bluuebunny/crossref_metadata_2025_split huggingface dataset:
The impact of temperature changes on the health vulnerability of migrant workers: an empirical study based on the China family panel studies
Authors: Liang Ting , Ai Zilin , Zhong Hui , Xiao Mengyan , Xie Mengzhou , Liang Xiaoli , Li Liang 
Published: February 2025

IntroductionMigrant workers constitute a significant portion of China’s workforce, and their health directly affects labor supply and economic stability. Health vulnerability plays a crucial role in shaping the well-being of migrant workers, yet its determinants, particularly the impact of temperature change, remain underexplored. This study, based on the socio-ecological model, investigates how temperature variations influence the health vulnerability of migrant workers in China.MethodsUsing data from 2020, this study quantifies health vulnerability and examines the impact of temperature fluctuations across different seasons. Robustness checks, including dependent variable substitutions and model modifications, ensure the reliability of the findings. Furthermore, a mechanism analysis is conducted to explore the underlying pathways through which temperature change affects health vulnerability.ResultsThe findings reveal that rising temperatures in spring, summer, and winter significantly exacerbate the health vulnerability of migrant workers, while increasing autumn temperatures mitigate it. Mechanism analysis identifies heightened psychological burden as a key channel through which temperature change worsens health vulnerability. Additionally, generational differences emerge: older migrant workers are more adversely affected by elevated spring temperatures, whereas younger workers exhibit greater sensitivity to rising summer temperatures.DiscussionThese results underscore the necessity of targeted health interventions and adaptive labor protection policies. By highlighting the seasonal and generational disparities in the effects of temperature change, this study offers theoretical and empirical support for enhancing the resilience of migrant workers to climate variations. The findings provide valuable insights for policymakers in designing strategies to safeguard the health and stability of the migrant workforce.
Early functional proprioceptive stimulation in high spinal cord injury: a pilot study
Authors: Martinache Florence , de Crouy Anne-Claire , Boutin Arnaud , Duranteau Jacques , Vigué Bernard 
Published: February 2025

IntroductionThe first months following a spinal cord injury (SCI) are crucial for promoting recovery. However, patients with high SCIs often require prolonged stays in intensive care units (ICUs), delaying optimal rehabilitation due to limited resources. This study examined the safety, feasibility, and effects on spasticity and muscle atrophy of an early rehabilitation technique using non-invasive sensory stimulation and called functional proprioceptive stimulation (FPS).Materials and methodsTen SCI patients were included in this randomized pilot study, with five receiving early FPS and five receiving sham stimulation. Both groups were treated using the Vibramoov, consisting of 12 computer-synchronized vibrators placed on the lower limbs. Treatment sessions lasted 30 min, four times a week, for up to 8 weeks. Spasticity was assessed using the Modified Ashworth Scale, Tardieu Scale, Spinal Cord Assessment Tool for Spastic Reflexes, and a patient self-evaluation with a visual analog scale. Muscle atrophy was evaluated through ultrasonography of rectus femoris thickness and cross-sectional area. The duration of the follow-up period ranged from 6 months to 1 year.ResultsTreatment began early, with a median of 4 days post-injury for both groups. The number of adverse events was similar between groups, with none linked to the intervention. No medium-term effects on spasticity or muscle atrophy could be identified. However, our results show a tendency toward a beneficial short-term effect of FPS on spasticity, observed for all spasticity measurements.DiscussionThis pilot study shows that early FPS is feasible and safe for SCI as early as the intensive care unit stage. We demonstrated that FPS induced a transient relaxation and spasticity reduction that could potentially enhance a rehabilitation session administered shortly after it, but larger studies are needed to determine the medium and long-term effects.
Clinical Trial RegistrationClinicalTrials.gov, identifier (NCT05094752)
Cost and affordability of the food basket in the Republic of Moldova
Authors: Siminiuc Rodica , Țurcanu Dinu , Siminiuc Sergiu 
Published: February 2025

IntroductionFood and nutrition security remain among humanity's most urgent challenges, with 23.5% of Moldova's population experiencing food insecurity. Despite the critical nature of this issue, national-level research on nutritional security remains scarce. This study aims to evaluate the cost and accessibility of minimum consumption and healthy food baskets in Moldova to better understand affordability constraints and inform policy interventions.MethodsThe study assesses the cost and affordability of food baskets by calculating their cost as a proportion of the country's minimal subsistence amount and evaluating affordability using the International Poverty Line (IPL) criterion. The analysis focuses on two key food baskets: the Minimum Consumption Food Basket (MCFB) and the Healthy Food Basket (HFB).ResultsFindings indicate that ~52% of the population lacks access to the MCFB, while 78.6% cannot afford the HFB without reallocating non-food expenses. Affordability gaps were most pronounced among lower-income households, highlighting significant vulnerabilities within specific socio-demographic groups.DiscussionThese results underscore the urgent need for policies addressing food affordability and accessibility in Moldova. Strengthening national strategies to align with Sustainable Development Goals (SDGs) 2 (Zero Hunger) and 3 (Good Health and Wellbeing) could help mitigate food insecurity risks. By addressing affordability gaps and ensuring equitable access to nutritious food, these strategies can support national development priorities and enhance food security resilience.
CT- and MRI-based volumetry for Chiari-like malformation and syringomyelia in Pomeranians
Authors: Santifort Koen M. , Carrera Ines , Mandigers Paul J. J. 
Published: February 2025

IntroductionVolumetric studies in relation to CM/SM have not been reported in Pomeranians. In this study, we aim to (1) report the intermodality agreement between CT- and MRI-based volumetric measurements of the skull and cervical spinal canal, and (2) assess for differences and associations between the volumetric measurements and CM/SM status.MethodsPomeranians were included that underwent CT and MRI studies during the period of February 2022–June 2024. Frontal sinus volume (FSV), caudal cranial fossa volume (CCFV), rostral and middle cranial fossa volume (RMCFV), caudal cranial fossa parenchymal volume (CCFPV), rostral and middle cranial fossa parenchymal volume (RMCFPV), cerebellar parenchymal volume (CPV), brain stem parenchymal volume (BSPV), ventricular system volume (VSV), and spinal canal volume between C1-C7 (CSCV) were measured. CCFV to RMCFV volume index (VI) and CCFPV to CCFV (CCFPV%) were calculated. Agreement between MRI- and CT-based quantitative measurements was assessed with intraclass correlation coefficients. Inferential statistical tests including logistic regression modeling were performed to assess for associations between variables and CM/SM status.ResultsFor all volumetric assessments that were performed on both CT and MRI, agreement was good or excellent. There were significant differences between SM normal and abnormal dogs for body weight as well as all volumetric parameters except for CCFPV% and RMCFV. Multiple logistic regression showed that a smaller CCFV and larger VSV were associated with SM.ConclusionSmaller CCFV and larger VSV are associated with the development of SM in Pomeranians and have increased odds of SM.
Prevalências de falha terapêutica e mortalidade em PVHA hospitalizadas em hospital universitário da Região Norte do Brasil
Authors: Lopes Carmen Andréa Freitas , Gomes Henrique Guimarães 
Published: February 2025

Human immunodeficiency vírus (HIV) é um retrovírus que acomete o sistema imune e pode causar a síndrome de imunodeficiência adquirida (SIDA), predispondo infecções oportunistas e neoplasias. Este pode alcançar diretamente órgãos alvos comprometendo principalmente sistema nervoso central, cardiovascular e renal, impactando em síndrome demencial, aumento do risco cardiovascular e insuficiência renal, respectivamente. O presente estudo, transversal com amostra não probabilística de 206 Pessoas Vivendo com HIV/AIDS (PVHA) que foram hospitalizadas, se propôs ao estimar o itinerário terapêutico destas pessoas, identificar as prevalências de falha terapêutica, resistência genotípica secundária do HIV e o desfecho óbito expresso em taxa de mortalidade. Os dados foram coletados mediante registros em prontuários e consultas no LAUDO AIDS (sistema on-line do Ministério da Saúde). A população estudada foi predominantemente do gênero masculino, com mediana de idade de 40 anos, apesentando vulnerabilidade social e estágios avançados da infecção pelo HIV. Sessenta e quatro por cento dos pacientes possuíam contagem de células TCD4 inferior a 200 células e 45,3% tinham cargas virais acima de 100.000 cópias de HIV-RNA. A prevalência de falha terapêutica foi de 29,7% e de resistência genotípica secundária foi de 15,7%, observando-se uma taxa de mortalidade de 24,3% em uma população cujo itinerário terapêutico mediano foi de 7 dias. Portanto, trata-se de uma população com grande vulnerabilidade socioeconômica e doença avançada pelo HIV, assim como elevadas taxas de resistência genotípica, falha terapêutica e mortalidade e com elevada quantidade de pacientes diagnosticados recentemente.
Análise do painel de transplantes no Rio de Janeiro nos três primeiros trimestres de 2023
Authors: Carvalho Maria Luiza Marcondes , Ferreira Priscilla Cristina Lopes , Silva Lohrane Menezes da , Tuza Fábio Augusto D’ Alegria , Lucena Glauco Macêdo de , Silva Gabrielle Lucas da , Cunha Paula , Couto Victor Rodrigues da Fonseca de Souza , Gomes João Márcio Nunes , Rios Danielle Camara de Vasconcelos 
Published: February 2025

O maior programa público de transplante de órgãos, tecidos e células do mundo é brasileiro. Este é garantido a toda a população por meio do Sistema Único de Saúde, responsável pelo financiamento de mais de 85% dos transplantes no país. Objetiva-se entender a dinâmica, entre a oferta e a demanda, da transplantação realizada no território brasileiro, mais especificamente no Rio de Janeiro, nos três primeiros trimestres de 2023. Trata-se de um estudo ecológico, retrospectivo, descritivo acerca dos dados de transplante de tecidos e órgãos disponibilizados pelo Registro Brasileiro de Transplantes. O estudo foi feito a partir de dados secundários, baseado nos elementos apresentados pelo sistema de transplantes do território, sendo feito um recorte no estado do Rio de Janeiro, entre os meses de janeiro a setembro de 2023. Percebe-se que o número total de transplantes no território brasileiro, durante os meses de janeiro a setembro de 2023, foi de 6.559, contabilizando coração, fígado, intestino e entre outros. Sendo que os tecidos e a córnea foram transplantados 12.014 no total e o de medula óssea foram 3.062. Portanto, notamos que os principais órgãos transplantados foram rins, fígado e coração em todo o território brasileiro. Entretanto, a maior demanda à nível nacional é de rim e no RJ córnea. A oferta de órgãos e tecidos é proveniente, na maioria das vezes, de pacientes que sofreram morte encefálica, sendo os homens mais acometidos.
Pengembangan Sediaan Emulgel Ekstrak Etanol Teh Putih dan Minyak Biji Delima dengan Aktivitas Antioksidan dan Fotoprotektif
Authors: Priani Sani Ega , Syafnir Livia , Mulkiya Kiki , Fitrianingsih Sri Peni , Radina Faqih 
Published: February 2025

White tea and pomegranate seed oil are known to contain many bioactive compounds that make them potentially have antioxidant and photoprotective activities. This study aimed to examine the antioxidant and photoprotective activities of white tea leaf extract and develop it in an emulgel dosage form. White tea is extracted with 70% ethanol at 600C. The extracts were tested for antioxidant activity by the DPPH method and for photoprotective activity by the Mansur method. White tea extract was developed into an emulgel with pomegranate seed oil as the oil phase, stearic acid and TEA as emulsifiers, and viscolam mac 10 as a gelling agent. The results showed that the ethanol extract of white tea had a very strong antioxidant activity with an IC50 value of 10.80 ± 0.75 ppm. White tea ethanol extract also has photoprotective activity with an SPF value of 12.35 ± 0.63, %Te value of 2.13 ± 0.01 %, and %Tp value of 45.13 ± 0.08 % (ultra protection category). White tea extract has been successfully developed into an emulgel preparation with good characteristics and stability in terms of organoleptic, pH, viscosity, spreadability, and rheological behavior. White tea emulgel are stable based on centrifugation and freeze-thaw tests.
Pengaruh Kemoterapi terhadap Kadar Hematologi pada Pasien Kanker Payudara di RSUD dr. Kanujoso Djatiwibowo Balikpapan
Authors: Nabilah Annisa , Prabowo Wisnu Cahyo , Kuncoro Hadi 
Published: February 2025

Kanker payudara merupakan penyakit keganasan pada jaringan payudara yang dapat berasal dari epitel duktus maupun lobulusnya. Terapi kanker payudara dapat dilakukan dengan beberapa macam terapi, salah satunya adalah kemoterapi. Efek samping kemoterapi yang paling umum adalah mielosupresi yaitu penurunan kadar sel darah karena agen kemoterapi bersifat toksik terhadap organ pembentuk darah. Penelitian ini dilakukan untuk mengetahui gambaran pengaruh kemoterapi dalam menurunkan kadar sel darah pasien kanker payudara yang menerima kemoterapi di RSUD dr. Kanujoso Djatiwibowo Balikpapan periode Juli 2022 sampai Juni 2023. Penelitian ini bersifat deskriptif dengan desain cross-sectional. Dari 82 sampel, pasien dengan kadar eritrosit dibawah normal sebanyak 50 pasien (60%); hemoglobin 79 pasien (96%); hematokrit 75 pasien (91%); neutrofil 20 pasien (24%); leukosit 25 pasien (30%); dan trombosit 7 pasien (9%). Kadar hematologi di bawah normal paling banyak adalah hemoglobin dan hematokrit
Aktivitas Peningkatan Fagositosis Sel Makrofag oleh Ekstrak Etanol Buah Etlingera rubroloba A.D. Poulsen Pada Mencit Yang Distimulasi Antigen Mtb
Authors: Badia Esti , Yulianti Sri Samrina , Rusli Nirwati , Jabbar Asriullah , Malaka Muhammad Hajrul , Sahidin Idin , Ilyas Y. Muhammad 
Published: February 2025

Peningkatan aktivitas fagositosis sel makrofag sangat dibutuhkan oleh penderita penyakit tubekulosis (TB) untuk melawan invasi patogenitas dari bakteri Mycobacterium tuberculosis (Mtb) dan mengatasi keparahan infeksi sehingga pengobatan akan lebih optimal. Pengoptimalan fagositosis sel makrofag dengan pemberian imunostimulator dari tumbuhan seperti buah Etingera rubroloba A.D Poulsen penting diungkap. Buah diyakini sebagai imunostimulator berdasarkan penggunaan empiris oleh masyarakat Sulawesi Tenggara untuk memelihara daya tahan tubuhnya serta menyembuhkan penyakit infeksi demam typhoid, dan secara ilmiah terbukti sebagai imunomodulator, antiinflamasi dan antioksidan. Tujuan penelitian ini adalah membuktikan aktivitas buah E. rubroloba meningkatkan aktivitas fagositosis sel makrofag pada penyakit TB. Jenis penelitian ini eksperimental menggunakan 30 ekor mencit jantan yang terdiri dari kelompok normal (tanpa infeksi Mtb), kelompok negatif (Na.CMC 0.5% + infeksi Mtb), kelompok positif (ekstrak meniran komersial + infeksi Mtb), kelompok ekstrak dosis 200 mg/kg BB + infeksi Mtb, kelompok ekstrak dosis 300 mg/kg BB + infeksi Mtb, kelompok ekstrak dosis 400 mg/kg BB + infeksi Mtb. Hewan uji diberikan perlakuan selama 7 hari dan pada hari ke-8 diinfeksi antigen Mtb (Esat-6) secara intra perintonium. Peningkatan fagositosis sel makrofag dihitung dengan mikroskop, selanjutnya data yang diperoleh dianalisis statistik one way ANOVA dan uji post hoc tukey. Hasil penelitian menunjukan ekstrak etanol buah E.rubroloba terbukti meningkatkan aktivitas fagositosis sel makrofag pada mencit distimulasi Mtb yang berbeda signifikan dengan kontrol negatif (P<0.05). Penelitian ini berhasil mengungkap informasi ilmiah baru dari tumbuhan E.rubroloba sebagai imunostimulator pada infeksi TB, sehingga berpotensi dikembangkan sebagai agen imunostimulator baru pada penyakit TB.
Education on Indicators of Clean and Healthy Living Behavior in the Powelua Village Community, Donggala Regency, Central Sulawesi
Authors: Palipadang Matra Novalia , Dipayana I Made , Fince Maria , Ferdelita Putri 
Published: February 2025

Clean and Healthy Living Behavior (PHBS) is a form of manifestation of healthy living orientation in individual, family and community culture, which aims to improve, maintain and protect health both physically, mentally, spiritually and socially. Clean and healthy living behavior is an effort to strengthen a person, group or community to care about and prioritize creating a higher quality life. To make this happen, it is necessary to educate the community about the implementation of PHBS. Community service aims to provide information about PHBS to increase knowledge and attitudes about the implementation of PHBS in the community. The method of implementing the service is a lecture using visual media in the form of a leaflet about 10 indicators of clean and healthy living behavior. The target of implementing the service is the community of Hamlet 3, Powelua Village, Donggala Regency, Central Sulawesi Province, which will be carried out in June 2024 for one day. The instrument used was a questionnaire, with a total sampling technique. Analysis of community service results, namely univariate analysis in the form of a description of knowledge and attitudes about 10 PHBS indicators. The results of community service showed that the level of community knowledge about PBHS before being given counseling was sufficient, and after being given PBHS counseling, knowledge increased where the majority had good knowledge. The implementation of PHBS needs to be improved so that individuals can help themselves with health problems or participate in creating a healthy society in their environmentKeywords: PHBS; Indicators; Powelua.
INTRODUCTION OF MEDICINE PREPARATIONS FOR HOUSEWIVES AT RW 003 TABARINGAN MAKASSAR
Authors: Sinala Santi , Teresia Rosmala Dewi Sisilia 
Published: February 2025

Pemilihan bentuk sediaan akan mempengaruhi tingkat kepatuhan pasien yang akan berdampak pada keberhasilan pengobatan. Pemberian obat secara oral adalah rute yang paling disukai oleh masyarakat karena menawarkan keuntungan seperti kemudahan penggunaannya, sangat fleksibel, dan dosis yang akurat.
Masalah yang dihadapi oleh beberapa masyarakat adalah rendahnya pengetahuan tentang penggunaan obat yang rasional, masyarakat kurang memahami obat apa saja yang boleh dibeli tanpa resep dan harus memakai resep dokter. Selain itu, masyarakat juga kurang memahami pengelolaan obat di rumah seperti cara penggunaan obat yang sesuai dengan bentuk sediaan obat dan cara membuang limbah obat.
Pada dasarnya obat adalah racun, sehingga penggunaan obat harus sesuai dengan aturan pakai. RW 003 Tabaringan belum mengetahui tentang penggunaan obat yang benar dan baik, penyimpanan dan pembuangan limbah obat. Terkadang mereka mengkonsumsi antibiotik tidak sesuai aturan, menyimpan obat tidak pada tempatnya, serta membuang obat tidak sesuai metode-metodenya. Pengetahuan dan pemahaman yang kurang tersebut dapat menyebabkan pengobatan yang tidak maksimal dan limbah obat dapat membahayakan lingkungan. Oleh karena itu, dilaksanakannya pengenalan sediaan obat yang merupakan bagian dari GeMa CerMat (Gerakan Masyarakat Cerdas Menggunakan Obat).
Di rumah, banyak ibu rumah tangga yang belum mengetahui bentuk sediaan obat yang sesuai dengan cara penggunaan dari bentuk sediaan obat, baik sesuai resep dokter dan obat-obatan yang biasa dibeli tampa resep dokter. Ada beberapa obat yang menurut pengetahuan ibu rumah tangga sebaiknya obat tablet dikunyah agar efek dari obat cepat memberikan terapi pada tubuh. Ibu rumah tangga juga mengaku sangat jarang membaca kemasan atau brosur obat, namun mereka cukup mengerti perihal obat yang kadaluarsa, tidak bisa dipakai, dan harus dibuang ke tempat sampah.
Terkait permasalahan tersebut, diputuskan untuk memberikan penyuluhan dalam bentuk pembelajaran aktif terkait penggunaan obat sesuai dengan bentuk sediaan obat. Metode Penyuluhan ini dilaksanakan secara tatap muka dengan metode ceramah serta penayangan video/gambar bentuk sediaan. Dengan melakukan penyuluhan ini ibu-ibu rumah tangga dapat mendapatkan informasi mengenai cara membedakan bentuk sedian obat serta cara pengunaan yang baik dan benar.
KROKOT (Portulaca oleracea) SEBAGAI BAHAN BAKU MAKANAN DAN MINUMAN SEHAT UNTUK PENGEMBANGAN EKONOMI IBU MAJELIS TAKLIM AL-IKHLAS MAKASSAR
Authors: Nur Azizah Rizqi , Kamri Andi Maulana , Awali Muh. Noer , Isma Aidil Febryan Arya 
Published: February 2025

Potensi pasar akan bahan baku dan produk yang memiliki daya saing menjadi sebuah komuditas yang kadang sulit dicara oleh masyarakat kalangan bawah. Tanaman krokot (Portulaca oleraceae) yang melimpah dan digunakan secara empiris sebagai obat tradisional untuk meningkatkan kekebalan tubuh, menurunkan lipid dan glukosa darah, bakteriostatik, antineoplastik dan fungsi anti depresan, penyakit kulit, dan antiinflamasi. Berdasarkan uraian analisis situasi yang telah dikemukakan, tim PKM memberikan solusi sebagai berupa penyuluhan dan pengenalan tanaman krokot serta potensinya untuk dijadikan peluang usaha dan pengenalan keamanan pangan sesuai Good Manufacturing Practice (GMP) dan pelatihan dan Pendampingan Produksi Krokotea (Teh krokot) dan Krokonies (Brownies Krokot). Krokot (Portulaca oleracea), yang sering dianggap sebagai tanaman liar, sebenarnya kaya akan nutrisi dan manfaat kesehatan, menjadikannya bahan yang ideal untuk produk teh herbal yang unik dan menyehatkan. Mengembangkan teh krokot sebagai produk UMKM dapat menjadi peluang usaha yang menjanjikan, terutama dengan meningkatnya minat masyarakat terhadap produk alami dan herbal. Brownies Krokot dan Teh Krokot dapat diproduksi secara mandiri oleh mitra sebagai makanan dan minuman sehat berbahan dasar herbal Krokot (Portulaca oliracea) dengan bimbingan dari tim Pengabdian Universitas Muslim Indonesia.