bluuebunny/crossref_metadata_2025_split huggingface dataset:
Surface‐methacrylated microcrystalline cellulose bioresins with soybean oil for additive manufacturing via vat photopolymerization
Authors: Parikh Ankit R. , Cortés‐Guzmán Karen P. , Bian Ning , Johnson Rebecca M. , Smaldone Ronald A. , Lu Hongbing , Voit Walter E. 
Published: March 2024

AbstractThe additive manufacturing (AM) industry increasingly looks to differentiate itself by utilizing materials and processes that are green, clean, and sustainable. Biopolymers, bio‐sourced raw materials and light weighting of parts 3D printed with photopolymer resins each represent critical directions for the future of AM. Here, we report a series of bio‐based composite resins with soybean oil derivatives, up to 20% by weight of surface‐methacrylated micro‐crystalline cellulose (MCC) and 60% total bio‐based content for vat photopolymerization based additive manufacturing. The ultimate tensile strengths of the materials were found to increase up to 3X, the Young's moduli increased up to 10X, and the glass transition temperature increased by 11.3°C when compared to the neat resin without surface‐methacrylated MCC as a filler. Working curves and shrinkage factors were used to demonstrate how the surface‐methacrylated MCC causes changes in the dimensions of printed parts, to facilitate development of optimized print parameters based on the UV intensity of the 3D printer being used. These results will allow further development of commercial 3D printable resins with a high concentration of bio‐based fillers that print well and perform on par with conventional resins.
Detection and coverage estimation of purple nutsedge in turf with image classification neural networks
Authors: Jin Xiaojun , Han Kang , Zhao Hua , Wang Yan , Chen Yong , Yu Jialin 
Published: March 2024

AbstractBACKGROUNDAccurate detection of weeds and estimation of their coverage is crucial for implementing precision herbicide applications. Deep learning (DL) techniques are typically used for weed detection and coverage estimation by analyzing information at the pixel or individual plant level, which requires a substantial amount of annotated data for training. This study aims to evaluate the effectiveness of using image‐classification neural networks (NNs) for detecting and estimating weed coverage in bermudagrass turf.RESULTSWeed‐detection NNs, including DenseNet, GoogLeNet and ResNet, exhibited high overall accuracy and F1 scores (≥0.971) throughout the k‐fold cross‐validation. DenseNet outperformed GoogLeNet and ResNet with the highest overall accuracy and F1 scores (0.977). Among the evaluated NNs, DenseNet showed the highest overall accuracy and F1 scores (0.996) in the validation and testing data sets for estimating weed coverage. The inference speed of ResNet was similar to that of GoogLeNet but noticeably faster than DenseNet. ResNet was the most efficient and accurate deep convolution neural network for weed detection and coverage estimation.CONCLUSIONThese results demonstrated that the developed NNs could effectively detect weeds and estimate their coverage in bermudagrass turf, allowing calculation of the herbicide requirements for variable‐rate herbicide applications. The proposed method can be employed in a machine vision‐based autonomous site‐specific spraying system of smart sprayers. © 2024 Society of Chemical Industry.
A three‐way electrolyte with ternary solvents for high‐energy‐density and long‐cycling lithium–sulfur pouch cells
Authors: Li Zheng , Yu Legeng , Bi Chen‐Xi , Li Xi‐Yao , Ma Jin , Chen Xiang , Zhang Xue‐Qiang , Chen Aibing , Chen Haoting , Zhang Zuoru , Fan Li‐Zhen , Li Bo‐Quan , Tang Cheng , Zhang Qiang 
Published: March 2024

AbstractLithium–sulfur (Li–S) batteries promise high‐energy‐density potential to exceed the commercialized lithium‐ion batteries but suffer from limited cycling lifespan due to the side reactions between lithium polysulfides (LiPSs) and Li metal anodes. Herein, a three‐way electrolyte with ternary solvents is proposed to enable high‐energy‐density and long‐cycling Li–S pouch cells. Concretely, ternary solvents composed of 1,2‐dimethoxyethane, di‐isopropyl sulfide, and 1,3,5‐trioxane are employed to guarantee smooth cathode kinetics, inhibit the parasitic reactions, and construct a robust solid electrolyte interphase, respectively. The cycling lifespan of Li–S coin cells with 50 µm Li anodes and 4.0 mg cm−2 sulfur cathodes is prolonged from 88 to 222 cycles using the three‐way electrolyte. Nano‐heterogeneous solvation structure of LiPSs and organic‐rich solid electrolyte interphase are identified to improve the cycling stability of Li metal anodes. Consequently, a 3.0 Ah‐level Li–S pouch cell with the three‐way electrolyte realizes a high energy density of 405 Wh kg−1 and undergoes 27 cycles. This work affords a three‐way electrolyte recipe for suppressing the side reactions of LiPSs and inspires rational electrolyte design for practical high‐energy‐density and long‐cycling Li–S batteries.
lncRNA NORAD alleviates dysfunction of renal proximal tubular epithelial cells during the sepsis‐associated acute kidney injury by modulating the miR‐155‐5p‐PDK1 axis
Authors: Lu Hulin , Chen Yan , Yang Yong , Ding Min , Qiu Fengping 
Published: March 2024

AbstractThe sepsis‐associated acute kidney injury (Sa‐AKI) is closely related to high mortality rates worldwide. Injury to the renal proximal tubular epithelial cells (RPTECs), caused by pathological conditions, is a major cause of acute kidney injury (AKI). The lncRNA NORAD has been reported to be positively associated with kidney cancers. However, the biological roles and underlying mechanisms of NORAD in RPTECs during AKI are still unclear. In this study, we found that NORAD was significantly downregulated in RPTECs from AKI tissues. Overexpression of NORAD alleviated RPTECs injury induced by lipopolysaccharide (LPS). Additionally, glucose metabolism was significantly impaired during AKI, and LPS treatment inhibited glucose metabolism in RPTECs. We demonstrated that NORAD rescued the LPS‐induced inhibition of glucose metabolism in RPTECs. Furthermore, miRNA‐155‐5p was significantly upregulated in RPTECs from AKI. Through bioinformatics analysis, RNA pull‐down, RNA IP, and luciferase assays, we showed that NORAD directly associated with miR‐155‐5p to downregulate its expression. Moreover, overexpression of miR‐155‐5p inhibited glucose metabolism by directly targeting the 3′UTR of the glucose metabolism enzyme, pyruvate dehydrogenase kinase 1 (PDK1). Finally, rescue experiments validated that NORAD's protective effect on RPTECs injury was mediated through modulation of the miR‐155‐5p‐PDK1‐glucose metabolism pathway. In summary, these results reveal that lncRNA NORAD can alleviate RPTECs dysfunction by targeting the miR‐155‐5p‐PDK1 axis, suggesting that NORAD has the potential to contribute to the development of therapeutic approaches against Sa‐AKI.
Effect of oxidation on physicochemical characteristics of thermoplastic canna starch
Authors: Pham Thi Thu Ha , Nguyen Thanh Tung , Nguyen Van Khoi , Nguyen Trung Duc , Pham Thu Trang , Nguyen Thu Huong , Pham Ngoc Anh 
Published: March 2024

AbstractThe effects of oxidation on physicochemical characteristics of thermoplastic canna starch were investigated. Thermoplastic starch (TPS) of native canna starch (CS) and oxidized canna starch (OCS) were prepared with different contents of sodium hypochlorite (1%, 3%, and 5% w/w) and 30 wt% of glycerol as plasticizer. Native starch‐based TPS (NTPS) and oxidized starch‐based TPS (OTPS) samples were tested for physicochemical, morphological, thermal, and mechanical properties. In OCS, the content of carboxyl and carbonyl groups increased with the increase in the content of oxidant, and this contributed to the improvement in CS plasticization efficiency. SEM images indicated that the morphology of OTPS samples was smoother than that of NTPS. The stronger interaction between OCS and plasticizer in OTPS was indicated by FTIR spectra. XRD confirmed that the crystallite type of starch was changed and their decrease in crystallinity is attributed to effects of both oxidation and plasticization. The carbonyl and carboxyl content had a large impact on Tg and ΔHg of OTPS. The higher content of these groups in OCS leads to the lower Tg and the lower ΔHg, which could make the plasticization easier. Due to the better plasticization in OTPS, their mechanical properties and thermal stability were enhanced.
Unveiling geometric and electronic structures of NbSi4−/0 clusters and electron detachments of the anionic cluster: A quantum chemical investigation
Authors: Tran Van Tan 
Published: March 2024

AbstractThis article presents computational insights into the geometric and electronic structures of NbSi4−/0 clusters using density functional theory and the CASSCF/CASPT2 method. The anionic and neutral ground states are identified as the 1A′ and 2A′ states, respectively, within a trigonal bipyramidal isomer where the Nb atom occupies the equatorial position. The adiabatic detachment energy for the transition from the anionic ground state 1A′ to the neutral ground state 2A′ is estimated to be 2.30 eV. Additionally, an evaluation of the vertical detachment energies for transitions to the neutral states 12A′, 12A″, 22A′, 22A″, 32A′, 32A″, and 42A′ yields respective values of 2.42, 2.78, 2.94, 3.34, 3.86, 4.08, and 4.28 eV. These computed electron detachment energies successfully account for all five bands observed in the photoelectron spectrum of the anionic cluster. Furthermore, the Franck–Condon factor simulations reveal extensive vibrational progressions associated with the transition to the neutral ground state 12A′, manifesting as an unresolved broad band at 2.41 eV in the spectrum.
Response of frequency domain in generalized thermoelastic medium under modified Green‐Lindsay with non‐local and two temperature
Authors: Kaushal Sachin , Kumar Rajneesh , Lofty Khaled , Bala Indu 
Published: March 2024

AbstractThis paper introduces a novel model for a generalized thermoelastic medium with homogeneity and isotropy, by applying the Modified Green‐Lindsay (MG‐L) theory of thermoelasticity. The focus is on analysing the deformation due to time‐harmonic by considering the impact of non‐local and two‐temperature (TT) parameters. The governing equations are solved using dimensionless quantities and a potential function. To address the boundary value problem in the frequency domain, the Hankel transform is employed. Specific boundary conditions, such as a normal force or thermal source, are applied. Analytical expressions for components of displacement, stresses, conductive temperature, and temperature distribution are derived in the transformed domain A numerical inversion technique is utilised to translate the solution into the physical domain. The study delves into exploring the influence of non‐local and two‐temperature parameters, as well as different theories of thermoelasticity on stresses, temperature distribution and conductive temperature. These effects are visually represented through graphical illustrations. Additionally, special cases of interest are examined and discussed.
NLRC3 attenuates osteoclastogenesis by limiting TNFα+ Th17 cell response in osteoporosis
Authors: Ren Lingyan , Liu Guangjun , Bai Yun , Gu Liling , Wang Yuan , Sun Li 
Published: March 2024

Abstract
NOD-like receptor family CARD domain containing 3 (NLRC3) is the intracellular protein belonging to NLR (NOD-like receptor) family. NLRC3 can negatively regulate inflammatory signal transduction pathways within the adaptive and innate immunocytes. However, studies need to elucidate the biological role of NLRC3 in bone remodeling. Herein, our study proved that NLRC3 prevents bone loss by inhibiting TNFα+ Th17 cell responses. In osteoporosis, NLRC3 attenuated TNFα+ Th17 cell accumulation in the bone marrow. However, osteoporosis (OP) development was aggravated without affecting bone marrow macrophage (BMM) osteoclastogenesis in NLRC3-deficient ovariectomized (OVX) mice. In this study, we transferred the wild-type and NLRC3−/− CD4+ cells into Rag1−/− mice. Consequently, we evidenced the effects of NLRC3 in CD4+ T cells on inhibiting the accumulation of TNFα + Th17 cells, thus restricting bone loss in the OVX mice. Simultaneously, NLRC3−/− CD4+ T cells promoted the recruitment of osteoclast precursors and inflammatory monocytes into the OVX mouse bone marrow. Mechanism-wise, NLRC3 reduced the secretion of TNFα + Th17 cells of RANKL, MIP1α, and MCP1, depending on the T cells. In addition, NLRC3 negatively regulated the Th17 osteoclastogenesis promoting functions via limiting the NF-κB activation. Collectively, this study appreciated the effect of NLRC3 on modulating bone mass via adaptive immunity depending on CD4+ cells. According to findings of this study, NLRC3 may be the candidate anti-OP therapeutic target.

Key messages

NLRC3 negatively regulated the Th17 osteoclastogenesis promoting functions via limiting the NF-κB activation.

NLRC3 may be the candidate anti-OP therapeutic target.
Edible insect-processing techniques: a strategy to develop nutritional food products and novelty food analogs
Authors: Kozlu Ali , Ngasakul Nujamee , Klojdová Iveta , Baigts-Allende Diana Karina 
Published: March 2024

AbstractEdible insects have been part of the eating habits of several cultures over the years. They are recognized as a promising nutritional and sustainable alternative food source. The transformation of insects into safer and more acceptable food ingredients depends on the processing techniques and the final food system. Conventional methodologies such as blanching, boiling, drying, and milling are primarily used for material pre-conditioning and powder preparation, mostly for preparing bakery products. Most advanced technologies are preferred for extraction of insect derivatives such as lipids, proteins, polyphenols, and chitosan due to their better-quality preservation, higher yield, and more environmentally friendly (solvent residues). Insect derivatives (mainly lipids and proteins) have been used to enhance the nutritional value of processed products and to produce food analogs, principally for meat and less investigated for milk and dairy products. This literature overview summarizes the effect of different processing techniques on edible insects’ safety and quality and their use for the development of processed products and derivatives for food analogs production.
Promoting physical activity in rheumatoid arthritis through a physiotherapist led behaviour change-based intervention (PIPPRA): a feasibility randomised trial
Authors: Larkin Louise , McKenna Seán , Pyne Tadhg , Comerford Paul , Moses Anusha , Folan Ailish , Gallagher Stephen , Glynn Liam , Fraser Alexander , Esbensen Bente Appel , Kennedy Norelee 
Published: March 2024

AbstractPhysical activity (PA) is recommended as a key component in the management of people with rheumatoid arthritis (RA). The objective of this study was to examine the feasibility of a physiotherapist led, behaviour change (BC) theory-informed, intervention to promote PA in people with RA who have low levels of current PA. A feasibility randomised trial (ClinicalTrials.gov NCT03644160) of people with RA over 18 years recruited from outpatient rheumatology clinics and classified as insufficiently physically active using the Godin−Shephard Leisure Time Physical Activity Questionnaire. Participants were randomised to intervention group (4 BC physiotherapy sessions in 8 weeks) delivered in person/virtually or control group (PA information leaflet only). Feasibility targets (eligibility, recruitment, and refusal), protocol adherence and acceptability were measured. Health care professionals (HCPs) involved in the study and patients in the intervention and control arms were interviewed to determine acceptability. Descriptive statistics were used to analyse the data with SPSS (v27) with interviews analysed using content analysis using NVivo (v14). Three hundred and twenty participants were identified as potentially eligible, with n = 183 (57%) eligible to participate, of which n = 58 (32%) consented to participate. The recruitment rate was 6.4 per month. Due to the impact of COVID-19 on the study, recruitment took place over two separate phases in 2020 and 2021. Of the 25 participants completing the full study, 23 were female (mean age 60 years (SD 11.5)), with n = 11 allocated to intervention group and n = 14 to control. Intervention group participants completed 100% of sessions 1 & 2, 88% of session 3 and 81% of session 4. The study design and intervention were acceptable overall to participants, with enhancements suggested. The PIPPRA study to improve promote physical activity in people with RA who have low PA levels was feasible, acceptable and safe. Despite the impact of COVID-19 on the recruitment and retention of patients, the study provides preliminary evidence that this physiotherapist led BC intervention is feasible and a full definitive intervention should be undertaken. Health care professionals involved in the study delivery and the patient participants described a number of positive aspects to the study with some suggestions to enhance the design. These findings hence inform the design of a future efficacy-focused clinical trial.
Ureteroplasty with buccal mucosa graft without omental wrap: an effective method to treat ureteral strictures
Authors: Engelmann Simon U. , Yang Yushan , Pickl Christoph , Haas Maximilian , Goßler Christopher , Kälble Sebastian , Hartmann Valerie , Breyer Johannes , Burger Maximilian , Mayr Roman 
Published: March 2024

Abstract
Purpose
Successful treatment options for ureteral strictures are limited. Surgical options such as ileal interposition and kidney autotransplantation are difficult and associated with morbidity and complications. Techniques such as Boari flap and psoas hitch are limited to distal strictures. Only limited case studies on the success of open buccal mucosa graft (BMG) ureteroplasty exist to this date. The purpose of this study was to evaluate the success of open BMG ureteroplasty without omental wrap.

Methods
In this single-center retrospective study between July 2020 and January 2023, we included 14 consecutive patients with ureteric strictures who were treated with open BMG ureteroplasty without omental wrap. The primary outcome was the success of open BMG ureteroplasty. Further endpoints were complications and hospital readmission. Outcome variables were assessed by clinical examination, kidney sonography, and patient anamnesis.

Results
Out of 14 patients, 13 were stricture and ectasia-free without a double-J stent at a median follow-up of 15 months (success rate 93%). No complications were observed at the donor site, and the complication rate overall was low with 3 out of 14 patients (21%) having mild-to-medium complications.

Conclusions
Open BMG ureteroplasty without omental wrap is a successful and feasible technique for ureteric stricture repair.
Collective or individual rationality in the Nash bargaining solution: efficiency-free characterizations
Authors: Nakamura Kensei 
Published: March 2024

AbstractIn the classical bargaining problem, we propose a very mild axiom of individual rationality, which we call possibility of utility gain. This requires that for at least one bargaining problem, there exists at least one player who reaches a higher utility level than their disagreement utility. This paper shows that the Nash solution (Nash in Econometrica 18(2):155–162, 1950) is characterized by possibility of utility gain and continuity with respect to feasible sets together with Nash’s axioms except weak Pareto optimality. We also show that in Nash’s theorem, weak Pareto optimality can be replaced by conflict-freeness (introduced by Rachmilevitch in Math Soc Sci 76(C):107–109, 2015). This demands that when the agreement most preferred by all players is feasible, this should be chosen. Furthermore, we provide alternative and unified proofs for other efficiency-free characterizations of the Nash solution. This clarifies the role of each axiom in the related results.
Role of CD4+ T-cells for regulating splenic myelopoiesis and monocyte differentiation after experimental myocardial infarction
Authors: Gladow Nadine , Hollmann Claudia , Weirather Johannes , Ding Xin , Burkard Matthias , Uehlein Sabrina , Bharti Richa , Förstner Konrad , Kerkau Thomas , Beyersdorf Niklas , Frantz Stefan , Ramos Gustavo , Hofmann Ulrich 
Published: March 2024

AbstractMyocardial infarction (MI) induces the generation of proinflammatory Ly6Chigh monocytes in the spleen and the recruitment of these cells to the myocardium. CD4+ Foxp3+ CD25+ T-cells (Tregs) promote the healing process after myocardial infarction by engendering a pro-healing differentiation state in myocardial monocyte-derived macrophages. We aimed to study the effects of CD4+ T-cells on splenic myelopoiesis and monocyte differentiation. We instigated MI in mice and found that MI-induced splenic myelopoiesis is abrogated in CD4+ T-cell deficient animals. Conventional CD4+ T-cells promoted myelopoiesis in vitro by cell–cell-contact and paracrine mechanisms, including interferon-gamma (IFN-γ) signalling. Depletion of regulatory T-cells enhanced myelopoiesis in vivo, as evidenced by increases in progenitor cell numbers and proliferative activity in the spleen 5 days after MI. The frequency of CD4+ T-cells-producing factors that promote myelopoiesis increased within the spleen of Treg-depleted mice. Moreover, depletion of Tregs caused a proinflammatory bias in splenic Ly6Chigh monocytes, which showed predominantly upregulated expression of IFN-γ responsive genes after MI. Our results indicate that conventional CD4+ T-cells promote and Tregs attenuate splenic myelopoiesis and proinflammatory differentiation of monocytes.
First species record of Strigea falconis Szidat, 1928 (Trematoda, Strigeidae) from gyrfalcon Falco rusticolus in Iceland—pros and cons of a complex life cycle
Authors: Faltýnková Anna , Jouet Damien , Nielsen Ólafur Karl , Skírnisson Karl 
Published: March 2024

AbstractStrigea falconis is a common parasite of birds of prey and owls widely distributed in the Holarctic. We aimed to characterise S. falconis from Iceland via integrative taxonomic approach and to contribute to the understanding of its circulation in the Holarctic. We recovered adult S. falconis from two gyrfalcons (Falco rusticolus) collected in 2011 and 2012 in Iceland (Reykjanes Peninsula, Westfjords) and characterised them by morphological and molecular genetic (D2 of rDNA, cox1, ND1 of the mDNA) methods. We provide the first species record of S. falconis in Iceland which to the best of our knowledge is its northernmost distributional range. The presence of S. falconis in Iceland is surprising, as there are no suitable intermediate hosts allowing completion of its life cycle. Gyrfalcons are fully sedentary in Iceland; thus, the only plausible explanation is that they acquired their infection by preying upon migratory birds arriving from Europe. Our data indicate that the most likely candidates are Anseriformes and Charadriiformes. Also, we corroborate the wide geographical distribution of S. falconis, as we found a high degree of similarity between our haplotypes and sequences of mesocercariae from frogs in France and of a metacercaria from Turdus naumanni in Japan, and adults from Buteo buteo and Circus aeruginosus from the Czech Republic. The case of Strigea falconis shows the advantages of a complex life cycle and also depicts its pitfalls when a parasite is introduced to a new area with no suitable intermediate hosts. In Iceland, gyrfalcons are apparently dead-end hosts for S. falconis.