bluuebunny/crossref_metadata_2025_split huggingface dataset:
Collaborating with the Dead
Authors: Green William David 
Published: April 2024

Abstract
Early modern dramatic co-authorship is traditionally thought of as a temporally and geographically synchronous process, yet recent advances in authorship attribution have increasingly considered later adapters who reshaped older plays for revival at much later dates. Their additions are often considered detachable from the original text, and scholarship has therefore largely focused on simply investigating the authorship of such alterations. Many plays, however, survive in adapted versions for which the identity of the adapters remains elusive. Analysing these adapters independently of identifiable authorship, this article argues that such adapters actively collaborated with a work's absent originator, supplying additions which pay attention to the play-text as a whole, thereby appropriating an old work for the requirements of a theatre company at much later moments in time.
Cardiomiopatia diabetică, factor structural aritmogen, implicații clinice | [Diabetic cardiomyopathy, structural factor and clinical implications]
Authors: Badea Anamaria Raluca 
Published: April 2024

Introduction: Diabetic cardiomyopathy is a distinct condition in diabetes and is independent of atherosclerotic coronary disease, having as an effect over time the onset of heart failure. Objective/Aims: This paper aims to analyze, based on the existing data in the specialized literature, the main myocardial structural changes in diabetic patients as well as the specific electrophysiological changes and their clinical impact. Materials and Methods: The study is based on articles published in MEDLINE/PubMed and Google Scholar. Results. Discussion: It has been shown that even from the pre-diabetic stage there is cardiometabolic damage followed by myocardial hypertrophy and progression to heart failure. However, in the early stage of diabetes, myocardial damage is discrete. As the metabolic disease progresses, the myocardial structural damage becomes irreversible. Conclusion: The active self-monitoring of glycemic values as well as the imaging evaluation by cardiac ultrasonography of all patients with metabolic syndrome even in the presence of normal glycemic values, in order to initiate the early initiation of specific antidiabetic therapy in order to prevent the occurrence of cardiovascular complications specific to this metabolic pathology
Rezumat
Introducere: Cardiomiopatia diabetică este o afecțiune distinctă în diabetul zaharat și este independentă de boala coronariană aterosclerotică, având ca efect în timp, instalarea insuficienței cardiace. Obiectiv principal al studiului:Această lucrare își propune să analizeze pe baza datelor existente în literatura de specialitate principalele modificări structurale miocardice la pacientul diabetic precum și a modificărilor electrofiziologice specifice și impactul clinic al acestora. Material și metodă: Bazele de date MEDLINE/PubMed au fost folosite pentru identificarea celormai relevante lucrări despre modificări structurale miocardice, electrofiziologia cardiaca specificala pacientul diabetic. Rezultate. Discuții: S-a demonstrat că încă din stadiul pre-diabetic există afectare cardiometabolică urmată de hipertrofia miocardică și progresia către insuficiența cardiacă. Cu toate acestea, în stadiul incipient al diabetului, afectarea miocardică este discretă. Pe măsură ce boala metabolica progresează deteriorarea structurală miocardică devine ireversibilă. Concluzii: Automonitorizarea activă a valorilor glicemice precum și evaluarea imagistică prin ultrasonografie cardiacă a pacienților cu sindrom metabolic chiar în prezența valorilor glicemice normale este utila în vederea inițierii precoce a terapiei specifice antidiabetice în scopul prevenirii apariției complicațiilor cardiovasculare specifice acestei patologii metabolice.
Gesundheitskompetenzen von Menschen mit „geringer Literalität“ – Subjektwerdung und Stigmamanagement im Kontext von „Doing Inability“
Authors: Heyrock Merle , Polat Ayca , Thege Britta 
Published: April 2024

In der Bundesrepublik Deutschland gelten nach den repräsentativen Daten der zweiten LEO-Studie aus dem Jahr 2018 ca. 12,1 % der erwerbstätigen Bevölkerung als „gering literalisiert“. Im Hinblick auf die Gesundheitskompetenz von Personen wird davon ausgegangen, dass sie einem sozialen Gradienten unterliegt und der Umgang mit Informationen über Gesundheit und Krankheit insbesondere für Menschen aus den sogenannten unteren Bildungs- oder Sozialschichten schwierig ist. Der Beitrag beschäftigt sich mit ersten Ergebnissen aus dem Forschungsprojekt „DiGeKo-Net“. Übergeordnetes Ziel des Forschungsprojektes ist es, für Menschen mit „geringer Literalität“ Zugänge zu gesundheitsrelevanten Informationen zu ermöglichen und eine spezielle App zu entwickeln, mit der ein konkreter Beitrag zur Förderung von Gesundheitskompetenzen geleistet werden kann. Hierzu wird eine an den Ressourcen der Teilnehmer*innen orientierte Forschungsperspektive verfolgt.
KEDUDUKAN HUKUM SURAT KEPUTUSAN KEPEGAWAIAN PEGAWAI NEGERI SIPIL SEBAGAI JAMINAN KREDIT
Authors: Turnip Anju Chornelus , Talubun Richardus F. 
Published: April 2024

Bank financial institutions have a role in developing the economic system. Banks have a role as distributors and collect funds from the public. The collection process involves receiving funds from the public in the form of savings. Meanwhile, in the process of distributing funds, banks provide credit to the public in the form of loans or credits. In providing credit, banks generally provide additional charges in the form of collateral. Guarantees are intended to provide certainty regarding the debtor's ability to pay off debts, which are also intended to avoid the risk of bad credit.
In the case of bad credit, collateral is used as a medium or object in resolving the problem. So in this case the collateral object must have value and can be transferred. Pay attention to this problem. The existence of a Civil Servant Decree as a collateral object in a credit agreement has various problems. This is based on the legal power of the Civil Servant Decree as an object for resolving credit disputes. A Civil Servant Decree is a letter containing the decision to appoint a Civil Servant along with other regulations relating to salary, rank, term of service and other rules relating to ethics
PENGARUH DIGITAL MARKETING, KUALITAS LAYANAN, DAN BRAND IMAGE TERHADAP KEPUTUSAN PEMBELIAN PRODUK KESEHATAN KLIKDOKTER DI INDONESIA
Authors: Ardiansyah Ardiansyah , . Fathorrahman , Pradiani Theresia 
Published: April 2024

Masyarakat yang membutuhkan layanan dan informasi kesehatan berbasis digital merupakan pelanggan utama dari aplikasi telemedicine seperti Klikdokter, maka dari itu Klikdokter harus mampu memastikan para calon pelanggan tersebut tertarik untuk menggunakan aplikasi Klikdokter untuk memenuhi kebutuhan kesehatan mereka tanpa harus datang langsung ke fasilitas kesehatan dengan berbagai aktivitas Digital Marketing, memberikan layanan yang berkualitas, dan Brand Image yang baik. Jenis penelitian ini ialah penelitian kuantitatif dengan kuesioner sebagai instrumen untuk pengumpulan data. Rumus Slovin digunakan untuk menghitung besar sampel dengan purposive sampling sebagai metode pengambilan sampel. Sebanyak 100 Pengguna aplikasi Klikdokter bersedia menjadi subyek penelitian. Analisis data yang digunakan dalam penelitian ialah analisis regresi linier berganda menggunakan perangkat lunak statistik. Hasil penelitian mengartikan yakni 1) terdapat pengaruh Digital Marketing terhadap keputusan pembelian produk kesehatan Klikdokter, 2) terdapat pengaruh kualitas layanan terhadap keputusan pembelian produk kesehatan Klikdokter, dan 3) terdapat pengaruh Brand Image terhadap keputusan pembelian produk kesehatan Klikdokter.
Perencanaan Strategis Pengembangan Usaha Ekonomi Mikro Islam di Koperasi Pesantren Al-Qodiri Jember
Authors: Villa Villatus 
Published: April 2024

Salah satu usaha yang termasuk unit ekonomi mikro Islam adalah koperasi syariah. Pada perkembangannya sampai saat ini, koperasi syariah menghadapi berbagai masalah, termasuk masalah pendanaan. Untuk menghadapi masalah tersebut, salah satu upaya strategis yang dapat dilakukan oleh adalah menerapkan perencanaan strategi yang baik agar dapat menentukan langkah yang yang tepat daam menghadapi segala permasalahan yang ada. Dengan demikian, penelitian ini bertujuan untuk mendiskripsikan perencanaan strategi pengembangan usaha ekonomi mikro Islam di koperasi Pesantren Al-Qodiri Jember. Metode penelitian yang digunakan dalam penelitian ini adalah menggunakan pendekatan kualitatif dan jenis penelitian studi kasus. Perencanan strategi pengembangan usaha ekonomi mikro Islam di koperasi Pesantren Al-Qodiri Jember melalui beberapa tahap, di antaranya: 1) analisis lingkungan baik lingkungan internal maupun eksternal koperasi pesantren Al-Qodiri Jember. 2) berdasarkan analisis SWOT posisi Koperasi Pesantren Al-Qodiri Jember berada pada kuadran II sehingga berada pada masa tumbuh dan membangun (grow and build). Strategi yang cocok bagi badan usaha yang berada pada posisi Grow and Build adalah strategi intensif diantaranya adalah a) Memperluas dan memperkuat jaringan dan kerja sama dengan semua pihak yang terkait; b) Pengembangan dan perluasan koperasi pesantren Al-Qodiri Jember; dan c) Perluasan ekspansi pasar di beberapa tempat di luar pesantren.
Disciplinary measures against persons in custody provided for by The Penitentiary Code of France: author’s translation and a brief comparative analysis with the provisions of the Russian penal enforcement legislation
Authors: Davydova Irina 
Published: April 2024

The article contains the text of the author’s translation of the section. III
«Disciplinary measures against persons in custody», contained in Book II «Detention in a penitentiary institution» of the Penitentiary Code of France. Within the framework of a brief comparative analysis, attention is drawn to a number of problems of law enforcement activities of the administration of correctional institutions in Russia related to the lack of proper legislative regulation of certain aspects concerning the grounds, types and procedure for the application of penalties, the need to improve the penal enforcement legislation of Russia taking into account foreign experience is noted.
Artificial intelligence-driven prognostic system for conception prediction and management in intrauterine adhesions following hysteroscopic adhesiolysis: a diagnostic study using hysteroscopic images
Authors: Li Bohan , Chen Hui , Duan Hua 
Published: April 2024

Introduction:Intrauterine adhesions (IUAs) caused by endometrial injury, commonly occurring in developing countries, can lead to subfertility. This study aimed to develop and evaluate a DeepSurv architecture-based artificial intelligence (AI) system for predicting fertility outcomes after hysteroscopic adhesiolysis.Methods:This diagnostic study included 555 intrauterine adhesions (IUAs) treated with hysteroscopic adhesiolysis with 4,922 second-look hysteroscopic images from a prospective clinical database (IUADB, NCT05381376) with a minimum of 2 years of follow-up. These patients were randomly divided into training, validation, and test groups for model development, tuning, and external validation. Four transfer learning models were built using the DeepSurv architecture and a code-free AI application for pregnancy prediction was also developed. The primary outcome was the model’s ability to predict pregnancy within a year after adhesiolysis. Secondary outcomes were model performance which evaluated using time-dependent area under the curves (AUCs) and C-index, and ART benefits evaluated by hazard ratio (HR) among different risk groups.Results:External validation revealed that using the DeepSurv architecture, InceptionV3+ DeepSurv, InceptionResNetV2+ DeepSurv, and ResNet50+ DeepSurv achieved AUCs of 0.94, 0.95, and 0.93, respectively, for one-year pregnancy prediction, outperforming other models and clinical score systems. A code-free AI application was developed to identify candidates for ART. Patients with lower natural conception probability indicated by the application had a higher ART benefit hazard ratio (HR) of 3.13 (95% CI: 1.22–8.02, p = 0.017).Conclusion:InceptionV3+ DeepSurv, InceptionResNetV2+ DeepSurv, and ResNet50+ DeepSurv show potential in predicting the fertility outcomes of IUAs after hysteroscopic adhesiolysis. The code-free AI application based on the DeepSurv architecture facilitates personalized therapy following hysteroscopic adhesiolysis.
The impact of high nicotine concentrations on the viability and cardiac differentiation of mesenchymal stromal cells: a barrier to regenerative therapy for smokers
Authors: Gheisari Maryam , Nosrati Shadi , Zare Shahrokh , Dara Mahintaj , Zolghadri Samaneh , Razeghian-Jahromi Iman 
Published: April 2024

Background: Current treatment methods are not successful in restoring the lost cardiomyocytes after injury. Stem cell-based strategies have attracted much attention in this regard. Smoking, as a strong cardiovascular risk factor, not only affects the cardiac cells adversely but also deteriorates the function of stem cells. Since mesenchymal stem cells (MSCs) are one of the popular candidates in cardiovascular disease (CVD) clinical trials, we investigated the impact of nicotine on the regenerative properties (viability and cardiac differentiation) of these cells.Methods: MSCs were isolated from rat bone marrow and characterized based on morphology, differentiation capability, and the expression of specific mesenchymal markers. The MTT assay was used to assess the viability of MSCs after being exposed to different concentrations of nicotine. Based on MTT findings and according to the concentration of nicotine in smokers’ blood, the growth curve and population doubling time were investigated for eight consecutive days. Cells were treated with 5-azacytidine (an inducer of cardiac differentiation), and then the expressions of cardiac-specific markers were calculated by qPCR.Results: MSCs were spindle-shaped, capable of differentiating into adipocyte and osteocyte, and expressed CD73 and CD90. The viability of MSCs was reduced upon exposure to nicotine in a concentration- and time-dependent manner. The growth curve showed that nicotine reduced the proliferation of MSCs, and treated cells needed more time to double. In addition, the expressions of GATA4 and troponin were downregulated in nicotine-treated cells on day 3. However, these two cardiac markers were overexpressed on day 7.Conclusion: Nicotine decreased normal growth and reduced the expression of cardiac markers in MSCs. This aspect is of eminent importance to smokers with cardiovascular disease who are candidates for stem cell therapy.
Medical communication, internalized “good mother” norms, and feminist self-identification as predictors of maternal burnout
Authors: Milman Daisy , Sternadori Miglena 
Published: April 2024

IntroductionA rarely studied source of psychological discomfort for mothers is the communication received from medical professionals in the context of pregnancy, childbirth, the postpartum period, and pediatric care. To address this gap, we examined mothers’ recollections of medical communications that influenced their perceived stress levels in the context of good-mother normativity. We also explored how recollections of feedback on mothering in medical settings were associated with internalization of good-mother expectations, maternal burnout, length of motherhood, and feminist self-identification.MethodsWe collected the data through an online survey administered by a company that pre-establishes business relationships with potential survey takers. The survey-takers were 254 self-identified mothers, who answered open-ended questions about their recollections of medical communications related to good-motherhood norms. The participants also completed measures of maternal burnout, internalized good mother expectations, and feminist self-identification, and answered demographic questions such as age, education, number of children, and how long they had been mothers.ResultsParticipants who recalled discomfort-inducing medical communications that directly or indirectly referenced motherhood norms reported higher levels of internalized good-mother expectations and maternal burnout. A process model showed that the frequency of recalled medical communications, length of motherhood, and feminist self-identification moderated the relationship between the degree of internalization of good-mother expectations and maternal burnout. A significant association emerged between feminist self-identification and the recalled frequency of interactions with medical professionals that increased mothers’ perceived stress stemming from good-mother normativity.DiscussionThe findings of this study contribute to self-discrepancy theory as it relates to the social construction of mothers’ identities by focusing on whether and how often medical professionals reinforce or challenge good-mother social expectations. Another theoretical contribution of this study is that values and beliefs, such as feminist self-identification, can affect the recall of communications about social norms and are significantly associated with levels of internalized expectations and resulting burnout. In terms of practical implications, our findings suggest that medical professionals should be mindful of how they assess patients through the lens of the good-mother norms and also consider addressing the discomfort stemming from such normativity by asking mothers about their perceptions of social expectations and addressing unrealistic beliefs that aggravate mothers’ sense of self-discrepancy.
Differences in perceived sources of uncertainty in natural hazards science advice: lessons for cross-disciplinary communication
Authors: Doyle Emma E. H. , Thompson Jessica , Hill Stephen R. , Williams Matt , Paton Douglas , Harrison Sara E. , Bostrom Ann , Becker Julia S. 
Published: April 2024

IntroductionWe conducted mental model interviews in Aotearoa NZ to understand perspectives of uncertainty associated with natural hazards science. Such science contains many layers of interacting uncertainties, and varied understandings about what these are and where they come from creates communication challenges, impacting the trust in, and use of, science. To improve effective communication, it is thus crucial to understand the many diverse perspectives of scientific uncertainty.MethodsParticipants included hazard scientists (n = 11, e.g., geophysical, social, and other sciences), professionals with some scientific training (n = 10, e.g., planners, policy analysts, emergency managers), and lay public participants with no advanced training in science (n = 10, e.g., journalism, history, administration, art, or other domains). We present a comparative analysis of the mental model maps produced by participants, considering individuals’ levels of training and expertise in, and experience of, science.ResultsA qualitative comparison identified increasing map organization with science literacy, suggesting greater science training in, experience with, or expertise in, science results in a more organized and structured mental model of uncertainty. There were also language differences, with lay public participants focused more on perceptions of control and safety, while scientists focused on formal models of risk and likelihood.DiscussionThese findings are presented to enhance hazard, risk, and science communication. It is important to also identify ways to understand the tacit knowledge individuals already hold which may influence their interpretation of a message. The interview methodology we present here could also be adapted to understand different perspectives in participatory and co-development research.
Changes in acromegaly comorbidities, treatment, and outcome over three decades: a nationwide cohort study
Authors: Rosendal Christian , Arlien-Søborg Mai Christiansen , Nielsen Eigil Husted , Andersen Marianne Skovsager , Feltoft Claus Larsen , Klose Marianne , Andreassen Mikkel , Bruun Niels Henrik , Jørgensen Jens Otto Lunde , Dal Jakob 
Published: April 2024

ObjectiveTo study the time-dependent changes in disease features of Danish patients with acromegaly, including treatment modalities, biochemical outcome, and comorbidities, with a particular focus on cancer and mortality.MethodsPertinent acromegaly-related variables were collected from 739 patients diagnosed since 1990. Data are presented across three decades (1990–1999, 2000–2009, and 2010–2021) based on the year of diagnosis or treatment initiation.ResultsAdenoma size and insulin-like growth factor I (IGF-I) levels at diagnosis did not differ significantly between study periods. The risk of being diagnosed with diabetes, heart disease, sleep apnea, joint disease, and osteoporosis increased from the 1990s to the later decades, while the mortality risk declined to nearly half. The risk of cancer did not significantly change. Treatment changed toward the use of more medical therapy, and fewer patients underwent repeat surgeries or pituitary irradiation. A statistically significant increase in the proportion of patients achieving IGF-I normalization within 3–5 years was observed over time (69%, 83%, and 88%). The proportion of patients with three or more deficient pituitary hormones decreased significantly over time.ConclusionModern medical treatment regimens of acromegaly as well as increased awareness and improved diagnostics for its comorbidities have led to better disease control, fewer patients with severe hypopituitarism, and declining mortality in the Danish cohort of acromegaly patients. The risk of cancer did not increase over the study period.
Drag reduction of Clark-Y hydrofoil by biomimetic fish scale structure under the condition of biomimetic jet
Authors: Yan Hao , Xie Tengzhou , Li Jian , Fan Jinchuan , Dai Xinyue 
Published: April 2024

Hydrofoil, as the basic shape of the fluid blade, is widely used in fluid transport and energy conversion. However, friction resistance and pressure differential resistance are generated in the hydrofoil flow process, resulting in substantial energy consumption and negatively affecting the economy. On this basis, we propose two drag-reducing structures based on Clark-Y hydrofoil. In the design process of the jet structure, we considered the bionic jet velocity, jet angle and jet structure position as the design parameters and obtained the optimal jet structure by using Taguchi method. Finally, the two schemes (Clark-Yori and Clark-Yopt) are numerically simulated using large eddy simulation. Results show that when Ujet = 1.44 m/s, θ = 3° and x = 18.6 mm, the jet structure can play a significant drag reduction effect. Compared with Clark-Yori, the drag coefficient of Clark-Yopt is reduced by 26.5%, and the lift drag ratio is increased by 16.4%. Compared with Clark-Yori, Clark-Yopt can reduce the wall shear stress of the leading edge of the hydrofoil, thereby diminishing the frictional resistance. Meanwhile, the jet structure can effectively balance the area of the low-pressure region on the suction side of the hydrofoil, significantly reducing the pressure differential resistance. Clark-Yopt can accelerate the vortex collapse that decreases turbulence intensity and turbulence resistance. Moreover, it can effectively block the near-wall reflux of hydrofoil and reduce the internal friction between the reflux and the main flow.