bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Influence of Perioperative Enoxaparin on Bleeding After TORS Oropharyngectomy
Authors: Dewey John , Shaikh Noah , Al-Asadi Zayd , Turner Meghan 
Published: March 2024

Abstract

Objective: Perioperative enoxaparin is often avoided in patients undergoing trans-oral robotic (TORS) oropharyngectomy. Our goal was to quantify the risk of postoperative hemorrhage (POH) in patients receiving enoxaparin after TORS oropharyngectomy.
Study Design: Retrospective database cohort study.
Setting: 76 separate healthcare organizations.
Methods: The TriNetX electronic database was queried for patients with OPSCC who underwent TORS oropharyngectomy. Propensity-score matching was used to create two cohorts, one receiving and one not receiving perioperative enoxaparin. Outcome measures were the POH rate within 7 days of surgery (“primary”) and POH rate within 7-30 days of surgery (“secondary”).
Results: 973 patients undergoing TORS for OPSCC were identified, 362 of which received perioperative enoxaparin. One-to-one propensity score matching resulted in 276 patients per cohort. After matching, the primary POH rates between patients receiving and not receiving enoxaparin were 5.43% vs. 3.62% (OR 1.529, 95% CI 0.675 to 3.465). The secondary POH rates between those receiving and not receiving enoxaparin were 6.88% vs. 3.62% (OR 1.967, 95% CI 0.897 to 4.310). The number needed to harm (NNH) with perioperative enoxaparin use for primary and secondary POH after TORS was 55 and 30, respectively.
Conclusion: While not statistically significant, the use of perioperative enoxaparin after TORS is associated with increased odds of POH with a NNH of 55 and 30 for primary and secondary POH. For patients undergoing TORS, enoxaparin use requires careful weighing of the risks and benefits.
The effect of altitude above sea level on some structural characteristics, dynamics and diversity on Zagros forests in western Iran
Authors: Haidari Reza Hossein , pour Mohsen Javanmiri 
Published: March 2024

Abstract
Ecological conditions, such as environmental gradients, can affect the structural features and diversity of forests situated in altitude gradients. A study was conducted to examine the impact of altitude above sea level on certain structural features and diversity in Zagros forests in the Ghalajeh area of Kermanshah province. To analyze the effects of diversity on structural and habitat characteristics and their changes in different altitude gradients, eight sites were selected in four altitude ranges from sea level: 1200–1475 meters (low-land), 1475–1750 meters (low to mid-altitude), 1750–2025 meters (mid to high-altitude), and 2025–2300 meters (high-land), identified in both northern and southern slopes. In each site, three sample plots were chosen as replicates, and within each sample plot, all necessary characteristics of trees were measured. The results showed that with increasing altitude above sea level, the number and frequency of tree species increased, while the density of Iranian oak trees decreased. Species such as Almond tree (Prunus elaeagrifolia), Italian Honeysuckle (Lonicera nummulariifolia), and Maple tree (Acer monospessulanum) were predominantly present at higher altitudes. However, the presence of trees initially increased (in the mid-altitude elevation), then decreased (in the highland elevation) with increasing altitude, although this attribute was nearly equal in the lowland elevation in both northern and southern slopes. The study also found statistically significant differences (p < 0.05) in variables such as tree diameter at breast height, tree height, and tree dieback levels across different altitudes above sea level. These results are beneficial in addressing ecological issues such as forest conservation and management, as well as assessing favorable environmental conditions, providing insights to predict future trends based on these findings.
Modelling methodology for the analysis of local government debt compliance
Authors: Antão Mário A. , Santos Paula , Trigueiros Duarte 
Published: March 2024

Abstract

To mitigate the difficulty of analysing local government debt, this article uses a methodology that makes statistical models more suitable for use with financial data, improving their reliability and ease of construction. The article illustrates the application of this methodology by identifying the factors that explain the unintelligible variation in Portuguese local government debt, showing how to identify which local governments have the most unpredictable variation in debt, and how to construct reliable and easy-to-use municipal Z-scores.
JEL Classification: C18, C21, C51, C52, C58, H68, H74, M48
Necrotizing Fasciitis: Treatment Concepts &amp; Clinical Outcomes – An Institutional Experience.
Authors: Raveendranadh Ajay , Prasad S S , Viswanath Vivek 
Published: March 2024

Abstract

BACKGROUND:
A severe infection of the skin and soft tissues, necrotizing fasciitis (NF), spreads quickly along the deep fascia. This study aimed to characterize the clinicopathological features and analyze the bacteria implicated in antibiotic sensitivity, surgical management, and diagnostic accuracy of the Laboratory risk indicator for Necrotizing Fasciitis (LRINEC) score for Necrotizing Soft Tissue Infection (NSTI)
METHODS:
This single-center prospective observational study was conducted in the Department of General Surgery, Kasturba Medical College, Manipal, with 171 proven cases of NSTI between 2019 and 2021. Clinico-demographic data and laboratory investigation values were collected at two time points (at admission and 72 hours after admission). Imaging data, LRINEC score, culture results, and antibiotic sensitivity were recorded. Appropriate descriptive and analytical statistics were used for the statistical analysis.
RESULTS:
Of the 171 patients, 150 were male (87.7%). The mean age was 57.6 ± 13.1 years. The presenting features in all the cases were pain, swelling, and fever. Diabetes mellitus (DM) is the most common comorbidity. The lower extremities were the most commonly affected sites. Streptococcus pyogenes showed significant growth in 25.41% of the samples. Ceftriaxone sensitivity was seen in 41/141. A score of ≥ 8 was obtained n 118/171 (69%) patients, suggesting a higher severity and significant risk for NSTI. The Area Under the Curve of Receiver Operating characteristic Curve (ROC) for establishing diagnostic accuracy for LRINEC was 0.694. Mortality was significantly higher in the patients with higher LRINEC scores and elevated procalcitonin. The mortality rate was higher in patients who underwent surgery within 12 hours.
CONCLUSION:
Necrotizing fasciitis is a soft tissue infection with a high mortality rate. The clinical features and determinants of mortality in patients with NF are highlighted in this study. At the outset, a high index of suspicion was critical. Using prognostic evaluation techniques in daily clinical practice will assist medical professionals in providing adequate on-time care and significantly lowering mortality. Delay in surgical intervention after admission is one of the most important determinants of mortality and morbidity.
Single and Multi-Lead ECG Heartbeat Classification Using XGBoost on Pre-trained CNN Feature Layer
Authors: Kancharla Naveen Kumar , V Brindha 
Published: March 2024

Abstract
Electrocardiogram (ECG) is a common tool used in technology-assisted systems to help spot heart rhythm problems. Doctors rely on it to identify and understand any irregularities in the heart's activity. Therefore, making the process of analyzing ECG heartbeats automatic is crucial for diagnosing heart conditions effectively. This proposed work introduces a groundbreaking approach for analyzing electrocardiogram (ECG) signals, essential for diagnosing heart conditions. It uniquely combines XGBoost, a potent predictive model, with the capabilities of pretrained convolutional neural networks (CNNs) for detecting features in ECG data. Applied to both single and multi-lead ECG datasets, specifically MIT-BIH and PTB-XL, this approach offers a straightforward yet highly effective way to diagnose cardio vascular diseases.
Compared with traditional models like Decision Trees, Random Forest, and others, the proposed method significantly outperforms, achieving accuracies of 95.8% for single-lead and 97% for multi-lead signals. This innovation excels in precision and reduces the complexity and computational needs, showcasing a significant leap forward in efficient and accurate ECG classification.
in silico Computational Studies of phenolic compounds from Pinaropappus roseus Less leaves extract against BCL-2 and BCL-XL proteins Associated with Cancer Cell Survival and Resistance
Authors: Tejeda-Orjuela Juan Camilo , Chaparro-Hernández Irene , Mendez-Lagunas Lilia Leticia , Sandoval-Torres Sadith , Rodríguez-Ramírez Juan , Barriada-Bernal Luis Gerardo 
Published: March 2024

Abstract
The aim of this study was to investigate the phenolic compound from Pinaropappus roseus, and its human breast anticancer properties. The phenolic molecules were isolated from the aqua-ethanoic extract isolated from the leaves of P. roseus by solid-phase extraction (SPE). The total phenolic content was determined by the Folin-Ciocalteu technique. The profile of phenolic compounds was analyzed by mass spectrometry (LC-ESI-MS2). The quantification of phenolic molecules identified by mass spectrometry was carried out by UV-spectrophotometry (LC-PDA). The in vitro cytotoxicity assay was carried on MCF-7 and HMEC cell lines using the MTT assay method. The docking simulation was carried out in anti-apoptotic proteins, Bcl-2 and Bcl-xL. Six phenolic compounds were identified of which the apigenin (37.5 mgCAEgdb−1) was the most abundant compound. In the in vitro anti-cancer assay, the IC50 for the MCF-7 cells was of 426.15 µg gdb−1 at 24h and 297.40 µg gdb−1 at 48 h for the maximum evaluated phenolic extract concentration. The rutin and the chlorogenic acid showed the higher binding energies in the docking simulation for the active sites of the Bcl-2 and Bcl-xL proteins respectively. The phenolic compounds of P. roseus have cytotoxic activity against human breast cancer (MCF-7 cell line) and a low cytotoxic activity against normal human epithelial cells (HMEC cell line).These results suggest that the phenolic extract of P. roseus may have therapeutic potential against human cancer pathologies.
Durable antibacterial cotton fabrics with good performance enabled by quaternary ammonium salts
Authors: Ding Qi , Liu Jiang-Long , Liu Yan-Yan , He Wen-Zhan , Zhang Lin , Xu Ying-Jun 
Published: March 2024

Abstract

For addressing the issue of limited durable antibacterial cotton fabric, this study developed and synthesized quaternary ammonium salt antimicrobial agents. The chemical structure was analyzed by FTIR and 1H NMR. The cotton fabric was subjected to surface modification techniques, such as pad-dry-cure, following the careful selection of appropriate quaternary ammonium salt. The chemical state and surface morphology were evaluated through XPS and SEM. Furthermore, the cotton fabric underwent comprehensive assessments, which included antibacterial testing, laundering cycle testing, evaluation of mechanical properties, and analysis of comfort performance. The results demonstrated that the treated cotton fabric achieved a high bacteriostatic and fungistatic rate of 99.99%, 87.5%, and 99.99% against S. aureus, E. coli, and C. albicans respectively even after 50 laundering cycles, while maintaining exceptional antibacterial effectiveness and laundering durability due to the formation of covalent bonds with the cotton fabric. The treated cotton fabric met AAA grade standards for antibacterial rate without causing any significant decline in mechanical properties. Furthermore, enhancements in hydrophilicity, softness, and wrinkle resistance were observed.
The potential retinal blue hazard from dental examination lamps at different ages
Authors: Alzahrani Hind Saeed 
Published: March 2024

Abstract

Background Dental examination lamps (DELs) enhance visual acuity and focus during surgical procedures and clinical exams in dental clinics. Prolonged exposure to high-intensity light can cause thermal burns and toxicities in eyes. This study examined the risk of damage to the eyes from blue radiation emitted by DELs, considering lens spectral transmission at different ages.
Methods The spectrum irradiance of 14 types of DELs manufactured by 14 companies was measured using a Hopoocolour OHSP350S spectrometer. The blue weighted radiances (LB) were computed for direct viewing at 30 cm and indirect viewing at distances of 30 cm, 50 cm, and 100 cm. The maximum daily exposure duration (tmax) was computed only for the direct viewing of light across different ages (1–70 years old).
Results LED-based DELs have peak blue spectral radiances of between 440 and 450 nm. Indirectly viewing any of the tested DELs is safe. DEL characteristics and human eye light transmission at different ages determined the direct viewing LB values as ranging from 3 to 483 W.m-2.sr-1. Luna, with the lowest blue light radiance of 0.09 ± 0.05, has the longest tmax value. The shortest tmax value was obtained with SKEMA 6, which had the highest mean blue light radiance of 4.75 ± 3.41.
Conclusion Retinal tissue damage from cumulative direct light viewing decreases from 1 to 70 years of age. This decrease in retinal tissue damage rises with blue light radiance. The maximum acceptable ocular exposure limits for DELs and ages were computed to inform decisions on avoiding blue light.
Optico-chiasmatic distortions in pituitary adenomas: correlation between postoperative morphological reversal and follow-up functional visual recovery
Authors: Sarkar Sauradeep , Thakar Sumit , Sunil Akhil , Alle Prashanth , Aryan Saritha , Hegde Alangar S 
Published: March 2024

Abstract

Purpose:
To objectively correlate distortions of optic apparatus morphology in patients with visual outcomes in patients with pituitary adenomas undergoing transsphenoidal surgery.
Methods:
In this retrospective analysis, visual acuity (VA), visual field (VF) and total visual (TV) function was objectively scored in patients selected from an institutional cohort of pituitary adenomas. The following imaging measures of optico-chiasmatic morphology were recorded preoperatively, and at 3 months after surgery: chiasm area (CA), mid-chiasm height (CH), optic nerve-canal bending angle (BA), and optic nerve kinking angle (ONKA).
Results:
Seventy-one eyes were individually studied. VA, VF and TV scores significantly improved after surgery, both at the 3-month and at the 1-year follow-up visits (p<0.001). Craniocaudal tumor dimension was significantly associated with VA, VF and TV scores, both pre- and post-operatively. There were significant changes in CH (p<0.001), BA (p<0.001) and ONKA (p<0.001) at 3 months after surgery, but not in CA (p=0.061). Baseline VA, VF and TVS scores were positively correlated with preoperative CH and ONKA, while VF and TV scores also demonstrated significant negative correlations with preoperative BA. VF scores at 1-year follow-up were significantly correlated with preoperative and change in BA values, as well as with preoperative and change in ONKA values. Chiasm sag was noted in 45.8% of patients at one year follow-up, but was not associated with delayed visual deterioration in any case.
Conclusions:
Anatomic realignment of the optic apparatus at 3 months following transsphenoidal surgery month predicts VF scores at 1 year follow-up, but not VA or TV scores.
Stress Intensity Factor and T-stress in Lip-shaped Cracks in finite and infinite plates
Authors: Moradi Meysam , Hosseini Seyed Reza , Yaghobifar Mohammad , Aghdam Milad Zolfipour 
Published: March 2024

Abstract
Lip-shaped holes are conventionally seen in industrial sheet structures. Due to the notch-type cusp in these holes, the stress intensity around the cusp is the main reason for failure. Hence, the stress intensity factor investigation is crucially important in these holes. The current study focuses on the stress intensity factor around lip-shaped holes in finite and infinite sheets using numerical and experimental methods. In the first step, the stress intensities around a lip-shaped hole with various geometry in infinite sheets were numerically determined by the ANSYS software. Then, focusing on the finite sheet, the effect of sheet size and hole geometry on the stress intensity factor were investigated in finite sheets. Results were in great agreement with the analytical solutions proposed in the literature. In this section, the T-stress parameter was also determined in all cases. The T-stress in most cases considerable, meaning that this parameter must be taken into account in industrial design and assessments. In the second step, the digital image correlation technique was employed for validation. Three specimens with various hole geometries were tested, and the validation was successfully done.
Histomorphometric and Ultrastructural Study of Gestational Changes in Mouse Liver Using Haematoxylin and Eosin, Periodic acid Schiff stain
Authors: Mohammed Amenah Salman 
Published: March 2024

Abstract

Background: Studying the makeup of a mouses liver, such, as its lobes, lobules and how hepatocytes are organized is important, for researching changes that occur during pregnancy.
Aim of Study: the purpose of this study is to assess the structural, morphological, and general histological differences in liver tissue during pregnancy, including weight changes in the liver and total body weight, morphometric analysis and statistical assessment of hepatocytes, and glycogen concentration in the liver.
Methodology: The study involved a comparative investigation between pregnant and non-pregnant mice on liver weight, total body weight, hepatocyte size, and glycogen concentration with utilized hematoxylin, eosin, and Periodic Acid Schiff stain for histological examination and applied statistical tools for data analysis.
Results: Pregnant mice showed a significant increase (p=0.0001), in both liver and overall body weight and examination of the cell measurements indicated that the liver cells, in mice were larger indicating alterations. Glycogen concentration significantly increased in the livers of pregnant mice (p=0.0001), indicating altered metabolic demands.
Conclusion: Pregnancy induces noticeable changes in liver weight, hepatocyte size, and glycogen storage, reflecting the liver's adaptive response to the increased metabolic needs during gestation.
Hom-pre-Poisson superalgebras and Dual Hom-pre-Poisson superalgebras
Authors: Aloulou Walid 
Published: March 2024

Abstract
In this research paper, we investigate the concept of Hom-superalgebras obtained by an internal law defined on ℤ2-graded vector space A equipped with an algebra morphism f.
Given a structure of Hom-pre-Lie superalgebra (A,◊,f) and Hom-Zinbiel superalgebras (A,Λ,f), we define the structure of Hom-pre-Poisson superalgebras (A,◊,Λ,f) verifying two compatibility conditions between ”◊” and ”Λ”. On the one hand, we demonstrate that when A is a Hom-pre-Lie superalgebra, then a tensoriel algebra of A has a structure of Hom-pre-Poisson superalgebra. On the other hand, we prove that any Hom-Poisson superalgebra equipped with a Baxter operator can define a structure of Hom-pre-Poisson superalgebra. Furthermore, we combine a structure of Hompermutative superalgebra and Hom-Leibniz superalgebra on the same space, we define a structure of dual Hom-pre-Poisson superalgebra and we reveal that any Hom-Poisson superalgebra equipped with an Averaging operator can define a structure of dual Hom-pre-Poisson superalgebra.
(MSC) : 17A60, 17A30, 17D30, 17B63, 17A36.
The implication of spatiotemporal rainfall distribution on the estimation of areal rainfall characteristics in Upper Erer Sub-basin, Ethiopia
Authors: Abrahim Mummed Bedasa , Seleshi Yilma 
Published: March 2024

Abstract

The distribution of rainfall is not uniform in various regions of the world. Rainfall study is used to recognize the characteristics, duration, and variability of temporal and spatial rainfall distributions. In Ethiopia, the annual and seasonal rainfall distributions are variable in space and time. This study is focused on the implication of spatiotemporal rainfall distribution on the areal rainfall characteristics evaluation under the Upper Erer Sub-basin, located in Eastern Ethiopia. In the study area, average annual rainfall amount for Dire Dawa, Harar and Haramaya, Girawa, and Gursum stations are found to be 647, 816, 801, 958, and 840 mm with coefficients of variation of 23, 20, 20, 19, and 31%, respectively. However, the rain gauges here are sparsely distributed. The rainfall occurrence and distribution at various gauging stations have been found to vary significantly both temporally and spatially. The rainfall occurrence and distribution at various gauging stations had been found to vary significantly both temporally and spatially. The spatiotemporal rainfall distribution found in the stations was assessed using a joint probability of rain days approach. The result indicated joint probability of rain days estimation approach under monthly time step has better performance than daily, decadal, and seasonal data. The joint probability approach is used along with rainfall amount under monthly rainfall for areal rainfall estimation assessment in rainfall–runoff modeling.
MANUAIS DE NORMALIZAÇÃO PARA TRABALHOS ACADÊMICOS
Authors: Francisco de Lima Antonia Lucineide , Brasil Marcus Vinicius de Oliveira 
Published: March 2024

Introdução: A publicização de dados acadêmicos e científicos tem sido considerável nos últimos anos, de modo que quem tem acesso pode analisar e refletir sobre a forma como são divulgados, incluindo os conhecimentos técnicos, em especial na área da normalização. Em contraponto, há imprecisão nos instrumentos organizacionais, a exemplo da elaboração e publicação de manuais institucionais que levam a reflexão de como algumas orientações disseminam esse processo conduzindo a erros. Objetivo: Analisar a precisão do conteúdo dos manuais de normalização de instituições de ensino superior na cidade de João Pessoa/PB em conformidade com as normas da ABNT para trabalhos acadêmicos. Metodologia: Metodologicamente se caracteriza como uma pesquisa exploratória e descritiva de cunho bibliográfico, documental, com análise qualitativa. Resultados: Os resultados trazem como evidência problemas de imprecisão nos documentos organizacionais aos quais se teve acesso. Os erros percebidos dizem respeito a instruções básicas, trazendo sugestões gerais dos organismos normalizadores mais amplos. Conclusão: conclui-se que existe imprecisão nos documentos organizacionais analisados, cujos equívocos dizem respeito às instruções básicas, desde a elaboração da capa para trabalhos acadêmicos, até aspectos normativos trazendo sugestões gerais dos organismos normalizadores mais amplos. Essas informações equivocadas, além de trazerem prejuízos aos pesquisadores e alunos, pode-se induzir ao erro, até mesmo a usuários mais especializados.