bluuebunny/crossref_metadata_2025_split huggingface dataset:
Cost-Effectiveness of Late Endovascular Thrombectomy vs. Best Medical Management in a Clinical Trial Setting and Real-World Setting
Authors: Ospel Johanna Maria , Zerna Charlotte , Harrison Emma , Kleinig Timothy J. , Puetz Volker , Kaiser Daniel P. O. , Graham Brett , Yu Amy Y.X. , van Adel Brian , Shankar Jai J. , McTaggart Ryan A. , Pereira Vitor , Frei Donald F. , Kunz Wolfgang G. , Goyal Mayank , Hill Michael D. 
Published: February 2024

ABSTRACT:Background and purpose:To assess cost-effectiveness of late time-window endovascular treatment (EVT) in a clinical trial setting and a “real-world” setting.Methods:Data are from the randomized ESCAPE trial and a prospective cohort study (ESCAPE-LATE). Anterior circulation large vessel occlusion patients presenting > 6 hours from last-known-well were included, whereby collateral status was an inclusion criterion for ESCAPE but not ESCAPE-LATE. A Markov state transition model was built to estimate lifetime costs and quality-adjusted life-years (QALYs) for EVT in addition to best medical care vs. best medical care only in a clinical trial setting (comparing ESCAPE-EVT to ESCAPE control arm patients) and a “real-world” setting (comparing ESCAPE-LATE to ESCAPE control arm patients). We performed an unadjusted analysis, using 90-day modified Rankin Scale(mRS) scores as model input and analysis adjusted for baseline factors. Acceptability of EVT was calculated using upper/lower willingness-to-pay thresholds of 100,000 USD/50,000 USD/QALY.Results:Two-hundred and forty-nine patients were included (ESCAPE-LATE:n = 200, ESCAPE EVT-arm:n = 29, ESCAPE control-arm:n = 20). Late EVT in addition to best medical care was cost effective in the unadjusted analysis both in the clinical trial and real-world setting, with acceptability 96.6%–99.0%. After adjusting for differences in baseline variables between the groups, late EVT was marginally cost effective in the clinical trial setting (acceptability:49.9%–61.6%), but not the “real-world” setting (acceptability:32.9%–42.6%).Conclusion:EVT for LVO-patients presenting beyond 6 hours was cost effective in the clinical trial setting and “real-world” setting, although this was largely related to baseline patient differences favoring the “real-world” EVT group. After adjusting for these, EVT benefit was reduced in the trial setting, and absent in the real-world setting.
Modeling relaxed policies for discontinuation of methicillin-resistant Staphylococcus aureus contact precautions
Authors: Cui Jiaming , Heavey Jack , Lin Leo , Klein Eili Y. , Madden Gregory R. , Sifri Costi D. , Lewis Bryan , Vullikanti Anil K. , Prakash B. Aditya 
Published: February 2024

AbstractObjective:To evaluate the economic costs of reducing the University of Virginia Hospital’s present “3-negative” policy, which continues methicillin-resistant Staphylococcus aureus (MRSA) contact precautions until patients receive 3 consecutive negative test results, to either 2 or 1 negative.Design:Cost-effective analysis.Settings:The University of Virginia Hospital.Patients:The study included data from 41,216 patients from 2015 to 2019.Methods:We developed a model for MRSA transmission in the University of Virginia Hospital, accounting for both environmental contamination and interactions between patients and providers, which were derived from electronic health record (EHR) data. The model was fit to MRSA incidence over the study period under the current 3-negative clearance policy. A counterfactual simulation was used to estimate outcomes and costs for 2- and 1-negative policies compared with the current 3-negative policy.Results:Our findings suggest that 2-negative and 1-negative policies would have led to 6 (95% CI, −30 to 44; P < .001) and 17 (95% CI, −23 to 59; −10.1% to 25.8%; P < .001) more MRSA cases, respectively, at the hospital over the study period. Overall, the 1-negative policy has statistically significantly lower costs ($628,452; 95% CI, $513,592–$752,148) annually (P < .001) in US dollars, inflation-adjusted for 2023) than the 2-negative policy ($687,946; 95% CI, $562,522–$812,662) and 3-negative ($702,823; 95% CI, $577,277–$846,605).Conclusions:A single negative MRSA nares PCR test may provide sufficient evidence to discontinue MRSA contact precautions, and it may be the most cost-effective option.
Bi-global stability of supersonic backward-facing step flow
Authors: Yu Kaikai , Hao Jiaao , Wen Chih-Yung , Xu Jinglei 
Published: February 2024

Supersonic backward-facing step (BFS) flow is numerically studied using direct numerical simulation (DNS) and global stability analysis (GSA) with a free stream Mach number of 2.16 and a Reynolds number of 7.938 × 105 based on the flat-plate length L and free stream conditions. Two-dimensional BFS flow becomes unstable to three-dimensional perturbations as the step height h exceeds a certain value, while no two-dimensionally unstable mode is found. Global instability occurs with the fragmentation of the primary separation vortex downstream of the step. Two stationary modes and one oscillatory unstable mode are obtained at a supercritical ratio of L/h = 32.14, among which the two stationary modes originate from the coalescence of a pair of conjugate modes. The most unstable mode manifests itself as streamwise streaks in the reattached boundary layer, which is similar to that in shock-induced separated flow, although the flow separation mechanisms are different. Without introducing any external disturbances, the DNS captures the preferred perturbations and produces a growth rate in agreement with the GSA prediction in the linear growth stage. In the quasi-steady stage, the secondary separation vortex breaks up into several small bubbles, and the number of streamwise streaks is doubled. A low-frequency unsteadiness that may be associated with the oscillatory mode is also present.
¿Cuántos son los desaparecidos y cuantas las víctimas de la desaparición forzada en la Argentina? Debates político-memoriales e investigación académica
Authors: Crenzel Emilio 
Published: February 2024

ResumenLa cifra de desaparecidos en Argentina motiva debates recurrentes. Durante la última dictadura militar (1976–1983) sus denunciantes elaboraron diversas cifras y estimaciones pero el número de 30 mil desaparecidos adquirió un carácter canónico. Tras retornar la democracia, la Comisión Nacional sobre la Desaparición de Personas registró 8.960 casos. En los años noventa, en un contexto de impunidad, grupos de la sociedad civil elaboraron sus propias cifras y en los dos mil el Estado ofreció nuevos registros. El resurgimiento del negacionismo y la relativización del crimen revitalizaron este debate. Este trabajo historiza las cifras de desaparecidos y víctimas de desaparición forzada elaboradas por diversos actores y propone una aproximación académica sobre el tema. Comprende a estas cifras en su doble dimensión: como fruto de la elaboración de conocimiento sobre las desapariciones y como expresión de los combates por la memoria sobre las violaciones a los derechos humanos sucedidas en el país.
The Enmynveem mammoth and vegetation changes in arctic Chukotka during the Late Quaternary
Authors: Lozhkin Anatoly V. , Anderson P.M. 
Published: February 2024

AbstractMining operations in the Enmynveem valley, northeastern Siberia, exposed a well-preserved right hind leg of Mammuthus primigenius (woolly mammoth), dated to ca. 37,500 cal yr BP. The leg had a fracture that crosscut the midsections of the tibia and fibula. Additional skeletal and soft tissue remains, including two mummified adults (Berezovka, ca. 47,200 cal yr BP; Bolshoi Lyakhovsky, ca. 37,000 cal yr BP), document the presence of mammoths in interior mountain valleys and across both northern and southern coasts of far northeastern Siberia during Marine Isotope Stage (MIS) 3. A mosaic of herb-dominated tundra communities characterized the vegetation of the Enmynveem site during late to middle MIS 3 and MIS 2 (ca. 37,000–17,000 cal yr BP). Shrubs were limited to Salix during the late Pleistocene, whereas Betula also may have been present in sheltered sites during MIS 3. Herb communities remained dominant during the late Pleistocene–Early Holocene transition, although shrub Betula increased during this interval. By ca. 10,200 cal yr BP, the vegetation was Betula–Alnus shrub tundra. Larix and Pinus pumila were established in the valley by ca. 8700 cal yr BP and ca. 5700 cal yr BP, respectively.
ERICHTHO THE DOCTOR? MEDICAL OBSERVATIONS ON LUCAN'S NECROMANTIC EPISODE
Authors: Silva Gabriel A.F. 
Published: February 2024

AbstractThis article aims to offer a fresh analysis of two passages in the extensive necromancy episode in Lucan's Bellum Ciuile: the ritual to reanimate the dead soldier's corpse (6.667–73), and the surgical procedure Erichtho then proceeds to undertake (6.750–7), resembling the practice of a vivisection. The study will focus mostly on the strong connection of magic to medical traditions in antiquity, with a commentary on, and analysis of, these verses through the lenses of medical vocabulary, themes and motifs. It ultimately concludes that Lucan was familiar with the language and characteristics of the medical tradition, enriched his report with them, and was playing with his audience's knowledge of the same.
Entophysalis in the Rhynie chert (Lower Devonian, Scotland): implications for cyanobacterial evolution
Authors: McMahon Sean , Loron Corentin C. , Cooper Laura M. , Hetherington Alexander J. , Krings Michael 
Published: February 2024

AbstractThe ∼407-myr-old Rhynie chert of Scotland contains exquisite body fossils of land plants, animals and microorganisms, which provide our earliest reasonably complete snapshot of a Phanerozoic terrestrial ecosystem. These fossils have been instrumental to our understanding of the ‘greening of the land’, a major transition in the history of the Earth–life system. Among the primary producers preserved in the chert are cyanobacteria, of which only a fraction have been formally described. Here, we report the occurrence of the colony-forming cyanobacterium Eoentophysalis in the Rhynie chert. To our knowledge, this represents the first bona fide record of Entophysalidaceae from any post-Cambrian fossil assemblage or any non-marine fossil assemblage of any age. The Rhynie Eoentophysalis appears remarkably similar in appearance both to modern marine and freshwater Entophysalis ssp. and to Eoentophysalis belcherensis, a shallow-marine fossil from the ∼2 Ga Belcher Group of Canada that is perhaps the oldest convincing cyanobacterium on record. Darkened cell envelopes in the Rhynie Eoentophysalis correspond well with both E. belcherensis and modern Entophysalis, whose cell envelopes often contain the photoprotective brown pigment scytonemin. The occurrence of Eoentophysalis in the Rhynie chert supports previous claims that the fossilisable traits of entophysalid cyanobacteria are evolutionarily static through geological time. These organisms may be such effective generalists that major changes in their environment – in this case, the transition to a fully non-marine habitat – have not imposed significant selection pressure on these traits.
A Helfrich functional for compact surfaces in
Authors: Yao Zhongwei 
Published: February 2024

AbstractLet
$f\;:\; M\rightarrow \mathbb{C}P^{2}$
be an isometric immersion of a compact surface in the complex projective plane
$\mathbb{C}P^{2}$
. In this paper, we consider the Helfrich-type functional
$\mathcal{H}_{\lambda _{1},\lambda _{2}}(f)=\int _{M}(|H|^{2}+\lambda _{1}+\lambda _{2} C^{2})\textrm{d} M$
, where
$\lambda _{1}, \lambda _{2}\in \mathbb{R}$
with
$\lambda _{1}\geqslant 0$
,
$H$
and
$C$
are respectively the mean curvature vector and the Kähler function of
$M$
in
$\mathbb{C}P^{2}$
. The critical surfaces of
$\mathcal{H}_{\lambda _{1},\lambda _{2}}(f)$
are called Helfrich surfaces. We compute the first variation of
$\mathcal{H}_{\lambda _{1},\lambda _{2}}(f)$
and classify the homogeneous Helfrich tori in
$\mathbb{C}P^{2}$
. Moreover, we study the Helfrich energy of the homogeneous tori and show the lower bound of the Helfrich energy for such tori.
Tarantino in the Ottoman Empire: Glorious Viziers, Pulp Fiction, and Scrambled Narratives
Authors: Bouquet Olivier 
Published: February 2024

I wanted to break up the narration, not to be a wise guy, a show guy, but to make the film dramatically better that way. . . . A novelist would think nothing about starting in the middle. And if characters in a novel go back and tell past things, it's not a flashback, it's just telling a story. I think movies should benefit from the novel's freedoms.— Quentin Tarantino1I wrote a prosopography twenty years ago. I published a biography two years ago. In the first case, I offered the collective biography of 282 servants of the late Ottoman period (1839–1909).2 In the second case, I presented the monograph of a grand vizier from the second half of the 18th century, Halil Hamid Pasha (1736–85).3 In the former, I delivered an academic work (stemming from a PhD dissertation) focused on the study of the careers of central and territorial administrators. In the latter, I recounted the rise and fall of the head of the Sublime Porte. A priori, these two books had nothing in common, except that they dealt with pashas. If I mention them together here, it is not to describe the personal evolution of my research. It is to shed some light on an observation that is regularly made, that is, of the inadequacies of the biographical genre in Ottoman history.4 It is to reflect on how to remedy this situation.
Africans and the Soviet Rights Archipelago
Authors: Loyd Thom 
Published: February 2024

AbstractThe history of Soviet “rights defenders” is seemingly well known. Emerging in the 1960s in response to fears of a creeping re-Stalinization, the rights movement was part of the broader dissident milieu that coalesced in the Khrushchev and Brezhnev eras. Drawing on new documents from the Ukrainian KGB, this article broadens the canon of what we consider “Soviet rights talk” by focusing on a group completely ignored in the existing history of Soviet rights defenders: African students. As the article demonstrates, Soviet citizens were not the only people to draw on a discursive repertoire of civil and universal rights to articulate their demands against the Soviet state. By closely examining the letters and petitions activists produced, it becomes clear that African students’ language of rights grew alongside and, in many respects, pre-empted the Soviet rights movement. The article concludes by considering why, despite sharing the same discursive and physical spaces, neither African nor Soviet rights defenders succeeded in building bridges between their respective islands of protest. Examining this failure to build meaningful solidarities demonstrates the value of pursuing the social history of internationalism; it is only in the banality of the everyday that the capacity for Soviet internationalism to create unanticipated frictions and conflicts reveals itself.
Internationalizing the Revolution: Veterans and Transnational Cultures of Memory and Solidarity between Yugoslavia and Algeria
Authors: Đureinović Jelena 
Published: February 2024

AbstractThe article examines the role of memory in Yugoslav exchanges with the postcolonial world, focusing on the agency of Yugoslav war veterans and their involvement with Algeria. During decolonization, Yugoslav institutions and associations stood in solidarity with anti-colonial liberation movements. Former Partisans were critical agents of Yugoslav internationalism, and the memory of the People's Liberation War (Narodnooslobodilački rat, NOR), which dominated the Yugoslav memory culture, played a connecting role in this context. The article focuses on the transnational aspect of the Yugoslav war memory, an intrinsically everyday phenomenon, exploring its exportation and internationalization. Applying the transnational memory framework to relations between Yugoslav Partisans and Algerian mujahideen, the article illuminates the twofold role of memory: as narratives of the shared past, and as the transfer of knowledge in war commemoration. Firstly, Yugoslav veterans identified with the anti-colonial struggle as comparable to their own. This was not only an official political discourse, but was also shared by Yugoslav society at large. Secondly, they engaged in transfers of knowledge in memory work, providing expertise and training to Algerian veterans. The People's Liberation War memory constituted a key aspect of everyday life in Yugoslav state socialism and veterans internationalized it, adding the dimension of personal war memory. The exchanges of knowledge illuminate the transfer from the discursive level of the shared past to the sphere of commemorative policies and practices that reshaped cultures of war remembrance. The article represents a starting point of a global history of the Yugoslav revolution and a transnational history of memory from the perspective of anti-colonial solidarities.
“You Are Not Alone”: Angela Davis and the Soviet Dreams of Freedom
Authors: Matusevich Maxim 
Published: February 2024

AbstractIn the early 1970s, the plight of a charismatic Black American communist and philosophy professor Angela Davis, put on trial in the United States for her alleged involvement in a courtroom shootout in California, galvanized international public opinion. A massive publicity campaign in support of Angela Davis resonated across the globe and drew in millions of volunteers and sympathizers. The nations of the communist bloc, led by the Soviet Union, were particularly active in rallying their citizens in defense of a jailed American radical. In 1970–1972, Davis became a household name throughout the Soviet Union (but also in East Germany, Cuba, Poland, and other socialist nations). The “Free Angela Davis” campaign was unprecedented in scope and left a lasting mark on the collective memory of the citizens of the Soviet Union and its socialist satellites. Such was the impact of this propaganda juggernaut that decades later the image of Angela Davis remained current as a pop-cultural phenomenon across the former Soviet spaces and a symbol of unrealized and often conflicting aspirations towards freedom.
“Like we would help brothers or sisters”? Practising Solidarity with Greek Civil War Refugees in Socialist Czechoslovakia and the GDR in the Shadow of World War II
Authors: Tohma Nikola , Reinke Julia 
Published: February 2024

AbstractThis article investigates the solidarity campaigns supporting refugees from the Greek Civil War (1946–1949) in post-war Czechoslovakia and the emerging German Democratic Republic. Framed as an important bridge between the interwar and later Cold War forms of socialist internationalism, this case sheds light on its transitory character, revealing the narrative shift from anti-fascist to anti-imperialist contexts and the increasingly institutionalized and ritualized solidarity. Thus, not only was practising solidarity already an integral part of post-war socialist regimes, but it also served a variety of functions, contributing to the legitimization and identity of the Eastern bloc. Based on archival documents and press, the article uncovers the deployment of analogical institutional structures employed by both states, thus opening up the sphere of interaction with their citizens, mobilized to become involved in various ways. The two countries, however, departed from different positions, dealing with opposing legacies of the wartime experience, which influenced the motivations employed in their campaigns. Entangled in discourses of guilt, heroism, and victimhood, yet aligned under the proclaimed values of socialist brotherhood and anti-fascism, building internationalist solidarity in both countries worked alongside and even boosted attempts to overcome the obstacle of the Nazi past, both internally and in their mutual relationship. This article thus contributes to a better understanding of how internationalist solidarity functioned as a platform to build bridges – not only towards the “South”, but also within the Eastern bloc.
Environmental predictors of Escherichia coli concentration at marine beaches in Vancouver, Canada: a Bayesian mixed-effects modelling analysis
Authors: Desta Binyam N. , Tustin Jordan , Sanchez J. Johanna , Heasley Cole , Schwandt Michael , Bishay Farida , Chan Bobby , Knezevic-Stevanovic Andjela , Ash Randall , Jantzen David , Young Ian 
Published: February 2024

Abstract
Understanding historical environmental determinants associated with the risk of elevated marine water contamination could enhance monitoring marine beaches in a Canadian setting, which can also inform predictive marine water quality models and ongoing climate change preparedness efforts. This study aimed to assess the combination of environmental factors that best predicts Escherichia coli (E. coli) concentration at public beaches in Metro Vancouver, British Columbia, by combining the region’s microbial water quality data and publicly available environmental data from 2013 to 2021. We developed a Bayesian log-normal mixed-effects regression model to evaluate predictors of geometric E. coli concentrations at 15 beaches in the Metro Vancouver Region. We identified that higher levels of geometric mean E. coli levels were predicted by higher previous sample day E. coli concentrations, higher rainfall in the preceding 48 h, and higher 24-h average air temperature at the median or higher levels of the 24-h mean ultraviolet (UV) index. In contrast, higher levels of mean salinity were predicted to result in lower levels of E. coli. Finally, we determined that the average effects of the predictors varied highly by beach. Our findings could form the basis for building real-time predictive marine water quality models to enable more timely beach management decision-making.
Mapping of morainic complexes and reconstruction of glacier dynamics north-east of Cook Ice Cap, Kerguelen Archipelago (49°S)
Authors: Deline Philip , Linge Henriette , Ravanel Ludovic , Tuestad Talin , Lafite Romain , Arnaud Fabien , Bakke Jostein 
Published: February 2024

AbstractDue to the limited landmasses in the Southern Hemisphere, we must rely on data from sub-Antarctic islands within the Southern Ocean to record historical climate patterns. Over the past few decades, glaciers throughout the Southern Ocean region have experienced a noticeable retreat, especially in the Kerguelen Archipelago, whose glacial landforms offer valuable insights into long-term climate fluctuations. Our comprehensive glacial geomorphological study conducted in its remote north-western region meticulously examines morainic complexes from smaller cirque glaciers and larger outlet glaciers stemming from the Cook Ice Cap. We mapped these landforms to reconstruct historical glacier extents during the Holocene. The surface area of the three main glaciers had decreased in 1962–1964 by only 35% compared to their maximum extents, whereas surface area changes across 12 time intervals spanning from 1962 to 2019 from aerial and satellite imagery reveal a cumulative reduction of 43.5%. Additionally, we modelled changes in glacier thickness and equilibrium-line altitude for the key glaciers at three distinct stages: 1) their maximum extent before 1962, 2) the early 1960s and 3) 2019. This multifaceted analysis contributes valuable insights into the dynamics of Kerguelen's glaciers and the broader implications for understanding past and ongoing climate dynamics in the Southern Hemisphere.