bluuebunny/crossref_metadata_2025_split huggingface dataset:
Implementation of medication reviews in community pharmacy: reaching consensus on stakeholders’ recommendations for mechanisms of change using the nominal group technique
Authors: Michel Dorothee E. , Tonna Antonella P. , Dartsch Dorothee C. , Weidmann Anita E. 
Published: March 2024

Abstract
Background
Since 2022, patients with five or more medicines are eligible for a medication review (MR) in a community pharmacy remunerated by the German health system. However, implementation has been slow, with few pharmacies providing MRs. Stakeholders’ input is necessary to detail how implementation strategies can be executed effectively on a national level. Prior research identified “external facilitation” and “altering incentives” as crucial strategies to achieve implementation outcomes.

Aim
To gather stakeholders’ recommendations for, and obtain consensus on, mechanisms of change that allow implementation strategies to work in practice.

Method
The consensus method used was the nominal group technique (NGT) with NGT-discussions held separately with pharmacy owners and pharmacy chambers employees. Votes were summed and the relative importance (rI) calculated, defined as (score achieved for a mechanism)/(maximum possible score) × 100. Content analysis provided context for the highest ranked mechanisms and allowed linking to implementation outcomes.

Results
Four NGT-discussions were held in 2023 (n = 2 owners; n = 2 chamber employees) with a total of 17 participants. The overall highest ranked mechanisms were fit-for-purpose software (rI = 154.7) detailed process support (rI = 104.9) and an expert support line (rI = 77.7). These together with financial viability (rI = 40.0) were prioritised by both participant groups. Three mechanisms were favoured for both implementation strategies, namely software, process support and materials (rI = 34.3).

Conclusion
This study identified stakeholders’ priorities for mechanisms of change to implement MRs in community pharmacies. Focusing efforts on the prioritised mechanisms is likely to significantly advance a national implementation plan for countries which are at an early implementation stage.
Towards understanding the crystallization of photosystem II: influence of poly(ethylene glycol) of various molecular sizes on the micelle formation of alkyl maltosides
Authors: Müh Frank , Bothe Adrian , Zouni Athina 
Published: March 2024

AbstractThe influence of poly(ethylene glycol) (PEG) polymers H–(O–CH2–CH2)p–OH with different average molecular sizes $$p$$
p
on the micelle formation of n-alkyl-β-D-maltoside detergents with the number of carbon atoms in the alkyl chain ranging from $$10$$

10

to $$12$$

12

is investigated with the aim to learn more about the detergent behavior under conditions suitable for the crystallization of the photosynthetic pigment–protein complex photosystem II. PEG is shown to increase the critical micelle concentration (CMC) of all three detergents in the crystallization buffer in a way that the free energy of micelle formation increases linearly with the concentration of oxyethylene units (O–CH2–CH2) irrespective of the actual molecular weight of the polymer. The CMC shift is modeled by assuming for simplicity that it is dominated by the interaction between PEG and detergent monomers and is interpreted in terms of an increase of the transfer free energy of a methylene group of the alkyl chain by 0.2 kJ mol−1 per 1 mol L−1 increase of the concentration of oxyethylene units at 298 K. Implications of this effect for the solubilization and crystallization of protein–detergent complexes as well as detergent extraction from crystals are discussed.
Mathematical modeling and problem solving: from fundamentals to applications
Authors: Ohue Masahito , Sasayama Kotoyu , Takata Masami 
Published: March 2024

AbstractThe rapidly advancing fields of machine learning and mathematical modeling, greatly enhanced by the recent growth in artificial intelligence, are the focus of this special issue. This issue compiles extensively revised and improved versions of the top papers from the workshop on Mathematical Modeling and Problem Solving at PDPTA'23, the 29th International Conference on Parallel and Distributed Processing Techniques and Applications. Covering fundamental research in matrix operations and heuristic searches to real-world applications in computer vision and drug discovery, the issue underscores the crucial role of supercomputing and parallel and distributed computing infrastructure in research. Featuring nine key studies, this issue pushes forward computational technologies in mathematical modeling, refines techniques for analyzing images and time-series data, and introduces new methods in pharmaceutical and materials science, making significant contributions to these areas.
Appraisal of Chitosan-Coated Lipid Nano-Combination with Miltefosine and Albendazole in the Treatment of Murine Trichinellosis: Experimental Study with Evaluation of Immunological and Immunohistochemical Parameters
Authors: Ibrahim Asmaa F. , Selim Sahar M. , Shafey Dalia A. , Sweed Dina M. , Farag Shaimaa A. , Gouda Marwa A. 
Published: March 2024

Abstract
Purpose
Resistance and adverse consequences of albendazole (ABZ) in treating trichinellosis urged demand for secure and effective new drugs. The current study aimed to assess the effect of chitosan-coated lipid nano-combination with albendazole and miltefosine (MFS) in treating experimental murine trichinellosis and evaluating pathological and immunological changes of trichinellosis.

Materials and Methods
One hundred twenty Swiss albino mice were divided into six groups. Each group was subdivided into a and b subgroups based on the scarification time, which was 7- and 40-days post-infection (PI), respectively. The treatment efficacy was evaluated using parasitological, histopathological, serological (interleukin (IL)-12 and IL-4 serum levels), immunohistochemical (GATA3, glutathione peroxidase1 (GPX1) and caspase-3), and scanning electron microscopy (SEM) methods.

Results
The most effective drug was nanostructured lipid carriers (NLCs) loaded with ABZ (G5), which showed the most significant reduction in adults and larval count (100% and 92.39%, respectively). The greatest amelioration in histopathological changes was reported in G4 treated with MFS. GATA3 and caspase-3 were significantly reduced in all treated groups. GPX1 was significantly increased in G6 treated with MFS + NLCs. The highest degenerative effects on adults and larvae by SEM were documented in G6.

Conclusion
Loading ABZ or MFS on chitosan-coated NLCs enhanced their efficacy against trichinellosis. Although ABZ was better than MFS, their combination should be considered as MFS caused a significant reduction in the intensity of infection. Furthermore, MFS showed anti-inflammatory (↓GATA3) and antiapoptotic effects (↓caspase-3), especially in the muscular phase. Also, when loaded with NLCS, it showed an antioxidant effect (↑GPX1).

Graphical abstract
Build Plate Roughness Study on Part Bonding for the Laser Powder Bed Fusion Process
Authors: Ruiz-Huerta Leopoldo , Correa-Gómez Erasmo , Castro-Espinosa Homero , Caballero-Ruiz Alberto 
Published: March 2024

AbstractAdditive manufacturing (AM) processes have emerged as valuable partners in conventional manufacturing, facilitating the production of low-batch components with complex geometries across diverse industries. However, despite ongoing advancements in various AM technologies, consistently achieving reliable and defect-free components remains a challenge. In powder metal AM, the use of substrates or build plates to support the entire build plays a crucial role in ensuring build stability. Build plate preparation typically involves surface grinding followed by finishing sanding, leading to variations in surface roughness between different manufacturing runs. This study aimed to elucidate the bonding characteristics at the build plate-part interface by investigating the porosity and build plate-part strength at different substrate surface roughness. To this end, a multi-roughness build plate was designed and fabricated for tensile testing via laser powder bed fusion (LPBF) processing of upright specimens. The specimens were subjected to computed tomography (CT) scans for porosity assessment, followed by tensile tests to evaluate the mechanical performance at the build plate-part interface (bp-p). CT inspection revealed no porosity at the interface for any roughness level. Furthermore, analysis of the tensile behavior in relation to substrate roughness (Ra values of 0.8 μm, 1.4 μm, 3.5 μm, and 4.4 μm) did not reveal statistically significant differences.
Research on curriculum resources in mathematics education: a survey of the field
Authors: Rezat Sebastian 
Published: March 2024

AbstractThis survey describes the structure of the field of research on curriculum resources in mathematics education in the period from 2018 till 2023. Based on the procedures of a systematic review relevant literature was identified using Web of Science as a database. The included literature was analyzed and categorized according to the type of curriculum resource and the area of study. Seven areas of studies were identified: studies on the role of curriculum resources, content analysis, user studies, studies on the effects of curriculum resources, studies on curriculum resource design, curriculum resources as data, and reviews. The areas were further subdivided into different subcategories based on the research questions of the included papers. The findings show that research on mathematics textbooks is still predominant in the field. The most popular areas of research are content analysis, user studies, studies on design, and studies on effects. Emerging areas are research on students’ use of curriculum resources and the employment of user data from digital curriculum resources as data basis in mathematics education research.
Corpse or not? Two peculiar cases of misidentification
Authors: Plenzig S. , Helmus J. , Weber M. , Verhoff M. A. , Hachmann V. 
Published: March 2024

SummaryIrrespective of whether they are intended for collectors or for the fetish market, dolls are being produced to look more and more realistic with such a degree of life-like detail that they can be mistaken for a real person. This paper reports two cases of misidentification due to this increasing similarity: In the first case, a sex doll was mistaken for a corpse; in the second case, a corpse was mistaken for a doll. While in the latter case, only medical laypersons were at the discovery site, in the first case, an emergency doctor had issued a medical certificate of death for the purported corpse. The medicolegal examiner who was subsequently called to the scene could still rectify the misconception on-site. Mistakes of this nature are likely rare phenomena. It, however, remains to be seen if the increasingly life-like appearance of dolls on the one hand, and the increasingly doll-like appearance of some people, e.g., through cosmetic surgery, will lead to a rise in such cases. To avoid misidentification as in the first reported case, it is essential to prepare medical students well for the task of performing a primary external postmortem examination; it is equally important that fully-trained doctors regularly refresh their expertise in this respect.
Reliability and validity of the Turkish version of the thirst distress scale-heart failure
Authors: Yakar Hatice Karabuga , Oguz Sıdıka , Waldreus Nana 
Published: March 2024

AbstractObjective: Patients with heart failure may experience thirst distress. There is, however, no measurement tool to define patients’ thirst distress in Turkey. The study aimed to determine psychometric properties of the translated Turkish version of the Thirst Distress Scale-Heart Failure (TDS-HF) in a sample of heart failure patients. Design: This methodologically planned study was conducted in two different training and research hospitals in Istanbul. Content validity, confirmatory factor analysis and concurrent validity were used in the validity analysis following the language validity analysis. Reliability coefficients were analysed by calculating Cronbach’s alpha, McDonald’s Omega and test-retest reliability coefficients. Validity and reliability analysis involved 116 patients, and test-retest analysis was carried out among 36 patients who volunteered to participate in the study. Results: The patients had a mean age of 55.2 ± 14.9. The factor structure and the examined fit indices of the one-dimensional eight-item scale indicated that the Turkish version of the scale was consistent with the original model. Item-total correlations were between 0.84 and 0.93, Cronbach’s alpha coefficient was 0.90, the test-retest reliability coefficient was 0.97 and the McDonald’s omega coefficient was 0.93, demonstrating that the scale is highly reliable. Conclusion: The Turkish version of the Thirst Distress Scale-Heart Failure was found to be valid and reliable.
Simple and Rapid Characterization of Sarawak Stingless Bee Honey Using Melissopalynological and ATR-FTIR Analysis
Authors: Bong Zhang Ru , Shah Rohan Mahendra , Chee Xavier Wezen , Hwang Siaw San , Ginjom Irine Runnie Henry 
Published: March 2024

AbstractStingless bee honey (SBH) is gaining popularity for its unique flavour and potential nutritional and health benefits. Due to its low yield, SBH is usually more expensive than common honey. Moreover, SBH is also commonly sold as raw honey with higher moisture content, which could jeopardize its shelf life, quality, and safety if not stored properly. Therefore, a rapid method is required to characterize stingless bee honey for authentication and quality assurance. This study aimed to categorize SBH samples from Sarawak using two simple and rapid methods, namely the pollen or melissopalynological analysis and attenuated-total-reflectance Fourier-transform-infrared (ATR-FTIR). The melissopalynological analysis showed that all honey samples analyzed are multifloral honey. Principal Component Analysis (PCA) on the ATR-FTIR spectra clearly illustrated a clear separation between normal honey and SBH; and between raw SBH and processed SBH. Overall, this study provides important insights into the characterization of SBH from Sarawak using two simple and rapid methods. Further research could expand on these findings and contribute to the development of the SBH industry in Malaysia.
Ancient diversity within Diporodrilus (Crassiclitellata, Annelida) clarify the historical biogeography of Corso-Sardinian earthworms
Authors: Marchán Daniel F. , Navarro Alejandro Martínez , Gérard Sylvain , Decaëns Thibaud , Novo Marta 
Published: March 2024

AbstractCorsica and Sardinia are amongst the largest islands of the Western Mediterranean. Their complex geological history included belonging to the European–Iberian continental margin (close to current-day Catalonia and Provence) and varying degrees of isolation for the last 30 million years, leading to peculiar, highly endemic faunas and floras. This is especially true for their earthworm faunas, which include endemic species of several Lumbricoidea genera and the endemic family (or subfamily) Diporodrilidae. Only three species have been described for the morphologically unique Diporodrilus, but there exists evidence for wide morphological variability within them and the existence of several species-level genetic lineages within Corsica. This work aimed to investigate the genetic diversity and phylogenetic relationships between the genetic lineages of Diporodrilus from Corsica and Sardinia (based on the sequences of 5 mito-nuclear markers), to perform an integrative systematics revision combining species delimitation techniques and morphological data, and to obtain a time-calibrated phylogeny of Diporodrilus and other Corso-Sardinian Lumbricoidea. Within 15 populations of the morphospecies Diporodrilus omodeoi and Diporodrilus pilosus across Corsica and Sardinia, 10 species-level genetic lineages were detected. Phylogenetic independence, high genetic divergence and morphological differences provided the support for the description of five new pseudocryptic species: Diporodrilus rotundus sp. nov., Di. jorgei sp. nov., Di. minor sp. nov., Di. meridionalis sp. nov. and Di. telti sp. nov. Time-calibrated phylogenetic inference estimated the age for genus Diporodrilus at 65.9 Mya; even if other Corso-Sardinian genera were significantly younger, all of them presented deep divergences predating the break-off of the microplate from the continent. The almost threefold increase in the known diversity of Diporodrilus stresses the need for comprehensive earthworm diversity inventories in both Sardinia and Corsica, and for studies on their ecological role and conservation status. The close correspondence between some geological and cladogenetic events suggest that the distribution of Corso-Sardinian earthworms could be used to inform standing geological controversies.
Spatial Indexicals
Authors: Stokke Andreas 
Published: March 2024

Abstract
This paper offers a theory of spatial indexicals like here and there on which such expressions are variables associated with presuppositional constraints on their values. I show how this view handles both referential and bound uses of these indexicals, and I propose an account of what counts as the location of the context on a given occasion. The latter is seen to explain a wide range of facts about what the spatial indexicals can refer to.
COVID-19 outbreak among employees of a German hospital: risk factor analysis based on a follow-up questionnaire and seroprevalence
Authors: Kosenkow Jennifer , Ankert Juliane , Baier Michael , Kesselmeier Miriam , Pletz Mathias W. 
Published: March 2024

Abstract
Background
The Co-FriSero study describes a COVID-19 outbreak at the Friedrichroda hospital in Thuringia, Germany, with 185 beds and 404 employees, at the onset of the pandemic between March 30th, 2020, and April 13th, 2020. This study aimed to analyze potential sources of SARS-CoV-2 transmission amongst hospital employees.

Methods
After the outbreak, a comprehensive follow-up was conducted through a questionnaire and a seroprevalence study using two different immunoassays for IgG detection and a third for discordant results.

Results
PCR screenings confirmed SARS-CoV-2 infection in 25 of 229 employees, with an additional 7 detected through serology. Statistical analysis indicated that direct patient contact, exposure to high flow ventilation in non-isolated rooms, direct contact with colleagues, shared use of recreational rooms, and carpooling were associated with an increased infection risk. Conversely, contact with family and friends, public transportation, public events, and use of locker rooms were not associated with infection. Male gender showed a lower infection likelihood, independent of age and other risk factors.

Conclusion
This study highlights the role of direct patient care and internal staff interactions in the spread of SARS-CoV-2 in the hospital setting. It suggests that non-traditional transmission routes like carpooling require consideration in pandemic preparedness.
Improving Equipment Effectiveness through Visual Stream Mapping: Some Exploratory Research Findings in the Ready-Made Garment (RMG) Sector
Authors: Aziz Alberuni , Talapatra Subrata , Belal H. M. 
Published: March 2024

AbstractImproving equipment effectiveness is crucial for flexible manufacturing, ensuring that machines and tools perform their functions efficiently and consistently. Our study aimed to enhance the Overall Equipment Effectiveness (OEE) in Bangladesh’s Ready-Made Garments (RMG) manufacturing system. We used the DMADV methodology incorporating Visual Stream Mapping (VSM) and OEE. By utilising VSM, we identified issues, eliminated them in the design phase, and evaluated performance in the verification phase. We automated the material handling system to reduce handling time, and the result was a significantly improved OEE in the automated manufacturing system compared to the manual one. This study has numerous benefits in flexible manufacturing and operations management, from immediate efficiency improvements to long-lasting organisational cultural transformations. Thus, it’s a noteworthy topic for practical applications and research. Enhancing Equipment Effectiveness through Visual Stream Mapping 4.0 has broad-reaching implications, including improved productivity, reduced waste, increased efficiency, better resource utilisation, and a more agile and responsive manufacturing environment. Although OEE and VSM are frequently used separately in different manufacturing systems, this study’s novelty lies in their combined application within garment manufacturing.
New approach for satellite DEM accuracy enhancement by combing machine learning, fuzzy majority voting, and weighted interpolation techniques
Authors: Kandil Walaa Metwaly , Zarzoura Fawzi H. , Salah Mahmoud , El-Mewafi Mahmoud 
Published: March 2024

AbstractThe digital elevation model (DEM) is crucial in many global and regional scientific studies in civilian and military applications. The aim of this research is to develop and test a new DEM approach for correcting the various errors in the Shuttle Radar Topography Mission (SRTM) digital elevation model. Firstly, the DEMs with the feature attributes from Sentinel-2 multispectral imagery are generated. Secondly, SRTM DEM with one band and attributes of a sentinel-2 image with eight bands are used as input data in supervised max-like hood, an artificial neural network (ANN), and support vector machine (SVM) classification models. Thirdly, ANN, supervised max-like hood, and SVM classification models, which have various properties, are fused by fuzzy majority voting (probability fusion). Finally, the fused probability is assigned for each pixel of the image, which has 12 fixed ground control points (GCPs), which is considered new input data for the inverse probability weighted interpolation (IPWI) approach to create the corrected SRTM elevations. The results were contrasted with a reference DEM (RD) created by image matching with Worldview-1 stereo satellite images, which had a 1-m vertical accuracy. The results of this study demonstrated that the RMSE of the original SRTM DEM was 5.95. On the other hand, the RMSE of the estimated elevations by the IPWI approach has been improved to 1.98 compared with that of the MLR method (3.01). The study shows a series of significant improvements in the SRTM when assessed with the reference DEM, with an RMSE reduction of (66.72%) when compared to the widely utilized multiple linear regression (MLR) method. It can be concluded that the elevation error of the original SRTM DEM is clearly reduced by the suggested approach.