bluuebunny/crossref_metadata_2025_split huggingface dataset:
Morphological aspects of surgical meshes as a risk factor for bacterial colonization
Authors: Engelsman A F , van der Mei H C , Busscher H J , Ploeg R J 
Published: July 2008

AbstractBackgroundProsthetic meshes are increasingly popular in abdominal wall reconstructive surgery owing to a reduction in hernia recurrence rate. Individual meshes have been evaluated with respect to the formation of infectious biofilms, but no comprehensive comparison yet exists. The aim of this study was to evaluate the effect of the material and morphology of surgical meshes on biofilm growth.MethodsBiofilms of a coagulase-negative staphylococcus, Staphylococcus aureus, Escherichia coli and Pseudomonas aeruginosa were grown in vitro on different meshes. Intact biofilms were stained fluorescently and evaluated with confocal laser scanning microscopy to distinguish dead from live bacteria and slime.ResultsNumbers of adhering bacteria and the amount of slime in the biofilm were dependent on the morphology of the mesh. Hydrophobicity and the presence of niches in multifilament meshes contributed most to increased biofilm growth.ConclusionThe morphological properties of surgical meshes as well as their hydrophobicity influence bacterial growth and slime production. Differences in slime production may explain why the effectiveness of antibiotic treatment varies for different types of mesh.
New Developments in Umami (Enhancing) Molecules
Authors: Winkel Chris , de Klerk Adri , Visser Jan , de Rijke Eva , Bakker Jan , Koenig Thorsten , Renes Harry 
Published: July 2008

AbstractAs health has become one of the main drivers in nutrition, the scientific interest in taste receptors and taste molecules has increased considerably. Academia as well as flavor and food companies are searching for molecules that make food more healthy but not less appetizing. In the savory area, salt and umami taste are being investigated. This review deals with the progress made in umami tasting molecules. Umami taste has been known as a separate taste for a long time in Asian countries and has been generally accepted as the fifth basic taste in the last decade of the previous century. In this review, first the current level of understanding of the umami receptors will be described. The main part of the paper will deal with the umami‐tasting molecules that have been published recently, including the work that has been performed within Givaudan itself. Lactoyl amides of GMP (guanosine monophosphate) appeared to have remarkably strong umami‐tasting properties.
The Anthelmintic Activity of the Cyclotides: Natural Variants with Enhanced Activity
Authors: Colgrave Michelle L. , Kotze Andrew C. , Ireland David C. , Wang Conan K. , Craik David J. 
Published: July 2008

AbstractThe cyclotides are a family of backbone‐cyclised cystine‐knot‐containing peptides from plants that possess anthelmintic activity against Haemonchus contortus and Trichostrongylus colubriformis, two important gastrointestinal nematode parasites of sheep. In the current study, we investigated the in vitro effects of newly discovered natural cyclotides on the viability of larval and adult life stages of these pests. The natural variants cycloviolacin O2, cycloviolacin O3, cycloviolacin O8, cycloviolacin O13, cycloviolacin O14, cycloviolacin O15, and cycloviolacin O16 extracted from Viola odorata showed up to 18‐fold greater potency than the prototypic cyclotide kalata B1 in nematode larval development assays. Cycloviolacin O2 and cycloviolacin O14 were significantly more potent than kalata B1 in adult H. contortus motility assays. The lysine and glutamic acid residues of cycloviolacin O2, the most potent anthelmintic cyclotide, were chemically modified to investigate the role of these charged residues in modulating the biological activity. The single glutamic acid residue, which is conserved across all known cyclotides, was shown to be essential for activity, with a sixfold decrease in potency of cycloviolacin O2 following methylation. The three lysine residues present in cycloviolacin O2 were acetylated to effectively mask the positive charge, resulting in a 18‐fold decrease in anthelmintic activity. The relative anthelmintic activities of the natural variants assayed against nematode larvae correlated with the number of charged residues present in their sequence.
Construction of a pH‐Responsive Artificial Membrane Fusion System by Using Designed Coiled‐Coil Polypeptides
Authors: Kashiwada Ayumi , Matsuda Kiyomi , Mizuno Toshihisa , Tanaka Toshiki 
Published: July 2008

AbstractIn many viruses, pH‐responsive coiled‐coil domains in the specific fusion proteins play important roles in membrane fusion and the infection of viruses into host cells. To investigate the relationship between the conformational change of the coiled coil and the fusion process, we have introduced a de novo designed polypeptide as a model system of the coiled‐coil domain. This system enables the systematic study of the dynamics of pH‐responsive coiled‐coil polypeptide–membrane interactions. First, we designed and synthesized pH‐responsive isoleucine‐zipper triple‐stranded coiled‐coil polypeptides. Then the relationship between the pH‐induced conformational change of the polypeptide and the membrane's interactive properties was studied by physicochemical methods. Structural changes in the designed polypeptides were examined by means of circular dichroism measurements. And finally, the behavior of the membrane fusion was investigated by leakage of liposomal contents, turbidity analysis, dynamic light scattering, and lipid mixing experiments. Our data show that coiled‐coil formation under acidic pH conditions enhances polypeptide‐induced membrane fusion. The results in this study demonstrate that an artificial membrane fusion system can be constructed on a molecular level by the use of a pH‐responsive isoleucine‐zipper triple‐stranded coiled‐coil polypeptide.
Synthesis, Surface Modifications, and Size‐Sorting of Mixed Nickel–Zinc Ferrite Colloidal Magnetic Nanoparticles
Authors: Majewski P. , Krysiński P. 
Published: July 2008

AbstractWe report on the spontaneous covalent growth of monomolecular adlayers on mixed nickel–zinc nanoferrite colloidal suspensions (ferrofluids). Synthesized nanoparticles were subjected to surface modification by means of acid chloride chemistry, leading to the formation of covalent bonds between the hydroxy groups at the nanoparticle surface and the acid chloride molecules. This procedure can be easily tailored to allow for the formation of adlayers containing both hydrophobic and hydrophilic regions stacked at predetermined distances from the magnetic core, and also providing the nanoferrites with functional carboxy groups capable of further modifications with, for example, drug molecules. Here, fluorophore aminopyrene molecules were bound to such modified nanoferrites through amide bonds. We also used the same chemistry to modify the surface with covalently bound long‐chain palmitoyl moieties, and for comparison we also modified the nanoferrite surface by simple adsorption of oleic acid. Both procedures made the surface highly hydrophobic. These hydrophobic colloids were subsequently spread on an aqueous surface to form Langmuir monolayers with different characteristics. Moreover, since uniformity of size is crucial in a number of applications, we propose an efficient way of sorting the magnetic nanoparticles by size in their colloidal suspension. The suspension is centrifuged at increasing rotational speed and the fractions are collected after each run. The mean size of nanoferrite in each fraction was measured by the powder X‐ray diffraction (PXRD) technique.
One‐Pot Organocatalytic Domino Michael/α‐Alkylation Reactions: Direct Catalytic Enantioselective Cyclopropanation and Cyclopentanation Reactions
Authors: Ibrahem Ismail , Zhao Gui‐Ling , Rios Ramon , Vesely Jan , Sundén Henrik , Dziedzic Pawel , Córdova Armando 
Published: July 2008

AbstractThe development of one‐pot organocatalytic domino Michael/α‐alkylation reactions between bromomalonates or bromoacetoacetate esters and α,β‐unsaturated aldehydes is presented. The chiral‐amine‐catalyzed reactions with bromomalonates as substrates give access to the corresponding 2‐formylcyclopropane derivatives in high yields with excellent diastereoselectivity and up to 99 % ee. The catalytic domino Michael/α‐alkylation reactions between 4‐bromo‐acetoacetate and enals provide a route for the synthesis of functionalized cyclopentanones in good to high yields with 93–99 % ee. The products from the organocatalytic reactions were also reduced with high diastereoselectivity to the corresponding cyclopropanols and cyclopentanols, respectively. Moreover, one‐pot combinations of amine and heterocyclic carbene catalysis (AHCC) enabled the highly enantioselective synthesis of β‐malonate esters (91–97 % ee) from the reaction between bromomalonates and enals. The tandem catalysis included the catalytic domino reaction followed by catalytic in situ chemoselective ring‐opening of the 2‐formylcyclopropane intermediates.
ChemInform Abstract: Synthesis and Characterization of a New Organically Templated Zincophosphate: (C2N2H10)2 [Zn(PO4)2].
Authors: Mao Shao‐Yu , Xie Yu , Xie Zhao‐Xiong , Zhao Jing‐Tai 
Published: July 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Self‐Assembled 3D Architectures of LuBO3:Eu3+: Phase‐Selective Synthesis, Growth Mechanism, and Tunable Luminescent Properties.
Authors: Yang Jun , Li Chunxia , Zhang Xiaoming , Quan Zewei , Zhang Cuimiao , Li Huaiyong , Lin Jun 
Published: July 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis and Characterization of the First 1‐D Borate Templated by Transition Metal Complex.
Authors: Wang Guo‐Ming , Li Jin‐Hua , Li Zeng‐Xin , Wang Pei , Li Hui 
Published: July 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Reaction of N‐Nonaflyl and N‐Cyano‐benzotriazoles with Enamines.
Authors: Uhde Moritz , Anwar Muhammad Usman , Ziegler Thomas 
Published: July 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Heteropoly Acids: A Green and Efficient Heterogeneous Broensted Acidic Catalyst for the Intermolecular Hydroamination of Olefins.
Authors: Yang Lei , Xu Li‐Wen , Xia Chun‐Gu 
Published: July 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Cu‐Catalyzed Regioselective Carbomagnesiation of Dienes and Enynes with sec‐ and tert‐Alkyl Grignard Reagents.
Authors: Todo Hirohisa , Terao Jun , Watanabe Hideyuki , Kuniyasu Hitoshi , Kambe Nobuaki 
Published: July 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: An Efficient Synthesis of Some 5‐Substituted‐3‐methyl‐2‐cyclohexen‐1‐ones Using Microwaves.
Authors: Jyothi Divya , Prasad S. Hari 
Published: July 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Organocatalytic Highly Enantioselective Conjugate Addition of Aldehydes to Alkylidene Malonates.
Authors: Zhao Gui‐Ling , Vesely Jan , Sun Junliang , Christensen Kirsten E. , Bonneau Charlotte , Cordova Armando 
Published: July 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Catalytic Asymmetric Alkylations of Ketoimines. Enantioselective Synthesis of N‐Substituted Quaternary Carbon Stereogenic Centers by Zr‐Catalyzed Additions of Dialkylzinc Reagents to Aryl‐, Alkyl‐, and Trifluoroalkyl‐Substituted Ketoimines.
Authors: Fu Peng , Snapper Marc L. , Hoveyda Amir H. 
Published: July 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Organocatalytic Synthesis of N‐Phenylisoxazolidin‐5‐ones and a One‐Pot Synthesis of β‐Amino Acid Esters.
Authors: Seayad Jayasree , Patra Pranab Kumar , Zhang Yugen , Ying Jackie Y. 
Published: July 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis and Cytotoxic Activity of Resveratrol‐Based Compounds.
Authors: Handler Norbert , Saiko Philipp , Jaeger Walter , Szekeres Thomas , Wacheck Volker , Berner Heinz , Leisser Klaus , Erker Thomas 
Published: July 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis and Characterization of 2,9‐Bis(perfluorobutyl)pentacene (VI) as an n‐Type Organic Field‐Effect Transistor.
Authors: Okamoto Kazuo , Ogino Kenji , Ikari Mitsuaki , Kunugi Yoshihito 
Published: July 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: 5‐Chloro‐7‐iodo‐8‐quinolinolatomanganese(III) with the Feature of pH‐Regulated Molecular Switches as a Highly Efficient Catalyst for Epoxidation of Olefins with Hydrogen Peroxide.
Authors: Zhong Sheng , Fu Zaihui , Tan Yueming , Xie Qingji , Xie Fang , Zhou Xiaoping , Ye Zhengpei , Peng Guosheng , Yin Dulin 
Published: July 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Addition/Oxidative Rearrangement of 3‐Furfurals and 3‐Furyl Imines: New Approaches to Substituted Furans and Pyrroles.
Authors: Kelly Ann Rowley , Kerrigan Michael H. , Walsh Patrick J. 
Published: July 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Gold‐Catalyzed Double Intramolecular Alkyne Hydroalkoxylation: Synthesis of the Bisbenzanellated Spiroketal Core of Rubromycins.
Authors: Zhang Yuan , Xue Jijun , Xin Zhijun , Xie Zhixiang , Li Ying 
Published: July 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: The Reaction of α,β‐Unsaturated Sulfones with Isobenzofuran and N‐Boc‐isoindole Using Warrener′s Methodology.
Authors: Rincon Rocio , Plumet Joaquin 
Published: July 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Efficient Palladium‐Catalyzed Synthesis of 3‐Aryl‐4‐indolylmaleimides.
Authors: Pews‐Davtyan Anahit , Tillack Annegret , Ortinau Stefanie , Rolfs Arndt , Beller Matthias 
Published: July 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Ligandless Microwave‐Assisted Pd/Cu‐Catalyzed Direct Arylation of Oxazoles.
Authors: Besselievre Francois , Mahuteau‐Betzer Florence , Grierson David S. , Piguel Sandrine 
Published: July 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Alkenyl Bromides: Useful Coupling Partners for the Palladium‐Catalyzed Coupling with Heteroaromatics via a C—H Bond Activation.
Authors: Gottumukkala Aditya L. , Derridj Fazia , Djebbar Safia , Doucet Henri 
Published: July 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: A Versatile Entry to 3‐Unsubstituted 2‐Isoxazolines.
Authors: Pohjakallio Antti , Pihko Petri M. 
Published: July 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Novel Synthesis of Dihydrothiazoles from the Selenium‐Induced Cyclization of Allyl Thioureas.
Authors: Qian Hao , Lian Yanhong 
Published: July 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis of Fluoroalkyl‐δ‐lactones from Polyfluoroalkyl Iodides and 5‐Hexenoic Acids.
Authors: Fang Xiang , Ying Qi , Chen Yang , Yang Xueyan , Yang Xianjin , Wu Fanhong 
Published: July 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Improved Synthetic Approach to Tenatoprazole (VIII).
Authors: Dai Liyan , Fan Dongbo , Wang Xiaozhong , Chen Yingqi 
Published: July 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: First Example of Cu(OTf)2‐Catalyzed Synthesis of Quinoxalines from α‐Diazoketones and Aryl 1,2‐Diamines.
Authors: Yadav J. S. , Reddy B. V. Subba , Rao Y. Gopala , Narsaiah A. V. 
Published: July 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Facile Synthesis of Functionalized Oligophenothiazines via One‐Pot Bromine—Lithium Exchange—Borylation—Suzuki Coupling (BLEBS).
Authors: Franz Adam W. , Mueller Thomas J. J. 
Published: July 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis and anti‐HIV Activity Evaluation of Novel 2,4‐Disubstituted 7‐Methyl‐1,1,3‐trioxo‐2,4‐dihydro‐pyrazolo[4,5‐e][1,2]thiadiazines.
Authors: Liu Xin‐yong , Yan Ren‐zhang , Wang Yan , Zhan Peng , De Clercq Erik , Pannecouque Christophe , Witvrouw Myriam , Molina Maria Teresa , Vega Salvador 
Published: July 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Melampolides from the Leaves of Smallanthus sonchifolius and Their Inhibitory Activity of LPS‐Induced Nitric Oxide Production.
Authors: Hwang Bang Yeon , et al. et al. 
Published: July 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.