bluuebunny/crossref_metadata_2025_split huggingface dataset:
Electronically Tunable Compact Trialkylphosphines: SMAPs‐Bridged Bicyclic Phosphines.
Authors: Ochida Atsuko , Ito Shinichiro , Miyahara Takahiro , Ito Hajime , Sawamura Masaya 
Published: August 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Practical Synthesis of Chiral Vinylphosphine Oxides by Direct Nucleophilic Substitution. Stereodivergent Synthesis of Aminophosphine Ligands.
Authors: Oliana Marco , King Frank , Horton Peter N. , Hursthouse M. B. , Hii King Kuok 
Published: August 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
An Efficient Method for the Esterification of Phosphonic and Phosphoric Acids Using Silica Chloride.
Authors: Sathe Manisha , Gupta Arvind K. , Kaushik M. P. 
Published: August 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Titanium(IV) Chloride Complexes with Chiral Tetraaryl‐1,3‐dioxolane‐4,5‐dimethanol Ligands as a New Type of Catalysts of Ethylene Polymerization.
Authors: Belokon' Yu. N. , Gagieva S. Ch. , Sukhova T. A. , Dmitriev A. B. , Lyssenko K. A. , Bravaya N. M. , Bulychev B. M. , Seebach D. 
Published: August 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Highly Regio‐ and Stereocontrolled Synthesis of β‐Substituted α‐Tributylstannyl Enamides.
Authors: Buissonneaud David , Cintrat Jean‐Christophe 
Published: August 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Sinularectin, a New Diterpenoid from the Soft Coral Sinularia erecta.
Authors: Rudi Amira , Shmul Guy , Benayahu Yehuda , Kashman Yoel 
Published: August 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Sphenadilactones A and B, Two Novel Nortriterpenoids from Schisandra sphenanthera.
Authors: Sun Han‐Dong , et al. et al. 
Published: August 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Sespendole, a New Inhibitor of Lipid Droplet Synthesis in Macrophages, Produced by Pseudobotrytis terrestris FKA‐25
Authors: Uchida Ryuji , Kim Yong‐Pil , Namatame Ichiji , Tomoda Hiroshi , Omura Satoshi 
Published: August 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
A Short and Efficient Synthesis of (.+‐.)‐β‐Cuparenone.
Authors: Kulkarni Mukund G. , Davawala Saryu I. , Shinde Mahadev P. , Dhondge Attrimuni P. , Borhade Ajit S. , Chavhan Sanjay W. , Gaikwad Dnyaneshwar D. 
Published: August 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Studies on the Novel α‐Glucosidase Inhibitory Activity and Structure—Activity Relationships for Andrographolide Analogues.
Authors: Dai Gui‐Fu , Xu Hai‐Wei , Wang Jun‐Feng , Liu Feng‐Wu , Liu Hong‐Min 
Published: August 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
O—N Intramolecular Alkoxycarbonyl Migration of Typical Protective Groups in Hydroxyamino Acids.
Authors: Skwarczynski Mariusz , Sohma Youhei , Noguchi Mayo , Kimura Tooru , Hayashi Yoshio , Kiso Yoshiaki 
Published: August 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Design and Synthesis of Potent Cystine‐Free Cyclic Hexapeptide Agonists at the Human Urotensin Receptor.
Authors: Foister Shane , Taylor Laurie L. , Feng Jin‐Jye , Chen Wen‐Long , Lin Atsui , Cheng Fong‐Chi , Smith Amos B. III , Hirschmann Ralph 
Published: August 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Desulfonylation with Mg—MeOH—NiBr2: An Expedient Reagent System for the Synthesis of 2‐Amino‐2,3‐dideoxy Furanosides.
Authors: Das Indrajit , Pathak Tanmaya 
Published: August 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Novel Glycosylation Reactions Using Glycosyl Thioimidates of N‐Acetylneuraminic Acid as Sialyl Donors.
Authors: Ikeda Kiyoshi , Aizawa Misato , Sato Kazuki , Sato Masayuki 
Published: August 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
A Concise Total Synthesis of Antifungal Antibiotic (+)‐Preussin.
Authors: Gogoi Naminita , Boruwa Joshodeep , Barua Nabin C. 
Published: August 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Formal Total Synthesis of (‐)‐Emetine (IV) Using Catalytic Asymmetric Allylation of Cyclic Imines as a Key Step.
Authors: Itoh Takashi , Miyazaki Michiko , Fukuoka Hiromi , Nagata Kazuhiro , Ohsawa Akio 
Published: August 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Enantiospecific Synthesis of (+)‐Hyacinthacine A2.
Authors: Dewi‐Wuelfing Purnama , Blechert Siegfried 
Published: August 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Synthesis of 7‐Deoxypancratistatin from Carbohydrates by the Use of Olefin Metathesis.
Authors: Haakansson Anders E. , Palmelund Anders , Holm Henriette , Madsen Robert 
Published: August 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
The Structural and Synthetic Implications of the Biosynthesis of the Calycanthaceous Alkaloids, the Communesins, and Nomofungin.
Authors: May Jeremy A. , Stoltz Brian 
Published: August 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Synthesis and RT Inhibitory Activity Evaluation of New Pyrimidine‐Based seco‐Nucleosides.
Authors: Vargas Genaro , Escalona Iker S. , Salas Magali , Gordillo Barbara , Sierra Adolfo 
Published: August 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Synthesis of AZT Analogues: 7‐(3‐Azido‐2‐hydroxypropyl)‐, 7‐(3‐Amino‐2‐hydroxypropyl)‐, 7‐(3‐Triazolyl‐2‐hydroxypropyl)theophyllines.
Authors: El Ashry El Sayed H. , Abdel‐Rahman Adel , Rashed Nagwa , Awad Laila F. , Rasheed Hanaa A. 
Published: August 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
An Efficient Process for Synthesis of 2′‐O‐Methyl and 3′‐O‐Methyl Guanosine from 2‐Aminoadenosine Using Diazomethane and the Catalyst Stannous Chloride.
Authors: Kore Anilkumar R. , Parmar Gaurang , Reddy Srinu 
Published: August 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Synthesis of Novel Nucleoside Analogues Based on 1,3‐Dihydrobenzo[c]furan Core.
Authors: Liu Zhao‐Peng , Meng Zhao‐Li , Wang De‐Feng 
Published: August 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Synthesis of a Potent 5′‐Methylthioadenosine/S‐Adenosylhomocysteine (MTAN) Inhibitors.
Authors: Kamath Vivekanand P. , Zhang Jainwen , Morris Philip E. Jr. , Babu Y. Sudhakar 
Published: August 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Synthesis and Antiproliferative Activity of Two New Tiazofurin Analogues with 2′‐Amido Functionalities.
Authors: Popsavin Mirjana , Torovic Ljilja , Svircev Milos , Kojic Vesna , Bogdanovic Gordana , Popsavin Velimir 
Published: August 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Asymmetric Synthesis of 1,2‐Dioxolane‐3‐acetic Acids: Synthesis and Configurational Assignment of Plakinic Acid A.
Authors: Dai Peng , Trullinger Tony K. , Liu Xuejun , Dussault Patrick H. 
Published: August 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
New Aminophenoxazinones from a Marine Halomonas sp.: Fermentation, Structure Elucidation, and Biological Activity.
Authors: Bitzer Jens , Grosse Thomas , Wang Linzhu , Lang Siegmund , Beil Winfried , Zeeck Axel 
Published: August 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Synthesis of 2‐Methyl 16‐Membered Macrolide Derived from Tylosin.
Authors: Terui Yuichi , Kinoshita Kenji , Kaneda Yoshie , Akashi Toshi , Hamaguchi Takuya , Kawashima Akira 
Published: August 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Total Synthesis of Ageladine A, an Angiogenesis Inhibitor for the Marine Sponge Agelas nakamurai.
Authors: Meketa Matthew L. , Weinreb Steven M. 
Published: August 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Total Synthesis and Confirmation of the Revised Structures of Azaspiracid‐2 (Ia) and Azaspiracid‐3 (Ib).
Authors: Nicolaou K. C. , Frederick Michael O. , Petrovic Goran , Cole Kevin P. , Loizidou Eriketi Z. 
Published: August 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Soft X‐Ray Microscopy of Nanomagnetism
Authors: Fischer Peter , Kim Dong‐Hyun , Chao Weilun , Liddle J. Alexander , Anderson Erik H. , Attwood David T. 
Published: August 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Chemical Synthesis of Proteins and Circular Peptides Using N‐α‐(1‐Phenyl‐2‐mercaptoethyl) Auxiliaries
Authors: Botti Paolo , Tchertchian Sylvie 
Published: August 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Combinatorial Solid‐Phase Peptide Synthesis and Bioassays
Authors: Shin Dong‐Sik , Kim Do‐Hyun , Chung Woo‐Jae , Lee Yoon‐Sik 
Published: August 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
The Effect of Nitrogen‐Containing Modifiers on the Deprotection of a Carbobenzyloxy‐Protected Amino Acid
Authors: Humphries Kimberly B. , Dunn Tracy D. , Mobus Konrad , Chen Baoshu 
Published: August 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Systematic Design of Amide‐ and Urea‐Type Gelators with Tailored Properties
Authors: Fages Frederic , Voegtle Fritz , Zinic Mladen 
Published: August 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
3‐Aminopyrrolidine Lithium Amides as Chiral Ligands for Alkyllithium Derivatives: Synthesis, NMR Analysis, and Computational Study of Their Mixed Aggregates
Authors: Harrison‐Marchand Anne , Valnot Jean‐Yves , Corruble Aline , Duguet Nicolas , Oulyadi Hassan , Desjardins Stephanie , Fressigne Catherine , Maddaluno Jacques 
Published: August 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Metal‐Catalyzed Asymmetric Oxidations Mediated by Optically Pure Furyl Hydroperoxides
Authors: Lattanzi Alessandra , Scettri Arrigo 
Published: August 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Metal/Linked‐BINOL Complexes: Applications in Direct Catalytic Asymmetric Mannich‐Type Reactions
Authors: Shibasaki Masakatsu , Matsunaga Shigeki 
Published: August 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
New Synthetic Reactions Using Conjugate Addition Reactions of Active Methine Compounds to Alkynyl Imines and Ketones
Authors: Hachiya Iwao , Shimizu Makoto 
Published: August 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
The 7 TM G‐Protein‐Coupled Receptor Target Family
Authors: Jacoby Edgar , Bouhelal Rochdi , Gerspacher Marc , Seuwen Klaus 
Published: August 2006

AbstractChemical biology approaches have a long history in the exploration of the G‐protein‐coupled receptor (GPCR) family, which represents the largest and most important group of targets for therapeutics. The analysis of the human genome revealed a significant number of new members with unknown physiological function which are today the focus of many reverse pharmacology drug‐discovery programs. As the seven hydrophobic transmembrane segments are a defining common structural feature of these receptors, and as signaling through heterotrimeric G proteins is not demonstrated in all cases, these proteins are also referred to as seven transmembrane (7 TM) or serpentine receptors. This review summarizes important historic milestones of GPCR research, from the beginning, when pharmacology was mainly descriptive, to the age of modern molecular biology, with the cloning of the first receptor and now the availability of the entire human GPCR repertoire at the sequence and protein level. It shows how GPCR‐directed drug discovery was initially based on the careful testing of a few specifically made chemical compounds and is today pursued with modern drug‐discovery approaches, including combinatorial library design, structural biology, molecular informatics, and advanced screening technologies for the identification of new compounds that activate or inhibit GPCRs specifically. Such compounds, in conjunction with other new technologies, allow us to study the role of receptors in physiology and medicine, and will hopefully result in novel therapies. We also outline how basic research on the signaling and regulatory mechanisms of GPCRs is advancing, leading to the discovery of new GPCR‐interacting proteins and thus opening new perspectives for drug development. Practical examples from GPCR expression studies, HTS (high‐throughput screening), and the design of monoamine‐related GPCR‐focused combinatorial libraries illustrate ongoing GPCR chemical biology research. Finally, we outline future progress that may relate today’s discoveries to the development of new medicines.
Balancing the bipotential gonad between alternative organ fates: A new perspective on an old problem
Authors: Kim Yuna , Capel Blanche 
Published: August 2006

AbstractThe embryonic gonads give rise to one of two morphologically and functionally different organs, a testis or an ovary. Sex determination is the embryonic process that determines the developmental fate of the gonad. In mammals, sex determination is regulated by a DNA binding protein encoded on the Y chromosome, Sry, and it's downstream mediator, Sox9, which trigger testis determination in the bipotential gonad. However, evidence suggests that the extracellular signals. Fgf9 and Wnt4, are also required to establish divergent organogenesis of the gonad. In this review, we discuss how these extracellular signals interface with cell‐autonomous factors to determine the fate of the mammalian gonad, and we derive a model that could provide a molecular explanation for testis determination in vertebrates where Sry is absent. Developmental Dynamics 235:2292–2300, 2006. © 2006 Wiley‐Liss, Inc.
Cloning of vertebrate Protogenin (Prtg) and comparative expression analysis during axis elongation
Authors: Vesque Christine , Anselme Isabelle , Couvé Elisabeth , Charnay Patrick , Schneider‐Maunoury Sylvie 
Published: August 2006

AbstractA murine cDNA encoding Protogenin, which belongs to the DCC/Neogenin family, was cloned in a screen performed to identify novel cDNAs regionally expressed in the neural plate. Isolation of the putative zebrafish orthologues allowed a comparative analysis of the expression patterns of Protogenin genes during embryogenesis in different vertebrate species. From mid‐gastrulation to early somite stages, Protogenin expression is restricted to posterior neural plate and mesoderm, with an anterior limit at the level of the rhombencephalon in mouse, chicken, and zebrafish. During somitogenesis, the expression profiles in the three species share features in the neural tube but present also species‐specific characteristics. The initiation of Protogenin expression just before somitogenesis and its maintenance in the neural tube and paraxial mesoderm during this process suggest a conserved role in axis elongation. Developmental Dynamics 235:2836–2844, 2006. © 2006 Wiley‐Liss, Inc.
Emerging developmental model systems
Authors: Kiefer Julie C. 
Published: August 2006

AbstractThis primer briefly describes four emerging animal model systems that promise to provide insights into specific aspects of developmental biology. Highlighted here are two relatively well‐characterized model systems, Gasterosteus aculeatus (three‐spine stickleback fish) and Schmidtea mediterranea (planarian), as well as two organisms on which research is in its infancy, Carollia perspicillata (short‐tailed fruit bat), and the basal metazoan, Trichoplax adhaerens. Scientists who helped develop these species into model systems discuss why they chose to research these animals. Developmental Dynamics 235:2895–2899, 2006. © 2006 Wiley‐Liss, Inc.
Notch synergizes with axin to regulate the activity of armadillo in Drosophila
Authors: Hayward Penelope , Balayo Tina , Martinez Arias Alfonso 
Published: August 2006

AbstractCell fate decisions require the integration of various signalling inputs at the level of transcription and signal transduction. Wnt and Notch signalling are two important signalling systems that operate in concert in a variety of systems in vertebrates and invertebrates. There is evidence that the Notch receptor can modulate Wnt signalling and that its target is the activity and levels of Armadillo/β‐catenin. Here, we characterize this function of Notch in relation to Axin, a key element in the regulation of Wnt signalling that acts as a scaffold for the Shaggy/GSK3β‐dependent phosphorylation of Armadillo/β‐catenin. While Notch can regulate ectopic Wingless signalling caused by loss of function of Shaggy, it can only partially regulate the ectopic Wnt signalling induced by the loss of Axin function. The same interactions are observed in tissue culture cells where we observe a synergy in between Axin and Notch in the regulation of Armadillo/β‐catenin. Our results provide evidence for a function of Axin in the regulation of Armadillo that is different from its role as a scaffold for GSK3β. Developmental Dynamics 235:2656–2666, 2006. © 2006 Wiley‐Liss, Inc.
Three Dact gene family members are expressed during embryonic development and in the adult brains of mice
Authors: Fisher Daniel A. , Kivimäe Saul , Hoshino Jun , Suriben Rowena , Martin Pierre‐Marie , Baxter Nichol , Cheyette Benjamin N.R. 
Published: August 2006

AbstractMembers of the Dact protein family initially were identified through binding to Dishevelled (Dvl), a cytoplasmic protein central to Wnt signaling. During mouse development, Dact1 is detected in the presomitic mesoderm and somites during segmentation, in the limb bud mesenchyme and other mesoderm‐derived tissues, and in the central nervous system (CNS). Dact2 expression is most prominent during organogenesis of the thymus, kidneys, and salivary glands, with much lower levels in the somites and in the developing CNS. Dact3, not previously described in any organism, is expressed in the ventral region of maturing somites, limb bud and branchial arch mesenchyme, and in the embryonic CNS; of the three paralogs, it is the most highly expressed in the adult cerebral cortex. These data are consistent with studies in other vertebrates showing that Dact paralogs have distinct signaling and developmental roles and suggest they may differentially contribute to postnatal brain physiology. Developmental Dynamics 235:2620–2630, 2006. © 2006 Wiley‐Liss, Inc.