bluuebunny/crossref_metadata_2025_split huggingface dataset:
Synthesis of Bi‐ and Tricyclic Arylboronates via Cp*RuCl‐Catalyzed Cycloaddition of α,ω‐Diynes with Ethynylboronate.
Authors: Yamamoto Yoshihiko , Hattori Kozo , Ishii Jun‐ichi , Nishiyama Hisao , Itoh Kenji 
Published: December 2005

AbstractFor Abstract see ChemInform Abstract in Full Text.
Domino Reactions with Fluorinated Five‐Membered Heterocycles — Syntheses of Trifluoromethyl Substituted Butenolides and γ‐Ketoacids.
Authors: Burger Klaus , Hennig Lothar , Fuchs Annett , Greif Dieter , Spengler Jan , Albericio Fernando 
Published: December 2005

AbstractFor Abstract see ChemInform Abstract in Full Text.
Versatile Hypervalent Iodine(III)‐Catalyzed Oxidations with m‐Chloroperbenzoic Acid as a Cooxidant.
Authors: Dohi Toshifumi , Maruyama Akinobu , Yoshimura Misaki , Morimoto Koji , Tohma Hirofumi , Kita Yasuyuki 
Published: December 2005

AbstractFor Abstract see ChemInform Abstract in Full Text.
8‐Methylquinoline Palladacycles: Stable and Efficient Catalysts for Carbon—Carbon Bond Formation.
Authors: Evans Paul , Hogg Paul , Grigg Ronald , Nurnabi Mohamed , Hinsley Joanne , Sridharan Visuvanathar , Suganthan Selvaratnam , Korn Stewart , Collard Simon , Muir Jane E. 
Published: December 2005

AbstractFor Abstract see ChemInform Abstract in Full Text.
Efficient Method for the Direct Preparation of Amides from Carboxylic Acids Using Tosyl Chloride under Solvent‐Free Conditions.
Authors: Khalafi‐Nezhad Ali , Parhami Abolfath , Rad Mohammad Navid Soltani , Zarea Abdolkarim 
Published: December 2005

AbstractFor Abstract see ChemInform Abstract in Full Text.
Stereoselective Transformation of Easily Available (2Z,4E)‐2,4‐Alkadien‐1‐ols into (E)‐3‐Alkene‐1,2,5‐triol Derivatives.
Authors: Yoshida Shinya , Asano Moriteru , Kobayashi Yuichi 
Published: December 2005

AbstractFor Abstract see ChemInform Abstract in Full Text.
Diastereoselective SmI2‐Mediated 3‐exo‐trig Cyclization of δ‐Oxo‐Alkylidenemalonates to Cyclopropanols.
Authors: Zriba Riadh , Bezzenine‐Lafollee Sophie , Guibe Francois , Guillerez Marie‐George 
Published: December 2005

AbstractFor Abstract see ChemInform Abstract in Full Text.
Asymmetric Synthesis by the Intramolecular Haloetherification Reaction of Ene Acetal: Discrimination of Prochiral Dienes in Cyclohexane Systems.
Authors: Fujioka Hiromichi , Kotoku Naoyuki , Sawama Yoshinari , Kitagawa Hidetoshi , Ohba Yusuke , Wang Tsung‐Lung , Nagatomi Yasushi , Kita Yasuyuki 
Published: December 2005

AbstractFor Abstract see ChemInform Abstract in Full Text.
Pd/C‐Mediated Coupling of Aryl Halides with Terminal Alkynes in Water.
Authors: Batchu Venkateswara Rao , Subramanian Venkataraman , Parasuraman Karuppasamy , Swamy Nalivela Kumara , Kumar Sanjeev , Pal Manojit 
Published: December 2005

AbstractFor Abstract see ChemInform Abstract in Full Text.
Reductive Sulfur Extrusion Reaction of 2,1,3‐Benzothiadiazole Compounds: A New Methodology Using NaBH4/CoCl2×6H2O(cat) as the Reducing System.
Authors: DaSilveira Neto Brenno A. , Lopes Aline S. , Wuest Martina , Costa Valentim E. U. , Ebeling Guenter , Dupont Jairton 
Published: December 2005

AbstractFor Abstract see ChemInform Abstract in Full Text.
Reversal of Aryl Bromide Reactivity in Pd‐Catalyzed Aryl Amination Reactions Promoted by a Hemilabile Aminophosphine Ligand.
Authors: Parisel Sebastien L. , Adrio Luis Angel , Pereira Adriana Amoedo , Perez Marta Marino , Vila Jose M. , Hii King Kuok 
Published: December 2005

AbstractFor Abstract see ChemInform Abstract in Full Text.
Discovery of Chiral Catalysts by Asymmetric Activation for Highly Enantioselective Diethylzinc Addition to Imines: Using Racemic and Achiral Diimines as Effective Activators.
Authors: Liu Hua , Zhang Hai‐Le , Wang Shuang‐Jun , Mi Ai‐Qiao , Jiang Yao‐Zhong , Gong Liu‐Zhu 
Published: December 2005

AbstractFor Abstract see ChemInform Abstract in Full Text.
Effect of Sodium Naphthalenide, a Key SET Reagent, on Trifluoroacetyl Derivatives.
Authors: Banerji Avijit , Bandyopadhyay Debasish , Basak Bidyut , Sur Kumar R. , Paul Jyoti N. , Banerji Julie , Chatterjee Asima 
Published: December 2005

AbstractFor Abstract see ChemInform Abstract in Full Text.
One‐Pot Synthesis of Trisubstituted Monomethylated Benzene‐1,3‐diols via a Michael Addition—Dieckmann Cyclization Sequence from Methyl (E)‐3‐Methoxy‐4‐methoxycarbonylbut‐2‐enoate Anion and Methyl Alkynoates and Its Application to the Total Synthesis of Nidulol.
Authors: Covarrubias‐Zuniga Adrian , San German‐Sanchez Laura , Maldonado Luis A. , Romero‐Ortega Moises , Avila‐Zarraga Jose G. 
Published: December 2005

AbstractFor Abstract see ChemInform Abstract in Full Text.
N,N′‐Diiodo‐N,N′‐1,2‐ethanediylbis(p‐toluenesulfonamide) as a Reagent for Conversion of Aldehydes to Methyl Esters.
Authors: Ghorbani‐Vaghei Ramin , Shahbazee Elham , Veisi Hojat 
Published: December 2005

AbstractFor Abstract see ChemInform Abstract in Full Text.
Unusual Transformations of N‐[2,2,2‐Trichloro‐1‐(4‐methylphenyl)ethyl]‐4‐chlorobenzenesulfonamide by the Action of Dipropylamine
Authors: Rozentsveig I. B. , Levkovskaya G. G. , Albanov A. I. , Dmitrieva I. L. , Mirskova A. N. 
Published: December 2005

AbstractFor Abstract see ChemInform Abstract in Full Text.
Catalytic Activity of η2‐(Olefin)palladium(0) Complexes with Iminophosphine Ligands in the Suzuki—Miyaura Reaction. Role of the Olefin in the Catalyst Stabilization.
Authors: Scrivanti Alberto , Beghetto Valentina , Matteoli Ugo , Antonaroli Simonetta , Marini Alessia , Crociani Bruno 
Published: December 2005

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Palladium—Benzimidazolium Salt Catalyst Systems for Suzuki Coupling: Development of a Practical and Highly Active Palladium Catalyst System for Coupling of Aromatic Halides with Arylboronic Acids.
Authors: Huang Wen , Guo Jianping , Xiao Yuanjing , Zhu Miaofen , Zou Gang , Tang Jie 
Published: December 2005

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Pd2(dba)3/P (i‐BuNCH2CH2)3N: A Highly Efficient Catalyst for the One‐Pot Synthesis of trans‐4‐N,N‐Diarylaminostilbenes and N,N‐Diarylaminostyrenes.
Authors: Nandakumar Mecheril V. , Verkade John G. 
Published: December 2005

AbstractFor Abstract see ChemInform Abstract in Full Text.
Convenient and Efficient Synthesis of 1,1‐Bis‐(4‐alkylthiophenyl)‐1‐alkenes via Tandem Friedel—Crafts Acylation and Alkylation of Sulfides and Acyl Chlorides.
Authors: Xu Jiaxi , Xia Jiakun , Lan Yu 
Published: December 2005

AbstractFor Abstract see ChemInform Abstract in Full Text.
Photo‐Induced Aromatic Assembly of Benzocycloalka[1,2‐b]furan and Spiro[furan‐2(3H),1′‐benzocycloalkane] Derivatives.
Authors: Fujino Reika , Kajikawa Shougo , Nishino Hiroshi 
Published: December 2005

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Efficient and Scalable Arylation of Bicyclic Lactones to Form Quaternary Centers Using Conventional and Microwave Radiation.
Authors: Malcolm Scott C. , Ribe Seth , Wang Fengjiang , Hewitt Michael C. , Bhongle Nandkumar , Bakale Roger P. , Shao Liming 
Published: December 2005

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Synthesis of 2‐Azetidinones from 2‐Diazo‐1,2‐diarylethanones and N‐(2‐Thienylidene)imines as Possible Antimicrobial Agents.
Authors: Singh Girija S. , Mmolotsi Boycie J. 
Published: December 2005

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Efficient Fluoride‐Mediated Synthesis of 5‐Alkyl Amino‐ and Ether‐Substituted Pyrazoles
Authors: Shavnya Andrei , Sakya Subas M. , Minich Martha L. , Rast Bryson , DeMello Kristin Lundy , Jaynes Burton H. 
Published: December 2005

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Antibacterial 4‐Amino‐N‐(5‐methylisoxazol‐3‐yl)‐N‐ [(4‐oxo‐2‐phenyl‐4H‐1‐benzopyran‐6‐yl)methyl]benzenesulfonamide.
Authors: Oezbey Sueheyla , Akbas Arzu , Ayhan‐Kilcigil Guelguen , Ertan Rahmiye 
Published: December 2005

AbstractFor Abstract see ChemInform Abstract in Full Text.
Phase Transfer Catalyzed Synthesis under Ultrasonic Irradiation and Bioactivity of N′‐(4,6‐Disubstituted‐pyrimidin‐2‐yl)‐N‐(5‐aryl‐2‐furoyl)thiourea Derivatives.
Authors: Ke Shao‐Yong , Wei Tai‐Bao , Xue Si‐Jia , Duan Li‐Ping , Li Jing‐Zhi 
Published: December 2005

AbstractFor Abstract see ChemInform Abstract in Full Text.
(E)‐8‐(3‐Chlorostyryl)‐1,3‐7‐trimethylxanthine, a Caffeine Derivative Acting Both as Antagonist of Adenosine A2A Receptors and as Inhibitor of MAO‐B.
Authors: Frederick Raphael , Ooms Frederic , Castagnoli Neal Jr. , Petzer Jacques P. , Feng Jiang‐Fan , Schwarzschild Michael A. , Van der Schyf Cornelis J. , Wouters Johan 
Published: December 2005

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The Isolation and Structure Elucidation of a New Sesquiterpene Lactone from the Poisonous Plant Coriaria japonica (Coriariaceae).
Authors: Kinoshita Takeshi , Itaki Nao , Hikita Maho , Aoyagi Yutaka , Hitotsuyanagi Yukio , Takeya Koichi 
Published: December 2005

AbstractFor Abstract see ChemInform Abstract in Full Text.
Microbial Transformation of Mestranol by Cunninghamella elegans.
Authors: Choudhary Muhammad Iqbal , Musharraf Syed Ghulam , Siddiqui Zafar Ali , Khan Naik Tameen , Ali Rahat Azhar , Atta‐ur‐Rahman Atta‐ur‐Rahman 
Published: December 2005

AbstractFor Abstract see ChemInform Abstract in Full Text.
Evaluation of Strychnos pseudoquina St. Hil. Leaves Extract on Gastrointestinal Activity in Mice.
Authors: Aparecido da Silva Marcelo , Murino Rafacho Bruna Pola , Hiruma‐Lima Clelia Akiko , Machado da Rocha Lucia Regina , Campaner dos Santos Lourdes , Sannomiya Miriam , Monteiro Souza‐Brito Alba Regina , Vilegas Wagner 
Published: December 2005

AbstractFor Abstract see ChemInform Abstract in Full Text.
First Total Synthesis of the Biologically Active 2,7‐Dioxygenated Tricyclic Carbazole Alkaloids 7‐Methoxy‐O‐methylmukonal (IIIa), Clausine H (Clauszoline‐C) (IIIb), Clausine K (Clauszoline‐J) (IIIc) and Clausine O (IIId).
Authors: Kataeva Olga , Krahl Micha P. , Knoelker Hans‐Joachim 
Published: December 2005

AbstractFor Abstract see ChemInform Abstract in Full Text.
Isolation of Onosmins A and B, Lipoxygenase Inhibitors from Onosma hispida.
Authors: Ahmad Ijaz , Nawaz Sarfraz Ahmad , Afza Nighat , Malik Abdul , Fatima Itrat , Khan Sher Bahadar , Ahmad Manzoor , Choudhary Muhammad Iqbal 
Published: December 2005

AbstractFor Abstract see ChemInform Abstract in Full Text.
Eleven New 2‐Pyrones from a Fungi Imperfecti, Trichurus terrophilus, Found in a Screening Study Guided by Immunomodulatory Activity.
Authors: Fujimoto Haruhiro , Okamoto Yoshie , Sone Eriko , Maeda Satomi , Akiyama Kohki , Ishibashi Masami 
Published: December 2005

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Stereoselective Synthesis of C3—C12 Dihydropyran Portion of Antitumor Laulimalide Using Copper‐Catalyzed Oxonium Ylide Formation‐[2,3] Shift.
Authors: Yakura Takayuki , Muramatsu Wataru , Uenishi Jun'ichi 
Published: December 2005

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One‐Dimensional BiPO4 Nanorods and Two‐Dimensional BiOCl Lamellae: Fast Low‐Temperature Sonochemical Synthesis, Characterization, and Growth Mechanism.
Authors: Geng Jun , Hou Wen‐Hua , Lv Yi‐Nong , Zhu Jun‐Jie , Chen Hong‐Yuan 
Published: December 2005

AbstractFor Abstract see ChemInform Abstract in Full Text.
4‐[(4′‐Methylphenyl)sulfonyl] ‐1‐(triphenylphosphoranylidene)‐2‐butanone— A New Versatile Building Block for Substituted Divinyl Ketones in the Synthesis of Natural Products
Authors: De Risi Carmela 
Published: December 2005

AbstractFor Abstract see ChemInform Abstract in Full Text.
Xenon NMR as a Probe for Microporous and Mesoporous Solids, Polymers, Liquid Crystals, Solutions, Flames, Proteins, Imaging
Authors: Bartik Kristin , Choquet Philippe , Constantinesco Andre , Duhamel Guillaume , Fraissard Jacques , Hyacinthe Jean‐Noel , Jokisaari Jukka , Locci Emanuela , Lowery Thomas J. , Luhmer Michel , et al. et al. 
Published: December 2005

AbstractFor Abstract see ChemInform Abstract in Full Text.
The clinical phenotype of wild‐type, heterozygous, and homozygous JAK2V617F in polycythemia vera
Authors: Tefferi Ayalew , Lasho Terra L. , Schwager Susan M. , Strand Jacob S. , Elliott Michelle , Mesa Ruben , Li Chin‐Yang , Wadleigh Martha , Lee Stephanie J. , Gilliland D. Gary 
Published: December 2005

AbstractBACKGROUNDSeveral studies have recently reported on the occurrence of a JAK2V617F mutation in myeloid cells from the majority of patients with polycythemia vera (PV). The clinical relevance of this novel observation currently is under study.METHODSIn a single institutional study, mutation screening for JAK2V617F was performed in DNA derived from archived blood granulocytes from 63 consecutive patients with PV in whom current diagnostic criteria were strictly applied and the diagnosis confirmed by bone marrow histology.RESULTSThe JAK2V617F mutant allele was detected in 58 of the 63 patients (92%) with 21% homozygosity. The clinical phenotype of the five patients with the wild‐type allele was otherwise typical for the disease. A statistical comparison between JAK2V617F heterozygotes (n = 45 patients) and homozygotes (n = 13 patients) did not reveal any significant associations with regard to age, gender, leukocyte or platelet count at the time of diagnosis, duration of disease, or the incidences of thrombosis or bleeding. However, compared with their heterozygote counterparts, JAK2V617F homozygote patients displayed a significantly higher hemoglobin level at the time of diagnosis (P = 0.001), an increased incidence of pruritus (69% vs. 38%; P = 0.04), a higher rate of fibrotic transformation (23% vs. 2%; P = 0.009), and higher PRV‐1 transcript levels in their blood granulocytes (P = 0.07).CONCLUSIONSThe results of the current clinical study support previous laboratory observations that link JAK2V617F with the PV phenotype by demonstrating a mutant allele dose effect on erythrocytosis and clinical and laboratory features characteristic of PV. Cancer 2006. © 2005 American Cancer Society.
Clinically significant prognostic factors for differentiated thyroid carcinoma
Authors: Lundgren Catharina Ihre , Hall Per , Dickman Paul W. , Zedenius Jan 
Published: December 2005

AbstractBACKGROUNDDifferent scoring systems currently are being used to stratify patients with differentiated thyroid carcinoma (DTC) into risk groups. DTC is usually subdivided into papillary thyroid carcinoma (PTC) and follicular thyroid carcinoma (FTC). The objective of the current study was to identify those factors that predict long‐term unfavorable prognosis and to evaluate the predictive accuracy of the TNM staging system.METHODSThe authors conducted a nested case–control study within the cohort of all patients (n = 5123) diagnosed with DTC in Sweden between 1958–1987 who survived at least 1 year after diagnosis. One control, matched by age at diagnosis, gender, and calendar period, was randomly selected for each case (patients who died of DTC). All patients were classified at the time of diagnosis according to the TNM staging system. The effect of prognostic factors on DTC mortality was evaluated using conditional logistic regression.RESULTSPatients with widely invasive FTC experienced a significantly higher mortality compared with PTC patients. The grade of differentiation was found to influence mortality significantly. Patients with TNM Stage IV disease had a higher mortality rate compared with patients with Stage II disease (odds ratio [OR] = 9.1; 95% confidence interval [95% CI], 5.7–14.6). Patients with lymph node metastases experienced a higher mortality (OR = 2.5; 95% CI, 1.6–4.1) and patients with distant metastasis at the time of diagnosis were found to have a nearly 7‐fold higher mortality rate (OR = 6.6; 95% CI, 4.1–10.5). Incomplete surgical excision was associated with higher mortality, particularly in patients with Stage I disease.CONCLUSIONSIn the current study, the following were found to be clinically significant prognostic factors for patients with DTC: histopathologic subgroup, TNM staging including lymph node metastases and distant metastases, and completeness of the surgical excision.Cancer 2006. © 2005 American Cancer Society.
Sensitized Emission of Luminescent Lanthanide Complexes Based on 4‐Naphthalen‐1‐yl‐Benzoic Acid Derivatives by a Charge‐Transfer Process
Authors: Kim Yong Hee , Baek Nam Seob , Kim Hwan Kyu 
Published: December 2005

AbstractThe photophysical properties of 4‐naphthalen‐1‐yl‐benzoic acid ligands and their EuIII‐cored complexes were systematically investigated to elucidate the effective energy‐transfer pathway in luminescent lanthanide complexes. A series of 4‐naphthalen‐1‐yl‐benzoic acid ligands, such as 4‐naphthalen‐1‐yl‐benzoic acid (NA‐1), 4‐[4‐(4‐methoxyphenyl)‐naphthalen‐1‐yl]‐benzoic acid (NA‐2), and 4‐{4‐[4‐(4‐methoxyphenyl)‐naphthalen‐1‐yl]‐benzyloxy}‐benzoic acid (NA‐3), were synthesized and utilized for the synthesis of their EuIII‐cored complexes, corresponding to NAC‐1, NAC‐2, and NAC‐3. The fluorescence spectra of NA‐1 and NA‐2 show large Stokes shifts with increasing solvent polarity. These large Stokes shifts might be dominantly due to the formation of an intramolecular charge transfer (ICT) complex in the excited state. Also, the intensive luminescence of the EuIII ions by the photoexcitation of the ligand in NAC‐1 and NAC‐2 in polar solvents supports that the energy transfer from the ligand to the EuIII ion takes place efficiently. In the case of NA‐3, which has a CH2OPh group that acts as a blocking group, there is no dependence of the fluorescence spectrum on the solvent nature and no luminescence of the EuIII ions by the photoexcitation of the ligand, indicating no formation of the ICT state. This can be due to the fact that the formation of the ICT state in NA‐3 was prevented because the OCH2 group acts as a blocking group by interrupting the π‐conjugation between the benzoic acid and the naphthalene unit. From these photophysical studies, we suggest that the ICT state plays a very important role in the energy‐transfer pathway from the ligand to the EuIII ion. To our best knowledge, this is the first demonstration of sensitized emission of luminescent lanthanide complexes based on 4‐naphthalen‐1‐yl‐benzoic acid derivatives by the charge‐transfer process.
Tissue inhibitor of metalloproteinase 1 regulates matrix metalloproteinase activity during newt limb regeneration
Authors: Stevenson Tamara J. , Vinarsky Vladimir , Atkinson Donald L. , Keating Mark T. , Odelberg Shannon J. 
Published: December 2005

AbstractMatrix metalloproteinase (MMP) activity is important for newt limb regeneration. In most biological processes that require MMP function, MMP activity is tightly controlled by a variety of mechanisms, including the coexpression of natural inhibitors. Here, we show that gene expression of one such inhibitor, tissue inhibitor of metalloproteinase 1 (NvTIMP1), is upregulated during the wound healing and dedifferentiation stages of regeneration when several MMPs are at their maximal expression levels. Newt MMPs and NvTIMP1 also exhibit similar spatial expression patterns during the early stages of limb regeneration. NvTIMP1 inhibits the proteolytic activity of regeneration‐related newt MMPs and, like human TIMP1, can induce a weak mitogenic response in certain cell types. These results suggest that NvTIMP1 may be functioning primarily to maintain optimal levels of MMP activity during the early stages of limb regeneration, while possibly serving a secondary role as a mitogen. Developmental Dynamics 235:606–616, 2006. © 2005 Wiley‐Liss, Inc.
Dpp signaling down‐regulates the expression of VM32E eggshell gene during Drosophila oogenesis
Authors: Bernardi Fabio , Cavaliere Valeria , Andrenacci Davide , Gargiulo Giuseppe 
Published: December 2005

AbstractAmong the members of the Drosophila melanogaster vitelline membrane protein gene family, VM32E has the unique feature of being a component of both the vitelline and the endochorion layers. The VM32E gene is expressed at stage 10 of egg chamber development in the main body follicle cells, and it is repressed in the anterior and posterior follicle cells. Here, we show that this spatial restriction of VM32E gene expression is conserved in the D. pseudoobscura orthologous gene, suggestive of a conserved function of VM32E protein. The VM32E gene is not expressed in the centripetal migrating follicle cells, where the Decapentaplegic (Dpp) pathway is active in patterning the anterior eggshell structures. By analyzing the native VM32E gene and the activity of specific VM32E regulatory regions, in genetic backgrounds altering the Dpp pathway, we show that VM32E gene is negatively regulated by the Dpp signaling. Therefore, it appears that the Dpp signaling pathway executes its control on eggshell morphogenesis also by controlling the expression of eggshell structural genes. Developmental Dynamics 235:768–775, 2006. © 2005 Wiley‐Liss, Inc.
Novel Carbonyliridium and ‐rhodium Complexes Containing 2,6‐Bis[(4′S)‐4′‐isopropyloxazolin‐2′‐yl]pyridine (iPr‐pybox) and 2,6‐Bis[(4′R)‐4′‐phenyloxazolin‐2′‐yl]pyridine (Ph‐pybox) Ligands
Authors: Cuervo Darío , Díez Josefina , Gamasa M. Pilar , Gimeno José , Paredes Paloma 
Published: December 2005

AbstractThe iridium(I) complexes [Ir(CO)(κ3‐N,N,N‐R‐pybox)][PF6] [R‐pybox = (S,S)‐iPr‐pybox (1), (R,R)‐Ph‐pybox (2)] have been prepared by reaction of their precursor complexes [Ir(η2‐C2H4)2(κ3‐N,N,N‐R‐pybox)][PF6] (R = iPr or Ph) with carbon monoxide. The analogous carbonylrhodium(I) complexes [Rh(CO)(κ3‐N,N,N‐R‐pybox)][PF6] [R‐pybox = (S,S)‐iPr‐pybox (3), (R,R)‐Ph‐pybox (4)] have been synthesised by reaction of [Rh(μ‐Cl)(η2‐C2H4)2]2, carbon monoxide, R‐pybox and NaPF6. Complexes 1–4 undergo oxidative addition reactions with iodine and CH3I leading, with high stereoselectivity, to the complexes [MI(X)(CO)(κ3‐N,N,N‐R‐pybox)][PF6] [M = Ir, R = iPr, X = I (5); M = Rh, R = iPr, X = I (6); M = Rh, R = Ph, X = I (7); M = Ir, R = iPr, X = CH3 (8); M = Ir, R = Ph, X = CH3 (9); M = Rh, R = iPr, X = CH3 (10); M = Rh, R = Ph, X = CH3 (11)]. The treatment of complexes 1 and 2 with HCl, allyl chloride or acyl chloride results, in most cases, in the stereoselective formation of the iridium(III) complexes [IrHCl(CO)(κ3‐N,N,N‐R‐pybox)][PF6] [R = iPr (12), Ph (13)], [IrCl(η1‐CH2CH=CH2)(CO)(κ3‐N,N,N‐R‐pybox)][PF6] [R = iPr (14), Ph (15)] or [IrCl{η1‐C(O)CH3}(CO)(κ3‐N,N,N‐R‐pybox)][PF6] [R = iPr (16), Ph (17)], respectively. The structures of derivatives 10 and 15 have been determined by single‐crystal X‐ray diffraction analysis. The catalytic activity of monocarbonylrhodium(I) and ‐iridium(I) complexes 1 and 3 in the hydrosilylation and dehydrosilylation of acetophenone with diphenylsilane has also been examined. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2006)
Pyrophosphate and ATP as Stabilizing Ligands for High‐Valent Nickel Complexes
Authors: Shamir Dror , Zilbermann Israel , Maimon Eric , Shames Alexander I. , Cohen Haim , Meyerstein Dan 
Published: December 2005

AbstractATP stabilizes trivalent nickel complexes which suggests that another plausible role of ATP in biological systems is the stabilization of high‐valent transition metal complexes. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2006)
Gram‐Scale Preparation of a p‐(C‐Glucopyranosyl)‐L‐phenylalanine Derivative by a Negishi Cross‐Coupling Reaction
Authors: Ousmer Malika , Boucard Valérie , Lubin‐Germain Nadège , Uziel Jacques , Augé Jacques 
Published: December 2005

AbstractA p‐(C‐glucopyranosyl)‐L‐phenylalanine derivative protected to be directly incorporated into a peptidic chain is prepared in 37 % yield from glucose on a gram scale, with a Negishi cross‐coupling reaction as the key step. Zincated glucal and p‐iodo‐L‐phenylalanine are involved in this organometallic coupling, which gives rise to a link between the sugar and amino acid moieties in 90 % yield; the β‐gluco configuration of the C‐glycopyranosyl amino acid is ascertained by a stereoselective hydroboration of the double bond of the glucal. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2006)