bluuebunny/crossref_metadata_2025_split huggingface dataset:
Polypoidal carcinosarcoma of the oropharynx: a clinicopathological and immunohistochemical study
Authors: Hansen Lars Trier , Kristensenan Søren , Moesner Jørgen 
Published: November 2007

AbstractPolypoidal squamous cell carcinomas, with a sarcomatous stroma, in the upper aerodigestive tract are very rare but well described tumours. They are associated with a multifario?sjiomenclature because of different opinions regarding their histology and histogenesis. The main issue is whether the stroma component is a true sarcoma or a benign reactive lesion.In order to draw the attention of otolaryngologists and pathologists to the characteristic features of this rare tumour, two cases originating from the oropharynx are presented. Both tumours were pedunculated and polypoidal, and their bulk consisted of a bizarre sarcoma-like stroma covered with granulation tissue. In some areas of the surface, however, atypical squamous cell epithelium with foci of invasive carcinoma was found. In the vicinity of the latter both tumours contained areas of adenocarcinoma. After surgical excision followed by radiation therapy, there was no recurrence after two and five years, respectively.The histological and immunohistochemical findings support the assumption that these two tumours are carcinosarcomas. Adenocarcinomatous elements in this type of tumour have to our kowledge been reported only twice previously and have never been observed in the pharynx.
Terminal duct adenocarcinomas of the parotid gland
Authors: Kemp Bonnie L. , Batsakis John G. , El-Naggar Adel K. , Kotliar Sophia N. , Luna Mario A. 
Published: November 2007

AbstractThe major salivary glands are considered to rarely be the sites of primary terminal duct adenocarcinomas, a neoplasm with a considerable predilection for origin from intraoral minor salivary glands. We present a clinicopathological study of 22 terminal duct adenocarcinomas of the parotid gland, the largest single series to date. A comparison between the parotid neoplasms and over 200 minor salivary gland terminal duct adenocarcinomas indicates there is little difference in biological behaviour and confirms the low-grade quality of the carcinomas, regardless of site of origin.
The laryngectomee and swimming
Authors: Thomas M. R. , Natarajan B. , Garth R. J. N. 
Published: November 2007

AbstractFollowing laryngectomy patients are usually advised that swimming is no longer possible. Under supervised conditions and using a swimming aid, such as described, a laryngectomee may return to an activity previously considered unavailable, rehabilitation thus being more complete. However, for a laryngectomee to proceed a safe supervised environment is required, and the path to this goal is often long and arduous, but with persistent dedication the Laryngectomy Swimming Club may become a reality bringing rich reward.
Tympanic membrane atelectasis in childhood otitis media with effusion
Authors: Tay H. L. , Mills R. P. 
Published: November 2007

AbstractA prospective study on the dynamics of tympanic membrane atelectasis during the treatment for glue ear was performed in a sample of 115 ears of 83 children aged between one and 11 years. The progression in the degree of pars tensa atelectasis was analysed in relation to six potentially relevant factors. Multivariate analysis showed that the factor with the most predictive value on the progression of the pars tensa retraction was the grade of atelectasis at initial detection (p<0.0001). The use of grommets did not have any significant influence on the outcome grade of atelectasis. There was an association between previous grommet insertion and localized retractions in the inferior segment of the pars tensa (P<0.0001). However, localized retractions in the postero-superior quadrant were not associated with previous grommet insertion (P<0.02). Although the hearing thresholds of atelectatic ears were significantly worse than normal ears especially at 4 kHz (p<0.006), the difference was less than 5 dB.
Monitoring fluctuations in nasal patency in children: acoustic rhinometryversusrhinonygrometry
Authors: Fisher Edward W. , Palmer Christopher R. , Lund Valerie J. 
Published: November 2007

AbstractSimple rhinohygrometry and passive rhinomanometry studies have suggested that the ‘nasal cycle’ in children is often different in pattern of that of adults and experimental animals. We aimed to establish whether this assertion was correct, using a reliable and sensitive method, acoustic rhinometry (AR), and to compare results with those of simple rhinohygrometry (RH). Healthy children with no evidence of nasal disease were examined (n = 15; age range three to 10 years; mean age six years). Simultaneous recordings using AR and RH were made on each child every 10–15 minutes over two to four hour periods. Six children underwent nine additional AR studies on separate occasions. ‘Classical’ reciprocal alternating patterns were evident in 80 per cent (12/15) AR and 53 per cent (8/15) RH studies, ‘in concert’ patterns in seven per cent (1/15) AR and 20 per cent (3/15) RH studies and ‘irregular’ patterns in 13 per cent (2/15) AR and 27 per cent (4/15) RH studies. The agreement between the two methods was 47 per cent, with a kappa (K) value of −0.17 (poor agreement compared to chance). Agreements between the acoustic rhinometry parameters were ‘fair’ for all data (K = 0.34) and excellent (K = 1.0) if irregular patterns were ignored. Repeated studies showed that the pattern of fluctuation varies within any particular individual. The nasal cycle is similar in pattern in children and adults, and acoustic rhinometry is currently the method of choice to further investigate and clarify this phenomenon.
KTP-532 laser tonsillectomy – a potential day-case procedure?
Authors: Raine N. M. N. , Whittet H. B. , Marks N. J. , Ryan R. M. 
Published: November 2007

AbstractWe report the results of a prospective pilot study of 54 adult patients undergoing tonsillectomy using the KTP-532 laser, designed to assess whether the technique would facilitate day-case adult tonsillectomy. Subjective and objective assessment at six hours post-operatively showed that only 43 per cent could, in our judgement, have been discharged at this interval. Furthermore, the overall complication rate was 31 per cent with a secondary haemorrhage rate of 19 per cent. We conclude that KTP-532 laser tonsillectomy as performed in this pilot study compares unfavourably with dissection tonsillectomy and we discuss possible reasons for this.
A case with symptoms of vestibular neuronitis caused by an intramedullary lesion
Authors: Tsunoda Atsunobu , Komatsuzaki Atsushi , Muraoka Hideki , Gou-Tsu Kazuo 
Published: November 2007

AbstractWe report on a patient with an intramedullary lesion who showed only symptoms of so-called vestibular neuronitis. From the neurological aspects and MRI findings, the lesion was thought to be localized to the vestibular nerve in the pons. Cerebrospinal fluid testing and MRI findings suggested a diagnosis of multiple sclerosis (MS), although the clinical features were not compatible with MS. This case may shed some light on the aetiology of vestibular neuronitis.
Superficial siderosis of the central nervous system: a case with an unruptured intracranial aneurysm
Authors: Lai Ming-Tang , Ohmichi Takuya , Yuen Koji , Egusa Kentaro , Yorizane Satoshi , Masuda Yu 
Published: November 2007

AbstractWe present a case of superficial siderosis (SS) of the central nervous system (CNS) with an unruptured intracranial aneurysm to illustrate that the commonly encountered unexplainable progressive sensorineural hearing loss (SNHL) can be an important sign for the early awareness of this rare disorder. The literature on SS is reviewed and the pathogenesis of SS is discussed.
Hearing loss and motorcyclists
Authors: McCombe Andrew W. , Binnington Jonathan , Davis Adrian , Spencer Helen 
Published: November 2007

AbstractMotorcyclists are known to be exposed to excessive wind noise levels when riding. The potential adverse effects of this exposure on their hearing was investigated. Temporary threshold shift (TTS) was assessed by asking 18 riders to undertake a standard test run of one hour at a steady 80 mph, and performing audiometry before and immediately afterwards. Permanent threshold shift (PTS) was assessed by performing pure-tone audiograms on a highly screened group of 246 motorcyclists and comparing their hearing thresholds with those of an appropriate control group obtained from the MRC National Study of Hearing.Significant TTS was found at 0.25, 0.5,1 and 2 kHz. The greatest TTS occurred at 1 kHz, with a mean hearing loss of 10.3 dB. The hearing thresholds of the motorcyclists were significantly worse than the controls at 0.25, 0.5, 1 and 2 kHz, andwas most marked at 0.5 and 1 kHz where their hearing loss (PTS) was, respectively, 3.7 and 3.6 dB greater than expected.These findings demonstrate evidence of both temporary and permanent hearing loss from motorcycling and present a strong argument for the need for some form of remedial action.
Expression of EGF, EGFR and PCNA in laryngeal lesions
Authors: Wen Q. H. , Nishimura T. , Miwa T. , Nagayama I. , Furukawa M. 
Published: November 2007

AbstractThe expression of EGF/EGFR in 47 laryngeal surgical specimens from 44 patients was examined. PCNA analysis as an index of proliferating cells was also performed in 32 cases of laryngeal cancer, six cases of pre-cancerous lesions and nine cases of normal laryngeal mucosa. EGFR failed to show a significant correlation with tumour behaviour, but EGF expression was statistically significantly higher in malignant (SCC) than in non-malignant tissues (pre-cancerous and normal tissues) (p<0.006), and PCNA also showed a statistically significant difference (p<0.016) between the two. In malignant tissues when EGF/EGFR in ‘double-positive’ and ‘double-negative’ cases was compared, a statistically significant difference in PCNA was found (p<0.029); but this was not seen in non-malignant tissues. Our results support the hypothesis that an autocrine mechanism exists in laryngeal cancer and in this mechanism EGF may play an important role in tumour progression, especially when EGFR is overexpressed.
The importance of thyroid scanning in neck lumps – a case report of ectopic tissue in the right submandibular region
Authors: Morgan N. J. , Emberton P. , Barton R. P. E. 
Published: November 2007

AbstractWe describe the case of a 50-year-old previously well female, who presented with a slowly growing mass in the right submandibular region. Imaging confirmed the absence of a normally placed thyroid and the presence of a lingual thyroid. The submandibular mass was excised and histological examination confirmed ectopic thyroid tissue. The embryological descent of the thyroid and the Sistrunk procedure are discussed as well as the importance of thyroid scanning in neck lumps.
Carcinoma ex-pleomorphic adenoma of the nasal cavity: a report of two cases
Authors: Cho Kyung Ja , El-Naggar Adel K. , Mahanupab Pongsak , Luna Mario A. , Batsakis John G. 
Published: November 2007

AbstractCarcinoma ex-pleomorphic adenoma is exceedingly rare in sites other than the major salivary glands and the oral cavity. We present the first two histopathologically documented examples to occur in the nasal cavity.From the Department of Pathology, University of Texas, M. D. Anderson Cancer Center, Houston, Texas, USA.
Causes of failure of combined approach tympanoplasty in the treatment of acquired cholesteatomas of the middle ear and the mastoid
Authors: Kapur T. R. 
Published: November 2007

AbstractForty cases of failed combined approach tympanoplasty were analysed. The commonest cause of failure was adhesions between the facial ridge and the tympanic membrane, causing segmental attico-mastoid malaeration in 51.3 per cent of cases followed-up continually. Other causes were, large dermoids, incomplete removal of squamous epithelium, and eustachian tube obstruction. Eustachian tube dysfunction did not appear to be a major cause of failure.
Clinical photographs as teaching aids: how reliable are they?
Authors: McCombe Andrew , Williamson Peter , Hawke Michael 
Published: November 2007

AbstractA study to investigate the value and reliability of clinical photographs as teaching aids was undertaken. Twenty colour photographs were taken using the StarMed video-otoscopic system. The pictures, which were a mixture of normal and abnormal ears, were shown to 21 experienced otolaryngologists from the UK and Canada. These clinicians were asked to identify the abnormality if any.The median score for correctly identified pictures was 15 (range 12–18). This score was identical for both the UK and Canadian subgroups. Although the abnormalities were consistently well recognized with an average correct identification rate of 90 per cent (range 67–100 per cent), the ‘normals’ were recognized significantly less well at only 41 per cent (range 5–71 per cent) (chi-squared = 110.6; 1 df; p<0.001).This result is probably due to failure of the camera to capture the huge variation and subtleties in the range of normal, and the clinicians' natural inclination to identify pathology, when in doubt. We would conclude that as long as this failing is recognized, clinical photographs, and specifically those from the video-otoscope, represent a useful and reliable teaching tool.
Management of retraction pockets of the pars tensa in children by excision and ventilation tube insertion
Authors: Walsh R. M. , Pracy J. P. , Harding L. , Bowdler D. A. 
Published: November 2007

AbstractRetraction pockets of the pars tensa in children can result in erosion of the ossicles leading to hearing loss and eventually cholesteatoma formation. Several different types of treatment for the more severe grades of retraction pocket have been described. The aim of this pilot study was to assess the outcome following simple excision and ventiolation tube insertion of grade II, III and IV retraction pockets of the pars tensa. The eardrums were grades according to Sadé's classification (1979).There were seven grade II and four garade III ratractions. Ten eardrums healed completely in a mean time of 3.6 months (mean follow-up 16 months) and there was one residual perforation. Two retractions recurred and both of these were only grade I. Clinically, an improvement in hearing was reported in seven children (eight ears) and the average air conduction threshold gain for these patients was 16 dB. A larger prospective study is currently underway.
Enophthalmos secondary to maxillary sinus disease: single-stage operative management
Authors: Beasley N. J. P. , Jones N. S. , Downes R. N. 
Published: November 2007

AbstractMaxillary sinus disease can lead to dehiscence of the orbital floor. Using endoscopic sinus surgery it is possible to simultaneously reconstruct the orbital floor and to assess and treat underlying sinus disease.
Ameloblastic carcinoma of the maxilla
Authors: Lolachi Christopher M. , Madan Shashi K. , Jacobs John R. 
Published: November 2007

AbstractAmeloblastic carcinoma is an unusual tumour. There have been a total of 34 cases of ameloblastic carcinoma in the English literature to date. Of these only 11 cases have occurred in the maxilla. The authors report the 12th such case. The histological classification for odontogenic carcinoma has been debated for many years and recently revised, thus differentiating between malignant ameloblastoma and ameloblastic carcinoma. The authors review the current literature regarding diagnosis and treatment of this unusual lesion, and support the use of the term malignant ameloblastoma for the tumours that metastasize in spite of their benign histological appearance, whereas, the ameloblastic carcinoma is referred to as the primary tumour with malignant transformation, regardless of its metastatic potential.
Comparison of the repair of permanent tympanic membrane perforations by hydrocolloidal dressing and paper patch
Authors: Spandow Odd , Hellström Sten , Dahiström Michael , Bohlin Lennart 
Published: November 2007

AbstractThirty consecutive patients with permanent perforations of their tympanic membranes (TM) present from 2.5 to 50 years (mean 18.7 years) were admitted to a prospective study using two alternative methods of dressings for closure of the perforations. An adhesive-coated hydrocolloid material was compared with a conventional dressing of vaseline impregnated rice paper patch after de-epithelialization of the perforation border. Nine of the permanent TM perforations (30 per cent), five with the hydrocolloidal dressing and four with the rice paper patch had healed when followed-up after one year. The size of eight of the central perforations that had healed was equal to or less than 25 per cent of the TM. Also one perforation with a size of 65 per cent had healed. Seven perforations were located in the posterior part of the TM:Jour in the posterior-superior quadrant, one in the inferior quadrant, one had engulfed the posterior half of the TM and one included the anterior-inferior quadrant. Only two perforations out of 14, with a size of 25 per cent or less, located in the anterior-inferior quadrant, healed. No significant difference was demonstrated between the two types of dressings. Both groups noted an immediate improvement in hearing of 10.8 and 9.3 dB, respectively, after application of the dressing.The study demonstrates that application of an occlusive dressing or paper patch in 30 per cent of patients can promote the healing of long-standing perforations. The chances for healing are better if the perforation is located in the posterior part of the TM. This simple technique immediately improved hearing and should be tried before a patient is referred for myringoplasty surgery.
Provox™ valve use for post-laryngectomy voice rehabilitation
Authors: Callanan Vincent , Gurr Paul , Baldwin David , White-Thompson Morwenna , Beckinsale Jane , Bennetf Jane 
Published: November 2007

AbstractThe Provox™ voice prosthesis has been used in our department since September 1992 for postlaryngectomy voice rehabilitation. This prosthesis is an indwelling low-resistance tracheoesophageal valve. The cohort consisted of 28 laryngectomees with a mean follow-up time of 352 days. The average valve life before failure was 148 days. Speech intelligibility of 85 per cent was achieved for complete sentences. No major surgical problems were associated with the valve insertion or its use. Replacement of the prosthesis as an outpatient procedure was accomplished without difficulty.
Latex-Induced allergic rhinitis in a laboratory nurse
Authors: Kujala V. , Pirilä T. , Niinimäki A. , Reijula K. 
Published: November 2007

AbstractA case of occupational rhinitis in association with natural rubber latex hypersensitivity is presented. In the nasal provocation test for natural rubber latex glove powder the nurse experienced rhinorrhoea. A significant increase in the amount of nasal secretion and mucosal oedema could be detected. The patient also showed a positive skin prick test to natural rubber latex allergens, and an elevated natural rubber specific IgE level in her serum. This, to our knowledge, has not been previously reported in the literature.
Air gun pellets in the sinuses
Authors: O'Connellf J. E. , Turner N. O. , Pahorm A. L. 
Published: November 2007

AbstractThree cases of penetrating sinus injuries due to air gun pellets are presexnted in order to illustrate the potentially serious consequences of air gun injuries. Primary surgery was performed in all cases.The clinical presentation, methods of accurate pre-operative localization and surgery are discussed.
Giant cell reparative granuloma of the cricoid cartilage
Authors: Thomas D. M. , Wilkins M. J. , Witana J. S. , Cook T. , Jefferis A. F. , Walsh-Waring G. P. 
Published: November 2007

AbstractGiant cell reparative granuloma (GCRG) is an uncommon benign lesion which has been reported at several sites in the head and neck. We present a case of a GCRG of the cricoid cartilage not previously described in the literature. It must be differentiated from the brown tumour of hyperparathyroidism and true giant cell tumours of bone. These were excluded on clinical, biochemical, radiological and histological grounds. The lesion responded well to surgical debulking and curettage and the patient remained disease-free 15 months after treatment.
Would day-case adult tonsillectomy be safe?
Authors: Moralee S. J. , Murray J. A. M. 
Published: November 2007

AbstractDay-case surgery is increasing to improve health care efficiency. Adult tonsillectomy is performed on an inpatient basis in the UK because of safety concerns regarding primary haemorrhage. This study aims to investigate the likely safety of day-case tonsillectomy in adults, by defining the incidence and timing of primary haemorrhage and therefore to establish a safe time period for same-day discharge.Prospectively recorded data on 2 157 adult tonsillectomies over a five-year period were reviewed. Serious primary haemorrhage was uncommon (0.8 per cent). The 95 per cent reference range of time to primary haemorrhage was within 0 to 6.8 hours of surgery and the 95 per cent confidence interval (C.I.) of its upper limit was 5.2 to 8.4 hours. The results compare favourably with the UK inpatient and US adult day-case literature.We conclude that day-case tonsillectomy would probably be safe in adults if the patients are discharged after 8.4 hours.
Medullary carcinoma of the thyroid metastatic to the temporal bone
Authors: Redleaf Miriam I. , Bauman Nancy M. , Robinson Robert A. , Gantz Bruce J. 
Published: November 2007

AbstractWe report a case of proven thyroid medullary carcinoma, metastatic to the temporal bone. Review of the otolaryngology literature demonstrates that this is the first such report. The patient presented with symptoms, physical examination, and imaging studies suggestive of a glomus jugulare tumour. The pre-operative diagnosis of metastatic thyroid medullary carcinoma, however, was made, based on a history of medullary carcinoma of the thyroid with previous metastases as well as an elevation in calcitonin levels. Histological examination of the surgical specimen confirmed the diagnosis.
Orbital and skin metastases in a polymorphous low grade adenocarcinoma of the salivary gland
Authors: Thomas K. M. , Cumberworth V. L. , McEwan J. 
Published: November 2007

AbstractWe report the previously undocumented development of an orbital metastasis and skin metastases in a patient with polymorphous low grade adenocarcinoma (PLGA) 15 years after initial presentation. The clinical course, treatment and changing histological features are discussed.
Pre-operative information in mastoidectomy: what about the facial nerve and hearing loss?
Authors: Wormald P. J. 
Published: November 2007

AbstractFacial nerve palsy and hearing impairment are accepted risks of mastoid surgery. However, at present there are no guidelines as to whether a patient must be informed of the potential risk to the facial nerve and hearing during mastoid surgery. Currently the law states that the surgeon should do what a ‘reasonable doctor’ would do under similar circumstances but exactly what this entails is not clear. A recent publication established that 16 per cent of British surgeons did not tell their patients about the risk to the facial nerve and 13 per cent about the risk of hearing loss. A survey of South African surgeons showed a different picture with only 57 per cent of surgeons informing their patients of possible facial nerve injury and 71 per cent about hearing loss. One of the reasons stated was that this information might deter the patient from having a necessary operation. This raises the question of excessive information disclosure and its possible legal consequences if excessive information leads a patient into making an unbalanced judgment owing to his/her lack of medical training, prejudices or personality. In this survey 25 per cent of South African surgeons have had patients refuse surgery after being informed of the risk to facial nerve and hearing. The decision whether to inform the patient about these risks should be individualized for every patient after the surgeon has audited his/her results and assessed the patients prejudices, personality and level of education.