bluuebunny/crossref_metadata_2025_split huggingface dataset:
Evaluation of the Carbohydrate Recognition Domain of the Bacterial Adhesin FimH: Design, Synthesis and Binding Properties of Mannoside Ligands.
Authors: Sperling Oliver , Fuchs Andreas , Lindhorst Thisbe K. 
Published: January 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
WTDWTR: What To Do With This Reaction? A New Programm in the Field of Computer‐Aided Synthesis Design — Application to the Diels—Alder Reaction.
Authors: Barone Rene , Attolini Mireille , Arbelot Michel , Chanon Michel 
Published: January 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
NIPALSTREE: A New Hierarchical Clustering Approach for Large Compound Libraries and Its Application to Virtual Screening.
Authors: Boecker Alexander , Schneider Gisbert , Teckentrup Andreas 
Published: January 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Ab initio Kinetic Modeling in Radical Polymerization: A Paradigm Shift in Reaction Kinetic Analysis.
Authors: Coote Michelle L. , Barner‐Kowollik Christopher 
Published: January 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Synthesis of Carboxylic Acid and Ester Mid‐Functionalized Polymers Using RAFT Polymerization and ATRP.
Authors: Malic Nino , Evans Richard A. 
Published: January 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Synthesis and Evaluation of Antimicrobial Activity of Novel Hydrazino and N‐Benzylidinehydrazino‐Substituted 4,8‐Dihydro‐1H,3H‐pyrimido[4,5‐d]pyrimidin‐2,7‐dithiones.
Authors: Sharma Pratibha , Rane Nilesh , Pandey Priti 
Published: January 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Theory of the Kondo Lattice: Competition Between Kondo Effect and Magnetic Order
Authors: Coqblin B. , Nunez‐Regueiro M. D. , Theumann A. , Iglesias J. R. , Magalhaes S. G. 
Published: January 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
New Insights on the Anticancer Properties of Dietary Polyphenols
Authors: Fresco P. , Borges F. , Diniz C. , Marques M. P. M. 
Published: January 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Cupreines and Cupreidines: An Emerging Class of Bifunctional Cinchona Organocatalysts
Authors: Marcelli Tommaso , van Maarseveen Jan H. , Hiemstra Henk 
Published: January 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Cubanes, Fenestranes, Ladderanes, Prismanes, Staffanes and Other Oligocyclobutanoids
Authors: Hopf Henning , Liebman Joel F. , Perks H. Mark 
Published: January 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Enhanced efficiency due to the use of achiral additives in the optical resolution of 1‐phenylethylamine by its glutaric acid derivative
Authors: Schindler József , Egressy Márton , Bereczki Laura , Pokol György , Fogassy Elemér , Marthi Katalin 
Published: January 2007

AbstractRacemic 1‐phenylethylamine was optically resolved by its own derivative formed with glutaric acid namely (+)‐(R)‐N‐(1‐phenylethyl)glutaramic acid. The amide acid resolving agent was synthesized from (+)‐(R)‐1‐phenylethylamine by N‐derivatization. The glutaric acid derivative was the next in a homologous series of dicarboxilic acid derivatized resolving agents of racemic 1‐phenylethylamine. Resolution results obtained with the oxalic, malonic, and succinic acid derivatives were previously discussed1. Each of the above derivative resolving agents could be successfully applied as resolving agents of 1‐phenylethylamine. The efficiency of the present optical resolution using (+)‐(R)‐N‐(1‐phenylethyl)glutaramic acid resolving agent was remarkably inferior to the results obtained by its shorter chained homologues1. Use of achiral additives, like urea, thiourea, N‐methylurea, and N,N′‐dimethylurea caused large increase in the efficiency of the resolution by (+)‐(R)‐N‐(1‐phenylethyl)glutaramic acid resolving agent. Precipitated salts obtained in the resolutions performed in the presence of the additives were investigated by thermoanalysis, X‐ray powder diffraction, and optical microscopy. Based on the analytical data, the improvement of the resolution results was attributed to the influence of the additives on the crystal nucleation processes of the diasteromeric salts. Chirality, 2007. © 2007 Wiley‐Liss, Inc.
Aldosterone‐sensitive neurons of the nucleus of the solitary tract: Multisynaptic pathway to the nucleus accumbens
Authors: Shekhtman Eugenia , Geerling Joel C. , Loewy Arthur D. 
Published: January 2007

AbstractThe nucleus accumbens (NAc) is part of a forebrain system implicated in reward, motivation, and learning. NAc neurons become activated during various ingestive activities, including salt intake. A subset of neurons within the nucleus tractus solitarius (NTS) shows c‐Fos activation during prolonged sodium deprivation in rats. These neurons express mineralocorticoid receptors and the enzyme 11‐β‐hydroxysteroid dehydrogenase type 2 (HSD2), which makes them selectively sensitive to aldosterone—an adrenal hormone that modulates sodium appetite. Here we tested whether these neurons project multisynaptically to the core or shell subregions of the NAc. Pseudorabies virus (PRV)—a retrograde transneuronal tracer—was injected into the NAc in rats and after 3–4 days PRV‐infected HSD2 neurons were identified. PRV injections into the NAc core yielded greater numbers of PRV‐labeled HSD2 neurons than did comparable injections into the NAc shell. Transneuronal labeling was also found in brainstem sites that receive direct projections from HSD2 neurons, namely, lateral parabrachial and prelocus coeruleus nuclei. In other experiments a retrograde neural tracer (cholera toxin β‐subunit) was injected into the NAc. Extensive retrograde labeling was found in the midline thalamus and frontal cortical regions, but no cells were labeled in the NTS or parabrachial region. These findings indicate that the HSD2 neurons project via a multisynaptic pathway to the NAc, which may be relayed sequentially through two sites: the dorsolateral pons and the paraventricular thalamic nucleus. HSD2 neurons may be part of an ascending pathway involved in the salt‐seeking behavior of sodium‐depleted rats. J. Comp. Neurol. 501:274–289, 2007. © 2007 Wiley‐Liss, Inc.
Adsorption, Diffusion and Desorption of Chlorine on and from Rutile TiO2{110}: A Theoretical Investigation
Authors: Inderwildi Oliver R. , Kraft Markus 
Published: January 2007

AbstractThe adsorption, diffusion and desorption of chlorine on and from stoichiometric, reduced and partially reduced (defective) rutile TiO2{110} are investigated using ab initio density functional theory (DFT) calculations. Theoretical results are compared with experimental investigations, and microkinetic simulations based on DFT values are then used to verify the diffusion mechanisms assumed in the experimental investigations.
Dynamic fractal unifying interaction confirmed with magnetospheric behavior and orbital data
Authors: Savov Eugene 
Published: January 2007

AbstractThe solar wind makes the magnetosphere to expand and contract as indicated by the expansions and contractions of the auroral oval due to balancing of the dynamic pressure of the ambient space plasma at inner and outer magnetic lines. This self‐similar magnetospheric behavior elucidates the controversial magnetic storm‐substorm relationship and reveals the 3D‐spiral structure of magnetic interaction. The found self‐similarly evolving structure of one seen as fundamental interaction suggests dynamic fractal unifying interaction that builds a firework universe having 3D‐spiral code. The unifying interaction is described with equation drawn in new fundamental dynamic fractal framework. The equation of unifying interaction converges to the inverse square laws and the principle of uncertainty at laboratory scales. The dynamic fractal fundamental framework is made of one 3D‐spirally‐faster‐inward contracting and expanding, oscillating, basic matter. It simply accounts for observed constant speed of light and for the creation of bright and dark bands on a screen behind a tiny slit. The dynamic fractal framework is quantitatively confirmed with the orbital data for the Milky Way Galaxy, the Sun, the Earth, and the triple asteroid system 87 Sylvia. Many testable predictions are also made. The presented new fundamental dynamic fractal framework allows qualitative and quantitative modeling and simplification. © 2007 Wiley Periodicals, Inc. Complexity 12: 61–76, 2007
A high‐throughput 3‐parameter flow cytometry‐based cell death assay
Authors: Buenz Eric J. , Limburg Paul J. , Howe Charles L. 
Published: January 2007

AbstractApoptosis plays a role in many disease states, and the evaluation of novel therapeutics that alters the apoptotic cascade is an area of intense investigation. However, many generally available methods to evaluate cell death are either time consuming, imprecise, or both. We report a system that permits simultaneous evaluation of three apoptotic markers (cell membrane integrity, mitochondrial membrane potential, and cell cycle progression) with minimal technical manipulation. This system is particularly well‐suited for toxicologic evaluation of novel compounds and profiling of new apoptosis‐inducing agents. © 2007 International Society for Analytical Cytology
Drug resistance in B‐cell chronic lymphocytic leukemia: Predictable by in vitro evaluation with a multiparameter flow cytometric cytotoxicity assay
Authors: Zhong Yanping , Bakke Antony C. , Fan Guang , Braziel Rita M. , Gatter Ken M. , Leis Jose F. , Maziarz Richard T. , Huang James Z. 
Published: January 2007

AbstractBackground:Patients with B‐cell chronic lymphocytic leukemia (B‐CLL) often demonstrate variable responses to similar treatments. It would be highly desirable to develop a personalized therapeutic strategy for selection of appropriate drugs or regimens based on the drug sensitivity profiles of leukemic cells from individuals.Methods:We applied a multiparameter flow cytometric drug cytotoxicity assay to evaluate drug effects specifically on B‐CLL cells from 43 individuals after leukemic cells were incubated in vitro with fludarabine, chlorambucil, cladribine, or prednisolone.Results:We demonstrated that different B‐CLL cell populations from 43 individuals showed a marked variability in drug sensitivity. In vitro resistance to fludarabine was greatest in B‐CLL cells with deletions of p53, a cytogenetic abnormality that is almost invariably associated with a poor therapeutic response clinically.Conclusions:In vitro drug sensitivity profiles analyzed by a multiparameter flow cytometric cytotoxicity assay may serve as a tool to facilitate individualized selection of appropriate drugs for treatment in B‐CLL. Prospective trials will be needed to validate the clinical utility of this flow cytometric cytotoxicity assay. © 2007 International Society for Analytical Cytology
Robust JPEG image transmission using unequal error protection and code combining
Authors: Fowdur T. P. , Soyjaudah K. M. S. 
Published: January 2007

AbstractJPEG image transmission over noisy channels is highly problematic due to the sensitivity of the JPEG bit stream to error propagation. The use of resynchronization markers and channel coding do not alleviate the problem completely thus making retransmissions inevitable. In packetized image transmission, image packets are repeatedntimes, to ensure reliable transmission. This paper proposes a new unequal error protection (UEP) scheme which jointly optimizes the allocation of channel code rates and number of repeats to image packets, subject to a constraint on the maximum overall transmission rate. The coding scheme used is the rate compatible punctured convolutional code coupled with the code‐combining technique. An unequal allocation of headers to the image packets is also performed in order to reduce the overall distortion due to error propagation. Simulation results show that the proposed UEP scheme provides a gain of more than 8 dB in peak‐to‐peak signal‐to‐noise ratio over a tandem scheme. The flexibility of the proposed scheme, and the major performance gains obtained, make the scheme appealing for applications like, web‐based image browsing, multi‐hop networks, and wireless image transmission. Copyright © 2007 John Wiley & Sons, Ltd.
Synthesis of a 24‐Membered Cyclic Peptide‐Biphenyl Hybrid
Authors: Montero Ana , Albericio Fernando , Royo Miriam , Herradón Bernardo 
Published: January 2007

AbstractThe synthesis of a 24‐membered macrocyclic peptide‐biphenyl hybrid with four amino acid residues and two biphenyl fragments was performed by a combination of solid‐phase and solution methodologies. The acyclic precursor was prepared by a solid phase methodology whereas the final macrocyclization was carried out by diisopropylcarbodiimide (DIPCDI) and N‐hydroxybenzotriazole (HOBt) in solution. The target molecule was a moderate inhibitor of μ‐calpain. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2007)
CuCl‐Catalyzed Regio‐ and Stereoselective Aminohalogenation of α,β‐Unsaturated Nitriles
Authors: Han Jian‐Lin , Zhi San‐Jun , Wang Le‐Yong , Pan Yi , Li Guigen 
Published: January 2007

Abstractα,β‐Unsaturated nitriles were found to be suitable substrates for aminochlorination with N,N‐dichloro‐p‐toluenesulfonamide (4‐TsNCl2) in the presence of CuCl as the catalyst (10 mol‐%) and 4 Å molecular sieves. The reaction is very convenient to carry out at room temperature without the protection of inert gases, and this method provides an easy route to vicinal haloamino nitriles with excellent regio‐ and stereoselectivities and in good chemical yields. The stereochemistry has been unambiguously confirmed by X‐ray structural analysis. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2007)
Comparison of air quality management strategies of PM10, SO2, and NOx by an industrial source complex model in Beijing
Authors: Ying Gaoxiang , Ma Jia , Xing Yi 
Published: January 2007

AbstractThe primary air pollutants in the Beijing urban area are fine particulate matter (PM10), sulfur dioxide (SO2), and nitrogen oxides (NOx). Using suitable emission factors for point, area, and line sources from 20 categories of industrial, commercial, domestic and traffic, total yearly mean emissions were estimated at 103.3 kton of PM10, 209.9 kton of SO2, and 225.4 kton of NOx in 1999. To abate this elevated air pollution, three air quality management schemes are adopted. After the implementation, the annual mean ground‐level concentrations of air pollutants are predicted by an industrial source complex short term (ISCST3) dispersion model and compared by the geographic information system (GIS). The ISCST3 dispersion model is used by inputting emission inventory and meteorological data with 1 h temporal and 1 km × 1 km spatial resolution. The model validity is verified by its agreement with monitoring data from Beijing's Environmental Protection Bureau. Results indicate that the levels of PM10, SO2, and NOx in Beijing are improved gradually because of the adoption of these three control schemes. The predicted annual mean concentrations decreased from 90.63 to 67.28 μg/m3 for PM10, 57.94 to 31.77 μg/m3 for SO2, and 119.97 to 73.83 μg/m3 for NOx, respectively. © 2007 American Institute of Chemical Engineers Environ Prog 26:33–42, 2007.
Quasi steady‐state method of catalyst evaluation for air pollution control
Authors: Berty József M. 
Published: January 2007

AbstractThe focus of this publication is on the methods used and evaluations applied for testing oxidation catalysts for air pollution control. The mathematical basis is first discussed then the effect of assumptions is evaluated, potential errors examined, finally possible manpower, and expense‐saving methods will be shown all on actual experimental results. The results of the examples are important, only to illustrate the techniques applied. Finally the use of a simple mathematical process will be presented to predict the performance of the catalyst to reach various commercial performance requirements. The presented method will benefit both who test catalyst in the laboratory and those who use the results to design pollution control units. © 2007 American Institute of Chemical Engineers Environ Prog 26:43–49, 2007.
Geranyl acetate esterase is commonly present but linalyl acetate esterase occurrence is highly limited in plants
Authors: Sangwan Neelam S. , Sharma Pankaj K. , Sangwan Rajender S. 
Published: January 2007

AbstractEsterases are a group of hydrolytic enzymes that split ester bonds by addition of water and are ubiquitously present in diverse biosystems. Although animal esterases are well studied and are catalytically and functionally classified into different groups, plant enzymes have been viewed rather generally and are casually recruited as biochemical markers in morphogenesis, genetic characterization of plants, etc., without functional emphasis. Some volatile oil plants constitutively synthesize their characteristic monoterpene esters, geranyl acetate and linalyl acetate being the most common among them in the acyclic monoterpene class, whereas other plants also synthesize some volatile hemi‐ to sesquiterpene esters but inductively under certain ecological situations, such as herbivory, wounding, etc. This study concerns screening relative distribution of geranyl acetate esterase and linalyl aceate esterase activities in selected medicinal and aromatic plants, and reveals that in plants geranyl acetate (a primary alcohol ester) esterase is commonly present, while linalyl acetate (a tertiary alcohol ester) esterase seems to be highly limited to those plants (e.g. Lippia alba, Mentha citrata) that biosynthesize the tertiary monoterpene alcohol linalool and its ester. Such contrasting distribution of the two discrete types of esterases has been discussed in light of scenario of their microbial counterparts and structure–function relationships established thereon. This study makes it obvious that the GGG(A)‐X motif esterases (acting on tertiary alcohol esters) are rare entities in plants too, similar to microbes. Furthermore, their presence in some volatile oil plants renders such plants novel phytoresources of the GGGX/GGAX motif hydrolases. Detailed characterization of the motif‐specific plant esterases would have an immense impact on understanding of their structure–function relationships in plants. Copyright © 2007 John Wiley & Sons, Ltd.
Components of the essential oil from sprouts of Polygonum hydropiper L. (‘Benitade’)
Authors: Miyazawa Mitsuo , Tamura Naotaka 
Published: January 2007

AbstractThe components of the essential oil from sprouts of Polygonum hydropiper L. (‘Benitade’) were analysed by capillary GC and GC–MS. Fifty‐three components were identified, representing 91.6% of the total oil. The main constituents of the essential oil were (E)‐β‐farnesene (44.1%), phytol (10.8%), (E)‐caryophyllene (9.3%), (E)‐nerolidol (6.9%). The essential oil from Benitade contained a high content of sesquiterpenoids. Copyright © 2007 John Wiley & Sons, Ltd.
Multifactor and analytical valuation of treasury bond futures with an embedded quality option
Authors: Nunes João Pedro Vidal , Oliveira Luís Alberto Ferreira De 
Published: January 2007

AbstractA closed‐form pricing solution is proposed for the quality option embedded in Treasury bond futures contracts, under a multifactor and D. Heath, R. Jarrow, and A. Morton (1992) Gaussian framework. Such an analytical solution can be obtained through a conditioning approximation, in the sense of M. Curran (1994) and L. Rogers and Z. Shi (1995), or via a rank 1 approximation, following A. Brace and M. Musiela (1994). Monte Carlo simulations show that both approximations are extremely accurate and easy to calculate.Application of the proposed pricing model to the EUREX market from January 2000 through May 2004, yields an excellent fit and an insignificant estimate of the quality option magnitude. On average, this delivery option accounts for only of the futures prices. © 2007 Wiley Periodicals, Inc. Jrl Fut Mark 27:275–303, 2007
Does high‐dose carmustine increase overall survival in supratentorial high‐grade malignant glioma? An EBMT retrospective study
Authors: Bay Jacques‐Olivier , Linassier Claude , Biron Pierre , Durando Xavier , Verrelle Pierre , Kwiatkowski Fabrice , Rosti Giovanni , Demirer Taner ,   for the EMBT solid tumors working party
Published: January 2007

AbstractRadiotherapy plus concomitant and adjuvant temozolomide have demonstrated improved survival for glioblastoma. However, prognosis remains poor. High‐doses chemotherapy with carmustine is another way to improve response and survival by increasing the dose delivered. Myelotoxicity imposes autologous stem cell rescue. European Group for Blood and Marrow Transplantation experience of this treatment in patients with high‐grade glioma was reported here. A retrospective analysis of 217 patients from European Group for Blood and Marrow Transplantation database was realized. Ninety‐six patients underwent complete surgical resection while the 121 others had partial resection or only biopsy and were evaluable for an antitumor effect. Patients received 800 mg/m2 of carmustine intravenously at least 1 month after neurosurgery. Forty‐eight to 72 hr after chemotherapy, 108 patients received autologous hematopoietic stem cells from bone marrow harvest and 109 patients autologous hematopoietic stem cells from peripheral blood. Radiotherapy was started approximately 40 days after transplantation. Ten deaths were related to the treatment. Of the 121 patients evaluable for tumor response, 64 (53%) presented an objective response. This protocol appear feasible, but with toxicity‐related mortality of 4.5%. Median overall survival was 20 months and median time to treatment failure was 7 months. Overall survival and time to treatment were correlated with age, quality of resection and histological subtypes. In glioblastoma multiforme, age and surgery quality appeared to be prognostic factors. Compared with Stupp et al.'s recent study, this study did not favor high‐dose carmustine for patients with glioblastoma multiforme with complete surgical resection. © 2007 Wiley‐Liss, Inc.