bluuebunny/crossref_metadata_2025_split huggingface dataset:
Study on transformations in land use in the functional context of extensive city ventilation routes using the example of Bródnowski Ventilation Corridor in Warsaw, Poland
Authors: Podawca Konrad , Pawłat-Zawrzykraj Agata , Karsznia Krzysztof 
Published: March 2024

Abstract
Ventilation corridors are critical for regulating the appropriate flow of urban air streams. Details on how they function, especially in a specific location, can be found in local eco-physiographic studies. Such analyses are designed during conceptual work on the conditions and directions of the development of a studied area. Such documentation includes advanced research on the impact of natural conditions on the area's growth and evolution. In Warsaw, Poland, such a study makes it possible to define various natural areas that are essential for the appropriate functioning of the city and increase its inhabitants’ well-being. This provides an initial basis for further analysis and motivates researchers to investigate the distribution of natural sites. It inspired the authors to assess the land-use structure in the context of the location of ventilation corridors. Thus, land use and land cover (LULC) modifications were examined in the context of their tendency to aid in the ventilation of the city. The object of the study is the Bródnowski Ventilation Corridor (BVC) – one of several designated for Warsaw in the spatial planning concepts of the 1980s and 1990s. In the research encompassing the years 1982–2020, the authors analysed the land use and roughness determined by the development characteristics and vegetation cover. References were made to current and archival planning documents, aerial photographs, satellite images, and the Topographic Objects Database BDOT10k. The research was prompted by the municipality's intention to urbanize the study area, which will undoubtedly eliminate the ventilation function of the southern part of the corridor and significantly reduce its remaining territory. Analysis of changes in the land cover of the south part of the corridor confirms its marginal importance for the city's ventilation. In this area, ongoing modifications proceed slowly, and urbanization – mainly low-rise and less intensive buildings – is limited. This zone has largely retained and is likely to maintain its favourable features from the point of view of ventilation and air regeneration.
Environmental and Human Impact on Gully Erosion Recorded in Fan Sediments: A Case Study of the Vilnius area, Lithuania
Authors: Smolska Ewa , Szwarczewski Piotr , Česnulevičius Algimantas , Mažeika Jonas 
Published: March 2024

Abstract
Geomorphological and sedimentological research carried out in the vicinity of Vilnius (SW Lithuania) aimed to determine the age and stages of development of gullies in relation to climatic conditions and human activity. Two gullies located on the northern slope of the Vilnia river valley were examined in detail. The sedimentological features of the sediments which form fans at the mouths of the gullies were analysed. Three main lithological units were distinguished. On the basis of radiocarbon datings, the beginning of gully erosion was determined to be in the Middle Ages. This process began with intensive settlement in this area. Further stages of a cutting which were distinguished include early modern times and the period from the seventeenth century to the present day.
La delincuencia en México y la cohesión social. Un modelo econométrico de predicción
Authors: Guerrero Escamilla Juan Bacilio 
Published: March 2024

Uno de los daños más importantes y de gran impacto al deterioro de la sociedad, es el delito. Todas las sociedades lo tienen y son parte de su vida, de sus relaciones cotidianas, de sus instituciones, de su reglamentación y le dedican parte de sus recursos. Todas las sociedades mantienen una gran preocupación sobre el comportamiento de este fenómeno; lo analizan y lo estudian tratando de comprender cuáles son sus formas, tamaños, estadísticas, causas y funcionamiento, pero sobre todo sus límites. Esta preocupación tiene sentido en tanto los límites definen las fronteras de la descomposición social, del deterioro del tejido social, de la decadencia de sus instituciones, de las prácticas de hacer efectivo el sistema de procuración de justicia, del sistema de leyes y la regulación de las formas de convivencia de los Estados modernos.
INVESTIGATION OF DOSIMETRIC PROPERTIES OF TABLE SUGAR IRRADIATED WITH GAMMA RAYS USING EPR TECHNIQUE
Authors: Özmen Gül Bayramiye , Şahiner Eren 
Published: March 2024

In our study, it was observed that the EPR signals of table sugar irradiated with gamma rays at 3 kGy, 5 kGy, 10 kGy increased in proportion to the increasing dose. The fading in the signals was investigated by taking into account the peak-to-peak heights (Ipp) in the EPR spectra of table sugar. The stability of radicals was monitored by performing EPR measurements on sugar samples irradiated with high doses of gamma rays (Co-60) on 29.06.2020, 23.03.2021, 28.06.2021, 05.08.2021. Suitability evaluation was made with Z score, which is a statistical test to determine fading. It was observed that there was almost no loss in the EPR signals of sugar for 14 months.
Also table sugar; Similarities have been shown by comparing the EPR spectra of the fruits used in the TS EN 13708 Foodstuffs - Standard for determining whether foodstuffs containing crystal sugars are irradiated by ESR spectroscopy. Thanks to these similarities, it has been suggested that fruits can also be used as dosimeters, depending on the sugar they contain.
Monitoring Food Affordability: Reliability and Validity of an Online Nutritious Food Basket
Authors: Boyar Liza , Lakhani Ellis , Ho Ivan , King Bridget , Kennedy Lauren , Ellen Prange Mary , Harrington Daniel , Prowse Rachel 
Published: March 2024

Purpose: This study aimed to assess the reliability and validity of an online approach to monitoring food affordability in Ontario using the updated Ontario Nutritious Food Basket (ONFB). Methods: The ONFB was priced online in 12 large multi-chain grocery stores to test intra-/inter-rater reliability using percent agreement and intra-class correlations (ICCs). Then, the ONFB was priced in-store and online in 28 stores to estimate food price differences using paired t-tests and Pearson’s correlation for all (n =1708) and matched items (same product/brand and purchase unit) (n = 1134). Results: Intra-/inter-rater agreement was high (95.4%/81.6%; ICC = 0.972, F = 69.9, p < 0.001). On average, in-store prices were less than $0.02 lower than online prices. There were no significant differences between mean in-store and online prices for all items (t = 0.504 p = 0.614). The mean price was almost perfectly correlated between in-store and online (fully matched: R = 0.993 p < 0.001; all items: R = 0.967 p < 0.001). Online monthly ONFB estimates for a family of four were strongly correlated (R = 0.937 p < 0.001) with estimates calculated using in-store data. Conclusions: Online pricing is a reliable and valid approach to food costing in Ontario that contributes to modernizing the monitoring of food affordability in Canada and abroad.
Correlation Between HbA1c and Body Mass Index Among Patients with High Lipid Profile Attending Johns Hopkins Aramco Healthcare Hospital in Saudi Arabia
Authors: Kheir Omer , Dossary Sheikha , Dhalaan Mohammad , AlHajri Salman , Aljeshi Ali , Wali Dawoud Raseel , Ghamdi Mohammad 
Published: March 2024

BACKGROUND AND OBJECTIVES: Dyslipidemia is a modifiable risk factor for cardiovascular diseases, diabetes, and stroke. The primary objective of this study was to examine the relationship between HbA1C and body mass index (BMI) among patients with high lipid profiles.

METHODS: This retrospective, hospital-based study was conducted at Johns Hopkins Aramco Healthcare Facilities. Data were extracted from medical health records and included demographics, lipid profiles, and HBA1c measurements. The study included 2368 non-diabetic participants, and DATAtab was used to analyze the data.

RESULTS: The participants were 57.05% male and 78.42% Saudi. The mean age was 41.48±12.1 years, and the mean body mass index (BMI) was 28.44±5.53. There was a statistically significant relationship between the use of lipid lowering medicine and HbA1c (P<0.001). There was a very weak positive but statistically significant relationship between HbA1c and BMI (r = 0.18, P<0.001). HbA1c and systolic blood pressure appeared to have a statistically significant positive association (r = 0.16, P< 0.001). There was no correlation between HbA1c and low-density lipoprotein cholesterol (LDL-C), total cholesterol (TC), or diastolic blood pressure. There was an inverse correlation between HbA1c and high-density lipoprotein cholesterol (HDL-C) (r = -0.11, P< 0.001). Regression was performed using a linear multivariable analysis with HbA1c as the dependent variable, and age (B 0.192, P<0.001), BMI (B 0.119, P<0.001), HDL (B -0.058, P<0.005), triglyceride (B 0.093, P<0.001), lipid-lowering medication (B 0.104, P<0.001), systolic BP (B 0.060, P< 0.003) as independent variables.

CONCLUSION: The results indicated that HbA1c is linked to BMI, age, systolic blood pressure, triglycerides, and HDL-C levels. There was no correlation between HbA1c and LDL-C, TC, and diastolic blood pressure.
The distribution of Baitul Mal aid fund for joint bussiness group program : is it effective?
Authors: Desi Tamida  , Nanda Nanda Safarida , Muhammad Dayyan  
Published: March 2024

Objective – This study aims to analyze the level of effectiveness, supporting and inhibiting factors as well as the impact of the distribution of aid funds by Baitul Mal to Joint Business Groups in Peureulak District, East Aceh.
Method – This research collects primary data with interviewing the key informan from Baitul Mal East aceh and 5 beneficieries from each Joint Business Group Program (KUBE).
Findings – The results of this study indicate that The level of effectiveness of the distribution of aid funds by East Aceh Baitul Mal to the Joint Business Group in Peureulak is considered to be still not optimal. This is assessed based on 4 main indicators, namely input, process, productivity, job satisfaction. Besides that, in its implementation, there are several supporting and inhibiting factors in efforts to distribute Joint Business Group (KUBE) assistance funds. The supporting factors include the availability of the latest information that is easily accessible to muzakki and mustahik, the presence of accompanying personnel and also the availability of a budget. Meanwhile, the inhibiting factors include inadequate facilities and infrastructure, still a lack of manpower, remote and difficult to reach locations and delays in sending files. Meanwhile, in terms of the impact of the distribution of aid funds, it is considered to be able to help increase the economic income of the poor, which at the same time helps the government in improving the country's economy.
Limitation – The indicators used to measure the level of effectiveness are still too general. A more specific perspective is needed.Practical Implication – This researeh shows Through this research, it is hoped that it will be able to minimize the occurrence of misuse in the management of aid funds for Joint Business Groups. Thus it can optimize the achievement of goals, namely increasing the community's economy which will have an impact on increasing the standard of living and welfare of the Peureulak people.
SAFETY EVALUATION OF AQUEOUS EXTRACT OF Solanum nigrum LEAF IN ANASTROZOLE-INDUCED POLYCYSTIC OVARIAN SYNDROME IN WISTAR RATS
Authors: Femi-Olabisi Fehintoluwa Joy , Adesoji Precious Adeola , Agboola Anthonia Oluyemi , Oladoye Odunayo Olowolehin 
Published: March 2024

Polycystic ovary syndrome (PCOS) is a complex endocrine disorder prevalent among women of reproductive age. Solanum nigrum leaf is used traditionally in the treatment of various gynecological disorders. The toxicological effects of aqueous extract of Solanum nigrum leaves (AESNL) at 200 mg/kg body weight on anastrozole-induced in polycystic ovarian syndrome was investigated in female Wistar rats. Sixteen female Wistar rats (190.56 ± 5.35g) were assigned into 4 groups (A - D) of four animals each: animals in group A received 0.5 ml of distilled water orally on daily basis for 14 days while the anastrozole-induced rats in groups B, C, and D also received orally 0.5 ml of distilled water, 7.14mg/kg of metformin (reference drug) and same volume of the extract corresponding to 200 mg/kg body weight of AESNL respectively. Parameters assayed for were liver function tests, kidney function tests and enzyme assays. The result obtained revealed that AESNL mitigated anastrozole-treatment related increases in albumin, uric acid, total protein parameters, total bilirubin, liver and serum aspartate aminotransferase, kidney alkaline phosphatase, liver gamma-glutamyl transferase activities, and aggravated the increases in urea, direct bilirubin, creatinine, liver and serum alkaline phosphatase, and serum gamma-glutamyl transferase activities. Therefore, the aqueous extract of Solanum nigrum leaves at the 200 mg/kg body weight might not be completely safe when used in the treatment of PCOS due to alterations in toxicological parameters evaluated in this study.
Prevalence and intensity of dental caries in children of different age groups living in the Solntsevo district, Moscow
Authors: Voronin P. A. , Voronin V. A. , Koparzova O. A. , Sagitdinova T. N. , Smirnova D. A. , Rassadina S. S. 
Published: March 2024

The relevance of the study of the prevalence and intensity of caries in children of different age groups increases due to the fact that the tasks of modern pediatric dentistry include improving the level of care and prevention of caries and its complications.Aim. The purpose of this study is to assess the prevalence and intensity of caries of temporary and permanent teeth in children and adolescents of different age groups (3–5 years, 6–8 years, 9–11 years and 12–16 years) living in the Solntsevo district of Moscow.Material and methods. The study included 1,725 children of four age groups who underwent a routine dental examination in dental departments of hospitals, preschool and school institutions of the Solntsevo district with registration of the presence of carious cavities, fillings and removed teeth.Results. The prevalence of caries in children of different age groups varies depending on the factors affecting the development of caries. The prevalence and intensity increase during the period of milk bite, then drop sharply by the beginning of the period of tooth change, then gradually increasing by the time the formation of a permanent bite is completed. Most of the children are not sanitized at the time of examination.Conclusion. Preventive measures in preschool and school institutions, the level and nature of dental care for children in the Solntsevo district of Moscow are insufficient, since the increase in caries in children of different age groups of the district exceeds acceptable indicators, as a result of which many of the examined have carious cavities.
Comparative analysis of the results of using individual titanium frameworks and resorbable collagen membranes in alveolar bone reconstruction
Authors: Nalchajyan H. M. , Ivanov S. Yu. , Ivashkevich S. G. , Mokrenko M. E. , Dolgalev A. A. , Choniashvili D. Z. 
Published: March 2024

This article describes a method of directed bone regeneration (DBR) of alveolar bone using 3D printed individual titanium framework membranes (ITFMs). Using computer modelling and additive technologies, we have designed and manufactured ITFMs for directed bone regeneration. The use of such membranes made it possible to reduce the duration of operations and obtain a larger volume of bone regenerate. Barrier membranes made of cross-linked collagen with a long resorption time were used as a comparison group.Results. The use of ICTM for alveolar bone reconstruction allowed us to achieve a maximum bone regenerate height of 6.28 mm, while using Lamina collagen membrane – 2.75 mm. The median difference of bone height before and after surgery with ICTM was 3.605 mm, for Lamina – 1.33 mm. The obtained results allowed us to recommend the use of Lamina membrane for restoration of alveolar bone width and/or height within 3 mm. In case of combined defects of alveolar bone width and height of more than 3 mm, we recommend the use of customized 3D printed titanium frame membranes.
Association between loss of hypercoagulable phenotype, clinical features and complement pathway consumption in COVID-19
Authors: Kasugai Daisuke , Tanaka Taku , Suzuki Takako , Ito Yoshinori , Nishida Kazuki , Ozaki Masayuki , Kutsuna Takeo , Yokoyama Toshiki , Kaneko Hitoshi , Ogata Ryo , Matsui Ryohei , Goshima Takahiro , Hamada Hiroshi , Ishii Azusa , Kodama Yusuke , Jingushi Naruhiro , Ishikura Ken , Kamidani Ryo , Tada Masashi , Okada Hideshi , Yamamoto Takanori , Goto Yukari 
Published: March 2024

BackgroundCoronavirus disease 2019 (COVID-19) features a hypercoagulable state, but therapeutic anticoagulation effectiveness varies with disease severity. We aimed to evaluate the dynamics of the coagulation profile and its association with COVID-19 severity, outcomes, and biomarker trajectories.MethodsThis multicenter, prospective, observational study included patients with COVID-19 requiring respiratory support. Rotational thromboelastometry findings were evaluated for coagulation and fibrinolysis status. Hypercoagulable status was defined as supranormal range of maximum clot elasticity in an external pathway. Longitudinal laboratory parameters were collected to characterize the coagulation phenotype.ResultsOf 166 patients, 90 (54%) were severely ill at inclusion (invasive mechanical ventilation, 84; extracorporeal membrane oxygenation, 6). Higher maximum elasticity (P=0.02) and lower maximum lysis in the external pathway (P=0.03) were observed in severely ill patients compared with the corresponding values in patients on non-invasive oxygen supplementation. Hypercoagulability components correlated with platelet and fibrinogen levels. Hypercoagulable phenotype was associated with favorable outcomes in severely ill patients, while normocoagulable phenotype was not (median time to recovery, 15 days vs. 27 days, P=0.002), but no significant association was observed in moderately ill patients. In patients with severe COVID-19, lower initial C3, minimum C3, CH50, and greater changes in CH50 were associated with the normocoagulable phenotype. Changes in complement components correlated with dynamics of coagulation markers, hematocrit, and alveolar injury markers.ConclusionsWhile hypercoagulable states become more evident with increasing severity of respiratory disease in patients with COVID-19, normocoagulable phenotype is associated with triggered by alternative pathway activation and poor outcomes.
Disease-modifying therapy in progressive multiple sclerosis: a systematic review and network meta-analysis of randomized controlled trials
Authors: Wu Xin , Wang Shixin , Xue Tao , Tan Xin , Li Jiaxuan , Chen Zhouqing , Wang Zhong 
Published: March 2024

BackgroundCurrently, disease-modifying therapies (DMTs) for progressive multiple sclerosis (PMS) are widely used in clinical practice. At the same time, there are a variety of drug options for DMTs, but the effect of the drugs that can better relieve symptoms and improve the prognosis are still inconclusive.ObjectivesThis systematic review aimed to evaluate the efficacy and safety of DMTs for PMS and to identify the best among these drugs.MethodsMEDLINE, EMBASE, the Cochrane Library, and clinicaltrials.gov were systematically searched to identify relevant studies published before 30 January, 2023. We assessed the certainty of the evidence using the confidence in the network meta-analysis (CINeMA) framework. We estimated the summary risk ratio (RR) for dichotomous outcomes and mean differences (MD) for continuous outcomes with 95% credible intervals (CrIs).ResultsWe included 18 randomized controlled trials (RCTs) involving 9,234 patients in the study. DMT can effectively control the disease progression of MS. Among them, mitoxantrone, siponimod, and ocrelizumab are superior to other drug options in delaying disease progression (high certainty). Mitoxantrone was the best (with high certainty) for mitigating deterioration (progression of disability). Ocrelizumab performed best on the pre- and post-treatment Timed 25-Foot Walk test (T25FW; low certainty), as did all other agents (RR range: 1.12–1.05). In the 9-Hole Peg Test (9HPT), natalizumab performed the best (high certainty), as did all other agents (RR range: 1.59–1.09). In terms of imaging, IFN-beta-1b performed better on the new T2 hypointense lesion on contrast, before and after treatment (high certainty), while siponimod performed best on the change from baseline in the total volume of lesions on T2-weighted image contrast before and after treatment (high certainty), and sWASO had the highest area under the curve (SUCRA) value (100%). In terms of adverse events (AEs), rituximab (RR 1.01), and laquinimod (RR 1.02) were more effective than the placebo (high certainty). In terms of serious adverse events (SAEs), natalizumab (RR 1.09), and ocrelizumab (RR 1.07) were safer than placebo (high certainty).ConclusionDMTs can effectively control disease progression and reduce disease deterioration during the treatment of PMS.Systematic review registrationhttps://inplasy.com/?s=202320071, identifier: 202320071.