bluuebunny/crossref_metadata_2025_split huggingface dataset:
Działalność dydaktyczna i badawcza ks. dr. Józefa Glempa
Authors: Góralski Wojciech 
Published: April 2024

Ksiądz dr Józef Glemp, absolwent Wydziału Obojga Praw Papieskiego Uniwersytetu Laterańskiego w Rzymie, a także Studium Administracji Kościelnej przy Kongregacji Soboru oraz Studium Rotalnego, pełni od 1967 roku absorbujące funkcje w Sekretariacie Prymasa Polski. Rok później podjął również pracę dydaktyczną na Wydziale Prawa Kanonicznego Akademii Teologii Katolickiej w Warszawie, gdzie prowadził ćwiczenia z prawa rzymskiego oraz kanonicznego prawa małżeńskiego, które kontynuował do roku 1979, kiedy to został mianowany przez Jana Pawła II biskupem warmińskim.
Znaczącą pomocą dydaktyczną dla studentów był opracowany przez niego skrypt Lexiculum prawa rzymskiego (Warszawa 1974).Prowadził pracę badawczą, której owocem jest ponad 50 publikacji, które wzbogaciły piśmiennictwo kanonistyczne. Wśród tych tekstów dostrzec można następujące nurty tema- tyczne: Kościół lokalny i partykularny, małżeństwo, sądownictwo kościelne, historia prawa kanonicznego w Polsce, a w szczególności biografistyka. Prace te znamionuje oryginalność w ujęciu poruszanych zagadnień (w szczególności z zakresu prawa małżeńskiego), jasność wywodów oraz stosowanie właściwych metod.
„Nie będziesz miał bogów cudzych przede Mną” (Wj 20,3). Przesłanie moralne kardynała Stefana Wyszyńskiego, prymasa Polski
Authors: Dziuba Andrzej 
Published: April 2024

Pierwsze przykazanie Dekalogu odnosi się do prawdy samego Boga. Człowiek ze swej natury już od początku swego świadomego życia nosi w sobie potrzebę odnoszenia się do Boga. Jest uznawany pozytywnie za Boga Stwórcę. Kardynał Wyszyński zwraca uwagę, że trzeba od początku widzieć w Nim także Ojca w Chrystusie. W kontekście tej wielkości Boga pojawia się również, jak mówi opis biblijny, pragnienie przebóstwienia człowieka, aby człowiek chciał zastąpić Boga. Następnie dochodzi do tego deifikacji materii, która jest zaprzeczeniem przykazania: nie mieć innych bogów. Taki sposób myślenia prowadzi do zanegowania Boga i poważnego zachwiania zaufania do Niego. W tym kontekście pojawiają się różne formy ateizmu. Z kolei człowiek zaczyna budować inną koncepcję wolności i inaczej z niej korzystać. Życie człowieka według Dekalogu nie jest zadaniem łatwym. Niejednokrotnie człowiek musi przezwyciężyć różne pokusy, jakie oferuje pogański świat, wraz z różnymi przemianami. A jednak różne postawy wobec tego zjawiska mogą prowadzić do dojrzałości wiary.
Colorectal Cancer Stem Cell Biomarkers: Biological Traits and Prognostic
Insights
Authors: Soleimani Atena , Saeedi Nikoo , Al-Asady Abdulridha Mohammed , Nazari Elnaz , Hanaie Reyhane , Khazaei Majid , Ghorbani Elnaz , Akbarzade Hamed , Ryzhikov Mikhail , Avan Amir , Mehr Seyed Mahdi Hasanian 
Published: April 2024

Abstract:
Due to self-renewal, differentiation, and limitless proliferation properties, Cancer Stem Cells
(CSCs) increase the probability of tumor development. These cells are identified by using CSC markers,
which are highly expressed proteins on the cell surface of CSCs. Recently, the therapeutic application of CSCs
as novel biomarkers improved both the prognosis and diagnosis outcome of colorectal Cancer. In the present
review, we focused on a specific panel of colorectal CSC markers, including LGR5, ALDH, CD166, CD133,
and CD44, which offers a targeted and comprehensive analysis of their functions. The selection criteria for these
markersCancer were based on their established significance in Colorectal Cancer (CRC) pathogenesis and
clinical outcomes, providing novel insights into the CSC biology of CRC. Through this approach, we aim to elevate
understanding and stimulate further research for developing effective diagnostic and therapeutic strategies
in CRC.
Comprehensive Insights into Pathophysiology of Alzheimer's Disease:
Herbal Approaches for Mitigating Neurodegeneration
Authors: Sen Debasis , Rathee Sunny , Pandey Vishal , K. Jain Sanjay , K. Patil Umesh 
Published: April 2024

Abstract:
Alzheimer's disease [AD] is a progressive neurodegenerative disorder characterized by
cognitive decline, memory loss, and functional impairment. Despite extensive research, the exact
etiology remains elusive. This review explores the multifaceted pathophysiology of AD, focusing
on key hypotheses such as the cholinergic hypothesis, hyperphosphorylated Tau Protein and Amyloid
β hypothesis, oxidative stress hypothesis, and the metal ion hypothesis. Understanding these
mechanisms is crucial for developing effective therapeutic strategies. Current treatment options
for AD have limitations, prompting the exploration of alternative approaches, including herbal interventions.
Cholinesterase inhibitors, targeting the cholinergic hypothesis, have shown modest efficacy
in managing symptoms. Blocking Amyloid β [Aβ] and targeting hyperphosphorylated tau
protein are under investigation, with limited success in clinical trials. Oxidative stress, implicated
in AD pathology, has led to the investigation of antioxidants. Natural products, such as Punica
granatum Linn, Radix Scutellariae, and Curcuma longa have demonstrated antioxidant properties,
along with anti-inflammatory effects, offering potential neuroprotective benefits. Several herbal
extracts, including Ginkgo biloba, Bacopa monnieri, and Withania somnifera, have shown
promise in preclinical studies. Compounds like Huperzine A, Melatonin, and Bryostatin exhibit
neuroprotective effects through various mechanisms, including cholinergic modulation and anti-inflammatory
properties. However, the use of herbal drugs for AD management faces limitations, including
standardization issues, variable bioavailability, and potential interactions with conventional
medications. Additionally, the efficacy and safety of many herbal products remain to be established
through rigorous clinical trials. This review also highlights promising natural products currently
in clinical trials, such as Resveratrol and Homotaurine, and their potential impact on AD
progression. DHA, an omega-3 fatty acid, has shown cognitive benefits, while Nicotine is being
explored for its neuroprotective effects. In conclusion, a comprehensive understanding of the complex
pathophysiology of AD and the exploration of herbal interventions offer a holistic approach
to managing this devastating disease. Future research should address the limitations associated
with herbal drugs and further evaluate the efficacy of promising natural products in clinical settings.
An Overview of Recent Analytical Techniques for Air Quality Monitoring
and Assessment
Authors: Mohammed Sa’adatu Eri , Badamasi Hamza , Unimke Augustine A. , Durumin Iya Naseer Inuwa , Olubunmi Aderibigbe Deborah , Okoro Chinyere , Okezie Onyemaechi , Olaleye Abdul Ademola 
Published: April 2024

Abstract:
Access to clean air, a vital necessity for life, faces severe constraints globally due to industrialization and urbanization, leading to widespread air quality deterioration. To safeguard human
health and the environment from detrimental effects, the essential components of proper monitoring,
assessment, and management of air quality are paramount. Conventional air quality analytical techniques such as gas chromatography/ mass spectrometry, selected ion flow tube mass spectrometry,
thermal desorption/ gas chromatography, and mass spectrometry are widely used for air quality analysis. These methods, however, are laborious, necessitate sample preparation, require expansive and
hazardous reagents, and have a high cost of equipment and maintenance. As such, more rapid, sensitive, specific, cost-effective, portable, user-friendly, and environmentally friendly analytical tools are
required for efficient air quality monitoring and control. Over the years, various techniques have
emerged to address these challenges, including mobile sensors, microbial monitoring, the Internet of
Things (IoT), biomonitoring, and bio- and nanosensors in both indoor and outdoor settings. This
paper offers an overview of recent advancements in air quality monitoring and assessment methods.
The review encompasses sample preparations for air pollutants, data analysis methodologies, and
monitoring strategies. It also delves into the crucial role of microorganisms in air quality analysis.
Additionally, the paper explores the applications of the Internet of Things (IoT) and biosensors in air
quality monitoring and assessment, elucidating their roles in advancing these endeavors. The paper
concludes by presenting insightful perspectives on the current state of air quality monitoring techniques and outlining future directions for research and development in this critical field.
Primary Pulmonary Lymphoepithelioma-like Carcinoma: A Case Report Utilizing
Camrelizumab and Anlotinib for Prolonged Survival
Authors: Lei ShuangYi , Tian ShanShan , Lu SongMei , Qing Zhou , Long JianLin , Li LuChun , Yang Dan 
Published: April 2024

Background:
Primary Pulmonary Lymphoepithelioma-like Carcinoma (PPLELC) is a rare form of
cancer for which no standard treatment has been established to date. Patients with advanced-stage PPLELC generally
have a poor prognosis with overall survival of 22.7 months.

Case Presentation:
Here, we report a case of advanced primary pulmonary lymphoepithelioma-like carcinoma.
Initially, the patient underwent a first-line (GP) and a second-line (DP) of chemotherapy, which provided temporary
relief but resulted in varying degrees of myelosuppression. When the disease progressed again, we administered
a third-line treatment consisting of camrelizumab combined with anlotinib.

Result:
This resulted in a progression-free survival of over 26 months without significant toxic side effects.

Conclusion:
Our findings suggest that combining camrelizumab and anlotinib could lead to a long progressionfree
survival in patients with advanced PPLELC.
Lactic Acid Bacteria As Biological Control Agent For Controlling Aspergillus Growth and Aflatoxin Production: A Review
Authors: Ahuja Rubi , Khan Minhaj Ahmad 
Published: April 2024

:
Aspergillus sp., a ubiquitous filamentous fungus, poses significant challenges to the food industry
as a common spoilage and mycotoxin producing organism. The conventional use of chemical preservatives
to control Aspergillus contamination raises concerns about potential health risks and environmental impacts.
Therefore, alternative approaches, such as the utilization of natural biopreservatives, as inexpensive, safe,
and promising mycotoxin decontamination strategies are being explored. Lactic acid bacteria have gained
considerable attention as potential candidates due to their antimicrobial properties and long-standing safe use
in food fermentation. This review provides a thorough summary of the potential of lactic acid bacteria as
biopreservatives against Aspergillus sp. The inhibitory mechanisms of lactic acid bacteria against the proliferation
of Aspergillus and mycotoxin yield are explored, highlighting the role of organic acids, antimicrobial
peptides, and other bioactive compounds. The versatile application of lactic acid bacteria based natural preservatives
across a range of food matrices, storage conditions, etc. is also addressed. Further research is warranted
to optimize lactic acid bacteria strains, explore synergistic combinations, and investigate their efficacy
in real food systems. Implementing lactic acid bacteria based biopreservative strategies could significantly
enhance food safety and quality by reducing Aspergillus contamination and mycotoxin risks.
Análisis de la implementación de cárceles agrícolas de la Zona 8 del Ecuador, un aporte a la inlclusión y sostenibilidad
Authors: Sotomayor Peralta Melany , Tigrero Romero Andrea , Marriott Zurita Gustavo 
Published: April 2024

Los resultados que se exponen proceden de la investigación desarrollada con el objetivo de analizar la alternativa de implementación de cárceles agrícolas en atención a la rehabilitación social de los sancionados con pena privativa de libertad hasta cinco años en los establecimientos penitenciarios de la zona 8 de Ecuador. Asumido el enfoque cuantitativo con alcances descriptivo y explicativo, con el uso del método inductivo-deductivo y sistémico se establecieron las regularidades jurídicas. El estudio documental, la encuesta y la entrevista, con la aplicación de métodos matemáticos, posibilitó la corroboración sobre las insuficiencias de la rehabilitación en el sistema carcelario. Se obtuvieron criterios desfavorables de las condiciones de los establecimientos penitenciarios de la zona y de la atención por parte del Estado. La experiencia de los abogados participantes, confirma la importancia de actividades productivas para la rehabilitación y autovaloración del sancionado de hasta cinco años de privación de libertad con vistas a su reincorporación social y recomiendan la implementación de cárceles agrícolas para los sancionados por delitos de menor trascendencia, en cumplimiento de lo refrendado por la Constitución de la República, siendo esencial, la garantía presupuestaria; el mejoramiento de la seguridad carcelaria; y, la capacitación de los funcionarios del sistema.
A Random Forest Algorithm for Assessing Risk Factors Associated With Chronic Kidney Disease: Observational Study
Authors: Liu Pei , Liu Yijun , Liu Hao , Xiong Linping , Mei Changlin , Yuan Lei 
Published: April 2024

Background
The prevalence and mortality rate of chronic kidney disease (CKD) are increasing year by year, and it has become a global public health issue. The economic burden caused by CKD is increasing at a rate of 1% per year. CKD is highly prevalent and its treatment cost is high but unfortunately remains unknown. Therefore, early detection and intervention are vital means to mitigate the treatment burden on patients and decrease disease progression.

Objective
In this study, we investigated the advantages of using the random forest (RF) algorithm for assessing risk factors associated with CKD.

Methods
We included 40,686 people with complete screening records who underwent screening between January 1, 2015, and December 22, 2020, in Jing’an District, Shanghai, China. We grouped the participants into those with and those without CKD by staging based on the glomerular filtration rate staging and grouping based on albuminuria. Using a logistic regression model, we determined the relationship between CKD and risk factors. The RF machine learning algorithm was used to score the predictive variables and rank them based on their importance to construct a prediction model.

Results
The logistic regression model revealed that gender, older age, obesity, abnormal index estimated glomerular filtration rate, retirement status, and participation in urban employee medical insurance were significantly associated with the risk of CKD. On RF algorithm–based screening, the top 4 factors influencing CKD were age, albuminuria, working status, and urinary albumin-creatinine ratio. The RF model predicted an area under the receiver operating characteristic curve of 93.15%.

Conclusions
Our findings reveal that the RF algorithm has significant predictive value for assessing risk factors associated with CKD and allows the screening of individuals with risk factors. This has crucial implications for early intervention and prevention of CKD.
Assessing Differences in mHealth Usability and App Experiences Among Young African American Women: Secondary Analysis of a Randomized Controlled Trial
Authors: Opper Claudia A , Browne Felicia A , Howard Brittni N , Zule William A , Wechsberg Wendee M 
Published: April 2024

Background
In North Carolina, HIV continues to disproportionately affect young African American women. Although mobile health (mHealth) technology appears to be a tool capable of making public health information more accessible for key populations, previous technology use and social determinants may impact users’ mHealth experiences.

Objective
The objective of this study was to evaluate mHealth usability, assessing differences based on previous technology use and social determinants among a sample of African American women in emerging adulthood.

Methods
As part of a National Institute on Drug Abuse–funded randomized controlled trial with African American women (aged 18-25 years), counties were assigned to receive an evidence-based HIV risk reduction intervention through mHealth and participants were asked to complete usability surveys at 6- and 12-month follow-ups. Participants’ first survey responses were analyzed through 2-tailed t tests and linear regression models to examine associations with previous technology use and social determinants (P<.05).

Results
The mean System Usability Scale (SUS) score was 69.2 (SD 17.9; n=159), which was higher than the threshold of acceptability (68.0). Participants who had previously used a tablet indicated higher usability compared to participants without previous use (mean 72.9, SD 18.1 vs mean 57.6, SD 11.4; P<.001), and participants with previous smartphone use also reported higher usability compared to participants without previous use (mean 71.9, SD 18.3 vs mean 58.0, SD 10.7; P<.001). Differences in SUS scores were observed among those reporting homelessness (mean 58.3, SD 19.0 vs mean 70.8, SD 17.2; P=.01), unemployment (mean 65.9, SD 17.2 vs mean 71.6, SD 18.1; P=.04), or current school enrollment (mean 73.2, SD 18.5 vs mean 65.4, SD 16.5; P=.006). Statistically significant associations were not observed for food insecurity (mean 67.3, SD 18.6 vs mean 69.9, SD 17.7; P=.45).

Conclusions
Although above-average usability was observed overall, these findings demonstrate differences in mHealth usability based on past and current life experiences. As mHealth interventions become more prevalent, these findings may have important implications for ensuring that mHealth apps improve the reach of evidence-based interventions.

Trial Registration
ClinicalTrials.gov NCT02965014; https://clinicaltrials.gov/study/NCT02965014

International Registered Report Identifier (IRRID)
RR2-10.1186/s12889-018-5796-8
Utilization of Arbuscular Mycorrhizal Fungi and Bacillus velezensis Inoculation in Suppressing Twisted Disease of Shallot
Authors: Abdullah Jilan Tsani , Suryanti Suryanti , Joko Tri 
Published: April 2024

Twisted disease is one of the problems in shallot cultivation. The application of the biological agents Bacillus velezensis and Arbuscular Mycorrhizal Fungi is an alternative expected to overcome disease problems in shallot plantings. The purpose of this study was to determine the effect of the application of B. velezensis and Arbuscular Mycorrhizal Fungi on the growth and health of shallot. The research was conducted in Gotakan, Panjatan, Kulon Progo, and the Phytopathology Laboratory, Department of Plant Protection, Faculty of Agriculture, Universitas Gadjah Mada, Yogyakarta. Shallot treatments with the application of biological agents were carried out either individually by soaking the bulbs in B. velezensis suspension before planting, coating the bulbs using Arbuscular Mycorrhizal Fungus (Rhizophagus intraradices) with a carrier medium of kaolin flour before planting, and a combination of spraying the B. velezensis suspension on plants at two-week intervals during the growth period and coating the bulbs before planting with R. intraradices. The results of the study showed that the shallot-applied single application of B. velezensis reduced the intensity and incidence of twisted disease by 2.51% and 37.6%, respectively. The combination treatment of B. velezensis and R. intraradices was able to increase the resistance of bulbs to postharvest pathogen Fusarium solani infection, with infected bulbs and areas of 0.70% and 0.71%, respectively.
El diagnóstico como estrategia para conocer la presencia de la discapacidad en la Escuela Nacional de Trabajo Social
Authors: Lázaro Jiménez Elía , Silva Montealegre Tomas 
Published: April 2024

Referirse a la discapacidad conlleva a conocer el modelo social de la discapacidad, modelo que permite describir la dinámica de la discapacidad desde una mirada social y no médica, como se solía hacer hasta los inicios del siglo XX, el cual ubica que las causas de la discapacidad no son religiosas ni científicas, sino sociales; pues no son las limitaciones individuales las raíces del problema, sino son las limitaciones de la propia sociedad para prestar servicios apropiados y, así, asegurar que las necesidades de las personas con discapacidad sean tomadas en cuenta dentro de la organización social. Ante ello, el escenario escolar es un ópico que resulta ser importante en el tema de la discapacidad, pues este espacio además de consolidar los procesos de enseñanza-aprendizaje,consolida las estructuras de las relaciones sociales de la persona; así escuela-discapacidad se torna en una dicotomía donde se referencia el proceso socioeducativo de la persona con discapacidad. Es por ello que el presente artículo muestra la estrategia que siguió el Comité de atención a las personas con discapacidad de la Universidad Nacional Autónoma de México, CAD-UNAM, en la Escuela Nacional de Trabajo Social, permitiendo conocer por primera vez la presencia de las personas con discapacidad, además de dar las bases para la construcción de una Escuela y Universidad Inclusiva. Estrategia que se baso en la construcción de un diagnóstico, el cual permite vislumbrar la naturaleza y magnitud de las necesidades, en este caso permitió debelar la realidad de la presenciade las personas con discapacidad en la Escuela Nacional de Trabajo Social. De esta forma para abordar la discapacidad, así como a las personas con discapacidad dentro de la escuela, resulta trascendental involucrarse en undiálogo dinámico que permita, responder: ¿Qué es la discapacidad? ¿Quiénes son las personas con discapacidad?¿Cómo apoyo a las personas con discapacidad? ¿Pueden las personas con discapacidad trabajar y/o estudiar en la universidad?
El territorio como unidad de análisis en la investigación social
Authors: Calzada Lemus Francisco , Osorio Orozco Marco Antonio 
Published: April 2024

Para abordar el concepto de territorio desde la disciplina de Trabajo Social, es necesario comprender cuáles son los elementos sociales que lo componen, considerando que se puede interpretar a partir del momento histórico desde donde se construye, la mirada teórica que lo explica y la intención metodológica que invita al investigar su integración. Estos elementos se formulan como una síntesis que centran el territorio como una unidad de análisis transdiciplinario, en la perspectiva de generar mayor conocimiento en la investigación social para orientar la intervención en los escenarios socialmente complejos.
¿Seguridad pública sin proceso democrático de pacificación? Siete premisas fenomenológicas sobre México
Authors: De la Cruz Lugardo Pedro Isnardo 
Published: April 2024

La profundización del esquema de militarización, la ausencia de control social en términos de gobernabilidad eficaz desde las instituciones y poderes del Estado (tanto en lo administrativo, como policial y militar), así como la escalada del narcotráfico como principal eje de la economía de diversas regiones del país, anulan el sentido de libertad y la existencia de un Estado de derecho, ante la amenaza permanente de muerte o exposición al azar de la violencia extrema, a modo de una administración desgastada y cada vez menos creíble desde las instituciones del Estado, de la sociedad actual del riesgo. Es necesario repensar la estrategia nacional en clave de pacificación justa y nuevos procesos de diálogo social y comunitario.