bluuebunny/crossref_metadata_2025_split huggingface dataset:
Constitutional Conventions Concerning the Judiciary beyond the Common Law
Authors: Kosař David , Vincze Attila 
Published: March 2024

AbstractConstitutional conventions are traditionally understood as socially binding, usually unwritten, rules of constitutional importance based on precedent which cannot be enforced before courts. This traditional approach has several limitations, because it debates the normative quality of conventions rather than how to find them and where the real power lies. By doing so it is disconnected from scholarship on informal institutions in social sciences. Moreover, scholarship on constitutional conventions focuses predominantly on common law countries and conventions concerning political branches. This article pushes the boundaries in both directions. It shows how constitutional conventions can be conceptualized in civil law jurisdictions, and also identifies informal practices and constitutional conventions governing the judiciaries. On a broader level, it argues that constitutional conventions as a normative concept can help to filter the informal practices and differentiate between simple repetitive behavior on the one hand and conventions as a subset of informal institutions on the other.
Color-avoiding percolation and branching processes
Authors: Fekete Panna Tímea , Molontay Roland , Ráth Balázs , Varga Kitti 
Published: March 2024

AbstractWe study a variant of the color-avoiding percolation model introduced by Krause et al., namely we investigate the color-avoiding bond percolation setup on (not necessarily properly) edge-colored Erdős–Rényi random graphs. We say that two vertices are color-avoiding connected in an edge-colored graph if, after the removal of the edges of any color, they are in the same component in the remaining graph. The color-avoiding connected components of an edge-colored graph are maximal sets of vertices such that any two of them are color-avoiding connected. We consider the fraction of vertices contained in color-avoiding connected components of a given size, as well as the fraction of vertices contained in the giant color-avoidin g connected component. It is known that these quantities converge, and the limits can be expressed in terms of probabilities associated to edge-colored branching process trees. We provide explicit formulas for the limit of the fraction of vertices contained in the giant color-avoiding connected component, and we give a simpler asymptotic expression for it in the barely supercritical regime. In addition, in the two-colored case we also provide explicit formulas for the limit of the fraction of vertices contained in color-avoiding connected components of a given size.
State Violence and Pains of Punishment: Experiences of Incarcerated Women in Belarus in the Aftermath of the 2020 Protests
Authors: Chulitskaya Tatsiana , Matonyte Irmina 
Published: March 2024

AbstractState violence against Belarusian women involved in protest activities after the fraudulent presidential election in 2020 and onward has been unprecedented in the country’s history. Women’s activism has challenged the patriarchal authoritarian regime, which was ill-prepared to deal with women. However, after a short period of adaptation by the repressive institutions, women became their “special clients.” With reference to gender-sensitive academic research, we investigate diverse forms of state violence against women and analyze how they perceive their experiences of incarceration for political reasons. This article is based on available datasets, a series of nine semi-structured interviews, and insights from participant observation. The research reveals that Belarusian women incarcerated for political reasons fall under the “demanding clients” category: they comprehensively challenge the state-sponsored brutal patriarchy and expect the repressive apparatus to meet their specific needs. These women experience multidimensional physical discomfort and psychological pressure, including targeted offensive and dehumanizing elements. At the same time, incarcerated women do not feel ostracized by society; they share the feeling that their “crimes” are supported by civil society, and they endure the pains of punishment as targeted violence from a state fighting cynically for its own survival.
Government-Coordinated Internal Colonization in the Era of Nationalism: The Case of Dualist Hungary
Authors: Berecz Ágoston 
Published: March 2024

AbstractBetween 1881 and 1914, Hungarian governments established at least 36 agricultural colonies in today’s territory of Romania (nine new villages and 25 neighborhoods attached to existing ones). After 1894, a separate government fund was created for land purchases and the venture was entrusted to a Department of Colonization within the Ministry of Agriculture. This article gives an archival-based account of the political, financial, agricultural, and logistical aspects of the settlement program and compares it with its better-researched Prussian model. Investigating it as a series of interactions between settlers, the dedicated government agency, local potentates, and the surrounding population, it identifies structural impediments to the endeavor. Although there was a broad unity across political parties behind the idea of conquering new territories for the ethnic nation, the settlement program rested on a fragile consensus within the elite. Its expansion after 1900 was mainly due to Minister Ignác Darányi, whereas the steps of other high officials give nuances to Hungarian nationalities policies. When Prime Minister István Tisza dropped the program on the eve of the First World War, it was already in a state of hibernation because the governing party had realized that the settlers posed a political liability for them.
Methodological moderators of average outdegree centrality: A meta-analysis of child and adolescent friendship networks
Authors: Neal Jennifer Watling 
Published: March 2024

AbstractEmpirical articles vary considerably in how they measure child and adolescent friendship networks. This meta-analysis examines four methodological moderators of children’s and adolescents’ average outdegree centrality in friendship networks: boundary specification, operational definition of friendship, unlimited vs. fixed choice design, and roster vs. free recall design. Specifically, multi-level random effects models were conducted using 261 average outdegree centrality estimates from 71 English-language peer-reviewed articles and 55 unique datasets. There were no significant differences in average outdegree centrality for child and adolescent friendship networks bounded at the classroom, grade, and school-levels. Using a name generator focused on best/close friends yielded significantly lower average outdegree centrality estimates than using a name generator focused on friends. Fixed choice designs with under 10 nominations were associated with significantly lower estimates of average outdegree centrality while fixed choice designs with 10 or more nominations were associated with significantly higher estimates of average outdegree centrality than unlimited choice designs. Free recall designs were associated with significantly lower estimates of average outdegree centrality than roster designs. Results are discussed within the context of their implications for the future measurement of child and adolescent friendship networks.
The beauty of the body and the ascension: A reclamation and subversion of physical beauty
Authors: Cerbus Laura 
Published: March 2024

AbstractIn the last century, beauty has not often found itself enlisted in struggles for justice. As Alexander Nehemas recounts, beauty's severance from goodness and truth in the modern period renders beauty dangerous, its charm easily wielded as an instrument of oppression in the hands of the powerful. While some scholars have argued for a return to the pre-modern metaphysics that binds beauty to truth and goodness, the abuse of beauty is not simply a modern phenomenon, and its resistance requires more than a pre-modern solution. Beauty is eschatological; thus its abuse points to a failure to order it properly to its eschatological end. This article will argue that the abuse of beauty can be resisted not by spiritualising beauty, but by ordering physical beauty to its eschatological end. This end is most clearly seen in the ascended Christ, with his beautiful body that is human, wounded and hidden.
A bound of the number of weighted blow-ups to compute the minimal log discrepancy for smooth 3-folds
Authors: ISHII SHIHOKO 
Published: March 2024

AbstractWe study a pair consisting of a smooth 3-fold defined over an algebraically closed field and a “general”
${\Bbb R}$
-ideal. We show that the minimal log discrepancy (“mld” for short) of every such a pair is computed by a prime divisor obtained by at most two weighted blow-ups. This bound is regarded as a weighted blow-up version of Mustaţă–Nakamura’s conjecture. We also show that if the mld of such a pair is not less than 1, then it is computed by at most one weighted blow-up. As a consequence, ACC of mld holds for such pairs.
Sequence variations in GATA4 and CITED2 gene among patients with cardiac septation defects from Xinjiang, China
Authors: Imam Renati , Aizezi Maimaitiaili , Yan Fei , Zhu Tao , Zhang Weimin 
Published: March 2024

AbstractStudies have shown that genetic factors play an important role in CHD’s development. The mutations in GATA4 and CITED2 genes result in the failure of the heart to develop normally, thereby leading to septal defects. The present study investigated the underlying molecular aetiology of patients with cardiac septation defects from Xinjiang. We investigated variants of the GATA4 and CITED2 gene coding regions in 172 patients with cardiac septation defects by sequencing. Healthy controls (n = 200) were included. Three heterozygous variations (p.V380M, p.P394T, and p.P407Q) of the GATA4 gene were identified in three patients. p.V380M was discovered in a patient with atrial septal defect. p.P394T was noted in a patient with atrial septal defect. p.V380M and p.P407Q of the GATA4 gene were detected in one patient with ventricular septal defect. A novel homozygous variation (p. Sl92G) of the CITED2 gene was found in one patient with ventricular septal defect. Other patients and healthy individuals were normal. The limited prevalence of genetic variations observed in individuals with cardiac septal defects from Xinjiang provides evidence in favour of the hypothesis that CHD is a polygenic hereditary disorder. It is plausible that mutations in the GATA4 and CITED2 genes could potentially underlie the occurrence of idiopathic CHD in affected patients.
Caridoid crustaceans from the Ballagan Formation (Tournaisian, Lower Carboniferous) of Willie's Hole, Chirnside, Scottish Borders, UK
Authors: CLARK Neil D. L. , ROSS Andrew J. 
Published: March 2024

ABSTRACT
The descriptions of two co-occurring cardioid crustaceans from the Ballagan Formation (Tournaisian, Lower Carboniferous) of Chirnside, Scottish Borders, help to resolve the taxonomy of the genus Tealliocaris. Tealliocaris robusta Peach, 1908 is assigned to Schramocaris to form S. robusta (Peach, 1908) comb. nov. on the basis of morphological characters such as the rugosity and position of the branchial carinae as well as the nature of the pleon, and becomes the earliest representative of this genus in Scotland. A new species of Tealliocaris is also recognised from this locality and is described as T. briggsi sp. nov., based on the smooth carapace, lack of pleonic grooves and the number of spines on the scaphocerite and lateral margin of the anterior carapace. The systematic position of the Pendleian specimens identified by Peach (1908) as ‘Tealliocaris robusta var.’ is finally resolved and described as T. weegie sp. nov.
The impact of floods on plastic pollution
Authors: van Emmerik Tim H. M. 
Published: March 2024

Abstract

Non-Technical Summary
Plastic harms ecosystem health and human livelihood on land, in rivers, and in the sea. To prevent and reduce plastic pollution, we must know how plastics move through the environment. Extreme events, such as floods, bring large amounts of plastic into rivers around the world. This article summarizes how different flood types (excessive rainfall, high river flow, or floods from the sea) flush or deposit plastic pollution, and how this impacts the environment. Furthermore, this paper also discusses how improved resilience to floods is important to prevent and reduce plastic pollution.

Technical Summary
Plastic pollution is ubiquitous in the environment and threatens terrestrial, freshwater, and marine ecosystems. Reducing plastic pollution requires a thorough understanding of its sources, sinks, abundance, and impact. The transport and retention dynamics of plastics are however complex, and assumed to be driven by natural factors, anthropogenic factors, and plastic item characteristics. Current literature shows diverging correlations between river discharge, wind speed, rainfall, and plastic transport. However, floods have been consistently demonstrated to impact plastic transport and dispersal. This paper presents a synthesis of the impact of floods on plastic pollution in the environment. For each specific flood type (fluvial, pluvial, coastal, and flash floods), we identified the driving transport mechanisms from the available literature. This paper introduces the plastic-flood nexus concept, which is the negative feedback loop between floods (mobilizing plastics), and plastic pollution (increasing flood risk through blockages). Moreover, the impact of flood-driven plastic transport was assessed, and it was argued that increasing flood resilience also reduces the impact of floods on plastic pollution. This paper provides a perspective on the importance of floods on global plastic pollution. Increasing flood resilience and breaking the plastic-flood nexus are crucial steps toward reducing environmental plastic pollution.

Social Media Summary
Floods have a large impact on plastic pollution transport, which can be reduced through improved flood resilience
Quantifying changes in the environmental impact of in-crop herbicide use in Saskatchewan, Canada
Authors: Lika Elisabeta , Sutherland Chelsea , Gleim Savannah , Smyth Stuart J. 
Published: March 2024

Abstract
The sustainable management of herbicides is critical to modern agriculture and the environment. This article examines the evolution and environmental implications of herbicide use in Saskatchewan, Canada, agriculture. It quantifies changes in herbicide use and their environmental impacts by analyzing farm-level herbicide use data from 1991 to 1994 and from 2016 to 2019 through the environmental impact quotient. Results confirm significant reductions in both environmental and toxicological impacts of herbicides used, underlining the pivotal shift from tillage-based weed control to herbicide-resistant cropping systems. The environmental impact of the top five herbicides (glufosinate, glyphosate, clethodim, imazamox, and 2,4-D) used from 2016 to 2019 is 65% lower than that for those herbicides (MCPA, 2,4-D, bromoxynil, diclofop-methyl, and trifluralin) used from 1991 to 1994, with a 45% reduction in the active ingredient applied per acre. Despite increased herbicide use due to more crop acres being seeded, the findings highlight a marked improvement in the sustainability of herbicide use, affirming the importance of technological advancements in agriculture. This research contributes valuable insights into long-term trends in herbicide use, offering a practical framework for informed decisions aligning with sustainable agricultural practices as well as reduced biodiversity impacts.
MCL1 inhibition targets Myeloid Derived Suppressors Cells, promotes antitumor immunity and enhances the efficacy of immune checkpoint blockade
Authors: Mukherjee Nabanita , Katsnelson Elizabeth , Brunetti Tonya M. , Michel Kylie , Couts Kasey L. , Lambert Karoline A. , Robinson William A. , McCarter Martin D. , Norris David A. , Tobin Richard P. , Shellman Yiqun G. 
Published: March 2024

AbstractImmune checkpoint inhibitors (ICIs) are now the first-line treatment for patients with advanced melanoma. Despite promising clinical results, many patients fail to respond to these therapies. BH3 mimetics, a novel class of small molecule inhibitors that bind and inhibit anti-apoptotic members of the BCL2 family proteins such as BCL2 or MCL1, have been very successful in treating hematologic malignancies. However, there are limited studies on the immunomodulatory role of the BH3 mimetics. Several factors contribute to ICI resistance including myeloid-derived suppressor cells (MDSCs) that exert immunosuppressive effects through direct and indirect inhibition of antitumor immunity. Thus, targeting MDSCs to enhance antitumor immunity has the potential to enhance the efficacy of ICIs. In this study, we show that the MCL1 inhibitor S64315 reduces melanoma tumor growth in an immune cell-dependent manner in mice. Specifically, S64315 enhances antitumor immunity by reducing MDSC frequency and by promoting the activity of CD8+T cells. Additionally, human MDSCs are 10 times more sensitive to S64315 than cutaneous melanoma lines. Further, we found that a higher expression of MCL1 is associated with poor survival for patients treated with anti-PD-1. Finally, combining S64315 and anti-PD-1 significantly slowed tumor growth compared to either agent alone. Together, this proof-of-concept study demonstrates the potential of combining an MCL1 inhibitor with anti-PD-1 in the treatment of melanoma. It justifies the further development of next generation MCL1 inhibitors to improve efficacy of ICIs in treating malignant melanoma.
GRB2 stabilizes RAD51 at reversed replication forks suppressing genomic instability and innate immunity against cancer
Authors: Ye Zu , Xu Shengfeng , Shi Yin , Cheng Xueqian , Zhang Yuan , Roy Sunetra , Namjoshi Sarita , Longo Michael A. , Link Todd M. , Schlacher Katharina , Peng Guang , Yu Dihua , Wang Bin , Tainer John A. , Ahmed Zamal 
Published: March 2024

AbstractGrowth factor receptor-bound protein 2 (GRB2) is a cytoplasmic adapter for tyrosine kinase signaling and a nuclear adapter for homology-directed-DNA repair. Here we find nuclear GRB2 protects DNA at stalled replication forks from MRE11-mediated degradation in the BRCA2 replication fork protection axis. Mechanistically, GRB2 binds and inhibits RAD51 ATPase activity to stabilize RAD51 on stalled replication forks. In GRB2-depleted cells, PARP inhibitor (PARPi) treatment releases DNA fragments from stalled forks into the cytoplasm that activate the cGAS–STING pathway to trigger pro-inflammatory cytokine production. Moreover in a syngeneic mouse metastatic ovarian cancer model, GRB2 depletion in the context of PARPi treatment reduced tumor burden and enabled high survival consistent with immune suppression of cancer growth. Collective findings unveil GRB2 function and mechanism for fork protection in the BRCA2-RAD51-MRE11 axis and suggest GRB2 as a potential therapeutic target and an enabling predictive biomarker for patient selection for PARPi and immunotherapy combination.
Area-selective atomic layer deposition on 2D monolayer lateral superlattices
Authors: Park Jeongwon , Kwak Seung Jae , Kang Sumin , Oh Saeyoung , Shin Bongki , Noh Gichang , Kim Tae Soo , Kim Changhwan , Park Hyeonbin , Oh Seung Hoon , Kang Woojin , Hur Namwook , Chai Hyun-Jun , Kang Minsoo , Kwon Seongdae , Lee Jaehyun , Lee Yongjoon , Moon Eoram , Shi Chuqiao , Lou Jun , Lee Won Bo , Kwak Joon Young , Yang Heejun , Chung Taek-Mo , Eom Taeyong , Suh Joonki , Han Yimo , Jeong Hu Young , Kim YongJoo , Kang Kibum 
Published: March 2024

AbstractThe advanced patterning process is the basis of integration technology to realize the development of next-generation high-speed, low-power consumption devices. Recently, area-selective atomic layer deposition (AS-ALD), which allows the direct deposition of target materials on the desired area using a deposition barrier, has emerged as an alternative patterning process. However, the AS-ALD process remains challenging to use for the improvement of patterning resolution and selectivity. In this study, we report a superlattice-based AS-ALD (SAS-ALD) process using a two-dimensional (2D) MoS2-MoSe2 lateral superlattice as a pre-defining template. We achieved a minimum half pitch size of a sub-10 nm scale for the resulting AS-ALD on the 2D superlattice template by controlling the duration time of chemical vapor deposition (CVD) precursors. SAS-ALD introduces a mechanism that enables selectivity through the adsorption and diffusion processes of ALD precursors, distinctly different from conventional AS-ALD method. This technique facilitates selective deposition even on small pattern sizes and is compatible with the use of highly reactive precursors like trimethyl aluminum. Moreover, it allows for the selective deposition of a variety of materials, including Al2O3, HfO2, Ru, Te, and Sb2Se3.
A Protein Misfolding Shaking Amplification-based method for the spontaneous generation of hundreds of bona fide prions
Authors: Eraña Hasier , Sampedro-Torres-Quevedo Cristina , Charco Jorge M. , Díaz-Domínguez Carlos M. , Peccati Francesca , San-Juan-Ansoleaga Maitena , Vidal Enric , Gonçalves-Anjo Nuno , Pérez-Castro Miguel A. , González-Miranda Ezequiel , Piñeiro Patricia , Fernández-Veiga Leire , Galarza-Ahumada Josu , Fernández-Muñoz Eva , Perez de Nanclares Guiomar , Telling Glenn , Geijo Mariví , Jiménez-Osés Gonzalo , Castilla Joaquín 
Published: March 2024

AbstractPrion diseases are a group of rapidly progressing neurodegenerative disorders caused by the misfolding of the endogenous prion protein (PrPC) into a pathogenic form (PrPSc). This process, despite being the central event underlying these disorders, remains largely unknown at a molecular level, precluding the prediction of new potential outbreaks or interspecies transmission incidents. In this work, we present a method to generate bona fide recombinant prions de novo, allowing a comprehensive analysis of protein misfolding across a wide range of prion proteins from mammalian species. We study more than 380 different prion proteins from mammals and classify them according to their spontaneous misfolding propensity and their conformational variability. This study aims to address fundamental questions in the prion research field such as defining infectivity determinants, interspecies transmission barriers or the structural influence of specific amino acids and provide invaluable information for future diagnosis and therapy applications.
Quantum many-body simulations on digital quantum computers: State-of-the-art and future challenges
Authors: Fauseweh Benedikt 
Published: March 2024

AbstractSimulating quantum many-body systems is a key application for emerging quantum processors. While analog quantum simulation has already demonstrated quantum advantage, its digital counterpart has recently become the focus of intense research interest due to the availability of devices that aim to realize general-purpose quantum computers. In this perspective, we give a selective overview of the currently pursued approaches, review the advances in digital quantum simulation by comparing non-variational with variational approaches and identify hardware and algorithmic challenges. Based on this review, the question arises: What are the most promising problems that can be tackled with digital quantum simulation? We argue that problems of a qualitative nature are much more suitable for near-term devices then approaches aiming purely for a quantitative accuracy improvement.