bluuebunny/crossref_metadata_2025_split huggingface dataset:
Interventions during the copycat suicide crisis among Thai students: A follow-up study
Authors: Jatchavala Chonnakarn 
Published: March 2024

ABSTRACT

Objective:
To survey patterns of psychotropic drug prescription, psychotherapy, and their associations with suicidal risk among Thai university students during the copycat suicide crisis and the subsequent 6 month follow-up.

Methods:
This time-series study had two phases; each lasted for 4 weeks in March and September 2019. All university students who accessed psychiatric services at the outpatient unit of our university hospital were enrolled automatically. Patient data, such as personal information, diagnosis, drug prescription, psychosocial intervention, and suicide screening score (Thai-version 8Q), were collected from the hospital’s database. Descriptive data analysis via the Chi-square test and logistic regressions was conducted using the R-program (the R foundation,Vienna, Austria).

Results:
During the height of the copycat suicide crisis in Thailand and the following 6 months, antidepressants were prescribed most often (73.8% and 78.6%) and most of the students received only psychoeducation (67.5% and 61.9%). Psychoeducation was found to associate with a decreased suicidal risk during the 6 month follow-up (P = 0.019). During the crisis, depressive disorders, bipolar disorders, and mood stabilizer prescriptions were significantly associated with an increased suicidal risk (P = 0.002 and 0.01, respectively). Only antipsychotics prescription showed a statistically significant association at 6 months following the crisis (P = 0.031).

Conclusion:
Predominantly, Thai university student psychiatric outpatients were prescribed antidepressants and received psychoeducation during the copycat suicide crisis and 6 months after. Mood disorders and mood stabilizer prescription were significantly associated with an increased suicidal risk during the crisis, whereas antipsychotics prescription was associated with the same at 6 months later.
Clinical profile of coronavirus disease 2019 among vaccinated health-care workers in a tertiary care teaching institute from Uttar Pradesh
Authors: Shukla Surabhi , Singh Peetam 
Published: March 2024

ABSTRACT

Background:
India’s national coronavirus disease 2019 (COVID-19) vaccination program started in January 2021 and prioritized health-care workers (HCWs). This study was conducted to assess vaccine effectiveness among COVID-19-vaccinated HCWs and symptomatology in reverse transcription-polymerase chain reaction (RT-PCR) confirmed COVID-19 among HCWs.

Materials and Methods:
This cross-sectional study was conducted in a tertiary care medical teaching institute from Uttar Pradesh during the second wave of COVID-19 (from February 2021 to June 2021). All RT-PCR-confirmed COVID-19 HCWs were divided into various groups depending on their vaccination status. The data regarding demographic profile along with vaccination status, the gap between COVID-19 positivity and vaccination, symptoms, hospitalization, time to recovery, and previous history of COVID-19 were recorded.

Results:
A total of 1685 HCWs vaccinated with the Covishield vaccine from January to March 2021 were inquired. Out of 1685 HCWs, 82 (4.8%) were tested positive by RT-PCR after vaccination. Of 82 positive HCWs, 84% experienced mild symptoms, 12.2% experienced moderate symptoms, and 3.7% experienced severe manifestations leading to hospitalization. Among these positive HCWs, 25.6% recovered within 7 days, 35.3% recovered in 7–10 days, 15.8% recovered in 11–14 days, and 23.1% recovered after 2 weeks from the 1st day of experiencing symptoms. Among nonvaccinated patients, 878 (5.3%) required hospitalization.

Conclusion:
COVID-19 vaccination by Covishield may not fully prevent from infection by severe acute respiratory syndrome coronavirus 2 or its different variants. Few postvaccination cases may present with severe symptoms and require hospitalization.
Demographic and clinical profile of oral lichen planus: A retrospective study
Authors: Nosratzehi Tahereh , Kadeh Hamideh , Mohsenzadeh Hedyeh 
Published: March 2024

ABSTRACT

Background:
Oral lichen planus (OLP) is a prevalent chronic mucous skin disorder which embraces oral mucosa; the etiology of this disease is not known; however, the immunological system plays an important role.

Aims and Objectives:
This study aims to determine the demographic and clinical information of patients with OLP referred to the Dentistry School of Zahedan University.

Materials and Methods:
To determine the demographic and clinical information of patients with OLP referred to the Dentistry School of Zahedan University, a cross-sectional study has been proposed. All the information forms of patients with OLP including personal information such as age, gender, lesion location, clinical form of lesion, the time duration of lesions, the symptoms, and diagnosis time were reviewed. Then, the information was extracted and registered in a list for this purpose.

Results:
The results of the study suggested that 32 (67%) patients were female, buccal was the most involved location, and 91.9% of patients suffered from this disorder for more than 3 months. The nonerosive lesions formed the most part of the clinical form (40%). Furthermore, results suggested that 50% of patients suffered from irritation in the lesion location.

Conclusion:
With regard to malignancy of lichen and the WHO considered it as a premalignant lesion and three of our patients had squamous cell carcinoma, following up the patients with oral lichen was accentuated.
A comparative study on sequential single-agent chemotherapy followed by radiation versus single-agent chemotherapy alone in elderly patients of metastatic non-small cell lung cancer
Authors: Devi Adhikarimayum Ambika , Devi Laishram Purnima , Singh Yengkhom Indibor , Nirpendra Thangjam , Kamei Ram , Ramalingam Manirathinam 
Published: March 2024

Background:
Stage IV non-small cell lung cancer (NSCLC) in elderly patients typically has a poor prognosis and addition of aggressive local therapy to the systemic therapy could provide encouraging outcomes with prolonged survival in certain patients with stage IV NSCLC.

Objectives:
The aim of this study is to compare the treatment response and progression-free survival (PFS) between single-agent chemotherapy (CT) followed by external-beam radiotherapy versus single-agent CT alone in elderly patients with metastatic NSCLC.

Materials and Methods:
In a randomized prospective study, after taking Ethical committees approval, 40 patients aged from 60 to 82 years were enrolled and divided into two equal groups: Arm A and Arm B. Both the arms received Gemcitabine 1 g/m2/dose as 30 min intravenous infusion on D1, D8, and D15 of 28-day cycle or D1 and D8 of a 21-day cycle for a total of 3–4 cycles, whereas Arm A received radiation 45–55 Gy @ 180 cgy/fraction after CT. Treatment response and PFS against time were analyzed using Friedman's test and Kaplan − Meier method. P < 0.05 was considered statistically significant.

Results:
The demographic profiles of the patients were comparable between the two groups. Most patients have Stage IV M1b disease and squamous cell carcinoma subtype and bone metastasis. There were marked symptomatic improvements in both the arms. The overall treatment response was 70.0% in Arm A and 50.0% in Arm B with median follow-up was 8 months. Median PFS and overall survival were 5 months and 8 months for arm A, respectively whereas it was 4 months and 7 months for Arm B (P = 0.03).

Conclusion:
In this study, it was found that sequential single agent CT followed by radiation has shown survival advantage in certain patients with Stage IV NSCLC.
PENGARUH PEMBERIAN KOLKISIN DENGAN DROP METHOD TERHADAP PERTUMBUHAN BIBIT JABON (Anthocephalus cadamba)
Authors: Anwar Arniani , Evelin Anggelina Tanur  , Worabai Descarlo , Laswi Irmayanti  , Reyna Ashari  , Ahmad Baiquni Rangkuti  
Published: March 2024

Jabon merupakan salah satu jenis tanaman yang sedang populer dibudidayakan oleh masyarakat dan industri pemasok kayu. Kolkisin merupakan senyawa alkaloid yang memiliki kemampuan membentuk tanaman yang poliploid. Sebagai upaya untuk meningkatkan produktifitas jabon maka diperlukan adanya terobosan baru. Salah satunya dengan pemberian colchicine pada bibit jabon. Perlakuan kolkisin pada penelitian ini sebagai upaya untuk meningkatkan produktifitas jabon maka diperlukan adanya terobosan baru. Salah satunya dengan pemberian kolkisin pada bibit jabon. Jumlah perlakuan yang digunakan dalam penelitian ini adalah 5 perlakuan dengan 45 kali jumlah ulangan pada setiap perlakuannya. Untuk 4 perlakuan diberi kosentrasi colchicine dengan kosentrasi yang berbeda-beda (0,500 mg/l, 1,000 mg/l, 1,500 mg/l, dan 2,000 mg/l) dan 1 perlakuan berfungsi sebagai kontrol di mana tanaman kontrol ini tidak diberi colchicine. Rancangan yang digunakan adalah rancangan acak lengkap (RAL). Pemberian colchicine dalam penelitian ini memberikan pengaruh yang nyata pada pertumbuhan bibit jabon. Pengaruh pertumbuhan tersebut terjadi pada semua variabel yang diamati, baik pertambahan jumlah daun, pertumbuhan tinggi tunas maupun diameter. Empat konsentrasi colchicine yang diberikan, perlakuan E dengan konsentrasi 2,000 mg/l merupakan konsentrasi yang memberikan pengaruh pertumbuhan terbaik terhadap bibit jabon.

Kata Kunci: Jabon, kolkisin, poliploid, RAL, konsentrasi
ANALISIS TINGKAT KESEHATAN HUTAN REBOISASI DI BUKIT GOLO LUSANG KAWASAN TAMAN WISATA ALAM (TWA) RUTENG
Authors: Edon Servasius Gratia , Seran Wilhelmina , Sinaga Pamona Silvia 
Published: March 2024

Menjaga hutan dapat dilakukan dengan menilai tingkat kesehatan hutannya. Penilaian dapat dilakukan dengan menggunakan metode Forest Health Monitoring. Penelitian dilakukan untuk mengetahui kondisi kesehatan hutan reboisasi Golo Lusang mengamati paramater dalam setiap indikator metode FHM seperti indikator vitalitas dengan parameter kerusakan pohon, produktivitas dengan parameter diameter pohon, biodiversitas dengan parameter keanekaragaman dan kekayaan, dan kualitas tapak dengan parameter keasaman tanah. Penelitian dilakukan pada tanggal 28 Desember 2022–28 Januari 2023 pada 2 klaster plot pengamatan. Hasil penelitian menunjukkan kerusakan tingkat klaster plot sebesar 0,5875 klaster plot 1, dan sebesar 0,9975 klaster plot 2 yang berarti tingkat kesehatan hutan reboisasi Golo Lusang dinilai dari indikator vitalitas parameter kerusakan pohon berkategori sehat. Hasil pengukuran produktivitas yaitu 0,021 m2 rata-rata LBDS klaster plot 1 dan 0,016 m2 rata-rata LBDS klaster plot 2. Sedangkan nilai volume sebesar 0,17 m3 rata-rata volume klaster plot 1 dan 0,14 m3 rata-rata volume klaster plot 2. Penilaian biodiversitas dengan parameter kekayaan jenis menunjukkan angka 1,0325 klaster plot 1 (rendah) dan 2,9425 klaster plot 2 (sedang) serta parameter keanekaragaman jenis menunjukkan angka 1,0475 klaster plot 1 (sedang) dan 2,1925 klaster plot 2 (sedang). Penilaian kualitas tapak klaster plot 1 sebesar 6,67 dan klaster plot 2 sebesar 6,83 menunjukkan kualitas tapak pada area reboisasi Golo Lusang berkategori baik.
The Relationship Between Type and Position of Fungal Infection with Age and Gender
Authors: Fanosh Mohammed Hessiun , Eljamay Salwa Muftah , Elzer Ashraf Saad , Alkirbal Hamdi Abdulbasit 
Published: March 2024

Dermatophytosis is a superficial fungal infection caused by filamentous fungi that attack the keratinized tissue. Aimed to: the find out relationship between type and position of fungal infection with age and gender. Material and Methods: This cross-sectional survey study was carried out at the dermatology department, from August 2021 to July 2023. Results: The ages most affected by fungi were between 17 and 32 years old at 60%, followed by the oldest age over 35 years old. The females were the most infected with fungi, 93 out of 155. As for the type of infection, yeast was the highest, especially in 60 women. hyphae 28 and spores 8 where males were less infectious, the relationship between gender and fungal position, because p-value < 0.05, As for the type of fungus and its existence, it has nothing to do with gender because p-value > 0.05, it has nothing to do with gender because p-value > 0.05, and the relationship between age and presence of fungal infection, because p-value < 0.05, the type of fungus and position of fungal infection, it has nothing to do with age because p-value > 0.05. Conclusion: females are more likely to be infected with fungi, whether they are by infection type or location, and the most infected ages are between 17 and 32 years old. The study also showed that the place of infection in nails was found in males and there was no infection in females.
Effectiveness of Mediation and Arbitration as Alternative Dispute Resolution Methods in Mexico
Authors: Pablo Juan 
Published: March 2024

Purpose: To aim of the study was to analyze effectiveness of mediation and arbitration as alternative dispute resolution methods
Methodology: This study adopted a desk methodology. A desk study research design is commonly known as secondary data collection. This is basically collecting data from existing resources preferably because of its low cost advantage as compared to a field research. Our current study looked into already published studies and reports as the data was easily accessed through online journals and libraries.
Findings: Mediation and arbitration offer efficient, cost-effective alternatives to litigation. Mediation involves facilitated negotiation sessions with a neutral mediator, fostering open communication and tailored solutions. Arbitration entails submitting disputes to a neutral arbitrator for a binding decision. Both methods ensure confidentiality, expertise, and enforceability, making them highly effective in resolving disputes outside of court.
Unique Contribution to Theory, Practice and Policy: Theory of social exchange, justice theory & game theory may be used to anchor future studies on effectiveness of mediation and arbitration as alternative dispute resolution methods. Practitioners in the field of alternative dispute resolution should prioritize enhancing their skills and competencies to effectively facilitate mediation and arbitration processes. Policymakers should prioritize the promotion of mediation and arbitration as viable alternatives to traditional litigation within legal frameworks and regulatory environments.
Evaluating the Physiochemical and Nutritional Attributes of Dates (Phoenix Dactylifera) Based Cupcakes
Authors: Hassan Ahmed , Ashfaq Javeria , Mudassar Muhammad , Sadiq Dr yasir , Naz Tabana , Saeed Sumaira , Raza Muhammad Qasim 
Published: March 2024

Purpose: The proximate analysis aimed to determine nutritional profile of the cupcakes including moisture, crude fat, crude fiber, crude protein, ash, pH and acidity values, while the physicochemical analysis was performed to study total phenolic and total flavonoids contents. The organoleptic attributes if date cupcakes were studied by using nine points hedonic scale for texture, color, volume, flavor, aroma and hardness.
Materials and Methods: Exploratory research design was opted for qualitative and quantitative study of five treatments of date cupcakes aimed to address their dietary significance with respect to shelf life status, nutritional content as well as phytochemical and physicochemical analysis. Dates were purchased from intensive farmers from Multan division, Dera Ismail khan and from local markets. The dates were sorted, graded and washed with chlorinated water to remove field waste. The substitute fruit sample was conveyed to Food Science & Technology lab of Minhaj University Lahore under controlled conditions for further studies. The dates enriched cupcakes with different percentages of date pulp (5%, 10%, 15%, 20%, and 25%) along with control (without date pulp) were subjected for proximate, phytochemical and physicochemical analysis.
Findings: The calculated resulted were compared with control and it was concluded that the overall acceptability and stability of cupcakes with 20% date pulp was greater than other percentages.
Implications to Theory, Practice and Policy: Phoenix dactylifera is among the oldest plants cultivated by men. The nutritional, industrial, medical and environmental importance of this plant is globally acknowledged. Current studies focus on nutritional significance of Phoenix dactylifera when used as a natural additive in cupcakes.
The Effects of the Coronavirus Pandemic on the Indicators of the End Tuberculosis Strategy: A Literature Review
Authors: Matakanye Hulisani 
Published: March 2024

Coronavirus disease 2019 (COVID-19) had severely taken a toll on the health system in all nations from the wealthiest to the poorest countries. The disruption to the health system was not only due to the direct effects of the COVID-19 pandemic but also the pressure it caused to stretch the health systems beyond their capability indirectly. The purpose of this review was to explore the effects of the COVID-19 pandemic on the indicators of the end tuberculosis strategy. Methods: Articles were searched from scientific search engines such as CINAHL Plus (EBSCO), PubMed, Google Scholar, Medline, ProQuest, APA Psych, INFO as well as manual searches through Google and Google Scholar search engines. Both quantitative and qualitative studies that showed the impact or effects of the COVID-19 pandemic on TB diagnosis, TB patient management, treatment initiation, treatment adherence, patients’ loss to follow up were included. A total of 375 articles were screened, and 12 full-text articles were ultimately included in the review. Findings: The extracted impact were synthesized thematically into three indicators of the end TB strategy: impact on TB incidence rate; impact on TB deaths; Impact on catastrophic costs due to TB. Conclusion: The COVID-19 pandemic has affected the three indicators of the end TB strategy and has significantly reversed the global TB progress in the fight to end TB epidemic. This has increased the risk of TB incidence, deaths, and the severity of economic impact on TB-affected households. Therefore, there is a need for countries to take step forward and develop intervention strategies that will help them to resolve the damage caused by the pandemic on the achieve the targets to end TB. This study could improve strategies implementation regarding the management of TB disease.
Retrospective Case Analysis on the Effectiveness of Boerhavia Diffusa Mother Tincture in the Management of Essential Hypertension
Authors: Sabarirajan S , Aayesha A 
Published: March 2024

Background: Hypertension is a prevalent medical condition with significant health implications. This retrospective case record analysis aimed to investigate the efficacy of Boerhaavia diffusa mother tincture in managing hypertension. The study utilized data from diverse healthcare settings affiliated with Sivaraj Homoeopathic Medical College and Research Institute, Salem. Methods: A total of 30 cases meeting the inclusion criteria, comprising both sexes aged between 30 to 75 years, diagnosed with hypertension based on clinical parameters (systolic BP >140 mmHg, diastolic BP >90 mmHg), and presenting common symptoms, were included. Exclusion criteria encompassed cases of secondary hypertension and those with incomplete follow-ups. The efficacy of Boerhaavia diffusa mother tincture was assessed by changes in blood pressure recorded during the treatment period. The study adhered to ethical guidelines, and all patients received Boerhaavia diffusa mother tincture as part of their therapeutic regimen. Results and Discussion: Among the 30 cases analyzed, 6 patients exhibited marked improvement, 10 demonstrated moderate improvement, and 10 showed mild improvement, while 4 cases showed no improvement. Notably, the majority of patients experienced marked symptomatic relief. Despite the positive trend observed in the outcomes, the study has limitations, including a small sample size and the absence of a control group. The lack of detailed information on dosage and treatment duration further restricts the generalizability of the findings. The retrospective nature of the analysis introduces potential biases, and confounding factors such as lifestyle changes were not systematically addressed. Conclusion: This retrospective case record analysis suggests a potential beneficial effect of Boerhaavia diffusa mother tincture in managing hypertension. The majority of patients experienced symptomatic relief, although caution is warranted due to study limitations. Future research, including well-designed randomized controlled trials with larger sample sizes, is needed to establish the efficacy and safety of Boerhaavia diffusa mother tincture in hypertensive patients.
The Utility of Upcoming Fish Models in Homoeopathy: A Scoping Review
Authors: Khachane Monica Nandkumar , Mukherjee Anupam , Arulmozhi S , Ghate Varsha Umesh 
Published: March 2024

Background: Fish is the earliest, most prolific, and most diversified class of vertebrates with around 34,000 species. Various species of fish have been used as research models all around the world to provide insights into intricate human genetics, anatomical and physiological systems, and the pathophysiology of human illnesses. Aim: This study aimed to highlight experimental studies of fish models in Homoeopathy using a variety of evaluation parameters along with validated analytical tools for traceable evidence. Methods: The information was gathered for preclinical research studying the impact of Homoeopathic formulations on disorders in a variety of fish, from a number of databases such as Scopus, Science Direct, Web of Science, PubMed, Research Gate, and Google Scholar. Result: There were 30 publications in all that were evaluated, and of them, 25 met the inclusion criteria and were included in the scoping review. Conclusion: The use of fish models in Homoeopathic research can be considered to be valuable as it gives a versatile approach that can significantly contribute to our understanding of biology, disease, and environmental science. Subsequently, the fish models enhance the ability of researchers to make advanced discoveries in various fields of study.
Homoeopathy in Covid 19 Sequelae: A Case of Telogen Effluvium
Authors: Singh Shweta 
Published: March 2024

Hair loss is one of the most prevalent complaints in patients shortly after being infected with Covid-19, reported more commonly in women. The most likely cause could be either the pathogenetic aspects or psychiatric complications of Covid-19, which can lead to the appearance or aggravation of hair loss. Homoeopathy has a vital role to play in such areas; where no specific therapeutic intervention is available in modern medicine especially when the disease is stress induced. Since Homoeopathy is the only healing science that takes care of the patient as a whole; the root cause, the physical and mental state of the patient along with the disease symptoms which individualizes the patient from one another are the basis of accurate and effective homoeopathic prescription. Following the cardinal principles, significant improvement and recovery was seen in such cases with homoeopathic remedies.
Role of Drug Remedies in Attention Deficit Hyperactivity Disorder (ADHD): A Case Series
Authors: Goyal Aditi , Singh Muktinder 
Published: March 2024

Introduction: ADHD is the most common neurobe havioral disorder in children which comprises of 3 types: inattentive/hyperactive-impulsive/combined type. There are varied drugs in homoeopathy belong ing to narcotic groups which seems to be effective in these type of cases. These groups have various alka loids whose main sphere of action is on CNS or PNS as stimulant, depressor or hypnotic. Case summary: Here, 3 cases are presented with different types of ADHD as diagnosed by Vanderbilt Diagnostic Scale. In all these cases homoeopathic drug remedies were prescribed on the basis of totality of symptoms. Marked improvement in all the cases substantiate the effectiveness of homoeopathy especially drug remedies in these type of behavioural problems when given constitutionally.