bluuebunny/crossref_metadata_2025_split huggingface dataset:
Haptide‐coated collagen sponge as a bioactive matrix for tissue regeneration
Authors: Marx Gerard , Hotovely‐Salomon Anna , Levdansky Lila , Gaberman Elena , Snir Ganit , Sievner Zaki , Klauzner Yakir , Silberklang Melvin , Thomas Dolly , Hoffman Nataly , Luke Sunny , Lesnoy Daniel , Gorodetsky Raphael 
Published: August 2007

AbstractWe previously described a new class of conserved, cell adhesive (haptotactic) peptides, termed Haptides, based on sequences first identified in fibrinogen. Here, we describe a new biomaterial, Haptide‐coated Collagen, in which the carbodiimide reagent, EDC, was used to covalently couple a Haptide (preCγ), equivalent to the carboxy terminus of the fibrinogen γ chain, to a cross‐linked sponge composed of bovine collagen type I. The dose response of Haptide bound to collagen on cell attachment response reached a plateau at a concentration of 5–10 mg Haptide/g collagen. The Haptized‐collagen was more stable to 1N NaOH, with a degradation half‐time (T1/2) of 1.7 h, compared to 0.9 h for untreated control. Haptized collagen discs could be loaded with ∼30% more human dermal fibroblasts or bovine aortic endothelial cells than unmodified collagen discs (p < 0.001). After a proliferation phase, Haptized collagen discs contained ∼45% more fibroblasts than non‐Haptized discs (p < 0.01). Histological analysis following sub‐dermal implantation in rats indicated that at day 8, Haptized collagen sponge was less degraded than unmodified collagen sponge, attracted more endogenous fibroblasts with newly deposited collagen, and provoked less inflammatory or other adverse reactions. These results suggest potential clinical applications for Haptized collagen sponge for tissue regeneration, soft tissue augmentation, skin repair, and wound healing. © 2007 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater 2008
Identification of biomolecular conformations from incomplete torsion angle observations by hidden markov models
Authors: Fischer Alexander , Waldhausen Sonja , Horenko Illia , Meerbach Eike , Schütte Christof 
Published: August 2007

AbstractWe present a novel method for the identification of the most important conformations of a biomolecular system from molecular dynamics or Metropolis Monte Carlo time series by means of Hidden Markov Models (HMMs). We show that identification is possible based on the observation sequences of some essential torsion or backbone angles. In particular, the method still provides good results even if the conformations do have a strong overlap in these angles. To apply HMMs to angular data, we use von Mises output distributions. The performance of the resulting method is illustrated by numerical tests and by application to a hybrid Monte Carlo time series of trialanine and to MD simulation results of a DNA–oligomer.
Epithelial—mesenchymal and mesenchymal—epithelial transitions in carcinoma progression
Authors: Hugo Honor , Ackland M. Leigh , Blick Tony , Lawrence Mitchell G. , Clements Judith A. , Williams Elizabeth D. , Thompson Erik W. 
Published: August 2007

AbstractLike a set of bookends, cellular, molecular, and genetic changes of the beginnings of life mirror those of one of the most common cause of death—metastatic cancer. Epithelial to mesenchymal transition (EMT) is an important change in cell phenotype which allows the escape of epithelial cells from the structural constraints imposed by tissue architecture, and was first recognized by Elizabeth Hay in the early to mid 1980's to be a central process in early embryonic morphogenesis. Reversals of these changes, termed mesenchymal to epithelial transitions (METs), also occur and are important in tissue construction in normal development. Over the last decade, evidence has mounted for EMT as the means through which solid tissue epithelial cancers invade and metastasize. However, demonstrating this potentially rapid and transient process in vivo has proven difficult and data connecting the relevance of this process to tumor progression is still somewhat limited and controversial. Evidence for an important role of MET in the development of clinically overt metastases is starting to accumulate, and model systems have been developed. This review details recent advances in the knowledge of EMT as it occurs in breast development and carcinoma and prostate cancer progression, and highlights the role that MET plays in cancer metastasis. Finally, perspectives from a clinical and translational viewpoint are discussed. J. Cell. Physiol. 213: 374–383, 2007. © 2007 Wiley‐Liss, Inc.
Cell–matrix adhesion
Authors: Berrier Allison L. , Yamada Kenneth M. 
Published: August 2007

AbstractThe complex interactions of cells with extracellular matrix (ECM) play crucial roles in mediating and regulating many processes, including cell adhesion, migration, and signaling during morphogenesis, tissue homeostasis, wound healing, and tumorigenesis. Many of these interactions involve transmembrane integrin receptors. Integrins cluster in specific cell–matrix adhesions to provide dynamic links between extracellular and intracellular environments by bi‐directional signaling and by organizing the ECM and intracellular cytoskeletal and signaling molecules. This mini review discusses these interconnections, including the roles of matrix properties such as composition, three‐dimensionality, and porosity, the bi‐directional functions of cellular contractility and matrix rigidity, and cell signaling. The review concludes by speculating on the application of this knowledge of cell–matrix interactions in the formation of cell adhesions, assembly of matrix, migration, and tumorigenesis to potential future therapeutic approaches. J. Cell. Physiol. 213:565–573. © 2007 Wiley‐Liss, Inc.
Renal artery aneurysm in a solitary kidney
Authors: Cianci Rosario , Stivali Gilda , Zaccaria Alvaro , Barbano Biagio , Bianco Palma , Cerroni Franca 
Published: August 2007

AbstractA 55‐year‐old hypertensive female was referred for renal artery color Doppler examination because of a suspicion of renovascular hypertension. Renal artery aneurysm was occasionally detected at the distal portion of the artery in the single left kidney, without the presence of stenosis. An aneurysm was confirmed via magnetic resonance angiography and arteriographical examination. © 2007 Wiley Periodicals, Inc. J Clin Ultrasound, 2008
Antenatal diagnosis of a Morgagni hernia in the second trimester
Authors: Jain Krishan Kumar , Sen Jyotsna , Rathee Suresh Kanta , Saini Jitender 
Published: August 2007

AbstractMorgagni hernia is an uncommon type of congenital hernia that is rarely diagnosed antenatally. Herniation of the liver into the fluid‐filled pericardial sac resulting in a thoracic mass is a particularly rare form of Morgagni hernia; only 3 cases have been reported in the literature, all with a diagnosis made at 32 weeks' gestation or later. We report a case of Morgagni hernia diagnosed on antenatal sonography at 24 weeks' gestation. © 2007 Wiley Periodicals, Inc. J Clin Ultrasound, 2008
Sonographic appearance of a postpartum pyomyoma with gas production
Authors: Nguyen Quyen H. , Gruenewald Simon M. 
Published: August 2007

AbstractPyomyoma or suppurative leiomyoma is a potentially fatal complication of uterine leiomyomas. It is a rare condition with only a small number of reported cases since the era of antibiotics, and the descriptions of its sonographic appearance has been limited. We present a case of a pyomyoma associated with gas production, including a brief review of the reported sonographic features. © 2007 Wiley Periodicals, Inc. J Clin Ultrasound, 2008
Axon or dendrite? cell biology and molecular pathways for neuronal cell asymmetry
Authors: Kishi Masashi 
Published: August 2007

AbstractYoung neurons polarize by specializing axons and dendrites from immature neurites. After synapse formations, they transmit electrical activity along the axon‐dendrite axis, thereby working as functional units of the neural circuits. This axon‐dendrite asymmetry is referred to as neuronal polarity. Although a great number of cell biological studies in vitro had been performed, little was known about the molecular events that establish the polarity. In the last several years, rapid advancement in molecular and genetic studies has unraveled the multiple signaling pathways. This paper summarizes current perspectives on the cell and molecular biological mechanisms of the neuronal polarization, to clarify future directions in this growing research field. © 2007 Wiley‐Liss, Inc.
Reactions to psychological contract breach: a dual perspective
Authors: Chen Zhen Xiong , Tsui Anne S. , Zhong Lifeng 
Published: August 2007

AbstractThis study examined reactions to psychological contract breach from two separate perspectives, that is, employee's reactions to perceptions of employer breach and supervisor's reactions to perceptions of employee breach of the psychological contract. In addition to the main effects, we also hypothesized that the benevolence (or kindness) of the supervisor and the traditional values (or respect for authority) of the employee would attenuate the negative effects of psychological contract breach. We tested these hypotheses with a sample of 273 supervisor‐subordinate dyads from the People's Republic of China. The results showed that employer breach correlated negatively with employee outcomes of organizational commitment (OC), organizational citizenship behavior (OCB), and work performance, but this negative relationship was weaker for employees with traditional values. The results also demonstrated that employee breach correlated negatively with responses from the supervisor, in terms of the mentoring provided to the employee and the leader‐member exchange (LMX) quality. However, more benevolent supervisors reacted less negatively in terms of the mentoring than did the less benevolent supervisors. Implications for future research are offered. Copyright © 2007 John Wiley & Sons, Ltd.
Value of intensive follow‐up of patients after curative surgery for gastric carcinoma
Authors: Tan Ing Tuan , So Bok Yan Jimmy 
Published: August 2007

AbstractObjectiveMost clinicians perform surveillance after gastrectomy for gastric cancer. There is no consensus on the regimen, follow‐up interval and choice of investigations. This study aims to review the long‐term results of patients followed‐up in our institution after gastrectomy for gastric cancer.MethodsPatients with gastric carcinoma who had undergone gastrectomy between 1995 and 1998 were reviewed. The patients were assigned to either intensive or regular regimen based on the follow‐up they had undergone. Intensive regimen included routine physical examination, serum tumor markers, and the use of computed tomography (CT) scan of more than once per year in the follow‐up.ResultsA total of 102 patients were reviewed. Forty‐nine patients received intensive and 53 patients received regular follow‐up. Recurrences were detected earlier in the intensive group (11.5 vs. 19.2 months, P = 0.02). There was no difference in the length of survival in the two groups. Most recurrences (60%) were detected by CT scan.ConclusionsIntensive follow‐up after gastrectomy resulted in the earlier detection of recurrences. However, there was no survival benefit from this regimen. A regimen based on symptoms and physical examination is adequate for most patients. CT was the most useful investigation for detection of recurrences. J. Surg. Oncol. 2007;96:503–506. © 2007 Wiley‐Liss, Inc.
Radio‐guided nonpalpable metastatic lymph node localization in patients with recurrent thyroid cancer
Authors: Tükenmez Mustafa , Erbil Yeşim , Barbaros Umut , Dural Cem , Salmaslioglu Artür , Aksoy Deniz , Mudun Ayse , Özarmağan Selçuk 
Published: August 2007

AbstractThe detection of nonpalpable recurrent thyroid carcinoma has increased due to the use of imaging techniques in time. This report is to investigate whether preoperative injection of a radiotracer under ultrasound guidance is useful in nonpalpable recurrent thyroid carcinoma. The neck of two patients with recurrent thyroid carcinoma was scanned with the probe to localize the area of maximal radioactivity allowing appropriate location of the incision over the lesion. After the lymph nodes were removed, radioactivity was measured in the lesion bed to confirm the success of the dissection. In conclusion, the radio‐guided nonpalpable lesion localization technique can be performed safely for the detection and excision of metastatic foci. J. Surg. Oncol. 2007;96:534–538. © 2007 Wiley‐Liss, Inc.
Structures and Chiroptical Properties of Thermoresponsive Block Copolymers Containing L‐Proline Moieties
Authors: Mori Hideharu , Iwaya Hideyuki , Endo Takeshi 
Published: August 2007

AbstractAmino acid‐based block copolymers containing poly(A‐Pro‐OMe) have been synthesized by RAFT polymerization using the dithioester‐terminated poly(DMA) as a macro‐CTA. An amphiphilic block copolymer composed of polystyrene as a hydrophobic segment and poly(A‐Pro‐OMe) as a hydrophilic segment was also prepared using polystyrene as the macro‐CTA. The chiroptical properties of the block copolymer, poly(DMA)‐block‐poly(A‐Pro‐OMe), was evaluated by specific rotation, CD, and UV‐vis spectroscopy. The assembled structure of the block copolymer on a mica surface was characterized by SFM. Thermally induced phase separations of the random and block copolymers were also studied in aqueous solution.magnified image
Copolycondensation of Regular Functional Silane and Siloxane in Aqueous Emulsion Using B(C6F5)3 as a Catalyst
Authors: Longuet Claire , Joly‐Duhamel Christine , Ganachaud François 
Published: August 2007

AbstractThe copolycondensation of siloxane and silane bearing hydrido and methoxy groups, respectively, was carried out in a surfactant‐free aqueous emulsion, at room temperature and using B(C6F5)3 as a water‐tolerant Lewis acid. Several characterization techniques, including triple detection SEC, 29Si NMR and MALDI‐TOF, confirmed the generation of linear polymers (no macrocycles), of average molar masses ranging between 30 and 80 000 g · mol−1, and bearing silanol end‐groups. Colloidal evolution with time showed that a stable surfactant‐free emulsion was generated before some coalescence occurs by decreasing the content of silanol groups suspected to stabilize the emulsion. The kinetics of reaction was followed by SEC, and revealed the generation of small cycles, along with linear oligomers, before converting them to poly(dimethylsiloxane) chains. A tentative mechanism, where ring‐opening polymerization of the most stranded cyclosiloxane and polycondensation of polymer chains are considered, is proposed.magnified image
Augmented Lagrangian coordination for distributed optimal design in MDO
Authors: Tosserams S. , Etman L. F. P. , Rooda J. E. 
Published: August 2007

AbstractQuite a number of coordination methods have been proposed for the distributed optimal design of large‐scale systems consisting of a number of interacting subsystems. Several coordination methods are known to have numerical convergence difficulties that can be explained theoretically. The methods for which convergence proofs are available have mostly been developed for so‐called quasi‐separable problems (i.e. problems with individual subsystems coupled only through a set of linking variables, not through constraints and/or objectives). In this paper, we present a new coordination approach for multidisciplinary design optimization problems with linking variables as well as coupling objectives and constraints. Two formulation variants are presented, offering a large degree of freedom in tailoring the coordination algorithm to the design problem at hand. The first, centralized variant introduces a master problem to coordinate coupling of the subsystems. The second, distributed variant coordinates coupling directly between subsystems. Our coordination approach employs an augmented Lagrangian penalty relaxation in combination with a block coordinate descent method. The proposed coordination algorithms can be shown to converge to Karush–Kuhn–Tucker points of the original problem by using the existing convergence results. We illustrate the flexibility of the proposed approach by showing that the analytical target cascading method of Kim et al. (J. Mech. Design‐ASME 2003; 125(3):475–480) and the augmented Lagrangian method for quasi‐separable problems of Tosserams et al. (Struct. Multidisciplinary Opt. 2007, to appear) are subclasses of the proposed formulations. Copyright © 2007 John Wiley & Sons, Ltd.
Hydrophobic and self‐cleaning coatings
Authors: Dodiuk H. , Rios P. F. , Dotan A. , Kenig S. 
Published: August 2007

AbstractThe effects of nano and micro roughness as well as the chemical composition of surface treatments on hydrophobicity and self‐cleaning properties of the coated surfaces were studied theoretically and experimentally. Accordingly, relationships were derived between the interfacial adhesion strength of the liquid drop to a polymer surface of a given composition, the mass of the drop, the measured contact angles, and the sliding angle. To verify the proposed model various hydrophobic coatings having different surface nano and micro roughness were prepared using polycarbonate (PC) as a substrate.The surface treatment was based on fluoroalkylsilane. Roughness was introduced by means of Silica (micro) and polyhedral oligomeric silsesquioxane (POSS; nano) using a double morphology topography mimicking the Lotus leaf. In the case of optimal compositions and processing conditions, transparent ultra‐hydrophobic characteristics were obtained. In these cases the contact angle was close to 180° and the sliding angle was below 5°.These novel ultra‐hydrophobic surface coatings and the associated model could be used to develop and design surfaces for a variety of applications such as self‐cleaning glazing, repellent surfaces for threats from biochemicals, and anti‐icing of surfaces. Copyright © 2007 John Wiley & Sons, Ltd.
The impact of the concept of “Living Polymers” on material science
Authors: Levy M. 
Published: August 2007

AbstractThe concept of “Living Polymers” was first introduced in a short communication by M. Szwarc, M. Levy, and R. Milkovich in 1956 and is now widely used in the polymer literature. It led to the synthesis of monodisperse polymers, telechelic polymers, and block copolymers. Living polymerization has evolved in the last 50 years and new methods were developed for various other types of anionic, cationic, ring‐opening, and free radical polymerizations. The field has expanded tremendously and the term “controlled/living” polymerization is commonly used to cover all the methods. A few of the interesting developments in the area are described in this paper. Copyright © 2007 John Wiley & Sons, Ltd.
Flammability of polyamide 6 using the sulfamate system and organo‐layered silicate
Authors: Lewin Menachem , Zhang Jin , Pearce Eli , Gilman Jeffrey 
Published: August 2007

AbstractA high degree of flame retardancy (FR) of polyamide 6 (PA6) is obtained by adding low weight per cent NH2SO3NH4 (ammonium sulfamate, AS) and dipentaerythritol (Di). This result is preserved when 1 wt% of organo‐layered montmorillonite (OMMT) is dispersed in the AS + Di formulation. Increasing OMMT decreases these FR ratings. The surfaces of the gallery or exfoliated layers of OMMT adsorb and immobilize a part of AS + Di preventing its contribution to the FR reactions. The addition of the hydrophilic poly(vinylpyrrolidone) (PVP) partly restores the original FR ratings so a greater amount of AS + Di remains effective. The decrease in the high heat release rate (HRR) of the AS + Di containing PA6 by OMMT imparts to the PA6 lowered peak HRR (PHRR) and slower burning. Addition of pristine montmorillonite (MMT) up to 5 wt% does not decrease the UL‐94 V‐0 rating. The smaller surface area of the relatively large particles of the non‐colloidal pristine MMT adsorbs less AS + Di than OMMT. A straight line relationship was found between oxygen index (OI) values and ignition times in the cone calorimeter. The char resulting from combustion is composed mainly of MMT and some graphitic carbon. XRD found that the d(100) spacing for the clay in the final chars from burning was found to be 1.27 nm, corresponding to a 2θ peak of 7.0. No correlation between the size of the floccular structures on the char surface and the decrease in PHRR is found. Mechanistic considerations are presented. Copyright © 2007 John Wiley & Sons, Ltd.
Erratum: Polymeric materials for fuel cells: concise review of recent studies
Authors: Jagur‐Grodzinski Joseph 
Published: August 2007

AbstractPolym. Adv. Technol. 2007. DOI: 10.1002/pat.935The following changes should be recognised:On page 3 of the article 'The size of the hydrophilic clusters increased when they absorbed water. Subsequent ion exchange reaction with [Pt(NH3)4]Cl2 followed by reduction with 1‐pentanol at 125°C for 2 hr yielded Pt particles uniformly dispersed on SiO2‐PEM.On page 8 of the article 'The relation between the crossovers of methanol and its concentration in the anode compartment of DMFC's equipped with Nafion membranes was explored and its effect on the efficiency and power density generation was investigated.73–75Errors will be rectified prior to print publication.
An overview on gender, personality and mental health
Authors: Paris Joel 
Published: August 2007

AbstractPersonality traits are influenced by gender, and these differences are unlikely to be artefacts. Gender effects on traits also shape differences in the prevalence of common mental disorders, so that internalizing disorders are more common in females, while externalizing disorders are more common in males. Finally, gender effects influence the prevalence of specific personality disorders. These differences have clinical implications. Copyright © 2007 John Wiley & Sons, Ltd.
The impact of personality disorders on treatment outcome in bipolar disorder: A review
Authors: Bieling Peter J. , Green Sheryl M. , Macqueen Glenda 
Published: August 2007

AbstractBipolar disorder (BD) is a chronic psychiatric illness for which there are a number of efficacious and effective treatments. However, for many sufferers recovery is incomplete or tenuous. Factors associated with poor outcomes in the disorder are of special interest, and comorbidity of BD with personality disorder (PD) has been proposed as a possible predictor of poor outcome. We reviewed available studies (n = 12) in the literature that specifically assessed the impact of personality psychopathology on illness outcomes in BD including functioning, response to treatment and suicidality. Quality of methodology, assessment methods and number of participants in studies were highly variable. Despite these variations in study quality, the presence of a PD was robustly associated (usually medium size effects) with a worse outcome in BD. Patients with BD and a diagnosis of PD are more likely to be hospitalized, require more time to achieve symptom stabilization, have more chronic impairments in occupational and social functioning, are less compliant to medication, have greater levels of suicidality and utilize more psychiatric services than patients with BD alone. The implications of these findings for further research and clinical care in BD are discussed. Copyright © 2007 John Wiley & Sons, Ltd.