bluuebunny/crossref_metadata_2025_split huggingface dataset:
Programs in the genre of investigative journalism on Russian TV-channels
Authors: Gegelova N. S. 
Published: March 2024

INTRODUCTION. The work presents a systematic review of investigative programs on Russian television channels and provides a generalized description of this area of journalism. In the last third of the 20th century, attention to mass media began to increase not only as a source of info rmation, but also as a channel of democratization, stimulating interest in investigative journalism an activity designed not only to illuminate the life of society, but also to involve public representatives from a variety of different backgrounds in this process. layers of the population.MATERIALS, METHODS, REVIEW. A review of television programs in the genre of investigative journalism is given based on the material of the leading federal Russian television channels “Channel One”, “Russia24”, “NTV”, emphasizing the relevance of their creation, the importance of refuting disinformation created in order to distort reliable information in the media, in including on television. In the process of working on the article, the author used the observation method, systematic and descriptive scientific methods. The article provides an overview of the most significant investigative television programs both in retrospect and from the perspective of modernity: “The View”, “Top Secret”, “Man and Law”, “Investigation of Eduard Petrov”, “New Russian Sensations”, “Anti-Fake”.RESULTS AND DISCUSSION. The results of the analysis of programs in the investigative genre showed that the genre of investigative journalism is relevant and in demand by viewers against the backdrop of an urgent need to refute obvious disinformation and lies created by countries unfriendly to Russia. This is fully confirmed by a study conducted by the Public Opinion Foundation among respondents aged 18 years and older (1500 people from urban and rural areas), conducted in 2023.CONCLUSION. The role of investigative journalism has increased significantly due to the escalation of the information war. Today, television offers a variety of types and forms of television programs in this genre, designed to orient viewers in the flow of information, help them recognize false news, and distinguish the truth from deliberate disinformation.
Parameters of the cognitive potential of educational text
Authors: Kashcheyeva A. V. 
Published: March 2024

INTRODUCTION. The subject of the study is the cognitive potential of educational text. The purpose of the study is to determine the parameters of the cognitive potential of an educational text that make up its conceptual model. The relevance of the study is explained by the insufficient knowledge of the cognitive characteristics of educational text as a means of cognitive activity.MATERIALS AND METHODS. To achieve the goal, the author analyzes theoretical and practical material using generalization, systematization and comparison and modeling methods. The research uses domestic and foreign research materials on the problem of academic training text and electronic English-language educational texts for teaching English.RESULTS AND DISCUSSION. The author uses the concept of cognitive potential to identify and summarize cognitive characteristics. The cognitive potential of educational text is understood as its ability to accumulate, store and transmit various types of knowledge in linguistic form. According to the notion, the a uthor proposes a model of the cognitive potential of the text, which includes three main parameters: the goal-oriented parameter, the subject-oriented parameter, and the text-oriented parameter.CONCLUSION. A conclusion is made about the relationship and heterogeneity of the parameters. It is noted that some parameters have a level structure, since the subjects of cognitive activity are the author and the addressee of the educational text, and the text parameter should be considered in conceptual and linguistic aspects. The development of research can complement and clarify the proposed model of the cognitive potential of educational text. The prospect is to study the relationship between knowledge formats, levels of knowledge in an educational text, as well as the study of cognitive and linguistic models and mechanisms of formation and representation of meaning.
Legal Protection for Child Victims of Bullying from the Perspective of Child Protection Law
Authors: Mayasari Dian Ety , Atjengbharata Andreas L. , Seguito Monteiro  
Published: March 2024

Legal protection for children has not been effective and there are still children who are victims of bullying. Bullying is an action that hurts the victim both physically and psychologically. The occurrence of bullying is a form of violation of children's rights which is regulated in the Child Protection Law, so perpetrators must be dealt with firmly by imposing criminal sanctions which are also regulated in the Child Protection Law. The purpose of this writing is to find out legal protection for children who are victims of bullying, especially repressive legal protection. It uses a normative juridical method that prioritizes primary legal material of the Child Protection Law. The final result is that the regulation of criminal sanctions in the Child Protection Law is cumulative and there are regulations for minimum and maximum criminal threats, so that judges in giving decisions on criminal sanctions can be minimal. This lack of firmness in setting sanctions does not provide a deterrent effect for perpetrators and other people who continue to carry out bullying actions against children.
Pengetahuan Siklus Hidup Nyamuk Aedes aegypti untuk Cegah DBD Bagi Warga RT 44 Kelurahan Guntung Manggis Banjarbaru
Authors: Muhamat Muhamat , Guawan Gunawan 
Published: March 2024

Abstract Dengue Hemorrhagic Fever (DHF) is still a health problem for the people of Banjarbaru. This disease can be prevented by avoiding the bite of the Aedes aegypti mosquito. The mosquito population of Ae. aegypti has a high potential to carry out biting activities. Therefore, mosquito control is the main focus in controlling DHF. The one house one larva monitor program by carrying out 3M activities (bury, cover and drain) water containers is relatively effective. However, knowledge about the life cycle is not the same among residents, so the implementation of this program is still constrained. With this background, the Lambung Mangkurat University Faculty of Mathematics and Natural Sciences service team held counseling for Dasa Wisma Jasmine 5 about the life cycle of the Aedes aegypti mosquito. The implementation of this service provides insight into the life cycle of the Aedes aegypti mosquito followed by the practice of trapping mosquito eggs. The hope of this program is to increase knowledge, change attitudes and take action in residential areas so that they do not become breeding grounds for the Aedes aegypti mosquito. Keywords: DHF disease; Aedes aegypti; knowledge; attitude; action
Proposal of a Course-Classification Support System Using Deep Learning and its Evaluation When Combined with Reinforcement Learning
Authors: Miyazaki Kazuteru , Yamaguchi Shu , Mori Rie , Yoshikawa Yumiko , Saito Takanori , Suzuki Toshiya 
Published: March 2024

The National Institution for Academic Degrees and Quality Enhancement of Higher Education (NIAD-QE) awards academic degrees based on credit accumulation.	These credits must be classified according to predetermined criteria for the selected disciplinary fields.	This study was conducted by subcommittees within the Committee for Validation and Examination of Degrees, the members of which should be well-versed in the syllabus of each course to ensure appropriate classification.	The number of applicants has been increasing annually, and thus, a course-classification system supported by information technology is strongly desired.	We proposed a course-classification support system (CCS) and an active CCS system for awarding degrees in NIAD-QE.	In contrast, in this study, we construct a CCS using deep learning, which has been significantly developed in recent years. We also propose a method “CLCNNwithXoL” combined with the reinforcement learning method.	We evaluate its effectiveness using the data submitted.
The Impact of Preoperative Medical Evaluation in an Orthopaedic Perioperative Medical Clinic on Total Joint Arthroplasty Outcomes
Authors: Veerareddy Rakesh R. , Panton Zachary A. , Zagaria Alexandra B. , Lites Christopher J. , Keeney Benjamin J. , Werth Paul M. 
Published: March 2024

Background:
A preoperative medical evaluation (PME) in total joint arthroplasty (TJA) is routine despite considerable variation and uncertainty regarding its benefits. The orthopaedic department in our academic health system established a perioperative medical clinic (PMC) to standardize perioperative management and to study the effect of this intervention on total hip arthroplasty (THA) and total knee arthroplasty (TKA) outcomes. This observational study compared the impact of a PME within 30 days prior to surgery at the PMC (Periop30) versus elsewhere (“Usual Care”) on postoperative length of stay (LOS), extended LOS (i.e., a stay of >3 days), and Patient-Reported Outcomes Measurement Information System-10 (PROMIS-10) Global Physical Health (GPH) score improvement in TJA.

Methods:
We stratified adult patients (≥18 years of age) who underwent primary TJA between January 2015 and December 2020 into Periop30 or Usual Care. We utilized univariate tests (a chi-square test for categorical variables and a t test for continuous variables) to assess for differences in patient characteristics. For both TKA and THA, LOS was assessed with use of multivariable negative binomial regression models; extended LOS, with use of binary logistic regression; and PROMIS-10 GPH score, with use of mixed-effects models with random intercept and slope. Interaction terms between the focal predictor (Periop30, yes or no) and year of surgery were included in all models.

Results:
Periop30 comprised 82.3% of TKAs (1,911 of 2,322 ) and 73.8% of THAs (1,876 of 2,541). For THA, the Periop30 group tended to be male (p = 0.005) and had a higher body mass index (p = 0.001) than the Usual Care group. The Periop30 group had a higher rate of staged bilateral THA (10.6% versus 7.5%; p = 0.028) and a lower rate of simultaneous bilateral TKA (5.1% versus 12.2%; p < 0.001) than the Usual Care group. Periop30 was associated with a lower mean LOS for both TKA (43.46 versus 54.15 hours; p < 0.001) and THA (41.07 versus 57.94 hours; p < 0.001). The rate of extended LOS was lower in the Periop30 group than in the Usual Care group for both TKA (15% versus 26.5%; p < 0.001) and THA (13.3% versus 27.4%; p < 0.001). There was no significant difference in GPH score improvement between Periop30 and Usual Care for either TKA or THA.

Conclusions:
Periop30 decreased mean LOS and the rate of extended LOS for TJA without an adverse effect on PROMIS-10 GPH scores.

Level of Evidence:
Therapeutic Level III. See Instructions for Authors for a complete description of levels of evidence.
Kemampuan Bercerita Anak Usia 5 Tahun (Aspek Semantik: Kajian Psikolinguistik)
Authors: Nisyah Khairun , Desmilianti Helvika , Susilo Susilo 
Published: March 2024

Penelitian ini bertujuan untuk mengetahui kemampuan bercerita pada anak berusia 5 tahun pada aspek struktur kalimat yang diujarkan anak dilihat dari kajian psikolinguistik. Anak Indonesia pada umumnya mendapat pendidikan formal pada usia 6 tahun. Maka antara umur 0 sampai 5 tahun anak lebih banyak berinteraksi dengan keluarga dan lingkungan sekitar. Pada saat itu pula proses pemerolehan Bahasa terjadi. Pendekatan penelitian yang digunakan adalah pendekatan kualitatif. Sumber data yang digunakan pada penelitian ini adalah rekaman suara anak berusia 5 tahun bernama Zubair. Teknik pengambilan data dilakukan dengan cara dialog atau wawancara untuk mengetahui kemampuan bercerita pada anak tersebut. Dalam hal ini, data yang diperolah adalah hasil rekaman yang ditranskrip untuk mendapatkan catatan tertulis dari subjek. Teknik analisis data yang digunakan yaitu melalui tiga alur tahapan yaitu reduksi data, analisis data, dan penarikan kesimpulan. Hasil penelitian menunjukan bahwa anak bernama Zubair memiliki kemampuan bercerita cukup baik. Terlihat dari pola kalimat yang utuh digunakan penutur. Dari aspek semantik, yang pertama Zubair mengalami tahap medan sematik. Dimana anak mampu mengelompokkan kata sesuai dengan medan semantik tersebut. Aspek kedua yang dialami Zubair yaitu tahap penyempitan makna, dimana tahap ini terjadi karena hasil dari pemikiran kritis seorang anak/manusia dalam bertutur. Hal ini dipengaruhi oleh lingkungan dan stimulasi yang diberikan orang tua untuk meningkatkan kemampuan berbahasa pada anak tersebut, dimana orang tua sering membacakan buku cerita kepada anak sejak anak masih bayi.
Pemanfaatan Media Pembelajaran Digital Pada Pembelajaran IPS Di Sekolah Dasar
Authors: Fitri Aisah Nur , Hadi Muhamad Sofian 
Published: March 2024

Di dunia pendidikan perkembangan IPTEK sangatlah di butuhkan. Dengan adanya perkembangan IPTEK proses pembelajaran akan semakin mudah untuk dilakukan dimana pun dan kapanpun. Peran guru di dunia pendidikan terutama dalam menghadapi perkembangan IPTEK sangatlah penting. Agar dapat menciptakan suasana belajar mengajar yang menyenangkan guru dapat menggunakan media pembelajaran dalam proses belajar mengajar. Media pembelajaran yang dapat digunakan salah satu contohnya ialah media pembelajaran berbasis digital. Metode yang digunakan pada penelitian kali ini yaitu metode kajian pustaka. Data pada penelitian berupa data dari studi literatur. Sumber data yang digunakan diperoleh dari berbagai referensi yang berhubungan dengan penelitian seperti buku, jurnal penelitian, dan buku panduan penggunaan beberapa platform digital. Teknik analisis data yang digunakan adalah analisis isi (content analysis), yaitu dengan melakukan pengkajian informasi yang dibahas, mengaitkan dengan setiap topik yang dibahas, kemudian pemetaan konsep dalam bentuk perbandingan dari setiap data penelitian. Hasil dari penelitian ini diharapkan memberi kontribusi dalam memudahkan sekolah, guru, dan siswa memanfaatkan beberapa platform digital yang dikeluarkan Kementerian Pendidikan dan Kebudayaan sebagai media pembelajaran.
Model Pembelajaran dan Gender Terhadap Hasil Belajar Peserta Didik Pada Mata Pelajaran Pendidikan Agama Islam
Authors: Rosyida Nadya Ilma , Isnaini Nurul Azizatul , Wulandari Reksahati , Kariadinata Rahayu , Malik Adam 
Published: March 2024

Mata pelajaran Pendidikan Agama Islam terkesan membosankan bagi beberapa siswa, maka guru PAI menerapkan beberapa model pembelajaran di kelas. Penelitian ini bertujuan untuk (1) menganalisis pengaruh model pembelajaran yang digunakan terhadap hasil belajar peserta didik pada mata pelajaran Pendidikan Agama Islam, (2) menganalisis pengaruh gender terhadap hasil belajar peserta didik pada mata pelajaran Pendidikan Agama Islam, (3) menganalisis keterkaitan antara model pembelajaran dan gender terhadap hasil belajar peserta didik pada mata pelajaran Pendidikan Agam Islam.Penelitian ini menggunakan pendekatan kuantitatif. Metode yang digunakan adalah ex post facto. Populasi pada penelitian ini adalah seluruh siswa di salah satu SMP di Kabupaten Pemalang. Sampel pada penelitian ini menggunakan teknik random sampling. Data bersumber dari dokumen berupa hasil belajar peserta didik dan dokumen sekolah. Statistic inferensial parametrik digunakan untuk mengambil kesimpulan terhadap suatu populasi dengan teknik uji hipotesis. Jenis perhitungannya adalah uji Anova Dua Jalur. Hasil penelitian menunjukkan bahwa tidak terdapat pengaruh antara model pembelajaran yang digunakan dan gender terhadap hasil belajar pada mata pelajaran Pendidikan Agama Islam siswa kelas IX pada salah satu SMP di Kabupaten Pemalang.
Insecticidal activity of isoborneol derivatives against Musca domestica adults and Culex quinquefasciatus larvae
Authors: BHAT SUJATA V. , Gupta Manisha O. , Pavela Roman , Kamath Chitra R. 
Published: March 2024

Abstract

Musca domestica L., a common housefly, and Culex quinquefasciatus mosquito are quite well-known pests that can transfer a wide range of diseases to humans as well as animals. In this study, various isoborneol derivatives including esters, ethers and thioethers were synthesized fromisoborneol under mild conditions. These derivatives were evaluated for inhibition of house-fly M. domestica adults and Cx. quinquefasciatus larvae. Two of the synthesized isoborneol ester derivatives (2 and 3) showed good activity against both insect species. Additional two derivatives (6 and 9) were active against M.domestica L. and the derivatives (1–3, 8) were active against Cx. quinquefasciatus larvae.
Causal relationship between telomere length and renal cell carcinoma and prognostic modeling of ccRCC based on telomere- related lncRNAs
Authors: Chen Hao , Zeng Jianfeng , Li Li 
Published: March 2024

Abstract

Background
Telomeres have been demonstrated to be critical in the development of multiple tumors. However, the association of telomere-related lncRNAs with clear cell renal cell carcinoma (ccRCC) and their prognostic roles in ccRCC patients remain unknown.
Methods
Exposure data was obtained from GWAS database. Two-sample mendelian randomization (MR) was used to test for causal associations between telomere length and renal cell carcinoma. Expression matrix and clinicopathological data of ccRCC patients were extracted from The Cancer Genome Altas and UCSC Xena browser. The differentially expressed genes were identified and intersected with the telomere-related genes downloaded from the Telnet database. Telomere-related lncRNAs were screened by the univariate Cox regression analysis. Each patient's risk score was calculated to establish a nomogram based on eight telomere-related lncRNAs screened by the least absolute shrinkage and selection operator (LASSO) algorithm and multivariate Cox regression analysis. The correlation between telomere-related lncRNAs and immune cells was assessed by the CIBEERSORT algorithm. The immune and stromal infiltrations were quantified by the ESTIMATE algorithm. Gene set enrichment analysis (GSEA) was performed to explore the selected lncRNA functions.
Result
A causal relationship between telomere length and renal cell carcinoma was observed. We screened eight telomere-related lncRNAs and established a risk score model for predicting survival in ccRCC patients. A nomogram was developed to predict the survival outcomes of postoperative patients by integrating several clinical factors, and a well-predictive effect was observed. The correlation between selected lncRNAs and immune function was explored by the CIBEERSORT and ESTIMATE algorithms. Besides, GSEA showed that telomere-related lncRNAs could affect ccRCC prognosis through multiple pathways.
Predictive Factors and Nomogram for 30-Day Mortality in Heat Stroke Patients: A Retrospective Case-Control Study
Authors: Li Anxin , Zhang Xiaoshi , Zhang Yuchen , Jiang Xiaoyan , Tao Yang , Chen Yan , Duan Zixiao , Wang Yadi , Deng Wuquan 
Published: March 2024

Abstract

Objective
This study aimed to identify early risk factors that impacted the 30-day mortality of heat stroke patients and establish a predictive model to assist clinicians in identifying the risk of death.
Methods
A retrospective case-control study was conducted, analyzing the clinical data of 72 patients with heat stroke admitted to Chongqing Emergency Medical Center between May 2016 and October 2023. The patients were divided into two groups to implement a control study: one comprising individuals who had died within 30 days of symptom onset, and the other consisting of those who had survived. The study analyzed the risk factors affecting 30-day mortality, plotted receiver operating characteristic (ROC) curves to evaluate patient’s mortality, and developed a model to predict the risk of death in heat stroke patients. The calibration curve and decision curve were used to evaluate the accuracy and clinical prediction efficiency of the nomogram.
Results
Within a 30-day period, 21 patients (29.167%) died. The APACHE II score, the ratio of lactate to albumin (Lac/Alb ratio), the core temperature at 30 minutes after admission were the independent risk factors for 30-day death in heat stroke patients. The area under the ROC curve for predicting mortality based on the APACHE II score was 0.820 (95% CI 0.716–0.924, P < 0.001). The best cut-off value was 29, with a sensitivity of 57.1% and a specificity of 92.2%. Moreover, the area under the ROC curve for predicting mortality based on the Lac/Alb ratio was 0.902 (95% CI 0.830–0.975, P < 0.001). The optimal cut-off value was 0.160, with a sensitivity of 90.5% and a specificity of 88.2%. The area under the ROC curve based on the core temperature at 30 minutes after admission was 0.700 (95% CI 0.544–0.855, P = 0.008). The optimal cut-off value was determined to be 39.5℃, with a sensitivity of 61.9% and a specificity of 80.4%. Finally, the area under the ROC curve for predicting death due to heat stroke using the combination of these three factors was 0.917 (95% CI 0.851–0.983, P < 0.001), with a sensitivity of 76.2% and a specificity of 92.2%.
Conclusion
The nomogram developed using these three indicators can be used in combination to predict 30-day mortality in heat stroke patients.
Circular RNA circFTO promotes pressure overload-induced cardiac hypertrophy via encoding a novel protein FTO-36aa
Authors: Xu Qi-rong , Liu Jin-long , Liu Zhi-bo , Zhu Rong-rong , Huang Huang , Li Yun-yun , Liu Ji-chun , Wu Qi-cai , Zhou Xue-liang 
Published: March 2024

Abstract

Background:
Pathological cardiac hypertrophy poses a significant threat to human health by leading to ventricular remodeling. CircRNAs play a potential role in the dysregulation of cardiac hypertrophy and recent evidence highlights their translational ability in various diseases. However, it remains unclear if circRNAs have a protein-coding role in myocardial hypertrophy and ventricular remodeling. This study aims to investigate the role of translatable circRNA in the pathogenesis of myocardial hypertrophy.
Methods:
The Transverse Aortic Constriction (TAC) induced hypertrophy mouse model was constructed. The heart function was evaluated by C57BL/6 mice. The myocardial structure injury and fibrosis were analyzed by HE staining and Masson staining. CircRNAs Microarray assay was used to screen the dysregulated circRNAs. The recombinant adenovirus-associated virus was constructed to over-expression or knockdown FTO or circFTO. Mass spectrometry analysis, Dual-luciferase reporter assay, and Polysome profiling analysis were performed to detect the circFTO encoded protein circFTO-36aa.
Results:
The study screened for dysregulated circRNAs in sham and transverse aortic constriction (TAC) and found that an up-regulated circular RNA, circFTO is generated from the back-splicing of FTO exon 5 and exon 7. Silencing circFTO by AAV significantly weakened the TAC-induced hypertrophy phenotype. Moreover, the study identified a novel protein, FTO-36aa, coded by circFTO that caused the pro-hypertrophy effect of circFTO. FTO-36aa promoted the ubiquitination-mediated protein degradation of FTO, which suppressed the demethylation of RNA, elevating the global m6A methylation. It was verified that the m6A reader, IGF2BP2, recognized the circFTO/FTO-36aa elevated m6A methylation and increased mRNA stabilities of m6A methylated hypertrophic genes.
Conclusion:
Overall, this study sheds light on the functional importance of alternative splicing-generated circFTO and its coded FTO-36aa during myocardial hypertrophy. The findings provide fundamental insights into the mechanisms of m6A methylation regulation in hypertrophic cardiomyocytes.