bluuebunny/crossref_metadata_2025_split huggingface dataset:
The ‘missing’ in the ‘endgame’ of hepatitis C elimination: A qualitative study in New South Wales, Australia
Authors: Treloar Carla , Lancaster Kari , Rhodes Tim , Lafferty Lise , Bryant Joanne , Rance Jake 
Published: April 2024

AbstractIntroductionAfter a promising start in Australia, elimination efforts for hepatitis C are not on track. Following the global campaign to ‘find the missing’ in hepatitis C response, this qualitative study explores stakeholder perspectives on the ‘missing’ in the ‘endgame’ of hepatitis elimination in the state of New South Wales, Australia.MethodTwenty‐eight key informants working in New South Wales, elsewhere in Australia and internationally in high income countries participated in a semi‐structured qualitative interview. Analysis examined key informant accounts of the ‘missing’ in efforts to eliminate hepatitis C.ResultsParticipants' accounts framed the missing in relation to epidemiological knowledge, making‐up four population categories ‘missing’ or ‘missed’ in hepatitis C response. In turn, accounts situated the missing in relation to where and how individuals were presumed to connect, or not, with existing health‐care infrastructures. This gave rise to concerns about the capacity of health services to be made available for those at risk or in need, with systems said to create opportunities for people to ‘miss out’ on hepatitis C services.Discussion and ConclusionsThe ‘missing’ in the ‘endgame’ of hepatitis C elimination effort is not simply a function of who—populations missed—but of where and how, that is, situation and context. Our findings encourage a focus on how services, systems and contexts may create situations in which people become missed or are ‘made missing’ from care. We therefore advocate for a systemic, and not only population‐based, approach in the final push towards hepatitis C's elimination.
Green media coverage and corporate green innovation
Authors: Gao Jie , Wu Huiying , You Jiaxing , Smith Meg 
Published: April 2024

AbstractWe examine the effect of media coverage of corporate environmental activities on corporate green innovation. Using a large sample of corporate news coverage over the period 2001–2019, we find a positive relationship between green media coverage and the green innovation of a corporation but a negative one between nongreen media coverage and green innovation. These results are robust to a battery of sensitivity tests, including the instrumental approach and propensity score matching method. We examine and verify two well‐documented general channels through which the media influences corporate behaviors, namely, the financial constraint mitigation and external governance. More importantly, we examine channels specifically related to green media coverage and find that green media coverage strengthens the effect of pressure imposed by the government and the public for green innovation. Taken together, our results suggest that the media plays a distinctive role in green innovation through its particular attention to the environment.
Knockout of miR396 genes increases seed size and yield in soybean
Authors: Xie Hongtao , Su Fei , Niu Qingfeng , Geng Leping , Cao Xuesong , Song Minglei , Dong Jinsong , Zheng Zai , Guo Rui , Zhang Yang , Deng Yuanwei , Ji Zhanbo , Pang Kang , Zhu Jian‐Kang , Zhu Jianhua 
Published: April 2024

ABSTRACTYield improvement has long been an important task for soybean breeding in the world in order to meet the increasing demand for food and animal feed. miR396 genes have been shown to negatively regulate grain size in rice, but whether miR396 family members may function in a similar manner in soybean is unknown. Here, we generated eight soybean mutants harboring different combinations of homozygous mutations in the six soybean miR396 genes through genome editing with clustered regularly interspaced palindromic repeats (CRISPR)/CRISPR‐associated nuclease (Cas)12SF01 in the elite soybean cultivar Zhonghuang 302 (ZH302). Four triple mutants (mir396aci, mir396acd, mir396adf, and mir396cdf), two quadruple mutants (mir396abcd and mir396acfi), and two quintuple mutants (mir396abcdf and mir396bcdfi) were characterized. We found that plants of all the mir396 mutants produced larger seeds compared to ZH302 plants. Field tests showed that mir396adf and mir396cdf plants have significantly increased yield in growth zones with relatively high latitude which are suited for ZH302 and moderately increased yield in lower latitude. In contrast, mir396abcdf and mir396bcdfi plants have increased plant height and decreased yield in growth zones with relatively high latitude due to lodging issues, but they are suited for low latitude growth zones with increased yield without lodging problems. Taken together, our study demonstrated that loss‐of‐function of miR396 genes leads to significantly enlarged seed size and increased yield in soybean, providing valuable germplasms for breeding high‐yield soybean.
En tránsito por el norte de Chile: Desplazamiento forzado de población venezolana bajo el control fronterizo y sanitario durante la pandemia por COVID‐19 (2020‐2021)
Authors: Liberona Concha Nanette , Rodríguez Romina Ramos , Rivera Carlos Piñones , Ramírez Marioly Corona 
Published: April 2024

AbstractIn 2020, as a result of border closures due to the COVID‐19 pandemic, thousands of forcibly displaced migrant families, mainly of Venezuelan origin, entered Chile through unauthorized crossings. In response, the Government activated administrative measures to restrict mobility and promoted the militarization of the border. Although these measures did not limit people's entry, they were threatened by illegal collective expulsions and by a “humanitarian” intervention that aggravated the crisis. In this context, we explore through a collaborative ethnography, how the control of cross‐border mobility is linked to and reinforced by the health control of this population, threatened by the international border order. Specifically, we illustrate the effects of transit density on displaced persons, based on the management of the “migratory crisis” through the “Colchane Plan,” and we analyze the humanitarian response as a form of government that invisibilizes and naturalizes serious consequences on the health of bodies in mobility.
Sulphate resistance of low‐clinker engineered cementitious composites examined by MicroXRF imaging
Authors: Szeto Connor , Kurtis Kimberly E. 
Published: April 2024

AbstractEngineered cementitious composites (ECC) are a class of high‐performing fibre‐reinforced cementitious materials recognised for their increased ductility and durability compared to conventional cement‐based materials, owing to their autogenously controlled tight crack widths, even when subjected to high strains. To reduce ECC's environmental impact, this research examines the use of a low‐clinker binder − limestone‐calcined clay cement (LC3) − as an alternative to portland cement (PC), along with fly ash to further reduce the clinker proportion and the embodied CO2 of the formulations. In conventional concrete, LC3 hydrates to a denser microstructure resulting from the synergistic reaction between limestone and calcined clay. At the lower water contents typical of ECC and with the presence of fly ash, the influence of the binder composition on the microstructure is difficult to anticipate.To examine the influence of these compositional variables on microstructure, permeability and durability, the sulphate resistance of LC3‐based ECC is explored. Specifically, the ECC‐LC3 blends are designed with high clinker replacement rate of 75% by mass of binder and contain either conventional fly ash or reclaimed fly ash at 50% by mass of binder. Expansion of ECC‐LC3 samples subjected to standard sodium sulphate test conditions was measured up to 12 months and the depth of penetration of sulphates into the ECC‐LC3 of varying compositions was quantified using micro‐X‐Ray Fluorescence (microXRF) imaging and modelling. The expansion results show that the ECC‐LC3 formulations performed better than the PC samples and can provide adequate resistance to external sulphate attack, even when reclaimed fly ashes are used in place of the conventional ash. In addition, the shallow penetration of sulphate into these cementitious composites demonstrates the low diffusion coefficients values that were determined using the quantitative data from MicroXRF imaging.
Genetic insight into a polygenic trait using a novel genome‐wide association approach in a wild amphibian population
Authors: Toli Elisavet‐Aspasia , Kemppainen Petri , Bounas Anastasios , Sotiropoulos Konstantinos 
Published: April 2024

AbstractBody size variation is central in the evolution of life‐history traits in amphibians, but the underlying genetic architecture of this complex trait is still largely unknown. Herein, we studied the genetic basis of body size and fecundity of the alternative morphotypes in a wild population of the Greek smooth newt (Lissotriton graecus). By combining a genome‐wide association approach with linkage disequilibrium network analysis, we were able to identify clusters of highly correlated loci thus maximizing sequence data for downstream analysis. The putatively associated variants explained 12.8% to 44.5% of the total phenotypic variation in body size and were mapped to genes with functional roles in the regulation of gene expression and cell cycle processes. Our study is the first to provide insights into the genetic basis of complex traits in newts and provides a useful tool to identify loci potentially involved in fitness‐related traits in small data sets from natural populations in non‐model species.
FREQUENCY, PHASES AND CHRONOLOGY OF ROCK ART: SPATIOTEMPORAL STUDIES OF THE ALTA ROCK CARVINGS, NORTHERNMOST EUROPE
Authors: Gjerde Jan Magne 
Published: April 2024

SummaryThe rock art of Alta, comprising more than 7000 rock carvings, is dated by shoreline chronology. It is unparalleled in Europe. The well‐dated rock carvings make the material suitable for a temporal study of the rock art and the frequency of rock art production over c.5500 years. Based on new detailed elevation measurements performed by Alta Museum of the 92 panels with rock art and individual measurements of a total of 442 individual figures it is possible to discuss the temporal and spatial distribution of the rock art in Alta in detail. This up‐to‐date study shows that the rock art in Alta was made between c.5300 BC and AD 100 (6300–1900 BP). This raises the question whether the rock art record represents an even production of figures, accumulated gradually over more than five millennia, or whether there were more intensive phases of activity in the Alta area. Further, were all main areas used throughout the five millennia or did activities shift in the landscape? Based on the current record, the frequency of the rock art argues for a clear division of the material into four chronological phases. The material record shows an intense production in the earliest period from c.5300–4000 BC, with about 60% of the rock art being made then. The results from this study indicate that the rock carvings in Alta support a framework for the Alta rock art into four phases.
Successful prediction of left bundle branch block‐induced cardiomyopathy and treatment effect by artificial intelligence‐enabled electrocardiogram
Authors: Dhawan Rahul , Omer Mohamed , Carpenter Caitlin , Friedman Paul A. , Liu Xiaoke 
Published: April 2024

AbstractBackgroundLeft bundle branch block (LBBB) induced cardiomyopathy is an increasingly recognized disease entity. However, no clinical testing has been shown to be able to predict such an occurrence.Case reportA 70‐year‐old male with a prior history of LBBB with preserved ejection fraction (EF) and no other known cardiovascular conditions presented with presyncope, high‐grade AV block, and heart failure with reduced EF (36%). His coronary angiogram was negative for any obstructive disease. No other known etiologies for cardiomyopathy were identified. Artificial intelligence‐enabled ECGs performed 6 years prior to clinical presentation consistently predicted a high probability (up to 91%) of low EF. The patient successfully underwent left bundle branch area (LBBA) pacing with correction of the underlying LBBB. Subsequent AI ECGs showed a large drop in the probability of low EF immediately after LBBA pacing to 47% and then to 3% 2 months post procedure. His heart failure symptoms markedly improved and EF normalized to 54% at the same time.ConclusionsArtificial intelligence‐enabled ECGS may help identify patients who are at risk of developing LBBB‐induced cardiomyopathy and predict the response to LBBA pacing.
Functional substrate mapping of atrium in patients with atrial scar: A novel method to predict critical isthmus of atrial tachycardia
Authors: Yorgun Hikmet , Coteli Cem , Kılıç Gül Sinem , Aytemir Kudret 
Published: April 2024

AbstractAtrial tachycardia (AT) is a common rhythm disorder, especially in patients with atrial structural abnormalities. Although voltage mapping can provide a general picture of structural alterations which are mainly secondary to prior ablations, surgery or pressure/volume overload, data is scarce regarding the functional characteristics of low voltage regions in the atrium to predict critical isthmus of ATs. Recently, functional substrate mapping (FSM) emerged as a potential tool to evaluate the functionality of structurally altered regions in the atrium to predict critical sites of reentry. Current evidence suggested a clear association between deceleration zones of isochronal late activation mapping (ILAM) during sinus/paced rhythm and critical isthmus of reentry in patients with left AT. Therefore, these areas seem to be potential ablation targets even not detected during AT. Furthermore, abnormal conduction detected by ILAM may also have a role to identify the potential substrate and predict atrial fibrillation outcome after pulmonary vein isolation. Despite these promising findings, the utility of such an approach needs to be evaluated in large‐scale comparative studies. In this review, we aimed to share our experience and review the current literature regarding the use of FSM during sinus/paced rhythm in the prediction of re‐entrant ATs and discuss future implications and potential use in patients with atrial low‐voltage areas.
2:1 electronic AV block due to inappropriate automatic post‐ventricular atrial refractory period extension
Authors: Crea Pasquale , Bellocchi Paolo , Cocuzza Federica , Micari Antonino , Oreto Lilia 
Published: April 2024

AbstractA 16‐year‐old female with dual‐chamber pacemaker (Medtronic Azure XT DR), due to symptomatic third‐degree congenital atrioventricular (AV) block, presented to our ambulatory with dizziness and presyncopal episodes preceded by prodromes, occurring over the last few months. The device was programmed in DDD mode with an upper rate of 150 bpm. A head‐up Tilt Test (HUTT) revealed the unexpected emergence of 2:1 electronic AV block at a sinus rate of 130 bpm.
Martingale posterior distributions for cumulative hazard functions
Authors: Walker Stephen G. 
Published: April 2024

AbstractThis paper is about the modeling of cumulative hazard functions using martingale posterior distributions. The focus is on uncertainty quantification from a nonparametric perspective. The foundational Bayesian model in this case is the beta process and the classic estimator is the Nelson–Aalen. We use a sequence of estimators which form a martingale in order to obtain a random cumulative hazard function from the martingale posterior. The connection with the beta process is established and a number of illustrations is presented.
Anatomical classification of feline congenital extrahepatic portosystemic shunts based on CT angiography: A SVSTS and VIRIES multi‐institutional study in 231 cats
Authors: Weisse Chick , Asano Kazushi , Ishigaki Kumiko , Lipscomb Victoria , Llanos Cesar , Zwingenberger Allison L , Carroll Kenneth A , Grosso Federico R Vilaplana , Stock Emmelie , Buote Nicole , Aly Ali , Murgia Daniela , Arai Shiori , Linden Alex zur , Gordon Jana , Manassero Mathieu , Schwarz Tobias , Wallace Mandy L , Graham Julia , Hardie Robert , Chang Yifu , Robbins Mitch , Bismuth Camille , Karnia James , Sterman Allyson , Saunders Ashley , Montinaro Vincenzo , Guarnera Isabella , McLauchlan Gerard , Černá Petra , Maurin Marie‐Pauline , Aisa Josep , An Anjile 
Published: April 2024

AbstractThe prevalence of anatomical‐based subtypes of feline congenital extrahepatic portosystemic shunts (EHPSS) has not been completely elucidated. The goal of this study was to use CT angiography to create an anatomical‐based nomenclature system for feline congenital EHPSS. Additionally, subjective portal perfusion scores were generated to determine if intrinsic portal vein development was associated with different shunt conformations or patient age at the time of CT. The SVSTS and VIRIES list services were used to recruit cases. Data collected included patient DOB, gender, breed, weight, CT date, and reported diagnosis. Shunts were classified based upon (1) the shunt portal vessel(s) of origin, (2) the shunt systemic vessel(s) of insertion, and (3) any substantial portal vessels contributing to the shunt. Additionally, hepatic portal perfusion was subjectively scored between 1 (poor/none) and 5 (good/normal) based on the caliber of the intrahepatic PVs. A total of 264 CT scans were submitted from 29 institutions. Due to exclusion criteria, 33 (13%) were removed, leaving 231 CT scans to be included. Twenty‐five different EHPSS anatomies were identified with five classifications accounting for 78% of all shunts (LGP [53%], LGC‐post [11%], LCG [7%], LGC‐pre [4%], and PC [4%]). Shunt origin involved the left gastric vein in 75% of the described classifications. Significant differences were identified among the five most common shunt types with respect to age at the time of CT scan (P = .002), breed (P < .001), and subjective portal perfusion score (P < .001). This refined anatomical classification system for feline EHPSS may enable improved understanding, treatment comparisons, and outcome prediction for cats with these anomalies.
Synthesis and Study of Superhigh-Concentrated Organosols of Silver Nanoparticles
Authors: Vorobyev S. A. , Flerko M. Yu. , Novikova S. A. , Mazurova E. V. , Tomashevich Ye. V. , Likhatski M. N. , Saikova S. V. , Samoilo A. S. , Zolotovsky N. A. , Volochaev M. N. 
Published: April 2024

Abstract
Due to their unique properties, organosols of silver nanoparticles are widely used in optical and semiconductor devices, to produce electrically and thermally conductive films, as catalysts, antibacterial materials, etc. This work proposes a simple and highly productive method for the preparation of silver organosols, which have a metal concentration as high as 1800 g/L and contain spherical nanoparticles with low polydispersity and a median size of 9.1 nm. The method consists in the initial preparation of silver nanoparticle hydrosols with a concentration of higher than 30 g/L followed by the transfer of the NPs into an organic phase of o-xylene. A set of physical research methods has been employed to study the regularities of the extraction of silver nanoparticles with o-xylene in the presence of cetyltrimethylammonium bromide (CTAB) and ethanol and to determine the optimal process conditions, under which the extraction degree is as high as 62.5%. It has been found that bromine anions contained in CTAB molecules cause the aggregation of some amount of silver nanoparticles with the formation of silver metal sediment in the aqueous phase. According to X-ray photoelectron spectroscopy data, the sediment contains bromide ions (up to 4 at %) on the particle surface. Organosols synthesized under optimal conditions are stable for more than 7 months and withstand repeated cycles of drying and redispersing. Silver organosols have been used to obtain metal films with an electrical conductivity of about 68 500 S/cm, which increases to 412 000 and 509 500 S/cm (87.8% of the electrical conductivity of bulk silver) after thermal treatment at 150 and 250°C, respectively.
Slowly rotating Q-balls
Authors: Almumin Yahya , Heeck Julian , Rajaraman Arvind , Verhaaren Christopher B. 
Published: April 2024

AbstractQ-balls are non-topological solitons arising in scalar field theories. Solutions for rotating Q-balls (and the related boson stars) have been shown to exist when the angular momentum is equal to an integer multiple of the Q-ball charge Q. Here we consider the possibility of classically long-lived metastable rotating Q-balls with small angular momentum, even for large charge, for all scalar theories that support non-rotating Q-balls. This is relevant for rotating extensions of Q-balls and related solitons such as boson stars as it impacts their cosmological phenomenology.arXiv:2302.11589
Dynamics of inspiraling dark energy
Authors: Anguelova Lilia , Dumancic John , Gass Richard , Wijewardhana L. C. R. 
Published: April 2024

AbstractWe investigate the dynamics of a multifield dark energy model, which arises from certain rapid-turning and inspiraling trajectories in field space. We find the speed of sound $$c_s$$

c
s

of the dark energy perturbations around the background and show that $$c_s$$

c
s

is monotonically decreasing with time. Furthermore, it has a positive-definite lower bound that implies a certain clustering scale. We also extend the previously known background solution for dark energy to an exact solution that includes matter. This allows us to address the implications of our model for two cosmological tensions. More precisely, we argue that the $$\sigma _8$$

σ
8

tension can be alleviated generically, while reducing the Hubble tension requires certain constraints on the parameter space of the model. Notably, a necessary condition for alleviating the Hubble tension is that the transition from matter domination to the dark energy epoch begins earlier than in $$\Lambda $$
Λ
CDM.
Constraints on the trilinear and quartic Higgs couplings from triple Higgs production at the LHC and beyond
Authors: Stylianou Panagiotis , Weiglein Georg 
Published: April 2024

AbstractExperimental information on the trilinear Higgs boson self-coupling $$\kappa _3$$

κ
3

and the quartic self-coupling $$\kappa _4$$

κ
4

will be crucial for gaining insight into the shape of the Higgs potential and the nature of the electroweak phase transition. While Higgs pair production processes provide access to $$\kappa _3$$

κ
3

, triple Higgs production processes, despite their small cross sections, will provide valuable complementary information on $$\kappa _3$$

κ
3

and first experimental constraints on $$\kappa _4$$

κ
4

. We investigate triple Higgs boson production at the HL-LHC, employing efficient Graph Neural Network methodologies to maximise the statistical yield. We show that it will be possible to establish bounds on the variation of both couplings from the HL-LHC analyses that significantly go beyond the constraints from perturbative unitarity. We also discuss the prospects for the analysis of triple Higgs production at future high-energy lepton colliders operating at the TeV scale.