bluuebunny/crossref_metadata_2025_split huggingface dataset:
Inhibitory effects and mechanisms of cinnamaldehyde against Fusarium oxysporum, a serious pathogen in potatoes
Authors: Zhang Chunlin , Liu Hongling , Wang Xue , Long Xueyan , Huang Airong , Zhang Jiaomei , Geng Jiahui , Yang Liting , Huang Zhenlin , Dong Pan , Shi Lei 
Published: March 2024

AbstractBACKGROUNDPotatoes, a major economic crop, are significantly impacted by Fusarium dry rot, a prevalent postharvest disease. Despite the broad‐spectrum antimicrobial properties of cinnamaldehyde, a naturally‐derived plant substance, its efficacy against the causal pathogen of potato dry rot (Fusarium oxysporum) and the underlying mechanisms have not been extensively studied.RESULTSOur study demonstrates that cinnamaldehyde effectively inhibits the growth of Fusarium oxysporum, the pathogen responsible for potato dry rot, and increases its sensitivity to environmental stress factors such as extreme temperatures and high salt stress. Treatment with cinnamaldehyde results in altered fungal mycelium morphology, compromised cell wall stability, and disrupted cell membrane integrity, thereby reducing spore viability. Specifically, it interferes with the cell membrane and cell wall structures of the fungus, potentially disrupting fungal growth by modulating signaling pathways involved in cell wall maintenance, chitin metabolism, and GPI‐anchored protein function. Notably, we show that cinnamaldehyde induces a form of regulated cell death in F. oxysporum, which is characterized not as typical apoptosis, as evidenced by Annexin V negative staining. However, the specific cell death type and underlying mechanism still needed to be further explored.CONCLUSIONCinnamaldehyde, an environmentally friendly plant‐based active compound, exhibits strong inhibitory effects on F. oxysporum, indicating its potential use in the prevention and control strategies for potato dry rot. This research contributes to the understanding of novel antifungal mechanisms and offers promising insights into eco‐friendly alternatives for managing this economically significant postharvest disease. © 2024 Society of Chemical Industry.
Mycorrhiza‐induced resistance in citrus against Tetranychus urticae is plant species dependent and inversely correlated to basal immunity
Authors: Manresa‐Grao María , Pastor Victoria , Sánchez‐Bel Paloma , Cruz Ana , Cerezo Miguel , Jaques Josep A , Flors Víctor 
Published: March 2024

AbstractBACKGROUNDMycorrhizal plants show enhanced resistance to biotic stresses, but few studies have addressed mycorrhiza‐induced resistance (MIR) against biotic challenges in woody plants, particularly citrus. Here we present a comparative study of two citrus species, Citrus aurantium, which is resistant to Tetranychus urticae, and Citrus reshni, which is highly susceptible to T. urticae. Although both mycorrhizal species are protected in locally infested leaves, they show very distinct responses to MIR.RESULTSPrevious studies have indicated that C. aurantium is insensitive to MIR in systemic tissues and MIR‐triggered antixenosis. Conversely, C. reshni is highly responsive to MIR which triggers local, systemic and indirect defense, and antixenosis against the pest. Transcriptional, hormonal and inhibition assays in C. reshni indicated the regulation of jasmonic acid (JA)‐ and abscisic acid‐dependent responses in MIR. The phytohormone jasmonic acid isoleucine (JA‐Ile) and the JA biosynthesis gene LOX2 are primed at early timepoints. Evidence indicates a metabolic flux from phenylpropanoids to specific flavones that are primed at 24 h post infestation (hpi). MIR also triggers the priming of naringenin in mycorrhizal C. reshni, which shows a strong correlation with several flavones and JA‐Ile that over‐accumulate in mycorrhizal plants. Treatment with an inhibitor of phenylpropanoid biosynthesis C4H enzyme impaired resistance and reduced the symbiosis, demonstrating that phenylpropanoids and derivatives mediate MIR in C. reshni.CONCLUSIONMIR's effectiveness is inversely correlated to basal immunity in different citrus species, and provides multifaceted protection against T. urticae in susceptible C. reshni, activating rapid local and systemic defenses that are mainly regulated by the accumulation of specific flavones and priming of JA‐dependent responses. © 2024 The Authors. Pest Management Science published by John Wiley & Sons Ltd on behalf of Society of Chemical Industry.
Collagen Tubular Airway‐on‐Chip for Extended Epithelial Culture and Investigation of Ventilation Dynamics
Authors: Gao Wuyang , Kanagarajah Kayshani R. , Graham Emma , Soon Kayla , Veres Teodor , Moraes Theo J. , Bear Christine E. , Veldhuizen Ruud A. , Wong Amy P. , Günther Axel 
Published: March 2024

AbstractThe lower respiratory tract is a hierarchical network of compliant tubular structures that are made from extracellular matrix proteins with a wall lined by an epithelium. While microfluidic airway‐on‐a‐chip models incorporate the effects of shear and stretch on the epithelium, week‐long air‐liquid‐interface culture at physiological shear stresses, the circular cross‐section, and compliance of native airway walls have yet to be recapitulated. To overcome these limitations, a collagen tube‐based airway model is presented. The lumen is lined with a confluent epithelium during two‐week continuous perfusion with warm, humid air while presenting culture medium from the outside and compensating for evaporation. The model recapitulates human small airways in extracellular matrix composition and mechanical microenvironment, allowing for the first time dynamic studies of elastocapillary phenomena associated with regular breathing and mechanical ventilation, as well as their impacts on the epithelium. A case study reveales increasing damage to the epithelium during repetitive collapse and reopening cycles as opposed to overdistension, suggesting expiratory flow resistance to reduce atelectasis. The model is expected to promote systematic comparisons between different clinically used ventilation strategies and, more broadly, to enhance human organ‐on‐a‐chip platforms for a variety of tubular tissues.
Fabrication of Single‐Crystal Violet Phosphorus Flakes For Ultrasensitive Photodetection
Authors: Da Yumin , Zhou Yongheng , Zhang Shuai , Li Yang , Jiang Tongtong , Zhu Wenting , Chu Paul K. , Yu Xue‐Feng , Chen Xiaolong , Wang Jiahong 
Published: March 2024

AbstractViolet phosphorus (VP) has attracted a lot of attention for its unique physicochemical properties and emerging potential in photoelectronic applications. Although VP has a van der Waals (vdW) structure similar to that of other 2D semiconductors, direct synthesis of VP on a substrate is still challenging. Moreover, optoelectronic devices composed of transfer‐free VP flakes have not been demonstrated. Herein, a bismuth‐assisted vapor phase transport technique is designed to grow uniform single‐crystal VP flakes on the SiO2/Si substrate directly. The size of the crystalline VP flakes is an order of magnitude larger than that of previous liquid‐exfoliated samples. The photodetector fabricated with the VP flakes shows a high responsivity of 12.5 A W−1 and response/recovery time of 3.82/3.03 ms upon exposure to 532 nm light. Furthermore, the photodetector shows a small dark current (<1 pA) that is beneficial to high‐sensitivity photodetection. As a result, the detectivity is 1.38 × 1013 Jones that is comparable with that of the vdW p–n heterojunction detector. The results reveal the great potential of VP in optoelectronic devices as well as the CVT technique for the growth of single‐crystal semiconductor thin films.
Ru Regulated Electronic Structure of PdxCuy Nanosheets for Efficient Hydrogen Evolution Reaction in Wide pH Range
Authors: Wang Jigang , Zhang Guangyang , Liu Huan , Wang Likai , Li Zhongfang 
Published: March 2024

AbstractThe development of highly effective catalysts for hydrogen evolution reaction (HER) in a wide pH range is crucial for the sustainable utilization of green energy utilization, while the slow kinetic reaction rate severely hinders the progress of HER. Herein, the reaction kinetic issue is solved by adjusting the electronic structure of the Ru/PdxCuy catalysts. The champion catalyst displays a remarkable performance for HER with the ultralow overpotential (27, 28, and 97 mV) in 1.0 m KOH, 0.5 m H2SO4, and 1.0 m PBS at 10 mA cm−2 and high the mass activity (3036 A g−1), respectively, superior to those of commercial Pt/C benchmarks and most of reported electrocatalysts, mainly due to its low reaction activation energy. Density functional theory (DFT) calculations indicate that Ru doping contributes an electron‐deficient 3d band, which promotes water adsorption. Additionally, this also leads to an upward shift of the d‐band center of Pd and a downward shift of the d‐band center of Cu, further optimizing the adsorption/dissociation of H2O and H*. Results from this work may provide an insight into the design and synthesis of high‐performance pH‐universal HER electrocatalysts.
NIR‐Triggered Multifunctional NO Nanoplatform for Conquering Thermal Resistance in Biofilms
Authors: Zhou Bingshuai , Dong Biao , Hu Songtao , Liu Wei , Sun Liheng , Xu Lin , Bai Xue , Wang Lin , Qi Manlin , Song Hongwei 
Published: March 2024

AbstractPhotothermal treatment (PTT) has emerged as a promising avenue for biofilm elimination, yet its potential drawbacks, such as local hyperpyrexia and bacterial heat resistance, have posed challenges. To address these concerns, an innovative nanoplatform (Au@mSiO2‐arg/ICG) is devised that integrates phototherapeutic and gas therapeutic functionalities. This multifaceted nanoplatform is composed of mesoporous silica‐coated Au nanorods (Au@mSiO2), supplemented with l‐arginine (l‐arg) and indocyanine green (ICG), and is engineered for mild temperature PTT aimed at biofilm eradication. Au@mSiO2‐arg/ICG nanoparticles (NPs) show excellent antibacterial effects through the generation of nitric oxide (NO) gas, heat, and reactive oxygen species (ROS) under 808 nm light irradiation. The ROS generated by ICG initiates a cascade reaction with l‐arg, ultimately yielding NO gas molecules. This localized release of NO not only effectively curbs the expression of heat shock proteins 70 mitigating bacterial thermoresistance, but also reduces extracellular polymeric substance allowing better penetration of the therapeutic agents. Furthermore, this nanoplatform achieves an outstanding biofilm elimination rate of over 99% in an abscess model under 808 nm light irradiation (0.8 W·cm−2), thereby establishing its potential as a dependable strategy for NO‐enhanced mild PTT and antibacterial photodynamic therapy (aPDT) in clinical settings.
Strain Engineering: Perfecting Freestanding Perovskite Oxide Fabrication
Authors: Yun Shinhee , le Cozannet Thomas Emil , Christoffersen Christina Høgfeldt , Brand Eric , Jespersen Thomas Sand , Pryds Nini 
Published: March 2024

AbstractFreestanding oxide membranes provide a promising path for integrating devices on silicon and flexible platforms. To ensure optimal device performance, these membranes must be of high crystal quality, stoichiometric, and their morphology free from cracks and wrinkles. Often, layers transferred on substrates show wrinkles and cracks due to a lattice relaxation from an epitaxial mismatch. Doping the sacrificial layer of Sr3Al2O6 (SAO) with Ca or Ba offers a promising solution to overcome these challenges, yet its effects remain critically underexplored. A systematic study of doping Ca into SAO is presented, optimizing the pulsed laser deposition (PLD) conditions, and adjusting the supporting polymer type and thickness, demonstrating that strain engineering can effectively eliminate these imperfections. Using SrTiO3 as a case study, it is found that Ca1.5Sr1.5Al2O6 offers a near‐perfect match and a defect‐free freestanding membrane. This approach, using the water‐soluble Bax/CaxSr3‐xAl2O6 family, paves the way for producing high‐quality, large freestanding membranes for functional oxide devices.
Photocatalytic Optical Hollow Fiber with Enhanced Visible‐light‐driven CO2 Reduction
Authors: Chen Jie , Liu Yang , Xie Quanhua , He Yuanyuan , Zhong Dengjie , Chang Haixing , Ho Shih‐Hsin , Zhong Nianbing 
Published: March 2024

AbstractA visible‐light‐driven CO2 reduction optical fiber is fabricated using graphene‐like nitrogen‐doped composites and hollow quartz optical fibers to achieve enhanced activity, selectivity, and light utilization for CO2 photoreduction. The composites are synthesized from a lead‐based metal–organic framework (TMOF‐10‐NH2) and g‐C3N4 nanosheet (CNNS) via electrostatic self‐assembly. The TMOF‐10‐NH2/g‐C3N4 (TMOF/CNNS) photocatalyst with an S‐type heterojunction is coated on optical fiber. The TMOF/CNNS coating, which has a bandgap energy of 2.15 eV, has good photoinduced capability at the coating interfaces, high photogenerated electron–hole pair yield, and high charge transfer rate. The conduction band potential of the TMOF/CNNS coating is more negative than that for CO2 reduction. Moreover, TMOF facilitates the CO desorption on its surface, thereby improving the selectivity for CO production. High CO2 photoreduction and selectivity for CO production is demonstrated by the TMOF/CNNS‐coated optical fiber with the cladding/core diameter of 2000/1000 µm, 10 wt% TMOF in CNNS, coating thickness of 25 µm, initial CO2 concentration of 90 vol%, and relative humidity of 88% RH under the excitation wavelength of 380–780 nm. Overall, the photocatalytic hollow optical fiber developed herein provides an effective and efficient approach for the enhancement of light utilization efficiency of photocatalysts and selective CO2 reduction.
Interface and Morphology Engineered Amorphous Si for Ultrafast Electrochemical Lithium Storage
Authors: Sonia Farjana J. , Haider Golam , Ghosh Subrata , Müller Martin , Volochanskyi Oleksandr , Bouša Milan , Plšek Jan , Kamruddin Mohammed , Fejfar Antonín , Kalbáč Martin , Frank Otakar 
Published: March 2024

AbstractUltrafast high‐capacity lithium‐ion batteries are extremely desirable for portable electronic devices, where Si is the most promising alternative to the conventional graphite anode due to its very high theoretical capacity. However, the low electronic conductivity and poor Li‐diffusivity limit its rate capability. Moreover, high volume expansion/contraction upon Li‐intake/uptake causes severe pulverization of the electrode, leading to drastic capacity fading. Here, interface and morphology‐engineered amorphous Si matrix is being reported utilizing a few‐layer vertical graphene (VG) buffer layer to retain high capacity at both slow and fast (dis)charging rates. The flexible mechanical support of VG due to the van‐der‐Waals interaction between the graphene layers, the weak adhesion between Si and graphene, and the highly porous geometry mitigated stress, while the three‐dimensional mass loading enhanced specific capacity. Additionally, the high electronic conductivity of VG boosted rate‐capability, resulting in a reversible gravimetric capacity of ≈1270 mAh g−1 (areal capacity of ≈37 µAh cm−2) even after 100 cycles at an ultrafast cycling rate of 20C, which provides a fascinating way for conductivity and stress management to obtain high‐performance storage devices.
Multifunctional Heterostructured Fe3O4‐FeTe@MCM Electrocatalyst Enabling High‐Performance Practical Lithium‐Sulfur Batteries Via Built‐in Electric Field
Authors: Gao Yi‐bo , Liu Guo‐qiang , Geng Hai‐tao , He Xin , Na Xiang‐ming , Liu Fu‐shuang , Li Bao , Wang Bao 
Published: March 2024

AbstractThe development of capable of simultaneously modulating the sluggish electrochemical kinetics, shuttle effect, and lithium dendrite growth is a promising strategy for the commercialization of lithium‐sulfur batteries. Consequently, an elaborate preparation method is employed to create a host material consisting of multi‐channel carbon microspheres (MCM) containing highly dispersed heterostructure Fe3O4‐FeTe nanoparticles. The Fe3O4‐FeTe@MCM exhibits a spontaneous built‐in electric field (BIEF) and possesses both lithophilic and sulfophilic sites, rendering it an appropriate host material for both positive and negative electrodes. Experimental and theoretical results reveal that the existence of spontaneous BIEF leads to interfacial charge redistribution, resulting in moderate polysulfide adsorption which facilitates the transfer of polysulfides and diffusion of electrons at heterogeneous interfaces. Furthermore, the reduced conversion energy barriers enhanced the catalytic activity of Fe3O4‐FeTe@MCM for expediting the bidirectional sulfur conversion. Moreover, regulated Li deposition behavior is realized because of its high conductivity and remarkable lithiophilicity. Consequently, the battery exhibited long‐term stability for 500 cycles with 0.06% capacity decay per cycle at 5 C, and a large areal capacity of 7.3 mAh cm−2 (sulfur loading: 9.73 mg cm−2) at 0.1 C. This study provides a novel strategy for the rational fabrication of heterostructure hosts for practical Li‐S batteries.
Reticular Heterojunction for Organic Photoelectrochemical Transistor Detection of Neuron‐Specific Enolase
Authors: Hou Lu , Gao Yuan , Kong Fen‐Ying , Wang Ze‐Chen , Lin Lang , Han De‐Man , Chen Feng‐Zao 
Published: March 2024

AbstractReticular heterojunctions on the basis of metal–organic frameworks (MOFs) and covalent organic frameworks (COFs) have sparked considerable interest in recent research endeavors, which nevertheless have seldom been studied in optoelectronic biosensing. In this work, its utilization for organic photoelectrochemical transistor (OPECT) detection of the important cancer biomarker of neuron‐specific enolase (NSE) is reported. A MOF@COF@CdS quantum dots (QDs) heterojunction is rationally designed to serve as the photogating module against the polymeric channel. Linking with a sandwich complexing event, target‐dependent alternation of the photogate is achieved, leading to the changed photoelectric conversion efficiency as indicated by the amplified OPECT signals. The proposed assay demonstrates good analytical performance in detecting NSE, featuring a linear detection range from 0.1 pg mL−1 to 100 ng mL−1, with a detection limit of 0.033 pg mL−1.
Arming Amorphous NiMoO4 on Nickel Phosphide Enables Highly Stable Alkaline Seawater Oxidation
Authors: Guo Xiankun , He Xun , Liu Xuwei , Sun Shengjun , Sun Hang , Dong Kai , Li Tengyue , Yao Yongchao , Xie Ting , Zheng Dongdong , Luo Yongsong , Chen Jie , Liu Qian , Li Luming , Chu Wei , Jiang Zhenju , Sun Xuping , Tang Bo 
Published: March 2024

AbstractSeawater electrolysis holds tremendous promise for the generation of green hydrogen (H2). However, the system of seawater‐to‐H2 faces significant hurdles, primarily due to the corrosive effects of chlorine compounds, which can cause severe anodic deterioration. Here, a nickel phosphide nanosheet array with amorphous NiMoO4 layer on Ni foam (Ni2P@NiMoO4/NF) is reported as a highly efficient and stable electrocatalyst for oxygen evolution reaction (OER) in alkaline seawater. Such Ni2P@NiMoO4/NF requires overpotentials of just 343 and 370 mV to achieve industrial‐level current densities of 500 and 1000 mA cm−2, respectively, surpassing that of Ni2P/NF (470 and 555 mV). Furthermore, it maintains consistent electrolysis for over 500 h, a significant improvement compared to that of Ni2P/NF (120 h) and Ni(OH)2/NF (65 h). Electrochemical in situ Raman spectroscopy, stability testing, and chloride extraction analysis reveal that is situ formed MoO42−/PO43− from Ni2P@NiMoO4 during the OER test to the electrode surface, thus effectively repelling Cl− and hindering the formation of harmful ClO−.
Nature‐Inspired Molecular‐Crowding Enabling Wide‐Humidity Range Applicable, Anti‐Freezing, and Robust Zwitterionic Hydrogels for On‐Skin Electronics
Authors: Gong Min , Wang Xiaobo , Wu Zhen , Yue Liancong , Chen Qiuji , Li Hejian , Lin Xiang , Zhang Liang , Wang Dongrui 
Published: March 2024

AbstractHydrogels are currently in the limelight for applications in soft electronics but they suffer from the tendency to lose water or freeze when exposed to dry environments or low temperatures. Molecular crowding is a prevalent occurrence in living cells, in which molecular crowding agents modify the hydrogen bonding structure, causing a significant reduction in water activity. Here, a wide‐humidity range applicable, anti‐freezing, and robust hydrogel is developed through the incorporation of natural amino acid proline (Pro) and conductive MXene into polyvinyl alcohol (PVA) hydrogel networks. Theoretical calculations reveal that Pro can transform “free water” into “locked water” via the molecular‐crowding effect, thereby suppressing water evaporation and ice forming. Accordingly, the prepared hydrogel exhibits high water retention capability, with 77% and 55% being preserved after exposure to 20 °C, 28% relative humidity (RH) and 35 °C, 90% RH for 12 h. Meanwhile, Pro lowers the freezing temperature of the hydrogel to 34 °C and enhances its stretchability and strength. Finally, the PVA/Pro/MXene hydrogels are assembled as multifunctional on‐skin strain sensors and conductive electrodes to monitor human motions and detect tiny electrophysiological signals. Collectively, this work provides a molecular crowding strategy that will motivate researchers to develop more advanced hydrogels for versatile applications.
A Targeted and Responsive Nanoprodrug Delivery System for Synergistic Glioma Chemotherapy
Authors: Zhuo Weiling , Wang Wanyu , Zhou Wenjie , Duan Zhongxin , He Shi , Zhang Xifeng , Yi Linbin , Zhang Rui , Guo Anjie , Gou Xinyu , Chen Junli , Huang Ning , Sun Xiaodong , Qian Zhiyong , Wang Xiang , Gao Xiang 
Published: March 2024

AbstractDoxorubicin (DOX) is widely used as a chemotherapeutic agent for both hematologic and solid tumors and is a reasonable candidate for glioma treatment. However, its effectiveness is hindered by significant toxicity and drug resistance. Moreover, the presence of the blood–brain barrier (BBB) brings a crucial challenge to glioma therapy. In response, a GSH‐responsive and actively targeted nanoprodrug delivery system (cRGD/PSDOX‐Cur@NPs) are developed. In this system, a disulfide bond‐bridged DOX prodrug (PEG‐SS‐DOX) is designed to release specifically in the high glutathione (GSH) tumor environment, markedly reducing the cardiotoxicity associated with DOX. To further address DOX resistance, curcumin, serving as a P‐glycoprotein (P‐gp) inhibitor, effectively increased cellular DOX concentration. Consequently, cRGD/PSDOX‐Cur@NPs exhibited synergistic anti‐tumor effects in vitro. Furthermore, in vivo experiments validated the superior BBB penetration and brain‐targeting abilities of cRGD/PSDOX‐Cur@NPs, showcasing the remarkable potential for treating both subcutaneous and orthotopic gliomas. This research underscores that this nanoprodrug delivery system presents a novel approach to inhibiting glioma while addressing resistance and systemic toxicity.