bluuebunny/crossref_metadata_2025_split huggingface dataset:
Unilateral arytenoid lateralisation for the treatment of laryngeal paralysis in four cats
Authors: White R. N. 
Published: April 2008

ABSTRACTA unilateral arytenoid lateralisation procedure was successfully performed in four cats with either unilateral or bilateral laryngeal paralysis. All of the cats were presented for the investigation of signs of exercise‐related respiratory embarrassment and stridor. Other clinical signs seen included altered vocalisation, an inability to purr, coughing and lethargy. A diagnosis of either bilateral or left or right unilateral laryngeal paralysis was made in each case following visual inspection of the vocal folds with the aid of a laryngoscope under a light plane of anaesthesia. In two cases the paralysis was bilateral and the condition was considered to be either congenital or idiopathic. In the other two cases the condition was unilateral and was considered to be iatrogenic as a result of previous surgical procedures. The results of this technique were considered excellent in all cases.
Dystocia in the cat: A retrospective study of 155 cases
Authors: Ekstrand C. , Linde‐Forsberg C. 
Published: April 2008

ABSTRACTIn a retrospective study of 155 cases of feline dystocia, 67‐1 per cent were of maternal origin, mainly caused by uterine inertia, while 29‐7 per cent were of fetal origin, mainly resulting from malpresentations/malorientations and deformities. Its breed incidence was somewhat higher in Persian cats than in other breeds and considerably lower in Norwegian forest cats. Litter size was not related to the risk of developing dystocia. Ninety‐seven cats (62.5 per cent) were treated with calcium and, or, oxytocin. Medical treatment was successful in only 29 cases (29.9 per cent). Caesarean sections were performed on 123 (79.4 per cent) of the cats that were brought to the hospital because of dystocia. In 55 cases (35.5 per cent) a caesarean section was performed without prior attempts at medical treatment.
M‐mode echocardiography study in growing Spanish mastiffs
Authors: Bayón A. , del Palacio M. J. Fernández , Montes A. M. , Panizo C. Gutiérrez 
Published: April 2008

ABSTRACTThe growth of the heart in proportion to body‐weight was studied by M‐mode echocardiography in 66 Spanish mastiffs aged from one to 12 months and from two to four years. Measurements of the right and left ventricular cavities, septal and parietal wall thicknesses, aorta, left atrium, D‐E excursion of the mitral valve and distance between the maximum aperture of the mitral valve and the interventricular septum, were shown to have a curvilinear increase closely related to the development of bodyweight. Least squares regression analysis of the logarithmically transformed data provided the power‐law equations relating each echocardiographic measurement to bodyweight. The exponential powers of bodyweight varied from 0.22 to 0.45. From the direct measurements the following cardiac indices were determined: ratio of right/left ventricular cavity, shortening fraction, percentage of septal and parietal wall thickness and ratio of aorta/left atrium. The highest coefficient of determination was for the right ventricular/left ventricular ratio.
Efficacy of daily amitraz on generalised demodicosis in dogs
Authors: Medleau L. , Willemse T. 
Published: April 2008

ABSTRACTFifty dogs with generalised demodicosis were treated with daily applications of 0·125 per cent amitraz solution over half the body. This was applied once a day, alternating the body half treated. Nine dogs were lost to follow‐up; the remaining dogs were classified as either a success (25 dogs, 61 per cent) or a failure (16 dogs, 39 per cent) according to their response to treatment. Eight of the failures were due to persistent demodicosis and eight relapsed within one year after treatment. All eight of the relapsed dogs were cured after a second course of daily amitraz treatment. For the 25 dogs considered treatment successes, the median duration of treatment was 6·5 weeks (range, three weeks to nine months), and the median interval from completion of treatment to last post treatment evaluation was 3·4 years (range, two to four‐and‐a‐half‐years). Including the eight dogs that were cured after retreatment, the daily amitraz applications were curative in 33 of 41 dogs (80 per cent) with generalised demodicosis.
Multisystemic inflammatory disease in a borzoi dog
Authors: Cheeseman M. T. , Kelly D. F. , Horsfall K. L. 
Published: April 2008

ABSTRACTA six‐week‐old female borzoi puppy from a brother‐sister mating developed a generalised illness characterised by anorexia, temporary intention tremor, episodic pyrexia, tachypnoea, conjunctivitis, otitis and neck pain. Haematological abnormalities included an inflammatory leukogram and regenerative anaemia. Blood cultures remained sterile; clinical chemistry values were unremarkable. The puppy had recurrent seizures and was euthanased when 18 weeks old. Post mortem examination revealed a multisystemic inflammatory disease involving thyroids, lymph nodes, spleen, pancreas, bladder and lung, but no lesions to account for the neurological signs. The cause of this generalised disease was not recognised. The histological features are unusual and resemble those described in other dogs of this breed.
Aural cholesterol granuloma in a dog
Authors: Cox C. L. , Payne‐Johnson C. E. 
Published: April 2008

ABSTRACTA five‐year‐old female Irish setter was referred for surgery for a left‐sided aural mass. The dog was generally well, but had signs of left‐sided otalgia for one week. Biopsy identified the lesion as a cholesterol granuloma. The mass was removed three weeks later by a total canal ablation/lateral bulla osteotomy. The dog recovered from surgery without any complications. Ten months later, there was no evidence of recurrence. The purpose of this paper is to report the clinical and histopathological findings of this unusual form of granuloma which has not previously been reported in the canine ear.
A review of Pathological diagnoses made from 87 canine splenic biopsies
Authors: Day M. J. , Lucke V. M. , Pearson H. 
Published: April 2008

ABSTRACTThe pathological findings in 87 cases of canine splenic abnormality recognised clinically by abdominal palpation or radiography, or at exploratory laparotomy, are presented. The most common diagnosis was of splenic neoplasia (n = 38) and the most frequently recognised canine splenic neoplasm was haemangiosarcoma (17 of 38 cases). Benign splenic enlargement secondary to nodular hyperplasia (n = 6), haematoma (n = 16) or non‐specific changes including congestion, haemorrhage, extramedullary haemopoiesis and haemosiderin deposition (n = 14) was also recognised. A diagnosis of non‐specific pathology was more frequently recorded when portions of spleen, as opposed to the entire organ, were submitted for assessment. Splenic infarction, with (n = 3) or without (n = 7) torsion, abscessation (n = 2) and focal mast cell proliferation (n = 1) accounted for the remainder of the cases. Clinical follow‐up was available for 35 cases and revealed good long‐term survival in cases of splenic haematoma or haemangioma, with relatively poor survival with a diagnosis of splenic haemangiosarcoma or anaplastic sarcoma. A range of splenic disorders was recognised in dogs of the labrador breed (16 of 87 cases) and three of 17 cases of haemangiosarcoma occurred in German shepherd dogs. The possible predisposition of dogs of these breeds to splenic disorders is discussed.
Neuroaxonal dystrophy in a litter of papillon pups
Authors: Franklin R. J. M. , Jeffery N. D. , Ramsey I. K. 
Published: April 2008

ABSTRACTA litter of five 14‐week‐old papillon puppies was referred for investigation of pelvic limb ataxia. Clinical examination revealed signs of ataxia, hypermetria and depressed postural reflexes affecting all four limbs. The severity of these signs varied between members of the litter. The condition became progressively worse and by 19 weeks of age all but the least severely affected pup (the single male of the litter) had deteriorated to the point that euthanasia was indicated on humane grounds. Pathological examination revealed widespread changes in both white and grey matter of the neuraxis caudal to the fore‐brain, particularly involving the dorsolateral white matter of the spinal cord, which were characterised by axonal swellings typical of neuroaxonal dystrophy.
Feline asthma syndrome: A retrospective study of the clinical presentation in 29 cats
Authors: Corcoran B. M. , Foster D. J. , Fuentes V. Luis 
Published: April 2008

ABSTRACTFeline asthma syndrome (FAS) is a clinical condition characterised by recurrent bouts of coughing, wheezing and, or, dyspnoea. While the aetiology is unproven, the condition is believed to involve a type I immediate hypersensitivity reaction to inhaled allergens. In this paper the clinical data from 29 cats, where a diagnosis of FAS was made, are assessed retrospectively. The most common clinical presentation was recurrent bouts of coughing (n=26) and dyspnoea (n=21), Radiographic changes were noted in 24 cats, which included increased bronchial (n=5), interstitial (n=7) and mixed (n=12) (bronchial and interstitial) patterns. Right middle lung lobe collapse was noted in two cats. Abnormal bronchial cytology was present in 16 cats. A predominant eosinophilic sample was collected in only three cats. There were minimal changes in differential white cell counts, and mild eosinophilia was found in only five cats. Prednisolone alone was the most effective therapy, although avoidance of putative aeroallergens and antibacterial therapy was effective in some. On the basis of the data from these cases it would appear that the diagnosis of FAS depends largely on the clinical presentation and radiographic findings. The value of ancillary tests in the diagnosis of FAS appears to be limited.
Sterile idiopathic pedal panniculitis in the German shepherd dog ‐ clinical presentation and response to treatment of four cases
Authors: Paterson S. 
Published: April 2008

ABSTRACTFour cases of sterile idiopathic pedal panniculitis are described in the German shepherd dog. All the dogs presented with characteristic clinical signs of localised panniculitis dorsal to the midline of the carpal or tarsal pads of one or more legs. Diagnostic procedures did not identify a cause for the panniculitis and none of the cases had a history of penetrating foreign bodies. All cases failed to respond to antibiotic therapy but did respond to anti‐inflammatory doses of prednisolone. The lesions in three dogs relapsed once the levels of steroids were reduced. However, in two of the cases oral vitamin E therapy at a dose of 300 iu twice daily acted in a steroid sparing capacity. In a fourth case, vitamin E acted to control the clinical signs without steroid therapy.
Surgical repair of fracture of the os penis in a dog
Authors: Kelly S. E. , Clark W. T. 
Published: April 2008

ABSTRACTAn eight‐year‐old male Australian cattle dog cross was presented with complete urethral obstruction secondary to fracture of the os penis which had occurred two years earlier. Obstruction was associated with callus and fibrous tissue proliferation compressing the urethra at the fracture site. The problem was satisfactorily resolved by removing excess bone and fibrous tissue and stabilising the fracture with a stainless steel finger plate.
Diagnosis and prognosis of chronic hepatitis and cirrhosis in dogs
Authors: Sevelius E. 
Published: April 2008

ABSTRACTThe purpose of this investigation was to evaluate the significance of enzymatic and biochemical analyses in the classification of chronic inflammatory liver disease and to evaluate the prognosis of these diseases. Chronic hepatitis and cirrhosis were diagnosed by histopathological examination in 79 dogs. Decreased appetite and lethargy were the most common owner complaints (46/79). Vomiting and, or, diarrhoea were reported in 27/79 dogs. Ascites was the most common clinical sign (43/79), whereas icterus was a more unusual finding demonstrated in 16/79 dogs. Liver cirrhosis was diagnosed most frequently, in 33/79 dogs, followed by chronic progressive hepatitis (22/79), chronic cholangiohepatitis (13/79), and chronic non‐specific hepatitis (11/79). Hypoalbuminaemia was the most consistent biochemical aberration in liver cirrhosis (25/26) and in chronic progressive hepatitis (13/18). These diseases also showed normal to mildly increased concentrations of serum alanine aminotransferase (ALT) and serum γ‐glutamyl transferase (GGT) and a moderate to marked increase of serum alkaline phosphatase (ALP) and fasting serum bile acid (SBA) concentrations. As expected, icterus and markedly elevated ALT, ALP, GGT and SBA levels were demonstrated in chronic cholangiohepatitis. In this disease hypoalbuminaemia was shown in 6/12 dogs, whereas in dogs with chronic non‐specific hepatitis, mean SBA and albumin concentrations were normal. In liver cirrhosis the prognosis was poor, with 94 per cent of the dogs dead within one week of established diagnosis. For dogs with the other types of chronic hepatitis the prognosis was more favourable with the mean survival time ranging from 21‐1 to 36‐4 months.
Carprofen as an analgesic for postoperative pain in cats: Dose titration and assessment of efficacy in comparison to pethidine hydrochloride
Authors: Lascelles B. D. X. , Cripps P. , Mirchandani S. , Waterman A. E. 
Published: April 2008

ABSTRACTThe aim of this study was to titrate the optimal dose of carprofen for single dose usage, for alleviating postoperative pain, under a double‐blind and randomised protocol, using both negative and positive controls. Renal tolerance was assessed by screening plasma urea and creatinine. Pre‐ and postoperative assessment of pain and sedation was made using a dynamic and interactive visual analogue scoring system in 60 cats undergoing ovariohysterectomy. The cats were randomly assigned to one of six groups: (1) carprofen at 1‐0 mg/kg subcutaneously (sc); (2) carprofen at 2‐0 mg/kg sc; (3) carprofen at 4‐0 mg/kg sc; (4) pethidine at 5‐0 mg/kg intramuscularly (im), (5) pethidine at 10‐0 mg/kg im; and (6) no analgesics (injection of saline). All injections were given postoperatively on tracheal extuba‐tion and administered in a double‐blind manner. Assessments were made up to 20 hours post extubation. Prior to induction and at 20 hours post extubation, blood samples were taken for laboratory analysis of the urea and creatinine content to check for any adverse effect on renal function. Cats given pethidine did not appear more sedated than the groups receiving carprofen or saline. Cats receiving carprofen were in less pain postoperatively overall, with 4‐0 mg/kg being the most effective dose rate (significantly better than the other doses of carprofen at four and eight hours post extubation). The highest dose of pethidine provided significantly better analgesia than the highest dose of carprofen up to two hours post extubation, but from two to 20 hours post extubation carprofen at 4‐0 mg/kg provided significantly better analgesia than the pethidine. None of the analgesic regimens appeared to affect renal function adversely, as measured by urea and creatinine levels.
Periodontal disease and leucopenia
Authors: Lonsdale T. 
Published: April 2008

ABSTRACTPeriodontal disease is rare in nature but widespread in domestic dog and cat populations. Unnatural diets are known to facilitate the buildup of oral microbial communities which then interact with host‐immune defences giving rise to periodontitis. Eight of 14 animals undergoing dental treatment and dietary change at a suburban veterinary practice were investigated and found to have low leucocyte counts. Follow‐up testing revealed changes averaging a 77·7 per cent increase with concomitant ‘subjective good health’. These findings serve to cast doubt on the commonly used haematological reference ranges where the subject animals may have suffered from periodontal disease. The demonstrated reversibility of white cell depression associated with periodontal disease should provide a focus for further research.
Treatment of canine nictitans plasmacytic conjunctivitis with 0–2 per cent cyclosporin ointment
Authors: Read R. A. 
Published: April 2008

ABSTRACTNictitans plasmacytic conjunctivitis, commonly referred to as plasma cell infiltrate of the nictitans or plasmoma, was diagnosed in 12 dogs (23 eyes) on the basis of clinical signs and nictitans conjunctival biopsy specimens. These dogs underwent a clinical therapeutic trial with twice daily 0·2 per cent cyclosporin ophthalmic ointment. Response to therapy was monitored over a six‐week period and repeat biopsy specimens were then taken. Significant (P<0·05) reductions between pre‐ and post trial scores were recorded for: mucopurulent ocular discharge quantity; degree of bulbar conjunctival hyperaemia; areas of nictitans hyperaemia, thickening and depigmentation. Schirmer tear test values significantly increased between the start and end of treatment. Biopsy specimens were subjected to selective detection procedures for plasma cells (methyl green‐pyronin staining) and T lymphocytes (CD3 antigen labelling). Mean cell counts showed a significant reduction in plasma cell numbers, but the trend towards reduced T lymphocyte numbers was not significant.
Focal cystic endometrial hyperplasia in a bitch
Authors: Cockcroft P. D. 
Published: April 2008

ABSTRACTRapid abdominal enlargement and weight gain occurred in a four‐year‐old Rhodesian ridgeback bitch in late oestrus. The bitch was nulliparous. Severe cardiovascular dysfunction followed and an exploratory laparotomy was performed. A large, single, spheroid mass weighing 17 kg was located in the middle section of the left uterine horn. A diagnosis of sterile, focal, cystic endometrial hyperplasia was made from gross pathology, histopathol‐ogy and bacteriology. The bitch made a complete recovery following an ovariohysterectomy.
Ultrasonographic findings in a basenji with immunoproliferative enteropathy
Authors: Spohr A. , Koch J. , Jensen A. L. 
Published: April 2008

ABSTRACTThe ultrasonographic findings in a one‐and‐a‐half‐year‐old female basenji with immunoproliferative enteropathy are described. On ultrasonographic examination, generalised thickening of the small bowel wall was found, ranging between 4 and 6 mm. The normal layered appearance of the intestinal wall was replaced by three distinct layers; an innermost enlarged hyperechogenic layer; an enlarged poor echogenic layer, and an outer hyperechogenic layer. These findings are consistent with the histopathological appearance of this particular chronic inflammatory bowel disease, since the inner layer probably represents the infiltrated mucosa, the middle layer the infiltrated lamina propria and the outer layer the serosa. Thus, the ultrasonographic finding of generalised thickening of the intestinal wall in a basenji presenting with chronic diarrhoea, weight loss, anorexia or vomiting is strongly indicative of immunoproliferative enteropathy.
Trypanosoma congolense infection in two dogs
Authors: Harrus S. , Harmelin A. , Presenty B. , Bark H. 
Published: April 2008

ABSTRACTTrypanosomiasis, caused by Trypanosoma congolense, was diagnosed for the first time in Israel in two boxer dogs imported from Kenya. The dogs developed clinical signs two days after arrival and succumbed to the disease within four days. The major clinical and clinicopathological findings included anaemia, haemorrhages, lymphadenomegaly, hepatosplenomegaly and neurological signs. Histopathology showed lymphocytic‐plasmacytic infiltration in the skin, brain, meninges, kidney and liver.
Neutrophil phagocyte dysfunction in a weimaraner with recurrent infections
Authors: Hansen P. , Clercx C. , Henroteaux M. , Rutten V. P. M. G. , Bernadina W. E. 
Published: April 2008

ABSTRACTA five‐and‐a‐half‐month‐old male weimaraner with severe recurrent bacterial infections was assessed for immunocompetence. Results revealed a low serum immunoglobulin G concentration and defective neutrophil phagocytosis.
Megaoesophagus and glucocorticoid‐deficient hypoadrenocorticism in a dog
Authors: Whitley N. T. 
Published: April 2008

ABSTRACTA seven‐year‐old German shepherd dog was referred for acute onset regurgitation. Muscle weakness and severe dermatological disease were present. Thoracic radiographs revealed generalised megaoesophagus. Diagnostic testing revealed glucocorticoid deficiency, and rapid resolution of the megaoesophagus followed appropriate supplementation. The dog made a full recovery. Unique features of this case include a transiently positive antinuclear antibody titre and clinical features of myasthenia gravis.
Spondylosis deformans in the boxer: Estimates of heritability
Authors: Langeland M. , Lingaas F. 
Published: April 2008

ABSTRACTThis study presents the estimates of heritability for spondylosis deformans in the boxer based on 353 offspring from 24 randomly selected sires, each with at least three radiographically investigated offspring. The estimated heritability (h2) for maximum degree of osteophyte development was high, both when estimated by paternal half‐sib correlation (0·42) and by the regression of offspring based on the parents (0·62). The heritability for the number of affected discs estimated by paternal half‐sib correlation was also high (0·47). The estimate of heritability for the number of affected discs based on regression of offspring on the parents was lower at 0·13. All heritabilities had large standard errors. A positive phenotypic correlation between spondylosis deformans and hip dysplasia was observed. Assuming a significant portion of the correlation is genetic, this fact may permit selection against spondylosis deformans without negatively influencing the incidence of hip dysplasia. Since the incidence of spondylosis deformans is high even in young dogs, it should be possible to detect a large proportion of genetically predisposed animals by radiographic examination of the spine at one year of age; at the same time that dogs are presented for a routine test for hip dysplasia.
Dermoid sinus and spinal malformations in a Yorkshire terrier: Diagnosis and follow‐up
Authors: Fatone G. , Brunetti A. , Lamagna F. , Potena A. 
Published: April 2008

ABSTRACTAn unusual case of a Yorkshire terrier with a dermoid sinus associated with multiple spinal/costal malformations is described. The dog presented with ataxia and pain in the dorsal thoracic region. Diagnostic characterisation of the lesions was obtained with radiography, myelography and computed tomography. After surgical removal of the sinus, the dog showed marked clinical improvement over a two‐year period.
Spinal meningeal sarcoma in a rottweiler puppy
Authors: Hopkins A. L. , Garner M. , Ackerman N. , Chrisman C. L. , Eskin T. 
Published: April 2008

ABSTRACTAn 11‐week‐old rottweiler puppy was presented for evaluation of progressive paraparesis, urinary and faecal incontinence. Radiography and myelography revealed widening of the vertebral canal and remodelling of several lumbar vertebrae associated with an intramedullary spinal mass. Magnetic resonance imaging revealed an extensive, heterogeneous mass involving the lumbosacral spinal cord. Histopathological examination indicated a meningeal sarcoma with very varied cytological architecture.
Melanocytic neoplasia in the cat
Authors: Day M. J. , Lucke V. M. 
Published: April 2008

ABSTRACTClinical features and histopathological details from 13 cases of melanocytic neoplasia in the cat are presented. The series includes cases of intraocular melanoma (n=5), limbal melanoma (n=2), dermal melanoma (n=5) and one case of metastatic melanoma for which a primary site was not identified. In the case of the intraocular tumours, there was apparent correlation between the degree of cellular pleomorphism, the mitotic rate and the extent of local infiltration. Such an association was not identified for the melanomas arising from the limbus or skin.