bluuebunny/crossref_metadata_2025_split huggingface dataset:
Primary chondroid chordoma arising from the base of the temporal bone
Authors: Hasegawa M. , Nishijima W. , Watanabe I. , Nasu M. , Kamiyama R. 
Published: November 2007

AbstractA 36-year-old male with a primary chondroid is presented. This tumour arose from the base of the temporal bone and extended to the mastoid cavity. It involved the facial nerve and was adherent to the internal jugular vein and internal carotid artery. The tumour was excised and the patient has been carefully followed up for 10 years. He has shown no evidence of local recurrence, intracranial extension of the residual tumour and distant metastasis.
The elongated styliod process as a cause of throat discomfort
Authors: Lindeman Pontus 
Published: November 2007

AbstractPain in the neck, radiating towards the ear, together with a foreign body sensation in the throat is a common complaint. A less common finding upon physical examination is an elongated styloid process, palpable in the tonsillar fossa and provoking the symptoms for which the patient is seeking medical advice. The diagnosis of this so-called Eagle's sundrome is described and the case history and treatment of four patients are presented.
Middle-ear lipoma presenting as airways obstruction:
Authors: Stegehuts H. R. , Guy A. M. , Anderson K. R. 
Published: November 2007

AbstractWe report a case of a lipoma arising in the middle ear of a 64-year-old woman and extending down the eustachian tube to cause acute airways obstruction. The lipoma arose coinciden-tally after a stapedectomy operation and caused apparent late failure of the operation. A review of the literature revealed no similar cases.
A controlled study of the suppression of tinnitus by lidocaine infusion: (Relationship of therapeutic effect with serum lidocaine levels)
Authors: Perucca E. , Jackson P. 
Published: November 2007

SummaryThe relationship between serum lidocaine levels and tinnitus relief was assessed in 5 patients during intermittent intravenous infusions of the drug. Experiments were conducted under controlled conditions in that neither the attending physician nor the patient was aware of whether active drug or placebo was being infused at any particular time. A significant relationship between serum level and effect was observed in two patients. In the remaining patients this relationship was not readily apparent but there was still a trent for a better response to be seen at higher levels. A satisfactory response was generally seen at levels above 1 μg/m1. The results are consistent with the hypothesis that the transient nature of the symptomatic relief caused by lidocaine is related ot the fast clearance of the drug from the body.
Nasal fractures in children: influence on the development of the nose
Authors: Grymer Luisa F. , Gutierrez Carolina , Stoksted Poul 
Published: November 2007

SummaryFifty-seven patients between the ages of zero and 16 years, treated for nasal fractures during childhood by means of closed reduction, have been subjected to follow-up examination after development of the nose has ceased. These patients have been compared to a control group of 50 persons without any known nasal trauma. No difference was found between the two groups with regard to functional complaints, but deviations of the osseous and cartilaginous pyramid, humps and sáddle formations, as well as spine formations and deviations of the septum, were particularly prevalent in the fracture group. Crista formation and angulation were found to be equally frequent in both groups. The findings are discussed.
Metastatic tumours of the temporal bone
Authors: Belal A. 
Published: November 2007

AbstractMetastatic tumours of the temporal bone seem to be more common than is recognized. Most of these tumours are microscopic and asymptomatic in nature. Microscopic examination of 22 temporal bones belonging to 13 cases of metastatic tumours is reported. The commonest site of involvement in the temporal bone was the petrous apex followed by the tegmen tympani, mastoid bone and internal auditory canal. Primary tumours were most commonly located in the breast. Other sites of primary tumours included the thyroid gland, brain, lungs, prostate and blood (leukaemia). Two cases had undetermined sites of origin. Full neurotologic evaluation is indicated in every case suspected of having a temporal bone metastasis. All three modalities (of surgery, radiotherapy and chemotherapy) are used in combination for the treatment of these tumours.
Tuberculous laryngitis—a one year harvest
Authors: Gertler R. , Ramages L. 
Published: November 2007

AbstractWe present nine patients with tuberculous laryngitis seen in our otolaryngology out-patient department during the year of 1983. Four patients were previously diagnosed as having pulmonary tuberculosis and were receiving or had received treatment for the complaint prior to our consultation. Of the nine patients, eight had positive chest X-rays for pulmonary tuberculosis. Three patients were known to have positive sputum results; in three patients the result was not known, whilst in the remaining three patients the result was recorded as negative. Biopsies done on four patients were compatible with the diagnosis of tuberculous laryngitis. Two of these four were undisputedly confirmed by the presence of Acid-fast Bacilli on histological sections. Two patients demonstrated permanent structural derangement of the larynx as end-result manifestations. The incidence, site and appearance of the lesions, diagnosis and treatment are discussed.
Multiple acinic cell carcinoma
Authors: Gustafsson H. , Carlsöö B. 
Published: November 2007

AbstractA case is presented of multiple acinic cell carcinoma, occurring synchronously in the left parotid gland and in the right submaxillary gland of a 75-year-old male patient. Fourteen cases of primary multiple acinic cell carcinoma have previously been reported, all bilateral parotid gland tumours. To our knowledge this is the first report of extraparotid localization of an acinic cell carcinoma in a patient presenting multiple salivary gland tumours. The histologic and ultrastructural characteristics of the tumours are described and a review of the literature is given.
Surgical salvage in postcricoid cancer
Authors: Jones P. H. , Farrington W. T. , Weighill J. S. 
Published: November 2007

SummaryTwenty-one total pharyngo-laryngectomies have been performed at the Manchester Royal Infirmary between 1968 and 1982. A variety of methods of repair have been used, gastric transposition being the most common. Seventeen patients had received previous radiotherapy to the area, fourteen radical, two palliative and one to a supraglottic carcinoma 12 years before. Four had tumours judged to be too large to benefit from radiotherapy.Of the patients who received radiotherapy, fourteen had a good response with palliation for an average of ten months before symptoms began to return.Four patients survived over five years post-operatively and ten died following surgery.
The use of free tissue transfer in reconstruction following head and neck tumour resection
Authors: Framption M. C. , Breach N. M. , Archer D. J. , Shaw H. J. 
Published: November 2007

AbstractForty four free vascularised tissue flaps have been used in the reconstruction of defects arising following the treatment of malignant disease of the head and neck in 42 patients over the period January 1983 to September 1984. The uses of free flaps and their advantages and disadvantages when compared with other methods of reconstruction are described.
Salivary duct adenocarcinoma: a high grade malignancy
Authors: Hui Kathleen K. , Batsakis John G. , Luna Mario A. , MacKay Bruce , Byers Robert M. 
Published: November 2007

AbstractSalivary duct carcinomas of the major salivary glands have two major distinguishing features. They closely resemble ductal carcinomas of the breast and they are high-grade malignancies. In general, but particularly for carcinomas measuring three or more centimeters in size, the clinical course is one characterized by a resistance to local control, metastases to regional lymph nodes and distant sites, and death within a few years after primary surgical treatment.
Oral-pharyngeal histoplasmosis
Authors: Sooknundun Mukhesh , Kacker S. K. , Kapila K. 
Published: November 2007

AbstractHistoplasmosis is a rare disease in India. We are reporting this disease in a middle-aged non-Caucasian male who has never travelled outside India. Successful treatment was achieved with the nephrotoxic anti-mycotic drug (Amphotericin B), despite a pre-existing renal impairment.
Tracheo-oesophageal ‘Puncture Speech’
Authors: Cheesman A. D. , Knjight J. , McIvor J. , Perry A. 
Published: November 2007

AbstractWe describe the assessment procedures used at Charing-Cross Hospital to investigate laryngectomees who failed to develop oesophageal voice and give the results of assessment in 50 patients. Anatomical or physiological abnormalities in the reconstructed pharynx were found in all patients, and we feel these significantly contributed to the failure of achieving an oesophageal voice. The four cases of failure were due to hypotonicity of the pharyngo-oesophageal muscles, hypertonicity, frank spasm and stricture. This distinction can be used as a functional classification of failure as treatment for each group has to be different if successful surgical voice restoration is to be achieved. Patients with hypotonicity need to use external pressure; those with mild hypertonicity are able to use a low pressure tracheo-oesophageal voice prosthesis; those with spasm need a pharyngo-oesophageal myotomy prior to “puncture”, while those with stricture need surgical correction.
The caloric response in the contralateral ear in acoustic neuroma
Authors: Kirtane M. V. , Merchant S. N. , Medikeri S. B. 
Published: November 2007

AbstractThe caloric test response from the unaffected ear in a case of acoustic neuroma may be normal, hypoactive or hyperactive; each has a different pathophysiological connotation: a normal response is the anticipated finding; a hyperactive contralateral response is due to the presence of a large neuroma with brainstem compression; and a hypoactive response may result from several factors, such as lack of mental alertness during the test, drugs like barbiturates, raised intracranial tension, or the presence of bilateral neuromas.
Vascular effects of topical oxymetazoline on human nasal mucosa
Authors: Bende M. , Löth S. 
Published: November 2007

AbstractOxymetazoline, a derivative of imidazoline, is a widely used nasal decongestant. In contrast to other topical decongestants related to phenylephrine, sympathomimetic amines, it also induced a reduced nasal mucosal blood flow. The purpose of the present investigation was to evaluate the duration of effect of oxymetazoline on nasal airway resistance and mucosal blood flow. During the eight hours of study, the blood flow was reduced by 30–40 per cent in six hours. A similar decongestant effect of about 30 per cent was found during the same interval. The pharmacological profile of oxymetazoline seems questionable, since a reduced nasal mucosal blood flow might not be of value in the treatment of upper airways infections.
Incidence of squamous cell carcinoma of the head and neck: Report of 1,000 cases
Authors: Ali Shaukat , Tiwari Rammohan , Snow Gordon B. , Waal I. V.D. 
Published: November 2007

AbstractThe purpose of this paper is to define the incidence of squamous cell carcinoma (SCC) of the head and neck as seen at the Free University Hospital, Amsterdam, the Netherlands, in the last six years, according to the latest revised classification system of the International Union against Cancer (UICC, 1982). In addition, male to female ratios, relative frequencies at the various sites, age distribution, incidence of second or third primary and the relationship of distant metastases to the nodal metastases and the T-stage of the primary lesion are reported. These incidences are compared with those in other countries and the major differences are discussed.
Effect of denervation on primate laryngeal muscles: a morphologic and morphometric study
Authors: Sahgal V. , Hast M. H. 
Published: November 2007

AbstractPrimate intrinsic laryngeal muscles studied consisted of Type I and Type II fibres. Type II fibres were larger than Type I fibres. The coefficient of variance of these muscles suggested that the fibre-size variation was similar in all of these muscles. Denervation resulted in shrinking of Type II fibres at two weeks in all the muscles, while at four weeks the thyroarytenoid showed an inflammatory reaction and far greater reduction in size than the other muscles. At eight weeks, however, all the muscles were fibrosed. We conclude that laryngeal muscles begin to show evidence of denervation at two weeks and are fibrosed in eight weeks. The thyroarytenoid muscle showed inflammatory degeneration, while the posterior cricoarytenoid and cricothyroid muscles showed classical changes of denervation. These findings should have clinical significance in the timing of reinnervation procedures.
Rhabdomyoma of the larynx
Authors: Rosenman D. , Gertner R. , Fradis M. , Podoshin L. , Misslevitsch A. , Boss J. H. 
Published: November 2007

AbstractSince 1897 a total of 37 cases of extracardiac rhabdomyomas of the fetal type have been reported in the literature. Only two of these were localized in the larynx. We report an additional case of extracardiac rhabdomyoma localized in the larynx, and the pertinent literature is discussed. Although rare, its existence should be kept in mind in the differential diagnosis of laryngeal tumours.
Cartilaginous neoplasms of the head and neck
Authors: Webber P. A. , Hussain S. S. M. , Radcliffe G. J. 
Published: November 2007

AbstractThe presenting features and management of three cases of chondroma and one of chondrosarcoma in different head and neck sites are described. The rarity of this tumour is emphasized by a brief review of the literature. The fact that all the above cases presented within two years to one District General Hospital makes this series very unusual indeed.
Skeletal lesions in von Recklinghausen's disease of the head and neck in Nigerian Africans
Authors: Ijaduola G. T. A. , Ademiluyi S. A. , Olarenwaju D. A. 
Published: November 2007

SummaryA study of skeletal lesions in the head and neck region of 20 adult patients with von Recklinghausen's disease, seen in the Surgical Out Patient clinic of Lagos University Teaching Hospital from 1979 to 1985, has been carried out. Among the 20 patients, 13 (65 per cent) had symptoms related to the head and neck while 7 (37 per cent) did not; however, on radiological screening, all of them were observed to have skeletal lesions. The commonest feature was enlarged intervertebral nerve root exit foramina from mesodermal dysplasia, which occurred in 16 (80 per cent) of our patients. Other major findings were erosion of the mandible, 8 (40 per cent); erosion of the wings of the sphenoid, 4 (20 per cent); poor mastoid bone pneu-matisation, 3 (15 per cent); erosion of the parietal bone, 3 (15 per cent) and heterotopic bone formation, 1 (5 per cent). Congenital calvarial defects were not detected. In view of the fact that all our patients showed radiologically detectable skeletal lesions of the head and neck, despite absence of symptoms in 35 per cent, it is advisable that all patients with von Recklinghausen's disease should routinely have radiological screening of this region, to detect early lesions.
Localisation of a CSF fistula by metrizamide CT cisternography
Authors: Luotonen J. , Jokinen K. , Laitinen J. 
Published: November 2007

AbstractLocalisation of a cerebrospinal fluid fistula in the nasal region is difficult. Lack of a suitable roentgen contrast medium for intrathecal use has earlier restricted theutility of cisternography. Metrizamide cisternography and CT have recently proved to be well tolerated and effective in revealing CSF fistulae. A case report of operatively treated CSF rhinorrhea recurring after three years is presented. With the help of CT metrizamide cisternography, the fistula could finally be localised in the sphenoidal sinus. The re-operation confirmed this finding. The technique of cisternography is described.
Dysequilibrium of ageing (presbyastasis)
Authors: Belal A. , Glorig Aram 
Published: November 2007

AbstractWe reviewed clinical findings in 740 patients over age 65 who consulted the Otological Medical Group, Inc., during a one-year period for dizziness. A thorough neurotologic evaluation is indicated in every such case to determine the specific cause of dizziness. In 21 per cent of these patients, a specific cause of dizziness was found. In the remaining 79 per cent, the diagnosis of primary dysequilibrium of ageing (presbyastasis) was made.We classified dysequilibrium of ageing (presbyastasis) according to the character, time course, and precipitating factors of dizziness. Two clinical types were described: constant and unclassified. The histological finding in the temporal bones of four cases with dysequilibrium of ageing were reviewed. Pathological changes other than those in the peripheral vestibular system seem to be responsible for dysequilibrium of ageing.In the present series, about three-fourths of the patients had a daily dose of nicotinic acid to produce flushing of the skin. In 16 per cent, the dizziness was minor, requiring no special treatment. In the remaining 9 per cent with incapacitating vertigo, a vasodilator regimen, antivertiginous drugs, and Cawthorne's vestibular exercises were prescribed.
Efficacy of medical treatment as an adjunct to surgery in the treatment of secretory otitis media
Authors: Lesser T. H. J. , Clayton M. I. , Skinner D. 
Published: November 2007

AbstractIn a pilot controlled randomised trial of 38 children who had bilateral secretory otitis media, with effusion demonstrated at operation, we compared the efficacy of a six-week course of an oral decongestant—antihistamine combination and a mucolytic preparation with a control group in preventing the presence of middle-ear effusion six weeks after myringotomy and adenoidectomy. The mucolytic preparation decreased the presence of middle-ear effusion when compared to the decongestant-antihistamine combination and the control group (p=0.06).
Crosslinks between stereocilia in hair cells of the human and guinea pig vestibular labyrinth
Authors: Jeffries David J. , Pickles James O. , Osborne Michael P. , Rhys-Evans Peter H. , Comis Spiro D. 
Published: November 2007

AbstractThe saccules and ampullae of the semicircular canals from human and guinea pig temporal bones were fixed in glutaraldehyde without osmium. Crosslinks were seen between stereocilia of the vestibular hair cells, similar to those previously demonstrated in the guinea pig, although an additional set of crosslinks was displayed: first, horizontal crosslinks were seen between adjacent stereocilia, occupying most of the length of the hair bundle; secondly, a single upward-pointing link ran from the apex of each shorter stereocilium into the shaft of the adjacent taller ster-eocilium; thirdly, an extensive array of horizontal links were demonstrated between stereocilia close to their insertion into the cuticular plate. We suggest that these basal crosslinks support the long vestibular stereocilia rendering them more rigid, and that the upwind pointing crosslinks are responsible for the initiation of sensory transduction.
Surgical anatomy of the round window with special reference to cochlear implantation
Authors: Franz Burkhard K. H. , Clark Graeme M. , Bloom David M. 
Published: November 2007

AbstractWhen the multi-channel cochlear implant electrode is inserted into the scala tympani through the round window the operation is best performed via a posterior tympanotomy. The view of the round window membrane, however, is incomplete because of its orientation and the fact that it has a conical shape. Nevertheless, a good view along the basal turn is obtained after the antero-inferior overhang of the round window niche and the crista fenestrae have been removed. It might be damaging to drill away the postero-superior overhang as the osseous spiral lamina lies extremely close to the round window membrane.
Prevalence of secretory otitius media among school children in Kuwait
Authors: Holmquist Jörgen , Al Fadala Sanad , Qattan Yaccob 
Published: November 2007

AbstractTympanometry and otoscopy were performed by the authors on 893 schoolchildren in Kuwait during early 1983. Based on tympanometry 31.3 per cent were found to have tympanograms indicating secretory otitis media. The otoscopic findings confirmed this high prevalence (30.0 per cent). At re-examination three months later, the point prevalence had decreased by almost 5 per cent which is well in accordance with the seasonal variation of this disease.
The nasal distribution of metered does inhalers
Authors: Newman S. P. , Morén F. , Clarke S. W. 
Published: November 2007

AbstractThe intranasal distribution of aerosol from a metered dose inhaler has been assessed using a radiotracer technique. Inhalers were prepared by adding 99Tcm-labelled Teflon particles (simulating the drug particles) to chlorofluorocarbon propellants, and scans of the head (and chest) taken with a gamma camera. Ten healthy subjects (age range 19–29 years) each performed two radioaerosol studies with the inhaler held in two different ways: either in a single position (vial pointing upwards) or in two positions (vial pointing upwards and then tilted by 30° in the sagittal plane).The vast majority of the dose (82.5 ± 2.8 (mean ± SEM) per cent and 80.7 ± 3.1 per cent respectively for one-position and two-position studies) was deposited on a single localized area in the anterior one-third of the nose, the initial distribution pattern being identical for each study. No significant radioaerosol was detected in the lungs. Only 18.0 ± 4.7 per cent and 15.4 ± 4.1 per cent of the dose had been removed by mucociliary action after 30 minutes, and it is probable that the remainder had not penetrated initially beyond the vestibule. Since the deposition pattern was highly localized and more than half the dose probably failed to reach the turbinates it is possible that the overall effect of nasal MDIs is suboptimal for the treatment of generalized nasal disorders.
Fibrin glue in nasal septal surgery
Authors: Hayward P. J. , Mackay I. S. 
Published: November 2007

AbstractWe have successfully used fibrin glue to avoid operative nasal packing in 30 cases of septal surgery. Avoiding a nasal pack is not only more acceptable to the patient but may also reduce hospital stay. Analysis of our results showed some minor short-term complications but initial post-operative septal deviation tended to resolve spontaneously. Transient oedema and hyperaemia occurred in 37 per cent of cases and may represent an allergic response despite few classical allergic reactions having been reported.
Who should treat epistaxis?
Authors: John D. G. , Alison A. I. , Scott D. J. A. , McRae A. R. , Allen M. J. 
Published: November 2007

AbstractA prospective study was undertaken of 75 patients complaining of epistaxis who presented to an Accident and Emergency Department.The patients were placed into four groups according to their presenting features, and various forms of appropriate management applied.It was found that in the group that had ceased bleeding on presentation, whether or not a bleeding point was visible, there was no benefit obtained by treatment. If the nose was still bleeding on presentation, and the bleeding point was visible, successful management could be obtained by cauterising the bleeding point. This is a treatment that could be carried out by either the General Practitioner or the Accident Department. If the nose was actively bleeding, and the bleeding point could not be seen, then even initially successful treatment by the Accident Department was usually found to be ineffective within forty-eight hours. It is suggested that this group should be referred to an ENT unit on presentation.