bluuebunny/crossref_metadata_2025_split huggingface dataset:
On nonnil-S-Noetherian and nonnil-u-S-Noetherian rings
Authors: Mahdou Najib , Oubouhou El Houssaine , Celikel Ece Yetkin 
Published: February 2025

Abstract
Let R be a commutative ring with identity, and let S be a multiplicative subset of R. Then R is called a nonnil-S-Noetherian ring if every nonnil ideal of R is S-finite. Also, R is called a u-S-Noetherian ring if there exists an element s ∈ S such that for each ideal I of R, sI ⊆ K for some finitely generated sub-ideal K of I. In this paper, we examine some new characterization of nonnil-S-Noetherian rings. Then, as a generalization of nonnil-S-Noetherian rings and u-S-Noetherian rings, we introduce and investigate the nonnilu-S-Noetherian rings class.
Learning to Shape Transformation – How Individual Schools can be Supported in Implementing a Newly Developed ESD Curriculum with Training Concept
Authors: Lindau-Bank Detlev , Stein Margit 
Published: February 2025

Abstract
When implementing projects in the field of education for sustainable development (ESD), there is always a great need for further training and qualification for the teaching staff if ESD needs to be implemented systematically and school-wide in the lessons of all year groups and subjects. Successful implementation of ESD in the school context depends on two influencing factors. On the one hand, schools need a practicable framework curriculum for ESD and, on the other hand, a related further education concept that can be implemented primarily in school practice.
The main aim of the article is to outline the framework curriculum and the training concept and to present the initial results of an evaluation of the training carried out on this basis in a Latvian, Romanian and German schools.
This article reports on an ERASMUS + project that has dedicated itself to this task from a European perspective. Building on the framework curriculum, a customized training concept was developed to impart content and skills for teachers and educational staff. Both the framework curriculum and the training concept as well as the handout can be downloaded free of charge in six languages: https://esdsupervision.eu/.
The most important finding of the project is that the curriculum framework and the training program tailored to it are seen as effective and efficient, but also that accompanying advice is necessary for a school development process.
Effect of Hyperbaric Oxygenation on the Severity of Experimental Autoimmune Myocarditis in Gal-3 Deficient Mice
Authors: Milincic Katarina , Kovacevic Marina Miletic , Dulovic Dragan , Ljujic Biljana 
Published: February 2025

Abstract
Myocarditis is an inflammatory heart disease, which is characterized by the presence of a cellular infiltrate in the myocardial interstitium, along with the degeneration and necrosis of cardiomyocytes. Depending on the predominate immune mechanism in the disease, Gal-3 may either attenuate or enhance the development of inflammation. Treatment with hyperbaric oxygenation (HBO) is considered a promising adjunctive therapy for cardiovascular disease due to increasing evidence of its beneficial effect on myocardial function. The potential effects of HBO treatment on myocarditis in animal models have not been investigated. The aim of this study was to delineate the impact of HBO on both the clinical course and histochemical characteristics of EAM. EAM was induced in Gal-3-deficient mice on the C57BL/6J background by immunization with myosin peptide MyHCα334–352. The EAM group treated with HBO characteristically showed a significant improvement in FS compared to the untreated EAM group, as well as a reduction in LVIDd and LVIDs. Gal-3KO mice developed more severe myocarditis, characterized by accumulation of mononuclear cells and single mononuclear cells between cardiomyocytes, than animals treated with HBO. Additionally, EAM mice receiving HBO treatment showed a lower degree of degeneration and necrosis compared to the untreated EAM group. A significant reduction in fibrosis was noted in Gal-3KO mice with EAM after HBO treatment compared to the untreated group of EAM mice. The results showed that HBO treatment can improve cardiac function, reduce cardiac inflammatory infiltration, myocardial necrosis, and fibrosis, which could alleviate cardiac remodeling, dilated cardiomyopathy, and subsequent development of heart failure.
Remote sensing forest health assessment – a comprehensive literature review on a European level
Authors: Drechsel Johannes , Forkel Matthias 
Published: February 2025

Abstract
Forest health assessments (FHA) have been carried out at European level since the 1980s in order to identify forest damage. The annual surveys are usually conducted without the use of remote sensing tools. However, the increasing availability of remote sensing observations potentially allows conduct FHA more wide-spread, more often, or in more comprehensive and comparable way. This literature review systematically evaluated 110 studies from 2015 to 2022 that use remote sensing for FHA in Europe. The purpose was to determine (1) which tree species were studied; (2) what types of damage were evaluated; (3) whether damage levels are distinguished according to the standard of the International Co-operative Program on Assessment and Monitoring of Air Pollution Effects on Forests (ICP-Forest); (4) the level of automation; and (5) whether the findings are applicable for a systematic FHA. The results show that spruce is the most studied tree species. Damage caused by bark beetles and drought were predominantly studied. In most studies only 2 damage levels are classified. Only four studies were able to perform a comprehensive FHA by identifying individual trees, classifying their species and damage levels. None of the studies investigated the suitability of their remote sensing approach for systematic forest health assessments. This result is surprising since programs such as SEMEFOR analyzed the potential of remote sensing for FHA already in the 1990s. We conclude that the availability of new satellite systems and advances in artificial intelligence and machine learning should be translated into FHA practice according to ICP standards.
Assessing crown reduction as a strategy to mitigate drought stress during initial development of sessile oak and Norway spruce saplings
Authors: Arsić Janko , Stojanović Marko , Horáček Petr , Mikhailov Sergei , Krejza Jan 
Published: February 2025

Abstract
Droughts, amplified by climate change, pose a significant threat to the success of both artificially and naturally regenerated forests. Understanding how these changes affect the initial stages of saplings development is crucial for forest establishment, particularly for ecologically and economically important species like Norway spruce and sessile oak in Central Europe. This study investigated the impact of crown reduction (CR) by 50% of crown length on saplings of each species. Automatic dendrometers were installed on 24 saplings per species to precisely monitor growth and water-related stem changes. The main objective was to investigate the potential ameliorative effect of CR on water-stressed saplings during their initial development. Our study hypothesized that CR, by decreasing leaf area and consequently water use, would improve water availability and facilitate sapling growth. The results indicate that CR may enhance soil water availability thereby supporting the growth of water-stressed Norway spruce saplings but not those of sessile oak. The tree water deficit – an indicator of tree water status – significantly improves in Norway spruce saplings subjected to CR (p < 0.05). Conversely, this treatment resulted in the depletion of stem water status in sessile oak saplings. The species-specific growth phenology revealed that CR led to an increase in the number of growing days for Norway spruce compared to sessile oak saplings. In summary, CR may be considered a beneficial method for alleviating stress in Norway spruce saplings, especially during drought. In addition, further testing in field conditions is necessary to confirm these results.
Correlation between fecal biomarkers and the presence of antineutrophil cytoplasmic antibodies with ulcerative colitis disease activity
Authors: Büşra Usta , Demet Gür Vural , Asuman Birinci , Müge Ustaoğlu Dede 
Published: February 2025

Abstract

Background
Although colonoscopy remains the gold standard for Ulcerative colitis (UC) diagnosis due to its invasive and costly nature, non-invasive biomarkers are gaining importance in disease activity monitoring and diagnosis. In our study, we aimed to evaluate the correlation of fecal calprotectin (FC) and fecal lactoferrin (FL) levels with the disease activity according to 3 different disease activity indices and to investigate the relationship between the presence of peri-nuclear anti-neutrophil antibody (p-ANCA) and disease activity.

Methods
Our study was planned as a prospective cohort study and 80 patients diagnosed with UC who were admitted to the Gastroenterology department between 01.05.2023 and 01.09.2023 at Ondokuz Mayıs University Hospital were included in the study. ‘Truelove and Witts’ (TLW) activity index, SEO index and Mayo Score were applied. FC and FL levels in stool samples were analysed by Enzyme-Linked ImmunoSorbent Assay (ELISA), while p-ANCA presence in blood samples was examined using the Indirect Immunofluorescent Antibody (IIFA) method.

Results
It has been demonstrated that both faecal biomarkers can distinguish severe disease, but according to ROC analysis, the discriminatory power of FC is higher than that of FL. The cutt-off values calculated for severe disease were found above 300µg/g for FC and above 130µg/g for FL. Also ANCA positivity and formalin-resistant ANCA positivity in the severe disease group were statistically higher than mild disease group.

Conclusions
In addition to the relationship between faecal biomarkers and disease activity, our results demonstrated that patients with severe disease exhibited high rates of ANCA positivity and formalin resistance.
A diagnostic classifier for osteoarthritis constructed based on cuprotosis-related genes
Authors: Xiaopeng Jia , Honglu Chen , An Li 
Published: February 2025

Abstract

Background
Osteoarthritis (OA), a common degenerative joint disease, is pathologically characterized by joint pain and functional limitation. Cuprotosis-related genes (CRGs) exert vital biological effects on various diseases, but their functions in OA remain largely unknown. We aimed to explore the potential role of CRGs in OA and to establish a diagnostic classifier.

Methods
The Gene Expression Omnibus database was firstly employed to collect data sets on several controls and OA samples. Batch correction was conducted using RobustRankAggreg and sva package to remove the systematic errors between different batches of sequencing. The limma package was utilized to screen differentially expressed genes, and CRGs were identified through Pearson correlation analysis.

Results
A total of 2,033 CRGs were identified after analyzing several data sets. Through Least Absolute Shrinkage and Selection Operator COX model and support vector machine-recursive feature elimination classifier, 6 crucial CRGs were finally determined, including biglycan, Ephrin-A3, leukemia inhibitory factor, natural killer cell granule protein 7, stimulator of chondrogenesis 1 and tumor necrosis factor, alpha-induced protein 3. The integrated analysis on these genes revealed that they had high prediction performance. The area under the curve was 0.772 in the training set and 0.693 in the validation set. These crucial CRGs exhibited significant correlations with the infiltration of M2 macrophages, resting mast cells and other immune cells.

Conclusions
A diagnostic classifier for OA was successfully constructed based on CRGs, and significant associations are found between crucial CRGs and immune microenvironment in OA.
A comparative study of legislative and normative frameworks in Morocco, France and U.S.A towards progressive and evolutionary quality management in Moroccan laboratories
Authors: Kharrazi Anass , El Ftouh Sobha , El Feniche Mohammed , Bahji Mostafa , Bouaiti El Arbi 
Published: February 2025

Abstract

Introduction
Establishing and maintaining quality standards in medical laboratories is a significant challenge due to the rapid advancements in analysis techniques and technologies. In Morocco, the “Guide de Bonne Execution des Analyses’’ (GBEA) is the primary regulation framework overseeing quality assurance in laboratories. However, it does not adequately address potential gaps that could compromise patient safety.

Methods
In this article, we compared five quality management systems through normative frameworks in Morocco, France, and the United States to develop an enhanced model adapted to the Moroccan context.

Results
The comparison reveals that the extensive roles and responsibilities of a laboratory director and the inability to delegate tasks to qualified staff members in the Moroccan GBEA pose a challenge to the effective leadership and detection of non-conformities. Adopting the French GBEA, the Clinical Laboratory Improvement Amendments CLIA and the International Standardization Organization ISO 15189 Documentation model that covers all analytical phases, process and procedure reviews, and robust quality control measures could serve as strengths in achieving successful accreditation without compromising the laboratory's technical, administrative, and financial stability. The principles of risk management and safety are increasingly important in the analytical process to ensure ongoing improvement and the safety of both staff and patients.

Conclusions
In this sense, adopting a progressive model, starting with detailed documentation, quality control, staff qualification and adaptation of requirements to the Moroccan context will enable medical laboratories to achieve quality without putting them in administrative and financial challenges while preserving continuous improvement.
Governance in Universities: the Mechanism of Leadership and the Experience of the Federal University of Sergipe
Authors: Alves Fred Amado Martins , Sales Jefferson David Araújo , Santos Sindiany Suelen Caduda dos , Souza Roberto Rodrigues de 
Published: February 2025

Objective: To analyze the need to consolidate governance systems in Federal Universities, highlighting leadership as an essential pillar and using the Federal University of Sergipe (UFS) as a reference.

Theoretical Framework: The research is grounded in the concepts of public governance as described in Decree No. 9,203/2017 and the guidelines of the Federal Court of Accounts (TCU). Leadership is emphasized as a central element. Within the context of federal universities, the study examines the impact of governance on the interaction with institutional autonomy, while addressing challenges and innovations in the field, such as the experience of the Federal University of Sergipe (UFS).

Method: A document analysis of key governance and management documents from Brazilian federal universities was conducted, with a focus on the Federal University of Sergipe. The UFS document analysis covered a time frame of eight years. The results were organized into categories.

Results and Discussion: The research identified significant advances in the governance of the Federal University of Sergipe (UFS). The findings show improvements in performance indicators, aligned with the guidelines of Decree No. 9,203/2017 and the TCU. Nevertheless, challenges remain. The proposal of a research agenda underscores the need to deepen the discussion and explore new solutions.

Research Implications: The practical and theoretical implications of this research include consolidating governance systems as a reference for strengthening public university management.

Originality/Value: The research contributes to the formulation of guidelines and replicable models for other federal universities, fostering greater institutional cohesion and alignment with public policies.
Agro-Ecotourism as a Model for Rural Development in the Mountains Region: Amedy Region as Case Study
Authors: Hussein Lailan T. , Raswel Layla M. 
Published: February 2025

Objective: This study aims to examine the determinants and indicators of Amedy's region competitiveness to identify the optimal model for rural development via tourism.

Theoretical Framework: Rural tourism has emerged as a controversial topic within rural development. The combination of the decline of agriculture, the rise of tourism, and the need for economic diversification necessitates the creation of a new rural development model that ensures both economic diversification and environmental conservation.

Method: Qualitative data was acquired from a local perspective through semi-structured interviews based on saturation theory. Thematic analysis was performed on interview transcriptions from 81 rural inhabitants to identify key themes

Results and Discussion: The results confirmed that Agro-ecotourism is the best model of rural tourism devlopmnet in mountain region. The growth in local agricultural sales and increased tourist numbers are markers of economic prosperity. The region's agricultural goods and natural resources are key factors influencing rural competitiveness; nevertheless, climate change, conflicts over water and land, and poor governance have negatively affected their management. The interplay between security and accessibility obstructs rural tourism development. The study revealed direct and indirect relationships between the variables, suggesting that inadequacies in one area impact the others.

Research Implications: Rural areas with similar environmental, economic, and cultural challenges can utilize the findings as an integrative model for preserving agricultural identity and natural resources.

Originality/Value: The model is novel and has not been previously observed in Iraq and Kurdistan.
Variations in functional outcome based on hamstring autograft thickness estimated using transportal technique in arthroscopic anterior cruciate ligament reconstruction
Authors: Radhik K. R. , Arumugam A. K. , Kumar V. Manooj , Kumar S. Venkatesh , Koramutla Harsha Kumar 
Published: February 2025

Objectives:
We aimed to study the functional outcome difference in arthroscopic anterior cruciate ligament reconstruction (ACLR) using hamstring autograft thickness between more than 85% and ≤85%.

Materials and Methods:
In our study, 50 patients with anterior cruciate ligament (ACL) tears were operated with arthroscopic ACLR using an autologous hamstring graft. The anteroposterior diameter (APD) of the tibial footprint of ACL is measured using an arthroscopic ruler using a transportal and the graft thickness of more than 70% of the tibial footprint APD was used. The international knee documentation committee and knee society score (KSS) were compared between the groups in the 1st month, 6th month, and 12th month between autograft thickness of >85% and ≤85%.

Results:
The mean IKDC scores of patients with graft thickness >85% were higher compared to graft thickness ≤85% in the 6th and 12th post-operative months, with a statistically significant difference at the 12th post-operative month. The mean KSS scores of patients with graft thickness >85% were higher compared to graft thickness ≤85% at the 3rd, 6th, and 12th post-operative months, with a statistically significant difference at the 12th post-operative month.

Conclusion:
The functional scores were better for autograft thickness of more than 85% compared to autograft thickness of ≤85% at short-term follow-up of the 3rd and 6th post-operative month with a statistical difference at long-term follow-up of the 12th month.
Концептуальна модель емерджентної ефективності на основі «теореми шнурків» як інструмент управління результативністю в органах досудового розслідування
Authors: Гюльмагомедов Денис Олександрович , Гарафонова Ольга Іванівна 
Published: February 2025

Запропоновано новий підхід до оцінки ефективності органів досудового розслідування на основі концепції емерджентності та мережевого аналізу ключових показників ефективності органу досудового розслідування. Система ключових показників ефективності розглядається як складна інтегральна система, де виникнення нових властивостей (ефективності) є результатом взаємодії окремих елементів (показників). За допомогою формули площі Г.Мейстера і К.Ф. Гаусса «теорема шнурків» розраховується інтегральний показник ефективності, що дозволяє оцінити загальну результативність системи. Для візуалізації та аналізу співвідношення результату та витрат розроблена геометрична модель. Ключові показники результативності відображаються як точки (кути) многокутника, а витрати – як вписане в нього коло. Різниця між площею многокутника та кола демонструє додаткову ефективність системи від її номінальної ефективності. Запропонована модель заснована на ідеї створення інструмента для керівників правоохоронних органів та їх стейкхолдерів, який дозволяє візуально сприймати і швидко оцінювати ступінь ефективності діяльності організації, збалансованість показників результативності, які досягнуті на відповідний момент часу. Така модель має концептуальну аналогію з: Пентагон-моделлю; П’ятикутною призмою ефективності; Моделлю RADAR (EFQM). Концептуальна модель надає керівникам правоохоронних органів візуальний інструмент оцінки, де площа многокутника результатів, що виступає за межі кола витрат, демонструє додатково створену цінність та характеризує рівень емерджентної ефективності організації. При цьому наближення кутів многокутника до тупих свідчить про вищу збалансованість відповідних показників результативності, тоді як гострі кути вказують на наявність дисбалансу, що потребує управлінського втручання.
Evaluasi Dampak Proses Retrogression dan Reaging dalam Meningkatkan Ketahanan Korosi pada Material AL7175
Authors: Septianissa Selly 
Published: February 2025

Paduan aluminium 7175 dan seri 7xxx lainnya dikenal memiliki ketahanan korosi sumuran yang rendah. Untuk meningkatkan ketahanan korosi sambil mempertahankan kekuatan, penelitian ini menerapkan metode retrogression dan reaging (RAA), yang merupakan perlakuan panas baru untuk paduan aluminium yang mengalami penguatan presipitasi. Tujuan dari penelitian ini adalah untuk mengevaluasi pengaruh proses RAA terhadap ketahanan korosi sebelum anodisasi asam kromat (CAA) pada dua tegangan, yaitu 20 V dan 40 V. Pengujian yang dilakukan meliputi analisis struktur mikro, komposisi kimia, pengujian kekerasan, ketebalan lapisan, dan ketahanan korosi menggunakan metode salt spray testing. Hasil metalografi menunjukkan pembentukan dua fase, yaitu fase MgZn2 yang terdistribusi di dalam butir. Pengujian salt spray selama 500 jam menunjukkan bahwa material yang melalui proses CAA 20 V dan RAA tidak mengalami korosi sumuran, sementara material dengan CAA 40 V menunjukkan 20 pit akibat anodisasi yang kurang baik. Penelitian ini mengindikasikan bahwa presipitat MgZn2 yang terbentuk melalui proses RAA berkontribusi pada peningkatan ketahanan korosi material paduan aluminium 7175.