bluuebunny/crossref_metadata_2025_split huggingface dataset:
Prediction of Hospital Mortality Rates by Admission Laboratory Tests
Authors: Froom Paul , Shimoni Zvi 
Published: January 2006

Abstract
Background: The aim of this study was to explore whether electronically retrieved laboratory data can predict mortality in internal medicine departments in a regional hospital.
Methods: All 10 308 patients hospitalized in internal medicine departments over a 1-year period were included in the cohort. Nearly all patients had a complete blood count and basic clinical chemistries on admission. We used logistic regression analysis to predict the 573 deaths (5.6%), including all variables that added significantly to the model.
Results: Eight laboratory variables and age significantly and independently contributed to a logistic regression model (area under the ROC curve, 88.7%). The odds ratio for the final model per quartile of risk was 6.44 (95% confidence interval, 5.42–7.64), whereas for age alone, the odds ratio per quartile was 2.01 (95% confidence interval, 1.84–2.19).
Conclusions: A logistic regression model including only age and electronically retrieved laboratory data highly predicted mortality in internal medicine departments in a regional hospital, suggesting that age and routine admission laboratory tests might be used to ensure a fair comparison when using mortality monitoring for hospital quality control.
A Comparison of Intrazeolite and Solution Singlet Oxygen Ene Reactions of Allylic Alcohols
Authors: Clennan Edward L. , Zhang Dong , Singleton Jamie 
Published: January 2006

ABSTRACTThe singlet oxygen ene reactions of four allylic alcohols and for comparison an allylic ether have been examined both in solution and in zeolite Y. Brønsted acid sites in the zeolite were shown to induce decomposition of several of the allylic alcohols. Treatment of the zeolites with pyridine removed these acid sites and allowed intrazeolite reactions of the allylic alcohols without interference from decomposition. Control reactions with an allylic alcohol that is inert to decomposition provided evidence that the presence of pyridine in the zeolite labyrinth does not influence the product composition.
A Side Order of Stem Cells: The SP Phenotype
Authors: Challen Grant A. , Little Melissa H. 
Published: January 2006

Abstract
A defining property of murine hematopoietic stem cells (HSCs) is low fluorescence after staining with Hoechst 33342 and Rhodamine 123. These dyes have proven to be remarkably powerful tools in the purification and characterization of HSCs when used alone or in combination with antibodies directed against stem cell epitopes. Hoechst low cells are described as side population (SP) cells by virtue of their typical profiles in Hoechst red versus Hoechst blue bivariate fluorescent-activated cell sorting dot plots. Recently, excitement has been generated by the findings that putative stem cells from solid tissues may also possess this SP phenotype. SP cells have now been isolated from a wide variety of mammalian tissues based on this same dye efflux phenomenon, and in many cases this cell population has been shown to contain apparently multipotent stem cells. What is yet to be clearly addressed is whether cell fusion accounts for this perceived SP multipotency. Indeed, if low fluorescence after Hoechst staining is a phenotype shared by hematopoietic and organ-specific stem cells, do all resident tissue SP cells have bone marrow origins or might the SP phenotype be a property common to all stem cells? Subject to further analysis, the SP phenotype may prove invaluable for the initial isolation of resident tissue stem cells in the absence of definitive cell-surface markers and may have broad-ranging applications in stem cell biology, from the purification of novel stem cell populations to the development of autologous stem cell therapies.
Circumcaval ureter associated with an intrahepatic portosystemic shunt in a dog
Authors: Doust Ross T. , Clarke Stephen P. , Hammond Gawain , Paterson Calum , King Alison 
Published: January 2006

Abstract
Case Description—A 4-month-old Bernese Mountain Dog was examined because of shifting hind limb lameness and lethargy of 2 weeks' duration.
Clinical Findings—The lameness was attributed to hypertrophic osteodystrophy. Portosystemic shunting was suspected on the basis of low serum albumin concentration and high serum bile acids concentration, and an intrahepatic shunt was identified ultrasono-graphically. Celiotomy was performed, and the shunt was partially closed with a cellophane band. During follow-up ultrasonography 7 months later, dilation of the left renal pelvis and proximal portion of the left ureter was identified. During exploratory celiotomy, the left ureter was found to pass dorsal to the caudal vena cava, and circumcaval ureter was diagnosed.
Treatment and Outcome—The ureter was transected, repositioned ventral to the vena cava, and anastomosed. Follow-up ultrasonographic examinations revealed gradual resolution of the hydronephrosis and hydroureter.
Clinical Relevance—Findings suggest that circumcaval ureter should be considered in the differential diagnosis for hydronephrosis and hydroureter in dogs. Partial obstruction of the middle segment of the ureter on ultrasonograms or contrast radiographs should increase the index of suspicion for this condition.
Palliative use of a stent for colonic obstruction caused by adenocarcinoma in two cats
Authors: Hume Daniel Z. , Solomon Jeffrey A. , Weisse Chick W. 
Published: January 2006

Abstract
Case Description—Two adult male castrated cats were evaluated because of a history of constipation, tenesmus, or intermittent vomiting.
Clinical Findings—Radiography and ultrasonography revealed luminal narrowing in the colon of 1 cat and a colonic mass in the other. A histopathologic diagnosis of colonic adenocarcinoma was made in both cats.
Treatment and Outcome—Under fluoroscopic guidance, a self-expanding metallic stent was advanced over a wire and across the area of colonic stenosis and deployed. One cat had progressive weight loss but maintained a normal appetite, energy, and a high quality of life. Fecal continence was maintained, and tenesmus was rarely observed. The cat was euthanized because of tumor metastasis 274 days after the colonic stent was placed. The other cat retained fecal continence, and the owners reported subjective improvement in the severity of tenesmus, compared with that prior to stent placement. The cat was euthanized 19 days after stent placement because of perceived decreased quality of life.
Clinical Relevance—The use of self-expanding metallic stents for alleviation of colonic obstruction secondary to adenocarcinoma in cats appears to be effective. This technique provides a simple, quick, nonsurgical option for palliation in cats with advanced metastatic or systemic disease in which surgical resection may not be possible or warranted.
Extensive small bowel resection in dogs and cats: 20 cases (1998–2004)
Authors: Gorman Stephanie C. , Freeman Lisa M. , Mitchell Susan L. , Chan Daniel L. 
Published: January 2006

Abstract
Objective—To determine outcome in dogs and cats that underwent extensive (ie, > 50%) resection of the small intestine and identify factors associated with outcome.
Design—Retrospective case series.
Animals—13 dogs and 7 cats.
Procedure—Medical records were reviewed, and follow-up information was obtained.
Results—In all 7 cats and in 8 of the 13 dogs, extensive intestinal resection was performed because of a foreign body. Mean ± SD estimated percentage of intestine that was removed was 68 ± 14% (range, 50% to 90%). Two dogs were euthanized 3 days after surgery because of dehiscence of the surgical site and development of septic peritonitis; 1 dog died of acute respiratory distress syndrome 5 days after surgery. The remaining 10 dogs and 7 cats were discharged from the hospital, and follow-up information was available for 15 of the 17. Median survival time was 828 days, and 12 of the 15 animals for which long-term follow-up information was available had good outcomes. However, none of the factors examined, including percentage of intestine resected, were significantly associated with outcome.
Conclusions and Clinical Relevance—Most dogs and cats that underwent extensive resection of the small intestine had a good outcome. The amount of intestine resected was not associated with outcome. These data may be useful in providing prognostic information in cases of extensive small intestinal resection.
Efficacy of vaccination and antimicrobial treatment to eliminate chronic intramammary Staphylococcus aureus infections in dairy cattle
Authors: Smith Geof W. , Lyman Roberta L. , Anderson Kevin L. 
Published: January 2006

Abstract
Objective—To determine whether a combination of vaccination and extended intramammary antimicrobial treatment would eliminate chronic intramammary Staphylococcus aureus infections in lactating dairy cows.
Design—Randomized controlled clinical trial.
Animals—50 dairy cows with chronic mastitis caused by S aureus.
Procedure—Cows were identified and paired within herd on the basis of days in milk, lactation number, milk production, and numbers of quarters infected. Treated cows (n = 20) received 3 doses of a polyvalent S aureus bacterin on days 1, 15, and 21 of the study along with intramammary administration of pirlimycin in all 4 quarters once daily for 5 treatments (days 16 to 20). Control cows (n = 23) received no treatment. Follow-up samples for bacteriologic culture were collected for at least 3 months after treatment to determine treatment success rates.
Results—Significantly more S aureus infections were eliminated from treated cows (8/20 [40%]), compared with control cows (2/23 [9%]). The proportion of infected quarters that yielded negative results throughout the follow-up period was also significantly higher in treated cows (13/28 [46%]) than in control cows (2/41 [5%]).
Conclusions and Clinical Relevance—Results indicate that a combination of vaccination and antimicrobial treatment can be successful in eliminating some cases of chronic intramammary S aureus infections in dairy cattle. However, it is important to consider extended treatment protocols carefully because many cows are likely to remain infected with S aureus despite treatment and vaccination.
The bacterial pathogen Pseudomonas plecoglossicida, its epidemiology, virulence factors, vaccine development, and host–pathogen interactions
Authors: Mao Zhijuan , Li Shanshan , Li Yiying , Jia Tingting 
Published: February 2024

Abstract

Objective
Pseudomoans plecoglossicida has been identified as a fish pathogen since 2000 and has caused serious infections in cultured Large Yellow Croakers Larimiththys crocea in coastal eastern China during recent years.

Methods
Published literatures of this pathogen have been reviewed.

Result
Several strains with high genomic similarity have been isolated and identified; the bacteria induce natural infection at lower water temperatures (12.0–25.5°C) and induce numerous granulomas and nodules in the visceral organs of croakers. Researchers have investigated the epidemiology of P. plecoglossicida infection, identified major virulence factors, searched for pathogenic genes, analyzed host-pathogen interactions, and endeavored to develop efficient vaccines.

Conclusion
This paper provides an overview of these research advances to elucidate the virulence mechanisms of the pathogen and to promote vaccine development against infection.
A Thermosensitive Hydrogel with Efficient NIR Photothermal Conversion as Injectable Wound Dressing for Accelerating Skin Wound Healing
Authors: Wu Jing , Wang Wentao , Shen Jian , Zhou Ninglin , Li Yuanyuan , Tang Ben Zhong , Zhang Ming 
Published: February 2024

AbstractBacterial infection at wound sites can easily induce robust inflammation. M1 macrophages at wound sites can cause cascade inflammatory reactions to mediate a vicious inflammation cycle. Meanwhile, the hypoxia situation further aggravates the destruction and contraction of blood vessels in the wound microenvironment, therefore, hindering the infected wound healing process. Here, a thermosensitive hydrogel is reported to solve the above challenges by eliminating bacteria based on the photothermal effect, regulating the inflammatory immune microenvironment, and providing oxygen (O2). In vitro and in vivo experiments confirmed that the hydrogel has great O2‐producing properties. Based on the excellent photothermal properties of AIEgens, the hydrogel has a good bactericidal effect against S. aureus (100%) and E. coli (98.85%). The RNA‐sequencing revealed that Cur@AIE@MnO2/gel can interfere with the metabolic process and genetic material repair process to impact bacteria proliferation and biofilm dispersal, thus achieving excellent anti‐bacterial efficacy. Moreover, Cur@AIE@MnO2/gel can also up‐regulate anti‐inflammatory genes, down‐regulate pro‐inflammatory genes in macrophages, and facilitate the promotion of macrophage polarization from M1 to M2 to relieve inflammation. The therapeutic experiments show that this hydrogel accelerated the wound‐healing process. Therefore, this work may open new avenues for the development of novel dressings for bacterial‐infected wounds.
Bioinspired Integrated Multidimensional Sensor for Adaptive Grasping by Robotic Hands and Physical Movement Guidance
Authors: Lei Peng , Bao Yan , Gao Lu , Zhang Wenbo , Zhu Xiaofeng , Liu Chao , Ma Jianzhong 
Published: February 2024

AbstractThe construction of piezoresistive sensors capable of distinguishing multiple mechanical stimuli is important for sensing higher level applications. However, the mutual interference between sensing signals is a technical bottleneck for sensors to recognize multiple mechanical stimuli. Inspired by the structure of human skin and muscle, a multidimensional sensor is designed by integrating three sub‐sensors. Each sub‐sensor is only sensitive to stimulus components in one of the three orthogonal axes, whereas it remains insensitive to others because of its anisotropic sensing properties. Specifically, an omnidirectional gradient wrinkled polyurethane film with MXene‐embedded ZnO nanowire arrays serves as a strain‐insensitive pressure sub‐sensor, while two aligned segmental polyimide/polyurethane films through orthogonal stacking act as two pressure‐insensitive anisotropic strain sub‐sensors. A unique characteristic of multidimensional sensor is its ability to distinguish and measure the type, magnitude, and direction of strain, pressure, and shear. Moreover, multidimensional sensor exhibits maximal gauge factor of 863.7 for strain and highest sensitivity of 187.71 kPa−1 for pressure. Importantly, multidimensional sensor exhibits an unprecedented ability to quantitatively evaluate shear using a library of electrical responses. The adaptive grasping of robotic hands and free‐throw training of players have been demonstrated to initiate the development of robotic object manipulation and physical movement guidance.
Spider Silk/Hemin Biobased Electrets for Organic Phototransistor Memory: A Comprehensive Study on Solution Process Engineering
Authors: Hsu Chih‐Wei , Yu Sheng‐Kai , Shen Ming‐Yan , Ercan Ender , Wang Yi‐Jen , Lin Bi‐Hsuan , Wu Hsuan‐Chen , Lin Yan‐Cheng , Liu Cheng‐Liang , Chen Wen‐Chang 
Published: February 2024

AbstractThe escalating environmental impact of pollution and the imperative to reduce carbon emissions have heightened the significance of developing biobased materials from natural biomass for electronic devices. This study investigates the utilization of biofermentation‐produced recombinant spider silk and animal‐derived hemin to create a novel biobased electret for field‐effect transistor memory. A critical challenge arises from the incompatibility between natural photoresponsive molecules and insulating biomaterials, resulting in severe phase separation that compromises film quality and morphology uniformity. This study systematically examines the effects of various film deposition and manufacturing techniques on the biobased electret's morphology, phase separation, and performance. Different methods demonstrate distinct advantages in terms of molecular aggregation/segregation, morphological homogeneity, and device performance. Phototransistor memory devices fabricated using spin coating and spray coating techniques exhibit robust aggregations and high memory windows of ≈30 V. Conversely, devices produced through solution shearing and electrospinning methods display enhanced smooth morphologies and high photoresponsivity. The phototransistor memory comprising electrospun fibers holds the potential to achieve the highest memory ratio, reaching ≈105. These findings not only highlight the applications of biobased materials through scalable film deposition processes but also underscore the importance of refining their morphology, phase separation, and performance in optoelectronic devices.
Anion/Cation Solvation Engineering for a Ternary Low‐Concentration Electrolyte toward High‐Voltage and Long‐Life Sodium‐Ion Batteries
Authors: Wang Xinyu , Yang Cheng , Yao Lingbo , Wang Yichao , Jiang Ning , Liu Yu 
Published: February 2024

AbstractHigh‐voltage sodium‐ion batteries (SIBs) are one of the most promising energy storage technologies for abundant resources and cost‐efficiency. However, their low energy density compared with lithium‐ion batteries (LIBs) hinders their practical applications. The high reactivity of high‐voltage cathodes, the primary factor, leads to deterioration of electrode/electrolyte interphase. Herein, a novel anion/cation solvation strategy is innovatively proposed for a ternary low‐concentration electrolyte that tackles the critical bottleneck of unstable electrode/electrolyte interphase. Especially, the intermolecular interaction within as‐designed electrolyte is remodeled by weakly polar fluorinated co‐solvent (ethoxy(pentafluoro)cyclotriphosphazene, PFPN) compared with traditional carbonate‐based electrolytes. PFPN can not only stabilize propylene carbonate (PC), reduce the interaction of Na+‐PC, ClO4−, accelerating Na+ desolvation, but also weaken the interaction of anions to form stable organic/inorganic composite cathode electrolyte interphase (CEI). In this work, the ionic conductivity of low‐concentration electrolyte increases to 6.12 mS cm−1 and the oxidation stability is successfully extended to 4.84 V. And Na3V2(PO4)2F3 (NVPF)||Na half‐cells present excellent cycling performance with average coulombic efficiency of 99.5% after 2000 cycles at 4.5 V and NVPF||hard carbon (HC) full cells with relatively high energy density (≈450 Wh kg−1) competitive to commercial LIBs, which are expected to be coupled with higher voltage cathodes to achieve higher energy density in future.
A High‐Power Rechargeable Sodium‐Ion Full Battery Operating at −40 °C
Authors: Wang Yingyu , Lan Hao , Dong Shuai , Zhu Qiaonan , Cheng Liwei , Wang Han , Wang Jiawei , Wang Sicong , Tang Mengyao , Shodievich Kurbаnov Mirtemir , Wang Gongkai , Wang Hua 
Published: February 2024

AbstractHigh‐power‐density rechargeable batteries are highly indispensable for power‐intensive application scenarios, such as vehicle start‐stop system and grid‐level frequency regulation. However, realizing high‐power‐density alkali‐ion batteries is challenging especially at low temperatures, as undesirable alkali metal plating tends to occur more easily on the anode surface due to the increased electrochemical impedance and polarization. Herein, a low‐temperature, high‐power‐density rechargeable Na3V2(PO4)3 ||hard carbon (HC) sodium‐ion full battery without Na plating is realized by electrolyte regulation. The designed high‐solvation‐entropy electrolyte enables a high ionic conductivity of 13.87 mS cm−1 at −40 °C. More importantly, the enhanced contact‐ion pairs solvation structure induces an anion‐derived, thin, NaF‐rich solid electrolyte interface (SEI) on HC anodes with low interfacial resistance to ensure facile Na+ diffusion through the SEI. Consequently, the assembled sodium‐ion full battery demonstrates a record‐high power density of 1132.31 W kg−1 (with an energy density of 61.94 Wh kg−1) at −40 °C and 13372.56 W kg−1 (132.83 Wh kg−1) at 25 °C (based on total mass of the active materials on anode and cathode). This work will expedite the development of sodium‐ion batteries for power‐intensive applications in extreme environments.
High‐Capacity, Long‐Life Sulfide All‐Solid‐State Batteries with Single‐Crystal Ni‐Rich Layered Oxide Cathodes
Authors: Liu Huan , Wang Yue , Chen Liquan , Li Hong , Wu Fan 
Published: February 2024

AbstractSulfide all‐solid‐state battery (SASSB) with ultrahigh‐nickel layered oxide cathode (LiNixCoyMn1‐x‐yO2, NCM, x ≥ 0.9) offers the potential of high energy density and safety for superior energy storage systems. However, stable cycling is difficult to realize due to adverse interfacial reactions, space charge layer (SCL), and elemental diffusion. Herein, a straightforward solid‐phase coating strategy is exploited to synthesize Ni90‐S cathode, which greatly improves the charge transmission capability of the composite cathode and suppresses interfacial reactions in SASSB. The consequent SC‐Ni90‐0.2%S/Li6PS5Cl/Li4Ti5O12 SASSB exhibits enhanced electrochemical performance, including a long life of 500 cycles with 87% capacity retention at 1C, high areal capacity of 11.44 mAh cm−2, and excellent rate performance at 20 C. These results promise an efficient strategy for designing cathode materials for SASSBs.
Efforts Toward the Fabrication of Thermoelectric Cooling Module Based on N‐Type and P‐Type PbTe Ingots
Authors: Liu Shibo , Qin Yongxin , Wen Yi , Shi Haonan , Qin Bingchao , Hong Tao , Gao Xiang , Cao Qian , Chang Cheng , Zhao Li‐Dong 
Published: February 2024

AbstractThermoelectric cooling has gained much attention due to its significant application in 5G communication chip cooling. Enhancing the performance of thermoelectric cooling devices is an imminent and pressing concern. Applying the same material for both n‐type and p‐type components can promote the compatibility of thermoelectric cooling module due to their similar mechanical properties. This work focuses on the development of thermoelectric cooling module based on n‐type and p‐type PbTe ingots. The high ZT values near room temperature are achieved through fabricating PbTe ingots. This approach substantially enhances the carrier mobility by minimizing charge carrier scattering at grain boundaries compared to polycrystals. These optimized ingots are then utilized to construct a thermoelectric cooling device consisting of seven pairs of thermoelectric couples, which achieves a maximum cooling temperature difference of ≈14 K at room temperature and ≈28 K at 350 K. This study offers fresh insights into the development of thermoelectric cooling module using PbTe‐based materials.