bluuebunny/crossref_metadata_2025_split huggingface dataset:
Agenten: Technologie für den Mainstream? (Agents: Technology for the Mainstream?)
Authors: Pokahr Alexander , Braubach Lars , Lamersdorf Winfried 
Published: October 2005

Zusammenfassung
Agententechnologie wird als ein vielversprechender Ansatz gesehen, die Probleme der Konstruktion komplexer Software-Systeme wie heterogene Systemumgebungen und dezentrale Strukturen besser beherrschbar zu machen. Dieser Beitrag wirft einen kritischen Blick auf den erreichten Stand der softwaretechnischen Unterstützung, den die Agententechnologie bei der Systementwicklung bietet. Da die Agententechnologie ein stark diversifiziertes Feld ist, wird versucht die unterschiedlichen Einflussfaktoren und ihre Wechselwirkungen aufzuzeigen. Zudem wird durch Beispiele aus der Praxis belegt, für welche Anwendungsfelder die vorgestellten Technologien besonders gut geeignet sind.
Bildbasierte vektorielle Geschwindigkeitsmessung texturierter Oberflächen (Image-based Vectorial Velocity Measurement of Textured Surfaces)
Authors: Horn Jan 
Published: October 2005

Abstract
In der Fahrzeugtechnik ist die Information von Betrag und Richtung der Fahrzeuggeschwindigkeit von äußerster Wichtigkeit. Zur Realisierung eines berührungslosen optischen Messverfahrens eignen sich dabei insbesondere CMOS-Kameras. Diese erlauben Hochgeschwindigkeitsaufnahmen schnell bewegter Objekte bei sehr kurzen Belichtungszeiten. Durch Analyse einer Bildsequenz der bewegten Straßenoberfläche mit Methoden der Bildverarbeitung kann die Relativbewegung zwischen Kamera und Oberfläche und somit die Bewegung des Fahrzeugs gemessen werden. In diesem Beitrag wird beschrieben, wie durch Beobachtung der Fahrbahn mit einer CMOS-Kamera die Kenngrößen der Fahrzeugbewegung – Geschwindigkeitsvektor und Drehrate – gemessen werden können. Anhand von korrespondierenden Punkten in aufeinander folgenden Bildern werden Transformationsparameter geschätzt. Geschwindigkeitsvektor und Drehrate können direkt aus diesen Parametern berechnet werden.
Koeffizienten und Ausgleichsrechnung: Die Messunsicherheit nach GUM. Teil 1: Ausgleichsgeraden (Coefficients and Adjustment Calculations: Measurement Uncertainty under GUM. Part 1: Best Fit Straight Lines)
Authors: Matus Michael 
Published: October 2005

Abstract
Die Bestimmung des linearen thermischen Ausdehnungskoeffizienten eines Prüflings ist ein typisches Beispiel, wie die eigentliche Messgröße durch eine Ausgleichsrechnung aus einer veränderlichen Anzahl von Messdaten gewonnen wird. Die notwendige Angabe der Messunsicherheit (nach GUM) solcher Größen bereitet den Anwendern erfahrungsgemäß große Schwierigkeiten. In dieser Arbeit werden für Praktiker GUM-konsistente Formeln für die Messunsicherheit der Koeffizienten von Ausgleichsgeraden abgeleitet.
Use of GIS-Derived Landscape-Scale Habitat Features to Explain Spatial Patterns of Fish Density in Michigan Rivers
Authors: Creque Sara M. , Rutherford Edward S. , Zorn Troy G. 
Published: October 2005

Abstract
Both site- and landscape-scale processes play important roles in the biological communities of rivers. Understanding the influences of these processes on fish abundance can help direct management and research efforts toward appropriate habitat variables and scales. We used multiple linear regression analysis of a regional fish and habitat database to determine the feasibility of using geographical information systems (GIS)–derived landscape-scale habitat variables to explain the spatial variation in the density of five sport fish species (Chinook salmon Oncorhynchus tshawytscha, steelhead O. mykiss, brown trout Salmo trutta, brook trout Salvelinus fontinalis, and white sucker Catostomus commersonii) in the rivers of Michigan's Lower Peninsula. We compared these models with those developed using site-scale variables traditionally measured in the field. Landscape-scale riverine habitat variables obtained through GIS analysis and modeling of catchment characteristics accounted for 18–69% of the variation in fish density. Landscape estimates of mean July water temperature were negatively correlated with the density of brook trout, brown trout, and Chinook salmon. Drainage area was negatively correlated with the density of steelhead and white suckers, and 90% exceedence flow yield (a measure of flow stability) was positively correlated with the density of Chinook salmon and steelhead. Site-scale habitat variables explained less (12–57%) of the variation in fish density than landscape-scale variables. In the site-scale models, depth was negatively related to all species' densities, and the percentage of soft substrates was positively correlated only with white suckers. Although there was still much unexplained variation in density, our models provide insight into key habitat variables that influence fish density patterns on a large scale.
Facile processing of clays into organically‐modified aerogels
Authors: Somlai Louis S. , Bandi Suneel A. , Schiraldi David A. , Mathias Lon J. 
Published: October 2005

AbstractA facile process for the conversion of clay powders to organically modified clay aerogels (OMCAs) is reported. The resultant clay aerogels are of potential interest for a variety of applications, by themselves, or as a component in composite materials. Freeze‐drying aqueous clay‐surfactant solutions isolates these highly organized materials. Robust OMCAs are formed from clay‐surfactant compositions that initially produce stable surfactant modified clay‐water suspensions. Characterization of the OMCA by FTIR, WAXD, and TGA confirms the retention of surfactant after freeze‐drying, while SEM and porosimetry data show a structural reorganization of clay sheet bundles. © 2005 American Institute of Chemical Engineers AIChE J, 2006
Successful umbilical cord blood transplantation for severe chronic active Epstein‐Barr virus infection after the double failure of hematopoietic stem cell transplantation
Authors: Ishimura Masataka , Ohga Shouichi , Nomura Akihiko , Toubo Taikai , Morihana Eiji , Saito Yusuke , Nishio Hisanori , Ide Makoto , Takada Hidetoshi , Hara Toshiro 
Published: October 2005

AbstractAn 11‐year‐old boy with severe chronic active Epstein‐Barr virus infection (CAEBV) underwent successful cord blood transplantation (CBT) after consecutive failure of peripheral blood and bone marrow transplantation from his HLA‐mismatched mother. CB cells from an unrelated donor were infused after conditioning with total body irradiation (12 Gy), melphalan (120 mg/m2), and etoposide (600 mg/m2). Complete remission without circulating EBV‐DNA has continued for 15 months after a delayed hematologic recovery. This is the first successful report of CBT for CAEBV. CB may therefore be an alternate source of stem cells for the curative treatment of CAEBV, despite the absence of EBV‐specific cytotoxic T lymphocytes. Am. J. Hematol. 80:207–212, 2005. © 2005 Wiley‐Liss, Inc.
Possible association between Budd‐Chiari syndrome and gemtuzumab ozogamicin treatment in a patient with refractory acute myelogenous leukemia
Authors: Kurt Mevlüt , Shorbagi Ali , Altundag Kadri , Elkiran Tamer , Güllü Ibrahim , Kansu Emin 
Published: October 2005

AbstractGemtuzumab ozogamicin (GO; CMA‐676; Mylotarg™) is a chemotherapeutic agent approved for the treatment of CD33‐positive acute myelogenous leukemia in patients of age 60 years or older after first relapse. Hepatic veno‐occlusive disease has been reported to develop as a late complication of gemtuzumab ozogamicin treatment. A patient who developed Budd‐Chiari Syndrome with hepatic vein thrombosis following treatment with GO is presented. This complication has not been previously reported, and it deserves to be considered as a possible adverse effect of gemtuzumab ozogamicin. Am. J. Hematol. 80:213–215, 2005. © 2005 Wiley‐Liss, Inc.
Minimal residual disease (MRD) monitoring using rearrangement of T‐cell receptor and immunoglobulin H gene in the treatment of adult acute lymphoblastic leukemia patients
Authors: Toubai Tomomi , Tanaka Junji , Ota Shuichi , Fukuhara Takashi , Hashino Satoshi , Kondo Takeshi , Kasai Masaharu , Kakinoki Yasutaka , Masauzi Nobuo , Morioka Masanobu , Kawamura Tsugumichi , Iwasaki Hiroshi , Asaka Masahiro , Imamura Masahiro 
Published: October 2005

AbstractWe evaluate whether molecular monitoring of minimal residual disease (MRD) using TCR δ (TCRD), TCR γ (TCRG), and immunoglobulin H (IgH) gene rearrangements in the bone marrow (BM) is correlated with clinical events in ALL patients. The 14 patients enrolled in this study included 6 males and 8 females with a median age of 53 years (range, 25–79 years), and the median duration of follow‐up was 417 days (range, 57–617 days). The median WBC count was 11.3 × 109/L at diagnosis. All patients had L2 type ALL. Eleven patients had a monoclonal pattern of IgH (7), TCRD (3) and TCRG (1), and 3 patients had two clonal patterns. Eleven of the 14 patients achieved the first complete remission (CR) after the first induction chemotherapy. We analyzed 9 of 11 CR patients who could be examined immediately after induction chemotherapy (including re‐induction therapy). Event‐free survival (EFS, 0%) and disease‐free survival (DFS, 0%) at 1 year in CR patients with MRD level ≥10−3 (n = 3) were significantly lower than those in CR patients with MRD level <10−3 (n = 6) (log‐rank test, P = 0.013, 0.013). A lower MRD in BM value after induction chemotherapy was associated significantly with longer survival in the log‐rank test. Our data provide evidence that molecular MRD status of BM is a strong predictor of outcome in adult ALL. Am. J. Hematol. 80:181–187, 2005. © 2005 Wiley‐Liss, Inc.
Prevention of hepatitis B reactivation with lamivudine in hepatitis B virus carriers with hematologic malignancies treated with chemotherapy—A prospective case series
Authors: Vassiliadis Themistoklis , Garipidou Vassilia , Tziomalos Konstantinos , Perifanis Vassilios , Giouleme Olga , Vakalopoulou Sofia 
Published: October 2005

AbstractAdministration of immunosuppressive treatment in hepatitis B virus carriers with malignancies is associated with the risk of hepatitis B reactivation. This complication is more frequent in patients with hematologic malignancies because administration of corticosteroids, the mainstay of treatment of these patients, is an independent risk factor for hepatitis B reactivation. When lamivudine is given prior to chemotherapy, it prevents the viral replication during the immunosuppression period; therefore, it might reduce the risk of hepatitis B exacerbation. We performed a prospective study to assess the efficacy of prophylactic administration of lamivudine in this setting. Ten hepatitis B virus carriers with hematologic malignancies were included in this study; seven were HBsAg positive, and three had isolated antiHBc and detectable HBV‐DNA levels. Nine patients were given corticosteroids after the administration of lamivudine. Lamivudine was given per os at a dose of 100 mg once daily. In four patients that had not been previously treated with chemotherapy, lamivudine was started 19 days (median) (range, 0–35 days) prior to the onset of chemotherapy. The administration of lamivudine has not stopped since in any of our patients. After a median follow‐up of 15 months (range 6–38 months), no hepatitis B reactivation was observed. HBV‐DNA levels were decreased in all 6 patients who had detectable HBV‐DNA at baseline. Lamivudine was well tolerated. Chemotherapy regimens were administered as planned, and their effectiveness was not compromised by lamivudine. In conclusion, prophylactic administration of lamivudine should be considered as a means of reducing the frequency of hepatitis B reactivation in hepatitis B virus carriers with hematologic malignancies who are being treated with chemotherapy. Am. J. Hematol. 80:197–203, 2005. © 2005 Wiley‐Liss, Inc.
Subgroups of Alzheimer's disease based on cerebrospinal fluid molecular markers
Authors: Iqbal Khalid , Flory Michael , Khatoon Sabiha , Soininen Hilkka , Pirttila Tuula , Lehtovirta Maarit , Alafuzoff Irina , Blennow Kaj , Andreasen Niels , Vanmechelen Eugeen , Grundke‐Iqbal Inge 
Published: October 2005

AbstractAlzheimer's disease, the most common cause of dementia, is multifactorial and heterogeneous; its diagnosis remains probable. We postulated that more than one disease mechanism yielded Alzheimer's histopathology, and that subgroups of the disease might be identified by the cerebrospinal fluid (CSF) levels of proteins associated with senile (neuritic) plaques and neurofibrillary tangles. We immunoassayed levels of tau, ubiquitin, and Aβ1‐42 in retrospectively collected CSF samples of 468 clinically diagnosed Alzheimer's disease patients (N = 353) or non‐Alzheimer's subjects (N = 115). Latent profile analysis assigned each subject to a cluster based on the levels of these molecular markers. Alzheimer's disease was subdivided into at least five subgroups based on CSF levels of Aβ1‐42, tau, and ubiquitin; each subgroup presented a different clinical profile. These subgroups, which can be identified by CSF analysis, might benefit differently from different therapeutic drugs. Ann Neurol 2005;58:748–757
Do‐it‐yourself information technology: Role hybridization and the design–use interface
Authors: Fleischmann Kenneth R. 
Published: October 2005

AbstractInformation technology designers and users are generally treated as interacting yet distinct groups. Although approaches such as participatory design attempt to bring these groups together, such efforts are viewed as temporary and restricted to a specific knowledge domain where users can share key information and insights with designers. The author explores case studies that point to a different situation, role hybridization. Role hybridization focuses on the ability of individuals to shift from one knowledge domain to another, thus allowing for simultaneous membership within two otherwise distinct social worlds. While some studies focus on the ability of designers to act as users, this study focuses on the opposite situation, users who become designers. Interview and participant observation data is used to explore hybrid user–designers in two case studies: frog dissection simulations used in K‐12 biology education and human anatomy simulations used in medical education. Hybrid users as designers are one part of a larger design–use interface, illustrating the mutually constructive relationship between the activities of information technology design and use. Users as designers also challenge the traditional power relationship between designers and users, leading to a novel and exciting form of user‐centered design.
QPO as the Rosetta Stone for understanding black hole accretion
Authors: Abramowicz M. A. 
Published: October 2005

AbstractQuasi‐periodic oscillations (QPO) seen in the X‐ray fluxes of individual neutron stars and black hole sources are one of most intriguing phenomena in today's astrophysics. The QPO nature is visibly determined by super‐strong Einstein's gravity. I argue here that it also profoundly depends on the MRI turbulence in accretion flows. Understanding the QPO physics may therefore guide accretion theory out of its present state of confusion. Readers will find here an up‐to‐date, comprehensible account of what is known, and what is not, about the QPO physics. (© 2005 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
Turbulence and its parameterization in accretion discs
Authors: Brandenburg A. 
Published: October 2005

AbstractAccretion disc turbulence is investigated in the framework of the shearing box approximation. The turbulence is either driven by the magneto‐rotational instability or, in the non‐magnetic case, by an explicit and artificial forcing term in the momentum equation. Unlike the magnetic case, where most of the dissipation occurs in the disc corona, in the forced hydrodynamic case most of the dissipation occurs near the midplane. In the hydrodynamic case evidence is presented for the stochastic excitation of epicycles. When the vertical and radial epicyclic frequencies are different (modeling the properties around rotating black holes), the beat frequency between these two frequencies appear to show up as a peak in the temporal power spectrum in some cases. Finally, the full turbulent resistivity tensor is determined and it is found that, if the turbulence is driven by a forcing term, the signs of its off‐diagonal components are such that this effect would not be capable of dynamo action by the shear–current effect. (© 2005 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
X‐ray spectral states and high‐frequency QPOs in black holebinaries
Authors: Remillard R. A. 
Published: October 2005

AbstractThe high‐frequency quasi‐periodic oscillations (HFQPOs) in the X‐ray emission of black hole binaries and candidates are briefly reviewed with respect to the question of X‐ray states. We use the prescription of McClintock & Remillard (2005), in which X‐ray spectra and power density spectra are used to differentiate three main states of active accretion: “thermal”, “hard”, and “steep power‐law”. Respectively, each state emphasizes a different physical element that may contribute radiation: the accretion disk, a jet, and a compact non‐thermal corona. We focus on the four sources that exhibit pairs of HFQPOs with frequencies that scale in a 3:2 ratio. All of these HFQPOs are associated with the steep power‐law (SPL) state. Furthermore, there is a clear trend in which the 2ν 0 oscillation is seen when the source has high X‐ray luminosity, while the 3ν 0 QPO is seen at lower luminosity. (© 2005 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
The QPO phenomenon
Authors: van der Klis M. 
Published: October 2005

AbstractAspects of QPOs in the X‐ray flux of low mass X‐ray binaries are reviewed, with particular attention to the comparison between the QPOs in black holes and those in neutron stars. (© 2005 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
Drop of coherence of the lower kilo‐Hz QPO in neutron stars: Is there a link with the innermost stable circular orbit?
Authors: Barret D. , Olive J.‐F. , Coleman Miller M. 
Published: October 2005

AbstractUsing all available archival data from the Rossi X‐ray Timing Explorer (RXTE), we follow the frequency of the kilo‐Hz QPOs in three low luminosity neutron star low mass X‐ray binaries; namely 4U 1636‐536, 4U 1608‐522, and 4U 1735‐44. Following earlier work by Barret et al. (2005a,b), we focus our analysis on the lower kilo‐Hz QPO, for which we study the dependency of its quality factor (Q = ν/ Δν , where Δν is the FWHM) and amplitude as a function of frequency over a range covering from 500 Hz to 1000 Hz. As previously found for 4U 1636‐536, we show that the quality factor of the lower kilo‐Hz increases with frequency up to a maximum frequency around 800 Hz, beyond which an abrupt drop of its coherence is observed down to a limiting frequency where the QPO disappears completely. Simultaneously the amplitude of the QPOs is almost constant below the peak frequency and starts to decrease smoothly afterwards. The peak frequency is 850 Hz, 820 Hz, 740 Hz whereas the limiting frequency is 920 Hz, 900 Hz and 830 Hz for 4U 1636‐536, 4U 1608‐522 and 4U 1735‐44 respectively. A ceiling of the lower QPO frequencies is also seen clearly in a frequency versus count rate diagram for all sources. This behavior is reproducible within an object and between objects. We suggest here that the drop of coherence of the lower QPO may be a geometry‐related effect, which could be related to the last stable circular orbit. (© 2005 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
The statistics of Sco X‐1 kHZ QPOs
Authors: Bulik T. 
Published: October 2005

AbstractRecently an additional technique was applied to investigate the properties of kHz QPOS, i.e. the analysis of the distribution of frequency ratios or frequencies themselves. I review the results of such work on the data from Sco X‐1: (Abramowicz et al. 2003), which was later criticized by Belloni, Méndez & Homan (2005). I .nd that the findings of the latter paper are consistent with results presented earlier: kHz QPOs cluster around the value corresponding to the frequency ratio of 2/3. I also discuss the random walk model of kHz QPOs and possible future observations needed to verify it. (© 2005 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
Boundary layer emission in luminous LMXBs
Authors: Gilfanov M. , Revnivtsev M. 
Published: October 2005

AbstractWe show that aperiodic and quasiperiodic variability of bright LMXBs – atoll and Z‐sources – on ∼ sec‐msec time scales is caused primarily by variations of the luminosity of the boundary layer. The emission of the accretion disk is less variable on these time scales and its power density spectrum follows P disk(f ) ∝ f –1 law, contributing to observed flux variation at low frequencies and low energies only. The kHz QPOs have the same origin as variability at lower frequencies, i.e. independent of the nature of the “clock”, the actual luminosity modulation takes place on the neutron star surface. The boundary layer spectrum remains nearly constant in the course of the luminosity variations and is represented to certain accuracy by the Fourier frequency resolved spectrum. In the investigated range of $ \dot M $ ∼ (0.1 – 1) $ \dot M $Edd it depends weakly on the global mass accretion rate and in the limit $ \dot M $ ∼ $ \dot M $Edd is close toWien spectrum with kT ∼ 2.4 keV. Its independence on the global value of $ \dot M $ lends support to the theoretical suggestion by Inogamov & Sunyaev (1999) that the boundary layer is radiation pressure supported.Based on the knowledge of the boundary layer spectrum we attempt to relate the motion along the Z‐track to changes of physically meaningful parameters. Our results suggest that the contribution of the boundary layer to the observed emission decreases along the Z‐track from conventional ∼50% on the horizontal branch to a rather small number on the normal branch. This decrease can be caused, for example, by obscuration of the boundary layer by the geometrically thickened accretion disk at $ \dot M $ ∼ $ \dot M $Edd. Alternatively, this can indicate significant change of the structure of the accretion flow at $ \dot M $ ∼ $ \dot M $Edd and disappearance of the boundary layer as a distinct region of the significant energy release associated with the neutron star surface. (© 2005 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
High frequency QPOs, nonlinear oscillations in strong gravity
Authors: Kluźniak W. 
Published: October 2005

AbstractSome of the more promising ideas about the origin of the high frequency variability (kHz QPOs) in the observed X‐ray emissions of low‐mass X‐ray binaries are contrasted with less promising ones. (© 2005 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
Direct Fmoc/tert‐Bu solid phase synthesis of octamannosyl polylysine dendrimer–peptide conjugates
Authors: Kantchev Eric Assen B. , Chang Chung‐Chieh , Chang Ding‐Kwo 
Published: October 2005

AbstractThe mannose binding proteins on the surface of the dendritic cells are responsible for capture of pathogens in the early stages of immune response. Conjugation to mannose dendrimers is a rarely explored but potentially powerful strategy for enhancing immunogenicity of synthetic peptides relying on direct delivery to dendritic cells. We describe a general protocol for preparation of pure, monodisperse third‐generation mannosylated poly‐L‐lysine dendrimer‐peptide conjugates using direct, machine‐assisted Fmoc/t‐Bu solid phase peptide synthesis. The glycodendrons were elaborated onto the N‐ or C‐terminus of sequences derived from HIV‐1 gp41, SARS‐CoV S2 protein, and Influenza Hemagglutinin (consisting of 15–44 residues). The products were obtained in a homogeneous state after cleavage from the resin, deprotection, and a single purification on semipreparative RP–HPLC. © 2005 Wiley Periodicals, Inc. Biopolymers (Pept Sci) 84: 232–240, 2006This article was originally published online as an accepted preprint. The “Published Online” date corresponds to the preprint version. You can request a copy of the preprint by emailing the Biopolymers editorial office at biopolymers@wiley.com