bluuebunny/crossref_metadata_2025_split huggingface dataset:
A EPISTEMOLOGIA ESPECISTA E O AVANÇO MITIGADO NA PROTEÇÃO DOS ANIMAIS NO BRASIL
Authors: Oliveira Amanda Muniz , Drescher Sophia Wilhelm 
Published: March 2024

Contextualização: Em 2019, foi apresentado na Câmara o Projeto de Lei nº 1.095 que objetivava tornar mais severa a legislação relativa aos maus-tratos dos animais como um todo. Após modificações, o Projeto foi sancionado como a Lei nº 14.064 de 2020, que alterou a Lei de Crimes Ambientais (Lei nº 9.605 de 1998) criando o §1º- A do artigo 32, no intuito de promover um aumento de pena para a prática do crime de maus-tratos a animais, restringindo seu alcance, entretanto, a cães e a gatos, apenas.
Objetivo: O trabalho visa a compreender as motivações pelas quais a Lei nº 14.064 de 2020 restringiu o aumento da pena do crime de maus-tratos a animais apenas a cães e a gatos.
Método: Neste trabalho, foi utilizado o método indutivo, realizado por meio de revisão bibliográfica e análise empírica documental, a partir de uma abordagem qualitativa. Especificamente, procedeu-se à análise do processo legislativo percorrido pelo Projeto de Lei nº 1.095 de 2019, que deu origem à Lei nº 14.064/2020, e, além da leitura e da análise de bibliografia sobre o Direito Animal e os documentos oficiais que compõem o processo legislativo na Câmara dos Deputados e no Senado Federal, foram analisados os conteúdos das reuniões e das audiências públicas realizadas durante o trâmite.
Conclusão: Foi possível concluir que o aumento de pena no crime de maus-tratos foi restrito a cães e a gatos em virtude de uma epistemologia especista, embasada em uma visão de mundo antropocêntrica, que permeia o discurso do legislativo brasileiro.
Policy Brief 12: De-risking of Russian clients: best intentions, unintended consequences
Authors: Boguslavska Kateryna 
Published: March 2024

After the Russian invasion of Ukraine and the wide-reaching sanctions which ensued, many Western financial institutions began to de-risk Russian clients. Dealing with Russian clients, in many cases, has become expensive from a compliance point of view and toxic from the reputational side.
However, the de-risking of unsanctioned Russian individuals may have a significant impact on the fight against financial crime by potentially causing:

an increase in the use of shadow/unregulated channels of moving money;
a withdrawal of funds away from the European zone to sanctioned countries or non-cooperative jurisdictions;
severe burdens on the investigation of financial crimes (especially in relation to Russian assets and investments) and on international cooperation in criminal matters;
increased opportunities for enablers, such as unscrupulous lawyers and accountants, to take advantage of the situation.

This Policy Brief outlines the current situation and suggests how to better manage risk without having a negative impact on the fight against financial crime.
Differentially Expressed Genes in Atopic Dermatitis: Bioinformatics analysis of pooled microarray gene expression datasets in Gene Expression Omnibus
Authors: Jia Danna , Chen Wenqiang , Li Bin 
Published: March 2024

Introduction:
Atopic dermatitis (AD) is a chronic and refractory inflammatory skin disease characterized by relapsing eczematous and pruritic skin lesions. Understanding the specific gene expression patterns associated with AD is crucial for advancing diagnosis and targeted treatment development. Using bioinformatics methods, candidate genes and biological pathways involved in AD pathogenesis were identified based on gene expression profiles in the Gene Expression Omnibus (GEO) database.
Materials and Methods:
A comprehensive analysis of four pooled transcriptomic datasets obtained from the Gene Expression Omnibus (GEO) database were conducted. Differential gene expression analysis was performed using the GEO2R. The differentially expressed genes (DEGs) between lesion skin of AD patients and normal skin of individuals were analyzed using the Gene Ontology (GO) term enrichment analysis, Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway, and protein-protein interaction (PPI) network to explore the functional roles of these genes.
Results:
Among the patient-level gene expression datasets, we identified 133 shared DEGs, consisting of 48 upregulated genes and 85 downregulated genes. GO analyses revealed these DEGs to be significantly enriched in biological processes including inflammatory responses, cytokine-mediated signaling pathway. These DEGs were also enriched in the KEGG pathway, including viral protein interaction with cytokine and cytokine receptor, C-type lectin receptor signaling pathway, cytokine-cytokine receptor interaction, JAK-STAT signaling pathway, and Adipocytokine signaling pathway.
Conclusion:
By comparing with other studies using the same method, we found that in addition to the already confirmed pathways such as inflammatory response, different studies have found changes in different hub genes and metabolic pathways, which prompts us to develop individualized treatments for AD.
Before Warhol: Anthony Kubek and the Problem of Carpatho-Rusyn American Art
Authors: Kupensky Nick 
Published: March 2024

PRZED WARHOLEM. ANTONI KUBEK I ZAGADNIENIE AMERYKAŃSKIEJ SZTUKI KARPACKORUSIŃSKIEJ
Chociaż Andy Warhol jest najbardziej znanym amerykańskim artystą o karpackorusińskim pochodzeniu, to nie był on pierwszy. Niniejszy artykuł dowodzi, że pierwszym wybitnym amerykańskim karpackorusińskim artystą był nieznany dotąd malarz – ksiądz Antoni Kubek (1885–1971), najstarszy syn pisarza Emila Kubeka. Szkolony przez mistrzów szkoły monachijskiej i węgierskiego impresjonizmu, a także w technice plenerowej kolonii artystycznej Nagybánya, Kubek ugruntował swoją estetykę w głównych ośrodkach środkowoeuropejskiego modernizmu i zyskał sławę dzięki obrazom olejnym przedstawiającym miejskie i naturalne pejzaże oraz świeckie i sakralne martwe natury. Po wyemigrowaniu do Ameryki stał się znany dzięki swojemu malarstwu ściennemu o tematyce religijnej, często wykonywanemu anonimowo, które zdobi dziesiątki cerkwi greckokatolickich w Nowym Jorku, New Jersey i Pensylwanii. Wielu karpackorusińskich Amerykanów posiada kopię jego grafiki Ojcze nasz (1911), która przedstawia Modlitwę Pańską. Swoje dziedzictwo w nowym świecie ugruntował także poprzez zilustrowanie wierszy, opowiadań swojego ojca oraz pierwszej powieści napisanej w języku rusińskim Marko Šoltys (1923). Po przejściu na emeryturę w Kalifornii, Kubek kontynuował rozwijanie swoich artystycznych zainteresowań, pomagając szerzyć „ruską wiarę” na wybrzeżu Pacyfiku oraz rozwijając swoje talenty w zakresie ikonografii i portretu. Po śmierci Kubeka jego dorobek artystyczny w dużej mierze został zapomniany, jednak w świetle odkrycia blisko 100 obrazów w czterech prywatnych kolekcjach obecnie możliwe jest napisanie zarówno interpretacyjnej historii jego twórczości, jak i biografii artystycznej pierwszego amerykańskiego karpackorusińskiego artysty.
Comparison of 2-octyl cyanoacrylate with polyester mesh with standard suture and staples in total knee and hip arthroplasty
Authors: Koyama Suguru , Tensho Keiji , Takashimizu Ikkei , Aoki Tetsuhiro , Shimodaira Hiroki , Iwaasa Tomoya , Horiuchi Hiroshi , Saito Naoto , Yuzuriha Shunsuke , Takahashi Jun 
Published: March 2024

Objective: The use of 2-octyl cyanoacrylate with polyester mesh (OCA-M) has become common in total hip and knee arthroplasty (THA, TKA). We aimed to compare the safety and cosmetic outcomes between OCA-M and standard suture techniques and staples, and determine whether OCA-M can safely be used for TKA. Method: Inclusion criteria were patients who underwent THA or TKA from January 2010 to October 2011 (Suture group), November 2011 to August 2013 (Staple group), March 2017 to September 2018 (OCA-M group). Exclusion criteria was loss of imaging data. Complications during hospitalisation (early complication) and after discharge (late complication) were compared in groups. Plastic and orthopaedic surgeons performed cosmetic evaluations with the modified Vancouver Scar Scale (VSS) and Likert scale at three and six months postoperatively and compared in groups. Results: A total of 249 arthroplasties (suture group=88 patients; staple group=94 patients; OCA-M group=67 patients) were included in the study. The OCA-M group had a significantly lower early complication rate than the suture group (p=0.015). For THA, the OCA-M group had a significantly lower total complication rate than the suture group (p=0.048). For TKA, there was no significant difference among the three groups. The complication rate in the OCA-M group showed no significant difference between THA/TKA. With regards to the VSS, the OCA-M group was significantly better for cosmetic qualities than the suture group (p=<0.001, p=0.021 at three and six months, respectively). For the Likert scale, the OCA-M group was also significantly better for cosmetic qualities than the suture group and staple group (suture–OCA-M, p=0.003 (three months), p=<0.001 (six months); staple–OCA-M, p=0.027 (three months)). Conclusion: In this study, the OCA-M complication rate was low compared to suturing and similar to stapling. Moreover, better cosmetic outcomes were achieved compared to suturing and stapling.
Five-year clinical outcomes of scanning carbon-ion radiotherapy for prostate cancer
Authors: Takakusagi Yosuke , Koge Hiroaki , Kano Kio , Shima Satoshi , Tsuchida Keisuke , Mizoguchi Nobutaka , Yoshida Daisaku , Kamada Tadashi , Katoh Hiroyuki 
Published: March 2024

Background
Carbon-ion radiotherapy (CIRT) has been associated with favorable clinical outcomes in patients with prostate cancer. At our facility, all patients are treated using scanning CIRT (sCIRT). We retrospectively analyzed five-year clinical outcomes of prostate cancer treated with sCIRT to investigate treatment efficacy and toxicity.

Methods
In this study, we included 253 consecutive prostate cancer patients treated with sCIRT at the Kanagawa Cancer Center from December 2015 to December 2017. The total dose of sCIRT was set at 51.6 Gy (relative biological effect) in 12 fractions over three weeks. We employed the Phoenix definition for biochemical relapse. The overall survival (OS), biochemical relapse-free (bRF) rate, and cumulative incidence of late toxicity were estimated using the Kaplan–Meier method. Toxicity was assessed using the Common Terminology Criteria for Adverse Events version 4.0.

Results
The median age of the patients was 70 years (range: 47–86 years). The median follow-up duration was 61.1 months (range: 4.1–80.3 months). Eight (3.2%), 88 (34.8%), and 157 (62.1%) patients were in the low-risk, intermediate-risk, and high-risk groups, respectively, according to the D’Amico classification system. The five-year OS and bRF were 97.5% and 93.3%, respectively. The five-year bRF rates for the low-risk, intermediate-risk, and high-risk groups were 87.5%, 93.7%, and 93.4%, respectively (p = 0.7215). The five-year cumulative incidence of Grade 2 or more late genitourinary and gastrointestinal toxicity was 7.4% and 1.2%, respectively.

Conclusion
The results of this study show that sCIRT has a favorable therapeutic effect and low toxicity in the treatment of prostate cancer.
Getting the message across; a realist study of the role of communication and information exchange processes in delivering stroke Early Supported Discharge services in England
Authors: Chouliara Niki , Cameron Trudi , Byrne Adrian , Fisher Rebecca 
Published: March 2024

Background
Stroke early supported discharge (ESD) involves the co-ordinated transfer of care from hospital to home. The quality of communication processes between professionals delivering ESD and external stakeholders may have a role to play in streamlining this process. We explored how communication and information exchange were achieved and influenced the hospital-to-home transition and the delivery quality of ESD, from healthcare professionals’ perspectives.

Methods
Six ESD case study sites in England were purposively selected. Under a realist approach, we conducted interviews and focus groups with 117 staff members, including a cross-section of the multidisciplinary team, service managers and commissioners.

Results
Great variation was observed between services in the type of communication processes they employed and how organised these efforts were. Effective communication between ESD team members and external stakeholders was identified as a key mechanism driving the development of collaborative and trusting relationships and promoting coordinated care transitions. Cross-boundary working arrangements with inpatient services helped clarify the role and remit of ESD, contributing to timely hospital discharge and response from ESD teams. Staff perceived honest and individualised information provision as key to effectively prepare stroke survivors and families for care transitions and promote rehabilitation engagement. In designing and implementing ESD, early stakeholder involvement ensured the services’ fit in the local pathway and laid the foundations for communication and partnership working going forward.

Conclusions
Findings highlighted the interdependency between services delivering ESD and local stroke care pathways. Maintaining good communication and engagement with key stakeholders may help achieve a streamlined hospital discharge process and timely delivery of ESD. ESD services should actively manage communication processes with external partners. A shared cross-service communication strategy to guide the provision of information along to continuum of stroke care is required. Findings may inform efforts towards the delivery of better coordinated stroke care pathways.
A systematic scoping review of health-promoting interventions for contact centre employees examined through a behaviour change wheel lens
Authors: Bell Zoe , Porcellato Lorna , Holland Paula , Morris Abigail , Smith Chloe , Haines Charlotte , Graves Lee 
Published: March 2024

Purpose
Social determinants of health and poor working conditions contribute to excessive sickness absence and attrition in contact centre advisors. With no recent review conducted, the current scoping review is needed to investigate the volume, effectiveness, acceptability, and feasibility of health-promoting interventions for contact centre advisors. This will inform the adoption and implementation of evidence-based practice, and future research.

Methods
Searches conducted across four databases (MEDLINE, PsycInfo, CINAHL, Web of Science) and reference checking in February 2023 identified health-promoting interventions for contact centre advisors. Extracted and coded data from eligible interventions were systematically synthesised using the nine intervention functions of the Behaviour Change Wheel and behaviour change technique taxonomy.

Results
This scoping review identified a low number of high quality and peer-reviewed health-promoting intervention studies for contact centre advisors (28 studies since 2002). Most interventions were conducted in high-income countries with office-based advisors, predominantly using environmental restructuring and training strategies to improve health. Most interventions reported positive effectiveness results for the primary intended outcomes, which were broadly organised into: i) health behaviours (sedentary behaviour, physical activity, smoking); ii) physical health outcomes (musculoskeletal health, visual health, vocal health, sick building syndrome); iii) mental health outcomes (stress, job control, job satisfaction, wellbeing). Few interventions evaluated acceptability and feasibility.

Conclusion
There is little evidence on the effectiveness, acceptability, and feasibility of health-promoting interventions for contact centre advisors. Evidence is especially needed in low-to-middle income countries, and for remote/hybrid, nightshift, older and disabled advisors.
A meta-analysis comparing the efficacy of mineralized collagen-polymethylmethacrylate and polymethylmethacrylate bone cements in the treatment of vertebral compression fractures
Authors: Li Song-feng , Li Xi-yong , Bai Xiao-hui , Wang Yun-lu , Han Peng-fei , Li Hong-zhuo 
Published: March 2024

Purpose
Vertebral compression fractures are often treated with vertebroplasty, and filling the injured vertebrae with bone cement is a key part of vertebroplasty. This meta-analysis was performed to compare the clinical efficacy and safety of mineralized collagen—polymethylmethacrylate (MC-PMMA) and polymethylmethacrylate (PMMA) bone cement in the treatment of vertebral compression fractures by vertebroplasty.

Methods
A computerized search of the published literature on mineralized collagen-polymethylmethacrylate and polymethylmethacrylate bone cement in the treatment of vertebral compression fractures was conducted in the China National Knowledge Infrastructure (CNKI), Wanfang database, PubMed, Embase, and Cochrane Library. The search was carried out from the time the database was created to March 2023 and 2 researchers independently conducted literature searches to retrieve a total of 884 studies, of which 12 were included in this meta-analysis. Cochrane systematic review methods were used to assess the quality of the literature and a meta-analysis was performed using ReviewManager 5.4 software.

Results
The results of the present meta-analysis showed that in postoperative adjacent vertebral fractures [OR = 0.25; 95% CI (0.15, 0.41)], postoperative cement leakage [OR = 0.45; 95% CI (0.30, 0.68)], Oswestry Disability Index (ODI) scores in the first 3 days after surgery [OR = -0.22; 95% CI (-0.42, -0.03)], ODI score at 6–12 months postoperatively [OR = -0.65; 95% CI (-0.97, -0.32)], visual analog scale (VAS) score at 6–12 months postoperatively [OR = -0.21; 95% CI (-0.46, 0.04)], and 1-year postoperative CT values [OR = 5.56; 95% CI (3.06, 8.06)], the MC-PMMA bone cement group was superior to the PMMA bone cement group. However, the differences between the two groups were not statistically different in terms of cement filling time, cement filling volume, operation time, intraoperative bleeding, hospitalization time, postoperative (<1 week, 3–6 months) vertebral body posterior convexity Cobb’s angle, postoperative (<1 week, 6–12 months) vertebral body anterior margin relative height, postoperative (≤3 days, 1–3 months) pain VAS score and postoperative (1–3 months) ODI score.

Conclusions
Compared with PMMA bone cement, the application of MC-PMMA bone cement is advantageous in reducing postoperative complications (adjacent vertebral fracture rate, cement leakage rate), pain relief, and functional recovery in the long-term postoperative period (>6 months), but there is still a need for more high-quality randomized controlled studies to provide more adequate evidence.
Vancomycin and Ustekinumab Combination Therapy in Acute Ulcerative Colitis
Authors: Nguyen Khue M. , Wright Emily K. 
Published: March 2024

ABSTRACT
The role of antibiotics in the treatment of ulcerative colitis is limited. We present a case of a 25-year-old woman who presented with a flare of ulcerative colitis after an episode of infectious gastroenteritis on a background of known primary sclerosing cholangitis. After the flare, she experienced persistent abdominal pain and diarrhea associated with elevated fecal calprotectin and deep rectosigmoid ulcerations on endoscopy. After unsuccessful trials of vedolizumab, infliximab, and tofacitinib, the patient was commenced on ustekinumab, tacrolimus, and oral vancomycin. Tacrolimus was ceased successfully, but while on maintenance ustekinumab therapy, 2 attempts to cease vancomycin resulted in symptom recurrence and rising fecal calprotectin that improved with vancomycin recommencement. To date, the patient has been on vancomycin continuously for 18 months and remains clinically well with colonoscopy demonstrating inactive colitis. This case highlights how vancomycin may be beneficial in the management of treatment-refractory ulcerative colitis as an adjunct to biologic therapy.
Athenaeus of Attaleia on the Elements of Medicine
Authors: Leith David 
Published: March 2024

Abstract
Athenaeus of Attaleia (fl. mid-first century BC) offers a fascinating example of the interest among Graeco-Roman physicians in marking out the boundaries between medicine and philosophy. As founder of the so-called Pneumatist medical sect, he was deeply influenced by contemporary Stoicism. A number of surviving ancient testimonia tell us that he held a distinctive view on the question of how far medicine should analyse the composition of the human body. Rather than having recourse to the Stoic cosmic elements fire, air, earth and water, he maintained that in the context of the medical art, the relevant elements were the elemental qualities hot, cold, wet and dry. This paper is an attempt to pin down Athenaeus’ position on these issues, and his motivations for holding it, despite a number of conflicting and problematic claims in the surviving evidence.
Retrograde infall of the intergalactic gas onto S-galaxy and activity of galactic nuclei
Authors: Khrapov Sergey S. , Khoperskov Alexander V. 
Published: March 2024

Abstract
We present the results of numerical simulations focused on the accretion of intergalactic gas onto a gas-rich S-type disc galaxy. Our investigation explores the conditions favouring the emergence of counterrotating stellar and gaseous components within the galaxy, leading to the inflow of gas towards the central kiloparsec of the galaxy. Notably, we find that the most substantial reservoir of gas, serving as fuel for galactic nucleus activity, resides within the central region during the retrograde infall of gas at an incident angle of approximately

2

0

°

2{0}^{^\circ }

relative to the galactic plane. Departures from this angle significantly diminish the gas flow rate towards the galactic centre. Conversely, the prograde infall of intergalactic gas makes a marginal contribution to the gas content in the central region and cannot supply fuel to the active galactic nucleus. An intriguing characteristic of the observed retrograde impact is the emergence of a rotating polar ring at the galaxy’s periphery, primarily originating from intergalactic gas.
Gender Sensitivity of Teacher Education Curricula in the Republic of Croatia
Authors: Rogošić Silvia , Baranović Branislava 
Published: March 2024

Abstract
The research aims to determine whether and to what extent teacher education curricula in Croatia are gender sensitive and to examine the status of courses dealing with gender-related topics. For this purpose, a qualitative and quantitative analysis of the seven teacher education curricula was conducted. The analysis was based on Bernstein’s theory of classification and framing rules, which explains how control and power over knowledge and curriculum are exercised by selecting knowledge (from scientific disciplines) for the curriculum, design rules, and curriculum implementation. The findings indicate that gender-based knowledge is not given high status and significance as a teaching subject. Gender-related topics are included in teacher education curricula by weak framing and classification rules. While there are several advantages to such a curriculum design, weak classification and framing rules can lead to a lack of compliance in education on gender-related topics. A vague structure can interfere with students’ understanding of basic concepts and their interconnectedness. Students can choose courses based on personal interest rather than necessity and importance. Recommendations are made to achieve a higher level of gender sensitivity in teacher education curricula, which would contribute to better preparation of teachers for the education of children on gender equality.