bluuebunny/crossref_metadata_2025_split huggingface dataset:
Aprendizagem significativa em física na Educação de Jovens, Adultos e Idosos (EJAI) na Escola Estadual Professor José Carlos Quadros
Authors: Brito Layara Karyne , De Souza Rafaella Cristine , Ferreira Suelen Rocha Botão , Ferreira Welberth Santos 
Published: February 2024

Na educação de jovens, adultos e idosos (EJAI) a aprendizagem significativa desempenha um papel fundamental, pois esse grupo etário possui características e necessidades específicas. A EJAI busca uma educação que esteja relacionada diretamente aos seus interesses e objetivos de vida. Nessa linha, esta pesquisa tem como objetivo proporcionar um ambiente favorável a aprendizagem significativa a quatro (4) estudantes da primeira etapa do Ensino Médio (ensino da Cinemática) de uma escola pública localizada na região metropolitana da cidade de São Luís. Tendo o seguinte questionamento: como proporcionar um ambiente favorável a aprendizagem significativa a estudantes da EJAI? Trata-se de uma pesquisa qualitativa do tipo exploratória tendo como instrumento de constituição de dados uma avaliação diagnóstica e uma sequência didática. Assim, ao reconhecer as necessidades e interesses dos estudantes se promoveu uma conexão genuína com suas vidas, bem como houve um incentivo à participação ativa nos seus processos de aprendizagens.
Les spécificités des parasports mésestimées par le droit français
Authors: Ngo Mai-Anh , Pantaleon Nathalie , Richard Rémi , Joncheray Hélène , Beldame Yann 
Published: February 2024

Cet article a pour objectif d’analyser la réglementation du droit français en matière de handicap et en matière sportive, dans la perspective d’une application dans le domaine des parasports, défini comme la pratique d’activités sportives par des personnes en situation de handicap. L’étude se concentre en particulier sur la mise en œuvre des principes d’accessibilité et de compensation qui devaient permettre, comme le rappelle la loi du 11 février 2005, un égal accès aux équipements sportifs et aux pratiques pour les personnes en situation de handicap. Or, il s’avère que la mise en œuvre des obligations d’accessibilité, notamment aux équipements sportifs, reste problématique. Et que les droits à la compensation à travers l’obtention d’aide technique ou humaine restent limités en l’absence de considération explicite du domaine sportif. Ces difficultés constituent de véritables freins à la pratique sportive des personnes en situation de handicap. Pourtant, l’analyse du droit français démontre qu’il existe aussi des outils juridiques permettant un meilleur exercice des droits de l’accessibilité et de la compensation pour les personnes en situation de handicap. Au-delà d’une mobilisation différente du droit positif, des propositions sont faites pour améliorer la mise en œuvre des principes d’accessibilité et de compensation dans le domaine sportif, en particulier par le biais de la nomination de référents au sein des Maisons départementales des personnes handicapées.
Dans la tête du juge. Autour des travaux de Marion Vorms sur le raisonnement probatoire au tribunal
Authors: Vorms Marion 
Published: February 2024

Marion Vorms est maîtresse de conférences en philosophie à l’Université Paris 1 Panthéon-Sorbonne, chercheuse à l’Institut d’histoire et de philosophie des sciences et des techniques (UMR CNRS 8590) et membre de l’Institut universitaire de France. Docteure en philosophie des sciences, elle a d’abord étudié des questions de philosophie générale des sciences relatives à la représentation scientifique. Elle a par ailleurs étudié les problèmes épistémologiques posés par la dimension collective de la recherche scientifique (qui font l’objet de l’épistémologie sociale), avec une attention particulière au rôle du témoignage et de la confiance dans l’établissement des connaissances. Cette démarche l’a conduite à s’intéresser aux sciences cognitives, et plus précisément à la psychologie du raisonnement et à la cognition sociale. De 2015 à 2018, elle a bénéficié d’une bourse individuelle Marie Skłodowska-Curie, pour un projet de recherche interdisciplinaire au département de psychologie du Birkbeck College (Londres) sur le raisonnement et la prise de décision judiciaires, dans le cadre duquel elle s’interroge notamment sur la signification (juridique, et plus généralement épistémologique et psychologique) de la notion de doute raisonnable. Elle a ensuite approfondi son approche du droit français dans le Master 2 Justice et droit du procès (Université Paris 2). Le mémoire qu’elle a soutenu dans ce cadre, intitulé Le raisonnement probatoire des juges en France. Une approche épistémologique, est en accès libre à l’adresse suivante : https://docassas.u-paris2.fr/nuxeo/site/esupversions/988e7b01-d26b-4f0b-ab7e-92985b90c6e8
Les sciences sociales s’invitent au procès France Télécom
Authors: Beaudouin Valérie 
Published: February 2024

Au cours du procès France Télécom en première instance, qui s’est tenu en 2019, des chercheurs en sciences sociales sont venus témoigner à la barre, des travaux universitaires ont été cités. Devant le tribunal, des débats qui animent la recherche en sociologie se sont rejoués : les parties civiles et la défense ont chacun mobilisé les théories les mieux adaptées à leur stratégie. Tandis que les premiers insistaient sur le lien entre les conditions de travail et le suicide, les autres mettaient l’accent sur les effets de contagion et d’imitation (« effet Werther »). Par-delà ce conflit d’interprétation, les sciences sociales ont contribué lors du procès à faire entendre la dimension vindicative et collective de ces suicides et à déplacer l’attention vers la souffrance au travail, le suicide n’étant que le signe d’un malaise beaucoup plus global. Cette analyse qui s’appuie sur le live-tweet intégral du procès et sur les chroniques judiciaires montre comment dans ce procès le témoignage des experts invités par les parties civiles a contribué à renforcer l’accusation et le dossier d’instruction portant sur le harcèlement moral institutionnel.
Educational program on oral health “Healthy smile”: knowledge and role of legal responsibilities and educators
Authors: Montano-Silva Rosa María , Abraham-Millán Yoneisy , Peña-Méndez Aliana , Pérez-Cruz Yuliet , Navarro-González Ernestina , Ricardo-Díaz Luis Enrique 
Published: February 2024

Introduction: to achieve the health of infants and increase their quality of life, the health of legal guardians and educators is of particular importance; their beliefs and behaviors; and the ability, knowledge and will to acquire and provide the infant with healthy ways and styles of life. Objective: determine the effectiveness of the “Healthy Smile” Program in terms of knowledge about oral health of legal representatives and educators, as well as the role of educators of preschool infants. Methods: a quasi-experimental before-after research was carried out where the sample was 86 legal guardians and 9 preschool educators from the “La Demajagua-Atanagildo Cajigal” towns in the period 2021-2023. Results: the pre-university level of instruction predominated (68; 71,579 %) and a regular level of knowledge (73; 76,842 %) before the implementation of the program; the same being modified to good (77; 81,053 %) with a tendency to fair (18; 18,947 %). The educators significantly increased (8; 88,88 %) the reasons for preventing diseases related to the stomatognathic apparatus to maintain good oral hygiene; the results of the student T test showed statistically significant differences in knowledge of caries (X1=3,22; X2=3,80) and about children's oral health (X1=1,55; X2=3,44). Conclusions: the “Healthy Smile” program was effective in positively modifying the level of knowledge about oral health of legal representatives and educators, as well as in the role assumed by them with respect to the health of the infants in their care
O ENSINO DE DIREITOS HUMANOS E A FORMAÇÃO OMNILATERAL NO ENSINO MÉDIO INTEGRADO
Authors: Neves Juliane Laguna das , Scherer Renata Porscher 
Published: February 2024

O presente artigo propõe apresentar uma análise da literatura acadêmica brasileira entre os anos de 2019 a 2023 sobre o ensino dos Direitos Humanos e a formação omnilateral na educação profissional e tecnológica. Para este artigo foram analisadas 6 pesquisas, sendo duas teses e quatro dissertações. As pesquisas se destacaram por conterem em seu recorte o Ensino médio integrado e o ensino de Direitos Humanos objetivando a construção de uma sociedade mais digna, ambas destacam a importância do ensino em direitos Humanos para uma formação humana e cidadã. É possível evidenciar com as pesquisas selecionadas que o tema dos Direitos Humanos no ensino médio integrado está baseado na perspectiva de que são fundamentais para garantir que todos os indivíduos tenham acesso a uma educação de qualidade, inclusiva, equitativa e que promova o pleno desenvolvimento de suas capacidades possibilitando aos sujeitos que se posicionem questionando os processos de produção e de distribuição de riqueza, edificando, assim, uma sociedade mais justa, em que todos tenham assegurados o seu direito a uma subsistência digna.
Fumarate Hydratase–Deficient Renal Cell Carcinoma With Predominant Tubulocystic Features Mimics Tubulocystic Renal Cell Carcinoma
Authors: Yang Xiaoqun , Liu Yang , Wang Huafeng , Xu Yunze , Zhang Huizhi , Zhao Ming , Luo Xiaoqing , Jin Hongtao , Xiong Ji , Tao Lili , Xu Jiankun , Zhou Luting , Li Xiangyun , Xu Haimin , Dong Lei , Wang Chaofu 
Published: February 2024

Context.—
Fumarate hydratase (FH)–deficient renal cell carcinoma (RCC) rarely exhibits a predominant tubulocystic architecture with few other components. RCC with pure tubules and cysts lined by eosinophilic tumor cells with prominent nucleoli would raise the diagnosis of tubulocystic RCC. It is important to differentiate the 2 entities because they lead to different outcomes.

Objective.—
To address this concern, a multicenter study was implemented to explore useful clinicopathologic features in differentiation between tubulocystic FH-deficient RCC and tubulocystic RCC.

Design.—
Clinical factors included age, sex, tumor size, and outcome. Morphologic factors included cell morphology, presence or absence of a nontubulocystic component, and stromal findings. Immunohistochemistry, fluorescence in situ hybridization, and next-generation sequencing were performed to explore the protein expression and molecular profiles of the 2 entities.

Results.—
We evaluated 6 patients with tubulocystic RCC and 10 patients with tubulocystic FH-deficient RCC. Tubulocystic RCC exhibited a small size (&lt;4.0 cm, pT1a), low Ki-67 index (&lt;5%), retained FH, and negative 2SC expression. Tubulocystic FH-deficient RCC had a relatively large size and a high Ki-67 index. Perinucleolar haloes, loss of FH, and 2SC positivity were always observed. Pure tubulocystic architecture was not observed in FH-deficient RCC, because focal nontubulocystic components can always be seen.

Conclusions.—
We emphasized multiple sectioning to identify a nontubulocystic architecture to exclude tubulocystic RCC. Moreover, tumor size, FH/2SC staining, and the Ki-67 index can differentiate tubulocystic FH-deficient RCC from tubulocystic RCC. The diagnosis of tubulocystic RCC was not recommended in renal mass biopsy because of the limited tissues sampled.
Performance-Based Assessment for Certification: Insights from edTPA Implementation
Authors: Lachuk Amy Johnson , Koellner Karen 
Published: February 2024

In this essay, two teacher educators share the tensions they experienced in implementing program-wide interventions in response to the edTPA adoption. In particular, we share how we experienced tensions between 1) telling teacher candidates how to teach and supporting their growth through self-directed reflection, 2) carrying ourselves with confidence in the face of uncertainty about the newly state-mandated edTPA examination, 3) valuing teacher candidates' prior experiences with teaching and learning, and helping them reconstruct their experiences in a way that would support them with the edTPA examination. We share the insights we gained about edTPA implementation from experiencing these tensions
A Nerve Block Team in the Emergency Department
Authors: Perice Leland , Hoffman Taryn , Hsu Joann , Stoll Christopher , Lin Judy , Motov Sergey , Likourezos Antonios , Haines Lawrence , Dickman Eitan , Naraghi Leily 
Published: February 2024

Objectives To improve pain management in the emergency department (ED), emergency physicians are performing an increasing number of ultrasound-guided regional anesthesia procedures (nerve blocks). We aimed to examine the effect of a dedicated emergency department (ED) nerve block team (NBT) on the number and types of ultrasound-guided nerve blocks administered in the ED. Methods We performed a retrospective chart review comparing the nine-month period before and after the creation of a dedicated NBT. This was performed at a tertiary care urban hospital that is a level 1 trauma center. We assessed and compared the number and types of nerve blocks performed, level of learners who performed nerve blocks, and time of ED arrival to disposition, before and after implementation of the NBT. Results The utilization of nerve blocks rose from 79 prior to the establishment of the NBT to 108 following its creation, representing a 36.7% increase. The average duration of stay in the emergency department decreased by 51 minutes, though this change did not demonstrate statistical significance (P=0.1237). There was an increased variety in the types of nerve blocks performed. Conclusion The introduction of a NBT led to a rise in both the quantity and diversity of nerve blocks conducted in the ED.
HUBUNGAN PENGETAHUAN, SIKAP DAN PERILAKU CALON PENGANTIN TERHADAP KEJADIAN ANEMIA PADA CALON PENGANTIN DI WILAYAH KERJA UPTD PUSKESMAS CIPAYUNG TAHUN 2023
Authors: Candrawati Elly , Hidayani Hidayani , Sari Agustina 
Published: February 2024

Pendahuluan : Wanita mempunyai risiko terkena anemia paling tinggi terutama pada remaja putri. Pengetahuan merupakan salah satu komponen faktor predisposisi yang penting untuk perilaku kesehatan. Apabila seorang calon ibu memiliki pengetahuan yang lebih tentang risiko tinggi kehamilan yang akan datang maka kemungkinan besar calon ibu akan berpikir untuk mencegah, menghindari atau mengatasi masalah risiko kehamilan tersebut, dan calon ibu memiliki kesadaran untuk memeriksakan kesehatannya. Angka kejadian anemia pada calon pengantin di wilayah kerja UPTD Puskesmas Cipayung cukup tinggi. Tujuan : Penelitian ini bertujuan untuk mengetahui hubungan pengetahuan, sikap dan perilaku calon pengantin terhadap kejadian anemia di wilayah kerja UPTD Puskesmas Cipayung Tahun 2023. Metode : Menggunakan desain cross sectional dan bersifat analitik kuantitatif Hasil : Dari 35 responden, terdapat 34,3% calon pengantin wanita mengalami anemia. Responden dengan pengetahuan baik sebanyak 60 %, sikap yang baik 57,1 %, dan 62,9 % memiliki perilaku yang positif. Hasil uji statistic menggunakan chi square antara lain terdapat hubungan antara pengetahuan (p=0,02), sikap (p=0,04) terhadap kejadian anemia calon pengantin sedangkan untuk perilaku calon pengantin tidak ada hubungan yang signifikan dengan kejadian anemia calon pengantin (p=0,256). Penelitian ini mampu menjadi dasar untuk melaksanakan program edukasi terhadap rematri dan calon pengantin tentang pencegahan anemia untuk calon pengantin.
Percutaneous Biliary Interventions for Malignant Biliary Obstruction in Low and Middle-Income Countries: Experiences of Northwestern Nigeria
Authors: Ismail Anas , Umar Ahmad Bashir , Lawal Yusuf , Bello Usman M. , Inuwa Yusuf , Ahmad Nafiu , Tabari Abdulkadir Musa , Swanson Allen 
Published: February 2024

Introduction: Malignant causes of biliary obstruction are common in low and middle-income countries (LMICs) and patients usually present late with unresectable masses. The options for endoscopic and surgical management are scarce in many LMICs. In settings with access to ultrasound and fluoroscopy, percutaneous biliary drainage (PBD) is a promising and minimally invasive option for relieving obstruction and improving the quality of life of these patients.
Method: We present a case series of six patients in northwestern Nigeria with cholestatic jaundice caused by malignant biliary obstruction successfully treated by PBD.
Results: In five cases, imaging revealed a locally invasive pancreatic head mass causing obstruction. One of the patients had obstruction from biopsy-proven cholangiocarcinoma. Three patients had internal biliary drainage past the obstruction and three patients had only external biliary drainage due to the severity of the obstructions. One patient with internal drainage went on to cholangioplasty and deployment of the balloon-expandable stent over the stenotic segment. All procedures were uncomplicated and patients had a gradual clearance of jaundice and resolution of pruritus. Two of the elderly patients died within six months of the procedure (one from hepatic encephalopathy and the other from stroke). The remaining four survived but were lost to follow-up by 10 months.
Conclusions: PBD is a feasible and beneficial option for decompressing malignant biliary obstruction in LMICs.
The relationship between cancer associated fibroblasts biomarkers and prognosis of breast cancer: a systematic review and meta-analysis
Authors: Cui Meimei , Dong Hao , Duan Wanli , Wang Xuejie , Liu Yongping , Shi Lihong , Zhang Baogang 
Published: February 2024

Background
To elucidate the relationship between cancer-associated fibroblast (CAFs) biomarkers and the prognosis of breast cancer patients for individualized CAFs-targeting treatment.

Methodology
PubMed, Web of Science, Cochrane, and Embase databases were searched for CAFs-related studies of breast cancer patients from their inception to September, 2023. Meta-analysis was performed using R 4.2.2 software. Sensitivity analyses were performed to explore the sources of heterogeneity. Funnel plot and Egger’s test were used to assess the publication bias.

Results
Twenty-seven studies including 6,830 patients were selected. Univariate analysis showed that high expression of platelet-derived growth factor receptor-β (PDGFR-β) (P = 0.0055), tissue inhibitor of metalloproteinase-2 (TIMP-2) (P < 0.0001), matrix metalloproteinase (MMP) 9 (P < 0.0001), MMP 11 (P < 0.0001) and MMP 13 (P = 0.0009) in CAFs were correlated with reduced recurrence-free survival (RFS)/disease-free survival (DFS)/metastasis-free survival (MFS)/event-free survival (EFS) respectively. Multivariate analysis showed that high expression of α-smooth muscle actin (α-SMA) (P = 0.0002), podoplanin (PDPN) (P = 0.0008), and PDGFR-β (P = 0.0470) in CAFs was associated with reduced RFS/DFS/MFS/EFS respectively. Furthermore, PDPN and PDGFR-β expression in CAFs of poorly differentiated breast cancer patients were higher than that of patients with relatively better differentiated breast cancer. In addition, there is a positive correlation between the expression of PDPN and human epidermal growth factor receptor-2 (HER-2).

Conclusions
The high expression of α-SMA, PDPN, PDGFR-β in CAFs leads to worse clinical outcomes in breast cancer, indicating their roles as prognostic biomarkers and potential therapeutic targets.
Wolbachia and reproductive conflict in Exorista sorbillans
Authors: Puttaraju H.P. , Prakash B.M. 
Published: November 2005

AbstractMany arthropods harbour endosymbiotic bacteria of the genus Wolbachia. These endosymbionts are transmitted vertically from one generation to the next and are obligatory in several Dipterans that have been studied to date. These bacteria induce an array of reproductive isolation mechanisms that are implicated in pest management to evolutionary biology of respective hosts. The uzifly, Exorista sorbillans, a tachinid endoparasitoid of the silkworm, Bombyx mori L. (Lepidoptera: Bombycidae), causes enormous losses to the silk industry; now it is known that it harbours Wolbachia endobacteria. The elimination of Wolbachia by antibiotics interrupts embryogenesis and causes various reproductive conflicts such as (1) a reduction of fecundity of uninfected female, (2) cytoplasmic incompatibility in the uninfected females crossed with infected males, (3) genomic incompatibility in crosses between males and females from uninfected population, and (4) sex‐ratio distortion in uninfected females irrespective of the presence of Wolbachia in males. These results suggest that the relationship of Wolbachia with its uzifly host is one of mutual symbiosis as it controls the reproductive physiology of its host. Arch. Insect Biochem. Physiol. 60:230–235, 2005. © 2005 Wiley‐Liss, Inc.
Developmental interaction between suboptimal instars of Spodoptera littoralis (Lepidoptera:Noctuidae) and its parasitoid Microplitis rufiventris (Hymenoptera:Braconidae)
Authors: Hegazi Esmat , Khafagi Wedad 
Published: November 2005

AbstractRelative effects of parasitism by Microplitis rufiventris on the development of the third instar Spodoptera littoralis (preferable, optimal host) with the development of penultimate (5th) and last (6th) instars (suboptimal hosts) were investigated. Newly molted 6th instar hosts were more acceptable for parasitization by the wasp female than older hosts. In singly parasitized 3rd instar hosts, 82.0 ± 3.9% of the parasitoid eggs developed to full‐grown instar wasp larvae. However, parasitoid eggs deposited singly in 73.9 ± 3.3% of 5th and 100% of 6th instar hosts failed to develop. Superparasitization in the 3rd instar hosts reduced the production of pseudoparasitized larvae and, conversely, all parasitized hosts yielded viable parasitoid offspring. In suboptimal hosts, the development interaction between the parasitoid and its host larvae was highly influenced by the age of hosts at parasitism, load of deposited eggs, and other parasitoid factors. The latter factors, e.g., mainly calyx fluid particles, might be involved in establishing parasitoid eggs in the suboptimal hosts. In the last two host instars, superparasitization significantly increased the number of parasitoid larvae successfully reaching their final instar. Variation in host quality, e.g., physiological status, might be attributed, in part, to the partial breakdown of the solitary habit observed in the earlier instars. More parasitoid eggs developed to mature parasitoid larvae in hosts superparasitized as 6th instar than parasitoid eggs laid in 5th instar hosts. Superparasitization significantly lengthened the developmental period of 5th and 6th host instars and inhibited their development to the pupal stage. Studying parasitoid development in suboptimal instars of its habitual host provided physiological insight, as shown here. The results may have implication for biological control and in vitro mass rearing programs with solitary parasitoids. Arch. Insect Biochem. Physiol. 60:172–184, 2005. © 2005 Wiley‐Liss, Inc.
Are insect immune suppressors driving cellular uptake reactions?
Authors: Schmidt Otto , Glatz Richard V. , Asgari Sassan , Roberts Harry L.S. 
Published: November 2005

AbstractMany insect parasitoids that deposit their eggs inside immature stages of other insect species inactivate the cellular host defence to protect the growing embryo from encapsulation. Suppression of encapsulation by polydnavirus‐encoded immune‐suppressors correlates with specific alterations in hemocytes, mainly cytoskeletal rearrangements and actin‐cytoskeleton breakdown. We have previously shown that the Cotesia rubecula polydnavirus gene product CrV1 causes immune suppression when injected into the host hemocoel. CrV1 is taken up by hemocytes although no receptors have been found to bind the protein. Instead CrV1 uptake depends on dimer formation, which is required for interacting with lipophorin, suggesting a CrV1‐lipophorin complex internalisation by hemocytes. Since treatment of hemocytes with oligomeric lectins and cytochalasin D can mimic the effects of CrV1, we propose that some dimeric and oligomeric adhesion molecules are able to cross‐link receptors on the cell surface and depolymerise actin by leverage‐mediated clearance reactions in the hemolymph. Arch. Insect Biochem. Physiol. 60:153–158, 2005. © 2005 Wiley‐Liss, Inc.