bluuebunny/crossref_metadata_2025_split huggingface dataset:
Structure of somatic pathology in patients with rhonchopathy
Authors: Ryabova M. A. , Karpishchenko S. A. , Ulupov M. Yu. , Faizova A. R. , Zinchenko A. V. 
Published: April 2024

Snoring is a sound phenomenon that is often a symptom of more serious condition – OSAS (obstructive sleep apnea syndrome). All patients with complaints of nocturnal snoring, daytime sleepiness, breathing stops in sleep, in addition to the standard otorhinolaryngological examination at the initial consultation should be diagnosed using validated questionnaires, scales to determine the presence of risk of OSAS, according to the results of which a decision is made to consult a -somnologist with further additional examination.The objective of this work was to evaluate the clinical manifestations, concomitant pathology, and complications in patients at the initial visit to an otorhinolaryngologist complaining of the presence of the acoustic phenomenon of snoring.Methods and materials. 304 patients with the diagnosis of rhonchopathy were examined. The inclusion criterion was the presence of the acoustic phenomenon of snoring. All patients underwent computed tomography of the maxillofacial region using contrast technique of the soft palate before radiation diagnosis with the followed morphometry.Results. Analyzing the results of our sample, we come to a clear understanding that each case is very individual and needs a balanced interdisciplinary approach.Conclusions. When choosing the treatment method for rhonchopathy, it is necessary to take into account the patient’s somatic status, BMI, the presence of chronic tonsillitis and other concomitant diseases to choose the volume and method of surgical treatment
Current issues of delayed disability of patients after COVID-19
Authors: Belash V. A. , Bilichenko E. B. , Lamden Iu. A. 
Published: April 2024

Introduction. The pandemic of the new coronavirus infection COVID-19 has made significant changes in all spheres of modern human life. Understanding disability in patients post COVID-19 (CoronaVirus Disease - 19) allows to assess the need for physical rehabilitation.The objective was to determine the relationship between post-COVID syndrome and the development of delayed disability in patients who have been exposed to the COVID-19 as part of the assessment of the need for rehabilitation.Methods and materials. Using the method of standardized phone interview (14) three and twelve months post COVID-19, 855 patients were surveyed with an assessment of the level of rehabilitation needs at the time before COVID-19 (anamnestically), as well as three and twelve months after the disease, on the rehabilitation routing scale (RRS), mobility on the Rivermead scale and comparison of results with clinical data on the course of COVID-19.Results. Delayed disability was revealed in patients post COVID-19. The necessity of active examination and rehabilitation measures in patients who do not need proper rehabilitation is shown (RRS – 1).Conclusion. Post-COVID syndrome may be a predictor of the development of delayed disability in patients post COVID-19. The use of RRS in patients post COVID-19 is a reliable method necessary in the process of determining further routing after the disease.
STANDARDIZATION OF CLINICAL PHARMACIST FUNCTIONAL RESPONSIBILITIES IN HOSPITAL SETTING IN UKRAINE AND ABROAD
Authors: Zimenkovsky Andriy , Макух Х.І. , Sekh Myroslava , Zayats Marta 
Published: April 2024

Aim. Collection, analysis, and standardization of practical functions of a clinical pharmacist in national and foreign inpatient health care facilities, as well as identification of barriers during the integration of clinical pharmacy services in Ukraine.
Materials and Methods. The applied methods include a systematic approach, bibliographic, standardization, group method of expert evaluations, structural-logical, analytical-comparative, computer data processing, and modeling. The object of research: survey protocols of national clinical pharmacists (n=22); international standards of professional activity for clinical pharmacists (n=7); experience of implementing clinical pharmacy services abroad (n=7). Research subject: functional responsibilities of clinical pharmacists.
Results and Discussion. The results of the survey revealed that the practical functions of clinical pharmacists in national healthcare facilities extend far beyond the administration of antimicrobial agents as defined by legislation. They also encompass the practical implementation of 26 additional functions. An original standardization model was developed, which enabled the identification of 13 groups of professional functional responsibilities of national clinical pharmacists within the provision of clinical pharmacy services. It was established that the most common are 2 groups of functional responsibilities: managerial/strategic (20.2%) and related to control and monitoring (15.5%). Based on the analysis and evaluation of international professional standards and practices, 20 groups of functional responsibilities were identified, which are implemented through the realization of 160 different functions, ensuring a comprehensive range of clinical pharmacy services in hospital settings. The expansion of clinical pharmacy services in Ukraine is currently limited by several factors: the absence of appropriate legislative and regulatory acts that would facilitate the provision of full clinical and pharmaceutical care to patients; available resources; the level of professional training of specialists; the absence of national association and the lack of collaboration with international professional associations or societies in clinical pharmacy.
Conclusions. The developed model for standardizing the functions of clinical pharmacists in healthcare facilities has allowed systematic categorization of the main groups of functional responsibilities, enabling the provision of a full spectrum of clinical pharmacy services in hospital settings. Further integration of the clinical pharmacist into national health care, as an equal and integral member of a multidisciplinary team of specialists, is possible under the conditions of the creation of relevant legislative\regulatory acts and the development or optimization of national clinical pharmaceutical education at all levels.
New details on the volcanic and tectonic evolution of the Mesoarchaean Dominion Group with special reference to the Syferfontein Formation in the Ottosdal area (South Africa)
Authors: Paprika D.E. , Agangi A. , Hofmann A. , Ringdahl P. , Hartmann S. , Déri-Takács J. 
Published: April 2024

Abstract
The ca. 2.96 Ga Dominion Group (DG) preserves the first subaerial volcano-sedimentary succession on the Kaapvaal Craton. Based on field and core observations, this study provides revised stratigraphic logs and geological maps from the area around Ottosdal that refine the understanding of the stratigraphic and tectonic evolution of these ancient rocks.
Fluvial sandstone and conglomerate of the Rhenosterspruit Formation (RsF) were deposited on granite basement, followed by andesitic to basaltic volcanic rocks of the Rhenosterhoek Formation (RhF). These amygdaloidal andesitic to basaltic lava units show fragmentation around lava flows that may represent an indication of prevalent subaerial environment. However, local hyaloclastite and pillow lava units indicate periodic aqueous conditions. The Syferfontein Formation (SF) has the most extensive exposures in the Ottosdal area and represents the youngest volcanic unit of the DG. The porphyritic and spherulitic volcanic rocks tell a story of subaerial volcanism interspersed with periods of lacustrine deposition of sandstone and shale. The Witwatersrand Supergroup (WSG) overlies the DG along an angular unconformity.
Folding affected the succession of the DG, WSG and the Ventersdorp Supergroup (Rietgat Formation). This event is reflected in small-scale folds and mullion structures in the central part of the study area and by larger scale north-northwest–south-southeast-striking anticlines and synclines. Folding was accompanied by northwest-southeast-striking thrust faulting, either during or shortly after the formation of the Ventersdorp Supergroup. In the study area, post-Ventersdorp deformation is restricted to east-northeast–west-southwest-striking faults.
Impact of fibromyalgia severity on patients mood, sleep quality, and quality of life
Authors: Singh Ruchi , Rai Nirendra Kumar , Pathak Akash , Rai Jyotsana , Pakhare Abhijit , Kashyap Priyanka Vikas , Rozatkar Abhijit R. , Mishra Shweta , Mudda Sofia 
Published: April 2024

Objectives:
Fibromyalgia syndrome (FMS) is characterized by persistent widespread pain which greatly impacts the quality of life (QOL). Pain not only limits patients’ daily activities but also restricts their social activities further leading to depression, anxiety, and stress. The present cross-sectional study elucidated the association of sleep quality and mood with increasing symptom severity of fibromyalgia and its impact on the QOL of fibromyalgia patients.

Materials and Methods:
Hundred adult fibromyalgia patients diagnosed by the American College of Rheumatology 2010 criteria were evaluated for: sleep – using the Pittsburgh sleep quality index, QOL by SF-36, pain-visual analog scales (VASs) and global pain scale (GPS), mood-depression, anxiety, stress scale-21, somatic symptoms, anxiety and depression – by patients health questionnaire somatic, anxiety, and depressive symptom scales (PHQ-SADS), and FMS severity was evaluated using fibromyalgia impact questionnaire (FIQR).

Results:
The mean pain score was 6.80 ± 1.58 on VAS and 54.10 ± 14.33 on GPS. FIQR score was 50.62 ± 13.68, mean sleep quality was poor (9.30 ± 3.88), and depression, anxiety, and stress scores were increased (10.04 ± 4.59, 8.33 ± 4.48, and 10.75 ± 4.66). An increasing trend of depression, anxiety, stress, and somatoform symptoms was observed with an increase in the severity of FMS when patients were compared according to FMS severity scores. Sleep also deteriorated with increasing severity of FMS from 5.66 ± 1.92 in mild FMS to 12.0 ± 3.41 in highly severe FMS patients. The QOL too deteriorated in all the domains with increasing severity.

Conclusion:
With the increasing severity of fibromyalgia, not only does the pain increase but mood and sleep quality also deteriorate, which further impacts the QOL of FMS patients. Thus, comorbid mood derangements must also be screened and addressed for maximum benefit of the patients.
Sémiotique de la « Taille »
Authors: Granjon Émilie 
Published: April 2024

Qu’il soit tailleur de pierre ou buriniste, l’artiste alchimiste ou franc-maçon utilise une technicalité de la « taille » précise et singulière. En altérant, creusant et polissant la matière, il reproduit le geste sémiotique de la tradition ésotérique : séparer la matière pour laisser jaillir l’unité d’une œuvre. Du savoir-faire de l’artiste-philosophe dit « ésotérique », se dégage une double phénoménologie, celle de la « taille » et celle des sciences ésotériques, qui donne à voir et à penser la production d’œuvres alchimiques et maçonniques, gravées et/ ou taillées, comme un acte énonciatif du discours « ésotérique ». Dans le présent texte, nous nous pencherons exclusivement sur les modalités sémiotiques qui instaurent un lien entre la production du signe gravée et sa signification « ésotérique »
Hilbertova aritmetizace geometrie
Authors: Zeman Jan 
Published: April 2024

Tato práce se podrobně věnuje způsobu, jakým David Hilbert (1862–1943) pojal aritmetizaci geometrie v knize Grundlagen der Geometrie z roku 1899. Nejprve stručně představíme Hilbertovy předchůdce z téže doby, kteří buď po změnách v založení geometrie volali, nebo je již sami prostřednictvím axiomaticko-deduktivní metody zapracovali. Neopomeneme přitom, co dílu předcházelo v dřívějších Hilbertových přednáškách. Následně se pokusíme nastínit­ obsah prvních dvou kapitol knihy a vysvětlit dobové i věcné souvislosti, nutné k jejich pochopení. Představíme způsob implicitních definic základních pojmů a vztahů v axiomech, a dále Hilbertovo rozdělení axiomů do skupin, přičemž se zejména zaměříme na axiomy spojitosti v kontextu s otázkou o její bezespornosti. K tomu popíšeme konstrukci aritmetického modelu axiomů geometrie, který Hilbert pro důkaz bezespornosti používá. V závěru se pokusíme nastínit hlavní důvody, které Hilberta k napsání díla vedly, a některé klíčové důsledky jeho pojetí axiomatiky geometrie.
Je možné vyriešiť spor realizmu a konštruktivizmu?
Authors: Kostolný Rastislav 
Published: April 2024

Cieľom textu je nadviazať na diskusiu o spore realizmu a konštruktivizmu, ktorá prebehla medzi Jaroslavom Peregrinom a Tomášom Marvanom na stránkach časopisu Filosofie dnes. Samotná diskusia vznikla ako reakcia na Marvanom publikovanú knihu Realismus a relativismus. Marvan v nej zastáva špecifické stanovisko realizmu, z ktorého vedie kritiku relativizujúcich postojov. Peregrin tvrdí, že spor nie je možné riešiť, lebo obe súperiace strany sú v konečnom dôsledku nevyvrátiteľné a argumenty pre a proti sa držia v patovej situácii. Marvan tvrdí, že spor je možné riešiť v prospech realizmu. Predkladaný text sa voči obom názorom vymedzuje a predstavuje návrh ako daný spor riešiť. Riešenie spočíva v rozpustení samotného sporu a v predstavení hybridnej koncepcie, ktorá problémy realizmu a konštruktivizmu prekonáva. Text je rozdelený na tri časti, v prvej je uvedená kritika Marvanom zastávaného realizmu, v druhej časti je predstavená stručná analýza zdroju sporu a v záverečnej časti je načrtnutá koncepcia, ktorá spor prekonáva.
Filip Tvrdý o naturalizaci filosofie
Authors: Hříbek Tomáš 
Published: April 2024

Článek rozlišuje několik verzí současného naturalismu: revizionistickou, konstruktivní a antireprezentacionalistickou. Revizionistický naturalismus doporučuje nahradit tradiční filosofické zkoumání povahy věcí genetickým zkoumáním původu našich, často mylných, přesvědčení o povaze věcí. Konstruktivní naturalismus akceptuje zadání tradiční filosofie, ale doufá, že dokáže její otázky zodpovědět pomocí více méně vědeckých metod. Antireprezentacionalistický naturalismus je extenzí metaetického expresivismu v tom smyslu, že popírá deskriptivní povahu všech filosofických tezí. Tyto distinkce mohou pomoci klasifikovat jeden z nejexplicitněji naturalistických projektů v novější české filosofii, Nesnáze introspekce (2015) Filipa Tvrdého. Tvrdý oficiálně sleduje genetický, revizionistický projekt, který však nespadá vjedno s antireprezentacionalismem. Avšak v jeho knize najdeme i stopy konstruktivního naturalismu. The paper distinguishes several versions of contemporary naturalism: revisionary, constructive, and non-representational. Revisionary naturalismus pleads substituting the traditional philosophical inquiry into the nature of things by a genetic inquiry into the origin of our – often faulty – beliefs about the nature of things. Constructive naturalism accepts the program of traditional philosophy, yet hoping that its questions could be answered by broadly scientific methods. Non-representational naturalism is an extension of metaethical expressivism, claiming that philosophical claims should not be understood as descriptive in nature. These distinctions can help us classify the most self-consciously naturalistic project in the recent Czech philosophy, Filip Tvrdý’s Troubles of Introspection (2015). Tvrdý is officially pursuing a genetic, revisionary project, which does not coincide with non-representational naturalism. However, there are also traces of constructive naturalism in Tvrdý’s book.
EDUKASI ORANG TUA UNTUK STIMULASI TUMBUH KEMBANG ANAK BALITA DENGAN TERAPI MUSIK
Authors: Sa'diya Lida , Tria wahyuningrum  
Published: April 2024

Faktor penentu bagi perkembangan anak baik fisik maupun mental adalah peran orang tua, terutama peran seorang ibu, karena ibu adalah pendidik pertama dan utama bagi anak-anak yang dilahirkan sampai dia dewasa. Salah satu faktor dalam meningkatkan pertumbuhan dan perkembangan anak adalah dengan memberikan stimulasi. Terapi musik memiliki banyak sekali manfaat, salah satunya untuk merangsang kecerdasan anak balita. Menurut ahli saraf dari Hardvard University, Mark Tramo, M.D., getaran musik yang masuk melalui telinga dapat mempengaruhi kejiwaan. Ini terjadi karena didalam otak manusia terdapat jutaan sel saraf (neuron) dari sirkuit secara unik menjadi aktif ketika kita mendengar musik. Neuron – neuron ini menyebar ke berbagai daerah di otak, termasuk pusat auditori di belahan kiri dan belahan kanan. Berdasarkan latar belakang masalah di atas dan mengingat pentingnya tumbuh kembang bagi anak, maka menarik untuk dilakukan pengabdian masyarakat tentang edukasi orang tua untuk stimulasi tumbuh kembang anak balita dengan terapi music.
Impact of Background Music on the Work-Life of Managerial and Non-Managerial Level Staff in a Sri Lankan Apparel Organisation: A Case Study
Authors: Kodikara Ridmi Senani 
Published: April 2024

Background music plays a pivotal role in organisational aesthetics. Hence, this research project attempts to identify how music has affected the different layers of staff in an organisation and whether it has had any positive influence on work-life in one of the leading organisations in Sri Lanka’s apparel sector. This study was designed using the single case study method as the qualitative method of inquiry. Leading Sri Lankan apparel manufacturers, Deadline Ltd. was chosen as the case unit concerning the unique application of background music. Semi-structured interviews and unstructured observations were incorporated into the study to gather data. During the semi-structured interview process, audio records were generated and converted to written form using a data transcribing process. Field notes were generated during the unstructured observation. The outputs were combined together to derive common themes and were analysed thoroughly. Most of the participants agreed that background music has a positive impact on their work-attributes by enabling psychological motives through reduction of job-related stress, tiredness and literary enjoyment, thus enabling positive motives for work. Indeed, referring to the findings, Deadline Ltd has designed its background music to cater to the choice of its diversified workforce. This has created a unique way of life for the staff layers in alliance with their socio-cultural status. Consequently, this has been influential in deriving different environmental stimuli that distinguish hierarchical differences. This has applied as a creative way of a communication system as well. Supplementary background music has reduced alienation while encouraging positive interaction among workers, enabling fresh routine for work-life within different work-shifts. Accordingly, Deadline Ltd has effectively tailored the arrangement of background music to address the diverse requirements of each staff audience to assimilate the aesthetic practices with the staff management strategy, minimising the possible of contradiction of different preferences. As such, this case study showcases the importance of unique musical arrangements, which can effectively interact with contextual differences. This study affirms that an ideal arrangement of background music can generate several favourable outcomes as a facilitator for employee performance, enabling positive outcomes for both employees and organisation simultaneously.
Keywords: Aestheticisation, Background-music, Work-Life, Managerial, Non-managerial
Modelling and Forecasting Tourist Arrivals in Sri Lanka by Purpose of Visit Using Box-Jenkins Methodology
Authors: Thilakarathna H.A.N. 
Published: April 2024

Tourism is a major source of income in Sri Lanka, which was described by the Italian explorer Marco Polo as ‘the finest island of its size on earth’ in the 13th century. Tourist attractions in Sri Lanka have many treasures, such as beaches, a favourable climate, cultural heritage, and national parks. These attractions are very important for the tourists who come to the country for pleasure. Tourists visit Sri Lanka not only for pleasure but also for other purposes. Therefore, this study was conducted to present a more accurate forecasting model of tourist arrivals by purpose of visit. The data were taken from the reports of the Sri Lanka Tourism Development Authority and annual arrivals from 2010 to 2017 were analysed by country of residence and selected four purposes of visit, which were pleasure/ vacation, visiting friends and relations, business and religious and cultural. According to these data, most tourists come for pleasure/ vacation and most of them are Asians. Further, it was found that India demonstrated the highest number of arrivals out of 11 Asian countries. Thus, monthly arrivals from India from 2010 to 2019 were gathered to model a forecasting model. According to the minimum Akaike Information Criterion (AIC) and Bayesian Information Criterion (BIC) values, SARIMA (Seasonal Autoregressive Integrated Moving Average) (1,1,1)(0,0,2)12 was selected as the best model to forecast tourist arrivals from India. In this study, forecasting was done for the year 2020.
Keywords: Asians, Forecast, Pleasure, Purpose, Tourist Arrivals
Role of the Structural and Functional Genes Encoding Heat Shock Proteins in Biosurfactant Synthesis by <i>Rhodococcus</i> <i>pyridinivorans</i> 5Ap
Authors: Bukliarevich H. A. , Titok M. A. 
Published: April 2024

Abstract—The role of groESL and dnaJ structural genes and hrcA regulatory gene, encoding the synthesis of heat shock proteins, in biosurfactant synthesis by R. pyridinivorans 5Ар was determined. The CIRCE binding sites for the regulatory protein coded by hrcA gene were revealed in the promoter regions of groESL, groEL2, and fmdB genes. GroESL and groEL2 genes expression during the late exponential phase in the medium with hexadecane at 42°C was higher than at 28°C (4.4 and 5.3 times, respectively). At the same time, no changes in expression of hrcA and fmdB genes were observed at two different temperature modes (28 and 42°C). In the absence of the negative regulator HrcA, groESL expression increased 14.4 and 3.5 times, that of groEL2, 9.6 and 2.7 times, and that of fmdB, 1.82 and 2.52 times at 28 and 42°C, respectively. Products of dnaJ and hrcA genes were required for trehalolipid synthesis at different temperature modes, with their role increasing at higher temperature (synthesis of trehalolipids by the mutant with impaired dnaJ gene decreased 1.8 and 2.5 times compared to 1.5 and 6.6 times, for the mutant with impaired hrcA at 28 and 42°C, respectively). At the same time, emulsifying activity of all mutant variants did not change at 28°C and decreased 1.4 and 1.9 times 42°C for the mutants with impaired groESL and hrcA genes, respectively. Our results indicated the complex chemical nature of the biosurfactants produce by R. pyridinivorans 5Ар (emulsifiers, including trehalolipids and compounds of other chemical composition). The Gro chaperones and the HrcA regulatory protein play the key roles in synthesis of these compounds at different temperature modes, while the dnaJ is required only for trehalolipid synthesis.