bluuebunny/crossref_metadata_2025_split huggingface dataset:
ChemInform Abstract: Scaffold Topologies. Part 1. Exhaustive Enumeration up to Eight Rings.
Authors: Pollock Sara N. , Coutsias Evangelos A. , Wester Michael J. , Oprea Tudor I. 
Published: September 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Mold2, Molecular Descriptors from 2D Structures for Chemoinformatics and Toxicoinformatics.
Authors: Hong Huixiao , Xie Qian , Ge Weigong , Qian Feng , Fang Hong , Shi Leming , Su Zhenqiang , Perkins Roger , Tong Weida 
Published: September 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Design and Exploration of Target‐Selective Chemical Space Representations.
Authors: Vogt Ingo , Bajorath Juergen 
Published: September 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Hot‐Spots‐Guided Receptor‐Based Pharmacophores (HS‐Pharm): A Knowledge‐Based Approach to Identify Ligand‐Anchoring Atoms in Protein Cavities and Prioritize Structure‐Based Pharmacophores.
Authors: Barillari Caterina , Marcou Gilles , Rognan Didier 
Published: September 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: An Improved PMF Scoring Function for Universally Predicting the Interactions of a Ligand with Protein, DNA, and RNA.
Authors: Li Honglin , et al. et al. 
Published: September 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Advances in Polynuclear Iron(II), Iron(III) and Cobalt(II) Spin‐Crossover Compounds
Authors: Murray Keith S. 
Published: September 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Hydride Encapsulation by Molecular Alkali‐Metal Clusters
Authors: Haywood Joanna , Wheatley Andrew E. H. 
Published: September 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Transition Metal Catalyzed Synthesis of Organosulfur Compounds
Authors: Arisawa Mieko , Yamaguchi Masahiko 
Published: September 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: New Methods in Asymmetric Catalysis Based on New Hemi‐Labile Bidentate Ligands
Authors: Charette Andre B. , Cote Alexandre , Desrosiers Jean‐Nicolas , Bonnaventure Isabelle , Lindsay Vincent N. G. , Lauzon Caroline , Tannous Jad , Boezio Alessandro A. 
Published: September 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: 2‐Heteroatom‐Substituted Alkanoic Acids
Authors: Chemler S. R. , Zabawa T. P. 
Published: September 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Interstrand DNA Cross‐Links Induced by α,β‐Unsaturated Aldehydes Derived from Lipid Peroxidation and Environmental Sources
Authors: Stone Michael P. , et al. et al. 
Published: September 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Metabolic Engineering of Microorganisms for Isoprenoid Production
Authors: Kirby James , Keasling Jay D. 
Published: September 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Chemical Tools for Functional Studies of Glycans
Authors: Park Sungjin , Lee Myung‐Ryul , Shin Injae 
Published: September 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Effect of Overdischarge on Swelling and Recharge Performance of Lithium Ion Cells
Authors: LI Hui‐Fang , GAO Jun‐Kui , ZHANG Shao‐Li 
Published: September 2008

AbstractEffects of overdischarge on characteristics of lithium ion cells were deeply studied, and experiments have been made to reveal its mechanisms. The results suggest that overdischarge may result in large swelling of cells and degradation of recharge capabilities. The mechanism can be explained as that: a copper foil used as an anode collector will be oxidized to copper ion when deep overdischarge occurs and reduce at the anode in recharging progress, which greatly deteriorates the cell efficiency; solid electrolyte interface (SEI) film is to decompose and reform because of excessive de‐intercalation of lithium ions, and the released gas such as carbon dioxide makes the cell bulge. The experimental results prove that when 20% Li(Ni1/3Co1/3Mn1/3)O2 was added to LiCoO2 cathode materials, the cell swelling rate could be greatly reduced, and the recharge capability would be enhanced much.
Immobilized Palladium on Organic‐inorganic Hybrid Materials: A Novel and Reusable Catalyst for the Copper‐Free Sonogashira Coupling Reaction
Authors: ZHANG Li‐Yuan , WANG Lei 
Published: September 2008

AbstractThe immobilized palladium on organic‐inorganic hybrid materials catalyzing the copper‐free Sonogashira coupling reaction has been described. Terminal alkynes were reacted with aryl iodides and aryl bromides in the presence of 3‐[N,N‐bis(diphenylphosphino)amino]propyl functionalized silica gel immobilized palladium catalyst. The protocol involved the use of ethylene glycol as a solvent, and triethylamine as a base. The reactions generated the corresponding cross‐coupling products in excellent yields. Furthermore, the silica‐supported phosphine palladium complexes and ethylene glycol could be recovered and recycled for six consecutive trials without significant loss of their activity.
Hydrothermal Synthesis, Crystal Structures and Photoluminescence of Two Novel Metal‐organic Supramolecular Frameworks Based on Mixed Ligands of Dipyrazino[2,3‐f:2′,3′‐h]quinoxaline and Pyridine‐2,5‐dicarboxylic Acid
Authors: WANG Xiu‐Li , LIU Guo‐Cheng , LIN Hong‐Yan , CHEN Bao‐Kuan , FANG Jia‐Ni , ZHAO Hai‐Yan 
Published: September 2008

AbstractTwo novel metal‐organic frameworks [Zn2(Dpq)2(2,5‐pda)2(H2O)2]·2H2O (1) (dipyrazino[2,3‐f:2′3′‐h]quinoxaline=Dpq) and [Cd2(Dpq)2(2,5‐pda)2]·2H2O (2) (pyridine‐2,5‐dicarboxylic acid=2,5‐H2pda) have been obtained from hydrothermal reactions of two different metal(II) nitrates with the same mixed ligands Dpq and 2,5‐H2pda, and structurally characterized by elemental analyses, TG, IR spectroscopy, and single‐crystal X‐ray diffraction analyse. Single‐crystal X‐ray analyses show that the metal ions are bridged by different coordination modes of 2,5‐pda to form a dimer in 1, 2D rhombic grid in 2, respectively. In the compound 1, adjacent dimers are packed through hydrogen bonds and ‐ aromatic stacking interactions to form a distorted α‐Po supramolecular structure. In the compound 2, adjacent polymer layers are further linked by hydrogen bonds to form a distorted α‐Po 3D supramolecular framework stabilized by ‐ stacking interactions. The different structures of compounds 1 and 2 illustrate the influence of the metal ions and ligands on the self‐assembly of polymeric coordination architectures. In addition, the title compounds exhibit blue emission in the solid state at room temperature.
Second‐order Scattering and Frequency Doubling Scattering Spectra of Thallium(III)‐Methotrexate System and Its Analytical Application
Authors: XI Cun‐Xian , LIU Zhong‐Fang , HU Xiao‐Li , LIU Shao‐Pu , DUAN Hui 
Published: September 2008

AbstractIn pH 4.9 Britton‐Robinson buffer solution, methotrexate (MTX) reacted with thallium(III) to form a 3:1 chelate. This resulted in great enhancement of second‐order scattering (SOS) spectra and frequency doubling scattering (FDS) spectra and appearance of new SOS and FDS spectra. Their maximum wavelengths were located at 520 and 390 nm, respectively. The increments of scattering intensities (ΔI) were directly proportional to the concentrations of MTX in the ranges of 0.022–2.0 µg·mL−1(SOS method) and 0.008–2.5 µg·mL−1(FDS method). The methods exhibited high sensitivities. The detection limits for MTX were 7.4 ng·mL−1(SOS method) and 2.3 ng·mL−1(FDS method), respectively. The optimum conditions of the reaction, the influencing factors and the effects of coexisting substances were investigated. A highly sensitive, simple and fast method for the determination of MTX has been developed. The method can be applied satisfactorily to the determination of MTX in human serum samples. In this work, the charge distribution of MTX was calculated by a CNDO quantum chemistry method. In addition, the reaction mechanism was discussed.
An HPLC Method for Determination of a New Diorganotin(IV) Benzohydroxamate in Rat Plasma and Its Application to Pharmacokinetic Studies
Authors: LI Yun‐Lan , LI Yong , LIU Jin‐Jie , YANG Li , NIU Xiao‐Qiang , LI Qing‐Shan 
Published: September 2008

Abstract[(n‐Bu)2Sn{4‐ClC6H4C(O)NHO}2] (DBDCT) is a new diorganotin(IV) benzohydroxamate which shows high in vivo antitumor activity with relative low toxicity. An HPLC method for the determination of diorganotin(IV) benzohydroxamate (DBDCT) was first validated in the pharmacokinetic studies in plasma. The rat plasma was deproteinized with methanol that contained acetanilide as the internal standard and then separated. The HPLC assay was carried out using a Diamonsil ODS (4.6 mm×200 mm, 5 µm) column. The mobile phase was methanol and 0.5% trifluoroacetic acid (TFA) in water (30:70, V/V, pH 3.0) with a flow rate of 1.0 mL·min−1. The detection wavelength was set at 238 nm. This method was found to be linear within the concentration range of 0.1–25 ��g·mL−1 (r=0.9992). The limit values of quantification and detection were 50 and 10 ng·mL−1, respectively. The method was used to determine the concentration‐time profiles for DBDCT in the plasma after single intravenous administration with different doses to rats (2, 5, 12 mg·kg−1). The pharmacokinetics parameter calculations and modeling were carried out using the 3p97 pharmacokinetics software. The results showed that the concentration‐time curve of DBDCT in rat plasma could be fitted to the two‐component model.
An Unprecedented 2D 4f‐3d‐5d Multimetal‐Isonicotinic Acid Complex: Synthesis, Structural Characterization and Magnetic Properties
Authors: CHEN Wen‐Tong , ZENG Xi‐Rui , LIU Dong‐Sheng , YING Shao‐Ming , LIU Jiu‐Hui 
Published: September 2008

AbstractA novel heterometallic metal‐isonicotinic acid inorganic‐organic hybrid complex [Zn0.5(H2O)]{(Hg2Cl5)‐ [Er(C6NO2H4)3(H2O)2]}(HgCl2)·0.5CH3OH·0.5H2O (1) has been successfully synthesized via a hydrothermal reaction and structurally characterized by single‐crystal X‐ray diffraction. Complex 1 crystallizes in the space group C2/c of the monoclinic system with eight formula units in a cell: a=34.165(4) Å, b=9.4692(8) Å, c=24.575(3) Å, β =115.090(5)°, V=7200(1) Å3, C18.50H21Cl7ErHg3N3O10Zn0.50, Mr=1495.25, Dc=2.759 g/cm3, T=293(2) K, µ(Mo Kα) =15.954 mm−1, F(000) =5400 and R1/wR2=0.0561/0.0909 for 3157 observed reflections [I>2δ(I)] and 6468 unique reflections. Complex 1 is characteristic of a novel 2D {(Hg2Cl5)[Er(C6NO2H4)3(H2O)2]} layered structure constructed from the [Er(C6NO2H4)3(H2O)2] chains interconnected by the Hg2Cl5− linkers. The 2D {(Hg2Cl5)[Er(C6NO2H4)3(H2O)2]} layers, mercury chloride and the lattice water molecules are held together via hydrogen bonds to form a three‐dimensional framework with the methanol molecules and the hydrated zinc ions located in the cavities. The magnetic properties show that complex 1 exhibits antiferromagnetic‐like interactions.
Self‐condensation of Terminal Acetylenic Ketones via Organozinc Species
Authors: GAO Jun‐Li , LIU Yong‐Kang , XUE Song 
Published: September 2008

AbstractA self‐condensation reaction of α,β‐acetylenic ketones via organozinc species CF3CO2ZnEt to afford the β‐branched Morita‐Bayllis‐Hillman adducts has been developed. This reaction system provides functionalized trisubstituted olefins in good yields. Organozinc species CF3CO2ZnCH2I, an efficient cyclopropanation reagent, can also react with aromatic acetylenic ketones to provide 2,5‐dihydrofurans in moderate yields.
Synthesis of SiH Functional Poly(phenylsilane) and Organosilane Copolymers: Low‐valent Titanium Induced Polymerization of Organodichlorosilanes
Authors: LI Zhi‐Fang , HUANG Jia‐Bang , LAI Guo‐Qiao , JIANG Jian‐Xiong , ZHANG Yong‐Min 
Published: September 2008

AbstractUsing the low‐valent titanium reagent (Zn/TiCl4), dichlorophenylsilane underwent a reductive polymerization reaction to give Si–H functional poly(phenylsilane) (Mw/Mn=2.5, Mn=2400) in a moderate yield. Applying this method, the corresponding organosilane copolymers (2b–2f) were also obtained. The absorption maxima of these organosilane copolymers are remarkably hypsochromically shifted in comparison with those of poly(diarylsilane)s.
Preparation of Silyl Ethers Using Hexamethyldisilazane in the Presence of N‐Bromosuccinimide under Mild and Solvent‐Free Conditions
Authors: SHATERIAN Hamid Reza , DOOSTMOHAMMADI Razieh , GHASHANG Majid 
Published: September 2008

AbstractA mild, simple, novel and highly efficient method for the rapid protection of various primary, secondary, tertiary aliphatic and aromatic alcohols using hexamethyldisilazane (HMDS) in the presence of N‐bromosuccinimide (NBS) as an active, inexpensive, non‐toxic and readily available catalyst under solvent‐free conditions is described. Trimethylsilyl ethers were prepared in high to excellent yields with short reaction time under mild and almost neutral reaction conditions.
Synthesis of 2′,3′‐Di‐O‐acetylfrangulin A and Prinoidin, Two Novel Anthracene L‐Rhamnopyranosides Isolated from Rhamnus nepalensis
Authors: SONG Gao‐Peng , WANG Peng , ZHANG Zai‐Hong , SHI Da‐Kuo , LI Ying‐Xia 
Published: September 2008

AbstractThe total synthesis of 2′,3′‐di‐O‐acetylfrangulin A (1) and prinoidin (2), which were isolated from Rhamnus nepalensis and showed significant cytotoxicity to KB cell line, was achieved for the first time. The structures of the two compounds were confirmed by 1H NMR, 13C NMR, 1H‐1H COSY, HMQC and HMBC.
Synthesis, Crystal Structure and Electrochemical Studies of catena‐Poly([bis(1‐vinyl‐1H‐imidazole‐κN3)copper(II)]‐ µ ‐phthalato‐κ2O:O′)
Authors: LI Shao‐Xiang , ZHAO Guang‐Fa , LIU Fa‐Qian , HUANG Zhao‐Ge , LI Wei‐Hua , LIU Guang‐Ye 
Published: September 2008

AbstractThe crystal of [Cu(pa)(vim)2]n (where pa=phthalic acid dianion, vim=1‐vinyl‐1H‐imidazole) was synthesized and its structure was characterized by X‐ray single crystal diffractometry and elemental analysis. It crystallizes in monoclinic system, C2/c space group with the cell parameters of a=1.6527(3) nm, b=0.81800(16) nm, c=1.4463(3) nm, β=113.19(3)°, V=1.7973(7) nm3, Z=4, and Dc=1.537 g·cm−3. Final R indices [I>2δ(I)] are: R1=0.0476, wR2=0.1235 while R indices for all data are: R1=0.0693, wR2=0.1355. The title compound exhibits an existence of polymeric zigzag chains extended along c‐axis. Each Cu(II) ion is located at a crystallographic center of symmetry being coordinated by two N and two O atoms in a distorted square‐planar geometry. The electrochemical studies reveal that redox of Cu2+/Cu+ is a quasi‐reversible one‐electron process.
Electrochemical Reduction and Carboxylation of Ethyl Cinnamate in MeCN
Authors: WANG Huan , DU Yan‐Fang , LIN Mei‐Yu , ZHANG Kai , LU Jia‐Xing 
Published: September 2008

AbstractThe electrochemical reduction and carboxylation of ethyl cinnamate have been carried out in an undivided cell equipped with a Mg sacrificial anode using MeCN as solvent. Direct electroreduction led to the formation of the hydrodimers and saturated ester. And electrocarboxylation was carried out in the presence of CO2. The global yield and the ratio of mono‐ to dicarboxylic acids were strongly affected by various factors: electrode material, electrolysis potential, the substrate concentration and temperature. The high yield (78%) was obtained under an optimized reaction condition (cathode: Ni; electrolysis potential: −1.7 V; substrate concentration: 0.1 mol·L−1; and temperature: −10 °C).
Substantial family history of prostate cancer in black men recruited for prostate cancer screening
Authors: Mastalski Kathleen , Coups Elliot J. , Ruth Karen , Raysor Susan , Giri Veda N. 
Published: September 2008

AbstractBACKGROUND.Black men are at increased risk for prostate cancer (PCA), particularly with a family history (FH) of the disease. Previous reports have raised concern for suboptimal screening of black men with an FH of PCA. The extent of FH of PCA are reported from a prospective, longitudinal PCA screening program for high‐risk men.METHODS.Black men ages 35 to 69 years are eligible for PCA screening through the Prostate Cancer Risk Assessment Program (PRAP) regardless of FH. Rates of self‐reported FH of PCA, breast, and colon cancer at baseline were compared with an age‐matched sample of black men from the 2005 National Health Interview Survey (NHIS) using standard statistical methods.RESULTS.As of January 2007, 332 black men with pedigree information were enrolled in PRAP and FH of PCA was compared with 838 black men from the 2005 NHIS. Black men in PRAP reported significantly more first‐degree relatives with PCA compared with black men in the 2005 NHIS (34.3% [95% confidence interval (95% CI), 29.2‐39.7] vs 5.7% [95% CI, 3.9‐7.4]). Black men in PRAP also had more FH of breast cancer compared with those in the 2005 NHIS (11.5% [95% CI, 8.2‐15.4] vs 6.3% [95% CI, 4.6‐8.0]).CONCLUSIONS.FH of PCA appears to be a motivating factor for black men seeking PCA screening. Targeted recruitment and education among black families should improve PCA screening rates. Efforts to recruit black men without an FH of PCA are also needed. Cancer 2008. © 2008 American Cancer Society.
Cryoablation or radiofrequency ablation of the small renal mass
Authors: Kunkle David A. , Uzzo Robert G. 
Published: September 2008

AbstractBACKGROUND.The incidence of renal cell carcinoma is rising because of incidental detection of small renal masses (SRMs). Although surgical resection remains the standard of care, cryoablation and radiofrequency ablation (RFA) have emerged as minimally invasive treatment alternatives. The authors of this report performed a comparative meta‐analysis evaluating cryoablation and RFA as primary treatment for SRMs.METHODS.A search of the MEDLINE database was performed reviewing the world literature for clinically localized renal masses treated by cryoablation or RFA.RESULTS.Forty‐seven studies representing 1375 kidney lesions treated by cryoablation or RFA were analyzed. No differences were detected between ablation modalities with regard to mean patient age (P = .17), tumor size (P = .12), or duration of follow‐up (P = .53). Pretreatment biopsy was performed more often for cryoablated lesions (82.3%) than for RFA (62.2%; P < .0001). Unknown pathology occurred at a significantly higher rate for SRMs that underwent RFA (40.4%) versus cryoablation (24.5%; P < .0001). Repeat ablation was performed more often after RFA (8.5% vs 1.3%; P < .0001), and the rates of local tumor progression were significantly higher for RFA (12.9% vs 5.2%; P < .0001) compared with cryoablation. The higher incidence of local tumor progression was found to be correlated significantly with treatment by RFA on univariate analysis (P = .001) and on multivariate regression analysis (P = .003). Metastasis was reported less frequently for cryoablation (1.0%) versus RFA (2.5%; P = .06). Cryoablation usually was performed laparoscopically (65%), whereas 94% of lesions that were treated with RFA were approached percutaneously.CONCLUSIONS.Ablation of SRMs is a viable strategy based on short‐term oncologic outcomes. Although extended oncologic efficacy remains to be established for ablation modalities, the current data suggest that cryoablation results in fewer retreatments and improved local tumor control, and it may be associated with a lower risk of metastatic progression compared with RFA. Cancer 2008. © 2008 American Cancer Society.
CO Blocking of D2 Dissociative Adsorption on Ru(0001)
Authors: Ueta Hirokazu , Groot Irene M. N. , Gleeson Michael A. , Stolte Steven , McBane George C. , Juurlink Ludo B. F. , Kleyn Aart W. 
Published: September 2008

AbstractThe influence of pre‐adsorbed CO on the dissociative adsorption of D2 on Ru(0001) is studied by molecular‐beam techniques. We determine the initial dissociation probability of D2 as a function of its kinetic energy for various CO pre‐coverages between 0.00 and 0.67 monolayers (ML) at a surface temperature of 180 K. The results indicate that CO blocks D2 dissociation and perturbs the local surface reactivity up to the nearest‐neighbour Ru atoms. Non‐activated sticking and dissociation become less important with increasing CO coverage, and vanish at θCO≈0.33 ML. In addition, at high D2 kinetic energy (>35 kJ mol−1) the site‐blocking capability of CO decreases rapidly. These observations are attributed to a CO‐induced activation barrier for D2 dissociation in the vicinity of CO molecules.