bluuebunny/crossref_metadata_2025_split huggingface dataset:
Synthesis and Biological Activity of 5′,9‐Anhydro‐3‐purine‐isonucleosides as Potential anti‐Hepatitis C Virus Agents.
Authors: Chun Byoung‐Kwon , Wang Peiyuan , Hassan Abdalla , Du Jinfa , Tharnish Phillip M. , Murakami Eisuke , Stuyver Lieven , Otto Michael J. , Schinazi Raymond F. , Watanabe Kyoichi A. 
Published: May 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Two New Dioxopiperazine Derivatives, Arestrictins A and B, Isolated from Aspergillus restrictus and Aspergillus penicilloides.
Authors: Itabashi Takeshi , Matsuishi Natsuna , Hosoe Tomoo , Toyazaki Norihiro , Udagawa Shun‐ichi , Imai Toshimichi , Adachi Mitsuru , Kawai Ken‐ichi 
Published: May 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Total Synthesis of (‐)‐Blepharocalyxin D.
Authors: Ko Haye Min , Lee Dong Gil , Kim Min Ah , Kim Hak Joong , Park Jaejoon , Lah Myoung Soo , Lee Eun 
Published: May 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Ascospiroketals A (I) and B (II), Unprecedented Cycloethers from the Marine‐Derived Fungus Ascochyta salicorniae.
Authors: Seibert Simon F. , Krick Anja , Eguereva Ekaterina , Kehraus Stefan , Koenig Gabriele M. 
Published: May 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
The Organocatalytic Direct Self‐Trimerization of Acrolein: Application to the Total Synthesis of Montiporyne F (III).
Authors: Hong Bor‐Cherng , Nimje Roshan Y. , Yang Chun‐Yao 
Published: May 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Enantioselective Synthesis of Oasomycin A (I). Part 1. Synthesis of the C1—C12 and C13—C28 Subunits.
Authors: Evans David A. , Nagorny Pavel , McRae Kenneth J. , Reynolds Dominic J. , Sonntag Louis‐Sebastian , Vounatsos Filisaty , Xu Risheng 
Published: May 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Total Synthesis of Rapamycin.
Authors: Maddess Matthew L. , Tackett Miles N. , Watanabe Hidenori , Brennan Paul E. , Spilling Christopher D. , Scott James S. , Osborn David P. , Ley Steven V. 
Published: May 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Total Synthesis of Herbimycin A.
Authors: Canova Sophie , Bellosta Veronique , Bigot Antony , Mailliet Patrick , Mignani Serge , Cossy Janine 
Published: May 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Bidirectional, Organocatalytic Synthesis of Lepidopteran Sex Pheromones.
Authors: de Figueiredo Renata Marcia , Berner Raphael , Julis Jennifer , Liu Ting , Tuerp David , Christmann Mathias 
Published: May 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Fungal Citridone D Having a Novel Phenylfuropyridine Skeleton.
Authors: Fukuda Takashi , Sakabe Yasunari , Tomoda Hiroshi , Omura Satoshi 
Published: May 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
A New Citryl Glycoside (I) from Gastrodia elata and Its Inhibitory Activity on GABA Transaminase.
Authors: Choi Jung‐Hyun , Lee Dong‐Ung 
Published: May 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Total Synthesis of Potential Antitumor Agent, (‐)‐Dictyostatin.
Authors: Ramachandran P. Veeraraghavan , Srivastava Amit , Hazra Debasis 
Published: May 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
The First Naturally Occurring Aromatic Isothiocyanates, Rapalexins A and B, Are Cruciferous Phytoalexins.
Authors: Pedras M. Soledade C. , Zheng Qing‐An , Gadagi Ravi S. 
Published: May 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Synthesis and Liquid Crystalline Properties of 3‐Substituted Pentane‐2,4‐dione, Pyrazole and Isoxazole Derivatives.
Authors: Han Jie , Guo Hui , Wang Xiao‐Guang , Pang Mei‐Li , Meng Ji‐Ben 
Published: May 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Synthesis and Antitumor Activity Evaluation of Some Schiff Bases Derived from 2‐Aminothiazole Derivatives.
Authors: Zhou Xin , Shao Ling , Jin Zhong , Liu Jian‐Bing , Dai Hong , Fang Jian‐Xin 
Published: May 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Compton Scattering Studies of 4f Ferromagnetism
Authors: Cooper M. J. , Duffy J. A. , Banfield Z. F. , Bebb A. M. , Blaauw L. , Shenton‐Taylor C. , Steer C. , Taylor J. W. 
Published: May 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
1‐Nitrogen‐Functionalized 2‐Phosphorus‐Functionalized Acetylenes and Bis(phosphorus‐functionalized)acetylenes
Authors: Witulski B. , Alayrac C. 
Published: May 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Optimized Hydrothermal Synthesis of Multi‐dimensional Hybrid Coordination Polymers Containing Flexible Organic Ligands
Authors: Paz Filipe A. Almeida , Rocha Joao , Klinowski Jacek , Trindade Tito , Shi Fa‐Nian , Mafra Luis 
Published: May 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Self‐Assembling Peptide Gels
Authors: Aggeli A. , Boden N. , Carrick L. M. , Mcleish T. C. B. , Nyrkova I. A. , Semenov A. N. 
Published: May 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
ansa‐Metallocene and Half‐Sandwich Complexes of Group‐3 Metals and Lanthanides Incorporating Fluorenyl‐Based Ligands: From Synthesis to Catalytic Applications
Authors: Kirillov Evgueni , Dash Aswini K. , Rodrigues Anne‐Sophie , Carpentier Jean‐Francois 
Published: May 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Use of Polyfunctionalized Pyridazines as Reactive Species for Building Chemical Diversity
Authors: Bourguignon J. J. , Oumouch S. , Schmitt M. 
Published: May 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Non‐Crosslinked Polystyrene‐Bound Reagents, Catalysts and Syntheses
Authors: Chen Jianian , Yang Guichun , Zhang Haiqing , Chen Zuxing 
Published: May 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Towards New Methodologies for the Synthesis of Biologically Interesting 6‐Substituted Pyrimidines and 4(3H)‐Pyrimidinones
Authors: Petricci Elena , Mugnaini Claudia , Radi Marco , Togninelli Andrea , Bernardini Cesare , Manetti Fabrizio , Parlato Maria Cristina , Renzulli Michela Lucia , Alongi Maddalena , Falciani Chiara , et al. et al. 
Published: May 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Synthetic Applications of Chiral 1,3‐Dioxolan‐4‐ones and 3‐Acyloxazolidin‐5‐ones
Authors: Aitken R. Alan , McGill Steven D. , Power Lynn A. 
Published: May 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
One‐Pot Synthesis of Functionalized Carbacycles by Formal [3 + 3] Cyclizations of 1,3‐Bis(silyl enol ethers) with 1,3‐Dielectrophiles
Authors: Feist Holger , Langer Peter 
Published: May 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
The Photo‐Dehydro‐Diels—Alder (PDDA) Reaction — A Powerful Method for the Preparation of Biaryls
Authors: Wessig Pablo , Mueller Gunnar , Pick Charlotte , Matthes Annika 
Published: May 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Transcriptional Regulation of Metabolic Switching PDK4 Gene under Various Physiological Conditions
Authors: Araki Makoto , Nozaki Yuka , Motojima Kiyoto 
Published: May 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Adrenoleukodystrophy: Structure and Function of ALDP, and Intracellular Behavior of Mutant ALDP with Naturally Occurring Missense Mutations
Authors: Takahashi Norimasa , Morita Masashi , Imanaka Tsuneo 
Published: May 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Uniqueness of the Mucosal Immune System for the Development of Prospective Mucosal Vaccine
Authors: Kunisawa Jun , Gohda Masashi , Kiyono Hiroshi 
Published: May 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
New Solid‐State Chemistry Technologies to Bring Better Drugs to Market — Knowledge‐Based Decision Making
Authors: Park Aeri , Chyall Leonard J. , Dunlap Jeanette , Schertz Christine , Jonaitis David , Stahly Barbara C. , Bates Simon , Shipplett Rex , Childs Scott 
Published: May 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Control of Physical Forms of Drug Particles for Pulmonary Delivery by Spray Drying and Supercritical Fluid Processing
Authors: Tong H. H. Y. , Chow A. H. L. 
Published: May 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
A Review on Molybdenum Determination in Solid Geological Samples
Authors: Das Arabinda K. , Chakraborty Ruma , Cervera M. Luisa , De la Guardia Miguel 
Published: May 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Erratum: MR imaging in assessing cardiovascular interventions and myocardial injury
Authors: Jacquier Alexis , Higgins Charles B , Saeed Maythem 
Published: May 2007

AbstractContrast Media and Molecular Imaging, MR imaging in assessing cardiovascular interventions and myocardial injury, Alexis Jacquier, Charles B. Higgins and Maythem Saeed, published in CMMI 2:1, DOI: 10.1002/cmmi122, pp1–15.Contract/Grant Sponsor information relating to Dr. A. Jacquier was absent from the published article.It should be noted that Dr. A. Jacquier was supported by the Société Française de Radiologie, Paris, as a research fellow.
Analysis of frames by substructuring technique based on using algebraic and graph methods
Authors: Kaveh A. , Fazli H. 
Published: May 2007

AbstractIn this paper, substructuring techniques for the analysis of frame structures by the force method are reviewed. An algorithm is presented for the formation of cycle basis of the graph model of a frame structure. A simple and efficient graph method is proposed for preserving the sparsity of the matrices involved for including the boundary conditions when algebraic and graph force methods are employed. Copyright © 2007 John Wiley & Sons, Ltd.
Spectroelectrochemistry of Carbon Nanostructures
Authors: Kavan Ladislav , Dunsch Lothar 
Published: May 2007

AbstractThis review is focused on charge‐transfer reactions at carbon nanotubes and fullerenes. The spectroelectrochemistry of fullerenes deals with the spin states of fullerenes, the role of mono‐anions and the reactivity of higher charged states in C60. The optical (Vis–NIR) spectroelectrochemistry of single‐walled carbon nanotubes (SWNTs) follows changes in the allowed optical transitions among the Van Hove singularities. The Raman spectroelectrochemistry of SWNT benefits from strong resonance enhancement of the Raman scattering. Here, both semiconducting and metallic SWNTs are analyzed using the radial breathing mode (RBM) and G‐modes as well as the second order (D, G′) and intermediate frequency modes. Raman spectroelectrochemistry of SWNT allows the addressing of index‐identified tubes and even single isolated nanotubes. Optical and Raman spectroelectrochemistry of fullerene peapods, C60@SWNT and C70@SWNT indicates effective shielding of the intratubular fullerene (peas). The most striking effect in the spectroelectrochemistry of peapods is the so‐called “anodic Raman enhancement” of intratubular C60. Double‐walled carbon nanotubes (DWNTs) give a specific spectroscopic response in Vis–NIR spectroelectrochemistry for the inner and the outer tube. They are better distinguishable by Raman spectroelectrochemistry which allows a precise tracing of the specific doping response of outer/inner tubes.
Adsorption Properties of the Penicillin Derivative DTPA on Gold Substrates
Authors: Dreesen Laurent , Silien Christophe , Volcke Cédric , Sartenaer Yannick , Thiry Paul A. , Peremans André , Grugier Jerome , Marchand‐Brynaert Jacqueline , Brans Alain , Grubisic Stana , Joris Bernard 
Published: May 2007

AbstractDespite the large number of articles and patents dealing with penicillin and other β‐lactam antibiotics, there have been no reports about the self‐assembly of such substances as monolayers on gold surfaces. The main reason stems from the high reactivity of the β‐lactam ring, which hinders the development of molecules possessing this entity together with a metal‐anchoring function. Herein, we present the synthesis of a novel molecule, 6‐[(R,S)‐5‐(1,2‐dithiolan‐3‐yl)pentanoyl‐amino]‐penicillanic acid, which combines the β‐lactam ring and a metal‐anchoring group. Using spectroscopic tools, we demonstrate the chemisorption of this compound on gold as self‐assembled monolayers without any alteration of the penicillin pharmacophore and document its reactivity towards a penicillin‐binding protein, BlaR‐CTD. Our work is a preliminary step towards the development of new biosensors and well‐ordered protein arrays, both based on the high affinity of penicillin for penicillin‐binding proteins.
Discrepancy in measuring CD4 expression on T‐lymphocytes using fluorescein conjugates in comparison with unimolar CD4‐phycoerythrin conjugates
Authors: Wang Lili , Abbasi Fatima , Gaigalas Adolfas K. , Hoffman Robert A. , Flagler Dan , Marti G. E. 
Published: May 2007

AbstractBackground:Numerous methods for quantitative fluorescence calibration (QFC) have been developed to quantify receptor expression on lymphocytes. However, the results from the use of these different QFC methods vary considerably in the literature. To better identify the causes of these discrepancies, we measured CD4 expression using FITC and phycoerythrin (PE) conjugates to stain CYTO‐TROL™ Control Cells and T‐lymphocytes in whole blood and isolated cell preparations. We further examined pH of the cellular microenvironment as a cause of discordant results obtained with the FITC conjugate.Methods:Calibration with Quantibrite PE‐labeled microspheres and the use of unimolar CD4‐PE conjugates provided direct measurement of the antibody bound per cell value (ABC) for CD4 expression on normal T‐lymphocytes. Calibration for CD4‐FITC monoclonal antibody (Mab) labeled CYTO‐TROL Control Cells and normal T‐lymphocytes was based on molecules of equivalent soluble fluorochrome (MESF) as determined by FITC‐labeled microspheres traceable to NIST RM 8640. The MESF value for CD4‐FITC Mab was determined that enabled the conversion of the MESF values obtained for CYTO‐TROL cells to ABC. We investigated the likely pH change in the fluorescein microenvironments within FITC‐labeled Mab and cells stained with FITC‐labeled Mab using a pH sensitive indicator.Results:The mean ABC value for T‐lymphocytes prepared from fresh whole blood using CD4‐PE conjugate (48,321) was consistent with previous results, and it was much higher than the mean ABC using CD4‐FITC Mab (22,156). The mean ABC value for CYTO‐TROL cells using CD4‐PE conjugate (43,090) was also higher than that using CD4‐FITC conjugate (34,734), although the discrepancy was not as great. Further studies suggested the discrepancy in CYTO‐TROL results may be accounted for by the low pH of the membrane microenvironment, but the greater discrepancy in T‐lymphocytes could not be fully explained.Conclusion:CD4 expression on fresh normal whole blood samples and CYTO‐TROL cells can be consistently quantified in ABC units using Quantibrite PE quantification beads and unimolar CD4‐PE conjugates. Quantification with CD4‐FITC conjugate is not as consistent, but may be improved by the use of CD4 T‐cells as biological calibrators. This approximation is valid only for surface receptors with consensus ABC values measured by different QFC methods serving as biological standards. Published 2007 Wiley‐Liss, Inc.
Anatomic location defines antigen presentation by dendritic cells to T cells in response to intravenous soluble antigens
Authors: Chung Yeonseok , Chang Jae‐Hoon , Kim Byung‐Seok , Lee Jung‐Mi , Kim Ho‐Youn , Kang Chang‐Yuil 
Published: May 2007

AbstractIn the spleen, exogenous antigen is preferentially presented by CD8α+CD11b– DC to CD8 T cells and by CD8α–CD11b+ DC to CD4 T cells. However, it is not yet clear whether the same rule applies to other secondary lymphoid organs. To address this issue, we first classified secondary lymphoid tissues into three categories based on the expression pattern of CD8α and CD11b in C57BL/6 and BALB/c mice: (a) spleen, (b) mesenteric lymph node (MLN) and (c) other peripheral lymph nodes (PLN). We then analyzed the OVA‐specific T cell‐stimulating capacity of each DC subset after intravenous injection with soluble OVA. Our results show that, regardless of tissue origin, CD8α–CD11b+ DC generally present OVA to CD4 T cells, a finding that held true as well for CD8α+CD11b+ DC in PLN. In striking contrast, CD8α+CD11b– DC in spleen, CD8α–CD11b+ DC in MLN and CD8α+CD11b+ DC in PLN mainly cross‐present OVA to CD8 T cells in their respective tissues. Of note, CD8α–CD11b+ DC in MLN and CD8α+CD11b+ DC in PLN present OVA to both CD4 T and CD8 T cells. Therefore, the antigen‐presenting capacity of each distinct DC subset is determined by its anatomic environment in combination with its surface phenotype.
TLR9 polymorphisms determine murine lymphocyte responses to Helicobacter: Results from a genome‐wide scan
Authors: Anderson Amy E. , Worku Mulugeta L. , Khamri Wafa , Bamford Kathleen B. , Walker Marjorie M. , Thursz Mark R. 
Published: May 2007

AbstractImmune responses to microorganisms in the gastrointestinal tract must be carefully controlled to avoid disease. Helicobacter are Gram‐negative bacteria which cause persistent infection and, in a minority of hosts, peptic ulceration or gastric cancer. Lymphocyte responses are important determinants of the outcome of infection. Therefore, it is important to identify the genetic determinants of lymphocyte responses to this mucosal pathogen. Using a (C57BL/6 × BALB/c) F2 mouse model of Helicobacter infection, we mapped a region of linkage for lymphoproliferation to chromosome 9. Analysis of candidate genes in this region revealed variation of DNA sequence and gene expression in the TLR9 gene between C57BL/6 and BALB/c mouse strains. Reporter assays demonstrated higher levels of TLR9 transcriptional activity and increased NF‐κB activation associated with the C57BL/6 TLR9 promoter and coding sequences. The importance of TLR9 in the control of lymphocyte responses was confirmed by demonstrating that lymphoproliferation and IFN‐γ secretion was diminished in the TLR9–/– mouse. Furthermore, neutrophil infiltration of the gastric epithelium is reduced in the absence of TLR9. Regulation of TLR9 expression and signalling therefore appears to play an important role in the control of lymphocyte responses to Helicobacter and potentially other luminal microorganisms.