bluuebunny/crossref_metadata_2025_split huggingface dataset:
Clinico-epidemiological study of dermatological disorders in pediatric population at tertiary care centre
Authors: C Lalitha , Reddy Chandan Kumar , Prasad Anupama Manohar , Salahuddin Syed 
Published: February 2025

Children in India constitute a substantial portion of the population, with nearly half a billion children, about 40% of the total population. Skin diseases are prevalent among them, accounting for 30% of dermatologist and pediatrician visits and conditions vary widely across regions due to factors like poverty, malnutrition, hygiene, and climatic influences. Pediatric dermatology addresses unique challenges in managing skin diseases from infancy to adolescence, necessitating tailored approaches distinct from adult care. Understanding these variations is crucial for effective diagnosis and treatment, ensuring optimal childhood health outcomes.A hospital-based clinical descriptive study was conducted, involving 600 children under the age of 16, clinically diagnosed with skin diseases over a period of one and half year after ethical committee approval. In this study, 600 pediatric patients (316 males, 284 females; mean age 8.06 ± 5.10 years) were analyzed for dermatoses. The majority of patients were aged 11-16 years (36.33%). A total of 642 skin disorders were recorded, with infections and infestations being the most common (39.41%), followed by eczematous diseases (21.49%). Among infections, bacterial infections were most prevalent (36.76%), with impetigo being the most common bacterial infection (52.7%). Viral infections were led by verruca vulgaris (43.4%), while Tinea was the predominant fungal infection (58.49%). The study highlights significant variations in dermatoses across different age groups, with a higher incidence of bacterial infections in younger children and fungal and viral infections in older children. Pediatric dermatoses present varied challenges in diagnosis and treatment globally, affecting rural and urban populations differently. Our study categorized these conditions into fewer than eight groups, highlighting infections as most prevalent, followed by eczematous and pigmentary disorders. Disease distribution is influenced by age, gender, socioeconomic factors, family history, and seasonal variations. Effective strategies require enhancing public awareness, improving hygiene practices, and implementing targeted interventions based on regional epidemiology to reduce the burden and improve pediatric health outcomes.
Evaluation of lipid profile in young adults (18-50 years) with psoriasis vulgaris in Chennai
Authors: Kuberan Abinaya , MP Sankeerthana , Thomas Jayakar , Sharma Shea , K Gopalakrishnan 
Published: February 2025

Psoriasis is a chronic inflammatory and proliferative skin condition influenced by both genetic and environmental factors. Its typical manifestations include red, scaly, well-defined plaques that often appear on the extensor surfaces of the body and the scalp. The disease can vary significantly in terms of duration, frequency of flare-ups, and affected areas, and it often presents with various morphological variations.My study aims to primarily ascertain the frequency of lipid disturbances in patients with psoriasis vulgaris and their extent of derangement correlated with severity of psoriasis.After obtaining ethical committee clearance, and consent from patients, 130 psoriatic patients were studied. Their lipid profiles were investigated. PASI was assessed against derangements in fasting lipid profiles using statistical analysis ANOVA.Most common age group affected was between 26 to 35 years. 55% males and 45% females were affected. NCEP ATP III guidelines was followed for fasting lipid evaluation. 19% cases had elevated triglycerides levels. 65% had elevated HDL cholesterol levels. 33% cases had elevated serum cholesterol levels.45% cases had elevated LDL, 28% had elevated VLDL. 79% had elevated waist circumference. 3% had increased albumin levels, 45% had increased serum globulin levels, 0.8% had increased albumin globulin ratio, 8% had increased total bilirubin levels, 3% had increased direct bilirubin levels, 7% had increased serum AST, 1.5% had increased serum alkaline phosphatase and 8% had increased Gamma glutamyl transferase.After statistically evaluating PASI with cholesterol levels and waist circumference, PASI and Cholesterol & Waist circumference was statistically significant with P values showing 0.01 and 0.021 respectively. No statistical difference was noted between PASI and Liver function test values. Hence, PASI and cholesterol levels and waist circumference can be taken as an indicator to assess the severity of psoriasis and cardiac involvement by periodically screening the patient .
Evaluation of dermatoses in pediatric age group (3-15 yrs) in accordance with seasonal variation
Authors: T U Pooja , Jayakrishnan Roma , Thomas Jayakar , Kunjaram Gopalakrishnan 
Published: February 2025

This study aimed to evaluate pediatric dermatoses based on clinical diagnosis and seasonal variation at a tertiary care hospital in Chennai. Informed consent was obtained, and histories recorded; diagnoses were based on physical examination. It included 271 patients aged 3–15 years, with a mean age of 7.93 ± 3.52 years (range: 3–15) and a median of 8 years (IQR: 5–10). The highest prevalence was in children aged 3–6 years, with a balanced gender distribution. Cases peaked during monsoon and summer. Infections, especially viral, were most common, with scabies being the leading diagnosis. Patients aged 3-15 years who visited the dermatology OPD were selected. Informed consent was obtained from parents or guardians, and their medical, family, and treatment histories were recorded. A thorough physical examination was conducted to reach a diagnosis.The study included 271 patients, mostly younger children (mean age: 7.93 ± 3.52 years; range: 3–15; median: 8 years; IQR: 5–10).Participants included 51.5% males and 48.5% females, showing a balanced gender distribution. Distribution of participants by season, cases were highest in monsoon (32.6%) and summer (31.9%), with fewer in winter (24.4%) and post-monsoon (11.1%). Distribution of participants by disease group shows, Viral infections as the most common (21.1%), followed by parasitic infestations (13.0%), eczema (11.1%), and fungal infections (10.0%), with other disorders also observed.The study found higher cases of pediatric dermatoses in children aged 3-6 years, with a balanced gender distribution. More cases occurred in monsoon and summer. Viral infections were most common, with scabies as the leading diagnosis, followed by chicken pox, insect bite hypersensitivity, atopic dermatitis, hand-foot-mouth disease, and verruca vulgaris.
Unlocking the healing potential: Agada tantra principles in pyoderma gangrenosum management
Authors: Savalagimath Mahesh P , Walia Arpit , Devaraddiyavar Vinuta H 
Published: February 2025

Due to their rising prevalence and growing awareness of the associated morbidity and socioeconomic burden, chronic ulcers, defined by their inability to heal within a reasonable amount of time, have become a more significant clinical issue. In Ayurveda, Agada Tantra principles provide a comprehensive approach to treating chronic wounds. We present a case report of a 60-year-old female patient with a non-healing ulcer on the lateral aspect of her right leg that had been present for one year and associated with Itching and burning sensation, as well as serosanguineous discharge from the wound.Hence Pyoderma gangrenosum was successfully managed using Ayurveda intervention, highlighting the potential of Agadas in managing chronic ulcers.
Geometric morphometric analysis of palatal form in patients with maxillary anterior teeth impaction-A systematic review
Authors: Rana Shailendra Singh , Rajagopalan Anjana , Lal Babu , Chaudhari Prabhat Kumar 
Published: February 2025

Morphometrics is a rising technology being employed for describing biological structures in terms of quantifying their shape and form. This review explores maxillary palatal vault shape and arch dimensions which are proposed to have a role in the aetiology of maxillary buccal and canine impactions. To analyse the morphological variations in palatal shape in subjects with maxillary anterior teeth impaction using Geometric Morphometric Analysis. Two independent reviewers searched six databases (PubMed, Web of Science, Embase, Google Scholar, Scopus, and Open Grey). The searches were carried out in November 2023 with no restrictions on publication date. Observational studies and Randomised controlled trials (Study design) were included wherein the morphological variations in palatal shape (outcome) in subjects with maxillary anterior teeth impaction (population) studied using Geometric Morphometric Analysis (intervention). The Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) guidelines were applied, and the protocol was registered in PROSPERO (CRD42023449757). The risk of bias was determined using the Anatomical Quality Assessment (AQUA) tool. Patients with unilateral or bilateral buccal displaced permanent canine showed a vertical extension and a horizontal compression in the lateral area of the palate. Palatal canine impactions had minimal relationship with palatal shape and morphology. Morphometric variations of the palatal vault can be considered a factor in determining the probability of maxillary anterior teeth impactions.
Comparative evaluation of sequential maxillary molar distalization utilizing clear aligners in combination with micro-implants and Class II elastics for reinforcing the anchorage- A finite element model study
Authors: Trambadia Shikha , Gadhiya Nitin , Khamatkar Aparna , Sawant Veera , Shroff Keval , Jadhav Pranita 
Published: February 2025

This study aims to perform a comparative evaluation of sequential maxillary molar distalization using clear aligners in combination with micro-implants and Class II elastics for reinforcing anchorage. The goal is to assess the biomechanical effectiveness and outcomes of these methods in achieving distalization without unwanted tooth movements.A finite element model (FEM) study was conducted using the CBCT data of a 21-year-old female patient with Class II malocclusion. The 3D model of the maxilla and maxillary dentition was created and meshed for simulation. Five sub-models were developed to represent different treatment scenarios: clear aligners alone (control), aligners with Class II elastics using buttons or precision cuts, and aligners with micro-implants combined with elastics. Each model simulated sequential molar distalization with static loading forces. Displacement and stress responses were analyzed to determine the effectiveness and control of tooth movements.The FEM simulations revealed that the use of clear aligners with Class II elastics and micro-implants enhanced molar distalization efficiency while minimizing mesial displacement of anchorage teeth. Models with precision cuts and micro-implants showed superior anchorage control, reducing unwanted tipping and rotation. The greatest displacement was observed in models using precision cuts with Class II elastics, while the least displacement occurred in the control models.The study concluded that Class II elastics provide superior control over molar movement compared to micro-implants when used with clear aligners for sequential maxillary molar distalization. Precision cuts on aligners offer better anchorage reinforcement than buttons.
Radiographic assessment of apical root resorption in the mandibular molars following the usage of resin bite turbos in orthodontic patients– A retrospective study
Authors: Maddalena Marrapodi Maria , Raju Rebekah , Navaneethan Ramasamy , Subramanian Aravind Kumar , Ramalingam Karthikeyan , Uzunçıbuk Hande , Russo Diana , Cicciù Marco , Minervini Giuseppe 
Published: February 2025

Orthodontic treatment involves the use of bite turbos that are frequently utilized in orthodontic therapy to disocclude the lower and upper teeth to achieve adequate alignment and leveling. This occurs due to excessive intrusive forces which led to resorption of roots. This study aimed to quantify the amount of apical root resorption in molar region caused by bite turbos using orthopantomograms (OPGs). The study involved 30 OPGs pertaining to orthodontic patients, each before and after orthodontic therapy. The study group involved patients for whom bite turbos were placed in the mandibular molar region for a minimum of 4 months during treatment. The control group involved the OPGs of patients without the use of bite turbos. The molar root and crown lengths were assessed using modified Lind approach. Root crown ratio was measured for each molar, and the relative root crown (rRCR) ratio was determined.The placement of biting turbos on the mandibular molars resulted in a decline in rRCR, which suggested a decrease in the root length. The ratios for the study and control groups differed significantly (p=0.014). Additionally, significant variations were detected between the study groups' pre and post ratios based on statistical analysis (p=0.00 ).C Bite turbos can be considered as a factor that could cause root resorption if used for a prolonged period during orthodontic therapy.
Acceptance or rejection of the COVID-19 Vaccine: A cross-sectional study among Orthodontists
Authors: Minervini Giuseppe , Kadhom Zainab Mousa , Faleh Albo Hassan Alaa , Ali Abdul Ameer Suha , Nahidh Mohammed , Maddalena Marrapodi Maria , Cicciù Marco 
Published: February 2025

Close contact with the infected patient is one reason for the spread of infection. COVID-19 can easily infect orthodontists; it may be found in saliva droplets during the removal or insertion of the orthodontic fixed appliance components or even during the removal of the removable appliance. This study aims to assess the acceptance or rejection of the COVID-19 vaccine among Iraqi orthodontists. A web-based cross-sectional survey among orthodontists in Iraq was conducted. Thirteen pre-structured questions were sent in a Google Form via their WhatsApp and Telegram groups. There were 123 orthodontists participating in this survey. The majority of the participants (96.75%) were aware of COVID-19, and 62.60% suggested that coronavirus poses a significant risk. Orthodontists who took the vaccine accounted for 93.50%; among them, those who preferred the Pfizer vaccine accounted for 57.39%. The side effects associated with the vaccine were the leading reasons for vaccine refusal. Although there is a high level of awareness about COVID-19 viruses among orthodontists, some abstained from the vaccine because of fear. The acceptance of COVID-19 vaccines and the number of participants who got the vaccine were high to achieve precise infection control in orthodontic clinics and decrease viral infection spread.
Assessment of cortical plate thickness and bone density of mandibular symphyseal region in subjects having skeletal Class III malocclusion with different facial types – A CBCT study
Authors: Churiwal Devanshi , Bhagchandani Jitendra , Vashishta Vaibhav , Singh Ayushi , Raj Stuti , Rastogi Tushant 
Published: February 2025

The study used CBCT to analyze mandibular symphyseal bone thickness and density in Skeletal Class III subjects with different vertical facial patterns. It found higher cortical bone thickness in Normodivergent and higher bone density in Hypodivergent subjects, emphasizing the importance of careful orthodontic treatment to avoid complications related to reduced bone density and cortical thickness. CBCT images of 30 skeletal Class III subjects were evaluated. Class III subjects were divided by mandibular plane angle: Hyperdivergent (SN–MP &#62; 34o), Normodivergent (SN–MP – 32o), and Hypodivergent (SN–MP &#60; 30o) groups. Buccolingual cortical bone thickness and bone density was measured using CBCT images of mandibular incisors at alveolar crest and 3, 6 and 9 mm apical levels. Shapiro Wilk test, Bonferroni post-hoc test, and Pearson correlation analysis were used for statistical significance. The mean cortical bone thickness of the mandibular symphyseal region was highest in Normodivergent subjects (Group I) and lowest in Hyperdivergent subjects (Group III). Group II subjects with a Hypodivergent growth pattern had the highest mean bone density, with the lowest reported in Normodivergent subjects on the labial side and Hyperdivergent subjects on the lingual side. However, differences in bone density among groups were statistically insignificant. Careful orthodontic treatment in Skeletal Class III malocclusion, especially with Hyper-divergent facial types, is crucial to prevent root issues due to reduced bone density. Bracket adjustments are essential for optimal outcomes by ensuring proper root placement within cancellous bone.
Comparison of linear dimensional changes of mandibular symphyseal morphology in patients of various age groups with different growth patterns - A retrospective CBCT study
Authors: Pandian Srirengalakshmi Muthuswamy , Setvaji Nisshitha Rao 
Published: February 2025

Mandibular symphyseal morphology is a significant aspect in orthodontic treatment planning. The current research aimed at comparing the linear dimensional variations of the mandibular symphysis seen in various age groups with different growth patterns using CBCT.Ninety CBCTs were segregated into three groups based on their growth patterns as horizontal (HGP), average (AGP), and vertical (VGP). Each group was additionally categorised into age-based subgroups such as Pre-adolescent (&#60;13 years), Adolescent (13-20 years), and Adult (&#62;20 years). The symphyseal height and widths were measured along the midline and the lateral aspects. One-way analysis of variance (ANOVA) and the Bonferroni post hoc test were employed. The right and left sides were differentiated by applying the Independent-t test. Kendall Tau’s b correlation tests were performed to determine the relation between the measured parameters and age as well as the parameters with the growth patterns.In the pre-adolescent age group, a significant increase in symphyseal height and upper width was seen along the midline (P &#60; 0.05). In the adolescent age, a significant difference was observed in the height and upper width on the lateral aspects (P &#60; 0.05). In the adult age group, a significant increase in the lower width along the midline and lateral aspects was seen (P &#60; 0.05). Patients with HGP showed increased width whereas VGP showed increased height in all age groups.The quantitative dimensions of the symphysis varied with increasing age in different growth patterns which is essential for preoperative surgical planning.
A Comparative evaluation of the Shear bond strength of brackets bonded to pre-treated demineralised enamel treated with two different remineralising agents – An In-vitro study
Authors: Revathi P. , Shaik Shafeen Naqheeb , Mallavarapu Kalyani , Lanka Devikanth , Dokku Aruna , Pichai Saravanan 
Published: February 2025

Remineralising agents are suggested on sound enamel and on demineralised enamel during fixed appliance therapy as they increase the risk of enamel demineralization; but their influence on bond strength is questionable. Toothmin has been recently introduced and showed promising results in preventing demineralization and promoting remineralization similar to CPP-ACP.Therefore, the rationale of doing this study is to evaluate Toothmin efficacy on shear bond strength (SBS) of pre-treated demineralized enamel. To measure the SBS of brackets bonded to pretreated demineralised enamel treated with Toothmin and CPP-ACP. Settings and Design: Teeth were divided into four groups prior to bonding. Group I with No enamel pre-treatment, Group II, demineralized enamel, Group III, CPP-ACP was applied on demineralized enamel whereas in Group IV, Tooth min was applied on demineralised enamel. Intact enamel group, demineralised group and remineralised groups were evaluated for SBS and (Adhesive Remnant Index ) ARI scores.Statistical analysis: Data were analyzed using IBM SPSS version 20 software and subjedted to one way analysis of variance with Tukey’s post hoc tests. Toothmin group had highest mean SBS (10.37±3.08) followed by CPP-ACP (9.6±2.43), control (8.67±2.31), and the demineralization (2.42±1.21) groups. Highest mean ARI scores were observed in Toothmin group (2.33±0.48) and the least in the demineralization group (0.4±0.507).Demineralization of enamel significantly reduces the SBS of orthodontic brackets. Remineralization of enamel with Toothmin or CPP-ACP after demineralisation improved bond strength. Highest mean ARI scores were observed in Toothmin group and lowest in demineralized group.
Perceptions of patients regarding the cost of orthodontic treatment: Questionnaire based study
Authors: Chugh Tina , Ahluwalia Rajiv , Mathew Mary , Mailk Robin , Katara Pradhumn 
Published: February 2025

Ensuring affordable orthodontic treatment is essential for promoting equitable access to dental care, emphasizing the significance of justice in addressing socio-economic disparities and fostering equal opportunities for individuals seeking orthodontic interventions. This study aims to investigate the perceptions of patients regarding the cost of orthodontic treatment and the factors influencing their views on affordability. A semi-structured questionnaire was distributed to 116 participants undergoing orthodontic treatment to gather data on demographic information, personal experiences with orthodontic treatment, and attitudes toward the perceived cost of such treatment. The questionnaire was developed with input from orthodontic professionals and validated through pilot testing. Descriptive statistics including frequencies and percentages were calculated for all quantitative and categorical variables. Bivariate inferential analyses using chi-square tests were conducted to assess associations between categorical variables. Statistical significance was determined using a p-value cut-off of 0.05. P-values below 0.05 were considered statistically significant. The study showed that 96% of the participants were satisfied with the treatment. 94.0% felt that the treatment cost was justified by the duration of the treatment and the type of appliance. However, 49.1% of participants still felt the need for cost reduction. Patients with higher monthly income felt less need for cost reduction (p value &#60; 0.001). There was an association between monthly income and the payment plan (p - 0.045), and between education and treatment satisfaction. (p-value = 0.018) This questionnaire-based study sheds light on the diverse perceptions surrounding the cost of orthodontic treatment. Understanding these perspectives is crucial for healthcare professionals, policymakers, and stakeholders to develop strategies that enhance accessibility and affordability while addressing the broader implications of orthodontic care on individuals' well-being.