bluuebunny/crossref_metadata_2025_split huggingface dataset:
Le Nanisme avec oligurie et oligodipsie
Authors: DEBRÉ ROBERT 
Published: January 2008

ResuméAvec J. MARIE, nous avons, en 1937, décrit un syndrome caractérisé par l'association possible d'un nanisme avec un trouble du mktabolisme de l'eau s'opposant point à point à celui du diabète insipide hypothalamo‐post‐hypophysaire: oligodipsie, oligurie, opsiurie, concentration urinaire é1evé en permanence.Nous avons observé personnellement quatre cas de ce genre. G. DOLIVO en a rapporté trois et M. LAMP un. II semble bien btabli que ce syndrome est liéà une insuffisance globale du lobe antbrieur de l'hypophyse. Nons avons, avec P. ROYER, J. J. ALLOITEAU et A. SPAHR, essayé de fournir cette demonstration et nous exposons ici les arguments qui plaident en faveur de cette hypothése.L'antidiurkse aqueuse entrainée par l'insuffisance anté‐hypophysaire pose des problèmes que les cliniciens ont jusqu'ici peu explorés et que les physiologistes n'ont pas encore parfaitement résolus.Dans un de nos cas, la correction des troubles du métabolisme de l'eau parl'administration de cortisone, d'ACTH et de désoxycorticostérone laisse penser, si notre observation est vérifiée, que le déficit en ACTH est responsible du syndrome d'oligurie et oligodipsie, qui accompagne ce nanisme particulier.
Beiträge zur Pathologie der Blutgerinnung
Authors: FANCONI G. 
Published: January 2008

ZusammenfassungEs werden folgende Beiträge zur Gerinnungspathologie aus dem Kinder‐spital Zurich zusammengefasst:1 Hinweis auf die untersuchungen Cramersümophilie B (Christ mas disease).2. Drei Fäille von liypocalcämischer Gerinnungsstärung, wobei offengelassen wird, ob die Gerinnungsstärung die direkte Folge der Hypocalcamie ist oder ob es sich nur um ein zufälliges Zusammentreffen handelt.3. Kurzbericht äber zwei Fälle von akutem Factor‐V‐Mangel, welche unter dem Bilde der postscarlatinösen Purpura fulminans einhergingen; der eine Fall konnte durch eine Exchange transfusion gerettet werden.4. Bericht iiber die Aufklärung der Gerinnungsstörung im Verlauf der Coeliakie, welche zuerst als Scorbutoid (1937), dann als Hypothrombinämie (1928) geschildert wurde, und schliesslich 1938 als Hypoprothrombinamie infolge Störung der K‐Vitaminresorption aufgeklärt wurde.5. Beschreibung eines Falles von idiopatischer permanenter Hypoprothrombinämie, der nur durch Bluttransfusion am Leben erhalten werden konnte.6. Bericht über eine eigenartige Dysproteinämie im Verlaufe schwerer Leberstörungen bei Lues congenita und bei Sympathogonioni mit Metastasen in der Leber. Fanconi schlug 1941 den Namen Fibrinasthonie vor. Die Niederschlage im Blutausstrich bestehen jedoch nicht aus Fibrin, sondern stammen aus der Gammaglobulinfraktion, die Makroglobulincharakter (WILLI und KOLLER) hat. Das Fibrinogen ist auch stark vermehrt, es ist aber noch nicht geklärt, ob die Fibrinbildung gehenimt ist.
Folic Acid Antagonists and ACTH in the Treatment of Leucemia in Children.
Authors: FOGHT‐NIELSEN K.‐E. , FRIIS‐HANSEN B. , PLUM M. 
Published: January 2008

SummaryBy treatment of 22 children with acute leucemia by ACTH and/or folic acid antagonists, complete and partial remissions have been obtained in 13 patients, in a total number of 32. The average survival time of all these 22 patients is 7 months, and that of the 13 who got remissions, 10 months. Twenty‐two patients from an earlier period survived 4 months on an average.The best results have been obtained by alternating treatment by ACTH initially and at relapses and a‐methopterin in maintenance dosages during the remissions.The burden and painfulness of the disease seem to be relieved by the treatment even if the final result is unaltered.
Zur Kenntnis der Cystinosis
Authors: FREUDENBERG E. , ROULET F. 
Published: January 2008

Zusammenfassung1. Klinischer und pathologisch‐anatomischer Bericht über einen neuen Cystinosefall nebst Ergänzungen zu fruheren Beobachtungen.2. Hinweis auf das Vorkommen von Nadelformen und Versuch dasselbe zu erklären. Differenzen der Lokalisation und Verteilung gegenüber den Cystinplättchen sowie die positive Tyrosinasereaktion berechtigen vorläufig zur Annahme, dass Tyrosin vorliegt.
The Incidence of Involuntary Marital Childlessness
Authors: GYLLENSWÄRD CURT 
Published: January 2008

SummaryThe incidence of involuntary marital childlessness has long been given, and is still given, as 15 to 10 per cent. Approximately this incidence is, in fact, found in marriages with a minimum duration of 15 years in investigations made in Scandinavia both around 1890 and 1930.It is demonstrated that the incidence was, in reality, only about 3 per cent, in marriages of at least 15 years' duration and a maximum age of the wife at rnaxriege of 30 years, in a population in the midlands of Sweden, comprising both urban and rural districts, during the 18th and 19th centuries. This figure also applies in the following cases: the whole population of Sweden in the census of 1930; in marriages of at least 15 years' duration and a maximum age of the wife at marriage of 30 years, in all marriages‐irrespective of the duration—in a limited, well—situated population group in rural districts in Sweden in 1930; and in marriages of 10–15 years' duration, and an age at marriage of 20–24 years, in a population employed in agriculture and subsidiary occupations in the census of the same year. The actual involuntary infertility niay be presumed to be still lower, since stillbirths, many deaths in early infancy, and abortions are not included.It is shown that a successive displacement of not inconsiderable extent has occurred, in that voluntary childlessness is practised during a longer period of the marriage, and thus until the wife is older than was formerly the case. This also applies in marriages in which a t least one child is eventually born. Even during the 19th century, a tendency is found—which thereafter has increased successively—for the wife to be disinclined to give birth to a child at this higher age and, in fact, as soon as after 25–30 years of age. The possible influence of this factor on later attempts to conceive is discussed.It is concluded that the view that voluntarily completely childless marriages are rare on psychological grounds has presumably long ceased to be generally applicable to large population groups in Sweden.It is pointed out that it is incorrect, from the point of view of population policy, to withhold social benefits—such as the children's allowance—from the first child, and to base such a policy on the hope that efforts will always be made to have at least one child.
Sucrosuria with Mental Defect and Hiatus Hernia
Authors: MONCRIEFF ALAN , WILKINSON R. H. 
Published: January 2008

SummaryThree instances are described of the association in early childhood of sucrosuria, mental retardation and an anomaly of the lower end of the ocsophagus, thus producing the three types of congenital abnormality in the one subject—inborn metabolic error, mental defect and an anatomical abnormality. Autopsy findings in one case revealed a congenital defect in the brain, thus ruling out any hypothesis that the mental retardation might be associated with a sucrosaemia. It is concluded that the sucrosuria resulted essentially from rapid absorption of the unsplit disaccharide but technical difficulties made it impossible to investigate further the failure of splitting or its degree. The previous, scanty, literature mostly deals with similar instances, as far as the sucrosuria is concerned, of exogenous origin. Careful study of the sugars fed and subsequently passed in the urine revealed a more complicated story than that of excessive alimentary absorption of sucrose and urinary excretion. Provisional “normal” values for urinary sugars obtained by chromatography are suggested. The close association of lactose and sucrose in the diet in relation to the occurrence of sucrose in the urine seems definitely established in the cases reported. Glucose metabolism was unaffected
Um das Waterhouse‐Syndrom
Authors: RUDDER B. DE 
Published: January 2008

ZusammenfassungDas “Waterhouse‐Syndrom” ist ausschliesslich ein pathologisch‐anatomischer Begriff, niimlich Bezeichnung für eine mit Nebennierenlasion einher‐gehende foudroyante Sepsis. Da der Krankheitsablauf auch ohne diese Läsion in gleicher Schwere erfolgen kann, ist durch diese Bezeichnung über die nosologische Bedeutung der Lasion nichts ausgesagt. Wer ihr einen entscheidenden Einfluss auf den Krankheitsverlauf zuschreiben will, mag bei nachgewiesener Nebennierenblutung weiter von Waterhouse‐Friderichsen‐Syndrom sprechen; er muss sich dann nur darüber klar bleiben, dass diese Annahnie vorerst eine rein hypothetiache ist, für die er den Beweis schuldig bleibt.
Ascariasis in the Tropics
Authors: SILVA C. C. DE 
Published: January 2008

SummaryAscaris is one of the most prevalent and dangerous diseases of children of all underdeveloped countries. This is due to poverty, ignorance, low standards of sanitation and hygiene, especially the pollution of the soil by younger children. The problem is not only medical but socio‐economic as well. The chief hope of an early improvement lies in the discovery and use by public health authorities of a cheap ovicidal drug which can be sprayed on the soil and on the floors of houses.Ascaris lunibricoides is the commonest intestinal parasite seen in children between 1–10 years of age, its chief incidence lying between the ages of 1–6 years. The clinical syndromes are fully described and classified under (1) Gastro‐intestinal [medical or surgical], (2) Respiratory, (3) Nervous, (4) Pyrexial with enlargement of the liver, (5) Atypical and unusual cases due to migration of adult worms and larvae, and (6) Allergic.Treatment is indicated briefly. Santonin, Hetrazan, Banocide and Hexylresorcinol are the only drugs used by us. No vermifuges should be given to cases that me seriously ill with vomiting or toxaemia or have massive infestations till these disorders have first been overcome.
The Iodine Content of Human Milk in Finland
Authors: LAHESMAA PIRKKO , VILKKI PANU 
Published: January 2008

SummaryThe idoine content was determined in samples of mother's mil obtained from two areas of Finland which differ in the incidence of goitre. The mean iodine content of goitre. The mean content of mother's milk was found to be 53.3±1.4 μg/L in 107 milk samples from 42 mohers in the non‐goitrous Turku area and 25.1±μ/L in 18 milk samples from 18 mothers in the goitrous Kuopio area. The difference between the two mean values is highly significant. The mean iodine content of samples taken in August was lower than that of samples taken in December, but this difference was statistically significant in the Turku area only. No convincing daily rhythm was observed in the iodine content of the milk and the level of the protein bound iodine in the serum of the mother.
Hymenal Polyps in Newborn Infants
Authors: BORGLIN NILS ERIK , SELANDER PER 
Published: January 2008

SummaryPolypoid formations originating from the dorsal edge or dorsal margin of the hymen or just cranial to it occur in about 6% of all newborn girls. They consist of embryonal rests of the uro‐rectal septum. These polyps are always benign and disappear spontaneously within a few weeks.
A Clinical and Electroencephalographic Study of a Pair of Monozygotic Twins with Phenylketonuria
Authors: HERRLIN KARL‐MAGNUS 
Published: January 2008

SummaryA pair of monozygotic male twins with phenylketonuria, born in 1943, and reared together, were studied clinically and with EEG. Their oligophrenia, epilepsy and EEG findings show appreciable differences. One twin has relatively high intellectual capacity (IQ 55) and 3 per second spike and wave epilepsy, whereas the other is a low grade imbecile (IQ 26) with epilepsy of a focal type. The only known lesional factor is their metabolic disturbance.
Morbidity and Mortality among Infants under Supervision at Child Welfare Centres and Non‐Supervised Infants
Authors: KARLSTRÖM FRITZ 
Published: January 2008

SummaryDuring the five‐year periods 1944–1948 and 1956–1960, 23,450 and 19,699 infants, respectively, were born in the province of Värmland. Of these, 93% and 95% respectively were registered at child welfare centers. Using admissions at the paediatric clinic of Karlstad Hospital as a basis, the morbidity and mortality rates for certain diseases were calculated. The incidence of these diseases among infants between 3 and 12 months of age who attended or did not attend these centres is presented. It was found that for all disease groups, the morbidity was very much higher among the infants not under control at the centres. This was particularly evident in the rickets and tetany group. Mortality was also much higher among the non‐supervised infants. The activities of the welfare centres cannot be entirely responsible for these results. This investigation clearly indicates, however, that the centres are of great significance to infant health. In addition, their importance did not lessen during the 12 year interval between the two 5‐year periods. The children not under supervision are, in general, in poorer physical condition than those registered at the welfare centres, and everything possible should be done to improve their situation.
Mental Development Following Maternal Rubella: A Follow‐Up Study of Children Born in 1951–1952
Authors: LUNDSTRÖM ROLF , AHNSJÖ SVEN 
Published: January 2008

SummaryChildren of mothers who had contracted rubella in early pregnancy in 1951–1952 showed a higher incidence of subnormal head circumference than did control children. They also showed a delayed functional development, as judged from the age at which they sat and/or stood by themselves. “School‐maturity” tests were performed in 449 children with histories of maternal rubella in the first five months of pregnancy and in 403 controls at 7 years of age. Of 78 children with histories of rubella in the second month of pregnancy, 26% were “school‐immature”, compared with 13% of the 403 controls. This difference was significant. No such differences were observed for the first‐, third‐, fourth‐ and fifth‐month rubella children, but for the third‐month group a tendency was noted. Of 120 second‐month rubella children and of 153 third‐month children, 13% and 11% respectively had a record of school entry postponement, compared with 3% of 629 controls. Of the 120 second‐month children, 30% were assigned by their teachers to the bottom third of the class, as against only 21% of the controls. These differences were significant. No such differences were demonstrable among the first‐, fourth‐ and fifth‐month rubella children, as compared with the controls. The results of this investigation have underlined the need for a psychometric study of a limited number of the children here reported. Such a study will be reported in the near future.
Cytomegalic Inclusion Disease: A Report of Two Cases
Authors: ROBERTSON BENGT , SUNDELIN PÄR 
Published: January 2008

SummaryTwo cases of generalized cytomegalic inclusion disease are reported. The first was a 5‐day‐old boy with gastro‐intestinal symptoms and multiple perforation of the small intestine. Autopsy disclosed advanced cytomegalic changes in the kidneys, and dispersed inclusions in the lungs, liver, pancreas and hypophysis. The other case was a 7‐week‐old boy with a clinical picture of respiratory distress, who died after three weeks of respirator therapy. The autopsy showed interstitial pneumonia and cytomegalic changes in the lungs, kidneys and liver. With regard to the possibility of diagnosing the disease intra vitam by cytologic analysis of the urinary sediment, the presence of isolated cytomegalic cells in renal tubules is a feature of interest in both these cases.
Consumption of Calories and Nutrients by Diabetic and Non‐Diabetic Schoolchildren: A Dietary Study Based on the 24‐Hour Recall Method
Authors: STERKY GÖRAN 
Published: January 2008

SummaryVarious dietary study methods in common use are discussed and the results of an investigation carried out among all juvenile diabetics in Stockholm and matched controls are given. The 24‐hour recall method is applied for 252 children and the results are compared with the recommended allowances given by the U.S. National Research Council.Both for calories and nutrients, most of the figures in the various age groups and materials are below the given norms. The diabetics had a lower caloric consumption than the controls and, especially the girls, were unfavourably situated as regards certain nutrients. The school lunch gave satisfactory intakes among the non‐diabetics for all nutrients except iron and ascorbic acid. Higher protein and lower carbohydrate percentages were observed among the diabetic boys as compared with the non‐diabetics, but there was hardly any difference among the girls. Both non‐diabetic girls and boys had a high fat consumption. The results of a comparison between groups of diabetic children given different dietary prescriptions are discussed.It is concluded that children with diabetes mellitus need much instruction and teaching to give satisfactory quality to their diet.
Anorexia and Brain Tumour
Authors: BRANDBERG OLOF 
Published: January 2008

SummaryTwo sisters, who resembled each other, both fell ill, at the age of three years, from progressive anorexia, which, during a course of about two and three years respectively, proved fatal. The elder sister died in her home and had then suffered from epileptic seizures, indicating a brain lesion. This had previously been conjectured; most probably a brain tumour may be suspected. The younger sister died from severe prostration at the hospital. In her case there were EEG changes which could indicate tumour cerebri; this suspicion was confirmed post mortem.
Transplacental Metastasis of Malignant Melanoma
Authors: CAVELL BERTIL 
Published: January 2008

SummaryA case of probable transplacental metastasis of malignant melanoma from mother to fetus is described. At 2 months of age the infant displayed soft tissue tumors and pulmonary lesions, metastasization of malignant melanoma having occurred shortly before delivery in the mother. The lesions in the infant were thought to be metastasis. These lesions disappeared within a few weeks and on examination at 2 years the child appeared healthy. Observations made in this case and three similar ones in the literature suggest that the induction of immunological tolerance during gestation may play a role in the prognosis of tumor disease in the infants.
Evaluation of the Prontosil Liver Test in Newborns and Infants
Authors: KJELLMAN BENGT 
Published: January 2008

SummaryThe value of the prontosi! liver function test was studied in newborns and infants. The excretion of prontosil with urine was found to be significantly higher during the first year of life than later. Whether this difference should be ascribed to a lower secretory capacity of the liver is uncertain, because the result of the test is not dependent on liver function alone but also on other factors. No difference of the results was found between newborns with so called idiopathic hyperbilirubinaemia and normal newborns. The wide variation of the results of the test in newborns and infants above the newborn period limits the value of the test for this age.
Acquired Toxoplasmic Encephalitis
Authors: SJÖVALL KJELL , KÖHLER LENNART 
Published: January 2008

SummaryDescription of a case of psychic complaints in an 11‐year‐old schoolgirl, where the anamnesis and clinical picture, spinal fluid changes, EEG, and nystagmographic changes, and toxoplasmic titers strongly suggest a diagnosis of acquired toxoplasmic encephalitis.
Allergic Children with Various Symptoms Caused by Cow's Milk
Authors: WILKEN‐JENSEN KNUD 
Published: January 2008

SummaryEight children from four months to twelve years of age with various symptoms from skin, nose, ears, blood and the gastrointestinal tract are described. The symptoms seem to have been provoked by an allergy to milk and milk products and were demonstrated by elimination diet and provocation tests. It is pointed out that these tests must be repeated if necessary, to ensure their reliability. These patients may or may not have an allergic history, eosi‐nophilia and positive cutaneous reactions.
2. Icterus Neonatorum. Pathological‐Anatomical Considerations
Authors: TYGSTRUP I. 
Published: January 2008

SummaryIn a collection of 19 cases of kernicterus the pathological‐anatomical changes have been studied. Alterations were found in the globus pallidus, nucleus subthalamicus, hippocampus and to a slighter degree in the thalamus. No changes were found in the putamen and nucleus caudatus. The correlation with clinical findings is dicussed.
Cystinuria and Cystine Urolithiasis in Childhood
Authors: PRUZANSKI W. 
Published: January 2008

SummaryAmong 56 cases of cystinuria, in fifteen (2700) the disease was discovered at the preadolescent age. Eight out of 21 cases of cystine urolithiasis began to suffer in their childhood, which gave the rate of 3800‐much higher than it is usually encountered in the literature. Renal colic, hematuria, urinary retention and urinary tract infections may appear very early and lead subsequently to renal failure. The stones are almost always bilateral and multiple. Repeated surgical procedures are frequent.Cumulative data on 31 children with cystine stones and prolonged follow‐up in 24 of them showed that the disease is serious and sometimes fatal. Four patients with cystine lithiasis died a t young ages, which gives a mortality rate of 13%.An infant with bilateral cystine lithiasis and hypertension expired at the age of 7 months, is a unique and youngest case, reported in the literature.It seems that cystinuria and cystine lithiasis are more frequent in infancy and childhood than it was believed before and that it is a serious and sometimes fatal disease. Consequently, in each discovered case a regular and prolonged therapy should be undertaken.
Total Tracheopulmonary Agenesis Associated with Asplenia, Agenesis of Umbilical Artery and Other Anomalies
Authors: DEVI BANTI , MORE J. R. S. 
Published: January 2008

SummaryA case of bilateral pulmonary agenesis and the first of total tracheopulmonary agenesis, is reported. In addition to absence of the lower portion of the larynx, trachea and lungs, there were several cardiac abnormalities, including a common atrio‐ventricular valve, persistent ostium primum, interventricular septa1 defect, truncus arteriosus and absence of both pulmonary trunk and arteries. Additional malformations present included a persistent left superior vena cava, left azygos vein, absence of the spleen, gastric hypoplasia and a hemivertebra. The embryology of the defects in the present case is discussed with particular reference to their time of onset and causation and the important findings compared with those of previously published cases. It is suggested that inception of splenic development may occur earlier than has previously been postulated.
Arthrogryposis Multiplex Congenita A Case of Neurogenic Origin
Authors: VESTERMARK BIRGIT 
Published: January 2008

SummaryA case of arthrogryposis multiplex congenita in a girl, who died three days old, is described. Microscopy of the spinal cord revealed total loss of the motor cells of the anterior horn. The characteristics of this neurogenic disorder and its relation to myogenic a.m.c. and to Werdnig Hoffmann's disease are discussed.
Evidence from Bone Growth that Most of the Infants Dying in the Neonatal Period had been 111 Before Birth
Authors: EMERY JOHN L. 
Published: January 2008

SummaryA survey of the pattern of growth, as revealed by the structure of the costo‐chondral junction, suggests that the great majority of infants dying in the neonatal period had intrauterine disease antedating labour. This involves approximately 60% of premature birth deaths and around 75 % of perinatal deaths at term.