bluuebunny/crossref_metadata_2025_split huggingface dataset:
K-12 Life Skills Education, Independence, and Employment of Autistic Individuals: Giving Voice to Autistic Adults
Authors: Zatz Jenna Christine , Harrison Judith R. 
Published: April 2024

AbstractAutistic adults are often challenged to engage in and complete life skill tasks independently and are underrepresented in employment. No prior study has explored the perceptions of autistic individuals regarding K-12 life skills experiences and postsecondary employment. As such, the purposes of this study were to explore the association between components of life skills instruction and employment for 12 autistic individuals, and to elicit the perspectives of and experiences in K-12 education and employment of six autistic adults. As this was a mixed methods study, surveys and semi-structured interviews were conducted. Results of Fisher’s test indicated no statistically significant associations between employment and instructional components; however, the associations between employment and household chores [Cramer’s V = .60]; cooking [Cramer’s V = .66]; one-on-one instruction [Cramer’s V = .63]; and field trips [Cramer’s V = .41]) were large. The associations between employment and job site training [Cramer’s V = .33] and token boards [Cramer’s V = .33]) were moderate. Three themes and 10 subthemes emerged. Specifically, participants remembered Memorable Components from K-12 instruction: (a) job site training, (b) field trips, and (c) household chores. Participants perceived Beneficial Practices as: (a) job site training and (b) skills learned. Participants described shortcomings of K-12 instruction as need (a) for more skills training, (c) for social skills training, (d) to eliminate unnecessary instruction and (e) to carefully consider student placement. In conclusion, participants described experiences that helped them gain and attain post-secondary employment. More specific individualized programming in K-12 instruction would be beneficial to develop independence and post-secondary employment.
Responses of Five Different Artificial Intelligence Chatbots to the Top Searched Queries About Erectile Dysfunction: A Comparative Analysis
Authors: Şahin Mehmet Fatih , Ateş Hüseyin , Keleş Anıl , Özcan Rıdvan , Doğan Çağrı , Akgül Murat , Yazıcı Cenk Murat 
Published: April 2024

Abstract
The aim of the study is to evaluate and compare the quality and readability of responses generated by five different artificial intelligence (AI) chatbots—ChatGPT, Bard, Bing, Ernie, and Copilot—to the top searched queries of erectile dysfunction (ED). Google Trends was used to identify ED-related relevant phrases. Each AI chatbot received a specific sequence of 25 frequently searched terms as input. Responses were evaluated using DISCERN, Ensuring Quality Information for Patients (EQIP), and Flesch-Kincaid Grade Level (FKGL) and Reading Ease (FKRE) metrics. The top three most frequently searched phrases were “erectile dysfunction cause”, “how to erectile dysfunction,” and “erectile dysfunction treatment.” Zimbabwe, Zambia, and Ghana exhibited the highest level of interest in ED. None of the AI chatbots achieved the necessary degree of readability. However, Bard exhibited significantly higher FKRE and FKGL ratings (p = 0.001), and Copilot achieved better EQIP and DISCERN ratings than the other chatbots (p = 0.001). Bard exhibited the simplest linguistic framework and posed the least challenge in terms of readability and comprehension, and Copilot’s text quality on ED was superior to the other chatbots. As new chatbots are introduced, their understandability and text quality increase, providing better guidance to patients.
Barriers to and Facilitators for Finding and Keeping Competitive Employment: A Focus Group Study on Autistic Adults With and Without Paid Employment
Authors: Brouwers Evelien P. M. , Bergijk Michel , van Weeghel Jaap , Detaille Sarah , Kerkhof Hanneke , Dewinter Jeroen 
Published: April 2024

Abstract

Purpose
The aim of the study was to gain more insight into barriers to and facilitators for finding and keeping competitive employment for autistic adults. Research questions were: (1) What barriers and facilitators do autistic adults report in finding and keeping competitive employment?; and (2) What are differences and similarities between autistic adults with and without paid employment regarding barriers and facilitators for sustainable employment?

Methods
Eight focus groups were conducted (N = 64 autistic adults). Four groups included only participants without paid employment (N = 24), and four groups consisted exclusively of participants with current paid employment (including part-time, N = 40). All discussions were audiotaped and transcribed verbatim to enable inductive thematic content analysis. Data were analyzed using ATLAS.ti 9.

Results
Ten themes and thirty-four subthemes were found. Many were interconnected. Themes facilitating sustainable employment included a positive workplace atmosphere, a supportive supervisor, being able to do work that aligns with interests and talents, favorable physical working conditions, coaching, higher self-insight, higher self-esteem, and proactivity. Most themes and subthemes emerged from both groups. Differences between the groups were that those with paid employment seemed to have experienced more friendly workplaces and supervisors, had received better coaching in finding and keeping employment, had higher self-insight and higher self-esteem, were more assertive and proactive.

Conclusions
As many (sub-)themes were interrelated, the results suggest that to improve work participation, particularly two key areas are promising: (1) to realize more friendly, well-being oriented and inclusive workplaces, and (2) to increase autistic adults’ self-insight into personal needs for positive wellbeing and self-knowledge regarding talents, wishes and well-being boundaries.
Obstacle Problems with Double Boundary Condition for Least Gradient Functions in Metric Measure Spaces
Authors: Kline Josh 
Published: April 2024

Abstract
In the setting of a metric space equipped with a doubling measure supporting a (1, 1)-Poincaré inequality, we study the problem of minimizing the BV-energy in a bounded domain

$$\Omega $$

Ω

of functions bounded between two obstacle functions inside

$$\Omega $$

Ω

, and whose trace lies between two prescribed functions on the boundary. If the class of candidate functions is nonempty, we show that solutions exist for continuous obstacles and continuous boundary data when

$$\Omega $$

Ω

is a uniform domain whose boundary is of positive mean curvature in the sense of Lahti, Malý, Shanmugalingam, and Speight (2019). While such solutions are not unique in general, we show the existence of unique minimal solutions. Since candidate functions need not agree outside of the domain, standard compactness arguments fail to provide existence of weak solutions as they are defined for the problem with single boundary condition. To overcome this, we introduce a class of

$$ \varepsilon $$

ε

-weak solutions as an intermediate step. Our existence results generalize those of Ziemer and Zumbrun (1999), who studied this problem in the Euclidean setting with a single obstacle and single boundary condition.
Effects of immigration on native entrepreneurship in the US: an analysis of self-employment over 1980–2018
Authors: Unel Bulent 
Published: April 2024

Abstract
This paper examines the causal impact of immigration on entrepreneurship among US-born non-Hispanic whites in non-agricultural private sectors from 1980 to 2018. Using self-employment as a proxy for entrepreneurship and distinguishing between incorporated individuals and unincorporated self-employed workers, I find a sizable negative impact of immigration on native self-employment. Importantly, this effect is consistent across incorporated and unincorporated self-employment and remains robust across demographic groups based on gender, age, and education. Results are robust to the choice of controls and estimation methods.
Belowground exploration by trees and shrubs
Authors: Putz Francis E. , Canham Charles D. , Ollinger Scott V. 
Published: April 2024

AbstractUnlike trees, shrubs (i.e., multiple-stemmed woody plants) do not need evenly spaced large diameter structural roots and therefore should be more responsive to heterogeneous distributions of soil resources and spread further per unit belowground biomass. We therefore hypothesized that compared to trees, shrubs respond more to asymmetric distributions of nutrients, reach nutrient-rich patches of soil faster, and do so with less below-ground biomass. To test these three hypotheses, we planted individual seedlings of shrubs (Cornus racemosa, Rhus glabra, and Viburnum dentatum) and trees (Acer rubrum, Betula populifolia, and Fraxinus americana) in the centers of sand-filled rectangular boxes. In one direction we created a stepwise gradient of increasing nutrients with slow-release fertilizer; in the other direction, no fertilizer was added. Seedlings were harvested when their first root reached the plexiglass-covered fertilized end of their box; time taken, above-ground biomass, and below-ground biomass per nutrient segment were determined. Shrubs and trees did not consistently differ in precision of root foraging (i.e., the ratio of biomass in the fertilized and unfertilized soil) or in rates (g/day) and efficiencies (cm/day) of lateral root growth. Interspecific variation appeared more related to species’ habitats than to growth form. The fastest and most efficient roots were produced by the shrub (R. glabra) and the tree (B. populifolia), both characteristic of poor and heterogeneous soils. Root foraging by R. glabra was also facilitated by rapid rhizomatous expansion.
Natural magnetite as an effective and long-lasting catalyst for CWPO of azole pesticides in a continuous up-flow fixed-bed reactor
Authors: Lopez-Arago Neus , Munoz Macarena , de Pedro Zahara M. , Casas Jose A. 
Published: April 2024

AbstractThe global occurrence of micropollutants in water bodies has raised concerns about potential negative effects on aquatic ecosystems and human health. EU regulations to mitigate such widespread pollution have already been implemented and are expected to become increasingly stringent in the next few years. Catalytic wet peroxide oxidation (CWPO) has proved to be a promising alternative for micropollutant removal from water, but most studies were performed in batch mode, often involving complex, expensive, and hardly recoverable catalysts, that are prone to deactivation. This work aims to demonstrate the feasibility of a fixed-bed reactor (FBR) packed with natural magnetite powder for the removal of a representative mixture of azole pesticides, recently listed in the EU Watch Lists. The performance of the system was evaluated by analyzing the impact of H2O2 dose (3.6–13.4 mg L−1), magnetite load (2–8 g), inlet flow rate (0.25–1 mL min−1), and initial micropollutant concentration (100–1000 µg L−1) over 300 h of continuous operation. Azole pesticide conversion values above 80% were achieved under selected operating conditions (WFe3O4 = 8 g, [H2O2]0 = 6.7 mg L−1, flow rate = 0.5 mL min−1, pH0 = 5, T = 25 °C). Notably, the catalytic system showed a high stability upon 500 h in operation, with limited iron leaching (< 0.1 mg L−1). As a proof of concept, the feasibility of the system was confirmed using a real wastewater treatment plant (WWTP) effluent spiked with the mixture of azole pesticides. These results represent a clear advance for the application of CWPO as a tertiary treatment in WWTPs and open the door for the scale-up of FBR packed with natural magnetite.
The behavioural effect of short-term cognitive and physical intervention therapies in old dogs
Authors: Bognár Zsófia , Szabó Dóra , Turcsán Borbála , Kubinyi Enikő 
Published: April 2024

AbstractEfforts to counteract age-related decline have resulted in the emergence of various interventions. However, everyday benefits are rarely reported in elderly people. Dogs provide an excellent model for studying aging and interventions due to their similarities to humans. Our aim was to investigate whether a combined physical and cognitive intervention (most effective in humans) could enhance the performance of pet dogs and lead to far transfer effects (improvement in not just the trained specific task). We examined the impact of three-month-long intervention therapies (cognitive, physical, combined) on the cognitive performance and behaviour of old, healthy dogs (N = 72; aged 7.68–14.54 years) using a 12-subtest behavioural test battery. We did not find the combined intervention group outperforming either the cognitive-only or physical-only therapy groups. Physical interventions, either alone or in combination, improved dogs' behavioural flexibility and social behaviour. Cognitive interventions, either alone or in combination, increased neophilia. Furthermore, all intervention therapies made dogs more engaged with their environment. Moreover, less old, around eight years old dogs, exhibited improved social behaviour, problem solving ability, and increased neophilia by their second test occasion. Additionally, dogs' performance was influenced by their health, training, daily play with the owner, and activity/excitability traits. In sum, both cognitive and physical intervention therapies can have an impact on the behaviour of old, healthy pet dogs. However, these therapies may be more effective when longer or applied at a younger age, as the healthy older dogs were less likely to show improvement.
Inference of fracturing zones and degrees of fluid content in the Las Tres Virgenes volcanic complex based on an analysis of seismic anisotropy
Authors: Chacón-Hernández Francisco , Campos-Enríquez Jose Oscar , Zúñiga Francisco Ramón , Lermo-Samaniego Javier 
Published: April 2024

AbstractAnisotropy strength in the Tres Vírgenes Volcanic Complex, Baja California Sur, Mexico, is analyzed employing 558 seismic events collected from 2009 to 2013. It was possible to delineate zones and volumes with the highest fracture densities, which are mainly located between the El Viejo and El Azufre volcanoes and around the La Reforma–El Azufre fault system, near some other mapped faults in the area (e.g., El Azufre, El Partido, El Volcán, El Viejo 1, and El Viejo 2 faults); likewise toward the La Virgen volcano and around the La Virgen-El Campamento and El Volcán faults. Individual delay times reached values of up to 0.16 s and an anisotropy percentage of up to 10.3%, with a pervasive anisotropy observed from at least a hypocentral distance of 3.5 km. High fracturing levels are observed from a depth of 7.0 km. Differences between splitting delays and the dominant frequency peaks obtained from the fast S phases allowed considering fracture systems with different degrees of fluid contents. Fractures with minor fluid contents were assumed for delay times higher than 0.03 s with lower dominant frequency peaks (< 1.0 Hz). Higher concentrations of fluid inclusions were assumed for splitting delays higher than 0.03 s but with larger dominant frequency peaks (> 1.0 Hz). Fractures systems chemically sealed or impermeable sealing caps were assumed for low splitting delays (< 0.02 s) with low dominant frequencies (< 1.0 Hz). These different fracture systems seem to be observed at least from 5- to 6-km depth intervals. Likewise, an analysis of the fast polarization directions with respect to different depth ranges (spanning from 3.0 to 8.0 km) has allowed observations of a strong NW–SE regional fracture system accompanied by minor NE–SW fracture systems. However, noteworthy variations from NW–SE to NE–SW, N–S, and E–W in fast polarization directions in rose diagrams have been preferentially observed for those seismic events deeper than 4–5 and 5–6 km in some areas, which could be indicating the location of magmatic bodies that probably caused the reorientation on fracture systems by changes in the local stress field. These magmatic bodies might be supported by a decrease in the dominant frequency peaks (lower than 1.0 Hz), percentage of anisotropy (from 0.1 to 2.5%), and S-wave velocities (from 1.0 to 2.7 km/s), which seem to be located from the 4.0-km depth but more concentrated from the 5–6-km depth interval.
Significance of definitive concurrent chemoradiotherapy for vulvar cancer: a Japanese Gynecologic Oncology Group nationwide survey study
Authors: Okonogi Noriyuki , Tsuchida Keisuke , Ando Ken , Ohno Tatsuya , Fujiwara Hiroyuki , Yoshihara Kosuke , Aoki Takuya , Takano Hirokuni , Takekuma Munetaka , Okamoto Aikou , Nishio Shin 
Published: April 2024

Abstract
Objective
This study aimed to show the results of radical radiation therapy (RT) and concurrent chemoradiotherapy (CCRT) for vulvar cancer (VC) based on data from a Japanese nationwide survey.

Materials and methods
We collected data from 108 institutions on cases of VC diagnosed between January 2001 and December 2010. Patients with histologically proven squamous cell carcinoma and adenocarcinoma with curative intent were selected, and 172 patients with VC were included in this study. The collected data were analyzed for overall survival (OS) using the Kaplan–Meier method. Univariate and multivariate analyses were performed to examine the prognostic factors for patients with VC.

Results
The median follow-up period was 16.8 (range; 3.2–154.8) months. Fifty-five patients received CCRT, and 117 patients received RT alone. The 2-year OS rates (95% confidence interval [CI]) for stages I, II, III, and IV were 77.9% (55.8–100.0), 71.9% (53.8–89.9), 55.4% (42.5–68.3), and 41.5% (27.3–55.7) respectively. Univariate analyses showed that the FIGO stage (p = 0.001), tumor diameter (p = 0.005), and lymph node (LN) status (p = 0.001) were associated with OS. The concurrent use of chemotherapy resulted in a significantly longer OS in Stage III (p = 0.013). Multivariate analysis showed that the hazard ratios (95% CI) for tumor diameter, positivity for LN metastasis, and RT alone (no concurrent chemotherapy) were 1.502 (1.116–2.021), 1.801 (1.287–2.521), and 1.936 (1.187–3.159), respectively.

Conclusions
Our analysis revealed that CCRT should be recommended, especially for Stage III VC patients. Further studies are warranted to determine who benefits from CCRT, considering primary tumor size and LN status.
The study was registered at the University Hospital Medical Information Network (protocol number: UMIN000017080) on April 8th, 2015.
NIFTP-adjusted risk estimation of Bethesda thyroid cytology categories should consider the indication for FNA according to TIRADS
Authors: Leoncini Andrea , Camponovo Chiara , Gamarra Elena , Piticchio Tommaso , Ruinelli Lorenzo , Rotondi Mario , Cantisani Vito , Treglia Giorgio , Trimboli Pierpaolo 
Published: April 2024

Abstract
Background
Non-invasive follicular thyroid neoplasm with papillary-like nuclear features (NIFTP) was firstly described in 2016. Since NIFTP is thought a non-malignant tumor, the Bethesda system for thyroid cytology proposes two estimations of risk of malignancy of the diagnostic categories, one considering NIFTP as cancer and another one considering it as a benign neoplasm. The present study aimed to review NIFTPs in a single center, re-assess them across categories of three Thyroid Imaging Reporting and Data Systems (TIRADSs), and define the indication for biopsy according to the category-specific size cut-offs.

Methods
The study period was from 2017 to 2023. The institutional database was searched for histologically proven NIFTPs with preoperative ultrasound images. NIFTPs were re-assessed according to the American College of Radiology (ACR), European (EU), and Korean (K) TIRADSs. The indication for biopsy was defined according to TIRADS category-specific size threshold.

Results
Twenty NIFTPs from 19 patients were included. The median size of the NIFTPs was 23 mm. According to ultrasound, 80–85% of NIFTPs were at low-intermediate risk and 5–15% at high risk without significant difference among the tree TIRADSs (p = 0.91). The indication for FNA, according to three TIRADSs, was found in 52–58% of cases with no significant difference among systems (p = 0.96).

Conclusion
NIFTPs have heterogeneous presentation according to TIRADSs with very low indication rate for FNA.
InDEL instability in two different tumoral tissues and its forensic significance
Authors: Gürel İpek , Aşıcıoğlu Faruk , Ersoy Gökhan , Bülbül Özlem , Öztürk Tülin , Filoğlu Gönül 
Published: April 2024

Abstract
There may be cases where malignant tumor samples can be used for forensic DNA profiling studies. STRs are the first systems preferred in forensic science laboratories for identification purposes. However, genetic instability in tumoral tissues causes STR polymorphism to change, leading to erroneous results. On the other hand, insertion/deletion polymorphism (InDels) are used as genetic markers in forensic science, as they have features that make both STR and SNPs preferable. Although previous studies approved that STR instability is observed in many different tumors, there are only a few studies that have displayed the instability of InDels in tumoral tissues before. In this study, it was aimed to determine whether instability is observed in formalin-fixed paraffin-embedded breast and thyroid tumoral tissues at 36plex InDel Panel. A total of 47 cases, 26 of which were diagnosed as breast cancer and 21 as thyroid cancer, were included in the study. In 21 of 26 (80.76%) breast cancers mutational changes were observed, however only 6 of 21 (28.57%) thyroid carcinoma cases displayed instability.Moreover, in these six cases, mutations were detected at only 1 or 2 loci. The most common change in both tissues was loss of heterozygosity. These findings suggest that paraffin embedded tissues of thyroid tumor can be used in cases of forensic genetic identification, however paraffin embedded breast cancer tissues should be examined with care. In conclusion, low InDel mutation rates compared to STR instability, make InDel analysis from paraffin blocks suitable for forensic genetic identification. However, researchers should keep in mind that there may be differences between the profiles of the tumoral tissues taken as reference and the actual case. In addition, by incorporating additional markers such as SNPs and microhaplotypes with low mutation rates into the study alongside Indels, researchers can significantly enhance the discrimination power in identification processes.
Use of an Impact Recording Device to Determine the Risk of Bruising in Packaged Potatoes
Authors: Hendricks R. L. , Olsen N. , Thornton M. , Hatzenbuehler P. 
Published: April 2024

AbstractHandling potatoes individually or collectively in packages can create opportunities for potatoes to develop quality defects including blackspot and shatter bruise. Three trials were conducted to examine how handling packaged potatoes can influence the risk for physical damage including shatter and blackspot bruise. An impact recording device was used to record peak acceleration (max g-force) in common fresh market packaging options (boxes or bales) at four drop heights (15 to 91 cm) on to three different surface types. When boxed potatoes were dropped onto concrete or a plastic slip, the potatoes on the bottom of the box had the highest risk of damage (greater than 100 g-force). When drop heights were lowered, or when cushioning material was added to hard surfaces (e.g., wooden pallet on top of concrete floor), the risk for impact damage was decreased throughout the box. When palletizing boxed potatoes, the risk of bruise decreased after the first layer was stacked on the pallet. Drop heights need to be below 15 cm, especially when making the first layer in a palletized stack of packaged potatoes to reduce potential bruising. The risk of high peak accelerations was not seen in the dropped or stationary bales for any of the drop heights examined. This study provided information for educating personnel on handling packaged potatoes and determining situations in which robotic stacking equipment needs to be adjusted to lower drop heights of packaged potatoes.