bluuebunny/crossref_metadata_2025_split huggingface dataset:
Food hypersensitivity in 20 dogs with skin and gastrointestinal signs
Authors: Paterson S. 
Published: April 2008

ABSTRACTCanine food allergy can be defined as a non‐seasonal, pruritic skin disorder of dogs that is associated with the ingestion of a substance found in the dog's diet. This study records the use of a proprietary dried fish, corn and soyabased diet for the investigation and maintenance of food allergic dogs when fed initially as a restricted allergen diet and then as a maintenance diet after challenge. All the dogs showed evidence of pruritic skin disease and in addition demonstrated gastrointestinal signs. These included the presence of faecal mucus and blood, tenesmus and increased faecal frequency; all the signs associated with colitis. Both cutaneous and gastrointestinal signs resolved when an elimination diet was fed and could be reproduced when the animal was appropriately challenged. Ten dogs were trailed on a home cooked diet of fish and potato and 10 dogs on the proprietary complete food. All the dogs were challenged to identify their food allergies. Nineteen of the dogs have subsequently been successfully maintained on the proprietary food.
Medial displacement of the tendon of origin of the biceps brachii muscle in 10 greyhounds
Authors: Boemo C. M. , Eaton‐Wells R. D. 
Published: April 2008

ABSTRACTThe history, clinical signs and treatment of 10 greyhounds with medial displacement of the tendon of origin of the biceps brachii muscle secondary to rupture of the transverse humeral ligament are described. The aetiology of the condition and the prognosis for return to racing are discussed.
Inheritance of histiocytosis in Bernese mountain dogs
Authors: Padgett G. A. , Madewell B. R. , Keller E. T. , Jodar L. , Packard M. 
Published: April 2008

ABSTRACTOne hundred and twenty‐seven cases of histiocytosis in Bernese mountain dogs (BMD) were evaluated to determine if the tumour is inherited. Family data ruled out autosomal recessive, autosomal dominant and sex‐linked modes of inheritance. The trait was determined to be inherited with a polygenic mode of inheritance. The salient points permitting this conclusion are: pedigrees developed from independently selected propositi link up allowing the tracing of all cases through several generations; multiple cases occur in the same litter; multiple cases have been produced by given dams and sires; there is a higher frequency of the disease among offspring of affected parents when compared to offspring of normal parents that produced histiocytosis and all offspring in the general population of BMDs; the fact that histiocytosis is common in BMDs and rare in eight other breeds and accounts for 25·4 per cent of the 500 tumours studied in this breed. The heritability of this trait was calculated to be 0·298.
Vitamin Independent coagulopathy in a British Devon rex cat
Authors: Littlewood J. D. , Shaw S. C. , Coombes L. M. 
Published: April 2008

ABSTRACTDeficiencies of the vitamin K‐dependent coagulation factors were identified in a Devon rex cat which had bled after castration. Haemorrhage was controlled by plasma transfusion. Clotting times were normalised by oral administration of vitamin K. This report confirms the existence of this bleeding disorder in a Devon rex cat in the United Kingdom.
Canine eosinophilic folliculitis and furunculosis in three cases
Authors: Curtis C. F. , Bond R. , Blunden A. S. , Thomson D. G. , McNeil P. E. , Whitbread T. W. 
Published: April 2008

ABSTRACTThe historical, clinical and histopathological features of three dogs with eosinophilic folliculitis and furunculosis are described. The disease was characterised by the rapid development of pruritic, papular, pustular and ulcerative lesions on the dorsum of the muzzle. Skin lesions were confined to the face in two cases. The third dog had more generalised pustular lesions. Skin biopsy specimens showed marked eosinophil infiltration particularly centred on pilosebaceous units. Dermal collagen necrosis was evident in two cases. Similar facial lesions have previously been described as ‘nasal pyoderma’. The three dogs failed to respond to initial antibacterial therapy but showed a rapid clinical response when prednisolone was given orally at doses ranging from 1 to 2‐2 mg/kg, in addition to the antibacterial therapy, suggesting that glucocorticoids are indicated for the treatment of eosinophilic folliculitis and furunculosis. The aetiology of the disease was not determined.
Unilateral arytenoid lateralisation and extra‐luminal polypropylene ring prostheses for correction of tracheal collapse in the dog
Authors: White R. N. 
Published: April 2008

ABSTRACTThe surgical repair of tracheal collapse in 25 dogs is described. The initial presenting signs included coughing, dyspnoea, gagging, retching, exercise intolerance, cyanosis and collapse. Diagnosis was based upon the clinical signs, plain radiography and tracheal endoscopy. The collapse was corrected by the application of a number of extraluminal polypropylene prosthetic rings applied to the affected trachea. Additionally, a left arytenoid lateralisation was also performed. The perioperative complication rate was approximately 4 per cent, while the success rate was 75 per cent. The technique reduces the likelihood of catastrophic postoperative complications associated with iatrogenic laryngeal paralysis which is a possible complication of placement of extraluminal tracheal support devices.
Evaluation of the long‐acting somatostatin analogue Octreotide in the management of insulinoma in three dogs
Authors: Simpson K. W. , Stepien R. L. , Elwood C. M. , Boswood A. , Vaillant C. R. 
Published: April 2008

ABSTRACTThe response of dogs with insulinoma to surgical and medical management is variable, with the majority developing intractable hypoglycaemia. A long‐acting somatostatin analogue, Octreotide (SMS 201–995; Sandostatin) has been useful in the management of hypoglycaemia in humans with insulinoma, and preliminary reports suggest a beneficial clinical response in dogs with insulinoma. The present study objectively evaluated Octreotide in the management of three dogs with immunohistochemically confirmed insulinoma. Octreotide had no benefit over placebo, and little effect on circulating glucose and insulin concentrations despite clearly detectable plasma concentrations of Octreotide. No clinical improvement was apparent in two dogs given Octreotide over a period of two and three weeks. These results contrast with the positive clinical responses noted previously and indicate that further placebo controlled, objective studies are necessary before clear statements on the treatment of insulinoma with Octreotide are made.
Writing and publishing a paper in a veterinary journal
Authors: Mason I. S. 
Published: April 2008

ABSTRACTThe aim of this article is to give a brief guide to scientific writing to encourage more clinicians to take the plunge and write up that unusual case or present the results of their experience with a new treatment or surgical technique. Its target audience is the practitioner who wishes to publish clinical material and the young academic, clinical resident or research fellow. Both groups require guidance in the early days of their publishing career.
Use of monoclonal antibodies for detecting T brucei brucei infection in splenectomised dogs
Authors: Egbe‐Nwiyi T. N. , Antia R. E. 
Published: April 2008

ABSTRACTA monoclonal antibody against a plasma membrane antigen of Trypanosoma rhodesiense was used for the detection of T brucei group‐specific circulating antigen in 24 adult local dogs experimentally infected with T brucei brucei strain 8/18. Ten of the dogs were splenectomised and the remainder non‐splenectomised (intact). Five dogs each from the splenectomised and intact groups were inoculated intravenously with try‐panosomes. The infected dogs developed trypanosomiasis between days 4 and 8 after infection. The circulating antigens were detected as early as six days after infection and remained high until two weeks after treatment, when the circulating antigen declined. The detection of the antigens showed the existence of infection unlike the antibody test. The treatment of the infected dogs with diminazene aceturate (Berenil; Hoechst) at a dose of 7‐0 mg/kg on day 21 after infection cleared all the parasites but elevated the circulating antigen levels. The antigen capture enzyme‐linked immunosorbent assay is a useful diagnostic tool for complementing parasitological diagnosis, for detecting infection in the field and for ascertaining the efficacy of trypanocidal drugs.
Systemic histiocytosis in the Bernese mountain dog
Authors: Paterson S. , Boydell P. , Pike R. 
Published: April 2008

ABSTRACTSystemic histiocytosis is a rare familial histiocytic disorder seen in the Bernese mountain dog. This article documents six confirmed cases of the disease seen at the Animal Medical Centre between June 1992 and June 1994 and describes the different presentations of the disease, response to therapy and progression. Three of the dogs are still alive; of these, two are in remission six and 18 months later and in one case the owner refused treatment. Three of the cases were euthanased for humane reasons.
Distant abdominal and thoracic pedicle skin flaps for treatment of distal limb skin defects
Authors: Lemarié R. J. , Hosgood G. , Read R. A. , Lewis D. D. , Bellah J. R. , Salisbury S. K. , Goldsmid S. 
Published: April 2008

ABSTRACTThe treatment of large skin defects of the distal limbs of dogs and cats can be difficult due to the lack of skin available for primary wound closure or the creation of local skin flaps. Distant pedicle skin flaps provide an acceptable alternative for wound closure with full thickness skin and provide a cosmetic result. Fourteen animals (10 dogs and four cats) that had distant pedicle skin flaps are reviewed. The technique allowed 100 per cent wound coverage in 10 of 14 animals and greater than 95 per cent skin flap survival occurred in 12 of 14 animals. Complications associated with the procedure were most commonly wound infection and partial suture line dehiscence, however these did not detract from the final outcome. Flap release was in one or two stages, however the outcomes did not appear to be affected by the release protocol.
Priapism in seven cats
Authors: Gunn‐Moore D. A. , Brown P. J. , Holt P. E. , Gruffydd‐Jones T. J. 
Published: April 2008

ABSTRACTPriapism (persistent and painful erection) is an uncommon disorder in cats and dogs. This report describes the clinical and pathological features of seven cases of priapism in cats. Six of the cases were Siamese cats, and in four of them the priapism developed after attempted mating with an oestrus female, despite three of them having been neutered. Five cats were treated by perineal urethrotomy, which was successful in four. In five of the six amputated specimens, thrombosis of the corpus cavenosum was evident.
Omental pedicle used to manage a large dorsal wound in a dog
Authors: Smith B. A. , Hosgood G. , Hedlund C. S. 
Published: April 2008

ABSTRACTAn eight‐year‐old miniature schnauzer was presented with full thickness skin necrosis over most of the back, probably caused by a chemical burn. Management consisted of debridement, bandaging, hyperbaric oxygen therapy, topical application of tris‐EDTA and oral administration of antimicrobials. A pedicle created from the greater omentum was used to fill the wound and provide a vascular bed for a full thickness meshed skin graft. Despite epidermal loss from the majority of the graft, the wound healed with acceptable appearance and function. This is the first clinical case described in the veterinary literature using an omental pedicle to prepare a free skin graft bed.
Acute intrinsic renal failure and blood coagulation disorders after a snakebite in a dog
Authors: Puig J. , Vilafranca M. , Font A. , Closa J. , Pumarola M. , Mascort J. 
Published: April 2008

ABSTRACTAcute intrinsic renal failure was diagnosed in a two‐year‐old, male, German shepherd dog following a Vipera aspis bite. Clinical signs included depression, hypersalivation, vomiting, tachypnoea, abdominal pain, splenomegaly, oliguria with haematuria and haemolysed serum. Leucocytosis with a shift to the left, thrombocytopenia, prolonged coagulation times (activated partial thromboplastin time, prothrombin time and thrombin time), hypofibrinogenaemia, azotaemia and hyposthenuria were the most prominent laboratory abnormalities. Histopathological evaluation of the kidneys showed a discrete glomerular hypercellularity, mesangial lysis and renal tubules filled with many hyaline casts and some necrotic cells.
Intrathoracic tracheal avulsion in three cats
Authors: White R. N. , Milner H. R. 
Published: April 2008

ABSTRACTThe surgical repair of complete intrathoracic tracheal avulsion in three cats is described. The initial presenting signs included dyspnoea, exercise intolerance and exertional cyanosis. Diagnosis was based upon the clinical signs, survey radiography and tracheal endoscopy. The ruptures were repaired via a right lateral thoracotomy made at the third or fourth intercostal interspace. Abnormal trachea was resected and a standard tracheal anastomosis was performed. Surgical results were considered excellent in all cases.
Comparison of hemilaminectomy and dorsal laminectomy for thoracolumbar intervertebral disc extrusion in dachshunds
Authors: Muir P. , Johnson K. A. , Manley P. A. , Dueland R. T. 
Published: April 2008

ABSTRACTNeurological improvement after decompressive surgery, without routine therapeutic or prophylactic disc fenestration, was evaluated retrospectively in a consecutive series of 93 dachshunds with thoracolumbar disc extrusion. In 24 per cent of procedures, deep pain sensation was not elicited in at least one hind paw before surgery. Median neurological status one to seven days after surgery, at the time of discharge, was significantly improved after hemilaminectomy compared with dorsal laminectomy (P < 0·05). After hemilaminectomy, deep pain sensation was not elicited in one or both hind paws of 8 per cent of dogs in which pain sensation was elicited before surgery, compared with 21 per cent after dorsal laminectomy (P > 0·05). Improvement in neurological grade at follow‐up examination two to 12 weeks after hemilaminectomy was not significantly different compared with dorsal laminectomy (P > 0·05). Of dogs which were unable to walk before surgery, 83 per cent regained the ability to walk after hemilaminectomy, compared with 74 per cent after dorsal laminectomy (P > 0·05). In both groups, 50 per cent of dogs in which deep pain sensation was abnormal before surgery eventually regained the ability to walk after surgery (P = 1). One to two years after the first operation, a second laminectomy was performed in only 5 per cent of dogs because of extrusion of a different intervertebral disc which had not been fenestrated.
Subclinical versus clinical hepatitis in the dobermann: evaluation of changes in blood parameters
Authors: Speeti M. , Ihantola M. , Westermarck E. 
Published: April 2008

ABSTRACTConcentrations of the enzymes alanine aminotransferase (ALT) and alkaline phosphatase (AP) were determined in blood samples from 626 randomly selected clinically healthy dobermann. ALT levels greater than three times the normal upper value were detected in 55 dogs. These dogs were selected for further investigation; the owners of 23 of the dogs allowed a liver biopsy to be performed. Histopathological examination revealed various degrees of hepatitis and excessive amounts of copper in 21 of the dogs. These cases, referred to as subclinical dobermann hepatitis (DH), were selected for a follow‐up investigation in which the clinical signs and serum parameters (ALT, AP and bilirubin) were studied for a period of three to 48 months. Serum parameters of those with subclinical DH were compared with blood samples collected from 22 dogs with clinical DH. Individual dogs showed great variation in the levels of ALT and AP between consecutive serum samples. These enzyme levels never, however, fell to the normal range. During the subclinical stage no statistically significant (P>0–05) change occurred in the concentrations of ALT or AP. When dogs with subclinical DH were compared with dogs with clinical DH, there was no statistically significant (P>0–05) difference in ALT levels, whereas AP concentrations were significantly (P<0001) higher among clinically affected dogs. Elevated levels of bilirubin were detected almost exclusively in dogs with clinical DH. After the onset of clinical signs there was a decrease in the ALT levels and an increase in AP concentrations as the disease progressed, but the changes were not statistically significant (P>0–05).
Partial cystectomy for urinary bladder neoplasia: surgical technique and outcome in 11 dogs
Authors: Stone E. A. , George T. F. , Gilson S. D. , Page R. L. 
Published: April 2008

ABSTRACTPartial cystectomy was performed in 11 dogs with bladder neoplasia (10 with transitional cell carcinoma and one with rhabdomyosarcoma). Between 40 and 70 per cent of the bladder was excised during the partial cystectomies. In eight dogs, all the grossly visible tumour was excised but on histopathological examination of the excised tissue, neoplastic tissue was found to extend to the surgical margins in four of these dogs. A ureteral stoma was excised with the tumour in four dogs necessitating ureteral reimplantation; one dog had both ureteral stomas excised and bilateral ureteral reimplantation. The bladder incision dehisced in two dogs, necessitating a second surgery. Six dogs were polla‐kiuric after surgery. Pollakiuria resolved within two months in four dogs and persisted in two dogs. None was incontinent. Local tumour recurrence was suspected in nine dogs based on imaging studies and confirmed in five dogs during post mortem examination. Five dogs were euthanased two to seven months after surgery. Six dogs survived at least one year, two of these dogs remain alive at 17 and 27 months after surgery. It is concluded that partial cystectomy may provide local control of bladder neoplasia.
Gastroesophageal intussusception in a young German shepherd dog
Authors: v. Werthern C. J. , Montavon P. M. , Flückiger M. A. 
Published: April 2008

ABSTRACTA gastro‐oesophageal intussusception in a female, six‐week‐old German shepherd dog was treated surgically with success. The dog was presented with acute dyspnoea and signs of shock. After laparotomy, the herniated organs were reduced from the lumen of the oesophagus into the abdomen and an imbrication of the oesophageal hiatus, an appositional fundoplica‐tion and a left‐sided incisional fundopexy were performed. The dog made an uneventful recovery. Eighteen months after surgery the dog is still alive, with no clinical signs despite the persistent presence of megaoesophagus.
Practical use of a combination of a dopamine agonist and a synthetic prostaglandin analogue to terminate unwanted pregnancy in dogs
Authors: Onclin K. , Verstegen J. P. 
Published: April 2008

ABSTRACTThe combination of a dopamine agonist, caber‐goline, and a synthetic analogue of prostaglandin F2a, cloprostenol, was used to induce termination of pregnancy from day 25 after the estimated luteinising hormone surge (day 27 ± 4 after the first mating) in five mature beagle bitches. Caber‐goline was administered orally at 5 μg/kg daily and cloprostenol was injected subcutaneously at 1 μg/kg every other day. Treatment efficacy, in terms of pregnancy termination, was 100 per cent. Termination always took place by resorption of the fetuses. No side effects were observed. A mean of three injections of cloprostenol and nine days of cabergoline treatment was necessary to eliminate all signs of gestation. Termination was in each case accompanied by a decline in plasma progesterone (to less than 1 ng/ml) within 72 hours of initiation of treatment. In a control group of five, untreated bitches, plasma progesterone remained elevated throughout a corre‐
Fibrocartilaginous embolism in a cat
Authors: Scott H. W. , O'Leary M. T. 
Published: April 2008

ABSTRACTA nine‐year‐old cat was presented with a history of an acute onset of paraplegia. On the basis of the neurological examination, the lesion was localised between the fourth lumbar and third sacral segments (L4 to S3) of the spinal cord. Investigations included radiography, myelography, cerebrospinal fluid analysis, routine haematology and biochemistry, feline leukaemia virus testing and urinalysis. A definitive diagnosis was not achieved and the cat was euthanased 12 days after presentation. Post mortem examination revealed infarction of the spinal cord secondary to fibrocartilaginous embolisation. This is the first reported case of fibrocartilaginous embolism in the cat in the UK.
Maxillectomy and targeted radionuclide therapy with 153Sm‐EDTMP in a recurrent canine osteosarcoma
Authors: Moe L. , Boysen M. , Aas M. , Lønaas L. , Gamlem H. , Bruland Ø. S. 
Published: April 2008

ABSTRACTAn eight‐year‐old dog with a local relapse of an osteosarcoma was treated with partial maxillectomy and systemic radionuclide therapy that involved two injections, 43 and 45 megabec‐querels per kg bodyweight of the bone‐seeking agent samarium‐153‐ethylenediaminetetramethy‐lene phosphonic acid (153Sm‐EDTMP), 15 weeks apart. A transient drop in white blood cell count and platelet count was observed following each 153Sm‐EDTMP treatment. Follow‐up 21 months after surgery revealed no evidence of local recurrence or metastases. The dog was in excellent condition, suffering only minor sequelae from the surgical procedure. Compared with historical controls treated with surgery alone, the combination of surgery and systemic radionuclide therapy seems a promising strategy for the treatment of canine osteosarcoma.
Per rectal portal scintigraphy in the diagnosis and management of feline congenital portosystemic shunts
Authors: Hijfte M. A. Forster‐van , McEvoy F. J. , White R. N. , Lamb C. R. , Rutgers H. C. 
Published: April 2008

ABSTRACTFive cats with a congenital portosystemic shunt (CPSS) were examined using transcolonic portal scintigraphy before and after surgical ligation of the shunting vessel. The mean shunt index before surgery was 52 per cent (range 45 to 61 per cent). Repeat portal scintigraphy, six to eight weeks after surgery, indicated a significant reduction in shunt index (mean 13 per cent, range 5 to 25 per cent) in four cats. In one of these cats a marked reduction in the shunt index, as determined by scintigraphy, preceded normal fasting blood ammonia. In the fifth cat there was no significant change in the shunt index, fasting serum bile acids and blood ammonia six months after surgery, although its clinical signs of hepatic encephalopathy had improved. Portal scintigraphy is useful in the diagnosis of CPSS and enables a quantitative assessment of the effects of surgery and may be a more accurate indicator of the degree of shunting after surgery than blood ammonia and serum bile acids.