bluuebunny/crossref_metadata_2025_split huggingface dataset:
ChemInform Abstract: Crystal Engineering with Urea and Thiourea Hydrogen‐Bonding Groups
Authors: Custelcean Radu 
Published: April 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: The Next Generation of Shape‐Persistent Zeolite Analogues: Covalent Organic Frameworks
Authors: Mastalerz Michael 
Published: April 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Hole Control in Microporous Polymers
Authors: Weder Christoph 
Published: April 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: The Larger Acenes: Versatile Organic Semiconductors
Authors: Anthony John E. 
Published: April 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Alignment by the Convective and Vortex Flow of Achiral Self‐Assembled Fibers Induces Strong Circular Dichroism Effects
Authors: Spada Gian Piero 
Published: April 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Dynamic Combinatorial Chemistry: On the Road to Fulfilling the Promise.
Authors: Ladame Sylvain 
Published: April 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Chemistry of the Anionically Activated Aromatic ‐CF3 Group
Authors: Kiselyov Alexander S. 
Published: April 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Fluorous Carboxylates as Useful Metal Ligands for Catalyst Products Recovery: Procedures and Sensing
Authors: El Bakkari Mounir , Vincent Jean‐Marc 
Published: April 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: A Practical Synthesis of a Key Chiral Drug Intermediate via Asymmetric Organocatalysis
Authors: Seki Masahiko 
Published: April 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Imidoyl Radicals in Organic Synthesis
Authors: Minozzi Matteo , Nanni Daniele , Spagnolo Piero 
Published: April 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Deoximation of Keto‐ and Aldoximes to Carbonyl Compounds
Authors: Sahu Sandhyamayee , Sahu Sagarika , Patel Sabita , Dash Sukalyan , Mishra Bijay K. 
Published: April 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: An Organocatalytic Regioselective Acylation of Carbohydrates: Toward the Development of Intelligent Catalysts
Authors: Kawabata Takeo 
Published: April 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Bifunctional Organocatalysts for Enantioselective aza‐Morita—Baylis—Hillman (aza‐MBH) Reactions
Authors: Takizawa Shinobu , Matsui Katsuya , Sasai Hiroaki 
Published: April 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Alternating Copolymerization of Polar Olefins with Carbon Monoxide
Authors: Nozaki Kyoko 
Published: April 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Designer Aminoglycosides: The Race to Develop Improved Antibiotics and Compounds for the Treatment of Human Genetic Diseases.
Authors: Hainrichson Mariana , Nudelman Igor , Baasov Timor 
Published: April 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Chemistry and Biology of the Aeruginosin Family of Serine Protease Inhibitors
Authors: Ersmark Karolina , Del Valle Juan R. , Hanessian Stephen 
Published: April 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Composites of Intrinsically Conducting Polymers as Sensing Nanomaterials
Authors: Hatchett David W. , Josowicz Mira 
Published: April 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: 1H CRAMPS NMR of Polypeptides in the Solid State
Authors: Shoji Akira 
Published: April 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Rapid Normalization of a Highly Thickened Pericardium by Chemotherapy in a Patient with T‐cell Acute Lymphoblastic Lymphoma
Authors: Kilicaslan Fethi , Akyol Erikci Alev , Kirilmaz Ata , Ulusoy Eralp , Cebeci Bekir , Ozturk Ahmet , Dincturk Mehmet 
Published: April 2008

AbstractThe most common tumor that affects the pericardium is malign lymphoma. T‐cell lymphoblastic lymphoma (TLL) is a rare type of malign lymphomas. In this manuscript, we are reporting a patient with TLL with pericardial involvement diagnosed incidentally during the evaluation of pleural effusion. Echocardiographic examination showed thickened pericardium and pericardial effusion. The pericardial thickness was found to be 13 mm by computerized tomography and confirmed by echocardiography. The patient had systemic chemotherapy for TLL. On day 30 of chemotherapy, computerized tomography of the thorax and echocardiographic examination revealed normal pericardial thickness and minimal pericardial effusion. Copyright © 2008 Wiley Periodicals, Inc.
Localization of βv tubulin in the cochlea and cultured cells with a novel monoclonal antibody
Authors: Banerjee Asok , Jensen‐Smith Heather , Lazzell Anna , Prasad Veena , Elguezabal Gerardo , Hallworth Richard , Ludueña Richard F. 
Published: April 2008

AbstractTubulin, the dimeric structural protein of microtubules, is a heterodimer of α and β subunits; both α and β exist as numerous isotypes encoded by different genes. In vertebrates the sequence differences among the βI, βII, βIII, βIV and βV isotypes are highly conserved in evolution, implying that the isotypes may have functional significance. Isotype‐specific monoclonal antibodies have been useful in determining the cellular and sub‐cellular distributions and possible functions of the βI, βII, βIII, and βIV isotypes; however, little is known about the βV isotype. We here report the creation and purification of a monoclonal antibody (SHM.12G11) specific for βV. The antibody was designed to be specific for the C‐terminal sequence EEEINE, which is unique to rodent and chicken βV. The antibody was found to bind specifically to the C‐terminal peptide EEEINE, and does not cross‐react with the carboxy‐termini of either α‐tubulin or the other β‐tubulin isotypes. However, the antibody also binds to the peptide EEEVNE, but not to the peptide EEEIDG, corresponding respectively to the C‐terminal peptides of bovine and human βV. Immunofluorescence analysis indicates that βV is found in microtubules of both the interphase network and the mitotic spindle. In gerbils, βV also occurs in the cochlea where it is found largely in the specialized cells that are unique in containing bundled microtubules with 15 protofilaments. Cell Motil. Cytoskeleton 2008. © 2008 Wiley‐Liss, Inc.
Hearing in a diurnal, mute butterfly, Morpho peleides (Papilionoidea, Nymphalidae)
Authors: Lane Karla A. , Lucas Kathleen M. , Yack Jayne E. 
Published: April 2008

AbstractMorpho peleides with extracellular auditory nerve recording in background. J. Comp. Neurol. 508:677–686, 2008. © 2008 Wiley‐Liss, Inc.
A novel method for the detection of viable human pancreatic beta cells by flow cytometry using fluorophores that selectively detect labile zinc, mitochondrial membrane potential and protein thiols
Authors: Jayaraman Sundararajan 
Published: April 2008

AbstractImprovement over current methods of beta cell viability assessment is highly warranted in order to efficiently predict the viability and function of beta cells prior to transplantation into type 1 diabetes patients. Dispersed human islet cells were stained with the cell‐permeable zinc‐selective dye, FluoZin‐3‐AM, along with the mitochondrial membrane potential indicator [(tetramethylrhodamine ethylester (TMRE)] and the thiol‐binding dye, monochlorobimane (mBcl), and analyzed by flow cytometry. Islets were subjected to various experimental conditions to validate the usefulness of this method to accurately determine the viability and function of beta cells. Staining with FluoZin‐3 revealed the presence of higher amounts of chelatable zinc ions in beta cells than in lymphoid cells and fibroblasts. An intracellular zinc chelator competitively inhibited the binding of FluoZin‐3 to zinc ions. Mitochondrial depolarization or oxidative stress minimally affected the binding of mBcl and FluoZin‐3, respectively, to thiols and zinc ions. The combination of FluoZin‐3, TMRE, and mBcl was sufficient and necessary for the determination of the viability and function of beta cells. The data demonstrate the usefulness of the zinc‐specific dye and the indicators of mitochondrial function and thiol levels, to accurately estimate the beta cell viability and function. This novel flow cytometry method has implications for islet transplantation in type 1 diabetes patients. © 2008 International Society for Analytical Cytology.
Degenerate TCR recognition and dual DR2 restriction of autoreactive T cells: Implications for the initiation of the autoimmune response in multiple sclerosis
Authors: Zhang Xin , Tang Yunan , Sujkowska Danuta , Wang Jinzhao , Ramgolam Vinod , Sospedra Mireia , Adams Jeremy , Martin Roland , Pinilla Clemencia , Markovic‐Plese Silva 
Published: April 2008

AbstractTCR degeneracy may facilitate self‐reactive T cell activation and the initiation of an autoimmune response in multiple sclerosis (MS). MHC class II alleles of the DR2 haplotype DR2a (DRB5*0101) and DR2b (DRB1*1501) are associated with an increased risk for MS in Caucasian populations. In order to selectively expand and characterize T cells with a high degree of TCR degeneracy that recognize peptides in the context of disease‐associated DR2 alleles, we developed DR2‐anchored peptide mixtures (APM). We report here that DR2‐APM have a high stimulatory potency and can selectively expand T cells with a degenerate TCR (TCRdeg). Due to the low concentration of individual peptides in the mixtures, T cell clones’ proliferative response to DR2‐APM implies that multiple peptides stimulate the TCR, which is a characteristic of TCRdeg. The frequency of DR2‐APM‐reactive T cells is significantly higher in MS patients than in healthy controls, suggesting that they may play a role in the development of the autoimmune response in MS. DR2‐APM‐reactive cells have a dual DR2 restriction: they recognize DR2‐APM in the context of both DR2a and DR2b molecules. The DR2‐APM‐reactive cells’ IL‐17 secretion, together with cross‐reactivity against myelin peptides, may contribute to their role in the development of autoimmune response in MS.Supporting Information for this article is available at http://www.wiley‐vch.de/contents/jc_2040/2008/37519_s.pdfSee accompanying article: http://dx.doi.org/10.1002/eji200838371
Continuous generation of colitogenic CD4+ T cells in persistent colitis
Authors: Tomita Takayuki , Kanai Takanori , Fujii Toshimitsu , Nemoto Yasuhiro , Okamoto Ryuichi , Tsuchiya Kiichiro , Totsuka Teruji , Sakamoto Naoya , Watanabe Mamoru 
Published: April 2008

AbstractInflammatory bowel diseases take chronic courses due to the expansion of colitogenic CD4+ cells. However, it is unclear whether the persistent disease is driven by continuous reactivation of colitogenic memory CD4+ cells to generate effector CD4+ cells or by continuous generation of effector CD4+ cells from naïve cells. To clarify this issue, we performed a series of sequential adoptive transfers of Ly5.2+ and Ly5.1+ CD4+CD45RBhigh cells into RAG‐2–/– mice at different time points. We show here that the secondarily transferred CD4+CD45RBhigh cells can be converted to CD4+CD44highCD62L–IL‐7Rαhigh effector‐memory T cells even in the presence of pre‐existing effector‐memory CD4+ cells. Although the total cell numbers of CD4+ cells in established colitic mice were consistently equivalent irrespective of the number of primarily transferred cells, the ratio of primarily and secondarily transferred cells was dependent on the ratio of the transferred cell numbers, but not on the order of the transfer. Of note, we found that primarily transferred CD4+ cells produced significantly lower amounts of IFN‐γ and IL‐17 than CD4+ cells arising from secondary transfer. In conclusion, the continuous generation of colitogenic CD4+ cells that compensate for exhausted CD4+ cells may be one of the mechanisms involved in the persistence of colitis.
Induction of HIV‐specific T and B cell responses with a replicating and conditionally infectious lentiviral vaccine
Authors: Wingard Jeremy B. , Anderson Bart , Weissman Drew 
Published: April 2008

AbstractThe development of an HIV vaccine that induces broad and potent immunity is critically needed. Viruses, including lentiviruses, have been used as vectors for ex vivo transduction of antigens into dendritic cells (DC). We hypothesized that DC transduced with a vector that allows selective infection of DC could induce potent immunity by continually priming DC. A lentiviral vector encoding HIV gag‐pol without env would form viral cores in transduced DC, but would release non‐infectious particles by budding into endosomes and releasing apoptotic bodies or exosomes containing viral cores. DC function by endocytosing DC‐derived apoptotic bodies, and they are specialized in their ability to move endocytic contents into the cytoplasm. We postulated that endocytosis of vector cores could lead to transduction of a second round of DC. In this report, we demonstrate accumulation of viral cores inside transduced DC and show second‐round transduction of immature DC that endocytose transduced DC in vitro. The effectiveness of immunization of mice with transduced DC to induce specific lymphocyte activation was assessed. Mice developed antigen‐specific T cell responses and specific antibodies after immunization. Transduction of DC with a replication‐competent but conditionally infectious lentivirus could be a novel vaccine strategy for HIV.
BINOLate–Magnesium Catalysts for Enantioselective Hetero‐Diels–Alder Reaction of Danishefsky's Diene with Aldehydes
Authors: Du Haifeng , Zhang Xue , Wang Zheng , Bao Hongli , You Tianpa , Ding Kuiling 
Published: April 2008

AbstractAn efficient catalytic enantioselective hetero‐Diels–Alder reaction of Danishefsky's diene with aldehydes using the magnesium binaphthoxide system has been developed, affording a variety of 2‐substituted 2,3‐dihydro‐4H‐pyran‐4‐ones in high yields and with excellenteevalues. The aggregation behavior and nonlinear effect of the catalytic system, as well as the remarkable stereoelectronic effects of ligands on the catalysis, have also been investigated. On the basis of the structure of the isolated reaction intermediate, the stereochemistry of the products, and the information attained from a study of the nonlinear effect, a plausible asymmetric induction model has been proposed. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2008)
Novel Protoilludane Lead Structure for Veterinary Antibiotics: Total Synthesis of Pasteurestins A and B and Assignment of Their Configurations
Authors: Kögl Marion , Brecker Lothar , Warrass Ralf , Mulzer Johann 
Published: April 2008

AbstractTwo novel protoilludane sesquiterpenoids, named pasteurestins A and B (1 and 2), were disclosed in a recent patent. These compounds were reported to exhibit strong and selective activity against some Mannheimia haemolytica strains, pathogen causatives for bovine respiratory disease. These properties qualified 1 and 2 as potential lead structures for new veterinary antibiotics; however, neither the absolute nor the relative configurations had been determined, nor were the compounds available any longer. We thus developed total syntheses of 1 and 2 and clarified their structures and their biological profiles. Key steps were two [2+2+2] CpCo(CO)2‐mediated Vollhardt cycloadditions in both syntheses, and a tin‐mediated asymmetric Reformatsky‐type condensation in the synthesis of 2 with a temperature‐dependent product distribution.(© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2008)
Investigations on the self‐ignition of deposits containing combustibles
Authors: Berger Anka , Krause Ulrich 
Published: April 2008

AbstractSelf‐ignition of deposited combustibles is a possible reason for excessive fires occurring on deposits for recycling materials or on waste dumps. Two series of experiments were performed to assess the hazard of self‐ignition: hot storage tests with different homogeneous mixtures of combustible material and inert material and tests with pockets of combustible material embedded in inert matter. In the first test series considerable exothermicity (ΔT>60K) was observed for mass fractions of combustible material as low as 2.5%. In the second series it could be shown that the heat transfer from a pocket of burning material through the inert matter can ignite a second pocket of combustible matter.Based on the experimental data, numerical simulations were performed to predict self‐ignition on real‐scale waste deposits. For a deposit of specific size and shape, the influence of the ambient temperature on the occurrence of self‐ignition has been investigated. Copyright © 2008 John Wiley & Sons, Ltd.
Numerical Modelling of the Dynamics of Debris Flows and Rock Avalanches
Authors: Hungr Oldrich 
Published: April 2008

AbstractPrediction of velocity and travel distance of potential rapid landslides such as debris flows, debris avalanches, flow slides and rock avalanches is useful for quantitative hazard and risk assessment. This article describes some methods that are becoming available for practical use. The proposed approach uses calibration of relatively simple numerical landslide dynamics models against observed behaviour of real landslide events. Two example cases of runout back‐analyses, selected from a recent International Benchmarking Exercise conducted in Hong Kong, are presented.
Risk Management for Natural Perils – The View of a Global Reinsurer
Authors: Smolka Anselm , Hollnack Dirk 
Published: April 2008

AbstractLoss statistics for natural disasters demonstrate, also after correction for inflation, a dramatic increase in the loss burden since 1950 which was well confirmed by recent disasters like Hurricane Katrina 2005 and the South Asian tsunami 2004. This increase is driven by a concentration of population and values in urban areas, the development of highly exposed coastal and valley regions, the complexity of modern societies and technologies and probably also by the emerging consequences of global warming. This process will continue unless remedial action is taken. This requires a holistic risk management process which starts with hazard identification and moves on to hazard and risk evaluation. Risk evaluation forms the basis for controlling and financing future losses. Natural disaster insurance plays a key role in this context, but also private parties and governments have to share a part of the risk. A main responsibility of governments is to formulate regulations for building construction and land use. The insurance sector and the state have to act together in order to create incentives for building and business owners to take loss prevention measures.