bluuebunny/crossref_metadata_2025_split huggingface dataset:
A scenario‐based stochastic programming model for the control or dummy wafers downgrading problem
Authors: Chung Shu‐Hsing , Yang Yi‐Shu 
Published: December 2008

AbstractThe subject of this paper is to study a realistic planning environment in wafer fabrication for the control or dummy (C/D) wafers problem with uncertain demand. The demand of each product is assumed with a geometric Brownian motion and approximated by a finite discrete set of scenarios. A two‐stage stochastic programming model is developed based on scenarios and solved by a deterministic equivalent large linear programming model. The model explicitly considers the objective to minimize the total cost of C/D wafers. A real‐world example is given to illustrate the practicality of a stochastic approach. The results are better in comparison with deterministic linear programming by using expectation instead of stochastic demands. The model improved the performance of control and dummy wafers management and the flexibility of determining the downgrading policy. Copyright © 2008 John Wiley & Sons, Ltd.
On a class of renewal risk model with random income
Authors: Yang Hu , Zhang Zhimin 
Published: December 2008

AbstractIn this paper, we consider a renewal risk process with random premium income based on a Poisson process. Generating function for the discounted penalty function is obtained. We show that the discounted penalty function satisfies a defective renewal equation and the corresponding explicit expression can be obtained via a compound geometric tail. Finally, we consider the Laplace transform of the time to ruin, and derive the closed‐form expression for it when the claims have a discrete Km distribution (i.e. the generating function of the distribution function is a ratio of two polynomials of order m∈ℕ+). Copyright © 2008 John Wiley & Sons, Ltd.
Zur rechnerischen Nachweisführung des Langzeitverhaltens von profilierten Kunststoffrohren unter eingebetteten Bedingungen
Authors: Hu Yifeng , Hoch Albert 
Published: December 2008

AbstractMit Hilfe der Methode der Finiten Elemente wird das Langzeit‐Tragverhalten von eingebetteten, profilierten Kunststoffrohren im Hinblick auf Standsicherheit und Gebrauchstauglichkeit, insbesondere das Profilbeulen bzw. dessen Auswirkung auf die Beulstabilität des Rohres, untersucht. Dabei kommen drei numerische Rechenmodelle (M1, M2 und M3) und der ATV‐Rechenansatz (Stand der Technik, als Referenz) anhand eines ausgewählten Kunststoffrohres mit trapezförmigen Profilen zur Anwendung. Die Aussagekraft der Ringflexibilitätsversuche (eine der Eignungsprüfungen gemäß dem europäischen Normentwurf prEN13476) wird rechnerisch überprüft. Aufgrund der Untersuchungsergebnisse wird ein numerisches Rechenmodell als Alternative für die statische Eignungsprüfung von profilierten Kunststoffrohren unter eingebetteten Bedingungen vorgeschlagen. Auf dieser Basis wird eine Empfehlung für die statische Nachweisführung zur Erteilung allgemeiner bauaufsichtlicher Zulassung für erdverlegte profilierte Kunststoffrohre gemacht.
Mono‐ und biaxiale Spannungszustände in geokunststoffbewehrten Erdbauwerken und ihre Bemessungsrelevanz
Authors: Detert Oliver , Hangen Hartmut 
Published: December 2008

AbstractIn früheren Veröffentlichungen wurde berichtet, dass sich bestimmte Geokunststoffe infolge eines biaxialen Spannungszustands, sowohl kurz‐ als auch langzeitig, deutlich dehnsteifer verhalten als bei einem rein monoaxialen Spannungszustand.Im Hinblick auf die Fragestellung, welche Konsequenzen sich aus der Übertragung eines solchen Materialverhaltens für die Bemessung von geokunststoffbewehrten Erdkörpern ergeben können, werden im Rahmen des vorliegenden Beitrags typische geokunststoffbewehrte Konstruktionen hinsichtlich ihrer Spannungszustände analysiert. Hierzu werden sowohl generelle Überlegungen als auch Ergebnisse aus umfangreichen numerischen Studien, Labor‐ und Feldversuchen dargestellt und diskutiert.Die durchgeführten Untersuchungen führen zu der Erkenntnis, dass rein biaxiale Spannungszustände, wie sie im Labor untersucht wurden, in geokunststoffbewehrten Erdbauwerken selbst unter idealen Randbedingungen nur sehr lokal begrenzt auftreten. Sie besitzen somit keine Relevanz für die Bemessung von geokunststoffbewehrten Erdbauwerken.
Conceptualising dimensions of quality of life in poverty
Authors: Skevington Suzanne M. 
Published: December 2008

AbstractAre existing health‐related quality of life (QoL) measures adequate for use in poverty? Focus groups of development researcher‐practitioners were convened to discuss QoL in the low–middle‐income countries of Ethiopia, Bangladesh, Peru and Thailand. Newly elicited themes were mapped onto the QoL concept consisting of 25 original facets from the WHOQOL‐100, plus 24 additional facets derived from five subsequent WHOQOL modules (49 facets) organized in seven domains. Qualitative themes and importance ratings were used to identify seven novel themes that relate to poverty in these countries. Most are not included in QoL instruments: physical fitness & survival, social status, community relations, family life, work opportunity and environment, fairness and equality, and perception of political institutions. Community relations extended the social domain, and a political rights and freedoms domain was consolidated as a seventh domain. This cross‐national study provides a new conceptual foundation for the international assessment of QoL in poverty. Copyright © 2008 John Wiley & Sons, Ltd.
Polymerase Amplification, Cloning, and Gene Expression of Benzo‐Homologous “yDNA” Base Pairs
Authors: Chelliserrykattil Jijumon , Lu Haige , Lee Alex H. F. , Kool Eric T. 
Published: December 2008

AbstractA widened DNA base‐pair architecture is studied in an effort to explore the possibility of whether new genetic system designs might possess some of the functions of natural DNA. In the “yDNA” system, pairs are homologated by addition of a benzene ring, which yields (in the present study) benzopyrimidines that are correctly paired with purines. Here we report initial tests of ability of the benzopyrimidines yT and yC to store and transfer biochemical and biological information in vitro and in bacterial cells. In vitro primer extension studies with two polymerases showed that the enzymes could insert the correct nucleotides opposite these yDNA bases, but with low selectivity. PCR amplifications with a thermostable polymerase resulted in correct pairings in 15–20 % of the cases, and more successfully when yT or yC were situated within the primers. Segments of DNA containing one or two yDNA bases were then ligated into a plasmid and tested for their ability to successfully lead the expression of an active protein in vivo. Although active at only a fraction of the activity of fully natural DNA, the unnatural bases encoded the correct codon bases in the majority of cases when singly substituted, and yielded functioning green fluorescent protein. Although the activities with native polymerases are modest with these large base pairs, this is the first example of encoding protein in vivo by an unnatural DNA base pair architecture.
Synthesis and Structure–Activity Relationships of Ferrocenyl Tamoxifen Derivatives with Modified Side Chains
Authors: Nguyen Anh , Top Siden , Pigeon Pascal , Vessières Anne , Hillard Elizabeth A. , Plamont Marie‐Aude , Huché Michel , Rigamonti Clara , Jaouen Gérard 
Published: December 2008

AbstractWe report here the synthesis and cell‐proliferation properties of derivatives of the breast cancer drug tamoxifen, in which the O(CH2)2N(CH3)2side chain, responsible for the drug's antiestrogenic properties, has been modified by a ferrocenyl moiety. We recently reported the diphenol compound5, in which this amino chain had been replaced with an acyl‐ferrocenyl (O(CH2)2C(O)[(η5‐C5H4)FeCp]) group, and which showed antiproliferative effects against both the hormone‐dependent MCF‐7 and ‐independent MDA‐MB‐231 breast cancer cell lines. We now report the results of a structure–activity relationship (SAR) study, in which the lateral chain length has been varied, the ketone group has been omitted, and the number of phenol groups has been varied. Compounds1–4, with a side chain lacking the carbonyl function (O(CH2)n[(η5‐C5H4)FeCp],n=1–4) and which show a decreasing affinity for ERα (ER=estrogen receptor) with increasing chain length, act as estrogens on MCF‐7 cells, and mild cytotoxics on PC‐3 prostate cancer cells, with IC50values around 10 μM. The two monophenolic derivatives of2,2 aand2 b, which show a reduced affinity for ERα compared to2, are also estrogenic, but are only slightly cytotoxic. Finally, we have reexamined compound5and discovered that its antiproliferative effect against the MCF‐7 cell line does not arise from antiestrogenicity as we had originally suspected, but by means of a cytotoxic pathway. This compound is also sensitive to the number of phenol groups as cell death is diminished when one of the hydroxyl groups is omitted (5 aand5 b). Molecular modeling studies of the ligand–ERα binding stability are broadly consistent with the experimental binding affinity results for compounds2,2 a,2 b,5,5 a, and5 b. Electrochemical experiments show that1–4,2 a, and2 bare stable to oxidation on the electrochemical timescale, unlike5,5 a, and5 b, and that cytotoxicity is related to less positive phenol oxidation potentials. The SAR study shows that the presence of a ketone group and two phenol groups is necessary for strong receptor binding and cytotoxic effects, and that all compounds are estrogenic, despite the presence of a bulky side chain.
Multifunctional G‐Quadruplex Aptamers and Their Application to Protein Detection
Authors: Li Tao , Shi Lili , Wang Erkang , Dong Shaojun 
Published: December 2008

AbstractTwo significant G‐quadruplex aptamers named AGRO100 and T30695 are identified as multifunctional aptamers that can bind the protein ligands nucleolin or HIV‐1 integrase and hemin. Besides their strong binding to target proteins, both AGRO100 and T30695 exhibit high hemin‐binding affinities comparable to that of the known aptamer (termed PS2M) selected by the in vitro evolution process. Most importantly, their corresponding hemin–DNA complexes reveal excellent peroxidase‐like activities, higher than that of the reported hemin–PS2M DNAzyme. This enables these multifunctional aptamers to be applied to the sensitive detection of proteins, which is demonstrated by applying AGRO100 to the chemiluminescence detection of nucleolin expressed at the surface of HeLa cells. Based on the specific AGRO100–nucleolin interaction, the surface‐expressed nucleolin of HeLa cells is labeled in situ with the hemin–AGRO100 DNAzyme, and then determined in the luminol–H2O2system. Through this approach, the sensitive detection of total nucleolin expressed at the surface of about 6000 HeLa cells is accomplished. Our results suggest that exploiting new functions of existing aptamers will help to extend their potential applications in the biochemical field.
Discrimination of G‐Quadruplexes from Duplex and Single‐Stranded DNAs with Fluorescence and Energy‐Transfer Fluorescence Spectra of Crystal Violet
Authors: Kong De‐Ming , Ma Yong‐E. , Wu Jing , Shen Han‐Xi 
Published: December 2008

AbstractG‐rich nucleic acid sequences with the potential to form G‐quadruplex structures are common in biologically important regions. Most of these sequences are present with their complementary strands, so the development of a sensitive biosensor to distinguish G‐quadruplex and duplex structures and to determine the competitive ability of quadruplex to duplex structures has received a great deal of attention. In this work, the interactions between two triphenylmethane dyes (malachite green (MG) and crystal violet (CV)) and G‐quadruplex, duplex, or single‐stranded DNAs were studied by fluorescence spectroscopy and energy‐transfer fluorescence spectroscopy. Good discrimination between quadruplexes and duplex or single‐stranded DNAs can be achieved by using the fluorescence spectrum of CV or the energy‐transfer fluorescence spectra of CV and MG. In addition, by using energy‐transfer fluorescence titrations of CV with G‐quadruplexes, the binding‐stoichiometry ratios of CV to G‐quadruplexes can be determined. By using the fluorescence titrations of G‐quadruplex–CV complexes with C‐rich complementary strands, the fraction of G‐rich oligonucleotide that engages in G‐quadruplex structures in the presence of the complementary sequence can be measured. This study may provide a simple method for discrimination between quadruplexes and duplex or single‐stranded DNAs and for measuring G‐quadruplex percentages in the presence of the complementary C‐rich sequences.
Chirality in the Absence of Rigid Stereogenic Elements: The Absolute Configuration of Residual Enantiomers of C3‐Symmetric Propellers
Authors: Benincori Tiziana , Marchesi Andrea , Mussini Patrizia Romana , Pilati Tullio , Ponti Alessandro , Rizzo Simona , Sannicolò Francesco 
Published: December 2008

AbstractTwo new tris(aryl)phosphane oxides existing as configurationally stable residual enantiomers have been synthesised and their racemates resolved by semipreparative HPLC on a chiral stationary phase (CSP HPLC). One of them, recognised as a conglomerate, could be resolved by fractional crystallisation at a preparative scale level. In this case, the absolute configuration of the propeller‐shaped molecule was determined by anomalous X‐ray scattering. The problem of the correlative assignment of the absolute configuration to all known C3‐symmetric three‐bladed propeller‐shaped molecules existing as stable residual enantiomers is discussed. The configurational stability of the new chiral phosphane oxides and of the corresponding phosphanes was evaluated by CD signal decay kinetics and dynamic 1H NMR spectroscopy. The racemisation barriers in phosphanes were found about 10 kcal mol−1 lower than those found for the corresponding oxides, though geometry and inter‐ring gearing would be very similar in the two series. Configurational stability of residual tris(aryl)phosphanes was found to be influenced by the electronic availability of the phosphorus centre, as evaluated by electrochemical CV experiments.
Metal Nitride Cluster Fullerene M3N@C80 (M=Y, Sc) Based Dyads: Synthesis, and Electrochemical, Theoretical and Photophysical Studies
Authors: Pinzón Julio R. , Cardona Claudia M. , Herranz Maria Ángeles , Plonska‐Brzezinska Marta E. , Palkar Amit , Athans Andreas J. , Martín Nazario , Rodríguez‐Fortea Antonio , Poblet Josep M. , Bottari Giovanni , Torres Tomás , Gayathri S. Shankara , Guldi Dirk M. , Echegoyen Luis 
Published: December 2008

AbstractThe first pyrrolidine and cyclopropane derivatives of the trimetallic nitride templated (TNT) endohedral metallofullerenes Ih‐Sc3N@C80 and Ih‐Y3N@C80 connected to an electron‐donor unit (i.e., tetrathiafulvalene, phthalocyanine or ferrocene) were successfully prepared by 1,3‐dipolar cycloaddition reactions of azomethine ylides and Bingel–Hirsch‐type reactions. Electrochemical studies confirmed the formation of the [6,6] regioisomers for the Y3N@C80‐based dyads and the [5,6] regioisomers in the case of Sc3N@C80‐based dyads. Similar to other TNT endohedral metallofullerene systems previously synthesized, irreversible reductive behavior was observed for the [6,6]‐Y3N@C80‐based dyads, whereas the [5,6]‐Sc3N@C80‐based dyads exhibited reversible reductive electrochemistry. Density functional calculations were also carried out on these dyads confirming the importance of these structures as electron transfer model systems. Furthermore, photophysical investigations on a ferrocenyl–Sc3N@C80‐fulleropyrrolidine dyad demonstrated the existence of a photoinduced electron‐transfer process that yields a radical ion pair with a lifetime three times longer than that obtained for the analogous C60 dyad.
Synthesis of Diacetylene‐Containing Peptide Building Blocks and Amphiphiles, Their Self‐Assembly and Topochemical Polymerization in Organic Solvents
Authors: Jahnke Eike , Weiss Jan , Neuhaus Sonja , Hoheisel Tobias N. , Frauenrath Holger 
Published: December 2008

AbstractA series of functional iodoacetylenes was prepared and converted into the corresponding diacetylene‐substituted amino acids and peptides via Pd/Cu‐promoted sp–sp carbon cross‐coupling reactions. The unsymmetrically substituted diacetylenes can be incorporated into oligopeptides without a change in the oligopeptide strand's directionality. Thus, a series of oligopeptide‐based, amphiphilic diacetylene model compounds was synthesized, and their self‐organization as well as their UV‐induced topochemical polymerizability was investigated in comparison to related polymer‐substituted macromonomers. Solution‐phase IR spectroscopy, gelation experiments, and UV spectroscopy helped to confirm that a minimum of five N‐H⋅⋅⋅OC hydrogen‐bonding sites was required in order to obtain reliable aggregation into stable β‐sheet‐type secondary structures in organic solvents. Furthermore, the non‐equidistant spacing of these hydrogen‐bonding sites was proven to invariably lead to β‐sheets with a parallel β‐strand orientation, and the characteristic IR‐spectroscopic signatures of the latter in organic solution was identified. Scanning force micrographs of the organogels revealed that compounds with six hydrogen‐bonding sites gave rise to high aspect ratio nanoscopic fibrils with helical superstructures but, in contrast to the related macromonomers, did not lead to uniform supramolecular polymers. The UV‐induced topochemical polymerization within the β‐sheet aggregates was successful, proving parallel β‐strand orientation and highlighting the effect of the number and pattern of N‐H⋅⋅⋅OC hydrogen‐bonding sites as well as the hydrophobic residue in the molecular structure on the formation of higher structures and reactivity.
Total Synthesis of (+)‐Neomarinone
Authors: Peña‐López Miguel , Martínez M. Montserrat , Sarandeses Luis A. , Pérez Sestelo José 
Published: December 2008

AbstractThe first total synthesis of (+)‐neomarinone has been achieved by following a concise and convergent route using methyl (R)‐lactate and (R)‐3‐methylcyclohexanone as chiral building blocks. Key steps of the synthesis are the stereocontrolled formation of the two quaternary stereocenters by diastereoselective 1,4‐conjugate addition and enolate alkylation reactions, and the construction of the furanonaphthoquinone skeleton by regioselective Diels–Alder reaction between a 1,3‐bis(trimethylsilyloxy)‐1,3‐diene and a bromoquinone. The synthesis proves the relative and absolute stereochemistry of natural neomarinone.
ChemInform Abstract: Polymorphism in PbBiOXO4 Compounds (X: V, P, As). Part 1. Crystal Structures of α‐ and β‐PbBiOVO4.
Authors: Labidi Olfa , Roussel Pascal , Porcher Florence , Drache Michel , Vannier Rose‐Noelle , Wignacourt Jean‐Pierre 
Published: December 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Chiral N‐Phosphonyl Imine Chemistry: Asymmetric Addition of Ketone‐Derived Enolates for the Synthesis of β‐Amino Ketones.
Authors: Han Jianlin , Ai Teng , Li Guigen 
Published: December 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis of New Aminophosphine Complexes and Their Catalytic Activities in C—C Coupling Reactions.
Authors: Biricik Nermin , Durap Feyyaz , Kayan Cezmi , Guemguem Bahattin , Guerbuez Nevin , Oezdemir Ismail , Ang Wee Han , Fei Zhaofu , Scopelliti Rosario 
Published: December 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Vanadium Schiff Base Complexes: Chemistry, Properties, and Possible Therapeutic Applications
Authors: Pessoa Joao Costa , Cavaco I. , Correia I. , Tomaz I. , Adao P. , Vale I. , Ribeiro V. , Castro M. M. C. A. , Geraldes C. C. F. G. 
Published: December 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Design of Gold Nanoparticle‐Based Colorimetric Biosensing Assays
Authors: Zhao Weian , Brook Michael A. , Li Yingfu 
Published: December 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Prevalence and prediction of re‐experiencing and avoidance after elective surgical abortion: a prospective study
Authors: van Emmerik Arnold A. P. , Kamphuis Jan H. , Emmelkamp Paul M. G. 
Published: December 2008

AbstractObjective: This study investigated short‐term re‐experiencing and avoidance after elective surgical abortion. In addition, it was prospectively investigated whether peritraumatic dissociation and pre‐abortion dissociative tendencies and alexithymia predict re‐experiencing and avoidance. Method: In a prospective observational design, Dutch‐speaking women presenting for first trimester elective surgical abortion completed self‐report measures for dissociative tendency and alexithymia. Peritraumatic dissociation was measured immediately post‐abortion. Re‐experiencing and avoidance were measured 2 months post‐abortion. Results: Participants reported moderately elevated levels of re‐experiencing and avoidance that exceeded a clinical cut‐off point for 19.4% of the participants. Peritraumatic dissociation predicted intrusion and avoidance at 2 months. In addition, avoidance was predicted by the alexithymic aspect of difficulty describing feelings. Conclusions: Re‐experiencing and avoidance after elective surgical abortion represent a significant clinical problem that is predicted by peritraumatic dissociation and alexithymia. Psychological screening and intervention might be a useful adjunct to elective abortion procedures. Copyright © 2008 John Wiley & Sons, Ltd.
Synthesis and Photocatalytic Activity of Zn2GeO4 Nanorods for the Degradation of Organic Pollutants in Water
Authors: Huang Jianhui , Ding Kaining , Hou Yidong , Wang Xinchen , Fu Xianzhi 
Published: December 2008

AbstractZn2GeO4 nanorods were prepared by a surfactant‐assisted hydrothermal method and used as photocatalysts for the decomposition of organic pollutants in water. The physicochemical properties of the Zn2GeO4 photocatalysts were characterized by several techniques, and their photocatalytic activity was evaluated by the decomposition of methyl orange, salicylic acid, and 4‐chlorophenol in aqueous solution. The results revealed that the Zn2GeO4 nanorods have a much higher photocatalytic activity for decomposing organic pollutants in aqueous solution than both Zn2GeO4 prepared by a conventional solid‐state reaction and widely used TiO2 (Degussa P25). There is no obvious deactivation of Zn2GeO4 nanorods in the photocatalytic reactions. The intermediates of the photocatalytic reactions were monitored by LC‐MS, and possible photocatalytic reaction pathways as to how Zn2GeO4 nanorods degrade organic dyes were proposed.