bluuebunny/crossref_metadata_2025_split huggingface dataset:
Unusual Acylation Reaction of 1′‐Alkyl‐1′,4′‐dihydro‐2,3′‐biquinolines.
Authors: Kovalev D. A. , Antonova O. A. , Demidova N. V. , Aksenov A. V. 
Published: October 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Design, Synthesis and Biological Evaluation of Novel Tricyclic HIV‐1 Integrase Inhibitors by Modification of Its Pyridine Ring.
Authors: Metobo Sammy E. , Jin Haolun , Tsiang Manuel , Kim Choung U. 
Published: October 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Novel Pyridazine‐Fused Heterocyclic System: A New Route for the Synthesis of 2‐Alkyl/Aryl[1,3,4]thiadiazole[2′,3′:2,3]imidazo [4,5‐d]pyridazin‐8(7H)‐one.
Authors: Kolavi Gundurao , Hegde Vinayak , Khazi Imtiyaz Ahmed 
Published: October 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
A Very Short and Efficient Palladium‐Catalyzed Access to the 3,4‐Dihydro‐2H‐1,4‐benzoxazine Structure.
Authors: Dominczak Norbert , Lhoste Paul , Kryczka Boguslaw , Sinou Denis 
Published: October 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Exchange Reactions of 1,3‐Bis(nitroarylthio)propanes with Propane‐1,3‐dithiols.
Authors: Miroshnichenko A. V. , Demchuk D. V. , Nikishin G. I. 
Published: October 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Synthesis and Extraction Properties of Oxathiacrown Compounds Containing Benzyl Groups.
Authors: Rezekina N. A. , Rakhmanov E. V. , Lukovskaya E. V. , Bobylyova A. A. , Abramov A. A. , Chertkov V. A. , Khoroshutin A. V. , Anisimov A. V. 
Published: October 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Rhodium‐Catalyzed Synthesis of 1‐Alkynylphosphine Oxides from 1‐Alkynes and Tetraphenylbiphosphine.
Authors: Arisawa Mieko , Onoda Masato , Hori Chieko , Yamaguchi Masahiko 
Published: October 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Novel Organic Dyes for Efficient Dye‐Sensitized Solar Cells.
Authors: Li Shao‐Lu , Jiang Ke‐Jian , Shao Ke‐Feng , Yang Lian‐Ming 
Published: October 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Three Novel Terpenoids from Schisandra pubescens var. pubinervis
Authors: Huang Sheng‐Xiong , Yang Jing , Xiao Wei‐Lie , Zhu Yan‐Ling , Li Rong‐Tao , Li Li‐Mei , Pu Jian‐Xin , Li Xian , Li Sheng‐Hong , Sun Han‐Dong 
Published: October 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
A Tryptophan‐Containing Fluoroionophore Sensor with High Sensitivity to and Selectivity for Lead Ion in Water.
Authors: Ma Li‐Jun , Liu Yi‐Fu , Wu Yuqing 
Published: October 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Stereoselective Conversion of Anhydrovinblastine into Vinblastine Utilizing an Antivinblastine Monoclonal Antibody as a Chiral Mould.
Authors: Shirahama Tatsuya , Kohno Takeyuki , Kaijima Tomohiro , Nagaoka Yasuo , Morimoto Daisuke , Hirata Kazumasa , Uesato Shinichi 
Published: October 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Studies on Oxidative Transformations of Dinucleoside H‐Phosphonoselenoates.
Authors: Bollmark Martin , Kullberg Martin , Stawinski Jacek 
Published: October 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Biocatalytic Synthesis of a Nanostructured and Crystalline Bimetallic Perovskite‐Like Barium Oxofluorotitanate at Low Temperature.
Authors: Brutchey Richard L. , Yoo Edward S. , Morse Daniel E. 
Published: October 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Tailoring the Morphology and Assembly of Silver Nanoparticles Formed in DMF
Authors: Pastoriza‐Santos Isabel , Liz‐Marzan Luis M. 
Published: October 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Electrocyclic Ring‐Opening Reactions of gem‐Dibromocyclopropanes in the Synthesis of Natural Product and Related Compounds.
Authors: Halton Brian , Harvey Joanne 
Published: October 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Ring‐Closure Reactions of ortho‐Vinyl‐tert‐anilines and (Di)Aza‐Heterocyclic Analogues via the tert‐Amino Effect: Recent Developments
Authors: Matyus Peter , Elias Oliver , Tapolcsanyi Pal , Polonka‐Balint Agnes , Halasz‐Dajka Beata 
Published: October 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Polymers of Intrinsic Microporosity (PIMs): Organic Materials for Membrane Separations, Heterogeneous Catalysis and Hydrogen Storage
Authors: McKeown Neil B. , Budd Peter M. 
Published: October 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Separations and Syntheses of Chiral Compounds and Application to the Synthesis of Natural Products Using Fluorous Chemistry
Authors: Nakamura Yutaka , Takeuchi Seiji 
Published: October 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Hydrophobic and Hydrophilic Yoctowells
Authors: Wang Tianyu , Bhosale Sheshanath , Bhosale Sidhanath , Li Guangtao , Fuhrhop Juergen‐Hinrich 
Published: October 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Improved Catalyst for the Removal of Carbobenzyloxy Protective Groups
Authors: Humphries Kimberly B. , Mobus Konrad , Dunn Tracy D. , Chen Baoshu 
Published: October 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Theoretical Analysis of the Terahertz Spectrum of the High Explosive PETN
Authors: Allis Damian G. , Korter Timothy M. 
Published: October 2006

AbstractThe experimental solid‐state terahertz (THz) spectrum (3 to 120 cm−1) of the high explosive pentaerythritol tetranitrate (PETN, C5H6N4O12) has been modeled using solid‐state density functional theory (DFT) calculations. Solid‐state DFT, employing the BP density functional, is in best qualitative agreement with the features in the previously reported THz spectrum. The crystal environment of PETN includes numerous intermolecular hydrogen‐bonding interactions that contribute to large (up to 80 cm−1) calculated shifts in molecular normal‐mode positions in the solid state. Comparison of the isolated‐molecule and solid‐state normal‐mode calculations for a series of density functionals reveals the extent to which the inclusion of crystal‐packing interactions and the relative motions between molecules are required for correctly reproducing the vibrational structure of solid‐state THz spectra. The THz structure below 120 cm−1 is a combination of both intermolecular (relative rotations and translations) and intramolecular (torsions, large amplitude motions) vibrational motions. Vibrational‐mode analyses indicate that the first major feature (67.2 cm−1) in the PETN THz spectrum contains all of the optical rotational and translational cell modes and no internal (molecular) vibrational modes.
Aerosol‐Assisted CVD of Antimony Sulfide from Antimony Dithiocarbamates
Authors: Rodriguez‐Castro J. , Mahon M. F. , Molloy K. C. 
Published: October 2006

AbstractAsymmetric antimony dithiocarbamates, Sb[S2CN(Me)R]3 (R = Bu, Hex, Bz), can be thermally decomposed under a dynamic vacuum to yield high‐purity Sb2S3 rods. These precursors do not, however, have sufficient volatility for low‐pressure (LP) CVD, but are soluble in organic solvents and can be exploited in aerosol‐assisted (AA) CVD. Sb2S3 can be deposited using the latter procedure, but the film purity is dependent on substrate temperature. As temperature increases the films become more susceptible to oxidation, and the deposition of oxides and mixed oxide/sulfides becomes more prevalent.
Nachweis der Feuerwiderstandsdauer von Mauerwerk im Brandfall bei einer Kaltbemessung nach DIN 1053‐100:2006‐08. Anpassung der Aussagen in DIN 4102:1994‐03 einschließlich DIN 4102‐4/A1:2004‐11
Authors: Graubner Carl‐Alexander , Hahn Christine , Jäger Wolfram 
Published: October 2006

AbstractMit der Umstellung auf das neue Teilsicherheitskonzept nach DIN 1053‐100 tritt die Frage auf, wie der Nachweis der Feuerwiderstandsdauer von Mauerwerksbauteilen unter Brandbelastung zu führen ist. Um eine einfache und praktikable Lösung in der Schreibweise des neuen Sicherheitskonzeptes anbieten zu können, erfolgte eine Überführung des Ausnutzungsfaktors α2, jedoch mit den bisher angesetzten Lasten im Brandversuch entsprechend DIN 1053‐1. Der Beitrag stellt das Ergebnis in kurzer Form dar und gibt Erläuterungen dazu.
Selective Analysis of Secondary Amines Using Liquid Chromatography with Electrochemical Detection (LC‐EC)
Authors: Williams Celia K. , Koppang Miles D. 
Published: October 2006

AbstractIn a mixture of primary and secondary aliphatic amines, the primary amines were derivatized (masked) with o‐phthalaldehyde (OPA) followed by derivatization of the remaining secondary amines with ferrocenecarboxylic acid chloride (FAC). The “tagged” amines were analyzed by LC‐EC (liquid chromatography with electrochemical detection) using in‐series dual electrode detection. Chemically‐reversible oxidation of the FAC tagged secondary amines and their subsequent complementary oxidation and reduction signals coupled with chemically‐irreversible oxidation of OPA tagged primary amines provided the selectivity for quantitative secondary amine analysis. The procedure was also applied for the selective identification of fragment 4–11 (N‐terminus‐proline) of Substance P in the presence of other Substance P fragments with primary amino acids as their N‐termini.
An Amperometric Hydrogen Peroxide Biosensor Based on a Hemoglobin‐Immobilized Dopamine‐Oxidation Polymer/Prussian Blue/Au Electrode
Authors: Li Mingrui , Deng Chunyan , Chen Chao , Peng Limei , Ning Guohong , Xie Qingji , Yao Shouzhuo 
Published: October 2006

AbstractA novel method to immobilize hemoglobin (Hb) in a polymer grown from dopamine (DA) oxidation was proposed. The growth of the polymeric films during DA oxidation at the Prussian blue (PB) modified Au electrode in weak alkaline phosphate buffer (pH 9.18) and the immobilization of Hb into the polymeric films during their growth were traced by the electrochemical quartz crystal impedance analysis (EQCIA) method. A hydrogen peroxide (H2O2) biosensor was thus constructed, and effects of experimental parameters on the sensor performance, including the applied potential, solution pH and electroactive interferents, were examined. At an optimal potential of −0.25 V vs. SCE, the current response of the biosensor in the selected phosphate buffer (pH 5.29) was linear with the concentration of H2O2 from 0.01 to 4.5 mM, with a lower limit of detection of 0.5 μM (S/N=3), short response time (within 10 s) and good anti‐interferent ability. The Michaelis constant (Kmapp) was estimated to be 3.80 mM. Compared with the separate film of PB or Hb, the composite film of Hb and PB exhibited a higher catalytic activity toward the reduction of H2O2, as a result of the additive effect of the chemical and biological catalyses.
Numerical simulation of flapping‐wing insect hovering flight at unsteady flow
Authors: Zuo Decan , Peng Songlin , Chen Wenyuan , Zhang Weiping 
Published: October 2006

AbstractA computational fluid dynamics (CFD) analysis was conducted to study the unsteady aerodynamics of a virtual flying bumblebee during hovering flight. The integrated geometry of bumblebee was established to define the shape of a three‐dimensional virtual bumblebee model with beating its wings, accurately mimicking the three‐dimensional movements of wings during hovering flight. The kinematics data of wings documented from the measurement to the bumblebee in normal hovering flight aided by the high‐speed video. The Navier–Stokes equations are solved numerically. The solution provides the flow and pressure fields, from which the aerodynamic forces and vorticity wake structure are obtained. Insights into the unsteady aerodynamic force generation process are gained from the force and flow‐structure information. The CFD analysis has established an overall understanding of the viscous and unsteady flow around the virtual flying bumblebee and of the time course of instantaneous force production, which reveals that hovering flight is dominated by the unsteady aerodynamics of both the instantaneous dynamics and also the past history of the wing. A coherent leading‐edge vortex with axial flow and the attached wingtip vortex and trailing edge vortex were detected. The leading edge vortex, wing tip vortex and trailing edge vortex, which caused by the pressure difference between the upper and the lower surface of wings. The axial flow, which include the spanwise flow and chordwise flow, is derived from the spanwise pressure gradient and chordwise pressure gradient, will stabilize the vortex and gives it a characteristic spiral conical shape. Copyright © 2006 John Wiley & Sons, Ltd.
Stage‐specific alterations of the genome, transcriptome, and proteome during colorectal carcinogenesis
Authors: Habermann Jens K. , Paulsen Ulrike , Roblick Uwe J. , Upender Madhvi B. , McShane Lisa M. , Korn Edward L. , Wangsa Danny , Krüger Stefan , Duchrow Michael , Bruch Hans‐Peter , Auer Gert , Ried Thomas 
Published: October 2006

AbstractTo identify sequential alterations of the genome, transcriptome, and proteome during colorectal cancer progression, we have analyzed tissue samples from 36 patients, including the complete mucosa‐adenoma‐carcinoma sequence from 8 patients. Comparative genomic hybridization (CGH) revealed patterns of stage specific, recurrent genomic imbalances. Gene expression analysis on 9K cDNA arrays identified 58 genes differentially expressed between normal mucosa and adenoma, 116 genes between adenoma and carcinoma, and 158 genes between primary carcinoma and liver metastasis (P < 0.001). Parallel analysis of our samples by CGH and expression profiling revealed a direct correlation of chromosomal copy number changes with chromosome‐specific average gene expression levels. Protein expression was analyzed by two‐dimensional gel electrophoresis and subsequent mass spectrometry. Although there was no direct match of differentially expressed proteins and genes, the majority of them belonged to identical pathways or networks. In conclusion, increasing genomic instability and a recurrent pattern of chromosomal imbalances as well as specific gene and protein expression changes correlate with distinct stages of colorectal cancer progression. Chromosomal aneuploidies directly affect average resident gene expression levels, thereby contributing to a massive deregulation of the cellular transcriptome. The identification of novel genes and proteins might deliver molecular targets for diagnostic and therapeutic interventions. © Wiley‐Liss, Inc.
A FISH comparison of variant derivatives of the recurrent dic(17;20) of myelodysplastic syndromes and acute myeloid leukemia: Obligatory retention of genes on 17p and 20q may explain the formation of dicentric chromosomes
Authors: MacKinnon Ruth N. , Patsouris Cris , Chudoba Ilse , Campbell Lynda J. 
Published: October 2006

AbstractThe dic(17;20) is a recurrent unbalanced translocation occurring rarely in myelodysplastic syndromes and acute myeloid leukemia. We have studied eleven cases with the dic(17;20) or a more complex derivative, all of which showed deletion of 17p and 20q material. The tumor suppressor gene TP53 was not always lost, supporting a more distal gene as the target of these 17p deletions. All derivatives could be interpreted as having initially been formed as a dicentric chromosome, those with a larger amount of material between the centromeres having undergone further rearrangement to stabilize the chromosome while retaining proximal 17p and proximal 20q material. We propose that critical sequences on both 17p and 20q proximal to the sites of deletion must be retained during the critical 17p and 20q deletions. This would explain the excess of dicentric chromosomes resulting from 17;20 translocation, and the apparent stabilization of the unstable derivatives by further rearrangements which preserve 17p and 20q material. © 2006 Wiley‐Liss, Inc.
Gene expression in 16q is associated with survival and differs between Sørlie breast cancer subtypes
Authors: Wennmalm Kristian , Calza Stefano , Ploner Alexander , Hall Per , Bjöhle Judith , Klaar Sigrid , Smeds Johanna , Pawitan Yudi , Bergh Jonas 
Published: October 2006

AbstractWe have investigated the relationship between gene expression and chromosomal positions in 402 breast cancer patients. Using an overrepresentation approach based on Fisher's exact test, we identified disproportionate contributions of specific chromosomal positions to genes associated with survival. Our major finding is that the gene expression in the long arm of chromosome 16 stands out in its relationship to survival. This arm contributes 36 (18%) and 55 (11%) genes to lists negatively associated with recurrence‐free survival (set to sizes 200 and 500). This is a highly disproportionate contribution from the 313 (2%) genes in this arm represented on the used Affymetrix U133A and B microarray platforms (Bonferroni corrected Fisher test: P < 2.2 × 10−16). We also demonstrate differential expression in 16q across tumor subtypes, which suggests that the ERBB2, basal, and luminal B tumors progress along a high grade–poor prognosis path, while luminal A and normal‐like tumors progress along a low grade–good prognosis path, in accordance with a previously proposed model of tumor progression. We conclude that important biological information can be extracted from gene expression data in breast cancer by studying non‐random connections between chromosomal positions and gene expression. This article contains Supplementary Material available at http://www.interscience.wiley.com/jpages/1045‐2257/suppmat. © 2006 Wiley‐Liss, Inc.
A preliminary metabolomic analysis of older adults with and without depression
Authors: Paige Lisa A. , Mitchell Matthew W. , Krishnan K. Ranga R. , Kaddurah‐Daouk Rima , Steffens David C. 
Published: October 2006

AbstractBackgroundMetabolomics, the global science of biochemistry, is an emerging field that enables detection and quantification of small molecules involved in metabolic and signaling pathways. Metabolic signatures for disease and its treatment could provide valuable biomarkers and insights about disease mechanisms. In this pilot study, we evaluate the potential of metabolomics in the study of older depressed patients.MethodsWe performed a metabolomic analysis of blood plasma from nine depressed, 11 remitted, and ten never‐depressed older adults. Approximately 800 metabolites were analyzed, with comparisons made among the three groups.ResultsMetabolites that were altered in currently depressed patients when compared with controls included several fatty acids, glycerol and gamma‐aminobutyric acid (GABA). Analyses comparing concentrations in remitted and currently depressed patients revealed a pattern of metabolite alterations similar to the control vs currently depressed analyses. One difference observed in the remitted patients relative to the depressed patients was elevation of the concentration of the ketone 3‐hydroxybutanoic acid.ConclusionThese observations suggest that the depressed state may be associated with alterations in the metabolism of lipids and neurotransmitters, and that treatment with antidepressants adjusts some of the aberrant pathways in disease so that the patients in remission have a metabolic profile more similar to controls than to the depressed population. These results will need to be examined and validated in larger longitudinal cohorts. Copyright © 2006 John Wiley & Sons, Ltd.
Prophylactic transdermal treatment with physostigmine and scopolamine against soman intoxication in guinea‐pigs
Authors: Meshulam Yacov , Davidovici Rachel , Wengier Ada , Levy Aharon 
Published: October 2006

AbstractThis study was designed to evaluate the prophylactic efficacy of transdermally administered physostigmine (PHY) against soman exposure using guinea‐pigs. Transdermal PHY pad (3 cm2 kg−1; 60 μg cm−2), containing a vehicle based on propionic acid, was applied onto the dorsal back of the animals, 24 h before exposure to the organophosphate. At the time of exposure, PHY concentrations in brain and plasma were ca. 3.6 ng g−1 and 4.1 ng ml−1, respectively. Brain and whole blood cholinesterase (ChE) activity was inhibited to 70% and 47% of the original activity, respectively. Transdermal PHY by itself protected up to 70% of the animals exposed to 1.5 LD50 of soman (100% mortality was recorded in the control group). Combining transdermal PHY with Scopoderm provided full protection against 1.5 LD50 of soman (protection of 70% against 3 LD50). When the prophylactic treatment was combined with post‐exposure therapy (atropine, 10 mg kg−1; toxogonin, 10 mg kg−1) 1 min after 5 LD50 of soman, protection of 90% of the animals was achieved.