cortex (p < 0.001). AD patients compared with Prd‐AD, presented grey matter loss in the right posterior and lateral temporal, inferior frontal and parietal cortex and left posterior temporal (p < 0.001). After 2‐year follow‐up, Prd‐AD patients presented higher cognitive decline and conversion rate to AD (83.3%) than aMCI (21.4%; p < 0.0001). The sensitivity of Prd‐AD criteria to predict AD conversion in the group of amnestic patients was 89.3; specificity 68.7; positive predictive value 83.3 and negative predictive value 78.6.ConclusionMagnetic resonance imaging provides evidence of more severe temporal grey matter loss in Prd‐AD group than in a‐MCI. The proposed criteria present good accuracy to predict AD conversion among amnestic patients. Copyright © 2009 John Wiley & Sons, Ltd.
The suitability of the BSRS‐5 for assessing elderly who have attempted suicide and need to be referred for professional mental health consultation in a metropolitan city, Taiwan
Authors: Chen Wei‐Jen , Chen Cheng‐Chung , Ho Chi‐Kung , Lee Ming‐Been , Chung Yi‐Ting , Wang Ying‐Chuan , Lin Guei‐Ging , Lu Ren‐yi , Sun Feng‐Ching , Chou Frank Huang‐Chih 
Published: March 2009

AbstractObjectivesThe goals of this study are to (1) investigate the prevalence of necessary referral for professional mental health consultation for elderly people who attempted suicide (“suicide‐attempted”) in Kaohsiung city, Taiwan during 2006–2007, (2) assess whether the 5‐item Brief Symptom Rating Scale (BSRS‐5) can be used as an efficient screening instrument for assessing the probability of a second suicide attempt among the elderly, and (3) examine predictors of needing referral among the suicide‐attempted.MethodsDuring the study period, 144 suicide‐attempted elderly subjects were enrolled. Demographic data, BSRS‐5, SAD PERSONS scale, and Medical Outcome Study Short Form‐12 (MOS SF‐12) data were collected by a trained semi‐professional. The prevalence of necessary referrals for the suicide‐attempted elderly was estimated, and the salient factors for their referral were evaluated with logistic regression analysis.ResultsA total of 109 participants out of the 144 recruited completed the questionnaires, giving a response rate of 75.7%. The prevalence of necessary referrals for professional mental health consultation was 33.9% (37/109). The significant predictors of needing referrals were lower scores for MCS (OR = 0.89; 95% CI = 0.83–0.96), family discord (OR = 3.86; 95% CI = 1.17–12.75), and type of interviewee (OR = 4.97; 95% CI = 1.57–15.74).ConclusionWhen the BSRS‐5 is used to evaluate the referral of elderly patients who have attempted suicide for a professional mental health consultation, it is best to conduct in‐person interviews to ask whether the elderly patient still has any suicidal ideation. In addition, evaluating quality of life and level of family discord may also be crucial for suicide prevention in the elderly. Copyright © 2009 John Wiley & Sons, Ltd.
The prevalence of disability in the oldest‐old is high and continues to increase with age: findings from The 90+ Study
Authors: Berlau Daniel J. , Corrada María M. , Kawas Claudia 
Published: March 2009

AbstractObjectivesTo examine the prevalence and type of disability in the oldest‐old (90+), the fastest growing age group in the United States.MethodsThe current study included functional data on 697 participants from The 90+ Study, a population‐based longitudinal study of aging and dementia in people aged 90 and older. Data were obtained by participant's informants via a written questionnaire. The prevalence of disability was calculated for two definitions using activities of daily living (ADLs). ADL difficulty was defined as difficulty with one or more ADLs whereas ADL dependency was defined as needing help on one or more ADLs.ResultsADL difficulty was present in 71% in 90–94 year olds, 89% in 95–99 year olds, and 97% in centenarians. ADL dependency was present in 44% of 90–94 year olds, 66% of 95–99 year olds, and 92% of centenarians. The ADL most commonly causing difficulty was walking (70%) whereas the ADL most commonly causing dependency was bathing (51%). Age, gender, and institutionalization were significantly associated with both ADL difficulty and ADL dependency.ConclusionsSimilar to studies in younger individuals, the current study suggests that the prevalence of disability continues to increase rapidly in people aged 90 and older. With the rapid growth in the number of people in this age group, disability in the oldest‐old has major public health implications. Copyright © 2009 John Wiley & Sons, Ltd.
Marginal mandibular nerve injury during neck dissection and its impact on patient perception of appearance
Authors: Batstone Martin D. , Scott Barry , Lowe Derek , Rogers Simon N. 
Published: March 2009

AbstractBackground.Neck dissection to remove cervical lymph nodes is common practice in head and neck cancer management. The marginal mandibular nerve may be injured during neck dissection, particularly of level 1. The rate of injury to this nerve is underreported in the literature and its impact on patients is not well defined.Methods.An observational study was undertaken on patients who had undergone neck dissection over a 5‐year period. The patients were examined for weakness and given a questionnaire related their perception of their appearance and their function.Results.Sixty‐six patients were identified who had undergone 85 neck dissections. The rate of House Brackmann injury was 18% when analyzed by patient and 23% by neck. There were moderate correlations between observed injury and subjective responses to questions relating to ability to smile and weakness of the lower lip.Discussion.The rate of smile asymmetry following neck dissection is relatively high; however, severe injuries to the marginal mandibular nerve are uncommon. © 2009 Wiley Periodicals, Inc. Head Neck, 2009