bluuebunny/crossref_metadata_2025_split huggingface dataset:
Research on textile Defect detection Algorithm for Deep Learning
Authors: Si Yachao , Gao Jiajie , Zhao Xingxuan 
Published: April 2024

Abstract
Textile defect detection is a crucial aspect of the textile industry. H owever, the detection accuracy is often low due to the small size of textile de fects and the influence of fabric texture background. To address these issues, we propose a textile defect detection algorithm based on YOLOv8.The reparameter ized structure was introduced to the original YOLOv8 to achieve hardware effici ency with the RepGhost module. The head section incorporates a new GD Mechanism and includes the Wasserstein Distance loss function.This method accurately ide ntifies the location and type of defects in textiles with high precision under complex backgrounds, meeting the needs of industrial textile production. We con ducted training and comparison experiments on different models using the AITEX public dataset and Roboflow open source dataset. We also designed ablation expe riments to verify the considerable improvement of each enhancement on the evalu ation index. The experimental results indicate that the detection accuracy of t he enhanced YOLOv8 model in the task of detecting textile defects has increased by 18.9% to 93.8% on the public dataset. The number of parameters has increase d by 10.94MB, and the FLOPs have increased from 8.2G to 11.3G. The improved alg orithm has significantly enhanced the accuracy. It can effectively handle large amounts of data and recognize defects even under complex backgrounds, meeting the fast, complex, and high-precision requirements of the textile industry.
An Interest-Aware Graph based Recommendation Model for Unveiling User Preferences
Authors: Brown Katherine , Wong Ethan , Dubois Gabriela , Matthew Lucas 
Published: April 2024

Abstract
The rise of the Internet has ushered in an era of unprecedented data proliferation, presenting users with a daunting information overload dilemma when navigating a vast array of choices. This phenomenon has underscored the need for effective recommendation systems to assist users in navigating this abundance of information. Indeed, recommender systems have emerged as indispensable technologies for diverse online platforms, tasked with predicting user engagement with various projects. Many recommendation algorithms based on graph neural networks predominantly rely on user and item ID information to extract features, overlooking valuable user-item features embedded in additional data such as review texts. Alternatively, some approaches utilize auxiliary information to augment network training, adding complexity to the process. While models like GCMC and those presented in literature attempt to aggregate synergistic signals at different rating levels separately, they still do not adequately address the discrepancies in user viewpoints when amalgamating signals from multiple levels. Building upon the aforementioned considerations, this paper introduces an interest-aware message passing recommendation model. The proposed model employs two distinct methods to partition the graph into subgraphs: one for partitioning users and another for partitioning items separately. Through high-order graph convolution operations conducted within these subgraphs, the model aims to learn node representations for users and items, leveraging both weak user-item relationships within subgraphs and weak item-item relationships between subgraphs, thereby enhancing the expression of users' interests and preferences.
Electronic medical record system user satisfaction and its implications for individual work performance: The case of a university teaching hospital in Rwanda
Authors: Uwamungu Evode , Marara Alpha Arsene , Munyaneza Emmanuel , Pinney Joel 
Published: April 2024

Abstract
Information system user satisfaction has been extensively documented as a key component and a surrogate of success and a determinant of individual and organizational performance. However, most related studies have focused on measuring user satisfaction and its impact through mathematical models, which might not exhaustively capture the issues affecting user satisfaction and performance. This study was conducted at the “Centre Hospitalier Universtaire de Kigali”, one of the two tertiary public and university teaching hospitals in Rwanda. This hospital has been implementing OpenClinic as an electronic medical record system since 2007, and few studies have focused on its evaluation. In addition, no study has focused on understanding the implications of user satisfaction for individuals’ work performance in this hospital. This study was cross-sectional mixed research using an explanatory embedded design. The data were collected from a convenient sample of OpenClinic users through questionnaires, which included closed- and open-ended questions, to capture both quantitative and qualitative data. The OpenClinic user satisfaction was high (91%), as was the proportion of users who perceived it as having a positive impact on their work performance (94%). The relationship between user satisfaction and perceived impact was statistically significant, and satisfied users were 20 times more likely to perceive that the impact was positive than unsatisfied users. Important concerns were expressed by users, and the main concerns were the poor functionality of the system due to unstable internet, the limited capacity for use and the scarcity of computers. Therefore, the implementation of the Electronic Medical Record system at the hospital has been successful, and user satisfaction has led to a perceived positive impact; however, further improvements are needed for optimal success. The inclusion of a qualitative component in future studies is recommended for a better understanding of IS success.
I need to see me on TV: Parasocial affirmations of sexual and gender identity development of LGBTQ+ mass media consumers
Authors: Lowe Don 
Published: April 2024

Abstract
This project presents a new cycle model of media usage by LGBTQ+ community members in the United States that reveals a purpose previously unnamed and undefined. While parasocial contact, parasocial interaction, and parasocial relationships have been present in the academic literature for quite some time (as early as 1956 when Horton and Wohl first wrote of the phenomenon), use of media to parasocially affirm one’s LGBTQ+ status is unique to this study. This study used qualitative methods to examine a specific mass media audience, LGBTQ+ individuals, and asked them, in one-on-one interviews, how they utilize mass media to assist with their sexual and gender identity development.
Arguably, the most important finding is that: instead of parasocial interactions or parasocial relationships participants reported parasocial affirmations. Parasocial affirmations are defined by this project as usage experiences of media characters/personalities that allow for visualization of self-acceptance. These affirming associations in turn create a need for additional experiences and the process starts again. The affirmations include information about successful negotiation of sexual and/or gender identity and therefore, affirming their own sexual and gender identity. Theoretical implications of this study include an extension of the parasocial interaction/relationship theory with the addition of parasocial
Geç Roma – Erken İmparatorluk Dönemi Onurlandırılmış Çıplak Hermes Tipleri: Yenilenen ve Yinelenen Romalılar
Authors: Cosar Guler Dogus 
Published: April 2024

Hellen dünyasında çıplaklık sembolik bir anlam taşımaktaydı. Çıplak erkek vücudu güzellik, gençlik, cesaret, savaşta güçlü, sporda yenilmez ve hızlı olmanın bir göstergesi olarak bilinmekteydi. Romalılar ise Cumhuriyet Dönemi’nden itibaren Romalı kıyafetleri olan toga ile betimlenmiş olsalar da Roma dışında bulunan eyaletlerde toga yerine Hellenler için bahsi geçen ya da bilinen “sembolik çıplaklık” içeren onur heykel tiplerinde tasvir edilmişlerdir. Bir Romalı için çıplaklık sıra dışıdır. Bu nedenle, Romalıların günlük hayatta belli bir kıyafet yönetmeliğine göre hareket ettiği bilinirken, kimi zaman hayattayken kimi zaman ölümlerinin ardından neden kendilerini çıplak gösteren onur heykellerini tercih ettiklerinin sorgulanması gerekmektedir. Bu sorgulama ve sorgu sonucu uzun bir değerlendirme kısmı ile birlikte makalede yapılmıştır. Bu değerlendirme, metinde mevcut daha önce yayımlanmış arkeolojik materyaller ile veya yayınlar aracılığıyla ele alınmıştır. Bunun nedeni bu makalede bilinen tipler üzerinden Roma’nın Hellenler ile çıplak tipteki erkek heykellerinin etkileşimini daha net görebilmek için yapılmıştır. Araştırma boyunca üç ayrı Hermes tipinde toplam yedi adet onur heykelleri kendi tipleri altında incelenmiştir. Hermes tipleri sırasıyla “Hermes Farnese”, “Hermes Richelieu” ve “Sandaletini Bağlayan Hermes” şeklinde ana başlıklar halinde araştırılmıştır.
Her onur heykeli, dahil edildiği grubun altında gerek farklılıklarıyla gerekse benzerlikleri ile birlikte ele alınmıştır. Çalışmanın amacı, Hellenlerden itibaren Roma’nın Geç Cumhuriyet Dönemine doğru giriş yapıldığında bu dönemden itibaren değişen erkek onur heykel tiplerini saptamak ve karşılaştırmasını yapmaktır. Hem incelenen heykel tiplerinin sınıflandırılması adına hem de tiplerin altında incelenen erkek onur heykellerinin daha kolay anlaşılabilmesi için de heykeller gruplandırılmıştır. Her tip kendi grubu altında kronolojik olarak araştırılmış ve tiplerin önemi, değişimiyle birlikte ele alınmıştır. Yalnız Romalılar için onur heykeli denildiğinde akıllara sadece çıplak heykeller gelmemelidir. Çıplak tipler haricinde, yarı çıplak, giyimli ve zırhlı onur heykelleri de mevcuttur ancak başlıkta ve metinde sadece bu tip üzerinden bir değerlendirmeye gidilmiştir. Bu çalışma bir derleme olup, geniş bir değerlendirme ile sonlandırılmıştır.
İstanbul’un Fethi’nin 500. Yıldönümü Kutlamaları ve Muğla Basınına Yansıması
Authors: Akça Bayram 
Published: April 2024

1453 yılında İstanbul’un Fatih Sultan Mehmet tarafından fethedilmesi Türk ve dünya tarihi için bir dönüm noktası olmuştur. Bu fetih II. Meşrutiyet’ten itibaren çeşitli şekillerde kutlanmaya başlanmıştır. Nitekim 1914 yılında İstanbul’un fethi ilk defa büyük bir törenle kutlanmıştır.
1939 yılına gelindiğinde Cumhurbaşkanı İsmet İnönü’nün talimatıyla 1953 yılında kutlanacak olan İstanbul’un fethinin 500. Yıldönümü için hazırlılar başlamıştır. Bu bağlamda 1941 yılında Milli Eğitim Bakanı Hasan Ali Yücel başkanlığında bir komisyon kurulmuştur. 1950 yılında ise Demokrat Parti’nin iktidara gelmesinden kısa bir süre önce Cumhuriyet Halk Partisi tarafından İstanbul’un fethinin 500.Yılı kutlamaları için “İstanbul’un Fethinin 500. Yılı ve Müteakip Fetih Yıllarını Kutlama Derneği” adıyla bir cemiyet kurulmuştur. Bu cemiyet maddi zorluklara rağmen Demokrat Parti döneminde de İstanbul’un 500. fetih yılı kutlama hazırlıklarına devam etmiştir.
29 Mayıs 1953 tarihinde İstanbul’da “İstanbul’un Fethinin 500. Yılı ve Müteakip Fetih Yıllarını Kutlama Derneği”, fethin 500. yılı nedeniyle on gün boyunca bilimsel, kültürel ve sanatsal birçok etkinlik düzenlenmiştir. Bu etkinliklere halk yoğun ilgi göstermiştir. Ancak bu törenlere Cumhurbaşkanı Celal Bayar ve Başbakan Adnan Menderes’in iştirak etmemesi dernek yönetimi ve halkta bir burukluğa neden olmuştur. Bu olayı dönemin basını da sert bir şekilde eleştirmiştir.
İstanbul’un 500. fetih yılı etkinlikleri İstanbul’da olduğu gibi Muğla İlinin Milas İlçesi’nde de yapılmıştır. Bu dönemde Muğla’da çıkan “Muğla’da Demokrat Yayla Gazetesi” hem İstanbul’da hem Muğla’da hem de yurtdışında fetihle ilgili yapılan tüm etkinlikleri okuyucusuna günü gününe aktarmıştır.
Nanoemulsions a Delivery System in the Making for Tumor Targeting
Therapeutics: Evaluation and Characterization to Meet Clinical Challenges
Authors: Shankar Ravi , Upadhyay Prabhat Kumar , Kumar Manish 
Published: April 2024

Abstract::
Cancer is a complex disease characterized by the uncontrolled and unregulated growth
of cells followed by invasion and proliferation from the site of origin to other sites of the body.
Conventional chemotherapy largely kills rapidly expanding and dividing cancer cells by impairing
DNA synthesis and mitosis. It is associated with various types of adverse effects ranging
from simple nausea and appetite loss to serious ones like bone marrow depression and compromised
immunity etc., due to their non-selectivity and inability to differentiate. The ideal feature
of a delivery system is delivering the drug to the target place to achieve the most therapeutic
impact while having the least toxicity. With the advent of novel drug delivery systems, it has
been easier to deliver the drug to the target site. Utilizing new techniques and technology makes
it a feasible approach to target cancer cells. Nanoemulsions are isotropic mixtures of transparent
or translucent oil globules dispersed in an aqueous phase that is kinetically stable and supported
by an interfacial coating of surfactant and co-surfactant molecules with droplet sizes in the nanometre
range. Nanoemulsions are the delivery system of choice in case of cancer because of
certain key attributes, including biodegradability, biocompatibility, large surface area nonimmunogenicity,
and release behavior control. At the same time, nanoemulsions have been engineered
for various reasons, including enhanced biological half-life, target-specific binding ability,
and imaging capability at different therapy levels by modifying the characteristics of
nanoemulsions. This review focuses on current cancer treatment challenges and the role of
nanoemulsions in treating cancer with their production methods, characterization methods, application,
and quality attributes, which would help them make it to the clinics where cancer
treatment is going on.
A Review of the Medicinal Value and Chemical Composition of Flavonoids from Pongamia Pinnata: Recent Work in Drug Advancement and Therapeutics
Authors: Satapathy Trilochan , Kumar Yogesh , Pandey Ravindra Kumar , Shukla Shiv Shankar , Bhardwaj Shiv Kumar , Gidwani Beena 
Published: April 2024

Abstract:
Traditional medicine in many countries, including those where Pongamia pinnata (L.)
Pierreis grown, uses the plant for a wide variety of purposes, including the treatment of piles, skin
problems, and wounds. The objective of the present study was to discuss the medicinal value and
chemical composition of flavonoids obtained from P. pinnata. All parts of the plant contain several
phytoconstituents responsible for biological activity. These compounds include numerous types of
flavonoid derivatives, such as flavones and flavans, as well as terpenes, steroids, and fatty acids. The
information required about the plant and advancement in therapeutics was gathered from Pubmed,
ScienceDirect and Cochrane Library. Many different types of biological activity, including antioxidant,
antibacterial, anti-inflammatory, and anti-diabetic properties, have been observed in plant products
from this species in pharmacological research. However, more research into the plant's phytochemical
profile and the complicated pharmacological effects is required. This is because our current
understanding of the plant's chemical ingredients and the methods by which they exhibit certain biological
activities is limited. Thus, information regarding active constituents is required to develop
novel therapeutics and additional research on the toxicity of the other chemicals identified from this
plant is necessary.
Immunoregulatory Effects of the Active Form of Vitamin D (Calcitriol),
Individually and in Combination with Curcumin, on Peripheral Blood
Mononuclear Cells (PBMCs) of Multiple Sclerosis (MS) Patients
Authors: Fasihi Mahdieh , Samimi-Badabi Mahsa , Robat-Jazi Behrouz , Bitarafan Sama , Moghadasi Abdorreza Naser , Mansouri Fatemeh , Yekaninejad Mir Saeed , Izad Maryam , Saboor-Yaraghi Ali Akbar 
Published: April 2024

Objectives:
Multiple sclerosis (MS) is a chronic autoimmune inflammatory disease affecting the central nervous system. Immune cell subsets, notably T helper (Th) 17 and Th1, exert important roles in MS pathogenesis. Whereas, Treg cells modulate the disease process. Calcitriol, the active form of vitamin D, and curcumin, a bioactive compound derived from turmeric, play immunomodulatory effects relevant to autoimmune disorders, including MS. The objective of this study is to investigate the effects of calcitriol and Curcumin on Peripheral blood mononuclear cells (PBMCs) of individuals with MS.

Methods:
PBMCs from twenty MS patients were isolated, cultured, and exposed to 0.004 μg/mL of calcitriol and 10 μg/mL of curcumin. The cells underwent treatment with singular or combined doses of these components to assess potential cumulative or synergistic immunomod-ulatory effects. Following treatment, the expression levels of genes and the cellular population of Treg, Th1 and Th17 were evaluated using Real-time PCR and flow cytometry.

Results:
Treatment with curcumin and calcitriol led to a significant reduction in the expression levels of inflammatory cytokines and transcription factors related to Th1 and Th17 cells, including IFN-γ, T-bet, IL-17, and RORC. Furthermore, the frequency of these cells decreased following treatment. Additionally, curcumin and calcitriol treatment resulted in a significant upregulation of the FOXP3 gene expression and an increase in the frequency of Treg cells.

Conclusion:
This study demonstrates that curcumin and calcitriol can effectively modulate the inflammatory processes intrinsic to MS by mitigating the expression of inflammatory cytokines by Th1 and Th17 cells while concurrently enhancing the regulatory role of Treg cells. Moreover, the combined treatment of curcumin and calcitriol did not yield superior outcomes compared to single-dosing strategies.
ANALISIS PENGGUNAAN GAMES EDUKASI BERBASIS ANDROID DALAM PEMBELAJARAN BIOLOGI SISWA SMA NEGERI 11 PEKANBARU
Authors: Amelia Natasya , Hajar Ibnu 
Published: April 2024

Tujuan dari penelitian ini adalah untuk mengetahui bahwa penggunaan games aplikasi berbasis android dalam pembelajaran biologi siswa SMA Negeri 11 Pekanbaru. Metode penelitian yang digunakan adalah penelitian deskriptif kuantitatif. Jenis data yang di gunakan data kuantitatif seperti angket. Sumber data primer di peroleh dari angket, sedangkan data skunder di peroleh dari jurnal. Penelitian ini di lakukan di SMA Negeri 11 Pekanbaru. Pada penelitian ini yang di amati adalah game berbasis android dalam pembelajaran biologi di sekolah. Untuk populasi dan sampel yang di gunakan yaitu seluruh siswa kelas X.1 dan X.2 SMA Negeri 11 Pekanbaru dengan menggunakan teknik sampel jenuh dan semua populasi dijadikan sampel. Teknik pengumpulan data yang di gunakan dalam penelitian ini adalah dengan menggunakan teknik kuisioner, dengan instrumen penelitian adalah angket yang di isi oleh siswa melalui google form. Angket yang digunakan untuk memperoleh data tentang pendapat siswa mengenai game berbasis android dalam pembelajaran Biologi di sekolah. Kemudian data akan di analisis secara deskriptif kuantitatif. Hasil penelitian analisis data menunjukkan pada kesimpulan bahwa keinginan penggunaan games edukasi dengan android pada kriteria sangat tinggi (86%), motivasi siswa menggunggunakan games edukasi dengan android pada kategori baik (62%), dampak penggunaan games edukasi dengan android pada kategori baik (65%). Berdasarkan hasil penelitian dapat disimpulkan penggunaan games edukasi dengan android dalam pembelajaran biologi di kelas X SMA Negeri 11 Pekanbaru tahun ajaran 2023-2024 pada kategori baik.Kata Kunci: Game edukasi, Android, Pembelajaran Biologi
Metabolic stress and stress-limiting mechanisms in bronchial asthma combined with type 2 diabetes mellitus
Authors: Skiba T. A. 
Published: April 2024

Objective: to study the indicators of lipid peroxidation and the antioxidant system in the blood and moisture condensate of exhaled air in patients with AD combined with type 2 diabetes, and in the blood of these patients — total metabolites of nitric oxide. Materials and methods: the study involved 215 patients with persistent BA of moderate severity aged (38.6±2.4) years, including 88 men (40.9%), 127 women (59.1%). Among the examined patients with BA there were 64 — group I, persons with BA combined with type 2 diabetes — 151 (group II). The parameters of the lipid peroxidation system (LPS) in the blood serum were studied: malondialdehyde (MDA), diene conjugates (DC), and the antioxidant system (AOS) according to the activity of catalase and superoxide dismutase (SOD), the amount of total metabolites of nitric oxide (NOx), in the condensate of exhaled air moisture (KEAM) was determined general oxidant (GOA) and antioxidant (AOA) activity. Results: in patients with BA combined with type 2 diabetes, an increase in the concentration of POL products in the blood was revealed: MDA was 2.6 times (p<0.05) compared with the control group and 1.3 times (p<0.05) compared with the indicator in patients with AD, DC, respectively, 2.0 times (p<0.05) compared with the control group and 1.2 times (p<0.05) compared with I group. The activity of the enzymes AOS catalase and SOD in patients with comorbidity of BA and type 2 diabetes was found to be lower than in patients of group I. In the KEAM of patients with comorbidity of BA and type 2 diabetes, a significant increase in OOA and a decrease in OAA were noted. The concentration of NOx in the blood serum of group II patients was 1.6 times higher than in the control group (p<0.05), but 1.4 times lower than in patients with AD without comorbidity with type 2 diabetes (p<0.05). The direction of the revealed correlations between the products of POL in blood serum and KEAM confirmed the systemic nature of metabolic changes in the body of patients with AD, and their strength in group II patients — the negative effect of comorbid type 2 diabetes on the greater severity of these metabolic changes. Conclusions: the resulting changes in the state of LPS and AOS in the blood and KEAM of patients with BA combined with type 2 diabetes can be characterized as systemic metabolic stress, both components of which: oxidative and nitrosive are supported by insufficient stress-limiting mechanisms — low activity of AOS enzymes and possible depletion of nitric oxide production, which should be reflected in the means of correcting metabolic disorders in patients with this comorbidity.