bluuebunny/crossref_metadata_2025_split huggingface dataset:
A Novel Ternary Pseudocapacitive Electrode with Synergistic Contributions
Authors: Zhou Yang , Tynan Benjamin , Dai Liming , Rider Andrew N. , Wang Chun H. 
Published: March 2024

AbstractTernary electrodes represent an exciting strategy to substantially enhance the performance of supercapacitors beyond what binary electrodes offer. However, the interplays among ternary constituents and their possible synergies remain poorly understood. This study investigates a ternary electrode design, wherein ferric oxyhydroxide (FeOOH) and magnesium dioxide (MnO2) are co‐deposited onto carbon nanotube (CNT) mats. The results reveal that the ternary electrode demonstrates a 33.3% reduction in internal resistance and a 59% increase in areal capacitance compared to its binary MnO2/CNT counterpart. Furthermore, the ternary electrode achieves a 25% increase in capacitance compared to the combined capacitances of separate MnO2/CNT and FeOOH/CNT electrodes. These findings demonstrate that combining FeOOH and MnO2 can synergistically enhance electrical conductivity and pseudocapacitance beyond their binary counterparts. This design yields a surface capacitance exceeding 3500 mF cm−2 at an active material loading up to 15 mg cm−2. By pairing with a binary FeOOH/CNT electrode, the resulting asymmetric supercapacitor exhibits an operational voltage window to 1.6 V. To demonstrate the potential of the new design, ternary electrodes are integrated into wearable and structural supercapacitors. The new synergistic ternary electrode approach provides a promising avenue for enhancing energy storage capacitance and expanding the scope of energy storage structure applications.
Ionic Liquid‐Induced 1D Perovskite: Exploring 1D Perovskite Structure to 1D/3D Heterojunction‐Based Photovoltaics
Authors: Wang Fei , Zhou Kang , Zhou Chao , Liang Xiao , Wang Taomiao , Sun Yonggui , Li Yongjun , Li Qiannan , Zhou Xianfang , Yang Guo , Duan Dawei , Zhu Jiajie , Zhu Quanyao , Lin Haoran , Shi Yumeng , Yang Chunming , Xing Guichuan , Hu Hanlin 
Published: March 2024

AbstractThe synergistic utilization of low‐dimensional perovskites with 3D perovskite architectures represents a pervasive approach for fabrication of high‐performance and enduring perovskite solar cells (PSCs). In this work, four distinct ionic liquids (ILs) with distinct cations, were introduced on the surface of 3D perovskite to induce the formation of 1D perovskite.Starting with the analysis of 1D/3D heterojunction structures, the assessment foucsed on the binding energies in four ILs‐induced 1D/3D heterojunctions, comparing electron cloud density within 1D/3D structures, and calculating the formation energies associated with iodine and lead defects within these four 1D/3D perovskite structures via DFT calculations. Furthermore, the time‐resolved grazing‐incidence wide‐angle X‐ray scattering technique, as employed in this study, offers real‐time insights into the phase‐transition occurring during the process of ILs coating and the formation of 1D/3D heterojunctions. The well‐designed and optimized 1D perovskite layer significantly reduces the residual lead iodide (PbI2), modulates the work function of the perovskite, and passivates defects in the 3D perovskite, thereby reducing non‐radiative recombination and enhancing charge transport. With the assistance of 1D/3D hybrid films, we achieved an exceptional power conversion efficiency (PCE) of 24.75% in the generated PSCs with remarkable stability.
Randomized, controlled, multi‐center phase II study of postoperative enoxaparin treatment for venous thromboembolism prophylaxis in patients undergoing surgery for hepatobiliary‐pancreatic malignancies
Authors: Shinke Go , Takeda Yutaka , Ohmura Yoshiaki , Kobayashi Shogo , Wada Hiroshi , Morimoto Osakuni , Tomokuni Akira , Shimizu Junzo , Asaoka Tadafumi , Tanemura Masahiro , Noda Takehiro , Doki Yuichiro , Eguchi Hidetoshi 
Published: March 2024

AbstractPurposePostoperative venous thromboembolism (VTE) risk is pronounced after abdominal cancer surgery. Enoxaparin shows promise in preventing VTE in gastrointestinal, gynecological, and urological cancers, but its application after surgery for hepatobiliary‐pancreatic malignancy has been under‐evaluated due to bleeding concerns. We confirmed the safety of enoxaparin administration in patients undergoing curative hepatobiliary‐pancreatic surgery for malignancies in a prospective, multi‐center, phase I study.MethodsThe study was conducted from April 2015 to May 2021 across eight specialized centers. Patients (n = 262) were randomized to enoxaparin prophylaxis given postoperatively for 8 days (n = 131) or control (n = 131). The primary endpoint was the efficacy in reducing VTE. Secondary endpoints examined safety.ResultsThe full analysis set included 259 patients (131 control, 129 enoxaparin). The per‐protocol population included 233 patients (117 control, 116 enoxaparin). Most cases were hepatic malignancies (111 control, 111 enoxaparin). The median administration duration of enoxaparin was 7 days, with 92% receiving 4000 units/day. Despite a reduction in the relative risk (RR) of VTE due to postoperative enoxaparin administration, the results were not significant (control: four cases, 3.4% vs. treatment: two cases, 1.7%; RR 0.50, 95% CI 0.09–2.70; p = 0.6834). No significant difference was found in the incidence of bleeding events (control: five cases, 4.3% vs. treatment: five cases, 4.3%, RR 1.00, 95% CI 0.53–1.89; p = 1.0000).ConclusionsThe perioperative administration of enoxaparin in hepatobiliary‐pancreatic malignancies is feasible and safe. However, further case accumulation and investigation are necessary to assess its potential in reducing the occurrence of VTE.
Behavioral and transcriptomic analyses of mecp2 function in zebrafish
Authors: Santistevan Nicholas J. , Ford Colby T. , Gilsdorf Cole S. , Grinblat Yevgenya 
Published: March 2024

AbstractRett syndrome (RTT), a human neurodevelopmental disorder characterized by severe cognitive and motor impairments, is caused by dysfunction of the conserved transcriptional regulator Methyl‐CpG‐binding protein 2 (MECP2). Genetic analyses in mouse Mecp2 mutants, which exhibit key features of human RTT, have been essential for deciphering the mechanisms of MeCP2 function; nonetheless, our understanding of these complex mechanisms is incomplete. Zebrafish mecp2 mutants exhibit mild behavioral deficits but have not been analyzed in depth. Here, we combine transcriptomic and behavioral assays to assess baseline and stimulus‐evoked motor responses and sensory filtering in zebrafish mecp2 mutants from 5 to 7 days post‐fertilization (dpf). We show that zebrafish mecp2 function is required for normal thigmotaxis but is dispensable for gross movement, acoustic startle response, and sensory filtering (habituation and sensorimotor gating), and reveal a previously unknown role for mecp2 in behavioral responses to visual stimuli. RNA‐seq analysis identified a large gene set that requires mecp2 function for correct transcription at 4 dpf, and pathway analysis revealed several pathways that require MeCP2 function in both zebrafish and mammals. These findings show that MeCP2's function as a transcriptional regulator is conserved across vertebrates and supports using zebrafish to complement mouse modeling in elucidating these conserved mechanisms.
Ultrathick MA2N4(M'N) Intercalated Monolayers with Sublayer‐Protected Fermi Surface Conduction States: Interconnect and Metal Contact Applications
Authors: Tho Che Chen , Feng Xukun , Cao Liemao , Wang Guangzhao , Liang Shi‐Jun , Lau Chit Siong , Guo San‐Dong , Ang Yee Sin 
Published: March 2024

AbstractRecent discovery of ultrathick MoSi2N4(MoN)n monolayers open up an exciting platform to engineer two‐dimensional (2D) material properties via intercalation architecture. In this study, a series of ultrathick MA2N4(M'N) monolayers (M, M' = Mo, W; A = Si, Ge) is computationally investigated under both homolayer and heterolayer intercalation architectures, in which the same and different species of transition metal nitride inner core sublayer are intercalated by outer passivating nitride sublayers, respectively. The MA2N4(M'N) are stable metallic monolayers with excellent mechanical strength. Intriguingly, the metallic states around Fermi level are localized within the inner core sublayer. Carrier conduction mediated by electronic states around the Fermi level is thus spatially insulated from the external environment by the native outer nitride sublayers, suggesting the potential of MA2N4(M'N) in back‐end‐of‐line metal interconnect applications. N and Si (or Ge) vacancy defects at the outer sublayers create ‘punch through’ states around the Fermi level that bridges the carrier conduction in the inner core sublayer and the outer environment, forming an electrical contact akin to the ‘via' structures of metal interconnects. It is further shown that MoSi2N4(MoN) can serve as a quasi‐Ohmic contact to 2D WSe2. These findings reveal the potential of ultrathick MA2N4(MN) monolayers in interconnect and metal contact applications.
Dual substitution of host lattice ions to enhance the luminescence properties of Zn2TiO4:Cr3+ phosphor
Authors: Cheng Kang , Huang Weichao , Gong Xinyong , Deng Chaoyong 
Published: March 2024

AbstractNear‐infrared light sources have potential applications in many fields. Cr3+ is a good luminescence centre to prepare near‐infrared phosphors. Improving the performance of existing near‐infrared luminescent materials has indeed attracted great interest from researchers. The luminescence properties of Zn2TiO4:Cr3+ were improved by crystal field engineering strategies. Zn2+–Ti4+ was partially replaced using a Li+–Nb5+ ion pair based on the Zn2TiO4:Cr3+ phosphors. Luminescence Cr3+‐activated luminescent materials are sensitive to changes in the local crystal structure and crystal field environment. Doping of Li+–Nb5+ increased the luminescence intensity up to 2.7 times that of the undoped sample. Also, the thermal stability of the phosphor was greatly increased by the replacement of Li+–Nb5+.
Development and internal validation of a nomogram based on peripheral blood inflammatory markers for predicting prognosis in nasopharyngeal carcinoma
Authors: Lai Jing , Lin Peixin , Zhuang Jiafeng , Xie Zhiwei , Zhou Hechao , Yang Donghong , Chen Zihong , Jiang Danxian , Huang Jing 
Published: March 2024

AbstractBackgroundInflammatory markers, including the product of neutrophil count, platelet count, and monocyte count divided by lymphocyte count (PIV) and the platelet‐to‐white blood cell ratio (PWR), have not been previously reported as prognostic factors in nasopharyngeal carcinoma (NPC) patients. In order to predict overall survival (OS) in NPC patients, our goal was to create and internally evaluate a nomogram based on inflammatory markers (PIV, PWR).MethodsA retrospective study was done on patients who received an NPC diagnosis between January 2015 and December 2018. After identifying independent prognostic indicators linked to OS using Cox proportional hazards regression analysis, we created a nomogram with the factors we had chosen.ResultsA total of 630 NPC patients in all were split into training (n = 441) and validation sets (n = 189) after being enrolled in a population‐based study in 2015–2018 and monitored for a median of 5.9 years. In the training set, the age, PIV, and PWR, selected as independent predictors for OS via multivariate Cox's regression model, were chosen to develop a nomogram. Both training and validation cohorts had C‐indices of 0.850 (95% confidence interval [CI]: 0.768–0.849) and 0.851 (95% CI: 0.765–0.877). Furthermore, compared with traditional TNM staging, our nomogram demonstrated greater accuracy in predicting patient outcomes. The risk stratification model derived from our prediction model may facilitate personalized treatment strategies for NPC patients.ConclusionOur findings confirmed the prognostic significance of the PWR and PIV in NPC. High PIV levels (>363.47) and low PWR (≤36.42) values are associated with worse OS in NPC patients.
Replication of relations among working alliance, distress and attendance variables
Authors: Meier Scott T. 
Published: March 2024

AbstractIntroductionRecent reports from the World Health Organization and the American Psychological Association have highlighted the gap between the growing need for mental health services and available resources. Even with additional funding, however, the high proportion of clients who drop out after only a few sessions presents a significant obstacle to providing effective help.MethodsUsing archival data from the Research Consortium of Counseling and Psychological Services in Higher Education, this study examined relations between client attendance and two constructs of the early therapeutic environment model, working alliance and client distress.ResultsSession count evidenced a floor effect, with the mean of the distribution (4.45) <1 standard deviation (SD; 4.11) from the lowest possible score. In contrast, clients' alliance scores (measured with the Working Alliance Inventory) displayed a ceiling effect, with the mean 1.48 SD units from the highest possible score. Analyses indicated that alliance and distress (measured via the Outcome Questionnaire—45) scores exhibit different nonlinear relations with session count. Working alliance scores exhibited a power function indicating that rapid increases in alliance scores during initial sessions were associated with larger session counts. In contrast, distress scores formed a funnel shape with session count such that moderate initial distress was associated with greater attendance. Clients whose alliance scores evidenced a ceiling effect accounted for most of the observed change on the distress measure.ConclusionTo enhance attendance, study findings suggest that, as early as possible, therapists should maximise the client–therapist alliance and moderate the level of client distress.
Hospital racial composition and outcomes after transcatheter and surgical aortic valve replacement
Authors: Biancari Fausto , Mäkikallio Timo 
Published: March 2024

Key points
Racial/ethnic cardiovascular disparities have been demonstrated in optimal cardiovascular health.
Racial residential segregation may be a cause of disparities in health.
Early outcomes after aortic valve replacement are worse in hospitals treating a larger proportion of non‐White patients.
Cooperative Cu with defective MXene for enhanced nitrate electroreduction to ammonia
Authors: Tan Yi , Zhao Yijin , Chen Xiaokang , Zhai Shengliang , Wang Xiao , Su Le , Yang Hongyan , Deng Wei‐Qiao , Ho Ghim Wei , Wu Hao 
Published: March 2024

AbstractThe electroreduction of nitrate (NO3RR) to ammonia (NH3) provides a promising solution to enable environmental remediation caused by ‐containing waste and also allows for energy‐saving NH3 generation. Adsorption of *NO2 intermediate may be strengthened to decrease byproducts (e.g., ) and favor the eight‐electron NO3RR into NH3. In this work, copper‐incorporated O‐vacancy containing Ti3C2 MXene (Cu@Ti3C2Ov) is reported, which cooperatively inhibits production and facilitates hydrogenation, leading to approximately 100% Faradaic efficiencies of NH3 and high yield rates at various potentials. Density functional theory calculations show that and the *NO2 intermediates have a significant interaction with the Cu@Ti3C2Ov catalyst. Moreover, the formation of has a high energy barrier, which explains the appealing catalytic performance of the Cu@Ti3C2Ov toward NO3RR with suppressed and elevated NH3 selectivity. This work would motivate the prudent design of new catalysts for high‐performance NO3RR to NH3 by elucidating the significance of stabilizing the *NO2 intermediate.
Polymorphism in F pocket affects peptide selection and stability of type 1 diabetes‐associated HLA‐B39 allotypes
Authors: Amarajeewa A. W. Peshala , Özcan Aslihan , Mukhtiar Alveena , Ren Xu , Wang Qianyu , Ozbek Pemra , Garstka Malgorzata A. , Serçinoğlu Onur 
Published: March 2024

AbstractHLA‐B*39:06, HLA‐B*39:01, and HLA‐B*38:01 are closely related HLA allotypes differentially associated with type 1 diabetes (T1D) risk and progression. B*39:06 is highly predisposing, while B*39:01 and B*38:01 are weakly predisposing and protective allotypes, respectively. Here, we aimed to decipher molecular mechanisms underlying the differential association of these allotypes with T1D pathogenesis. We addressed peptide binding and conformational stability of HLA‐B allotypes using computational and experimental approaches. Computationally, we found that B*39:06 and B*39:01 allotypes had more rigid peptide‐binding grooves and were more promiscuous in binding peptides than B*38:01. Peptidomes of B*39:06 and B*39:01 contained fewer strong binders and were of lower affinity than that of B*38:01. Experimentally, we demonstrated that B*39:06 and B*39:01 had a higher capacity to bind peptides and exit to the cell surface but lower surface levels and were degraded faster than B*38:01. In summary, we propose that promiscuous B*39:06 and B*39:01 may bind suboptimal peptides and transport them the cell surface, where such unstable complexes may contribute to the pathogenesis of T1D.
Base‐ and Visible‐Light‐Promoted Formation of 3‐Benzyl‐3‐Methoxyisoindolin‐1‐one
Authors: Martin Nathan , Moncomble Aurélien , Pélinski Lydie , Deniau Eric , Bousquet Till 
Published: March 2024

AbstractAryl diazonium salts are versatile compounds known for their reactivity in various transformations. In this study, we explored the arylation of 3‐methylene isoindolinones using aryl diazonium salts. The objective was to develop a method for accessing 3‐benzyl‐3‐methoxyisoindolin‐1‐ones, a class of compounds with diverse biological activities and synthetic importance. Optimization of the reaction conditions revealed the significance of light irradiation for improved yields. The substrate scope investigation demonstrated the compatibility of various diazonium salts and N‐substituents on the 3‐methylene isoindolinone scaffold, yielding the corresponding methoxy lactams with high yields. Mechanistic insights were obtained by observing the effect of base and light irradiation. Two initiation mechanisms were proposed: in the presence of a base, the reaction could proceed even without light irradiation, while light irradiation was necessary in the absence of a base. DFT calculations were performed to elucidate the mechanism of the reaction and provide energetic considerations
About drying phenomena of fuel cell and electrolyzer CCM inks: Selectivity of the evaporation of 1‐propanol/water mixtures
Authors: Quarz Philipp , Zimmerer Nadine , Scharfer Philip , Schabel Wilhelm 
Published: March 2024

AbstractIn the production of catalyst‐coated membranes (CCMs) for proton‐exchange membrane fuel cells and electrolyzers, the ink formulation and its processing are key factors in determining the resulting catalyst layer. Catalyst inks often contain a multicomponent solvent mixture. Selective drying, which can occur with solvent mixtures, changes the composition in the solidifying film and thus influences the microstructure of the layer that forms. The selectivity depends on the material‐specific thermodynamics of the solvents and the process‐related drying parameters. Different 1‐propanol/water mixtures serve as the state of the art material system considered and commonly used for CCM inks. Typical solvent mixtures can be dried selectively or non‐selectively, depending on the initial ink composition and humidity of the drying air. In mixtures that contain more 1‐propanol than the azeotropic or arheotropic composition, the 1‐propanol content accumulates in the remaining liquid; if there is less, it decreases. Increasing the preloading of the drying air with water leads to a relative water enrichment and shifts the tipping point to higher initial alcohol fractions. This behavior can be transferred to the real CCM production.
‘We're at war.’ Healthcare workers’ experience with organisational change, uncertainty and vaccine hesitancy in 2021 and 2022 during the COVID‐19 vaccination programe in Poland
Authors: Wróblewski Michał , Stankowska Joanna , Kawiak‐Jawor Ewa 
Published: March 2024

AbstractThis article analyses the organisation of the mass COVID‐19 vaccination programme in Poland and its consequences for various aspects of the social identity of healthcare workers (HCWs). Based on 31 in‐depth interviews with HCWs, our study reveals the following: (1) Certain elements of the programme (inclusion of other healthcare professionals like pharmacists and laboratory diagnosticians as vaccinators) and the provision of additional infrastructure (pharmacies and shopping malls) may prompt scepticism and criticism in physicians and nurses who feel challenged about their professional autonomy and hierarchies; (2) Given the high levels of professional uncertainty, the implementation of the COVID‐19 vaccination is forcing HCWs to revise their attitude to medical standards, resulting in specific responses and adaptation strategies (ranging from the active involvement in the programme due to the sense of mission, to more or less evident scepticism); and (3) Confronting vaccine hesitancy, both among patients and other HCWs, contributes to the feeling of helplessness, leading to criticism of policymakers.
Could tranexamic acid be a suitable alternative to cryotherapy for symptomatic cervical ectopy? Results from a randomized clinical trial
Authors: Tofighi Shabnam , Hekmatfar Farzaneh , Tavakolizadeh Mahdi , Garrosi Lida , Gholami Hamideh , Haghighi Maryam 
Published: March 2024

AbstractObjectiveCervical ectropion occurs due to the eversion of the endocervix that exposes glandular cells to the vaginal milieu. The aim of the present study was to evaluate and compare the clinical efficacy of effervescent vaginal tablets of tranexamic acid and cryotherapy in women with symptomatic cervical ectopy.MethodsThe current randomized clinical trial was conducted on 92 samples of women with cervical erosive ectropion from March 20, 2022 to August 27, 2022. Participants were divided into two groups; the intervention group (n = 46) was treated with a 400 mg effervescent vaginal tablet of tranexamic acid and the control group (n = 46) underwent cryotherapy. All the patients were requested to visit weekly in the first month and then monthly for the next 3 months, and the outcomes encompass improvement of symptoms (leukorrhea, dyspareunia, pelvic pain, post‐coital bleeding, and suprapubic pain) and cervical erosive ectropion view were monitored based on repeated examinations.ResultsIn this study, no statistically significant difference was observed in cure rate of symptoms between study groups (P value > 0.05). Women in both the tranexamic acid and cryotherapy groups reported significant improvements in dyspareunia (34 [75%] vs 31 [67%]), pelvic pain (34 [75%] vs 34 [74%]), post‐coital bleeding (37 [81%] vs 31 [67%]), leukorrhea (36 [78%] vs 36 [78%]), suprapubic pain (32 [71%] vs 33 [73%]) disappearance of cervical ectropion tranexamic acid (40 [86%], vs 39 [84%]).ConclusionOur findings highlighted the equal effect of tranexamic acid and cryotherapy for treating cervical ectropion. Due to the ease of use, availability, and fewer side effects of tranexamic acid, it can be a suitable alternative to cryotherapy.Trial RegistrationIRCT20220115053719N1. The name of the registry: Iranian Registry of Clinical Trials. URL of registration: https://en.irct.ir/trial/61483.
Recovery from substance use disorder among adolescents: Roles of adverse and positive childhood experiences
Authors: Kim Isak , Park Yuhyun , Chasek Christine , Bjornsen Abby , Shin Kahyen 
Published: March 2024

AbstractThis study examines the roles of positive childhood experiences (PCEs) and adverse childhood experiences (ACEs) on the recovery from substance use disorder (SUD) among adolescents ages 12–17, utilizing data from the 2016–2019 National Survey of Children's Health (NSCH). On a sample of 256 adolescents who have had SUD, a hierarchical binary logistic regression analysis demonstrated that the cumulative PCEs significantly increased the odds of SUD recovery, whereas the cumulative ACEs did not decrease the odds.