bluuebunny/crossref_metadata_2025_split huggingface dataset:
(080) Psychological Outcomes and Sexual Satisfaction Rates in Males with Phimosis Following the Novoglan Foreskin Extender Treatment
Authors: Chung E , Polikarpov D , Mazure H , James A , Gillatt D 
Published: March 2024

Abstract

Introduction
Phimosis can be associated with sexual dysfunction since it often causes discomfort or pain on erection or during sexual intercourse. While circumcision is routinely advocated in patients with phimosis, many males would prefer conservative treatment and are keen to preserve their foreskins. Novoglan foreskin tissue expander is a non-surgical device that uses a balloon to produce gradual stretching of the phimotic foreskin.

Objective
To assess the impact of phimosis and Novoglan treatment on sexual health and psychological domains.

Methods
Following Institutional Ethics Board approval (HREC/2020/QMS/66682), 20 males with phimosis were recruited across two Australian sites. Inclusion criteria include male aged ≥ 18 years, who has phimosis and normal erectile function, while those with balanoposthitis and/or recurrent UTIs were excluded. All participants received informed consent and completed questionnaires before and after the Novoglan treatment. The questionnaires included questions on pain or discomfort during sexual activity and levels of anxiety or depression. Circumcision was offered to all patients at the start and end of the study period.

Results
Nineteen (95%) patients with phimosis recruited in the Novoglan trial reported pain or discomfort during sexual activity, with one (5%) participant reporting pain or discomfort as severe, while moderate or mild levels were reported by ten (50%) and eight (40%) participants, respectively. The level of pain or discomfort during sexual activity improved significantly after the Novoglan treatment with no patients reporting severe level of pain or discomfort, with most males reporting mild or no pain or discomfort (80%). While all participants documented mild to moderate levels of anxiety or depression prior to treatment, 17 participants (85%) reported no anxiety or depression and only three (15%) men reported a mild degree of psychological distress. None of the participants elected for circumcision.

Conclusions
The Novoglan foreskin tissue expander device significantly improves the psychological outcomes and sexual function in males with phimosis. All patients reported minimal or no pain or discomfort during sexual activity, had minimal or no anxiety or depression related to foreskin issues, and declined circumcision at the end of the study period.

Disclosure
Yes, this is sponsored by industry/sponsor: Novoglan device company.
Clarification: Industry funding only - investigator initiated and executed study.
(112) Penile Rehabilitation by Daily Intake of 5 mg Tadalafil for Erectile Dysfunction After Penile Fracture
Authors: Ragab M W , Fayek S , Ramzy D , Nabil N , Saad H , Labib M , Abo Sief A 
Published: March 2024

Abstract

Introduction
Penile fracture is a rare complication to penile trauma, characterized by a sudden injury of the tunica albuginea of one or both corpora cavernosa of the penis. This commonly occurs during the erect state, when the tunica is thinner and under tension of fully engorged corpora cavernosa. Erectile dysfunction (ED) may occur in up to 12% of these patients due to organic and psychosexual factors including penile fibrosis.

Objective
This study aimed to assess the potential predictors of erectile dysfunction in patients who had penile fracture repair and the role of rehabilitation course of daily tadalafil 5 mg in management of ED following penile fracture.

Methods
From January 2022 to February 2023, 25 patients were included. Patients' baseline data as well as history including the time of presentation, the pattern and length of the tunical tear, and the presence of urethral injury, were obtained. After a week, all patients were followed up on and told to resume intercourse after at least two weeks if their wound had epithelialized. Only patients with a complaint of a weak erection, as determined by the Arabic validated version of the international index of erectile function (ArIIEF-5), were started on daily tadalafil 5 mg as a penile rehabilitation for at least one month, or until they regained their normal erection. The Hospital Anxiety and Depression Scale (HADS) was used for assessing patients. Patients with confounding disease as metabolic syndrome or mental illness were eliminated.

Results
Significant indicators predicting erectile dysfunction, according to the multiple logistic regression model, are the patients' age and the length of the tunical tear. A 1% increase in age was linked with a 73.6% rise in the probability of erectile dysfunction (p = 0.046), and a 1 cm increase in tunical tear length was associated with a 20.04 times increased risk of erectile dysfunction (p = 0.04). With a mean score of 20 on the Arabic-approved version of the internal index of erectile function, 5 of 9 patients with erectile dysfunction (55%) had improved erections after one month of penile rehabilitation, while only 4 of 9 patients (44%) required an additional month of treatment.

Conclusions
We propose that patients with penile fractur be counselled about erectile dysfunction and begin penile rehabilitation as soon as possible following repair to regain a normal erection.

Disclosure
No.
(114) A Comparative Meta-Analysis of Revision Strategies for Malfunctioning Inflatable Penile Prosthesis: Partial vs Complete Component Replacement With or Without Retained Reservoir
Authors: El-Achkar A , Khalaf Alla K , Nguyen T , Mahdi M , Wang R 
Published: March 2024

Abstract

Introduction
In cases of non-infected malfunctioning Inflatable penile prosthesis (IPP) device, surgeon often opt to exchange all the device rather than the defective component for fear of increased infection rate and future mechanical dysfunction.

Objective
To assess whether partial component exchange of IPP device has comparable outcomes to complete explant and replacement of IPP device with or without retained reservoir.

Methods
A meta-analysis was completed in line with PRISMA 2020 and AMSTAR guidelines. A comprehensive search was done on MEDLINE (OVID), PubMed, and Cochrane Library electronic databases from their inceptions until May 2023, identifying studies that reported on outcomes and complications of revision surgery for non-infected malfunctioning IPP device. Three groups were compared: the first group underwent a single or two-component exchange, the second group had a complete explant replacement of the entire device, and the third group had replacement of all components with a drained and retained primary reservoir.

Results
A total of 9 articles were included in the analysis. 12,152 patients had complete replacement of their device, 128 had partial exchange of their device and 151 patients had “drained and retained” reservoir following revision. The mean age was similar among the 3 groups between 62–68 years. The median follows up time ranged between 12 and 79 months. Partial component ex change had a higher rate of mechanical failure 10.3% versus 1.3% and 2.3 % (p=0.03) for complete and “drain and retain” groups respectively. (Figure 1) Similarly, partial component exchange had higher peri-operative complications at 21.2% compared to complete replacement group 9.5% and “drain and retain” group 14.5% (p=0.022). However, the infection rate was similar among the three groups, 7.7%, 2.7% and 3.3% respectively (p= 0.301). (Figure 2)

Conclusions
Partial component exchange during IPP revision has higher rates of perioperative complication and future mechanical failure but has similar rate of infection compared to complete component replacement with or without “drain and retain” of original reservoir.

Disclosure
No.
(129) Penile Girth Enhancement Using UroFill™: The Brazilian Experience
Authors: Cavalcanti Filho M T , Ramalho G , Monteiro L , Lacerda D , Braga G 
Published: March 2024

Abstract

Introduction
Demands for penile girth enhancement are increasing. UroFill™ is the innovative approach that offers non-surgical and reproducible penile girth enhancement.

Objective
To demonstrate the penile girth before and after the application of hyaluronic acid with the UroFill™ technique

Methods
A retrospective, single-center study included men who sought private care to realize penile girth enhancement using UroFill™ technique from April to June 2023. All patients signed an informed consent form. Excluded men with dysmorphophobia, active inflammatory-infectious genital lesion, and prior application of another filler. Penile girth was measured with a tape measure at baseline and after 21 days.

Results
21 patients were included in this analysis. Mean injected volume was 5.81ml. Compared a mean with a basal girth of 9.11±1.1cm and after 1 application 10.85±0.9cm and the Test t result was significant p &lt; 0.001. There were no inflammatory signs or serious adverse reactions in all cases, and no patient requested a reversal of the procedure.

Conclusions
This study demonstrates the increase in penile girth after just one application of hyaluronic acid using the Urofill technique. In addition, we did not find any cases of complications in the evaluated patients, which suggests a safe procedure.

Disclosure
No.
(133) Non-Occupational SCC of the Scrotum; Case Presentation and Management
Authors: El-Bahnasawy M , Alanazi M , Talahmeh G , Abolhasan A , Kamal A 
Published: March 2024

Abstract

Introduction
Although the incidence of scrotal malignancies is extremely low Squamous cell carcinoma (SCC) is the most common scrotal malignancy. Its overall annual incidence is approximately 1.5 per 1,000,000 persons in Western countries. It was first linked to the chronic irritation of scrotal skin by the effect of soot in occurring in chimney sweepers hence known as the first described occupational disease. Occupational scrotal SCC was also later described in association with other occupations with chronic carcinogen exposure including cotton mule spinners, paraffin and tar workers, creosote workers, shale oil workers, lathe workers, pitch workers and machine tool setters and operators. Currently most cases result from poor hygiene and chronic inflammation

Objective
Herein we present a very rare case of SCC of the scrotum referred to us from Dermatology department

Methods
This 55 years old male patient was referred from dermatology department. He had no underlying occupational hazard. He has been treated for several months of itchy inflammation of the scrotumfor 6 months. Scrotal punch biosy showed moderately differentiated SCC. Clinically there was malignant scrotal ulcer of 4x3 cm with no palpable inguinal lymph nodes. CT staging confirmed localized tumor with no LN or metastatic deposits. Complete excision with 2 cm safety margin confirmed to be negative by frozen section. Final histopathology come to be moderately differentiated SCC pT2Nx. All margins and underlying Dartos were free of tumor infiltration.

Results
Complete excision could be achieved with intra-operative negative frozen section. Uneventful post-operative course with complete healing of scrotal wound.

Conclusions
Although rare, scrotal SCC continues to be serious urogenital malignancy which should be suspected even in the absence of occupational exposure. Cooperation and awareness of Dermatologists is important for early detection and management of such rare malignancy. Complete excision with safety margin is usually sufficient for cure. Inguinal Lymphadenectomy is indicated if grossly infiltrated

Disclosure
No.
(136) Sexual Behavior among Asexual Men and Women in the Czech Population
Authors: Krejčová C , Klapilová K , Bártová K 
Published: March 2024

Abstract

Introduction
Asexuality is usually defined as a lack of sexual attraction to others; however, asexuals may engage in sexual activity. Previous research has shown that asexuals are less likely to engage in sexual intercourse and masturbation than allosexuals. But information about detailed aspects of sexual behavior among asexuals is still scattered.

Objectives
The main aim of this study was to map the sexual behavior of asexual men and women. In addition, the usage and pleasurability of various sex positions in asexuals were explored.

Methods
Participants were recruited in 2020 via a sociodemographic agency using computer-assisted web interviewing software. Stratified random sampling with quotas on Czech nationality, region, size of the place of residence, sex, age, and education was applied. A representative sample of 1,616 adult men (n = 806; 21–85 years; mage = 50.65; SD = 15.52) and women (n = 810; 20–91 years; mage = 50,62; SD = 16.15) answered questions about selected dimensions of sexual behavior in the last year.

Results
Approximately 2.1 % (n = 17) of men and 1.6 % (n = 13) of women indicated they were asexual. Preliminary results showed that asexual women had more sexual intercourse per month in the last year (7–10 vs. 4–6 occasions) compared to asexual men. Asexual women and men had the same average number of orgasms per month achieved during partner sexual activities with a long-term partner in the last year (2–3x). Asexual men had a stronger desire for sexual activity with a partner per month (7–10x vs. 4–6x), a higher number of masturbations per month and orgasms achieved during masturbation (2–3x vs. none), and a higher number of searches for erotic/pornographic materials per month in the last year (2–3x vs. none). Asexual women expressed a higher preference for sexual activities with a partner, whereas asexual men expressed a similar preference for sexual activities with a partner and masturbation. Based on median frequencies of sexual positions used in the last year, asexual women reported engaging in most penile-vaginal sexual positions (1–2x) but not sexual positions with oral-genital contact. Among asexual men, face-to-face/male above was the only reported sexual position used in the last year (1–2x). Asexual women and men reported face-to-face/male above, face-to-face/female above, and kneeling/rear entry as the most pleasurable sexual positions.

Conclusion
Consistent with previous research, we found that asexuals may engage in sexual intercourse and masturbation. Asexual women were more likely to engage in sexual intercourse with various penile-vaginal sexual positions. In contrast, asexual men experienced stronger sexual desire and were more likely to engage in masturbation. No discrepancy was found in the rated pleasurability of several sexual positions. Thus, our results suggest that asexual women may prefer sexual activities with a partner, whereas asexual men may prefer autosexual activities.

Disclosure
No.
(148) The Prevalence and Genotype Distribution of Human Papillomaviruses in Korean
Authors: Moon D G , Ahn S T , Lee H S , Cho S B , Moon S J , Hwang W K , Kim H J 
Published: March 2024

Abstract

Introduction
Human papillomavirus (HPV) prevalence and genotype distribution are different between various nations and regions. Additionally, previous studies have mainly focused on HPV infection in western female and epidemiological studies of HPV infection in regional populations have been rarely reported. The lack of information on the HPV genotype distribution of the regional population in each individual country or region raises questions about the effectiveness of the current 9-valent vaccination.

Objective
To assess the prevalence and genotype of HPV(+) Korean and to know whether currently available 9-valent vaccine can cover the most prevalent and high risk genotype as HPV vaccine in Korean.

Methods
Between January 2014 to June 2022, samples of 44,065 men (Study I, M) and 564,499 females (Study II, F), who were volunteered for testing or recommended by a clinician, were tested for HPV detection and genotyping. Samples were collected swabs from the pap smear test. HPV detection and typing were conducted using the Anyplex™ II HPV 28 Detection system, which detects 19 high-risk (HR) HPVs and 9 low-risk (LR) HPVs.

Results
In Study I & Study II, overall prevalence were 59.7% (M), 44.3%(F), prevalence of HR were 30.6%(M), 37.5%(F) and LR HPVs were 50.1%(M), 18.3%(F), respectively. Overall HPV prevalence was higher in teens (34.1% in M and 58.3% in F) and 20s (33.8% in M and 51.9% in F) with age [Table 1]. The most prevalent genotypes of HR were 16 (5.2%), 53 (4.6%), 51 (4.2%), 52 (3.8%), 58 (3.7%), 39(3.6%) and 66(3.4%) in Study I. In Study II of Female, the most prevalent genotypes of HR were 52 (7.1%), 53 (6.2%), 58 (5.0%), 68 (4.8%), and 16 (4.3%). In Study I of 26,299 men with HPV infection, 9,259 (35.2%) had a genotype with HR; 53 (4.6%), 51 (4.2%), 39(3.6%) and 66(3.4%), which could not prevented by the 9-valent vaccine. In Study II of 211,883 females with HPV infection, 72,252 (34.1%) had a genotype with HR, 68 (4.8%), 51 (4.1%), 39 (3.8%), and 56 (3.7%) which could not be prevented by the 9-valent vaccine.

Conclusions
In this study, Korea male and female aged under 30 years showed a high prevalence of HR HPVs. In both Male and Female groups, a significant number of HR HPVs infections were not prevented by 9-valent vaccine. Based on this result, it is necessary to develop nation-specific HPV vaccination for Korean. Further, this approach can be applied in other countries.

Disclosure
No.
(151) Knowledge, Attitude, and Practice of Nursing and Midwifery Students Regarding Sexually Transmitted Infections
Authors: Souayeh N , Bettaieb H , Rouis H , Mbarki C , Hsayaoui N 
Published: March 2024

Abstract

Introduction
Sexually transmitted infections (STIs) are a global health problem. Nursing and obstetrics students are the future workers whose role in health education and promotion is undeniable. Hence we became interested in evaluating their knowledge of STIs.

Objective
The aim of our study was to assess the knowledge, attitude, and practice of nursing and midwifery students regarding sexually transmitted diseases.

Methods
This was a prospective, cross-sectional, quantitative, and descriptive study, conducted in the Higher Institute of Nursing Sciences of Tunis (ISSIT) and the Higher Institute of Health Sciences and Techniques of Tunis (ESSTST) over the period of to months (March 1st, 2022 to April 30, 2022). The target population of our study included 568 students. The information was collected via a self-administered questionnaire.

Results
Our study population sample was mainly composed of women (72%) versus 28% men. The average age of our sample was 21 years old. The majority of students (95%) have already heard of STIs. The main source of information was the academic background of these students (79%), followed by the media (15%) and only 1% comes from the family circle. Students rated their knowledge as fairly good and good in 37% and 34% of cases, respectively. Only 5% admitted having very good knowledge and 2% with zero knowledge. For their knowledge of the modes of transmission of STIs: 98.4% retained vaginal penetration, 69.1% for anal penetration against 40.7% for oral sex. The best-known germ was the human immunodeficiency virus (HIV) (87.8%) followed closely by syphilis (82.9%). The least known agent was Neisseria Gonorrhoeae (Gonococcus), identified only in 28.4% of cases. 65% of the students recognized syphilis as a bacterial infection. However, 34.1% of students in the sample did not know that it can be associated with HIV infection. Most students (52.8%) had no information regarding HPV infection and only a minority of 18.7% knew that there is an HPV vaccine. 7% already had sex and the medium age of their first sexual intercourse was 18, With an average of 1.33 partners during the last 12 months. Only 2% of them had used a condom during their first sexual intercourse with a new partner. 43%had justified the nonuse of condoms with decreased feelings of pleasure, 29% get embarrassed to purchase it, 14%had some difficulties using it, and 14% did not use a condom because they simply wanted to get pregnant. 75%had the intention to use a condom during their first sexual intercourse while 25% did not.

Conclusions
The knowledge of health students regarding sexually transmitted infections needs a boost in order to improve the involvement of awareness of the whole population. Besides, they are not taking the necessary measures to avoid sexually transmitted infections for multiple reasons and the lack of knowledge might be the main cause.

Disclosure
No.
(154) Corporal Tissue Ingrowth: A Rare but Operable Challenge in Revision Surgery for Inflatable Penile Prosthesis
Authors: Khalaf Alla K , Calopedos R , Mehr J , Wang R 
Published: March 2024

Abstract

Introduction
Corporal tissue ingrowth into previously implanted cylinder is a rare but possible issue encountered during penile prosthesis (PP) revision surgery. To prevent cylinder aneurysms, a middle layer of woven and expandable polypropylene-like material was incorporated into the implant design in 1987. While the outer silicone layer usually prevents its contact with tissue, in cases of ruptured cylinders, there is a risk of cavernous ingrowth into the exposed woven layer. Collagen deposition within the inflammatory tongue of tissue can lead to significant difficulty in implant removal. Having a degree of suspicion about this phenomenon is important, especially as an implant may remain somewhat functional if the inner silicone layer remains intact. If encountered, its recognition is paramount in triggering operative countermeasures. To our knowledge, this is the only contemporary and second case series describing this phenomenon in English literature.

Objective
To highlight the existence of this difficult phenomenon in revision surgery and demonstrate our approach.

Methods
We report 3 patients over the past 3 years who underwent complex penile revision surgery. All had AMS penile implantation 10–15 years prior and presented with inability to inflate device. Each case began routinely through a vertical penoscrotal incision; however, the stuck cylinders were unable to be removed through the traditional corporotomy. Penoscrotal incision and corporotomy were extended until the location of ingrowth was identified. A combination of sharp and blunt dissection was required to liberate the cylinder from the surrounding corporal tissue. Care was taken to maintain a plane just outside the ruptured cylinder to prevent more proximal or distal injury to the tunica albuginea. Once liberated and new device implanted, corpora are closed in the usual fashion without the need for elaborate tunica albuginea reconstruction.

Results
All 3 patients had successful revision of impacted cylinder from the corpora through extension of the vertical penoscrotal incision. No secondary distal incision was necessary in these cases. Patients were followed for 6–12 months in which time all prosthesis remained functional and no deviation from the usual post-operative course was encountered.

Conclusions
Implanters should not shy away from maximizing exposure if ingrowth is suspected. The vertical penoscrotal incision was a versatile approach that could be easily extended and should be considered for suspected complex revision surgery. Furthermore, this phenomenon also adds credence to early revision surgery in the cases of device malfunction from suspected cylinder rupture. Despite the difficulty this issue poses, corporal tissue readily integrates into porous synthetic materials. This ability may be useful in future device development in the tissue engineering space.

Disclosure
No.