bluuebunny/crossref_metadata_2025_split huggingface dataset:
Article: EU Merger Control After The Grand Chamber’s Judgment In Commission V. CK Telecoms Investments
Authors: Monti Giorgio 
Published: March 2024

The Grand Chamber set aside the judgment of the General Court in CK Telecoms having found eight errors in law. This paper dissects the judgment of the Grand Chamber to illustrate and explain the differences between the two judgments as well as the significance of these differences. The Grand Chamber clarifies the standard of proof and confirms that the analysis of unilateral effects in oligopoly markets requires a holistic analysis of a number of factors none of which is decisive. While it ratifies the analytical stance of the Commission this does not necessarily indicate that the Commission will prevail as the appeal is heard again at the General Court. Furthermore, the judgment as well as the new techniques used by the Commission suggest that a review of the Horizontal Merger Guidelines is much needed More generally, the clash between the two courts reveals a fundamental difference between judges in the two courts about the role of EU competition law.
EU Merger Regulation, Horizontal Merger Guidelines, unilateral effects, oligopoly, judicial review, telecommunications market, significant impediment of effective competition, standard of proof, competitive constraint, closeness of competition
DIREITOS E GARANTIAS: UMA ANÁLISE DA INSERÇÃO DE PESSOAS COM DEFICIÊNCIA NO MERCADO DE TRABALHO
Authors: Gomes Denilson Soares , Gomes Gustavo Pereira , Palma Vanessa Cristina Lourenço Casotti Ferreira da 
Published: March 2024

As pessoas com deficiência são, como se observa com as repercussões midiáticas, discriminadas e muitas vezes são comparadas como pessoas hipossuficientes ou com déficit intelectual para ingressar no mercado de trabalho. Diante desta problemática, o foco principal deste estudo é apresentar os direitos e garantias legalmente previstas em Tratados Internacionais, na Constituição Federal Brasileira de 1988, e nas leis infraconstitucionais sobre os direitos para a inserção das pessoas com deficiência no mercado de trabalho. Busca ainda apontar a importância da contribuição do mercado para efetivar pessoas com deficiência em sua empresa, sob o viés da segurança à dignidade humana e da inclusão social, expandindo-se à comunicação na comunidade e assegurando mais benesses. Cabe destacar que a pesquisa se encontra em fase inicial, e será dividida em duas fases. No primeiro momento foi utilizado o procedimento metodológico qualitativo, com análises em documentações legais e bibliográficas, almejando contribuir com diversas opiniões e críticas de diferentes autores sobre o panorama da inserção dos PCD’s no mercado de trabalho, como também foram analisadas as leis, decretos, cartas e convenções com o intuito de obter um maior conhecimento sobre os direitos que são garantidos às pessoas deficiente. Ademais, será apontado a importância de ter pessoas deficiente atuando nos espaços e nas relações trabalhistas e a influência da sociologia acerca desse tema. Por fim, pode-se observar pelo estudo que no Brasil, há diversas legislações de amparo para pessoas com deficiências, não obstante a lei de cotas, contudo, numa percepção visual carece de aplicabilidade e efetividade.
Outcomes of liver resection in hepatitis C virus-related intrahepatic cholangiocarcinoma: A systematic review and meta-analysis
Authors: Cheo Feng Yi , Chan Kai Siang , Shelat Vishal G 
Published: March 2024

BACKGROUND
Cholangiocarcinoma is the second most common primary liver malignancy. Its incidence and mortality rates have been increasing in recent years. Hepatitis C virus (HCV) infection is a risk factor for development of cirrhosis and cholangiocarcinoma. Currently, surgical resection remains the only curative treatment option for cholangiocarcinoma. We aim to study the impact of HCV infection on outcomes of liver resection (LR) in intrahepatic cholangiocarcinoma (ICC).
AIM
To study the outcomes of curative resection of ICC in patients with HCV (i.e., HCV+) compared to patients without HCV (i.e., HCV-).
METHODS
We conducted a systematic review and meta-analysis of randomized controlled trials (RCTs) and observational studies to assess the outcomes of LR in ICC in HCV+ patients compared to HCV- patients in tertiary care hospitals. PubMed, EMBASE, The Cochrane Library and Scopus were systematically searched from inception till August 2023. Included studies were RCTs and non-RCTs on patients ≥ 18 years old with a diagnosis of ICC who underwent LR, and compared outcomes between patients with HCV+ vs HCV-. The primary outcomes were overall survival (OS) and recurrence-free survival. Secondary outcomes include perioperative mortality, operation duration, blood loss, intrahepatic and extrahepatic recurrence.
RESULTS
Seven articles, published between 2004 and 2021, fulfilled the selection criteria. All of the studies were retrospective studies. Age, incidence of male patients, albumin, bilirubin, platelets, tumor size, incidence of multiple tumors, vascular invasion, bile duct invasion, lymph node metastases, and stage 4 disease were comparable between HCV+ and HCV- group. Alanine transaminase [MD 22.20, 95%confidence interval (CI): 13.75, 30.65, P < 0.00001] and aspartate transaminase levels (MD 27.27, 95%CI: 20.20, 34.34, P < 0.00001) were significantly higher in HCV+ group compared to HCV- group. Incidence of cirrhosis was significantly higher in HCV+ group [odds ratio (OR) 5.78, 95%CI: 1.38, 24.14, P = 0.02] compared to HCV- group. Incidence of poorly differentiated disease was significantly higher in HCV+ group (OR 2.55, 95%CI: 1.34, 4.82, P = 0.004) compared to HCV- group. Incidence of simultaneous hepatocellular carcinoma lesions was significantly higher in HCV+ group (OR 8.31, 95%CI: 2.36, 29.26, P = 0.001) compared to HCV- group. OS was significantly worse in the HCV+ group (hazard ratio 2.05, 95%CI: 1.46, 2.88, P < 0.0001) compared to HCV- group.
CONCLUSION
This meta-analysis demonstrated significantly worse OS in HCV+ patients with ICC who underwent curative resection compared to HCV- patients.
Impact of metabolic dysfunction-associated steatotic liver disease on COVID-19 hospitalizations: A propensity-matched analysis of the United States
Authors: Sohail Abdullah , Ali Hassam , Patel Pratik , Subramanium Subanandhini , Dahiya Dushyant Singh , Sohail Amir H , Gangwani Manesh Kumar , Satapathy Sanjaya K 
Published: March 2024

BACKGROUND
Metabolic dysfunction-associated steatotic liver disease (MASLD), formally known as nonalcoholic fatty liver disease, is the most common chronic liver disease in the United States. Patients with MASLD have been reported to be at a higher risk of developing severe coronavirus disease 2019 (COVID-19) and death. However, most studies are single-center studies, and nationwide data in the United States is lacking.
AIM
To study the influence of MASLD on COVID-19 hospitalizations during the initial phase of the pandemic.
METHODS
We retrospectively analyzed the 2020 National Inpatient Sample (NIS) database to identify primary COVID-19 hospitalizations based on an underlying diagnosis of MASLD. A matched comparison cohort of COVID-19 hospitalizations without MASLD was identified from NIS after 1: N propensity score matching based on gender, race, and comorbidities, including hypertension, heart failure, diabetes, and cirrhosis. The primary outcomes included inpatient mortality, length of stay, and hospitalization costs. Secondary outcomes included the prevalence of systemic complications.
RESULTS
A total of 2210 hospitalizations with MASLD were matched to 2210 hospitalizations without MASLD, with a good comorbidity balance. Overall, there was a higher prevalence of severe disease with more intensive care unit admissions (9.5% vs 7.2%, P = 0.007), mechanical ventilation (7.2% vs 5.7%, P = 0.03), and septic shock (5.2% vs 2.7%, P <0.001) in the MASLD cohort than in the non-MASLD cohort. However, there was no difference in mortality (8.6% vs 10%, P = 0.49), length of stay (5 d vs 5 d, P = 0.25), and hospitalization costs (42081.5 $ vs 38614$, P = 0.15) between the MASLD and non-MASLD cohorts.
CONCLUSION
The presence of MAFLD with or without liver cirrhosis was not associated with increased mortality in COVID-19 hospitalizations; however, there was an increased incidence of severe COVID-19 infection. This data (2020) predates the availability of COVID-19 vaccines, and many MASLD patients have since been vaccinated. It will be interesting to see if these trends are present in the subsequent years of the pandemic.
Innovación educativa y comunidades de aprendizaje
Authors: Logroño-Herrera Lorena , Peralvo-Arequipa Carmen 
Published: March 2024

Introducción: La innovación educativa y las comunidades de aprendizaje permiten crear sistemas para determinar posibles soluciones y mejoras en los resultados de aprendizajes. Y responder a las necesidades de la sociedad actual, entendiendo que la escuela no puede estancarse y seguir reproduciendo prácticas educativas tradicionalistas.
Objetivo: Establecer la aplicación de procesos de innovación educativa a través de la incorporación de las comunidades de aprendizaje para la adquisición de mejoras en el proceso pedagógico del cuarto año de educación general básica en la unidad educativa del Cantón Pujilí, año lectivo 2021-2022.
Método: Se trabajó bajo el paradigma cuantitativo, el método aplicado es el inductivo, la técnica es la entrevista, con su instrumento guía de entrevista. La población estuvo constituida por una autoridad (rector) y 3 docentes del cuarto año de EGB de la Institución Educativa.
Resultados: Se determinó la necesidad de capacitar a los docentes sobre innovación educativa, con la finalidad que cambien sus prácticas tradicionales, el orden del aula, las relaciones interpersonales y la organización de la institución educativa.
Conclusión: Se concluyo que las pocas capacitaciones relacionadas con innovación educativa y la integración de las comunidades de aprendizaje, ha conducido a prácticas educativas monótonas que ha perjudicado los procesos educativos
Palabras Clave: Innovación educativa, comunidades de aprendizaje, enseñanza-aprendizaje, formación integral.
MEROSOTNYA PEREKONOMIAN NASIONAL, PENYEBAB, TENDENSI KE ARAH KRISIS EKONOMI DAN SOLUSINYA
Authors: Santoso Bibit 
Published: March 2024

Perubahan ekonomi yang terjadi secara cepat tersebut mengarah pada turunnva nilai tukar mata uang dan harga kebutuhan pokok yang semakin tinggi. Krisis ekonomi dapat melanda suatu negara apabila perubahan perekonomian sudah tidak dapat dibendung lagi, contoh, Krisis Ekonomi 1997 memporak-porandakan perekonomian global. tidak memandang perekonomian negara berkembang ataupun negara maju. Walaupun krisis ini lebih populer dikenal dengan sebutan krisis Asia tetapi tidak hanya negara Asia saja yang terkena dampakya, semua terkena dampak dari krisis ini, yang pada akhirnya berdampak pada menurunnya kualitas kesejahteraan tiap warga negara.
Pelemahan pertumbuhan ekonomi pada triwulan I 2015 terutama didorong melemahnya kinerja beberapa komponen permintaan domestik, seperti konsumsi lembaga non profit, konsumsi pemerintah dan investasi pada sektor bangunan. Pemerintah Indonesia perlu melakukan berbagai langkah-langkah sebagai upaya mengatasi dan meminimalisir dampak perlambatan ekonomi China. Langkah jangka pendek maupun jangka panjang perlu dilakukan secara terstruktur dan terukur agar mampu mengatasi masalah lain secara optimal. Dampak jangka pendek dari perlambatan ekonomi China adalah mengakibatkan tekanan terhadap ekspor Indonesia terhadap China, sementara impor Indonesia dari China tidak dapat terbendung sehingga neraca pembayaran tertekan. Untuk menjaga stabilitas kondisi perekonomian dalam negeri, maka dalam jangka pendek yang dapat dilakukan adalah menjaga daya beli masyarakat, salah satunya dengan menjaga tingkat inflasi. Besarnya ketergantungan dan konsumerisme masyarakat terhadap produk China berdampak pada timpangnya neraca perdagangan
Indonesia - China. Kondisi ini dalam jangka panjang akan menyebabkan lemahnya fundamental perekonomian Indonesia, sehingga rentan terhadap fluktuasi perekonomian negara lain. Mengurangi ketergantungan impor adalah agenda wajib yang harus dilakukan pemerintah dalam jangka panjang.
Substitusi Rumput Laut Eucheuma Cottonii Dalam Pembuatan Mie Basah.
Authors: Mehang Yeheskiel Djawa , Tega Yatris Rambu 
Published: March 2024

Mie merupakan suatu produk makanan yang sangat disukai dan banyak dikonsumsi oleh masyarakat Indonesia. Mie bukanlah suatu makanan yang istimewa, dikarenakan pada umumnya kandungan gizi pada produk mie dan olahannya masih sangat rendah, terutama pada kandungan protein. Untuk mengetahui kandungan proksimat pada mie basah yang disubstitusikan dengan rumput laut Eucheuma cottonii dengan konsentrasi yang berbeda 20%, 25%, dan 30% dan Untuk mengetahui konsentrasi terbaik pada pembuatan mie basah. Penelitian menggunakan rancangan acak lengkap (RAL) yang terdiri dari 3 perlakuan 20%, 25%, 30% masaing-masing perlakuan dilakukan 4 kali ulangan sehingga diperoleh jumlah satuan percobaan sebanyak 12 unit percobaan. Tah pembuatan mie basah dimulai dengan Persiapan bahan baku rumput laut Eucheuma cottonii, Persiapan bahan baku rumput laut Eucheuma, Penghalusan rumput laut dengan penambahan air 1:1, Pencampuran bahan baku dengan konsentrasi rumput laut 20%, 25%, 30%, Pencetakan mie. Produk yang dihasailkan kemudian di lakukan analisis karakteristik kimia meliputi kadar air, karbohidrat, protein, kadar abu, kadar lemak. Berdasarkan hasil uji statistik ANOVAmenunjukan pelakuan konsentrasi 20% mie basah yang berbeda memberikan pengaruh nyata (p<0,05) terhadap karakteristik kimia mie basah yang diperoleh.
Penguatan Kapasitas Lembaga Pemberdayaan Masyarakat Desa (LPMD) Polengan, Srumbung, Kabupaten Magelang Berbasis DESTANA
Authors: Septiani Yustirania , Khabibah Nibras Anny , Sugiharti Rr. Retno , Ayuningtyas Andini 
Published: March 2024

Penguatan Kapasitas LPMD (Lembaga Pemberdayaan Masyarakat Desa) Desa Polengan Kec. Srumbung berbasis DESTANA ini bertujuan untuk mensosialisasikan suatu metode atau cara untuk menanggulangi bencana yang mungkin bisa terjadi pada masyarakat di Desa Polengan. Karena Desa Polengan merupakan kumpulan pedukuhan yang terletak di kaki Gunung Merapi sebelah barat, kira-kira berada pada radius 11 Km dari puncak gunung. Sehingga menjadi Wilayah yang termasuk kawasan rawan bencana (KRB) III,. Kerawanan terutama terkait gunung berapi, wilayah KRB III (merah) yang merupakan kawasan yang sering terlanda awan panas, aliran lava, lontaran bom vulkanik, gas beracun maupun guguran batu (pijar). Adapun cara yang digunakan dalam pemberdayaan masyarakat menuju siaga bencana adalah dengan memperkuat kapasitasnya dalam hal Tanggap darurat yakni serangkaian kegiatan yang dilakukan dengan segera pada saat kejadian bencana untuk menangani dampak buruk yang ditimbulkan (penyelamatan dan evakuasi korban, harta benda, pemenuhan kebutuhan dasar, perlindungan, pengurusan pengungsi, penyelamatan, serta pemulihan prasarana dan sarana). Metode yang digunakan dalam pelaksanaan berupa metode penyuluhan dengan menggandeng Pemerintah desa Polengan , dan BPBD Kab. Magelang sebagai Narasumber, yang mengisi Kepala Pelaksana BPBD Kab. Magelang Edy Wasono, S.H beserta jajarannya. Sehingga LPBD Polengan mampu menjadi garda terdepan Ketika terjadi bencana terutama terkait gunung berapi dan kedepan mampu menginisiasi menjadi DESA TANGGAP BENCANA (DESTANA) di Desa Polengan, Srumbung, Muntilan Kabupaten Magelang.
Percepatan Transformasi Nagari Talang Babungo menuju Pengembangan Pariwisata Berkelanjutan melalui Pelatihan Penguatan Infrastruktur dan Akses Internet
Authors: Rasyidah  , Erianda Aldo , Hidayat Rahmat , Alde Alanda  , Mooduto Hanriyawan Adnan 
Published: March 2024

Transformasi digital sangat penting untuk mengatasi berbagai masalah pembangunan. Transformasi digital, termasuk sektor pariwisata, dipengaruhi oleh globalisasi, perilaku konsumen yang berubah, perubahan iklim dan lingkungan, dan kemajuan teknologi yang cepat. Dengan sebagian besar wilayahnya pedesaan, Indonesia memiliki banyak potensi untuk pariwisata. Maka penting penerapan topologi jaringan internet desa wisata memiliki efek positif dan signifikan terhadap percepatan pengembangan destinasi wisata berkelanjutan di Nagari Talang Babungo. Ini dapat dilihat dari peningkatan kualitas layanan internet, peningkatan kunjungan wisatawan, peningkatan pendapatan masyarakat, peningkatan kesejahteraan masyarakat, dan peningkatan pelestarian lingkungan. Dengan mengidentifikasi dan menganalisis kebutuhan, perancangan jaringan yang efektif dan murah dapat dicapai. hotspot-net menggunakan router yang dilengkapi dengan sistem operasi Mikrotik untuk mengimplementasikan sistem ini. Untuk memanfaatkan transisinya, Access Point Wireless digunakan sebagai infrastruktur jaringan. Salah satu fitur jaringan internet desa wisata ini adalah filter DNS, yang memungkinkan untuk memblokir situs web yang bertentangan dengan norma budaya dan agama masyarakat lokal. Selain itu, jaringan internet desa wisata ini dilengkapi dengan AdGuard, yang memiliki kemampuan untuk menghapus iklan yang mengganggu pengguna internet. Selain itu, jaringan internet desa wisata ini memiliki webserver yang menyediakan profil, fasilitas, produk, dan kegiatan desa wisata.
Impact of Work from Home on Sri Lankan Teachers’ Teaching and Learning Process
Authors: Weerasinghe WDPD , Wickramasinghe Mihiri 
Published: March 2024

Aims: This paper aims to analyze the impact of working from home on teachers' teaching and learning processes in a chosen Province in Sri Lanka From teachers’ perspective.
Study Design: This study follows the exploratory type and a questionnaire survey will be used to collect data.
Methodology: The data were analyzed using descriptive statistics to understand the teaching and learning process of teachers in the chosen province in Sri Lanka and Regression analysis to understand the impact of an independent variable on the study’s dependent variable.
Results: The positive effect of Infrastructure Facilities, Family Interference, and Technology Literacy on teachers' online teaching and learning process were statistically significant at 0.05 level. But, the significant value of Social Distractions was 0.764 which is above the standard level. Hence the impact of Social Distractions on online teaching and learning process was statistically insignificant at 0.05 level. Furthermore, infrastructure facilities were a highly influential factor in the online teaching and learning process.
Conclusion: The research was limited to one province in Sri Lanka, and thus, it may not be possible to conclude the results of an entire country. In this modern world schools in developing countries should be adapted to these new technological changes. Teachers, administration, and Government may utilize the findings of this study in their decision-making. The study shows useful perceptions of how work from home impacts teachers' teaching and learning processes.
Evaluating the Effects of Fertilizers and Bio-stimulants on Field Performance of Amaranthus dubius
Authors: Aluko Matthew, 
Published: March 2024

Aims: The continuous increase in human population warrants more food production. Amaranthus spp. is one of the most consumed leafy vegetables globally. A field experiment was conducted at the Teaching and Research Farm of Ekiti State University, Ado-Ekit Nigeria to assess the effects of fertilizers and bio-stimulants on the growth and performance of Amaranthus dubius.
Methodology: The experiment was laid out in a randomized complete block design (RCBD) with three replicates. The Amaranthus dubius seeds were sown under open field conditions and the treatments included aqueous moringa leaf extract (AMLE), NPK 15:15:15, poultry manure, grand humus, and super gro which were applied at 2, 4, and 6 weeks after sowing WAS. Data were collected 7 days after each application on on leaf area (cm3), plant height (cm), stem girth (cm), and total fresh biomass (g). The collected data were analysed using IRRI STAR 2.0.
Results: The result revealed that all the treatments were significantly different (P>0.05) for all the parameters studied. AMLE recorded the highest value for all the parameters studied while control had the lowest values. For the total fresh biomass, AMLE recorded the highest mean value (1981.33) followed by NPK 15:15:15 (1535.00) and poultry manure (140.67) respectively while control had the least mean value (640.33).
Conclusion: Amaranthus dubius was a short live plant response to AMLE and NPK 15:15:15 than the other treatment applied. It is therefore recommended that AMLE should be applied to boost the performance of Amaranthus dubius.
Evaluation of Various Therapeutic Approaches in Treating Medication-related Osteonecrosis of the Jaw: A Systematic Review
Authors: Andrade Mário Jorge Augusto de , Leal Marilia de Oliveira Coelho Dutra , Jodas Claudio Roberto Pacheco , Machado Renato Assis , Bachesk Andressa Bolognesi , Teixeira Rubens Gonçalves 
Published: March 2024

Background and Aims: Medication-related osteonecrosis of the jaws (MRONJ) is a significant and potentially debilitating side effect caused by antiresorptive and antiangiogenic drugs, which can lead to bone exposure in the oral cavity. However, the management of this condition remains controversial, with adjuvant therapies being employed despite limited scientific evidence. This systematic review aimed to identify effective therapeutic procedures for treating MRONJ.
Methodology: A literature search was conducted without any temporal limitations. The PRISMA protocol was followed. To identify relevant studies, we developed electronic search strategies for various bibliographic databases, as Cochrane, Embase, PubMed, Scopus, and Web of Science. It was conducted a comprehensive analysis of 30 studies involving 2,079 patients from 35 countries to evaluate the effectiveness of various treatment approaches for MRONJ.
Results: The systematic review revealed that long-term use of Zoledronic acid for approximately 452.04 months (±27.41; 12-102) exposed many patients (n=772) to the risk of MRONJ. Similarly, Alendronate use for approximately 104.4 months (±60.16; 6-180) also posed a risk, affecting 650 patients, while Pamidronate use for about 20.74 months (±4.94; 6-96) was associated with MRONJ risk in 121 patients. Among the treatment approaches, conservative surgical management was the most frequently employed (27.92%), followed by local debridement (13.57%) and conservative treatment (11.21%). Treatment complications were observed in 13.03% of cases, with the most frequent complications being resistant or worsening clinical stage of osteonecrosis, followed by incomplete mucosal healing or dehiscence and mental nerve injury.
Conclusion: While conservative surgical management, local debridement, and conservative treatment are commonly utilized approaches, the treatment of MRONJ lacks a standardized consensus due to the scarcity of scientific evidence. Further research and comprehensive studies are imperative to establish effective therapeutic strategies for managing this condition.