bluuebunny/crossref_metadata_2025_split huggingface dataset:
Synthesis, complexation and antifungal, antibacterial activity studies of a new macrocyclic schiff base
Authors: Ugras H. Ibrahim , Basaran Ismet , Kilic Turgut , Cakir Umit 
Published: March 2009

Abstractmagnified imageA new macrocyclic ligand, L was synthesized using the high dilution condition with condensation of triethylene glycol diamine and terephtalaldehyde in ethanol. The obtained product, L was identified by FT‐IR, 1H‐NMR, 13C‐NMR and Mass spectroscopy. The extraction equilibrium constants were estimated using dichloromethane/water membranes transfer with ICP‐AES and AES spectroscopy. Biological studies of this compound was determinated with disc diffusion method. The biological activity results showed that the synthesized ligand L has high activity against the studied microorganisms and high complexation ability against the Fe2+ cation.
First synthesis of furo[3,4‐c]coumarins
Authors: Brahmbhatt Dinker I. , Gajera Jitendra M. , Patel Chirag N. , Pandya Vishwesh P. , Pandya Urvish R. 
Published: March 2009

Abstractmagnified imageVarious 1,3‐dimethyl and 1‐methyl‐3‐phenylfuro[3,4‐c]coumarins (5a‐h and 6a‐h) have been synthesized by demethylation cyclization of the respective 3‐aryl‐4‐ethoxycarbonyl furans (3a‐h and 4a‐h). These ethoxycarbonyl furans were prepared by reacting appropriate 1‐aryl‐2‐nitro‐prop‐1‐ene (1a‐h) with ethyl acetoacetate or ethyl benzoylacetate under Nef reaction condition.
Chemical properties of pyrimidoquinoxaline 6‐oxides
Authors: García Ma. Beatriz , Orelli Liliana R. , Perillo Isabel A. 
Published: March 2009

Abstractmagnified imageThe reactivity of some representative 5‐arylpyrimidoquinoxaline 6‐oxides 1 was investigated. Reduction with sodium borohydride afforded the corresponding N‐deoxy compounds 2. Reaction with methyl iodide in excess led selectively to N‐methyl derivatives 3. The preference for N vs. O‐alkylation is analyzed considering electronic effects. Alkaline hydrolysis of compounds 1 involved initial nucleophilic attack to the amidine carbon (C4a), and subsequent regioselective ring opening leading to 4‐(3‐aminopropyl)‐2‐aryl‐quinoxaline‐3‐one 1‐oxides 4. The regioselectivity observed in alkaline hydrolysis is also discussed.
Microwave‐accelerated synthesis of benzyl 3,5‐dimethyl‐pyrrole‐2‐carboxylate
Authors: Regourd Jasmine , Comeau Ian M. , Beshara Cory S. , Thompson Alison 
Published: March 2009

Abstractmagnified imageBenzyl 3,5‐dimethyl‐pyrrole‐2‐carboxylate, a very useful pyrrole in porphyrin and dipyrromethene synthesis, can be synthesized via the Knorr‐type reaction, but in low yield. Alternative routes to benzyl 3,5‐dimethyl‐pyrrole‐2‐carboxylate have been developed involving the trans‐esterification of ethyl 3,5‐dimethyl‐pyrrole‐2‐carboxylate and the de‐acetylation of benzyl 4‐acetyl‐3,5‐dimethyl‐2‐carboxylate, both precursors being easily obtained using the Knorr reaction. These traditional methods involve treatment of the known products with a strong basic solution or heating for extended periods which often lead to decomposition. The use of microwave energy to promote these two reactions proves to be an extremely efficient way to obtain benzyl 3,5‐dimethyl‐pyrrole‐2‐carboxylate quickly, in high yield, and in excellent purity with no need for recrystallization. Of particular note is the use of catalytic sodium methoxide in benzyl alcohol, rather than stoichiometric amounts of sodium benzoxide, to effect benzylation.
A facile regioselective synthesis of (5‐amino‐4‐cyano‐1h‐imidazol‐1‐yl) benzoic acids
Authors: Barros Síria A. , Gonçalves M. Sameiro T. , Oliveira‐Campos Ana M. F. , Proença Fernanda R. P. 
Published: March 2009

Abstractmagnified imageA simple and efficient method was developped for the synthesis of 3‐(5‐amino‐4‐cyano‐1H‐imidazol‐1‐yl)‐4‐substituted benzoic acids 3. These compounds were isolated by intramolecular cyclisation of the corresponding 3‐{[(Z)‐2‐amino‐1,2‐dicyano‐vinyl]amino}methyleneaminobenzoic acids in the presence of base.
Synthesis of some thiazolyl and thiadiazolyl derivatives of substituted furan and pyrrole
Authors: Hassan Seham Y. 
Published: March 2009

Abstractmagnified imageFour series of substituted furan and pyrrole have been synthesized. The first series was prepared by cyclization of the key intermediates ethyl 5‐[(4‐substituted thiosemicarbazido)methyl]‐2‐methylfuran‐3‐carboxylates 2a‐2d and 1‐[(4‐acetyl‐5‐methyl‐1H‐pyrrol‐2‐yl)methylene]‐4‐substituted thiosemicarbazides 8a‐8d with chloroacetic acid or (ethyl bromoacetate) to afford the corresponding 4‐oxo‐3‐substituted thiazolidin‐2‐ylidene 3a‐3d or 3‐substituted thiazolidin‐4‐one 9a‐9d. On the other hand, heating of the intermediates 2a‐2d or 8a‐8d with acetic anhydride afforded the corresponding (N‐substituted acetylamino)‐2,3‐dihydro‐[1,3,4]thiadiazol‐2‐yl derivatives 4a‐4d and [1,3,4]thiadiazol‐2‐yl‐N‐substituted acetamide 10a‐10d respectively, while cyclization with p‐bromophenacyl bromide gave rise to the corresponding 3‐substituted thiazol‐2‐yl‐ylidene 5a‐5d and 11a‐11d respectively. Furthermore, 4‐oxo‐3‐substituted thioureido‐thiazolidin‐2‐yl 6a‐6d or 4‐oxo‐thiazolidin‐3‐yl‐3‐substituted thiourea 12a‐12d were obtained by reaction of the intermediates 2a‐2d or 8a‐8d with thioglycolic acid. Some of the synthesized compounds showed promising antimicrobial activities.
Synthesis and antimicrobial activity of novel spirocompounds with pyrazolone and pyrazolthione moiety
Authors: Chande Madhukar S. , Barve Pravin A. , Suryanarayan Vijay 
Published: March 2009

Abstractmagnified imageThe paper focuses on the utility of 2‐pyrazoline‐5‐ones and 2‐pyrazoline‐5‐thiones as active Michael donors for the synthesis of novel spirocyclohexanone derivatives. The sulphur containing compounds when screened for antimicrobial activity showed promising inhibition of S. Typhi, S Aures and E Coli bacteria.
Thio analogs of pyrimidine bases: Syntheses and EIMS study of new ortho‐(meta‐ and para‐)bromobenzyl s‐mono and S‐N‐1‐disubstituted 5‐morpholinomethyl(5‐piperidinomethyl)‐2‐thiouracils
Authors: Wyrzykiewicz Elżbieta , Pospieszny Tomasz 
Published: March 2009

Abstractmagnified imageEleven new ortho‐(meta‐ and para‐)bromobenzyl S‐mono and S‐N‐1‐disubstituted derivatives of 5‐morpholinomethyl‐2‐thiouracil (MMTU) and 5‐piperidinomethyl‐2‐thiouracil (PMTU) have been prepared and their EI induced mass spectral fragmentation has been investigated. It has been shown that the data derived from EIMS spectra can be used to differentiate the isomers
New reaction of schiff base with dimedone: New method for the acridine derivatives under microwave irradiation
Authors: Tu Shujiang , Li Tuanjie , Zhang Yan , Shi Feng , Xu Jianing , Wang Qian , Zhang Jinpeng , Zhu Xiaotong , Jiang Bo , Jia Runhong , Zhang Junyong 
Published: March 2009

Abstractmagnified imageA novel cascade reaction of Schiff's base was described. The products afforded in the reaction depended on the ratio of the two starting materials. A possible mechanism of the reactions is proposed, which underwent the breaking and new formation of the bond between carbon atom and nitrogen atom.
Synthesis of 1,4‐disubstituted 1,2,3‐triazoles via a three‐component reaction in water in the presence of cux (X = Cl, I)
Authors: Wang Zhong‐Xia , Zhao Zhi‐Gang 
Published: March 2009

Abstractmagnified imageThree‐component reaction of alkyl halides, sodium azide and alkynes in water in the presence of CuX (X = Cl, I) afforded 1,4‐disubstituted 1,2,3‐triazoles in high yields. These reactions do not require any special precautions or existence of a reducing agent. The bistriazoles formed during the reaction can efficiently enhance the catalytic activity of the Cu(I) salts.
Synthesis of propionamide pyridine and pyridine n‐oxide ligands
Authors: Binyamin Iris , Pailloux Sylvie , Duesler Eileen N. , Paine Robert T. , Hay Benjamin P. , Rapko Brian M. 
Published: March 2009

Abstractmagnified imageA new set of pyridine and pyridine N‐oxides functionalized with N,N‐dimethylpropionamide pendant groups in the 2‐ and 2,6‐positions have been prepared from the combination of 2‐chloromethylpyridine and 2,6‐bis(chloromethyl) pyridine with α‐lithio N,N‐dimethyl acetamide. The coordination interaction between 2‐(N,N‐dimethylpropionamide) pyridine N‐oxide (10) and Tb(NO3)3 has been unambiguously defined via single crystal X‐ray diffraction analysis of Tb(10)(NO3)3(H2O).
Synthesis of novel 3,5,7‐triaryl‐5,6‐dihydro‐4h‐1,2,5‐triazepines
Authors: Ravindran Gurusamy , Muthusubramanian Shanmugam , Selvaraj Sanguvan , Perumal Subbu 
Published: March 2009

Abstractmagnified imageSeveral hitherto unknown 3,5,7‐triaryl‐5,6‐dihydro‐4H‐1,2,5‐triazepines have been synthesised by cyclocondensation of N,N‐bis(phenacyl)anilines with hydrazine hydrate in ethanol or ethyleneglycol under reflux condition. Increased yields were obtained in the presence of p‐toluenesulfonic acid compared to the uncatalysed reaction.
1,3‐Dipolar cycloadditions: Investigation of cycloadditions of c‐aryl‐n‐(4‐chlorophenyl) nitrones to n‐cinnamoyl piperidines
Authors: Banerji Avijit , Biswas Pizush Kanti , Bandyopadhyay Debasish , Gupta Maya , Prangé Thierry , Neuman Alain 
Published: March 2009

Abstractmagnified imageInvestigation of cycloadditions of C‐aryl‐N‐(4‐chlorophenyl)nitrones to N‐cinnamoyl piperidines was carried out. Two diastereoisomeric and one regioisomeric cycloadducts, and in some cases ring‐opened compounds were characterized by spectroscopic and X‐ray data. Molecular modelling was carried out for conformational studies.
Synthesis and structure elucidation of 3,4‐dihydroxy‐2‐quinolin‐2‐ylpyrido[3,2,1‐jk]carbazol‐6‐ones
Authors: Dang Hoai V. , Habib Nargues S. , Kappe Thomas , Zangger Klaus , Stadlbauer Wolfgang 
Published: March 2009

Abstractmagnified image3,4‐Dihydroxy‐2‐quinolin‐2‐ylpyrido[3,2,1‐jk]carbazol‐6‐ones 6 were obtained by cyclocondensation of carbazole 1 with malonates 2 in the presence of quinoline. The assignment of the structures of 6 was performed by NMR experiments such as 1D 1H, 13C and DEPT, as well as 2D COSY, HSQC, HMBC and 1,1‐ADEQUATE spectra.
Synthesis of crown ethers bearing 2,4‐dinitrophenylhydrazone
Authors: Abdurrahmanoglu Saziye , Bulut Mustafa 
Published: March 2009

Abstractmagnified imageThe o‐dihydroxy‐ (2a‐b), dimethoxy (3a‐b), ethylendioxy‐ (4a‐b) and macrocyclic polyethers (4c‐i) are the initial compounds while the 2,4‐dinitrophenylhydrazone compounds (5a‐d, 6a‐i) represent new derivatives. Novel hydrazone compounds were synthesized from the corresponding cyclic ketones (4a‐i) and 2,4‐dinitrophenylhydrazine in H2SO4/EtOH/H2O solution at room temperature for 1 h. The structures of obtained hydrazone compounds were confirmed by 1H‐NMR, 13C‐NMR, EI‐MS, IR spectra and elemental analysis.
Phase transfer catalyzed synthesis of 3‐methyl‐4h‐pyrazolo[3,4‐d]isoxazole from 3,5‐dimethyl‐4‐isoxazolyldiazonium tetrafluoroborate
Authors: Rajanarendar E. , Mohan G. , Ramesh P. , Srinivas M. 
Published: March 2009

Abstractmagnified imageReaction of 3,5‐dimethyl‐4‐isoxazolyl‐diazonium tetrafluoroborate (2) with two equivalents of potassium acetate and five mole percent of 18‐crown‐6 in ethanol‐free chloroform produce 3‐methyl‐4H‐pyrazolo[3,4‐d]isoxazole (3) in good to excellent yield. Pyrazole (3) was subjected to acylation/aroylation to afford the corresponding 4‐N‐acetyl/aroyl derivatives by reaction with CH3COCl/ArCOCl in Et3N.
Flash vacuum pyrolysis of 1‐azolyl‐1‐phenylhydrazono‐2‐propanones
Authors: El‐Dusouqui Osman M. E. , Dib Hicham H. , Al‐Awadi Nouria A. , Abdelkhalik Mervat M. , Al‐Etaibi Alya M. 
Published: March 2009

Abstractmagnified imageFlash vacuum pyrolysis (FVP) of 1‐(2‐arylhydrazono)‐1‐(1H‐1,2,4‐triazol‐1‐yl)acetone 8a‐c at 650 °C and 2.67 Pa yielded 5‐substituted 1‐(1H‐indazol‐3‐yl)ethanone 14a‐c and 4,6‐disubstituted cinnoline 18a‐c. Similarly FVP of 1‐(1H‐benzo[d]imidazol‐1‐yl)‐1‐(2‐phenylhydrazono)acetone 9a‐c gave 8H‐benzo[4′,5′]imidazo[2′,1′:5,1]pyrrolo[2,3‐c]cinnoline derivatives 23a‐c. A plausible mechanism is suggested to account for their transformation based on the kinetics and products of reaction.
Synthesis of α‐diaminomethylenebutyrolactams by the reaction of α‐cyanobutyrolactams with n‐trimethylsilylamines
Authors: Okabe Fumi , Nakamura Syouhei , Yamagata Kenji 
Published: March 2009

Abstractmagnified imageSuccessive treatment of α‐cyanobutyrolactams 1 with N‐trimethylsilylamines and water gave the corresponding α‐diaminomethylenebutyrolacatms 2 in good yields. In the NOESY spectra of 2, the E isomer, the NOE observed between β‐CH2 (butyrolactam) and N‐CH2 (morpholine, pyrrolidine) or N‐CH3 (dimethylamine) indicated a cis configuration of these groups.
Regiospecific synthesis of trichloromethyl substituted 4,5‐dihydro‐1h‐1‐tosylpyrazoles
Authors: Bonacorso Helio G. , Wentz Alexandre P. , Lourega Rogério V. , Cechinel Cleber A. , Moraes Tatiana S. , Flores Alex F. C. , Zanatta Nilo , Martins Marcos A. P. 
Published: March 2009

Abstractmagnified imageThe regiospecific synthesis of a new series of eight 3‐alkyl(aryl)‐5‐hydroxy‐5‐trichloromethyl‐4,5‐dihydro‐1H‐1‐tosylpyrazoles is reported. The 1‐p‐tosyl‐2‐pyrazolines were obtained from the cyclocondensation reaction of 4‐alkyl(aryl)‐4‐alkoxy‐1,1,1‐trichloroalk‐3‐en‐2‐ones, [where alkyl = H, Me and aryl = ‐C6H5, 4‐CH3C6H4, 4‐OCH3C6H4, 4‐FC6H4, 4‐ClC6H4, 4‐BrC6H4,] with p‐tosylhydrazine in 64 to 92 % yields, employing anhydrous toluene at reflux or diethyl ether at room temperature as the reaction condition.
Azulene‐substituted pyridines and pyridinium salts. Synthesis and structure. 2. Azulene‐substituted pyridinium salts
Authors: Razus Alexandru C. , Birzan Liviu , Pavel Claudia , Lehadus Oana , Corbu Andreea , Chiraleu Filip , Enache Cristian 
Published: March 2009

Abstractmagnified image4‐Azulen‐1‐yl substituted 2,6‐dimethyl‐and 2,6‐diphenyl‐pyridinium salts are obtained in yields between 50 % and 100 % in the reaction of corresponding 4‐azulen‐1‐yl‐pyranylim salts and various amines. The effects of amine structure and of substitution in the heterocycle or at azulene moieties on the synthesis have been investigated. The uv‐vis and NMR spectra of reaction products are examined and discussed in correlation with their structure.
Preparation of 5‐methyl‐2‐sulfanyl‐7h‐1,3,4‐thiadiazolo[3,2‐a]‐pyrimidin‐7‐ones
Authors: Safarov Saifidin , Kukaniev Muhamacho A. , Karpuk Elena , Meier Herbert 
Published: March 2009

Abstractmagnified image7H‐1,3,4‐Thiadiazolo[3,2‐a]pyrimidin‐7‐ones can be prepared by the acylation of 5‐amino‐1,3,4‐thiadiazoles with diketene and subsequent ring closure (dehydration). Whereas arylthio substituents (SC6H5) can be introduced in 2‐position by the replacement of Br, alkylthio groups (SC2H5) have to be already presentin the starting 5‐amino‐1,3,4‐thiadiazole. The ambident nucleophile 2‐thiazolidinethione reacts in the Br substitution reaction on the N atom.
An improved synthesis of 1‐acetyl‐1H‐indol‐3‐yl acetates
Authors: Rodríguez‐Domínguez Juan C. , Balbuzano‐Deus Alexander , López‐López Miguel A. , Rodríguez‐Domínguez Juan C. , Kirsch Gilbert 
Published: March 2009

Abstractmagnified imageAn efficient two steps procedure for the synthesis of 1‐acetyl‐1H‐indol‐3‐yl acetates, starting from 2‐chlorobenzoic acids, was developed and in general, moderate to good yields were obtained
Synthesis and characterization of some important indazolyl derivatives
Authors: Kale S. B. , Karale B. K. 
Published: March 2009

Abstractmagnified imageA series of some important indazolyl derivatives of pyrazoles, diazepines, thiopyrimidines, thiazines and chromones were synthesized and characterized with the help of spectral data. Some of the synthesized compounds are tested for antimicrobial and antioxidant activities.
Substituted quinolinones. Part 13 a convenient route to heterocyclization reactions with 3‐substituted 4‐hydroxyquinolin‐2(1H)‐one
Authors: Abdel‐Megid Mohamed , Abass Mohamed , Hassan Mohamed 
Published: March 2009

Abstractmagnified imageThe reactivity of 3‐[(dimethylamino)prop‐2‐enoyl]‐4‐hydroxyl‐1‐methylquinolin‐2(1H)‐one (2) towards different nucleophilic and electrophilic reagents was investigated. The convenient synthesis of several 3‐heterocyclyl‐quinolinones such as 3‐pyridazinyl‐ 10, 11, 3‐pyranyl 19a,b and 3‐pyrazolylquinolinones 20a,b, 22, 26a,b, 27a,b, 31 and 33 has been described starting from the 3‐acetylquinolinone 1 and enaminone 2. In addition, certain heterocyclo[c]quinolinones such as pyrimido‐ 12, 14 pyrano‐ 3, 17a,b and pyrazolopyranoquinolinone 29 were obtained in good yields.
Chemical properties of 4,5‐di(ethoxycarbonyl)‐1,3‐dioxolan‐2‐yl (DECDO) as a hydroxyl protecting group of the 2′‐hydroxyl function in ribonucleosides
Authors: Karwowski Boleslaw , Seio Kohji , Sekine Mitsuo 
Published: March 2009

Abstractmagnified imageWe describe basic chemical properties of 4,5‐di(ethoxycarbonyl)‐1,3‐dioxolan‐2‐yl (DECDO) in view of its use as a protecting group for the 2′‐hydroxyl function of ribonucleosides. The DECDO group is found to be compatible with the DMTr strategy for the currently‐used oligonucleotide synthesis. Post‐synthetic treatment with ammonia results in the conversion of this protecting group into the 4,5‐dicarbamoyl‐1,3‐dioxolan‐2‐yl (DCBDO) group which is unexpectedly more stable in aqueous acidic solution.
A study on chemical behaviors of some 4‐pyrones synthesized by one‐step reactions towards various amines
Authors: Şener Ahmet , Eskinoba Siddik , Bildirici İshak , Genç Hasan , Kasimoǧullari Rahmi 
Published: March 2009

Abstractmagnified imageCycloaddition of acetylbenzoyl ketene generated in situ as an intermediate during one‐step reaction between excess benzoylacetone and oxalylchloride to C=C double bond of cyclic enol form of benzoylacetone gave 3‐acetyl‐5‐benzoyl‐6‐methyl‐2‐phenyl‐4(4H)‐pyrone 1a. Condensation reactions of 1a together with 3,5‐dibenzoyl‐2,6‐diphenyl‐4(4H)‐pyrone 1b and 3‐benzoyl‐5‐ethoxycarbonyl‐2,6‐diphenyl‐4(4H)‐pyrone 1c with two‐fold excess primary amines provided a series of 3‐benzoyl‐1‐alkyl‐5‐(1‐alkylimino‐ethyl)‐6‐phenyl‐2‐methyl‐4(1H)‐pyridinone 2, 3,5‐dibenzoyl‐1‐alkyl‐2,6‐diphenyl‐4(1H)‐pyridinone 3a‐c and 3‐benzoyl‐1‐alkyl‐5‐ethoxycarbonyl‐2,6‐diphenyl‐4(1H)‐pyridinone 3d,e derivatives, respectively. In addition, while prolonged reaction of n‐pentylamine with unsymmetrical pyrone derivative 1a gives a symmetrical pyridinone derivative namely 3,5‐dibenzoyl‐2,6‐dimethyl‐1‐pentyl‐4(1H)‐pyridinone 5, much prolonged action n‐pentylamine and then aqueous n‐pentylamine on 1b resulted in degradation of the 4‐pyrone ring to give dibenzoylmethane.
Synthesis of 5‐[(4‐phenylpiperazin‐1‐yl)methyl]pyrrolo‐[2,3‐d]pyrimidine derivatives as potential dopamine D4 receptor ligands
Authors: Linz Sabine , Troschütz Reinhard 
Published: March 2009

Abstractmagnified imageA series of pyrrolo[2,3‐d]pyrimidine Mannich bases of type 9, 12, 15 and 16 have been prepared as potential dopamine D4 receptor ligands. The syntheses start from 4‐aminopyrimidin‐6‐one 3 with pyrrole annulations and Mannich reactions with formaldehyde and phenylpiperazines 8 as new amine components.
Synthesis of new terpolymers with heterocyclic pendant groups
Authors: Vega Isabel N. , Sánchez Leonardo , D'Accorso Norma B. 
Published: March 2009

Abstractmagnified imageChemical modifications of polyacrylonitrile (PAN), an inexpensive and commercial homopolymer, to obtain terpolymers containing 1,2,4 or 1,3,4 oxadiazolic pendant groups are described. These new materials are physically and spectroscopically characterized.
A new series of non‐classical type C heteropentalenes: 2H‐pyrrolo[2,1‐c][1,2,4]triazoles
Authors: Moderhack Dietrich , Schneider Jan‐Christoph 
Published: March 2009

Abstractmagnified image7‐Functionalized title compounds 5 are obtained by cyclization of 3‐acetonyl‐ or 3‐[(alkoxycarbonyl)‐methyl]‐4‐phenacyl‐1,2,4‐triazolium salts 2 having methyl at C(5) the process can be effected in an acetate buffer or by base, irrespective of the function at C(3). 5‐Unsubstituted salts 2 do not react unless the side chain at C(3) is an acetonyl group. Cyclization of 2 with acetic anhydride‐base gives rise to 5,7‐difunctionalized compounds 8; again methyl at C(5) of 2 is compulsory, but here the reaction can be extended to salts having an (alkoxycarbonyl)methyl group at C(4). Regarding defunctionalization, acetyl groups can be split from C(5) only, whereas ester functions are removable also from C(7). Title compounds devoid of acceptor groups (XIII) are unstable but can be trapped by electrophilic reagents (DMAD, acetic anhydride, and phenyl isocyanate) to give the derivatives 10 and 12. The 7‐functionalized products 5 are likewise susceptible to SE‐reactions. By comparison, all title compounds appear to be more reactive toward this kind of reagents than the isomeric 1H‐pyrrolotriazoles (13) including 2H‐pyrrolotetrazoles (III). This is consistent with B3LYP‐DFT calculations using appropriate models.
Synthesis of novel 3,4‐diaryl‐1H‐pyrroles
Authors: Shafiee Abbas , Kassaee Mohammad Z. , Bekhradnia Ahamad R. 
Published: March 2009

Abstractmagnified imageThe synthesis of a series of novel 3,4‐diaryl‐1H‐pyrroles and related arylalkenes from p‐bromo thiophenol, tosylmethyl isocyanide and commercially available materials is reported. Arylalkenes having electron‐withdrawing substituents gave higher yield of 3,4‐diaryl‐1H‐pyrroles.
Stability in solution of indolium heptamethine cyanines and related pH‐sensitive systems
Authors: Strekowski Lucjan , Lee Hyeran , Mason J. Christian , Say Martial , Patonay Gabor 
Published: March 2009

Abstractmagnified imageRelative stabilities of methanolic solutions of dyes that are potentially important for labeling of biological macromolecules with a visible‐red or near‐infrared fluorophore were evaluated in the presence of molecular oxygen under dark and light conditions.
An efficient and modified biginelli one‐pot synthesis of new isoxazole substitted 3,4‐dihydropyrimidin‐2(1H)‐ones and thiones catalyzed by VCl3
Authors: Rajanarendar E. , Ramesh P. , Mohan G. , Rao E. Kalyan 
Published: March 2009

Abstractmagnified imageAn efficient and modified Biginelli one‐pot synthesis of new‐isoxazole substituted 3,4‐dihydropyrimidin‐2(1H)‐ones and thiones from aromatic aldehydes, ketoamide and urea/thiourea in acetonitrile using VCl3 as the catalyst is described.
One‐pot synthesis of symmetrically disubstituted 3H‐phenoxazin‐3‐ones by selective oxidative condensation with LTA
Authors: Sridharan Vellaisamy , Dhanalakshmi Pandi , Muthusubramanian Shanmugam 
Published: March 2009

Abstractmagnified imageA one‐pot synthesis of some new 2,8‐disubstituted 3H‐phenoxazin‐3‐ones from 4‐substituted‐2‐aminophenols through a selective oxidative condensation by lead tetraacetate in acetic acid is described.
Synthesis, stereochemistry and adsorption studies of new spiranes and polyspiranes containing 1,2‐dithiolane units
Authors: Gropeanu Radu A. , Ţînţaş Mihaela L. , Pilon Catherine , Morin Mario , Breau Livain , Turdean Raluca , Grosu Ion 
Published: March 2009

Abstractmagnified imageThe synthesis and stereochemistry of a series of new cyclic disulfides containing (poly)spirane 1,2‐dithiolane units are reported. Also included is a study of the self‐assembled monolayers (SAMs) of these compounds on a gold surface. The characteristics of the resultant SAMs were determined by IR spectroscopy using molecular mechanics calculations.
Synthesis and spectral data of quinoline products obtained by reaction of N‐(4‐pyridinyliden)anilines and N‐benzylidenaniline with 2,2‐dimethoxypropane (kametani reaction)
Authors: Kouznetsov Vladimir V. , Meléndez Gómez Carlos M. , Urbina González Juan M. , Stashenko Elena E. , Bahsas Ali , Amaro‐Luis Juan 
Published: March 2009

Abstractmagnified imageA study on interaction between N‐(4‐pyridinyliden)anilines 1‐4 and 2,2‐dimethoxypropane under Kametani reaction conditions was realized. According to the GC‐MS analysis of crude reaction, besides the needed 4‐methyl‐2‐(4‐pyridinyl)quinolines 5‐8, three collateral products: secondary amines 9‐12, 4‐(2‐methylprop‐1‐enyl)quinolines 13‐16 and 4‐(2‐methoxy‐2‐methylpropyl)quinolines 17‐20 were formed. Unexpected quinolines 13‐16 as well the desired quinolines 5‐8 were isolated and fully characterized. In contrast, a condensation of N‐benzylidenaniline 21 with 2,2‐dimethoxypropane afforded a set of different quinoline products.