bluuebunny/crossref_metadata_2025_split huggingface dataset:
Seismic response analysis of cliff-attached isolated structures considering SSI effect under long-period ground motion in the far field
Authors: Yang Zhuoxin , Liu Dewen , Ling kangjie , Ban TAO , Zhao Yunlong , Sun Rui , Sun Weiwei 
Published: April 2024

Abstract

Cliff-attached constructions are buildings that are directly connected to and aligned with the vertical faces of mountains. The building is built with its backs on the cliff. Due to its complex grounding relationship, structural stress and deformation characteristics differ from conventional structures, so the SSI effect must be considered. Long periods, extended durations, and rich low-frequency components relative to ordinary ground vibration characterize long-period ground vibration in the far field. For a seismic isolation-type structure with a long period, it is especially complicated to consider the SSI (soil-structure interaction) effect, which needs to be explored in depth. On this basis, two structural configurations are established for analysis: the cliff-attached inter-story isolated structure and the double-story isolated structure. A comparison of these arrangements is conducted both with and without considering the impacts of soil-structure interaction. An examination of the extent of influence from regular earthquakes and far-field long-period earthquakes on the cliff isolation structure is performed under three-dimensional ground motion stimulation. The results suggest that the seismic reaction of cliff isolation structures to far-field long-period earthquakes exceeds that of conventional earthquakes. Particularly evident under three-dimensional ground motion conditions, notably during far-field harmonic-like seismic events, and the response is particularly significant. When factoring in the Soil-Structure Interaction (SSI) effect, it becomes apparent that the response of the cliff-attached structure is most pronounced when situated atop a soft soil foundation. As the soil stiffens, the damping efficacy of the double-story isolated structure decreases, though it continues to outperform the inter-story isolated structure. In addition, accounting for the SSI effect enhances the seismic response of cliff-attached isolation structures, especially in part connected to a mountain body that experiences obvious stress concentration and deformation, which should be thoroughly addressed during the structural design process. The improved stability of the double-story isolated structure's isolation bearings enables effective mitigation of tensile stress within the bearings, thus alleviating the problem of excessive tensile stress, and at the same time reducing the risk of the high-rise structure toppling under rare earthquakes.
Xanthohumol inhibits osteosarcoma proliferation, migration, and invasion via EFEMP1/PI3K/AKT axis
Authors: Wang Yun , Yan Lei , Li RuoQi , Lian Jing , Wu ZhuangZhuang , Sun XiaoJuan , Lv Zhi 
Published: April 2024

Abstract

Background
Osteosarcoma (OS) is a tumor of bone. Xanthohumol (XN) has been found to have antitumor effects. However, it is not known whether XN can prevent the development of OS.
Method
The malignant phenotypes of OS cell lines were evaluated using CCK-8, clone-formation, EdU, Transwell, and wound-healing assays. The molecular mechanism of XN action was investigated by transcriptome sequencing. mRNA levels in OS cells were examined by q-PCR and protein by western blotting and immunofluorescence, while Ki-67 and PCNA levels in tumors were assessed using immunohistochemistry.
Results
XN dose-dependently blocked proliferation, migration, and invasion in OS cell lines. Transcriptome sequencing revealed that EFEMP1 expression was significantly reduced after XN treatment, which was shown by rescue assays to have a tumor-suppressive effect. Reduced levels of EFEMP1/PI3K/AKT axis after XN treatment were demonstrated by western blotting.
Conclusion
XN blocks OS tumorigenic behavior by inhibition of the EFEMP1/PI3K/AKT axis.
Two Critiases and Atlantis From the history of Athenian oligarchic thought
Authors: Суриков И.Е. 
Published: April 2024

Вопрос о том, в чьи уста вложена Платоном в «Тимее» и «Критии» легенда об Атлантиде дискуссионен. Согласно традиционной точке зрения, рассказывающий ее Критий тождественен известному олигарху конца V в. до н.э. Критию, сыну Каллесхра (дяде Платона), в 404–403 гг. до н.э. возглавлявшему репрессивный режим «Тридцати тиранов» в Афинах. Однако такая идентификация Крития вышеупомянутых диалогов порождает непреодолимые хронологические трудности. В свое время по эпиграфическим данным стал известен другой Критий (сын Леаида), дед «тирана», и крайне велика вероятность того, что именно он выведен Платоном в ка-честве действующего лица «Тимея» и «Крития». Обоснованию этого тезиса посвящена эта часть статьи. В том случае, если он верен, перед нами предстает целая семья, в которой крайне-олигархические воззрения передавались по наследству. Данное положение хорошо согласуется с тем фактом, что еще один представитель этой семьи – Каллесхр (отец младшего Крития и сын старшего) – тоже был политиком-олигархом.
Debatable is the question as to into whose mouth the Atlantis legend of the Timaeusand Critias was put by Plato. According to the traditional opinion, Critias, who tells it, is identical with the noted late fifth-century B.C. oligarch Critias son of Callaeschrus (Plato’s uncle), who was at the head of the repressive “Thirty tyrants” regime in Athensin 404–403 B.C. However, such an identification of Critias gives rise to very serious and insurmountable chronological difficulties. Some time ago, another Critias (son of Leaides), the “tyrant”’ grandfather, became known from epigraphic data, and extremely likely is possibility that it is he who was depicted by Plato as a character of the Timaeus and Critias. This part of the article is devoted to the substantiation of this thesis. If it is correct, an entire family appears before us, in which extremely oligarchic position was hereditary. Such a situation is well agreed with the fact that another member of the family, Callaeschrus (father of the younger Critias and son of the elder one) was also an oligarchic politician.
The Fictional and Real History: Legitimation of Yi Seong-gye (Taejo, 1392-1398), the Founder of the Korean Kingdom of Joseon (1392-1897)
Authors: Чеснокова Н.А. 
Published: April 2024

В статье анализируется, как в корейских исторических источниках XV в. отражен приход к власти Ли Сонге (Тхэджо, 1392–1398) – основателя корейского государства Чосон (1392–1897). Цель исследования – выявить способы легитимации власти в средневековой Корее. Рассмотрены способы легитимации власти, которые предпринимались как самим Ли Сонге, так и его потомками позднее. Было выявлено, что легитимация власти Ли Сонге опиралась одновременно на конфуцианскую традицию, буддизм и собственные корейские представления об идеальном правителе.
The article focuses on the descriptions of Yi Seong-gye (Taejo, 1392-1398), the founder of the Korean Kingdom of Joseon (1392-1897),’s enthronement in various Korean source written in the 15th century by Korean intellectuals. The main goal of the study is to describe ways of legitimating royal power in medieval Korea. To achieve this task, I characterized the ways Yi Seong-gye and his later disciples used to prove his excellence. The conclusion of the study explains that Yi Seong-gye’s legitimacy was supported by Confucian tradition, Buddhist religion and rituals, and unique Korean ideas of a “great ruler”.
Austrian Federal Theatres as an Object of Cultural Policy, 1918-1945: Survival, Adaptation, Cultural Capital
Authors: Головлев А.И. 
Published: April 2024

В данной статье Австрийские Федеральные театры рассматриваются как крупнейшая организационная единица австрийской культурной политики с точки зрения её концептуализации, применения и анализа. Долголетие этого театрального конгломерата скорее объясняется зависимостью от траектории и доминирующими моделями мышления в бюрократии, культурной среде и обществе Австрии чем настоящей борьбой за экономическую эффективность. В первой половине XX в. Федеральные театры пережили две мировые войны, революцию, экономический кризис и установление двух диктатур. Значительный культурный капитал театров, консервативные тенденции в менеджменте, а также способность абсорбировать и нейтрализовать перемены в экономической и политической обстановке помогли театрам преодолеть повороты краткосрочной конъюнктуры. Культурный капитал устойчиво превалирует над экономическими и политическими обстоятельствами.
The Austrian Federal Theatres are investigated as the largest organizational unity within Austrian cultural politics from a viewpoint of its conceptualization, implementation, and analysis. The longevity of this theatre conglomerate is better explained by path dependence and predominant patterns of thinking within Austria’s bureaucracy, cultural milieu and society than as a genuine strife for economic efficiency. In the first half of the 20th century, the Federal Theatres survived two world wars, a revolution, an economic crisis, and the establishment of two dictatorships. Theatres’ significant cultural capital, conservative tendencies in management, and the ability to absorb and neutralize changes in economic and political conditions helped theatres to overcome the vicissitudes of short-term conjuncture. Cultural capital has consistently prevailed over economic and political circumstances.
Encapsulated polyphenols in functional food production
Authors: Bobrysheva Tatyana , Anisimov Georgy , Zolotoreva Marina , Evdokimov Ivan , Budkevich Roman , Muravyev Alexandr 
Published: April 2024

Polyphenols are present as nutrient components in many functional food formulations. However, their bioavailability is quite low, and they tend to degrade under extreme technological conditions, e.g., heating, pH, etc. Moreover, polyphenols are known for their specific bitter taste. As a result, a large amount of polyphenols spoils the sensory properties of the finished product. Encapsulation seems a prospective solution to this problem. This article provides a comprehensive review of scientific publications on various methods of polyphenol encapsulation.
The review covered publications registered in PubMed, Google Scholar, ResearchGate, Elsevier, eLIBRARY.RU, and Cyberleninka in 2002–2023 with a focus on original research articles published after 2012. The search involved such keywords as polyphenols, encapsulation, flavonoids, delivery systems, and functional products.
Encapsulating materials are made of organic or inorganic substances, as well as of their combinations. Mineral salts delay the contact between polyphenols and taste buds. However, they are not resistant enough to gastric juice. In this respect, organic matrices are more effective. Carbohydrates protect active molecules from degradation in the stomach. Liposomes increase the bioavailability of polyphenols. Milk or whey proteins also proved quite effective for a number of reasons. First, they mask the astringent taste, which makes it possible to include more polyphenols in functional food formulations. Second, the resulting product is fortified with valuable proteins and essential amino acids. Third, high concentrations of polyphenols possess enough antioxidant properties to increase the shelf-life.
Polyphenol encapsulation is an effective method of functional product design, especially in the sphere of foods made for dietary nutrition, sports, preventive diets, etc.
Microplastic inhibits the sorption of trichloroethylene on modified biochar
Authors: Lu Hainan 
Published: April 2024

ABSTRACT

Biochar (BC) was used to remove trichloroethylene (TCE) from soil and water phases, and BC modification changed the sorption behavior of pollutants. Microplastics are emerging pollutants in the soil and water phases. Whether microplastics can affect the sorption of TCE by modified BC is not clear. Thus, batch sorption kinetics and isotherm experiments were conducted to elucidate the sorption of TCE on BC, and BC combined with polyethylene (PE) or polystyrene (PS). The results showed that HCl and NaOH modification increased TCE sorption on BC, while HNO3 modification inhibited TCE sorption on BC. When PE/PS and BC coexisted, the TCE sorption capacity decreased significantly on BC-CK + PE, BC-HCl + PE, BC-HNO3 + PE, BC-NaOH + PE, and BC-NaOH + PS, which was likely due to the preferential sorption of PE/PS on BC samples. We concluded that microplastics can change TCE sorption behavior and inhibit TCE sorption on BC samples. Thus, the interaction of BC and microplastics should be considered when BC is used for TCE removal in soil and water remediation.
An improved method for isotopic and quantitative analysis of dissolved organic carbon in natural water samples
Authors: Li Yuhong , Wang Mingshi , Zhang Dong 
Published: April 2024

ABSTRACT

A wet chemical oxidation (WCO) method has been widely used to obtain the dissolved organic carbon (DOC) content and carbon isotope (δ13CDOC) ratios. However, it is sometimes difficult to get high precision results because not enough CO2 was oxidized from the natural water samples with low DOC concentrations. This improvement primarily aims to increase the water sample volume, improve the removal rate of dissolved inorganic carbon (DIC), and minimize the blank DOC from the standard solution. Following the improved procedure, the δ13C ratios of standardized DOC solutions were consistent with their actual values, and their differences were less than 0.2‰. The improved method demonstrated good accuracy and stability when applied to natural water samples with DOC concentrations ≥0.5 mg L−1, with the precisions of DOC concentrations and δ13C ratios were better than 0.07 mg L−1 and 0.1‰, respectively. More importantly, this method saved much pre-treatment time and realized batch processing of water samples to obtain their DOC contents and isotope ratios.
Pro- and Anti-inflammatory Biomarkers Responses after Aerobic Training
in Heart Transplant Recipients: A Systematic Review and Meta-analysis
Authors: Franzoni Leandro Tolfo , da Motta Stephanie Bastos , Carvalho Gabriel , Costa Rochelle Rocha , Ahner Mabel Marciela , Saffi Marco Aurélio Lumertz , Pereira Alexandre Araújo , Pereira Adamastor Humberto , da Silveira Anderson Donelli , Stein Ricardo 
Published: April 2024

Background:
Physical exercise (PE) may improve plasma concentration of interleukin-
6 (IL-6), tumor necrosis factor-alpha (TNF-alpha), and adiponectin (adpN) in heart transplant
(HT) patients. However, no consistent data is available on this population.

Aim:
Thus, we aimed to conduct a systematic review and meta-analysis on the effects of PE
over these pro- and anti-inflammatory biomarkers in HT patients.

Methods:
Following the guidelines established by the Preferred Reporting Items for Systematic
Reviews and Meta-Analyses (PRISMA) 2020 statement, we conducted a systematic literature
search in the PubMed, Cochrane, and Scopus databases. Outcomes included IL-6, TNF-alpha,
and adpN. Effect size (ES) was calculated using the standardized mean difference with a 95%
confidence interval (CI).

Results:
The PE group (aerobic modality) was associated with reduced IL-6 compared to the
control group (ES: −0.53; 95% CI: −0.99 to −0.06 pg/mL; P = 0.026). However, the PE group
did not show a significant effect on TNF-alpha and adpN levels (ES: −0.33; 95% CI: −0.79 to
0.13; P = 0.16 and ES: −0.20; 95% CI: −0.70 to 0.30 pg/mL; P = 0.444, respectively).

Conclusion:
PE is associated with IL-6 reductions, although TNF alpha and adpN did not
change after this intervention in HT patients. Therefore, PE is an effective intervention to downregulate
IL-6 in post-HT patients.
Exploring the Implementation of Shared Decision-Making Involving Health Coaches for Diabetes and Hypertension Self-Management: Qualitative Study
Authors: Yoon Sungwon , Tan Chao Min , Phang Jie Kie , Liu Venice Xi , Tan Wee Boon , Kwan Yu Heng , Low Lian Leng 
Published: April 2024

Background
An emerging focus on person-centered care has prompted the need to understand how shared decision-making (SDM) and health coaching could support self-management of diabetes and hypertension.

Objective
This study aims to explore preferences for the scope of involvement of health coaches and health care professionals (HCPs) in SDM and the factors that may influence optimal implementation of SDM from the perspectives of patients and HCPs.

Methods
We conducted focus group discussions with 39 patients with diabetes and hypertension and 45 HCPs involved in their care. The main topics discussed included the roles of health coaches and HCPs in self-management, views toward health coaching and SDM, and factors that should be considered for optimal implementation of SDM that involves health coaches. All focus group discussions were audio recorded, transcribed verbatim, and analyzed using thematic analysis.

Results
Participants agreed that the main responsibility of HCPs should be identifying the patient’s stage of change and medication education, while health coaches should focus on lifestyle education, monitoring, and motivational conversation. The health coach was seen to be more effective in engaging patients in lifestyle education and designing goal management plans as health coaches have more time available to spend with patients. The importance of a health coach’s personal attributes (eg, sufficient knowledge of both medical and psychosocial management of disease conditions) and credentials (eg, openness, patience, and empathy) was commonly emphasized. Participants viewed that addressing the following five elements would be necessary for the optimal implementation of SDM: (1) target population (newly diagnosed and less stable patients), (2) commitment of all stakeholders (discrepancy on targeted times and modality), (3) continuity of care (familiar faces), (4) philosophy of care (person-centered communication), and (5) faces of legitimacy (physician as the ultimate authority).

Conclusions
The findings shed light on the appropriate roles of health coaches vis-à-vis HCPs in SDM as perceived by patients and HCPs. Findings from this study also contribute to the understanding of SDM on self-management strategies for patients with diabetes and hypertension and highlight potential opportunities for integrating health coaches into the routine care process.
Using Smartphones to Enhance Vision Screening in Rural Areas: Pilot Study
Authors: Wang Zheng , Kempen John , Luo Gang 
Published: April 2024

Background
While it is treatable, uncorrected refractive error is the number one cause of visual impairment worldwide. This eye condition alone, or together with ocular misalignment, can also cause amblyopia, which is also treatable if detected early but still occurs in about 4% of the population. Mass vision screening is the first and most critical step to address these issues, but due to limited resources, vision screening in many rural areas remains a major challenge.

Objective
We aimed to pilot-test the feasibility of using smartphone apps to enhance vision screening in areas where access to eye care is limited.

Methods
A vision screening program was piggybacked on a charity summer camp program in a rural county in Sichuan, China. A total of 73 fourth and fifth graders were tested for visual acuity using a standard eye chart and were then tested for refractive error and heterophoria using 2 smartphone apps (a refraction app and a strabismus app, respectively) by nonprofessional personnel.

Results
A total of 5 of 73 (6.8%, 95% CI 2.3%-15.3%) students were found to have visual acuity worse than 20/20 (logarithm of minimal angle of resolution [logMAR] 0) in at least one eye. Among the 5 students, 3 primarily had refractive error according to the refraction app. The other 2 students had manifest strabismus (one with 72–prism diopter [PD] esotropia and one with 33-PD exotropia) according to the strabismus app. Students without manifest strabismus were also measured for phoria using the strabismus app in cover/uncover mode. The median phoria was 0.0-PD (IQR 2.9-PD esophoria to 2.2-PD exophoria).

Conclusions
The results from this vision screening study are consistent with findings from other population-based vision screening studies in which conventional tools were used by ophthalmic professionals. The smartphone apps are promising and have the potential to be used in mass vision screenings for identifying risk factors for amblyopia and for myopia control. The smartphone apps may have significant implications for the future of low-cost vision care, particularly in resource-constrained and geographically remote areas.
Myringoplasty – A Rewiev of 438 Cases
Authors: Filipche Ilija St. , Chakar Marina , Javari Sijavash 
Published: April 2024

Abstract
The medical records of 438 patients who underwent myringoplasty followed up for a minimum of one year in the period of 1980 and 2015 were revised. Examination under otomicroscope was done of the ear to be operated. This was carried out with a speculum under the operating microscope to be reliably asses the tympanic membrane, site of perforation, to rule out any other pathology and assess the status of ossicular chain. All the patients submitted primary myringoplasty surgery were operated under postauricular, endaural and transcanal approach with overlay, underlay and inlay methods. In the study the patients were divided into three groups depending upon the technique utilized to repair the tympanic membrane. When we compared overlay technique group with underlay technique group, it was observed that overlay technique was no statistically significant difference between these three groups in term of age wise distribution, gender wise distribution, duration of disease and cause of disease, due to matching at the time of selection. In this study the outcome in terms of graft uptake rate was slight better in the overlay technique (94%) as compared to the underlay technique (86.2%), though the difference was statistically insignificant, P>0.05. Patients selection may have had a role in the high success rate in the present study as patients presenting with middle ear pathology were excluded. The complications rate in the present study was quite low, no case in inlay group, three cases of graft lateralization in underlay group, and 19 cases in overlay group. In this study, better results were achieved with overlay technique may probably be due to less surgical manipulation and faster healing process.