bluuebunny/crossref_metadata_2025_split huggingface dataset:
Upaya Pencegahan Obesitas Remaja Melalui Pendampingan dan Edukasi Label Gizi Serta Penerapan Kunci Jajan Sehat Bergizi
Authors: Lestari Widya Asih , Iswahyudi Iswahyudi 
Published: April 2024

Remaja meruapakan usia yang rentan terhadap masalah gizi. Permasalahan gizi pada remaja saat ini masuk kedalam kategori Triple Burden Malnutrisi yaitu kekurangan gizi, kelebihan berat badan, dan juga defisiensi mikronutrien. Penyebab masalah gizi pada remaja saat ini salah satunya diakibatkan karena pola asupan makan yang tidak sehat. Pola makan remaja saat ini cenderung tinggi energi, tinggi lemak, tinggi natrium, tinggi gula, dan rendah serat. Hal ini didukung juga dengan banyaknya jajanan kekinian yang rendah zat gizi beredar di kalangan remaja. Pola makan yang tidak sehat berdampak pada pertumbuhan dan perkembangan yang tidak optimal serta lebih rentan terhadap penyakit kronis, seperti penyakit degeneratif. Kurangnya perhatian dalam membaca label informasi gizi secara tidak langsung akan berpengaruh terhadap pemilihan makanan dan pola asupan yang tidak sesuai. Hal ini dikarenakan masih rendahnya kesadaran, pengetahuan dalam penggunaan label makanan, serta kemampuan dalam mengartikan informasi zat gizi untuk menentukan pilihan makanan yang sehat. Tujuan: melakukan pendapingan agar para remaja mengetahui dan mengimplementasikan membaca informasi gizi dan pola makan sehat bergizi. Metode yang digunakan adalah pendampingan berupa edukasi yang dilakukan secara periodik dan praktik membaca label informasi gizi. Mitra Berdasarkan nilai pre-post tes terdapat peningkatan pengetahuan remaja sebesar 76% dalam memahami label informasi gizi dan jajan sehat bergizi. Hasil kegiatan menggambarkan pemahaman remaja dalam membaca label informasi gizi dan penerapan pola makan jajan sehat bergizi.
Pembuatan Mesin Pencacah Biji Jagung dengan Motor Listrik sebagai Penggerak
Authors: Nofriadi Nofriadi , Widodo Tri Wahyu , Fadhlulrahman Zaki , Rosa Yazmendra , Yetri Yuli 
Published: April 2024

Pengolahan biji jagung menjadi jagung halus atau tepung jagung telah banyak dilakukan dengan menggunakan berbagai metode untuk memperoleh hasil yang baik dan maksimal. Namun sampai sekarang masih terus dilakukan penyempurnaan untuk mendapatkan hasil yang optimal. Karena tingginya kebutuhan akan alat pencacah biji jagung, maka dibuatlah mesin pencacah biji jagung dengan motor listrik agar dapat digunakan oleh petani skala kecil atau UMKM. Tujuan dari pembuatan alat ini adalah untuk menghasilkan alat pencacah biji jagung yang komponennya terdiri dari mata pisau, rumah pencacah, hooper, dan saringan. Pembuatan mesin ini untuk membantu petani jagung agar dapat mengolah sendiri hasil panen tanpa harus dijual ke pengepul. Tahapan pembuatan mesin ini adalah: pembuatan komponen, assembly komponen dan pengujian alat. Spesifikasi mesin pencacah biji jagung yang dihasilkan yaitu panjang 890 mm, lebar 420 mm, tinggi 1090 mm, sumber penggerak mesin motor listrik ¼ HP dengan putaran 1400 rpm, poros baja ST 37, bearing berukuran 1 inchi. Sistem transmisi menggunakan poros yang terhubung dengan motor listrik dan dihubungkan dengan langsung dengan mata pisau. Konstruksi rangka menggunakan profil L dengan ukuran 40x40x3 mm dari bahan ST 37, dan kapasitas mesin yaitu 40 kg/jam. Setelah 3 kali pengujian, hasil tidak berbeda jauh dari tingkat kehalusan untuk setiap pengujian. Mesin ini cocok digunakan untuk pemilik lahan peternakan yang luas, karena mudah dibawa-bawa.
Model Pembelajaran Realistic Mathematic Education (RME) terhadap Peningkatan Hasil Belajar Matematika Siswa Sekolah Dasar
Authors: Usklaf Muhammad , Agus Imaludin , Sangila Muhammad Syarwa 
Published: April 2024

This research aims to describe the implementation of the Realistic Mathematics Education (RME) learning model in a fifth-grade classroom at one of the elementary schools in the Bonegunu district and to improve students' mathematics learning outcomes on the subject of spatial structures. The subjects of this classroom action research are 26 fifth-grade students in the school. The research design adopts the Kemmis and Taggart model, which includes planning, action, observation, and reflection. Data collection techniques include observation, interviews, tests, and documentation. Data were analyzed descriptively qualitatively. The results show that the implementation of mathematics learning using the Realistic Mathematics Education (RME) learning model proceeded well according to the prepared plan. Students' learning outcomes in Cycle I were in the good category with a learning completeness percentage of 57.69% and an average of 66.35. It then increased to the very good category with a completeness percentage of 92.31% and an average of 87.50 in Cycle II. These findings indicate that the implementation of the Realistic Mathematics Education learning model in the classroom has a positive impact on improving students' mathematics learning outcomes in elementary school.Keywords: Realistic mathematic education (RME), student’s activity, matehematics learning outcomes.
What Is Early Modern Dramatic Collaboration?
Authors: Maguire Laurie , Smith Emma 
Published: April 2024

Abstract
In this article we scrutinise the anti-theatrical bias implicit in attempts to distinguish between Shakespeare and his collaborators; we attempt a taxonomy of the many different forms that collaborative practice took in the early modern theatre; and we examine the extent to which scholarly attitudes to early modern dramatic collaboration, particularly the tendency to see it as a vertical hierarchy rather than horizontal partnership, are shaped by modern ambivalence to academic collaboration in the humanities.
‘Changed to another form’
Authors: Edelstein Gabriella 
Published: April 2024

Abstract
This article demonstrates how dramatic censorship in London's public theatres necessitated a kind of collaborative playwriting with extra-authorial labourers. In the playbook manuscript of Sir John van Olden Barnauelt, the Master of the Revels, Sir George Buc, and the playhouse scribe, Ralph Crane, engaged in a collaborative process that resulted in the most censored extant dramatic document of the early modern English theatres. The censorship is revealing of how political drama was interpreted by its first readers – it was Buc's exegetical interpretation of Barnauelt as anti-monarchical that led to his collaborative revisions and the play's restructuring. This style of censorship also has wider implications. If almost every play was read and revised by the Master of the Revels and perhaps edited by a scribe, then most early modern drama was collaboratively written.
ДОСЛІДЖЕННЯ ЙМОВІРНІСНОГО ПОКАЗНИКА ФУНКЦІОНАЛЬНОЇ СТІЙКОСТІ РОЗПОДІЛЕНИХ ІНФОРМАЦІЙНИХ СИСТЕМ
Authors: БАРАБАШ Олег , МАКАРЧУК Андрій , САЛАНДА Іванна 
Published: April 2024

На даний час спостерігається активна інформатизація самих різних сфер суспільства. Це є основним фактором того, що все більш активно починають використовувати розподілені інформаційні системи. Оскільки ці інформаційні системи часто є немалими, очікуваними є необхідність в розробці та модифікації методів оцінювання їх функціональної стійкості.
Протягом останніх десятиліть було описано чимало показників функціональної стійкості розподілених інформаційних систем та способів їх обчислення. До них можна віднести такі як реберна та вершинна зв’язність, ймовірність та матриця зв’язності, тощо. Однак, обчислення деяких з них передбачають дуже велику кількість обчислень та, іноді, й інших не менш складних супровідних процесів. Тому виникає необхідність в модифікації цих показників функціональної стійкості з ціллю оптимізації їх обчислення.
В даній роботі досліджується модифікація такого показника функціональної стійкості як згортка матриці зв’язності. На відміну від інших робіт, пропонується використовувати наперед задане ядро замість такого, що залежить від певних параметрів. За рахунок цього досягається спрощення використання даного ймовірнісного показника завдяки відсутності необхідності періодичного перерахунку ядра у випадку змін параметрів системи. Також демонструються особливості поведінки описаної згортки у випадку залежності матриці зв’язності від ймовірності справності ліній зв’язку. В результаті цього показано, що при достатньо великих значеннях цього параметра його невеликі коливання на функціональну стійкість розподіленої інформаційної системи майже не впливають, тобто вона все рівно буде близька до максимально можливої.
Отримані в роботі результати можуть бути використані для більш оптимального оцінювання функціональної стійкості розподілених інформаційних систем та дослідження впливу різних параметрів на неї.
PERILAKU SEKRETARIS BERKORESPONDENSI DIGITAL PADA PT ANGKASA PURA I BALI PERSPEKTIF TAKSONOMI BLOOM
Authors: Suta I Gusti Lanang , Sari Anjli Purnama , Utami Made Ayu Jayanti Prita , Widhari Cokorda Istri Sri 
Published: April 2024

Korespondensi digital merupakan kegiatan dari membuat, mengirim, menerima dan membalas surat dengan memanfaatkan teknologi komunikasi digital. Terdapat 41 responden yang mengisi kuisioner dengan lengkap. 41 responden berprofesi sebagai seketaris atau mengerjakan tugas-tugas sekretaris. Domain perilaku yang diamati dari penelitian berdasarkan klasifikasi yang di kembangkan Bloom yaitu, pengetahuan, sikap dan paktik.Teknik analisa yang digunakan dalam penelitian ini adalah regresi linier berganda yang bertujuan memperoleh gambaran secara menyeluruh mengenai hubungan antar variabel. Selanjutnya menggunakan analisis lain untuk mengintrepertasikan data analisis deskriptif, uji asumsi klasik, serta uji hipotesis secara parsial dan simultan. Hasil penelitian menunjukkan bahwa pengetahuan,sikap dan praktik berpengaruh positif dan signifikan terhadap perilaku sekretaris dalam berkorespondensi digital.
Pengetahuan berpengaruh secara parsial terhadap Perilaku Sekretaris dalam Berkorespondensi digital dengan nilai sebesar 9,204 > 1.683
Sikap berpengaruh secara parsial terhadap Perilaku Sekretaris dalam Berkorespondensi digital dengan nilai sebesar 28,637 > 1.683
Praktik berpengaruh secara parsial terhadap Perilaku Sekretaris dalam Berkorespondensi digital dengan nilai sebesar 10,569 > 1.683
Pengetahuan, Sikap, Praktik berpengaruh secara simultan terhadap Perilaku Sekretaris dalam Berkorespondensi digital dengan nilai sebesar 505,627 > 2.859
Kemampuan prediksi dari ketiga variabel tersebut terhadap perilaku sekretaris dalam berkorespondensi digital sebesar 97.6 % sedangkan sisanya dipengaruhi oleh faktor lain diluar model penelitian.
PENGARUH TANGIBLE, EMPHATY, RELIABILITY, RESPONSIVENESS DAN ASSURANCE TERHADAP KEPUASAN KONSUMEN DI SWALAYAN LUWES PATI
Authors: Wuryano Galih , Ruspitasari Widi , Handoko Yunus 
Published: April 2024

Tujuan penelitian ini adalah untuk mengetahui dan menganalisis: 1) pengaruh tangible terhadap kepuasan konsumen di Swalayan Luwes Pati, 2) pengaruh emphaty terhadap kepuasan konsumen di Swalayan Luwes Pati, 3) pengaruh reliability terhadap kepuasan konsumen di Swalayan Luwes Pati, 4) ntuk pengaruh responsiveness terhadap kepuasan konsumen di Swalayan Luwes Pati, 5) pengaruh assurance terhadap kepuasan konsumen di Swalayan Luwes Pati. Jenis penelitian ini adalah kuantitatif dengan pendekatan survei. Penelitian ini dilakukan pada konsumen yang berbelanja di Swalayan Luwes Pati. Populasi dalam penelitian ini adalah semua konsumen yang berbelanja di Swalayan Luwes Pati, sampel dalam penelitian ini sebanyak 100 responden dengan teknik sampling Accidental Sampling selama 1 bulan. Hasil penelitian menunjukkan 1) tangible berpengaruh secara signifikan terhadap kepuasan konsumen, 2) emphaty berpengaruh secara signifikan terhadap kepuasan konsumen, 3) reliability berpengaruh secara signifikan terhadap kepuasan konsumen, 4) responsiveness berpengaruh secara signifikan terhadap kepuasan konsumen dan 5) assurance tidak berpengaruh secara signifikan terhadap kepuasan konsumen
Transtibial amputelerde pozisyon hissi ile yürüyüş ve denge arasındaki ilişki
Authors: Baş Sevilay Seda , Anafaroğlu Külünkoğlu Bahar , Çerezci Duygu Senay 
Published: April 2024

Amaç: Bu çalışmanın amacı, tek taraflı transtibial amputelerde gövde ve diz pozisyon hislerinin, yürüyüş parametreleri ve denge ile olan ilişkisinin incelenmesidir. Yöntem: Bu kesitsel çalışmaya, tek taraflı transtibial amputasyon geçirmiş ve bağımsız yürüyebilen 18-65 yaş arası bireyler dahil edildi. Katılımcıların gövde ve diz pozisyon hisleri digital bir inklinometre ile, yürüyüşlerine ait zaman-mesafe parametreleri ve pelvik hareketlerine ait değişkenler yürüyüş sensörü ile, dinamik dengeleri ise 4 kare adım testi ile değerlendirildi. Bulgular: Çalışmaya katılan bireylerin (22 E, 3 K) ortalama yaşları 43.32±13.75 yıl olarak kaydedildi. Katılımcıların ampute ve ampute olmayan diz pozisyon hislerinin arasında istatistiksel açıdan anlamlı fark bulundu. Ampute taraf diz eklem pozisyon hissi mutlak hatası ile ampute taraf pelvik internal/eksternal rotasyonu ve ampute olmayan taraf pelvik internal/eksternal rotasyonu arasında negatif yönde orta dereceli korelasyon; ve gövde pozisyon hissi ile ampute taraf posterior pelvik tilt ve kadans arasında pozitif yönde orta derecede korelasyon, gövde pozisyon hissi ile ampute taraf pelvik eksternal rotasyon ve ampute olmayan taraf pelvik internal rotasyon arasında negatif yönde orta derecede korelasyon bulundu. Sonuç: Ampute diz ve gövde pozisyon hissi ile yürüyüş parametreleri arasında ilişki tespit edildi. Bu ilişki yürüyüş deviasyonlarına, alt ekstremite ve gövdeye ait yapıların zorlanmasına ve bu yapılarda yaralanma riskinin ortaya çıkmasına neden olabilir. Ampute rehabilitasyon programlarına gövde ve diz eklem pozisyon hislerinin geliştirilmesine yönelik egzersizlerin eklenmesi bu riskleri azaltabilir.
Application of machine learning to predict unbound drug bioavailability in the brain
Authors: Morales J. Francisco , Ruiz M. Esperanza , Stratford Robert E. , Talevi Alan 
Published: April 2024

Purpose: Optimizing brain bioavailability is highly relevant for the development of drugs targeting the central nervous system. Several pharmacokinetic parameters have been used for measuring drug bioavailability in the brain. The most biorelevant among them is possibly the unbound brain-to-plasma partition coefficient, Kpuu,brain,ss, which relates unbound brain and plasma drug concentrations under steady-state conditions. In this study, we developed new in silico models to predict Kpuu,brain,ss.Methods: A manually curated 157-compound dataset was compiled from literature and split into training and test sets using a clustering approach. Additional models were trained with a refined dataset generated by removing known P-gp and/or Breast Cancer Resistance Protein substrates from the original dataset. Different supervised machine learning algorithms have been tested, including Support Vector Machine, Gradient Boosting Machine, k-nearest neighbors, classificatory Partial Least Squares, Random Forest, Extreme Gradient Boosting, Deep Learning and Linear Discriminant Analysis. Good practices of predictive Quantitative Structure-Activity Relationships modeling were followed for the development of the models.Results: The best performance in the complete dataset was achieved by extreme gradient boosting, with an accuracy in the test set of 85.1%. A similar estimation of accuracy was observed in a prospective validation experiment, using a small sample of compounds and comparing predicted unbound brain bioavailability with observed experimental data.Conclusion: New in silico models were developed to predict the Kpuu,brain,ss of drug candidates. The dataset used in this study is publicly disclosed, so that the models may be reproduced, refined, or expanded, as a useful tool to assist drug discovery processes.
Association between nomophobia and learning performance among undergraduate students: the mediating role of depression and anxiety
Authors: Abukhanova Azhar , Almukhambetova Bibigul , Mamekova Assem , Spatay Aygul , Danikeyeva Aigul 
Published: April 2024

BackgroundThere is a gap in the existing literature concerning the connection between nomophobia and diminished academic performance, potentially influenced by anxiety and depression. The present study aimed to examine the relationship between undergraduate students’ nomophobia and learning outcomes, and whether depression and/or anxiety mediate this potential link.MethodsA quantitative cross-sectional survey design was employed. Nomophobia, anxiety, and depression were measured in 307 undergraduate students using validated self-report questionnaires. Learning performance was assessed based on participants’ grade point averages. Correlation analysis and mediation analysis were conducted to test the hypotheses.ResultsThe Pearson correlation analysis and multiple parallel mediation modeling suggest that anxiety plays a significant role as a causal pathway through which nomophobic behavior leads to lower grades among university students compared to their less anxious peers. Depression had no significant mediation effect.ConclusionThe findings support the notion that nomophobia is linked to poor academic achievement. The detrimental impact of nomophobia on learning performance appears to be more closely tied to anxiety rather than depression. This research contributes to the understanding of the complex interplay between technology use, psychological well-being, and educational outcomes in the higher education context. The study’s implications include the validation of the measurement scales in a non-English population and the recognition of the influence of technology on mental health and academic outcomes.
Prediction of glycosylated hemoglobin level in patients with cardiovascular diseases and type 2 diabetes mellitus with respect to anti-diabetic medication
Authors: Ikramov Alisher , Mukhtarova Shakhnoza , Trigulova Raisa , Alimova Dilnoza , Abdullaeva Saodat 
Published: April 2024

Blood glycosylated hemoglobin level can be affected by various factors in patients with type 2 diabetes and cardiovascular diseases. Frequent measurements are expensive, and a suitable estimation method could improve treatment outcomes.Patients and methods93 patients were recruited in this research. We analyzed a number of parameters such as age, glucose level, blood pressure, Body Mass Index, cholesterol level, echocardiography et al. Patients were prescribed metformin. One group (n=60) additionally was taking sitagliptin. We applied eight machine learning methods (k nearest neighbors, Random Forest, Support Vector Machine, Extra Trees, XGBoost, Linear Regression including Lasso, and ElasticNet) to predict exact values of glycosylated hemoglobin in two years.ResultsWe applied a feature selection approach using step-by-step removal of them, Linear Regression on remaining features, and Pearson’s correlation coefficient on the validation set. As a result, we got four different subsets for each group. We compared all eight Machine Learning methods using different hyperparameters on validation sets and chose the best models. We tested the best models on the external testing set and got R2 = 0.88, C Index = 0.857, Accuracy = 0.846, and MAE (Mean Absolute Error) = 0.65 for the first group, R2 = 0.86, C Index = 0.80, Accuracy = 0.75, and MAE = 0.41 for the second group.ConclusionThe resulting algorithms could be used to assist clinical decision-making on prescribing anti-diabetic medications in pursuit of achieving glycemic control.
Toward a new personalized psycho-social approach for the support of prostate cancer and their caregivers dyads: a pilot study
Authors: Cincidda Clizia , Pizzoli Silvia Francesca Maria , Oliveri Serena , Guiddi Paolo , Pravettoni Gabriella 
Published: April 2024

IntroductionProstate cancer patients (PCP) often struggle with a significant emotional, physical, and social burden during the care-flow pathway. Noteworthy, PCP should not be considered a standalone patient, but someone who is connected with a relevant social environment and that is usually supported by a beloved one, the caregiver. The involvement of the caregivers through the care pathway might bring significant benefits both on the psychological and the treatment and decision-making side. The present pilot study aimed at preliminarily assessing quantitatively the psychological impact of a prostate cancer diagnosis on the degree of agreement of PCPs and their caregivers on medical decisions, coping resources and psychological distress levels.Methods16 PCP and their caregivers were enrolled in the study and fulfilled a battery of standardized questionnaires.ResultsResults showed low concordance in decision making styles and preferences in patients and their caregivers and that the dyads showed similar depression symptoms levels. Relevant features of the psychological needs of the analyzed dyads, such as need for information and support, also emerged.ConclusionOn the basis of these preliminary results, guidelines for the construction of tailored brief psychological support interventions for PCP dyads are provided.
Total sleep deprivation alters spontaneous brain activity in medical staff during routine clinical work: a resting-state functional MR imaging study
Authors: Peng Cong , Guo Dingbo , Liu Liuheng , Xiao Dongling , Nie Lisha , Liang Huilou , Guo Dajing , Yang Hua 
Published: April 2024

ObjectivesTo assess the effect of total sleep deprivation (TSD) on spontaneous brain activity in medical staff during routine clinical practice.MethodsA total of 36 medical staff members underwent resting-state functional MRI (rs-fMRI) scans and neuropsychological tests twice, corresponding to rested wakefulness (RW) after normal sleep and 24 h of acute TSD. The rs-fMRI features, including the mean fractional amplitude of low-frequency fluctuation (mfALFF), z-score transformed regional homogeneity (zReHo), and functional connectivity (zFC), were compared between RW and TSD. Correlation coefficients between the change in altered rs-fMRI features and the change in altered scores of neuropsychological tests after TSD were calculated. Receiver operating characteristic (ROC) and logistic regression analyses were performed to evaluate the diagnostic efficacy of significantly altered rs-fMRI features in distinguishing between RW and TSD states.ResultsBrain regions, including right superior temporal gyrus, bilateral postcentral gyrus, left medial superior frontal gyrus, left middle temporal gyrus, right precentral gyrus, and left precuneus, showed significantly enhanced rs-fMRI features (mfALFF, zReHo, zFC) after TSD. Moreover, the changes in altered rs-fMRI features of the right superior temporal gyrus, bilateral postcentral gyrus, left middle temporal gyrus, and left precuneus were significantly correlated with the changes in several altered scores of neuropsychological tests. The combination of mfALFF (bilateral postcentral gyrus) and zFC (left medial superior frontal gyrus and left precuneus) showed the highest area under the curve (0.870) in distinguishing RW from TSD.ConclusionSpontaneous brain activity alterations occurred after TSD in routine clinical practice, which might explain the reduced performances of these participants in neurocognitive tests after TSD. These alterations might be potential imaging biomarkers for assessing the impact of TSD and distinguishing between RW and TSD states.