bluuebunny/crossref_metadata_2025_split huggingface dataset:
Chemical properties and inhibitory activities of tyrosinase, α‐glucosidase, and urease from chloroform extract of Curcuma aromatica Salisb. rhizomes
Authors: Le Tho Huu , Bui Thinh Quang , Dang Phu Hoang , Nguyen Hai Xuan , Van Do Truong Nhat , Nguyen Mai Thanh Thi , Nguyen Nhan Trung 
Published: March 2024

Abstract"Nghệ trắng" has the scientific name of Curcuma aromatica Salisb., belongs to the Ginger family (Zingiberaceae), and its rhizomes are used to prevent aging, anti‐inflammatory, and improve skin. From the chloroform extract of C. aromatica, six known compounds, including (‐)‐hannokinol (1), (3R,5R)‐3,5‐diacetoxy‐1,7‐bis(4‐hydroxyphenyl)heptane (2), naringenin (3), 2‐(4‐(hydroxymethyl)phenyl)propan‐2‐ol (4), 5‐hydroxymethylfurfural (5), and bisacurone (6), were isolated. Structures of all compounds were elucidated by analyzing NMR data together with comparing them to references. All isolated compounds were found for the first time in the C. aromatia rhizomes grown in Vietnam. The results of bioactivity evaluation showed that naringenin (3) has an effect against tyrosinase and α‐glucosidase with the IC50 values of 96.4 and 248.2 μM, respectively. (‐)‐Hannokinol (1) is a moderate bioactivity ingredient capable to inhibiting α‐glucosidase and urease with the IC50 value of 216.4 and 244.4 μM, respectively. Consequently, these results suggest that chloroform extract of C. aromatica may be a practical therapeutic approach for diabetes, melanogenesis, and stomach ulcer treatment.
Effect of alkaline‐treated spent coffee grounds and compatibilizer on the mechanical properties of bio‐composite based on polypropylene matrix
Authors: Thanh Nguyen Ngoc , Tan Vu Minh , Trung Dang Huu , Huong Pham Thi Mai , Nhung Le Thi Hong , Ha Nguyen Manh , Van Ngo Thuy , Tung Nguyen Thanh , Thuy Nguyen Thi Thu 
Published: March 2024

AbstractIn this study, the effect of alkaline‐treated spent coffee grounds and compatibilizer on the mechanical properties of bio‐composite based on polypropylene (PP) matrix was investigated. After alkaline treatment, the surface of spent coffee grounds became rougher; hence the PP matrix could better adsorb and encapsulate the treated coffee grounds compared with that of untreated ones. The TGA analysis shows that the alkaline treated spent coffee grounds had better thermal properties than the untreated ones. When increasing the weight percentage of spent coffee grounds from 10 to 20, the tensile strength and flexural strength of PP‐based composite decreased. These mechanical properties of PP‐based composite containing treated coffee grounds were enhanced compared with that containing untreated coffee grounds due to the better dispersion of treated coffee grounds into the PP matrix. The presence of polypropylene‐graft‐maleic anhydride (PP‐g‐MA) compatibilizer at the content of 1, 3, and 5 wt% led to a significant increase the mechanical properties of PP‐based bio‐composites, reaching the highest tensile strength of 22.7 MPa and flexural strength of 17.3 MPa. Therefore, the alkaline‐treated spent coffee ground is a potential additive for producing bio‐composite with the advantages of being light and easy to naturally decompose.
A novel, eco‐friendly film preparation process for improving the stability of organometal halide perovskite in solar cells
Authors: Nguyen Thuy Thanh Thi , Nguyen Minh‐Hang , Nguyen Phi‐Hong , Nguyen Thuy Thanh Doan , Nguyen Tien Huu , Nguyen Phuong Tuyet 
Published: March 2024

AbstractA major challenge for outdoor uses of methylammonium lead halide (MAPbX3) solar cells is the poor durability of the perovskite film under humidity. This instability is due to limitations of the dipping or spin coating process in producing MAPbX3 films through a direct reaction between PbI2 and methylammonium iodide (MAI) in an organic solvent. In this study, we devised an eco‐friendly and cost‐effective method to fabricate MAPbX3 films using an aqueous solution of Pb(NO3)2 and MAI vapour. In both instances of using Pb(NO3)2 and PbI2, a perovskite layer with a tetrahedral structure was seen with a band gap of roughly 1.52‐1.54 eV. We discovered that the perovskite film grew at a slower rate with aqueous Pb(NO3)2 compared to that in PbI2 and disintegrated gradually at ambient temperature and 40% humidity. Compared to PbI2 films‐based solar cells under the same reaction time, those based on aqueous Pb(NO3)2 films showed remarkably higher durability (maintain 83% for Pb(NO3)2 films‐based, 78% for PbI2 films‐based after 720 hours) and greater photovoltaic efficiency with the photocurrent density of 10.1 mA.cm‐2, the voltage of 0.89 V, the fill factor of 0.82 and PCE of 7.4% which is higher than PbI2 cells 30%.
Method development for analysis 13 per‐ and polyfluoroalkyl acids in tap water by HPLC‐MS/MS
Authors: Tran Nhi Thi Yen , Tran Vui Thi Kim , Nguyen Mai Anh , Nguyen The Thai , Tran Phuong Hoang , Nguyen Phuong Nam , Quyen Do Thi Thuy , Hien To Thi 
Published: March 2024

AbstractThe purpose of this study was to develop a sensitive, accurate and simple method for analysis of 13 perfluoroalkyl acids (8 perfluoroalkyl carboxylic acids and 5 perfluoroalkyl sulfonic acids) in tap water by LC‐MS/MS. This paper focuses on optimizing the chromatographic instrumental operating parameters and the solid phase extraction conditions using HLB cartridges. Results from the method validation showed that the method has sub ng/L LOQs (0.10‐0.60 ng/L), quantitative recoveries at the concentrations near the LOQs (74.4‐122.8%) and high repeatability with acceptable %RSD (15.6‐38.3%). The analytical procedure was then applied to assess how significant the contamination of PFAAs in tap water of Ho Chi Minh City. Besides that, a new self‐made solid phase extraction material prepared by grafting an ionic liquid on silica was used to enrich the target analytes. Preliminary results show that the material based on 1‐octyl‐3‐(3‐(triethoxysilyl) propyl)‐1H‐imidazolium bromide has promising retention ability for these compounds, the recoveries on ionic liquid‐based materials ranged from 36.3‐69.0%.
Synthesis and antibacterial activities of some novel hybrid compounds based on 2‐mercapto‐3‐arylquinazolin‐4(3H)‐one scaffold bearing specific coumarin
Authors: Thuy Linh Bui Thi , Le Thien Phuoc , Chi Hien Dang , Thi Hai Ha Pham , Tien Cong Nguyen 
Published: March 2024

AbstractTwo series of novel hybrid compounds, in which a variety of 2‐mercapto‐3‐arylquinazolin‐4(3H)‐ones (3a‐d)/6‐bromo‐2‐mercapto‐3‐phenylquinazolin‐4(3H)‐one (9) act as fundamental moieties are incorporated in particular 3‐(2‐bromoacetyl)‐2H‐chromen‐2‐one (4) or 2‐chloro‐N‐(2‐oxo‐2H‐chromen‐3‐yl)acetamide (5) via alkylation of the thiol group in quinazolin‐4(3H)‐one ring, were synthesized. The key intermediates (3a‐d) and (9) were prepared by the reaction of anthranilic acid (1)/2‐amino‐5‐bromobenzoic acid (8) with carbon disulfide and appropriate aromatic amines in an alkaline medium. These compounds’ structures were confirmed by comparing their physical characteristics and spectral data to the earlier ones. Ten novel products (6a‐d, 7a‐d, 10, 11) were synthesized and the structures were determined by their IR, 1H‐NMR, 13C‐NMR and HR‐MS spectral data. Subsequently, their antimicrobial activities were estimated in vitro test against four bacterial strains including P. aeruginosa NRRL B‐14781 and E. coli NRRL B‐409 (Gram‐negative), B. cereus ATCC 10876 and L. monocytogenes ATCC 13932 (Gram‐positive), by agar well diffusion assay. The outcome showed that all hybrid compounds have potential inhibition of tested Gram‐negative bacteria. Compound (6d) revealed remarkable antibacterial effects on P. aeruginosa and E. coli growth. Besides, compounds (6a), (7a), (7d) and (10) have also inhibitory effects on B. cereus strain at tested concentrations. The compounds mentioned above contain the 3‐chlorophenyl/phenyl substituent at position 3 in the quinazoline ring.
A TD‐DFT/DFT study on the ESIPT and photophysical properties of symmetrical 2‐hydroxybenzilidene1,3‐diamines derivatives
Authors: Elroby Shaaban A. , Osman Osman I. , Jedidi Abdesslem , Hassan Walid I. , Aziz Saadullah G. , Hilal Rifaat 
Published: March 2024

AbstractDensity functional theory (DFT) and Time dependent density functional theory (TD‐DFT) methods are used to simulate the photoexcitation and emission of the symmetrical 2‐hydroxybenzilidene1,3‐diamine (HBDA) Schiff base and some of its derivatives in the gas phase and solution. Our aim here is to explore the details of Excited‐State Intramolecular Proton Transfer (ESIPT) which underlies the activity of HBDA molecules as fluorescent probes. The structures of HBDA in S0 and the S1 states are optimized utilizing the DFT and TD‐DFT methods, respectively. Geometric configurations, electronic spectra, frontier molecular orbitals, and potential energy surfaces have all been computed and analyzed for the purpose of interpreting the mechanism of ESIPT. The geometries and relative stabilities of 15 tautomeric forms and the corresponding isomers of the studied molecules have been identified and their relative stabilities are investigated. The potential energy profiles and intrinsic reaction coordinates (IRC) calculations along the proton transfer coordinates both in the ground and in the excited state are monitored as well. The impact of the donating (OMe) and withdrawing (NO2) groups on the single and double proton transfers are investigated both in the gas phase and solution.
Polycyclic aromatic‐based fluorescent probes: Color properties and fluorimetric detection of nitroaromatic explosives
Authors: Bal Mustafa , Köse Ayşegül 
Published: March 2024

AbstractDetection of nitroaromatic explosives (NAEs) is very important in terms of national security as well as the damage they cause to living things and the environment. The precision detection of these is a very important issue to reduce their harmful effects and take the necessary precautions. Electron‐rich polyaromatic fluorescent materials are highly sensitive and selective in the detection of NAEs in terms of their fluorometric quenching abilities. Three imine compounds (A‐C) containing pyrene, anthracene or naphthalene moieties were prepared and used as fluorescent probes for fluorescence detection of NAEs. The sensing abilities of materials characterized by traditional methods were investigated. The quenching‐increasing constant Ksv was calculated by using the Stern‐Volmer plot obtained from the interaction of materials with nitroaromatic. Limits of detection (LOD) values were calculated for the compounds using these data. While the quenching effect of nitro aromatic compounds was expected on fluorescent materials, increased emission was observed due to aggregation. Compound A was sensitive to Picric acid thanks to lowest LOD (38.59 μM), while compounds B and C nitrobenzene thanks to lowest LOD value (22.32 and 36.93 μM, respectively). In addition, color measurements (CIE standards) and color temperature (CCT) of the compounds were calculated.
Chemical constituents of the leaves of Fissistigma balansae
Authors: Tham Pham Thi , Thao Tran Thi Phuong , Tai Bui Huu , Trang Do Thi , Thanh Nguyen Ha , Thuy Ngo Thi Thanh , Chinh Pham The , Van Kiem Phan 
Published: March 2024

AbstractPhytochemical study on the leaves of Fissistigma balansae led to the isolation of one new sesquiterpene glycoside, (3S,6E)‐3‐O‐β‐D‐glucopyranosyl‐8‐hydroxy‐3,7,11‐trimethyldodeca‐1,6,10‐triene (1), and six known compounds, aromandendrane‐4β,10α‐diol (2), phloridzosid (3), astragalin (4), isoquercitrin (5), and rutin (6), acanthoside B (7). Their chemical structures were identified by HR‐ESI‐MS and NMR (1D and 2D) spectra. This is the first report of these compounds from F. balansae.
The Glauber reaction to manufacture potassium permanganate: An optimal balance between commercial efficiency and sustainability
Authors: Mousavi Aliyar 
Published: March 2024

AbstractThe spontaneous oxidation of aqueous potassium manganate to aqueous potassium permanganate, first carried out by the German alchemist of the 17th century Johann Rudolf Glauber, was used for the manufacture of potassium permanganate until it was replaced with the electrolytic oxidation of potassium manganate, which is the current state of the art. The reason for the replacement was that the method that is based on the Glauber reaction is commercially less efficient. In this minireview, the efficiency of the Glauber reaction was evaluated by equilibrium determinations and comparatively viewed in light of today's principle of sustainability. The manufacture of potassium permanganate through the method based on the Glauber reaction is taking a step in the direction of building a more sustainable world.
Identification of potential oligo‐1,6‐glucosidase inhibitors in Distichochlamys citrea M.F. Newman essential oil
Authors: Bui Thanh Q. , Hai Nguyen Thi Thanh , My Tran Thi Ai , Phu Nguyen Vinh , Quy Phan Tu , Triet Nguyen Thanh , Van Chen Tran , Pham Duy Toan , De Tran Van , Dat Ton That Huu , Nhung Nguyen Thi Ai 
Published: March 2024

AbstractDistichochlamys citrea M.F. Newman, a genus endemic to Vietnam, has been known by folk experiences for its biological potential, including antidiabetics. The essential oil was extracted and characterized by gas chromatography‐mass spectrometry for compositional specificity. The data was used as input for computational predictions. Gas chromatography‐mass spectrometry analysis revealed the presence of 23 natural components in the essential oil (C1‐C23); major constituents: α‐citral (C16; 21.19%), cineole (C7; 16.11%), β‐citral (C14; 16.03%), geranyl acetate (C20; 15.97%), geraniol (C15; 10.74%). Density functional theory calculation suggests C14 and C15 highly promising for intermolecular interactions by on their electronic configurations. Molecular docking simulation predicts the most effective inhibitors against PDB‐3AJ7 (oligo‐1,6‐glucosidase) into the order of ligand‐protein complexes: C15‐3AJ7 (DS ‐11.9 kcal.mol‐1) ≈ C14‐3AJ7 (DS ‐11.8 kcal.mol‐1) > C12‐3AJ7 (DS ‐11.5 kcal.mol‐1) > C11‐3AJ7 (DS ‐11.2 kcal.mol‐1) > C9‐3AJ7 (DS ‐11.0 kcal.mol‐1). All the components are expected to be biocompatible (by QSARIS physical properties) and safe for medicinal use (by ADMET pharmacokinetics and pharmacology). Altogether, the results encourage further consideration of D. citrea M.F. Newman essential oil for further wet antidiabetic tests, especially the specification on C14 (aka. β‐Citral) and C15 (aka. Geraniol).
Expeditions and Fieldwork in Earth Sciences
Authors: Klemun Marianne 
Published: March 2024

AbstractWhat do journeys, expeditions, and fieldwork mean in the context of earth sciences? What status do they have, and what is their specific contribution to the training and development of geology? These are the main questions that this chapter seeks to answer. In the first section of the contribution, we will explore the phenomenon of travel and expeditions from a general point of view. Then we will analyze it on three levels. First, the practice of field research will be examined on the basis of introductory books as a manifestation of the methodological development of geologists’ targeted travel (questions and instructions), which reached its peak between 1750 and 1840. It was during this period that geology emerged as a discipline in its own right. Introductory books detailing the aims and procedures of a fieldwork reflect the fact that field research was considered essential by contemporary scholars. Similarly, the geologist’s hammer was invented in the eighteenth century and became the everyday tool of geologists in the field and ultimately the emblem of the profession.The contribution identifies three thematic clusters that illustrate the heterogeneity of expeditions and fieldwork in the development of geology. First, both are essentially connected to practices. Second, we have to explore the question of space and place in relation to expeditions and fieldwork, and third, the interplay between practices and scientific discourse, or theory and fieldwork (observation), needs to be analyzed. All three perspectives help us understand what was specific to the science of geology in terms of fieldwork and expeditions that also involved other sciences.
Medienberichterstattung über Nutztierhaltung: Wahrnehmungen und Bewertung in der deutschen Bevölkerung
Authors: Bardusch Bea , Schulze Walgern Anna , Christoph-Schulz Inken , Mergenthaler Marcus 
Published: March 2024

ZusammenfassungDie Berichterstattung der Medien über die landwirtschaftliche Nutztierhaltung erfüllt eine doppelte Funktion: Einerseits fungiert sie als wichtige Verbindung zwischen der landwirtschaftlichen Nutztierhaltung und der Öffentlichkeit. Andererseits wird die Medienberichterstattung als potenzielle Ursache für wachsende Unterschiede und als Einflussfaktor für kritische Haltungen in der Bevölkerung angesehen. Im Jahr 2022 wurde daher eine repräsentative Umfrage unter Bürgerinnen und Bürgern in Deutschland durchgeführt, um zu untersuchen, wie verschiedene demografische Gruppen die Medienberichterstattung über die landwirtschaftliche Nutztierhaltung wahrnehmen und bewerten. Die Ergebnisse zeigten signifikante Zusammenhänge zwischen soziodemografischen Merkmalen und der Bewertung der Medienberichte. Insbesondere Frauen und jüngere Personen tendieren dazu, die Medienberichterstattung und die landwirtschaftliche Nutztierhaltung kritischer zu bewerten. Im Gegensatz dazu nehmen Männer und ältere Personen die landwirtschaftliche Nutztierhaltung tendenziell positiver wahr, als sie in den Medien dargestellt wird.
Preoperative docetaxel, cisplatin, and 5-fluorouracil for resectable locally advanced esophageal and esophagogastric junctional adenocarcinoma
Authors: Hirose Toshiharu , Yamamoto Shun , Honma Yoshitaka , Yokoyama Kazuki , Hirano Hidekazu , Okita Natsuko , Shoji Hirokazu , Iwasa Satoru , Takashima Atsuo , Ishiyama Koshiro , Oguma Junya , Daiko Hiroyuki , Maeda Shin , Kato Ken 
Published: March 2024

Abstract
Background
Chemotherapy consisting of 5-fluorouracil, leucovorin, oxaliplatin, and docetaxel is the standard perioperative treatment for resectable esophageal adenocarcinoma and esophagogastric junctional adenocarcinoma (EGJ-AC) in Western countries. Meanwhile, preoperative chemotherapy consisting of docetaxel, cisplatin, and 5-fluorouracil (DCF) has been developed for esophageal squamous cell carcinoma in Japan. However, there are few reports on the safety and efficacy of preoperative DCF for resectable EGJ-AC in the Japanese population.

Methods
Patients with histologically confirmed resectable EGJ-AC who received preoperative DCF (docetaxel 70 mg/m2 and cisplatin 70 mg/m2 on day 1 and continuous infusion of 5-fluorouracil 750 mg/m2/day on days 1–5 every 3 weeks with a maximum of three cycles) between January 2015 and April 2020 were retrospectively evaluated. We assessed the rates of completion of ≥ 2 courses of DCF and R0 resection, histopathological response, progression-free survival (PFS), overall survival (OS), and adverse events.

Results
Thirty-two patients were included. Median follow-up was 28.7 (range, 5.2–70.8) months and median age was 63 (range, 42–80) years. Twenty-one patients (66%) had a performance status of 0. The proportions of clinical stage IIA/IIB/III/IVA/IVB disease were 3%/0%/44%/44%/9%, respectively. The treatment completion rate was 84%. A histopathological response of grade 1a/1b/2/3 was obtained in 58%/26%/13%/3% of cases. Median PFS was 40.7 months (95% confidence interval 11.8-NA). Median OS was not reached (80.8% at 3 years). Grade ≥ 3 adverse events were observed in 63% of cases (neutropenia, 44%; febrile neutropenia, 13%). No treatment-related deaths occurred.

Conclusions
Preoperative DCF for resectable EGJ-AC was well tolerated and has promising efficacy.
Multilateral indices in official price statistics and a new additive splicing method
Authors: Knížat Peter , Glaser-Opitzová Helena , Furková Andrea , Vojtková Mária 
Published: March 2024

AbstractA substitution of the traditional data sources allows National Statistical Institutes to collect large samples of product items with corresponding prices recorded over more frequent time periods. For some product categories, a frequent replacement of product items requires a dynamic approach to define a product sample that can be achieved by a monthly update of the sample. In a month-on-month comparison of price changes, bilateral indices must be chained that can lead to a chain drift bias. Multilateral methods are designed to reduce the chain drift, albeit not completely eliminate it. A disadvantage of multilateral methods is its ambiguous interpretability and a revision problem. The main objective of this paper is to show an implementation of multilateral methods for official price statistics in practice. The multilateral GEKS method is decomposed into elementary components that identifies the effect of successive price relatives used in its compilation. An importance of the decomposition is shown when interpreting the GEKS index in the context of official price statistics. We demonstrate that it can lead to an inaccurate public dissemination of the consumer price index. Moreover, we propose a new method for the splice extension that is required to avoid the revision of previously published indices. The method uses a Stein-type shrinkage estimator for the splice extension that is applied additively to the last published index. In the empirical study, we use web scraped data, which are obtained from the Slovak market, for comparison of bilateral and multilateral indices.
The Impact of Preoperative Dexamethasone Administration on Quality of Recovery Following Laparoscopic Sleeve Gastrectomy: A Prospective Observational Study
Authors: Taflan Mehmet Gokhan , Ustun Yasemin Burcu , Turunc Esra , Kaya Cengiz , Dost Burhan , Bilgin Sezgin , Ozdemir Emine , Ozbalci Gokhan Selcuk 
Published: March 2024

Abstract
Introduction
Recovery from anesthesia is complex and affected by multiple factors. In patient with obesity, the increased prevalence of anxiety and depressive disorders poses a challenge in achieving optimal patient satisfaction. Therefore, strategies to enhance the quality of recovery are crucial for this population. This study aimed to investigate whether administration of dexamethasone to patients undergoing laparoscopic sleeve gastrectomy (LSG) could improve recovery outcomes.

Methods
This prospective observational study was conducted at a tertiary university hospital in Samsun, Turkey. Thirty patients who received dexamethasone prior to LSG (group D) and 30 patients who did not (group C) were included with convenience sampling method. The quality of recovery was assessed using the Quality of Recovery 40 questionnaire (QoR-40). The primary outcome measure was the QoR-40 score at 24 h postoperatively.

Results
The dexamethasone group showed a significant improvement in QoR-40 scores (185.4 ± 6.0 vs. 172.0 ± 8.4, p < 0.001), exhibited reduced morphine consumption (11.8 ± 7.8 vs. 21.8 ± 10.9 mg, p < 0.001), opioid demand count (21.50 [9.50–49.00], p = 0.001), the number of patient used antiemetic drug (1 vs. 22, p < 0.001), and achieved earlier mobilization (3 [3–4] vs. 3 [3–4] h, p < 0.0001). However, no significant differences were observed between the two groups concerning intraoperative complications, postoperative wound infections, or time to discharge.

Conclusions
In patients undergoing laparoscopic sleeve gastrectomy, preoperative dexamethasone administration was associated with improved the recovery quality after discharge and reduced early postoperative need for antiemetic medications.

Graphical Abstract