bluuebunny/crossref_metadata_2025_split huggingface dataset:
Dynamic assessment of the abatement effects of the low-carbon practices in the prefabricated building supply chain
Authors: Du Qiang , Zhang Yerong , Zeng Lingyuan , Ma Yiming , Li Shasha 
Published: April 2024

PurposePrefabricated buildings (PBs) have proven to effectively mitigate carbon emissions in the construction industry. Existing studies have analyzed the environmental performance of PBs considering the shift in construction methods, ignoring the emissions abatement effects of the low-carbon practices adopted by participants in the prefabricated building supply chain (PBSC). Thus, it is challenging to exploit the environmental advantages of PBs. To further reveal the carbon reduction potential of PBs and assist participants in making low-carbon practice strategy decisions, this paper constructs a system dynamics (SD) model to explore the performance of PBSC in low-carbon practices.Design/methodology/approachThis study adopts the SD approach to integrate the complex dynamic relationship between variables and explicitly considers the environmental and economic impacts of PBSC to explore the carbon emission reduction effects of low-carbon practices by enterprises under environmental policies from the supply chain perspective.FindingsResults show that with the advance of prefabrication level, the carbon emissions from production and transportation processes increase, and the total carbon emissions of PBSC show an upward trend. Low-carbon practices of rational transportation route planning and carbon-reduction energy investment can effectively reduce carbon emissions with negative economic impacts on transportation enterprises. The application of sustainable materials in low-carbon practices is both economically and environmentally friendly. In addition, carbon tax does not always promote the implementation of low-carbon practices, and the improvement of enterprises' environmental awareness can further strengthen the effect of low-carbon practices.Originality/valueThis study dynamically assesses the carbon reduction effects of low-carbon practices in PBSC, informing the low-carbon decision-making of participants in building construction projects and guiding the government to formulate environmental policies.
Ideals versus realities of learning poverty and human rights
Authors: Glenn Liyana Eliza , Hardaker Glenn 
Published: April 2024

PurposeThis paper will identify and further explore the ideals versus realities of learning poverty and the consequential effects on our moral obligations and responsibilities. The wealthy nations are now under further pressure to recognise and realise their moral obligations to enabling social justice in the context of access, and distribution, of vaccines for the poorer nations. Learning poverty has always been a feature of our global economic, and institutional order, and has become an increasingly important factor in achieving justice.Design/methodology/approachThe study focusses on a human rights approach to learning poverty and the ideals versus the realities of what we are beginning to see in the times of a global pandemic. The major challenges to justice is inherent to the recognition that wealthy nations continue to have a pivotal role in the reduction of poverty. The identified major challenges in the context of learning poverty are: “nation states and the global pandemic”, “international interactions and learning poverty” and “global institutions and learning inequalities”. In particular, the authors explore the concept of ideals versus realities through three “challenges”, which continues to challenge any semblance of justice in the current global vaccine distribution. Nation states and borders, international interactions and global institutions remain barriers in overcoming what is becoming a reality of learning poverty.FindingsThis paper seeks to look beyond the economics of vaccine trade and seek a way to accept a moral claim of justice for all. The authors consider how wealthy nations are active participants in the emergence of learning poverty for many nations.Originality/valueBy exploring the ideals versus realities of learning poverty, and human rights, the authors highlight some of the challenges, and wealthy nations moral obligations, through the emergence of a new dimensional indicator of poverty, learning poverty.
Ethical forethoughts on the use of artificial intelligence in medicine
Authors: ElHassan Bassem T. , Arabi Alya A. 
Published: April 2024

Purpose
The purpose of this paper is to illuminate the ethical concerns associated with the use of artificial intelligence (AI) in the medical sector and to provide solutions that allow deriving maximum benefits from this technology without compromising ethical principles.

Design/methodology/approach
This paper provides a comprehensive overview of AI in medicine, exploring its technical capabilities, practical applications, and ethical implications. Based on our expertise, we offer insights from both technical and practical perspectives.

Findings
The study identifies several advantages of AI in medicine, including its ability to improve diagnostic accuracy, enhance surgical outcomes, and optimize healthcare delivery. However, there are pending ethical issues such as algorithmic bias, lack of transparency, data privacy issues, and the potential for AI to deskill healthcare professionals and erode humanistic values in patient care. Therefore, it is important to address these issues as promptly as possible to make sure that we benefit from the AI’s implementation without causing any serious drawbacks.

Originality/value
This paper gains its value from the combined practical experience of Professor Elhassan gained through his practice at top hospitals worldwide, and the theoretical expertise of Dr. Arabi acquired from international institutes. The shared experiences of the authors provide valuable insights that are beneficial for raising awareness and guiding action in addressing the ethical concerns associated with the integration of artificial intelligence in medicine.
Student voice and participatory self-governance at a German democratic free school: a content analysis
Authors: Morrison Kristan Accles 
Published: April 2024

Purpose
This paper aims to illustrate, by means of a content analysis of 278 weekly School Meeting minutes, the ways in which student voice is actualized in one democratic free school in Germany.

Design/methodology/approach
This paper uses a qualitative content analysis methodology of 278 weekly School Meetings minutes.

Findings
This paper uses Fielding’s (2012) patterns of partnership typology to illustrate what counts as student voice and participation in a democratic free school.

Research limitations/implications
Limitations included being reliant on translations of German texts, some missing minutes from the entire set, the lack of a single author for the minutes (and thus degree of detail differs) and the fact that the School Meeting minutes make reference to other meetings for various sub-committees for which no minutes exist, and thus, findings on the degree of student voice may be limited. And because this is a study of one school, generalizability may be difficult. Future research into these sub-committee meetings would prove helpful as well as content analyses of other democratic free schools’ meeting minutes.

Originality/value
This study can help people more deeply understand what goes on in democratic free schools and what student voice and participation can mean within this context.
Climate change and corporate culture of innovation: evidence from earnings conference calls
Authors: Ongsakul Viput , Chintrakarn Pandej , Jiraporn Pornsit , Chatjuthamard Pattanaporn 
Published: April 2024

Purpose
Exploiting novel measures of climate change exposure and corporate culture generated by a powerful textual analysis of earnings conference calls, this study aims to explore the effect of firm-specific climate change exposure on corporate innovation through the lens of corporate culture.

Design/methodology/approach
The authors apply the standard regression analysis as well as a variety of sophisticated techniques, namely, propensity score matching, entropy balancing and an instrumental-variable analysis with multiple alternative instruments.

Findings
The authors find that more exposure to climate change risk results in more innovation, as indicated by a significantly stronger culture of innovation. The findings are consistent with the notion that firms more exposed to climate change risk are pressed to be more innovative to adapt to the numerous changes caused by climate change. Finally, the authors also find that the effect of firm-level exposure on innovation is considerably less pronounced during uncertain times.

Originality/value
The authors are among the first studies to take advantage of a novel measure of firm-specific exposure to climate change and investigate how climate change exposure influences an innovative culture. Since climate change is a timely issue, the findings offer important implication to several stakeholders, such as shareholders, executives and investors in general.
Uterine contractile activity and neonatal outcome – A blind analysis of a randomized controlled trial cohort
Authors: Juhantalo Milla , Hautakangas Tuija , Palomäki Outi , Uotila Jukka 
Published: April 2024

AbstractIntroductionSufficient contractions are necessary for a successful delivery but each contraction temporarily constricts the oxygenated blood flow to the fetus. Individual fetal or placental characteristics determine how the fetus can withstand this temporary low oxygen saturation. However, only a few studies have examined the impact of uterine activity on neonatal outcome and even less attention has been paid to parturients’ individual characteristics. Our objective was therefore to find out whether fetuses compromised by maternal or intrapartum risk factors are more vulnerable to excessive uterine activity.Material and methodsUterine contractile activity was assessed by intrauterine pressure catheters. Women (n = 625) with term singleton pregnancies and fetus in cephalic presentation were included in this secondary, blind analysis of a randomized controlled trial cohort. Intrauterine pressure as Montevideo units (MVU), contraction frequency/10 min and uterine baseline tone were calculated for 4 h prior to birth or the decision to perform cesarean section. Uterine activity in relation to umbilical artery pH linearly or ≤7.10 was used as the primary outcome. Need for operative delivery (either cesarean section or vacuum‐assisted delivery) due to fetal distress was analyzed as a secondary outcome. In addition, belonging to vulnerable subgroups with, for example, chorioamnionitis, hypertensive or diabetic disorders, maternal smoking or neonatal birthweight <10th percentile were investigated as additional risk factors.ResultsA linear decline in umbilical artery pH was seen with increasing intrauterine pressure in all deliveries (p < 0.001). Among parturients with suspected chorioamnionitis, every increasing 10 MVUs increased the likelihood of umbilical artery pH ≤7.10 (odds ratio [OR] 1.17, 95% confidence interval [CI] 1.02–1.34, p = 0.023). The need for operative delivery due to fetal distress was increased among all laboring women by every increasing 10 MVUs (OR 1.05, 95% CI 1.01–1.09, p = 0.015). This association with operative deliveries was further increased among parturients with hypertensive disorders (OR 1.23, 95% CI 1.05–1.43, p = 0.009) and among those with diabetic disorders (OR 1.13, 95% CI 1.04–1.28, p = 0.003).ConclusionsIncreasing intrauterine pressure impairs umbilical artery pH especially among parturients with suspected chorioamnionitis. Fetuses in pregnancies affected by chorioamnionitis, hypertensive or diabetic disorders are more vulnerable to high intrauterine pressure.
Continuous flow local anesthetic wound infusion for post‐operative analgesia following kidney transplantation
Authors: Thakker Parth U. , Temple Davis M. , Minnick Caroline , Ponzi Dominick , Badlani Gopal , Hemal Ashok , Doares William , Webb Christopher , McCracken Emily , Orlando Giuseppe , Jay Colleen , Farney Alan , Stratta Robert J. 
Published: April 2024

AbstractBackgroundSome patients with end stage renal disease are or will become narcotic‐dependent. Chronic narcotic use is associated with increased graft loss and mortality following kidney transplantation. We aimed to compare the efficacy of continuous flow local anesthetic wound infusion pumps (CFLAP) with patient controlled analgesia pumps (PCA) in reducing inpatient narcotic consumption in patients undergoing kidney transplantation.Materials and MethodsIn this single‐center, retrospective analysis of patients undergoing kidney transplantation, we collected demographic and operative data, peri‐operative outcomes, complications, and inpatient oral morphine milligram equivalent (OME) consumption.ResultsFour hundred and ninety‐eight patients underwent kidney transplantation from 2020 to 2022. 296 (59%) historical control patients received a PCA for postoperative pain control and the next 202 (41%) patients received a CFLAP. Median age [53.5 vs. 56.0 years, p = .08] and BMI [29.5 vs. 28.9 kg/m2, p = .17] were similar. Total OME requirement was lower in the CFLAP group [2.5 vs. 34 mg, p < .001]. Wound‐related complications were higher in the CFLAP group [5.9% vs. 2.7%, p = .03]. Two (.9%) patients in the CFLAP group experienced cardiac arrhythmia due to local anesthetic toxicity and required lipid infusion.ConclusionsCompared to PCA, CFLAP provided a 93% reduction in OME consumption with a small increase in the wound‐related complication rate. The utility of local anesthetic pumps may also be applicable to patients undergoing any unilateral abdominal or pelvic incision.
A heart transplant center experience with basiliximab induction strategies: A double edged sword?
Authors: Holzhauser Luise , Norris Maxwell , Molina Maria , Chambers Susan , Sundaravel Swethika , Rashed Eman , Gala Ketan , Fallah Tara , Bittermann Therese , Reza Nosheen , Wang Teresa , Atluri Pavan , Goldberg Lee , McLean Rhondalyn , Peyster Eliot 
Published: April 2024

AbstractBackgroundThe use of induction immunosuppression for heart transplantation (HT) is debated given the uncertain benefit and potential risks of infection and malignancy.MethodsThis is a retrospective single‐center analysis of 475 consecutive HT recipients from 2003 to 2020 grouped by use of induction with basiliximab group (BG) and the no basiliximab group (NBG). Subgroup analysis by era compared pre‐2016 standard‐basiliximab (BX) induction and 2016–2020 with selective‐BX use as part of a calcineurin‐inhibitor‐sparing regimen.ResultsWhen adjusted for confounders (sex, age, PRA, eGFR), the BG was less likely to have acute cellular rejection (ACR) (OR.42, p < .001), but had more antibody mediated rejection (AMR) (OR 11.7, p < .001) and more cardiac allograft vasculopathy (CAV) (OR 3.8, p = .04). There was no difference between BG and NBG in the incidence of malignancies or infections. When stratified by era (pre‐2016 vs. 2016–2020), ACR remained less common in the BG than the NBG (36% vs. 50%, p = .045) groups, while AMR remained more common (9.7 vs. 0% p = .005). There was no significant difference in conditional survival comparing pre‐and post‐2016 NBG (HR 2.20 (95% CI.75–6.43); however, both pre‐2016 BG and post‐2016 BG have significantly higher mortality (HR 2.37 [95% CI 1.02–5.50) and HR 2.69 (95% CI 1.08–6.71), p = .045 and.03, respectively].ConclusionBasiliximab reduces the incidence of ACR but increases the risk of AMR, CAV, and may be associated with increased mortality. Mechanistic studies are needed to describe a potential T‐cell‐escape mechanism with enhanced humoral immunity.
Healthy Outcomes through Peer Educators: Feasibility of a peer support diabetes prevention programme for African‐American grandmother caregivers
Authors: Vivian Eva M. , Chewning Betty A. , Voils Corrine I. , Brown Roger L. 
Published: April 2024

AbstractAimTo assess the protocol feasibility and intervention acceptability of a community‐based, peer support diabetes prevention programme (DPP) for African‐American (AA) grandmother caregivers at risk for diabetes.Materials and MethodsGrandmother caregivers were randomized in a 2:1 ratio to DPP (active comparator) or DPP plus HOPE (Healthy Outcomes through Peer Educators; intervention). DPP + HOPE incorporated support from a peer educator who met with participants in person or by telephone every week during the 1‐year intervention. Outcomes included: (1) recruitment rates, outcome assessment, and participation adherence rates assessed quantitatively; and (2) acceptability of the programme assessed through end‐of‐programme focus groups.ResultsWe successfully consented and enrolled 78% (n = 35) of the 45 AA grandmothers screened for eligibility. Eighty percent of participants (aged 64.4 ± 5.7 years) were retained up to Week 48 (74% for DPP [n = 17] and 92% for DPP + HOPE [n = 11]). All grandmothers identified social support, neighbourhood safety, and access to grocery stores as influences on their health behaviours. At Month 12, the active comparator (DPP) group and the intervention group (DPP + HOPE) had a mean change in body weight from baseline of −3.5 ± 5.5 (−0.68, −6.29) kg and − 4.4 ± 5.7 (−0.59, −8.2) kg, respectively.ConclusionsThis viable study met the aim of educating and equipping AA grandmothers with the practical and sustained support needed to work toward better health for themselves and their grandchildren, who may be at risk for diabetes. The intervention was both feasible and acceptable to participating grandmothers and their organizations.
Objective movement asymmetry in horses is comparable between markerless technology and sensor‐based systems
Authors: Kallerud Anne S. , Marques‐Smith Patrick , Bendiksen Helle K. , Fjordbakk Cathrine T. 
Published: April 2024

AbstractBackgroundA markerless artificial intelligence (AI) system for lameness detection has recently become available but has not been extensively compared with commonly used inertial measurement unit (IMU) systems for detecting asymmetry under field conditions.ObjectiveComparison of classification of asymmetric limbs under field conditions and comparison of normalised asymmetry data using a markerless AI system (SleipAI; recorded on a tripod mounted iPhone 14pro [SL]); the Equinosis Q Lameness Locator (LL); the EquiMoves (EM); and subjective evaluation (SE).Study designDescriptive clinical study.MethodsStraight line trot data were collected from 52 client‐owned horses in regular training. Limbs were categorised as symmetric or asymmetric. Number of analysed strides were compared with Wilcoxon's each pairs test. Inter‐rater reliability in classification of asymmetric limbs was assessed with Light's Kappa. Bland Altman analysis of normalised asymmetry data was performed.ResultsData from 41 horses were included. Most horses showed mild asymmetry. The EM analysed significantly more strides than the other systems, both for forelimbs and for hindlimbs (53 ± 11 strides for both, respectively; p < 0.006). The LL analysed significantly more hindlimbs strides (45 ± 13) than the SL (27 ± 6; p < 0.001). Moderate inter‐rater agreement for asymmetry classification was found between systems (k = 0.59 forelimbs; 0.44 hindlimbs); agreement decreased when including the SE. For the normalised asymmetry data, the strongest agreement was found between the two IMU systems.Main limitationsHorses were assessed during straight‐line trot only.ConclusionsThe objective systems were comparable in classification of asymmetric limbs under field conditions when using defined asymmetry thresholds. Discrepancies stemmed largely from the imposed thresholds (i.e., systems largely identified same‐side asymmetry). Overall, the strongest agreement was found between LL and EM. The SL analysed significantly fewer hindlimb strides than the LL and EM which could represent a limitation of the Sleip AI.
CircROR1 upregulates CCNE1 expression to promote melanoma invasion and metastasis by recruiting KAT2A
Authors: Sun Litong , Bin Shizhen , Huang Chenghui , Wang Qi 
Published: April 2024

AbstractCircular RNAs (circRNAs) play important roles in cancer occurrence and progression. To explore and elucidate the clinical significance of specific circular RNA in melanoma and its potential molecular mechanism. CircROR1 expression in melanoma cells and tissues was confirmed by qRT–PCR and ISH. qRT–PCR and Western blotting were performed to measure the levels of CCNE1, KAT2A, MMP9 and TIMP2. MTT, Transwell and wound healing assays were performed to evaluate cell proliferation, invasion and metastasis. A xenograft mouse model was established to further verify the CircROR1/CCNE1 axis in vivo. RNA pull‐down and RIP assays were performed to detect the direct interaction KAT2A and CircROR1. A ChIP assay was used to investigate the enrichment of H3K9ac acetylation in the CCNE1 promoter. CircROR1 was significantly upregulated in metastatic melanoma cells and tissues, promoting proliferation, invasion and metastasis in vitro and tumour growth in vivo. CircROR1 overexpression increased CCNE1 and MMP9 protein expression and decreased TIMP2 protein expression. Functional rescue assays demonstrated that CircROR1 played a role in promoting malignant progression through CCNE1. CircROR1 specifically bound to the KAT2A protein without affecting its expression. CircROR1 overexpression increased the level of H3K9ac modification in the CCNE1 promoter region by recruiting KAT2A, thus upregulating CCNE1 expression. CircROR1 upregulates CCNE1 expression through KAT2A‐mediated histone acetylation. Our research confirms the critical role of CircROR1 in melanoma invasion and metastasis, and CircROR1 could serve as a potential therapeutic target for melanoma treatment.
Enablers or deterrent? Role of street level managers in use of creativity at the frontlines
Authors: Bashir Mohsin , Masood Ayesha 
Published: April 2024

AbstractUsing qualitative data from frontline police organizations in Punjab, Pakistan, this article investigates the role of street level management on creativity and improvisation in the frontline. Our findings show that the professional identities and attitudes of the street level managers play an important role in mediating creativity by the frontline workers, especially in the hierarchal organizational structure. If the managers adopted rule‐following attitude, frontline workers often faced hindrances in the use of creativity, leading to alienation. In contrast, if managers adopted a defiant attitude, frontline workers engaged in moderated creativity as they assumed the risk of rule breaking. This shows that creativity and innovation in organizations with no formal mandate to improvize is a messy and political process. Our study indicates the need to extend the research on policy innovation to hierarchal bureaucracies and organisational contexts where team work is not encouraged.
Traceability of Guizhou green tea production areas based on multi‐element characteristics combined with biochemical components
Authors: Huang Qing , Xia Haitian , Zhang Ticui , Li Sen , Wang Yuanhao , Yu Xiaofang , Zhao Huifang 
Published: April 2024

SummaryThe unique geographical environment of Guizhou has created the unique quality characteristics of green tea. To distinguish green tea from different regions in Guizhou, and provide a theoretical basis for origin traceability and quality evaluation for producers and consumers, this article analysed 12 mineral elements, 2 stable isotopes and 3 biochemical components in green tea samples from different regions in Guizhou, and combined with analysis of variance (ANOVA), principal component analysis (PCA), linear discriminant analysis (LDA) and orthogonal partial least squares discriminant analysis (OPLS–DA), the possibility of identifying and distinguishing the origin of green tea in Guizhou was studied. The results show that LDA has the highest discriminant accuracy, which can reach 93.3%. In addition, the data showed that Ca, Zn, Mn, Cr, Pb, As and caffeine were important variables to distinguish green tea samples from different regions of Guizhou.