bluuebunny/crossref_metadata_2025_split huggingface dataset:
Use of the Guardian Connect glycemic monitoring system in patients after total duodenopancreatectomy in the early postoperative period on intravenous insulin therapy
Authors: Farmanov A. G. , Bublik E. V. , Vinogradskaya O. I. , Udovichenko O. V. , Zilov A. V. , Deunezheva S. M. , Ryzhkova E. G. , Egorov V. I. , Fadeev V. V. , Zhivov A. V. , Tobianskaya I. E. 
Published: March 2024

BACKGROUND: Among different subtypes of pancreatogenic diabetes mellitus the biggest difficulties of glycemic control arise in patients after total duodenopancreatectomy (TDPE), first of all due to the presence of absolute insulin insufficiency.AIM: Estimating safety and cost-effectiveness Guardian Connect CGM system in early postoperative period in hospitalized patients after TDPE on continuous intravenous insulin therapy (CIVIT).MATERIALS AND METHODS: Glucose measurement results of 26 patients in early postoperative period after TDPE were analyzed. In 12 of them, we used Guardian Connect CGM system. In this group 43 cycles (1 cycle — 6 days, 258 days total) of CGM and 971 glucometer measurements used for CGM calibration were analyzed; in other 14 patients in whom only glucometer was used we analyzed 2496 glycemic values.Cost-effectiveness was calculated over 6 days for CGM and only glucometer use (including cost of CGM, glucometers, disposable materials, clinic wage-costs to medical staff for time required for glucose control).RESULTS: Glucose levels of group #1 were in the target range 5.6 to 10.0 mmol/L (66.7 vs 61.2%, p=0.003) and the range 4.3–11.6 mmol/L (85.2% vs 82.2%, p=0.038) more than in comparison with group #2.The frequency of hypoglycemic episodes (<3.9 mmol/L) was statistically significantly lower in the CGM group (6 vs 54, p<0.001, RO 8.463 [3.579; 20.015], RR 1.746 [1.551; 1.966]).Cost analysis of glucose control using Guardian Connect CGM system for one cycle (6 days) and cost of glucose control using glucose meter for the same period showed that using Guardian Connect CGM system in patients after TDPE on intravenous insulin therapy reduced clinic costs by 21.7% in ICU and by 25.7% in the hospital department.CONCLUSION: Guardian Connect CGM have demonstrated its safety and cost-effectiveness during glucose control in patients in early postoperative period after TDPE on CIVIT.
Grenzüberschreitende Zentrale Orte im bayerisch-tschechischen Grenzgebiet – ein Lückenschluss für die Daseinsvorsorge?
Authors: Bloßfeldt Stefan 
Published: March 2024

Creating equal living conditions in rural border regions poses a particular challenge for policy-makers and planners. In addition to demographic factors, national borders negatively affect the sustainability of services of general interest. However, overcoming border-related barriers also holds potential to compensate for gaps in service provision. It is therefore noteworthy that Bavarian federal state planning has designated so-called cross-border central places (GRZO) since 1994. Since the instrument is not legally binding abroad, its effectiveness appears to be limited. Moreover, it is unclear to what extent cross-border public services on the basis of cross-border central places are perceived as a potential by the population concerned. In order to discuss this, guided interviews were conducted with citizens in affected Bavarian municipalities on the Czech border and complemented by expert interviews. On the one hand, the results indicate a limited perception of cross-border public services as a relevant potential. On the other hand, they point to some concrete expectations of the cross-border central places designation that have not yet been fulfilled and at times reinforce a latent feeling of being left behind.
Modulation of potassium channels by transmembrane auxiliary subunits via voltage‐sensing domains
Authors: Nakajo Koichi , Kasuya Go 
Published: March 2024

AbstractVoltage‐gated K+ (KV) and Ca2+‐activated K+ (KCa) channels are essential proteins for membrane repolarization in excitable cells. They also play important physiological roles in non‐excitable cells. Their diverse physiological functions are in part the result of their auxiliary subunits. Auxiliary subunits can alter the expression level, voltage dependence, activation/deactivation kinetics, and inactivation properties of the bound channel. KV and KCa channels are activated by membrane depolarization through the voltage‐sensing domain (VSD), so modulation of KV and KCa channels through the VSD is reasonable. Recent cryo‐EM structures of the KV or KCa channel complex with auxiliary subunits are shedding light on how these subunits bind to and modulate the VSD. In this review, we will discuss four examples of auxiliary subunits that bind directly to the VSD of KV or KCa channels: KCNQ1–KCNE3, Kv4‐DPP6, Slo1‐β4, and Slo1‐γ1. Interestingly, their binding sites are all different. We also present some examples of how functionally critical binding sites can be determined by introducing mutations. These structure‐guided approaches would be effective in understanding how VSD‐bound auxiliary subunits modulate ion channels.
Synthesis, characterization and evaluation of a pH-responsive molecular imprinted polymer for Matrine as an intelligent drug delivery system
Authors: Ge Yanhui , Ding Liuyang , Liu Yubo , Li Xiong 
Published: March 2024

Abstract
To address the undesirable reactions associated with matrine (MAT) injection in clinical settings, a high-loading drug delivery system (DDS) based on pH-sensitive molecularly imprinted polymer (MAT@MIPs) was prepared for the first time. The imprinted materials containing recognition sites for the matrine were formed by using carboxyl-functionalized multiwalled carbon nanotubes as a supportive matrix and dopamine as a cross-linker due to its exceptional biocompatibility. Subsequently, the optimal reaction conditions and adsorption performance of MAT@MIPs were systematically investigated. The obtained polymers were characterized and evaluated by Fourier transform infrared spectrometry, scanning electron microscopy, elemental analysis, and thermogravimetric analysis. Results indicated that the MIPs demonstrated a favorable imprinting factor (2.36) and a high binding capacity (21.48 mg·g−1) for matrine. In vitro studies, we performed cell counting kit-8 assays in HepG2 cells, then the drug delivery capabilities of MAT-loaded MIPs were validated through light microscopy analyses, and the matrine content in culture medium was quantified using ultra high-performance liquid chromatography-mass spectrum synchronously. The facile fabrication of MAT@MIPs presents a viable solution for designing high-loading and pH-responsive DDS, which can offer a novel administration approach for drugs requiring injection in clinical applications.
Learning academic vocabulary through reading online news
Authors: Dang Thi Ngoc Yen , Lu Cailing 
Published: March 2024

Abstract
Although corpus-driven studies have suggested that non-academic texts such as online news can be a potential resource for learning specialized words and multiword sequences, no intervention studies have been conducted to examine whether learning actually happens from exposure to these texts. Adopting a quasi-experimental design, the present research investigated the potential of online news for incidentally learning academic words and multiword sequences. Fifty-three university students in China were divided into an experimental group (n = 28) or a control group (n = 25). Students in the experimental group read six pieces of online news containing 16 academic words and 26 academic multiword sequences. Students in the control group were not exposed to such online news. This study showed that reading online news resulted in learning gains of both academic single words and multiword sequences. Frequency of occurrence significantly contributed to the learning outcomes of academic words, but not multiword sequences. Learners’ previous vocabulary knowledge did not play a significant role in explaining the learning gains of academic single words nor multiword sequences.
A Q methodological study into pre-service Chinese as a foreign language (CFL) teachers’ mindsets about teaching competencies
Authors: Yuan Chengwen , Zhu Yong , Slaughter Yvette 
Published: March 2024

Abstract
A teacher’s mindset significantly affects their engagement, development, teaching quality, and well-being. This is crucial for pre-service teachers acquiring competencies for effective teaching. While research often focuses on English language teaching in Western contexts, little explores non-Western language teaching mindsets. Given the intersections of associated social, cultural, and linguistic variables with mindset, this study investigates Chinese as a foreign language (CFL) pre-service teachers’ mindsets on teaching competencies. The study utilized Q methodology, which is a philosophical and conceptual framework for examining subjectivity, and post-sort questionnaires with 39 pre-service teachers in China. The research findings provide important insights into the diverse and contradictory mindsets of pre-service CFL teachers, and the ideologies influencing beliefs as to what constitutes effective language teaching in the Chinese socio-cultural and socio-political context, providing insights into how teacher training programs need to be tailored to challenge and extend the complex mindsets held by pre-service language teachers.
Hybrid effect on tensile, flexural, and quasi-static punch shear behavior of jute/ramie and jute/flax reinforced hybrid composites
Authors: Keleş Özlem , Bati Serkan , Çelik Yahya Hışman 
Published: March 2024

Abstract
The high specific properties and environmental durability of synthetic fibers make them a popular choice for reinforcing lightweight composites. Unfortunately, they are often limited by their poor biodegradability and high cost. Nevertheless, natural fibers are critical in industrial applications due to their environmental and economic benefits. This study investigated the tensile and flexural behavior of natural hybrid jute/ramie and jute/flax composites with different stacking sequences. A quasi-static punch shear test was also performed to understand their deformation behavior. Jute, ramie, and flax composites have also been fabricated for comparison. Tensile and flexural tests showed a positive hybrid effect in some samples, whereas flax–jute hybrid composites in two different stacking sequences exhibited a synergistic effect. While a maximum improvement of 37.99 % was achieved in the tensile test, this rate was 64.81 % in the flexural test with these hybrid composites. According to punch shear experiments, punch geometry and stacking sequence considerably impact punch shear strength, energy absorption capacity, and deformation.
Effect of the heat treatment on the microstructure of carbide tool electrodes for electrical discharge drilling
Authors: Camin B. , Dinh C. , Streckenbach J. , Gille M. , Uhlmann E. 
Published: March 2024

Abstract
Carbide tool electrodes for electrical discharge drilling were subjected to heat treatment at various temperatures and in different atmospheres for the same duration, respectively, in order to reduce the electrical conductivity of the lateral surface. Hardness tests show that the heat treatment does not induce a loss of strength in the electrode body. Microscopic analyses revealed that the lateral surface, characterized by a two-layer structure comprising a surface and a diffusion layer of varying characteristics and morphology, such as surface roughness, degree of coverage, delaminations, or a columnar microstructure, changes. It is revealed that the electrical conductivity is a function of the total layer thickness made up of the thickness of the surface layer and a diffusion layer. The electrical conductivity drops with increasing total layer thickness. In the context of electric discharge drilling tests, it was found that the reduced electrical conductivity leads to a decreased material removal rate and a simultaneously reduced linear electrode wear. Heat treatments ensuring consistent erosion times resulted in a wear rate reduction of the tool electrodes of up to 10 %.
Seasonally flooded Coquinal: typifying a particular plant association in the northern Yucatan peninsula, Mexico
Authors: Duno de Stefano Rodrigo , Aguilar-Canché Mayte , Carnevali Fernández-Concha Germán , Ramírez-Morillo Ivón , Tapia-Muñoz José Luis , Reyes-Palomeque Gabriela , Angulo Diego F. 
Published: March 2024

Background: One of the most diverse and threatened plant associations in the Yucatan peninsula has not been characterized and therefore not included in any protection category in Mexico. We characterize and describe this plant association, which is rapidly disappearing or being irreversibly transformed as a result of anthropic activities. We propose a name and attempt a preliminary assessment of its taxonomic richness, and the identification of priority species to be preserved.
Questions: What is the species richness and plant endemism associated within this plant association? What are the ecologically important and high-priority species for conservation? How is it different from associated or similar plant associations?
Studied species: Vascular plants.
Study site and dates: Northern Yucatan peninsula; 2021-2023.
Methods: The plant association was characterized, and quantitative parameters were recorded. The Importance Value Index was estimated to assess its local ecological importance, and each species was assigned a conservation category in order to evaluate the conservation status in a global context.
Results: We propose Seasonally flooded Coquinal (SFC) as a name for this plant association based on geomorphological, physiognomic, and structural attributes. A total of 206 species were recorded, which two are endemic to the SFC and 28 to the Yucatan Peninsula Biotic Province (YPBP). Twelve species are listed under a risk category.
Conclusions: The SFC harbors a high plant diversity of endemic species to the YPBP, 12 of which are included in the IUCN red list, for which its typification and conservation should be a high priority in Mexico.
Heated Tobacco Products Have Detrimental Effects on Rotator Cuff Healing, Similar to Conventional Cigarettes
Authors: Yoon Tae-Hwan , Choi Jee-Hoon , Lim Joon-Ryul , Chang Hsien-Hao , Chun Yong-Min 
Published: March 2024

Background:
Cigarette smoking impairs rotator cuff healing, but no study, to our knowledge, has focused on the association between heated tobacco products and rotator cuff tears.

Methods:
This study retrospectively investigated 1,133 patients who underwent arthroscopic repair of symptomatic rotator cuff tears between March 2011 and April 2021. Patients were grouped on the basis of their smoking patterns as nonsmokers, cigarette smokers, and heated tobacco smokers. Propensity score matching was used to reduce selection bias, and 45 subjects were selected from each group via 1:1:1 matching. Functional scores and active range of motion were compared among the 3 groups preoperatively and at a 2-year follow-up. Postoperative magnetic resonance imaging was performed 6 months after the surgical procedure to assess structural integrity.

Results:
Except for sex, similar baseline characteristics were achieved after propensity score matching. There were no differences in the clinical scores or range of motion between the matched groups either preoperatively or at the 2-year follow-up. However, the retear rate for the matched nonsmoker group was significantly lower (8.9%) than those for the matched cigarette smoker group (31.1%) and the heated tobacco smoker group (28.9%) (p = 0.022). Multivariable logistic regression analysis revealed that the retear rates were 3.403 times higher for the cigarette smoker group and 3.397 times higher for the heated tobacco smoker group than that for the nonsmoker group.

Conclusions:
Heated tobacco users, like conventional cigarette smokers, have worse clinical outcomes with respect to rotator cuff healing than nonsmokers. Regardless of the type of cigarette, abstinence from smoking is necessary for patients undergoing rotator cuff repair surgery.

Level of Evidence:
Prognostic Level III. See Instructions for Authors for a complete description of levels of evidence.
P-702 Centrifugal Pump Damage Analysis Insights and Implications
Authors: Abdullah Barafi Keigen , Fahruddin A’rasy 
Published: March 2024

Centrifugal pumps are widely used in industries for fluid transfer, operating on the rotation of an impeller driven by a prime mover. However, sudden performance drops and operational instability pose significant challenges, impacting overall system efficiency. Predictive maintenance relies on vibration analysis to assess rotating equipment condition, with vibration patterns indicating potential issues such as cavitation and corrosion. Prolonged cavitation leads to erosion of channel wall surfaces, resulting in structural damage. This study aims to address the knowledge gap in understanding the relationship between pump vibration, cavitation, and corrosion. Through comprehensive vibration analysis and examination of pump performance, our research identifies the mechanisms driving pump degradation. The findings highlight the critical role of predictive maintenance in mitigating pump failures and optimizing system performance.
Highlights :

Vibration analysis crucial for predictive maintenance: Identifying early signs of pump deterioration.
Cavitation-induced erosion: Understanding the impact of prolonged cavitation on pump performance.
Importance of proactive maintenance: Mitigating pump failures and optimizing system efficiency.

Keywords : Centrifugal pumps, Vibration analysis, Cavitation, Corrosion, Predictive maintenance
Algorithm for Surface Wave Suppression on 2D Seismic Data Using the Slant Karhunen–Loeve Transform in a Time-Frequency Domain
Authors: Yablokov A.V. , Moiseev M.V. , Serdyukov A.S. , Litvichenko D.A. 
Published: March 2024

Abstract
—Surface waves are the main source of coherent noise in land seismic survey, and their suppression is one of the main stages of common depth point data processing designed to improve the quality of tracking primary reflections on time sections. In practice, noise reduction is carried out using procedures from modern software based on numerical modeling of waveforms. However, they are too resource-intensive and have a large number of subjectively customizable parameters. The known algorithms have a common drawback: either the energy of reflected waves is distorted in an interference zone with a noise wave or the noise suppression quality is unsatisfactory. The current research is aimed at improving the filtering algorithm in a time-frequency domain using the slant Karhunen–Loeve transform in order to overcome these limitations, to increase the accuracy and rate of its software implementation, and also to test it when processing profile field data from land-based 2D seismic surveys. The algorithm is modified by developing a new method for determining static corrections for surface wave hodograph rectification in a time-frequency domain and by the application of preprocessing in which the reflected wave signal is removed preliminarily. These and other modifications ensure faster calculations and improve the quality of surface wave interference suppression. In addition, the slant Karhunen–Loeve transform is accelerated by parallelizing calculations across logical processor cores. In this paper, the algorithm is described in detail, its significant advantage over the standard methods of bandpass filtering and F–K filtering is shown, and the results of processing the field data obtained by the SWANA procedure (Geovation 2.0) and by the slant Karhunen–Loeve transform. The result obtained by the slant Karhunen–Loeve transform is superior to the SWANA procedure in terms of the surface wave filtering quality and has only four adjustable parameters (SWANA has 20 parameters)
Fuzzy Logic-Based Landslide Susceptibility Mapping in Earthquake-Prone Areas: A Case Study of the Mila Basin, Algeria
Authors: Chettah W. , Mezhoud S. , Baadeche M. , Hadji R. 
Published: March 2024

Abstract
—This research focuses on analyzing landslides triggered by a moderate earthquake (Mw = 4.9) in the northeastern region of the Mila province, which resulted in significant damage and economic losses in the El Kherba district and Grarem Gouga city. Through an extensive field-based investigation, a comprehensive inventory of landslides has been compiled. To assess the susceptibility to landslides triggered by seismic activity, a GIS-based fuzzy logic model was employed. The model incorporates various input factors, such as lithology, slope angle, normalized difference vegetation index (NDVI), distance from rivers and roads, precipitation, and seismic hazard, which is shown on a map. The study compares the performance of different fuzzy operators and gamma values and determines that using fuzzy gamma operators with a gamma value of 0.8 yields a satisfactory consistency with the distribution of landslides. Moreover, incorporating the map of seismic hazard as a causative factor enhances the accuracy of landslide susceptibility mapping. This study underscores the utility of the fuzzy logic model in disaster management and the planning of development activities.
Glycan-shielded homodimer structure and dynamical features of the canine distemper virus hemagglutinin relevant for viral entry and efficient vaccination
Authors: Fukuhara Hideo , Yumoto Kohei , Sako Miyuki , Kajikawa Mizuho , Ose Toyoyuki , Kawamura Mihiro , Yoda Mei , Chen Surui , Ito Yuri , Takeda Shin , Mwaba Mwila , Wang Jiaqi , Hashiguchi Takao , Kamishikiryo Jun , Maita Nobuo , Kitatsuji Chihiro , Takeda Makoto , Kuroki Kimiko , Maenaka Katsumi 
Published: March 2024

Abstract

Canine distemper virus (CDV) belongs to morbillivirus, including measles virus (MeV) and rinderpest virus, which causes serious immunological and neurological disorders in carnivores, including dogs and rhesus monkeys, as recently reported, but their vaccines are highly effective. The attachment glycoprotein hemagglutinin (CDV-H) at the CDV surface utilizes signaling lymphocyte activation molecule (SLAM) and Nectin-4 (also called poliovirus-receptor-like-4; PVRL4) as entry receptors. Although fusion models have been proposed, the molecular mechanism of morbillivirus fusion entry is poorly understood. Here, we determined the crystal structure of the globular head domain of CDV-H vaccine strain at 3.2 Å resolution, revealing that CDV-H exhibits a highly tilted homodimeric form with a six-bladed β-propeller fold. While the predicted Nectin-4 binding site is well-conserved with that of MeV-H, that of SLAM is similar but partially different, which is expected to contribute to host specificity. Five N-linked sugars covered a broad area of the CDV-H surface to expose receptor binding sites only, supporting the effective production of neutralizing antibodies. These features are common to MeV-H, although the glycosylation sites are completely different. Furthermore, real-time observation using high-speed atomic force microscopy revealed highly mobile features of the CDV-H dimeric head via the connector region. These results suggest that sugar-shielded tilted-homodimeric structure and dynamic conformational changes are common characteristics of morbilliviruses and ensure effective fusion entry and vaccination.