bluuebunny/crossref_metadata_2025_split huggingface dataset:
Giant cell tumor of bone at distal radius suffered more soft tissue recurrence and ultrasonography is effective to detect the soft tissue recurrence
Authors: Cui Lukuan , Sun Yang , Jin Tao , Fan Daoyang , Liu Weifeng 
Published: April 2024

Abstract
Background
Soft tissue recurrence of giant cell tumor of bone (GCTB) is rare. This study aims to provide its prevalence, recurrent locations, risk factors, effective detection methods and a modified classification for this recurrence.

Methods
Patients with soft tissue recurrence after primary surgery for GCTB were screened from January 2003 to December 2022. General data, recurrence frequency, types according to an original classification (type-I: peripheral ossification; type-II: central ossification; type-III: without ossification), a modified classification with more detailed subtypes (type I-1: ≤ 1/2 peripheral ossification; type I-2: ≥ 1/2 peripheral ossification; type II-1: ≤ 1/2 central ossification; type II-2: ≥ 1/2 central ossification; type III: without ossification), locations, detection methods such as ultrasonography, X-ray, CT or MRI, Musculoskeletal Tumor Society (MSTS) scores were recorded. Multivariate regression analysis was conducted to identify risk factors for recurrence frequency.

Results
A total of 558 recurrent cases were identified from 2009 patients with GCTB. Among them, 32 were soft tissue recurrence. The total recurrence rate was 27.78% (558/2009). Soft tissue recurrence rate was 5.73% among 558 recurrent cases, and 1.59% among 2009 GCTB patients, respectively. After excluding one patient lost to follow-up, 10 males and 21 females with the mean age of 28.52 ± 9.93 (16–57) years were included. The definitive diagnosis of all recurrences was confirmed by postoperative pathology. The interval from primary surgery to the first recurrence was 23.23 ± 26.12 (2–27) months. Eight recurrences occurred from primary GCTB located at distal radius, followed by distal femur (6 cases). Recurrence occurred twice in 12 patients and 3 times in 7 patients. Twenty-seven recurrences were firstly detected by ultrasonography, followed by CT or X-ray (10 cases in each). Types at the first recurrence were 5 cases in type-I, 8 in type-II and 18 in type-III. According to the modified classification, 3 patients in type I-1, 2 in type I-2, 1 in type II-1, 7 in type II-2, and 18 in type III. The mean MSTS score was 26.62 ± 4.21 (14—30). Neither Campanacci grade nor recurrence type, modified classification and other characters, were identified as risk factors.

Conclusions
Soft tissue recurrence of GCTB may recur for more than once and distal radius was the most common location of primary GCTB that would suffer a soft tissue recurrence. Ultrasonography was a useful method to detect the recurrence. Since no risk factors were discovered, a careful follow-up with ultrasonography was recommended.
Establishment and molecular characterization of HCB-541, a novel and aggressive human cutaneous squamous cell carcinoma cell line
Authors: Laus Ana Carolina , Gomes Izabela Natalia Faria , da Silva Aline Larissa Virginio , da Silva Luciane Sussuchi , Milan Mirella Baroni , AparecidaTeixeira Silvia , Martin Ana Carolina Baptista Moreno , do Nascimento Braga Pereira Letícia , de Carvalho Carlos Eduardo Barbosa , Crovador Camila Souza , de Paula Flávia Escremin , Nascimento Flávia Caroline , de Freitas Helder Teixeira , de Lima Vazquez Vinicius , Reis Rui Manuel , da Silva-Oliveira Renato José 
Published: April 2024

AbstractCutaneous squamous cell carcinoma (cSCC) is a common type of skin cancer that can result in significant morbidity, although it is usually well-managed and rarely metastasizes. However, the lack of commercially available cSCC cell lines hinders our understanding of this disease. This study aims to establish and characterize a new metastatic cSCC cell line derived from a Brazilian patient. A tumor biopsy was taken from a metastatic cSCC patient, immortalized, and named HCB-541 after several passages. The cytokeratin expression profile, karyotypic alterations, mutational analysis, mRNA and protein differential expression, tumorigenic capacity in xenograft models, and drug sensitivity were analyzed. The HCB-541 cell line showed a doubling time between 20 and 30 h and high tumorigenic capacity in the xenograft mouse model. The HCB-541 cell line showed hypodiploid and hypotetraploidy populations. We found pathogenic mutations in TP53 p.(Arg248Leu), HRAS (Gln61His) and TERT promoter (C228T) and high-level microsatellite instability (MSI-H) in both tumor and cell line. We observed 37 cancer-related genes differentially expressed when compared with HACAT control cells. The HCB-541 cells exhibited high phosphorylated levels of EGFR, AXL, Tie, FGFR, and ROR2, and high sensitivity to cisplatin, carboplatin, and EGFR inhibitors. Our study successfully established HCB-541, a new cSCC cell line that could be useful as a valuable biological model for understanding the biology and therapy of metastatic skin cancer.
Extreme Weather Disruptions and Emergency Preparedness Among Older Adults in Ohio: An Eight-County Assessment
Authors: Rao Smitha , Doherty Fiona C. , Traver Anthony , Sheldon Marisa , Sakulich Emma , Dabelko-Schoeny Holly 
Published: April 2024

AbstractThe disproportionate risks and impacts of climate change and extreme weather on older adults are increasingly evident. While especially true in disaster-prone areas, human-caused climate change introduces an element of uncertainty even in previously identified “safe” regions such as the Midwestern United States. Using a cumulative disadvantage and vulnerability-informed framework and descriptive statistics from multiple data sources, this article provides an overview of climate impacts, vulnerabilities, and county-level characteristics, focusing on older adults living in Central Ohio. A comparative multiple-case study methodology was used to triangulate regionally representative primary and secondary data sources to examine state and county-level measures of vulnerability, emergency preparedness, and disruptions caused by extreme weather among older adults across eight counties in Central Ohio. Seventy-eight percent of older adults in the sample reported being prepared for emergencies per Federal Emergency Management Agency guidelines. Older adults in Union County reported the highest rates of preparedness, while those in Fayette County reported the lowest. County-level rates of disruption of life activities by extreme weather ranged widely. Among the most rural in the region, Fayette County emerged as uniquely disadvantaged, with the lowest median income, the most vulnerable across multiple social vulnerability dimensions, and the most reported disruptions to life activities from extreme weather. County profiles offer a snapshot of existing vulnerabilities, socioeconomic conditions, special needs, preparedness, and current disruptions among older adults in the region and can inform resource mobilization across community and policy contexts.
Room acoustics of Mycelium Textiles: the Myx Sail at the Danish Design Museum
Authors: Dwan Albert , Edvard Nielsen Jonas , Wurm Jan 
Published: April 2024

Abstract
Taking the Myx Sail displayed at the Danish Design Museum as a case study, this article investigates the room acoustics of an architectural installation made of Mycelium Textiles. Mycelium Textiles represent a novel typology of mycelium-based composites (MBC). The Myx Sail absorbers are grown on a composition of different layers of plant fibres combining woven jute textile with hemp mat and loose wood wool substrate enhancing the mechanical and acoustic properties of the composite. Two complementary acoustic tests were conducted to measure the absorbing properties of the mycelium material and its effects on the acoustics of the exhibition hall. The results show that the sail acts effectively as an acoustic absorber especially in higher range of frequencies, reducing the reverberation time and improving speech intelligibility. The effect of the sail on the overall room acoustics is especially effective, if the sound source is placed directly underneath the sail. The results of a complementary survey amongst visitors on their subjective perception of comfort and well-being however indicate that the degree to which a grown surface (and by extension, a grown building) is perceived positively or negatively depends on the relationship the individual has with Nature.
Congregation leader and member discussions in a church-based family strengthening, mental health promotion, and HIV prevention trial: Intervention mechanisms in a randomized trial in rural Kenya
Authors: Rasmussen Justin M. , Johnson Savannah L. , Ochieng Yvonne , Jaguga Florence , Green Eric , Puffer Eve 
Published: April 2024

Abstract
Collaboration with African religious congregations can promote psychosocial well-being with greater accessibility. Effective collaboration requires studying congregations as unique intervention contexts. This study explored how an intervention in western Kenya fit within and altered congregational discussion patterns. We conducted a cluster-randomized trial of a church-based intervention to improve family relationships, mental health and sexual health. For each intervention topic covered, we describe baseline and post-intervention changes in church leaders’ beliefs and communication as well as discussion frequency between leaders and members and among members. Mixed-effects logistic regression assessed pre-post change in member-reported discussion frequency. At baseline, members and leaders reported already discussing family, parenting, and emotions frequently and sexuality and finances less frequently. Leaders generally felt they should discuss all topics but were less comfortable and knowledgeable about sexuality and finances than other topics. After the intervention, leader comfort and knowledge increased and discussion frequency increased for nearly all topics, especially those discussed less initially. Good fit between the desires and activities of church members and leaders suggests the potential for further collaboration, especially on mental health and family well-being. Increased discussion of sensitive topics underscores the potential of community-level interventions to affect social norms.
NEW PERSPECTIVES ON OLD MATTERS: A REVIEW OF ARCHAEOLOGICAL AND CHRONOMETRIC DATA FROM ABRIGO DO SOL (MATO GROSSO, BRAZIL)
Authors: Gilson Simon-Pierre , Bueno Lucas 
Published: April 2024

ABSTRACTBased on the study of the primary documentation related to the excavations carried out by Eurico Miller in the 1970s at Abrigo do Sol, Mato Grosso (Brazil), we propose a new reading of the stratigraphic and chronological information obtained from this rock shelter. Despite the apparent incongruity in the chrono-stratigraphic distribution of published dates, a detailed examination of the stratigraphy and field notes allowed us to identify a chronometric sequence with regular distribution between the Middle Holocene and the Late Pleistocene periods for the Abrigo do Sol site. We present here the original documents related to radiocarbon dating and their analysis. We finally show the implications of this study for understanding this site and the discussions related to the ancient settlements of the Amazon forest.
IMPROVING IONPLUS MICADAS PERFORMANCE WITH RECESSED GRAPHITE
Authors: Broek Taylor A B , Roberts Mark L 
Published: April 2024

ABSTRACTCathodes with recessed sample surfaces have several benefits in cesium sputter ion sources, including higher output, more efficient use of sample material, and improved focusing of the extracted ion beam. However, the Ionplus MICADAS uses cathodes with a graphite surface that is essentially flush with the sample holder. To evaluate the performance of recessed graphite with the MICADAS and determine the optimal surface depth, we tested four different depths, including the standard (flush) pressing method, 0.5 mm, 1.0 mm, and 1.5 mm. We found that recessed depths of 1.0 and 1.5 mm resulted in 20% higher ion beam current compared to the standard method under the same source conditions. The results are consistent with the beam produced from the recessed targets being more narrowly focused with a lower emittance, resulting in better transmission through the accelerator. Small graphite samples (200 µg C) with recessed surfaces produced higher currents for longer, leading to a 2–3× increase in sample ionization efficiency. Additionally, there was some evidence that isotopic ratio measurements of recessed samples were more stable over time. Overall, samples recessed to 1 mm depth offered numerous advantages over the standard pressing method and we have subsequently started pressing all MICADAS graphite using this approach.
Wagner’s ‘Bridal Chorus’ from Lohengrin and its Use as a Wedding March
Authors: RANGE MATTHIAS 
Published: April 2024

AbstractThe ‘Bridal Chorus’ of Wagner’s 1850 opera Lohengrin is one of the most recognizable pieces of music in the world. This article explores how it became so inextricably associated with wedding ceremonies – real ones, or on stage and in film. Furthered by its use at several British royal weddings the music was especially popular at wedding ceremonies in Britain and the USA. Notwithstanding that the chorus was usually performed in an instrumental arrangement, its attractiveness as wedding music was strengthened by various new English texts, its popular title of ‘Here comes the Bride’ deriving from a 1915 silent film. On a different level, this study contextualizes and evaluates the long-lasting criticism of the use of Wagner’s ‘Bridal Chorus’ at wedding ceremonies. Proportional to the decline in its actual use, this criticism has now mostly gone; yet, the ‘Bridal Chorus’ remains as the archetypical music to represent the arrival of the bride.
Which Information Do Politicians Pay Attention To? Evidence from a Field Experiment and Interviews
Authors: Senninger Roman , Seeberg Henrik B. 
Published: April 2024

AbstractPoliticians are exposed to a constant flow of information about societal problems. However, they have limited resources and need to prioritize. So, which information should they pay attention to? Previous research identifies four types of information that may matter: public concern about a problem, problem attention by rival parties, news stories about problems, and statistical problem indicators. We are the first to contrast the four types of information through a field experiment with more than 6,000 candidates and multiple elite interviews in Denmark. The candidates received an email invitation to access a specially tailored report that randomly highlighted one of the four types of information. Statistical indicators and public opinion were accessed the most (26.9 per cent and 26.5 per cent of candidates in the two conditions). Our results provide new and important evidence about the types of information politicians consider when addressing societal problems.
Geology, fluid inclusions and C−O−S−Pb isotopic compositions of the Chahmileh Pb-Zn deposit, Central Iran: Implications for ore genesis
Authors: Mehrabi Behzad , Chaghaneh Nafiseh , Tale Fazel Ebrahim , Corfu Fernando 
Published: April 2024

AbstractThe Chahmileh Pb–Zn deposit, located northwest of the Central Iran Zone, is a sediment-hosted Pb–Zn deposit in the ‘Yazd-Anarak Metallogenic Belt’. It is hosted in Middle Triassic carbonate rocks and is mainly controlled by NW-trending faults. The main ore minerals are galena and sphalerite with minor chalcopyrite, pyrite, and quartz, dolomite, along with minor calcite and baryte as gangue minerals. Cerussite, hemimorphite, wulfenite, mimetite, smithsonite, malachite and iron oxy-hydroxides are the main non-sulphide ore minerals. The main styles of mineralization are vein-veinlet, breccia, disseminated and replacement in association with silicification and dolomitization. Microthermometry of fluid inclusions in dolomite and quartz indicates that the ore precipitated from a warm to hot basin-derived saline fluid. Dolomite samples have δ13CVPDB and δ18OVSMOW values of −0.99 to +1.99‰ and +20.74 to +25.48‰, respectively, and are plotted in the marine carbonate rocks field. These isotopic values suggest that CO2 in the hydrothermal fluids mainly originated from marine carbonate rock. The δ34S values range from +6.3 to +8.2‰ for galena, +5.9 to +6.2‰ for sphalerite, +1.4 to +3.4‰ for chalcopyrite and +15.0 to +17.4‰ for bayite are compatible with a predominant thermochemical sulphate reduction process, and with sulphur sourced from Triassic seawater. Galena samples have a homogeneous Pb isotopic composition that is indicative of a continental crustal reservoir as the main source of lead and probably for the other ore metals. Based on geology, mineralogy, texture and fluid characteristics, the Chahmileh deposit is classified as a carbonate-hosted Mississippi Valley-type deposit.
People Like Us? How Mass Preferences Are Shaped by Economic Inequality and Racial Diversity
Authors: Wager Emily 
Published: April 2024

AbstractThe US has experienced runaway economic inequality since the 1970s, yet there is no strong public support for government efforts that serve to narrow the growing disparities between citizens. Why? I point to the role of rising racial diversity. I argue Americans believe in conditional equality, where they support equalizing policies as long as they perceive the beneficiaries as people like themselves. However, as the country grows more diverse, citizens are less likely to perceive those around them as people like themselves. Using time-series cross-sectional data of the American states, I demonstrate that as racial diversity increases, the likelihood the public will respond to increasing inequality by supporting bigger government declines. This study provides evidence for the mechanism usually implied but rarely tested by studies of diversity and policy: mass preferences.
Experimental Insights Into Fault Reactivation and Stability of Carrara Marble Across the Brittle–Ductile Transition
Authors: Niu Lu , Zhou Yongsheng , Shao Tongbin , Wang Lei , Xu Xiwei , Rybacki Erik 
Published: April 2024

AbstractLittle is known about the impact of pressure (P) and temperature (T) on faulting behavior and the transition to fault locking under high P–T conditions. Using a Paterson gas‐medium apparatus, triaxial compression experiments were conducted on Carrara marble (CM) samples containing a saw‐cut interface at ∼40° to the vertical axis at a constant axial strain rate of ∼1 × 10−5 s−1, P = 30–150 MPa and T = 20–600°C. Depending on the P–T conditions, we observed the complete spectrum of deformation behavior, including macroscopic (shear) failure, stable sliding, unstable stick‐slip, and bulk deformation with locked faults. Macroscopic failure and stable sliding were limited to P < 100 MPa and T = 20°C. In contrast, at P ≥ 100 MPa or T ≥ 500°C, faults were locked, and samples with bulk deformation experienced strain hardening at strains ≤8.8%. At T = 100–400°C and P ≤ 100 MPa, we observed unstable stick‐slip behavior, where both fault reactivation stress and subsequent stress drop increased with increasing pressure and temperature, associated with increasing matrix deformation and less fault slip. Microstructures indicate a mixture of microcracking, twinning and dislocation activity (e.g., kinking and undulatory extinction) that depends on P–T conditions and peak stress. The transition from slip to lock‐up with increasing pressure and temperature is induced by an enhanced contribution of crystal plastic deformation. Our results show that fault reactivation and stability in CM are significantly influenced by P–T conditions, probably limiting the nucleation of earthquakes to a depth of a few kilometers in calcite‐dominated faults.
Response of Onshore Oceanic Heat Supply to Yearly Changes in the Amundsen Sea Icescape (Antarctica)
Authors: St‐Laurent P. , Stammerjohn S. E. , Maksym T. 
Published: April 2024

AbstractThe heat transfer between the warm oceanic water and the floating portion of the Antarctic ice sheet (the ice shelves) occurs in a dynamic environment with year‐to‐year changes in the distribution of icebergs and fast‐ice (the “icescape”). Dramatic events such as the collapse of glacier tongues are apparent in satellite images but oceanographic observations are insufficient to capture the synoptic impact of such events on the supply of oceanic heat to ice shelves. This study uses a 3D numerical model and semi‐idealized experiments to examine whether the current high melting rates of ice shelves in the Amundsen Sea could be mitigated by certain icescape configurations. Specifically, the experiments quantify the impacts on oceanic heat supply of presence/absence of the Thwaites Glacier Tongue, Bear Ridge Iceberg Chain, tabular iceberg B22, and fast‐ice cover seaward of Pine Island Ice Shelf (PIS). The experiments reveal that future changes in the coastal icescape are unlikely to reverse the high ice shelf melting rates of the Amundsen Sea, and that icescape changes between 2011 and 2022 actually enhanced them slightly. Ice shelves such as Crosson and Thwaites are found to have multiple viable sources of oceanic heat whose relative importance may shift following icescape reconfigurations but the overall heat supply remains high. Similarly, the formation of a fast‐ice cover seaward of PIS slows down the cavity circulation (by 7%) but does not reduce its heat supply.
A Comparison of Auroral Oval Proxies With the Boundaries of the Auroral Electrojets
Authors: Walker Simon James , Laundal Karl Magnus , Reistad Jone Peter , Ohma Anders , Hatch Spencer Mark , Chisham Gareth , Decotte Margot 
Published: April 2024

AbstractThe boundaries of the auroral oval and auroral electrojets are an important source of information for understanding the coupling between the solar wind and the near‐earth plasma environment. Of these two types of boundaries the auroral electrojet boundaries have received comparatively little attention, and even less attention has been given to the connection between the two. Here we introduce a technique for estimating the electrojet boundaries, and other properties such as total current and peak current, from 1‐D latitudinal profiles of the eastward component of equivalent current sheet density. We apply this technique to a preexisting database of such currents along the 105° magnetic meridian, estimated using ground‐based magnetometers, producing a total of 11 years of 1‐min resolution electrojet boundaries during the period 2000–2020. Using statistics and conjunction events we compare our electrojet boundary data set with an existing electrojet boundary data set, based on Swarm satellite measurements, and auroral oval proxies based on particle precipitation and field‐aligned currents. This allows us to validate our data set and investigate the feasibility of an auroral oval proxy based on electrojet boundaries. Through this investigation we find the proton precipitation auroral oval is a closer match with the electrojet boundaries. However, the bimodal nature of the electrojet boundaries as we approach the noon and midnight discontinuities makes an average electrojet oval poorly defined. With this and the direct comparisons differing from the statistics, defining the proton auroral oval from electrojet boundaries across all local and universal times is challenging.