bluuebunny/crossref_metadata_2025_split huggingface dataset:
Synthesis and Biological Evaluation of New Pyrimidine Derivatives.
Authors: Fathalla O. A. , Radwan H. H. , Awad S. M. , Mohamed M. S. 
Published: August 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Synthesis of Non‐Nucleosides: 7‐ and 1,3‐Substituents of New Pyrrolo[2,3‐d]pyrimidin‐4‐ones on Antiviral Activity.
Authors: Hilmy Khalid Mohammed Hassan 
Published: August 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Design and Synthesis of 7H‐Pyrrolo[2,3‐d]pyrimidines as Focal Adhesion Kinase Inhibitors. Part 2.
Authors: He Yun , et al. et al. 
Published: August 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Stereoselective Synthesis of 2‐Hydroxymorpholines and Aminodiols via a Three‐Component Boro‐Mannich Reaction.
Authors: Berree Fabienne , Debache AbdelMajid , Marsac Yohann , Collet Beatrice , Girard‐Le Bleiz Pascale , Carboni Bertrand 
Published: August 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
A General and Efficient Synthesis of 3,6‐Diazabicyclo[3.2.1.]octanes.
Authors: Singh Rakesh K. , Jain Sanjay , Sinha Neelima , Mehta Anita , Naqvi Fehmida , Anand Nitya 
Published: August 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
A One‐Pot Synthesis and Self‐Assembled Superstructure of Organic Salts of a 1,5‐Benzodiazepine Derivative.
Authors: Thakuria Harjyoti , Pramanik Avijit , Borah Ballav Moni , Das Gopal 
Published: August 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Direct Boronation of Allyl Alcohols with Diboronic Acid Using Palladium Pincer‐Complex Catalysis. A Remarkably Facile Allylic Displacement of the Hydroxy Group under Mild Reaction Conditions.
Authors: Olsson Vilhelm J. , Sebelius Sara , Selander Nicklas , Szabo Kalman J. 
Published: August 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Silylformylation — Fluoride‐Assisted Aryl Migration of Acetylenic Derivatives in a Versatile Approach to the Synthesis of Polyfunctionalized Compounds.
Authors: Aronica Laura Antonella , Raffa Patrizio , Valentini Giulia , Caporusso Anna Maria , Salvadori Piero 
Published: August 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
[3,3]‐Rearrangements of Phosphonium Ylides.
Authors: Ferguson Marcelle L. , Senecal Todd D. , Groendyke Todd M. , Mapp Anna K. 
Published: August 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Orally Active Thrombin Inhibitors. Part 1. Optimization of the P1‐Moiety.
Authors: Mack Helmut , Baucke Dorit , Hornberger Wilfried , Lange Udo E. W. , Seitz Werner , Hoeffken H. Wolfgang 
Published: August 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Total Synthesis of Two Novel 5,6,7,8‐Tetrahydroindolizine Alkaloids, Polygonatines A (Ia) and B (Ib).
Authors: Dinsmore Andrew , Mandy Karen , Michael Joseph P. 
Published: August 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Total Synthesis of Enantiopure (+)‐γ‐Lycorane Using Highly Efficient Pd‐Catalyzed Asymmetric Allylic Alkylation.
Authors: Chapsal Bruno D. , Ojima Iwao 
Published: August 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Synthesis and Biological Evaluation of B‐Ring Modified Colchicine and Isocolchicine Analogues.
Authors: Cifuentes Michael , Schilling Brett , Ravindra Rudravajhala , Winter Jacquelyn , Janik Mark E. 
Published: August 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Dimerization of (+)‐Myrmicarin 215B. A Potential Biomimetic Approach to Complex Myrmicarin Alkaloids.
Authors: Ondrus Alison E. , Movassaghi Mohammad 
Published: August 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Synthesis of a Novel Pyrrolidine‐Based Peptide Nucleic Acid that Contains Tertiary Amines in the Main Chain and Its Internalization into Cells.
Authors: Kitamatsu Mizuki , Kashiwagi Tomoko , Matsuzaki Rino , Sisido Masahiko 
Published: August 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Synthesis and Characterization of a C(6) Nucleoside Analogue for the in vivo Imaging of the Gene Expression of Herpes Simplex Virus Type‐1 Thymidine Kinase (HSV1 TK).
Authors: Johayem Anass , Raic‐Malic Silvana , Lazzati Katia , Schubiger Pius A. , Scappozza Leonardo , Ametamey Simon A. 
Published: August 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Microwave‐Assisted Organic Synthesis of 3‐(D‐gluco‐Pentitol‐1‐yl)‐1H‐1,2,4‐triazole.
Authors: El Ashry E. S. H. , Awad L. F. , Hamid H. M. Abdel , Atta A. I. 
Published: August 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
An Industrial Process for Selective Synthesis of 7‐Methyl Guanosine 5′‐Diphosphate: Versatile Synthon for Synthesis of mRNA Cap Analogues.
Authors: Kore Anilkumar R. , Parmar Gaurang 
Published: August 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Synthesis and Antiviral Evaluation of Novel Open‐Chain Analogues of Neplanocin A.
Authors: Hong Joon Hee , Kim So‐Young , Oh Chang‐Hyun , Yoo Kyung Ho , Cho Jung‐Hyuck 
Published: August 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
A New Flavanone from the Wood of Amorpha fruticosa L.
Authors: Lee Hyun‐Jung , Lee Oh‐Kyu , Kwon Yeong‐Han , Choi Don‐Ha , Kang Ha‐Young , Lee Hyeon‐Yong , Paik Ki‐Hyon , Lee Hak‐Ju 
Published: August 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Investigation on the Distribution of Rare Earth Ions in Strontium Aluminate Phosphors.
Authors: Luo Xixian , Cao Wanghe , Xiao Zhiguo 
Published: August 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Highly‐Quality Sodium Rare‐Earth Fluoride Nanocrystals: Controlled Synthesis and Optical Properties.
Authors: Mai Hao‐Xin , Zhang Ya‐Wen , Si Rui , Yan Zheng‐Guang , Sun Ling‐dong , You Li‐Ping , Yan Chun‐Hua 
Published: August 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Solid Acid Catalyzed Esterification of Amino Acids and Other Bio‐Based Acids
Authors: Asthana N. S. , Zhang Z. , Miller Dennis J. 
Published: August 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Zirconocene‐Mediated Deoxygenative Ring Contractions of Vinyl‐Substituted Carbohydrates: An Expedient Route to Enantiomerically Pure, Densely Functionalized 4‐to‐8‐Membered Carbocycles
Authors: Paquette Leo A. 
Published: August 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Synthesis of Ferrocenyl Deoxyribonucleic Acids (DNAs) and Their Application to Electrochemical Gene Detection
Authors: Mukumoto Kosuke , Takenaka Shigeori 
Published: August 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
How to Control NO Production in Cells: Nω,Nω‐Dimethyl‐L‐arginine Dimethylaminohydrolase as a Novel Drug Target
Authors: Knipp Markus 
Published: August 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
FlexNovo: Structure‐Based Searching in Large Fragment Spaces
Authors: Degen Jörg , Rarey Matthias 
Published: August 2006

AbstractWe present a new molecular design program, FlexNovo, for structure‐based searching within large fragment spaces following a sequential growth strategy. The fragment spaces consist of several thousands of chemical fragments and a corresponding set of rules that specify how the fragments can be connected. FlexNovo is based on the FlexX molecular docking software and makes use of its incremental construction algorithm and the underlying chemical models. Interaction energies are calculated by using standard scoring functions. Several placement geometry, physicochemical property (drug‐likeness), and diversity filter criteria are directly integrated into the “build‐up” process. FlexNovo has been used to design potential inhibitors for four targets of pharmaceutical interest (dihydrofolate reductase, cyclin‐dependant kinase 2, cyclooxygenase‐2, and the estrogen receptor). We have carried out calculations using different diversity parameters for each of these targets and generated solution sets containing up to 50 molecules. The compounds obtained show that FlexNovo is able to generate a diverse set of reasonable molecules with drug‐like properties. The results, including an automated similarity analysis with the Feature Tree program, indicate that FlexNovo often reproduces structural motifs as well as the corresponding binding modes seen in known active structures.
Phosphopeptide Ligands of the SHP‐1 N‐SH2 Domain: Effects on Binding and Stimulation of Phosphatase Activity
Authors: Hampel Kornelia , Kaufhold Ina , Zacharias Martin , Böhmer Frank D. , Imhof Diana 
Published: August 2006

AbstractSrc homology 2 (SH2)‐domain‐mediated interactions with phosphotyrosine (pY)‐containing ligands are critical for the regulation of SHP‐1 phosphatase activity. Peptides based on a binding site from receptor tyrosine kinase Ros (EGLN‐pY2267‐MVL, 1) have recently been shown to bind to the SHP‐1 N‐terminal SH2 domain (N‐SH2) with considerably high affinity. In addition, two peptides cyclized between positions −1 and +2 relative to pY (EGLc[K(COCH2NH)pYMX]L‐NH2, 2: X=D, 3: X=E) bound to the N‐SH2 domain, but did not activate the enzyme and even partially prevented stimulation of SHP‐1 activity by the physiological ligand 1. These findings prompted us to further examine the determinants for optimal binding to the N‐SH2 domain and for the stimulation and inhibition of SHP‐1 activity. Herein we demonstrate that combining the preferred residues in both pY+1 (such as Phe or norleucine, Nle) and pY+3 (such as homophenylalanine, Hfe) leads to highly efficient activating ligands of SHP‐1. Particularly in the context of the cyclic peptides 7 (EGLc[K(COCH2NH)pYFD]Hfe‐NH2) and 8 (EGLc[K(COCH2NH)pYNleD]HfeL‐NH2), the incorporation of these residues resulted in high‐affinity ligands with a significantly increased ability to stimulate SHP‐1 activity. We suggest that different binding modes (according to consensus sequences class I and II) are responsible for obtaining either activating (7 and 8) or nonactivating (2 and 3) ligands. Peptides such as 7 and 8 that bind in the extended fashion of the type II mode activate the phosphatase through complete filling of the cavity for pY+3. In contrast, peptides such as 2 and 3 that bind in the class I mode do not activate the enzyme because they allow more conformational space at pY+3. Therefore, their binding does not force the conformational transition necessary to trigger the dissociation of N‐SH2 and the catalytic domain.
The evolutionary psychology of left and right: Costs and benefits of lateralization
Authors: Vallortigara Giorgio 
Published: August 2006

AbstractWhy do the left and right sides of the vertebrate brain play different functions? Having a lateralized brain, in which each hemisphere carries out different functions, is ubiquitous among vertebrates. The different specialization of the left and right side of the brain may increase brain efficiency—and some evidence for that is reported here. However, lateral biases due to brain lateralization (such as preferences in the use of a limb or, in animals with laterally placed eyes, of a visual hemifield) usually occur at the population level, with most individuals showing similar direction of bias. Individual brain efficiency does not require the alignment of lateralization in the population. Why then are not left‐ and right‐type individuals equally common? Not only humans, but most vertebrates show a similar pattern. For instance, in the paper I report evidence that most toads, chickens, and fish react faster when a predator approaches from the left. I argue that invoking individual brain efficiency (lateralization may increase fitness), evolutionary chance or direct genetic mechanisms cannot explain this widespread pattern. Instead, using concepts from mathematical theory of games, I show that alignment of lateralization at the population level may arise as an “evolutionarily stable strategy” when individually asymmetrical organisms must coordinate their behavior with that of other asymmetrical organisms. Thus, the population structure of lateralization may result from genes specifying the direction of asymmetries which have been selected under “social” pressures. © 2006 Wiley Periodicals, Inc. Dev Psychobiol 48: 418–427, 2006.
Cholesterol metabolism during cell growth: Which role for the plasma membrane?
Authors: Batetta Barbara , Sanna Francesca 
Published: August 2006

AbstractParenchyma proliferation is accompanied by a peculiar modification of the cholesterol metabolism involving both the growing tissue and the plasma compartment. The increase of cholesterol synthesis and uptake has been largely described in the literature and mainly ascribed to the increased requirement of cholesterol for new membrane biogenesis. The dramatic reduction of cholesterol efflux, which probably contributes to the increase of cholesterol esterification and accumulation, has also been largely described, although, further to acting as a prompt pool for membrane biogenesis requirements, its significance and possible influence on cholesterol homeostasis during growth has been almost completely neglected. In this short review, the most widely known modifications and new insights into the cholesterol metabolism during the growth of normal and tumoral cells will be discussed. Particular attention will be paid to the most widely known modifications of cholesterol storage and efflux. The possible implication of proteins in membrane cholesterol translocation causing cholesterol to be directed towards the ER for esterification by ACAT rather than being released by the appropriate external acceptor, i.e. HDL, during proliferation will be discussed.
A new species of Audouinella BORY (Audouinella patelii sp. nova) (Arcrochaetiaceae, Rhodophyta) from Kerala, India
Authors: Shaji C. 
Published: August 2006

AbstractA new bluish species of Audouinella – A. patelii sp. nova – is reported and described from Kerala, India. It differs from its congeners in its over all dimensions, morphology of prostrate system, presence of hairs and rhizoids. It reproduces only by monospores formed singly in unilateral, solitary, sessile, spherical sporangia. (© 2006 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
Variation in fruit and seed morphology, germination and seedling behaviour of some taxa of Ipomoea L. (Convolvulaceae)
Authors: Ogunwenmo K. O. 
Published: August 2006

AbstractFruit and seed morphology, germination and seedling behaviour of 13 taxa of Ipomoea were investigated. Seed and fruit characters were used to construct identification key to the taxa of Ipomoea studied. Mechanical scarification increased seed germination from 35% to 100%. Seeds of Ipomoea pileata subsp. uniflora, I. cairica var. cairica, I. pes‐caprae subsp. brasiliensis and I. carnea subsp. fistulosa observed a period of dormancy ranging from three to over six months in soil. The first foliage leaf appeared between the fith and twelth day of cotyledon emergence from the soil. Growth rate (measured by the rate of leaf productuion over time) was highest in I. quamoclit and least in I. asarifolia . The time and leaf stage at which stem became decumbent varied among the taxa. The truncate leaf bases of first and second leaves of I. ugborea and I. obscura were probably more primitive than the common subsequent and adult cordate leaves of most Ipomoea taxa and suggest common ancestry of the two species. (© 2006 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
Zygospore formation of four rare desmids from Kerala, India
Authors: Panikkar M. V. N. , Krishnan Sreeja 
Published: August 2006

AbstractZygospore formation of four rare taxa of desmids are described. The species include Cylindrocystis brebissonii var. minor West & G.S.West, Penium spinospermum Joshua, Actinotaenium obcuneatum (W.West) Teiling and A. inconspicuum (West & G.S.West) Teiling collected from different places of Wyanad District of Kerala, India. (© 2006 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
Some new taxa of Astragalus L. (Leguminosae) from China and Nepal
Authors: Xu L. R. , Podlech D. 
Published: August 2006

AbstractDuring the work on the genus Astragalus for the Flora of China, some more new species could be found among the unnamed material from the herbaria of Beijing and Kunming. Furthermore a new section had to be described. They are described here: Sect. Poliothrix: A. blandulus, A. hysophilus, A. jumlaensis, A. montivagus, A. oreocharis, A. praeteritus, A. yutaniensis; Sect. Pseudosesbanella sect. nova: A. notabilis. (© 2006 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
New records of Clonostachys epichloë, a mycoparasitic fungus on the grass‐parasitic ascomycete Epichloë typhina for Europe
Authors: Kirschner R. 
Published: August 2006

AbstractA mycoparasitic hyphomycete on the grass‐parasitic ascomycete Epichloë typhina from Germany was identified as Clonostachys epichloë Schroers with morphological and molecular methods. A delicately balanced mutualism is known for the host fungus E. typhina and flies of the genus Botanophila . Studies of type material of Sphacelia typhina subsp. aeruginosa Sacc. collected in France in the 19th century revealed the synonymy of this taxon with Clonostachys epichloë, hitherto reported only for America and Asia under this name. Since C. epichloë apparently is highly host‐specific and more common in Europe than previously known, it might benefit from this mutualism and reduce the development of E. typhina as well as the associated Botanophila flies. (© 2006 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
Structure and development of the branching system in Melica sarmentosa NEES (Poaceae)
Authors: Perreta M. G. , Vegetti A. C. 
Published: August 2006

AbstractThe branching system of cultivated and wild populations of the climbing grass Melica sarmentosa Nees is described on the basis of cultivated and field plant observation. Two types of axes are recognized, namely, ‘basal climbing axes’ and ‘distal climbing axes’. These axes differ in position and morphology and show a particular distribution of branching and branch repression zones associated with their climbing habit. The branching system of the plant can be summerized by the following traits: (1) limited production of innovation axes (basal climbing axes); (2) vigorous development of such axes, which produce a large number of internodes as well as profuse distal branching (distal climbing axes, enrichment shoots), and consequently, (3) remarkable ability of the distal region of the plant for environmental exploration. (© 2006 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)