bluuebunny/crossref_metadata_2025_split huggingface dataset:
Existence of long-range magnetic order in Heisenberg spin nanoribbons with edge modification
Authors: Ma Da-cheng , Cui Ling-yi , Sun Chu-xiao , Chi Xiao-dan , XianYu Zheng-Nan , Du An 
Published: April 2024

Abstract
Long-range magnetic order appears on a side decorated Heisenberg spin nanoribbon at nonzero temperature, although no spontaneous magnetization exists in a one- or two-dimensional isotropic Heisenberg model at any nonzero temperature according to the Mermin–Wagner theorem. By use of the spin Green’s function method, we calculated the magnetizations of Heisenberg nanoribbons decorated by side spins with single-ion anisotropy and found that the system exhibits a nonzero transition temperature, whether the decorated edge spins of the system link together or separate from each other. When the width of the nanoribbon achieves infinite limit, the transition temperatures of the system tend to the same finite constant eventually whether one edge or both edges are decorated by side spins in the nanoribbon. The results reveal that the magnetism of a low-dimensional spin system is different from that of a three-dimensional spin system. When the single-ion anisotropy of edge spins in a Heisenberg spin nanoribbon can be modulated by an electric field experimentally, various useful long-range magnetic orders of the system can be obtained. This work can provide a detailed theoretical basis for designing and fabricating next-generation low-dimensional magnetic random-access memory.
28 nm front-end channels for the readout of pixel sensors in future high-rate applications
Authors: Gaioni L. , Galliani A. , Ratti L. , Re V. , Traversi G. 
Published: April 2024

Abstract
This work is concerned with the design and the characterization of front-end channels, developed in a 28 nm CMOS technology, conceived for the readout of pixel sensors in future, high-rate applications at the next generation facilities.
Two front-end architectures are discussed. In the first one, an in-pixel flash ADC is exploited for the digitization of the signal, whereas the second one features a Time-over-Threshold (ToT) approach. A prototype including the ADC-based front-end has been submitted and the characterization of the chip is discussed in the paper. Simulation results relevant to the ToT-based architecture are reported.
Performance of H2GCROC3, the readout ASIC of SiPMs for the back hadronic sections of the CMS High Granularity Calorimeter
Authors: González-Martínez J.D. ,   the CMS collaboration
Published: April 2024

Abstract
H2GCROC is a 130 nm CMOS ASIC designed to read out the SiPMs coupled to the scintillating tiles of the back hadronic sections of CMS HGCAL. Each of its 72 channels comprises a current conveyor, a high-gain preamplifier, a shaper, an ADC for energy measurement, and two discriminators linked to TDCs for capturing time-of-arrival and time-over-threshold information, respectively. This work presents the ASIC architecture and its characterization in the laboratory and test beam environments. The results demonstrate its adaptability in calibration, proving its capability to measure the SiPM single-photon spectrum and MIP's energy with high resolution under the expected radiation conditions during the entire operation of HGCAL.
Characterization of the FOOT neutron detectors for nuclear fragmentation measurements at the n_TOF facility
Authors: Zarrella R. , Manna A. , Amaducci S. , Bacak M. , Casanovas A. , Colombi S. , D'Orazio C. , García-Infantes F. , Malekinezhad N. , Marafini M. , Massimi C. , Mengoni A. , Musumarra A. , Patronis N. , Pavón-Rodríguez J.A. , Pellegriti M.G. , Spighi R. , Stamati E. , Villa M. ,   the FOOT and n_TOF collaborations
Published: April 2024

Abstract
FOOT (FragmentatiOn Of Target) is an applied nuclear physics experiment with the aim of performing high precision cross section measurements for fragmentation reactions of interest in hadrontherapy and radiation protection in space. The physics program of the experiment foresees a set of measurements with light ion beams, such as C and O, in the energy range of 100–800 MeV/u interacting with tissue-like and shielding material targets. The setup was initially conceived for the detection of charged fragments and, in 2021, the Collaboration started the study of possible solutions for neutron detection. Two detection systems have been proposed: one based on BC-501A liquid scintillators with neutron/γ discrimination capabilities and a system based on BGO crystals operated in phoswich mode. In 2022, a dedicated data acquisition campaign was carried out at the n_TOF facility at CERN to evaluate the capabilities of the two systems. First, the neutron/γ discrimination efficiency of the BC-501A system was studied using radioactive sources. Then, the two systems were placed in the n_TOF experimental area to study their neutron detection efficiency under a well characterized neutron beam. In this work, the first preliminary results concerning the characterization of the two possible neutron detectors of FOOT are presented.
Signal classification algorithms for the MRPC with DRS4 readout
Authors: Malakhov A. , Daribayeva A. , Dmitriev A. 
Published: April 2024

Abstract
The readout electronics of the Multigap Resistive Plate
Chambers (MRPC) of the NA61/SHINE experiment at CERN are based on
the Domino Ring Sampler v.4 (DRS4) chips. Due to the analyzing
complexity of the waveforms produced by the MRPC with DRS4 readout,
one needs to develop a reliable algorithm in order to distinguish
signal from noise. Two methods are investigated, using the beam test
data on MRPC with DRS4 readout held at “PAKHRA” accelerator in LPI
RAS, Troitsk. Their results are estimated within the comparative
approach, as well as the possibility of their implementation for
different purposes.
Recent progress in 3D printing of Bi2Te3-based thermoelectric materials and devices
Authors: Yang S E , Han H , Son J S 
Published: April 2024

Abstract
With growing concerns about the depletion of fossil fuels and climate change, there is an urgent global demand for the development of sustainable and renewable energy sources. The thermoelectric technology, which converts waste heat into electricity, presents a unique opportunity to ensure a sustainable electric supply and enhance energy efficiency without incurring additional costs. Recently, the utilization of three-dimensional (3D) printing technology for fabricating thermoelectric materials has attracted tremendous interest because of the simplicity of design of power generators and the potential for economical manufacturing. This study focuses on research related to Bi2Te3 thermoelectric materials produced using 3D printing, and it highlights the fundamental principles, advantages, challenges, and recent remarkable advancements associated with this manufacturing approach. Furthermore, we explored various device applications, including shape-conformable wearable, and micro devices with printed thermoelectric materials. Finally, we discuss the promising research directions and prospects for industrialization in 3D-printed thermoelectric materials.
Silicon flow stop frame for encapsulation of CMOS microsensor chips by wet anisotropic etching in KOH
Authors: Dobroliubov A , Kakati A , Stokke B T , Häfliger P , Johannessen E A 
Published: April 2024

Abstract
Bulk micromachining in silicon is governed by the etching process where anisotropic (wet) etching in KOH can yield complex structures beyond that achievable with isotropic (dry) etching techniques. One example is the miniaturised frame reported herein with an area of 2.9 to 7.5 mm2, walls that are 1/10 mm thick, a height of 525 μm equipped with sloping walls that takes advantage of the 54.7° angle of the (111) planes to the horizontal (100) top surface of the wafer. Convex corners liable to damage are protected by sacrificial bridge structures which are etched thin to a point where the frame can be easily removed from the bulk substrate material. Frames made from isotropic (dry) etching processes have been made for comparison. Although the frame structure has different applications in microfabrication, the intended use is a flow stop barrier preventing liquid resins from entering the active area of a CMOS chemical sensor chip during encapsulation for use in aqueous or gaseous media. Beyond this specific proof-of-concept, the strategy is expected to be of general interest for all who treasures KOH etching and wants to explore new avenues based on this process.
Influence of incomplete death information on cumulative risk estimates in US claims data
Authors: Barberio Julie , Naimi Ashley I , Patzer Rachel E , Kim Christopher , Hernandez Rohini K , Brookhart M Alan , Gilbertson David , Bradbury Brian D , Lash Timothy L 
Published: April 2024

Abstract
Administrative claims databases often do not capture date or fact of death, so studies using these data may inappropriately treat death as a censoring event—equivalent to other withdrawal reasons—rather than a competing event. We examined 1-, 3-, and 5-year inverse-probability-of-treatment weighted cumulative risks of a composite cardiovascular outcome among 34 527 initiators of telmisartan (exposure) and ramipril (referent), who were aged ≥55 years, in Optum (United States) claims data from 2003 to 2020. Differences in cumulative risks of the cardiovascular endpoint due to censoring of death (cause-specific), as compared with treating death as a competing event (subdistribution), increased with greater follow-up time and older age, where event and mortality risks were higher. Among ramipril users, 5-year cause-specific and subdistribution cumulative risk estimates per 100, respectively, were 16.4 (95% CI, 15.3-17.5) and 16.2 (95% CI, 15.1-17.3) among ages 55-64 (difference = 0.2) and were 43.2 (95% CI, 41.3-45.2) and 39.7 (95% CI, 37.9-41.4) among ages ≥75 (difference = 3.6). Plasmode simulation results demonstrated the differences in cause-specific versus subdistribution cumulative risks to increase with increasing mortality rate. We suggest researchers consider the cohort’s baseline mortality risk when deciding whether real-world data with incomplete death information can be used without concern.
This article is part of a Special Collection on Pharmacoepidemiology.
Meta-analysis of the quantitative effectiveness of risk management measures (RMM) in the workplace
Authors: Goede Henk , Ge Calvin , Fransman Wouter 
Published: April 2024

Abstract

Background and objectives
This paper describes an evaluation and analysis of an updated version of ECEL v3.0—an integrated risk management measure (RMM) library developed as part of a CEFIC LRI initiative. The occupational module contains extensive data on the quantitative effectiveness of RMMs to control inhalation and dermal exposure in the workplace. The objective was to investigate the effectiveness and variability in effectiveness of RMM and to explore the difference between optimal and non-optimal RMM applications in the workplace.

Methods
A new database structure and interface were developed and the content of the database was updated with a systematic literature review and integration with other databases (totalling 3373 records from 548 studies). To analyse the data, Bayesian linear mixed models were constructed with the study as a random effect and various study characteristics and RMM categories as fixed effects individually in separate models. A multivariate mixed model was used on a stratified dataset to test (amongst others) the conditions of RMM use.

Results
Analyses of the data indicated effectiveness values for each RMM category (for example ~87% for technical emission controls compared with ~60% for technical dispersion controls). Substantial variability in effectiveness was observed within and between different types of RMM. Seven study characteristics (covariables) were included in the analyses, which indicated a pronounced difference in as-built (optimal/experimental) and as-used (workplace) conditions of RMM use (93.3% and 74.6%, respectively).

Conclusions
This library provides a reliable evidence base to derive base estimates of RMM effectiveness—beneficial for both registrant and downstream users. It stresses the importance of optimal use of RMMs in the workplace (technical design/functioning, use, and maintenance). Various challenges are foreseen to further update ECEL to improve guidance, for deriving improved estimates and ensure user-friendliness of the library.
Catechol-O-methyltransferase and monoamine oxidase B inhibitory activities of Australian bee pollen
Authors: Watanabe Chie , Yanagihara Aoi , Miyata Ryo , Mitsui Taichi , Honda Chihiro , Fujinami Daisuke , Kumazawa Shigenori 
Published: April 2024

Abstract
Bee pollen is an apicultural product collected by honeybees from flower stamens and used as a functional food worldwide. In the present study, we aim to elucidate the functions of Australian bee pollen. Australian bee pollen extracts and their main components were tested for catechol-O-methyltransferase (COMT) and monoamine oxidase B (MAOB) inhibitory activities. These enzymes are key neurotransmitters involved in Parkinson's disease and depression. Myricetin (5), tricetin (6), and luteolin (7) exhibited high COMT inhibitory activities (half maximal inhibitory concentration [IC50] = 23.3, 13.8, and 47.4 µM, respectively). In contrast, 5, 7, and annulatin (8) exhibited MAOB inhibitory activities (IC50 = 89.7, 32.8, and 153 µM, respectively). Quantitative analysis via high-performance liquid chromatography revealed that 5 was abundant in Australian bee pollen extracts. Our findings suggest that 5 contributes to the COMT and MAOB inhibitory activities of Australian bee pollen.
Small-scale land-use change effects on breeding success in a desert-living social bird
Authors: Oswald Krista N , Berger-Tal Oded , Roll Uri 
Published: April 2024

Abstract
Human villages in deserts can provide resources in an otherwise stark environment, potentially buffering against extreme environmental conditions. It is thus expected that breeding within these villages would result in higher fitness. However, choosing to raise offspring in these resource-rich environments may have unintended negative consequences. Here, we studied the breeding success of a cooperative breeding bird nesting in habitats with different levels of human disturbance—the Arabian babbler (Argya squamiceps), in the Negev desert of Israel. We recorded 42 breeding attempts from 15 groups between March and July 2022. We examined overall breeding success, brood size, and causes of nest failure. When nestlings were 6 days old, we also calculated daily change in body mass and adult provisioning rate. We found that despite higher resource abundance in villages, proximity to villages did not affect provisioning rate, and nestlings gained less mass at higher temperatures for all nests. Currently, there is no evidence that human villages are providing oases of resources for nesting babblers. Further, various conservation interventions (e.g., encouraging residents to keep cats indoors) could improve babblers’ overall fitness. Ultimately, we highlight how, for some desert specialists, additional resources provided by humans may not do enough to counter potential negative effects.
ConvNeXt-MHC: improving MHC–peptide affinity prediction by structure-derived degenerate coding and the ConvNeXt model
Authors: Zhang Le , Song Wenkai , Zhu Tinghao , Liu Yang , Chen Wei , Cao Yang 
Published: April 2024

Abstract
Peptide binding to major histocompatibility complex (MHC) proteins plays a critical role in T-cell recognition and the specificity of the immune response. Experimental validation such peptides is extremely resource-intensive. As a result, accurate computational prediction of binding peptides is highly important, particularly in the context of cancer immunotherapy applications, such as the identification of neoantigens. In recent years, there is a significant need to continually improve the existing prediction methods to meet the demands of this field. We developed ConvNeXt-MHC, a method for predicting MHC-I-peptide binding affinity. It introduces a degenerate encoding approach to enhance well-established panspecific methods and integrates transfer learning and semi-supervised learning methods into the cutting-edge deep learning framework ConvNeXt. Comprehensive benchmark results demonstrate that ConvNeXt-MHC outperforms state-of-the-art methods in terms of accuracy. We expect that ConvNeXt-MHC will help us foster new discoveries in the field of immunoinformatics in the distant future. We constructed a user-friendly website at http://www.combio-lezhang.online/predict/, where users can access our data and application.
The IDSM mass spectrometry extension: searching mass spectra using SPARQL
Authors: Galgonek Jakub , Vondrášek Jiří 
Published: April 2024

Abstract

Summary
The Integrated Database of Small Molecules (IDSM) integrates data from small-molecule datasets, making them accessible through the SPARQL query language. Its unique feature is the ability to search for compounds through SPARQL based on their molecular structure. We extended IDSM to enable mass spectra databases to be integrated and searched for based on mass spectrum similarity. As sources of mass spectra, we employed the MassBank of North America database and the In Silico Spectral Database of natural products.

Availability and implementation
The extension is an integral part of IDSM, which is available at https://idsm.elixir-czech.cz. The manual and usage examples are available at https://idsm.elixir-czech.cz/docs/ms. The source codes of all IDSM parts are available under open-source licences at https://github.com/idsm-src.
Improvement in Health-Related Quality of Life Following Antibiotic Treatment in Nontuberculous Mycobacterial Pulmonary Disease: Initial Analysis of the NTM-KOREA Cohort
Authors: Kwak Nakwon , Henkle Emily , Hwang Hyeontaek , Jeon Doosoo , Jhun Byung Woo , Jo Kyung-Wook , Kang Young Ae , Kim Hyung-Jun , Kim Joong-Yub , Kim Young Ran , Kwon Yong-Soo , Lee Jae Ho , Mok Jeongha , Park Youngmok , Shim Tae Sun , Sohn Hojoon , Whang Jake , Yim Jae-Joon 
Published: April 2024

Abstract

Background
Improving health-related quality of life (HRQOL) has emerged as a priority in the management of nontuberculous mycobacterial pulmonary disease (NTM-PD). We aimed to evaluate HRQOL and its changes after 6 months’ treatment in patients with NTM-PD.

Methods
The NTM-KOREA is a nationwide prospective cohort enrolling patients initiating treatment for NTM-PD in 8 institutions across South Korea. We conducted the Quality of Life–Bronchiectasis (QOL-B) at 6-month intervals and evaluated baseline scores (higher scores indicate better quality of life) and changes after 6 months’ treatment. Multivariate logistic regression was performed to identify factors associated with improvement in the QOL-B physical functioning and respiratory symptoms domains.

Results
Between February 2022 and August 2023, 411 patients were included in the analysis. Baseline scores (95% confidence interval [CI]) for physical functioning and respiratory symptoms were 66.7 (46.7–86.7) and 81.5 (70.4–92.6), respectively. Among 228 patients who completed the QOL-B after 6 months’ treatment, improvements in physical functioning and respiratory symptoms were observed in 61 (26.8%) and 71 (31.1%) patients, respectively. A lower score (adjusted odds ratio; 95% CI) for physical functioning (0.93; 0.91–0.96) and respiratory symptoms (0.92; 0.89–0.95) at treatment initiation was associated with a greater likelihood of physical functioning and respiratory symptom improvement, respectively; achieving culture conversion was not associated with improvement in physical functioning (0.62; 0.28–1.39) or respiratory symptoms (1.30; 0.62–2.74).

Conclusions
After 6 months of antibiotic treatment for NTM-PD, HRQOL improved in almost one-third, especially in patients with severe initial symptoms, regardless of culture conversion.

Clinical Trials Registration
ClinicalTrials.gov identifier: NCT03934034.
Proning the extracorporeal membrane oxygenation plus Impella: a case report
Authors: de Jongh Marjolein C , Bax Matthijs , Ayan Khalil , Akin Sakir 
Published: April 2024

Abstract

Background
The prone position is recommended as supportive therapy in patients with moderate-to-severe acute respiratory distress syndrome (ARDS). However, little is known about prone position ventilation in patients with cardiogenic shock supported by extracorporeal membrane oxygenation (ECMO) plus Impella (ECPELLA) developing ARDS.

Case summary
A 66-year-old man with severe left ventricular dysfunction was admitted to a non-academic ECMO centre for a high-risk coronary artery bypass grafting. He developed post-cardiotomy shock needing ECMO support. To improve left ventricular unloading, an Impella was inserted 2 days later. One day later, he developed ARDS and needed prone position ventilation with ECPELLA in situ. After 4 weeks, he was discharged from the intensive care unit.

Discussion
Previous studies demonstrated that prone positioning could help avoid an additional venous cannula in veno-arterial ECMO patients, which is associated with mechanical complications. In this case, there was a promising role for unloading the left ventricle with Impella during veno-arterial ECMO and, for proning, the patient with cardiogenic shock developing ARDS during ECMO support without the need for an extra venous cannula.
The effectiveness of physical activity interventions in improving higher education students’ mental health: A systematic review
Authors: Donnelly Samantha , Penny Kay , Kynn Mary 
Published: April 2024

AbstractTraditional interventions aiming to improve students’ mental health and quality of life include meditation or canine therapy. The development of physical activity-related interventions has increased over the past decade. We aimed to review all studies using physical activity for improving the mental health and quality of life in higher education students whilst describing the interventions, measurements and effectiveness. A systematic search of six electronic databases including: ProQuest, MEDLINE, Embase, CINAHL, SPORTDiscus and CENTRAL, was conducted following PRISMA guidelines. Randomized or non-randomized controlled trial physical activity-related interventions involving higher education students aiming to improve their mental health and quality of life were included. Searches yielded 58 articles with interventions involving martial arts, sport, mind–body exercises and anaerobic exercises. Psychological measures varied across studies including the State Trait Anxiety Inventory, Beck Depression Inventory and the Perceived Stress Scale. Over half of the studies included in this review (n = 36) were effective in improving students’ mental health or quality of life. Findings from our review suggest that interventions aiming to be effective in improving students’ mental health quality of life should aim to deliver moderate-vigorous intensity exercises such as dance or Pilates. This systematic review was based on a published protocol in PROSPERO (registration number: CRD42022325975).
Robots and reshoring: a comparative study of automation, trade, and employment in Europe
Authors: Chen Chinchih , Frey Carl Benedikt 
Published: April 2024

Abstract
This paper constitutes a comparative assessment of the impact of robots on local labor markets across eight European countries. Doing so, we find that robots generally reduce employment in the manufacturing sector, while their impacts on total employment are more ambiguous. Though local markets experienced significant employment losses in Italy, Norway, and the United Kingdom, we find no statistically significant impact of robots on employment in Germany, Sweden, Denmark, Finland, and Spain. Job losses were seemingly offset by employment gains in other sectors of the economy. We explore two mechanisms that might explain these patterns: differences in investment in complementary job-creating technologies and robot-induced reshoring. Our analysis provides some support for both mechanisms in elucidating the differential impacts of robots on jobs across space.