bluuebunny/crossref_metadata_2025_split huggingface dataset:
ChemInform Abstract: Exploiting Structure—Activity Relationships in Docking.
Authors: Sullivan David C. , Martin Eric J. 
Published: June 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Docking Ligands into Flexible and Solvated Macromolecules. Part 2. Development and Application of FITTED 1.5 to the Virtual Screening of Potential HCV Polymerase Inhibitors.
Authors: Corbeil Christopher R. , Englebienne Pablo , Yannopoulos Constantin G. , Chan Laval , Das Sanjoy K. , Bilimoria Darius , L'Heureux Lucille , Moitessier Nicolas 
Published: June 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Enhancement of Ordinal CoMFA by Ridge Logistic Partial Least Squares.
Authors: Ohgaru Takanori , Shimizu Ryo , Okamoto Kosuke , Kawashita Norihito , Kawase Masaya , Shirakuni Yuko , Nishikiori Rika , Takagi Tatsuya 
Published: June 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: The Nb—Ni—Ti (Niobium—Nickel—Titanium) System‐update
Authors: Gupta K. P. 
Published: June 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Al—Nd—Ti (Aluminum—Neodymium—Titanium)
Authors: Raghavan V. 
Published: June 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Development of a New Production Process for N‐Vinyl‐2‐pyrrolidone
Authors: Shimasaki Yuuji , Yano Hitoshi , Sugiura Hideto , Kambe Hideyuki 
Published: June 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Catalytic C—C, C—N, and C—O Ullmann‐Type Coupling Reactions: Copper Makes a Difference
Authors: Monnier Florian , Taillefer Marc 
Published: June 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Aryl and 1,3‐Dioxoindanyl Derivatives of Azoles and Azines
Authors: Garnovskii A. D. , Sennikova E. V. 
Published: June 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Recent Advances in Enantioselective [2 + 2 + 2] Cycloaddition.
Authors: Shibata Takanori , Tsuchikama Kyoji 
Published: June 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Chiral Memory: Induction, Amplification, and Switching in Porphyrin Assemblies
Authors: Rosaria Lauceri , D'Urso Alessandro , Mammana Angela , Purrello Roberto 
Published: June 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: A Novel RNA Synthetic Method with a 2′‐O‐(2‐Cyanoethoxymethyl) Protecting Group
Authors: Shiba Yoshinobu , Kitagawa Hidetoshi , Masutomi Yutaka , Ishiyama Kouichi , Ohgi Tadaaki , Yano Junichi 
Published: June 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis of 3′‐(Ureido)adenosine Derivatives and Their High Binding Affinity at the Mutant A3 Adenosine Receptor
Authors: Kim Ae Yil , Kim Hea Ok , Kim Myoung Jung , Chun Moon Woo , Lee Kang Man , Jacobson Kenneth A. , Jeong Lak Shin 
Published: June 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Molecular Modeling of the Biologically Active Alkaloids
Authors: Tareq Mahmud , Khan Hassan 
Published: June 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Chemistry and Biological Activity of Tetrahydrocannabinol and Its Derivatives
Authors: Flemming T. , Muntendam R. , Steup C. , Kayser Oliver 
Published: June 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Polymer‐Induced Transient Pores in Lipid Membranes
Authors: Binder Wolfgang H. 
Published: June 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
The role of π‐acidic and π‐basic chiral stationary phases in the high‐performance liquid chromatographic enantioseparation of unusual β‐amino acids
Authors: Ilisz István , Berkecz Róbert , Forró Enikő , Fülöp Ferenc , Armstrong Daniel W. , Péter Antal 
Published: June 2008

AbstractThe application of 3,5‐dimethylphenyl‐carbamoylated‐β‐cyclodextrin (Cyclobond I 2000 DMP) and 2,6‐dinitro‐4‐trifluoromethylphenyl‐ether‐β‐cyclodextrin‐based (Cyclobond DNP) chiral stationary phases for the high‐performance liquid chromatographic enantioseparation of unusual β‐amino acids is reported. The investigated amino acids were saturated or unsaturated alicyclic β‐3‐homo‐amino acids and bicyclic β‐amino acids. Prior to chromatographic analyses, all amino acids were transformed to N‐3,5‐dinitrobenzoyl‐ or N‐3,5‐dimethylbenzoyl form to ensure a π‐acidic or π‐basic function and to enhance the π‐acidic‐π‐basic interactions between analytes and chiral selectors. Chromatographic results are given as retention, separation and resolution factors. The chromatographic conditions were varied to achieve optimal separation. The sequence of elution of the enantiomers was determined in some cases. Chirality, 2009. © 2008 Wiley‐Liss, Inc.
Enantiomers of a nonylphenol isomer: Absolute configurations and estrogenic potencies
Authors: Zhang Haifeng , Oppel Iris M. , Spiteller Michael , Guenther Klaus , Boehmler Gabriele , Zuehlke Sebastian 
Published: June 2008

AbstractEnantiomers of 4‐(1,1,2‐trimethylhexyl)phenol, a chiral isomer of the endocrine disrupting chemical nonylphenol, have been resolved and isolated by preparative chiral HPLC. The absolute configurations of the enantiomers were then determined by an X‐ray crystallographic study of the (−)‐camphanoyl derivative of the first eluted enantiomer NP35E1. The first enantiomer (NP35E1) and the second enantiomer (NP35E2) eluted were found to have the S and R absolute configurations, respectively. The estrogenic potencies of the S and R enantiomers were tested by the E‐screen assay. A slight difference was observed in the relative proliferative effect between the S enantiomer and R enantiomer in the E‐screen assay. Chirality, 2009. © 2008 Wiley‐Liss, Inc.
Cellulose tris(3,5‐dimethylphenylcarbamate)‐based chiral stationary phases as effective tools for enantioselective HPLC separation of structurally different disubstituted binaphthyls
Authors: Loukotková Lucie , Rambousková Milena , Bosáková Zuzana , Tesařová Eva 
Published: June 2008

AbstractCellulose tris(3,5‐dimethylphenylcarbamate)‐based chiral stationary phases (CSPs) were used for a study of the HPLC retention and enantioseparation behavior of 2,2′‐disubstituted or 3,2,2′‐trisubstituted 1,1′‐binaphthyls and 8,3′‐disubstituted 1,2′‐binaphthyls. The effects of the mobile phase composition in normal‐ (NP) and reversed‐phase (RP) separation modes were investigated. The NP mobile phases contained n‐hexane and propane‐2‐ol at various volume ratios, the RP ones were obtained by mixing acetonitrile with water or a 20 mM phosphate buffer of pH 6.0 or 3.0. The RP separation mode has been found more suitable for enantioresolution of most of the analytes. The best enantioseparation of 2,2′‐diacetyl‐1,1′‐binaphthyl, 2‐hydroxy‐2′‐(phenylamino)‐1,1′‐binaphthyl‐3‐carboxylic acid and 2‐amino‐2′‐hydroxy‐1,1′‐binaphthyl‐3‐carboxylic acid was obtained in the mobile phase of ACN/20 mM phosphate buffer, pH 3.0, 40/60 (v/v), whereas N‐(2′‐hydroxy‐1,1′‐binaphthyl‐2‐yl)acetamide, N‐(3′‐methoxy‐1,2′‐binaphthyl‐8‐yl)acetamide, and N‐(3′‐hydroxy‐1,2′‐binaphthyl‐8‐yl)acetamide yielded better results in ACN/water at the same v/v ratio. The analyte–CSP interaction mechanism was found to be temperature independent but the enantioresolution improved at an elevated temperature. The mechanism of the enantioselective discrimination is discussed on the basis of the thermodynamic parameters obtained. Semi‐preparative separation conditions have been proposed for 2‐amino‐2′‐hydroxy‐1,1′‐binaphthyl‐3‐carboxylic acid, N‐(3′‐methoxy‐1,2′‐binaphthyl‐8‐yl)acetamide, and N‐(3′‐hydroxy‐1,2′‐binaphthyl‐8‐yl)acetamide. Chirality, 2008. © 2008 Wiley‐Liss, Inc.
Direct screening of chiral discrimination abilities of chiral hosts using mass spectrometry
Authors: Shizuma Motohiro , Adachi Hiroshi , Ono Daisuke , Sato Hirofumi , Nakamura Masaki 
Published: June 2008

AbstractA simultaneous estimation of the chiral discrimination abilities of several chiral hosts was demonstrated on the basis of one mass spectrum. The chiral host mixture, including H1, H2, H3 ···, and Hm (m: number of hosts) was prepared by etherification of several chiral alcohols with bistosylate of diethylene glycol. An equimolar mixture of a deuterium‐labeled (S)‐ and unlabeled (R)‐enantiomer of an amino acid isopropyl ester hydrochloride (GS‐dn+Cl− and GR+Cl−, n: number of deuterium atoms) was added to the chiral host mixture, and the FAB mass spectrum was measured to evaluate the chiral discrimination ability of each host in the mixture without isolation. The chiral discrimination ability of each host toward the guest is represented by the relative peak intensity of the diastereomeric complex ion pair, I(Hm + GR(+/I(Hm + GS‐dn)+ (=IR/IS‐dn value). Several new hosts showed good chiral discrimination toward the guest. Chirality, 2009. © 2008 Wiley‐Liss, Inc.
A rational approach to predict and modulate stereolability of chiral α substituted ketones
Authors: Cirilli Roberto , Costi Roberta , Di Santo Roberto , Gasparrini Francesco , La Torre Francesco , Pierini Marco , Siani Gabriella 
Published: June 2008

AbstractAn effective strategy to assess and modulate the stereolability of chiral α substituted ketones (CαSKs) is presented. The tendency of CαSKs to retain or change their configuration in water is analyzed as a function of thermodynamic proton‐release attitude of α asymmetric atoms inside the structures by linear Brønsted correlations. A molecular modeling procedure was developed to analyze and suggest chemical modifications of CαSKs in view to obtain the desired grade of stereochemical stability. The approach was employed to predict the tendency to enantiomerize in water of two ketones (1 and 2) endowed with inhibitory activity against monoamine oxidases (MAOs) and the results were confirmed by experimental kinetics measurements performed in organic medium. As a demonstration of practical potentialities of the approach, four new structures, conceived as simple chemical modifications of 1 and 2, were designed to improve/reduce the stereostability grade of the starting anti‐MAO ketones. The possibility to extend easily the procedure to other classes of CH acids appears of interest. Chirality, 2009. © 2008 Wiley‐Liss, Inc.
Biphasic recognition chiral extraction: A novel method for separation of mandelic acid enantiomers
Authors: Tang Kewen , Yi Jianmin , Huang Kelong , Zhang Guoli 
Published: June 2008

AbstractThis article reports a new chiral separation method—biphasic recognition chiral extraction for the separation of mandelic acid enantiomers. Distribution behavior of mandelic acid enantiomers was studied in the extraction system with O,O′‐di‐benzoyl‐(2S,3S)‐4‐toluoyl‐tartaric acid (D‐(+)‐DTTA) in organic phase and β‐CD derivatives in aqueous phase, and the influence of the types and concentrations of extractants and pH on extraction efficiency was investigated. Hydroxypropyl‐β‐cyclodextrin (HP‐β‐CD), hydroxyethyl‐β‐cyclodextrin (HE‐β‐CD), and methyl‐β‐cyclodextrin (Me‐β‐CD) have stronger recognition abilities for S‐mandelic acid than those for R‐mandelic acid, among which HP‐β‐CD has the strongest ability. D‐(+)‐DTTA preferentially recognizes R‐mandelic acid. pH and the concentrations of extractants have great effects on chiral separation ability. A high enantioseparation efficiency with a maximum enantioselectivity of 1.527 is obtained at pH of 2.7 and the ratio of 2:1 of [D‐(+)‐DTTA] to [HP‐β‐CD]. The obtained results indicate that the biphasic recognition chiral extraction is of stronger chiral separation ability than the monophasic recognition chiral extraction. It may be very helpful to optimize the extraction systems and realize the large‐scale production of pure enantiomers. Chirality, 2009. © 2008 Wiley‐Liss, Inc.
Trans‐admittance control for eliminating the temperature effect of piezoelectric transformer in the CCFL backlight module
Authors: Lo Yu‐Kang , Pai Kai‐Jun , Chiu Huang‐Jen 
Published: June 2008

AbstractA half‐bridge (HB) resonant inverter for driving a cold cathode fluorescent lamp (CCFL) backlight module with a piezoelectric transformer (PT) is analyzed in this paper. The resonant inductance of the HB inverter is expressed as a function of the load current, the load resistance and the PT circuit parameters. Also, the trans‐admittance of the PT‐CCFL combination network is measured to track the operating frequency for the HB resonant inverter, which may be varied due to the temperature rise of PT. The lamp driving current and power can thus remain almost constant in a wide temperature range. Experiments show that the observed results match the theoretical analyses. Copyright © 2008 John Wiley & Sons, Ltd.
Production, liquidity, and futures price dynamics
Authors: Wong Kit Pong 
Published: June 2008

AbstractThis study examines the optimal design of a futures hedge program for the competitive firm under output price uncertainty. All futures contracts are unbiased and marked to market in that they require interim cash settlement of gains and losses. The futures price dynamics follows a first‐order autoregression with a random walk serving as a special case. The firm's futures hedge program is constituted of an endogenous provision for premature termination, which depends on how the futures prices are autocorrelated. Succinctly, the firm voluntarily commits to premature liquidation of its futures position on which the interim loss incurred exceeds a predetermined threshold level if the futures prices are positively autocorrelated. In this case, the liquidity constrained firm optimally opts for an over‐hedge if its preferences exhibit either constant or increasing absolute risk aversion. If the futures prices are uncorrelated or negatively autocorrelated, the firm prefers to be liquidity unconstrained and thus adopts a full‐hedge to completely eliminate the output price risk. © 2008 Wiley Periodicals, Inc. Jrl Fut Mark 28:749–762, 2008
Do tax‐exempt yields adjust slowly to substantial changes in taxable yields?
Authors: Dudney Donna , Geppert John 
Published: June 2008

AbstractThis paper examines the profitability of two futures trading strategies: a municipal bond futures contract strategy and a spread strategy consisting of a municipal bond futures contract and a Treasury bond futures contract. Both strategies are designed to exploit a slow municipal yield adjustment following changes in Treasury yields. We find economically significant profits to both strategies. Average holding period returns per trade for both strategies tend to increase with the magnitude of the Treasury yield change. Profit distributions associated with various Treasury yield change thresholds tend to be positively skewed, and median profits are significantly lower than average profits. The profitability results are consistent with slow municipal yield adjustments. © 2008 Wiley Periodicals, Inc. Jrl Fut Mark 28:763–789, 2008
Nonparametric American option pricing
Authors: Alcock Jamie , Carmichael Trent 
Published: June 2008

AbstractA nonparametric method is introduced to accurately price American‐style contingent claims. This method uses only historical stock price data, not option price data, to generate the American option price. The accuracy of this method is tested in a controlled experimental environment under both Black, F and Scholes, M (1973) and Heston, S (1993) assumptions, and an error‐metric analysis is performed. These numerical experiments demonstrate that this method is an accurate and precise method of pricing American options under a variety of market conditions. © 2008 Wiley Periodicals, Inc. Jrl Fut Mark 28:717–748, 2008
HDD and CDD option pricing with market price of weather risk for Taiwan
Authors: Huang Hung‐Hsi , Shiu Yung‐Ming , Lin Pei‐Syun 
Published: June 2008

AbstractThis study extends the long‐term temperature model proposed by Alaton et al. (2002) by taking into account ARCH/GARCH effects to reflect the clustering of volatility in temperature. The fixed variance model and the ARCH model are estimated using Taiwan weather data from 1974 through 2003. The results show that for HDD/CDD the call price is higher under ARCH‐effects variance than under fixed variance, while the put price is lower. Although different pricing methods are employed in pricing weather options, the effects of mean and standard deviation on option prices are mathematically proved to be the same as those in pricing traditional financial derivatives using the Black‐Scholes formula. © 2008 Wiley Periodicals, Inc. Jrl Fut Mark 28:790–814, 2008
Characterization of amplicons in neuroblastoma: High‐resolution mapping using DNA microarrays, relationship with outcome, and identification of overexpressed genes
Authors: Fix Anne , Lucchesi Carlo , Ribeiro Agnès , Lequin Delphine , Pierron Gaëlle , Schleiermacher Gudrun , Delattre Olivier , Janoueix‐Lerosey Isabelle 
Published: June 2008

AbstractSomatically acquired chromosomal imbalances are a key feature of neuroblastoma, a heterogeneous pediatric solid tumor. Among these alterations, genomic amplification targeting theMYCNoncogene and observed in about 25–30% of the cases, strongly correlates with advanced stage and poor outcome. In this work, we have used BAC and SNP arrays as well as gene expression arrays to characterize amplifications in neuroblastoma. Eighty‐eight distinct BACs defining high‐level amplification events were identified in 65 samples, including 43 tumors and 22 cell lines. Although the highest recurrence was observed on chromosome 2, clones on chromosomes 8, 12, 16, and 17 also revealed genomic amplification in several samples. A detailed analysis of the 2p22‐2p25MYCNcontaining region indicated highly complex patterns in a number of cases. Coamplifications involvingMYCNand other regions were explored by FISH in three cell lines. High‐resolution arrays then allowed us to further refine the mapping of 25 amplicons in 19 samples, either reducing the size of a single continuous amplicon or increasing the complexity by highlighting multiple noncontiguous regions of amplification. Combined analysis of gene expression profiling and array‐CGH data indicated that 12 to 25% of the genes that are targeted by genomic amplification are actually over‐expressed in tumor cells, several of them having already been implicated in cancer. Finally, our results suggest that the presence of amplicons localized outside of chromosome 2, in addition toMYCNamplification, may be linked to a particularly severe outcome in neuroblastoma patients. © 2008 Wiley‐Liss, Inc.
Microarray‐based DNA profiling to study genomic aberrations
Authors: Waddell Nic 
Published: June 2008

AbstractHigh throughput microarrays were initially developed to analyse the expression of many RNA transcripts in parallel. The technology has since been adapted to a variety of applications, one of which is the analysis of the genome to study DNA dosage and sequence content. Advances in microarray fabrication and completion of large‐scale genome sequencing projects have enabled the rapid development of affordable array‐based methods for high‐resolution genome‐wide assessment of DNA alterations. This review will describe the evolution of microarray assays to study genomic aberrations and will highlight how they have enabled researchers to gain insight into the biology of human diseases and how they will benefit research in the future. © 2008 IUBMB IUBMB Life, 60(7): 437–440, 2008