bluuebunny/crossref_metadata_2025_split huggingface dataset:
Impact of Pre-existing Type 2 Diabetes Mellitus and Cardiovascular Disease on Healthcare Resource Utilization and Costs in Patients With COVID-19
Authors: Nguyen Chi , Crowe Christopher L. , Kuti Effie , Donato Bonnie , Djaraher Rachel , Seman Leo , Graeter Nancy , Power Thomas P. , Mehra Rinku , Willey Vincent J. 
Published: April 2024

Background: The economic burden associated with type 2 diabetes mellitus (T2DM) and concurrent cardiovascular disease (CVD) among patients with COVID-19 is unclear. Objective: We compared healthcare resource utilization (HCRU) and costs in patients with COVID-19 and T2DM and CVD (T2DM + CVD), T2DM only, or neither T2DM nor CVD (T2DM/CVD). Methods: A retrospective observational study in COVID-19 patients using data from the Healthcare Integrated Research Database (HIRD®) was conducted. Patients with COVID-19 were identified between March 1, 2020, and May 31, 2021, and followed from first diagnosis or positive lab test to the end of health plan enrollment, end of study period, or death. Patients were assigned one of 3 cohorts: pre-existing T2DM+CVD, T2DM only, or neither T2DM/CVD. Propensity score matching and multivariable analyses were performed to control for differences in baseline characteristics. Study outcomes included all-cause and COVID-19–related HCRU and costs. Results: In all, 321 232 COVID-19 patients were identified (21 651 with T2DM + CVD, 28 184 with T2DM only, and 271 397 with neither T2DM/CVD). After matching, 6967 patients were in each group. Before matching, 46.0% of patients in the T2DM + CVD cohort were hospitalized for any cause, compared with 18.0% in the T2DM-only cohort and 6.3% in the neither T2DM/CVD cohort; the corresponding values after matching were 34.2%, 26.0%, and 21.2%. The proportion of patients with emergency department visits, telehealth visits, or use of skilled nursing facilities was higher in patients with COVID-19 and T2DM + CVD compared with the other cohorts. Average all-cause costs during follow-up were $12 324, $7882, and $7277 per-patient-per-month after matching for patients with T2DM + CVD, T2DM-only, and neither T2DM/CVD, respectively. COVID-19–related costs contributed to 78%, 75%, and 64% of the overall costs, respectively. The multivariable model showed that per-patient-per-month all-cause costs for T2DM + CVD and T2DM-only were 54% and 21% higher, respectively, than those with neither T2DM/CVD after adjusting for residual confounding. Conclusion: HCRU and costs in patients were incrementally higher with COVID-19 and pre-existing T2DM + CVD compared with those with T2DM-only and neither T2DM/CVD, even after accounting for baseline differences between groups, confirming that pre-existing T2DM + CVD is associated with increased HCRU and costs in COVID-19 patients, highlighting the importance of proactive management.
BIM im Facility Management der Chemie- und Pharmaindustrie/BIM and facility management in the chemical and pharmaceutical industry
Authors: Meinen Heiko , Kock Katrin , Hübner Roman 
Published: April 2024

Ein wichtiger Anwendungsfall von Building Information Modeling ist die Optimierung der Zusammenarbeit der Projektbeteiligten in einem Bauprojekt. Dieser Beitrag befasst sich mit der Anwendung von Building Information Modeling (BIM) im Facility Management (FM) der Chemie- und Pharmaindustrie in Deutschland.

BIM wird inzwischen vermehrt in Bauprojekten angewandt. Hierbei beschränkt sich die Anwendung meist auf die Planungs- und Bauphase. Darüber hinaus werden Anforderungen der Betriebsphase oft nicht in die Planungsphase einbezogen, obwohl in der Betriebsphase des Gebäudes ein Großteil der Lebenszykluskosten entsteht. Vor allem Daten und Informationen u.a. zum Gebäude selbst sowie zu verbauten Materialien und technischen Anlagen entstehen in der Planungsphase und sind essentiell für den Gebäudebetrieb. Um effizientere Abläufe im Lebenszyklus des Gebäudes zu ermöglichen, werden vermehrt Ansätze entwickelt, das digitale Gebäudemodell auch im FM anzuwenden. Bislang wurden allerdings keine einheitlichen Standards etabliert. Gemeinsam mit Projektpartnern aus der Industrie und dem FM wurden daher Informationsanforderungen für das BIM in der Chemie- und Pharmaindustrie aus Sicht des FM abgeleitet.
Dolor Anal Psicógeno- DAP: Un Nuevo Concepto de la Proctalgia Crónica
Authors: Pérez Matamoros Guillermo Gil , Pumagualle López Xavier Miguel , Pérez Chagerben Guillermo , Vega Díaz Andrés Santiago , Carrera González Joel David 
Published: April 2024

Introducción: El Dolor Anal Crónico cuando su causa no es orgánica, los criterios de Roma IV, lo definen como Dolor Anal Funcional Inespecífico, estos pacientes en su mayoría tienen trastornos psicológicos de base que los convierte como posibles factores causantes del dolor. Objetivos: Verificar prevalencia y determinar la asociación entre los factores psicológicos y el dolor anal crónico. Materiales y Métodos: Se trata de un estudio prospectivo, observacional, longitudinal, de cohorte y multicéntrico. Con un universo de 3.361 pacientes; excluidos 3.105, y una muestra obtenida de 256, no encontrando patología orgánica identificable. Resultados: La prevalencia de Dolor Anal Psicógeno fue de 256 (8%). Al tacto rectal identificamos dos variedades o subtipos: Variedad I, 85 pacientes (2.7%), con esfínter anal normotónico relacionado con Síndrome de Intestino Irritable. Variedad II, 171 pacientes (5.3%), con esfínter anal hipertónico relacionado con causas psicológicas puras. Riesgo Relativo (IC 95%) de los factores psicógenos ante el Dolor Anal Crónico de 8,06, con un 706% de incremento del riesgo para los pacientes expuestos al factor. El rango de edad predominante es de 41 a 50 años con 36% (n=93) y con mayor frecuencia en el sexo femenino con 54% (n=139). Conclusiones: Consideramos que la asistencia de la terapia farmacológica puede ser útil como eficiente placebo y sostenemos que las medidas invasivas, como: acupuntura, electroestimulación galvánica, bioretroalimentacion, entre otros imbrican para otra entidad nosológica. Al comprobar que, 5.3% de pacientes respondieron favorablemente al tratamiento psicológico, hay la posibilidad de estar frente a un nuevo enfoque diagnóstico y terapéutico.
Revision of the genus Lechytia Balzan, 1892 (Pseudoscorpiones, Chthoniidae) from China, with descriptions of two new species
Authors: Sun Jianzhou , Guo Xiangbo , Zhang Feng 
Published: April 2024

The hoffi species-group previously comprised only two species, Lechytia hoffi Muchmore, 1975 and Lechytia yulongensis Zhang and Zhang, 2014, of which L. yulongensis is distributed in China.
Three species of the genus Lechytia are described from China: Lechytia acutidentata sp. nov. and Lechytia depressidentata sp. nov. from Xizang Autonomous Region and L. yulongensis from Yunnan Province. The female of L. yulongensis is reported for the first time. In addition, a key to the hoffi species-group is provided.
Expérience et intensité du télétravail : quels liens avec le bien-être après une année de crise sanitaire en France?
Authors: Reboul Elena , Pailhé Ariane , Counil Émilie , l’équipe EpiCov  
Published: April 2024

Mobilisé massivement pendant la pandémie de Covid-19, le télétravail est désormais une forme installée d’organisation du travail ; or ses effets sur le bien-être des travailleurs et travailleuses restent ambivalents et débattus. S’appuyant sur une enquête longitudinale représentative de la population française (EpiCov), cet article retrace, au moyen d’une analyse de séquences, les trajectoires d’activité de près de 40 000 actifs occupés et, en particulier, l’usage du télétravail pendant la première année de crise sanitaire en France. Il examine ensuite, au moyen de régressions, ses répercussions sur l’articulation vie personnelle/vie professionnelle et la santé mentale dans une période d’accalmie (été 2021) permettant de se rapprocher des conditions de travail habituelles. Dans ce contexte, le télétravail apparaît comme un vecteur fort d’amélioration de l’articulation entre vie personnelle et vie professionnelle, et ce d’autant plus que le nombre de jours télétravaillés est élevé. Ce bénéfice est plus marqué pour les femmes et les parents, et indépendant de l’expérience du télétravail pré-pandémie. Le télétravail ne semble pas, en moyenne, affecter la dépression et les troubles anxieux.
Loi 25 : la frugalité a bien meilleur goût
Authors: Johnson Maxime 
Published: April 2024

Même si son objectif est d’abord et avant tout de protéger les renseignements personnels des Québécois, la Loi modernisant des dispositions législatives en matière de protection des renseignements personnels (Loi 25) risque d’avoir un autre effet sur les entreprises d’ici : diminuer leur boulimie numérique.
Les médias audiovisuels, l’autre vitrine de la création et des créateurs de mode
Authors: Santis Tiziana de , Poels Géraldine 
Published: April 2024

L’histoire et l’économie de la mode sont si liées à celles des médias qu’il est difficile de ne pas prendre en compte ces derniers dans l’inventaire de son patrimoine. Les collections de l’Institut national de l’audiovisuel (INA), en particulier, constituent une ressource originale et sous-estimée – même si de grandes maisons les mobilisent, désormais, pour ancrer leur communication dans leur histoire. En effet, si la mode est d’abord, dans les années 1950, identifiée comme un sujet de prédilection pour des « magazines féminins » ancrés dans l’assignation des femmes au foyer et aux tâches ménagères, des productrices audacieuses défendent bientôt l’idée qu’elle se prête au contraire à l’inventivité formelle et au recours à un ton décalé – donnant notamment naissance à la célèbre émission Dim Dam Dom (1965-1971), de Daisy de Galard. Les années 1990 représentent un second moment de rencontre entre la mode et le petit écran, moins marqué par la recherche d’expérimentations formelles dans la réalisation, mais qui voit naître, avec la diversification des chaînes, une floraison d’émissions consacrées au sujet, ainsi que les figures de chroniqueuses et d’émissions contribuant à construire l’identité des nouvelles chaînes privées, comme Mademoiselle Agnès ou Daphné Bürki sur Canal +, ou Paris Modes sur Paris Première. Cette contribution se propose de mettre en évidence ce que les archives audiovisuelles apportent à l’histoire de la mode, tout en soulignant les interactions entre la création textile et la création télévisuelle.
Cartographier le patrimoine vestimentaire et textile en France pour mieux le définir
Authors: Roy Sylvie , Kurkdjian Sophie 
Published: April 2024

Cet article entend revenir sur la genèse du projet de cartographie des collections textiles et vestimentaires mise en ligne sur le site de Culture(s) de Mode et dont l’origine est le rapport demandé par la ministre de la Culture, Audrey Azoulay, à Olivier Saillard en 2016-2017. Le réseau Culture(s) de Mode, créé en 2018 avec le soutien du bureau des Industries créatives du ministère de la Culture, a pris le relais en entreprenant un projet d’actualisation et d’élargissement de cette étude. Le choix s’est porté sur la réalisation d’une cartographie des fonds textiles et vestimentaires pour valoriser à la fois l’histoire des savoir-faire associés aux territoires et le développement des collections au sein des institutions. Cette étude décrit la mise en place d’un dispositif d’enquête diffusé au sein des directions régionales des Affaires culturelles (Drac) qui ont favorisé le contact avec différents musées spécialisés ou non dans la discipline étudiée. La (re)découverte de fonds spécifiques a renouvelé la compréhension de ce patrimoine tout en redéfinissant profondément son périmètre. Vitrine des collections publiques et privées, accessible à tous, la cartographie illustrée et interactive, offre différents niveaux de lecture permettant de croiser les données, de comparer les types de patrimoines, de comprendre l’histoire des collections muséales ou privées, de découvrir la richesse des thèmes des expositions, enfin elle constitue un premier réseau au service des chercheurs, des étudiants et du grand public. À travers quatre exemples ciblés, l’article s’attache à décrire des collections dont la présence inattendue dans les musées non spécialisés interroge notre perception des objets et des informations qu’ils délivrent. Pour conclure, cette contribution présente les projets que la cartographie a pu impulser et vise à montrer l’intérêt de poursuivre le développement d’un réseau dynamique autour des acteurs du patrimoine de la mode en France.
Feature by feature. Faire avec portraiture
Authors: Deschamps Catherine , Overney Laetitia , Proth Bruno 
Published: April 2024

An individual can both portray and be portrayed, that is, as the portrayer, producing, directing, editing the photograph; as the subject and recipient of portraiture, analyzing it, making it its own, even rejecting it. Our relationship with portraiture has become both ordinary and expansive, unattached to a particular discipline, comprising a complete experience in synchronic harmony between object and subject. Without going as far as erecting modern portraiture as a field (champ constitué), the present paper explores the broad and, sometimes, contradictory approach of portraits, in their visual or textual forms. They can draw from social sciences, offer alternative perspectives and occasionally assist in conveying subtleties and nuances that what would otherwise be challenging to transmit. This introduction aims to examine some socio-historical constants of portraiture, as well as its contemporary changes and variations. It seeks to pay attention to who or what is deemed worthy of being portrayed, the reasons for such selection, and the mediations that come into play.
RELATO DE EXPERIÊNCIA DO PROGRAMA DE RESIDÊNCIA PEDAGÓGICA (PRP): SUA IMPORTÂNCIA NA FORMAÇÃO DE FUTUROS PROFESSORES DE BIOLOGIA
Authors: Torres de Medeiros Marcelo henrique 
Published: April 2024

RESUMO:
O presente trabalho apresenta a importância do Programa de Residência Pedagógica (PRP) na formação de futuros professores de biologia e relato de experiência na docência do ensino médio. Destacando o papel do estágio na preparação dos alunos para a realidade da sala de aula e vê o PRP como uma solução para os desafios da docência. O PRP é apresentado como uma oportunidade para os alunos de ensino superior se imergirem na prática escolar, conectando a teoria à prática pedagógica. Destacando o uso de estratégias para promover a aprendizagem significativa e a importância da interação entre professor e aluno.

Palavras-Chave: estágio; licenciatura; ensinar ciência;
Prehospital Factors Associated with Delayed Hospital Arrival of Stroke Patients: A Regional Single-Center Study from India
Authors: Edakkattil Sachin , Abraham Siju V. , Panattil Neenu J. , Gafoor Faris A. , Jacob Leenus , Liu Renyu 
Published: April 2024

Background:
Only a small percentage of patients with acute stroke are currently eligible for thrombolysis, partly due to severe delays in hospital arrival. We had previously conducted the first regional study to assess the factors delaying acute stroke care in India. The present study aims to understand and describe in depth the variables associated with prehospital delay among patients admitted with an acute ischemic stroke.

Methods:
Data were prospectively collected by conducting an in-depth interview of 470 acute ischemic stroke patients and their bystanders, aged above 18 years, presenting to the Department of Emergency Medicine, Jubilee Mission Medical College and Research Institute, Thrissur. Patients who arrived within 4.5 h of symptom onset were considered as “early arrival” and those who arrived after 4.5 h were considered as “delayed arrival.” Univariate and multivariate analyses were undertaken to determine associations between variables of interest and delays to hospital presentation.

Results:
Of the 470 patients who met the inclusion criteria, 73 patients reached within 4.5 h (15.5%), whereas 397 patients arrived after 4.5 h. The mean age of acute stroke patients who reached within 4.5 h was 63 ± 13.7 years, whereas the mean age of those who reached after 4.5 h was 63 ± 12.1 years. Binary logistic regression performed to quantify the associations of prehospital factors showed an increased risk of prehospital delay among individuals with lack of awareness (odds ratio [OR] = 5.16 [3.040–8.757], P < 0.001), followed by those for whom a vehicle was not available at the site of event (OR = 3.745 [1.864–7.522], P < 0.001). Within the predefined socioeconomic strata, compared to lower class, upper middle class had less risk (OR = 0.135 [0.018–1.035], P = 0.054), whereas the distance from first medical contact to emergency department contributed moderate risk (OR = 1.071 [1.028–1.116], P < 0.001) for prehospital delay.

Conclusions:
Health promotion techniques that increase public knowledge about the early signs of stroke, transferring patients directly to hospitals with thrombolysis capabilities, and making ambulance services more widely available are appropriate measures to reduce prehospital delay.
Treatment of Condylar Hypoplasia in Alagille Syndrome - A Case Report
Authors: Nardini Luca Guarda , Val Matteo , Colonna Anna , Cagidiaco Edoardo Ferrari , Ferrari Marco , Manfredini Daniele 
Published: April 2024

Abstract

Rationale:
Alagille syndrome is a rare genetic disorder with dental and facial abnormalities in the head-and-neck area. It is autosomal dominant and occurs in approximately 1 in 100,000 people. No cases of Alagille Syndrome (ALGS) with mandibular hypoplasia and temporomandibular joint ankyloses (TMJa) have been reported to date.

Patient Concerns and Diagnosis:
A 3-year-old female patient suffering from ALGS came to our hospital affected by unilateral mandibular hypoplasia and TMJa with severe limitation of mouth opening (maximal interincisal distance [MID] of 2 mm).

Treatment:
A two-phase surgical management approach was undertaken based on computed tomography scans and the patient’s age. The first phase involved mandibular distraction, followed by arthroplasty with amniotic human membrane placement.

Outcomes:
After immediate post-surgery rehabilitation, the patient showed good mandibular function with no complications after 15 months. MID was 20 mm.

Take-away Lessons:
This is a rare and interesting case with no previous literature reports. The use of amniotic membranes in surgical management adds further significance.
Comparison of TAScope (an Indigenous Videolaryngoscope) with McGrath MAC®: A Manikin Study
Authors: Anandaswamy Tejesh C , Sultana Shama , Shivakumar Sonika , Manegar Rachana N , Gangadkar Siri , Patil Gagandeep R 
Published: April 2024

Background:
Videolaryngoscopes are an important advancement in airway management. They are now commercially available in various designs and sizes, but are expensive. The Anaesthetist Society scope videolaryngoscope (TAScope) is an indigenously designed videolaryngoscope by a member of the anaesthesia fraternity and is economical. Before being adopted for clinical use, it is appropriate to study it rigorously. The objective of the present study was to compare the TAScope with the McGrath MAC® videolaryngoscope for time to successful intubation in an adult manikin.

Methods:
The present study was conducted on an adult intubation training manikin. The sequence of the use of either videolaryngoscope was chosen randomly by a computer-generated random sequence. The following parameters were noted: time of successful intubation, time required to obtain glottic view, glottic view obtained in terms of Cormack–Lehane grade and percentage of glottic opening score and number of attempts at intubation. Statistical analysis was done using SPSS version 23.

Results:
All intubations were successful with both videolaryngoscopes. The time for successful intubation was significantly faster with McGrath MAC® (18.31 ± 1.53 s) compared to TAScope (27.21 ± 3.03 s) (P < 0.001). The time to obtain a glottic view was slightly shorter with TAScope (6.25 ± 1.78 s) compared to McGrath MAC® (6.66 ± 1.15 s).

Conclusion:
The time for intubation was longer with TAScope but with a similar glottic view and intubation success compared to McGrath videolaryngoscope.
The relation between hepatitis C viral infection and follicular lymphoma clinical course and outcome in a single-center study
Authors: Shaaban Yasmine , El-Ashwah Shaimaa , Ghoneem Elsayed A , Eladel Ahmed , Mohsen Asmaa 
Published: April 2024

Background
Hepatitis C virus (HCV) infection has been related in the etiology of many lymphomas. Follicular lymphoma (FL) is the most common subtype of indolent non-Hodgkin lymphoma. This comparative retrospective study aimed to identify a relationship between HCV and FL clinicopathologic features and neoplasm outcome.

Patients and methods
This study was conducted on 103 patients with FL who attended our institution during 2008–2019.

Results
The prevalence of patients with HCV FL was 49.5% and showed significant B symptoms (P=0.023), advanced stages (P=0.016) with higher Follicular Lymphoma International Prognostic Index scores (P=0.042).
Progression-free survival showed no differences regarding the viral infection or histological grades. Median overall survival showed significant improvement with histological grades 1–2 (P<0.0001), low Follicular Lymphoma International Prognostic Index, and HCV negative patients with FL, especially in the younger subgroup.

Conclusion
HCV positive patients with FL had a significantly more aggressive clinicopathological presentation and shorter overall survival. Thus, early virology screening and eradication of HCV infection in FL patients may improve the neoplasm course.
Predictors of outcome of trace element levels in acute myeloid leukaemia patients: a prospective study for one year
Authors: Mohammed Mohammed A-E 
Published: April 2024

Abstract

Background
Trace elements are essential for mammalian metabolism. To date, no data have been presented predicting the relapse-free survival of acute myeloid leukemia (AML) patients based on the level of trace elements in the serum.
This prospective cohort study had the following objectives: (i) to quantify essential trace elements in the serum of AML patients.(ii) to examine the predictive values of the trace element levels in newly diagnosed de novo AML patients.

Methods
50 patients AML were studied. The control group consisted of 50 patients. Serum levels of the trace elements copper, zinc, copper to zinc ratio and selenium, were measured by spectrophotometry. The associations of trace element with the relapse-free survival of these AML patients were assessed by Kaplan–Meier survival curves.

Results
AML patients, a control group, and AML subgroups with and without hematological relapse were evaluated for trace element concentrations. AML patients showed higher copper and lower zinc levels than controls. AML patients had increased Cu/Zn ratios. AML patients had reduced selenium levels. Relapsed AML patients had increased copper and Cu to Zn ratios, but decreased zinc and selenium. Copper, zinc, Cu to Zn ratio, and selenium cut-off values for AML relapse and nonrelapse were identified via ROC curve analysis. Kaplan-Meier curves showed that patients with higher copper, lower zinc, higher Cu to Zn ratio, or lower selenium had a shorter estimated mean relapse-free survival time.

Conclusions
Trace element levels are correlated with long-term relapse-free survival in newly diagnosed AML patients and may serve as predictive biomarkers.