bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Best Exercise Modality and Dose for Reducing Pain in Adults With Low Back Pain: A Systematic Review With Model-Based Bayesian Network Meta-analysis
Authors: Liang Zhide , Tian Shudong , Wang Chuanzhi , Zhang Meng , Guo Hengzhi , Yu Yingdanni , Wang Xianliang 
Published: March 2024

OBJECTIVE: To quantify the dose-response relationship between overall and specific exercise modalities and pain, in patients with nonspecific chronic low back pain (LBP). DESIGN: Systematic review with Bayesian network meta-analysis. LITERATURE SEARCH: We searched the Medline, Embase, Web of Science, Cochrane Library, Scopus, and SPORTDiscus databases from inception to June 2023. STUDY SELECTION CRITERIA: We included randomized controlled trials of exercise interventions in adults with nonspecific chronic LBP and at least 1 pain outcome reported at the main trial end point. DATA SYNTHESIS: A random-effects network meta-analysis was conducted. We assessed risk of bias using the Cochrane Risk of Bias Tool 2.0, and used the GRADE approach to judge the certainty of evidence for each outcome. RESULTS: Eighty-two trials were included (n = 5033 participants). We found a nonlinear dose-response relationship between total exercise and pain in patients with nonspecific chronic LBP. The maximum significant response was observed at 920 MET minutes (standardized mean difference = −1.74; 95% credible intervals: −2.43, −1.04). The minimal clinically important difference for achieving meaningful pain improvement was 520 MET minutes per week. The dose to achieve minimal clinically important difference varied by type of exercise; Pilates was the most effective. The certainty of the evidence was very low to moderate for all outcomes. CONCLUSION: The dose-response relationship of different exercise modalities to improve pain in patients with nonspecific chronic LBP had a U-shaped trajectory and low- to moderate-certainty evidence. The clinical effect was most pronounced with Pilates exercise. J Orthop Sports Phys Ther 2024;54(5):315-327. Epub 8 March 2024. doi:10.2519/jospt.2024.12153
Surgical management of intramedullary cervical spinal sarcoidosis complicated by transient unilateral weakness: A case report
Authors: Saade Aziz , Denwood Hayley M. , Tannoury Tony , Tannoury Chadi 
Published: March 2024

Background:
Sarcoidosis, a multisystem inflammatory non-caseating granulomatous disease, can present with neurologic lesions in up to 10% of patients.

Case Description:
A 57-year-old male presented with three months of worsening upper extremity radicular pain associated with dysmetria, hyperreflexia, bilateral Hoffman’s, and positive Babinski signs. The contrast magnetic resonance imaging (MRI) showed a diffuse T2 signal hyperintensity and T1-enhancing 2.5 cm lesion extending sagittally between C4 and C6. The cerebrospinal fluid analysis showed a high protein level and lymphocytic pleocytosis. A cardiac positron emission tomography scan was consistent with the diagnosis of cardiac sarcoidosis. With the diagnosis of multisystemic/probable neurosarcoidosis, the patient was unsuccessfully treated with intravenous methylprednisolone, followed by infliximab. Due to severe cord compression/myelopathy, a C3–C6 laminectomy and C3–C7 posterior spinal fusion were performed. Postoperatively, the patient developed a transient right-sided hemiparesis. Over nine postoperative months, the patient had four relapses of transient repeated episodes of paresis, although follow-up cervical MRI scans revealed adequate cord decompression with a stable intramedullary hyperintense lesion.

Conclusion:
Patients with neurosarcoidosis respond unpredictably to surgical decompression and require prolonged medical care, which is often unsuccessful.
Gamma Knife radiosurgery for the management of glomus jugulare tumors: A systematic review and report of the experience of a radioneurosurgery unit in Latin America
Authors: Molina-Romero Oscar I. , Fonnegra-Caballero Andrés , Diez-Palma Juan Carlos , Segura-Hernández Andrés , Rodriguez-Noreña Valentina , Segura-Hernández Gloria , Corredor-Torres Valentina , Rojas-Ortiz María Clara , Useche-Aroca Diana , Fonnegra-Pardo Julio R. 
Published: March 2024

Background:
Glomus jugulare tumors (GJTs) are rare and mainly affect women between the 5th and 6th decades of life. Its localization and anatomic relationships make conventional surgical treatment difficult and with a considerable risk of complications. This manuscript aims to describe the results of Gamma Knife radiosurgery (GKR) in patients with GJT treated in a single center in Latin America, as well as to systematically review the literature to determine the clinical and radiological effectiveness of this technique.

Methods:
A search of information from January 1995 to June 2023 was performed. Twenty-two articles reporting 721 GJT patients treated with GKR were included in the study. Variables such as symptomatic control, control of tumor size, and complications were evaluated. These variables were described using measures of central tendency and proportions. For the institutional experience, 77 patients with GJT tumors were included in the study. Pre-treatment clinical variables and follow-up data were collected from medical charts and phone interviews. The Short Form-36 scale was applied to assess the quality of life. The data were analyzed using the statistical program STATA17.0.

Results:
A total of 721 patients were considered. The median of patients included in these studies was 18.5. The mean age was 58.4 years. The median of symptom control was 89%, and the median of imaging control was 95.7%. In our institution, 77 patients were included in the study. The mean age was 53.2 years. The median hospital stay was 4.92 hours. For the clinical follow-up, information on 47 patients was obtained. An improvement in pre-treatment symptoms was described in 58%, with general symptomatic control of 97%. The tumor-control rate was 95%, and there were statistically significant differences in six of the nine Short Form-36 scale domains.

Conclusion:
GKR is an effective, safe, and cost-effective technique that offers a high degree of symptomatic and tumor size control in patients with GJT.
Analysis of the influence of groove welds of oxy-acetylene welding joints on tensile strength and microstructure on steel ST 37
Authors: Nugroho Fajar , Muga Yohanes Fernando Leo , Setiabudi Dedet Hermawan , Sudarmanto Sudarmanto 
Published: March 2024

In this study, the authors conducted a study on the analysis of the effect of oxy-acetylene welding joints on tensile strength and microstructure in the HAZ and weld metal areas on st 37 steel plates. The results of this study indicate that the average value of the highest tensile strength value is at V groove weld with the average strength of the welded joint is 4.796 kgf/mm2. While the lowest tensile stress is on the I groove weld of 4.674 kgf/mm2. Meanwhile, from the microstructure test, it can be seen that in the HAZ area each groove. Microstructure in the HAZ area shows that the double V groove weld types are fine ferrite, coarse pearlite and martensite. In type V groove weld the structures formed are ferrite, coarse pearlite and martensite. In type I groove weld the structures formed are ferrite, grain boundary ferrite and fine pearlite. Whereas in the weld metal area, and the results of the microstructure test of the weld area on the V seam, it shows a dense microstructure arrangement, the arrangement is identical to pearlite (dark color) so that the specimen is harder.
Approach towards psoas syndrome risk modeling in preoperative planning for THA
Authors: Berger Luisa , Tokunaga Kunihiko , Radermacher Klaus 
Published: March 2024

Psoas syndrome after THA has received much attention in recent years. In some cases, the cause of pain cannot be found in a critical overhang of the implant cup, but is mainly unknown. We developed an approximation of modeling the medial part of the tendon of m. iliacus in 201 THA patients. We found length changes of the tendon of 7,73 mm ± 8,55 mm (range: -26,37 mm to 30,30 mm) and angular changes at the PSIS of 2,58 ° ± 1,72 ° (range: 0 to 7,91 °) and at the lesser trochanter of 10,53 ° ± 7,70 ° (range: 0,27 ° to 41,19 °). Furthermore, we identified 19 cases in whom the tendon wrapped over different bony structures than the acetabular region.Hence, we think that the m. iliacus tendon should be considered for analysis of risk factors in the preoperative planning process for THA.
Measured Resection and Gap Balancing Techniques Result in Similar Femoral Component Rotations Regardless of Preoperative Coronal Deformity: A Database Analysis of 3922 Cases
Authors: Hickey Matthew , Khan Asim , Baines Joseph , Allen David J , Welsh Findlay , Deep Kamal , Ewen Alistair , Leitner François , Hodgson Antony J. , Picard Frederic 
Published: March 2024

A common goal in total knee arthroplasty (TKA) is to obtain collateral ligament balance in both flexion and extension while maintaining neutral overall coronal alignment. Femoral component rotation is a key variable in achieving this goal. There are two prominent techniques used in TKA to determine implant orientation, measured resection and gap balancing, but there is some controversy over which technique is superior. At our institution, we regularly use both techniques over a wide range of patients with varying degrees of preoperative coronal deformity. We therefore asked, using intraoperative measurements from a surgical navigation system, can we detect significant differences in external rotation of the femoral component between measured resection and gap balancing techniques, and do any such differences occur more frequently or at higher levels at particular values of preoperative coronal deformity?We analysed 3922 navigated TKA cases undertaken at our institution which had complete measurements of preoperative overall coronal alignment and external rotation of the femoral component relative to the dorsal condyles line. We then compared cases using measured resection to those using the gap balancing technique, stratifying patients by degree of preoperative coronal deformity and applying a two-sample t-test.A total of 1969 cases that used measured resection and 1953 cases that used the gap balancing techniques were identified. We found no significant differences between the two techniques across most of the preoperative coronal deformity groupings, though small differences were detected in two specific subgroups: the femoral component was slightly more externally rotated in the measured resection cohort when the preoperative coronal deformity was between neutral and 50 valgus (mean ± standard deviation - measured resection: 3.60 ± 1.10, gap balancing: 3.00 ± 1.10, p &lt; 0.00625) and between 50 valgus and 100 valgus (measured resection: 4.30 ± 1.40, gap balancing: 3.70 ± 1.30, p &lt; 0.00625).This study has shown that there were essentially no substantial differences between the external rotation of the femoral component between the gap balancing and measured resection techniques regardless of the degree of preoperative coronal deformity. Overall, we feel that surgical decisions regarding which technique to use should be based more on any correlations with other patient outcome measures that may be better elucidated in future studies.
Automatic Glenoid Bone Loss Detection and Quantification in Shoulder CT Scans
Authors: Haimi Avichai , Safran Ori , Beyth Shaul , Joskowicz Leo 
Published: March 2024

Estimation of glenoid bone loss following shoulder dislocation in a CT scan is often required to determine the appropriate surgery needed to restore shoulder stability [1]. Currently, the best method for measuring glenoid bone loss has not been universally defined, so various methods have been proposed [2,3]. They can be grouped into linear-based (most methods) and area-based measurement methods, without (standalone) or with a comparison with the healthy contralateral glenoid, which is not always included in the CT scan. In all cases, the measurements are performed manually, which is time-consuming, requires expertise, and is subject to observer variability.This paper presents a novel automatic standalone linear-based method for glenoid bone loss quantification in shoulder CT scans.
Can thigh circumference predict thigh muscle volume? -Analysis using deep learning-
Authors: Kono Sotaro , Uemura Keisuke , Mazen Soufi , Iwasa Makoto , Takashima Kazuma , Hamada Hidetoshi , Otake Yoshito , Takao Masaki , Sato Yoshinobu , Okada Seiji , Sugano Nobuhiko 
Published: March 2024

Atrophy of thigh muscles significantly affects patients with hip diseases, thus quantifying the muscle volume can play an important role. Thigh circumference measurement has been used to predict thigh muscle volumes and atrophy. However, the validity of the measurement level, impact of error, and the relationship between each thigh muscle volumes at each measurement level remain not fully evaluated. In this study, we aimed to clarify the relationship between thigh circumference and the cross-sectional area (CSA) of each muscles using the deep learning model for automatic segmentation of the skin and muscles from CT images.Using 3D models, the thigh circumference and the CSAs of each muscle were measured at 0 cm to 20 cm above the superior aspect of the patella with 1 cm increment. evaluate the correlation between thigh circumference and CSAs.Thigh circumference tends to increase from distal to proximal, and for muscle’s CSA to increase as well. A strong correlation between muscle CSA and thigh circumference was observed above 5-10 cm, with a maximum correlation observed with the entire thigh muscle at 12 cm. Similar correlations were also observed around the level of maximum correlation. The correlation coefficients suggest that the measurement level should be adjusted for individual muscles. The correlation coefficients near the level of maximum correlation were almost equal, indicating that the influence of measurement level error is likely minimal.
Improved Prediction of Postoperative Knee Function Using Preoperative Patient Factors and Intraoperative Measures of Bony Resection, Ligament Release, and Implant Alignment in Total Knee Arthroplasty: A Database Analysis of 363 Cases
Authors: Hickey Matthew D , Khan Asim , Baines Joseph , Allen David , Welsh Findlay , Deep Kamal , Ewen Alistair , Leitner François , Hodgson Antony J , Picard Frederic 
Published: March 2024

Total knee arthroplasty (TKA) is a common approach to treating end-stage osteoarthritis of the knee while relieving pain and restoring joint function. However, the procedure has produced variations in postoperative outcomes, with up to 20% of patients left dissatisfied. Therefore, it is important to understand the preoperative and intraoperative factors that drive knee function post-TKA. Using intraoperative data acquired from a surgical navigation system and matched with patient pre- and postoperative data, this study aimed to identify preoperative and intraoperative predictors of PROMs measured using the Oxford Knee Score (OKS) at 1-year follow-up.We analysed 363 cases of navigated TKA at our institution and matched them to preoperative and postoperative patient clinical records including age at index surgery, BMI, sex, presence of co-morbidities, EQ5D anxiety/depression score, and preoperative and postoperative OKS. Starting with a base model of 26 predictor variables, a linear regression model with backward elimination was used to identify predictors of postoperative OKS on a training set of 290 patients. 73 patients (20%) were randomly set aside to use as validation. We then used the remaining predictor variables to train two additional regression models: a Support Vector Machine (SVM) and a Boosted Decision Tree then calculated the coefficient of determination (R2) and percent of patients that where the postoperative OKS was correctly identified within the minimally important clinical difference of 4.9 when the models were applied to the validation set.Of the 26 predictor variables, 10 predictors remained in the final model following backwards elimination, including four that were directly under the control of the surgeon. The R2 of the linear regression, SVM, and XGBoost models were 0.37, 0.30, and 0.29 respectively within the validation set. Percentages of patients with correctly predicted OKS within the MICD ranged from 52% to 57% (linear regression to SVM).In this study, we identified sets of preoperative and intraoperative factors which are partially predictive of postoperative OKS at 1-year follow-up. Post-operative prediction models such as the models presented here will help to guide continued research into which intraoperative variables, including bony resection depths, implant alignment, and whether to do ligament releases in surgery, most affect implant function post-TKA and to inform patients and clinicians of possible clinical outcomes.
EKSPLORASI AGEN ANTIBAKTERI EKSTRAK SPONS LAUT YANG DIAMBIL DARI PERAIRAN SEKITAR PLTU PAITON PROBOLINGGO
Authors: Maisaroh Dian Sari , Sa'adah Nor , Sakhi Hermalita Azkiyah 
Published: March 2024

Penelitian ini bertujuan untuk mengetahui aktivitas antibakteri dari spons laut yang diambil dari Perairan PLTU Paiton terhadap bakteri patogen Staphylococcus aureus, Vibrio parahaemolyticus, Escherichia coli dan Escherichia coli MDR (Multi Drug Resistant). Penelitian ini menggunakan metode experimental laboratory. Sampel yang ditemukan berjumlah 3 spons dan dimaserasi menggunakan pelarut metanol dengan pengulangan 3 kali. Hasil pasta ekstrak spons diujikan dengan metode difusi cakram terhadap bakteri patogen S. aureus, V. parahaemolyticus, E. coli dan E. coli MDR. Uji antibakteri menggunakan konsentrasi 10 mg/ml dengan pengulangan 2 kali. Hasil menunjukkan bahwa PPJT05 menghasilkan zona hambat lebih dari 2,4 mm pada keempat bakteri patogen yang diujikan. Ekstrak PPJT02 menghasilkan zona hambat tertinggi terhadap bakteri V. parahaemolyticus. Aktivitas antibakteri S. aureus tertinggi ditunjukkan oleh ekstrak PPJT05. Aktivitas antibakteri E. coli tertinggi ditunjukkan oleh ekstrak PPJT05. Aktivitas antibakteri E. coli MDR tertinggi ditunjukkan oleh ekstrak PPJT05. Ekstrak PPJT03 tidak menunjukkan keaktifan terhadap bakteri E. coli MDR meskipun ekstrak ini aktif terhadap bakteri lainnya. Ekstrak PPJT02, PPJT03 dan PPJT05 memiliki senyawa antibakteri berspektrum luas ditandai dengan kemampuan zona hambat terhadap bakteri gram positif dan gram negatif.
Kata Kunci: Antibakteri, Spons, S. aureus, V. parahaemolyticus, PLTU Paiton.
EL PROBLEMA DE LA OBLIGACIÓN POLÍTICA EN SITUACIONES DE INJUSTICIAS ECONÓMICAS Y SOCIALES: UNA RESPUESTA DESDE UNA TEORÍA DE MÚLTIPLES PRINCIPIOS
Authors: Magoja Eduardo Esteban 
Published: March 2024

El problema de la obligación política, esto es, el tipo de vínculo que existe entre los ciudadanos y la comunidad política en la que ellos son miembros, engloba una buena cantidad de subtemas de enorme complejidad. Uno de estos es la cuestión acerca de si las personas que no gozan de un reparto apropiado de bienes y cargas tienen el deber de someterse a la autoridad del derecho. Muchose ha escrito sobre los requisitos que debe satisfacer la distribución para ser justa y generar obediencia; pero no se suele examinar la posibilidad de que el derecho sea capaz de conservar su fuerza normativa en casos de injusticia (no extrema). En este trabajo se asume el desafío de abordar aquel punto complejo, el cual es de especial interés en el contexto de los Estados democráticos latinoamericanos. Mediante una combinación de la teoría del fair play, el deber de apoyar las instituciones justas y un principio de bien común (una teoría de múltiples principios) se buscará defender la tesis de que incluso en esquemas justos o casi justos, dondela distribución de bienes y cargas puede resultar un tanto deficitaria, prima facie los ciudadanos tienen un deber de obediencia hacia el derecho.
Analisis Kemampuan Pemecahan Masalah Matematis Siswa SMA dalam Menyelesaikan Soal Cerita SPLTV
Authors: Lilisantika  , Roesdiana Lessa 
Published: March 2024

Dalam pembelajaran, sebagian besar siswa SMA kurang memahami langkah-langkah penyelesaian masalah matematika khususnya pada materi Sistem Persamaan Linear Tiga Variabel (SPLTV). Soal cerita dapat menjadi salah satu alternatif untuk mengukur kemampuan pemecahan masalah dan penguasaan materi siswa. Tujuan dari penelitian ini adalah menganalisis kemampuan pemecahan masalah matematis siswa saat menyelesaikan soal-soal SPLTV serta mengetahui kesulitan dan faktor yang mempengaruhinya. Jenis penelitian ini adalah deskriptif kualitatif. Subjek penelitian ini adalah siswa kelas X SMAN 96 Jakarta yang berjumlah 59 siswa. Metode pengumpulan data dengan tes kemampuan pemecahan masalah matematis, wawancara dan dokumentasi. Metode analisis data melalui reduksi data, penyajian data, dan penarikan kesimpulan. Berdasarkan hasil penelitian, rata-rata kemampuan pemecahan masalah matematis siswa berdasarkan langkah Polya adalah 48,19 dan berada pada kategori cukup baik. Hasil penelitian ini menunjukkan bahwa kemampuan pemecahan masalah matematis siswa dibagi menjadi tiga kriteria, yaitu: (1) Siswa dengan kemampuan tinggi dapat memenuhi tiga indikator pemecahan masalah, (2) Siswa dengan kemampuan sedang dapat memenuhi dua indikator. pemecahan masalah, (3) Siswa dengan kemampuan rendah hanya dapat menyelesaikan satu indikator pemecahan masalah. Penyebabnya adalah siswa kesulitan memahami soal, kesulitan melakukan operasi hitung sehingga tidak dapat menyelesaikan penyelesaian dengan benar, dan tidak terbiasa memeriksa kembali jawaban. Faktor yang mempengaruhi diantaranya kurang aktif dalam proses pembelajaran dan kurang memperhatikan guru ketika menjelaskan.
Minat Belajar Matematika di Sekolah Menengah Pertama pada Penerapan Kurikulum Merdeka
Authors: Dhani Hamdhani , Haerudin Haerudin 
Published: March 2024

Penelitian ini bertujuan untuk menganalisis minat belajar matematika peserta didik pada penerapan Kurikulum Merdeka di Sekolah Menengah Pertama (SMP). Pada penelitian ini menggunakan kualitatif dengan metode deskriptif. Populasi pada penelitian ini adalah Sekolah Menengah Pertama 2 Telukjambe Timur Karawang tahun ajaran 2022/2023. Teknik pengambilan sampel yang digunakan adalah purposive sampling. Sampel yang digunakan yaitu peserta didik kelas VIIIC dengan total 41 peserta didik. Teknik pengumpulan data pada penelitian ini adalah pemberian instrumen non tes berupa angket terkait minat belajar matematika. Instrumen non-tes angket yang diberikan berjumlah 34 pernyataan dengan memuat 4 indikator minat belajar yaitu perasaan senang, ketertarikan untuk belajar, perhatian saat belajar, dan keterlibatan dalam belajar. Teknik analisis data yang digunakan adalah rumus persentase hasil jawaban peserta didik pada indikator minat belajar matematika. Hasil penelitian ini menunjukkan hampir setengah peserta didik memiliki minat belajar matematika dengan rata-rata persentase sebesar 32%. Dengan demikian peserta didik pada Sekolah Menengah Pertama 2 Telukjambe Timur Karawang memiliki hampir setengahnya minat belajar matematika.