bluuebunny/crossref_metadata_2025_split huggingface dataset:
On Ayin or Mystical Nothingness in the Dialogical Encounter
Authors: Jacobs Jordan 
Published: April 2024

Abstract
In this article I suggest how a moderated form of pause or withdrawal may yield relational fruit in contexts of interpersonal encounter. Consequently, I posit that mystical nothingness – otherwise known as Ayin in Jewish mystical lore – offers a promising way forward, and indicate how it may be synonymous with Buberian concreteness and inclusion. In conclusion, I explore the Tsaddik as a metaphor that highlights not only the relevance of Ayin or nothingness interpersonally, but also its complementarity with the I and Thou encounter as envisaged by Martin Buber.
VASCULAR FLORA OF TOSNENSKY DISTRICT (LENINGRAD REGION, EUROPEAN RUSSIA): COMPOSITION, STRUCTURE AND DYNAMICS
Authors: Saidov N. T. , Konechnaya G. Yu. , Leostrin A. V. 
Published: April 2024

The article presents the first comprehensive assessment of the vascular flora of Tosnensky district (Leningrad region, Northwestern European Russia). In this study, we made the first checklist of vascular plants for this area based on our field observations in 2016–2022, the literature, online sources and herbarium collections. The flora of Tosnensky district consists of 874 species, of which 706 are native, 36 are archaeophytes, 131 are neophytes, and one species has an uncertain status. The list contains information on 43 species new to the district and on one species (Euphrasia micrantha Rchb) new to the flora of Leningrad region. Results show that by the number of native species, Asteraceae, Cyperaceae, Poaceae are leading families; Brassicaceae is the largest in terms of the number of alien species. The native flora is dominated by forest-inhabiting species (55.3% of all species); the largest number of alien species is found on roadsides (42.7%). Most of the native species have a Eurasian range (30.5%), and 20.8% of all alien plants originate from North America. Perennial herbs dominate among both native and alien species (72.9% and 54.2%, respectively). In alien flora of Tosnensky district, there are 59 casual and 55 naturalized non-invasive species, while 14 species have been assigned as invasive. In addition, we provide information on the habitats of 42 species protected in Leningrad region, including three species that are listed in the Red Book of the Russian Federation, namely Isoetes echinospora Durieu, Dactylorhiza baltica (Klinge) Nevski and Lobelia dortmanna L. The flora of Tosnensky district is well listed compared to floras of neighboring territories, however our findings indicate a relatively low proportion of neophytes (15% of all species). This feature can be explained by the low level of development of the transport network that reduces the likelihood of the introduction and spread of neophytes.
The useful lean tissue and appendicular skeletal muscle mass indices related to physical performance in patients undergoing hemodialysis
Authors: Song Yan , Zhang Xuanrui , Lu Jianxia 
Published: April 2024

BACKGROUND: Low muscle quantity commonly seen in patients undergoing hemodialysis (HD) is the key contributor of declined physical performance and increases the risk of morbidity and mortality. However, how to normalize muscle mass for operational criteria in this population remains unknown. OBJECTIVE: To identify the clinically useful whole body lean tissue mass (LTM) and appendicular skeletal muscle mass (ASM) indices pertinent to physical performance in patients undertaking HD. METHODS: Whole body LTM in 38 and ASM in 22 patients undergoing HD were measured by body composition monitor (BCM) and dual-energy X-ray absorptiometry (DXA), respectively. Physical performance was assessed by handgrip strength, the incremental shuttle walk test, sit-to-stand tests, gait speed, Short Physical Performance Battery and Duke Activity Status Index. Besides crude LTM and ASM, the other muscle indices were utilized normalizing for height, height squared, weight, body mass index (BMI), fat mass and body fat%. RESULTS: Regardless of BCM or DXA being used, the relationships between different muscle mass indices and physical function were not consistent. While the most useful LTM index which was strongly associated with physical function involved adjustment for height, the strongest (and most useful) ASM index was normalization for BMI. CONCLUSION: The superiority of adjustment for BMI or height (height2) recommended by international sarcopenia consensus is also suitable for patients undergoing HD. Patients’ BMI or fat mass should be considered in estimating prevalence of sarcopenia and evaluating relationship between muscle mass and physical performance.
Pengaruh Likuiditas dan Profitabilitas terhadap Kebijakan Dividen pada PT Mayora Indah Tbk Periode 2015-2021
Authors: Devy Choirul Puspita 
Published: April 2024

Penelitian ini bertujuan untuk mengetahui pengaruh likuiditas menggunakan current ratio dan profitabilitas menggunakan return on asset terhadap kebijakan dividen pada PT Mayora Indah Tbk tahun 2015-2021. Metode yang digunakan adalah metode kuantitatif. Sample yang digunakan adalah berupa laporan keuangan PT Mayora Indah Tbk selama 7 tahun. Metode analisis menggunakan uji asumsi klasik, analisis regresi, koefisien korelasi, koefisien determinasi dan uji hipotesis dengan bantuan software SPSS 25. Hasil Penelitian ini menunjukkan return on asset berpengaruh signifikan terhadap dividen payout ratio dengan nilai thitung sebesar -15.994 > nilai ttabel yaitu 2,776 dan nilai signifikansi sebesar 0,000 < 0,05. Sementara itu current ratio tidak berpengaruh signifikan terhadap dividen payout ratio dengan nilai thitung sebesar 0,071 < nilai t tabel 2.776 dan nilai signifikansi sebesar 0,172 > 0,05. Sedangkan secara simultan bahwa variabel independen Current Ratio sebagai X1 dan Return On Asset sebagai X2 dalam penelitian ini berpengaruh secara signifikan terhadap variabel dependen Dividend Payout Ratio dengan nilai Fhitung sebesar 0,001 < 0,05 dan nilai Fhitung adalah 63,154 > Ftabel yaitu 5,79.
Pengaruh Citra Merek dan Daya Tarik terhadap Loyalitas Produk Nivea di Piayu Kota Batam
Authors: Siagian Gebby Mirayu , Realize Realize 
Published: April 2024

Apabila perusahaan ingin memperoleh loyalitas yang tinggi dari konsumen, maka perusahaan harus mampu bersaing di dunia bisnis. Perusahaan harus mempunyai karakteristik tersendiri agar bisa menciptakan loyalitas pada konsumen terhadap produk yang ditawarkan hingga bisa menciptakan rasa nyaman sehingga konsumen melakukan proses pembelian yang berulang. Loyalitas konsumen mempunyai beberapa faktor yang bisa mempengaruhinya, diantaranya citra merek dan daya tarik. Penelitian ini bertujuan untuk menganalisis pengaruh citra merek dan daya tarik terhadap loyalitas Produk Nivea Di Piayu Kota Batam. Perancangan penelitian ini menggunakan desain penelitian dan metode penelitian kuantitatif. Teknik pengumpulan data dengan menyebarkan kuesioner kepada 386 responden yakni konsumen yang menggunakan produk Nivea yang berdomisili di keluarahan Tanjung Piayu kecamatan Sei Beduk. Hasil penelitian ini menunjukkan bahwa citra merek dan daya tarik secara parsial dan secara simultan terhadap loyalitas Produk Nivea Di Piayu Kota Batam. Hasil uji koefisien determinasi menunjukkan bahwa pengaruh citra merek dan daya tarik terhadap loyalitas sebesar 8,9 persen, sedangkan sisanya dipengaruhi oleh variabel lain yang tidak diteliti dalam penelitian ini.
Surgical Reconstruction of Sole by Sural Flap among Patients with Loss of Soft Tissue at Distal Portion of Lower Limb
Authors: Islam Md Nazrul , Islam Md Rabiul , Begum Tahmina , Islam Md Moshabbirul 
Published: April 2024

Background: Soft tissue loss on distal one third of leg, around ankle and foot is a big problem. There are many options, but each of them has advantages and disadvantages. Sural fasciocutaneous flap is an option for this problem which has excellent results with minimum morbidity.
Objective: The purpose of the present study was to role of surgical reconstruction of sole by sural flap among patients with loss of soft tissue at distal portion of lower limb.
Methodology: This interventional study was carried out in the Department of Orthopedic Surgery, Ad-Din Sokhina Women’s Medical College, Jashore, Bangladesh from January 2022 to December 2022 for a period of one year. All patients with open fracture on the distal third of the tibia, exposed Achillies tendon, ankle, lateral and medial malleoli or heel reconstruction were performed by sural flap. The flap viability rate and durability of the flap at these sites were evaluated.
Results: 14 patients from 14 to70years old were included in this study. We obtained excellent results with this type of flap in all the patients and success rate was considered as 100% approximately.
Conclusion: With a few limitations, high success rate and collaboratively easy operative procedure; sural flap may be a good option for soft tissue loss at distal leg, ankle and foot.
Journal of National Institute of Neurosciences Bangladesh, July 2023;9(2):127-131
Antioxidant potential of alkaloids and polyphenols of Viola canescens wall using in vitro and in silico approaches
Authors: Ahmad Imtiaz , Huang Pin-Jui , Malak Nosheen , Khan Adil , Asad Fayaz , Chen Chien-Chin 
Published: April 2024

Background:V. canescens Wall, a plant renowned for its ethno-medical properties, was investigated in this study for its antioxidant potential based on its wide therapeutic applications in traditional healthcare systems. The study aimed to assess the antioxidant potential of the plant extract/fractions and to predict the active phytochemicals using computational techniques.Methods: Five fractions were obtained from the crude methanolic extract of Viola canescens, and six concentrations (25, 50, 75, 100, 125, and 150 μg/mL) were prepared for each fraction. The antioxidant activity of these fractions was evaluated using the Tetraoxomolybdate (VI) and 1,1-diphenyl-2-picrylhydrazyl (DPPH) assay. In-silico docking studies and molecular dynamic simulations were conducted to further elucidate the molecular interactions underlying the antioxidant activity.Results: The aqueous extract of V. canescens exhibited significant antioxidant and free radical scavenging activity against DPPH. Additionally, the crude flavonoid extract demonstrated moderate activity with IC50 value of 57.863 μg/mL, indicating potent inhibition of cell growth. In-silico docking studies revealed a strong interaction between emetine and the aromatase protein, suggesting its potential as an antioxidant.Conclusion: The study findings highlight the antioxidant potential of V. canescens extract, indicating its suitability as a source of natural antioxidants. These results suggest its potential application in pharmaceutical preparations aimed at harnessing antioxidant properties for therapeutic purposes.
Identifying early permanent teeth caries factors in children using random forest algorithm
Authors: Masaebi Fatemeh , Ghorbani Zahra , Azizmohammad Looha Mehdi , Deghatipour Marzie , Mohammadzadeh Morteza , Ahsaie Mitra Ghazizadeh , Asadi Fariba , Zayeri Farid 
Published: April 2024

IntroductionEarly permanent dental caries can pose a serious threat to oral health in the coming years. This study aimed to investigate the key factors influencing early dental caries in permanent teeth among first-grade Iranian children.MethodsA cross-sectional study involving 778 randomly selected first-grade children from public schools in Tehran, Iran, was conducted between November 2017 and January 2018. The oral health of the children, evaluated by two trained dentists, was recorded based on the DMFT index. Information on maternal education, gender, dmft index, brushing frequency, dental visits, flossing, and sweet consumption was also collected. The Random Forest method was employed to identify factors associated with early permanent dental caries, and its performance was compared with logistic regression using the Area Under the Curve (AUC) index.ResultsLogistic regression, represented by odds ratios (OR), revealed a significant association between early permanent dental caries and dmft index [OR = 1.13, 95% CI (1.07, 1.20), p-value &lt;0.001], maternal education [OR = 2.04, 95% CI (1.15, 3.62), p-value &lt;0.05], and sweet consumption [OR = 0.59, 95% CI (0.36, 0.98), p-value &lt;0.05]. Random Forest analysis indicated that male gender, higher maternal education, and lower sweet consumption were associated with increased likelihood of being caries-free. Notably, Random Forest demonstrated superior performance (AUC = 0.81) compared to logistic regression (AUC = 0.72).ConclusionEarly permanent dental caries can be effectively managed by caring primary teeth and reducing consumption of sweets. Maternal education emerged as a pivotal factor in mitigating the risk of early permanent dental caries. Therefore, prioritizing these factors and preventing permanent teeth caries in childhood can be remarkably influential in reducing future caries. The usage of the Random Forest algorithm is highly recommended for identifying relevant risk factors associated with early permanent teeth.
AF-React study: Prevalence of thrombotic events in patients with atrial fibrillation receiving NOACs – real-world data analysis from northern Portugal primary healthcare
Authors: Pinto Susana Silva , Teixeira Andreia , Henriques Teresa S. , Monteiro Hugo , Martins Carlos 
Published: April 2024

IntroductionAnticoagulation is recommended for stroke prevention in patients with atrial fibrillation (AF). The guidelines suggest non-vitamin K antagonist anticoagulants (NOACs) as the primary therapy for anticoagulation in AF. Several patient-related factors increase the risk of thrombotic events: elderly individuals, a previous history of stroke, and chronic kidney disease. This study aims to determine the association between NOACs and other patient variables in AF and the occurrence of thrombotic events.MethodsThe database included all adults with the code K78 (ICPC-2 code for AF) who received clinical care in Northern Portugal’s Primary Health Care between January 2016 and December 2018 and were dispensed the same NOAC at the pharmacy.ResultsThe results indicate that 10.2% of AF patients on NOAC anticoagulation experienced a stroke. Furthermore, patients treated with apixaban and dabigatran had higher odds of experiencing a stroke compared to those treated with rivaroxaban. Among patients with the same age, gender, and CHA2DS2Vasc Score, apixaban was significantly associated with a higher likelihood of thrombotic events than rivaroxaban.DiscussionThese results have not been previously reported in studies with real-world data; therefore, a more detailed analysis should be conducted to enhance the validity of these findings.
Effect of liposomal bupivacaine for preoperative erector spinae plane block on postoperative pain following video-assisted thoracoscopic lung surgery: a protocol for a multicenter, randomized, double-blind, clinical trial
Authors: Liao Dawei , Peng Ke , Zhang Yang , Liu Huayue , Xia Zhongyuan , Guo Jian , Wei Fujiang , Chen Chen , Lv Xin , Tong Jianhua , Li Xiaoshuang , Qu Xianfeng , Wang Xiaobin , Wang Yingbin , Ou Shanshan , Liu Hong , Shan Xisheng , Ji Fuhai 
Published: April 2024

BackgroundThere is still a controversy about the superiority of liposomal bupivacaine (LB) over traditional local anesthetics in postoperative analgesia after thoracic surgery. This study aims to determine the effect of LB versus bupivacaine hydrochloride (HCl) for preoperative ultrasound-guided erector spinae plane block (ESPB) on postoperative acute and chronic pain in patients undergoing video-assisted thoracoscopic lung surgery.MethodsThis multicenter, randomized, double-blind, controlled trial will include 272 adult patients scheduled for elective video-assisted thoracoscopic lung surgery. Patients will be randomly assigned, 1:1 and stratified by site, to the liposomal bupivacaine (LB) group or the bupivacaine (BUPI) HCl group. All patients will receive ultrasound-guided ESPB with either LB or bupivacaine HCl before surgery and patient-controlled intravenous analgesia (PCIA) as rescue analgesia after surgery. The numeric rating scale (NRS) score will be assessed after surgery. The primary outcome is the area under the curve of pain scores at rest for 0–72 h postoperatively. The secondary outcomes include the total amount of opioid rescue analgesics through 0–72 h postoperatively, time to the first press on the PCIA device as rescue analgesia, the area under the curve of pain scores on activity for 0–72 h postoperatively, NRS scores at rest and on activity at different time points during the 0–72 h postoperative period, Quality of Recovery 15 scores at 72 h after surgery, and NRS scores on activity on postsurgical day 14 and postsurgical 3 months. Adverse events after the surgery are followed up to the postsurgical day 7, including postoperative nausea and vomiting, fever, constipation, dizziness, headache, insomnia, itching, prolonged chest tube leakage, new-onset atrial fibrillation, severe ventricular arrhythmia, deep venous thrombosis, pulmonary embolism, pulmonary atelectasis, cardiac arrest, ileus, urinary retention, chylothorax, pneumothorax, and organ failure. Analyzes will be performed first according to the intention to treat principle and second with the per-protocol analysis.DiscussionWe hypothesize that LB for preoperative ultrasound-guided ESPB would be more effective than bupivacaine HCl in reducing postoperative pain in video-assisted thoracoscopic lung surgery. Our results will contribute to the optimization of postoperative analgesia regimens for patients undergoing video-assisted thoracoscopic lung surgery.Clinical trial registration:http://www.chictr.org.cn, identifier ChiCTR2300074852.
Investigating silent pauses in connected speech: integrating linguistic, neuropsychological, and neuroanatomical perspectives across narrative tasks in post-stroke aphasia
Authors: Angelopoulou G. , Kasselimis D. , Varkanitsa M. , Tsolakopoulos D. , Papageorgiou G. , Velonakis G. , Meier E. , Karavassilis E. , Pantoleon V. , Laskaris N. , Kelekis N. , Tountopoulou A. , Vassilopoulou S. , Goutsos D. , Kiran S. , Weiller C. , Rijntjes M. , Potagas C. 
Published: April 2024

IntroductionSilent pauses are regarded as integral components of the temporal organization of speech. However, it has also been hypothesized that they serve as markers for internal cognitive processes, including word access, monitoring, planning, and memory functions. Although existing evidence across various pathological populations underscores the importance of investigating silent pauses’ characteristics, particularly in terms of frequency and duration, there is a scarcity of data within the domain of post-stroke aphasia.MethodsThe primary objective of the present study is to scrutinize the frequency and duration of silent pauses in two distinct narrative tasks within a cohort of 32 patients with chronic post-stroke aphasia, in comparison with a control group of healthy speakers. Subsequently, we investigate potential correlation patterns between silent pause measures, i.e., frequency and duration, across the two narrative tasks within the patient group, their performance in neuropsychological assessments, and lesion data.ResultsOur findings showed that patients exhibited a higher frequency of longer-duration pauses in both narrative tasks compared to healthy speakers. Furthermore, within-group comparisons revealed that patients tended to pause more frequently and for longer durations in the picture description task, while healthy participants exhibited the opposite trend. With regard to our second research question, a marginally significant interaction emerged between performance in semantic verbal fluency and the narrative task, in relation to the location of silent pauses—whether between or within clauses—predicting the duration of silent pauses in the patient group. However, no significant results were observed for the frequency of silent pauses. Lastly, our study identified that the duration of silent pauses could be predicted by distinct Regions of Interest (ROIs) in spared tissue within the left hemisphere, as a function of the narrative task.DiscussionOverall, this study follows an integrative approach of linguistic, neuropsychological and neuroanatomical data to define silent pauses in connected speech, and illustrates interrelations between cognitive components, temporal aspects of speech, and anatomical indices, while it further highlights the importance of studying connected speech indices using different narrative tasks.
The prognostic value of ASPECTS in specific regions following mechanical thrombectomy in patients with acute ischemic stroke from large-vessel occlusion
Authors: Zou Yu , Tu Jianglong , Hu Pengxin , Zhao Xihai , Tang Xiaoping 
Published: April 2024

ObjectiveThe aim of this study is to investigate the relationship between the volume of specific regional infarction and the prognosis of patients who undergo mechanical thrombectomy (MT) for acute large vessel occlusion.MethodsIn this study, we collected the clinical and imaging features of patients with unilateral acute anterior circulation ischemic stroke from January 2021 to June 2023 in the Second Affiliated Hospital of Nanchang University. All patients underwent CT perfusion and non-contrast CT scan before MT. The ASPECTS was assessed based on imaging data, and artificial intelligence was used to obtain the percentage of infarction in each of the 10 regions of ASPECTS. According to the modified Rankin Scale, the patients were divided into the good prognosis group and poor prognosis group at the 90-day follow-up. Various indicators in the two groups were compared. Multivariable logistic regression was used to assess the risk factors for poor prognosis. The relationship between core infarction volume and the probability of poor prognosis was plotted to analyze the trend of poor prognosis with changes in the proportion of infarction volume. Finally, a receiver operating characteristic curve was constructed to analyze the predictive ability on poor prognosis.ResultsA total of 91 patients were included, with 58 patients having a good prognosis (mRS ≤ 2) and 33 patients having a poor prognosis (mRS ≥ 3). Multivariate analysis showed that NIHSS score and core infarction involving the internal capsule and M6 region were independent risk factors for poor prognosis. According to the linear correlation, a higher ratio of core infarction volume in the internal capsule or M6 region was linked to an increased risk of a poor prognosis. However, the non-linear analysis revealed that the prognostic impact of core infarction volume was significant when the ratio was greater than 69.7%. The ROC curve indicated that the combination of NIHSS score, infarct location, and the ratio of infarct volume has an AUC of 0.87, with a sensitivity of 84.8% and a specificity of 84.5%.ConclusionIt is important to examine the location and volume of the infarct in the internal capsule and M6 when deciding whether to do a MT.