bluuebunny/crossref_metadata_2025_split huggingface dataset:
Congruency and its related factors between patients' fall risk perception and nurses' fall risk assessment in acute care hospitals
Authors: Choi Jieun , Lee Sujin , Park Eunjin , Ku Sangha , Kim Sunhwa , Yu Wonhye , Jeong Eunmi , Park Sookhee , Park Yusun , Kim Sung Reul 
Published: February 2024

AbstractIntroductionInpatients need to recognize their fall risk accurately and objectively. Nurses need to assess how patients perceive their fall risk and identify the factors that influence patients' fall risk perception.PurposeThis study aims to explore the congruency between nurses' fall risk assessment and patients' perception of fall risk and identify factors related to the non‐congruency of fall risk.DesignsA descriptive and cross‐sectional design was used. The study enrolled 386 patients who were admitted to an acute care hospital. Six nurses assessed the participants' fall risk. Congruency was classified using the Morse Fall Scale for nurses and the Fall Risk Perception Questionnaire for patients.FindingsThe nurses' fall risk assessments and patients' fall risk perceptions were congruent in 57% of the participants. Underestimation of the patient's risk of falling was associated with gender (women), long hospitalization period, department (orthopedics), low fall efficacy, and history of falls before hospitalization. Overestimation of fall risk was associated with age group, gender (men), department, and a high health literacy score. In the multiple logistic regression, the factors related to the underestimation of fall risk were hospitalization period and department, and the factors related to the overestimation of fall risk were health literacy and department.ConclusionsNurses should consider the patient's perception of fall risk and incorporate it into fall prevention interventions.Clinical RelevanceNurses need to evaluate whether patients perceive the risk of falling consistently. For patients who underestimate or overestimate their fall risk, it may be helpful to consider clinical and fall‐related characteristics together when evaluating their perception of fall risk.
A q$q$ Theory of Internal Capital Markets
Authors: DAI MIN , GIROUD XAVIER , JIANG WEI , WANG NENG 
Published: February 2024

ABSTRACTWe propose a tractable model of dynamic investment, spinoffs, financing, and risk management for a multidivision firm facing costly external finance. Our analysis formalizes the following insights: (i) Within‐firm resource allocation is based not only on divisions' productivity, as in winner‐picking models, but also their risk; (ii) firms may voluntarily spin off productive divisions to increase liquidity; (iii) diversification can reduce firm value in low‐liquidity states, as it increases the spinoff cost and hampers liquidity management; (iv) corporate socialism makes liquidity less valuable; and (v) division investment is determined by the ratio between marginal and marginal value of cash.
Letrozole cotreatment progestin‐primed ovarian stimulation in women undergoing controlled ovarian stimulation for in vitro fertilization
Authors: Wang Xiaoning , Zhang Ying , Diao Honglu , Jiang Shengfang , Zhang Changjun 
Published: February 2024

AbstractAimTo investigate the impact of letrozole cotreatment progestin‐primed ovarian stimulation (PPOS) (Le PPOS) in controlled ovarian stimulation (COS) and the pregnancy outcomes in frozen–thawed embryo transfer cycles.MethodsThis retrospective cohort study included women who underwent in vitro fertilization (IVF)/intracytoplasmic sperm injection (ICSI). A total of 2575 cycles were included (1675 in the Le PPOS group and 900 in the PPOS group). The primary outcome was the clinical pregnancy rates. The secondary outcome was the live birth rates.ResultsIn this study, propensity score matching (PSM) was performed to create a perfect match of 379 patients in each group. After matching, the numbers of oocytes retrieved, mature oocytes, fertilization, and clinical pregnancy rates were more favorable in the Le PPOS group than in the PPOS group (all p < 0.05). The multivariable analysis showed that the clinical pregnancy rate was higher in the Le PPOS than in the PPOS group (odds ratio = 1.46, 95% confidence interval: 1.05–2.04, p = 0.024) after adjusting for potentially confounding factors (age, anti‐Müllerian hormone levels, antral follicular count, the type of embryo transferred, number of transferred embryos, body mass index, and follicular stimulating hormone and estradiol levels on starting day).ConclusionsThis retrospective study with a limited sample size suggests that the Le PPOS protocol might be an alternative to the PPOS protocol in women undergoing COS and could lead to better pregnancy outcomes. The results should be confirmed using a formal randomized controlled trial.
Critical Management Studies: A Critical Review
Authors: Spicer André , Alvesson Mats 
Published: February 2024

AbstractIn this paper, we review the development of critical management studies, point at problems and explore possible developments. We begin by tracing out two previous waves of critical management studies. We then focus on more recent work in critical management studies and identify ten over‐arching themes (Academia, alternatives organizations, control and resistance, discourse, Foucauldian studies, gender, identity, Marxism, post‐colonialism, and psychoanalysis). We argue that CMS has largely relied on one‐dimensional critique which focused on negation. This has made the field increasingly stale, focused on the usual suspects and predictable. We identify a number of problems calling for critique and rethinking. We label these author‐itarianism, obscurantism, formulaic radicalism, usual‐suspectism and empirical light‐touchism.
Non‐invasive measurement of glucocorticoids: The reptile perspective
Authors: Carbajal A. , Serres‐Corral P. , Olvera‐Maneu S. , López‐Béjar M. 
Published: February 2024

AbstractRecent advancements in stress physiology, driven by the relevance of the stress response in animal welfare and conservation, have focused on alternative techniques beyond blood sampling for measuring glucocorticoids (GC). While blood samples have been traditionally used, practical and ethical concerns have spurred exploration into minimally invasive media like saliva, feces, milk, hair, and feathers. This review addresses the dearth of research on reptile endocrinology, offering insights into measuring GC or their metabolites in reptiles through various biological tissues. It underscores the importance of considering temporal dynamics in stress response evaluation and advocates for further exploration of alternative tools to enhance our understanding of reptilian stress responses.
Recovery from deep coma with roving eye movement: A case report and prognostic review
Authors: Madokoro Yuta , Mizuno Masayuki , Inoue Hiroyasu , Oomura Masahiro , Okita Kenji , Matsukawa Noriyuki 
Published: February 2024

AbstractRoving eye movement (RoEM), commonly seen in unconscious patients with significant cortical dysfunction but without apparent brainstem damage, has unclear prognostic significance. We describe a case of presumed hypoglycemic encephalopathy with RoEM, where the patient emerged from a 4‐day coma. While previous reports often associate RoEM cases with poor prognosis, cases with favorable outcomes exist, particularly among young patients or those with reversible conditions. Our findings highlight the variable neurological prognosis of RoEM, suggesting the possibility of improved consciousness and neurological recovery in certain pathologies, thus enhancing our understanding of RoEM's implications.
Deteriorating neurological symptoms of Degos disease despite the treatment with eculizumab and beraprost: A case report with detailed radiological findings
Authors: Nakamura Yamato , Sawamura Masanori , Miyazaki Tatsuhiko , Muramatsu Aya , Suzuki Makoto , Yagi Hiroaki , Hori Akinobu , Katsuyama Yusuke , Yoshida Hidefumi , Kim Kang , Yamada Hiroshi , Takahashi Ryosuke , Harada Kiyoshi 
Published: February 2024

AbstractDegos disease is a rare vasculopathy with a poor prognosis. Here, we report a case of a 17‐year‐old Japanese male with Degos disease who exhibited progressive deterioration of neurological symptoms despite treatment with eculizumab and beraprost. We also report detailed radiological findings including brain magnetic resonance imaging and perfusion computed tomography, and hereby suggest the importance of the perfusion study in detecting early changes associated with Degos disease.
Prediction of liver metastasis and recommended optimal follow‐up nursing in rectal cancer
Authors: Yu Yilin , Wu Junxin , Wu Haixia , Qiu Jianjian , Wu Shiji , Hong Liang , Xu Benhua , Shao Lingdong 
Published: February 2024

AbstractWe aimed to analyze and investigate the clinical factors that influence the occurrence of liver metastasis in locally advanced rectal cancer patients, with an attempt to assist patients in devising the optimal imaging‐based follow‐up nursing. Between June 2011 and May 2021, patients with rectal cancer at our hospital were retrospectively analyzed. A random survival forest model was developed to predict the probability of liver metastasis and provide a practical risk‐based approach to surveillance. The results indicated that age, perineural invasion, and tumor deposit were significant factors associated with the liver metastasis and survival. The liver metastasis risk of the low‐risk group was higher at 6–21 months, with a peak occurrence time in the 15th month. The liver metastasis risk of the high‐risk group was higher at 0–24 months, with a peak occurrence time in the 8th month. In general, our clinical model could predict liver metastasis in rectal cancer patients. It provides a visualization tool that can aid physicians and nurses in making clinical decisions, by detecting the probability of liver metastasis.
Resting cell formation in the marine diatom Thalassiosira pseudonana
Authors: Wang Guangning , Huang Lu , Zhuang Shanshan , Han Fang , Huang Qianqian , Hao Mengyuan , Lin Guifang , Chen Longnan , Shen Biying , Li Feng , Li Xuesong , Chen Changping , Gao Yahui , Mock Thomas , Liang Junrong 
Published: February 2024

Summary

Resting cells represent a survival strategy employed by diatoms to endure prolonged periods of unfavourable conditions. In the oceans, many diatoms sink at the end of their blooming season and therefore need to endure cold and dark conditions in the deeper layers of the water column. How they survive these conditions is largely unknown.

We conducted an integrative analysis encompassing methods from histology, physiology, biochemistry, and genetics to reveal the biological mechanism of resting‐cell formation in the model diatom Thalassiosira pseudonana.

Resting‐cell formation was triggered by a decrease in light and temperature with subsequent catabolism of storage compounds. Resting cells were characterised by an acidic and viscous cytoplasm and altered morphology of the chloroplast ultrastructure.

The formation of resting cells in T. pseudonana is an energy demanding process required for a biophysical alteration of the cytosol and chloroplasts to endure the unfavourable conditions of the deeper ocean as photosynthetic organisms. However, most resting cells (> 90%) germinate upon return to favorable growth conditions.
Fusobacterium nucleatum dysregulates inflammatory cytokines and NLRP3 inflammasomes in oral cells
Authors: Sun Jingzhuo , Feng Susu , Ding Tian , Wang Ting , Du Lingqian , Kang Wenyan , Ge Shaohua 
Published: February 2024

AbstractObjectiveThis study aimed to clarify the difference in Fusobacterium nucleatum (F. nucleatum) induced inflammatory cytokines and nod‐like receptor protein 3 (NLRP3) inflammasomes dysregulation among three periodontal cells.MethodsOral epithelial cells (HIOECs), THP‐1 macrophages, and human gingival fibroblasts (HGFs) were exposed to F. nucleatum with/without adenosine triphosphate (ATP) and nigericin (Nig). Cell morphology was assessed by scanning electron microscopy. qRT‐PCR, protein microarrays, and bioinformatic methods were used to evaluate the cytokines and their complex interplay. NLRP3 inflammasomes activation was detected by western blotting and ELISA.ResultsF. nucleatum adhered to and invaded cells. In HIOECs, F. nucleatum enhanced interleukin (IL)‐1α/1β/6/10/13, TNF‐α, and interferon (IFN)‐γ expression. In THP‐1 macrophages, F. nucleatum up‐regulated IL‐1α/1β/6/10 and TNF‐α levels. In HGFs, F. nucleatum increased IL‐6 levels. F. nucleatum and ATP synergistically boosted IFN‐γ level in THP‐1 macrophages and IL‐13 level in HGFs. IL‐1α/1β/6, and TNF‐α served as epicenters of the inflammatory response. Additionally, F. nucleatum activated NLRP3 inflammasomes in HIOECs, and ATP/Nig boosted the activation. F. nucleatum also triggered NLRP3 inflammasomes in THP‐1 macrophages, but in HGFs, only NLRP3 and caspase‐1 levels were elevated.ConclusionF. nucleatum infiltrated periodontal supporting cells and dysregulated inflammatory cytokines and NLRP3 inflammasomes.
Analyzing arguments in executive veto messages
Authors: Koss Joshua , Ostrander Ian , Sievert Joel 
Published: February 2024

AbstractThe executive veto is one of the most important instruments of presidential power within the legislative arena. Because of constitutional requirements, every regular veto and many pocket vetoes are accompanied by a short letter to Congress from the president describing—often in detail—the reasoning behind the decision to veto. As such, these messages form a unique window into interbranch and partisan conflict over time. While analyses have been conducted on the broad patterns of veto use, questions remain concerning presidential motivations for vetoing as well as how these motivations have evolved over time along with changing political institutions. Using a data set of approximately 2000 unique veto messages from the first in 1792 to the last of President Trump's vetoes in 2021, we examine the content of veto messages to uncover the number and kind of arguments used by presidents when addressing Congress over vetoed legislation. Our analysis uncovers significant variation, with the evolution of arguments within veto messages mirroring broader political trends.
Examining the integrated model of the interpersonal‐psychological theory of suicide and intersectionality theory among Black male adolescents
Authors: Douglas Robyn D. , Alli Jasmine O. , Gaylord‐Harden Noni , Opara Ijeoma , Gilreath Tamika 
Published: February 2024

AbstractIntroductionGuided by Opara et al.'s (2022), Integrated Model of the Interpersonal Psychological Theory of Suicide and Intersectionality Theory, the current study examined contextual stressors experienced disparately by Black youth (racial discrimination, poverty, and community violence) as moderators of the association between individual motivating factors for suicidal thoughts and behaviors (perceived burdensomeness, thwarted belongingness, and hopelessness) and active suicidal ideation.MethodParticipants were 457 Black adolescent boys (mean age = 15.31, SD = 1.26) who completed self‐report surveys.ResultsAs predicted, the association between perceived burdensomeness and active suicidal ideation was significantly moderated by economic stress. In addition, the association between peer belongingness and suicidal ideation was significantly moderated by racial discrimination, but there were no moderating effects for school belongingness. Finally, the association between hopelessness and suicidal ideation was significantly moderated by both racial discrimination and witnessing community violence.ConclusionThese findings highlight the need for research, interventions, and policy work devoted to using integrated approaches of individual and socioeconomically relevant patterns of suicidal thoughts and behaviors to support Black youth exposed to various forms of structural oppression.
The TRAPPIII subunit, Trs85, has a dual role in the trafficking of cellulose synthase complexes in Arabidopsis
Authors: Allen Holly , Zhu Xiaoyu , Li Shundai , Gu Ying 
Published: February 2024

SUMMARYPlant cell walls are essential for defining plant growth and development, providing structural support to the main body and responding to abiotic and biotic cues. Cellulose, the main structural polymer of plant cell walls, is synthesized at the plasma membrane by cellulose synthase complexes (CSCs). The construction and transport of CSCs to and from the plasma membrane is poorly understood but is known to rely on the coordinated activity of cellulose synthase‐interactive protein 1 (CSI1), a key regulator of CSC trafficking. In this study, we found that Trs85, a TRAPPIII complex subunit, interacted with CSI1 in vitro. Using functional genetics and live‐cell imaging, we have shown that trs85‐1 mutants have reduced cellulose content, stimulated CSC delivery, an increased population of static CSCs and deficient clathrin‐mediated endocytosis in the primary cell wall. Overall, our findings suggest that Trs85 has a dual role in the trafficking of CSCs, by negatively regulating the exocytosis and clathrin‐mediated endocytosis of CSCs.
Molecular analysis of the role of polymerase theta in gene targeting in Arabidopsis thaliana
Authors: Kralemann Lejon E. M. , van Tol Niels , Hooykaas Paul J. J. , Tijsterman Marcel 
Published: February 2024

SUMMARYPrecise genetic modification can be achieved via a sequence homology‐mediated process known as gene targeting (GT). Whilst established for genome engineering purposes, the application of GT in plants still suffers from a low efficiency for which an explanation is currently lacking. Recently reported reduced rates of GT in A. thaliana deficient in polymerase theta (Polθ), a core component of theta‐mediated end joining (TMEJ) of DNA breaks, have led to the suggestion of a direct involvement of this enzyme in the homology‐directed process. Here, by monitoring homology‐driven gene conversion in plants with CRISPR reagent and donor sequences pre‐integrated at random sites in the genome (in planta GT), we demonstrate that Polθ action is not required for GT, but instead suppresses the process, likely by promoting the repair of the DNA break by end‐joining. This finding indicates that lack of donor integration explains the previously established reduced GT rates seen upon transformation of Polθ‐deficient plants. Our study additionally provides insight into ectopic gene targeting (EGT), recombination events between donor and target that do not map to the target locus. EGT, which occurs at similar frequencies as “true” GT during transformation, was rare in our in planta GT experiments arguing that EGT predominantly results from target locus recombination with nonintegrated T‐DNA molecules. By describing mechanistic features of GT our study provides directions for the improvement of precise genetic modification of plants.
Influence of a single locking throw on the in vitro holding security of five friction throws
Authors: Wood Chris , Monnet Eric 
Published: February 2024

AbstractObjectiveTo compare the in vitro security of four different friction throws (square, surgeon's, Miller's, and strangle), with and without a locking throw, and a slip knot, on a vascular ligation model.Study designExperimental study.Sample populationNine groups with nine samples per group.MethodsFour throws (square, surgeon's, Miller's, and strangle), with and without a locking throw, and a square throw locked in slip knot fashion, were tested to measure leakage pressure.ResultsThe square and surgeon's throws leaked at a lower pressure than the Miller's and strangle throws (p < .0001). The leakage pressure was below physiologic arterial pressure for the square and the surgeon's throws. After the addition of a locking throw, the five knots leaked at a similar pressure (p = .5233) above physiologic arterial pressure.ConclusionFollowing the addition of a locking throw, all the constructs tested in this study leaked at a similar pressure. The leakage pressure for all knots exceeded physiologic arterial pressures.Clinical significanceAny throw tested may be appropriate for secure vascular ligation if the initial throw is applied correctly.
The use of lateral arthroscopy portals for the management of a fragmented lateral coronoid process in an English Bulldog
Authors: Vernier Timothy H. , Verpaalen Valentine D. , Hinson Whitney D. , Belhorn Stephanie A. , Giglio Robson F. 
Published: February 2024

AbstractObjectiveTo report a case of unilateral lateral coronoid process fragmentation in a dog treated via lateral elbow arthroscopy portals.AnimalA 9‐month old male intact English Bulldog.Study designCase report.MethodsThe dog presented with a history of intermittent right thoracic limb lameness. Orthopedic examination on presentation was unremarkable. Computed tomography of the right thoracic limb was pursued and revealed a mineralized focus along the lateral margin of the lateral coronoid process as well as sclerosis of the medial coronoid process and subtrochlear region of the ulna. Elbow arthroscopy was performed via a lateral approach and revealed chondromalacia of the entire lateral coronoid process. Abrasion arthroplasty of the lateral coronoid process was performed.ResultsComplete resolution of the lameness was achieved within two weeks of surgery. At 6 weeks postoperatively, the dog remained sound and a gradual return to normal activity was recommended. At the final follow up assessment, 5 months after surgery, no abnormalities were found on orthopedic examination and the owners reported excellent limb function with no observable lameness.ConclusionLateral coronoid disease can occur as a rare component of elbow dysplasia in dogs. Abrasion arthroplasty via lateral arthroscopic portals may have resulted in a successful outcome in this case and may form an effective treatment option for lateral coronoid disease in dogs.
Experience of multidisciplinary medical teams on humanistic palliative care in oncology wards: a descriptive qualitative study in Southern China
Authors: Liang Mengna , Liang Jingzhang , Xu Jiefang , Chen Qian , Lu Qiaocong 
Published: February 2024

ObjectivesThis study aimed to explore the experiences of multidisciplinary medical teams in implementing humanistic palliative care within the oncology ward.DesignPurposive and snowball sampling methods were used in this qualitative study, which involved conducting semistructured interviews to gather personal experiences from members of multidisciplinary medical teams providing humanistic palliative care in the oncology ward.SettingThe research was conducted in the oncology ward of a tertiary hospital located in Foshan, China.ParticipantsParticipants included 4 doctors, 12 nurses and 2 medical social workers who form the multidisciplinary medical team responsible for delivering humanistic palliative care to patients with cancer in oncology wards.ResultsPhenomenological qualitative analysis yielded 3 main themes and 9 subthemes. The identified themes were as follows: (1) conceptual change, (2) concrete actions and (3) facilitators and barriers to the implementation of humanistic palliative care.ConclusionThe findings suggest a need for strengthening humanistic consciousness among multidisciplinary palliative care teams working in oncology wards, although there has been a gradual improvement in humanistic care behaviours. Furthermore, facilitators and barriers coexist in the implementation of humanistic palliative care. Efforts should be directed towards refining mechanisms that promote humanistic palliative care, fostering the enthusiasm of healthcare professionals, conducting systematic training to enhance their humanistic care abilities and striving for improvements in the quality of medical services for the benefit of both patients and their families.