bluuebunny/crossref_metadata_2025_split huggingface dataset:
Untangling the perception of value in value-based healthcare – an interview study
Authors: Wolf Axel , Erichsen Andersson Annette , Wikström Ewa , Bååthe Fredrik 
Published: April 2024

Purpose
Value-based health care (VBHC) argues that health-care needs to re-focus to maximise value creation, defining value as the quota when dividing the outcomes important for the patient, by the cost for health care to deliver such outcomes. This study aims to explore the perception of value among different stakeholders involved in the process of implementing VBHC at a Swedish hospital to support leaders to be more efficient and effective when developing health care.

Design/methodology/approach
Participants comprised 19 clinicians and non-clinicians involved in the implementation of VBHC. Semi-structured interviews were conducted and content analysis was performed.

Findings
The clinicians described value as a dynamic concept, dependent on the patient and the clinical setting, stating that improving outcomes was more important than containing costs. The value for non-clinicians appeared more driven by the interplay between the outcome and the cost. Non-clinicians related VBHC to a strategic framework for governance or for monitoring different continuous improvement processes, while clinicians appreciated VBHC, as they perceived its introduction as an opportunity to focus more on outcomes for patients and less on cost containment.

Originality/value
There is variation in how clinicians and non-clinicians perceive the key concept of value when implementing VBHC. Clinicians focus on increasing treatment efficacy and improving medical outcomes but have a limited focus on cost and what patients consider most valuable. If the concept of value is defined primarily by clinicians’ own assumptions, there is a clear risk that the foundational premise of VBHC, to understand what outcomes patients value in their specific situation in relation to the cost to produce such outcome, will fail. Health-care leaders need to ensure that patients and the non-clinicians’ perception of value, is integrated with the clinical perception, if VBHC is to deliver on its promise.
Using augmented reality games to support sustainable development goal learning among young students: a true-experimental study
Authors: Ai-Jou Pan , Cheng Bo-Yuan , Chou Pao-Nan , Geng Ying 
Published: April 2024

PurposeWe applied a true-experimental randomized control posttest design to collect and analyze quantitative and qualitative data to compare the effects of the AR and traditional board games on students’ SDG learning achievements.Design/methodology/approachWe applied a true-experimental randomized control posttest design to collect and analyze quantitative and qualitative data to compare the effects of AR and traditional board games on students' SDG learning achievements.FindingsOur analysis of the quantitative and qualitative data revealed that the effects of AR and traditional board games on the students' cognitive outcomes differed significantly, indicating the importance of providing a situated learning environment in SDG education. Moreover, the students perceived that the incorporation of the AR game into SDG learning improved their learning effectiveness – including both cognitive and affective dimensions – thus confirming its educational value and potential in SDG learning.Originality/valueTo the best of our knowledge, this is the first study to explore the effectiveness of different learning tools (AR and traditional board games) and to evaluate the importance of providing a situated learning environment through a true-experimental randomized control posttest design.
Deciphering the role of cryptocurrencies in global remittances: a comprehensive literature review
Authors: Jegerson Devid , Mertzanis Charilaos 
Published: April 2024

PurposeIn the evolving landscape of global remittances, this study systematically explores cryptocurrency's transformative impact on remittance services through a comprehensive literature review and bibliometric analysis.Design/methodology/approachThrough meticulous PRISMA-guided analysis, the research identifies cryptocurrency technology as a pivotal force in enhancing remittance efficiency, reducing costs and broadening access contributing significantly to financial inclusion.FindingsFindings revealed that cryptocurrency technology could significantly enhance remittance services, offering improved efficiency, reduced costs and increased accessibility. This suggests a transformative potential for financial inclusion, presenting a compelling case for broader adoption and regulatory support to leverage these benefits effectively.Research limitations/implicationsBy integrating recent research, this work underlines the urgent need for broader adoption and regulatory support to leverage these benefits effectively. It offers novel insights for institutions and policymakers, highlighting the potential for technology adoption in remittances to enhance financial inclusivity.Originality/valueMore cryptocurrency studies are needed to concentrate on remittance markets. Thus, this investigation constitutes a unique addition to the field. Additional investigation in this domain presents significant possibilities for future exploration and progress.
Digitalisation as a driver of transformation for management control of small and medium-sized enterprises
Authors: Fähndrich Jochen , Pedell Burkhard 
Published: April 2024

Purpose
This study aims to analyse the influence of digitalisation on the management control function of small and medium-sized enterprises (SMEs). In particular, it aims to illuminate how digitalisation influences management control elements, organisation and roles/competencies and to identify obstacles to digitalisation of management control in SMEs and measures taken to overcome them.

Design/methodology/approach
The study is based on guideline-supported expert interviews conducted with 14 financial managers from SMEs in Germany, Austria and Switzerland.

Findings
This study reveals the influence of digitalisation on management control elements, organisation, and roles/competencies. The automation and standardisation of management control processes result in new elements for management control, such as strategic support for management. In addition, the increased availability and transparency of data enable the use of instruments within a company that allow for quick analyses of the company's development. Digitalisation leads to the integration of management control into the corporate network and, thus, a change in the organisation of management control. It also triggers the expansion of management control competencies, especially IT competencies. A shortage of internal digitalisation resources, unclear corporate roadmaps, and a lack of managerial experience loom as central challenges for digitalising the management control function. Measures derived from the interviews can help SMEs overcome the obstacles to the digitalisation of management control.

Originality/value
This research is the first interview-based study of the impact of digitalisation on management control in SMEs, potential obstacles to that digitalisation, and measures to overcome those obstacles. Thus, it contributes to the emerging debate on factors that may explain why SMEs lag in terms of the digitalisation of their internal processes.
Digitalization and digital transformation in the tourism industry: a bibliometric review and research agenda
Authors: Bekele Henok , Raj Sahil 
Published: April 2024

Purpose
In recent decades, a significant number of research contributions have been made to the intersection of digital technologies and the tourism industry. However, a thorough examination of digitalization and digital transformation in the tourism industry has not been given sufficient consideration. This study aims to provide a bibliometric review of digitalization and digital transformation research in the tourism industry and devise future research agendas to advance the research field.

Design/methodology/approach
This study uses the Scientific Procedures and Rationales for Systematic Literature Reviews (SPAR-4-SLR) protocol and a bibliometric analysis to examine the research progress and scientifically map the research domain of digitalization and digital transformation in the tourism industry from 2002 to 2023 using bibliographic data retrieved from the Scopus and Web of Science.

Findings
This study presents the trends in publications and citations within the digitalization and digital transformation research domain in tourism. The findings also provide insights into the four primary clusters of the research field: digital innovation, smart tourism ecosystem, eTourism and smart destination experience. To further augment the application of digital transformation, this study offers several recommendations for future research on digitalization and digital transformation of the tourism industry.

Practical implications
This study provides valuable implications to researchers, managers and policymakers seeking to understand the current state and future research directions in tourism’s digitalization and digital transformation research field.

Originality/value
This study advances the research field of digitalization and digital transformation in the tourism industry by thoroughly examining the primary research clusters in the research corpus of the past two decades. Furthermore, it guides future research, thereby setting the stage for further progress in this domain.
Elevating the significance of legume intake: A novel strategy to counter aging‐related mitochondrial dysfunction and physical decline
Authors: Zheng Qingwei , Wang Feijie , Nie Chenzhipeng , Zhang Kuiliang , Sun Yujie , AL‐Ansi Waleed , Wu Qiming , Wang Li , Du Jun , Li Yan 
Published: April 2024

AbstractMitochondrial dysfunction increasingly becomes a target for promoting healthy aging and longevity. The dysfunction of mitochondria with age ultimately leads to a decline in physical functions. Among them, biogenesis dysfunction and the imbalances in the metabolism of reactive oxygen species and mitochondria as signaling organelles in the aging process have aroused our attention. Dietary intervention in mitochondrial dysfunction and physical decline during aging processes is essential, and greater attention should be directed toward healthful legume intake. Legumes are constantly under investigation for their nutritional and bioactive properties, and their consumption may yield antiaging and mitochondria‐protecting benefits. This review summarizes mitochondrial dysfunction with age, discusses the benefits of legumes on mitochondrial function, and introduces the potential role of legumes in managing aging‐related physical decline. Additionally, it reveals the benefits of legume intake for the elderly and offers a viable approach to developing legume‐based functional food.
‘No safe haven’: Why theGATT‘regional exception’ does not apply to technical barriers to trade
Authors: Nuzzo Silvia 
Published: April 2024

AbstractDuring the last two decades, Preferential Trade Agreements (PTAs) have increased in quantity and broadened in scope. Far from merely reducing tariffs, they now set out a detailed discipline also on behind‐the‐border measures. Due to their trade‐restrictive potential, technical barriers to trade (TBTs) are now systematically regulated in PTAs. Since PTAs discriminate by definition, it is pivotal to understand whether their regulation of TBTs may be reconciled with the multilateral non‐discrimination obligation. Against this backdrop, this article aims to assess whether WTO‐incompatible TBT provisions in PTAs may benefit from the GATT 1994 ‘Regional Exception’, that is, Article XXIV. I will argue that, by virtue of thelex specialisprinciple, Article XXIV may not shield violations of the TBT Agreement. The impact of this study is two‐fold. First, it shows that Members of the World Trade Organization (WTO) must respect the Most‐Favoured Nation (MFN) clause when integrating their domestic policies. Second, using TBTs as a case study, it proposes some crucial adjustments to WTO case law, that should be considered also when deciding on the interplay between the GATT 1994 and WTO Agreements other than the TBT Agreement.
The social status of women in China: Analysis based on age, period, and cohort effects
Authors: Wang Dian , Lyu Xiaokang , Chen Lijun 
Published: April 2024

AbstractThe present study examined the social status of women in China by reviewing the levels and trends of objective and subjective socioeconomic status and gender role attitudes. We employed a hierarchical age–period–cohort analysis and used repeated cross‐sectional data from the 2010 to 2021 Chinese General Social Survey (N = 52,927), a nationwide probability survey. The study found that for both males and females, differences in age effects were more pronounced than period and cohort effects. Specifically, there were no significant gender differences in levels of education. However, women start at a lower level of occupational prestige and income than men. Particularly in late adulthood, the rate of decline in income is significantly faster for women than for adult men. Chinese women's gender role attitudes interact with their objective socioeconomic status. Subjectively, China's awareness and recognition of gender equality and women's rights and interests are increasing, but objective gender inequality still exists, and there are many challenges to be addressed.
Evaluation of critical parameters in the hollow‐fibre system for tuberculosis: A case study of moxifloxacin
Authors: Aguilar‐Ayala Diana A. , Sanz‐García Fernando , Rabodoarivelo Marie Sylvianne , Susanto Budi O. , Bailo Rebeca , Eveque‐Mourroux Maxime R. , Willand Nicolas , Simonsson Ulrika S. H. , Ramón‐García Santiago , Lucía Ainhoa ,   the ERA4TB consortium
Published: April 2024

AimsThe hollow‐fibre system for tuberculosis (HFS‐TB) is a preclinical model qualified by the European Medicines Agency to underpin the anti‐TB drug development process. It can mimic in vivo pharmacokinetic (PK)–pharmacodynamic (PD) attributes of selected antimicrobials, which could feed into in silico models to inform the design of clinical trials. However, historical data and published protocols are insufficient and omit key information to allow experiments to be reproducible. Therefore, in this work, we aim to optimize and standardize various HFS‐TB operational procedures.MethodsFirst, we characterized bacterial growth dynamics with different types of hollow‐fibre cartridges, Mycobacterium tuberculosis strains and media. Second, we mimicked a moxifloxacin PK profile within hollow‐fibre cartridges, in order to check drug–fibres compatibility. Lastly, we mimicked the moxifloxacin total plasma PK profile in human after once daily oral dose of 400 mg to assess PK–PD after different sampling methods, strains, cartridge size and bacterial adaptation periods before drug infusion into the system.ResultsWe found that final bacterial load inside the HFS‐TB was contingent on the studied variables. Besides, we demonstrated that drug–fibres compatibility tests are critical preliminary HFS‐TB assays, which need to be properly reported. Lastly, we uncovered that the sampling method and bacterial adaptation period before drug infusion significantly impact actual experimental conclusions.ConclusionOur data contribute to the necessary standardization of HFS‐TB experiments, draw attention to multiple aspects of this preclinical model that should be considered when reporting novel results and warn about critical parameters in the HFS‐TB currently overlooked.
The micro‐foundations of employment systems: An empirical case study of Britain and France
Authors: Amossé Thomas , Bryson Alex , Forth John , Petit Héloïse 
Published: April 2024

AbstractBuilding on existing studies of national employment systems, we undertake a comparative analysis of the micro‐foundations of employment relations in Britain and France. Our analysis utilizes harmonized, linked employer‐employee survey data for the two countries and takes a multi‐dimensional approach in which the national level remains meaningful but within‐country variance is also emphasized. Our analysis contrasts the British model characterized by variability and heterogeneity with a French model characterized by stability and uniformity. We discuss ways in which these systems are shaped by differences in employer and employee networks, the financial and organizational links between firms and macro‐institutions.
Three new corrections for standardized person‐fit statistics for tests with polytomous items
Authors: Gorney Kylie 
Published: April 2024

AbstractRecent years have seen a growing interest in the development of person‐fit statistics for tests with polytomous items. Some of the most popular person‐fit statistics for such tests belong to the class of standardized person‐fit statistics, , that is assumed to have a standard normal null distribution. However, this distribution only holds when (a) the true ability parameter is known and (b) an infinite number of items are available. In practice, both conditions are violated, and the quality of person‐fit results is expected to deteriorate. In this paper, we propose three new corrections for that simultaneously account for the use of an estimated ability parameter and the use of a finite number of items. The three new corrections are direct extensions of those that were developed by Gorney et al. (Psychometrika, 2024, https://doi.org/10.1007/s11336‐024‐09960‐x) for tests with only dichotomous items. Our simulation study reveals that the three new corrections tend to outperform not only the original statistic but also an existing correction for proposed by Sinharay (Psychometrika, 2016, 81, 992). Therefore, the new corrections appear to be promising tools for assessing person fit in tests with polytomous items.
Postnatal hypofunction of N‐methyl‐D‐aspartate receptors alters perforant path synaptic plasticity and filtering and impairs dentate gyrus‐mediated spatial discrimination
Authors: Márquez Luis A. , López Rubalcava Carolina , Galván Emilio J. 
Published: April 2024

Background and PurposeTransient hypofunction of the NMDA receptor represents a convergence point for the onset and further development of psychiatric disorders, including schizophrenia. Although the cumulative evidence indicates dysregulation of the hippocampal formation in schizophrenia, the integrity of the synaptic transmission and plasticity conveyed by the somatosensorial inputs to the dentate gyrus, the perforant pathway synapses, have barely been explored in this pathological condition.Experimental ApproachWe identified a series of synaptic alterations of the lateral and medial perforant paths in animals postnatally treated with the NMDA antagonist MK‐801. This dysregulation suggests decreased cognitive performance, for which the dentate gyrus is critical.Key ResultsWe identified alterations in the synaptic properties of the lateral and medial perforant paths to the dentate gyrus synapses in slices from MK‐801‐treated animals. Altered glutamate release and decreased synaptic strength precede an impairment in the induction and expression of long‐term potentiation (LTP) and CB1 receptor‐mediated long‐term depression (LTD). Remarkably, by inhibiting the degradation of 2‐arachidonoylglycerol (2‐AG), an endogenous ligand of the CB1 receptor, we restored the LTD in animals treated with MK‐801. Additionally, we showed for the first time, that spatial discrimination, a cognitive task that requires dentate gyrus integrity, is impaired in animals exposed to transient hypofunction of NMDA receptors.Conclusion and ImplicationsDysregulation of glutamatergic transmission and synaptic plasticity from the entorhinal cortex to the dentate gyrus has been demonstrated, which may explain the cellular dysregulations underlying the altered cognitive processing in the dentate gyrus associated with schizophrenia.
Burden of impaired sleep and its improvement through topical treatment in psoriasis and atopic dermatitis
Authors: Mann Caroline , Dreher Matthias , Rothschmidt Jan‐Niklas , Staubach Petra 
Published: April 2024

SummaryIntroductionPatients with chronic inflammatory skin diseases often suffer from sleep disturbances. However, objective data on sleep architecture, especially to evaluate potential overall influences under therapy, are lacking.Patients and methodsPilot study on sleep quality changes including psoriasis and atopic dermatitis patients before and 2 weeks after intensive topical treatment. In addition to disease activity rating, patient‐rated outcomes for itch severity and sleep quality and polygraphy was performed before and after topical therapy.Results14 psoriasis, eleven atopic dermatitis patients (10 female, 15 male) with a mean age of 49 years were included. Disease activity scores (EASI and PASI) were significantly reduced with topical therapy after 2 weeks (p < 0.001). Pruritus intensity (NRS) showed a significant influence on deep sleep, which resolved after therapy. Insomnia severity significantly decreased (r > 0.50, p < 0.05) and daytime sleepiness showed a significant reduction in 40% of patients. N3 (deep sleep) and REM sleep significantly improved, showing a strong effect (r > 0.50). The apnea‐hypopnea index decreased in one of four patients independent of the individual BMI.ConclusionsThrough polygraphy, we demonstrated impaired sleep patterns in psoriasis and atopic dermatitis patients with itch as a relevant factor and beyond that, rapid sleep improvement under 2 weeks of topical treatment.
Development of microsatellite markers for the endangered butterfly Luehdorfia japonica Leech, 1889 (Lepidoptera: Papilionidae)
Authors: Ueda Shouhei , Nakasuji Chiaki , Nakahama Naoyuki , Hirai Norio , Ishii Minoru 
Published: April 2024

ABSTRACTThe endangered butterfly species Luehdorfia japonica Leech, 1889 (Lepidoptera, Papilionidae) is endemic to the central and western parts of Honshu, Japan. This species inhabits deciduous forests and coppices, but areas of optimal habitats are decreasing due to the development of land and the abandonment of regular coppice management. We developed 17 microsatellite loci for L. japonica based on de novo genome sequence data and found that 16 of these loci exhibited polymorphisms in 34 individuals of L. japonica. In addition, polymorphisms of 15 of these microsatellite loci were observed in two individuals of L. puziloi. The number of alleles and the expected heterozygosity per locus in L. japonica were 2–11 and 0.11–0.83, respectively. A principal coordinate analysis based on this genetic information revealed genetic differentiation both within and among geographic populations of L. japonica. Thus, these microsatellite loci could potentially be useful for future conservation genetic studies, including monitoring the genetic diversity and population structure of this endangered butterfly species.
Venture capital and stock price informativeness: Evidence from China
Authors: Feng Huiqun , Wang Qingwei , Xiao Jason Zezhong 
Published: April 2024

AbstractThis study shows that, unlike the positive role played by other institutional investors documented in the literature, venture capital (VC) in pursuit of short‐term gains through exit strategies reduces the stock price informativeness of portfolio companies, especially when VC is associated with a higher level of the ability (longer‐term VC directors, large VC syndicate), incentive (private VC sponsors), and willingness (less reputable VCs) to manipulate information. Furthermore, internal and external monitoring helps mitigate the negative impact of VC on stock price informativeness. Finally, earnings management and reduced information disclosure mediate the relationship between VC involvement and stock price informativeness.