bluuebunny/crossref_metadata_2025_split huggingface dataset:
In-hospital mortality after prehospital endotracheal intubation versus alternative methods of airway management in trauma patients. A cohort study from the TraumaRegister DGU®
Authors: Weigeldt Moritz , Schulz-Drost Stefan , Stengel Dirk , Lefering Rolf , Treskatsch Sascha , Berger Christian ,   the TraumaRegister DGU
Published: March 2024

Abstract
Purpose
Prehospital airway management in trauma is a key component of care and is associated with particular risks. Endotracheal intubation (ETI) is the gold standard, while extraglottic airway devices (EGAs) are recommended alternatives. There is limited evidence comparing their effectiveness. In this retrospective analysis from the TraumaRegister DGU®, we compared ETI with EGA in prehospital airway management regarding in-hospital mortality in patients with trauma.

Methods
We included cases only from German hospitals with a minimum Abbreviated Injury Scale score ≥ 2 and age ≥ 16 years. All patients without prehospital airway protection were excluded. We performed a multivariate logistic regression to adjust with the outcome measure of hospital mortality.

Results
We included n = 10,408 cases of whom 92.5% received ETI and 7.5% EGA. The mean injury severity score was higher in the ETI group (28.8 ± 14.2) than in the EGA group (26.3 ± 14.2), and in-hospital mortality was comparable: ETI 33.0%; EGA 30.7% (27.5 to 33.9). After conducting logistic regression, the odds ratio for mortality in the ETI group was 1.091 (0.87 to 1.37). The standardized mortality ratio was 1.04 (1.01 to 1.07) in the ETI group and 1.1 (1.02 to 1.26) in the EGA group.

Conclusions
There was no significant difference in mortality rates between the use of ETI or EGA, or the ratio of expected versus observed mortality when using ETI.
Assessment of length-of-day and universal time predictions based on the results of the Second Earth Orientation Parameters Prediction Comparison Campaign
Authors: Śliwińska-Bronowicz Justyna , Kur Tomasz , Wińska Małgorzata , Dobslaw Henryk , Nastula Jolanta , Partyka Aleksander , Belda Santiago , Bizouard Christian , Boggs Dale , Bruni Sara , Chen Lue , Chin Mike , Dhar Sujata , Dill Robert , Ferrandiz Jose Manuel , Gou Junyang , Gross Richard , Guessoum Sonia , Han Songtao , Heinkelmann Robert , Irrgang Christopher , Kiani Shahvandi Mostafa , Li Jia , Ligas Marcin , Liu Lintao , Lu Weitao , Mayer Volker , Michalczak Maciej , Modiri Sadegh , Otten Michiel , Ratcliff Todd , Raut Shrishail , Saynisch-Wagner Jan , Schartner Matthias , Schoenemann Erik , Schuh Harald , Soja Benedikt , Su Xiaoqing , Thaller Daniela , Thomas Maik , Wang Guocheng , Wu Yuanwei , Xu Xueqing , Yang Xinyu , Zhao Xin , Zhou Zhijin 
Published: March 2024

AbstractPredicting Earth Orientation Parameters (EOP) is crucial for precise positioning and navigation both on the Earth’s surface and in space. In recent years, many approaches have been developed to forecast EOP, incorporating observed EOP as well as information on the effective angular momentum (EAM) derived from numerical models of the atmosphere, oceans, and land-surface dynamics. The Second Earth Orientation Parameters Prediction Comparison Campaign (2nd EOP PCC) aimed to comprehensively evaluate EOP forecasts from many international participants and identify the most promising prediction methodologies. This paper presents the validation results of predictions for universal time and length-of-day variations submitted during the 2nd EOP PCC, providing an assessment of their accuracy and reliability. We conduct a detailed evaluation of all valid forecasts using the IERS 14 C04 solution provided by the International Earth Rotation and Reference Systems Service (IERS) as a reference and mean absolute error as the quality measure. Our analysis demonstrates that approaches based on machine learning or the combination of least squares and autoregression, with the use of EAM information as an additional input, provide the highest prediction accuracy for both investigated parameters. Utilizing precise EAM data and forecasts emerges as a pivotal factor in enhancing forecasting accuracy. Although several methods show some potential to outperform the IERS forecasts, the current standard predictions disseminated by IERS are highly reliable and can be fully recommended for operational purposes.
Autoimmune encephalitis: what the radiologist needs to know
Authors: Sanvito Francesco , Pichiecchio Anna , Paoletti Matteo , Rebella Giacomo , Resaz Martina , Benedetti Luana , Massa Federico , Morbelli Silvia , Caverzasi Eduardo , Asteggiano Carlo , Businaro Pietro , Masciocchi Stefano , Castellan Lucio , Franciotta Diego , Gastaldi Matteo , Roccatagliata Luca 
Published: March 2024

AbstractAutoimmune encephalitis is a relatively novel nosological entity characterized by an immune-mediated damage of the central nervous system. While originally described as a paraneoplastic inflammatory phenomenon affecting limbic structures, numerous instances of non-paraneoplastic pathogenesis, as well as extra-limbic involvement, have been characterized. Given the wide spectrum of insidious clinical presentations ranging from cognitive impairment to psychiatric symptoms or seizures, it is crucial to raise awareness about this disease category. In fact, an early diagnosis can be dramatically beneficial for the prognosis both to achieve an early therapeutic intervention and to detect a potential underlying malignancy. In this scenario, the radiologist can be the first to pose the hypothesis of autoimmune encephalitis and refer the patient to a comprehensive diagnostic work-up – including clinical, serological, and neurophysiological assessments.In this article, we illustrate the main radiological characteristics of autoimmune encephalitis and its subtypes, including the typical limbic presentation, the features of extra-limbic involvement, and also peculiar imaging findings. In addition, we review the most relevant alternative diagnoses that should be considered, ranging from other encephalitides to neoplasms, vascular conditions, and post-seizure alterations. Finally, we discuss the most appropriate imaging diagnostic work-up, also proposing a suggested MRI protocol.
Optimal Control Related to Weak Solutions of a Chemotaxis-Consumption Model
Authors: Corrêa Vianna Filho André Luiz , Guillén-González Francisco 
Published: March 2024

AbstractIn the present work we investigate an optimal control problem related to the following chemotaxis-consumption model in a bounded domain $$\Omega \subset {\mathbb {R}}^3$$

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. We address the existence of optimal control restricted to a weak solution setting, where, in particular, uniqueness of state (u, v) given a control f is not clear. Then by considering weak solutions satisfying an adequate energy inequality, we prove the existence of optimal control subject to uniformly bounded controls. Finally, we discuss the relation between the considered control problem and two other related ones, where the existence of optimal solution can not be proved.
Ultrasound-guided initial diagnosis and follow-up of pediatric idiopathic intracranial hypertension
Authors: Kerscher Susanne Regina , Zipfel Julian , Haas-Lude Karin , Bevot Andrea , Schuhmann Martin Ulrich 
Published: March 2024

Abstract

Background
Idiopathic intracranial hypertension in children often presents with non-specific symptoms found in conditions such as hydrocephalus. For definite diagnosis, invasive intracranial pressure measurement is usually required. Ultrasound (US) of the optic nerve sheath diameter provides a non-invasive method to assess intracranial pressure. Transtemporal US allows imaging of the third ventricle and thus assessment for hydrocephalus.

Objective
To investigate whether the combination of US optic nerve sheath and third ventricle diameter can be used as a screening tool in pediatric idiopathic intracranial hypertension to indicate elevated intracranial pressure and exclude hydrocephalus as an underlying pathology. Further, to analyze whether both parameters can be used to monitor treatment outcome.

Materials and methods
We prospectively included 36 children with idiopathic intracranial hypertension and 32 controls. Using a 12-Mhz linear transducer and a 1–4-Mhz phased-array transducer, respectively, optic nerve sheath and third ventricle diameters were determined initially and during the course of treatment.

Results
In patients, the mean optic nerve sheath diameter was significantly larger (6.45±0.65 mm, controls: 4.96±0.32 mm) and the mean third ventricle diameter (1.69±0.65 mm, controls: 2.99±1.31 mm) was significantly smaller compared to the control group, P<0.001. Optimal cut-off values were 5.55 mm for the optic nerve sheath and 1.83 mm for the third ventricle diameter.

Conclusions
The combined use of US optic nerve sheath and third ventricle diameter is an ideal non-invasive screening tool in pediatric idiopathic intracranial hypertension to indicate elevated intracranial pressure while ruling out hydrocephalus. Treatment can effectively be monitored by repeated US, which also reliably indicates relapse.
Mechanical Purification of Lipofilling: The Relationship Between Cell Yield, Cell Growth, and Fat Volume Maintenance
Authors: Gentile Pietro , Ossanna Riccardo , Sierra Lindsey Alejandra Quintero , Sbarbati Andrea 
Published: March 2024

Abstract
Background
The mechanical manipulations of fat tissue represented from centrifugation, filtration, washing, and fragmentation were considered the most effective strategies aiming to obtain purified lipofilling with different impacts both in terms of adipose-derived stem cells amount contained in stromal vascular fraction, and fat volume maintenance.

Objectives
The present work aimed to report results in fat volume maintenance obtained by lipofilling purification based on the combined use of washing and filtration, in a clinical study, and to deeply investigate the adipose-derived stem cells yield and growth capacity of the different stromal vascular fraction extraction techniques with an in vitro approach.

Methods
A preliminary prospective, case-control study was conducted. 20 patients affected by face and breast soft tissue defects were treated with lipofilling and divided into two groups: n = 10 patients (study group) were treated with lipofilling obtained by washing and filtration procedures, while n = 10 (control group) were treated with lipofilling obtained by centrifugation according to the Coleman technique. 6 months after the lipofilling, the volume maintenance percentage was analyzed by clinical picture and magnetic resonance imaging comparisons. Additionally, extracted stromal vascular fraction cells were also in vitro analyzed in terms of adipose-derived stem cell yield and growth capacity.

Results
A 69% ± 5.0% maintenance of fat volume after 6 months was observed in the study group, compared with 44% ± 5.5% in the control group. Moreover, the cellular yield of the control group resulted in 267,000 ± 94,107 adipose-derived stem cells/mL, while the study group resulted in 528,895 ± 115,853 adipose-derived stem cells /mL, with a p-value = 0.1805. Interestingly, the study group showed a fold increase in cell growth of 6758 ± 0.7122, while the control group resulted in 3888 ± 0.3078, with a p < 0.05 (p = 0.0122).

Conclusions
The comparison of both groups indicated that washing and filtration were a better efficient system in lipofilling preparation, compared to centrifugation, both in terms of volume maintenance and adipose-derived stem cell growth ability.

Level of Evidence III
This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors http://www.springer.com/00266.
Fear of movement and competence frustration mediate the relationship between pain catastrophising and physical function in people living with axSpA: an online cross-sectional survey
Authors: Rouse Peter C. , Ingram Thomas , Standage Martyn , Sengupta Raj 
Published: March 2024

AbstractThe objective of this study is to examine the contribution of pain catastrophising to Axial Spondyloarthritis (axSpA) patient’s physical function and to test the mediating role of fear of movement, and uniquely, the contribution of competence frustration to the fear-avoidance model. Participants (N = 98, 70% female, M age = 45.62, SD 12.16) completed an online survey (December 2020–May 2021) distributed in the United Kingdom via the National Axial Spondyloarthritis Society (n ≈ 3500; NASS, 2019). The PROCESS SPSS macro was used to test three mediation models using percentile bootstrap 95% confidence intervals (PBCI). A significant indirect effect on the relationship between pain and physical function via fear of movement (β = 0.10, 95% PBCI = 0.030–0.183) was observed (Model 1). Model 2 showed the relationship between pain catastrophising and physical function to be significantly mediated by fear of movement (β = 0.16, 95% PBCI = 0.005–0.322). Finally, Model 3 showed a significant indirect effect on the relationship between pain catastrophising and physical function via competence frustration (β = 0.15, 95% PBCI = 0.014–0.309) but not through fear of movement (β = 0.062, 95% PBCI = − 0.134 to 0.248). To our knowledge, this is the first study to examine and demonstrate the unique contribution of competence need frustration to the Fear-avoidance model in people that live with axSpA. Identifying modifiable factors that contribute to disease outcomes such as physical function can improve the care and quality of life for people living with a disease currently without a cure.
Preoperative ultrasound-guided dual localization with titanium clips and carbon nanoparticles for predicting the surgical approach and guiding the resection of Siewert type II esophagogastric junction adenocarcinoma
Authors: Wu Weihang , Luo Ziqiang , Fang Yongchao , Yu Li , Lin Nan , Yang Jin , Zhao Hu , Xiao Chunhong , Wang Yu 
Published: March 2024

Abstract
Objective
To investigate the superiority of preoperative ultrasound-guided titanium clip and nanocarbon dual localization over traditional methods for determining the surgical approach and guiding resection of Siewert type II adenocarcinoma of the esophagogastric junction (AEG).

Method
This study included 66 patients with Siewert type II AEG who were treated at the PLA Joint Logistics Support Force 900th Hospital between September 1, 2021, and September 1, 2023. They were randomly divided into an experimental group (n = 33), in which resection was guided by the dual localization technique, and the routine group (n = 33), in which the localization technique was not used. Surgical approach predictions, proximal esophageal resection lengths, pathological features, and the occurrence of complications were compared between the groups.

Result
The use of the dual localization technique resulted in higher accuracy in predicting the surgical approach (96.8% vs. 75.9%, P = 0.02) and shorter proximal esophageal resection lengths (2.39 ± 0.28 cm vs. 2.86 ± 0.39 cm, P < 0.001) in the experimental group as compared to the routine group, while there was no significant difference in the incidence of postoperative complications (22.59% vs. 24.14%, P = 0.88).

Conclusion
Preoperative dual localization with titanium clips and carbon nanoparticles is significantly superior to traditional methods and can reliably delineate the actual infiltration boundaries of Siewert type II AEG, guide the surgical approach, and avoid excessive esophageal resection.
Evaluating rock mass groutability at shallow depths: a novel approach based on geo-structural surveys and permeability tests
Authors: De Luca C. , Pignalosa A. , Budetta Paolo 
Published: March 2024

AbstractThe study describes the geological and geo-structural setting of an unstable sea arch in a very attractive landscape of Southern Italy. It evaluates the applicability of some reinforcement work designs consisting of rock mass grouting at shallow depths along the arch vault and abutments. To this aim, the hydraulic conductivity of the rock mass and its groutability were evaluated in detail, integrating field geo-mechanical surveys, boreholes, Lugeon tests, and grouting tests with different grout compositions. Results from site tests were compared with grout take values calculated by applying classical empirical approaches available in the literature, based on rock mass permeability, or by using a novel deterministic approach based on geo-mechanical field surveys. Considering the shallow depths of the tests, the results suggest that the former gave high values, inconsistent with grout tests. On the contrary, the novel deterministic approach provided grout take values consistent with the results of grouting tests, resulting in the most reliable approach for the arch’s thin, shallow, and highly fractured structure.The use of different grout compositions in the site tests proved that extensive use of highly dense and viscous slurries is required (bentonite-cement grout) due to the high-grade weathering and karstification of joint surfaces, which deeply increases their hydraulic conductivity. However, the rock mass grouting must be considered complementary to other reinforcement measures such as bolting, especially along the arch vault.
Impacts of climate change on airborne Quercus pollen trends in Andalusia region (southern Spain)
Authors: Alcázar Purificación , Torres Carmen , De Linares Concepción , González-Minero Francisco José , Valenzuela Luis Ruiz , Picornell Antonio , Galán Carmen 
Published: March 2024

AbstractQuercus species are the most frequent autochthonous arboreal taxa in the natural areas of Andalusia region (southern Spain). Due to their abundance and anemophilous character, high airborne pollen concentrations are detected in natural and urban areas of the region. Variations in its reproductive phenology can be considered an important bio-indicator regarding the impacts of climate change on vegetation in the Mediterranean region. This study aims to analyze trends in flowering patterns using airborne pollen concentrations from the capital cities of the 8 provinces of Andalusia region and to study its relationships with meteorological parameters and climate change over decades. Variations in time and intensity of flowering have been studied using different methods for defining the pollen season. This study demonstrates that for comparing results, it is relevant to choose the right definition to calculate the pollen season. The analysis of historical databases of Quercus airborne pollen in Andalusia showed variations in the floral phenology with an increase in the intensity of the pollen season throughout the studied period and an advance in the start trends due to the increase of temperature. Nevertheless, this increase might have been smoothed by the decrease of precipitations in some sampler locations, a limiting factor in the area. It has been also observed a delay in the end dates that caused a lengthening of the season. Climate change could be provoking longer and more intense pollen seasons that will lead to more intense and persistent symptoms in sensitive patients.
A hybrid Gaussian mixture/DSMC approach to study the Fourier thermal problem
Authors: Mohammad Nejad Shahin , Peters Frank A. , Nedea Silvia V. , Frijns Arjan J. H. , Smeulders David M. J. 
Published: March 2024

AbstractIn rarefied gas dynamics scattering kernels deserve special attention since they contain all the essential information about the effects of physical and chemical properties of the gas–solid surface interface on the gas scattering process. However, to study the impact of the gas–surface interactions on the large-scale behavior of fluid flows, these scattering kernels need to be integrated in larger-scale models like Direct Simulation Monte Carlo (DSMC). In this work, the Gaussian mixture (GM) model, an unsupervised machine learning approach, is utilized to establish a scattering kernel for monoatomic (Ar) and diatomic ($$\hbox {H}_{2}$$H2) gases directly from Molecular Dynamics (MD) simulations data. The GM scattering kernel is coupled to a pure DSMC solver to study isothermal and non-isothermal rarefied gas flows in a system with two parallel walls. To fully examine the coupling mechanism between the GM scattering kernel and the DSMC approach, a one-to-one correspondence between MD and DSMC particles is considered here. Benchmarked by MD results, the performance of the GM-DSMC is assessed against the Cercignani–Lampis–Lord (CLL) kernel incorporated into DSMC simulation (CLL-DSMC). The comparison of various physical and stochastic parameters shows the better performance of the GM-DSMC approach. Especially for the diatomic system, the GM-DSMC outperforms the CLL-DSMC approach. The fundamental superiority of the GM-DSMC approach confirms its potential as a multi-scale simulation approach for accurately measuring flow field properties in systems with highly nonequilibrium conditions.
A comparative analysis of how to handle stockout scenarios: the impact of newsvendor’s risk attitude
Authors: Wood Doran , Çetinkaya Sıla 
Published: March 2024

AbstractThe purpose of this paper is to evaluate contrasting approaches for handling excess demand through the lens of a retailer (newsvendor) whose risk attitude (risk-neutral versus risk-averse) is modeled explicitly. We employ representative newsvendor models and provide comparison between two well-established stockout policies when demand exceeds supply. The “while supplies last” policy avoids the need for a secondary production order to satisfy the excess demand but faces potential opportunity cost through lost sales. Conversely, the “accepting backorders” policy relies on recourse production availability which is potentially costly but meets all levels of realized demand. Across distinct parameter classes, we incorporate comparison between the two policies in terms of financial metrics including expected profit and conditional value-at-risk criteria as well as metrics that relate to inventory availability and, hence, customer service, e.g., stockout probabilities and expected excess inventory. Powerful analytical results encompass both financial and inventory metrics and reveal that the outperforming policy is simply determined through relative underage cost values. That is, our insights indicate general advantages of accepting backorders when profit margins are sufficiently large and advantages of ignoring excess demand when profit margins are smaller. Although these extensive analytical takeaways hold in general, our numerical study reveals mean order quantity deviations (decision bias) in addition to which modeling approaches and counterpart optimal solutions maintain outperformance (resiliency) or lead to underperformance (sensitivity) when evaluated across all objective function criteria.