bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pressure‐driven perfusion culture microchamber array for a parallel drug cytotoxicity assay
Authors: Sugiura Shinji , Edahiro Jun‐ichi , Kikuchi Kyoko , Sumaru Kimio , Kanamori Toshiyuki 
Published: February 2008

AbstractThis article reports a pressure‐driven perfusion culture chip developed for parallel drug cytotoxicity assay. The device is composed of an 8 × 5 array of cell culture microchambers with independent perfusion microchannels. It is equipped with a simple interface for convenient access by a micropipette and connection to an external pressure source, which enables easy operation without special training. The unique microchamber structure was carefully designed with consideration of hydrodynamic parameters and was fabricated out of a polydimethylsiloxane by using multilayer photolithography and replica molding. The microchamber structure enables uniform cell loading and perfusion culture without cross‐contamination between neighboring microchambers. A parallel cytotoxicity assay was successfully carried out in the 8 × 5 microchamber array to analyze the cytotoxic effects of seven anticancer drugs. The pressure‐driven perfusion culture chip, with its simple interface and well‐designed microfluidic network, will likely become an advantageous platform for future high‐throughput drug screening by microchip. Biotechnol. Bioeng. 2008;100: 1156–1165. © 2008 Wiley Periodicals, Inc.
Direct Evidence for ArOS Bond Cleavage upon Inactivation of Pseudomonas aeruginosa Arylsulfatase by Aryl Sulfamates
Authors: Bojarová Pavla , Denehy Emma , Walker Ian , Loft Karen , De Souza David P. , Woo L. W. Lawrence , Potter Barry V. L. , McConville Malcolm J. , Williams Spencer J. 
Published: February 2008

AbstractPseudomonas aeruginosa arylsulfatase catalyses the cleavage of aryl sulfates and is an excellent model for human estrone sulfatase, which is implicated in hormone‐dependent breast cancer. Aryl sulfamates are inactivators of sulfatases; however, little is known about their mechanism. We studied the inactivation of Pseudomonas aeruginosa arylsulfatase A by a range of aryl sulfamates, including the clinical agent 667COUMATE (STX64) used to inactivate estrone sulfatase. Inactivation was time dependent, irreversible, and active‐site directed, consistent with a covalent modification at the active site. In terms of the kinetic parameters of inactivation kinact and Ki, Ki values are in the micromolar to nanomolar range, and the inactivation half‐life is less than 30 s. A Brønsted plot of kinact/Ki has a steep slope (βlg=−1.1), which implies that the transition state for the first irreversible chemical step of inactivation involves a high degree of charge transfer and cleavage of the ArOS bond. Detection of the released phenol and titration of the residual activity showed the stoichiometry of inactivation to be in the range 3–6, with the greatest values found for the most effective inactivators. Thus, multiple sulfamoylation events appear to occur during the inactivation process. These data provide valuable insight into the mechanism of sulfatase inactivation by sulfamates.
Molecular Pacman: Folding, Inclusion, and X‐ray Structures of Tri‐ and Tetraamino Piperazine Cyclophanes
Authors: Raatikainen Kari , Huuskonen Juhani , Kolehmainen Erkki , Rissanen Kari 
Published: February 2008

AbstractReaction of piperazine and 1,3‐bis(bromomethyl)‐2‐nitrobenzene under high‐dilution conditions yields cyclic trimeric trinitro, tetrameric tetranitro, and pentameric pentanitro piperazine cyclophanes. Reduction of the nitro groups with SnCl2 under acidic conditions produces the corresponding triamino and tetraamino piperazine cyclophanes. The solution studies of both nitro and amino piperazine cyclophanes at 30 °C by 1H NMR spectroscopy shows symmetrical structures owing to the fast conformational exchange, whereas the low temperature studies of the tetraamino piperazine cyclophane reveals interesting dynamic behavior that indicates additional intramolecular interactions. Careful crystallizations of the trimeric trinitro and triamino and the tetrameric tetraamino cyclophanes resulted in crystals suitable for X‐ray diffraction studies. In the crystalline state the amino‐functionalized cyclophanes manifest an extraordinary circular intramolecular hydrogen‐bonding network that leads to a fixed 3D structure. Hydrogen bonding in the triamino trimer leads to orientation of all three of the amino groups on the same side of the macrocycle, namely, the rcc conformation, whereas the tetraamino tetramer folds into a more compact shell‐like conformation. During the crystallization process one acetonitrile guest is enclosed into the cavity of the tetraamino cyclophane, which gives a crystalline inclusion complex with remarkable resemblance to the famous Pacman motif. The folding, which mimics the behavior of some cyclic peptides and pyrroles, is induced by intramolecular hydrogen bonding from the amino groups to the tertiary amine groups of the piperazines. The cavity of the tetraamino tetramer is markedly smaller than in the corresponding, but nonfolded, tetranitro tetramer and the guest/host volume ratio (packing coefficient) for the acetonitrile and the cavity is approximately 50 %, which indicates a good size match for acetonitrile inclusion.
ChemInform Abstract: Novel Intermetallics with the Ca11Ga7 Structure Type.
Authors: Wendorff Marco , Roehr Caroline 
Published: February 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Low Temperature Magnetic Properties of Layered Compounds: NaLnTiO4 (Ln: Sm, Eu, Gd, Tb, Dy, Ho and Er).
Authors: Ozawa T. C. , Ikoshi A. , Taniguchi T. , Mizusaki S. , Nagata Y. , Noro Y. , Samata H. 
Published: February 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: On the Feasibility of Phosphide Generation from Phosphate Reduction: The Case of Rh, Ir, and Ag.
Authors: Sweeney Christina M. , Stamm Kimber L. , Brock Stephanie L. 
Published: February 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Ionothermal Synthesis and Characterization of a Layered Propylene Diammonium Gallium Phosphate, (C3H12N2)6 [Ga12P16O64]×4.3H2O.
Authors: Lohmeier Sven‐Jare , Wiebcke Michael , Behrens Peter 
Published: February 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Soft‐Chemistry Synthesis of LiNbO3 Crystallites.
Authors: Liu Meinan , Xue Dongfeng , Li Keyan 
Published: February 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Combination of Lacunary Polyoxometalates and High‐Nuclear Transition‐Metal Clusters under Hydrothermal Conditions. Part 5. A Novel Tetrameric Cluster of [{FeIIFeIII12 (μ3‐OH)12 (μ4‐PO4)4} (B‐α‐PW9O34)4]22‐.
Authors: Zhao Jun‐Wei , Zhang Jie , Zheng Shou‐Tian , Yang Guo‐Yu 
Published: February 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: The Cluster Polymers ∞1[PtBi6Cl10] and ∞1[PtBi6Br10]: Synthesis, Thermochemistry, Crystal Structure and Chemical Bonding.
Authors: Steden Folker , Schmidt Peer , Wahl Bernhard , Isaeva Anna , Ruck Michael 
Published: February 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Dynamic Kinetic and Kinetic Resolution of N‐Boc‐2‐lithiopiperidine.
Authors: Coldham Iain , Patel Jignesh J. , Raimbault Sophie , Whittaker David T. E. 
Published: February 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis, Characterization, and Applications in Heck and Suzuki Coupling Reactions of Amphiphilic Cyclopalladated Ferrocenylimines.
Authors: Mu Bing , Li Tiesheng , Xu Wenjian , Zeng Guoliang , Liu Pingping , Wu Yangjie 
Published: February 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Direct Addition of Supercritical Alcohols, Acetone or Acetonitrile to the Alkenes Without Catalysts.
Authors: Kamitanaka Takashi , Hikida Tatsuyoshi , Hayashi Satoshi , Kishida Nobuhiro , Matsuda Tomoko , Harada Tadao 
Published: February 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Efficient Carbonylation Reactions in Phosphonium Salt Ionic Liquids: Anionic Effects.
Authors: McNulty James , Nair Jerald J. , Robertson Al 
Published: February 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Highly Efficient Microwave‐Accelerated Preparation of β‐Ketoimines.
Authors: Lee Dong Hwan , Park Sang‐Eon , Cho Kyuho , Kim Younsoo , Athar Taimur , Lee Ik‐Mo 
Published: February 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: One‐Pot Synthesis of β‐Amino Acid Derivatives via Addition of Bis(O‐Silyl) Ketene Acetals on Iminium Salts.
Authors: Moumne Roba , Denise Bernard , Parlier Andree , Lavielle Solange , Rudler Henri , Karoyan Philippe 
Published: February 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Dzhemilev Reaction for the Synthesis of Spiro[3.3]heptane and Spiro[3.4]octanes.
Authors: D'yakonov Vladimir A. , Finkelshtein Evgeniy Sh. , Ibragimov Askhat G. 
Published: February 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Efficient Soluble Polymer‐Supported Tartrate/Ti Catalyst for Asymmetric Oxidation of Prochiral Sulfides.
Authors: Gao Jinshan , Guo Hongchao , Liu Shangzhong , Wang Min 
Published: February 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: In situ Generation of Palladium Nanoparticles: A Simple and Highly Active Protocol for Oxygen‐Promoted Ligand‐Free Suzuki Coupling Reaction of Aryl Chlorides.
Authors: Han Wei , Liu Chun , Jin Zi‐Lin 
Published: February 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Tandem Ring Opening and Oximation of Ethyl 3‐Aroyl‐1‐cyano‐4‐hydroxy‐2,4,6‐triarylcyclohexanecarboxylate by Hydroxylamine.
Authors: Saravanan Sivaperuman , Babu Heeralal Vignesh , Muthusubramanian Shanmugam 
Published: February 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: A Highly Efficient Organic Sensitizer for Dye‐Sensitized Solar Cells
Authors: Park Nam‐Gyu , et al. et al. 
Published: February 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Ytterbium Triflate‐Assisted Catalytic Oxidative Cross‐Coupling of 2‐Naphthol Derivatives.
Authors: Habaue Shigeki , Temma Tomohisa , Sugiyama Yukihiro , Yan Pei 
Published: February 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: A Convenient Route to Prepare Isodicyclopentadiene—Precursor of 1,5‐Dihydro‐pentalene.
Authors: Burgos O F. , Chavez I. , Manriquez J. M. , Algeria S. 
Published: February 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Syntheses and Anticholinesterase Activities of Novel 3‐Aminocarbonylmethylene‐3‐methyl‐2,3‐dihydrobenzofuran‐5‐yl Carbamates.
Authors: Luo Weiming , Yu Qian‐sheng , Holloway Harold W. , Tweedie David , Parrish Damon , Brossi Arnold , Greig Nigel H. 
Published: February 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: New Approach to 4‐ and 5‐Aminopyrazole Derivatives.
Authors: Hassaneen Huwaida M. E. 
Published: February 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Palladium Catalyzed Synthesis of 4‐Substituted‐2‐phenylimidazoles from N‐Propargyl‐benzamidine.
Authors: Abbiati Giorgio , Arcadi Antonio , Canevari Valentina , Rossi Elisabetta 
Published: February 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis of 2‐Substituted Benzimidazoles by Iodine‐Mediated Condensation of Orthoesters with 1,2‐Phenylenediamines.
Authors: Zhang Zhan‐Hui , Li Jian‐Jiong , Gao Yuan‐Zhe , Liu Yu‐Heng 
Published: February 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: A Novel Method for the Synthesis of Highly Functionalized 3,4‐Dihydropyrimidin‐2(1H)‐ones Through the 1,4‐Addition on Pyrimidin‐2(1H)‐ones.
Authors: Shanmugam P. , Boobalan P. , Perumal P. T. 
Published: February 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Design and Synthesis of a Functionally Selective D3 Agonist and Its in vivo Delivery via the Intranasal Route.
Authors: Blagg Julian , et al. et al. 
Published: February 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Retro‐Ene Reactions in Heterocyclic Synthesis. Part 5. A Novel Synthetic Method for 1,3,5‐Triazine‐2,4(1H,3H)‐diones.
Authors: Ito Kunio , Sekiguchi Chiharu , Miida Asuka Wakai Hiroyuki , Ihara Shogo 
Published: February 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Aminocarbonylation Route to Tolvaptan.
Authors: Torisawa Yasuhiro , Furuta Takuya , Nishi Takao , Aki Shinji , Minamikawa Jun‐ichi 
Published: February 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Electrophilic Tellurolactonization of 1,2‐Allenic Phosphonates: A Facile and Efficient Synthesis of 4‐(Phenyltelluro)‐1,2‐oxaphosphol‐3‐ene 2‐Oxides.
Authors: Yuan Jingqi , Ruan Xiuxiu , Yang Yewei , Huang Xian 
Published: February 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Total Synthesis of the Novel seco‐Prezizaane Sesquiterpenoid (+)‐1S‐Minwanenone (I).
Authors: Methta Goverdhan , Shinde Harish M. 
Published: February 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Three New Lanostane Triterpenoids from Inonotus obliquus
Authors: Taji Sayaka , Yamada Takeshi , In Yasuko , Wada Shun‐ichi , Usami Yoshihide , Sakuma Kazuo , Tanaka Reiko 
Published: February 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Highly Diastereoselective Preparation of anti‐α,β‐Dialkyl β‐Amino Acids Containing Natural α‐Amino Acid Side Chains.
Authors: Capone Stefania , Pedatella Silvana , Guaragna Annalisa , De Nisco Mauro , Palumbo Giovanni 
Published: February 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Enantioselective Synthesis of (‐)‐Barrenazines A and B.
Authors: Martinez M. Montserrat , Sarandeses Luis A. , Sestelo Jose Perez 
Published: February 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Structures and Properties of One‐Dimensional Transition Metal Containing Coordination/Organometallic Polymers and Oligomers Built Upon Assembling Diphosphine and Diisocyanide Ligands
Authors: Harvey Pierre D. 
Published: February 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Intramolecular 1,3‐Dipolar Cycloaddition Reactions in Targeted Syntheses.
Authors: Nair Vijay , Suja T. D. 
Published: February 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.