bluuebunny/crossref_metadata_2025_split huggingface dataset:
INNOVATIONS IN BUSINESS MODELS THROUGH STRATEGIC ANALYTICS AND MANAGEMENT: CONCEPTUAL EXPLORATION FOR SUSTAINABLE GROWTH
Authors: Nneka Adaobi Ochuba  , Favour Oluwadamilare Usman  , Olukunle Oladipupo Amoo  , Enyinaya Stefano Okafor  , Olatunji Akinrinola  
Published: March 2024

In today's rapidly evolving business landscape, the integration of strategic analytics and management practices has become increasingly crucial for organizations seeking sustainable growth and competitive advantage. This paper aims to explore the concept of leveraging strategic analytics within business models to drive innovation and foster sustainable growth. The modern business environment is characterized by unprecedented levels of complexity, volatility, and uncertainty. Globalization, technological advancements, and shifting consumer preferences have disrupted traditional business models, compelling organizations to adapt or risk obsolescence. In this context, strategic analytics emerges as a powerful tool for organizations to navigate uncertainty, mitigate risks, and capitalize on emerging opportunities. Strategic analytics involves the systematic collection, processing, and analysis of data to inform decision-making processes and drive strategic initiatives. By leveraging advanced analytical techniques such as predictive modeling, machine learning, and data mining, organizations can gain actionable insights into various aspects of their operations, including customer behavior, market trends, and competitive dynamics. By leveraging advanced analytical techniques, organizations can gain a deeper understanding of customer needs, optimize internal processes, and anticipate changes in the competitive landscape. This enables organizations to drive innovation, foster sustainable growth, and create value for customers, shareholders, and society as a whole. Through a conceptual exploration, we examine the fundamental principles, challenges, and opportunities associated with integrating strategic analytics into various facets of business models. Drawing upon theoretical frameworks and empirical evidence, this paper elucidates the transformative potential of strategic analytics in reshaping traditional business models and creating new avenues for value creation. Furthermore, we discuss the implications for managers, policymakers, and researchers, highlighting the imperative of embracing strategic analytics as a cornerstone for driving organizational success in the digital age.
Keywords: Business, Model Innovation, Sustainable Growth, Management, Strategic Analytics.
Holistic approach of Talent Management for a successful Succession Planning
Authors: Dr. Satuluri Padma Mukesh Mihir, 
Published: March 2024

Preparing ourselves for future volatile economic environment is a challenge. Every Organization needs to develop a succession plan for taking up the roles and responsibility by the next generation leaders. Indian Public Sectors Units (PSUs) often find themselves in a challenging situation while positioning suitable manpower for the key leadership positions in the changing market situation. They adopt several Management Practices to develop future leaders within the organization, as it is more preferable to develop a Talent Pool in-house, rather than acquiring it from outside. Based on various studies in the past, relationship between Succession planning and Talent Management is well established. Yet, the impact of Performance Management in particular, needs to be specifically addressed, critically analyzed and reviewed in depth in line with acquiring, developing and retaining the talent for a successful Succession Planning.
Problem statement - how does Performance Management System impact on Succession Planning? what is the relevance in integrating these two and how does it contribute to organizational sustainability? what are the Talent Management processes that support successful Succession Planning?
The study involves a sample of Indian PSUs from various sectors. A mixed method approach for data analysis is preferred. Document analysis involves review of Policy/guidelines, Procedures and Reports related to Human Resource Development (HRD); whereas feedback on perception of employees were collected through interactions with key stakeholders and analyzed using thematic analysis to identify linkage between Performance Management and Succession Planning.
The study suggests the holistic approach towards Talent Management and its best practices for a successful Succession Planning. It recommends to identify and develop individuals in-house, for the critical and key leadership roles thus achieving organizational sustainability.
Experimental Investigations and Qualification of Innovative Flow Sensors in the 1000 K SOLTEC-2 Sodium Loop
Authors: Onea Alexandru , Krauter Nico , Hering Wolfgang , Lenk Stephan , Ruck Sebastian , Stieglitz Robert , Gerbeth Gunter 
Published: March 2024

Liquid metals, such as sodium, have been already successfully used as heat transfer fluids (HTF) in concentrating solar power (CSP) plants up to ~550 °C. Even higher temperatures can be achieved and are envisioned for future CSP plants. The lack of measuring flow rate devices at high temperatures for liquid metals motivated this study. The present paper presents the experimental mock-up and the experimental results obtained with the SOLTEC-2 facility for two test flow sensors, one innovative eddy current flow sensor (ECFM) developed at HZDR, Germany and a built-in permanent magnet fly-wheel sensor for runs up to a sodium temperature of 700 °C. The signals of the sensors are compared also against the power level of the sodium pump.
PENGARUH FORMULASI SANTAN DAN LABU KUNING (Cucurbita moschata) TERHADAP SIFAT FISIK DAN KIMIA ES KRIM
Authors: Selvie Mahrita  , Evi Faridawaty  , Christian Feri  
Published: March 2024

Penelitian ini bertujuan untuk mencari pengaruh formulasi dari santan dan labu kuning terhadap sifat fisik dan kimia es krim agar mendapatkan formulasi terbaik. Penelitian ini menggunakan Rancangan Acak Kelompok (RAK) yang terdiri dari satu faktor, yaitu campuran formulasi antara santan dan labu kuning. Penelitian ini menggunakan 4 perlakuan formulasi, yaitu : A0 (50% santan dan 50% labu kuning), A1 (40% santan dan 60% labu kuning), A2 (30% santan dan 70% labu kuning) dan A3 (20% santan dan 80% labu kuning). Pada penelitian ini terdapat 4 perlakuan dan 5 kali ulangan, sehingga terdapat 20 sampel satuan percobaan. Parameter yang di uji meliputi daya leleh (menit), kadar protein (%), kadar air (%), kadar lemak (%), total padatan (%) dan uji organoleptik. Berdasarkan hasil penelitian, formulasi santan dan labu kuning berpengaruh nyata terhadap daya leleh (menit), kadar protein (%), kadar air (%), kadar lemak (%), total padatan (%) dan uji organoleptik berdasarkan parameter warna dan tekstur, tetapi tidak berpengaruh nyata terhadap rasa dan aroma. Perlakuan A0 (50% santan dan 50% labu kuning) adalah pelakuan terbaik, karena kadar lemak, kadar air dan total padatan memenuhi Standar Nasional Indonesia (SNI) produk es krim
The Application of Artificial Intelligence in the Research and Development of Traditional Chinese Medicine
Authors: Ke Zhipeng , Liu Minxuan , Liu Jing , Su Zhenzhen , Li Lu , Qian Mengyu , Zhang Xinzhuang , Cao Liang , Wang Tuanjie , Wang Zhenzhong , Xiao Wei 
Published: March 2024

Review
The Application of Artificial Intelligence in the Research and Development of Traditional Chinese Medicine

Zhipeng Ke 1,2, Minxuan Liu 1,2,3, Jing Liu 1,2, Zhenzhen Su 1,2, Lu Li 1,2, Mengyu Qian 1,2, Xinzhuang Zhang 1,2, Tuanjie Wang 1,2, Liang Cao 1,2, Zhenzhong Wang 1,2, and Wei Xiao 1,2, *

1 National Key Laboratory on Technologies for Chinese Medicine Pharmaceutical Process Control and Intelligent Manufacture, Lianyungang 222106, China
2 Jiangsu Kanion Pharmaceutical Co., Ltd, Lianyungang 222104, China
3 ‍School of Pharmacy, Nanjing University of Chinese Medicine, Nanjing 210009, China
* Correspondence: xw_kanion@163.com

Received: 4 September 2023
Accepted: 4 November 2023
Published: 6 March 2024

Abstract: With the accumulation of data in the pharmaceutical industry and the development of artificial intelligence technology, various artificial intelligence methods have been successfully employed in the drug discovery process. The integration of artificial intelligence in Traditional Chinese medicine has also gained momentum, encompassing quality control of Chinese patent medicines, prescriptions optimization, discovery of effective substances, and prediction of side effects. However, artificial intelligence also faces challenges and limitations in Traditional Chinese medicine development, such as data scarcity and complexity, lack of interdisciplinary professionals, black-box models, etc. Therefore, more research and collaboration are needed to address these issues and explore the best ways to integrate artificial intelligence and Traditional Chinese medicine to improve human health.
Mkk7 Protects Against Cardiac Dysfunction in Heart Failure with Preserved Ejection Fraction
Authors: Azam Tayyiba , Zhang Hongyuan , Hille Susanne , Müller Oliver J. , Cartwright Elizabeth J. , Wang Xin 
Published: March 2024

Article
Mkk7 Protects Against Cardiac Dysfunction in Heart Failure with Preserved Ejection Fraction

Tayyiba Azam 1, * , Hongyuan Zhang 1, Susanne S. Hille 2, Elizabeth J. Cartwright 1, Oliver J. Müller 2, and Xin Wang 1, *

1 Faculty of Biology, Medicine, and Health, University of Manchester, Oxford Road, M13 9PT, Manchester, UK
2 Department of Internal Medicine III, University of Kiel, Germany; German Centre for Cardiovascular Research (DZHK), 24105 Partner Site Hamburg/Kiel/Lübeck, Germany
* Correspondence: xin.wang@manchester.ac.uk (Xin Wang); tayyiba.azam@manchester.ac.uk (Tayyiba Azam)

Received: 12 June 2023
Accepted: 25 September 2023
Published: 6 March 2024

Abstract: Shifts in epidemiological patterns foretell a rapid increase in the number of patients with heart failure (HF) globally, representing a significant health and economic burden. Heart failure with preserved ejection (HFpEF) is now considered the prevailing subtype of HF, with no effective treatment available to combat this syndrome. Previous studies have highlighted the cardioprotective role of MKK7 during cardiac pathology, however, no extensive research has been performed to examine MKK7 in the context of HFpEF. This study aimed to address this shortcoming by using adeno-associated virus (AAV) 9 to overexpress MKK7 in the two-hit clinically relevant HFpEF mouse model. We report that cardiomyocyte-specific overexpression of MKK7 improved the HFpEF phenotype in mice, by impeding cardiac diastolic dysfunction and myocardial fibrosis. Mechanistically, it was found that MKK7 ameliorated ER stress by maintaining IRE1-XBP1 signalling and blunted CHOP increase in the myocardium. To summarise, MKK7 overexpression holds the ability to protect the myocardium from HFpEF associated pathologies.
Kontribusi Kualitas Kehidupan Kerja terhadap Keterlekatan Karyawan pada Generasi Z
Authors: Nurhalizah Siti Supriyadi , Mulyani Indah 
Published: March 2024

Keterlekatan karyawan adalah salah satu kunci keberhasilan untuk mencapai visi dan misi perusahaan secara optimal. Keterlekatan karyawan menunjang dalam seseorang engaged dalam bekerja, maka karyawan akan senang dan puas terhadap pekerjaan. Dapat dikatakan bahwa rasa senang dan puas seorang karyawan dapat dilihat bagaimana perusahaan dapat memberikan kualitas kehidupan kerja terhadap karyawannya. Penelitian ini bertujuan untuk melihat kontribusi kualitas kehidupan kerja terhadap keterlekatan karyawan pada generasi Z. Penelitian ini menggunakan pendekatan kuantitatif. Alat ukur yang digunakan yaitu Development and application of a new measure of employee engagement: the ISA Engagement Scale untuk mengukur keterlekatan karyawan. Work-related quality of life (WRQoL) scale untuk mengukur kualitas kehidupan kerja. Pengujian hipotesis dilakukan dengan analisis regresi sederhana. Hasil penelitian menunjukkan terdapat kontribusi kualitas kehidupan kerja terhadap keterlekatan karyawan pada generasi Z. Dimana hal tersebut menunjukkan bahwa semakin tinggi kualitas kehidupan kerja, maka semakin tinggi keterlekatan karyawan pada generasi Z. Penelitian ini dapat menjadi referensi pembuatan modul untuk jurusan psikologi, serta pihak lainnya untuk meningkatkan keterlekatan karyawan dengan memperhatikan kualitas kehidupan kerja.
Pengaruh Fasilitas Wisata terhadap Minat Berkunjung Kembali Wisatawan di Kebun Raya Bogor
Authors: Winanto Eugenius Figo , Djunaid Ika Suryono 
Published: March 2024

Penelitian ini dilatarbelakangi oleh fasilitas wisata yang menjadi tujuan utama wisatawan untuk mau melakukan kunjungan kembali di Kebun Raya Bogor. Fasilita wisata memudahkan wisatawan untuk melakukan berbagai kegiatan wisata di Kebun Raya Bogor. Adanya fasilitas wisata juga membantu mendongkrang minat berkunjung wisatawan hingga melakukan kunjungan kembali. Metode analisis yang digunakan pada penelitian ini menggunakan metode pendekatan kualitatif dengan data premier menggunakan kuesioner dalam memperoleh sumber data untuk hasil penelitian. Metode analisis yang digunakan adalah uji validitas dan reliabilitas, uji asumsi klasik dan uji hipotesis. Hasil dari penelitian ini menunjukkan bahwa adanya pengaruh positif fasilitas wisata terhadap minat berkunjung kembali secara signifikan pada Kebun Raya Bogor sebesar 58.1% terhadap minat berkunjung kembali. Sedangkan sisa 41.9% lainnya dipengaruhi hal luar dari variabel yang diuji dalam penelitian ini. Kesimpulan dalam penelitian ini pengaruh variabel fasilitas wisata terhadap minat berkunjung kembali dinilai cukup signifikan. Saran Dari segi fasilitas, pihak pengelola perlu untuk lebih rajin maintenace fasilitas transpotasi yang berada diarea Kebun Raya Bogor supaya bisa menambah kenyamanan wisatawan. Menambah atau membuka ruangan kesehatan atau P3K. Bisa memperbanyak tempat untuk berteduh karena seperti yang kita ketahui bahwa Bogor merupakan kota hujan yang bisa sewaktu waktu terjadi hujan sehingga wisatawan tidak bingung untuk mencari tempat berteduh.
Pengembangan LKS berbasis CTL untuk Meningkatkan Hasil Belajar Siswa Kelas III SD
Authors: Zurro Aisatuz , Dewi Anggralita Sandra , Mubarok M. Khusni 
Published: March 2024

Penelitian ini bertujuan untuk mengetahui kelayakan LKS berbasis CTL serta hasil pembelajaran siswa sesudah menggunakan LKS berbasis CTL. Jenis penelitian ini Research and Development/RND. Subjek penelitian ini yaitu siswa kelas III-A yang terdiri dari 15 perempuan serta 15 laki-laki. Instrumen penelitian yang digunakan yaitu 1) uji validasi ahli materi, media, dan soal untuk mengetahui kelayakan sebuah media 2) uji realibilitas&validitas tes untuk mengamati valid atau tidaknya soal tes 3) uji N-Gain untuk mengetahui hasil pembelajaran yang telah dicapai siswa. Hasil dari validasi ahli media memperoleh skor 90% dan dinyatakan sangat setuju, sedangkan hasil dari validasi ahli materi memperoleh skor 88,5% layak dan sangat setuju. Perolehan validasi soal mendapati 91,4% dengan kriteria sangat setuju dan layak digunakan siswa. Hasil uji validitas dan reliabel dengan nilai alpha cronbach >0,5 yaitu 0,700 pada soal uraian dan 0,738 pada soal pilihan ganda. Hasil dari uji N-gain mengalami peningkatan dan nilai rata-rata pretest 64,66 dan postest 81,40 sehingga hasil nilai N-Gain 0,47 dengan kriteria sedang. Dapat disimpulkan bahwa LKS berbasis CTL layak digunakan pada proses pembelajaran serta dapat meningkatkan hasil pembelajaran siswa kelas III SD.
Are You Our Sisters? Resistance, Belonging, and Recognition in Israeli Reform Jewish Female Converts
Authors: Libel-Hass Einat , Ben-Lulu Elazar 
Published: March 2024

The religious conversion process is a significant expression of an individual’s intention to gain a new religious identity and be included in a particular religious community. Those who wish to join the Jewish people undergo giyur (conversion), which includes observing rituals and religious practices. While previous research on Jewish conversions in Israel focused on the experiences of persons who converted under Orthodox auspices, this study analyzes the experiences of female immigrants from the former Soviet Union (FSU) and the Philippines who chose to convert through the Reform Movement in Israel. Based on qualitative research, we discovered that the non-Orthodox process, which is based on liberal values, not only grants converts under the aegis of Reform entry to the Jewish people, but promotes their affiliation with the Reform Movement and advances their acculturation into Jewish Israeli society. Their choice is a political decision, an act of resistance against an Orthodox Israeli religious monopoly, and an expression of spiritual motivations. The converts become social agents who strengthen the Reform Movement’s socio-political position in Israel, where it struggles against discrimination. Furthermore, since most converts are women, new intersections between religion, gender, and nationality are exposed.
Manajemen Marketing Dan Perilaku Konsumen Di UIN Sunan Ampel Surabaya
Authors: Zahrohu Maulida , Filla Anggun Dwi Saputri Nurma , Indri Ikhtiarini Febriani , Ilham Moh 
Published: March 2024

Abstrak
Lembaga pendidikan harus bisa memperhatikan berbagai sudutpersaingan yang ada untuk mempertahankan eksistensinya dan menarik minat mahasiswa dalam meyakinkan pilihannyaterhadap lembaga pendidikan yang akan dipilih. Penelitian inimenggunakan teknik penelitian deskriptif kualitatif yang berdasarkan pendekatan studi pustaka serta studi lapangan. Analisis data dilakukan dengan melakukan redaksi data dan ekstraksi data. Penelitian ini mengeksplorasi pentingnyaintegrasi antara prinsip-prinsip manajemen marketing yang berbasis nilai-nilai Islam dengan pemahaman yang mendalamtentang perilaku konsumen dalam pendidikan Islam untukmemberikan layanan pendidikan yang berkualitas dan sesuaidengan nilai-nilai agama. Dari hasil penelitian ini adalah, UIN Sunan Ampel Surabaya (UINSA) memiliki manajemenmarketing yang cukup baik mulai dari pemanfaatan sosial media yang dimilikinya serta berbagai program international maupunnon international. UINSA memberikan fasilitas yang memadaidan program-program yang berkualitas sehingga menarikkonsumen untuk kuliah di UINSA. Manajemen marketing yang diterapkan dengan baik berdampak juga pada reputasi UINSA itu sendiri, sehingga UINSA bisa menjadi salah satu kampusterbaik di Surabaya yang bersaing dengan PTN yang ada di Surabaya.
Kata kunci: Pendidikan, manajemen, perilaku konsumen
Experiência exitosa acerca da construção do saber para uma assistência de enfermagem à mulher climatérica
Authors: Rodrigues Juliana Nascimento de Barros , Vieira Bianca Dargam Gomes , Alves Valdecyr Herdy , Calandrini Tatiana do Socorro dos Santos , Santos Marcia Vieira dos , Barbosa Siomara Correia de Holanda , Silva Amanda Mirlla Santos da , Pereira Neusa Aparecida Mendes 
Published: March 2024

Objetivo: descrever a experiência da realização de um evento on-line acerca da assistência de enfermagem à mulher climatérica realizado pelo Grupo de Pesquisa Maternidade: Saúde das Mulheres e Crianças, do Departamento de Enfermagem Materno-Infantil e Psiquiátrico, da Escola de Enfermagem Aurora de Afonso Costa/Universidade Federal Fluminense, Eixo de Ginecologia, Obstetrícia, Saúde Sexual e Reprodutiva. Método: trata-se de um relato de experiência a partir de um evento via Google Meet, realizado no dia 12 de julho de 2023, intitulado: Consulta de enfermagem ginecológica com foco na assistência à mulher climatérica: possibilidades e limites, disponibilizado para profissionais da saúde. O tema foi escolhido com base na “percepção” de trabalhar as questões referentes ao climatério na perspectiva de um olhar ampliado, uma abordagem integral e uma assistência de qualidade à mulher durante essa fase da vida, a partir da consulta de enfermagem à mulher na Atenção Primária. A plataforma Menti.com foi utilizada para aumentar a interação dos participantes por meio da construção de uma nuvem de palavras a partir da pergunta “O que você entende por climatério?” Resultados: foram registradas 188 inscrições, sendo 29% de alunos de graduação e 71% de profissionais de enfermagem, provenientes de todas as regiões do Brasil, o que evidencia interesse e engajamento dos profissionais de saúde e pesquisadores no tema da assistência à mulher climatérica. Conclusão: o evento científico on-line demonstrou a importância da assistência de enfermagem à mulher climatérica, reconhecendo tanto as possibilidades quanto os limites inerentes a essa prática. Ficou evidente a relevância desse tema, considerando o impacto que o climatério pode ter na qualidade de vida das mulheres e a necessidade de uma abordagem holística e individualizada nessa fase da vida, baseada nas melhores evidências científicas. Durante o evento evidenciou-se a importância de realização de novos estudos científicos com essa temática, que possibilitem o compartilhamento de conhecimentos, experiências e práticas bem-sucedidas na assistência à mulher climatérica. A troca de informações entre profissionais e pesquisadores contribui para o avanço da ciência da enfermagem, promovendo a melhoria contínua da qualidade dos cuidados oferecidos.
Electrochemical profiling of natural furanocoumarins: DNA interaction dynamics of oxypeucedanin and prantschimgin
Authors: Kaya Hüseyin Oğuzhan , Albayrak Gokay , Isbilir Hasan , Kurul Fatma , Baykan Sura , Hartati Yeni Wahyuni , Topkaya Seda Nur 
Published: March 2024

Background and purpose: In this study, we present an electrochemical sensor for the detection of oxypeucedanin (Oxyp) and prantschimgin (Pra), two natural furanocoumarin derivatives. The determination of the effects of these molecules on DNA is important to be potential drug candidates. Our research focused on exploring the electrochemical behaviour of these compounds and their interaction with DNA. Experimental approach: The electrochemical properties of Oxyp and Pra were systematically analyzed by evaluating their oxidation currents. Changes in the oxidation currents and peak potentials of guanine bases were monitored before and after interaction in the solution phase and at the electrode surface. Key results: The limit of detection (LOD) and limit of quantitation (LOQ) for Oxyp were determined to be 1.3 and 4.3 µg/mL, respectively. For Pra, the LOD and LOQ were found to be 20 and 68 µg/mL, respectively. Stability studies demonstrated that the Oxyp solution retained its oxidation capacity for over a month, whereas the Pra solution retained its oxidation capacity for nearly 120 min. Our findings suggest that Oxyp interacts with dsDNA, potentially through electrostatic interactions, showing promise as a potential drug candidate targeting DNA. On the other hand, the interaction of Pra with dsDNA requires further exploration to fully understand its mode of action. Conclusion: The electrochemical sensor developed in this study provides a reliable and efficient method for detecting and analysing the interaction of these natural compounds with dsDNA. Our research contributes to advancing the understanding of the interaction between natural furanocoumarins and dsDNA, laying the groundwork for the design and development of novel and effective DNA-targeted drugs.