bluuebunny/crossref_metadata_2025_split huggingface dataset:
Assessing the Job Satisfaction of Some Physicians in Rwanda and the Associated Factors
Authors: Kubwimana L. , Hakizimana J.B.A. , Ishimwe N.C. , Iradukunda G.I. , Nzisabira J. , Shimelash N. , Wong R. 
Published: April 2024

Background: Previous studies have shown poor job satisfaction is a major reason causing physicians to leave their jobs. Poor job satisfaction among physicians can also affect patient health outcomes and discourage young students from pursuing a medical career. This study assessed the level of physician job satisfaction in Rwanda and the associated factors.
Methods: This was a descriptive cross- sectional study. An online survey was conducted to assess the level of physician job satisfaction using the Physician Worklife Survey (PWS) tool. Our sample size was 189. The tool has 41 Likert scale 5-point statements divided into ten domains. Job satisfaction was classified as low if the average survey score was less than 3. Ethical approval was obtained from the University of Global Health Equity IRB committee (Reference no: 0156).
Results: Out of 100 respondents who filled the tool, 50% reported poor job satisfaction. The four domains with the most reported poor satisfaction were related to low income (87.6%), lack of personal time (76.8%), dissatisfaction with work (75.5%), and lack of resources at the workplace (74.5%). Other causes include poor infrastructure, lack of education opportunities, and ignored physicians’ rights. Physicians who were married, specialists, had more than two years of experience and had a second job had better satisfaction levels.
Conclusion: Overall, satisfaction among physicians in Rwanda is low. The factors significantly associated with lower satisfaction were salaries, workloads, and resources. The findings suggest that addressing financial incentives, workloads, and resources may be effective in elevating physician job satisfaction in Rwanda.
Diagnostic Accuracy of Antigen-Based Rapid Test during the Fourth Wave of COVID-19 in Edo State, Nigeria
Authors: Oko-oboh A.G. , Iruobe L. , Osaigbovo I.I. , Obaseki E.D. 
Published: April 2024

Background: Since the use of rapid test kits for diagnosis of COVID-19, diagnostic accuracy has been of concern, particularly in resource- limited settings. This study assessed diagnostic accuracy of Abbot Panbio antigen-based rapid diagnostic test (RDT) for COVID-19 using polymerase chain reaction (PCR) as the gold standard in Edo State, Nigeria.
Methodology: We conducted a descriptive cross-sectional study during the 4th wave of the pandemic in Edo State from January 5 – February 4th, 2022. Nasopharyngeal and oropharyngeal swabs were collected from 240 consenting participants at 10 sample collection sites. The index test (RDT) and gold standard test (real-time reverse transcription PCR) were performed simultaneously. Sensitivity, specificity, predictive values, and ROC analysis were conducted on the RDT compared to RT-PCR using SPSS version 26.0 software.
Results: Thirty-six (15.0%) participants tested positive on RDT and 34 (14.2%) tested positive on PCR. RDT had a sensitivity of 73.5% (95% CI: 66.0–81.0) and specificity of 94.7% (95% CI: 91.6-97.8) with a positive predictive value of 69.4% (95% CI: 55.8-80.7), and negative predictive value of 95.6% (95% CI: 91.8-98.0). The area under the curve (AUC) of the ROC for the RDT against PCR was 84.1% (75.1% - 93.1%).
Conclusion: The diagnostic accuracy of the Panbio rapid antigen test for SARSCoV-2 was below WHO standards. However, they remain useful tools for continued surveillance of the disease. Rigorous evaluations combining the results of rapid antigen tests with other clinical information would prove useful for prompt diagnosis and surveillance of COVID-19 in Nigeria.
Derived $F$-zips
Authors: Yaylali Can 
Published: April 2024

We define derived versions of $F$-zips and associate a derived $F$-zip to any proper, smooth morphism of schemes in positive characteristic. We analyze the stack of derived $F$-zips and certain substacks. We make a connection to the classical theory and look at problems that arise when trying to generalize the theory to derived $G$-zips and derived $F$-zips associated to lci morphisms. As an application, we look at Enriques-surfaces and analyze the geometry of the moduli stack of Enriques-surfaces via the associated derived $F$-zips. As there are Enriques-surfaces in characteristic $2$ with non-degenerate Hodge-de Rham spectral sequence, this gives a new approach, which could previously not be obtained by the classical theory of $F$-zips.Comment: 72 pages. Final version
INTERNALISASI NILAI LOLO TANANAN DAN LOLO PATUOAN : PENINGKATAN EKONOMI ANGGOTA CREDIT UNION SAUAN SIBARRUNG
Authors: Randa Fransiskus , Pasoloran Oktavianus , Bottong Yuliaus 
Published: April 2024

Penelitian ini bertujan untuk menginternalisasi falsafah dan nilai budaya dalam upaya meningkatkan ekonomi anggota koperasi sebagai bagian dari proses reaktualisasi nilai-nilai budaya lokal suatu daerah. Penelitian ini menggunakan pendekatan kualitatif dengan metode etnografi inkulturasi dengan falsafah lolo tananan dan dalam mengelola usaha sebagai alat analisis. Pengumpulan data dilalukan melalui wawancara yang mendalam dengan beberapa informan kunci, observasi lapangan dan pengumpulan artefak budaya di lapangan. Penelitian dilakukan pada koperasi Credit Uniom Sauan Sibarrung yang mencoba mengangkat nilai-nilai lokal dalam mengelola organisasi sebagai landasan operasional kegiatan. Pemaknaan terhadap falsafah lolo tananan dan lolo patuan dalam pengelolaan CU Sauan Sibarrung adalah upaya untuk memingkatkan ekonomi anggota dengan pemberdayaan pemeliharaan sumber daya alam yang bernilai dengan menematkan tanaman dan peternakan secara holistik sebagai bagian yang tidak terpisahkan dari kehidupan masyarakat toraja. Hal itu diinternalisasi melalui program pemberdayaan anggota pada peternakan, peranian dan komunitas kopi. Semua program tersebut mengarah pada peningaktan ekonomi anggota CU dengan pemeliharaan tanaman dan ternak secara berkelanjutan dan menghindari eksploitasi.
STRATEGI PENJUALAN BAHAN BAKAR MINYAK (BBM) PADA PERTAMINI YOGA DI KECAMATAN RANTEPAO KABUPATEN TORAJA UTARA
Authors: Randa Windi 
Published: April 2024

Penelitian ini bertujuan untuk mengetahui Strategi Penjualan Bahan Bakar Minyak (BBM) pada Pertamini Yoga di Kecamatan Rantepao, Kabupaten Toraja utara. Rumusan Masalah pada penelitian ini adalah Strategi Penjualan Bahan Bakar Minyak (BBM) pada Pertamini Yoga di Kecamatan Rantepao, Kabupaten Toraja Utara. Persoalan penelitian ini adalah bagaimana Strategi Penjualan Bahan Bakar Minyak (BBM) pada Pertamini Yoga di Kecamatan Rantepao, Kabupaten Toraja Utara. Penelitian ini menggunakan penelitian Deskriptif Kualitatif dengan teknik pengumpulan data yaitu secara observasi dan wawancara. Populasi yang digunakan adalah para konsumen yang datang mengisi bahan bakar di Pertamini Yoga serta pemilik Pertamini Yoga. Strategi penjualan yang digunakan dalam penelitian ini yaitu terdapat 4 strategi diantaranya: strategi produk, strategi harga, strategi pelayanan dan strategi tempat. Hasil penelitian menyatakan bahwa minat masyarakat terhadap pertamini Yoga dipengaruhi oleh kwalitas produk, penentuan harga, pelayanan yang baik serta kemudahan aksesnya.
Volver a creer
Authors: Minaudo Carla 
Published: April 2024

Ante todo, queremos agradecer a los lectores de Dermatología Argentina porque hemos tenido un fructífero 2023. Los comentarios en relación a los trabajos publicados son verdaderamente alentadores. Contamos con muchos seguidores locales e internacionales, ¡y vamos por más!
Como es habitual, por concurso, se han designado cuatro nuevos integrantes del Comité de Redacción que demostraron tener una formación de alto nivel, interés en la actualización y la investigación científicas, además de voluntad para participar, corregir y mejorar nuestras publicaciones.
En una realidad adversa para la medicina como la que estamos viviendo, encontrar dermatólogos interesados en el trabajo académico resulta sorprendente y esperanzador. Felicitamos a los seleccionados, y despedimos con mucho agradecimiento y afecto a los excelentes correctores salientes.
El desafío actual es impulsar el desarrollo de más artículos originales, de investigación y de educación médica.
Creemos que todavía estamos lejos de alcanzar el real potencial que los dermatólogos argentinos tenemos, el cual se basa en una historia de grandes figuras, cuyos valores y logros tienen que proyectarse, y las nuevas generaciones retomarlos para llevarlos aún más lejos.
Pústulas estériles que asientan sobre base eritematoedematosa
Authors: Calle Juan Francisco Jácome , Rufino Alejandra Duprez , Jofre Diego , Barbarulo Ana 
Published: April 2024

Una paciente de 73 años, con antecedentes de diabetes mellitus tipo 2, hipertensión arterial, hipotiroidismo, insuficiencia cardíaca, dislipemia y obesidad, medicada con enalapril, metformina y levotiroxina, concurrió al Servicio de Dermatología por dermatosis pruriginosa generalizada, de 48 horas de evolución, posterior al inicio del tratamiento con amoxicilina/ácido clavulánico, en guardia externa, por presunta úlcera infectada en el tercio distal de la pierna derecha.
Al examen físico presentaba pústulas no foliculares, sobre base eritematoedematosa y fina escama en superficie, localizadas en tronco, axilas y extremidades.
El laboratorio informó: glóbulos blancos de 10.000mm3 con predominio neutrofílico, glucemia de 226 mg/dl, PCR de 20 mg/L, VSG de 30 mm/h; el resto del laboratorio, ecografía abdominal y radiografía de tórax se encontraban dentro de parámetros normales.
Anatomía patológica: espongiosis; acúmulo de neutrófilos sobre capa cornea. Pequeña ampolla con pared disgregada y vacía, moderado infiltrado inflamatorio linfocitario en banda localizado en dermis superficial, perivascular y perianexial. Capilares dérmicos dilatados.
Decoding Public Policy Making: Unraveling the Variables and Analytical Questions for Systematic, Comprehensive Analysis
Authors: Alswaiti Lina 
Published: April 2024

Purpose: Government employees, like persons in the private sector, spend a lot of their time in public service. Consequently, employee satisfaction is essential for safeguarding long-term effectiveness and efficiency in both private and public sector organizations. Creating satisfactory working environments improves employees’ work-life balance, thus higher satisfaction levels. Every year, job satisfaction levels are measured throughout all the UAE public sector institutes. This is done through a survey sent by the Dubai Government Excellence Program (DGEP) to the employees every year. With the United Arab Emirates being heralded as one of the leading countries to create ideal work environments for employees, this study aims at determining the underlying factors that affect employee satisfaction in Dubai Police traffic department.
Methodology: The study adopted descriptive research design. The research applied a purposive simple random sampling technique and probabilistic sampling technique. Data was collected on Dubai police traffic department employees. A quantitative and qualitative data analysis was conducted for the current research based on the collected data from the questionnaires circulated within the employees of police traffic department. Data were then analyzed using the Statistical Package for Social Sciences (SPSS-15) for statistical analysis. The results were presented in form of tables.
Findings: While the socio-demographic factors could be considered factors explaining job satisfaction, age and marital status are the only factors that strongly explain the relationship due to their significant result. Additionally, for the nine environmental factors, using factor analysis to determine variables that strongly explain the dependent variables, the variable under “my work directly contributes towards organization’s goals” efficiently explains the status of job satisfaction. Furthermore, execution of mandates informed by the ability of the company to address public complaints and safe work environment influences job satisfaction levels.
Unique Contribution to Theory, Practice and Policy: Although salary and work directly contribute towards an organization’s goals, companies can ensure that job levels are acquired in the right way. This way, the organization can efficiently address public complaints and promote a safe and healthy working environment. , these findings will inform further studies on behavioral management and workplace productivity in organizations.
Molecular Docking Investigation of Dioscorea alata Compounds Binding to CCKBR, CHRM3, CHRM5, and H2R for Gastric Ulcer Treatment
Authors: Makiyah Sri Nabawiyati Nurul , Usman Sherly , Ahkam Ahmad Hafidul 
Published: April 2024

Gastric ulcer is a pathological condition characterized by damage to the mucosal and submucosal tissue layers of the stomach. The main proteins targeted in the treatment of gastric ulcers are CCKBR, CHRM3, CHRM5, and H2R because of their roles in the regulation of gastric acid secretion. Dioscorea alata (DA) is known to contain various active compounds with high sapogenin, diosgenin, and dioscorin content, in addition to its carbohydrate content. We investigated the potential of DA compounds to bind to these proteins in silico. Compound and protein structures were retrieved from PubChem (https://pubchem.ncbi.nlm.nih.gov), ChemSpider (http://www.chemspider.com), and the RCSB PDB (https://rcsb.org). Proteins and compounds are prepared first, and then docked to obtain the interactions that might form, and finally visualized to observe the interactions that have been constructed. The results showed that diosgenin and prosapogenin have potential as inhibitors of CCKBR and CHRM5, and diosgenin and dimethyl batatasin IV have potential as inhibitors of CHRM3 and H2R. We conclude that diosgenin, prosapogenin, and dimethyl batatasin IV in DA compounds have the potential to inhibit CCKBR, CHRM3, CHRM5, and H2R for gastric ulcer treatment. It is necessary to further study the effect of Dioscorea alata in vitro through a gastric ulcer model study.
HIGHLIGHTS

Dioscorea alata (DA) is known to contain various active compounds with high sapogenin, diosgenin, and dioscorin content in addition to its carbohydrate content
Gastritis (gastric ulcer) is a pathological condition characterized by damage to the mucosal and sub-mucosal tissue layers of the stomach. The main proteins targeted in the treatment of gastric ulcers are CCKBR, CHRM3, CHRM5, and H2R because of their roles in the regulation of gastric acid secretion
We performed an in-silico study to investigate the potential of DA compounds to inhibit these proteins. Compound and protein structures were retrieved from PubChem, ChemSpider, and the RCSB PDB. Proteins were prepared with Swiss PDB viewer v. 4.10. Compounds were prepared with Open Babel in Cytoscape v.3.9.1. Docking was done with AutoDock Vina in PyRx v.0.9.7. Visualization was done with Discovery Studio v. 19.1
We determined that several DA compounds have the potential to act as inhibitors of CCKBR, CHRM3, CHRM5, and H2R by reviewing the predicted binding energy, competitive properties based on literature studies and the bioactivity and molecular docking analysis. The results of this study are expected to be the basis for further gastric ulcer treatment research

GRAPHICAL ABSTRACT
Physical and Chemical Characterization of Granules from 70 % Ethanol Extract of Ganitri Leaves (Eleocarpus serratus L.) using Wet Granulation Method as An Anti-Osteoporosis
Authors: Widyowati Retno , Sari Romandani Puspita , Retnowati Dini , Sholikhah Irawati , Pratama Rizki Rahmadi 
Published: April 2024

Elaeocarpus serratus L. leaves have been used as an antiosteoporosis treatment and it contains active compounds such as quercetin, rutin, and myricetin. The pre-formulation study was done by making granules from 70 % ethanol extract of this plant through the wet granulation method. These granules were determined by physical characteristics including organoleptic, flow properties, real and incompressible specific gravity, moisture, particle size distribution, and chemical characteristics including flavonoid content. The organoleptic result showed that all formulas had a strong characteristic odor and a slightly bitter taste. Formula A had a dark brown color, while formulas B and C were whitish brown. Based on the results of the flow properties test, all formulas had good flow properties because they had gone through the granulation process. The compressibility index, Hausner ratio, and % moisture content displayed that all formulas met the requirements and had almost the same value. In the assay process, the average % w/w content of formula A was 0.68 ± 0.017 %, formula B was 0.66 ± 0.044 %, and formula C was 0.16 ± 0.006 %. The most optimum formula was formula C with whitish brown color, slightly bitter taste, and strong odor, 10.90 ± 0.000 g/s of flow rate, 25.41 ± 0.000 ° of angle, 4.36 ± 0.214 % of moisture content, 13.80 % compressibility index, 1.1601 of Hausner ratio, 1772.04 µm of particle average distribution, and 0.66 ± 0.044 % w/w of percent routine flavonoid content.
HIGHLIGHTS

This study aims to determine the characteristics of granules from 70 % ethanol extract of ganitri leaves (Elaeocarpus serratus), the optimal formula to make granule preparations with active ingredients of ganitri leaves, and the levels of flavonoids using the spectrophotometer method. It also determined the characteristic physics of granule preparations including flow properties, organoleptic, moisture, particle size distribution, and real and incompressible specific gravity.

GRAPHICAL ABSTRACT
The Combination of Hvsr and Masw Methods with Landsat 8 Imagery to Assess the Changing Shoreline along the Coastal Area of Central Bengkulu
Authors: Farid Muhammad , Hadi Arif Ismul , Refrizon Refrizon , Suhartoyo Hery , Litman Litman , Fadli Darmawan Ikhlas , Putriani Eli 
Published: April 2024

The Central Bengkulu Regency possesses a coastline measuring 21.8 km, situated in direct proximity to the Indian Ocean. The heightened wave and ocean current dynamics possess the capacity to induce detrimental effects in the form of coastal abrasion along the coastline. This study conducted an examination of the rate of shoreline changes resulting from coastal abrasion in Central Bengkulu Regency, Bengkulu, Indonesia. Horizontal-to-vertical spectral ratio (HVSR) analysis, multichannel analysis of surface waves (MASW), and Landsat-8 remote sensing were all used in the current investigation. The project gets started with conducting field investigations and measurements of geophysical techniques, including the collection of Landsat-8 satellite imagery spanning the period from 1990 to 2020. Additionally, an examination was conducted on the rate at which the shoreline undergoes changes in velocity. In order to determine the increase in change that occurs along coastlines over a period of several decades, a study was carried out during which Landsat-8 satellite images were analyzed. This study investigates the application of the HVSR technique for assessing the seismic vulnerability of the ground and, additionally, the MASW technique for measuring the shear wave velocity of the coastline’s soil. Both of these methodologies are compared and contrasted with one another in this research. The findings indicated that the mean pace of coastline change in Central Bengkulu Regency was 1.5 m/yr, with the maximum velocity recorded at 4.1 m/yr. This high velocity of shoreline change is correlated with the Vs30 value of MASW measurement and Kg of HVSR measurement, where the subsurface soil structure along the coast of Central Bengkulu Regency from Vs30 measurement shows that it is dominated by stiff soil structure that is susceptible to erosion. Outcomes from the study can inform decision-making processes about safeguards and preventative measures to prevent further coastal degradation.
HIGHLIGHTS

In this paper, we present a framework using application passive and active seismic method with Landsat 8 for knowing the changing of shoreline coastal area in Central Bengkulu Indonesia
This study demonstrated that the high velocity of the shifting shoreline is correlated with Vs30 and Kg values
The subsurface soil structure is predominantly composed of stiff soil, and the changing shoreline starts at 1.5 mm/yr, which makes the coast of Central Bengkulu vulnerable to erosion

GRAPHICAL ABSTRACT
Biofilm Production and Porin Permeability Activity in Clinical Isolates of Ciprofloxacin-Resistant Klebsiella pneumoniae in the Tertiary Hospital in Purwokerto, Indonesia
Authors: Sulistiyawati Indah , Siswandari Wahyu , Joko Wahyono Daniel 
Published: April 2024

World Health Organization reports that the current use of ciprofloxacin as a broad-spectrum antibiotic shows a pattern of high bacterial resistance in many countries. Klebsiella pneumoniae is known as a Gram-negative bacterium that most often causes infection and is resistant to antibiotics. This study aimed to find patterns of resistance mechanisms based on biofilm production and porin permeability activity in K. pneumoniae clinical specimens from patients at RSUD Prof. Dr Margono Soekardjo Purwokerto, Indonesia. Several isolates of ciprofloxacin-resistant K. pneumoniae were isolated from clinical specimens of blood, sputum, urine, pus, stool and pleural fluid from August to October 2022. Identification and sensitivity testing of K. pneumoniae to ciprofloxacin were performed using Vitek® 2 Compact. A test for biofilm production is carried out by measuring optical density (OD) with a microplate at a wavelength of 630 nm. The porin permeability activity was determined using the value of the minimum inhibitory concentration (MIC) by the LC-MS spectrophotometry method at a wavelength of 630 nm. The results showed that 72 (47 %) isolates were resistant to ciprofloxacin. Among them, 41.3 % (24/58) of ciprofloxacin-resistant K. pneumoniae were able to produce strong biofilm. Porin permeability is indicated by MIC values of 1, 2 and 4 mg/L with bacterial cell counts of 32×106, 19×106 and 34×106 CFU/mL, respectively. This number decreased from the initial control with a bacterial cell count of 10.15×107 CFU/mL. Analysis of the correlation between the significance of biofilm production and the number of bacterial cells indicated that biofilm formation was related to the number of bacterial cells (R = 0.628, p ≤ 0.05). In conclusion, the resistance mechanism of ciprofloxacin-resistant K. pneumoniae involves biofilm production and decreased porin permeability activity.
HIGHLIGHTS

Major resistance mechanisms in pneumoniae decreased cell permeability from porin activity and biofilm formation
Bacterial outer membrane permeability to antimicrobial substances influences inherent resistance. Bacteria produce biofilm to increase their resistance to antibiotics. Porins are non-specific diffusion transport proteins that play a part in the antibiotic resistance process
The evolutionary development in the case of antibiotic resistance has an impact on the emergence of understanding in new perspective patterns on how to overcome health problems related to antibiotic resistance

GRAPHICAL ABSTRACT
Raíces cuadráticas - métodos alternativos:
Authors: Jungnikel Matamoros Luis Damián , Loor Solarte Mishelle Stephanie 
Published: April 2024

La metodología tradicional para la enseñanza de resolución de ecuaciones cuadráticas, es decir en su factorización, incluyen la memorización de ecuaciones y de algoritmos que, aunque han facilitado hasta hoy encontrar los resultados de manera eficiente, limitan notablemente la creatividad que nos brindan las matemáticas. En este breve artículo, usted encontrará tres propuestas de algoritmos y formas alternativas de la ecuación general, que pueden ser implementadas en la enseñanza del día a día, facilitando aún más la resolución de dichas parábolas. El primer método es una variante de la ya popular forma usada por el Dr. Po-Shen Loh, mientras que la segunda y tercera son aproximaciones de la famosa fórmula general, simplificándola significativamente, para hacer más sencilla su aplicación.