bluuebunny/crossref_metadata_2025_split huggingface dataset:
The effect of sense of security on job performance of medical staff: the mediating effect of psychological capital
Authors: Xu Yixuan , Zhan Ningjing , Zhang Dantong , Xie Zhanghao , Li Gege , Huang Huigen 
Published: April 2024

ObjectiveTo investigate the current situation of sense of security, psychological capital and job performance of medical staff in Guangdong Province, and to explore the mediating role of psychological capital on the relationship between sense of security and job performance of medical staff.MethodsIn this study, 969 health care workers were selected from February 2023 to April 2023 from 37 hospitals in Guangdong Province, China, using purposive sampling method. The Sense of Security Scale for Medical Staff (SSS-MS), psychological capital scale (PCS) in Chinese version and the Chinese version of job performance scale (JPS) were used in this study. We use SPSS 26.0 for statistical analysis and Amos 24.0 for structural equation modeling (SEM). The control variables entering SEM were selected by regression analysis. SEM analysis confirmed psychological capital scale's mediating function in the link between work performance scale and Sense of Security.ResultsThe overall SSS-MS, PCS, and JPS scores were 67.42 ± 16.136, 87.06 ± 15.04, and 77.87 ± 10.50, respectively. The results of Pearson's correlation analysis showed that there was a positive relationship between PCS and JPS (r = 0.722, P &lt; 0.01), SSS-MS and JPS (r = 0.312, P &lt; 0.01), and SSS-MS and PCS (r = 0.424, P &lt; 0.01). PCS demonstrated a fully mediating influence on the link between medical workers' SSS-MS and JPS, according to structural equation modeling.ConclusionThe JPS of medical personnel in Guangdong Province is at a medium level, with much room for improvement. PCS is positively impacted by a sense of security. There is a supportive correlation between PCS, JPS, and SSS-MS. Furthermore, PCS fully mediates the relationship between medical staff members' JPS and their SSS-MS. The Job Diamond-Resource model and Conservation of Resource theory are further validated and supplemented by the findings of this study, which also gives managers a theoretical foundation for enhancing medical staff performance.
In vitro study of radiosensitivity in colorectal cancer cell lines associated with Lynch syndrome
Authors: Sun Mingzhu , Moquet Jayne , Barnard Stephen , Mancey Hannah , Burling David , Baldwin-Cleland Rachel , Monahan Kevin , Latchford Andrew , Lloyd David , Bouffler Simon , Badie Christophe , Anyamene Nicola A. , Ainsbury Elizabeth 
Published: April 2024

IntroductionLynch syndrome patients have an inherited predisposition to cancer due to a deficiency in DNA mismatch repair (MMR) genes which could lead to a higher risk of developing cancer if exposed to ionizing radiation. This pilot study aims to reveal the association between MMR deficiency and radiosensitivity at both a CT relevant low dose (20 mGy) and a therapeutic higher dose (2 Gy).MethodsHuman colorectal cancer cell lines with (dMMR) or without MMR deficiency (pMMR) were analyzed before and after exposure to radiation using cellular and cytogenetic analyses i.e., clonogenic assay to determine cell reproductive death; sister chromatid exchange (SCE) assay to detect the exchange of DNA between sister chromatids; γH2AX assay to analyze DNA damage repair; and apoptosis analysis to compare cell death response. The advantages and limitations of these assays were assessed in vitro, and their applicability and feasibility investigated for their potential to be used for further studies using clinical samples.ResultsResults from the clonogenic assay indicated that the pMMR cell line (HT29) was significantly more radio-resistant than the dMMR cell lines (HCT116, SW48, and LoVo) after 2 Gy X-irradiation. Both cell type and radiation dose had a significant effect on the yield of SCEs/chromosome. When the yield of SCEs/chromosome for the irradiated samples (2 Gy) was normalized against the controls, no significant difference was observed between the cell lines. For the γH2AX assay, 0, 20 mGy and 2 Gy were examined at post-exposure time points of 30 min (min), 4 and 24 h (h). Statistical analysis revealed that HT29 was only significantly more radio-resistant than the MLH1-deficient cells lines, but not the MSH2-deficient cell line. Apoptosis analysis (4 Gy) revealed that HT29 was significantly more radio-resistant than HCT116 albeit with very few apoptotic cells observed.DiscussionOverall, this study showed radio-resistance of the MMR proficient cell line in some assays, but not in the others. All methods used within this study have been validated; however, due to the limitations associated with cancer cell lines, the next step will be to use these assays in clinical samples in an effort to understand the biological and mechanistic effects of radiation in Lynch patients as well as the health implications.
Dentists and dental hygienists’ comprehension of HIV infection associated periodontal implications and management
Authors: Ahmed Muzammil Moin 
Published: April 2024

BackgroundIn an era wherein, persuasive evidence continues to witness the association between systemic and periodontal diseases, the absence of scientific data on dental professionals’ comprehension concerning the HIV infection and periodontal link is lamentably backward. Thus, the key objective of this research is to ascertain the extent of comprehension possessed by dentists and dental hygienists concerning periodontal implications and their management in HIV patients.MethodsIt is a quantitative cross-sectional survey employing a descriptive approach focusing on a specific cohort of dental professionals. The study setting featured an online platform for the distribution of concealed, closed-ended, structured questionnaire. The data was gathered for four sections: six comprehension statements about periodontal manifestations in HIV patients; fifteen comprehension statements about HIV patients’ periodontal management; eight familiarity statements about HIV management; and two educational statements about HIV. The comparisons of comprehension scores were drawn between variables such as specialties, age groups, and genders.ResultsThe survey represented 468 dental professionals representing distinct dental specialties, with a mean age of 24.26 ± 7.53 years. The mean comprehension score for all groups of participants is 10.31 ± 9.34 (33.25%). The highest scores were recorded among those aged 31–40 (20.67 ± 8.31), followed by those aged 40+ (19.38 ± 9.39), 20–30 (9.53 ± 8.96), and under 20 (8.92 ± 8.57), at p &lt; 0.001. The female participants (15.06 ± 12.2) exhibited substantially better scores in contrast to the male participants (8.74 ± 7.57). Periodontists (27.77 ± 3.08) comprehended most, then the oral medicine practitioners (25 ± 0). Dental hygiene students (5.52 ± 3.56) and hygienists (7.67 ± 9.72) comprehended the least. The scores for all four domains assessed were disappointingly low: knowledge about HIV-periodontal manifestations (2.81 ± 2.18), knowledge about management of periodontal diseases in HIV patients (3.73 ± 4.7), familiarity with periodontal care in HIV patients (2.87 ± 3.01), and education received about HIV and periodontal diseases (0.91 ± 0.66).ConclusionDental professionals are notably incomprehensive, unfamiliar, and lacking in expertise in the realm of periodontal facets of HIV. The periodontists and oral medicine practitioners showed a substantial amount of comprehension, while the dental hygiene students and dental hygienists presented a conspicuously inadequate level of comprehension. The study outcome could potentially serve as an invaluable instrument for self-assessment by dental professionals and educators. HIV/AIDS ought not to persist as an unspoken taboo or disregarded subject within the dental field, particularly in periodontics, but rather should receive prominence in dental schools and professional development programs.
Experiencing accessibility of historical heritage places with individuals living with visible and invisible disabilities
Authors: Ruiz-Rodrigo Alicia , Morales Ernesto , Lakoud Maryem , Riendeau Jonathan , Lemay Miranda , Savaria Ariane , Mathieu Samuel , Feillou Isabelle , Routhier François 
Published: April 2024

IntroductionAround 16% of world's population lives with visible and invisible disabilities. People with disabilities' participation may be limited because of the environmental obstacles. Moreover, historic heritage places were built before the development of accessibility standards and the rights of people living with disabilities and the majority were not designed to be accessible. Access to historic heritage places is important for carrying out the activities in place but also to create and reinforce identity. The aim of this study was to explore the experiences of people with visible and invisible disabilities when visiting heritage sites considering accessibility issues.MethodsThis study is a qualitative interpretive description. Participants were adults with visible (e.g., motor disability) or invisible (e.g., autism) disabilities. For data collection, go along interviews (also referred to in the literature as “walking interview” in two different locations in the Historic District of Old Quebec in Quebec City were conducted. Thematic analysis was done.ResultsTwenty-one participants completed two go along interviews: one in theSéminaire de Québec(Seminary of Quebec City) and the other in Petit-Champlain and Place Royale areas of Quebec City. Three themes emerged: (1) Obstacles and impact on participation; (2) Disabling accessibility; and (3) Heritage meaning.DiscussionThe barriers identified by participants are diverse and differ according to the person and the type of disability. However, social and leisure activities were particularly limited, despite the strategies developed by some participants. Participants in the study demonstrated an interest in accessing to heritage places, therefore it seems essential to consider the needs of people with disabilities when developing accessibility solutions, and to seek a balance between preserving heritage and promoting inclusive and equitable access for all.
Dynamic Modeling and Simulation of a Facade-Integrated Adsorption System for Solar Cooling of Lightweight Buildings
Authors: Boeckmann Olaf , Marmullaku Drin , Schaefer Micha 
Published: April 2024

Reductions of carbon dioxide emissions from the building sector are mandatory for climate protection. This calls for both a reduction of the construction material and energy as well as a reduction of the operational energy. Against this background, a novel facade-integrated adsorption system for solar cooling of lightweight buildings is proposed and theoretically investigated in this work. For this purpose, a detailed simulation model is developed to analyze both the processes in the single components as well as the overall system behavior. The proposed system consists of the three components adsorber, condenser and evaporator, which are connected vacuum-tight and are coupled by vapor transfer. The simulation results of a defined reference case yield cooling rates of 54 W per installed square meter of adsorber facade. The cooling power can be maintained for 12 h, confirming the applicability of the proposed system. Furthermore, a comprehensive parametric study is carried out in order to identify an optimum set of parameter values for maximum cooling rate under the assumed conditions. The results reveal that controlled constant cooling rates of 105 W per square meter of adsorber facade can be reached and a maximum peak power of 145 W per square meter of adsorber facade is possible.
Il y a dans des corpus oraux d’enfants
Authors: Cappeau Paul , Savelli Marie 
Published: April 2024

Une suite comme « il y a » est un bon exemple pour montrer comment une structure, très présente dans le discours, est pointée négativement, hors norme, non esthétique et mise hors du champ de l’analyse grammaticale. Dans une perspective descriptive, la constitution et l’exploitation morphosyntaxique du corpus oral, qui portent sur cette forme, notamment dans le langage enfantin, permettent :
– d’attester ces usages en français contemporain,
– des comparaisons au-delà des productions exclusivement écrites,
– de combattre certaines idées reçues sur la langue,
– de développer, au-delà du seul critère rhétorique de mise en relief, ou de présentatif, sa distribution et son rôle prédicatif.
Pelatihan “Dasar Komputer Grafis Vektor dalam Ilustrasi Digital” untuk Seniman Jalanan di Komunitas Lingkar Rupa, Kota Tua, Jakarta
Authors: Rahardjo Fransisca Retno 
Published: April 2024

Seniman jalanan di Kota Tua adalah seniman otodidak yang berasal dari golongan ekonomi menengah ke bawah sehingga tidak punya biaya untuk sekolah dan belajar keterampilan seni secara formal apalagi mengembangkan keterampilan digital ke intitusi desain. Padahal keterampilan desain garfis saat ini sangat penting untuk merespon kebutuhan visual di masyarakat modern. Kemampuan digital memiliki keuntungan yang dapat memangkas waktu bagi kebutuhan mendesak ditengah mobilitas produksi konsumsi industry kreatif yang cukup padat. Selain itu teknik dan media computer juga dapat meningkatkan nilai jual suatu karya seni yang berskala souvenir. Oleh karena itu penulis berniat untuk membuat suatu lokakarya mengenai ilmu dasar komputer grafis yang relevan dengan pekerjaan target sasaran para seniman jalanan yaitu produsen ilustrasi. Pengajaran pembuatan ilustrasi digital diharapkan mampu mengakselerasi ketrampilan para seniman otodidak tersebut dalam waktu yang cukup singkat yaitu dalam waktu dua hari saja. Penulis akan memberikan pelatihan pembuatan vector, pemberian tugas, dan evalusasi serta menyediakan bahan software atau aplikasi yang akan digunakan. Dengan demikian para seniman jalanan inipun dapat meningkatkan taraf kehidupan mereka ke arah yang lebih baik juga dapat masuk dalam perhitungan para pelaku industry kreatif di dunia seni dan desain yang begitu luas.
Kajian Kapasitas Pelimpah dan Terowongan Konduit Bendungan Sawangan dalam Mereduksi Debit Puncak Banjir
Authors: Wibowo Agus Aris , Sangkawati Sri , Nugroho Hari 
Published: April 2024

Penelitian ini bertujuan untuk menetapkan banjir desain dan kapasitas bangunan pelimpah serta untuk mengetahui efektivitas bangunan keluaran waduk (pelimpah dan Konduit) terhadap reduksi banjir secara maksimal. Lokasi wilayah penelitian adalah rencana pembangunan Bendungan Sawangan Kota Manado. Data penelitian ini berdasarkan data hidro-klimatologi, , data teknis bendungan dan waduk. Selain itu terdapat data penunjang untuk melakukan perhitungan dan analisis, seperti data debit banjir, kurva elevasi – volume waduk dan tata letak bendungan serta bangunan pelengkapnya. Metode yang digunakan adalah melakukan perhitungan penelusuran banjir (flood routing) terhadap keluaran waduk (outlet) melalui pelimpah dan terowongan konduit (bottom outlet).Penelusuran banjir dilakukan dengan menggunakan hidrograf inflow banjir rancangan PMF Probable Maximum Flood (PMF) sehingga reduksi banjir maksimal dapat ditentukan pada rencana pola operasinya bila konduit dilengkapi dengan pintu. Optimalisasi reduksi debit puncak banjir dilakukan dengan skenario pelimpah tanpa konduit dan skenario pelimpah dengan konduit. Paramater yang dipergunakan adalah dengan menggunakan parameter lebar pelimpah, tinggi / elevasi pelimpah dan dimensi konduit, sedangkan ukuran / kontrol scenario optimalisasi adalah tinggi sisa jagaan banjir di pelimpah, rasio kapasitas pelimpah dan reduksi debit puncak banjir inflow-outflow Bendungan Sawangan. Hasilnya kajian dan analisis adalah perbandingan optimalisasi skenario 1 pelimpah tanpa konduit dan skenario 3 pelimpah dengan konduit diperoleh hasil reduksi debit puncak banjir PMF cukup signifikan yaitu scenario 1 reduksinya sebesar 19,0 % dan skenario 2 sebesar 36,6 %. Konfigurasi yang diperoleh adalah elevasi puncak pelimpah pada elevasi +35,0 m, lebar pelimpah 20,0 m, dan 2 buah konduit diameter 5,0 m terbuka penuh (open fully). Reduksi debit puncak banjir PMF dihasilkan dari inflow sebesar 1260,8 m3/det menjadi outflow sebesar 798,98 m3/det atau sebesar 36,6 % dengan tinggi jagaan sisa 1,79 m dan rasio kapasitas pelimpah 63,4 %.
Faktor-faktor yang Mempengaruhi Produktivitas Tenaga Kerja Konstruksi: Tinjauan Literatur
Authors: Nurhendi Revianty Nurmeyliandari , Bastam Mukhlis Nahriri 
Published: April 2024

Produktivitas konstruksi mempunyai hubungan yang erat dengan produktivitas tenaga kerja konstruksi. Produktivitas tenaga kerja dalam konstruksi memiliki peran yang sangat penting dalam mencapai keberhasilan proyek. Hal ini melibatkan banyak aspek, mulai dari memastikan progres yang cepat, pengendalian biaya yang efisien, hingga menghasilkan kerja yang berkualitas tinggi. Oleh karena itu, manajemen dan pengelolaan produktivitas tenaga kerja konstruksi yang efisien dan efektif menjadi factor krusial dalam mencapai sebuah proyek konstruksi yang sukses. Dengan produktivitas tenaga kerja konstruksi yang tinggi, proyek konstruksi dapat di selesaikan lebih cepat, lebih efisien dan lebih menguntungkan. Sehingga produktivitas yang baik harus dikelola dengan baik oleh tim manajemen proyek untuk mencapai keberhasilan proyek konstruksi. Salah satu upaya untuk meningkatkan produktivitas tenaga kerja koknstruksi adalah dengan memahami dan mengidentifikasi faktor-faktor yang dapat mempengaruhi produktivitas tenaga kerja konstruksi. Dengan mengidentifikasi faktor-faktor yang dapat memberikan pengaruh positif dan negative terhadap produktivitas tenaga kerja konstruksi tersebut maka dapat membantu tim manajemen proyek untuk meningkatkan produktivitas tenaga kerja konstruksi, yang akhirnya keberhasilan sebuah proyek konstruksi dapat dicapai dengan lebih mudah
The construction productivity has a close relationship with construction labour productivity. The labour productivity in construction has a crucial role to play in achieving project success. This involves many aspects, from ensuring fast progress, efficient cost control, to providing high quality work. Therefore, efficient and effective management and management of construction labour productivity is a crucial factor in achieving a successful construction project. With high construction labour productivity, construction projects can be completed faster, more efficiently and more profitably. Hence, high productivity must be well managed by the project management team to achieve a successful construction project. One of the efforts to improve construction labour productivity is to understand and identify factors that can affect construction labour productivity. The identification of factors that can positively and negatively affect the productivity of construction labour can help the project management team to improve the productivity of construction labour, which in turn can make the success of a construction project easier to be accomplished.
HIPOTIROIDISMO EN GERIATRÍA Y SUS DECISIONES TERAPÉUTICAS: REVISIÓN DE LITERATURA ACTUAL.
Authors: Vera Javier Enrique Dominguez , Lorenti Denisse Johanna Romero , López Dunia Alejandra Quintero , Ron Santiago Andres Ruiz , Solis Marilyn Liliana Ramirez , Zambrano Andrea Lissette Chong , Romina Vera Alvarado Kristell , Ramos Sandra Katherine Bajaña , Herrera Katherine Lissette Rodríguez , González Wicle Arturo Vera , Ávila Luis Eduardo López , Jiménez Paola Anabel Hurtado 
Published: April 2024

El hipotiroidismo (HT), una condición endocrina crónica que implica una producción insuficiente de hormonas tiroideas, tiene una prevalencia notable en la población geriátrica (PG). A medida que la PG crece, también lo hace la incidencia de HT, lo cual afecta la calidad de vida de estos pacientes. Objetivo: Esta revisión analiza la literatura científica actual sobre el HT en geriatría, con el objetivo de optimizar su manejo clínico. Metodología: Se realizó una revisión bibliográfica en diversas bases de datos médicas, seleccionando estudios que abordaran el HT en PG y sus opciones de tratamiento. Resultados: El manejo de HT primario grave (HTPG) implica considerar la edad y el grado de hipotiroidismo. Se sugiere que un nivel de TSH superior a 10 mU/l podría ser un umbral razonable para considerar el tratamiento, aunque este umbral debe ser revisado periódicamente. El HTPG presenta desafíos diagnósticos y terapéuticos específicos, incluyendo la interpretación de pruebas y la presencia de enfermedades comórbidas. La levotiroxina sódica es el tratamiento preferido, pero su dosificación puede requerir ajustes cuidadosos. Un punto crítico es determinar cuándo iniciar el tratamiento. Conclusiones: El manejo del HTPG es un desafío debido a los cambios fisiológicos asociados con el envejecimiento y la presencia de enfermedades comórbidas. Se sugiere que futuras investigaciones se centren en establecer rangos de referencia de TSH específicos para la edad y determinar el umbral óptimo de TSH para iniciar el tratamiento en esta población.
Tétano Acidental no Departamento de Emergência: relato de caso
Authors: Nunes Silva Amanda Larissa , De Albuquerque Melo Vinícius Couto , Santos de Souza Lucas , Maia Semen Ana Clara , Oliveira Silva Danielle , dos Santos Lemes Henrique Stival 
Published: April 2024

O tétano é uma doença infecciosa aguda, que no Brasil possui uma incidência similar entre os sexos, embora seja mais frequentemente associada ao sexo masculino, devido a maior exposição a traumatismos. Essa doença ocorre pela ação de neurotoxinas produzidas pelo Clostridium tetani, que possuem tropismo pelas células do Sistema Nervoso Central e atuam bloqueando a neurotransmissão e a excitabilidade deste sistema. Este estudo visa relatar um caso do Departamento de Emergência de um hospital de Recife/PE. Trata-se de um paciente de 66 anos, negro, casado, morador da zona rural, agricultor, que dá entrada no serviço com queixa de dor lombar há 1 dia, refratária a analgésicos simples, anti-inflamatórios e opioides. Durante a avaliação médica, inicia quadro de sialorreia, sudorese intensa e movimentos espásticos generalizados. Em seguida, evolui com insuficiência respiratória e parada cardiorrespiratória. Retorna à circulação espontânea após 2 ciclos e é medicado com Diazepam IV, devido à persistência dos movimentos espásticos e padrão respiratório em gasping. Segue-se com intubação orotraqueal e conexão ao ventilador mecânico. Após saída do quadro agudo, familiares relataram história de lesão perfurante em joelho há 10 dias do aparecimento dos sintomas. É fechado o diagnóstico de tétano acidental grave e como conduta, faz-se administração de soro antitetânico (SAT) ou gamaglobulina (IGAT) e vacina dT. Faz-se metronidazol, diazepam IV, bloqueador neuromuscular contínuo e fentanil em bomba. Mantém-se a ventilação mecânica com uma PEEP de 10 e procede-se com transferência para UTI. Por se tratar de uma doença com diagnóstico clínico, mas que possui diversos diagnósticos diferenciais, a identificação precoce na emergência é uma medida fundamental para esta doença, assim como a instituição do tratamento adequado o mais breve possível.