bluuebunny/crossref_metadata_2025_split huggingface dataset:
Excretion pattern of branched‐chain amino acid metabolites during the course of acute infections in a patient with methylmalonic acidaemia
Authors: KØlvraa S. , Gregersen N. , Christensen E. , Rasmussen K. 
Published: February 2006

AbstractA 1‐year‐old boy with a typical B12‐responsive form of methylmalonic acidaemia was hospitalized twice due to acute bacterial infections. On both occasions, the child was lethargic with a severe ketoacidosis on admission. Intensive therapy with protein restriction, intravenous administration of electrolytes and antibiotics was effective within 4 days on both occasions. The urinary excretion of organic acids showed the same pattern on both occasions. There were rising excretion concentrations, reaching a peak value within the first 24‐hour period, for the following compounds: 3‐hydroxybutyric acid, 3‐hydroxypropionic acid, 3‐hydroxyisobutyric acid and 3‐hydroxyisovaleric acid. Excretion concentrations of the following rose for 48 h: isobutyric acid, 2‐methylbutyric acid, isovaleric acid, lactic acid and the 2‐oxo‐acids.There was no increase until 12–24 h after the onset of severe illness in the excretion of propionic acid and methylmalonic acid. Propionic acid excretion was maximal at about 48 h, while peak excretion of methylmalonic acid was delayed until about 72 h after the onset of severe illness; at this time there was clinical improvement. The biochemical implications of this excretion pattern are discussed.
Defective adenosylcobalamin synthesis in a case of transcobalamin II deficiency
Authors: Linnell J. C. , Quadros E. V. , Elliott P. G. , Malleson P. 
Published: February 2006

AbstractCobalamin metabolism has been investigated in a new case of transcobalamin II (TC II) deficiency. Using the chromatobioautographic technique, an abnormal distribution of cobalamins was detected in the child's erythrocytes and reduced synthesis of adenosylcobalamin but not of methylcobalamin in cultured fibroblasts. These results suggest that there may be a close link between TC II‐mediated cobalamin transport and intracellular synthesis of adenosylcobalamin (Ado‐Cbl).
Variation of urinary excretion of aspartylglucosamine and associated clinical findings in aspartylglucosaminuria
Authors: Aula P. , Raivio K. O. , Maury P. 
Published: February 2006

AbstractThe urinary excretion of aspartylglucosamine (AADG), the main accumulating glycoprotein degradation product in aspartylglucosaminuria (AGU), was studied in 40 patients at various stages of the disease. Only slight variation was found when the amount of AADG excreted by ten AGU patients under 10 years of age was compared with AADG excretion of older patients at a clinically advanced stage of the disease. The 24 h AADG excretion of the younger patients was 354 mg compared with 441 mg in the group often patients over 20 years of age. Clinical symptoms were unrelated to AADG excretion.
A formal approach to property testing in causally consistent distributed traces
Authors: Hallal H. H. , Boroday S. , Petrenko A. , Ulrich A. 
Published: February 2006

Abstract
A formal framework for the analysis of execution traces collected from distributed systems at run-time is presented. We introduce the notions of event and message traces to capture the consistency of causal dependencies between the elements of a trace. We formulate an approach to property testing where a partially ordered execution trace is modeled by a collection of communicating automata. We prove that the model exactly characterizes the causality relation between the events/messages in the observed trace and discuss the implementation of this approach in SDL, where ObjectGEODE is used to verify properties using model-checking techniques. Finally, we illustrate the approach with industrial case studies.
Sensitivity and Utility of Parathyroid Scintigraphy in Patients with Primary Versus Secondary and Tertiary Hyperparathyroidism
Authors: Pham Tuan H. , Sterioff Sylvester , Mullan Brian P. , Wiseman Gregory A. , Sebo Thomas J. , Grant Clive S. 
Published: February 2006

AbstractIntroductionParathyroid scintigraphy (PS) may be used to localize hyperactive parathyroid glands preoperatively. Performance of PS in the setting of secondary and tertiary hyperparathyroidism (HPT) is not well quantified. The performance of PS in secondary/tertiary HPT versus primary HPT may reflect physiologic as well as radiopharmaceutical kinetic differences between multigland hyperplasia versus adenoma. The aim of this study was to review the performance of PS in secondary/tertiary HPT with a comparison to that for primary HPT. Moreover, we evaluated (1) the sensitivity of PS in detecting enlarged glands, and (2) PS detectability as a function of gland weight.MethodsWe performed a retrospective review of the Mayo Clinic database from 2000 to 2004. We identified 40 patients with secondary or tertiary HPT as well as a matched control group of 40 patients with primary HPT who had had preoperative PS and underwent parathyroid surgery.ResultsParathyroid scintigraphy correctly localized all enlarged glands in 88% of patients in the primary HPT group. PS correctly identified both the number and locations of all hyperplastic glands in only 28% of the secondary/tertiary HPT patients. PS failed to identify one enlarged gland in 23% of the patients and two or more enlarged glands in 40% of the patients. PS correctly detects the largest gland in 88% of the patients with secondary and tertiary HPT. The mean gland weight detectable by PS was 612 ± 120 mg for primary HPT. In secondary/tertiary HPT, glands detected by PS had a mean weight of 950 ± 109 mg, whereas the mean weight was 276 ± 34 mg for undetected glands (P < 0.002).ConclusionsParathyroid scintigraphy is a sensitive study for localizing parathyroid glands preoperatively in primary HPT patients. Its sensitivity is low in secondary and tertiary HPT patients. Thus PS has limited value as a preoperative localization study in secondary/tertiary HPT patients.
Structural study of TiO2 thin films by micro-Raman spectroscopy
Authors: Niilisk Ahti , Moppel Mart , Pärs Martti , Sildos Ilmo , Jantson Taavi , Avarmaa Tea , Jaaniso Raivo , Aarik Jaan 
Published: February 2006

Abstract
The Raman spectroscopy method was used for structural characterization of TiO2 thin films prepared by atomic layer deposition (ALD) and pulsed laser deposition (PLD) on fused silica and single-crystal silicon and sapphire substrates. Using ALD, anatase thin films were grown on silica and silicon substrates at temperatures 125–425 °C. At higher deposition temperatures, mixed anatase and rutile phases grew on these substrates. Post-growth annealing resulted in anatase-to-rutile phase transitions at 750 °C in the case of pure anatase films. The films that contained chlorine residues and were amorphous in their as-grown stage transformed into anatase phase at 400 °C and retained this phase even after annealing at 900 °C. On single crystal sapphire substrates, phase-pure rutile films were obtained by ALD at 425 °C and higher temperatures without additional annealing. Thin films that predominantly contained brookite phase were grown by PLD on silica substrates using rutile as a starting material.
Local Knowledge, Dynamism and the Politics of Struggle: A Case Study of the Hmong in Northern Thailand
Authors: Siriphon Aranya 
Published: February 2006

The Hmong are not passive actors who wait for help from development workers and other authorities. Instead, they actively engage themselves within a process of social negotiation between unequal socio-economic and political groups, a ‘dynamic knowledge system’. Three case studies from a Hmong Thantam community are used to better understand the process of social negotiation with multiple actors within complex power relations. More importantly, their dynamic local knowledge is used as a strategy to struggle against, and reconcile with, more powerful forces; the result of this process is the ‘complexity’ which happens as a response to powerIt's possible to find knowledge from any place in the world when we humans learn from one another. Throughout the generations we Hmong have learned from many diverse sources. In order to fulfil our lives, we young Hmong still learn from the whole world. Laoyeng Saehang, A headman of Thantam village, Northern Thailand, 1998.
Musk deer farming in China
Authors: Xiuxiang Meng , Caiquan Zhou , Jinchu Hu , Cao Li , Zhibin Meng , Jinchao Feng , Yijun Zhou , Yinjiu Zhu 
Published: February 2006

AbstractFive musk deer species (genus Moschus) are distributed in China, and the present estimated numbers in the wild are between 220 000 and 320 000. Population size of musk deer has dropped significantly due to historical over-hunting and loss or degradation of their habitat. Musk deer farming, therefore, has become one of the most appropriate ways to protect and utilize musk deer resources. In China, musk deer farming and extracting musk from the captive musk deer have been reasonably successful since the early 1950s. At present three species of musk deer, namely forest (Moschus Berezovskii), alpine (M. sifanicus) and Siberian (M. moschiferus) musk deer are farmed in China and, of these, the forest musk deer is the main captive population. The present patterns of musk deer farming in China, however, need to be improved and developed into more economic and scientific modes in order to improve the rate of survival and reproduction, and to increase the production of musk.
Predicting intramuscular fat, moisture and Warner-Bratzler shear force in pork muscle using near infrared reflectance spectroscopy
Authors: Barlocco N. , Vadell A. , Ballesteros F. , Galietta G. , Cozzolino D. 
Published: February 2006

AbstractPartial least-squares (PLS) models based on visible (Vis) and near infrared reflectance (NIR) spectroscopy data were explored to predict intramuscular fat (IMF), moisture and Warner Bratzler shear force (WBSF) in pork muscles (m. longissimus thoracis) using two sample presentations, namely intact and homogenized. Samples were scanned using a NIR monochromator instrument (NIRSystems 6500, 400 to 2500 nm). Due to the limited number of samples available, calibration models were developed and evaluated using full cross validation. The PLS calibration models developed using homogenized samples and raw spectra yielded a coefficient of determination in calibration (R2) and standard error of cross validation (SECV) for IMF (R2=0·87; SECV=1·8 g/kg), for moisture (R2=0·90; SECV=1·1 g/kg) and for WBSF (R2=0·38; SECV=9·0 N/cm). Intact muscle presentation gave poorer PLS calibration models for IMF and moisture (R2<0·70), however moderate good correlation was found for WBSF (R2=0·64; SECV=8·5 N/cm). Although few samples were used, the results showed the potential of Vis-NIR to predict moisture and IMF using homogenized pork muscles and WBSF in intact samples.
Determination of the optimum dietary lysine concentration for boars and gilts penned in pairs and in groups in the weight range 60 to 100 kg
Authors: O'Connell M. K. , Lynch P. B. , O'Doherty J. V. 
Published: February 2006

AbstractThree trials were conducted to determine the optimum dietary lysine concentration for maximum growth rate (ADG) or minimum food conversion ratio (FCR) of boars and gilts from 60 to 90 kg (in pairs) and 80 to 100 kg (in pairs or groups). Ninety pairs of pigs and six treatments (dietary lysine concentrations) were used in experiment 1 (60 to 90 kg), 144 pairs and eight treatments in experiment 2 (80 to 100 kg) and groups of 13 pigs (no.=42 groups) and six treatments in experiment 3 (80 to 100 kg). Experiments were arranged as randomized-block designs, blocked on the basis of sex and start weight. Isoenergetic diets (13·8 MJ digestible energy per kg) were based on barley, wheat, soya-bean meal, with added vitamins, minerals and amino acids. Dietary lysine concentrations were: 7·9, 8·8, 9·7, 10·7, 11·7 and 12·5 g/kg in experiment 1; 7·0, 7·9, 8·8, 9·7, 10·7, 11·7, 12·5 and 13·5 g/kg in experiment 2; and 7·0, 7·9, 8·8, 9·7, 10·7 and 11·7 g/kg in experiment 3. In experiment 1 (60 to 90 kg pairs), ADG increased (quadratic, P<0·01) and FCR improved (quadratic, P<0·001) with increased lysine concentration. Although boars grew faster (P<0·001) and were more efficient (P<0·001) than gilts, maximum ADG was predicted at 10·8 g lysine per kg and minimum FCR at 10·9 g lysine per kg for all pigs. In experiment 2 (80 to 100 kg pairs), a treatment×sex interaction for ADG (P<0·01) and FCR (P<0·05) indicated that boars grew faster and had better FCR than gilts at dietary lysine concentrations above 10·7 and 9·7 g/kg respectively, with no difference between the sexes below these lysine levels. Maximum ADG was predicted at 11·8 and 9·9 g lysine per kg and minimum FCR was predicted at 11·9 and 10·0 g lysine per kg for boars and gilts, respectively. In experiment 3 (80 to 100 kg groups) ADG increased (quadratic, P<0·01) and FCR improved (quadratic, P<0·001) as dietary lysine concentration increased. Boars had higher ADG (P<0·001) and better FCR (P<0·001) than gilts. Maximum ADG and minimum FCR were predicted at 9·3 and 9·6 g lysine per kg for all pigs. In conclusion, boars grew faster and more efficiently than gilts, with interactions in experiment 2 indicating a greater difference in performance at higher dietary lysine concentrations.
Effect of dietary structure on animal performance and lesions in the ruminal wall and feet of Belgian Blue double-muscled bulls
Authors: de Campeneere S. , van Herck A. , Fiems L. O. , de Boever J. L. , Chiers K. , Ducatelle R. , de Brabander D. L. 
Published: February 2006

AbstractThe influence of the physical structure level in the diet on animal performance was investigated in 52 Belgian Blue doublemuscled bulls starting from a live weight of 348 kg until slaughter at about 645 kg. Four diets with different concentrate/maize silage ratios were offered ad libitum. The structural value (SV), developed in Belgium as a measure of physical structure in the diet for dairy cows, amounted to respectively 0.63 (HSV; high SV), 0.54 (MSV; moderate SV), 0.43 (LSV; low SV) and 0.34 (VLSV; very low SV) per kg dry matter.Growth rate, food intake and food conversion were all linearly affected by the decreasing SV of the diet. Among carcass parameters only the SEUROP conformation score showed a significant effect of the SV, with the MSV group having the highest score and VLSV the lowest. No important influence of the SV on the histological damage of the ruminal papillae or on the foot lesions was found.Based on the lower growth rate and food intake of the LSV group versus the HSV group, a SV of the diet between 0.54 and 0.43 is considered as an absolute minimum for Belgian Blue double-muscled bulls.
Splanchnic metabolism of volatile fatty acids in the dairy cow
Authors: Kristensen N. B. 
Published: February 2006

AbstractVolatile fatty acids (VFA) are quantitatively important substrates for dairy cows and other ruminants. It has been a central dogma in the nutritional physiology of ruminants that the ruminal epithelium metabolizes a large fraction of VFA during theirabsorption and consequently a relatively small fraction of VFA is available for peripheral tissues including the mammary gland. New data on splanchnic metabolism of VFA indicate that the ruminal epithelium metabolizes none or small amounts of acetate and propionate absorbed from the rumen. However, the ruminal epithelium has a large fractional uptake of butyrate and valerate during their absorption from the rumen. The liver takes up proportionately 0·9 or more of the absorbed propionate, however multiple factors are involved in regulation of hepatic metabolism and propionate does not determine glucose availability to the cowper se. In light of the quantitative importance of VFA to the dairy cow it is important that future research attempts to bridge the gap between the biology of food degradation/digestion in the gastro-intestinal tract and availability of specific nutrients to the cow which impact intermediary metabolism and nutrient utilizationin productive tissues.
Association of body weight, loinlongissimus dorsiand backfat with body condition score in dry and lactating Holstein dairy cows
Authors: Jaurena G. , Moorby J. M. , Fisher W. J. , Cantet R. 
Published: February 2006

AbstractThe lactation cycle of the dairy cow induces large changes in body fat and protein pools, which can be monitored through loin backfat (BF) and longissimus dorsi (LD) measurements. Data from two experiments (exp) using Holstein-Friesian dairy cows (no. = 40 and 32 respectively) were used to study the association of body weight (BW), BF and LD depth with body condition score (BCS) for the last 6 weeks of the dry period (DP) and the first 8 weeks of lactation. Loin and tail BCS were manually assessed (0 to 5 scale) and BF and LD depth were measured by ultrasound at the fifth lumbar process. The BCS data ranged from 1.3 to 3.0 units in the DP, and from about 1.1 to 3.1 units during early lactation in both experiments. Data were analysed by two models: BW, LD or BF = exp + period (DP or lactation) + BCS + interactions + cow + error (model 1); and BCS = exp + period + LD + BF + LD2+ BF2+ exp × LD + exp × BF + exp × LD2+ exp BF2+ period × LD + period × BF + period × LD2+ period × BF2BF2+ cow + error (model 2).A first-order autoregressive (AR(1)) covariance structure was employed for the error terms to account for the correlation among repeated measures within cow. Regressions of BW and LD on BCS (model 1) found pre- to post-calving differences (P< 0.001) in intercept for BW and LD, and slope coefficients of 35 (DP) and 21 (lactation) kg BW, and 5.8 mm LD per BCS unit. Regression of BF on BCS (model 1) showed an exp × period interaction (P< 0.001), with 0.4 mm BF (exp 1;P< 0.05) and 2.0 mm BF (exp 2;P< 0.001) per BCS unit. Regression of BCS on LD and BF (model 2) showed intercepts not equal to 0 (P< 0.06), and differences (P< 0.001) between DP and lactation; BCS increased (P< 0.001) by 0.027 units per mm BF and 0.05 units per mm LD, but LD had a quadratic term −0.0004 (P= 0.02). It is concluded that at BCS lower than 3, LD contributes to BCS following a quadratic function, whereas BF causes BCS to increase linearly. Each unit of BCS equated to about 35 and 20 kg BW for DP and lactation periods respectively, to 5.8 mm LD, and to between 0.4 and 2.0 mm BF.
A survey of waterfowl for echinostomes and schistosomes from Lake Wanaka and the Waitaki River watershed, New Zealand
Authors: Davis N.E. 
Published: February 2006

AbstractWaterfowl from Lake Wanaka and the Waitaki Lakes watershed of New Zealand's South Island were surveyed to find natural hosts with adult echinostomes and schistosomes to provide sufficient numbers of eggs for laboratory studies. The Canada goose (Branta canadensis) was found to host an echinostome determined to be a New Zealand strain of Echinostoma revolutum. The New Zealand scaup (Aythya novaeseelandia) concurrently hosts three species of echinostomes (E. revolutum, Echinoparyphium cinctum and E. recurvatum) plus two species of avian schistosomes (Trichobilharzia sp. and Dendritobilharzia pulverulenta). In the Canada goose and the New Zealand scaup, adult gravid echinostomes predominated over juveniles. In other waterfowl surveyed, very few echinostomes were found, with juveniles predominating.
Enzyme-linked immunosorbent assay with worm vomit and cercarial secretions of Schistosoma mansoni to detect infections in an endemic focus of Burkina Faso
Authors: Bahgat M. , Sorgho H. , Ouédraogo J.B. , Poda J.N. , Sawadogo L. , Ruppel A. 
Published: February 2006

AbstractCercariae and adult Schistosoma mansoni were used to prepare, respectively, cercarial secretions (CS) and worm vomit (WoV). These were used as antigens in an enzyme-linked immunosorbent assay (ELISA) to test the IgG-reactivity of sera obtained in an S. mansoni-endemic area of Burkina Faso. Among the egg-excreting individuals (n=240), 94.6% reacted positively with WoV, but only 62.9% with CS, thus suggesting a high diagnostic sensitivity of WoV, but not of CS. Among those individuals without detectable eggs in two Kato-Katz thick smears from different stool specimens (n=215), the respective percentages of positive IgG reactivity were 78.1% and 63.3%. These positive reactions in the absence of detectable eggs are interpreted in terms of limited sensitivity of parasitological stool examinations. Optical density values in ELISA with CS, but not with WoV, correlated negatively with age, which may reflect decreasing exposure to cercariae in older individuals.
Prevalence of amphistomiasis and its association with Fasciola gigantica infections in Zambian cattle from communal grazing areas
Authors: Phiri A.M. , Phiri I.K. , Monrad J. 
Published: February 2006

AbstractTo estimate prevalence of amphistomiasis and its association with bovine Fasciola gigantica infections in Zambia, 709 faeces of cattle presented for slaughter from three major cattle rearing areas of Central, Southern and Western provinces were analysed. The prevalence rate of amphistomes was 51.6%. Egg counts per gram (EPG) of faeces ranged from 0 to 385 with a mean (± SEM) of 11.96±1.07. The origin of the cattle had a significant influence (P<0.001) on the prevalence rate. Fasciola gigantica infections accounted for 46.7% of the cattle examined. The mean EPG count (± SEM) was 6.3±0.66 with a range of 0 to 223. A total of 34.6% were mixed infections while single Fasciola and amphistome infections represented 12.1% and 17.1%, respectively. Significantly more cattle (63.8%) were infected with either single or both trematode infections (P<0.0001) than not. Mixed trematode infections were highest in the Southern province (80.0%) while the lowest were recorded in Central province (16.3%). A positive correlation (r2=0.0428) was present in mixed infections. In order to minimize losses, epidemiology and cross-resistance of amphistomiasis and fascioliasis should be studied in different ecological regions of Zambia to formulate efficient control programmes.
Assessment of routine inspection methods for porcine cysticercosis in Zambian village pigs
Authors: Phiri I.K. , Dorny P. , Gabriel S. , Willingham A.L. , Sikasunge C. , Siziya S. , Vercruysse J. 
Published: February 2006

AbstractThe value of tongue and meat inspection as diagnostic tools for porcine cysticercosis was assessed in 65 Zambian village pigs by comparing the results with carcass dissections. In addition, the intensity of infections, distribution and viability of cysts in infected pigs were measured. Five pigs (7.7%) were positive on tongue examination, while routine meat inspection showed 12 (18.5%) positives. However, carcass dissections detected cysticerci in 31 (47.7%) pigs. The range in number of cysticerci was 1 to 14,662 per carcass. Cysticerci were distributed throughout the carcass with the highest concentration in the heart, tongue and hind legs. In one animal 13 viable cysts were detected only in the brain. Fourteen pigs had more than 100 viable cysts, six between 2 and 100, and four had single cyst infections. Seven animals harboured only calcified cysts. These findings demonstrate the serious shortcomings of routine detection methods for porcine cysticercosis. While the specificity of tongue palpation and meat inspection was 100%, these tests failed to detect the infection in 83.9% and 61.3% of infected pigs, respectively.