bluuebunny/crossref_metadata_2025_split huggingface dataset:
Rhinocerebral phycomycosis
Authors: Yanagisawa Eiji , Friedman Stanley , Kundargi Ronald S. , Smith Howard W. 
Published: July 2007

AbstractRhinocerebral phycomycosis is an uncommon but important pathologie entity with a rapidly fatal course if treatment is delayed. Successful therapy demands early diagnosis and institution of adequate treatment if complications are to be avoided.Two cases of rhinocerebral phycomycosis which demonstrate the rapidly progressive and devastating nature of this disease are presented.The first case is that of a rapidly progressive rhinocerebral phycomycosis with the classical syndrome of diabetic acidosis, unilateral blindness, ophthalmoplegia and proptosis. Early diagnosis, immediate surgical de‐bridement and Amphotericin B therapy resulted in a long‐term (five years) survival.This case is also unique in that a large fungal mass was found within the sphenoid sinus, which was removed via sphenoidotomy. If the sphenoid sinus had not been opened and the mass not removed at surgery, this could have been the source of continued infection in spite of Amphotericin B treatment. If preoperative X‐rays show cloudiness of the sphenoid sinus, sphenoidotomy is recommended.The second case illustrates a fatal course of rhinocerebral phycomycosis in which surgical treatment was refused. This leukemie patient died within one week from the onset of the disease. Autopsy showed extensive fungal involvement of the posterior orbital contents, ethmoid sinuses, leptome‐ninges and cerebrum with thrombosis of the right internal carotid artery and meningoencephalitis. Histological sections showed nonseptate hyphae in the wall and lumen of vessels, occular muscles, optic nerve sheath, leptomeninges, and cerebrum. No leukemie infiltrates were observed in either the brain or orbit.Clinicopathological features of phycomycosis are discussed and the need for early diagnosis is stressed.The most frequent manifestations of rhinocerebral phycomycosis are: 1. diabetic ketoacidosis; 2. blepharoptosis; 3. ophthalmoplegia; i. “black” turbinate (may appear “pale” when seen early); 5. X‐ray evidence of cloudiness of the involved sinuses without fluid level; and 6. signs of cerebrovascular thrombosis (CVA) with meningoencephalitis.Treatment consists of: 1. control of systemic disease; 2. debridement of involved tissues; and 3. Amphotericin B.
Motivation in hearing aid acceptance
Authors: Vernon Sally M. , Pratt Lindsay L. 
Published: July 2007

AbstractPatient case histories are presented in an attempt to pinpoint possible motivational factors affecting the acceptance of a hearing aid. Personality profiles were constructed on three representative patients through the use of an in‐depth interview as well as three personality scales: the 16 Multiphasic Personality Scale; the Crowne‐Marlowe Social Desirability Scale; and the Attitude Toward Disabled Persons Scale. The very preliminary results indicate at least some face validity to the assertion that unsuccessful hearing aid wearers are measurably different from successful wearers and that these differences may be used to predict success or failure for future patients.
Secondary phase nystagmus—revisited
Authors: Kameker Donald B. , Rood Stewart R. , Thompson James N. 
Published: July 2007

AbstractA prospective clinical study of secondary phase nystagmus (SPN) is presented. The tracings of 200 patients referred for ENG evaluation and eight normal control subjects were analyzed under all caloric conditions, within a prolonged postirrigation tracing time frame. The spontaneous direction reversal (SPN) was observed in a majority of the control subjects under all four conditions. The occurrence of post‐caloric SPN in the patient group varied considerably among various diagnostic categories. However, SPN was observed far less frequently in the total patient group as compared to the control group. Thus, the absence of SPN may be taken to be a general indication of vestibular pathology.
The microbiology of chronic middle ear effusions in children
Authors: Healy Gerald B. , Teele David W. 
Published: July 2007

AbstractSerous otitis media is the most common cause of hearing loss in childhood. Traditionally, this entity has been felt to be a sterile process.This study was undertaken to determine the incidence of infected middle ear fluid in patients with asymptomatic middle ear effusions.The external auditory canal, nasopharynx and middle ear fluids of 57 patients undergoing myringotomy were cultured. Of 57 patients, 26 had positive cultures; 67% of patients less than 36 months of age had positive cultures, with a bacterial flora closely resembling that of acute otitis media.Further investigation is required to determine the significance of such infection together with the optimum therapy for chronic effusions of the middle ear in young children.
Treatment of severe tinnitus with biofeedback training
Authors: House John W. 
Published: July 2007

AbstractTinnitus has long been a problem which has plagued patients with otologic problems. We have been using biofeedback as a method of treatment for patients with severe debilitating type tinnitus. Most of the patients had sensori‐neural type hearing impairment while a few had conductive hearing loss and normal hearing. The patients were given 10&12 one hour sessions of biofeedback training. They have been followed from 6 to 12 months after this initial training period. Over half of the patients participating in the study report an improvement in their condition. A few of the patients were dramatically improved while none are worse. Biofeedback has been shown to be an excellent method of treatment for patients with severe tinnitus.
Symposium on hearing loss ‐ The otolaryngologist's responsibility.: Medical management of hearing loss.
Authors: Meyerhoff William L. 
Published: July 2007

AbstractMillions of Americans suffer hearing loss resulting in immense social and economic consequences. Hearing loss is merely a symptom or sign and the evaluation and management of afflicted individuals requires a thorough knowledge of etiologic factors and understanding of the underlying pathophysiology. Hearing loss is either conductive, sensorineural, or mixed. It may be congenital or delayed in onset, genetic or nongenetic, and progressive or stable. Specific diagnosis should be sought in all cases with the objective being reversal of the hearing loss. Often definitive therapy is lacking yet prevention of progression, when possible; recognition of associated disorders, when present; compensation for disability, when applicable; epidemiologic study; genetic and psycho‐social counseling; and habilitation and rehabilitation may still be initiated. A vigorous approach to the patient with hearing loss should be championed by the otolaryngologist.
Symposium on hearing loss ‐ The otolaryngologist's responsibility.: Habilitation and rehabilitation of patients with sensorineural hearing losses.
Authors: Carney Arlene Earley 
Published: July 2007

AbstractA philosophy of the (re)habilitation of patients with sensorineural hearing losses from a communication point of view is presented. Pediatric and adult populations are discussed separately. Topics of consideration for pediatric patients include the appropriate use of amplification, team management of the hearing handicap, educational placement and the importance of parent counseling. The discussion of the management of adult patients reviews some problems in hearing aid fitting, patient counseling and appropriate case follow‐up. The guiding principle behind these (re)‐habilitation processes is the integration of the hearing‐impaired patient into a hearing world.
57Co‐Bleomycin imaging study of tumors of the head and neck.
Authors: Sawas‐Dimopoulou Christine , Pantazopoulos Panos , Dokianakis George , Apostolopoulos Nicolas , Papafrangou Constantine 
Published: July 2007

Abstract57Co‐Bleomycin (57Co‐BLM) was used to visualize malignancies of the head and neck because it does not present the disadvantages of many other radiopharmaceuticals. In a series of 21 patients with 9 control subjects and 12 cases of tumors. 57Co‐BLM showed a high and rapid uptake in primary site and metastases of malignant tumors of various histologic types, but not in benign tumors such as angiofibromas. Compared to 67Ga‐citrate. 57Co‐BLM has many advantages for tumor imaging in the areas of nose, pharynx and larynx: No background activity due to the concentration of 57Co‐BLM in normal structures of the head and neck has ever been observed, as opposed to what happens with 67Ga‐citrate. Furthermore, the blood clearance of 57Co‐BLM is much more rapid than that of 67Ga‐citrate, so that an early study may be performed in a 6‐24 hr. interval instead of 48–72 hr. with 67Ga‐citrate. 57Co‐BLM scintigraphy is an easy, non‐invasive and sensible diagnostic technique in determining the extent of malignant tumors in ORL patients.
A Novel Culture Technique for Human Embryonic Stem Cells Using Porous Membranes
Authors: Kim Sinae , Ahn Seong Eun , Lee Jae Ho , Lim Do-Seon , Kim Kwang-Soo , Chung Hyung-Min , Lee Soo-Hong 
Published: July 2007

Abstract
We have developed a novel culture technique for human embryonic stem cells (hESCs) using a porous membrane with feeder cells. The feeder cells were seeded and attached to the bottom of a porous membrane and, subsequently, hESCs were cultured on the top of the membrane. This porous membrane technique (PMT) allowed hESCs to be successfully cultured and to be effectively and efficiently separated from the feeder cell layer without enzyme treatment. hESCs being cultured by PMT were observed to interact with feeder cells through pores of membrane, where the interaction was dependent on the pore size of the membrane used. It was also revealed that the number of attached hESC colonies depended on the concentration of feeder cells on the bottom of the membrane. On the other hand, hESC colonies did not attach to porous membrane, as feeder cells were in the presence of culture dish, not the porous membrane. The hESCs cultured on porous membranes not only exhibited expression of several undifferentiated markers and a normal karyotype, but they also formed teratomas consisting of three germ layers in in vivo study. Compared with the mechanical isolation technique conventionally used, PMT significantly decreased mouse vimentin gene expression in cultured hESCs. Thus, a PMT for hESC culture would be a useful tool to exclude enzyme treatment and to reduce contamination from feeder cells simultaneously.
Disclosure of potential conflicts of interest is found at the end of this article.