bluuebunny/crossref_metadata_2025_split huggingface dataset:
(PM-14) THE USE OF VIBRATIONS IN FEMALE SEXUAL DYSFUNCTIONS: NARRATIVE REVIEW OF THE LITERATURE
Authors: Maia Fontes L I , da Costa Merino D , Fernandes Torres T , Castiglione M , Pavione Rodrigues Pereira R , Tanaka C 
Published: March 2024

Abstract

Introduction
There are several aspects that involve the sexual function of an individual, such as biological, psychological and interpersonal factors. Based on this, symptoms of female sexual dysfunction are classified according to the response phase of the affected sexual cycle. In physiotherapy there are some resources that are used for the treatment of sexual dysfunctions, including vibration, which is used with the aim of improving muscle condition and vascularization, but the real effects of applying this technique in the treatment are not known. of sexual dysfunctions. Thus, the objective of this study was to identify evidence on the benefits of vibration in female sexual dysfunctions.

Methodology
The PubMed and VHL databases were searched according to a search strategy defined by PICOS: ((((sexuality) OR (sexual dysfunction)) OR (pelvic floor disorders)) OR (women's health)) AND (vibration), which included systematic reviews, meta-analyses and clinical trials from 2012 to 2022 that approached vibration as a resource investigated or used in female sexual dysfunctions. Other study designs were excluded, as well as those that did not use vibration as a resource or that were aimed solely at the male audience.

Results
A total of 89 articles were found, of which 83 were excluded for not meeting the inclusion criteria; six articles were selected to compose this review. Among the selected articles, three brought vibration as a purely evaluative resource, and three articles also looked for evidence on the use of vibration as a treatment for female sexual dysfunctions.

Conclusion
No studies were found in which vibration has been used as a therapeutic resource in female sexual dysfunctions, which opens precedents for future studies in this regard.

Financing
No conflict.
(PM-16) DILATORY THERAPY IN WOMEN UNDERGOING RADIOTHERAPY FOR THE TREATMENT OF PELVIC CANCER
Authors: Caiano dos Santos B , Montagnini Mendonça L , Cordeiro Gomes V , Estevão A , Nunes Silva Bahia C , Castiglione M 
Published: March 2024

Abstract

Introduction
Pelvic radiotherapy is a treatment for gynecological and anorectal cancer, with side effects including vaginal fibrosis, dryness, adhesions and strictures. Rehabilitation aids may prevent or minimize post-radiotherapy vaginal changes and subsequent decline in sexual functioning, which could reduce distress.

Objective
To present the effects of dilator therapy on vaginal changes in women with pelvic cancer undergoing radiotherapy treatment.

Methods
This is an integrative review of the literature and surveys were carried out in the electronic databases PubMed and PEDro. The search terms used were: “Vaginal Dilator”, “Pelvic Neoplasm”, “Brachytherapy” and “Radiotherapy”. Only randomized clinical trials and observational studies were considered. Data collection was carried out between March and May 2022.

Results
21 studies were found, seven of which met the established criteria and agreed with the proposed objective. Subsequently, a manual search was carried out, where two more studies were found. Finally, this review was composed of nine studies. It was observed that the vaginal dilator after radiotherapy is beneficial, reducing the frequency and severity of vaginal stenosis, thus improving the quality of sexual life of women. However, it is important to highlight that psychosocial education programs are also important and cause positive effects in this population. Strategies related to promoting treatment adherence remain necessary due to taboos related to the use of dilators.

Conclusion
Dilator therapy is effective in reducing vaginal stenosis and improving the quality of sexual life of women undergoing radiotherapy for pelvic cancer.

Financing
No conflict.
(PM-20) INFLUENCE OF RELIGION ON FEMALE SEXUALITY: REVIEW OF NARRATIVE LITERATURE
Authors: Jardelina Muniz Augusto Silva F , da Costa Merino D , Fernandes Torres T , Castiglione M , Pavione Rodrigues Pereira R , Tanaka C 
Published: March 2024

Abstract

Introduction
Sexuality influences thoughts, feelings, actions and interactions and therefore also affects our physical and mental health. It is a complex part of life, shaped by many factors, including religious ones. Religiosity can guide the sexual and loving experience, directly influencing the individual's sexual understanding, such as the use or not of condoms during sexual practice. Therefore, the present study aims to identify in the literature the influence of religion on female sexuality.

Methodology
A narrative review of the literature was carried out in the PubMed database. Articles published in English, Spanish, Portuguese and Arabic from January 2017 to December 2022 were included, such as: clinical trials, meta-analysis and systematic review, which exclusively addressed female sexuality and religion. Studies that addressed male sexuality were excluded.

Results
74 articles were found, of which 28 were selected for reading according to the summary and 10 studies met the inclusion criteria and were analyzed. Most of the studies were on the Muslim, Islamic and Christian religions. Important points related to religious beliefs were identified, such as non-use of contraceptive methods, lack of knowledge about reproductive health, religious conflicts, marital status, virginity, sexual submission and menstrual taboos that negatively influence the quality of sexual life of religious women. . Studies with greater methodological rigor are needed to address this important issue.

Conclusion
This review showed that religion can have an adverse impact on the sexual health and quality of life of Islamic, Christian and Muslim women. Highlighting the need to conduct research in this area to understand and address this relationship.

Financing
No conflict.
(PM-22) THE UTILIZATION OF SOCIAL MEDIA AS A PSYCHOPEDAGOGICAL TOOL IN SEXUAL HEALTH WITH A FOCUS ON PARAPHILIAS
Authors: Braga C , Vasconcelos dos Santos L A , Sampaio M , Bremberger LdL , Medeiros J V , Torres de Sá Urtiga Rêgo K F , Sousa Luz J H , Becher G E 
Published: March 2024

Abstract

Introduction
Social media provides a favorable space for health education. Among the available digital resources, WhatsApp message groups can serve as a source of information and a platform for discussions. Recent studies on sexual education through social media are more concentrated on interventions targeting STI prevention, sexual abuse mitigation, and contraception education. However, there are no reports of utilization of WhatsApp for education about paraphilias. The Brazilian Association for Studies in Medicine and Sexual Health (ABEMSS) utilizes WhatsApp as a tool to promote discussions of this often neglected topic. Nevertheless, more studies are needed to substantiate the validity of this resource.

Objective
To review the literature and to share the experience of using WhatsApp to facilitate discussions and knowledge sharing about paraphilias.

Methods
Narrative Review on the Use of Social Media in Sexual Education and an experience report on the Utilization of WhatsApp as an Educational Instrument for the study of paraphilias.

Results
The WhatsApp paraphilia study group was created in 2020 and comprises 222 healthcare professionals (54% urologists, 9% endocrinologists, 8% psychiatrists, 18% psychologists, 7% physiotherapists). Its activities primarily occur in a scheduled manner, but they can also arise spontaneously. They include discussions of clinical cases, scientific studies and lay media. In the first half of 2023, there were 12 scheduled activities and 8 spontaneous ones. To mitigate the risk of stigmatizing comments, department members act as moderators.

Conclusions
WhatsApp seems to be a valuable tool for disseminating information about neglected health topics, such as paraphilias. The use of specific groups with scheduled and spontaneous activities promotes the provision of scientific information while promotes a attitude towards the topic.

Keywords
Paraphilias; Paraphilic disorders; Medical education; Social media

Financing
No conflict.
(PM-24) TRANSLATION AND CULTURAL ADAPTATION OF THE KAROLINSKA INTERPERSONAL VIOLENCE SCALE INTO BRAZILIAN PORTUGUESE: A METHODOLOGICAL STUDY
Authors: O  Ferreira B , W  Gil M L , Talib L , Jokinen J , T  Scanavino M 
Published: March 2024

Abstract

Introduction
Interpersonal violence is a global concern with significant implications for mental health and mortality. The Karolinska Institute in Sweden developed the Karolinska Interpersonal Violence Scale (KIVS), a semi-structured interview assessing interpersonal violence experiences as victims or aggressors across childhood and adulthood.

Objective
Our aim was to translate and culturally adapt the KIVS for use in the Brazilian population. Methods: The translation process involved ten stages based on The International Society for Pharmacoeconomics and Outcomes Research (ISPOR) guidelines. Back-translation was performed by a clinical psychologist unfamiliar with the original scale. The English versions were cross compared by the original instrument author. The consensus version underwent comprehension evaluation by eight participants, comprising four healthcare professionals and four patients from the AISEP - Excessive Sexual Drive and Prevention of Negative Outcomes Related with Sexual Behavior at Instituto de Psiquiatria of Hospital das Clínicas of São Paulo. A 5-point Likert scale assessed participant comprehension, with 80% agreement indicating successful equivalence. Sentences were revised until this consensus was achieved. The finalized translation, incorporating contextual revisions, underwent syntactic and spelling review.

Results
After application to eight participants (4 women and 4 men), 7 rated with the highest comprehension score (5.0), and 1 with 4.9. A final report documented the entire KIVS translation and validation process.

Conclusion
The translation and cultural adaptation of the KIVS into Brazilian Portuguese were successful. Minor adjustments were made to enhance comprehension without compromising meaning. This adaptation provides a valuable tool for assessing interpersonal violence in the Brazilian context, with implications for research and clinical practice.

Financing
FAPESP.
Health problems and exposure to infectious risks in returning humanitarian aid workers
Authors: Benabdelmoumen Ghania , Van der Pluijm Rob W , Taieb Fabien , Jidar Kaoutar , Kuhmel Lucie , Lucet Cora , Buffet Pierre , Hochedez Patrick , Itani Oula , Consigny Paul-Henri 
Published: March 2024

Abstract

Background
Humanitarian aid workers are exposed to deployment-related health threats. Identifying subgroups at a higher risk of infection in this diverse population could help optimize prevention.

Methods
We carried out a retrospective study based on anonymized data of humanitarian aid workers that visited our clinic for a post-deployment visit between 1 January 2018 and 31 December 2021. We conducted a descriptive analysis of basic demographic data, self-reported risk exposure and health problems encountered during deployment extracted from a standard questionnaire.

Results
The questionnaire was administered to 1238 aid workers during 1529 post-deployment medical consultations. The median age was 37.2 years (IQR 31.7–44.3), and 718/1529 (47.0%) were female aid workers. The median duration of deployment was 6 months (IQR 3–12 months). Most deployments (1321/1529 (86.4%)) were for a medical organization and in Sub-Saharan Africa (73.2%). The most common risk exposures were contact with freshwater in schistosomiasis endemic regions (187/1308 (14.3%)), unprotected sexual contact with a person other than a regular partner (138/1529 (9.0%)), suspected rabies exposure (56/1529 (3.7%)) and accidental exposure to blood (44/1529 (2.9%)). Gastrointestinal problems (487/1529 (31.9%)), malaria (237/1529 (15.5%)) and respiratory tract infections (94/1529 (6,2%)) were the most encountered health problems. Fifteen volunteers (1%) were hospitalized during deployment and 19 (1.2%) repatriated due to health problems. Adherence to malaria chemoprophylaxis was poor, only taken according to the prescription in 355 out of 1225 (29.0%) of aid workers for whom prophylaxis was indicated.

Conclusion
Humanitarian aid workers deployed abroad encounter significant rates of health problems and report a high level of risk exposure during their deployment, with the risks being greatest among younger people, those deployed to rural areas, and those working for non-medical organizations. These findings help guide future pre-deployment consultations, to increase awareness and reduce risk behaviour during deployment, as well as focus on adherence to medical advice such as malaria chemoprophylaxis.
Rapid Life-Saving Response to Anti–PD-1 in a Solid Organ Transplant Recipient With Metastatic Cutaneous Squamous Cell Carcinoma: A Case Report and Review
Authors: Antonelli John P. , Quach Myiah , Mahajan Aparna , Pleva Jennifer , Ma Vincent T. 
Published: March 2024

Summary
Anti–programmed cell death protein 1 (PD-1) therapy is considered effective in the treatment of metastatic or locally advanced cutaneous squamous cell carcinoma but the use of these agents in solid organ transplant recipients (SOTRs) is often taken with caution. While anti-tumor effects without graft rejection have been reported, studies have shown high rates of fatal graft rejection with immune checkpoint therapy. In this case report, we present an SOTR patient with life-threatening, acute hypoxic respiratory failure due to rapidly progressive metastatic cutaneous squamous cell carcinoma with lung and pleural involvement. Modification of their immunosuppressive regimen and treatment with front-line anti–PD-1 inhibitor, pembrolizumab, led to rapid clinical response with near complete resolution of metastatic pulmonary disease and no long-term evidence of graft rejection. Our case report shows that front-line treatment with PD-1 inhibitors can be safely administered in SOTR patients with rapid metastatic disease control.
Cardiometabolic Risk Profiles of Adolescents Living With Perinatally Acquired HIV in South Africa
Authors: Greybe Leonore , Barnabas Shaun , Cotton Mark , Rose Penelope , Rabie Helena , Frigati Lisa 
Published: March 2024

Background:
We assessed the Pathological Determinants of Atherosclerosis in Youth (PDAY) score and other potential cardiovascular disease risk factors in adolescents previously enrolled in the Children with HIV Early antiRetroviral (CHER) and International Maternal Pediatric Adolescent AIDS Clinical Trials Network P1060 clinical trials.

Methods:
Coronary artery and abdominal aorta (AA) PDAY scores were calculated for 56 participants over 15 years of age using a weighted combination of dyslipidemia, cigarette smoking, hypertension, obesity, and hyperglycemia. A PDAY score ≥1 is associated with early atherosclerosis.

Results:
Fifty-six participants were enrolled: 46 (82.1%) on a single-tablet regimen of tenofovir disoproxil fumarate, lamivudine and dolutegravir. Median time on antiretroviral therapy was 15.8 [interquartile range (IQR): 15.8–16.5] years and median time on dolutegravir was 14 (IQR: 10.0–19.0) months. Fasting median high-density lipoprotein cholesterol was 20.1 mg/dL (IQR: 16.0–23.7) and median non-high-density lipoprotein cholesterol was 38.3 mg/dL (IQR: 30.8–44.3). The median systolic blood pressure was 115 mm Hg (IQR: 107–121). Median body mass index was 21.3 kg/m2 (IQR: 19.5–24.7) and median fasted serum glucose was 82.0 mg/dL (IQR: 75.7–87.3). Only 1 (2%) participant smoked cigarettes, but 5 (9%) smoked hookah pipe and 26 (46.4%) smoked cannabis. Thirty-one (55.4%) participants had coronary artery PDAY scores ≥1 and 33 (58.9%) had AA PDAY scores ≥1. Age was associated with an AA PDAY score ≥1 (P = 0.02) with a 0.06 increase in AA PDAY score for every month of age (95% confidence interval: 0.01–0.12, P = 0.01).

Conclusions:
Adolescents with perinatally acquired HIV appear at risk for cardiovascular disease. Specific tools for monitoring this risk are needed to institute appropriate preventive interventions.
An update of palliative care in lung transplantation with a focus on symptoms, quality of life and functional outcomes
Authors: Rozenberg Dmitry , Andrawes Rogih Riad , Wentlandt Kirsten 
Published: March 2024

Purpose of review
Palliative care (PC) in lung transplantation is increasingly acknowledged for its important role in addressing symptoms, enhancing functionality, and facilitating advance care planning for patients, families, and caregivers. The present review provides an update in PC management in lung transplantation.

Recent findings
Research confirms the effectiveness of PC for patients with advanced lung disease who are undergoing transplantation, showing improvements in symptoms and reduced healthcare utilization. Assessment tools and patient-reported outcome measures for PC are commonly used in lung transplant candidates, revealing discrepancies between symptom severity and objective measures such as exercise capacity. The use of opioids to manage dyspnea and cough in the pretransplant period is deemed safe and does not heighten risks posttransplantation. However, the integration of PC support in managing symptoms and chronic allograft dysfunction in the posttransplant period has not been as well described.

Summary
Palliative care support should be provided in the pretransplant and select peri-operative and posttransplant periods to help support patient quality of life, symptoms, communication and daily function.
The Nature of Combat Stress Development During Military Operations and Psychotherapy in Extreme Situations
Authors: Ovsyannikova Yanina , Pokhilko Diana , Krasnokutskyi Mykola , Kerdyvar Valentyn , Kreshchuk Kateryna 
Published: March 2024

Abstract
The purpose of the research work is the theoretical and empirical analysis of the study of the nature of combat stress in military personnel and the assessment of psychotherapeutic methods of providing psychological assistance in extreme situations. The authors used the following methods to achieve this goal: method of analysis and synthesis, hermeneutic method, testing method, comparative method, and generalization method. The results of the research work have revealed the meaning of traumatic stress, psychological trauma, and combat mental trauma, and explained the concept of combat stress and the dynamics of its growth. The findings identified the factors of posttraumatic stress syndrome and its prevalence, tracked down the dynamics of psychoemotional disorders, and revealed the importance of military psychological selection and determination of combat readiness. The authors established the main tasks of a staff psychologist in working with military personnel, conducted an empirical study of the nature of combat stress in the military, observed main psychotherapeutic tools for the prevention of negative mental states in combat conditions, and investigated self-regulation techniques of emotional, physical, and mental health. The practical significance of the scientific work lies in the modern coverage of the phenomenon of combat stress and the classification of effective psychotherapeutic methods that will ensure the sustainable psychological preparation of the soldiers for extreme situations.
Evaluation of Laparoscopic Colorectal Resection Among Elderly Individuals With Colorectal Malignancy: A Single-center Retrospective Analysis
Authors: Zhang Yanru , Chen Tufeng , Yang Xiaofeng , Li Yiquan , Lei Purun 
Published: March 2024

Objective:
The purpose of the current study was to statistically clarify the precise risk age in elderly patients undergoing colorectal surgery and to evaluate the safety and efficacy of laparoscopic colorectal resection in these patients.

Methods:
Patients’ clinical variables were extracted from the database of the Gastrointestinal Surgery Centre, Third Affiliated Hospital of Sun Yat-sen University, from 2015 to 2019. Logistic regression was conducted to identify independent risk factors of postoperative complications and ORs for each age. Curves of odds ratios (ORs) and CIs for each age were fitted by using a locally weighted scatterplot smoother, and a structural breakpoint was determined by the Chow test to identify a precise cutoff risk age for elderly patients. Comparison and subgroup analysis were conducted between surgical approach groups using the Student t test and χ2 analysis.

Results:
Locally weighted scatterplot smoother OR analysis manifested that patients aged 69 years old or older suffered a higher possibility of postoperative complications and should be defined as high-risk age. Comparison according to the high-risk age revealed laparoscopic colorectal surgery is better than laparotomic surgery for elderly individuals in terms of hospital stay (9.46 ± 5.96 vs 15.01 ± 6.34, P < 0.05), the incidence of intensive care unit transfer (4 vs 20, P < 0.05), and incidence of surgical site infection (15 vs 20, P < 0.05). Patients who underwent laparotomic surgery had a greater prevalence of Clavien-Dindo II/III complications (P < 0.05). These findings remained stable even after propensity matching. Furthermore, such superiority was proved especially significant for patients who underwent left-side colorectal resection. In addition, overall survival was improved in the laparoscopic surgery group, whereas no differences were observed in disease-free survival.

Conclusion:
In our study population, age 69 or older was a cutoff point age suggests a higher possibility of postoperative morbidity after colorectal surgery. Laparoscopic colorectal resection should be regarded as a superior therapeutic choice for these elderly individuals, especially for left-side colorectal surgeries.
Factors influencing nurses’ use of sedation interruptions in a critical care unit: a descriptive qualitative study
Authors: Graham Nicole D. , Graham Ian D. , Vanderspank-Wright Brandi , Nadalin Penno Letitia , Fergusson Dean A. , Squires Janet E. 
Published: March 2024

ABSTRACT

Introduction and aims:
This study examined critical care nurses’, physicians’, and allied health professionals’ perceptions of factors that support, inhibit, or limit the use of sedation interruption (SI) to improve the use of this integral component of care for mechanically ventilated patients.

Method:
We conducted a theory-based, descriptive qualitative study using semi-structured interviews with critical care registered nurses, respiratory therapists, a pharmacist, and a physician in a hospital in Ontario, Canada. The interview guide and analysis were informed by the Theoretical Domains Framework and transcripts were analyzed using content analysis.

Results:
We identified 9 facilitators and 20 barriers to SI use by nurses. Facilitators included the innovation (importance of protocols) and potential adopters (comfort with the skill). The barriers were the potential adopters’ (nurses) knowledge gaps regarding the performance and goal of SI and the practice environment (lack of time, availability of extra staff, and lack of multidisciplinary rounds).

Conclusion:
This study identified facilitators and barriers to SI for mechanically ventilated patients. Implementation efforts must address barriers associated with nurses, the environment, and contextual factors. A team-based approach is essential, as the absence of interprofessional rounds is a significant barrier to the appropriate use or non-use of SI. Future research can focus on the indications, contraindications, and goals of SI, emphasizing a shared appreciation for these factors across disciplines. Nursing capacity to manage a patient waking up from sedation is necessary for point-of-care adherence; future research should focus on the best ways to do so. Implementation study designs should use theory and evidence-based determinants of SI to bridge the evidence-to-practice gap.

Spanish abstract:

http://links.lww.com/IJEBH/A178