bluuebunny/crossref_metadata_2025_split huggingface dataset:
Synthesis, Analgesic and Anti‐Inflammatory Evaluation of Some New 3H‐Quinazolin‐4‐one Derivatives
Authors: Alafeefy Ahmed M. , Kadi Adnan A. , El‐Azab Adel S. , Abdel‐Hamide Sami G. , Daba Mohamad‐Hesham Y. 
Published: June 2008

AbstractIn this study, we have synthesized a series of 3H‐quinazolin‐4‐ones in order to obtain new compounds with potential analgesic and anti‐inflammatory activity. The structures of the newly synthesized compounds were confirmed by means of infrared, nuclear magnetic resonance and mass spectroscopy. Some compounds were evaluated for their analgesic and anti‐inflammatory activities by writhing and carrageenan‐induced rat paw edema tests, respectively. In comparison to the standard drug indomethacine, compounds4,6c,12–14,16,18,19, and22induced significant reduction in the writhing response while compounds6c,12,14,16,18, and22produced a good dose‐dependent anti‐inflammatory activity. The best dual analgesic / anti‐inflammatory relative activity was observed with compounds6c,14,16,18, and22.
Calcium as a versatile plant signal transducer under soil water stress
Authors: Hong‐Bo Shao , Li‐Ye Chu , Ming‐An Shao 
Published: June 2008

AbstractThe complexity of calcium profiles observed in plant cells has led to the realization that specific patterns of calcium propagation (now termed calcium signatures) encode specific information and relay it to downstream elements (effectors) for translation into corresponding cellular responses in higher plants. The concept of calcium signatures is now well established and the tight control of the temporal and spatial characteristics of cytosolic calcium alterations is considered to be responsible for the specificity of various cellular responses, in particular to environment‐induced stresses. To date, three major classes of plant calcium sensors responsible for drought‐stress signal transduction during soil water deficit have been identified. Valuable pieces of the calcium signal‐specificity puzzle are being put together and are illustrated here for the calcium‐mediated signal‐transduction cascades that operate in the responses of higher plants to soil environmental deficits. BioEssays 30:634–641, 2008. © 2008 Wiley Periodicals, Inc.
In search of new tractable diatoms for experimental biology
Authors: Chepurnov Victor A. , Mann David G. , von Dassow Peter , Vanormelingen Pieter , Gillard Jeroen , Inzé Dirk , Sabbe Koen , Vyverman Wim 
Published: June 2008

AbstractDiatoms are a species‐rich group of photosynthetic eukaryotes, with enormous ecological significance and great potential for biotechnology. During the last decade, diatoms have begun to be studied intensively using modern molecular techniques and the genomes of four diatoms have been wholly or partially sequenced. Although new insights into the biology and evolution of diatoms are accumulating rapidly due to the availability of reverse genetic tools, the full potential of these molecular biological approaches can only be fully realized if experimental control of sexual crosses becomes firmly established and widely accessible to experimental biologists. Here we discuss the issue of choosing new models for diatom research, by taking into account the broader context of diatom mating systems and the place of sex in relation to the intricate cycle of cell size reduction and restitution that is characteristic of most diatoms. We illustrate the results of our efforts to select and develop experimental systems in diatoms, using species with typical life cycle attributes, which could be used as future model organisms to complement existing ones. BioEssays 30:692–702, 2008. © 2008 Wiley Periodicals, Inc.
Do vertebrate neural crest and cranial placodes have a common evolutionary origin?
Authors: Schlosser Gerhard 
Published: June 2008

AbstractTwo embryonic tissues—the neural crest and the cranial placodes—give rise to most evolutionary novelties of the vertebrate head. These two tissues develop similarly in several respects: they originate from ectoderm at the neural plate border, give rise to migratory cells and develop into multiple cell fates including sensory neurons. These similarities, and the joint appearance of both tissues in the vertebrate lineage, may point to a common evolutionary origin of neural crest and placodes from a specialized population of neural plate border cells. However, a review of the developmental mechanisms underlying the induction, specification, migration and cytodifferentiation of neural crest and placodes reveals fundamental differences between the tissues. Taken together with insights from recent studies in tunicates and amphioxus, this suggests that neural crest and placodes have an independent evolutionary origin and that they evolved from the neural and non‐neural side of the neural plate border, respectively. BioEssays 30:659–672, 2008. © 2008 Wiley Periodicals, Inc.
Enhanced transdermal delivery of a dipeptide by dermaportation
Authors: Namjoshi Sarika , Chen Yan , Edwards Jeffrey , Benson Heather A. E. 
Published: June 2008

AbstractPoor skin permeability and stability limits the application of peptides to the skin. Enhanced skin permeation could offer new therapies for a range of dermatological and cosmetic applications. The aim of this study was to investigate the application of a novel magnetic field enhancement technology to peptide delivery across the skin. Ala‐Trp was used as a model dipeptide. Stability of the dipeptide in a range of conditions and with exposure to skin was determined. Dermaportation‐magnetic field technology increased the in vitro permeability coefficient of Ala‐Trp across human epidermis from 7.7 × 10−4 cm/h with passive diffusion to 1.94 × 10−2 cm/h with Dermaportation. Ala‐Trp was unstable with exposure to human epidermis. Following permeation across the epidermis, a degradation product was detected in the receptor solution with the amount increasing up to 6 h. Given the susceptibility of peptides to degradation in the skin it is essential that they are delivered rapidly across the skin in order to maximize the opportunity for delivery of the native peptide. Dermaportation offers a potential new delivery method for skin delivery of peptides for a range of dermatological and cosmetic applications. © 2008 Wiley Periodicals, Inc. Biopolymers (Pept Sci) 90: 655–662, 2008.This article was originally published online as an accepted preprint. The “Published Online” date corresponds to the preprint version. You can request a copy of the preprint by emailing the Biopolymers editorial office at biopolymers@wiley.com
Theoretical and experimental study of the complexation of valinomycin with ammonium cation
Authors: Dybal Jiří , Ehala Sille , Kašička Václav , Makrlík Emanuel 
Published: June 2008

AbstractThe interactions of valinomycin, macrocyclic depsipeptide antibiotic ionophore, with ammonium cation NH4+ have been investigated. Using quantum mechanical density functional theory (DFT) calculations, the most probable structure of the valinomycin‐NH4+ complex species was predicted. In this complex, the ammonium cation is bound partly by three strong hydrogen bonds to three ester carbonyl oxygen atoms of valinomycin and partly by somewhat weaker hydrogen bonds to the remaining three ester carbonyl groups of the valinomycin ligand. The strength of the valinomycin‐NH4+ complex was evaluated experimentally by capillary affinity electrophoresis. From the dependence of valinomycin effective electrophoretic mobility on the ammonium ion concentration in the background electrolyte, the apparent binding (association, stability) constant (Kb) of the valinomycin‐NH4+ complex in methanol was evaluated as log Kb = 1.52 ± 0.22. © 2008 Wiley Periodicals, Inc. Biopolymers 89: 1055–1060, 2008.This article was originally published online as an accepted preprint. The “Published Online” date corresponds to the preprint version. You can request a copy of the preprint by emailing the Biopolymers editorial office at biopolymers@wiley.com
Genome‐scale model for Clostridium acetobutylicum: Part II. Development of specific proton flux states and numerically determined sub‐systems
Authors: Senger Ryan S. , Papoutsakis Eleftherios T. 
Published: June 2008

AbstractA regulated genome‐scale model for Clostridium acetobutylicum ATCC 824 was developed based on its metabolic network reconstruction. To aid model convergence and limit the number of flux‐vector possible solutions (the size of the phenotypic solution space), modeling strategies were developed to impose a new type of constraint at the endo–exo‐metabolome interface. This constraint is termed the specific proton flux state, and its use enabled accurate prediction of the extracellular medium pH during vegetative growth of batch cultures. The specific proton flux refers to the influx or efflux of free protons (per unit biomass) across the cell membrane. A specific proton flux state encompasses a defined range of specific proton fluxes and includes all metabolic flux distributions resulting in a specific proton flux within this range. Effective simulation of time‐course batch fermentation required the use of independent flux balance solutions from an optimum set of specific proton flux states. Using a real‐coded genetic algorithm to optimize temporal bounds of specific proton flux states, we show that six separate specific proton flux states are required to model vegetative‐growth metabolism and accurately predict the extracellular medium pH. Further, we define the apparent proton flux stoichiometry per weak acids efflux and show that this value decreases from ∼3.5 mol of protons secreted per mole of weak acids at the start of the culture to ∼0 at the end of vegetative growth. Calculations revealed that when specific weak acids production is maximized in vegetative growth, the net proton exchange between the cell and environment occurs primarily through weak acids efflux (apparent proton flux stoichiometry is 1). However, proton efflux through cation channels during the early stages of acidogenesis was found to be significant. We have also developed the concept of numerically determined sub‐systems of genome‐scale metabolic networks here as a sub‐network with a one‐dimensional null space basis set. A numerically determined sub‐system was constructed in the genome‐scale metabolic network to study the flux magnitudes and directions of acetylornithine transaminase, alanine racemase, and D‐alanine transaminase. These results were then used to establish additional constraints for the genome‐scale model. Biotechnol. Bioeng. © 2008 Wiley Periodicals, Inc.
Morphology‐Controlled Assembly of ZnO Nanostructures: A Bioinspired Method and Visible Luminescence
Authors: Begum Gousia , Manorama Sunkara V. , Singh Shashi , Rana Rohit Kumar 
Published: June 2008

AbstractIn a bioinspired methodology, positively charged polypeptides and polyamines directly catalyse ZnO mineralization under “green” conditions of room temperature and neutral pH. The polyamines not only act as mineralizing agents for the formation of ZnO nanoparticles, but also self‐assemble the nanoparticles to form spindle‐like morphologies at these very ambient conditions. Both the directional growth of ZnO and its luminescent property have a pH dependency. At higher pH, the ZnO shape changes to a rodlike morphology that exhibits green photoluminescence with different intensity than that for ZnO spindles.
ChemInform Abstract: Phase Diagram of Mg Insertion into Chevrel Phases, MgxMo6T8 (T: S, Se). Part 3. The Crystal Structure of Triclinic Mg2Mo6Se8.
Authors: Levi E. , Mitelman A. , Isnard O. , Brunelli M. , Aurbach D. 
Published: June 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Structure and Magnetic Properties of Ternary Potassium Lanthanide Oxides KLnO2 (Ln: Y, Nd, Sm—Lu).
Authors: Dong Bin , Doi Yoshihiro , Hinatsu Yukio 
Published: June 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis and Photocatalytic Property of Triple‐Layered Perovskite Compounds, A2Ca4TaxNb6‐xO20 (A = K, H; x = 0, 2, 3, 4, and 6).
Authors: Li Yibin , Wu Jihuai , Huang Yunfang , Huang Miaoliang 
Published: June 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Microwave‐Assisted Aromatic C—O Bond Formation: A Rapid and Efficient Method for the Synthesis of Aryl Ethers.
Authors: Xu Boyan , Xue Jijun , Zhu Jianrong , Li Ying 
Published: June 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Novel Palladium‐on‐Carbon/Diphenyl Sulfide Complex for Chemoselective Hydrogenation: Preparation, Characterization, and Application.
Authors: Mori Akinori , Mizusaki Tomoteru , Kawase Masami , Maegawa Tomohiro , Monguchi Yasunari , Takao Shinobu , Takagi Yukio , Sajiki Hironao 
Published: June 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: An Efficient Protocol of Iridium‐Catalyzed Allylic Substitution Reaction and Its Application to Polymer Synthesis: Complementary Regio‐ and Stereoselective Allylation Polycondensation via Ir and Pd Catalyses.
Authors: Nomura Nobuyoshi , Komiyama Susumu , Kasugai Hiroyuki , Saba Marie 
Published: June 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis of Chloroesters by the Cleavage of Cyclic and Acyclic Ethers Using La(NO3)3×6H2O as a Mild and Efficient Catalyst under Solvent‐Free Conditions.
Authors: Suresh V. , Suryakiran N. , Rajesh K. , Selvam J. Jon Paul , Srinivasulu M. , Venkateswarlu Y. 
Published: June 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: A Cheap Metal for a “Noble” Task: Preparative and Mechanistic Aspects of Cycloisomerization and Cycloaddition Reactions Catalyzed by Low‐Valent Iron Complexes.
Authors: Fuerstner Alois , Majima Keisuke , Martin Ruben , Krause Helga , Kattnig Egmont , Goddard Richard , Lehmann Christian W. 
Published: June 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Utilizing the High Dielectric Constant of Water: Efficient Synthesis of Amino Acid Derivatized Cyclobutenones.
Authors: Li Jun , Han Yongbin , Freedman Teresa B. , Zhu Shifa , Kerwood Deborah J. , Luk Yan‐Yeung 
Published: June 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis of Z‐N‐Alkenylformamides.
Authors: Sanchez Lucina G. , Somanathan Ratnasamy , Hellberg Lars H. , Aguirre Gerardo 
Published: June 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Iron‐Catalyzed C—N Cross‐Coupling of Sulfoximines with Aryl Iodides.
Authors: Correa Arkaitz , Bolm Carsten 
Published: June 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Rationally‐Designed S‐Chiral Bissulfinamides as Highly Enantioselective Organocatalysts for Reduction of Ketimines.
Authors: Pei Dong , Zhang Yu , Wei Siyu , Wang Meng , Sun Jian 
Published: June 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Regioselective Ring‐Opening of Epoxides with Amines Using Zn(ClO4)2—Al2O3 as a Heterogeneous and Recyclable Catalyst.
Authors: Maheswara Muchchintala , Rao Kummari Subba Venkata , Do Jung Yun 
Published: June 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Nitrile Biotransformations for the Synthesis of Enantiomerically Enriched β2‐, and β3‐Hydroxy and ‐Alkoxy Acids and Amides, a Dramatic O‐Substituent Effect of the Substrates on Enantioselectivity.
Authors: Ma Da‐You , Wang De‐Xian , Pan Jie , Huang Zhi‐Tang , Wang Mei‐Xiang 
Published: June 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Microwave‐Induced Solvent‐Free Synthesis of β‐Keto Esters Using Montmorillonite KSF and K10 Clays as Efficient and Recyclable Heterogeneous Solid Acids.
Authors: Marvi Omid , Habibi Davood 
Published: June 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: First Example of Diels—Alder Reaction of 4‐(1‐Ethenylsubstituted)‐3‐methylisoxazoles with Acetylenedicarboxylates.
Authors: Chimichi Stefano , Cosimelli Barbara , Boccalini Marco , Matteucci Alessandra , Messaoudi Abdelatif 
Published: June 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Aerobic Ligand‐Free Suzuki Coupling Reaction of Aryl Chlorides Catalyzed by in situ Generated Palladium Nanoparticles at Room Temperature.
Authors: Han Wei , Liu Chun , Jin Zilin 
Published: June 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis of Tri(indolyl)methanes Mediated by Acidic Ionic Liquid.
Authors: Gu Da‐Gong , Ji Shun‐Jun 
Published: June 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Sustainable Conjugate Addition of Indoles Catalyzed by Acidic Ionic Liquid Immobilized on Silica.
Authors: Hagiwara Hisahiro , Sekifuji Masayoshi , Hoshi Takashi , Suzuki Toshio , Quanxi Bao , Qiao Kun , Yokoyama Chiaki 
Published: June 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: C—H Functionalization/C—N Bond Formation: Copper‐Catalyzed Synthesis of Benzimidazoles from Amidines.
Authors: Brasche Gordon , Buchwald Stephen L. 
Published: June 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Exo Selective Cycloaddition Reactions of α‐Hydroxy Cyclic Nitronates to Allylic Alcohols in the Presence of Magnesium Ions Leading to Isoxazolidines and Isoxazolines.
Authors: Nishiuchi Masaki , Sato Hiroyasu , Umemoto Nao , Murakami Sayoko 
Published: June 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Convenient Preparation of 2,7,8‐Trimethyl‐6‐hydroxychroman‐2‐carboxylic Acid (γ‐Trolox).
Authors: Hyatt John A. 
Published: June 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Reaction of 2‐Alkylthiopyridinium Salts with Active Methylene Compounds.
Authors: Hoshino Masato , Taguchi Tsuyoshi , Nakano Hiroto , Tomisawa Hiroshi , Matsuzaki Hisao , Fujita Reiko 
Published: June 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.