bluuebunny/crossref_metadata_2025_split huggingface dataset:
Hepatitis Screening in Community Pharmacies as a Measure of Reducing the Rate of Infections
Authors: Dave Pallav 
Published: March 2024

The burden of dealing with HBV and HCV still remain despite the progress that has been made in screening, vaccination, and treating the infections. On average, there about 354 million cases of hepatitis globally. Hepatitis has high mortality rates. On average, 1.1 million people lose their lives to the infections each year. Addressing hepatitis requires rigorous measures one of them being increasing screening. Hepatitis infections are identified through screening. As such, screening and taking the right preventative and treatment measures can help to reduce the risk of infections. However, screening is still a challenge. The number of people who screen for hepatitis remains low despite the efforts that have been put in place to increase uptake. The uptake of screening is low because of inadequate access to screening centers. Thus, increasing screening settings can help to increase uptake. Community pharmacies can help to bridge this barrier by making screening more accessible. They are accessible and in close proximity to vulnerable populations, which makes them ideal as screening settings. This review explores the potential of community pharmacies as screening settings for HBV and HCV and whether they can help to reduce the rate of infections.
Keywords: screening, hepatitis B, hepatitis C, community pharmacies
The Role of the Audit Room in Auditor Development: Remote Work Experiences of Junior Auditors during the COVID-19 Pandemic
Authors: Tighe Alexander 
Published: March 2024

SUMMARY
This study examines the work experiences of junior auditors during the COVID-19 pandemic (“the pandemic”). In response to the pandemic, audit firms closed offices and conducted audits in remote work environments. I used semistructured interviews to gather qualitative data about the experiences of junior auditors during the pandemic. The evidence collected suggests that the loss of the audit room (i.e., a physical space for audit teams to collaborate) during the pandemic increased challenges for junior auditors in developing technical knowledge, socializing within the firm, and separating personal and professional lives. These challenges increased the difficulty of forming a professional identity as an auditor. My data suggest that the audit room serves as a classroom, social hub, and a physical barrier between work and life. My study extends research on auditor development and provides insights into how the pandemic and remote work arrangements impacted junior auditors and professionals in general.
Medicinal Mushrooms Cordyceps as a New Source of Bioactive Compounds and Their Complexation With Silver Ions
Authors: Uhrinová Anna , Maľučká Lucia Ungvarská 
Published: March 2024

Abstract
Mushrooms from the genus Cordyceps are characterized by a wide range of biological effects due to the diverse amount of substances contained in them and are an important source of bioactive compounds. In China, mushrooms of the genus Cordyceps have been used as a medicinal preparation of traditional Chinese medicine for centuries. So far, a considerable number of studies have been conducted that focused on analyzing the effects of Cordyceps, which include their antioxidant, antibacterial, immunomodulatory, antidiabetic, antitumor, and many other effects. The ability of fungi to form complexes with various metals is also interesting. It is believed that polysaccharides are the main component of the extracts involved in the complexation with metals, after which their biological effects are improved and deepened. The work deals with the comparison of the antioxidant and antibacterial effects of Cordyceps extracts with extracts of this mushroom enriched with silver ions. Based on scientific studies, it is assumed that there is a complexation between the chemical compounds of the extracts and silver.
Aminopeptidase N as a potential drug target
Authors: Farsa Oldřich , Ballayová Veronika , Žáčková Radka , Zubáč Peter 
Published: March 2024

Abstract
Aminopeptidase N (APN) is a broad specificity zinc metallopeptidase with many functions that do not always depend on its enzymatic activity. Among others, it is involved in tumor angiogenesis and metastasizing and also serves as a cellular receptor of some coronaviruses. Some APN inhibitors, such as bestatin or tosedostat, were used or tested as anticancer drugs in the past. Within the past two decades, we have prepared several series of potential APN inhibitors. Some of them reached interesting values of inhibitory activity and were also successfully tested for antiproliferation activity in cancer cell lines. We also performed some QSAR studies with APN inhibitors prepared by us and other authors.
Characteristics of Trust in Personal Financial Planning*
Authors: Cull Michelle , Sloan Terry 
Published: March 2024

ABSTRACT
This Australian study utilises quantitative and qualitative research planning. Affective characteristics of trust were found to be essential to the client-adviser relationship. Increased legislation and specific behavioural and technical competencies of advisers were also found to build consumer trust in financial advice. The study’s results provide guidance to financial advisers with regards to the skills and factors that build and maintain trust with clients. This may lead some advisers to engage in additional training or education programs to improve specific skills, or to reconsider the way they interact with clients.
Can Stakeholders be Satisfied with Accountants’ Education to Act as Advisors to Self-Managed Superannuation Funds
Authors: Freudenberg Brett , Boccabella Dale 
Published: March 2024

ABSTRACT
This article investigates to what extent accountants are taught about self-managed superannuation funds (SMSF) in their Australian undergraduate accounting degrees and subsequent professional education programs. The article reports a survey of 138 academics teaching into Australian undergraduate accounting degrees. The results indicate that during their undergraduate accounting degrees, students are likely to be taught little about SMSFs. In a curriculum audit of their subsequent professional studies through professional bodies there is also minimal coverage of SMSFs. The evidence presented in this paper supports reforms to increase the educational requirements for accountants to give specialist advice in this area.
True Links: Precursory Lessons from Golf for Effective Financial Behaviour
Authors: Knutsen Julie Therese , Malin Mirela , West Tracey , Brimble Mark 
Published: March 2024

ABSTRACT
This article presents the results from a preliminary study which finds there are three psychological errors common to golf and financial behaviour which are the cause of unfavourable outcomes, namely overoptimism, overconfidence and emotional judgements. To manage these errors, this study finds the same strategies used to improve golfing decisions could carry over into our understanding of effective financial behaviour. Further, linking the research of effective golf play with effective financial behaviour leverages upon a worldwide interest which we argue has the potential to provide a range of analogies and visual clues for financial education and financial planning.
Pengaruh Iklan YouTube terhadap Brand Awareness
Authors: Gavrila Sherina , Sari Wulan Purnama 
Published: March 2024

In this day and age, technology and information are increasing, many new games have appeared that are of interest to Generation Z children. One of them is Tower OF Fantasy, an RPG genre game developed by a Chinese company called Hotta Studio. developed and published by Level Infinite. Even if many games have the same or similar genres, developers try to make their games available to the masses. Hotta Studio uses a communication strategy in the form of advertising. Hotta Studio uses YouTube advertising to increase brand awareness. The purpose of this study was to determine the impact of Tower of Fantasy YouTube advertising on brand awareness. This study used a quantitative method through a survey method using a survey as a data collection method. The results of data analysis using a simple linear regression test showed that the coefficient of determination was 0.475, which corresponds to YouTube Tower of Fantasy influence and brand awareness of 47.5%. Also, using a simple linear regression test, we can see that the value of the regression coefficient is 0.482, so it can be translated that for every 1 level of YouTube advertising costs, the value of brand awareness increases. about 0.482., which means that the direction of influence of X and Y is positive.
Di era sekarang ini teknologi dan informasi kian berkembang banyak bermunculan banyak game baru yang diminati oleh anak-anak gen z. Salah satunya adalah Tower OF Fantasy yang merupakan game bergenre action RPG yang dibuat oleh perusahaan asal China yaitu Hotta Studio dan dipublikasikan oleh Level Infinite. Walaupun banyak game memiliki genre yang sama atau serupa , para developer berusaha untuk memperkenalkan game hasil buatan mereka kepada publik. Hotta Studio menggunakan salah satu strategi komunikasi yaitu berupa iklan. Hotta Studio menggunakan iklan YouTube untuk meningkatkan brand awareness. Penelitian ini bertujuan untuk mengetahui pengaruh yang diberikan oleh iklan YouTube Tower of Fantasy terhadap brand awareness. Penelitian ini menggunakan metode kuantitatif melalui metode kuesioner menggunakan survei sebagai metode pengumpulan data. Hasil dari analisis data melalui uji regresi linear sederhana menunjukan hasil besarnya koefisien determinasi sebesar 0,475 yang menunjukan bahwa pengaruh variabel iklan YouTube Tower of Fantasy dan Brand Awareness adalah sebesar 47,5%. Melalui uji regresi linear sederhana juga dapat dilihat bahwa nilai koefisien regresi sebesar 0,482 maka dapat diterjemahkan untuk setiap kenaikan 1% biaya variabel iklan YouTube, skor kesadaran merek meningkat sebesar 0,482, yang dapat diartikan bahwa arah pengaruh X dan Y adalah positif.
IDENTIFIKASI DAN SEBARAN JENIS Cinnamomum sintoc BL DENGAN MENGGUNAKAN SISTEM INFORMASI GEOGRAFI (SIG) DI RESORT CILIMUS DAN MANDIRANCAN TAMAN NASIONAL GUNUNG CIREMAI
Authors: Ismail Agus Yadi , Kosasih Dede , Novitasari Dian 
Published: March 2024

Jenis Cinnamomum sintoc Blume merupakan salah satu vegetasi penghasil minyak atsiri pada batang dan daunnya. Dalam upaya konservasi C.sintoc, maka perlu dilakukan studi untuk mengetahui populasi dan sebaran sintok diTaman Nasional Gunung Ciremai.Penelitian ini dilakukan untuk memperoleh informasi mengenai populasi, sebaran, dan karakteristik habitat Cinnamomum sintoc di Resort Cilimus dan Resort Mandirancan Taman Nasional Gunung Ciremaisehingga proses kelangkaannya dapat dicegah dan pengembangan dapat dilakukan dalam upaya pembudidayaan tanaman ini. Penelitian dilaksanakan di Resort Cilimus dan Mandirancan Taman Nasional Gunung Ciremai Provinsi Jawa Barat yang terletak pada koordinat 108° 24' 20.3706" - 108° 28' 40.2486" Bujur Timur dan 6° 49' 30.9185"- 6° 54' 3.8434" Lintang Selatan dengan luas wilayah 3.171,035 hektar. Penelitian dimulai bulan Juni sampai dengan bulan Agustus 2016. Identifikasi morfologi dan sebaran C.sintoc menggunakan metode observasi dengan melakukan penelitian langsung ke lapangan yang dilakukan di Resort Cilimus dan Mandirancan dibatasi berdasarkan ketinggian dari 500-1200 mdpl.Hasil penelitian menunjukkan bahwa Sebaran Cinnamomum sintoc pada lokasi penelitian banyak ditemukan individu pada Resort Cilimus sedangkan untuk Resort Mandirancan cenderung mengelompok terutama pada ketinggian 700 mdpal dan 900 mdpal.selain itu Habitat di Resort Cilimus Cinnamomum sintoc ditemukan hanya pada ketinggian 500-1200 mdpal dengan rata-rata suhu 26.3oC dan kelembaban 78% dan Resort Mandirancan ditemukan hanya pada ketinggian 500-1100 mdpal dengan rata-rata suhu 27.3oC dan kelembaban 75.5%. Dan habitat Cinnamomum sintocditemukan pada Zona tropik dataran rendah (0-1000 Mdpal) dan Zona sub montan atau Hutan pegunungan rendah (1000-1500 Mdpal).Kata Kunci: Cinnamomum sintoc, habitat, morfologi, sebaran
Expected Spesolimab Plasma Exposure following Intravenous and Subcutaneous Dosing in Patients with Generalized Pustular Psoriasis
Authors: Hawkes Jason , Guercio Jason , Kurup Sree , Li Xiujiang , Lebwohl Mark 
Published: March 2024

Introduction: Generalized pustular psoriasis (GPP) is a chronic, potentially life-threatening inflammatory skin disease characterized by widespread flares of sterile pustules. Spesolimab is a first-in-class anti-interleukin-36 receptor monoclonal antibody approved to treat GPP flares in adults via intravenous (IV) infusion. The aim of this study was to simulate the plasma pharmacokinetics (PK) of IV versus subcutaneous (SC) doses of spesolimab to compare drug exposure profiles and support dosing strategies in patients with GPP.
Methods: A population PK model was developed using individual-level PK, anti-drug antibody, and covariate data from eighteen studies in which subjects were treated with IV or SC spesolimab.1 The resulting PK model was used to simulate concentration-time profiles following varying doses of IV and SC spesolimab. Peak plasma concentration (Cmax), time to peak plasma concentration (Tmax), and area under the curve (AUC) were summarized for each dose regimen.
Results: Simulated spesolimab exposures demonstrated that the Cmax and AUC of the single dose 900 mg IV infusion consistently exceeded that of various single doses of SC spesolimab tested. A SC dose greater than two-fold higher would be required to attain a Cmax comparable to that of spesolimab 900 mg IV. The difference in exposure between the two administration routes was most pronounced in the first 2 weeks after administration. Slow absorption is expected with SC injection, with Tmax attained at later time points after SC dosing compared to immediately following the 90-minute infusion for IV dosing. Results were the same when simulating a two-dose regimen administered one week apart.
Conclusions: PK simulations suggest that treatment with IV and SC spesolimab can result in differences in drug exposure in clinical practice. The immediate and high exposure of IV spesolimab compared with the lower exposure of SC spesolimab are supportive of IV dosing with spesolimab in acute GPP flare treatment vs SC dosing.
Utility of anticoagulation, pre-smearing and post-smearing hemolytic techniques on morphological assessment and reproducibility in fluid cytology
Authors: Agrawal Meetu , Lata Priya , Singh Mukul , Lal Mahesh Kumar , Gupta Bhoomika , Shamsunder Saritha , Rani Shilpi , Madan Neha Kawatra , Ahuja Sana , Ranga Sunil 
Published: March 2024

Objective:
Knowledge of proper collection, storage, preservation, and processing techniques is critical to ensuring proper handling and analysis of fluid cytology specimens. This study was conducted to determine the effect of anticoagulation, pre-smearing acetic acid treatment technique, and saline rehydration technique on morphological assessment, reproducibility, and reporting in fluid cytology.

Material and Methods:
The study was carried out in the cytopathology laboratory over 2 months (April–May 2022), where 100 effusion samples were analyzed. At least 20–40 mL of fluid was collected in heparinized and non-heparinized containers for each patient. Samples were processed in cytospin and stained with Giemsa and Papanicolaou stains. For 70 hemorrhagic specimens, an extra smear was prepared from the sediment and subjected to the saline rehydration technique as per the Indian Academy of Cytologists (IAC) guidelines. Seventy-three hemorrhagic specimens whose quantity received was more than 35 mL were subjected to the pre-smearing technique. These smears were evaluated for (a) the presence or absence of blue background/any other background staining, (b) cellularity, (c) cell morphology and (d) the presence/absence of microclots.

Results:
Heparinized samples showed no compromise in cellular morphology or cellularity although a blue background was observed in an occasional case. The pre-smearing technique had less background hemorrhage and preserved cell characteristics. The post-smearing saline rehydration technique did not compromise the cellularity but distorted morphology and showed background staining.

Conclusion:
The pre-smearing acetic acid treatment showed better-preserved cellularity and cytomorphology with the absence of background staining when compared to the post-smearing saline rehydration technique.
Knowledge and Risk Assessment of Hepatitis B Infection among Barbers and Beauty Salon Workers in Mwanza, Tanzania
Authors: Kilonzo Semvua , Jaka Hyasinta , Mapunda Sylvanus 
Published: March 2024

Background and Objective
Community-acquired hepatitis B virus (HBV) infection is increasing in developing countries. In Tanzania, there is an exponential increase in barbershops and beauty salons, which are potential sites of transmission of HBV. Occupational exposure rates and HBV vaccination rates among salon workers are unknown; their level of knowledge about infection prevention and control (IPC) is also unknown. This study aimed to evaluate the risk of infection and the knowledge of barbers and beauty salon workers about HBV transmission and prevention.

Methods
A cross-sectional study was conducted using a convenience sample of 200 barbers and beauty salon workers from 13 barber shops and 13 beauty salons in the urban district of Mwanza, Tanzania. Data were collected using a self-administered questionnaire, entered into EpiData version 3.1, and analyzed with Stata version 13. Categorical variables were expressed as frequencies, and association levels were compared using Fisher’s exact test.

Results
Fifty-four percent of the study participants were female, and the mean age was 25 (21.0–29.5) years. A total of 126 (63%) participants were aware of the existence of HBV infection, of which only 22% had general good knowledge of HBV transmission and prevention. Both HBV awareness (P < 0.001) and good knowledge of its transmission and prevention (P = 0.03) were positively associated with higher levels of education. Seventy-three (36.5%) participants reported a history of occupational injuries. Merely 27.8% of participants were familiar with the correct methods of decontamination beauty tools, and only 14.3% understood the correct procedures for post-exposure wound care. Vaccination coverage was low with only (2%) of barbers and beauty salon workers having received vaccines.

Conclusion and Implications for Translations
The frequent occupational injuries and inadequate vaccination among barbers and beauty salon workers amplify their risk of HBV infection. They also lack basic knowledge about HBV transmission and prevention, placing the clients they serve at high risk for infection. We recommend that training on HBV Infection Prevention and Control (IPC) should focus on this specific group, and the implementation of these measures should be closely monitored in barbershops and beauty salons. Moreover, this vulnerable group should be considered for a global vaccination program.
Peculiarities of depicting a landscape in a literary text using the example of Francis Scott Fitzgerald's novel “The Great Gatsby”
Authors: Мурадова А.К. , Газимаева Х.А. 
Published: March 2024

В настоящей работе рассматриваются особенности изображения пейзажа в художественном тексте на примере романа Фрэнсиса Скотта Фицджеральда «Великий Гэтсби». Данное литературное произведение, созданное в 20-е годы ХХ века, представляет собой уникальный образец, в котором пейзаж играет существенную роль в раскрытии образов персонажей и основной идеи произведения. В рамках исследования нами были проанализированы отрывки романа, где описываются пейзажи, а также процитированы наиболее яркие и выразительные фрагменты. Было выявлено, что описания природы используются автором для передачи настроения героев и подчеркивания различий между ними. Так, для главного героя Джея Гэтсби характерен восторг перед роскошными садами его усадьбы, тогда как Том Бьюкенен демонстрирует пренебрежение к окружающей среде. Проведенный анализ позволил сделать вывод о том, что Фицджеральд мастерски использует пейзажи для создания атмосферы произведения и раскрытия внутреннего мира персонажей посредством их взаимодействия с окружающей средой. Данный прием позволяет считать роман выдающимся образцом художественного описания пейзажа. Для более наглядной демонстрации изложенных выше положений приведем несколько выдержек непосредственно из романа Фицджеральда с дальнейшим их анализом.
This paper examines the features of the depiction of landscape in a literary text using the example of Francis Scott Fitzgerald's novel The Great Gatsby. This literary work, created in the 20s of the twentieth century, is a unique example in which the landscape plays a significant role in revealing the images of the characters and the main idea of the work. As part of the study, we analyzed excerpts from the novel where landscapes are described, and also quoted the most striking and expressive fragments. It was revealed that descriptions of nature are used by the author to convey the mood of the characters and emphasize the differences between them. Thus, the main character Jay Gatsby is characterized by admiration for the luxurious gardens of his estate, while Tom Buchanan demonstrates disdain for the environment. The analysis led to the conclusion that Fitzgerald masterfully uses landscapes to create the atmosphere of the work and reveal the inner world of the characters through their interaction with the environment. This technique allows us to consider the novel an outstanding example of an artistic description of a landscape. To demonstrate the above provisions more clearly, we present several excerpts directly from Fitzgerald’s novel with their further analysis.