bluuebunny/crossref_metadata_2025_split huggingface dataset:
Salvage Algorithm for Deep Surgical Site Infections after HTO with Unstable Bone Situation Using a Hexapod System – Primary Results
Authors: Baumgartner Heiko , Finger Felix , Ahrend Marc-Daniel , Histing Tina , Grünwald Leonard 
Published: March 2024

AbstractThe incidence of deep surgical site infections following high tibial osteotomy (HTO)
ranges between 0.4 to 4.7%. It is a severe complication with a high risk for poor clinical
outcome. The aim of this study was to proof that a salvage algorithm for infected HTO with
unstable bone situation leads to an infection-free status and bone union of the osteotomy
and that correct limb alignment can be restored with good knee function.The study included seven patients with peri-implant infections following HTO. Infections
occurred 83 ± 58.9 days (range: 24–191) after HTO. All patients underwent the “RESTORE”
algorithm: patients received (1) REmoval of the HTO hardware and extensive debridement; (2)
the osteotomy was STabilized with a hexapod external fixator (Taylor Spatial Frame, TSF);
(3) the osteotomy gap was Opened; and (4) the alignment was REconstructed using the TSF,
aiming for the intended limb alignment of the initial HTO. Patient-reported outcomes were
assessed 22–36 months after removal of the TSF.After 24 weeks (range: 11–35), an infection-free status and bone healing were achieved.
In all cases, the limb was saved, and the previously targeted mechanical axis of the lower
limb was restored. All patients reached full extension of the knee joint and at least 110°
of flexion. For KOOS: Symptoms 67.86 ± 18.1, Pain 73.41 ± 16.58, ADL 78.99 ± 21.32, Sports
52.14 ± 25.96, and QoL 41.96 ± 24.66. OKS 35.71 ± 8.8, SF-12 Physical Health 38.89 ± 10.3,
and SF-12 Mental Health 46.86 ± 13.76.The “RESTORE” algorithm is a safe and effective salvage procedure. The concept allows
for saving the limb and obtaining the previously planned limb alignment. Patient-reported
outcome measures showed slightly lowered values than healthy samples, but substantially
better values than patients awaiting HTO. Due to the possibility of initial full
weight-bearing, the risk of higher morbidity caused by immobilization is minimized.
A comprehensive examination of small-bowel capsule endoscopy in Spanish centers to meet European Society of Gastrointestinal Endoscopy standards
Authors: Gómez Villagrá Míriam , de Frías César Prieto , Martinez-Acitores de la Mata Diego , Alonso-Sierra Maite , Alonso-Lazaro Noelia , Caballero Noemí , Sanchez Ceballos Francisco , Compañy Luis , Egea Valenzuela Juan , Esteban Pilar , Farráis Sergio , Fernández-Urién Ignacio , Galvez Consuelo , García Almudena , García Lledó Javier , González Suárez Begoña , Jiménez-García Victoria-Alejandra , Lujan-Sanchís Marisol , Mateos Muñoz Beatriz , Romero-Mascarell Cristina , San Juan Acosta Mileidis , Valdivielso Cortázar Eduardo , Giordano Antonio , Carretero Cristina 
Published: March 2024

Abstract
Background and study aims In 2019, the European Society of Gastrointestinal Endoscopy (ESGE) created a working group to develop technical and quality standards for small-bowel capsule endoscopy (SBCE) to improve the daily practice of endoscopy services. They developed 10 quality parameters, which have yet to be tested in a real-life setting. Our study aimed to evaluate the accomplishment of the quality standards in SBCE established by the ESGE in several Spanish centers.

Materials and methods An online survey of 11 multiple-choice questions related to the ESGE performance measures was sent to Spanish centers with experience in SBCE. In order to participate and obtain reliable data, at least 100 questionnaires had to be answered per center because that is the minimum number established by ESGE.

Results 20 centers participated in the study, compiling 2049 SBCEs for the analysis. Only one of 10 performance measures (cecal visualization) reached the minimum standard established by the ESGE. In five of 10 performance measures (Indication, lesion detection rate, terminology, and retention rate) the minimum standard was nearly achieved.

Conclusions Our study is the first multicenter study regarding SBCE quality performance measures in a real setting. Our results show that the minimum standard is hardly reached in most procedures, which calls into question their clinical applicability in real life. We suggest performing similar studies in other countries to evaluate whether there is a need for quality improvement programs or a need to reevaluate the minimum and target values published so far.
High spin-Chern-number insulator in α-antimonene with a hidden topological phase
Authors: Wang Baokai , Zhou Xiaoting , Hung Yi-Chun , Lin Yen-Chuan , Lin Hsin , Bansil Arun 
Published: March 2024

Abstract
For a time-reversal symmetric system, the quantum spin Hall phase is assumed to be the same as the

Z

2

topological insulator phase in the existing literature. The spin Chern number

C

s

is presumed to yield the same topological classification as the

Z

2

invariant. Here, by investigating the electronic structures of monolayer α-phase group V elements, we uncover the presence of a topological phase in α-Sb, which can be characterized by a spin Chern number

C

s

= 2, even though it is

Z

2

trivial. Although α-As and Sb would thus be classified as trivial insulators within the classification schemes, we demonstrate the existence of a phase transition between α-As and Sb, which is induced by band inversions at two generic k points. Without spin–orbit coupling (SOC), α-As is a trivial insulator, while α-Sb is a Dirac semimetal with four Dirac points (DPs) located away from the high-symmetry lines. Inclusion of the SOC gaps out the DPs and induces a nontrivial Berry curvature, endowing α-Sb with a high spin Chern number of

C

s

= 2. We further show that monolayer α-Sb exhibits either a gapless band structure or a gapless spin spectrum on its edges, as expected from topological considerations.
Symmetry breaking in vanadium trihalides
Authors: Camerano Luigi , Profeta Gianni 
Published: March 2024

Abstract
In the light of new experimental evidence we study the insulating ground state of the

3

d
2

-transition metal trihalides VX
3 (X = Cl, I). Based on density functional theory with the Hubbard correction we systematically show how these systems host multiple metastable states characterised by different orbital ordering and electronic behaviour. Our calculations reveal the importance of imposing a precondition in the on site d density matrix and of considering a symmetry broken unit cell to correctly take into account the correlation effects in a mean field framework. Furthermore we ultimately found a ground state with the

a

1
g

orbital occupied in a distorted VX
6 octahedra driven by an optical phonon mode.
Influence of acceleration stage electrode voltage on the performance of double-stage Hall effect thruster with adjustable zero magnetic point
Authors: CHEN 陈 Long 龙 , GAO 高 Weifu 维富 , CUI 崔 Zuojun 作君 , DUAN 段 Ping 萍 , XU 许 Xuesong 雪松 , KAN 阚 Zichen 子晨 , TAN 檀 Congqi 聪琦 , CHEN 陈 Junyu 俊宇 
Published: March 2024

Abstract
The configuration of electrode voltage and zero magnetic point position has a significant impact on the performance of the double-stage Hall effect thruster. A 2D-3V model is established based on the two-magnetic peak type double-stage Hall thruster configuration, and a particle-in-cell simulation is carried out to investigate the influences of both acceleration electrode voltage value and zero magnetic point position on the thruster discharge characteristics and performances. The results indicate that increasing the acceleration voltage leads to a larger potential drop in the acceleration stage, allowing ions to gain higher energy, while electrons are easily absorbed by the intermediate electrode, resulting in a decrease in the anode current and ionization rate. When the acceleration voltage reaches 500 V, the thrust and efficiency are maximized, resulting in a 15% increase in efficiency. After the acceleration voltage exceeds 500 V, a potential barrier forms within the channel, leading to a decrease in thruster efficiency. Further study shows that as the second zero magnetic point moves towards the outlet of the channel, more electrons easily traverse the zero magnetic field region, participating in the ionization. The increase in the ionization rate leads to a gradual enhancement in both thrust and efficiency.
Associations Between Psychological Factors and Adherence to Health Behaviors After Percutaneous Coronary Intervention: The Role of Cardiac Rehabilitation
Authors: Douma Emma R , Kop Willem J , Kupper Nina 
Published: March 2024

Abstract

Background
Cardiac rehabilitation (CR) participation after percutaneous coronary intervention (PCI) for coronary heart disease lowers the disease burden and risk of recurrent cardiac events. Examining psychological factors may improve post-PCI health behavior adherence.

Purpose
To determine whether psychological factors are associated with post-PCI health behavior adherence, and the role of CR participation.

Methods
Data from 1,682 patients (22.1% female, Mage = 64.0, SDage = 10.5 years) from the THORESCI cohort were included. Adjusted mixed models were used to examine associations between psychological factors and the 1-year course of health behaviors, using interactions to test for moderation by CR participation.

Results
Psychological factors were associated with the trajectories of adherence to medical advice, exercise, and diet. The strongest association found was between optimism and the trajectory of dietary adherence (B: = −0.09, p = .026). Patients with high optimism levels had a worse trajectory of dietary adherence compared to patients with low to middle optimism levels. Participation in CR buffered the associations of high anxiety, pessimism, and low to middle resilience, but strengthened the associations of high stress in the past year with the probability of smoking.

Conclusions
Psychological factors are associated with post-PCI health behavior adherence, but the pattern of associations is complex. Patients with high levels of anxiety, pessimism, and low to middle resilience levels may disproportionately benefit from CR. Cardiac rehabilitation programs could consider this to improve post-PCI health behavior adherence.

Clinical Trials Registration #
NCT02621216.
Research on arthropod vectors of plant pathogens in a post-Subsection Cc world: current status and future prospects
Authors: Mauck Kerry E , Eigenbrode Sanford D 
Published: March 2024

Abstract
The study of herbivorous arthropod vectors of plant pathogens has been a subdiscipline within entomology for more than a century. It was recognized as a unique field with the establishment of a Subsection (Cc) in the Entomological Society of America (ESA) from 1953 through 2007. During that period, work in the field expanded from an initial emphasis on management of vector-borne plant pathogens to include biology of the pathosystems. Since 2007, when ESA reorganized the subsections within the society, work on herbivorous vectors of plant pathogens has continued to grow. This article briefly summarizes the work in this field prior to, during, and after the ESA Subsection Cc era. We identify and describe 4 research areas that have characterized the field since 2007: Molecular mechanisms of vector–plant interactions, managing vectors and pathogen transmission in agriculture, illuminating the ecology of vectors and pathogens outside of crops, and pathogen manipulation of host phenotypes and vector behavior. We then identify 10 frontiers and prospects for the field in the coming years that build on these 4 research areas, ranging from molecular and cellular aspects to ramifications for managed and natural ecosystems. We also examine trends in funding and professional opportunities for scientists working on herbivorous vectors and pathogens. Finally, we renew the call for greater integration of work addressing vector-borne plant, animal, and human pathogens due to fundamental similarities in their biology and importance for human well-being within an expanded understanding of the “One Health” paradigm, which currently emphasizes human and animal health.
Jurisdictional challenges under section 67 and section 30(1)(b): reflections on procedural irregularity in tribunal constitution
Authors: Goh Nelson , Newton James 
Published: March 2024

Abstract
This article explores the Law Commission’s proposed reforms to section 67 of the English Arbitration Act 1996 and, in particular, the missed opportunity to establish a threshold test for challenges to the substantive jurisdiction of an arbitral tribunal. The current reforms are chiefly concerned with the manner through which the English Courts are to conduct a section 67 challenge, rather than the principles to be applied. Through a comparative assessment of the approach in other jurisdictions, we propose that a two-factor test be introduced that requires any challenge of substantive jurisdiction to demonstrate a breach that (i) is more than de minimis and (ii) results in material prejudice. Such a test would help to dissuade frivolous challenges, bolster England as a pro-arbitration destination, and bring England further into line with other, well-respected jurisdictions that impose similar tests.
Sequential combination of sonic hedgehog inhibitors followed by consolidation radiotherapy in locally advanced basal cell carcinoma
Authors: Boileau Marie , Dubois Manon , Pruvot Clément , Desmedt Eve , Templier Carole , Meyer Nicolas , Mirabel Xavier , Mortier Laurent 
Published: March 2024

Abstract

Background
Sonic hedgehog inhibitors (SHHis) are an effective treatment in locally advanced basal cell carcinoma (laBCC). However, the use of these drugs is limited by adverse events, and relapse at discontinuation in around one-half of patients. A few cases of patients treated concomitantly by radiotherapy (RT) and SHHis have been reported in the literature, suggesting that the combination results in an improved overall response. Maintaining complete response after stopping treatment is a concern, especially as resuming treatment in the case of relapse does not guarantee a new therapeutic response. The optimal combination and sequence of treatment to improve local control of laBCCs are not yet defined.

Objectives
We hypothesized that consolidation RT after complete response to SHHis could reduce the risk of relapse at discontinuation.

Methods
We present a case series of patients with laBCCs who achieved complete response after SHHi treatment and were treated with consolidation RT. Patients were evaluated by a skin cancer board. The closure RT technique and dosage were refined by a radiotherapist.

Results
Eleven patients were included. SHHis were prescribed for a median 5 months (range 4–11). Consolidation RT was performed after complete response to SHHis and discontinuation. RT was delivered at a median dose of 45 Gy (range 40.5–66) in 10 fractions (range 9–33). With a median follow-up of 23 months, all patients maintained complete clinical response. This strategy was well tolerated with no grade 3 adverse events.

Conclusions
SHHi treatment followed by consolidation RT after drug discontinuation seems effective and safe. Further studies are needed to develop a precise strategy for the management of laBCCs.
Association of cumulative health status with subsequent mortality in patients with acute heart failure
Authors: Peng Yue , He Guangda , Wang Wei , Lei Lubi , Li Jingkuo , Pu Boxuan , Huo Xiqian , Yu Yanwu , Zhang Lihua , Li Jing 
Published: March 2024

Abstract

Aims
We aim to examine the association between long-term cumulative health status and subsequent mortality among patients with acute heart failure (HF).

Methods and results
Based on a national prospective cohort study of patients hospitalized for HF, we measured health status by Kansas City Cardiomyopathy Questionnaire (KCCQ)-12 at four time points, i.e. admission and 1, 6 and 12 months after discharge. Cumulative health status was interpreted by cumulative KCCQ-12 score and cumulative times of good health status. Outcomes included subsequent all-cause and cardiovascular mortality. Multivariable Cox proportional hazard models were performed to examine the association between cumulative health status and subsequent mortality. Totally, 2328 patients {36.7% women with median age 66 [interquartile range (IQR): 56–75] years} were included, and the median follow-up was 4.34 (IQR: 3.93–4.96) years. Compared with quartile 4, the lowest quartile 1 had the highest hazard ratio (HR) for all-cause mortality [2.96; 95% confidence interval (CI): 2.26–3.87], followed by quartile 2 (1.79; 95% CI: 1.37–2.34) and quartile 3 (1.62; 95% CI: 1.23–2.12). Patients with zero times of good health status had the highest risk of all-cause mortality (HR: 2.41, 95% CI: 1.69–3.46) compared with patients with four times of good health status. Similar associations persisted for cardiovascular mortality.

Conclusion
A greater burden of cumulative health status indicated worse survival among patients hospitalized for HF. Repeated KCCQ measurements could be helpful to monitor long-term health status and identify patients vulnerable to death.
Restoring Obrecht’s Missa Scaramella
Authors: Fitch Fabrice 
Published: March 2024

Abstract
This article reports on the restoration of the four-voice Missa Scaramella by Jacob Obrecht. Preserved uniquely in Berlin, Former Preußische Staatsbibliothek, Ms. Mus. 40634 (now in Kraków, Biblioteka Jagiellońska), only two of the original partbooks remain, leaving the discantus and tenor parts to be supplied in their entirety. The work, begun with the late Philip Weller, has been completed with the assistance of Paul Kolb. I consider the specific challenges it has entailed and its implications for the practice of restoring fragmentary polyphonies, with reference to two sections, which pose very different challenges. In particular, the statements of the Italian monophonic tune that serves as the work’s model have had to be identified. Often this has been straightforward, but in a few cases it has been less so. I also attempt to draw a few general conclusions about the process of restoration. The restorer’s principal focus is attentiveness to the implications of the extant material. Obrecht’s compositional practice might be described as a ‘game of consequences’, which means that the clues in the extant voices are perhaps especially plentiful and suggestive.
Digest: Does the insertion preference of a transposable element represent a strategy for the mitigation of genetic conflicts with the host?
Authors: Zattera Michelle Louise , Bruschi Daniel Pacheco 
Published: March 2024

Abstract
Transposable elements can exhibit a predilection for specific insertion regions. In a recent study, Munasinghe et al. (2023) consider how variation in where TE families prefer to insert within the genome influences their copy number evolution. The study emphasizes how a preference for neutral insertion sites is only advantageous in conjunction with host restriction mechanisms, which suggests that insertion preference may be a strategy to mitigate genetic conflicts with the host.
The contribution of an X chromosome QTL to non-Mendelian inheritance and unequal chromosomal segregation in Auanema freiburgense
Authors: Al-Yazeedi Talal , Adams Sally , Tandonnet Sophie , Turner Anisa , Kim Jun , Lee Junho , Pires-daSilva Andre 
Published: March 2024

Abstract
Auanema freiburgense is a nematode with males, females, and selfing hermaphrodites. When XO males mate with XX females, they typically produce a low proportion of XO offspring because they eliminate nullo-X spermatids. This process ensures that most sperm carry an X chromosome, increasing the likelihood of X chromosome transmission compared to random segregation. This occurs because of an unequal distribution of essential cellular organelles during sperm formation, likely dependent on the X chromosome. Some sperm components are selectively segregated into the X chromosome's daughter cell, while others are discarded with the nullo-X daughter cell. Intriguingly, the interbreeding of 2 A. freiburgense strains results in hybrid males capable of producing viable nullo-X sperm. Consequently, when these hybrid males mate with females, they yield a high percentage of male offspring. To uncover the genetic basis of nullo-spermatid elimination and X chromosome drive, we generated a genome assembly for A. freiburgense and genotyped the intercrossed lines. This analysis identified a quantitative trait locus spanning several X chromosome genes linked to the non-Mendelian inheritance patterns observed in A. freiburgense. This finding provides valuable clues to the underlying factors involved in asymmetric organelle partitioning during male meiotic division and thus non-Mendelian transmission of the X chromosome and sex ratios.
Occlusal force orchestrates alveolar bone homeostasis via Piezo1 in female mice
Authors: Yang Yiling , Dai Qinggang , Gao Xin , Zhu Yanfei , Chung Mi Ri , Jin Anting , Liu Yuanqi , Wang Xijun , Huang Xiangru , Sun Siyuan , Xu Hongyuan , Liu Jingyi , Jiang Lingyong 
Published: March 2024

Abstract
Healthy alveolar bone is the cornerstone of oral function and oral treatment. Alveolar bone is highly dynamic during the entire lifespan and is affected by both systemic and local factors. Importantly, alveolar bone is subjected to unique occlusal force in daily life, and mechanical force is a powerful trigger of bone remodeling, but the effect of occlusal force in maintaining alveolar bone mass remains ambiguous. In this study, the Piezo1 channel is identified as an occlusal force sensor. Activation of Piezo1 rescues alveolar bone loss caused by a loss of occlusal force. Moreover, we identify Piezo1 as the mediator of occlusal force in osteoblasts, maintaining alveolar bone homeostasis by directly promoting osteogenesis and by sequentially regulating catabolic metabolism through Fas ligand (FasL)-induced osteoclastic apoptosis. Interestingly, Piezo1 activation also exhibits remarkable efficacy in the treatment of alveolar bone osteoporosis caused by estrogen deficiency, which is highly prevalent among middle-aged and elderly women. Promisingly, Piezo1 may serve not only as a treatment target for occlusal force loss-induced alveolar bone loss but also as a potential target for metabolic bone loss, especially in older patients.