bluuebunny/crossref_metadata_2025_split huggingface dataset:
Uterine rupture at scar of prior laparoscopic cornuostomy after vaginal delivery of a full‐term healthy infant
Authors: Su Chi Feng , Tsai Horng Jyh , Chen Gin Den , Shih Yang Tse , Lee Maw Sheng 
Published: September 2008

AbstractA 30‐year‐old, gravida 2, para 0 woman who had a history of a laparoscopic cornuostomy for a left interstitial pregnancy was admitted for a vaginal delivery due to labor pains at 40 weeks gestation. A prolonged placental delivery, persistent abdominal pain, and hemorrhagic shock were noted after the delivery of the infant. An emergency laparotomy was carried out, and the diagnosis of a uterine rupture at the scar of a prior cornuostomy was confirmed. The entire placenta extruded through the rupture wound into the abdominal cavity. A Medline computer search revealed that a similar case of a uterine rupture after full‐term vaginal delivery has yet to be reported. In order to prevent a uterine rupture, we suggest that a planned cesarean delivery, before the onset of labor in a subsequent pregnancy, may be safer for a patient with a scarred uterus from a prior cornuostomy for an interstitial pregnancy.
Transitional cell carcinoma of the ovary: Unusual presentation as metastatic cervical lymph node
Authors: Keepanasseril Anish , Suri Vanita , Gupta Nalini , Ghoshal Sushmita 
Published: September 2008

AbstractTransitional cell carcinoma (TCC) of the ovary is a rare and recently recognized subtype of ovarian surface epithelial cancer. We present a case that presented with metastatic cervical lymph nodes which is an extremely rare presentation of an ovarian carcinoma.
First case of liposarcoma arising from the fallopian tube: Case report and review of the literature
Authors: Oishi Hitomi , Moriyama Shingo , Kotera Kouhei , Miura Kiyonori , Masuzaki Hideaki 
Published: September 2008

AbstractLiposarcoma is the most common soft tissue sarcoma in adults, and it typically occurs in either the retroperitoneum or the extremities. However, this malignant tumor is very rare in the female reproductive system. A 58‐year‐old woman presented with acute abdominal pain, and computed tomography (CT) scan detected multiple masses measuring 4–6 cm in size with a fatty density in her adnexal region. Laparoscopic evaluation revealed tumors of the left fallopian tube with a normal left ovary. Histopathological evaluation of the resected pelvic tumors showed lipocytes and lipoblasts of various sizes, leading to diagnosis of well‐differentiated liposarcoma of the left adnexal region. This is the first known case of a liposarcoma arising from the fallopian tube. When a pelvic mass with fatty density that does not show typical findings of a mature cystic teratoma is detected by either CT or magnetic resonance imaging, the possibility of a liposarcoma should be considered.
Leiomyosarcoma of the uterine cervix in a young woman
Authors: Sahu Latika , Bupathy A. , Badhe Bhavana A. 
Published: September 2008

AbstractPrimary leiomyosarcoma of the uterine cervix is an exceedingly rare tumor. Probably, this is first case to be reported in a young woman. A 25‐year‐old south Indian woman presented with excessive white discharge per vaginum. On examination, a growth in the cervix infiltrating to the anterior vaginal wall was present. Biopsy showed leiomyosarcoma. Two cycles of chemotherapy with cisplatin, doxorubicin and cyclophosphamide were given and then a total hysterectomy with bilateral salpingo‐oophorectomy was carried out, followed by local radiation to the anterior vaginal wall. The patient developed extensive metastasis within 6 months of surgery. Because the number of reported cases is very small, the optimal mode of treatment is yet to be established. Additional cases are needed to establish the optimal mode of management and to predict the prognosis.
Pelvic inflammatory disease with Tc‐99m Ciprofloxacin imaging
Authors: Im Moon Whan , Choe Wonsick , Hwang Sung Ook , Song Eun‐Seop , Lee Woo Young 
Published: September 2008

AbstractThe clinical diagnosis of pelvic inflammatory disease (PID) is inexact. There are multiple potential symptoms and signs ascribable to PID as predicted by areas of inflammatory involvement. No symptoms or signs are pathognomonic for PID. The authors describe single photon emission computed tomography (SPECT) images of technetium‐99m (99mTc) ciprofloxacin imaging of patients with PID that showed foci of significantly increased uptake in the regions corresponding to the areas of clinical symptoms. We report two such cases of PID. We undertook physical exams, complete blood count, erythrocyte sedimentation rate, C‐reactive protein, Gram stains, wet smears, cultures, Mycoplasma genetic studies, Chlamydia cultures, and SPECT before treatment. During treatment we took laparoscopies, hysteroscopies, biopsies, and cultures. After the treatment, we repeated the same exams. 99mTc ciprofloxacin imaging is considered valuable in persons with symptoms of PID in whom diagnosis is difficult.
Two cases of epidural anesthesia‐associated postoperative decubitus
Authors: Takahashi Eri , Isonishi Seiji , Suzuki Michiko , Ogura Asako , Kunito Shiro , Hirama Masanori , Shoji Hirokazu , Ochiai Kazuhiko , Tanaka Tadao 
Published: September 2008

AbstractVery few cases of postoperative decubitus have been reported. We report two cases of hip decubitus after myomectomy. Case 1 is a 32‐year‐old Japanese woman who underwent an uncomplicated myomectomy under the combination of general and epidural anesthesia. Twelve hours after surgery, a palpable soft tissue mass developed in the sacral region. On day 3, the soft tissue mass had disappeared and the patient was discharged on day 8. Case 2 is a 33‐year‐old woman. Under a combination of spinal and epidural anesthesia, a myomectomy was carried out. On day 1 after surgery, a hard mass with redness was detected. On day 8, decubitus improved and she was discharged. We evaluated the temporal changes in anesthetic level in four independent cases. Eighteen hours after surgery, the anesthetic effect still continued below the L2 level. We conclude that the extended effect of epidural anesthesia might be one of the mechanisms causing postoperative decubitus.
Joint Generalized Estimating Equations for Multivariate Longitudinal Binary Outcomes with Missing Data: An Application to Acquired Immune Deficiency Syndrome Data
Authors: Lipsitz Stuart R. , Fitzmaurice Garrett M. , Ibrahim Joseph G. , Sinha Debajyoti , Parzen Michael , Lipshultz Steven 
Published: September 2008

SummaryIn a large, prospective longitudinal study designed to monitor cardiac abnormalities in children born to women who are infected with the human immunodeficiency virus, instead of a single outcome variable, there are multiple binary outcomes (e.g. abnormal heart rate, abnormal blood pressure and abnormal heart wall thickness) considered as joint measures of heart function over time. In the presence of missing responses at some time points, longitudinal marginal models for these multiple outcomes can be estimated by using generalized estimating equations (GEEs), and consistent estimates can be obtained under the assumption of a missingness completely at random mechanism. When the missing data mechanism is missingness at random, i.e. the probability of missing a particular outcome at a time point depends on observed values of that outcome and the remaining outcomes at other time points, we propose joint estimation of the marginal models by using a single modified GEE based on an EM-type algorithm. The method proposed is motivated by the longitudinal study of cardiac abnormalities in children who were born to women infected with the human immunodeficiency virus, and analyses of these data are presented to illustrate the application of the method. Further, in an asymptotic study of bias, we show that, under a missingness at random mechanism in which missingness depends on all observed outcome variables, our joint estimation via the modified GEE produces almost unbiased estimates, provided that the correlation model has been correctly specified, whereas estimates from standard GEEs can lead to substantial bias.
Sir Godfrey Thomson: A Statistical Pioneer
Authors: Bartholomew David J. , Deary Ian J. , Lawn Martin 
Published: September 2008

SummaryGodfrey Thomson (1881–1955) was a leading figure in intelligence testing who made his name in that field first at Armstrong College, Newcastle, and then at the University of Edinburgh. In the course of his practical work he identified many theoretical problems which were essentially statistical in character. In particular, he used maximum likelihood estimation as early as 1919 and his statistical work largely set the course of modern factor analysis and related techniques. His statistical abilities were recognized, at different stages of his career, by both Karl Pearson and Sir Ronald Fisher. His key insight was to recognize the importance of Fisherian inference for the future of that subject.
Another Look into the Effect of Premarital Cohabitation on Duration of Marriage: An Approach Based on Matching
Authors: Mazzuco Stefano 
Published: September 2008

SummaryThe paper proposes an alternative approach to studying the effect of premarital cohabitation on subsequent duration of marriage on the basis of a strong ignorability assumption. The approach is called propensity score matching and consists of computing survival functions conditional on a function of observed variables (the propensity score), thus eliminating any selection that is derived from these variables. In this way, it is possible to identify a time varying effect of cohabitation without making any assumption either regarding its shape or the functional form of covariate effects. The output of the matching method is the difference between the survival functions of treated and untreated individuals at each time point. Results show that the cohabitation effect on duration of marriage is indeed time varying, being close to zero for the first 2–3 years and rising considerably in the following years.
Optical coherence tomography imaging of bullous diseases
Authors: Mogensen M , Morsy HA , Nurnberg BM , Jemec GBE 
Published: September 2008

AbstractBackground  Optical coherence tomography (OCT) is a non‐invasive optical imaging technique with a micrometer resolution that may potentially offer real‐time bedside imaging of sufficient detail to allow for morphological discrimination between different types of bullae.Objective  To explore the potential of OCT in bullous skin disorders by looking at a set of patients with skin blisters of known origin and study the OCT images for possible hallmarks of the blistering level.Materials and methods  OCT provides cross‐sectional, tomographic images of the skin. A consecutive series of patients were recruited and their lesions imaged by OCT: 3 patients with bullous pemphigoid (BP), 1 patient with extensive bullae following burns, 1 patient with pemphigus, 1 patient with subcorneal pustular dermatosis, and a patient with Dariers disease. The latter two were included due to similarity to pemphigus with respect to the level of defect cell adhesion.Results  In OCT images, BP bullae are easily depicted as dark, ovoid to round well‐demarquated areas, and BP bulla morphology is clearly different from the burn blisters and the pemphigus‐like disease with respect to the blistering level.Discussion  Differentiation of epidermal and subepidermal blisters is demonstrated using OCT. The variation within pemphigoid lesions and pemphigus‐like diseases is however too subtle to allow for differential diagnosis; this may be ascribed to limited resolution. Enhanced resolution of OCT may overcome this obstacle.
Expression of mutant SOD1G93A in astrocytes induces functional deficits in motoneuron mitochondria
Authors: Bilsland Lynsey G. , Nirmalananthan Niranjanan , Yip Jing , Greensmith Linda , Duchen Michael R. 
Published: September 2008

AbstractAmyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disorder characterized by motoneuron degeneration resulting in paralysis and eventual death. ALS is regarded as a motoneuron‐specific disorder but increasing evidence indicates non‐neuronal cells play a significant role in disease pathogenesis. Although the precise aetiology of ALS remains unclear, mutations in the superoxide dismutase (SOD1) gene are known to account for approximately 20% of familial ALS. We examined the influence of SOD1G93A expression in astrocytes on mitochondrial homeostasis in motoneurons in a primary astrocyte : motoneuron co‐culture model. SOD1G93A expression in astrocytes induced changes in mitochondrial function of both SOD1G93A and wild‐type motoneurons. In the presence of SOD1G93A astrocytes, mitochondrial redox state of both wild‐type and SOD1G93A motoneurons was more reduced and mitochondrial membrane potential decreased. While intra‐mitochondrial calcium levels [Ca2+]m were elevated in SOD1G93A motoneurons, changes in mitochondrial function did not correlate with [Ca2+]m. Thus, expression of SOD1G93A in astrocytes directly alters mitochondrial function even in embryonic motoneurons, irrespective of genotype. These early deficits in mitochondrial function induced by surrounding astrocytes may increase the vulnerability of motoneurons to other neurotoxic mechanisms involved in ALS pathogenesis.
Dose–response effect of ferulic acid against nicotine‐induced tissue damage and altered lipid levels in experimental rats: a pathohistological evaluation
Authors: Adluri Ram Sudheer , Nagarajan Devipriya , Periyaswamy Vishwanathan , Venugopal Padmanabhan Menon 
Published: September 2008

AbstractIn the present study, ferulic acid (FA), a naturally occurring nutritional compound, was investigated for its protective effect against nicotine‐induced toxicity in a dose dependent manner. The toxicity was induced by subcutaneous injection of nicotine at a dose of 2.5 mg/kg body weight (b.w.) for 22 weeks in female albino Wister rats. Simultaneously, rats were treated with FA at three different doses (10, 20 and 40 mg/kg b.w.) via intragastric intubations for 22 weeks. At the end of the experiment, circulatory marker enzymes (i.e. lactate dehydrogenase and alkaline phosphatase) and tissue (lung, liver and kidney) lipid levels (i.e. cholesterol, free fatty acids, triglycerides and phospholipids) were analysed, which were significantly increased in the nicotine‐treated group, whereas FA treatment positively modulated these levels. FA at a dose of 20 mg/kg b.w. was found to be more effective when compared with the other two doses. The lung, liver and kidney excised from the different groups were fixed and stained to perform histological assessments. The protective effect of FA on histological observations confirms that 20 mg/kg b.w. of FA modulates the deleterious effects of nicotine. The results suggest that FA exerts its inhibitory action against nicotine‐induced tissue damage through its antioxidant and antihyperlipidemic properties.
Dental anxiety and quality of life: the effect of dental treatment
Authors: Vermaire J. H. , De Jongh Ad , Aartman Irene H. A. 
Published: September 2008

Abstract –  Objective:  The aim of the present study was to determine the association between dental anxiety and quality of life (QoL) and to test the hypothesis that treatment of highly anxious patients would significantly enhance QoL.Material and methods:  Subjects were 35 highly anxious dental patients of a Dutch dental fear clinic who were assessed on dental trait anxiety (DAS and S‐DAI) and QoL (oral health‐related QoL with the use of OHIP‐14, dental anxiety‐related QoL with the SADAS, and general aspects of QoL using Global Assessment of Functioning, while five different aspects of life satisfaction were quantified on a VAS‐scale) both prior to and after treatment (an average of six sessions of 45–60 minutes each). Also, both objective (DMFT and dentists’ judgement) and subjective (patients’ judgement) indices of oral health status were recorded.Results:  Higher dental anxiety was significantly associated with lower OH‐QoL as indexed by the OHIP‐14 (r = 0.51–0.56, P < 0.01). Treatment was associated with marked improvement on oral health status, reduction of dental anxiety, and improvements regarding a variety of aspects of QoL (all Ps < 0.001). Reduction of dental anxiety, rather than improved oral health, was found to predict enhanced OH‐QoL.Conclusion:  The results underline the importance of applying effective treatment methods for dentally anxious patients, not only with the purpose to alleviate their dental anxiety and to improve their oral health, but also because it contributes to an enhancement of their QoL.
Parsimonious prediction model for the prevalence of dental visits
Authors: Seirawan Hazem 
Published: September 2008

Abstract –  Objectives:  To analyze the prevalence of dental visits within the last year in the Behavioral Risk Factor Surveillance System or BRFSS (2003) national database by simple sociodemographic factors, and to predict prevalence in States that have not participated in BRFSS 2003.Methods:  Behavioral Risk Factor Surveillance System is a cross‐sectional telephone survey conducted by the state‐level authorities in the United States and based on a standardized questionnaire to determine the distribution of risk behaviors and health practices among noninstitutionalized adults. A multivariable logistic regression model considers the complex sample design of the BRFSS was used to predict the prevalence of dental visits based on four nonclinic parsimonious variables.Results:  White race, high income (≥$35 000), education above high school, and marital status were associated with an annual dental visit with odds ratios of 1.38, 2.09, 1.61, and 1.18, respectively. Utah had the highest percentage (78%) of estimated annual users, while ‘Virgin Islands’ had the lowest percentage (59%). The model’s correct classification rate was 61.5%.Conclusions:  State and local governments, health promotion organizations, insurance companies, and organizations that administer public health programs (such as Medicare and Medicaid in the U.S.) will benefit by applying this model to the available nonclinical databases, and will be able to improve planning of dental health services and required dental workforce.
Palestinian experience with sewage sludge utilizing reed beds
Authors: Nassar Abdel Majid , Smith Mike , Afifi Samir 
Published: September 2008

AbstractManagement of sewage sludge is one of the main environmental problems in Palestine. More than 400 m3/day of aerobic sludge and 5000 m3/year of anaerobic sludge are disposed of randomly in the Gaza Strip, creating several environmental and health problems. Because of the political–economic situation, a low cost system for sludge treatment has to be adopted. The results of a pilot project using a reed bed system in the Gaza Strip are promising. Sludge that accumulated in a reed bed system over a 3‐year period was found to be well mineralized and composted, and suitable for land application. The water that drained from the reed bed was found to contain very low concentrations of suspended solids (SS) and chemical oxygen demand (COD). This paper presents the results of a 3‐year project using a reed bed for sewage sludge treatment in Gaza – Palestine. The quality of drained water and the quality and quantity of accumulated sludge were monitored in two drying beds, one planted with reeds and the other left as a conventional drying bed.
How will a room service delivery system affect dietary intake, food costs, food waste and patient satisfaction in a paediatric hospital? A pilot study
Authors: Kuperberg Karen , Caruso Angelina , Dello Susan , Mager Diana 
Published: September 2008

AbstractThe current meal delivery system at The Hospital for Sick Children is a cold‐plating tray delivery system. Our goal was to determine the effect of a room service model on satisfaction, food costs/waste and macronutrient intake in an inpatient paediatric setting. A prospective cross‐sectional study of inpatients (n = 54) was studied over 6 days, 3 days under the current system and 3 days under the pilot model. A satisfaction questionnaire was used to assess satisfaction, and tray tickets were used to assess food costs/waste and dietary intake. With room service, satisfaction increased (P < 0.05), food costs decreased at breakfast and lunch (P < 0.05), and reductions in waste occurred at all meals (P < 0.05). There was an increase in energy, protein, carbohydrate and fat intake (P < 0.05) during lunch. Piloting a room service model in an acute‐care paediatric centre resulted in increased satisfaction, improved dietary intake and reduced food costs and waste, resulting in hospital‐wide implementation.
Thermal death time of Salmonella Typhimurium in oyster meat: establishment and application in a heat‐treated ceviche recipe
Authors: Plaza Ina Isabel B. , Gabriel Alonzo A. 
Published: September 2008

AbstractThe absence of heating processes in the preparation of oyster ceviche makes the dish a potential cause of foodborne illnesses. Hence, this study was conducted to establish the thermal death time at 60°C (D60°C) of the pathogen Salmonella Typhimurium in oyster meat so that it may be applied in the preparation of a heat‐treated oyster ceviche recipe. The established D60°C was used to calculate a heating protocol capable of deactivating 99.999% of the pathogen. Results showed that the heat treatment significantly (P ≤ 0.05) reduced the microbial populations in the oyster meats. Penetrometer and colorimeter measurements of the softness and color characteristics revealed that the heating process significantly influenced these characteristics. However, sensory analyses showed that test panelists did not detect significant differences between the color and texture of control and treatment oyster meats. Only some specific descriptors related to oyster appearance and aroma were given significantly different sensory evaluation scores.
Effective nutrition labeling of restaurant menu and pricing of healthy menu
Authors: Hwang Johye , Lorenzen Carol L. 
Published: September 2008

AbstractProviding nutritional information on restaurant menus may help customers make healthier eating choices. This paper presents the results of a two‐phase study designed to identify (i) the most preferred amount of nutritional information for a menu, (ii) whether presentation of nutritional information influenced healthier choices, and (iii) whether people are willing to pay more for food choices they perceive to be healthier. We found that participants’ attitudes toward the amount of nutritional information and toward the credibility of its source correlated directly to the amount of nutritional information presented; the more nutritional information presented, the more helpful the information and the more credible the source. Additionally, the participants’ nutrition‐related and overall attitudes toward a menu item were influenced by the provision of nutritional information. The participants showed the most positive attitudes toward a low‐fat item and were willing to pay more for that item when nutrition information was provided.