bluuebunny/crossref_metadata_2025_split huggingface dataset:
Hedging with physical or cash settlement under transient multiplicative price impact
Authors: Becherer Dirk , Bilarev Todor 
Published: March 2024

AbstractWe solve the superhedging problem for European options in an illiquid extension of the Black–Scholes model, in which transactions have transient price impact and the costs and strategies for hedging are affected by physical or cash settlement requirements at maturity. Our analysis is based on a convenient choice of reduced effective coordinates of magnitudes at liquidation for geometric dynamic programming. The price impact is transient over time and multiplicative, ensuring nonnegativity of underlying asset prices while maintaining an arbitrage-free model. The basic (log-)linear example is a Black–Scholes model with a relative price impact proportional to the volume of shares traded, where the transience for impact on log-prices is modelled like in Obizhaeva and Wang (J. Financ. Mark. 16:1–32, 2013) for nominal prices. More generally, we allow nonlinear price impact and resilience functions. The viscosity solutions describing the minimal superhedging price are governed by the transient character of the price impact and by the physical or cash settlement specifications. The pricing equations under illiquidity extend no-arbitrage pricing à la Black–Scholes for complete markets in a non-paradoxical way (cf. Çetin et al. (Finance Stoch. 14:317–341, 2010)) even without additional frictions, and can recover it in base cases.
Harms from Other People’s Gambling: Associations with an Individual’s Own Gambling Behaviours, Health Risk Behaviours, Financial Problems, General Health, and Mental Wellbeing
Authors: Wilson Charley , Butler Nadia , Quigg Zara 
Published: March 2024

AbstractThis study aimed to explore relationships between being an ‘affected other’ (AO) and an individual’s own gambling, health risk behaviours, financial problems, poor general health, and low mental wellbeing. A cross-sectional survey using representative and supplementary convenience samples was undertaken with 1234 residents of a British Island aged 16 + years. Being an AO was measured as having a partner or relative who has been gambling regularly in the past 12 months. PGSI was used to assess gambling severity. Health risk behaviours included: poor diet, low physical activity, daily smoking, and binge drinking. Other measures included experiencing financial problems, poor general health, and low mental wellbeing. Analyses were performed using χ2 and binary logistic regressions. 11.0% of participants were AOs. AOs were more likely to gamble at at-risk/problem-gambling levels and experience financial problems compared to those who were not affected others. The significant relationship between being an AO and low mental wellbeing was mediated by experiencing financial problems. The relationship between being an AO and engaging in two or more health risk behaviours was no longer significant after controlling for sociodemographics and an individual’s own gambling. The relationship between being an AO and poor general health was no longer significant after controlling for sociodemographics, health risk behaviours and an individual’s own gambling. AOs experienced risks to health and wellbeing, with findings not limited to AOs specifically with a relationship to an individual with problem-gambling. Therefore, support for AOs should be more widely available, aiming to address AOs’ needs holistically.
A systematic review of the inequality of health burdens related to climate change
Authors: Song Xinke , Zhang Shihui , Huang Hai , Ding Qun , Guo Fang , Zhang Yaxin , Li Jin , Li Mingyu , Cai Wenjia , Wang Can 
Published: March 2024

AbstractClimate change significantly impacts human health, exacerbating existing health inequalities and creating new ones. This study addresses the lack of systematic review in this area by analyzing 2440 publications, focusing on four key terms: health, disparities, environmental factors, and climate change. Strict inclusion criteria limited the selection to English-language, peer-reviewed articles related to climate health hazards, ensuring the relevance and rigor of the synthesized studies. This process synthesized 65 relevant studies. Our investigation revealed that recent research, predominantly from developed countries, has broadened its scope beyond temperature-related impacts to encompass diverse climate hazards, including droughts, extreme weather, floods, mental health issues, and the intersecting effects of Coronavirus Disease 2019. Research has highlighted exposure as the most studied element in the causal chain of climate change-related health inequalities, followed by adaptive capability and inherent sensitivity. The most significant vulnerabilities were observed among populations with low socioeconomic status, ethnic minorities, and women. The study further reveals research biases and methodological limitations, such as the paucity of attention to underdeveloped regions, a narrow focus on non-temperature-related hazards, challenges in attributing climate change effects, and a deficit of large-scale empirical studies. The findings call for more innovative research approaches and a holistic integration of physical, socio-political, and economic dimensions to enrich climate-health discourse and inform equitable policy-making.
Lipid peroxidation and stress-induced signalling molecules in systemic resistance mediated by azelaic acid/AZELAIC ACID INDUCED1: signal initiation and propagation
Authors: Priya Reddy Y. N. , Oelmüller Ralf 
Published: March 2024

AbstractSystemic acquired resistance protects plants against a broad spectrum of secondary infections by pathogens. A crucial compound involved in the systemic spread of the threat information after primary pathogen infection is the C9 oxylipin azelaic acid (AZA), a breakdown product of unsaturated C18 fatty acids. AZA is generated during lipid peroxidation in the plastids and accumulates in response to various abiotic and biotic stresses. AZA stimulates the expression of AZELAIC ACID INDUCED1 (AZI1), and a pool of AZI1 accumulates in the plastid envelope in association with AZA. AZA and AZI1 utilize the symplastic pathway to travel through the plasmodesmata to neighbouring cells to induce systemic stress resistance responses in distal tissues. Here, we describe the synthesis, travel and function of AZA and AZI1 and discuss open questions of signal initiation and propagation.
Adsorption of stable and labile emerging pollutants on activated carbon: degradation and mass transfer kinetic study
Authors: Díaz Eva , García Laura , Ordóñez Salvador 
Published: March 2024

AbstractThe design of adsorption processes for pharmaceuticals removal depends not only on the adsorption equilibrium but also on the mass transfer and adsorbate stability, being a problem still not solved the case of degradation products. By selecting different stable (amoxicillin, ciprofloxacin, carbamazepine and ibuprofen) and labile micropollutants (omeprazole) as case studies emerging pollutants, we have quantitatively analysed these effects on activated carbon. For stable compounds, the experimental data were fitted to equilibrium models to obtain information about the different adsorption mechanism depending on the characteristics of the molecules. Mass transfer effects were analysed for all the adsorbates, observing the control of intraparticle pore diffusion mechanism, since the effective pore diffusion coefficient is in the range from 10–8 to 10–10 cm2 h−1. As far as omeprazole is concerned, a kinetic model is proposed for predicting its degradation, identifying the reversibility of several degradation steps. The overall adsorption of OMP and derivates is calculated, observing the pore diffusion is considered as the rate-limiting step. For the first time, a combined model considering the chemical degradation and the adsorption of the degradation products is proposed and experimentally validated. This represents an important step in the modelling of processes leading to the purification of water from this type of pollutant.
Get out from my field! The role of agricultural crops in shaping the habitat selection by and suitability for the crested porcupine in Central Italy
Authors: Franchini Marcello , Frangini Lorenzo , Viviano Andrea , Filacorda Stefano , Stokel Giacomo , Mori Emiliano 
Published: March 2024

Abstract‘Agricultural pests’ is a locution used to indicate those wild species considered as dangerous to crops. The crested porcupine Hystrix cristata is a semi–fossorial rodent considered as one of the main agricultural pests by farmers in Italy. Assessing the role of agriculture in shaping the porcupine’s space use is of great importance to develop proper management and conservation strategies. The goal of this study was to quantify the degree of habitat selection by and suitability for porcupines in Central Italy to assess the potential influence of agricultural fields on the ecology of this rodent. The habitat suitability analysis was realized using presence–only data implemented in the MAXENT Software, while the habitat selection analysis was carried out using the Jacobs’ selectivity index. Our research revealed that croplands have an important role in the overall habitat suitability for porcupines. However, during the warm period, all habitats were used according to their availability. Conversely, orchards, vineyards, and olive groves were preferred during the cold period. Our findings suggest that the use of agricultural crops in accordance with their availability during the warm season and the preference shown for orchards, vineyards, and olive groves during the cold one, highlight that porcupine–famer negative interactions may occur in the area. The implementation of proper prevention measures is therefore strongly suggested, especially during the cold period, to reduce the potential impacts on agriculture.
Diagnosis and treatment of Paget’s disease of bone: position paper from the Italian Society of Osteoporosis, Mineral Metabolism and Skeletal Diseases (SIOMMMS)
Authors: Rendina D. , Falchetti A. , Diacinti D. , Bertoldo F. , Merlotti D. , Giannini S. , Cianferotti L. , Girasole G. , Di Monaco M. , Gonnelli S. , Malavolta N. , Minisola S. , Vescini F. , Rossini M. , Frediani B. , Chiodini I. , Asciutti F. , Gennari L. 
Published: March 2024

Abstract
Introduction
Paget’s disease of bone is a focal skeletal disorder causing bone deformities and impairing bone quality. Despite the prevalence of asymptomatic cases is increasing, the progression of the disease can lead to invalidating complications that compromise the quality of life. Doubts on clinical and therapeutic management aspects exist, although beneficial effects of antiresorptive drugs, particularly bisphosphonates are known. However, limited information is available from randomized controlled trials on the prevention of disease complications so that somewhat contrasting positions about treatment indications between expert panels from the main scientific societies of metabolic bone diseases exist. This task force, composed by expert representatives appointed by the Italian Society of Osteoporosis, Mineral Metabolism and Skeletal Diseases and members of the Italian Association of Paget’s disease of bone, felt the necessity for more specific and up to date indications for an early diagnosis and clinical management.

Methods
Through selected key questions, we propose evidence-based recommendations for the diagnosis and treatment of the disease. In the lack of good evidence to support clear recommendations, available information from the literature together with expert opinion of the panel was used to provide suggestions for the clinical practice.

Results and conclusion
Description of the evidence quality and support of the strength of the statements was provided on each of the selected key questions. The diagnosis of PDB should be mainly based on symptoms and the typical biochemical and radiological features. While treatment is mandatory to all the symptomatic cases at diagnosis, less evidence is available on treatment indications in asymptomatic as well as in previously treated patients in the presence of biochemical recurrence. However, given the safety and long-term efficacy of potent intravenous bisphosphonates such as zoledronate, a suggestion to treat most if not all cases at the time of diagnosis was released.
Psychological symptoms and brain activity alterations in women with PCOS and their relation to the reduced quality of life: a narrative review
Authors: Pinto J. , Cera N. , Pignatelli D. 
Published: March 2024

Abstract
Background
Polycystic ovary syndrome (PCOS) is the most common feminine endocrine disorder, characterized by androgen excess, ovulatory dysfunction, and polycystic ovarian morphology. The negative impact of symptoms on the quality of life (QoL) of patients is still not clear.

Purpose
The present review aimed at studying the impact of the symptoms, the psychological symptoms, and brain alterations in women with PCOS.

Methods
A systematic search was undertaken for studies that assessed the impact of PCOS symptoms on QoL, psychological symptoms, and brain alterations in PCOS patients.

Results
Most of the information about QoL came from psychometric studies, which used culture-based questionnaires. Alterations of sleep quality, body image, and mood disorders can negatively affect the QoL of the patients. Sexual satisfaction and desire were affected by PCOS. Brain imaging studies showed functional alterations that are associated with impairments of visuospatial working memory, episodic and verbal memory, attention, and executive function.

Conclusions
Several factors can negatively influence the quality of life of the patients, and they are directly related to hyperandrogenism and the risk of infertility. In particular, obesity, hirsutism, acne, and the fear of infertility can have a direct impact on self-esteem and sexual function. Metabolic and psychiatric comorbidities, such as mood, anxiety, and eating disorders, can affect the well-being of the patients. Moreover, specific cognitive alterations, such as impairments in attention and memory, can limit PCOS patients in a series of aspects of daily life.
Program Evaluation of the radKIDS® Youth Personal Empowerment Safety Education Program
Authors: Johnson-Shelton Deborah , Daley Stephen M. , Gau Jeff , Canavan Naomi , Kress Victoria E. 
Published: March 2024

AbstractDeveloping sound evidence of program effectiveness can be difficult for many programs initiated by schools and communities, and impedes many beneficial programs from broader dissemination. This paper shares results of an evaluation approach used with a bullying and victimization prevention program with elementary school children called the radKIDS® Personal Empowerment and Safety Education Program. The purpose of this study was to examine indicators of initial effectiveness of the radKIDS® program for elementary school child safety skill development and instructor training to reduce child victimization and associated trauma and empower healthy psychosocial child development. The study involved 330 active radKIDS® instructors surveyed during two separate two-week periods, resulting in 148 completed questionnaires (45%). Instructors rated their perceptions of what children effectively learned in radKIDS®, the effectiveness of instructor training, and on Social Emotional Learning (SEL) competencies addressed in the program. Evaluation findings confirmed the theoretical model of the program, and that the developmental safety domains impacting children in radKIDS® differs from those in other bullying prevention interventions focused on SEL and other competencies. Recommended areas of improvement for the program included making training less time consuming and more flexible in delivery, provide more practice opportunities and time on skill acquisition during training, and increase supervision and guidance during program implementation.
Erfahrungen mit arbeitsphysiologischen Untersuchungen unter Bedingungen der COVID-19-Pandemie
Authors: Steinhilber Benjamin , Thielmann Beatrice , Böckelmann Irina , Klussmann André , Rieger Monika A. , Liebers Falk 
Published: March 2024

ZusammenfassungWährend der COVID-19-Pandemie kam es zu weitreichenden Einschränkungen in der arbeitsphysiologischen Forschung. Laufende Studien wurden eingestellt oder konnten nur unter strengen Hygienemaßnahmen fortgeführt werden. Dies gefährdete sowohl die Qualität der Forschungsergebnisse als auch damit verbundene akademische Qualifikationsarbeiten. Im vorliegenden Artikel werden daher die Erfahrungen von Wissenschaftler*innen aus vier wissenschaftlichen Einrichtungen zur Umsetzung arbeitsphysiologischer Forschung und Lehre während der Pandemie geschildert, die unter verschiedenen gesellschaftlichen, institutionellen und infrastrukturellen Rahmenbedingungen abliefen. Die Autorengruppe hat auf dieser Basis eine Checkliste erarbeitet, mit der eine Gefährdungsbeurteilung für die Durchführung arbeitsphysiologischer Labor- und Feldforschung unter erhöhtem infektiösem Gefährdungspotenzial, wie z. B. während einer erneuten Pandemie- oder Grippewelle, durchgeführt werden kann. In der Zusammenführung der Erfahrungen zeigte sich, dass die entwickelten Arbeitsschutzkonzepte ständig überprüft und gemäß gesetzlichen Vorgaben, der Infektionslage sowie des Impfstatus innerhalb der Bevölkerung angepasst werden müssen. Auch die Schulung der Studienteams zur richtigen Anwendung der eingesetzten Schutzmaßnahmen wurde als wichtig erachtet, ebenso wie die Kommunikation mit den Studienteilnehmenden zu den ergriffenen Schutzmaßnahmen. Darüber hinaus ist es empfehlenswert, das Arbeitsschutzkonzept (inkl. Hygienekonzept) mit der beratenden Ethikkommission und dem Betriebsärztlichen Dienst der jeweiligen Forschungseinrichtung abzustimmen. In der Checkliste selbst werden die wesentlichen Gefährdungen mit passenden Schutzmaßnahmen beschrieben, so dass Gefährdungen erkannt und angemessene Maßnahmen abgeleitet werden können. Obwohl an den vier Standorten keine SARS-CoV-2-Infektionen aufgrund der Forschungsaktivitäten bekannt wurden, muss eingeräumt werden, dass die Wirksamkeit der eingesetzten Maßnahmen nicht aktiv überprüft wurde. Dennoch legen aktuelle Studien zur Wirksamkeit unterschiedlicher Schutzmaßnahmen nahe, dass die entwickelte Checkliste wichtige und wirkungsvolle Maßnahmen enthält. Eine Wichtung der Maßnahmen wurde nicht vorgenommen, jedoch wurden sie entsprechend dem T‑O-P-Prinzip charakterisiert.
A multi-intent-aware recommendation algorithm based on interactive graph convolutional networks
Authors: Zhang Junsan , Gao Hui , Xiao Sen , Zhu Jie , Wang Jian 
Published: March 2024

AbstractIn recent years, graph neural networks (GNNs) have been widely applied in recommender systems. However, existing recommendation algorithms based on GNNs still face challenges in node aggregation and feature extraction processes because they often lack the ability to capture the interactions between users and items, as well as users’ multiple intentions. This hinders accurate understanding of users’ needs. To address the aforementioned issues, we propose a recommendation model called multi-intent-aware interactive graph convolutional network (Multi-IAIGCN). This model is capable of integrating multiple user intents and adopts an interactive convolution approach to better capture the information on the interaction between users and items. First, before the interaction between users and items begins, user intents are divided and mapped into a graph. Next, interactive convolutions are applied to the user and item trees. Finally, by aggregating different features of user intents, predictions of user preferences are made. Extensive experiments on three publicly available datasets demonstrate that Multi-IAIGCN outperforms existing state-of-the-art methods or can achieve results comparable to those of existing state-of-the-art methods in terms of recall and NDCG, thus verifying the effectiveness of Multi-IAIGCN.
IgA Nephropathy and Remitting Seronegative Symmetrical Synovitis with Pitting Edema (RS3PE): A Case Report
Authors: Damas Juliana , Marouço Catarina , Barata Rui , Pereira Tiago Assis , Fonseca Nuno Moreira , Navarro David , Góis Mário , Viana Helena , Sousa João , Gruner Heidi , Jorge Cristina 
Published: March 2024

Abstract
IgA nephropathy (IgAN) remains the most frequent glomerular disease worldwide, with a broad spectrum of clinical and histological presentations. It has been associated with many secondary causes. The remitting seronegative symmetrical synovitis with pitting edema (RS3PE) syndrome is an autoimmune disorder characterized by swelling in the extremities and negative autoimmune serological tests. The primary treatment for this condition involves the use of immunosuppressive therapy. Although several triggers have been identified, the exact cause of this condition is still unknown. We report a case of a 53-year-old man who presented with acute exacerbation of chronic kidney disease, whose etiological study revealed advanced IgAN, associated with pleural and pericardial effusions. Even with volume optimization and dialysis intensification, the pericardial effusion worsened, despite the resolving pleural effusion. Upper arm arthralgias were developed afterward. An extensive study ruled out other causes and the hypothesis of RS3PE syndrome was considered. Glucocorticoid (GC) therapy was instituted for 6 months with clinical improvement and no recurrence at 2 years follow-up. The complexity of this case shows the importance of considering a wider diagnosis for the complaints of arthralgias and volume overload, reinforcing the importance of clinical awareness for other concurrent conditions, whose treatment may be lifesaving.
Building a Competency Framework to Integrate Inter-disciplinary Precision Medicine Capabilities into the Medical Technology and Pharmaceutical Industry
Authors: Conway Nicholette , Chisholm Orin 
Published: March 2024

Abstract
Introduction
Integration of precision medicine (PM) competencies across the Medical Technology and Pharmaceutical industry is critical to enable industry professionals to understand and develop the skills needed to navigate the opportunities arising from rapid scientific and technological innovation in PM. Our objective was to identify the key competency domains required by industry professionals to enable them to upskill themselves in PM-related aspects of their roles.

Methods
A desktop research review of current literature, curriculum, and healthcare trends identified a core set of domains and subdomains related to PM competencies that were consistent across multiple disciplines and competency frameworks. A survey was used to confirm the applicability of these domains to the cross-functional and multi-disciplinary work practices of industry professionals. Companies were requested to trial the domains to determine their relevance in practice and feedback was obtained.

Results
Four PM-relevant domains were identified from the literature review: medical science and technology; translational and clinical application; governance and regulation and professional practice. Survey results refined these domains, and case studies within companies confirmed the potential for this framework to be used as an adjunct to current role specific competency frameworks to provide a specific focus on needed PM capabilities.

Conclusion
The framework was well accepted by local industry as a supplement to role specific competency frameworks to provide a structure on how to integrate new and evolving technologies into their current workforce development planning and build a continuous learning and cross-disciplinary mindset.