bluuebunny/crossref_metadata_2025_split huggingface dataset:
Histologic and Duplex Comparison of the Perclose and Angio-Seal Percutaneous Closure Devices
Authors: Gargiulo Nicholas J. , Veith Frank J. , Ohki Takao , Scher Lawrence A. , Berdejo George L. , Lipsitz Evan C. , Menegus Mark , Greenberg Mark 
Published: May 2007

The intravascular and extravascular effects of percutaneous closure devices have not been well studied. We assessed the performance and healing characteristics in dogs of two devices approved by the US Food and Drug Administration. Nine adult male dogs were anesthesized prior to percutaneous access of both femoral arteries with a 6F sheath. All dogs were systemically heparinized to an activated clotting time (ACT) > 250 seconds. Duplex sonography was performed preoperatively to measure vessel diameter and flow velocity. In each dog, one of two devices (Perclose, Abbot Laboratories, Abbott Park, IL or Angio-Seal, St. Jude Medical, St. Paul, MN) was randomly deployed into one of the two femoral arteries. The other device was deployed on the opposite side. Duplex sonography was repeated immediately after deployment and 28 days later to measure changes in vessel diameter and flow velocity. At 28 days, angiography was performed on both femoral arteries before they were removed for histologic evaluation. The time required to excise each vessel reflected the degree of scarring. Hemostasis time for the Angio-Seal device far surpassed the Perclose device (39 ± 7 vs 0 minutes; p < .05). Vessel narrowing was observed only at 28 days after deployment of the Angio-Seal device ( p < .05). Extensive extravascular scarring was observed with the Angio-Seal device, which resulted in a longer femoral artery dissection time and greater periadventitial scar thickness compared with the Perclose device ( p < .05). When compared with the Perclose suture closure device, the Angio-Seal collagen plug closure device prolonged hemostasis time and produced greater vessel narrowing and periadventitial inflammation (extravascular scarring) in a canine model at 4 weeks.
Inadvertent Arterial Injury Secondary to Treatment of Venous Insufficiency
Authors: Nitecki Samy S. , Bass Arie 
Published: May 2007

Arterial injury during treatment of varicose veins is a rare but devastating complication that can lead to leg amputation. Approximately 6,000 patients were treated by either surgery (4,800 patients treated by ligation, stripping, and stub avulsion) or ultrasound-guided foam sclerotherapy (USGS) (1,200 patients) in the last 7 years for venous insufficiency at three medical centers. Six patients (0.1%) sustained inadvertent arterial injury. The incidence of arterial injury during surgery was 0.06% (3 of 4,800) and was of a mechanical nature amenable to repair. None of these patients had tissue loss. The injury during USGS (0.25%, 3 of 1,200) was of a chemical and irreversible nature. All three patients suffered tissue loss. In our experience, the incidence of arterial injuries during USGS is four times higher than during traditional surgery and carries a much higher risk of tissue loss. Although experience, technical skill, and awareness of this complication help reduce the incidence of arterial injury during surgery, they seem to offer no protection during USGS. Careful mapping of the arterial venous communications and avoidance of high-risk zones will help prevent this complication.
Huge Popliteal Arterial Aneurysms in Behçet's Syndrome: Is Ligation an Alternative Treatment?
Authors: Goz Mustafa , Cakir Omer , Eren M.Nesimi 
Published: May 2007

Behçet's syndrome is a multisystemic disease characterized by relapsing uveitis, oral and genital ulcerations, and vascular system involvement. The vascular involvement is seen as venous occlusion, arterial occlusion, and aneurysm formation in this disease, and the surgical treatment of a Behçet's aneurysm has technical difficulties. In this report, we suggest that the huge popliteal artery aneurysm in Behçet's syndrome can be treated by ligation of the popliteal artery. A 58-year-old male patient was admitted to our clinic because of an infrapopliteal great mass at the left leg. Color Doppler ultrasonography and arteriography revealed a 71 × 54 mm aneurysmal dilatation at the distal popliteal artery. Surgery did not reveal any suitable arterial formation for bypass to the distal area of the popliteal artery and tibial arteries. For this reason, we applied ligation of aneurysmal dilatation at the distal popliteal artery. The patient tolerated the operation well and had no signs of ischemia during the postoperative period. In conclusion, especially in aneurysm of arteries such as the popliteal artery, which has critical importance for maintaining distal perfusion, ligation may be a treatment method if there are no other alternatives.
A non‐ancestral RPGR missense mutation in families with either recessive or semi‐dominant X‐linked retinitis pigmentosa
Authors: Banin Eyal , Mizrahi‐Meissonnier Liliana , Neis Ruhama , Silverstein Shira , Magyar István , Abeliovich Dvorah , Roepman Ronald , Berger Wolfgang , Rosenberg Thomas , Sharon Dror 
Published: May 2007

AbstractMost X‐linked diseases show a recessive pattern of inheritance in which female carriers are unaffected. In X‐linked retinitis pigmentosa (XLRP), however, both recessive and semi‐dominant inheritance patterns have been reported. We identified an Israeli family with semi‐dominant XLRP due to a missense mutation (p.G275S) in the RPGR gene. The mutation was previously reported in two Danish families with recessive XLRP. Obligate carriers from the two Danish families had no visual complaints and normal to slightly reduced retinal function, while those from the Israeli family suffered from high myopia, low visual acuity, constricted visual fields, and severely reduced electroretinogram (ERG) amplitudes. The disease‐related RPGR haplotype of the Israeli family was found to be different from the one found in the two Danish families, indicating that the mutation arose twice independently on different X‐chromosome backgrounds. A series of genetic analyses excluded skewed X‐inactivation pattern, chromosomal abnormalities, distorted RPGR expression level, and mutations in candidate genes as the cause for the differences in disease severity of female carriers. To the best of our knowledge, this is the first detailed analysis of an identical mutation causing either a recessive or a semi‐dominant X‐linked pattern of disease in different families. Our results indicate that an additional gene (or genes), linked to RPGR, modulate disease expression in severely affected carriers. These may be related to the high myopia concomitantly found in affected carriers from the Israeli family. © 2007 Wiley‐Liss, Inc.
Successful neurological outcome of a child with classical phenylketonuria and acute lymphoblastic leukemia: A 7‐year follow‐up
Authors: Wang Cheng , Camfield Carol S. , Fernandez Conrad V. , Hurley Terry , Campbell Karen 
Published: May 2007

AbstractWe report on the medical management and outcome of a child with classical phenylketonuria (PKU) who developed acute lymphoblastic leukemia (ALL). Chemotherapy began at 24 months of age. Initial problems associated with treatment lead to remarkable releases of phenylalanine, a neurotoxin. Causes included increased catabolism secondary to tumor lysis and chemotherapy, as well as infection, intermittent fasting and anorexia. Medical management involved daily monitoring of Phe levels and major changes in the amount of medical formula and the intake of protein containing foods in the diet. The child is currently in remission from ALL and has a normal neurodevelopmental outcome 7 years after the ALL diagnosis. © 2007 Wiley‐Liss, Inc.
Synthesis, characterization and in vitro cytotoxicity of homobimetallic complexes of palladium(II) with 2‐thiouracil ligands. Crystal structure of [Pd2(TU)(PPh3)3Cl2]
Authors: Shaheen Farkhanda , Badashah Amin , Gielen Marcel , Marchio L. , de Vos Dick , Kaleem Khosa M. 
Published: May 2007

AbstractSquare planar metallic and homonuclear bimetallic complexes of Pd(II) with 2‐thiouracil (HTU) and organophosphines have been synthesized and characterized by FT‐IR and multinuclear 1H, 13C, 31P NMR spectroscopy. The thiouracil ligand TU acts as bidentate, is bound through the thioxo moiety and the endo amino group and forms a bridge between a PdCl(R3P) and a PdCl(R3P)2 moiety [R3P = Ph3P (o‐tolyl)3P, ClPh2P] in the homonuclear bimetallic complexes. The square planar geometry around Pd(II) has been confirmed for these complexes by a single‐crystal X‐ray diffraction study of compound 1, [Pd2(TU)(PPh3)3Cl2]. These compounds were also screened against human tumor cell lines and showed promising in vitro cytotoxicity. Copyright © 2007 John Wiley & Sons, Ltd.
Synthesis of polyacrylamide‐wrapped carbon nanotubes and their lubrication properties as water‐based fluids
Authors: Liu Yifeng , Guan Wenchao , Li Xuefeng , Huang Mingxing 
Published: May 2007

AbstractCarbon nanotubes (CNTs) wrapped by polyacrylamide (PAM) were synthesized through the insitu free‐radical polymerization of acrylamide in the presence of the CNTs. Transmission electron microscopy was used to characterize the synthetic CNTs/PAM. This product dissolved easily in water. The effects of the synthetic product as an additive on the load‐carrying capacity and antiwear behavior of a water‐based fluid were investigated with a four‐ball tribotester. The worn surface images of the steel balls were observed by scanning electron microscopy. The results showed that CNTs/PAM at a certain concentration in the base stock effectively raised the load‐carrying capacity and antiwear ability. © 2007 Wiley Periodicals, Inc. J Appl Polym Sci, 2007
Comparative analysis of the structural parameters and strength properties of polyacrylonitrile fibers containing ceramic nanoadditives
Authors: Mikołajczyk Teresa , Boguń Maciej , Rabiej Stanisław 
Published: May 2007

AbstractThe structural parameters and strength properties of three types of new‐generation precursor polyacrylonitrile fibers are comparatively analyzed. These fibers, after the carbonization process, can be used as implants supporting the process of bone reconstruction. They are characterized by a high tenacity ranging from 21 to 41 cN/tex. Tests and measurements have shown that the presence of nanoadditives causes a clear increase in the degree of fiber crystallinity. Moreover, the tenacity of the fibers can be considerably increased by the grinding of nanoadditive agglomerates with ultrasound. © 2007 Wiley Periodicals, Inc. J Appl Polym Sci, 2007
Inherent biases in decision support systems: the influence of optimistic and pessimistic DSS on choice, affect, and attitudes
Authors: Korhonen Pekka , Mano Haim , Stenfors Sari , Wallenius Jyrki 
Published: May 2007

AbstractThis study investigates the influence of a decision aid on decision makers' model‐based choices, emotions during the use of the model, and attitudes towards the model. A time allocation decision model was biased to purposefully provide optimistic or pessimistic criterion levels, on which subjects based their allocations. The results of our experiment indicate that the degree of “optimism” and “pessimism” inherent in the decision model had a significant impact on the decision maker's choices of criterion values, with optimism leading to higher criterion level choices and pessimism to lower levels. Furthermore, compared to pessimistic models, optimistic models significantly improved the decision makers' emotional states and, to some degree, their attitudes towards the decision aid. The implications of these conscious and sub‐conscious influences on decision makers' choices, emotions, and attitudes are discussed and the need for model‐builders and users to be aware of them is highlighted. Copyright © 2007 John Wiley & Sons, Ltd.
An Algorithm for Calculation of n‐Dimensional Nonlinear Dependencies – Behaviour Tests on Rats
Authors: Kniepert E. , Kniepert A. 
Published: May 2007

AbstractThe evaluation of the data obtained during the behaviour tests always leads to the problem of multiple correlation, very often with non‐linear dependencies on the target. All mathematical and statistical procedures that have been used so far are based on the assumption of an equation for the desired correlation for which parameters and related statistical equivalents are determined eventually. The MODAK system applied here (MODAK = algorithms of modelling for the calculation of multi‐dimensional non‐linear mathematical models) breaks down a complex correlation into individual dependencies in a mathematical and statistical way and selects suitable equations for each of them independently and determines the corresponding parameters. The numerical example evaluates data of behaviour tests on rats.First results obtained on the correlations of various behaviour tests indicate both the possibility of selecting suitable tests independent of each other and a better interpretation of the observed patterns of behaviour taking into account the interrelations between the tests.In addition, MODAK is a method which can be applied as a matter of course in a general way to all cases which call for the reduction and analysis of data occurring in process and system analysis and in the evaluation of test results requiring statistical modelling. So far, MODAK applications range from engineering sciences to medicine.
A Method for Analyzing Nonlinear Models When the Data are from a Split‐plot or Repeated Measures Design
Authors: Schaff D. A. , Milliken G. A. , Clayberg C. D. 
Published: May 2007

AbstractStatistical methods are described which can be used to compare treatments where the response model is nonlinear and the experimental design includes split‐plots or repeated measures. The nonlinear analysis of covariance is described for a two‐way treatment structure in a split‐plot design structure, the usual split‐plot experimental design. Evaluating heat tolerance in common beans as a function of temperature is used as an example to demonstrate the methodology.
Quasi‐fixed Points w.r.t. the Height Growth Curve
Authors: Masuyama M. 
Published: May 2007

AbstractWhen height growth curves are linearized, these lines are nearly concurrent after the growth spurt (Masuyama, 1979, 1982b, 1983), i.e. there exists a nearly fixed point, which seems to correspond to the upper limit of the growth of the mean person. On other hand, before the spurt, there seems to exist a nearly fixed point on the mean distance‐velocity curve between 4 and 6 years of age. To grasp easily the existence of nearly fixed point, instead of many straight lines surrounding this point, we represent them dually by many points surrounding a straight line.
Sample Size Requirements in Studies of the Etiologic Fraction
Authors: Smith Judith A. , McHugh R. B. 
Published: May 2007

AbstractThis paper outlines methods of determining sample size for epidemiologic research in studies of the etiologic fraction. The basic model with a dichotomous disease and a single dichotomous exposure factor is considered. To determine sample size, the researcher must specify: the magnitude of the etiologic fraction ε to be detected as statistically significant, the level of significance α, the power 1 ‐ β of the test, p the proportion of the population exposed to the risk factor and R the proportion of the population with the disease. Sample size formulas and tables are presented for the case‐control, cohort and cross‐sectional designs. Optimal allocation considerations are examined to minimize cost for a specified power. Extensive use is made of Walter's results concerning the asymptotic variance of the maximum likelihood estimator of the etiologic fraction for the three epidemiologic study designs.
Profile Analysis of Variance as a Tool for Analyzing Correlated Responses in Experimental Ecology
Authors: Simms E. L. , Burdick D. S. 
Published: May 2007

AbstractIn ecological studies experiments are often designed in which the variables to be compared are not statistically independent. Examples include repeated measures of the same response by the same individual at different times, measurement of several traits on the same individual, and measurements taken from two or more types of organisms present together in the same experimental unit (e.g.) plot, cage, pond, etc.). This type of design violates several assumptions of the standard analysis of variance. These assumptions are examined and profile analysis, a modification of the standard analysis of variance which does not depend upon these assumptions, is presented. Simple instructions for performing profile analysis of variance using two common statistical packages for mainframe computers are provided in an appendix.
Generalized Walker‐Duncan Procedure for Obtaining Maximum Likelihood Estimates of Parameters of Logistic Discriminant Function
Authors: Keusińska Ewa 
Published: May 2007

AbstractA recursive method of obtaining the maximum likelihood estimates of the parameters of the quadratic logistic discriminant function is presented. This method is an extension of the Walker and Duncan procedure (1967) proposed for the linear logistic discriminant function in a dichotomous case. A generalization of the method to the problem of discrimination between several populations is also given in the paper. It works for both linear and quadratic logistic discriminant function. After an estimation of the parameters of the logistic function a classification can be performed. An example of application of the method to automatic diagnosis of some respiratory diseases is presented. Comparison with the standard procedures used for the estimation is done by a short simulation study.
A Robust Test for Multi‐Sample Location Problems with Unequal Group Variances and Nonnormality
Authors: Tabatabai M. A. , Tan W. Y. 
Published: May 2007

AbstractA robust test (to be referred to as M* test) is proposed for testing equality of several group means without assuming normality and equality of variances. This test statistic is obtained by combining Tiku's MML robust procedure with the James statistic. Monte Carlo simulation studies indicate that the M* test is more powerful than the Welch test, the James test, and the tests based on Huber's M‐estimators over a wide range of nonnormal universes. It is also more powerful than the Brown and Forsythe test under most of nonnormal distributions and has substantially the same power as the Brown and Forsythe test under normal distribution. Comparing with Tan‐Tabatabai test, M* is almost as powerful as Tan‐Tabatabai test.
Use of Ranks in Comparisons of Variability in the Non‐Normal Populations
Authors: Rai S. C. , Sarup Shanti 
Published: May 2007

AbstractA method of analysis for comparing the variability of two samples drawn from two populations has been developed. The method is also suitable for the nonnumeric form of data. A test based on ordered observations for testing the null hypothesis of equality of two variances has been given. The test statistic is a function of the sum of ranks assigned to smaller size sample. Ranking procedure has been modified to depict the variability in the data by the sum of ranks. The null distribution of the test‐statistic has been worked out for small samples and it turns out to be chi‐square distribution for large samples. The analytical procedure has been explained by a numerical example on the productivity and production of rice and wheat in India from 1950–51 to 1983–84.
Bayes's Theorem and the Analysis of Binomial Random Variables
Authors: Walters D. E. 
Published: May 2007

AbstractA very practical application of Bayes's theorem, for the analysis of binomial random variables, is presented. Previous papers (Walters, 1985; Walters, 1986a) have already demonstrated the reliability of the technique for one, or two random variables, and the extension of the approach to several random variables is described. Two biometrical examples are used to illustrate the method.
On the Statistical Inference from Survival Experiments with Two Types of Failure
Authors: Rachev S. T. , Yakovlev A. Yu. , Kadyrova N. O. , Myasnikova E. M. 
Published: May 2007

AbstractFormulated in terms of latent failure times a survival model with two dependent competing risks is considered. Using this model, it is possible to introduce the probabilistic characteristics of each type of failure contribution to the joint effect of two damaging agents. Confidence bounds for such characteristics are given.
On Generalized Log‐Logistic Model for Censored Survival Data
Authors: Singh Karan P. , Lee Carl M.‐S. , George E. Olusegun 
Published: May 2007

AbstractIn the analysis of survival data with parametric models, it is well known that the Weibull model is not suitable for modeling cases where the hazard rate is non‐monotonic. For such cases, log‐logistic model is frequently used. However, due to the symmetric property of the log‐logistic model, it may be poor for the cases where the hazard rate is skewed or heavily tailed. In this paper, we suggest a generalization of the log‐logistic model by introducing a shape parameter. This generalized model is then applied to fit the lung cancer data of Prentice (1973). The results seem to improve over those obtained by using the log‐logistic model.
Modelling Survival Data to Examine Length of Treatment Effectiveness in a Clinical Trial
Authors: Slymen Donald J. 
Published: May 2007

AbstractIn some clinical trials where the experimental treatment is found to be effective in increasing survival, an important question is how long should the patient remain under treatment. Although the trial may not be designed to specifically answer this question, comparisons of the hazard curves among the treatment groups can yield some useful information. The survival data may be modelled using a flexible set of hazard functions and specific models are then chosen for further examination. This paper illustrates the approach using data from the Beta‐Blocker Heart Attack Trial. Parametric and semi‐parametric models are fitted and likelihood methods are used to assess length of treatment effectiveness.
An Application of the Orthogonal Series Estimators in the Classification Of Mixed Variables
Authors: Wojciechowski T. 
Published: May 2007

AbstractSuppose we have two general populations π1, π2. Each object belonging to the population πi, i = 1, 2 is characterized by a random vector X′ = (Z′, Y′), where Z is discrete and Y is continuous. On a certain element which is a member of a one of the two populations a realization π′0=(z′0, y′0) of the random vector X has been observed and we want to classify that element. One of the possible methods of doing it is to estimate the density functions of X in π1 and π2 and construct an estimated classification rule. In this paper the density estimates based on the orthogonal series (Hall, 1983) will be employed and the classification rule will be examined on a practical example.
The Statistical Analysis of Clustering of Events
Authors: Nagelkerke N. J. D. , Oskam S. , Fidler V. , Yzermans C. J. 
Published: May 2007

AbstractThe concept of clustering of events within elements of a population is explored. Test statistics for testing the null hypothesis of a Poisson process versus the alternative of clustering are developed and their conditional null expectation and variance are derived. An application to an EEG registration of an epilepsy patient is presented.