bluuebunny/crossref_metadata_2025_split huggingface dataset:
In Vitro Assessment of the Anti-Proliferative and Anti-Viability Effects of Salivary Gland Extracts from Hyalomma ticks (Acari: Ixodidae) on Human Colorectal Cancer Cells
Authors: Tavassoli Maryam , Kadivar Mehdi , Akhavan Amir Ahmad , Abdigoudarzi Mohammad , Moridnia Abbas , Chaibakhsh Samira , Beikmohammadi Mojtaba , Sedaghat Mohammad Mehdi 
Published: April 2024

Background: The saliva and salivary glands of ticks possess a wide range of immuno-pharmacologically active mole­cules that effectively modulate the activity of enzymes, antibodies, and amines that have a role in different biological processes. Derived components from saliva and salivary glands of hard ticks Ixodidae have been characterized as poten­tial natural sources for discovering promising anti-cancer drug candidates.
Methods: The anti-cancer activity of salivary gland extracts (SGEs) from Hyalomma anatolicum, Hyalomma drome­darii, Hyalomma marginatum, and Hyalomma schulzei was assessed. MTT assays and flow cytometry were done on the HT-29 colorectal cancer cell line to evaluate the anti-viability and proliferative inhibition.
Results: Based on the MTT assay results, the SGEs from Hy. dromedarii had the highest and lowest substantial anti-viability effects on the HT-29 cancer cell and human foreskin fibroblast (HFF) normal cell, respectively. The cytometric assessment revealed a significant increase in the apoptosis and necrosis ratio of the HT-29 cancer cells after treatment with Hy. dromedarii SGEs.
Conclusion: The results demonstrated that Hy. dromedarii SGEs have significant anti-proliferative, anti-viability, and apoptotic potential. The result of this study suggests that Hy. dromedarii SGEs is an appropriate candidate for further investigations to identify and purify the mechanisms and molecules involved in the anti-cancer activity of the SGEs.
TERAPI PSIKOPROBLEM MELALUI SHALAT DALAM MENJAWAB PERMASALAHAN MASYARAKAT MODERN
Authors: Rahman Etty setiawati 
Published: April 2024

Abstrack: The problems that humans face from time to time are increasingly complex, both problems related to their personal, family, work and life problems in general that lead to psychological problems. Therefore, these problems require treatment or therapy in overcoming them. The focus of this research is how prayer is able to overcome psychoproblems. The research method used is library research. So that in answering the problems above, the researchers collected data using a search for books that support the analysis. And the data collected was analyzed using descriptive analysis method using inductive analysis and deductive analysis. The result of this study indicated that prayer performated with humanity that is with tuma’ninah, tafakkur and tadabbur will provide healing and preventation as well as protection against psychoproblems. Where all readings and movements in prayer contain elements of therapy that can provide peace in the soul.

Keywords: Psychoproblem, Pray Therapy, Modern Society

Abstrak: Persoalan yang manusia hadapi dari waktu-kewaktu semakin kompleks, baik persoalan yang berhubungan dengan pribadinya, keluarganya, pekerjaan serta masalah kehidupan secara umum yang berujung pada permasalahan psikis. Oleh karena itu permasalahan tersebut membutuhkan pengobatan atau terapi dalam mengatasinya. Fokus penelitian ini adalah bagaimana shalat mampu dalam mengatasi psikoproblem. Metode penelitian yang digunakan adalah penelitian kepustakaan (library research). Sehingga dalam menjawab permasalahan-permasalahan di atas, maka peneliti melakukan pengumpulan data menggunakan penelusuran buku-buku yang yang mendukung analisis. Dan data yang terkumpul dianalisis menggunakan metode deskriptif analisa dengan menggunakan analisa induktif dan analisa deduktif. Hasil penelitian ini menunjukkan bahwa shalat yang dilakukan dengan khusyu’ yakni dengan tuma’ninah, tafakkur dan tadabbur akan memberikan penyembuhan dan pencegahan serta proteksi terhadap psikoproblem. Dimana semua bacaan dan gerakan dalam shalat mengandung unsur terapi yang dapat memberikan ketenangan dalam jiwa.

Kata Kunci: Psikoproblem, Terapi Shalat, Masyarakat Modern
“KOMUNIKASI ORGANISASI DALAM PEMBINAAN SKILL MAHASISWA MELALUI PERGERAKAN MAHASISWA ISLAM INDONESIA (PMII) RAYON AL-GHAZALI KOMISARIAT UNIVERSITAS ISLAM NEGERI (UIN) MATARAM”
Authors: Irhamdi Muhamad , Jayadi Herman 
Published: April 2024

Penelitian ini dilatarbelakangi oleh minimnya pembinaan skill di Universitas Islam Negeri (UIN) Mataram yang titik fokus penilitian berfokus kepada mahasiswa yg berorganisasikan Pergerakan Mahasiswa Islam Indonesia (PMII). Penelitian ini bertujuan untuk mengetahui apa saja bentuk pembinaan skill di kalangan mahasiswa yang berorganisasikan PMII dan bagaimana peran organisasi itu sendiri didalam kampus dan kalangan mahasiswa. Penelitian ini merupakan penilitian kualitatif yang mengangkat latar belakang permasalahan di organisasi Pergerakan Mahasiswa Islam Indonesia (PMII) Komisariat UIN mataram. Pengumpulan data dilakukan dengan wawancara, observasi, dan dokumentasi. Penilitian ini juga menggunakan metode kedekatan secara emotional kepada responden yang menjadi sumber data dalam penelitian. Adapun hasil penelitian yang di laksanakan oleh peneliti adalah: 1. pelaksanaaan kegiatan pelatihan dan pembinaan skill dalam organisasi PMII, caranya antara lain: a). jurnalis seperti pelatihan pembuatan cerpen, karya tulis ilmiah, pelatihan pembuatan bulletin, MC, tilawah, dan ngehost. Pelatihan-pelatihan ini dilakukan untuk pembinaan dalam meningkatkan skill para anggota rayon al-ghazali, komisariat universitas islam negeri mataram. 2. peran Organisasi PMII dalam meningkatkan skill pada kalangan mahasiswa. Adapun kendala yang ditemukan dilokasi dalam pelaksaan kegiatan pelatihan dan pembinaan skil, antara lain: a). ketidak konsisten kader dalam mengikuti pelatihan-pelatihan yang diadakan oleh pengurus rayon, b). kurangnya kesadaran kader dalam membangun potensi yang ada di dalam dirinya
DAKWAH KENABIAN DAN KONSTRUKSI MASYARAKAT KHAYALAN
Authors: HARYANTO ISHAK 
Published: April 2024

Abstract
The journey of the Prophet's da'wah as an arena to build a humanitarian system that is mutually acceptable and recognizes the values ??of human equality in the social system is still a deviation, even though life must embrace each other, accept unconditionally and respect human values. Acceptance between human beings seems to have become a deviation and even become a collective amnesia in social life. This collective amnesia is present in human life without realizing that we live in it so that acceptance for humans as a form of hablumminannas is like the construction of an imaginary society. The construction of an imaginary society had occurred in Medina as a social institution in the journey of prophetic da'wah. This happens as a living system process; a process of building its identity as a social system in building the ideal society that ever existed on this earth. The Medina community is a society based on a collective agreement that is contained in a charter, commonly known as the Medina charter, written above the interests of all groups, so that it can become a radical turning point for civilization to completely overhaul the values, symbols, and structures of society that have become acute. The Medina community is a society that results from a completely new social order so that it becomes a normal community identity. Be a role model when compared to neighboring areas at that time. Relationships between groups are built based on the breath of acceptance between others, because of the awareness of the similarity of nature and dignity as human beings. Why Medina is called the identity of a normal social system, none other than because of intersubjectivity; Human acceptance that is built from all components of the social system is always in communication and mutual acceptance.
PERANAN BAZNAS SEBAGAI STRATEGI DAKWAH DALAM PEMBERDAYAAN EKONOMI MASYARAKAT DI KABUPATEN LOMBOK BARAT
Authors: Masyhur Mashur 
Published: April 2024

Salah satu dari rukun Islam yang wajib ditunaikan setiap individu kaum muslim yakni menunaikan kewajiban zakat. Badan Amil Zakat Nasional (Baznas) berwenang melaksanakan tugas pengelolaan zakat secara nasional. Kewenangan ini menjadikan, keberadaan institusi zakat seperti, cukup efektif mengelola, menghimpun dan menyalurkan dana zakat kepada yang berhak menerima dalam berbagai bentuk. Metode penelitian yang digunakan ialah metode kualitafif. Hasil dari penelitian ini menunjukkan bahwa melalui program-program yang dilaksanakan, menyangkut berbagai jenis bantuan dan distribusi dana zakat, Baznas di kabupaten Lombok Barat, berperan sebagai media dakwah untuk mensyiarkan doktrin Islam di bidang sosial ekonomi, khususnya terkait gerakan-gerakan pemberdayaan ekonomi masyarakat yang melibatkan kelompok masyarakat kurang mampu, pedagang dan pelaku usaha yang membutuhkan bantuan modal serta yang lainnya.
STRATEGI PEMASARAN PRODUK PEMBIAYAAN MURABAHAH BSI (BANK SYARIAH INDONESIA) DI MEDAN TEMBUNG SUMATERA UTARA
Authors: Nadia Cahaya Amanda  , Muhammad Zen  
Published: April 2024

Abstract: Tujuan penelitian ini diteliti untuk mengetahui strategi pemasaran yang diterapkan oleh Bank Syariah Indonesia dalam memasarkan produk pembiayaan murabahahnya Adapun sumber data yang digunakan melaui observasi, interview dan dokumentasi serta referensi dari jurnal. Hasil penelitian ini menunjukkan bahwasannya Bank Syariah Indonesia (BSI) Medan Tembung menggunakan strategi pemasaran 4P (place. product, price dan promotion). Strategi yang sering digunakan yaitu pemasaran produk dibandingkan dari ketiga strategi lainnya. Melalui strategi produk, nasabah akan mengetahui kelebihan serta kekurangan produk pembiayaan murabahah. Strategi pemasaran produk lebih menarik untuk memikat nasabah agar menggunakan produk-produk yang ditawarkan dari Bank Syariah Indonesia (BSI)

Kata kunci: Strategi, Pemasaran, Produk, Pembiayaan Murabahah, BSI.
Islam Rahmatan Lil Alamin: Resolusi Dakwah Moderasi Beragama Ditengah Arus Globalisasi
Authors: Abdul Asis Ibrahim Abdul Asis Ibrahim 
Published: April 2024

Islam merupakan agama yang universal dan relevan dengan segala perkembangan zaman, yang hadir untuk membawa kabar gembira tentang kedamaian, keselamatan, dan kebahagiaan bagi seluruh umat manusia yang mengikuti ajarannya, Islam tidak mengajarkan sesuatu hal yang bersifat kehancuran, kejahatan, maupun kerusakan. Globalisasi merupakan penyatuan gerakan untuk menghubungkan semua negara dan bangsa, sehingga tidak ada dikotomi antara ajaran Islam dan globalisasi, sedangkan dakwah moderasi agama merupakan sebuah resolusi sebagai langkah strategis umat muslim untuk menyatakan dan menguatkan bahwa Islam adalah ajaran agama yang bersifat rahmatan lil alamin.
Kata Kunci: Islam Rahmatan Lil Alamin, Globalisasi, Dakwah Moderasi Beragama
Students' perspectives of a hybrid learning system in Kazakhstani higher education: A case study
Authors: Amirova Amina , Zhumabayeva Aziya , Zhunusbekova Aziza , Arenova Assyl , Nygymanova Nurbanu 
Published: April 2024

Hybrid learning is a relatively new approach in Kazakhstan's educational system. The transition to a new format necessitates a significant amount of effort and restructuring at the universities. The problems of researching the advantages and disadvantages of implementing this kind of instruction in the classroom are very relevant. The study's goal was to investigate students' attitudes towards implementing a hybrid learning environment. A qualitative method of data analysis was applied in the study. 1,186 students participated in hybrid learning at various universities in Kazakhstan. According to the findings, students value the flexibility and convenience of attending classes remotely through a two-way video conference. However, the findings also indicate that this new learning environment faces several pedagogical and technological challenges. These findings emphasize the importance of assisting students in understanding hybrid learning resources and goals thereby creating opportunities for success in hybrid learning. Policymakers in education can use it as a guide to develop policies related to crisis management or inclusive education as well as curriculum documents and resources for hybrid learning.
A metric for drinking water service reservoir performance as a sink or source of material
Authors: Kennedy (Doronina) Anastasia , Husband Stewart , Boxall Joby , Speight Vanessa 
Published: April 2024

ABSTRACT

Service reservoirs (SRs) are a critical component of drinking water distribution systems that impact water quality. There are no performance measures to quantify or understand this impact. By applying the concept of sink or source behaviour to describe the processes of material accumulation and mobilisation within SRs, this research develops a practical metric to facilitate assessment and quantification of SR performance. It is demonstrated how a few weeks of continuous data from instrumentation deployment at both inlet and outlet of SRs is sufficient to reveal valuable insight into SR and network performance. Through real-world applications, we provide evidence that the metric was able to track SR performance showing both beneficial and detrimental impacts on water quality, as well as quantifying seasonality and the benefits of SR cleaning. Such insight is invaluable for proactive, justifiable, and targeted decisions on the location and frequency of maintenance and management interventions.
Advances in aeration and wastewater treatment in shrimp farming: emerging trends, current challenges, and future perspectives
Authors: Tien Nguyen Nhut , Tran-Nguyen Phuong Lan , Vo Tran Thi Bich Chau 
Published: April 2024

ABSTRACT

The shrimp aquaculture industry has recently witnessed dramatic growth. Shrimp farming has gradually shifted from extensive to intensive or super-intensive models. However, the intensification of shrimp aquaculture is associated with energy security and environmental issues. The aeration system requires high energy demand to run mechanical aerators to maintain dissolved oxygen concentration in cultured ponds. Besides, intensive shrimp farms usually produce wastewater with high pollutant concentrations that may jeopardize the ecosystem when discharged. In an attempt to minimize the impacts of these problems, rigorous technological approaches have been carried out. This review provides recent advanced technologies employed to improve aeration and wastewater management. Moreover, this paper also introduces a sustainable energy model being studied and developed for aeration and wastewater treatment at shrimp farms.
Sol-gel synthesis of composite adsorbent coating from Prosopis juliflora–activated carbon for simultaneous adsorptive removal of Cd2+ and Cr2O72- from wastewater
Authors: Chintokoma Gilbert Chifundo , Chebude Yonas , Kassahun Shimelis Kebede , Demesa Abayneh Getachew , Koiranen Tuomas 
Published: April 2024

ABSTRACT

To overcome the challenges associated with powdered activated carbon (PAC) in water and wastewater treatment, the efficacy of composite adsorbent coating (CAC) synthesized using a simple sol-gel method with Prosopis juliflora-activated carbon for the simultaneous reduction of Cd2+ and Cr2O72− was investigated. The CAC was characterized by FTIR (C-H, C = O, and O-H stretching), pHPZC (6 -6.6), SEM (porous-rough surface), and BET surface area (10.6 m2/g) techniques. Statistical analysis confirmed that pH and contact time significantly (p &lt; 0.0001) affected both metal ions removal, with Cd2+ removal generally exceeding that of Cr2O72− due to better ionic properties. Using the optimized conditions (8.5 pH, 0.25 dosage, 5 mg concentration, 105 minutes contact time and 23.73 °C temperature), the predicted and experimental ion removal efficiencies were 86.86 and 83.98% for Cd2+ and 94.26 and 58.08% for Cr2O72−, respectively. The Langmuir adsorption isotherm was the best-suited model (R2 &gt; 0.99), while the metal ions removal was regulated by the PSO kinetic model (R2 &gt; 0.999). The adsorption process was endothermic and spontaneous, as indicated by thermodynamic values (−ΔG°, +ΔH°, +ΔS°). The study demonstrates CAC's effectiveness as an alternative to PAC, offering significant advantages in removing metal ions from wastewater.
Effects of climate change on streamflow in the Dez Basin of Iran using the IHACRES model based on the CMIP6 model
Authors: Goodarzi Mohammad Reza , Abedi Mohammad Javad , Niazkar Majid 
Published: April 2024

ABSTRACT
Understanding the changes in river flow is an important prerequisite for designing hydraulic structures as well as managing surface water resources in basins. By using the LARS-WG statistical downscaling model, the outputs of the general circulation model of the sixth report, including the ACCESS-ESM1 and BCC-CSM-MR models, under the SSP5.8.5 and SSP2.4.5 release scenarios. A more accurate spatial scale and daily precipitation and temperature time series were obtained for the studied area during the period of 2015–2043. Then the Identification of unit Hydrographs And Component flows from Rainfall, Evaporation and Streamflow data (IHACRES) rainfall-runoff model was calibrated in the study area. Based on the fit statistics in the calibration and validation stages, the overall performance of the developed model was evaluated as satisfactory. The calibrated hydrological model was driven by rainfall data and reduced air temperature to predict the effect of climate change on the output of the studied basin. The study showed that the studied basin has more rainfall (on average, 20.8% in the ACCESS-ESM1 model and 33.2% in the BCC-CSM2-MR model). The flow rate of the main river in the ACCESS-ESM1 model will decrease by 15% compared to the base period, and in the BCC-CSM2-MR model, it will increase by 16% compared to the base period.
Identification of COVID-19–Associated Hepatitis in Children as an Emerging Complication in the Wake of SARS-CoV-2 Infections: Ambispective Observational Study
Authors: Rawat Sumit Kumar , Asati Ajit Anand , Mishra Nitu , Jain Ashish , Ratho Radha Kanta 
Published: April 2024

Abstract

Background
Although the pediatric population has largely remained free of severe COVID-19 symptoms, in some cases, SARS-CoV-2 infection has been associated with complications such as multiple inflammatory syndrome in children (MIS-C). We identified another a unique form of hepatitis occurring subsequent to asymptomatic SARS-CoV-2 infection, designated by us as COVID-19–associated hepatitis in children (CAH-C), in a subset of children who presented with hepatitis.

Objective
Our study describes the clinical presentations, temporal association, and viral parameters of the CAH-C cases and compares them to those of MIS-C cases or other known forms of hepatitis in children.

Methods
In an ambispective (retrospective and follow-up) observational study, records from April to July 2021 were reviewed for all children aged ≤14 years who were previously healthy and presented with a sudden onset of hepatitis, elevated transaminases, and nonobstructive jaundice. After performing all routine tests, those lacking marked inflammatory responses and without evidence of (1) other known causes of acute hepatitis or previous underlying liver disease and (2) multisystem involvement were classified as having CAH-C. Their characteristics were compared to those of children with MIS-C or other known forms of hepatitis.

Results
Among the 5539 children tested for SARS-CoV-2, a total of 475 (8.6%) tested positive and 47 (0.8%) presented with hepatitis. Among the 47 children with hepatitis, 37 (79%) had features of CAH-C: having symptoms of hepatitis only, without protracted illness (mean length of stay 5 d), and an uneventful recovery following supportive treatment. In contrast, the remaining 10 (21%) had features of MIS-C–associated hepatitis: multiple system involvement; protracted illness (mean length of stay 8 d); and requiring admission to critical care, with a mortality rate of 30% (3/10).

Conclusions
Our data suggest that CAH-C might be one of the new clinical complications associated with the emergence of newer variants of concern of SARS-CoV-2, which often result in changing presentations. Our findings should facilitate its early identification and thorough workup and aid its differentiation from other emerging syndromes in children, which would help initiate appropriate measures, enable better resource prioritization, and thus limit adversities.
O uso da tecnologia para garantia da dose correta de medicamentos em um hospital do agreste pernambucano
Authors: Silva Bezerra de Sousa Thamiris , Jucelia de França Juciara , Ribeiro de Moura Thaís , Leonardo de Vidal Neves Hugo 
Published: April 2024

Introdução: A farmácia hospitalar tem como responsabilidade contribuir no processo de cuidado à saúde, certificando a utilização correta do fármaco de acordo com sua prescrição, evitando erros associados aos medicamentos. Dessa forma, como medida para minimizar estes erros está o processo de unitarização de doses. Objetivos: Demonstrar uma das estratégias adotadas em um hospital privado, destacando o uso da tecnologia como fator colaborador aliado à diminuição de desperdícios e evasão de medicamentos líquidos, verificar os benefícios após implantação do equipamento no serviço, garantindo eficiência econômica e assistencial. Métodos: Utilizou-se para coleta de dados o relatório de consumo dos medicamentos líquidos orais, emitido através do Sistema Soul MV entre os meses de dezembro de 2022 e janeiro de 2023, do Hospital Unimed Caruaru-Pernambuco. Para o estudo foram selecionadas amostras piloto de quatro medicamentos para análise e comparação de medicamentos prescritos x atendidos. O processamento dos dados foi feito por meio de gráficos. Resultados: Com o uso da máquina unitarizadora de líquidos MK5 ocorreu uma redução significativa de 5,57% no consumo total de frascos, menor divergência no estoque e maior rastreabilidade do produto. Conclusão: Conclui-se que, com a implantação do serviço, houve melhoras no aspecto assistencial e na segurança do paciente, uma vez que contribuiu para a precisão das doses dispensadas e administradas, com isso o contingenciamento de gastos se deu de forma mais equilibrada.
Alocação de recursos públicos para saúde em Macaé entre 2014 e 2017: Reflexões e Desafios
Authors: Silos Alves Natalia , De Souza Serio dos Santos Danielle Maria , Fernandes de Souza Jéssica , Reis Silva Rebeca , Piassi Dias Godói Isabella 
Published: April 2024

Objetivos: Demonstrar a alocação de recursos repassados pelo Fundo Nacional de Saúde para cada Bloco de Financiamento da Saúde do município de Macaé entre 2014 e 2017. Métodos: Estudo quantitativo descritivo, a partir da extração e tabulação de dados disponíveis do Sistema de Informação sobre Orçamentos Públicos em Saúde (SIOPS), bem como de publicações como o Plano Plurianual (2014-2017) do município. Resultados: A partir dos dados extraídos do SIOPS, referente aos repasses do FNS, verificou-se um total de R$174.860.780,76 destinados para saúde de Macaé, sendo destes R$5.457.773,14 (3,12%) direcionados à Assistência Farmacêutica e R$ 40.467.477,50 (23,14%) para a Atenção Básica no período entre 2014 e 2017. Os dados analisados demonstram que Macaé executou, em especial, nos anos de 2015 e 2016, recursos abaixo do previsto pelo Plano Plurianual 2014-2017, o que pode estar associado com a crise do petróleo vivenciada pelo município. Ressalta-se que a redução da arrecadação de impostos pode impactar diretamente na viabilidade da oferta de serviços em saúde, sendo considerado como crítico e delicado para gestores e comunidade, uma vez que muitos indivíduos são dependentes do SUS. Conclusão: Reforça-se a relevância da compreensão das reais demandas e o planejamento racional das necessidades em saúde pelos gestores locais, para que mesmo em momentos de crise orçamentária estes possam se organizar para melhor promover e ofertar os serviços considerados essenciais à sua população.