bluuebunny/crossref_metadata_2025_split huggingface dataset:
The origin of the focal spike in musicogenic epilepsy
Authors: Shibata Nobuyoshi , Kubota Fumio , Kikuchi Senichiro 
Published: March 2024

ABSTRACT
To clarify the pathogenesis of a typical case of musicogenic epilepsy, we examined interictal spikes using the dipole tracing method (DTM). The patient was a 49‐year‐old, right‐handed Japanese man. He first experienced seizures at the age of 32 years; listening to his favorite piece of music frequently triggered them. His seizure type is partial (often complex, but sometimes simple). An interictal EEG examination revealed many focal spikes in F8 and T4. We estimated equivalent current dipoles (ECDs) using DTM. We performed one‐dipole analyses on the peaks of the spikes using an EEG analyzer with a three‐layer head model called the scalp‐skull‐brain (SSB) model. We analyzed the interictal EEG because there were no spikes during the seizure. The ECDs were located in the posterior transverse temporal gyrus. The characteristics in this patient not only bolstered arguments in favor of the role of the right temporal lobe in musicogenic epilepsy, but also showed that transverse temporal gyri, which are included in the auditory area, could play an important role in musicogenic epilepsy.

[Published with video sequences].
Fewer women receive tertiary care for epilepsy in Kerala State, India
Authors: Thomas Sanjeev V. , Deetha T.D. , Nair Prabhachandran , Sarma Sankara P. 
Published: March 2024

ABSTRACT

Purpose
The stigma attached to epilepsy often restricts early diagnosis and optimal care, particularly among the underprivileged. We aimed to ascertain any gender bias in the utilization of services for epilepsy in a tertiary and community care facility in Kerala State, India.

Methods
The R. Madhavan Nayar Center for Comprehensive Epilepsy Care (RMNC) is a leading tertiary care facility in South India. The District Mental Health Program (DMHP) is a community‐based care facility that provides medical consultation and anti‐epileptic drugs (AED) free of charge. We analyzed the sex ratio (SR) – number of women per one thousand men – of all registrations in these centers according to year of registration, age, religion, income, distance from domicile to the center, and religion.

Results

The SR in the RMNC (1976‐2004, n = 12354) was 729. At RMNC, age‐specific SR increased up to the 3
rd
decade (864), and progressively declined beyond 50 years. The SR was lower for those domiciliated at more than 200 km from the center when compared to others. The SR at the DMHP (1999‐2004, n = 221) was high (1125). The age‐specific SR at DMHP showed two peaks at 21‐30 years (1368) and 51‐60 years (2333).

Conclusion
Fewer women with epilepsy (particularly in lower socioeconomic groups) receive tertiary care in this state, in spite of a higher SR in the community (907 for epilepsy and 1058 for all population). The tertiary treatment gap is wider for women over 30 years (particularly over 50 years), when their longer life expectancy is also taken into consideration.
Combining advanced neuroimaging techniques in presurgical workup of non‐lesional intractable epilepsy
Authors: Brázdil Milan , Mikl Michal , Chlebus Pavel , Pažourková Marta , Novák Zdeněk , Chrastina Jan , Prášek Jiří , Bolčák Karol , Fojtíková Dagmar , Horký Jaroslav , Tomčík Jan , Lžičařová Eva , Rektor Ivan 
Published: March 2024

ABSTRACT

Purpose
The rationale for this case report is to assess the degree of congruency between the results of several advanced functional, metabolic, and structural neuroimaging techniques used in patients with MRI‐negative focal epilepsy.

Methods
We investigated the presurgical evaluation and postoperative outcome of a patient with intractable, extratemporal epilepsy. Because the habitual seizures in this patient could be easily induced, six, advanced, neurodiagnostic techniques were successively applied (SISCOM, ictal FDG‐PET, ictal fMRI, postictal diffusion‐weighted imaging, voxel‐based morphometry, and MRS imaging).

Results
The findings for the neuroimaging methods investigated, within the left central region, were fairly congruent. Subsequent, invasive EEG recordings revealed a seizure‐onset zone at the site where most of the neuroimaging had shown abnormal findings. The surgical removal of the epileptogenic zone, as defined by concordant neuroimaging and SEEG data, resulted in seizure‐free postoperative outcome. Histopathological findings revealed mild focal cortical dysplasia.

Conclusion
Great efforts should be made to combine most of the advanced neuroimaging methods in the preoperative assessment of non‐lesional epilepsy surgery candidates.
Vasovagal syncope misdiagnosed as epilepsy for 17 years: prime importance of clinical history
Authors: Spanaki Marianna V. , Garcia Patricia , Schuger Claudio D. , Smith Brien J. 
Published: March 2024

ABSTRACT
Distinguishing epilepsy from syncope often can be challenging. We report a case of a 20‐year‐old patient with presumed refractory epilepsy since the age of 3 years. Although the clinical suspicion of syncope was raised at the age of 9 years, key historic features were not identified, cardiac work‐up was not pursued and despite lack of electrographic evidence of epilepsy, he received anticonvulsant treatment. During his presurgical evaluation for “refractory epilepsy”, one typical event was captured that was associated with asystole and normal electroencephalogram. The diagnosis of vasodepressor syncope was made and anticonvulsant medication was discontinued. With this case report, we would like to emphasize the importance of a meticulous history and the need to perform continuous video electroencephalographic with simultaneous electrocardiographic recordings in the evaluation of paroxysmal events with atypical presentation.

[Published with video sequences]
Pilomotor seizures associated with sequential changes in magnetic resonance imaging
Authors: Masnou Pascal , Gagnepain Jean‐Paul , Fouad Amal , Ducreux Denis , Adams David 
Published: March 2024

ABSTRACT
Piloerection is rarely described in seizures. This symptom has been most frequently observed in patients with temporal lobe epilepsy and is rarely the principal clinical feature of seizures. No specific etiology of epilepsy associated with pilomotor seizures has been reported. We present the first case of a patient who experienced sudden and transitory epilepsy with pilomotor seizures occurring several times a day for months, and associated with sequential changes of the left hippocampus demonstrated by magnetic resonance imaging.

[Published with video sequences]
Epilepsy and mental retardation: genetic syndromes
Authors: Livet Marie‐Odile , Villeneuve Nathalie , Daquin Géraldine , Cournelle Marie‐Anne , Mancini Joselle , Moncla Anne 
Published: March 2024

ABSTRACT
The identification of an etiology in children and adults with mental deficiency is a major challenge and needs a comprehensive clinical approach and multidisciplinary collaborations. Some genetic syndromes with intellectual disability may also be associated with specific dysmorphic features, behavioural patterns or electro‐clinically recognizable epilepsy syndromes. Identifying the epilepsy syndrome may prove to be an important clue for the diagnosis of the associated genetic syndrome. Moreover, the implicated chromosomal regions may be useful targets when searching for epilepsy genes. We review and discuss available data on some genetic syndromes (Angelman syndrome, duplication of the 15q11‐q13 region, Wolf‐Hirschorn syndrome, ring chromosome 20, fragile X syndrome) also presenting specific epilepsy features.
Seizures, epilepsy and infectious diseases of the nervous system
Authors: Vespignani Hervé , Najjar A. Al , Kremer Stéphane , Maillard Louis 
Published: March 2024

ABSTRACT
The recent onset of partial epileptic seizures, secondary generalized partial seizures, or tonic‐clonic generalized seizures are often diagnostic indicators of central nervous system infections (meningitis, encephalitis, single or multiple abscesses, sub‐dural empyema). The occurrence of status epilepticus (SE) from an infection is a serious factor to be considered in therapeutic management. Brain CT‐scan or MRI examinations are used to establish its parasitic, mycotic, bacterial or viral etiology. These studies also serve to confirm or modify the clinical diagnosis and the topographical origin of the infection. Nevertheless normal morphological examinations do not rule out a recent infection as a causative factor in epileptic seizures. This is especially true for meningitis in all age groups but particularly in children. Indeed, epileptic seizure onset in patients with meningitis is an indication of the presence of a cerebral abscess. In the acute phase, antiepileptic treatments are the rule of thumb. Their indication in the follow up phase with the purpose of preventing further seizures will depend upon the nature of the infection and availability of access to antiinfectious treatments. The risk of subsequent epileptic seizures is most common in patients with encephalitis and cerebral abscesses. In cases of trauma, infections affecting the central nervous system increase the risk of posttraumatic epileptic seizures.
Frontal lobe epilepsy manifesting with seizures consisting of isolated vocalization
Authors: Rego Ricardo , Arnold Stephan , Noachtar Soheyl 
Published: March 2024

ABSTRACT

Vocalizations may occur in focal epileptic seizures, which typically arise from frontal and temporal regions. They are commonly associated with other motor phenomena such as automatisms, tonic posturing, or head version. We report on a patient whose seizures were documented by video‐EEG monitoring, but in whom the observable ictal semiology consisted solely of a brief, monotonous vocalization. Ictal EEGs showed left frontal seizure patterns. Isolated vocalizations can constitute an ictal epileptic event and may be the only observable clinical manifestation of a left frontal lobe epilepsy.
[Published with video sequences]
Benign childhood epilepsy with centro‐temporal spikes (BCECTS): early onset of seizures is associated with poorer response to initial treatment
Authors: You Su Jeong , Kim Deok‐Soo , Ko Tae‐Sung 
Published: March 2024

ABSTRACT

Aim
Benign childhood epilepsy with centro‐temporal spikes (BCECTS) is the most common idiopathic partial epilepsy in children. Treatment attitudes remain a controversial issue. We examine features that could suggest refractoriness at onset.

Methods
We retrospectively reviewed the medical records of 144 children with BCECTS diagnosed at the Division of Pediatric Neurology, Asan Medical Center, from March 1, 1995, to April 30, 2002 and treated with AEDs. The patients were subdivided into two groups according to the number of antiepileptic drugs used for effective seizure control.

Results

Of the 144 patients, 75 were male and 69 were female, with a mean age at seizure‐onset of 7.2 ± 2.3 years (range, 2.1‐14.3 years); 119 children were taking one antiepileptic drug (AED) (Group A), and 25 were taking more than one (Group B). There were no significant group differences in female‐to‐male ratio, prescribed AEDs, number of seizures before the start of treatment, interval between seizure‐onset and start of treatment, presence of secondarily generalized seizures, or presence of bilateral EEG abnormalities. The groups differed however, in mean age at seizure onset (7.6 ± 2.2 years
versus
5.1 ± 1.9 years, p < 0.05) and percentage of patients with seizure‐onset before 3 years (p < 0.05).

Conclusions
When treated with AEDs, children with BCECTS usually respond well. However, an earlier onset of seizures is associated with more frequent seizures and initial refractoriness to medical treatment.
Diet therapy in refractory pediatric epilepsy: increased efficacy and tolerability
Authors: Kang Hoon‐Chul , Kim Heung Dong 
Published: March 2024

ABSTRACT
Since the resurgence of the ketogenic diet (KD) in the mid 1990s, this diet has been used worldwide for the treatment of refractory pediatric epilepsy, including in Asian countries. However, the KD is not a convenient therapy, especially because the customary diets of Asian countries contain substantially less fat than traditional Western diets. In addition, there are various complications associated with the diet that should be considered. Unfortunately, no international protocols have been developed with the exceptions of the Johns Hopkins Hospital protocol adopted by a substantial number of hospitals. While the Hopkins protocol has been the basic model, several revisions of the initial protocol have been suggested. Changes to the applicable ages, seizure types, etiologies, the initiation of the diet, the ratio of constituents to reduce the fat content, the duration of the diet, and revised formulae, such as ketogenic milk or the all‐liquid KD, have attempted to extend the indications of the KD and increase its tolerability and palatability. Recently, less restrictive KDs, including a modified Atkins diet and low‐glycemic‐index treatment, have been clinically tested. Here, we review these approaches toward a safer and more convenient therapeutic diet for refractory pediatric epilepsy.
Анализ влияния климатических факторов на допустимые перетоки активной мощности в энергосистемах
Authors: Шепелев Александр Олегович 
Published: March 2024

Рассмотрены вопросы учета влияния внешних факторов (скорости и угла атаки ветра, солнечной радиации и др.) на допустимые перетоки активной мощности в контролируемых сечениях энергосистем. Работы, связанные с учётом климатических факторов, в основном посвящены вопросам уточнения потерь активной мощности и расчету установившегося режима. В настоящей работе затронуты вопросы недостаточности существующих подходов при определении допустимых перетоков активной мощности в энергосистемах. Основная цель представленного исследования заключена в анализе степени влияния климатических факторов на допустимые перетоки активной мощности. Использованы методы численного моделирования утяжелённых режимов энергосистем с учётом влияния климатических факторов на допустимые перетоки активной мощности. Моделирование проведено в различных программных комплексах, в том числе RastrWin3 и Mathcad (реализация метода внутренней температурной коррекции для расчёта допустимых перетоков активной мощности с учётом технических ограничений). Результаты численных экспериментов показали, что при наиболее худших условиях охлаждения наблюдается снижение величины допустимого перетока активной мощности в контролируемом сечении, с учётом технических ограничений, на величину от 4,8 до 18,7 % в зависимости от тестовой схемы. При значительных скоростях ветра (3 м/с) и различных углах атаки ветра ситуация кардинально меняется, и допустимый переток активной мощности увеличивается на величину от 17,4 до 42,4 % в зависимости от тестовой схемы. Проведённые расчёты показали, что при учёте климатических факторов значительно изменяется допустимый переток активной мощности в контролируемом сечении, что может привести к ошибкам в планировании электрических режимов энергосистем.
Análisis Crítico de la Masculinidad Agresiva y la Feminidad Protectora en Adolescentes y Jóvenes Adultos
Authors: Rubio-Guzmán Eva M. , Urra-Canales Miguel 
Published: March 2024

Las conductas agresivas en la población adolescente y joven son preocupantes. Las investigaciones muestran mayor tendencia a la violencia en los varones, pero también se ha explorado la incidencia de los roles de género en los distintos tipos de conductas violentas. El objetivo ha sido analizar las evidencias empíricas sobre la influencia de los roles de género medidos por el BSRI, en el comportamiento agresivo de adolescentes y jóvenes. Para ello se ha realizado una revisión sistemática según directrices PRISMA de los estudios empíricos encontrados en Academic Search, PsicInfo, ProQuest y Google Scholar, incluyendo 16 estudios. Los resultados no son del todo concluyentes: de una parte de los estudios analizados muestran una relación directa y positiva entre los comportamientos violentos, con el rol de género masculino, y el valor protector del rol femenino. Sin embargo, otra parte de las investigaciones contradicen estos resultados, encontrando en la alta feminidad y la androginia vínculos significativos con algunos tipos de conductas violentas. Es importante que nuevas investigaciones aborden este objeto de estudio.
Temporary Seismic Network in the Metropolitan Area of Rome (Italy): New Insight on an Urban Seismology Experiment
Authors: Vassallo Maurizio , Cultrera Giovanna , Esposito Alessandro , Mercuri Alessia , Bobbio Antonella , Di Giulio Giuseppe , Milana Giuliano , Bordoni Paola , Ciaccio Maria Grazia , Cara Fabrizio 
Published: March 2024

Abstract
This study presents data and preliminary analysis from a temporary seismic network (SPQR), which was deployed in the urban area of Rome (Italy) for three months in early 2021. The network was designed to investigate the city’s subsurface while evaluating the feasibility of a permanent urban seismic network, and consisted of 24 seismic stations. Despite significant anthropogenic noise, the SPQR network well recorded earthquake signals, revealing clear spatial variability referable to site effects. In addition, the network’s continuous recordings allowed the use of seismic noise and earthquake signals to derive spectral ratios at sites located in different geological and lithological settings. During the experiment, there were periods of activity restrictions imposed on citizens to limit the spread of COVID-19. Although the observed power spectral density levels at stations may not show visible noise reductions, they do cause variations in calculated spectral ratios across measurement sites. Finally, a statistical noise analysis was conducted on continuous seismic station data to evaluate their performance in terms of detection threshold for earthquakes. The results indicate that all network stations can effectively record earthquakes with a good signal-to-noise ratio (≥5 for P and S phases) in the magnitude range of 1.9–3.3 at distances of 10 km and 80 km, respectively. In addition, the network has the potential to record earthquakes of magnitude 4 up to 200 km, covering areas in Central Italy that are far from the city. This analysis shows that it is possible to establish urban observatories in noisy cities such as Rome, where hazard studies are of particular importance due to the high vulnerability (inherent fragility of its monumental heritage) and exposure.
КЛЮЧОВІ НАПРЯМКИ РОЗВИТКУ ПІДПРИЄМСТВ ТУРИСТИЧНОЇ ІНДУСТРІЇ В ПІСЛЯВОЄННИЙ ПЕРІОД
Authors: Толстова А. В. , Кича Б. М. 
Published: March 2024

В статті досліджено основні напрямки розвитку підприємств туристичної індустрії. Визначено основні причини і перешкоди розвитку туризму в Україні, як виїзного так і внутрішнього. в післявоєнний період доцільним є збільшення асортименту туристичних послуг за рахунок реконструкції історичних пам’яток та памяток архітектури, розвиток структури інформаційного забезпечення. У післявоєнний період доцільно розвивати підприємства туристичної індустрії у таких напрямках як освітній, бізнесовий, медичний, зелений, спортивно-оздоровчий, місцями бойових дій. Визначено, що дієвим інструментом, який дозволить підвищити якість національного туристичного продукту до рівня міжнародних та європейських стандартів, ураховуючи глобалізацію туристичного ринку є туристичний кластер.
СОЦІАЛЬНА ВІДПОВІДАЛЬНІСТЬ УКРАЇНСЬКОГО БІЗНЕСУ: СТАН ТА АКТУАЛЬНІ АКЦЕНТИ РОЗВИТКУ
Authors: Дикань О. В. , Компанієць В. В. , Бела О. O. 
Published: March 2024

В публікації на основі відповідних досліджень встановлено, що в мирні часи український бізнес (переважно великі підприємства), здійснював соціально відповідальну діяльність на мінімально необхідному рівні (базовому та нормативному). У мотивації такої діяльності головними були моральні міркування, а раціональна - стратегічна (довгострокова) перспектива соціальної відповідальності майже не усвідомлювалась. Під час війни український бізнес, навіть в скрутних умовах, зміг дотриматися мінімального рівня соціально відповідальної діяльності. Щоб вирішити складні питання, які стали перед українським соціумом під час війни, цього рівня недостатньо. У зв’язку з цим ми визначили актуальні напрями реалізації соціальної складової соціальної відповідальності українського бізнесу в скрутний воєнний (повоєнний) час.
Pengaruh Kinerja Keuangan Terhadap Market Share Perbankan Syariah di Indonesia
Authors: Melina Delvia , Etty Gurendrawati  , Diah Armeliza  
Published: March 2024

ABSTRAK
This study aims to analyze the effect of financial performance on the market share of Islamic banking in Indonesia. This study uses secondary data, namely the quarterly financial reports of Islamic commercial banks in 2019-2021. The sample was selected using a purposive sampling method and a total sample of 96 data was obtained from 8 Islamic Commercial Banks that met the criteria. The data analysis method used in this study is the panel data regression method. The results of this study prove that the Capital Adequacy Ratio (CAR) variable has a significant negative effect on market share due to the high CAR ratio because Islamic banks always try to keep their CAR in accordance with applicable regulations. The Variable Operating Costs and Operating Income (BOPO) has no effect on Market Share because the average BOPO in the study year of 90% does not reflect the efficiency of business activities so that customers also do not see BOPO as having an influence on banking business activities. And for Third Party Funds (DPK) and Non-Performing Financing (NPF) have a positive effect on Market Share.
ABSTRAK
Penelitian ini bertujuan untuk menganalisis pengaruh kinerja keuangan terhadap pangsa pasar perbankan syariah di Indonesia. Penelitian ini menggunakan data sekunder yaitu laporan keuangan triwulan bank umum syariah tahun 2019-2021. Sampel dipilih dengan menggunakan metode purposive sampling dan diperoleh total sampel sebanyak 96 data dari 8 Bank Umum Syariah yang memenuhi kriteria. Metode analisis data yang digunakan dalam penelitian ini adalah metode regresi data panel. Hasil penelitian ini membuktikan bahwa variabel Capital Adequacy Ratio (CAR) berpengaruh negatif signifikan terhadap pangsa pasar karena tingginya rasio CAR karena bank syariah selalu berusaha menjaga CAR-nya sesuai ketentuan yang berlaku. Variabel Biaya Operasional dan Pendapatan Operasional (BOPO) tidak berpengaruh terhadap Pangsa Pasar karena rata-rata BOPO pada tahun penelitian sebesar 90% tidak mencerminkan efisiensi kegiatan usaha sehingga nasabah juga tidak melihat BOPO berpengaruh terhadap bisnis perbankan kegiatan. Dan untuk Dana Pihak Ketiga (DPK) dan Non-Performing Financing (NPF) berpengaruh positif terhadap Market Share.