bluuebunny/crossref_metadata_2025_split huggingface dataset:
Immersive virtual reality-based learning as a supplement for biomedical engineering labs: challenges faced and lessons learned
Authors: Tandon Ishita , Maldonado Vitali , Wilkerson Megan , Walls Amanda , Rao Raj R. , Elsaadany Mostafa 
Published: March 2024

IntroductionImmersive virtual reality (VR) based laboratory demonstrations have been gaining traction in STEM education as they can provide virtual hands-on experience. VR can also facilitate experiential and visual learning and enhanced retention. However, several optimizations of the implementation, in-depth analyses of advantages and trade-offs of the technology, and assessment of receptivity of modern techniques in STEM education are required to ensure better utilization of VR-based labs.MethodsIn this study, we developed VR-based demonstrations for a biomolecular engineering laboratory and assessed their effectiveness using surveys containing free responses and 5-point Likert scale-based questions. Insta360 Pro2 camera and Meta Quest 2 headsets were used in combination with an in-person lab. A cohort of 53 students watched the experimental demonstration on VR headsets in the lab after a brief lab overview in person and then performed the experiments in the lab.ResultsOnly 28.29% of students reported experiencing some form of discomfort after using the advanced VR equipment as opposed to 63.63% of students from the previous cohort. About 40% of the students reported that VR eliminated or reduced auditory and visual distractions from the environment, the length of the videos was appropriate, and they received enough information to understand the tasks.DiscussionThe traditional lab method was found to be more suitable for explaining background information and lab concepts while the VR was found to be suitable for demonstrating lab procedures and tasks. Analyzing open-ended questions revealed several factors and recommendations to overcome the potential challenges and pitfalls of integrating VR with traditional modes of learning. This study provides key insights to help optimize the implementation of immersive VR to effectively supplement in-person learning experiences.
Association between cognitive function and body composition in older adults: data from NHANES (1999–2002)
Authors: Chen Lianghua , Zou Liling , Chen Jingwen , Wang Yixiao , Liu Dandan , Yin Lianjun , Chen Junqi , Li Haihong 
Published: March 2024

AimTo investigate the association between cognitive function and body composition in older adults.MethodsWe collected data on 2080 older adults (&gt;60 years of age) from the National Health and Nutrition Examination Survey (NHANES) for the years 1999–2000 and 2001–2002. Candidate variables included: demographic data (sex, age, race, education level, marital status, poverty-to-income ratio), alcohol consumption, cardiovascular disease, diabetes, osteoporosis, total bone mineral density, and total fat mass. A logistic regression model was established to analyze the association between cognitive function and body composition in older adults. In addition, stratified logics regression analysis was performed by sex and age.ResultsBone mineral density significantly affects cognitive function in older adults (p&lt;0.01). When examining the data according to sex, this correlation is present for women (p &lt; 0.01). For men, though, it is not significant (p = 0.081). Stratified by age, total bone mineral density was significantly correlated with cognitive function in 60–70 and 70–80 years old people, but not in older adults older than 80 years(for 60–70 years old, p = 0.019; for 70–80 years old, p = 0.022). There was no significant correlation between total bone mineral density and cognitive function (p = 0.575).ConclusionThe decrease of total bone mineral density was significantly correlated with cognitive decline in the older adults, especially among women and older people in the 60 to 80 age group. There was no connection between total fat mass, total percent fat, total lean mass, appendicular lean mass, appendicular lean mass /BMI and cognitive function in the older adults.
Electrophysiological analysis of signal detection outcomes emphasizes the role of decisional factors in recognition memory
Authors: Schneider Stephan , Coll Sélim Yahia , Schnider Armin , Ptak Radek 
Published: March 2024

IntroductionEvent-related potential (ERP) studies have identified two time windows associated with recognition memory and interpreted them as reflecting two processes: familiarity and recollection. However, using relatively simple stimuli and achieving high recognition rates, most studies focused on hits and correct rejections. This leaves out some information (misses and false alarms) that according to Signal Detection Theory (SDT) is necessary to understand signal processing.MethodsWe used a difficult visual recognition task with colored pictures of different categories to obtain enough of the four possible SDT outcomes and analyzed them with modern ERP methods.ResultsNon-parametric analysis of these outcomes identified a single time window (470 to 670 ms) which reflected activity within fronto-central and posterior-left clusters of electrodes, indicating differential processing. The posterior-left cluster significantly distinguished all STD outcomes. The fronto-central cluster only distinguished ERPs according to the subject’s response: yes vs. no. Additionally, only electrophysiological activity within the posterior-left cluster correlated with the discrimination index (d’).DiscussionWe show that when all SDT outcomes are examined, ERPs of recognition memory reflect a single-time window that may reveal a bottom-up factor discriminating the history of items (i.e. memory strength), as well as a top-down factor indicating participants’ decision.
The relationship between mindfulness and suboptimal health status: a chain/serial mediation model
Authors: Liang Jingyue , Zhang Xiaoshuo , Wang Yuzheng 
Published: March 2024

BackgroundSuboptimal health status (SHS) represents a third state between health and disease and often progresses into chronic conditions, negatively impacting an individual’s well-being. Studies have shown that mindfulness has a beneficial effect on various SHS symptoms. This study aims to explore the influence of mindfulness on SHS and its underlying mechanisms, with a particular focus on examining the mediating roles of stress and social support.MethodsA total of 173 healthy Chinese college or graduate students, with an average age of 21.85 years, participated in this study. Measurements were taken using the Five Factor Mindfulness Questionnaire, the Sub-Health Measurement Scale, the Perceived Stress Scale, and a self-constructed scale that included demographic information. The PROCESS plugin for SPSS was used to assess mediating effects.ResultsSignificant correlations were found among SHS, social support, mindfulness, and perceived stress (|r| = 0.38–0.85, p &lt; 0.01). Specifically, mindfulness showed a significant positive correlation with SHS and social support (r = 0.38–0.77), while perceived stress was significantly negatively correlated with mindfulness, social support, and SHS (|r| = 0.45–0.85). Perceived social support was positively associated with SHS (r = 0.65). Furthermore, social support and perceived stress partially mediated the influence of mindfulness on SHS. Additionally, a sequential mediation effect of perceived social support and stress in the relationship between mindfulness and SHS was supported.ConclusionThe cultivation of trait mindfulness may be advantageous for individuals’ sub-health. Perceived social support and perceived stress are important underlying mechanisms contributing to this effect.
Middle-aged and older adults in Aids village: a mixed methods study on talking about death and well-being promotion based on social support theory
Authors: Zhang Lin 
Published: March 2024

IntroductionWill about talking about death bring well-being? This study aims to explore the impact of talking about death on the subjective well-being of the rural middle-aged and older adults in China’s “Aids village” from five dimensions: the way of talking about death, the attitude towards talking about death, the objects of talking about death with, the frequency of talking about death and the content of the death talk, and investigate whether social support played a mediating role during this process.MethodsA field survey and in-depth interviews were conducted in Wen Lou village (a famous Chinese “Aids village”), and valid questionnaires were completed by the HIV/Aids-affected middle-aged and older adults. A series of linear regression analyses were conducted to detect whether the way of talking about death, the attitude towards talking about death, the objects of talking about death with, the frequency of talking about death and the content of the death talk predict the subjective well-being of the HIV/Aids-affected middle-aged and older adults. An empirical test for mediation effect was performed to examine whether social support played a mediating role during the process.ResultsIt was found that the more frequent the middle-aged and older adults talk about death, the higher level of their subjective well-being is (ΔR2 = 0.056, 0.05 &lt; p &lt; 0.10), and during which process social support played a mediating role.DiscussionThe author believes that using “talking about death” as a kind of medical intervention, carrying out corresponding life education and death education, and developing a suitable hospice care model, may be a valuable way for the HIV/Aids-affected middle-aged and older adults in the rural area.
Association between cardiovascular risk and maternal perception of BMI in Peruvian schoolchildren
Authors: Mamani Margoth Ccari , Martínez Jhosset Flores , Llico Raquel Chilón , Sairitupa-Sanchez Liset Z. , Morales-García Sandra B. , Rivera-Lozada Oriana , Morales-García Wilter C. 
Published: March 2024

IntroductionIn the modern era, the maternal perception of children’s nutritional status has emerged as a critical area of study, given its potential influence on nutritional interventions and long-term child health. The relationship between this perception and children’s Body Mass Index (BMI) by age is particularly intriguing, as it may reveal discrepancies between perception and reality.ObjectiveThe aim of this study was to evaluate Peruvian mothers’ perception of their children’s Body Mass Index (BMI) in relation to age and to determine how this perception associates with the children’s cardiovascular risk. The study also analyzed sociodemographic factors that might influence this perception.MethodsThe study included 130 mothers of schoolchildren aged 5 to 11 from a school in Lima. Mothers’ perceptions of their children’s weight were assessed using pictograms, and sociodemographic characteristics were collected through a questionnaire. Weight and height measurements were taken to calculate BMI, and waist circumference was measured to classify cardiovascular risk.ResultsA total of 57.4% of the schoolchildren presented with excess malnutrition, and 51.5% of the mothers incorrectly classified the actual BMI/Age of their children (kappa 0.11; p ≤ 0.05). Additionally, it was found that the schoolchild’s age is associated with the mother’s failure to accurately perceive her child’s weight (OR 1.59). Lastly, there was a significant association between maternal perception and cardiovascular risk (p ≤ 0.05).ConclusionThere is a significant discrepancy between maternal perception and the actual nutritional status of children, which can increase cardiovascular risk. It is necessary to implement intervention and education strategies targeted at parents to enhance the recognition and management of childhood overweight and obesity.
Approximation to the economic cost of healthcare for hypertensive patients diagnosed with COVID-19
Authors: Calderón-Moreno Jesús , Delgado-Rodriguez María Jesús , Juárez-Vela Raúl , Tejada-Garrido Clara Isabel , de Viñaspre-Hernández Regina Ruiz , Burgos-Esteban Amaya , Sánchez-Conde Pilar , Andreu-Fernández Vicente , Gea-Caballero Vicente , Santos-Sanchez Jose Angel , Quintana-Diaz Manuel , Andrés-Esteban Eva María 
Published: March 2024

IntroductionMany researchers have focused their studies on hypertension due to its over-representation among COVID-19 patients. Both retrospective and observational studies conducted close to the Wuhan area have reported that hypertension is the most common comorbidity observed in patients affected by COVID-19.ObjectiveOur objective is that patients with arterial hypertension have a worse prognosis in terms of evolution leading to higher costs.MethodsA retrospective cross-sectional study was conducted. A total of 3,581 patients from La Paz University Hospital (LPUH) during the period between 15 July 2020 and 31 July 2020 were included in this study.ResultsIt should be noted that 40.71% of the patients were hypertensive. As expected, hypertension was associated with men, among whom we observed a higher prevalence and a higher age (median age of 77 years (IQI: 65–85) versus 52 years (IQI: 37–64), p-value &lt; 0.001). Hypertensive patients had a higher prevalence of dyspnea (52.14% vs. 47.15%, p-value = 0.004) and altered awareness (14.89% vs. 4.30%, p-value &lt;0.001). The non-parametric Kaplan–Meier curve estimates the survival of patients in the two study groups. We can see how patients with hypertension have a higher associated mortality, with the difference being statistically significant, p-value (log-rank) = 0.004. Only for the appearance of complications during hospitalization, the group of hypertensive patients reached the figure of €1,355,901.71 compared to the total of 421,403.48 € for normotensive patients.ConclusionOur study shows the worse clinical evolution of patients with COVID-19 in terms of associated morbidity and mortality. It also shows that the cost of managing patients with hypertension is greater than that of managing normotensive patients.
A hub and spoke model to supply the Sicilian neurorehabilitation demand: effects on hospitalization rates and patient mobility
Authors: Ielo Augusto , Quartarone Angelo , Calabrò Rocco Salvatore , De Cola Maria Cristina 
Published: March 2024

IntroductionCerebrovascular diseases in Sicily have led to high mortality and healthcare challenges, with a notable gap between healthcare demand and supply. The mobility of patients seeking care, both within and outside Sicily, has economic and organizational impacts on the healthcare system. The Hub and Spoke model implemented by the IRCCS Centro Neurolesi “Bonino-Pulejo” of Messina aims to distribute advanced neurorehabilitation services throughout Sicily, potentially reducing health mobility and improving service accessibility.MethodsThe evaluation was based on calculating hospitalization rates, examining patient mobility across Sicilian provinces, and assessing the financial implications of neurorehabilitation admissions. Data from 2016 to 2018, covering the period before and after the implementation of the Hub and Spoke network, were analyzed to understand the changes brought about by this model.ResultsThe analysis revealed a significant increase in hospitalization rates for neurorehabilitation in the Sicilian provinces where spokes were established. This increase coincided with a marked decrease in interregional health mobility, indicating that patients were able to receive high-quality care closer to their residences. Furthermore, there was a decrease in both intra-regional and inter-regional escape rates in provinces within the Hub and Spoke network, demonstrating the network’s efficacy in improving accessibility and quality of healthcare services.DiscussionThe implementation of the Hub and Spoke network substantially improved neurorehabilitation healthcare in Sicily, enhancing both accessibility and quality of care for patients. The network’s establishment led to a more efficient utilization of healthcare resources and balanced distribution of services. These advancements are vital steps toward equitable and effective healthcare delivery in Sicily.
Factors associated with the worsening of COVID-19 symptoms among cohorts in community- or home-isolation care in southern Thailand
Authors: Sila Thanit , Suriyaamorn Wisanuwee , Toh Chanavee , Rajborirug Songyos , Surasombatpattana Smonrapat , Thongsuksai Paramee , Kongkamol Chanon , Chusri Sarunyou , Sornsenee Phoomjai , Wuthisuthimethawee Prasit , Chaowanawong Raya , Sangkhathat Surasak , Ingviya Thammasin 
Published: March 2024

IntroductionThis study aimed to investigate factors associated with time-to-referral due to worsening symptoms in patients with laboratory-confirmed COVID-19 in southern Thailand. While underlying diseases have been evaluated to assess COVID-19 severity, the influence of vaccinations and treatments is also crucial.MethodsA cohort of 8,638 patients quarantined in home or community isolation with laboratory-confirmed COVID-19 was analyzed. Survival analysis and the Cox proportional hazard ratio were employed to assess factors influencing time-toreferral.ResultsAge ≥ 60 years, neurologic disorders, cardiovascular disease, and human immunodeficiency virus infection were identified as significant risk factors for severe COVID-19 referral. Patients who received full- or booster-dose vaccinations had a lower risk of experiencing severe symptoms compared to unvaccinated patients. Notably, individuals vaccinated during the Omicron-dominant period had a substantially lower time-to-referral than those unvaccinated during the Delta-dominant period. Moreover, patients vaccinated between 1 and 6 months prior to infection had a significantly lower risk of time-to-referral than the reference group.DiscussionThese findings demonstrate early intervention in high-risk COVID-19 patients and the importance of vaccination efficacy to reduce symptom severity. The study provides valuable insights for guiding future epidemic management strategies and optimising patient care during infectious disease outbreaks.
Pengaruh Rasio Keuangan terhadap Harga Saham Pada Perusahaan Food and Beverages yang terdaftar di Bursa Efek Indonesia Tahun 2017-2021
Authors: Ali  Taupan Muhammad 
Published: March 2024

Abstrak
Penelitian Ini Bertujuan Untuk Mengetahui Bagaimana Pengaruh NPM, ROA, ROE, CR, DAR Dan DER Terhadap Harga Saham Pada Perusahaan Perusahaan Food And Beverages Yang Terdaftar Di Bursa Efek Indonesia Tahun 2017 -2021. Jenis penelitian yang digunakan dalam penelitian ini adalah penelitian kuantitatif. Dilihat dari sifatnya penelitian ini bersifat deskriptif analisis. Populasi dalam penelitian ini terdiri dari semua perusahaan manufaktur sub sebktor Food and beverages yang terdaftar di Bursa Efek Indonesia (BEI) selama periode 2017 – 2021 yaitu sebanyak 30 perusahaan. Teknik sampling pada penelitian ini menggunakan Teknik purposive sampling dengan toal jumlah sample sebanyak 10 perusahan. Teknik analisis data menggunaka uji asumsi klasi, uji regresi berganda dan uji hipotesis. Hasil penelitian ini adalah secara parsial Net Profit Margin, return on asset dan return on equity berpengaruh positif dan signifikan Terhadap Harga Saham Pada Perusahaan Food And Beverages Yang Terdaftar Di Bursa Efek Indonesia Tahun 2017 -2021. secara parsial current ratio, debt to asset ratio dan debt to equity ratio tidak berpengaruh positif dan tidak signifikan Terhadap Harga Saham Pada Perusahaan Food And Beverages Yang Terdaftar Di Bursa Efek Indonesia Tahun 2017 -2021. Secara simultan NPM, ROA, ROE, CR, DAR dan DER berpengaruh positif dan signifikan Terhadap Harga Saham Pada Perusahaan Food And Beverages Yang Terdaftar Di Bursa Efek Indonesia Tahun 2017 -2021. Kkoefisien determinasi (adjusted R2) yang diperoleh sebesar 0,74. Hal ini berarti 74% variabel dependent yaitu harga saham dapat dijelaskan oleh variabel independentnya yaitu net profit margin (X1), current ratio (X2), return on asset (ROA), return on equity (ROE), current ratio (CR), debt to asset ratio (DAR) dan Debt to equity ratio (DER) dan 36% lainnya dapat dijelaskan oleh variabel lain diluar penelitian ini seperti total asset turn over dan lain-lain.

Kata kunci : NPM, ROA, ROE, CR, DAR, DER
Have Courage to Use your Own Mind, with or without AI: The Relevance of Kant's Enlightenment to Higher Education in the Age of Artificial Intelligence
Authors: Watanabe Alice 
Published: March 2024

Artificial intelligence (AI) in higher education is a complex issue that can be discussed from many different perspectives. There is currently a great need for ethical discussions about the use of AI in universities. For example, educational researchers and teachers are already talking a lot about fairness, accountability, transparency, bias, autonomy, agency and inclusion of AI applications, and discussing these in terms of concrete teaching-learning settings. However, less explored are the implications of AI-enhanced teaching and learning in relation to fundamental educational ideals and goals. The article takes this research desideratum as a starting point by relating the use of AI in universities to Kant's reflections on enlightenment. The aim of this article is to theoretically analyse the compatibility of various AI tools with the ideal of maturity on an educational philosophical level and to formulate recommendations for action based on the results. Through a comprehensive literature review, the article analyses the impact of intelligent tutoring systems, ChatGPT and AI-supported research tools on students’ maturity and discusses both opportunities and challenges for higher education. The theoretical analysis shows that intelligent tutoring systems and ChatGPT threaten student maturity, while AI-supported research tools can have a positive effect. In addition, the analysis provides several recommendations that can help to minimise the risks of AI applications in terms of student maturity. The educational principle of research-based learning is of particular importance in this context, illustrating how students can learn to use AI tools responsibly and maturely. In this sense, the paper presents a theoretical study that fundamentally reflects on the maturity of students in the age of AI and thus both encourages teachers in the field of e-teaching to critically reflect on AI-based tools and provides a basis for further empirical research.
Експлікація філософських ідей дихотомії поколінь Мішеля Серра у викликах сучасної культури
Authors: Koberska Tetiana , Sarnavska Oksana 
Published: March 2024

У статті досліджується кризові аспекти дихотомії поколінь цифрового суспільства у викликах культури постмодерну. Теоретичну основу розвідки становлять культурно-антропологічні аспекти впливу інформаційних технологій на становлення та самоствердження сучасної молоді в контексті її ціннісних орієнтирів і формування на цій основі моделей поведінки. Метою роботи є міждисциплінарний аналіз проблеми розгортання життєвої ситуації молодого покоління цифрової культури, названого французьким філософом, культурологом та педагогом М. Серром як «хлопчик/дівчинка з пальчик». Окреслено розвиток теоретичного дискурсу філософських ідей М. Серра та розглянуто особливості конструювання ідентичності особистості в постмодерному цифровому комунікативному просторі. Досліджено особливості трансформації світоглядних засад молодого покоління «хлопчик/дівчинка з пальчик» у контексті аксіологічних змін. Продемонстровано значущість для української філософсько-педагогічної думки актуальності звернення до соціокультурного аналізу зарубіжних аналітиків сучасності, що дало можливість окреслити ознаки інформаційних революцій, узагальнити та актуалізувати філософську рефлексію щодо самоідентифікації особистості. Експлікувано філософський дискурс ціннісного світоглядного інструментарію розв’язання психологічних, педагогічних та освітніх кризових проблем, що поглиблює розуміння явища дихотомії поколінь та сприяє ефективній взаємодії в культурно-освітньому просторі. У статті використано методологію культурологічного підходу, що базується на ідеях А. Шюца, П. Бергера, Т. Лукмана, згідно з якими світ індивіда потрібно осмислювати в його повсякденному бутті, у зіставленні з конкретними уявленнями, цілями і поведінковими мотивами, орієнтуючись на вивчення формальних структур повсякденних людських взаємин.