bluuebunny/crossref_metadata_2025_split huggingface dataset:
Development and validation of a German version of the joint protection behavior assessment in patients with rheumatoid arthritis
Authors: Niedermann K. , Forster A. , Hammond A. , Uebelhart D. , de Bie R. 
Published: March 2007

AbstractObjectiveJoint protection (JP) is an important part of the treatment concept for patients with rheumatoid arthritis (RA). The Joint Protection Behavior Assessment short form (JPBA‐S) assesses the use of hand JP methods by patients with RA while preparing a hot drink. The purpose of this study was to develop a German version of the JPBA‐S (D‐JPBA‐S) and to test its validity and reliability.MethodsA manual was developed through consensus with 8 occupational therapist (OT) experts as the reference for assessing patients' JP behavior. Twenty‐four patients with RA and 10 healthy individuals were videotaped while performing 10 tasks reflecting the activity of preparing instant coffee. Recordings were repeated after 3 months for test–retest analysis. One rater assessed all available patient recordings (n = 23, recorded twice) for test–retest reliability. The video recordings of 10 randomly selected patients and all healthy individuals were independently assessed for interrater reliability by 6 OTs who were explicitly asked to follow the manual. Rasch analysis was performed to test construct validity and transform ordinal raw data into interval data for reliability calculations.ResultsNine of the 10 tasks fit the Rasch model. The D‐JPBA‐S, consisting of 9 valid tasks, had an intraclass correlation coefficient of 0.77 for interrater reliability and 0.71 for test–retest reliability.ConclusionThe D‐JPBA‐S provides a valid and reliable instrument for assessing JP behavior of patients with RA and can be used in German‐speaking countries.
Agreement between patient report and medical record review for medications used for rheumatoid arthritis: The accuracy of self‐reported medication information in patient registries
Authors: Solomon Daniel H. , Stedman Margaret , Licari Andrea , Weinblatt Michael E. , Maher Nancy , shadick Nancy 
Published: March 2007

AbstractObjectiveWith the growth in patient registries in rheumatic disease research, it is important to validate the collected information. We examined the convergent validity of self‐reported medication use for rheumatoid arthritis (RA).MethodsIn the setting of the Brigham Rheumatoid Arthritis Sequential Study (BRASS), a large registry of patients with RA, we examined the agreement between patients' self‐report of current and past RA medication use and information from medical records. For a sample of patients in BRASS, these 2 sources of information were compared using the kappa statistic as well as the percent agreement.ResultsThe 91 patients selected for assessment were typical of a prevalent RA cohort: >80% were women and the mean disease duration was 16 years. The agreement for current medication use was excellent, ranging from 0.71 for sulfasalazine to 0.96 for methotrexate. However, for past medication use agreement was lower, ranging from 0.13 for methotrexate to 0.74 for aurothioglucose. The weighted kappa for cumulative oral glucocorticoid dose was 0.67.ConclusionSelf‐report of current medication use and cumulative oral glucocorticoid dose appears to have moderate to excellent validity. However, self‐report of past medication use may not be valid.
The Pediatric Rheumatology European Society/American College of Rheumatology/European League against Rheumatism provisional classification criteria for juvenile systemic sclerosis
Authors: Zulian Francesco , Woo Patricia , Athreya Balu H. , Laxer Ronald M. , Medsger Thomas A. , Lehman Thomas J. A. , Cerinic Marco Matucci , Martini Giorgia , Ravelli Angelo , Russo Ricardo , Cuttica Ruben , de Oliveira Sheila Knupp Feitosa , Denton Christopher P. , Cozzi Franco , Foeldvari Ivan , Ruperto Nicolino ,   Pediatric Rheumatology European Society/American College of Rheumatology/European League Against Rheumatism Ad Hoc Committee on classification criteria for juvenile systemic sclerosis
Published: March 2007

AbstractObjectiveTo develop criteria for the classification of systemic sclerosis (SSc) in children (juvenile SSc).MethodsThe study consisted of 3 phases: 1) collection of data on the signs and symptoms of actual patients with juvenile SSc that are useful for defining involvement of a particular organ; 2) selection of the parameters essential for the classification of juvenile SSc and preparation of a set of provisional classification criteria (PCC) using 2 Delphi surveys; 3) consensus conference consisting of 2 steps: discussion and rating of clinical profiles of 160 patients with definite juvenile SSc, possible juvenile SSc, or other fibrosing diseases as “having or not having juvenile SSc,” using nominal group technique, and defining those PCC with the best statistical performance and highest face validity by using the clinical profiles of patients with definite juvenile SSc as the gold standard.ResultsIn phase 1, 55 centers submitted clinical data on 153 patients with juvenile SSc. A total of 48 signs and symptoms were derived from these patient data and were used to define 9 organ system categories (cutaneous, vascular, gastrointestinal, respiratory, renal, cardiac, neurologic, musculoskeletal, and serologic). During phase 2, these were reduced to 21 criteria (3 major criteria [Raynaud's phenomenon, proximal skin sclerosis/induration of the skin, and sclerodactyly] and 18 minor criteria) and combined to generate 86 different PCC. At the consensus conference, these 86 definitions were tested on the case profiles of 127 patients with juvenile SSc. The PCC with the highest ranking were proximal sclerosis/induration and at least 2 minor criteria.ConclusionThese provisional classification criteria for juvenile SSc will help standardize the conduct of clinical research, epidemiologic and outcome studies, and therapeutic trials.
Effects of 12 mT static magnetic field on sympathetic agonist‐induced hypertension in wistar rats
Authors: Okano Hideyuki , Ohkubo Chiyoji 
Published: March 2007

AbstractWe investigated the combined effects of a moderate‐intensity static magnetic field (SMF) and two different sympathetic agonists, an α1‐adrenoceptor agonist, phenylephrine and a β1‐adrenoceptor agonist, dobutamine, which induced hypertension and different hemodynamics in Wistar rats. Five‐week‐old male rats were continuously exposed to the SMF intensity of 12 mT (Bmax) with the peak spatial gradient of 3 mT/mm for 10 weeks. A loop‐shaped flexible rubber magnet was adjusted to fit snugly around the neck region of a rat (diameter‐adjustable to an animal size). Sham exposure was performed using a dummy magnet. Six experimental groups of six animals each were examined: (1) sham exposure with intraperitoneal (ip) saline injection (control); (2) SMF exposure with ip saline injection (SMF); (3) sham exposure with ip phenylephrine (1.0 µg/g) injection (PE); (4) SMF exposure with ip phenylephrine injection (SMF + PE); (5) sham exposure with ip dobutamine (4.0 µg/g) injection (DOB); (6) SMF exposure with ip dobutamine injection (SMF + DOB). Fifteen minutes after the injection of each agent, the first set of parameters, arterial blood pressure (BP) and heart rate (HR), the second set of parameters, skin blood flow (SBF) and skin blood velocity (SBV), or the third set of parameters, the number of rearing (exploratory behavior) responses and body weight was monitored. Each agent was administered three times a week for 10 weeks, and each set of parameters was monitored on different days, once a week. The dose of phenylephrine significantly increased BP and decreased HR, SBF, SBV, and the number of rearing responses in the PE group compared with those in the respective age‐matched control group. The dose of dobutamine significantly increased BP and HR, increased SBF, SBV, and the number of rearing responses in the DOB group compared with those in the control group. Continuous neck exposure to the SMF alone for up to 10 weeks induced no significant changes in any of the measured cardiovascular and behavioral parameters. The SMF exposure for at least 2 weeks (1) significantly depressed phenylephrine effects on BP, SBF, SBV, and rearing activity (SMF + PE group vs. PE group); (2) significantly depressed dobutamine effects on BP, SBF, and SBV, and suppressed dobutamine‐induced increase in the rearing activity (SMF + DOB group vs. DOB group). These results suggest that continuous neck exposure to 12 mT SMF for at least 2 weeks may depress or suppress sympathetic agonists‐induced hypertension, hemodynamics, and behavioral changes by modulating sympathetic nerve activity. Bioelectromagnetics 28:369–378, 2007. © 2007 Wiley‐Liss, Inc.
Tragverhalten von dünnen Bauteilen aus ultrahochfestem Faserfeinkornbeton
Authors: Greiner Stefan 
Published: March 2007

AbstractUltrahochfester Faserfeinkornbeton (UHFFB) eignet sich aufgrund der feinkörnigen Zuschläge und hohen Festigkeiten besonders zur Herstellung dünner Bauteile wie z. B. Schalen. Aufbauend auf eigenen Versuchsergebnissen und theoretischen Ansätzen wird das Tragverhalten von UHFFB unter Zug, Druck und Biegung untersucht. Die Gültigkeit der verwendeten Materialgesetze wird mittels Nachrechnung von Versuchen überprüft, wobei insbesondere der Einfluss der Faserorientierung berücksichtigt wird. Es wird ein Momenten‐Normalkraft‐Interaktions‐Diagramm für UHFFB erstellt. Dann werden Flächentragwerke unter kombinierter Momenten‐ und Normalkraftbeanspruchung mittels der Methode der Finiten Elemente untersucht. Die ermittelten Rissbilder und Traglasten werden mit Ergebnissen nach der Fließlinientheorie verglichen, und es werden die möglichen Lastumlagerungen diskutiert. Zur Veranschaulichung der gewonnenen Erkenntnisse wird ein Langzeitwärmespeicher berechnet und bemessen. Dazu wird das nichtlineare Bemessungsverfahren nach DIN 1045‐1 für Traglastuntersuchungen von Stahlbeton auf UHFFB übertragen.
Osteomyelitis as a complication in urology with special reference to the paravertebral venous plexus
Authors: Henriques C Q 
Published: March 2007

Abstract
“Metastatic abscesses and metastatic tumours can appear in locations that do not seem to be in line of direct spread from their primary focus. There is even a regularity of distribution of these paradoxic metastases.”—BATSON (1940).
Circulations of the cerebral hemispheres
Authors: Rowbotham G F , Little Elsa 
Published: March 2007

Abstract
On two previous occasions an account has been given of the surface arteries of the brain and of the circulation of the cerebral cortex.
In this communication it is our intention to describe the internal circulation of the cerebral hemispheres and the anatomy of the surface veins and venous sinuses. Also, we hope to link up our previous papers with this one and to discuss and illustrate the phenomena that we believe are of special surgical importance and particularly those that influence surgical techniques.
New concepts on the aetiology and vascularization of meningiomata; the mechanisms of migraine; the chemical processes of the cerebrospinal fluid; and the formation of collections of blood or fluid in the subdural space
Authors: Rowbotham G F , Little Elsa 
Published: March 2007

Abstract
In this communication it is our intention to describe in detail the vascular anatomy of the dura mater, and particularly as its peculiarities throw light on the actiology and vascularization of the meningiomata, a class of tumours that has played a large part in the moulding of the techniques of neurosurgery. We believe that our work also helps in the elucidation of the puzzling phenomena of the circulation and chemistry of the cerebrospinal fluid. The relevant pathological activities of the subdural space and the mechanisms of migraine will also be discussed.
Liver fluke in the common bile-duct
Authors: Munro A I 
Published: March 2007

Abstract
In Great Britain the liver fluke, Fasciola hepatica, has been surgically removed from the common bile- duct on seven occasions: all the patients have been women, and 2 came from the Bath clinical area (Murphy and Pascall, 1950). A further case, this time a man, also from the Bath clinical area, is presented (Table 1).
Malignant ascites
Authors: Parsons S L , Watson S A , Steele R J C 
Published: March 2007

Abstract
Investigation and treatment of malignant ascites are often in the hands of the general surgeon and can be difficult. This article considers the aetiology and pathophysiology of malignant ascites and explores the best form of management. Established treatment modalities and new therapeutic options are reviewed and a new management regimen based on a knowledge of the tumour of origin is proposed, which aims to balance potential benefit against morbidity.
Treatment of non-disseminated cancer of the lower rectum
Authors: Nicholls R J , Hall C 
Published: March 2007

AbstractApart from the occasional tumour which is suitable for local excision, most low rectal cancers are best treated by anterior resection with complete removal of the rectum; the construction of a coloanal reservoir should allow routine sphincter saving. This surgery may be carried out independently of adjuvant radiotherapy which, if given, should be administered before operation.
Cell proliferation kinetics are abnormal in transitional mucosa adjacent to colorectal carcinoma
Authors: Yoshikawa R , Utsunomiya J 
Published: March 2007

Abstract
The transitional mucosa adjacent to colorectal carcinoma shows characteristic morphological and histochemical abnormalities that may be indicative of premalignant changes. Sixteen colorectal carcinomas were studied to analyse the proliferative activity and its distribution pattern in tissue samples from transitional mucosa located within 2 cm of the cancer and from uninvolved mucosa 10 cm from the cancer. Proliferative activity was assessed using a monoclonal antibody to proliferating cell nuclear antigen (PCNA). The total labelling index (percentage of labelled cells in a column) of transitional mucosa was not significantly different from that of uninvolved mucosa and normal control mucosa but it was significantly higher in cancer tissue (P&lt;0.001). An upward shift of the compartment of proliferating epithelial cells towards the bowel lumen was seen in transitional mucosa. The labelling index of the middle compartment (compartment 3) of the crypt in transitional mucosa was significantly higher than that in uninvolved mucosa and control mucosa (P&lt;0.001). Unstable cytokinetic change may already have started in apparently normal transitional mucosa. Assessment of cell proliferation kinetics by PCNA immunostaining may be useful in screening for heightened risk of the development of colorectal cancer.
Long-term outcome following curative surgery for malignant large bowel obstruction
Authors: Mulcahy H E , Skelly M M , Husain A , O'Donoghue D P 
Published: March 2007

Abstract
This study determined whether the long-term outcome of patients with obstructing colorectal cancer could be related to conventional pathological prognostic variables or to other clinical, operative or histological features. Ninety-eight patients with bowel obstruction who had undergone potentially curative surgery and survived the postoperative period were studied. Features related to poor long-term outcome after a median follow-nup of 5 years included bowel perforation at initial operation (P = 0.007), advanced tumour stage (P&lt; 0.001), poor tumour differentiation (P = 0.02), mucin production by tumour (P = 0.004) and the presence of vascular (P = 0.08) and neural (P = 0.004) invasion. Outcome was not significantly related to the seniority of the operating surgeon (P = 0.52), even when this was adjusted for potentially confounding variables (adjusted hazard rate ratio for trainee surgeons 1.4 (95 per cent confidence interval 0.9–2.4), P = 0.16). Conventional prognostic features may help to identify the majority of patients with obstructed colorectal cancer at high risk of tumour recurrence and death.
Wandering spleen: A rare emergency condition
Authors: Papakyriacou K , Nicolaou N , Symeonides P 
Published: March 2007

Abstract
Wandering spleen is a rare emergency condition1,2 in which the spleen is characterized by a long vascular pedicle, displacement from its normal position and quite often devoid of its peritoneal ligaments. It is usually asymptomatic or may present with a shifting mass in the abdomen with abdominal heaviness, vague gastrointestinal disturbance and sometimes with hypersplenism or as an emergency condition due to torsion3.
Total anorectal reconstruction results in complete anorectal sensory loss
Authors: Abercrombie J F , Rogers J , Williams N S 
Published: March 2007

Abstract
Six patients underwent objective measurement of anorectal sensory function following abdominoperineal excision of the rectum and total anorectal reconstruction. No patient perceived neorectal distension as a desire to defaecate or as a feeling of flatus. Anal mucosal sensation was preserved in two patients in whom some anal mucosa was retained. These sensory deficiencies may result in faecal retention and incontinence in patients undergoing reconstructive surgery. The loss of rectal sensation suggests that the prime sensors of rectal filling may lie within the rectum itself.
Ischaemic nature of anal fissure
Authors: Schouten W R , Briel J W , Auwerda J J A , de Graaf E J R 
Published: March 2007

Abstract
Microvascular perfusion of the anoderm was assessed by laser Doppler flowmetry in 27 patients with anal fissure. Anal pressure was recorded simultaneously. Both measurements were repeated 6 weeks after lateral internal sphincterotomy and compared with those obtained from 27 controls. Mean(s.d.) maximum anal resting pressure was significantly higher in those with a fissure than in controls (121.07(24.48) versus 68.78(16.97) mmHg, P&lt; 0.001). Anodermal blood flow at the fissure site was significantly lower than at the posterior commissure of the controls (0.46(0.20) versus 0.76(0.28) V, P&lt;0.001). The fissure healed in 24 patients within 6 weeks of sphincterotomy. In these patients a significant pressure decrease was noted (35 per cent) which was accompanied by a consistent rise in blood flow (65 per cent) at the original fissure site. The increased internal sphincter tone in patients with a fissure reduces anodermal blood flow at the posterior midline. Reduction of anal pressure by sphincterotomy improves anodermal blood flow at the posterior midline, resulting in fissure healing. These findings provide evidence for the ischaemic nature of anal fissure.
Diaphragmatic herniation after penetrating trauma
Authors: Degiannis E , Levy R D , Sofianos C , Potokar T , Florizoone M G C , Saadia R 
Published: March 2007

Abstract
A study was made of 45 patients with diaphragmatic herniation after penetrating trauma. In 29 the diagnosis was established during the first admission (early presentation) and in 16 during a subsequent admission (delayed presentation). The mortality rate in the early presentation group was 3 per cent compared with 25 per cent in the delayed presentation group. The presence of gangrenous or perforated abdominal viscus in the chest cavity was the single most common and severe aggravating factor. The need for diagnosis of diaphragmatic herniation during the initial admission is emphasized. As isolated diaphragmatic injuries provide few helpful clinical features to aid diagnosis, appropriate investigations and good follow-up are of paramount importance in preventing late herniation of intra-abdominal viscera through a penetrating diaphragmatic injury.
‘Soup ladle’ autotransfusion
Authors: Ansaloni L , Gaines C , Tocalli E 
Published: March 2007

Abstract
Autotransfusion is the collection and reinfusion of the patient's own blood. This technique can help in response to the increasing demand for blood and the heightening awareness of transfusion morbidity1. A simple, low cost, perioperative autotransfusion technique that can be easily practised by all surgeons is described.
Midgut volvulus in children
Authors: Kealey W D C , McCallion W A , Brown S , Potts S R , Boston V E 
Published: March 2007

Abstract
Midgut volvulus secondary to intestinal malrotation usually presents within the first month of life, typically with persistent bilious vomiting1. Diagnostic delay may result in midgut infarction and death. Malrotation may, however, remain quiescent during early childhood and present later in life. Over a 15-year interval, seven patients presented with midgut volvulus well beyond infancy. These cases illustrate important features in presentation which may not be familiar to general surgeons in district general hospitals who may have to deal with this problem.
Repeat hepatectomy for recurrent hepatocellular carcinoma
Authors: Nagasue N , Kohno H , Hayashi T , Uchida M , Ono T , Yukaya H , Yamanoi A 
Published: March 2007

Abstract
This study evaluated the results of repeat hepatectomy for recurrent hepatocellular carcinoma (HCC) and delineated the limitations of such a treatment strategy. Of 290 patients who had radical hepatic resection, 167 had intrahepatic tumour recurrence. Fifty patients underwent a second hepatectomy. Third and fourth hepatectomies were carried out on six and two patients respectively. There were 36 men and 14 women. Age ranged from 32 to 77 years (mean 59.1 years). Liver cirrhosis was present in 38 and chronic hepatitis in 12 patients. Operative death occurred in four patients (8 per cent) after a second and in one of six after a third hepatectomy, compared with 4.5 per cent after first hepatectomy. The five postoperative deaths were attributed to either Child grade B or C liver disease, or severe intraoperative bleeding. The 5-year survival rate was better in these 50 patients (41 per cent) than in 117 patients who were treated otherwise (7 per cent). The present study indicates that repeat hepatectomy may be useful for recurrent HCC. It is indicated principally for patients with a solitary tumour and Child grade A liver disease.
Sisters with familial adenomatous polyposis affected with thyroid carcinoma, desmoid tumour and duodenal polyposis
Authors: Kashiwagi H , Konishi F , Kanazawa K , Miyaki M 
Published: March 2007

Abstract
After prophylactic surgery for colonic polyposis, upper gastrointestinal cancer and desmoid tumour are the main causes of death in patients with familial adenomatous polyposis (FAP). Two sisters with FAP who developed multicentric carcinoma of the thyroid, desmoid tumour and duodenal polyposis are presented.
Day-case laparoscopic hernia repair
Authors: Evans D S , Ghaneh P , Khan I M 
Published: March 2007

Abstract
Some 114 patients (median age 52 years) underwent laparoscopic hernia repair as a day-case procedure. Twenty-one patients had bilateral and 11 recurrent hernias. Some 113 patients underwent transabdominal preperitoneal mesh repair but one required conversion to open operation. Mean operating time was 24 min for unilateral and 38 min for bilateral repair. In an operating session of 3·5 h, up to five patients (mean 4·4) underwent surgery and as many as seven hernias were repaired. More than 10 per cent of patients were found to have a previously undiagnosed hernia on the opposite side. A total of 111 patients were discharged home on the day of surgery. Major complications included one omental bleed and one small bowel obstruction. Seroma was the commonest minor complication and occurred in 7 per cent of patients. More than 35 per cent of patients needed no postoperative analgesia. To date there has been one recurrence (follow-up range 2–18 months).