bluuebunny/crossref_metadata_2025_split huggingface dataset:
An Efficient and Facile Synthesis of Quinoxaline Derivatives Catalyzed by KHSO4 at Room Temperature.
Authors: Oskooie Hossein A. , Heravi Majid M. , Bakhtiari Khadijeh , Taheri Shima 
Published: November 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
TMSCl‐Promoted Isocyanide‐Based MCR of Ethylenediamines: An Efficient Assembling of 2‐Aminopyrazine Core.
Authors: Kysil Volodymyr , Tkachenko Sergey , Khvat Alexander , Williams Caroline , Tsirulnikov Sergey , Churakova Marina , Ivachtchenko Alexandre 
Published: November 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Reactivity of Cyclic Sulfamidates Towards Phosphonate‐Stabilized Enolates: Synthesis and Applications of α‐Phosphono Lactams.
Authors: Bower John F. , Williams Andrew J. , Woodward Hannah L. , Szeto Peter , Lawrence Ron M. , Gallagher Timothy 
Published: November 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Synthesis of 2‐Aryl‐5‐styrylphospholes: Promising Candidates for the Phosphole‐Based NLO Chromophores.
Authors: Matano Yoshihiro , Miyajima Tooru , Imahori Hiroshi , Kimura Yoshifumi 
Published: November 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
A Stereodivergent Route to Epimeric 2‐Piperidinylglycines: Application to the Synthesis of Carbocyclic β‐Lactam Derivatives.
Authors: Chattopadhyay Shital K. , Sarkar Kaushik , Thander Latibuddin , Roy Shankar P. 
Published: November 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Cyclonatsudamine A, a New Vasodilator Cyclic Peptide from Citrus natsudaidai.
Authors: Morita Hiroshi , Enomoto Maiko , Hirasawa Yusuke , Iizuka Toru , Ogawa Kazunori , Kawahara Nobuo , Goda Yukihiro , Matsumoto Teruki , Takeya Koichi 
Published: November 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Intramolecular 1,5‐Hydrogen Atom Transfer Reaction Promoted by Phosphoramidyl and Carbamoyl Radicals: Synthesis of 2‐Amino‐C‐glycosides.
Authors: Francisco Cosme G. , Herrera Antonio J. , Martin Angeles , Perez‐Martin Ines , Suarez Ernesto 
Published: November 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Efficient Stereoselective Synthesis of Oligosaccharides of Streptococcus pneumoniae Serotypes 6A and 6B Containing Multiple 1,2‐cis Glycosidic Linkages.
Authors: Parameswar Archana R. , Pornsuriyasak Papapida , Lubanowski Nicole A. , Demchenko Alexei V. 
Published: November 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Three New Diterpenoid Alkaloids from Roots of Aconitum ouvrardianum Hand.‐Mazz.
Authors: Hou Lang‐Huan , Chen Dong‐Lin , Jian Xi‐Xian , Wang Feng‐Peng 
Published: November 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Isoquinoline Alkaloids from Corydalis taliensis.
Authors: Wu Ying‐Rui , Zhao You‐Xing , Liu Yu‐Qing , Zhou Jun 
Published: November 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Fusapyridons A and B, Novel Pyridone Alkaloids from an Endophytic Fungus, Fusarium sp. YG‐45.
Authors: Tsuchinari Mio , Shimanuki Keiko , Hiramatsu Fuminori , Murayama Tetsuya , Koseki Takuya , Shiono Yoshihito 
Published: November 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
A Structure and an Absolute Configuration of (+)‐Alternamin, a New Coumarin from Murraya alternans Having Antidote Activity Against Snake Venom.
Authors: Min Hla Myoe , Aye Mya , Taniguchi Tohru , Miura Nobuaki , Monde Kenji , Ohzawa Kazuhiko , Nikai Toshiaki , Niwa Masatake , Takaya Yoshiaki 
Published: November 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Malonyl‐4,5‐dihydroniphimycin: A New Polyol Macrolide Antibiotic, Produced by Streptomyces hygroscopicus.
Authors: Ivanova Veneta , Kolarova Mariana , Aleksieva Krasja 
Published: November 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Synthesis of the anti‐Helicobacter pylori Agent (+)‐Spirolaxine Methyl Ether (Ia) and the Unnatural (2′′S)‐Diastereomer (Ib).
Authors: Robinson James E. , Brimble Margaret A. 
Published: November 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Formation of Direct Metal—Metal Bonds from 16‐Electron “Pseudoaromatic” Half‐Sandwich Complexes Cp“M[E2C2(B10H10)]
Authors: Liu Shuang , Han Ying‐Feng , Jin Guo‐Xin 
Published: November 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Luminescent Complexes with Ligands Containing C=N Bond
Authors: Metelitsa A. V. , Burlov A. S. , Bezuglyi S. O. , Borodkina I. G. , Bren V. A. , Garnovskii A. D. , Minkin V. I. 
Published: November 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Ionic Fullerene Compounds Containing Negatively Charged Dimers and Coordinatively Bound Anions
Authors: Konarev D. V. , Khasanov S. S. , Lyubovskaya R. N. 
Published: November 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Photo‐imageable Sol—Gel Hybrid Materials for Simple Fabrication of Micro‐optical Elements
Authors: Kang Dong Jun , Bae Byeong‐Soo 
Published: November 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Chiral Ligands with an Isoborneol‐10‐sulfonamide Structure: A Ten‐Year Odyssey
Authors: Ramon Diego J. , Yus Miguel 
Published: November 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Cell‐Penetrating Proline‐Rich Peptidomimetics
Authors: Farrera‐Sinfreu Josep , Giralt Ernest , Royo Miriam , Albericio Fernando 
Published: November 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Activation and Inactivation of Hydrogenase Function and the Catalytic Cycle: Spectroelectrochemical Studies
Authors: De Lacey Antonio L. , Fernandez Victor M. , Rousset Marc , Cammack Richard 
Published: November 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Development of Integrase Inhibitors for Treatment of AIDS: An Overview.
Authors: Dubey Sonal , Satyanarayana Y. D. , Lavania Harshita 
Published: November 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Overcoming the Inadequacies or Limitations of Experimental Structures as Drug Targets by Using Computational Modeling Tools and Molecular Dynamics Simulations
Authors: Marco Esther , Gago Federico 
Published: November 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Adjuvant therapy for pancreatic cancer
Authors: Zuckerman Dan S. , Ryan David P. 
Published: November 2007

AbstractPancreatic cancer is uniformly fatal unless it can be surgically resected. Survival rates for the 15% to 20% of patients who have resectable disease, however, are a disappointing 10% to 30%, depending on the status of margins and surrounding lymph nodes. In the mid‐1980s, a landmark study by the Gastrointestinal Tumor Study Group was the first to demonstrate a survival benefit from adjuvant therapy in the form of chemoradiation. Since then, several studies in both North America and Europe have tested the role of adjuvant chemotherapy or chemoradiation in pancreatic cancer, and the results have stirred great controversy. For this review, the evidence for adjuvant therapy in pancreatic cancer was examined, and the significant practice differences that exist between North American and European oncologists were highlighted. The authors investigated the results from the European Study Group for Pancreatic Cancer‐1 trial and the reasons why that study has served to reinforce rather than resolve these trans‐Atlantic differences. They also reviewed preliminary data from more recent adjuvant trials and explored the possible benefits of a neoadjuvant approach. Cancer 2008. © 2007 American Cancer Society.
Anisotropic smoothness spaces via level sets
Authors: DeVore Ronald A. , Petrova Guergana , Wojtaszczyk Przemysław 
Published: November 2007

AbstractIt has been understood for sometime that the classical smoothness spaces, such as the Sobolev and Besov classes, are not satisfactory for certain problems in image processing and nonlinear PDEs. Their deficiency lies in their isotropy. Functions in these smoothness spaces must be simultaneously smooth in all directions. The anisotropic generalizations of these spaces also have the deficiency that they are biased in coordinate directions. While they allow different smoothness in certain directions, these directions must be aligned to the coordinate axes. In the application areas mentioned above, it would be desirable to measure smoothness in new ways that would allow one to have more local control over the smoothness directions. We introduce one possible approach to this problem based on defining smoothness via level sets. We present this approach in the case of functions defined on ℝd. Our smoothness spaces depend on two smoothness indices (s1, s2). The first reflects the smoothness of the level sets of the function, while the second index reflects how smoothly the level sets themselves are changing. As a motivation, we start with d = 2 and investigate Besov smooth domains. © 2007 Wiley Periodicals, Inc.
Requirement of secondary lymphoid tissues for the induction of primary and secondary T cell responses against Listeria monocytogenes
Authors: Kursar Mischo , Jänner Nathalie , Pfeffer Klaus , Brinkmann Volker , Kaufmann Stefan H. E. , Mittrücker Hans‐Willi 
Published: November 2007

AbstractActivation of naive T cells is tightly controlled and depends on cognate interactions with professional antigen‐presenting cells. We analyzed dependency on secondary lymphoid tissues for the activation of naive and memory CD4+ and CD8+ T cells following primary and secondary Listeria monocytogenes infection, respectively. In splenectomized lymphotoxin‐β receptor‐deficient mice, lacking all secondary lymphoid tissues, oral infection with L. monocytogenes failed to induce bacteria‐specific CD4+ and CD8+ T cell responses. Treatment of splenectomized wild‐type mice with FTY720, a drug that prevents egress of T cells from lymph nodes, also reduced T cell responses after oral L. monocytogenes infection and blocked T cell responses after intravenous infection. FTY720‐treated wild‐type and lymphotoxin‐β receptor‐deficient mice show only slightly impaired recall responses. However, T cell responses were profoundly inhibited when mice were splenectomized subsequently to recovery from primary infection. T cell transfer experiments demonstrated that the impaired secondary T cell response was not simply due to removal of a large fraction of memory T cells by splenectomy. Overall, these results indicate that not only primary T cell responses, but also secondary T cell responses, highly depend on the lymphoid environment for effective activation.
Expression of PI(4,5)P2‐binding proteins lowers the PI(4,5)P2 level and inhibits FcγRIIA‐mediated cell spreading and phagocytosis
Authors: Szymańska Ewelina , Sobota Andrzej , Czuryło Edward , Kwiatkowska Katarzyna 
Published: November 2007

AbstractWe found that FcγRII‐mediated cell spreading and phagocytosis were correlated with an increase of phosphatidylinositol 4,5‐bisphosphate [PI(4,5)P2] level in cells. During the spreading, a long‐lasting elevation of PI(4,5)P2 and concomitant actin polymerization occurred. Filopodia and lamellae of spreading cells were enriched in phosphatidylinositol 4‐phosphate 5‐kinase Iα (PIP5‐kinase Iα) that colocalized with PI(4,5)P2 and actin filaments. Both spreading and phagocytosis were inhibited by expression of the C374–440 fragment of PIP5‐kinase Iα or the pleckstrin homology domain of phospholipase Cδ1 (PLCδ1‐PH), two probes binding PI(4,5)P2. These probes reduced the amount of PI(4,5)P2 in the cells, evoked reorganization of the actin cytoskeleton and abolished PI(4,5)P2 elevation during phagocytosis. Simultaneously, PLCδ1‐PH‐GFP reduced the amount of PIP5‐kinase Iα associated with the plasma membrane. In vitro studies demonstrated that PIP5‐kinase Iα‐GST bound PI(4,5)P2, phosphatidylinositol 4‐monophosphate, and less efficiently, phosphatidic acid. The data suggest that the PLCδ1‐PH domain, and possibly also the C374–440 fragment, when expressed in cells, can compete with endogenous PIP5‐kinase Iα for PI(4,5)P2 binding in the plasma membrane leading eventually to PI(4,5)P2 depletion.
Meldola's Blue Immobilized on a SiO2/SnO2/Phosphate Xerogel, a New Sensor for Determination of Ascorbic Acid in Medicine and Commercial Fruit Juice
Authors: de Castilho Rodrigo Ferrari , de Souza Eloana Benassi Ribeiro , da Silva Alfaya Rení Ventura , da Silva Alfaya Antonio Alberto 
Published: November 2007

AbstractA modified carbon paste electrode with SiO2/SnO2/Phosphate/Meldola's blue, SSPMelB, was used to study the electrocatalytic oxidation of ascorbic acid by cyclic voltammetry and chronoamperometry. The adsorbed dye mediates ascorbic acid oxidation at an anodic potential of 0.04 V vs. saturated calomel electrode (SCE) at pH 7.0, in 0.5 mol L−1 solution. The linear range of the sensor is between 4.0×10−7 and 2.0×10−3 mol L−1, with a limit of detection of 4.0×10−7 mol L−1. This novel electrode shows good analytical performance for determination of ascorbic acid in medicine and commercial fruit juice.
Osmium Redox Hydrogel Mediated Biosensor for Measurement of Low Concentration Glucose Extracted by Reverse Iontophoresis
Authors: Liu Hongmin , Liu Chunxiu , Jiang Liying , Liu Jian , Yang Qingde , Guo Zonghui , Cai Xinxia 
Published: November 2007

AbstractAn osmium redox hydrogel mediated biosensor for continuous monitoring of glucose extracted from subcutaneous solution by reverse iontophoresis has been developed. For the measurement of low concentration glucose, osmium‐poly(vinylpyridine) wiring horseradish peroxidase was introduced to modify the smooth Au electrodes, and the developed glucose biosensor exhibited a high sensitivity of 11.45 nA μM−1 cm−2 and a low detection limit of 2 μM, as well as a high operational stability of more than 97% of its initial activity over a test period of 13.5 h in stirred glucose solution at low applied potential (−0.1 V vs. Ag|AgCl), efficiently inhibiting the electroactive interferences. Permeability of the hydrogels was studied and a diffusion coefficient of 2.4×10−5 cm2/s for H2O2 was obtained. In addition, the effects, such as temperature and the variation happening on Ag|AgCl counter electrode, on determination of glucose were also considered. The proof‐of‐feasibility of the biosensors for the monitoring of the glucose extracted from the subcutaneous solution was tested in vitro, and the responses of the sensors were analyzed. A linear response to current produced by extracted glucose in the concentration range of subcutaneous glucose from 1.0 to 12 mM was obtained with a correlation coefficient up to 0.989. These results testify the feasibility of the developed sensors for measuring the low concentration glucose and have significance for the development of noninvasive glucose monitoring system for the control of diabetes.
Coarse Grained Molecular Dynamics Simulation of Electromechanically‐Gated DNA Modified Conical Nanopores
Authors: Höfler Lajos , Gyurcsányi Róbert E. 
Published: November 2007

AbstractNanopore‐based devices are emerging as tools for single molecule manipulation, characterization and chemical analysis. Single or random arrays of chemically modified nanopores have been established as platforms for selective chemical and biosensing. However, it is little known about the orientation and behavior of surface tethered species in the nanopore environment as function of applied transpore voltages. In this study we report on coarse grained modeling of short (5‐, 15‐mer) DNA modified conical gold nanopores subjected to electrical field gradients of 5 and 50 mV/nm. An electromechanical gating effect in the single stranded DNA modified conical nanopores is predicted, which is due to the obstruction of the tip entrance by DNA strands oriented by the external electrical field. The magnitude of the rectification effect increases with increasing DNA length and decreasing tip diameter of the conical nanopore. The direction of on/off switching was found to be dependent on the location of the immobilized DNAs on the membrane supporting the nanopore.
Novel Polymeric Membrane Sensors Based on Mn(III) Porphyrin and Co(II) Phthalocyanine Ionophores for Batch and Flow Injection Determination of Azide
Authors: Hassan Saad S. M. , Kelany Ali E. , Al‐Mehrezi Saeed S. 
Published: November 2007

AbstractTwo novel potentiometric azide membrane sensors based on the use of manganese(III)porphyrin [Mn(III)P] and cobalt(II)phthalocyanine [Co(II)Pc] ionophores dispersed in plasticized poly(vinyl chloride) PVC matrix membranes are described. Under batch mode of operation, [Mn(III)P] and [Co(II)Pc] based membrane sensors display near‐ and sub‐Nernstian responses of −56.3 and −48.5 mV decade−1 over the concentration ranges 1.0×10−2−2.2×10−5 and 1.0×10−2−5.1×10−5 mol L−1 azide and detection limits of 1.5×10−5 and 2.5×10−5 mol L−1, respectively. Incorporation of both membrane sensors in flow‐through tubular cell offers sensitive detectors for flow injection (FIA) determination of azide. The intrinsic characteristics of the [Mn(III)P] and [Co(II)Pc] based detectors in a low dispersion manifold show calibration slopes of −51.2 and −33.5 mV decade−1 for the concentration ranges of 1.0×10−5−1.0×10−2 and 1.0×10−4−1.0×10−2 mol L−1 azide and the detection limits are1.0×10−5 and 3.1×10−5 mol L−1, respectively. The detectors are used for determining azide at an input rate of 40–60 samples per hour. The responses of the sensors are stable within ±0.9 mV for at least 8 weeks and are pH independent in the range of 3.9−6.5. No interferences are caused by most common anions normally associated with azide ion.
Composite Assembly of Silver Nanoparticles with Avidin and Biotinylated AChE on Gold for the Pesticidal Electrochemical Sensing
Authors: Huang Xi , Du Dan , Gong Xiaojuan , Cai Jie , Tu Haiyang , Xu Xing , Zhang Aidong 
Published: November 2007

AbstractAn amperometric pesticide biosensor has been devised by the composite assembly of silver nanoparticles with avidin and biotinylated acetylcholinesterase (AChE) on gold electrodes modified with a biotin‐terminated self assembly monolayer (SAM). This composite assembly strategy takes use of the biospecific recognition avidin with the biotin from the SAM‐terminals and biotinylated AChE, as well as the electrostatic interaction between silver nanoparticles with negatively charged citrate shell and avidin with encounter charge at pH 7.2. The construction process of the composite interface on gold was monitored by surface plasmon resonance (SPR), and its structure was characterized by attenuated total reflection Fourier‐transform infrared spectra, atomic force microscopy and UV‐vis spectra. The composite interface shows excellent electron transfer ability, as characterized by cyclic voltammetry and electrochemical impedance spectroscopy. Under the optimum conditions a quantitative measurement of organophosphate pesticide dimethoate was achieved with the linear range of 0.05 μM to10 μM and the detection limit 0.01 μM, taken as the concentration equivalent to a 10% decrease in signal. Silver nanoparticles conjugated biotin‐avidin system represents a simple and functional approach to the integration of electrode sensing interface with improved biocompatibility and electron transfer ability, which may provide an analytical access to a large group of enzymes for bioelectrochemical application.
Prussian Blue Dispersed Sphere Catalytic Labels for Amplified Electronic Detection of DNA
Authors: Suwansa‐ard Siriwan , Xiang Yun , Bash Ralph , Thavarungkul Panote , Kanatharana Proespichaya , Wang Joseph 
Published: November 2007

AbstractA highly sensitive electrochemical DNA hybridization assay using Prussian blue (PB)‐modified polymeric spheres as the oligonculeotide labeling tag is described. The sandwich assay relies on a secondary nucleic‐acid probe functionalized with polystyrene beads loaded with numerous Prussian blue nanoparticles. The very strong catalytic activity of the captured PB ‘artificial peroxidase’ tag towards the reduction of hydrogen peroxide, along with the encapsulation of numerous catalytic particles onto polymeric beads, allows amperometric detection of the DNA target down to the 50 fM level (2.5 amol). Imaging and spectroscopic measurements are used to characterize the PB‐tagged polystyrene beads. Such coupling of PB catalytic labels with polymeric carrier beads offers great promise for amplified transduction of different biomolecular interactions.