bluuebunny/crossref_metadata_2025_split huggingface dataset:
Occupying Shops to Defend Spaces of Livelihoods: From Tenant Shopkeepers’ Fragmentation to Collective Consciousness in Urban Korea
Authors: Lee Yewon Andrea 
Published: February 2024

Abstract
When commercial real estate becomes a highly coveted investment commodity, tensions intensify between those whose interest lies in extracting maximum profits from their properties and those who utilize the very same spaces for making a livelihood. Through ethnographic research with a tenant shopkeepers’ social movement organization (SMO) in Korea, I analyze the new collective consciousness forming among tenant shopkeepers who are defending their livelihoods against their landlords’ rapacious use of rent hikes and evictions to fully realize the speculative potential of their properties. Examining how the SMO brings together geographically scattered tenant shopkeepers based primarily in the larger metropolitan area of Seoul, I ask, more broadly: How can the self-employed facing precaritization overcome their fragmentation and generate a new collective consciousness based on a politics of solidarity? Drawing from my case study of tenant shopkeepers and the literature on livelihood struggles elsewhere around the globe, I identify the practice of occupying livelihood spaces as playing a pivotal role in the development of a sense of collective among those previously atomized in their struggles. I advance existing scholarship by scrutinizing both the challenges and the transformative potential of the solidarity cultivated through the occupy sites in bridging divergent interests, cultural sensibilities, and political beliefs of the previously unorganized.
In silico soil degradation and ecotoxicity analysis of veterinary pharmaceuticals on terrestrial species: first report
Authors: Banjare Purusottam , Singh Rekha , Pandey Nilesh Kumar , Matore Balaji Wamanrao , Murmu Anjali , Singh Jagadish , Roy Partha Pratim 
Published: February 2024

Abstract
With the aim of persistence property analysis and ecotoxicological impact of veterinary pharmaceuticals on different terrestrial species, different classes of veterinary pharmaceuticals (n = 37) with soil degradation property (DT50) were gathered and subjected to QSAR and q-RASAR model development. The models were developed from 2D descriptors under organization for economic cooperation and development guidelines with the application of multiple linear regressions along with genetic algorithm. All developed QSAR and q-RASAR were statistically significant (Internal = R2adj: 0.721–0.861, Q2LOO: 0.609–0.757, and external = Q2Fn = 0.597–0.933, MAEext = 0.174–0.260). Further, the leverage approach of applicability domain assured the model’s reliability. The veterinary pharmaceuticals with no experimental values were classified based on their persistence level. Further, the terrestrial toxicity analysis of persistent veterinary pharmaceuticals was done using toxicity prediction by computer assisted technology and in-house built quantitative structure toxicity relationship models to prioritize the toxic and persistent veterinary pharmaceuticals. This study will be helpful in estimation of persistence and toxicity of existing and upcoming veterinary pharmaceuticals.
Is There a Bright Side to the China Syndrome? Rising Export Opportunities and Life Satisfaction in China
Authors: Crozet Matthieu , Hering Laura , Poncet Sandra 
Published: February 2024

Abstract
Export growth affects individuals through numerous and contradictory channels. In China, the development of exports has promoted economic development and income growth, but it has also disrupted social structures and work environments. This paper explores the overall effect of exports on perceived well-being by combining responses from a large longitudinal survey covering over 45,000 Chinese with a shift-share measure of local export opportunities. Results show that individuals’ perceived life satisfaction increases significantly in prefectures that benefited from greater export opportunities, despite a negative effect on self-reported health. The positive well-being gains go beyond a simple income effect. These non-monetary gains are related to the individuals’ professional life: export-related well-being gains are stronger for working-age individuals (especially men and low-skilled workers), are largest for workers in the manufacturing sector (which produces the vast majority of China’s exports), and are found when the satisfaction indicator focuses on work but not on other aspects of daily life.
Timing of Coronavirus Disease 2019 (COVID-19) Vaccination and Effects on Menstrual Cycle Changes
Authors: Edelman Alison , Boniface Emily R. , Male Victoria , Cameron Sharon , Benhar Eleonora , Han Leo , Matteson Kristen A. , van Lamsweerde Agathe , Pearson Jack T. , Darney Blair G. 
Published: February 2024

OBJECTIVE:
To assess whether menstrual cycle timing (follicular or luteal phase) of coronavirus disease 2019 (COVID-19) vaccine administration is associated with cycle length changes.

METHODS:
We used prospectively collected (2021–2022) menstrual cycle tracking data from 19,497 reproductive-aged users of the application “Natural Cycles.” We identified whether vaccine was delivered in the follicular or luteal phase and also included an unvaccinated control group. Our primary outcome was the adjusted within-individual change in cycle length (in days) from the average of the three menstrual cycles before the first vaccination cycle (individuals in the unvaccinated control group were assigned a notional vaccine date). We also assessed cycle length changes in the second vaccination cycle and whether a clinically significant change in cycle length (8 days or more) occurred in either cycle.

RESULTS:
Most individuals were younger than age 35 years (80.1%) and from North America (28.6%), continental Europe (33.5%), or the United Kingdom (31.7%). In the vaccinated group, the majority received an mRNA vaccine (63.8% of the full sample). Individuals vaccinated in the follicular phase experienced an average 1-day longer adjusted cycle length with a first or second dose of COVID-19 vaccine compared with their prevaccination average (first dose: 1.00 day [98.75% CI, 0.88–1.13], second dose: 1.11 days [98.75% CI, 0.93–1.29]); those vaccinated in the luteal phase and those in the unvaccinated control group experienced no change in cycle length (respectively, first dose: −0.09 days [98.75% CI, −0.26 to 0.07], second dose: 0.06 days [98.75% CI, −0.16 to 0.29], unvaccinated notional first dose: 0.08 days [98.75% CI, −0.10 to 0.27], second dose: 0.17 days [98.75% CI, −0.04 to 0.38]). Those vaccinated during the follicular phase were also more likely to experience a clinically significant change in cycle length (8 days or more; first dose: 6.8%) than those vaccinated in the luteal phase or unvaccinated (3.3% and 5.0%, respectively; P<.001).

CONCLUSION:
COVID-19 vaccine–related cycle length increases are associated with receipt of vaccination in the first half of the menstrual cycle (follicular phase).
Autoantibodies in rheumatoid arthritis – rheumatoid factor, anticitrullinated protein antibodies and beyond
Authors: Steiner Günter , Toes René E.M. 
Published: February 2024

Purpose of review
RA is characterized by the presence of autoantibodies among which rheumatoid factors (RFs) and antimodified protein antibodies (AMPA) are serological hallmarks of the disease. In recent years, several novel insights into the biology, immunogenetics and clinical relevance of these autoantibodies have been obtained, which deserve to be discussed in more detail.

Recent findings
RFs from RA patients seem to target distinct epitopes which appear to be quite specific for RA. Determination of immunoglobulin A (IgA) isotypes of RF and anticitrullinated protein antibodies (ACPA) may provide prognostic information because their presence is associated with reduced therapeutic responses to TNF inhibitors. Furthermore, IgA levels are increased in RA patients and IgA immune complexes are more potent than immunoglobulin G (IgG) complexes in inducing NET formation. Concerning AMPAs, investigations on variable domain glycosylation (VDG) revealed effects on antigen binding and activation of autoreactive B cells. Studies on pathogenetic involvement of ACPA suggest Janus-faced roles: on the one hand, ACPA may be involved in joint destruction and pain perception while on the other hand protective anti-inflammatory effects may be attributed to a subset of ACPAs.

Summary
The autoimmune response in RA is extremely complex and still far from being fully understood. Antibodies are not only valuable diagnostic biomarkers but also seem to play pivotal roles in the pathophysiology of RA.
Late-week Multilevel Anterior Cervical Discectomy and Fusion Associated With Increased Length of Stay
Authors: Miller Evan M. , Polascik Bryce W. , Kitchen Spencer T. , Wahbeh Elias E. , Abouhaif Taylor M. , Contillo Nicholas J. , Elashker Adrianna L. , Hsia Michelle W. , Marsh Kathleen A. , Thometz Kyler J. , Yin Timothy C. , O’Gara Tadhg J. 
Published: February 2024

Study Design:
Retrospective analysis of clinical data from a single institution.

Objective:
To assess the day of surgery during the week as a possible predictor of length of stay (LOS) following anterior cervical discectomy and fusion (ACDF).

Summary of Background Data:
Surgeries later in the week may result in longer LOS and higher costs for joint arthroplasty, yet this is unclear following spine surgery. Procedures performed later in the week may lead to weekend admissions when there are limited services that may contribute to an extended LOS. We attempt to identify associations between day of surgery and LOS, readmission, and complications following single- and multilevel ACDF.

Materials and Methods:
Patients at a single institution undergoing ACDF by 7 primary surgeons in both orthopedic and neurosurgery spine departments between 2015 and 2019 were retrospectively reviewed. Patients were stratified by surgery day at either the beginning (Monday/Tuesday) or end (Thursday/Friday) of the week and by single- or multilevel ACDF. Surgery for trauma, infections, adjacent level disease, or revision were excluded. Patient demographics, Charlson Comorbidity Index (CCI), LOS, postoperative complications, and readmission rates were assessed.

Results:
Six hundred fifty-two patients underwent ACDF. For single-level ACDF, 222 were reviewed, with 112 having surgery at the beginning and 110 at the end of the week. For multilevel ACDF, 431 were reviewed, with 192 having surgery at the beginning and 239 at the end of the week. No differences in pre- or postoperative variables were determined for single-level ACDF. Despite no differences in pre-operative variables, CCI, operative duration, or number of levels, late-week multilevel ACDF had longer average LOS (2.8±3.0 days) compared to early-week surgery (2.0±2.0 days) (P=0.018).

Conclusions:
Late-week multilevel ACDF was associated with an increased LOS, as it may prove beneficial to surgical planning. This conflicts with previous reports that day of week was not associated with LOS following ACDF.

Level of Evidence:
III
Hemorrhoidectomy: Does Age Make a Difference?
Authors: Capece Steven J. , Browning Charles J. , Barros de Sousa Cesar A. , Shaak Kyle , Yoon Justin Y. , Sangster William 
Published: February 2024

BACKGROUND:
Grade II and III hemorrhoids often require a multimodal approach that may ultimately culminate to surgical resection. Age and overall medical conditioning around the time of diagnosis can often impact the decision.

OBJECTIVE:
The objective of this study was to evaluate patients with a diagnosis of symptomatic grade II or grade III hemorrhoids and determine progression to hemorrhoidectomy based on age and the time interval between diagnosis and surgical intervention.

DESIGN:
A retrospective cohort study.

SETTINGS:
Group practice at a single institution

PATIENTS:
Patients age 18-75 with grade II or grade III internal hemorrhoids between 2015 and 2020 were included. Patients with thrombosed hemorrhoids or surgical contraindications to hemorrhoidectomy were excluded. A total of 961 patients met inclusion criteria for Grade II (n = 442) and III (n = 519) hemorrhoids

INTERVENTION:
Treatments included hemorrhoidectomy, in-office procedures, and/or medical management.

MAIN OUTCOME MEASURES:
Baseline demographics, treatment choices and time to hemorrhoidectomy (if applicable) were stratified and analyzed based on hemorrhoid grade (grade II and III) and age groupings that were pre-determined by the authors (18-30, 31-50, and 51-75).

RESULTS:
Patients with Grade III vs Grade II hemorrhoids were more likely to choose hemorrhoidectomy as the initial treatment management (27.6% vs 4.1%). Patients in age groups 18-30 and 30-50 were more likely to choose hemorrhoidectomy as the initial treatment management compared to ages 51-75 years old (23.5% and 22% vs 12.8%). In patients who were initially treated with medical management or office-based procedures and then progressed to hemorrhoidectomy, no significant differences in length of time to hemorrhoidectomy were noted based on hemorrhoid grade or age.

LIMITATIONS:
Data only looks at age groups and their treatment selection. Personal biases of surgeon and patient may alter results.

CONCLUSION:
Our study shows that the younger population tend to seek hemorrhoidectomy first over the older population. See Video Abstract.
Clinical Utility of Laser Speckle Contrast Imaging and Real-Time Quantification of Bowel Perfusion in Minimally Invasive Left-Sided Colorectal Resections
Authors: Skinner Garrett C. , Liu Yao Z. , Harzman Alan E , Husain Syed G. , Gasior Alessandra C , Cunningham Lisa A. , Traugott Amber L. , McCulloh Christopher J. , Kalady Matthew F. , Kim Peter C. , Huang Emily S. 
Published: February 2024

BACKGROUND:
Left-sided colorectal surgery demonstrates high anastomotic leak rates, with tissue ischemia thought to influence outcomes. Indocyanine green is commonly used for perfusion assessment, but evidence remains mixed for whether it reduces colorectal anastomotic leaks. Laser speckle contrast imaging provides dye-free perfusion assessment in real-time through perfusion heatmaps and quantification.

OBJECTIVE:
This study investigates the efficacy of advanced visualization (indocyanine green versus laser speckle contrast imaging) perfusion assessment and utility of laser speckle perfusion quantification in determining ischemic margins.

DESIGN:
Prospective intervention group using advanced visualization with case-matched, retrospective control group.

SETTINGS:
Single academic medical center.

PATIENTS:
Forty adult patients undergoing elective, minimally invasive, left-sided colorectal surgery.

INTERVENTIONS:
Intraoperative perfusion assessment using white-light imaging and advanced visualization at three time points: T1 – proximal colon after devascularization, before transection; T2 – proximal/distal colon before anastomosis; and T3 – completed anastomosis.

MAIN OUTCOME MEASURES:
Intraoperative indication of ischemic line of demarcation before resection under each visualization method, surgical decision change using advanced visualization, post-hoc laser speckle perfusion quantification of colorectal tissue, and 30-day postoperative outcomes.

RESULTS:
Advanced visualization changed surgical decision making in 17.5% of cases. For cases in which surgeons changed a decision, the average discordance between line of demarcation in white-light imaging and advanced visualization was 3.7 cm, compared to 0.41 cm (p = 0.01) for cases without decision changes. There was no statistical difference between line of ischemic demarcation using laser speckle versus indocyanine green (p = 0.16). Laser speckle quantified lower perfusion values for tissues beyond the line of ischemic demarcation while suggesting an additional 1 cm of perfused tissue beyond this line. One (2.5%) anastomotic leak occurred in the intervention group.

LIMITATIONS:
This study was not powered to detect differences in anastomotic leak rates.

CONCLUSIONS:
Advanced visualization using laser speckle and indocyanine green provides valuable perfusion information that impacts surgical decision-making in minimally invasive left-sided colorectal surgeries. See Video Abstract.
Socioeconomic Disparities in Anal Cancer: Effect on Treatment Delay and Survival
Authors: Nepal Pramod , Zafar Muhammad , Liu Li C , Xu Ziqiao , Abdulhai Mohamad A. , Perez-Tamayo Alejandra M , Chaudhry Vivek , Mellgren Anders F , Gantt Gerald 
Published: February 2024

BACKGROUND:
Socioeconomic inequities have implications in access to health care and may be associated with disparities in treatment and survival.

OBJECTIVE:
To investigate the impact of socioeconomic inequities on time to treatment and survival of anal squamous cell carcinoma.

DESIGN:
This is a retrospective study using a nationwide dataset.

SETTINGS:
The patients were selected from National Cancer Database enrolled from 2004 to 2016.

PATIENTS:
We identified patient with stage I-III squamous cell carcinoma of anus who were treated with chemoradiation.

MAIN OUTCOMES MEASURES:
Socioeconomic factors, including race, insurance status, median household income, and percentage of no high school degrees were included. The association of these factors with treatment delay and overall survival were investigated.

RESULTS:
A total of 24,143 patients who underwent treatment for Grade I-III squamous cell carcinoma of anus were identified. Median age was 60 years and 70% were female. The median time to initiation of treatment was 33 days. Patients from zip codes with lower median income, higher percentage of no high school degree, and patients with other government insurance followed by Medicaid insurance had treatment initiated after 60 days from diagnosis. Kaplan-Meier survival analysis showed that the late treatment group had worse overall survival compared to early treatment group (98 vs 125 months; p < 0.001).

LIMITATIONS:
No detailed information about chemoradiotherapy regimen, completion of treatment, recurrence, disease free survival and individual level socioeconomic condition and risk factors.

CONCLUSION:
Patients from communities with lower median income, level of education, and enrolled in public insurance had longer time to treatment. Lower socioeconomic status was also associated with poorer overall survival. These results warrant further analysis and measures to improve access to care to address this disparity. See Video Abstract.
Alveolar Oral Layer Repair by Periosteal Grafts versus Maxillary Flaps and Gingivoperiosteoplasty: Techniques and Follow-up to Adolescence
Authors: El Danaf Ahmed A. , Al-Ahmady Hatem H. , Eldanaf Heba A. , Soliman Helmy A. , Elhelw Moustafa H. , Khalil Maurice F. , Rizk Ibrahim A. , Donia Mohamed S. 
Published: February 2024

Background:
Alveolar periosteoplasty during primary repair of cleft lip is still a topic of debate due to the fear exacerbating maxillary retrusion. The authors present their experience with early closure of alveolar clefts. The study aims to analyze gingivoperiosteoplasty (GPP) by comparing the use of locoregional flaps versus distant grafts for reconstruction of the lower layer of the primary palate cleft.

Methods:
Seventeen infants underwent 22 alveolar cleft repairs. After nasal floor repair by nasal mucoperiosteum, the oral layer was repaired by maxillary or gingival periosteal flaps in seven patients with alveolar clefts less than or equal to 6 mm wide, and tibial or pericranial periosteal grafts in 10 patients with wider clefts. At teenage years, crossbites in three flap-GPP and three graft-GPP patients were compared with nine older adolescents without primary GPP.

Results:
Alveolar clefts were perfectly sealed. Radiographs during the early 3 postoperative years showed new bone formation more posteriorly extended in patients who underwent graft-GPP. Teeth eruption and alveolar rigidity at the mixed dentition age eliminated the need for secondary bone grafting. The anterior crossbites in adolescent patients ranged between −2 and −14 mm; crossing was relatively smaller in patients with a younger age and without cleft palate. The mean crossbite was 7.2 mm in the six teenagers and 9.6 mm in the control cases.

Conclusions:
Graft-GPP may be a good alternative to flap-GPP, particularly for wide alveolar cleft repair. Maxillary retrusion is aggravated in patients with cleft palate and older age at assessment. GPP may not increase crossbite.
Work Characteristics, Workplace Support, and Mental Ill-Health in a Canadian Cohort of Healthcare Workers During the COVID-19 Pandemic
Authors: Cherry Nicola , Adisesh Anil , Burstyn Igor , Durand-Moreau Quentin , Galarneau Jean-Michel , Labrèche France , Ruzycki Shannon , Zadunayski Tanis 
Published: February 2024

Objective
The aim of the study was to identify determinants of mental health in healthcare workers (HCW) during the COVID-19 pandemic.

Methods
A cohort of Canadian HCW completed four questionnaires giving details of work with patients, ratings of workplace supports, a mental health questionnaire, and substance use. Principal components were extracted from 23 rating scales. Risk factors were examined by Poisson regression.

Results
A total of 4854 (97.8%) of 4964 participants completed ratings and mental health questionnaires. Healthcare workers working with patients with COVID-19 had high anxiety and depression scores. One of three extracted components, ‘poor support,’ was related to work with infected patients and to anxiety, depression, and substance use. Availability of online support was associated with feelings of better support and less mental ill-health.

Conclusions
Work with infected patients and perceived poor workplace support were related to anxiety and depression during the pandemic.
Work and Lifestyle Factors Influencing Job Satisfaction of Japanese Civil Servants
Authors: Nishioka Ryuichiro , Tatsuse Takashi , Sekine Michikazu , Yamada Masaaki 
Published: February 2024

Objective
Although work, family, and lifestyle factors were associated with job satisfaction, prospective studies are lacking. This longitudinal study clarified the predisposing factors for job satisfaction.

Methods
Datasets were obtained from the Japanese Civil Servants Study and included 1429 participants. We assessed the relationship between job satisfaction and specific work and lifestyle factors. Logistic regression analyses evaluated the association between deteriorating job satisfaction and poor work and lifestyle factors at baseline and changes in these factors at follow-up.

Results
Poor sleep quality and limited job control at baseline were associated with deterioration in job satisfaction. Furthermore, deterioration in job control and work-to-family conflict at follow-up was associated with job dissatisfaction.

Conclusion
Work and lifestyle characteristics were associated with job dissatisfaction. Employees with limited job control and high work-to-family conflict at baseline were more likely to develop job dissatisfaction.