bluuebunny/crossref_metadata_2025_split huggingface dataset:
Silica-Based 1,3-Diphenyl-1,3-Propanedione Composites: Efficient Uranium
Capture for Environmental Remediation
Authors: Al-Anber Mohammed A. , Al-Qaisi Wala' , Al-Momani Idrees F. , Hijazi Ahmed K. , Sobola Dinara , Alhalasah Wasim , Al-Anber Zaid A. 
Published: April 2024

Introduction::
This study synthesizes and characterizes a novel hybrid composite, SGdpm,
to capture UO2
2+ ions from water. The composite has successfully formed by hosting covalently
diphenylmethane-1,3-dione (dpm) within an inorganic silica gel matrix, showing promising potential
for environmental remediation and nuclear waste management.

Methods::
The preparation involved the reaction of tetraethylorthosilicate (TEOS) with diphenylmethane-
1,3-dione (dpm) under acidic conditions, resulting in white solids. The doped composite was
characterized by Fourier Transform Infrared Spectroscopy (FTIR), revealing the presence of siloxane
and Si-O-C bonds. The application of SG-dpm for capturing UO2
2+ ions from water was investigated,
showing a shift in FTIR peaks and confirming the formation of SG-dpm-UO2
2+ as inner-sphere complexes.
Scanning Electron Microscopy (SEM) revealed a non-uniform distribution of particles, essential
for consistent behavior in applications such as adsorption.

Results and Discussion::
Batch sorption experiments demonstrated temperature-dependent sorption
behavior with increased efficiency at higher temperatures (T = 55°C). The study also explored the
influence of pH and initial concentration on UO2
2+ sorption, revealing optimal conditions at pH 5 and
lower initial concentrations (1.0 mg L-1). Kinetic studies using pseudo-second-order models indicated
a high efficiency of UO2
2+ ion removal (99%) as a chemisorption process. Intraparticle diffusion
models highlighted three distinct sorption stages. Sorption isotherm studies favored the Langmuir
model, emphasizing monolayer adsorption. The thermodynamic analysis suggested an endothermic
(ΔH = + 16.120 kJ mol-1) and spontaneous (ΔG = −25.113 to − 29.2449 kJ mol-1) sorption process.
Selectivity studies demonstrated high efficiency in capturing Cu2+, Co2+, and Cr3+ ions, high degree
selectivity of UO2
2+ ions (74%), moderate efficiency for Fe3+ and Zn2+, and lower efficiency for Pb2+,
Ni2+, and Cd2+, and poor efficiency for Mn2+ ions.

Conclusion:
SG-dpm exhibits promising potential for selective UO2
2+ ion removal, demonstrating
favorable characteristics for various applications, including environmental remediation and nuclear
waste management.
Evaluation of an e-Learning Program for Community Pharmacists for Dispensing Emicizumab (Hemlibra) in France: Nationwide Cross-Sectional Study
Authors: Chamouard Valérie , Freyssenge Julie , Clairaz-Mahiou Béatrice , Ferrera Bibas Felicia , Fraticelli Laurie 
Published: April 2024

Background
Since June 2021, patients with hemophilia A with antifactor VIII inhibitors and those with severe hemophilia A without antifactor VIII inhibitors treated with Hemlibra have had to choose between a community or hospital pharmacy. The French reference center for hemophilia developed the HEMOPHAR e-learning program for community pharmacists for dispensing emicizumab.

Objective
This study aims to evaluate the efficiency and safety of this new care pathway by assessing the HEMOPHAR e-learning program.

Methods
The methodology is based on Kirkpatrick’s model for evaluating the immediate reaction of trained community pharmacists (level 1), their level of acquired knowledge (level 2), and their professional practice after 3 months of dispensation (level 3).

Results
The HEMOPHAR e-learning program reached a large audience, with 67% (337/502) of the eligible community pharmacists following it. The immediate reaction was overall satisfying. High rates of engagement were reported with 63.5% (214/337) to 73.3% (247/337) of completed training modules, along with high rates of success with quizzes of 61.5% (174/337) to 95.7% (244/337). We observed that 83.9% (193/230) of the community pharmacists needed less than 2 attempts to pass the quiz of the module related to professional practice, while the other quizzes required more attempts. Advice on compliance and drug interactions were most frequently provided to patients by the community pharmacists.

Conclusions
This study suggests ways to improve the training of community pharmacists and to optimize coordination with treatment centers. This study also reports on the feasibility of switching to a community pharmacy in a secure pharmaceutical circuit, including in the context of a rare bleeding disease.

Trial Registration
ClinicalTrials.gov NCT05449197; https://clinicaltrials.gov/study/NCT05449197

International Registered Report Identifier (IRRID)
RR2-10.2196/43091
The Accuracy of Pulse Oxygen Saturation, Heart Rate, Blood Pressure, and Respiratory Rate Raised by a Contactless Telehealth Portal: Validation Study
Authors: Gerald Dcruz Julian , Yeh Paichang 
Published: April 2024

Background
The traditional measurement of heart rate (HR), oxygen saturation (SpO2), blood pressure (BP), and respiratory rate (RR) via physical examination can be challenging, and the recent pandemic has accelerated trends toward telehealth and remote monitoring. Instead of going to the physician to check these vital signs, measuring them at home would be more convenient. Vital sign monitors, also known as physiological parameter monitors, are electronic devices that measure and display biological information about patients under constant monitoring.

Objective
The purpose of this study was to validate the accuracy of the pulse SpO2, HR, BP, and RR raised by Docsun Telehealth Portal by comparing it with approved medical devices.

Methods
This is a noninvasive, self-check, system-based study conducted to validate the detection of vital signs (SpO2, HR, BP, and RR) raised by Docsun Telehealth Portal. The input for software processing involves facial screening without any accessories on the face, scanning directly through the software application portal. The participant’s facial features are detected and screened for the extraction of necessary readings.

Results
For the validation of HR, SpO2, BP, and RR measurements, the main outcomes were the mean of the absolute difference between the respective investigational devices and the reference values as well as the absolute percentage difference between the respective investigational devices and the reference values. If the HR was within ±10% of the reference standard or 5 beats per minute, it was considered acceptable for clinical purposes. The average absolute difference between the Docsun Telehealth Portal and the reference values was 1.41 (SD 1.14) beats per minute. The mean absolute percentage difference was 1.69% (SD 1.37). Therefore, the Docsun Telehealth Portal met the predefined accuracy cutoff for HR measurements. If the RR was within ±10% of the reference standard or 3 breaths per minute, it was considered acceptable for clinical purposes. The average absolute difference between the Docsun Telehealth Portal and the reference values was 0.86 breaths per minute. The mean absolute percentage difference was 4.72%. Therefore, the Docsun Telehealth Portal met the predefined accuracy cutoff for RR measurements. SpO2 levels were considered acceptable if the average absolute difference between the Docsun Telehealth Portal and the reference values was ±3%. The mean absolute percentage difference was 0.59%. Therefore, the Docsun Telehealth Portal met the predefined accuracy cutoff for SpO2 measurements. The Docsun Telehealth Portal predicted systolic BP with an accuracy of 94.81% and diastolic BP with an accuracy of 95.71%.

Conclusions
The results of the study show that the accuracy of the HR, BP, SpO2, and RR values raised by the Docsun Telehealth Portal, compared against the clinically approved medical devices, proved to be accurate by meeting predefined accuracy guidelines.
Improving Foundational Understanding regarding Facility Transition through a Survey Assessment of Industry Professionals involved in Commercial Building Decommissioning
Authors: Karanja Pauline , Pilkington Stephanie , Smithwick Jake , Mayo Glenda 
Published: April 2024

ABSTRACT
Commercial buildings are asset intensive facilities and therefore have unique challenges in the asset lifecycle management. When procedures and guidelines on decommissioning are not enforced, these buildings can be left unattended for years. As a result, the lack of maintenance may expedite asset deterioration, thus leaving less material salvageable for future use. This study aims to better understand current trends in the decommissioning of commercial buildings by surveying industry professionals across three possible dimensions 1) planned decommissioning, 2) condition assessments on commercial buildings, and 3) current awareness of procedures and guidelines. Through correlation analysis, the study explores how professionals’ roles in the industry relate to these three dimensions, offering valuable insights into the dynamic interplay shaping decommissioning practices. This study analyzes data collected through a Qualtrics survey designed to target construction and facilities management professionals. The 720 respondents were associated with the International Facilities Management Association and the American Institute of Architects. Results of the study show that planning for decommissioning mostly occurs once a building has been vacated or due to reactionary planning in an attempt to save a facility for reuse or remodeling. There is a consensus among the survey respondents that condition assessments on unoccupied/vacated buildings should be conducted annually. Results also indicate that although there are instances where vacated facilities maintained a minimal supply of utilities, there are many instances where facilities have had lights switched off, doors locked, and the building completely shut down. This study provides results that identify key variables as to what may influence how a building is decommissioned and promote standardized decommissioning procedures and guidelines for commercial buildings.
Herbal medicines for treatment of socially significant diseases in current Bulgarian society
Authors: Dimitrova Zheni , Dragoeva Asya , Stoyanov Martin , Koleva Vanya 
Published: April 2024

Abstract
Socially significant diseases are defined as widespread diseases causing great economic, social and demographic damage. Nowadays traditional health practices have gained increasing interest. The aim of this online survey was to establish the knowledge of a random sample of Bulgarian people about traditional medicines in order to find out: 1) the knowledge about the use of medicinal plants for some socially significant diseases; 2) the attitudes of respondents towards the medicinal plants safety; 3) the statement whether the herbs can replace conventional drugs. In present survey the most used medicinal plants reported was Crataegus monogyna Jacq., Zingiber officinale Roscoe, Allium sativum L., Valeriana officinalis L., Sambucus nigra L., Cinnamomum verum J. Presl and Curcuma longa L. Current scientific studies proved appropriate use reports of these plants. One of the reasons for the renewed interest in phytotherapy is the assumption that anything natural is safe, but there are data that herbal chemical constituents could exert toxic effects. The demographic features of our respondents revealed the importance of the level of education for the self-health care. So, more efforts should be focused on the spread of disease prevention information in low educated populations.
Deep reinforcement learning based computing offloading in unmanned aerial vehicles for disaster management
Authors: Kesavan Anuratha , Mohanram Nandhini Jembu , Joshi Soshya , Sankar Uma 
Published: April 2024

Abstract
The emergence of Internet of Things enabled with mobile computing has the applications in the field of unmanned aerial vehicle (UAV) development. The development of mobile edge computational offloading in UAV is dependent on low latency applications such as disaster management, Forest fire control and remote operations. The task completion efficiency is improved by means of using edge intelligence algorithm and the optimal offloading policy is constructed on the application of deep reinforcement learning (DRL) in order to fulfill the target demand and to ease the transmission delay. The joint optimization curtails the weighted sum of average energy consumption and execution delay. This edge intelligence algorithm combined with DRL network exploits computing operation to increase the probability that at least one of the tracking and data transmission is usable. The proposed joint optimization significantly performs well in terms of execution delay, offloading cost and effective convergence over the prevailing methodologies proposed for UAV development. The proposed DRL enables the UAV to real-time decisions based on the disaster scenario and computing resources availability.
Fault sensitivity index-based multi-objective testcase prioritization
Authors: Garg Kamal , Shekhar Shashi 
Published: April 2024

Abstract
Test case prioritization (TCP) is a regression technique that sequences test cases by assigning priority based on specific criteria defined by software testers. Various parameters, such as code coverage, statement coverage, and method coverage, are utilized in Test Case Prioritization (TCP), wherein metaheuristic techniques are widely employed to determine the optimal order of test cases based on these specified parameters. However, simply applying these techniques does not ensure the satisfaction of all the needs of software testers. This paper introduces an empirical study that employs the multi-objective test case prioritization (MOTCP) technique to prioritize the test cases based on target points defined by software testers. The study calculates a Software Complexity Index (SCI) at the code level, identifying fault-prone areas. Furthermore, a Test-case Complexity Index (TCI) is also used for prioritization. The proposed technique incorporates various target points defined by the software tester to calculate SCI and TCI, which serve as our main objectives for TCP. A detailed analysis is also performed to examine the impact of these target points on the generated optimal order of test cases. Finally, the proposed model is compared with other state-of-the-art techniques across various evaluation parameters.
Alternative Treatment of Gonarthrosis: Proximal Fibular Osteotomy
Authors: Gavrilovski Andreja , Dimovska Aleksandra Gavrilovska , Spasov Marko , Kostov Hristijan , Igor Igor Merdzanoski , Jonoski Kire , Trpeski Simon 
Published: April 2024

Abstract

Introduction:
Gonarthrosis is arthrosis of the knee joint, a chronic non-inflammatory disease manifested by progressive destruction of the intra-articular cartilage, accompanied by abnormal formation of the bones form the joint, changes in the synovial membrane and synovial fluid. Gonarthrosis is the most common type of arthrosis. Gonarthrosis can be treated conservatively and operatively. Among well-established surgical options for the treatment of medial gonarthrosis are high tibial osteotomy (HTO), unicompart-mental knee arthroplasty (UKA), and total knee arthroplasty (TKA). Proximal fibular osteotomy (PFO) or superior partial fibulectomy is a relatively recent procedure proposed to reduce knee pain in patients with medial compartment.

Aim:
Our study aims to demonstrate an alternative treatment for gonarthrosis with proximal fibular osteotomy and reduced knee pain in patients with medial compartment osteoarthritis of the knee.

Materials and methods:
At the Department of Orthopedics and Traumatology at J.Z.U “Borka Taleski” Prilep in the period from 2018 to 2021, 14 cases were treated, of which 11 were female and 3 were male. All patients were aged between 62 and 82 years with a mean age of 71.3 years. Patients had a severe degree of gonarthrosis (III/IV) according to Kellgren-Lawrence classification. Arthroscopy was performed in 2 patients. The fibula osteotomy was 7 cm away from the fibular head, with 1 cm resected bone fragment from the fibula.

Results:
The average duration of the surgery was 30 minutes. Patients were followed up on the 7th day, first month, 3 months and 6 months after surgery. The final evaluation of function was done after 6 months by examining the active and passive movements of the knee joint. In all 14 patients we have excellent results with pain reduction, improvement of movement and quality of life.

Conclusion:
Proximal fibular osteotomy is an option for medial compartment osteoarthritis of the knee. Current literature is limited to small case series which report good outcomes in pain reduction, including the correction of varus deformity in medial gonarthrosis. Further studies are needed to determine the place of the PFO in the medial gonarthrosis management algorithm before it can be recommended for routine clinical use.
Respiratory Distress Syndrome (RDS) in Newborns with Hypoxic-Ischemic Encephalopathy (HIE)
Authors: Ristovska Sanja 
Published: April 2024

Abstract
Respiratory distress syndrome (RDS) and hypoxic-ischemic encephalopathy (HIE) are frequent causes of death and disability in neonates. This study included newborns between January 2021 and July 2022 at the University Clinic for Gynecology and Obstetrics, Skopje. Up to date criteria for HIE/RDS for term and for preterm infants as well for the severity of HIE/RDS were used in a comprehensive analysis of cranial ultrasonography, neurological status, neonatal infections, Apgar score, bradycardia and hypotension, X-ray of the lungs, FiO2, acid-base status, assisted ventilation and use of surfactant.
Three groups were created: HIE with RDS (42 babies), HIE without RDS (30 babies) and RDS without HIE in 38 neonates. All newborns with severe (third) degree of HIE died. Intracranial bleeding was found in 35.7% in the first group and 30% in the second group, and in the third group in 53.3%. The need for surfactant in the HIE group with RDS is 59.5%, and in the RDS group without HIE 84.2%. DIC associated with sepsis was found in 13.1-50% in those groups. In newborns with HIE and bradycardia, the probability of having RDS was on average 3.2 times higher than in those without bradycardia.
The application of the surfactant significantly improved the pH, pO2, pCO2, BE and chest X-ray in children with RDS. An Apgar score less than 6 at the fifth minute increases the risk of RDS by 3 times. The metabolic acidosis in the first 24 hours increases the risk of death by 23.6 times. The combination of HIE/ RDS significantly worsens the disease outcome. The use of scoring systems improved the early detection of high risk babies and initiation of early treatment increased the chances for survival without disabilities.
Multiplex PCR in Diagnosing Respiratory Tract Infections in Hospitalized Children
Authors: Popova Gorica , Jakjovska Tatjana , Arnaudova-Danevska Ivana , Boskovska Katerina , Spasovska Olga Smilevska 
Published: April 2024

Abstract

Objectives:
To elaborate the utility of multiplex quantitative polymerase chain reaction (multiplex qPCR) for the accurate diagnosis of severe respiratory tract infections (RTIs) in hospitalized children.

Methods:
In two separate periods during 2022, 76 respiratory specimens (combined throat/nasopharyngeal swabs) were submitted for multiplex qPCR regarding 26 respiratory pathogens. The specimens were obtained from children with severe RTIs hospitalized in the Institute for Respiratory Diseases in Children, Skopje.

Results:
Multiplex qPCR detected at least one respiratory pathogen in all examined specimens (76/76), with 83% (63/76) rate of co-infections. Considering that positive results are only the ones with Ct value below 28, the rates of detected pathogens and co-infections decrease to 75% and 22%, respectively. The most commonly detected pathogens during the spring period were Parainfluenza type 3 (PIV3) followed by Adenovirus (AdV) and Respiratory syncytial virus type B (RSVB) with frequency rate of 23%, 19% and 19%, respectively. During the autumn period, the most common were RSVB and Streptococcus pneumoniae with frequency rate of 31% and 17%, respectively.

Conclusion:
Multiplex qPCR is a powerful tool for diagnosing RTIs. Semi-quantification of the viral load by reporting Ct values added higher level of evidence for accurate diagnosis. Seasonal detection of the examined viruses was notable with higher prevalence of PIV3 in spring and RSVB in autumn period.
Enhancing Sustainable Practices in Screen-printing Businesses through Community Engagement: A Case Study of the Tegal Screen Printing Community
Authors: Mustofa Rochman Hadi , Narimo Sabar , Suranto  , Utama Refa Putra 
Published: April 2024

Objective: This study aims to describe the role of the Tegal T-shirt screen printing community (Tegal Screen Printing) in the t-shirt screen printing business in Tegal Regency, Indonesia, and to find out the obstacles faced by screen printing business actors and how to overcome them.

Theoretical Framework: Community of Practice (CoP) theory, Resource Dependency Theory, Social Learning Theory

Method: This study employs a qualitative case study methodology. The participants included Tegal Screen Printing's founders, community leaders, and community members. Included among the data collection methods are interviews, observations, and documentation. The validity of the data is carried out by triangulating the source and method. Data collection, reduction, display, and conclusion are the data analysis techniques used.

Results and Discussion: The study underscores the Community's importance in fostering business ethics and management skills while enhancing product quality. However, technical challenges like screen clogging and material scarcity persist, prompting the Community to offer support through technical assistance and guidance on financial reporting.

Research Implications: The research implications suggest that community platforms play a significant role in fostering business ethics, management skills, and product quality improvement. Additionally, addressing technical challenges and resource scarcity within communities can enhance overall support mechanisms for members. Furthermore, the findings highlight the importance of integrating practical assistance, such as technical support and financial guidance, into community initiatives to facilitate members' success in their endeavors.

Originality/Value: This research stands out for its focused exploration of the Tegal Screen Printing Community, shedding light on the distinct challenges and opportunities within this industry niche. By integrating business ethics with technical issues, it offers a comprehensive perspective rarely seen before. Moreover, its emphasis on practical solutions grounded in real experiences adds significant value. Through its empirical approach, this study contributes to a deeper understanding of how niche communities foster skill development and resource support among members, enhancing the broader discourse on community development within the screen printing industry.