bluuebunny/crossref_metadata_2025_split huggingface dataset:
Knee malalignment and laterality influence 2‐year meniscus tear repair outcomes: A pilot study
Authors: Tschopp Benjamin , Omoumi Patrick , Nyland John , Chaouch Aziz , Schneebeli Valentine , Jakob Roland , Martin Robin 
Published: February 2025

AbstractPurposeTo analyse biomechanical determinants for radiological and clinical outcomes of posterior horn longitudinal vertical meniscal tear (LVMT) repairs.MethodsPatients undergoing primary repair of vascular zone traumatic full‐thickness posterior horn LVMT were enroled. We hypothesized four potential factors would influence mid‐term outcomes: malalignment (varus/valgus ≥5° for medial/lateral tears), meniscal laterality (medial vs. lateral), concomitant anterior cruciate ligament reconstruction (ACLR) and cartilage damage (Outerbridge grade ≥ II). The primary outcome was posterior horn nonhealing rate 6 months postoperatively (T1), evaluated using computed tomography arthrography (CTA) and Henning's criteria. Secondary outcomes were patient‐reported outcomes measures (PROMs) assessed at T1 and ≥24 months postoperatively (T2). Univariate and multivariate logistic regression models estimated the marginal relative risk (MRR) of nonhealing for each determinant, while fractional logit regression assessed determinants' impact on PROMs at T1 and T2.ResultsSeventy‐eight patients (median age 29 years, interquartile range [IQR]: [21–37]); 76% male), were followed for ≥2 years (median 2.5 years, IQR: [2.1–3.6]). LVMTs extended to the middle horn in 81% and to the anterior horn in 52%. Posterior horn nonhealing rates (53%) were higher than in the middle (35%, p = 0.013) and anterior horn (7%, p < 0.001). Malalignment was present in 14%, medial meniscal involvement in 77%, ACLR in 55% and cartilage damage in 37%. Malalignment (MRR = 1.48, 95% confidence interval (CI): [0.84, 2.09]) and medial laterality (MRR = 1.7, 95% CI: [0.93, 3.6]) were independently identified as potential nonhealing risk factors. But it is the combination of varus malalignment and medial laterality that significantly increased the risk of nonhealing (MRR = 2.54, 95% CI: [1.09, 6.01], p = 0.033) and negatively impacted all Knee Injury and Osteoarthritis Outcome Score (KOOS) subscales and International Knee Documentation Committee (IKDC) score at T1 and/or T2.ConclusionCombined varus malalignment and medial meniscus involvement strongly predicted repair nonhealing and poorer outcomes after posterior horn LVMT repair.Study DesignProspective cohort pilot study.Level of EvidenceLevel III.
Adjusted ∆NBR Index Thresholds for Forest Fire Severity Mapping: A Study in Central Amazonia
Authors: Pacheco Ramos Camila Julia , Graça Paulo Maurício Lima de Alencastro , Fearnside Philip Martin 
Published: February 2025

ABSTRACTThe 2006 study of fire severity in coniferous forest by Key and Benson derived threshold values of the Delta Normalized Burn Ratio (∆NBR) for interpreting satellite imagery of fire scars, and ∆NBR has been widely used for forest fire severity worldwide. We hypothesized that these thresholds underestimate the severity of fires of tropical forests. Our goal was to find appropriate thresholds to map fire severities in the central Amazon and evaluate trends in recent years. These forests are increasingly threatened by deforestation, severe droughts and wildfires. We adjusted the ∆NBR decision thresholds using new methods that are relatively fast and cheap, with a combination of field data, hemispherical photographs of the opening of the forest canopy with different fire severities, and the use of Landsat data for fires that occurred in 2015 images. The agreement between the classification of severity in the field and the classification by the adjusted ∆NBR thresholds was satisfactory (overall accuracy = 74.2%; Kappa coefficient = 0.635). Using the Key & Benson thresholds resulted in a Kappa value of only 0.184, and the severity classification would be underestimated. We applied the new threshold values to map forest fire severity in the central Amazon from 1995 to 2017. The year 2015 had the greatest area of fire, of which 60.7% was classified as moderate, 19% as high, and 20% as low severity. The results corroborate the importance of adjusting decision thresholds for each study area to classify fire severity using ∆NBR.
A comprehensive analysis of MRI‐related Cochlear implant adverse events reported by FDA's manufacturer and user facility device experience database
Authors: Lin Amy , Menta Arjun K. , Ahmad Syed Ameen , Zhang Aileen , Perdomo Dianela , Reddy Ashwin , Ward Bryan K. 
Published: February 2025

AbstractObjectiveIdentify MRI‐related cochlear implant (CI) adverse events from the Food and Drug Administration (FDA) Manufacturer and User Facility Device Experience (MAUDE) database and determine whether devices with diametric magnets are associated with reduced adverse events.MethodsData on MRI‐related adverse events were collected from the MAUDE database for reports filed between 01/01/2013 and 01/29/2023. Outcomes and interventions were manually extracted. Device problems, electrode designs, and correlated patient problems were grouped and analyzed using R.ResultsAll CI complications were derived from three manufacturers: Cochlear Limited, Advanced Bionics, and MED‐EL. MRI‐related CI complications occurred in 668 of 32,446 reports (2.1%). MRI‐related CI complications increased from 32 reports (4.8%) in 2013 to a peak of 142 reports (21.3%) in 2019 and decreased to 56 reports (8.4%) in 2022. The most common MRI‐related device problems were dislodgment/dislocation (39.9%, n = 266) or migration/expulsion (33.4%, n = 223). The most frequently identified patient problems identified were pain (31.6%, n = 211), hearing impairment (4.9%, n = 33), unspecified medical problems (3.7%, n = 25), implant failure (3.0%, n = 20), and injury (1.5%, n = 10). Of these, 358 reports (53.6%) contained the date of device manufacture. The median MDR per year decreased from 11 in the 3 years before each manufacturer released their MRI‐conditional CI to 0 in the 3 years following the release (p = 0.014).ConclusionsThe introduction of MRI‐conditional CIs has successfully reduced MRI‐associated adverse events. There have been no reported cases of MRI‐related CI complications for devices containing the new MRI‐conditional magnets for each of the three major US manufacturers.Level of evidenceN/A
Development of a Clinical Prediction Model to Predict Malignant Transformation of Sinonasal Inverted Papilloma Based on Hematological Indices and Clinical Features
Authors: Sun Kai , Wu Ce , Zhang Zengxiao , Chen Jiahong , Yan Xudong , Li Shunke , Wang Lin , Yu Longgang , Jiang Yan 
Published: February 2025

ABSTRACTObjectiveSinonasal inverted papilloma (SNIP) has a risk of malignant transformation into SNIP with squamous cell carcinoma (SNIP‐SCC). Early detection of SNIP‐SCC is crucial for patient outcomes. This study aimed to evaluate the utility of tumor‐related hematological indices in the early diagnosis of SNIP‐SCC and to develop a nomogram incorporating imaging and clinical features.MethodsThis study included 159 patients with SNIP with (n = 34) or without (n = 125) SCC. Univariate and multivariate logistic regression analyses were employed to identify independent risk factors and develop nomogram. The diagnostic model was evaluated using receiver operating characteristics (ROC), standard, clinical decision, and clinical impact curves.ResultsElevated serum cytokeratin fragment antigen 21‐1 (CYFRA 21‐1), the loss of convoluted cerebriform pattern, bone destruction, headache/facial pain, and epistaxis/blood‐tinged mucus were identified as independent risk factors for SNIP‐SCC. The optimal cut‐off value for serum CYFRA 21‐1 was 3.51 ng/mL, with the nomogram area under the ROC curve of 0.966 based on the above indicators.ConclusionThe findings suggest that CYFRA 21‐1 is a promising diagnostic marker for SNIP‐SCC. The nomogram incorporating serum CYFRA 21‐1, imaging features, and clinical factors demonstrates strong clinical utility and can be a reference tool for clinical decision‐making.
Lake chlorophyll responses to drought are related to lake type, connectivity, and ecological context across the conterminous United States
Authors: Sun Xinyu , Cheruvelil Kendra S. , Hanly Patrick J. , Soranno Patricia A. 
Published: February 2025

AbstractLocal and regional‐scaled studies point to the important role of lake type (natural lakes vs. reservoirs), surface water connectivity, and ecological context (multi‐scaled natural settings and human factors) in mediating lake responses to disturbances like drought. However, we lack an understanding at the macroscale that incorporates multiple scales (lake, watershed, region) and a variety of ecological contexts. Therefore, we used data from the LAGOS‐US research platform and applied a local water year timeframe to 62,927 US natural lakes and reservoirs across 17 ecoregions to examine how chlorophyll a responds to drought across various ecological contexts. We evaluated chlorophyll a changes relative to each lake's baseline and drought year. Drought led to lower and higher chlorophyll a in 18% and 20%, respectively, of lakes (both natural lakes and reservoirs included). Natural lakes had higher magnitudes of change and probabilities of increasing chlorophyll a during droughts than reservoirs, and these differences were particularly pronounced in isolated and highly‐connected lakes. Drought responses were also related to long‐term average lake chlorophyll a in complex ways, with a positive correlation in less productive lakes and a negative correlation in more productive lakes, and more pronounced drought responses in higher‐productivity lakes than lower‐productivity lakes. Thus, lake chlorophyll responses to drought are related to interactions between lake type and surface connectivity, long‐term average chlorophyll a, and many other multi‐scaled ecological factors (e.g., soil erodibility, minimum air temperature). These results reinforce the importance of integrating multi‐scaled ecological context to determine and predict the impacts of global changes on lakes.
Bright Heralded Single‐Photon Source Saturating Theoretical Single‐photon Purity
Authors: Wang Haoyang , Yuan Huihong , Zeng Qiang , Zhou Lai , Ma Haiqiang , Yuan Zhiliang 
Published: February 2025

AbstractSingle‐photon source is the cornerstone for modern quantum information processing. The present work derives the theoretical limit of single‐photon purity for general parametric heralded single‐photon sources, and subsequently demonstrates a bright, gigahertz‐pulsed heralded source with the purity saturating the limit. By stimulating spontaneous four‐wave mixing effect in the silicon spiral waveguide, this on‐chip source is measured to have a coincidence rate exceeding 1.5 MHz at a coincidence‐to‐accidental ratio (CAR) of 16.77 in the photon pair correlation experiment. The single‐photon purity of this source, quantified by the heralded auto‐correlation function , is measured by a heralded Hanbury Brown–Twiss setup to reach the theoretical limit with the lowest value of obtained at a coincidence rate of 0.8 kHz and a CAR of 2220. The performance improvements are attributed to effective spectral filtering suppressing the noise as well as the coherent pump condition helped by optical injection locking. The reported results provide a reliable standard for benchmarking heralded single‐photon sources and present a state‐of‐the‐art heralded source for quantum information processing.
Approximation of skew Brownian motion by snapping‐out Brownian motions
Authors: Bobrowski Adam , Ratajczyk Elżbieta 
Published: February 2025

AbstractWe elaborate on the theorem saying that as permeability coefficients of snapping‐out Brownian motions tend to infinity in such a way that their ratio remains constant, these processes converge to a skew Brownian motion. In particular, convergence of the related semigroups, cosine families, and projections is discussed.
Synthesis of FeSiAl/SrFe12O19 soft magnetic composite materials with low magnetic loss
Authors: Su L. , Wang P. , Yu C. Y. , Tao L. P. , Shu S. Z. 
Published: February 2025

AbstractFeSiAl/SrFe12O19 soft magnetic composite material was prepared by mechanically crushing FeSiAl powder and M‐type permanent magnet hexagonal ferrite powder according to a certain quality. Their structures, morphologies, and magnetic properties were studied using x‐ray diffraction (XRD), scanning electron microscopy (SEM), energy dispersive spectroscopy (EDS), SQUID, and B−H analyzers. Compared to organic and other inorganic composite materials, SrFe12O19 has a higher thermal decomposition temperature. The x‐ray diffraction pattern indicates that SrFe12O19 phase was detected in the sample. Scanning electron microscopy (SEM) and energy dispersive spectroscopy (EDS) images show that powdered SrFe12O19 is dispersed on the surfaces and gaps of particles of different sizes. The magnetic analysis results indicate that although SrFe12O19 increases the hysteresis loss of the material, its good insulation reduces eddy current loss. When the content of SrFe12O19 is 2 wt.‐%, the magnetic loss is the lowest. The lower magnetic loss and higher thermal decomposition temperature of this composite material make it have a wider range of application prospects.
Hardness enhancement of commercially pure aluminium by a typical cyclic heat treatment process involving repeated ice‐brine quenching
Authors: Maity J. , Bansfore A. S. , Pal A. , Hazra B. , Roy L. , Mahato D. , Shav A. B. 
Published: February 2025

AbstractA typical cyclic heat treatment process has been adopted up to four cycles on initially annealed commercially pure aluminium, primarily containing iron impurity, that involves short‐duration (5 minutes) holding at 600 °C followed by ice‐brine quenching in each cycle. As a consequence, a significant grain refinement effect and a gradual accumulation of lattice strain during the progress of cyclic heat treatment are observed in relation to an evolution of the regions of extremely low misorientation angle in the aluminium matrix. Apart from quench‐in strain, the presence of grain boundary iron aluminide phase, possessing a different coefficient of thermal expansion than that of aluminium matrix, appears to be an additional reason for gradual lattice strain development. In addition, a preferred growth of (202) plane along [101] direction towards the final stage of cyclic heat treatment (four cycles) is also revealed. As a result of gradual lattice strain accumulation and grain refinement effects, the hardness of commercially pure aluminium is found to be considerably enhanced (98 HV 10) after 4 cycles of heat treatment as compared to an initial hardness (36 HV 10) in annealed condition.
Gl‐QFOM and Gl‐QGMRES: Two Efficient Algorithms for Quaternion Linear Systems With Multiple Right‐Hand Sides
Authors: Li Tao , Wang Qing‐Wen , Zhang Xin‐Fang 
Published: February 2025

ABSTRACTIn this paper, we propose the global quaternion full orthogonalization (Gl‐QFOM) and global quaternion generalized minimum residual (Gl‐QGMRES) methods, which are built upon global orthogonal and oblique projections onto a quaternion matrix Krylov subspace for solving quaternion linear systems with multiple right‐hand sides. We first develop the global quaternion Arnoldi procedure to preserve the quaternion Hessenberg form during the iterations. We then establish the convergence analysis of the proposed methods and show how to apply them to solve the Sylvester quaternion matrix equation. Numerical examples are provided to illustrate the effectiveness of our methods compared with the traditional Gl‐FOM and Gl‐GMRES iterations for the real representations of the original linear systems.
The Healthcare Integrated Research Database (HIRD) as a Real‐World Data Source for Pharmacoepidemiologic Research
Authors: Barron John J. , Willey Vincent J. , Doherty Brett T. , Tunceli Ozgur , Waltz Craig R. , Grabner Michael , Beachler Daniel C. , Lanes Stephan , Cziraky Mark J. 
Published: February 2025

ABSTRACTBackground and MethodsThe Healthcare Integrated Research Database (HIRD) is a large, comprehensive real‐world data (RWD) source for health‐related research. Demographic and healthcare‐related characteristics of individuals are sourced from routinely updated RWD. The HIRD includes health insurance claims and other health‐related information for individuals enrolled in health insurance plans offered or managed by Elevance Health and has been utilized for research for almost two decades. Individuals in the HIRD reside throughout the United States. Data in the HIRD have been available since January 2006, and are updated monthly.ResultsAs of July 2024, the researchable population of the HIRD included over 91 million individuals with medical benefits, and over 24 million individuals were actively enrolled. The median age of individuals in the HIRD is 36 years (interquartile range [IQR]: 22, 54), and 50% of individuals in the HIRD are female. The median duration of continuous enrollment in the HIRD is 2.0 years (IQR: 0.8, 4.7). For those actively enrolled, the median duration of continuous enrollment is 3.8 years (IQR: 1.7, 8.3). Other important characteristics of the HIRD include the ability to trace data back to their source, support both deterministic and probabilistic linkage with external data sources, and link family members within health plans.ConclusionsThe HIRD has been a trusted resource to generate real‐world evidence for a variety of health‐related research, including regulatory‐required safety studies, comparative effectiveness studies, and health economics and outcomes research.
Etiological factors and clinical outcomes in extracapsular and intracapsular hip fractures among older adults: A gender‐specific analysis
Authors: Lisk Radcliffe , Yeong Keefai , Fluck David , Robin Jonathan , Fry Christopher H. , Han Thang S. 
Published: February 2025

AbstractBackgroundCompared to patients with intracapsular fractures (ICFs), those with extracapsular fractures (ECFs) had worse outcomes. However, most studies of risk factors for these fractures lacked relevant potential reasons, particularly nutritional status, and adjustment for confounding factors. Furthermore, less is known about their effects on clinical outcomes.ObjectiveTo conduct a gender‐specific analysis of community‐dwelling individuals admitted with hip fractures to examine the association of clinical risk factors and health care measures.DesignMonocentric cross‐sectional study.SettingOrthopedic trauma department.ParticipantsA total of 787 women and 318 men of similar mean age (±SD): 83.1 years (±8.6) and 82.5 years (±9.0), respectively.Main Outcome MeasuresMultivariable logistic regression analyzed risk factors including age, gender, dementia, stroke, ischemic heart disease, diabetes, prefracture mobility, alcohol consumption, American Society of Anesthesiologists grades, drug history, and nutrition status for assessing risk factors and outcomes associated with ECFs and ICFs.ResultsCompared to ICFs, for each additional year of age, women had a 3% and men 4% greater association with ECFs. Among women only, ECFs were associated with risk of malnutrition: odds ratio [OR] = 1.70 (95% CI, 1.17–2.48) or malnourishment: OR = 1.93 (95% CI, 1.06–3.52), stroke: OR = 1.85 (95% CI, 1.16–2.97), and diabetes: OR = 1.92 (95% CI, 1.21–3.06). Women with ECFs were less likely to be discharged to their own homes: OR = 0.56 (95% CI, 0.38–0.83); but more likely to be discharged to a rehabilitation unit: OR = 1.81 (95% CI, 1.21–2.71) and readmitted to hospital within 30 days of discharge ≥1 time: OR: 2.39 (95% CI, 1.27–4.50) or ≥2 times: OR = 3.48 (95% CI, 1.05–11.57): they did not differ in discharge to residential or nursing care or in‐hospital mortality. Among men, there were no differences in discharge destinations or readmissions between types of fractures.ConclusionsCompared to ICFs, a greater number of risk factors associated with ECFs were identified more often in women than in men, and ECFs also have greater influences on clinical outcomes in women.
UV‐Curable Polyester Oligomers Containing Triptycene Segments
Authors: Hammer Theodore J. , Pugh Coleen , Soucek Mark D. 
Published: February 2025

ABSTRACTA series of UV‐curable polyesters containing triptycene segments were synthesized via the melt polycondensation of 1,4‐cyclohexanedicarboxylic acid, triptycene‐1,4‐hydroquinone‐bis(2‐hydroxyethyl) ether, and various comonomer diols including 1,6‐hexanediol, neopentyl glycol, and 1,4‐cyclohexanedimethanol. The polyesters were characterized by 1H nuclear magnetic resonance spectroscopy, Fourier‐transform infrared spectroscopy, gel‐permeation chromatography, and differential scanning calorimetry. Thin films were prepared by solvent casting and were cured via exposure to UV‐light at elevated temperature. The crosslinked films were subsequently analyzed by differential scanning calorimetry, dynamic mechanical analysis, Soxhlet extractions, and tensile tests. Most of the samples that contained a high concentration of the triptycene monomer resulted in brittle materials with relatively high moduli and tensile strengths, but poor extensibilities. However, the 1,6‐hexanediol/1,4‐cyclohexanedicarboxylic acid polyester with 30 mol% of triptycene‐1,4‐hydroquinone‐bis(2‐hydroxyethyl) ether exhibited a Tg above room temperature, a relatively high modulus (~1.1 GPa) and tensile strength (~25 MPa), and ductility (144% elongation‐at‐break). These unique properties were attributed to the triptycene monomer, which is capable of threading polymer chains through its V‐shaped cavities to reinforce the polymer network. When these polyesters were formulated into UV‐curable coatings, the coatings displayed excellent impact resistance and substrate adhesion.
Cardiopulmonary Exercise Testing With Simultaneous Echocardiography After Pulmonary Embolism
Authors: Khilzi Karys , Piccari Lucilla , Franco Gerard , Rodó‐Pin Anna , Herranz Anna , Blanco Isabel , Paciocco Giuseppe , Volpiano Lorenzo , Gonzalez Garcia Jose , Diez‐Llaneza Ana , Molina Lluis , Rodríguez Chiaradía Diego A. 
Published: February 2025

ABSTRACTAlthough current guidelines recommend standard cardiopulmonary exercise testing (CPET) to evaluate symptomatic patients after pulmonary embolism (PE), CPET with simultaneous echocardiography could provide relevant information to evaluate right ventricular–pulmonary arterial coupling. The aim of this study was to investigate exercise‐induced changes in echocardiographic variables of RV function or RV– arterial coupling in patients with residual thrombotic defects at 3 months after PE. This retrospective study investigated patients with residual thromboembolic disease on V/Q scintigraphy with persistent symptoms despite adequate anticoagulation after 3 months of acute PE, and resting echocardiography with a low probability of PH. At rest and during exercise, CPET and doppler echocardiography were performed following a standard protocol. Forty‐five patients were included, completing a follow‐up period of at least 24 months. The mean (standard deviation) age was 63 (15) years, and 24 (53%) patients were male. Four patients developed CTEPH after 2 years follow up. Correlation analyses showed that the peak TAPSE was significantly associated with peak workload (r = 0.454, p = 0.003), peak VO2 (r = 0.558, p < 0.001), VE/VECO2 (AT) (r = −0.531, p < 0.001), and oxygen pulse (r = 0.375, p = 0.02). TAPSE/PASP was only slightly associated with peak workload (r = 0.300, p = 0.045). By contrast, the change on TAPSE (from rest to peak) was significantly correlate with peak oxygen uptake (r = 0.491, p = 0.01). Also, reduced VO2 at AT and TAPSE/PASP was seen in patients with CTEPH. CPET with synchronic echocardiography could be a useful tool in early assessment of symptomatic patients with perfusion defects on imaging after 3 months of correctly treated PE.