bluuebunny/crossref_metadata_2025_split huggingface dataset:
Hyaluronic acid–polyethyleneimine conjugate for target specific intracellular delivery of siRNA
Authors: Jiang Ge , Park Kitae , Kim Jiseok , Kim Ki Su , Oh Eun Ju , Kang Hyungu , Han Su‐Eun , Oh Yu‐Kyoung , Park Tae Gwan , Kwang Hahn Sei 
Published: March 2008

AbstractA novel target specific small interfering RNA (siRNA) delivery system was successfully developed using polyethyleneimine (PEI)–hyaluronic acid (HA) conjugate. Anti‐PGL3‐Luc siRNA was used as a model system suppressing the PGL3‐Luc gene expression. The siRNA/PEI‐HA complex with an average size of ca. 21 nm appeared to be formed by electrostatic interaction between the negatively charged siRNA and the positively charged PEI of PEI‐HA conjugate. The cytotoxicity of siRNA/PEI‐HA complex to B16F1 cells was lower than that of siRNA/PEI complex according to the MTT assay. When B16F1 and HEK‐293 cells were treated with fluorescein isothiocyanate (FITC) labeled siRNA/PEI‐HA complex, B16F1 cells, with a lymphatic vessel endothelial hyaluronan receptor‐1 (LYVE‐1), showed higher green fluorescent intensity than HEK‐293 cells because of the HA receptor mediated endocytosis of the complex. Accordingly, the PGL3‐Luc gene silencing of anti‐PGL3‐Luc siRNA/PEI‐HA complex was more efficient in B16F1 cells than in HEK‐293 cells. In addition, the inhibited PGL3‐Luc gene silencing effect in the presence of free HA in the transfection medium revealed that siRNA/HA‐PEI complex was selectively taken up to B16F1 cells via HA receptor mediated endocytosis. All these results demonstrated that the intracellular delivery of anti‐PGL3‐Luc siRNA/PEI‐HA complex could be facilitated by the HA receptor mediated endocytosis. © 2008 Wiley Periodicals, Inc. Biopolymers 89: 635–642, 2008.This article was originally published online as an accepted preprint. The “Published Online” date corresponds to the preprint version. You can request a copy of the preprint by emailing the Biopolymers editorial office at biopolymers@wiley.com
Intestinal regeneration by a novel surgical procedure
Authors: Jwo S-C , Chiu J-H , Ng K-K , Chen H-Y 
Published: March 2008

Abstract

Background
Treatment of short bowel syndrome is problematical. Small bowel tissue engineering has achieved modest results in animal studies. The aim of this study was to investigate intestinal regeneration in a novel surgical model.

Methods
Roux-en-Y bypass procedures were performed on 40 Wistar rats weighing 250–350 g. Animals were killed at 1, 2, 3, 4, 8, 12 and 24 weeks after implantation with a 3-cm silicone tube. The spatio temporal relationship of intestinal regeneration was analysed using three-dimensional multislice computed tomography, and examination of sequential morphological changes on gross or histological findings and measurement of missing intestinal tissue (growth defects).

Results
Progressive intestinal regeneration on a silicone tube was identifiable in 35 animals. Most adhesions were initially localized on the tube but spread to a distal site 4 weeks after implantation. Growth defects decreased with time, with a marked reduction in the first 4 weeks and a gradual reduction to week 24 after implantation. Luminal patency shown radiologically as well as sequential histological findings, such as mucosal lining, matrix remodelling and muscular regeneration, suggested that regeneration of intestinal tissue took place, not merely scar contraction.

Conclusion
Non-invasive as well as histomorphological assessment followed intestinal regeneration over time in this model, which provides scope for further studies.
An efficient dynamic point algorithm for line‐based collision detection in real time virtual environments involving haptics
Authors: Maciel Anderson , De Suvranu 
Published: March 2008

AbstractIn real time computer graphics, “interactivity” is limited to a display rate of 30 frames per second. However, in multimodal virtual environments involving haptic interactions, a much higher update rate of about 1 kHz is necessary to ensure continuous interactions and smooth transitions. The simplest and most efficient interaction paradigm in such environments is to represent the haptic cursor as a point. However, in many situations, such as those in the development of real time medical simulations involving the interactions of long slender surgical tools with soft deformable organs, such a paradigm is nonrealistic and at least a line‐based interaction is desirable. While such paradigms exist, the main impediment to their widespread use is the associated computational complexity. In this paper, we introduce, for the first time, an efficient algorithm for computing the interaction of a line‐shaped haptic cursor and polygonal surface models which has a near constant complexity. The algorithm relies on space‐time coherence, topological information, and the properties of lines in 3D space to maintain proximity information between a line segment and triangle meshes. For interaction with convex objects, the line is represented by its end points and a dynamic point, which is the closest point on the line to any potentially colliding triangle. To deal with multiple contacts and non‐convexities, the line is decomposed into segments and a dynamic point is used for each segment. The algorithm may be used to compute collision detection and response with rigid as well as deformable objects with no performance penalty. Realistic examples are presented to demonstrate the effectiveness of our approach. Copyright © 2008 John Wiley & Sons, Ltd.
IR Spectroscopic Properties of H(MeOH)n+ Clusters in the Liquid Phase: Evidence for a Proton Wire
Authors: Stoyanov Evgenii S. , Stoyanova Irina V. , Reed Christopher A. 
Published: March 2008

AbstractThe long‐standing problem of understanding the nature of the “excess proton” in acidified water is simplified by studying the proton in methanol. The 3D network of hydrogen bonds in H(aq)+ is reduced to a 1D problem. Infrared spectroscopic characterization of linear chain methanol proton solvates in H(CH3OH)n+ for n=2–8 provides insight into some of the puzzling IR spectral features associated with O‐H‐O vibrations. These include the virtual disappearance of otherwise strong bands from H‐bonded methanol molecules adjacent to symmetrical O‐H+‐O groups. The data indicate that a chain of up to four OH⋅⋅⋅O bonds either side of this group can act as an electrical wire to separate positive charge. This suggests a refinement of the Grotthuss proton‐hopping mechanism for explaining the anomalously high mobility of H+ in H‐bonded media.
ChemInform Abstract: Structural Phase Transition of Gd3RuO7.
Authors: Ishizawa Nobuo , Tateishi Kenji , Kondo Saki , Suwa Tsuyoshi 
Published: March 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Experimental Investigation and Thermodynamic Description of the In—Sb—Sn Ternary System.
Authors: Manasijevic Dragan , Vrest'al Jan , Minic Dusko , Kroupa Ales , Zivkovic Dragana , Zivkovic Zivan 
Published: March 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Self‐Templated Synthesis of Nanoporous CdS Nanostructures for Highly Efficient Photocatalytic Hydrogen Production under Visible Light.
Authors: Bao Ningzhong , Shen Liming , Takata Tsuyoshi , Domen Kazunari 
Published: March 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Facile Synthesis of Troilite.
Authors: Pedoussaut Nathalie M. , Lind Cora 
Published: March 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Construction of Three Contiguous Tertiary Stereocenters from Aziridines in One Step.
Authors: Blyumin Evgeniy V. , Gallon Helen J. , Yudin Andrei K. 
Published: March 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: N‐Heterocyclic Carbene‐Catalyzed Redox Amidations of α‐Functionalized Aldehydes with Amines.
Authors: Bode Jeffrey W. , Sohn Stephanie S. 
Published: March 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Rh‐Catalyzed Highly Enantioselective Formation of Functionalized Cyclopentanes and Cyclopentanones
Authors: Liu Fei , Liu Qiang , He Minsheng , Zhang Xumu , Lei Aiwen 
Published: March 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Functional Group‐Selective Poisoning of Molecular Catalysts: A Ruthenium Cluster‐Catalyzed Highly Amide‐Selective Silane Reduction that Does Not Affect Ketones or Esters.
Authors: Sasakuma Hidehiro , Motoyama Yukihiro , Nagashima Hideo 
Published: March 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Catalytic Oxidation of Hydrazo Derivatives Promoted by a TiCl3/HBr System.
Authors: Drug Eyal , Gozin Michael 
Published: March 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Ruthenium Janus—Head Complexes with a Triazolediylidene Ligand. Structural Features and Catalytic Applications.
Authors: Viciano Monica , Sanau Mercedes , Peris Eduardo 
Published: March 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: One‐Step Synthesis of SBA‐15 Containing Tungsten Oxide Nanoclusters: A Chemoselective Catalyst for Oxidation of Sulfides to Sulfoxides under Ambient Conditions.
Authors: Bordoloi Ankur , Vinu Ajayan , Halligudi S. B. 
Published: March 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Solvent Effect on Sulfur Ylide Mediated Epoxidation Reaction.
Authors: Lee Hee‐Yoon , Bae Imhyuck , Min Kyung‐Hyun 
Published: March 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Oxidation of 3,4‐Diaryl‐2,5‐dihydrothiophenes to 3,4‐Diarylthiophenes Using CuBr2: Simple and Efficient Preparation of 3,4‐Diarylthiophenes.
Authors: Dang Yizhe , Chen Yi 
Published: March 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Acid‐Catalyzed Rearrangement of Fused Alkylideneoxetanols.
Authors: Hickford Paul J. , Baker James R. , Bruce Ian , Booker‐Milburn Kevin I. 
Published: March 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: An Efficient Synthesis of 2‐Diazo‐2‐(trimethylsilyl)ethanols and Their Application to Pyrazole Synthesis.
Authors: Hari Yoshiyuki , Tsuchida Susumu , Sone Ryosuke , Aoyama Toyohiko 
Published: March 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Microwave‐Assisted Synthesis of N‐2‐Benzyl‐3‐(4‐ethoxycarbonylphenyl)indazole Derivatives.
Authors: Chen Hua‐Sin , Huang Li‐Jiau , Wong Fung Fuh , Lee Fang‐Yu , Teng Che‐Ming , Kuo Sheng‐Chu 
Published: March 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Chemo‐, Regio‐ and Stereoselective Preparation of Silyl Enol Ethers from Thiol Esters and Bis(iodozincio)alkane.
Authors: Ooguri Akihiro , Ikeda Zenichi , Matsubara Seijiro 
Published: March 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis of Novel Ladder Bis‐Silicon‐Bridged p‐Terphenyls.
Authors: Li Liangchun , Xiang Junfeng , Xu Caihong 
Published: March 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Diastereoselective Synthesis of Glutamate‐Appended Oxolane Rings: Synthesis of (S)‐(+)‐Lycoperdic Acid (I).
Authors: Cohen Jamie L. , Chamberlin A. Richard 
Published: March 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Stereoselective Synthesis of 2‐Deoxy‐furanosides from 2,3‐Anhydro‐furanosyl Thioglycosides.
Authors: Hou Dianjie , Lowary Todd L. 
Published: March 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: A New, Powerful Glycosylation Method: Activation of Thioglycosides with Dimethyl Disulfide—Triflic Anhydride.
Authors: Tatai Janos , Fuegedi Peter 
Published: March 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Total Synthesis of the Cyclopeptide Alkaloid Abyssenine A (I). Application of Inter‐ and Intramolecular Copper‐Mediated Coupling Reactions in Organic Synthesis.
Authors: Toumi Mathieu , Couty Francois , Evano Gwilherm 
Published: March 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Structure—Activity Relationships of Neoechinulin A Analogues with Cytoprotection Against Peroxynitrite‐Induced PC12 Cell Death.
Authors: Arai Takao , et al. et al. 
Published: March 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: First Total Synthesis and Absolute Configuration of the Styryl Lactone Gonioheptolide A.
Authors: Gupta Shuchi , Rajagopalan Murali , Alhamadsheh Mamoun M. , Tillekeratne L. M. Viranga , Hudson Richard A. 
Published: March 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: An Enantioselective Total Synthesis of (+)‐Aigialospirol.
Authors: Figueroa Ruth , Hsung Richard P. , Guevarra Christle C. 
Published: March 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis of (+)‐Vinblastine and Its Analogues.
Authors: Miyazaki Tohru , Yokoshima Satoshi , Simizu Siro , Osada Hiroyuki , Tokuyama Hidetoshi , Fukuyama Tohru 
Published: March 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Stereoselective Synthesis of Methyl 7‐Dihydro‐trioxacarcinoside B.
Authors: Koenig Christian M. , Harms Klaus , Koert Ulrich 
Published: March 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: γ‐Substituted Bis(pivaloyloxymethyl)ester Analogues of Fosmidomycin and FR900098.
Authors: Kurz Thomas , Behrendt Christoph , Pein Miriam , Kaula Uwe , Bergmann Baerbel , Walter Rolf D. 
Published: March 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Aromaticity and Antiaromaticity in Transition‐Metal Systems
Authors: Zubarev Dmitry Yu. , Averkiev Boris B. , Zhai Hua‐Jin , Wang Lai‐Sheng , Boldyrev Alexander I. 
Published: March 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Ordered Mesoporous Materials at the Beginning of the Third Millennium: New Strategies to Create Hybrid and Non‐Siliceous Variants
Authors: Van der Voort Pascal , Vercaemst Carl , Schaubroeck David , Verpoort Francis 
Published: March 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Chalcogen—Phosphorus (And Heavier Congeners) Chemistry
Authors: Davies Rob 
Published: March 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: The Compounds Between Si, Ge and Sn and Chalcogens (S, Se, and Te) Having Both a Single Bond and a Double Bond (Heavy Ketones)
Authors: Takeda Nobuhiro , Tokitoh Norihiro , Okazaki Renji 
Published: March 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Trifluoromethylboranes and ‐borates: New Synthetic Strategies and Applications
Authors: Finze Maik , Bernhardt Eduard , Willner Helge 
Published: March 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Total Synthesis of Azadirachtin — Finally Completed After 22 Years.
Authors: Jauch Johann 
Published: March 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.