bluuebunny/crossref_metadata_2025_split huggingface dataset:
Cognitive load, social values and financial distress: drivers of restructuring decisions
Authors: Balume Fidèle Shukuru , Gajewski Jean-François , Heimann Marco 
Published: April 2024

Purpose
This study aims to analyze the effect of cognitive load and social value orientation on managers’ preferences when they face with two types of restructuring choices in financially distressed firms: the first belonging to the family of organizational restructuring (massive layoffs) and the second to the family of financial restructuring (debt increases).

Design/methodology/approach
The authors investigate experimentally the impact of managers’ cognitive load and social value orientation on the decision to restructure leveraged buyout (LBO) firms in financial distress by using either massive layoffs or debt increases.

Findings
By investigating the impact of managers’ cognitive load and social value orientation on the restructuring decision of an LBO firm in financial distress, the research reveals that, on average, cognitively loaded managers prefer massive layoffs over increased debt levels. The massive layoffs seemingly provide a relatively easier way to avoid conflict with influential, residual claimants. In contrast, social value–oriented managers actively avoid massive layoffs and prefer to increase debt.

Research limitations/implications
These results imply that the performance mechanisms emphasized to improve agency relations, for example, in LBOs, have their own limitations during periods of financial distress. This study shows that one of these limits is related to cognitive distortions and personality traits.

Originality/value
In this research, the originality lies in understanding how managers’ internal factors affect their restructuring decision-making, in the case of LBO firms in financial distress.
Unleashing synergy: exploring the impact of experiential learning and component technology on integration implementation strategy in cross-border technological acquisitions
Authors: Hanif Nadia 
Published: April 2024

Purpose
Drawing on organizational design theory and organizational learning theory, this paper aims to examine component technology (CT) and the interaction between CT and experiential learning (EL) effects on the degree of integration (DI) of cross-border technological acquisitions.

Design/methodology/approach
Using a sample of 267 firms consisting of 229 acquirer firms who started cross-border technological acquisitions from developed economies and 38 acquirer firms who initiated cross-border technological acquisitions from emerging economies over the period of 1993–2016, this study adopts a value chain framework to measure the acquirers’ acquisition integration degree for the investigation of the effects of CT and the interaction between CT and EL.

Findings
First, this paper finds CT in cross-border technological acquisitions exerting a positive influence on the acquirer firm’s likelihood of the DI implementation, in line with the organizational design theory. Second, in view of organizational learning theory, this study finds EL and the combined effect of CT and EL to have an inverse influence on the DI.

Practical implications
The results imply that the moderating role of EL significantly optimizes decision choices for an acquirer firm for integration implementation strategies in the form of DI, such as full integration (structural integration), partial integration and no integration (structural separation), which appears to be crucial for cross-border technological acquisitions.

Originality/value
This study contributed to international business strategies by shedding light on the importance of the DI for an acquirer firm that undertakes a cross-border technological acquisition with a CT target firm. This study explains why structural integration might be necessary in cross-border technological acquisitions regardless of the costs of disruption it imposes, as well as the contexts in which it becomes less important or unnecessary. The study disclosed that the increase in the likelihood of DI because of CT depends on the EL of the acquisition company in the host country environment and fluctuates with the prior acquisition knowledge and EL of the host country. Combining two cross-border technological acquisition’s literature streams, such as CT and EL, this study enlightens the importance of organizational learning theory and theory of organization design strategic direction making on acquisition integration implementation strategies.
Female digital nomads’ destination experiencescape perspective
Authors: Özoğul Balyali Tuğçe 
Published: April 2024

PurposeAlthough existing studies provide valuable insight into how destinations create stimuli that support meaningful experiences, perceptions of different experiencescapes in the tourism context remain to be explored. This research aims to explore the experiencescape stimuli of female digital nomads.Design/methodology/approachThe study adopted a qualitative research method and was structured by combining multiple qualitative data collection tools with a triangulated approach to examining the experiencescape.FindingsBased on the experiences of female digital nomads toward destinations, their perception of the experiencescape, which includes sensory, functional, social, natural and cultural stimuli, has been revealed. From the explanations regarding the metaphors, the female digital nomads in the research have positive perceptions about destination experiences and are satisfied with being digital nomads.Research limitations/implicationsThe fact that the research is the first to focus on digital nomadism and experiencescape and that it reveals the perspective of female digital nomads who share their experiences in virtual communities, which is a research topic that is little emphasized in the literature, is a contribution to the theoretical framework on the subject. The practical contribution is that it will guide studies to improve and re-plan experiences in line with the stimuli emphasized by the female digital nomads studied. The results can play a supporting role in developing the market for female digital nomads.Originality/valueThis research offers a new perspective on exploring female digital nomads' perceptions of the destination experiencescape.
The business case for hospital mobility programs in the veterans health care system: Results from multi‐hospital implementation of the STRIDE program
Authors: Kaufman Brystana G. , Hastings S. Nicole , Meyer Cassie , Stechuchak Karen M. , Choate Ashley , Decosimo Kasey , Sullivan Caitlin , Wang Virginia , Allen Kelli D. , Van Houtven Courtney H. 
Published: April 2024

AbstractObjectiveTo conduct a business case analysis for Department of Veterans Affairs (VA) program STRIDE (ASsisTed EaRly MobIlization for hospitalizeD older VEterans), which was designed to address immobility for hospitalized older adults.Data Sources and Study SettingThis was a secondary analysis of primary data from a VA 8‐hospital implementation trial conducted by the Function and Independence Quality Enhancement Research Initiative (QUERI). In partnership with VA operational partners, we estimated resources needed for program delivery in and out of the VA as well as national implementation facilitation in the VA. A scenario analysis using wage data from the Bureau of Labor Statistics informs implementation decisions outside the VA.Study DesignThis budget impact analysis compared delivery and implementation costs for two implementation strategies (Replicating Effective Programs [REP]+CONNECT and REP‐only). To simulate national budget scenarios for implementation, we estimated the number of eligible hospitalizations nationally and varied key parameters (e.g., enrollment rates) to evaluate the impact of uncertainty.Data CollectionPersonnel time and implementation outcomes were collected from hospitals (2017–2019). Hospital average daily census and wage data were estimated as of 2022 to improve relevance to future implementation.Principal FindingsAverage implementation costs were $9450 for REP+CONNECT and $5622 for REP‐only; average program delivery costs were less than $30 per participant in both VA and non‐VA hospital settings. Number of walks had the most impact on delivery costs and ranged from 1 to 5 walks per participant. In sensitivity analyses, cost increased to $35 per participant if a physical therapist assistant conducts the walks. Among study hospitals, mean enrollment rates were higher among the REP+CONNECT hospitals (12%) than the REP‐only hospitals (4%) and VA implementation costs ranged from $66 to $100 per enrolled.ConclusionsSTRIDE is a low‐cost intervention, and program participation has the biggest impact on the resources needed for delivering STRIDE.Trial RegistrationClinicalsTrials.gov NCT03300336. Prospectively registered on 3 October 2017.
Can information constraints explain the low efficiency in premium quality rice cultivation? Evidence from smallholder farmers in Bangladesh
Authors: Kubitza Christoph , Veettil Prakashan Chellattan , Gupta Ishika , Krupnik Timothy J. 
Published: April 2024

AbstractThe integration of smallholder farmers into emerging value chains for fine‐grain and aromatic ‘premium quality rice’ (PQR) could prove to be crucial to improving rural livelihoods in Bangladesh, though efforts could be constrained by farmers' differing levels of agronomic knowledge. Based on a pre‐analysis plan, we analyse farmers' ability to efficiently allocate production enhancing inputs in PQR cultivation based on a survey of 1420 farmers in key PQR producing areas. Farmers received a hypothetical budget to allocate to six different inputs advised for efficient production of PQR, mimicking familiar production decisions made seasonally on their own farms. Our results suggest that even without budget or input access constraints farmers tend to inefficiently allocate inputs in PQR in this hypothetical setting. In particular, they tend to overspend on seeds, fertiliser and pesticides. Farmers with better access to agricultural information, such as through PQR specific extension services, conversely reach substantially higher efficiency scores and decided to spend significantly less on fertiliser. Without future adjustments such as more targeted extension services, implied higher production costs will likely lower the profitability of PQR cultivation for smallholder farmers, thereby limiting potential income gains. Besides these economic concerns, excessive input use is associated with environmental externalities. Improved efficiency is therefore desirable from both an economic and environmental standpoint.
The application of systematic accident analysis tools to investigate food safety incidents
Authors: Oleo Dileyni Díaz De , Manning Louise , McIntyre Lynn , Randall Nicola , Nayak Rounaq 
Published: April 2024

AbstractEffective food safety (FS) management relies on the understanding of the factors that contribute to FS incidents (FSIs) and the means for their mitigation and control. This review aims to explore the application of systematic accident analysis tools to both design FS management systems (FSMSs) as well as to investigate FSI to identify contributive and causative factors associated with FSI and the means for their elimination or control. The study has compared and contrasted the diverse characteristics of linear, epidemiological, and systematic accident analysis tools and hazard analysis critical control point (HACCP) and the types and depth of qualitative and quantitative analysis they promote. Systematic accident analysis tools, such as the Accident Map Model, the Functional Resonance Accident Model, or the Systems Theoretical Accident Model and Processes, are flexible systematic approaches to analyzing FSI within a socio‐technical food system which is complex and continually evolving. They can be applied at organizational, supply chain, or wider food system levels. As with the application of HACCP principles, the process is time‐consuming and requires skilled users to achieve the level of systematic analysis required to ensure effective validation and verification of FSMS and revalidation and reverification following an FSI. Effective revalidation and reverification are essential to prevent recurrent FSI and to inform new practices and processes for emergent FS concerns and the means for their control.
Identification of phenolic compounds from fermented Moringa oleifera Lam. leaf supplemented with Fuzhuan brick tea and their volatile composition and anti‐obesity activity
Authors: Li Xin , Han Haoyue , Ma Ying , Wang Xin , Lü Xin 
Published: April 2024

AbstractAs a nutritious plant with valuable potential, the Moringa oleifera Lam. (MOL) leaf addition on Fuzhuan brick tea (FBT) for the co‐fermentation (MOL‐FBT) was an industry innovation and a new route to make full use of MOL leaf. After optimization of the extraction conditions, the best conditions for the polyphenols extraction method from MOL‐FBT (MFP) were 60°C for 40 min (1:80, V/W) using response surface methodology. A total of 30 phenolics were identified and quantified. Most of the polyphenols were increased after adding MOL leaf for co‐fermentation compared to FBT polyphenols. In particular, caffeic acids were found only in MFP. Moreover, the MFP received high value in taste, aroma, and color. In total, 62 volatile flavor compounds, consisting of 3 acids, 5 alcohols, 15 aldehydes, 4 esters, 20 hydrocarbons, 10 ketones, and 5 others, were identified in MFP. In addition, MFP inhibited 3T3‐L1 preadipocyte differentiation in a dose‐dependent manner and decreased lipid accumulation via the peroxisome proliferator‐activated receptor gamma (PPARγ)/CCAAT/enhancer binding protein alpha (CEBPα)/cluster of differentiation 36 (CD36) axis and induced a brown adipocyte‐like phenotype. In vivo experiments were further conducted to confirm the in vitro results. MFP regulated lipid accumulation, glucose/insulin tolerance, improved liver and kidney function, and inhibited the secretion of pro‐inflammatory factors by the PPARγ/CEBPα/CD36 axis and alleviated inflammation in high fat and high fructose diet‐induced obese mice. In summary, MFP possesses high‐quality properties and anti‐obesity effects, as well as the great potential to be used as a novel functional food product.
Current state of theranostics in metastatic castrate‐resistant prostate cancer
Authors: Nindra Udit , Lin Peter , Becker Therese , Roberts Tara L , Chua Wei 
Published: April 2024

SummaryProstate cancer remains one of the leading causes of cancer‐related death in the world. There have been significant advances in chemotherapy, hormonal therapy and targeted therapy options for patients with castrate‐resistant disease. However, these systemic treatments are often associated with unwanted toxicities. Targeted therapy with radiopharmaceuticals has become of key interest to limit systemic toxicity and provides a more precision oncology approach to treatment. Strontium‐89, Samarium‐153 EDTMP and Radium‐223 have been trialled with mixed results. Strontium‐89 and Samarium‐153 EDTMP have shown benefits in palliating metastatic bone pain but with no impact on survival outcomes. Early therapeutic radiopharmaceuticals targeting PSMA that were developed were beta‐emitting agents, but recently alpha‐emitting agents are being investigated as potentially superior options. Radium‐223 is the first alpha‐particle emitter therapeutic agent approved by the FDA, with phase III trial evidence showing benefits in overall survival and delay in symptomatic skeletal events for patients. Recently, 177‐Lutetium‐PSMA‐617 has demonstrated significant survival advantages in pre‐treated metastatic castrate‐resistant cancer patients in a number of phase II and III studies. Furthermore, 225‐Actinium‐PSMA‐617 also showed promise even in patients pre‐treated with 177‐Lutetium‐PSMA‐617. Hence, there has been an explosion of radiopharmaceutical treatment options for patients with prostate cancer. This review explores past and current theranostic capacities in the radiopharmaceutical treatment of metastatic castrate‐resistant prostate cancer.
Developing an improved lure for attracting the pine sawyer beetle (Monochamus galloprovincialis) with reduced bycatch of predatory beetles
Authors: Rudziński Krzysztof J. , Sukovata Lidia , Asztemborska Monika , Wróblewska Aleksandra , Nestorowicz Klara , Szmigielski Rafał 
Published: April 2024

Abstract
The pine sawyer beetle (Monochamus galloprovincialis) is a European vector of the invasive pinewood nematode (Bursaphelenchus xylophilus), one of the most dangerous threats to pine forests worldwide. One recommended method for detecting the nematode is catching and inspecting the M. galloprovincialis beetles. Effective commercial lures are available for that insect but attract non‐target species, particularly beneficial Thanasimus species. Our study aimed to develop an equally effective M. galloprovincialis lure less attractive to beneficial predatory insects.
We used electroantennography to test several compounds occurring in the pheromones, hindgut extracts or headspace emissions of non‐Ips bark beetles. The compounds that caused the strongest antennal responses were used along with α‐pinene (host‐tree volatile) and monochamol (2‐undecyloxy‐1‐ethanol, a male‐produced aggregation pheromone of M. galloprovincialis) to prepare the lures for olfactometric and field testing.
In the field experiments, the lure containing (+)‐α‐pinene, monochamol, (1R)‐(−)‐myrtenal and (S)‐(−)‐trans‐verbenol was equally effective as the commercial lure Galloprotect Pack. It attracted significantly less Thanasimus formicarius and T. femoralis beetles.
Thus, the new lure can serve as a basis for developing an operational lure for monitoring M. galloprovincialis with reduced bycatch of predatory beetles.
The first International Association of Diabetes and Pregnancy Study Groups summit on the diagnosis of gestational diabetes in early pregnancy: TOBOGM Summit Report
Authors: Sweeting Arianne , MacMillan Freya , Simmons David ,   for the TOBOGM Summit attendees
Published: April 2024

AbstractThe first International Association of Diabetes and Pregnancy Study Groups Summit on the diagnosis of gestational diabetes in early pregnancy (Treatment of Booking Gestational Diabetes Mellitus (TOBOGM) Summit) was held on the 17 November 2022 in Sydney, Australia. It sought to use the TOBOGM trial findings to scope the issues involved with early screening, to inform future discussions over possible approaches for diagnosing gestational diabetes mellitus (GDM) in early pregnancy. Most delegates supported testing for early GDM using a one‐step 75 g oral glucose tolerance test approach with Canadian Diabetes Association criteria preferred, but highlighted the importance of considering resources, cost, consumer perspectives and equity in translating TOBOGM results into a clinical approach to screening for, and diagnosing, early GDM.
Lin−CD117+CD34+FcεRI+ progenitor cells are increased in chronic spontaneous urticaria and predict clinical responsiveness to anti‐IgE therapy
Authors: Ridge Katie , Moran Barry , Alvarado‐Vazquez P. Abigail , Hallgren Jenny , Little Mark A. , Irvine Alan D. , O'Farrelly Cliona , Dunne Jean , Finlay Conor M. , Conlon Niall 
Published: April 2024

AbstractBackgroundChronic spontaneous urticaria (CSU) is a common, debilitating skin disorder characterized by recurring episodes of raised, itchy and sometimes painful wheals lasting longer than 6 weeks. CSU is mediated by mast cells which are absent from peripheral blood. However, lineage−CD34hiCD117int/hiFcεRI+ cells in blood have previously been shown to represent a mast cell precursor.MethodsWe enumerated FcεRI−, FcεRI+ and FcεRIhi lineage−CD34+CD117+ cells using flow cytometry in blood of patients with CSU (n = 55), including 12 patients receiving omalizumab and 43 not receiving omalizumab (n = 43). Twenty‐two control samples were studied. Disease control and patient response to omalizumab was evaluated using the urticaria control test. We performed single‐cell RNA sequencing (scRNA‐Seq) on lineage−CD34hiCD117hi blood cells from a subset of patients with CSU (n = 8) and healthy controls (n = 4).ResultsCSU patients had more lineage−CD34+CD117+FcεRI+ blood cells than controls. Lineage−CD34+CD117+FcεRI+ cells were significantly higher in patients with CSU who had an objective clinical response to omalizumab when compared to patients who had poor disease control 90 days after initiation of omalizumab. scRNA‐Seq revealed that lineage−CD34+CD117+FcεRI+ cells contained both lymphoid and myeloid progenitor lineages, with omalizumab responsive patients having proportionally more myeloid progenitors. The myeloid progenitor lineage contained small numbers of true mast cell precursors along with more immature FcεRI− and FcεRI+ myeloid progenitors.ConclusionIncreased blood CD34+CD117+FcεRI+ cells may reflect enhanced bone marrow egress in the setting of CSU. High expression of these cells strongly predicts better clinical responses to the anti‐IgE therapy, omalizumab.
Child sexual abuse and social identity loss: A qualitative analysis of survivors' public accounts
Authors: Muldoon Orla T. , Nightingale Alastair , McMahon Grace , Griffin Siobhan , Bradshaw Daragh , Lowe Robert D. , McLaughlin Katrina 
Published: April 2024

AbstractEmerging evidence suggests that social identities are an important determinant of adaptation following traumatic life experiences. In this paper, we analyse accounts of people who experienced child sexual abuse. Using publicly available talk of people who waived their right to anonymity following successful conviction of perpetrators, we conducted a thematic analysis focusing on trauma‐related changes in their social identities. Analysis of these accounts highlighted two themes. The first highlights the acquisition in these accounts of unwanted and damaging identity labels. The second presents child sexual abuse as a key destructive force in terms of important identity work during childhood. Discussion of this analysis centres on the pathological consequences of social identity change. Both the loss of valued identities and the acquisition of aberrant and isolating identities are experienced and constructed as devastating by those affected by child sexual abuse. This has important implications, not only for those impacted by child sexual abuse but for how abuse is discussed in society, and how it is approached by policy makers, educators and individuals working with survivors and their families.