bluuebunny/crossref_metadata_2025_split huggingface dataset:
Drought and vegetation restoration lead to shifts in soil microbial diversity and co-occurrence networks in California coastal prairie
Authors: Yang Xuechen , Loik Michael E. , Wu Xuefeng , Luong Justin C. , Wei Xiaowei , Li Lu-Jun 
Published: March 2024

Abstract
Background and aims
Both drought and vegetation restoration can have dramatic effects on plant community composition, but how they influence soil microbial community diversity, structure, and co-occurrence networks remain less well known.

Methods
To better understand the regulatory mechanisms of drought and vegetation restoration on soil microorganisms, we planted 12 native species in precipitation manipulation experimental plots in an invaded coastal grassland in California, USA. We measured soil bacterial and fungal community composition by amplicon sequencing, and quantified plant species richness and coverage in the third experimental year.

Results
Our results showed that drought significantly altered soil bacterial diversity and composition; however, neither drought nor vegetation restoration had significant effects on fungal diversity and composition. The control plots had the most cooperative interactions (greatest number of correlations) among bacterial and/or fungal species, while drought plots yielded the most complex co-occurrence network with the highest modularity and clustering coefficient. Structural equation modeling revealed that plant species richness, net gains, and soil moisture played dominant roles in shaping bacterial community structure. Drought and bacterial community structure directly affected fungal community structure. Plant dominant species cover, common species cover, and bacterial diversity were the key drivers in regulating the microbial co-occurrence network complex.

Conclusion
We conclude that soil bacterial and fungal communities differ in their responses to abiotic and biotic environmental changes, which may weaken the interspecies interactions among soil microorganisms.
Learning to ride the high growth “Rollercoaster”: the role of publicly funded business accelerator programmes
Authors: Brown Ross , Rees-Jones Rachael 
Published: March 2024

Abstract
High growth firms (HGFs) are a vital determinant of regional economic competitiveness. This paper examines the effectiveness of a Welsh publicly funded business accelerator programme (BAP) designed to nurture HGFs via relational support measures. The paper teases out both the support requirements sought by high growth entrepreneurs, together with the perceived effectiveness of the programme’s offering. Hitherto, the literature has been silent in terms of the mental well-being and psychological resilience of founders of HGFs. This study discovered how mental well-being and psychological resilience of entrepreneurs was very acutely and detrimentally affected when experiencing periods of rapid firm growth. The research also uncovered a disconnect between the support needs of HGFs and those provided by BAPs. To help develop the capabilities and durability of entrepreneurs, “growth readiness” coaching together with psychological resilience training seem appropriate policy measures to help entrepreneurs successfully navigate turbulent episodes of high growth.
Sexuality of People with Intellectual Disabilities: Dynamic with Parents and Social Services Personnel in a Chinese Context
Authors: Lam Angus Y. K. , Yau Matthew K. S. , Franklin Richard C. , Leggat Peter A. 
Published: March 2024

AbstractSexuality is a valuable part of people’s lives, including people with intellectual disabilities (ID). Parents and social services personnel are significant parties for promoting the autonomy of people with ID regarding sexuality, although evidence reveals their actions tend to be in the opposite direction. Sexual attitudes do not emerge solely as personal or individual but evolve from interactions with others in a particular sociocultural environment. To explore the sexuality of people with ID, this study set out to understand the dynamic of people with ID, parents and social services personnel within the cultural context of Hong Kong. In total, 19 participants including people with mild ID, parents and social services personnel were recruited. Individual interviews were conducted, and the data were analyzed applying Interpretative Phenomenological Analysis and dramaturgy. Findings revealed the participants’ experiences, obstacles, and underlying feelings regarding the sexuality of people with ID, and the phenomenon, “not taking action” formed by all the groups. Chinese Confucian culture was revealed as the factor influencing the dynamic on the issues of sexuality. With respect to cultural expectations, government and social services agency leadership should take the lead to adopt an evidence-based sex education protocol.
Comparative analysis of CAMS aerosol optical depth data and AERONET observations in the Eastern Mediterranean over 19 years
Authors: Tuna Tuygun Gizem , Elbir Tolga 
Published: March 2024

AbstractAerosol optical depth (AOD) is an essential metric for evaluating the atmospheric aerosol load and its impacts on climate, air quality, and public health. In this study, the AOD data from the Copernicus Atmosphere Monitoring Service (CAMS) were validated against ground-based measurements from the Aerosol Robotic Network (AERONET) throughout the Eastern Mediterranean, a region characterized by diverse aerosol types and sources. A comparative analysis was performed on 3-hourly CAMS AOD values at 550 nm against observations from 20 AERONET stations across Cyprus, Greece, Israel, Egypt, and Turkey from 2003 to 2021. The CAMS AOD data exhibited a good overall agreement with AERONET AOD data, demonstrated by a Pearson correlation coefficient of 0.77, a mean absolute error (MAE) of 0.08, and a root mean square error (RMSE) of 0.11. Nonetheless, spatial and temporal variations were observed in the CAMS AOD data performance, with site-specific correlation coefficients ranging from 0.57 to 0.85, the lowest correlations occurring in Egypt and the highest in Greece. An underestimation of CAMS AOD was noted at inland sites with high AOD levels, while a better agreement was observed at coastal sites with lower AOD levels. The diurnal variation analysis indicated improved CAMS reanalysis performance during the afternoon and evening hours. Seasonally, CAMS reanalysis showed better agreement with AERONET AODs in spring and autumn, with lower correlation coefficients noted in summer and winter. This study marks the first comprehensive validation of CAMS AOD performance in the Eastern Mediterranean, offering significant enhancements for regional air quality and climate modeling, and underscores the essential role of consistent validation in refining aerosol estimations within this complex and dynamic geographic setting.
Water’s path from moss to soil Vol. 2: how soil-moss combinations affect soil water fluxes and soil loss in a temperate forest
Authors: Gall Corinna , Nebel Martin , Scholten Thomas , Thielen Sonja M. , Seitz Steffen 
Published: March 2024

AbstractMosses are key components of many ecosystems and particularly related to water cycling. In principle, the importance of mosses for water-related processes is known; however, their influence is rarely quantified in scientific studies. To fill this research gap, this study concentrates on the influence of mosses of different species on surface runoff, the amount of percolated water, soil loss, and the temporal dynamics of soil water content. For this purpose, an experimental approach consisting of an ex situ rainfall simulation (45 mm h− 1 for 30 min) with infiltration boxes equipped with biocrust wetness probes was applied. On average, mosses significantly reduced surface runoff by 91% and soil loss by almost 100%, while the amount of percolated water was increased by 85% compared with bare soils. These processes were superimposed by desiccation cracks, and partly water repellency, with the result that the respective influences could not be quantified individually. However, by simultaneously measuring the water content in the substrates during rainfall simulations, we were able to achieve a better understanding of the water flows in the substrates. For instance, water content at 3 cm substrate depth was higher under mosses than in bare soils, implying that mosses facilitated infiltration. In this study, we were able to demonstrate that mosses play an important role in soil hydrology and in protecting the soil from erosion, and it is imperative that further experiments will be conducted to elucidate the apparently underestimated effects of mosses and their specific traits on soil water fluxes and sediment transport.
Research Progress on the Experimental Model and Underlying Mechanistic Studies of Tension-Type Headaches
Authors: Fu Guo-jing , Wang liu-ding , Chi Xian-su , Liang Xiao , Wei Jing-jing , Huang Zhi-hong , Shen Wei , Zhang Yun-ling 
Published: March 2024

Abstract
Purpose of Review
Tension-type headaches (TTH) significantly diminish patients’ quality of life and increase absenteeism, thereby imposing a substantial economic burden. Animal models are essential tools for studying disease mechanisms and drug development. However, until now, little focus has been placed on summarizing the animal models of TTH and associated mechanistic studies. This narrative review discusses the current animal models of TTH and related mechanistic studies to provide insights into the pathophysiological mechanisms of and treatments for TTH.

Recent Findings
The primary method for constructing an animal model of TTH involves injecting a solution of pain relievers, such as adenosine triphosphate, nerve growth factor, or a high concentration of salt solution, into the neck to initiate harmful cervical muscle responses. This model enables the examination of the interaction between peripheral muscles and central sensitization, which is crucial for understanding the pathophysiology of TTH. Mechanistic studies based on this model have investigated the effect of the P2X receptor antagonist, P2X7 receptor blockade, the P2Y1 receptor agonist 2-MESADP, P2Y1 receptor antagonist MRS2179, nitric oxide synthase inhibitors, and acetylsalicylic acid.

Summary
Despite notable advancements, the current model of TTH has limitations, including surgical complexity and the inability to replicate chronic tension-type headache (CTTH). To gain a more comprehensive understanding and develop more effective treatment methods, future studies should focus on simplifying surgical procedures, examining other predisposing factors, and establishing a model for chronic TTH. This will offer a deeper insight into the pathophysiological mechanism of TTH and pave the way for improved treatment approaches.
Xanthoma of the Jaw Bones: Cases Series and Review of Literature
Authors: Venkat Shankar , Islam Mohammed N. , Bhattacharyya Indraneel , Cohen Donald M. , Kratochvil F. James , Woods Tina R. , Ganatra Seema , Alramadhan Saja A. 
Published: March 2024

Abstract
Background
Intraosseous xanthomas are rare benign lesions sometimes associated with excess lipid production. Xanthoma of the jaw bones (XJB) was first reported in 1964, and fewer than 50 cases have been reported in the English literature to date. The etiopathogenesis of XJB is highly suggestive of a reactive process or a metabolic condition.

Method
Seven cases of XJBs were retrieved from the archives of 4 oral and maxillofacial pathology services. Clinical, radiographic and histopathologic features of all these cases were retrospectively analyzed. Immunohistochemical (IHC) stains for S100 and CD68 were performed.

Results
All seven cases involved the mandible. Patients’ age ranged between 13 and 69 years with an evenly distributed female to male ratio. One patient had a medical history of hyperlipidemia, but the medical and dental histories of the others were unremarkable. For most cases, XJB was an incidental finding discovered during routine radiographic examination. Swelling and cortical expansion were noted in a few cases. Radiographically, cases typically presented as either well-defined multilocular or unilocular lesions, which were either radiolucent or mixed radiolucent/radiopaque. All the lesions were treated with surgical curettage and no recurrence was observed during subsequent follow-ups. Each of the seven cases exhibited sheets of foamy macrophages. The diagnosis is established by exclusion of entities with overlapping microscopic features and involved correlation with the clinical, histological, radiographic and IHC profiles. Immunohistochemically, all the cases expressed diffuse positivity for CD68 and were negative for S100.

Conclusion
XJB is a rare lesion of unknown etiology, which may mimic other benign or reactive jaw lesions. Due to its rarity and the potential diagnostic challenges it presents, clinicians must remain vigilant and consider CXJ in their differential when assessing radiolucent jaw anomalies.
Sea level rise and extreme events along the Mediterranean coasts: the case of Venice and the awareness of local population, stakeholders and policy makers
Authors: Anzidei Marco , Alberti Tommaso , Vecchio Antonio , Loizidou Xenia , Orthodoxou Demetra , Serpelloni Enrico , Falciano Antonio , Ferrari Claudia 
Published: March 2024

AbstractSea level rise (SLR) is among the major climate change effects threating the coasts of the Mediterranean basin, which are increasingly exposed to coastal flooding, especially along the low lying coastal plains, river deltas, lagoons and reclamation areas. Coastal erosion, beach retreat and marine flooding are already causing unprecedented environmental and socio-economic impacts on coastal populations. According to the Intergovernmental Panel on Climate Change (IPCC) these effects are expected to worsen by 2100 and beyond with a projected global SLR up to about 1 m above the current level. This study provides an overview of the Mediterranean basin, focusing on the vulnerable city of Venice, which is particularly exposed to marine flooding due to SLR and land subsidence. We show the current and future sea level trend as well as a flooding scenarios in the absence of the Experimental Electromechanical Module (MoSE), which is protecting the city of Venice since 2020. To understand the awareness of citizens in Venice to address SLR, we have engaged a group of stakeholders through a structured participatory process to develop solution-oriented, case-specific and site-specific Policy Tools. Our results show that the Policy Tools contain relevant, effective and implementable actions stemming from stakeholder interaction and consensus building, identifying relevant issues that should be considered for SLR adaptation policies. A more extensive participation in public processes is required to materialize the Policy Tools into concrete actions to help vulnerable areas adapt to the expected SLR by the end of this century.
Optical solitons for dispersive concatenation model with power-law of self-phase modulation: a sub-ODE approach
Authors: Zayed Elsayed M. E. , Gepreel Khaled A. , El-Horbaty Mahmoud , El-Shater Mona , Biswas Anjan , Yildirim Yakup , Alshomrani Ali Saleh 
Published: March 2024

AbstractThis work retrieves a plethora of optical soliton solutions to the dispersive concatenation model with power-law of self-phase modulation. The implementation of the sub-ODE method and its variations and versions yielded such soliton solutions. The intermediary functions were Weierstrass’ elliptic functions as well as Jacobi’s elliptic functions. Their special cases gave way to soliton solutions. In particular, for Jacobi’s elliptic functions, when the modulus of ellipticity approached unity, the soliton solutions have naturally emerged.
Evaluation of next-generation sequencing versus next-generation flow cytometry for minimal-residual-disease detection in Chinese patients with multiple myeloma
Authors: Zhou Mo , Chen Yan , Gong Yanlei , Zhu Mingqing , Cen Jiannong , Pan Jinlan , Yan Lingzhi , Shang Jingjing , Jin Song , Shi Xiaolan , Yao Weiqin , Yan Shuang , Wu Depei , Chen Suning , Fu Chengcheng , Yao Li 
Published: March 2024

Abstract
Purpose
To evaluate the efficacy of next-generation sequencing (NGS) in minimal-residual-disease (MRD) monitoring in Chinese patients with multiple myeloma (MM).

Methods
This study analyzed 60 Chinese MM patients. During MRD monitoring in these patients’ post-therapy, clonal immunoglobulin heavy chain (IGH) rearrangements were detected via NGS using LymphoTrack assays. MRD monitoring was performed using NGS or next-generation flow cytometry (NGF), and the results were compared. Additionally, the sensitivity and reproducibility of the NGS method were assessed.

Results
The MRD detection range of the NGS method was 10–6–10–1, which suggested good linearity, with a Pearson correlation coefficient of 0.985 and a limit of detection of 10–6. Intra- and inter-assay reproducibility analyses showed that NGS exhibited 100% reproducibility with low variability in clonal cells. At diagnosis, unique clones were found in 42 patients (70.0%) with clonal IGH rearrangements, which were used as clonality markers for MRD monitoring post-therapy. Comparison of NGS and NGF for MRD monitoring showed 79.1% concordance. No samples that tested MRD-positive via NGF were found negative via NGS, indicating the higher sensitivity of NGS. MRD could be detected using NGS in 6 of 7 samples before autologous hematopoietic stem-cell transplantation, and 5 of them tested negative post-transplantation. In contrast, the NGF method could detect MRD in only 1 sample pre-transplantation.

Conclusion
Compared with NGF, NGS exhibits higher sensitivity and reproducibility in MRD detection and can be an effective strategy for MRD monitoring in Chinese MM patients.
Connecting Human and Information Resources in the Generation of Competitive Advantage
Authors: Camisón-Haba Sergio , Clemente-Almendros José Antonio , Gonzalez-Cruz Tomás 
Published: March 2024

Abstract
A key trend in recent decades is a growing standardisation of tangible digital resources. This trend coexists with development in the most advanced organisations of high-level technological, human and organisational resources teams built around advanced digital solutions. Digitisation has increased information asymmetries in organisations. However, it has changed the nature of the assets that support them. Accordingly, their effects are independent if unaccompanied by complementary investments in organisational design and human capital. This article focuses on relationships between information and cognitive asymmetries, their effects on developing strategic capabilities and their impact on competitive position. Partial least squares structural equation modelling (PLS-SEM) analysis was run on a data set of 418 Spanish tourism firms. The results show the positive effects of the interaction between human resources and information assets in strengthening the competitive position of modern organisations.
Recurrence in acromegaly: two tertiary centers experience and review of the literature
Authors: Cremaschi A. , Sala E. , Lavezzi E. , Carosi G. , Del Sindaco G. , Mangone A. , Mungari R. , Pagnano A. , Indirli R. , Ferrante E. , Mazziotti G. , Locatelli M. , Lasio G. , Arosio M. , Lania A. G. , Mantovani G. 
Published: March 2024

Abstract
Background
Recurrence of acromegaly after successful surgery is a rare event, but no clear data are reported in the literature about its recurrence rates. This study aimed to evaluate the recurrence rate in a series of acromegalic patients treated by transsphenoidal surgery (TSS) with a long follow-up.

Methods
We retrospectively analyzed data from 283 acromegalic patients who underwent TSS at two pituitary units in Milan (Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico and IRCCS Humanitas Research Hospital). The diagnosis and recurrence of acromegaly were defined by both elevated IGF-1 levels and a lack of GH suppression based on appropriate criteria for the assay used at the time of diagnosis.

Results
After surgery, 143 patients (50%) were defined as not cured, 132 (47%) as cured and 8 (3%) as partially cured because of normalization of only one parameter, either IGF1 or GH. In the cured group, at the last follow-up (median time 86.8 months after surgery), only 1 patient (0.7%) showed full recurrence (IGF-1 + 5.61 SDS, GH nadir 1.27 µg/l), while 4 patients (3%) showed only increased IGF1. In the partially cured group at the last follow-up, 2/8 (25%) patients showed active acromegaly (IGF-1 SDS + 2.75 and + 3.62; GH nadir 0.6 and 0.5 µg/l, respectively).

Conclusions
In the literature, recurrence rates range widely, from 0 to 18%. In our series, recurrence occurred in 3.7% of patients, and in fewer than 1%, recurrence occurred with elevation of both IGF-1 and the GH nadir. More frequently (25%), recurrence came in the form of incomplete normalization of either IGF-1 or GH after surgery.
Macro-financial policy at the crossroad: addressing climate change, biodiversity loss, and environmental degradation - introduction to the special issue
Authors: D’Orazio Paola , Schäfer Dorothea , Stephan Andreas 
Published: March 2024

AbstractThis special issue of the Eurasian Economic Review delves into the critical relationships between macro-financial policy frameworks and environmental sustainability, emphasizing the urgent challenges posed by climate change, biodiversity loss, and environmental degradation. These environmental crises pose significant threats to global economic and financial stability, underscoring the necessity of integrating environmental considerations into macro-financial policies to foster sustainability and resilience in economic policymaking. Through a collection of research papers, this issue explores innovative strategies for developing comprehensive policy frameworks that harmonize monetary, financial, and fiscal policies with environmental objectives. It emphasizes the need for advanced methods to assess and manage the financial risks of climate change and environmental degradation. Underscoring the need for a multidisciplinary approach, the research advocates for the collaboration of economists, environmental scientists, policymakers, and stakeholders to develop effective macro-financial policies. These policies aim to mitigate environmental risks, enhance environmental sustainability, and preserve biodiversity. The issue calls for further research to refine models that accurately predict the macro-financial impacts of environmental risks and assess the effectiveness of policy measures, paving the way for a sustainable future in the face of escalating environmental challenges.