bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effects of new calcium channel blocker of niludipine on the coronary hemodynamics, diastolic properties, and metabolic responses to tachycardia stress in patients with coronary disease
Authors: Kurita Akira , Isojima Kazushige , Mizuno Kyoichi , Aozaki Noboru , Kondo Shuji , Hosono Kiyoshi 
Published: March 2007

AbstractA new calcium channel blocker, niludipine, was administered intravenously to nine patients with coronary artery disease in order to investigate its effects on left ventricular systolic and diastolic function, coronary sinus blood flow, and myocardial lactate metabolism. Coronary sinus pacing was performed in all patients and produced angina in six patients. Niludipine increased the resting heart rate from 75 ± 3 beats/min (mean ± SEM) to 82 ± 3 (NS) and decreased the left ventricular systolic pressure from 155 ± 4.7 mm Hg to 134 ± 2.8 (p < 0.05). Coronary sinus blood flow increased by 9%(NS). During pacing after niludipine, clinical improvement occurred in the six patients who had initially experienced angina. The extent of ischemic ST segment depression was decreased (−1.56 ± 0.27 mm to −0.78 ± 0.38, p<0.02) and myocardial lactate metabolism was improved. When pacing was terminated, niludipine suppressed the elevation of left ventricular end‐diastolic pressure compared to pretreatment values (16.2 ± 2.5 mm Hg vs 8.5 ± 0.9, p < 0.05) and decreased the left ventricular time constant T(26.4 ± 3.6 msec to 20.2 ± 2.4, p < 0.05). The results suggest that niludipine appears to be beneficial in reducing systolic and diastolic work of the left ventricle during pacing induced angina without a significant change in total coronary sinus blood flow. Niludipine appears to have less of a hypotensive and reflex tachycardic effect than nifedipine.
Permanent pacemaker implantation in the cardiac catheterization laboratory: The subclavian vein approach
Authors: Hess David S. , Gertz Edward W. , Morady Fred , Scheinman Melvin , Sudduth Bonnie K. 
Published: March 2007

AbstractDuring a 36‐month period, 171 permanent pacemaker procedures were performed in the cardiac catheterization laboratory by invasive cardiologists. This included 111 initial pacemaker system implants, via the percutaneous subclavian vein approach, 45 pulse generator changes, and 15 miscellaneous procedures. In no case did subclavian vein puncture result in pneumothorax, hemothorax, or brachial plexus injury. In patients undergoing initial lead placement, the dislodgment rate was 0.8% over a 16‐month follow‐up period. The reoperation rate for causes other than premature battery depletion was 5.4% during the first 12 months. The implantation of permanent pacemakers can be safely and effectively accomplished by experienced invasive cardiologists in the cardiac catheterization laboratory. In our series not only was continuity of patient care improved, but also medical costs were reduced.
First‐pass radionuclide angiocardiography in the determination of left‐to‐right cardiac shunt site in children
Authors: Tian Jia‐He , Murray I. Provan C. , Walker Brenda , Hoschl Radmil , Choy Daniel , Freeman Anthony 
Published: March 2007

AbstractTo ascertain if the level of a left‐to‐right cardiac shunt can be reliably established by first‐pass radionuclide angiocardiography with 99mTc‐pertechnetate, 102 children have been studied; 19 without a shunt, 26 with an atrial septal defect (ASD), 45 with a ventricular septal defect (VSD), and 12 with a patent ductus arteriosus (PDA). Time‐activity curves were generated over the right atrium and ventricle, and several quantitative parameters were derived from the curves. It was concluded that in the absence of right‐sided valvular incompetence, the time‐activity curves show the greatest abnormality in the cardiac chambers distal to the left‐to‐right shunt. The right ventricular curve is typically altered in ASD but cannot be relied upon to differentiate VSD or PDA. The identification of ASD is assisted by the use of two of the parameters, the count ratio C4:C1 and time ratio T2:T1.
Aneurysm of a saphenous vein bypass graft associated with aneurysms of native coronary arteries
Authors: Bramlet Dean A. , Behar Victor S. , Ideker Raymond E. 
Published: March 2007

AbstractAneurysm formation in saphenous vein aortocoronary bypass grafts is an extremely rare complication of coronary artery bypass surgery. Aneurysms of native coronary arteries are found in a small percentage of patients at autopsy. Reported is a case with multiple coronary artery aneurysms in which a dissecting aneurysm of the saphenous vein bypass graft also developed following coronary artery bypass surgery. This is the first report of such association.
Severe thrombocytopenia as a result of contrast left ventricular angiography
Authors: Wein Paul , Handler Martin , Chadda Kul D. 
Published: March 2007

AbstractA case report of a 29‐year‐old Hispanic male who developed an acute thrombocypenic reaction immediately following a cardiac catheterization using Hypaque‐M radiographic dye. Laboratory studies immediately post‐catheterization revealed a platelet count of 11,000 with a subsequent further drop to a low of 4,000. A need for the prompt identification and possible causes of this unusual reaction are discussed. Recovery occurred following treatment with corticosteroids.
Long‐term survival despite multiple complications of acute myocardial infarction
Authors: Davies A. B. , Hogg M. 
Published: March 2007

AbstractA 71‐year‐old woman sustained an anterior myocardial infarction resulting in a large apical aneurysm, a ventricular septal defect, and mitral regurgitation, which did not incur hospital admission at that time. Surgical repair was successfully performed ten months later because of moderate effort dyspnea and in the assumption that prognosis would be improved.
Use of a personal computer in the measurement, calculation, and reporting of noninvasive cardiac data
Authors: Abdulla Abdulla M. , Henke John S. , Stefadouros Miltiadis A. , Watkins Laurence O. , Frank Martin J. 
Published: March 2007

AbstractEchocardiography, phonocardiography, and carotid pulse tracings enable the cardiologist to measure and calculate over 40 different noninvasive parameters including cardiac chamber size, indices of left ventricular performance, and estimates of mean left atrial pressure. However, the entire procedure requires meticulous measurements and time‐consuming calculations, particularly when some of the data must be corrected for heart rate or body size. Because of this, many busy noninvasive cardiac laboratories routinely calculate only a few select parameters in most patients. To solve this problem, we used a personal computer system and developed a program that allows rapid, accurate measurement, calculation, display, reporting, magnetic storage, and retrieval of noninvasive cardiac data. The computer is not dedicated to these tasks alone and with appropriate software can also be used for other clinical, educational, office management, and research purposes.
Percutaneous vs surgical placement of intra‐aortic balloon assist
Authors: Singh Arun K. , Williams David O. , Cooper George N. , Riley Raymon S. , Karlson Karl E. 
Published: March 2007

AbstractFifty‐three patients required IABP over a one‐year period. The type of insertion (percutaneous vs surgical) was used randomly. The hemodynamic effect, complication rate, and inability to insert the balloon were similar in both groups. Besides less trauma and cost‐effectiveness, the most important advantage of percutaneous over surgical balloon insertion is shorter time interval between decision and insertion which thus allows faster stabilization of ischemic heart patients.
Automated blood pressure measurement during ergometer exercise in children
Authors: Alpert Bruce S. , Flood Nadine L. , Balfour Ian C. , Strong William B. 
Published: March 2007

AbstractThe measurement of systolic and diastolic blood pressure during exercise is often difficult to perform due to patient motion and environmental noise. We evaluated an automated system of blood pressure determination in 121 children undergoing cycle ergometer stress testing. The system (Critikon Model 1165) utilized acoustic transduction, with electrocardiogram gating and microprocessor signal filtering. One observer measured the blood pressure values from the same arm as the automated system; this observer was blinded to the readout of the system. The correlation coefficients for systolic blood pressure at rest, during exercise, and during recovery were all > 0.91, and improved with the use of a stethophone adapter. This system can eliminate intraobserver variation as well as the necessity for the technician or physician to direct attention away from the electrocardiogram and patient during stress testing.
Transseptal left heart catheterization: Utility of a sheath technique
Authors: Laskey Warren K. , Kusiak Victoria , Untereker William J. , Hirshfeld John W. 
Published: March 2007

AbstractThis report describes our experience with a modified sheath transseptal catheter system. The sheath technique allows for introduction of various catheters into the left heart, including a uniquely designed pigtail catheter intended for use with this system. Fifty‐three patients underwent successful transseptal catheterization, 44 of whom had severe native aortic valve stenosis and seven with suspected prosthetic aortic valve dysfunction. The technique provides optimal ventriculographic and hemodynamic information as well as improved access to the left heart in patients with aortic valve disease.
Effects of selective injection of contrast media on coronary artery diameter
Authors: Hill James A. , Feldman Robert L. , Conti C. Richard , Pepine Carl J. 
Published: March 2007

AbstractThe purpose of this study was to quantify the effect of Renografin‐76 on eplcardial coronary artery diameters, during selective coronary anglography. Using 105 mm‐photospot angiograms taken at 0,1, and 5 min, 99 coronary segments from ten patients were measured. Comparing the anglograms at 1 and 5 min to the control anglograms, a7 ± 7% and 6 ± 7% (both p = NS) change in diameter respectively was noted. Comparing the 1 and 5 min anglograms, there was no significant change (‐1 ± 7%). Measurements were found to be very reproducible. This study shows that there is a trend toward dilation of the coronary arteries during selective coronary anglography, but this did not reach statistical significance and probably is not clinically important.
Use of ventriculography in assessing performance and oxygen consumption of the left ventricle: Response to altered afterload
Authors: Bove Alfred A. , McGinnis Andrew W. , Michele John L. 
Published: March 2007

AbstractUsing ventriculography, we assessed the relationship between performance, blood flow, and oxygen consumption of the left ventricle in seven anesthetized dogs. Ventricular loading was varied between increased and decreased afterload by intra‐aortic infusion of angiotensin and acetylcholine. Intact ventricular performance was measured by computer‐based analysis of biplane left ventriculograms. Myocardial blood and flow distribution was determined by radioactive microspheres, and oxygen consumption was measured by coronary arteriovenous oxygen difference times blood flow. When left ventricular systolic pressure rose, tension‐time index, stress‐time index, stroke work, and minute work derived from the ventriculogram increased significantly; end diastolic volume increased; and ejection fraction decreased. Inverse responses occurred to a smaller degree when left ventricular pressure was reduced. With increased pressure, myocardial blood flow and oxygen consumption changed proportionately to minute work. Correlation coefficients between oxygen consumption and stroke work (0.782), oxygen consumption and minute work (0.769), oxygen consumption and tension‐time index (0.792), and between oxygen consumption and stress‐time index (0.740) all indicate that performance measures obtained from ventriculograms can be used to estimate changes in oxygen consumption during acute afterload changes. These measurements can be applied to data obtained from clinical catheterization studies in man and suggest that changes in myocardial performance and oxygen consumption can be estimated from ventriculographic data.
Right ventricular size and function: The discrepancy between cardiac blood pool imaging techniques
Authors: Hooper Wayne , Horn Mathew , Moser Kenneth , Neveu Connie , Costello Dennis , Bhargava Valmik , Taylor Andrew , Slutsky Robert 
Published: March 2007

AbstractThe purpose of this study was to evaluate a number of equilibrium radionulide methods for analyzing right ventricular size and function, in an attempt to determine if any of a variety of approaches could accurately characterize right ventricular hemodynamics. Fourteen patients being clinically evaluated for coronary artery disease (N = 9), congestive cardiomyopathy (N = 2), valvular disease (N = 2), or intracardiac shunts (N = 1) underwent biplane contrast right ventriculography following gated blood pool imaging. Four radionuclide techniques were examined and included: (1) a semiautomatic edge‐detection algorithm using a variable right ventricular region‐of‐interest and a right ventricular apical end diastolic background; (2) a fixed right ventricular end‐diastolic region‐of‐interest with a C‐shaped background; (3) the same fixed end‐diastolic right ventricular region‐interest with a right ventricular end‐diastolic apical background; and (4) both right ventricular end‐diastolic and end‐systolic regions‐of‐Interest with a background chosen lateral to the left ventricle. Right ventricular end‐diastolic volume was obtained by correcting end‐diastolic counts by frame time, the number of processed heart beats, and blood radioactivity. The results illustrate the wide discrepancy among these methods. The correlation coefficients comparing right ventricular ejection fractions by radlonuclide methods 1 to 4 with contrast ventriculography were 0.23, 0.74, 0.40, and 0.42, respectively. For right ventricular end‐diastolic volumes, the correlation coefficients were 0.90, 0.72, 0.90, and 0.92, respectively. While these techniques may be useful for analyzing serial changes in right heart function and size, further investigation is needed before right ventricular equilibrium radionuclide techniques can be acceptably utilized in clinical practice, particularly in individual subjects.
Coronary artery spasm occurring late after vein graft surgery
Authors: Singh Ram N. , Varat Murray A. 
Published: March 2007

AbstractA patient with classic effort angina and high‐grade, fixed proximal coronary atherosclerosis underwent a single saphenous vein graft to a large, dominant right coronary artery (RCA). After being asymptomatic for 1 1/2 years, she had several episodes of rest angina culminating In Prinzmetal angina and ventricular fibrillation. Electrocardiographic changes occurred in the RCA distribution. Symptoms subsided with oral nifedlpine therapy. Angiography revealed intact vein graft and coronary circulation. The patient has done well for a follow‐up period of 7 months.
Percutaneous transluminal angioplasty of an anomalous left circumflex coronary artery arising from the right sinus of valsalva
Authors: Schwartz Leonard , Aldridge Harold E. , Szarga Carol , Cseplo Rose‐Marie 
Published: March 2007

AbstractThis case report describes a patient with isolated stenosis of an anomalous circumflex artery with evidence of left ventricular lateral wall ischaemia. Percutaneous dilatation of this vessel was successfully performed and was facilitated by removing the tip of a standard guiding catheter permitting selective cannulation of the anomalous ostium. Similar innovations in the standard angioplasty technique may permit its application in other unusual anatomical situations.
Quantitative coronary angiography during intracoronary streptokinase in acute myocardial infarction: How long to continue thrombolytic therapy?
Authors: Feldman Robert L. , Crick William F. , Conti C. Richard , Pepine Carl J. 
Published: March 2007

AbstractAn Intracoronary Infusion of streptokinase is often administered in patients with acute myocardial infarction. To address the question of how long intracoronary streptokinase should be infused, we studied 13 patients with symptoms and electrocardiographic findings suggesting an evolving myocardial infarction. We used subselective catheterization techniques and made quantitative angiographic measurements of the percentage of reduction of coronary artery (CA) diameter before intracoronary streptokinase therapy, immediately after reperfusion was established, and at the completion of streptokinase infusion. Before intracoronary streptokinase and after intracoronary nitroglycerin, nine patients had 100% obstruction of the CA in the “infarct‐related vessel.” In seven patients reperfusion was established (25 ± 21 min, mean ± SD) at which time CA diameter was reduced by 77 ± 22%. The streptokinase infusion was then continued until repeated films (every 10 to 15 min) suggested no further change at the site of CA obstruction (93 ± 68 min). The percentage of CA diameter reduction when streptokinase infusion was discontinued was 55 ± 32%; this value was less (P < 0.05) than that observed early after reperfusion. These data show that after initial reperfusion was achieved by the use of intracoronary streptokinase, additional streptokinase lessened the reduction of CA diameter. Residual thrombus may be present at the narrowed CA site early after reperfusion, and further “cleanup” can be achieved by prolonging streptokinase infusion.
Estimation of mixed venous oxygen saturation
Authors: French William J. , Chang Potter , Forsythe Sarah , Criley J. Michael 
Published: March 2007

AbstractPulmonary artery oxygen saturation (PA) was measured directly and estimated from venal cavae samples in 175 adults without intracardiac shunts to ascertain which of four formulas (MV1, MV2, MV3, or MV4) best estimated mixed venous oxygen saturation. Because the formula MV1, which favored IVC samples, most closely approximated pulmonary artery saturation, we recommend its use to estimate systemic flow in patients with left‐to‐right shunts. In addition, a difference between directly measured PA and calculated MV1 of 6% or greater indicates the presence of a left‐to‐right shunt in 97% of cases.
Massive dilatation of the atria and coronary sinus in a child with restrictive cardiomyopathy and persistence of the left superior vena cava
Authors: Sapire David W. , Casta Alfonso , Swischuk Leonard E. , Casta Daisy 
Published: March 2007

AbstractA two‐year‐old child with massive cardiomegaly was proved to have restrictive cardiomyopathy. A literature search has shown only two other cases of this in young children. All three have had massive biatrial dilatation with nearly normal ventricular function. This case is the first with clearly defined echocardiography and complicating diagnostic features associated with persistence of a left superior vena cava.
Single catheter technique for accurate cardiac outputs from left ventricle
Authors: Sanders Michael , Onah Joseph , Lichstein Edgar , Hollander Gerald , Greengart Alvin , Rivera Marcos 
Published: March 2007

AbstractWe report our experience in cardiac output measurements using a single catheter for left ventricular green dye injection with sampling from the side arm of a femoral artery introducer sheath. This technique is compared to thermal dilution (20 patients) and pulmonary artery green dye injection (20 patients). There were no significant differences between the single catheter left ventricular method and the other two accepted methods for measuring cardiac output.
Catheter for visualization of patent ductus arteriosus
Authors: Endrys Jiří , Horký Josef , Yousof Abdul M. 
Published: March 2007

AbstractWe have developed a new catheter for transvenous angiography in patent ductus arteriosus (PDA) that has given excellent results in 31 patients (age range seven months to 17 years). Optimal selective opacification of PDA is due to maintaining the catheter side holes in close proximity to the PDA and to rapid delivery of relatively large volumes of contrast medium into the ampulla of the PDA without the catheter recolling. The venous route of catheter insertion precludes possible arterial injury.
Nonsurgical technique for removal of catheter fragments from the pulmonary artery
Authors: Tanaka Minoru , Iyomasa Yohtaro 
Published: March 2007

AbstractIn this report the authors describe a new technique for nonsurgical retrieval of an embolized catheter fragment without free ends in the pulmonary artery using a “forceps with three grasping prongs.” This method is extremely promising for retrieval of catheter fragments in the pulmonary artery, especially when the free ends are not accessible.
The minimum error in estimating coronary luminal cross‐sectional area from cineangiographic diameter measurements
Authors: Richard Spears J. , Sandor Tamas , Baim Donald S. , Paulin Sven 
Published: March 2007

AbstractA formal analysis of the error associated with the use of radiographic diameter measurements in estimating the luminal area of an elliptically‐shaped coronary cross‐section was performed. When two views are available, the maximum potential error was found to decrease rapidly as the angle between the views increased to 90°, but this error was small (< 25%) for orthogonal views only for mild degrees of ellipticity (major/minor axis ratio < 2). Since, for each successive doubling of the number of radiographic views, a stepwise reduction in the potential error by an approximate factor of only one‐half was found, a large number of views is required to eliminate the potential error associated with diameter assessment of highly elliptical lumena.
Regional sequential motion in the normal left ventricle: Nonuniform apical motion
Authors: Leighton Richard F. , Dennis Nelson A. , Andrews Lee T. , Gupta Manohara 
Published: March 2007

AbstractTiming of the onset and sequence of systollc regional wall motion was examined in the digitized left ventricular cineanglograms of 13 patients with anglographlcally normal coronary arteries and left ventricular function. Distance‐time curves for anterior and inferior wall segments, the aortic valve plane, and apex point were compared to the volume‐time curve in each ventricle. No significant differences were found in the onset of motion for the wall segments or for descent of the aortic valve where the sequence of motion was generally uniform. At the apex point, however, the onset of motion was significantly delayed. In addition, reduced velocity of motion in the first half of systole was followed by high velocity motion in the latter half. This apparent nonuniform apical motion may be explained by a geometric relationship of normally contracting myocardial wall fibers adjacent to a thin apical point which has relatively little or no contractile motion of its own.