bluuebunny/crossref_metadata_2025_split huggingface dataset:
Problematic pornography use across countries, genders, and sexual orientations: Insights from the International Sex Survey and comparison of different assessment tools
Authors: Bőthe Beáta , Nagy Léna , Koós Mónika , Demetrovics Zsolt , Potenza Marc N. ,   International Sex Survey Consortium, Kraus Shane W. 
Published: February 2024

AbstractBackground and aimsProblematic pornography use (PPU) is a common manifestation of the newly introduced Compulsive Sexual Behavior Disorder diagnosis in the 11th edition of the International Statistical Classification of Diseases and Related Health Problems. Although cultural, gender‐ and sexual orientation‐related differences in sexual behaviors are well documented, there is a relative absence of data on PPU outside Western countries and among women as well as gender‐ and sexually‐diverse individuals. We addressed these gaps by (a) validating the long and short versions of the Problematic Pornography Consumption Scale (PPCS and PPCS‐6, respectively) and the Brief Pornography Screen (BPS) and (b) measuring PPU risk across diverse populations.MethodsUsing data from the pre‐registered International Sex Survey [n = 82 243; mean age (Mage) = 32.4 years, standard deviation = 12.5], a study across 42 countries from five continents, we evaluated the psychometric properties (i.e. factor structure, measurement invariance, and reliability) of the PPCS, PPCS‐6, and BPS and examined their associations with relevant correlates (e.g. treatment‐seeking). We also compared PPU risk among diverse groups (e.g. three genders).ResultsThe PPCS, PPCS‐6, and BPS demonstrated excellent psychometric properties [for example, comparative fit index = 0.985, Tucker–Lewis Index = 0.981, root mean square error of approximation = 0.060 (90% confidence interval = 0.059–0.060)] in the confirmatory factor analysis, with all PPCS’ inter‐factor correlations positive and strong (rs = 0.72–0.96). A total of 3.2% of participants were at risk of experiencing PPU (PPU+) based on the PPCS, with significant country‐ and gender‐based differences (e.g. men reported the highest levels of PPU). No sexual orientation‐based differences were observed. Only 4–10% of individuals in the PPU+ group had ever sought treatment for PPU, while an additional 21–37% wanted to, but did not do so for specific reasons (e.g. unaffordability).ConclusionsThis study validated three measures to assess the severity of problematic pornography use across languages, countries, genders, and sexual orientations in 26 languages: the Problematic Pornography Consumption Scale (PPCS, and PPCS‐6, respectively), and the Brief Pornography Screen (BPS). The problematic pornography use risk is estimated to be 3.2–16.6% of the population of 42 countries, and varies among different groups (e.g. genders) and based on the measure used.
Chinese‐Australian carers' perceived needs and preferences in planning to embed an iSupport for Dementia program in aged care services
Authors: Yu Ying , Xiao Lily , Cheng Ada , Wang Ivan , Chiu Kam , Chan Eliza , Xie Candy , Zhou Yunrui , Zhuang Zoey , Wang Jing 
Published: February 2024

AbstractObjectiveTo assess Chinese‐Australian carers' needs and preferences through co‐design strategies with stakeholders to embed an evidence‐based iSupport for Dementia program into routine community aged care services in Chinese ethno‐specific aged care organisations.MethodsA cross‐sectional survey was conducted from July to August 2022 in three Chinese ethno‐specific aged care organisations in Australia. We applied a univariate analysis to test variables associated with carers' needs and preferences when embedding the iSupport for Dementia program into routine practice among community aged care services.ResultsA total of 101 carers completed the survey. Most carers in our study preferred the iSupport program to be provided in their first language, have a program facilitator to lead the program and would like to interact with peers in the program. Most carers indicated that they are willing to pay for the iSupport program using the budget allocated to their home care package. Younger carers (younger than 65 years), and adult children's carers are more likely to use the web‐based iSupport manual and invite their family members to the program compared to those older than 65 years. Other demographic characteristics had no significant association with their needs and preferences.ConclusionsChinese‐Australian carers' perceived needs and preferences in this study will inform the implementation of a culturally tailored iSupport program to be embedded in community aged care services provided by Chinese ethno‐specific aged care organisations. Findings will also inform culturally and linguistically congruent iSupport programs for carers from other culturally and linguistically diverse communities in Australia.
Face and content validity of a mobile delirium screening tool adapted for use in the medical setting (eDIS‐MED): Welcome to the machine
Authors: Eeles Eamonn , Tronstad Oystein , Teodorczuk Andrew , Flaws Dylan , Fraser John F , Dissanayaka Nadeeka 
Published: February 2024

AbstractObjectivesFollowing a user‐centred redesign and refinement process of an electronic delirium screening tool (eDIS‐MED), further accuracy assessment was performed prior to anticipated testing in the clinical setting.MethodsContent validity of each of the existing questions was evaluated by an expert group in the domains of clarity, relevance and importance. Questions with a Content Validity Index (CVI) <0.80 were reviewed by the development group for potential revision. Items with CVI <0.70 were discarded. Next, face validity of the entirety of the tests was conducted and readability measured.ResultsA panel of five clinical experts evaluated the test battery comprising eDIS‐MED. The content validity process endorsed 61 items. The overall scale CVI was 0.92. Eighty‐eight per cent of the responses with regard to question relevancy, usefulness and appropriateness were positive. The questions were deemed fifth grade level and very easy to read.ConclusionsA revised electronic screening tool was shown to be accurate according to an expert group. A clinical validation study is planned.
Perinatal outcomes following fetoscopic laser surgery for early twin‐to‐twin transfusion syndrome: Systematic review and meta‐analysis
Authors: Mustafa Hiba J. , Aghajani Faezeh , Patrick Elise , Baerz Maryam M. , Arias‐Sánchez Pedro , Khalil Asma 
Published: February 2024

AbstractIntroductionOur objective was to investigate outcomes in twin‐to‐twin transfusion syndrome (TTTS) treated with fetoscopic laser surgery (FLS) at <18 weeks vs ≥18 weeks, and to conduct subgroup analysis of TTTS with FLS at <16 weeks vs 16–18 weeks.Material and methodsPubMed, Scopus and Web of Science were searched systematically from inception until May 2023. Primary outcome was survival, and secondary outcomes included preterm premature rupture of membranes (PPROM), preterm birth and gestational age (GA) at delivery.ResultsNine studies encompassing 1691 TTTS pregnancies were included. TTTS stage III was significantly more common in TTTS pregnancies treated with FLS at <18 weeks (odds ratio [OR] 2.84, 95% confidence interval [CI] 1.24–6.54), and procedure duration was shorter at <18 weeks (MD −5.27 minutes, 95% CI −9.19 to −1.34). GA at delivery was significantly earlier in TTTS pregnancies treated with FLS at <18 weeks (MD −3.12 weeks, 95% CI −6.11 to −0.13). There were no significant differences in outcomes, including PPROM, PPROM at <7 days post‐FLS, preterm birth at <28 and <32 weeks, delivery at <7 days post‐FLS, and survival outcomes, including fetal demise, live birth and neonatal survival. Similarly, TTTS stage III was more common in TTTS with FLS at <16 weeks than at 16–18 weeks (OR 2.95, 95% CI 1.62–5.35), with no significant differences in the aforementioned outcomes.ConclusionsIn early TTTS treated with FLS, outcomes were comparable between those treated at <18 weeks compared with ≥18 weeks except for GA at delivery, which was 3 weeks earlier. In the subset treated at <16 weeks vs 16–18 weeks, the procedure was feasible without an increased risk of very early preterm birth or perinatal mortality.
A higher proportion of children aged 4 years were referred to speech and language therapists after the introduction of a new language screening tool
Authors: Dahlberg Anton , Levin Anna , Fäldt Anna 
Published: February 2024

AbstractAimLanguage difficulties in children can have enduring impacts on their academic and emotional well‐being. Consequently, early identification and intervention are critical. This study aimed to investigate the impact of introducing Språkfyran, a language screening tool, on the identification and referral rates for speech and language assessment compared to the previous method.MethodsAn observational study was conducted in Gotland, Sweden, using the medical records of 3537 children (53% boys) who were 3–4 years of age. The study period lasted between 5 January 2016 and 29 April 2022, encompassing data collection both before and after the introduction of Språkfyran.ResultsFollowing the introduction of Språkfyran, 15% failed the screening, compared to 20% with the previous speech test. However, referrals for assessment increased significantly with Språkfyran, rising to 7% compared to 3% with the speech test.ConclusionThe proportion of children who failed the Språkfyran screening was consistent with findings from previous studies. Children who failed the screening were more likely to be referred for speech and language assessment after the introduction of Språkfyran. This indicates that Språkfyran is a clinically relevant tool that promotes children's language development through increased referral rates.
Impact of institutional volume on short‐ and long‐term outcomes after laparoscopic colectomy
Authors: Takamura Yuma , Tominaga Tetsuro , Nonaka Takashi , Oishi Kaido , Noda Keisuke , Hashimoto Shintaro , Shiraishi Toshio , Ono Rika , Hisanaga Makoto , Takeshita Hiroaki , Ishii Mitsutoshi , Fukuoka Hidetoshi , To Kazuo , Tanaka Kenji , Sawai Terumitsu , Nagayasu Takeshi 
Published: February 2024

AbstractIntroductionThe impact of institutional volume on postoperative outcomes after laparoscopic colectomy is still being debated. This study aimed to investigate whether differences in postoperative outcomes of laparoscopic colon resection exist between high‐ and low‐volume centers.MethodsData were reviewed for 1360 patients who underwent laparoscopic colectomy for colon cancer between 2016 and 2022. Patients were divided according to whether they were treated at a high‐volume center (≥100 colorectal surgeries annually; n = 947) or a low‐volume center (<100 colorectal surgeries annually; n = 413). Propensity score matching was applied to balance covariates and minimize selection biases that could affect outcomes. Finally, 406 patients from each group were matched.ResultsAfter matching, patients from high‐volume centers showed a higher number of retrieved lymph nodes (19 vs. 17, p < .001) and more frequent involvement of expert surgeons (98.3% vs. 88.4%, p < .001). Postoperative complication rates were similar between groups (p = .488). No significant differences between high‐ and low‐volume centers were seen in relapse‐free survival (88.8% each, p = .716) or overall survival (85.7% vs. 82.8%, p = .480).ConclusionThe present study suggests that in appropriately educated organizations, relatively safe procedures and good prognosis may be obtained for laparoscopic colectomy cases, regardless of institutional volume.
Picture book reading improves children's learning understanding
Authors: Wang Zhenlin , Shao Yihan 
Published: February 2024

AbstractMental state reasoning is an integral part of children's teaching and learning understanding. This study investigated whether a picture book reading approach focusing on mental state discourse and contrasting perspectives in a preschool classroom setting would improve children's teaching and learning understanding and school readiness. In total, 104 children from four classrooms aged between 46 and 64 months (53 girls, M = 54.03 months, SD = 3.68) participated in the study. Half of the classrooms were randomly assigned to an experimental group where teachers read picture books rich in mental state discourse and engaged in intensive discussions with children for eight weeks. Children's false belief understanding and teaching and learning understanding were measured before and after the eight‐week period. The result revealed that picture book reading improved children's learning understanding with a medium effect size, controlling for demographic variables, children's verbal ability, inhibition, and initial false belief understanding. The experimental group children further demonstrated more advanced school readiness 18 months after the intervention ended in a follow‐up study using a teacher questionnaire.
Small RNA‐seq and clinical evaluation of tRNA‐derived fragments in multiple myeloma: Loss of mitochondrial i‐tRFHisGTG results in patients' poor treatment outcome
Authors: Soureas Konstantinos , Papadimitriou Maria‐Alexandra , Malandrakis Panagiotis , Papanota Aristea‐Maria , Adamopoulos Panagiotis G. , Ntanasis‐Stathopoulos Ioannis , Liacos Christine‐Ivy , Gavriatopoulou Maria , Sideris Diamantis C. , Kastritis Efstathios , Dimopoulos Meletios‐Athanasios , Scorilas Andreas , Terpos Evangelos , Avgeris Margaritis 
Published: February 2024

SummaryDespite the substantial progress in multiple myeloma (MM) therapy nowadays, treatment resistance and disease relapse remain major clinical hindrances. Herein, we have investigated tRNA‐derived fragment (tRF) profiles in MM and precursor stages (smoldering MM/sMM; monoclonal gammopathy of undetermined significance/MGUS), aiming to unveil potential MM‐related tRFs in ameliorating MM prognosis and risk stratification. Small RNA‐seq was performed to profile tRFs in bone marrow CD138+ plasma cells, revealing the significant deregulation of the mitochondrial internal tRFHisGTG (mt‐i‐tRFHisGTG) in MM versus sMM/MGUS. The screening cohort of the study consisted of 147 MM patients, and mt‐i‐tRFHisGTG levels were quantified by RT‐qPCR. Disease progression was assessed as clinical end‐point for survival analysis, while internal validation was performed by bootstrap and decision curve analyses. Screening cohort analysis highlighted the potent association of reduced mt‐i‐tRFHisGTG levels with patients' bone disease (p = 0.010), osteolysis (p = 0.023) and with significantly higher risk for short‐term disease progression following first‐line chemotherapy, independently of patients' clinical data (HR = 1.954; p = 0.036). Additionally, mt‐i‐tRFHisGTG‐fitted multivariate models led to superior risk stratification of MM patients' treatment outcome and prognosis compared to disease‐established markers. Notably, our study highlighted mt‐i‐tRFHisGTG loss as a powerful independent indicator of post‐treatment progression of MM patients, leading to superior risk stratification of patients' treatment outcome.
Cell cycle heterogeneity and plasticity of colorectal cancer stem cells
Authors: Higa Tsunaki , Nakayama Keiichi I. 
Published: February 2024

AbstractCancer stem cells (CSCs) are a long‐lived and self‐renewing cancer cell population that drives tumor propagation and maintains cancer heterogeneity. They are also implicated in the therapeutic resistance of various types of cancer. Recent studies of CSCs in colorectal cancer (CRC) have uncovered fundamental paradigms that have increased understanding of CSC systems in solid tumors. Colorectal CSCs share multiple biological properties with normal intestinal stem cells (ISCs), including expression of the stem cell marker Lgr5. New evidence suggests that colorectal CSCs manifest substantial heterogeneity, as exemplified by the existence of both actively cycling Lgr5+ CSCs as well as quiescent Lgr5+ CSCs that are resistant to conventional anticancer therapies. The classical view of a rigid cell hierarchy and irreversible cell differentiation trajectory in normal and neoplastic tissues is now challenged by the finding that differentiated cells have the capacity to revert to stem cells through dynamic physiological reprogramming events. Such plasticity of CSC systems likely underlies both carcinogenesis and therapeutic resistance in CRC. Further characterization of the mechanisms underpinning the heterogeneity and plasticity of CSCs should inform future development of eradicative therapeutic strategies for CRC.
CEO personal experiences and innovation conservatism: Evidence from China
Authors: Dong Bin , Wang Dengli , Wang William Senyu , Feng Min 
Published: February 2024

AbstractResearch question/issueThis paper studies the relationship between chief executive officers' (CEOs) personal experiences and corporate innovation in China.Research findings/insightsWe find that CEOs' famine and military experiences adversely impact firm innovation outcomes. In particular, our channel tests show that CEOs with famine experience adversely affect firm innovation by reducing both R&D expenditures and innovation efficiency, whereas CEOs with military experience hinder innovation mainly by reducing research staff.Theoretical/academic implicationsOur results imply that innovation conservatism in some firms may be partly explained by individual CEO's early‐life personal experiences. Our study thus has broader implications for the differences in management style across corporate executives who go through different experiences.Practitioner/policy implicationsOur findings provide important insights for policy makers, suggesting that they should consider CEOs' early‐life exposure to different experiences as important “soft information” when evaluating firms' innovation potential for government subsidies.
Mother of all bonds: Influences on spatial association across the lifespan in capuchins
Authors: Godoy Irene , Korsten Peter , Perry Susan E. 
Published: February 2024

AbstractIn humans, being more socially integrated is associated with better physical and mental health and/or with lower mortality. This link between sociality and health may have ancient roots: sociality also predicts survival or reproduction in other mammals, such as rats, dolphins, and non‐human primates. A key question, therefore, is which factors influence the degree of sociality over the life course. Longitudinal data can provide valuable insight into how environmental variability drives individual differences in sociality and associated outcomes. The first year of life—when long‐lived mammals are the most reliant on others for nourishment and protection—is likely to play an important role in how individuals learn to integrate into groups. Using behavioral, demographic, and pedigree information on 376 wild capuchin monkeys (Cebus imitator) across 20 years, we address how changes in group composition influence spatial association. We further try to determine the extent to which early maternal social environments have downstream effects on sociality across the juvenile and (sub)adult stages. We find a positive effect of early maternal spatial association, where female infants whose mothers spent more time around others also later spent more time around others as juveniles and subadults. Our results also highlight the importance of kin availability and other aspects of group composition (e.g., group size) in dynamically influencing spatial association across developmental stages. We bring attention to the importance of—and difficulty in—determining the social versus genetic influences that parents have on offspring phenotypes.Research Highlights
Having more maternal kin (mother and siblings) is associated with spending more time near others across developmental stages in both male and female capuchins.
Having more offspring as a subadult or adult female is additionally associated with spending more time near others.
A mother's average sociality (time near others) is predictive of how social her daughters (but not sons) become as juveniles and subadults (a between‐mother effect).
Additional variation within sibling sets in this same maternal phenotype is not predictive of how social they become later relative to each other (no within‐mother effect).
When all speak, should we listen? A cross‐country analysis of disagreement in policymaking and its implications
Authors: Banerjee Spandan , Paramanik Rajendra N. , Sil Rounak , Kurup Unninarayanan 
Published: February 2024

AbstractThis study proposes an ‘implicit measure’ of disagreement to investigate presence of any latent discord in the policy briefings of central banks across nations. We analyse Monetary policy statements of the Bank of Japan (Japan), Banco Central do Brasil (Brazil) and Central Bank of the Republic of Turkey (Türkiye) on both specific as well as overall economic outlook by using novel text mining tools. Subsequently, we explore the relationship of the proposed measure of implicit disagreement with the accuracy of growth and inflation forecasts. Our findings confirm that disagreement/discord among policymakers over varied economic aspects provides signals to forecasters and helps in aligning their forecasts better. The results of this study indicate that disagreement too can be considered as a plausible criterion that can explain the forecaster's belief thereby playing a positive role in ‘forecaster learning’.
Art in times of crisis
Authors: David Géraldine , Li Yuexin , Oosterlinck Kim , Renneboog Luc 
Published: February 2024

AbstractWe trace the long‐term performance of the UK art market across a broad set of crises: world wars, economic recessions, financial crises, inflationary periods, and changes in monetary policy. By means of digitalized historical auction archives, we construct art price indices from the early twentieth century onwards and disclose that annual art auction value grew, in real terms, more than seven‐fold over this period. The arithmetic annual real return and risk amount to 3.6 per cent and 20.1 per cent, respectively. Art returns plummeted at the onset of wars, but turned positive in the second half of wars when they outperformed stocks, suggesting that art was seen as a safe haven in times of political turmoil. During wars, smaller – and thus more transportable – paintings obtained higher returns. Art returns are sensitive to economic and financial crises, with the largest slumps occurring during the Great Depression, oil crisis, recessions of the early 1980s and early 1990s, and the Great Recession. We also document changes in art preferences for paintings’ sizes, schools, liquid art, and artists’ nationalities across crises. Art enters a broad optimal asset portfolio both in non‐crisis periods and during war times.
Courts as an arena for socioenvironmental change: Lessons from the Argentine courts
Authors: Khadim Asmaa 
Published: February 2024

AbstractTrends in the Argentine courts indicate a judicial preference towards flexibility in light of possibly serious environmental consequences, particularly in relation to mining. Through a liberal interpretation of constitutional provisions where collective environmental rights are threatened, the courts have expanded access to justice, leading some to view the Argentine judiciary as “interventionist” or “political”. However, judicial decisions emphasise compliance with constitutional mandates without necessarily encroaching on policy‐making realms. The constitutionalisation of environmental rights has had a strong influence on the judiciary's approach, but in combination with other factors, particularly civic mobilisation, institutional changes and an evolving public ethos on environmental protection. Proactive judicial engagement with the full extent of its powers to ensure that policy‐makers meet their constitutionally mandated obligations can compel policy‐makers to address sustainability issues and rethink strategies. This positioning of the judiciary as a catalyst for more effective environmental governance offers useful insights for European courts.