bluuebunny/crossref_metadata_2025_split huggingface dataset:
Acrylic bone cements with bismuth salicylate: Behavior in simulated physiological conditions
Authors: Hernández L. , Vázquez B. , López‐Bravo A. , Parra J. , Goñi I. , Gurruchaga M. 
Published: September 2006

AbstractIn a previous work, we reported the development of acrylic bone cement formulations for application in percutaneous vertebroplasty, by using bismuth salicylate (BS) as the radiopaque agent. Our objective was to obtain high radiopacity along with a therapeutical effect produced by the release of salicylic acid in situ. To follow that study, the setting kinetics and static and dynamical mechanical properties of the BS cements were studied in simulated physiological conditions. Moreover, radiopacity after various times of immersion in saline and the wettability of the cements surfaces were determined. The study finished with the analysis of the biological response. From the results, it can be concluded that physiological conditions did not affect negatively to the cements performance, since all BS‐loaded cements fulfilled the ISO standard requirements. Radiopacity of the formulations was maintained over time and cements with BS were found to be biocompatible. © 2006 Wiley Periodicals, Inc. J Biomed Mater Res, 2007
The β3 chain short arm of laminin‐332 (laminin‐5) induces matrix assembly and cell adhesion activity of laminin‐511 (laminin‐10)
Authors: Nakashima Yukiko , Kariya Yoshinobu , Miyazaki Kaoru 
Published: September 2006

AbstractThe basement membrane (BM) protein laminin‐332 (Lm332) (laminin‐5) has unique activity and structure as compared with other laminins: it strongly promotes cellular adhesion and migration, and its α3, β3, and γ2 chains are all truncated in their N‐terminal regions (short arms). In the present study, we investigated the biological function of the laminin β3 chain. When the β3 chain short arm (β3SA) was overexpressed in HEK293 cells (β3SA‐HEK), they deposited a large amount of β3SA and a small amount of laminin‐511 (Lm511) (laminin‐10) on culture plates. Control HEK293 cells secreted Lm511 but failed to deposit it. The extracellular matrix (ECM) deposited by β3SA‐HEK cells strongly promoted cell attachment and spreading. The β3SA‐HEK ECM did not directly bind Lm511, but it stimulated control HEK293 cells to deposit Lm511 on the culture plates. Although purified β3SA did not support cell adhesion by itself, it enhanced the cell adhesion activity of Lm511. Experiments with anti‐integrin antibodies also suggested that the strong cell adhesion activity of the β3SA‐HEK ECM was derived from the synergistic action of β3SA and Lm511. It has previously been found that β3SA binds an unknown cell surface receptor. Taken together, the present study suggests that the short arm of the laminin β3 chain enhances the matrix assembly of Lm511 and its cell adhesion activity by interacting with its receptor. J. Cell. Biochem. 100: 545–556, 2007. © 2006 Wiley‐Liss, Inc.
Expression profiling of vitamin D treated primary human keratinocytes
Authors: Moll Pamela Renate , Sander Veronika , Frischauf Anna‐Maria , Richter Klaus 
Published: September 2006

AbstractVitamin D has attracted much attention by its ability to stop cell proliferation and induce differentiation, which became of particular interest for the treatment of cancer and psoriasis. We performed an expression profile of 12 hours and 24 hours 1α,25‐dihydroxyvitamin D3 (1α,25(OH)2D3) treated primary human keratinocytes, to determine the changes in gene expression induced by the steroid in order to improve our understanding of the biological activity of 1α,25(OH)2D3. This we expect to be useful for establishing a test system for vitamin D analogs or might open new therapeutic targets or uses for the hormone. For the filter array experiments a non‐redundant set of 2135 sequence verified EST clones was used. The normalized raw data of 2 filters per time point were combined and subjected to SAM analysis to further increase the statistical significance. 86 positive and 50 negative genes were identified after 12 h. The numbers went down to 43 positive and 1 negative gene after 24 h of treatment. Fifteen genes are up‐regulated over a longer period of time (12 h and 24 h). Results were verified by real‐time PCR and/or Northern blots. Targets identified are involved in intracellular signaling, transcription, cell cycle, metabolism, cellular growth, constitution of the extracellular matrix or the cytoskeleton and apoptosis, immune responses, and DNA repair, respectively. Expression profiles showed an initial stop of proliferation and induction of differentiation, and resumed proliferation after prolonged incubation, most likely due to degradation of the hormone. J. Cell. Biochem. 100: 574–592, 2007. © 2006 Wiley‐Liss, Inc.
Torsion of a giant omental cyst mimicking ascites
Authors: Fitoz Suat , Atasoy Cetin , Ekim Mesiha , Yildiz Secil , Erden Ayse , Aktug Tanju 
Published: September 2006

AbstractWe report a case of omental cyst in an 11‐month‐old infant. The cyst occupied nearly the whole abdomen and mimicked massive ascites on sonography. The correct preoperative diagnosis was achieved through the use of CT, and partial torsion of a huge omental cyst was found at surgery. The diagnostic role of sonography and CT in ascites of unknown etiology is emphasized. © 2006 Wiley Periodicals, Inc. J Clin Ultrasound, 2006.
Sonographic appearance of a testicular yolk sac tumor in a 2‐year‐old boy
Authors: Xu Hui‐Xiong , Yi Xian‐Ping 
Published: September 2006

AbstractYolk sac tumor (YST) of testis is the most common of all childhood testicular malignancies. We report a case of testicular YST in a 2‐year‐old boy. The tumor appeared sonographically as an ovoid, homogeneous, well‐circumscribed, isoechoic, solid testicular mass with good sound‐through transmission and increased internal vascularity on color Doppler imaging. The serum alpha‐fetoprotein level was 4,396 ng/ml. Pathological examination confirmed YST at at stage I. Although the sonographic appearance of YST of the testis is nonspecific, the diagnosis is achievable in clinical practice on the combination of elevated serum alpha‐fetoprotein level and sonograms depicting a solid testicular hypervascular mass. © 2006 Wiley Periodicals, Inc. J Clin Ultrasound, 2006.
Clarifying conditions and decision points for mediational type inferences in Organizational Behavior
Authors: Mathieu John E. , Taylor Scott R. 
Published: September 2006

AbstractAlthough mediational designs and analyses are quite popular in Organizational Behavior research, there is much confusion surrounding the basis of causal inferences. We review theoretical, research design, and construct validity issues that are important for drawing inferences from mediational analyses. We then distinguish between indirect effects, and partial and full mediational hypotheses and outline decision points for drawing inferences of each type. An empirical illustration is provided using structural equation modeling (SEM) techniques, and we discuss extensions and directions for future research. Copyright © 2006 John Wiley & Sons, Ltd.
Promoting felt responsibility for constructive change and proactive behavior: exploring aspects of an elaborated model of work design
Authors: Fuller Jerry Bryan , Marler Laura E. , Hester Kim 
Published: September 2006

AbstractAlthough new theoretical models that are suggestive of how work design might be used to foster proactive motivation and proactive performance have been proposed, these models need further elaboration and testing if they are to be useful tools for contemporary organizations. Accordingly, we examine the extent to which feelings of responsibility for constructive change is a proactive psychological mechanism that explains how work design characteristics influence constructive change‐oriented behavior and proactive performance. Specifically, we examine job autonomy, position in the organizational hierarchy, access to resources, access to strategy‐related information, and role ambiguity as antecedents to felt responsibility for constructive change (FRCC). We also examine the extent to which feelings of responsibility for constructive change are positively related to voice behavior (i.e., constructive, change‐oriented communication) and continuous improvement (i.e., proactive role performance). Results indicate hierarchical position and access to resources are positively related to FRCC. Results also indicate proactive personality moderates the relationship between access to resources and FRCC and the relationship between access to strategy‐related information and FRCC. Plots of the interactions reveal that these relationships are enhanced for individuals with proactive personalities. The results also indicate that FRCC is positively related to voice behavior and continuous improvement. Perhaps more importantly, the results suggest that FRCC explains the psychological process by which structural and socio‐structural forces influence proactive behavior. The results are discussed as they pertain to updated work design theory and theories of high involvement work systems, job characteristics, and leadership prototypes. Copyright © 2006 John Wiley & Sons, Ltd.
Managing employee perceptions of the psychological contract over time: the role of employer social accounts and contract fulfillment
Authors: Lester Scott W. , Kickul Jill R. , Bergmann Thomas J. 
Published: September 2006

AbstractThis study proposed and tested relationships pertaining to employee perceptions of psychological contract type over time. Using a longitudinal design, we examined the mediated role that adequacy of social accounts and psychological contract fulfillment play in determining the development of contract perceptions. More specifically, our model posits that perceptions of contract type will influence employee perceptions of the adequacy of social accounts that are offered by the organization and its agents to explain job‐related decisions. These initial perceptions of social accounts at Time 1 were expected to impact perceptions of psychological contract fulfillment at Time 2 (6 months later) and psychological contract fulfillment was proposed to be positively associated with perceptions of a relational psychological contract. Results support the mediating roles of social accounts and psychological contract fulfillment in determining perceptions of contract type over time. Practical implications of these findings and directions for future research are discussed. Copyright © 2006 John Wiley & Sons, Ltd.
Current in vivo wear of metal‐on‐metal bearings assessed by exercise‐related rise in plasma cobalt level
Authors: Khan Munir , Takahashi Tomoki , Kuiper Jan H. , Sieniawska Christine E. , Takagi Katsumasa , Richardson James B. 
Published: September 2006

AbstractBaseline metal ion levels are elevated in patients with metal‐on‐metal (MOM) hip arthroplasty. Interpretation of baseline levels is difficult as measurements are influenced by wear, corrosion, and metal ion release from stored metal in the body. Schmalzried et al. demonstrated that “wear is the function of use, not time.” The specific research question we asked was: Does physiological exercise increase the wear of metal‐on‐metal articulation which can be measured from the plasma metal ion levels? Patients with three different well functioning MOM bearings [two types of resurfacing (BHR 46.8 mm and Cormet 48 mm) and Metasul 28 mm] were included. Blood samples were taken immediately before, immediately after, and 1 h after exercise to determine cobalt and chromium levels. A significant increase (p < 0.005) in serum cobalt and chromium of 13% and 11%, respectively, was noticed after the exercise. Rise of cobalt levels in patients with a resurfacing MOM was 8.5 times (BHR group) or 6.5 times (Cormet group) larger than in those with a Metasul MOM (p = 0.021 and p = 0.047). Neither rise of metal levels nor baseline levels correlated with any other factor (p > 0.27). Exercise‐related elevations of plasma cobalt level provides information on current in vivo wear production that cannot be inferred from a baseline measurement of cobalt levels. Chromium levels cannot provide reliable information on the in vivo wear of the devices. Diameter was the important feature of the implant in determining exercise‐related elevations of plasma cobalt level. Exercise‐related elevations of plasma cobalt level is a potential in vivo tool to understand and improve the tribology of metal–metal bearings. © 2006 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 24:2029–2035, 2006
Unilateral positive–negative myoclonus in Creutzfeldt–Jakob disease
Authors: Ohnari Keiko , Matsunaga Kaoru , Uozumi Takenori , Tamagawa Akira , Hashimoto Tomoko , Tsuji Sadatoshi 
Published: September 2006

AbstractWe report a patient with Creutzfeldt–Jakob disease who presented asymmetric myoclonus. Positive–negative myoclonus was seen only in the right extremities in association with periodic synchronous discharges (PSDs) on the electroencephalogram, although pure positive myoclonus was rarely seen in the left extremities, independently in PSDs. The duration of the silent period recorded in the right‐hand muscle produced by transcranial magnetic stimulation was much longer than that in the left‐hand muscle or that in normal subjects. Brain MRI diffusion‐weighted images showed signal hyperintensities in the putamen and cerebral cortex, including the motor cortex, predominantly on the left side. © 2006 Movement Disorder Society
Intention tremor of the head in patients with essential tremor
Authors: Leegwater‐Kim Julie , Louis Elan D. , Pullman Seth L. , Floyd Alicia G. , Borden Sarah , Moskowitz Carol B. , Honig Lawrence S. 
Published: September 2006

AbstractPatients with essential tremor (ET) have kinetic arm tremor; this tremor can also have an intentional component. We are unaware of reports of intention tremor of the head in ET. Our aims were to describe, provide electrophysiological data and video documentation of, and estimate the prevalence of intention tremor of the head in our sample. Ten (9.0%; 95% confidence interval = 4.7%–14.3%) of 111 patients had intention tremor of the head; in 7 it involved the neck and in 3 the chin. These patients trended toward having more severe kinetic arm tremor and they had more severe intention tremor of the arms. These observations provide further support for the evolving view that the cerebellum may be involved in ET. © 2006 Movement Disorder Society
Prevalence of primary blepharospasm in Sardinia, Italy: A service‐based survey
Authors: Cossu Giovanni , Mereu Alessandra , Deriu Marcello , Melis Maurizio , Molari Andrea , Melis Giannina , Minafra Laura , Pisano Tiziana , Cianchetti Carlo , Ortu Enzo , Sau Gianfranco , Aiello Isidoro , Fresu Miriana , Marrosu Maria Giovanna , Contu Paolo 
Published: September 2006

AbstractWe performed a service‐based epidemiological study of primary blepharospasm in the island of Sardinia (Italy). Due to its favorable geographical location, we are confident we will provide reliable data from patients seeking botulinum toxin treatment. A total of 53 patients were assessed. Prevalence was estimated to be 32.2 per 1 million (95% confidence interval, 23.0–40.8). These results are in line with those obtained in other similar surveys, that is, record‐based, and performed in various European regions such as Northern England, the Munich area, as well as the Epidemiologic Study of Dystonia in Europe. © 2006 Movement Disorder Society
Existence, uniqueness, stochastic persistence and global stability of positive solutions of the logistic equation with random perturbation
Authors: Ji Chunyan , Jiang Daqing , Shi Ningzhong , O'Regan Donal 
Published: September 2006

AbstractThis paper discusses a randomized logistic equation
equation image
with initial value x(0)=x0>0, where B(t) is a standard one‐dimension Brownian motion, and θ∈(0, 0.5). We show that the positive solution of the stochastic differential equation does not explode at any finite time under certain conditions. In addition, we study the existence, uniqueness, boundedness, stochastic persistence and global stability of the positive solution. Copyright © 2006 John Wiley & Sons, Ltd.
Elasto‐plastic model for cement‐treated sand
Authors: Namikawa Tsutomu , Mihira Shingo 
Published: September 2006

AbstractThis paper presents an elasto‐plastic model for non‐linear analyses of cement‐treated sand. Various laboratory tests were systematically carried out to investigate the pre‐peak and post‐peak behaviours of a cement‐treated sand. On the basis of these experimental results, the new model was built within the framework of a relatively simple elasto‐plastic theory.Two failure criteria are employed to express tensile and shear failure characteristics observed in the experimental results of the cement‐treated sand. The proposed model can describe strain‐hardening and strain‐softening responses under both failure modes. In the strain‐softening rules, the smeared crack concept is used, and a characteristic length is considered to avoid the issue of mesh‐size dependency. Since the failure criterion and strain‐hardening/softening rules are based on the experimental evidences, the model is relatively easy to understand and the parameters used in the model have clear physical meaning. The proposed model was applied to simulate the behaviour of cement‐treated sand in various laboratory tests, allowing for a reasonable comprehensive evaluation. It was demonstrated that the proposed model is suitable for describing both the tensile and shear failure behaviours of cement‐treated sand. Copyright © 2006 John Wiley & Sons, Ltd.
No adverse effect of vincristine on handwriting in children after completion of therapy
Authors: Hartman A. , van den Bos C. , van Dartel N. , Stijnen Th. , Pieters R. 
Published: September 2006

AbstractBackgroundLong‐term writing difficulties in children after treatment with vincristine for acute lymphoblastic leukemia, Wilms tumor, B non‐Hodgkin lymphoma, and malignant mesenchymal tumors, were investigated.ProcedureHandwriting of 33 survivors and 33 controls matched for age, sex, and grade, was assessed with the BHK‐scale. The examiner was blinded for whether a child was a case or a control.ResultsNo significant difference in writing speed was found. Mean difference in number of letters produced during 5 min was 6.4 (±67.1, range −103 to +169). No significant difference was found in quality of writing scores; mean difference in points was 1.5 (±7.7, range −19 to +22). Cumulative vincristine dose, age at diagnosis or time since completion of treatment did not affect writing speed or quality.ConclusionChemotherapy, including vincristine, does not lead to long‐term problems in speed or quality of writing in children treated for cancer. Pediatr Blood Cancer 2007;49:841–845. © 2006 Wiley‐Liss, Inc.
Are the new Joint British Societies 2 (JBS 2) targets achievable?
Authors: Balasintharan A , Sahathevan SK , Lasker SS , Chowdhury TA 
Published: September 2006

AbstractThe Joint British Societies 2 (JBS 2) guidelines suggest targets for glycated haemoglobin (HbA1c) (≤6.5%), blood pressure (≤130/80mmHg), total cholesterol (≤4.0mmol/L), and aspirin therapy in patients with diabetes. The aim of this survey was to determine whether patients attending a hospital new patient diabetes clinic achieved these targets one year after referral.We conducted a review of electronic diabetes and primary care records of all patients attending a single consultant‐led new patient diabetes clinic between 1 January and 31 December 2004. Demographic and clinical data at first visit and one year later (HbA1c, blood pressure, total cholesterol, aspirin prescribing) were obtained.In total, 259 patients had full data. The results at one‐year follow up showed: an HbA1c median reduction of ‐1.6% (64.9% achieving HbA1c reduction ≥1%, 54.1% achieving HbA1c ≤7.5%, 20.1% achieving HbA1c ≤6.5%); a median blood pressure reduction of ‐10/6mmHg (81.5% achieving systolic blood pressure [SBP] ≤140mmHg, 43.6% achieving SBP ≤130mmHg); and a median reduction in total cholesterol ‐1.2mmol/L (78.4% achieving total cholesterol ≤5.0mmol/L, 64.1% achieving total cholesterol ≤4.0mmol/L). Aspirin prescribing did not increase between the two visits.It was concluded that improvements in cardiovascular risk factors can be achieved in a hospital diabetic clinic setting, although attainment of targets suggested by the recent JBS 2 guidelines, particularly for glycaemic control and aspirin prescribing, requires significant further effort. Copyright © 2006 John Wiley & Sons, Ltd.
Diagnosing diabetes mellitus: contemporary use of the oral glucose tolerance test in a regional diabetes centre
Authors: Viswanath Ak , Pereira O , Philip S , Mchardy KC 
Published: September 2006

AbstractFollowing considerable debate on whether or not the oral glucose tolerance test (OGTT) should be retained, the revised WHO diagnostic criteria for diabetes recommended its continued use in certain defined circumstances. We have reviewed contemporary use of the OGTT over 12 months in our regional diabetes centre.One hundred and eighty patients underwent an OGTT over a one‐year period. The most common indication was fasting plasma glucose in the 5.5–6.9mmol/L range. Based on the OGTT and prior blood results, nine (5%) had normal carbohydrate tolerance, 40 (22%) had impaired fasting glucose, 52 (29%) had impaired glucose tolerance, and 53 (29.5%) satisfied the criteria for diabetes. Finally, 26 (14.5%) had, by this stage, only a single ‘diagnostic’ glucose value and required further testing. Twelve of these went on to have a second OGTT which confirmed diabetes in three and impaired glucose tolerance in nine. The remaining 14 had further fasting glucose estimations that confirmed diabetes in two cases, were normal in a further two and in the impaired fasting glucose range in 10.The test provided important information on the classification and diagnosis of diabetes. The OGTT continues to have a role in a selected group of patients with fasting blood glucose levels in the uncertain range. The need for a repeat OGTT is likely to increase as more asymptomatic patients are screened earlier in the evolution of glucose intolerance. Copyright © 2006 John Wiley & Sons, Ltd.
Interface properties of an AlN/(AlN)x (SiC)1–x/4H‐SiC heterostructure
Authors: Edgar J. H. , Gu Z. , Gu L. , Smith David J. 
Published: September 2006

AbstractThe crystal structure and compositional changes near the two interfaces of a AlN/(AlN)x (SiC)1–x /4H‐SiC heterostructure prepared by sublimation‐recondensation growth were examined by cross‐sectional transmission electron microscopy. Deposition of an (AlN)x (SiC)1–x layer between a SiC seed and a bulk AlN crystal is potentially beneficial for gradually changing the lattice constants and coefficient of thermal expansion from SiC to AlN. A compositional transition layer adjacent to the 4H‐SiC substrate suggested interdiffusion between the substrate and the alloy layer. The alloy had the 4H‐polytype crystal structure in this layer; above the layer, the alloy exhibited the typical 2H‐polytype. Voids were present at the AlN/(AlN)x (SiC)1–x interface, due to the decomposition of the (AlN)x (SiC)1–x layer before the AlN layer had completely coalesced. The nominally pure AlN layer contained approximately 8% of Si and C, possibly coming from the decomposition of the alloy layer and/or the substrate during growth of the AlN layer. Both interfaces were abrupt, to less than 50 nm, with low densities of threading dislocations. Dislocations in both the (AlN)x (SiC)1–x and AlN layers were not threading, but ran parallel to the (0001) planes. (© 2006 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)