bluuebunny/crossref_metadata_2025_split huggingface dataset:
Prevalence of Risk Factors of Acute Coronary Syndrome in Erbil Cardiac Center: comparing ST-elevation with non ST-elevation Acute Coronary Syndrome
Authors:   MBChB. DM. MRCP. Senior house officer (SHO interventional cardiology) at Erbil cardiac center., Qader Omar Hama Radha , Saka Mariwan ,   MBChB, FICMS (med), High Diploma (Int. Cardiology), Erbil cardiac center. Associate Professor Hawler Medical university
Published: March 2024

Background and objectives: Acute coronary syndrome is the leading cause of death all over the world, there are many different risk factors as important etiology for this acute condition, this syndrome has been studied in different countries with a variety of results. The aim was to define different risk factors for the patients admitted to Erbil cardiac center and to find out the most common of these factors and the relationship between different clinical types of this syndrome (namely ST-elevation myocardial infarction, non-ST elevation myocardial infarction/unstable angina) with varying types of risk factors. Methods: This was a cross-sectional descriptive nonrandomized study that included 100 patients with acute coronary syndrome, mean age of 57.5, the age range of 27—90 years, the majority of patients were male (78%), all patients were interviewed and investigated properly, and according to coronary angiographic findings treated by percutaneous coronary intervention or surgery. Results: The prevalence of acute coronary syndrome was significantly higher in male gender, the commonest risk factor was overweight and obesity 77% , followed in reduced frequency by other risk factors, More than half of patients(58.6%)with ST-elevation myocardial infarction were≤55years age, while 66.7% of patients with non ST-elevation myocardial infarction were >55years age. The most common artery involved was the left anterior descending artery, significant number 26.2% of non ST- elevation myocardial infarction/UA patients had three vessel stenosis and higher number34.5% of ST- elevation myocardial infarction patients had right coronary artery stenosis. Conclusions: The most common risk factor was overweight and obesity, no significant relation between clinical types and risk factors, low number of unstable angina cases seen in the emergency unit.
Ultrasonographic Picture Of The Skin And Subcutaneous Tissue In The Treatment Of Cellulite Using The Compressive Microvibration®
Authors: Kardashova Z. Z. , Selezneva E. V. , Vasilenko N. A. , Vasilenko I. A. , Saggini R. , Bacci P. A. 
Published: March 2024

In recent years, the demand for non-invasive methodologies in aesthetic medicine for treating localized adiposity, cellulite, and sagging skin has increased significantly, particularly the demand for massage techniques with mechanical vibrations. The aim of the present study is to evaluate the effectiveness of Compressive Microvibration® in reducing the expression of cellulite and improving skin conditions in women of different ages under ultrasound control during 60 days of observation. A prospective, single-center, nonrandomized study enrolled 27 women with mild to moderate gynoid lipodystrophy, aged 40 to 69 years, who have been subject to twelve sessions of Compressive Microvibration® (Endospheres®). A specialized high-resolution digital ultrasound system, the DUB SkinScanner (tpm GmbH, Germany), has been used to visualize the skin. Also, the sample anthropometric parameters have been measured, the body mass index has been calculated, and photographs have been taken. In the patients included in the study, in all age groups, after complete treatment of Endospheres®, a decrease in BM has been noted, with a reduction of the bitrochanteric and hip circumference. An improvement in the morphological topography of the skin in terms of regularization of skin irregularities, leveling of reliefs, reduction of depressions, and increase in skin elasticity and density has also been recorded. After a cycle of therapy on the anterior surface of the abdomen and the thigh anterior and posterior surfaces, the scannograms revealed a decrease in the thickness of the epidermis at various levels, the resolution of the phenomenon of hyperkeratosis, a compaction of the dermis, and an increase in its homogeneity and echogenicity. The effect obtained was still present during a control examination two months after the conclusion of the treatment. The analysis of the dynamics of ultrasound criteria demonstrated the effectiveness of the Compressive Microvibration® in women with mild to moderate gynoid lipodystrophy to improve their skin conditions and maintain the obtained effect for 2 months of observation without unwanted side complications.
CLINICAL AND IMMUNOLOGICAL ASPECTS OF PERIPHERAL NERVOUS SYSTEM LESIONS IN SYSTEMIC LUPUS ERYTHEMATOSUS IN ADULTS
Authors: Юркин А.К. , Юркина Е.А. , Жигулина А.И. , Федорец В.Н. 
Published: March 2024

Системная красная волчанка относится к тяжелым инвалидизирующим аутоиммунным заболеваниям с вовлечением в патологический процесс различных органов и систем, в том числе с возможным многоуровневым поражением нервной системы. Неврологические аспекты системной красной волчанки, особенно в отношении периферической нервной системы, остаются наименее изученными, их отличает значительная вариабельность клинических проявлений. Как показал анализ научных публикаций, патогенез периферических невропатий до конца не изучен, но, вероятно, имеет значение совокупность расстройств иммунорегуляции, часть из которых может быть генетически детерминирована. Это во многом объясняет трудности диагностики, требует дальнейших исследований с целью усовершенствования методов ранней верификации неврологических нарушений при системной красной волчанке, имеющих значение для прогноза и качества жизни данной категории пациентов.
Systemic lupus erythematosus is a severe disabling autoimmune disease with involvement of various organs and systems in the pathological process, including possible multilevel damage to the nervous system. Neurological aspects, especially in relation to the peripheral nervous system, systemic lupus erythematosus remain the least studied, they are distinguished by a significant variability in clinical manifestations. As the analysis of scientific publications has shown, the pathogenesis of peripheral neuropathies has not been fully studied, but it is likely that a combination of immunoregulatory disorders is important, some of which can be genetically determined. This largely explains the difficulties of diagnosis, requires further research to improve the methods of early verification of neurological disorders in systemic lupus erythematosus, which are important for the prognosis and quality of life of this category of patients.
HEPATOTOXIC EFFECT AND METABOLISM OF ANTI-TUBERCULOSIS DRUGS
Authors: Суханов Д.С. , Алексеева Ю.С. , Тимофеев Е.В. 
Published: March 2024

В обзорной статье рассмотрены современные аспекты печеночного метаболизма применяемых в настоящее время противотуберкулезных препаратов первого, второго и третьего ряда. Показаны возможные варианты генетического полиморфизма ферментов I и II фаз биотрансформации лекарственных препаратов и его влияние на частоту возникновения лекарственно-индуцированных поражений печени. Рассмотрена частота гепатотоксических реакций на фоне терапии лекарственными средствами в составе режимов химиотерапии, применяемых для лечения туберкулеза. Проанализированы данные о тяжести поражений печени и характере преобладающего биохимического синдрома (цитолитический, холестатический и смешанный варианты) в зависимости от используемого препарата. Особый акцент сделан на влиянии на печень новых противотуберкулезных лекарственных средств — бедаквилина, линезолида и деламанида. Выявлены препараты, имеющие максимальный риск лекарственной гепатотоксичности (изониазид, рифампицин, пиразинамид, ПАСК, амоксициллин/клавуланат), а также противотуберкулезные лекарственные средства с недоказанным негативным влиянием на печень (линезолид и деламанид). Сделан вывод о необходимости дальнейшего изучения метаболизма противотуберкулезных препаратов и его влияния на частоту лекарственных поражений печени с целью своевременного мониторинга побочных эффектов лекарственной терапии и их профилактики.
The review article discusses modern aspects of hepatic metabolism of currently used anti-tuberculosis drugs of the first, second and third series. Possible variants of genetic polymorphism of enzymes of phases I and II of biotransformation of drugs and its effect on the incidence of drug-induced liver lesions are shown. The frequency of hepatotoxic reactions against the background of drug therapy as part of chemotherapy regimens used to treat tuberculosis is considered. The data on the severity of liver lesions and the nature of the predominant biochemical syndrome (cytolytic, cholestatic and mixed variants), depending on the drug used, were analyzed. Special emphasis is placed on the effect on the liver of new anti–tuberculosis drugs — bedaquiline, linezolid and delamanid. Drugs with the highest risk of drug hepatotoxicity (isoniazid, rifampicin, pyrazinamide, PASC, amoxicillin/clavulanate), as well as anti-tuberculosis drugs with an unproven negative effect on the liver were identified (linezolid and delamanid). It is concluded that it is necessary to further study the metabolism of anti-tuberculosis drugs and its effect on the frequency of medicinal liver lesions in order to timely monitor the side effects of drug therapy and their prevention.
Pentingnya Keterampilan Retorika Da’i di Era Society 5.0 dalam Efektivitas Keberhasilan Dakwah Kepada Mad’u
Authors: Umi Khofifah 
Published: March 2024

The era of society 5.0 is an era where almost all human work is assisted by sophisticated machines or technology that makes it easier for humans to do their jobs. In this era of all-technology, preachers are required to have rhetorical skills and a qualified ability to use technology as a medium in conveying tausyiah or da'wah to mad'u. Skills in using technology will pave the way for preachers to be more flexible in conveying their da'wah without fear of being limited by space and time. Da'wah skills on social media can take the form of interesting writing or videos that make mad'u interested in reading and watching what the preachers convey where this is the key to how effective the da'wah delivered to mad'u is.
Keyword :Era of society 5.0, skills, effectiveness
Efektivitas Majelis Taklim Al-Istiqomah untuk Mempererat Ukhwah Masyarakat Desa Wangandowo Kecamatan Bojong Kabupaten Pekalongan
Authors: Fa'izah Anisatul , Eliana Dita , Auliya Rizka 
Published: March 2024

Dalam kehidupan sosial, masyarakat memiliki peran penting dalam kehidupannya. Sebagai makhluk sosial, masyarakat tentu memerlukan interaksi dengan masyarakat lainnya dalam menjalankan aktivitas sehari-harinya. Kehidupan sosial biasa kita temui dalam lingkungan masyarakat agar kehidupan sosial dalam lingkungan masyarakat tidak terjadi pertikaian yang tidak diinginkan, kita sebagai masyarakat mempunyai hak dalam menciptakan kehidupan bermasyarakat yang tentram, menjaga kedamaian dan kekompakan, salah satunya dengan mengikuti kegiatan majelis taklim yang ada hadir ditengah masyarakat. Majelis taklim hadir ditengah masyarakat salah satu upaya dalam meminimalisir perselisihan antar masyarakatnya. Dalam penelitian kali ini, kami ikut serta hadir mengikuti pengajian ibu-ibu majelis taklim Al-Istiqomah Di Desa Wangandowo, Kecamatan Bojong, Kabupaten Pekalongan.Metode penelitian yang kami lakukan adalah metode kualitatif deskriptif yaitu dengan prosedur mengumpulkan data melalui pengamatan langsung dilapangan,dokumentasi,dan interview. Dan berdasarkan hasil dari penelitian kami, diperoleh bahwa jamaah pengajian ibu-ibu Al Istiqomah mempunyai agenda kegiatan tahunan bahkan kegiatan yang akan diselenggarakan. Kegiatan majelis taklim Al-Istiqomah ini diharapkan bisa menjadi wadah masyarakat untuk menjaga kerukunan dan menjalin ukhuwah islamiyyah yang lebih erat. Isi dari pembahasan ini tentang kegiatan yang ada didalam majelis taklim dan permasalahan pada tingkat partisipasi dari jamaah dalam mengunjungi pengajian rutinan majelis taklim al – istiqomah desa wangandowo.
The Role of Surface Modification Methods for Sustainable Textiles
Authors: Korkmaz Gürsel , Kılınç Mehmet , Kılınç Nur , Dilek Kut Y. 
Published: March 2024

Sustainability aims to provide a livable future for the next generations. Studies on reducing high chemical, energy, and water consumption make significant contributions to sustainability in many sectors. The textile sector consists of many processes such as fiber production, yarn and fabric production, dyeing, and finishing processes. Each of these processes consumes a significant amount of water and energy. Cotton fiber production consumes approximately 1559 kg of fresh water per kg, and polyester fiber production consumes approximately 108 kWh of electricity per kg. Clean water consumption can be up to 200 L/kg in subsequent processes such as bleaching, dyeing, printing, and finishing. Surface modification techniques in textile production can play a role in sustainability, especially in areas such as reduction, reuse, and recycling. In this chapter, we aim to investigate the effects of surface modification techniques on reducing chemical, energy, and water consumption in textile production, improving textile performance properties, and altering the service life of textiles.
Üniversite Öğrencilerinin Yeme Farkındalığının, Beslenme Bilgi Düzeylerinin ve Vegan-Vejetaryen Beslenme Algısının Değerlendirilmesi
Authors: ÖZGÜR Mustafa , KAYAÇELİK Dilek , KAHRAMAN Ayşe Nur , TERZİ TOPAL Feyza 
Published: March 2024

Amaç: Bitki ağırlıklı beslenmeye dayanan diyetler vegan/vejetaryen diyetler olarak tanımlanır. Bu araştırma Burdur Mehmet Akif Ersoy Üniversitesi öğrencilerinin yeme farkındalığının vegan-vejetaryen beslenmeye bakışı ve beslenme bilgi düzeylerinin değerlendirilmesi amacıyla yapılmıştır.
Bireyler ve Yöntem: Kesitsel analitik tipte planlanan çalışmaya, Burdur Mehmet Akif Ersoy Üniversitesi’nde eğitim gören 144 kadın 22 erkek öğrenci olmak üzere toplam 166 öğrenci katılmıştır. Anket formunda öğrencilerin sosyo-demografik bilgileri alınmış, öğrencilerin beslenme bilgi düzeyleri ve yeme farkındalıkları ‘Yetişkinler İçin Beslenme Bilgi Düzeyi Ölçeği’ ve ‘Yeme Farkındalığı Ölçeği’ ile belirlenmiş ve vegan-vejetaryen beslenmeye yönelik bakış açıları sorgulanmıştır.
Bulgular: Verilerin analizi sonucunda kadınların yaş ortalaması 21,0±3,0 yıl iken erkeklerin yaş ortalaması 23,0±5,3 yıl olduğu tespit edilmiştir. Temel beslenme ve besin-sağlık bilgisi alt boyutundan kadın öğrenciler (52,1±9,0), erkek öğrencilere (45,7±7,0) kıyasla daha yüksek puan almıştır (p0,05).
Sonuç: Kadın öğrencilerin erkek öğrencilere kıyasla daha yüksek beslenme bilgisine sahip ve yeme farkındalıklarının yüksek olduğu saptanmıştır, aynı zamanda vegan-vejetaryen beslenme bilgi düzeyleri kadın öğrencilerde daha yüksektir.
MODELOS Y TIPOS EN LA ARAUCANÍA, CHILE. Estrategias y políticas de estandarización arquitectónica para una ocupación situada,1886-1931
Authors: Fuentes Hernández Pablo 
Published: March 2024

The Araucania, in southern Chile, which divided the country in two, was a territory inhabited by the Mapuche people since ancient times. At the end of the 19th and beginning of the 20th century, the State launched a military and civil occupation policy that would expand Republican ideals under capitalist concepts. In this way, the occupation strategies tried to consolidate modernizing processes. In the state approach of some of the Presidents of the time, there were several relevant actions: railroad expansion, land division, city creation, colonization, and the displacement of the Mapuche people to indigenous reservations. Among the architectural events that reveal the willingness to consolidate the nation-state, the construction of modern school establishments is seen as a civilizing trigger. This work aims to present the architectural alternatives chosen by the State to impose its official presence, while new languages of political aestheticization spread.

Keywords: Araucanía, nation state, school buildings, standardization.
La Araucanía, en el sur de Chile, era un territorio habitado desde tiempos ancestrales por el pueblo mapuche que dividía al país en dos. A fines del siglo XIX y comienzos del XX el Estado emprendió una política de ocupación militar y cívica que expandía ideales republicanos amparado en conceptos capitalistas. Así, las estrategias de ocupación intentaban consolidar procesos modernizadores. En el enfoque estatal de algunos presidentes de la época se advierten algunos hechos relevantes: la expansión ferroviaria, la hijuelación del territorio, la creación de ciudades, la colonización y el desplazamiento de mapuches a reducciones indígenas. Entre los hechos arquitectónicos que revelan la voluntad por consolidar el estado nación se aprecia la construcción de establecimientos escolares modernos como detonadores civilizatorios. El propósito de este trabajo es presentar las alternativas arquitectónicas escogidas por el Estado para imponer su presencia oficial, al tiempo que expande nuevos lenguajes propios de una estetización política.

Palabras clave: Araucanía, estado nación, construcciones escolares, estandarización.
Pengembangan Media Ajar Kartu Semesta utuk Memperkaya Glosarium Siswa SMA pada Mata Pelajaran Biologi
Authors: Larasati Eva 
Published: March 2024

Abstract
Biology education plays a crucial role in shaping students' understanding of the fundamental scientific concepts underlying life. Glossaries, as collections of terms and their definitions, play a central role in facilitating students' comprehension of complex biological terminology. However, the current practices in high school biology education often rely heavily on textbooks, resulting in monotonous and less engaging learning experiences. This research aims to develop a universe-themed learning media as an alternative to enrich high school biology glossaries. Employing the 4-D development model, the study involves in-depth curriculum analysis, design, and the development of learning media. As a result, 40 glossaries have been generated with symbolic dimensions to enhance students' holistic understanding of life and the universe. Although not yet at the dissemination stage, the potential of this media in Biology education, both online and offline, shows promising prospects. Research recommendations include expanding trials with more diverse student groups and adding dissemination stages to enhance the validity and effectiveness of universe-themed learning media in high schools. It is anticipated that these steps will strengthen the contribution of the learning media in enriching biological concepts understanding and improving the quality of high school biology education.
Abstrak
Pendidikan biologi memegang peranan penting dalam membentuk pemahaman siswa terhadap konsep-konsep ilmiah yang mendasari kehidupan. Glosarium, sebagai kumpulan kata dan pengertiannya, memiliki peran sentral dalam memfasilitasi pemahaman siswa terhadap terminologi biologi yang kompleks. Meskipun demikian, praktik pembelajaran biologi di tingkat Sekolah Menengah Atas (SMA) masih sering mengandalkan buku sebagai media utama, yang cenderung monoton dan kurang menarik. Penelitian ini bertujuan mengembangkan media pembelajaran berbasis kartu semesta sebagai alternatif yang dapat memperkaya glosarium biologi siswa SMA. Dengan menggunakan model pengembangan 4-D, penelitian ini melibatkan analisis mendalam terhadap kurikulum, perancangan, dan pengembangan media pembelajaran. Hasilnya, 40 glosarium telah dihasilkan dengan dimensi simbolis yang dapat memperkaya pemahaman siswa terhadap kehidupan dan alam semesta secara holistik. Meskipun belum sampai tahap penyebaran, potensi media ini dalam pembelajaran Biologi, baik daring maupun tatap muka, menunjukkan janji yang besar. Saran penelitian mencakup perluasan uji coba dengan kelompok siswa yang lebih besar dan beragam, serta penambahan tahapan penyebaran untuk meningkatkan validitas dan efektivitas media pembelajaran berbasis kartu semesta di tingkat SMA. Diharapkan, langkah-langkah ini dapat memperkuat kontribusi media pembelajaran tersebut dalam memperkaya pemahaman konsep biologi dan meningkatkan kualitas pembelajaran di tingkat SMA
Bauran Promosi Terhadap Keputusan Pembelian di Warunk Upnormal Ciumbuleuit Kota Bandung
Authors: Legistari Kartika 
Published: March 2024

Penelitian ini bertujuan untuk mengetahui pengaruh Bauran promosi tergadap keputusan pembelian di Warunk Upnormal Ciumbuleuit Kota Bandung, dimana diketahui terdapat tingkat penjualan produk yang tidak stabil dan cenderung pada bulan bulan tertentu di tahun 2023 menurun, dugaan penurunan penjulan tersebut karena penerapan bauran promosi yang kurang maksimalPenelitian ini menggunakan metode Kuantitatif, dan untuk menjelaskan secara jelas hasil penelitian digunakan deskriftif dengan menggunakan sample sebnayak 41 orang dari jumlah populasi sebanyak 714 orang sehingga secara keseluruhan penelitian ini menggunakan metode kuantitatif Deskriptisdiketahui bahwa setiap penambahan 1% Bauran Promosi maka Keputusan Pembelian akan meningkat sebesar 0.534,Jika di bandingkan dengan nilai Sig. dengan nilai probobalitas 0.05 dan nilai koefisien determinasi R Square adalah sebesar 0.291 atau sama dengan 29.1% yang benilai . Angka tersebut mengandung arti bahwa variabel Bauran Promosi berpengaruh terhadap variabel Keputusan Pembelian sebesar 29.1%. Sedangkan sisanya dipengaruhi oleh faktor lain Keputusan Pembelian terhadap Produk Warungk Upnormal Ciumbuleuit, Kota Bandung. Rata-rata konsumen sebagian besar diakibatkan karena tempat dan suasana Restoran yang nyamam dan harga yang terjankau serta banyak Promo yang didapat. Dari perhitungan statistik menggunakan analisis Determinasi diketahui bahwa bauran promosi Mempengaruhi Keputusan Pembelian
Sosialisasi Klinis Hukum Terkait Dengan Kerugian Kepentingan Negara
Authors: Ginting Yuni Priskila , Ozora Abednego , Santoso Fasya Tasya Mersilya , Sadikin Jessica Marcella , Marceliani Rachelina 
Published: March 2024

Penelitian ini ditujukan untuk membahas kerugian kepentingan negara yang berfokuskan pada eksplorasi isu-isu yang berkaitan dengan implementasi dan kedudukannya dalam klinis hukum. Kerugian negara menurut Undang - Undang Nomor 1 Tahun 2004 tentang Perbendaharaan Negara meliputi kekurangan uang, surat berharga, dan barang, yang nyata dan pasti jumlahnya sebagai akibat perbuatan melawan hukum baik sengaja maupun lalai. Sedangkan klinis hukum sendiri adalah mata kuliah yang dimaksudkan untuk memperkaya ilmu pengetahuan (knowledge), keahlian (skill), dan rasa keadilan sosial (sense of justice). Dalam penelitian ini, analisis mendalam terhadap aspek dan unsur kerugian negara sebagai kedudukannya dalam klinis hukum. Dengan ini, penelitian diharapkan mampu memberi wawasan dan bahan riset dalam menghindari dan mengatasi masalah kerugian negara demi terciptanya sistem pemerintahan yang transparan dan Indonesia yang harmonis.