bluuebunny/crossref_metadata_2025_split huggingface dataset:
Total Synthesis of (‐)‐Heptemerone B (I) and (‐)‐Guanacastepene E (II).
Authors: Miller Aubry K. , Hughes Chambers C. , Kennedy‐Smith Joshua J. , Gradl Stefan N. , Trauner Dirk 
Published: April 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Chaxine A, an Osteoclast‐Forming Suppressing Substance, from the Mushroom Agrocybe chanxingu.
Authors: Kawagishi Hirokazu , Akachi Takuto , Ogawa Tetsuhiro , Masuda Kikuko , Yamaguchi Kohji , Yazawa Kazunaga , Takahashi Mamoru 
Published: April 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Tryptophan 4‐Aminocinnamamides from a Myxomycete Fuligo aurea.
Authors: Hosoya Takahiro , Kato Yui , Yamamoto Yukinori , Hayashi Masahiko , Komiyama Kanki , Ishibashi Masami 
Published: April 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Facile Peptide Thioester Synthesis via Solution‐Phase Tosylamide Preparation.
Authors: Manabe Shino , Sugioka Tomoyuki , Ito Yukishige 
Published: April 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Tandem Staudinger—azaWittig Mediated Ring Expansion: Rapid Access to New Isofagomine‐Tetrahydroxyazepane Hybrids.
Authors: Li Hongqing , Zhang Yongmin , Vogel Pierre , Sinay Pierre , Bleriot Yves 
Published: April 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Exiguamine A, an Indoleamine‐2,3‐dioxygenase (IDO) Inhibitor Isolated from the Marine Sponge Neopetrosia exigua.
Authors: Brastianos Harry C. , Vottero Eduardo , Patrick Brian O. , Van Soest Rob , Matainaho Teatulohi , Mauk A. Grant , Andersen Raymond J. 
Published: April 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Polymorphism of Aspirin: Crystalline Aspirin as Intergrowths of Two “Polymorphic” Domains.
Authors: Bond Andrew D. , Boese Roland , Desiraju Gautam R. 
Published: April 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Electron Paramagnetic Resonance Study of Phosphorus‐Doped n‐Type Homoepitaxial Diamond Films Grown by Chemical Vapor Deposition
Authors: Katagiri M. , Isoya J. , Koizumi S. , Kanda H. 
Published: April 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Dinuclear Ruthenium and Osmium Arene Trihydrido Complexes: Versatile Water‐Soluble Synthons in Organometallic Chemistry.
Authors: Suess‐Fink Georg , Therrien Bruno 
Published: April 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
The aza‐Wittig Reaction: An Efficient Tool for the Construction of Carbon—Nitrogen Double Bonds
Authors: Palacios Francisco , Alonso Concepcion , Aparicio Domitila , Rubiales Gloria , de los Santos Jesus M. 
Published: April 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Development of Efficient Methods for Synthesis of Nitrogen‐Containing Compounds Using Carbamates, Acylhydrazines, and Ammonia
Authors: Sugiura Masaharu 
Published: April 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Recent Advances in Antimalarial Drug Development
Authors: Vangapandu Suryanaryana , Jain Meenakshi , Kaur Kirandeep , Patil Premanand , Patel Sanjay R. , Jain Rahul 
Published: April 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
New Developments in Natural Products‐Based anti‐AIDS Research
Authors: Yu Donglei , Morris‐Natschke Susan L. , Lee Kuo‐Hsiung 
Published: April 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
New Developments in the Chemistry and Biology of the Bioactive Constituents of Tanshen
Authors: Wang Xihong , Morris‐Natschke Susan L. , Lee Kuo‐Hsiung 
Published: April 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
The Role of Lipd Rafts in Trimeric G Protein‐Mediated Signal Transduction
Authors: Ohkubo Satoko , Nakahata Norimichi 
Published: April 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Anaerobic Membrane Bioreactors: Applications and Research Directions
Authors: Liao Bao‐Qiang , Kraemer Jeremy T. , Bagley David M. 
Published: April 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Advanced Instrumental Approaches for Characterization of Marine Dissolved Organic Matter: Extraction Techniques, Mass Spectrometry, and Nuclear Magnetic Resonance Spectroscopy
Authors: Mopper Kenneth , Stubbins Aron , Ritchie Jason D. , Bialk Heidi M. , Hatcher Patrick G. 
Published: April 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Clinical characteristics and outcomes of hypertrophic cardiomyopathy in Taiwan—a tertiary center experience
Authors: Lee Cheng‐Han , Liu Ping‐Yen , Lin Li‐Jen , Chen Jyh‐Hong , Tsai Liang‐Miin 
Published: April 2007

AbstractBackgroundMost information concerning hypertrophic cardiomyopathy has been derived from western countries and Japan.HypothesisPatients with hypertrophic cardiomyopathy in Taiwan may have a distinct morphology and clinical picture.MethodsInformation from 163 consecutive patients with hypertrophic cardiomyopathy at a medical center in Taiwan from 1990 through 2005 was retrospectively collected. The diagnosis of hypertrophic cardiomyopathy required echocardiographic demonstration of left ventricular hypertrophy (wall thickness ≥ mm during diastole) in a specific region or with diffuse distribution. Follow‐up information was obtained from medical records.ResultsAmong 163 patients (male, 52%), the mean follow‐up period was 5.3 ± 4.1 years. Men had nearly a threefold increase in prevalence of apical hypertrophic cardiomyopathy (23.8% vs. 8.9%, p = 0.03), younger onset of initial evaluation (57.2 ± 12.9 vs. 64.8 ± 11.3, p < 0.001), and lower prevalence of hypertrophic obstructive cardiomyopathy (33.3% vs. 63.3%, p < 0.001) compared to women. Fifty‐eight patients (35.6%) experienced cardiovascular events, of which pulmonary edema and paroxysmal atrial fibrillation were the most common (19.7% and 12.3%, respectively). The annual cardiovascular mortality rate was 0.8%. In multivariate analysis, left ventricular outflow obstruction [odds ratio (OR): 4.92, p = 0.001], atrial fibrillation (OR: 3.53, p = 0.014), and female gender (OR: 2.99, p = 0.043) were independent predictors of mortality.ConclusionsHypertrophic cardiomyopathy did not significantly increase cardiovascular mortality rate, but over one‐third of patients with hypertrophic cardiomyopathy experienced cardiovascular events. High prevalence of left ventricular outflow obstruction especially in elderly women was observed. Left ventricular outflow obstruction, atrial fibrillation, and female gender were predictors of mortality. Copyright © 2007 Wiley Periodicals, Inc.
A risk‐predictive score for cardiogenic shock after acute myocardial infarction in Chinese patients
Authors: Zhang Min , Li Jian , Cai Yi Ming , Ma Hong , Xiao Jian Ming , Liu Jian , Zhao Ling , Guo Tao , Han Ming Hua 
Published: April 2007

AbstractBackgroundCardiogenic shock after acute myocardial infarction (AMI) remains a poor prognosis. Although numerous studies discussed the predictors of cardiogenic shock complicating AMI, the data in Chinese patients is still absent. The goal of this study is to develop a risk‐predictive score for cardiogenic shock after AMI, among Chinese patients, so as to guide clinicians to prevent cardiogenic shock.MethodsPatients with ST‐segment elevated AMI were provided by two Chinese hospitals from 1994 to 2004. Baseline characteristics of each case were documented. Multivariable logistic regression modeling techniques were used to develop a model to predict the occurrence of cardiogenic shock within 72 h after admission. On the basis of the coefficients in the model, a risk score was developed for the probability of cardiogenic shock. To test its viability, another population, which was consistent with the original population, confirmed the scoring.ResultsAmong 2,077 patients, 184 cases developed cardiogenic shock within 72 h. Age, gender, BMI, killip class, MI location, multivessel disease, previous MI, family history of CAD, and thrombolytic therapy were strong predictors for shock after AMI. A risk‐predictive score for shock was developed. It predicted cardiogenic shock accurately in another Chinese population.ConclusionsA predictive model is developed in Chinese patients with AMI for the first time. It is based on some simple parameters, which can be easily obtained by clinicians. The risk score derived from the model can predict cardiogenic shock accurately. Copyright © 2007 Wiley Periodicals, Inc.
Systemic Nanoparticle Paclitaxel (nab‐Paclitaxel) for In‐stent Restenosis I (SNAPIST‐I): A First‐in‐Human Safety and Dose‐finding Study
Authors: Margolis James , McDonald John , Heuser Richard , Klinke Peter , Waksman Ron , Virmani Renu , Desai Neil , Hilton David 
Published: April 2007

AbstractBackgroundPaclitaxel‐eluting stents inhibit restenosis; however, this technology has drawbacks (e.g., stent thrombosis, requirement for long‐term antiplatelet ther‐ apy, and cost—particularly for patients with multivessel disease). Systemic treatment with a novel 130‐nm, albumin‐bound particle form of paclitaxel (nab‐paclitaxel) has been shown to reduce restenosis in animals.HypothesisThis study was designed to establish the safety and optimal dose of systemic nab‐paclitaxel for reducing in‐stent restenosis in humans. If well tolerated, systemic nab‐paclitaxel may be used with any available bare‐metal stent and at potentially lower cost than drug‐eluting stents.MethodsPatients received nab‐paclitaxel 10, 30, 70, or 100 mg/m2 intravenously after stenting of a single de novo lesion ≥ 3 mm in diameter. Study endpoints included safety and major adverse cardiac events (MACE) at 2 and 6 months.ResultsData were obtained for all 23 enrolled patients (mean age 66 ± 10 years, 74% men, 26% with diabetes). No significant adverse events (AE) were attributable to nab‐paclitaxel at 10 or 30 mg/m2. Moderate neutropenia, moderate sensory neuropathy, and mild to moderate, reversible alopecia occurred only at doses of 70 and 100 mg/m2; therefore, doses of 70 mg/m2 or higher were considered unacceptable in this patient population. No MACE were reported at 2 months. At 6 months, 4 target lesion revascularizations (TLR) for restenoses were reported (2 each in the 10‐ and 100‐mg/m2‐dose groups).ConclusionsSystemic nab‐paclitaxel was well tolerated at doses below 70 mg/m2 in this group of patients; no unexpected AE were noted. Additional studies are under way to explore intravenous and intracoronary administration of nab‐paclitaxel. Copyright © 2007 Wiley Periodicals, Inc.
The prevalence of prehypertension and hypertension among rural adults in liaoning province of China
Authors: Sun Zhaoqing , Zheng Liqiang , Wei Yidong , Li Jue , Zhang Xinzhong , Zhang Xingang , Liu Shuangshuang , Xu Changlu , Li Jiajin , Zhao Fenfen , Dong Guanghui , Hu Dayi , Sun Yingxian 
Published: April 2007

AbstractBackgroundThe objective of this study was to estimate the prevalence of prehypertension and hypertension in the rural adults of Liaoning province of China.MethodsThe study was conducted in 2004‐2006, using a multistage cluster sampling method to select a representative sample. A total of 45925 adults, 35 years or older, were examined. Two blood pressure measurements were obtained by trained observers by use of a standardized electric sphygmomanometer after a 5‐min sitting rest. Information on the history of hypertension was obtained by use of a standard questionnaire.ResultsOverall, the prevalence of prehypertension was 44.1%; for men 48.7 and women 39.6%. The prevalence of hypertension was 37.8%; for men 37.0 and women 38.6%. Among hypertensive patients, only 29.5% patients were aware of their high blood pressure, 23.6% patients were taking antihypertensive medication, and 1.1% patients achieved blood pressure control.ConclusionsPrehypertension and hypertension are highly prevalent in rural areas of China. The percentage of those with hypertension who are aware, treated, and controlled are unacceptably low. These results underscore the urgent need to develop strategies to improve prevention, detection, and treatment of hypertension in rural areas of China. Copyright © 2007 Wiley Periodicals, Inc.
A case report of simultaneous thrombosis of two coronary artery stents in association with clopidogrel resistance
Authors: Lee Jin Sun , Dunn Steven P. , Marshall Helen M. , Cohen Mauricio G. , Smyth Susan S. 
Published: April 2007

AbstractDespite aggressive antiplatelet therapy in the setting of PCI, the incidence of acute stent thrombosis remains approximately 0.5–2%. We report a patient with simultaneous thrombosis of two drug‐eluting coronary artery stents, suggesting a systemic thrombotic state. Evaluation by optical platelet aggregometry revealed clopidogrel resistance, which was overcome at a higher drug dose. We aim to highlight the potential utility of platelet function analysis to guide therapy for patients in whom inadequate antiplatelet therapy may have catastrophic clinical outcomes. Copyright © 2007 Wiley Periodicals, Inc.
Cortical actin filament organization in developing and functioning stomatal complexes of Zea mays and Triticum turgidum
Authors: Panteris Emmanuel , Galatis Basil , Quader Hartmut , Apostolakos Panagiotis 
Published: April 2007

AbstractCortical actin filament (AF) organization was studied in detail in developing stomatal complexes of the grasses Zea mays and Triticum turgidum. AF arrays during the whole stomatal complex development are dynamic, partly following the pattern of cortical microtubule (MT) organization. They also exhibit particular patterns of organization, spatially and temporarily restricted. Among AF arrays, the radial ones that underlie young guard cell (GC) periclinal walls, those that line the bulbous GC ends and the AF ring at the junction between subsidiary cells (SCs) and GCs are described here for the first time. Although many similarities in cortical AF organization exist among the stomatal cells of both plants studied, considerable differences have also been observed between them. Our data reveal that the expanding areas of stomatal cell walls are lined by distinct cortical AF aggregations that probably protect the plasmalemma against mechanical stresses. Experimental AF disruption does not seem to affect detectably stomatal cell morphogenesis. Moreover, the structural and experimental data of this study revealed that, in contrast to the elliptical stomata, in the dumbbell‐shaped ones the AFs and MTs seem not to be involved in the mechanism of opening and closing of the stomatal pore. Cell Motil. Cytoskeleton 2007. © 2007 Wiley‐Liss, Inc.
A spatiotemporal evaluation of the contribution of the dorsal mesenchymal protrusion to cardiac development
Authors: Snarr Brian S. , Wirrig Elaine E. , Phelps Aimee L. , Trusk Thomas C. , Wessels Andy 
Published: April 2007

Abstract A composite of images taken from figures in Snarr et al. Upper Left: Histological demonstration of endocardial (lacZ) and non‐endocardial derived cells in the atrioventricular (AV) mesenchyme of a Tie2‐Cre/R26R mouse heart at ED11.5. Upper Right: Superior view of an AMIRA 3D reconstruction of an ED11.5, Tie2‐Cre/R26R heart. Colors distinguish the different mesenchymal components in the AV region. Center: Left lateral view of the ED11.5 reconstruction illustrating the relationship of the different mesenchymal components to the primary atrial septum (PAS). Bottom Left: Histological demonstration of endocardial (lacZ) and non‐endocardial derived cells in the AV mesenchyme at ED13. Bottom Right: A 3D reconstruction demonstrating the spatial relationship of the different AV mesenchymal tissues at ED 13. See Snarr et al., Developmental Dynamics 236:1287–1294.
Synthesis, Reactivity and DFT Investigation of a Cationic Zirconocene Benzyl Compound with an Appended Phenyl Group
Authors: Saßmannshausen Jörg , Track Anna , Dias Tiago A. D. S. 
Published: April 2007

AbstractThe reaction of [η5‐C5H5‐(η5‐C5H4CMe2C6H4Me)Zr(CH2Ph)2](1) with the cation generating agent B(C6F5)3was studied by means of multinuclear NMR and density functional theory (DFT) methods. The clean reaction in CD2Cl2at –60 °C yielded the cationic compound [η5‐C5H5‐(η5:η1‐C5H4‐CR2C6H4R)Zr(η2‐CH2Ph)] (R = Me:2, R = H:3), with a tolyl moiety coordinated to the cationic zirconium centre, in addition to the expected η2‐coordination of the benzyl moiety. Both coordinations were unambiguously assigned by multinuclear one‐ and two‐dimensional NMR spectroscopy. Detailed DFT calculations of congener3at the B3LYP level of theory explain the unusual chemical shift of the coordinated atom of the tolyl moiety. Furthermore, detailed electronic analysis (Bader and NBO analysis) were undertaken to ascertain the type of coordination (agostic versus electrostatic) that the tolyl moiety adopts. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2007)
Comparison of Methionine α,γ‐Lyase and Homocysteine α,γ‐Lyase for Electrochemical Determination of Homocysteine
Authors: Zhao Dong , McIntosh Mike , Fein Harry , Zhang Xueji 
Published: April 2007

AbstractRecently, a novel enzymatic method was developed for determination of homocysteine. This method utilizes the electrochemical hydrogen sulfide sensor along with methionine α,γ‐lyase to accomplish the fast, accurate, sensitive and selective measurements. As a continuation of this work, another enzyme, homocysteine α,γ‐lyase, was used and the parallel experiments of using both enzymes were carried out against the effect of pH, sensitivity, linearity, and interferences, in an intended comparison between these two enzymes. The excellent linearity of amperometric currents against homocysteine concentrations, high sensitivities and low detection limits for both enzymes reconfirmed that the electrochemical method is superior over other analytical means. The high enzymatic activity of methionine α,γ‐lyase surpassing homocysteine α,γ‐lyase endowed the former higher sensitivity, lower detection limit and faster response than the latter, suggesting methionine α,γ‐lyase a better candidate for homocysteine measurement by electrochemical method. The differences between these two enzymes on the trends of response time and sensitivity at different pH environments, reactivity toward several forms of homocysteine as well as on the interference from several agents were also addressed and discussed.
Thulium(III) Ions Monitoring by a Novel Thulium(III) Microelectrode Based on a S‐N Schiff Base
Authors: Ganjali Mohammad Reza , Norouzi Parviz , Akbari‐Adergani Behrouz 
Published: April 2007

AbstractThis study presents for the first time development of a highly selective and sensitive thulium(III) micro‐sensor. Theoretical calculations were conducted on a S‐N Schiff base [thiophene‐2‐carbaldehyde‐(7‐methyl‐1,3‐benzothiazol‐2‐yl) hydrazone] (TCMH) in order to obtain a clue about the tendency of TCMH to Tm(III) and some other metal ions. Then, TCMH was used as a membrane‐active component to prepare a Tm(III)‐selective polymeric membrane microelectrode. In line with the resulting data, the electrode exhibits a Nernstian response toward Tm(III) ions for a very wide concentration range (1.0×10−11–4.0×10−6 M) with a detection limit of 1.0×10−11 (ca. 1.5 ppt) and a very fast response time in the whole concentration range (<5 s). In addition, the results showed that the certain microelectrode could be applied in the pH range of 4.0–11.0 with a usage of more than one month without any considerable potential divergence.
Zeptomole Detection of Streptavidin Using Carbon Paste Electrode and Square‐Wave Voltammetry
Authors: Petrlova Jitka , Masarik Michal , Potesil David , Adam Vojtech , Trnkova Libuse , Kizek Rene 
Published: April 2007

AbstractWe compared the suitability of avidin and streptavidin for avidin‐biotin technology in view of the sensitivity of the analysis using square‐wave voltammetry. We found out during our preliminary experiments that streptavidin gave approximately 100 times higher electrochemical response in comparison with avidin at the same experimental conditions and concentration. Thus, we used two approaches for streptavidin determination – analysis directly in electrochemical cell and analysis by adsorptive transfer technique (AdTS). Ten minutes long accumulation on carbon paste electrode surface was ascertained as optimal in both cases. Limits of detection were 0.3 aM (electrochemical cell) and 30 aM (AdTS).
A spot price of electricity algorithm applied to lossy short‐term hydrothermal scheduling problem with limited energy supply thermal units
Authors: Yaşar Celal , Fadıl Salih , Babadağı Mustafa 
Published: April 2007

AbstractA lossy electric power system including normal and limited energy supply thermal units and hydraulic units are considered in this paper. The total thermal cost for an operation period of the system is minimized under some possible electric, hydraulic, and fuel constraints. The minimization of the total thermal cost is achieved by determining active generations of all units in all subintervals by means of a spot price of electricity algorithm proposed by our research group. Application of the algorithm is demonstrated on a lossy electric power system that contains 16 buses, three normal thermal, two limited energy supply thermal and 4 hydraulic units (coupled). Obtained results are discussed in the example section of the paper. Copyright © 2007 John Wiley & Sons, Ltd.