bluuebunny/crossref_metadata_2025_split huggingface dataset:
DELAYED RESPONSE TO SHOCKS IN THE NEO‐AUSTRIAN MODEL: CHARACTERISTICS OF THE TRAVERSE PATH
Authors: Nardini Franco 
Published: July 2006

ABSTRACTWe analyse the traverse path following either the introduction of a more profitable production technique or a rise in the wage rate on the assumption that investment depends, with a time lag, on the activity level of the economic system. We compare this case with the previously studied cases of an immediate reaction and, the opposite situation, an absence of reaction.We conclude by examining the case in which only some entrepreneurs are innovators.
A NON‐TRADABLE WAGE GOOD IN A RICARDIAN MODEL
Authors: Ho P. Sai‐wing 
Published: July 2006

ABSTRACTAn increasing cost in the provision of a non‐tradable wage good presents an obstacle to accumulation which cannot be bypassed through imports. An alternative solution involves channeling the landlords' rental income into subsidizing the production of the wage good. Simulation of the model yields results which suggest that this can postpone the arrival of the stationary state, albeit temporarily. The model seems to provide a framework for interpreting the housing policies of some small but populous East Asian countries. This could shed light on the role played by the government of those countries in fostering capital accumulation by dampening wage‐cost increases.
INTERNATIONAL PRODUCTION, INVESTMENT AND BORROWING WITH EXCHANGE RATE RISK AND FUTURES MARKETS
Authors: Broil Udo , Zilcha Itzhak 
Published: July 2006

ABSTRACTIn this paper we consider a multinational firm under exchange rate and interest rate risks in a multiperiod model. We analyze the impact of exchange rate uncertainty and the use of currency futures on the risk‐averse firm's decisions about home and foreign production. Without any hedging markets exchange rate risk lowers foreign investment and output. However, when futures markets exist, the separation property holds. Introducing another source of uncertainty, such as the interest rate, which is nondiversifiable, affects the production in both countries, i.e., the separation property does not hold. However, we show that the adverse effect of the missing financial market (to hedge against this additional risk) disappears when international borrowing is available.
PROFITS, INVESTMENT AND BUSINESS FLUCTUATIONS
Authors: van Ees Hans , Kuper Gerard H. , Sterken Elmer 
Published: July 2006

ABSTRACTIn this paper we analyze the impact of profits on investment in a simple Kaleckian investment model in which profits and capacity determine the level of investment. The analysis leads to the following conclusions. In the first place, the estimated impact of profits on investment behaviour in the Netherlands has diminished in the 1980s. The impact of the stock of capital on investment has remained constant in our sample period. In the second place, it can be observed that the impact of both profits and capital on investment is countercyclical. In periods of boom entrepreneurs prefer public capital markets as a source of investment funds, whereas in a recession they primarily rely on cheaper internal funds.
WEST GERMAN IDEAS ON EMPLOYMENT POLICY DURING THE FIRST YEARS OF THE ‘ECONOMIC MIRACLE’
Authors: Schefold Bertram 
Published: July 2006

ABSTRACTEmployment policies were a concern throughout history but not always in the sense of Keynes. German neoliberals (who had anticipated Keynesian ideas around 1930) emphasised the need for productive employment in the period of growth after the war. According to the vision of a social market economy, jobs should not be only temporary, but offer lasting employment, in industries with good development prospects, and in conditions conductive to good work.
The EADV story: how it came to be
Authors: Rothenborg Hans W. 
Published: July 2006

Abstract 1983 The concept of a European Academy is proposed in Athens by the Danish delegation. A preliminary review of Continuing Medical Education (CME) in Europe is decided. 1984 It is agreed to ask the national dermato‐venereological organizations in Europe if they will support the EADV idea economically and in practice. 1985 Support secured from most of the national societies and organizations. EADV is agreed name; Munich is suggested as administrative seat. A preliminary board is designated to finalize statutes and working principles. 1986 Statutes discussed and revised. EADV moved to Luxembourg. 1987 The official founding of EADV October 3 in “Bâtiment Jean Monet” in Luxembourg. Professor Emiliano Panconesi elected President and offers to organize 1st EADV Congress. 1988 Athens chosen as venue for 2nd EADV Congress. Nikolas Parissis becomes Presidentelect. 1989 Statutes amended to allow ordinary membership to all European dermato‐venereolo‐gists. 1st EADV Congress in Florence. Nikolas Parissis passed away after only one month in office. 1990 Board representation opened to other than EC countries if sufficient in the EADV and are recognized by the Board. Professor John Stratigos elected President and Copenhagen is chosen as venue for 3rd EADV Congress. 1991 An executive committee is formed. 2nd EADV Congress in Athens. 1986–89: Economic support from the dermato‐venereological organizations of the EC: 3 Sw.Frcs. per member per year.
Active sensitization caused by 2‐hydroxyethyl methacrylate, 2‐hydroxypropyl methacrylate, ethyleneglycol dimethacrylate and N,N‐dimethylaminoethyl methacrylate
Authors: Kanerva Lasse , Estlander Tuula , Jolanki Riitta 
Published: July 2006

AbstractA 45‐year‐old orthodontist became sensitized during patch tests with (meth)acrylates. Retesting showed that the sensitizing acrylics were methacrylates, namely 2‐hydroxyethyl methacrylate, 2‐hydroxypropyl methacrylate, ethylene glycol dimethacrylate and N,N‐dimethylaminoethyl methacrylate. Acrylates are stronger sensitizers than methacrylates, but the present report indicates that also methacrylates may sensitize at the patch test concentrations used. Accordingly, it may be necessary to use lower (meth)acrylate concentrations for patch testing.
Tissue expansion: update and prospects
Authors: Reali Umberto M. 
Published: July 2006

AbstractThis brief history of the development of the tissue expansion technique, from the initial intuitions of C.G. Neumann to the later applications by C. Radovan and subsequent uses, includes notes on the surgical techniques involved and the structural modifications of expanded skin. The author explains his preference for use of the external valve expander and presents data regarding use of high resolution ultrasound to monitor the thickness of expanded tissues. Dermatologists as well as surgeons should be familiar with the possible uses of this technique in the treatment of various wounds and skin lesions.
Treatment of fungal infections in HIV seropositive patients
Authors: Gazzard B.G. 
Published: July 2006

AbstractA significant minority of HIV‐positive patients presents with fungal infections. Such infections become increasingly common in the terminal stage of the disease. It is unclear why HIV‐positive individuals should be particularly susceptible to fungal infections. Several immune abnormalities, both humoral and cellular, may be involved. Other factors, including other skin conditions and their treatment, also may increase susceptibility. There is some evidence, in HIV‐positive patients, of autoimmunity and of abnormal reactions to fungal infection. These include seborrhoeic dermatitis, dermatophytoses, follicular dermatitis and candidosis. Buccal and oesophageal candidosis respond well to itraconazole, ketoconazole and fluconazole but rapidly relapse. Prophylaxis probably is not indicated, however, since symptomatic treatment quickly takes effect.
Tungiasis: report of a case *
Authors: Trevisan G. , Pauluzzi P. , Kokelj F. 
Published: July 2006

AbstractTungiasis is a cutaneous infestation caused by a small flea, Tunga penetrans. Tungiasis is commonly found in the equatorial and subtropical zones. With the increase in world travel, the disease is now reported in Europe, in individuals who have visited countries where the disease is endemic.
Is aphthous stomatitis associated with menstrual cycle in women?
Authors: McCartan Bernard E , Sullivan Aine 
Published: July 2006

AbstractObjective To establish the prevalence both of aphthae in women and of associations between aphthae and menstrual cycle.Background We believe that little valid evidence exists for associations between recurrent aphthae and menstrual cycle.Study Design Clients attending a well woman centre participated in a structured interview.Results Histories of aphthae were given by 6% of 1568 women. Histories of menstrual cycle associated aphthae were given by 0.6%. Twelve percent of a group of 213 aphthae sufferers gave histories of menstrual cycle associated aphthae, 8% with clear histories of premenstrual and/or menstrual aphthae.Conclusions A small proportion of women have clear histories of aphthae in the premenstrual period or during the menses.
Unusual presentation of pemphigus vulgaris
Authors: Bardazzi Federico , Guerra Liliana , Peluso Anna Maria , Piraccini Bianca Maria , Morelli Rossella 
Published: July 2006

AbstractWe report a case of a 50‐year‐old man who presented with a conjunctival erosion and lesions resembling acute paronychia of several fingers. The Tzanck preparation from the conjunctiva showed the presence of acantholytic cells. Skin biopsy showed suprabasal cleft formation with acantholysis. Direct immunofluorescence revealed intercellular epidermal staining with IgG and C3. Diagnosis of pemphigus vulgaris was therefore confirmed. Nail abnormalities that can be observed in pemphigus vulgaris are discussed.
Neural and vascular regulatory factors of the skin
Authors: Walsh David A. , Terenghi Giorgio , Polak Julia M. 
Published: July 2006

AbstractBackground Neural and vascular factors regulate many aspects of dermal function, including blood flow, inflammation, tissue repair and eccrine secretion. Abnormalities of neurovascular regulation may contribute to dermatological manifestations of a wide range of diseases including psoriasis, nodular prurigo and leprosy, diabetes mellitus and Raynaud's disease.Aims In this review we discuss evidence for roles played by neural and vascular regulatory factors in skin, with particular reference to the regulatory peptides substance P, calcitonin gene‐related peptide. vasoactive intestinal polypeptide, neuropeptide Y and endothelin and to the important endothelial cell product nitric oxide.Conclusions An understanding of the anatomical basis of neurovascular regulation and the changes which occur during disease may lead to novel diagnostic and prognostic tests for dermatological conditions, while an understanding of specific receptors mediating the actions of regulatory peptides will lead to the development of specific antagonists as a novel approach in clinical dermatology.
New approaches to the understanding of the pathogenesis of human papilloma induced anogenital lesions The role of co‐factors and co‐infection
Authors: Bernard Catherine , Mougin Christiane , Lab Michel 
Published: July 2006

AbstractHuman papiliomaviruses (HPVs) are recognized as likely viral agents responsible for genital precancer lesions and squamous cell cancers in both men and women. Nevertheless, their role in genital carcinogenesis is not entirely clear. This review aims to present current knowledge in experimental, biological and clinical work of diseases associated with HPV. There are many other agents, both non‐viral and viral, which might act synergistically or separately with HPV in a multistep tumorigenic process. This article suggests that other viral agents should be considered more fully.
CA15‐3(DF3) antibody reacts to normal sweat and sebaceous glands
Authors: Ando Iwao , Yasui Shoko , Kukita Atsushi , Hino Haruko 
Published: July 2006

AbstractAimTo study the localization of CA15‐3 antigen in normal skin.BackgroundCA15‐3 antigen can be useful in the investigation of skin appendages.MethodsSpecimens of paraffin embedded normal skin were stained by CA15‐3(DF3) monoclonal antibody.ResultsSebaceous glands and secretory segments of sweat glands were strongly positive.ConclusionsSkin appendages express CA15‐3 antigen in common with other epithelial gland tissues. This antigen is especially useful as a marker of the secretory segment of sweat glands.
Treatment of angiofibromas of tuberous sclerosis with carbon dioxide laser vaporization
Authors: Bajanca Rui , Leite Luiz 
Published: July 2006

AbstractThe therapeutic approach to angiofibromas in tuberous sclerosis is a challenge for the Dermatologist. The latest treatment modalities include use of argon and carbon dioxide lasers. We describe the ease of an 18‐year‐old Caucasian boy with multiple angiofibromas on the face, treated with CO2 laser with good cosmetic results.
Post‐erythema nodosum localized acquired hypertrichosis
Authors: Bardazzi Federico , Vincenzi Colombina , Stinchi Caterina , Tosti Antonella 
Published: July 2006

AbstractA 27‐year‐old woman presented with erythema nodosum on her legs. After treatment, only slight hyperpigmentation persisted at the sites of the previous erythema nodosum patches. Three months later the patient observed, at the same sites, the growth of dense tufts of fine black hairs.
The skin blanching assay with halcinonide, influence of halcinonide concentration and application time ⋆
Authors: Clarys Peter , Wets Laurens , Barel André , Gabard Bernard 
Published: July 2006

AbstractObjective Instrumental colour readings (Minolta Chromameter CR200) were performed in order to quantify corticosteroid induced skin blanching.Methods Different Halcinonide concentrations in the same vehicle ranging from 0.005% to 0.200% were tested on the volar part of the forearms. Besides dose‐response relationships we studied the influence of application time by applying the formulations under occlusion during 2, 12 and 18 h.Results All evaluated formulations provoked a discernible blanching as indicated by the significant increase of the L* parameter and the decrease of the a* parameter. Discrimination between the different Halcinonide concentrations was possible only in the 2 h application experiment. With longer application times a similar blanching was recorded for all Halcinonide concentrations.Conclusion Our results indicate that a shorter application time may lead to a more sensitive skin blanching assay.
Herpetiform Sweet's syndrome and leukaemia
Authors: Duguid C.M. , Otridge B. , Powell F.C. 
Published: July 2006

AbstractA patient who developed atypical vesicular Sweet's syndrome (SS) resembling herpes simplex virus infection, during relapse of acute myeloid leukaemia is presented. The morphologic and histologic spectrum of SS is discussed, alerting dermatologists to atypical varients. The association with malignancy, particularly of myeloprliferative origin, is highlighted, as are features of SS that suggest the presence of an underlying malignancy.
Raynaud's phenomenon with gangrene of the digits as the revealing sign of an antiphospholipid syndrome
Authors: Fiallo Paolo , Nunzi Enrico 
Published: July 2006

AbstractWe report the case of a 37‐year‐old woman who suffered for years of Raynaud's phenomenon associated with gangrene of digits. The patient displayed high levels of circulating antiphospholipid (aPL) antibodies, which on treatment with aspirin decreased significantly along with resolution of both Raynaud's phenomena and distal ischemic necrosis. To our knowledge this is the first report of an aPL syndrome featuring severe Raynaud's phenomenon as the only clinical sign. Possible pathogenetic correlations and the favourable therapeutic effect of aspirin are discussed.
Castleman's disease associated pemphigus. A form of paraneoplastic pemphigus
Authors: Vardy Daniel A. , Klapholz Laurent , Brautbar Chaim , Tambur Anat R. , Pisanty Sara , Rosenmann Eliezer , Ron Neomi , Goldenhersh Michael A. 
Published: July 2006

AbstractWe report a patient with Castleman's disease (angio‐follicular lymph node hyperplasia) associated with a pemphigus vulgaris‐Iike disorder. The patient had the hyaline‐vascular mediastinal type of Castleman's disease and developed painful oral erosions and penile lesions.Histologic examination revealed an interface dermatitis including vacuolar changes, necrotic keratinocytes and a lichenoid infiltrate. In addition there was suprabasal vesiculation with acantholysis, reminiscent of pemphigus vulgaris. Direct immunoperoxidase staining for intercellular igG was positive.HLA typing revealed that the patient did not have an HLA haplotype known to he associated with susceptibility to pemphigus.Until now, Castleman's disease Associated Pemphigus (CDAP) has been regarded as a unique entity presenting as atypical pemphigus vulgaris. However, a review of the literature reveals that the clinical and histologic signs of CDAP are virtually identical to those of paraneoplastic pemphigus and that both entities are associated with a lymphoproiiferative disorder. We suggest that CDAP is a form of paraneoplastie pemphigus.
Aggressive Kaposi's sarcoma associated with adenocarcinoma of the sigmoid in a woman without evidence of acquired immune deficiency syndrome
Authors: Mastrolonardo Mario , Loconsole Francesco , Conte Adele , Rantuccio Francesco 
Published: July 2006

AbstractWe describe the case of a 50‐year‐old Caucasian woman with Kaposi's sarcoma. After nearly 15 years of very benign course, a sudden exacerbation of the disease led to extensive involvement of the lower limbs and amputation of distal phalanxes of toes on the left foot. Of note, a previously overlooked adenocarcinoma of the sigmoid and oesophageal candidiasis were also detected in the absence of any obvious cause of immunosuppression.
Precursors of Langerhans cells
Authors: Misery Laurent , Dezutter‐Dambuyant Colette 
Published: July 2006

AbstractLC are dendritic cells localized in the supra‐basal layer of the epidermis and in mucous epithelia. Their density ranges from 200 to 900 cells/mm2. Their first function is to take an antigen, process it and present the processed antigen to the lymphocytes ([1] Misery L. La cellule de Langerhans. Editions Techniques, Encycl. Méd. Chir. Dermatologie 1994;12‐220‐B‐10). They are involved in numerous diseases.The origin of these cells has been debated but a consensus has now been reached. Langerhans cells (LC) were first described in 1868 by Paul Langerhans ([2] Über die Nerven der menschlichen Haut. Virch Arch A (Pathol Anat) 1868;44:325–337). He thought that it was a nerve cell. LC were first considered to be a component of the nervous system because their dendritic processes are similar so nerve fibers and because of their staining by gold chloride. Other authors have discussed a possible relationship with melanocytes. LC were regarded either as melanocytes, the progeny of melanocytes after division, or as melanocytes in an arrested stage of development ([3] Masson P. My conception of cellular naevi. Cancer 1951;4:9–15; [4] Fan J, Schoenfeld RJ, Hunter J. A study of the epidermal clear cells with special reference to their relationship to the cells of Langerhans. J Invest Dermatol 1959;32:445–450; [5] Zelickson AS. Granule formation in the Langerhans cell. J Invest Dermatol 1966;47:498–502). S100 protein is expressed on melanocytes, on nerve cells and on LC ([6] Cocchia D, Michetti F, Donato R. Immunochemical and immunocytochemical localization of S100 antigen in normal human skin. Nature 1981;294:85–87), but this does not imply that there is a common lineage. Subsequent research showed that this cell is in fact an immune cell.Electron microscopy has given us a new and very important insight into the nature of LC. Thus, there is no tonofilament, no desmosome and no melanosome ([7] Birbeck MS, Breathnach AS, Everall JD. An electron microscopy study of basal melanocyte and high level clear cell (Langerhans cell) in vitiligo. J Invest Dermatol 1961;37:51–63). The most important ultrastructural feature is the presence of Birbeck granules. Many experiments have pointed to a hone‐marrow origin of LC and their probable relationship with the phagocytic mononuclear cell system.
Growth inhibition of human keratinocytes by MC903 (calcipotriol) is linked to dephosphorylation of retinoblastoma gene product
Authors: Kobayashi Teruaki , Hashimoto Koji , Yoshikawa Kunihiko 
Published: July 2006

AbstractAim This paper compares the effects of MC903 (calcipotriol) and 1,25‐dihydroxyvitamin D3[1,25(OH)2D3; calcitriol] on differentiation and proliferation of normal human keratinocytes cultured in serum‐free medium. In order to understand the inhibitory mechanism of MC903, we examined its effect on cell cycle kinetics and the phosphorylation of retinoblastoma gene product (pRB), a tumor suppressor gene products, in normal human keratinocytes.Background The hormonally active form of vitamin D3, 1,25‐dihydroxy vitamin D3 [1,25(OH)2D3], regulates the differentiation and proliferation of epidermal keratinocytes in vitro. MC903 is a novel vitamin D3 analogue which is at least 100 times less potent than 1,25(OH)2D3 in its effects on calcium homeostasis.Methods We analyzed cell differentiation and cell cycle by flow cytometry using a FACScan, and pRB phosphorylation by Western blotting and densitometer.Results MC903 induced growth inhibition and differentiation of human keratinocytes. Cell cycle analysis demonstrated that 10‐6 M of MC903 induced cell cycle arrest in both G1/G0 (62.4 ± 0.7% versus 56.5 ± 1.7% in control, p < 0.01) and G2 + M (19.2 ± 0.3% versus 14.0 ± 0.9% in control, p < 0.01) phase. 10‐6 M of MC903 also increased the depnosphorylated pRB from 25% at 0 h to 84% at 48 h, as well as 1,25(OH)2D3.Conclusions Since pRB phosphorylation is supposed to be essential for the progression from G1 to S phase, the inhibition of pRB phosphorylation could be responsible for the G1/G0 growth arrest induced by MC903 in normal human keratinocytes.
Immunosuppression‐induced porokeratosis of Mibelli: complete regression of lesions upon cessation of immunosuppressive therapy
Authors: Gilead L. , Guberman D. , Zlotogorski A. , Vardy D.A. , Klaus S.N. 
Published: July 2006

AbstractPorokeratosis developing subsequent to immunosuppressive therapy is a common and well recognized phenomenon. A previously reported case of porokeratosis showed complete remission of the lesions following discontinuation of immunosuppression. A second example of porokeratosis is presented, in which lesions appeared 2 years after bone marrow transplantation, and completely regressed after immunosuppressive therapy was stopped.
Zosteriform persistent acantholytic dermatosis and porphyria cutanea tarda
Authors: Calista Donate , Feletti Stefano , Landi Giorgio 
Published: July 2006

AbstractOur case refers to a 77 year‐old man with a history of porphyria cutanea tarda (PCT) who presented with pruritic eruption consisting of erythematous papules localized in a zosteriform area on the right part of the trunk which had appeared three years previously. He gave a history of long exposure to the sun. A biopsy showed a spongiotic pattern, dyskeratotic acantholytic cells and corp ronds in the granular layer. Diagnosis of persistent acantholytic dermatosis (Grover's disease) was made. To the best of our knowledge no case of association of PCT and persistent Grover's disease has been previously described in the dermatologic literature.