bluuebunny/crossref_metadata_2025_split huggingface dataset:
Determinants of investment activity of Russian companies in the real sector under financial constraints.
Authors: Khudko E. V. , Dondopova E. V. 
Published: March 2024

The level of accessibility to various sources of financing plays a crucial rolein formation of an investment strategy. The purpose of the article is to identify and analyse factors influencing the volume of investment expenditures of public Russian enterprises in the real economic sector with consideration to the degree of financial constraints. The research is based on division of companies into more and less financially constrained. The following characteristics were chosen as criteria for segmentation: size, age of the business and placement of corporate bonds on the exchange. A regression analysis specified similarities and differences among determinants of investment activity of more and less financially constrained companies. The key common factor that has an impact on this characteristic of organisations in both groups is investment expenditures of the previous period. Investments of more financially constrained companies have shown a strong dependence on indicators of current cash flow and capital structure. At the same time, the volume of expenses of less financially constrained companies is more influenced by the indicator of accumulated tangible assets. The results of the research may interest enterprises in the real sector when assessing the degree of their financial constraint and determining the volume of investment expenditures.
Potential for industrial production development in the Republic of Bashkortostan and in neighbouring regions
Authors: Aslaeva S. Sh. 
Published: March 2024

Socio-economic development of regions depends on the level of interaction between them on the basis of their industry specialisation. The purpose of the study is to determine the potential for the industrial production development of the regions for further activation of interregional interaction. Types of industrial production of the Republic of Bashkortostan and its neighbouring regions are the object of the study. The paper assesses its development in dynamics and statics by type of activity. Its specialisation is determined, the leading types of economic activity are identified with the use of localisation coefficients and localisation intensity. The development level of industrial production in the Russian Federation and in the regions near the Republic of Bashkortostan have similar trends, however, sharp fluctuations occur in Chelyabinsk and Sverdlovsk regions. In these subjects, the largest share in manufacturing belongs to metallurgical production. Also many activities that are to be in the zone of increased localisation in terms of the turnover of an organisation and the number of employees are actually in the zone of low effective localisation. Industrial production in the Udmurt Republic and the Republic of Tatarstan is less affected by the fluctuations. In Bashkortostan, the largest share is occupied by extraction of coke and petroleum products. To strengthen technological sovereignty, it is necessary to activate the interaction between regions in industrial production.
High genetic diversity but limited gene flow in Flemish populations of the crested newt, Triturus cristatus
Authors: Schön Isa , Raepsaet A. , Goddeeris Boudewijn , Bauwens D. , Mergeay J. , Vanoverbeke J. , Martens Koen 
Published: March 2024

Habitat destruction and fragmentation are among the major causes of amphibian decline. We investigated to what extent geographic distance and barriers affect the genetic composition of the crested newt, Triturus cristatus in Flanders (North Belgium), causing inbreeding or loss of genetic diversity. Data from seven microsatellite loci and 170 individuals from seven metapopulations up to 180km apart revealed heterozygosities of 0.53 to 0.67 within populations and moderate levels of genetic divergence between populations (FST values from 0.074 to 0.141, harmonic means of Dest between 0.070 and 0.189). In all Flemish meta-populations, more than 90% of the individuals from a given geographic region were assigned to the same genetic cluster indicating
little genetic exchange, even in De Panne where the two populations Oosthoek and Westhoek are only a few kilometres apart. Such sub-structuring on a micro-scale has also been described in other amphibians. Unique alleles in most populations further support the probability that genetic drift has already led to some isolation. With the exception of the Oosthoek population, however, we found no significant evidence for bottlenecks. Connectivity within pool clusters seems essential to the maintenance of genetic diversity in crested newts as is indicated by our findings from Tommelen, the population with the largest number of pools in close proximity, which also shows the highest levels of heterozygosity (He and Ho) and the second highest number and richness of alleles. In conclusion, our study indicates that dispersal and migration rates between the Flemish populations of Triturus cristatus are limited at the geographic scale studied here but that habitat fragmentation has not yet led to a significant loss of genetic diversity of the studied Flemish populations, possibly because crested newts are relatively long-lived, fragmentation of their habitat is relatively recent in Flanders, and most investigated pools are still connected at the local scale.
Respon Pupuk N, P, K Dan Pupuk Organik Cair Pada Pertumbuhan Dan Hasil Tanaman Kedelai (Glycine max (L.) Merril)
Authors: Tiara Cinta Septi , Widiwurjani Widiwurjani , Augustien K Nora 
Published: March 2024

Penelitian ini dilaksanakan di Desa Setren Kecamatan Rejoso Kabupaten Nganjuk pada waktu pelaksanaan perlu dicantumkan. Penelitian bertujuan untuk mengetahui dosis pupuk N, P, K dan konsentrasi POC yang tepat serta interaksi antara keduanya terhadap pertumbuhan dan hasil tanaman kedelai. Penelitian ini merupakan Percobaan Faktorial yang disusun berdasarkan Rancangan Acak Kelompok (RAK) dengan 2 faktor perlakuan. Faktor pertama dosis pupuk N, P, K terdiri dari 3 level (100%, 75%, 50%) dan faktor kedua boleh diganti dengan pupuk organik cari terdiri dari 4 level (6 ml/l, 8 ml/l, 10 ml/l, 12 ml/l). Diperoleh 12 kombinasi perlakuan yang masing-masing diulang 3 kali. Hasil penelitian menunjukkan bahwa dosis pupuk N, P, K yang diaplikasi berpengaruh nyata terhadap tinggi tanaman dan jumlah daun umur 21 HST, 28 HST, dan 35 HST, jumlah cabang produktif, dan jumlah polong hampa. Pertumbuhan tanaman kedelai memberikan hasil terbaik pada dosis pupuk N, P, K 75%. Perlakuan konsentrasi POC berpengaruh nyata terhadap tinggi tanaman umur 21 HST, 28 HST, dan 35 HST, jumlah daun umur 21 HST dan 28 HST, serta indeks panen. Pertumbuhan tanaman kedelai memberikan hasil terbaik pada konsentrasi POC 12 ml/l. Terdapat interaksi yang nyata terhadap jumlah polong total per tanaman, jumlah polong isi per tanaman, jumlah polong hampa per tanaman, dan bobot biji per tanaman. Pertumbuhan dan hasil terbaik dijumpai pada kombinasi perlakuan dosis pupuk N, P, K 75% dengan konsentrasi POC 12 ml/l.
Respon Pemberian Beberapa Konsentrasi Pupuk Organik Cair Terhadap Keragaan Pertumbuhan Dan Hasil Tiga Varietas Kacang Tanah (Arachis hypogea L.)
Authors: Rahma Elfiza Dilla , Nilahayati Nilahayati 
Published: March 2024

Kacang tanah merupakan tanaman kacang-kacangan terpenting kedua setelah kedelai yang memiliki nilai ekonomi tinggi. Upaya peningkatan produksi kacang tanah di Indonesia dapat dilakukan antara lain melalui pemupukan menggunakan pupuk organik cair diikuti dengan penanaman varietas unggul. Tujuan penelitian ini adalah untuk mengetahui pengaruh pemberian pupuk organik cair dan beberapa varietas terhadap pertumbuhan dan hasil kacang tanah. Penelitian dilaksanakan di Desa Tambon Tunong Aceh Utara pada bulan Juli-Oktober 2022. Metode yang digunakan dalam penelitian ini adalah Rancangan Acak Kelompok Lengkap Faktorial dengan tiga ulangan. Faktor Pupuk Organik Cair (POC) terdiri dari 4 taraf, P0=0 ml/l, P1=5 ml/l, P2 =10 ml/l, P3=15 ml/l. Faktor varietas terdiri dari 3 taraf, V1= Kancil, V2=Takar 2, V3=Tasia 2. Data yang diperoleh dari penelitian dianalisis dengan menggunakan uji F. Jika terdapat pengaruh yang signifikan maka dilanjutkan dengan uji DMRT 5%. Hasil penelitian menunjukkan bahwa pemberian POC berpengaruh terhadap peubah tinggi tanaman dan jumlah polong per tanaman. Konsentrasi POC 15 ml/l merupakan konsentrasi terbaik dengan tinggi tanaman 56,38 cm, jumlah polong 52,21 polong/tanaman. Faktor varietas hanya berpengaruh terhadap peubah tinggi tanaman, berat biji kering per plot dan produksi. Tasia 2 merupaka varietas dengan pertumbuhan tertinggi yaitu 46,68 cm, sementara produksi terbaik terdapat pada varietas Kancil.
Pengaruh Ekstrak Daun Belimbing Wuluh (Averrhoa bilimbi L.) Terhadap Mortalitas Larva Crocidolomia pavonana F. Pada Tanaman Pakcoy (Brassica rapa L.)
Authors: Riza Juanda Boy , Apriani Rezky , Iswahyudi Iswahyudi 
Published: March 2024

Crocidolomia pavonana merupakan hama penting yang merusak tanaman pakcoy. Hama ini dapat menurunkan hasil produksi tanaman. Untuk memperbaiki hasil produksi dibutuhkan pengendalian terhadap hama ini dengan menggunakan insektisida nabati dari daun belimbing wuluh. Tujuan penelitian ini untuk mengetahui cara pemberian dan konsentrasi ekstrak daun belimbing wuluh terhadap mortalitas larva C. pavonana pada tanaman pakcoy, serta interaksi antara keduanya. Metode yang digunakan adalah Rancangan Acak Lengkap Faktorial, yang terdiri dari 2 faktor, yaitu faktor cara pemberian ekstrak daun belimbing wuluh (P) yang terdiri dari 2 taraf yaitu: P1 = Tetes Topikal dan P2 = Celup Pakan serta faktor konsentrasi ekstrak daun belimbing wuluh (K) yang terdiri dari 5 taraf, yaitu: K0 = Kontrol, K1 = 3,5%, K2 = 5%, K3 = 7,5%, dan K4 = 10%. Hasil Penelitian menunjukkan bahwa cara pemberian celup pakan dengan konsentrasi ekstrak daun belimbing wuluh 10% mampu menyebabkan mortalitas larva sebesar 100% pada 96 Jam Setelah Aplikasi. Ekstrak daun belimbing wuluh dapat digunakan dalam mengendalikan hama C. pavonana.
THE EFFECT OF INFLATION, LABOR FORCE PARTICIPATION RATE AND EXPORTS ON ECONOMIC GROWTH IN INDONESIA
Authors: Nadilla Rizka , Ichsan Ichsan 
Published: March 2024

This study examines the effect of inflation, labor force participation rate and exports on economic growth in Indonesia. This study analyzes the data using the Autoregressive Distributed Lag (ARDL) model with time-series data from 1990 to 2021 obtained from the World Bank and the Central Statistics Agency of Indonesia. The results conclude that in the short and long terminflation has a negative and significanteffect on economic growth in Indonesia. In the short term, labor force participation rate hasa positive and significant effect on economic growth in Indonesia. In the long term, labor force participationrate has a positive but insignificant effect on economic growth in Indonesia. In the shortand longterm, exports have a positive and significant effect on economic growth in Indonesia. Based on the research results, it is suggested that inflation control, improvement in the quality of the labor force, and export enhancement are necessary.
THE EFFECT OF GOVERNMENT INVESTMENT AND SPENDING ON POVERTY IN INDONESIA
Authors: Al-Mahdali Said Munazir , Saharuddin Saharuddin 
Published: March 2024

This study examines and analyzed the effect of Investment and Government Expenditure on Poverty in Indonesia and uses secondary data from 2008 to 2020. The regression model used is a multiple linear regression model and classical methods. assumption test, which consists of a normality test, heteroscedasticity test, multicollinearity test. The regression tool used is Eviews 10. Based on the results of the study, it shows that investment has a negative and significant effect on the number of poor people in Indonesia, while government expenditure has an effect and is significant on the number of poor people in Indonesia and investment and government expenditure have an effect on the number of poor people in Indonesia. The test results for the coefficient of determination show that there is a relationship between the independent and dependent variables of 92.23%, and the remaining 7.77% is influenced by other variables outside this study.
Pendampingan Pencegahan Stunting Dalam Bentuk Pendidikan, Kesehatan dan Kemiskinan Pada Masyarakat Desa Jambo Mesjid Kecamatan Blang Mangat Kota Lhokseumawe
Authors: Anora Ayu , Aminah Sitti , Yusnidar Yusnidar , Darni Surya , Kamaliah Nurul 
Published: March 2024

Upaya penyadaran masyarakat dalam pencegahan stunting dalam bentuk pendidikan, kesehatan dan kemiskinan adalah suatu upaya yang dilakukan untuk meningkatkan kesadaran masyarakat terhadap stunting dengan mengadakan kegiatan pencegahan yang direncanakan oleh Walikota Lhokseumawe, Dinas Kesehatan, Universitas Bumi Persada dan dilaksanakan oleh seluruh masyarakat yang ada di desa Jambo Mesjid Kecamatan Blang Mangat. Upaya penyadaran dalam pencegahan ini dilatar belakangi oleh kurangnya kesadaran masyarakat terhadap bahayanya stunting. Penyebab stunting memiliki banyak faktor multidimensi, salah satunya praktik pengasuhan anak tentang gizi yang kurang baik, termasuk kurangnya pengetahuan ibu, kurangnya pendapatan kepala keluarga, dan rendahnya pendidikan masyarakat. PKM ini bertujuan untuk mengurangi jumlah stunting dari angka 42 balita angka stunting dan terjadi penurunan angka stunting sejumlah 14 balita yang masih menderita stunting. Metode yang digunakan dalam PKM ini yakni metode deskriptif kualitatif dalam menganalisis data. Sampel dalam PKM ini merupakan masyarakat desa Jambo Mesjid yang berjumlah 725 jiwa. Data diperoleh dari penyebaran kuisioner. Hasil yang didapat setelah simulasi terkait pemberian makanan tambahan terhadap balita stunting, pendidikan dibalai pengajian, serta simulasi terkait SDM dalam bidang UMKM dalam taraf peningkatan perekonomian masyarakat desa Jambo Mesjid Kecamatan Blang Mangat. Kata kunci: Pendidikan, Kesehatan, Kemiskinan
The Elephant in the Room: Recognition and Documentation of Personnel Practices That Confound Reproducibility
Authors: Hankenson F Claire 
Published: March 2024

AbstractThe ability to apply findings from animal studies efficiently and effectively is predicated on an understanding of biology and pathobiology, how that biology relates to the human systems being modeled, and how the studies are conducted and reported. This overview discusses various factors in research within the animal environment (referred to as extrinsic factors) that the NIH now expects to be documented to foster replicability in science and expand interpretations of study outcomes. Specifically, an important extrinsic factor in research with animals is that of individual personnel who perform handling practices, participate in research interactions, and share an overall presence in the housing facility with animals, all of which can confound reproducibility efforts in biomedical science. An improved understanding of the influences and behaviors of animal research personnel on animal responses is critical with regard to research results and the interpretation of data collected from animal models of biomedical disease.
ALTERNATIF SOLUSI TERHADAP PERMASALAHAN WARIS SAUDARA LAKI-LAKI YANG MEWARISI BERSAMA DENGAN ANAK PEREMPUAN
Authors: Lubis Zulpahmi , Daulay M. Nur Husein 
Published: March 2024

<p>Persoalan hukum waris saudara laki-laki dari pihak ayah ketika mewarisi bersama dengan anak perempuan kerap berdampak pada ketidak harmonisan dalam hubungan keluarga. Model penelitian ini adalah penelitian kualitatif dengan menggunakan pendekatan yang perundang-undangan, pendekatan kasus, dan pendekatan konseptual serta menggunakan teori mashlat sebagai pisau analisisnya. Hasil kajian penyelesaian pembagian waris antara anak perempuan disaat bersama saudara laki-laki dari pihak ayah yaitu peneliti menawarkan formula hukum sebagai jalan dalam penyelesaian permasalahan yang bukan saja dianggap telah memenuhi nilai keadilan tapi juga sesuai dengan nilai-nilai kemashalatan bersama, yaitu dengan tetap memberikan bagian dari harta peninggalan ayah kepada saudara laki-laki dari anak-anak perempuan melalui jalan shadaqah (yang dalam hal ini peneliti menyebutnya dengan istilah “shadaqah wajibah”), jika bagian saudara laki-laki tidak diberikan akan menimbulkan konflik dan disharmonisasi dalam keluarga. pemberian harta kepada saudara laki-laki dari harta pewaris didasrkan pada nilai kepatutan dan keikhlasan</p><p> </p>
Deferiprone–resveratrol hybrid attenuates iron accumulation, oxidative stress, and antioxidant defenses in iron-loaded human Huh7 hepatic cells
Authors: Li Jin , Koonyosying Pimpisid , Korsieporn Woranontee , Paradee Narisara , Hutachok Nuntouchaporn , Xu Honghong , Ma Yongmin , Chuljerm Hataichanok , Srichairatanakool Somdet 
Published: March 2024

Chronic liver diseases are complications of thalassemia with iron overload. Iron chelators are required to remove excessive iron, and antioxidants are supplemented to diminish harmful reactive oxygen species (ROS), purposing to ameliorate oxidative liver damage and dysfunctions. The deferiprone–resveratrol hybrid (DFP–RVT) is a synthetic iron chelator possessing anti-β-amyloid peptide aggregation, anti-malarial activity, and hepatoprotection in plasmodium-infected mice. The study focuses on investigating the antioxidant, cytotoxicity, iron-chelating, anti-lipid peroxidation, and antioxidant defense properties of DFP–RVT in iron-loaded human hepatocellular carcinoma (Huh7) cells. In the findings, DFP–RVT dose dependently bound Fe(II) and Fe(III) and exerted stronger ABTS•- and DPPH•-scavenging (IC50 = 8.0 and 164 μM, respectively) and anti-RBC hemolytic activities (IC50 = 640 μM) than DFP but weaker than RVT (p &lt; 0.01). DFP–RVT was neither toxic to Huh7 cells nor PBMCs. In addition, DFP–RVT diminished the level of redox-active iron (p &lt; 0.01) and decreased the non-heme iron content (p &lt; 0.01) in iron-loaded Huh7 cells effectively when compared without treatment in the order of DFP–RVT &gt; RVT ∼ DFP treatments (50 µM each). Moreover, the compound decreased levels of hepatic ROS in a dose-dependent manner and the level of malondialdehyde, which was stronger than DFP but weaker than RVT. Furthermore, DFP–RVT restored the decrease in the GSH content and GPX and SOD activities (p &lt; 0.01) in iron-loaded Huh7 cells in the dose-dependent manner, consistently in the order of RVT &gt; DFP–RVT &gt; DFP. Thus, the DFP–RVT hybrid possesses potent iron chelation, antioxidation, anti-lipid peroxidation, and antioxidant defense against oxidative liver damage under iron overload.
A rotary transformer cross-subject model for continuous estimation of finger joints kinematics and a transfer learning approach for new subjects
Authors: Lin Chuang , He Zheng 
Published: March 2024

IntroductionSurface Electromyographic (sEMG) signals are widely utilized for estimating finger kinematics continuously in human-machine interfaces (HMI), and deep learning approaches are crucial in constructing the models. At present, most models are extracted on specific subjects and do not have cross-subject generalizability. Considering the erratic nature of sEMG signals, a model trained on a specific subject cannot be directly applied to other subjects. Therefore, in this study, we proposed a cross-subject model based on the Rotary Transformer (RoFormer) to extract features of multiple subjects for continuous estimation kinematics and extend it to new subjects by adversarial transfer learning (ATL) approach.MethodsWe utilized the new subject’s training data and an ATL approach to calibrate the cross-subject model. To improve the performance of the classic transformer network, we compare the impact of different position embeddings on model performance, including learnable absolute position embedding, Sinusoidal absolute position embedding, and Rotary Position Embedding (RoPE), and eventually selected RoPE. We conducted experiments on 10 randomly selected subjects from the NinaproDB2 dataset, using Pearson correlation coefficient (CC), normalized root mean square error (NRMSE), and coefficient of determination (R2) as performance metrics.ResultsThe proposed model was compared with four other models including LSTM, TCN, Transformer, and CNN-Attention. The results demonstrated that both in cross-subject and subject-specific cases the performance of RoFormer was significantly better than the other four models. Additionally, the ATL approach improves the generalization performance of the cross-subject model better than the fine-tuning (FT) transfer learning approach.DiscussionThe findings indicate that the proposed RoFormer-based method with an ATL approach has the potential for practical applications in robot hand control and other HMI settings. The model’s superior performance suggests its suitability for continuous estimation of finger kinematics across different subjects, addressing the limitations of subject-specific models.
Assessing of case–cohort design: a case study for breast cancer patients in Xinjiang, China
Authors: Wu Mengjuan , Zhang Tao , Gao Chunjie , Zhao Ting , Wang Lei , Sun Gang 
Published: March 2024

ObjectiveTo assess the effectiveness and clinical value of case–cohort design and determine prognostic factors of breast cancer patients in Xinjiang on the basis of case–cohort design.MethodsThe survival data with different sample characteristics were simulated by using Cox proportional risk models. To evaluate the effectiveness for the case–cohort, entire cohort, and simple random sampling design by comparing the mean, coefficient of variation, etc., of covariate parameters. Furthermore, the prognostic factors of breast cancer patients in Xinjiang were determined based on case–cohort sampling designs. The models were comprehensively evaluated by likelihood ratio test, the area under the receiver operating characteristic curve (AUC), and Akaike Information Criterion (AIC).ResultsIn a simulations study, the case–cohort design shows better stability and improves the estimation efficiency when the censored rate is high. In the breast cancer data, molecular subtypes, T-stage, N-stage, M-stage, types of surgery, and postoperative chemotherapy were identified as the prognostic factors of patients in Xinjiang. These models based on the different sampling designs both passed the likelihood ratio test (p&lt;0.05). Moreover, the model constructed under the case–cohort design had better fitting effect (AIC=3,999.96) and better discrimination (AUC=0.807).ConclusionSimulations study confirmed the effectiveness of case–cohort design and further determined the prognostic factors of breast cancer patients in Xinjiang based on this design, which presented the practicality of case–cohort design in actual data.