bluuebunny/crossref_metadata_2025_split huggingface dataset:
Les cliniques juridiques : vecteurs d’innovation de l’enseignement du droit de la transition écologique
Authors: Perelman Jeremy , Bouayad Aurélien , Morin Guerry Anaïs 
Published: April 2024

Inspirées en partie par les facultés de droit américaines, les cliniques juridiques se sont développées en France à partir de la fin des années 2000. Leur démultiplication au cours de la précédente décennie révèle la réussite de ce dispositif pédagogique plaçant la pratique et l’action au centre de l’apprentissage du droit. Par l’intermédiaire des projets conduits par les étudiant·es en coopération avec divers types d’acteurs, les cliniques juridiques deviennent des lieux d’expérimentation et de transformation des méthodes d’enseignement du droit. Elles accompagnent l’émergence de concepts et de catégories juridiques nouvelles visant à la concrétisation des intérêts collectifs poursuivis par ces projets. Créé en 2019, le programme « Justice environnementale et transition écologique » (JETE) de la Clinique de l’École de Droit de Sciences Po Paris illustre la richesse des liens tissés entre théorie et pratique dans le cadre de l’enseignement et de la mise en œuvre du droit de la transition écologique.
Enseignement du droit, transition écologique et liberté pédagogique
Authors: Lassalle Maxime 
Published: April 2024

L’enseignement du droit va-t-il naturellement évaluer pour appréhender les questions liées à la transition écologique ? N’existe-t-il pas des contraintes structurelles qui orientent l’exercice de la liberté pédagogique des enseignants-chercheurs ? On peut estimer que les programmes de certains concours ou examens auxquels mènent les études en droit ou encore l’approche par compétences pourraient être vus à la fois comme des freins et des leviers conditionnant la place donnée aux enjeux de la transition écologique. Le rôle de ces contraintes structurelles reste toutefois encore très indéterminé.
Des grands travaux à l’âge du Bronze... L’enceinte de la Tourelle à Lamballe
Authors: Blanchet Stéphane 
Published: April 2024

De grandes enceintes doublées d’un rempart comme celle de la Tourelle à Lamballe ou de Bellevue à Lannion (toutes deux en Côte-d'Armor) ont été récemment découvertes dans le cadre de l’archéologie préventive. D’autres ouvrages fossoyés comme ceux du Val Aubin à Lamballe, de Beg ar Menez Traon à Quimper (Finistère) ou de La Rochette à Mauron (Morbihan) ont été repérés lors de prospections aériennes. Toutes ces structures remarquables tranchent nettement, par leurs dimensions et l’importance des moyens mis en œuvre pour les réaliser, avec les habitats légers et dispersés qui sont généralement mis au jour. À l’instar des imposants tumuli édifiés dans la péninsule armoricaine, ces « grands travaux » posent de nombreuses questions en termes de hiérarchisation de l’occupation et, plus largement, en termes d’organisation sociale.
Ingénierie et grands travaux. Les fondations du cirque d’Arles
Authors: Sintès Claude 
Published: April 2024

Le cirque romain d’Arles, dont la construction a démarré dans les années 148-149, a mobilisé des moyens considérables pour son édification : c’est, avec l’amphithéâtre et le forum, l’un des plus importants « grand travaux » entrepris dans cette ville. Le bâtiment, installé dans une terre à portance faible le long du Rhône, a nécessité la mise en œuvre de fondations puissantes, reposant sur un pilotis de bois de grande ampleur. Cet article expose les techniques utilisées par les ingénieurs romains et l’organisation très coordonnée que cela a supposé entre les divers corps de métier impliqués : bucherons, transporteurs, sapeurs puis maçons.
Les puits du second âge du Fer à Toulouse. Dix ans de recherches préventives : problématiques, méthodes, résultats et perspectives
Authors: Requi Christophe 
Published: April 2024

Les fouilles préventives menées dans le quartier Saint-Roch/Saint-Agne de Toulouse ont permis de reconsidérer le dossier des puits toulousains du second âge du fer. Les dépôts identifiés en leur sein avaient longtemps caractérisé la fonction de ces puits : funéraire ou cultuelle. Grâce à une méthodologie adaptée et à la pérennité des équipes de recherches, nous avons reconstitué le cycle d’utilisation de ces structures : de leur conception à leur découverte par l’archéologue. Ces résultats associés aux études géomorphologiques du secteur permettent d’envisager sérieusement une fonction en relation avec la gestion de l’eau. Des dépôts sont parfois identifiés au sein de ces puits à eau, en général juste avant la phase d’abandon, mais ils ne caractérisent plus la fonction primaire du puits. Cette évolution de l'interprétation conduit donc à considérer ces derniers comme des indices d’habitat au sens large et à les intégrer désormais à la sphère de la vie quotidienne.
La lutte contre les discriminations : chronique de l’activité du Défenseur des droits en 2023
Authors: Durand Jeanne , Mokhnachi Cassandre 
Published: April 2024

Au cours de l’année 2023, le Défenseur des droits (DDD) a une fois encore été saisi à de multiples reprises en matière de discrimination. Pour l’examen des situations, l’autorité indépendante réalise une analyse approfondie, ce qui lui permet de caractériser des discriminations, même lorsqu’elles ne sont pas visibles de prime abord. Par ailleurs, les observations que le DDD peut présenter au juge - que celui-ci l’ait ou non sollicité - sont un éclairage utile. Néanmoins, l’analyse comparative entre les décisions du Défenseur et les décisions rendues par les juridictions conduisent à relativiser l’influence de l’Institution.
Altering β Cell Antigen Exposure to Exhausted CD8+ T Cells Prevents Autoimmune Diabetes in Mice
Authors: De George David J , Jhala Gaurang , Selck Claudia , Trivedi Prerak , Brodnicki Thomas C , Mackin Leanne , Kay Thomas W , Thomas Helen E , Krishnamurthy Balasubramanian 
Published: April 2024

Abstract
Chronic destruction of insulin-producing pancreatic β cells by T cells results in autoimmune diabetes. Similar to other chronic T cell–mediated pathologies, a role for T cell exhaustion has been identified in diabetes in humans and NOD mice. The development and differentiation of exhausted T cells depends on exposure to Ag. In this study, we manipulated β cell Ag presentation to target exhausted autoreactive T cells by inhibiting IFN-γ–mediated MHC class I upregulation or by ectopically expressing the β cell Ag IGRP under the MHC class II promotor in the NOD8.3 model. Islet PD-1+TIM3+CD8+ (terminally exhausted [TEX]) cells were primary producers of islet granzyme B and CD107a, suggestive of cells that have entered the exhaustion program yet maintained cytotoxic capacity. Loss of IFN-γ–mediated β cell MHC class I upregulation correlated with a significant reduction in islet TEX cells and diabetes protection in NOD8.3 mice. In NOD.TII/8.3 mice with IGRP expression induced in APCs, IGRP-reactive T cells remained exposed to high levels of IGRP in the islets and periphery. Consequently, functionally exhausted TEX cells, with reduced granzyme B expression, were significantly increased in these mice and this correlated with diabetes protection. These results indicate that intermediate Ag exposure in wild-type NOD8.3 islets allows T cells to enter the exhaustion program without becoming functionally exhausted. Moreover, Ag exposure can be manipulated to target this key cytotoxic population either by limiting the generation of cytotoxic TIM3+ cells or by driving their functional exhaustion, with both resulting in diabetes protection.
Evaluation of bond strength in customizing fiber post using translucent resins photoactivated by different light-emitting diodes
Authors: Barros Antonia Patricia O. , Costa Joatan Lucas de Sousa Gomes , de Melo Alencar Cristiane , Galvani Lucas David , Dantas Andrea Abi Rached , Kuga Milton Carlos 
Published: April 2024

Abstract

Aims:
The objective of the study was to evaluate two translucent resin composite systems for customizing light-polymerized fiber posts with light-emitting diode (LED) curing units regarding adhesion using conventional cement at 24 h and 6 months.

Settings and Design:
This was an experimental in vitro study.

Methods:
Forty roots were prepared and divided into four groups (n = 10): ZV-Z350 resin and LED Valo; ZR-Z350 resin and LED Radii-Cal; OV-Opallis resin and LED Valo; and OR-Opallis resin and LED Radii-Cal. The fiber post was customized and cemented with conventional resin cement and was photoactivated by two different sources.

Statistical Analysis Used:
The data were subjected to two-way ANOVA and Tukey’s post hoc tests (P = 0.05). The data regarding the pattern of adhesive failures were described in terms of the frequency of occurrence in each third of the postspace.

Results:
Both at 24 h and 6 months, bond strength among groups was similar, regardless of the analyzed postspace 3rd (P > 0.05). Adhesive failure Type 4 was the most frequent in all thirds.

Conclusions:
Customizing the fiber post with Z350 and Opallis has the same effect on bond strength and adhesive failure pattern, regardless of the LED curing units used for photopolymerization.
Morphometric analysis of the relationship between maxillary posterior teeth and maxillary sinus floor in central Indian population: A cone-beam computed tomography study
Authors: Akotiya Bhavya Rajendra , Surana Anjali , Chauhan Priya , Saha Suparna G. , Agarwal Rolly S. , Vashisht Anu 
Published: April 2024

Abstract

Background:
The relationship between the maxillary sinus (MS) and the root apices of posterior teeth is of significant clinical relevance as it influences the diagnosis and treatment planning when operating in the posterior areas of the maxilla. The aim of this study, therefore, is to assess this anatomic relationship and evaluate the propensity of roots of posterior maxillary teeth to be intruded into the MS space using cone-beam computed tomography (CBCT) scanning.

Materials and Methods:
One thousand CBCT scans of patients, aged 20 years or above, were analyzed in the study. The distance from the MS floor to the root apices of the posterior teeth was measured and the relationship between the MS and the posterior teeth roots were recorded, based on Kwak’s and Didilescu’s classification.

Results:
Based on Kwak’s classification, type I configuration was frequently observed in the maxillary posterior teeth, followed by type II. Based on Didilescu’s classification, the longest distance, among premolars, was observed between the palatal root of the left 1st premolar and MS, i.e., 8.2467 mm. Among molars, the longest distance was observed between mesiobuccal root of the right first molar and MS, i.e., 5.8966 mm. The shortest distance, among premolars, was observed between the buccal root of the left second premolar and MS, i.e., 3.5500 mm, and among molars, the shortest distance was between the mesiobuccal root of the left second molar and MS, i.e., 1.3556 mm.

Conclusion:
From the present study, it may be concluded that, among the central Indian population, mesiobuccal root of the second molars and buccal root of the second premolars show the closest proximity to the MS floor. Therefore, any surgical or endodontic intervention in the vicinity of these roots must be performed with utmost care.
Efficiency of a high-speed handpiece with anti-retraction adapter to minimize cross-contamination during the routine dental procedure: A clinical study
Authors: Subhiksha S. R. , Arul Buvaneshwari , Natanasabapathy Velmurugan 
Published: April 2024

Abstract

Background:
This study aimed to detect the efficiency of anti-retraction adapter (ARA) attached to a handpiece (HP).

Materials and Methods:
Two types of dental HP with and without the ARA were used in this study. A total of 30 sets of samples were obtained from two groups and were subjected to a real-time reverse transcriptase-polymerase chain reaction (RT-PCR) and microbial culture for quantitative analysis of total bacterial and Legionella count.

Statistical Analysis Used:
The data obtained were tabulated using the Statistical Package for the Social Sciences (SPSS, IBM version 26.0) for statistical analysis.

Results:
The water samples were analyzed using PCR, Legionella-specific PCR, and culture-based analysis. In Groups 1 and 2, there was no significant difference between bacterial load in the water samples taken from both HP and coupling of the Dental Unit Waterline (DUWL).

Conclusions:
The reduction in bacterial load in DUWLs analyzed using quantitative RT-PCR was similar in both experimental groups. Overall, the bacterial load was lower in the group with ARA when compared to the group without ARA but not statistically significant. ARA was not effective in reducing the Legionella species load in DUWLs.
Improving Performance of the Typical User in the Indoor Cooperative NOMA Millimeter Wave Networks with Presence of Walls
Authors: Lam Sinh Cong , Tran Xuan Nam 
Published: April 2024

INTRODUCTION: The beyond 5G millimeter wave cellular network system is expecting to provide the high quality of service in indoor areas. OBJECTIVES: Due to the high density of obstacles, the cooperative communication technique is employed to improve the user's desired signal power by finding more than one appropriate station to serve that user. METHODS: While the conventional system utilizes additional equipment such as Reconfigurable Intelligent Surfaces (RIS) and relays to enable the cooperative features, the paper introduces a new network paradigm that utilizes the second nearest Base Station (BS) of the typical user as the Decode and Forward (DF) relay. Thus, depends on the success of decoding the message from the user' serving BS of the second nearest BS, the typical user can work with and without assistance from the relay whose operation follows the discipline of the power-domain NOMA technique. In the case of with relay assistance, the Maximum Ratio Combining technique is utilized by the typical user to combine the desired signals. RESULTS: To examine the performance of the proposed system, the Nakagami-m and the newly developed path loss model, which considers the density of walls and their properties, are adopted to derive the coverage probability of the user with and without relay assistance. The closed-form expressions of this performance metric are derived by Gauss quadrature and Welch-Satterthwaite approximation.
3D Convolutional Neural Networks for Predicting Protein Structure for Improved Drug Recommendation
Authors: Kiran Sree Pokkuluri , Devi N SSSN Usha 
Published: April 2024

INTRODUCTION: Protein structure prediction is critical for recommendation personalized medicine and drug discovery. This paper introduces a robust approach using 3D Convolution Neural Networks (3D CNN’s) to improve the accuracy of the structure of protein structure thus contributing for the drug recommendation system.
OBJECTIVES: In contrast to conventional techniques, 3D CNNs are able to identify complicated folding patterns and comprehend the subtle interactions between amino acids because they are able to capture spatial dependencies inside protein structures.
METHODS: Data sets are collected from Protein Data Bank, including experimental protein structures and the drugs that interact with them, are used to train the model. With the efficient processing of three-dimensional data, the 3D CNNs exhibit enhanced capability in identifying minute structural details that are crucial for drug binding. This drug recommendation system novel method makes it easier to find potential drugs that interact well with particular protein structures.
RESULTS: The performance of the proposed classifier is compared with the existing baseline methods with various parameters accuracy, precision, recall, F1 score, mean squared error (MSE) and area under the receiver operating characteristic curve (AUC-ROC).
CONCLUSION: Deep learning and 3D structural insights work together to create a new generation of tailored and focused therapeutic interventions by speeding up the drug development process and improving the accuracy of pharmacological recommendations.
Topological generation of simple algebraic groups
Authors: Burness Timothy C. , Gerhardt Spencer , Guralnick Robert M. 
Published: April 2024

Let

G

be a simple algebraic group over an algebraically closed field and let

X

be an irreducible subvariety of

G^{r}

with

r \geqslant 2

. In this paper, we consider the general problem of determining if there exists a tuple

(x_{1}, \ldots, x_{r}) \in X

such that

\langle x_{1}, \ldots, x_{r} \rangle

is Zariski dense in

G

. We are primarily interested in the case where

X = C_{1} \times \cdots \times C_{r}

and each

C_{i}

is a conjugacy class of

G

comprising elements of prime order modulo the center of

G

. In this setting, our main theorem gives a complete solution to the problem when

G

is a symplectic or orthogonal group. By combining our results with earlier work on linear and exceptional groups, this gives an almost complete solution for all simple algebraic groups. We also present several applications. For example, we use our main theorem to show that many faithful representations of symplectic and orthogonal groups are generically free. We also establish new asymptotic results on the probabilistic generation of finite simple groups by pairs of prime order elements, completing a line of research initiated by Liebeck and Shalev over 25 years ago.
The GCMS, antioxidant, and anti-inflammatory activity of the Ayurveda oil, Arukaladi tailam
Authors: Sudhan Aparna , K Prabhu , Balakrishnan Deepalakkshmi , Jones Sumathi , Ramakrishna Rao Mudiganthi , M Kavimani 
Published: April 2024

Ayurvedic tailams have a long history of use and efficacy. They have been used for centuries, with many individuals reporting positive results in managing and improving their health. Ayurvedic tailams typically have fewer side effects compared to synthetic medications, making them a preferred choice for individuals seeking natural remedies and can be applied both externally (for massage) and, in some cases, internally (for specific therapies). This versatility allows for a wide range of applications and health benefits.The current study focuses on the GC MS analysis of Arukaladi tailam, an oil composition used in Ayurveda to treat jaundice when administered topically. Before being subjected to the GC MS analysis, the product was appropriately prepared after being purchased from a reputable Ayurvedic dealer in Chennai, India. The IC50 value of the DPPH assay was found to be 744.7391μl/ml and FRAP reveals that the tailam had good reducing power. Further the anti-inflammatory of the tailam exhibited 14.2% of haemolysis at 1000μl/ml and inhibited protein denaturation by 63.74% with an IC50 value of 789.4013 µl/ml. The presence of biomolecules as shown in the GC MS profile are 2-Fluoro-6-trifluoromethylbenzoic acid, 2- tetradecyl ester, Tridecanol, 2-ethyl-2-methyl-, etc. These chemicals could help the medication work better to treat jaundice.
Whistleblowing, Morality, Good Corporate Governance, The Role of Accountant as A Moderation Variable to Fraud Intention
Authors: Joko Arifianto  , Yvonne Augustine Sudibijo  
Published: April 2024

Purposes - This study aims to investigate the problem solved and resolved by accountants in the country of Indonesia with various educational backgrounds, the scope of business, and experience in their job to examine fraud intention, with the whistleblowing system as a trigger and other variables like good corporate governance, Morality, the role of the accountant as additional variable moderate provides insights on the moderating effect to fraud intention.
Design/methodology/Approach - Data was gathered using a questionnaire survey involving 291 respondents with accountant backgrounds. This study used quantitative research with smart pls 3.3 .3 and also the grand theory of agency theory and fraud triangle theory as a guide to conclude this study.
Findings - The results show that there is a positive relationship between morality, Whistleblowing system, and Good Corporate Governance, to fraud intention. The moderate variables provide partial support that the role of accountants has a positive significant impact with good corporate governance to the fraud intention.
Research limitation/implications - The role of accountants in moderating whistleblowing against fraud in the future should be added with other dimensions such as professional skepticism, competence, and perceived behavior.
Practical implications – this study contributes to the development of ideas to reduce fraud intention through critical studies of any variables including whistleblowing, Good Corporate Governance, Morality, also the role of accountants.
Social Implications – this study argues that consistently by the major of morality personal is a must behave in a social environment, especially in the organization of a company or other society.
Originality/Value – this study uses the role of the accountant as a proxy to contribute to the analytical fraud diamond theory. There is limited implication between whistleblowing the fraud intention because whistleblowing depends on practically system good corporate governance.
An Electrical Power Inventory and Monitoring System
Authors: Bravo Corleto 
Published: April 2024

The Inventory Management and Monitoring System is a software that is helpful for the various business sectors that operate in stores, products, and services where storeowners, products and services proprietors keep the records of sales and purchases, supply and demand, and risk and opportunities. A mismanaged inventory means disappointed customers, too much cash tied up in warehouses, slower sales, and sometimes detrimental to the work relation environment, investments and businesses, and most probably financial losses. Inventory control problems often result in record and physical count discrepancies which may ultimately lead to higher than preferred inventory levels. Conversely, accurate inventory records result in lower inventory investment and are the foundation for forecasting, ordering, tracking, vendor evaluation, dead stock, and administration plans and decisions.

The researcher observed that most of the application of the inventory system was sales and products. Through this study, the researcher applied inventory in terms of electrical maintenance relations which includes electrical supplies, devices and equipment, services, and electrical power consumption. An Agile software development methodology was used in developing the system. The inventory archive maintenance system was developed using Java, HTML, CSS, PHP, PhpMyAdmin, and MySQL. The Inventory System includes Messaging, Supplies Inventory, Job Orders, Repair Records, and Wattage Consumption. Integration of disciplines made the study finished and the user’s manual was produced for guides and references for the use of the system.