bluuebunny/crossref_metadata_2025_split huggingface dataset:
Synthesis and Mechanism of 1D ZnO Based on Alkaline Dissolution‐Conversion Strategy of High Stable and Soluble ɛ‐Zn(OH)2
Authors: Lin Shuyu , Wu Zhi‐Hai , Yang Fan , Fu Jin , Yu Yang‐Xin , Wang Jing , Xiang Lan 
Published: March 2024

AbstractA high soluble and stable ɛ‐Zn(OH)2 precursor is synthesized at below room temperature to efficiently prepare ZnO whiskers. The experimental results indicate that the formation of ZnO whiskers is carried out mainly via two steps: the formation of ZnO seeds from ɛ‐Zn(OH)2 via the in situ solid conversion, and the following growth of whiskers via dissolution‐precipitation route. The decrease of temperature from 25 to 5 °C promotes the formation of ɛ‐Zn(OH)2 with higher solubility and stability, which balances the conversion and dissolution rates of precursor. The Rietveld refinement, DFT calculations and MD simulations reveal that the primary reason for these characteristics is the expansion of ɛ‐Zn(OH)2 lattice due to temperature, causing difficulties in the dehydration of adjacent ─OH. Simultaneously, the larger specific surface area favors the dissolution of ɛ‐Zn(OH)2. Based on this precursor, well‐dispersed ZnO whiskers with 9.82 µm in length, 242.38 nm in diameter, and an average aspect ratio of 41 are successfully synthesized through a SDSN‐assisted hydrothermal process at 80 °C. The process has an extremely high solid content of 2.5% (mass ratio of ZnO to solution) and an overall yield of 92%, which offers a new approach for the scaled synthesis of high aspect ratio ZnO whiskers by liquid‐phase method.
Decoupling the Synergy Between PGM and PGM‐Free Moieties toward Oxygen Reduction Reaction
Authors: Zhou Yangdong , Li Jiayang , Wu Qiaojing , Wang Ning , Xing Lixin , Wang Liguang , Du Lei , Ye Siyu 
Published: March 2024

AbstractRecently, coupling the conventional low Pt‐group‐metal (low‐PGM, LP) and emerging PGM‐free (PF) moiety to form a composite LP/PF catalyst is proposed to be an advanced strategy to improve the intrinsic activity and stability of oxygen reduction reaction (ORR) catalysts. Milestones in terms of ORR mass activity are created by this type of catalyst. However, the specific synergy between LP and PF moieties has not been well elucidated. Herein, two model catalysts are synthesized, i.e., atomically dispersed Co/N/C supporting Pt single atoms (Co/N/C@Pt‐SAs) and PtCo nanoparticles (Co/N/C@PtCo‐NPs). Interestingly, the Co/N/C@PtCo‐NPs catalyst presents higher ORR mass activity prior to Co/N/C@Pt‐SAs. This is theoretically due to the dual “built‐in electric field” in Co/N/C@PtCo‐NPs: one electric field with a direction from Pt to Co in NPs and another from Pt to Co/N/C; that is, Pt gains higher electron density in Co/N/C@PtCo‐NPs than that in Co/N/C@Pt‐SAs, thus forming an asymmetric electron cloud, and regulating the adsorption and activation of oxygen‐containing species. In addition, the existence of Co significantly decreases the average valence state of PtCo NPs, indicating a stronger affinity between PtCo NPs and Co/N/C substrate, to account for the enhanced stability.
Structural Control Enables Catalytic and Electrocatalytic Activity of Porous Tetrametallic Nanorods
Authors: Zámbó Dániel , Kovács Dávid , Radnóczi GyörgyZ. , Horváth Zsolt E. , Sulyok Attila , Tolnai István , Deák András 
Published: March 2024

AbstractIntegrating more than one type of metal into a nanoparticle that has a well‐defined morphology and composition expands the functionalities of nanocatalysts. For a metal core/porous multimetallic shell nanoparticle, the availability of catalytically active surface sites and molecular mass transport can be enhanced, and the multielemental synergy can facilitate intraparticle charge transport. In this work, a reliable and robust synthesis of such a functional tetrametallic nanoparticle type is presented, where a micro‐ and mesoporous PdPtIr shell is grown on Au nanorods. The effect of critical synthesis parameters, namely temperature and the addition of HCl are investigated on the hydrodynamic size of the micellar pore template as well as on the stability of the metal chloride complexes and various elemental analysis techniques prove composition of the porous multimetallic shell. Due to the synergistic properties, the tetrametallic nanorods possess extensive negative surface charge making them a promising catalyst in reduction reactions. Dye degradation as well as the conversion of p‐nitrophenol to p‐aminophenol is catalyzed by the supportless nanorods without light illumination. By depositing the particles onto conductive substrates, the nanostructured electrodes show promising electrocatalytic activity in ethanol oxidation reaction. The nanocatalyst presents excellent morphological stability during all the catalytic test reactions.
Highly Active CoNi‐CoN3 Composite Sites Synergistically Accelerate Oxygen Electrode Reactions in Rechargeable Zinc–Air Batteries
Authors: Li Nan , Sun Mingzi , Xiao Jiaxiang , Ma Xiaoyu , Huang Lijuan , Li Hongyu , Xie Chao , Yang Yahui , Jiang Hao , Huang Bolong , Zhang Wenjun 
Published: March 2024

AbstractReaching rapid reaction kinetics of oxygen reduction (ORR) and oxygen evolution reactions (OER) is critical for realizing efficient rechargeable zinc–air batteries (ZABs). Herein, a novel CoNi‐CoN3 composite site containing CoNi alloyed nanoparticles and CoN3 moieties is first constructed in N‐doped carbon nanosheet matrix (CoNi‐CoN3/C). Benefiting from the high electroactivity of CoNi‐CoN3 composite sites and large surface area, CoNi‐CoN3/C shows a superior half‐wave potential (0.88 V versus RHE) for ORR and a small overpotential (360 mV) for OER at 10 mA cm−2. Theoretical calculations have demonstrated that the introduction of CoNi alloys has modulated the electronic distributions near the CoN3 moiety, inducing the d‐band center of CoNi‐CoN3 composite site to shift down, thus stabilizing the valence state of Co active sites and balancing the adsorption of OER/ORR intermediates. Accordingly, the reaction energy trends exhibit optimized overpotentials for OER/ORR, leading to superior battery performances. For aqueous and flexible quasi‐solid‐state rechargeable ZABs with CoNi‐CoN3/C as catalyst, a large power density (250 mW cm−2) and high specific capacity (804 mAh g−1) are achieved. The in‐depth understanding of the electroactivity enhancement mechanism of interactive metal nanoparticles and metal coordinated with nitrogen (MNx) moieties is crucial for designing novel high‐performance metal/nitrogen‐doped carbon (M─N─C) catalysts.
Recent overview of microextraction of metal ions and pharmaceuticals by solidified floating organic drop microextraction techniques
Authors: Kumar Shivam , Satapathy Sourabh , Kurmi Balak Das , Gupta Ghanshyam Das , Patel Preeti 
Published: March 2024

AbstractThis work presents a comprehensive overview of solidified floating organic drop microextraction, with a particular emphasis on its applications in the analysis of heavy metal ions and different pharmaceutical compounds by sample pretreatment, complexation, and their identification by various analytical techniques. Here, we discussed basic principles, procedures, applications of the technique, and effects of different variables like pH, temperature, stirring rate, extraction time, salts addition, extraction solvent and extraction volume, centrifugation speed, and, vortex time on preconcentration. In brief, the review summarises the various modes of solidified floating organic drop microextraction such as dispersive liquid‐liquid microextraction, ultrasound‐assisted, air‐assisted liquid‐liquid microextraction, and vortex‐assisted solidified floating organic drop microextraction. this review covers the methods combined with analytical techniques such as inductively coupled plasma‐optical emission spectrometry, electrothermal atomic absorption spectrometry, flame atomic absorption spectroscopy, graphite furnace atomic absorption spectrometry, electrothermal vaporization inductively coupled plasma mass spectrometry, high‐performance liquid chromatography, and gas chromatography/mass spectrometry. among these, the incorporation of ultrasonic, vortex, and air agitation improves the dispersion mechanism. The coupling of solidified floating organic drop microextraction with other techniques enhances the selectivity and efficiency of the preconcentration procedure. This review provides a potential overview of the fundamental principles, advancements in various modes, influencing factors, and applications of solidified floating organic drop microextraction, showing its potential for advancements in sample preparation and analytical methodologies across various domains.
Triphenyl phosphate interferes with the synthesis of steroid hormones through the PPARγ/CD36 pathway in human trophoblast JEG‐3 cells
Authors: Chen Yuting , Liu Qian , Wang Yao , Jiang Mengzhu , Zhang Jing , Liu Yuguo , Lu Xiaoxun , Tang Huanwen , Liu Xiaoshan 
Published: March 2024

AbstractTriphenyl phosphate (TPhP), a chemical commonly found in human placenta and breast milk, has been shown to disturb the endocrine system. Our previous study confirmed that TPhP could accumulate in the placenta and interference with placental lipid metabolism and steroid hormone synthesis, as well as induce endoplasmic reticulum (ER) stress through PPARγ in human placental trophoblast JEG‐3 cells. However, the molecular mechanism underlying this disruption remains unknown. Our study aimed to identify the role of the PPARγ/CD36 pathway in TPhP‐induced steroid hormone disruption. We found that TPhP increased lipid accumulation, total cholesterol, low‐ and high‐density protein cholesterol, progesterone, estradiol, glucocorticoid, and aldosterone levels, and genes related to steroid hormones synthesis, including 3βHSD1, 17βHSD1, CYP11A, CYP19, and CYP21. These effects were largely blocked by co‐exposure with either a PPARγ antagonist GW9662 or knockdown of CD36 using siRNA (siCD36). Furthermore, an ER stress inhibitor 4‐PBA attenuated the effect of TPhP on progesterone and glucocorticoid levels, and siCD36 reduced ER stress‐related protein levels induced by TPhP, including BiP, PERK, and CHOP. These findings suggest that ER stress may also play a role in the disruption of steroid hormone synthesis by TPhP. As our study has shed light on the PPARγ/CD36 pathway's involvement in the disturbance of steroid hormone biosynthesis by TPhP in the JEG‐3 cells, further investigations of the potential impacts on the placental function and following birth outcome are warranted.
The CPB Sight Words: A New Research‐Based High‐Frequency Wordlist for Early Reading Instruction
Authors: Green Clarence , Keogh Kathleen , Prout Julia 
Published: March 2024

AbstractThis paper focuses on one of the most widely used resources by reading teachers during early‐emergent literacy, the high‐frequency wordlists commonly called ‘sight words. Existing sight word resources available to teachers are extremely outdated and/or methodologically unsound. In this Teaching and Learning in Action article, a new research‐based list of high‐frequency words is released for teachers, the Children’s Picture Book Sight Words (cpb sight words).
First case of nodular dermatofibrosis with cystic renal disease in a beagle: An atypical case without FLCN gene mutation
Authors: Gómez‐Barris Belén Rivera , Balazs Veronica , Villamar Katherine Chaguay , Toro‐Valdivieso Constanza 
Published: March 2024

AbstractThis report presents the first case of nodular dermatofibrosis with renal cysts (NDRC) in a beagle. In this atypical case, the gene mutation associated with the disease was not present, the renal cysts showed dynamic changes in size and number, and the patient has greatly surpassed the NDRC life expectation.
Intensive Blood Pressure Control After Endovascular Thrombectomy for Acute Ischemic Stroke: a Systematic Review and Meta-Analysis
Authors: Abuelazm Mohamed , Khildj Yehya , Ibrahim Ahmed A. , Mahmoud Abdelrahman , Amin Ahmed Mazen , Gowaily Ibrahim , Khan Ubaid , Abdelazeem Basel , Brašić James Robert 
Published: March 2024

Abstract
Background and Purpose
Optimal clinical outcome with successful recanalization from endovascular thrombectomy (EVT) requires optimal blood pressure (BP) management. We aimed to evaluate the efficacy and safety of the intensive BP target (< 140 mm Hg) versus the standard BP target (< 180 mm Hg) after EVT for acute ischemic stroke.

Methods
We conducted a systematic review and meta-analysis synthesizing evidence from randomized controlled trials (RCTs) obtained from PubMed, Embase Cochrane, Scopus, and WOS until September 7th, 2023. We used the fixed-effect model to report dichotomous outcomes using risk ratio (RR) and continuous outcomes using mean difference (MD), with a 95% confidence interval (CI). PROSPERO ID: CRD42023463206.

Results
We included four RCTs with 1559 patients. There was no difference between intensive BP and standard BP targets regarding the National Institutes of Health Stroke Scale (NIHSS) change after 24 h [MD: 0.44 with 95% CI (0.0, 0.87), P = 0.05]. However, the intensive BP target was significantly associated with a decreased risk of excellent neurological recovery (mRS ≤ 1) [RR: 0.87 with 95% CI (0.76, 0.99), P = 0.03], functional independence (mRS ≤ 2) [RR: 0.81 with 95% CI (0.73, 0.90), P = 0.0001] and independent ambulation (mRS ≤ 3) [RR: 0.85 with 95% CI (0.79, 0.92), P < 0.0001].

Conclusions
An intensive BP target after EVT is associated with worse neurological recovery and significantly decreased rates of functional independence and independent ambulation compared to the standard BP target. Therefore, the intensive BP target should be avoided after EVT for acute ischemic stroke.
Influence of abdominal fat distribution and inflammatory status on post-operative prognosis in non-small cell lung cancer patients: a retrospective cohort study
Authors: Ma Mengtian , Luo Muqing , Liu Qianyun , Zhong Dong , Liu Yinqi , Zhang Kun 
Published: March 2024

Abstract
Purpose
To evaluate the influence of visceral fat area (VFA), subcutaneous fat area (SFA), the systemic immune-inflammation index (SII) and total inflammation-based systemic index (AISI) on the postoperative prognosis of non-small cell lung cancers (NSCLC) patients.

Methods
266 NSCLC patients received surgery from two academic medical centers were included. To assess the effect of abdominal fat measured by computed tomography (CT) imaging and inflammatory indicators on patients’ overall survival (OS) and progression-free survival (PFS), Kaplan–Meier survival analysis and Cox proportional hazards models were used.

Results
Kaplan–Meier analysis showed the OS and PFS of patients in high-VFA group was better than low-VFA group (p < 0.05). AISI and SII were shown to be risk factors for OS and PFS (p < 0.05) after additional adjustment for BMI (Cox regression model II). After further adjustment for VFA (Cox regression model III), low-SFA group had longer OS (p < 0.05). Among the four subgroups based on VFA (high/low) and SFA (high/low) (p < 0.05), the high-VFA & low-SFA group had the longest median OS (108 months; 95% CI 74–117 months) and PFS (85 months; 95% CI 65–117 months), as well as the lowest SII and AISI (p < 0.05). Low-SFA was a protective factor for OS with different VFA stratification (p < 0.05).

Conclusion
VFA, SFA, SII and AISI may be employed as significant prognostic markers of postoperative survival in NSCLC patients. Moreover, excessive SFA levels may encourage systemic inflammation decreasing the protective impact of VFA, which may help to provide targeted nutritional support and interventions for postoperative NSCLC patients with poor prognosis.
Fractionation of wood due to industrial chipping: effects and potential for Kraft pulping of European spruce
Authors: Poschner Roman , Czibula Caterina , Bakhshi Adelheid , Harter Thomas , Eckhart Rene , Hirn Ulrich 
Published: March 2024

AbstractThe research conducted on kraft cooking of for different chip sizes is often not representative for the industrial process since the chip size fractions were made of high-quality wood without impurities. We evaluated the effects and the potential of cooking non ideal spruce chip fractions after industrial chipping and screening. The chips were classified according to SCAN 40:01, and the respective fractions were cooked under the identical conditions to mimic the effect of a joint cooking in the industrial digester. For the undersized chips we found higher bark content, a lower screened yield, a higher Kappa number, lower fiber length and lower tensile strength. For the oversized chips, the fiber length and tensile index were also considerably lower. A lower wood quality due to high knot content in the larger fractions was found to be the reason for that. Based on the data obtained from the experiments and literature, different process options for increased yield and reduced chemical consumption are discussed, e.g., separate cooking of different chip fractions. Improved chip screening seems to be the process improvement with lowest costs and highest impact.
Employing zero-inflated beta distribution in an exposure-response analysis of TYK2/JAK1 inhibitor brepocitinib in patients with plaque psoriasis
Authors: Tsamandouras Nikolaos , Qiu Ruolun , Hughes Jim H. , Sweeney Kevin , Prybylski John P. , Banfield Christopher , Nicholas Timothy 
Published: March 2024

AbstractBrepocitinib is an oral selective dual TYK2/JAK1 inhibitor and based on its cytokine inhibition profile is expected to provide therapeutic benefit in the treatment of plaque psoriasis. Efficacy data from a completed Phase 2a study in patients with moderate-to-severe plaque psoriasis were utilized to develop a population exposure-response model that can be employed to inform dose selection decisions for further clinical development. A modeling approach that employs the zero-inflated beta distribution was used to account for the bounded nature and distributional characteristics of the Psoriasis Area and Severity Index (PASI) score data. The developed exposure-response model provided an adequate description of the observed PASI scores across all the treatment arms tested and across both the induction and maintenance dosing periods of the study. In addition, the developed model exhibited a good predictive capacity with regard to the derived responder metrics (e.g., 75%/90%/100% improvement in PASI score [PASI75/90/100]). Clinical trial simulations indicated that the induction/maintenance dosing paradigm explored in this study does not offer any advantages from an efficacy perspective and that doses of 10, 30, and 60 mg once-daily may be suitable candidates for clinical evaluation in subsequent Phase 2b studies.
A new approach to the multiple obnoxious facility location problem based on combinatorial and continuous tools
Authors: Locatelli M. 
Published: March 2024

AbstractIn this paper we address the multiple obnoxious facility location problem. In this problem p facilities need to be spread within the unit square in such a way that they are far enough from each other and that their minimal distance from n communities, with known positions within the unit square, is maximized. The problem has a combinatorial component, related to the key observation made in Drezner (Omega 87:105–116, 2019) about the role played by Voronoi points. We propose a new approach, which exploits both the combinatorial component of the problem and, through continuous local optimizations, also its continuous component. We also propose techniques to limit the impact on computation times of the number n of communities. The approach turns out to be quite competitive and is able to return 24 new best known solutions with respect to the best results reported in Kalczynski (Optim Lett 16:1153–1166, 2022).
Learning analytics in mathematics education: the case of feedback use in a digital classification task on reflective symmetry
Authors: Hershkovitz Arnon , Noster Norbert , Siller Hans-Stefan , Tabach Michal 
Published: March 2024

AbstractLearning Analytics is concerned with the use of data collected in educational settings to support learning processes. We take a Learning Analytics approach to study the use of immediate feedback in digital classification tasks in mathematics. Feedback serves as an opportunity for learning, however its mere existence does not guarantee its use and effectiveness, as what matters is how learners interact with it. Therefore, our research questions are focused on that interaction. The data consisted of 266 object movements for classifying polygons, and 524 shape movements for classifying traffic signs, under the topic of symmetry. Participants included 29 elementary school students (9–12 years old) from Israel and Germany. Analyzing students’ success, feedback use, and the associations between them, we demonstrate how not acting upon feedback is negatively associated with success, and how this undesired behavior slightly reduces along the learning process.
Promoting the itemized educational spending of rural coastal households in Bangladesh through unconditional cash and food assistance
Authors: Bari Md. Abdul , Khan Ghulam Dastgir , Yoshida Yuichiro , Kusakabe Tatsuya 
Published: March 2024

AbstractThe vulnerable households in the rural coastal regions of Bangladesh have been suffering from chronic poverty because of a lack of resources to invest in the human capital development, such as education and training. The unconditional cash and food (UCF) assistance programs in Bangladesh have been designed to combat chronic poverty. This study examines the impact of the UCF assistance receipt on the itemized educational spending: the total spending on education, school tiffin, educational stationery, uniforms, admission fees, examinations, textbooks, education-related Internet, and education-related transportation by the households. A Fuzzy regression discontinuity design (RDD) is used as an identification strategy, in which the assignment variable is the land ownership by the households. The RDD method is based on the idea that the households just below and above the cutoff of the assignment variable are locally randomized, therefore free from any selection bias. The results consistently show that the UCF assistance increases the spending on all educational items, except for textbooks and education-related transportation. This study suggests that the UCF assistance can be used as a policy tool to accelerate the sustainable development goal of inclusive quality education for rural coastal areas by increasing the itemized spending on education.