bluuebunny/crossref_metadata_2025_split huggingface dataset:
Evaluation of the Root Rupture Method for Controlling Belowground Spread of the Oak Wilt Pathogen (Bretziella fagacearum) in Northeast Wisconsin, USA
Authors: Yang Anna , Haugen Linda M , Mausel David L , Lampereur John , Stueck Tommy , Montgomery Rebecca A , Juzwik Jennifer 
Published: March 2024

Abstract
Oak wilt, caused by the pathogen Bretziella fagacearum, is a destructive disease on oak (Quercus) species in the United States. Established methods to control the belowground spread of oak wilt are not appropriate in all circumstances; thus, forest health managers have a strong need for alternative methods for disease control. We evaluated the effectiveness of operational stump excavation treatments (i.e., “root rupture” method) applied between 2004 and 2014 to control belowground spread of oak wilt on two forests in northeast Wisconsin, USA. The root rupture method achieved a high level of disease control (≥85% of evaluated disease infection centers) for 5 years by harvesting red oak trees within infection centers and uprooting the stumps and associated root mass. The likelihood of disease control success depended on the initial size of the infection center that was treated, with larger infection centers being less likely to be contained with a single treatment than small infection centers. This study highlights the importance of early detection and prompt management in oak wilt suppression programs.
Study Implications: Forest management agencies and organizations in the North Central United States continue to face oak wilt epidemics. No single tool or treatment method ensures complete containment of oak wilt; thus, most managers carefully consider all the tools and techniques available to them and determine what best suits their budget and land use priorities. Stump excavation (i.e., “root rupture” method) is a cost-effective treatment for halting belowground spread of the oak wilt fungus, Bretziella fagacearum, that can achieve a high level of disease control. In northern red oak (Quercus rubra) stands with high economic value, this treatment can be applied as a group selection, with the value of the timber potentially offsetting the cost of treatment. The opportunity for complete disease control decreases as oak wilt infection centers increase in size; thus, monitoring and early control actions are critical.
False-positive HIV screening test in a healthcare student
Authors: Quigley J , Hussain T , Arthur C 
Published: March 2024

Summary
This case report describes a 22-year-old female Ambulance Technician student who displayed human immunodeficiency virus (HIV) false positivity following a recent hepatitis B vaccination. Occupational health clinicians who work in a healthcare setting (with healthcare staff and/or students) should be aware of the possibility of false-positive HIV screening test results, and where a false positive is suspected, they should consider what the underlying cause could be and should consider whether further medical investigation is required.
The Enterics for Global Health (EFGH) Shigella Surveillance Study in The Gambia
Authors: Conteh Bakary , Badji Henry , Jallow Abdoulie F , Karim Mehrab , Manneh Alhagie , Keita Belali , Sarwar Golam , Ceesay Bubacarr E , Jarju Sheikh , Jabang Abdoulie M J , Baldeh Ebrima , Ikumapayi Usman N , Secka Ousman , Antonio Martin , Roca Anna , D’Alessandro Umberto , Kotloff Karen L , Hossain M Jahangir 
Published: March 2024

Abstract

Background
The Gambia, located in West Africa, is one of 7 country sites conducting the Enterics for Global Health (EFGH) Shigella Surveillance Study to establish incidence and consequence of Shigella-associated medically attended diarrhea among children 6–35 months old.

Methods
Here we describe the study site and research experience, sociodemographic characteristics of the study catchment area, facilities of recruitment for diarrhea case surveillance, and known care-seeking behavior for diarrheal illness. We also describe The Gambia's healthcare system and financing, current vaccine schedule and Shigella vaccine adaptation, local diarrhea management guidelines and challenges, and antibiotic resistance patterns in the region.

Conclusions
The EFGH study in The Gambia will contribute to the multisite network of Shigella surveillance study and prepare the site for future vaccine trials. In addition, the data produced will inform policy makers about prevention strategies and upcoming Shigella vaccine studies among children in this setting.
Controlling Images of Neighborhoods in Gentrification Coverage
Authors: Rucks-Ahidiana Zawadi 
Published: March 2024

Abstract
Prior literature has largely used the concept of “controlling images” to explain how the news media and other institutions use racialized and gendered stereotypes to control marginalized groups. This article extends the concept of controlling images to neighborhoods using 583 newspaper articles about gentrification in San Francisco. Using qualitative and spatial analysis, I demonstrate how controlling images exist in media through representations, underrepresentations, and omissions in the form of three controlling images of neighborhoods: “The apolitical Asiantown” appears through the omission of Asian neighborhoods and Asian residents of other gentrifying neighborhoods, “the immigrant barrio” through the underrepresentation of Latinx residents and centering of White residents in Latinx neighborhoods, and “the violent ’hood” through the focus on issues of blight, crime, and violence in Black neighborhoods. The findings contribute to our understanding of how institutional racism operates not only through racist representations, but also through racist exclusions.
Unwitting Accomplices: Equal Treatment and the Perpetuation of Racialized Information Inequality in School Choice
Authors: Faude Sarah 
Published: March 2024

Abstract
In public education, racially segregated schools are now often understood as a natural result of a messy mix of failed policies and parent decisions. However, parent decisions and school choice are both constrained by districts. In the case of Boston Public Schools (BPS), the staff hired to support “well-informed choices” do not provide information to families—including those who need it most—even when it could mitigate known inequities. Using data from semi-structured interviews with 37 staff, participant observation in registration sites, a supplemental survey of 1,887 registering families, and district administrative data on all registering families, I find that BPS constrains the actions of frontline staff, making them unwitting proponents of the fallacy of choice. The equal treatment of families who come with unequal access to the registration and choice systems protects racial privilege in relation to schools and harms both families of color and the staff of color who work with them. This racism of omission enacted within the choice apparatus causes staff and families to focus on the selection process rather than the limited and racialized access to the public good of schools.
Organoid-based personalized medicine: from tumor outcome prediction to autologous transplantation
Authors: Soto-Gamez Abel , Gunawan Jeremy P , Barazzuol Lara , Pringle Sarah , Coppes Rob P 
Published: March 2024

Abstract
Inter-individual variation largely influences disease susceptibility, as well as response to therapy. In a clinical context, the optimal treatment of a disease should consider inter-individual variation and formulate tailored decisions at an individual level. In recent years, emerging organoid technologies promise to capture part of an individual’s phenotypic variability and prove helpful in providing clinically relevant molecular insights. Organoids are stem cell-derived 3-dimensional models that contain multiple cell types that can self-organize and give rise to complex structures mimicking the organization and functionality of the tissue of origin. Organoids therefore represent a more faithful recapitulation of the dynamics of the tissues of interest, compared to conventional monolayer cultures, thus supporting their use in evaluating disease prognosis, or as a tool to predict treatment outcomes. Additionally, the individualized nature of patient-derived organoids enables the use of autologous organoids as a source of transplantable material not limited by histocompatibility. An increasing amount of preclinical evidence has paved the way for clinical trials exploring the applications of organoid-based technologies, some of which are in phase I/II. This review focuses on the recent progress concerning the use of patient-derived organoids in personalized medicine, including (1) diagnostics and disease prognosis, (2) treatment outcome prediction to guide therapeutic advice, and (3) organoid transplantation or cell-based therapies. We discuss examples of these potential applications and the challenges associated with their future implementation.
Improving Calculations of Electron Eye-lens Operational Dose Coefficients Using the Monte Carlo Codes PENELOPE and MCNP6.2
Authors: Dubeau Jacques , Sun Jiansheng , Djeffal Salah , Ali Fawaz 
Published: March 2024

Abstract
After considering epidemiological studies on the induction of cataracts in individuals exposed to radiation, the International Commission on Radiological Protection recommended, in 2012, a reduction in the annual eye-dose limit of occupationally exposed workers. This imposed higher performance demands on existing dosimetry systems and the development of new dosimetry technologies. The operational quantity to be measured is H
p(3), the personal dose equivalent at a depth of 3 mm in an ICRU 4-element tissue cylinder 20 cm in height and 20 cm in diameter. The conversion coefficients per unit incident fluence, H
p(3)/Φ, were calculated using Monte Carlo simulation codes. In the case of incident electrons, the literature shows that the resulting coefficients depend on the electron transport options selected for the Monte Carlo simulations as well as the tally zone thickness. In this study, electron operational eye-lens dose coefficients were calculated using MCNP6.2 in its default settings and by invoking the single-event feature. The results were compared to those from PENELOPE, a well-known code for its enhanced accuracy in handling low-energy electron transport. The results are in agreement for the entire energy range for these two series of simulations, but differences are found with previously published dose coefficients in the literature. This impacts the calibration of dosimeters for electrons and may require a change in the commonly accepted dose coefficients.
Circumferential resection margin rates in esophageal cancer resection: oncological equivalency and comparable clinical outcomes between open versus minimally invasive techniques – a retrospective cohort study
Authors: Patel Pranav H. , Patel Nikhil M. , Doyle Joseph P. , Patel Hina K. , Alhasan Yousef , Luangsomboon Alfa , Petrou Nikoletta , Bhogal Ricky H. , Kumar Sacheen , Chaudry Mohammed A. , Allum William H. 
Published: March 2024

Background:
Radical surgery for esophageal cancer requires macroscopic and microscopic clearance of all malignant tissue. A critical element of the procedure is achieving a negative circumferential margin (CRM) to minimize local recurrence. The utility of minimally invasive surgery poses challenges in replicating techniques developed in open surgery, particularly for hiatal dissection in esophago-gastrectomy. In this study, the technical approach and clinical and oncological outcomes for open and laparoscopic esophago-gastrectomy are described with particular reference to CRM involvement.

Materials and methods:
This cohort study included all patients undergoing either open or laparoscopic esophago-gastrectomy between January 2004 and June 2022 in a single tertiary center. A standard surgical technique for hiatal dissection of the esophago-gastric junction developed in open surgery was adapted for a laparoscopic approach. Clinical parameters, length of stay (LOS), postoperative complications, and mortality data were collected and analyzed by a Mann–Whitney U or Fisher’s exact method.

Results:
Overall 447 patients underwent an esophago-gastrectomy in the study with 219 open and 228 laparoscopic procedures. The CRM involvement was 18.8% in open surgery and 13.6% in laparoscopic surgery. The 90-day-mortality for open surgery was 4.1 compared with 2.2% for laparoscopic procedures. Median Intensive care unit (ITU), inpatient LOS and 30-day readmission rates were shorter for laparoscopic compared with open esophago-gastrectomy (ITU: 5 versus 8 days, P=0.0004; LOS: 14 versus 20 days, P=0.022; 30-day re-admission 7.46 versus 10.50%). Postoperative complication rates were comparable across both cohorts. The rates of starting adjuvant chemotherapy were 51.8 after open and 74.4% in laparoscopic esophago-gastrectomy.

Conclusion:
This study presents a standardized surgical approach to hiatal dissection for esophageal cancer. The authors present equivalence between open and laparoscopic esophago-gastrectomy in clinical, oncological, and survival outcomes with similar rates of CRM involvement. The authors also observe a significantly shorter hospital length of stay with the minimally invasive approach.
Informal Family Care Partner Well-Being Is Diminished in End-Stage Liver Disease
Authors: Hansen Lissi , Chang Michael F. , Hiatt Shirin , Dieckmann Nathan F. , Lee Christopher S. 
Published: March 2024

Background
Chronic liver disease is a significant global neglected public health problem. End-stage liver disease is associated with substantial symptom complexity, disability, and care needs that require assistance from informal family care partners. Research on these care partners' caregiver burden or strain, symptoms, and quality of life is sparse and has not focused on these variables as co-occurring or in the context of the quality of the relationship care partners have with the patients.

Objectives
The purpose of this study was to provide a collective presentation of patterns and determinants of well-being as measured by caregiver strain, depression, sleep, and quality of life in a cohort of informal family care partners for adult outpatients with end-stage liver disease.

Methods
Care partners (aged >18 years) were recruited from two liver clinics within two tertiary healthcare systems and invited to complete a cross-sectional survey. They completed the Multidimensional Caregiver Strain Index, Patient Health Questionnaire, Pittsburgh Sleep Quality Index, Short Form Health Survey, and Mutuality Scale. Descriptive statistics and latent class mixture modeling were used to analyze these data.

Results
The sample was predominantly female and White. The well-being of care partners was diminished. Three distinct classes of well-being were identified: mildly diminished (53.2%), moderately diminished (39.0%), and severely diminished (7.8%). Those at a greater risk of worse well-being were younger and spouses and had poorer relationship quality with the patients.

Discussion
To improve the well-being of care partners in moderately and severely diminished classes, assessing and addressing caregiver strain and co-occurring symptoms is essential. Addressing the strain and symptoms has the potential to maintain or optimize care partners' ability to provide care to patients. Future researchers should include longitudinal and dyadic studies to examine how patients' disease progression and symptoms may affect family care partners' well-being and vice versa.
An Analysis of Incident Reports Related to Electronic Medication Management: How They Change Over Time
Authors: Kinlay Madaline , Zheng Wu Yi , Burke Rosemary , Juraskova Ilona , Ho Lai Mun (Rebecca) , Turton Hannah , Trinh Jason , Baysari Melissa T. 
Published: March 2024

Objective
Electronic medication management (EMM) systems have been shown to introduce new patient safety risks that were not possible, or unlikely to occur, with the use of paper charts. Our aim was to examine the factors that contribute to EMM-related incidents and how these incidents change over time with ongoing EMM use.

Methods
Incidents reported at 3 hospitals between January 1, 2010, and December 31, 2019, were extracted using a keyword search and then screened to identify EMM-related reports. Data contained in EMM-related incident reports were then classified as unsafe acts made by users and the latent conditions contributing to each incident.

Results
In our sample, 444 incident reports were determined to be EMM related. Commission errors were the most frequent unsafe act reported by users (n = 298), whereas workarounds were reported in only 13 reports. User latent conditions (n = 207) were described in the highest number of incident reports, followed by conditions related to the organization (n = 200) and EMM design (n = 184). Over time, user unfamiliarity with the system remained a key contributor to reported incidents. Although fewer articles to electronic transfer errors were reported over time, incident reports related to the transfer of information between different computerized systems increased as hospitals adopted more clinical information systems.

Conclusions
Electronic medication management–related incidents continue to occur years after EMM implementation and are driven by design, user, and organizational conditions. Although factors contribute to reported incidents in varying degrees over time, some factors are persistent and highlight the importance of continuously improving the EMM system and its use.
Speech Outcomes After Palatal Lengthening Via Double Opposing Buccinator Myomucosal Flaps
Authors: Monte Thais Miguel , Raposo-Amaral Cesar A. , Sabbag Anelise , Gil André , Menezes Priscila T. , Raposo-Amaral Cassio E. 
Published: March 2024

Background
Palatal lengthening is becoming a first-line treatment choice for cleft patients with velopharyngeal insufficiency (VPI). As cleft palate–related surgical outcomes are age dependent, speech outcomes may be similarly affected by patient age at the time of treatment. The primary goal of this study is to determine whether there are age-related speech outcome differences when double opposing buccinator myomucosal flaps are used as part of a palatal lengthening protocol and whether these outcome differences preclude utilization of this technique for specific patient age groups.

Methods
A retrospective study was performed on consecutive nonsyndromic patients with VPI who underwent treatment using double opposing buccinator myomucosal flaps at our hospital between 2014 and 2021. Patients who completed the 15-month follow-up were stratified by age. Group A aged between 2 and 7 years (n = 14), group B aged 8 and 18 years (n = 23), and group C aged older than 18 years (n = 25) were included. Standardized perceptual speech evaluations and nasopharyngoscopy were performed. Hypernasality, soft palate mobility, and lateral palatal wall mobility were assessed both preoperatively and at a 15-month postoperative interval. Complications were also recorded. The χ2 test was used for statistical comparison.

Results
All of the age-stratified patient groups in this study showed significant improvement in hypernasality, soft palate mobility, and lateral wall mobility (P < 0.01), with no statistically significant differences between the different patient age groups. Overall speech success was achieved in 69.4% of patients. Patients in group A achieved 78.6% speech success, patients in group B achieved 78.3% speech success, and patients in group C achieved 56% speech success, with no statistically significant differences being shown regarding speech success between the different patient age groups (P > 0.05).

Conclusions
Regardless of age, palatal lengthening via double opposing buccinator myomucosal flaps similarly improves speech outcomes.
The Role of the Fascia-Only Anterolateral Thigh Flap in Extremity Reconstruction
Authors: Hassan Bashar , Fairchild Berry , Grant Michael P. , Lamaris Gregory A. 
Published: March 2024

Background
Free flap selection in extremity reconstruction can be challenging. The ideal flap has to be thin and pliable to achieve optimal contour and function. We explore the role of the fascia-only anterolateral thigh (fALT) flap in extremity reconstruction.

Methods
We conducted a retrospective review of our experience using fALT-free flap for extremity reconstruction over a 2-year period. Patient demographics, mechanism of injury, flap characteristics, complications- and follow-up were recorded. Descriptive statistics were calculated.

Results
Twelve patients were included. The median (interquartile range [IQR]) age was 34 (28–52) years. One fALT flap was used for upper extremity reconstruction, while 11 flaps were used for lower extremity reconstruction (4 for lower third of the leg, 4 for dorsum of foot, and 3 for heel). The median (IQR) flap surface area was 90 (63–120) cm2 and time from injury to reconstruction was 10 (6–16) days. The postoperative course was uneventful for all flaps except for 1 flap failure and 1 delayed healing. The median (IQR) follow-up was 2 (1–4) months. In all cases, durable soft tissue reconstruction was achieved with no need for revisions.

Conclusions
The fALT-free flap can be successfully used in extremity reconstruction. The ALT fascia has robust perfusion that allows for the harvest of a large flap that can be surfaced with a split thickness skin graft. Its thin pliable tissue provides excellent contour for the hand, distal leg, and foot that does not require future thinning, optimizing the cosmetic and functional result.
Diagnostic approach to penetrating neck trauma: What you need to know
Authors: Siletz Anaar , Inaba Kenji 
Published: March 2024

ABSTRACTDiagnostic evaluation of penetrating neck trauma has evolved considerably over the last several decades. The contemporary approach to these injuries is based primarily on clinical signs of injury and multidetector computed tomographic angiography. The neck is evaluated as a unit, rather than relying on the surface anatomy zones in which external injuries are seen to guide the workup of internal injuries. This “no-zone” approach safely spares many patients from negative explorations and unnecessary invasive tests. The purpose of this review is to describe an evidence-based approach to the diagnostic evaluation of penetrating neck trauma, including indications for adjunctive testing beyond physical examination and multidetector computed tomographic angiography.LEVEL OF EVIDENCELiterature Synthesis and Expert Opinion; Level V.
American Association for the Surgery of Trauma/American College of Surgeons Committee on trauma clinical protocol for post-discharge venous thromboembolism prophylaxis after trauma
Authors: Berndtson Allison E. , Cross Alisa , Yorkgitis Brian K. , Kennedy Ryan , Kochuba Matthew P. , Tignanelli Christopher , Tominaga Gail T. , Jacobs David G. , Ashley Dennis W. , Ley Eric J. , Napolitano Lena , Costantini Todd W. 
Published: March 2024

AbstractTrauma patients are at an elevated risk for developing venous thromboembolism (VTE), which includes pulmonary embolism and deep vein thrombosis. In the inpatient setting, prompt pharmacologic prophylaxis is utilized to prevent VTE. For patients with lower extremity fractures or limited mobility, VTE risk does not return to baseline levels post-discharge. Currently, there are limited data to guide post-discharge VTE prophylaxis in trauma patients. The goal of these post-discharge VTE prophylaxis guidelines are to identify patients at the highest risk of developing VTE after discharge and to offer pharmacologic prophylaxis strategies to limit this risk.