bluuebunny/crossref_metadata_2025_split huggingface dataset:
Immune Cell Response of the Spleen in COVID-19
Authors: Perepelitsa S. A. 
Published: February 2024

Objective. To study the morphometric characteristics and splenic immune cell response in patients with COVID-19.Material and methods. A prospective observational study included 70 patients. Of these, 45 patients admitted to the infectious diseases hospital with Coronavirus infection caused by the SARS-CoV-2 virus diagnosis were included in the COVID-19 group, and 25 patients were included in the acute respiratory viral infection (ARVI) comparison group. Spleen linear dimensions, including length, width, and thickness were assessed using ultrasound imaging, and calculations of the spleen weight and spleen weight coeﬃcient (SWC) were obtained. Additionally leukocyte count and formula, erythrocyte sedimentation rate (ESR) were estimated, and the leukocyte index (LI) and neutrophil-to-lymphocyte ratio (NLR) were calculated.Results. Microsplenia was common in the acute period of COVID-19 with mean SWC value 1.6±0.2. In 17 (37.8%) patients the SWC varied from 1.0 to 1.5, and in 9 (20%) microsplenia was critical with SWC <1.0. Leukocyte count was lower, and ESR — higher in patients with COVID-19, compared to ARVI group (5.4±2.1×10⁹/l and 10.8±4.8×109/l, respectively P<0.00001, and ESR — 36.1±13.8 mm/h and 23.0±5.1 mm/h, respectively P=0.03). The course of COVID-19 was characterized by a slight decrease in LI — from 0.29±0.02 to 0.22±0.01 (P=0.19), and significant increase in NLR from 3.7±0.1 to 4.3±0.12 (P=0.002). Opposite trends were documented in patients with ARVI. On Day 5 since initiation of treatment LI was significantly lower in the COVID-19 vs ARVI group (0.22 [0.16; 0.39] vs. 0.48 [0.29; 0.93], P=0.003), and NLR was significantly higher (4.3 [2.5; 6.1] vs. 2.1 [0.9; 2.9], P=0.002).Conclusion. The course of coronavirus infection caused by the SARS-CoV-2 virus is characterized by significant immunological shifts. Microsplenia verified by ultrasonography stays as one of the pathognomonic signs. This phenomenon is explained by rapid «depletion» of the spleen as a secondary immune organ, and is associated with a high risk of developing acute immune deficiency.
Linking Immunological Parameters and Recovery of Patient’s Motor and Cognitive Functions In The Acute Period of Ischemic Stroke
Authors: Tynterova A. M. , Shusharina N. N. , Golubev A. M. , Moiseeva E. M. , Litvinova L. S. 
Published: February 2024

Objective. To evaluate the relationship between immunological parameters and functional outcome in patients with varying severity of ischemic stroke based on statistical methodology.Materials and methods. The prospective study included 78 patients diagnosed with ischemic stroke, who were distributed into two groups: group 1 — 38 mild stroke patients, NIHSS score < 5, group 2 — 40 moderate stroke patients, NIHSS score 5–15. Signs of stroke severity, degree of disability, cognitive decline, and activities of daily living were chosen as criteria to estimate the functional outcome by calculating the difference between the NIHSS, mRS, MoCA, and BI scales at the time of admission and on Day 12 of hospital stay. Lab tests included assessment of plasma concentrations of CXC and CC subfamilies of cytokines, interleukins and TNF-a on Day 2 of hospital stay. Machine learning algorithms, the Python programming language, the Pandas and SciPy libraries, and discriminant analysis were used for statistical processing.Results. The following parameters were found as significant: concentrations of IL-1b and MPIF-1/CCL23 for — for group 1, and concentrations of IL-16, MPIF-1/CCL23, Eotaxin-2/CCL24, Gro-a/CXCL1 and IL-8/CXCL8 for group 2 patients. Positive correlation was established between NIHSS dynamics and concentrations of TNF-a (R=0.227, P=0.001), MPIF-1/CCL23 (R=0.380, P=0.00061) and Gro-a/CXCL1 (R=0.211, P=0.00001), and between changes in mRS and concentrations of MPIF-1/CCL23 (R=0.277, P=0.00006), Gro-a/CXCL1 (R=0.211, P=0.0075) and IL-16 (R=0, 211, P=0.00001). There was a significant negative correlation between cognitive dysfunction and concentrations of Eotaxin-2/CCL24 (R=–0.378, P=0.00075), Gro-a/CXCL1 (R=–0.313, P=0.0035), and IP-10/CXCL1 (R=–0.214, P=0.00023), and between limited activities of daily living (IB) and concentrations of MPIF-1/CCL23 (R=–0.345, P=0.0024) and Gro-a/CXCL1 (R=–0.210, P=0.00001).Conclusion. Chemokines form the CC family — MPIF-1/CCL23 and Eotaxin-2/CCL24, and the CXC-Gro-a/CXCL1 and IL-16 clusters are the principal cytokines associated with the dynamics of patient’s motor and cognitive functions recovery in the acute period of ischemic stroke. Although obtained results demonstrate negative effect of increased MPIF-1/CCL23, Gro-a/CXCL1, IL-16 and Eotaxin-2/CCL24 concentrations on the improvement of motor and cognitive impairments, further studies are needed to verify the CXC and CC subfamilies chemokines as prognostic markers of patient’s functional outcome in the acute period of ischemic stroke.
The Process of English Internationalization in the Ukrainian Educational Paradigm
Authors: Leleka Tetiana , Ivanenko Nadiia , Demeshko Inna , Kapitan Tetiana , Demchenko Inha 
Published: February 2024

The research is devoted to the study of the problem of English loanword adaptation in the Ukrainian youth slang as a result of innovative processes in the educational system caused by the flow of language globalization. The globalization of the English language as a result of the information revolution and of all human activity is an unprecedented phenomenon in the world language system that is altering widely held beliefs about literacy and foreign languages. The main hypothesis of the study is an increase in the number of borrowed words in the speech of the Ukrainian youth. The paper attempts to analyze the trends in the use of the loanwords that have Ukrainian one-word equivalents over 5 years, from 2016 to 2021. To obtain data on the use of loanwords, respondents aged 15–17 (school pupils), 18–20 (university students), and 21–23 (university graduates) have been interviewed. According to the problems mentioned, the article aims to describe the use of English loanwords in the Ukrainian language caused by language globalization. The study intends to explore whether Ukrainian speakers prefer to use English loanwords instead of the Ukrainian equivalents that are connected with the role of English in the educational system and whether gender is a significant factor in the use and further assimilation of English loanwords.
The Association of Childhood Parental Connection With Adult Flourishing and Depressive Symptoms
Authors: Whitaker Robert C. , Dearth-Wesley Tracy , Herman Allison N. 
Published: February 2024

OBJECTIVES
To determine whether a common measure of childhood emotional neglect, scored instead as a continuous measure of increasing parental connection, is associated with adult flourishing and depressive symptoms, and to compare the magnitude of these 2 associations.

METHODS
We pooled cross-sectional survey data from the Midlife in the United States study, collected from 2 national cohorts (2004–2006 and 2011–2014) of English-speaking, US adults, aged 25 to 74 years. Using the 5-item emotional neglect subscale of the Childhood Trauma Questionnaire, a score of increasing childhood parental connection was created by not reverse-scoring responses. The adult outcomes were standardized scores of flourishing, from Ryff’s Psychological Well-Being Scale, and depressive symptoms, from the Center for Epidemiologic Studies Depression Scale.

RESULTS
Data were available for 2079 of 2118 participants (98.2%). The mean (SD) age was 53.1 (12.6) years and 54.6% were female. After adjusting for covariates (age, gender, race and ethnicity, marital status, chronic disease, socioeconomic disadvantage), the adult flourishing score was 0.74 (95% confidence interval 0.63–0.86) SD units higher in those in the highest quartile of childhood parental connection compared with the lowest, whereas the depressive symptoms score was lower by a similar magnitude (−0.65 [95% confidence interval −0.77 to −0.54] SD units).

CONCLUSIONS
When emotional neglect is reframed as parental connection, it has associations with adult flourishing and depressive symptoms that are of similar magnitude but opposite direction. Clinicians and researchers should consider the more positive and aspirational frame of parental connection and its potential contribution to life course flourishing.
High rates of intestinal colonization with carbapenemase producing Enterobacteriaceae in hematopoietic stem cell transplant recipients
Authors: Ayari Ikram , Chebbi Yosra , Raddaoui Anis , Belloumi Dorra , Frigui Siwar , Werhni Rim , Ben Othmen Tarek , Abedejlil Nour , Achour Wafa 
Published: February 2024

AbstractCarbapenem resistant Enterobacteriaceae (CRE) are major human pathogens because, these cause high number of difficult-to-treat infections. Allogeneic hematopoietic stem cell transplant (AHSCT) recipients are highly exposed to these type of bacteria. The aim of our study was to investigate prevalence of CRE colonization in AHSCT patients and to determine genes encoding carbapenem resistance. A retrospective study conducted between January 2015 and December 2019, involved 55 patients colonized with CRE strains. We determined the rate of antibiotic resistance according to European Committee on Antimicrobial Susceptibility Testing (EUCAST) and the carbapenem resistance genes by PCR assays for genes encoding most frequent β-lactamases namely, blaGES, blaKPC, blaIMI, blaNDM, blaVIM, blaIMP and blaOXA-48. Eighty-one episodes of CRE colonization were recorded in 55 patients, mainly suffering from acute leukaemia (30%) and aplastic anemia (26%). History of hospitalization was noted in 80 episodes. Prior antibiotic treatment, severe neutropenia and corticosteroid therapy were respectively found in 94%, 76% and 58% of cases. Among the 55 patients, six patients (11%) developed a CRE infection. The CRE responsible for colonization were carbapenemase producers in 90% of cases. They belonged mostly to Klebsiella pneumoniae (61/81) and Escherichia coli species (10/81). Antibiotic resistance rates were 100% for ertapenem, 53% for imipenem, 42% for amikacin, 88% for ciprofloxacin and 27% for fosfomycin. Molecular study showed that blaOXA-48 gene was the most frequent (60.5%), followed by blaNDM (58%). Thirty-five (43%) strains were co-producers of carbapenemases. In our study, we report a high rate of CRE intestinal colonization in AHSCT recipients of our center.
DEVELOPMENT OF APPLIED ONTOLOGY FOR THE ANALYSIS OF DIGITAL CRIMINAL CRIME
Authors: Vlasenko L. O. , Lutska N. M , Zaiets N. A. , Savchenko T. V. , Rudenskiy A. A. 
Published: February 2024

Context. A feature of the modern digital world is that crime is often committed thanks to the latest computer technologies, and the work of law enforcement agencies faces a number of complex challenges in the digital environment. The development of information technology and Internet communications creates new opportunities for criminals who use digital traces and evidence to commit crimes, which complicates the process of identifying and tracking them.
Objective. Development of an applied ontology for a system for analyzing a digital criminal offense, which will effectively analyze, process and interpret a large amount of digital data. It will help to cope with the complex task of processing digital data, and will also help automate the process of discovering new knowledge.
Methods. To build an ontological model as a means of reflecting knowledge about digital crime, information was collected on existing international and domestic classifications. The needs and requirements that must be satisfied by the developed ontology were also analyzed. The creation of an ontological model that reflects the basic concepts, relationships in the field of digital criminal offense was carried out in accordance with a recognized ontological analysis of a specialized subject area.
Results. An applied ontology contains the definition of entities, properties, classes, subclasses, etc., as well as the creation of semantic relationships between them. At the center of the semantics is the Digital Crime class, the problem area of which is complemented by the interrelated classes Intruder, Digital evidence, Types of Crime, and Criminal liability. Such characteristics as motive, type of crime, method of commission, classification signs of digital traces and types of crime, as well as other individual information were assigned to the attributes of the corresponding classes. An ontological model was implemented in OWL using the Protégé software tool. A feature of the implementation of the applied ontology was the creation of SWRL rules for automatically filling in additional links between a class instance. Manual and automatic verification of the ontology showed the integrity, consistency, a high degree of correctness and adequacy of the model. The bugs found were usually related to technical aspects and semantic inconsistencies, which were corrected during further development iterations.
Conclusions. The research confirmed the effectiveness of the developed applied ontology for the analysis of digital criminality, providing more accurate and faster results compared to traditional approaches.
THE FREQUENCY METHOD FOR OPTIMAL IDENTIFICATION OF CLOSE-LOOP SYSTEM ELEMENTS
Authors: Osadchyi S. І. , Zozulya V. A. , Kalich V. M. , Timoshenko A. S. 
Published: February 2024

Context. The article is devoted to overcoming the contradictions between the assumptions adopted in known methods of closedloop control system identification and the design and conditions of its operation. The article presents a new method of identifying the transfer functions matrix of a two-level closed-loop control system element, which functions under the conditions of multidimensional stationary centered random influences.
Objective. The purpose of the study, the results of which are presented in this paper, is to extend the indirect identification method to the case of estimating one of the two-level closed-loop control system elements’ dynamics model based on passive experiment data.
Method. To solve the optimal identification problem, a variational method for minimizing the quality functional on the class of fractional-rational transfer function matrices was used.
Results. As a result of the research, the identification problem formulation was formalized, the rules for obtaining experimental information about the input and output signals were determined, the rules for identifying the transfer functions matrix of a two-level closed-loop control system element, which minimizes the sum of the variances of identification errors in the frequency domain, and the verification of these rules was carried out.
Conclusions. Justified rules allow to correctly determine transfer functions matrices of the closed-loop systems selected element when fulfilling the defined list of conditions. The closed-loop systems control paths signals analysis proves the possibility of the effect of changing these signals statistical means, even under conditions of only centered stationary input influences actions on the system. Based on this, the further development of research can be aimed at overcoming such effects.
Ampliação da rede de cuidado ao paciente portador de feridas de difícil cicatrização: um relato de experiência
Authors: Gonçalves Maria Isabel Dantas Gomes , Sousa Milena Nunes Alves de 
Published: February 2024

Objetivo: Objetiva-se demonstrar que o cuidado continuado na atenção básica à saúde tem um pilar importante para melhoria da qualidade de vida dos usuários, assim como, intensifica a relação médico, paciente e unidade de serviço. Além de, reforçar que o curativo diário em feridas de difícil cicatrização traz grandes benefícios para a população e redução de tempo de tratamento, cura e prevenção de outras enfermidades. Metodologia: É um relato de experiência realizado com 5 pacientes portadores de feridas de difícil cicatrização no qual ocorreu tratamento continuado das lesões, além de educação em saúde. Assim, foi considerada a implementação da metodologia da problematização com foco no estigma, através do Arco de Maguerez, para estudo da população de uma UBS na cidade de Malta - PB. Resultados: Após continuidade do tratamento e dos curativos diários das lesões, foram observados melhora da cicatrização completa das feridas, assim como melhor adesão da população aos cuidados continuados que o serviço oferece, além da interação entre equipe e paciente. Considerações Finais: Essa abordagem permitiu melhoria nos tratamentos e resoluções das lesões de difícil cicatrização, além de melhor interação entre Unidade de Serviço, equipe de saúde e população.
Atenção à saúde mental da pessoa idosa na atenção primária: relato de experiência utilizando o Arco de Maguerez
Authors: Vilar Ingrid de Assis , Sousa Milena Nunes Alves de 
Published: February 2024

Objetivo: Relatar as vivências de atividades multiprofissionais realizadas com grupos de idosos em unidade básica de saúde. Metodologia: Relato de experiência, baseando-se na aplicação do Arco de Maguerez, realizado na Unidade Básica de Saúde VI Roberval Eliseu da Nóbrega, localizada no bairro São Sebastião, no município de Santa Luzia, na Paraíba, no período de agosto a novembro de 2023. Relato de experiência: Durante 3 encontros foi abordado sobre a necessidade de desmame de benzodiazepínicos, as mudanças patológicas e naturais do processo de envelhecimento, os medos e estigmas relacionados a essa vivência e as adaptações necessárias para promover maior qualidade de vida. Foram realizados bingos e momentos de prática de exercício físico. As ações demonstraram impactos positivos na saúde mental dessa população, esse fato foi constatado pela diminuição de queixas envolvendo depressão, ansiedade e distúrbios do sono dentro das consultas médicas, além dos feedbacks positivos dos cuidadores. Conclusão: A realização dos encontros impactou de modo positivo a saúde mental dos idosos, como a menor recorrência de queixas álgicas e nos quadros de tristeza após os encontros, os feedbacks dos cuidadores falando que os idosos estão mais ativos em casa, além da percepção do aumento do vínculo com a equipe de saúde.
NOVEMBER 13 – IVAN LYPA MEMORIAL DAY (24.02.1965, KERCH - 13.11.1923, VYNNYKY)
Authors: Kucherenko Svitlana 
Published: February 2024

Events dedicated to the 100th anniversary of the death of Ukrainian politician and cultural figure Ivan L. Lypa were held on 13 November 2023 in Vynnyky.
Utilization of Inulin from Mangrove Apple and Pineapple Juice as Prebiotic Drink to Recovery Covid-19 Patients
Authors: Pramono Yoyok Budi , Mulyani Sri , M. Legowo Anang , Al-Baarri Ahmad Ni’matullah , Maula Bernadine Nathania , Olivia Afri Kusuma Daniella , Gangsar Listya Angelique 
Published: February 2024

Amidst the COVID-19 pandemic, some individuals have turned to functional foods in an effort to bolster their immune systems. One such functional option is prebiotic drinks. These beverages are crafted from fermented sugars, which serve as a carbon source for lactic acid bacteria. To enhance their functional properties, prebiotic drinks often incorporate inulin—a type of prebiotic. Traditionally, these drinks are milk-based, but for those who cannot tolerate dairy, alternatives have emerged. For instance, pineapple-based prebiotic drinks enriched with inulin from mangrove apples have gained popularity. The process involves extracting inulin from mangrove apples and combining it with pineapple to create a probiotic drink. The resulting beverage derives its sweetness from the natural sugars found in pineapples and mangrove apples. Pineapple contains approximately 2.32% glucose, 1.42% fructose, and 7.89% sucrose, while mangrove apples boast 5.08% inulin, 9.67% soluble dietary fiber, and 0.66% FOS. These sugars serve as nourishment for lactic acid bacteria, ultimately stimulating the production of IgG and IgM antibodies. In summary, the combination of inulin-rich mangrove apples and pineapple’s total soluble solids can contribute to fortifying the body’s immune system during the COVID-19 pandemic.
STRATEGI PENGELOLAAN BERITA WEBSITE UIN RADEN FATAH PALEMBANG SEBAGAI MEDIA INFORMASI UNIVERSITAS
Authors: Rustiana Erna , Hamidah Hamidah , Duku Sumaina 
Published: February 2024

"The strategy of managing the UIN Raden Fatah website news as a university information media. The problem in this thesis is that people want things that are fast paced. Therefore, in adjusting people's behavior, news presentation is increasingly shifting from starting to display content in the form of long form writing, switching to short forms and finally readers are interested in the news delivered so that it attracts readers to visit the UIN Raden Fatah website and provide feedback (clickbait ). The purpose of this research is to find out how the strategy of managing the news website of UIN Raden Fatah Palembang. This research uses a qualitative descriptive approach through a survey of the object under study, in qualitative research which means the researcher himself or with the help of others, data collection tools in the form of interviews, observations, and documentation. Types and sources of qualitative research data were obtained directly from original sources (not through intermediaries). Primary data sources were obtained through depth interviews such as interviewing the head of Public Relations Dra. Elisma Harfiani, MM and several communicants. Secondary data is used as a complement in the study. Determining the news strategy first determines editorial management for the news strategy consisting of two strategic forms including (1) Writing that is emphasized by the editor of www.radenfatah.ac.id, namely procuring long titles that are rich in keywords and dividing news content into several pages, ) The news policy strategy is an effort to maintain media branding to reap as many visitors as possible by developing content in it. The obstacle that occurs in the management of UIN Raden Fatah's website news is the lack of human resources.
Keywords: strategy, management, media, news and website
PENGARUH PEMBAWA ACARA INDONESIA LAWYERS CLUB SUKARNI ILYAS DI TV ONE TERHADAP MINAT MENONTON MAHASISWA UIN RADEN FATAH PALEMBANG (STUDI PADA MAHASISWA JURNALISTIK 2017)
Authors: Laras Sakti Iqbal Pratama , Sihabuddin M Amin , Dewi Emi Puspita 
Published: February 2024

This study aims to determine the extent of the influence of “Sukarni Ilyas” Talkshow Indonesia Lawyer club against interest watch (Studies on students UIN Raden Fatah Palembang Jurnalism force in 2017). The population of this study of UIN Raden Fatah, the Faculty of Da’wah and communication Departement Jounalism as many as 91 students. The determination of the analyzed uses analysis based on the characteristics of respondents, namely based on gender and based on class. Based on gender in which sample obtained by (38,5 %) 35 male students and (61,5 %) 56 female students. Based on the class of A, B, C, and D played as if more students were in a D class I namely as many as 27 students were 29.7 % of respondents. This study in a quantitative study and assisted with the programs SPPS V 16 and data collection uses kusioner. kusioner that is covered, namely alternatives answers have been determined before researchers. Based on analysis of simple regressing obtained watching 0,814 (81%) which shows positive influence againts the host so if the presenter increased, the interest increased. Based on signifikasi parsial (test t) obtained a value of host shows (X) 0,5 < 0F 7.327> t-it 1.986 (7.327>1.986 and sig 0.50). Based on the coefficient of kolerasi obtained a value of R 0.613 meaning that the relationship (realtion) between the host of watching has a strong relationship of 61.3%. So that the results of this study showed that a particulary strong influence between hosts interest in watch UIN Raden Fatah, Faculty of Da’wah and communication depatement of Journalists 2017.
Keywords: Quantitative researcher, infulene talkshow, Interest watching