bluuebunny/crossref_metadata_2025_split huggingface dataset:
Expectation violations signal goals in novel human communication
Authors: Buidze Tatia , Sommer Tobias , Zhao Ke , Fu Xiaolan , Gläscher Jan 
Published: February 2025

Abstract
Communication, often grounded in shared expectations, faces challenges when a Sender and Receiver lack a common linguistic background. Our study explores how people instinctively turn to the fundamental principles of the physical world to overcome such barriers. Specifically, through an experimental game in which Senders convey messages via trajectories, we investigate how they develop novel strategies without relying on common linguistic cues. We build a computational model based on the principle of expectancy violations and a set of common universal priors derived from movement kinetics. The model replicates participant-designed messages with high accuracy and shows how its core variable—surprise—predicts the Receiver’s physiological and neuronal responses in brain areas processing expectation violations. This work highlights the adaptability of human communication, showing how surprise can be a powerful tool in forming new communicative strategies without relying on common language.
Interpolating numerically exact many-body wave functions for accelerated molecular dynamics
Authors: Rath Yannic , Booth George H. 
Published: February 2025

Abstract
While there have been many developments in computational probes of both strongly-correlated molecular systems and machine-learning accelerated molecular dynamics, there remains a significant gap in capabilities in simulating accurate non-local electronic structure over timescales on which atoms move. We develop an approach to bridge these fields with a practical interpolation scheme for the correlated many-electron state through the space of atomic configurations, whilst avoiding the exponential complexity of these underlying electronic states. With a small number of accurate correlated wave functions as a training set, we demonstrate provable convergence to near-exact potential energy surfaces for subsequent dynamics with propagation of a valid many-body wave function and inference of its variational energy whilst retaining a mean-field computational scaling. This represents a profoundly different paradigm to the direct interpolation of potential energy surfaces in established machine-learning approaches. We combine this with modern electronic structure approaches to systematically resolve molecular dynamics trajectories and converge thermodynamic quantities with a high-throughput of several million interpolated wave functions with explicit validation of their accuracy from only a few numerically exact quantum chemical calculations. We also highlight the comparison to traditional machine-learned potentials or dynamics on mean-field surfaces.
Microbiome modulation of implant-related infection by a novel miniaturized pulsed electromagnetic field device
Authors: Souza João Gabriel S. , Azevedo Fabio , Borges Maria Helena Rossy , Costa Raphael Cavalcante , Shiba Takahiko , Barak Shlomo , Mayer Yaniv , Figueiredo Luciene Cristina de , Feres Magda , Barão Valentim A. R. , Shibli Jamil A. 
Published: February 2025

Abstract
Dental implant-related infections, which lack effective therapeutic strategies, are considered the primary cause for treatment failure. Pulsed electromagnetic field (PEMF) technology has been introduced as a safe and effective modality for enhancing biological responses. However, the PEMF effect on modulating microbial diversity has not been explored. Thus, we tested a miniaturized PEMF biomedical device as a healing component for dental implants. PEMF activation did not alter the chemical composition, surface roughness, wettability, and electrochemical performance. PEMF effectively controlled chronic in vitro polymicrobial microbial accumulation. The in vivo study where devices were inserted in the patients’ oral cavities and 16S RNA sequencing analysis evidenced a fivefold or more reduction in 23 bacterial species for PEMF group and the absence of some species for this group, including pathogens associated with implant-related infections. PEMF altered bacterial interactions and promoted specific bacterial pathways. PEMF has emerged as an effective strategy for controlling implant-related infections.
Glacial isostatic adjustment reveals Mars’s interior viscosity structure
Authors: Broquet A. , Plesa A.-C. , Klemann V. , Root B. C. , Genova A. , Wieczorek M. A. , Knapmeyer M. , Andrews-Hanna J. C. , Breuer D. 
Published: February 2025

Abstract
Investigating glacial isostatic adjustment has been the standard method to decipher Earth’s interior viscosity structure1,2, but such an approach has been rarely applied to other planets because of a lack of observational data3,4. The north polar cap of Mars is the only millions-of-years-old surface feature that can induce measurable surface deformation on this planet, thereby holding clues to its present-day internal viscosity structure5,6. Here we investigate the emplacement of this ice cap by combining thermal evolution models7, viscoelastic deformation calculations8 and radar observations6. We show that downward motion of the northern regions is ongoing and can be constrained by analyses of the time-variable gravity field9 and NASA’s InSight seismic moment rate10. Only models with present-day high viscosities (2–6 × 1022 Pa s for depths greater than 500 km), strong mantle depletion in radiogenic elements (more than 90%) and thick average crusts (thicker than 40 km) are consistent with the negligible flexure beneath the polar cap seen by radars. The northern lithosphere must deform at less than 0.13 mm per year and have a seismic efficiency less than 0.3 to satisfy gravity and seismic constraints, respectively. Our models show that the north polar cap formed over the last 1.7–12.0 Myr and that glacial isostatic adjustment can be further constrained by future gravity recovery missions to Mars11,12.
Interplay of geometrical and spin chiralities in 3D twisted magnetic ribbons
Authors: Farinha André M. A. , Yang See-Hun , Yoon Jiho , Pal Banabir , Parkin Stuart S. P. 
Published: February 2025

Abstract
Chirality is a ubiquitous and fundamental asymmetry in nature1,2. Recently, the interaction of chiral objects with spin currents has attracted enormous attention from both scientific and technological perspectives3–5. Of particular interest is the current-driven motion of chiral topological excitations such as chiral magnetic domain walls in chiral three-dimensional magnetic structures that could allow for high-density memory-storage devices. Here we use state-of-the-art multiphoton lithography6,7 to create three-dimensional chiral magnetic ribbons and perform current-induced motion of chiral domain walls. The ribbons are designed to have a clockwise or anticlockwise chiral twist with a variable magnitude. We find that domain walls can either pass through the ribbon or are impeded, depending on their chirality and configuration and the geometrical chiral twist of the ribbon. The interplay between the magnetic exchange energy and the geometrical twist generates a torsional field that favours chiral Bloch-type walls rather than the Néel-type wall favoured by the intrinsic magnetic properties of the magnetic ribbon itself. Furthermore, the interplay of spin chirality and chiral twist results in a non-reciprocal domain wall motion, namely, a domain wall filter or diode8–10. Our findings show how the interplay between geometrical and spin chiralities can lead to new functionalities that could allow for innovative chiral spintronics.
Humans in Africa’s wet tropical forests 150 thousand years ago
Authors: Ben Arous Eslem , Blinkhorn James A. , Elliott Sarah , Kiahtipes Christopher A. , N’zi Charles D. , Bateman Mark D. , Duval Mathieu , Roberts Patrick , Patalano Robert , Blackwood Alexander F. , Niang Khady , Kouamé Eugénie Affoua , Lebato Edith , Hallett Emily , Cerasoni Jacopo N. , Scott Erin , Ilgner Jana , Alonso Escarza Maria Jesús , Guédé Francois Yodé , Scerri Eleanor M. L. 
Published: February 2025

Abstract
Humans emerged across Africa shortly before 300 thousand years ago (ka)1–3. Although this pan-African evolutionary process implicates diverse environments in the human story, the role of tropical forests remains poorly understood. Here we report a clear association between late Middle Pleistocene material culture and a wet tropical forest in southern Côte d’Ivoire, a region of present-day rainforest. Twinned optically stimulated luminescence and electron spin resonance dating methods constrain the onset of human occupations at Bété I to around 150 ka, linking them with Homo sapiens. Plant wax biomarker, stable isotope, phytolith and pollen analyses of associated sediments all point to a wet forest environment. The results represent the oldest yet known clear association between humans and this habitat type. The secure attribution of stone tool assemblages with the wet forest environment demonstrates that Africa’s forests were not a major ecological barrier for H. sapiens as early as around 150 ka.
Enhancement of thermofluid characteristics via a triple-helical tube heat exchanger
Authors: Gomaa Abdalla , Gamal Yehia , Abdelmagied Mahmoud M. 
Published: February 2025

Abstract
An investigation of the thermal and hydraulic performance of a novel triple-helical tube heat exchanger, the THTHE, is presented. The novel design is a modified design of a DHTHE created by adding a third tube to a DHTHE tube. The third passage is expected to enhance the thermal performance of the DHTHE as a result of an increase in the temperature gradient between the hot and cold fluids. The effects of the coil radius, inner annulus spacing, water inlet temperature, direction of flow arrangement, and Dean number were explored. Five test samples with different coil radii of 150 mm, 125 mm, and 90 mm and different inner annulus spacings of 6.2 mm, 9 mm, and 12 mm were examined. The test samples were designed, fabricated, and tested to demonstrate the influence of design parameters on the thermal and hydraulic performance of the triple-helical tube heat exchanger. The experimental runs were conducted on the hot water side with the water inlet temperature T

h,i
ranging from 50:80 °C. Moreover, at Dean number 400 ≤ De

h
≤ 5500, corresponding to Reynolds number 2700 ≤ Re

h
≤ 31,000. Compared with the double-helical tube heat exchanger, the THTHE resulted in a higher Nusselt number by 146.1% and 109.3% for both the counterflow and parallel-flow arrangements, respectively. Furthermore, lowering the hot water source temperature from 80 to 50 °C results in a 60.6% increase in the Nusselt number of 60.6%, with no increase in the pumping power. Additionally, with a decreasing coil radius from 150 to 90 mm and inner annulus spacing from 12 to 6.2 mm, a significant increase in Nu occurs by 58.2% and 130.4%, respectively. A general correlation was presented for predicting Nu, f, and ε.
Quantitative autofluorescence is increased in clinically unaffected fellow eyes from patients with posterior uveitis
Authors: Finger Robert P. , Jungblut Julie , Just Marie D. , Terheyden Jan H. , Holz Frank G. , Liegl Raffael , Ach Thomas , Wintergerst Maximilian W. M. 
Published: February 2025

Abstract
The purpose of this prospective case-control study is to investigate differences in quantitative autofluorescence (qAF) in clinically affected and unaffected eyes of patients with inactive posterior uveitis compared to healthy, age-matched controls. Patients with posterior uveitis and healthy controls were imaged using fundus autofluorescence (488 nm excitation; Spectralis HRA + OCT; Heidelberg Engineering) to measure qAF values using the proprietary HEYEX software. Mean background qAF (excluding vessels and retinal lesions) across all segments (as previously defined by Delori et al.) and in the segment with the highest mean qAF value were compared between affected and unaffected eyes from patients with posterior uveitis, and healthy age-matched control eyes using the Kruskal-Wallis-test. A total of 83 eyes from 83 patients were included: 33 affected eyes (33 patients with uni-/bilateral posterior uveitis), 21 clinically unaffected eyes (21 patients with unilateral posterior uveitis), and 29 healthy, age-matched control eyes (29 patients). Mean qAF values were significantly higher (p-value < 0.0001) in both clinically affected (177.0 ± 83.8 qAF arbitrary units [qAF a.u.]) and unaffected (173.8 ± 56.4 qAF a.u.) eyes compared to healthy, age-matched controls (135.7 ± 41.8 qAF a.u.). Likewise, mean qAF in the segment with the highest mean qAF value was significantly higher (p-value: <0.01) in affected (243.2 ± 103.1 qAF a.u.) and unaffected eyes (227.1 ± 63.4 qAF a.u.) in comparison to controls (168.9 ± 48.5 qAF a.u.). In conclusion, both clinically affected and unaffected eyes from patients with posterior uveitis demonstrated increased fundus autofluorescence. The results of our study could indicate subclinical inflammation in currently inactive and (yet) unaffected eyes of posterior uveitis patients. This could be caused by accumulation of fluorophores or an increased metabolic activity generated by low-grade inflammation. As these changes may precede future inflammation in yet unaffected eyes, additional longitudinal studies including analysis of eyes with active disease are warranted.
DeepCristae, a CNN for the restoration of mitochondria cristae in live microscopy images
Authors: Papereux Salomé , Leconte Ludovic , Valades-Cruz Cesar Augusto , Liu Tianyan , Dumont Julien , Chen Zhixing , Salamero Jean , Kervrann Charles , Badoual Anaïs 
Published: February 2025

Abstract
Mitochondria play an essential role in the life cycle of eukaryotic cells. However, we still don’t know how their ultrastructure, like the cristae of the inner membrane, dynamically evolves to regulate these fundamental functions, in response to external conditions or during interaction with other cell components. Although high-resolution fluorescent microscopy coupled with recently developed innovative probes can reveal this structural organization, their long-term, fast and live 3D imaging remains challenging. To address this problem, we have developed a CNN, called DeepCristae, to restore mitochondria cristae in low spatial resolution microscopy images. Our network is trained from 2D STED images using a novel loss specifically designed for cristae restoration. To efficiently increase the size of the training set, we also developed a random image patch sampling centered on mitochondrial areas. To evaluate DeepCristae, quantitative assessments are carried out using metrics we derived by focusing on the mitochondria and cristae pixels rather than on the whole image as usual. Depending on the conditions of use indicated, DeepCristae works well on broad microscopy modalities (Stimulated Emission Depletion (STED), Live-SR, AiryScan and LLSM). It is ultimately applied in the context of mitochondrial network dynamics during interaction with endo/lysosome membranes.
Bioengineered 3D microvessels and complementary animal models reveal mechanisms of Trypanosoma congolense sequestration
Authors: Porqueddu Teresa , Zorrinho-Almeida Maria , De Niz Mariana , Casas-Sánchez Aitor , Introini Viola , Sanz Sender Silvia , Carrasqueira Diana , Figueiredo Luísa M. , Bernabeu Maria , Silva Pereira Sara 
Published: February 2025

Abstract
In the mammalian host, Trypanosoma congolense cytoadheres, or sequesters, to the vascular endothelium. Although sequestration influences clinical outcome, disease severity and organ pathology, its determinants and mediators remain unknown. Challenges such as the variability of animal models, the only-recently developed tools to genetically manipulate the parasite, and the lack of physiologically-relevant in vitro models have hindered progress. Here, we engineered brain and cardiac 3D bovine endothelial microvessel models that mimic the bovine brain microvasculature and the bovine aorta, respectively. By perfusing these models with two T. congolense strains, we investigated the roles of flow for parasite sequestration and tropism for different endothelial beds. We discovered that sequestration is dependent on cyclic adenosine monophosphate (cAMP) signalling, closely linked to parasite proliferation, but not associated with parasite transmission to the tsetse fly vector. Finally, by comparing the expression profiles of sequestered and non-sequestered parasites collected from a rodent model, we showed gene expression changes in sequestered parasites, including of surface variant antigens. This work presents a physiologically-relevant platform to study trypanosome interactions with the vasculature and provides a deeper understanding of the molecular and biophysical mechanisms underlying T. congolense sequestration.
No evidence for decision fatigue using large-scale field data from healthcare
Authors: Andersson David , Lindberg Malou , Tinghög Gustav , Persson Emil 
Published: February 2025

Abstract
Decision fatigue is the idea that making decisions is mentally demanding and eventually leads to deteriorated decision quality. Many studies report results that appear consistent with decision fatigue. However, most of this evidence comes from observed sequential patterns using retrospective designs, without preregistration or external validation and with low precision in how decision fatigue is operationalized. Here we conducted an empirical test of decision fatigue using large-scale, high-resolution data on healthcare professionals’ medical judgments at a national telephone triage and medical advice service. This is a suitable setting for testing decision fatigue because the work is both hard and repetitive, yet qualified, and the variation in scheduling produced a setting where level of fatigue could be regarded as near random for some segments of the data. We hypothesized increased use of heuristics, more specifically convergence toward personal defaults in case judgments, and higher assigned urgency ratings with fatigue. We tested these hypotheses using one-sided Bayes Factors computed from underlying Bayesian generalized mixed models with random intercepts. The results consistently showed relative support for the statistical null hypothesis of no difference in decision-making depending on fatigue (BF0+ > 22 for all main tests). We thus found no evidence for decision fatigue. Whereas these results don’t preclude the existence of a weaker or more nuanced version of decision fatigue or more context-specific effects, they cast serious doubt on the empirical relevance of decision fatigue as a domain general effect for sequential decisions in healthcare and elsewhere.
Maternal Oral Reading Expressiveness in Relation to Toddlers' Concurrent Language Skills Across a Continuum of Early Language Abilities
Authors: Zuk Jennifer , Davison Kelsey E. , Doherty Laura A. , Manning Brittany L. , Wakschlag Lauren S. , Norton Elizabeth S. 
Published: February 2025

Purpose:
A rich body of evidence has illuminated the importance of caregivers' use of prosody in facilitating young children's language development. Although caregiver–child shared reading has been repeatedly linked to children's language skills, caregiver prosody during shared reading interactions (i.e., oral reading expressiveness) has been largely overlooked in research to date. Here, we investigated whether maternal oral reading expressiveness is associated with language skills among late-talking and typical-talking toddlers.

Method:

Forty mother–child dyads, with toddlers classified as either late talkers (
n
= 18) or typical talkers (
n
= 22), engaged in a shared reading interaction. Acoustic measures of oral reading expressiveness (mean fundamental frequency [
F
0], rate) were compared between mothers of late versus typical talkers. Whole-group analyses then examined oral reading expressiveness in relation to toddlers' concurrent receptive and expressive language skills across the continuum.

Results:

Between-group comparisons of mothers of late versus typical talkers revealed no group differences in oral reading expressiveness. However, whole-group, continuous analyses of maternal oral reading expressiveness in relation to toddlers' concurrent language skills revealed that maternal oral reading expressiveness, specifically mean
F
0, significantly contributed to the prediction of toddlers' receptive language skills, accounting for demographic and socioeconomic factors.

Conclusions:
Initial findings suggest that maternal oral reading expressiveness is associated with children's emerging language skills and warrant further investigation of how this relates to broader aspects of children's home language environments. This work carries implications for oral reading expressiveness as one facet of shared reading with potential to facilitate early language skill development.
Unveiling first self‐healing in metallised film capacitor: A macro–micro analysis
Authors: He Yushuang , Wang Feipeng , Du Guoqiang , Pan Lei , Li Jian , Yang Hongming , Zhang Xiao , Zhang Zhicheng , Wang Kaizheng 
Published: February 2025

AbstractMetallised film capacitors (MFCs) are renowned for their unique self‐healing (SH) properties, which bestow them with exceptional reliability and stability in the face of intense electric fields, high voltages, and pulse power applications. Nonetheless, the exploration of SH characteristics concerning single‐layer dielectric film remains insufficient for advancing MFC reliability evaluation. To establish the theoretical correlation of SH characteristics from the device to the film in the MFCs, this work developed a simulation model to analyse the SH dynamic behaviour in the MFCs. The effects of coupling capacitors, arc resistance and insulation resistance on the macroscopic characteristics (voltage drop and pulse current) are focused during the SH process in MFCs. The results indicate that SH is primarily associated with the voltage drop duration rather than the sampling current. Consequently, the SH process in MFC is characterised as an abrupt decrease in voltage to its minimum value. This refinement enhances the SH energy dissipation model of MFC. The quantified relationship between the macroscopic characteristics and microstructure evolution (polypropylene decomposition and aluminium electrode vaporisation) is established in MFCs under diverse SH energy levels. As SH energy and duration increase, the proportion of energy attributed to polypropylene decomposition increases, resulting in multi‐layer ablation and adhesion within the metallised film and a pronounced deterioration in MFC electrical performance. The examination of macro–micro perspectives sheds new light on the intricate mechanisms governing the SH behaviour in MFCs, offering valuable insights for the advancement of their design, reliability evaluation, and performance optimisation in diverse electrical applications.