bluuebunny/crossref_metadata_2025_split huggingface dataset:
“It's purely mutual respect”: Cross‐cultural taboos and the everyday reproduction of Singaporean nationalism
Authors: Kathiravelu Laavanya , Pandian Sharad 
Published: March 2024

AbstractWhile differences often threaten ethnonationalist projects, the Singaporean state has rendered a particular configuration of racial‐religious diversity constitutive of nationalism in the city‐state. In this paper, we approach nationalism through an often‐overlooked avenue: intangible heritage such as everyday myths, customs, and taboos. A total of 150 interviews were conducted in three neighbourhoods in Singapore, where guided conversations were conducted regarding common customs, myths, and taboos in individuals’ families and communities. We found that respondents imagined their (state‐designated) racial‐religious groups as communities of shared customs, while also demonstrating familiarity, even deference, to the customs of other groups. However, this intimacy with other groups’ practices did not undermine the integrity of respondents’ own group identity, since they remained committed to their cultural practices as embodying ancient and useful – even “scientific” – knowledge. The data thus showed that citizens are deeply reflexive about the nature, origins, and justification of the practices they undertake. This domain of everyday practices was neither simply defined into being by the state, nor is it some heroic realm of defiance: instead, it is one where people display creativity and agency in making sense of cherished cultural similarities and differences, all while using state‐prescribed categories as resources for their meaning‐making.
Gender, teacher, and school characteristics as predictors of advanced placement physics performance
Authors: Krakehl Robert , Kelly Angela M. , Khosla Puneet 
Published: March 2024

AbstractAdvanced placement (AP) physics performance is an important metric for examining precollege student preparation for post‐secondary study. The present study examined potential predictors of AP Physics 1 performance including gender, teacher, and school‐level characteristics. A theoretical framework proposed teacher preparation and experiential variables are predictive of student outcomes, in addition to contextual variables that include demographics and academic offerings. Data showed that AP Physics 1 participants varied statistically from the overall high school population in terms of gender and ethnicity, with more women, White, and Asian students enrolled. AP Physics 1 teachers tended to be more experienced than other physics teachers. A multivariable linear regression model indicated significant negative predictors included female gender and socioeconomic status; the sole positive academic predictor was whether the school offered AP Chemistry. Notably, physics performance was not predicted by physics teacher characteristics including gender, certification type, years of experience, course load in physics, and isolation. Physics performance was also unrelated to school size, AP Physics enrollment, and access to AP Biology and Calculus. Results suggest that targeted resources should be identified to support teachers in high poverty schools, and training them to enact strategies that diminish gender achievement gaps.
The neurorehabilitation of post‐stroke dysphagia: Physiology and pathophysiology
Authors: Sasegbon Ayodele , Cheng Ivy , Hamdy Shaheen 
Published: March 2024

AbstractSwallowing is a complex process involving the precise contractions of numerous muscles of the head and neck, which act to process and shepherd ingested material from the oral cavity to its eventual destination, the stomach. Over the past five decades, information from animal and human studies has laid bare the complex network of neurones in the brainstem, cortex and cerebellum that are responsible for orchestrating each normal swallow. Amidst this complexity, problems can and often do occur that result in dysphagia, defined as impaired or disordered swallowing. Dysphagia is common, arising from multiple varied disease processes that can affect any of the neuromuscular structures involved in swallowing. Post‐stroke dysphagia (PSD) remains the most prevalent and most commonly studied form of dysphagia and, as such, provides an important disease model to assess dysphagia physiology and pathophysiology. In this review, we explore the complex neuroanatomical processes that occur during normal swallowing and PSD. This includes how strokes cause dysphagia, the mechanisms through which natural neuroplastic recovery occurs, current treatments for patients with persistent dysphagia and emerging neuromodulatory treatments.
image
State-of-Health Estimation for Sustainable Electric Vehicle Batteries Using Temporal-Enhanced Self-Attention Graph Neural Networks
Authors: Zhao Yixin , Behdad Sara 
Published: March 2024

Abstract
Electric vehicles (EVs) have emerged as an environmentally friendly alternative to conventional fuel vehicles. Lithium-ion batteries are the major energy source for EVs, but they degrade under dynamic operating conditions. Accurate estimation of battery state of health is important for sustainability as it quantifies battery condition, influences reuse possibilities, and helps alleviate capacity degradation, which finally impacts battery lifespan and energy efficiency. In this paper, a self-attention graph neural network combined with long short-term memory (LSTM) is introduced by focusing on using temporal and spatial dependencies in battery data. The LSTM layer utilizes a sliding window to extract temporal dependencies in the battery health factors. Two different approaches to the graph construction layer are subsequently developed: health factor-based and window-based graphs. Each approach emphasizes the interconnections between individual health factors and exploits temporal features in a deeper way, respectively. The self-attention mechanism is used to compute the adjacent weight matrix, which measures the strength of interactions between nodes in the graph. The impact of the two graph structures on the model performance is discussed. The model accuracy and computational cost of the proposed model are compared with the individual LSTM and gated recurrent unit (GRU) models.
Flow Physics of a Rotating Bernoulli Pad: A Numerical Study
Authors: Tomar Anshul S. , Hellum Aren , Kamensky Kristina , Mukherjee Ranjan 
Published: March 2024

Abstract
Bernoulli pads are traditionally used for noncontact pick-and-place operations in industry. The normal force produced by a Bernoulli pad allows it to adhere to an object or workpiece. In addition to the normal force, the pad produces shear forces, which allows it to clean a workpiece without contact. A direct relationship between the inlet fluid power and the shear losses motivates us to explore other methods of providing power to the system with the objective of increasing shear forces and thereby improving cleaning efficacy. Here, we numerically investigate a system in which additional mechanical power is added by rotating the Bernoulli pad. The rotating system provides additional fluid forces (normal and shear) for the same inlet fluid power. For a specific pad that we investigated, the maximum wall shear stress increased by ≈15% and the normal force changed from +1.4 N (repulsive) to −6.6 N (attractive) for change in the rotational speed by 60 rad/s. Also, for a given normal attractive force, a stable equilibrium configuration can exist for two mass flow rates, with the higher mass flowrate resulting in a higher stiffness of the flow field.
Influence of Permeability and Shear-Thinning Behavior on the Hydrodynamics Flow Features Around Porous Square Cylinders
Authors: Jamshed Saqib , Dhiman Amit Kumar 
Published: March 2024

Abstract
This article investigates the laminar flow of power-law fluids through two porous square cylinders in a side-by-side configuration. The effects of power-law index (n), Darcy number (Da), and gap ratio (g/W) are examined within ranges of g/W = 0.5–5, n = 0.4–0.8, and Da = 10−6–10−2, respectively. Two flow conditions are considered: first, for a creeping flow (unseparated flow) at Re = 1 where Darcy's law is applicable; second, for a viscous dominant flow at Re = 100, where Darcy–Forchheimer-extended model is exercised. Flow patterns behind the porous cylinders are analyzed using streamlines, velocity profiles, pressure distribution curves, and vorticity structural parameters (Г). In low permeability levels, the flow exhibits an irregular nonperiodic vortex shedding characterized by a single large vortex street far off the downstream for g/W = 0.5. However, synchronized wake patterns were observed in either antiphase or in-phase modes for higher gap ratios. Leading-edge separation with two-side recirculation induces quasi-periodicity in the flow for all g/W. It was found that increasing the permeability can prevent the leading edge separation. Additionally, a transition from antiphase to in-phase mode occurs when the permeability is altered while maintaining constant flow-time. The presence of a jet-like flow between cylinders significantly impacts unsteady wake patterns. The impact of g/W, power-law index, and permeability on drag is also examined. A jump in some flow parameters was observed at higher Re for the midrange Darcy number, but no such increase was noted for the high shear-thinning behavior. These findings provide a potential approach for improving the design of fluidic systems involving porous cylinders.
A nanochitosan-D-galactose formulation increases the accumulation of primaquine in the liver
Authors: Gomes F. , Ribeiro A. C. , Sanches G. S. , Borges H. S. , Takahashi L. A. U. , Daniel-Ribeiro C. T. , Tedesco A. C. , Nascimento J. W. L. , Carvalho L. J. M. 
Published: March 2024

ABSTRACT

Primaquine is the mainstream antimalarial drug to prevent
Plasmodium vivax
relapses. However, this drug can induce hemolysis in patients with glucose-6-phosphate dehydrogenase deficiency. Nanostructure formulations of primaquine loaded with D-galactose were used as a strategy to target the drug to the liver and decrease the hemolytic risks. Nanoemulsion (NE-Pq) and nanochitosan (NQ-Pq) formulations of primaquine diphosphate containing D-galactose were prepared and characterized by their physicochemistry properties. Pharmacokinetic and biodistribution studies were conducted using Swiss Webster mice. A single dose of 10 mg/kg of each nanoformulation or free primaquine solution was administered by gavage to the animals, which were killed at 0.5, 1, 2, 4, 8, and 24 hours. Blood samples and tissues were collected, processed, and analyzed by high-performance liquid chromatography. The nanoformulation showed sizes around 200 nm (NE-Pq) and 400 nm (NQ-Pq) and physicochemical stability for over 30 days. Free primaquine solution achieved higher primaquine Cmax in the liver than NE-Pq or NQ-Pq at 0.5 hours. However, the half-life and mean residence time (MRT) of primaquine in the liver were three times higher with the NQ-Pq formulation than with free primaquine, and the volume distribution was four times higher. Conversely, primaquine’s half-life, MRT, and volume distribution in the plasma were lower for NQ-Pq than for free primaquine. NE-Pq, on the other hand, accumulated more in the lungs but not in the liver. Galactose-coated primaquine nanochitosan formulation showed increased drug targeting to the liver compared to free primaquine and may represent a promising strategy for a more efficient and safer radical cure for vivax malaria.
Clinical and genomic characteristics of IMP-producing
Enterobacter cloacae
complex and
Klebsiella pneumoniae
Authors: Suzuki Daisuke , Sakurai Aki , Wakuda Mitsutaka , Suzuki Masahiro , Doi Yohei 
Published: March 2024

ABSTRACT

Carbapenemase-producing
Enterobacterales
(CPEs) are one of the top priority antimicrobial-resistant pathogens. Among CPEs, those producing acquired metallo-β-lactamases (MBLs) are considered particularly problematic as few agents are active against them. Imipenemase (IMP) is the most frequently encountered acquired MBL in Japan, but comprehensive assessment of clinical and microbiological features of IMP-producing
Enterobacterales
infection remains scarce. Here, we retrospectively evaluated 62 patients who were hospitalized at a university hospital in Japan and had IMP-producing
Enterobacterales
from a clinical culture. The isolates were either
Enterobacter cloacae
complex or
Klebsiella pneumoniae
, and most of them were isolated from sputum. The majority of
K. pneumoniae,
but not
E. cloacae
complex isolates, were susceptible to aztreonam. Sequence type (ST) 78 and ST517 were prevalent for
E. cloacae
complex and
K. pneumoniae
, respectively, and all isolates carried
bla
IMP-1
. Twenty-four of the patients were deemed infected with IMP-producing
Enterobacterales
. Among the infected patients, therapy varied and largely consisted of conventional β-lactam agents, fluoroquinolones, or combinations. Three (13%), five (21%), and nine (38%) of them died by days 14, 30, and 90, respectively. While incremental mortality over 90 days was observed in association with underlying comorbidities, active conventional treatment options were available for most patients with IMP-producing
Enterobacterales
infections, distinguishing them from more multidrug-resistant CPE infections associated with globally common MBLs, such as New Delhi metallo-β-lactamase (NDM) and Verona integron-encoded metallo-β-lactamase (VIM).
Gliding motility proteins GldJ and SprB contribute to
Flavobacterium columnare
virulence
Authors: Thunes Nicole C. , Evenhuis Jason P. , Lipscomb Ryan S. , Pérez-Pascual David , Stevick Rebecca J. , Birkett Clayton , Ghigo Jean-Marc , McBride Mark J. 
Published: March 2024

ABSTRACT

Flavobacterium columnare
causes columnaris disease in fish. Columnaris disease is incompletely understood, and adequate control measures are lacking. The type IX secretion system (T9SS) is required for
F. columnare
gliding motility and virulence. The T9SS and gliding motility machineries share some, but not all, components. GldN (required for gliding and for secretion) and PorV (involved in secretion but not required for gliding) are both needed for virulence, implicating T9SS-mediated secretion in virulence. The role of motility in virulence is uncertain. We constructed and analyzed
sprB
,
sprF
, and
gldJ
mutants that were defective for motility but that maintained T9SS function to understand the role of motility in virulence. Wild-type cells moved rapidly and formed spreading colonies. In contrast,
sprB
and
sprF
deletion mutants were partially defective in gliding and formed nonspreading colonies. Both mutants exhibited reduced virulence in rainbow trout fry. A
gldJ
deletion mutant was nonmotile, secretion deficient, and avirulent in rainbow trout fry. To separate the roles of GldJ in secretion and in motility, we generated
gldJ
truncation mutants that produce nearly full-length GldJ. Mutant
gldJ
563
, which produces GldJ truncated at amino acid 563, was defective for gliding but was competent for secretion as measured by extracellular proteolytic activity. This mutant displayed reduced virulence in rainbow trout fry, suggesting that motility contributes to virulence. Fish that survived exposure to the
sprB
deletion mutant or the
gldJ
563
mutant exhibited partial resistance to later challenge with wild-type cells. The results aid our understanding of columnaris disease and may suggest control strategies.

IMPORTANCE

Flavobacterium columnare
causes columnaris disease in many species of freshwater fish in the wild and in aquaculture systems. Fish mortalities resulting from columnaris disease are a major problem for aquaculture.
F. columnare
virulence is incompletely understood, and control measures are inadequate. Gliding motility and protein secretion have been suggested to contribute to columnaris disease, but evidence directly linking motility to disease was lacking. We isolated and analyzed mutants that were competent for secretion but defective for motility. Some of these mutants exhibited decreased virulence. Fish that had been exposed to these mutants were partially protected from later exposure to the wild type. The results contribute to our understanding of columnaris disease and may aid development of control strategies.
Determination of minimum inhibitory concentrations using machine-learning-assisted agar dilution
Authors: Gerada Alessandro , Harper Nicholas , Howard Alex , Reza Nada , Hope William 
Published: March 2024

ABSTRACT

Effective policy to address the global threat of antimicrobial resistance requires robust antimicrobial susceptibility data. Traditional methods for measuring minimum inhibitory concentration (MIC) are resource intensive, subject to human error, and require considerable infrastructure. AIgarMIC streamlines and standardizes MIC measurement and is especially valuable for large-scale surveillance activities. MICs were measured using agar dilution for
n
= 10 antibiotics against clinical Enterobacterales isolates (
n
= 1,086) obtained from a large tertiary hospital microbiology laboratory.
Escherichia coli
(
n
= 827, 76%) was the most common organism. Photographs of agar plates were divided into smaller images covering one inoculation site. A labeled data set of colony images was created and used to train a convolutional neural network to classify images based on whether a bacterial colony was present (first-step model). If growth was present, a second-step model determined whether colony morphology suggested antimicrobial growth inhibition. The ability of the AI to determine MIC was then compared with standard visual determination. The first-step model classified bacterial growth as present/absent with 94.3% accuracy. The second-step model classified colonies as “inhibited” or “good growth” with 88.6% accuracy. For the determination of MIC, the rate of essential agreement was 98.9% (644/651), with a bias of −7.8%, compared with manual annotation. AIgarMIC uses artificial intelligence to automate endpoint assessments for agar dilution and potentially increases throughput without bespoke equipment. AIgarMIC reduces laboratory barriers to generating high-quality MIC data that can be used for large-scale surveillance programs.

IMPORTANCE
This research uses modern artificial intelligence and machine-learning approaches to standardize and automate the interpretation of agar dilution minimum inhibitory concentration testing. Artificial intelligence is currently of significant topical interest to researchers and clinicians. In our manuscript, we demonstrate a use-case in the microbiology laboratory and present validation data for the model’s performance against manual interpretation.
Application of the 187Re-187Os geochronometer to crustal materials: Systematics, methodology, data reporting, and interpretation
Authors: Rooney Alan D. , Hnatyshin Danny , Toma Jonathan , Saintilan Nicolas J. , Millikin Alexie E.G. , Selby David , Creaser Robert A. 
Published: March 2024

Abstract
The rhenium-osmium (187Re-187Os) system is a highly versatile chronometer that is regularly applied to a wide range of geological and extraterrestrial materials. In addition to providing geo- or cosmo-chronological information, the Re-Os system can also be used as a tracer of processes across a range of temporal (millennial to gigayear) and spatial scales (lower mantle to cryosphere). An increasing number of sulfide minerals are now routinely dated, which further expands the ability of this system to refine mineral exploration models as society moves toward a new, green economy with related technological needs. An expanding range of natural materials amenable to Re-Os geochronology brings additional complexities in data interpretation and the resultant translation of measured isotopic ratios to a properly contextualized age. Herein, we provide an overview of the 187Re-187Os system as applied to sedimentary rocks, sulfides, and other crustal materials and highlight further innovations on the horizon. Additionally, we outline next steps and best practices required to improve the precision of the chronometer and establish community-wide data reduction procedures, such as the decay constant, regression technique, and software packages to use. These best practices will expand the utility and viability of published results and essential metadata to ensure that such data conform to evolving standards of being findable, accessible, interoperable, and reusable (FAIR).
Exceptional preservation of a marine tapeworm tentacle in Cretaceous amber
Authors: Luo Cihang , Palm Harry W. , Zhuang Yuhui , Jarzembowski Edmund A. , Nyunt Thet Tin , Wang Bo 
Published: March 2024

Abstract
Parasites are ubiquitous in extant ecosystems but rarely preserved in the geological record, especially parasitic worms (helminths). One such group is Cestoda (tapeworms), a specialized endoparasitic group of platyhelminths (flatworms). They have a complex lifecycle with at least two hosts, infecting all major groups of vertebrates. However, their fossil record is extremely sparse due to their soft tissue and concealed habitats, with the only widely accepted example before the Quaternary being eggs discovered in a shark coprolite from the Permian. The lack of body fossils greatly hampers our understanding of their early evolution. We report a slender, armed fossil from mid-Cretaceous Kachin (Myanmar) amber (ca. 99 Ma). This fossil displays unique external (armature pattern) and internal (partially invaginated tentacle and rootless hooks) features that are most consistent with the tentacles of extant trypanorhynch tapeworms that parasitize marine elasmobranchs (mainly sharks and rays). Our study thus probably provides not only the first partial body fossil of a tapeworm, but also arguably the most convincing body fossil of a flatworm. In addition, the exquisite invaginated tentacle inside the fossil highlights that amber can preserve the internal structure of helminths. Remarkably, nearly all extant trypanorhynchs are endoparasites of marine elasmobranchs, thus our study provides an exceptional example of a marine endoparasite trapped in terrestrial amber.
Consensus-based quality standards for emergency departments in Palestine
Authors: Bani Odeh Abed Alra'oof , Wallis Lee A , Hamdan Motasem , Stassen Willem 
Published: March 2024

ObjectivesThe present study aimed to establish appropriate quality standards for emergency departments (EDQS) in Palestine.MethodsThe study comprised four phases. First, a comprehensive literature review was conducted to develop a framework for assessing healthcare services in EDs. Second, the initial set of EDQS was developed based on the review findings. Third, local experts provided feedback on the EDQS, suggesting additional standards, and giving recommendations. This feedback was analysed to create a preliminary set of EDQS. Finally, an expanded group of local emergency care experts evaluated the preliminary set, providing feedback on content and structure to contribute to the final set of EDQS.FindingsWe identified quality domains in EDs and categorised them into clinical and administrative pathways. The clinical pathway comprises 39 standards across 7 subdomains: triage, treatment, transportation, medication safety, patient flow and medical diagnostic services. Expert consensus was achieved on 87.5% of these standards. The administrative domain includes 64 consensus-based standards across 9 subdomains: documentation, information management systems, access-location, design, leadership, management, workforce staffing, training, equipment, supplies, capacity-resuscitation rooms, resources for a safe working environment, performance indicators and patient safety-infection prevention and control programmes.ConclusionThis study employed a rigorous approach to identify QS for EDs in Palestine. The multiphase consensus process ensured the appropriateness of the developed EDQS. Inclusion of diverse perspectives enriched the content. Future studies will validate and refine the standards based on feedback. The EDQS has potential to enhance emergency care in Palestine and serve as a model for other regions facing similar challenges.