bluuebunny/crossref_metadata_2025_split huggingface dataset:
Book Reviews
Authors: Williams Ruth M. 
Published: March 2006

Oxford guide to behavioural experiments in cognitive therapy Edited by J. Bennett‐Levy, G. Butler, M. Fennell, A. Hackmann, M. Mueller & D. WestbrookOxford, UK: Oxford University Press, 2004, Pp. 461, £29.95, ISBN 0‐19‐8529155/8529163
Competition between Feedback Loops Underlies Normal and Pathological Dynamics in the Basal Ganglia
Authors: Leblois Arthur , Boraud Thomas , Meissner Wassilios , Bergman Hagai , Hansel David 
Published: March 2006

Experiments performed in normal animals suggest that the basal ganglia (BG) are crucial in motor program selection. BG are also involved in movement disorders. In particular, BG neuronal activity in parkinsonian animals and patients is more oscillatory and more synchronous than in normal individuals.We propose a new model for the function and dysfunction of the motor part of BG. We hypothesize that the striatum, the subthalamic nucleus, the internal pallidum (GPi), the thalamus, and the cortex are involved in closed feedback loops. The direct (cortex–striatum–GPi–thalamus–cortex) and the hyperdirect loops (cortex–subthalamic nucleus–GPi–thalamus–cortex), which have different polarities, play a key role in the model. We show that the competition between these two loops provides the BG–cortex system with the ability to perform motor program selection. Under the assumption that dopamine potentiates corticostriatal synaptic transmission, we demonstrate that, in our model, moderate dopamine depletion leads to a complete loss of action selection ability. High depletion can lead to synchronous oscillations. These modifications of the network dynamical state stem from an imbalance between the feedback in the direct and hyperdirect loops when dopamine is depleted.Our model predicts that the loss of selection ability occurs before the appearance of oscillations, suggesting that Parkinson's disease motor impairments are not directly related to abnormal oscillatory activity. Another major prediction of our model is that synchronous oscillations driven by the hyperdirect loop appear in BG after inactivation of the striatum.
Kinematic and Electromyographic Study of the Nociceptive Withdrawal Reflex in the Upper Limbs during Rest and Movement
Authors: Serrao Mariano , Pierelli Francesco , Don Romildo , Ranavolo Alberto , Cacchio Angelo , Currà Antonio , Sandrini Giorgio , Frascarelli Massimo , Santilli Valter 
Published: March 2006

This study set out to evaluate nociceptive withdrawal reflex (NWR) excitability and the corresponding mechanical response in the upper limbs during rest and movement. We used a three-dimensional motion analysis system and a surface EMG system to record, in 10 healthy subjects, the NWR in eight upper limb muscles and the corresponding mechanical response in two experimental conditions: rest and movement (reaching for, picking up, and moving a cylinder). The NWR was elicited through stimulation of the index finger with trains of pulses delivered at multiples of the pain threshold (PT). We correlated movement types (reach-to-grasp, grasp-and-lift), movement phases (acceleration, deceleration), and muscle activity types (shortening, lengthening, isometric) with the presence/absence of the NWR (reflex-muscle pattern), with NWR size values, and with the mechanical responses.At rest, when the stimulus was delivered at 4× PT, the NWR was present, in all muscles, in >90% of trials, and the mechanical response consisted of wrist adduction, elbow flexion, and shoulder anteflexion. At this stimulus intensity, during movement, the reflex-muscle pattern, reflex size, and mechanical responses were closely modulated by movement type and phase and by muscle activity type. We did not find, during movement, significant correlations with the level of EMG background activity.Our findings suggest that a complex functional adaptation of the spinal cord plays a role in modulating the NWR in the transition from rest to movement and during voluntary arm movement freely performed in three-dimensional space. Study of the upper limb NWR may provide a window onto the spinal neural control mechanisms operating during movement.
Vascular System Inspired 3D Electrolyte Network for High Rate and High Mass Loading Graphene Supercapacitor
Authors: Li Congming , Li Xiangming , Yang Qingzhen , Wu Lifeng , Wang Chao , Tian Hongmiao , Wang Chunhui , Chen Xiaoliang , Shao Jinyou 
Published: February 2024

AbstractHigh charge rate and high mass loading ability are of practical importance for high power and high volumetric performance supercapacitors but are always challenged by tortuous and sluggish ion diffusion in thick electrodes. Here, inspired by the hepatic vascular system, hierarchical 3D electrolyte networks are proposed to facilitate ion diffusion across laminar graphene films, resulting in a 14‐fold improved ion diffusion coefficient, better rate ability, and high mass loading ability for graphene supercapacitors. Such design enables graphene electrodes with high capacitance up to 236 F g−1, packing densities of 0.67–0.78 g cm−3 depending on structures; and core stack with 10 mg cm−2 mass loading exhibits a high energy density of 45.4 Wh L−1, which is among the state‐of‐the‐art graphene supercapacitors. This study provides a comprehensive investigation of structure‐related capacitive properties, guiding electrode design for high‐rate and high‐mass‐loading graphene supercapacitors. Moreover, such design also benefits solid‐state graphene supercapacitors by forming 3D gel electrolyte structures, which enable higher capacitance and better mechanical robustness, showing potential for flexible energy storage.
Facile Electrolytic (111)‐Textured Copper Foil for Dendrite‐Free Zinc Metal Batteries
Authors: Hao Zhimeng , Zhang Yufeng , Lu Yong , Hou Jinze , Liu Xinyi , Yan Zhenhua , Chen Jun 
Published: February 2024

AbstractAqueous Zn metal batteries are emerging as a promising candidate for the next‐generation largescale energy storage system due to their high safety, low lost, and eco‐friendliness. Nevertheless, their practical application is restricted by the uncontrollable Zn dendrite growth and the limited utilization of the Zn metal anode. Herein, a room temperature electrodeposition strategy based on an optimized rate relationship between the diffusion and consumption of Cu2+ to prepare a (111)‐textured Cu current collector for the construction of the dendrite‐free Zn metal anode with high reversibility is developed. Attributed to the high lattice match between the (002) facet of Zn with the (111) facet of Cu, the deposition of Zn along its [001] orientation is achieved on the (111)‐textured Cu. The (002) facets horizontally aligned with the current collector endow Zn with the dendrite‐free planar construction and superior corrosion resistance, resulting in a high reversibility with a long life‐span over 2186 cycles. Impressively, the resultant Zn anodes can stabilize the operation of pouch cells with an extremely demanding negative‐to‐positive capacity ratio of 2. This work provides a new avenue for the development of the current collectors for the low‐cost sustainable energy storage.
Polymeric Conductive Adhesive‐Based Ultrathin Epidermal Electrodes for Long‐Term Monitoring of Electrophysiological Signals
Authors: Shin Joo Hwan , Choi Ji Yeong , June Keonuk , Choi Hyesu , Kim Tae‐il 
Published: February 2024

AbstractElectrophysiology, exploring vital electrical phenomena in living organisms, anticipates broader integration into daily life through wearable devices and epidermal electrodes. However, addressing the challenges of the electrode durability and motion artifacts is essential to enable continuous and long‐term biopotential signal monitoring, presenting a hurdle for its seamless implementation in daily life. To address these challenges, an ultrathin polymeric conductive adhesive, poly(3,4‐ethylenedioxythiophene): poly(styrenesulfonate)/polyvinyl alcohol/d‐sorbitol (PPd) electrode with enhanced adhesion, stretchability, and skin conformability, is presented. The skin conformability and stability of electrodes is designed by theoretical criteria obtained by mechanical analysis. Thus, impedance stability is obtained over 1‐week of daily life, and the PPd electrode addresses the challenges related to durability during prolonged usage. Proving stability in electromyography (EMG) signals during high‐intensity exercise, the wireless PPd measurement system exhibits high signal‐to‐noise ratio (SNR) signals even in situations involving significant and repetitive skin deformation. Throughout continuous 1 week‐long electrocardiogram (ECG) monitoring in daily life, the system consistently preserves signal quality, underscoring the heightened durability and applicability of the PPd measurement system.
Self‐Assembly PbS Quantum Dot‐Conjugated Polymer Hybrid‐Layered Phototransistor Enables SWIR Photodetection with High Detectivity
Authors: Jiang Zhixiang , Gao Yuanhong , Hui Wei , Feng Yang , Xu Meili , Li Jinxiong , Jiang Feng , Zhang Xiaopeng , Wang Jianing , Meng Hong , Huang Wei 
Published: February 2024

AbstractLead sulfide colloid quantum dots (PbS QDs) offer great opportunities to revolutionize large‐area short‐wave infrared (SWIR) detection technologies due to high absorption coefficients and spectral selectivity. However, a critical issue for QDs‐based SWIR detectors is high dark current noise due to thermal carriers and the large amounts of surface defect states induced by the ligand exchange process, which hinders the improvement of the room temperature detectivity and linear dynamic range. Herein, it is demonstrated that these dilemmas can be overcome by adopting a novel hybrid‐layered phototransistor device architecture composed of a self‐assembly high‐mobility organic conduction channel and a bulk heterojunction infrared absorber containing PbS QDs as sensitizers. Strong photo absorption in the photoactive layer creates photogenerated charges that are transferred to the conduction channel, where they recirculate many times due to the long trapped‐electron lifetime in the photoactive layer and the high carrier mobility of the channel. Therefore, low dark current noise and high photoconductive gain are achieved by both electrical gating and photodoping for carrier‐density modulation of phototransistors. Finally, an optimized SWIR phototransistor device with a low room‐temperature dark current of 7 pA and a high detectivity of 8 × 1012 Jones under 1650 nm light illumination is demonstrated.
Soybean test weight in relation to genotype, environment, and genotype × environment interaction in the Southern United States
Authors: Koebernick Jenny , Gillen Anne M. , Fett Robert , Patel Sejal , Fallen Ben , Pantalone Vince , Shannon Grover , Li Zenglu , Scaboo Andrew , Schapaugh William , Mian Rouf , Read Quentin D. 
Published: February 2024

AbstractTest weight (TW) is a unit of bulk density that is influenced by several factors, including both genetics and environment. A subset of the trials in the Uniform Soybean Tests—Southern States was used to correlate seed composition traits of oil and protein percentages, and seed weight (SW) with TW to investigate the interaction of these traits in multi‐environments for four different maturity group (MG) tests. The results indicate that environment (location and year combination) had a larger impact on TW than genetic effect in all MG tests. This difference was greater in the earlier MGs, compared to MG VI and MG VII. In all tests across four MGs, the genotype interaction with environment effect was significant, but practically was not as important as genotype or environment effects. Significant negative correlations between TW and SW (MG V, VI, and VII tests), and TW and oil (MG V and VI tests) were observed but not consistent in all environments within these tests. TW and protein correlations were inconsistent with a negative relationship in MG V but a positive relationship in MG VII. As anticipated, the inconsistencies in the relationships across MGs for TW and seed composition traits suggest that selection strategies for improving TW will differ across soybean breeding programs. In the future, a similar study using a diverse panel of cultivars that do not change from year to year may shed more light on the influence of seed composition and environmental conditions on TW.
Assessing relationships of cover crop biomass and nitrogen content to multispectral imagery
Authors: Miller Jarrod O. , Shober Amy L. , Taraila Jamie 
Published: February 2024

AbstractCover crops provide valuable roles in sustainable agriculture, provided they produce enough biomass. To accurately measure their services to field management, spatial estimates would be useful to producers. This study used multispectral drone imagery to produce maps of normalized difference vegetation index (NDVI), normalized difference red edge index (NDRE), and a digital surface model (DSM) of cover crop plots on sandy, Mid‐Atlantic soils. Cover crops included cereal rye (Secale cereale), mixtures of rye and crimson clover (Trifolium incarnatum), and mixtures of rye and hairy vetch (Vicia villosa). Their biomass was sampled in the spring of 2019, 2020, and 2021, dried, weighed, and analyzed for total nitrogen (N) content. Measurements of NDVI became saturated (i.e., reached a linear plateau) at 3.86 Mg biomass ha−1, NDRE at 5.72 Mg biomass ha−1, and the DSM at 5.11 Mg biomass ha−1. The measured N content became saturated at 80.9, 139.1, and 75 kg N ha−1 for NDVI, NDRE, and the DSM, respectively. Based on log transformations, NDVI was a stronger predictor of biomass and N, but not C:N. The NDRE was important for biomass, N, and C:N, while the DSM interactions with cover crop species helped predict both the N content and C:N of cover crop tissues. Accumulated growing degree days was important as an individual variable for biomass and N and as an interaction with cover crop species.
Bothersome symptoms at midlife in relation to body fat percentage
Authors: Gerber L. M. , Whitcomb B. W. , Verjee M. A. , Sievert L. L. 
Published: February 2024

AbstractObjectivesIncreasing obesity has been associated with a higher frequency of symptoms at midlife. Bothersomeness represents an important measure of perceived symptom severity, but has received relatively little consideration, and relationships between symptom bothersomeness and obesity are not known. We evaluated the association between body fat percentage (%BF) and the bothersomeness of symptoms at midlife.MethodsThis cross‐sectional study included women aged 40–60 in Qatar (n = 841). Participants reported frequency and bothersomeness of midlife symptoms hypothesized to be related to body composition. Initially, we characterized the relationship between continuous %BF and presence (yes/no) and bothersomeness (yes/no) for each symptom using restricted cubic spline (RCS) models to test nonlinearity. Subsequently, we used multinomial logistic regressions to evaluate associations between %BF and multilevel symptom outcomes, where categories were: (a) no symptoms or bother, (b) symptoms without bothersomeness, and (c) symptoms with bothersomeness.ResultsThe highest frequency of bothersomeness was reported for aches/stiffness in joints (51%), followed by trouble sleeping (34%), night sweats (21%), urinary incontinence (18%), hot flashes (16%), and shortness of breath (15%). In unadjusted multinomial logistic regressions, aches/stiffness in joints with and without bothersomeness had the same significant relationship with %BF. Bothersome night sweats, urinary incontinence, and hot flashes were significantly associated with %BF (p < .05), but those same symptoms without bothersomeness were not significantly associated with %BF.ConclusionsOur findings suggest that bothersomeness is an important variable that tracks with body fat and gives different information than report of the presence/absence of a symptom alone.
3q29 duplications: A cohort of 46 patients and a literature review
Authors: Massier Marie , Doco‐Fenzy Martine , Egloff Matthieu , Le Guillou Xavier , Le Guyader Gwenaël , Redon Sylvia , Benech Caroline , Le Millier Karine , Uguen Kevin , Ropars Juliette , Sacaze Elise , Audebert‐Bellanger Séverine , Apetrei Andreea , Molin Arnaud , Gruchy Nicolas , Vincent‐Devulder Aline , Spodenkiewicz Marta , Jacquin Clémence , Loron Gauthier , Thibaud Marie , Delplancq Geoffroy , Brisset Sophie , Lesieur‐Sebellin Marion , Malan Valérie , Romana Serge , Rio Marlène , Marlin Sandrine , Amiel Jeanne , Marquet Valentine , Dauriat Benjamin , Moradkhani Kamran , Mercier Sandra , Isidor Bertrand , Arpin Stéphanie , Pujalte Mathilde , Jedraszak Guillaume , Pebrel‐Richard Céline , Salaun Gaëlle , Laffargue Fanny , Boudjarane John , Missirian Chantal , Chelloug Nora , Toutain Annick , Chiesa Jean , Keren Boris , Mignot Cyril , Gouy Evan , Jaillard Sylvie , Landais Emilie , Poirsier Céline 
Published: February 2024

AbstractDuplications of the 3q29 cytoband are rare chromosomal copy number variations (CNVs) (overlapping or recurrent ~1.6 Mb 3q29 duplications). They have been associated with highly variable neurodevelopmental disorders (NDDs) with various associated features or reported as a susceptibility factor to the development of learning disabilities and neuropsychiatric disorders. The smallest region of overlap and the phenotype of 3q29 duplications remain uncertain. We here report a French cohort of 31 families with a 3q29 duplication identified by chromosomal microarray analysis (CMA), including 14 recurrent 1.6 Mb duplications, eight overlapping duplications (>1 Mb), and nine small duplications (<1 Mb). Additional genetic findings that may be involved in the phenotype were identified in 11 patients. Focusing on apparently isolated 3q29 duplications, patients present mainly mild NDD as suggested by a high rate of learning disabilities in contrast to a low proportion of patients with intellectual disabilities. Although some are de novo, most of the 3q29 duplications are inherited from a parent with a similar mild phenotype. Besides, the study of small 3q29 duplications does not provide evidence for any critical region. Our data suggest that the overlapping and recurrent 3q29 duplications seem to lead to mild NDD and that a severe or syndromic clinical presentation should warrant further genetic analyses.
De novo variants predicting haploinsufficiency for DIP2C are associated with expressive speech delay
Authors: Ha Thoa , Morgan Angela , Bartos Meghan N. , Beatty Katelyn , Cogné Benjamin , Braun Dominique , Gerber Céline B. , Gaspar Harald , Kopps Anna M. , Rieubland Claudine , Hurst Anna C. E. , Amor David J. , Nizon Mathilde , Pasquier Laurent , Pfundt Rolph , Reis André , Siu Victoria Mok , Tessarech Marine , Thompson Michelle L. , Vincent Marie , de Vries Bert B. A. , Walsh Matthew B. , Wechsler Stephanie Burns , Zweier Christiane , Schnur Rhonda E. , Guillen Sacoto Maria J. , Margot Henri , Masotto Barbara , Palafoll Maria Irene Valenzuela , Nawaz Urwah , Voineagu Irina , Slavotinek Anne 
Published: February 2024

AbstractThe disconnected (disco)‐interacting protein 2 (DIP2) gene was first identified in D. melanogaster and contains a DNA methyltransferase‐associated protein 1 (DMAP1) binding domain, Acyl‐CoA synthetase domain and AMP‐binding sites. DIP2 regulates axonal bifurcation of the mushroom body neurons in D. melanogaster and is required for axonal regeneration in the neurons of C. elegans. The DIP2 homologues in vertebrates, Disco‐interacting protein 2 homolog A (DIP2A), Disco‐interacting protein 2 homolog B (DIP2B), and Disco‐interacting protein 2 homolog C (DIP2C), are highly conserved and expressed widely in the central nervous system. Although there is evidence that DIP2C plays a role in cognition, reports of pathogenic variants in these genes are rare and their significance is uncertain. We present 23 individuals with heterozygous DIP2C variants, all manifesting developmental delays that primarily affect expressive language and speech articulation. Eight patients had de novo variants predicting loss‐of‐function in the DIP2C gene, two patients had de novo missense variants, three had paternally inherited loss of function variants and six had maternally inherited loss‐of‐function variants, while inheritance was unknown for four variants. Four patients had cardiac defects (hypertrophic cardiomyopathy, atrial septal defects, and bicuspid aortic valve). Minor facial anomalies were inconsistent but included a high anterior hairline with a long forehead, broad nasal tip, and ear anomalies. Brainspan analysis showed elevated DIP2C expression in the human neocortex at 10–24 weeks after conception. With the cases presented herein, we provide phenotypic and genotypic data supporting the association between loss‐of‐function variants in DIP2C with a neurocognitive phenotype.
Benzannulated Double Aza[9]helicenes: Synthesis, Structures, and (Chir)optical Properties
Authors: Matsuo Yusuke , Gon Masayuki , Tanaka Kazuo , Seki Shu , Tanaka Takayuki 
Published: February 2024

AbstractA benzannulated double aza[9]helicene 1 was successfully synthesized via a one‐pot oxidative fusion reaction. 1 was derivatized to N‐alkylated double aza[9]helicene 1‐Et and 1‐Bu, whose structures were determined by X‐ray diffraction analysis. 1‐Et and 1‐Bu exhibited red‐shifted absorption and fluorescence spectra compared to single aza[9]helicene. The double aza[9]helicenes were expected to have two different conformers. Consistent with solid‐state structure, the chiral‐isomer was estimated to be more stable by 16 kcal/mol relative to meso‐isomer. Indeed, enantiomers of 1‐Et and 1‐Bu were optically resolved by HPLC and showed mirror‐imaged CD and CPL spectra with the CPL brightness up to 19.2 M−1cm−1 for 1‐Bu.
‘All about the NHS and what about the rest of us?’: Exploring how low‐paid health and social care workers construct key stakeholders and account for the UK's response to the COVID‐19 pandemic
Authors: Buckley Tieran , Carr Philippa 
Published: February 2024

AbstractGood practice on disaster response emphasises the importance of leadership and cohesive group identities. The COVID‐19 pandemic provided an opportunity to explore how low‐paid health and social care workers (HSCWs) accounted for the UK government's response, given worker's limited resources and disproportionate impact on their lives. Thirteen semi‐structured interviews took place with low‐paid HSCWs in England. Interviews were analysed using critical reflexive thematic analysis that is influenced by discursive psychology and membership categorisation analysis to explore the construction of identities and how they are used to account for the pandemic response. Three themes were generated from the data: (1) ‘They kind of knew what was coming’: UK government slow to react to pandemic developments; (2) ‘the right thing kept changing every five minutes: Frustrations with changing guidelines and (3) ‘all about the NHS and what about the rest of us?’: Private sector HSCWs presented as inferior. This research highlights the importance of addressing the minimisation of low‐paid HSCWs through communications and access to material resources. There is a need to address economic disparities within the social care sector and for the UK government to plan future crisis management with all frontline staff at the forefront to form a collective identity.