bluuebunny/crossref_metadata_2025_split huggingface dataset:
Medullary carcinoma of the breast: An association with negative hormonal receptors
Authors: Ponsky Jeffrey L. , Gliga Lucius , Reynolds Sheryl 
Published: February 2007

AbstractThe records of all patients undergoing breast surgery at one institution over a 6‐year period were retrospectively reviewed. Twenty‐two cases were found to meet the criteria for designation as medullary carcinoma of the breast. Estrogen receptor assay was performed in 20 cases and was negative in 75% of these patients; those with positive estrogen receptor asssay had very low values. Progesterone receptor assay was performed in 10 of these patients and was found to be negative in 9. The one positive value was very low. Medullary carcinoma of the breast, in spite of a generally favorable prognosis, shows a consistent relationship with negative hormonal receptors.
Bilateral abdominoinguinal incision
Authors: Nambisan R. N. , Karakousis C. P. 
Published: February 2007

AbstractA successful removal of a very vascular pelvic sarcoma through a bilateral abdominoinguinal incision is presented. The advantages of the incision are that it provides good exposure of the iliac vessels and aids in dissecting the tumor from these vessels. Catheter embolization of the branches supplying the tumor during angiogram helps to decrease vascularity of very vascular tumors.
Carcinosarcoma of the lung with spindle‐cell epithelial component: Report of a case
Authors: Gabriel Juan B. , Ibanez Irene , Kondlapoodi Preetham , Chauhan Prem M. , Hagstrom Jack W. C. 
Published: February 2007

AbstractA case of primary endobronchial carcinosarcoma with predominant spindle cell squamous carcinoma is described. The spindle cell component has not been previously reported as occurring in pulmonary carcinosarcomas. We suggest that this variety of carcinosarcoma closely resembles sarcoma of the lung histologically and emphasize that a distinction between the two neoplasms is important in view of the generally good prognosis of endobronchial carcinosarcomas.
Malignant mesenchymoma of median nerve: Combined nerve sheath sarcoma and liposarcoma
Authors: Shuangshoti Samruay , Benjavongkulchai Sunpetch , Chittmittrapap Soottiporn 
Published: February 2007

AbstractA malignant mesenchymoma consisting of nerve sheath sarcoma and liposarcoma occurred in the right median nerve of a 29‐year‐old man who did not have stigmata of von Recklinghausen neurofibromatosis. It produced pain at the affected part, referred pain to the palm, and weakness of muscles supplied by branches of this nerve. The tumor was first excised 1 month after its initial manifestation, but recurred twice and eventually metastasized to the lung within 19 months. It is suggested that aberrant differentiation of the mesenchymal component of the neural crest, the ectomesenchymal structure, has created this combined sarcoma of nerve sheath and liposarcoma, forming a malignant mesenchymoma.
Branchiogenic carcinoma (Malignant branchioma)
Authors: Rónay P. , Bodó M. , Zemplén B. 
Published: February 2007

AbstractThe authors describe the characteristics of branchiogenic carcinoma as that of a pathological entity on the occasion of reporting four cases. The clinical course of the disease and the cytological and histological features are discussed on the basis of our observations and literature data. The authors stress the importance of careful and repeated clinical examinations, which exclude the possibility of a primary tumor of other localization, in establishing the diagnosis of branchiogenic carcinoma.
Fatty changes and metastases in axillary lymph nodes
Authors: Werbin Nahum 
Published: February 2007

AbstractA variety of pathological changes with clinical and prognostic significance is described in axillary lymph nodes removed at mastectomy. We studied 572 lymph nodes removed from 43 women and 1 man during a radical or modified radical mastectomy performed for carcinoma of the breast. We found that in about one‐third of the specimens some degree of fat infiltration, or changes, was present; metastases were found in either fatty or nonfatty lymph nodes. We conclude that the presence of fat in axillary lymph nodes does not influence implantation of tumor cells from a primary carcinoma of the breast and has to be reported as an anatomic variant.
Fluorescent histochemical demonstration of estrogen and progesterone binding in giant cell tumors of bone: Preliminary observations
Authors: Malawer Martin , Bray Michael , Kass Mary 
Published: February 2007

AbstractHormonal receptors of giant cell tumors (GCTs) have not been previously reported. Five cases of GCT of bone were analyzed for estrogen and progesterone binding. Frozen sections were studied by a histochemical method, using 17‐beta‐6‐CMOBSA‐FITC and 11‐alpha‐hydroxyprogester‐one‐HS‐BSA‐TMRITC. Cytoplasmic fluorescence with estradiol‐BSA‐FITC was seen in stromal cells of all five tumors; three also showed cytoplasmic staining with progesterone‐BSA‐TMRITC. No fluorescence was seen in the giant cells. Two cases were also analyzed by a dextrancoated charcoal cytosol assay. No estrogen or progesterone receptor was detected by cytosol assay. This study suggests that the estrogen and progesterone binding is present in GCT of bone, possible to low‐affinity sites rather than high‐affinity receptors. Further investigation of hormonal receptors of GCTs of bone is warranted.
Assessment of the role of surgery for stage III bronchogenic carcinoma
Authors: Hara Nobuyuki , Ohta Mitsuo , Tanaka Koichi , Ichinose Yukihito , Noge Sazahito , Miyazaki Kazuhiro , Ishimatsu Toyohiro 
Published: February 2007

AbstractIn order to assess the role of surgery for stage III bronchogenic carcinoma, we reviewed our results of 282 patients who were treated with surgical resection or various other therapy modalities. The survival in patients who underwent surgical resection was significantly better than those with nonresectable carcinoma. However, superior survival results were demonstrated only in patients with complete resection. In contrast, the survival in patients with palliative resection was similar to that in patients with exploratory thoracotomy and inoperable carcinoma. On the other hand, all patients with T3N2 lesions died of their disease within two years after surgery even when undergoing complete resection. Thus, we conclude that radical resection should be indicated in patients with T3N0–1 and Tl–2N2 lesions if complete resection is expected.
Combined paraganglioma and glioma of conus medullaris and cauda equina
Authors: Shuangshoti Samruay , Suwanwela Nitaya , Suwanwela Charas 
Published: February 2007

AbstractA mixed paraganglioma and glioma occurred in the conus medullaris and cauda equina of a woman. The tumor was subdural, encapsulated, and vascular. It was first manifested with symptoms and signs of compression of the cauda equina when she was 19 years of age and was excised when she was 24. The tumor was attached to the conus medullaris, the dura mater, and a nerve root of the cauda equina. Striking light and dark cells with an organoid arrangement mingled with a few glial fibrillary acidic protein (GFAP)‐positive neuroglia forming a combined paraganglioma and glioma. Twenty‐three paragangliomas were reported in the literature including the present case. The sex and age of recorded 19 patients demonstrated ten males and nine females with an average age of 46.3 years. Twenty tumors were subdurally situated at the conus medullaris and cauda equina. Three neoplasms were epidural and thoracic in location.
Endodermal sinus tumour of the ovary: Serum alpha fetoprotein dynamics and mmunohistochemical localization of marker in tumour tissue
Authors: Buamah Paul K. 
Published: February 2007

AbstractThe apparent successful treatment of endodermal sinus tumour of ovary is reported. The patient, after surgery and adjuvant chemotherapy, has remained in remission, and the serum alpha fetoprotein has been less than 10 μg/l over a period of 9 months.
Anaesthesia and development of some experimental tumours
Authors: Frid I. A. , Evtjukhin A. I. , Bernstein M. I. , Rudakov V. F. , Dunajevski I. V. , Ostroumova M. N. , Moskalik K. G. 
Published: February 2007

AbstractPresent work is based on the data of experimental studies on the influence of inhalatory (ether, chloroformum, halothane and methoxyfluorane) and intravenous anaesthesia (neurovegetative block and neuroleptoanalgesia) upon the tumour growth and metastasization as well as the level of corticosteronemy in surgical trauma.It has been revealed that the narcosis may change the course of the tumorous process both by means of its action on the endocryne part of the organism‐tumour system and immediately (halothane) due to its cytostatic action.Obviously, anaesthesia may appear one of the factors influencing the results of multifactoral therapy of tumorous diseases.
Late occurrence of malignancy in a ganglioneuroma 19 years following radiation therapy to a neuroblastoma
Authors: Keller Steven M. , Papazoglou Savvas , McKeever Paul , Baker Alan , Roth Jack A. 
Published: February 2007

AbstractNeuroblastoma is a common solid tumor of childhood. Maturation to a ganglioneuroma or regression has been reported to occur spontaneously or following minimal treatment. Malignant degeneration of such a ganglioneuroma is extremely rare. We present a report of a malignant tumor arising in a ganglioneuroma 19 years following abdominal radiation therapy for neuroblastoma.
Metastatic carcinoma in inguinal hernia sac
Authors: Chen Karl T. K. 
Published: February 2007

AbstractA patient with unexplained low back pain, weight loss, and pulmonary infiltrate underwent an inguinal herniorrhapy. Histologic examination of the grossly normal hernia sac revealed metastatic adenocarcinoma. The patient died of cachexia 10 months later. This case observation suggests the necessity of histologic examination of grossly normal hernia sacs.
Unusual presentation of carcinoma of the vermiform appendix: A report of two cases
Authors: Waizbard E. , Michowitz M. , Baratz M. , Papo J. , Stavorovsky M. 
Published: February 2007

AbstractTwo unusual presentations of perforated mucoid adenocarcinoma of the appendix are described. One patient presented with a large periappendicular abscess that extended into the gluteal region, the other with a retroperitoneal abscess and abscesses in the right flank and groin. Recognition of the source of the abscess may be difficult but is essential for the prevention and elimination of the sepsis which may be life‐threatening. The presence of mucin in the drained pus is highly suggestive for perforated bowel carcinoma. A high index of suspicion and the performance of prompt diagnostic procedures may bring early surgical treatment and better results.
Combination chemotherapy for metastatic carcinoma of the ampulla of Vater—report of three cases
Authors: Bukowski R. M. , Hermann R. E. , Theodors A. 
Published: February 2007

AbstractThree patients with metastatic carcinoma of the ampulla of Vater received celiac artery infusion of 5‐fluorouracil, adriamycin, mitomycin‐C, and streptozotocin followed by intravenous administration of the same combination. In two patients with measurable disease, one partial (6.0 months) and one complete response (16.0 + months) occurred. Two out of three patients remain alive at 30.0+ and 21.0+ months. Carcinoma of the ampulla of Vater may be a neoplasm responsive to combination chemotherapy.
High‐dose versus low‐dose CMFP regimen in advanced breast cancer
Authors: Kumar Anand , Khanna N. N. , Pant C. C. , Khanna S. 
Published: February 2007

AbstractFifty cases of advanced breast cancer (stages III and IV) were treated by combination chemotherapy. The study compares the two different dose schedules and toxicities of a combination of cyclophosphamide, methotrexate, 5‐flurouracil, and prednisone. Results are better with high‐dose regimen, though the incidence of toxicity is much as compared to low‐dose schedules, but, considering the beneficial response, the high‐dose schedule is recommended.
Near‐total gastrectomy
Authors: Takagi Hiroshi , Morimoto Takeshi 
Published: February 2007

AbstractTotal gastrectomy has more frequent and serious postoperative complications than subtotal gastrectomy. An esophago‐gastric stoma with a side‐to‐side anastomosis permits a near‐total gastrectomy to be undertaken with virtually the same results as a total gastrectomy. This procedure is used for early gastric cancers that have widely spreading, single or multiple lesions, or lesions near the esophago‐gastric junction, and for the cure or palliative resection of selected patients with advanced gastric cancer.
Lipomatous meningioma associated with cerebral vascular malformation
Authors: Kasantikul Vira , Jan Brown W. 
Published: February 2007

AbstractA unique epileptic patient with intracranial neoplasm is reported in which a meningioma with lipomatous and osseous components was found associated with cerebral arteriovenous malformation at the same location in the right frontal lobe. The development of the leptomeningeal neoplasm may have been influenced by the underlying vascular anomaly. The cerebral arteriovenous malformation and altered hemodynamics also could have induced the sudden onset of clinical seizures, hemiparesis, and unconsciousness.
Scheduling of combination chemotherapy for a murine melanoma, with the subrenal capsular assay
Authors: Raina Suresh , Hill Helene Z. , Hill George J. , Rush Benjamin F. 
Published: February 2007

AbstractThe effect of varying schedules for administration of two drugs, dimethyl triazeno imidazole carboxamide (DTIC) and methylcyclohexyl chloroethyl nitrosourea (MeCCNU), was studied using the Harding‐Passey Mouse melanoma in the subrenal capsular assay. The results of the assay indicate that the responses of the tumor varied depending on the schedule of administration. The best response, with a mean decrease in dimensions of 3.0 ocular micrometer units (± 1.12 SD), was noted with administration of DTIC on day 1 after tumor implantation, followed by MeCCNU on day 2. These results are similar to previously reported data in CD2F1 mice bearing intraperitonal Harding‐Passey melanoma and suggest that the subrenal capsular assay may be of use in determining the best combinations and schedules of administration for treatment of tumors.
Epidemiology of cancer of the cervix in greater bombay
Authors: Jussawalla D. J. , Yeole B. B. 
Published: February 2007

AbstractAn attempt has been made to study in depth the cervical cancer problem in Greater Bombay by undertaking epidemiological investigations to identify its aetiology, by utilising the data collected by the Bombay Cancer Registry. Although cancer of the uterine cervix is found to occur at all ages in Bombay, it is mainly seen during middle age. Its incidence is highest in the Hindu community and lowest in the Parsi. This neoplasm appears to have a strong association with the degree of sexual activity. Thus it is rarely seen in nuns, and commonly found in women who have had multiple sexual partners. There is also a relative preponderance in the poorer, uneducated section of the community. In order to identify the high‐risk groups, a retrospective study was undertaken of proven cases of cancer of the uterine cervix. The results were compared with those of similar controls, equal in number and closely matched for age, religion, and income, in order to examine the risk factors of possible aetiological importance in women with cervical cancer. We have sought to estimate the effects of parity, the age at first marriage and at first delivery. The highest risk was observed in women who had had multiple pregnancies early in life. It is interesting to note that multiparity seems to be an important risk factor in Bombay women, in contrast to the Western experience.
Hemicorporectomy—perioperative management: A case presentation and review of literature
Authors: Shafir M. , Abel M. , Tausk H. , Norton L. , Miller Th. R. , Aufses A. H. 
Published: February 2007

AbstractHemicorporectomy, or translumbar amputation, is a dramatically drastic surgical salvage procedure for patients with uncontrolled locally extensive pelvic‐perineal malignancies. Several successful cases have been reported in the world literature [3–6] and careful perioperative management has been crucial. The case presented is that of a massive recurrent chondrosarcoma of the pelvis with special emphasis on close monitoring and finely tuned supportive care; unusual manifestations of neuroleptic malignant syndrome and of narcotic withdrawal are discussed.
Advanced leiomyosarcoma of the stomach
Authors: Celik Cihangir , Lopez Cecelia , Douglass Harold O. 
Published: February 2007

AbstractRetrospective studies of twelve patients with advanced gastric leiomyosarcomas were undertaken to evaluate radical surgical resection and combined modality treatment with regard to the patient survival and symptom palliation. All but one patient were found to have metastases or involvement of adjacent organs at the initial operation. Despite radical resection, multidrug chemotherapy, and radiation therapy, no patient survived beyond the third year. Patients with objective response to chemotherapy and radiation and chemotherapy had a mean survival of 27 months, while those who did not respond survived only 7 months. The longest survival among untreated group was 8 months. Successful palliation of advanced gastric leiomyosarcoma requires early diagnosis, surgical resection and multimodal therapy.
Small bowel exclusion from the pelvis by a polyglycolic acid mesh sling
Authors: Devereux Dennis F. , Kavanah Maureen T. , Feldman Merrill I. , Kondi Edward , Hull David , O'brien Michael , Deckers Peter J. , Mozden Peter J. 
Published: February 2007

AbstractRadiation enteritis is seen in patients receiving radiation therapy for various pelvic malignancies. Attempts to prevent this have included various surgical as well as nutritional approaches with little success. The use of a polyglycolic acid mesh sling sewn above the pelvic inlet has prevented small bowel descent into the true pelvis in rats and in humans. The technique has been successful in both with no attendant morbidity during an 11‐month follow up. Several patients have received additional doses of radiation therapy that would not have been given if the small bowel were not removed from the area to be irradiated.
Prolonged remission of metastatic malignant fibrous histiocytoma induced by combination chemotherapy
Authors: Clamon Gerald H. , Robinson Robert A. , Olberding Elizabeth B. 
Published: February 2007

AbstractA patient with metastatic malignant fibrous histiocytoma (MFH) achieved a complete remission with polychemotherapy lasting 42+ months. In view of this long‐term survival and two similar prior reports of long‐term survival after aggressive treatment, the goal of therapy for metastatic MFH must be reconsidered.
Results and complications of staging laparotomy in hodgkin's disease
Authors: Wobbes T. , Lubbers E. J. C. , De Pauw B. E. 
Published: February 2007

AbstractBetween 1969 and 1983, 123 patients with Hodgkin's disease underwent a staging laparotomy. The stages of 34 (27%) patients were changed by laparatomy. Twenty‐nine patients (23%) were upstaged, five (4%) down‐staged. The most considerable change was found in stage III. The accuracy of preoperative lymphangiography was 85%. The postoperative complication rate was 15%. There were no operative deaths. The staging laparotomy for Hodgkin's disease is a reliable procedure, and allows less aggressive therapy in selective groups.
The role and value of surgery in metastatic renal adenocarcinoma: A retrospective clinical study of 106 nephrectomized cases
Authors: Appelqvist Pertti 
Published: February 2007

AbstractThe results of treatment of 106 consecutive nephrectomized cases with metastatic renal adenocarcinoma were analyzed. Over 50% of the patients were dead at 1 year and more than 80% at 2 years from the first metastases. The corresponding 5‐year survival rate was 7.3%. Fourteen patients demonstrated a response to radiotherapy, hormonal therapy, cytotoxic drugs, or active specific immunotherapy. The 5‐year survival rate of the responders was 14.3% from the first metastases. The 5‐year survival rate for 22 patients presenting with only one metastasis was 32%. The corresponding figure for patients presenting with multiple metastases was 1%. Complete excision of metastases was possible in 12 patients, whose 5‐year survival rate was 58.3%. All patients with solitary metachronous metastases completely excised lived 5 years or more. It seems that a small number of metastatic renal adenocarcinomas are slow‐growing tumors that may simulate a favorable effect of a therapy, but at the same time such disease with nephrectomy, usually with minor tumor burden, in fact may also react better to the treatment, and this feature can cause difficulties in judging the value of any therapy in metastatic renal adenocarcinoma.
Postoperative adjuvant mediastinal radiation in lung cancerxs
Authors: Steinfeld Alan D. , Glicksman Arvin S. 
Published: February 2007

AbstractPostoperative adjuvant mediastinal radiation therapy was used in a group of 18 patients with advanced (nine Stage 2, nine Stage 3) non‐small cell carcinoma of the lung who had undergone curative resection. All patients had metastases to hilar and/or mediastinal nodes. The disease‐free survival at 2 1/2 years was 55% for Stage 2 patients, suggesting a survival advantage compared to historical controls. No benefit was found in Stage 3 patients. A prospective randomized study of adjuvant radiation in node‐positive patients is indicated.
Neuromuscular hamartoma
Authors: Chen KARL T. K. 
Published: February 2007

AbstractA rare case of neuromuscular hamartoma, a benign tumor composed of well‐differentiated skeletal muscle and nerve fibers, is described and compared with four previously reported cases. The tumor arose in the major peripheral nerves. Three of the five tumors were congenital tumors. A biopsy is essential in establishing the diagnosis. However, the tumor may be left alone if it cannot be separated from the nerve with ease, since spontaneous regression has been documented.
Utility of the abdominoinguinal incision in the resection of lower abdominal tumors
Authors: Karakousis Constantine P. 
Published: February 2007

AbstractThe abdominoinguinal incision provides exposure and renders resectable large tumors located in the lower retroperitoneum, the area of external iliac vessels, and the wall of the pelvis. It is particularly useful for tumors manifesting fixation to these areas.It has been used successfully in 18 patients with malignant tumors and may be expected to increase substantially resectability of tumors in this area and to decrease the need for hemipelvectomy.
The polymorphic apocrine nevus: A study of a unique tumor including carcinoembryonic antigen staining
Authors: Schwartz Robert A. , Rojas‐Corona Rogelio , Lambert W. Clark 
Published: February 2007

AbstractThe apocrine nevus is a rare tumor. We report a 32‐year‐old man with a neck nodule, histologically an apocrine nevus displaying mature and immature apocrine structures in a distinctive pattern. The carcinoembryonic antigen staining was positive intracellularly only in the smaller luminal structures. We have named this unique tumor a polymorphic apocrine nevus.
Dysgerminoma of the ovary
Authors: Jose Baby , Mendoza Enrique , Chu M. , Sharma Subhash 
Published: February 2007

AbstractDysgerminomas of the ovary are rare germ cell tumors. They are more common at puberty. Surgery followed by irradiation has resulted in excellent cure rates in early stages of this disease. This paper is a review of six patients with a diagnosis of dysgerminoma who were treated at the Department of Radiation Oncology, University of Louisville. The controversy on the use of irradiation in Stage Ia tumor is discussed in detail. A review of the literature is also done in this paper.