bluuebunny/crossref_metadata_2025_split huggingface dataset:
Cambrian orogeny in the Ribeira Belt (SE Brazil) and correlations within West Gondwana: ties that bind underwater
Authors: Schmitt R. S. , Trouw R. A. J. , Van Schmus W. R. , Passchier C. W. 
Published: January 2008

Abstract

A 530–490 Ma tectono-metamorphic event, the Búzios orogeny, is recognized within the Ribeira Belt, along the coast of SE Brazil. Tectonic evolution started with a Late Neoproterozoic marine basin and volcanic activity at
c
. 610 Ma. The rocks in this basin were affected by high-grade metamorphism at
c
. 530 Ma, coeval with deformational phases D
1
–D
2
, which generated compressive low-angle tectonic structures with top-to-NW tectonic transport. Large recumbent folds with NW–SE axes parallel to the main stretching lineation formed during D
3
as the Cabo Frio tectonic domain, the focus of this study, collided with the Oriental terrane to the NW. D
4
sub-vertical shear zones are limited in extent. A new U–Pb age of 501±6 Ma is reported for zircon from an amphibolite-facies shear zone related to either D
3
or D
4
. Post-tectonic 440 Ma pegmatites mark the final stage of tectono-magmatic activity. The Cabo Frio tectonic domain has African affinities and is exotic to the Ribeira Belt. Middle Cambrian deformational and metamorphic ages are also reported from the ‘Angolan’ Pan-African belt, the southern Kaoko and Damara belts in Namibia, and the Cuchilla Dionisio–Punta Del Este terrane in Uruguay. The occurrence of Cambrian metamorphic rocks along the present African and South American coastlines shows that Mesozoic rifting closely follows Palaeozoic sutures of West Gondwana.
Correlations between the classic Paraná and Cape–Karoo sequences of South America and southern Africa and their basin infills flanking the Gondwanides: du Toit revisited
Authors: Milani E. J. , De Wit M. J. 
Published: January 2008

Abstract
Early during the twentieth Century, pioneering correlations between the Palaeozoic–Mesozoic basins of South America and southern Africa were used by Alexander du Toit to support the initial concepts of continental drift and the proposal of a united Gondwana continent. New stratigraphic tools and data can now be used to further tease out similarities and differences to reconstruct the detailed histories of these, the Paraná and Cape–Karoo basins. In turn this knowledge can be used also to increase our understanding of the origin and evolution of Gondwana. Recent advances in tectonics and stratigraphy showed that both basins evolved together along a common early Palaeozoic Gondwana margin facing the Panthalassa. Thereafter, this margin was transformed into a series of linked foreland basins coupled to the evolution of the Gondwanides. In detail, the foreland successions differ considerably due to spatial and temporal differences in tectonic histories along the Gondwanides. Only towards the end of the Palaeozoic did both basins evolve and merge into a single continental-scale, and truly intracratonic, terrestrial Gondwana basin that persisted until the early Cretaceous. This shared history was once again disrupted in the Early Cretaceous during the opening of the South Atlantic Ocean.
Contemporaneous evolution of the Palaeoproterozoic–Mesoproterozoic sedimentary basins of the São Francisco–Congo Craton
Authors: Pedreira A. J. , de Waele B. 
Published: January 2008

Abstract

Deposition of Palaeo–Mesoproterozoic sedimentary rocks on the São Francisco–Congo craton started during Statherian taphrogenesis (1.8–1.75 Ga), as verified by ages of
c
. 1.7 Ga determined for volcanic rocks of the lower part of the Espinhaço Supergroup in the states of Minas Gerais and Bahia (Brazil). These basins contain volcanic rocks and conglomerates alternating with sandstones, argillites and dolomites, deposited in continental, transitional and marine environments. The rocks in the westernmost sector of the Congo Craton (Central Africa) compose the Chela Group, comprising sandstones, argillites and dolomites. In the easternmost region of the Congo Craton the Kibaran, Akanyaru, Kagera and Muva supergroups occur: the first three in the Kibaran Belt and the last in the Irumide Belt and on the Bangweulu Block. They consist predominantly of pelites and schists, sandstones and, in lesser proportion, conglomerates, deposited in shallow marine, fluvial and lacustrine environments. Their sedimentation ages are constrained through ages on felsic tuff layers as follows: Chela Group 1790±17 Ma, Kagera Supergroup 1780 ± 9 Ma, and Muva Supergroup 1879±13 Ma. These data show that broadly coeval and sedimentologically similar epi-continental sedimentary basins occurred on the São Francisco and Congo cratons, suggesting the possible existence of a long-lived wide epi-continental sea covering large areas of these cratons during Statherian times.
Comparisons between the northwestern Borborema Province, NE Brazil, and the southwestern Pharusian Dahomey Belt, SW Central Africa
Authors: dos Santos T. J. S. , Fetter A. H. , Neto J. A. N. 
Published: January 2008

Abstract

Geological and geochronological data for the northwestern part of the Brasiliano Borborema Province are described and compared with their counterparts in the Pan-African Dahomey (Pharusian) belt that flanks the southeastern margin of the West African Craton, where outcrops are sufficiently continuous to discern the nature of the collision during West Gondwana assembly. In the Médio Coreaú domain, NW Borborema Province, U–Pb and Sm–Nd data have revealed unusual basement rocks representing 2.35–2.30 Ga juvenile crust, along with large tracts of 2.15–2.10 Ga juvenile gneisses in the Ceará Central domain. These basement blocks were affected by two pulses of intracratonic extension at 1785 and 775 Ma. Prior to West Gondwana collision, a continental arc (the Santa Quitéria batholith) developed between 665 Ma and 620 Ma. The presence of this arc strengthens the hypothesis that convergence between the Borborema Province and the São Luis craton involved closure of an oceanic basin. New geochronological data are presented showing that Palaeoproterozoic orthogneisses (U–Pb upper intercept 2288±2 Ma) were affected by a major late Neoproterozoic event (554±4 Ma U–Pb lower intercept, 558±3 Ma Sm–Nd whole-rock and mineral isochron). Exhumation and cooling of granulite rocks between 568 and 550 Ma in the Médio Coreaú domain and between
c
. 587 and 576 in the West African Dahomey Belt indicate that the final tectonic phase was not simultaneous along this front of the orogen.
Numerical Simulations of the Formation of Melting-Layer Cloud
Authors: Yasunaga Kazuaki , Hashimoto Akihiro , Yoshizaki Masanori 
Published: January 2008

Abstract
A number of previously published observational studies have reported the common occurrence of cloudy layers at around 5-km elevation in the tropics. There are two candidate processes that are able to explain the occurrence of cloudy layers in the middle level: cloud detrainment promoted by the stable layer and enhanced condensation to compensate for melting cooling. In the present study, the authors used a cloud-resolving nonhydrostatic model and conducted numerical simulations of a squall line to clarify the process responsible for the formation of midlevel thin cloud, especially the cloud at the 0°C level.
In a two-dimensional control experiment thin cloud was simulated in the middle level, and cloud coverage showed a notable peak just below the 0°C level for environments without a stable layer in the initial temperature profile. Enhanced and weakened stability layers simultaneously appeared above and below the peak level of the cloud coverage. The formation of midlevel thin cloud is associated with intensified condensation to compensate for strong cooling due to the melting of ice particles. The enhancement of condensation continues until ice is no longer provided to the cloud at the melting level. This means that the cloud survives for a longer period than cloud at other levels.
To investigate the influence of the commonly observed tropical stable layer on the occurrence of midlevel thin cloud, the authors performed three sensitivity tests in which a warm rain microphysics scheme was employed and/or the initial temperature profile had enhanced and weakened stability layers in the middle level. Comparisons among the control and sensitivity experiments revealed that intensified condensation related to melting cooling plays a critical role in the formation of midlevel thin cloud, although the stable layer is associated with the inhibition of convection growth in the middle level. A three-dimensional experiment under more realistic conditions simulated cloud formation at the 0°C level, although the peak of the cloud coverage was less prominent than those in the two-dimensional experiments.
Anvil Characteristics as Seen by C-POL during the Tropical Warm Pool International Cloud Experiment (TWP-ICE)
Authors: Frederick Kaycee , Schumacher Courtney 
Published: January 2008

Abstract
The Tropical Pacific Warm Pool International Cloud Experiment (TWP-ICE) took place in Darwin, Australia, in early 2006. C-band radar data were used to characterize tropical anvil (i.e., thick, nonprecipitating cloud associated with deep convection) areal coverage, height, and thickness during the monthlong field campaign. The morphology, evolution, and longevity of the anvil were analyzed, as was the relationship of the anvil to the rest of the precipitating system.
The anvil was separated into mixed (i.e., echo base below 6 km) and ice-only categories. The average areal coverage for each anvil type was between 4% and 5% of the radar grid. Ice anvil thickness averaged 2.8 km and mixed anvil thickness averaged 6.7 km. Areal peaks show that mixed anvil typically formed out of the stratiform rain region. Peak production in ice anvil usually followed the mixed anvil peak by 1–3 h. Anvil typically lasted 4–10 h after the initial convective rain area peak. TWP-ICE experienced three distinct regimes: an active monsoon, a dry monsoon, and a break period. During the experiment (except the active monsoon period) there was a strong negative correlation between ice anvil thickness and ice anvil height, a strong positive correlation between ice anvil area and thickness, and a greater variance in ice anvil bottom than ice anvil top. These results have important implications for understanding how anvil affects the tropical atmosphere.
Dynamic Forcing and Mesoscale Variability of Heavy Precipitation Events over the Sierra Nevada Mountains
Authors: Reeves Heather Dawn , Lin Yuh-Lang , Rotunno Richard 
Published: January 2008

Abstract
The aim of this research is to investigate the causes for an isolated maximum in precipitation that is typically found along the northern half of the Sierra Nevada mountains of California, in the vicinity of Plumas National Forest (PNF), during moderate to heavy precipitation events. Particular attention was paid to the role various mesoscale (i.e., &lt;200 km) terrain features may have played in localizing the precipitation at PNF. Numerical simulations and sensitivity experiments for two cases of heavy precipitation at PNF reveal that the extent to which terrain acts to focus precipitation is case sensitive. In the first case, the upstream flow was characterized by a strong horizontal gradient in wind speed and moisture. This gradient led to differential deflection of airstreams incident to the range and, consequently, localized convergence and enhanced rain rates at PNF. This localized enhancement occurred regardless of whether any terrain variations were present in the simulations or not. The second case was characterized by more a horizontally uniform upstream flow and showed a much stronger sensitivity to terrain variations, in particular, short- and long-wavelength undulations along the leading (west) edge of the Sierra Nevada range. When these undulations were removed, no localized maxima in precipitation occurred.
Relationships between Sea Surface Temperatures in the Gulf of California and Surge Events
Authors: Mo Kingtse , Higgins R. W. 
Published: January 2008

Abstract
Relationships between sea surface temperatures (SSTs) in the Gulf of California (GoC) and moisture surge events during the North American Monsoon Experiment (NAME) were examined using the multiplatform-merged daily SST data and the final NCEP North American Regional Reanalysis.
When tropical storms pass through the southern end of the gulf, they often trigger moisture surge events. When surge events pass through the gulf, SSTs in the GoC decrease. Evidence indicates that changes in SSTs in the GoC are caused by the surge events associated with tropical storms.
The intensification of surface winds and changes in humidity and temperature near the surface associated with surge events increase evaporation and decrease the latent heat entering the gulf. Rainfall originating from the peaks and foothills of the Sierra Madre Occidental (SMO) propagates westward into the GoC. Cloudiness increases over the GoC during the surge events, preventing shortwave radiation from reaching the oceanic surface. The net radiation entering the ocean reduces, and less heat into the ocean leads to the cooling of SSTs in the gulf.
Representing Uncertainty in Continental-Scale Gridded Precipitation Fields for Agrometeorological Modeling
Authors: de Wit A. J. W. , de Bruin S. , Torfs P. J. J. F. 
Published: January 2008

AbstractThis work proposes a relatively simple methodology for creating ensembles of precipitation inputs that are consistent with the spatial and temporal scale necessary for regional crop modeling. A high-quality reference precipitation dataset [the European Land Data Assimilation System (ELDAS)] was used as a basis to define the uncertainty in an operational precipitation database [the Crop Growth Monitoring System (CGMS)]. The distributions of precipitation residuals (CGMS − ELDAS) were determined for classes of CGMS precipitation and transformed to a Gaussian distribution using normal score transformations. In cases of zero CGMS precipitation, the occurrence of rainfall was controlled by an indicator variable. The resulting normal-score-transformed precipitation residuals appeared to be approximately multivariate Gaussian and exhibited strong spatial correlation; however, temporal correlation was very weak. An ensemble of 100 precipitation realizations was created based on back-transformed spatially correlated Gaussian residuals and indicator realizations. Quantile–quantile plots of 100 realizations against the ELDAS reference data for selected sites revealed similar distributions (except for the 100th percentile, owing to some large residuals in the realizations). The semivariograms of realizations for sampled days showed considerable variability in the overall variance; the range of the spatial correlation was similar to that of the ELDAS reference dataset. The intermittency characteristics of wet and dry periods were reproduced well for most of the selected sites, but the method failed to reproduce the dry period statistics in semiarid areas (e.g., southern Spain). Finally, a case study demonstrates how rainfall ensembles can be used in operational crop modeling and crop yield forecasting.
Joint Variability of Global Runoff and Global Sea Surface Temperatures
Authors: McCabe Gregory J. , Wolock David M. 
Published: January 2008

Abstract
Global land surface runoff and sea surface temperatures (SST) are analyzed to identify the primary modes of variability of these hydroclimatic data for the period 1905–2002. A monthly water-balance model first is used with global monthly temperature and precipitation data to compute time series of annual gridded runoff for the analysis period. The annual runoff time series data are combined with gridded annual sea surface temperature data, and the combined dataset is subjected to a principal components analysis (PCA) to identify the primary modes of variability. The first three components from the PCA explain 29% of the total variability in the combined runoff/SST dataset. The first component explains 15% of the total variance and primarily represents long-term trends in the data. The long-term trends in SSTs are evident as warming in all of the oceans. The associated long-term trends in runoff suggest increasing flows for parts of North America, South America, Eurasia, and Australia; decreasing runoff is most notable in western Africa. The second principal component explains 9% of the total variance and reflects variability of the El Niño–Southern Oscillation (ENSO) and its associated influence on global annual runoff patterns. The third component explains 5% of the total variance and indicates a response of global annual runoff to variability in North Atlantic SSTs. The association between runoff and North Atlantic SSTs may explain an apparent steplike change in runoff that occurred around 1970 for a number of continental regions.
A Study of the Characteristics and Assimilation of Retrieved MODIS Total Precipitable Water Data in Severe Weather Simulations
Authors: Chen Shu-Hua , Zhao Zhan , Haase Jennifer S. , Chen Aidong , Vandenberghe Francois 
Published: January 2008

Abstract
This study determined the accuracy and biases associated with retrieved Moderate Resolution Imaging Spectroradiometer (MODIS) total precipitable water (TPW) data, and it investigated the impact of these data on severe weather simulations using the Weather Research and Forecast (WRF) model. Comparisons of MODIS TPW with the global positioning system (GPS) TPW and radiosonde-derived TPW were carried out. The comparison with GPS TPW over the United States showed that the root-mean-square (RMS) differences between these two datasets were about 5.2 and 3.3 mm for infrared (IR) and near-infrared (nIR) TPW, respectively. MODIS IR TPW data were overestimated in a dry atmosphere but underestimated in a moist atmosphere, whereas the nIR values were slightly underestimated in a dry atmosphere but overestimated in a moist atmosphere.
Two cases, a severe thunderstorm system (2004) over land and Hurricane Isidore (2002) over ocean, as well as conventional observations and Special Sensor Microwave Imager (SSM/I) retrievals were used to assess the impact of MODIS nIR TPW data on severe weather simulations. The assimilation of MODIS data has a slightly positive impact on the simulated rainfall over Oklahoma for the thunderstorm case, and it was able to enhance Isidore’s intensity when the storm track was reasonably simulated. The use of original and bias-corrected MODIS nIR TPW did not show significant differences from both case studies. In addition, SSM/I data were found to have a positive impact on both severe weather simulations, and the impact was comparable to or slightly better than that of MODIS data.
Lyn regulates BCR-ABL and Gab2 tyrosine phosphorylation and c-Cbl protein stability in imatinib-resistant chronic myelogenous leukemia cells
Authors: Wu Ji , Meng Feng , Lu Henry , Kong Ling , Bornmann William , Peng Zhenghong , Talpaz Moshe , Donato Nicholas J. 
Published: January 2008

Abstract
Lyn kinase functions as a regulator of imatinib sensitivity in chronic myelogenous leukemia (CML) cells through an unknown mechanism. In patients who fail imatinib therapy but have no detectable BCR-ABL kinase mutation, we detected persistently activated Lyn kinase. In imatinib-resistant CML cells and patients, Lyn activation is BCR-ABL independent, it is complexed with the Gab2 and c-Cbl adapter/scaffold proteins, and it mediates persistent Gab2 and BCR-ABL tyrosine phosphorylation in the presence or absence of imatinib. Lyn silencing or inhibition is necessary to suppress Gab2 and BCR-ABL phosphorylation and to recover imatinib activity. Lyn also negatively regulates c-Cbl stability, whereas c-Cbl tyrosine phosphorylation is mediated by BCR-ABL. These results suggest that Lyn exists as a component of the BCR-ABL signaling complex and, in cells with high Lyn expression or activation, BCR-ABL kinase inhibition alone (imatinib) is not sufficient to fully disengage BCR-ABL–mediated signaling and suggests that BCR-ABL and Lyn kinase inhibition are needed to prevent or treat this form of imatinib resistance.
Rank-based edge reconstruction for scale-free genetic regulatory networks
Authors: Chen Guanrao , Larsen Peter , Almasri Eyad , Dai Yang 
Published: January 2008

AbstractBackgroundThe reconstruction of genetic regulatory networks from microarray gene expression data has been a challenging task in bioinformatics. Various approaches to this problem have been proposed, however, they do not take into account the topological characteristics of the targeted networks while reconstructing them.ResultsIn this study, an algorithm that explores the scale-free topology of networks was proposed based on the modification of a rank-based algorithm for network reconstruction. The new algorithm was evaluated with the use of both simulated and microarray gene expression data. The results demonstrated that the proposed algorithm outperforms the original rank-based algorithm. In addition, in comparison with the Bayesian Network approach, the results show that the proposed algorithm gives much better recovery of the underlying network when sample size is much smaller relative to the number of genes.ConclusionThe proposed algorithm is expected to be useful in the reconstruction of biological networks whose degree distributions follow the scale-free topology.
Bioinformatic identification of FGF, p38-MAPK, and calcium signalling pathways associated with carcinoma in situin the urinary bladder
Authors: Herbsleb Malene , Christensen Ole F , Thykjaer Thomas , Wiuf Carsten , Borre Michael , Ørntoft Torben F , Dyrskjøt Lars 
Published: January 2008

Abstract

Background
Carcinoma in situ (CIS) is believed to be a precursor of invasive bladder cancer. Identification of CIS is a valuable prognostic factor since radical treatment strategies can be offered these patients before the disease becomes invasive.

Methods
We developed a pathway based classifier approach to predict presence or absence of CIS in patients suffering from non muscle invasive bladder cancer. From Ingenuity Pathway Analysis we considered four canonical signalling pathways (p38 MAPK, FGF, Calcium, and cAMP pathways) with most coherent expression of transcription factors (TFs) across samples in a set of twenty-eight non muscle invasive bladder carcinomas. These pathways contained twelve TFs in total. We used the expression of the TFs to predict presence or absence of CIS in a Leave-One-Out Cross Validation classification.

Results
We showed that TF expression levels in three pathways (FGF, p38 MAPK, and calcium signalling) or the expression of the twelve TFs together could be used to predict presence or absence of concomitant CIS. A cluster analysis based on expression of the twelve TFs separated the samples in two main clusters: one branch contained 11 of the 15 patients without concomitant CIS and with the majority of the genes being down regulated; the other branch contained 10 of 13 patients with concomitant CIS, and here genes were mostly up regulated. The expression in the CIS group was comparable to the expression of twenty-three patients suffering from muscle-invasive bladder carcinoma. Finally, we validated our results in an independent test set and found that prediction of CIS status was possible using TF expression of the p38 MAPK pathway.

Conclusion
We conclude that it is possible to use pathway analysis for molecular classification of bladder tumors.