bluuebunny/crossref_metadata_2025_split huggingface dataset:
Real‐time assessment on health state for bearing based on parallel encoder‐decoder observer
Authors: Li Kunpeng , Mi Jinhua , Wang Zhiguo , Yin Shengjie , Bai Libing , Qiu Gen 
Published: March 2024

AbstractBearings are foundational supporting components in diverse mechanical systems, essential for the reliable operation of these systems through real‐time monitoring and precise health state assessment. However, vibration signals from bearings in practical equipment often contain excessive noise and redundant information, complicating health state assessment. To address this challenge, this paper proposes a neural network‐based method named parallel encoder‐decoder (PED). This method features a parallel architecture that combines the long short‐term memory network and the temporal convolutional network for the encoder, along with a self‐attention module for the decoder. PED is adept at learning the temporal representations hidden in original signals and filtering vibration signals to remove noise and redundant information. Additionally, a multi‐objective loss function is developed to enhance the prediction results. A normalized Mahalanobis distance‐based metric is then employed to compare residual signals during bearing operation with those under normal conditions. The case study evaluates the PED observer's proficiency in accurately predicting vibration signals and assessing the performance of health indicator curves, demonstrating the proposed PED observer's superiority over conventional networks.
Metabolomics profiling for diagnosis of acute renal failure after cardiopulmonary bypass
Authors: Erdoğan Kablan Sevilay , Yılmaz Abdulkadir , Syed Hamzah , Kocabeyoğlu Sinan Sabit , Kervan Ümit , Özaltın Nuran , Nemutlu Emirhan 
Published: March 2024

RationaleAcute renal failure (ARF) is one of the most serious complications of cardiopulmonary bypass (CPB) surgery. Serum creatinine level is a key compound examined to understand whether renal function is normal. However, its level may vary based on age, gender, race, muscle mass, nutrition, and drugs taken by an individual. In addition, it may not be detected without a 50% reduction in renal function and may lead to delays in treatment. New markers are needed for early diagnosis of ARF. They were determined for early diagnosis of ARF after CPB. Metabolic differences in plasma samples of individuals who developed and did not develop ARF after cardiopulmonary bypass were determined.MethodsThis study was the first to perform an untargeted metabolomics analysis for early diagnosis of ARF after CPB surgery. Plasma samples were taken from 105 patients (9 ARF patients) at five time points to identify the time at which a more accurate ARF diagnosis can be made. A total of 687 samples, including quality control samples, were analyzed.ResultsTwo hundred twenty‐six metabolites were identified using retention index libraries. Based on the statistical evaluations, tryptophan, threonine, and methionine were found in lower concentrations in patients with ARF compared to the control group at all time points. Whereas gluconic acid, hypoxanthine, and lactic acid showed a decreasing trend over time, longitudinal analysis showed that cysteine, hippuric acid, and uric acid levels increased over time in the ARF group.ConclusionsThese metabolites are candidate biomarkers for early diagnosis of ARF as well as biomarkers for tracking the recovery of ARF patients.
Prescribed‐time constrained tracking control of a class of 2 × 2 hyperbolic PDE systems with actuator dynamics
Authors: Xiao Yu , Xu Xiaodong , Dubljevic Stevan 
Published: March 2024

AbstractThis article studies the problem of prescribed‐time constrained tracking control for a class of hyperbolic partial differential equation (PDE) systems with actuator dynamics, which are described by a set of nonlinear ordinary differential equations (ODEs). Since the control input only appears in the ODE subsystem rather than directly on the boundary of PDE subsystem, the control task becomes quite challenging. The most important is that for the control of such ODE controlled PDE systems we mainly make the following two contributions: (1) the controlled output of the PDE system tracks the reference signal within the prescribed time; (2) the controlled output and all the actuator states are constrained. It is the first time that such a prescribed‐time constrained tracking control problem is addressed for the PDE‐ODE coupled system considered in this article. Through rigorous theoretical proof, it is demonstrated that all the system states and control signals are bounded and sufficiently continuous by configuring appropriate design parameters. Finally, the performance is investigated via numerical simulation.
Early production of switchgrass (Panicum virgatum L.) and willow (Salix spp.) indicates carbon accumulation potential in Appalachian reclaimed mine and agriculture soil
Authors: Grover Salvador , Anderson Hannah M. , Fleck Jeremy , Kelly Charlene N. , Schuler Jamie , Ruark Matthew D. , Freedman Zachary B. 
Published: March 2024

AbstractThe production of bioproduct feedstocks such as switchgrass (Panicum virgatum L.) and willow (Salix spp.) on degraded lands provides an opportunity to grow dedicated bioenergy crops with the potential to capture and store carbon in the soil while reducing competition with land for food production. However, how the production of these crops alters plant–soil–microbe interactions that govern soil C accumulation in highly degraded soil is underexplored. The objectives of this study were to examine select biological and chemical properties related to stable soil organic matter (SOM) production from the growth of switchgrass and willow on marginal soil over two growing seasons and whether biochar amendment can positively affect these parameters. To address our objectives, paired former surface mined lands and non‐mine impacted marginal agriculture sites were selected across West Virginia, USA, and biochar and unamended control treatments were imposed. Through the first two growing seasons, microbial activity and demand for carbon (C) increased and was accompanied by a shift in extracellular enzyme investment for decomposition‐associated enzymes. Mineral‐associated organic matter C increased over the two growing seasons, and this increase was greater in the mine sites compared to the agriculture sites. Compared to each site's previous land use, C losses were observed under bioproduct systems in the agriculture, but not the mine sites. Biochar amendments did not impact microbial activity but did increase the C:N of SOM. Overall, our results suggest that the early growth of switchgrass and willow can result in C accumulation in marginal and highly degraded lands.
A framework for using Theory of Constraints thinking processes and tools to complement qualitative system dynamics modelling
Authors: Mabin Victoria J. , Cavana Robert Y. 
Published: March 2024

AbstractWhile the tools currently used for qualitative system dynamics (Qual SD) modelling are very powerful in providing a holistic perspective and a framework for understanding complexity and change, they are often not explicitly designed to build and implement long‐term solutions based on that understanding. The Theory of Constraints (TOC) thinking processes and tools focus on these important aspects of the decision‐making process. We provide a six‐stage framework combining selected tools from TOC's thinking process and Qual SD's modelling process to provide a more rigorous systems thinking change process. We illustrate the methods and component tools via a case study on a complex societal issue (sale of alcohol in New Zealand supermarkets) developed for teaching purposes. We demonstrate the value of the framework, highlighting complementarities between tools, and show how specific insights emerged using each of the tools, with more insights resulting from using Qual SD and TOC collectively than separately. © 2024 The Authors. System Dynamics Review published by John Wiley & Sons Ltd on behalf of System Dynamics Society.
Regression of Metastatic Malignant Melanoma with Dupilumab: A Case Report
Authors: Marr John Herbert , Al-Shammari Abbas 
Published: March 2024

Abstract
Excoriated pruritus can be an intolerable symptom in patients with cancer where Type 2 inflammation and its associated cytokines IL-4 and IL-13 play major roles in the pruritus. Dupilumab, an antibody blocking IL-4 and IL-13, is approved for treating moderate to severe atopic dermatitis (AD) where itching is a significant symptom. We present a case report of intractable malignancy-associated AD and pruritus with eosinophilia in a patient with stage IV malignant melanoma who was treated with dupilumab. Biweekly treatment with dupilumab led to an immediate improvement in itching and resolution of the AD, which subsided after a few doses and without significant adverse effects. Routine radiologic monitoring of the malignant melanoma showed concomitant resolution of secondary nodules in the lung, liver, and pleura. It was concluded that dupilumab may be a safe and effective treatment for intractable malignancy-associated AD with pruritus and may have potential for moderating metastatic malignant melanoma.
Microfluidic Impedance Cytometry Enabled One‐Step Sample Preparation for Efficient Single‐Cell Mass Spectrometry
Authors: Zhu Junwen , Pan Siyuan , Chai Huichao , Zhao Peng , Feng Yongxiang , Cheng Zhen , Zhang Sichun , Wang Wenhui 
Published: March 2024

AbstractSingle‐cell mass spectrometry (MS) is significant in biochemical analysis and holds great potential in biomedical applications. Efficient sample preparation like sorting (i.e., separating target cells from the mixed population) and desalting (i.e., moving the cells off non‐volatile salt solution) is urgently required in single‐cell MS. However, traditional sample preparation methods suffer from complicated operation with various apparatus, or insufficient performance. Herein, a one‐step sample preparation strategy by leveraging label‐free impedance flow cytometry (IFC) based microfluidics is proposed. Specifically, the IFC framework to characterize and sort single‐cells is adopted. Simultaneously with sorting, the target cell is transferred from the local high‐salinity buffer to the MS‐compatible solution. In this way, one‐step sorting and desalting are achieved and the collected cells can be directly fed for MS analysis. A high sorting efficiency (>99%), cancer cell purity (≈87%), and desalting efficiency (>99%), and the whole workflow of impedance‐based separation and MS analysis of normal cells (MCF‐10A) and cancer cells (MDA‐MB‐468) are verified. As a standalone sample preparation module, the microfluidic chip is compatible with a variety of MS analysis methods, and envisioned to provide a new paradigm in efficient MS sample preparation, and further in multi‐modal (i.e., electrical and metabolic) characterization of single‐cells.
Hybrid Interface Chemistry Enabling Mixed Conducting via Ultrafast Microwave Polarization Toward Dendrite‐Free Zn Anodes
Authors: Chen Yakai , Cao Yiyao , Chen Ke , Rui Jiayi , Chang Jingxi , Yan Yan , Lin Huijuan , Lu Yan , Zhao Cong , Zhu Jixin , Rui Kun 
Published: March 2024

AbstractZn metal anodes in aqueous electrolytes suffer from interface issues including uncontrolled dendrite growth and undesired side reactions, resulting in their limited application in terms of short circuits and cell failure. Herein, a hybrid interface chemistry strategy is developed through ultrafast microwave polarization at the skin region of bare Zn. Owing to efficient Joule heating directed by abundant local hot spots at electron valleys, the rapid establishment of a dense interfacial layer can be realized within a minute. Stabilized Zn with suppressed side reactions or surface corrosion is therefore achieved due to the interfacial protection. Importantly, hybrid zincophilic sites involving laterally/vertically interconnected Cu–Zn intermetallic compound and Zn2+‐conductive oxide species ensure mixed charge conducting (denoted as CuHL@Zn), featuring uniformly distributed electric field and boosted Zn2+ diffusion kinetics. As a consequence, CuHL@Zn in symmetric cells affords lifespans of 2800 and 3200 h with ultra‐low polarization voltages (≈19 and 56 mV) at a plating capacity of 1.0 mAh cm−2 for 1 and 5 mA cm−2, respectively. The CuHL@Zn||MnO2 full cell further exhibits cycling stability with a capacity retention of over 80% for 500 cycles at 2 A g−1.
Richen: Automated enrichment of Git documentation with usage examples and scenarios
Authors: Shen Chaochao , Yang Wenhua , Jia Haitao , Pan Minxue , Zhou Yu 
Published: March 2024

AbstractAs the predominant modern version control system, Git has become an indispensable tool for both commercial and open‐source software projects. It substantially improves software development effectiveness and efficiency through its distributed version control system, fostering seamless collaboration among teams and across locations. However, research has found that many developers have doubts about using Git commands, while the official Git documentation is rather scanty, that is, lacking sufficient explanations and examples. To help developers learn and use Git commands, we propose the first approach (Richen) for enriching Git documentation with usage examples and scenarios by leveraging crowd knowledge from Stack Overflow. Richen retrieves Git‐related posts from Stack Overflow, extracts relevant Q&A pairs, and selects representative command usages, including usage examples and scenarios, for different Git commands. Experimental results have shown that Richen can extract informative and concise command usages for Git commands. Compared with alternative methods adapted from API usage mining, the command usages obtained by Richen have significant advantages in terms of relevance, readability, and usability. Furthermore, we have shown through an empirical study that the command usages extracted by Richen can better help developers complete Git command‐related tasks.
Nanozymes‐Mediated Cascade Reaction System for Tumor‐Specific Diagnosis and Targeted Therapy
Authors: Xiong Ruru , Zhu Xiaoguang , Zhao Jiuhong , Ling Guixia , Zhang Peng 
Published: March 2024

AbstractCascade reactions are described as efficient and versatile tools, and organized catalytic cascades can significantly improve the efficiency of chemical interworking between nanozymes. They have attracted great interest in many fields such as chromogenic detection, biosensing, tumor diagnosis, and therapy. However, how to selectively kill tumor cells by enzymatic reactions without harming normal cells, as well as exploring two or more enzyme‐engineered nanoreactors for cascading catalytic reactions, remain great challenges in the field of targeted and specific cancer diagnostics and therapy. The latest research advances in nanozyme‐catalyzed cascade processes for cancer diagnosis and therapy are described in this article. Here, various sensing strategies are summarized, for tumor‐specific diagnostics. Targeting mechanisms for tumor treatment using cascade nanozymes are classified and analyzed, “elements” and “dimensions” of cascade nanozymes, types, designs of structure, and assembly modes of highly active and specific cascade nanozymes, as well as a variety of new strategies of tumor targeting based on the cascade reaction of nanozymes. Finally, the integrated application of the cascade nanozymes systems in tumor‐targeted and specific diagnostic therapy is summarized, which will lay the foundation for the design of more rational, efficient, and specific tumor diagnostic and therapeutic modalities in the future.
Organizations' readiness for insider attacks: A process‐oriented approach
Authors: AlGhamdi Azzah A. , Niazi Mahmood , Alshayeb Mohammad , Mahmood Sajjad 
Published: March 2024

AbstractContextOrganizations constantly strive to protect their assets from outsider attacks by implementing various security controls, such as data encryption algorithms, intrusion detection software, firewalls, and antivirus programs. Unfortunately, attackers strike not only from outside the organization but also from within. Such internal attacks are called insider attacks or threats, and the people responsible for them are insider attackers or insider threat agents. Insider attacks pose more significant risks and can result in greater organizational losses than outsider attacks. Thus, every organization should be vigilant regarding such attackers to protect its valuable resources from harm. Finding solutions to protect organizations from such attacks is critical. Despite the importance of this topic, little research has been conducted on providing solutions to mitigate insider attacks.ObjectiveThis study aims to develop an organizational readiness model to assess an organization's readiness for insider attacks.MethodWe conducted a multivocal literature review to identify practices that can be used to assess organizations' readiness against insider attacks. These practices were grouped into different knowledge areas of insider attacks for organizations. The insider attack readiness model was developed using identified best practices and knowledge areas: compliance, top management, human resources, and technical.ResultsThis model was evaluated at two levels—academic and real‐world environments. The evaluation results show that the proposed model can identify organizations' readiness against insider attacks.ConclusionThe proposed model can guide organizations through a secure environment against insider attacks.
The challenges of supply side obsolescence: Obsolescence procurement's past, present, and future
Authors: Schumm Joshua R. , Ralston Peter M. , Schwieterman Matthew A. 
Published: March 2024

AbstractObsolescence of critical manufacturing inputs is a major supply chain risk and represents a growing problem for procurement professionals that must be handled appropriately to profitably meet customers' needs. Supply side obsolescence occurs when suppliers end production of components and has been defined as “the loss or impending loss of original manufacturers of items or suppliers of items or raw materials.” Supply side obsolescence may radically increase costs to an organization, including high inventory holding costs, paying high prices for components on the gray market, and lost sales or lost market share due to an inability to complete products. This research utilized a grounded theory approach and discovered: (1) the risks of supply side obsolescence, (2) the impacts of supply side obsolescence on focal firms, and (3) how leading firms utilize obsolescence procurement teams to combat this potentially disastrous problem. Of specific interest to managers, obsolescence procurement teams are identified as formal teams that focus on dealing with obsolescence proactively and work to prevent the negative effects of supply side obsolescence. Finally, the study provides propositions to guide future research and concludes with suggestions for managers regarding mitigating supply side obsolescence, which will only become more urgent as the rate of technological change continues to increase.
The ancestral karyotype of the Heliantheae Alliance, herbicide resistance, and human allergens: Insights from the genomes of common and giant ragweed
Authors: Laforest Martin , Martin Sara L. , Bisaillon Katherine , Soufiane Brahim , Meloche Sydney , Tardif François J. , Page Eric 
Published: March 2024

AbstractAmbrosia artemisiifolia and Ambrosia trifida (Asteraceae) are important pest species and the two greatest sources of aeroallergens globally. Here, we took advantage of a hybrid to simplify genome assembly and present chromosome‐level assemblies for both species. These assemblies show high levels of completeness with Benchmarking Universal Single‐Copy Ortholog (BUSCO) scores of 94.5% for A. artemisiifolia and 96.1% for A. trifida and long terminal repeat (LTR) Assembly Index values of 26.6 and 23.6, respectively. The genomes were annotated using RNA data identifying 41,642 genes in A. artemisiifolia and 50,203 in A. trifida. More than half of the genome is composed of repetitive elements, with 62% in A. artemisiifolia and 69% in A. trifida. Single copies of herbicide resistance‐associated genes PPX2L, HPPD, and ALS were found, while two copies of the EPSPS gene were identified; this latter observation may reveal a possible mechanism of resistance to the herbicide glyphosate. Ten of the 12 main allergenicity genes were also localized, some forming clusters with several copies, especially in A. artemisiifolia. The evolution of genome structure has differed among these two species. The genome of A. trifida has undergone greater rearrangement, possibly the result of chromoplexy. In contrast, the genome of A. artemisiifolia retains a structure that makes the allotetraploidization of the most recent common ancestor of the Heliantheae Alliance the clearest feature of its genome. When compared to other Heliantheae Alliance species, this allowed us to reconstruct the common ancestor's karyotype—a key step for furthering of our understanding of the evolution and diversification of this economically and allergenically important group.
Individuelle und plurale epistemische Autoritäten
Authors: Hauswald Rico 
Published: March 2024

ZusammenfassungFür Millionen junger Eltern stellt sich jedes Jahr die Frage, ob und wenn ja in welcher Form sie ihre Kinder gegen die klassischen Kinderkrankheiten impfen lassen sollten. Sofern sie nicht selbst über entsprechende medizinische Kenntnisse verfügen sollten, ist es in dieser Situation – wie in vielen anderen – sicher vernünftig, eine geeignete epistemische Autorität zu konsultieren, also jemanden, der sich im Hinblick auf einen bestimmten thematischen Bereich sehr viel besser auskennt als man selbst. In diesem Fall dürfte es für die Eltern naheliegend erscheinen, zunächst den Rat ihres Kinderarztes einzuholen.
Was sind soziale Pluralitäten und was plurale epistemische Autoritäten?
Authors: Hauswald Rico 
Published: March 2024

ZusammenfassungIm dritten Teil der Untersuchung wende ich mich nun pluralen epistemischen Autoritäten zu. Damit sind soziale Pluralitäten gemeint, die in unserer epistemischen Praxis ähnliche Rollen einnehmen können wie individuelle epistemische Autoritäten. Ein wesentliches Ziel meiner Überlegungen wird im Folgenden in der Untersuchung bestehen, worin epistemische Deferenz gegenüber pluralen epistemischen Autoritäten eigentlich besteht und wie Subjekte sich gegenüber diesen rationalerweise verhalten sollten. Ich möchte demonstrieren, dass sie dabei ähnliche Herausforderungen zu bewältigen haben wie bei individuellen Autoritäten: Sie müssen Identifikationsprobleme lösen, sind unter Umständen mit Situationen konfrontiert, die Ähnlichkeiten mit Goldmans „novice/2-expert“-Problem besitzen, und stehen wiederum einem Deferenzproblem gegenüber.
Die Wahl geeigneter wahrheitsindikativer Tatsachen und die Methoden zur Feststellung ihres Bestehens
Authors: Hauswald Rico 
Published: March 2024

ZusammenfassungMit der Identifikation einer geeigneten pluralen epistemischen Autorität sind für das Subjekt noch nicht alle Herausforderungen bewältigt. Der zweite Teil des Identifikationsproblems besteht darin, das Bestehen geeigneter wahrheitsindikativer Tatsachen über die Autorität festzustellen (analog zur Feststellung, ob eine individuelle epistemische Autorität eine bestimmte Überzeugung hat). Bereits die Auswahl des geeigneten Wahrheitsindikators kann allerdings entscheidend sein.