bluuebunny/crossref_metadata_2025_split huggingface dataset:
FUNGSI KELOMPOK TANI MEKARSARI DALAM MENINGKATKAN KESEJAHTERAAN ANGGOTA KELOMPOK DI DESA ABADI JAYA KECAMATAN MAGINTI KABUPATEN MUNA BARAT
Authors: Sari Anita , Tawulo Megawati A. , Tanzil Tanzil 
Published: March 2024

Penelitian ini bertujuan untuk mengetahui fungsi kelompok tani Mekarsari dalam meningkatkan kesejahteraan anggota kelompok, di Desa Abadi Jaya Kecamatan Maginti Kabupaten Muna Barat. Metode penelitian yang digunakan dalam penelitian ini yaitu analisis deskriptif kualitatif yang digunakan dalam penelitian ini yaitu analisis informan dipilih dengan menggunakan teknik purposive sampling atau dengan cara disengaja. Hasil penelitian ini menggambarkan Fungsi kelompok tani Mekarsari dalam meningkatkan kesejahteraan anggota kelompok di Desa Abadi Jaya Kecamatan Maginti Kabupaten Muna Barat. kelompok tani Mekarsari menjalankan fungsi yang meliputi adanya Kelas belajar, Wahana kerjasama, dan Unit produksi. Kemudian, Faktor pendukung kelompok tani Mekarsari dalam meningkatkan kesejahteraan anggota kelompok yang berdasarkan tiga hal faktor pendukung yaitu, partisipasi anggota kelompok, dan adanya motovasi anggota. Sedangkan faktor penghambat kelompok tani Mekarsari yaitu: pengairan yang belum memadai petani.
PERAN DINAS SOSIAL TERHADAP ANAK TERLANTAR DI KOTA KENDARI
Authors: Arniyanti Arniyanti , Tanzil Tanzil , Bahtiar Bahtiar 
Published: March 2024

Penelitian bertujuan untuk mengetahui Peran Dinas Sosial Terhadap Anak Terlantar
Di Kota Kendari. Jenis penelitian ini merupakan penelitian deskriptif dengan
pendekatan kualitatif. Sedangkangkan tehnik pengumpulan data yang digunakan
yaitu observasi, wawancara dan dokumentasi. Hasil penelitian ini menyimpulkan
bahwa penanganan terhadap anak terlantar di kota kendari yaitu pelayanan
kelembagaan dan pelayanan masyarakat. Pelayanan kelembagaan yaitu pelayanan
yang dilakukan berbasis kelembagaan untuk memperluas jangkauan pelayanan, dan
pelayanan masyarakat yaitu pelayanan sosial anak terlantar yang dilakukan oleh
kelompok swadaya masyarakat yang telah tumbuh dimasyarakat. Peran dinas sosial
terhadap anak terlantar meliputi: sosialisasi, pendataan, pengendalian sosial,
pemantauan, pengawasan.
The effect of the family environment, school environment, and community environment on students' independence through distance learning
Authors: Anriani Nurul , Asdar Ahsanul Khair , Amiro Tri , Afriadi Bambang , Ernawati Ernawati 
Published: March 2024

This research aimed to investigate the effect of the three education centers on students' independence through distance learning. This study used a quantitative approach using a correlational survey method. This study involved 2263 students from Banten Province, Indonesia, who were selected using random cluster sampling. Research data was collected through independent learning questionnaires and family, school, and community environments. All data were analyzed using multiple linear regression analysis. The results of the descriptive statistical analysis show that the average score of female students' learning independence (96.45) is higher than the average score of male students' learning independence (93.38) through distance learning, and the average junior high school students’ learning independence score (95.81) is higher than the average score of learning independence for high school/equivalent students (93.42) and tertiary institutions (94.21) through distance learning. While the results of inferential statistical testing show that in the implementation of distance learning, (1) the family environment has a significant positive influence on independence learning, (2) the school environment has no significant effect on independence learning, and (3) the community environment has a significant positive effect on learning independence. The findings can have implications for the assessment form in the learning process, which is not only the learning achievement from the content assessment but can also use another form, such as students’ independence, like in these findings.
Violência obstétrica e a importância da atuação da equipe profissional de saúde
Authors: Schuler Maria Fernanda de Lemos , Wenning Gisele Dal , Capingana Isoldina Ngueve Chindemba , Ribeiro Lucas Belani , Campos Thaís Fernandes , De Castro Samara Santos , Fontes Beatriz Pasqueta , Dos Santos Johny William , Gonçalves Maria Beatriz Landim Alves , Savioli Mariana Farias , Prestes Vitor Marques , Souza Amanda Martins , Prestes Lara Ataíde Heyden 
Published: March 2024

Objetivo: Descrever a importância da atuação da equipe profissional de saúde quanto a violência obstétrica. Método: Consiste numa revisão integrativa, realizada com base na seguinte pergunta norteadora: Qual a importância da atuação da equipe profissional de saúde quanto a violência obstétrica? sendo utilizado a estratégia PICO, em que “p” população: Mulheres que sofrem ou sofreram violência obstétrica, “I” interesse: Avaliação da influência da violência obstétrica e atuação da equipe profissional, e “C” e “O” contexto: Impacto da violência obstétrica e importância da equipe profissional de saúde. Utilizou-se a busca avançada por meio da Biblioteca Virtual em Saúde (BVS), cruzando os descritores por meio do operador booleano “AND” e “OR”. Resultados: A amostra final foi constituída de 6 artigos, que resultaram em 2 categorias: Violência obstétrica e os abusos sofridos pelas gestantes; Violência obstétrica e a importância da equipe multiprofissional. Conclusão: Entende-se que, o apoio da equipe multiprofissional é de grande importância durante o atendimento à mulher gestante, deve-se oferecer um suporte integral a mulher e acolhê-la, tendo total conhecimento sobre o significado de violência obstétrica. Conclui-se que a equipe profissional tem um papel crucial quanto a violência obstétrica, no atendimento e na prevenção, o profissional tem de respeitar a mulher e sua fisiologia. Apesar do número elevado de pesquisas sobre o tema abordado, ainda existem muitos profissionais que não sabem o significado de violência obstétrica, no qual traz riscos as gestantes, que necessitam da educação e saúde, os profissionais precisam esta informados sobre o assunto e relatar a gestante que precisa de todo apoio.
Synthesis and antitumor activity of a 2-hydroxy substituted chalcone (C6)
Authors: MUHAMMAD ZAHATU , Ya'u Jamilu , Zezi Abdulqadir , Magaji Muhammad 
Published: March 2024

Cancers account for approximately 13% of all deaths each year with breast cancer being one of the most common. Chemotherapeutic agents used in cancer usually have nonspecific toxicity which kills both tumor and normal cells and cause serious side effects that often limit their efficacy. This study aimed to synthesize chalcone and evaluate its antitumor activity.
Chalcone was synthesized using Claisen-Schmidt condensation and characterized using spectroscopic techniques. The LD50 of the synthesized compound was estimated using OECD-425 guidelines in rats. A mammary tumor was induced with a single subcutaneous administration of 65 mg/kg of 1-methyl nitrosourea (MNU). The rats were palpated weekly to determine the size of the tumor. Eight weeks post MNU administration, the rats were divided into five groups of six rats each and treated with graded doses (12.5, 25, and 50 mg/kg) of the compound and paclitaxel (10 mg/kg) for six weeks. Before treatment, three rats were randomly selected and sacrificed, and mammary gland samples were subjected to histological assessment to confirm the induction of the tumor. At the end of the treatment, the rats were euthanized, and mammary glands were collected and subjected to histological evaluation. The possible mechanism of action of the synthesized compound was elucidated in silico using molecular docking.
The compound was synthesized and named C6. C6 was found to be relatively safe with LD50 above 2000 mg/kg and exhibited remarkable antitumor activity. MNU-induced mammary tumor rats treated with C6 produced a significant decrease in tumor diameter when compared with the untreated group, histology slides displayed fewer signs of hyperplasia and small numbers of connective tissue with larger lobules when compared with the untreated group. In silico tubulin-binding interactions revealed that C6 binding to tubulin was like that of colchicine, and also has higher affinity to tubulin than colchicine.
The synthesized chalcone demonstrated significant antitumor activities in MNU-induced mammary tumors in rats postulated via inhibition of tubulin polymerization.
Detection of genes conferring resistance on multi antibiotic resistance bacteria isolated from ready to eat foods sold in the Nigerian defence academy, Kaduna, Nigeria
Authors: Ayuba-Buhari Sherifat Bukola , Ozojiofor Ugochukwu 
Published: March 2024

Food has always been the means by which disease-causing organisms are transmitted to man. This study sought to isolate multi-antibiotic resistant bacteria from ready to eat food (RTE) sold within Nigerian Defence Academy. Eight (8) food samples were collected from five (5) vendors and spread plate technique was adopted for bacteria isolation from the food samples. Twenty-five (25) bacteria isolates were obtained from the food samples and subjected to antibiotic sensitivity assay using Kirby Bauer disc diffusion method. Eight (8) of the isolates exhibited various degrees of resistance to the tested antibiotics. All the isolated bacteria in this study were susceptible to the effect of Quinolones antibiotics and were resistant to cefuroxime, cefotaxime and Ampiclox. Six (6) of the isolates that showed multi-antibiotic resistance were characterized by 16SrRNA gene sequencing as Bacillus cereus strains (0083 and HYM76), Staphylococcus aureus strain MRSA252, Lactobacillus murinus strain AMB_10 and Listeria Spp. Polymerase chain reaction (PCR) and agarose gel electrophoresis detection of four (4) antibiotics resistance genes – Aminoglycoside adenylyltransferase (AADA1), Acridine (ACRA), Chloramphenicol Resistance (CMLA) and Erythromycin (ERM(C)) – produced the following results: AADA1 genes were amplified in Staphylococcus aureus and Bacillus cereus; ACRA gene was detected in all the selected isolates; CMLA gene was detected in Staphylococcus aureus, Lactobacillus murinus and Bacillus cereus while ERM(C) gene was present in Staphylococcus aureus.
Qualitative and quantitative phytochemical profiling of ethnomedicinal folklore plant- Globimetula oreophila
Authors: DAUDA GARBA , Ali Bila Hassan , Muhammed Sani Yahaya , Muhammad Magaji Garba , Ismail Abdullahi Musa , Muhammad Musa Aliyu , Hassan Halimatu Sadiya 
Published: March 2024

Globimetula oreophila is a hemiparasitic plant commonly called mistletoe, found growing on several dicotyledonous trees using them as a host for its root-like structure called haustoria. Globimetula oreophila has been used to cure a variety of ailments, including diarrhea, stomachache, headache, and fever. As a treatment for these ailments, the leaves and stem are boiled and the resulting decoction is drunk. The phytochemical compositions have not yet been scientifically confirmed despite their potential for medicinal use. The present study is aimed at investigating the leaves of G. oreophila fraction for phytochemicals, by qualitative and quantitative analysis. It was observed that from the qualitative screening, different fractions confirmed the presence of carbohydrates, saponins, cardiac glycoside, tannins, flavonoids, steroid/triterpene, and alkaloids. Anthraquinones were not observed in any of the fraction of G. oreophila plant. Further, the study of the quantitative findings revealed that the butanol fraction had more secondary metabolites when compared with other fractions and the crude extract. Higher flavonoid content was found in the butanol fraction as compared to crude ethanol extract (CEE) while phenols were found to be higher in crude ethanol extract as compared to the butanol fraction. There were significant differences in the total phytochemical contents of each fraction. The results also show that the analyzed plant is a beneficial source of secondary metabolites and may have contributed to the therapeutic use of the plant in traditional medicine for the management of diseases.
Effect of some aspirin analogues on SW480 Colorectal cancer cell line: Tip of the iceberg
Authors: Bashir Asma’u Ismail , Garba Musa  , Perry Christopher J  , Nicholl Iain D  
Published: March 2024

Abstract
Colorectal cancer (CRC) is the third most common cancer and second leading cause of death with approximately 1.9 million cases and almost a million deaths worldwide in 2020. It is predicted that the global incidences of CRC will be over 3 million in 2040. Aspirin has been shown to have cytotoxic and immunomodulatory effects on CRC cell lines. However, due to side effects such as gastrointestinal bleeding in older patients, there has always a quest for safer and more effective analogues, leading to the synthesis of aspirin analogues. One of the primary regulators of the mitochondria-mediated pathway to apoptosis is the family known as BCL-2 proteins, which are broadly grouped into pro-apoptotic proteins such as BAX, BAK, BIK, BAD and anti-apoptotic proteins such as BCL-2 and BCL-XL.
Phase contrast images of the SW480 CRC cells treated with aspirin, meta-aspirin, para-aspirin, ortho-thioaspirin, meta-thioaspirin and para-thioaspirin at 0.5 mM for 24 h, 48 h and 72 h were taken at 100X magnification.
Western blot was used to detect BAX and BCL-2 proteins by treating CRC cells with aspirin and its analogues, and analysed by SDS-PAGE and immunoblotting. The blots were then probed with primary antibodies BCL-2 and BAX, after which the HRP bound protein-labelled antibody was visualised using ECL and exposed to CL-XPosure™ Film.
It was observed that the isomers of aspirin (O-ASP), meta-aspirin (M-ASP) and para-aspirin (P-ASP) significantly increased the density of BAX Ab. O-ASP, M-ASP, P-ASP and ortho-thioaspirin (O-TASP) significantly reduced the density of BCL-2 Ab, thus proposing that the anti-apoptotic effect of this cell line is reversed/reduced by these aspirin analogues.
The results of this study suggest that M-ASP and P-ASP have its antiproliferative effect on the SW480 CRC cell line via driving the pro-apoptotic effect of BAX protein and decreasing the expression of anti-apoptotic of BCL-2 protein, thus, encouraging apoptosis in this CRC cell line.
Molecular characterization of antimicrobial resistance and virulence factors in coagulase – negative staphylococci nasal isolates among adult patients in a tertiary hospital in North-Western Nigeria
Authors: Atolagbe Cecilia Towobola , Tytler Babajide Akinyele , Jimoh Olanrewaju , Olayinka Adebola Tolulope , Oyegoke Paul Ifeleke , Olayinka Busayo Olalekan 
Published: March 2024

Coagulase-negative staphylococci are harmless microorganisms that can become pathogenic when the host resistance is impaired. Their ability to exhibit multidrug-resistance and form biofilm limit treatment options and contributes to the health and financial burden on health care systems worldwide. This study aimed to provide data on the acquisition and expression of genetic elements associated with resistance and virulence in the organisms from nasal colonization of adults admitted to a University Teaching Hospital in Nigeria. One hundred and twenty-three presumptive staphylococci isolates were obtained from the medical microbiology laboratory of Ahmadu Bello University Teaching Hospital (ABUTH), Zaria. The isolates were characterized, and the antibiotics susceptibility pattern assessed. Biofilm formation was evaluated by the micro-titre plate method, and polymerase chain reaction was used to detect resistance genes (mecA and ermB), virulence gene (psm-mec) and adhesin genes, (icaAB, icaC and icaD) in the isolates.
Out of the 60 coagulase-negative staphylococci isolates, 50 (83.3%) were strong biofilm formers, 5 (8.3%) were moderate biofilm formers and 5 (8.3%) were weak biofilm formers. For the 14 isolates that were characterized by PCR, mecA and ermB resistance genes were detected in 78% and 71% of the isolates respectively. Twenty-one percent had psm-mec virulence gene while biofilm adhesin genes, icaAB and icaD were detected in 36% and 57% respectively, icaC gene was not detected.
This study confirmed formation of biofilm, carriage of resistance and virulence genes which have been shown to play a role in pathogenesis. This study shows the necessity of the periodical monitoring of the drug resistance pattern and virulence factors of coagulase-negative staphylococci.
Telaah Terhadap Banyaknya Permohonan Praperadilan Yang Gagal
Authors: Malaka Zuman 
Published: March 2024

Abstract
The Pretrial Institution is the authority possessed by the District Court to examine and decide whether or not the arrest and/or detention of a suspect is legal, terminate the investigation or prosecution, as well as request for compensation or rehabilitation by the suspect. This research uses a type of library research, namely research related to reading, recording and managing materials used in activities related to research. The data collection technique uses library research. The results of the study show that many pretrial application practices fail due to failure to fulfill formal and material requirements as well as inconsistencies between the arguments submitted and a lack of sufficient evidence to justify the pretrial application.
Keywords: Application, Pretrial

Abstrak
Lembaga Praperadilan adalah kewenangan yang dimiliki oleh Pengadilan Negeri untuk memeriksa dan memutus sah atau tidaknya penangkapan dan atau penahanan tersangka, penghentian penyidikan atau penuntutan, serta permohonan ganti rugi atau rehabilitasi oleh tersangka. Penelitian ini menggunakan jenis penelitian kepustakaan (library research), yakni penelitian yang berkenaan dengan membaca, mencatat dan mengelola bahan-bahan yang digunakan dalam kegiatan yang berkaitan dengan penelitian. Teknik pengumpulan datanya menggunakan studi kepustakaan. Hasil kajian menunjukkan bahwa banyaknya praktik permohonan praperadilan yang gagal dikarenakan tidak memenuhi syarat formil dan materiil serta ketidaksesuaian antara argumen yang diajukan serta kurangnya bukti yang cukup untuk membenarkan permohonan praperadilan tersebut.
Kata Kunci: Permohonan, Praperadilan
Climate changes impact on the distribution of vegetation in Wasit and Nineveh regions of Iraq
Authors: BAKR DHER I. , JASIM Al-KHALIDI  , HAMID BASHAR TALIB 
Published: March 2024

Climate changes have a direct or indirect impact on many vital systems, including human and animal, as well as vegetation. The monthly precipitation and temperature for the period (1981-2021) and vegetation images (NDVI) for the period (2000-2022) from the satellite (NASA) for the regions of Ninevah and Wasit of Iraq were used to find out their variations over the space and time. It was found that the temperature was increasing with time, but the precipitation was in a state of turbulent increase in the two study areas. The distribution of vegetation was also in a state of change with time as well as within a region. The vegetation area increased with increase in precipitation which was greater in the Ninevah region than in the Wasit region. When there was a lack of precipitation, the vegetation cover area decreased in the two study areas. The increase in temperature also resulted in a decrease in the density and area of vegetation. It was found that the change in the amount of precipitation was more influential than the change in temperature on the vegetative distribution.
Developing weather-based biomass prediction equation to assess the field pea yield under future climatic scenario
Authors: MUKHERJEE AISHI , SAON BANERJEE  , SARATHI SAHA  , NATH RAJIB , MANISH KUMAR NASKAR  , ASIS MUKHERJEE  
Published: March 2024

The present research focuses on the variation of field pea production under different prevailing weather parameters, aiming to develop a reliable forecasting model. For that a field experiment was conducted in New Alluvial Zone of West Bengal during 2018-19 and 2019-20 with three different varieties (VL42, Indrira Matar, Rachana) of this region. Biomass predicting equation based on maximum temperature, minimum temperature and solar radiation was developed to estimate field pea yield for 2040-2099 period under SSP 2-4.5 and SSP 5-8.5 scenarios. It reveals that solar radiation positively influences crop biomass, while high maximum and minimum temperatures have adverse effects on yield. The developed forecasting equation demonstrated its accuracy (nRMSE=17.37%) by aligning closely with historical data, showcasing its potential for reliable predictions. Furthermore, the study delves into future climate scenarios, showing that increasing temperatures are likely to impact field pea yield negatively. Both biomass and yield showed decreasing trend for the years from 2040 to 2099. SSP 5-8.5 scenario, which is more pessimistic one, foresees a substantial reduction in crop productivity. This weather parameter-based biomass prediction equation can be effectively utilized as a method to assess the impact of climate change on agriculture.
Keywords: Field pea, weather parameters, crop yield prediction, New Alluvial Zone, nRMSE
Kriteria Keputusan Peningkatan Produktifitas Konfigurasi Ruang Di Rusunawa Dabag Kab. Sleman DI Yogyakarta
Authors: Fazri Ilham , Naufal Muhammad Rafif , Alrizqi Muhammad Rafli 
Published: March 2024

Terkait produktivitas konfigurasi ruang, kompleks rusunawa sering dianggap kurang terawat, sehingga diperlukan konfigurasi ruang yang dapat meningkatkan produktivitasnya dan biaya operasional bangunan dapat terpenuhi. Masalah yang sering terjadi di banyak kompleks rusunawa adalah kriteria keputusan yang harus dibuat untuk meningkatkan produktivitas konfigurasi ruang, terutama di kompleks apartemen Dabag Yogyakarta. Penelitian ini menggunakan preferensi dan persepsi penghuni untuk minat tinggal di kompleks apartemen melalui uji validitas di kompleks apartemen Dabag dengan kuesioner dan pengubahan konfigurasi ruang yang ada dengan konfigurasi baru yang mempertimbangkan kondisi lapangan sebagai evaluasi dari variabel pendukung seperti kedekatan kompleks rusunawa dan fasilitas, serta biaya investasi yang harus dikeluarkan. Hasilnya, kompleks apartemen Dabag memiliki kriteria dalam pembuatan keputusan untuk meningkatkan produktivitas konfigurasi ruang yang lebih tinggi, yaitu dengan menambahkan lapangan olahraga, taman bermain, taman, ruang serbaguna. Hasil peneliian dapat menjadi acuan dalam peningkatan produktivitas konfigurasi ruang, kompleks rusunawa yang dibutuhkan.
Identifikasi Faktor-Faktor Yang Mempengaruhi Prestasi Mahasiswa Teknik Informatika dan Bisnis Digital Menggunakan Regresi Logistik Binary
Authors: Addini Puteri Fajar , Saputra Dakhi Kevin Raih , Cania Tarigan Putri 
Published: March 2024

Dalam proses pendidikan tinggi Indeks Prestasi Kumulatif (IPK) merupakan indikator keberhasilan mahasiswa. Tujuan dari penelitian ini adalah untuk mengetahui model regresi logistik biner dan mengidentifikasi faktor-faktor yang dapat memengaruhi IPK mahasiswa program studi teknik informatika dan bisnis digital. Populasi dalam penelitian ini adalah mahasiswa aktif program studi teknik informatika dan bisnis digital T.A 2020/2021 yang berjumlah 50 mahasiswa dan T.A 2021/2022 yang berjumlah 50 mahasiswa total keseluruhan populasi adalah sebanyak 120 mahasiswa, dengan jumlah responden yang mengembalikan kuesioner penelitian sebanyak 100 responden. Indeks Prestasi Kumulatif (IPK) sebagai variabel respon (Y) dan jenis kelamin (), usia (),tempat tinggal (), lama belajar (). program studi, jenis kelamin dan usia berpeluang memiliki pengaruh terhadap Indeks Prestasi Kumulatif (IPK) mahasiswa teknik informatika dan bisnis digital di STMIK Pelita Nusantara.