bluuebunny/crossref_metadata_2025_split huggingface dataset:
Factors Related to Type of Endometrial Cancer in RSUP Dr. M. Djamil Padang
Authors: Helmanda Shylvia , Yusrawati Yusrawati 
Published: March 2024

Objective: This study aims to determine the relationship of risk factors with type of endometrial cancer.Method: This study used a cross sectional design in patients with endometrial cancer. Sampling uses total sampling technique, with a total sample of fifty six people. Data were obtained from the anatomical pathology section and medical records of Dr. RSUP M. Djamil Padang from 2016 until 2018. Analysis of data using Chi-Square test and logistic regressionResult: In this study, type I endometrial cancer is 75% cases while type II is 25% cases. Age, parity, diabetes mellitus, hypertension, genetics history and exclusive breastfeeding have no association with the type of endometrial cancer. The age of menarche and BMI have a relationship with the type of endometrial cancer. The dominant factor associated with the type of endometrial cancer is BMI (p = 0.042; OR = 6.547; 95% CI = 1.067-40.169), age (p = 0.037; OR = 4.854; 95% CI = 1.096-21.493), and age of menarche (p = 0.054; OR = 4.590; 95% CI = 0.974-21.635).Conclusion: On this research, BMI, age and age of menarche are the most dominant factor associated with the type of endometrial cancer. Faktor yang Berhubungan dengan Tipe Kanker Endometrium di RSUP Dr. M. Djamil PadangAbstrakTujuan: Penelitian ini bertujuan untuk mengetahui hubungan faktor risiko dengan tipe kanker endometrium.Metode: Penelitian ini menggunakan desain cross sectional pada penderita kanker endometrium. Pengambilan sampel menggunakan teknik total sampling, dengan jumlah sampel sebanyak 56 orang. Data diperoleh dari bagian patologi anatomi dan rekam medik RSUP Dr. M. Djamil Padang periode 2016 – 2018. Analisis data menggunakan uji Chi-Square dan regresi logistic.Hasil: Pada penelitian ini ditemukan 75% kasus merupakan kanker endometrium tipe 1 dan 25% kanker endometrium tipe II. Usia, paritas, diabetes mellitus, hipertensi, riwayat genetik dan pemberian asi eksklusif tidak memiliki hubungan dengan tipe kanker endometrium. Usia menarche dan IMT memiliki hubungan dengan tipe kanker endometrium. Faktor yang dominan berhubungan dengan tipe kanker endometrium adalah IMT (p = 0,042; OR = 6,547; 95% CI = 1,067-40,169), usia (p = 0,037; OR = 4,854; 95% CI = 1,096-21,493), dan usia menarche (p = 0,054; OR = 4,590; 95% CI = 0,974-21,635).Kesimpulan: Pada penelitian ini, IMT, usia dan usia menarche merupakan faktor yang paling dominan mempengaruhi tipe kanker endometriumKata kunci: Kanker Endometrium, Faktor Risiko.
Recurrent multi-drug-resistant tuberculosis with unilateral destroyed lung in pregnancy: a case report
Authors: Febriana Irene Sinta , Atikah Sayugo , Pudyastuti Sri 
Published: March 2024

Background: Multi-drug-resistant Tuberculosis (MDR-TB) remains a public health problem in developing countries such as Indonesia. The extensive parenchymal damage due to MDR-TB could manifest as an irreversible destroyed lung, leading to respiratory and also cardiovascular complication. Its occurrence in pregnancy is uncommon but is highly associated with higher mortality and morbidity for both maternal and fetal.Case Report: We report a case of 24 year old primigravida in National Respiratory Center Hospital, diagnosed with an unilateral destroyed lung due to MDR-TB in pregnancy at 32 weeks of gestational age. On initial presentation, she reported fatigue, nausea, night sweats, chronic dyspnoe and was found to have complete left destroyed lung. Her disease was managed during pregnancy using long-term oxygen therapy despite persistent desaturation.Conlusion: Aside from frequent monitoring, prolonged oxygen therapy might benefit the chronic hypoxia condition in gestational destroyed lung due to previous MDR-TB infection, for preventing maternal-fetal mortality and morbidities, such as respiratory failure and IUGR.AbstrakLatar Belakang: Tuberkulosis Multi-drug-resistant (TB-MDR) tetap menjadi masalah kesehatan pada negara berkembang, seperti Indonesia. Kerusakan parenkin luas yang diakibatkan oleh infeksi TB-MDR dapat bermanifestasi sebagai kerusakan paru ireversibel, dengan komplikasi respiratorik dan kardiovaskular. Kejadian kerusakan paru akibat TB-MDR dalam kehamilan jarang terjadi, namun berdampak pada peningkatan mortalitas dan morbiditas pada janin dan ibu. Laporan Kasus: Studi ini melaporkan kasus perempuan primigravida 24 tahun didiagnosa dengan kerusakan paru unilateral akibat infeksi TB-MDR pada kehamilan 32 minggu di RS Pusat Paru Nasional. Pada pemeriksaan awal, didapatkan pasien mengeluhkan kelelahan kronik, nausea, keringat malam, sesak kronik dan didapatkan memiliki kerusakan paru kiri komplit. Keadaan pasien dalam kehamilan ditatalaksana dengan terapi oksigen jangka panjang untuk mengatasi desaturasi persisten Kesimpulan: Di samping pengawasan ketat, terapi oksigen jangka panjang dapat menjadi tatalaksana utama untuk kondisi hipoksia kronik pada kerusakan paru dalam kehamilan akibat infeksi lama TB-MDR untuk mencegah morbiditas dan mortalitas ibu dan janin, seperti gagal napas dan pertumbuhan janin terhambat (PJT).
Antiviral Treatment On Pregnancy With COVID-19 Infection : A Systematic Review
Authors: Simanjuntak Tigor Peniel , Kakerissa Angela Putri , Kurniawan Grady Ivan 
Published: March 2024

Objective to evaluate antiviral treatment, duration, and side effects on pregnant women based on gestational age and severity of COVID-19 infection. Method: a systematic review of antiviral treatment, duration, and side effects on pregnant women based on gestational age and severity of COVID-19 infection. Systematic review was conducted following the guidelines of the Preferred Reporting Items for Systematic Reviews and Meta-analysis (PRISMA) Statement. Result 948 papers accessed through Pubmed, Scopus, Science Direct, Cohcrane, and other with keywords “Antiviral”, “Pregnancy” “Pregnant” “Coronavirus” “COVID-19” “SARS-CoV-2”. Duplicate papers were excluded (n=302), topics and abstracts that do not meet the criteria (n=612), and 25 papers that did not meet the inclusion criteria. 9 papers that meet the inclusion criteria (case reports and cohort retrospective case study) discussed 20 pregnant women with COVID-19 infection (16 moderate and severe cases received Remdesivir, 3 moderate and mild cases received Lopinavir-ritonavir combination, and 1 moderate case received Arbidol). Conclusion, remdesivir is an antiviral frequently used in pregnancy on trimester II and III with severe COVID-19 infection with a duration of treatment of 5-10 days. Remdesivir should be monitored because some show side effects of increasing liver function.Pengobatan Ibu Hamil yang Terinfeksi COVID−19 dengan AntivirusAbstrakTujuan untuk mengevaluasi penggunaan obat antivirus, lama pengobatan, dan efek samping pada wanita hamil dengan infeksi COVID-19 berdasarkan usia kehamilan dan derajat keparahan. Metode tinjauan literatur sistematis tentang penggunaan obat antivirus, lama pengobatan, dan efek samping pada wanita hamil dengan infeksi COVID-19 berdasarkan usia kehamilan dan tingkat keparahan. Tinjauan sistematis mengikuti pedoman dari Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA). Hasil terdapat 948 jurnal yang diakses melalui Pubmed, Scopus, Science Direct, Cohcrane dan lainya dengan kata kunci : Antiviral, Pregnancy, Pregnant, Coronavirus, COVID-19, SARS-CoV-2. Terdapat jurnal yang terduplikasi (n=302), topik dan abstrak yang tidak sesuai kriteria (n=612), dan 25 jurnal yang tidak sesuai kriteria inklusi. Terdapat 9 jurnal yang memenuhi kriteria inklusi (laporan kasus dan studi retrosepktif kohort) yang membahas 20 wanita hamil dengan infeksi COVID-19 (16 kasus dengan derajat sedang dan berat menerima Remdesivir, 3 kasus derajat sedang dan ringan menerima kombinasi Lopinavir-ritonavir, dan 1 kasus derajat sedang menerima Arbidol). Kesimpulan, remdesivir adalah antivirus yang sering digunakan pada wanita hamil trisemester II dan III dengan infeksi COVID-19 derajat berat, lama pengobatan 5-10 hari. Remdesivir harus diwaspadai karena dapat menimbulkan efek samping seperti peningkatan fungsi hati. Kata kunci: Antivirus, Hamil, COVID-19
Pola Kuman dan Kepekaan Antibiotik pada Kasus Infeksi Luka Operasi Obstetri
Authors: Irawan Iwan , Sukarsa M. Rizkar Arev , Aziz M. Alamsyah 
Published: March 2024

Tujuan: Mengetahui karakteristik pasien infeksi luka operasi (ILO) bidang Obstetri dan mendeskripsikan gambaran pola kuman serta kepekaan antibiotiknya di Rumah Sakit Umum Pusat (RSUP) Dr. Hasan Sadikin BandungMetode: Penelitian ini merupakan penelitian deskriptif observasional dengan pendekatan cross sectional yang bersifat retrospektif dari rekam medis pasien obstetri yang terdiagnosis infeksi luka operasi di RSUP Dr. Hasan Sadikin Bandung selama periode Juli 2020 - Juni 2021. Karakteristik subjek meliputi usia, berat badan, tinggi badan, body mass index (BMI), dan paritas. Dalam penelitian ini digunakan tingkat ketelitian (α) 5%, tingkat kepercayaan 95% sehingga diperoleh nilai Z = 1,96. Deskripsi karakteristik dan status pasien ditampilkan dalam bentuk tabel. Data kategorik dideskripsikan dengan jumlah (n) dan persentase (%).Hasil: Hasil penelusuran rekam medis didapatkan sebanyak 20 pasien yang didiagnosis dengan ILO. Seluruh pasien yang mengalami ILO merupakan pasien pasca seksio sesarea. Tidak didapatkan perbedaan yang bermakna pada rerata umur, berat badan, tinggi badan, BMI, dan sebaran paritas. Kesimpulan: ILO pada bidang obstetri seluruhnya terjadi pasca seksio sesarea. Tidak didapatkan perbedaan bermakna pada karakteristik pasien yang mengalami ILO. Pola kuman yang paling sering dijumpai adalah Escherichia coli dan Acinetobacter baumannii. Antibiotik yang sensitif terhadap mayoritas sampel adalah tigecycline dan meropenem.Antibiotic Susceptibility and Microbial Pattern in Obstetric Surgrical Wound InfectionAbstractObjective: To know the characteristics of surgical site infection (SSI) patients in obstetrics field and describing the microbial pattern and their antibiotic sensitivity at the Hasan Sadikin General HospitalMethod: This study was a descriptive observational study with a retrospective cross sectional approach from the medical records of obstetric patients diagnosed with surgical wound infections at Dr. Hasan Sadikin Bandung during the period July 2020 - June 2021. Subject characteristics include age, weight, height, body mass index (BMI), and parity. In this study, the level of accuracy (α) 5%, 95% confidence level, so that the value of Z = 1.96 is obtained. Results: The results gained from tracing medical records and obtained as many as 20 patients diagnosed with SSI. All patients who experienced SSI were post-cesarean section patients. There were no significant differences in the mean age, weight, height, BMI, and parity distribution. Conclusion: There was a high prevalence of female sexual dysfunction among health practitioners at Hasan Sadikin General Hospital, accounting to 41.8%. There was no statistically significant difference between various demographic aspects and female sexual dysfunction. Key words: Microbial pattern, antibiotic, sensitivity, surgical site infection
Hubungan Luaran Maternal dan Perinatal Terhadap Tingkat Keparahan Infeksi COVID-19
Authors: Fitraendi FM. Dicky , Hidayat Dini , Pramatirta Akhmad Yogi 
Published: March 2024

Tujuan: Penelitian ini dilakukan untuk mengetahui hubungan luaran maternal dan perinatal terhadap tingkat keparahan infeksi COVID-19 pada ibu bersalin di RSUP Dr. Hasan Sadikin Bandung.Metode: Penelitian ini menggunakan studi analitik observasional retrospektif dengan rancangan potong lintang menggunakan data rekam medik selama periode Maret 2020 hingga Juni 2021. Karakteristik subjek meliputi usia ibu, jumlah paritas, tingkat pendidikan, dan usia kehamilan. Luaran maternal meliputi hipertensi pada kehamilan, ketuban pecah dini, dan kejadian persalinan prematur. Hasil: Tidak ditemukan hubungan yang signifikan pada angka kejadian ketuban pecah dini (p-value 0,128) dan persalinan prematur (p-value 0,324) terhadap tingkat keparahan infeksi COVID-19. Pada ibu dengan infeksi COVID-19 derajat ringan memiliki luaran perinatal asfiksia ringan sebanyak 132 bayi (89,3%), asfiksia sedang 43 bayi (32,6%) dan asfiksia berat 5 bayi (3,8%). Terdapat hubungan bermakna antara derajat asfiksia pada janin dengan tingkat keparahan infeksi COVID-19 (p-value 0,013).Kesimpulan: Terdapat hubungan bermakna antara kejadian hipertensi dalam kehamilan dan tingkat mortalitas ibu terhadap tingkat keparahan infeksi COVID-19. Derajat asfiksia pada bayi baru lahir memiliki hubungan yang signifikan dengan tingkat keparahan infeksi COVID-19. Correlation Of Maternal And Perinatal Outcomes with the Severity Of Covid-19 InfectionAbstractObjective: This study was conducted to evaluate the relationship between maternal and perinatal outcomes with the severity of COVID-19 infection in women giving birth at Dr. Hasan Sadikin BandungMethods: This study was a retrospective observational analytical study with a cross-sectional design that used medical record data between March 2020 to June 2021. Subject characteristics include maternal age, parity, education level, and gestational age. Maternal outcomes consist of hypertension in pregnancy, premature rupture of membranes, and the incidence of preterm labor. Results: There was no significant relationship between the incidence of premature rupture of membranes (p-value 0.128) and preterm delivery (p-value 0.324) on the severity of COVID-19 infection. Mothers with mild COVID-19 infection had mild asphyxia perinatal outcomes as many as 132 infants (89.3%), moderate asphyxia in 43 infants (32.6%), and severe asphyxia in 5 infants (3.8%). There is a significant relationship between the degree of asphyxia in the fetus and the severity of COVID-19 infection (p-value 0.013).Conclusion: There is a significant relationship between the incidence of hypertension in pregnancy and maternal mortality with the severity of COVID-19 infection. The degree of asphyxia in newborns has a significant relationship with the severity of COVID-19 infection.Key words: Maternal outcome, perinatal, severity, COVID-19 infection
The Comparison of Peripheral Blood Morphology and Ferritin Level in Pregnancy Woman with Anemia Living in Lowland and Highland Areas
Authors: Amita Yulfa Rizki , Hartono Eddy , Syahrir Syahruni , Hamid Firdaus , Rambulangi Samrichard , Jusuf Elizabet Catherine 
Published: March 2024

Objective: Differences in the morphology features of red blood cells in population groups who live in the lowlands areas and the highlands areas will affect the diagnosis and appropriate therapies. Methods: The method used is a cross-sectional study of 75 pregnant women (6-38 weeks gestational age) with anemia living in highland and lowland areas found at Massenrempulu Hospital and Sitti Khadijah I Hospital. Anemia in pregnant women is diagnosed as a hemoglobin level less than 11gr/dl in the 1st and 3rd trimesters or less than 10.5 gr/dl in the 2nd trimester. The patient's blood sample was taken intravenously and performed serological and peripheral blood examination. Data were processed using the SPSS program, analyzed using univariate and multivariate tests.Results: In both results of the parametric and nonparametric test, ferritin levels showed a significant difference (p = 0.001), higher in the lowland areas group subjects (15.44 ± 36.92) compared to the highland areas group subjects (9.55 ± 30.16). There were no significant differences in morphology features (p> 0.05) between both groups.Conclusion: This study showed no significant differences in morphology features between the two groups. The lowland areas group subjects had a significantly higher ferritin level than that of the highland areas group subjects.Perbandingan Gambaran Morfologi Darah Tepi Pasien Gravid dengan Anemia Yang Tinggal di Pesisir Pantai dan Daerah PegununganAbstrakTujuan: Perbedaan ciri morfologi sel darah merah pada kelompok populasi yang tinggal di dataran rendah dan dataran tinggi akan mempengaruhi diagnosis dan terapi yang tepat.Metode: Metode yang digunakan adalah studi potong lintang pada 75 ibu hamil (usia kehamilan 6-38 minggu) dengan anemia yang tinggal di dataran tinggi dan dataran rendah yang ditemukan di RS Massenrempulu dan RS Sitti Khadijah I. Anemia pada ibu hamil didiagnosis berdasarkan kadar hemoglobin kurang dari 11gr/dl pada trimester I dan III atau kurang dari 10,5 gr/dl pada trimester II. Sampel darah pasien diambil secara intravena dan dilakukan pemeriksaan serologis dan darah tepi. Data diolah menggunakan program SPSS, dianalisis menggunakan uji univariat dan multivariat.Hasil: Pada hasil uji parametrik dan nonparametrik, kadar feritin menunjukkan perbedaan yang secara signifikan (p = 0,001), lebih tinggi pada subjek kelompok dataran rendah (15,44 ± 36,92) dibandingkan dengan subjek kelompok dataran tinggi (9,55 ± 30,16). Tidak ada perbedaan yang signifikan dalam morfologi darah tepi (p> 0,05) antara kedua kelompok.Kesimpulan: Penelitian ini tidak menunjukkan perbedaan morfologi yang signifikan antara kedua kelompok. Subyek kelompok dataran rendah memiliki kadar feritin yang jauh lebih tinggi dibandingkan dengan subjek kelompok dataran tinggi.Kata kunci: Morfologi darah tepi, kehamilan, anemia, dataran rendah, dataran tinggi
Hubungan Antara Indeks Massa Tubuh dan Paritas dengan Inkontinensia Urin Tipe Tekanan dan Desakan pada Lansia
Authors: Ridwan Farahdiba Aisyah Putri , Sinulingga Sadakata , Fauzi Amir , Putra Hadrians Kesuma , Putra Ridwan Abdullah 
Published: March 2024

Tujuan: Mengetahui hubungan antara IMT dan paritas dengan SUI dan UUI pada lansia. Metode: Penelitian observasional analitik dengan pendekatan desain cross sectional, penelitian ini menggunakan data primer yang diperoleh melalui wawancara menggunakan kuesioner untuk diagnosis inkontinensia urin (QUID).Hasil: Dari 64 responden lansia perempuan terdapat 26 yang mengalami SUI (40,6 %) dan 14 yang mengalami UUI (21,9%), terdapat hubungan yang signifikan antara IMT dengan SUI (p<0,05). Selain itu, paritas memiliki hubungan yang tidak signifikan dengan SUI (P>0,05, UUI memiliki hubungan yang tidak signifikan dengan IMT dan paritas (p>0,05). Kesimpulan: Terdapat hubungan yang signifikan antara IMT dan SUI.Kata kunci: IU, IMT, Paritas, Perempuan Lansia Association between Body Mass Indeks and Parity with Stress and Urgency Urinary Incontinence in the Elderly AbstractObjective: To find out the association between BMI and parity with SUI and UUI in the elderly. Method: This research was an analytic observational study with a cross sectional approach, This study used primary data obtained through interviews and uses the Questionnaire for Urinary Incontinence Diagnosis (QUID). Results: Data from 64 female elderly respondents showed that there was 26 female elderly with SUI (40,6%) and 14 with UUI (21,9%), there is a significant association between BMI for SUI (p<0,05). In addition, parity had no significant association with SUI (p>0,05). Meanwhile, UUI has no significant relationship with BMI and parity (p>0,05).Conclution: There was a significant association between BMI and SUI.Key words: UI, BMI, Parity, Elderly Women
COVID-19 Infection in Pregnancy Increases Length of Hospitalization and Need for Postpartum Intermediate Care
Authors: Susanto Slamet , Zulvayanti Zulvayanti , Nurdiawan Windi , Martaadisoebrata Djamhoer , Susiarno Hadi 
Published: March 2024

Objective: To find the prevalence and the outcomes of pregnant women with COVID-19 infection. Method: This was a cross-sectional study. The subjects were selected by total sampling. All pregnant women with COVID-19 infection and without COVID-19 infection who gave birth at Harapan Mulia Hospital from June 1, 2020 to August 31, 2021 with complete medical record data were recruited.Results: The average age of the patients with COVID-19 was 29.10 ± 7.325 years and the average age of the patients without COVID-19 was 29.24 ± 7.021 years. The average gestational age of pregnant women with COVID-19 was 37.52 ± 1.978 weeks and without COVID-19 was 38.14 ± 1.718 weeks. From the results of the statistical test of maternal outcomes, it was obtained that the P value for the length of hospitalization and type of treatment room after delivery was < 0.05, while the other variables were >0.05. For perinatal outcome analysis, from the results of statistical tests, it was obtained that P values for all variables were >0.05. Conclusion: There are differences in maternal outcomes and no differences in perinatal outcomes between pregnant women with COVID-19 and pregnant women without COVID-19 infection.Infeksi COVID-19 pada Kehamilan Meningkatkan Lama Rawat Inap dan Kebutuhan Ruang Intermediate Pasca PersalinanAbstrakTujuan: Mengetahui besarnya prevalensi dari ibu hamil dengan infeksi COVID-19 serta luarannya di RS Harapan Mulia BekasiMetode: analitik cross-sectionalHasil: Perbandingan demografi kelompok Ibu hamil dengan COVID-19, rata-rata usia pasien adalah 29,10 ± 7,325 tahun dan non COVID-19 29,24 ± 7,021 tahun. Rata-rata usia kehamilan ibu hamil dengan COVID-19 adalah 37,52 ± 1,978 minggu dan non COVID-19 adalah 38,14 ± 1,718 minggu. Dari hasil uji statistik luaran maternal, diperoleh nilai P pada lama perawatan dan jenis perawatan setelah persalinan lebih kecil dari 0,05 (nilai p < 0,05), sementara variabel lainnya lebih besar dari 0,05 (nilai p>0,05). Untuk analisis luaran perinatal, dari hasil uji statistik diperoleh nilai P pada semua variabel lebih besar dari 0,05 (nilai >0,05). Kesimpulan: Terdapat perbedaan luaran maternal dan tidak didapatkan perbedaan luaran perinatal antara kelompok ibu hamil dengan COVID-19 dan non COVID-19.Kata kunci: infeksi COVID-19, luaran maternal, luaran perinatal