bluuebunny/crossref_metadata_2025_split huggingface dataset:
Metals levels and human health risk assessment in eight commercial fish species collected from a market, Wuhan, China
Authors: Yin Jiaojiao , Cheng Liangyu , Jiang Xiaoming , Wang Li , Gao Pan , Zhong Wu , Zhang Xuezhen 
Published: April 2024

IntroductionHeavy metals are ubiquitous environmental pollutants, and fish could be contaminated by these metals, potentially posing a threat to human health through the food chain. Understanding the accumulation of these metals in fish tissues is crucial for assessing the safety of consuming fish products.MethodsIn this study, the distribution of nickel (Ni), copper (Cu), zinc (Zn), cadmium (Cd), and lead (Pb) in tissues of eight fish species (Ctenopharyngodon idellus, Megalobrama amblycephala, Hypophthalmichthys molitrix, Hypophthalmichthys nobilis, Carassius auratus, Cyprinus carpio, Culter alburnus, and Lateolabrax japonicas) collected from the Baishazhou market with different trophic levels and habitat preference was investigated using inductively coupled plasma mass spectrometry (ICP-MS). The metal accumulation capacity of different fish tissues and species was assessed, and the metal pollution index (MPI) was calculated to evaluate the extent of metal accumulation ability in each species. Additionally, the health risk assessment was conducted to evaluate the potential threat to human health posed by consuming these fish species.ResultsThe levels of metals exhibited variation among different fish tissues and species, showing an order of Zn &gt; Cu &gt; Ni &gt; Pb &gt; Cd. In terms of tissues, fish head demonstrated a greater capacity for metal accumulation compared to the muscles. Regarding fish species, the extent of accumulation ability varied depending on the specific metal, exhibiting the following order according to MPI: H. molitrix (0.568) &gt; C. auratus (0.508) &gt; M. amblycephala (0.469) &gt; C. idellus (0.336) &gt; C. alburnus (0.315) &gt; C. carpio (0.274) &gt; L. japonicus (0.263) &gt; H. nobilis (0.206). Furthermore, in accordance with the results of health risk assessment, there was no potential health risk associated with the consumption of these fish species, as all target hazard quotient (THQ) values (ranger from not detected to 0.192) were below 1, and the maximum hazard index (HI) value was observed in C. carpio (0.519 for adults, 0.622 for children).ConclusionThe findings of this study demonstrate the distribution of heavy metals in fish tissues and indicate there were no potential health risk associated with consuming these fish bought from the Baishazhou market.
Electronic medical record system for school dental hygienists: a preventive focus
Authors: Burnashova T. I. , Skripkina G. I. 
Published: April 2024

Relevance. Clinical documentation remains a cornerstone of medical practice. Over the last decade, there has been a notable evolution in the standards for medical documentation and the speed of processing due to advancements in healthcare information technology, including electronic medical record systems. Despite the Ministry of Health of Russia endorsing specific documentation procedures for healthcare organizations, pediatric preventive care dental services have not yet been provided with an appropriate electronic documentation format.Materials and methods. The development of the electronic medical record system for dental hygienists employed Qt Creator software (http://www.qt.io/), using the C++ programming language framework (http://www.isocpp.org/). The system's efficacy was evaluated through testing across the Omsk region over the period 2020-2021.Results. The project resulted in the successful creation of an electronic medical record system designed for dental hygienists.Conclusion. The new electronic medical record system is set to greatly improve the effectiveness of primary preventive care for dental specialists.
How to Measure the Impact Generated by the Gender Equality Plan?
Authors: Brescianini Aanna , Bannò Mariasole , Federici Camilla 
Published: April 2024

Gender Equality Plans (GEPs) are the primary policy tool to advance gender equality in research and innovation in Europe. The European Commission has mandated an institutional requirement for all public and research performing organisations applying for Horizon Europe 2021-2027 grants. These entities must develop GEPs addressing organisational culture, work-life balance, gender balance in leadership, recruitment and career progression, gender mainstreaming in research and teaching, and measures against gender-based violence. The Commission has outlined four mandatory elements for GEPs: they must be public documents, allocate resources for implementation, be based on sex/gender-disaggregated data collection and monitoring, and include training and capacity building. This new requirement is expected to stimulate significant activity at institutional and state levels across EU countries. From the research presented here, we expect an ongoing self-assessment of the progress of the actions implementation to reduce gender inequality and valuable suggestions for the future GEP UniBs 2025-2027 design and planning.
Drug-Induced QT Prolongation
Authors: Королева А.А. , Журавков Ю.Л. 
Published: April 2024

Внезапная сердечная смерть является важной причиной смертности в развитых странах, большинство из этих случаев являются следствием желудочковых аритмий. Эти аритмии в некоторых ситуациях обусловлены удлинением интервала QT. Синдром удлинения интервала QT может быть врожденным и приобретенным. Ряд лекарственных препаратов могут увеличить риск удлинения интервала QT. Принимая во внимание тяжесть такого события, клиницистам важно знать риски, связанные с применением этих препаратов у определенных пациентов. В этой статье описываются препараты, удлиняющие интервал QT, факторы риска и взаимодействия лекарств, которые могут привести к удлинению интервала QT.
Sudden cardiac death is an important cause of mortality in developed countries, most of them being the consequence of ventricular arrhythmias. These arrhythmias, in some cases, owe to QT interval prolongation. Long QT syndromes can be either acquired or congenital. Several medicines can increase the risk of a long QT interval. Taking into account the severity that the occurrence of such an event may have, it is important for clinicians to know risks of these drugs in certain patients. This article describes the drug that prolongs the QT interval, risk factors and drug interactions that can lead to QT prolongation.
Periprosthetic Infection: Approaches to Antibacterial Therapy
Authors: Талако Т.Е. , Абельская И.С. , Слободин Ю.В. , Галицкая С.С. , Качанко Е.Ф. , Козаченко М.Г. , Конончук С.Н. , Дудинский А.К. 
Published: April 2024

Перипротезная инфекция суставов (ППИ) является одним из наиболее разрушительных и дорогостоящих осложнений после тотального эндопротезирования суставов (ТЭС). Диагностика и лечение ППИ является сложной задачей для врачей-ортопедов. Не существует «золотого стандарта» диагностики ППИ. Бывает достаточно сложно разобраться между септическими и асептическими нарушениями. Кроме того, некоторые из самых больших трудностей и противоречий связаны с выбором оптимального метода лечения инфицированного сустава. До сих пор ведутся серьезные дебаты относительно идеальной стратегии лечения ППИ, что привело к значительным международным различиям как в хирургическом, так и в нехирургическом лечении ППИ. Инфекция, связанная с артропластикой, или перипротезная инфекция сустава, является редким заболеванием и клинически отличается от инфекции нативной кости или сустава. ППИ предполагает взаимодействие между микроорганизмами, с одной стороны, и имплантатом и иммунной системой хозяина, с другой. Небольшое количество микроорганизмов может вызвать ППИ. Бактерии (и в редких случаях грибы) прикрепляются к поверхностям протезированного сустава и образуют биопленки. Биопленки, как правило, устойчивы ко многим противомикробным агентам и иммунной системе хозяина. Возбудителями может быть микробиота кожи, инокулированная при установке протеза.
Periprosthetic joint infection (PJI) is one of the most devastating and costly complications following total joint arthroplasty (TJA). Diagnosis and treatment of PJI is a challenging task for orthopedic physicians. There is no gold standard for diagnosing PJI. It can be quite difficult to understand between septic and aseptic disorders. Additionally, some of the greatest difficulties and controversies involve choosing the optimal treatment method for an infected joint. There is still considerable debate regarding the ideal treatment strategy for PJI, which has led to significant international variation in both surgical and non-surgical treatment of PJI. Arthroplasty-associated infection, or periprosthetic joint infection, is a rare condition and clinically distinct from infection of the native bone or joint. PPI involves an interaction between microorganisms, on the one hand, and the implant and the host’s immune system, on the other. A small number of microorganisms can cause PJI. Bacteria (and in rare cases fungi) attach to the surfaces of the prosthetic joint and form biofilms. Biofilms are generally resistant to many antimicrobial agents and the host immune system. Pathogens may be skin microbiota inoculated during installation of the prosthesis.
Further Restrictions on Use to Avoid Topiramate Exposure in Pregnancy
Authors: Кучко А.М. , Ефремова И.Н. , Федосеева И.И. 
Published: April 2024

Существуют свидетельства о связи между применением топираматсодержащих лекарственных препаратов беременными женщинами и развитием серьезных нарушений внутриутробного развития плода (например, черепно-лицевыми дефектами, такими как заячья губа / волчья пасть, гипоспадией и аномалиями развития различных систем организма). В настоящее время также установлено, что лекарственные препараты, содержащие топирамат, при применении беременной женщиной могут повышать риск нарушений нейропсихического развития ребенка. В рамках функционирования системы фармаконадзора с целью минимизации риска неблагоприятного воздействия на плод в Республике Беларусь планируется внедрение дополнительной меры минимизации рисков – программы по предотвращению беременности для топираматсодержащих лекарственных препаратов.
Topiramate-containing medicines is known to be associated with an increased risk of congenital fetal malformations (particularly cleft lip/palate, hypospadias, and anomalies involving various systems) if used during pregnancy. It has been additionally established that topiramate-contained medicines used by woman during pregnancy may increase the risk of neurodevelopmental disorders in children. As part of the pharmacovigilance system functioning in order to minimize adverse effects on an unborn child, in the Republic of Belarus it is planned implementation of Pregnancy Prevention Program for topiramate-containing medicines.
"Сhess Studies" of Antimicrobial Therapy
Authors: Дедюшко Г.В. 
Published: April 2024

В статье в научно-популярном стиле рассмотрена тема рациональной антимикробной терапии и представлены основные актуальные ее аспекты, ассоциированные с игрой в шахматы.
Updating the topic "Of rational antimicrobial therapy" in a popular scientific and literary style and presents its main relevant aspects associated with the game of chess.
Peculiarities of the Use of Medicines in Patients with Impaired Hepatic Function
Authors: Кожанова И.Н. , Чак Т.А. , Мацкевич С.А. , Романова И.С. 
Published: April 2024

Фармакокинетика многих лекарственных средств существенно изменяется у пациентов с заболеваниями печени и почек, что влечет за собой и изменение фармакодинамики с возможным увеличением вероятности нежелательных лекарственных реакций. Правильный подбор лекарственных средств и их дозирование для этих категорий пациентов является сложной задачей в клинической практике врача любой специальности. Большинство инструкций по медицинскому применению лекарственных препаратов предлагают коррекцию дозы при заболеваниях печени, основанную на оценке степени нарушения ее функции по шкале Чайлда – Пью. В статье рассмотрены системы оценки печеночной функции, такие как MELD (The Model for End-Stage Liver Disease, 2016), критерии Национального института рака для определения стадии повреждения печени, шкала категорий тяжести Международной экспертной рабочей группы по лекарственно-индуцированным поражениям печени, и другие. Наиболее безопасными с точки зрения изменения фармакокинетики у пациентов с нарушением функции печени без сопутствующей почечной недостаточности являются лекарственные средства, выделяющиеся более чем на 90% в неизмененном виде с мочой.
The pharmacokinetics of many drugs changes significantly in patients with liver and kidney diseases. This entails changes in pharmacodynamics with a possible increase in the likelihood of undesirable drug reactions. The correct selection of drugs and their dosing for these categories of patients is a difficult task in the clinical practice of a doctor of any specialty. Most instructions for the medical use of medications offer dose adjustment for liver diseases based on the assessment of the degree of impairment of its function on the Child-Pugh scale. The article also discusses systems for assessing liver function, such as MELD (The Model for End-Stage Liver Disease, 2016), the Criteria of the National Cancer Institute for determining the stage of liver damage, the scale of severity categories of the International Expert Working Group on Drug-Induced Liver Lesions, and others. The safest drugs for patients with impaired liver function alone are drugs that are excreted more than 90% unchanged in urine.
The Effect of Using (Microsoft Teams) to Teach the Physical and Health Education Teaching Methods Course on the Achievement of Al-Hussein Bin Talal University students and their Acquisition of Reflective Thinking Skills
Authors: Alwama Hussein Ali Mohammed , Albdour Amin Dakhalalah Abdallah 
Published: April 2024

Objectives: This study aimed to identify the effect of using the distance learning platform (Microsoft Times) to teach the physical and health education methods course on each of the study variables, namely: the achievement of Al-Hussein Bin Talal University students, and the students' acquisition of reflective thinking skills.
Methods: The study used the quasi-experimental approach by selecting two divisions from the Physical and Health Education Teaching Methods course and distributing them randomly into two experimental and control groups. The study used an achievement test and a reflective thinking test.
Result: In light of the statistical analysis, the results showed a statistically significant effect in the dimensional measurement of using the distance learning platform (Microsoft Teams) to teach the Physical and Health Education Teaching Methods course on the achievement and acquisition of reflective thinking skills by the students of Al-Hussein Bin Talal University, in favor of the students of the experimental group.
Conclusions: In light of the results of the study, a number of recommendations were reached, the most important of which are: using the distance learning platform in university teaching and in other study courses.
Demonstration of a violet-distributed feedback laser with fairly small temperature dependence in current-light characteristics
Authors: Fukamachi Toshihiko , Nishinaka Junichi , Naniwae Koichi , Usuda Shuichi , Fukai Haruki , Sugitani Akihiko , Uemukai Masahiro , Tanikawa Tomoyuki , Katayama Ryuji 
Published: April 2024

Abstract
We have developed a GaN-based distributed feedback laser diode (DFB-LD) with the detuning of +5 nm to obtain a smaller temperature dependence of the threshold current. We found that the current-light characteristics almost overlapped up to 300 mW between 25 °C and 80 °C. The estimated characteristic temperature is about 2550 K. These indicate that our DFB-LD is promising for applications that require small temperature dependence in the output power and oscillation wavelength at constant operation current without precise temperature control.
An initial basic feasible transportation solution based on the north-west corner rule programming in c
Authors: M RAMAKRISHNA , G Ashok 
Published: April 2024

Transportation is one of the most important problems in operations research because it is involved in our daily activities and is primarily concerned with logistics. It is a very important class of linear programming model that deals with the condition of transporting commodities or resources from sources to destinations. The problem's primary goal is to save transportation time and steps by using minimal transformation costs. The solution to this problem is classified into two types: the Initial Basic Feasible Solution (IBFS) and the Optimal Solution (OS). The purpose of this research is to develop a programme that employs the North West Corner Rule to determine the Initial Basic Feasible solution to the transportation problem (NWCR). This programme was written in C# and can handle both balanced and unbalanced situations. Furthermore, the North West Corner Rule has a broader application than other methods for solving transportation problems. Finally, the proposed programme is more useful for decision makers who deal with unbalanced supply and demand quantities on a regular basis.
Influence of School Based Factors on Implementation of Curriculum in Primary Schools in Banadir Region Mogadishu Somalia
Authors: Mohamud Mahad Salad 
Published: April 2024

This study investigates the school-based factors influencing curriculum implementation in primary schools within the Banadir region of Mogadishu, Somalia. Guided by three research objectives, the study examines the influence of time allocation, the impact of teacher training, and the availability of teaching and learning materials on curriculum implementation. The literature review centres on appropriate objectives, A descriptive survey design is employed, with a target population of 48 primary schools, 1520 pupils, 404 teachers, and 48 head teachers in the Banadir region. Sampling methods include simple random sampling for participating schools and teachers and stratified random sampling for pupils. Data is collected through questionnaires, and analysis is conducted using SPSS version 20, Quantitative data was analysed using descriptive statistics; frequencies, and percentages. The findings reveal that time allocation significantly influences curriculum implementation, with pupils and teachers indicating insufficient time despite head teachers' contrary views. The study establishes that the level of teacher training also plays a crucial role in curriculum implementation. Furthermore, the availability of teaching and learning materials is identified as a key factor influencing curriculum implementation. Recommendations include additional lesson allocations to enhance curriculum coverage and ensuring the provision of adequate teaching and learning materials
Computed tomography-based radiomics to predict early recurrence of hepatocellular carcinoma post-hepatectomy in patients background on cirrhosis
Authors: Qian Gui-Xiang , Xu Zi-Ling , Li Yong-Hai , Lu Jian-Lin , Bu Xiang-Yi , Wei Ming-Tong , Jia Wei-Dong 
Published: April 2024

BACKGROUND
The prognosis for hepatocellular carcinoma (HCC) in the presence of cirrhosis is unfavourable, primarily attributable to the high incidence of recurrence.
AIM
To develop a machine learning model for predicting early recurrence (ER) of post-hepatectomy HCC in patients with cirrhosis and to stratify patients’ overall survival (OS) based on the predicted risk of recurrence.
METHODS
In this retrospective study, 214 HCC patients with cirrhosis who underwent curative hepatectomy were examined. Radiomics feature selection was conducted using the least absolute shrinkage and selection operator and recursive feature elimination methods. Clinical-radiologic features were selected through univariate and multivariate logistic regression analyses. Five machine learning methods were used for model comparison, aiming to identify the optimal model. The model’s performance was evaluated using the receiver operating characteristic curve [area under the curve (AUC)], calibration, and decision curve analysis. Additionally, the Kaplan-Meier (K-M) curve was used to evaluate the stratification effect of the model on patient OS.
RESULTS
Within this study, the most effective predictive performance for ER of post-hepatectomy HCC in the background of cirrhosis was demonstrated by a model that integrated radiomics features and clinical-radiologic features. In the training cohort, this model attained an AUC of 0.844, while in the validation cohort, it achieved a value of 0.790. The K-M curves illustrated that the combined model not only facilitated risk stratification but also exhibited significant discriminatory ability concerning patients’ OS.
CONCLUSION
The combined model, integrating both radiomics and clinical-radiologic characteristics, exhibited excellent performance in HCC with cirrhosis. The K-M curves assessing OS revealed statistically significant differences.
THE The Effect Of Ring Frame Thread Number And Winding Machine Counter On The Weight Of 69G Lot Cones On Winding Machine Number 8
Authors: Pravitasari Filly , Kusumadewi Afriani , Nurherawaty Feny , Sulistio Rino 
Published: April 2024

Abstract: A good and appropriate product quality control system can maintain product quality in accordance with the standards set by the company. Fabrics produced at PT X still has problems, namely the existence of product defects that exceed the maximum tolerance limit for defective products that have been set by the company, which is 2%. Types of fabric defects that often occur include color not ok (WTO), spot defects, crease marks and dirty color, so it is necessary to do an analysis for product quality control in each process using statistical quality control methods. ). Statistical quality control can detect the existence of special causes in variations or process errors through analysis of data from the past and the future by finding the cause of damage or product defects through existing data. Based on the results of the p control chart (p-chart) it was found that the quality of 100% viscose rayon fabric was outside the control limit, it was shown that there were still points that were outside the control limit and these points fluctuated very high and irregularly. This is an indication that the process is in an uncontrolled state or is still experiencing deviations. Furthermore, the results of the causal diagram analysis can identify the factors that cause defects in the production process, which are derived from factors of workers, production machines, work methods, and dyestuff/material. The data from the statistical quality control results can be quickly corrected so that the same mistakes do not happen again.
Keywords : Quality Control, Fabric Defects, fishbone diagram