bluuebunny/crossref_metadata_2025_split huggingface dataset:
Ideas and Innovations: Complete Resolution of Surgical Marking Tattoo Postminimal Access Cranial Suspension Facelift Using a High-power Picosecond Laser
Authors: Nemcevic Andjela , Bajaj Shirin , Geronemus Roy 
Published: March 2024

Summary:
Traumatic tattoos can occur when foreign pigment particles are embedded within the dermis, sometimes resulting as traumatic events. Traditional treatment modalities, including surgical excision, cryosurgery, electrosurgery, dermabrasion, CO2 lasers, and argon lasers, have limitations such as nonselectivity for pigment and risks of scarring and discoloration. We present the case of a patient who developed a postoperative tattoo after a minimal access cranial suspension facelift procedure that subsequently completely resolved after treatment with the high-powered 1064-nm picosecond laser. The patient achieved complete resolution of the postoperative tattoo after five laser treatments without adverse events or recurrence of pigmentation on follow-up. High-powered 1064-nm picosecond laser can serve as a fast, safe, and effective modality that in our clinic has become the first-line treatment for traumatic tattoos, and in our patient led to high satisfaction.
Jawline Aesthetic Definition: Enhancement with Masseteric Augmentation Using Ultrasound-Guided Fat Transfer
Authors: Manzaneda Cipriani Raul M. , Cárdenas Larenas Juan Pablo , Viaro Mauricio S.S. , Flores González Emmanuel A. , Adrianzen Gerardo , Babaitis Ricardo , Duran Vega Héctor , Stefanelli Matt , Ventura Ricardo 
Published: March 2024

Background:
The rejuvenation and restoration of a well-defined jawline contour are crucial for enhancing facial aesthetics in both men and women. Within the jawline aesthetic unit (mandibular angle), the masseter muscle plays a significant role, as it is responsible for mandibular masticatory movements. We propose a new approach using ultrasound-guided intramuscular fat transfer to enhance the mandibular angle and jawline.

Methods:
The multicenter study included 20 patients from three countries (Peru, Brazil, and Mexico). After fat harvesting, the ultrasound-guided masseteric fat transfer was performed with a 1.5-mm Viaro cannula from an incision beneath the ear lobule. The fat was then injected intramuscularly into the masseter at each side of the mandibular angle.

Results:
Masseter ultrasound-guided fat transfer was performed on 10 men and 10 women between 2021 and 2022. The patients had a mean age of 34.4 ± 6.39 years and a mean body mass index of 22.39 ± 2.59 kg per m2. The mean injected volume was 5.83 mL and 5.58 mL on the right and left sides, respectively. Muscle thickness increased in patients immediately postsurgery, but decreased after 1 month. The muscle remained significantly thicker on each side than the presurgery measurements in patients regardless of gender (both P < 0.0001).

Conclusions:
Ultrasound-guided intramuscular fat transfer is a safe and reproducible technique for enhancing the jawline contour at the mandibular angle. We believe that it could be a more durable solution than other procedures, although further evaluation of long-term results is necessary.
Capture, Coding, and Reporting of Health Care and Medicine Information in Australian Workers’ Compensation Systems
Authors: Tefera Yonas Getaye , Di Donato Michael , Sheehan Luke R. , Gray Shannon , Nielsen Suzanne , Xia Ting , Collie Alex 
Published: March 2024

Objective
This study aims to characterize the approaches to collecting, coding, and reporting health care and medicines data within Australian workers’ compensation schemes.

Methods
We conducted a cross-sectional survey of data and information professionals in major Australian workers’ compensation jurisdictions. Questionnaires were developed with input from key informants and a review of existing documentation.

Results
Twenty-five participants representing regulators (40%) and insurers (60%) with representation from all Australian jurisdictions were included. Health care and medicines data sources, depth, coding standards, and reporting practices exhibited significant variability across the Australian workers’ compensation schemes.

Conclusions
Substantial variability exists in the capture, coding, and reporting of health care and medicine data in Australian workers’ compensation jurisdictions. There are opportunities to advance understanding of medicines and health service delivery in these schemes through greater harmonization of data collection, data coding, and reporting.
Could nerve transplantation be the future of this field: a bibliometric analysis about lumbosacral plexus injury
Authors: Wang Sheng , Xia Demeng , Song Danyan , Lu Nan , Chen Aimin 
Published: March 2024

Background:
Lumbosacral plexus injury is a highly distressing clinical issue with profound implications for patients’ quality of life. Since the publication of the first relevant study in 1953, there has been very limited progress in basic research and clinical treatment in this field, and the developmental trajectory and research priorities in this field have not been systematically summarized using scientific methods, leaving the future direction of this research to be explored.

Methods:
Utilizing publications from the Web of Science (WoS) database, our research employed bibliometric methodology to analyze the fundamental components of publications, synthesize research trends, and forecast future directions.

Results:
A total of 150 publications were included in our study, and the impressive advancement of research heat in this field can be attributed to the continuous increase in the number of papers, ranging from 14 papers in 2000 to 34 papers in 2023 over 5 years. Regarding the country, a central position in both quantity (H-index=125) and quality of publications (65 publications) is occupied by the United States, and close collaborations with other countries are observed. In terms of publication institutions, the highest number of publications (nine publications) is held by the Second Military Medical University. The journal with the most publications (five publications) is the Journal of Trauma-Injury Infection and Critical Care. A pivotal role has been played by basic medical research in the development of this field. Concerning hotspots, the focus of the research core can be divided into three clusters (etiology, diagnosis and treatment; molecular, cells and mechanisms; physiology, and pathology).

Conclusion:
This marks the inaugural bibliometric analysis of lumbosacral plexus injuries, offering a comprehensive overview of current publications. Our findings illuminate future research directions, international collaborations, and interdisciplinary relationships. Future research will emphasize clinical treatment and mechanism research, with a focus on sacral nerve stimulation and nerve transplantation.
Is the Position of the Basal-Most Electrode Depending on Electrode Array Design and Influencing Postoperative Speech Perception? A Retrospective Analysis of 495 Ears
Authors: Beck Rainer Linus , Aschendorff Antje , Arndt Susan , Hildenbrand Tanja , Ketterer Manuel Christoph 
Published: March 2024

Objective
The objective of this study is to examine the influence of electrode array design on the position of the basal-most electrode in cochlear implant (CI) surgery and therefore the stimulability of the basal cochlea. Specifically, we evaluated the angular insertion depth of the basal-most electrode in perimodiolar and straight electrode arrays in relation to postoperative speech perception.

Materials and Methods
We conducted a retrospective analysis of 495 patients between 2013 and 2018 using the Cochlear™ Contour Advance® (CA), Cochlear™ Slim Straight® (SSA), or Cochlear™ Slim Modiolar® (SMA) electrode arrays, as well as the MED-EL Flex24 (F24), MED-EL Flex28 (F28), and MED-EL FlexSoft (F31.5) electrode arrays. Cochlear size and the position of the basal-most electrode were measured using rotational tomography or cone beam computed tomography, and the results were compared with postoperative speech perception in monosyllables and numbers.

Results
The straight electrode arrays, specifically the F31.5 (31.5 mm length) and the F28 (28 mm length), exhibited a significantly greater angular insertion depth of the basal-most electrode. No significant correlation was found between cochlear morphology measurements and the position of the basal-most electrode artifact. Cochleostomy-inserted electrode arrays showed a significantly higher insertion depth of the basal-most electrode. Nevertheless, the position of the basal-most electrode did not have a significant impact on postoperative speech perception.

Conclusion
Straight electrode arrays with longer lengths achieved deeper angular insertion depths of the basal-most electrode. Cochlear morphology does not have a substantial influence on the position of basal-most electrode. The study confirms that the basal area of the cochlea, responsible for high-frequency range during acoustic stimulation, is not the primary region for speech understanding via electrical stimulation with CI.
Concordance Analysis of the Pressure Chamber and Tubomanometer According to Estève for the Determination of Eustachian Tube Opening Pressure
Authors: Deuss Eric , Löding Katharina , Breitrück Nils , Lang Stephan , Klußmann Jens Peter , Jansen Stefanie , Meyer Moritz Friedo 
Published: March 2024

Introduction
For the diagnosis of Eustachian tube dysfunction (ETD), clinical procedures such as tympanometry, micro-otoscopy, and maneuvers according to Toynbee and Valsalva only allow an indirect assessment for the moment. With a prevalence of up to 5%, the selection of patients with ETD and its subtypes is clinically relevant. Dynamic methods of Eustachian tube function assessment include a hypo/hyperbaric pressure chamber and Estève’s tubomanometer (TMM). One method of assessing ETD is the evaluation of Eustachian tube opening pressure (ETOP).

Material and Methods
We performed a concordance analysis between pressure chamber and TMM to determine ETOP. For this purpose, we analyzed the measurements of both methods from 28 healthy subjects using Bland–Altman plots, regression according to Passing–Bablok and Lin’s concordance correlations coefficient. The maximum tolerated clinical deviation of measured values was set at 10%.

Results
A maximum of 53 measurements of ETOP between pressure chamber and TMM were compared. Mean ETOP for TMM was 28.7 hPa, passive opening was 32 hPa, Toynbee maneuver was 28.4 hPa, and Valsalva maneuver was 54.6 hPa. Concordance analysis revealed following results: passive opening versus TMM: Bland–Altman mean difference 3.3 hPa, limits of agreement ±31.8 hPa; Passing–Bablok regression y = 0.67x + 9.36; Lin’s r
ccc = 0.18. Toynbee versus TMM: Bland–Altman mean difference 0.7 hPa, limits of agreement ±35.8 hPa; Passing–Bablok regression y = 0.47x + 14.03; Lin’s r
ccc = 0.14. Valsalva versus TMM: Bland–Altman mean difference 24.2 hPa, limits of agreement ±117.5 hPa; Passing–Bablok regression y = 0.17x + 25.12; Lin’s r
ccc = 0.18.

Conclusion
Estève‘s tubomanometer and pressure chamber measurements of ETOP are not concordant. The two methods cannot be interchanged without reservation.
Gut hormones and appetite regulation
Authors: Hong So-hyeon , Choi Kyung Mook 
Published: March 2024

Purpose of review
Various gut hormones interact with the brain through delicate communication, thereby influencing appetite and subsequent changes in body weight. This review summarizes the effects of gut hormones on appetite, with a focus on recent research.

Recent findings
Ghrelin is known as an orexigenic hormone, whereas glucagon-like peptide-1 (GLP-1), glucose-dependent insulinotropic polypeptide (GIP), cholecystokinin (CCK), postprandial peptide YY (PYY), and oxyntomodulin (OXM) are known as anorexigenic hormones. Recent human studies have revealed that gut hormones act differently in various systems, including adipose tissue, beyond appetite and energy intake, and even involve in high-order thinking. Environmental factors including meal schedule, food contents and quality, type of exercise, and sleep deprivation also play a role in the influence of gut hormone on appetite, weight change, and obesity. Recently published studies have shown that retatrutide, a triple-agonist of GLP-1, GIP, and glucagon receptor, and orforglipron, a GLP-1 receptor partial agonist, are effective in weight loss and improving various metabolic parameters associated with obesity.

Summary
Various gut hormones influence appetite, and several drugs targeting these receptors have been reported to exert positive effects on weight loss in humans. Given that diverse dietary and environmental factors affect the actions of gut hormones and appetite, there is a need for integrated and largescale long-term studies in this field.
Handgrip Strength Predicts Survival in Patients With Pancreatic Cancer
Authors: Freckelton Julia , Rajagopalan Ashray , Moore Gregory T. , Croagh Daniel 
Published: March 2024

Objectives
Pancreatic ductal adenocarcinoma (PDAC) is a common cancer with a poor prognosis and is associated with a high prevalence of cachexia, a metabolic syndrome of muscle wasting due to complex mechanisms. In addition to loss of muscle mass, cancer patients also experience functional deterioration. The aim of this study is to determine whether there is an association between muscle mass and function and clinical outcomes, particularly survival.

Methods
We performed a prospective cohort study including all patients with PDAC at Monash Health from March 2016 to December 2017. We conducted body composition analysis for myopenia and handgrip strength testing. We constructed Kaplan-Meier curves to estimate whether myopenia and low hand grip strength were associated with poorer survival.

Results
Myopenia was not associated with a significant difference in PDAC-specific survival (log-rank P = 0.60). However, low handgrip strength was associated with significantly worse PDAC-specific survival compared with other patients (log-rank hazard ratio, 1.88; 95% confidence interval, 1.15–3.09; P = 0.004).

Conclusions
The relationship between survival in PDAC and handgrip strength, but not anatomical muscle mass, suggests that functional testing of strength may be important in prognostication of patients with PDAC, alongside existing tools such as the Eastern Cooperative Oncology Group performance status.
Individualized prediction of conditional survival for colorectal signet-ring cell carcinoma patients
Authors: Gu Jiani , Zhang Lijun , Zhang Yanjin , Chen Xia , Gu Ting , Cai Jidong , Yao Lifeng , Yan Lihua 
Published: March 2024

Background:
Conditional survival (CS) considers the time already survived after surgery and may provide additional survival information. The authors sought to construct and validate novel conditional survival nomograms for the prediction of conditional overall survival (OS) and cancer-specific survival (CSS) of colorectal signet-ring cell carcinoma (SRCC) patients.

Methods:
Patients diagnosed with stage I–III SRCC between 2010 and 2019 were identified from the Surveillance, Epidemiology, and End Results database. The formula calculating CS was: CS(x|y) = S(x+y)/S(x), where S(x) represents the survival at x years. CS nomograms were then constructed to predict the 5-year conditional OS and CSS, followed by internal validation.

Results:
A total of 944 colorectal SRCC patients were finally identified in this study. The 5-year OS and CSS improved gradually with additional survival time. Univariate and multivariate Cox regression analysis conducted in training set revealed that age, race, T stage, LNR, and perineural invasion were independent risk factors for both OS and CSS. Two nomograms with considerable predictive ability were successfully constructed [area under the curve (AUC) for OS: 0.788; AUC for CSS: 0.847] and validated (AUC for OS: 0.773; AUC for CSS: 0.799) for the prediction of 5-year OS and CSS, based on the duration of 1–4 years post-surgery survival.

Conclusions:
The probability of achieving 5-year OS and 5-year CSS in colorectal SRCC patients improved gradually with additional time. Conditional nomograms considering survival time will be more reliable and informative for risk stratification and postoperative follow-up.
Toward subtalar joint axis–driven computer-aided design and computer-aided manufacturing foot orthoses: Reliability of a noninvasive clinical scanning protocol
Authors: Potier Clément , Claeys Kurt , Deschamps Kevin 
Published: March 2024

Background:
The subtalar joint axis (STJA) occupies a key role in the dynamics of the lower limb kinetic chain, and its location has a wide interindividual variability. It has been suggested that considering the STJA location when designing foot orthoses may help to apply the required mechanical dose. However, the evidence is more anecdotal than empirical.

Objective:
This study aimed to evaluate the reliability of the STJA digitization, a procedure combining the clinical determination of the functional STJA location and its subsequent 3-dimensional (3D) scanning.

Study Design:
Two examiners identified the posterior and anterior exit points of the functional STJA on the skin of 15 healthy participants using a clinical method in a repeated-measure design.

Methods:
A handheld 3D scanner was used to scan the feet and the skin markers. The 3D coordinates of the skin markers were subsequently quantified and (1) STJA digitization intratester within-session, (2) STJA digitization intratester between-session, and (3) STJA digitization intertester between-session reliabilities were evaluated.

Results:
When pooling all skin marker 3D coordinates, intraclass correlation coefficients (ICCs) for the STJA intratester within-session reliability ranged from 0.74 to 0.98. ICCs for the STJA digitization intratester between-session reliability ranged from 0.58 to 0.94. ICCs for the STJA digitization intertester reliability ranged from 0.56 to 0.81. Standard error of measurement for the mediolateral position of the talus marker (anterior exit point of the STJA) was substantially higher than that for the other coordinates.

Conclusions:
Overall, the STJA digitization demonstrated a good intratester between-session reliability and may be used in a computer-aided design and computer-aided manufacturing workflow to create foot orthoses. However, further efforts should be considered to improve the scanning process and intertester reliability.
Factors Associated With Onabotulinum Toxin-A Discontinuation in a Diverse Urban Population
Authors: Bergeron Tyler , Harandi Arshia Aalami , Liebeskind Mariel , Abraham Nitya 
Published: March 2024

Importance
Although overactive bladder (OAB) is a common condition, affecting 16% of Americans, few patients continue on to advanced therapies. Furthermore, procedural therapies like intravesical onabotulinum toxin-A (BTX-A), which require ongoing repeat treatments, have discontinuation rates ranging from 25% to 51%.

Objectives
This study sought to investigate factors associated with dis-continuation of BTX-A injections for idiopathic OAB among a diverse urban population.

Study Design
This was a retrospective review of adults 18 years and older who underwent BTX-A injection for idiopathic OAB. Patient demographics, past medical history, symptoms, and postprocedural outcomes such as subjective improvement, urinary retention, and incidence of urinary tract infection were compared between groups.

Results
Onabotulinum toxin-A injections were administered to 246 patients who met study criteria, of whom 211 (85.7%) were women. One hundred (40.7%) patients discontinued BTX-A therapy. Patients discontinuing BTX-A therapy were more likely to have developed postprocedural urinary retention (18.4% vs 9.7%, P < 0.05) and had a higher median income by zip code ($59,000 vs $50,000; P < 0.01). Patients were significantly more likely to continue BTX-A therapy if they reported preprocedural nocturia (57.2% vs 36.8%, P < 0.01) or urgency urinary incontinence (UUI) (78.1% vs 64.6%, P < 0.05).

Conclusions
Adverse outcomes, such as postprocedural urinary retention, are associated with discontinuation of BTX-A therapy. Patients who reported nocturia and UUI before injection were more likely to continue BTX-A suggesting more severe OAB is more responsive to this therapy. Given the large proportion (>40%) of patients who discontinued BTX-A treatment, further research is needed to identify barriers to continuation of care.
Exploring the role of cultivar, year and plot age in the incidence of esca and Eutypa dieback: insights from 20 years of regional surveys in France
Authors: Etienne Lucas , Fabre Frédéric , Martinetti Davide , Frank Elise , Michel Lucie , Bonnardot Valérie , Guérin-Dubrana Lucia , Delmas Chloé E. L. 
Published: March 2024

AbstractGrapevine trunk diseases cause yield losses and vine mortality in vineyards worldwide. However, there have been few quantitative studies evaluating grapevine dieback on a large spatial and temporal scale. Here, we consolidated and standardized databases from the 13 main wine regions of France, compiling records of leaf symptoms associated with esca and Eutypa dieback from 2082 plots and 36 cultivars over a 20-year period. This large dataset was used (a) for quantitative analysis of the prevalence (number of plots with at least one symptomatic plant) and incidence (percentage of symptomatic plants) of esca and Eutypa dieback; and (b) to decipher the effects of cultivar, year and plot age on both the prevalence and incidence of esca leaf symptoms by temporal Bayesian modelling. Esca was present on a mean of 74 ± 2% plots annually, with an incidence of 3.1 ± 0.1%. Eutypa dieback occurred in 41 ± 3% of the plots, with an incidence of 1.4 ± 0.1%. Our modelling approach revealed that the cultivar had a significant impact on the prevalence of esca, but not on its incidence when prevalence is greater than zero. Esca prevalence remained stable, whereas esca incidence was higher than the mean value in six of the years after 2012. We also found a significant non-linear effect of plot age, with 10- to 30-year-old plots significantly more susceptible, depending on the cultivar. This study clearly illustrates the importance of considering extensive and continuous monitoring to improve our understanding of the impact and evolution of crop diseases.