bluuebunny/crossref_metadata_2025_split huggingface dataset:
Low Cerebral Blood Volume Index, Thrombectomy, and Prior Stroke Are Independently Associated With Hemorrhagic Transformation in Medium‐Vessel Occlusion Ischemic Stroke
Authors: Yedavalli Vivek S. , Koneru Manisha , Hoseinyazdi Meisam , Marsh Elisabeth B. , Llinas Rafael H. , Urrutia Victor , Leigh Richard , Gonzalez Luis Fernando , Xu Risheng , Caplan Justin , Huang Judy , Lu Hanzhang , Wintermark Max , Dmytriw Adam A. , Guenego Adrien , Albers Gregory W. , Luna Licia , Heit Jeremy J. , Nael Kambiz , Hillis Argye E. 
Published: March 2024

Background
Hemorrhagic transformation (HT) is a major complication in patients with acute ischemic stroke (AIS) treated with endovascular thrombectomy. However, HT in patients with AIS due to medium‐vessel occlusions has still not been well researched. In large‐vessel occlusions, collateral status is an important determinant of postprocedural HT, and the cerebral blood volume (CBV) index is a reliable surrogate of collateral status. The aim of our study is to identify an optimal CBV index threshold associated with HT in patients with AIS due to medium‐vessel occlusion and evaluate additional parameters that are independently associated with HT in this group.

Methods

This retrospective analysis of our prospectively collected database from 2 comprehensive stroke centers consisted of patients presenting with AIS due to medium‐vessel occlusion from 2019 to 2023. The primary outcome was the presence of HT on follow‐up imaging. Optimal CBV index cutoff for HT was derived from a univariate logistic regression analysis. Multivariable logistic regression analysis for HT was derived from the dichotomized CBV index and other covariates. The receiver operator characteristic curve yielded area under the curve. Statistical significance was
P

≤
$ \le $

0.05.

Results

Of 111 patients (median age, 70 years; 43.2% women) included, 26 (23.4%) patients had HT. The optimal CBV index cutoff was 0.7. From multivariable regression analysis, significant variables included prior stroke (adjusted odds ratio [aOR], 7.18 [95% CI, 1.60–32.16];
P
= 0.01), endovascular thrombectomy attempt (aOR, 7.86 [95% CI, 1.78–34.68];
P
= 0.01), and CBV index (

≤
$ \le $

0.7; aOR, 4.23 [95% CI, 1.02–17.59];
P
= 0.04). The area under the curve was 0.82 (95% CI, 0.69–0.91).

Conclusion

A CBV index

≤
$ \le $

0.7 was independently associated with HT in patients with AIS due to medium‐vessel occlusion. Endovascular thrombectomy attempt and prior stroke history were also independently associated with HT in this population.
Can prediction error explain predictability effects on the N1 during picture-word verification?
Authors: Taylor Jack E. , Rousselet Guillaume A. , Sereno Sara C. 
Published: March 2024

Abstract
Do early effects of predictability in visual word recognition reflect prediction error? Electrophysiological research investigating word processing has demonstrated predictability effects in the N1, or first negative component of the event-related potential (ERP). However, findings regarding the magnitude of effects and potential interactions of predictability with lexical variables have been inconsistent. Moreover, past studies have typically used categorical designs with relatively small samples and relied on by-participant analyses. Nevertheless, reports have generally shown that predicted words elicit less negative-going (i.e., lower amplitude) N1s, a pattern consistent with a simple predictive coding account. In our preregistered study, we tested this account via the interaction between prediction magnitude and certainty. A picture-word verification paradigm was implemented in which pictures were followed by tightly matched picture-congruent or picture-incongruent written nouns. The predictability of target (picture-congruent) nouns was manipulated continuously based on norms of association between a picture and its name. ERPs from 68 participants revealed a pattern of effects opposite to that expected under a simple predictive coding framework.
The Effects of Virtual Reality Used in Healthcare Education on Cybersickness and Sense of Presence: A Systematic Review
Authors: Erbaş Atiye , Akyüz Elif , Ergöl Şule 
Published: March 2024

Abstract
The purpose of this systematic review was to present the current state of the science related to healthcare students’ outcomes associated with virtual reality effects on cybersickness and sense of presence. Results of the database searches of MEDLINE/PubMed, Scopus, ISI Web of Science, CINAHL, and Cochrane identified 101 articles. Seven articles were isolated for inclusion in this review. The primary search terms were “healthcare students,” “virtual reality,” “cybersickness,” and “sense of presence.” The studies were published between 2016 and 2020 and were conducted in Israel, the United States, the United Kingdom, Singapore, Belgium, and Brazil. The research design was quasi-experimental in six studies and experimental design in one study. Interventions were mostly carried out with nursing, medical, and dental students. Three studies used immersive virtual reality simulation with a head-mounted display, while the others used non-immersive three-dimensional visuals. According to the results, students perceived a high sense of presence and a low level of cybersickness in virtual reality simulations. There is limited robust research exploring healthcare students’ outcomes related to virtual reality on cybersickness and sense of presence.
On Middle Persian Interference in Early Arabic Prose
Authors: D’Anna Luca , Benkato Adam 
Published: March 2024

Abstract
This paper discusses agreement patterns in Kalīla wa-Dimna, a collection of animal fables translated from Middle Persian to Arabic in the 8th century CE by Ibn al-Muqaffaʿ and considered one of the masterpieces of early Arabic prose. It advances the hypothesis that the text bears traces of interference from the L1 of its translator, Middle Persian. Kalīla wa-Dimna features agreement patterns unattested in any other described variety of Arabic. The paper provides an introduction to the complex textual history of Kalīla wa-Dimna, followed by a detailed analysis of the agreement patterns emerging from the text. A survey of agreement in both Arabic (in its written and spoken varieties) and Middle Persian then highlights the main differences between the two systems, followed by a discussion of the possible interference that resulted in Ibn al-Muqaffaʿ’s reinterpretation of the Arabic system as based on animacy.
Translating the Self in Medieval European Romance: Narration and Emotion in Partonopeu de Blois, Partonopier und Meliur and Partonope of Blois
Authors: Kaempfer Lucie 
Published: March 2024

Abstract
This article approaches the question of selfhood by reading the opening passage of the Old French romance Partonopeu de Blois alongside its translations in different Northern European languages: the thirteenth-century Middle High German Partonopier und Meliur by Konrad von Würzburg and the fifteenth-century Middle English Partonope of Blois. Both translations bring interiority and subjectivity to the passage by adding direct speech and access to the character’s thoughts and motivations. In allowing the protagonist to respond to and rationalise his own emotions, the translators add a layer of self-awareness to their characterisation, thus producing a narrated self that was lacking in the original. This article demonstrates the great potential of comparative analysis in the study of medieval emotion and self. The different linguistic versions of the same passage here illuminate one another, highlighting different narrative techniques in the construction of literary selfhood. While the objective, exterior style of narration in the Old French passage constructs a helpless character, lacking in self-possession, the later German and English translations display a different narrative strategy that reveals their character’s decision-making process, and thus make him into a self-reflecting agent.
Locking in Human Rights: An Exploration of the Barriers to echr Withdrawal
Authors: Cowell Frederick 
Published: March 2024

Abstract
The possibility of the United Kingdom being able to withdraw from the European Convention on Human Rights (echr or Convention) by way of a denunciation under Article 58(1) of the Convention is complicated by a number of domestic constitutional factors and other international legal obligations. This paper explains how, collectively, these constitute a form of ‘lock in’ to the echr. This makes any future UK withdrawal from the echr highly difficult and liable to cause a range of collateral consequences on the international and domestic legal planes.
Increased Extreme Precipitation in May over Southwestern Xinjiang in Relation to Eurasian Snow Cover in Recent Years
Authors: Chen Ping , Yao Junqiang , Mao Weiyi , Ma Liyun , Chen Jing , Dilinuer Tuoliewubieke , Li Shujuan 
Published: March 2024

Abstract
In this study, the interdecadal variations of extreme precipitation in May over southwestern Xinjiang (SWX) and related mechanisms were investigated. The extreme precipitation in May over SWX exhibited a decadal shift in the 1990s (negative phase during 1970–86 and positive phase during 2003–18). The decadal shift corresponded to strengthened moist airflow from the Indian Ocean and an anomalous cyclone over SWX during 2003–18. It is found that the interdecadal change of the wave trains in Eurasia might account for the differences in atmospheric circulation between the above two periods. Further analyses reveal that spring snow cover over Eurasia is closely linked to extreme precipitation over SWX during 2003–18. Increased snow cover in western Europe (WE) from February to March is accompanied by more snowmelt. This resulted in less local snow cover and lower albedo, leading to warm temperatures over WE in May. The changes in temperatures increase the local 1000–500-hPa thickness over WE. These factors provide favorable conditions for the enhancement of the Eurasian wave trains, which significantly influence extreme precipitation over SWX. On the other hand, corresponding to decreased albedo caused by the reduction of snow cover in northern Eurasia (NE) in May, anomalous surface warming occurs over NE. The anomalous warming results in positive geopotential height anomalies that intensify the meridional geopotential height gradient over Eurasia and cause an acceleration of the westerly jet in May. Anomalous upper-level divergence in SWX induced by the enhanced westerly jet provides a favorable dynamical condition for increased extreme precipitation.
Guidelines of the International Headache Society for controlled trials of pharmacological preventive treatment for persistent post-traumatic headache attributed to mild traumatic brain injury
Authors: Ashina Håkan , Diener Hans-Christoph , Tassorelli Cristina , Scher Ann I. , Lipton Richard B. , Pozo-Rosich Patricia , Sinclair Alexandra J. , Chong Catherine D. , Finkel Alan G. , Ashina Messoud , Schwedt Todd J. , Dodick David W. , Terwindt Gisela M. 
Published: March 2024

Background Persistent headache attributed to traumatic injury to the head is divided into two subtypes, one attributed to moderate or severe traumatic injury and another attributed to mild traumatic injury (i.e., concussion). The latter is much more prevalent, in part because more than 90% of cases with traumatic brain injury are classified as mild. The pathophysiology of persistent post-traumatic headache is poorly understood and the underlying mechanisms are likely multifactorial. There is currently no approved treatment specifically for persistent post-traumatic headache, and management strategies rely on medications used for migraine or tension-type headache. Therefore, high-quality trials are urgently needed to support clinical decision-making and optimize management strategies. International guidelines can facilitate appropriate trial design and ensure the acquisition of high-quality data evaluating the efficacy, tolerability, and safety of available and novel pharmacological therapies for the preventive treatment of persistent post-traumatic headache. Methods The development of this guideline was based on a literature review of available studies in MEDLINE, Embase, and the Cochrane Central Register of Controlled Trials, along with a review of previously published guidelines for controlled trials of preventive treatment for episodic and chronic migraine. The identified literature was critically appraised, and due to the scarcity of scientific evidence, recommendations were primarily based on the consensus of experts in the field. Objective To provide guidelines for designing state-of-the-art controlled clinical trials aimed at evaluating the effectiveness of preventive treatments for persistent post-traumatic headache attributed to mild traumatic brain injury.
Robotic-assisted total knee arthroplasty results in decreased incidence of anterior femoral notching compared to posterior referenced instrumented total knee arthroplasty
Authors: Li MingYang , Zhang YongTao , Shao ZhenShuai , Zhu HaoXiang 
Published: March 2024

Objective Periprosthetic fracture (PPF) is an uncommon but devastating complication after total knee arthroplasty (TKA). Anterior femoral notching (AFN) is one of a perioperative risk factor for PPF. The main purpose of this study was to compare between the rates of anterior femoral notching (AFN) and supracondylar periprosthetic femoral fracture (sPPF) of manual TKA and robotic arm-assisted TKA (RATKA). Meanwhile, blood loss, transfusion rates, inflammatory responses, complications, early clinical and radiological outcomes were also assessed. Methods This retrospective study included 330 patients (133 RATKA and 197 manual TKA). Differences in risks of inflammatory, blood loss, complications (periprosthetic fracture and periprosthetic joint infection), pre-operative and post-operative distal lateral femoral angle (LDFA), distal femoral width (DFW), prosthesis-distal femoral width (PDFW) ratio, AFN, femoral component flexion angle (FCFA), peri-operative and post-operative functional outcomes between the RATKA and manual TKA groups were compared. Results The operation time and postoperative CRP level in the RATKA group was significantly longer and higher than that in the manual TKA group ( p < .001). However, there was no significant difference in postoperative WBC level ( p = .217), hemoglobin loss ( p = .362), postoperative drainage ( p = .836), and periprosthetic fracture ( p = 1.000). There was no significant difference in LDFA ( p > .05), DFW( p = .834), PDFW ratio ( p = .089) and FCFA ( p = .315) between the two groups, but the rate of AFN in the RATKA group was significantly lower than that in the manual TKA group ( p < .05). There was no significant difference in ROM between the two groups on POD3, POD 90 and 1 year ( p < .05), but the FJS-12 score in the RATKA group was higher than that in the manual TKA group on 1 year ( p = .001). Conclusion Robotic-assisted total knee arthroplasty can decrease the incidence of anterior femoral notching compared to posterior referenced instrumented total knee arthroplasty.
Increasing incidence of contact-lens-related Acanthamoeba keratitis in a tertiary ophthalmology department in an Italian population
Authors: Messina Marco , Tucci Davide , Mocini Stefano , Marruso Virginia , Crotti Silvia , Said Dalia , Dua Harminder Singh , Cagini Carlo 
Published: March 2024

Purpose The purpose of this paper is to report the increasing incidence of contact-lens related Acanthamoeba keratitis (AK) in a tertiary ophthalmology department in Umbria, central Italy. Methods Observational and retrospective case series were carried out. A total of nine eyes with a diagnosis of AK were examined. All patients underwent a full slit lamp examination, in vivo confocal microscopy (IVCM) and corneal scraping. The IVCM was repeated at one and two-week and at one, three and six-month intervals. Samples of domestic tap water were also examined for PCR analysis. Patients were treated with levofloxacin0,5%, Polyhexamethylene biguanide 0.02%, and Propamidine Isetionate0,1%. Results All patients were contact lens wearers. The average patient age was 27.75 (range 18–45), with three men and five women. The main clinical features were ciliary congestion, diffuse epitheliopathy with punctuated keratitis, multiple, small sub-epithelial, greyish, corneal infiltrates with epithelial defect, pseudodendritic corneal lesions, perineural infiltrates, corneal stromal cellularity, and stromal infiltrates. IVCM was indicative of Acanthamoeba in seven out of the nine eyes. All the positive IVCM images were section images showing double walled, bright-spot cysts with a clear chain-like arrangement of five or more cysts identified in three of the patients. PCR analysis of the water was negative in all cases. Conclusion Although PCR is the most common method used, the increased incidence of AK could mainly be related to a proper IVCM interpretation. A broad-spectrum antibiotic, such as levofloxacin might play a role in the early treatment of AK reducing the virulence of the amoeba.
Discrimination and health: A cross-sectional study comparing Muslims with other-religious
Authors: Ishaq Bushra , Diaz Esperanza , Østby Lars 
Published: March 2024

Aims: The aim of this study is to report perceived discrimination among Muslims living in Norway and to address and compare associations between perceived discrimination and health among Muslims with an immigrant background and other-religious with an immigrant background. Method: A representative sample of individuals with an immigrant background in Norway was used in a cross-sectional study design that included 5484 respondents aged 16 to 74 years. The respondents were sub-grouped after religious affiliation, and as immigrants and Norwegian-born. This sample is from ‘The Survey on living conditions among persons with an immigrant background 2016’, conducted by Statistics Norway. Multivariate logistic regression analyses were conducted to investigate the relationship between perceived discrimination and self-rated health and between perceived discrimination and mental health problems. Results: Our findings show that Muslims with an immigrant background are more likely to report perceived discrimination than non-Muslims with an immigrant background. Perceived discrimination was associated with poor self-rated health and mental health problems among immigrant Muslims and Norwegian-born Muslims. Among other-religious with an immigrant background, perceived discrimination had an inverse relationship with mental health problems among immigrants, while an association between perceived discrimination and poor self-rated health was found among Norwegian-born. Conclusions: Our findings suggest that perceived discrimination does play a role in health among minorities with an immigrant background in Norway, regardless of religion. However, the association between perceived discrimination and poor health seems to be stronger among Muslims, especially Norwegian-born Muslims.
Associations Between Health Behaviors, Gastrointestinal Symptoms, and Gut Microbiota in a Cross-Sectional Sample of Cancer Survivors: Secondary Analysis from the Chemo-Gut Study
Authors: Deleemans Julie M. , Chleilat Faye , Reimer Raylene A. , Lawal Oluwaseyi A. , Baydoun Mohamad , Piedalue Katherine-Ann , Lowry Dana E. , Carlson Linda E. 
Published: March 2024

Background: Health behaviors, such as diet and exercise, are actions individuals take that can potentially impact gastrointestinal (GI) symptoms and the gut microbiota. Little is known about how health behaviors impact GI symptoms and the gut microbiota after anti-cancer therapies. Methods: This is a secondary analysis of a cross-sectional study that investigated relationships between GI symptoms, gut microbiota, and patient-reported outcomes in adult cancer survivors. Gut microbiota was assessed from stool samples using 16 S rRNA gene sequencing. GI symptoms and health behaviors were measured via self-report. Descriptive statistics, multiple regression, and correlation analyses are reported. Results: A total of 334 cancer survivors participated, and a subsample of 17 provided stool samples. Most survivors rated their diet as moderately healthy (55.7%) and reported engaging in low intensity exercise (53.9%) for ≤5 h/week (69.1%). Antibiotic use was associated with more belly pain, constipation, and diarrhea ( P < .05). Survivors consuming a healthier diet had fewer symptoms of belly pain ( P = .03), gas/bloating ( P = .01), while higher protein consumption was associated with less belly pain ( P = .03). Better diet health was positively correlated with Lachnospiraceae abundance, and negatively with Bacteroides abundance ( P < .05). Greater exercise frequency positively correlated with abundance of Lachnospiraceae, Faecalibacterium, Bacteroides, Anaerostipes, Alistipes, and Subdoligranulum ( P < .05). Conclusion: Results provide evidence for associations between antibiotic use, probiotic use, dietary health behaviors, and GI symptoms. Diet and exercise behaviors are related to certain types of bacteria, but the direction of causality is unknown. Dietary-based interventions may be optimally suited to address survivors’ GI symptoms by influencing the gut microbiota. Larger trials are needed.
Online health information behaviour and its association with statin adherence in patients with high cardiovascular risk: A prospective cohort study
Authors: Lim Hooi Min , Ng Chirk Jenn , Abdullah Adina , Danee Mahmoud , Raubenheimer Jacques , Dunn Adam G. 
Published: March 2024

Objective Statins are effective for preventing cardiovascular disease. However, many patients decide not to take statins because of negative influences, such as online misinformation. Online health information may affect decisions on medication adherence, but measuring it is challenging. This study aimed to examine the associations between online health information behaviour and statin adherence in patients with high cardiovascular risk. Methods A prospective cohort study involving 233 patients with high cardiovascular risk was conducted at a primary care clinic in Malaysia. Participants used a digital information diary tool to record online health information they encountered for 2 months and completed a questionnaire about statin necessity, concerns and adherence at the end of the observation period. Data were analysed using structural equation modelling. Results The results showed that 55.8% (130 of 233 patients) encountered online health information. Patients who actively sought online health information (91 of 233 patients) had higher concerns about statin use ( β = 0.323, p = 0.023). Participants with higher concern about statin use were also more likely to be non-adherent ( β = -0.337, p < 0.001). Patients who actively sought online health information were more likely to have lower statin adherence, mediated by higher concerns about statin use (indirect effect, β = -0.109, p = 0.048). Conclusions Our results suggest that patients with higher levels of concern about statins may be actively seeking online information about statins, and their concerns might influence how they search, what they find, and the potential to encounter misinformation. Our study highlights the importance of addressing patients’ concerns about medications to improve adherence.