bluuebunny/crossref_metadata_2025_split huggingface dataset:
High-Performance All-Solid-State Lithium Metal Batteries Enabled by Ionic Covalent Organic Framework Composites
Authors: Huang Jun , Cheng Lei , Zhang Zhenyang , Li Chen , Bang Ki-Taek , Liem Albert , Luo Hang , Hu Chuan , Lee Young Moo , Lu Yingying , Wang Yanming , Kim Yoonseob 
Published: March 2024

Abstract

Ionic covalent organic frameworks (iCOFs) are crystalline materials with stable porous structures. They hold great potential for ion transport, particularly as solid-state electrolytes (SSEs) for all-solid-state Lithium metal batteries (ASSLMBs). However, achieving an ionic conductivity of over 10−3 S cm−1 at room temperature using pure-iCOF-based SSEs, even adding additives such as lithium salts, is challenging as the voids work as strong resistances. Thus, highly conductive iCOFs typically require quasi-solid-state configurations with organic solvents or plasticizers. In this study, we prepared composites comprising iCOFs and poly(ionic liquid) (PIL) to make all-solid-state iCOFs electrolytes with an exceptional ionic conductivity up to 1.50 × 10−3 S cm−1 and a high Li+ transference number of > 0.80 at room temperature. Combined experimental and computational studies showed that the co-coordination and competitive coordination mechanism established between the PIL, lithium bis(trifluoromethanesulfonyl)imide (LiTFSI) and iCOFs enabled rapid Li+ transport while restricting TFSI− movement. ASSLMB cells, made of composite SSEs and LiFePO4 composite cathode, demonstrated an initial discharge capacity of 141.5 mAh g−1 at 1 C and r.t., with an impressive capacity retention of 87% up to 800 cycles. Overall, this work presents a breakthrough approach for developing advanced SSEs for next-generation high-energy-density ASSLMBs.
Implementation Of Two Cross Two Switch To Implement Bitonic Sorting Circuit
Authors: Bhattacharjee Subhasree , Sarkar Soumyadip , Das Kunal , Sadhu Arindam , Sarkar Bikramjit 
Published: March 2024

Abstract
Reversible logic synthesis is becoming a significant research component for post-CMOS computing devices, particularly quantum computing. In this work we connect the reversible logic synthesis problem to sorting algorithms. Reversible logic has emerged as a promising technology in recent years, with applications in low power CMOS, quantum computing, nanotechnology, and optical computing. The classical gates AND, OR, and XOR are not reversible. This paper employs the control swap gate to implement a 2x2 switch. In multiprocessor system different computing operations are performed concurrently to get higher throughput. Sorting network can be used to tie up different parts of a large complex system efficiently with least amount of hardware to perform concurrent operations. A sorting network can be built using a multiple input and multiple output switching network. Following the implementation of the 2x2 switch, a bitonic sorting circuit is designed. The goal of developing a reversible sorting circuit is to reduce power consumption while maintaining reliable communication. The bitonic sorting circuit was successfully implemented, and the output was simulated in IBM qiskit. This presents efficient sorting circuit that can sort binary numbers in ascending/descending order.
Evaluation of vulnerable zones to water pollution in the lower Soummam alluvial aquifer, Bejaia, Algeria
Authors: Ouyahia Nadia , Saou Abdelhamid , Maza Mustapha , Bouchraki Faiza 
Published: March 2024

Abstract
Understanding the critical relationship between the Soummam River and its alluvial aquifer is crucial for the protection of this vital water resource. The approach is based on monitoring the spatial and temporal evolution of physico-chemical parameters and identifying their origin through correlation with the geology and piezometry of the alluvial aquifer; this will be achieved using differential gauging and hydrogeochemical tracing. This will provide valuable information for the management and protection of this precious water resource. The case study focuses on the alluvial aquifer of the lower Soummam Valley in Bejaia, Algeria, where a unique natural barrier upstream creates a close hydraulic relationship between the river and the aquifer. This allows for water exchange, which we investigated through two sampling campaigns (high and low water) at 32 water points (boreholes, wells and stations). By tracking the movement of special chemical tracers in both the Soummam River and the underlying alluvial aquifer, this study confirms a direct hydraulic connection between them. This means that water can flow from the river into the aquifer, highlighting the potential risk of water pollution. This has helped us to identify areas where pollution from the river could seep into the groundwater, threatening the drinking water supply.
Rejuvenation of water bodies with recycled water
Authors: Tyagi Radhey Shyam , Singh S. K. , Goyal P. K. 
Published: March 2024

Abstract

This study investigated the new routes of groundwater replenishment in water-constrained urban communities. Against the present water demand of 1,440 million gallons per day (MGD) in Delhi, 1,000 MGD including 140 MGD groundwater is being supplied. Additionally, residents, institutions and commercial occupants are illegally extracting 250 MGD. This groundwater extraction is enormous in comparison with the water injected into the ground through rain water harvesting, resulting in the tremendous depletion of the groundwater table. The aim of the study is to replenish groundwater with tertiary treated effluent available round the year. The study is conducted on one natural water body rejuvenated in the South and another artificial water body constructed in West Delhi with the objective of determining whether groundwater can be replenished with tertiary treated water with an improved quality, and whether it can be replicated elsewhere. The qualities of the groundwater and water tables were checked before and after rejuvenating the water bodies. The utilization of tertiary treated effluents has resulted in raising the groundwater tables from 5 to 7 m and improved the quality of the groundwater in the past 2 years. This practice can be replicated elsewhere as done in Brisbane (Australia) and Singapore.
In Silico Analysis of Natural Plant-Derived Cyclotides with Antifungal
Activity against Pathogenic Fungi
Authors: Sharma Akshita , Butool Bisma , Sahu Pallavi , Mishra Reema , Mohanty Aparajita 
Published: March 2024

Background:
Fungal infections in plants, animals, and humans are widespread across
the world. Limited classes of antifungal drugs to treat fungal infections and loss of drug efficacy
due to rapidly evolving fungal strains pose a challenge in the agriculture and health sectors.
Hence, the search for a new class of antifungal agents is imperative. Cyclotides are cyclic plant
peptides with multiple bioactivities, including antifungal activity. They have six conserved cysteine
residues forming three disulfide linkages (CI-CIV, CII-CV, CIII-CVI) that establish a Cyclic Cystine
Knot (CCK) structure, making them extremely resistant to chemical, enzymatic, and thermal
attacks.

Aim:
This in silico analysis of natural, plant-derived cyclotides aimed to assess the parameters
that can assist and hasten the process of selecting the cyclotides with potent antifungal activity and
prioritize them for in vivo/ in vitro experiments.

Objective:
The objective of this study was to conduct in silico studies to compare the physicochemical
parameters, sequence diversity, surface structures, and membrane-cyclotide interactions
of experimentally screened (from literature survey) potent (MIC ≤ 20 μM) and non-potent (MIC >
20 μM) cyclotides for antifungal activity.

Methodology:
Cyclotide sequences assessed for antifungal activity were retrieved from the
database (Cybase). Various online and offline tools were used for sequence-based studies, such as
physicochemical parameters, sequence diversity, and neighbor-joining trees. Structure-based
studies involving surface structure analysis and membrane-cyclotide interaction were also carried
out. All investigations were conducted in silico.

Result:
Physicochemical parameter values, viz. isoelectric point, net charge, and the number of
basic amino acids, were significantly higher in potent cyclotides compared to non-potent cyclotides.
The surface structure of potent cyclotides showed a larger hydrophobic patch with a higher
number of hydrophobic amino acids. Furthermore, the membrane-cyclotide interaction studies
of potent cyclotides revealed lower transfer free energy (ΔG transfer) and higher penetration depth
into fungal membranes, indicating higher binding stability and membrane-disruption ability.

Conclusion:
These in silico studies can be applied for rapidly identifying putatively potent antifungal
cyclotides for in vivo and in vitro experiments, which will ultimately be relevant in the agriculture
and pharmaceutical sectors.
Tetrandrine for Targeting Therapy Resistance in Cancer
Authors: Lima Ellen Nogueira , Lamichhane Santosh , K. C Pramod Bahadur , Ferreira Elisa Silva , Koul Sweaty , Koul Hari K. 
Published: March 2024

Abstract:
During the last five decades, there has been tremendous development in our understanding
of cancer biology and the development of new and novel therapeutics to target cancer. However,
despite these advances, cancer remains the second leading cause of death across the globe.
Most cancer deaths are attributed to the development of resistance to current therapies. There is an
urgent and unmet need to address cancer therapy resistance. Tetrandrine, a bis-benzyl iso-quinoline,
has shown a promising role as an anti-cancer agent. Recent work from our laboratory and
others suggests that tetrandrine and its derivatives could be an excellent adjuvant to the current
arsenal of anti-cancer drugs. Herein, we provide an overview of resistance mechanisms to current
therapeutics and review the existing literature on the anti-cancer effects of tetrandrine and its potential
use for overcoming therapy resistance in cancer.
In silico Evaluation of NO-Sartans against SARS-CoV-2
Authors: Omidkhah Negar , Hadizadeh Farzin , Ghodsi Razieh , Kesharwani Prashant , Sahebkar Amirhossein 
Published: March 2024

Introduction:
Numerous clinical trials are currently investigating the potential of nitric
oxide (NO) as an antiviral agent against coronaviruses, including SARS-CoV-2. Additionally,
some researchers have reported positive effects of certain Sartans against SARS-CoV-2.

Method:
Considering the impact of NO-Sartans on the cardiovascular system, we have compiled
information on the general structure, synthesis methods, and biological studies of synthesized NOSartans. In silico evaluation of all NO-Sartans and approved sartans against three key SARS-CoV-
-2 targets, namely Mpro (PDB ID: 6LU7), NSP16 (PDB ID: 6WKQ), and ACE-2 (PDB ID: 1R4L),
was performed using MOE.

Results:
Almost all NO-Sartans and approved sartans demonstrated promising results in inhibiting
these SARS-CoV-2 targets. Compound 36 (CLC-1280) showed the best docking scores against
the three evaluated targets and was further evaluated using molecular dynamics (MD) simulations.

Conclusion:
Based on our in silico studies, CLC-1280 (a Valsartan dinitrate) has the potential to
be considered as an inhibitor of the SARS-CoV-2 virus. However, further in vitro and in vivo evaluations are necessary for the drug development process.
Relationship between Dietary Diversity Score and Dietary Total Antioxidant Capacity with some Cardio-Metabolic Risk Factors and Pro-Oxidant-Antioxidant Balance in Overweight and Obese Postmenopausal Women
Authors: Mahdavi Aida Malek , Tofighi Zahra , Rafraf Maryam , Jafari-Koshki Tohid , Elhami Elham 
Published: March 2024

Background:
Considering the significance of relation between dietary diversity and dietary
antioxidants in the mechanism of obesity and related outcomes and due to limited studies in
postmenopausal women, the present research was designed to evaluate the relationship between
Dietary Diversity Score (DDS) and Dietary Total Antioxidant Capacity (DTAC) with some cardio-
metabolic risk factors and Pro-Oxidant-Antioxidant Balance (PAB) level in overweight and/or
obese postmenopausal women.

Methods:
The research participants comprised 128 overweight and/or obese postmenopausal women
aged 45-65 years attending the health centers. Anthropometric measures, e.g., weight, height,
waist and hip circumferences, were obtained. Serum lipid profile, glucose, and insulin were determined,
and the Homeostasis Model Insulin Resistance (HOMA-IR) was estimated. PAB was determined.
DDS and DTAC were determined using information from the Food Frequency Questionnaire
(FFQ).

Results:
Compared to those in the first tertile, there was no significant relationship between anthropometric
and biochemical data with DDS neither among participants in the second tertile nor the
third tertile (P>0.05). Furthermore, considerable negative relationships were only observed between
waist-to-hip ratio (P=0.035) and waist-to-height ratio (P=0.006) with DTAC among participants
in the second tertile compared with those in the first tertile. Also, insulin and HOMA-IR
were inversely related to DTAC among participants in the second tertile (both P<0.001) and the
third tertile (P=0.004 and P=0.009, respectively) compared to those in the first tertile. There was
a considerable negative relationship between PAB and DTAC (P=0.036) among participants in
the third tertile compared with those in the first tertile.

Conclusion:
DDS was not correlated with a lower risk of obesity, abdominal adiposity, and better
metabolic features. Furthermore, this study demonstrated that higher DTAC was correlated with
lower abdominal obesity, insulin, HOMA-IR, and PAB levels.
The Effectiveness of the Reading, Mindmapping, and Sharing (RMS) Learning Model in Improving Students' Learning Outcomes in Road and Bridge Construction
Authors: Aminah Siti , Suryadi Dady , Rahayu Sri 
Published: March 2024

Background: The principal aim of this study was to evaluate the impact of employing the Reading, Mind Mapping, and Sharing (RMS) learning strategy on student learning outcomes within a course focused on road and bridge construction. The motivation for c conducting this research arose from the observation that SMK Negeri 1 Sumedang students exhibited inferior performance compared to their KKM peers in the context of road and bridge construction.Methods: Furthermore, limited research has explored the implementation of student-centred educational models within this specific realm. To address these concerns comprehensively, researchers opted to utilize a quasi-experimental strategy encompassing a non-equivalent control design. Data collection involved gathering information before the implementation of intervention methods through pre-tests and subsequently following up with post-tests post-intervention.Result: A detailed analysis of the gathered data demonstrated clear discrepancies in learning outcomes between both experimental and control groups. Additionally, A notable discovery involved calculating normalized gain (N Gain) values for participants utilizing RMS model techniques. Such calculations indicated a moderate level of enhancement, as apparent through median value determinations yielding 0.553. Additionally, outcomes among exceptionally effective participants yielded impressive N gain percentages, standing at around 55.26 percent.Conclusion: Accordingly, it can be concluded without doubt that implementing teaching techniques based on RMS (Reading, Mind Mapping, and Sharing) principles hold substantial promise in enhancing student comprehension levels within road and bridge construction curriculums.
Family Involvement in the Care of Hospitalized Older Adults: Protocol for a Qualitative Evidence Synthesis
Authors: Vick Judith B , Golden Blair P , Cantrell Sarah , Harris-Gersten Melissa Louise , Selmanoff Mollie R , Hastings Susan Nicole , Oyesanya Tolu O , Goldstein Karen M , Van Houtven Courtney 
Published: March 2024

Background
Older adults are frequently hospitalized. Family involvement during these hospitalizations is incompletely characterized in the literature.

Objective
This study aimed to better understand how families are involved in the care of hospitalized older adults and develop a conceptual model describing the phenomenon of family involvement in the care of hospitalized older adults.

Methods
We describe the protocol of a qualitative evidence synthesis (QES), a systematic review of qualitative studies. We chose to focus on qualitative studies given the complexity and multifaceted nature of family involvement in care, a type of topic best understood through qualitative inquiry. The protocol describes our process of developing a research question and eligibility criteria for inclusion in our QES based on the SPIDER (Sample, Phenomenon of Interest, Design, Evaluation, and Research type) tool. It describes the development of our search strategy, which was used to search MEDLINE (via Ovid), Embase (via Elsevier), PsycINFO (via Ovid), and CINAHL Complete (via EBSCO). Title and abstract screening and full-text screening will occur sequentially. Purposive sampling may be used depending on the volume of studies identified as eligible for inclusion during our screening process. Descriptive data regarding included individual studies will be extracted and summarized in tables. The results from included studies will be synthesized using qualitative methods and used to develop a conceptual model. The conceptual model will be presented to community members via engagement panels for further refinement.

Results
As of September 2023, we have assembled a multidisciplinary team including physicians, nurses, health services researchers, a librarian, a social worker, and a health economist. We have finalized our search strategy and executed the search, yielding 8862 total citations. We are currently screening titles and abstracts and anticipate that full-text screening, data extraction, quality appraisal, and synthesis will be completed by summer of 2024. Conceptual model development will then take place with community engagement panels. We anticipate submitting our manuscript for publication in the fall of 2024.

Conclusions
This paper describes the protocol for a QES of family involvement in the care of hospitalized older adults. We will use identified themes to create a conceptual model to inform further intervention development and policy change.

Trial Registration
PROSPERO 465617; https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42023465617

International Registered Report Identifier (IRRID)
PRR1-10.2196/53255
Міжнародна участь ГО «Асоціація стоматологів України» у Світовому стоматологічному конгресі в Австралії
Authors: Skrypnyk I.L. 
Published: March 2024

Під егідою Всесвітньої федерації стоматологів з 24 по 27 вересня 2023 року в місті Сідней (Австралія) організовано й проведено Світовий стоматологічний конгрес, що зібрав понад 8000 представників стоматологічної галузі з 200 країн світу. Головне гасло Світового стоматологічного конгресу — «Освіта для професійної майстерності стоматологів». Українську делегацію на цьому форумі представляли президент ГО «Асоціація стоматологів України» професор Ірина Мазур і генеральний секретар цієї організації доцент Ірина Скрипник. У рамках конгресу відбувся Світовий парламент стоматологів, на якому було затверджено низку документів, важливих для практичної діяльності стоматологічної галузі.
La Audiencia de la Nueva Galicia durante sus primeras etapas. Retrato institucional
Authors: Enciso Contreras José 
Published: March 2024

La Audiencia de la Nueva Galicia era un tribunal de alzada con amplia jurisdicción para apelar asuntos civiles y criminales. En principio estaba integrada por oidores alcaldes mayores, pero el esfuerzo de la monarquía española por dotar de mayor alcance a las audiencias indianas modificó su carácter de audiencia subordinada, para tener la categoría de audiencia y chancillería. Su traslado a Guadalajara en 1560 la convirtió en la sede indiscutible de la actividad administrativa, judicial, eclesiástica y política del reino. El artículo enlista a los presidentes, oidores y fiscales de la Audiencia de la Nueva Galicia, de 1547 a 1861.
PENGELOLAAN ADMINISTRASI NILAI SISWA SEKOLAH BERBASIS WEB (STUDI KASUS : SMK ROUDLOTUL MUBTADIIN JEPARA)
Authors: Luthfi Abdullah , Meimaharani Rizkysari , Nurkamid Mukhamad 
Published: March 2024

SMK Roudlotul Mubtadiin Jepara merupakan salah satu sekolah menengah kejuruan yang berada di Kota Jepara. Dalam rangka meningkatkan kualitas pelayanan kepada siswa, sekolah ini membutuhkan sebuah sistem untuk mengelola data nilai siswa yang mampu mengakomodasi kebutuhan pengelolaan data nilai siswa secara efektif dan efisien. Oleh karena itu, penelitian ini bertujuan untuk membuat sebuah sistem untuk mengelola data nilai siswa dan data akademik dengan fitur berbasis web yang dapat membantu pengelolaan nilai siswa dan data akademik di SMK Roudlotul Mubtadiin Jepara. Penelitian ini menggunakan metode pengembangan sistem informasi yaitu metode waterfall. Tahapan pengembangan sistem meliputi analisis kebutuhan, perancangan sistem, implementasi, pengujian, dan pemeliharaan. Pengelolaan Administrasi Nilai Siswa Sekolah Berbasis Web (Studi Kasus : Smk Roudlotul Mubtadiin Jepara) ini dilengkapi dengan fitur berbasis web yang memungkinkan akses data nilai siswa secara online, seperti jadwal pelajaran, nilai siswa, dan informasi lainnya. Hasil pengujian menunjukkan bahwa sistem ini memudahkan pengelolaan data nilai siswa dan memberikan kemudahan akses informasi kepada siswa, orang tua, dan staf pengajar. Implementasi Pengelolaan Administrasi Nilai Siswa Sekolah Berbasis Web ini diharapkan dapat meningkatkan efisiensi dan efektivitas pengelolaan nilai siswa maupun data lain di SMK Roudlotul Mubtadiin Jepara.
Rasch Model Analysis of the Social Prejudice Scale
Authors: Fitria Nita , Faizal Nur , Irawan Edy , Nurdin Astoni , Rosidah Ainur 
Published: March 2024

The measurement of social prejudice requires valid and reliable instruments to produce objective data. Tests of validity and reliability with classical theory on the instrument were found to have many weaknesses that required in-depth analysis so that the data obtained were not biased. This study aims to analyze the social prejudice scale of students by using the Rasch model approach. 50 respondents were taken from students of Guidance and Counseling study program. The numbers of items on the scale of social prejudice were 25 items. Data was analyzed using WinstepS software. The method used in this analysis was Rasch modeling method. Based on the analysis of 25 statements developed, there were 23 items that meet the standards that while the other items did not meet the standards. The reliability value of the scale is 0.86 which means that it is in a good category. The overall scale of social prejudice developed can be used to measure a student’s level of social prejudice.