bluuebunny/crossref_metadata_2025_split huggingface dataset:
Reaction of Dimethoxycarbene—DMAD Zwitterion with 1,2‐Diones and Anhydrides: A Novel Synthesis of Highly Substituted Dihydrofurans and Spirodihydrofurans.
Authors: Nair Vijay , Deepthi Ani , Poonoth Manojkumar , Santhamma Bindu , Vellalath Sreekumar , Babu Beneesh Pattoorpady , Mohan Resmi , Suresh Eringathodi 
Published: July 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Synthesis of Cyclic Dienamide Using Ruthenium‐Catalyzed Ring‐Closing Metathesis of Ene—Ynamide.
Authors: Mori Miwako , Wakamatsu Hideaki , Saito Nozomi , Sato Yukako , Narita Rie , Sato Yoshihiro , Fujita Reiko 
Published: July 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Highly Diastereoselective One‐Pot Synthesis of Spirocyclic Oxindoles Through Intramolecular Ullmann Coupling and Claisen Rearrangement.
Authors: Miyamoto Hiroshi , Okawa Yoichiro , Nakazaki Atsuo , Kobayashi Susumu 
Published: July 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Synthesis of 3‐(Arylmethylene)isoindolin‐1‐ones from Ynamides by Heck—Suzuki—Miyaura Domino Reactions. Application to the Synthesis of Lennoxamine.
Authors: Couty Sylvain , Liegault Benoit , Meyer Christophe , Cossy Janine 
Published: July 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Synthesis and Antioxidant Activity of New Tetrahydronaphthalene‐Indole Derivatives as Retinoid and Melatonin Analogues.
Authors: Ates‐Alagoz Zeynep , Coban Tulay , Buyukbingol Erdem 
Published: July 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Highly Efficient Construction of Benzene Ring in Carbazoles by Palladium‐Catalyzed endo‐Mode Oxidative Cyclization of 3‐(3′‐Alkenyl)indoles.
Authors: Kong Aidi , Han Xiuling , Lu Xiyan 
Published: July 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Synthesis of 3‐Substituted Ethyl Esters of 6‐Aryl‐5‐cyano‐2,4‐dioxo‐3‐azabicyclo[3.1.0]hexane‐1‐carboxylic Acid, Based on a Modified Reformatsky Reaction.
Authors: Shchepin V. V. , Silaychev P. S. 
Published: July 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Convenient Preparation of Substituted 5‐Aminooxazoles via a Microwave‐Assisted Cornforth Rearrangement.
Authors: Nolt M. Brad , Smiley Mark A. , Varga Sandor L. , McClain Ray T. , Wolkenberg Scott E. , Lindsley Craig W. 
Published: July 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Catalytic Activity of 1,3‐Dibromo‐5,5‐dimethylhydantoin (DBH) in the One‐Pot Transformation of N‐Arylglycines to N‐Arylsydnones in the Presence of NaNO2/Ac2O under Neutral Conditions: Subsequent Bromination of these Sydnones to Their 4‐Bromo Derivatives.
Authors: Azarifar Davood , Ghasemnejad‐Bosra Hassan 
Published: July 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
A Lewis Base‐Catalyzed Hetero Diels—Alder Reaction Between Aldehydes and the Danishefsky′s Diene.
Authors: Mukaiyama Teruaki , Kitazawa Takayuki , Fujisawa Hidehiko 
Published: July 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Catalytic Enantioselective Three‐Component Hetero‐[4 + 2] Cycloaddition/Allylboration Approach to α‐Hydroxyalkyl Pyrans: Scope, Limitations, and Mechanistic Proposal.
Authors: Gao Xuri , Hall Dennis G. , Deligny Michael , Favre Annaick , Carreaux Francois , Carboni Bertrand 
Published: July 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
4‐Aryl‐ and 4‐Vinyl‐2,2‐dialkyl‐3‐chromenes from Tertiary 3‐(o‐Bromophenyl)propynols via a Palladium‐Catalyzed Hydroarylation/Hydrovinylation—Cyclization Sequence.
Authors: Arcadi Antonio , Cacchi Sandro , Fabrizi Giancarlo , Marinelli Fabio , Verdecchia Mirella 
Published: July 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
3‐(4‐Phenyl‐1,2,4‐triazol‐3‐yl)chromones.
Authors: Shokol T. V. , Turov V. A. , Turov A. V. , Krivokhizha N. V. , Semenyuchenko V. V. , Khilya V. P. 
Published: July 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Copper‐Catalyzed Cyclopropanation of 1,2,3,4‐Tetrahydropyridin‐2‐ones with Trimethylsilyldiazomethane: A Facile and Selective Synthesis of 2‐Aza‐3‐oxobicyclo[4.1.0]heptanes.
Authors: Sharma Vishal B. , Jain Suman L. , Sain Bir 
Published: July 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Formation of Bispyridyl Derivatives During the Kost—Sagitullin Rearrangement.
Authors: Danagulyan G. G. , Tadevosyan D. A. 
Published: July 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
An Unexpected Palladium‐Catalyzed Cyclization of Bis‐Hydroxy Allylic Alcohols to Dioxabicylo[2.2.2]octanes.
Authors: Zawisza Anna , Sinou Denis 
Published: July 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
One‐Pot Synthesis of 3,4‐Dihydropyrimidin‐2(1H)‐ones Using Hydrochloric Acid‐β‐cyclodextrin‐Combined Catalysts.
Authors: Zhou Haixia , He Miao , Liu Chunsheng , Luo Genxiang 
Published: July 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Synthesis of Novel 3‐(Alkylcarbamoyl)‐2‐aryl‐1,2‐dihydro‐6,7‐ (methylenedioxy)‐3H‐quinazolin‐4‐ones as Anticonvulsant Agents.
Authors: Micale Nicola , Postorino Giovanna , Grasso Silvana , Zappala Maria , Zuccala Giuseppe , Ferreri Guido , De Sarro Giovambattista 
Published: July 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Regio‐ and Stereoselective Methoxyselenenylation of Chiral 2‐Vinyl Perhydro‐1,3‐benzoxazines Promoted by Selenium‐Heteroatom Nonbonded Interactions.
Authors: Pedrosa Rafael , Andres Celia , Arias Raquel , Mendiguchia Pilar , Nieto Javier 
Published: July 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Identification of Cytotoxic, T‐Cell‐Selective 1,4‐Benzodiazepine‐2,5‐diones.
Authors: Francis Tasha M. , Sundberg Thomas B. , Cleary Joanne , Groendyke Todd , Opipari Anthony W. Jr. , Glick Gary D. 
Published: July 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Aminomethylation of 1,2,3,4‐Tetrahydropyridine‐6‐thiolates: A Novel Approach to Synthesis of 3,7‐Diazabicyclo[3.3.1]nonane Derivatives.
Authors: Dotsenko V. V. , Krivokolysko S. G. , Litvinov V. P. 
Published: July 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Carbonyl‐Containing Spirodihydrofurans in Reactions with Ammonium Acetate and Hydrazine Hydrate.
Authors: Fedotova O. V. , Skuratova M. I. , Reshetov P. V. , Panov M. A. 
Published: July 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Studies on Tellurium‐Containing Heterocycles. Part 25. 1‐Allylation of 2‐Benzotelluropyrylium Salts and 2‐Benzoselenopyrylium Salts by Means of Allyltin Reagents.
Authors: Ohyanagi Kazuo , Sashida Haruki 
Published: July 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Taxoid from the Needles of the Himalayan Yew Taxus wallichiana with Cytotoxic and Immunomodulatory Activities.
Authors: Chattopadhyay Sunil K. , Pal Anirban , Maulik Prakas R. , Kaur Tanpreet , Garg Ankur , Khanuja Suman Preet S. 
Published: July 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Jaspolides A—F, Six New Isomalabricane‐Type Terpenoids from the Sponge Jaspis sp.
Authors: Tang Shengan , Pei Yuehu , Fu Hongzheng , Deng Zhiwei , Li Jun , Proksch Peter , Lin Wenhan 
Published: July 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Nebularic Acids and Nebularilactones, Novel Drimane Sesquiterpenoids from the Fungus Lepista nebularis.
Authors: Wangun Hilaire V. Kemami , Doerfelt Heinrich , Hertweck Christian 
Published: July 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Two New C19‐Diterpenoid Alkaloids from Aconitum hemsleyanium var. circinacum.
Authors: Gao Feng , Chen Dong‐Lin , Wang Feng‐Peng 
Published: July 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Afzeliixanthones A and B, Two New Prenylated Xanthones from Garcinia afzelii Engl. (Guttiferae).
Authors: Kamdem Waffo Alain Francois , Mulholland Dulcie , Wansi Jean Duplex , Mbaze Luc Meva'a , Powo Robert , Mpondo Theophile Ngando , Fomum Zacharias Tanee , Koenig Wilfried , Nkengfack Augustin Ephrem. 
Published: July 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Synthesis and Antitumor Evaluation of Symmetrical 1,5‐Diamidoanthraquinone Derivatives as Compared to Their Disubstituted Homologues.
Authors: Huang Hsu‐Shan , Chiu Hui‐Fen , Tao Chi‐Wei , Chen In‐Been 
Published: July 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Three New Lignans, Longipedunins A—C, from Kadsura longipedunculata and Their Inhibitory Activity Against HIV‐1 Protease.
Authors: Sun Quan‐Zhong , Chen Dao‐Feng , Ding Pei‐Lan , Ma Chao‐Mei , Kakuda Hiroko , Nakamura Norio , Hattori Masao 
Published: July 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Theoretical Modeling of Zeolite Catalysis: Nitrogen Oxide Catalysis over Metal‐Exchanged Zeolites
Authors: McMillan Scott A. , Broadbelt Linda J. , Snurr Randall Q. 
Published: July 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
The Cycloaddition Strategy for the Synthesis of Natural Products Containing Carbocyclic Seven‐Membered Rings
Authors: Battiste Merle A. , Pelphrey Phillip M. , Wright Dennis L. 
Published: July 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Acyl Anion Synthons: Benzotriazole Stabilized Compared to Classical
Authors: Katritzky Alan R. , Kirichenko Kostyantyn 
Published: July 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
A New Aspect of Fluoroalkylated Acetylenes: Synthesis and Applications — Hydrometalation and Carbometalation
Authors: Konno Tsutomu , Ishihara Takashi 
Published: July 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
The Reductive Decyanation Reaction: Chemical Methods and Synthetic Applications
Authors: Mattalia Jean‐Marc , Marchi‐Delapierre Caroline , Hazimeh Hassan , Chanon Michel 
Published: July 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Phosphodiesterase 5 (PDE5) Inhibitors for the Treatment of Male Erectile Disorder: Attaining Selectivity versus PDE6
Authors: Pissarnitski Dmitri 
Published: July 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Capabilities, Limitations and Challenges of a Simplified PC‐SAFT Equation of State
Authors: von Solms Nicolas , Kouskoumvekaki Irene A. , Michelsen Michael L. , Kontogeorgis Georgios M. 
Published: July 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Iron Corrolates: Unambiguous Chloroiron(III) (Corrolate)2‐ π‐Cation Radicals
Authors: Walker F. Ann , Licoccia Silvia , Paolesse Roberto 
Published: July 2006

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Sudden blast crisis in patients with Philadelphia chromosome‐positive chronic myeloid leukemia who achieved complete cytogenetic remission after imatinib therapy
Authors: Alimena Giuliana , Breccia Massimo , Latagliata Roberto , Carmosino Ida , Russo Eleonora , Biondo Francesca , Diverio Daniela , Mancini Marco , Nanni Mauro , Mandelli Franco 
Published: July 2006

AbstractBACKGROUND.Most patients with Philadelphia chromosome (Ph)‐positive chronic myeloid leukemia (CML) in chronic phase (CP) who receive treatment with imatinib achieve complete cytogenetic remission (CCR), which is correlated tightly with long‐term progression‐free survival. In these patients, the occurrence of blastic crisis (BC) is rare, and its clinical biologic characteristics are not well known.METHODS.Among 164 patients who received imatinib and were followed for a median of 35 months, 11 patients (6.7%) developed a BC; this was sudden (i.e., it occurred within 3 months of a documented CCR) in 6 patients (54.5%). Those patients were analyzed with respect to their clinical and biologic features and were compared with previous reports.RESULTS.At the time of diagnosis, there were 3 low‐risk patients and 3 intermediate‐risk patients; 4 patients had received pretreatment with interferon, and 2 patients received only imatinib. The median CP was 18 months, and the median duration of imatinib therapy was 7 months. The median time to CCR was 3 months, and the median time from CCR to BC was 4 months. BC phenotype was lymphoid in 2 patients, myeloid in 3 patients (including 2 patients who had extramedullary localization), and biclonal in 1 patient. Karyotype evolution was detected in 4 patients, whereas a Ph‐positive/Ph‐negative mosaicism was evident in all 6 patients. One patient presented an M351T mutation. The overall median survival was 3 months.CONCLUSIONS.Sudden BC generally is an uncommon phenomenon that may be relatively frequent in patients with CML who receive imatinib. Clinical and biologic features also seem to characterize this peculiar type of abrupt disease evolution, which intervenes in patients' response to this drug. Close monitoring of disease markers and full disease eradication are warranted. Cancer 2006. © 2006 American Cancer Society.
Proton Mobility in 2‐Substituted 1,3‐Dichlorobenzenes: “ortho” or “meta” Metalation?
Authors: Schlosser Manfred , Heiss Christophe , Marzi Elena , Scopelliti Rosario 
Published: July 2006

AbstractNine 1,3‐dichlorobenzene congeners were selected as model compounds to assess the relative rates of proton abstraction from 4‐ and 5‐positions (“ortho” vs. “meta” metalation). Using lithium 2,2,6,6‐tetramethylpiperidide as the basic reagent, the chlorine‐adjacent 4‐position underwent metalation exclusively. In contrast, attack at the chlorine‐remote 5‐position became significant even in the case of moderately sized 2‐substituents (such as dimethylamino or ethyl) when sec‐butyllithium was employed. The “ortho/para” (4‐/5‐) ratios ranged from 80:20 to 65:35. The more pronounced “meta‐orienting” effect of silicon as opposed to carbon substituents can be attributed to dissimilarities in the π polarization of the aromatic ring.(© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2006)
Effects of ginger (Zingiber officinale Roscoe) on DNA damage and development of urothelial tumors in a mouse bladder carcinogenesis model
Authors: Bidinotto Lucas Tadeu , Spinardi‐Barbisan Ana Lúcia Tozzi , Rocha Noeme Sousa , Salvadori Daisy Maria Fávero , Barbisan Luís Fernando 
Published: July 2006

AbstractExtracts of the spice ginger (Zingiber officinale Roscoe) are rich in gingerols and shogaols, which exhibit antioxidant, anti‐inflammatory, antifungal, antimycobacterial, and anticarcinogenic proprieties. The present study evaluated the chemoprotective effects of a ginger extract on the DNA damage and the development of bladder cancer induced by N‐butyl‐N‐(4‐hydroxibutyl) nitrosamine (BBN)/N‐methyl‐N‐nitrosourea (MNU) in male Swiss mice. Groups G1–G3 were given 0.05% BBN in drinking water for 18 weeks and four i.p. injections of 30 mg/kg body weight MNU at 1, 3, 10, and 18 weeks. Group G4 and G5 received only the BBN or MNU treatments, respectively, and groups G6 and G7 were not treated with BBN or MNU. Additionally, Groups G2, G3, and G6 were fed diets containing 1, 2, and 2% ginger extract, respectively, while Groups G1, G4, G5, and G7 were fed basal diet. Samples of peripheral blood were collected during the experiment for genotoxicity analysis; blood collected 4 hr after each MNU dose was used for the analysis of DNA damage with the Comet assay (assay performed on leukocytes from all groups), while reticulocytes collected 24 hr after the last MNU treatment of Groups G5–G7 were used for the micronucleus assay. At the end of the experiment, the urinary bladder was removed, fixed, and prepared for histopathological, cell proliferation, and apoptosis evaluations. Ginger by itself was not genotoxic, and it did not alter the DNA damage levels induced by the BBN/MNU treatment during the course of the exposure. The incidence and multiplicity of simple and nodular hyperplasia and transitional cell carcinoma (TCC) were increased by the BBN/MNU treatment, but dietary ginger had no significant effect on these responses. However, in Group G2 (BBN/MNU/2% ginger‐treated group), there was an increased incidence of Grade 2 TCC. The results suggest that ginger extract does not inhibit the development of BBN‐induced mouse bladder tumors. Environ. Mol. Mutagen., 2006. © 2006 Wiley‐Liss, Inc.
Functional analysis of gammaretroviral vector transduction by quantitative PCR
Authors: Meza N. W. , Puyet A. , Pérez‐Benavente S. , Quintana‐Bustamante O. , Diez A. , Bueren J. A. , Segovia J. C. , Bautista J. M. 
Published: July 2006

AbstractBackgroundIn a clinical setting of gene therapy, quantitative methods are required to determine recombinant viral titres and transgene mRNA expression, avoiding the use of reporter genes.MethodsWe describe procedures based on quantitative polymerase chain reaction (qPCR) designed to assess functional titres of murine leukaemia virus (MLV) vectors, determine proviral copy numbers in transduced cells, and estimate retroviral transgene expression in both target cell lines and mice with transduced chimeric haematopoiesis.ResultsCompared to EGFP titration, proviral DNA detection by qPCR was more accurate in assessing the number of infective particles in supernatants, such that average viral titres in terms of proviral copies per cell were two‐fold higher. Transgene mRNA expression was directly determined from the vectors used without the need for reporter assays. A new parameter, defined here as the ‘transcription index’ (TI), served to establish the association between transcribed transgenic mRNA and each proviral insertion. The TI represents the potential expression of every vector or insertion in each cell type, and is thus useful as a control parameter for monitoring preclinical or clinical protocols.ConclusionsThe practical use of qPCR is demonstrated as a valuable alternative to reporter genes for the assessment and surveillance of insertion numbers and transgene expression. In combination with protein expression, this approach should be capable of establishing safer therapeutic gene doses, avoiding the potential side effects of high transduction and expression levels. Copyright © 2006 John Wiley & Sons, Ltd.