bluuebunny/crossref_metadata_2025_split huggingface dataset:
ChemInform Abstract: Regio‐ and Stereospecific Synthesis of Functionalized Divinyl Selenides.
Authors: Braverman Samuel , Jana Ranjan , Cherkinsky Marina , Gottlieb Hugo E. , Sprecher Milon 
Published: February 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Convenient Synthesis of Aryl Ferrocenyl Ketone via Palladium‐Catalyzed Carbonylation Coupling.
Authors: Yang Dong , Liu Zenglu , Li Ying , Chen Baohua 
Published: February 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: New Steroids from the Soft Coral Nephthea chabrolii
Authors: Su Jui‐Hsin , Lin Fang‐Yee , Dai Chang‐Feng , Wu Yang‐Chang , Hsu Chi‐Hsin , Sheu Jyh‐Horng 
Published: February 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Alkaloids of Sida cordifolia L.
Authors: Sutradhar Ranajit K. , Rahman A. K. M. Matior , Ahmad Mesbah U. , Saha Koushik 
Published: February 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Benzofurans from the Seeds of Styrax obassia
Authors: Park Sin Young , Lee Hak‐Ju , Lee Oh‐Kyu , Kang Ha‐Young , Choi Don‐Ha , Paik Ki‐Hyon , Khan M. 
Published: February 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Design and Synthesis via Click Chemistry of 8,9‐Anhydroerythromycin A 6,9‐Hemiketal Analogues with anti‐MRSA and ‐VRE Activity.
Authors: Sugawara Akihiro , Sunazuka Toshiaki , Hirose Tomoyasu , Nagai Kenichiro , Yamaguchi Yukie , Hanaki Hideaki , Sharpless K. Barry , Omura Satoshi 
Published: February 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Total Synthesis of Streptonigrone.
Authors: Chan Bryan K. , Ciufolini Marco A. 
Published: February 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Concise Synthesis of Biologically Interesting Mollugin and Its Analogues.
Authors: Lee Yong Rok , Wang Xue , Kim Yun Mi , Shim Jae Jin , Kim Byung Nam , Han Do Hung 
Published: February 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Bio Ionic Liquids: Room Temperature Ionic Liquids Composed Wholly of Biomaterials
Authors: Fukaya Yukinobu , Iizuka Yoshiki , Sekikawa Kenta , Ohno Hiroyuki 
Published: February 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: FTICR/MS Studies of Gas‐Phase Actinide Ion Reactions: Fundamental Chemical and Physical Properties of Atomic and Molecular Actinide Ions and Neutrals
Authors: Gibson J. K. , Haire R. G. , Marcalo J. , Santos M. , Leal J. P. , Pires de Matos A. , Tyagi R. , Mrozik M. K. , Pitzer R. M. , Bursten B. E. 
Published: February 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: An Efficient Synthesis of 7‐Functionalized 7‐Deazapurine β‐D‐ or β‐L‐Ribonucleosides: Glycosylation of Pyrrolo[2,3‐d]pyrimidines with 1‐O‐Acetyl‐2,3,5‐tri‐O‐benzoyl‐D‐ or L‐ribofuranose
Authors: Peng Xiaohua , Seela Frank 
Published: February 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Efficient Synthesis of Thymidine Boranophosphoramidates Conjugated with Amino Acids
Authors: Khan Shoeb I. , Shaw Barbara Ramsay 
Published: February 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Novel Non‐Nucleoside Human Cytomegalovirus Inhibitors Based upon TSAO Nucleoside Derivatives: Structure—Activity Relationships
Authors: de Castro Sonia , Andrei Graziela , Snoeck Robert , Balzarini Jan , Camarasa Maria‐Jose , Velazquez Sonsoles 
Published: February 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Discovery of ANA975: An Oral Prodrug of the TLR‐7 Agonist Isatoribine
Authors: Xiang Alan X. , et al. et al. 
Published: February 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis of New, Base‐Modified PNA Monomers
Authors: Sipos Ferenc , Sagi Gyula 
Published: February 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: 7,5′‐O‐Dibenzylinosines: Synthesis and Studies on Their Conformational Properties
Authors: Casanova Elena , Aguado Leire , Jimeno Maria‐Luisa , Gago Federico , Camarasa Maria‐Jose , Perez‐Perez Maria‐Jesus 
Published: February 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Mechanochemistry in Heterogeneous Catalysis
Authors: Mitchenko S. A. 
Published: February 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Molecular Understanding of Re‐Based Heterogeneous Olefin Metathesis Catalysts
Authors: Salameh Alain , Leduc Anne‐Marie , Chabanas Mathieu , Basset Jean‐Marie , Coperet Christophe 
Published: February 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Glycosaminoglycans urinary excretion as a marker of the early stages of diabetic nephropathy and the disease progression
Authors: Popławska‐Kita Anna , Mierzejewska‐Iwanowska Beata , Szelachowska Małgorzata , Siewko Katarzyna , Nikołajuk Agnieszka , Kinalska Ida , Górska Maria 
Published: February 2008

AbstractBackgroundDiabetes mellitus affects the metabolism of several components of extra‐cellular matrix, including glycosaminoglycans (GAG). Alterations in the metabolism of GAG may play an important role in the development of diabetic complications.MethodsConsequently, the relationship between diabetic nephropathy and urinary GAG excretion has been estimated in 86 diabetic patients (33 type 1 diabetes mellitus (DM), 53 type 2 DM) in comparison to 30 healthy controls (Figure 1). GAG concentration in 24‐h urine samples has been determined by precipitation with cetylpyridinum chloride and potassium acetate in ethanol followed by a fluorometric test with 2‐Hexadecyl‐9H‐pyrido(4,3b)indolium Bromide.ResultsDiabetic subjects excrete significantly more GAG than the control group (66.47 mg/24 h vs 50.11 mg/24 h). A marked difference in urinary GAG excretion between diabetic patients with nephropathy (74.66 ± 7.5 mg/24 h) and without nephropathy (50.13 ± 5.37 mg/24 h) has been detected. With diabetic nephropathy, patients with a longer history of GAG excretion experience an increase. An increased urinary GAG excretion has been detected in patients with microalbuminuria or macroalbuminuria.ConclusionsIn conclusion, it can be stated that all patients with DM compared to the control group show an increase in GAG excretion independent of diabetes duration. Urinary GAG excretion positively correlates with the duration of diabetic nephropathy. The assessment of GAG excretion values may be useful for determining the early stages of diabetic nephropathy and the progression of the disease. Copyright © 2008 John Wiley & Sons, Ltd.
Mutated ATP synthase induces oxidative stress and impaired insulin secretion in β‐cells of female BHE/cdb rats
Authors: Saleh Monique C. , Fatehi‐Hassanabad Zahra , Wang Rennian , Nino‐Fong Rodolpho , Wadowska Dorota W. , Wright Glenda M. , Harper Mary‐Ellen , Chan Catherine B. 
Published: February 2008

AbstractBackgroundAdenosine triphosphate (ATP) is a critical determinant of β‐cell insulin secretion in response to glucose. BHE/cdb rats have a mutation in ATP synthase that limits ATP production, yet develop mild diabetes only with ageing. We investigated the cellular basis for reduced insulin secretion and compensatory mechanisms that mitigate the effects of the ATP synthase mutation.MethodsIn vitro β‐cell function in isolated islets and expression of key regulatory genes was compared with in vivo oral glucose tolerance and insulin sensitivity in BHE/cdb and control rats.ResultsBHE/cdb rat islets had reduced responsiveness to glucose stimulation and ATP content was 35% lower than in control islets. Oral glucose tolerance was impaired at both 21 and 43 weeks of age because of a reduction in glucose‐stimulated insulin secretion (GSIS). An increase in inducible nitric oxide synthase (INOS, 3‐fold) and manganese superoxide dismutase (MnSOD, 1.6‐fold), detection of nitrotyrosine, β‐cell apoptosis, and nucleocytoplasmic translocation of pancreas duodenum homeobox‐1 (PDX‐1) in β‐cells indicated increased oxygen radical formation. However, BHE/cdb rats partially compensated for low glucose responsiveness by increasing the number of small islets and β‐cell hypertrophy. There was also an increase in the proportion of mature insulin relative to proinsulin (PI) detected within β‐cell granules. Increased activation of AMP‐dependent kinase (AMPK)‐regulated pathways was consistent with increased oxidative stress and with induction of apoptosis and reduction of preproinsulin gene transcription.ConclusionsThe findings are consistent with impaired but partially compensated mechanisms of insulin secretion early in life, but progressive non‐compensated impairments due to oxidative stress occurs by age 43 weeks. Copyright © 2008 John Wiley & Sons, Ltd.
Methylene Spacer‐Regulated Structural Variation in Cobalt(II/III) Complexes with Bridging Acetate and Salen‐ or Salpn‐Type Schiff‐Base Ligands
Authors: Chattopadhyay Shouvik , Drew Michael G. B. , Ghosh Ashutosh 
Published: February 2008

AbstractTwo linear, trinuclear mixed‐valence complexes, [CoII{(μ‐L1)(μ‐OAc)CoIII(OAc)}2] (1) and [CoII{(μ‐L2)(μ‐OAc)CoIII(OAc)}2] (2) and two mononuclear CoIII complexes [CoIII{L3}(OAc)] (3), and [CoIII{L4}(OAc)] (4) were prepared and the molecular structures of 1, 2 and 4 elucidated on the basis of X‐ray crystallography [OAc = Acetate ion, H2L1 = H2Salen = 1,6‐bis(2‐hydroxyphenyl)‐2,5‐diazahexa‐1,5‐diene, H2L2 = H2Me2Salen = 2,7‐bis(2‐hydroxyphenyl)‐2,6‐diazaocta‐2,6‐diene, H2L3 = H2Salpn = 1,7‐bis(2‐hydroxyphenyl)‐2,6‐diazahepta‐1,6‐diene, H2L4 = H2Me2Salpn = 2,8‐bis(2‐hydroxyphenyl)‐3,7‐diazanona‐2,7‐diene]. In complexes 1 and 2, the acetate groups show both monodentate and bridging bidentate coordination modes, whereas chelating bidentate acetate is present in 4. The terminal CoIIIN2O4 centres in 1 and 2 exhibit uniform facial arrangements of both non‐bridged N2O and bridging O3 donor sets and the CoII centre is coordinated to six (four phenoxo and two acetato) oxygen atoms of the bridging ligands. The effective magnetic moment at room temperature corresponds to the presence of high‐spin CoII in both 1 and 2. The complexes 1 and 2 are thus CoIII(S = 0)–CoII(S = 3/2)–CoIII(S = 0) trimers. Complexes 3 and 4 are monomeric and diamagnetic containing low‐spin CoIII(S = 0) with chelating tetradentate Schiff base and bidentate acetate. Calculations based on DFT rationalise the formation of trinuclear or mononuclear complexes.(© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2008)
Stearoyl‐CoA desaturase: A novel control point of lipid metabolism and insulin sensitivity
Authors: Dobrzyn Pawel , Ntambi James M. , Dobrzyn Agnieszka 
Published: February 2008

AbstractStearoyl‐CoA desaturase (SCD) is a central enzyme responsible for the synthesis of monounsaturated fatty acids – mainly oleate. Recent studies have shown that SCD1 plays also a significant role in the regulation of lipid metabolism. SCD1‐deficient mice have increased energy expenditure, reduced body adiposity, increased insulin sensitivity and are resistant to diet‐induced obesity and liver steatosis. SCD1 was found to be specifically repressed during leptin‐mediated weight loss, and leptin‐deficient ob/ob mice lacking SCD1 showed markedly reduced adiposity. In addition, SCD1 deficiency completely corrects the hypometabolic phenotype and hepatic steatosis of ob/ob mice and attenuates fasting‐induced liver steatosis in PPARα‐deficient mice. Lack of SCD1 expression also improves insulin action in skeletal muscles and prevents diet‐induced hepatic insulin resistance in mice. Much evidence indicates that the direct anti‐steatotic and anti‐diabetic effects of SCD1 deficiency stem from the decreased tissue lipid content caused by enhanced fatty acid oxidation and reduced lipid synthesis. In this review, we discuss our current understanding of the role of SCD1 in insulin resistance and regulation of hepatic lipid partitioning, and test the hypothesis that pharmacological manipulation of SCD might be of benefit in the treatment of non‐alcoholic fatty liver disease and in the prevention of diabetes.
Synthesis of Poly(arylenevinylene)s with Fluorinated Vinylene Units
Authors: Babudri Francesco , Cardone Antonio , Farinola Gianluca M. , Martinelli Carmela , Mendichi Raniero , Naso Francesco , Striccoli Marinella 
Published: February 2008

AbstractPoly(arylenevinylene) polymers bearing fluorine atoms in the vinylene units were obtained by a Stille cross‐coupling reaction of (E)‐(1,2‐difluoro‐1,2‐ethenediyl)bis(tributylstannane) with diiodoaryl derivatives. The introduction of fluorine atoms on the double bond of the stannane leads to polymers with relatively high molecular weights. Furthermore, the presence of fluorinated vinylene units changes the optical properties of the polymers and shifts the emission towards the blue region of the visible spectrum. A fluorinated analogue of MEH‐PPV was obtained, and it shows photoluminescence that is considerably blueshifted, also in the solid state, relative to that found for nonfluorinated MEH‐PPV and to other PPVs with fluorinated double bonds.(© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2008)
Thermo‐Solvatochromism of Merocyanine Polarity Probes – What Are the Consequences of Increasing Probe Lipophilicity through Annelation? (Eur. J. Org. Chem. 7/2008)
Authors: Martins Clarissa T. , Lima Michelle S. , Bastos Erick L. , El Seoud Omar A. 
Published: February 2008

AbstractThe cover picture shows the quinonoid and zwitterionic limiting formulas of the solvatochromic probe MeAMBr2 [(E)‐2,6‐dibromo‐2‐(1‐methylacridinium‐4‐yl)ethenyl phenolate]. The solvatochromic behavior is influenced by the solvent‐dependent contributions of the two limiting formulas to the ground and excited states of the probe. Details are discussed in the article by O. A. El Seoud et al. on p. 1165 ff. The artwork for the cover picture was prepared by E. L. Bastos.
An Amperometric Biosensor for trans‐Resveratrol Determination in Aqueous Solutions by Means of Carbon Paste Electrodes Modified with Peroxidase Basic Isoenzymes from Brassica Napus
Authors: Granero Adrián Marcelo , Fernández Héctor , Agostini Elizabeth , Zón María Alicia 
Published: February 2008

AbstractThe catalytic properties of peroxidase basic isoenzymes (PBI's) from Brassica napus towards trans‐resveratrol (t‐Res) oxidation were demonstrated by the first time by conventional UV‐visible spectroscopic measurements. The enzymatic reaction rate was studied under different experimental conditions and the kinetics parameters were determined. An amperometric biosensor based on Brassica napus PBI's to determine t‐Res is also proposed by the first time. The method employs a dialysis membrane covered, PBI's entrapped and ferrocene (Fc)‐embedded carbon paste electrode (PBI's‐Fc‐CP) and is based on the fact that the decreased amount of H2O2 produced by the action of PBI's is proportional to the oxidised amount of t‐Res in the solution. Comparative amperometric experiments showed that, in spite of PBI's activity was much lower than commercial horseradish peroxidase (HRP) activity, t‐Res was a much better substrate for PBI's biosensors than those biosensors constructed by using HRP. The PBI's‐Fc‐CP biosensors showed a very good stability during at least twenty days. The reproducibility and the repeatability were 4.5% and 8.3%, respectively, showing a good biosensor performance. The calibration curve was linear in the t‐Res concentration (ct‐Res) range from 1×10−6 to 2.5×10−5 M, with a sensibility of (2.31±0.05)×106 nA M−1. The lowest ct‐Res value measured experimentally for a signal to noise ratio of 3 : 1 was 0.83 μM.
Advances in Interfacial Design for Electrochemical Biosensors and Sensors: Aryl Diazonium Salts for Modifying Carbon and Metal Electrodes
Authors: Gooding J. Justin 
Published: February 2008

AbstractA high degree of control over the modification of electrode surfaces is required for many sensing applications. This critical review briefly outlines some of the considerations for interfacial design in amperometric sensors and discusses some of advantages and disadvantages of alkanethiol modified metal electrodes for such applications before concentrating on the modification of electrodes surfaces using aryl diazonium salts. The pros and cons of this chemistry, and the application of aryl diazonium salts for sensing on carbon electrodes is reviewed before recent advances in using this chemistry for modifying metal electrodes are presented.
Chip Based Electroanalytical Systems for Cell Analysis
Authors: Spegel Christer , Heiskanen Arto , Skjolding Lars Henrik Dæhli , Emnéus Jenny 
Published: February 2008

AbstractThis review with 239 references has as its aim to give the reader an introduction to the kinds of methods used for developing microchip based electrode systems as well as to cover the existing literature on electroanalytical systems where microchips play a crucial role for ‘nondestructive’ measurements of processes related to living cells, i.e., systems without lysing the cells. The focus is on chip based amperometric and impedimetric cell analysis systems where measurements utilizing solely carbon fiber microelectrodes (CFME) and other nonchip electrode formats, such as CFME for exocytosis studies and scanning electrochemical microscopy (SECM) studies of living cells have been omitted. Included is also a discussion about some future and emerging nano tools and considerations that might have an impact on the future of “nondestructive” chip based electroanalysis of living cells.
Aroma‐active compounds of American, French, Hungarian and Russian oak woods, studied by GC–MS and GC–O
Authors: Díaz‐Maroto M. Consuelo , Guchu Emilia , Castro‐Vázquez Lucía , de Torres Carmen , Pérez‐Coello M. Soledad 
Published: February 2008

AbstractGas chromatography–mass spectrometry (GC–MS) and gas chromatography–olfactometry (GC–O) were used to study aroma‐active compounds in extracts of American, French, Hungarian and Russian oak woods. Compounds that presented high odour intensities for the non‐toasted oak woods were guaiacol, hexanal, trans‐2‐nonenal, trans‐oak lactone, cis‐oak lactone, eugenol, vanillin and trans‐isoeugenol, whilst the same compounds, in addition to furfural, 4‐methylguaiacol and cis‐isoeugenol, proved important in the toasted oaks. Like the oak lactones, cis‐ and trans‐isoeugenol presented woody/oak odours, particularly in the toasted samples. For Hungarian and Russian samples, both characterized by their lower content of oak lactones, trans‐ and cis‐isoeugenol presented higher odour intensities. For this reason, samples of low oak lactone concentrations, such as Hungarian and Russian oak woods, but also containing isoeugenols, can impart woody/oak odours to wines. Copyright © 2008 John Wiley & Sons, Ltd.