bluuebunny/crossref_metadata_2025_split huggingface dataset:
Maize Root Exudates Promote Bacillus sp. Za Detoxification of Diphenyl Ether Herbicides by Enhancing Colonization and Biofilm Formation
Authors: Tian Yanning , Zhong Fangya , Shang Na , Yu Houyu , Mao Dongmei , Huang Xing 
Published: April 2024

Diphenyl ether herbicides are extensively utilized in agricultural systems, but their residues threaten the health of sensitive rotation crops. Functional microbial strains can degrade diphenyl ether herbicides in the rhizosphere of crops, facilitating the restoration of a healthy agricultural environment. However, the interplay between microorganisms and plants in diphenyl ether herbicides degradation remains unclear. Thus, the herbicide-degrading strain Bacillus sp. Za and the sensitive crop, maize, were employed to uncover the interaction mechanism. The degradation of diphenyl ether herbicides by strain Bacillus sp. Za was promoted by root exudates. The strain induced root exudate re-secretion in diphenyl ether herbicide-polluted maize. We further showed that root exudates enhanced the rhizosphere colonization and the biofilm biomass of strain Za, augmenting its capacity to degrade diphenyl ether herbicide. Root exudates regulated gene fliZ, which is pivotal in biofilm formation. Wild-type strain Za significantly reduced herbicide toxicity to maize compared to the ZaΔ fliZ mutant. Moreover, root exudates promoted strain Za growth and chemotaxis, which was related to biofilm formation. This mutualistic relationship between the microorganisms and the plants demonstrates the significance of plant-microbe interactions in shaping diphenyl ether herbicide degradation in rhizosphere soils. [Formula: see text] The author(s) have dedicated the work to the public domain under the Creative Commons CC0 “No Rights Reserved” license by waiving all of his or her rights to the work worldwide under copyright law, including all related and neighboring rights, to the extent allowed by law, 2024.
Age and sex Differences in Pediatric Neuropathic Pain and Complex Regional Pain Syndrome
Authors: Mesaroli Giulia , Davidge Kristen M. , Davis Aileen M. , Perruccio Anthony V. , Choy Samantha , Walker Suellen M. , Stinson Jennifer N. 
Published: April 2024

Background:
Age and sex differences may exist in the frequency (incidence, prevalence) or symptoms of neuropathic pain (NP) and complex regional pain syndrome (CRPS) due to biopsychosocial factors (e.g., neurodevelopment, physiological and hormonal changes, psychosocial differences) that evolve through childhood and adolescence.2 Age and sex differences may have implications for evaluating screening and diagnostic tools and treatment interventions.

Objective:
To map the existing literature on pediatric NP and CRPS with respect to age and sex distributions, and age and sex differences in symptomology and frequency.

Methods:
A scoping literature review was conducted. Databases were searched from inception to January 2023. Data were collected on study design, setting, demographics, and age and sex differences in frequency and symptoms.

Results:
Eighty-seven studies were included. Distribution of participants with CRPS (n=37 studies) was predominantly early adolescence (10–14 years) and female sex, while NP (n=42 studies) was most commonly reported throughout adolescence (10–19 years) in both sexes. Forty-one studies examined age and sex differences in frequency; 6 studies reported higher frequency in adolescence. Very few studies (n=11) examined differences in symptomology.

Discussion:
Large epidemiological studies are required to further understand age and sex differences in frequency of pediatric NP and CRPS. Age and sex differences must be considered when evaluating screening and diagnostic tools and treatment interventions to ensure relevance and validity to both sexes and across ages. Validated tools will improve understanding of age- and sex-dependent differences in symptoms, pathophysiology, and psychosocial impact of pediatric NP and CRPS.
The Burden of Occupational Noise-Induced Hearing Loss From 1990 to 2019: An Analysis of Global Burden of Disease Data
Authors: Liu Ce , He Li , Shan Xiaobing , Zhang Ling , Ge Erjia , Zhang Kai , Luo Bin 
Published: April 2024

Objectives:
The relationship between long-term exposure to occupational noise and hearing loss has been extensively documented. We aimed to assess spatial and temporal changes in the burden of occupational noise-induced hearing loss (ONIHL) in 204 countries and territories with varying socio-demographic indexes (SDI) from 1990 to 2019.

Design:
Temporal and spatial trends in age-standardized disability-adjusted life year rates (ASDR) for ONIHL were estimated by sex, age, SDI level, country, and geographic region from 1990 to 2019. We used the Joinpoint model to calculate annual average percentage changes to assess such trends and projected trends in ASDR for ONIHL globally and across different income regions from 2020 to 2044 using an age-period-cohort model. We fitted the relationship between ASDR and SDI, ASDR and healthcare access and quality index, respectively.

Results:
Overall, the global burden of ONIHL has decreased since 1990, especially in middle and lower SDI regions. In 2019, the global ASDR for ONIHL was 84.23 (95% confidence interval: 57.46 to 120.52) per 100,000 population. From 1990 to 2019, the global ASDR for ONIHL decreased by 1.72% (annual average percentage change = −0.05, 95% confidence interval: −0.07 to −0.03). Our projections showed a decreasing trend in the global ONIHL burden until 2044. ASDR and SDI (R = −0.8, p < 0.05), ASDR and healthcare access and quality index (R = −0.75, p < 0.05) showed significant negative correlations.

Conclusions:
The global ONIHL burden has decreased over the past three decades, especially in regions with middle and lower SDI levels. However, the global ONIHL burden still remained severe in 2019, notably among males, the middle-aged and elderly, and regions with lower SDI levels.
Postoperative C5 Palsy after Anterior or Posterior Decompression for Degenerative Cervical Myelopathy
Authors: Bak Alex B. , Moghaddamjou Ali , Alvi Mohammed , Ahn Henry , Farhadi H. Francis , Shaffrey Christopher I. , Nassr Ahmad , Mummaneni Praveen , Arnold Paul M. , Jacobs W. Bradley , Riew K. Daniel , Kelly Michael , Brodke Darrel S. , Vaccaro Alexander R. , Hilibrand Alan S. , Wilson Jason , Harrop James S. , Yoon S. Tim , Kim Kee D. , Fourney Daryl R. , Santaguida Carlo , Massicotte Eric M. , Kopjar Branko , Fehlings Michael G. 
Published: April 2024

Study Design.
Retrospective cohort study of prospectively accrued data.

Objective.
To evaluate a large, prospective, multicentre dataset of surgically treated degenerative cervical myelopathy (DCM) cases on the contemporary risk of C5 palsy with surgical approach.

Summary of Background Data.
The influence of surgical technique on postoperative C5 palsy after decompression for DCM is intensely debated. Comprehensive, covariate-adjusted analyses are needed using contemporary data.

Methods.
Patients with moderate to severe DCM were prospectively enrolled in the multicenter, randomized, Phase III CSM-Protect clinical trial and underwent either anterior or posterior decompression between Jan 31, 2012 and May 16, 2017. The primary outcome was the incidence of postoperative C5 palsy, defined as the onset of muscle weakness by at least one grade in manual muscle test at the C5 myotome with slight or absent sensory disruption after cervical surgery. Two comparative cohorts were made based on the anterior or posterior surgical approach. Multivariate hierarchical mixed-effects logistic regression was used to estimate odds ratios (OR) with 95% confidence intervals (CI) for C5 palsy.

Results.
A total of 283 patients were included, and 53.4% underwent posterior decompression. The total incidence of postoperative C5 palsy was 7.4% and was significantly higher in patients who underwent posterior decompression compared with anterior decompression (11.26% vs. 3.03%, P=0.008). After multivariable regression, the posterior approach was independently associated with greater than four times the likelihood of postoperative C5 palsy (P=0.017). Rates of C5 palsy recovery were comparable between the two surgical approaches.

Conclusion.
The odds of postoperative C5 palsy are significantly higher after posterior decompression compared to anterior decompression for DCM. This may influence surgical decision-making when there is equipoise in deciding between anterior and posterior treatment options for DCM.

Level of Evidence.
Therapeutic Level—II
The Effect of Albumin Administration in Critically Ill Patients: A Retrospective Single-Center Analysis
Authors: Abdelhamid Salim , Achermann Rita , Hollinger Alexa , Hauser Madlaina , Trutmann Maren , Gallacchi Laura , Siegemund Martin 
Published: April 2024

OBJECTIVES:
The aim of this study was to analyze the development of albumin administration in patients admitted to the adult ICU. In addition, we assessed the impact of albumin administration on serum hemoglobin concentration.

DESIGN:
We conducted a retrospective single-center study including all patients who were admitted to the ICU from January 2013 to December 2021 and stayed at least 24 hours.

SETTING:
The study was conducted in an academic hospital (University Hospital Basel, Switzerland).

PATIENTS:
A total of 20,927 admissions were included, of which 3748 received albumin at least once during their ICU stay. To analyze volume expansion, 2006 admissions met the inclusion criteria, namely at least two hemoglobin measurements within 12 hours, one albumin delivery, and experienced no bleeding, dialysis, or transfusions during this period.

INTERVENTIONS:
None.

MEASUREMENTS:
We examined the hemoglobin levels before and after albumin administration and compared them with a matched control group to assess the amount and duration of volume expansion.

MAIN RESULTS:
From 2013 to 2021 the proportion of critically ill patients treated with albumin rose from 5.0% to 32.5%. An overproportioned increase in albumin use could be seen in surgical patients (4.7–47.2%) and in those receiving RBC transfusion (13.7–72.6%). In those patients receiving albumin, a significant drop in hemoglobin of around 5 g/L on average could be observed following treatment with albumin.

CONCLUSION:
Hemodilution was observable for at least 12 hours after albumin administration and may have caused a decrease in hemoglobin concentration of greater than 8 g/L when isooncotic albumin solution (5%, 25 g in 500 mL) was administered. This makes albumin, especially in its isooncotic form, an ideal colloid to achieve long-lasting volume expansion. However, RBC transfusions may increase under albumin therapy, as transfusion thresholds may be undershot after albumin administration.
Perfluorocarbon Liquid-Silicone Oil Exchange: The Simplicity and Reliability of the Single Port Technique and a Review of Literature
Authors: Silpa-archa Sukhum , Nganthavee Variya 
Published: April 2024

Purpose:
To report the “Single Port Technique” for perfluorocarbon liquid (PFCL)-silicone oil (SO) exchange for the management of giant retinal tear detachments (GRTD).

Methods:
The previously reported techniques of direct PFCL-SO exchange used 2 ports to achieve the influx and outflux of fluid. The term 'Single Port' refers to the use of only one port as the exclusive port for the inflow of SO and the outflow of fluid meniscus and PFCL, performed alternately. This technique is proposed, with illustrated instructions and a surgical video.

Results:
The newly proposed “Single Port Technique” offers a straightforward step using a switch between active aspiration by the vitreous cutter and active silicone oil injection through a single port without the need for assistance. This method has been performed by the authors on 29 patients, including 22 GRTD patients and 7 patients with rhegmatogenous retinal detachment caused by dialysis, and it has demonstrated its simplicity and reliability for use with only standard vitrectomy tools and machine settings.

Conclusion:
The Single Port Technique for PFCL-SO exchange for the management of GRTD and rhegmatogenous retinal detachment caused by dialysis has been tried and tested, and it is a valuable tool that can be easily used by any vitreoretinal surgeon.
The Significance of Screening Family Members in Glaucoma: Opportunities and Challenges
Authors: Bhargava Siddharth , Mason Lauren , Okeke Constance 
Published: April 2024

Precis:
This article delves into the imperative of screening family members of patients with glaucoma due to the disease’s hereditary nature. It discusses the significant risks faced by first-degree relatives, approaches for identification, and challenges in implementing effective screening strategies. Emphasizing education, targeted campaigns, community involvement, and collaborative healthcare approaches, the article highlights the potential for mitigating undiagnosed glaucoma cases through strategic interventions targeting high-risk individuals.

Purpose:
This article underscores the importance of screening family members of glaucoma patients, emphasizing the hereditary nature of the disease and the potential for screening to allow for early intervention to help prevent unnecessary vision loss.

Methods/Results:
Glaucoma, affecting over 111.8 million by 2040, is relatively asymptomatic until late in the disease. Genetics predispose to glaucoma, with up to 70% heritability. High-risk individuals, particularly first-degree relatives, exhibit substantially elevated glaucoma risks—up to 22% compared with 2.3% in controls. Family history also correlates with greater disease severity. Identifying high-risk family members through cascade screenings for causative genes or direct examinations during proband visits emerges as efficient strategies. Challenges persist, including slow progression, healthcare accessibility, and ethical dilemmas in implementing family member screening. Challenges extend to the healthcare system, socioeconomic barriers, and familial communication issues. Efforts to educate probands and the public on the hereditary nature of glaucoma are pivotal. Tailored education campaigns, leveraging clinic visits, and community screenings, complemented by optometrist collaboration, form essential strategies.

Conclusions:
Although challenges hinder family member screening, educating probands, targeted patient education, collaborative healthcare approaches, and community involvement offer promising avenues to combat undiagnosed glaucoma cases.
The Purpose, Process, and Advancement of Forensic Nursing Standards
Authors: Williams Joyce P. , Downing Nancy , Miyamoto Sheridan 
Published: April 2024

ABSTRACT

Background
To strengthen the nation's use of forensic science and advance professional practice, forensic practitioners and scientists in the Organization of Scientific Area Committees (OSAC) develop standards in forensic science. The Forensic Nursing Subcommittee was created by OSAC in 2021 to develop standards that improve patient outcomes through delivery of consistent practice guidelines, evidence-based techniques for preservation of evidence, and accurate representation of practice and examination findings.

Purpose
The purpose of this article is to relate the history of forensic science standard development in the United States, discuss the rationale for forensic nursing standards, and describe the standards development process. In this article, we provide an overview of OSAC and the OSAC Forensic Nursing Subcommittee. We discuss how forensic nurses can be involved in the development and advancement of standards that define minimum requirements, best practices, and evidence-based protocols to ensure reliable and reproducible outcomes.

Implications for Forensic Nurses
The development of forensic nursing standards is an important step in advancing the profession. It is critical that forensic nurses are actively involved in the standards development process, which includes volunteering to serve on the OSAC Forensic Nursing Subcommittee or a forensic nursing standards development organization, providing input into standards drafts during the public comment period, and implementing approved standards into practice.
The role of peer support and patient navigation for empowerment in breast cancer survivors: implications for community cancer control
Authors: Sleiman Marcelo M. , Yockel Mary Rose , Fleischmann Adina , Silber Elana , Liu Mingqian , Young Olivia , Arumani Sahana , Tercyak Kenneth P. 
Published: April 2024

Abstract

Background:
Community-based organizations (CBO) offer support, including patient navigation (PN), to women at-risk for (eg, those with BRCA pathogenic variants) and surviving with breast cancer. However, the impacts of CBO efforts on survivors' empowerment (eg, control, self-confidence, knowledge/skills, coping) are largely unknown.

Methods:
As part of a quality improvement initiative (N = 2,247) focused on PN, care satisfaction, peer support, and quality of life (QoL), we conducted a secondary analysis of a CBO care delivery model on women's empowerment.

Results:
Under CBO led cancer control, empowerment was high: most survivors felt confident in (71.2%) and knowledgeable about (66.4%) managing their care. Perceived care quality was also high (91%): it was recommendable to others (93.9%), helpful (92.7%), informative (92.6%), timely (92.2%), reliable (91.5%), supportive (91.3%), and effective (88.7%). Regarding CBO care satisfaction, survivors felt supported by abundant resources (92.8%) and programs (91.2%), understood (92.0%), and helped (91.6%). Peer support (offered to >25%) demonstrated high engagement (>85%). Regarding QoL, 25.3% were in fair/poor health and 25.6% endorsed frequent mental distress (M = 7.2 physically unhealthy days, M = 7.8 mentally unhealthy days, and M = 6.4 activity-limited days within the past month). Disparities in empowerment were observed as a function of survivors' QoL: lowest among those with more frequent mental distress (t = −2.13, P < .05), mentally unhealthy days (r = −0.083, P < .05), and activity-limited days (r = −0.058, P < .05)). These burdens may have influenced survivors' feelings of empowerment, especially among those without peer support (t = 3.77, P < .001), who downgraded the quality of PN (t = 0.60, P < .01), and were least satisfied with CBO cancer control (t = 0.57, P < .01). In a multivariable model adjusting for mental distress, both perceived PN quality (B = 0.16, SE = 0.01, P < .001) and peer support (B = 0.24, SE = 0.13, P = .05) were positively associated with empowerment: survivors who rated their PN higher, and offered peer support, felt more empowered.

Conclusions:
CBO cancer control can uplift most survivors: addressing socially determined disparities, through programs such as peer support, may enhance their effectiveness and particularly among those with poor mental health.
Tracking Fat Grafts by Magnetic Resonance Imaging: A Comparative Study of Adolescent and Adult Patients with Stable Localized Scleroderma
Authors: Ma Xuda , Wang Liquan , Li Tianhao , Li Ziming , Chen Yu , Wang Tianjiao , Long Xiao , Huang Jiuzuo , Wang Xiaojun 
Published: April 2024

Background:
The optimal timing of reconstruction for patients with facial localized scleroderma is uncertain. The purpose of this study was to compare the outcomes of autologous fat transplantation in adolescent and adult patients with stable localized scleroderma.

Methods:
Adolescent (age 10 to 19 years) and adult (age >19 years) patients with no previous surgery were enrolled (n = 10, each group). Preoperative magnetic resonance imaging, blood tests, and dermatological assessments were used to assess disease activity. All patients underwent autologous fat transplantation for anatomic facial fat restoration with preoperative magnetic resonance imaging planning. Preoperative, immediate, and 1-year postoperative 3-dimensional Dixon magnetic resonance imaging scans, with image registration and fusion techniques, were used to track fat grafts. Patient satisfaction was assessed with a 5-point Likert scale.

Results:
There was no significant difference in sex, body mass index, disease severity, or volume of injected fat between the 2 groups (P > 0.05), except for age (P < 0.05). The 1-year postoperative fat graft retention rate was not significantly different, with 36.6% ± 2.4% (range, 25.3% to 49.3%) in the adolescent group and 32.9% ± 1.7% (range, 27.3% to 40.1%) in the adult group (P > 0.05). Surgical outcomes were favorable in all patients, with satisfaction scores of 3.8 ± 0.2 points in the adolescent group and 3.6 ± 0.2 points in the adult group (P > 0.05).

Conclusion:
In patients with stable localized scleroderma, the initial autologous fat transplantation was equally effective in improving facial contour deformity, with no significant difference in fat graft retention or patient satisfaction.
Effect of the ischial support on muscle force estimation during transfemoral walking
Authors: Fougeron Nolwenn , Bonnet Xavier , Panhelleux Brieuc , Rose Jean-Loïc , Rohan Pierre-Yves , Pillet Hélène 
Published: April 2024

Background:
Transmission of loads between the prosthetic socket and the residual limb is critical for the comfort and walking ability of people with transfemoral amputation. This transmission is mainly determined by the socket tightening, muscle forces, and socket ischial support. However, numerical investigations of the amputated gait, using modeling approaches such as MusculoSkeletal (MSK) modeling, ignore the weight-bearing role of the ischial support. This simplification may lead to errors in the muscle force estimation.

Objective:
This study aims to propose a MSK model of the amputated gait that accounts for the interaction between the body and the ischial support for the estimation of the muscle forces of 13 subjects with unilateral transfemoral amputation.

Methods:
Contrary to previous studies on the amputated gait which ignored the interaction with the ischial support, here, the contact on the ischial support was included in the external loads acting on the pelvis in a MSK model of the amputated gait.

Results:
Including the ischial support induced an increase in the activity of the main abductor muscles, while adductor muscles' activity was reduced. These results suggest that neglecting the interaction with the ischial support leads to erroneous muscle force distribution considering the gait of people with transfemoral amputation. Although subjects with various bone geometries, particularly femur lengths, were included in the study, similar results were obtained for all subjects.

Conclusions:
Eventually, the estimation of muscle forces from MSK models could be used in combination with finite element models to provide quantitative data for the design of prosthetic sockets.