bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pendidikan Multikultural Sebagai Sarana Membangun Integritas Bangsa
Authors: Peter Ramot , Simatupang Masda Surti 
Published: March 2024

Indonesia dikenal oleh masyarakat dunia sebagai negara yang kaya akan keberagaman suku, agama, Bahasa dan budaya. Keberagaman yang dimiliki Indonesia merupakan kekayaan yang dianugerahkan oleh Tuhan Yang Maha Esa. Ada banyak konflik yang terjadi sebagai dampak dari perbedaan suku, agama, ras dan antargolongan (SARA) sehingga mengganggu ketahanan bangsa. Konflik di tengah keberagaman tidak boleh dibiarkan sehingga perlu dilakukan berbagai upaya untuk mengatasinya. Pembahasan dalam artikel ini menggunakan metode kajian studi pustaka membahas fenomena yang terjadi berdasarkan kajian-kajian ilmiah yang telah ada dengan cara membaca, mencatat, dan mengolah bahan-bahan penelitian yang telah dipublikasi sebelumnya baik berupa buku, artikel jurnal, maupun teks lainnya. Adapun tujuan penulisan artikel ini untuk menjelaskan konsep pendidikan multikultural di tengah keberagaman masyarakat Indonesia serta proses pelaksanaan pembelajaran. Pendidikan multikultural merupakan satu metode pembelajaran yang bertujuan untuk menyatukan bangsa secara demokratis, dengan menekankan pada perspektif pluralitas masyarakat di berbagai bangsa, etnik, kelompok budaya yang berbeda. Proses pembelajaran pendidikan multikultural mengembangkan dan merencanakan suatu proses pembelajaran yang berafiliasi pada pendidikan berbasis multikultural dengan memasukkan materi pembelajaran yang relevan dengan unsur-unsur terkait. Guru sebagai garda depan dalam proses belajar mangajar mempunyai peran strategis dalam merencanakan, melaksanakan, dan mengembangkan pembelajaran yang berafiliasi Pendidikan berdasarkan multicultural dengan memberikan materi pelajaran yang berkaitan dengan Pendidikan multicultural. Tujuannya yaitu untuk membiasakan siswa didik menghargai perbedaan, berpikir kreatif dan bekerja sama dengan siswa-siswa lainnya dalam satu tim.
Analisis Kepuasan Pelayanan Keuangan Berdasarkan Kemampuan Kerja, Prosedur Pelayanan, dan Kualitas Pelayanan
Authors: Agustiani Nurul Huda , Permana Dhias Fajar Widya , Hanum Holy Latifah , Ismiyati Ismiyati , Sholikah Mar’atus 
Published: March 2024

Penelitian ini bertujuan untuk menganalisis pengaruh kemampuan kerja, prosedur pelayanan dan kualitas pelayanan terhadap kepuasan pelayanan pada Sub Bagian Keuangan Fakultas Ilmu Keolahragaan Universitas Negeri Semarang (UNNES). Penelitian kuantitatif digunakan dalam penelitian. Jumlah responden penelitian sebanyak 248 orang, dan diambil dengan teknik simple random sampling. Metode angket, wawancara, dan observasi merupakan metode dalam pengumpulan data penelitian ini. Hasil penelitian menemukan bahwa kemampuan kerja memiliki signifikansi sebesar 0.000, prosedur pelayanan memiliki signifikansi sebesar 0.001, dan kualitas pelayanan memiliki signifikansi sebesar 0,000. Dengan demikian, seluruh variabel independen yaitu kemampuan kerja, prosedur pelayanan, dan kualitas pelayanan memberikan pengaruh signifikan terhadap kepuasan pelayanan keuangan pada Sub Bagian Keuangan Fakultas Ilmu Keolahragaan UNNES. Kepuasan pelayanan akan menciptakan kepercayaan pelanggan, sehingga instansi sangat perlu memperhatikan komponen-kompenen yang mempengaruhinya seperti memperhatikan kemampuan kerja pegawai, prosedur pelayanan, dan kualitas pelayanan. Untuk itu, penelitian ini sangat berkontribusi bagi keberlanjutan pelayanan yang berkualitas dan memuaskan pelanggan di Fakultas Ilmu Keolahragaan UNNES.
Pengaruh Citra Merek, Harga, Iklan Televisi terhadap Keputusan Pembelian Mie Instan Sehat Lemonilo pada Mahasiswa Fakultas Ekonomi Universitas Islam “45”
Authors: Nurlela Farah , Pujihastuti Isti 
Published: March 2024

Penelitian ini untuk mengetahui pengaruh citra merek, harga, dan iklan televisi terhadap keputusan pembelian mie instan sehat Lemonilo pada mahasiswa fakultas Ekonomi Unisma. Metode penelitian yang digunakan penelitian ini adalah deskripsi kuantatif, sampel penelitian ini adalah 100 responden.. Hasil analisis menujukan bahwa nilai F hitung sebesar 25,345 dengan tingkat signifikan 0,000. Maka variabel citra merek, harga, dan ikan televisi secara simultan berpengaruh terhadap keputusa pembelian. Hasil uji secara parsial dari uji hipotesis bahwa variabel citra merek tidak signifikan terhadap keputusan pembelian uji t yaitu T hitung pada variabel citra merek X1= 0,690 dengan tingkat signifikan 0,492 lebih kecil dari 0,05. Variabel harga berpengaruh signifikan terhadap keputusan pembelian, nilai uji t yaitu T hitung pada variabel harga X2 = 3,706 dengan tingkat signifikan 0,000 lebih besar dari 0,05. Dan variabel iklan televisi berpengaruh signifikan terhadap keputusan pembelian, hal ini dibuktikan dari nilai uji t yaitu T hitung pada variabel iklan televisi X3 = 3,120 dengan tingkat signifikan 0,002 lebih besar dari 0,05. Dari hasil penelitian ini bahwa kontribusi variabel citra merek, harga, dan iklan televisi adalah sebesar 42,5 % sedangkan sisanya 57,5% dipengaruh oleh variabel atau faktor-faktor lain yang tidak diteliti dalam penelitian ini.
Penerapan Packaging dan Sales Promotion Pada Usaha Aksesoris Chattin Bers di Gudang Arang Ambon
Authors: Sutiksno Dian , Reasoa Wulan Ningsih , Nahuway Victor , Salhuteru Fentje 
Published: March 2024

The problem of MSMEs in Indonesia generally lies in capital and product marketing, so that many government programs have been implemented to improve the capabilities of MSMEs in management and technical aspects. For this reason, promotion and attractive packaging are needed to introduce accessory products that can be enjoyed by consumers in that place. In this study, the application of packaging and Sales Promotion is made that can help Chattin Bers accessories entrepreneurs to promote accessories using brochures and can sell them online through social media (Facebook, Instagram, and Shopee). The social media account used is a business account so that it can make it easier for the community so that it can make it easier for people to find and buy Chattin Bers accessories.
Ijarah Contracts From The Time Of Rasulullah To The Present Day
Authors: Abdurrahman Abdurrahman - , Muhajirin Muhajirin 
Published: March 2024

The Islamic banking industry in Indonesia continues to experience significant development. With this development, innovation in products and services in Islamic banking is very important to answer the needs in contemporary banking and financial transactions. One of the many products that have been applied and developed is ijarah. However, practitioners and scholars are still discussing different points of view regarding the legal basis of ijarah and its types. This research aims to review the development process of the ijarah principle and its variance from the early Islamic period to the present. This study is a qualitative research with a literature study approach and library research with descriptive analysis. This research concludes that, The concept of ijarah has existed since the time of the apostle of Allah, namely with the wage system given by the Rasulullah for the services received. For its application in the industry, there are 2 main products, namely Ijarah Muntahiya Bittamlik (IMBT) and Ijarah Maushufah Fi Al Dzimmah (IMDF).
Testing Positive for Covid-19, Signs and Symptoms, Treatment, and Covid-19-Related Anxiety: A Case of Factory Workers
Authors: Batı Serap , Burucu Rukiye 
Published: March 2024

Objective: This paper investigated the incidence of COVID-19 contraction, signs and symptoms, treatment, pandemic-related anxiety, and related factors in factory workers.
Methods: This was a descriptive study conducted in a factory operating in the textile industry. No sampling was performed. The sample consisted of 287 volunteers. Data were collected using a sociodemographic characteristics questionnaire and the Coronavirus Anxiety Scale Short Form.
Results: Less than half the participants tested positive for COVID-19 (41.1%). They were treated at home (68.6%) or in a hospital (19.5%). The most common symptoms were fatigue, joint pain, change in the sense of taste, and headache. The mean duration of home and hospital treatment was 7.00±0.00 and 12.49±6.14, respectively. Participants had a mean anxiety scale score of 7.65±3.71. Less than half the
participants (31%) had high COVID-19 anxiety levels. The incidence of COVID-19 infection and anxiety was higher in participants who were on medication for chronic illnesses. Age and BMI were correlated with hospitalization for COVID-19.
Conclusions: The incidence of COVID-19 infection is high among factory workers. Therefore, authorities should consider them a priority group for vaccination and provide them with training on COVID-19 risk factors and preventive measures.
PENERAPAN AKUNTANSI SYARIAH PADA BANK SYARIAH INDONESIA KANTOR CABANG PARE-PARE
Authors: Hasliah Hasliah , Adriani Adriani , Bakri Bakri 
Published: March 2024

Penelitian “Penerapan Akuntansi syariah pada Bank Syariah Indonesia Kantor Cabang Pare-Pare” bertujuan untuk mengetahui kesesuian penerapan akuntansi syariah pada bank tersebut dengan PSAK Syariah dan Undang-Undang Nomor 21 Tahun 2008 tentang Perbankan Syariah. Penelitian ini termasuk dalam penelitian deskriftif kualitatif, serta dalam metode pengumpulan data menggunakan teknik wawancara bebas namun terarah dan dokumentasi dokumen pendukung penelitian lainnya. Perbankan syariah menjadi salah satu alternatif masyarakat dan para pebisnis untuk melakukan transaksi dan bisnisnya. Selain itu peran bank lebih menyentuh kepada masyarakat luas karena terkait langsung dengan kegiatan ekonomi masyrakat. Salah satunya adalah Bank BSI Kantor Cabang Pare-Pare. Dalam menjalankan operasinya serta menawarkan berbagai produk dan layanannya Bank BSI Kantor Cabang Pare-Pare berdasarkan pada prinsip syariah yang berlandaskan pada Al Qur’an dan Hadist. Hasil penelitian yang dilakukan oleh penulis menunjukkan bahwa penerapan akuntansi syariah pada Bank BSI Kantor Cabang Pare-Pare telah sesuai PSAK Syariah serta Undang-Undang Nomor 21 Tahun 2008 serta berlandaskan pada Al Qur’an dan Hadist. Segala produk Bank Syariah Indonesia Kantor Cabang Pare Pare juga telah mendapatkan Fatwa Dewa Syariah Nasional Majelis Ulama Indonesia dan izin dari Otoritas Jasa Keuangan.
How to make full use of dental pulp stem cells: an optimized cell culture method based on explant technology
Authors: Wu You , Sun Jiangling , Wang Wang , Wang Yao , Friedrich Reinhard E. 
Published: March 2024

Introduction:Dental pulp stem cells from humans possess self-renewal and versatile differentiation abilities. These cells, known as DPSC, are promising for tissue engineering due to their outstanding biological characteristics and ease of access without significant donor site trauma. Existing methods for isolating DPSC mainly include enzyme digestion and explant techniques. Compared with the enzymatic digestion technique, the outgrowth method is less prone to cell damage and loss during the operation, which is essential for DPSC with fewer tissue sources.Methods:In order to maximize the amount of stem cells harvested while reducing the cost of DPSC culture, the feasibility of the optimized explant technique was evaluated in this experiment. Cell morphology, minimum cell emergence time, the total amount of cells harvested, cell survival, and proliferative and differentiation capacity of DPSC obtained with different numbers of explant attachments (A1-A5) were evaluated.Results:There was a reduction in the survival rate of the cells in groups A2-A5, and the amount of harvested DPSC decreased in A3-A5 groups, but the DPSC harvested in groups A1-A4 had similar proliferative and differentiation abilities. However, starting from group A5, the survival rate, proliferation and differentiation ability of DPSC decreased significantly, and the adipogenic trend of the cells became more apparent, indicating that the cells had begun to enter the senescence state.Discussion:The results of our study demonstrated that the DPSC obtained by the optimized explant method up to 4 times had reliable biological properties and is available for tissue engineering.
Does erectile dysfunction predict cardiovascular risk? A cross-sectional study of clinical characteristics in patients with erectile dysfunction combined with coronary heart disease
Authors: Li Luyu , Zhang Yongtao , Ma Miaomiao , Liu Feng , Shang Yihan , Yuan Quan , Li Xiao , Ju Baojun 
Published: March 2024

BackgroundErectile Dysfunction (ED) is a common sexual dysfunction in men who are unable to consistently obtain and maintain sufficient penile erection to accomplish a satisfactory sexual life. ED is currently considered to be a predictor of cardiovascular disease (CVD), but few studies have observed the association between ED and clinical features of coronary heart disease (CHD). An investigation of the association between ED and clinical characteristics of CHD was carried out using a cross-sectional study design.MethodsThis cross-sectional single-center study was conducted in the Department of Cardiology and included 248 patients. Associations between patients' general information, underlying disease information, coronary heart disease information, and ED severity were statistically and analytically analyzed using SPSS 26.0 software. Patients with comparable clinical characteristics were grouped together using K-means clustering. Finally, ordered logistic regression analysis was performed for general and underlying disease information.ResultsIn the comparison of general data, age, education, and weekly exercise were associated with the distribution of ED severity. In the comparison of underlying disease information, the number of underlying diseases, hypertension, diabetes, hyperlipidemia, anxiety state, and depressive state were associated with the distribution of ED severity. In the comparison of CHD information, the degree of ED severity was associated with CHD subtypes, lesion sites, number of stenoses, degree of stenosis, and interventional interventions. The time from ED to CHD onset was associated with the subtypes of CHD and the number of stenoses. We clustered the main characteristics of low-risk and high-risk patients and ordered logistic regression analysis found that BMI, smoking, alcoholism, number of underlying diseases, diabetes, anxiety state, and depression state were all risk factors for CHD severity (P &lt; 0.05); the higher the value of the above factors, the more severe the degree of CHD. Age was a protective factor for CHD severity; the younger the patient, the lower the likelihood of myocardial infarction.ConclusionED severity and the time from ED to CHD onset may be predictive of coronary heart disease severity. Reducing smoking and alcohol consumption, maintaining a healthy body weight, and regular physical activity are important in preventing CVD in ED patients.
Association between Metabolic Score for Visceral Fat and the risk of hypertension in different ethnic groups: a prospective cohort study in Southwest China
Authors: Zhang Fuyan , Wang Yiying , Zhou Jie , Yu Lisha , Wang Ziyun , Liu Tao , Yu Yangwen 
Published: March 2024

ObjectiveVisceral adipose tissue assessment holds significant importance in hypertension prevention. This study aimed to explore the association between the Metabolic Score for Visceral Fat (METS-VF), a new indicator based on laboratory and anthropometry measures, and hypertension risk and to further investigate the association between the METS-VF and the risk of hypertension in different ethnic groups.MethodsIn this study, a total of 9,280 people from 48 townships in 12 districts (counties) of Guizhou Province were selected for the survey using a multistage cluster random sampling method, and 5,127 cases were finally included in the analysis after excluding those with missing relevant data, losing visits, dying at follow-up, those who suffered from hypertension at baseline, and those whose information on the outcome of hypertension was not clear. Cox proportional hazard models were used to estimate hazard ratios (HRs) and 95% confidence intervals (95% CIs) between METS-VF and incident hypertension, and an accelerated failure time (AFT) model was applied to analyze the association between METS-VF and the onset time of hypertension.ResultsThe total person-years (PYs) of the 5,127 subjects were 36,188.52 years, and the median follow-up time was 6.64 years. During follow-up, 1,127 patients were newly diagnosed with hypertension, and the incidence density was 31.14/1,000 PYs. After adjusting for multivariables, compared with the METS-VF first (Q1), the third (Q3) and fourth (Q4) groups of the METS-VF increased by 29.9% and 61.5%, respectively (HR = 1.299 [1.061, 1.590] and 1.615 [1.280, 2.036]). The risk of hypertension increased with higher METS-VF values (HR = 1.323 [1.167, 1.500], ptrend &lt; 0.001). In the Han Chinese population, Q2 and Q3 increased the risk of hypertension (HR = 1.459 [1.111, 1.917], 1.999 [1.417, 2.718]), and the onset of hypertension was advanced by 0.653 (β = −0.653 (−0.930, −0.375]) years for per 1 unit increase in METS-VF. However, these associations were not found in ethnic minorities.ConclusionMETS-VF was significantly positively associated with the risk of hypertension, and the association was different among ethnic groups.
Association between non-scarring alopecia and hypothyroidism: a bidirectional two-sample Mendelian randomization study
Authors: Yang Jiankang , Zhu Zhenlai , Zhang Chen , Guo Yanyang , Wang Gang , Fu Meng 
Published: March 2024

BackgroundNon-scarring alopecia is typically represented by two main types: alopecia areata (AA) and androgenetic alopecia (AGA). While previous observational studies have indicated a link between non-scarring alopecia and hypothyroidism, the precise causal relationship remains uncertain. To determine the potential links between non-scarring alopecia and hypothyroidism, we conducted a bidirectional two-sample Mendelian randomization (MR) analysis.MethodsWe used independent genetic instruments from the FinnGen consortium for AA (682 cases, 361,140 controls) and AGA (195 cases, 201,019 controls) to investigate the association with hypothyroidism in the UK Biobank study (22,687 cases, 440,246 controls). The primary analysis was performed using the inverse variance-weighted method. Complementary approaches were employed to evaluate the pleiotropy and heterogeneity.ResultsGenetically predicted AA exhibited a positive causal effect on hypothyroidism (odds ratio [OR], 1.0017; 95% confidence interval [CI], 1.0004-1.0029; P = 0.0101). Additionally, hypothyroidism was found to be strongly correlated with an increase in the risk of AA (OR, 45.6839; 95% CI, 1.8446-1131.4271, P = 0.0196). However, no causal relationship was demonstrated between AGA and hypothyroidism. A sensitivity analysis validated the integrity of these causal relationships.ConclusionThis MR study supports a bidirectional causal link between AA and hypothyroidism. Nevertheless, additional research is needed to gain a more thorough comprehension of the causal relationship between non-scarring alopecia and hypothyroidism.
A division-of-labor mode contributes to the cardioprotective potential of mesenchymal stem/stromal cells in heart failure post myocardial infarction
Authors: Wang Xicheng , Yang Chao , Ma Xiaoxue , Li Xiuhua , Qi Yiyao , Bai Zhihui , Xu Ying , Ma Keming , Luo Yi , Song Jiyang , Jia Wenwen , He Zhiying , Liu Zhongmin 
Published: March 2024

BackgroundTreatment of heart failure post myocardial infarction (post-MI HF) with mesenchymal stem/stromal cells (MSCs) holds great promise. Nevertheless, 2-dimensional (2D) GMP-grade MSCs from different labs and donor sources have different therapeutic efficacy and still in a low yield. Therefore, it is crucial to increase the production and find novel ways to assess the therapeutic efficacy of MSCs.Materials and methodshUC-MSCs were cultured in 3-dimensional (3D) expansion system for obtaining enough cells for clinical use, named as 3D MSCs. A post-MI HF mouse model was employed to conduct in vivo and in vitro experiments. Single-cell and bulk RNA-seq analyses were performed on 3D MSCs. A total of 125 combination algorithms were leveraged to screen for core ligand genes. Shinyapp and shinycell workflows were used for deploying web-server.Result3D GMP-grade MSCs can significantly and stably reduce the extent of post-MI HF. To understand the stable potential cardioprotective mechanism, scRNA-seq revealed the heterogeneity and division-of-labor mode of 3D MSCs at the cellular level. Specifically, scissor phenotypic analysis identified a reported wound-healing CD142+ MSCs subpopulation that is also associated with cardiac protection ability and CD142- MSCs that is in proliferative state, contributing to the cardioprotective function and self-renewal, respectively. Differential expression analysis was conducted on CD142+ MSCs and CD142- MSCs and the differentially expressed ligand-related model was achieved by employing 125 combination algorithms. The present study developed a machine learning predictive model based on 13 ligands. Further analysis using CellChat demonstrated that CD142+ MSCs have a stronger secretion capacity compared to CD142- MSCs and Flow cytometry sorting of the CD142+ MSCs and qRT-PCR validation confirmed the significant upregulation of these 13 ligand factors in CD142+ MSCs.ConclusionClinical GMP-grade 3D MSCs could serve as a stable cardioprotective cell product. Using scissor analysis on scRNA-seq data, we have clarified the potential functional and proliferative subpopulation, which cooperatively contributed to self-renewal and functional maintenance for 3D MSCs, named as “division of labor” mode of MSCs. Moreover, a ligand model was robustly developed for predicting the secretory efficacy of MSCs. A user-friendly web-server and a predictive model were constructed and available (https://wangxc.shinyapps.io/3D_MSCs/).
Comprehensive investigation into the influence of glycosylation on head and neck squamous cell carcinoma and development of a prognostic model for risk assessment and anticipating immunotherapy
Authors: Ma Heng , Xiong Ludan , Zhao Bohui , Hahan Zhuledesi , Wei Minghui , Shi Hengmei , Yang Susu , Ren Qianhe 
Published: March 2024

BackgroundIt has been well established that glycosylation plays a pivotal role in initiation, progression, and therapy resistance of several cancers. However, the correlations between glycosylation and head and neck squamous cell carcinoma (HNSCC) have not been elucidated in detail.MethodsThe paramount genes governing glycosylation were discerned via the utilization of the Protein-Protein Interaction (PPI) network and correlation analysis, coupled with single-cell RNA sequencing (scRNA-seq) analysis. To construct risk models exhibiting heightened predictive efficacy, cox- and lasso-regression methodologies were employed, and the veracity of these models was substantiated across both internal and external datasets. Subsequently, an exploration into the distinctions within the tumor microenvironment (TME), immunotherapy responses, and enriched pathways among disparate risk cohorts ensued. Ultimately, cell experiments were conducted to validate the consequential impact of SMS in Head and Neck Squamous Cell Carcinoma (HNSCC).ResultsA total of 184 genes orchestrating glycosylation were delineated for subsequent scrutiny. Employing cox- and lasso-regression methodologies, we fashioned a 3-gene signature, proficient in prognosticating the outcomes for patients afflicted with HNSCC. Noteworthy observations encompassed distinctions in the Tumor Microenvironment (TME), levels of immune cell infiltration, and the presence of immune checkpoint markers among divergent risk cohorts, holding potentially consequential implications for the clinical management of HNSCC patients.ConclusionThe prognosis of HNSCC can be proficiently anticipated through risk signatures based on Glycosylation-related genes (GRGs). A thorough delineation of the GRGs signature in HNSCC holds the potential to facilitate the interpretation of HNSCC’s responsiveness to immunotherapy and provide innovative strategies for cancer treatment.