bluuebunny/crossref_metadata_2025_split huggingface dataset:
Analysis of the Therapeutic Efficacy of Arthroscopic Repair of the Subscapularis Tendon Combined with Coracoplasty
Authors: Zheng Hanlin , Liu Yulong , Tu Bizhi , Chen Guang , Ning Rende 
Published: April 2024

Abstract

Objective: The purpose of this study was to analyze the outcomes of arthroscopic subscapularis tendon repair combined with coracoplasty in the treatment.
Methods: The study included 80 patients (46 males, 34 females; age range 33 to 73 years old), they underwent arthroscopic repair for subscapularis tear (typeⅠ，typeⅡ and type Ⅲ) presenting with symptoms of anterior shoulder pain and tenderness. Subcoracoid impingement was defined as a coracohumeral distance of less than 6 mm on the preoperative magnetic resonance image, and the follow-up was at least two years. Patients included two groups: Group A underwent coracoplasty, while Group B did not. The postoperative functional results of the two groups were compared and analyzed. The prognosis of patients was evaluated preoperatively and postoperatively by the University of California Los Angeles (UCLA) shoulder score，American Shoulder and Elbow Surgeons（ASES) shoulder score and Visual Analog Scale（VAS）pain score.
Results: Postoperative observations revealed successful primary wound healing among all patients, without any systemic or localized shoulder joint infections or brachial plexus nerve injuries. Both groups exhibited a notable enhancement in overall functional outcomes following surgical intervention. At the 24-month postoperative follow-up, all assessed parameters in both groups showed substantial improvement compared to the preoperative values (P<0.05). The functional scores demonstrated a noteworthy increase in both groups after surgery compared to the preoperative values (p<0.01). When comparing two groups, the p-values for all indicators, except for the forward flexion range of motion, were less than 0.01. The statistical results indicated that patients in Group A had better recovery outcomes than those in Group B, except for forward flexion range of motion.
Conclusion: The findings suggested that subcoracoid impingement syndrome could potentially serve as a significant precursor to subscapularis tendon injuries.It is worth noting that the combined approach of subscapularis tendon repair and coracoplasty demonstrated superior therapeutic efficacy compared to isolated subscapularis tendon repair, when subscapularis tendon injuries were associated with subcoracoid impingement.
Hyperoxaemia in Acute Trauma is Common and Associated with a Longer Hospital Stay – a Multicentre Retrospective Cohort Study
Authors: Iten Manuela , Pietsch Urs , Knapp Juergen , Jakob Dominik , Kummrey Gerd , Maschmann Christian , Steinmetz Jacob , Arleth Tobias , Mueller Martin , Hautz Wolf 
Published: April 2024

Abstract

Background: Trauma poses a significant global health challenge. Despite advancements in the management of severely injured patients, (poly)trauma continues to be a primary contributor to morbidity and mortality worldwide. In the context of trauma resuscitation, supplemental oxygen is commonly administered generously as suggested by guidelines. Yet, it remains uncertain whether the trauma population might derive advantages from a more conservative approach to supplemental oxygen.
Methods: In this retrospective cohort study from two Swiss trauma centers, severely injured adult (>16 years) trauma patients with an Injury Severity Score (ISS) ≥16 were divided into four groups according to the first blood gas analysis taken: hypoxaemia (PaO2 <80mmHg), normoxaemia (PaO2 80-120mmHg), which served as reference, moderate hyperoxaemia (PaO2 >120-300mmHg) and severe hyperoxaemia (PaO2 >300mmHg). The primary outcome was 28-day mortality. Length of hospital stay (LOS) and length of intensive care unit stay (LOS-ICU) were analyzed as secondary outcomes.
Results: Of 1,189 trauma patients, 41.3% had hyperoxaemia (18.8% with severe hyperoxaemia) and 19.3% had hypoxaemia. No difference was found for 28-day mortality (hypoxaemia: 15.7%, normoxaemia: 14.1%, hyperoxaemia: 13.8%, severe hyperoxaemia: 16.0%, p = 0.846). Patients with severe hyperoxaemia had a significant prolonged LOS (median 12.5 [IQR 7-18.5] days vs. 10 [7-17], p = 0.040) and extended LOS-ICU (3.8 [1.8-9] vs. 2 [1-5] days, p=0.149) compared to normoxaemic patients. In multivariable analysis, oxygen group was not associated with the primary ouerstcome 28-day mortality or LOS-ICU. Severe hyperoxaemia patients had a tendency towards longer hospital stay (adjusted coefficient 2.23 days [95% CI: -0.32; 4.79], p=0.087).
Conclusion: Hyperoxaemia was not associated with an increased 28-day mortality when compared to normoxaemia. However, both moderate and severe hyperoxaemia is frequently observed in trauma patients, and the presence of severe hyperoxaemia showed a tendency with extended hospital stay compared to normoxaemia patients. Robust randomized controlled trials are imperative to thoroughly evaluate the potential correlation between hyperoxaemia and outcomes in trauma patients.
Trial Registration: Retrospectively registered
Interventions can improve patient experienced quality of care in transitions between healthcare settings: A scoping review.
Authors: Hindsbak Natasia , Morsø Lars , Hvidtjørn Dorte , Walløe Sisse 
Published: April 2024

Abstract

Transitions in healthcare settings can be a challenge for patients and they express a need for guidance and support to cope with these transitions. The aim of this scoping review was to investigate if interventions can improve patients’ experiences when transitioning between healthcare settings. This review was conducted following the Johanna Briggs Institute’s methods and reported according to the PRISMA-ScR Checklist. Included articles were published and peer-reviewed, and reported qualitative and quantitative findings on patient experiences with interventions when transitioning between healthcare settings. The search was conducted in December 2021 in Medline Ovid, Embase Ovid, and Cinahl and 19 studies were included. Factors extracted from the studies were: author(s), year of publication, country of origin, study design, theoretical methods, population description, intervention, phenomena of interest(s), and key findings. There has been an increase in published studies on the subject in the last few years, and most of the included studies originated from Western countries. Most studies were quantitative, primarily RCTs, and the theoretical methods were thus mainly statistical analysis. The study populations were found to be heterogeneous. The interventions were categorized: care coordinator, program, integrated care, coaching, discharge care plan, and miscellaneous interventions. Overall interventions were found to improve the patient experience. Re-centralization of healthcare has increased the number of transitions, and patients express that the coordination of healthcare transitions can be improved. This review’s findings should be used alongside other research on interventions’ effect on factors like hospital readmissions and mortality to determine the optimal intervention to implement.
Development of a tool outline measurement system by using vision-based algorithms
Authors: Kim Sumin , Jung Minsu , Park Jong-kyu 
Published: April 2024

Abstract

Current domestic reground tool measurement methods either rely on the operator's experience or involve analyzing signals from multiple sensors to determine the tool condition. Despite the availability of numerous measurement techniques, accurately determining the condition of reground tools' condition remains challenging due to the varying time, equipment requirements, and the inherent difficulty in analyzing complex signals. Consequently, collecting comprehensive tool data becomes imperative. This study introduces a novel approach by developing a method for measuring the outer edge of tools, enabling precise condition assessment through a vision-based measurement system. This system not only aims to mitigate the errors commonly associated with manual measurements in the manufacturing sector but also seeks to enhance the process analysis efficiency. By doing so, it aims to significantly decrease the rejection rates of tool measurements and streamline the analysis process, potentially extending tool life and improving performance management. This method promises to contribute to more sustainable manufacturing practices by optimizing tool usage and reducing waste.
Immune cells and blood lipids mediation: a Mendelian randomization study on metabolic dysfunction-associated fatty liver disease
Authors: Shen Qi-En , Liu Zhening , Huang Hangkai , Liang Yujie , Chen Minjie , Xu Chengfu 
Published: April 2024

Abstract

Background: The current understanding of the relationship between immune cells and metabolic dysfunction-associated fatty liver disease (MAFLD) is limited. The purpose of this study was to examine the causal role played by immune cells in MAFLD.
Methods:
To investigate the causal association between immune cells and MAFLD, two-sample Mendelian randomization (MR) studies were conducted. Summary statistics were obtained from genome-wide association studies (GWASs) of 731 immune traits (4 types and 7 panels) and from the two largest meta-GWASs of MAFLD. Thorough reverse and sensitivity analyses were utilized to validate the strength of the findings. Mediation MR analyses were performed to investigate the potential mediating effects of various MAFLD risk factors, such as blood lipids, on the relationship between immune traits and MAFLD.
Results:
We found that genetically predicted higher CD25 expression on IgD- CD38dim B cells (OR = 0.93, 95% CI = 0.88–0.99) was associated with a lower risk of developing MAFLD. The proportion of genetically predicted CD25 on IgD- CD38dim B cells mediated by high-density lipoprotein cholesterol (HDL-C) was 2.21% and that on Apolipoprotein A1 is 1.91%. During the reverse analysis of the significant impact of NAFLD on immunophenotype, the leukocyte AC TBNK (OR = 1.66, 95% CI = 1.22 ~ 2.27) was identified.
Conclusion: Our study provides genetic evidence regarding the role of CD25 on IgD- CD38dim B cells in MAFLD mediated by blood lipids and supports a causal association between various immune cells and MAFLD.
Menstrual Practice Needs among College going Women in Coimbatore district, India: An analytical cross-sectional study
Authors: Ramya V , Kumar Mohan , Jeevithan S , Seetharaman N , Mahanshetty Sushmitha , Dhandapani Srihari , Aparnavi P , Durairaj T , Ramesh M 
Published: April 2024

Abstract
Background: In India, twenty-five percent of women who menstruate are unable to utilize sanitary methods, and even among those who have access, there are multiple obstacles to achieving proper menstrual hygiene management. The consequences of inadequate menstrual health affect a girl's school participation and extend to her empowerment, overall well-being, and even survival.
Objectives: To estimate the prevalence of unmet menstrual practice needs and its determinants among college going women in Coimbatore district, India.
Methodology: A questionnaire based analytical cross-sectional study was conducted among 3144 college going women from October 2022 to January 2023. Menstrual Practice Needs Scale (MPNS-36) was used to collect data regarding the unmet needs and their mean scores were compared across socio-demographic variables, menstrual knowledge, and the choice of hygiene material.
Results: The mean (SD) age of the study population was 19.3 (1.8) years. The prevalence of unmet menstrual practice needs was 62.8% with a mean (SD) MPNS score of 1.8 (0.4). The total MPNS score was low for those currently residing in rural or having a rural hometown. The unmet need was better for those residing in-campus of the educational institute and having educated parents. The socioeconomic class and presence of a personal income also influenced the total MPNS scores significantly (p<0.05). Menstrual talks with friends before puberty and with friends and family after puberty improved the MPNS scores. Regarding menstrual hygiene methods, modern menstrual methods (MMM), disposable and bio-degradable materials had a lower unmet need. Marital status, freedom to manage expenses, pre-pubertal menstrual talks with family, and total number of family members did not influence the scores of MPNS. Multivariate regression analysis showed that maternal education, menstrual talks with family after puberty, and type of menstrual hygiene method including its disposability were independent predictors of total MPNS scores.
Conclusion: Addressing unmet menstrual practice needs among college-going women in Coimbatore district necessitates a multifaceted approach encompassing education, access to affordable and sustainable menstrual products, and destigmatization efforts.
Oxford-Palestine (OxPal) partnership: evaluation of an online medical research fellowship aiming to build local research capacity
Authors: Saini Kirandeep , Jurdon Rebecca , Conway-Jones Rebecca , Penfold Rose , Alser Osaid 
Published: April 2024

Abstract
Background
Innovative methods of delivering medical education across borders have the potential to further the development of healthcare capacity in austere environments. Medical students and doctors in the occupied Palestinian territory (oPt) face barriers to their education; whilst geographical, technological, and financial obstacles have limited the ability of institutions in high-income countries to share effective educational resources. We aimed to investigate the effectiveness of an international partnership in meeting the expressed educational needs of Palestinian medical students and doctors, through a locally tailored research training online course.
Methods
A needs assessment was used to guide the design, format, topic and content of an interactive lecture course. It was delivered to medical students in the oPt by clinicians & scientists from the U.K. and U.S.A. through an online lecture platform. The programme was evaluated through questionnaires and focus groups.
Results
We found students’ greatest expressed need was for supplementary teaching on medical research. Students perceived interactive online distance-teaching, delivered by utilising excess tutor capacity at educational-resource rich institutions, as equal (22%, n = 20) or superior (76%, n=71) to local in-person alternatives.
Conclusions
We demonstrate a low-cost, replicable method of supplementing medical education, generating engagement and building healthcare research capacity in an austere environment. Other institutions can rapidly deploy this model to upscale outreach efforts and improve global medical education.
A diagnostic model for hydraulic fracture in naturally fractured reservoir utilising water-hammer signal
Authors: Deng Shijie , Yi Liangping , Li Xiaogang , Yang Zhaozhong , Zhang Nanqiao 
Published: April 2024

Abstract

Diagnostic technique for hydraulic fracture based on the water-hammer pressure have been gradually highlighted owing to their cost effectiveness and simplicity. The present diagnostic models overlook the effects of fluid leak-off and natural fracture, and it is limited in naturally fractured reservoir. In this study, the location and number of hydraulic fractures are first obtained through the enhancement and cepstrum processing of a water-hammer signal. Subsequently, the water-hammer pressure within the wellbore is calculated by solving the continuity and momentum equations for the fluid. Wellbore and hydraulic fractures are considered as a hydraulic system. To estimate the fracture dimension, flow boundary conditions are imposed to the fluid leak-off, interactions between natural and hydraulic fractures, and multifracture stress shadows. Based on the results, (1) the fracturing shut-in method can be appropriately adjusted to avoid large pressure pulsations, which damage well integrity, and to obtain a clear water-hammer signal for fracture diagnosis. (2) As the perforation cluster spacing increases, the fractures on both sides first decrease and then increase, whereas the centre fracture increases consistently. (3) Natural fractures reduce the hydraulic fracture dimensions but facilitate the creation of complex fracture networks; however, this complexity cannot be increased indefinitely. (4) The minimum horizontal stress decreases the fracture dimension and a greater difference in the horizontal stress renders it easier for hydraulic fractures to cross natural fractures to create larger dimensions. (5) The field study demonstrates the practicality of our model, and optimisation measures can be recommended based on the diagnostic results.
First-line hepatic arterial infusion chemotherapy plus lenvatinib and PD-(L)1 inhibitors versus systemic chemotherapy alone or with PD-(L)1 inhibitors in unresectable intrahepatic cholangiocarcinoma: a real-world study
Authors: Lin Yan-Song , Li Shuo , Yang Xia , Guo Rong-Ping , Huang Yu-Hua , Bai Kun-Hao , Weng Jun , Yun Jing-Ping 
Published: April 2024

Abstract
Purpose
Limited treatment options exist for unresectable intrahepatic cholangiocarcinoma (ICC), with systemic chemotherapy (SC) serving as the primary approach. This study aimed to assess the effectiveness of first-line hepatic arterial infusion chemotherapy (HAIC) in combination with lenvatinib and PD-(L)1 inhibitors (HLP) compared to SC combined with PD-(L)1 inhibitors (SCP) or SC alone in treating unresectable ICC.
Methods
Patient with unresectable ICC who underwent first-line treatment with HLP, SCP or SC from January 2016 to December 2022 were retrospectively analyzed. The study evaluated and compared efficacy and safety outcomes across the three treatment groups.
Results
The study comprised 42, 49, and 50 patients in the HLP, SCP, and SC groups, respectively. Median progression-free survival (PFS) times were 30.0, 10.2, and 6.5 months for HLP, SCP, and SC groups. While the SC group had a median overall survival (OS) time of 21.8 months, the HLP and SCP groups hadn't reached median OS. The HLP group demonstrated significantly superior PFS and OS compared to the others. Moreover, the HLP group exhibited the highest objective response rate (ORR) at 50.0% and the highest disease control rate (DCR) at 88.1%, surpassing the SC group (ORR, 6.0%; DCR, 52.0%) and SCP group (ORR, 18.4%; DCR, 73.5%) (p < 0.05). Generally, the HLP group reported fewer grades 3–4 adverse events (AEs) compared with others.
Conclusion
In contrast to systemic chemotherapy with or without PD-(L)1 inhibitors, the triple combination therapy incorporating HAIC, lenvatinib, and PD-(L)1 inhibitors showcased favorable survival benefits and manageable adverse events for unresectable ICC.
Research on Sub-Pixel Accuracy Flange Disk Dimension Measurement Based on Machine Vision
Authors: Guo Jun , Yang Yang , Chen Yuxin 
Published: April 2024

Abstract

Addressing the inefficiencies and inaccuracies inherent in manual measurements of flange disk dimensions, we propose a machine vision-based method for sub-pixel measurement, alongside a dedicated visual measurement system. This system utilizes a CCD camera, calibrated via PyCharm software, to capture images of the flange disk. These images undergo preprocessing—conversion to grayscale, filtering, noise reduction, and binary segmentation—to delineate the flange disk area for further analysis. For edge detection, an improved Canny adaptive threshold selection algorithm is employed. Additionally, we introduce a new edge judgment criterion based on the Zernike algorithm, which, in conjunction with the advanced Canny operator for initial positioning, allows our refined Zernike matrix algorithm to accurately identify the flange disk edge with sub-pixel precision. The least squares fitting algorithm is then applied to determine the flange disk's outer and inner diameters accurately. A comparative analysis of experimental results demonstrates that our enhanced algorithm significantly reduces relative errors compared to both its predecessor and manual measurements. Importantly, the measurements obtained with the improved algorithm closely match manual measurements and are markedly more accurate than those achieved with the traditional Zernike matrix algorithm. This level of precision ensures that our measurement method meets the high accuracy requirements of industrial parts manufacturing.
Assessing reliability and validity of the Chi nese version of the Depression Change Exp ectancy Scale and its application in college students
Authors: Li Shuoshuo , Zhou Zhongtao , Cai Fulin , Cheng Ling , Du Weina , Bai Huaiyu , Li Qingyang , Wang Wenjuan , Zhang Jing 
Published: April 2024

Abstract

Background With mental health issues getting worse, depression plays an essential role in the development of individuals. There are few measurements of depression change expectancy for college students. This study examines the applicability of the Depression Change Expectancy Scale for Adults to a sample of Chinese college students. It provides a measurement tool for depression change expectancy among Chinese college students.
Methods According to the Brislin translation model, the first draft was translated and translated into the scale. The Chinese version of the scale was formed through expert localization debugging and pre-investigation. Using the convenience sampling method, 1138 students were surveyed in several medical schools in Anhui province from September to December 2023, and 481 students with depressive symptoms or tendencies were screened out for the reliability and validity analysis of the change in depression expectation scale.
Results: The scale has a good single-factor structure (CMIN/DF = 2.604, CFI = 0.973, TLI = 0.970, GFI = 0.912, NFI = 0.958, RMSEA = 0.058). The content validity (S-CVI) is 0.898, and each item's content validity (I-CVI) is 0.830 ~ 1.000. The coherence within The reliability analysis scale's Cronbach's coefficient is 0.910, and each dimension is 0.888–0.980. the test-retest reliability is 0.985, and each dimension's test-retest reliability is 0.982–0.985.
Conclusion According to this study, the Chinese version of the DCES has excellent validity and reliability. It may be used as a tool for evaluation to determine how patients' depression is changing over time.
Castor oil based biolubricant: optimization of the synthesis process and investigating its effects on two-stroke engine parameters
Authors: Soufi Masoud Dehghani , Sabzimaleki Mohammadreza , Khashehchi Morteza , Ghobadian Barat , Rahmanivahid Pooyan , Heidari Milad 
Published: April 2024

Abstract
Biolubricants are new generation of lubricants, which are vegetable based, renewable and eco-friendly. In this study, trimethylolpropane ester (biolubricant) was synthesized from castor oil methyl ester through transesterification reaction. The reaction was optimized using response surface methodology (RSM) and the optimal parameters were obtained for maximizing the reaction yield. In continuation, the physicochemical specifications of the purified product was measured and met the requirements of ISO-VG lubricant standard. The castor oil based biolubricant then was mixed with gasoline with 1:10 volumetric ratio and was used in a 200 cc two stroke petrol engine to investigate its effects on the performance and exhaust emissions of the engine. The optimal conditions for biolubricant synthesis reaction were obtained as the methyl ester to TMP molar ratio of 4.78:1, reaction temperature of 139.9°C, and the catalyst (potassium carbonate) concentration of 1.4%. In this optimum condition, the reaction yield was obtained as 96.13%. The engine tests results showed that the engine power and torque increases by 2.89% and 1.97%, respectively using castor oil based biolubricant compared with SAE10 oil. Moreover, the brake specific fuel consumption (BSFC) of the engine fuelled with biolubricant had a 4.6% decrease compared to the commercial two-stroke engine oil. It was also found that the produced castor biolubricant can significantly decrease the carbon monoxide and unburned hydrocarbons emissions of the engine by nearly 153% and 59%, respectively in comparison with SAE10 oil.