bluuebunny/crossref_metadata_2025_split huggingface dataset:
De NovoTANGLED1 Recruitment to Aberrant Cell Plate Fusion Sites in Maize
Authors: Uyehara Aimee N. , Diep Beatrice N. , Allsman Lindy A. , Gayer Sarah G. , Martinez Stephanie E. , Kim Janice J. , Agarwal Shreya , Rasmussen Carolyn G. 
Published: March 2024

AbstractDivision plane positioning is critical for proper growth and development in many organisms. In plants, the division plane is established before mitosis, by accumulation of a cytoskeletal structure called the preprophase band (PPB). The PPB is thought to be essential for recruitment of division site localized proteins, which remain at the division site after the PPB disassembles. Here, we show that a division site localized protein, TANGLED1 (TAN1), is recruited independently of the PPB to the cell cortex at sites, by the plant cytokinetic machinery, the phragmoplast. TAN1 recruitment to de novo sites on the cortex is partially dependent on intact actin filaments and the myosin XI motor protein OPAQUE1 (O1). These data imply a yet unknown role for TAN1 and possibly other division site localized proteins during the last stages of cell division when the phragmoplast touches the cell cortex to complete cytokinesis.Summary StatementThe plant division site protein TANGLED1 is recruited tode novocell plate insertion sites independently of the preprophase band.
Combinatorialin vivogenome editing identifies widespread epistasis during lung tumorigenesis
Authors: Hebert Jess D. , Tang Yuning J. , Andrejka Laura , Lopez Steven S. , Petrov Dmitri A. , Boross Gábor , Winslow Monte M. 
Published: March 2024

ABSTRACTLung adenocarcinoma, the most common subtype of lung cancer, is genomically complex, with tumors containing tens to hundreds of non-synonymous mutations. However, little is understood about how genes interact with each other to enable tumorigenesisin vivo, largely due to a lack of methods for investigating genetic interactions in a high-throughput and multiplexed manner. Here, we employed a novel platform to generate tumors with all pairwise inactivation of ten tumor suppressor genes within an autochthonous mouse model of oncogenic KRAS-driven lung cancer. By quantifying the fitness of tumors with every single and double mutant genotype, we show that most tumor suppressor genetic interactions exhibited negative epistasis, with diminishing returns on tumor fitness. In contrast,Apcinactivation showed positive epistasis with the inactivation of several other genes, including dramatically synergistic effects on tumor fitness in combination withLkb1orNf1inactivation. This approach has the potential to expand the scope of genetic interactions that may be functionally characterizedin vivo, which could lead to a better understanding of how complex tumor genotypes impact each step of carcinogenesis.
E-commerce for a sustainable future: integrating trust, green supply chain management and online shopping satisfaction
Authors: Jalil Fazila , Yang Jianhua , Al-Okaily Manaf , Rehman Shafique Ur 
Published: March 2024

PurposeThis study embarks on a comprehensive investigation into the intricate relationship between consumer trust in e-commerce platforms and the adoption of Green Supply Chain Management (GSCM). It delves into a multifaceted analysis of how these dynamics influence the landscape of online shopping, with a specific focus on four critical dimensions: the efficiency of online purchasing processes, the fulfillment of product delivery commitments, the convenience associated with e-platform utilization, and the safeguarding of consumers' personal information.Design/methodology/approachThis research employs sophisticated Structural Equation Modeling (SEM) techniques, facilitated by SPSS and SmartPLS software, to meticulously analyze the amassed data and subject the formulated hypotheses to rigorous testing. The empirical foundation of this study draws from a sample of 377 randomly selected online shoppers, providing a robust basis for its insights.FindingsAt its core, this research is squarely focused on unraveling the dynamics of consumer trust within e-commerce platforms and highlighting the pivotal role played by GSCM in making online shopping more ecologically responsible and sustainable. Of paramount importance is the novel dimension introduced by this study the integration of trust in e-commerce platforms, GSCM practices, and the multifarious dimensions of online shopping all within a unified conceptual framework. Trust on e-commerce platforms leads to GSCM. GSCM determines online shopping satisfaction, i.e. efficiency, fulfillment, convenience, and privacy. Finally, GSCM mediates between trust on e-commerce platforms and online shopping satisfaction.Practical implicationsThis holistic approach represents a ground-breaking contribution to the existing body of literature. It presents a fresh perspective on the intricate interactions that define the contemporary e-commerce landscape.Originality/valueThis initial research integrates trust in e-commerce platforms, GSCM, and online shopping in a single framework through UTAUT2.
Benchmarking for organisational competitiveness: a resource-based view perspective
Authors: Malhotra Gunjan , Dandotiya Gunjan , Shaiwalini Shipra , Khan Adnan , Homechaudhuri Shreya 
Published: March 2024

PurposeThe paper tries to investigate the impact of applications of the resource-based view (RBV) theory in the management field to improve the firm’s profitability. Global firms are innovating and adopting new technology, paving the way to improve their performance.Design/methodology/approachWe have adopted RBV in management practices such as marketing, strategy, finance, and human resources.FindingsRBV has gained researchers' attention with the growing competitive world and new challenges to retaining customers and achieving their pre-defined targets. We attempt to identify the issues related to the usage of RBV in management.Originality/valueUsing RBV in management may help researchers create a competitive mindset and be prepared for uncertain challenges in the business world.
Full harmonic spectrum calculation of magnetic pressures in synchronous permanent magnet machines based on a new realistic partial analytical model: application to SVPWM and DPWM2
Authors: Benharref Salma , Lanfranchi Vincent , Depernet Daniel , Hamiti Tahar , Bazhar Sara 
Published: March 2024

Purpose
The purpose of this paper is to propose a new method that allows to compare the magnetic pressures of different pulse width modulation (PWM) strategies in a fast and efficient way.

Design/methodology/approach
The voltage harmonics are determined using the double Fourier integral. As for current harmonics and waveforms, a new generic model based on the Park transformation and a dq model of the machine was established taking saturation into consideration. The obtained analytical waveforms are then injected into a finite element software to compute magnetic pressures using nodal forces.

Findings
The overall proposed method allows to accelerate the calculations and the comparison of different PWM strategies and operating points as an analytical model is used to generate current waveforms.

Originality/value
While the analytical expressions of voltage harmonics are already provided in the literature for the space vector pulse width modulation, they had to be calculated for the discontinuous pulse width modulation. In this paper, the obtained expressions are provided. For current harmonics, different models based on a linear and a nonlinear model of the machine are presented in the referenced papers; however, these models are not generic and are limited to the second range of harmonics (two times the switching frequency). A new generic model is then established and used in this paper after being validated experimentally. And finally, the direct injection of analytical current waveforms in a finite element software to perform any magnetic computation is very efficient.
Heat transfer analysis of magnetohydrodynamics peristaltic fluid with inhomogeneous solid particles and variable thermal conductivity through curved passageway
Authors: Kanwal Atifa , Khan Ambreen A. , Sait Sadiq M. , Ellahi R. 
Published: March 2024

Purpose
The particle distribution in a fluid is mostly not homogeneous. The inhomogeneous dispersion of solid particles affects the velocity profile as well as the heat transfer of fluid. This study aims to highlight the effects of varying density of particles in a fluid. The fluid flows through a wavy curved passage under an applied magnetic field. Heat transfer is discussed with variable thermal conductivity.

Design/methodology/approach
The mathematical model of the problem consists of coupled differential equations, simplified using stream functions. The results of the time flow rate for fluid and solid granules have been derived numerically.

Findings
The fluid and dust particle velocity profiles are being presented graphically to analyze the effects of density of solid particles, magnetohydrodynamics, curvature and slip parameters. Heat transfer analysis is also performed for magnetic parameter, density of dust particles, variable thermal conductivity, slip parameter and curvature. As the number of particles in the fluid increases, heat conduction becomes slow through the fluid. Increase in temperature distribution is noticed as variable thermal conductivity parameter grows. The discussion of variable thermal conductivity is of great concern as many biological treatments and optimization of thermal energy storage system’s performance require precise measurement of a heat transfer fluid’s thermal conductivity.

Originality/value
This study of heat transfer with inhomogeneous distribution of the particles in a fluid has not yet been reported.
A decade analysis of employees’ well-being and performance while working from home: a bibliometric approach
Authors: Goel Ridhima , Singla Jagdeep , Mittal Amit , Arora Meenal 
Published: March 2024

Purpose
Work-from-home (WFH) has gained popularity over the past years. This study aims to conduct a bibliometric analysis to systematically review and synthesize scholarly literature on the complex interplay between WFH, employee well-being and performance.

Design/methodology/approach
The study incorporates analysis of the bibliometric including performance analysis, content analysis and scientific mapping that is applied to 497 Scopus papers. VOSviewer software was used to evaluate the data.

Findings
This study posits an imbalance between the count of documents and the citations earned by each author. International Journal of Environmental Research and Public Health was regarded as a leading journal with maximum citations and publications. The highest count of publications came from most Asian countries such as India, China, Indonesia and Japan. The investigation indicated that the writers with the maximum citations were predominantly the authors of the majorly cited papers. Further, the text mining through co-occurrence of keyword analysis generated five clusters and cocited references revealed three themes.

Practical implications
The current research might benefit both research groups as well as human resource professionals since it also reveals the research necessity and gaps in the WFH domain.

Originality/value
This research delves into unexplored facets of WFH beyond traditional studies over the past decade by examining remote work arrangements in today’s economy, revealing previously unnoticed dynamics affecting employee well-being and performance. This innovative viewpoint enhances the literature and provides an empirical foundation for strategic organizational decision-making and future study.
The influence of financial flexibility on firm performance: the moderating effects of investment efficiency and investment scale
Authors: Wu Wei , Le Chau , Shi Yulu , Alkaraan Fadi 
Published: March 2024

PurposeFinancial flexibility and investment efficiency are of vital importance in strategic choices at boardrooms, particularly in post-crisis recovery strategies. This study examines the moderating effects of investment efficiency and investment scale on the relationship between financial flexibility and firm performance.Design/methodology/approachThe authors use sample of 10,755 US-listed firms over the period 2010–2021 to examine the relationships between investment scale, investment efficiency, financial flexibility and firm performance. Particular attention is paid to overinvestment and underinvestment.FindingsFindings of this study reveal that financial flexibility mitigates investment inefficiency through reducing overinvestment. Financial flexibility contributes to boost a firm’s accounting and market performance. Additionally, investment efficiency and investment scale have moderating effects on the relationship between financial flexibility and firm performance. However, the influence of investment efficiency is greater than the influence of investment scale. Finally, the authors find that the direct and indirect effects of financial flexibility are stronger on market performance than accounting performance, implying that market is more sensitive to corporate financial policies.Research limitations/implicationsFindings of this study have implications for scholars, decision-makers policymakers, investors and other stakeholders.Practical implicationsThis study has its own limitations due to the sample selection issues, country context and the research model adopted by this study.Originality/valueThe novel contribution to the extant literature is incorporating the influence of investment scale and investment efficiency into the relationship between financial flexibility and firm performance.
Viewpoint: the evolving landscape of peer review
Authors: Mogaji Emmanuel 
Published: March 2024

PurposeThe purpose of this viewpoint is to spotlight the role of reviewers within the collaborative triad of academic publishing. It argues that the significance of reviewers is often disregarded, leading to a gap in our understanding of the peer review process. This perspective emphasizes reviewers as unsung heroes in the publishing ecosystem, providing intentional and thought-provoking insights into the less-discussed yet impactful developments in the evolving peer review landscape.Design/methodology/approachLeveraging the author’s distinguished background as a recipient of theJournal of Service MarketingOutstanding Reviewer Award, this paper offers a personal reflection and synthesised viewpoints on the peer review process. Serving as a representative voice for reviewers, it provides insightful perspectives from the vantage point of a peer reviewer, diverging from conventional editorials and commentaries authored by editors.FindingsAcknowledging the shrinking reviewer pool, this viewpoint suggests a mandatory “review for review” system alongside incentives like editorial positions, while considering financial rewards for reviewers. The rise of generative artificial intelligence (AI) in review prompts ethical concerns but offers solutions for handling diverse submissions and dealing with “Reviewer 2.” While embracing open review for its transparency, potential pitfalls surrounding article confidence and copyright require attention. Ultimately, this viewpoint advocates for a collaborative approach, valuing reviewers, exploring innovative solutions, navigating ethical dilemmas in the technological age and implementing transparent practices responsibly for the betterment of scholarly discourse.Originality/valueThis viewpoint highlights the invaluable contributions of reviewers, enriching the scholarly community and promoting intellectual growth.
Unravelling the biogeographic determinants of tree growth sensitivity to freeze and drought in Canada's forests
Authors: Girardin Martin P. , Guo Xiao Jing , Marchand William , Depardieu Claire 
Published: March 2024

Abstract

The evolutionary dynamics of tree species are influenced by their specific climatic environments, and their ability to persist is determined by adaptive strategies such as broad climate tolerance, phenotypic plasticity or genetic differentiation. Biogeographical predictions indicate that populations located at the edges of their ranges are more likely to experience heightened vulnerability to climatic fluctuations due to approaching tolerance limits. However, if local phenotypic acclimation or genetic adaptation has taken place, trees near the edge of their range could demonstrate comparable sensitivity to freeze and drought as the rest of the sampled population. Nevertheless, there remains uncertainty regarding the extent of developmental and evolutionary adjustments in climate sensitivity across the entire ranges of many tree species.

Here, we document the biogeography of tree growth sensitivity to freeze and soil water and vapour pressure deficits during 1950–2018 using an extensive multi‐species tree‐ring dataset of 35,784 trees at 4535 sites covering boreal, temperate conifer and temperate deciduous forests of Canada. We quantify the relationships between tree radial growth increment and seasonal climate variables and explore factors driving the observed patterns of annual growth and climate sensitivity such as species, regional climate and local site conditions, and tree age and size.

Freeze and drought had widespread impacts on tree growth that were contingent on the presence of focal species in interaction with tree size. An indirect growth thermal limitation towards cold/wet edges, occurring through the site moisture conditions, was observed in seven widespread species (e.g. Picea glauca, Picea mariana and Larix laricina). Moreover, six species had negative drought impacts more strongly expressed towards their warm/dry edges (e.g. Abies balsamea, Betula papyrifera and Pseudotsuga menziesii). However, widespread Picea, Pinus and Populus species showed no indication of increased sensitivity to soil water conditions at these edges.

Synthesis. Our findings support the idea of evolutionary or acclimatization adjustments in the development of populations in response to long‐term climate conditions experienced in their respective locations. This underscores the importance of incorporating phenotypic and genomic data into future analyses of climate change impacts, which would enhance our ability to predict potential ecological shifts.
Rural–urban differences in out‐of‐network treatment initiation and engagement rates for substance use disorders
Authors: Raver Eli , Retchin Sheldon M. , Li Yiting , Carlo Andrew D. , Xu Wendy Y. 
Published: March 2024

AbstractObjectiveTo examine rural–urban disparities in substance use disorder treatment access and continuation.Data Sources and Study SettingWe analyzed a 2016–2018 U.S. national secondary dataset of commercial insurance claims.Study DesignThis cross‐sectional study examined individuals with a new episode of opioid, alcohol, or other drug use disorders. Treatment initiation and engagement rates, and rates of using out‐of‐network providers for these services, were compared between rural and urban patients.Data CollectionWe included individuals 18–64 years old with continuous employer‐sponsored insurance.Principal FindingsPatients in rural settings experienced lower treatment initiation rates for alcohol (36.6% vs. 38.0%, p < 0.001), opioid (41.2% vs. 44.2%, p < 0.001), and other drug (37.7% vs. 40.1%, p < 0.001) use disorders, relative to those in urban areas. Similarly, rural patients had lower treatment engagement rates for alcohol (15.1% vs. 17.3%, p < 0.001), opioid (21.0% vs. 22.6%, p < 0.001), and other drug (15.5% vs. 17.5%, p < 0.001) use disorders. Rural patients had higher out‐of‐network rates for treatment initiation for other drug use disorders (20.4% vs. 17.2%, p < 0.001), and for treatment engagement for alcohol (27.6% vs. 25.2%, p = 0.006) and other drug (36.1% vs. 31.1%, p < 0.001) use disorders.ConclusionsThese findings indicate that individuals with substance use disorders in rural areas have lower rates of initial and ongoing treatment, and are more likely to seek care out‐of‐network.
Landscape‐level determinants of the performance of an agglomeration bonus in conservation auctions
Authors: Nguyen Chi , Latacz‐Lohmann Uwe , Hanley Nick 
Published: March 2024

AbstractThe agglomeration bonus (AB) has been advocated as an incentive mechanism to boost spatially coordinated conservation efforts, where such coordination is thought to be beneficial to achieving biodiversity or other ecological outcomes. Specifically, an AB is paid to individual landholders if their conserved habitats are spatially connected to the conserved habitats of adjacent neighbours. This paper employs a series of controlled lab experiments with agriculture students to investigate the performance of AB in budget‐constrained discriminatory‐price auctions across different landscape types. We focus on the spatial correlation of opportunity costs and environmental benefits as one potentially important aspect of the landscape. We set up a stylised agricultural landscape where the conservation agency aims to connect fragmented wildlife habitats by incentivising farmers to enrol land in a conservation programme. We investigate the effects of an AB in landscapes where opportunity costs and environmental benefits are uncorrelated, negatively correlated or positively correlated over space. We found that the benefits of an AB in improving landscape‐scale environmental outcomes were significant in the positive correlation landscape. However, the AB resulted in worse outcomes in the uncorrelated and negative landscapes.
A molecular index for biological age identified from the metabolome and senescence‐associated secretome in humans
Authors: Hamsanathan Shruthi , Anthonymuthu Tamil , Prosser Denise , Lokshin Anna , Greenspan Susan L. , Resnick Neil M. , Perera Subashan , Okawa Satoshi , Narasimhan Giri , Gurkar Aditi U. 
Published: March 2024

AbstractUnlike chronological age, biological age is a strong indicator of health of an individual. However, the molecular fingerprint associated with biological age is ill‐defined. To define a high‐resolution signature of biological age, we analyzed metabolome, circulating senescence‐associated secretome (SASP)/inflammation markers and the interaction between them, from a cohort of healthy and rapid agers. The balance between two fatty acid oxidation mechanisms, β‐oxidation and ω‐oxidation, associated with the extent of functional aging. Furthermore, a panel of 25 metabolites, Healthy Aging Metabolic (HAM) index, predicted healthy agers regardless of gender and race. HAM index was also validated in an independent cohort. Causal inference with machine learning implied three metabolites, β‐cryptoxanthin, prolylhydroxyproline, and eicosenoylcarnitine as putative drivers of biological aging. Multiple SASP markers were also elevated in rapid agers. Together, our findings reveal that a network of metabolic pathways underlie biological aging, and the HAM index could serve as a predictor of phenotypic aging in humans.