bluuebunny/crossref_metadata_2025_split huggingface dataset:
Femoral Vein Access for Central Venous Catheterization as a Rescue for Failed Peripheral Access for Blood Sampling, Intravenous Nutrition, and Drug Delivery
Authors: Aslam Mohd , Tabish Iram , Alam Mahfooz , Husain Amir , Ashraf Sheikh , Fatima Razeen , Irfan Mohd 
Published: February 2025

Abstract

Introduction:
A central line is crucial to the management of critically ill patients. The decision regarding the insertion of a central line would be to deliver multiple medications for continuous infusion of chemotherapy, for parenteral nutrition, and to deliver vesicant drugs.

Materials and Methods:
Our study comprised 45 patients, 26 males and 19 female patients, who were catheterized via femoral vein after a failed peripheral access, either due to refusal of consent for subclavian or internal jugular catheterization, unsuccessful access to the internal jugular vein and subclavian veins, or extreme patient sickness. Nineteen patients were administered prolonged antibiotics and antifungals for pyelonephritis, 11 patients were cannulated for the management of severe shock in which peripheral access was difficult, and 15 critically ill patients were administered long-term medication and parenteral nutrition via the femoral route.

Results:
In our study, we found that seven patients developed blood ooze from the puncture site, four had difficulty accessing it because of pre-existing partial thrombus in the vein, and three developed hematoma at the puncture site. Later, six patients developed an infection at the catheter site, which was managed by intravenous antibiotics; six patients developed delayed onset bleeding from the puncture site; four patients developed a device dysfunction due to poor blood flow, and two patients developed deep vein thrombus. The rest of the patients did not develop any catheter-related complications.

Conclusion:
Central venous access plays a crucial role in the management of critically ill patients as well as in those requiring long-term drug therapy. The internal jugular, subclavian, and femoral veins are three common sites for this access.
Strengths and Weaknesses of Top Indian Medical Colleges across Key Domains: Analysis of National Institutional Ranking Framework 2024 Rankings
Authors: Mondal Himel , Dash Akhyaya Kumar , Mondal Shaikat , Behera Joshil Kumar 
Published: February 2025

Abstract

Background and Aim:
The National Institutional Ranking Framework (NIRF) is a key tool for assessing the performance of Indian higher education institutions. Identifying the strengths and weaknesses of top-ranked medical colleges is crucial for strategic planning and resource allocation. This study analyzed the NIRF 2024 rankings to pinpoint areas of excellence and deficiency in these institutions.

Methods:
This cross-sectional study utilized data from the NIRF 2024 rankings of medical colleges. Data from the top 50 medical colleges are available in the public domain. Their overall score of teaching, learning, and resource (TLR), research and professional practice (RP), graduation outcome (GO), outreach and inclusivity, and perception (PR) were calculated. Correlation coefficients were calculated to explore the relationship between overall rankings and individual domain scores.

Results:
From 182 registered institutions, the NIRF ranking provides the top 50 institutions. The highest score was for TLR (80.21 ± 6.04) and a similar score for GO (79.37 ± 8.02). The lowest score was for PR (33.41 ± 19.73) and RP also had an identical score (36.46 ± 17.9), F (4, 245) =150.2, P < 0.0001, r
2 = 0.71. There was a positive correlation between the rank and all domain scores. The highest level of correlation was the RP score (r = 0.809, P < 0.0001) followed by PR (r = 0.644, P < 0.0001).

Conclusion:
The NIRF analysis shows that top medical institutions excel in teaching and outcomes but lag in research, a critical determinant of their overall score. Institutions should prioritize enhancing research output, securing grants, and collaborating with top research bodies, while also improving visibility through media, alumni engagement, and academic partnerships.
Evaluating the Feasibility of Mobile Screening Units for Early Detection of Cancer in the Community
Authors: Chakrabarti Jayanta , Mandal Ranajit , Vernekar Manisha , Banerjee Dipanwita , Sengupta Arunabha , Bose Sreeya 
Published: February 2025

Abstract

Background:
Mobile screening units (MSUs) offer an effective approach to increasing access to cancer screening and reducing geographical and financial barriers. This study reports the outcomes of MSUs in cervical, breast, and oral cancer screening.

Methodology:
The MSU was integrated into a bus with three compartments, with designated areas for registration, cervical cancer screening, oral visual examination (OVE), and mammography. Between May 2023 and August 2024, 178 community camps were held in Kolkata and nearby districts. A total of 6205 women underwent cervical, breast, and oral cancer screening. Women aged 30–60 years were screened for cervical cancer by high-risk human papillomavirus (hrHPV) DNA test while breast cancer screening was conducted using clinical breast examination. Any abnormal findings on examination were referred for mammography.

Results:
HrHPV positivity was detected in 323 (5.3%) women by Cobas assay. Following this, 218 women were referred for colposcopy and treatment. Following clinical breast examination, 316 women were referred for mammography. In addition, 28 women with suspicious breast lesions were referred to the Chittaranjan National Cancer Institute for further management. Abnormal OVE was diagnosed in 18 women who were advised to quit tobacco.

Conclusion:
MSUs serve as a valuable tool for expanding access to cancer screening in resource-limited settings and reduce the global burden of preventable cancers as well as meet cancer screening targets.
Implementation and Adaptation of Pathway of Resuscitative Endovascular Balloon Occlusion of the Aorta after Traumatic Injury
Authors: Al-Hassani Ammar , Wahlen Bianca M. , El-Menyar Ayman , Al-Hassani Ibrahim , Khan Naushad A. , Galwankar Sagar , Rizoli Sandro , Al-Thani Hassan 
Published: February 2025

Abstract
Resuscitative endovascular balloon occlusion of the aorta (REBOA) is an invented method to facilitate a minimally invasive occlusion of the aorta to stop a life-threatening hemorrhage. This review described an established pathway for noncompressible exsanguination (REBOA procedures) in trauma patients at a Level 1 trauma center. A detailed description starting from the structural changes of the hospital and facilities itself, the initial thoughts, implementation of the process, and continuous revision and improvement of guidelines were discussed. A multidisciplinary core team consisting of trauma surgeons, anesthesiologists, interventional radiologists, and operating room (OR) staff developed step-by-step clinical practice guidelines for using REBOA at our trauma center. A comprehensive training program for specialized procedural training was implemented to ensure the competency of all relevant medical personnel in managing trauma patients. The REBOA guidelines underwent plan-do-check-act quality cycle improvement until the latest guidelines were reached with each use of REBOA in a trauma patient, leading to further auditing of the guidelines to identify areas for improvement. The current review discusses the critical role of adopting innovative technologies and adapting protocols in trauma care, particularly for vulnerable patients with a high risk of morbidity and mortality. Continuous process improvement, procedural refinement, and evolving guidelines are essential prerequisites for optimizing patient outcomes. We described a valuable framework for other trauma programs to implement and adapt similar endovascular bleeding control approaches, thereby potentially enhancing patient care.
Detection of Chikungunya Virus in Aedes aegypti in Ciudad Juárez, Chihuahua, Mexico
Authors: Hernández-Acosta Eduardo , Covarrubias Antonio De la Mora , Fernández-Salas Idelfonso , Escárcega-Ávila Angélica , Olivera Isabel Passalacqua , Jiménez-Vega Florinda 
Published: February 2025

Background & objectives:
Chikungunya fever is caused by an arbovirus transmitted primarily by the Aedes Aegypti mosquito, which is prevalent in Mexico along with other pathogens carried by this vector. This study aimed to detect the presence of the Chikungunya virus in A.
Aegypti mosquitoes in a vulnerable area of Ciudad Juárez, Chihuahua.

Methods:
Mosquitoes were collected from both indoor and outdoor areas of 87 households using BG-GAT and Gravid traps during the fall of 2015. The presence of CHIKV was determined molecularly using reverse transcriptase polymerase chain reaction (RT-PCR), and the infection rate was calculated using the PooledInfRate program.

Results:
A total of 328 female Ae. aegypti mosquitoes were captured, grouped into 131 pools. 66% of them tested positive for CHIKV. The infection rate, as measured by Minimum Infection Rate (MIR), was 26%, and Maximum Likelihood Estimation (MLE) was 15.2%.

Interpretation & conclusion:
The presence of the infected vector was confirmed in the study area. This first report in the region highlights the need for active epidemiological surveillance to prevent potential Chikungunya outbreaks in this border population.
Outcome of dengue infection and risk factors for severe dengue in Indian children
Authors: Panchanadikar Neeraj T , Palkar Sonali H , Lalwani Sanjay K 
Published: February 2025

Background & objectives:
Dengue, a fast-growing vector-borne disease, has an estimated case- fatality rate of 5%. India is largely affected by dengue. Due to its unpredictable course and non-availability of specific treatment, timely identification of risk factors for severe dengue and its management is crucial. This study aimed to evaluate the clinical profile of children admitted to a tertiary care hospital with dengue, including their outcome, and identify the risk factors for severe dengue.

Methods:
This prospective observational study included children admitted with serologically confirmed dengue. World Health Organization classification was used to classify the illness. The details of demographic characteristics, history, clinical examination, laboratory parameters, and outcome were noted. Various risk factors, associated with severe dengue including clinical and laboratory parameters, were determined using crude and adjusted odds ratios at 95% CI.

Results:
Out of 157 enrolled children, 51 (32.5%) had severe dengue, and 5 (3.2%) died. Severe dengue showed no predilection for age, gender, and baseline IgG positivity. Multivariate- logistic regression analysis identified only fever ≥39°C [aOR 4.06 (1.60-10.27)] and petechiae [aOR 9.91(3.07-32.03)] as the clinical risk factors for severe dengue. Prolonged prothrombin time (>14s) [aOR 37.21(1.46-946.23)] and platelet count less than 50,000/cu mm [aOR 12.83(1.12-147.17] were observed as independent laboratory risk factors for severe dengue.

Interpretation & conclusion:
Simple clinical measures like a detailed history of fever >39°C and examination, especially for petechiae, should caution clinicians against progressing to severe dengue. Along with platelet count, prothrombin time should also be monitored during the laboratory investigations.
Early Physiotherapy Intervention In Case of Infective Spondylitis with Para Spinal and Epidural Abscess: A Case Report
Authors: Kshipra Shastri , Shyam (PhD) Prof. Dr. Ganvir 
Published: February 2025

Background- Infectious spondylitis is an unusual but serious cause of low back pain. Epidural and paraspinal abscesses are atypical diseases with a high risk of morbidity and mortality that are frequently discovered later in the course of the disease. . Method – A 52 year male had complaint of fever, pain in back and was unable to move his bilateral lower limb has given early rehabilitation six days a week for eight weeks. PRT and MWM was given for 3 times per week for 2 weeks Result – showed significant improvement in ROM, strength, ASIA and FIM score. Conclusion - Early diagnosis and physiotherapy intervention is the key to an optimal outcome in case of infective spondylitis with epidural and paraspinal abscess.
BOOK REVIEW - Practical Guide -Physical Therapy in Chronic Respiratory Diseases by Rik Gosselink, PT,PhD ,FERS
Authors: Ketkar Berry Aditi , Abhijit, (PhD) Prof. Dr. Diwate 
Published: February 2025

Title of the book: “Practical Guide Physical therapy in chronic respiratory diseases.
Editor: Professor Rik Gosselink
Department of Rehabilitation Sciences KU Leuven; Department of Respiratory Rehabilitation, University Hospitals Leuven, Belgium.
Date of publication: 4th December 2023
Place of Publication: Middletown, DE, USA
ISBN number: 9798393437183
Total number of pages: 110
Effectiveness of Mindfulness Meditation on Improving Mental Well Being of Undergraduate Physiotherapy Students - A Quasi Experimental Study
Authors: Srushti Gandhare , Ashwini Kalsait 
Published: February 2025

Aim- To study the effectiveness of mindfulness meditation on the mental well-being of undergraduate physiotherapy students. Objective- To see the improvement in the mental well-being after the mindfulness meditation by using Warwick Edinburg mental well-being scale in undergraduate physiotherapy students. Methodology - A pre-test post-test Quasi experimental study was done in underground physiotherapy students in Jalgaon. A total of 56 participants were taken in a group by purposive sampling method according to inclusion and exclusion criteria. Warwick- Edinburg scale was used to check the mindfulness of the participant. Result- the mean difference of the pre and post intervention was 6.786. The t and p values were 39.823 and < 0.0001 respectively. Conclusion- There was significant improvement in the mental well-being of the undergraduate physiotherapy students following one month mindfulness meditation.
Загадка Табынской иконы Божией Матери
Authors: Пчелинцева К. О. 
Published: February 2025

В статье дается краткий обзор истории Табынской иконы Божией Матери, ее перемещения на территорию Китая, а также делается попытка, собрав максимальное количество версий о ее возможном местонахождении, разобраться в их достоверности и сделать вывод о наибольшей вероятности ее нынешнего нахождения. С большой вероятностью можно говорить о том, что было два образа: подлинник и список. Поэтому, и искать нужно две иконы и в разных местах. Статья представляет собой расширенный текст доклада, прочитанного на VII научной конференции «Православие на Дальнем Востоке», проходившей 17–18 ноября 2022 г. в Санкт-Петербурге в Санкт-Петербургском государственном университете и Санкт-Петербургской Духовной Академии.
The article provides a brief overview of the history of the Tabyn Icon of the Mother of God, its transfer to the territory of China, and also makes an attempt, having collected the maximum number of versions about its possible location, to understand their reliability and draw a conclusion about the highest probability of its current location. It can be said with a high probability that there were two images: the original and the copy. Therefore, it is necessary to look for two icons and in different places. The article is an extended text of the report read at the VII scientific conference “Orthodoxy in the Far East”, which was held on November 17–18, 2022 in St. Petersburg at the St. Petersburg State University and the St. Petersburg Theological Academy.
Антон Владимирович Карташёв: детство и годы обучения в Пермской духовной семинарии (1875–1895)
Authors: Тищенко С.А. 
Published: February 2025

Статья посвящена годам становления А. В. Карташёва, которые включают в себя изучение данных о происхождении рода и положении родителей будущего обер-прокурора Св. Синода. Особое место уделяется восприятию образования как безусловной ценности в семье Карташёвых. Данные о времени обучения А. В. Карташёва в духовном училище и семинарии реконструируются на материале делопроизводственных документов соответствующих учебных заведений, а также с помощью данных, выявленных в источниках личного происхождения. Восстанавливается исторический фон обучения церковного историка в указанных учебных заведениях: прослеживается состояние духовного образования, особенности быта конкретного учебного заведения, интеллектуальная и воспитательная среда. Автор делает вывод, что годы обучения и семейная атмосфера оказали колоссальное влияние на мировоззрение и психологию А. В. Карташёва, заложили фундамент его научных интересов, стремления к церковному служению.
The article is devoted to the formative years of A. V. Kartashev, which include the study of data on the origin of the family and the status of the parents of the future Chief Prosecutor of the Holy Synod. Special attention is paid to the perception of education as an absolute value in the Kartashev family. Data on the time of A. V. Kartashev’s study at the theological school and seminary are reconstructed based on the materials of the office documents of the relevant educational institutions, as well as with the help of data identified in personal sources. The historical background of the training of the church historian in the aforementioned educational institutions is reconstructed: the state of spiritual education, the peculiarities of the life of a particular educational institution, the intellectual and educational environment are traced. The author concludes that the years of study and the family atmosphere had a colossal impact on the worldview and psychology of A. V. Kartashev, laid the foundation for his scientific interests, aspirations for church service.
ИЗУЧЕНИЕ ИСТОРИИ ЦЕНТРАЛЬНОЙ АЗИИ РУССКИМИ УЧЕНЫМИ В СЕРЕДИНЕ ХIХ ВЕКА
Authors: Хуррамова Саодат 
Published: February 2025

Из истории известно, что территория Средней Азии издавна находилась в центре внимания путешественников, историков, географов. Ряд ученых написали исторические труды о Центральной Азии. В данной статье анализируются данные русских учёных, посетивших Среднюю Азию в XIX веке. Это позволяет провести сравнительно-исторический анализ данных.
Review on Vishajanya Janapadodwamsa Vyadhi w.s.r. to Environmental Toxicity
Authors: pujar Bhavani , Budihal Shivakumar 
Published: February 2025

Environmental toxicology is a multidisciplinary domain of science, which occupies an important niche, overlapping the field of toxicology. It focuses on humans and other living beings and therefore plays an important role in addressing public health challenges. With increasing numbers of environmental problems, there is a need for immediate health solutions. Environmental toxicity and its health hazards are not a new global issue; it has been in practice for 5,000 years. In olden days, kings, when they entered enemy kingdoms along with the military, faced the threat of being poisoned by entities like air, water, land, grass, and cattle feed. In present days, because of human activities, industries, pesticides, chemicals, and other unhealthy behaviors, the environment is getting poisoned and affecting the health of not only human beings but also the other living creatures of the earth and aquatic ecosystems. The present COVID-19 crisis is also a kind of environmental toxicity affecting the whole world. This paper is an attempt to review the health problems and methods of purification of such environmental particulates explained in classical texts and discuss the adaptation of these methods for challenging problems related to environmental toxicity in the present era.
PENERAPAN METODE K-MEANS CLUSTERING UNTUK PEMETAAN PERBAIKAN JALAN DI KOTA BOGOR
Authors: Wulandari Annisa , Irmayansyah  , Ningrum Leny Tritanto 
Published: February 2025

Perbaikan jalan sangat penting untuk menjaga fungsinya dalam menunjang ekonomi dan aktivitas sosial. Perbaikan jalan yang terencana bukan hanya sebuah kebutuhan teknis, tetapi juga merupakan investasi untuk keselamatan, efisiensi, dan kesejahteraan masyarakat, Oleh karena itu penting bagi pemerintah dan instansi terkait untuk melakukan perencanaan yang matang dalam program perbaikan infrastruktur jalan. Adapun metode yang digunakan dalam mengelompokan data perbaikan jalan yaitu algoritma K-Means dengan hasil keluaran berupa tiga kluster dimana Klaster 1 merupakan klaster dengan tingkat perbaikan Tinggi, klaster 2 merupakan klaster dengan tingkat perbaikan Sedang, dan klaster 3 merupakan klaster dengan tingkat perbaikan Rendah dan sudah dilakukan uji validitas cluster menggunakan Silhouette Coefficient terhadap algoritma K-means yang diterapkan dengan nilai yang diperoleh sebesar 0,659 yang berarti cluster yang dibentuk termasuk kedalam kategori struktur baik . Pada ptoyotype aplikasi yang dibangun telah dilakukan uji kelayakan oleh ahli sistem menggunakan metode white box dengan hasil persentase kelayakan sebesar 100% yang dapat dikategorikan ke dalam interpretasi sangat layak”, juga telah dilakukan juga uji kelayakan oleh pengguna menggunakan instrumen Post-Study System Usability Questionaire (PSSUQ) dengan hasil perolehan yakni nilai kepuasan secara keseluruhan sebesar 78,9%, yang artinya aplikasi ini layak digunakan.
VALIDITAS DAN PRAKTIKALITAS LKPD HIDROLISIS GARAM BERBASIS GUIDED DISCOVERY LEARNING TERINTEGRASI ETNOSAINS UNTUK FASE F SMA
Authors: JELITA FARAH , ANDROMEDA ANDROMEDA 
Published: February 2025

The independent curriculum demands discovery-based learning, so the use of teaching materials must be adjusted based on the curriculum and the needs of students. In chemistry learning, the integration of ethnoscience can improve conceptual understanding and problem-solving skills by connecting knowledge theory with real-life phenomena, such as culture in society. This study aims to determine the level of validity and practicality of the salt hydrolysis LKPD based on guided discovery learning integrated with ethnoscience that was developed. The research was conducted using the 4D research model (define, design, develop, and disseminate), the limitations in this study were carried out until the development stage of the validity test and practicality test. The validity test was carried out on experts and then tested on 32 students in phase F of SMA N 1 Batang Anai. The results of the study obtained an Aiken's V value of 0.85 (valid) and the level of practicality of teacher and student responses was 93% and 86% (very practical), respectively. These results indicate that the salt hydrolysis LKPD based on guided discovery learning integrated with ethnoscience for phase F of SMA is valid and very practical to use in learning after being tested for its effectiveness.
ABSTRAKKurikulum merdeka menuntut pembelajaran berbasis penemuan, maka penggunaan bahan ajar harus disesuaikan berdasarkan kurikulum serta kebutuhan peserta didik. Dalam pembelajaran kimia, pengintegrasian etnosains dapat meningkatkan pemahan konsep serta keterampilan pemecahan masalah dengan menghubungkan teori pengetahuan dengan fenomena kehidupan nyata, seperti kebudayaan dalam masyarakat. Penelitian ini bertujuan untuk mengetahui tingkat validitas dan praktikalitas LKPD hidrolisis garam berbasis guided discovery learning terintegrasi etnosains yang dikembangkan. Penelitian diakukan menggunakan model penelitian 4D (define, design, develop, dan disseminate), pembatasan pada penelitian ini dilakukan hingga tahap develop uji validitas dan uji praktikalitas. Uji validitas dilakukan kepada para ahli kemudian diuji cobakan kepada 32 peserta didik fase F SMA N 1 Batang Anai. Hasil penelitian diperoleh nilai Aiken’s V sebesar 0,85 (valid) serta tingkat praktikalitas respon guru dan peserta didik masing-masing sebesar 93% dan 86% (sangat praktis). Hasil ini mengindikasikan bahwa LKPD hidrolisis garam berbasis guided discovery learning terintegrasi etnosains untuk fase F SMA valid dan sangat praktis untuk digunakan dalam pembelajaran setelah diuji efektivitasnya.