bluuebunny/crossref_metadata_2025_split huggingface dataset:
The morphological and syntactic functions of Dagbani nominal suffixes
Authors: Hudu Fusheini , Iddrisu Abdallah 
Published: April 2024

Abstract
One of the defining morphological properties of nouns and adjectives of Dagbani (a Gur/Mabia language of northern Ghana) and related languages is the presence of suffixes that mark number (singular or plural) as well as serve as the basis for noun classification. The typical regular noun or adjective (e.g. bi-a ‘a child’) consists of a bound root (bi-) providing the lexical meaning, and a suffix (-a) which indicates the singular number of the noun. In plural form, the suffix is replaced by a different one that marks plurality: (bi-hi). In this paper, we show that while this broad description is generally accepted, it is much weaker than assumed in previous studies, with many inconsistencies. As our main goal, we offer a much broader analysis of the morphological and syntactic functions of the nominal suffixes. We show that these suffixes are primarily there to project lexical words as nouns and adjectives and should be referred to as nominal suffixes used to inflect inherent nouns and derive nouns and adjectives from verbs. The nominal suffixes are also crucial to distinguishing between different compound nouns and noun phrases. The paper is largely descriptive, with no specific theoretical approach assumed.
Indonesian Sundanese Local Wisdom as An Ethical Reference in Digital Media
Authors: Sjafirah Nuryah Asri , Indriani Sri Seti , Yanto Andri , Sjuchro Dian Wardiana , Viannisa Nadhifa 
Published: April 2024

Purpose: Cultural traditions as ancestral heritage contains local wisdom that can be utilized in community empowerment with communication technology to improve welfare.

Methods: This research inventories the relevance of Sundanese cultural values to digital civilization. The type of research is qualitative research. The data collection techniques used are in-depth interviews, observation, and document analysis.

Results and Conclusion: The results of this study state that local wisdom can be explored scientifically from a cultural product, with in-depth interpretation. As a cultural product, cultural traditions contain various things related to the life and livelihood of the owner community, such as value systems, beliefs and religions, social norms, work ethics, and even the way social dynamics take place.

Research implications: West Java Province, Indonesia occupies the highest positions reaching 16.4 million with an internet penetration rate of 36%. The majority of West Java people are Sundanese ethnic that have the noble values of cultural traditions and are used to regulate the Sundanese community order.

Originality/value: It is significant for this local wisdom to be actualized again in the current era, and it is the basis for the view that everyone has ethical boundaries in seeing, hearing, and speaking, especially in verbal traditions.
Access to the European cultural heritage of settlements and towns in the Danube macro-region through interoperable strategies digital transformation
Authors: ANATOLIE Babin , PRUS Elena , MARGINEANU Elena 
Published: April 2024

Tangible cultural heritage is a strategic resource for the development of rural and urban settlements. Cooperation with stakeholders from EU countries and regions within the Danube macro-region, such as cultural heritage institutions and competent authorities, allows to agree on the preparation and adaptation of compatible digital innovation strategies in local initiative groups in the Republic of Moldova and Ukraine, as well as on impact mapping through a set of pan-European socio-economic indicators. Objectives of the study: to analyse the available European best practices and methodology for adaptation in the integration of the regions of the Republic of Moldova and Ukraine in the interregional innovation partnership on the smart specialisation "Cultural and Creative Regional Ecosystems" (CCRE-S3) [1]. The overall horizontal objective of the integration into the platform should be to add value to the common characteristics of the cultural and creative sector and to create a permanent discovery mechanism that will carry out activities to identify strategic investments and the use of innovation transfer tools. Previous works: previous concept, research and experience are described in the articles [2] and [3]. Approach: European benchmarking, comparative analysis, bibliographic research. Outcome: recommendations aimed at stimulating new ideas and opportunities related to cultural and creative experiences for local communities and residents by involving several groups of professions that use, apply and implement new technologies in the cultural and creative industries sector. The European Programmes provide resources to support their implementation. In this way, the Danube Strategy participating States [4], by supporting partnerships between the cultural heritage sector and other sectors such as higher education and vocational education and training, creative industries and sustainable cultural tourism, will be able to stimulate innovation for new services and applications in their regions.
التنافس الدبلوماسي للدول الكبرى على المنطقة العربية
Authors: د.زيد احمد بيدر  , أ.د. رياض مهدي الزبيدي  
Published: April 2024

انعكست ظاهرة التنافس الدولي على المنطقة العربية، على ما تشهده المنطقة من تحولات سياسية وأمنية، والتي يرجع محاولة فهمها وتحليلها الى ما تشهده تفاعلات الدول الكبرى تجاه المنطقة العربية من تنافس في سبيل تدعيم نفوذها ومصالحها في المنطقة، وحاولت من اجل ذلك استثمار المتغيرات في المنطقة العربية في سبيل خلق مناطق نفوذ جديدة أو إرجاع مناطق نفوذ سابقة، واعتمدت الدول المتنافسة بشكل كبير على الأدوات الدبلوماسية لخلق شرعية تتيح لها التدخل في المنطقة، أو ممارسة الضغط والتأثير على المنطقة العربية، وبالشكل الذي يجعل مسار الأزمات والأحداث في المنطقة يسير وفق أهدافها، وشكلت المتغيرات في المنطقة العربية فرصة وتحدي للأطراف الدولية المتنافسة بنفس الوقت، إذ مثلت فرصة لبعض القوى الدولية للعمل على زيادة نفوذها في المنطقة العربية على حساب الأطراف الدولية المتنافسة الأخرى، وساهمت هذه المتغيرات أيضا في تهديد مصالح ومناطق نفوذ القوى الدولية الأخرى، وتعد ثورات الربيع العربي وتصاعد نشاط الجماعات الإرهابية من ابرز المتغيرات التي ساهمت في زيادة التفاعلات التنافسية للدول الكبرى في المنطقة العربية، إذ عملت الدول الكبرى على استثمارها بالشكل الذي يضمن تحقيق مصالحها في المنطقة، ورغم توظيف الأطراف المتنافسة مختلف الأدوات الدبلوماسية والاقتصادية والعسكرية في سبيل الوصول الى أهدافها، لكن اعتمدت بشكل كبير على الأدوات الدبلوماسية، للحصول على الشرعية الدولية، التي تتيح لها التدخل واستخدام جميع الأدوات بما فيها الأدوات العسكرية.
Early “Red Flags” in hospitalized patients with COVID-19
Authors: Malinovskiy V. A. , Fedosenko S. V. , Semakin A. V. , Dirks I. I. , Arzhanik M. B. , Semenova O. L. , Starovoitova E. A. , Vinokurova D. A. , Agaeva S. A. , Boldyshevskaya M. A. , Selikhova E. M. , Korepanov V. A. , Khalyavin S. A. , Nesterovich S. V. , Zima A. P. , Fedotova M. M. , Chernyavskaya G. M. 
Published: April 2024

Relevance. Among the studies during the COVID-19 pandemic, a special role is played by studies examining the prognostic value of clinical, laboratory and instrumental markers in patients. Biomarkers with absolute sensitivity and specificity for predicting the outcome of a new coronavirus infection have not been identified yet.Aim: To identify early clinical and laboratory predictors of severity and mortality in hospitalized patients with COVID-19 and to evaluate the effectiveness of the pharmacotherapy in outpatient and early hospital settings.Methodology and research methods. A retrospective, comparative study was carried out. Medical data from 745 adult patients with COVID-19, hospitalized in the respiratory hospital of the Siberian State Medical University (Tomsk) from 05/16/2020 to 09/30/2020 were included. The main group consists of patients who were discharged from the hospital. The comparison group included patients with a fatal outcome of the disease.Results. The group of deceased patients was characterized by older age and a greater number of comorbid diseases (р < 0.0001), the presence of pneumonia during the year preceding COVID-19 (р < 0.0001) and risk factors for the development of Pseudomonas aeruginosa infection (р < 0.005). Early admission to the hospital (р = 0.0110), severe dyspnea (р < 0.0001) with a decrease in oxygen saturation below reference values (р < 0.0001) are also associated with the risk of a fatal outcome. Anosmia was significantly more common in the group of surviving patients.The number of platelets, the absolute number of lymphocytes, amounts of total protein, albumin (р < 0.0001), sodium (р = 0.0013) in the first 48 hours of hospitalization in the main group were significantly higher. The number of leukocytes (p = 0.0078), neutrophils (p < 0.0001), neutrophil-lymphocyte ratio (p < 0.0001), concentrations of glucose, aspartate aminotransferase, urea, creatinine, C-reactive protein and lactate dehydrogenase were significantly lower in the main group. Serum procalcitonin levels > 0.5 ng/ml were 5 times higher in deceased patients during early period of hospitalization.Conclusion. Clinical, anamnestic and laboratory factors were identified through this study. These factors may be useful in the early period of hospitalization for accurate assessment of risks of severe ill, effective disease management and reduction of mortality in hospitalized patients with COVID-19.
Ultrasound indicators of blood flow in the eyes and orbits at different durations of type 1 diabetes mellitus in childhood and adolescence
Authors: Fomina S. V. , Zavadovskaya V. D. , Samoylova Iu. G. , Koshmeleva M. V. , Kachanov D. A. , Trifonova E. I. , Zorkaltsev M. A. , Yun V. E. 
Published: April 2024

Diabetic retinopathy is a complication of type 1 diabetes mellitus with high social significance, especially in childhood and adolescence.Aim: To evaluate ultrasound indicators of retrobulbar blood flow at different durations of type 1 diabetes mellitus in childhood and adolescence.Material and Methods. Ultrasound examinations were performed in 70 patients with type 1 diabetes mellitus aged from 5 to 18 years, with disease duration of up to 5 years, from 5 to 10 years, and more than 10 years. The analysis included an assessment of the linear velocity of blood flow and the index of peripheral resistance in the ophthalmic arteries, central arteries and retinal veins, posterior short ciliary arteries, and ophthalmic veins at different times of the duration of type 1 diabetes mellitus.Results. The study revealed a decrease in blood flow velocity in the central retinal arteries, in the posterior short ciliary arteries with an increase in the duration of type1 diabetes mellitus. The greatest decrease in blood flow velocity was recorded in the group with duration of diabetes mellitus of more than 10 years.Conclusion. The obtained data on a decrease in blood flow velocity in the retrobulbar arteries can be used for the assessment and dynamic monitoring of early disorders of the blood supply to the eye and orbit in patients with type 1 diabetes mellitus in childhood and adolescence.
Polymorphic locus rs8023580 NR2F2-AS1 is associated with breast cancer risk in residents of Central Russia
Authors: Pasenov K. N. , Ponomarenko I. V. , Churnosov M. I. 
Published: April 2024

Breast cancer (BC) is the most common hormone-dependent genetically determined cancer among women. The level of “active” sex hormones in the body, the connection of which with breast cancer is beyond doubt, is determined by the content of the protein transporting sex hormones (SHBG).Aim: To study associations of polymorphic loci linked with the level of SHBG at the full-genomic level of significance with the risk of developing breast cancer.Material and Methods. The work was carried out on a sample of 1,498 women, 358 of whom were BC patients, the control was 1140 individuals. Genotyping of four single nucleotide polymorphic loci (SNP) associated with the level of SHBG was performed according to previously performed genome-wide studies (GWAS): rs7910927 JMJD1C, rs4149056 SLCO1B1, rs8023580 NR2F2-AS1, rs12150660 SHBG. The method of logistic regression was used to search for associations.Results and Discussion. SNP rs8023580 of the NR2F2-AS1 gene is associated with the risk of BC developing. The presence of the CC genotype rs8023580 NR2F2-AS1in a woman has a protective value in the formation of the disease (CCvsTC+TT [recessive model]; OR = 0.58; 95%CI = 0.35–0.96; p = 0.033; pperm = 0.042). SNP rs8023580 NR2F2-AS1 is functionally significant in the liver: it is localized in the enhancer region, affects the level of methylation of the cg01739960 (hg38) genome region, affects the expression of the RP11-327J17.2 gene, determines the interaction of DNA with six transcription factors (Fo xd1,Foxl1,Foxq1,Mef2,PLZF,STAT), which are located in the cis-regulatory region of RNA polymerase II, specific for the DNA binding sequence, and determine the activity of DNA-binding transcription factors specific for RNA polymerase II, are involved in the processes of cellular differentiation and tissue development.Conclusion. The SHBG-enhancing CC genotype rs8023580 of the NR2F2-AS1 gene is a protective factor in the development of BC.
Numerical model of aneurysm formation in vascular grafts
Authors: Klyshnikov K. Yu. , Ovcharenko E. A. , Glushkova T. V. , Onishchenko P. S. , Rezvova M. A. , Kostyunin A. E. , Akentieva T. N. , Sogoyan N. K. , Barbarash L. S. 
Published: April 2024

Background. Using numerical modeling to study biomechanics of implantable devices for cardiovascular healthcare can help specialists understand underlying mechanisms of clinical complications caused by these devices.Aim: To describe the results of numerical modeling of aneurysm formation in vascular grafts based on the simulation of degradation of their mechanical properties.Material and Methods. The simulation was carried out using a three-dimensional computer model obtained by high-resolution computed tomography of the vascular graft “KemAngioProtez” (CJSC “NeoKor”, Russia). Using the 3D model obtained with a specialized script in the Abaqus/CAE environment (Dassault systems, USA), we have simulated the decrease in the elastic modulus (from 100 to 10%) with post-threshold stresses in the material and the accumulation of plastic strain.Results. Undergoing 150 loading cycles, the vascular wall in the model swelled up to 0.7 mm in the radial direction, and its mechanical properties degraded significantly (by 90% compared to baseline) due to prolonged pressure exposure. The value of maximum plastic deformation was 0.55%.Conclusion. Numerical modeling of graft mechanical properties degradation can assist in qualitative and quantitative assessment of the areas of aneurysm formation. The method makes it possible to visualize the swelling areas and can be used as a valuable tool to complement the existing approaches to studying vascular grafts, and biografts in particular.
Study of the biocompatibility of porous 3D-TiNi implants in vivo
Authors: Marchenko E. S. , Gordienko I. I. , Kozulin A. A. , Baigonakova G. A. , Borisov S. A. , Garin A. S. , Cherny S. P. , Choinzonov E. L. , Kulbakin D. E. 
Published: April 2024

Introduction. Porous TiNi alloys are widely used in medicine as osteoreplacement implants due to their unique properties of superelasticity and biocompatibility, but their clinical use is severely limited by time-consuming manual fabrication and the inability to create precise geometries. Reconstructive surgery for the replacement of bone defects requires biocompatible endoprostheses of individual shape and complex geometry. The use of porous 3D-TiNi implants can be a solution to many problems in traumatology and bone oncology.Aim: To evaluate the possibility of using porous 3D-TiNi implants in osteoplastic surgery based on a study of the structure and biocompatibility of the material under in vivo conditions.Material and Methods. Porous samples in the form of cones and a single implant for maxillofacial surgery were prepared from TiNi powder by selective laser melting. To print an individual implant for maxillofacial surgery, the personal data of the patient at the Oncology Research Institute were used. The macrostructure, elemental and phase composition of porous titanium nickelide samples were investigated using scanning microscopy and X-ray diffraction analysis. The biocompatibility of porous cone-shaped samples was evaluated in vivo using guinea pigs whose condition was analysed by CT scanning.Results. Structural studies of porous titanium nickelide samples showed that selective laser melting can be used to obtain a continuous porous structure with strong contact bridges between particles of a three-phase powder. In vivo testing of the cone-shaped implants showed no local inflammatory changes, rejection or deformation of the hind limb axes of the experimental animals. The basic feasibility of fabricating a custom implant of complex geometry from TiNi powder using selective laser melting according to a patient’s MSCT data was demonstrated.Conclusions. Porous 3D-TiNi implants obtained by selective laser melting showed high biocompatibility under in vivo conditions. An experimental study confirmed the efficacy and ease of use of 3D TiNi implants, their excellent self-fixation in bone tissue, and bone tissue augmentation at the interface with the implant. The macrostructure, chemical and phase composition of the implant material was found to be close to traditional porous TiNi alloys. It was shown that the method of selective laser melting makes it possible to create complex geometric defects in bone tissue from TiNi.
Recurrent pulmonary embolism and non-ST elevation acute myocardial infarction: current problems of diagnosis and treatment (clinical case)
Authors: Poponina T. M. , Poponina Yu. S. , Ryabov V. V. 
Published: April 2024

A clinical case of a patient with recurrent pulmonary embolism (PE) and non-ST elevation acute myocardial infarction (NSTEMI) is presented. Underestimation of the history data, the clinical course of non-massive pulmonary embolism under the mask of syncope, eventually led to the development of massive pulmonary embolism and clinical death of the patient. The article discusses non-massive PE masks, principles of treatment and secondary prevention of venous thromboembolic complications in a patient with acute NSTEMI.
Nosocomial infections: a look at the problem in the context of the global threat of antibiotic resistance (review)
Authors: Perfileva D. Yu. , Miroshnichenko A. G. , Kulikov E. S. , Boykov V. A. , Nesterovich S. V. , Perfilev V. Yu. 
Published: April 2024

Antibiotic resistance poses a serious threat to public health. The problem of nosocomial infections is inextricably linked with antibiotic resistance. Nosocomial infections in most cases are caused by the formation and spread of hospital strains that are resistant to antibacterial drugs. Nosocomial infections caused by multidrug-resistant microorganisms increase healthcare costs, lengthen hospital stays, and lead to extremely poor patient outcomes. The article systematizes data on the prevalence of nosocomial infections and examines the problem of antibiotic resistance of leading nosocomial pathogens. Approaches to monitoring and management of antibiotic resistance and epidemiological surveillance of nosocomial infections are analyzed. A promising area of research in public health is considered – osocomial infections associated with previous hospitalization.
Clinical and psychological associations and coping strategies for personality type D and depression in patients with coronary artery disease
Authors: Sumin A. N. , Shcheglova A. V. , Anchkova M. I. , Fedorova D. N. , Shabalina K. A. 
Published: April 2024

The comorbidity of manifestations of psychological distress and cardiovascular diseases is complex. The degree of impact of psychological stress on the patient depends on the possibilities of the adaptive potential of the individual in the environment.Aim: To study the cognitive assessment of stress, coping strategies and clinical and psychological associations in personality type D and depression in patients with coronary artery disease (CAD).Material and Methods. The study included 112 CAD patients. The DS-14 questionnaire was used to determine personality type D.To determine the level of depression the hospital scale HADS (Hospital Anxiety and Depression Scale). To assess coping strategies, the questionnaires “Methods of Coping Behavior” and “Indicator of Stress Coping Strategies” were used. Difficult life situation (DLS) assessment was determined using the “Cognitive Assessment of DLS” methodology. The questionnaire “Types of Orientations in Difficult Situations” was used to study orientations in DLS.Results. Patients were divided into groups based on manifestations of psychological distress: with type D (n = 40), without type D (n = 72); with depression (n = 48) without depression (n = 82). In type D, there was a more frequent assessment of the situation as out of control (12.0 ± 4.6 points versus 11.0 ± 4.6 points, p = 0.049) and orientation towards losses in difficult situations (17.0 ± 4.1 points 15.5 ± 5.1, points, p = 0.016). In depression, less pronounced desire for difficulties (19.0 ± 5.0 points versus 23.0 ± 5.9 points, p = 0.006), orientation towards opportunities (15.5 ± 3.2 points versus 18.0 ± 3.5 points, p < 0.001). In type D, the strategies “Escape-avoidance” (p = 0.05) and “Self-control” (p = 0.04) were used more often. In depression, the strategies “Problem resolution” (p = 0.02), “Search for social support” (p < 0.001) and “Avoidance” (p = 0.02) were more often used, less often – “Confrontational coping” (p = 0.001).Conclusion. Differences in cognitive assessment and coping strategies were revealed in patients with coronary artery disease in personality type D and the development of depression symptoms. This study emphasizes the need for individualized behavioral interventions for patients with coronary artery disease with manifestations of psychological distress.
Algorithm for personalization of diet therapy in patients with atrial fibrillation and obesity based on metabolic status assessment
Authors: Romanova T. A. , Bogdanov A. R. , Fedulaev Yu. N. 
Published: April 2024

Aim: To develop an algorithm for personalizing the diet therapy of patients with obesity and atrial fibrillation (AF) based on the assessment of the metabolic status.Material and Methods. The study included 100 patients with grade III obesity and paroxysmal AF. All subjects had nonvalvular AF. Anthropometric parameters, actual nutrition, bioimedance analysis of body composition, basal metabolic rate (BMR) were assessed.Results. Changes in basal metabolism by gender were identified. In women – a decrease in the rate of carboydrate oxidation (CHO) (by 27 ± 12.2%, p < 0.05), an increase in fat oxidation (by 48,58 ± 14.6%, p < 0.01). In men – a decrease in BMR (by 26,23 ± 13.6%, p < 0.05), CHO (by 57,18 ± 18.1%, p < 0.01) and protein (by 28,06 ± 12.9%, p < 0.05), increased rate of fat oxidation (by 31,42 ± 10.0%, p <0.05). A hyperphagic pattern of actual nutrition has been established: excess daily energy intensity (by 16–44%), excess of daily intake of proteins (by 34–54%), fats (by 17% in women) and carbohydrates (by 57–72%, p < 0.05). An excessive amount of saturated fat, cholesterol, and added sugar was revealed in the diet. A deficiency in vitamin D intake was found (by 8–16%, p < 0.05). The maximum daily energy requirement for 95% of women is within 2250 kcal/day, for men – 2950 kcal/day.Conclusion. Metabolic status disorders serve as factors of hemodynamic overload, humoral and electrical dysfunction of the heart. Diet therapy is a powerful component in the treatment and prevention of AF. It is advisable to carry out an algorithm for individual correction of the chemical composition and energy value of diet therapy taking into account the optimal metabolic corridor of needs, enriching the diet with vitamin D, eliminating added sugar, cholesterol, sodium, phosphorus, and sources of vitamin K.