bluuebunny/crossref_metadata_2025_split huggingface dataset:
Thermal performance analysis of hollow bricks integrated phase change materials for various climate zones
Authors: Babaharra Oumayma , Choukairy Khadija , Faraji Hamza , Khallaki Kaoutar , Hamdaoui Said , Bahammou Younes 
Published: February 2024

AbstractThis comprehensive research addresses the significant challenge of building‐related energy consumption in Morocco. Our innovative approach involves integrating phase change materials (PCMs) into hollow bricks, strategically addressing the diverse climate zones prevalent in the country. The primary focus is on enhancing energy efficiency within structures. Leveraging detailed simulations and employing the enthalpy‐porosity approach, our study models the impact of PCMs on internal temperatures. Optimal outcomes are achieved by partially filling brick holes with PCMs in specific configurations, demonstrating the materials' ability to adapt to varying conditions. A noteworthy finding is the 2–3‐h phase shift observed in cold zones, indicating the potential for PCMs to effectively regulate temperatures. Equally significant is their capability to maintain a constant internal temperature of 26°C in hot zones, even amidst extreme external conditions reaching up to 47°C. This resilience underscores the novel and tailored thermal regulation potential of PCMs. Beyond the technical insights, our research highlights the paramount importance of considering regional climates in PCM applications' implementation. This awareness is crucial for optimizing energy performance in buildings and ensuring sustainability. In essence, this study contributes valuable knowledge and practical implications for the strategic deployment of PCMs to enhance building energy efficiency, emphasizing the need for context‐specific solutions in diverse environmental conditions.
Preoperative diagnosis of ureteral medial deviations secondary to deep endometriosis using transvaginal ultrasound examinations: Can we predict the need for ureterolysis during laparoscopic surgery?
Authors: Carfagna Pietro , De Cicco Nardone Alessandra , Benvenga Greta , Nardone Fiorenzo De Cicco , Greco Pierfrancesco , Campolo Federica , Pafundi Pia Clara , Alesi Maria Vittoria , Testa Antonia Carla , Scambia Giovanni , Ianieri Manuel Maria 
Published: February 2024

AbstractObjectiveTo evaluate ureteral involvement using transvaginal sonography (TVS) regarding the distortion of the course of the ureters caused by deep endometriosis (DE), which can facilitate predicting the need for ureterolysis during surgery, even in the absence of ureteral stenosis or dilatation.MethodsThis is a single‐center, observational, retrospective pilot study of 88 consecutive patients who later underwent surgery for DE that used ultrasound preoperative diagnosis of ureteral medial deviation of one or both ureters between January 2019 and January 2022. At TVS, the course of the ureter was considered medialized if, in longitudinal and transversal section, any distance was detectable between the ureter and the cervix at the point where the ureter crosses the uterine artery. The primary end point was to determine sensitivity, specificity, and positive and negative predictive values of “ureteral medial deviation” diagnosed using TVS, in order to predict the need for ureterolysis.ResultsOur series included 88 women with a median age of 39 (interquartile range 33–43) years. Ureteral medialization showed a relatively low false‐positive rate (10.9%), with a specificity of 89.1% (95% confidence interval [CI] 81.4%–96.7%) and a sensitivity of 86.6% (95% CI 80.3%–92.9%), along with a high positive predictive value of 93.3% (95% CI 88.4%–98.1%), and a lower negative predictive value of 79.1% (95% CI 69.8%–88.5%), respectively.ConclusionsThis study introduced a new ultrasound sign with a high degree of accuracy to predict ureterolysis and this may have positive implications in the management and surgical planning of patients with ureteral endometriosis.
Oxytocin and vaginal dinoprostone in labor induction: A systematic review and meta‐analysis
Authors: Chang Ting‐An , Li Yi‐Rong , Ding Dah‐Ching 
Published: February 2024

AbstractBackgroundThe comparison between prostaglandin E2 (PGE2) and oxytocin and for induction of labor (IOL) remains controversial.ObjectiveThe present study aimed to determine the safety and efficacy of these two agents in IOL.Search StrategyPubMed, Embase, Web of Science, Cochrane Library, andClinicalTrials.gov. from the establishment of the database to April 23, 2023.Selection CriteriaA search was conducted with keywords “labor, induction, prostaglandin E2/PGE2/dinoprostone, and oxytocin”. Only randomized clinical trials comparing oxytocin and vaginal dinoprostone in women who were at least late preterm (gestational age [GA] ≥34 weeks), singleton pregnant, and had intact membranes were enrolled for further meta‐analysis.Data Collection and AnalysisWe conducted both a descriptive analysis and a meta‐analysis. In the meta‐analysis, we utilized the Mantel–Haenszel random effects model to analyze dichotomous data, employing the relative risk (RR) as the effect measure along with 95% confidence intervals (CIs). The study quality was evaluated using Cochrane Collaboration's risk of bias assessment tool (RoB 2). A random‐effects model was applied for the meta‐analysis.Main ResultsAfter screening 3303 articles from five databases, a total of nine randomized controlled studies composed of 1071 patients were included. Our analysis included 534 patients in the PGE2 group and 537 patients in the oxytocin group. The pooled estimate of vaginal deliveries following PGE2 induction stood at 84.2%, while after oxytocin induction, it was 79.8%. The meta‐analysis showed no statistical difference between the two groups in terms of the rate of vaginal delivery (pooled RR, 1.05; 95% CI: 0.95–1.16;Pvalue forQ, 0.001;I2, 71.14%), cesarean section (pooled RR, 0.84; 95% CI: 0.52–1.35;Pvalue forQ, 0.007;I2, 61.69%) and induction‐delivery interval (pooled standard mean difference, 0.09; 95% CI: −0.67 to 0.85;Pvalue forQ, 0.000;I2, 96.45%). Since the results for fetal distress and uterine hyperstimulation were consistent across all enrolled studies, no further meta‐analysis was conducted.ConclusionsWhen amalgamating the available literature, it implies that oxytocin was found to have similar effects as PGE2 on delivery outcomes and safety concerns in pregnant women with GA ≥36 weeks. Although the uterine cervix was unfavorable, both low and high doses of oxytocin were feasible for IOL.
A pilot study of the behavioral addictions knowledge survey: Ensuring students’ knowledge about process/behavioral addictions
Authors: Ricciutti Natalie M. , Zhang Sijia 
Published: February 2024

AbstractFuture counselors are likely to work with clients with process/behavioral addictions (PBA). The behavioral addiction knowledge survey (BAKS) was designed to determine counseling students’ knowledge of PBAs. This article presents the instrument development procedures and results of a preliminary exploratory factor analysis (EFA) and a Rasch analysis of the BAKS. The sample size included 77 counseling students. The EFA suggested a three‐factor, 18‐item solution, with satisfactory internal consistency within each factor. Rasch analysis results also yielded excellent infit and outfit statistics. Detailed psychometric properties of the BAKS are provided. Implications for counselor educators, supervisors, and future researchers are included.
Machine learning assisted analysis of equivalent circuit usage in electrochemical impedance spectroscopy applications
Authors: Klemm Carl Philipp , Frömling Till 
Published: February 2024

AbstractElectrical equivalent circuits are a widely applied tool with which electrical processes can be rationalized. There is a wide‐ranging selection of fields from bioelectrochemistry to batteries to fuel cells making use of this tool. Enabling meta‐analysis on the similarities and differences in the used circuits will help to identify commonly used circuits and aid in evaluating the underlying physics. We present a method and an implementation that enables the conversion of circuits included in scientific publications into a machine‐readable form for generating machine learning datasets or circuit simulations.
AMP‐activated protein kinase as a mediator of mitochondrial dysfunction of multiple sclerosis in animal models: A systematic review
Authors: Askari Hamid , Rabiei Fatemeh , Lohrasbi Fatemeh , Ghadir Sara , Mehdipour Arbastan Ahmad , Ghasemi‐Kasman Maryam 
Published: February 2024

AbstractMultiple sclerosis (MS) is a chronic central nervous system (CNS) disorder characterized by demyelination, neuronal damage, and oligodendrocyte depletion. Reliable biomarkers are essential for early diagnosis and disease management. Emerging research highlights the role of mitochondrial dysfunction and oxidative stress in CNS disorders, including MS, in which mitochondria are central to the degenerative process. Adenosine monophosphate‐activated protein kinase (AMPK) regulates the mitochondrial energy balance and initiates responses in neurodegenerative conditions. This systematic review, following Preferred Reporting Items for Systematic Reviews and Meta‐Analyses guidelines, aimed to comprehensively assess the literature on AMPK pathways, mitochondrial dysfunction, and in vivo studies using MS animal models. The search strategy involved the use of AMPK syntaxes, MS syntaxes, and animal model syntaxes. The PubMed, Scopus, Web of Science, and Google Scholar databases were systematically searched on August 26, 2023 without publication year restrictions. The review identified and analyzed relevant papers to provide a comprehensive overview of the current state of related research. Eight studies utilizing various interventions and methodological approaches were included. Risk of bias assessment revealed some areas of low risk but lacked explicit reporting in others. These studies collectively revealed a complex relationship between AMPK, mitochondrial dysfunction, and MS pathogenesis, with both cuprizone and experimental autoimmune encephalomyelitis models demonstrating associations between AMPK and mitochondrial disorders, including oxidative stress and impaired expression of mitochondrial genes. These studies illuminate the multifaceted role of AMPK in MS animal models, involving energy metabolism, inflammatory processes, oxidative stress, and gene regulation leading to mitochondrial dysfunction. However, unanswered questions about its mechanisms and clinical applications underscore the need for further research to fully harness its potential in addressing MS‐related mitochondrial dysfunction.
A comparative study on the antennae morphology and ultrastructure of three mud crab species of the genus Scylla from Setiu Wetlands, Terengganu, Malaysia
Authors: Achdiat Muhammad , Tan Kian Ann , Fujaya Yushinta , Wang Youji , Martin Melissa Beata , Shu‐Chien Alexander Chong , Fazhan Hanafiah , Waiho Khor 
Published: February 2024

AbstractCrustaceans possess a range of sensory organs crucial in sensory perception, communication, and various ecological functions. Understanding morphological and functional differences in antennae among species could validate taxonomic differentiation and ecological adaptations. The antennae morphology and ultrastructure of mud crab species within the Scylla genus are poorly understood, and their role in ecological adaptation and species differentiation remains unexplored. This study aimed to describe and compare the morphology and ultrastructure of antennae in Scylla olivacea, Scylla tranquebarica, and Scylla paramamosain. Antennae were carefully excised from each crab and subjected to morphological, morphometric, and ultrastructural analysis. The study revealed that the antennae of Scylla species exhibit similar overall morphology, with a series of segments that tapered toward the upper end. All species possess non‐branched single setae on the upper end of each segment. The number of antennae segments varied between species, with S. paramamosain having significantly more segments than S. olivacea. Additionally, the length and width of antenna segments differed among the species, with S. tranquebarica having a rougher antenna surface compared to S. olivacea and S. paramamosain. Our findings suggest that Scylla's antennae are distinct between species, especially in the number of segments and setae size. Such difference might be related to ecological adaptation. The role of antennae in sensory perception and social behavioral cues in mud crabs warrants further investigation. This study serves as a foundational reference for future research on the taxonomy, ecological adaptation, and sensory behaviors in the Scylla genus.Research Highlights
Variations and similarities in morphology and ultrastructure of three Scylla species can be found in the antennae.
Scylla paramamosain had significantly higher number of segments than Scylla olivacea in morphology feature.
The antennae surface of Scylla tranquebarica was rougher than that of S. olivacea and S. paramamosain.
Antennae of three Scylla species possess non‐branched single setae.
Variants of a major DNA satellite discriminate parental subgenomes in a hybrid parthenogenetic lizard Darevskia unisexualis (Darevsky, 1966)
Authors: Nikitin Pavel , Sidorov Sviatoslav , Liehr Thomas , Klimina Ksenia , Al‐Rikabi Ahmed , Korchagin Vitaly , Kolomiets Oxana , Arakelyan Marine , Spangenberg Victor 
Published: February 2024

AbstractHybrid parthenogenetic animals are an exceptionally interesting model for studying the mechanisms and evolution of sexual and asexual reproduction. A diploid parthenogenetic lizard Darevskia unisexualis is a result of an ancestral cross between a maternal species Darevskia raddei nairensis and a paternal species Darevskia valentini and presents a unique opportunity for a cytogenetic and computational analysis of a hybrid karyotype. Our previous results demonstrated a significant divergence between the pericentromeric DNA sequences of the parental Darevskia species; however, an in‐depth comparative study of their pericentromeres is still lacking. Here, using target sequencing of microdissected pericentromeric regions, we reveal and compare the repertoires of the pericentromeric tandem repeats of the parental Darevskia lizards. We found species‐specific sequences of the major pericentromeric tandem repeat CLsat, which allowed computational prediction and experimental validation of fluorescent DNA probes discriminating parental chromosomes within the hybrid karyotype of D. unisexualis. Moreover, we have implemented a generalizable computational method, based on the optimization of the Levenshtein distance between tandem repeat monomers, for finding species‐specific fluorescent probes for pericentromere staining. In total, we anticipate that our comparative analysis of Darevskia pericentromeric repeats, the species‐specific fluorescent probes that we found and the pipeline that we developed will form a basis for the future detailed cytogenomic studies of a wide range of natural and laboratory hybrids.
Comparing application methods of reishi mushroom (Ganoderma lucidum) extract in deep‐fried meatballs: impact on heterocyclic aromatic amine formation
Authors: Guzel Bengu , Gumus Damla , Kizil Mevlude 
Published: February 2024

AbstractBACKGROUNDThe present research was conducted to investigate the impact of reishi mushroom extract (RME) on the formation of heterocyclic aromatic amines (HAAs) in meatballs. Sample preparations involved applying RME using either the spreading or addition method, with varying concentrations (0%, 0.25%, 0.5%, and 1% of RME), followed by deep‐frying at temperatures of 150 and 190 °C for 3 min.RESULTSThe types and levels of HAAs varied based on the frying temperature, method of extract application, and the extract concentration. Notably, total HAA contents increased with rising the frying temperature (P < 0.01) and varied from undetectable levels to 4.91 ng g−1 across all analyzed meatballs. The addition method was more effective than the spreading method (P < 0.01), and among the concentrations tested 0.25% RME exhibited the highest efficacy in reducing total HAAs (P < 0.05). Furthermore, the addition method inhibited lipid oxidation more efficiently compared to the surface spreading method (P < 0.05).CONCLUSIONThis study demonstrated that RME had mitigating effects on HAAs depending on the concentration and frying conditions in deep‐fried meatball samples. © 2024 The Author(s). Journal of The Science of Food and Agriculture published by John Wiley & Sons Ltd on behalf of Society of Chemical Industry.
Race and Ethnicity Independently Predict Adverse Outcomes Following Head and Neck Autograft Surgery
Authors: Ferraro Tatiana , Ahmed Abdulla K. , Lee Esther , Lee Sean M. , Debbaneh Peter M. , Thakkar Punam , Joshi Arjun , Tummala Neelima 
Published: February 2024

ObjectiveThere is growing attention toward the implications of race and ethnicity on health disparities within otolaryngology. While race is an established predictor of adverse head and neck oncologic outcomes, there is paucity in the literature on studies employing national, multi‐institutional data to assess the impact of race and ethnicity on head and neck autograft surgery.MethodsUsing the National Surgical Quality Improvement Program (NSQIP) database, trends in 30 days outcomes were assessed. Patients with ICD‐10 codes for malignant head and neck neoplasms were isolated. Autograft surgeries were selected using Current Procedural Terminology (CPT) codes for free flap and pedicled flap reconstruction. Primary outcomes included surgical complications, reoperation, readmission, extended length of stay and operation time. Each binary categorical variable was compared to racial/ethnic identity via binary logistic regression.ResultsThe study cohort consisted of 2447 patients who underwent head and neck autograft surgery (80.71% free flap reconstruction and 19.39% pedicled flap reconstruction). Black patients had significantly higher odds of overall surgical complications (odds ratio [OR] 1.583, 95% confidence interval [CI] 1.091, 2.298, p = 0.016) with much higher odds of perioperative blood transfusions (OR 2.291, 95% CI 1.532, 3.426, p = <.001). Hispanic patients were more likely to undergo reoperation within 30 days after surgery and were more likely to be hospitalized for more than 30 days post‐operatively (OR 1.566, 95% CI 1.015, 2.418, p = 0.043 and OR 12.224, 95% CI 2.698, 55.377, p = 0.001, respectively).ConclusionsRace and ethnicity serve as independent predictors of complications in the post‐operative period following head and neck autograft surgery.Level of Evidence3 Laryngoscope, 134:3595–3603, 2024
Temperature stress (cold and heat) strongly affect the phytotoxicity of polycyclic aromatic hydrocarbon (phenanthrene) to wheat
Authors: Suszek‐Łopatka Beata , Maliszewska‐Kordybach Barbara , Klimkowicz‐Pawlas Agnieszka , Smreczak Bożena 
Published: February 2024

AbstractAnthropogenic activity could create different threats leading to irreversible changes in the global environment and, as a consequence, posing varied stressful conditions acting together (combined stress) on organisms. Our research concerned the combined stress of two of the main threats to soil health and plant health: temperature stress and pollution. The aim of this research was the quantitative assessment of the impact of temperature stress on the phytotoxicity of PAHs (polycyclic aromatic hydrocarbons; specifically, phenanthrene, which is a widespread, harmful organic contamination of soil) on the growth of wheat seedlings in relation to the level of soil contamination by phenanthrene (0–1000 mg kg−1 dry mass of soil) and the type of temperature stress: cold (10°C) and heat (35°C) stress, in three different soils. Earlier studies have investigated the effect of temperature stress on PAH toxicity mainly on soil invertebrates. However, the impact of temperature stress on PAH phytotoxicity towards crop plants, which are important for human food security but could be affected by chemical soil degradation, is still poorly understood. Our results indicated that the phenanthrene phytotoxicity was significantly enhanced by cold stress and heat stress. The effects of cold and heat temperature stress increased with increasing phenanthrene level. Our research is important for improving the risk assessment of PAH and food security forecasting.
Lotic‐SIPCO2: Adaptation of an open‐source CO2 sensor system and examination of associated emission uncertainties across a range of stream sizes and land uses
Authors: Robison Andrew L. , Koenig Lauren E. , Potter Jody D. , Snyder Lisle E. , Hunt Christopher W. , McDowell William H. , Wollheim Wilfred M. 
Published: February 2024

AbstractRiver networks play a crucial role in the global carbon cycle, as relevant sources of carbon dioxide (CO2) to the atmosphere. Advancements in high‐frequency monitoring in aquatic environments have enabled measurement of dissolved CO2 concentration at temporal resolutions essential for studying carbon variability and evasion from these dynamic ecosystems. Here, we describe the adaptation, deployment, and validation of an open‐source and relatively low‐cost in situ pCO2 sensor system for lotic ecosystems, the lotic‐SIPCO2. We tested the lotic‐SIPCO2 in 10 streams that spanned a range of land cover and basin size. Key system adaptations for lotic environments included prevention of biofouling, configuration for variable stage height, and reduction of headspace equilibration time. We then examined which input parameters contribute the most to uncertainty in estimating CO2 emission rates and found scaling factors related to the gas exchange velocity were the most influential when CO2 concentration was significantly above saturation. Near saturation, sensor measurement of pCO2 contributed most to uncertainty in estimating CO2 emissions. We also found high‐frequency measurements of pCO2 were not necessary to accurately estimate median emission rates given the CO2 regimes of our streams, but daily to weekly sampling was sufficient. High‐frequency measurements of pCO2 remain valuable for exploring in‐stream metabolic variability, source partitioning, and storm event dynamics. Our adaptations to the SIPCO2 offer a relatively affordable and robust means of monitoring dissolved CO2 in lotic ecosystems. Our findings demonstrate priorities and related considerations in the design of monitoring projects of dissolved CO2 and CO2 evasion dynamics more broadly.
A novel gain‐of‐function STAT3 variant in infantile‐onset diabetes associated with multiorgan autoimmunity
Authors: Zhou Qiaoli , Chen Dandan , Yu Jing , Zheng Bixia , Zhou Wei , Jia Zhanjun , Zhang Aihua , Gu Wei 
Published: February 2024

AbstractBackgroundGermline gain‐of‐function (GOF) variants in the signal transducer and activator of transcription 3 (STAT3) gene lead to a rare inherited disorder characterized by early‐onset multiorgan autoimmunity.MethodsWe described a Chinese patient with infantile‐onset diabetes and multiorgan autoimmunity. The patient presented with early‐onset type 1 diabetes and autoimmune hypothyroidism at 7 months. During the 7.5‐year follow‐up, she developed pseudo‐celiac enteropathy at 1 year of age and showed severe growth retardation. Whole‐exome sequencing was performed and the novel variant was further assessed by in vitro functional assays.ResultsWhole‐exome sequencing revealed a novel variant (c.1069G>A, p.Glu357Lys) in the DNA‐binding domain of STAT3. In vitro functional studies revealed that p.Glu357Lys was a GOF variant by increasing STAT3 transcriptional activity and phosphorylation. In addition, the STAT3 Glu357Lys variant caused dysregulation of insulin gene expression by enhancing transcriptional inhibition of the insulin gene enhancer binding protein factor 1 (ISL1).ConclusionIn the current study, we describe clinical manifestations and identify a novel STAT3 GOF variant (c.1069G>A) in a Chinese patient. This activating variant impairs insulin expression by increasing transcriptional inhibition of its downstream transcription factor ISL1, which could be involved in the pathogenesis of early‐onset diabetes.