bluuebunny/crossref_metadata_2025_split huggingface dataset:
DG-based joint transmission-reflection traveltime tomography and its application of borehole seismic data
Authors: Chen Xin , Zhu Zhaolin , Cao Danping 
Published: April 2024

Abstract
The limitations of the coverage range and density of transmission wave often result in less-than-ideal results in traveltime tomography. By contrast, joint transmission-reflection traveltime tomography can not only recover deep structures that transmission tomography cannot detect, but also optimize its inversion results. In this article, we perform joint tomography on borehole seismic (vertical seismic profile, reverse vertical seismic profile, and crosswell seismic) data to obtain near-wellbore structures. In the first part, we solve the factored eikonal equation by the discontinuous Galerkin (DG) method to calculate the transmission/reflection traveltime. Owing to the large wavefront curvature near the source point, the traveltime errors generated by the numerical simulation will propagate from the source to all the calculation domains. According to the factorization principle, the equation solution is decomposed into two parts to solve the point-source singularity. To further improve the accuracy of solving traveltime, we use the DG method to solve the factored eikonal equation with additive factors (the factored DG method), obtaining second-order accuracy solution. The adjoint-state method is employed in the inversion section to calculate the gradient of the misfit function. We use the traveltime difference observed inside the model to define the misfit function, which is more suitable for borehole seismic and avoids the influence of surface normal vectors on gradients. Numerical tests applied on models indicate that the joint tomography method has the potential to accurately inverse the seismic structure information near the well and recover the deep underground structure.
Remini-Sing RCT: Therapeutic Choir Participation for Community-Dwelling People with Dementia and Their Primary Caregivers
Authors: Tamplin Jeanette , Thompson Zara , Clark Imogen N , Teggelove Kate , Baker Felicity A 
Published: April 2024

Abstract
Dementia negatively affects the wellbeing of both caregivers and care recipients. Community-based therapeutic choir singing offers opportunities for music participation and social engagement that are accessible and mutually enjoyable for people with dementia and their family caregivers and promotes shared and meaningful musical interactions, which may support relationship quality. This study aimed to investigate the impact of the Remini-Sing therapeutic choir intervention on relationship quality, quality of life, depression, and social connectedness for dyads, as well as caregiver burden and care recipient anxiety. A randomized-controlled trial design was used with a target sample of 180 dyads. Due to recruitment difficulties, 34 participant dyads were recruited and randomly assigned to a 20-week group singing condition (n = 16) or a waitlisted control group (n = 18). Participant dyads consisted of people with dementia and their family caregivers who resided at home in the community. The Remini-Sing therapeutic choirs were held in community settings. Assessments were conducted by masked assessors at baseline, 11 weeks, and 21 weeks. Twenty-one dyads completed assessments at the primary timepoint (Week 11). Issues with recruitment and retention resulted in an unpowered study with no statistically significant findings. Mean decreases in anxiety and depression for choir participants with dementia were supported by medium to large effect sizes, indicating a potential intervention effect to be explored in future powered studies. Key learnings related to study design are discussed regarding recruitment, retention, participant burden, and sustainability, with recommendations made for future dementia research.
Prevalence and associated factors of sexual, psychological, and physical violence among physical therapists in their clinical role in Spain: a national web-based cross-sectional survey
Authors: Boo-Mallo Tania , Oviedo-de-la-Fuente Manuel , Martínez-Rodríguez Alicia 
Published: April 2024

Abstract

Objectives:
To determine the extent of career-long and 12-month exposure to sexual, physical, and psychological/verbal violence committed by patients or their companions among physical therapists in Spain. Additionally, to identify the factors associated with such exposure.

Methods:
This study employed an observational cross-sectional approach. Initially, a questionnaire was developed and validated using a convenience sample. Subsequently, it was distributed via email to all physical therapists registered in Spain in the first quarter of 2022. Individual risk models were created for each type of violence experienced within the past 12 months.

Results:
The prevalence of violence encountered by physical therapists throughout their careers was 47.9% for sexual violence, 42.7% for psychological/verbal abuse, and 17.6% for physical abuse. Lower values were observed within the last 12 months (13.4%, 15.8%, and 5.2%, respectively). Statistical risk modeling for each type of violence experienced in the past 12 months indicated that the common precipitating factor for all forms of violence was working with patients with cognitive impairment. Working part-time appeared to be a protective factor. Other factors, such as the practitioners’ gender, practice setting, or clinic location showed variations among the diverse types of violence.

Conclusions:
The exposure to type II workplace violence within the last 12 months among physical therapists in Spain (Europe) is not so high as in some other world regions. Various individual, clinical, and professional/organizational risk factors have been identified in connection with type II workplace violence. Further research is warranted to compare the violence experienced once the COVID pandemic has subsided.
Proton beam reirradiation for locally recurrent rectal cancer patients with prior pelvic irradiation
Authors: Takagawa Yoshiaki , Suzuki Motohisa , Seto Ichiro , Azami Yusuke , Machida Masanori , Takayama Kanako , Sulaiman Nor Shazrina , Nakasato Tatsuhiko , Kikuchi Yasuhiro , Murakami Masao , Honda Michitaka , Teranishi Yasushi , Kono Koji 
Published: April 2024

Abstract
The aim of the present study was to report the feasibility of proton beam reirradiation for patients with locally recurrent rectal cancer (LRRC) with prior pelvic irradiation. The study population included patients who were treated with proton beam therapy (PBT) for LRRC between 2008 and December 2019 in our institution. Those who had a history of distant metastases of LRRC, with or without treatment, before reirradiation, were excluded. Overall survival (OS), progression-free survival (PFS) and local control (LC) were estimated using the Kaplan–Meier method. Ten patients were included in the present study. The median follow-up period was 28.7 months, and the median total dose of prior radiotherapy (RT) was 50 Gy (range, 30 Gy–74.8 Gy). The median time from prior RT to reirradiation was 31.5 months (range, 8.1–96.6 months), and the median reirradiation dose was 72 Gy (relative biological effectiveness) (range, 56–77 Gy). The 1-year/2-year OS, PFS and LC rates were 100%/60.0%, 20.0%/10.0% and 70.0%/58.3%, respectively, with a median survival time of 26.0 months. Seven patients developed a Grade 1 acute radiation dermatitis, and no Grade ≥ 2 acute toxicity was recorded. Grade ≥ 3 late toxicity was recorded in only one patient, who had developed a colostomy due to radiation-related intestinal bleeding. Reirradiation using PBT for LRRC patients who had previously undergone pelvic irradiation was feasible. However, the indications for PBT reirradiation for LRRC patients need to be considered carefully due to the risk of severe late GI toxicity.
Risk of major adverse cardiovascular events in rural vs urban settings among patients with erectile dysfunction: a propensity-weighted retrospective cohort study of 430 621 men
Authors: Mann Uday , Bal Dhiraj S , Panchendrabose Kapilan , Brar Ranveer , Patel Premal 
Published: April 2024

Abstract

Background
The relationship between erectile dysfunction (ED) and cardiovascular (CV) events has been postulated, with ED being characterized as a potential harbinger of CV disease. Location of residence is another important consideration, as the impact of rural residence has been associated with worse health outcomes.

Aim
To investigate whether men from rural settings with ED are associated with a higher risk of major adverse CV events (MACEs).

Methods
A propensity-weighted retrospective cohort study was conducted with provincial health administrative databases. ED was defined as having at least 2 ED prescriptions filled within 1 year. MACE was defined as the first hospitalization for an episode of acute myocardial infarction, heart failure, or stroke that resulted in a hospital visit &gt;24 hours. We classified study groups into ED urban, ED rural, no ED urban, and no ED rural. A multiple logistic regression model was used to determine the propensity score. Stabilized inverse propensity treatment weighting was then applied to the propensity score.

Outcomes
A Cox proportional hazard model was used to examine our primary outcome of time to a MACE.

Results
The median time to a MACE was 2731, 2635, 2441, and 2508 days for ED urban (n = 32 341), ED rural (n = 18 025), no ED rural (n = 146 358), and no ED urban (n = 233 897), respectively. The cohort with ED had a higher proportion of a MACE at 8.94% (n = 4503), as opposed to 4.58% (n = 17 416) for the group without ED. As compared with no ED urban, no ED rural was associated with higher risks of a MACE in stabilized time-varying comodels based on inverse probability treatment weighting (hazard ratio, 1.06-1.08). ED rural was associated with significantly higher risks of a MACE vs no ED rural, with the strength of the effect estimates increasing over time (hazard ratio, 1.10-1.74).

Clinical Implications
Findings highlight the need for physicians treating patients with ED to address CV risk factors for primary and secondary prevention of CV diseases.

Strengths and Limitations
This is the most extensive retrospective study demonstrating that ED is an independent risk factor for MACE. Due to limitations in data, we were unable to assess certain comorbidities, including obesity and smoking.

Conclusions
Our study confirms that ED is an independent risk factor for MACE. Rural men had a higher risk of MACE, with an even higher risk among those who reside rurally and are diagnosed with ED.
Genetic factors acting prior to dormancy in sour cherry influence bloom time the following spring
Authors: Goeckeritz Charity Z , Grabb Chloe , Grumet Rebecca , Iezzoni Amy F , Hollender Courtney A 
Published: April 2024

Abstract
Understanding the process of Prunus species floral development is crucial for developing strategies to manipulate bloom time and prevent crop loss due to climate change. Here, we present a detailed examination of flower development from initiation until bloom for early- and late-blooming sour cherries (Prunus cerasus) from a population segregating for a major bloom time QTL on chromosome 4. Using a new staging system, we show floral buds from early-blooming trees were persistently more advanced than those from late-blooming siblings. A genomic DNA coverage analysis revealed the late-blooming haplotype of this QTL, k, is located on a subgenome originating from the late-blooming P. fruticosa progenitor. Transcriptome analyses identified many genes within this QTL as differentially expressed between early- and late-blooming trees during the vegetative-to-floral transition. From these, we identified candidate genes for the late bloom phenotype, including multiple transcription factors homologous to Reproductive Meristem B3 domain-containing proteins. Additionally, we determined that the basis of k in sour cherry is likely separate from candidate genes found in sweet cherry—suggesting several major regulators of bloom time are located on Prunus chromosome 4.
A Chandra search for periodic X-ray sources in the bulge of M31
Authors: Zhang Jiachang , Bao Tong , Li Zhiyuan 
Published: April 2024

ABSTRACT
We present a systematic search for periodic X-ray sources in the bulge of M31, using ∼2 Ms of archival Chandra observations spanning a temporal baseline of 16 yr. Utilizing the Gregory–Loredo algorithm that is designed for photon-counting, phase-folded light curves, we detect seven periodic X-ray sources, among which four are newly discovered. Three of these sources are novae, the identified periods of which range between 1.3 and 2.0 h and are most likely the orbital period. The other four sources are low-mass X-ray binaries, the identified periods of which range between 0.13 and 19.3 h and are also likely orbital due to a clear eclipsing/dipping behaviour in the light curve. We address implications on the X-ray binaries population of the M31 bulge. Our study demonstrates the potential of using archival X-ray observations to systematically identify periodic X-ray sources in external galaxies, which would provide valuable information about the underlying exotic stellar populations.
Fatima’s inheritance: Law, Islam, and gendered archive-making in India’s early modern global connections
Authors: Fei Du 
Published: April 2024

Abstract
Sometime around the first half of the seventeenth century, a Muslim woman known by the name Fatima brought her slaves to court over an inheritance dispute in the Indian port city of Surat. Tracing Fatima’s lawsuit and its many afterlives through the study of the transmission of its sole surviving record, this article charts the genealogies of the gendered (re)interpretations of the meaning of law and Islam from the courtroom of Surat to a Mughal official’s anthology and to a French Orientalist’s library. Along the way, Fatima’s invocation of divine legal authority in protecting her right of inheritance became abstracted by the Mughal official into a Persianate scribal articulation of ideal social order that saw the masculine as the default gender of law. This scribal vision of order then converged with the Orientalist’s universalist narrative of natural law that struggled to comprehend simultaneously the legal, economic and bodily agency of Muslim women. These layered processes of archive-making ultimately invite us to rethink not just Fatima’s story itself but also our current efforts to write gender into global history.
A typology of urban knowledge sharing: from a systematic literature review to an integrated model
Authors: Bakker Jet , Scholten Peter , Fransen Jan , Minkman Ellen 
Published: April 2024

Abstract
This paper provides insight into how the conceptualization of urban knowledge sharing has developed. Based on a structured review and categorization of the literature, we identify three forms of knowledge sharing in and between cities that are distinctly different: knowledge transfer, knowledge exchange, and knowledge co-creation. We find that the three forms have different boosts and barriers, whereby the complexities of knowledge sharing and hence the capacities required of the actors are lowest for knowledge transfer and highest for knowledge co-creation. We would therefore like to qualify the recent emphasis given in literature to co-creation; with its complexities and required capacities, it is not to be considered a panacea for solving all urban problems. We propose a model within which knowledge transfer and exchange are more suitable for less wicked problems and may sometimes fruitfully reduce complexities.
The effects of fasting compared to eating a meal or snack during simulated night shift on changes in metabolism associated with circadian misalignment: a protocol and methods paper
Authors: Yates Crystal L , Centofanti Stephanie , Heilbronn Leonie , Kennaway David , Coates Alison M , Dorrian Jillian , Wittert Gary , Gupta Charlotte C , Stepien Jacqueline M , Catcheside Peter , Banks Siobhan 
Published: April 2024

Abstract

Study Objectives
This protocol paper outlines the methods that will be used to examine the impact of altering meal timing on metabolism, cognitive performance, and mood during the simulated night shift.

Methods
Participants (male and female) will be recruited according to an a priori selected sample size to complete a 7-day within and between participant’s laboratory protocol. Participants will be randomly assigned to one of the three conditions: meal at night or snack at night or no meal at night. This protocol includes an 8-hour nighttime baseline sleep, followed by 4 consecutive nights of simulated nightshift (7 hours day sleep; 10:00–17:00 hours), and an 8-hour nighttime sleep (return to dayshift). During the simulated night shift, meals will be provided at ~06:30, 09:30, 14:10, and 19:00 hours (no eating at night); ~06:30, 19:00, and 00:30 hours (meal at night); or ~06:30, 14:10, 19:00, and 00:30 hours (snack at night). Meal composition will be strictly controlled throughout the study (45%–65% carbohydrates, 15%–25% protein, and 20%–35% fat per day) with daily energy provided to meet individual needs using the Harris-Benedict equation (light/sedentary activity). The primary outcome measures are serum concentrations of blood glucose, insulin, and free fatty acids area under the curve in response to the oral glucose tolerance test. Mixed-effect ANOVAs will be conducted.

Conclusions
This protocol paper describes a methodology to describe an innovative approach to reduce the metabolic disease impact associated with shift work.
Thyroid diseases and female sexual dysfunctions
Authors: Barbagallo Federica , Cannarella Rossella , Condorelli Rosita A , Cucinella Laura , La Vignera Sandro , Nappi Rossella E , Calogero Aldo E 
Published: April 2024

Abstract

Introduction
Female sexual dysfunctions (FSDs) have received little attention in the context of thyroid diseases, despite the high prevalence of both conditions.

Objectives
This review aims to update and summarize the state of knowledge on the association between thyroid diseases and FSDs and to investigate the complex mechanisms through which thyroid hormone imbalance can impact female sexual health in the context of the biopsychosocial model.

Methods
A comprehensive literature search was performed through the PubMed, MEDLINE, and Scopus databases, using the following keywords: “female sexual function,” “sexual dysfunction,” “hypoactive sexual desire disorder,” “thyroid disease,” “thyroiditis,” “hypothyroidism,” and “hyperthyroidism.”

Results
To date, well-designed studies that describe the relationship between FSDs and thyroid disorders are lacking. However, despite the limitations on available studies, current data indicate that sexual alterations are frequently associated with thyroid diseases in women. A complex interplay of direct and indirect hormonal and nonhormonal mechanisms has been hypothesized, including hormonal changes, neurotransmitter imbalance, reduced nitric oxide release, mood disorders, and other systemic consequences of both hypothyroidism and hyperthyroidism. Thyroid hormone receptors have also been identified in the genitourinary system.

Conclusions
In a clinical setting, physicians should investigate the sexuality of patients consulting for thyroid disease. At the same time, an evaluation of thyroid function should be performed in patients presenting with FSD, especially after menopause, when the risk of thyroid diseases and FSDs increases strongly.
Predicting fat cover in beef cattle to make on-farm management decisions: a review of assessing fat and of modeling fat deposition
Authors: McPhee Malcolm J 
Published: April 2024

Abstract
Demands of domestic and foreign market specifications of carcass weight and fat cover, of beef cattle, have led to the development of cattle growth models that predict fat cover to assist on-farm managers make management decisions. The objectives of this paper are 4-fold: 1) conduct a brief review of the biological basis of adipose tissue accretion, 2) briefly review live and carcass assessments of beef cattle, and carcass grading systems used to develop quantitative compositional and quality indices, 3) review fat deposition models: Davis growth model (DGM), French National Institute for Agricultural Research growth model (IGM), Cornell Value Discovery System (CVDS), and BeefSpecs drafting tool (BeefSpecsDT), and 4) appraise the process of translating science and practical skills into research/decision support tools that assist the Beef industry improve profitability. The r2 for live and carcass animal assessments, using several techniques across a range of species and traits, ranged from 0.61 to 0.99 and from 0.52 to 0.99, respectively. Model evaluations of DGM and IGM were conducted using Salers heifers (n = 24) and Angus-Hereford steers (n = 15) from an existing publication and model evaluations of CVDS and BeefSpecsDT were conducted using Angus steers (n = 33) from a research trial where steers were grain finished for 101 d in a commercial feedlot. Evaluating the observed and predicted fat mass (FM) is the focus of this review. The FM mean bias for Salers heifers were 7.5 and 1.3 kg and the root mean square error of prediction (RMSEP) were 31.2 and 27.8 kg and for Angus-Hereford steers the mean bias were −4.0 and −10.5 kg and the RMSEP were 9.14 and 21.5 kg for DGM and IGM, respectively. The FM mean bias for Angus steers were −5.61 and −2.93 kg and the RMSEP were 12.3 and 13.4 kg for CVDS and BeefSpecsDT, respectively. The decomposition for bias, slope, and deviance were 21%, 12%, and 68% and 5%, 4%, and 91% for CVDS and BeefSpecsDT, respectively. The modeling efficiencies were 0.38 and 0.27 and the models were within a 20 kg level of tolerance 91% and 88% for CVDS and BeefSpecsDT, respectively. Fat deposition models reported in this review have the potential to assist the beef industry make on-farm management decisions on live cattle before slaughter and improve profitability. Modelers need to continually assess and improve their models but with a caveat of 1) striving to minimize inputs, and 2) choosing on-farm inputs that are readily available.