bluuebunny/crossref_metadata_2025_split huggingface dataset:
Plasma treatment of deproteinized bovine bone mineral promotes the formation of sticky bone and improves osteogenesis
Authors: mingzhu chai , feng jiaying , Zhang Ke , Kong Dezhong , Li Xin 
Published: March 2024

Abstract

Background/Objective:
Although deproteinized bovine bone mineral (DBBM) is a popular bone graft material in clinical practice, it has limited ability to maintain local space and osteogenicity in extensive bone defects. In this study, We aim to assess the mechanical properties and osteogenic potential of the sticky bone blocks prepared with oxygen plasma activation of deproteinised bovine bone mineral followed by mixing with injectable platelet-rich fibrin (I-PRF).
Methods
The sticky bone of the experimental and control groups were prepared using oxygen plasma-treated DBBM and untreated DBBM, respectively.We observed the surface structure of the sticky bone blocks by scanning electron microscopy, assessed the mechanical properties of the sticky bone by a tensile testing machine, evaluated the degradation properties by recording the mass of the sticky bone blocks, and detected platelet activation in the sticky bone blocks by flow cytometry. The adhesion and differentiation capacity of sticky bone block extracts to human osteoblasts was examined using an alkaline phosphatase kit and alizarin red staining.
Results
The results showed that the internal fibres of the sticky bone prepared after plasma treatment were more compact and its mechanical properties were significantly improved. Flow cytometry results showed the plasma treatment promoted platelet activation, and cytological experiments confirmed that the oxygen plasma treatment technique promotes the adhesion and differentiation of osteoblasts. These results are of great significance for the application of sticky bone blocks in the field of implantation and guided tissue regeneration.
Conclusion
Sticky bone blocks prepared by mixing oxygen plasma-treated DBBM with I-PRF showed better mechanical and biological properties.
Systematic exploration of the causal relationships among gallstones, cholecystectomy, and 33 types of site-specific cancers: A Mendelian randomization study based on after-meta analysis
Authors: Teng Fei , Tang Youyin , Lu Zhangyu , Chen Zheyu 
Published: March 2024

Abstract
Background and aim:
The association between gallstones/cholecystectomy and cancer remains inconclusive in the current literature. This study aimed to explore the causal connections between gallstones/cholecystectomy and cancer risk by utilizing a bidirectional two-sample multivariable Mendelian randomization (MVMR) approach with Genome-Wide Association Studies (GWAS) data.
Methods
Utilizing GWAS data from the UK Biobank and FinnGen, this research employed MVMR analyses to explore the impact of gallstones and cholecystectomy on the risk of 33 distinct cancer types. Instrumental variables for gallstones and cholecystectomy were carefully selected to ensure robust analyses, and sensitivity and heterogeneity tests were conducted to verify the findings' validity.
Results
MVMR analysis, incorporating data from more than 450,000 individuals for gallstones and cholecystectomy, revealed nuanced associations with cancer risk. Cholecystectomy was associated with a significantly increased risk of nonmelanoma skin cancer (OR = 1.59, 95% CI: 1.21 to 2.10, P = 0.001), while gallstones were linked to a decreased risk of the same cancer type (OR = 0.63, 95% CI: 0.47 to 0.84, P = 0.002). Interestingly, the analysis also suggested that cholecystectomy may lower the risk of small intestine tumors (OR = 0.18, 95% CI: 0.043 to 0.71, P = 0.015), with gallstones showing an inverse relationship, indicating an increased risk (OR = 6.41, 95% CI: 1.48 to 27.80, P = 0.013).
Conclusions
The multivariable Mendelian randomization analysis highlights the differential impact of gallstones and cholecystectomy on cancer risk, specifically for nonmelanoma skin cancer and small intestine tumors. These results underscore the importance of nuanced clinical management strategies and further research to understand the underlying mechanisms and potential clinical implications of gallstone disease and cholecystectomy on cancer risk.
Multiple Noise Reduction for Distributed Acoustic Sensing Data Processing through Densely Connected Residual Convolutional Networks
Authors: Huang Tianye 
Published: March 2024

Abstract

Distributed acoustic sensing (DAS), which utilizes the entire optical fiber as the sensing medium, provides distinct advantages of high resolution, dynamic monitoring, and resistance to high temperatures. This technology finds diverse applications in the seismic exploration, oil survey, and submarine cable monitoring industries. However, DAS signals are susceptible to various kinds of noise, such as horizontal noise, optical noise, random noise, and so on, which significantly degrade the signal-to-noise ratio (SNR), this low SNR is likely to affect some subsequent analyses, such as inversion and interpretation. These mixed noises can pose a serious challenge to noise reduction in the DAS signal. To address this issue, we have developed a supervised learning-based densely connected residual convolutional denoising network (DCRCDNet), which leverages both encoding and decoding processes to extract features and reconstruct DAS data. The encoding and decoding processes enable the network to fully extract the number of features. The design of dense connectivity and residual blocks allow the network to better extract shallow to deep features, which ultimately reconstruct our DAS signal hidden in the noise. In comparison to the traditional filtering method and other deep learning methods, DCRCDNet has great potential for attenuating strong and mixed noise and extracting hidden signals.
A avaliação da aprendizagem durante o ensino remoto imposto pela pandemia da Covid-19
Authors: Lisbôa Cássia do Carmo Andrade , Moreira Maria Cristina do Amaral 
Published: March 2024

O presente artigo tem por objetivo analisar como se deu a avaliação da aprendizagem nos cursos de Licenciatura em Ciências do Instituto Federal de Educação, Ciência e Tecnologia do Rio de Janeiro-IFRJ durante o ensino remoto emergencial, imposto em decorrência da pandemia da Covid-19. Trata-se de um estudo qualitativo que iniciou com uma revisão bibliográfica, onde foi apresentado o panorama da pandemia e os desafios na área da educação, bem como situou a avaliação no contexto da pesquisa. Em seguida, foram destacadas a percepção dos professores que atuam nos cursos de Licenciatura em física e química no IFRJ sobre o assunto. A análise foi realizada a partir de autores como Freire (2014), Hoffman (2003), Luckesi (2008), Perrenoud (2000) e Dantas (2017). Os dados mostraram avanços em relação à avaliação da aprendizagem, uma vez que historicamente, o ensino de ciências tem pautado suas práticas avaliativas em concepções tradicionais de ensino. O uso de instrumentos avaliativos diferenciados em detrimento da prova, o uso de tecnologias no processo de ensino e aprendizagem são questões trazidas na pesquisa que merecem ser discutidas para favorecer a manutenção de tais práticas no contexto presencial, híbrido ou remoto.
Feasibility analysis of the market-oriented construction management model of drainage project based on evolutionary game
Authors: Liu Mengkai , Wang Bo 
Published: March 2024

Abstract

The construction and operational costs of drainage projects are high. Traditional construction management models impose significant financial pressure on the government and reduce stakeholder motivation. Within the market-oriented development context, reforming the construction management model is crucial for breaking the current predicament. This research establishes a framework for the market-oriented construction management model for drainage projects and constructs a behavioral strategy evolutionary game model involving government, drainage management companies, and pollution discharge subjects. Through theoretical analyses and simulations, this research presents recommendations for the implementation of the market-oriented model. The research findings indicate that: (1) the market-oriented model is feasible both theoretically and practically. Pollution rights trading aids pollution discharge subjects in adapting to the market-oriented model. (2) Ensuring sewage charges remain within the interval [P1, P1 + L2 − L1] is crucial for trilateral cooperation. (3) Simulation analysis shows that intensifying policy support, reducing the cost of technological equipment upgrades, enhancing comprehensive income, lowering the pricing of sewage charges, and raising initial selection probability all promote a tendency towards ESS.
A Case Report of Diffuse-type Tenosynovial Giant Cell Tumor as a Calcaneus
Mass: A Diagnostic Challenge
Authors: Wang Zheng , Wang Xiang , Zhang Shutong 
Published: March 2024

Introduction::
Diffuse-type tenosynovial giant cell tumor (D-TGCT) originates from synovial cells in tendon sheaths and bursae and rarely presents as a calcaneal
mass.

Case Report::
A 44-year-old female presented with left heel pain that had persisted for over a year and had worsened over the past six months. A mass was found
on the Lateral radiograph of the calcaneus, which was diagnosed as an aneurysmal bone cyst. Non-contrast computed tomography (CT) and
magnetic resonance imaging (MRI)diagnosed a benign tumor. Based on light microscopy, special stains, and immunohistochemistry, a final
diagnosis of diffuse tenosynovial giant cell tumor (D-TGCT) was rendered.

Results::
D-TGCT is a slow-growing, infiltrative tumor that can form single or multiple masses outside the joint, and can also involve adjacent jointsmainly
affects weight-bearing joints such as the knee, hip, and ankle. However, D-TGCT presents as a calcaneal mass, which poses a diagnostic challenge
for all radiologists.

Conclusion::
A calcaneal mass exhibiting well-defined borders, focal cortical destruction, a sclerotic rim, and T2WI hypointensity, the possibility of D-TGCT
should be considered.
A Case of Nasal Extranodal NK/T-cell Lymphoma of Lower Limb Muscle
Revealed by 18F-FDG PET/CT
Authors: Hu Xianwen , Li Wenxin , Li Dandan , Wang Pan , Cai Jiong 
Published: March 2024

Background::
Extranodal NK/T-cell lymphoma (ENKTCL) is a type of malignant non-Hodgkin’s lymphoma originating from mature T cells and NK cells,
mainly involving the upper aerodigestive tract, including the nasal cavity, nasopharynx, oropharynx, oral cavity, hypopharynx, larynx, and
occasionally the skin, salivary glands, testes, and gastrointestinal tract, but rarely the skeletal muscle.

Case Presentation::
An 82-year-old man presented with redness, swelling, and pain in his right lower limb for 3 months. He was initially diagnosed with cellulitis at
another hospital and was treated conservatively for two weeks without improvement. He underwent a biopsy of the lesioned muscle and
histopathology revealed nasal type ENKTCL. 18F-FDG PET/CT was recommended for the staging of the lymphoma, and the results showed that
except for the muscles of the right lower extremity, no other organs and tissues were involved.

Conclusion::
ENKTCL confined to the muscle of the lower extremity is rare and often initially misdiagnosed as myositis because of red, swollen, heat, and
painful symptoms that resemble inflammation, and in it, higher radiotracer uptake in 18F-FDG PET/CT helps to distinguish it from myositis.
Vulnerability to Cyberattacks and Sociotechnical Solutions for Health Care Systems: Systematic Review
Authors: Ewoh Pius , Vartiainen Tero 
Published: March 2024

Background
Health care organizations worldwide are faced with an increasing number of cyberattacks and threats to their critical infrastructure. These cyberattacks cause significant data breaches in digital health information systems, which threaten patient safety and privacy.

Objective
From a sociotechnical perspective, this paper explores why digital health care systems are vulnerable to cyberattacks and provides sociotechnical solutions through a systematic literature review (SLR).

Methods
An SLR using the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) was conducted by searching 6 databases (PubMed, Web of Science, ScienceDirect, Scopus, Institute of Electrical and Electronics Engineers, and Springer) and a journal (Management Information Systems Quarterly) for articles published between 2012 and 2022 and indexed using the following keywords: “(cybersecurity OR cybercrime OR ransomware) AND (healthcare) OR (cybersecurity in healthcare).” Reports, review articles, and industry white papers that focused on cybersecurity and health care challenges and solutions were included. Only articles published in English were selected for the review.

Results
In total, 5 themes were identified: human error, lack of investment, complex network-connected end-point devices, old legacy systems, and technology advancement (digitalization). We also found that knowledge applications for solving vulnerabilities in health care systems between 2012 to 2022 were inconsistent.

Conclusions
This SLR provides a clear understanding of why health care systems are vulnerable to cyberattacks and proposes interventions from a new sociotechnical perspective. These solutions can serve as a guide for health care organizations in their efforts to prevent breaches and address vulnerabilities. To bridge the gap, we recommend that health care organizations, in partnership with educational institutions, develop and implement a cybersecurity curriculum for health care and intelligence information sharing through collaborations; training; awareness campaigns; and knowledge application areas such as secure design processes, phase-out of legacy systems, and improved investment. Additional studies are needed to create a sociotechnical framework that will support cybersecurity in health care systems and connect technology, people, and processes in an integrated manner.
Improvements in Neoplasm Classification in the International Classification of Diseases, Eleventh Revision: Systematic Comparative Study With the Chinese Clinical Modification of the International Classification of Diseases, Tenth Revision
Authors: Xu Yicong , Zhou Jingya , Li Hongxia , Cai Dong , Zhu Huanbing , Pan Shengdong 
Published: March 2024

Background
The International Classification of Diseases, Eleventh Revision (ICD-11) improved neoplasm classification.

Objective
We aimed to study the alterations in the ICD-11 compared to the Chinese Clinical Modification of the International Classification of Diseases, Tenth Revision (ICD-10-CCM) for neoplasm classification and to provide evidence supporting the transition to the ICD-11.

Methods
We downloaded public data files from the World Health Organization and the National Health Commission of the People’s Republic of China. The ICD-10-CCM neoplasm codes were manually recoded with the ICD-11 coding tool, and an ICD-10-CCM/ICD-11 mapping table was generated. The existing files and the ICD-10-CCM/ICD-11 mapping table were used to compare the coding, classification, and expression features of neoplasms between the ICD-10-CCM and ICD-11.

Results
The ICD-11 coding structure for neoplasms has dramatically changed. It provides advantages in coding granularity, coding capacity, and expression flexibility. In total, 27.4% (207/755) of ICD-10 codes and 38% (1359/3576) of ICD-10-CCM codes underwent grouping changes, which was a significantly different change (χ21=30.3; P<.001). Notably, 67.8% (2424/3576) of ICD-10-CCM codes could be fully represented by ICD-11 codes. Another 7% (252/3576) could be fully described by uniform resource identifiers. The ICD-11 had a significant difference in expression ability among the 4 ICD-10-CCM groups (χ23=93.7; P<.001), as well as a considerable difference between the changed and unchanged groups (χ21=74.7; P<.001). Expression ability negatively correlated with grouping changes (r=–.144; P<.001). In the ICD-10-CCM/ICD-11 mapping table, 60.5% (2164/3576) of codes were postcoordinated. The top 3 postcoordinated results were specific anatomy (1907/3576, 53.3%), histopathology (201/3576, 5.6%), and alternative severity 2 (70/3576, 2%). The expression ability of postcoordination was not fully reflected.

Conclusions
The ICD-11 includes many improvements in neoplasm classification, especially the new coding system, improved expression ability, and good semantic interoperability. The transition to the ICD-11 will inevitably bring challenges for clinicians, coders, policy makers and IT technicians, and many preparations will be necessary.
PRESTASI BELAJAR DITINJAU DARI GAYA PENGAMBILAN KEPUTUSAN KARIR PADA MAHASISWA
Authors: Safitri Hani Muliani 
Published: March 2024

Hasil yang maksimal dalam lingkup karir mahasiswa salah satunya dapat dilihat melalui prestasi belajar. Dalam hal pengambilan keputusan, masing-masing individu memiliki gaya pengambilan keputusan yang berbeda. Tujuan penelitian ini adalah untuk menguji perbedaan prestasi belajar ditinjau dari gaya pengambilan keputusan karir. Penelitian ini dilakukan terhadap 450 mahasiswa Psikologi di Universitas Muhammadiyah Malang. Pengumpulan data dilakukan dengan skala gaya pengambilan keputusan. Dari hasil analisa data diperoleh hasil nilai Pearson Chi-Square sebesar 17,172a dengan nilai signifikansi 0,009. Hasil penelitian menunjukan adanya perbedaan prestasi belajar ditinjau dari gaya pengambilan keputusan karir pada mahasiswa. Hasil analisis juga menunjukan bahwa mahasiswa dengan kategori gaya pengambilan keputusan rasional memiliki prestasi belajar yang paling tinggi dibandingkan dengan gaya pengambilan keputusan intuitif dan dependen.Kata kunci: Karir, prestasi belajar, gaya pengambilan keputusan karirThe ability of making career decision is urgently needed. One of the factual proofs of the previous statement is the students’ learning achievement. Regarding the mater every individual has distinguished styles in making career decision. The study aimed at examining the differences in students’ learning observed by their style in making career decision. This study was conducted to 450 students Psychology Department, University of Muhammadiyah Malang. Further, the data were collected using the scale of decision-making style. The data analysis shoed the Pearson Chi-Square value of 17.172a with the significance value of 0,009. Accordingly, the study revealed the significant differences in students’ learning achievement observed by the styles in making career decision. In addition, it was also found that the students with the rational style in making career decision had the highest learning achievement among those with intuitive and dependent styles of making career decision.Keywords: Career, learning achievement, styles of making career decision
IMPLEMENTASI METODE INTERPOLASI DAN AHP(ANALYTICAL HIERARCHY PROCESS) UNTUK PENERIMAAN PEGAWAI
Authors: Devianto Yudo , Sari Yunita Sartika , Manikam Ratna Mutu 
Published: March 2024

AbstractEvery company, whether public or private, from small, medium to large scale, can depend on information technology to maximize results and simplify operations. The ease and efficiency of the current computerized system can also be applied as a support for decision making in recruiting employees in a department. By conducting a mathematical simulation of the workings of various decision support methods in ranking applicants for placement in a section. Decision support methods that will be used include interpolation and AHP. The results of this study indicate that interpolation is more appropriate to be used to support decisions with needs that require calculations with large benefit values and low costs, while AHP is more appropriate to be used to support decisions that have more attribute variations. The results given better accommodate the decisions to be taken because a one-to-one comparison is made between one criterion and the other. This method is also very appropriate to use if the decision maker does not have a priority on the weight of the assessment to be carried out. However, this method requires quite a long completion step so it will be more difficult to implement because it requires more accuracy in the process of determining logical consistency. Keywords: interpolation, AHP, decision support system AbstrakSetiap perusahaan, baik pemerintah maupun swasta, dari skala kecil, menengah, hingga besar, dapat bergantung pada teknologi informasi untuk memaksimalkan hasil dan mempermudah operasi. Kemudahan dan efisiensi sistem komputerisasi saat ini juga dapat diterapkan sebagai pendukung pengambilan keputusan dalam perekrutan pegawai di suatu departemen. Dengan melakukan simulasi matematis tentang cara kerja berbagai metode pendukung keputusan dalam memeringkat pelamar untuk ditempatkan di suatu bagian. Metode pendukung keputusan yang akan digunakan antara lain Interpolasi dan AHP. Hasil penelitian ini menunjukkan bahwa interpolasi lebih tepat digunakan untuk mendukung keputusan dengan kebutuhan yang membutuhkan perhitungan dengan nilai manfaat yang besar dan biaya yang rendah, sedangkan AHP lebih tepat digunakan untuk mendukung keputusan yang memiliki variasi atribut yang lebih banyak. Hasil yang diberikan lebih mengakomodir keputusan yang akan diambil karena dilakukan perbandingan satu per satu antara kriteria satu dengan kriteria lainnya. Metode ini juga sangat tepat digunakan jika pengambil keputusan tidak memiliki prioritas terhadap bobot penilaian yang akan dilakukan. Namun metode ini memerlukan langkah penyelesaian yang cukup panjang sehingga akan lebih sulit untuk diimplementasikan karena memerlukan ketelitian yang lebih dalam proses penentuan konsistensi logika. Kata Kunci : interpolasi, AHP, system pendukung keputusan
DIAGNOSIS DAN PENDEKATAN TERAPI PASIEN PERITONITIS
Authors: Pramana Okaniawan Putu Enrico , Setyawati Sri Krisna Dewi Ida Ayu 
Published: March 2024

Abstrak
Peritonitis merupakan inflamasi pada peritonium yang terdiri atas membran serosa yang melapisi rongga abdomen dan organ viseral di dalamnya dan merupakan suatu kegawatdaruratan yang dapat disertai dengan sepsis. Etiologi peritonitis bervariasi menurut lokasi geografis dan faktor lingkungan lokal dengan predisposisi genetik. Peritonitis berdasarkan luas infeksinya dibagi menjadi peritonitis lokalisata dan peritonitis generalisata. Sedangkan peritonitis berdasarkan penyebabnya dapat dibagi menjadi peritonitis primer, sekunder, dan tersier. Penyebaran agen infeksi secara hematogen menjadi mekanisme perkembangan peritonitis primer dan difasilitasi oleh gangguan pertahanan imun dari host. Pada pemeriksaan pencitraan, USG dan CT scan abdomen memainkan peran penting dalam diagnosis dan strategi terapeutik. Fokus utama manajemen adalah identifikasi dan pengobatan yang ditargetkan dari agen penyebab melalui antibiotik dan/atau intervensi bedah
Abstract
Peritonitis was an inflammation of the peritoneum which consists of a serous membrane that lines the abdominal cavity and the visceral organs in it and is an emergency that could be accompanied by sepsis. The etiology of peritonitis varies according to geographic location and local environmental factors with a genetic predisposition. Peritonitis based on the extent of infection was divided into localized peritonitis and generalized peritonitis. While peritonitis based on the cause could be divided into primary, secondary, and tertiary peritonitis. Hematogenous spread of infectious agents was the mechanism for the development of primary peritonitis and was facilitated by impaired host immune defense. In imaging studies, ultrasound and CT scan of the abdomen play an important role in the diagnosis and therapeutic strategy. The main focus of management was the identification and targeted treatment of the causative agent through antibiotics and/or surgical intervention.