bluuebunny/crossref_metadata_2025_split huggingface dataset:
Public library websites for teenagers: How are they addressing the consumer health information needs of today's teens?
Authors: Burke Jennifer E. , Hughes‐Hassell Sandra 
Published: February 2009

AbstractYoung adult use of the Web both for creating and reviewing content continues to grow and the Internet has become an important tool for teenagers seeking health information (Borzekowski & Rickert 2001, Gray et al 2005; Rideout 2001; Richardson 2002; Vargas 2005). More than 70 percent of 15 to 17 year olds say they have used the Internet to look up health information (Rideout 2001, Richardson et al 2002). In fact, the Kaiser Family Foundation study reported in “Generation Rx.com” found that more youth had looked for health information than had engaged in various Web 2.0 behaviors as purchasing something online or using a chat room (Rideout 2001). Researchers cite availability, anonymity, and affordability as the key reasons teenagers turn to the web for answers to their health‐related questions (Barak & Fisher 2001; Gray et al 2005).While the Internet provides teenagers with access to a wealth of health‐related resources, it also presents challenges that can negatively impact the ability of adolescents to access quality information online. Difficulty conducting searches, judging the credibility of the information retrieved, and accessing sites due to filtering software are just a few of the barriers teenagers face (Gray et al 2002; Gray et al 2005; Richardson et al 2002). Like many Web users, teenagers also express concerns about privacy and confidentiality, especially in chat rooms or email correspondences (Vargas 2005).Given the issues teens face when searching for health information online, it seems natural that public libraries take the lead in providing assistance to teenagers who need help finding health information. Libraries, particularly public libraries, have a long history of providing consumer heath information to adults in their communities, and this service has transitioned online as libraries provide Internet access to electronic consumer health information (Smith 2006). In addition, many public libraries have developed websites specifically for teenagers. As more teens look for personalized information or the ability to ‘create’ their own content, these library web pages often serve as centers for reference, educational support, popular materials, community information, and library programming (Hughes‐Hassell & Miller 2003; Jones 1997). Including links to useful websites would alleviate some of the frustration teenagers face when searching for quality health information on the Internet and allow them to make their own informed decisions (Vargas 2005). But how common is it for these web pages to provide consumer health information for teenagers?
User research and testing of FRBR prototype systems
Authors: Zhang Yin , Salaba Athena 
Published: February 2009

AbstractThis study is part of a three‐year ongoing IMLS‐funded project on the research and development of FRBR‐based retrieval systems to support user tasks and to facilitate effective information seeking. The major focus of this study is on user research and testing of current FRBR prototype systems. A sample of three such FRBR prototypes are evaluated and compared by 72 users from both public and academic library settings. This user study will help identify useful options for FRBR implementation and contribute toward the development of more effective FRBR systems in the future. The findings of this study will also reveal current FRBR implementation issues and possible solutions from users' perspectives.
What exactly is an item in the digital world?
Authors: Floyd Ingbert R. , Renear Allen H. 
Published: February 2009

AbstractIFLA's Functional Requirements for Bibliographic Records (FRBR) is a model of the bibliographic universe. Although initially its application to the digital world appears to be straightforward, upon closer examination puzzles arise. One is that within the digital world it is surprisingly difficult to say exactly what FRBR items really are. On the one hand, the ontological candidates for items (concrete physical states of the computing system) are rarely identified and treated as items in practice – even though they may indeed be affirmed as items in theoretical discussions. On the other hand, objects that manifestly fail to meet the basic ontological criteria for FRBR items are commonly treated as if they are items. We describe this situation and, based on a re‐factoring of FRBR into a set of roles (relationships) rather than a set of entity types, explore two possible resolutions. One, favored by the second author, is consistent with the ontology implicit in the original FRBR vision, but allows assignment of item attributes and roles to things that are not items; the other, favored by the first author, is a radical departure from the underlying FRBR ontology, but preserves the original attribute assignments and roles.
Usability beyond the interface: Designing a portal for text analysis
Authors: Cherry Joan , Duff Wendy , Freund Luanne 
Published: February 2009

AbstractWe report on a two‐phase usability analysis of the Text Analysis Portal for Research (TAPoR). The first phase consisted of 20 contextual inquiry interviews and the second phase, a further 17 usability interviews with text analysis researchers. Findings suggest that the conceptual design of the portal needs to emphasize text content, functionality and text analysis tasks rather than text format and text analysis tasks, and that terminology was a major obstacle in use of the portal. Study results were used to guide the re‐design of the portal.
Patterns and outcomes of federal agency funding for libraries and information science
Authors: Hahn Trudi Bellardo 
Published: February 2009

AbstractBased on an extensive literature search as well as additional information gathered from federal agencies, including congressional budget requests, congressional testimony, issue summaries, news releases, and personal interviews with federal agency leaders, this poster addresses the patterns and influence of funding in the United States for research and development involving a broad range of topics subsumed under the diverse field of library and information science (LIS). These topics include traditional support for library development and operations, literacy programs in libraries, digitization and preservation of significant library collections of all kinds, disaster recovery, research on all aspects of information services, retrieval, use, and access, as well as developments in technologies for enhanced access to information in all forms and formats, and more. This broad perspective is necessary because the LIS field is fragmented, multi‐ and cross‐disciplinary, with little consensus about a central paradigm or research agenda.
Web 2.0: A new dynamic in information services for libraries
Authors: Randeree Ebrahim , Mon Lorri 
Published: February 2009

AbstractThe Internet is transforming users from information consumers into interactive information generators. The growth of Web 2.0 and social computing has been phenomenal. The web has extended beyond a search tool to become a mechanism for participatory content creation and dissemination. We investigate the extent of awareness of the phenomenon among undergraduate and graduate students, the usage of Web 2.0 and social computing sites, and the role of librarians under this new paradigm.
Bridging social and private interactions: Collaborative Information Retrieval in K‐12 learning contexts
Authors: Meyers Eric M. 
Published: February 2009

AbstractUntil recently, most models of information seeking and retrieval did not take into account other searchers or peers in the social/organizational environment (Wilson, 1999). Donald Case's (2007) survey of research on information seeking, needs and behavior further illustrates this omission: in the research literature, other persons are portrayed as sources of information, but not actively involved in the search process as collaborators. The concept of Collaborative Information Retrieval (CIR), on the other hand, identifies that peers and other human intermediaries play an important role in information behavior, both in formal and informal contexts. Researchers have documented the presence of collaboration in student information behavior in school libraries; however, the CIR concept has not been directly explored in K‐12 education. The study of CIR in K‐12 education may illustrate ways to improve the efficacy of our instructional programs in information literacy, as well as suggest requirements for the design of information systems and services.
Clinical and genetic analysis of lipid storage myopathies
Authors: Ohkuma Aya , Noguchi Satoru , Sugie Hideo , Malicdan May Christine V. , Fukuda Tokiko , Shimazu Kunio , López Luis Carlos , Hirano Michio , Hayashi Yukiko K. , Nonaka Ikuya , Nishino Ichizo 
Published: February 2009

AbstractCausative genes have been identified only in four types of lipid storage myopathies (LSMs): SLC22A5 for primary carnitine deficiency (PCD); ETFA, ETFB, and ETFDH for multiple acyl‐coenzyme A dehydrogenation deficiency (MADD); PNPLA2 for neutral lipid storage disease with myopathy (NLSDM); and ABHD5 for neutral lipid storage disease with ichthyosis. However, the frequency of these LSMs has not been determined. We found mutations in only 9 of 37 LSM patients (24%): 3 in SLC22A5; 4 in MADD‐associated genes; and 2 in PNPLA2. This low frequency suggests the existence of other causative genes. Muscle coenzyme Q10 levels were normal or only mildly reduced in two MADD patients, indicating that ETFDH mutations may not always be associated with CoQ10 deficiency. The 2 patients with PNPLA2 mutations had progressive, non‐episodic muscle disease with rimmed vacuoles. This suggests there is a different pathomechanism from other LSMs. Muscle Nerve 39: 333–342, 2009
Racial differences in myasthenia gravis in Alabama
Authors: Oh Shin J. , Morgan Marla B. , Lu Liang , Hatanaka Yuki , Hemmi Shoji , Young Angela , Claussen Gwendolyn C. 
Published: February 2009

AbstractDemographic, clinical, and laboratory features were compared in 235 white and African‐American (AA) patients with myasthenia gravis (MG) at the University of Alabama at Birmingham Neuromuscular Disease Clinic from May 2003 to January 2008. Seventy nine percent of patients were white. Acetylcholine receptor antibody was positive in 71% of white patients and in 59% of AA. In patients with seronegative generalized MG, the rate of positive muscle‐specific tyrosine kinase antibody (MuSK‐Ab) was significantly higher in AA than it was in whites (50% in AA vs. 17% in whites). Ocular MG was seronegative in 75% of AA patients. In AA, MG occurred earlier and more frequently in females, whereas, in whites, disease onset was later and more common in males. Another significant difference was a higher percentage of abnormality on repetitive nerve stimulation in AA. There was also a tendency for more severe forms of MG in AA. There are racial differences in MG between whites and AA in Alabama. These racial differences highlight the need to study biological factors in the pathogenesis of MG and to assess different approaches in diagnosis and treatment. Muscle Nerve, 2008
Homozygous contiguous gene deletion of 13q12 causing LGMD2C and ARSACS in the same patient
Authors: McMillan Hugh J. , Carter Melissa T. , Jacob Pierre J. , Laffan Eoghan E. , O'Connor Michael D. , Boycott Kym M. 
Published: February 2009

AbstractWe describe a 10‐year‐old girl with limb‐girdle muscular dystrophy type 2C (LGMD2C, gamma‐sarcoglycan deficiency) with additional features that include progressive lower limb spasticity, peripheral neuropathy, and ataxia. The gene for LGMD2C lies in close approximation to the gene for autosomal recessive spastic ataxia of Charlevoix–Saguenay (ARSACS) on chromosome 13q12. The clinical presentation was suspicious for a genomic rearrangement affecting the expression of both genes. Using chromosomal microarray analysis, a homozygous deletion that encompassed the genes for both disorders was identified. This is the first report of a patient with both neurological diseases, and this case illustrates the clinical utility of microarray technology in the investigation of patients with unusual presentations. Muscle Nerve 39: 396–400, 2009
Inhibition of myostatin with emphasis on follistatin as a therapy for muscle disease
Authors: Rodino‐Klapac Louise R. , Haidet Amanda M. , Kota Janaiah , Handy Chalonda , Kaspar Brian K. , Mendell Jerry R. 
Published: February 2009

AbstractIn most cases, pharmacologic strategies to treat genetic muscle disorders and certain acquired disorders, such as sporadic inclusion body myositis, have produced modest clinical benefits. In these conditions, inhibition of the myostatin pathway represents an alternative strategy to improve functional outcomes. Preclinical data that support this approach clearly demonstrate the potential for blocking the myostatin pathway. Follistatin has emerged as a powerful antagonist of myostatin that can increase muscle mass and strength. Follistatin was first isolated from the ovary and is known to suppress follicle‐stimulating hormone. This raises concerns for potential adverse effects on the hypothalamic–pituitary–gonadal axis and possible reproductive capabilities. In this review we demonstrate a strategy to bypass off‐target effects using an alternatively spliced cDNA of follistatin (FS344) delivered by adeno‐associated virus (AAV) to muscle. The transgene product is a peptide of 315 amino acids that is secreted from the muscle and circulates in the serum, thus avoiding cell‐surface binding sites. Using this approach our translational studies show increased muscle size and strength in species ranging from mice to monkeys. Adverse effects are avoided, and no organ system pathology or change in reproductive capabilities has been seen. These findings provide the impetus to move toward gene therapy clinical trials with delivery of AAV‐FS344 to increase size and function of muscle in patients with neuromuscular disease. Muscle Nerve 39: 283–296, 2009
Giant lymphadenopathy infiltrated by gaucher cells mimicking lymphoma
Authors: Yağci Begül , Salor Özge , Yalçin Bilgehan , Gürakan Figen , Güçer Şafak , Büyükpamukçu Münevver 
Published: February 2009

AbstractGaucher disease (GD) is a lysosomal storage disease characterized by deficiency of β‐glucocerebrosidase, which results in accumulation of glucocerebroside in reticuloendothelial system, bone marrow infiltration, progressive hepatosplenomegaly, and skeletal complications. Herein we report a 5‐year‐old female with GD receiving enzyme replacement therapy who had giant mesenteric lymphadenopathies. Pediatr Blood Cancer 2009;52:870–871. © 2009 Wiley‐Liss, Inc.
Oral ulceration: GP guide to diagnosis and treatment
Authors: Flint Stephen 
Published: February 2009

AbstractSimple mouth ulcers are usually self‐limiting and rarely present in general practice. However, severe, recurrent or persistent oral ulceration can be extremely painful and may result from an underlying systemic pathology. Dr Flint describes the different causes of oral ulcers and discusses treatment options. Copyright © 2006 Wiley Interface Ltd
Differentially constrained mobile robot motion planning in state lattices
Authors: Pivtoraiko Mihail , Knepper Ross A. , Kelly Alonzo 
Published: February 2009

AbstractWe present an approach to the problem of differentially constrained mobile robot motion planning in arbitrary cost fields. The approach is based on deterministic search in a specially discretized state space. We compute a set of elementary motions that connects each discrete state value to a set of its reachable neighbors via feasible motions. Thus, this set of motions induces a connected search graph. The motions are carefully designed to terminate at discrete states, whose dimensions include relevant state variables (e.g., position, heading, curvature, and velocity). The discrete states, and thus the motions, repeat at regular intervals, forming a lattice. We ensure that all paths in the graph encode feasible motions via the imposition of continuity constraints on state variables at graph vertices and compliance of the graph edges with a differential equation comprising the vehicle model. The resulting state lattice permits fast full configuration space cost evaluation and collision detection. Experimental results with research prototype rovers demonstrate that the planner allows us to exploit the entire envelope of vehicle maneuverability in rough terrain, while featuring real‐time performance. © 2009 Wiley Periodicals, Inc.
Experience with voltage control from large offshore windfarms: the Danish case
Authors: Akhmatov Vladislav 
Published: February 2009

AbstractThis paper gives an overview of the state of the art and lists future challenges to reactive power and voltage control in the Danish transmission system in relation to large offshore windfarms. Today, the reliable and stable operation of the Danish transmission system is based on the voltage and frequency control carried out at central, conventional power plants. Moreover, the control of some larger decentralized combined heat and power units is activated for voltage control and system balancing, which is specific for the Danish system. In the years to come, according to the government's goal of increasing the share of renewable energy sources in the Danish power system, the share of large offshore windfarms in the Danish power generation mix will increase greatly, replacing central power plants, including their control characteristics during periods of strong winds. Large offshore windfarms must therefore provide the transmission system with the necessary voltage and frequency control, e.g. ancillary services, and ensure secure operation of the power system through their contribution to system service. Danish experience, based on the operation of a system with two large offshore windfarms and several smaller ones, has shown that the efficient use of windfarms' reactive power and voltage control for the on‐land transmission system might be limited by several factors. Among such limiting factors are the reactive power and current capability limits of the electronic power converters and switchable capacitor banks of the offshore wind turbines, which are smaller than those of central power plants measured per unit of the active power rating. Combine this with the use of AC cables, tens of kilometres long, to connect the large offshore windfarms to the on‐land transmission system, the reactive power range available to the transmission system gets poor. The Transmission System Operator should already take such limiting factors and alternative solutions for efficient reactive power and voltage control, such as incorporation of a reactive power compensation unit at the on‐land point of connection or evaluation of a Voltage Sourced Converter‐High Voltage Direct Current instead of an AC connection, into consideration during the planning phase for a windfarm connection. Copyright © 2009 John Wiley & Sons, Ltd.
The Other Face of Bunsen's Cacodyl Disulfide, Me2As(S)‐S‐AsMe2: The Lewis‐Base Behaviour Towards Heavy Metal Cations
Authors: Ioannou Panayiotis V. , Vachliotis Dimitris G. , Sideris Theodore D. 
Published: February 2009

AbstractThe reaction of Bunsen's cacodyl disulfide, Me2As(S)‐S‐AsMe2, with heavy metal cations in methanol produces insoluble salts (complexes) of dimethyldithioarsinic acid, Me2AsS2H, and dimethyl arsenium ion, Me2As:+. This arsenium ion prefers to react with Me2As(S)‐S‐AsMe2, when in excess, compared to AcO− or MeOH/H2O and it is also reactive towards sulfur (Sx, x = 1‐8) producing the stabilized dimethylarsino sulfenium cation, $\rm Me_{2}As- {\mathop{\rm{S}}\limits^{.}_{\ddot{}}} ^{+} \longleftrightarrow Me_{2}\mathop{\rm{A}}\limits^{+}_{} s=\mathop{\rm{S}}\limits^{.}_{\ddot{}}$. The complexes (Me2AsS2)xM (x = 1 or 2) are unstable in the presence of their own heavy metal cations decomposing to colored solids. In an attempt to prepare salts of Me2AsSH, the reactions of (Me2AsS2)xM with triphenylphosphine and trimethyl phosphite gave the metal sulfide and Me2As‐S‐AsMe2 instead.
Solvent‐Induced Pseudopolymorphism of a New Dinuclear Oxovanadium(V) Compound Based on 2,6‐Di(hydroxymethyl)‐4‐methylphenol
Authors: Chen Lian , Jiang Feilong , Wu Mingyan , Li Ning , Xu Wentao , Yan Chunfeng , Hong Maochun 
Published: February 2009

AbstractReactions of VO2(acac) (Hacac = acetylacetone) and 2,6‐Di(hydroxymethyl)‐4‐methylphenol (H3L) in different organic solvents give rise to two pseudopolymorphs of a new dinuclear oxovanadium(V) compound, [Et3NH]2[V2O4(HL)2] (1) and [Et3NH]2[V2O4(HL)2]·H2O (2). The compounds have been synthesized and characterized by elemental analyses, IR spectra and single‐crystal X‐ray diffraction. X‐ray diffraction analyses reveal that 1 and 2 have different weak interactions and display remarkably distinct hydrogen‐bonded networks.
Structural and Raman Spectroscopic Investigations of K4BaSi3O9 and K4CaSi3O9
Authors: Arroyabe Erik , Kaindl Reinhard , Kahlenberg Volker 
Published: February 2009

AbstractThe crystal structures of K4BaSi3O9 and K4CaSi3O9 have been characterized by X‐ray diffraction techniques as well as Raman spectroscopy. The structure of K4CaSi3O9 has been refined from powder diffraction data via the Rietveld method using polycrystalline material prepared from solid state reactions. The compound is isostructural with form I of K4SrSi3O9. It crystallizes with 16 formula units in a cubic primitive cell (a = 15.94014(3) Å, V = 4050.20(1) Å3) and adopts space group $Pa{\bar 3}$. K4CaSi3O9 belongs to the group of cyclosilicates and contains highly puckered twelve‐membered [Si12O36]‐rings centered on the ${\bar 3}\rm -axes$. Five of the seven crystallographically independent alkaline and alkaline earth cations are surrounded by six oxygen ligands in the form of distorted octahedra, which share opposite triangular faces and form non‐intersecting columns parallel to the body diagonals of the cubic unit cell. This arrangement corresponds to one of the cubic cylinder or rod packings. The two remaining sites have more irregular coordination environments with eight next oxygen neighbors. High temperature X‐ray powder diffraction data have been collected to determine the thermal expansion of this material: between room temperature and 700 °C the coefficient of thermal expansion has a value of α = 12.9(2) × 10−6 [°C−1]. Single crystals of K4BaSi3O9 have been obtained from the devitrification of a glass with the same composition. The structure was determined from a single crystal diffraction data set collected at −100 °C and refined to a final R index of 0.0298 for 1288 observed reflections (I > 2σ(>I)). The compound is isostructural with modification II of K4SrSi3O9. Basic crystallographic data are as follows: space group Ama2, a = 11.0695(15) Å, b = 8.0708(10) Å, c = 11.905(2) Å, V = 1063.6(3) Å3, Z = 4. With respect to the silicate anions the material can be classified as a sechser single chain silicate. The crankshaft‐like chains run parallel to [100] and are linked by K and Ba cations, which are distributed among five crystallographically independent sites. The coordination polyhedra of two of the non‐tetrahedral cations can be described by distorted octahedra sharing opposite triangular faces. They build non‐intersecting columns parallel to [011] and [0‐11], respectively. The other sites exhibit more irregular coordination spheres with 7‐9 neighbours.