bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Validity of Heart Rate Variability (HRV) in Educational Research and a Synthesis of Recommendations
Authors: Kim Hyun Jin , Park Yuyi , Lee Jihyun 
Published: April 2024

AbstractThis study provides a comprehensive overview of methodological aspects when using heart rate variability (HRV) measures in educational research. Following PRISMA 2020 guidelines, we searched four databases for relevant studies published until March 5, 2024. From the 48 studies reviewed, we extracted data across three analytical categories: (1) area of study interest and participant populations, (2) data collection and analysis methodologies, and (3) the concurrent and predictive validity of HRV measurement for educational research. Study quality was evaluated using QualSyst assessment criteria. Most studies measured stress and enlisted undergraduate students as participants. Data were predominately collected using wearable devices, measuring HRV for durations of less than 30 min, and in varied contexts, including during exams, while learning, and in experiments. The parameters analyzed varied within both time and frequency domains. HRV data had a moderate level of concurrent validity as a measure of stress in an educational context. The concurrent validity of HRV data for measuring attention remains uncertain with insufficient evidence. Limited correlations appeared between stress and performance. The findings, potentials, and limitations of HRV measures are discussed, and synthesized recommendations for educational research using HRV data are provided.
A holistic approach for tourism carrying capacity estimation in sensitive ecological areas
Authors: Skiniti Georgia , Lilli Maria , Skarakis Nikolaos , Tournaki Stavroula , Nikolaidis Nikolaos , Tsoutsos Theocharis 
Published: April 2024

AbstractMediterranean ecosystems are in the spotlight of tourism activities, with the local populations trying to make the most of them, while in parallel, the stress signs, such as habitat and biodiversity degradation, increased pollution, or beach erosion, have begun to emerge. Furthermore, this combination of exotic and delicate qualities accompanied by excessive tourist flows leads to the imperative need for sustainable tourism development studies in these areas. In the current study, aiming to develop a new holistic framework for assessing Carrying Capacity in sensitive coastal ecosystems, a combined methodology was created and tested in Balos Lagoon, a Natura 2000 area in Western Crete. The method encompasses calculating different Carrying Capacity indicators, environmental quality measurements, visitors’ perceptions identification, and finally, a multicriteria analysis to capture the stakeholders’ and local community’s viewpoints. The combined methodologies identified vital issues, including overcrowding—Effective Carrying Capacity is exceeded by 1000 people per day during the peak season—tar residue pollution, microplastics, insufficient road infrastructure and excessive car numbers exceeding capacity. Stakeholder involvement was pivotal, prioritizing twelve proposed actions to address those issues. Notably, “frequent beach clean-ups,” targeting visual impacts, emerged as the most critical action, while parking reallocation and setting a maximum daily ferry limit were also highly ranked, promising solutions to alleviate overcrowding issues. The paper offers valuable insights for future research, emphasizing the need for continuous environmental monitoring, implementation of high-priority measures, and economic valuation of natural capital. Ultimately, this research contributes to the literature by presenting a pioneering methodology for holistic assessment and sustainable tourism development in Mediterranean sensitive coastal ecosystems.
Electronic shopping cart abandonment: What do we know and where should we be heading?
Authors: Chopra Ishani Patharia , Jebarajakirthy Charles , Jain Tanu , Maseeh Haroon Iqbal 
Published: April 2024

Abstract This paper aims to systematically review the literature on electronic shopping cart abandonment (ESCA). It analyzes the development of ESCA literature in terms of publication trends, publication outlets, number of citations, methodologies, and theoretical underpinnings. Furthermore, based on the literature synthesis, this review proposes a conceptual framework integrating the widely used antecedents, mediators, and moderators that influence ESCA. The antecedents include customer attributes and website-related factors while research and comparison mediate the relationship between these antecedents and ESCA. Using lexicometric analysis, this SLR identified key themes studied in ESCA literature over time, including customer decision-making criteria, motives and characteristics, online shopping environment, and website attributes. Further, this SLR suggests future research directions to advance ESCA literature from theoretical, contextual, and methodological perspectives. This SLR also suggests strategies for e-retailers and marketers to overcome ESCA. Overall, this review is a silver line in ESCA literature.
Advances in tumor microenvironment and underlying molecular mechanisms of bladder cancer: a systematic review
Authors: Tang Liu , Xu Haifei , Wu Tong , Wu Wenhao , Lu Yuhao , Gu Jijia , Wang Xiaoling , Zhou Mei , Chen Qiuyang , Sun Xuan , Cai Hongzhou 
Published: April 2024

AbstractBladder cancer is one of the most frequent malignant tumors of the urinary system. The prevalence of bladder cancer among men and women is roughly 5:2, and both its incidence and death have been rising steadily over the past few years. At the moment, metastasis and recurrence of advanced bladder cancer—which are believed to be connected to the malfunction of multigene and multilevel cell signaling network—remain the leading causes of bladder cancer-related death. The therapeutic treatment of bladder cancer will be greatly aided by the elucidation of these mechanisms. New concepts for the treatment of bladder cancer have been made possible by the advancement of research technologies and a number of new treatment options, including immunotherapy and targeted therapy. In this paper, we will extensively review the development of the tumor microenvironment and the possible molecular mechanisms of bladder cancer.
DSCAM-AS1 promotes the development of prostate cancer
Authors: Cheng Lin , Li Shuhui , Jiang Deqi , Zhang Jianchao 
Published: April 2024

Abstract
Purpose
The purpose of this study was to investigate the role of lncRNA DSCAM-AS1 in prostate cancer to find new therapeutic targets and promote the research progress of prostate cancer.

Methods
RT-qPCR was used to detect DSCAM-AS1 expression in prostate cancer tissues, normal tissues, human normal prostate epithelial cells (RWPE), and four prostate cancer cell lines. The clinical and prognostic role of DSCAM-AS1 was evaluated by the Kaplan–Meier curve and chi-square test. Secondly, a dual luciferase reporter gene assay was used to study the regulatory mechanism between miR-338-3p and DSCAM-AS1. Finally, the roles of DSCAM-AS1 and miR-338-3p in prostate cancer cell proliferation and metastasis were explored by CCK-8 and Transwell assays.

Results
It was found that DSCAM-AS1 upregulation could serve as a warning of deterioration and poor prognosis in prostate cancer patients, and that knockdown of DSCAM-AS1 expression inhibited the progression of prostate cancer cells. In addition, miR-338-3p, a target of DSCAM-AS1, was found to be down-regulated in prostate cancer cells and miR-338-3p knockdown could reverse the inhibitory effect of DSCAM-AS1 silencing on prostate cancer.

Conclusion
DSCAM-AS1 is up-regulated in prostate cancer and regulates the progression of prostate cancer cells by targeting miR-338-3p.
Serum klotho levels and mortality patterns in frail individuals: unraveling the u-shaped association
Authors: Luo Huanhuan , Zheng Zitian , Hu Huixiu , Sun Chao 
Published: April 2024

Abstract
Background
Frailty, a clinical syndrome intricately linked with the aging process, stands as a harbinger of numerous adverse outcomes, most notably mortality. This study aimed to elucidate the association between serum α-klotho concentration and mortality patterns, including all-cause and cause-specific mortality, in patients with frailty.

Methods
The study employed Cox proportional hazard models, smoothed curve fitting, and supplementary analyses, encompassing threshold effect analysis, subgroup and sensitivity analyses, to explore the relationship between α-klotho levels and mortality, including all-cause, CVD, and cancer-related mortality.

Results
Among the 2,608 frail individuals (mean age: 60.78 [SD 10.48] years; 59.89% female), the mortality stood at 25.35% during a median follow-up period of 6.95 years. Both unadjusted and adjusted models revealed a significant inverse association between higher serum α-klotho levels and the risk of all-cause and CVD-related mortality ([mean(95% CI) 0.68 (0.55, 0.83)] for all-cause mortality; [mean(95% CI) 0.48 (0.32, 0.74)] for CVD-related mortality, all P for trend < 0.001). Notably, log2–klotho displayed a U-shaped correlation with all-cause mortality and cancer mortality, characterized by thresholds of 9.48 and 9.55, respectively. The robustness of these findings was consistently supported by subgroup and sensitivity analyses.

Conclusion
This study unveils a U shaped association between serum α-klotho levels and both all-cause and cancer-related mortality among middle-aged and elderly individuals with frailty in the United States. The identified serum α-klotho thresholds, at 714.8 pg/ml for all-cause mortality and 750.6 pg/ml for cancer-related mortality, hold promise as potential targets for interventions aimed at mitigating the risks of premature death and cancer within this vulnerable population.
Analysis of fractional differential equation to compare the dynamic behavior of a single degree of freedom system models using a shaking table
Authors: Márquez Erick , Romo Miguel , Hermosillo Armando , Brambila Fernando , Magaña Roberto 
Published: April 2024

AbstractA mathematical model to describe the dynamic behavior of a single degree of freedom system, SDFS, model in springs and damps assembles in series and parallel models in a laboratory, is presented. Kelvin–Voigt fractional derivative rheological models, KVFRdm, was used to solve the fractional differential equations of motion by numerical methods.
Cross diffusion effects on MHD double diffusive viscous flow through Hermite wavelet method
Authors: Nagappanavar Suma Nagendrappa , Raghunatha K. R. , Kumar D. L. Kiran 
Published: April 2024

AbstractDouble-diffusive convection is a form of fluid flow that occurs when two processes of molecular diffusion are active in a fluid at the same time, causing instabilities and also complicated behaviour. One chemical or biological species concentration can cause a flux of another species, either linearly or nonlinearly, a phenomenon known as cross-diffusion. The cross-diffusion effects on double-diffusive MHD fluid flow through the Hermite wavelet method is examined. The governing coupled partial differential equations of the problem under consideration are transformed to highly nonlinear ordinary differential equations over a finite domain with the help of similarity transformations. The results are obtained for the skin friction coefficient, as well as the velocity, temperature and the concentration profiles for some values of the governing parameters, namely, the cross diffusion terms, Hartmann number, thermophoresis parameter, squeeze number, Prandtl number and suction/injection parameter. The obtained results are validated against previously published results for special case of the problems.
Flight performance analysis of aerial fire fighting
Authors: Struminska A. , Filippone A. 
Published: April 2024

AbstractThis paper investigates the operational patterns and techniques of aerial fire fighting. It is demonstrated that manoeuvrability and endurance are the main characteristics when choosing air tactical aircraft; focus is on load capability for helicopters and air tankers. Water tank filling and deployment techniques are evaluated. Aircraft using pressure deployment systems are found to produce more uniform and heavy coverage in comparison with gravity systems. ADS-B open source data of flight operations and performance was collected. Operational patterns are found to be independent on the size of particular aircraft category (non-amphibious and amphibious air tanker, helicopter, air-tactical aircraft). Effectiveness and cost are modelled using the retardant dropped per operation and the average number of daily missions. The largest aircraft, Type-I helicopters and very large air tankers (VLAT) are found to be the most effective water- and retardant-dropping aircraft. The best cost-to-litre-dropped ratio for water-dropping aircraft is attributed to Type-III helicopters and amphibious Type-III aircraft; for retardant-dropping aircraft, VLAT are most effective. To maximise fire fighting effectiveness, Type-I helicopters and VLAT should be used as far as possible, with pressure deployment systems.
Machine Learning with High-Cardinality Categorical Features in Actuarial Applications
Authors: Avanzi Benjamin , Taylor Greg , Wang Melantha , Wong Bernard 
Published: April 2024

AbstractHigh-cardinality categorical features are pervasive in actuarial data (e.g., occupation in commercial property insurance). Standard categorical encoding methods like one-hot encoding are inadequate in these settings.In this work, we present a novel Generalised Linear Mixed Model Neural Network (“GLMMNet”) approach to the modelling of high-cardinality categorical features. The GLMMNet integrates a generalised linear mixed model in a deep learning framework, offering the predictive power of neural networks and the transparency of random effects estimates, the latter of which cannot be obtained from the entity embedding models. Further, its flexibility to deal with any distribution in the exponential dispersion (ED) family makes it widely applicable to many actuarial contexts and beyond. In order to facilitate the application of GLMMNet to large datasets, we use variational inference to estimate its parameters—both traditional mean field and versions utilising textual information underlying the high-cardinality categorical features.We illustrate and compare the GLMMNet against existing approaches in a range of simulation experiments as well as in a real-life insurance case study. A notable feature for both our simulation experiment and the real-life case study is a comparatively low signal-to-noise ratio, which is a feature common in actuarial applications. We find that the GLMMNet often outperforms or at least performs comparably with an entity-embedded neural network in these settings, while providing the additional benefit of transparency, which is particularly valuable in practical applications.Importantly, while our model was motivated by actuarial applications, it can have wider applicability. The GLMMNet would suit any applications that involve high-cardinality categorical variables and where the response cannot be sufficiently modelled by a Gaussian distribution, especially where the inherent noisiness of the data is relatively high.
Exploring Volunteer Pharmacists’ Experiences in Responding to 2023 Türkiye Earthquakes: A Qualitative Phenomenological Study
Authors: Uzun Mehmet Barlas , Gülpınar Gizem , Iqbal Ayesha 
Published: April 2024

Abstract

Objective:
Pharmacists are vital in disaster response efforts, dispensing essential medications, managing pharmacy services, consulting, and educating survivors regarding their medications. Their contributions, however, are often underrepresented in scientific literature. This study aimed to explore the experiences of pharmacists who provided pharmacy services to meet the pharmaceutical needs of the survivors after 2 major earthquakes in Türkiye in 2023.

Methods:
This study adopted a phenomenological approach. Data were collected using semi-structured interviews. Purposive sampling was used to invite pharmacists who provided pharmacy services to survivors. Interview transcripts were analyzed following an inductive, reflexive thematic analysis.

Results:
In total, 15 pharmacists were interviewed. Four main overarching themes “response to the earthquake,” “preparedness for the earthquake,” “experiences during service delivery,” and “mental and physical experiences” were developed.

Conclusions:
From participants’ experiences, it is essential to expand the clinical responsibilities of pharmacists and train them in providing wound care, administering immunization, and prescribing. Pharmacists should be integrated as essential members of disaster health teams. International health organizations, nongovernmental organizations, and governments are encouraged to work collaboratively and develop disaster management plans including pharmacists in early responders. This might help mitigate the deficiencies and overcome challenges in health-care systems to provide effective patient-centered care by health professionals and respond effectively to disasters.
Rescuing Hegel from Eurocentrism: Oriental Reconstructions of Hegel's Orient
Authors: Murthy Viren 
Published: April 2024

AbstractHegel's Eurocentrism has become something of an elephant in the room, too obvious to merit discussion. The secondary literature on Hegel often concedes that many of Hegel's comments about the Orient are misguided and uninformed, and then declares that such remarks are of no consequence to his philosophy. However, recently, some scholars have contended that Hegel's view of freedom is fundamentally connected to his negative vision of the Orient and Africa. For example, Alison Stone asserts that Hegel's idea of freedom is premised on his Eurocentrism and colonialism. Drawing on Peter Sahota's essay on Hegel and Hinduism, she argues that Hegel's idea of freedom as liberation from nature tends to exclude non-Western conceptions of freedom. If Stone's contention is true, there would be no way to, as she puts it, save Hegel from himself. I argue that we can move some way towards rescuing Hegel by noting how scholars from modern Asia incorporated some of Hegel's ideas to struggle against Eurocentrism. This essay will read Hegel's comments on the Orient in light of his larger philosophy and then examine how Japanese scholars, specifically Okakura Tenshin (1863–1913) construct what could be called a Hegel-inspired defense of the concept of Asia or the Orient. I claim that if one understands the excesses of Western life to be linked to a vision of freedom based merely on self-interest and pleasure, when scholars and activists from Asia question Western culture, they actually follow Hegel's insights. Okakura, who studied Hegel in college, rethought Asia as overcoming the abstract individualist freedom of the West and replacing it a more holistic, and partially, Hegelian form of freedom.
Behavioral economics enhancers
Authors: Yechiam Eldad 
Published: April 2024

Abstract
Recent meta-analyses suggest that certain drugs act as cognitive enhancers and can increase attentional investment and performance even for healthy adults. The current review examines the potential of behavioral economics enhancers (BEEs) for similarly improving cognitive performance and judgments. Traditionally, behavioral economics theory has adopted a skeptical approach regarding the notion of whether individuals can overcome judgment biases through variables that increase cognitive effort. We focus mostly on the effects of two BEEs: incentivization and losses. Summarizing results from different meta-analyses, we find a small but robust positive effect size for BEEs, with comparable effect sizes to those found in studies of pharmacological cognitive enhancers.
A Postcolonial Legal Critique of Online Expression in Africa
Authors: Ilori Tomiwa 
Published: April 2024

AbstractFar beyond the contributions of African and western thought on the right to freedom of expression, there are now normative developments under international human rights law on how states can protect online expression. However, these developments are not applied in African countries. A reason for this is the extant provisions in various laws that threaten online expression. This article applies postcolonial legal theory to understand why and how these provisions threaten online expression in African countries. It identifies relevant thoughts on the right to freedom of expression, normative developments on the right and a new form of digital colonialism in Africa. It concludes that for African states and other actors to combat this new form of digital colonialism head-on, they must carry out targeted legal reform that repeals and amends these provisions.
Adolescent OCD Patient and Caregiver Perspectives on Identity, Authenticity, and Normalcy in Potential Deep Brain Stimulation Treatment
Authors: Smith Jared N. , Dorfman Natalie , Hurley Meghan , Cenolli Ilona , Kostick-Quenet Kristin , Storch Eric A. , Lázaro-Muñoz Gabriel , Blumenthal-Barby Jennifer 
Published: April 2024

AbstractThe ongoing debate within neuroethics concerning the degree to which neuromodulation such as deep brain stimulation (DBS) changes the personality, identity, and agency (PIA) of patients has paid relatively little attention to the perspectives of prospective patients. Even less attention has been given to pediatric populations. To understand patients’ views about identity changes due to DBS in obsessive-compulsive disorder (OCD), the authors conducted and analyzed semistructured interviews with adolescent patients with OCD and their parents/caregivers. Patients were asked about projected impacts to PIA generally due to DBS. All patient respondents and half of caregivers reported that DBS would impact patient self-identity in significant ways. For example, many patients expressed how DBS could positively impact identity by allowing them to explore their identities free from OCD. Others voiced concerns that DBS-related resolution of OCD might negatively impact patient agency and authenticity. Half of patients expressed that DBS may positively facilitate social access through relieving symptoms, while half indicated that DBS could increase social stigma. These views give insights into how to approach decision-making and informed consent if DBS for OCD becomes available for adolescents. They also offer insights into adolescent experiences of disability identity and “normalcy” in the context of OCD.
Active citizen or pest? Civic authorities, democratization and citizenship in inter-war England
Authors: Ryder Lewis 
Published: April 2024

Abstract
In the 1920s, the art collector John Hilditch tirelessly undertook a public campaign to have his objects exhibited at the Manchester City Art Gallery. This article uses his struggle as a lens through which to examine how the relationship between the civic museum and its citizens was reshaped during the transition to mass democracy. Historians have explored how civic authorities responded to the challenge of mass democratization by encouraging their citizens to become ‘active’, but we know little about how the citizens responded to this call. Hilditch’s campaign allows us to see what public platforms citizens could negotiate to become ‘active’ citizens, and just how far they could influence civic policy.