bluuebunny/crossref_metadata_2025_split huggingface dataset:
Advancing Tennis Analytics: Comprehensive Modeling for Momentum Identification and Strategic Insights
Authors: Lin Junhai , Shao Pengjin , Zhang Qingyang 
Published: March 2024

The 2023 Wimbledon men's singles final featured a thrilling clash between the emerging Spanish talent Carlos Alcaraz and the seasoned Novak Djokovic. Djokovic initially exerted control over the game, but Alcaraz effectively turned the tables and emerged victorious, highlighting the significance of "momentum" in the sport. Despite frequent discussion, effectively quantifying and forecasting the impact of this phenomenon poses significant challenges. Question 1 investigates the methods of tracking the progress of a tennis match and identifying players who demonstrate exceptional performance at specific moments. We constructed a model that considers variables such as serve probability advantage, technical indications, physical fitness, and mental condition. The model use time series analysis to monitor the dynamics of the game. It presents the game progress and player performance through interactive charts, allowing for efficient tracking of shifts in game momentum. Question 2 examines the influence of "momentum" on the game's result. We employed the XGBoost machine learning technique to construct a model, coupled with the particle swarm optimization algorithm to fine-tune parameters, and examined the pivotal aspects that influence the game's momentum. The model's findings demonstrate a notable association between momentum and game performance, which contradicts the belief held by certain coaches that game flow is purely impacted by random events. Question three necessitates the anticipation of significant moments of change in momentum within the game. We developed a predictive model that uses the PSO-XGBoost forest algorithm to accurately forecast the timing of momentum transitions. This is achieved by identifying and analyzing important statistics. The findings demonstrate that the model has the capability to precisely anticipate moments of momentum change, hence offering strategic guidance for coaches and players. Question 4 assessed the adaptability of the model in various competitive settings and produced a suggestion report based on the study of the model's results. We examine the implementation of the concept in several game scenarios and offer coaches and athletes strategic counsel to enhance their readiness and reaction to pivotal occurrences throughout the game. In conclusion, our research offers a comprehensive viewpoint on the significance of momentum in tennis matches and demonstrates the potential of machine learning methods in forecasting and capitalizing on this phenomena. Our approach not only improves comprehension of match progression, but also offers direction on how to implement these observations in actual matches.
Dynamics of Rabies Transmission Model in Human and Dog Populations with Time Delay
Authors: Musa Abdullahi  , Musa Samuel , Hussein Abdulmumini , Song Muhammad I. 
Published: March 2024

Rabies is a fatal zoonotic disease caused by a virus through bites or saliva of an infected animal. Dogs are the main reservoir of Rabies and are responsible for most Human cases worldwide. In this research, a delay differential equations model for assessing the effects of controls and time delay as an incubation period on the transmission dynamics of Rabies in human and dog populations is formulated and analyzed. Basic properties of the model as par theories of delay differential equations are established, and the model is well-posed mathematically and biologically. Analysis of the model shows that there is a locally and globally asymptotically stable rabies-free equilibrium whenever the epidemiological threshold (the control reproduction number,) is less than unity. Furthermore, the model has a unique endemic equilibrium point when the control reproduction number, exceeds unity. Time delay is found to have an influence on the endemicity of rabies. Treatment and Vaccination of humans and dogs, coupled with an annual crop of puppies, are imposed to curtail the spread of Rabies in the populations. Numerical experiments are conducted to illustrate the theoretical results and control strategies.
Delay differential equations, Effective reproduction number, Equilibria, Rabies, Stability
Forecasting of Male Life Expectancy in Nigeria: Box-Jenkins Approach
Authors: Aje Oluranti G. , Akanni Saheed B. , Abdualazeez Ismail A. , Ibrahim Rasheedat A. , Adebayo Azeezat A. O. 
Published: March 2024

Over the past few decades, Males’ life expectancy has been observed to be less than that of females. In the literature, little has been done to forecast the Life expectancy at birth for Males (LEM) in developing countries, especially in Nigeria. To understand the forecasting dynamics of LEM in Nigeria, this work therefore examines the series using the Box-Jenkins (1976) methodology. Pre-examination tests conducted on the series revealed that it is not only a difference stationary process of order one {I(1)} but it is also best fitted by ARIMA (1, 1, 1) model. Moreover, diagnostic checking carried out on the residuals of the fitted model confirmed that the residual is a white noise error term in that it fulfils the assumptions of homoscedasticity, stationarity, and autocorrelation. To obtain a good forecast, the LEM data spanning 1960 to 2014 (55 years) were used to train the model while the remaining LEM data spanning 2015 to 2020 (6 years) were used to test the data. For the test data, the forecasted LEM has been shown to give approximate values of the actual LEM. Findings showed that the LEM is expected to increase slightly by 0.64% within the forecasted periods spanning 2021 to 2030.
Diagnostic checking, Forecasting, Homoscedasticity, Life expectancy, Male, Training sets, Testing sets
PELATIHAN PEMBUATAN KOMPOS BERBAHAN DASAR BATANG DAN KULIT PISANG PADA KELOMPOK WANITA TANI KOPAT II DI DISTRIK PARIWARI KABUPATEN FAKFAK
Authors: Andi Patimang  , Aulia Saraswaty  , Yulianto La Elo  
Published: March 2024

Harga pupuk kimia yang mahal dapat mengakibatkan hasil produksi pertanian tidak optimal. Hal ini dapat diatasi dengan menggunakan pupuk organik berupa kompos yang berbahan baku lokal seperti batang dan kulit pisang. Masalah yang dihadapi adalah mitra belum mengetahui tentang pembuatan kompos batang pisang dan kulit pisang. Kegiatan PKM ini bertujuan untuk menambah ilmu pengetahuan dan keterampilan mengenai cara pembuatan kompos dari batang pisang dan kulit pisang terhadap mitra yaitu kelompok wanita tani Kopat 2. Kegiatan PKM ini dilaksanakan dengan metode pelatihan dan pendampingan. Tahapan kegiatan yang akan dilaksanakan adalah diskusi, persiapan tempat, sarana kegiatan dan persiapan alat dan bahan praktik, pelaksanaan pelatihan (penyuluhan dan praktik) dan pendampingan. Berdasarkan hasil kegiatan dilaksanakan, terlihat respon dan partisipasi dari mitra sangat baik. Mereka beranggapan bahwa dengan adanya pelatihan ini, dapat menambah ilmu pengetahuan dan keterampilan mereka dalam pembuatan kompos batang pisang dan kulit pisang.
Comprehensive analysis of peroxisome proliferator-activated receptors to predict the drug resistance, immune microenvironment, and prognosis in stomach adenocarcinomas
Authors: Jia Qing , Li Baozhen , Wang Xiulian , Ma Yongfen , Li Gaozhong 
Published: March 2024

Background
Peroxisome proliferator-activated receptors (PPARs) exert multiple functions in the initiation and progression of stomach adenocarcinomas (STAD). This study analyzed the relationship between PPARs and the immune status, molecular mutations, and drug therapy in STAD.

Methods
The expression profiles of three PPAR genes (PPARA, PPARD and PPARG) were downloaded from The Cancer Genome Atlas (TCGA) dataset to analyze their expression patterns across pan-cancer. The associations between PPARs and clinicopathologic features, prognosis, tumor microenvironment, genome mutation and drug sensitivity were also explored. Co-expression between two PPAR genes was calculated using Pearson analysis. Regulatory pathways of PPARs were scored using gene set variation analysis (GSVA) package. Quantitative real-time polymerase chain reaction (qRT-PCR), Western blot, Cell Counting Kit-8 (CCK-8) assay and transwell assay were conducted to analyze the expression and function of the PPAR genes in STAD cell lines (AGS and SGC7901 cells).

Results
PPARA, PPARD and PPARG were more abnormally expressed in STAD samples and cell lines when compared to most of 32 type cancers in TCGA. In STAD, the expression of PPARD was higher in Grade 3+4 and male patients, while that of PPARG was higher in patient with Grade 3+4 and age > 60. Patients in high-PPARA expression group tended to have longer survival time. Co-expression analysis revealed 6 genes significantly correlated with the three PPAR genes in STAD. Single-sample GSEA (ssGSEA) showed that the three PPAR genes were enriched in 23 pathways, including MITOTIC_SPINDLE, MYC_TARGETS_V1, E2F_TARGETS and were closely correlated with immune cells, including NK_cells_resting, T_cells_CD4_memory_resting, and macrophages_M0. Immune checkpoint genes (CD274, SIGLEC15) were abnormally expressed between high-PPAR expression and low-PPAR expression groups. TTN, MUC16, FAT2 and ANK3 genes had a high mutation frequency in both high-PPARA/PPARG and low-PPARA/PPARG expression group. Fourteen and two PPARA/PPARD drugs were identified to be able to effectively treat patients in high-PPARA/PPARG and low-PPARA/PPARG expression groups, respectively. We also found that the chemotherapy drug Vinorelbine was positively correlated with the three PPAR genes, showing the potential of Vinorelbine to serve as a treatment drug for STAD. Furthermore, cell experiments demonstrated that PPARG had higher expression in AGS and SGC7901 cells, and that inhibiting PPARG suppressed the viability, migration and invasion of AGS and SGC7901 cells.

Conclusions
The current results confirmed that the three PPAR genes (PPARA, PPARD and PPARG) affected STAD development through mediating immune microenvironment and genome mutation.
Effect of high intensity circuit training on muscle mass, muscular strength, and blood parameters in sedentary workers
Authors: Ho Sung-Yen , Chung Yu-Chun , Wu Huey-June , Ho Chien-Chang , Chen Hung-Ting 
Published: March 2024

Background
The study aim was to investigate the effect of high intensity circuit training on body composition, muscular performance, and blood parameters in sedentary workers.

Methods
A total of 36 middle-aged sedentary female workers were randomly divided into high intensity circuit training (HICT) group, aerobic training (AT) group, and control (CON) group. The exercise training groups performed exercise three times per week for 8 weeks. In HICT, each session was 20–35 min with 2–3 rounds. Rounds were 8 min; the interval between rounds was 4–5 min. In AT, each exercise session comprised 20–35 min of aerobic dance training. Physiological parameters were measured 1 week before and after the interventions. The resulting data were analyzed using two-way mixed design ANOVA, the differences in body composition, muscular performance and blood parameters before and after training were compared.

Results
The muscle mass (pre-test: 21.19 ± 2.47 kg; post-test: 21.69 ± 2.46 kg, p < 0.05) and knee extension 60°/s (pre-test: 82.10 ± 22.26 Nm/kg; post-test: 83.47 ± 12.83 Nm/kg, p < 0.05) of HICT group were significantly improved, with knee extension 60°/s significantly higher than that of the CON group (HICT: 83.47 ± 12.83 Nm/kg; CON: 71.09 ± 26.53 Nm/kg). In the AT group, body weight (BW) decreased significantly (Pre-test: 59.37 ± 8.24 kg; Post-test: 58.94 ± 7.98 kg); no significant change was observed in CON group. The groups exhibited no significant change in blood parameters (hs-CRP, TC, and LDL-C) or IGF-1.

Conclusions
Sedentary worker’s muscle mass and lower-limb muscular performance were effectively improved by performing 8-week HICT with the benefits of short duration, no spatial constraints, and using one’s BW, whereas AT caused a significant decrease in BW. However, the AT induced decrease in BW was probably an effect of muscle loss rather than exercise-induced weight loss.
Combined detection of serum IL-6 and CEA contributes to the diagnosis of lung adenocarcinoma in situ
Authors: Pan Jing , Zhuang Wanzhen , Xia Yu , Huang Zhixin , Zheng Yue , Wang Xin , Huang Yi 
Published: March 2024

Background
Effective discrimination of lung adenocarcinoma (LUAD) in situ (AIS) from benign pulmonary nodules (BPN) is critical for the early diagnosis of AIS. Our pilot study in a small cohort of 90 serum samples has shown that serum interleukin 6 (IL-6) detection can distinguish AIS from BPN and health controls (HC). In this study, we intend to comprehensively define the diagnostic value of individual and combined detection of serum IL-6 related to the traditional tumor markers carcinoembryonic antigen (CEA) and cytokeratin 19 fragment (CYFRA21-1) for AIS.

Methods
The diagnostic performance of serum IL-6 along with CEA and CYFRA21-1 were evaluated in a large cohort of 300 serum samples by a chemiluminescence immunoassay and an electrochemiluminescence immunoassay. A training set comprised of 65 AIS, 65 BPN, and 65 HC samples was used to develop the predictive model for AIS. Data obtained from an independent validation set was applied to evaluate and validate the predictive model.

Results
In the training set, the levels of serum IL-6 and CEA in the AIS group were significantly higher than those in the BPN/HC group (P < 0.05). There was no significant difference in serum CYFRA21-1 levels between the AIS group and the BPN/HC group (P> 0.05). Serum IL-6 and CEA levels for AIS patients showed an area under the curve (AUC) of 0.622 with 23.1% sensitivity at 90.7% specificity, and an AUC of 0.672 with 24.6% sensitivity at 97.6% specificity, respectively. The combination of serum IL-6 and CEA presented an AUC of 0.739, with 60.0% sensitivity at 95.4% specificity. The combination of serum IL-6 and CEA showed an AUC of 0.767 for AIS patients, with 57.1% sensitivity at 91.4% specificity in the validation set.

Conclusions
IL-6 shows potential as a prospective serum biomarker for the diagnosis of AIS, and the combination of serum IL-6 with CEA may contribute to increased accuracy in AIS diagnosis. However, it is worth noting that further research is still necessary to validate and optimize the diagnostic efficacy of these biomarkers and to address potential sensitivity limitations.
Effectiveness of therapeutic ultrasound on reducing pain intensity and functional disability in patients with plantar fasciitis: a systematic review of randomised controlled trials
Authors: Alhakami Anas Mohammed , Babkair Reem Abdullah , Sahely Ahmad , Nuhmani Shibili 
Published: March 2024

Background
Ultrasound therapy is one of the preferred conservative treatments for patients with plantar fasciitis. This study aims to evaluate the effectiveness of therapeutic ultrasound in decreasing pain intensity and improving functional disability in patients with plantar fasciitis.

Methods
Five randomised control trials (RCT) were selected based on an electronic search in PubMed, Trip Database and PEDro. To be included in the systematic review, the study should be an RCT which investigated the effectiveness of therapeutic ultrasound conducted in patients with plantar fasciitis with pain intensity and functional disability as outcome measures. Only studies published in peer-reviewed journals written in the English language were included. The quality of the selected studies was measured by the PEDro scale.

Results
All the included studies showed that ultrasound therapy is beneficial in reducing pain score and improving functional disability, except one study did not recommend using ultrasound therapy for plantar fasciitis. Moreover, regarding another outcome measure, two studies found that ultrasound therapy reduces thickness and tenderness in plantar fasciitis and improves static and dynamic balance.

Conclusion
After reviewing the five studies, this systematic review support using ultrasound therapy to decrease pain and improve functional disability in patients with plantar fasciitis.

Study Registration
https://osf.io/xftzy/.
Instrumentation, data evaluation and quantification in on‐line aerosol mass spectrometry
Authors: Hinz Klaus‐Peter , Spengler Bernhard 
Published: June 2007

AbstractOn‐line micro‐ and nanoparticle mass spectrometry has evolved into a prominent analytical method for the characterization of airborne particles, particle populations and aerosols over the recent years, driven by essential developments in instrumentation, data evaluation and validation. In this tutorial, the fundamental aspects of the technology and methodology for qualitative and quantitative on‐line aerosol particle analysis are discussed. Specific properties of the on‐line mass spectrometric instrumentation for particle analysis are described, combined with a discussion of basic differences of the instruments and demands for future improvements of instruments and data analysis techniques. Optimized technology and methodology in particle analysis is expected to lead to essential growth of the knowledge and to quality improvement of the description of atmospheric processes and health effects in the future. Copyright © 2007 John Wiley & Sons, Ltd.
Apnea–hypopnea index as the outcome variable in multiple linear regression analysis: Statistical issues
Authors: Chan Chung‐hong , Ng Daniel K. 
Published: June 2007

AbstractBackgroundIt is common for apnea–hypopnea index (AHI) to be used as an outcome variable in ordinary least squares linear regression. However, the distribution of AHI is not tested. The assumption of ordinary least squares linear regression may be violated.MethodsThe distribution of AHI from a pediatric sleep laboratory was assessed by Kolomgorov–Smirnov test. Transformation of AHI was attempted. In addition, we fitted an ordinary linear regression model (OLSM) and negative binomial regression model (NBRM) of the relationship between body mass index and the rate of apnea and hypopnea events. OLSM and NBRM were evaluated by residuals analysis.ResultsAHI from the studied population deviated significantly from normal distribution. Commonly used transformation algorithm could not transform AHI to normal distribution. In addition, OLSM violated the underlying statistical assumptions of homogeneity of variance and normality of error. NBRM, on the other hand, was not restricted by these assumptions.ConclusionThe current study suggested AHI is not likely to be normally distributed and its distribution cannot be transformed to normal. Negative binomial regression of the total number of apnea and hypopnea with an offset of log TST should be used in data analysis. Pediatr Pulmonol. 2007; 42:711–715. © 2007 Wiley‐Liss, Inc.
Adolescent Depression: A Review
Authors: Parker Gordon , Roy Kay 
Published: June 2007

Objective: To review the characteristic clinical, illness course and risk factors to adolescent depression. Method: A literature review is provided with interpretive comments. Results: The clinical feature profile is likely to reflect the rarity of melancholic depression, while the non-melancholic ‘irritable hostile’ pattern appears distinctly increased. A ‘reactive depressive disorder’ is rare in those who get to psychiatric assessment, while comorbidity (e.g. anxiety and personality disorders, illicit drug use) is the rule. Aetiological determinants and the prognosis generally more relate to comorbid factors than to depression per se. Predisposing and precipitating psychological and social determinants are considered, while the efficacies of varying antidepressant strategies remain unclear apart from those withan ‘anxious’ or ‘irritable’ depression where selective serotonin re-uptake inhibitor medication has shown utility and where cognitive–behavioural therapy may be relevant. Conclusions: For the majority who develop adolescent depression, its expression and outcome appear more a reflection of the propagating determinants, most commonly anxiety and personality style. The clinician should determine a treatment plan that not only addresses the depression but which identifies and addresses the contributing features.
Prevalence of Psychiatric Disorder in a Methadone Maintenance Population
Authors: Callaly Tom , Trauer Tom , Munro Leigh , Whelan Greg 
Published: June 2007

Objective: The objective of this study was to examine the prevalence of psychiatric disorders in a group of patients who had recently entered a methadone maintenance programme. Method: A total of 62 patients were interviewed using the Composite International Diagnostic Interview (CIDI) within 6 months of commencing methadone maintenance. The CIDI was used to establish symptoms of psychiatric illness at interview and in the 12 months prior. Results: In the 12 months prior to interview, 76% of the sample fulfilled ICD-10 criteria for a psychiatric disorder other than substance-use disorder. Over half of the group interviewed fulfilled ICD-10 criteria for an affective disorder, two-thirds fulfilled criteria for an anxiety disorder and just under half fulfilled diagnostic criteria for both an affective disorder and an anxiety disorder in the 12 months prior to interview. At the time of interview, 19% fulfilled ICD-10 diagnostic criteria for a moderate or severe affective disorder. Seventy per cent of males and 89% of females interviewed had a comorbid psychiatric illness. In 71% of the group who had a comorbid psychiatric illness, the onset of psychiatric symptomatology was reported to predate the use of heroin. Conclusion: The prevalence of psychiatric disorder is up to 10 times higher in the population on methadone maintenance than in the general population and is two to three times higher than that found in community surveys of those with a substance-use disorder. These results are consistent with earlier findings and have implications for service planning.
Bilateral Orbitomedial Leucotomy for Obsessive–Compulsive Disorder: A Single-Case Study Using Positron Emission Tomography
Authors: Sachdev Perminder , Trollor Julian , Walker Alexandra , Wen Wei , Fulham Michael , Smith John Sydney , Matheson John 
Published: June 2007

Objective: The objective of this report is to correlate the clinical outcome of neurosurgery for obsessive–compulsive disorder (OCD) with regional cerebral glucose metabolic changes. Clinical picture: The patient was a 37-year-old female patient with severe and intractable OCD. Treatment: The patient was treated with bilateral stereotactic lesions in the frontal white matter superior to the orbito-medial cortex. Outcome: She had a remarkable improvement in her obsessive–compulsive symptoms, which was sustained up to 3 years of follow up. A positron emission tomography (PET) scan performed 18 days after surgery demonstrated an obvious reduction of metabolism in the caudate head, anterior cingulate and orbital, medial and lateral prefrontal cortices and the thalamus. At 1 year postsurgery, metabolic rate was still reduced in the anterior cingulate gyrus, caudate and thalamus compared with preoperative baseline. The patient demonstrated no long-term cognitive effects of the surgery. Conclusions: This case supports some of the cortical-subcortical circuit dysfunction models of OCD and argues for the further evaluation of neurosurgery for the treatment of a severe and intractable disorder.