bluuebunny/crossref_metadata_2025_split huggingface dataset:
The anterior communicating artery variants: a meta-analysis with a proposed classification system
Authors: Triantafyllou George , Tudose Răzvan Costin , Tsiouris Christos , Tsakotos George , Loukas Marios , Tubbs R. Shane , Kalamatianos Theodosis , Chrissicopoulos Christos , Al-Nasraoui Katerina , Koutserimpas Christos , Rusu Mugurel Constantin , Natsis Konstantinos , Kotrotsios Anastasios , Piagkou Maria 
Published: March 2024

AbstractMorphological and morphometric variants of the anterior communicating artery (AComA) have been described by multiple studies; however, a complete classification system of all possible morphological variants with their prevalence is lacking. The current systematic review with meta-analysis combines data from different databases, concerning the AComA morphological and morphometric variants (length and diameter). Emphasis was given to the related clinical implications to highlight the clinical value of their knowledge. The typical AComA morphology occurs with a pooled prevalence (PP) of 67.3%, while the PP of atypical AComA is 32.7%. The identified AComA morphological variants (artery’s hypoplasia, absence, duplication, triplication, differed shape, fenestration, and the persistence of a median artery of the corpus callosum- MACC) were classified in order of frequency. The commonest presented variants were the AComA hypoplasia (8%) and the anterior cerebral artery (ACA) fusion (5.9%), and the rarest ones were the MACC persistence (2.3%), and the AComA triplication (0.7%). The knowledge of those variants is essential, especially for neurosurgeons operating in the area. Given the high prevalence of AComA aneurysms, an adequate and complete classification of those variants is of utmost importance.
Molecular diagnostics of hepatobiliary and pancreatic neoplasias
Authors: Longerich T. , Stenzinger A. , Schirmacher P. 
Published: March 2024

AbstractNeoplasias of the hepatopancreatobiliary tract are growing in numbers, have the poorest prognosis of all major cancer entities, and thus represent a rising clinical problem. Their molecular diagnostic has dramatically improved, contributing to tumor subtyping, definition of malignancy, and uncovering cases with hereditary predisposition. Most of all, predictive molecular testing allows to identify cases amenable to treatment with the rising number of approved targeted drugs, immune-oncological treatment, and clinical trials. In this review, the current state of molecular testing and its contribution to clinical decision-making are outlined.
In-person versus electronic screening for social risks among carers of pediatric inpatients: A mixed methods randomized trial
Authors: Smithers Lisa Gaye , MacPhail Catherine , Chan Lily , Downes Maeve , Neadley Kate , Boyd Mark 
Published: March 2024

AbstractWe aimed to compare disclosure of social risks according to self-report on an iPad versus face-to-face questions from a health professional and to explore carers’ experiences of screening. This two-arm, parallel group, randomized trial was conducted from January 19, 2021, to December 17, 2021, in a public hospital pediatric ward serving a disadvantaged area of an Australian capital city. Carers of children aged ≤ 5 years admitted to the Children’s Ward were eligible. The primary outcome was disclosure of social risks. The screener included nine items on food security, household utilities, transport, employment, personal and neighborhood safety, social support, housing and homelessness. Disclosure of social risks was similar between the self-completion (n = 193) and assisted-completion (n = 193) groups for all 9 items, ranging 4.1% higher for worrying about money for food (95% CI − 11.4, 3.1%) among the assisted-completion group, to 5.7% (−1.6, 13.0%) higher for unemployment among the self-completion group. In qualitative interviews, participants were positive about screening for social risks in the hospital ward setting and the majority indicated a preference for self-completion. Conclusion: Differences in the disclosure of social risks according to self- versus assisted-completion were small, suggesting that either method could be used. Most carers expressed a preference for self- completion, which is therefore recommended as the ideal mode for such data collection for Australian pediatric inpatient settings. Trial registration: Australia New Zealand Clinical Trial Registry (www.anzctry.org.au; #ACTRN12620001326987; date of registration 8 December 2020).

What is Known:• Most evidence on screening of social risks in pediatric inpatient settings is from the USA.• Little is known about disclosure of social risks in countries with universal health care and social welfare.

What is New:• Disclosure of social risks was similar for electronic compared with face-to-face screening.• Carers preferred electronic completion over face-to-face completion.
Investigating maternal and neonatal health outcomes associated with continuing or ceasing dexamphetamine treatment for women with attention-deficit hyperactivity disorder during pregnancy: a retrospective cohort study
Authors: Russell Danielle J. , Wyrwoll Caitlin S. , Preen David B. , Kelty Erin 
Published: March 2024

Abstract
Purpose
Attention-deficit hyperactivity disorder (ADHD) is becoming more commonly diagnosed in women, consequently, more women of reproductive age are taking ADHD medication, such as dexamphetamine. However, the safety associated with continuing or ceasing dexamphetamine during pregnancy is unclear. This study investigates outcomes associated with the continuation of dexamphetamine during pregnancy compared to those who ceased or were unexposed.

Methods
A population-based retrospective cohort of women from Western Australia who had been dispensed dexamphetamine during pregnancy and gave birth between 2003 and 2018. Women had either continued to take dexamphetamine throughout pregnancy (continuers, n = 547) or ceased dexamphetamine before the end of the second trimester (ceasers, n = 297). Additionally, a matched (1:1) comparison group of women who were dispensed an ADHD medication prior to pregnancy but not during pregnancy (unexposed) was included in the study (n = 844). Multivariable generalised linear models were used to compare maternal and neonatal health outcomes.

Results
Compared to continuers, ceasers had greater odds of threatened abortion (OR: 2.28; 95%CI: 1.00, 5.15; p = 0.049). The unexposed had some benefits compared to the continuers, which included lower risk of preeclampsia (OR: 0.58; 95%CI: 0.35, 0.97; p = 0.037), hypertension (OR: 0.32; 95%CI: 0.11, 0.93; p = 0.036), postpartum haemorrhage (OR: 0.57; 95%CI: 0.41, 0.80; p = 0.001), neonatal special care unit admittance (OR: 0.16; 95%CI: 0.12, 0.20; p < 0.001) and fetal distress (OR: 0.73; 95%CI: 0.54, 0.99; p = 0.042).

Conclusion
Continuing dexamphetamine throughout pregnancy was not associated with an increase in adverse neonatal and maternal health outcomes compared to ceasing. Ceasing dexamphetamine during pregnancy was associated with increased odds of threatened abortion compared with continuing dexamphetamine. However, this is something that requires further investigation due to the small sample size, difficulties examining timing, and the inability to examine spontaneous abortions. The unexposed showed some benefits compared to the continuers, suggesting that where possible the cessation of dexamphetamine prior to pregnancy may be advisable.
Plastic deformation effect on contact behaviour in granular materials
Authors: Altuhafi F. N. , Baudet B. A. , Coop M. R. 
Published: March 2024

AbstractContact tests on machined and natural granite showed that extensive plastic deformation which extends to the core shape is happening before the cross-over from the behaviour of an elastic rough surface to the Hertzian behaviour of an elastic smooth contact when all asperities have yielded in the surface. The plastic deformation, which was found to take place when the estimated maximum stresses at the contact reaches about 0.6 of the material hardness, affects the behaviour during normal loading as the material will start to deform at constant stiffness after reaching these stresses. The plastic deformation during lateral loading also affects the applicability of lateral loading models. The data yielded a much lower lateral stiffness which is around one order of magnitude less than that predicted by the available contact models.
Hereditary spastic paraparesis type 18 (SPG18): new ERLIN2 variants in a series of Italian patients, shedding light upon genetic and phenotypic variability
Authors: Cioffi Ettore , Gioiosa Valeria , Tessa Alessandra , Petrucci Antonio , Trovato Rosanna , Santorelli Filippo Maria , Casali Carlo 
Published: March 2024

Abstract
Introduction
Hereditary spastic paraparesis (HSP) is a group of central nervous system diseases primarily affecting the spinal upper motor neurons, with different inheritance patterns and phenotypes. SPG18 is a rare, early-onset, complicated HSP, first reported as linked to biallelic ERLIN2 mutations. Recent cases of late-onset, pure HSP with monoallelic ERLIN2 variants prompt inquiries into the zygosity of such genetic conditions. The observed relationship between phenotype and mode of inheritance suggests a potential dominant negative effect of mutated ERLIN2 protein, potentially resulting in a milder phenotype. This speculation suggests that a wider range of HSP genes could be linked to various inheritance patterns.

Purpose and background
With documented cases of HSP loci exhibiting both dominant and recessive patterns, this study emphasizes that the concept of zygosity is no longer a limiting factor in the establishment of molecular diagnoses for HSP. Recent cases have demonstrated phenoconversion in SPG18, from HSP to an amyotrophic lateral sclerosis (ALS)-like syndrome.

Methods and results
This report highlights two cases out of five exhibiting HSP-ALS phenoconversion, discussing an observed prevalence in autosomal dominant SPG18. Additionally, the study emphasizes the relatively high incidence of the c.502G>A variant in monoallelic SPG18 cases. This mutation appears to be particularly common in cases of HSPALS phenoconversion, indicating its potential role as a hotspot for a distinctive SPG18 phenotype with an ALS-like syndrome.

Conclusions
Clinicians need to be aware that patients with HSP may show ALS signs and symptoms. On the other hand, HSP panels must be included in genetic testing methods for instances of familial ALS.
Potassium transporter OsHAK17 may contribute to saline-alkaline tolerant mechanisms in rice (Oryza sativa)
Authors: Nampei Mami , Ogi Hiromu , Sreewongchai Tanee , Nishida Sho , Ueda Akihiro 
Published: March 2024

AbstractRice production is seriously affected by saline-alkaline stress worldwide. To elucidate the saline-alkaline tolerance mechanisms in a novel tolerant rice variety, Shwe Nang Gyi (SNG), we investigated ion accumulation in SNG and Koshihikari (KSH), which is a saline-alkaline sensitive rice variety, and the candidates for saline-alkaline inducible genes in SNG using RNA-seq. SNG had superior ion accumulation capacity, such as K and Zn, compared to KSH. In contrast, SNG accumulated the same level of Na content in its leaf blades as KSH despite the higher dry weight of the SNG leaf blades. We further found that the expression of numerous genes, including several K+ transporter/high-affinity K+ transporter/K+ uptake protein/K+ transporter (HAK/KUP/KT) family members, were upregulated in SNG, and that OsHAK17 and OsHAK21 expression levels in the roots were significantly higher in SNG than in KSH. Moreover, yeast complementation analysis revealed that OsHAK17 was involved in K+ uptake under high-Na conditions. These results suggested that SNG has an effective K+ acquisition system supported by OsHAK17 functioning in saline-alkaline environments.
Compatible relative open books on relative contact pairs via generalized square bridge diagrams
Authors: Arıkan M. F. , Taşpınar İ. Ö. 
Published: March 2024

AbstractUsing square bridge position, Akbulut-Ozbagci and later Arikan gave algorithms both of which construct an explicit compatible open book decomposition on a closed contact 3-manifold which results from a contact $$(\pm 1)$$

(
±
1
)

-surgery on a Legendrian link in the standard contact 3-sphere. In this article, we introduce the “generalized square bridge position” for a Legendrian link in the standard contact 5-sphere and partially generalize this result to the dimension five via an algorithm which constructs relative open book decompositions on relative contact pairs.
Promoting the adoption of climate-smart agricultural technologies among maize farmers in Ghana: using digital advisory services
Authors: Asante Bright O. , Ma Wanglin , Prah Stephen , Temoso Omphile 
Published: March 2024

AbstractAlthough policy and advisory communities have promoted the use of digital advisory services (DAS) to stimulate technology adoption among smallholder farmers, little is known about whether DAS use encourages farmers to adopt climate-smart agricultural (CSA) technologies. This study addresses the gap by estimating data collected from 3197 maize-producing households in rural Ghana and considering three CSA technologies: row planting, zero tillage, and drought-tolerant seeds. A recursive bivariate probit model is utilized to mitigate selection bias issues. The results show that DAS use significantly increases the probabilities of adopting row planting, zero tillage, and drought-tolerant seeds by 12.4%, 4.2%, and 4.6%, respectively. Maize farmers’ decisions to use DAS are influenced by their age, gender, education, family size, asset value, distance to farm, perceived incidence of pest and disease, perceived drought stress, and membership in farmer-based organizations (FBO). Furthermore, the disaggregated analysis reveals that DAS use has a larger impact on the row planting adoption of female farmers than males.
MDS, Hermitian almost MDS, and Gilbert–Varshamov quantum codes from generalized monomial-Cartesian codes
Authors: Barbero-Lucas Beatriz , Hernando Fernando , Martín-Cruz Helena , McGuire Gary 
Published: March 2024

AbstractWe construct new stabilizer quantum error-correcting codes from generalized monomial-Cartesian codes. Our construction uses an explicitly defined twist vector, and we present formulas for the minimum distance and dimension. Generalized monomial-Cartesian codes arise from polynomials inmvariables. When$$m=1$$m=1our codes are MDS, and when$$m=2$$m=2and our lower bound for the minimum distance is 3, the codes are at least Hermitian almost MDS. For an infinite family of parameters, when$$m=2$$m=2we prove that our codes beat the Gilbert–Varshamov bound. We also present many examples of our codes that are better than any known code in the literature.
Life cycle assessment of a LiFePO4 cylindrical battery
Authors: Botejara-Antúnez Manuel , Prieto-Fernández Alejandro , González-Domínguez Jaime , Sánchez-Barroso Gonzalo , García-Sanz-Calcedo Justo 
Published: March 2024

AbstractReduction of the environmental impact, energy efficiency and optimization of material resources are basic aspects in the design and sizing of a battery. The objective of this study was to identify and characterize the environmental impact associated with the life cycle of a 7.47 Wh 18,650 cylindrical single-cell LiFePO4 battery. Life cycle assessment (LCA), the SimaPro 9.1 software package, the Ecoinvent 3.5 database and the ReCiPe 2016 impact assessment method were used for this purpose. Environmental impacts were modelled and quantified using the dual midpoint-endpoint approach and the “cradle-to-gate” model. The results showed the electrodes to be the battery components with the highest environmental impact (41.36% of the total), with the negative electrode being the most unfavourable (29.8 mPt). The ageing, calibration and testing process (53.97 mPt) accounts for 97.21% of the total impact associated with the production process’s consumption of energy, and 41.20% of the total impact associated with the battery. This new knowledge will allow a more detailed view of the environmental impact of cylindrical cell LiFePO4 batteries, favouring the identification of critical points to enhance their sustainable production.
Self-selected versus imposed running intensity and the acute effects on mood, cognition, and (a)periodic brain activity
Authors: Braunsmann Leonard , Beermann Finja , Strüder Heiko K. , Abeln Vera 
Published: March 2024

AbstractThe beneficial psychological effects of exercise might be explained by self-determination theory and autonomy. However, the underlying neurophysiological mechanisms are even less elucidated. Previously neglected, aperiodic (1/f) brain activity is suggested to indicate enhanced cortical inhibition when the slope is steeper. This is thought to be associated with an increased cognitive performance. Therefore, we hypothesize that running with a self-selected intensity and thus given autonomy leads to stronger neural inhibition accompanied by psychological improvements. Twenty-nine runners performed two 30-min runs. First, they chose their individual feel-good intensity (self-selected run; SR). After a 4-weeks washout, the same speed was blindly prescribed (imposed run; IR). Acute effects on mood (Feeling Scale, Felt Arousal Scale, MoodMeter®), cognition (d2-R, digit span test) and electrocortical activity (slope, offset, 1/f-corrected alpha and low beta band) were analyzed before and after the runs. Both runs had an equal physical workload and improved mood in the Felt Arousal Scale, but not in the Feeling Scale or MoodMeter®. Cognitive performance improved after both runs in the d2-R, while it remained stable in the digit span test after SR, but decreased after IR. After running, the aperiodic slope was steeper, and the offset was reduced. Alpha activity increased after SR only, while low beta activity decreased after both conditions. The aperiodic features partially correlated with mood and cognition. SR was not clearly superior regarding psychological effects. Reduced aperiodic brain activity indicates enhanced neural inhibition after both runs. The 1/f-corrected alpha band may emphasize a different neural processing between both runs.
An In Vitro Study for the Role of Schizophrenia-Related Potential miRNAs in the Regulation of COMT Gene
Authors: Tonk Onur , Tokgun Pervin Elvan , Yılmaz Özge Sarıca , Tokgun Onur , Inci Kubilay , Çelikkaya Büşra , Altintas Nuray 
Published: March 2024

AbstractThis study aimed to analyze the possible association of miR-30a-5p, miR-30e-5p, and miR-34a-5p identified as potential candidate miRNAs in schizophrenia, with the COMT gene. Candidate miRNAs were obtained from the TargetScan database. The SH-SY5Y human neuroblastoma cell line was used as a cellular model for schizophrenia. miR-30a-5p, miR-30e-5p, and miR-34a-5p mimics were transfected into the SH-SY5Y cell line. Total RNA was isolated from transfected cells and RNA-IP samples and reverse transcripted for miRNA and mRNA analysis. RT-qPCR and western blot were performed to observe changes in expression levels of COMT. RNA-ımmunoprecipitation was performed to determine RNA–protein interactions after mimic transfection. In the study, it was observed that COMT gene expression levels decreased significantly after miR-30a-5p and miR-34a-5p expressions, whereas increased significantly as a result of miR-30e-5p transfection. RNA-IP data have shown that the amount of COMT pulled down by Ago2 was increased after miR-30a-5p and miR-34a-5p transfections. RNA-IP results revealed that miR-30a-5p and miR-34a-5p are direct targets for the COMT gene.
Economic Risk Assessment of Future Debris Flows by Machine Learning Method
Authors: Qiu Chenchen , Su Lijun , Pasuto Alessandro , Bossi Giulia , Geng Xueyu 
Published: March 2024

AbstractA reliable economic risk map is critical for effective debris-flow mitigation. However, the uncertainties surrounding future scenarios in debris-flow frequency and magnitude restrict its application. To estimate the economic risks caused by future debris flows, a machine learning-based method was proposed to generate an economic risk map by multiplying a debris-flow hazard map and an economic vulnerability map. We selected the Gyirong Zangbo Basin as the study area because frequent severe debris flows impact the area every year. The debris-flow hazard map was developed through the multiplication of the annual probability of spatial impact, temporal probability, and annual susceptibility. We employed a hybrid machine learning model—certainty factor-genetic algorithm-support vector classification—to calculate susceptibilities. Simultaneously, a Poisson model was applied for temporal probabilities, while the determination of annual probability of spatial impact relied on statistical results. Additionally, four major elements at risk were selected for the generation of an economic loss map: roads, vegetation-covered land, residential buildings, and farmland. The economic loss of elements at risk was calculated based on physical vulnerabilities and their economic values. Therefore, we proposed a physical vulnerability matrix for residential buildings, factoring in impact pressure on buildings and their horizontal distance and vertical distance to debris-flow channels. In this context, an ensemble model (XGBoost) was used to predict debris-flow volumes to calculate impact pressures on buildings. The results show that residential buildings occupy 76.7% of the total economic risk, while road-covered areas contribute approximately 6.85%. Vegetation-covered land and farmland collectively represent 16.45% of the entire risk. These findings can provide a scientific support for the effective mitigation of future debris flows.
Georg Ebers’ Professorenromane und die frühe Ägyptologie
Authors: Lickhardt Maren 
Published: March 2024

ZusammenfassungGeorg Ebers’ wirkliche oder vermeintliche Popularität auf Basis eines historischen Romans über das alte Ägypten trägt zur Etablierung bzw. Ausweitung ägyptologischer Lehrstühle in Deutschland bei. Der Artikel arbeitet heraus, warum der Roman populär war, und vollzieht besagten Etablierungsprozess nach. Anschließend wird Ebers’ zweifache Entpopularisierung untersucht. Zum einen eignet sich sein Roman aufgrund seiner literarästhetisch ›populären‹ Signatur wenig zur Kanonisierung. Zum anderen trägt Ebers’ Schüler Adolf Erman zu einer endgültigen Ausdifferenzierung und Spezialisierung des Fachs bei, indem er eine Schließung vornimmt und die populäre Außenseite der Ägyptologie samt Ebers abschneidet.