bluuebunny/crossref_metadata_2025_split huggingface dataset:
Impaired specific cellular immunity to the varicella-zoster virus in patients with herpes zoster oticus
Authors: Ikeda Minoru , Hiroshige Kouichi , Abiko Yuzuru , Onoda Keiko 
Published: November 2007

AbstractThe possible involvement of depression on cellular immunity in reactivation of varicella-zoster virus (VZV) in herpes zoster oticus was investigated. The subjects comprised 59 cases of herpes zoster oticus, 33 cases of herpes zoster sine herpete (ZSH) with facial paralysis, and 205 cases of Bell's palsy. The transformation rate of lymphocytes to phytohaemagglutinin in herpes zoster oticus tended to be lower than that in Bell's palsy. In skin tests with purified protein derivatives of tuberculin, the positivity rate in herpes zoster oticus was significantly lower than that in Bell's palsy (p<0.015). In skin tests using VZV antigen, the positivity rate in herpes zoster oticus and ZSH were significantly lower than that of Bell's palsy (p<0.001 andp<0.015, respectively). Thus, it was noted that cellular immunity, especially specific cellular immunity against VZV, was significantly depressed in herpes zoster oticus and ZSH. We consider that depression of specific cellular immunity plays an important role in triggering reactivation of VZV and onset of these diseases.
Laryngeal carcinoma in younger patients
Authors: Petrović Z. , Stojčić G. , Ješić S. 
Published: November 2007

AbstractDuring the period 1976–1988, 988 patients were treated surgically for laryngeal cancer of whom 61 were below the age of 40 years.In 29 patients the tumour was localized in the supraglottis, and in 32 in the glottis. T1tumour was present in 32 (52.46 per cent), and T2tumour in six (9.84 percent) patients. Advanced T3and T4tumours were present in 13 (21.31 per cent), and (16.39 per cent) patients respectively. The majority had clinically negative findings in the neck (N0). Conservative or reconstructive surgery was applied in 39 (63.93 per cent), and radical in 22 (36.07 per cent) patients. Planned post-operative radiotherapy was carried out in 28 (45. 90 per cent) patients.The five-year survival rate of the studied patients was 83.61 per cent (51/61). The five-year survival rate of the patients with laryngeal carcinomas within the same period was 68.32 per cent (675/988). There was no significant difference in survival rate: X2= 0.018, DF = 1,p>0.05.
Pulsed dye laser lithotripsy of submandibular gland salivary calculus
Authors: Ito Hirotaka , Baba Shunkichi 
Published: November 2007

AbstractAn in vivo study was performed to evaluate the use of pulsed-dye laser beam for the fragmentation of salivary calculus. In accordance with the absorption and reflection spectra of sections of salivary stones, optimal fragmentation was achieved with a pulsed-dye laser with a pulse width of 1.4 μm and tuned to a wavelength of 504 nm. Further studies on particle size were conducted, and a new “sialoendoscope” technique was developed. Fifteen patients with sialolithiasis of the submandibular gland were treated. Under continuous endoscopic monitoring laser-induced shock wave lithotripsy was performed. In six patients complete fragmentation and removal of the salivary stones was achieved and in another patient 50 per cent fragmentation was sufficient to restore salivary flow. Laser lithotripsy of salivary stones with endoscopic monitoring permits treatment on an outpatient basis with little inconvenience to the patient, and this is a breakthrough in otolaryngology.
Transnasal endoscopic surgery in juvenile nasopharyngeal angiofibroma
Authors: Kamel Reda H. 
Published: November 2007

AbstractA case of angiofibroma limited to the right posterior nasal cavity, nasopharynx, and pterygopalatine fossa was operated upon transnasally under endoscopic control. The tumour was completely excised without complications. Endoscopic follow-up for the next two years and contrast computed tomography (CT) excluded any residual tumour or recurrence. The advantages, limitations and possible complications of this approach are discussed. It seems that in limited lesions of angiofibroma, the option of a transnasal endoscopic approach could be cautiously considered by experienced surgeons.
Unusual anterior course of the sigmoid sinus: report of a case and review of the literature
Authors: Gangopadhyay K. , McArthur P. D. , Larsson S. G. 
Published: November 2007

AbstractThe position and dimensions of the jugular bulb and the venous dural sinuses vary considerably. While the anatomical variations of the jugular bulb have been extensively reported in the literature, that of the sigmoid sinus have been reported only rarely. We report a case of unusual anterior course of the vertical segment of the sigmoid sinus which was encountered during an attempted myringoplasty. Anomalies of the jugular bulb in general are also described.
Audio-vestibular manifestations of Chiari malformation and outcome of surgical decompression: A case report
Authors: Ahmmed A. U. , Mackenzie I. , Das V. K. , Chatterjee S. , Lye R. H. 
Published: November 2007

AbstractSensorineural hearing loss, tinnitus, dizziness and ataxia are recognised symptoms associated with Chiari malformations but they are rarely the presenting complaints. Patients with such symptoms are frequently referred to otolaryngologists and audiological physicians. We report a case of a 13-year-old girl who presented complaining of tinnitus and impaired hearing, and was subsequently diagnosed as having a type I Chiari malformation. Pure tone audiogram showed a mild hearing impairment on the left side and the speech audiogram was normal. Auditory brain stem responses and the electronystagmography were abnormal. The patient underwent posterior fossa decompression following which her tinnitus disappeared, the hearing problem recovered and some of the abnormal electrophysiological parameters were corrected.
Fractured tracheostomy tube: an overlooked foreign body
Authors: Gupta S. C. , Ahluwalia Hemant 
Published: November 2007

AbstractA rare case of an overlooked fractured metallic Fuller's tracheostomy tube in the posterior basal segment of the left lung is reported along with a review of the literature. Incidence, aetiology, delay in diagnosis, complications and management of overlooked foreign bodies are discussed. Various factors contributing to the fracture of tracheostomy tubes are reviewed.
A cost effective screening protocol for vestibular schwannoma in the late 90s
Authors: Ravi K. V. , Wells S. C. 
Published: November 2007

AbstractMagnetic resonance imaging (MRI) is the imaging modality of choice in diagnosing vestibular schwannoma (VS). Perceived high costs have prevented clinicians from using it as a screening investigation, although MR scanners are now widely available in the United Kingdon. In a retrospective study, the clinical records of all the patients who presented to the ENT department of Taunton and Someerset NHS Trust with suspected symptoms of VS during the year 1994 were analysed. The cost of confirming or refuting the diagnosis of VS in each patient ranged from £220.72 to £580.31 depending on the number of hospital visits and investigations performed. This study shows that the routine use of MR scanning for detection of VS is cost effective and more effective than the use of conventional tests.
Nonspecific vertigo with normal otoneurological examination. The role of vestibular laboratory tests
Authors: Gordon Carlos R. , Shupak Avi , Spitzer Orna , Doweck Ilana , Melamed Yehuda 
Published: November 2007

AbstractVestibular larobatory tests are not general necessary in the diagnosis of patients with a clear description of vertigo accompanied by positive otoneurological examination findings. The purpose of the study was to inverstigate the role of conventional vestibular laboratory tests in the diagnosis of patients compaining of hnonspecific vertigo, despite their having a documented normal otoneurological examination. The results patients referred for ambulatory vestibular laroratory testes due to a nonspecific illusion of movement, but with nornal otoneurological examination, were reviewed. Abnormalities were found in the vestibular tests of 35 patients (67 per cent), 22 of whom (63 per cent) were finally diagnosed as having a unilateral perpheral vestibular lesion, and 13(37 per cent) benign positional vertigo. These results suggests that a high percentage of patients with nonspecific vertigo and a normal otoneurologica examination probably suffer from peripheral vestibular dusfunction, which can be objectively documented by the ENG and SHA tests.
Thyroid carcinoma causing fatal laryngeal occlusion
Authors: Carter N. , Milroy C. M. 
Published: November 2007

AbstractPure squamous carcinoma of the thyroid gland is an uncommon tumour and is thought to arise in glands containing metaplastic squamous epithelium. Extrinsic compression or tumour invasion of the larynx causing fatal respiratory obstruction are recognized complications. We report a case of primary squamous carcinoma of the thyroid gland where obstruction of laryngeal mucous gland outflow resulted in fatal laryngeal compression. This appears to be the first description of such a sequence of events.
The bone anchored hearing aid (BAHA) in chronic suppurative otitis media (CSOM)
Authors: Macnamara Marcelle , Phillips David , Proops David W. 
Published: November 2007

AbstractBone anchored hearing aids are gaining wide acceptability in the treatment of patients with congenital ear problems, chronic suppurative otitis media (CSOM) and in some cases otosclerosis. To date little information on the effect of the bone anchored hearing aid on the symptoms of chronic suppurative otitis is available. This retrospective study based on notes review and telephone interviews was to assess the outcome of bone anchored hearing aid surgery in patients with CSOM in terms of: ear discharge; surgical techniques and complications; the number of hours the aid is worn compared with the previous aid.One hundred and forty-two patients were fitted with bone anchored hearing aids without additional prostheses in Birmingham between 1989 and 1995. Sixty-nine (48.5 per cent) of these were for chronic suppurative otitis media, 45 of these were female and 24 were male with a mean age of 58 years. Most (85 per cent) had undergone previous ear surgery with 65 per cent having mastoid surgery. Ninety-eight per cent of this patient group had undergone single stage surgery and 65 per cent under local anaesthetic as a day case. A variety of techniques for soft tissue reduction were employed.The mean follow-up time for these patients was 24 months (range one month to seven years). No patients experienced worse discharge following their BAHA and 84 per cent had significantly reduced discharge, 16 per cent had no change. Complications included skin reactions, 15; failure to integrate, one; late loss of fixture, three. Seventy-three per cent wore their bone anchored hearing aid more than eight hours per day and 58 per cent were more satisfied with their bone anchored hearing aid than their previous aid.
Self-inflicted traumatic macroglossia
Authors: Alvi Aijaz , Theodoropoulos Philip A. 
Published: November 2007

AbstractMacroglossia is a potentially life-threatening problem. The multiple aetiologies responsible for this condition include cysts, tumours, amyloidosis, angioedema, and infections. Although injuries to the oral cavity are common, self-inflicted traumatic macroglossia is not common. We report a case of a comatose patient with limb contractures and severe trismus who developed entrapment of the tongue with progressive macroglossia and near auto-amputation of the tongue. The importance of early recognition and treatment of tongue entrapment in comatose patients is emphasised since this is a potentially reversible condition.
Atypical carcinoid of larynx: presentation with scalp metastases
Authors: Ereño Cosme , Lopez Jose I. , Sanchez Jose M. 
Published: November 2007

AbstractA case of atypical carcinoid tumour of the larynx in a 72-year-old woman is presented. The neoplasm was located in the supraglottic region and was first manifest by metastases to the scalp. The presence of amyloid-like material and calcitonin-positive cells were features that resembled medullary carcinoma of the thyroid. Clinically, it pursued an aggressive course that led to death 58 months after diagnosis. The literature is reviewed, particularly that regarding the differential diagnosis.
Cochlear implantation in the presence of chronic suppurative otitis media
Authors: Axon P. R. , Mawman D. J. , Upile T. , Ramsden R. T. 
Published: November 2007

AbstractNine patients are presented who underwent cochlear implantation in the presence of chronic suppurative otitis media. Four had a simple tympanic membrane perforation, four had a pre-existing mastoid cavity and one had cholesteatoma in the ear chosen for implantation. Patients with a simple perforation had a staged procedure with myringoplasty followed by cochlear implantation after an interval of three months. Patients with cholesteatoma or with an unstable mastoid cavity were also staged. A mastoidectomy or revision mastoidectomy was performed with obliteration of the middle ear and mastoid using a superiorly pedicled temporalis muscle flap and blind sac closure of the external meatal skin. After a further six months a second stage procedure was performed to confirm that the middle-ear cleft was healthyand to insert the implant. Patients presenting with a stable mastoid cavity underwent obliteration of the cavity and implantation of the electrode as a one-staged procedure. To date there have been no serious problems such as graft breakdown, recurrence of disease or implant extrusion, and all patients are performing well.
CT assessment of jugular foramen dominance and its association with hand preference
Authors: Adams W. M. , Jones R. L. , Chavda S. V. , Pahor A. L. 
Published: November 2007

AbstractThree hundred and seven normal CT scans of the head were prospectively analysed to assess jugular foramen dominance. After assessment, hand preference was elicited. Of these, 276 were right-handed and 31 were left-handed. Of the right-handed patients: 180 had a larger jugular foramen on the right; 63 had a larger jugular foramen on the left; and in 33 no difference could be discerned. Of the left-handed patients: 11 had a larger jugular foramen on the right; 16 hada larger jugular foramen on the left; and in four no difference couldbe discerned. The results suggested a significant association betweenjugular foramen dominance and hand preference.
Anatomical considerations of high jugular bulb in lateral skull base surgery
Authors: Aslan Asim , Falcioni Maurizio , Russo Alessandra , Donato Giuseppe De , Balyan Fatih Ridvan , Taibah Abdelkader , Sanna Mario 
Published: November 2007

AbstractIn order to study high jugular bulb management in lateral skull base surgery, an anatomical study was conducted on 30 temporal bones by examining the relationship between the internal auditory canal (IAC) and the jugular bulb. The following parameters were measured: 1) Height of the jugular bulb (H) … distance between the level of the jugular bulb dome and the line passing through the confluence of the sigmoid sinus with the jugular bulb (SS-JB), 2) Mastoid length (ML) … distance between the mastoid process and middle cranial fossa dura, 3) Distance between the most inferior part of the porus acousticus and jugular bulb dome (A), 4) Distance between the porus acousticus and SS-JB (B). The jugular bulb was defined as high when it occupied more than two thirds of (B). The incidence of a high jugular bulb was 23 per cent in this study. When the jugular bulb was high, the mean (H) and (A) were 9.4 ± 1.9 mm and 2.7 ± 0.5 mm, respectively. (H) was higher on the right side than on the left side. No statistically significant difference was found between small and large mastoids (t-test: p>0.05). It was concluded that when a high jugular bulb was encountered during lateral skull base surgery, the jugular bulb position allows a very small working area inferior to the IAC. In these cases, a 3 or 4 mm depression of the jugular bulb is necessary in order to expose the lower cranial nerves. This can be accomplished by lowering the jugular bulb with the technique already described.
Mast cell ultrastructure in the inferior turbinate and stroma of nasal polyps
Authors: Drake-Lee Adrian , Price Jacqueline 
Published: November 2007

AbstractFourteen unselected adult patients with nasal polyps had ultrastructural examination of mast cells from matching biopsies of the polyp and inferior turbinate. Between three and 10 blocks were examined for each patient in both tissues and every mast cell that had a nucleus was photographed for study. Fifty-three mast cells were found within the stroma of nasal polyps and 54 in the submucosa of the inferior turbinate biopsies. The number of granules ranged between 13 and 167 (mean 60) for polyps and 18 and 148 (mean 61) in the inferior turbinate. The mast cells appeared essentially normal in the inferior turbinate of four patients. The degree of degranulation of the mast cells was calculated as in previous studies and then averaged for both the polyp and the inferior turbinate of each patient. There was greater degranulation in the nasal polyp compared to inferior turbinate (p= 0.03). These results were compared with mast cell degranulation found in the normal nose and in the inferior turbinate of patients with perennial allergic rhinitis which we previously published. The inferior turbinates in these patients were more degranulated than the normal nose (p= 0.0001) but were similar to that found in patients with perennial allergic rhinitis. This suggested that some degree of degranulation may occur throughout the nose in two thirds of the patients with nasal polyps which supports the theory that mast cell reactions are not limited to the polyps in a proportion of patients.
Snoring and oral submucous fibrosis
Authors: Soni N. K. 
Published: November 2007

AbstractForty patients above the age of 40 years with oral submucous fibrosis were studied to determine the frequency and severity of snoring. The results were compared with a controlled group of similar sex and age for presence of snoring. The present study indicates that patients with oral submucous fibrosis having a short and fixed uvula and scarred soft palate are less likely to develop snoring. Thus it is suggested that in laser surgery or in classical uvulopalatopharyngeal surgery, the uvula and soft palate should be reduced in size and volume to the extent of that found in oral submucous fibrosis.
Treatment of recurrent respiratory papillomatosis with argon plasma coagulation
Authors: Bergler W. , Hönig M. , Götte K. , Petroianu G. , Hörmann K. 
Published: November 2007

AbstractExtension of recurrent respiratory papillomatosis (RRP) to the lower airway in children is life-threatening and an extremely difficult condition to treat. We present the case of a seven-year-old girl with progressive RRP since the age of two. Repeated CO2 laser treatment and interferon-alpha treatment could not prevent tracheotomy and spread to the trachea. We used argon plasma coagulation (APC) with flexible endoscopy for the first time for the treatment of RRP. APC gives a controlled limited penetration into the tissue and good control of bleeding. There is no carbonization or vaporization which makes it a suitable method for the treatment of lower airway RRP. After a few treatments with APC, we gained very good control of the disease with no side-effects or complications. The described application of APC seems to be a promising way to treat lower airway RRP.
Tracheoesophageal puncture using a flexible gastroscope and a percutaneous endoscopic gastrostomy set
Authors: Singh V. , Brockbank M. J. , Flower N. , Frost R. A. 
Published: November 2007

AbstractTracheoesophageal puncture is an established procedure for voice restoration following laryngectomy. A method using a flexible gastroscope and a percutaneous endoscopic gastrostomy (PEG) set is described. This overcomes a number of problems and complications which may be encountered when using a rigid endoscope.
Luc's abscess - a rare complication of middle-ear infection
Authors: Knappe M. V. , Gregor R. T. 
Published: November 2007

AbstractA case of subperiosteal temporal abscess of otitic origin is presented. This is an unusual complication of otitis media. The pathogenesis of Luc's abscess is different from other extracranial complications of middle-ear infections in that it is notassociated with mastoid infection which results in subperiosteal pus formation. Based on our experience and the reports from the turn of the century. we present the presumptive pathogenesis and clinical features. We contend that these patients run an unexpectedly benign course, and require concomitantly more conservative treatment than other otitic abscesses.
Revision myringoplasty
Authors: Berger Gilead , Ophir Dov , Berco Eliezer , Sadé Jacob 
Published: November 2007

AbstractThis retrospective study was undertaken to review the short- and long-term results of 70 revision and 16 re-revision myringoplasty operations. Of the former, 43 cases (61.4 per cent) had initial success, six weeks following surgery. The leading causes of immediate failure (27 cases) were associated with a complete no- take of thegraft, infection with graft necrosis and poor anterior adaptation of the graft in decreasing order. Six out of the 43 patients developed late re-perforations during the follow-up period, thus reducing the success rate of revision myringoplasty to 52.8 per cent. Late re-perforations were attributed to insidious atrophy of the tympanic membrane or episodes of acute otitis media. Sixteen patients underwent re-revision myringoplasty and their success rate was 62.5 per cent. The overall success rate of revision and re-revision myringoplasty was 54.7 per cent. It has been concluded that results of revision myringoplastywere independent of patients' age, location and size of perforation and the seniority of the surgeon.
The evaluation of salivary gland tumours using proliferating cell nuclear antigen
Authors: Trendell-Smith N. J. , Oates J. , Crocker J. 
Published: November 2007

AbstractIn order to assess its discriminating and prognostic value, we studied the immunoreactivity for proliferating cell nuclear antigen (PCNA) in tissue from 52 human salivary gland tumours using the murine monoclonal antibody PC10.The PCNA percentage count, namely, the average number of positive nuclei counted per 100 randomly selected tumour cells was recorded for each tumour. Anaplastic carcinoma was used as a positive control and histologically ‘normal’ salivary gland and tonsil served as a negative control.A PCNA count of 30 per cent was postulated to predict malignancy within a given salivary gland tumour i.e. a PCNA count of 30 per cent or above would indicate malignant potential. This gave a sensitivity of 96.9 per cent and a specificity of 95.2 per cent and a positive predictive value of determining malignancy of 96.8 per cent.We conclude that PCNA immunoreactivity is useful in discriminating between benign and malignant salivary gland tumours and that it may have prognostic value in this diverse group of neoplasms.
Aspergillus mastoiditis in a patient with acquired immunodeficiency syndrome
Authors: Yates P. D. , Upile T. , Axon P. R. , de Carpentier J. 
Published: November 2007

AbstractWe present the case history of a patient who was severely immunocompromised due to infection with the human immunodeficiency virus (HIV), and who subsequently developed acute mastoiditis due to Aspergillus fumigatus. Fungal otomastoiditis is a rarely reported complication of HIV infection. A high index of suspicion is required in these patients to facilitate early diagnosis and appropriate therapy.