bluuebunny/crossref_metadata_2025_split huggingface dataset:
The management of Darier's disease
Authors: Burge Susan M. 
Published: July 2006

AbstractDarier's disease (keratosis follicularis) is a rare, dominantly inherited condition which is characterised by the presence of warty papules and plaques on the trunk, scalp and flexures. Diagnostic nail changes are present in most patients. Suprabasal clefting, acantholysis and dyskeratosis are present in involved skin and the diagnosis may be confirmed by a skin biopsy. The disease never remits. Exacerbating factors such as heat, sweating and ultraviolet light should be avoided. Topical therapy with emollients, moderately potent corticosteroids and antimicrobials may provide some symptomatic relief, but have no effect on the progress of the disease. Oral retinoids are effective in most patients. Complications such as cutaneous infections, blistering and salivary gland obstruction may occur in some patients.
Mucosal presentation of Behçet's disease
Authors: Moyle Graeme , Chard Sue , Boag Fiona 
Published: July 2006

AbstractBehçet's disease is a multisystem disease with both mucosal and systemic presentations, infrequently seen in the UK and Northern Europe. We present the case of a 23‐year‐old Caucasian girl who presented with mucosal ulceration and in whom diagnosis was assisted by HLA testing.
The natural history of demodectic mites on the skin of the eyelid margin
Authors: English Frank P. , Zhang Guang Wen , McManus Don P. , Home Felicity 
Published: July 2006

AbstractBackground Demodectic mites can be readily studied on the eyelid margin.Methods This was undertaken by scanning electron microscopy of the skin of the lid margin of full thickness eyelid specimens obtained by surgery.Results The whole life cycle of Demodex folliculorum, including the egg, nymph and adult stages was observed by electron microscopy of this region. The tails of adult mites protrude from hair follicles and also lie close to eyelashes either singly or in groups.Conclusions The eyelid littoral appears to be a significant site for egg laying by demodectic mites, and both intact and broken eggs have been seen. At the other end of the life cycle when adult mites die the protruding opisthosoma develops cracks in the carapace and the tail breaks off. Spillage of abdominal contents occurs which can carry fungi and bacteria on to the skin surface. All stages of the parasite including numerous casts of the ecdysed carapace contribute to debris found on the skin surface of the eyelid.
High‐frequency sonography of the skin
Authors: Fornage Bruno D. , Duvic Madeleine 
Published: July 2006

AbstractThis article reviews and illustrates the current applications of high‐frequency (20‐MHz) ultrasound imaging of the skin. This new imaging technique for the skin has gained popularity with the advent of commercially available dedicated ultrasound equipment. The normal ultrasound appearance is described first. Ultrasound features of benign and malignant skin tumors and inflammatory conditions are then described. The accurate delineation of the deep margins of a lesion and the non invasive measurement of its thickness represent an aid in evaluating skin tumors and monitoring the response to therapy of inflammatory conditions.
Pemphigus vegetans of Hallopeau following pemphigus foliaceus
Authors: Cecchi R. , Tuci F. , Brunetti L. , Bartoli L. , Pavesi M. , Giomi A. 
Published: July 2006

AbstractA 69‐year‐old woman previously affected with pemphigus foliaceus developed pustular lesions followed by verrucous vegetations, localized in the left sub‐mammary fold. Histological examination of vegetating lesions showed consistent acanthosis and papillomatosis with intraepidermal microabscesses containing eosinophils. Direct immunofluorescent examination evidenced intraepithelial IgG and C3 deposits. Circulating pemphigus antibodies were positive at titre 1: 160. This case suggests a clinical link between pemphigus vegetans and pemphigus foliaceus.
Occupational allergic contact dermatitis and composition of acrylates in dentin bonding systems
Authors: Kanerva Lasse , Henriks‐Eckerman Maj‐Len , Estlander Tuula , Jolanki Riitta , Tarvainen Kyllikki 
Published: July 2006

AbstractBackground Dentin‐bonding systems contain sensitizing acrylates. They are increasingly used in dentistry, but only few cases of allergy have been encountered.Objective This study reports observations on eleven patients sensitized by acrylates in dentin‐bonding compounds. Furthermore, the composition of dentin‐bonding products was analysed and compared with the information given in the material safety data sheets.Methods Patch testing was performed to reveal allergic contact dermatitis, and chamber provocation tests to reveal possible respiratory sensitivity. Gas chromatography/mass spectrometry was used to analyse the chemical composition of the bonding products.Results The most common sensitizer in our material of eleven patients was 2‐hydroxyethyl methacrylate (2‐HEMA). Another putative sensitizer, BIS‐GMA, used in dentin adhesives, did not cause sensitization. The typical allergic dermatitis localized to the fingertips (pulpitis). Seven of the eleven patients also developed paresthesia of the fingertips. One patient with positive patch test reactions to (meth)acrylates had pharyngitis hut no skin symptoms. One patient was sensitized because she had been patch tested with too high a concentration (undiluted) of dentin‐bonding components. Material safety sheets gave inaccurate or wrong information about the contents.Conclusion Dentin‐bonding acrylates are strong sensitizers, and even a single exposure may sensitize.
Single endolabial cysticercosis
Authors: Rodríguez‐Díaz E. , Armesto‐Alonso S. , Benito J.A. Velasco , Armijo M. 
Published: July 2006

AbstractCysticercosis is infestation of human tissues by Cysticercus cellulosae, the encysted larva of Taenia solium. An endemic disease in tropical countries, especially in Latin America, an increase is expected in its frequency in Europe because of increasing shifts in population. We report the case of a Spanish woman who had lived for some time in Bolivia and Peru who presented at our Department with a tumoral growth on the mucosa of her lower lip. Clinically, this was interpreted as a mucocele (salivary mucoid ‘cyst’); but histological study of the excised piece revealed, surprisingly, that it was a single–element cysticercosis.
Clinical features and outcome of first presentation anogenital warts in men and women
Authors: Birley Humphrey D.L. , Kupek Emil , Byrne Micheline , Whitaker Luke , Renton Adrian M. 
Published: July 2006

AbstractObjective Correlation of clinical features of patients on initial presentation of anogenital warts to outcome of treatment.Setting Outpatient genitourinary medicine clinic.Method Retrospective cohort analysis.Subjects Eighty‐three male and 60 female patients attending the clinic with first episode anogenital warts within a 3‐month period.Main outcome measures Relapse of warts following treatment. Total time for which treatment was given.Results Following one course of treatment, warts relapsed in 15% of the men, hut in only 37% of the women. After two courses, further relapse occurred in 31% of males and 18% of females (P < 0.001). Treatment for more than 6 months was required for 39% of men, but only 22% of women. Poorer outcome of treatment was related to larger size of warts at presentation. No significant relation was found between outcome and number, site or type of treatment used for warts, or for sexual behaviour or orientation of patients. A previously diagnosed sexually transmitted disease (STD) was reported by 34% of men and 28% of women: 28% of men and 23% of women had an STD diagnosed at the time of presentation with warts. No significant relation was found between outcome and STDs past or concurrent, including HIV. Female patients tended to have smaller warts than men but their better outcome remained significant after controlling for the size of warts.Conclusions Treatment outcome for genital warts is poor and significantly predicted by size of warts at presentation. Female patients have a better outcome from treatment of genital warts than male patients.
Schistosomiasis: an unusual cause of pruritus vulvae
Authors: Desmond Noreen , Hanna Nashat , Coker Richard J. , Fish David , Harris John R.W. 
Published: July 2006

AbstractPresentation pruritus vulvae with nodular lesions.Diagnostic pointers foreign travel, cosinophilia, urine microscopy, punch biopsy.Diagnosis vulval sehistosomal granulomas.Outcome responded to praziquantel.
HMB‐45 expression in the epidermis overlying juvenile xanthogranulomas
Authors: Misery Laurent , Boucheron Simone , Claudy Alain L. 
Published: July 2006

AbstractAim HMB‐45 staining of melanocytes has been described in vascular proliferations and surgical scars. We studied this staining on inflammatory tumours.Methods Histiocytic tumors were stained with HMB‐45 monoclonal antibody.Results Only juvenile xanthogranulomas stained with HMB‐45.Conclusion HMB‐45 expression may be induced by cytokines synthesized by inflammatory cells.
Multiple keratoacanthomas in hypertrophic lichen planus: treatment with systemic retinoids (etretinate)
Authors: Paul Maria A. , Stonecipher Marcus R. , Abernethy John , Leshin Barry , White Wain L. , Jorizzo Joseph L. 
Published: July 2006

AbstractA 75‐year‐old woman was referred for treatment of multiple keratoacanthomas and hypertrophic lichen planus. Surgical excision was considered but was not possible given the multiplicity of the lesions. Etretinate, potent topical corticosteroids and gradient support stockings were initiated. Complete resolution was achieved in four months and oral and topical therapy was discontinued. Four months after discontinuation of all therapy there has been no recurrence.
Real hair on the tip of the tongue: a very rare phenomenon
Authors: Laskaris George , Hatziolou Ephtihia , Vareltzidis Antony 
Published: July 2006

AbstractThe occurrence of hair and hair follicles inside the oral cavity is a very rare finding. A review of the literature revealed that only four cases of oral hair have been reported previously. In this article we present an additional case of hair located on the tip of the tongue in a 31‐year‐old white man.
Idiopathic anetoderma with concomitant lesions of the Jadassohn‐Pellizzari and the Schweninger‐Buzzi types
Authors: Haligah Charles E.K. , Zouboulis Christos C. , Abdel‐Naser Mohamed Badawy , Detmar Michael , Ehlers Günther , Gollnick Harald 
Published: July 2006

AbstractAnetoderma is a rare disease of unknown etiology, today classified as a subtype of the circumscribed elastotic disorders. The clinical picture shows atrophic patches located mainly on the upper trunk which characteristically give the palpating finger the sensation of a hernial orifice. Our patient with primary idiopathic anetoderma presented a rarely reported concomitance of the inflammatory type of lesions described by Jadassohn and Pellizzari together with the non‐inflammatory Schweninger‐Buxzi type. Historically and ultrastructurally, both kinds of lesions revealed similar pictures with a scanty perivascular lymphomononuclear cell infiltrate, with rarefied, partly fragmented elastic fibres and normal collagen fibrils. These findings indicate that these two types of lesions represent different stages of the same disease and not a simple association. Furthermore, they support the opinion that the classification of anetoderma into two separate Jadassohn‐Pellixzari and Schweninger‐Buzzi types may he unnecessary. After treatment with oral tetracycline 1 g/day for 3 weeks, no new lesions appeared; however, no improvement of the already present lesions occurred during a 6‐month follow‐up period.
Concomitance of lichen sclerosus et atrophicus and morphea in the same lesions
Authors: Rongioletti F. , Caratti F. , Rebora A. 
Published: July 2006

AbstractA 65‐year‐old woman presented atrophic, slightly indurated plaques on the trunk and a sclerotic, hemorragic plaque on the right forearm. In three biopsies, diagnostic features of both lichen selerosus et atrophicus (LSA) and morphea coexisted. Elastic fibers were absent in the papillary dermis and present in the sclerotic reticular dermis. Although many patients with lesions of both morphea and LSA have been reported, the coexistence of the two histological features in the same lesion is less frequent.
Vulvar cicatricial pemphigoid in a child
Authors: Gürbüz Oya , Khalilazar Rehaleh , Ergun Tüiilin , Yücelten Deniz , Demirçay Zeynep 
Published: July 2006

AbstractCicatricial pemphigoid is a rare disease primarily affecting the elderly. Only a few cases of childhood cicatricial pemphigoid have been reported in the literature. We present a case of cicatricial pemphigoid involving the vulvar region in a child.
Incidence of sexually transmitted diseases amongst a elderly cohort attending a genito‐urinary medicine clinic
Authors: Bergin C. , O'Reilly M. , Goha J. , O'Neill D. , Mulcahy F. 
Published: July 2006

AbstractBackground There is a general perception that sexual interest and activity does not persist into later life, with consequential failure to appreciate the potential prevalence of sexually transmitted diseases in the elderly.Methods Retrospective analysis of case notes of all patients over the age of 65 years who attended a Genito‐Urinary Medicine Clinic: 81 patients were identified over a 6 year period.Results Referral because of positive serology for syphilis accounted for 20% of patients and was the most common reason for presentation. Significantly, another 14% of patients attended for HIV testing. Of the 61 patients whose sexual history was available, 32 had sexual intercourse within the 6 months prior to attendance.Comment This review confirms the need for the medical profession to be more aware of the sexual activity and the possibility of sexually transmitted diseases in this patient group.
Intramuscular gold therapy for young patients with pemphigus vulgaris: a prospective, open, clinical study utilizing a dermatologist/rheumatologist team approach
Authors: Sutej Paul G. , Jorizzo J.L. , White Wain 
Published: July 2006

AbstractPemphigus vulgaris is a severe dermatosis, often requiring systemic corticosteroid therapy. The attempt to find disease‐modifying and corticosteroid‐reducing drugs is ongoing. In this open study, a combined dermatologist‐rheumatologist Learn approach is utilized in attempting to control pemphigus vulgaris with intramuscular gold therapy. Intra‐muscular gold seems to have been a particularly useful agent.
Treatment of psoriasis by dermabrasion
Authors: Zachariae Hugh , Søgaard Helmer 
Published: July 2006

AbstractAim The aim of the study was to utilize the so‐called reversed Köbner phenomenon to treat psoriasis by dermabrasion.Background The background has been reports on long term remissions following other surgical procedures such as dermatomy or laser surgery.Methods 11 psoriatics with localized, chronic heavily infiltrated plaques, which had not responded sufficiently to topical treatment with steroids and/or ditranol or tar, were treated with dermabrasion, using a diamond fraise.Results All treated lesions healed within 3‐4 weeks without recurrence with the exception of a 0.5 X 0.5 cm minor recurrence in one patient. The observation period has been from 6 months to 5 years.Conclusions For this particular group of patients we can recommend dermabrasion as a suitable surgical therapy for psoriasis.
Lymphangioma circumscriptum associated with elephantiasis lymphangiomatosa
Authors: Beard Gwen , Abernethy Lisa , Callen Jeffrey P. 
Published: July 2006

AbstractLymphangioma circumscriptum is a cutaneous entity which may rarely be associated with a deep, visceral lymphangiomatous involvement. We present a child with extensive lower extremity lymphangiomatosis complicated by recurrent cellulitis in combination with diffuse intra‐abdominal disease. Appropriate management of patients with widespread lymphangiomatosis includes initial determination of the extent of involvement and careful selection of therapy for symptomatic areas. Maintenance of skin integrity over lesions of lymphangioma circumscriptum is critical in prevention of recurrent cellutitis which may result in sepsis and even death.
Unprofessional tattoos in Bulgaria – psychological aspects
Authors: Kazandjieva J. , Kamarashev J. , Kadurina M. , Tsankov N. 
Published: July 2006

AbstractBackground People suffered many psychic traumas during the period of the communist rule which altered their perception of the outer world and of themselves. For many their skin became a place where their frustration could be expressed. Up to now the psychological aspects of tattoos in the countries from Eastern Europe have been decidedly understudied.Method We have studied over 100 tattoos, done after the end of World War II in Bulgaria.Aim To examine the motivations for getting tattoos and their symbolic meanings.Conclusions On the ground of motivation three main groups were differentiated. The first group comprises lines and drawings without any meaning or sense, which could be interpreted as a pure form of autoaggression. The second group consisted of symbols of resistance – anticommunist, promonarchic, etc. The closed character of the socialist society brought to life the third group of motives – symbols of the “west” and of the so called “western way of life”. Many of the tattoos observed by us were self‐made and carried an element of self‐inflicted injury.
Awarness to photodamage versus the actual use of sun protection methods by young adults
Authors: Harth Yoram , Schemer Avner , Friedman‐Birnbaum Rachel 
Published: July 2006

AbstractObjective There is accumulating evidence that in spite of the large campaigns against excessive solar exposure undertaken by dermatologists worldwide, children and adolescents are still spending long periods in the sun, and do not follow the recommended sun protection guidelines.The purpose of the present study was to evaluate sun exposure in a group of young Israeli adults and to compare it to their knowledge and application of the various sun protection methods.Methods 202 Caucasian volunteers, (mean age 21.4 ± 2.6), filled out detailed questionnaires on their sun exposure and sun protection habits.Results More than 80% of our study participants are regularly sun exposed for longer than 2 h per day whereas sunscreens are utilized only by 64.9%. Sunscreen use was significantly more prevalent in females than males (81.3% vs. 46.5%). The majority of sunscreen users and nonusers believed that sunscreen could prevent skin cancer (94.3% and 82.0%, respectively) and that these compounds can slow skin aging (90.8% and 76.4% respectively). The understanding of the meaning of the “SPF” was significantly higher in the sunscreen users (85%) than in the nonusers (62.0%). The majority of sunscreen users utilized less than 150 ml of the compound per year which is probably an inadequate amount for a year for full body protection. The two most common reasons for not using sunscreens regularly, were that the application is time consuming, and that sunscreens prevent tanning.Conclusion Our data reveals a discrepancy between a considerably good understanding of the need for sun protection and the still deficient application of these measures especially in young adult males.
Penetration of selected Dead Sea minerals through a healthy rabbit skin, from a sustained‐release transparent varnish, as a prospective treatment for psoriasis
Authors: Shani Jashovam , Sulliman Ahmed , Katzir Itzhak , Brenner Sarah 
Published: July 2006

AbstractBathing in the Dead Sea is an established treatment for psoriasis. Penetration of Dead Sea minerals into psoriatic skin is an effective factor in this treatment, but applying it clinically requires frequent bathing in the Dead Sea or in its bath‐salt solution. We tested an ethyl‐cellulose‐based transparent varnish with a sustained‐release property, for its penetrability of such minerals. Minerals tested were MgBr2, and KBr, known for their relevance in psoriatic proliferation. They were applied for up to three weeks. We could demonstrate that two weekly applications of the salt‐containing varnish on healthy rabbit skin are enough to obtain elevated levels of magnesium and potassium in their plasma. We propose the application of Dead Sea minerals containing varnish as a clinical treatment for psoriasis.
Zygomycotic cellulitis in a renal transplant recipient
Authors: Rotoli Maurizio , La Parola Ilaria Lesnoni , Serino Francesco , Nanni Giuseppe , Citterio Franco , Zannoni Gian Franco , Capelli Arnaldo , Cerimele Decio 
Published: July 2006

AbstractZygomycosis is a rare complication in immunosuppressed patients and is caused predominantly by‐species of Rhizomucor, Absidia and Rhizopus. Lungs and central nervous system localization are the most commonly observed, while skin localization has been observed only in 15% of the patients. We describe a case of zygomycotic cellulitis, with severe edema, inflammatory lesions and a nonimmune bullous eruption, in a renal transplant recipient.
White sponge nevus. Seven cases in the same family
Authors: Rodriguez‐Serna Mercedes , Pérez Amparo , Febrer Isabel , Botella‐Estrada Rafael , Aliaga Adolfo 
Published: July 2006

AbstractSeven cases of white sponge nevus in seven women of the same family are reported. At birth the patients had lesions consisting of asymptomatic white spongy plaques located on the oral mucosa; in two patients the lesions also involved the vaginal mucosa. The lesions improved after antibiotic treatment. Histology was performed in four cases and an ultrastructural study in one. The findings were consistent with the diagnosis of white sponge nevus in all cases. Differential diagnosis was made with other conditions presenting as white lesions of the oral mucosa.
Bacillary angiomatosis in an HIV‐positive patient. Good response to Dapsone
Authors: Fernandez‐Bussy R.A. , Alonso A.B. , Carlson D. , Ramonda S. , Salerni G. , Reeves G. 
Published: July 2006

AbstractObject Report the case of a 25 year old HIV patient who developed bacillary angiomatosis.Setting Department of Dermatology, Centenary Hospital, Rosario, Argentina.Objective The patient tailed to respond to the standard treatment with erythromycin.Result The patient showed improved by the administration of Dapsone along with Zidovudine.Conclusion This case is reported both because it is a rarely seen disease as well as because a good therapeutic response is obtained.
Direct profilometry of the skin: its reproducibility and variability
Authors: Kautzky Florian , Dahm Michael W. , Drosner Michael , Köhler Lars D. , Vogt Hermann‐J. , Borelli Siegfried 
Published: July 2006

AbstractObjective The degree of reproducibility and precision of the mechanical direct profilometry and the intra‐ and interindividual fluctuations of 7 surface parameters were investigated.Material and methods Negative replicas were sampled from defined areas of the skin of 31 volunteers an evaluated with the profile‐tracking device TKC 300 Hommeltester in order to derive data about the inter‐ and intraindividual fluctuations. To determine the precision of this method 6 roughness parameters and J of waviness of each replica were repetitively evaluated. The practicability was tested introducing minimal changes in the experimental set‐up. Further, the effect of urea‐containing creme on the skins topography was investigated in a double‐blind clinical setting on a collective of 11 patients.Results The precision of this method is shown by nearly unchanged topographic parameters. Moreover, our data show smaller intra‐ than interindividual fluctuations of roughness (Ra) and waviness (Wt), being an important demand for clinical investigations.Conclusion In this paper we demonstrate that the parameters of both roughness as well as the recently introduced waviness can be conveniently evaluated with a high degree of precision with the direct profilometry.