bluuebunny/crossref_metadata_2025_split huggingface dataset:
Wireless Pulmonary Artery Pressure Monitor Implantation in a Patient with Duchenne Muscular Dystrophy
Authors: Sisson T. Miller , Sublett-Smith Juli , Dupont Elizabeth , Hirsch Russel , Lorts Angela , Villa Chet 
Published: March 2024

AbstractAssessing heart failure progression in patients with Duchenne Muscular Dystrophy (DMD) is challenging given the multi-system nature of disease. Herein we describe the first case use of an implantable pulmonary artery pressure monitor and describe the potential clinical utility of this approach in patients with DMD.
Perinatal arterial ischemic stroke: how informative is the placenta?
Authors: Hirschel Jessica , Barcos-Munoz Francisca , Chalard François , Chiodini Florence , Epiney Manuella , Fluss Joel , Rougemont Anne-Laure 
Published: March 2024

AbstractNeuroplacentology is an expanding field of interest that addresses the placental influence on fetal and neonatal brain lesions and on further neurodevelopment. The objective of this study was to clarify the link between placental pathology and perinatal arterial ischemic stroke (PAIS). Prior publications have reported different types of perinatal stroke with diverse methodologies precluding firm conclusions. We report here the histological placental findings in a series of 16 neonates with radiologically confirmed PAIS. Findings were grouped into 3 categories of lesions: (1) inflammation, (2) placental and fetal hypoxic lesions, and (3) placentas with a high birthweight/placenta weight ratio. Matched control placentas were compared to the pathological placentas when feasible. The eight term singleton placentas were compared to a series of 20 placentas from a highly controlled amniotic membrane donation program; in three twin pregnancies, the placental portions from the affected twin and unaffected co-twin were compared. Slightly more than half (9/16, 56%) had histopathological features belonging to more than one category, a feature shared by the singleton control placentas (13/20, 65%). More severe and extensive lesions were however observed in the pathological placentas. One case occurring in the context of SARS-CoV-2 placentitis further expands the spectrum of COVID-related perinatal disease. Our study supports the assumption that PAIS can result from various combinations and interplay of maternal and fetal factors and confirms the value of placenta examination. Yet, placental findings must be interpreted with caution given their prevalence in well-designed controls.
Screening/diagnosis of pediatric endocrine disorders through the artificial intelligence model in different language settings
Authors: Ying Lingwen , Li Sichen , Chen Chunyang , Yang Fan , Li Xin , Chen Yao , Ding Yu , Chang Guoying , Li Juan , Wang Xiumin 
Published: March 2024

AbstractThis study is aimed at examining the impact of ChatGPT on pediatric endocrine and metabolic conditions, particularly in the areas of screening and diagnosis, in both Chinese and English modes. A 40-question questionnaire covering the four most common pediatric endocrine and metabolic conditions was posed to ChatGPT in both Chinese and English three times each. Six pediatric endocrinologists evaluated the responses. ChatGPT performed better when responding to questions in English, with an unreliable rate of 7.5% compared to 27.5% for Chinese questions, indicating a more consistent response pattern in English. Among the reliable questions, the answers were more comprehensive and satisfactory in the English mode. We also found disparities in ChatGPT’s performance when interacting with different target groups and diseases, with improved performance for questions posed by clinicians in English and better performance for questions related to diabetes and overweight/obesity in Chinese for both clinicians and patients. Language comprehension, providing incomprehensive answers, and errors in key data were the main contributors to the low scores, according to reviewer feedback.Conclusion: Despite these limitations, as ChatGPT continues to evolve and expand its network, it has significant potential as a practical and effective tool for clinical diagnosis and treatment.

What is Known:• The deep learning-based large-language model ChatGPT holds great promise for improving clinical practice for both physicians and patients and has the potential to increase the speed and accuracy of disease screening and diagnosis, as well as enhance the overall efficiency of the medical process. However, the reliability and appropriateness of AI model responses in specific field remains unclear.• This study focused on the reliability and appropriateness of AI model responses to straightforward and fundamental questions related to the four most prevalent pediatric endocrine and metabolic disorders, for both healthcare providers and patients, in different language scenarios.

What is New:• The AI model performed better when responding to questions in English, with more consistent, as well as more comprehensive and satisfactory responses. In addition, we also found disparities in ChatGPT’s performance when interacting with different target groups and different diseases.• Despite these limitations, as ChatGPT continues to evolve and expand its network, it has significant potential as a practical and effective tool for clinical diagnosis and treatment.
VR interventions aimed to induce empathy: a scoping review
Authors: Trevena Lee , Paay Jeni , McDonald Rachael 
Published: March 2024

AbstractTo assess the methods and outcomes of virtual reality (VR), interventions aimed at inducing empathy and to evaluate if VR could be used in this manner for disability support worker (DSW) training, as well as highlight areas for future research. The authors conducted a scoping review of studies that used VR interventions to induce empathy in participants. We searched three databases for articles published between 1960 and 2021 using “virtual reality” and “empathy” as key terms. The search yielded 707 articles, and 44 were reviewed. VR interventions largely resulted in enhanced empathy skills for participants. Most studies agreed that VR’s ability to facilitate perspective-taking was key to inducing empathy for participants. Samples were often limited to the context of healthcare, medicine, and education. This literature provides preliminary evidence for the technology’s efficacy for inducing empathy. Identified research gaps relate to limited studies done, study quality and design, best practice intervention characteristics, populations and outcomes of interest, including lack of transfer and data across real-world settings.
Rechtliche Aspekte von schwimmenden Photovoltaikanlagen
Authors: Weber Max 
Published: March 2024

ZusammenfassungDas nordrhein-westfälische Wirtschaftsministerium sieht im Ausbau von schwimmende Photovoltaikanlagen
(oder Floating-PV) einen “wichtigen Baustein”, um die Ausbauziele für die Erneuerbaren
Energien in Nordrhein-Westfalen und auf Bundesebene zu erreichen. Die Nutzung erneuerbarer Energien ist
von zentraler Bedeutung im globalen Bemühen, den Klimawandel einzudämmen. Schwimmende Photovoltaikanlagen,
auch bekannt als Solarinseln, stellen eine innovative Technologie dar, die die Energiegewinnung auf Gewässern
ermöglicht. Dieser Beitrag widmet sich den rechtlichen Fragestellungen und Problemen, die im Zusammenhang
mit der Errichtung von schwimmenden Photovoltaikanlagen auftreten können. Neben dem Bundesrecht dabei
insbesondere das nordrhein-westfälische Landesrecht behandelt.
The Liar Paradox: A Case of Mistaken Truth Attribution
Authors: Doomen Jasper 
Published: March 2024

AbstractA semantic solution to the liar paradox (“This statement is not true”) is presented in this article. Since the liar paradox seems to evince a contradiction, the principle of non-contradiction is preliminarily discussed, in order to determine whether dismissing this principle may be reason enough to stop considering the liar paradox a problem. No conclusive outcome with respect to the value of this principle is aspired to here, so that the inquiry is not concluded at this point and the option to explore an alternative, semantic, solution remains open. This proposed solution is focused on what the liar paradox expresses and what it fails to express.
On the discrepancies between POD and Fourier modes on aperiodic domains
Authors: Hodžić Azur , Olesen Peder J. , Velte Clara M. 
Published: March 2024

AbstractThe application of Fourier analysis in combination with the Proper Orthogonal Decomposition (POD) is investigated. In this approach to turbulence decomposition, which has recently been termed Spectral POD (SPOD), Fourier modes are considered as solutions to the corresponding Fredholm integral equation of the second kind along homogeneous-periodic or homogeneous coordinates. In the present work, the notion that the POD modes formally converge to Fourier modes for increasing domain length is challenged. A family of analytical correlation functions parametrized by the Taylor macro/micro scale ratio (MMSR) is investigated numerically. The results of the analysis indicate that the discrepancy between POD and Fourier modes along locally translationally invariant coordinates is coupled to the MMSR of the flow. Increasing discrepancies are observed for smaller MMSRs, which are characteristic of low Reynolds number flows. The asymptotic convergence rate of the eigenspectrum matches the corresponding convergence rate of the exact analytical Fourier spectrum of the kernel in question, even for extremely small domains and small MMSRs where the corresponding DFT spectra suffer heavily from windowing effects. The Taylor micro scales are consistently underestimated when reconstructed using Fourier modes—failing to converge to the correct value even if all Fourier modes are used—while these are accurately reconstructed using POD modes.
Partnership Dynamics of LGB People and Heterosexuals: Patterns of First Partnership Formation and First Cohabitation
Authors: Bohr Jeanette , Lengerer Andrea 
Published: March 2024

Abstract
In this study we examine partnership dynamics among people with different sexual orientations in Germany. More specifically, we explore the process of first partnership formation and first cohabitation among men and women who self-identify as heterosexual, homosexual or bisexual. Given the various discriminations against same-sex lifestyles, and the limited opportunities to meet potential partners, we assume that lesbian, gay and bisexual (LGB) people form partnerships later in life and less frequently than heterosexuals. We further expect that the constantly improving social and legal climate for sexual minorities will lead to a reduction in differences in partnership behaviour by sexual orientation. We use retrospectively reported partnership biographies from the German Socio-Economic Panel, which was supplemented in 2019 with a boost sample of sexual and gender minority households. Using discrete-time event history models, we analyse nearly 15,000 episodes of being single and nearly 20,000 episodes of living without a partner in the household. Around 4.5% of these episodes are from people who self-identify as LGB. The results clearly show that patterns of partnership and coresidential union formation differ by sexual orientation. People with a homosexual orientation—and to a lesser extent people with a bisexual orientation—are less likely to enter into a first partnership and a first cohabitation than people with a heterosexual orientation. Significant changes occur across cohorts: LGB people from younger birth cohorts enter (cohabiting) partnerships much earlier and more frequently than those from older cohorts. Thus, the union formation patterns of LGB and straight people have converged slightly.
Gender and National Collective Narcissism: Gender Asymmetries and Obstacles to Gender Equality
Authors: Golec de Zavala Agnieszka , Keenan Oliver 
Published: March 2024

AbstractTo elucidate how ingroup identification is implicated in attitudes towards gender equality, it is important to consider that (1) people simultaneously identify with more (a nation) vs. less abstract groups (gender), and (2) gender collective narcissism is the specific aspect of ingroup identification likely to inspire opposite attitudes towards gender equality among men (negative) and women (positive), but (3) national narcissism is likely to align with men’s interests and inspire negative attitudes towards gender equality among men and women. In Study 1, we demonstrate that gender collective narcissism is the same variable among men and women. In Study 2, we show that among women (but not among men) in Poland, gender collective narcissism predicts intentions to engage in normative and non-normative collective action for gender equality. In Study 3, we show that gender collective narcissists among women endorse an egalitarian outlook, whereas gender collective narcissists among men reject it. In contrast, national narcissism predicts refusal to engage in collective action for gender equality and endorsement of an anti-egalitarian outlook among women and among men. Thus, national narcissism and gender collective narcissism among men impair pursuit of gender equality. Gender collective narcissism among women facilitates engagement in collective action for gender equality. Low gender collective narcissism among men and low national narcissism may also facilitate support for gender equality.
A constant-per-iteration likelihood ratio test for online changepoint detection for exponential family models
Authors: Ward Kes , Romano Gaetano , Eckley Idris , Fearnhead Paul 
Published: March 2024

AbstractOnline changepoint detection algorithms that are based on (generalised) likelihood-ratio tests have been shown to have excellent statistical properties. However, a simple online implementation is computationally infeasible as, at time T, it involves considering O(T) possible locations for the change. Recently, the FOCuS algorithm has been introduced for detecting changes in mean in Gaussian data that decreases the per-iteration cost to $$O(\log T)$$

O
(
log
T
)

. This is possible by using pruning ideas, which reduce the set of changepoint locations that need to be considered at time T to approximately $$\log T$$

log
T

. We show that if one wishes to perform the likelihood ratio test for a different one-parameter exponential family model, then exactly the same pruning rule can be used, and again one need only consider approximately $$\log T$$

log
T

locations at iteration T. Furthermore, we show how we can adaptively perform the maximisation step of the algorithm so that we need only maximise the test statistic over a small subset of these possible locations. Empirical results show that the resulting online algorithm, which can detect changes under a wide range of models, has a constant-per-iteration cost on average.
Toward HPC application portability via C++ PSTL: the Gaia AVU-GSR code assessment
Authors: Malenza Giulio , Cesare Valentina , Aldinucci Marco , Becciani Ugo , Vecchiato Alberto 
Published: March 2024

AbstractThe computing capacity needed to process the data generated in modern scientific experiments is approaching ExaFLOPs. Currently, achieving such performances is only feasible through GPU-accelerated supercomputers. Different languages were developed to program GPUs at different levels of abstraction. Typically, the more abstract the languages, the more portable they are across different GPUs. However, the less abstract and co-designed with the hardware, the more room for code optimization and, eventually, the more performance. In the HPC context, portability and performance are a fairly traditional dichotomy. The current C++ Parallel Standard Template Library (PSTL) has the potential to go beyond this dichotomy. In this work, we analyze the main performance benefits and limitations of PSTL using as a use-case the Gaia Astrometric Verification Unit-Global Sphere Reconstruction parallel solver developed by the European Space Agency Gaia mission. The code aims to find the astrometric parameters of $$\sim10^8$$

∼

10
8

stars in the Milky Way by iteratively solving a linear system of equations with the LSQR algorithm, originally GPU-ported with the CUDA language. We show that the performance obtained with the PSTL version, which is intrinsically more portable than CUDA, is comparable to the CUDA one on NVIDIA GPU architecture.
Joint Attention in Team Sport
Authors: Birse Gordon 
Published: March 2024

AbstractThis paper explores how the phenomenon of Joint Attention (JA) drives certain core features of team sport and how sport illuminates the nature of JA. In JA, two or more agents focus on the same object in mutual awareness that the content of their experience is thus shared. JA is essential to joint sporting actions. The sporting context is particularly useful for illustrating the phenomenon of JA and provides a valuable lens through which to examine rival theoretical accounts of its workings. This paper draws novel connections between the respective philosophical literatures on JA and sport, suggesting prospects for mutually advantageous cross-pollination. I contend that the workings of JA within joint sporting action are misconstrued on intellectualistic and individualistic theories which posit reductive explanations in terms of the contents of individual minds. The best evidence and strongest philosophical arguments support ‘relational’ accounts whereby joint sporting actions exceed the sum of their parts. I reject the ‘extensionalist’ contention, associated with ‘lean’ versions of the relationalist approach, that objects of JA are individuated in terms of causal properties not sensitive to how they are perceived. Siding instead with ‘rich’ versions of the view, I argue that team collaboration depends on convergence in terms of the ‘aspectual shape’ of the objects of JA. Finally, a further possible application for these ideas is suggested: that JA plays a central role in the constitution of sport-specific kinds. On this proposal, JA facilitates collective perceptual recognition of particular objects and situations as embodying the general types described in the rulebook, playing an important role in creating and sustaining the public ‘social space’ of sporting competition.
Oxygen Distribution at the Hot Spot in BOF Steelmaking
Authors: Mitas Bernhard , Schenk Johannes 
Published: March 2024

AbstractThe distribution of oxygen between the gaseous and liquid oxidation products at the hot spot is modeled. The simplified model accurately describes the interaction of the gas jet exiting the lance nozzles with the gaseous surrounding of the jet. This interaction changes the chemical composition of the gas jet influencing the subsequent interaction with the hot spot. The iterative procedure then calculates the chemical composition of the gas exiting the cavity. The characterization of the exiting gas flowing past the lance head as well as the generation rate of FeO is attained by combining the modeled gas composition exiting the cavity with an oxygen mass balance based on a quasi-stationary BOF operation.
Beam deflection coupled systems of fractional differential equations: existence of solutions, Ulam–Hyers stability and travelling waves
Authors: Bensassa Kamel , Dahmani Zoubir , Rakah Mahdi , Sarikaya Mehmet Zeki 
Published: March 2024

AbstractIn this paper, we study a coupled system of beam deflection type that involves nonlinear equations with sequential Caputo fractional derivatives. Under flexible/fixed end-conditions, two main theorems on the existence and uniqueness of solutions are proved by using two fixed point theorems. Some examples are discussed to illustrate the applications of the existence and uniqueness of solution results. Another main result on the Ulam–Hyers stability of solutions for the introduced system is also discussed. Some examples of stability are discussed. New travelling wave solutions are obtained for another conformable coupled system of beam type that has a connection with the first considered system. A conclusion follows at the end.
Multi-dimensional characterization of apoptosis in the tumor microenvironment and therapeutic relevance in melanoma
Authors: Ye Jing , Wei Benliang , Zhou Guowei , Xu Yantao , He Yi , Hu Xiheng , Chen Xiang , Zhang Guanxiong , Liu Hong 
Published: March 2024

Abstract
Purpose
Melanoma is widely utilized as a prominent model for the development of immunotherapy, thought an inadequate immune response can occur. Moreover, the development of apoptosis-related therapies and combinations with other therapeutic strategies is impeded by the limited understanding of apoptosis’s role within diverse tumor immune microenvironments (TMEs).

Methods
Here, we constructed an apoptosis-related tumor microenvironment signature (ATM) and employ multi-dimensional analysis to understand the roles of apoptosis in tumor microenvironment. We further assessed the clinical applications of ATM in nine independent cohorts, and anticipated the impact of ATM on cellular drug response in cultured cells.

Results
Our ATM model exhibits robust performance in survival prediction in multiple melanoma cohorts. Different ATM groups exhibited distinct molecular signatures and biological processes. The low ATM group exhibited significant enrichment in B cell activation-related pathways. What’s more, plasma cells showed the lowest ATM score, highlighting their role as pivotal contributors in the ATM model. Mechanistically, the analysis of the interplay between plasma cells and other immune cells elucidated their crucial role in orchestrating an effective anti-tumor immune response. Significantly, the ATM signature exhibited associations with therapeutic efficacy of immune checkpoint blockade and the drug sensitivity of various agents, including FDA-approved and clinically utilized drugs targeting the VEGF signaling pathway. Finally, ATM was associated with tertiary lymphoid structures (TLS), exhibiting stronger patient stratification ability compared to classical “hot tumors”.

Conclusion
Our findings indicate that ATM is a prognostic factor and is associated with the immune response and drug sensitivity in melanoma.
Canonical notch activation in patients with scrub typhus: association with organ dysfunction and poor outcome
Authors: Damås Jan K. , Otterdal Kari , Astrup Elisabeth , Lekva Tove , Janardhanan Jeshina , Michelsen Annika , Aukrust Pål , Varghese George M. , Ueland Thor 
Published: March 2024

Abstract
Purpose
The mechanisms that control inflammation in scrub typhus are not fully elucidated. The Notch pathways are important regulators of inflammation and infection, but have not been investigated in scrub typhus.

Methods
Plasma levels of the canonical Notch ligand Delta-like protein 1 (DLL1) were measured by enzyme immunoassay and RNA expression of the Notch receptors (NOTCH1, NOTCH2 and NOTCH4) in whole blood was analyzed by real-time PCR in patients with scrub typhus (n = 129), in patients with similar febrile illness without O. tsutsugamushi infection (n = 31) and in healthy controls (n = 31); all from the same area of South India.

Results
Our main results were: (i) plasma DLL1 was markedly increased in scrub typhus patients at hospital admission with a significant decrease during recovery. (ii) RNA expression of NOTCH4 was decreased at admission in whole blood. (iii) A similar pattern for DLL1 and NOTCH4 was seen in febrile disease controls. (iv) Admission DLL1 in plasma was associated with disease severity and short-term survival. (vi) Regulation of Notch pathways in O. tsutsugamushi-infected monocytes as evaluated by public repository data revealed enhanced canonical Notch activation with upregulation of DLL1 and downregulation of NOTCH4.

Conclusion
Our findings suggest that scrub typhus patients are characterized by enhanced canonical Notch activation. Elevated plasma levels of DLL1 were associated with organ dysfunction and poor outcomes in these patients.