bluuebunny/crossref_metadata_2025_split huggingface dataset:
A spectropolarimetric study of the radio galaxy Pictor A using MeerKAT
Authors: Andati Lexy A L , Baidoo Lerato M , Ramaila Athanaseus J T , Smirnov Oleg M , Makhathini Sphesihle , Perley Richard A 
Published: February 2024

ABSTRACT
We present the results of a polarimetric study from our new high-sensitivity L-band (0.8–1.7 GHz) observation of Pictor A using the MeerKAT radio telescope. We confirm the presence of the radio jet extending from the nucleus to the western hotspot of this source. Additionally, we show the radio emission expected to coincide with previously observed X-ray emission in the radio lobes, confirming that the emission mechanism is of inverse Compton origin, as suggested by a previous study. Our spectropolarimetric analysis using the rotation measure synthesis technique reveals a relatively uniform mean rotation measure distribution across the lobes of Pictor A, with most lines of sight exhibiting single-peaked Faraday spectra. However, a number of the lines of sight exhibit single peaked spectra with a wide base or multiple peaks, suggesting the presence of multiple Faraday components or a Faraday thick structure along Pictor A’s lines of sight. We also confirm the asymmetry in rotation measure variability and depolarization between the two lobes of this source, as reported in a previous study.
Supernova rates and luminosity functions from ASAS-SN I: 2014–2017 Type Ia SNe and their subtypes
Authors: Desai D D , Kochanek C S , Shappee B J , Jayasinghe T , Stanek K Z , Holoien T W -S , Thompson T A , Ashall C , Beacom J F , Do A , Dong Subo , Prieto J L 
Published: February 2024

ABSTRACT
We present the volumetric rates and luminosity functions (LFs) of Type Ia supernovae (SNe Ia) from the V-band All-Sky Automated Survey for Supernovae (ASAS-SN) catalogues spanning discovery dates from UTC 2014 January 26 to UTC 2017 December 29. Our standard sample consists of 404 SNe Ia with $m_{\mathrm{{\it V},peak}} \lt 17\, \mathrm{mag}$ and Galactic latitude |b| &gt; 15°. Our results are both statistically more precise and systematically more robust than previous studies due to the large sample size and high spectroscopic completeness. We make completeness corrections based on both the apparent and absolute magnitudes by simulating the detection of SNe Ia in ASAS-SN light curves. We find a total volumetric rate for all subtypes of $R_{\mathrm{tot}} = 2.28^{+0.20}_{-0.20} \times 10^{4}\, \mathrm{yr}^{-1}\, \mathrm{Gpc}^{-3}\, h^{3}_{70}$ for $M_{\mathrm{{\it V},peak}} \lt -16.5\, \mathrm{mag}$ ($R_{\mathrm{tot}} = 1.91^{+0.12}_{-0.12} \times 10^{4}\, \mathrm{yr}^{-1}\, \mathrm{Gpc}^{-3}\, h^{3}_{70}$ for $M_{\mathrm{{\it V},peak}} \lt -17.5\, \mathrm{mag}$) at the median redshift of our sample, zmed = 0.024. This is in agreement (1σ) with the local volumetric rates found by previous studies. We also compile LFs for the entire sample as well as for subtypes of SNe Ia for the first time. The major subtypes with more than one SN include Ia-91bg, Ia-91T, Ia-CSM, and Ia-03fg with total rates of $R_{\mathrm{Ia-91bg}} = 1.4^{+0.5}_{-0.5} \times 10^{3}\, \mathrm{yr}^{-1}\, \mathrm{Gpc}^{-3}\, h^{3}_{70}$, $R_{\mathrm{Ia-91T}} = 8.5^{+1.6}_{-1.7} \times 10^{2}\, \mathrm{yr}^{-1}\, \mathrm{Gpc}^{-3}\, h^{3}_{70}$, $R_{\mathrm{Ia-CSM}} = 10^{+7}_{-7}\, \mathrm{yr}^{-1}\, \mathrm{Gpc}^{-3}\, h^{3}_{70}$, and $R_{\mathrm{Ia-03fg}} = 30^{+20}_{-20}\, \mathrm{yr}^{-1}\, \mathrm{Gpc}^{-3}\, h^{3}_{70}$, respectively. We estimate a mean host extinction of $E(V-r) \approx 0.2\, \mathrm{mag}$ based on the shift between our V band and the Zwicky Transient Facility r-band LFs.
Flows of Local Sheet dwarfs in relation to the Council of Giants
Authors: Seaton Lucas M , McCall Marshall L , McCall Neil T 
Published: February 2024

ABSTRACT
The kinematics of isolated dwarf galaxies in the Local Sheet have been studied to ascertain how the Council of Giants has affected flows. Peculiar velocities parallel to the Sheet in the frame of reference of the Council ascend steeply from negative to positive values on the near side of the Council at a heliocentric radius of $2.4 \pm 0.2 \, \rm Mpc$ . They descend to pre-ponderantly negative values at a radius of $3.9^{+0.4}_{-0.5} \, \rm Mpc$, which is near the middle of the Council realm. Such behaviour is evidence for a flow field set up by the combined gravitational effects of the Local Group and Council, the ascending node being where their gravitational forces balance. Receding dwarfs on the near side of the Council are pre-dominantly located in the direction of M94, although this may be a manifestation of the limitations of sampling. If M94 were entirely responsible for the placement of the ascending node, then the galaxy’s total mass relative to the Local Group would have to be $0.8^{+0.4}_{-0.3}$, the same as indicated by the orbits of satellite galaxies. Rather, if the placement of the ascending node were set by matter distributed evenly in azimuth at the Council’s radius, then the required total mass relative to the Local Group would have to be $4^{+3}_{-2}$, which is 30 per cent to 40 per cent lower than implied by satellite motions but still consistent within errors. The mere existence of the ascending node confirms that the Council of Giants limits the gravitational reach of the Local Group.
Peeling back the layers of extinction of dusty galaxies in the era of JWST: modelling joint NIRSpec + MIRI spectra at rest-frame 1.5–28 μm
Authors: Donnan F R , García-Bernete I , Rigopoulou D , Pereira-Santaella M , Roche P F , Alonso-Herrero A 
Published: February 2024

ABSTRACT
We present an analysis of the combined NIRSpec and MIRI spectra of dusty galaxies between 1.5 and 28 $\mu$m rest-frame by implementing a differential extinction model, where the strength of extinction varies across the spectrum as different layers of the obscuring dust are probed. Our model is able to recover a 2D distribution of dust temperature and extinction, which allows inference of the physical nature of the dust in these environments. We show that differential extinction is necessary to reproduce the spectra of four highly obscured Luminous Infrared Galaxies observed with NIRSpec IFU and MIRI MRS, where simple screen or uniformly mixed dust distributions fail to fit the data. We additionally compare the extinction of H ii regions in these galaxies via hydrogen recombination lines, the extinction of molecular gas via the H2 lines, polycyclic aromatic hydrocarbons via the 12.7/11.3 PAH ratio and the stellar continuum. We find that the molecular gas is deeply buried with the H ii regions in star-forming regions, with a similar extinction to the hottest dust components. However, we find the cooler dust to be less obscured, at a similar extinction to the stellar continuum and PAHs. The nuclei show a complex dust distribution with VV114 NE, NGC 3256 S, and IIZw96 SW, showing a deeply buried continuum source relative to the molecular gas/H ii regions. Additionally, NGC 3256 S, NGC 7469, and VV114 SW show an isolated hot dust component, indicative of AGN heating, where NGC 3256 S and NGC 7469 are previously known as AGN.
How does the radio enhancement of broad absorption line quasars relate to colour and accretion rate?
Authors: Petley James W , Morabito Leah K , Rankine Amy L , Richards Gordon T , Thomas Nicole L , Alexander David M , Fawcett Victoria A , Calistro Rivera Gabriela , Prandoni Isabella , Best Philip N , Kolwa Sthabile 
Published: February 2024

ABSTRACT
The origin of radio emission in different populations of radio-quiet quasars is relatively unknown, but recent work has uncovered various drivers of increased radio-detection fraction. In this work, we pull together three known factors: optical colour (g − i), C iv distance (a proxy for L/LEdd), and whether or not the quasar contains broad absorption lines (BALQSOs) which signify an outflow. We use SDSS (Sloan Digital Sky Survey) DR14 spectra along with the LOFAR Two Metre Sky Survey Data Release 2 and find that each of these properties have an independent effect. BALQSOs are marginally more likely to be radio-detected than non-BALQSOs at similar colours and L/LEdd, moderate reddening significantly increases the radio-detection fraction and the radio detection increases with L/LEdd above a threshold for all populations. We test a widely used simple model for radio wind shock emission and calculate energetic efficiencies that would be required to reproduce the observed radio properties. We discuss interpretations of these results concerning radio-quiet quasars more generally. We suggest that radio emission in BALQSOs is connected to a different physical origin than the general quasar population since they show different radio properties independent of colour and C iv distance.
CSB and SMARCAL1 compete for RPA32 at stalled forks and differentially control the fate of stalled forks in BRCA2-deficient cells
Authors: Batenburg Nicole L , Sowa Dana J , Walker John R , Andres Sara N , Zhu Xu-Dong 
Published: February 2024

AbstractCSB (Cockayne syndrome group B) and SMARCAL1 (SWI/SNF-related, matrix-associated, actin-dependent, regulator of chromatin, subfamily A-like 1) are DNA translocases that belong to the SNF2 helicase family. They both are enriched at stalled replication forks. While SMARCAL1 is recruited by RPA32 to stalled forks, little is known about whether RPA32 also regulates CSB’s association with stalled forks. Here, we report that CSB directly interacts with RPA, at least in part via a RPA32C-interacting motif within the N-terminal region of CSB. Modeling of the CSB-RPA32C interaction suggests that CSB binds the RPA32C surface previously shown to be important for binding of UNG2 and SMARCAL1. We show that this interaction is necessary for promoting fork slowing and fork degradation in BRCA2-deficient cells but dispensable for mediating restart of stalled forks. CSB competes with SMARCAL1 for RPA32 at stalled forks and acts non-redundantly with SMARCAL1 to restrain fork progression in response to mild replication stress. In contrast to CSB stimulated restart of stalled forks, SMARCAL1 inhibits restart of stalled forks in BRCA2-deficient cells, likely by suppressing BIR-mediated repair of collapsed forks. Loss of CSB leads to re-sensitization of SMARCAL1-depleted BRCA2-deficient cells to chemodrugs, underscoring a role of CSB in targeted cancer therapy.
A circular RNA-gawky-chromatin regulatory axis modulates stress-induced transcription
Authors: Su Rui , Zhou Min , Lin Jiamei , Shan Ge , Huang Chuan 
Published: February 2024

Abstract
In response to heavy metal stress, the RNA-binding protein (RBP) gawky translocates into the nucleus and acts as a chromatin-interacting factor to activate the transcription of many stress-responsive genes. However, the upstream regulators of gawky-mediated transcription and their mechanistic details remain unknown. Here, we identified a class of metal-responsive element-containing circRNAs (MRE circRNAs) which specifically interact with gawky during copper stress. Using classic stress-responsive genes as a readout (Drosophila MT), we found that overexpression of MRE circRNAs led to a significant repression in stress-induced transcription. Mechanistically, MRE circRNAs promote the dissociation of gawky from chromatin and increase its aberrant cytoplasmic accumulation, which ultimately impedes the loading of RNA polymerase II to the active gene loci. The MRE motif serves as an important RNA regulon for maintaining the circRNA–gawky interaction, loss of which impaired the inhibitory effects of MRE circRNAs on gawky. Through RNA-seq analyses, we then identified over 500 additional stress-responsive genes whose induced transcription was attenuated upon MRE circRNA overexpression. Finally, we uncovered the physiological relevance of MRE circRNA-mediated regulation in cellular defense against copper overloading. Taken together, this study proposes that the circRNA-RBP-chromatin axis may represent a fundamental regulatory network for gene expression in eukaryotic cells.
The Uprisings of Gaza: How Geopolitical Crises Have Reshaped Academic Communities from Tahrir to Kyiv
Authors: Cooley Alexander 
Published: February 2024

Abstract
The Arab uprisings spawned a new body of theoretical, empirical, and methodological advances by political scientists of the Middle East. This essay reflects upon the contributions of the edited volume The Political Science of the Middle East: Theory and Research since the Arab Uprisings to address three occurring central issues at the intersection of regional studies and political science that are affected by geopolitical shocks: how shocks highlight previously neglected topics and actors; how they subsequently discredit and privilege certain disciplines and methods; and how they recast the role of academic research within global communities of knowledge and policy-making. Topics such as the adaptation of authoritarianism, the role of social media, and the onset of multipolar politics, addressed by the volume on the Middle East, are compared with similar processes that have informed the evolution of social science research in the post-Communist states. The final section reflects on how two contemporary conflicts—Russia's invasion of Ukraine and the Hamas-Israel conflict—have affected the American academy, including student protests at American universities, university policies, and academic freedom.
Matrix Regularization for Gauge Theories
Authors: Adachi Hiroyuki , Ishiki Goro , Kanno Satoshi 
Published: February 2024

Abstract
We consider how gauge theories can be described by matrix models. Conventional matrix regularization is defined for scalar functions and is not applicable to gauge fields, which are connections of fiber bundles. We clarify how the degrees of freedom of gauge fields are related to the matrix degrees of freedom, by formulating the Seiberg–Witten map between them.
Clinical characteristics and induced pluripotent stem cells (iPSCs) disease model of Fabry disease caused by a novel GLA mutation
Authors: Gao L , Lu Z , Zhang Y , Liu L , Sun J , Fu H , Mao J , Hu L 
Published: February 2024

Abstract

Background
Fabry disease (FD) is a rare X-linked inherited disease caused by mutations in the galactosidase alpha (GLA) gene. We established a cohort of FD patients and performed whole-exome sequencing to identify some novel mutations.

Aim
The aim of this study is to investigate the etiology of the novel mutation (c.72G &gt; A, p. Trp24*)in the GLA gene in affected patients by using induced pluripotent stem cells (iPSCs) as a valuable tool.

Methods
We explored the clinical implications of this proband and examined the deleteriousness and conservation of the mutation site through bioinformatics analysis. Simultaneously, we collected the peripheral blood mononuclear cells of the affected patient, then reprogrammed them into iPSCs and assessed their enzymatic activity to confirm the function of lysosomal enzyme α-galactosidase A (α-Gal A).

Results
Clinical examination of the patient demonstrated a classical FD, such as neuropathic pain, gastrointestinal disorders, deficiency of α-Gal A activity and accumulation of Lyso-Gb-3. The novel mutation located on the N-terminal region, leading to a truncation of the protein and remaining only 24 amino acids. The α-Gal A activity of the patient-specific iPSC (iPS-FD) was significantly lower (60%) than that of normal iPSCs derived from healthy donors (iPS-B1).

Conclusion
This work not only elucidated the etiology of novel mutations in affected patients but also highlighted the utility of iPSCs as a valuable tool for clarifying the molecular mechanisms and providing new insights into the therapy of FD.
Diagnostic value of a novel salivary gland ultrasound scoring system in IgG4-related sialadenitis
Authors: Zhou Mingzhu , Liu Yanying , Zhang Shanshan , Xie Xiaoyan , Li Wei , Cui Li , Zhao Hanxue , Tang Sumei , Hu Xiangdong , Wu Shanshan , Peng Jiajing , Huang Huilian , Ren Wei , Zhang Ying , Xu Ning , Sun Pengfei , Liu Yiqun , Zhang Zuyan , Yu Guangyan , Su Yin 
Published: February 2024

Abstract

Objectives
To develop a novel ultrasound scoring system for the major salivary glands in patients with immunoglobulin G4-related sialadenitis (IgG4-RS) and assess its diagnostic value in a multicentre cohort of Chinese patients.

Methods
Twenty clinicians (rheumatologists, stomatologists and radiologists) participated. The study was conducted in four steps: (i) defining the ultrasonography (US) elements, (ii) developing a novel ultrasound scoring system for US of the salivary glands, (iii) evaluation of inter- and intra-reader reliabilities using the new ultrasound scoring system, and (iv) assessing the diagnostic value of this novel ultrasound scoring system in IgG4-RS patients in a Chinese multicentre cohort.

Results
A novel ultrasound scoring system for the salivary glands was developed, with total scores ranging from 0 to 34. The inter- and intra-reader reliabilities of the ultrasound scoring system were excellent (0.972 and 0.940, respectively). A total of 470 people were recruited in this study; 187 patients were diagnosed with IgG4-RS, and the remaining 283 people were diagnosed with non-IgG4-RS. Patients with IgG4-RS group had significantly higher US scores than the non-IgG4-RS group (mean US score = 16 vs 4, P &lt; 0.001). The calculated area under the curve for the total US score was 0.852 (95% CI: 0.814, 0.891). The total US scores ≥9 showed a sensitivity of 75.4% and a specificity of 91.9%. Association analysis showed a positive correlation between total US scores and serum IgG4 levels and hypocomplementaemia (r = 0.221 and r = 0.349, respectively; P = 0.002 and P &lt; 0.001, respectively) and a negative correlation between total US scores and serum C3 and C4 levels (r = −0.210 and r = −0.303, respectively; P = 0.005 and P &lt; 0.001, respectively).

Conclusion
A novel semiquantitative ultrasound scoring system for patients with IgG4-RS was developed, with good diagnostic performance. The inter- and intra-reader reliabilities were excellent. US scores were correlated with IgG4, C3 and C4 levels and hypocomplementaemia.
Echoes from the Cretaceous: new fossils shed light on the evolution of host detection and concealed ovipositor apparatus in the parasitoid wasp superfamily Orussoidea (Hymenoptera)
Authors: Vilhelmsen Lars , Boudinot Brendon , Jenkins Shaw Josh , Hammel Jörg U , Perrichot Vincent 
Published: February 2024

Abstract
†Kryptovelona carstengroehni gen. et sp. nov. and †Orussus juttagroehnae sp. nov. are the first female members of the parasitoid wasp family Orussidae recorded from Baltic amber. We describe them, including relevant parts of the internal anatomy examined with synchrotron scanning. The fossils display a number of modifications in the antennae and foreleg correlated with the specialized host-detection mechanism, and in the ovipositor apparatus, as well as in the thorax and abdomen for accommodating the internalized ovipositor. The presence of these and other features places them as crown-group members of the Orussidae, as demonstrated by Bayesian phylogenetic analyses. The recently described stem-group orussoid fossils from Burmese amber, the probable female †Cretorussus vilhelmseni, and probable male †Burmorussus mirabilis (both placed in Burmorussidae), were also included in the dataset. By comparing the new Baltic amber taxa with †Cretorussus, it is possible to trace the progressive refinement of the echolocation mechanism through reductions in the number of antennomeres and foreleg tarsomeres. Unfortunately, †Cretorussus does not have the posterior part of the abdomen with the ovipositor preserved. Nevertheless, it is possible to infer that the putative echolocation mechanism for host detection evolved at least 100 Mya, whereas the concealed ovipositor apparatus has not been documented in fossils older than approx. 35 Mya.
Soil Type and Associated Microbiome Influence Chitin's Growth Promotion Effect in Lettuce
Authors: Kaufmann Moritz , Li Leilei , Van Poucke Christof , Rhyner Nicola , De Tender Caroline , Uyttendaele Mieke , Heyndrickx Marc , Zipfel Cyril , Pothier Joël F. , Cottyn Bart 
Published: February 2024

Chitin amendment of peat substrate has been proven effective in promoting lettuce growth and increasing phenolic compounds in lettuce seedlings. However, the effect of chitin soil amendment on lettuce growth in mineral soil remains unexplored. The effect of chitin amendment of mineral soil on lettuce growth and metabolite changes was investigated for the first time in the present study in comparison with chitin-amended peat substrate. Our findings showed that chitin addition in peat substrate increased lettuce head weight by approximately 50% at harvest, whereas this increase was 30% when chitin was added to mineral soil. Targeted metabolomics analysis indicated that chitin addition affected the phenolic compounds in lettuce seedlings, but this effect varied between soil types. Moreover, untargeted metabolomics analysis suggested that using peat substrate or mineral soil had a greater influence on produced lettuce metabolites than chitin addition. Rhizobiome analysis showed that specifically Mortierellaceae family members, known for chitin degradation and plant growth promotion, significantly increased in peat substrate upon chitin treatment. In mineral soil, three bacterial genera and five fungi, including known plant-growth-promoting genera, were significantly more abundant upon chitin treatment but Mortierellaceae family members were not. We assume that the observed effects primarily stem from soil characteristics and from chitin-induced alterations in rhizobiome composition, particularly the presence of Mortierellaceae members, leading to promoted lettuce growth. Despite the variability, chitin remains an environmentally friendly alternative to synthetic fertilizers in lettuce production, but its beneficial effects are dependent on rhizobiome composition, which should be considered before chitin application. [Formula: see text] Copyright © 2024 The Author(s). This is an open access article distributed under the CC BY-NC-ND 4.0 International license .