bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Rhône-Alpes Health Platform
Authors: Durand T. , Spacagna H. , Biron P. , Flory A. , Verdier C. 
Published: September 2007

Summary

Objectives:
The purpose of this workis to develop a health information platform connecting most health facilities in the Rhône-Alpes region. The health platform called SIS-RA is used through a Web interface. An iconic interface is dedicated to the platform and presents information in a unique way for all users.

Methods:
Newtechniques have been used to develop this platform which will be used by a great number of Rhône-Alpes doctors in the future. We chose a user-centered design which takes into account doctors’ requirements (hospital and GP). We also consider that no system has to be rebuilt, but a direct connection to the legacysystems should be provided.

Results:
The platform permits fast and more appropriate medical decisions than those made without this information system. The iconic interface presents all medical documents in a uniform way. Currently, 11 healthcare facilities and 15 community health networks are connected to SIS-RA sharing more than 60,000 records with 1.2 million indexed items. 3200 doctors use the system.

Conclusion:
The platform is approved by French supervision authorities (regional hospitals association (ARH)), regional practitioners union (URML) and Rhônes-Alpes region administration and is known as the official shared health record.
Clinical Pathways in General Surgery
Authors: Richter S. , Folz J. , Pham P.-T. , Jacob P. , Schilling M. K. , Graeber S. 
Published: September 2007

Summary

Objectives:
To emphasize the importance of the view of business process management for development and implementation of clinical pathways, and to evaluate their effectiveness in reducing cost and effort as well as enhancing patient satisfaction.

Methods:
We describe the development and implementation of pathways with methods of process management and the design and realization of an evaluation study in the setting of a surgical department. For this study 67 patients treated without clinical pathways were compared with 62 patients treated using pathways.

Results:
The approach explicitly enhances the development and implementation of clinical pathways. The introduction of pathways reduces length of hospital stay, number of laboratory tests, number of consultations, and number of imaging procedures. Patient satisfaction is improved.

Conclusions:
Depending on design and setting, the introduction of clinical pathways may be a very promising method to improve the inpatient service at a hospital and so to react to the challenges of increasing competition in medical care.
Experiences with an Interoperable Data Acquisition Platform for Multi-centric Research Networks Based on HL7 CDA
Authors: Prokosch H.-U. , Müller M. , Ganslandt T. , Klein A. 
Published: September 2007

Summary

Objectives:
Today’s increasing specialization of medicine necessitates the integration oftelematic platforms for cross-institutional cooperation. In orderto leverage the strengths of each cooperating institution a centralized unified storage using shared electronic patient records (EPRs) as well as secured remote data entry capabilities for supporting collaborative clinical research and care is essential. The objective of this project was to develop and introduce into routine use such a shared remote data entry (RDE) platform for the German multicentric Epidermolysis Bullosa (EB) network.

Methods:
An existing telematic application was extended by a remote data entry (RDE) module enabling thestorage of structured data and pedigrees. HL7 Clinical Document Architecture (CDA) was chosen as a suitable standardized storage format that provides flexibility and future interoperability. Flexible data entry forms adaptable to distinct medical domains were implemented using XML-based technologies.

Results:
A flexible and comprehensive ePR/RDE platform was successfully implemented in the German EB network. A set of specific data entry forms was created to fully cover the network’s documentation needs. The platform has been in productive use since 2005.

Conclusions:
Standardized documentation by using HL7 CDA to store the medical research data as an EPR can contribute to high interoperability and an easier integration of heterogeneous health care information systems. Existing XML technologies offer a high degree of flexibility and adaptability to distinct medical domains. The ongoing development of standards (e.g. HL7 CDA R2) and interfaces (CDA/CDISC bridge) could further improve semantic and syntactic interoperability.
Integrated Information Systems for Translational Medicine
Authors: Funkat G. , Haeber A. , Mauz-Koerholz C. , Pommerening K. , Smers S. , Stausberg J. , Winter A. 
Published: September 2007

Summary

Objectives:
Translational medicine research needs a two-way information highway between ‘bedside’ and ‘bench’. Unfortunately there are still weak links between successfully integrated information roads for bench, i.e. research networks, and bedside, i.e. regional or national health information systems. The question arises, what measures have to be taken to overcome the deficiencies.

Methods:
It is examined how patient care-related costs of clinical research can be separated and shared by health insurances, whether quality of patient care data is sufficient for research, how patient identity can be maintained without conflict to privacy, how care and research records can be archived, and how information systems for care and research can be integrated.

Results:
Since clinical trials improve quality of care, insurers share parts of the costs. Quality of care data has to be improved by introducing minimum basic data sets. Pseudonymization solves the conflict between needs for patient identity and privacy. Archiving patient care records and research records is similar and XML and CDISC can be used. Principles of networking infrastructures for care and research still differ. They have to be bridged first and harmonized later.

Conclusions:
To link information systems for care (bed) and for research (bench) needs technical infrastructures as well as economic and organizational regulations.
Development and Implementation of an Analysis Tool for Array-based Comparative Genomic Hybridization
Authors: Rosolowski M. , Berger H. , Schwaenen C. , Wessendorf S. , Loeffler M. , Hasenclever D. , Kreuz M. 
Published: September 2007

Summary

Objectives:
Array-comparative genomic hybridization (aCGH) is a high-throughput method to detect and map copy number aberrations in the genome. Multi-step analysis of high-dimensional data requires an integrated suite of bioinformatic tools. In this paperwe detail an analysis pipeline for array CGH data.

Methods:
We developed an analysis tool for array CGH data which supports single and multi-chip analyses as well as combined analyses with paired mRNA gene expression data. The functions supporting relevant steps of analysis were implemented using the open source software R and combined as package aCGHPipeline. Analysis methods were illustrated using 189 CGH arrays of aggressive B-cell lymphomas.

Results:
The package covers data input, quality control, normalization, segmentation and classification. For multi-chip analysis aCGHPipeline offers an algorithm for automatic delineation of recurrent regions. This task was performed manuallyup to now. The package also supports combined analysis with mRNA gene expression data. Outputs consist of HTML documents to facilitate communication with clinical partners.

Conclusions:
The R package aCGHPipeline supports basic tasks of single and multi-chip analysis of array CGH data.
Fluorine-containing Diethynyl Aryl Derivatives for n-Channel Organic Field-effect Transistors
Authors: Kashiwagi Kimiaki , Yasuda Takeshi , Tsutsui Tetsuo 
Published: September 2007

Abstract
Fluorine-containing diethynyl aryl derivatives (1–5), in which three aromatic rings were connected together with rigid acetylenic linkages, were synthesized for n-channel organic field-effect transistors. The field-effect electron mobility of the thin film of 2 exhibited 3.4×10−3 cm2 V−1 s−1.
Dual Polyrotaxane: One-pot Synthesis of Topological Polymer by Using Metathesis Reaction
Authors: Yamabuki Kazuhiro , Isobe Yukio , Onimura Kenjiro , Oishi Tsutomu 
Published: September 2007

Abstract
The topological polyrotaxane was built from an ammonium salt as an axle component bearing one olefin and one bulky unit at the end of chain and the derivative of dibenzo-24-crown-8 (DB24C8) as a wheel component having one terminal olefin. In this system, two kinds of reactions work at the same time as a driving force of the polymer construction. One is the inclusion reaction between the ammonium salt part of axle and the wheel, another is metathesis reaction between olefins of the axle and olefins of the wheel.
Two Limonoids from the Root of Dictamnus radicis Cortex
Authors: Zhao Pei-Hua , Sun Li-Mei , Cao Mei-Ai , Yuan Cheng-Shan 
Published: September 2007

Abstract
A new limonoid isodictamdiol (1) and a known dictamdiol (2), the first 5S/9S-type degraded limonoids, were isolated from the EtOAc extracts of Dictamnus radicis Cortex. The structures of compounds 1 and 2 were respectively elucidated by means of the modern spectroscopic methods, including IR, MS, NMR, a single-crystal X-ray diffraction, as well as CD. In addition, the absolute configuration of 2 was determined for the first time.
Nano Bowls of Carbon by Oxidative Chopping of Carbon Nano Sphere
Authors: Abdi Sayed Hasan Razi , Kim Young Jin , Park Yong-Ki , Lee Chul Wee 
Published: September 2007

Abstract
Here, we report the preparation of novel carbon material having fairly uniform bowl shape in nanosize domain with varying oxygen content by a very simple oxidative chopping of carbon nanoballs, where we have effectively functionalized the inert CNS (carbon nano sphere) with carboxylate groups that can be utilized for the chemical immobilization of enzymes, bioactive compounds, and catalysts.
Viscoelastic Behavior of Thermoresponsive Polymer Hydrogel with Organic Adsorbate Observed Using Quartz Crystal Microbalance
Authors: Nakano Yuri , Sato Itaru , Seida Yoshimi , Nakano Yoshio 
Published: September 2007

Abstract
Thermoresponsive viscoelastic behavior of poly(N-isopropylacrylamide) (PNIPA) hydrogel was investigated using quartz crystal microbalance (QCM) with the impedance analysis as a function of temperature and concentration of benzoic acid (BA) that adsorbs onto the gel. The viscoelastic behavior of gel in its shrinking phase was observed with high resolution. The adsorption of benzoic acid affected the viscoelasticity in the shrinking phase significantly over the wide range of concentration of BA.
Synthesis and Luminescent Properties of Two Copolymers Containing Dithienothiophene and Fluorene
Authors: Song Yinyin , Zhang Wenyu , Zhang Wei , Li Jun , Li Suyue , Zhou Huiqiong , Qin Jingui 
Published: September 2007

Abstract
Two new copolymers, poly[fluorene-co-α-dithieno[3,2-b:2′,3′-d]thiophene] (PFDTT-α) and poly[fluorene-co-β-dithieno[3,2-b:2′,3′-d]thiophene] (PFDTT-β) were synthesized through the Suzuki coupling reaction, where dithieno[3,2-b:2′,3′-d]thiophene (DTT) was introduced into the backbones of polyfluorenes by two different linkage styles, which distinctively tuned HOMO/LUMO levels of the copolymers and the effective conjugation length.
Imaging of Aromatic Amide Molecules in Motion
Authors: Solin Niclas , Koshino Masanori , Tanaka Takatsugu , Takenaga Shinya , Kataura Hiromichi , Isobe Hiroyuki , Nakamura Eiichi 
Published: September 2007

Abstract
Visual evidence of the rotation of an amide group has been obtained by transmission electron microscope (TEM) observation of aromatic amide molecules encapsulated in a carbon nanotube. The fullerene group used as a tag also acts as an anchor to fix the sample molecule in one position, which made possible the observation of the rotation of the amide and the pyrene groups.
Was there compression of disability for older Americans from 1992 to 2003?
Authors: Cai Liming , Lubitz James 
Published: September 2007

Abstract
Medical advances and the growth of the elderly population have focused interest on trends in the health of the elderly. Three theories have been advanced to describe these trends: compression of morbidity, expansion of morbidity, and dynamic equilibrium. We applied multistate life table methods to the Medicare Current Beneficiary Survey to estimate active and disabled life expectancy from 1992 to 2003, defining disability as having difficulty with instrumental activities of daily living or activities of daily living. We found increases in active life expectancy past age 65 and decreases in life expectancy with severe disability. These trends are consistent with elements of both the theory of compression of morbidity and the theory of dynamic equilibrium.
Multipartnered fertility among American men
Authors: Guzzo Karen Benjamin , Furstenberg Frank F. 
Published: September 2007

Abstract
Using the 2002 (Cycle 6) National Survey of Family Growth (NSFG), which was the first NSFG to interview men, we document the prevalence and correlates of sequential parenthood with different partners (multipartnered fertility) among a representative sample of American men. Nearly 8% of American men aged 15–44 report having had children with more than one partner, with sharp differences by age, race/ethnicity, and income—over one-third of poor black men aged 35–44 report having had children with two or more mothers, and 16% report children with three or more mothers. Fathers of two or more children by multiple partners appear to be more disadvantaged than fathers with two or more children by the same partner. Multipartnered fertility is strongly related to prior birth characteristics; men not in a coresidential union at the preceding birth are more likely to have their next birth with a new partner, and controlling for prior-birth characteristics accounts for the elevated risk of Hispanics and blacks in baseline models. Results also suggest that multipartnered fertility is becoming more prevalent as younger cohorts transition to a new-partner birth more quickly and at a higher rate than older cohorts.
Paradox found (again): Infant mortality among the Mexican-origin population in the united states
Authors: Hummer Robert A. , Powers Daniel A. , Pullum Starling G. , Gossman Ginger L. , Frisbie W. Parker 
Published: September 2007

Abstract
Recent research suggests that the favorable mortality outcomes for the Mexican immigrant population in the United States may largely be attributable to selective out-migration among Mexican immigrants, resulting in artificially low recorded death rates for the Mexican-origin population. In this paper, we calculate detailed age-specific infant mortality rates by maternal race/ethnicity and nativity for two important reasons: (1) it is extremely unlikely that women of Mexican origin would migrate to Mexico with newborn babies, especially if the infants were only a few hours or a few days old; and (2) more than 50% of all infant deaths in the United States occur during the first week of life, when the chances of out-migration are very small. We use concatenated data from the U.S. linked birth and infant death cohort files from 1995 to 2000, which provides us with over 20 million births and more than 150,000 infant deaths to analyze. Our results clearly show that first-hour, first-day, and first-week mortality rates among infants born in the United States to Mexican immigrant women are about 10% lower than those experienced by infants of non-Hispanic, white U.S.-born women. It is extremely unlikely that such favorable rates are artificially caused by the out-migration of Mexican-origin women and infants, as we demonstrate with a simulation exercise. Further, infants born to U.S.-born Mexican American women exhibit rates of mortality that are statistically equal to those of non-Hispanic white women during the first weeks of life and fare considerably better than infants born to non-Hispanic black women, with whom they share similar socioeconomic profiles. These patterns are all consistent with the definition of the epidemiologic paradox as originally proposed by Markides and Coreil (1986).
Contraceptive use patterns across teens’ sexual relationships: The role of relationships, partners, and sexual histories
Authors: Manlove Jennifer , Ryan Suzanne , Franzetta Kerry 
Published: September 2007

AbstractBy using data from the National Longitudinal Study of Adolescent Health, we examine how adolescent relationship characteristics, partner attributes, and sexual relationship histories are associated with contraceptive use and consistency, incorporating random effects to control for respondent-level unobserved heterogeneity. Analyses show that teens’ contraceptive use patterns vary across relationships. Teens with more-homogamous partners, with more-intimate relationships, and who communicate about contraception before sex have greater odds of contraceptive use and/or consistency. Teens in romantic relationships, and who are older when engaging in sex for the first time, have greater odds of ever using contraceptives but reduced odds of always using contraceptives. Teens continue habits from previous relationships: teens with experience practicing contraceptive consistency and females who previously have used hormonal contraceptive methods are better able to maintain consistency in subsequent relationships. Also, relationship and partner characteristics are less important for females who previously used hormonal methods.
Maladaptive Beliefs and Suppression of Negative Autobiographical Memories
Authors: Broadbent James C. , Nixon Reginald D.V. 
Published: September 2007

AbstractThis study sought to investigate whether an individual difference in beliefs regarding the importance of controlling intrusive thoughts influenced the effect of suppressing negative autobiographical memories. In Phase I of the study, 165 undergraduate students completed the control-subscale of the Interpretations of Intrusions Inventory (III-31). Students with scores in the top (strong beliefs) and bottom (weak beliefs) 30% of the III-31 were selected to participate in Phase II. In Phase II an equal number of students with these ‘strong’ and ‘weak’ beliefs (N = 60) were randomised to either a thought suppression or control condition. As expected, instructions to suppress resulted in a rebound effect; however, contrary to predictions, differences in beliefs regarding the importance of controlling intrusive thoughts did not influence thought suppression ability. The implications of the findings for understanding the influence of metacognition on thought suppression are discussed.
Functional Communication and Other Concomitant Behavior Change Following PECS Training: A Case Study
Authors: Anderson Angelika , Moore Dennis W. , Bourne Therese 
Published: September 2007

AbstractThe Picture Exchange Communication System (PECS) is widely used to teach children with language delays, including those with autism, functional language. A feature of PECS is that it incorporates principles deemed by some to be pivotal, leading to broader behaviour change. In this study, a 6-year-old child with autism was taught functional language using PECS. Along with measures of language gains, concomitant changes in nontargeted behaviours (play and TV viewing) following PECS training were observed. Results show increases in manding, initiations and cumulative word counts, as well as positive changes in the nontargeted behaviours.
Influences on the Stages and Processes of Exercise Adoption in Women
Authors: Girling-Butcher Robyn , Towers Andy , Flett Ross , Seebeck Renée 
Published: September 2007

AbstractThe present study investigated the transtheoretical model of behaviour change in relation to exercise adoption and maintenance in a sample of 140 women. The aim was to examine the relationship between the stages of exercise change, and the constructs of processes of change, costs and benefits of exercising, self-efficacy, and self-rated health. Analyses revealed that the processes, pros, cons, self-efficacy, and self-rated health were significantly associated with stage of exercise adoption. Specifically, the processes fluctuated, pros and self-efficacy increased, and cons decreased across the stages from precontemplation to maintenance. A stage exercise adoption perspective may be particularly useful for understanding how women adopt and sustain exercise regimes.
Family Needs After Traumatic Brain Injury: Implications for Rehabilitation Counselling
Authors: Bishop Malachy , Degeneffe Charles Edmund , Mast Melinda 
Published: September 2007

AbstractFamily involvement in the rehabilitation counselling process is increasingly being recognised as an important component of rehabilitation success. This may be particularly true for persons who have an acquired or traumatic brain injury (TBI). For such individuals the emotional and psychosocial functioning of their family and caregivers has been associated with a variety of functional, psychosocial, and employment outcomes. Addressing the needs of family members is an important component of providing effective rehabilitation counselling services, but one that has received little attention in the rehabilitation counselling literature. This article reviews current research on the frequently identified needs of families and caregivers of persons with TBI, the family and situational variables that have been explored for their relationship to family needs, and the extent to which these needs are met. Clinical and research implications for rehabilitation counsellors are identified.
Evolution and Sustainability of the Helping Hands Volunteer Program: Consumer Recovery and Mental Health Comparisons Six Years On
Authors: Deane Frank P. , Andresen Retta 
Published: September 2007

AbstractThe Helping Hands program commenced in 1999 and partners volunteers with mental health consumers for support and to increase social contact, recreational and friendship opportunities. The aim of the present study is to describe the evolution and sustainability of the program over the first 6 years. A description of consumers accessing the program using recovery-oriented measures and traditional measures of behavioural functioning is also provided. Service data was collected on the development of the program, service utilisation, volunteer participation and funding patterns. Cross-sectional measures of recovery and baseline and follow-up Health of the Nation Outcome Scales (HoNOS) were collected on 27 participants. Results showed that the Helping Hands program has evolved significantly since start-up with the development of numerous recreational, health and support groups and 48 active volunteers and 62 active clients. Consumer feedback indicates that the service increases the quality of life of participants considerably. Current clients showed less severe disability at referral than did the original group. There were improvements in the area of relationships on the HoNOS for those who had baseline and follow-up measures. The high volunteer participation rates and positive consumer outcomes represent significant value in return for the modest level of funding.
Environmental tritium measurements and lumped parameter modelling in the Tafilalet aquifer, south-east Morocco
Authors: Bouhlassa S. , Ammary B. , Elyahyaoui A. 
Published: September 2007

The paper presents a case study for the application of environmental tritium to assess the mean residence time of water in the Tafilalet aquifer. This aquifer corresponds geologically to a tectonic depression with Quaternary fill. The Tafilalet area depends mainly on agriculture and herding. Groundwater is the main source of water supply for domestic, agriculture, and herding purposes.
The data on the distribution of tritium in subsurface water indicate the modern water of the Tafilalet aquifer. The tritium transport modelling indicates that Quaternary alluvial waters are likely to have short mean residence times of a few years (14 to 32 years). The study addresses several difficulties concerning the detailed quantitative interpretations of the results, which must be the focus of future work.