bluuebunny/crossref_metadata_2025_split huggingface dataset:
Contemporaneity of the Tree of Life Image in the Towels of Poltava Region of the 19th and 20th Centuries
Authors: Gamaliia Kateryna , Bezuhla Anastasiia 
Published: April 2024

The purpose of the article consists in identifying and analysing the ornaments of traditional towel embroidery of the Poltava region of the nineteenth and twentieth centuries, the peculiarities of the technique and technology of their production with a focus on the Tree of Life motif for the full reproduction of its authentic meaning in contemporary design.
Research methodology is based on the methods of comparison, analysis and analogies used for a detailed literature analysis. Induction and deduction methods were useful for identifying the characteristic manifestations of the Poltava tradition against the background of embroidered towels of Ukraine. The typological and comparative methods were used in the study of the Poltava region territorial features. The historical method made it possible to study and identify the sequence of embroidery formation, symbolic and semantic features in embroidered towels. The scientific novelty of the article lies in the comparison of the principles of depicting the Tree of Life in embroidered towels of Podillia, Polissia, and Poltava region of the nineteenth and twentieth centuries; in the formation of a semiotic meanings list of the Tree of Life in towels of Poltava region, which have been scattered in various scientific works. The article provides recommendations for compliance with the authentic content in the interpretation of the symbolic elements of the Tree of Life image in the products of modern designer clothing brands. Conclusions. The Tree of Life is a complex ornamental element of embroidery, especially evident in the Poltava region, and has a wide range of symbolic meanings: a cosmogonic model of the world, the trinity of the three worlds, Family Tree, Mother Guardian, Holy Trinity, and Our Lady Oranta. In the Poltava region, the image of the Tree of Life in towels has been a well-established tradition since the nineteenth and twentieth centuries, with characteristic details in the form of fancy flowers. One of the reasons for the levelling of the sacred and magical load of the Tree-Flower in the ornamental compositions of modern clothing brands can be considered a tendency to generally lighten the informational and philosophical content of the product following consumer tastes. Some Ukrainian designers and brands demonstrate options for models of a successful combination of folklore motifs and authentic tradition with modern fashion trends. Individual Ukrainian designers and brands demonstrate variants of models that successfully combine folklore motifs and authentic tradition with modern fashion trends. Brands recreate traditional embroidery in their own interpretation, so the variety of techniques and technologies for demonstrating embroidery has a rich potential for development.
A Modest Contribution to the Riemann Hypothesis Using the Poincaré Index
Authors: Oliveira Hime 
Published: April 2024

This work uses a new approach to investigate the Riemann hypothesis, drawing conclusions about its trueness. It is based on the more general method presented in a very recent publication, by the same author, showing in detail how to approach that very well-known and interesting problem. This is achieved by means of the theory of dynamical systems (Poincaré index associated to equilibria of 2-dimensional systems) and the study of the zeros of the Dirichlet eta function, defined by a Dirichlet series. By using the well-known fact that the zeros of the eta function would include all zeros of the Riemann zeta function in the (open) critical strip, excluded the critical line, \(( (0,1/2) \cup (1/2, 1) ) \times (-\infty , \infty)\), the development proceeds using only the eta function. In addition, the open and simply connected region \((1/2 , 1) \times (0 , \infty)\) is used along the text, taking into account the symmetries of zeros of the functions under analysis in the critical strip. The basic line of proof is to find the mathematical expression for the Poincaré index of the vector field associated to the eta function, assuming the existence of a zero of the eta function outside the critical line (in \((1/2 , 1) \times (0 , \infty)\)), and investigating the resulting unfoldings. Eventually, an inconsistency occurs and the proof ends by contradiction.
Road Accident Prediction Using Machine Learning
Authors: Dr. M. Hemalatha  , S. Dhuwaraganath  
Published: April 2024

Road accidents are a significant cause of fatalities and injuries worldwide. Predicting road accidents is crucial for implementing preventive measures and saving lives. This paper presents a deep learning-based road accident prediction system utilizing various factors such as speed, traffic condition, weather, and more. By leveraging publicly available datasets and external data sources, the model aims to accurately predict road accidents, ultimately contributing to enhancing road safety.
Presentasi Visual dalam Tata Kemas Sego Pincuk Terhadap Persepsi Gastronomi dan Kenikmatan
Authors: Sutrisno Andika Agung 
Published: April 2024

Konsumsi makanan telah berkembang dari kebutuhan dasar manusia menjadi pilihan gaya hidup. Eksplorasi peran kemasan dalam membentuk persepsi konsumen terhadap preferensi selera, dengan fokus pada makanan siap saji dalam wadah daun pisang dikenal sebagai "pincuk". Sego Pincuk menarik perhatian tidak hanya karena cita rasa khasnya, tetapi juga karena presentasi visual yang sederhana. Penggunaan daun pisang sebagai kemasan alami mencerminkan kearifan lokal dalam memanfaatkan sumber daya secara berkelanjutan dan meningkatkan pengalaman gastronomi dengan sensasi alami. Gastronomi tidak hanya mencakup rasa dan tekstur makanan, tetapi juga menjelajahi sejarah, tradisi, dan nilai-nilai yang terkait dengan konsumsi makanan di dalam kebudayaan. Presentasi visual Sego Pincuk berperan penting dalam pembentuk persepsi awal konsumen terhadap hidangan yang akan dipilih pembeli. Penelitian menggunakan pendekatan deskriptif kualitatif untuk memahami dampak presentasi visual terhadap gastronomi dan pengalaman estetis akibat persepsi visual. Observasi langsung, wawancara, dan analisis konten dilakukan dalam mengupas fenomena sego pincuk untuk mendapatkan wawasan holistik tentang bagaimana presentasi kemasan secara visual mempengaruhi respons dan preferensi konsumen. Presentasi visual kemasan tradisional berperan sebagai penghubung emosional konsumen dengan warisan budaya dan preferensi kuliner. Ikatan emosional menjadi penting untuk mempertahankan dan mempromosikan nilai-nilai budaya tradisional dalam pengalaman kuliner yang kaya dengan cita rasa dan estetika otentik.
Tiedejulkaisemisesta syrjinnästä vapaa alue
Authors: Isopahkala-Bouret Ulpukka 
Published: April 2024

Yhdenvertaisuuden periaate koskee tiedejulkaisemista siinä missä muutakin tutkimustoimintaa. Se edellyttää taustoihin tai ominaisuuksiin perustuvan syrjinnän kieltämistä ja tieteentekijöiden tasavertaisia mahdollisuuksia julkaista tutkimustaan. Periaate kuulostaa itsestään selvältä, mutta piiloista syrjintää on pesiytynyt myös tiedejulkaisemisen käytäntöihin. Tiedejulkaisemisen moninaisuuden, yhdenvertaisuuden ja inklusiivisuuden edistäminen puhuttavat myös kansainvälisesti, ja kustantamot ovat tarttuneet toimiin,
Undergraduate Students’ Perception on Using Ome tv as a Tool in Improving English Speaking Skill
Authors: Jalil Hasibul , Islam Muhammad Hifdil , Hamdany Beny 
Published: April 2024

One of the obstacles to learning English as a foreign language, especially speaking skills, is the lack of practice outside the classroom. In this globalization era, there are a lot of media options available that can be used as learning tools, such as Ome TV, a social media platform that can be used as a useful alternative for practicing English-speaking skills outside the classroom. This research aims to find students' perceptions of the use of Ome TV to improve their English-speaking skills. This research uses a qualitative-descriptive method. This research uses interviews to collect data. The participants in this research were six students from the English education department. The results of this research reveal that Ome TV provides English learners the opportunity to practice speaking English with foreigners from various countries via video chat. Using Ome TV is very effective for improving English speaking skills, which include fluency, pronunciation, expanding vocabulary, and improving English communication skills. Ome TV is effective for English-speaking skills, but it is not effective for aspects of English accuracy because Ome TV is a random video chat.
Effects of aging on the biomechanical properties of the lung extracellular matrix: dependence on tissular stretch
Authors: Ulldemolins Anna , Narciso Maria , Sanz-Fraile Héctor , Otero Jorge , Farré Ramon , Gavara Núria , Almendros Isaac 
Published: April 2024

Introduction: Aging induces functional and structural changes in the lung, characterized by a decline in elasticity and diminished pulmonary remodeling and regenerative capacity. Emerging evidence suggests that most biomechanical alterations in the lung result from changes in the composition of the lung extracellular matrix (ECM), potentially modulating the behavior of pulmonary cells and increasing the susceptibility to chronic lung diseases. Therefore, it is crucial to investigate the mechanical properties of the aged lung. This study aims to assess the mechanical alterations in the lung ECM due to aging at both residual (RV) and functional (FV) lung volumes and to evaluate their effects on the survival and proliferation of mesenchymal stromal cells (MSCs).Methods: The lungs from young (4-6-month-old) and aged (20-24-month-old) mice were inflated with optimal cutting temperature compound to reach FV or non-inflated (RV). ECM proteins laminin, collagen I and fibronectin were quantified by immunofluorescence and the mechanical properties of the decellularized lung sections were assessed using atomic force microscopy. To investigate whether changes in ECM composition by aging and/or mechanical properties at RV and FV volumes affects MSCs, their viability and proliferation were evaluated after 72 h.Results: Laminin presence was significantly reduced in aged mice compared to young mice, while fibronectin and collagen I were significantly increased in aged mice. In RV conditions, the acellular lungs from aged mice were significantly softer than from young mice. By contrast, in FV conditions, the aged lung ECM becomes stiffer than that of in young mice, revealing that strain hardening significantly depends on aging. Results after MSCs recellularization showed similar viability and proliferation rate in all conditions.Discussion: This data strongly suggests that biomechanical measurements, especially in aging models, should be carried out in physiomimetic conditions rather than following the conventional non-inflated lung (RV) approach. The use of decellularized lung scaffolds from aged and/or other lung disease murine/human models at physiomimetic conditions will help to better understand the potential role of mechanotransduction on the susceptibility and progression of chronic lung diseases, lung regeneration and cancer.
Effect of anticoagulation on the incidence of venous thromboembolism, major bleeding, and mortality among hospitalized COVID-19 patients: an updated meta-analysis
Authors: Chen Xinwang , Zhang Suyun , Liu Haiyu , Zhang Qianyuan , Chen Jinghan , Zheng Qixian , Guo Ningjing , Cai Yuanyuan , Luo Qiong , Xu Qian , Yang Sheng , Chen Xiangqi 
Published: April 2024

ObjectiveAnticoagulation is crucial for patients hospitalized with coronavirus disease 2019 (COVID-19) due to the high risk of venous thromboembolism (VTE). However, the optimal anticoagulation regimen needs further exploration. Therefore, we evaluated the efficacy and safety of diverse anticoagulation dosage dosages for COVID-19.MethodsAn updated meta-analysis was performed to assess the effect of thromboprophylaxis (standard, intermediate, and therapeutic dose) on the incidence of VTE, mortality and major bleeding among COVID-19 patients. Literature was searched via PubMed, EMBASE, Web of Science, and China National Knowledge Infrastructure (CNKI) database. The odds ratio (OR) and 95% confidence interval (CI) were calculated for effect estimates.ResultsNineteen studies involving 25,289 participants without VTE history were included. The mean age of patients was 59.3 years old. About 50.96% were admitted to the intensive care unit. In the pooled analysis, both therapeutic-dose and intermediate-dose anticoagulation did not have a significant advantage in reducing VTE risk over standard dosage (OR = 1.09, 95% CI: 0.58–2.02, and OR = 0.89, 95% CI: 0.70–1.12, respectively). Similarly, all-cause mortality was not further decreased in either therapeutic-dose group (OR = 1.12, 95% CI: 0.75–1.67) or intermediate-dose group (OR = 1.34, 95% CI: 0.83–2.17). While the major bleeding risk was significantly elevated in the therapeutic-dose group (OR = 2.59, 95%CI: 1.87–3.57) as compared with the standard-dose regimen. Compared with intermediate dosage, therapeutic anticoagulation did not reduce consequent VTE risk (OR = 0.85, 95% CI: 0.52–1.38) and all-cause mortality (OR = 0.84, 95% CI: 0.60–1.17), but significantly increased major bleeding rate (OR = 2.42, 95% CI: 1.58–3.70). In subgroup analysis of patients older than 65 years, therapeutic anticoagulation significantly lowered the incidence of VTE in comparation comparison with standard thromboprophylaxis, however, at the cost of elevated risk of major bleeding.ConclusionOur results indicated that for most hospitalized patients with COVID-19, standard-dose prophylactic anticoagulation might be the optimal choice. For elderly patients at low risk of bleeding, therapeutic-dose anticoagulation could further reduce VTE risk and should be considered especially when there were other strong risk factors of VTE during hospital stay.Systematic Review Registrationhttps://www.crd.york.ac.uk/PROSPERO, identifier, CRD42023388429.
Minor straw return enhances net income in a maize-wheat rotation system
Authors: Li Juan , Guo Zhen , Ye Shenglan 
Published: April 2024

Straw returning to the field is a common agricultural practice in China. Nevertheless, in the maize-wheat rotation system of the semi-arid region in Northwest China, it is essential to investigate the optimal approach for coupling straw return and fertilization in order to enhance soil quality and crop yield. A field trial conducted in the semi-arid region of northwest China from 2019 to 2021 examined eight different combinations of straw return and fertilization rates. The results indicated that while straw return had minimal impact on soil total nitrogen in the 0–60 cm layer, it did increase soil available phosphorus and potassium in the 0–40 cm layer. Additionally, all straw return treatments notably improved soil organic matter and humus content compared to the untreated control (CK). Specifically, applying N and P fertilizers in combination with returning 1/3 of the straw (NP+1/3S) produced in that season significantly boosted soil organic matter and humus content compared to the CK. Moreover, the NP+1/3S treatment led to a substantial enhancement in the grain yield of wheat and maize, as well as their yield components, including an increase in the number of ears/spikes per square meter, the number of grains per ear/spike, and the 100 or 1000-grain weight. The results may be attributed to a combination of factors, including improved nutrient availability, enhanced soil structure, and increased microbial activity due to the incorporation of straw. Economic analysis showed that NP+1/3S had the highest production to investment ratio (ROI), indicating its potential suitability for the region. This study highlights the significance of carefully selecting combinations of straw return and fertilization to maximize soil fertility, crop yield, and economic benefits in agricultural systems.
TMBcalc: a computational pipeline for identifying pan-cancer Tumor Mutational Burden gene signatures
Authors: Privitera Grete Francesca , Alaimo Salvatore , Caruso Anna , Ferro Alfredo , Forte Stefano , Pulvirenti Alfredo 
Published: April 2024

Background:In the precision medicine era, identifying predictive factors to select patients most likely to benefit from treatment with immunological agents is a crucial and open challenge in oncology.Methods:This paper presents a pan-cancer analysis of Tumor Mutational Burden (TMB). We developed a novel computational pipeline, TMBcalc, to calculate the TMB. Our methodology can identify small and reliable gene signatures to estimate TMB from custom targeted-sequencing panels. For this purpose, our pipeline has been trained on top of 17 cancer types data obtained from TCGA.Results:Our results show that TMB, computed through the identified signature, strongly correlates with TMB obtained from whole-exome sequencing (WES).Conclusion:We have rigorously analyzed the effectiveness of our methodology on top of several independent datasets. In particular we conducted a comprehensive testing on: (i) 126 samples sourced from the TCGA database; few independent whole-exome sequencing (WES) datasets linked to colon, breast, and liver cancers, all acquired from the EGA and the ICGC Data Portal. This rigorous evaluation clearly highlights the robustness and practicality of our approach, positioning it as a promising avenue for driving substantial progress within the realm of clinical practice.
Exploring barriers and educational needs in implementing dual-task training for Parkinson’s disease: insights from professionals
Authors: Domingos Josefa , Dean John , Fernandes Júlio Belo , Família Carlos , Fernandes Sónia , Godinho Catarina 
Published: April 2024

IntroductionThere is growing evidence suggesting that dual-task training benefits people with Parkinson’s disease (PD) on both physical and cognitive outcomes. However, there is no known data regarding professionals’ educational needs and barriers to its implementation. This study aimed to explore the barriers and educational needs of healthcare and exercise professionals to integrate dual-task training into their practice with people with PD.MethodsWe conducted a study based on a web survey. Social media channels were used to recruit a convenience sample of exercise and healthcare professionals working with people with PD.ResultsOf the 185 eligible responses, the majority were physiotherapists (68.1%) followed by occupational therapists (10.8%). Most participants attended Parkinson specific training (88.6%) and employed the treatments set up in individual one on-one sessions (58.9%). We identified several barriers to dual-task training implementation, with lack of time (to prepare materials), staying creative and/ or accessing new ideas, unreliable tools for measuring gains, and insufficient expertise as the most referred by participants. The educational needs most referred included accessing examples of interventions in general, knowing what strategies to apply and their application for people with different symptoms.DiscussionOur results highlight that professionals remain challenged to integrate dualtask training into PD clinical care mainly due to knowledge gaps, difficulties in accessing new ideas, and lack of time.
Effects of vaginal progesterone and placebo on preterm birth and antenatal outcomes in women with singleton pregnancies and short cervix on ultrasound: a meta-analysis
Authors: Peng Limin , Gao Yan , Yuan Chengkun , Kuang Hongying 
Published: April 2024

BackgroundVaginal progesterone in preterm birth and adverse outcomes caused by cervical insufficiency remains controversial. To address it, the effect of vaginal progesterone on preterm delivery and perinatal outcome of single pregnancy women with short cervix (less than 25 mm) was systematically evaluated by meta-analysis.Methods“Vaginal progesterone,” “placebo,” “ultrasound,” “cervix,” “singleton pregnancy,” “preterm birth,” and “antenatal outcomes” were entered to screen clinical studies PubMed, Embase, and the Chinese Biomedical Literature Database (CBM). The study population consisted of women with singleton pregnancies and a short cervix on ultrasound, and were assigned into the progesterone group (n = 1,368) and the placebo group (n = 1,373). Treatment began after the patient was diagnosed with short cervix until delivery. Neonatal survival rate, Neonatal Intensive Care Unit (NICU) admission rate, respiratory distress syndrome (RDS), intraventricular hemorrhage (IVH), neonatal mortality, and birth weight &lt;1,500 g were analyzed.ResultsA total of 8 articles, totaling 2,741 study subjects, were enrolled. The progesterone group exhibited an obvious reduced rate of preterm birth at &lt;34 weeks (OR = 0.67, 95% CI: 0.53∼0.84; Z = 3.53, P = 0.004), preterm birth at &lt;32 weeks (OR = 0.46, 95% CI: 0.28∼0.77; Z = 2.99, P = 0.003), NICU admission rate (OR = 0.45, 95% CI: 0.30∼0.66; Z = 0.15, P &lt; 0.0001), RDS rate (OR = 0.42, 95% CI: 0.28∼0.63; Z = 4.25, P &lt; 0.0001), IVH incidence rate (OR = 0.40, 95% CI: 0.17∼0.95; Z = 2.08, P = 0.04), neonatal mortality (OR = 0.25, 95% CI: 0.13∼0.46; Z = 4.39, P &lt; 0.0001), and proportion of neonates with birth weight &lt; 1,500 g (OR = 0.45, 95% CI: 0.32∼0.64; Z = 4.50, P &lt; 0.0001).ConclusionVaginal progesterone lowered the incidences of preterm birth and adverse pregnancy outcomes in women with singleton pregnancies and a short cervix.
Membrane stripping in group B streptococcus carriers does not impede adequate intrapartum antibiotic prophylaxis: a retrospective study
Authors: Kabiri Doron , Paltiel Ora , Ofek-shlomai Noa , Nir-Paz Ran , Sompolinsky Yishai , Ezra Yossef 
Published: April 2024

ObjectiveMembrane stripping in group B streptococcus (GBS) carriers poses an increased risk of inadequate antibiotic prophylaxis, potentially due to accelerated labor, thereby potentially impacting the management of GBS colonization during delivery. We compared the adequacy of intrapartum antibiotic prophylaxis between pregnant women colonized with GBS, who underwent membrane stripping and those who did not. The study aimed to determine whether the performance of membrane stripping, by potentially shortening labor duration, increases the risk of inadequate antibiotic prophylaxis dispensation.Study designA retrospective cohort study was conducted on GBS screen-positive women with a full-term singleton pregnancy in cephalic presentation, who were eligible for vaginal delivery. The exposed group consisted of women who underwent membrane stripping, while the unexposed group consisted of women who did not undergo membrane stripping. The primary outcome was defined as inadequate duration of antibiotic prophylaxis during labor, wherein less than 4 h of beta-lactam antibiotics were administered prior to delivery. Neonatal outcome was compared between the groups.ResultsThis retrospective cohort study comprised 1,609 women, with 129 in the exposed group (stripping group) and 1,480 in the unexposed group (no stripping group). Adequate intrapartum antibiotic prophylaxis was received by 64.3% (83/129) of the exposed group, compared to 46.9% (694/1,480) of the unexposed group (p = 0.003). Membrane stripping was associated with increased odds of receiving adequate prophylaxis (OR 1.897, 95% CI 1.185–3.037, p = 0.008). After excluding women who presented to the labor ward in active labor and delivered in less than 4 h, both the exposed and unexposed groups had similarly high rates of adequate intrapartum antibiotic prophylaxis (87.5% vs. 85.8%, respectively). No significant difference was observed in adverse neonatal outcomes between the groups.ConclusionThe provision of membrane stripping did not impede adequate intrapartum antibiotic prophylaxis and was correlated with a higher rate of sufficient prophylaxis in comparison to non-swept patients. These observations suggest that membrane stripping can be considered a safe option for ensuring adequate antibiotic prophylaxis in women colonized with GBS.