bluuebunny/crossref_metadata_2025_split huggingface dataset:
Adherence to PRISMA 2020 reporting guidelines and scope of systematic reviews published in nursing: A cross‐sectional analysis
Authors: Carlo Torres Gian , Ledbetter Leila , Cantrell Sarah , Alomo Anna Rita L. , Blodgett Thomas J. , Bongar Maria Victoria , Hatoum Sandy , Hendren Steph , Loa Ritzmond , Montaña Sherihan , Francis Sumile Earl , Turner Kathleen M. , Relf Michael V. 
Published: March 2024

AbstractIntroductionSystematic reviews are considered the highest level of evidence that can help guide evidence‐informed decisions in nursing practice, education, and even health policy. Systematic review publications have increased from a sporadic few in 1980s to more than 10,000 systematic reviews published every year and around 30,000 registered in prospective registries.MethodsA cross‐sectional design and a variety of data sources were triangulated to identify the journals from which systematic reviews would be evaluated for adherence to Preferred Reporting Items for Systematic Reviews and Meta‐Analyses (PRISMA) 2020 reporting guidelines and scope. Specifically, this study used the PRISMA 2020 reporting guidelines to assess the reporting of the introduction, methods, information sources and search strategy, study selection process, quality/bias assessments, and results and discussion aspects of the included systematic reviews.ResultsUpon review of the 215 systematic reviews published in 10 top‐tier journals in the field of nursing in 2019 and 2020, this study identified several opportunities to improve the reporting of systematic reviews in the context of the 2020 PRISMA statement. Areas of priority for reporting include the following key areas: (1) information sources, (2) search strategies, (3) study selection process, (4) bias reporting, (5) explicit discussion of the implications to policy, and lastly, the need for (6) prospective protocol registration.DiscussionThe use of the PRISMA 2020 guidelines by authors, peer reviewers, and editors can help to ensure the transparent and detailed reporting of systematic reviews published in the nursing literature.Clinical RelevanceSystematic reviews are considered strong research evidence that can guide evidence‐based practice and even clinical decision‐making. This paper addresses some common methodological and process issues among systematic reviews that can guide clinicians and practitioners to be more critical in appraising research evidence that can shape nursing practice.
Trajectories of offending over 9 years after youths' first arrest: What predicts who desists and who continues to offend?
Authors: Cauffman Elizabeth , Beardslee Jordan , Sbeglia Colleen , Frick Paul J. , Steinberg Laurence 
Published: March 2024

AbstractAntisocial and illegal behavior generally declines as youth approach adulthood, but there is significant individual variation in the timing of the peak and decline of offending from adolescence to young adulthood. There are two primary research questions in the present study. First, are there subgroups of youth who follow similar patterns of offending over the nine years after their first arrest? Second, what baseline factors predict which youth will follow each pattern of offending? Data were drawn from the Crossroads study, which includes a sample of racially and ethnically diverse boys who were interviewed regularly for 9 years following their first arrest. Boys were between 13 and 17 years old at the start of the study and were approximately 24‐25 years old at the final interview. Trajectories were measured with youths' self‐reported offending using latent class growth analysis (LCGA). Results indicated that there were four subgroups of youth: a stable low group (55%), an escalating group (23%), a short‐term recidivist group (15%), and a persistently high group (7%). Several baseline factors distinguished the groups. In particular, the results indicated that youth who were informally processed after their first arrest were more likely to be in the low offending group than any of the other LCGA groups. Age at first arrest, peer delinquency, exposure to violence, substance use, callous‐unemotional traits, physical aggression, and perceptions of police legitimacy were also significantly related to group membership. Results suggest that certain risk factors identified after youths' first arrest may predict which youth continue to offend and which desist.
RELTRAD2: Refining the State of the Art of Religious Classification by Reconsidering the Categorization of Nondenominational Respondents
Authors: Gaghan Josh , Eagle David 
Published: March 2024

AbstractRELTRAD is a major religious taxonomy used by a large number of researchers. Although criticisms have been raised about its utility, improving the algorithm to capture contemporary religious dynamics is important given its widespread use. The present RELTRAD taxonomy classifies more religiously active nondenominational respondents as Conservative Protestants and codes the remainder as missing data. A growing number of Americans indicate they are either nondenominational or only Christian or Protestant, which means using RELTRAD in its existing form codes a nonrandom and increasingly large number of respondents with a missing value for religious affiliation (growing from 2 percent to 5 percent of the US General Social Survey (GSS) sample between 2000 and 2018). Using a machine learning algorithm to predict the likely religious tradition of nondenominational respondents, we demonstrate the shortcomings of this approach and introduce a new coding scheme, RELTRAD2, which classifies nondenominational respondents who report a Black racial identity as Black Protestant, non‐Black respondents who never attend religious services as Mainline Protestant, and the remainder as Conservative Protestant. Code to derive RELTRAD2 from the GSS is provided.
Neurokinin‐1 receptor antagonist aprepitant regulates autophagy and apoptosis via ROS/JNK in intrahepatic cholangiocarcinoma
Authors: Yang Yang , Cao Xueyan , Wang Yuting , Wu Xinyu , Zhou Ping , Miao Lin , Deng Xueting 
Published: March 2024

AbstractBackgroundIntrahepatic cholangiocarcinoma (iCCA) has a poor prognosis and limited treatment options. Aprepitant, a selective NK‐1R antagonist, can inhibit the growth of various tumours in vitro and in vivo. However, it remains unclear whether aprepitant has cytotoxic effects on iCCA.MethodsWe measured the expression of SP/NK‐1R in clinical samples of iCCA by immunohistochemistry. Then, we detected the cytotoxic effects of aprepitant on iCCA cells via MTT, EdU and colony formation assay. We constructed a subcutaneous xenograft model of BALB/c nude mice by using HCCC‐9810 and RBE cell lines to explore the effects of aprepitant in vivo. To elucidate the potential mechanisms, we explored the pro‐apoptotic effect of aprepitant by flow cytometric, western blotting, ROS detection and JC‐1 staining. Furthermore, we detected the autophagic level of HCCC‐9810 and RBE by western blotting, mRFP‐eGFP‐LC3 adenovirus transfection and electron microscope.ResultsSP/NK‐1R is significantly expressed in iCCA. Aprepitant inhibited human iCCA xenograft growth and dose‐dependently decreased the viability of RBE and HCCC‐9810 cells. Aprepitant‐induced mitochondria‐dependent apoptosis through ROS/JNK pathway. Additionally, pretreatment with z‐VAD‐fmk partly reversed the effect of aprepitant on cell viability, while NAC completely attenuated the cytotoxic effects of aprepitant in vitro. Furthermore, we observed the dynamic changes of autophagosome in RBE and HCCC‐9810 cells treated with aprepitant.ConclusionSP/NK‐1R signalling is significantly activated in iCCA and promotes the proliferation of iCCA cells. By contrast, aprepitant can induce autophagy and apoptosis in iCCA cells via ROS accumulation and subsequent activation of JNK.
FGF21 protects against ischaemia reperfusion injury in normal and fatty livers
Authors: Ma Yong , Singhal Garima , Chan Suzanne S. , Wang Chaoqun , Yu Hongjun , Yin Bing , Pang Jing , Malvar Grace , Nasser Imad , Mather Marie L. , Maratos‐Flier Eleftheria 
Published: March 2024

AbstractBackgroundLiver ischaemia/reperfusion (I/R) injury, which is an inevitable clinical problem of liver resection, liver transplantation and haemorrhagic shock. Fibroblast growth factor 21 (FGF21) was intimately coupled with multiple metabolic processes and proved to protect against apoptosis and inflammatory response in hepatocytes during hepatic I/R injury. However, the regulatory mechanisms of FGF21 in hepatic I/R injury remains unknown. Therefore, we hypothesize that FGF21 protects hepatic tissues from I/R injury.MethodsBlood samples were available from haemangiomas patients undergoing hepatectomy and murine liver I/R model and used to further evaluate the serum levels of FGF21 both in humans and mice. We further explored the regulatory mechanisms of FGF21 in murine liver I/R model by using FGF21‐knockout mice (FGF21‐KO mice) and FGF21‐overexpression transgenic mice (FGF21‐OE mice) fed a high‐fat or ketogenic diet.ResultsOur results show that the circulating levels of FGF21 were robustly decreased after liver I/R in both humans and mice. Silencing FGF21 expression with FGF21‐KO mice aggravates liver injury at 6 h after 75 min of partial liver ischaemia, while FGF21‐OE mice display alleviated hepatic I/R injury and inflammatory response. Compared with chow diet mice, exogenous FGF21 decreases the levels of aminotransferase, histological changes, apoptosis and inflammatory response in hepatic I/R injury treatment mice with a high‐fat diet. Meanwhile, ketogenic diet mice are not sensitive to hepatic I/R injury.ConclusionsThe circulating contents of FGF21 are decreased during liver warm I/R injury and exogenous FGF21 exerts hepatoprotective effects on hepatic I/R injury. Thus, FGF21 regulates hepatic I/R injury and may be a key therapeutic target.
Histological characterization of liver involvement in systemic mastocytosis
Authors: Rossignol Julien , Canioni Danielle , Aouba Achille , Bulai‐Livideanu Cristina , Barete Stéphane , Lancesseur Charles , Polivka Laura , Madrange Marine , Ballul Thomas , Neuraz Antoine , Greco Celine , Agopian Julie , Brenet Fabienne , Dubreuil Patrice , Lemal Richard , Tournilhac Olivier , Terriou Louis , Launay David , Bouillet Laurence , Gourguechon Clément , Frenzel Laurent , Meni Cécile , Gaudy‐Marqueste Caroline , Gousseff Marie , Le Mouel Edwige , Hamidou Mohamed , Neel Antoine , Ranta Dana , Jaussaud Roland , Guilpain Philippe , Molina Thierry J , Bruneau Julie , Lhermitte Ludovic , Garcelon Nicolas , Javier Rose‐Marie , Pelletier Fabien , Castelain Florence , Retornaz Frederique , Cabrera Quentin , Zunic Patricia , Gourin Marie Pierre , Wierzbicka‐Hainaut Ewa , Viallard Jean François , Lavigne Christian , Hoarau Cyrille , Durieu Isabelle , Heiblig Maël , Dimicoli‐Salazar Sophie , Torregrosa‐Diaz Jose M , Soria Angèle , Arock Michel , Lortholary Olivier , Bodemer Christine , Pol Stanislas , Mallet Vincent , Hermine Olivier , Damaj Ghandi ,   on behalf the CEREMAST Network
Published: March 2024

AbstractBackground and AimsSystemic mastocytosis (SM) is characterized by the accumulation of atypical mast cells (MCs) in organs. Liver histology of SM has been marginally described and accurate histological classification is critical, given the consequences of aggressive SM diagnosis. We aimed to describe the histological features associated with liver SM using updated tools.MethodsUsing the database of the French Reference Centre for Mastocytosis, we retrospectively identified patients with a liver biopsy (LB) and a diagnosis of SM. All LB procedures were performed according to the local physician in charge and centrally reviewed by an expert pathologist.ResultsA total of 28 patients were included: 6 had indolent SM, 9 had aggressive SM, and 13 had SM with an associated hematologic neoplasm. Twenty‐five (89%) patients presented hepatomegaly, and 19 (68%) had portal hypertension. The LB frequently showed slight sinusoid dilatation (82%). Fibrosis was observed in 3/6 indolent SM and in almost all advanced SM cases (21/22), but none of them showed cirrhosis. A high MC burden (>50 MCs/high‐power field) was correlated with elevated blood alkaline phosphatase levels (p = .030). The presence of portal hypertension was associated with a higher mean fibrosis grade (1.6 vs. 0.8 in its absence; p = .026). In advanced SM, the presence of nodular regenerative hyperplasia (NRH) was associated with decreased overall survival (9.5 vs. 46.3 months, p = .002).ConclusionsMC infiltration induced polymorphic hepatic lesions and the degree of fibrosis is associated with portal hypertension. NRH identifies a poor prognosis subgroup of patients with advanced SM. Assessing liver histology can aid in SM prognostic evaluation.
Queue‐jumping arguments
Authors: Aberdein Andrew , Pike Kenneth R. 
Published: March 2024

AbstractA queue‐jumping argument concludes that some course of action is impermissible by likening it to the presumptively impermissible act of jumping a queue. Arguments of this sort may be found in a disparate range of contexts and in support of policies favoured by both left and right. Examples include arguments against private education and private health care but also arguments against accommodations for learning disabilities, refugee resettlement, and birthright citizenship. We infer that, although queue‐jumping arguments are strictly analogies, they constitute a sufficiently distinct class of arguments to justify their separate treatment. The paper proposes an argumentation scheme for queue‐jumping arguments and demonstrates its applicability to some existing arguments of this type.
Sociolinguistic competence and varietal repertoires in a second language: A study on addressee‐dependent varietal behavior using virtual reality
Authors: Wirtz Mason A. , Pfenninger Simone E. , Kaiser Irmtraud , Ender Andrea 
Published: March 2024

AbstractThe present study takes a variationist perspective to explore the varietal repertoires of adult learners of German as a second language (L2), that is, their variable use of standard German, Austro‐Bavarian dialect, and mixture varieties. Forty L2 learners completed a virtual reality task involving interactions with dialect‐speaking and standard‐German‐speaking interlocutors. Using Bayesian multilevel modeling, the goal was to explore differential outcomes in the acquisition of sociolinguistic competence by determining whether participants adjusted their varietal behavior to match that of the interlocutor (i.e., varietal convergence). The results show that there were no interindividual addressee‐dependent convergence tendencies. A holistic person‐centered analysis of individual learners’ intraspeaker variation revealed that only select L2 learners adjusted their usage patterns but did not entirely invert their usage of dialect and standard language as a function of the variety of the interlocutor. Introspective qualitative data speak to potential drivers behind the differential development of L2 (multi)varietal repertoires.
First biochemical and behavioural analysis of the response of the scorpion Urophonius brachycentrus (Thorell: 1876) upon exposure to an organophosphate
Authors: Garcia Carlos F. , Ojanguren Andrés , Seoane Analía , Iuri Hernan , Gambaro Rocio , Molina Gabriel , Laino Aldana 
Published: March 2024

AbstractScorpionism is an increasing public health problem in the world. Although no specific methodology or product is currently available for the control of those arachnids, the use of insecticides could be an effective tool. Chlorpyrifos is one of the insecticides used, but to date, whether scorpions recognise surfaces with that insecticide and how it affects their physiology and/or biochemistry is unknown. In the present study, we observed that scorpions recognise surfaces with 0.51 and 8.59 μg/cm2 of chlorpyrifos and avoid those areas. The 0.51 μg/cm2 concentration produced a decrease in acetylcholinesterase and an increase in catalase, superoxide dismutase and glutathione S‐transferase, whereas the 8.59 μg/cm2 concentration evoked a decrease in acetylcholinesterase and an increase in catalase and glutathione S‐transferase. Using the comet assay, we observed that the insecticide at 0.17, 0.51 and 8.59 μg/cm2 caused DNA damage. Finally, we found that the insecticide does not generate significant variations in glutathione peroxidase, glutathione reductase, the amount of protein or lipid peroxidation. The present results offer a comprehensive understanding of how scorpions respond, both at the biochemical and behavioural levels, when exposed to insecticides.
Utilization of immediate extubation in a multidisciplinary pathway for pediatric liver transplantation associated with improved postoperative outcomes
Authors: Goldstein Matthew A. , Karlik Joelle , Kamat Pradip P. , Lo Denise J. , Liu Katie , Gilbertson Laura E. 
Published: March 2024

AbstractBackgroundImmediate extubation is becoming more common in liver transplantation. However, limited data exist on how to identify pediatric patients with potential for successful immediate extubation and how this intervention may affect recovery.MethodsThis retrospective review evaluated patients who underwent liver transplantation from 2015 to 2021 at Children's Healthcare of Atlanta. Preoperative status and intraoperative management were evaluated and compared. Outcomes comprised thrombosis, surgical reexploration, retransplantation, as well as reintubation, high flow nasal cannula (HFNC) usage, postoperative infection, the length of stay (LOS), and mortality.ResultsA total of 173 patients were analyzed, with 121 patients (69.9%) extubated immediately. The extubation group had older age (median 4.0 vs 1.25 years,p = .048), lower PELD/MELD (28 vs. 34,p = .03), decreased transfusion (10.2 vs. 41.7 mL/kg,p < .001), shorter surgical time (332 vs. 392 min,p < .001), and primary abdominal closure (81% vs. 40.4%,p < .001). Immediate extubation was associated with decreased HFNC (0.21 vs. 0.71 days,p = .02), postoperative infection (9.9% vs. 26.9%,p = .007), mortality (0% vs. 5.8%,p = .036), and pediatric intensive care unit LOS (4.7 vs. 11.4 days,p < .001). The complication rate was lower in the extubation group (24.8% vs. 36.5%), but not statistically significant.ConclusionsApproximately 70% of patients were able to be successfully extubated immediately, with only 2.5% requiring reintubation. Those immediately extubated had decreased need for HFNC, lower infection rates, shorter LOS, and decreased mortality. Our results show that with proper patient selection and a multidisciplinary approach, immediate extubation allows for improved recovery without increased respiratory complications after pediatric liver transplantation.
A systematic review of public policy implementation during the Covid‐19 pandemic: Current topics and future directions
Authors: de Oliveira Lemos Novato Valeria , Toscano Cristiana Maria , da Rocha Soares Ferreira Vicente , Patel Shivani 
Published: March 2024

AbstractThe Covid‐19 pandemic greatly impacted global public policy implementation. There is a lack of research synthesizing the lessons learned during Covid‐19 from a policy perspective. A systematic review was conducted following PRISMA guidelines to examine the literature on public policy implementation during the Covid‐19 pandemic in order to gain comprehensive insights into current topics and future directions. Five clusters of topics were identified: lessons from science, crisis governance, behavior and mental health, beyond the crisis, and frontlines and trust. Extensive collaboration among public health departments emerged as a significant research theme. Thirty recommendations for future research were identified, including the examination of frontline worker behavior, the use of just tech in policy implementation, and the investigation of policies driving improvements in global public health. The findings indicate that current research on public policy implementation during the Covid‐19 pandemic extends beyond health and economic crisis‐related policies. However, further studies in a post‐pandemic context are needed to validate the identified topics and future directions.
Impact of dental sedation treatment on the oral health‐related quality of life of distressed young children: A secondary analysis of a randomized clinical trial
Authors: Corrêa‐Faria Patrícia , Paiva Saul Martins , Costa Luciane Rezende 
Published: March 2024

AbstractIntroductionLittle is known regarding the impact of dental treatment under sedation on distressed young children's oral health‐related quality of life (OHRQoL).AimTo evaluate the impact of dental treatment under sedation on the OHRQoL of children and their families.MethodsCaregivers of two‐to‐six‐year‐old children answered the Brazilian version of the Early Childhood Oral Health Impact Scale (B‐ECOHIS): (1) before treatment under sedation (T0), (2) two weeks (T1) and (3) 3 months after the completion of treatment (T2). A global transition judgment was included in the posttreatment evaluations to determine the perception of changes in OHRQoL after dental treatment. Bivariate analysis was performed. Changes in scores and effect sizes (ES) were calculated.ResultsReductions were found at both posttreatment evaluations in the total B‐ECOHIS scores (median [25th–75th percentile] at T0: 14 [9.8–21.7]; T1: 2.0 [0.0–5.1]; T2: 2.0 [0.0–6.7]); “child impact” section (T0: 8.8 [4.0–13.1]; T1: 0.0 [0.0–2.2]; T2: 0.0 [0.0–4.3]) and “family impact” section (T0: 6.0 [4.0–8.5]; T1: 0.0 [0.0–2.0]; T2: 0.0 [0.0–2.0]) (≤0.001; large ES). In 92.3% of cases at T1 and 88.3% at T2, caregivers reported that their child's oral health improved considerably.ConclusionDental treatment under sedation significantly improved the OHRQoL of the children and their families.
Jealousy as a correlate of intimate partner homicide‐suicide versus homicide‐only cases: National Violent Death Reporting System, 2016–2020
Authors: Johnson Laura 
Published: March 2024

AbstractIntroductionThe objective of this study was to compare jealousy as a correlate of intimate partner homicide‐suicide cases to homicide‐only cases using data from the National Violent Death Reporting System (NVDRS), a state‐based surveillance system maintained by the Centers for Disease Control and Prevention. Jealousy is categorized as jealous feelings or distress over a current or former intimate partner's relationship or suspected relationship with another person.MethodsNVDRS data from a 5‐year period (2016–2020) was used to estimate frequencies and identify significant differences in jealousy and other sociodemographic, mental health, relationship, and incident‐related correlates of intimate partner homicide‐suicide compared to homicide‐only cases. Cases were included if they involved an intimate partner single homicide or a single homicide followed by suicide.ResultsThe study sample included 5335 cases (intimate partner homicide‐suicide n = 1402; homicide‐only n = 3933). A significantly higher percentage of intimate partner homicide‐suicide cases reported jealousy preceding the event (9%) compared to homicide‐only cases (6%). Compared with homicide‐only cases, homicide‐suicide cases had 3.5 greater odds of recording jealousy as a precipitating event.ConclusionFindings suggest that intimate partner homicide‐suicide cases are distinct from homicide‐only cases both in terms of individual‐ and incident‐level and situational factors, including the presence of jealousy.