bluuebunny/crossref_metadata_2025_split huggingface dataset:
Smooth muscle tumors of the small bowel: A case report and review of the literature
Authors: Sagi A. , Feuchtwanger M. M. , Yanai‐Inbar I. , Walfisch S. 
Published: February 2007

AbstractWe report a rare case of peritonitis caused by perforation of smooth muscle tumor of the jejunum. In spite of having all the reported presenting symptoms of these tumors, the diagnosis was not made preoperatively. Although histopathologically diagnosis was that of a benign tumor, the subsequent course was rapid and malignant. A complete review of the literature is presented.
Univariate and multivariate analyses of 5‐year survival, recurrence, and inguinal node metastases in stage I and II vulvar carcinoma
Authors: Malfetano John H. , Piver M. Steven , Tsukada Yoshiaki , Reese Peter 
Published: February 2007

AbstractNinety‐seven patients with FIGO stage I and II vulvar carcinoma were analyzed for 5‐year survival, inguinal node metastases (N=61), and recurrence. Factors analyzed included stage, tumor grade, depth of invasion, presence or absence of tumor cell confluence, presence or absence of lymphatic/vascular space invasion, lesion size, and lymph node metastases. It was concluded that conservative surgery in patients otherwise suitable for surgery should consist of a wide, local excision of the vulvar lesion in conjunction with ipsilateral inguinal node resection if the tumor measured ⩽ 1 cm in diameter and had a depth of invasion of ⩽ 1 mm. All other stage I or II patients require radical vulvectomy and bilateral inguinal lymphadenectomy.
Historical note on bone and soft tissue sarcoma
Authors: Peltier Leonard F. 
Published: February 2007

AbstractSince antiquity, the large bony and fleshy tumors have been called sarcomas. It was not until after the development of cellular pathology during the middle of the 19th century that sarcomas were separated from carcinomas on the basis of their tissues of origin. This paper traces the growth of these ideas as well as the introduction of effective methods of treatment of the sarcomas.
Pelvic exenteration
Authors: Lindsey William F. , Wood Donald K. , Briele Henry A. , Greager John A. , Walker Michael J. , Bork Jeffrey , Gupta Tapas K. Das 
Published: February 2007

AbstractSixty‐eight patients at the University of Illinois, Cook County, and the West Side Veterans Administration hospitals underwent pelvic exenteration for advanced pelvic malignancies during the 15‐year period from 1969 to 1984. Thirty‐two had colorectal cancers, eleven cervical, seven bladder, and six vulvar; in twelve the cancers were in miscellaneous pelvic sites. Forty‐five exenterations were done with intent to cure, and twenty‐three for palliation of patients with bulky, necrotic tumors that had caused symptomatic fistulae, local sepsis, chronic bleeding, or severe localized pain. The total 30‐day postoperative mortality was 4.4% (3/68). The 5‐year survival rate of patients who underwent curative exenteration was 33% (median 27 months). Pelvic exenteration appears to be a feasible surgical procedure for a variety of advanced malignancies as well as for palliation of severely symptomatic patients.
The surgeon and chemotherapy: Twenty five years personal experience
Authors: Burn Ian 
Published: February 2007

AbstractThe realm of cancer chemotherapy is complex and often conflicting. The massive use of cytotoxic agents during the past 25 years has now reached a point where major decisions have to be made. The respective roles of regional techniques, systemic therapy for metastatic disease and adjuvant cytotoxic chemotherapy, all need the most careful re‐appraisal. It is important that surgical opinion continues to be expressed and that surgeons continue to participate in the study and practice of cancer chemotherapy.
The treatment of primary tumors of the femur with chemotherapy (if indicated), resection and reconstruction with an endoprosthesis
Authors: Veth R. P. H. , Nielsen H. K. L. , Oldhoff J. , Koops H. Schraffordt , Postma A. , Kamps W. , Den Heeten G. J. , Hartel R. M. , Van Krieken F. , Göeken L. N. H. , Oosterhuis J. W. 
Published: February 2007

AbstractThe treatment protocol of 15 patients with a primary tumor of the femur, including osteosarcoma, malignant fibrous histiocytoma and chondrosar‐coma is presented. All patients had been selected for resection and reconstruction with an endoprosthesis. An endoprothesis was implanted in 12 patients.The results of this type of treatment appear to be satisfactory. In eight osteosarcoma cases resection and reconstruction with an endoprosthesis combined with preoperative and postoperative chemotherapy, according to Rosen, were performed. Follow‐up in all 15 patients, varying from 1.4 to 6.0 years, showed no evidence of disease in 12 patients. Three patients had died. Function of the involved leg was satisfactory in most cases.The advantage and disadvantages of the use of an endoprosthesis are discussed as well as complications in this series of patients.
Giant cavernous hepatic hemangioma: Treatment by ligation of the hepatic artery
Authors: Peveretos P. , Panoussopoulos D. 
Published: February 2007

AbstractWe present a case of a giant hepatic hemangioma. We found it at laparotomy and we decided on the course of treatment on the operating table. As right lobectomy was not feasible, we performed ligation of the hepatic artery. The patient made an uneventful recovery. A selective hepatic angiography and a liver scan were performed 8 months postoperatively and they both showed regression of the tumor. The tumor was not demonstrable in the right hepatic artery. The patient is in excellent health 2 years after the operation; the liver is smaller in palpation and the tumor itself is nonpalpable. In this case the ligation of the hepatic artery was a successful therapeutic procedure.
Nonfunctioning parathyroid carcinoma: A case history
Authors: Collins F. David , Warren M. Charles , Palmer Fred J. , Rankin Donald R. 
Published: February 2007

AbstractParathyroid carcinoma is an uncommon endocrine tumor. Its usual clinical presentation is that of primary hyperparathyroidism with elevated serum calcium and parathormone levels. Nonfunctioning carcinoma of the parathyroid gland with normal serum calcium levels is very rare. There are 12 reported cases in the literature. This paper is a case report of a nonfunctioning parathyroid carcinoma and a review of the literature.
Metastases to the cavernous sinus from primary carcinoma of the larynx
Authors: Zahra Mohammed , Tewfik Hamed H. , McCabe Brian F. 
Published: February 2007

AbstractDistant metastases from late stages of carcinoma of the vocal cords can occur. Such metastatic deposit can occur in unusual sites. In this report, we are presenting a patient with spread to the cavernous sinus. Radiation therapy was of palliative value.
A matrix for controlled clinical trials for the study of hepatic metastases: Proceedings of a workshop
Authors: Sugarbaker Paul H. , Van De Velde Cornelius J. H. , Veenhof C. H. N. 
Published: February 2007

AbstractA summary of a workshop held to synthesize the essential elements constituting protocols for the study of new treatments for patients with hepatic metastases is reported. An attempt was made to formulate a consensus on issues of importance in future collaborative research. A staging system was proposed that was thought to be usable by clinicians. The eligibility requirements for surgical resection of hepatic metastases and for the nonsurgical treatment of hepatic metastases is discussed. Criteria for the response to treatment were formulated. The selection of appropriate control groups for new treatment strategies was discussed.
Prognostic factors of esophageal carcinoma: Univariate and multivariate analyses
Authors: Sugimachi Keizo , Matsuura Hiroshi , Kai Hidenobu , Kanematsu Takashi , Inokuchi Kiyoshi , Jingu Kenichi 
Published: February 2007

AbstractThe correlation of 5‐year survival rate with various clinical and histopath‐ological factors was studied using univariate and multiple analyses of 128 patients who had undergone resection for esophageal carcinoma between 1965 and 1978 in the Department of Surgery, Kyushu University Hospital. The depth of penetration, lymph node metastasis, lymphatic or vascular invasion, and INF had a significant correlation with 5‐year survival in the univariate analysis; however, only depth of penetration and lymph node metastasis were prognostic factors with a significant difference, in the multivariate analysis.In 55 patients in whom the cell nuclear DNA content had been determined, the DNA pattern was the greatest prognostic factor (p < 0.01), in multivariate analyses.We propose that the DNA distribution in the malignant cells should be examined as a most pertinent prognostic factor.
Cell surface antigens in squamous cell carcinoma of the oral cavity
Authors: Das S. N. , Khanna N. N. , Khanna Sushila , Gupta S. 
Published: February 2007

AbstractThe ABH isoantigen was investigated in 80 patients with squamous cell carcinoma of the oral cavity and in‐their 46 affected lymph nodes. Isoantigen deletion shows a characteristic pattern of benign to malignant transformation of oral cancer. Total loss of isoantigen was found in anaplastic tumours, in metastatic lymph nodes and in the majority of advanced stage tumours. Total loss of isoantigen in metastatic lymph nodes indicates a frequent discharge of isoantigen‐negative metastatic cells from the primary tumours to the lymph nodes and the regional organs. It seems that with the recent techniques a prospective observation of ABH isoantigen added to other pathological and clinical findings could be of prognostic significance in patients with squamous cell carcinoma of the oral cavity.
Cholesonographic characteristics of cystic duct metastasis causing acute acalculous cholecystitis: Case report
Authors: Andry G. , Turnbull A. D. , Botet J. , Kurtz R. C. 
Published: February 2007

AbstractA variety of epithelial malignancies are capable of metastasizing to the bile ducts and gall bladder in a fashion distinct from concurrent spread to the liver. Ultrasonography has proved useful in evaluating obstructive jaundice in this setting and, in the case described, accurately diagnosed acute acalculous cholecystitis caused by a solitary metastasis from carcinoma of the breast to the cystic duct. Exploratory laparotomy confirmed the accuracy of this preoperative diagnosis.
Breast cancer and meningioma
Authors: Miller Robert E. 
Published: February 2007

AbstractA unique association between meningioma and breast cancer has recently been observed. A review of the literature reveals 33 such cases. Certain similarities exist between these two tumors. They each occur more frequently in women in the fifth and sixth decade, and pregnancy accelerates the symptoms of both entities. Furthermore, an increase in estrogen and progesterone receptor protein has been noted in each. A patient with established breast cancer who presents with central nervous system symptoms cannot be assumed to have cerebral metastases. A thorough workup to rule out meningioma is necessary. Furthermore, patients with proven meningioma must be observed closely for the subsequent development of breast cancer.
Efficacy of polyglycolic acid mesh sling in keeping the small bowel in the upper abdomen after abdominal surgery: A 12‐month study in baboons
Authors: Devereux Dennis F. , Feldman Merrill I. , McIntosh Tracy K. , Palter Marc D. , Kavanah Maureen T. , Deckers Peter J. , Williams Lester F. 
Published: February 2007

AbstractThe purpose of this study was to determine if a “sling” made of polyglycolic acid (PGA) would be a reliable method of preventing small bowel descent into the pelvis following abdominal surgery. Baboons were used, as they respond to infection and ambulate similarly to humans. Animals had the small bowel mobilized to the upper abdomen and had the PGA “sling” sewn into place. Documentation of small bowel position was evaluated by upper gastrointestinal series over the 12‐month study. Small bowel descent into the pelvis was prevented by utilization of the PGA “sling.” Animals were sacrificed and autopsied, and sections of small bowel were taken. There was no evidence of mesh, obstruction, sepsis, fistulae, or herniation in animals at autopsy. Small bowel sections were considered normal histologically.Utilization of PGA sling appears to be a safe and reliable method of preventing small bowel descent into the pelvis after abdominal surgery.
Pneumocystography as an aid in the diagnosis of cystic lesions of the breast
Authors: Sanders Thomas J. , Morris Don M. , Cederbom Gunnar , Gonzalez Enrique 
Published: February 2007

AbstractPneumocystography is used in Europe in managing breast cysts. This involves aspiration, air insufflation, and completion mammography. Pneumocystography allows accurate delineation of the cyst wall and contents. Pneumocystograms that do not demonstrate intracystic lesions negate the need for cyst excision in many cases. Microcalcifications may become visible after pneumocystography. Intracystic masses, positive cyst fluid cytology, bloody cyst fluid, cyst recurrence, or evidence of an extrinsic mass compressing the cyst are all indications for operation. Intracystic cancers can and do metastasize. Pneumocystography may be beneficial in detecting these cancers.
The effect of tumor size and axillary lymph node metastasis on estrogen and progesterone receptors in primary breast cancer
Authors: Alghanem A. A. , Hussain S. 
Published: February 2007

AbstractWe evaluated the estrogen receptors (Er) and the progesterone receptors (Pr) in 209 female patients with primary breast cancer. There is statistically a very highly significant negative correlation between the size of the tumor and the Pr (p = 0.007); large tumor contains low Pr. The same correlation was found with Er, but it was not statistically significant (p = 0.40). There is also a negative correlation between the number of axillary metastatic lymph nodes and Er and Pr, but this was not statistically significant.
Metastatic breast carcinoma of the gallbladder
Authors: Beaver Bonnie L. , Denning David A. , Minton John P. 
Published: February 2007

AbstractMetastasis of breast carcinoma to the gallbladder, not hitherto reported, occurred in a 73–year‐old woman who had acute cholecystitis. After cholecystectomy was performed, pathologic examination of the specimen demonstrated tumor morphologically identical to the breast carcinoma for which the patient had undergone right mastectomy 3 years earlier.
Superficial spreading esophageal cancer controlled by hyperthermo‐chemo‐radiotherapy: A case report
Authors: Matsufuji Hidemasa , Ikejiri Koji , Kai Hidenobu , Sugimachi Keizo , Inokuchi Kiyoshi 
Published: February 2007

AbstractHyperthermo‐chemo‐radiotherapy (HCR) was prescribed for a patient with superficially spreading esophageal cancer, since severe lung dysfunction presented too great a surgical risk. Viable cancer cells completely disappeared after HCR and 8 months later, at this writing, the patient is living in good condition. Conservative treatment with HCR for patients with esophageal cancer is effective for carefully selected patients.
Determinants of survival after intraarterial infusion of 5‐fluorouracil for liver metastases from colorectal cancer: A multivariate analysis
Authors: Ekberg Henrik , Tranberg Karl‐Göran , Lundstedt Christer , Hanff Gunnar , Ranstam Jonas , Jeppsson Bengt , Bengmark Stig 
Published: February 2007

AbstractA consecutive series of 73 patients treated with intraarterial infusion of 5‐fluorouracil (5‐FU) for liver metastases from colorectal primary was studied retrospectively using multivariate analysis in order to find determinants of survival. Nontreatment factors had a great impact on variation in survival with liver tumor volume and metastases to lymph glands in the liver hilum as major prognostic determinants. In addition, survival from onset of treatment varied with the interval between the primary operation and the diagnosis of liver metastases. Treatment with intraarterial 5‐FU was more effective when administered at long‐term (3 months every 6 months) than at short‐term (5 days every 6 weeks). Single temporary dearterialization, used as an adjunct to infusion of 5‐FU, had a negative impact on length of survival and was followed by a high frequency of complications. The occurrence of hepatic arterial thrombosis was associated with comparatively good prognosis.
Histiocytoid carcinoma: A variant of breast cancer
Authors: Eisenberg Burton L. , Bacnall James W. , Harding Clarke T. 
Published: February 2007

AbstractThe history of a patient presenting with metachronous bilateral breast cancer displaying histiocytoid features is reviewed. Although regional metastases were noted, this patient has not demonstrated an aggressive systemic disease pattern. In the past, histiocytoid breast cancer has been classified as either a lipid‐rich carcinoma or as a variant of lobular carcinoma. However, histiocytoid carcinoma should be considered a distinct entity. Unlike the lipid‐rich carcinomas, this tumor stained strongly for mucin. Immunoperoxidase staining indicated strong positivity for CEA and negative staining for alpha‐lactabumin. There is suggestive evidence of a relationship between histiocytoid breast carcinoma and breast cancers of apocrine origin. Controversy remains and further evaluation is needed to elucidate the histiogenesis and biological potential of this neoplasm.
Metastatic colonic carcinoma to the testes: Case report and review of the literature
Authors: Jubelirer Steven J. 
Published: February 2007

AbstractA case of metastatic carcinoma to the testes from the colon is reported and 14 previous case reports reviewed. The range in age of reported patients was 18 to 76, with a median age of 51 years. The clinical presentation in most cases was testicular swelling or hydrocoele. in three cases, The testicular lesion antedated the discovery of a primary colorectal cancer. The majority of patients had other widespread metastases at the time testicular involvement was diagnosed. in older patients who present with a testicular mass or hydrocoele, The differential diagnosis must include metastatic carcinoma.
Malignant retroperitoneal paragangliomas
Authors: Mikhail Raouf A. , Moore James B. , Reed Donald N. , Abbott Roderic R. 
Published: February 2007

AbstractThe authors reviewed the clinical features of 13 cases of malignant retroperitoneal paragangliomas reported in the English literature and report the 14th case. The reported case represents the first such tumor occurring in the familial form of the disease. Good response to combination chemotherapy in the reported case emphasizes the need to study the role of chemotherapy in the management of this neoplasm.
Etoposide (VP‐16) plus cisplatin (DDP): A new active chemotherapeutic combination in patients with stage iii‐iv ovarian adenocarcinoma
Authors: Barlow Joseph J. , Lele Shashikant B. 
Published: February 2007

AbstractTen patients with Stage III‐IV ovarian adenocarcinoma were treated with the drug combination etoposide (VP‐16) plus cisplatin (DDP). All patients were in relapse following prior vigorous, uninterrupted treatment with three or more lines of chemotherapy that included (1) courses of weekly 1‐mg/kg single‐agent DDP, (2) DDP 50 mg/m2 in various combinations with or without cytoxan, adriamycin and hexamethylmelamine q 4 weeks and (3) highdose methotrexate‐leucovorin plus cyclophosphamide (MECY) q 4 weeks. The median duration of treatment prior to starting VP‐16‐DDP was 27.5 months (range 6 to 53 months). VP‐16‐DDP was given as a 2‐day regimen repeated every 4 weeks. VP‐16, 100‐150 mg/m2, was given on days 1 and 2, and 50 mg/m2 of DDP on day 1 only. The finding of 50 % partial response and 38 % stabilization of measurable tumor was remarkable in patients so extensively pretreated. The responses were not due to increased DDP dosage, but rather to an apparent synergism between VP‐16 and DDP.
Cystic islet cell tumor of the pancreas
Authors: Michael Stair J. , Schaefer Robert F. , McCowan Timothy C. , Balachandran S. 
Published: February 2007

AbstractPresented is the fifth case of a cystic islet cell tumor of the pancreas. The diagnosis is usually made postoperatively but should be considered in a patient with “recurrent pseudocyst” or a history incompatible with pseudocyst in combination with a cystic area in the pancreas. Computed tomography is preferred for diagnosis, and resection is the preferred therapy.
Adjuvant chemotherapy in Ewing's sarcoma
Authors: Advani S. H. , Rao D. N. , Dinshaw K. A. , Nair C. N. , Gopal R. , Vyas J. J. , Desai P. B. 
Published: February 2007

AbstractAdjuvant chemotherapy using vincristine, cyclophosphamide, and adriamycin was used in 28 patients with localized Ewing's sarcoma. Life‐table analysis revealed 55% disease‐free survival at 3 years. in contrast, our historical control showed less than 10% long‐term survival. Adjuvant chemotherapy appears to control both micrometastasis as well as local residual disease. The present study demonstrates the improved survival with adjuvant chemotherapy including adriamycin, vincristine, and cyclophosphamide, in patients with localized Ewing's sarcoma.
Leiomyosarcoma of the anus treated with sphincter‐preserving surgery and radiation therapy
Authors: Minsky Bruce D. , Rich Tyvin A. , Mies Carolyn 
Published: February 2007

AbstractThe sixth published case of a leiomyosarcoma of the anus is reported and the previous literature reviewed. Treatment with successful preservation of anal sphincter function is described. Local excision of the tumor was followed by external beam radiation therapy and an Iridium‐192 implant. The details and rationale for this mode of therapy for resectable anal tumors are discussed.
Ewing's sarcoma metastatic to focal nodular hyperplasia of liver
Authors: Hagay Z. J. , Zirkin Howard J. , Moses Martha , Khodadadi Jalinus 
Published: February 2007

AbstractA case is presented of a young woman discovered at thoracotomy to have Ewing's sarcoma of the left lower ribs with soft tissue extension to the diaphragm and thoracic wall. Laparotomy at the same operation showed a nodule of focal nodular hyperplasia of the liver with a focus of metastasis from the sarcoma within the area of hyperplasia. This is the first report of metastasis of any tumor to a hepatic lesion of this sort. Possible reasons for metastasis to this type of lesion are discussed.
Dysplastic nevus syndrome: Association with multiple primary neoplasms
Authors: Dabski Krzysztof , Milgrom Halina , Stoll Howard L. 
Published: February 2007

AbstractA 65‐year‐old white man with dysplastic nevus syndrome is presented. The patient also developed an extramammary Paget's disease of the scrotum, two malignant melanomas of the skin of the arm and abdomen, two squamous cell carcinomas in the mouth, and several benign tumors such as lentigo maligna, dermatofibroma, and a cavernous hemangioma. Besides the well‐established tendency of patients with the dysplastic nevus syndrome to develop malignant melanomas of the skin, The ir possible propensity to develop other primary malignant neoplasms is discussed.