bluuebunny/crossref_metadata_2025_split huggingface dataset:
Exploring safety at mass gathering events through the lens of three different stakeholders
Authors: Hutton Alison , Robertson Martin , Ranse Jamie 
Published: February 2025

IntroductionThe work here reviews the role of those with responsibility in managing people and their safety at Mass Gathering Events (MGE); event managers, police, and medical personnel. This paper comes at a time when there is an acute need for appropriate application of psychosocial understanding and biophysical knowledge for the safe management of the social environment of MGE, and the broader community. Safety has become increasingly significant in the vocabulary of researchers, managers, funding agencies and public bodies involved in the provision of mass gathering events.MethodFocus groups were used to gain insight into MGE safety through the lens of three different groups. Through prioritising safety at mass gathering events, organisers enhance the quality of the event, protect individual and promote the long-term success of the event. Questions were centred on their understanding of safety at events, based on their experiences in MGEs.ResultsParticipants in this study identified many risks to event safety, including lack of risk assessment, communication, lack of ownership of risk and poor planning. Even though these risks were similar, each participant group identified their own perspective with their own ways of managing them.DiscussionThe work proposes that all event stakeholders should focus on the interests of both the audience and the broader event community, with the goal of working together to foster a safe, supportive, and trusting environment. Building trust in the context of mass gathering events brings forward an opportunity for new orientation strategies. A framework for developing personal skills and community resilience for mass gathering events is shown.
Microbial partner (MiPner) analysis
Authors: Bennetzen Jeffrey L. , Fernandez-Canela Josue , Elmgreen Vienna , McCann Shaugnessy R. , Norris Mary E. , Deng Xiangyu , Brailey-Crane Philip 
Published: February 2025

IntroductionAlthough a few bacteria have been studied in great depth, relatively little is known about the characteristics of microbe-microbe interactions that occur within ecosystems on a daily basis. A simple, robust technique was developed to set up the foundation for investigating pairwise bacterial-bacterial interactions, using cell-cell binding as a self-selective mechanism to identify interesting bacterial species pairs.MethodsUsing a Serratia marcescens strain (SMC43) isolated from Georgia soil as a “bait”, specific bacteria were purified by their specificity in binding SMC43 bacteria that were themselves attached to a wooden applicator stick.ResultsThe isolated Microbial Partners (MiPners) were greatly enriched for members of the genera Sphingobium and Caulobacter. Two streaked MiPners were unable to grow on the plates employed after separation from SMC43to be separated from, and grow on the plate type tested without, SMC43.DiscussionThis suggests that the MiPner technology will be one strategy for purifying bacteria that were previously recalcitrant to culturing.
Pressure-driven polymeric membrane performance prediction, new membrane dimensionless number, and considerations for effective membrane design, selection, testing, and operation
Authors: Anim-Mensah Alexander R. 
Published: February 2025

The demand for polymeric membranes in industries such as fine chemicals, petroleum, and pharmaceuticals underscores the need to optimize organic separation systems. This involves enhancing performance, longevity, and cost-efficiency while tackling chemical and mechanical instabilities. A model is here developed which relates membrane performance, indicated by the permeate solute concentration (Cpi) of species i, to the real-time compressive Young’s modulus (E) during compaction with permeation under a transmembrane pressure (ΔP) or compressive stress. Lower Cpi values indicate better performance. The model integrates solvent densities (ρi), solubility parameters of the membrane (δM), solute (δSo), solvent (δSv), and the extent of membrane constraint (ϕ). It also considers membrane swelling (Ls) and compaction (Lc) with the associated Poisson ratio (γ), providing a comprehensive framework for predicting membrane performance. A key feature is the dimensionless parameter β, defined as ln (Ls/Lc), which describes different operational regimes (β &lt; 1, β = 1, β &gt; 1). This parameter connects membrane affinity characteristics with mechanical properties. The model’s capabilities were demonstrated using three organic separation systems (A, B, and C) which separated isoleucine from DMF, methanol, and hexane solutions, respectively, using nanofiltration (NF) membranes with low, medium, and high E values. The transmembrane pressure ranged from 0.069 to 5.52 MPa (10–800 psi) for β &lt; 1. The performance results indicate that the trend of System B (medium E) &gt; System A (low E) &gt; System C (high E), correlating to decreasing solvent–solute interactions (ΔδSoSv) and compaction levels. Moderate compaction, resulting in moderate membrane resistance and densification, proved beneficial. Cpi–β plots revealed three distinct slopes, corresponding to elastic deformation, plastic deformation, and the densification of membrane polymers, thus guiding optimal ΔP ranges for operation. This model paves the way for advancing polymeric pressure-driven membrane research and offers new insights into membrane selection, testing, design, and operation.
Prevalence of Japanese encephalitis in pigs in Mainland China during 2000–2024: a systemic review and meta-analysis
Authors: Liu Xue-Tong , Jiang Li-Dong , Lin Yu-Ting , Zhao Ran , Wang Qi , Zhang Shu-Ying , Ata Emad Beshir , Liu Xin , Wang Yuan , Liu Zi-Xuan , Xu Cui , Xiao Ying , Wang Yi-Fan , Leng Xue , Gong Qing-Long , Du Rui 
Published: February 2025

BackgroundJapanese encephalitis (JE) is an acute viral disease transmitted mainly by mosquitoes, primarily affecting Southeast Asia, and the Western Pacific. This study aimed to analyze the factors contributing to JE occurrence in pigs across China.MethodsA systematic search was done using six databases for the published epidemiological studies on porcine JE, including the Chinese Web of Knowledge (CNKI), Wan Fang Database, ScienceDirect, Web of Science, VIP Chinese Journal Database, and PubMed.ResultsA meta-analysis of 31 studies from 2000 to 2024 found an overall prevalence of 35.2% (95% CI: 25.1–46.1). The highest prevalence occurred between 2010 and 2015 at 53.4% (95% CI: 44.2–80.6), from 2010 to 2015, increased precipitation and favorable annual temperatures led to the proliferation of mosquitoes, causing Japanese Encephalitis outbreaks among swine. While the lowest was 2.5% (95% CI: 0.2–6.6) in temperate climates. Serum samples showed the highest prevalence 38.1% (95% CI: 27.9–48.9), and ELISA testing had a higher detection rate 38.2% (95% CI: 24.5–52.9). In the farming mode subgroup, the highest prevalence was observed in the large-scale farming mode at 40.9% (95% CI: 26.4–66.3).ConclusionThe study highlights the spread of JE across China and suggests that it may be underrecognized in some areas. Continuous monitoring and improvements in farming practices are essential for controlling the disease.
Community Use and Perceptions of Climate Shelters in Schoolyards in Barcelona
Authors: Sanz-Mas Marta , Continente Xavier , Marí-Dell’Olmo Marc , López María José 
Published: February 2025

ObjectivesThis study explores the use and perceptions of thermal comfort and wellbeing among the local community in the schoolyards in Barcelona that had been transformed into accessible climate shelters.MethodsWe conducted a qualitative evaluation through a spontaneous ethnographic approach, combining 22 non-participant observations in the 11 transformed schoolyards with brief spontaneous interviews with 76 users and 18 caretakers who supervised the schoolyards during non-school days (June–July 2022). We conducted a thematic content analysis. We analyzed user characteristics, thermal comfort and wellbeing, activities and differences by age and gender, social behavior, additional benefits, and areas for improvement.ResultsAdapted schoolyards were mostly visited by families and groups of adolescents with a higher proportion of boys. Participants reported that shade provided coolness and comfort, vegetation offered pleasant and naturalized environments, and water features were enjoyed for their cooling capacity and play opportunities. Schoolyards were mainly used as places for outdoor recreation and socialization.ConclusionThis study provides policymakers with evidence to support the transformation of schoolyards into climate shelters, creating comfortable outdoor recreational areas for the surrounding urban community.
Feeding Habits of the Invasive Ctenophore Mnemiopsis leidyi in the Gulf of Trieste (Adriatic Sea)
Authors: Mavrič Borut , Ivajnšič Danijel , Lučić Davor , Malej Alenka , Lipej Lovrenc 
Published: February 2025

The diet of the invasive ctenophore Mnemiopsis leidyi in the Gulf of Trieste was examined during its peak occurrence in the summer and early-autumn months (July to October) from 2017 to 2019, through the analysis of stomach contents. Altogether 506 specimens were individually caught for the analysis. A total of 3215 prey items were isolated and identified. Copepods emerged as the primary prey (relative abundance 66.7%), followed by cladocerans (7.7%), and bivalve larvae (6%). Notably, specimens of M. leidyi constituted a significant portion of the diet (5.4.%), providing further evidence of cannibalism within this species. Copepods were also the most commonly occurring prey items in the diet of M. leidyi. Most of them were represented by calanoid and cyclopoid nauplii (48.2%), followed by a harpacticoid M. norvegica (28.3%), and calanoids (26.8%). Other frequently occurring taxa were bivalve larvae (19.3%), M. leidyi (18.7%), and cladoceran Penilia avirostris (16.1%). The rate of cannibalism peaked in July, coinciding with a period of limited food availability. Additionally, the study revealed that fish eggs and larvae were infrequently found in the stomachs of M. leidyi. However, the presence of massive aggregations of M. leidyi may impact microzooplankton populations in late summer or autumn, potentially leading to competition with small pelagic fish.
Análise epidemiológica do câncer de pulmão no Brasil em função do aumento do uso de cigarro eletrônico nos anos de 2017 a 2022
Authors: Araújo João Victor Barros , Freitas Pedro Henrique Menezes de , Garcia Luis Fernando Burgos , Silva Marlon Maia da , Silva Maycon Maia da , Teixeira Luciano de Castro Resende Araújo , Rocha Diogo dos Santos , Chagas Anelyse Soares , Queiroz Gustavo Luis Mota de , Silva Iran Miranda 
Published: February 2025

Introdução:O câncer de pulmão é a principal causa de morte por câncer no Brasil e o tumor maligno mais letal entre os homens no mundo. Nos últimos anos, o aumento do uso de cigarro eletrônico no país tem se tornado uma preocupação, já que sua relação com o desenvolvimento da doença vem sendo cada vez mais evidenciada. Objetivo: Definir o perfil epidemiológico do Câncer de pulmão no Brasil no contexto do aumento do uso de cigarro eletrônico.Métodos:Trata-se de perfil epidemiológico horizontal retrospectivo que utiliza dados do datassus e do INCA, foram utilizados os parâmetros da temporalidade em relação ao uso de cigarro eletrônico nos anos de 2014 a 2022.Resultado:Em 2022,o Brasil registrou mais de 62 mil casos de câncer de pulmão, com um aumento em relação a 2017.No mesmo período, o uso de cigarro eletrônico entre jovens de 15 a 24 anos cresceu 300% entre 2015 3 2019, indicando uma possível correlação.Discussão:A análise dos dados revelou uma relação direta entre o aumento do uso do cigarro eletrônico entre jovens e o crescimento das internações por câncer de pulmão.A faixa etária mais acometida foi de 15 a 24 anos, evidenciando o impacto do cigarro eletrônico na incidência da doença.Conclusão: O estudo evidencia a relação entre o aumento câncer de pulmão e o uso de cigarro eletrônico, especialmente entre jovens de 15 e 24 ano, e busca incentivar políticas públicas e pesquisas para prevenção e conscientização sobre os riscos.
EFEKTIFITAS METODE FOCUS GROUP DISCUSSION (FGD) DALAM MENINGKATKAN PENGETAHUAN, SIKAP DAN PERILAKU PADA ORANG TUA PEDULI ANAK THALESEMIA
Authors: Wahyudi Wahyudi , Subandiyo Subandiyo , Mardiyono Mardiyono , Kuswati Ani , Widjijati Widjijati 
Published: February 2025

Pendahuluan: Dinas Kesehatan Banyumas ada 1.000 sekian kasus Thalasemia di Jateng, 243 kasus diantaranya ada di Banyumas. Kondisi perawatan berulang, lama, membosankan pada penderita talasemia menyebabkan penyakit ini mencakup semua aspek kehidupan individu. Keluarga membutuhkan pemahaman penyakit thalasemia, cara pengobatan, tindakan pencegahan yang dapat diterapkan saat merawat di rumah sehingga diperlukan salah satu pelayanan kesehatan melalui Focus Group Discussion (FGD). Tujuan penelitian mengevaluasi FGD terhadap pengetahuan, sikap dan perilaku orang tua peduli anak Thalasemia. Metode: Jenis penelitian quast experimental, with control group design dengan pre - test – post – test. teknik consecutive sampling, consecutive sampling (berurutan), total sempel ada 60 responden, sebanyak 30 untuk kelompok perlakuan dan 30 untuk kelompok kontrol. Berdasarkan hasil analisis terdapat pengaruh promosi kesehatan dengan metode FGD terhadap pengetahuan masyarakat tentang thalasemia. Terdapat pengaruh promosi kesehatan dengan metode FGD terhadap pengetahuan masyarakat tentang diabetes mellitus. Hasil :Untuk analisis bivariate, peneliti menggunakan uji pairesd sample T Test didapatkan nilai p value pengetahuan = 0,001 lebih kecil dari nilai alpha (p < 0,05), sikap (p<0,01) dan perilaku (p 0,01) hal tersebut menunjukkan ada pengaruh pengetahuan, sikap dan perilaku sebelum dan setelah diberikan pendidikan kesehatan dengan metode Focus group discussion. pada orang tua peduli anak thalassemia. Kesimpulan: Berdasarkan hasil penelitian ini, dapat dilakukan penelitian lebih lanjut dengan metode lain seperti metode bermain, metode peer education
Gambaran Hubungan Obesitas dan Diabetes Melitus pada Pasien Diabetes Mellitus RSUD Koja Tahun 2004 - 2008
Authors: . Herbert , Santoso Mardi 
Published: February 2025

AbstrakÂ Obesitas adalah akumulasi lemak tidak normal atau berlebihan di jaringan adiposa. Obesitas dapat meningkatkan resistensi insulin. Penelitian ini bertujuan untuk mempelajari korelasi antara obesitas dan Diabetes mellitus (DM). Penelitian dilakukan secara cross sectional dan pengambilan data dilakukan secara acak. Uji korelasi dilakukan dengan chi square. Data diambil dari rekam medik pasien yang dirawat di bagian penyakit dalam RSUD KOJA tahun 2004 â€“ 2008. Dari 78 sampel, sebanyak 36 pasien dengan obesitas menderita DM sementara 10 pasien obes tidak menderita DM. Dari 73 pasien DM, 12 tidak obes, sedangkan pasien yang tidak menderita DM dan tidak obes sebanyak 20 pasien. Disimpulkan bahwa terdapat hubungan antara obesitas dan DM. Â Kata kunci: diabetes, obesitasÂ Â Abstract Â Obesity, in which fat is abnormally accumulated at adipose tissue, will increase insulin resistance syndrome. This study learned the correlation between obesity and DM. This research was cross sectional with the data taken by random sampling method. Chi square was used to test the correlation. The data were taken from medical records of all interne ward patients in RSUD KOJA from 2004 â€“ 2008. Out of 78 samples, 36 obese patients suffered from DM and 10 obese patients were found without DM. From 73 DM patients, 12 were not obese while the number of patients without DM and without obesity was 20 patients.Â Key words: Diabetes, obesity
Komplikasi Retinopati Diabetik Gambaran Klinis dan Sebaran Prevalensi Pasien Rawat Jalan dan Rawat Inap Di RSUD Koja Periode Januari 2004 â€“Desember 2008
Authors: . Ronald , Ndraha Suzanna , Santoso Mardi , Morosidi Saptoyo Argo 
Published: February 2025

AbstrakRetinopati diabetik adalah komplikasi paling penting dalam diabetes mellitus karena prevalensinya yang tinggi. Tingkat gula darah meningkatkan faktor resiko. Pasien dengan retinopati diabetik beresiko mengalami kebutaan. Studi ini bertujuan untuk mempelajari prevalensi retinopati diabetik dihubungkan dengan faktor yang dapat dikontrol (tekanan darah dan gula darah puasa) dan faktor yang tidak dapat dikontrol (umur dan jenis kelamin). Untuk mendiagnosa retinopati diabetik digunakan standar yang diusulkan oleh Early Treatment Diabetic Retinopathy Study Research Group (ETDRS). Studi ini dilakukan secara cross-sectional. Data diambil berdasarkan rekam medis seluruh pasien DM dari Januari 2004â€“Desember 2008 di RSUD Koja. Retinopati Diabetik kebanyakan terjadi pada laki-laki (96 pasien, 59.26%) dibanding pada wanita (66 pasien, 40,74%). Kelompok umur 50-59 tahun beresiko lebih tinggi (38,27%) daripada kelompok umur lain. Retinopati diabetik terjadi sebanyak 67.9% pada pasien dengan kadar gula darah puasa 100 mG/dL dan gula darah sewaktu 140 mG/dL.Kata kunci: retinopati diabetik, prevalensi, komplikasiÂ Â AbstractDiabetic Retinopathy is the most important complication in diabetes mellitus (DM) because of its high prevalence. The risk factor is elevated blood sugar. Patients with diabetic retinopathy are at risk of blindness. This study was aimed to find out the prevalence of Diabetic Retinopathy related to unmanageable factors (age and sex) and manageable factors (blood pressure and fasting blood sugar). Classification proposed by Early Treatment Diabetic Retinopathy Study Research Group (ETDRS) was used for diagnosing diabetic retinopathy. This study was cross sectional and was based on medical data record on all DM patients from January 2004 â€“ Desember 2008 in RSUD Koja. Diabetic Retinopathy mostly happens in male (96 patients, 59.26%) compare to female (66 patients, 40,74%). Age group of 50-59 years old has a higher risk (38,27%) than the other age group. Diabetic Retinopathy happened 67.9% in patients with blood sugar level of 100 mG/dL (fasting) and 140 mG/dL Key words : retinopathy diabetic, prevalence, complication
Penanda Biologis Protein Tau pada Demensia Alzheimerï»¿ï»¿ndo
Authors: Ingkiriwang Elly 
Published: February 2025

AbstrakPada penyakit Alzheimer (AD) ditemukan kerusakan neuron di tingkat seluler, terutama pada korteks dan hipokampus. Beberapa penyebabnya antara lain oleh deposisi protein amiloid di luar sel neuron yang disebut plak, dan perubahan yang ditemukan di dalam sitoplasma disebut sebagai Neurofibrillary Tangles (NFT).1 Penelitian selama beberapa dekade ini telah memfokuskan pada Cerebrospinal Fluid (CSF) sebagai jendela dari otak individu dengan AD dan beberapa penyakit yang berhubungan dengannya. Patobiologi neurodegenerasi telah dimengerti dengan lebih baik, dan investigasi mulai difokuskan pada CSF sebagai protein penanda biologis untuk demensia Alzheimer. Tiga penanda biologis seperti total tau,fosfo-tau, dan bentuk asam amino 42 dari ÃŸ-amyloid telah dipelajari dalam sejumlah studi dan kemampuannya untuk mengidentifikasi AD incipient pada kasus Mild Cognitive Impairment (MCI). Penanda biologis CSF diharapkan mempunyai kemampuan tidak hanya sebagai penanda diagnostik, tetapi juga sebagai penanda stadium atau aktivitas penyakit. Tau dalam CSF meningkat pada tahap sangat dini, mungkin mendahului demensia yang dapat terdeteksi secara klinis. Diagnosis klinis AD dapat dilakukan dengan akurat, terutama oleh klinisi yang berpengalaman, dan karena hanya pengobatan simptomatik yang tersedia, maka test CSF untuk AD jarang dilakukan sebagai alat diagnostik yang rutin.2 Pengobatan simptomatik sekarang dapat memperlambat progesivitas penyakit3, maka test CSF dilakukan untuk diagnostik dini, bahkan presimptomatik sehingga akan lebih luas digunakan dalam praktek klinis.Â Kata kunci: penyakit Alzheimer, CSF, penanda biologis, tau.
Ketoacidosis a Rare Complication of Fibrocalculous Pancreatic Diabetes
Authors: Tan Henny Tannady , Ndrah Suzanna 
Published: February 2025

AbstractÂ In a tropical country a case of ketosis resistant insulin dependent diabetes mellitus occurred in young lean patient who also shows evidence of malnutrition and pancreatic calculi with or without fibrosis and intermittent abdominal pain could be regarded as Fibrocalculous Pancreatic Diabetes (FCPD). We reported of a 24 years old female patient with shortness of breath since one day before she was admitted to the hospital. She also had a fever with sore throat and recurrent abdominal pain. Patient had history of abdominal pain, at that time she also developed white stools. She had a two years history of generalized body weakness associated with progressive weight lost, polydipsia and polyuria.Physical examination revealed a young lady with a low Body Mass Index (BMI) and tonsilopharyngitis. The haematological examination shown hyperglycemia, ketoacidosis, and leukocytosis. The abdominal x ray and ultrasound scan showed pancreatic calcification. The classical clinical picture of FCPD is primarily of a young diabetic patient presenting with recurrent epigastric pain, steatorrhoea, signs of malnutrition and micronutrient deficiencies. Although this case caused by ketoacidosis resistant, under special circumstances particularly after stress for example infection, trauma, etc ketosis could also be occurred.Key word: ketoacidosis, complication, fibrocalculous pancreatic diabetesÂ AbstrakÂ Di negara tropis, kasus resistensi terhadap ketosis yang terjadi pada pasien diabetes mellitus tipe 1 (DMT1) berusia muda, bertubuh kurus, dan disertai penyulit berupa malnutrisi dan batu pankreas dengan atau tanpa fibrosis dan nyeri abdomen intermiten, dapat disebut sebagai Diabetes Melitus Terkait Malnutrisi (DMTM). Dilaporkan kasus seorang perempuan berusia 24 tahun dengan keluhan utama sesak nafas sejak 1 hari sebelum masuk RS. Keluhan juga disertai demam, sakit tenggorokan dan nyeri abdomen berulang disertai steatorroae. Sejak 2 tahun ini ia merasa badan lemas dengan penurunan berat badan progresif, polidipsi dan poliuri. Pemeriksaan fisik didapatkan Indeks Massa Tubuh (IMT) rendah dan tonsilofaringitis. Hasil laboratorium menunjukkan hiperglikemia, ketoasidosis, dan leukositosis. Foto polos dan USG abdomen menunjukan adanya kalsifikasi pankreas. Gambaran klasik dari DMTM adalah pasien DM muda dengan gejala nyeri epigastrium berulang, steatorroea, tanda-tanda malnutrisi dan defisiensi mikronutrien. Walaupun kasus ini disebabkan oleh resistensi terhadap ketoasidosis, namun pada kasus tertentu dengan penyulit seperti infeksi, trauma, dan sebab lainnya, ketosis dapat terjadi. Kata kunci: ketoasidosis, komplikasi, Diabetes terkait MalnutrisiÂ
Patofisiologi dan Patogenesis Kardiomiopati
Authors: . William 
Published: February 2025

Abstrak Kardiomiopati adalah sekumpulan kelainan pada otot jantung dan seringkali berakhir dengan gagal jantung. Penyakit ini diklasifikasikan berdasarkan bentuk perubahan anatominya menjadi tiga yaitu kardiomiopati dilatasi, hipertrofik dan restriktif. Etiologi dari masing-masing kardiomiopati sangat banyak dan sangat mungkin bertambah seiring bertambahnya ilmu pengetahuan dan beberapa pengetahuan mengenai penyakit ini yang masih perlu untuk diteliti lebih lanjut, pada makalah ini akan dibahas detail mengenai kardiomiopati dari aspek patofisiologi dan patogenesisnya.Â Kata kunci: Kardiomiopati, otot jantung, gagal jantungÂ Â Abstract Cardiomyopathy is a disease that affect heart muscle and often ended with heart failure. This disease can be classified into dilated, hypertrophic and restrictive type. The cause of each type is a lot and in time there will be added even more. This review will be discussed especially about the pathophysiology and the pathogenesis of the disease. Key words: Cardiomyopathy, heart muscle, heart failureÂ