bluuebunny/crossref_metadata_2025_split huggingface dataset:
Recurrent zinc‐responsive dermatosis in a Siberian Husky
Authors: DEGRYSE A.‐D. , FRANSEN J. , CUTSEM J. VAN , OOMS L. 
Published: April 2008

ABSTRACTZinc‐responsive dermatosis was diagnosed in a Siberian Husky. Oral therapy with zinc sulphate (50 mg essential zinc) resulted in complete clinical recovery, proven by histological examination after one month. Discontinuation of a one‐year‐lasting treatment resulted in relapse with identical skin lesions within two months, but resumption of the therapy once more resulted in complete healing.
Fanconi's syndrome in a Yorkshire Terrier
Authors: McEWAN N. A. , MACARTNEY L. 
Published: April 2008

ABSTRACTA five‐year‐old Yorkshire Terrier with a history of polyuria, polydipsia and glycosuria was referred for investigation and treatment of suspected diabetes mellitus. Despite persistent glycosuria, blood glucose levels remained within the normal range. The dog's condition deteriorated rapidly and euthanasia was carried out. A diagnosis of the Fanconi syndrome was made.
Some observations on the dilution, cooling and freezing of canine semen
Authors: YUBI A. CALDERON , FERGUSON J. M. , RENTON J. P. , HARKER S. , HARVEY M. J. A. , BAGYENJI B. , DOUGLAS T. A. 
Published: April 2008

ABSTRACTCanine semen was obtained by digital manipulation from two donor dogs and twelve stud dogs. The sperm‐rich fraction was diluted with either of two different diluents and the survival of spermatozoa before and after freezing was determined. It appeared that there was no difference in the post‐thaw survival rate in either of the diluents used.
An outbreak of suppurative osteoarthritis of the tibiotarsal joint in rabbits caused by; Pasteurella multocida
Authors: HAGO B. E. D. , A/MAGID O. Y. , SSNOUSI S. M. EL , GAMEEL A. A. , ABU‐SAMRA M. T. 
Published: April 2008

ABSTRACTAn outbreak of suppurative osteoarthritis of the tibiotarsal joint in 25 rabbits in a colony of 50 animals is described. Pasteurella multocida was isolated in pure culture from the affected joints.
Ehlers‐Danlos syndrome in a dog: ocular, cutaneous and articular abnormalities
Authors: BARNETT K. C. , COTTRELL BEVERLEY D. 
Published: April 2008

ABSTRACTEhlers‐Danlos syndrome (EDS) is an hereditary connective tissue disease in man in which the skin is easily torn. A similar condition has been described in dogs and other animals. This case report records a case in the United Kingdom in which the whole syndrome was exhibited: skin fragility, joint laxity and ocular signs of bilateral lens luxation, cataract and corneal oedema. It is the first report of ocular signs in EDS in the dog and joint laxity has been reported only rarely.
Matching dogs to owners—10 years of ‘Selectadog’
Authors: EDNEY A. T. B. 
Published: April 2008

ABSTRACTThe purpose of this paper is to explain what the ‘Selectadog’ programme is, to emphasize some things it is not, to show what it is for and who benefits, to detail the forms that it is in, to give some indication as to how it works and to relate some of the experiences of using ‘Selectadog’ in the United Kingdom and elsewhere since 1975.‘Selectadog’ is a programme designed to match up the characteristics of the more popular breeds of dog to the circumstances of potential owners, as identified by means of a questionnaire. Its purpose is to give guidance to people thinking about getting a dog and above all to make them think through the points they should be considering about fitting a new dog into their lives. At best and it is quite a good best, it can give the prospective owner a number of leads and a positive starting point. It also provides a good deal of free advice and information to allow the new owner to begin a prolonged period of responsible pet animal ownership, without putting them off unnecessarily.
Training dogs based on behavioural methods
Authors: OWREN T. 
Published: April 2008

ABSTRACTThe nature of the dog's behaviour is reviewed. The nervous system is activated by afferent nerve impulses generated in various sense‐organs. The sum of internal (motivation) and external stimuli is analysed in a steady state system. A marked discrepancy between important set values and their actual values will make the organism react.A communication system consisting of the dog handler, the dog, signals and key‐stimuli and other external influences (noise), is used when training a dog. The change of behaviour is more permanent and a new behaviour pattern is established more rapidly when the training is organized in such a way that key‐stimuli and conditioned signals which elicit wanted behaviour sequences are reiterated many times before a verbal command is added to the stimuli. A dog handler must also know the activation of emotional behaviour. Stress, coping and aggression are expressions used to describe such activation.A general check‐list to be used when starting training tasks are suggested. The exercise ‘retrieve’ is used as an example.
Angiographic examination of the forelimb in dogs with abnormal growth of the distal radius and ulna
Authors: KOMA L. M. P. K. , STEAD A. C. 
Published: April 2008

ABSTRACTBrachial angiograms were performed on 13 forelimbs from 12 dogs with growth‐plate disorders of the distal radius and ulna. Eight angiograms were considered normal and five showed failure of individual arteries to fill, in two cases associated with hypertrophy of other vessels. Angiography was too insensitive to identify the small vessels which supplied the growth plates.
Chronic granulocytic leukaemia in a dog with associated bacterial endocarditis, thrombocytopenia and preretinal and retinal haemorrhages
Authors: DUNN J. K. , JEFFERIES A. R. , EVANS R. J. , HERRTAGE M. E. 
Published: April 2008

ABSTRACTThe clinical, haematological and pathological features of a case of chronic granulocytic leukaemia (CGL) associated with valvular bacterial endocarditis are described in a nine‐year‐old male Springer Spaniel. The disease was characterized clinically by lethargy, weight loss, hepatosplenomegaly, anaemia and leucocytosis. Severe thrombocytopenia resulted in preretinal and retinal haemorrhages. A diagnosis of CGL was based on the finding of a hypercellular bone marrow with increased M: E ratio and morphologically abnormal myeloid precursors. The dog terminally became leucopenic and bacteraemic. Necropsy revealed invasion of liver, spleen and bone marrow with a pleiomorphic population of myeloid blast cells, consistent with transition to a blast cell crisis.
Primary lung tumours in the cat
Authors: BARR F. , GRUFFYDD‐JONES T. J. , BROWN P. J. , GIBBS C. 
Published: April 2008

ABSTRACTSeventeen cats with primary lung tumours were referred to the University of Bristol Veterinary School between 1970 and 1986. Clinical, radiographic and pathological findings were recorded in each case. Analysis of these findings allowed assessment of those features most helpful in reaching a definitive diagnosis.
Latent feline leukaemia virus infection: a review
Authors: PACITTI ANGELA M. 
Published: April 2008

ABSTRACTMany cats which apparently recover from natural exposure to feline leukaemia virus (FeLV) are latently infected with the virus. While no infectious virus is isolated from blood, latent virus is found in bone marrow. This review describes the prevalence and duration of such infections, possible mechanisms involved in their maintenance, and their clinical and epidemiological significance.
Immune‐based erosive inflammatory joint disease of the dog: canine rheumatoid arthritis.
Authors: BENNETT DAVID 
Published: April 2008

ABSTRACTThe pathological features of 30 cases of canine rheumatoid arthritis are described. The principle pathological feature is a chronic symmetrical polysynovitis. The pathological features of the joints varied in severity. The synovial membrane generally showed villous hypertrophy with aggregates of lymphocytes and plasma cells. Destruction of articular cartilage and bone occurred in association with a replacement granulation tissue which often produced a pannus over the articular surface. Immunofluorescence studies demonstrated complexes of IgG or IgM with C3 in synovial lining cells, macrophages, blood vessel walls and free in the extracellular tissues. IgG and IgM producing plasma cells were also common. Fibrinogen deposits were extensive. The immunofluorescence findings were non‐specific but support the concept of an immune complex mediated inflammation within the joints. Investigations for bacterial, mycoplasmal and viral infections of the joints were negative.
Feline neonatal isoerythrolysis in two litters
Authors: HUBLER M. , KAELIN S. , HAGEN A. , FAIRBURN A. , CANFIELD P. , RUESCH P. 
Published: April 2008

ABSTRACTThe clinical, pathological and serological findings for feline neonatal isoerythrolysis (FNI) in two litters are described. In each litter one of four kittens died shortly after birth, two showed varying degrees of depression, jaundice and haemoglobinuria and one remained healthy (clinically unaffected). Three of the kittens with jaundice died and the necropsy findings included variable degrees of erythrophagocytosis in the spleen and liver and many casts containing haemoglobin in the tubules and collecting ducts of the kidney. Blood typing and haemocompatibility testing were performed on the surviving kittens, queens and sires. Both queens and the healthy kittens were Type B while both sires and the surviving affected kitten were Type A. In both litters the queens sera haemolysed the sires erythrocytes but did not affect the erythrocytes of the healthy kittens. The erythrocytes of the surviving affected kitten were haemolysed by the serum of its queen. The pathogenesis and treatment of FNI are discussed.
BSAVA EDUCATION COMMITTEE COMMISSIONED ARTICLE: Anaerobic bacteria: a cause of infection?
Authors: MACKINTOSH MARY E. 
Published: April 2008

ABSTRACTThis review article considers the evidence available for a significant role of obligate anaerobes in infections of small animals.The presence of anaerobes in the normal flora and the meaning of the terms aerobe and anaerobe both in relation to the bacterial metabolism and laboratory culture is discussed.The reported findings of anaerobes in clinical veterinary conditions are reviewed. The particular importance of the non‐sporing (non‐clostridial) anaerobes in traumatic and endogenous infections and the mixed nature, both in terms of different anaerobes and mixed aerobes and anaerobes of such infection are considered.Some experimental evidence for the pathogenicity of obligate anaerobes and their complex role in mixed infections is given.Observations on the use of antibiotics for treatment of suspected anaerobic infections are discussed and the possible implications to laboratory procedures for antibiotic sensitivity testing.
Pharmacological studies
Authors: BROUWER G. J. 
Published: April 2008

SUMMARYInterpretation of the results requires some caution as a result of the limited number of trials carried out; in particular, the lack of suitable control data has to date, remained a source of concern. Nevertheless some trends are apparent.The results demonstrate that both the sympathetic and parasympathetic nervous systems appear to be affected. Direct stimulation of sympathetic and parasympathetic post‐synaptic receptors gives measureable results suggesting that the integrity, at least in part, of these receptors is maintained. Since the effect of indirect agents was negative in four cats and reduced in a fifth the functioning of both sympathetic and parasympathetic post‐ganglionic fibres appears to be defective. This provides additional evidence, albeit circumstantial, that the dysautonomia arises from dysfunction at the ganglionic level or above.Studies aimed at determining ganglionic function are fraught with difficulty in that both sympathetic and parasympathetic ganglia function in similar ways and therefore, pharmacological trials which will elicit differences in dysfunction between the two autonomic divisions are not easy to devise.This study has shown qualitative differences between actions of several drugs which have served to confirm present knowledge and understanding of Feline Dysautonomia. It may ultimately be possible to design these tests to give quantitative results which may be used, not only to confirm diagnosis but also to aid with prognosis as to the course of the disease. It may also be possible to develop some of these tests so that they may be performed in the conscious animal, particularly with the view to monitoring progress of the disease without the need to use invasive techniques.
Poisoning in four dogs by a compound containing warfarin and calciferol
Authors: MacKenzie C. P. , Burnie A. G. , Head K. W. 
Published: April 2008

ABSTRACTOf four dogs which had ingested rat poison containing calciferol and warfarin, two survived and two died. The case histories including pathological findings of these dogs are presented and the biochemical effects and treatment of calciferol poisoning are discussed.
Hyperthermia and radiation in the management of canine tumours
Authors: THOMPSON J. M. , GORMAN N. T. , BLEEHEN N. M. , OWEN L. N. , WHITE R. A. S. 
Published: April 2008

ABSTRACTFifty‐one dogs bearing a variety of naturally occurring tumours were treated with combined radiation and hyperthermia. The treatment regime consisted of four, weekly fractions of radiation to a total dose of 3600–4000 cGys and one or two treatments with local microwave hyperthermia, heating the tumour to 44°C for 30 minutes on each occasion.Twenty‐six (51 per cent) of the tumours showed a complete response to this treatment and a further eighteen (35 per cent) tumours underwent significant regression giving a total response rate of 86 per cent. Sixteen tumours later recurred at intervals of 11–50 weeks post treatment. The majority of tumours were in the oral cavity (35 cases) and in this group the survival rate compares favourably with figures for surgical treatment and radiotherapy alone.These findings support published results from other centres, indicating that hyperthermia combined with radiotherapy is a potentially useful technique for the management of certain canine malignant tumours.
A case of hyperplastic gastropathy in a cat
Authors: Dennis R. , Herrtage M. E. , Jefferies A. R. , Matic S. E. , White R. A. S. 
Published: April 2008

ABSTRACTPrimary hyperplastic gastropathy is an uncommon human disease characterized by giant gastric mucosal folds and is associated with a spectrum of histopathological changes. Diagnosis is usually made on radiological and gastroscopic findings followed by full‐thickness biopsy of the stomach wall. The aetiology is unknown and symptomatic treatment is usually disappointing. A similar condition has been described in a small number of dogs.A case of hyperplastic gastropathy is reported in a cat and compared with the findings in man and dogs. The cat presented with chronic vomiting and weight loss. Radiological and gastroscopic examinations revealed enlarged gastric rugae. Medical and surgical treatment was unsuccessful and the cat was destroyed. The pathological findings were similar to those described in man.
Thyroid tumours in the dog
Authors: SULLIVAN M. , COX F. , PEAD M.J. , McNELL P. 
Published: April 2008

ABSTRACTThe clinical, radiological and histopathological features of 30 thyroid tumours in the dog are described. Ten tumours were considered suitable for surgical removal and in a follow‐up period of between 14 and 36 months five dogs were still alive.
The responsible use of chloramphenicol in small animal practice. 1. Pharmacological considerations
Authors: KNIFTON A. 
Published: April 2008

ABSTRACTThree important criteria which the clinician should consider when selecting an antibiotic are its antibacterial spectrum, pharmacokinetic properties, and potential toxicity. Pharmacokinetics is a study of how the body handles drugs: that is, their absorption, distribution in the tissues (an antibiotic must reach the site of infection in effective concentration), metabolism and excretion.This article reviews these criteria with respect to chloramphenicol in dogs and cats.
Idiopathic renal haemorrhage in the dog
Authors: HOLT P. E. , LUCKE V. M. , PEARSON H. 
Published: April 2008

ABSTRACTThe clinical, radiographic and pathological features of idiopathic renal haemorrhage are described in nine dogs. Diagnosis necessitated catheterization of each ureter. Unilateral bleeding was found in seven dogs and bilateral bleeding in two. The response to nephrectomy was good in those animals affected unilaterally. Lesions which accounted for the bleeding were detected microscopically in only two dogs.
Canine fucosidosis: clinical findings
Authors: TAYLOR R. M. , FARROW B. R. H. , HEALY P. J. 
Published: April 2008

ABSTRACTThe clinical course of canine fucosidosis, a neurovisceral lysosomal storage disease, is described from observations of 31 affected English Springer Spaniels. The diagnosis of fucosidosis was suggested by the development of multifocal neurological signs in the second year of life and confirmed by a deficiency of alpha‐L‐fucosidase activity in plasma and leucocytes. The progressive motor and mental deterioration was similar in all dogs and no affected animal survived to four years of age. Alpha‐L‐fucosidase activity in plasma was <0·05 μ/1 in all cases. The activity in leucocytes and other tissues was < 5 per cent of that of normal dogs.Vacuolated leucocytes occurred in cerebrospinal fluid, blood and bone marrow. The enlargement of peripheral nerves which is observed at autopsy could be detected by palpation of the ulnar nerve in advanced disease, however the results of electrodiagnostic studies were within normal limits.The clinical signs and pathological changes were found to be remarkably consistent from case to case making it an excellent model for investigating therapeutic strategies in human lysosomal storage disorders.
Acquired arteriovenous fistula in a dog following perivascular injection of thiopentone sodium
Authors: TURNER B. M. 
Published: April 2008

ABSTRACTAn acquired arteriovenous fistula between the distal collateral radial and median arteries arising from the brachial artery, and the cephalic, brachial and median cubital veins of the right foreleg in an 8‐year‐old Afghan Hound is described.The arteriovenous fistula was apparently acquired two years previously after a perivascular injection of the anaesthetic agent thiopentone sodium in 5 per cent W/V solution* and was found as an incidental problem during an examination for an unrelated lameness problem. The arteriovenous fistula was characterized by a large pulsatile swelling that had a continuous thrill and bruit. A positive Branham sign was present. The lesion was diagnosed by physical and radiological examination.Ligation of the brachial artery has provided some post‐operative improvement in exercise tolerance.
The management of total tongue avulsion in a dog: a case report
Authors: CLUTTON R. E. , RICHARDS D. L. S. 
Published: April 2008

ABSTRACTA 17‐month old Dobermann Pinscher bitch was presented with a self‐induced, total avulsion of the tongue. Clinical signs of haemorrhagic shock were present. An inability to swallow led to rapid and progressive dehydration and weight loss. Management was initially directed at the correction of haemorrhagic shock, and then at the maintenance of fluid and energy balance while the tongue root healed by secondary intention. Aggressive parenteral feeding and hydration via a pharyngostomy tube resulted in stabilization of body weight. The dog has since gained weight and can maintain adequate food and water intake. Solid food is taken into the mouth and swallowed with minimal difficulty, although drinking is accompanied by some spillage.
Post‐prandial changes in canine plasma creatinine
Authors: EVANS G. O. 
Published: April 2008

ABSTRACTPost‐prandial changes of plasma creatinine and urea concentrations were found in healthy Beagle dogs fed a pelleted diet. Changes of plasma creatinine determined using an alkaline picrate method were confirmed by a more specific enzymatic method. The study also showed that alkaline picrate methods over‐estimate plasma creatinine in dog plasma.
Book Reviews
Authors: Jones S. M. Petersen 
Published: April 2008

Book reviewed in this article:Canine and Feline Gastroenterology Edited by Brent D. Jones. Published by W. B. Saunders Company. Available in the UK from Holt‐Saunders Ltd., 1 St Anne's Road, Eastbourne, East Sussex BN21 3UN. Price £60.00. 531 pp.Textbook of Small Animal Surgery Edited by Douglas H. Slatter. Published by W. B. Saunders Company. Available in the UK from Holt‐Saunders Ltd, 1 St Anne's Road, Eastbourne, East Sussex, BN21 3UN. Two volumes. Price £95.00 per volume. 2,718 pp.Manual of Small Animal Surgical Therapeutics Edited by C. W. Betts and Stephen W. Crane. Published by Churchill Livingstone, Available in the UK from Longman Group Limited, Longman House, Burnt Mill, Harlow, Essex CM20 2JE. Price £29.00. 426 pp.Veterinary Aspects of Captive Birds of Prey, 2nd Edn: J. E. Cooper. Published by The Standfast Press, Saul, Gloucestershire. Price £15.00. 287 pp.Veterinary Dentistry Erich Eisennmenger and Karl Zetner with the assistance of Franz Schutz and Ben H. Colmery. Published by Lea & Febiger, 600 Washington Square, Philadelphia, PA 19106‐4198. USA Distributed in the UK by Quest‐Meriden Ltd, 145a Croydon Road, Beckenham, Kent BR3 3RB. Price US$48.50. 165 pp.The Doglopaedia J. M. Evans and Kay White. Published by Henston Ltd, Russell House, 137–139 High Street, Guildford, Surrey. Price £5.95. 251 pp.Jone's Animal Nursing, 4th edn. Edited by D. R. Lane, Published by Pergamon Press Ltd, Headington Hall, Oxford OX3 0BW. Price: hard £43.00, flexi £19.50.Veterinary Trauma and Clinical Care Edited by Ira M. Zaslow. Published by Lea & Febiger, 600 Washington Square, Philadelphia, PA 19106‐4198, USA. 584 pp.
Shock — a practitioner's perspective
Authors: MURPHY FINBARR 
Published: April 2008

ABSTRACTGood urine output, capillary refill time and skin hydration have in the past been used as indications of a good prognosis in cases of shock. This is not necessarily the case. Over reliance on these signs can lead to faulty prognosis. Four case histories are presented of animals in shock with particular reference to the above mentioned parameters.
Is it hereditary?: 2. Types and characteristic patterns of hereditary disease
Authors: THRUSFIELD M. 
Published: April 2008

ABSTRACTThis article outlines the three main categories of genetic disease: chromosomal, Mendelian and multifactorial disorders. The modes of inheritance and characteristic patterns of the last two categories are described. This article is the second in a series of three concerned with the identification of an hereditary component to the cause of disease.
Clinical investigation of the lame dog
Authors: BARR A. R. S. , HOULTON J. E. F. 
Published: April 2008

ABSTRACTLameness is a common clinical problem in the dog and a proportion of cases present problems in diagnosis. A systematic approach to their investigation involves history taking, observation of gait and inspection, palpation and manipulation of the suspect limb or limbs. This should allow the clinician to localise and, in many cases, characterise the problem in terms of the likely underlying disease process. This knowledge will then allow recommendations to be made as to the employment of ancillary diagnostic aids.
Quantification of plasma bile acids in the dog with a direct spectrophotometric method
Authors: AGUILERA‐TEJERO E. , MAYER‐VALOR R. , GOMEZ‐CARDENAS G. 
Published: April 2008

ABSTRACTPlasma bile acid estimation has recently been shown to be an excellent indicator of hepatic function in the dog. At the moment the only reported quantification method useful for routine clinical purposes in dogs is a direct spectrophotometric enzymatic technique. This article describes a modification of this method which improves its sensitivity. The problem of processing samples with high levels of lactate dehydrogenase (and more specifically of LDH5), and its clinical significance is also discussed.