bluuebunny/crossref_metadata_2025_split huggingface dataset:
<b>FACTORS AFFECTING PROFITABILITY IN FOOD AND BEVERAGE COMPANIES LISTED ON THE INDONESIA STOCK EXCHANGE</b>
Authors: De Grave Anita , Rahmadina Gita 
Published: February 2025

Penelitian ini dibuat untuk memberikan bukti empiris tentang pengaruh likuiditas, solvabilitas, aktivitas dan ukuran perusahaan terhadap profitabilitas pada perusahaan makanan dan minuman yang terdaftar di BEI periode 2015 – 2022. Likuiditas diproksikan menggunakan Current Ratio, solvabilitas diproksikan menggunakan Debt To Equity Ratio, aktivitas diproksikan menggunakan Total Assets Turnover, Ukuran Perusahaan diukur menggunakan logaritma-natural total aset dan profitabilitas diproksikan dengan Return on Assets. Jenis penelitian yang digunakan adalah kuantitatif. Teknik analisis data dalam penelitian ini adalah analisis regresi linear berganda yang dibantu dengan aplikasi SPSS versi 25. Populasi dalam penelitian ini adalah perusahaan makanan dan minuman yang terdaftar di Bursa Efek Indonesia periode 2015 – 2022 yang terdiri dari 41 perusahaan. Penentuan sampel menggunakan metode puposive sampling dengan total sampel 48 dari 6 perusahaan yang terpilih, akan tetapi penelitian ini memiliki keterbatasan yaitu data ekstrem. Hasil penelitian ini menunjukkan bahwa likuiditas berpengaruh negatif dan tidak signifikan, solvabilitas berpengaruh negatif dan signifikan terhadap profitabilitas,
aktivitas tidak berpengaruh dengan arah positif dan tidak signifikan terhadap profitabilitas, ukuran perusahaan berpengaruh negatif dan signifikan terhadap profitabilitas.
Modeling Arrhythmia in a Dish: An Open View from Human-Engineered Heart Constructs
Authors: Wang Shiya , Yang Pengcheng , Selvaraj Jonathan Nimal , Zhang Donghui 
Published: February 2025

Review
Modeling Arrhythmia in a Dish: An Open View from Human-Engineered Heart Constructs

Shiya Wang 1,†, Pengcheng Yang 1,2,†, Jonathan Nimal Selvaraj 1,* and Donghui Zhang 1,3,*
1 State Key Laboratory of Biocatalysts and Enzyme Engineering, Stem Cells and Tissue Engineering Manufacture Center, School of Life Sciences, Hubei University, Wuhan 430062, China
2 Biomanufacturing Center, Department of Mechanical Engineering, Tsinghua University, Beijing100084, China
3 Cardiovascular Research Institute, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China
* Correspondence: corresponding author:jonathannimals@hubu.edu.cn (J.N.S.); dongh.zhang@hubu.edu.cn (D.Z.)
† These authors contributed equally to this work.

Received: 26 July 2024; Revised: 29 September 2024; Accepted: 30 September 2024; Published: 6 February 2025

Abstract: Human-engineered heart constructs (hEHC), comprising cardiac organoids and engineered heart tissues, have become essential for replicating pathological and physiological mechanisms associated with cardiac development and diseases. The ongoing advancements in fabrication and culture techniques for these constructs have rendered them increasingly vital for cardiotoxicity prediction and drug efficacy evaluations. There is an escalating demand for standardized methodologies encompassing uniform fabrication, accurate disease modeling, and multidimensional phenotype assessments to facilitate a comprehensive understanding of these constructs. This review systematically examines hEHC, highlighting recent advancements in their cellular composition and functional characteristics, while stressing the necessity for thorough evaluations of significant heart disease phenotype, particularly in arrhythmia. Here, we propose a novel modular classification of cardiac model development based on specific modeling parameters and categorize existing research on in vitro functional assessment into various quantitative metrics. This classification framework provides researchers with innovative insights and strategies for personalized model design and evaluation.
Pengaruh Edukasi Penggunaan Aplikasi Tobat (Tekun Minum Obat) Terhadap Kepatuhan Minum Obat dan Kualitas Hidup Pasien TB Paru di Rumkit Tk. II Prof. dr. J.A. Latumeten
Authors: Putra Agus Dwi 
Published: February 2025

Semakin meningkatnya kejadi Tuberkolosis di dunia, Indonesia dan Kota ambon mengakibatkan dampak yang buruk dan penuruan kualitas hidup pasien Kepatuhan meminum obat sangat diperlukan pada kasus pasien TB, sehingga dibutuhkan nya aplikasi digital yang bisa mengingatkan pasien dalam konsumsi obat. Tujuan dari penelitian ini untuk mengetahui Pengaruh Edukasi Penggunaan Aplikasi TOBAT (Tekun Minum Obat) terhadap Kepatuhan Minum Obat dan Kualitas Hidup Pasien TB Paru di Rumkit Tk. II. Prof. dr. J.A. Latumeten. Desain dari penelitian ini adalah eksperimental semu (quasi experimental) dengan desain yang digunakan adalah one group pretest and posttest with control group. Populasi dalam penelitian ini adalah seluruh pasien TB Paru di Rumkit Tk.II Prof. dr. J.A. Latumeten 40 sampel yang terbagi 2 dalam kelompok intervensi dan kontrol. Dalam penelitian ini intrumen yang digunakan dalam mengukur kepatuhan minum obat pasien adalah kuesioner Morisky Medication Adherence Scale-8 (MMAS-8). Instrumen kualitas hidup WHOQOL-BREF (World Health Organization Quality of Life-BREF). Uji Statistik yang digunakan adalah uji wicolxon dan uji mann whitney. Dengan hasil yang diperoleh Terdapat perbedaan yang signifikan antara kepatuhan minum obat dan kualitas hidup pasien sebelum dan sesudah mendapatkan edukasi penggunaan aplikasi TOBAT pada pasien TB pada kelompok intervensi (p-value : 0,00). Sedangkan pada kelompok kontrol tidak ditemukan adanya perbedaan yang signifikan (p-value : 0,71) dan (p-value : 0,82). Hasil penelitian ini menunjukan bahwa terdapat perbedaan antara kepatuhan minum obat pada kelompok intervensi dan pada kelompok kontrol tidak terdapat perbedaan yang signifikan setelah diberikan edukasi penggunaan aplikasi TOBAT dan Hasil penelitian ini menunjukkan bahwa kualitas hidup pasien TB pada kelompok perlakuan mengalami peningkatan setelah dilakukan intervensi (Edukasi Penggunaan Aplikasi TOBAT) serta didapatkan hasil uji terhadap variabel kualitas hidup pasien TB dengan p 0.000 (< 0.05) artinya terdapat perbedaan kualitas hidup pasien yang signifikan antara kelompok perlakuan. Namun tidak terdapat perbedaan pada kelompok kontrol. Ketidakpatuhan terhadap pengobatan pada pasien tuberkulosis merupakan hambatan serius, ketidakpatuhan dalam pengobatan akan menyebabkan resisten terhadap obat tertentu dan menyebabkan pengobatan yang dijalani akan lebih lama, dampak dari beban psikologis pada pasien Tuberkulosis paru akan memperburuk kesehatan fisik sehingga akan menurunkan kualitas hidup pasien. Ketidakberdayaan pasien Tuberkulosis paru akan menimbulkan perubahan adaptasi pada respon psikologis, sosial, dan spiritual sehingga akan berpengaruh terhadap Quality of Life (QoL) penderitanya
Стратегии международной цепи поставок сельскохозяйственной продукции
Authors: Дун Д. 
Published: February 2025

Введение. Стратегия развития интегрированного планирования международных цепей поставок сельскохозяйственной продукции, направленная на развитие экспорта свежей российской свинины в Китай, с точки зрения логистики, основывается на технологических преимуществах транспортной логистики для предотвращения негативного воздействия внешних угроз – усиления конкурентов и показателях качества их продукции за счет сокращения транспортно-логистических издержек при прямом железнодорожном сообщении крупных центров стран, а также при сохранении параметра свежести продукции за счет современных решений интегрированного планирования цепей поставок. Материалы и методы. Для изучения и определения стратегии оптимизации цепей поставок между Россией и Китаем следует учитывать вопросы стратегического управления для достижения более практических результатов для сельскохозяйственной цепочки поставок. Для этой цели в работе применены базовые методы оценки, такие как SWOT, оценка пяти сил Портера, что позволяет сформулировать ключевые направления для конкретных стратегических шагов на базе уже существующей стратегии. Результаты исследования. В статье проведен анализ внешних и внутренних факторов, влияющих на цепь поставок экспорта российской свинины, на основе которого разработана матрица выбора стратегии планирования цепи поставок. Обсуждение и заключение. Правильно выбранная стратегия планирования цепи поставок, в свою очередь, позволит разработать эффективно функционирующую международную цепь поставок сельскохозяйственной продукции.
Introduction. The strategy of development of integrated planning of international supply chains of agricultural products, aimed at the development of export of fresh Russian pork to China, from the point of view of logistics is based on the technological advantages of transport logistics to prevent the negative impact of external threats – strengthening of competitors and quality indicators of their products by reducing transport and logistics costs with direct railway communication of major centers of the countries, as well as while maintaining the parameter of freshness of pork products. Materials and methods. In order to study and determine the supply chain optimization strategy between Russia and China, strategic management issues should be considered to achieve more practical results for the agricultural supply chain. For this purpose, the paper applies basic assessment methods such as SWOT, Porter's five forces assessment to formulate key directions for specific strategic steps based on the existing strategy. Research results. The article analyzes the external and internal factors affecting the supply chain of Russian pork exports, based on which a matrix for selecting a supply chain planning strategy was developed. Discussion and conclusion. A properly chosen supply chain planning strategy will in turn develop a well-functioning international agricultural supply chain.
Organic carbon stocks of desertification monitoring sites
Authors: Nyam-Osor Tuguldur , Tsetsegmaa Ganchudur , Akhmadi Khaulanbek 
Published: February 2025

18 cuttings and 40 samples of soil organic carbon resources of Gobisumber province were prepared, and morphological, chemical (carbonate CaCO3, reaction medium-pH humus, available potassium K2O) and physical properties (sand, silt, clay) were prepared in the soil laboratory of the Institute of Geography and Geoecology of the Mongolian Academy of Sciences, and analyzed. The reaction environment at the depth of 0-30 cm of the total section was 7.4-9.7% or weakly alkaline to strongly alkaline, and the reaction environment of Ch8 and Ch9 soils was between 6-6.5 or neutral environment. Humus content varied between 1-2.5% of the total soil. Since kastanozems and aridic Kastanozems soils of the dry steppe prevailed, when grouped into these two types, the organic carbon reserves of kastanozems soils ranged from 28.9 to 38 t ha-1, and the reserves of aridicKastanozems soils ranged from 17.7 to 27.6 t ha-1. In the field of desertification, in the experimental area, the reserves were 18.3-24.9 t ha-1 outside the fence, and 12.1-33.8 t ha-1 inside the fence. This result indicated that the level of soil fertility is improving as a result of the rehabilitation of fenced areas.

Цөлжилтийн мониторингийн талбайн органик нүүрстөрөгчийн нөөц
(Говьсүмбэр аймгийн жишээн дээр)

Говьсүмбэр аймгийн хөрсний органик нүүрстөрөгчийн нөөцийг мониторинг цэгүүдийн хүрээнд 18 зүсэлт 40 дээж бэлтгэн морфологи болон хими (карбонат CaCO3, урвалын орчин-pH ялзмаг, хөдөлгөөнт кали K2O мөн физик шинж чанарыг (элс, тоос, шаврыг) ШУА-ийн Газарзүй, геоэкологийн хүрээлэнгийн Хөрсний лабораторид шинжилгээнд хамруулсан. Нийт зүсэлтийн 0-30 см-ын гүн дэх урвалын орчин 7.4-9.7% буюу сул шүлтлэгээс хүчтэй шүлтлэг, Ч8,Ч9 хөрсний урвалын орчин 6-6.5 хооронд буюу саармаг орчинтой байна. Ялзмагийн агууламжийн хувьд нийт хөрсөнд 1-2.5%-н хооронд хэлбэлзэж байна. Хуурай хээрийн хүрэн болон цайвар хүрэн хөрсний хэв шинж давамгайлсан тул энэ хоёр төрөлд багцалж үзэхэд хүрэн хөрсний органик нүүрстөрөгчийн нөөц 28.9-38 тн га-1 , цайвар хүрэн хөрсний нөөц 17.7-27.6 тн га-1 хооронд хэлбэлзэж байсан. Цөлжилтийн сууринд туршилтын талбайд хашааны гадна талд 18.3-24.9 тн га-1, хашаан доторх 12.1-33.8 тн га-1 нөөцтэй байна. Энэ нь хашаалсан талбайн нөхөн сэргээлтийн ажлын үр дүнд хөрсний үржил шимийн түвшин сайжирч байгааг илтгэж байна.

Түлхүүр үгс: Цөлжилт, Мониторинг, Цайвар хүрэн, Органик нүүрстөрөгчийн нөөц
Conferências familiares em cuidados paliativos: uma ferramenta para comunicação de más notícias em um hospice no Distrito Federal
Authors: Santos Sara Fabrício dos , Azevedo Sarah Luiza Ferreira Lopes de , Mollo Liana Tormin , Coutinho Silvia Maria Gonçalves , Teixeira Jamila Trevizan 
Published: February 2025

Introdução: Os Cuidados Paliativos têm como objetivo melhorar a qualidade de vida de pacientes com doenças ameaçadoras à vida, por meio de uma abordagem multidimensional que inclui aspectos físicos, sociais, psicológicos e espirituais. A prática exige equipes multiprofissionais e adaptação a diferentes contextos de atuação, como hospitais gerais, ambulatórios especializados, assistência domiciliar e unidades especializadas como hóspices. Nesse contexto, a comunicação, especialmente durante as conferências familiares, é essencial para alinhar expectativas, esclarecer dúvidas e promover suporte emocional. Objetivo: compreender o impacto da comunicação entre família-paciente-equipe realizada nas conferências familiares em contexto de cuidados paliativos em um hóspice no DF, analisando sua influência na compreensão diagnóstica e prognóstica, e categorizando sua aplicação em uma unidade de saúde especializada. Método: Trata-se de um estudo qualitativo, com análise de prontuários de pacientes que internaram no Hospital de Apoio de Brasília entre os meses de março de 2023 à setembro de 2023, que houve ao menos uma conferência familiar realizada no período. Resultados: Foram encontrados 40 prontuários, desses, 52,5% são do sexo masculino; 75% para comunicar más notícias relacionadas ao prognóstico/processo ativo de morte; 27,5% visavam a desospitalização do paciente; 30% para a mediação de conflitos familiares e 10% para manejar o cerco do silêncio entre familiares e pacientes. Conclusão: Nossa pesquisa mostra a importância de uma comunicação efetiva com o paciente e seus familiares, muitas vezes realizada durante as conferências familiares, a fim de promover a humanização do cuidado, favorecer o empoderamento do paciente e família e facilitar o processo de tomada de decisões. Destacamos a importância da formação continuada dos profissionais de saúde voltada para a comunicação de más notícias, a fim de garantir uma comunicação efetiva.
Tendência temporal das hepatites virais: A, B, C e B+ C, no estado de Goiás: estudo ecológico
Authors: Paula Cácia Régia de , Cabral Karynne Borges , Prazeres Hildete Oliveira Ferreira Dos , Lima Flávio Henrique Alves de , Araújo Reila Campos Guimarães de , Silva Luiz Almeida da , Maia Ludmila Grego , Ferri Lucila Pessuti , Matos Marcos André , Barbosa Maria Alves 
Published: February 2025

Este estudo teve como objetivo, avaliar a tendência das notificações de hepatite viral A (HAV), hepatite viral B (HBV), hepatite viral C (HCV), e coinfecção de HBV + HCV. Trata-se de estudo de série temporal com dados secundários das notificações de hepatites virais: HAV, HBV, HCV e coinfecção de HBV + HCV em Goiás, entre os anos de 2010 e 2020. Os dados foram obtidos do SINAN, disponibilizados pelo DATASUS. As variáveis sociodemográficas analisadas incluíram sexo e faixa etária. As análises de tendência da série temporal foram realizadas por regressão linear pelo método de Prais-Winsten com variância robusta. Com o cálculo do coeficiente β e Erro Padrão (EP), obtido na análise de regressão, calculou-se a Annual Percent Change (APC) e respectivo Intervalo de Confiança de 95% (IC 95%). No período entre 2010 e 2020, foram notificados 674 casos de HAV, 3.403 de HBV, 2.728 de HCV e 175 casos de coinfecção de HBV + HCV, totalizando 6.980 registros. Observou-se série estacionária, para a tendência de notificações em geral para a HAV, HBV, HCV e coinfecção de HBV + HCV, com percentual anual de -2,08% (APC: -2,08 [IC: -3,93; -0,20]; p=0,058). Observou-se uma redução significativa nas taxas anuais de incidência das hepatites virais A (HAV), B (HBV), C (HCV) e da coinfecção por HBV e HCV.
Elaboración de mortero con la ceniza de cáscara de café y su incidencia en la resistencia de la compresión
Authors: Guevara-Mieles Eduardo Antonio , Rosado-Alcivar Wendy Virginia , Ruiz-Párraga Wilter Enrique 
Published: February 2025

En los últimos años han surgido problemáticas medio ambientales a nivel mundial, a causa de las emisiones de CO2 que produce la fabricación de cemento, es por ello que la industria de la construcción busca alternativas eco-amigables, dándole uso a los residuos orgánicos, para mejorar las propiedades mecánicas y estructurales del hormigón o morteros. Esta investigación se enfocó en el uso de la ceniza proveniente de la cáscara de café como un sustituto parcial del cemento, ya que la ceniza contiene propiedades puzolánicas, que favorecen la resistencia a la compresión del hormigón, los porcentajes empleados para la sustitución fueron del 5%,10% y 15%, además se prepararon muestras con arena del río Puca del cantón de Olmedo y arena de banco de la parroquia de Crucita, ambas pertenecientes a Manabí. Se realizó la comparación de los resultados obtenidos de los ensayos a los 28 días de curado, entre el mortero patrón y el mortero con sustitución parcial del cemento, el mortero elaborado fue tipo S, que tiene como resistencia 12,4 MPa como lo indica NTE INEN 2518-2010, de la investigación se determinó que con la arena del río Puca el 5%, 10% y 15% cumplen con las resistencias especificadas en la norma sin superar la muestra patrón, mientras que con la arena de banco de la parroquia de Crucita con el 5% y 10% cumplen con las resistencias especificadas en la norma. Con estos valores se pudo determinar que se puede sustituir parcialmente el cemento con la ceniza de cáscara de café en los porcentajes antes indicados.
ANALISIS BERPIKIR KRITIS PADA PERTANYAAN DISKUSI MAHASISWA PBSI FKIP UNIVERSITAS JAMBI
Authors: Yogi Deri Efri , Wibowo Imam Suwardi , Priyanto Priyanto 
Published: February 2025

This study aims to determine the ability of critical thinking in student discussion questions in the language error analysis course of PBSI FKIP Jambi University. The research method used in this study is a qualitative approach that is content analysis. Research data in the form of writings of questions and answers to student discussions in the course of language error analysis PBSI FKIP Jambi University. The data collection methods used in this study include observation and documentation. In the process, the researcher will record the questions and answers of students in the course of language error analysis of PBSI FKIP Jambi University. Researchers also collected documentation data in the form of records of student discussion questions in the course of language error analysis PBSI FKIP Jambi University. The data analysis technique used is the data analysis technique according to Miles & Huberman. In the process the data obtained will be reduced presented and conclusions drawn. The data validity test used in this research is triangulation between researchers. The results of this study are that students are able to think critically on student discussion questions in the language error analysis course of PBSI FKIP Jambi University. Critical thinking that occurs includes several categories, namely, perspective clarification, consequences and alternatives, reasons and evidence, and agreement and disagreement.
Uso de fuentes literarias por docentes en formación para el acercamiento al ser humano de distintas épocas
Authors: Hoster-Cabo Beatriz , Mena-Bernal Rosales Inmaculada , Jiménez-Jaraba M.ª Valle 
Published: February 2025

We analyse the use given by trainee teachers to literature as a source of historical information, what profile of students considers this use and what literary resources and for what purpose they are used in relation to the knowledge of historical characters. A questionnaire validated by a group of experts was used and answered by a sample of 826 students of the Degree in Primary Education from eight Spanish universities. The results show that the use of literature as a source of historical information is low in comparison with other sources, with no distinction between genders and no uniformity of response between the answers obtained in the different universities from which the sample was taken. Likewise, the low use of literary resources as a source is focused on the knowledge of writers. The resources to which they mainly turn are novels and books. Given the value of literature as a source of historical knowledge, it is proposed that it should be included in the syllabuses of future teachers for their knowledge of the Didactics of Social Sciences and historical thought and its subsequent transmission in the classroom.
Se analiza el uso que le dan los docentes en formación a la literatura como fuente de información histórica, qué perfil de estudiantes considera ese uso y qué recursos literarios y con qué fin se usan en relación con el conocimiento de personajes históricos. Se utiliza un cuestionario validado por grupo de expertos que responde una muestra de 826 estudiantes del Grado en Educación Primaria de ocho universidades españolas. Los resultados muestran que el uso de la literatura como fuente de información histórica es bajo respecto a otras fuentes, sin distinción entre géneros ni uniformidad de respuesta entre las obtenidas en las diferentes universidades de procedencia de la muestra. Asimismo, el bajo uso que realizan de los recursos literarios como fuente lo focalizan en el conocimiento de escritores. Los recursos a los que acuden principalmente son la novela y el libro. Dado el valor de la literatura como fuente de conocimiento histórico, se propone la inclusión de esta en los planes de estudio de los futuros docentes para el conocimiento de la Didáctica de la Ciencias Sociales y del pensamiento histórico y su posterior transmisión en las aulas.