bluuebunny/crossref_metadata_2025_split huggingface dataset:
Modulation of starch synthesis in Arabidopsis via phytochrome B‐mediated light signal transduction
Authors: Shi Qingbiao , Xia Ying , Xue Na , Wang Qibin , Tao Qing , Li Mingjing , Xu Di , Wang Xiaofei , Kong Fanying , Zhang Haisen , Li Gang 
Published: February 2024

ABSTRACTStarch is a major storage carbohydrate in plants and is critical in crop yield and quality. Starch synthesis is intricately regulated by internal metabolic processes and external environmental cues; however, the precise molecular mechanisms governing this process remain largely unknown. In this study, we revealed that high red to far‐red (high R:FR) light significantly induces the synthesis of leaf starch and the expression of synthesis‐related genes, whereas low R:FR light suppress these processes. Arabidopsis phytochrome B (phyB), the primary R and FR photoreceptor, was identified as a critical positive regulator in this process. Downstream of phyB, basic leucine zipper transcription factor ELONGATED HYPOCOTYL5 (HY5) was found to enhance starch synthesis, whereas the basic helix‐loop‐helix transcription factors PHYTOCHROME INTERACTING FACTORs (PIF3, PIF4, and PIF5) inhibit starch synthesis in Arabidopsis leaves. Notably, HY5 and PIFs directly compete for binding to a shared G‐box cis‐element in the promoter region of genes encoding starch synthases GBSS, SS3, and SS4, which leads to antagonistic regulation of their expression and, consequently, starch synthesis. Our findings highlight the vital role of phyB in enhancing starch synthesis by stabilizing HY5 and facilitating PIFs degradation under high R:FR light conditions. Conversely, under low R:FR light, PIFs predominantly inhibit starch synthesis. This study provides insight into the physiological and molecular functions of phyB and its downstream transcription factors HY5 and PIFs in starch synthesis regulation, shedding light on the regulatory mechanism by which plants synchronize dynamic light signals with metabolic cues to module starch synthesis.
The global leadership into malnutrition criteria reveals a high percentage of malnutrition which influences overall survival in patients with gastroenteropancreatic neuroendocrine tumours
Authors: Clement Dominique S. V. M. , van Leerdam Monique E. , Tesselaar Margot E. T. , Cananea Elmie , Martin Wendy , Weickert Martin O. , Sarker Debashis , Ramage John K. , Srirajaskanthan Rajaventhan 
Published: February 2024

AbstractPatients with neuroendocrine tumours located in the gastroenteropancreatic tract (GEP‐NETs) and treatment with somatostatin analogues (SSA's) are at risk of malnutrition which has been reported previously evaluating weight loss or body mass index (BMI) only. The global leadership into malnutrition (GLIM) criteria include weight loss, BMI, and sarcopenia, for diagnosing malnutrition. These GLIM criteria have not been assessed in patients with GEP‐NETs on SSA. The effect of malnutrition on overall survival has not been explored before. The aim of this study is to describe the presence of malnutrition in patients with GEP‐NET on SSA based on the GLIM criteria and associate this with overall survival. Cross‐sectional study screening all patients with GEP‐NETs on SSA's for malnutrition using the GLIM criteria. Body composition analysis for sarcopenia diagnosis were performed. Bloods including vitamins, minerals, and lipid profile were collected. Overall survival since the date of nutrition screening was calculated. Uni‐ and multivariate Cox regression analysis were performed to identify malnutrition as risk factor for overall survival. A total of 118 patients, 47% male, with median age 67 years (IQR 56.8–75.0) were included. Overall, malnutrition was present in 88 patients (75%); based on low BMI in 26 (22%) patients, based on weight loss in 35 (30%) patients, and based on sarcopenia in 83 (70%) patients. Vitamin deficiencies were present for vitamin D in 64 patients (54%), and vitamin A in 29 patients (25%). The presence of malnutrition demonstrated a significantly worse overall survival (p‐value = .01). In multivariate analysis meeting 2 or 3 GLIM criteria was significantly associated with worse overall survival (HR 2.16 95% CI 1.34–3.48, p‐value = .002). Weight loss was the most important risk factor out of the 3 GLIM criteria (HR 3.5 95% CI 1.14–10.85, p‐value = .03) for worse overall survival. A high percentage (75%) of patients with GEP‐NETs using a SSA meet the GLIM criteria for malnutrition. Meeting more than 1 GLIM criterium, especially if there is weight loss these are risk factors for worse overall survival.
Reproductive binds: The gendered economy of debt in a Syrian refugee farmworker camp
Authors: Sajadian China 
Published: February 2024

AbstractBased on 18 months of ethnographic fieldwork at the Lebanese‐Syrian border, this article analyses the gendered economy of debt among Syrian farmworkers in shawish camps, which have for decades supplied the largest and lowest paid seasonal labour force within Lebanon's food system. In turn, it traces how debt relations in these camps expanded as hundreds of thousands of Syrians sought long‐term refuge in Lebanon throughout the war in Syria (2011 to present). Revisiting classic and contemporary agrarian questions of debt from a feminist social reproduction perspective, the article charts how this debt system ultimately deepened the burdens of feminized work in the fields and in the home. Emblematic of debt's ‘reproductive binds’, these camps offer broader insights into how debt reconfigures gendered and generational divisions of labour within displaced agricultural families—and how these conditions are negotiated, contested and reproduced in daily life.
KTWS (Klippel‐Trenaunay‐Weber syndrome): A systematic presentation of a rare disease
Authors: Mofarrah Ramina , Mofarrah Ramin , Gooranorimi Peyman , Emadi Sadaf , Aski Sueshianth Ghobadi 
Published: February 2024

AbstractBackgroundKlippel‐Trenaunay‐Weber syndrome (KTWS) is a rare disease with a wide range of manifestations. KTWS is characterized by a clinical triad of varicosities of the extremities, cutaneous vascular malformations, and hypertrophy of soft tissues and long bones. The diagnosis is made clinically supplemented with magnetic resonance imaging and computed tomography.AimHereby we aim to highlight the significance of the possible life‐threatening first‐time presentations associated with the GI system in previously undiagnosed KTWS patients.PatientWe report the case of a 47‐year‐old male with KTWS, who presented with various symptoms such as rectorrhagia since childhood, digestive problems and abnormal lateral vascular malformations of the left buttock which extended all the way to the leg, vascular malformations of the left fourth and fifth toes as well as soft tissue swelling of the left foot. There was no evidence of other clinical presentations. The patient was hospitalized with severe rectorrhagia and a hemoglobin level of 3/9. Physical examination revealed a blood pressure of 85/55 and pulse rate of 115. Ruptured aneurysm of the superior mesenteric artery was found on angiography and subsequently treated with embolization. Dermatologic evaluation showed pitting edema of the left leg and foot and multiple vascular lesions. Thus a diagnosis of KTWS was established. Pulsed dye laser therapy and compression bandage was performed for the patient. The patient's follow‐up was done 3 months after discharge for which the patient was again consulted by a dermatologist and gastroenterologist. Lymphedema of the left leg had improved to a great extend so treatment with compression bandage was continued. Colonoscopy was repeated for the patient to evaluate and control possible active sources of bleeding, due to potential life‐threating complications.ResultsAccording to previous findings, there have been few case reports of KTWS presenting with gastrointestinal manifestations, fewer of which have covered acute life‐threatening bleedings associated with this system.
Redistribution with needs
Authors: Martínez Ricardo , Moreno‐Ternero Juan D. 
Published: February 2024

AbstractWe take an axiomatic approach to study redistribution problems when agents report income and needs. We formalize axioms reflecting ethical and operational principles such as additivity, impartiality and individual rationality. Different combinations of those axioms characterize three focal rules (laissez faire, full redistribution, and need‐adjusted full redistribution) as well as compromises among them. We also uncover the structure of those compromises exploring the Lorenz dominance criterion as well as majority voting. Our analysis provides an axiomatic justification for a linear income tax system. We conclude our analysis resorting to Eurostat's Household Budget Survey from where we illustrate the different redistribution patterns accounting for needs across European countries.
Nurses' career choice and satisfaction with mental health transition‐to‐practice programs: A cross sectional study
Authors: Alexander Louise , Toomey Nigel , Foster Kim 
Published: February 2024

Accessible summaryWhat Is Known on the Subject?

There are significant issues recruiting nurses into mental health due to several reasons such as dilution of curriculum, and mental health being an unpopular career choice

Transition programs provide nurses entering mental health with orientation, academic and clinical skills, and knowledge.

What the Paper Adds to Existing Knowledge?

Transition programs need to be nuanced to specialty areas (e.g. community) to ensure nurses are given the support necessary to remain working in the field.

Many nurses choose to work in mental health due to a lived or personal experience and as such strengthening wellbeing supports for transitioning nurses is an important role in retention.

What Are the Implications for Practice?

Tailored transition programs can help strengthen mental health nurse role clarity, and support staff retention.

Transition programs should be a segue to formal postgraduate studies in mental health nursing to strengthen professional practice and retention of nurses.

AbstractIntroductionGlobally, there are consistent issues recruiting staff into the mental health nursing workforce. In Australia, recent efforts to expand the workforce include recruitment of a wider range of nurses in addition to new graduates into mental health transition‐to‐practice programs. Understanding the career motivations of nurses entering the field is an important element of recruitment and retention.AimTo describe nurses' satisfaction with their mental health transition program and identify factors influencing their choice of mental health as a career.MethodsAn online cross‐sectional survey with questions on program satisfaction and career choice was responded to by n = 55 enrolled and registered nurses in a mental health transition program.ResultsNurses reported overall high satisfaction with their program and identified increased time release for professional development and being supernumerary as necessary to support role development. Almost 25% of nurses reported personal experience of mental illness as an influence in choosing a mental health career.DiscussionMental health transition programs are important in recruitment and retention and need to be tailored to the needs of a wide range of nurses and include support for staff wellbeing.Implications for PracticeTailored transition programs can help strengthen role clarity, and support staff retention.
Citizen security revisited: Whose security/ies are we talking about?
Authors: Marchand Marianne H. 
Published: February 2024

AbstractThis article addresses two issues related to citizen security and its developments in Mexico. First, it analyzes the limits of citizen security in terms of its exclusions and marginalizations as they particularly affect women and migrants. It is argued that citizen security policy does not capture the multilayered security concerns that affect women. As programs of citizen security are primarily directed at public spaces, gender‐based violence, in particular domestic violence, is not included in its conceptualization. Second, migrants in transit are being excluded from citizen security for being noncitizens and thus “underserving subjects.” Moreover, citizen security tends to be place‐bound as it is directed at the community level, while migrants are persons in situations of mobility and therefore escape place‐bound initiatives. The second part of this article focuses on how the current militarization of Mexico's security policy has affected citizen security. It finds that this militarization has deprioritized citizen security, affecting women and migrants in particular.
Real‐time displacement measurement for long‐span bridges using a compact vision‐based system with speed‐optimized template matching
Authors: Wang Miaomin , Xu Fuyou , Koo Ki‐Young , Wang Pinqing 
Published: February 2024

AbstractThis paper introduces a new accelerating algorithm, efficient match slimmer (EMS), specifically designed to lighten computational loads of sophisticated template matching algorithms, enabling these algorithms to be effectively run on single‐board computers. Utilizing EMS in conjunction with a robust template matching algorithm, we have developed Raspberry Vision—a compact, cost‐effective, and real‐time vision‐based system. Its compactness and portability facilitate a practical measurement strategy that not only minimizes the camera‐to‐target distance but also simplifies the camera calibration process in bridge displacement monitoring, thereby enhancing measurement accuracy. The performance of the system is estimated on two operational suspension bridges. The results demonstrate that Raspberry Vision, equipped with the measurement strategy, can significantly improve the measurement accuracy in the long‐span bridge test and is also suitable for cross‐sea bridge measurements.
Exogenous application of pectin triggers stomatal closure and immunity in Arabidopsis
Authors: Zhang Cheng , Tetteh Charles , Luo Sheng , Jin Pinyuan , Hao Xingqian , Sun Min , Fang Nan , Liu Yingjun , Zhang Huajian 
Published: February 2024

AbstractPectin has been extensively studied in animal immunity, and exogenous pectin as a food additive can provide protection against inflammatory bowel disease. However, the utility of pectin to improve immunity in plants is still unstudied. Here, we found exogenous application of pectin triggered stomatal closure in Arabidopsis in a dose‐ and time‐dependent manner. Additionally, pectin activated peroxidase and nicotinamide adenine dinucleotide phosphate (NADPH) oxidase to produce reactive oxygen species (ROS), which subsequently increased cytoplasmic Ca2+ concentration ([Ca2+]cyt) and was followed by nitric oxide (NO) production, leading to stomatal closure in an abscisic acid (ABA) and salicylic acid (SA) signalling‐dependent mechanism. Furthermore, pectin enhanced the disease resistance to Pseudomonas syringae pv. tomato DC3000 (Pst DC3000) with mitogen‐activated protein kinases (MPKs) MPK3/6 activated and upregulated expression of defence‐responsive genes in Arabidopsis. These results suggested that exogenous pectin‐induced stomatal closure was associated with ROS and NO production regulated by ABA and SA signalling, contributing to defence against Pst DC3000 in Arabidopsis.
Biomechanical Research of Three Parallel Cannulated Compression Screws in Oblique Triangle Configuration for Fixation of Femoral Neck Unstable Fractures
Authors: Zhang Ru‐Yi , Zhang Wu‐Peng , Yang Guang‐Min , Wang Dao‐Feng , Su Peng , Zhang Yi , Nie Shao‐Bo , Li Jia , Zhao Zhe , Li Jian‐Tao , Zhang Li‐Cheng , Tang Pei‐Fu 
Published: February 2024

ObjectiveSurgical treatment with internal fixation, specifically percutaneous fixation with three cannulated compression screws (CCSs), is the preferred choice for young and middle‐aged patients. The mechanical advantage of the optimal spatial configuration with three screws provides maximum dispersion and cortical support. We suspect that the spatial proportion of the oblique triangle configuration (OTC) in the cross‐section of the femoral neck isthmus (FNI) may significantly improve shear and fatigue resistance of the fixed structure, thereby stabilizing the internal fixation system in femoral neck fracture (FNF). This study aims to explore the mechanical features of OTC and provide a mechanical basis for its clinical application.MethodsTwenty Sawbone femurs were prepared as Pauwels type III FNF models and divided equally into two fixation groups: OTC and inverted equilateral triangle configuration (IETC). Three 7.3 mm diameter cannulated compression screws (CCSs) were used for fixation. The specimens of FNF after screw internal fixation were subjected to static loading and cyclic loading tests, respectively, with five specimens for each test. Axial stiffness, 5 mm failure load, ultimate load, shear displacement, and frontal rotational angle of two fragments were evaluated. In the cyclic loading test, the load sizes were 700 N, 1400 N, and 2100 N, respectively, and the fracture end displacement was recorded. Results were presented as means ± SD. Data with normal distributions were compared by the Student's t test.ResultsIn the static loading test, the axial stiffness, ultimate load, shear displacement, and frontal rotational angle of two fragments were (738.64 vs. 620.74) N/mm, (2957.61 vs. 2643.06) N, (4.67 vs. 5.39) mm, and (4.01 vs. 5.52)° (p < 0.05), respectively. Comparison between the femoral head displacement after 10,000 cycles of 700N cyclic loading and total displacement after 20,000 cycles of 700–1400N cyclic loading showed the OTC group was less than the IETC group (p < 0.05). A comparison of femoral head displacement after 10,000 cycles of 1400N and 2100N cycles and total displacement after 30,000 cycles of 700–2100N cycles showed the OTC group was less than another group, but the difference was not significant (p > 0.05).ConclusionWhen three CCSs are inserted in parallel to fix FNF, the OTC of three screws has obvious biomechanical advantages, especially in shear resistance and early postoperative weight‐bearing, which provides a mechanical basis for clinical selection of ideal spatial configuration for unstable FNF.
Drought responses and carbon allocation strategies of poplar with different leaf maturity
Authors: Yao Yuan , Xia Linchao , Yang Le , Liu Ruixuan , Zhang Sheng 
Published: February 2024

AbstractLeaf characteristics can reflect the adaptation of trees to drought stress. However, the effect of leaf maturity on drought stress has been neglected, leading to uncertainty in inferring individual tree responses to drought from leaves. The allocation strategy of photosynthetic carbon between leaf organs (fully expanded young and old leaves) under drought stress remains unclear. Poplar is a diverse and widespread tree species in arid and semi‐arid regions. Here, three poplar genotypes (Populus cathayana, P. × euramericana ‘Nanlin 895’, and P. alba × P. tremula var. glandulosa) were selected and exposed to different watering regimes. The responses and carbon allocation strategies of leaves with different maturity to drought were investigated using a combination of leaf traits and 13C pulse labelling technique. The results showed that (1) fully expanded young leaves had better osmotic regulation and antioxidant capacity than aged leaves under drought stress. (2) Aged leaves acted as a carbon source during water deficit, where their photosynthetic products were transferred and supplied to upper young leaves to promote stronger photosynthesis in young leaves to acquire resources for tree growth. This study highlights that the effect of leaf maturity should be considered in the future when investigating the effects of drought on woody plants, especially for continuously growing tree species. Therefore, our study not only demonstrates the existence of leaf‐age‐dependent responses to drought in poplar but also provides new insights into carbon allocation at the leaf level.
From Cognitive Agents to Cognitive Systems: Theoretical, Methodological, and Empirical Developments of van Gelder's (1998) “Dynamical Hypothesis”
Authors: Nguyen Tri D. , Magaldino Corey M. , Landfair Jayci T. , Amazeen Polemnia G. , Amazeen Eric L. 
Published: February 2024

AbstractOver two decades have passed since the publication of van Gelder's (1998) “dynamical hypothesis.” In that paper, van Gelder proposed that cognitive agents were not digital computers—per the representational computational approach—but dynamical systems. The evolution of the dynamical hypothesis was driven by parallel advances in three areas.Theoretically, a deeper understanding of genetics, biology, neuroscience, and cognitive science inspired questions about how systems within each domain dynamically interact and extend their effects across spatiotemporal scales.Methodologically, more sophisticated and domain‐general tools allowed researchers to discover, model, and quantify system dynamics, structure, and patterns across multiple scales to generate a more comprehensive system‐level understanding of behaviors.Empirically, we can analyze a system's behavior while preserving its natural dynamics, revealing evidence that the reductionist approach leads to an incomplete understanding of the components and the overall system. Researchers have traditionally reduced a complex system into its component processes and assumed that the parts can be recombined to explain the whole. These three advances fundamentally altered our understanding of a “cognitive agent:” How their behaviors are driven by long‐range coordination across multiple processes, how the interdependent and nested structure of interacting variables produces behaviors that are greater than the sum of its parts, and how environmental constraints shape adaptive yet stable behavioral patterns.
Voluntary blood donation preferences in China: A discrete choice experiment among experienced and inexperienced donors
Authors: Cao Chuqing , Wang Jing , Guo Tianyu , Hu Xinwen , Li Bo , Wu Caixia , Liu Zhong , Pan Stephen W. 
Published: February 2024

AbstractBackground and ObjectivesDue partly to an ageing population, China faces an increasingly dire blood shortage crisis requiring greater voluntary blood donations. A better understanding of blood donation preferences can inform blood donation policies and potentially increase donations. We used an online survey and discrete choice experiment to achieve our study objective: identify the most influential structural facilitators and barriers to voluntary blood donation in China.Materials and MethodsFirst, we identified six structural attributes (travel time, venue, donation volume, paid leave, scheduling and gifts) that were hypothesized to influence voluntary blood donation; attribute selection was based on a literature review and qualitative interviews. Second, a d‐efficient design with 36 choice sets and 9 blocks was developed. Participants were asked to complete four choice sets, and in each choice set, they were asked to choose from three options: two voluntary blood donation scenarios and a ‘Do not donate blood’ option. Study participants were recruited through an online survey platform company in China. Voluntary blood donation preferences and preferences by blood donation history were estimated with random‐parameter logit models and interaction terms.ResultsIn 2022, 1185 individuals enrolled in the study. Most participants had college education (92%). Generally, participants preferred longer paid leave, lower blood donation volumes and gifts after donation. Based on interaction analyses, experienced and inexperienced donors exhibited similar preferences.ConclusionCampaigns to increase voluntary blood donation rates in China should consider implementing paid leave after voluntary blood donation, lower blood donation volumes and small gifts conferred after donation.