bluuebunny/crossref_metadata_2025_split huggingface dataset:
Occupational stress and musculoskeletal disorders in firefighters: the mediating effect of depression and job burnout
Authors: Khoshakhlagh Amir Hossein , Al Sulaie Saleh , Mirzahosseininejad Marziyeh , Yazdanirad Saeid , Orr Robin Marc , Laal Fereydoon , Bamel Umesh 
Published: February 2024

AbstractThe firefighting profession carries a heightened risk of musculoskeletal disorders. A firefighter’s job is physically demanding and includes activities such as running, climbing, dragging, and lifting. Often, these tasks are unpredictable, performed in harsh environments, and have been found to cause psychological stress. The purpose of this study was to investigate the effects of occupational stress on work-related musculoskeletal disorders (WRMSD) in firefighters. In addition, the mediating effects of depression and job burnout on proposed relationships were examined. Data informing this study were collected using a survey questionnaire. The survey questionnaire included the Beck Depression Inventory, the Center for Epidemiological Studies Depression Scale (CES-D), the Maslach Burnout Inventory, the Post Traumatic Stress Disorder Inventory (PCL), and the Nordic Musculoskeletal Questionnaire. Collected data were analyzed using structural equation modeling approach in AMOS. The results of the 2339 responding firefighters suggest that work related stress is positively related to WRMSDs in firefighters and can lead to musculoskeletal symptoms through four paths, being emotional exhaustion, personal accomplishment, CES-D total score, and depersonalization. Through depersonalization, job stress had the most significant impact on musculoskeletal symptoms (coefficient = 0.053). Furthermore, the results showed that post-traumatic stress disorders (PTSD) can affect musculoskeletal symptoms through ten paths, again through depersonalization, PTSD had the most significant impact on musculoskeletal symptoms (coefficient = 0.141). The results of this study suggest that organizations should design interventions and policies to prevent and manage occupational stress, depression, and job burnout to negate its undesired consequences on firefighters’ health (i.e. WRMSD).
Leveraging generative AI to prioritize drug repurposing candidates for Alzheimer’s disease with real-world clinical validation
Authors: Yan Chao , Grabowska Monika E. , Dickson Alyson L. , Li Bingshan , Wen Zhexing , Roden Dan M. , Michael Stein C. , Embí Peter J. , Peterson Josh F. , Feng QiPing , Malin Bradley A. , Wei Wei-Qi 
Published: February 2024

AbstractDrug repurposing represents an attractive alternative to the costly and time-consuming process of new drug development, particularly for serious, widespread conditions with limited effective treatments, such as Alzheimer’s disease (AD). Emerging generative artificial intelligence (GAI) technologies like ChatGPT offer the promise of expediting the review and summary of scientific knowledge. To examine the feasibility of using GAI for identifying drug repurposing candidates, we iteratively tasked ChatGPT with proposing the twenty most promising drugs for repurposing in AD, and tested the top ten for risk of incident AD in exposed and unexposed individuals over age 65 in two large clinical datasets: (1) Vanderbilt University Medical Center and (2) the All of Us Research Program. Among the candidates suggested by ChatGPT, metformin, simvastatin, and losartan were associated with lower AD risk in meta-analysis. These findings suggest GAI technologies can assimilate scientific insights from an extensive Internet-based search space, helping to prioritize drug repurposing candidates and facilitate the treatment of diseases.
Glycogen deficiency enhances carbon partitioning into glutamate for an alternative extracellular metabolic sink in cyanobacteria
Authors: Kato Yuichi , Hidese Ryota , Matsuda Mami , Ohbayashi Ryudo , Ashida Hiroki , Kondo Akihiko , Hasunuma Tomohisa 
Published: February 2024

AbstractGlycogen serves as a metabolic sink in cyanobacteria. Glycogen deficiency causes the extracellular release of distinctive metabolites such as pyruvate and 2-oxoglutarate upon nitrogen depletion; however, the mechanism has not been fully elucidated. This study aimed to elucidate the mechanism of carbon partitioning in glycogen-deficient cyanobacteria. Extracellular and intracellular metabolites in a glycogen-deficient ΔglgC mutant of Synechococcus elongatus PCC 7942 were comprehensively analyzed. In the presence of a nitrogen source, the ΔglgC mutant released extracellular glutamate rather than pyruvate and 2-oxoglutarate, whereas its intracellular glutamate level was lower than that in the wild-type strain. The de novo synthesis of glutamate increased in the ΔglgC mutant, suggesting that glycogen deficiency enhanced carbon partitioning into glutamate and extracellular excretion through an unidentified transport system. This study proposes a model in which glutamate serves as the prime extracellular metabolic sink alternative to glycogen when nitrogen is available.
Ethically Responsible Participant Selection in Research: A Viewpoint
Authors: Irizarry-Pérez Carlos D. , Fabiano Leah , Martinez-Fisher Andrea 
Published: February 2024

Purpose:
The American Speech-Language-Hearing Association (ASHA) has committed to advancing diversity, equity, and inclusion (DEI) in the profession of speech and hearing sciences. However, there exist significant discrepancies between the demographics of our members and the populations served. These discrepancies extend to the participants included within our research publications. This article addresses participant selection when conducting research investigations. First, we draw attention to standards of conduct that are present within and outside the field. Second, we highlight inequities that exist. We explore a case study as an example. Finally, we offer suggestions to help rectify the problem.

Conclusions:
Inequities at the level of participants' selection result in discrepant access to clinical services and evidence-based research for multilingual individuals; neurodiverse individuals; and Black, Indigenous, and people of color communities. ASHA and researchers alike can show commitment to DEI by addressing this problem from multiple approaches.
A pilot protection scheme based on high‐frequency transient current waveform similarity for AC lines connected to HVDC inverter station
Authors: Duan Jiandong , Song Wenqiang , Du Xiaotong , Zhao Yuhang 
Published: February 2024

AbstractAffected by inverter station commutation failure and fast control, line fault characteristics are obviously different from traditional AC transmission line fault characteristics. The existing protection methods for AC line connected to line commutated converter based high voltage DC (LCC‐HVDC) inverter station (ACLs) have the problems of complex setting, weak anti‐noise and high demand for data synchronization. This paper proposes a pilot protection scheme based on high‐frequency transient current waveform similarity. Firstly, with analyzing the fault traveling wave propagation process, the obvious differences are found in the transient current waveforms at both ends of the line when internal and external faults occur. Then the similarity of transient current waveforms is measured with the improved longest common similar subsequence (LCSS) method. And the weak high‐frequency current is extracted with the improved synchronous squeezed S‐transform (SST) method. Finally, a large number of power systems computer aided design (PSCAD) simulation results show that the proposed protection method does not require strict data synchronization, has strong anti‐noise performance, and is tolerant to the influence of abnormal point fluctuations.
Testing analytical methods to derive the cosmic-ray ionisation rate in cold regions via synthetic observations
Authors: Redaelli E. , Bovino S. , Lupi A. , Grassi T. , Gaete-Espinoza D. , Sabatini G. , Caselli P. 
Published: February 2024

Context. Cosmic rays (CRs) heavily impact the chemistry and physics of cold and dense star-forming regions. However, the characterisation of their ionisation rate continues to pose a challenge from the observational point of view.
Aims. In the past, a few analytical formulas have been proposed to infer the cosmic-ray ionisation rate, ζ2, from molecular line observations. These have been derived from the chemical kinetics of the involved species, but they have not yet been validated using synthetic data processed with a standard observative pipeline. In this work, we aim to bridge this gap.
Methods. We performed a radiative transfer on a set of three-dimensional magneto-hydrodynamical simulations of prestellar cores, exploring different initial ζ2, evolutionary stages, types of radiative transfer (for instance assuming local-thermodynamic-equilibrium conditions), and telescope responses. We then computed the column densities of the involved tracers to determine ζ2, employing a recently proposed method based on the detection of H2D+. We compared this approach with a previous method, based on more common tracers. Both approaches are commonly used.
Results. Our results confirm that the equation based on the detection of H2D+ accurately retrieves the actual ζ2 within a factor of two to three in the physical conditions explored in our tests. Since we have also explored a non-local thermodynamic equilibrium (non-LTE) radiative transfer, this work indirectly offers insights into the excitation temperatures of common transitions at moderate volume densities (n ≈ 105 cm−3). We also performed a few tests using a previous methodology that is independent of H2D+, which overestimates the actual ζ2 by at least two orders of magnitude. We considered a new derivation of this method, however, we found that it still leads to high over-estimations.
Conclusions. The method based on H2D+ is further validated in this work and demonstrates a reliable method for estimating ζ2 in cold and dense gas. On the contrary, the former analytical equation, as already pointed out by its authors, has no global domain of application. Thus, we find that it ought to be employed with caution.
Les mines : enjeu de la transition écologique ? Un colloque au centre à Paris de l’Université de Chicago
Authors: Halloy José , Vidal Florian 
Published: February 2024

Le colloque « Les mines : enjeu de la transition écologique ? » a été organisé par José Halloy et Florian Vidal, le 23 septembre 2021 au centre à Paris de l’Université de Chicago. L’objectif de cette demi-journée de discussions était d’initier une première rencontre interdisciplinaire sur la problématique minière à l’aune de la transition écologique et des changements globaux. Dans ce contexte, le débat autour des activités minières ouvre frontalement la question des ressources et du modèle sociotechnique de nos sociétés dans l’Anthropocène. C’est aussi le moment de réfléchir aux conditions de la recherche interdisciplinaire en France. Nous présentons dans ce compte rendu le contexte scientifique qui a stimulé ce colloque, l’apport des différentes interventions et les suites à donner à ces échanges.
Liebe Leserinnen, liebe Leser…
Authors: Heinrich Michael 
Published: February 2024

Phytotherapie 2024 und die digitalisierte Globalisierung
„Die Phytotherapie in Deutschland, der Schweiz und Österreich
steht 2024 vor anhaltenden Herausforderungen wie begrenzter Integration in die
konventionelle Medizin, unzureichender wissenschaftlicher Anerkennung und
regulatorischer Komplexität. Die Standardisierung von pflanzlichen
Präparaten und die Förderung von Forschung bleiben
Schlüsselthemen. Überwindung von Akzeptanzbarrieren und
Sensibilisierung für die Vorteile pflanzlicher Heilmethoden sind
weiterhin erforderlich, um die Phytotherapie als etablierte und respektierte
Heilpraxis zu stärken“.
Atypische Schwellung des medialen Augenwinkels: Fallbericht von einem invertierten Papillom des Tränenapparats und Literaturrecherche
Authors: Molteni Gabriele , Laura Elisa , Ronzani Guglielmo , Sacchetto Andrea , Marchioni Daniele 
Published: February 2024

Zusammenfassung
Hintergrund Ein invertiertes Papillom (IP) des Tränenapparats ist eine seltene Erkrankung, und heutzutage gehen keine Risikofaktoren aus der Literatur hervor.
Anamnese Nach einem chemischen Trauma entwickelte sich eine schmerzlose, wachsende mediale Lidschwellung, begleitet von Epiphora.
Befund Endoskopie, Computertomografie und Magnetresonanztomografie wiesen eine definierte Läsion im linken Fossa Lacrimalis aus, die sich bis zum Tränenweg erstreckte.
Therapie Der Patient unterzog sich einem endoskopischen Eingriff mit einer Dakryozystorhinostomie.
Schlussfolgerung Der hier berichtete Fallbericht zeigt eine atypische Lokalisation eines weltbekannten Tumors mit einem verdächtigen Risikofaktor, damit jeder HNO ein IP des Tränenapparats unter irgendwelchen Anschwellungen der lateralen Nasenwand ins Auge fasst.
Retrospective evaluation of interventional radiological treatments for chronic mesenteric ischemia in Germany based on a four-year period of the DeGIR Registry: comparison of outcomes with international quality standards
Authors: Bastian Moritz B. , Wessendorf Joel , Scheschenja Michael , König Alexander Marc , Nadjiri Jonathan , Mahnken Andreas H. 
Published: February 2024

Purpose Endovascular treatment has emerged as the gold standard for managing chronic mesenteric ischemia (CMI) resulting from arterial stenosis or occlusion. This study aimed to assess the efficacy and complication rates of continuous interventional radiology treatment for CMI in Germany between 2018 and 2021, comparing these findings with international quality standards.
Materials and Methods Data for CMI therapy with stenting and percutaneous transluminal angioplasty (PTA) was obtained from the quality management system of the German Interventional Radiological Society (DeGIR). A total of 3752 endovascular procedures for CMI performed from 2018 to 2021 were documented (PTA: n = 675; stenting: n = 3077). Data was analyzed for technical and clinical success rates, as well as major complication rates.
Results Overall technical and clinical success rates for PTA and stenting procedures were 92.03 %/85.9 % and 98.76 %/96.62 %, respectively. The most common major complications were: arterial occlusion (PTA: 0.73 %; stenting: 0.63), major bleeding (PTA: 1.05 %; stenting: 0.68 %), aneurysm formation (PTA: 0.29 %; stenting: 0.72 %), stent dislodgment (PTA: 0 %; stenting: 0.06 %), and organ failure (PTA: 0.43 %; stenting: 0.96 %). Technical and clinical success rates were higher, while complication rates were lower than the corresponding threshold recommended by the Society of Interventional Radiology for the percutaneous management of chronic mesenteric ischemia.
Conclusion Treatment of CMI performed by interventional radiologists in Germany is safe and effective during daily and on-call shifts with results exceeding internationally accepted standards.
Key Points
Citation Format
Cannabinoide Arzneimittel bei Krebspatient*innen
Authors: Herdegen Thomas 
Published: February 2024

ZusammenfassungMedikamente, die die therapeutisch relevanten Inhaltsstoffe des Cannabis,
Tetrahydrocannabinol (THC) und Cannabidiol (CBD), enthalten, kommen bei
Krebspatient*innen zum Einsatz, um zum Beispiel Krankheitssymptome wie Schmerzen
oder Nebenwirkungen der Therapien zu lindern sowie die Lebensqualität zu
verbessern. Die Studienlage rechtfertigt die Anwendung von cannabinoiden
Arzneimitteln als Add-on-Therapie bei einem Total-Pain-Syndrom sowie Übelkeit,
Appetitlosigkeit, Schlaflosigkeit, erhöhtem Muskeltonus, Stress, depressiven
Verstimmungen, Ängstlichkeit und fehlender Distanzierung zum
Krankheitsgeschehen. Erste Hinweise deuten zudem auf eine mögliche
Anti-Tumor-Wirkung dieser Arzneimittel hin.
Impact of Congenital Heart Disease on the Outcomes of Very Low Birth Weight Infants
Authors: Chen Xuxin , Bhombal Shazia , Kwiatkowski David M. , Ma Michael , Chock Valerie Y. 
Published: February 2024

Objective This study aimed to investigate the association of congenital heart disease (CHD) with morbidity and mortality of very low birth weight (VLBW) infants.
Study Design This matched case–control study included VLBW infants born at a single institution between 2001 and 2015. The primary outcome was mortality. Secondary outcomes included necrotizing enterocolitis, bronchopulmonary dysplasia (BPD), sepsis, retinopathy of prematurity, and intraventricular hemorrhage. These outcomes were assessed by comparing VLBW-CHDs with control VLBW infants matched by gestational age within a week, birth weight within 500 g, sex, and birth date within a year using conditional logistic regression. Multivariable logistic regression analyzed differences in outcomes in the VLBW-CHD group between two birth periods (2001–2008 and 2009–2015) to account for changes in practice.
Results In a cohort of 44 CHD infants matched with 88 controls, the mortality rate was 27% in infants with CHD and 1% in controls (p < 0.0001). The VLBW-CHDs had increased BPD; (odds ratio [OR]: 7.70, 95% confidence interval [CI]: 1.96–30.29) and sepsis (OR: 10.59, 95% CI: 2.99–37.57) compared with the control VLBWs. When adjusted for preoperative ventilator use, the VLBW-CHDs still had significantly higher odds of BPD (OR: 6.97, 95% CI: 1.73–28.04). VLBW-CHDs also had significantly higher odds of both presumed and culture-positive sepsis as well as late-onset sepsis than their matched controls. There were no significant differences in outcomes between the two birth periods.
Conclusion VLBW-CHDs showed higher odds of BPD, sepsis, and mortality than VLBW infants without CHD. Future research should focus on the increased mortality and specific complications encountered by VLBW infants with CHD and implement targeted strategies to address these risks.
Key Points
COBRAs and virality: viral campaign values on consumer behaviour
Authors: Dinh Thi Cam Tu , Lee Yoonjae 
Published: February 2024

AbstractIn the digital marketing era, a viral brand campaign is a potent marketing tool for a brand, enabling it to derive multiple benefits through rapid and widespread information diffusion. Despite the important role of brand viral campaigns, existing studies have minimally explored the effect of viral campaign values on consumer behaviours, especially on a set of consumers’ online brand-related activities (COBRAs). Therefore, this study bridges this gap by proposing a detailed framework to measure the impact of viral campaigns on COBRAs through the aspects of medium, content, and interaction. To investigate this phenomenon, a survey was conducted with 409 respondents from the US, employing partial least-squares structural equation modelling (PLS-SEM). The findings reveal that six values of brand viral campaigns, including ease of browsing, hedonic value, functional value, aesthetic value, social interaction, and self-identity, significantly motivate consumers to actively engage in COBRAs. By examining COBRAs’ motivations in the viral brand campaign context, this study expands the existing literature with a comprehensive model of campaign values. Furthermore, by elucidating the impact of each campaign value on COBRAs, this study offers valuable insights to marketers and suggests effective strategies to engage consumers with brands.
Mapping of American English vocabulary by grade levels
Authors: Flor Michael , Holtzman Steven , Deane Paul , Bejar Isaac 
Published: February 2024

Abstract
We describe a large-scale effort to map English-language vocabulary by U.S. school grade levels. Our motivation is
to rapidly expand graded vocabulary resources for work with native English speakers in the USA, while taking into consideration
school-related influences rather than relying on just the corpus-frequency approaches. We report on the initial effort of data
collection, with mapping of about 22K word forms. We provide comparisons of this mapping to some other recent vocabulary mapping
efforts, such as age-of-acquisition. We then describe the efforts to automatically expand this resource by using linguistically
motivated variables and corpus-based methods. Our current resource maps more than 126K English word forms to US school grade
levels. We also compare a subset of our L1 mapped data to English L2 vocabulary levels, as expressed on the CEFR scale, and find
that there is a considerable overlap in the order of vocabulary learning in L1 and L2 English.
Swedish word family resource
Authors: Volodina Elena , Mohammed Yousuf Ali , Tiedemann Therese Lindström 
Published: February 2024

Abstract
The article introduces a novel lexical resource for Swedish based on word family principles. The development of
the Swedish Word Family (SweWF) resource is set into the context of linguistic complexity in second language acquisition. The
SweWF is particularly appropriate for that, given that it contains lexical items used in second language corpora, namely, in a
corpus of coursebook texts, and in a corpus of learner essays. The main focus of the article is on the construction of the
resource with its user interface and on its applicability for research, although it also opens vast possibilities for practical
applications for language learning, testing and assessment. We demonstrate the value of the resource through several case
studies.
Interests convergence in global human rights politics
Authors: Kim Yooneui 
Published: February 2024

Abstract
What explains the convergence and divergence of states’ interests related to global human rights? This study
examines the dyadic similarity of the language used in the multilateral dialogue focusing on the role of non-governmental
organizations (NGOs) and intergovernmental organizations (IGOs). The joint activities of NGOs influence states, and human rights
norms are transmitted through IGOs. Using text analysis methods, the similarity between state recommendations during the Universal
Periodic Review (UPR) process at the United Nations Human Rights Council (UNHRC) is systematically quantified. Analyses suggest
that a pair of states are more likely to use similar language in UPR recommendations as the number of joint activities of NGOs,
shared memberships in IGOs, and shared experience in the UNHRC increases. The effects are robust even after controlling for
different types of political relationships between states.
Revisiting loop quantum gravity with selfdual variables: Hilbert space and first reality condition
Authors: Sahlmann Hanno , Seeger Robert 
Published: February 2024

Abstract
We consider the quantization of gravity as an

S
L

(
2
,

C

)

gauge theory in terms of Ashtekar’s selfdual variables and reality conditions for the spatial metric (RCI) and its evolution (RCII). We start from a holomorphic phase space formulation. It is then natural to push for a quantization in terms of holomorphic wave functions. Thus we consider holomorphic cylindrical wave functions over

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L

(
2
,

C

)

connections. We use an overall phase ambiguity of the complex selfdual action to obtain Poisson brackets that mirror those of the real theory. We then show that there is a representation of the corresponding canonical commutation relations in the space of holomorphic cylindrical functions. We describe a class of cylindrically consistent measures that implements RCI. We show that spin networks with

S
U

(
2
)

intertwiners form a basis for gauge invariant states. They are still mutually orthogonal, but the normalisation is different than for the Ashtekar–Lewandowski measure for

S
U

(
2
)

. We do not consider RCII in the present article. Work on RCII is ongoing and will be presented elsewhere.