bluuebunny/crossref_metadata_2025_split huggingface dataset:
L'en-deçà et l'au-delà du droit.Penser la légitimité en droit, de la normativité juridique à la fonction sociale du droit
Authors: Husson-Rochcongar Céline 
Published: March 2024

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Émergeant d’une jungle conceptuelle, la légitimité constitue une passerelle entre le politique et le juridique. Au cœur du processus par lequel le droit transforme une réalité politique en réalité juridique, elle se fait révélateur la matière sociale qui forme tant l’en-deçà que l’au-delà du droit. Par un double mouvement du droit aux sciences sociales et des sciences sociales au droit, penser la légitimité éclaire donc la fonction sociale du droit, la normativité juridique étant vecteur d’institutionnalisation du monde social.
International audience
Analyse réflexive des a priori théoriques et épistémologiques d'une posture de recherche engagée
Authors: Dufourt Pénélope 
Published: March 2024

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La lecture d'une thèse ne permet pas toujours de saisir le processus intellectuel qui a été engagé par son auteur.e. OEuvrer à un exercice réflexif quant à sa démarche de recherche est ainsi l'occasion de préciser les prémisses et postulats théoriques sous-jacents à son propre travail. Cet article sera l'occasion d'opérer ce mouvement réflexif à partir d'une analyse des présupposés philosophiques inhérents d'une recherche critique et interdisciplinaire sur le droit à l'éducation aux droits de l'Homme.
International audience
Homologation des transactions : le doute ne profite pas aux libéralités
Authors: Diemer Marie-Odile 
Published: March 2024

Soumission à Epi-revel
La procédure d'homologation des transactions est suffisamment rare et exceptionnelle pour être signalée d'autant quand le juge la confronte à la prohibition des libéralités et au contentieux de la responsabilité. Un exemple en est donné dans ce jugement du tribunal administratif.
International audience
Mathematical Modelling of COVID-19 with Vaccination, Quarantine and Non-Pharmaceutical Interventions
Authors: Abdulrahman Mustapha  , Samuel Musa  , Musa Abdullahi  , Abdulmumini Husseini  
Published: March 2024

This study formulated and analyzed a deterministic mathematical model of ten compartments for the transmission dynamics of COVID-19 infection using a system of non-linear ordinary differential equations. The system has disease-free and endemic equilibrium points. The basic reproduction number was obtained using the next-generation matrix method and the stability of the equilibrium points were analyzed. From the qualitative analysis, the disease-free equilibrium point is both locally and globally asymptotically stable. Finally, numerical simulations of the model were carried out using MATLAB R2021a. Based on the result obtained, it was concluded that the implementation of vaccination, non-pharmaceutical intervention as well as contact tracing and quarantine can lead to effective control or elimination of the COVID-19 pandemic. And hence, we recommend that the responsible agencies should create a way of enlightening the public on the need of being vaccinated for COVID-19 so as to prevent themselves from getting infected; also, adequate and effective implementation of vaccination and non-pharmaceutical interventions is required in order to prevent or curtail the COVID-19 infection completely.
COVID-19, Non-pharmaceutical intervention, Quarantine, Stability analysis, Vaccination
A Nonlinear Mathematical Model for the Effect of Diabetes Population on a Community
Authors: Kwaghkor Lubem M. , Adamu Samuel , Abdullahi Mohammed , Mohammed Suleiman 
Published: March 2024

This work presents a compartmental-based mathematical model of susceptible, diabetes without complications, diabetes with minor and major complications to study the effect of diabetes population on the population dynamics of a community. The model is a system of four nonlinear differential equations of first order. The solution of the model was found to exist and is positive by positivity analysis using a contradiction method. The diabetes-free and the diabetes-endemic equilibrium points were also found to be locally asymptotically stable using the Routh-Hurwitz Stability Criterion for a degree n-polynomial. The numerical simulation of the model was carried out using various scenarios and the results show that diabetes population in a community has great effect on the population dynamics of the community either positively or negatively. The results here represent a real-life scenario thereby making the proposed model realistic.

Diabetes, Mathematical Model, Simulation, Stability
Mathematical Analysis of Hepatitis B Virus Model with Interventions in Taraba State, Nigeria
Authors: Bashir Umar S. , Umar Ahmed 
Published: March 2024

A new version of a mathematical model for the dynamics of the Hepatitis B Virus (HBV) with a combination of three interventions was proposed. The primary focus of the study was to combine treatment, vaccination, and media campaigns as control strategies for reducing the spread of HBV. The study established the existence of a disease-free steady state of the model. The disease-free steady state was both locally and globally asymptotically stable. Additionally, the numerical results revealed that combining the three interventions is the best control strategy for curbing the menace of HBV. The study suggested that more effective campaign efforts should be supplemented with other major control strategies to get substantial paybacks in curbing the menace of HBV.
Hepatitis B Virus (HBV), Intervention Stability, Steady-State
The impacts of higher education institutions on sustainable development: A field Study
Authors: Alkhaldy Ayman 
Published: March 2024

The current study sought to identify the role of higher education institutions in spreading a culture of environmental sustainability. The study used a social survey with a random sample of 30 male and female students who were selected non-randomly. The results of the study showed that university youth contribute to spreading the culture of environmental sustainability through university activities, and the university also spreads the culture of the environment by providing books and publications related to environmental preservation. On the other hand, the study found that curricula and programs are not linked to what is happening in the local environment. Some limitations of the research also emerged, such as the lack of modern curricula whose topics help spread the culture of environmental sustainability.

سعت الدراسة الحالية إلى التعرف على دور مؤسسات التعليم العالي في نشر ثقافة الاستدامة البيئية. استخدمت الدراسة المسح الاجتماعي من خلال عينة عشوائية مقدارها 30 طالباً وطالبة تم اختيارهم بالطريقة غير العشوائية. أظهرت نتائج الدراسة أن الشباب الجامعي يساهم في نشر ثقافة الاستدامة البيئة من خلال الانشطة الجامعية، وكذلك تقوم الجامعة في نشر ثقافة البيئة من خلال توفير الكتب والمنشورات المتعلقة بالمحافظة على البيئة. في المقابل وجدت الدراسة أن عدم ربط المناهج والمقررات الدراسية بما يحدث في البيئة المحلية، كما برزت بعض المحددات للبحث والتي تتمثل في عدم وجود مناهج حديثة تساعد موضوعاتها في نشر ثقافة الاستدامة البيئية.
Effect of Application of Secondary Nutrients on Growth, Yield and Quality of Maize (Zea mays L.)
Authors: Srinivas P. , Sannathimmappa H. G. , Sridhara S. , Salimath Sarvajna B. , Kalleshwaraswamy C. M. 
Published: March 2024

A field experiment was conducted during Rabi 2022 at the Agriculture and Horticulture Research Station, Honnavile, Shivamogga on sandy clay loam soil to study the response of maize to secondary nutrients application. The experiment was laid out in Randomized Complete Block Design (RCBD) and consisted of nine treatments replicated three times. The treatments consisted of package of practice (POP) (T1), POP + soil application of two levels of calcium, i.e., 25 and 50 kg ha-1 through lime (T2 and T3), dolomite (T4 and T5, which amount to 15.02 and 30.04 kg ha-1 of magnesium, respectively) and gypsum (T6 and T7, which amount to 19.96 and 39.91 kg ha-1 of sulphur, respectively). Treatments T8 and T9 consisted of POP + combined application of all three secondary nutrients through lime, magnesium sulphate and bentonite sulphur to meet the same level of nutrient as treatments T2 to T7. Among the treatments, application of POP + calcium @ 25 kg ha-1 through lime + 15.02 kg ha-1 of Mg + 19.6 kg ha-1 of S (T8) showed significantly higher values for growth parameters viz., plant height (196.65 cm), leaf area (4804.70 cm2), leaf area index (5.55) total dry matter (273.80 g plant-1) and yield parameters viz., cob length (16.93 cm), number of grains cob-1 (511.08), kernel yield (6772 kg ha-1) and stover yield (8221 kg ha-1). Similarly the same treatment recorded significantly higher grain protein content (8.99%) compared to other treatments. However the test weight, harvest index and oil content of maize remained unaffected due the applied secondary nutrients.
Evaluation of Yield Advantages, Competitiveness and Economic Benefits of Pigeonpea (Cajanus cajan L.) Based Intercropping Systems Under Different Date of Sowing
Authors: Pawar G.R. , Waghmare P. K. , Bhadre C.K. , Gokhale D.N. 
Published: March 2024

The experiment conducted at the Department of Agronomy farm, VNMKV., Parbhani (MH), during the kharif seasons of 2016-2017 and 2017-2018, integrates key agro-environmental factors. The utilization of deep black (vertisol) soil with good drainage replicates prevalent soil conditions in the region, ensuring the relevance and applicability of the findings to tropical environments of Latin America [20,21]. The implementation of a split plot design with two replications, considering four sowing dates and seven cropping systems, enhances the experimental robustness, facilitating a comprehensive evaluation of the interactions between timing and cropping systems [6,22].The study's findings highlight the significance of sowing dates in maximizing pigeonpea equivalent yield and net monetary returns, with sowing within a week period after the regular commencement of the monsoon (D1) demonstrating superior performance. Furthermore, the pigeonpea + soybean intercropping system emerges as the most favorable [50], indicating its potential for enhancing agricultural productivity and economic returns in the region [17,19]. The study's insights into the competitiveness and economic benefits of different intercropping systems provide valuable guidance for agronomic management practices in tropical environments [50]. By identifying the superior performance of certain cropping systems, such as pigeonpea + soybean, and the influence of sowing dates on yield outcomes [51,45], the study informs farmers and agricultural practitioners on optimal strategies for maximizing productivity and profitability in pigeonpea cultivation [29,30].
The observed behavior of component crops within intercropping systems underscores the complexity of crop interactions and highlights the need for tailored management approaches. The dominance of the niger crop in intercropping systems over the pigeonpea base crop emphasizes the importance of understanding crop dynamics for optimizing yield outcomes [5,18]. Additionally, the study's evaluation of different sowing dates contributes to enhancing climate resilience [14] in agricultural systems by identifying optimal timing strategies for mitigating climate variability effects on crop performance [7,37,13].
Inside and outside the mind: The effects of age, organization, and access to external sources on retrieval of life events
Authors: Lipman Paula Darby , Caplan Leslie J. , Schooler Carmi , Lee Jason S. 
Published: June 2007

AbstractOlder and middle‐aged adults recorded autobiographical events on one of two forms of a Personal History Calendar, organized either by year‐of‐occurrence or by life event category. In Experiment 1, calendars were completed in three stages. In Stage 1, subjects completed the calendar from memory (half were told to expect Stage 2). In Stage 2, each subject reviewed Stage 1 responses with his/her spouse. In Stage 3, subjects could consult external sources. The Event Calendar yielded the most complete Stage 1 recall only for the older group. The Year Calendar generally yielded the greatest number of events, but only when members of a couple did not expect Stage 2. In Experiment 2, subjects completed the calendars in one stage, during which they had access to external sources. The Year Calendar elicited more events than the Event Calendar, but only for older subjects. The results are discussed in terms of retrieval processes in autobiographical memory, and implicatons for survey‐based research.
Motivational determinants of reading comprehension: A comparison of French, Caucasian–American, and African–American adolescents
Authors: Kurtz‐Costes Beth , Ehrlich Marie‐France , McCall Rona J. , Loridant Catherine 
Published: June 2007

AbstractThe relationships between adolescents' reading comprehension and their metacognitive knowledge and self‐system beliefs were studied in three groups of subjects: French nationals, Caucasian Americans, and African Americans. Subjects were tested on measures of reading comprehension, metacognitive knowledge about reading processes, attributional beliefs, and academic self‐concept. Correlation and regression analyses indicated cultural differences in the predictors of reading comprehension among the three groups. For French and Caucasian Americans, reading comprehension scores were related to metacognitive knowledge, academic self‐concept, and attributions of success to ability. However, metacognition and motivational beliefs were mostly unrelated to comprehension performance for African Americans. Results are discussed in terms of verification of a model of motivational influences on performance, of cultural and ethnic group differences in beliefs, and the implications for generalizability of research results.
Convergence analysis of the quasi‐OBE algorithm and related performance issues
Authors: Deller J. R. , Gollamudi S. , Nagaraj S. , Joachim D. , Huang Y. F. 
Published: June 2007

Abstract‘Quasi‐OBE’ (QOBE) is an adaptive set identification and filtering algorithm which is based on the principles of optimal bounding ellipsoid processing, but which has other geometric and classic least‐squares interpretations which greatly enhance its application potential. In particular, because of its unusual optimization criterion, the ellipsoidal membership set associated with QOBE is more likely to retain (i.e. to move in the parameter space with) the system model's ‘true parameters, ’ sayθ*, when those parameters are time varying. Moreover, in the unlikely event thatθ*moves outside the set, the integrity of the point‐set estimation remains intact, and the estimator provably converges under known conditions. The consistency of the set estimation can be restored at any time using typical ‘rescue procedures’ if desired. Understanding convergence performance is very critical to successful QOBE application. Convergence analysis of both the central point estimate and measures of the hyperellipsoidal membership set is presented. The main results give conditions for point estimate convergence, and show that set convergence to a point is not possible. Implications of these convergence results for practical application are discussed. Copyright © 2007 John Wiley & Sons, Ltd.
Titration and Assignment of Residues that Regulate the Enantioselectivity of Phenylacetone Monooxygenase
Authors: Zambianchi Francesca , Fraaije Marco W. , Carrea Giacomo , de Gonzalo Gonzalo , Rodríguez Cristina , Gotor Vicente , Ottolina Gianluca 
Published: June 2007

AbstractPhenylacetone monooxygense (PAMO) from Thermobifida fusca was employed for the asymmetric oxidation of thioanisole (sulfooxidation) and of racemic 2‐phenylpropionaldehyde (Baeyer–Villiger oxidation). A pH dependence of enantioselectivity was observed in both cases. Two different residues, with pKa values of 7.8±0.2 and 9.2±0.2, appeared to be responsible for the pH effects on PAMO enantioselectivity. The protonation of Arg337 and the FAD:C4a‐hydroperoxide/FAD:C4a‐peroxide equilibrium were identified as the major factors responsible for the fine‐tuning of PAMO enantioselectivity in Baeyer–Villiger oxidation and sulfooxidation, respectively.
Enzymatic Preparation of Novel Aminoalkylpyridines using Lipases in Organic Solvents
Authors: Torre Oliver , Busto Eduardo , Gotor‐Fernández Vicente , Gotor Vicente 
Published: June 2007

AbstractA wide range of novel, enantiomerically pure 4‐chloro(amino)pyridine derivatives has been synthesised through a chemoenzymatic approach, Candida antarctica lipase B (CAL‐B) and Pseudomonas cepacia lipase (PSL) being found to be excellent biocatalysts for the preparation of new and interesting amines and amides in enantiomerically pure form through enzymatic aminolysis reactions. A study of the enzymatic reactivity of CAL‐B and PSL has been done in the resolution of a library of amine structures in an attempt to rationalise the experimental results obtained in their enzymatic kinetic resolution mediated by lipases.
Laccase‐Mediated Oxidation of Totarol
Authors: Ncanana Sandile , Baratto Lara , Roncaglia Lucia , Riva Sergio , Burton Stephanie G 
Published: June 2007

AbstractIn this study, novel dimers of the biologically active phenolic compound totarol were synthesized using the phenol oxidase enzyme laccase, obtained from Trametes pusbescens, in organic solvent medium. Two dimeric products, linked either by carbon‐carbon or by carbon‐oxygen bonds, were isolated and characterized. The effect of changes in various parameters such as solvent, temperature, pH and buffer concentration on the conversion of totarol by laccase was investigated. The nature of the organic solvent, in particular, was found to affect the nature and the ratio of the products obtained.
Preparation of an Amino Acid Intermediate for the Dipeptidyl Peptidase IV Inhibitor, Saxagliptin, using a Modified Phenylalanine Dehydrogenase
Authors: Hanson Ronald L. , Goldberg Steven L. , Brzozowski David B. , Tully Thomas P. , Cazzulino Dana , Parker William L. , Lyngberg Olav K. , Vu Truc C. , Wong Michael K. , Patel Ramesh N. 
Published: June 2007

AbstractThe non‐proteinogenic amino acid 2‐(3‐hydroxy‐1‐adamantyl)‐(2S)‐aminoethanoic acid [2, (S)‐3‐hydroxyadamantylglycine], is a key intermediate required for the synthesis of Saxagliptin, a dipeptidyl peptidase IV inhibitor under development for treatment of type 2 diabetes mellitus. Keto acid 2‐(3‐hydroxy‐1‐adamantyl)‐2‐oxoethanoic acid (1) was converted to (S)‐3‐hydroxyadamantylglycine by reductive amination using a phenylalanine dehydrogenase from Thermoactinomyces intermedius expressed in a modified form in Pichia pastoris or Escherichia coli. NAD (nicotinamide adenine dinucleotide) produced during the reaction was recycled to NADH (reduced form of nicotinamide adenine dinucleotide) using formate dehydrogenase. Pichia pastoris produces an endogenous formate dehydrogenase when grown on methanol, and the corresponding gene was cloned and expressed in E. coli. The modified phenylalanine dehydrogenase contains two amino acid changes at the C‐terminus and a 12‐amino acid extension of the C‐terminus. The modified enzyme is more effective with keto acid 1 than the wild‐type enzyme, but less effective with the natural substrate, phenylpyruvate. Production of multi‐kg batches was originally carried out with extracts of Pichia pastoris expressing the modified phenylalanine dehydrogenase from Thermoactinomyces intermedius and endogenous formate dehydrogenase, and further scaled up using a preparation of the two enzymes expressed in E. coli.
Glycosyl Azides – An Alternative Way to Disaccharides
Authors: Bojarová Pavla , Petrásková Lucie , Ferrandi Erica Elisa , Monti Daniela , Pelantová Helena , Kuzma Marek , Simerská Pavla , Křen Vladimír 
Published: June 2007

AbstractGlycosyl azides are shown to be efficient donors for β‐galactosidases, β‐glucosidases and α‐mannosidases. Only α‐galactosidases do not cleave the respective glycosyl azide 1 and, moreover, they exhibit competitive inhibition (especially α‐galactosidase from Talaromyces flavus). High water solubility and ready synthesis of glycosyl azides enable transglycosylation reactions even with difficult acceptors like N‐acetyl‐D‐mannosamine in good yields. The versatility of glycosyl azides was demonstrated in the synthesis of five disaccharides – two of them are described for the first time. All the reactions were highly regioselective, yielding β(1→6) isomers. β‐Galactosidase from E. coli proved to have the best synthetic capabilities. The present study shows that glycosyl azides are a valuable alternative to common p‐nitrophenyl glycoside donors and in many synthetic reactions.
Nitrilase‐Catalyzed Enantioselective Synthesis of Pyrrolidine‐ and Piperidinecarboxylic Acids
Authors: Winkler Margit , Meischler Dorith , Klempier Norbert 
Published: June 2007

AbstractThe enantioselective synthesis of the non‐proteinogenic amino acids β‐proline and nipecotic acids from their readily available nitriles is achieved in high enantiomeric excess by commercially available nitrilases. The presented procedure comprises not more than 4 steps, thus considerably reducing the multiple steps generally required. Amide formation is also observed for specific heterocyclic nitriles.
Chemo‐Enzymatic Dynamic Kinetic Resolution of Amino Acid Thioesters
Authors: Arosio Dario , Caligiuri Antonio , D'Arrigo Paola , Pedrocchi‐Fantoni Giuseppe , Rossi Cristina , Saraceno Caterina , Servi Stefano , Tessaro Davide 
Published: June 2007

AbstractThe L‐forms of racemic‐N‐protected‐β,γ‐unsaturated α‐amino acid thioesters were found to be substrates for the subtilisin‐catalysed hydrolysis to the corresponding acids. The D‐enantiomer was continuously racemised in the presence of an organic base. The combined reactions in a biphasic system allowed the deracemisation of the amino acid derivatives based on a dynamic kinetic resolution. Excellent yields and enantioselectivities were achieved.
Synthesis of Aromatic 1,2‐Amino Alcohols Utilizing a Bienzymatic Dynamic Kinetic Asymmetric Transformation
Authors: Steinreiber Johannes , Schürmann Martin , van Assema Friso , Wolberg Michael , Fesko Kateryna , Reisinger Christoph , Mink Daniel , Griengl Herfried 
Published: June 2007

AbstractThe applicability of the recent published bienzymatic protocol for the synthesis of (R)‐2‐amino‐1‐phenylethanol was tested using L‐threonine aldolase from Pseudomonas putida and l‐tyrosine decarboxylase from either Enterococcus faecalis (Efa) or two genes from Enterococcus faecium (Efi1, Efi2). In all 21 benzaldehyde derivatives were applied for an initial TLC screening. On a small scale, octopamine and noradrenaline were obtained as (S)‐enantiomers using Efi1. Three protocols were up‐scaled yielding enantioenriched (S)‐octopamine (yield 99 %, ee 81 %), (R)‐2‐amino‐1‐phenylethanol (yield 61 %, ee 62 %) and (S)‐noradrenaline (yield 76 %, ee 79 %).