bluuebunny/crossref_metadata_2025_split huggingface dataset:
Nutritional intervention during a teleprehabilitation pilot study in high-risk patients with colorectal cancer: adherence, motivators and barriers
Authors: Beukers K. , Franssen R. F.W. , Beijaard K. , de Wouw A. J. van , Havermans R. C. , Janssen-Heijnen M. L.G. 
Published: March 2024

Abstract

Purpose The preoperative period provides a window of opportunity to improve modifiable risk factors for treatment complications such as malnutrition, so-called prehabilitation. Identifying factors related to adherence to nutritional interventions is essential for optimizing prehabilitation programs. The aim of this study is to evaluate a nutritional support module as part of a teleprehabilitation program in high-risk patients with CRC.Methods A secondary analysis of the nutritional support module of a pre-post teleprehabilitation pilot study was performed. Change in weight, complaints with intake, motivation, and subjective and objective adherence were evaluated.Results Eleven patients were included. Subjectively, six patients were able to adhere to the nutritional advice, despite that nine of eleven patients experienced difficulties with the amount of food that was advised by the dietician. Six of eleven patients gained weight during the prehabilitation program. After prehabilitation, nine of eleven (82%) were able to reach 100% of their energy requirement and six of eleven (55%) were able to reach 100% of their protein requirement. Differences between patients in motivation and/or having complaints did not seem to be associated with protein and energy intake.Conclusion This secondary analysis of a pilot study provides insights into understanding patients’ experiences with a nutritional support module as part of a teleprehabilitation program. With 82% of patients who were able to reach 100% of their energy requirement, teleprehabilitation seems to be feasible, while there is still room for improvement with respect to protein intake as only 55% of patients reached a sufficient intake.
Optimal Control Analysis for the Nipah infection with constant and time-varying Vaccination and Treatment with real data application
Authors: Khan Muhammad Younas , Ullah Saif , Farooq Muhammad , Saqib Abdul Baseer 
Published: March 2024

Abstract

In the last two decades, Nipah virus (NiV) has become a significant paramyxovirus transmitted by bats, causing severe respiratory illness and encephalitis in humans. Due to the severity of the disease, its potential for human-to-human transmission, zoonotic characteristics , and the absence of approved therapeutic treatments, NiV has been included in the World Health Organization’s Blueprint list of priority pathogens. In this paper, a novel mathematical model is proposed to investigate the dynamics and optimal control of the NiV. The model incorporates two modes of transmission: human-to-human and food-borne. It also considers the impact of coming in contact with an infected corpse as a potential route for virus transmission. The NiV model is initially assessed with constant controls. The analysis identifies three equilibrium states: the NiV-free equilibrium, the infected flying foxes-free equilibrium, and the NiV-endemic equilibrium state. Furthermore, a theoretical analysis is conducted to ascertain the stability of both the Nipah virus-free equilibrium and the Nipah virus endemic equilibrium points of the model. In addition to enhance the biological importance of the study, the model is fitted to the reported cases in Bangladesh during 2001 to 2015 and the model parameters are estimated using standard nonlinear least square technique. A sensitivity analysis of the model-embedded parameters is conducted to derive the optimal time-dependent controls. An optimal control model is formulated using the sensitivity indices, and numerical simulations are employed to determine the most effective strategy for disease eradication. The model is optimized via optimal control theory coupled with well-established Pontryagin’s maximum principle utilized to achieve primary optimality simulation. Finally, simulation results are provided to verify the theoretical results.
Navigating PINNs via maximum residual-based continuous distribution
Authors: Wang Yanjie , Liu Feng , Wu Faguo , Zhang Xiao 
Published: March 2024

Abstract
Physics-informed neural networks (PINNs) constitute a powerful framework that seamlessly integrate neural networks with underlying physical principles through the physics-informed loss function. This framework proficiently addresses both forward and inverse problems of partial differential equations (PDEs), while encounters challenges in abrupt spatio-temporal domains and sharp solutions. The prevailing consensus underscores the importance of data quality in influencing the convergence rate, predictive accuracy and other performance metrics. Nevertheless, the generation and selection of high-quality training data remain an open problem. In this study, we devise a sampling-enhanced framework to unify existing sampling methods for PINNs from the perspective of deep Galerkin method. Furthermore, we propose MRD (\textbf{M}aximum \textbf{R}esidual-based continuous \textbf{D}istribution) to navigate PINNs and move training points towards the high-residual region. It not only extends existing residual-based adaptive sampling to a continuous form for more precise residual indication, but also effectively generates a high-quality training dataset. Our method is generic, straightforward, and easily extensible to any scenarios of PINNs. Experimental results across all four equations demonstrate a significant improvement relative to baselines, validating the generality and efficacy of our MRD method.
Mathematics Subject Classification (2020) 65M50 · 65C10 · 68T07
Comparative Analysis of Open and Closed Nasal Fractures in Trauma Settings: Mechanisms, Intent, Surgical Interventions, and Outcomes
Authors: Alnemare Ahmad K. 
Published: March 2024

Abstract
Background
Nasal fractures, one of the most common facial injuries in trauma settings, present diverse challenges in terms of diagnosis, management, and prognosis. Understanding the mechanisms of injury, intent, procedural interventions, and mortality outcomes is crucial to enhance patient care and develop preventive strategies. This study aimed to analyze the patterns and trends in nasal fractures, categorizing them by mechanism and intent, examining the range of procedural interventions, and assessing mortality rates. The goal was to provide a comprehensive understanding of nasal fractures in trauma settings to inform clinical practice and prevention efforts.
Methods
This retrospective analysis was conducted using trauma data from 2013 to 2016. Nasal fractures were classified into closed and open types and the mechanisms of injury were categorized. The intent behind the injury was also classified. Procedural interventions, including turbinectomies, septoplasties, and nasal fracture reduction, were compared between the two fracture types. Mortality rates were calculated and analyzed year-wise.
Results
This study analyzed 122,574 closed and 9,704 open nasal fractures to elucidate the demographic, hospital, procedural, and clinical characteristics. Significant risk factors for open nasal fractures included higher Injury Severity Score (OR 1.004 per point, 95% CI 1.002-1.006), self-inflicted intent (OR 2.157, 95% CI 1.855-2.509), unintentional causes (OR 2.166, 95% CI 1.964-2.388), and firearm mechanism (OR 8.839, 95% CI 7.287-10.722) compared to assault injuries. Open fractures underwent more operative interventions such as nasal fracture reduction and nasal plastic repair. Patients with closed fractures underwent more operations on the nose, mouth, and pharynx. Open fractures had longer median procedure times (18 vs. 8.4 h) but similar lengths of hospital stay.
Conclusions
Injury severity has emerged as a major predictor of open nasal fractures, with severe multi-trauma substantially increasing the risk. This national analysis informs prevention priorities, resource planning, and risk screening to improve the management of complex facial traumas within the US trauma system.
Snap-back Repellers and Chaos in a Class of Discrete-time Memristor Circuits
Authors: Marco Mauro Di , FORTI MAURO , Pancioni Luca , Tesi Alberto 
Published: March 2024

Abstract

In the last decade the flux-charge analysis method (FCAM) has been successfully used to show that continuous-time (CT) memristor circuits possess for structural reasons first integrals (invariants of motion) and their state space can be foliated in invariant manifolds. Consequently, they display an initial condition dependent dynamics, extreme multistability (coexistence of infinitely many attractors) and bifurcations without parameters. Recently, a new discretization scheme has been introduced for CT memristor circuits, guaranteeing that the first integrals are preserved exactly in the discretization. On this basis, FCAM has been extended to discrete-time (DT) memristor circuits showing that they also are characterized by invariant manifolds and they display extreme multistability and bifurcations without parameters.This manuscript considers the maps obtained via DT-FCAM for a circuit with a flux-controlled memristor and a capacitor and it provides a thorough and rigorous investigation of the presence of chaotic dynamics. In particular, parameter ranges are obtained where the maps have snap-back repellers at some fixed points and as such they display chaos in the Marotto and also in the Li-Yorke sense. Bifurcation diagrams are provided where it is possible to analytically identify relevant points in correspondence with the appearance of snap-back repellers and the onset of chaos.The dependence of the bifurcation diagrams and snap-back repellers upon the circuit initial conditions and the related manifold is also studied.
Anti- dipeptidyl-peptidase-like protein 6 Epstein-Barr virus encephalitis with prior meningitis: a case report and 2 years follow-up
Authors: Wu Guolu , Shi Yanhui , Sun Jialan , Wu Feifei , Jiang Mei , Li Qiang 
Published: March 2024

Abstract

Background
Anti-dipeptidyl-peptidase-like-protein 6 (DPPX) encephalitis is a rare type of autoimmune encephalitis typically characterized with weight loss, Central nervous system (CNS) hyperexcitability symptoms, and cognitive symptoms. However, increasing case reports suggest a more diverse clinical presentation. We report a case of insidious onset anti-DPPX encephalitis with previous history of Epstein-Barr virus (EBV) meningitis, diagnosed with gastric cancer after 2 years follow-up.
Case presentation:
a 72-year-old emaciated male presented with recurrent seizures during the last 20 years, personality changes over 10 years and memory loss in recent 2 years, with a clear history of viral meningitis in his childhood. Laboratory tests showed CSF positive IgG antibody to EBV virus, and serum positive DPPX antibody, MRI showed no significant changes, which supported the diagnosis of anti-DPPX encephalitis and previous EBV meningitis combined with his medical history. Two years after discharge, he was diagnosed with gastric cancer with multiple metastases receiving palliative care. In this report, we reviewed the clinical manifestations and characteristics of anti-DPPX encephalitis and explored the correlation among EBV infection, anti-DPPX encephalitis and gastric cancer.
Conclusions
The case illustrates a rare circumstance of EBV meningitis in the childhood, a long-stand stable course of anti-DPPX encephalitis and subsequent gastric cancer. Through this case report, we want to raise the awareness among clinical neurologists of anti-DPPX encephalitis even in patients with chronic course and strengthen the screening for malignancy in these patients.
Study on the regulation of resin carbon distribution based on water-alcohol system and its effect on the toughness of carbon paper
Authors: Zhao Shuangshuang , Meng Ling , Li Hailong , Liu Mengru , Song Chengying , Chen Dong , Hu Jian 
Published: March 2024

Abstract
Carbon paper is widely used in the gas diffusion layer of proton exchange membrane fuel cell because of its good mechanical strength, electrical conductivity and dimensional stability. However, brittleness has become a major challenge in its application. In this study, binary mixed solution was used as the diluent of alcohol-soluble phenolic resin to improve the fracture toughness and air permeability of carbon paper. It is found that alcohol-soluble phenolic resin can stably exist in aqueous alcohol solution with anhydrous ethanol volume fraction of not less than 60%. In the impregnation system with different volume fractions of anhydrous ethanol, the distribution form of resin carbon can be effectively regulated, so that the resin carbon is mainly distributed in the lap position of carbon fiber in the form of blocks rather than flakes, which not only ensures the good adhesion of chopped carbon fiber, but also improves the toughness and air permeability of carbon paper.. The results show that the carbon paper prepared in the impregnation system with 60% anhydrous ethanol has higher tensile strength (9.9 MPa), higher fracture toughness (7.6 MJ/m3) and better air permeability (1.39×105 mL·mm/ ( cm2·h·mmHg)). This work provides a reference for the regulation of resin—carbon distribution and the toughness enhancement of carbon paper.
Metamaterials for a Passive Wave Control and Energy Absorption Using Soft-Walled Billiard Effects
Authors: Pilipchuk Valery 
Published: March 2024

Abstract

Physical principles for designing cellwise mechanical met-amaterials with energy-absorbing/harvesting and wave guiding properties are discussed in the present work. The evolution of both propagating and standing waves in a one-dimensional lattice of 3D massive potential wells with light particles inside is analyzed. The potential wells/containers represent soft-wall versions of chaotic billiards that coupled with elastic springs as a one-dimensional chain. The proposed shape function allows for a switch from the repelling to the stadium type of container walls by varying the shape control parameter. The results reveal how the geometry of containers affects the intensity and ir-reversibility of energy flows from the chain of containers into the ensemble of light inclusions. Typically, cells with repelling boundaries generate a chaotization of inclusions and hence the energy absorption in a faster temporal rate. As a result, propagating waves are trapped by giving rise to standing waves of chaotic mode shapes with decaying amplitudes.
Effects of human activities on the genetic characteristics of Phaius flavus populations
Authors: Liang Cuiyi , Li Jun , Li Shixing , Zhang Huayuan , Zheng Jiahao , Miao Jianglin , Hao Siyuan , Wu Shasha , Liu Zhongjian , Zhai Junwen 
Published: March 2024

Abstract
Human activity often has profound effects on plant growth and evolution. Orchids are the most diverse group of flowering plants and are threatened by habitat fragmentation, over-harvesting, and urbanization. A population of Phaius flavus from Beikengding Mount (BM) in Fujian Province was divided into two patches by road construction, and its genetic characteristics were evaluated using restriction site-associated DNA sequencing (RAD-seq) data. The purpose of this study is to explore the impact of road construction on the evolution of different patches within a population. Analysis revealed that the genetic diversity of patch B was slightly higher than that of patch A in the BM population of P. flavus. Principal component and phylogenetic analyses, genetic structure, genetic differentiation, and bottleneck detection indicated phase-independent genetic differentiation between the two patches. Thus, the construction of the Y013 village road may have influenced different patches of this population on a genetic level. This study provides a rational basis for research on the impact of human activities on biodiversity conservation.
Predictive value of coagulation profiles for Kawasaki Disease Shock Syndrome: a prospective cohort study
Authors: Li Bowen , Liu Xiaoliang , Shao Shuran , Wu Ping , Wu Mei , Liu Lei , Hua Yimin , Duan Hongyu , Zhou Kaiyu , Wang Chuan 
Published: March 2024

Abstract
Background
Kawasaki disease (KD) is an acute febrile inflammatory disorder that can progress to a more severe condition known as Kawasaki disease shock syndrome (KDSS). The aim of this study is to comprehend the clinical characteristics of KDSS and investigate the predictive value of the coagulation profiles in the occurrence of KDSS.
Method
Patients with KD were prospectively enrolled and divided into the KDSS group (n = 29) and non-KDSS group (n = 494). Multivariate logistic regression analysis was employed to ascertain the relationship between coagulation profiles and KDSS. Furthermore, ROC curve analysis was conducted to assess the predictive value of the coagulation profile in the occurrence of KDSS.
Result
Among the KDSS patients, the median age was higher and the proportion of cervical lymph node involvement was greater compared to the non-KDSS group. Adverse events including pericardial effusion, valve regurgitation, cardiac enlargement, coronary artery lesions (CALs), and Intravenous immunoglobulin (IVIG) resistance were also significantly higher in the KDSS group than in non-KDSS group. Notably, Prothrombin time (PT), activated partial thromboplastin time (APTT), D-dimer, and fibrin degradation products (FDP) were significantly elevated in the KDSS group compared to the non-KDSS group. Conversely, total thrombin time (TT), fibrinogen, and antithrombin III (ATIII) activity were significantly reduced. Multivariate logistic regression analysis revealed that PT, APTT, D-dimer, and ATIII were independent risk factors for predicting KDSS occurrence. ROC curve analysis established critical values for PT, D-dimer, FDP, and ATIII as 13.45 s, 2.03 mg/L, 7.45 µg/mL, and 77.5%, respectively. Sensitivity for predicting KDSS occurrence was 76%, 79%, 83%, and 76%, while specificity was 51%, 72%, 63%, and 80%, respectively.
Conclusion
Characteristic features of KDSS include older age, a greater likelihood of experiencing pericardial effusion, valve regurgitation, cardiac enlargement, CALs, and IVIG resistance. KD patients with a hypercoagulable state during the acute phase are at a higher risk of developing KDSS.
Green polyurethane foams: Replacing petrochemical polyol with castor oil through factorial design
Authors: Alves Lucas Repecka , Carriello Giovanni M. , Pegoraro Guilherme M. , Moraes Carlos E. , Rezende Maira de L. , de Menezes Aparecido J. 
Published: March 2024

Abstract

Polyurethanes are renowned for their incredible versatility. They are available in various forms, such as foams, thermoplastics, elastomers, and paints. These polymers are synthesized from two chemical substances: isocyanates and polyols. The increasing interest in the utilization of materials from renewable sources has spurred significant research in search of replacements for these two substances. For instance, castor oil can be used as a substitute for polyol, in addition to being an abundant renewable source. In this context, the objective of this study is to investigate how the variables temperature (2°C, 24°C, and 70°C) and mass ratio (2:1, 1:1, and 1:2) influence the final properties of polyurethane foams. The foams were prepared using the one-shot method under controlled agitation. The results indicated that replacing polyol with vegetable oil was successful, as evidenced by the appearance of reference bands in the FTIR spectra. XRD and DSC analyses confirmed the amorphous nature of the polyurethanes, and TG tests demonstrated that a temperature of 70°C significantly reduced the thermal stability of the foams, especially those based on vegetable sources. However, synthesis temperatures of 2°C and 24°C did not show considerable alteration in thermal stability.
A resilient Digital Watermarking Approach for Digital Images using Probabilistic Neural System
Authors: Battarusetty Lakshmana Rao , B Showri Rayalu , V Chiranjeevi S 
Published: March 2024

Abstract
The Digital data and information can be distributed more easily due to the rapid expansion in the use of individual computers, the internet, and digital multimedia technologies. The accessibility of a widespread assortment of image processing tools, however, makes it easier for such data to be used improperly. Digital data can be easily copied, deleted, or modified by unauthorized users or attackers. The prevalence of unauthorized alteration and replication of digital data prompts the development of new methods for safeguarding the IPR of digital information. Watermarking has emerged as a key technique for achieving authentication and copyright protection. All the spatial and frequency domains of host data may incorporate a digital watermark. The present article presents a hybridized technique that syndicates discrete wavelet transformation and singular value decomposition.
Comparative transcriptome profile of embryos at different developmental stages derived from somatic cell nuclear transfer (SCNT) and In-vitro fertilization (IVF) in riverine buffalo (Bubalus bubalis)
Authors: Kumar Deepak , Tiwari Manish , Goel Pallavi , Singh Manoj Kumar , Selokar Naresh Lala , Palta Prabhat 
Published: March 2024

Abstract

Somatic cell nuclear transfer (SCNT) is a very important reproductive technology with many diverse applications, such as fast multiplication of elite animals, the production of transgenic animals and embryonic stem (ES) cells. However, low cloning efficiency, a low live birth rate and the abnormally high incidence of abnormalities in the offspring born are attributed to incomplete or aberrant nuclear reprogramming. In SCNT embryos, the aberrant expression pattern of the genes throughout embryonic development is responsible for the incomplete nuclear reprogramming. The present study was carried out to identify the differential gene expression (DEGs) profile of the SCNT and IVF embryos at different developmental stages (2 cells, 4 cells and blastocyst stages). In the present study, 1164 (2 cells), 1004 (8 cells) and 530 (blastocyst stage) DEGs were identified in the SCNT embryos as compared to IVF embryos. In addition, several genes such as ZEB1, GDF1, HSF5, PDE3B, VIM, TNNC, HSD3B1, TAGLN, ITGA4 and AGMAT were affecting the development of SCNT embryos as compared to IVF embryos. Different molecular functions, biological process, cellular component and molecular pathway affected the development of embryos throughout the different developmental stages in SCNT. Apart from this, q-PCR analysis of the GDF1, TMEM114, and IGSF22 genes were utilized to validate the RNA-seq data. These data sets offer the vital information regarding embryo development in SCNT embryos as compared to IVF embryos.