bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effect of tonsillectomy and/or adenoidectomy on pulmonary arterial pressure in adults
Authors: Abdelwhab Saeed , Dessoukey Khaled. , Lotfy Gamal , Alsaeed Ashraf , Anwar Hesham 
Published: October 2008

Abstract
The aim of the study was to determine the mean pulmonary pressure in adult with hypertrophic tonsils and adenoids and to clarify whether tonsillectomy and adenoidectomy has any effect on mean pulmonary arterial pressure of these adult. The study was carried out on 50 patients with diagnosis of upper airway obstruction resulting from hypertrophied tonsils and adenoids (group1). 25 adults were assigned as control with similar age and sex distribution (group2). For study subjects Routine general Examinations, BMI, ECG, Chest X ray, Arterial blood gases and Echocardiography were done. Mean pulmonary arterial pressure was measured by using Doppler Echocardiography preoperatively and mean 3–4 months postoperatively in all subjects. Elevated PAP (pulmonary artery pressure) was found in 15 patients (30%) in group 1 preoperatively. Mean PAP was 28.34 ±5.11 mmHg preoperative in group 1 and 19.84 ± 5.0 mmHg in group 2 (p <0.001). PAP decrease to 22.38 ±4.28 mmHg postoperatively in group 1 (p <0.001). Arterial oxygen saturation (spo2%) increase from 93.5 ± 1.9% preoperatively to 95.3 ± 1.3% post operatively (p < 0.001). percent reduction of PAP postoperatively correlates to age (t=−2.3, p= 0.02), preoperative PAP (p =0.01) but no correlation was found with BMI. In conclusions, this Study showed that obstructed adenoid and hypertrophy of tonsils causes higher mean pulmonary artery pressure in adult & revealed that tonsil& adenoid is effective therapeutic measure in such patients. With early intervention is necessary to avoid progressive cardiopulmonary disease.
Radiographic evaluation of trigeminal neurovascular compression in patients with and without trigeminal neuralgia
Authors: Miller Jonathan P. , Acar Feridun , Hamilton Bronwyn E. , Burchiel Kim J. 
Published: October 2008

Object
Neurovascular compression (NVC) of the trigeminal nerve is associated with trigeminal neuralgia (TN), but also occurs in many patients without facial pain. This study is designed to identify anatomical characteristics of NVC associated with TN.

Methods
Thirty patients with Type 1 TN (intermittent shocklike pain) and 15 patients without facial pain underwent imaging for analysis of 30 trigeminal nerves ipsilateral to TN symptoms, 30 contralateral to TN symptoms, and 30 in asymptomatic patients. Patients underwent 3-T MR imaging including balanced fast-field echo and MR angiography. Images were fused and reconstructed into virtual cisternoscopy images that were evaluated to determine the presence and degree of NVC. Reconstructed coronal images were used to measure nerve diameter and crosssectional area.

Results
The incidence of arterial NVC in asymptomatic nerves, nerves contralateral to TN symptoms, and nerves ipsilateral to TN symptoms was 17%, 43%, and 57%, respectively. The difference between symptomatic and asymptomatic nerves was significant regarding the presence of NVC, nerve distortion, and the site of compression (p < 0.001, Fisher exact test). The most significant predictors of TN were compression of the proximal nerve (odds ratio 10.4) and nerve indentation or displacement (odds ratio 4.3). There was a tendency for the development of increasingly severe nerve compression with more advanced patient age across all groups. Decreased nerve size was observed in patients with TN but did not correlate with the presence or extent of NVC.

Conclusions
Trigeminal NVC occurs in asymptomatic patients but is more severe and more proximal in patients with TN. This information may help identify patients who are likely to benefit from microvascular decompression.
Completely endoscopic resection of intraparenchymal brain tumors
Authors: Kassam Amin B. , Engh Johnathan A. , Mintz Arlan H. , Prevedello Daniel M. 
Published: October 2008

Object
The authors introduce a novel technique of intraparenchymal brain tumor resection using a rod lens endoscope and parallel instrumentation via a transparent conduit.

Methods
Over a 4-year period, 21 patients underwent completely endoscopic removal of a subcortical brain lesion by means of a transparent conduit. Image guidance was used to direct the cannulation and resection of all lesions. Postoperative MR imaging or CT was performed to assess for residual tumor in all patients, and all patients were followed up postoperatively to assess for new neurological deficits or other surgical complications.

Results
The histopathological findings were as follows: 12 metastases, 5 glioblastomas, 3 cavernous malformations, and 1 hemangioblastoma. Total radiographically confirmed resection was achieved in 8 cases, near-total in 6 cases, and subtotal in 7 cases. There were no perioperative deaths. Complications included 1 infection and 1 pulmonary embolus. There were no postoperative hematomas, no postoperative seizures, and no worsened neurological deficits in the immediate postoperative period.

Conclusions
Fully endoscopic resection may be a technically feasible method of resection for selected subcortical masses. Further experience with this technique will help to determine its applicability and safety.
Clinical Presentation of Dengue in 150 Admitted Cases in Dhaka Medical College Hospital
Authors: Azad Md Abul Kalam , Mohammad Hanif , Alam Md Billal , Saha Anup Kumar , Ahmed Tofayel 
Published: October 2008

Dengue fever was not recognized as a major public health hazard in Bangladesh before 1999 outbreak, so there was little evidence and awareness in this regard. A prospective observational study was carried out to determine the risk group of patients suffering from dengue syndrome; clinical parameters of the subjects for hospitalization and the pattern of presentation of dengue fever in hospital care in different medicine units of Dhaka Medical College hospital from July 2000 to March 2001. Total 150 cases were selected randomly and diagnosed clinically as dengue, and were classified into 3 groups, i.e. 18 cases of classical dengue fever, 127 cases of dengue hemorrhagic fever (DHF-I and DHF-II) and 5 cases of dengue shock syndrome (DSS), and were discharged uneventfully. Among them 125(83.3%) were male and 25(16.7%) were female. Mean ages of the subjects were 26.75 Â±3.69, 27.59 Â± 1.18 and 10.67 Â± 2.33 years in respective groups. Mean temperature was 103.45Â±0.28, 103.08Â±0.13, and 104.00Â±1.00 Â°F with mean duration was 5.50Â±0.51 days, 6.12Â±0.2 days, and 5.00Â±1.15 in respective groups. Majority had profound weakness, headache, myalgia, anorexia, nausea, and vomiting. Diarrhoea, abdominal pain, organomegaly, ascites, and pleural effusion were frequent complaints in group-3 patients, whereas infrequent complaints in other groups. Haemorrhagic manifestations were common in group 2 and 3 patients, melaena being the most common manifestations. Â DOI = 10.3329/jom.v7i1.1355 J MEDICINE 2006; 7: 3-9
Groin Flap: A Good Converge for Hand Injury
Authors: Shamsuzzaman Md , Uddin SK Borhan , Masoom Md , Islam Md Anowarul , Haque Azizul 
Published: October 2008

Fifty cases of hand trauma of different aetiology with soft tissue loss with exposed tendons and bones were treated in NITOR and DMCH, Dhaka between January '97 and December '02 with groin flap. Eighty three percent (83%) cases have good results with excellent flap adhesion and no flap loss. Seventeen percent (17%) cases have some degree of flap loss which were taken to be acceptable. Overall result in terms of restoring the hand function was encouraging which was approximately eighty eight percent (88%). Â DOI = 10.3329/jom.v7i1.1357 J MEDICINE 2006; 7 : 15-19
Consciousness about Informed Consent amongst the Researcher in a Postgraduate Institute of Bangladesh
Authors: Shakoor MA , Ullah MD Ahsan , Rahman Md Shahidur , Saha Anup Kumar , Ar-Rashid Harun 
Published: October 2008

To assess the consciousness about informed consent (IC) of the researchers, a study was conducted in a postgraduate institute in Dhaka, Bangladesh from Dec' 2003 to Jan' 2004. A total of 39 researchers responded properly. All subjects were doctors who have completed a research work previously. A written questionnaire was given to the respondents to answer the questions about IC and then it was collected properly with the answer of the participants. The data was analyzed statistically. Most of the respondents 84.60% agreed that IC is a written consent and 94.90% respondents agreed that it includes risk and benefit. Maximum participants (97.40%) agreed that child's consent is not valid for a study, 89.70 % researchers agreed that confidentiality should be included in IC and 76.90% agreed that IC should include the duration of the study. 71.60% respondents agreed to give autonomy to the subject, 48.70% disagreed that the witness is necessary during taking IC, 66.70% respondents took IC from the study subjects during their study & 33.30 % had not taken any consent. From the present study, it can be concluded that most of the researchers of the concerned institute are knowledgeable about IC but many of them has no attitude to apply it in practice. As there is evidence of negligence to practice on IC during conducting research, awareness should be grown up amongst the researchers by conducting seminar, symposium and workshop to protect human rights during clinical trial. Â DOI = 10.3329/jom.v7i2.1363 J MEDICINE 2006; 7 : 46-50 Â
Human Rabies in Bangladesh â A Study of 684 Cases
Authors: Rahman M Matiur , Salimuzzaman M , Alam MD Billal , Rouf MA , Hossain M Jakir , Rahman M Ridwanur 
Published: October 2008

This descriptive study in the Infectious Disease Hospital, Dhaka, on rabies was carried out to see the patterns of presentation, age group at risk, state of vaccination following animal exposure and the interval between animal exposure and the development of the disease. Of 684 cases of rabies from June 1999 to November 2003, majority (64.18%) of the victims were within 15 years of age. Male gender (76.75%) and rural people (86.40%) constituted the bulk of the cases. 80.26% of cases had WHO category III exposure. Most of the cases were not vaccinated (86.04%). Among 93 cases who received vaccine, only 9.67% took tissue culture vaccine and 90.3% were treated with nerve tissue vaccine. None of the 684 cases were treated with RIG. Dog was the principal animal responsible for 95.76% cases. 65.93% of the cases developed the disease between 31 to 100 days after the animal exposure. DOI = 10.3329/jom.v8i1.1370 J MEDICINE 2007; 8 : 3-6 Â Â
Clinical Profile And Risk Association of DVT
Authors: Miah Md Titu , Hoque AKM Aminul , Rashid Md Harun Ur , Mahmood Tarek , Khan Raihan Rotap , Sarkar Shyamal 
Published: October 2008

This prospective study was conducted in Mymensingh Medical College Hospital over a period of one year among the diagnosed patients of DVT in medicine units to find out the disease association and risk factors. Mean age of the patients at the time of diagnosis was 37.8years with a standard deviation of 12.73 years with an even distribution. There was a mild female preponderance (M: F=2:3). 72.5% and 27.5% of the patients were admitted with unilateral and bilateral leg swelling respectively. No established risk factors was found about 30% of case OCP and malignancy account for highest number of association almost 22.5 % to each and other associated conditions were congestive cardiac failure (7.5%), post partum period (7.5%), renal impairment (7.5%) and prolonged immobilization (2.5%) . 92.5% patients enjoyed resolution while 7.5 patients died. Among three patients who died, two were male and one was female. However, thrombotic scan was not available and can not be offered to any patients. Almost all the findings of this study correlate well with other previous studies except age distribution for which further evaluation may be necessary. Â DOI = 10.3329/jom.v8i1.1372Â J MEDICINE 2007; 8 : 7-9
Jaundice in Pediatric Visceral Leishmaniasis (Kala-azar) Patients
Authors: Rashid AKM Mamunur , Mamun Abdulla Al , Rasul CH , Afrafuzzaman Md , Hossain Mukter , Rahman Md Mujibur 
Published: October 2008

Visceral leishmaniasis (Kala-azar) is endemic in many countries including Bangladesh. Clinical presentation of visceral leishmaniasis in children and adult may vary and at time may simulate many tropical and hepatobilliary diseases. Jaundice and ascites is not common in some patients. In this series of eleven cases Jaundice, splenomegaly, hepatomegaly and ascites are present in 55%, 100%, 91%, 27% of cases respectively. So, Kala-azar should be kept in mind while dealing with cases of many such clinical findings. Â DOI = 10.3329/jom.v8i1.1374 J MEDICINE 2007; 8 : 14-16
Rosai Dorfman Disease
Authors: Chowdhury Md Faizul Islam , Khandaker MA Kashem , Zaid Hossain M , Khatun Hazera , Hossain Md Murad , Karim Enamul 
Published: October 2008

Mr. Shahinoor an 18 year old male got himself admitted at DMCH in July,2007 with the complaints of bilateral neck swelling and fever for 1 month. The enlarged lymph nodes were clustered in cervical regions involving both anterior and posterior chains and largest one measuring 5 cmÃ2.5 cm.He was otherwise healthy on examination. Full blood count showed neutrophil leukocytosis and raised ESR.Sputum for AFB was found negative and xray chest was normal. FNA of lymph node showed non specific lymphadenitis with reactive hyperplasis. Lymph node biopsy was done and histopathology revealed Rosai Dorfman Disease, a very rare yet fascinating disorder also called Sinus Histiocytosis with Massive Lymphadenopathy.It is a benign proliferative disorder of the histiocytes. He was not given any tretament and is under follow up. Â DOI = 10.3329/jom.v8i1.1376 J MEDICINE 2007; 8 : 28-31
Views of the Students and Teachers about the New Curriculum (Curriculum 2002) and Their Opinion on in-Course Assessment System
Authors: Ahmed Abida , Begum Momotaj , Begum Shameema , Akhter Rezina , Rahman Nilufar , Khatun Ferpza 
Published: October 2008

Background: The academic activities of the 1st and 2nd year MBBS students are running according to the new curriculum (Curriculum 2002). Curriculum is a series of planned activities to which the learner may be exposed in order to achieve the learning goals. But due to ongoing modifications of society, disease demography, medical science, concepts of teaching and availability of newer technique; curriculum may need to be changed. Assessment is the process of testing a student's ability. A good assessment should be valid, reliable, practicable and objective. Without assessment the purpose of effective teaching will not fulfill. To change curricula, examination system or assessment system also needs to be changed. Though evaluation of students is an integral part of all educational processes, a suitable evaluation procedure is said to be lacking. So opinions of teachers as well as students are immensely important to develop an ideal evaluation procedure. Methodology: This cross-sectional prospective study was done in Dhaka Medical college over a period of 1 months.2nd year MBBS students( 100) and teachers of Physiology, Anatomy and Biochemistry (22) gave their opinion in this study in a mixed pattern of questionnaire ( both open-ended and closed) . Results: Majority of students( 84%) but minority of teachers opined that there was need of card completion examination as in course assessment system .Other teachers and students suggested for alternate examination instead of card completion examination like only MCQ (18%), both MCQ and SAQ (82%). Choice of venue of the examination were - tutorial class (58%), lecture class (21%), practical and tutorial class (21%). Discussion: Though present MBBS curriculum is a problem oriented scientific curriculum with modern concepts like MCQ, OSPE, SAQ and SOE; the teachers are facing a lot of problems in implementing the curriculum due to lack of orientation and shortage of manpower. Conclusion: In spite of criticisms Curriculum 2002 is a positive change in an academic field. In order to improve and update the curriculum; its planning should be constantly reviewed. Â DOI = 10.3329/jom.v8i2.1404 J MEDICINE 2007; 8 : 39-43
Cutaneous Manifestations of Systemic Lupus Erythematosus
Authors: Parveen Nahid , Das Dipak Kumar , Haque FRM Mahbubul , Haque Mahamudun Nabi Mohammad Momtazul 
Published: October 2008

Systemic lupus erythematosus (LE) is a heterogeneous, multisystem, autoimmune disease characterized by the production of auto-antibodies against several cell constituents. The skin is one of the target organs most variably affected by the disease can be yield valuable diagnostic & prognostic information. The present study was conducted to evaluate cutaneous manifestations of SLE in Bangladeshi patients. 100 cases of SLE were collected from the Department of Dermatology, BSMMU, Dhaka. The diagnosis was based on American Rheumatism Association Criteria. Cutaneous changes were recorded on a predevised pro forma. LE specific cutaneous changes noted were: Malar rash or butterfly rash (70.0%), maculopapular rash (19.0%), discoid rash (10.0%), and bullous LE (10.0%). Non specific LE lesions noted were: Photosensitivity (75.0%), alopecia (47.0%), oral mucosal lesion (34.0%), hyperpigmentation (20.0%), nail change (15.0%), Raynauds phenomenon (12.0%), Palmar erythema, genital lesion, periungual talangiectesia, leg ulcers, livedo reticularis, erythema multiform were rare. Systemic lupus erythematosus is a multisystem disease that predominantly affects women. Cutaneous lesions are the most important diagnostic tools as reflected by the fact that they account for four of the 11 revised American Rheumatism Association criteria of SLE. The pattern of skin changes may vary from place to place. Key Words: SLE, LE specific and non specific cutaneous lesions Â DOI = 10.3329/jom.v8i2.1405 J MEDICINE 2007; 8 : 44-48
Platelet Phaeresis for Component Therapy in Dhaka Medical College- A Study of 26 Procedures
Authors: Banu Laila Arjumand , Hossain Kazi Nowshad 
Published: October 2008

Platelet separation by aphaeresis machine from single donor was started in Blood Transfusion Department of Dhaka Medical College Hospital, from 10th April 2002. This study includes 26 procedures done in this dept. from the period of 10th April 2002 to 4th June 2003. Observation showed that demand of platelet came from different wards for different types of diseases such as , for Dengue- 8 cases, for Aplastic anaemia-2 cases, for Ovarian tumour-2 cases, for Caesarian section post operative DIC -2 cases, for AML with low platelet count -3 cases, for IUD with low platelet count -1 case, for Blood cancer -1 case , for NHL chemotherapy induced thrombocytopenia- 1 case , for Dengue Shock Syndrome - 1 case , 5 units donated in Shishu Hospital . Platelet was supplied according to group specific of the patient. Such as, 12 cases were O +ve, 10 cases were B +ve ,3 cases were A+ve and 1 case was AB+ve. Â Â Â Â DOI = 10.3329/jom.v8i2.1407 J MEDICINE 2007; 8 : 53-56
Plasma Fibrinogen Level, Platelet Aggregation and Platelet Count in Stable Angina
Authors: Begum Momotaj , Hai Ma , Chowdhury ASM Lokman Hossain , Begum Noorjahan 
Published: October 2008

This was a prospective study. The study was done from July 1997 to June 98. All the cases were selected from the outdoor patients of National Institute of Cardiovascular Diseases (NICVD), Controls were selected from healthy volunteers. The plasma fibrinogen level, platelet aggregation and platelet count were studied on a total number of 35 subjects with age ranged from 40-60 years of both sexes. Of these 20 were normal healthy subjects and 15 were patients with stable angina. Plasma fibrinogen level were normal as like as healthy subjects. Platelet aggreagations were increased in some cases but others show normal findings. The platelet count were slightly decreased but it was within normal range. Form this study it may be observed that normal plasma fibrinogen level and increased platelet aggregation with normal platelet count may occur in patients with stable angina. The increased platelet aggregation indicate hypercoagulable states which may aggravate the condition of patients with stable angina and this is the risk factor for the further development of severe ischemia of the heart. So, the routine investigation of plasma fibrinogen level, platelet aggregation and platelet count may be helpful to utilize them as background information both for therapeutic and preventive measures in patients with stable angina. Â Â Â DOI = 10.3329/jom.v8i2.1408 J MEDICINE 2007; 8 : 57-59
A Comparative Treatment Results of Oesophageal Squamous Cell Carcinoma by Neoadjuvant Chemotherapy followed by Radiotherapy versus Radiotherapy Alone
Authors: Salam B , Perveen I , Faruque GM , Mohammed AKMG 
Published: October 2008

Background: Studies suggest that neoadjuvant chemotherapy prior to radiotherapy results in improved response and survival in large primary lesion. This study aimed to evaluate the role of neoadjuvant chemotherapy prior to radiotherapy in patients with localized oesophageal cancer. Method: In this randomized controlled study 60 selected cases of oesophageal squamous cell carcinoma were randomized to Arm-A & Arm-B. Patients assigned to combination therapies(Arm- A) received two cycles (4 weekly) of injectable 5- fluorouracil(400mg/m2/day for five days ) and mitomicin C (7mg/ m2 on D1) as neoadjuvant chemotherapy prior to radiotherapy(44GY in 22 fractions). Patients of Arm-B received radiotherapy alone as in arm-A. Treatment responses were compared following completion of treatment at six and 12 weeks. Complete response was defined as no difficulty in swallowing and no visible growth in follow-up barium swallow X-Ray. Partial response was defined as difficulty in swallowing semisolids but not liquids and persistence of residual growth in barium swallow X-Ray. Results: The study initially enrolled 68 patients but eight patients dropped out. Complete response occurred in 66.6% (20) patients who received combination therapies (n=30), where as in 40% (12) patients who received radiotherapy alone (P= < 0.05). Partial response occurred in 33.33% patients assigned to have pre-irradiation chemotherapy and in 60% patients having radiotherapy alone. Toxicities like dysphagia, anorexia, vomiting was more in combination therapy group, but it was acceptable. Conclusion: Neoadjuvant chemotherapy followed by radiation therapy demonstrated better response than radiation alone at the expense of toxicity in patients with localized oesophageal cancer. Â DOI = 10.3329/jom.v8i2.1409 J MEDICINE 2007; 8 : 60-63
Review on Efficacy of Lumber Traction on Low Back Pain
Authors: Rahman Md Shahidur , Uddin Mohd Taslim , Ahsanulla Md 
Published: October 2008

Back pain is a problem to health professionals and to the society. Low back pain is now one of the most common reasons for work loss, health care use and sickness benefit. There are many causes of low back pain. Non-specific mechanical low back pain is most common. Treatment options include surgical and conservative. Conservative treatment is usually given with analgesics, thermo therapy and lumber traction. Treatment plan and referral is made on the basis of judgment on clinical findings. The aim of the present review was to assess the efficacy of traction for LBP patients with or without radiating pain. To reflect clinical practice, we need to understand the clinical parameters and treatment regimes being used by clinicians, and these must be addressed before a trial can be designed to look further at the effectiveness of traction for LBP with or without radiating pain. The evidence for the use of traction in LBP remains inconclusive because of the continued lack of methodological rigor and the limited application of clinical parameters as used in clinical practice. Keywords: Low back pain, Lumber traction, Efficacy. Â Â Â DOI = 10.3329/jom.v8i2.1412 J MEDICINE 2007; 8 : 69-73