bluuebunny/crossref_metadata_2025_split huggingface dataset:
Behaviors and influencing factors of Chinese oncology nurses towards hospice care: a cross-sectional study based on social cognitive theory in 2022
Authors: Zhao Jing , Wang Yu , Xiao Binbin , Ye Fucheng , Chen Jianfei , Huang Yingjuan , Li Ting , Chen Xiaoli , Ma Hongmei , Zhang Qing , Zou Zhijie 
Published: February 2024

Abstract
Background
Although there is growing demand for hospice care in China due to its aging population and increasing cancer rates, the sector remains slow to expand. Oncology nurses are the primary providers of hospice care, but little is known about their behaviors towards hospice care and related factors.

Methods
This cross-sectional study conveniently sampled 933 oncology nurses from six grade A tertiary hospitals in Hubei Province between January to March 2022. The questionnaire was composed of seven parts: general information (including sociodemographic and work-related information), hospice care behaviors, hospice care knowledge, hospice care attitudes, hospice care self-efficacy, hospice care outcome expectancy, and hospice care environment. Data were analyzed using descriptive analysis, independent sample t-tests, one-way ANOVA, Pearson’s correlation, multiple linear regression, random forest regression, and BP neural network model analysis.

Results
A total of 852 questionnaires were valid. The mean score of hospice care behaviors was 50.47 ± 10.56, with a mean item score of 3.61 ± 0.75. The three highest scoring behaviors were “pain assessment of patients (4.21 ± 0.91)”, “satisfying the physical and mental needs of dying patients (4.04 ± 0.92)”, and “creating good relationships between the medical staff and family members (4.02 ± 0.87)”. The two lowest-scoring behaviors were “proactively recommending medical institutions for hospice care to terminally ill patients and their families (2.55 ± 1.10)” and “proactively talking to patients and families about death-related topics for patients who are critically ill and cannot be reversed (2.87 ± 1.03).” Multiple linear regression, random forest regression, and BP neural network models all showed that the frequency of sharing hospice care experiences with colleagues, hospice care attitudes, hospice care self-efficacy, and hospice care environments were positively associated with hospice care behaviors.

Conclusions
The frequency of hospice care behaviors among Chinese oncology nurses is generally at a moderate to high level. The results provide a basis for promoting hospice care behaviors among oncology nurses in order to improve the quality of life for terminally ill cancer patients.
Endothelial and mural laminin-α5 contributes to neurovascular integrity maintenance
Authors: Nirwane Abhijit , Kang Minkyung , Adithan Aravinthan , Maharaj Vrishni , Nguyen Felicia , Santaella Aguilar Elliot , Nasrollahi Ava , Yao Yao 
Published: February 2024

Abstract
Background
Laminin-α5, a major component of the basal lamina, is predominantly synthesized by endothelial and mural cells (pericytes and vascular smooth muscle cells) in the CNS. Loss of laminin-α5 in either population fails to induce any abnormalities due to functional redundancy. Thus, the functional significance of laminin-α5 in neurovascular integrity remains unknown. Here, we hypothesize that ablation of laminin-α5 in both endothelial and mural cells increases neurovascular permeability.

Methods
The compound knockout mice were generated by crossing laminin-α5 floxed mice with Tie2-Cre and PDGFRβ-Cre, which target endothelial cells and mural cells, respectively. Neurovascular permeability in these mutants was determined with both exogenous and endogenous tracers. Endothelial paracellular and transcellular permeability was assessed by examining the expression of tight junction proteins and transcytosis-associated proteins. In addition, transmission electron microscopy (TEM) was used to visualize tight junction ultrastructure and endothelial caveolae vesicles. Defects in pericytes and astrocytes were investigated by examining pericyte coverage/contact and astrocyte polarity.

Results
Elevated neurovascular permeability was observed in the mutants. Subsequent studies found increased Caveolin-1 and decreased major facilitator superfamily domain-containing protein 2a (MFSD2A) expression, but unaltered Claudin-5 or zonula occludens-1 (ZO-1) expression. Consistent with these results, mutant mice exhibited increased endothelial caveolae vesicle number with intact tight junction structure under TEM. Additionally, pericyte coverage and contact were also decreased in the mutant mice, while astrocyte polarity was unaffected.

Conclusions
These results strongly indicate that endothelial and mural cell-derived laminin-α5 actively maintains neurovascular integrity via the transcellular rather than paracellular mechanism.
Exploration of genes encoding KEGG pathway enzymes in rhizospheric microbiome of the wild plant Abutilon fruticosum
Authors: Abulfaraj Aala A. , Shami Ashwag Y. , Alotaibi Nahaa M. , Alomran Maryam M. , Aloufi Abeer S. , Al-Andal Abeer , AlHamdan Nawwaf R. , Alshehrei Fatimah M. , Sefrji Fatmah O. , Alsaadi Khloud H. , Abuauf Haneen W. , Alshareef Sahar A. , Jalal Rewaa S. 
Published: February 2024

AbstractThe operative mechanisms and advantageous synergies existing between the rhizobiome and the wild plant species Abutilon fruticosum were studied. Within the purview of this scientific study, the reservoir of genes in the rhizobiome, encoding the most highly enriched enzymes, was dominantly constituted by members of phylum Thaumarchaeota within the archaeal kingdom, phylum Proteobacteria within the bacterial kingdom, and the phylum Streptophyta within the eukaryotic kingdom. The ensemble of enzymes encoded through plant exudation exhibited affiliations with 15 crosstalking KEGG (Kyoto Encyclopaedia of Genes and Genomes) pathways. The ultimate goal underlying root exudation, as surmised from the present investigation, was the biosynthesis of saccharides, amino acids, and nucleic acids, which are imperative for the sustenance, propagation, or reproduction of microbial consortia. The symbiotic companionship existing between the wild plant and its associated rhizobiome amplifies the resilience of the microbial community against adverse abiotic stresses, achieved through the orchestration of ABA (abscisic acid) signaling and its cascading downstream effects. Emergent from the process of exudation are pivotal bioactive compounds including ATP, D-ribose, pyruvate, glucose, glutamine, and thiamine diphosphate. In conclusion, we hypothesize that future efforts to enhance the growth and productivity of commercially important crop plants under both favorable and unfavorable environmental conditions may focus on manipulating plant rhizobiomes.
An FSCEEMD method for downhole weak SNR signal extraction of near-bit attitude parameters
Authors: Mao Yanhui , Yang Longhan , Huo Aiqing , Li Fei , Gao Yi 
Published: February 2024

AbstractIn practice, the near-bit drilling tool confronts with strong vibrations and high-speed rotation. Therein the original signal amplitude of the tool attitude measurements is relatively feeble, and the signal-to-noise ratio (SNR) is exceptionally low. To handle this issue, this paper proposes a weak SNR signal extraction method, frequency selecting complementary ensemble empirical mode decomposition, which is based on ensemble empirical mode decomposition combining with complementary noise and frequency selecting. This method firstly adds different positive and negative pairs of auxiliary white noise to the original near-bit weak SNR signal, secondly adopts empirical mode decomposition on each pair of noise-added signals, then performs ensemble averaging on the obtained multiple sets of intrinsic mode function (IMF) to output more stable IMF of each order and set suitable weights according to designed frequency threshold, and finally reconstructs the original useful signal through weighted summing IMFs. Simulation results show that the extraction accuracy of well inclination angle ranges about ± 0.51°, and the extraction accuracy of tool face angle ranges about ± 1.35°, and meanwhile experimental results are provided compared with other advanced methods, which verifies the effectiveness of our method.
Views of German mental health professionals on the use of digital mental health interventions for eating disorders: a qualitative interview study
Authors: Mayer Gwendolyn , Lemmer Diana , Michelsen Ina , Schrader Pauline , Friederich Hans-Christoph , Bauer Stephanie 
Published: February 2024

Abstract
Introduction
Digital mental health interventions (DMHIs) are getting increasingly important for mental health care. In the case of eating disorders (EDs), DMHIs are still in early stages. Few studies so far investigated the views of mental health professionals for EDs on the integration of DMHIs in routine care.

Objective
To gain insights into the experiences, perspectives, and expectations of mental health professionals for EDs regarding DMHIs and to identify requirements for the future integration of DMHIs into routine care.

Methods
Semi-structured qualitative telephone interviews with 24 German mental health professionals treating patients with EDs were conducted. A content analysis following a deductive-inductive approach asked for experiences, advantages and chances, disadvantages and boundaries, desired functions and properties, target groups, and general conditions and requirements for DMHIs for patients with EDs.

Results
Only few professionals reported experiences with DMHIs besides video-based psychotherapy during the pandemic. From the therapists’ point of view, DMHIs have the potential to deliver low-threshold access for patients with EDs. Useful functionalities were seen in digital meal records, skills training, and psychoeducation. However, a stable therapeutic alliance was reported as an important prerequisite for the successful integration into care. Therapists expressed concerns in case of severe anorexia nervosa or suicidality. The participants felt to be informed inadequately on recent developments and on the evidence base of DMHIs.

Conclusions
Mental health professionals for EDs show positive attitudes towards DMHIs, however many barriers to the integration in routine care were observed. The highest potential was seen for the use of DMHIs in addition to outpatient care and in aftercare. Specific requirements for DMHIs are related to different areas of the healthcare spectrum and for the different symptom profiles in anorexia nervosa, bulimia nervosa and binge eating disorder. Targeted DMHIs are needed and appropriate especially for concepts of blended care.
Assessing the efficacy of the ‘Bicho De 7 Cabeças’ B-learning school-based program in enhancing mental health literacy and reducing stigma
Authors: Meilsmeidth Gislene , Trigueiro Maria João , Simões-Silva Vítor , Simões de Almeida Raquel , Portugal Paula , Gomes Paulo Veloso , de Sousa Sara , Campos Filipa , Monteiro Pedro , Soutelo Ana Paula , Marques António 
Published: February 2024

AbstractThe prevalence of mental disorders in adolescents has a considerable impact on daily life, restricting tasks and diminishing overall quality of life while potentially leading to stigmatization. This study aims to measure the impact of a mental health literacy intervention program, called “Bicho de 7 Cabeças” project, in b-learning format, on the increase of knowledge and the decrease of stigma in young people from Póvoa de Varzim, in Portugal. A quasi-experimental study was conducted, from November 2022 to May 2023, involving an experimental group (“Bicho de 7 Cabeças” protocol) and an active control group (informational brochures), utilizing a pre-test/post-test design. Mental Health Literacy Measure-MHLM, Mental Health Promoting Knowledge Scale-MHPK-10, Mental Illness Knowledge Schedule-MAKS, Reported and Intended Behaviour Scale-RIBS, and Community Attitudes toward People with Mental Illness-CAMI were used. A total of 504 young students from the 9th grade enroll in this study, with a mean age around 14 years old. There is a significant difference between stigma (p <.001) and knowledge (p <.001) scores at baseline and follow-up. The results of this study shows that interventions aimed at young people for the promotion of mental health literacy and stigma reduction are needed and more initiatives should be implemented in schools to address these problems.
An investigation of the on-board microwave radiometer of satellite Altimetry for studying the atmosphere variability
Authors: Abdullah Noor Nabilah , Wijaya Dudy Darmawan , Meilano Irwan , Kuntjoro Wedyanto , Tanuwijaya Zamzam Akhmad Jamaluddin , Abdillah Muhammad Rais , Nurzaman Fathin 
Published: February 2024

AbstractSince its first launching, the ability of satellite Altimetry in providing reliable and accurate ocean geophysical information of the sea surface height (SSH), significant wave height (SWH), and wind speed has been proven by numerous researchers, as it was designed for observing the ocean dynamics through nadir range measurement between satellite and the sea surface. However, to achieve high level accuracy, environmental and geophysical effects on the range measurement must be accurately determined and corrected, particularly the effects from the atmospheric water vapor which can divert altimeter range up to 3–45 cm. Thus, satellite Altimetry is originally equipped with the on-board microwave radiometer to measure the water vapour content for correcting the range measurement. To our knowledge, no one has attempted to apply the on-board radiometer for atmospheric studies. In this present work, we attempt to optimize the on-board radiometer data for studying the atmosphere variability due to the El Niño–Southern Oscillation (ENSO) phenomena. We convert the on-board water vapor data into the precipitable water vapour (PWV), and we then investigate whether the derived PWV can capture the variability of ocean–atmosphere phenomena due to ENSO as accurate as the conventional Altimetry-derived sea level anomaly (SLA). Based on our analysis using the empirical orthogonal function (EOF), the results show convincing argument that Altimetry-derived PWV are reliable in examining the atmospheric fluctuation as the correlation of its primary principal component time series (PC1) with Oceanic Nino Index (ONI) is higher (0.87) than SLA (0.80). These results may reinforce the confidence in the ability of satellite Altimetry for ocean–atmospheric studies.
Graphical Abstract
Cataract progression after primary pars plana vitrectomy for uncomplicated rhegmatogenous retinal detachments in young adults
Authors: Kasetty Venkatkrish M. , Monsalve Pedro F. , Sethi Dhruv , Yousif Candice , Hessburg Thomas , Kumar Nitin , Hamad Abdualrahman E. , Desai Uday R. 
Published: February 2024

Abstract
Background
Scleral buckling is typically implemented to repair rhegmatogenous retinal detachments (RRD) in young patients. Therefore, there is limited data on post-pars plana vitrectomy (PPV) cataract formation in this cohort. We report the rates and risk factors of cataract progression after PPV for RRD repair in young eyes.

Methods
Retrospective single-center cohort study. Medical records of patients between the ages of 15 to 45 undergoing PPV for uncomplicated RRD between 2014 and 2020 were reviewed.

Results
Twenty-eight eyes from 26 patients met inclusion criteria. Cataracts developed in 20/28 (71%) eyes after PPV. After PPV, nuclear sclerotic cataract (NSC) rates were higher in patients above 35 (65%) compared to below 35 years (18%) (p = 0.024). Cataracts developed more frequently after macula-off RRDs (88%) compared to macula-on RRDs (50%) (p = 0.044) with NSC more common in macula-off detachments (p = 0.020). At postoperative month 2, all eyes with C3F8 gas developed cataracts compared to 59% of eyes with no gas (p = 0.040).

Conclusions
Cataract formation was common and frequent after PPV. After PPV, young eyes and macula-on detachments developed cataracts less frequently than older eyes and macula-off detachments. If appropriate, a shorter acting gas tamponade should be considered in young eyes to minimize cataract formation.
A large type I right pulmonary artery to left atrium fistula: underwent successful percutaneous device closure with duct occluder—a rare case report
Authors: Vinothkumar S. P. , Mandava Satya Sahitya , Mallick Abhishek , Singhal Manphool , Rohit Manoj Kumar 
Published: February 2024

Abstract
Background
Pulmonary artery to left atrium fistula is an unusual structural cause of silent cyanosis. Only less than 100 cases have been reported so far. A high index of clinical suspicion and proper evaluation with bubble contrast echocardiography and cardiac computed tomography (CT) will help to detect this treatable anomaly. The advent of safer percutaneous closure methods has replaced the need for more invasive surgical closure.

Case presentation
We report an adolescent boy, who presented with long-standing cyanosis and progressive dyspnea with normal clinical cardiovascular examination. On evaluation, echocardiography and bubble contrast study revealed a large right pulmonary artery (RPA) to left atrium (LA) fistula. Cardiac CT confirmed the same with normal pulmonary venous drainage s/o a large 20 mm Type I RPA LA Fistula. He underwent successful percutaneous closure of the fistula tract with a 22 × 24 mm Cera™ duct occluder via transseptal approach uneventfully.

Conclusion
Our case enlightens the methodological approach to diagnosing this rare anomaly as well as the feasibility of percutaneous intervention in such cases as it is one of the largest fistula tracts closed percutaneously to date.
Takotsubo cardiomyopathy in India and its electrocardiography (ECG) comparison to myocardial infarction
Authors: Mishra Tanisha , Saha Rijushree , Paramasivam Ganesh 
Published: February 2024

Abstract
Background
Owing to the limited research on Takotsubo Cardiomyopathy (TCM) in Asia, we aim to evaluate in detail the clinical profiles, lab parameters, investigations, and major adverse cardiovascular events (MACE) seen in patients with TCM in the Indian subcontinent. Additionally, we have compared the electrocardiographic findings of patients with TCM to those of patients with myocardial infarction (MI).

Results
The average age of the patients affected was found to be 60 ± 11 years. Women (87.5%) and patients with hypertension (40%) were found to be at an increased risk of developing the syndrome. The most common presenting symptom was dyspnea (48%) following a trigger most commonly emotional (45%). ST elevation and significant T wave inversions were observed in 40% of patients with TCM. Echocardiography revealed a low left ventricular ejection fraction of 43 ± 9%. Coronary angiography was normal in 60%, the rest had mild/subcritical stenoses. The 6-month MACE was 20% and the mortality rate was 7.5%. Follow-up echocardiography of patients with TCM showed improvement in EF in 75% patients.

Conclusions
TCM was majorly seen in postmenopausal women following an emotional trigger, but a variety of other triggers were noted. T-wave inversions in TCM follow a diffuse pattern in contrast to specific leads seen in MI. Normal or subcritical stenosis in coronaries at presentation, along with a low EF which improves on follow up provide greater evidence for the diagnosis of TCM.
Validity of ductus arteriosus indices added to other ultrasound and Doppler parameters as markers of fetal lung maturity in pregnancy-induced hypertension
Authors: Sayed Safia Badr , Hamed Soha Talaat , Gaafar Hassan Mostafa , Ibrahim Kareman Hamza , Louis Mariam Raafat 
Published: February 2024

Abstract
Aim of work
To determine the relationship between the gestational age and the (PSV, RI and PI) of the ductus arteriosus and lung maturity and to determine the effect of pregnancy-induced hypertension on these parameters.

Material and methods
A prospective cohort study was carried out, in which 90 pregnant women at gestational age 34–40 weeks were selected, 50 as a control and 40 with pregnancy-induced hypertension (PIH). They underwent measurement of ductus arteriosus (DA) (PSV, RI and PI) and observing the percentage of the development of neonatal RDS in control and PIH cases.

Results
There was a direct correlation between the PSV, PI, RI of ductus arteriosus and development of neonatal RDS. A cutoff value for GA, PSV, RI and PI for prediction of the subsequent development of RDS was determined in control ((35.7, 89.9, 0.80, 2.14), with sensitivity (71.4, 100, 85.7, 85.7%) and specificity (93, 97.7, 97.7, 93%), respectively), and PIH (35.7, 91.1, 0.80, 2.14), with sensitivity (71.4, 100, 85.7, 100%) and specificity (71.7, 100, 85.7, 100%), respectively).

Conclusions
We concluded from our study that for the detection of fetal lung maturity in fetuses of GA from 34 to 40 weeks, it is better to combine GA, PSV, RI and PI of DA to detect lung maturity in control and PIH groups to get more accurate results.
Development of an Artificial Intelligence–Based Image Recognition System for Time-Sequence Analysis of Tracheal Intubation
Authors: Wu Yu-Hwa , Huang Kun-Yi , Tseng Alex Chia-Chih 
Published: February 2024

BACKGROUND:
Total intubation time (TIT) is an objective indicator of tracheal intubation (TI) difficulties. However, large variations in TIT because of diverse initial and end targets make it difficult to compare studies. A video laryngoscope (VLS) can capture images during the TI process. By using artificial intelligence (AI) to detect airway structures, the start and end points can be freely selected, thus eliminating the inconsistencies. Further deconstructing the process and establishing time-sequence analysis may aid in gaining further understanding of the TI process.

METHODS:
We developed a time-sequencing system for analyzing TI performed using a #3 Macintosh VLS. This system was established and validated on 30 easy TIs performed by specialists and validated using TI videos performed by a postgraduate-year (PGY) physician. Thirty easy intubation videos were selected from a cohort approved by our institutional review board (B-ER-107-088), and 6 targets were labeled: the lip, epiglottis, laryngopharynx, glottic opening, tube tip, and a black line on the endotracheal tube. We used 887 captured images to develop an AI model trained using You Only Look Once, Version 3 (YOLOv3). Seven cut points were selected for phase division. Seven experts selected the cut points. The expert cut points were used to validate the AI-identified cut points and time-sequence data. After the removal of the tube tip and laryngopharynx images, the durations between 5 identical cut points and sequentially identified the durations of 4 intubation phases, as well as TIT.

RESULTS:
The average and total losses approached 0 within 150 cycles of model training for target identification. The identification rate for all cut points was 92.4% (194 of 210), which increased to 99.4% (179 of 180) after the removal of the tube tip target. The 4 phase durations and TIT calculated by the AI model and those from the expert exhibited strong Pearson correlation (phase I, r = 0.914; phase II, r = 0.868; phase III, r = 0.964; and phase IV, r = 0.949; TIT, r = 0.99; all P < .001). Similar findings were obtained for the PGY’s observations (r > 0.95; P < .01).

CONCLUSIONS:
YOLOv3 is a powerful tool for analyzing images recorded by VLS. By using AI to detect the airway structures, the start and end points can be freely selected, resolving the heterogeneity resulting from the inconsistencies in the TIT cut points across studies. Time-sequence analysis involving the deconstruction of VLS-recorded TI images into several phases should be conducted in further TI research.