bluuebunny/crossref_metadata_2025_split huggingface dataset:
Evaluation of patient-controlled sedation (PCS) during surgical removal of impacted lower third molars.
Authors: Shoukry Aktham , Bakr Mohamed Magdy , Mekhemer Sameh , Yassin Salah 
Published: February 2025

Objectives: The current study was conducted to evaluate the safety of patient-controlled sedation (PCS) and the efficiency of elastomeric infusion device during surgical removal of impacted lower third molars and its impact on patients regarding level of sedation, patients’ satisfaction and psycho-motor recovery.
Materials and methods:Twenty patients were equally divided into two groups chosen randomly. In both groups, 0.03 mg/kg Midazolam and 0.5 mg/kg Propofol were administered IV as a bolus dose. Group 1 was then given 0.3 mg/kg/hr Ketamine and 1.2 mg/kg/hr Propofol as a maintenance dose delivered through the PCS pump. Group 2 was then given 0.3 µg/kg/hr Fentanyl and 1.2 mg/kg/hr Propofol as a maintenance dose delivered through the PCS pump. For all patients’ surgical procedure were done under local anesthesia. Before going to the operating theatre all patients were instructed about the PCS pump and familiarized with it. Patients in both groups were evaluated for hemodynamic stability, patient's &surgeon's satisfaction, psychomotor recovery and adverse effects.

Results: The results of this study showed no statistical difference between the two groups. The use of different drug combinations in both groups showed hemodynamic stability, patients’& surgeon's satisfaction and rapid psychomotor recovery. None of the patients in both groups suffered from any adverse reactions such as: nausea, vomiting, hallucinations, involuntary movements, or over-sedation.
Conclusion: PCS can be considered as a safe option in minor oral surgeries providing the majority of patients with high satisfaction and relaxation, also providing the surgeons with good operating conditions and the cooperation of the majority of the patients. Fentanyl-Propofol and Ketamine-Propofol combinations were both safe with respect to hemodynamic changes with rapid recovery of psychomotor functions in all patients.
An early breathing disorder in a newborn: Jeune syndrome
Authors: Narter Fatma , Turkoglu Ozlem , Sarbay Hakan , Erguven Muferret 
Published: February 2025

Introduction: Jeune syndrome affects an estimated 1 in 100.000 to 130.000 people. The syndrome causes breathing disorders and upper or lower respiratory tract infections because of thoracic cage which is smaller and narrower than usual.
Case: Here we report a male newborn presented with narrow thoracic cage and short limbs. Radiological evaluation with PA chest graphy showed abnormal short ribs. 3D CT showed decreased antero-posterior diameter of chest cavity, horizontally located round ended ribs, and shallow acetabular cavity. Abdomen ultrasonography detected bilateral small kidneys accompanied by left pelvi-caliectasis and milimetric intraparanchimal liver calcification. Following recurrent lower respiratory tract infections, the baby expired within fourth month. The final diagnosis was Jeune syndrome.
Conclusion: Jeune syndrome is a rare seen congenital anomaly. Radiological evaluation is essential for the diagnosis. Characteristic findings include many skeletal abnormalities on costochondral junctions, clavicles, iliac bones, long bones of the extremities, and phalanges of both hands and feet. About 60% to 70% of children with this condition die from respiratory failure as babies or young children which are the problem. Early diagnosis to decrease mortality is highly dependent on the early diagnosis of this syndrome
Independent Risk Factors for Failure of Nonoperative Management in Patients with Splenic Injury
Authors: Bozdag Zubeyir , Boyuk Abdullah , Turkoglu Ahmet , Ciftci Taner , Uslukaya Omer , Oguz Abdullah , Gumus Metehan 
Published: February 2025

Objective: It is crucial to assess non-operative management (NOM) of risk failures before it is preferred as a management option for treatment of splenic trauma or rupture. The purpose of this study is to investigate the outcome of non-operative management of splenic trauma, and to determine the independent predictive factors effecting NOM failure.
Material and Methods: Seventy-seven patients among all of consecutive patients admitted with splenic trauma between January 2005 and June 2015 were included in the study. The patients were divided into two groups. Group 1: Successfully treated with non-operative management, and Group 2: The failure of non-operative management. Data recorded included patient demographics, vital signs, injury mechanism, Injury Severity Score (ISS), splenic trauma grade, hematologic parameters, Glasgow Coma Scale (GCS), transfusion requirements, and length of hospital stay.
Results: There were 66 (85.7 %) patients in group 1, while only 11 patients (14.3%) in group 2. Mechanism of injury was blunt in seventy-one patients and, penetrating in 6 patients. ISS [Odds Ratio=1.293; 95% CI=1.045-1.601; p=0.018] and blood transfusion [Odds Ratio=2,739; 95% CI= 1.140-6,581; p=0.024] were detected to be an independent predictive factors for the failure of non-operative management. Group 1 has significantly higher hospitalization period (7.73±2.867 vs 6.67±2.289).
Conclusions: Non-operative management failure risk is crucial and higher in patients with high ISS and in patients who require much blood transfusion in first 24 hours. Special attention should be paid to these patients if non-operative management becomes the preferred management option.
The prevalence of celiac disease in healthy school children in Van City, east of Turkey: a screening study using a rapid test
Authors: Ceylan Nesrin , Demiroren Kaan 
Published: February 2025

Objective: Celiac disease is seen by increasing rates in the whole world. It may have a silent course besides having classical symptoms. It may result in serious complications if the diagnosis is delayed such as anemia, fatigue, vitamin K deficiency, excessive bruising and bleeding. The aim of this study is to detect celiac patients who have not been diagnosed yet in healthy school children.
Materials and Methods: Present study performed was in 1003 school children who are between 5-18 years old in Van city, east of Turkey. Celiac disease was investigated via rapid celiac testing (BiocardTM stick test).
Results: Percentages of the cases, 51.2% were female and 48.8% male. Test was positive in two (0.2%) patients. Ten (1%) patients had immunoglobulin A deficiency. In addition to these patients, one patient had been diagnosed as celiac disease beforehand.
Conclusion: The prevalence of celiac disease in Van city, east of Turkey in our study, shows a lower prevalence than in study which performed in our country previously
Prevalance of early repolarization pattern in young healthy men
Authors: Yildirim Tarik Yildirim , Avci Eyup , Yildirim Seda Elcim , Aydin Gokhan , Dolapoglu Ahmet , Gokuc Adil Ozan 
Published: February 2025

Background: Although the early re-polarization pattern known as a benign condition, it can result in idiopathic ventricular fibrillation and sudden cardiac death. In this study, we aimed to evaluate the prevalence of early repolarization pattern in young healthy men.
Methods and Patients: Four hundred fourteen young healthy man were enrolled in the study. PR intervals, QRS durations, QT intervals and corrected QT durations were measured from electrocardiographic records. Early re-polarization pattern was defined as if an elevation J-point was greater than 0,1 mV according to the isoelectrical point.
Results: The prevalence of early repolarization pattern was 23,2 % (n=96). Of these, we found early re-polarization pattern in inferior, lateral and inferolateral leads with 14,7%, 2,2% and 6,3% respectively. There was a significant relation between heart rate and elevation of J point.
Conclusion: The prevalence of early repolarization pattern in young healthy men from Turkey was similar with the previously reported rates from different white populations.
Shoulder ganglion cysts in MRI: accompanying tendon pathologies and labral lesions
Authors: Sahan Mehmet Hamdi 
Published: February 2025

Objective: The aim of this study was to investigate shoulder tendon pathologies and labral lesions that accompanied with ganglion cysts on the shoulder via magnetic resonance imaging (MRI).
Material and Methods: The 893 shoulder MRIs registered in our computer automation system were reviewed retrospectively between January 2014 and December 2018. Thirty-two patients who ganglion cysts observed in three different localizations in MRI were included to our study. Three group were defined as spinoglenoid notch (1st group), paralabral (2nd group), supra acromioclavicular joint (3rd group). The cases age, gender, clinical findings, localization, size and accompanying pathologies were classified. Rotator cuff tendons, the long head of the biceps tendon pathologies and labral lesions were examined.
Results: A total of 32 patients were 16 males (mean age 49±15 years) and 16 females (mean age 54.7±14 years). Groups were consisted 15 cases in 1st group, 12 cases in 2nd group and 5 cases in 3rd group. In all groups with ganglion cysts, rotator cuff pathologies were frequently accompanied. There was no a significant difference between the groups in terms of rotator cuff pathologies (p>0.05). Entrapment neuropathy in group 1, the long head of the biceps tendon and labral lesions in group 2 were frequently associated. This association was statistically significant among the groups. Large-sized cysts were observed in group 3. There was a positive correlation between cyst size and the number of accompanying pathologies in the 1st and 2nd groups (r:0.582, p:0.001).
Conclusion: In symptomatic shoulder ganglion cysts, understanding ganglion cysts, knowing the pathologies accompanied with ganglion cysts may be useful for surgical plan of cases
Assessment of vena cava inferior diameter with ultrasonography in patients undergoing spinal anesthesia and evaluation of postoperative hypotension
Authors: Ozdemir Ahmet , Yilmaz Sinan , Ogurlu Mustafa 
Published: February 2025

Objective: Hypotension frequently occurs during spinal anesthesia and has serious complication that requires early and quick treatment. The goal of this study was to predict the state of fluids in the patient’s body through measurement via ultrasonography of the inferior vena cava diameter (IVCd) prior to administering the spinal anesthesia. This study also intended to investigate the presence or not of a relationship between the ultrasonography IVCd measurements before spinal anesthesia and hypotension.
Material and Methods: A prospective study was performed in which the patients (n:115) were grouped based on their ultrasonography IVC transverse diameter measurements: those with <1.5 cm diameters were categorized as Group 1 (n:22), those having 1.5-2 cm diameter in Group 2 (n:67) and those possessing >2 cm diameter in Group 3 (n:26). The hemodynamic parameters of all the patients were measured.
Results: Hypotension was observed in 23 (20%) patients, particularly in the 5th minute post administration of spinal anesthesia. Hypotension was especially high in Group 1 (52%) compared to Group 2 (34.8%) and Group 3 (13%) (p<0.001).
Conclusion: We concluded that IVCd measurement with ultrasonography is a significant indicator which helps to determine the volumetric status of the patient. However, considering the development of the complication of hypotension post SA, it is felt that the IVC diameter measurement by USG might not always be adequate by itself, and needs to be assessed together with the clinical parameters of old age and presence of chronic diseases.
Antibacterial Activity of Laurus nobilis: A review of literature
Authors: Sırıken Belgin , Yavuz Ceren , Güler Ayhan 
Published: February 2025

The presence of phenolic compounds in spices and herbs, along with the essential oils, has been gaining attention due to their various functions like antioxidant capacity, antimicrobial properties, and flavoring properties. The Bay leaf belongs to Lauraceae family and is endemic in the Mediterranean region. Lauraceae, is an aromatic plant frequently used as a spice in Mediterranean cookery and as a traditional medicine for the treatment of several infectious disease. L. nobilis also belongs to Lauraceae.L. nobilis is aromatic tree, and is 2 m to 10 m high. L.nobilis contains about 1.3% essential oils and polar flavonoids mono, sesquiterpenes, alkoloids, glycosylated flavor-noids, megastigmane and phenolic components. It is known to have various pharmacological effects, including antimicrobial, cytotoxic and immune modulating. Its’ essential oil containg eucalyptol, α-terpinyl acetate, linalool, methyl eugenol, sabinene and carvacrol. The property of every essential oil varies according to the harvest country, altitude, period of sunshine, conditions of harvest. These essential oil contents of L. nobilis are strong antibacterial activity against Gram negative and Gram positive foodorne pathogens (Salmonella, Staphylococcus aureus, Esherichia coli, Listeria monocytogenes like that), spoilage bacteria (Pseudomonas aeroginosa) as well as antifungal effects. The synergy between terpenes (linalool), lactones, oxides (1,8 cineole) and monoterpenes (camphene, alpa-pinene) gives to the essential oil of Laurel a good antibacterial activity. Its essential oils’ various or single chemical compositions at different concentrations have different inhibition mechanisms that can affect a variety of pathogens by changing membrane permeability, denaturing proteins and inhibiting enzymes. The oils are not affecting on existing beneficial intestinal bacteria.
Epidural blood patch for the treatment of post dural puncture headache in pregnant women
Authors: Binici Orhan , Kuyrukluyıldız Ufuk 
Published: February 2025

Objective: Postdural puncture headache (PDPH) is still a considerable problem and it is one of the most common complications of neuro axial anesthesia. Efficiency of the blood patch performed for the patients who developed postdural headache following spinal and combined spinal-epidural anesthesia carried out in our hospital was retrospectively investigated.
Material and Methods: Postdural puncture headache (PDPH) is one of the complications commonly encountered after epidural anesthesia and analgesia with occurring of dural penetration. In this study, efficiency of the epidural blood patch (EBP) was discussed in the patients with postdural puncture headache who did not give response to medical therapy. A total of 55 patients who developed PDPH following caesarean section performed under spinal and combined spinal-epidural anesthesia between January 2009 and January 2014 in Erzincan State Hospital and Erzincan Mengücek Gazi Training and Research Hospital was included in the study.
Results: Among the 1,110 undergone spinal and 1,749 combined regional anesthesia patient, 55 patients have been developed PDHA and 34 patients who did not give response to medical therapy who applied epidural blood patch.
Conclusions: In the cases of PDPHs which don’t give response to medical therapy within 24 hours, EBP should be administered, considering not only the mothers, but also the infants.
Is tubal ligation effective on sexual dysfunction?
Authors: Kara Osman Fadil , Karli Pervin 
Published: February 2025

Objective: Commonly used methods for preventing pregnancy in Turkey are withdrawal (30%), intrauterine device (27.2%), tube ligation (16.7%), condom (15.2), injection (8.9%), and combined oral contraceptive (1.9%). Protection from pregnancy is one of the most important factors affecting women's health. One of the preferred methods to protect against pregnancy is the 16.7% choice of tube ligation. Tube ligation is used as a contraceptive method but this method has some undesirable consequences. Our aim in this study is to investigate whether tubal ligation has effect on sexually dysfunctional and it is related to the process.
Material method: We included in our study 161 patients using tubal ligation and 77 non-prevention methods. We recorded the demographic characteristics of these patients. We applied the fsfi scale. This questionnaire is a scale of sexual function assessment consisting of 19 questions evaluating sexual functions.
Result: We did not find any difference in the total fsfi (female sexual function index) score between the patients who underwent tubal ligation and those who did not. However, we found a significant decrease in sexual desire and satisfaction in the tubal ligation group. In the subgroup analyzes of the fsfi score, results indicate that the correlation bonds with the subgroups of the tubal ligation group was deteriorated.
Conclusion: Tubal ligation is a preferred method for contraception target, and various studies related to the effects on health have been made. Also, this study determined that tubal ligation has no effect on total fsfi scores. However, subgroup work seemed to have an effect on demand and satisfaction. In addition all, the duration of tubal ligation didn’t have any effect on sexual function.
Cyberknife re-irradiation for recurrent glioblastoma multiforme
Authors: Yersal Ozlem 
Published: February 2025

Objective: Treatment of patients with recurrent glioblastoma multiforme (GBM) is challenging. Treatment alternatives include re-operation, chemotherapy and re-irridation. Stereotactic radiosurgery with cyberknife is a good therapeutic approach to deliver high-dose radiation to a definite target volume with minimizing re-irradiation to nearby healthy tissues. This study, evaluated the efficacy of cyberknife treatment in 24 patients with recurrent GBM.
Methods: Total 24 patients with recurrent GBM who received cyberknife treatment in any line of recurrence between the 2011, 2015 were included in this study. A median dose of 30 Gy was applied to each patient.
Results: Median survival was 10.3 months after cyberknife treatment and 23 months after diagnosis. Patients younger than 60 years (4.8 vs 14.2 month; p:0.05) and patients with primary total tumor excision (9.3 vs 4.9 month; p:0.05) had longer overall survival than other patients in univariate analysis but not in multivariate analysis. In this patient population, any other variables predicting longer overall survival could not be found. Treatment was well-tolerated and no severe toxicities observed.
Conclusion: Although limitations exist, our study demonstrates that SRS in terms of cyberknife for recurrent GBM is feasible and well tolerated by patients with low toxicity.
Comparison of serum glutathione peroxidase levels in healthy controls and patients with oral cavity malignancy
Authors: Belli Şeyda , Demir Halit , Kırankaya Ayşegül 
Published: February 2025

Objective: In this study, we investigated the glutathione peroxidase enzyme activity changes in patients with oral cavity malignancies.
Material and Methods: Twenty-five patients with oral cavity malignancy and 24 healthy individuals were included in the study. There was no statistically significant difference between the groups in terms of age, gender and smoking-alcohol consumption habits.
Results: Glutathione peroxidase activity was found to be significantly lower in the blood of patients with oral cavity malignancies than the control group ( 2,238±0,039, p: 0,0001).
Conclusion: The level of glutathione peroxidase in the blood can be used as an important biomarker for the prognosis and to guide to the treatment approaches for the patients with oral cavity malignancy.
In the evaluation of tracheobronchial lesions, MDCT virtual bronchoscopy with fiber optic bronchoscopy comparison
Authors: Unverdi Zeyni , Kervancioglu Resat , Unverdi Sena , Menzilcioglu Mehmet Sait 
Published: February 2025

Objective: The aim of this study is compare multislice CT VB and FOB to assess tracheobronchial lesions with multislace CT VB.
Material and Methods: In the period between September 2012 and August 2013 found indications for bronchoscopy and the total of 44 patients underwent FOB and FOB MDCT-SB were included in the study to be evaluated. All patients underwent VB and/or FOB. In both methods, tracheobronchial tree were divided into 18 separate segments. FOB virtual bronchoscopic findings as the gold standard method to assess the results were considered. Accordingly, positive and negative predictive values of MDCT for VB, sensitivity, selectivity and specificity values were calculated.
Results: Patient ages 1 and 79 (mean: 53 ± 16) of the patients ranged from 7 (16%) female and 37 (84%) were men. In FOB 16 narrowing, 9 congestion, four external compression, 11 mucosal abnormalities were found and in the VB 12 narrowing, 16 obstruction, 8 external compression detected. None of the 11 mucosal findings in the FOB could not be determined in VB. Patients detect in FOB 25 cases were detected in VB; two patients with lesions on the FOB, although not detected in the VB (false negative). In 14 cases both FOB and endoluminal lesion was detected in the VB. FOB lesions not seen in the VB lesion in 5 cases (false positive). According to these values, sensitivity 92%, specificity 73%, positive predictive value (PPV) of 82%, negative predictive value (NPV) 87%, Accuracy: 84%, respectively.
Conclusion: Both mucosal biopsies should not be made to give details because of disadvantages such as virtual bronchoscopy fob is not an alternative for the moment. However tracheobronchial tumor research, interventional bronchoscopic procedures and biopsy guidance, foreign body aspiration of the initial assessment, tracheal injury is evaluation and treatment planning, obstructive lesions of the distal show, stenosis evaluation of endobronchial abnormalities characterization and postoperative follow-up issues of virtual bronchoscopy, constantly evolving detector technology and software when placed through the right indications for routine use will take time, we believe that the rightful place.
ENTREVISTA: REGINA CÉLIA GRANDO
Authors: Grando Regina Célia , Scheffer Nilce Fátima 
Published: February 2025

Esta Entrevista foi realizada com a professora Dra. Regina Célia Grando por e-mail, na data de 11/12/2024. Neste diálogo, ela faz um resgate de sua vida e atuação na Educação e Educação Matemática, desde quando ela ingressou na escola, até constituir-se professora, na Licenciatura em Matemática. Sua vida volta-se à Educação e Educação Matemática, dedicação à pesquisa, extensão e pós-graduação. Nesta entrevista, Regina apresenta um recorte da sua história e trajetória de vida desde a opção pela carreira do magistério para ser professora de Matemática, até a formação de professores de Matemática, caminho que vem seguindo, há muitos anos, pela Educação Matemática, ao lado de pesquisadores e professores, por atuar em cursos de Graduação, Pós-Graduação e na SBEM.