bluuebunny/crossref_metadata_2025_split huggingface dataset:
Risk factors analysis of hypofibrinogenemia associated with tigecycline
Authors: Liu Jiheng , Yuan Xuefeng , Wen Long , Tan Xin , Sui Qian , Liu Xiaohui 
Published: March 2024

Abstract
Purpose: This aim of this study was to analyze the effect of tigecycline on blood coagulation parameters and identify which variables may be related with it.
Patients and methods: This is a retrospective and observational study conducted in a tertiary general hospital in China. All patients over 18 years old, who received tigecycline for >48 hours were included. After treatment with tigecycline, patients were divided into two groups according to fibrinogen plasma concentration< 2.0 g/L. Data of patients were collected. Multivariate logistic regression was performed to identify risk factors for hypofbrinogenemia associated with tigecycline.
Results: 50 patients (71.3 ±20.2 years) were analyzed. The median duration of treatment was 8 days (3～20). 24 patients develoed hypofibrinogenemia, 3 gastrointestinal bleeding events were observed and 4 of them required fibrinogen administration. We identified the cumulative dose (OR =15.28, IC 95% 2.10-111.02, p = 0.01) and the baseline direct bilirubin >0.4mg/dL (OR =5.79, IC 95% 1.13-27.98, p = 0.04) as risk factors for tigecycline induced hypofibrinogenemia, while the baseline fibrinogen (OR =0.53, IC95% 0.29-0.97, p = 0.04) was likely a protective factor.
Conclusions:Tigecycline administration may be related with hypofibrinogenemia. Medical workers should realize that the use of tigecycline may induce hypofibrinogenemia or even serious adverse reactions, and monitor the coagulation routine during treatment, especially when the cumulative dose of tigecycline was greater or liver dysfunction especially direct bilirubin abnormality.
Tumor Blood Volume Measurement in Brain Gliomas Using Velocity-Selective Arterial Spin Labeling
Authors: Qu Yaoming , Ma Andong , Yan Xinran , Ou Xiaochan , Zou Xia , Rui Qihong , Wen Haitao , Wang Xianlong , Zhu Dan , Qin Qin , Wen Zhibo 
Published: March 2024

Abstract

Background
To evaluate the feasibility and performance of velocity selective (VS) ASL based cerebral blood volume (CBV) mapping among glioma patients in clinical practice, comparing with the VSASL based cerebral blood flow (CBF) mapping and dynamic susceptibility contrast-enhanced perfusion-weighted imaging (DSC-PWI).
Methods
This study included patients with histologically proven brain glioma who underwent preoperative MRI including VSASL based CBV, CBF and DSC-PWI between 2017 and 2021. Visual inspection was performed to evaluate the lesion conspicuity on VSASL derived CBV maps based on 1–3 criteria by comparing to the surrounding parenchyma. The relative values of maximum tumor blood volume (rTBV) and tumor blood flow (rTBF), derived from VSASL or DSC-PWI were compared between low-grade and high-grade glioma. Linear regression and Bland–Altman analyses were constructed to evaluate the correlation and agreement of rTBV measurements between VSASL method and DSC-PWI. The diagnosis ability for discrimination between low- and high-grade glioma were evaluated using ROC curves.
Results
Forty-eight participants (mean age, 45 ± 13 years; 25 men; 23 high-grade gliomas) were evaluated. The lesion conspicuity of VSASL based CBV maps was good on visual inspection (averaged scores: 2.26 ± 0.76, weighted kappa of 0.8 between readers). Moreover, VSASL provided highly correlated quantifications of rTBV (R2 = 0.83, p < 0.001) compared to DSC-PWI, and further improved diagnostic performance than VSASL derived rTBF measurements (ROC AUC = 0.94 vs. 0.89).
Conclusions
VSASL served as a promising and accurate means in quantification of TBV for glioma stratification in clinical patients, indicating its potential as a viable non-contrast alternative to DSC-PWI for brain tumor applications.
Biofilm biofertilizer manipulates toxic heavy metals and micronutrients in the soil-plant systems in Sri Lanka to produce high-quality rice: a sign of ecosystem intelligence
Authors: Warnakulasooriya Dilan , Premarathna Mahesh , Ekanayake Sidath , Seneviratne Gamini 
Published: March 2024

Abstract
High toxic heavy metals (THM) and low micronutrient contents in rice grains affect adversely on human health. Here we investigated the potential of using biofilm biofertilizer (BFBF) in managing THM and micronutrients in rice by conducting field experiments that compared BFBF practice with the chemical fertilizer (CF) alone practice in Sri Lanka. Bioaccumulation and translocation factors were evaluated to assess the THM and micronutrient distribution in soil-plant systems. The human health risk was also estimated. The BFBF practice showed a significant reduction in estimated daily intakes of the THM like As, Co, Cd, and Cr compared to the CF practice, thus decreasing hazard quotient (HQ) and hazard index (HI) values for lowering health risk. In the CF practice, the translocation of As from panicle to rice seed was significantly increased, and As in rice seeds is reported to exceed the safe level in some cases in Sri Lanka. On the contrary, reduced translocation of As, and increased translocation of Cr within the safe level to rice seeds with the BFBF application were observed, implying a sign of intelligence in the paddy ecosystem. Interestingly, the HI had been kept below the threshold value by significantly reducing the HQ values of each THM, only in the BFBF practice. These results highlight the role of increased microbial diversity and abundance induced by the BFBF, in mitigating the health risks and enhancing the sustainability of the soil-plant system, a clear sign of ecosystem intelligence.
Source Forecasting and Economic/Environmental Assessment of Hybrid Renewable Energy System in North Eastern State of India
Authors: Komanapalli Vahini , Mansani Swapna , Hampannavar Santoshkumar , B Deepa 
Published: March 2024

Abstract
Clean and sustainable energy holds preeminent importance from a socio-environmental standpoint and can be achieved through the implementation of a Hybrid Renewable Energy System (HRES). As well as ensuring the stable and reliable operation of power systems amidst the increasing integration of renewable energy sources, precise source forecasting becomes indispensable. Thus, this paper presents a pioneering HRES design incorporating Photovoltaic (PV), Wind Turbine (WT), and Biogas Generator (Bio) technologies, wherein animal manure is utilized as biomass for the sustainable valorization of animal waste. The preliminary objective of this study is to address the prevailing gaps to attain sustainable energy production that is both cost-optimal and technically efficient. Consequently, this paper investigates source forecasting through time series modeling, and assesses the techno-environmental and economic viability of HRES (both off-grid and on-grid) within the northeastern state of India, specifically focusing on the case study of the Cachar district in Assam state. Moreover, real data analysis is conducted to model and optimize the hybrid system. The findings reveal promising outcomes in terms of cost, emissions, and electrical energy potential, which are presented and comprehensively discussed. Furthermore, a sensitivity analysis is performed to assess the system's robustness. The analyzed results are compared and validated with existing literature including different energy economics with optimum configurations. Finally, this study endeavors to project a future power system for one of the prominent regions in Assam, an Indian state.
Surgical management of the consequences of ventral fixation failed due to severe osteoporosis (a case study)
Authors: Shuvalov Stanislav D. , Shulga Aleksey E. , Tolkachev Vladimir S. , Bazhanov Sergey P. , Ostrovskij Vladimir V. 
Published: March 2024

Abstract
The patients with spinal traumas due to osteoporosis are one of the most challenging cohorts as 15-35% of cases feature adverse outcomes including advanced kyphotic deformities and chronic compression of the spinal canal structures that lead to the progression of neurological symptoms. As the bone mineral density in those patients is low, their surgical management is associated with a higher risk of adverse outcomes. However, the studies on the surgical management of this pathology do not present a clear understanding of the preferred surgical techniques. Thus, the investigation of surgical outcomes in severe osteoporosis patients with spinal trauma is a major issue for neurosurgery, neurology, traumatology, orthopedics, and rehabilitation.
The objective of this research is to analyze the causes and consequences of the adverse surgical outcomes in an osteoporosis patient with a neglected Th12 injury, as well as to present the immediate outcome of the revision surgical management.
Material and methods. A case study of the surgical management in a 76-year-old female patient who suffered from an uncomplicated thoracic spine injury caused by her own height falling. As the conservative treatment turned inefficient, and clinical and radiological dynamics were negative, in 3 months after the injury he underwent a surgical management: right thoracophrenotomy, resection of the Th12 vertebral body with the spinal cord anterior decompression, Th10-L1 deformity correction and fixation with a ventral system and screws augmentation with bone cement, anterior supporting spinal fusion with a mesh endofixator. Soon after the surgery all neurological symptoms completely regressed, but 2 months later the patient’s severity of pain progressively increased to 10 scores in an upright position. As the previous densitometry study revealed severe osteoporosis in the patient’s lumbar spine, and he also featured clinical and radiological signs of unstable anterior fixation, the case conference made a decision to stabilize the patient’s thoracolumbar spine with a polysegmental screws-and-hooks dorsal system with screw elements augmented with bone cement.
Results. The investigation of the patient V’s surgical outcomes revealed no loss of correction or signs of the structure instability. Her neurological status featured no negative dynamics. The patient's gait is firm, he needs no additional support.
Conclusion. This case study proves the higher risk of the ventral fixation instability in osteoporosis patients as well as the possible need to increase the structure length. The active surgical technique and comprehensive rehabilitation management in spinal injury patients ensures complete functional restoration of lost functions.
Completeness of Radiology Request Forms at Hawassa University Comprehensive Specialized Hospital, Sidama Region, Ethiopia
Authors: Baye Andargie 
Published: March 2024

Abstract
Background
Radiology request forms are essential communication tools between the physician and the radiologist. Complete, accurate and justified radiological examination requests are prerequisite to radiological exposures. However, global research showed evidence of high numbers of incomplete and inaccurate requests as well as that up to 77% radiological exposures are unjustified. This research is designed to measure the completeness, of Computed Tomography (CT), Magnetic resonance imaging (MRI), Ultrasound and X-ray request forms sent from different units to departments of radiology at Hawassa University Comprehensive Specialized Hospital (HUCSH). This research had positive effects on optimization of radiation protection.
Method
Hospital based cross sectional study design was conducted to assess the completeness of Radiology request forms at the radiology department of HUCSH. A review of all consecutive request forms received during data collection time (CT Scan, MRI, and Ultrasound) and for x-ray by using systematic random sampling method to assess the completeness of filling of the forms, details of clinical information, previous exposure and information about the requesting physician. Probability sampling method (stratified and systematic random sampling) used to select 385 request forms over a period of one month.
Result
This study generally demonstrated many of the data on the request form were incompletely filled. Patient’s full name, Age, Gender, Requested anatomic body part, MRN were the highest filled data in all the requests with a frequency of 98.4%,98.2%,97.4%,99.7%,96.1% In contrary, the least filled data were Previous imaging history(5/385(1.3%)), Address(6/385(1.6%)),History of previous IV contrast reaction(22/385(5.7%)), Relevant lab information ((23/385) (6%)) and History of allergy(94/385(24.4%)), had low filling rate for all modalities.
Conclusion
The completeness of the Radiology request forms was substandard and it should be improved.
Entrevista: Professor Thierry Ardouin e a pesquisa em torno da Formação Profissional
Authors: Ardouin Thierry , Vieira Alves Francisco Regis 
Published: March 2024

O presente texto integra o primeiro volume da Revista Ensino em Debate (REDE) e tem por objetivo apresentar um diálogo com o professor e pesquisador da Universidade de Rouen Normandie, França, Prof. Dr. Thierry Ardouin, sobre sua trajetória formativa e profissional, bem como suas pesquisas sobre formação de adultos e, de modo especial, sobre a noção de Engenharia de Formação (l’ingénierie de formation). A noção de Engenharia de Formação possui extensa e longa tradição na cultura francesa e apresenta sua gênese em um amplo contexto que ultrapassa os interesses específicos pedagógicos e educacionais. O leitor poderá constatar que Thierry Ardouin explica sobre suas origens francesa, latina e anglo saxônica. Ademais, sob um viés de inovação pedagógica aplicada ao campo de formação profissional e educacional, a noção de Engenharia de Formação (l’ingénierie de formation) consolidou espaço e passou a ser utilizada por pesquisadores de matizes variados. De modo especial, quando examinamos o caso da França-Brasil, podemos constatar o emprego de tal noção no campo da Didática da Matemática, segundo a tradição francesa, que apresenta a noção de Engenharia Didática de Formação. Por fim, na entrevista, optamos por trazê-la em francês, mantendo o idioma de origem do entrevistado.
Palavras-chave: Formação profissional; Engenharia de Formação; Formação de adultos; Ensino.
Improving Study Decisions at Private Universities: The Role of Family, Price, and University Image
Authors: Budaya Indra , Liantifa Melifia , Sarmigi Elex , Lestari Anggia Ayu 
Published: March 2024

AbstractThis study examines and analyses the role of family factors on prices and brands on student decisions to choose private universities to continue their studies. This study involved 500 students from various private universities in Jambi Province to serve as samples. The results showed that in the first model, price and brand influenced the decision to choose private universities (PTS) in Jambi province, and the magnitude of the effect was 63.9%. Price, Brand and Family in the second model significantly affect the Selection Decision of Private Universities (PTS) in Jambi Province, with the magnitude of the influence being 75.5%. In the third model, the family plays a role or can moderate the impact of price and brand on choosing private universities (PTS) in Jambi Province. Keywords:Lecture Decisions; Family; Price; Brand; Private College
Group Acceptance and Commitment Therapy for Recovery From Psychosis: Protocol for a Single-Group Waitlist Trial
Authors: Cugnetto Marilyn L , Morris Eric M J , Bonfield Siobain F , Gates Jesse , Morrison Ilona , Newman Ellie R , Nicholls Julia D , Soares Lisa M , Antonucci Megan T , Clemente Jacinta R , Garratt Claire L M , Goldstone Eliot , Pavone David A , Farhall John 
Published: March 2024

Background
Psychological interventions, along with antipsychotic medications, are recommended for adults diagnosed with a psychotic disorder. While initially designed to mitigate positive symptoms, psychological interventions targeting personal recovery were developed and aligned with the recovery framework that many mental health services have adopted. Acceptance and Commitment Therapy (ACT) for psychosis is one such intervention that shows promise when delivered in an individual format. There is preliminary evidence that ACT for psychosis in a group format improves recovery.

Objective
This trial aims to evaluate the effectiveness of the “Recovery ACT” group program on personal recovery among adults living with a psychotic disorder.

Methods
Our unfunded study is a multiagency, prospective, nonrandomized, waitlist control, single-group trial of the Recovery ACT group program. The program involves 7 weekly group sessions of 90 minutes duration and a 90-minute booster session held 1 month later. We intend to recruit 160 adults living with a psychotic disorder who enroll in a group that is offered as a routine clinical service at participating public mental health services in Melbourne, Victoria, Australia. The 4 assessment time points are 4-6 weeks before the start of the group program, at the start of the group program, at the end of the group program, and at the booster session. There is an optional midgroup assessment and follow-up study. The primary outcome is personal recovery. Secondary outcomes include participants’ well-being and psychological flexibility processes. Qualitative data are also collected from participants and facilitators.

Results
Recruitment began in September 2019 and is ongoing until 2024, subsequent to a 24-month disruption due to the COVID-19 pandemic. As of the submission of this paper, 93 participants consented to the evaluation, 65 completed T1 measures, and 40 had a complete data set for the proposed analyses.

Conclusions
This is the first trial evaluating the effectiveness of the Recovery ACT group program on personal recovery for adults living with a psychotic disorder. Findings will contribute to knowledge about psychosocial interventions for adults living with psychosis. This trial may also serve as an example of a partnership between clinicians and academics that can facilitate the translation of research into practice.

Trial Registration
Australian New Zealand Clinical Trials Registry ACTRN12620000223932; https://anzctr.org.au/Trial/Registration/TrialReview.aspx?ACTRN=12620000223932

International Registered Report Identifier (IRRID)
DERR1-10.2196/49849
Hubungan Antara Self Concept Dengan Penyesuaian Diri Mahasiswa Baru
Authors: Ayu Ningrum Devy Sekar , Pratiwi Endah Andriani 
Published: March 2024

AbstractÂ The purpose of this study was to determine the relationship between Self Concept and Self-Adjustment of New Students in Guidance and Counseling Study Program of IKIP SILIWANGI. The method used in this study is a correlational method with a quantitative approach. The theory used in this study is the theory of Self Concept proposed by William H Fitts (1971) and the theory of adjustment proposed by Alexander Schneiders (1964). The sampling technique in this study used simple random sampling, the number of samples in this study were 40 new students of the Guidance and Counseling study program at IKIP SILIWANGI. The measuring instrument used in this study is the adaptation of the Tennessee Self-Concept scale (TSCS) developed by William H. Fitts (1971) and the measuring instrument for social adjustment is a measuring instrument made by researchers based on aspects of social adjustment based on theory. from Schneiders (1964). The results of the study obtained test results with a value of tcount (2.595) > ttable (2.021). This indicates that Ho is rejected, which indicates that there is a positive relationship between the Self concept variable and the adjustment of New Students in the Guidance and Counseling Study Program of IKIP SILIWANGI.Keywords:Â Â Self Concept, Self Adjustment, StudentsÂ Â Â AbstrakÂ Tujuan dari penelitian ini adalah untuk mengetahui Hubungan antara Self Concept dengan Penyesuaian Diri Mahasiswa Baru di Prodi Bimbingan dan Konseling IKIP SILIWANGI. Metode yang digunakan dalam penelitian ini adalah metode korelasional dengan pendekatan kuantitatif. Teori yang digunakan dalam penelitian ini adalah teori Self Concept yang dikemukakan oleh William H fitts (1971) dan teori penyesuaian diri yang di kemukakan oleh Alexander Schneiders (1964). Teknik pengambilan sampel dalam penelitian ini menggunakan simple random sampling, jumlah sampel dalam penelitian ini adalah 40 mahasiswa baru program studi Bimbingan dan Konseling di IKIP SILIWANGI. Alat ukur yang dipakai dalam penelitian ini adalah adaptasi alat ukur Tennessee Self-Concept scale (TSCS) yang dikembangkan oleh William H. Fitts (1971) dan alat ukur untuk penyesuaian sosial adalah alat ukur yang dibuat oleh peneliti berdasarkan aspek-aspek penyesuaian sosial berdasarkan teori dari Schneiders (1964). Hasil dari penelitian didapatkan hasil pengujian dengan nilai thitung (2,595) > ttabel (2,021). Hal tersebut mengindikasikan Ho ditolak yang menunjukkan bahwa terdapat hubungan yang positif antara variabel Self concept dengan penyesuaian diriÂ pada Mahasiswa Baru di Prodi Bimbingan dan Konseling IKIP SILIWANGI.Kata Kunci: Self Concept, Penyesuaian Diri, Mahasiswa
HUBUNGAN KELEKATAN DENGAN TINGKAT KEDUKAAN PADA ORANG DEWASA
Authors: Asih Muflihah Mustika , Arumsari Cucu , Isti'adah Feida Noorlaila 
Published: March 2024

Kedukaan merupakan sebuah kondisi yang dialami ketika seseorang ditinggalkan oleh orang yang dicinta. Kelekatan yang tumbuh karena adanya cinta dan kasih sayang antara suami dan istri dapat menjadi penyebab orang mengalami kedukaan saat salah satu dari mereka meninggal dunia. Tujuan dari penelitian ini adalah mengetahui gambaran kedukaan dan kelekatan pada orang dewasa yang ditinggal meninggal pasangan hidupnya di Desa Sukasukur, hubungan antara kedukaan dan kelekatan, serta implikasi terhadap bimbingan dan konseling. Metode penelitian yang digunakan adalah korelasional sebagai cara untuk mengungkap hubungan antara kedukaan dan kelekatan. Sampel penelitian merupakan orang dewasa sebanyak 93 dimana setiap anggota populasi dijadikan sampel berdasarkan pengambilan sampel menggunakan teknik sampel jenuh. Hasil dari penelitian ini yaitu gambaran umum kelekatan yang dipengaruhi oleh tingginya secure attachment serta rendaahnya ketiga aspek kelekatan lainnya, sedangkan pada kedukaan berada pada kategori sedang sebesar 53%. Terdapat pula korelasi antara kelekatan dan kedukaan sebesar 0,1738 > 0,1716 yang dapat diartikan bahwa keduanya memiliki hubungan yang sangat rendah.Â Â
Profile of Students' Interpersonal Communication Level at SMA Negeri 9 Semarang
Authors: Noores Vendilla , Suhendri Suhendri , Pujowati Menur 
Published: March 2024

Penelitian ini di latar belakangi dengan adanya peserta didik yang memiliki komunikasi interpersonal kurang baik. Penelitian ini bertujuan untuk mengetahui tingkat komunikasi interpersonal pada peserta didik kelas X SMA Negeri 9 Semarang. Penelitian ini merupakan penelitian dengan pendekatan kuantitatif dan metode studi deskriptif. Populasi penelitian ini adalah kelompok usia remaja di SMA Negeri 9 Semarang dengan jumlah sampel 396 terdiri dari kelas X sebanyak 11 kelas dengan rata rata satu kelas 36 responden. Jumlah sampel dalam penelitian ini adalah 199 peserta didik kelas X dengan teknik pengambilan sampel menggunakan simple random sampling. Hasil penelitian ini menunjukan bahwa tingkat komunikasi interpersonal di SMA Negeri 9 Semarang Tahun Ajaran 2023/2024 dengan presentase Tingkat Komunikasi Interpersonal masuk dalam kategori rendah berjumlah 44 peserta didik dengan persentase 22,11%, sedangkan kategori sedang berjumlah 134 peserta didik dengan persentase 67,34%, dan juga kategori tinggi yang berjumlah 21 peserta didik dengan persentase 10,55%. Hal tersebut dapat menggambarkan bahwa jumlah tingkat komunikasi interpersonal terbanyak pada siswa kelas X SMA Negeri 9 Semarang berjumlah sekitar 134 peserta didik termasuk dalam kategori Sedang. Dalam penelitian ini menunjukan bahwa komunikasi interpersonal yang di miliki peserta didik kelas X di SMA Negeri 9 Semarang Tahun ajaran 2023/2024 berada pada rata-rata di kategori sedang.