bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effects of postoperative administration of ketoprofen or carprofen on short- and long-term results of femoral head and neck excision in dogs
Authors: Grisneaux Emmanuelle , Dupuis Jacques , Pibarot Philippe , Bonneau Norbert H. , Charette Benoît , Blais Diane 
Published: January 2006

AbstractObjective—To determine whether postoperative administration of ketoprofen or carprofen had any effects on short- or long-term results of femoral head and neck excision (FHNE) in dogs.Design—Prospective randomized controlled trial.Animals—40 client-owned, large-breed dogs undergoing FHNE and 15 healthy large-breed dogs used as controls for hip joint angle measurements and force plate analyses.Procedure—Dogs undergoing FHNE were treated with ketoprofen, carprofen, or a placebo for 21 days after surgery. Hip joint abduction and extension angles were measured at the end of surgery and 120 days later. Lameness scores were assigned, and force plate analyses were performed on days 3, 15, and 120.Results—There were no significant differences among treatment groups in regard to hip joint angles or lameness scores. Force plate analysis revealed that dogs in all 3 treatment groups bore consistently less weight on the operated limb than did control dogs for the duration of the study. Dogs receiving ketoprofen had greater peak propulsive force at a walk on day 3 and greater peak vertical force at a walk on day 15 than did dogs receiving the placebo. Treatment of an acute condition and preservation of the lesser trochanter, but not postoperative analgesic administration, were positively associated with ground reaction forces on day 120. Owners of 12 of 31 dogs indicated that the dog's gait worsened for a few days after discontinuation of analgesic administration.Conclusions and Clinical Relevance—Administration of ketoprofen or carprofen after surgery was not associated with long-term results of FHNE, probably because of the impact of other factors. Because some owners noticed worsening of the lameness following cessation of analgesic administration in the present study, it is possible that longer administration would have improved long-term results. (J Am Vet Med Assoc2003;223:1006–1012)
Minimum alveolar concentration of sevoflurane in spontaneously breathing llamas and alpacas
Authors: Grubb Tamara L. , Schlipf John W. , Riebold Thomas W. , Cebra Christopher K. , Poland Lisa , Zawadzkas Xenia , Mailhot Nicole 
Published: January 2006

AbstractObjective—To determine the minimum alveolar concentration (MAC) of sevoflurane in spontaneously breathing llamas and alpacas.Design—Prospective study.Animals—6 healthy adult llamas and 6 healthy adult alpacas.Procedure—Anesthesia was induced with sevoflurane delivered with oxygen through a mask. An endotracheal tube was inserted, and a port for continuous measurement of end-tidal and inspired sevoflurane concentrations was placed between the endotracheal tube and the breathing circuit. After equilibration at an end-tidal-to-inspired sevoflurane concentration ratio > 0.90 for 15 minutes, a 50-Hz, 80-mA electrical stimulus was applied to the antebrachium until a response was obtained (ie, gross purposeful movement) or for up to 1 minute. The vaporizer setting was increased or decreased to effect a 10 to 20% change in end-tidal sevoflurane concentration, and equilibration and stimulus were repeated. The MAC was defined as the mean of the lowest end-tidal sevoflurane concentration that prevented a positive response and the highest concentration that allowed a positive response.Results—Mean ± SD MAC of sevoflurane was 2.29 ± 0.14% in llamas and 2.33 ± 0.09% in alpacas. Conclusions and Clinical Relevance—The MAC of sevoflurane in llamas and alpacas was similar to that reported for other species. (J Am Vet Med Assoc2003;223:1167–1169)
Comparison of injuries in sows housed in gestation stalls versus group pens with electronic sow feeders
Authors: Anil Leena , Bhend Kristy M. G. , Baidoo Samuel K. , Morrison Rebecca , Deen John 
Published: January 2006

AbstractObjective—To compare the location and severity of injuries in pregnant sows housed in individual gestation stalls with that in pregnant sows housed in dynamic groups in pens with electronic sow feeders.Design—Prospective study.Animals—100 pregnant sows of parity 1 to 3 and various body weights.Procedure—Fifty sows each were randomly allotted to gestation stalls or group pens with electronic sow feeders. Injuries were scored on the basis of location, number, and depth of wounds. Injury scores for sows in both housing systems were compared during a period of 90 days. The influence of factors such as duration of stay in the housing system, parity, and body weight on sow injuries was also examined.Results—Injury scores were higher in group pens with electronic sow feeders. As body weight increased, injury scores decreased for sows housed in group pens with electronic sow feeders and increased for sows housed in gestation stalls. There was a significant negative association between second parity and total injury scores.Conclusions and Clinical Relevance—Modifications in housing system design and management procedures are needed to reduce injuries in pregnant sows. (J Am Vet Med Assoc2003;223:1334–1338)
Age-related variations in hematologic and plasma biochemical test results in Beagles and Labrador Retrievers
Authors: Harper E. Jean , Hackett Rachel M. , Wilkinson Joy , Heaton Paul R. 
Published: January 2006

Abstract

Objective—To investigate age-related variations in
results of hematologic and plasma biochemical tests
performed on dogs of 2 common breeds.

Design—Prospective cohort study.

Animals—34 Beagles and 44 Labrador Retrievers.

Procedure—Blood samples were collected throughout
the dogs' lives; 589 samples were collected from
the Beagles and 964 samples were collected from
the Labrador Retrievers (age at the time of sample
collection ranged from 22 days to 15 years). White
blood cell and RBC counts; hemoglobin concentration;
Hct; mean cell volume; mean cell hemoglobin
concentration; alkaline phosphatase, alanine aminotransferase,
and aspartate aminotransferase activities;
and calcium, phosphorus, cholesterol, urea, protein,
and albumin concentrations were measured.

Results—For all tests, there were significant effects
of age on test results. There was a significant interaction
between age and breed for all tests except
hemoglobin, albumin, and phosphorus concentrations.

Conclusions and Clinical Relevance—Results suggested
that there were age-related changes in hematologic
and plasma biochemical test results in these 2
breeds of dogs. Changes were most evident during
the first year of life, reflecting growth and maturation
of the puppies. In some instances, values for puppies
diverged markedly from those for adults, necessitating
the use of age-specific reference ranges for the
interpretation of clinical data. (J Am Vet Med Assoc 2003;223:1436–1442)
Foal-related risk factors associated with development of Rhodococcus equi pneumonia on farms with endemic infection
Authors: Chaffin M. Keith , Cohen Noah D. , Martens Ronald J. , Edwards Ronnie F. , Nevill Mark 
Published: January 2006

AbstractObjective—To identify foal-related risk factors associated with development ofRhodococcus equipneumonia among foals on farms with endemicR equiinfection.Design—Prospective case-control study.Animals—220 foals at 2 equine breeding farms in Texas during a 2-year period.Procedure—Information collected for each dam included age, time housed on the farm prior to parturition, whether there were any peripartum illnesses, parity, and health of previous foals. Information collected for each foal included breed, sex, gestational age, month and year of birth, location of birth, type of flooring and bedding in stall, postpartum management and preventive health care, passive immunity status, supplementation of immunoglobulins, exposure to other farms or foals affected withR equipneumonia, stall and pasture exposure, commingling with other mare-foal pairs, age at weaning, and whether the foal developedR equipneumonia.Results—32 of the 220 (15%) foals developedR equipneumonia, of which 4 (13%) died. Foals at 1 of the 2 farms and foals born during the second year of the study were more likely to developR equipneumonia. Foal-related factors that were examined were not significantly associated with risk ofR equipneumonia in multivariate analyses.Conclusions and Clinical Relevance—Results suggest that there are farm- and year-related effects on the risk that foals will developR equipneumonia. Other foal-related factors significantly associated withR equipneumonia were not identified. (J Am Vet Med Assoc2003;223:1791–1799)
Use of a three-drill-tract technique for arthrodesis of the distal tarsal joints in horses with distal tarsal osteoarthritis: 54 cases (1990–1999)
Authors: Dechant Julie E. , Baxter Gary M. , Southwood Louise L. , Crawford William H. , Jackman Bradley R. , Stashak Ted S. , Trotter Gayle W. , Hendrickson Dean A. 
Published: January 2006

AbstractObjective—To assess the long-term clinical outcome of horses with distal tarsal osteoarthritis (OA) in which a 3-drill-tract technique was used to induce arthrodesis of the affected joints, identify any preoperative or operative factors associated with outcome, and describe any complications associated with the technique.Design—Retrospective study.Animals—54 horses.Procedure—Medical records were reviewed for information on signalment, use, history, physical and lameness examination findings, surgical technique, and postoperative care. Radiographs were examined, and severity of OA was graded. Follow-up information was obtained through telephone interviews with owners at least 13 months after the procedure.Results—32 (59%) horses had a successful outcome, 6 (11%) improved but were not sound after surgery, and 16 (30%) did not improve following surgery. Outcome was negatively associated with the previous use of intra-articular injections. Few postoperative complications were evident.Conclusions and Clinical Relevance—Results suggest that distal tarsal OA in horses can be successfully treated by means of distal tarsal arthrodesis with a 3-drill-tract technique. Horses with advanced distal tarsal OA are likely to have poorer outcomes, and the procedure will likely be of minimal benefit in horses with concomitant causes of hind limb lameness prior to surgery and in horses with preexisting proximal intertarsal joint disease. (J Am Vet Med Assoc2003; 223;1800–1805)
Efficacy and safety of topical administration of selamectin for treatment of ear mite infestation in rabbits
Authors: McTier Tom L. , Hair J. Alexander , Walstrom Douglas J. , Thompson Leland 
Published: January 2006

AbstractObjective—To evaluate the efficacy and safety of topical administration of selamectin in rabbits naturally infested withPsoroptes cuniculi.Design—Randomized controlled trial.Animals—48 mixed-breed domestic rabbits with activeP cuniculimite populations and clinical ear lesions.Procedures—Rabbits were randomly allocated to 1 of 6 treatment groups. On day 0, rabbits in groups 1 and 2 were given vehicle, rabbits in groups 3 and 4 were given selamectin at a dose of 6 mg/kg (2.7 mg/lb), and rabbits in groups 5 and 6 were given selamectin at a dose of 18 mg/kg (8.2 mg/lb). On day 28, rabbits in groups 2, 4, and 6 were given a second dose of vehicle or selamectin. Otoscopic examinations were performed and ear lesion size was measured weekly for 8 weeks. Quantitative viable mite counts were performed on day 56.Results—On days 7 through 56, lesion sizes for all selamectin-treated groups were significantly lower than sizes for control groups; there were no significant differences in lesion sizes among selamectintreated groups. All rabbits in the 2 control groups had viable adultP cuniculimites for the duration of the study, as determined by otoscopic examination, whereas all rabbits in the 4 selamectin-treated groups were free fromP cuniculimites on days 7 through 56. No adverse reactions associated with selamectin treatment were observed.Conclusions and Clinical Relevance—Results suggest that topical application of selamectin at a dose of 6 or 18 mg/kg can completely eliminate mites from rabbits naturally infested withP cuniculi. (J Am Vet Med Assoc2003;223:322–324)
Evaluation of prevalence and clinical implications of anthelmintic resistance in gastrointestinal nematodes in goats
Authors: Mortensen Lars L. , Williamson Lisa H. , Terrill Thomas H. , Kircher Robin A. , Larsen Michael , Kaplan Ray M. 
Published: January 2006

AbstractObjective—To determine prevalence of resistance to all anthelmintics that are commonly used to treat gastrointestinal nematodes (GINs) in goats.Design—Prospective study.Animals—777 goats.Procedure—On each farm, goats were assigned to 1 of 5 treatment groups: untreated controls, albendazole (20 mg/kg [9.0 mg/lb], PO, once), ivermectin (0.4 mg/kg [0.18 mg/lb], PO, once), levamisole (12 mg/kg [5.4 mg/lb], PO, once), or moxidectin (0.4 mg/kg, PO, once), except on 3 farms where albendazole was omitted. Fecal samples were collected 2 weeks after treatment for determination of fecal egg counts (FECs), and percentage reductions were calculated by comparing data from anthelmintic-treated and control groups. Nematode populations were categorized as susceptible, suspected resistant, or resistant by use of guidelines published by the World Association for the Advancement of Veterinary Parasitology.Results—Resistance to albendazole was found on 14 of 15 farms, and resistance to ivermectin, levamisole, and moxidectin was found on 17, 6, and 1 of 18 farms, respectively. Suspected resistance to levamisole and moxidectin was found on 4 and 3 farms, respectively. Resistance to multiple anthelmintics (albendazole and ivermectin) was found on 14 of 15 farms and to albendazole, ivermectin, and levamisole on 5 of 15 farms. Mean overall FEC reduction percentages for albendazole, ivermectin, levamisole, and moxidectin were 67, 54, 94, and 99%, respectively.Conclusions and Clinical Relevance—Anthelmintic resistance in GINs of goats is highly prevalent in the southern United States. The high prevalence of resistance to multiple anthelmintics emphasizes the need for reexamination of nematode control practices. (J Am Vet Med Assoc2003;223:495–500)
Evaluation of association between retention in the home and attendance at puppy socialization classes
Authors: Duxbury Margaret M. , Jackson Julie A. , Line Scott W. , Anderson Robert K. 
Published: January 2006

AbstractObjective—To evaluate associations between retention of dogs in their adoptive homes and attendance at puppy socialization classes and other factors.Design—Epidemiologic survey.Animals—248 adult dogs that were adopted as puppies from a humane society.Procedure—Owners completed questionnaires regarding demographics, retention of the dogs in the homes, and the dogs' early learning events.Results—Higher retention in the homes was reported for dogs that participated in humane society puppy socialization classes, were female, wore headcollars as puppies, were handled frequently as puppies, were more responsive to commands, slept on or near the owner's bed, or lived in homes without young children.Conclusions and Clinical Relevance—Results suggest several practices that veterinarians may recommend to enhance the likelihood that puppies will remain in their first homes, such as enrolling 7- to 12-week-old puppies in early learning and socialization classes. The lower rate of retention of dogs in homes with children emphasizes the importance of helping owners develop realistic expectations, knowledge, and effective tools to manage interactions between their children and dogs. (J Am Vet Med Assoc2003; 223:61–66)
Efficacy of selamectin in the treatment and control of clinical signs of flea allergy dermatitis in dogs and cats experimentally infested with fleas
Authors: Dickin Sandy K. , McTier Tom L. , Murphy Martin G. , Bond Ross , Mason Ian S. , Payne-Johnson Mark , Smith David G. , Evans Nigel A. , Jernigan Ann D. , Rowan Tim G. 
Published: January 2006

Abstract

Objective—To determine whether treatment with
selamectin would reduce clinical signs of flea allergy
dermatitis (FAD) in dogs and cats housed in flea-infested
environments.

Design—Randomized controlled trial.

Animals—22 dogs and 17 cats confirmed to have FAD.

Procedure—Animals were housed in carpeted pens
capable of supporting the flea life cycle and infested
with 100 fleas (Ctenocephalides felis) on days –13 and
–2 and on alternate weeks with 10 to 20 fleas. On day
0, 11 dogs and 8 cats were treated with selamectin (6
mg/kg [2.7 mg/lb]). Dogs were retreated on day 30;
cats were retreated on days 30 and 60. All animals
were examined periodically for clinical signs of FAD.
Flea counts were conducted at weekly intervals.

Results—Throughout the study, geometric mean flea
counts exceeded 100 for control animals and were ≤ 11
for selamectin-treated animals. Selamectin-treated
cats had significant improvements in the severity of
miliary lesions and scaling or crusting on days 42 and
84, compared with conditions on day –8, and in severity
of excoriation on day 42. In contrast, control cats did
not have any significant improvements in any of the
clinical signs of FAD. Selamectin-treated dogs had significant
improvements in all clinical signs on days 28
and 61, but in control dogs, severity of clinical signs of
FAD was not significantly different from baseline severity
at any time.

Conclusions and Clinical Relevance—Results suggest
that topical administration of selamectin, even without
the use of supplementary environmental control
measures and with minimal therapeutic intervention,
can reduce the severity of clinical signs of FAD in dogs
and cats. (J Am Vet Med Assoc 2003;223:639–644)
Case-control study of factors associated with fibrinous pericarditis among horses in central Kentucky during spring 2001
Authors: Seahorn Janyce L. , Slovis Nathan M. , Reimer Johanna M. , Carey Vincent J. , Donahue James G. , Cohen Noah D. 
Published: January 2006

AbstractObjective—To identify factors significantly associated with an epidemic of fibrinous pericarditis during spring 2001 among horses in central Kentucky.Design—Case-control study.Animals—38 horses with fibrinous pericarditis and 30 control horses examined for other reasons.Procedure—A questionnaire was developed to solicit information regarding a wide range of management practices and environmental exposures from farm owners or managers.Results—The following factors were found in bivariate analyses to be significantly associated with an increased risk of pericarditis: being from a farm with mares and foals affected by mare reproductive loss syndrome, exposure to Eastern tent caterpillars in or around horse pastures, younger age, shorter duration of residence in Kentucky and at the farm of current residence, being fed hay grown outside Kentucky, a lack of access to pond water, access to orchard grass for grazing, and a lack of direct contact with cattle. In multivariate logistic regression analyses, only variables related to caterpillar exposure and age were significantly associated with fibrinous pericarditis.Conclusions and Clinical Relevance—Results suggest that fibrinous pericarditis in horses may be associated with mare reproductive loss syndrome. Exposure to Eastern tent caterpillars was the greatest risk factor for development of fibrinous pericarditis. The distribution of times of diagnosis of fibrinous pericarditis was consistent with a point-source epidemic. (J Am Vet Med Assoc2003;223:832–838)
Retroperitoneal sarcomas in dogs: 14 cases (1992–2002)
Authors: Liptak Julius M. , Dernell William S. , Ehrhart Eugene J. , Rizzo Scott A. , Rooney Matthew B. , Withrow Stephen J. 
Published: January 2006

AbstractObjective–To describe the clinical features, surgical and histologic findings, biological behavior, and outcome of dogs with retroperitoneal sarcomas.Design–Retrospective study.Animals–14 dogs.Procedures–Medical and pathology records from 1992 to 2002 of dogs with tumors originating in the retroperitoneal space were reviewed. Dogs with retroperitoneal tumors originating from the adrenal glands, kidneys, or ureters were excluded. Inclusion criteria included observation of a tumor arising from the retroperitoneal space during exploratory surgery or necropsy and histologic confirmation of tumor type. Details of clinical signs, diagnostic findings, surgical management, and outcome were determined from medical records and telephone interviews with veterinarians and owners.Results–Retroperitoneal sarcoma was diagnosed in 14 dogs, 2 at necropsy and 12 during exploratory surgery. Hemangiosarcoma was the most common histologic diagnosis. Seven dogs had regional extension of the sarcoma into adjacent organs, and 4 dogs had metastatic disease. Grossly complete resection was possible in 6 dogs. Cytoreductive surgery or incisional biopsy was performed in the remaining dogs. Two dogs were treated with palliative radiation therapy (1 intraoperatively and 1 postoperatively). Three dogs received adjunctive chemotherapy, although none completed the targeted course because of development of local recurrence or metastatic disease. Local recurrence was reported in 2 of 12 dogs and metastasis in 10 of 14 dogs. Thirteen dogs died or were euthanatized as a result of the retroperitoneal sarcoma; 1 dog was alive and disease-free 410 days after surgery. Median survival time was 37.5 days.Conclusions and Clinical Relevance–In dogs, retroperitoneal sarcomas are aggressive tumors with a high rate of local recurrence and metastasis, and a poor survival time. (J Am Vet Med Assoc2004;224: 1471–1477)
Effects of passive transfer of immunity on results of diagnostic tests for antibodies against feline immunodeficiency virus in kittens born to vaccinated queens
Authors: MacDonald Kristin , Levy Julie K. , Tucker Sylvia J. , Crawford P. Cynda 
Published: January 2006

AbstractObjective—To determine whether passive transfer of immunity affects results of diagnostic tests for antibodies against FIV in kittens born to vaccinated queens.Design—Experimental trial.Animals—12 specific-pathogen-free queens and their 55 kittens.Procedure—Queens were vaccinated with a wholevirus FIV vaccine prior to breeding. Serum was obtained from the queens on the day of parturition and from the kittens on days 2 and 7, then weekly until results of tests for antibodies against FIV were negative for 2 consecutive weeks. Milk was collected from the queens daily for the first week and then weekly. Serum and milk were tested for antibodies against FIV with 2 commercial assays.Results—Antibodies against FIV were detected in serum obtained from the queens on the day of parturition and in the milk throughout lactation. All kittens tested positive for antibodies against FIV at 2 days of age. At 8 weeks of age, 30 (55%) kittens tested positive with 1 of the commercial assays, and 35 (64%) tested positive with the other. All kittens tested negative for antibodies against FIV by 12 weeks of age.Conclusions and Clinical Relevance—Results suggest that kittens readily absorb antibodies against FIV in colostrum from vaccinated queens and that these antibodies may interfere with results of commercially available tests for FIV infection past the age of weaning. Currently licensed diagnostic tests for FIV infection are unable to distinguish among kittens with antibodies against FIV as a result of infection, passive transfer from infected queens, and passive transfer from vaccinated queens. (J Am Vet Med Assoc2004;225:1554–1557)