bluuebunny/crossref_metadata_2025_split huggingface dataset:
Penegakan Diagnosis dan Penatalaksanaan Subclavian Steal Syndrome
Authors: Salim Darminto 
Published: February 2025

Abstrak Subclavian steal Syndrome (SSS) merupakan sindrom yang disebabkan penyempitan atauÂ penyumbatanÂ arteri Â subclavia. Penyebab paling sering SSS adalah aterosklerosis. Kelainan ini sering kali tidak terdiagnosis. GejalaÂ umum dari SSS pada lengan atas yang terkena Â klaudikasio, nadi lemah bahkan tidak teraba, perbedaan tekanan darah > 20 mmHg antara kanan dan kiri. Keluhan neurologis (diperburuk dengan latihan lengan) berupa pusing, vertigo, sinkop, ataksia, gangguan penglihatan, disartria, kelemahan, dan, gangguan sensorik. Kelainan neurologis ini disebabkan karena gangguan perfusi serebral. Pemeriksaan penunjang untuk mendiagnosis SSS adalah Â doppler, ultra sonografi, magnetic resonance angiography, dan computed tomography angiography. Terapi untuk SSS: Endovascular, dan operasi bypass. Semua terapi ini bertujuan untuk mengurangi risiko terjadinya penyakit kardiovaskular dan serebrovaskular. Kata kunci: subclavia, perfusi serebral, angiografiÂ Â Abstract Subclavian steal syndrome (SSS) is a syndrome that is caused by abnormal blood flow due to narrowing or blockage of the subclavian artery. The most common cause of SSS is atherosclerosis. The disorder is often not diagnosed. The common symptoms of SSS in the upper arm are claudication, weak pulse does not even exist, differences in blood pressure > 20 mmHg between right and left. Neurological disorder (exacerbated by arm exercises) such as dizziness, vertigo, syncope, ataxia, visual disturbances, dysarthria, weakness, and, sensory disorders. This neurological disorders caused by cerebral perfusion. Investigations to diagnose SSS: doppler, ultra sonography, magnetic resonance angiography, and computed tomography angiography. Therapy for SSS: Endovascular, and bypass surgery. All of this therapy will reduce the risk of cardiovascular and cerebrovascular diseases. Keywords: subclavian, cerebral perfusion, angiography
PENINGKATAN KUALITAS PRODUK DI ERA DIGITAL MELALUI PENDAMPINGAN DAN PELATIHAN PELAKU UMKM DESA KADUARA BARAT
Authors: Firdaus Alfin , Tafrilyanto Chairul Fajar , Zayyadi Moh 
Published: February 2025

Usaha Mikro Kecil dan Menengah (UMKM) merupakan sektor penting dalam perekonomian suatu negara. Dalam era digital abad ke-21, UMKM menghadapi tantangan baru untuk memanfaatkan teknologi digital dalam mengembangkan bisnis mereka.Kegiatan Kuliah Kerja Nyata (KKN) di Desa Kaduara Barat, Kami kelompok KKN 02 Universitas Madura melakukan Pendampinagan sekaligus Pelatihan terhadap masyarakat Desa Kaduara Barat, Kecamatan Larangan, Kabupaten Pamekasan guna memberikan edukasi kepada masyarakat desa khususnya pada Pelaku UMKM di Desa Kaduara barat tentang Peningkatan kualitas Produk, sekaligus kami juga memberikan pendampingan dan pelatihan bagaimana manjemen usaha yaang strategis dengan tujuan pelaku UMKM Desa Kaduara Barat lebih meningkat lagi kualitas produknya. Kegiatan KKN ini dilakukan dengan menggunakan metode pendampingan yaitu dengan melakukan seminar di Balai desa Kaduara Barat. Tujuan dari pelaksanaan pengabdian ini adalah memberikan pengetahuan dan pemahaman tentang bagaimana mengatur dan mengaplikasikan mekanisme usaha yang bagus bagi Pelaku UMKM Adapun target yang diharapkan dalam pengabdian ini adalah meningkatnya Kulaitas Produk pelaku UMKM di Desa Kaduara Barat melalui pelaksanaan seminar oleh kelompok KKN 02 Universitas Madura
To interact or not to interact: The pros and cons of including interactions in linear regression models
Authors: Rimpler Aljoscha , Kiers Henk A.L. , van Ravenzwaaij Don 
Published: February 2025

Abstract
Interaction effects are very common in the psychological literature. However, interaction effects are typically very small and often fail to replicate. In this study, we conducted a simulation comparing the generalizability and estimability of two linear regression models: one correctly specified to account for interaction effects and one misspecified including simple effects only. We manipulated noise levels, predictor variable correlations, and different sets of regression weights, resulting in 9216 different conditions. From each dataset, we drew 1000 samples of N = 25, 50, 100, 250, 500, and 1000, resulting in a total of 55,296,000 analyses for each model. Our results show that misspecification can drastically bias regression estimates, sometimes leading to zero or reversed simple effects. Furthermore, we found that when models are generalized to the entire population, the difference between the explained variance in the sample and in the population is often smaller for the misspecified model than for the correctly specified model. However, the comparison between models shows that the correctly specified model explains the data at the population level better overall. These results emphasize the importance of theory in modeling choices and show that it is important to provide a rationale for why interactions are included or excluded in an analysis.
An Investigation into the Variability of Luminous Blue Variable Stars with TESS
Authors: Spejcher Becca , Richardson Noel D. , Pablo Herbert , Beltran Marina , Butler Payton , Avila Eddie 
Published: February 2025

Abstract
Luminous blue variables (LBVs) are enigmatic, evolved, massive stars. Their variability has been observed to be episodic with large eruptions, along with variations on timescales of days to decades. We have extracted light curves of 37 LBVs from the first 4 yr of the TESS mission. These light curves provide two years of photometric time series for stars in the LMC, with several months of data for Galactic or SMC targets. We analyze the Fourier properties of the stellar light curves to determine their characteristic frequencies and red noise amplitudes, comparing them to mass-loss parameters through Hα strength, and in the case of the LMC stars, B − V color and luminosity as estimated by their apparent g magnitudes. We confirm the absence of correlation between any of the Fourier parameters and stellar parameters, implying that there is no trend in how these stars vary as measured with these photometric data, which may point toward these stars being an extension to the supergiant α Cygni variables and not a unique class of object with regards to their short-term variations.
Spectral Variations across Latitudes on Asteroid (3200) Phaethon
Authors: Angrisani M. , Palomba E. , Longobardo A. , Rognini E. , Migliorini A. , D’Aversa E. , Pratesi G. , Gisellu C. , Dirri F. , Piazzo L. , Arai T. 
Published: February 2025

Abstract
3200 Phaethon is a near-Earth asteroid known to be actively emitting dust and gas when near its perihelion, and it is the target of the Japanese DESTINY+ mission. Several visible–near-IR spectra were obtained of Phaethon during 2003–2017, which have been collected together and analyzed with respect to its shape model. Using a thermal model, we examine the diurnal temperature variations across Phaethon’s surface (ΔT ∼ 600 K). We find different solar radiation heating between the north and south regions, with very high surface temperatures in the south region (max peak ∼ 1050 K), while a lower temperature is found in the north region (a mean value of 760 K). Our analysis of the photometrically corrected slope suggests a latitudinal trend in surface composition. We propose that the northern region of Phaethon may be linked to unusual chondrites and naturally heated Y-82162 samples (63–125 μm and/or chips), while the southern region shows similarities to Ivuna CI chondrites heated to 700°C (0–125 μm). The equatorial region appears to include a mixture of materials from both hemispheres.
ALMA FACTS. II. Large Scale Variations in the 12CO(J = 2 – 1) to 12CO(J = 1 – 0) Line Ratio in Nearby Galaxies
Authors: Komugi Shinya , Sawada Tsuyoshi , Koda Jin , Egusa Fumi , Maeda Fumiya , Hirota Akihiko , Lee Amanda M. 
Published: February 2025

Abstract
We present 12CO(J = 1 – 0) mapping observations over ∼1/2 of the optical disk of 12 nearby galaxies from the Fundamental CO 1–0 Transition Survey of nearby galaxies (FACTS), using the ALMA Total Power array. Variations in the 12CO(J = 2 − 1)/12CO(J = 1 − 0) line ratio r
21 are investigated. The luminosity-weighted r
21 of the 11 sample galaxies ranges from 0.52 to 0.69 with an average of 0.61. We use position–velocity diagrams along the major axis and tilted ring models to separate the normal rotating galactic disk from kinematic outliers that deviate from pure circular rotation. We find that r
21 is systematically higher in outliers compared to the disk. We compare r
21 between SA, SAB, and SB galaxies, and find no significant difference in the average r
21 depending on the presence of galactic bars. We find, however, that the radial gradient in r
21 is bimodal, where a group containing all SA galaxies prefer constant or very shallow r
21 gradients out to 40% of the optical radius, while another group containing all SB galaxies have a steep r
21 gradient, decreasing by ∼20% before 40% of the optical radius, which also corresponds to the radius of the stellar bar. After this radius, these galaxies become consistent with a constant or shallow trend in r
21. The large scale trend in r
21 can have implications for how we interpret observations made solely in the 12CO(J = 2 − 1) line.
PSR J1947−1120: A New Huntsman Millisecond Pulsar Binary
Authors: Strader Jay , Ray Paul S. , Urquhart Ryan , Swihart Samuel J. , Chomiuk Laura , Aydi Elias , Bellm Eric C. , Dage Kristen C. , DeCesar Megan E. , Deneva Julia S. , McLaughlin Maura A. , Molina Isabella , Panurach Teresa , Sokolovsky Kirill V. 
Published: February 2025

Abstract
We present the discovery of PSR J1947–1120, a new huntsman millisecond pulsar with a red giant companion star in a 10.3 day orbit. This pulsar was found via optical, X-ray, and radio follow-up of the previously unassociated γ-ray source 4FGL J1947.6–1121. PSR J1947–1120 is the second confirmed pulsar in the huntsman class and establishes this as a bona fide subclass of millisecond pulsars. We use MESA models to show that huntsman pulsars can be naturally explained as neutron star binaries whose secondaries are currently in the “red bump” region of the red giant branch, temporarily underfilling their Roche lobes and hence halting mass transfer. Huntsman pulsars offer a new view of the formation of typical millisecond pulsars, allowing novel constraints on the efficiency of mass transfer and recycling at an intermediate stage in the process.
Outer Retinal Tubulation and Vision in Geographic Atrophy: A Natural History Analysis From the Phase 3 OAKS and DERBY Trials
Authors: Hatcher Kensington A. , Shah Birva K. , Yu Song , Baumal Caroline R. , Sadda Srinivas 
Published: February 2025

Background and Objective
Outer retinal tubulation (ORT) is an optical coherence tomography finding in numerous chronic retinal diseases, including geographic atrophy (GA). The objective of this study was to evaluate longitudinal best-corrected visual acuity (BCVA) outcomes in patients with GA comparing eyes with and without ORT at baseline.

Patients and Methods
This post hoc longitudinal analysis assessed 300 eyes randomized to sham treatment in the phase 3 OAKS and DERBY trials. Mean change in BCVA over 24 months was calculated, comparing lesions with ORT versus those without ORT at baseline.

Results
Ninety-six (32.0%) of the 300 sham-treated eyes with GA had an ORT at baseline. Eyes with ORT at baseline lost on average 5.5 fewer Early Treatment Diabetic Retinopathy Study letters than eyes without ORT.

Conclusion
Sham-treated eyes with ORT at baseline had less loss of BCVA over 24 months than eyes without ORT.

[
Ophthalmic Surg Lasers Imaging Retina
2025;56:XX–XX.]
Delays in Immediate Athletic Training Evaluation Following Concussion Among High School Football Players: A Report from the Athletic Training Practice-Based Research Network
Authors: Renner Madison N. , Lam Kenneth C. , Stamm Julie M. , Srygler Emily C. , Adler Stephanie N. , Bell David R. 
Published: February 2025

ABSTRACT

Context: Football is the most popular sport among high school boys in the United States. Concussion risk is elevated in the sport due to the high degree of physical contact. Healthcare providers are more likely to be present at the time of concussion during games and for varsity-level athletes, but how time to an immediate athletic trainer (AT) evaluation varies between sport levels and injury settings has yet to be investigated.
Objective: Investigate associations between athlete sport level, injury setting, and same day AT evaluation among high school football players following a concussion. Design: Cross-sectional study.
Setting: Retrospective analysis of de-identified patient records created within the Athletic Training Practice-Based Research Network.
Patients: Patients evaluated and diagnosed with a concussion during in-season high school football participation from 2010-2023. Main outcome measure: Sport level (freshman, junior varsity [JV], varsity), injury setting (game, practice), and same-day evaluation following concussion (yes, no). Results: 1,260 patient cases were included in analysis. A significant association was found between sport level and same-day evaluation (p=0.02), and between injury setting and same-day evaluation (p&lt;.001). A higher percentage of patients playing at the varsity level were evaluated the same day as their injury compared to those playing at the JV and freshman levels. Additionally, a higher percentage of football athletes were evaluated the same day if they sustained an injury during an in-season practice compared to a game. These associations remained significant after stratifying by sport level for freshman (p=0.01) and JV (p&lt;.001) athletes, but not for varsity athletes (p=0.61).
Conclusions: Freshman and JV football athletes, as well as those injured during games, are less likely to receive a same-day evaluation by an AT after concussion. Timely care improves recovery following concussion, emphasizing the need for equitable access to immediate care across sport levels and settings.
Comparison of Long-Term Outcomes in Patients with Supratentorial Spontaneous Intracerebral Hemorrhage Treated with and without Surgical Intervention
Authors: Sharma Agrata , Agarwal Ayush , Garg Ajay , Vishnu Venugopalan Y , Nilima N , Bhatia Rohit , Garg Divyani , Pandit Awadh K , Joseph Leve , Billa Srujana , Singh Manmohan , Suri Ashish , Kale Shashank S , Gaikwad Shailesh B , Srivastava MV Padma 
Published: February 2025

Abstract

Background and Objectives:
Intracerebral hemorrhage (ICH) is associated with high mortality and morbidity. Uncertainty still exists regarding the benefit of surgery in the management of supratentorial spontaneous ICH (sICH), especially of the basal ganglia and thalamus. Studies have not shown the clinical benefit of early surgical management compared to best medical management plus delayed surgery, when necessary. Our aim was to compare the efficacy of different neurosurgical interventions with best medical management and best medical management alone.

Methods:
We conducted a single-center, retrospective study at a tertiary care center in India in sICH patients between January 2015 and December 2022. The primary outcome was functional disability evaluated by the modified Rankin Scale (mRS) at 3, 6, and 12 months. Time-to-event outcomes were compared using the Kaplan–Meier curve.

Results:
Among 2600 stroke patients screened, 661 had sICH. Median age was 55 years, and 250 patients (37.8%) underwent neurosurgical intervention. The most common intervention was craniotomy and hematoma evacuation. The median mRS at discharge and follow-up at 3, 6, and 12 months was lower in the conservatively managed group (4, 3, 3, and 3, respectively) compared to the surgical intervention group (5, 5, 5, 4, respectively). However, the ICH score at admission was lower in the conservatively managed group and after adjustment for ICH score, there was no statistically significant difference between the two. Among the interventions, patients undergoing decompression craniectomy had the best functional outcome.

Conclusions:
Neurosurgical intervention was not associated with better functional outcome when compared to conservative management.
Motor and Non-motor Neurologic Symptoms of Wilson’s Disease: Exploring the Associations
Authors: Chakraborty Arka Prava , Mukherjee Adreesh , Sinharoy Uma , Chakrabarty Madhushree , Sengupta Mainak , Chowdhury Jasodhara , Biswas Atanu 
Published: February 2025

Background and Objectives:
Although the motor symptoms of Wilson’s disease have received particular attention from researchers and medical professionals, non-motor symptoms might become increasingly prevalent with the advancement of the disease and can even appear before the onset of motor symptoms. However, clinicopathological correlations for most of these non-motor features are still poorly understood. The correlations between non-motor and motor symptoms have been examined in this study.

Methods:
Fifty patients with Wilson’s disease participated in this study. Each subject was administered the Global Assessment Scale and the Non-Motor Symptom Questionnaire (NMS Quest) for the assessment of motor and non-motor symptoms, respectively. Cognitive functions were evaluated with Addenbrooke’s Cognitive Examination III (Bengali version) and the Digit Span Test. Sleep-related problems were assessed with Pittsburgh Sleep Quality Index.

Results:
Of the patients who participated in this study, 82%, 56%, 90%, 18%, 82%, 8%, 60%, 56%, and 66% had digestive, urinary, apathy–attention–memory, hallucinations/delusions, depression/anxiety, sexual function, cardiovascular, sleep disorder, and miscellaneous (pain, weight, swelling, sweating, and diplopia) symptoms, respectively. NMS-Digestion (P ≤ 0.001), NMS-Urinary (P = 0.007), NMS-Miscellany (P = 0.001), NMS-Memory (0.011), and NMS-Sleep Disorder (P = 0.031) significantly predicted parkinsonism. NMS-Digestion was a significant predictor of dystonia (P < 0.001).

Conclusion:
Awareness regarding non-motor symptoms and their associations with motor symptoms might help physicians develop more efficient treatment regimens that can alleviate non-motor symptoms which can be equally troublesome and disabling for these patients. Management of non-motor symptoms is crucial for the overall well-being of these patients.
Aberrant CD3 positive plasmablastic lymphoma of small bowel in a HIV negative, EBV negative patient: A case report
Authors: Idrees Umama , Das Mayurakshi , Sekaran Anuradha , Reddy Duvvur N. 
Published: February 2025

ABSTRACT
Plasmablastic lymphoma (PBL) is an aggressive lymphoma with the proliferation of plasmablastic cells with a plasma cell immunophenotype and immunonegativity for B-cell markers. Here we present a case of jejunal PBL in an 82-year-old human immunodeficiency virus (HIV) negative and Epstein-Barr (EBV) negative male who presented with subacute intestinal obstruction and histopathological examination showed a large cell lymphoma with plasmablastic differentiation diffusely infiltrating full thickness of the jejunal wall. Neoplastic cells were immunopositive for CD138, MUM-1, EMA, and CD56, along with aberrant expression of pan T-cell marker CD3. No restrictions for kappa and lambda light chains were noted. Ki67 index was >90%. Tumor cells were immunonegative for CD20, CD5, CD7, CD30, and PAX 5. Suspicion of this rare and high-grade lymphoma in immunocompetent patients and at extra-nodal locations along with awareness of diagnostic pitfalls in its immunoprofile will aid in accurate diagnosis and prognostication.
The Use of Intrathecal Dexmedetomidine and Fentanyl as Adjuvants to Bupivacaine – A Cross-sectional Analytical Study
Authors: Mammen Annie , Ravi K. R. , Joseph Aubry 
Published: February 2025

Abstract

Introduction:
In spinal anesthesia, dexmedetomidine and fentanyl are frequently added as adjuncts to local anesthetics to extend analgesia and enhance postoperative pain management. The purpose of this prospective observational study was to evaluate the effectiveness of intrathecal fentanyl and dexmedetomidine as adjuvants to bupivacaine for the management of postoperative pain in patients having lower abdominal operations.

Methods:
Eligible patients who received intrathecal anesthetic with bupivacaine plus either fentanyl (Group F) or dexmedetomidine (Group D) were studied. Age, gender distribution, the American Society of Anesthesiologists classification, and length of operation were recorded as baseline variables. The longest length of the sensory block, the highest sensory level attained, the time it took to reach the maximum sensory level, and the results of the postoperative pain were measured as aspects of the sensory block.

Results:
Comparable levels of sensory block were attained by the dexmedetomidine and fentanyl groups. There was no significant difference in the maximum sensory level attained (P = 0.89) or in the time from injection to the greatest sensory level (P = 0.57). Nevertheless, as demonstrated by a longer time for two-segment regression from the maximum sensory level (P < 0.001) and a delayed time to sensory regression to S1 (P < 0.001), dexmedetomidine demonstrated a considerably longer duration of sensory block compared to fentanyl. In addition, compared to fentanyl, dexmedetomidine was linked to a lower total analgesic dose in the first 24 h postoperatively (P = 0.03) and a noticeably longer duration to rescue analgesia (P < 0.001).

Discussion:
Our study suggest that intrathecal dexmedetomidine provides prolonged sensory block duration and reduced postoperative analgesic requirements compared to fentanyl when used as an adjuvant to bupivacaine for intrathecal anesthesia. These results have significant implications for improved pain management and enhanced patient outcomes in various surgical procedures.
Autologous Dura For Dural Defect Repair: A Technical Note
Authors: Rai Survendra Kumar R , Dandpat Saswat K , Jadhav Dikpal , Bhambere Sagar , Bhatia Kushal , Gajbhiye Nikhil K , Goel Atul H 
Published: February 2025

Background:
Quest for finding ideal graft material for covering dural defect continues. Dura mater (DM)/pachymeninges consists of two layers; hence possibility of splitting this layer has been explored.

Objective:
Microsurgical splitting of dura into two layers for covering the dural defect.

Materials and Methods:
Splitting of DM with number 15 surgical blade was carried out on ten cadavers. Splitting the dura into two distinct layers was possible in every specimen paving way for implementing in routine neurosurgical practice. This technique was implemented in covering accidental dural defects in seven cases with defects ranging from 1 cm to 3.5 cm. All cases were followed up for potential complications in the long run.

Results:
Harvesting autologous dural graft by splitting it into two layers was possible with number 15 scalpel in autopsy specimen and routine neurosurgical practice. All dural defects were repaired without any complication with follow-up of more than 1 year.

Conclusions:
Best replacement of dural defect is by dura itself. The technique of harvesting autologous dura by splitting into two layers is easy, inexpensive, and devoid of all graft-related complications found till date. Splitting of dura is technically demanding but possible in small- to medium-sized dural defects. This technique has inherent limitations arising due to the amount of surrounding dura available depending on the size of craniotomy and the size of the dural defect. This procedure cannot become a substitute for cases requiring the extensive sacrifice of the dura, especially during meningioma surgery. This technique emphasis value of good microsurgical techniques.