bluuebunny/crossref_metadata_2025_split huggingface dataset:
Stuart A. Selber : Qu’est-ce que la rhétorique numérique ?
Authors: Selber Stuart A. , Ridolfo Jim 
Published: April 2024

L’interview de Stuart Selber réalisée par Jim Ridolfo dans ce numéro spécial intitulé « La rhétorique en-dehors des sentiers battus » donne un aperçu de la carrière innovante et marquante de Selber dans le domaine de la rhétorique numérique. De la monographie primée de Selber, Multiliteracies for a Digital Age, parue en 2004, à sa toute dernière monographie Institutional Literacies : Engaging Academic IT Contexts for Writing and Communication, nous discutons de la manière dont les littératies et les paysages de la rhétorique numérique ont changé de manière significative et continueront à changer alors que nous entrons dans une ère où se multiplient les préoccupations en matière de protection de la vie privée, de deep fakes et d’IA générative. Le travail du professeur Selber est un excellent exemple de la façon dont la recherche en rhétorique numérique contemporaine révolutionne le domaine de la rhétorique traditionnelle et l’enseignement de la littératie, en réélaborant ses notions de base et en élargissant ses applications futures.
L’activité étudiante durant la crise sanitaire d’un point de vue ergologique : la question des initiatives prises par rapport à un champ de contraintes préexistantes
Authors: Denny Jean-Luc , Durrive Louis 
Published: April 2024

La pandémie de la Covid-19 constitue une urgence de santé publique. Si la majorité des études documente les effets délétères du confinement en termes d’apprentissages (accentuation des inégalités, décrochage, etc.), notre recherche se propose plutôt de mettre en visibilité des effets bénéfiques.Menée au cœur de l’événement entre mars et juin 2020, à l’heure du premier confinement en France, l’étude ambitionne d’instruire en quoi la rupture, produite par la transformation brutale du contexte d’enseignement, a pu faire expérience pour les apprenants en interprétant les faits par le prisme de la dialectique contrainte-initiative. En cohérence avec le point de vue anthropologique de Canguilhem sur l’activité humaine, le sujet de l’expérience est regardé selon une acception ergologique (Schwartz, 2000) comme un « corps-soi », qui est le concept d’unité de la personne vivant dans le monde et connaissant à travers son être tout entier.L’étude mobilise un groupe de huit étudiantes en licence 2 Sciences de l’Éducation et de la Formation. Le protocole de recherche se compose de deux focus groups et un entretien individuel intermédiaire par étudiante.Les résultats documentent comment les étudiantes entrent dans le champ des contraintes et reprennent l’initiative à trois niveaux : dans leur lien aux enseignants, dans leur relation au groupe de pairs et dans leur rapport aux savoirs. En définitive nous illustrons comment les étudiantes font l’expérience de l’autonomie, à distance de leurs repères habituels guidés par des enseignants habituellement perçus comme régulateurs et contrôleurs.
Penser la demande de changement culturel dans l’intervention ergonomique : défis et opportunités pour une démarche développementale
Authors: Nascimento Adélaïde 
Published: April 2024

L’appel au changement culturel n’est pas nouveau et comprend un vaste panel de cibles. La toile de fond concerne le plus souvent les besoins de modifications de comportements des personnes au travail ou dans la cité. Mais de quoi s’agit-il au juste ? L’objectif de cet article est de proposer des perspectives conceptuelles et méthodologiques pour penser les demandes de changement culturel dans l’intervention ergonomique. D’un côté, un défi se pose à l’ergonomie quant au positionnement de la discipline sur les usages de la notion de culture et sa prise en compte dans les interventions. D’un autre côté, une opportunité se présente pour les ergonomes, car l’intervention ergonomique peut se présenter comme un accompagnement de ce fait culturel au travail. À partir de ses méthodes d’analyse d’activité et de conception tournées vers le développement, l’ergonomie serait susceptible de contribuer à une analyse située des aspects culturels au travail. Partant de la théorie historico-culturelle de l’activité, le texte se fonde sur des exemples de trois recherches-interventions, et propose par là des voies pour accompagner le dynamisme culturel au travail.
La vidéo interactive, une voie de développement pour l’activité des personnels de direction
Authors: Veyrac Hélène 
Published: April 2024

Les managers de proximité sont amenés à organiser le travail d’agents tout en leur garantissant une qualité de vie au travail. Une tension entre ces deux enjeux a été vécue par un manager de proximité, proviseur adjoint d’un établissement d’enseignement, lorsqu’une enseignante lui a annoncé tardivement renoncer à accompagner un séjour scolaire pour difficultés privées qu’elle lui a exposées. Cette situation problème a servi de support pour une analyse du travail basée sur des simulations « en aveugle » de cette situation par sept autres managers de proximité et un chercheur. L’analyse des sept simulations permet de dégager des « issues » plus ou moins favorables à la qualité de vie au travail. La variabilité interindividuelle de l’activité en situation de simulation qui est mise en évidence structure la conception d’une vidéo interactive. Cette vidéo interactive est présentée. Elle vise à former à réduire les tensions évoquées. Les dimensions développementales des managers sont discutées sous l’angle des situations produites au cours du processus de conception de la vidéo interactive.
Représenter l’activité pour investiguer ses dimensions incarnée, spatio‑temporelle et collective
Authors: Bénézet Clémence , Leblanc Serge , Navarrete Mireille , Hossard Laure 
Published: April 2024

Les agriculteurs en transition agroécologique testent et ajustent de nouvelles pratiques culturales. Ce processus de conception pas à pas d’un nouvel agrosystème peut être analysé via la description et la compréhension de l’activité des agriculteurs sur différentes échelles spatiales et temporelles et en interaction avec de multiples acteurs humains et non humains. Notre étude porte sur le parcours d’intégration de la pratique d’entretien des sols par traction équine développé, sur un temps long, par le viticulteur en coopération avec un prestataire de service. Nous mobilisons le programme de recherche du cours d’action (Theureau, 2015) pour investiguer trois dimensions de l’activité : incarnée, spatio-temporelle et collective. 18 entretiens de différentes natures ont eu lieu auprès de 3 viticulteurs et 3 prestataires. Pour explorer chaque dimension, des représentations externes de l’activité, articulées avec différents objets théoriques et concepts, ont été élaborées et utilisées pendant ces entretiens pour favoriser l’expression de l’expérience située des acteurs. Cette étude aboutit à plusieurs résultats originaux. Sous réserve que le chercheur soit attentif à préserver les conditions favorables pour les acteurs, les représentations externes de l’activité permettent d’accompagner l’explicitation par les acteurs de leur activité située dans ses trois dimensions. Ces représentations favorisent les appropriations mutuelles entre acteurs et chercheur de l’objet de recherche renforçant la plausibilité des données construites pendant l’étude. Enfin, les modélisations multidimensionnelles de l’activité permises par ces représentations pourraient être une ressource pour accompagner la conception de nouvelles expériences collaboratives entre humains et non-humains sur le temps long avec et pour les agriculteurs.
La fiction au service du réel ? L’énonciation des récits de faits divers dans l’émission radiophonique Hondelatte raconte
Authors: Neuvillers Marie-Caroline 
Published: April 2024

Diffusée depuis 2016 sur Europe 1, Hondelatte raconte a su fédérer une communauté d’auditeurs fidèles autour de récits de faits divers racontés par son narrateur éponyme. Outre le contenu de ces histoires, le dispositif sonore et le ton du journaliste apparaissent comme des éléments clés du succès de l’émission : chaque récit repose sur l’incarnation de personnages par le narrateur, à travers des effets de voix mais aussi des sons d’ambiance et de la musique. En cherchant ainsi à produire un effet de réel, en matérialisant les événements et les actions racontés, la narration tend finalement à la fictionnalisation de ces récits.
Air Pollution Drives Macrophage Senescence through a Phagolysosome–15-Lipoxygenase Pathway
Authors: Thomas Sarah A , Yong Hwan Mee , Rule Ana M , Gour Naina , Lajoie Stephane 
Published: April 2024

Abstract
Urban particulate matter (PM; uPM) poses significant health risks, particularly to the respiratory system. Fine particles, such as PM2.5, can penetrate deep into the lungs and exacerbate a range of health problems, including emphysema, asthma, and lung cancer. PM exposure is also linked to extrapulmonary disorders such as heart and neurodegenerative diseases. Moreover, prolonged exposure to elevated PM levels can reduce overall life expectancy. Senescence is a dysfunctional cell state typically associated with age but can also be precipitated by environmental stressors. This study aimed to determine whether uPM could drive senescence in macrophages, an essential cell type involved in particulate phagocytosis-mediated clearance. Although it is known that uPM exposure impairs immune function, this deficit is multifaceted and incompletely understood, partly because of the use of particulates such as diesel exhaust particles as a surrogate for true uPM. uPM was collected from several locations in the United States, including Baltimore, Houston, and Phoenix. Bone marrow–derived macrophages were stimulated with uPM or reference particulates (e.g., diesel exhaust particles) to assess senescence-related parameters. We report that uPM-exposed bone marrow–derived macrophages adopt a senescent phenotype characterized by increased IL-1α secretion, senescence-associated β-galactosidase activity, and diminished proliferation. Exposure to allergens failed to elicit such a response, supporting a distinction between different types of environmental exposure. uPM-induced senescence was independent of key macrophage activation pathways, specifically inflammasome and scavenger receptors. However, inhibition of the phagolysosome pathway abrogated senescence markers, supporting this phenotype’s attribution to uPM phagocytosis. These data suggest that uPM exposure leads to macrophage senescence, which may contribute to immunopathology.
Behavioral prevention of HBV transmission in urban communities toward global elimination of hepatitis in 2030: a systematic review
Authors: Diniarti Fiya , Said Mohamed Saifulaman Mohamed , Rashid Norhashima Abd , Poddar Sandeep 
Published: April 2024

Hepatitis B is a serious threat to public health on a global scale. The Hepatitis B virus (HBV), which spreads both vertically and horizontally, is easily contracted by anyone. In 2020, the World Health Organization estimates that 257 million people worldwide have hepatitis B, and 900,000 people die from it each year. According to the World Health Organization (2021), there are approximately 39.4 million people in Southeast Asia living with chronic hepatitis B mortality, with 410,000 deaths caused by the disease. HBV can spread through injections, horizontal transmission, blood transfusions, and organ transplants. Cochrane, Science Direct, PubMed, Elsevier, Sage, Willey, DOAJ, and Google Scholar database sources were used to search for supported research on how to prevent hepatitis virus transmission in urban communities. 15 publications address the primary and secondary prevention of hepatitis B transmission in urban settings. Prevention keeps a person in good health and prevents them from progressing to a later, worse stage. Given that the hepatitis B virus can infect anyone, regardless of age, and that it affects people's health worldwide, as well as their families, communities, and families within them. In order to eradicate the hepatitis B virus, society must be aware of the importance of implementing preventive measures on a continuous and long-term basis through health advocacy activities, hepatitis B virus screening campaigns, health education, counseling, hepatitis B vaccination with community-based activities, and secondary prevention through combination therapy treatment in post-liver transplant patients.
Association between statin use & risk of diffuse large B-cell lymphoma: A systematic review & meta-analysis
Authors: Ponvilawan Ben , Charoenngam Nipith , Ungprasert Patompong 
Published: April 2024

Background & objectives:
Statin use has been shown to be associated with a decreased risk of several types of cancer, however, the data on diffuse large B-cell lymphoma (DLBCL) are still inconclusive. This study aimed to systematically summarize all available data on this association and conduct a meta-analysis on the same.

Methods:
A systematic review was performed using EMBASE and MEDLINE databases from inception upto October 2019 with a search strategy that included terms such as ‘statin’ and ‘DLBCL’. Eligible studies included either case–control or cohort studies that reported the association between statin use and the risk of DLBCL. Relative risk, odds ratio (OR), hazard: risk ratio or standardized incidence ratio of this association and standard error were extracted and combined for calculating the pooled effect estimate using random-effects, generic inverse variance method.

Results:
A total of 1139 articles were screened. Of these six studies satisfied the inclusion criteria and were included for the meta-analysis. Statin use was associated with a significantly reduced risk of DLBCL with the pooled OR of 0.70 (95% confidence interval, 0.56-0.88; I
2=70%). The funnel plot (fairly symmetric) was not suggestive of the presence of a publication bias.

Interpretation & conclusions:
The present systematic review and meta-analysis found that statin use is associated with a 30 per cent reduced odds of DLBCL. However, the pooled analysis utilized data from observational studies so causation cannot be concluded upon. Hence, it suggested that randomized-controlled studies are still needed to confirm this potential benefit.
Normative data for paediatric lymphocyte subsets: A pilot study from western India
Authors: Jodhawat Neha , Bargir Umair Ahmed , Setia Priyanka , Taur Prasad , Bala Nidhi , Madkaikar Aditi , Yadav Reetika Malik , Dalvi Aparna , Shinde Shweta , Gupta Maya , Shelar Shraddha , Kambli Priyanka , Gowri Vijaya , Lokeshwar Madhukar , Satoskar Purnima , Desai Mukesh , Madkaikar Manisha 
Published: April 2024

Background & objectives:
Accurate diagnosis of immunodeficiencies requires a critical comparison of values with age-matched controls. In India, the existing reference values for rare lymphocyte subsets are currently not available and we rely on the data originating from other countries for the interpretation of the results. Furthermore, there is limited information on normal variation for these rare-subset parameters in Indian children. So, this study aimed to establish normative values for clinically important lymphocyte subsets in Indian children at different age groups.

Methods:
148 children aged ≥16 yr were enrolled in this study. The study population included 61 per cent males and 39 per cent females and was divided into the following groups: cord blood (n=18), 0-6 months (n=9), 6-12 months (n=13), 1-2 yr (n=19), 2-5 yr (n=27), 5-10 yr (n=25) and 10-16 yr (n=37). The absolute and relative percentage of lymphocytes, T, B, natural killer cell, along with activated, naïve and memory subsets, was determined by flow cytometry.

Results:
Median values and the 10th and 90th percentiles were obtained for 34 lymphocyte sub-populations. The T and B naïve compartments showed a decreasing trend, whereas memory cells showed an increase with age. The activated T cell subset shows an increasing pattern up to one year and then declines gradually. Double negative T cells are relatively stable. TCRgd+T cell percentage increases with age.

Interpretation & conclusions:
This single-centre pilot study provides preliminary data that justifies the need for future large-scale multi centric studies to generate a reference range for interpreting extended immunophenotyping profiles in the paediatric age group, making it possible for clinicians to assess the immunological status in inborn errors of immunity, infectious and autoimmune diseases.
Hospital-acquired infections due to carbapenem-resistant Providencia stuartii
Authors: Sharma Swati , Pramanik Sangita , Marndi Pooja , Banerjee Tuhina 
Published: April 2024

Background & objectives:
During the course of a retrospective survey on healthcare associated infections (HAIs) due to carbapenem-resistant organisms, an unusual prevalence of HAIs due to carbapenem-resistant Providencia stuartii (CRPS) was found. Hence this study aimed to conduct the occurrence of P. stuartii associated HAIs with special reference to the drug resistance profiling of these isolates.

Methods:
Of the eight total HAI cases (7.5% of total HAIs and 33.3% of HAIs due to Enterobacterales) of CRPS infections included in this study, three were reported from ventilator-associated pneumonia (VAP), three were surgical site infections (SSIs), one was a catheter-associated urinary tract infection (CAUTI) and one was a bloodstream infection. All the eight CRPS isolates were tested for extended-spectrum β-lactamases production, AmpC hyperproduction as well as carbapenem resistance. Typing of the isolates was performed by repetitive extragenic palindromic polymerase chain reaction (REP-PCR).

Results:
All the eight isolates of CRPS were found to be AmpC hyperproducers, carbapenemase producers, and harboured chromosomally located bla
NDM in seven isolates and bla
IMP genes in one. All the cases with CRPS infections had prior history of colistin therapy along with prolonged hospital stay (>20 days). The cases were located in five different wards/intensive care unit (ICU) within the hospital in one year. However, strain typing by REP-PCR revealed 100 per cent similarity and clonal relatedness in all the seven isolates carrying bla
NDM genes. Interestingly, routine hospital surveillance revealed a high carriage of P. stuartii in the axilla of patients admitted to the ICU.

Interpretation & conclusions:
The study findings suggest CRPS as an important cause of HAIs. This organism often goes unnoticed due to the burden of carbapenem resistance in other Enterobacterales and non-fermenters.
Aetiology of hospital-acquired diarrhoea in under-five children from an urban hospital in East Delhi, India
Authors: Singh Nupur , Shah Dheeraj , Singh Taru , Saha Rumpa , Das Shukla , Datt Shyama , Gupta Piyush 
Published: April 2024

Background & objectives:
Majority of the studies of hospital-acquired diarrhoea conducted in Western countries have focused on the detection of Clostridium difficile in stool samples. Limited Asian and Indian literature is available on hospital-acquired diarrhoea. This study was aimed to describe the aetiological profile for hospital-acquired diarrhoea in children aged below five years.

Methods:
One hundred children aged one month to five years who developed diarrhoea (≥3 loose stools for >12 h) after hospitalization for at least 72 h were enrolled. Children who were prescribed purgatives or undergoing procedures such as enema and endoscopy or those with underlying chronic gastrointestinal disorders such as celiac disease and inflammatory bowel disease were excluded from the study. Stool samples from the enrolled children were subjected to routine microscopic examination, modified Ziel-Nielson (ZN) staining for Cryptosporidium and culture for various enteropathogens. Multiplex PCR was used to identify the strains of diarrhoeagenic Escherichia coli. Rotavirus detection was done using rapid antigen kit. Toxins (A and B) of C. difficile were detected using enzyme immunoassay.

Results:
Of the 100 samples of hospital-acquired diarrhoea analysed, diarrhoeagenic E. coli (DEC) was found to be the most common organism, detected in 37 per cent of cases (enteropathogenic E. coli-18%, enterotoxigenic E. coli-8%, enteroaggregative E. coli-4% and mixed infections-7%). Cryptosporidium was detected in 10 per cent of cases. Rotavirus was detected in six per cent and C. difficile in four per cent of cases.

Interpretation & conclusions:
The findings of this study suggest that the aetiological profile of hospital-acquired diarrhoea appears to be similar to that of community-acquired diarrhoea, with DEC and Cryptosporidium being the most common causes. The efforts for the prevention and management of hospital-acquired diarrhoea should, thus, be directed towards these organisms.
Study of central aortic blood pressure in hypertensive patients & its relation with blood pressure-lowering drugs
Authors: Sachan Dhyanendra , Sawlani Kamal Kumar , Kumar Amit , Chaudhary Shyam Chand , Dandu Himanshu , Usman Kauser , Atam Virendra 
Published: April 2024

Background & objectives:
In clinical settings, peripheral blood pressure (PBP) is measured routinely. It is thought that central blood pressure (CBP) which reflects aortic BP, may be more predictive of outcomes in specific populations. Hence, this study was carried out to measure CBP in patients with hypertension and to see the effect of antihypertensive drugs on CBP.

Methods:
This cross-sectional study was conducted on 134 hypertensive patients and 134 normotensive healthy individuals as controls. Peripheral BPs and CBPs were measured of all patients and controls. The data were correlated and the effect of antihypertensive drugs on CBP was also evaluated.

Results:
Of the 134 hypertensive patients, 44 (32.84%) were newly diagnosed and the rest 90 (67.16%) had a history of hypertension and were on treatment. Of these 90 patients on treatment, 37 (41.11%) had uncontrolled peripheral BP and 53 (58.89%) had normal peripheral BP. Of the 134 hypertensive patients, 45 (33.58%) had controlled CBP. In 90 patients, who were on antihypertensive treatment, 45 (50%) had controlled CBP and 45 (50%) had uncontrolled CBP. Patients on calcium channel blockers (CCBs) had better control of CBP.

Interpretation & conclusions:
Hypertension is diagnosed mainly by measuring peripheral BP. CBP, which correlates better with the incidence of cardiovascular events, is not routinely measured. Patients with a history of hypertension and on treatment had normal office peripheral BP, but a few of them had high CBP and may require modification in treatment for control of CBP. Control of CBP was better in patients taking CCB.