bluuebunny/crossref_metadata_2025_split huggingface dataset:
The weekly P25 of the age of the influenza-like illness shows a higher correlation with COVID-19 mortality than rapid tests and could predict the evolution of COVID-19 pandemics in sentinel surveillance, Piura, Perú, 2021
Authors: Ocaña Gutiérrez Víctor Raúl , González Ramírez Rodolfo Arturo , Ocaña Aguilar Víctor Alexander , Ocaña Aguilar Nadia Gabriela , Holguín Mauricci Carlos Enrique 
Published: March 2024

Goal
To describe the dynamics of syndromic surveillance of ILI cases in seasonal and COVID-19 pandemic scenarios.

Methodology
A descriptive study of the epidemiological behavior of ILI in the seasonal and COVID-19 pandemic scenarios. Of a sample of 16,231 cases of ILI from 2013 to 2021, the features of cases from 68 weeks before and during the pandemic were selected and compared; weekly endemic channels were built; data fluctuations on the trend of ILI cases were analyzed; and estimated weekly correlations between weekly P25 age, cases confirmed by rapid tests, and mortality from COVID-19. To analyze clinical-epidemiological and mortality data, Student’s t test, Mann-Whitney U, Chi2, Spearman’s Ro, polynomial, and multinomial regression with a 95% confidence interval were used.

Results
During the COVID-19 pandemic, those most affected with ILI were: adults and the elderly; higher median age; autochthonous cases predominated; a lower proportion of other syndromes; delays in seeking care; and a higher rate of pneumonia attack than in the seasonal period (p< 0.01). Rapid tests (serological and antigenic) confirmed 52.7% as COVID-19. Two ILI pandemic waves were seasonally consistent with confirmed COVID-19 cases and district mortality with robust correlation (p<0.01) before and during the pandemic, especially the ILI weekly P25 age, which has a more robust correlation with mortality than ILI and rapid tests (p<0.01) whose endemic channels describe and could predict the evolution of the pandemic (p<0.01).

Conclusions
The pandemic changed the clinical and epidemiological behavior of ILI, and the weekly P25 of age is a more robust indicator to monitor the COVID-19 pandemic than a rapid test and could predict its evolution.
Planting the seeds for success: A qualitative study exploring primary healthcare providers’ perceptions about medical cannabis
Authors: Schuhmacher Sandi , Gaid Dina , Bishop Lisa D. , Fleming Laura , Donnan Jennifer 
Published: March 2024

Background
In Canada, cannabis legalization altered the way that the public can access cannabis for medical purposes. However, Canadians still struggle with finding healthcare professionals (HCPs) who are involved in medical cannabis counselling and authorization. This raises questions about the barriers that are causing this breakdown in care. Our study explored the perceptions of primary care providers regarding cannabis in their practice.

Methods
Semi-structured interviews were conducted by Zoom with HCPs in Newfoundland and Labrador (NL) to discuss their experiences with medical and non-medical cannabis in practice. Family physicians and nurse practitioners who were practicing in primary care in NL were included. The interview guide and coding template were developed using the Theoretical Domains Framework (TDF). A thematic analysis across the TDF was then conducted.

Results
Twelve participants with diverse demographic backgrounds and experience levels were interviewed. Five main themes emerged including, knowledge acquisition, internal influences, patient influences, external HCP influences, and systemic influences. The TDF domain resulting in the greatest representation of codes was environmental context and resources.

Interpretation
The findings suggested that HCPs have significant knowledge gaps in authorizing medical cannabis, which limited their practice competence and confidence in this area. Referring patients to cannabis clinics, while enforcing harm-reduction strategies, was an interim option for patients to access cannabis for medical purposes. However, developing practice guidelines and educational resources were suggested as prominent facilitators to promote medical cannabis authorization within the healthcare system.
Experiences of postpartum anxiety during the COVID-19 pandemic: A mixed methods study and demographic analysis
Authors: Mamrath Simran , Greenfield Mari , Fernandez Turienzo Cristina , Fallon Victoria , Silverio Sergio A. 
Published: March 2024

Introduction
The first wave of the COVID-19 pandemic saw the reconfiguration of perinatal and maternity services, national lockdowns, and social distancing measures which affected the perinatal experiences of new and expectant parents. This study aimed to explore the occurrence of postpartum anxieties in people who gave birth during the pandemic.

Methods
An exploratory concurrent mixed-methods design was chosen to collect and analyse the quantitative and qualitative data of an online survey during the first UK lockdown. The survey included the Postpartum Specific Anxiety Scale–Research Short Form–for use in global Crises [PSAS-RSF-C] psychometric tool, and open-ended questions in relation to changes in birth plans and feelings about those changes and giving birth in a pandemic. Differences in measured scores were analysed for the participant’s ethnicity, sexual orientation and disability using independent Student’s t-tests, and for age, the analysis was completed using Pearson’s correlation. Qualitative data from open-ended questions were analysed using a template analysis.

Results
A total of 1,754 new and expectant parents completed the survey between 10th and 24th April 2020, and 381 eligible postnatal women completed the psychometric test. We found 52.5% of participants reported symptoms consistent with a diagnosis of postnatal anxiety–significantly higher than the rates usually reported. Younger women and sexual minority women were more likely to score highly on the PSAS-RSF-C than their older or heterosexual counterparts (p<0.001). Younger participants reported anxieties in the ‘infant safety and welfare’ category, whilst lesbian, gay, bisexual, and pansexual participants scored highly in the ‘psychosocial adjustment to motherhood’ category.

Discussion
Postpartum anxiety is under-reported, and demographic differences in the rates of postpartum anxiety are under-researched. This research demonstrates for the first time a difference in postpartum anxiety rates amongst sexual minority women.
Awareness regarding breast cancer amongst women in Pakistan: A systematic review and meta-analysis
Authors: Abdul Rehman Muhammad , Tahir Erfa , Ghulam Hussain Huzaifa , Khalid Ayesha , Taqi Syed Mohammad , Meenai Eilaf Ahmed 
Published: March 2024

BackgroundBreast cancer (BCa) is the most common cause of cancer death in Pakistan. In 2019, Pakistan saw the highest global BCa-associated death rate. But do Pakistani women know about the various aspects of BCa? And how prevalent are BCa screening methods amongst Pakistani females? These questions formed the basis for our study.MethodsWe conducted this review in accordance with Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. On September 1, 2023, we searched PubMed, Embase, Scopus, and Google Scholar, and performed a citation search to search for eligible studies published in 2010 or after, using the following terms: “breast cancer” and “Pakistan”. Observational studies that evaluated BCa awareness and/or practice amongst Pakistani females who were not associated with medicine were eligible. We used the National Institutes of Health quality assessment tool to assess the risk of bias. We conducted a proportion meta-analysis to calculate pooled prevalences for variables.ResultsResponses from 9766 Pakistani women across 18 included studies showed alarmingly low levels of BCa knowledge: risk factors, 42.7% (95% CI: 34.1%-51.4%); symptoms, 41.8% (95% CI: 26.2%-57.5%); diagnostic modalities, 36.3% (95% CI: 23.1%-49.4%); treatments, 46.6% (95% CI: 13.5%-79.8%). Prevalence of breast self-examination (BSE) and ever having undergone a clinical breast exam (CBE) was 28.7% (95% CI: 17.9%-39.6%) and 15.3% (95 CI: 11.2%-19.4%), respectively. BCa knowledge was significantly associated with better educational status, age, and socioeconomic status.ConclusionOn average, only two in five Pakistani women are aware of one or more risk factors, symptoms, or diagnostic modalities. Approximately one in two women know about possible BCa treatment. Less than one in three women practice regular BSE, and less than one in five women have ever undergone a CBE.
Development of a multi-wear-site, deep learning-based physical activity intensity classification algorithm using raw acceleration data
Authors: Ng Johan Y. Y. , Zhang Joni H. , Hui Stanley S. , Jiang Guanxian , Yau Fung , Cheng James , Ha Amy S. 
Published: March 2024

Background
Accelerometers are widely adopted in research and consumer devices as a tool to measure physical activity. However, existing algorithms used to estimate activity intensity are wear-site-specific. Non-compliance to wear instructions may lead to misspecifications. In this study, we developed deep neural network models to classify device placement and activity intensity based on raw acceleration data. Performances of these models were evaluated by making comparisons to the ground truth and results derived from existing count-based algorithms.

Methods
54 participants (26 adults 26.9±8.7 years; 28 children, 12.1±2.3 years) completed a series of activity tasks in a laboratory with accelerometers attached to each of their hip, wrist, and chest. Their metabolic rates at rest and during activity periods were measured using the portable COSMED K5; data were then converted to metabolic equivalents, and used as the ground truth for activity intensity. Deep neutral networks using the Long Short-Term Memory approach were trained and evaluated based on raw acceleration data collected from accelerometers. Models to classify wear-site and activity intensity, respectively, were evaluated.

Results
The trained models correctly classified wear-sites and activity intensities over 90% of the time, which outperformed count-based algorithms (wear-site correctly specified: 83% to 85%; wear-site misspecified: 64% to 75%). When additional parameters of age, height and weight of participants were specified, the accuracy of some prediction models surpassed 95%.

Conclusions
Results of the study suggest that accelerometer placement could be determined prospectively, and non-wear-site-specific algorithms had satisfactory accuracies. The performances, in terms of intensity classification, of these models also exceeded typical count-based algorithms. Without being restricted to one specific wear-site, research protocols for accelerometers wear could allow more autonomy to participants, which may in turn improve their acceptance and compliance to wear protocols, and in turn more accurate results.
Transcriptome analysis reveals organ-specific effects of 2-deoxyglucose treatment in healthy mice
Authors: Wells Ann E. , Wilson John J. , Heuer Sarah E. , Sears John D. , Wei Jian , Pandey Raghav , Costa Mauro W. , Kaczorowski Catherine C. , Roopenian Derry C. , Chang Chih-Hao , Carter Gregory W. 
Published: March 2024

Objective
Glycolytic inhibition via 2-deoxy-D-glucose (2DG) has potential therapeutic benefits for a range of diseases, including cancer, epilepsy, systemic lupus erythematosus (SLE), and rheumatoid arthritis (RA), and COVID-19, but the systemic effects of 2DG on gene function across different tissues are unclear.

Methods
This study analyzed the transcriptional profiles of nine tissues from C57BL/6J mice treated with 2DG to understand how it modulates pathways systemically. Principal component analysis (PCA), weighted gene co-network analysis (WGCNA), analysis of variance, and pathway analysis were all performed to identify modules altered by 2DG treatment.

Results
PCA revealed that samples clustered predominantly by tissue, suggesting that 2DG affects each tissue uniquely. Unsupervised clustering and WGCNA revealed six distinct tissue-specific modules significantly affected by 2DG, each with unique key pathways and genes. 2DG predominantly affected mitochondrial metabolism in the heart, while in the small intestine, it affected immunological pathways.

Conclusions
These findings suggest that 2DG has a systemic impact that varies across organs, potentially affecting multiple pathways and functions. The study provides insights into the potential therapeutic benefits of 2DG across different diseases and highlights the importance of understanding its systemic effects for future research and clinical applications.
Perceived delivery of essential yoga properties within in-person and remote weight loss maintenance interventions
Authors: Sherman Sally A. , Quinn Tyler D. , Bock Beth C. , Braun Tosca D. , Unick Jessica L. 
Published: March 2024

Objectives
While previous research has utilized remote delivery of yoga interventions, no research has specifically interrogated the effectiveness of remote yoga intervention delivery. In this secondary analysis of weight-maintenance trial data, we examined participant perceptions of essential yoga properties across in-person and remote formats, hypothesizing that perceptions would not differ following remote delivery.

Methods
24 women with overweight or obesity (34.6±4.1 kg/m2, 48.2±9.9 years) received a 12-week Iyengar yoga intervention (2x/week) following a 3-month behavioral weight loss program. Of 23 participants who completed follow-up questionnaires, 12 received the planned in-person intervention and 11 received a remote intervention (delivered live) due to the COVID-19 pandemic. The Essential Properties of Yoga Questionnaire (EPYQ) was completed online by participants and by the instructors to measure the perceptions of the relative emphasis placed on the essential components of the yoga intervention via 14 subscales. Linear regression models were used to compare perceptions of each EPYQ dimension across in-person and remote delivery methods, as well as between participants and instructors, independent of delivery method.

Results
13 of the 14 subscales did not differ between delivery modalities (p>0.05). Participants perceived more individual attention within in-person yoga (p = 0.003). For both delivery methods, instructors perceived breathwork, restorative postures, and body locks to be incorporated to a lesser degree compared to participants (β = -1.28, p = 0.003; β = -1.57, p = 0.019; β = -1.39, p = 0.036; respectively). No other significant differences across the participant and instructor scores were observed.

Conclusions
Findings provide preliminary support for the use of live remote delivery of yoga, effectively communicating most essential yoga properties when compared to in-person classes. However, participants perceived more individual attention with in-person versus remote delivery; thus, future remote-based yoga interventions may benefit from providing additional individualized feedback.
Analyses of the European Union and its member states’ proposals on reforming the ISDS system under the UNCITRAL working group III
Authors: Khalique Muhammad Abdul 
Published: March 2024

The European Union and its member states back the formation of a permanent investment tribunal and a Committee of the Parties that would handle different tasks, including the selection of adjudicators. According to the European Union and its member states, the members of the investment tribunal should work on a full-time basis, and the selection criteria should prioritize the most qualified and unbiased individuals, regardless of their nationality. To expand the pool of potential adjudicators and promote diversity, they suggest adopting the entire language of Article 2 of the ICJ Statute for the qualifications requirements. The European Union and its member states do not support the idea of tribunal members being appointed by States that do not recognize the tribunal's authority.This paper delves into the European Union and its member States' positions on certain fundamental issues related to ISDS reform, along with a comprehensive analysis of varying positions held by other stakeholders, including some members of UNCITRAL working group III who share similar viewpoints with the European Union and its member states on some matters and have differing opinions on others.
Using imagery for acceptance and wellbeing in sport
Authors: Vealey Robin S. , Pacewicz Christine E. 
Published: March 2024

Abstract
The purpose of this article is to offer background and strategies to utilize mental imagery to enhance acceptance as a significant foundation for mental health and wellbeing in athletes. Sport possesses many threats to participants’ mental health and ability to flourish, including unrealistic expectations, pressure from others, and training demands. Although acceptance has been shown to be an important precursor to wellbeing, the prescribed culture of mental toughness in sport teaches athletes to be nonaccepting of mistakes and negative outcomes which often threaten their mental health. Athletes need to be educated and trained to practice acceptance as a strong, mature, mentally healthy response in terms of their self-perceptions, perceptions of others, and responses to external events. Mental imagery has a strong association with emotion and has been successfully used as an intervention technique to enhance physical and mental health. However, acceptance has not been an outcome of interest in most imagery interventions related to mental health, and future research on interventions to enhance acceptance is warranted. Some strategies and examples of using mental imagery to build acceptance and wellbeing are suggested.
Thermalization rate of polaritons in strongly-coupled molecular systems
Authors: Tereshchenkov Evgeny A. , Panyukov Ivan V. , Misko Mikhail , Shishkov Vladislav Y. , Andrianov Evgeny S. , Zasedatelev Anton V. 
Published: March 2024

Abstract
Polariton thermalization is a key process in achieving light–matter Bose–Einstein condensation, spanning from solid-state semiconductor microcavities at cryogenic temperatures to surface plasmon nanocavities with molecules at room temperature. Originated from the matter component of polariton states, the microscopic mechanisms of thermalization are closely tied to specific material properties. In this work, we investigate polariton thermalization in strongly-coupled molecular systems. We develop a microscopic theory addressing polariton thermalization through electron-phonon interactions (known as exciton-vibration coupling) with low-energy molecular vibrations. This theory presents a simple analytical method to calculate the temperature-dependent polariton thermalization rate, utilizing experimentally accessible spectral properties of bare molecules, such as the Stokes shift and temperature-dependent linewidth of photoluminescence, in conjunction with well-known parameters of optical cavities. Our findings demonstrate qualitative agreement with recent experimental reports of nonequilibrium polariton condensation in both ground and excited states, and explain the thermalization bottleneck effect observed at low temperatures. This study showcases the significance of vibrational degrees of freedom in polariton condensation and offers practical guidance for future experiments, including the selection of suitable material systems and cavity designs.
Pain coping and catastrophizing in youth with and without cerebral palsy
Authors: Vinkel Michael N. , Rackauskaite Gija , Østergaard John R. , Finnerup Nanna B. , Jensen Mark P. 
Published: March 2024

Abstract

Objectives
The aim of this study is to compare the use of pain coping strategies and pain catastrophizing in youth with and without cerebral palsy (CP), and to examine how these two groups differ with respect to the associations between pain coping, catastrophizing, and measures of psychological function and sleep disturbance.

Methods
Twenty-seven individuals with CP and 49 healthy controls aged 15–22 were included in this cross-sectional observational study. Pain was assessed using a semi-structured interviews and participants completed measures of pain coping, pain catastrophizing, psychological function, and sleep.

Results
Youth with CP used information seeking and problem solving (p = 0.003, Cohen’s d (d) = −0.80) and sought social support (p = 0.044, d = −0.51) less often, and used internalizing as a coping strategy more often (p = 0.045, d = 0.59) than healthy controls. The use of information seeking and problem solving correlated more strongly with measures of depression (p = 0.023, Cohen’s f (f) = 0.08) and sleep disturbance (p = 0.022, f = 0.08), while behavioral distraction correlated more strongly with measures of anxiety (p = 0.006, f = 0.11) and sleep disturbance (p = 0.017, f = 0.09) in youth with CP, compared to healthy controls.

Conclusions
The study findings raise the possibility that youth with CP may benefit more in terms of psychological function and sleep quality from coping training interventions that focus on behavioral distraction, information seeking, and problem solving. Research to test these ideas in additional samples of youth with CP is warranted.
Generalized Autoregressive Conditional Betas: A New Multivariate Score-Driven Filter
Authors: Blazsek Szabolcs , Jörding August , Rai Simran 
Published: March 2024

Abstract
In this paper, we extend the recent Gaussian autoregressive conditional beta (Gaussian-ACB) model from the literature on score-driven models. In the new asset pricing model, named the t generalized ACB (t-GACB) model, a multivariate score-driven filter for the t-distribution drives dynamic interaction effects among the beta coefficients. We present the econometric formulation and statistical inference for the t-GACB model, which we apply to 15 stocks from the United States (US) from 1999 to 2022. In our empirical application, we use the three Fama–French factors as asset pricing factors, and we also use the Volatility Index, TED Spread, and ICE BofA US High Yield Index Option-Adjusted Spread as exogenous explanatory variables that influence the beta coefficients. We compare the statistical and realized tracking error performances of the Gaussian-ACB, t-ACB, and t-GACB models, and we find that the t-GACB model improves the Gaussian-ACB model.