bluuebunny/crossref_metadata_2025_split huggingface dataset:
Publication barriers and facilitators of Cochrane authors in sub‐Saharan Africa: A mixed‐methods study
Authors: Kallon Idriss I. , Young Taryn , MacDonald Tonya A. , Schoonees Anel , Oliver Joy , Arikpo Dachi I. , Durão Solange , Effa Emmanuel , Hohlfeld Ameer S.‐J. , Kredo Tamara , Wiysonge Charles S. , Mbuagbaw Lawrence 
Published: April 2024

AbstractBackgroundWell‐conducted systematic reviews contribute to informing clinical practice and public health guidelines. Between 2008 and 2018 Cochrane authors in sub‐Saharan Africa were publishing progressively fewer Cochrane Reviews, compared to non‐Cochrane reviews. The objective of this study was to determine what motivated trained Cochrane authors in sub‐Saharan Africa to conduct and publish non‐Cochrane reviews over Cochrane Reviews.MethodsWe conducted a mixed‐methods exploratory sequential study. We purposely selected 12 authors, who had published at least one Cochrane‐ and one non‐Cochrane review, for in‐depth, semi‐structured interviews. We manually coded and analysed the qualitative data using Grounded Theory approach and used the results to inform the survey questions. Subsequently we surveyed 60 authors with similar publishing experience. We analysed the quantitative data using descriptive and inferential statistics.ResultsFacilitators to publish with Cochrane were a high‐impact factor, rigorous research, and visibility. From barriers, the main categories were protracted time to complete Cochrane Reviews, complex title registration process, and inconsistencies between Cochrane Review groups regarding editorial practices. From the survey, authors confirmed rigorous research and reviewing process (84%), high impact factor (77%), and good mentorship (73%). The major barriers included Cochrane's long reviewing process (70%) and Cochrane's complicated title registration (50%). Authors with publishing experience in the previous 10 years at <95 percentile of systematic review publications, there was no significant difference between the medians for publishing with Cochrane (1) and non‐Cochrane (0) reviews, p = 0.06. Similarly, for those with publishing experience of ≥95 percentile of systematic review publication there was no significant difference between the medians for publishing with Cochrane (4) and non‐Cochrane (6), p = 0.344.ConclusionAuthors considered the visibility and relevance of Cochrane research as a trade‐off point. They continued publishing with Cochrane despite the barriers that they encountered. However, the concerns raised by many authors are worth addressing.
Novel ethylenediamine‐β‐cyclodextrin grafted membranes for the chiral separation of mandelic acid and its derivatives
Authors: Zhou Junjie , Wei Yongming , Wu Jiaojie , Li Shuqin , Xu Zhenliang , Peng Yangfeng 
Published: April 2024

AbstractIn the present study, flat cellulose acetate ultrafiltration membranes were prepared first by nonsolvent induced phase separation method. Then chiral membranes for separating the enantiomers were prepared by grafting the ultrafiltration membranes using ethylenediamine‐β‐cyclodextrin as the chiral selector and epichlorohydrin as the spacer arm. The pure water permeability of the ultrafiltration membrane was around 115 L·m−2·h−1·bar−1. The properties of the chiral membranes were characterized using infrared spectroscopy (ATR‐FTIR), X‐ray photoelectron spectroscopy (XPS), and scanning electron microscopy (SEM). The chiral membrane performance in enantiomer separation was evaluated with racemates, such as mandelic acid (MA), 2‐chloromandelic acid (2‐ClMA), 4‐chloromandelic acid (4‐ClMA), and methyl mandelate (MM). The influence of feed concentration on the separation efficiency was also investigated. The results indicated that the enantiomeric excess percentages (e.e%) of the racemic mixtures for these four chiral compounds were up to 31.8%, 25.4%, 17.8%, and 32.6%, respectively. The binding free energy of the chiral selector with the (S)‐enantiomer calculated by molecular dynamics simulations was stronger than that with the (R)‐enantiomer, which was consistent with the experimental results (higher concentration of (R)‐enantiomer in the permeate). This supports the affinity absorption‐separation mechanism.
Preparation of amino acid chiral ionic liquid and visual chiral recognition of glutamine and phenylalanine enantiomers
Authors: Dong Luzheng , Wu Jun , Zhu Xiashi 
Published: April 2024

AbstractIn this paper, the amino acid chiral ionic liquid (AACIL) was prepared with L‐phenylalanine and imidazole. It was characterized by CD, FT‐IR, 1H NMR, and 13C NMR spectrum. The chiral recognition sensor was constructed with AACIL and Cu(II), which exhibited different chiral visual responses (solubility or color difference) to the enantiomers of glutamine (Gln) and phenylalanine (Phe). The effects of solvent, pH, time, temperature, metal ions, and other amino acids on visual chiral recognition were optimized. The minimum concentrations of Gln and Phe for visual chiral recognition were 0.20 mg/ml and 0.28 mg/ml, respectively. The mechanism of chiral recognition was investigated by FT‐IR, TEM, SEM, TG, XPS, and CD. The location of the host‐guest inclusion or molecular placement has been conformationally searched based on Gaussian 09 software.
Chemical Bonding, 10Dq Parameter and Superexchange in the Model Compound KNiF3
Authors: Sánchez‐Movellán Inés , Aramburu José Antonio , Moreno Miguel 
Published: April 2024

AbstractThe cubic field splitting parameter, 10Dq, plays a central role in the ligand field theory on insulating transition metal compounds. Experimental data obtained in the last 50 years prove that 10Dq is highly dependent on changes of the metal‐ligand distance, R, induced by chemical or applied pressures. Despite this fact has important consequences on optical and magnetic properties of such compounds, its actual origin is still controversial. Seeking to clarify that crucial issue, this work is focused on KNiF3, a reference system among insulating transition metal compounds. By means of first principles calculations we show that, contrary to what is usually thought, the R‐dependence of 10Dq arises neither from the crystal field contribution nor from the covalent admixture of 3d(Ni) with valence 2p(F) orbitals. Indeed, we prove that it is mainly due to the residual covalency with deep 2s(F) orbitals, highly sensitive to R variations. As a salient feature the present calculations show that the 3d–2pσ and 3d–2pπ admixtures raise practically equal the energy of antibonding eg and t2g orbitals of NiF64− units in KNiF3 thus leading to a null contribution to 10Dq. This conclusion is not significantly altered when considering the change of covalency on passing from the ground state 3A2(t2g6eg2) to the excited state 3T2(t2g5eg3). The different influence of chemical bonding on the superexchange constant, J, and 10Dq is also discussed in a second step. It is pointed out that the strong dependence of J upon R can hardly be explained through the behavior of the 3d–2pσ covalency derived for a single NiF64− unit. For the sake of clarity, the meaning of 10Dq is also briefly analyzed.
Evaluating Suicide Risk Stratification in Outpatient Settings: A Vignette‐Based Approach
Authors: Litschi Melissa A. , Lancaster Steven L. , Linkh David J. , Renno Stephanie , Neal‐Walden Tracy A. , Lawless Claire E. , Breetz Alisa A. 
Published: April 2024

ABSTRACTSuicide risk assessment and stratification are a key suicide prevention strategy in mental health care systems that treat military service members and veterans. The aim of the current mixed‐method project was to address a gap in our knowledge as to how therapists make these important clinical decisions. This manuscript reports the results of a project during which six vignettes were developed reflecting varying levels of risk according to the Rocky Mountain MIRECC Risk Stratification Table. Mental health therapists were asked to evaluate the risk level of each vignette, determine a treatment disposition, and provide justification for their ratings. The results of the study indicate that therapists can reliably evaluate risk, but that treatment planning tended to be based more on vignette‐specific factors than essential features of the risk model. The qualitative findings revealed variations in the definition and perception of foundational concepts, suggesting a need for further research and training in these domains. Overall, the results support the use of vignettes as a method to assess clinical decision‐making and provide several areas for further training and research.
Calcium Doped NASICON Electrolyte with Graphite Coating for Stable All‐solid‐state Sodium Metal Batteries
Authors: Jia Jing , Liu Tinghu , Li Yunming , Yang Jing , He Hao , Zhu Xiaoning , Yao Xiayin 
Published: April 2024

AbstractAll‐solid‐state sodium metal batteries face the challenges of low ionic conductivity of solid electrolytes and poor wettability towards metallic Na anode. Herein, Na3Zr2Si2PO12 solid electrolyte is doped with Ca2+, obtaining a high ionic conductivity of 2.09×10−3 S cm−1 with low electronic conductivity of 1.43×10−8 S cm−1 at room temperature, which could accelerate Na+ transportation and suppress sodium dendrite growth. Meanwhile, a graphite‐based interface layer is coated on Na3.4Zr1.8Ca0.2Si2PO12 (Na3.4Zr1.8Ca0.2Si2PO12‐G) in order to improve the solid‐solid contact between solid electrolyte and Na anode, realizing a uniform current distribution and smooth Na metal plating/stripping, and thus achieving a triple higher critical current density of 3.5 mA cm−2 compared with that of Na3.4Zr1.8Ca0.2Si2PO12. In addition, the assembled Na3V2(PO4)3/Na3.4Zr1.8Ca0.2Si2PO12‐G/Na all‐solid‐state battery exhibits excellent electrochemical performances with a reversible capacity of 81.47 mAh g−1 at 1 C and capacity retention of 97.75 % after 500 cycles.
Carbon‐Supported Ru‐Ni and Ru‐W Catalysts for the Transformation of Hydroxyacetone and Saccharides into Glycol‐Derived Primary Amines
Authors: Boulos Joseph , Goc Firat , Vandenbrouck Tom , Perret Noémie , Dhainaut Jérémy , Royer Sébastien , Rataboul Franck 
Published: April 2024

AbstractNitrogen‐containing molecules are used for the synthesis of polymers, surfactants, agrochemicals, and dyes. In the context of green chemistry, it is important to form such compounds from bioresource. Short‐chain primary amines are of interest for the polymer industry, like 2‐aminopropanol, 1‐aminopropan‐2‐ol, and 1,2‐diaminopropane. These amines can be formed through the amination of oxygenated substrates, preferably in aqueous phase. This is possible with heterogeneous catalysts, however, effective systems that allow reactions under mild conditions are lacking. We report an efficient catalyst Ru−Ni/AC for the reductive amination of hydroxyacetone into 2‐aminopropanol. The catalyst has been reused during 3 cycles demonstrating a good stability. As a prospective study, extension to the reactivity of (poly)carbohydrates has been realized. Despite a lesser efficiency, 2‐aminopropanol (9 % yield of amines) has been formed from fructose, the first example from a carbohydrate. This was possible using a 7.5 %Ru‐36 %WxC/AC catalyst, composition allowing a one‐pot retro‐aldol cleavage into hydroxyacetone and reductive amination. The transformation of cellulose through sequential reactions with a combination of 30 %W2C/AC and 7.5 %Ru‐36 %WxC/AC system gave 2 % of 2‐aminopropanol, corresponding to the first example of the formation of this amine from cellulose with heterogeneous catalysts.
Carboxylate Bridged Binuclear Cobalt(II) Complexes Catalyze the Hydrolysis of Thiolates to Alcohols
Authors: Chakraborty Anuj Baran , Ganguly Tuhin , Bera Abhijit , Majumdar Amit 
Published: April 2024

AbstractA binuclear Co(II) complex, [Co2(PhBIMP)(μ‐O2CPh)(MeCN)]2+ (1) (PhBIMP is the anion of 2,6‐bis[(bis((N‐1‐methyl‐4,5‐diphenylimidazoylmethyl) amino)methyl]‐4‐methylphenol) catalyzes the hydrolysis of thiolates to the corresponding alcohols/phenols at room temperature. Hydrolysis of 11 different thiolates has been investigated with a catalyst loading of 4–6.7 mol% and with the highest TON values reaching 22. Furthermore, the effects of electron donating and electron withdrawing groups on the bridging benzoate of 1 have been investigated. The intermediates, products, and fate of the catalyst have been identified by mass spectrometric, gas chromatographic and gravimetric methods, and based on that, a mechanism for the catalytic cycle has been proposed.
The prevalence, incidence and management of low back pain with radiating leg pain in Dutch general practice: A population‐based cohort study in the Rijnmond Primary Care Database
Authors: Khorami Ahmad Khoshal , Chiarotto Alessandro , de Schepper Evelien I. T. , Bindels Patrick J. E. , Koes Bart W. , van den Driest Jacoline J. 
Published: April 2024

AbstractBackgroundRadiating leg pain is common in patients with low back pain (LBP). In this study, we aimed to determine the prevalence and incidence of LBP with radiating leg pain in Dutch general practice, and to describe the prescribed medications and requested imaging diagnostics.MethodsThe Rijnmond Primary Care Database containing over 500,000 primary care patients was used to select patients ≥18 years with LBP with radiating leg pain between 2013 and 2021. Data on patient characteristics, LBP episodes, prescribed medication and requested imaging in the first 3 months of an episode was extracted. Descriptive statistics were used to present patient characteristics and diagnostic/therapeutic interventions.ResultsA total of 27,695 patients were included. The total number of LBP with radiating leg pain episodes in these patients was 36,268. In 2021, the incidence and prevalence were 19.1 and 25.7 per 1000 patient years, respectively. In 60% of patients, the episode duration was shorter than 1 month. In 62% of the episodes, patients visited the general practitioner (GP) one to two times. In 59% of the episodes, at least one medication was prescribed, non‐steroidal anti‐inflammatory drugs (NSAIDs) being the most common one (45%). In approximately 11% of the episodes, additional diagnostic imaging was requested.ConclusionLBP with radiating leg pain is common in Dutch general practice patients. About 2/3rd were prescribed pain medications. Dutch request few to none diagnostic imaging for these patients which is in line with clinical practice guidelines.SignificanceIn this new study, we have gained insights into the incidence and prevalence of LBP with radiating leg pain in Dutch general practice. Both remained fairly stable over the study period of 9 years (2013–2021). Overall, the care burden regarding seeking contact with the GPs and the requested diagnostics seem not to be that high. In 62% of the care episodes, there were one or two consultations with the GP, and in 11% of the episodes a diagnostic imaging was requested. Pain medications frequently prescribed (i.e. 2/3rd of the episodes), with NSAIDs being the most common ones.
Laser‐induced graphene formation on recycled woods for green smart furniture
Authors: Nam Han Ku , Choi Jungrak , Jing Tongmei , Yang Dongwook , Lee Younggeun , Kim Young‐Ryeul , Le Truong‐Son Dinh , Kim Byunggi , Yu Liandong , Kim Seung‐Woo , Park Inkyu , Kim Young‐Jin 
Published: April 2024

AbstractIn the pursuit of carbon neutrality policies, the development of eco‐friendly and intelligent furniture commands a significant role. However, the integration of non‐biodegradable electronic components in smart furniture fabrication has led to substantial electronic waste. Here, we report a straightforward approach, the rapid production of Laser‐Induced Graphene (LIG) on medium‐density fiberboard (MDF), a prevalent recycled wood in furniture production. This LIG electrode is crafted with negligible material ablation in ambient air with the aid of femtosecond laser pulses, without requiring any additional materials, showcasing the highest electrical conductivity (2.781 Ω sq−1) among previously reported lignocellulosic materials‐based LIG. The application of this LIG electrode for lighting, heating, and touch sensors displays sufficient performance for smart furniture implementation. For eco‐conscious furniture, LIG‐based human‐machine interfaces are demonstrated on recycled woods for the facile control of smart devices, which will readily enable IoT‐oriented smart sustainable furniture.image
Radioactive iodine therapy improves overall survival outcome in oncocytic carcinoma of the thyroid by reducing death risks from noncancer causes: A competing risk analysis of 4641 patients
Authors: Zhang Kun , Wang Xinyi , Wei Tao , Li Zhihui , Zhu Jingqiang , Chen Ya‐Wen 
Published: April 2024

AbstractBackgroundOncocytic carcinoma of the thyroid (OCA) is an independent type of thyroid cancer. Radioactive iodine (RAI) therapy was frequently administered to OCA patients, but its contribution to improving survival is indefinite.Methods4641 OCA patients from 2000 to 2018 were identified from the Surveillance, Epidemiology, and End Results (SEER) database. Cox proportional hazard regression and competing risk analysis were applied.ResultsTumor size, SEER stage, primary surgery, and neck dissection were prognostic factors for cancer‐specific survival. The results of competing risk analysis demonstrated that age over 55 years dramatically increased non‐OCA death risks. Treatments that improve non‐OCA survival (including total thyroidectomy, RAI therapy, and systemic therapy) should be recommended in OCA patients older than 55 years of age. Neck lymphadenectomy should not be recommended for OCA, since the metastatic lymph node ratio was low (about 3%).ConclusionsRAI therapy can improve survival in OCA by reducing noncancer death risks.
Utilizing MBSE for disposable intravenous infusion set: A case study on systems thinking in medical device industry.
Authors: Mehta Ashish , Jawale Ankita , Khan Mohammed Mehtab , Vidap Akshay , Mangumali Manjunath 
Published: April 2024

AbstractSystems Engineering has demonstrated significant value and has become increasingly necessary. However, this has increased challenges in the quest to build next gen systems tailored to changing customer needs and evolving industry requirements. Many systems engineering practices have evolved catering to these challenges, leading to development of model‐based systems engineering approaches. This paper describes leveraging MBSE and systems thinking application in medical device industry to adapt with changing customer needs, comply with regulatory constraints and advance towards sustainability.
System Of Systems Modeling for Urban Air Mobility Concept
Authors: Singh Dhirendra 
Published: April 2024

AbstractThe exploration of Systems of Systems (SoS) modeling using Model‐Based Systems Engineering (MBSE) is an ongoing area of research, wherein researchers are actively investigating various frameworks and languages suitable for initiating SoS modeling. Urban Air Mobility (UAM) represents a novel approach to urban transportation, integrating multiple systems and stakeholders to enable on‐demand, environment friendly, efficient, and sustainable air travel within cities. International organizations have dedicated significant efforts to develop a comprehensive Concept of Operation (ConOps) for UAM, aiming to define the UAM ecosystem and identify the supporting systems. While previous research was focused on defining the Urban Air System (UAS) using Systems Modeling Language (SysML), there remains a gap in capturing the ConOps for UAM as a System of Systems (SoS) using SysML. This study seeks to address this gap by utilizing the MagicGrid Framework for SoS modeling.
Clinical characteristics of endometrioma with and without dysmenorrhea diagnosed by laparoscopy: A retrospective cohort study in a tertiary center
Authors: Choi Haeryung , Kim Sung Eun , Lee Nae Hyun , Lee Dong‐Yun , Choi DooSeok 
Published: April 2024

AbstractObjectiveClinical characteristics of patients with endometrioma without dysmenorrhea have not been well delineated; our goal was to remedy this issue by performing a retrospective cohort study.MethodsA total of 379 patients who underwent laparoscopic surgery for endometrioma ≥4 cm at a tertiary hospital were included in this retrospective study. Patients were divided into two groups based on the presence of dysmenorrhea at the time of hospital visit; with dysmenorrhea group and without dysmenorrhea group.ResultsPatients without dysmenorrhea comprised 9.5% of all surgically confirmed endometriomas. Significant differences were found in the revised American Society for Reproductive Medicine (rASRM) stage, age at surgery, and bilaterality. Patients with rASRM stage IV were more likely to have dysmenorrhea than were subjects with rASRM stage III (odds ratio (OR), 10.58; 95% confidence interval (CI), 4.63–24.21; P < 0.001). Older patients were less likely to have dysmenorrhea (OR, 0.94; 95% CI, 0.88–1.00; P = 0.045), as were patients with bilateral rather than unilateral endometrioma (OR, 0.36; 95% CI, 0.15–0.82; P = 0.015). No significant differences in cyst size, age at menarche, body mass index (BMI), parity, or history of previous ovarian surgery were found between the two groups.ConclusionPatients without dysmenorrhea comprised 9.5% of endometrioma cases and had less advanced rASRM stage, were older at surgery, and had a higher probability of bilateral than unilateral endometrioma than patients with dysmenorrhea.
Escargot a Snail superfamily member and its multiple roles in Drosophila melanogaster development
Authors: Zambrano‐Tipan Diego , Narváez‐Padilla Verónica , Reynaud Enrique 
Published: April 2024

AbstractThe Snail superfamily of transcription factors plays a crucial role in metazoan development; one of the most important vertebrate members of this family is Snai1 which is orthologous to the Drosophila melanogaster esg gene. This review offers a comprehensive examination of the roles of the esg gene in Drosophila development, covering its expression pattern and downstream targets, and draws parallels between the vertebrate Snai1 family proteins on controlling the epithelial‐to‐mesenchymal transition and esg. This gene regulates stemness, ploidy, and pluripontency. esg is expressed in various tissues during development, including the gut, imaginal discs, and neuroblasts. The functions of the esg include the suppression of differentiation in intestinal stem cells and the preservation of diploidy in imaginal cells. In the nervous system development, esg expression also inhibits neuroblast differentiation, thus regulating the number of neurons and the moment in development of neuronal differentiation. Loss of esg function results in diverse developmental defects, including defects in intestinal stem cell maintenance and differentiation, and alters imaginal disc and nervous system development. Expression levels of esg also play a role in regulating longevity and metabolism in adult stages. This review provides an overview of the current understanding of esg's developmental role, emphasizing cellular and tissue effects that arise from its loss of function. The insights gained may contribute to a better understanding of evolutionary conserved developmental mechanisms and certain metabolic diseases.