bluuebunny/crossref_metadata_2025_split huggingface dataset:
Skin‐Inspired All‐Natural Biogel for Bioadhesive Interface
Authors: Lan Lingyi , Ping Jianfeng , Li Huiyan , Wang Chengjun , Li Guang , Song Jizhou , Ying Yibin 
Published: April 2024

AbstractNatural material‐based hydrogels are considered ideal candidates for constructing robust bio‐interfaces due to their environmentally sustainable nature and biocompatibility. However, these hydrogels often encounter limitations such as weak mechanical strength, low water resistance, and poor ionic conductivity. Here, inspired by the role of natural moisturizing factor (NMF) in skin, a straightforward yet versatile strategy is proposed for fabricating all‐natural ionic biogels that exhibit high resilience, ionic conductivity, resistance to dehydration, and complete degradability, without necessitating any chemical modification. A well‐balanced combination of gelatin and sodium pyrrolidone carboxylic acid (an NMF compound) gives rise to a significant enhancement in the mechanical strength, ionic conductivity, and water retention capacity of the biogel compared to pure gelatin hydrogel. The biogel manifests temperature‐controlled reversible fluid‐gel transition properties attributed to the triple‐helix junctions of gelatin, which enables in situ gelation on diverse substrates, thereby ensuring conformal contact and dynamic compliance with curved surfaces. Due to its salutary properties, the biogel can serve as an effective and biocompatible interface for high‐quality and long‐term electrophysiological signal recording. These findings provide a general and scalable approach for designing natural material‐based hydrogels with tailored functionalities to meet diverse application needs.
Far‐reaching blues: Long‐distance migration of the invasive Atlantic blue crab
Authors: Bedmar Sergio , Oficialdegui Francisco J. , Clavero Miguel 
Published: April 2024

Abstract
Upstream migration of the Atlantic blue crab Callinectes sapidus is well described in its native range, but it is little known in invaded areas.
Here, we report several long‐distance migration events of the blue crab in the Iberian Peninsula and use a global database to calculate the probability of occurrence of the species in relation to distance to sea. We then exemplify the potential of blue crab impacts on freshwaters by overlapping its probability of occurrence with that of the critically endangered European eel Anguilla anguilla. Finally, we evaluate the extent to which dam barriers can halt the upstream migration of the blue crab.
Invasive blue crab has been detected at 108 km from the sea in the Guadalquivir River (the farthest distance reported in the non‐native range), at 71 km in the Guadiana River and at 53 km in the Ebro River. The probability of occurrence decreased steeply in the first upstream kilometres, but it is still concerning at a dozen kilometres from the river mouth (50% at 19 km, 25% at 38 km, and 3% at 100 km). The blue crab invasive potential widely overlaps (63%) with the Iberian range of the European eel. The blocking effect of dams on the potential invasion of freshwater systems by the blue crab was limited (13%).
Our study highlights the need to study the upstream migration of the blue crab within its non‐native range, since it could involve serious impacts in reachable river and stream habitats.
Marine biodiversity conservation: The cultural aspect of marine protected areas in Ghana
Authors: Karakara Alhassan Abdul‐Wakeel , Peprah James A. , Dasmani Isaac 
Published: April 2024

Abstract

Studying fishers and fishing communities' social‐cultural structures is vital in policy‐making concerning local marine ecosystem sustainability. Previous studies on marine communities seldom neglected the role of culture in marine biodiversity conservation, especially a marine protected area (MPA) establishment.
This study first explores the cultural practices in coastal communities in Ghana that have the potential for the conservation of the marine ecosystem (MPA); second, it examines the willingness of coastal communities to welcome an MPA establishment.
Primary data were collected using focus group discussions with 9 fishermen, key informant interviews with 20 chief fishermen, and self‐administered questionnaires to 491 fishermen across 9 semi‐urban, 2 urban, and 16 villages along the coast of Ghana.
Adopting the convergent parallel mixed‐methods research design (quantitative method includes descriptive analysis using tables, charts, diagrams, and χ2 bivariate analysis; and qualitative method involves a narrative format), the study underscored that the socioeconomic characteristics of fishermen are diverse and mixed. Most of the fishermen do not know what an MPA is but are willing to accept an MPA initiative. Certain cultural practices such as the prohibition of gathering certain species, traditional close season, and fishing holidays are found to be conducive to an MPA initiative.
These cultural practices should be integrated into an MPA policy. Fisheries practitioners should consider an ecosystem‐based approach (including cultural values) to fisheries management and fishermen should endeavour to learn new skills outside the industry.
Outcomes and considerations for retrograde intrarenal surgery (RIRS) in the setting of multiple and large renal stones (>15 mm) in children: Findings from multicentre and real‐world setting
Authors: Juliebø‐Jones Patrick , Gauhar Vineet , Lim Ee Jean , Traxer Olivier , Madarriaga Yesica Quiroz , Castellani Daniele , Fong Khi Yung , Bujons Anna , Ragoori Deepak , Shrestha Anil , Vaddi Chandra Mohan , Bhatia Tanuj Paul , Sekerci Cagri Akin , Tanidir Yiloren , Teoh Jeremy Yuen‐Chun , Somani Bhaskar Kumar 
Published: April 2024

AbstractPurposeThe aim of this study is to evaluate the outcomes of retrograde intra renal surgery (RIRS) in the setting of large or multiple stones in children (<18 years).Materials and MethodsRetrospective analysis was performed of paediatric RIRS cases at nine centres worldwide over a 6‐year period. Patients were divided into two groups: Group 1 had a single stone <15 mm. Group 2 had either multiple stones, maximum stone diameter of >15 mm, or both. Outcomes included stone free rate (SFR) and complications within 30 days.ResultsIn total, 344 patients were included with 197 and 147 in Groups 1 and 2, respectively. Ureteric access sheaths were more frequently used in Group 2 (39.5% vs. 56.8%, p = 0.021). The operation time was significantly longer in Group 2 (p < 0.001). SFR after a single procedure was 84.7% in Group 1 and 63.7% in Group 2. Overall complication rates in Groups 1 and 2 were 7.6% and 33.3%, respectively. The most frequently reported complication in both groups was post‐operative fever (4.4% vs. 14%, p = 0.004). The rate of Clavien I/II complications in groups 1 and 2 was 6% and 25.1%, respectively (p < 0.05). The rate of Clavien ≥ III complications in groups 1 and 2 was 1.6% and 8.1%, respectively (p < 0.05). On multivariate analysis, total operation time, stone size and multiplicity were significant predictors of residual fragments.ConclusionsRIRS can be performed in paediatric cases with large and multiple stone burdens, but the complication rate is significantly higher when compared to smaller stones.
Solvent Effects on Heterogeneous Catalysis for the Selective Hydrogenation
Authors: Li Jinlei , Xi Yongjie , Qiao Yan , Zhao Zelun , Liu Jianhua , Li Fuwei 
Published: April 2024

AbstractSolvent effects add a new dimension for tuning the activity and selectivity of heterogeneous catalytic reactions, which is extensively employed in the hydrogenation of unsaturated compounds with multiple functional groups. In this concept, we briefly summarize recent developments on how the solvent effects affect the catalytic performance from the following aspects: 1) the polarity of the solvent can influence the interaction between the solvent and the reactant or intermediate; 2) the composition of mixed solvent can influence the reactivity of the reactant or intermediate; 3) solvent effect varies with the metal identity and support; 4) the solvent can induce surface modification of the supported catalysts. This summarization will provide insights into the rational development of efficient and selective heterogeneous hydrogenation catalytic system to realize the precise synthesis of desired chemicals.
Unveiling a novel cellular stress response mechanism to photodamage
Authors: Dutta Naibedya , Garcia Gilberto , Higuchi‐Sanabria Ryo 
Published: April 2024

AbstractUltraviolet (UV) radiation, a component of sunlight, holds both advantageous anddetrimental effects on human health. While shorter wavelengths of UV radiationaid in melanin and vitamin D synthesis, longer wavelengths pose risks like skincancer and premature aging due to DNA damage. To combat such stress, cellsemploy various mechanisms, including the heat shock response (HSR). Activation of this response involves a highly regulated transcriptional processorchestrated by heat shock factors (HSFs). While HSF1 has been observed as a keytranscription factor for HSR, other HSFs are also found to be associated withdiverse cellular functions, including stress responses. Here, we discuss arecent study by Feng et al., published in Clinical and Translational Medicine, shedding light on the novel function of HSF4 in regulating inflammation and senescence following UV exposure. The researchers observed acomplex of HSF4 and the cofactor COIL (Coilin) at R‐loops–aberrant DNA‐RNAhybrid structures arising from UV‐induced DNA damage in human skin cells. Inthe study, they proposed the HSF4‐COIL complex at R‐loops as a potential therapeutic target to mitigate UV‐induced skin damage.
Cross‐scale analysis reveals interacting predictors of annual and perennial cover in Northern Great Basin rangelands
Authors: Case Madelon F. , Davies Kirk W. , Boyd Chad S. , Aoyama Lina , Merson Joanna , Penkauskas Calvin , Hallett Lauren M. 
Published: April 2024

AbstractExotic annual grass invasion is a widespread threat to the integrity of sagebrush ecosystems in Western North America. Although many predictors of annual grass prevalence and native perennial vegetation have been identified, there remains substantial uncertainty about how regional‐scale and local‐scale predictors interact to determine vegetation heterogeneity, and how associations between vegetation and cattle grazing vary with environmental context. Here, we conducted a regionally extensive, one‐season field survey across burned and unburned, grazed, public lands in Oregon and Idaho, with plots stratified by aspect and distance to water within pastures to capture variation in environmental context and grazing intensity. We analyzed regional‐scale and local‐scale patterns of annual grass, perennial grass, and shrub cover, and examined to what extent plot‐level variation was contingent on pasture‐level predictions of site favorability. Annual grasses were widespread at burned and unburned sites alike, contrary to assumptions of annual grasses depending on fire, and more common at lower elevations and higher temperatures regionally, as well as on warmer slopes locally. Pasture‐level grazing pressure interacted with temperature such that annual grass cover was associated positively with grazing pressure at higher temperatures but associated negatively with grazing pressure at lower temperatures. This suggests that pasture‐level temperature and grazing relationships with annual grass abundance are complex and context dependent, although the causality of this relationship deserves further examination. At the plot‐level within pastures, annual grass cover did not vary with grazing metrics, but perennial cover did; perennial grasses, for example, had lower cover closer to water sources, but higher cover at higher dung counts within a pasture, suggesting contrasting interpretations of these two grazing proxies. Importantly for predictions of ecosystem response to temperature change, we found that pasture‐level and plot‐level favorability interacted: perennial grasses had a higher plot‐level cover on cooler slopes, and this difference across topography was starkest in pastures that were less favorable for perennial grasses regionally. Understanding the mechanisms behind cross‐scale interactions and contingent responses of vegetation to grazing in these increasingly invaded ecosystems will be critical to land management in a changing world.
Quality‐related descriptors to increase fresh blueberries purchase—Evidence from a basket‐based choice experiment
Authors: Ma Xueying , Gallardo R. Karina , Canales Elizabeth , Iorizzo Massimo 
Published: April 2024

AbstractThis study addresses the need to boost fruit and vegetable consumption amidst rising diet‐related health concerns. Blueberries, rich in phenolic phytochemicals, offer significant health benefits. Using a basket‐based choice experiment (BBCE), the study identifies sensory descriptors that enhance blueberry purchasing likelihood. Packaging with a “Stay Fresh” label reduces price sensitivity compared to others. Additionally, blueberries are commonly purchased alongside other berries rather than as substitutes. Demographic factors such as gender, age, education, employment, fitness, ethnicity, region, nutritional value perception, and budget influence blueberry selection. These insights can aid growers, retailers, and marketers in increasing fresh blueberry demand.
Biventricular Impairment and Ventricular Interdependence in Patients With Alcoholic Cardiomyopathy: Insights Through Cardiac Magnetic Resonance Imaging
Authors: Wang Jin , Yang Zhi‐Gang , Fang Han , Yan Wei‐Feng , Shen Meng‐Ting , Guo Ying‐Kun , Jiang Li , Jiang Yu , Min Chen‐Yan , Li Yuan 
Published: April 2024

BackgroundAlcoholic cardiomyopathy (ACM) can lead to progressive cardiac dysfunction and heart failure, but little is known about biventricular impairment and ventricular interdependence (VI) in ACM patients.PurposeTo use cardiac MRI to investigate biventricular impairment and VI in ACM patients.Study TypeRetrospective.PopulationForty‐one male patients with ACM and 45 sex‐ and age‐matched controls.Field Strength/Sequence3.0 T/balanced steady‐state free precession sequence, inversion recovery prepared echo‐planar imaging sequence and phase‐sensitive inversion recovery sequence.AssessmentBiventricular structure, function, and global strain (encompassing peak strain [PS], peak systolic, and diastolic strain rate), PS of interventricular septal (IVS), microvascular perfusion (including upslope and time to maximum signal intensity [TTM]), late gadolinium enhancement (LGE), and baseline characteristics were compared between the controls and ACM patients.Statistical TestsStudent's t‐test, Mann–Whitney U test, Pearson's correlation, and multivariable linear regression models with a stepwise selection procedure. A two‐tailed P value <0.05 was deemed as statistically significant.ResultsCompared to control subjects, ACM patients showed significantly biventricular adverse remodeling, reduced left ventricle (LV) global upslope and prolonged global TTM, and the presence of LGE. ACM patients were characterized by a significant decline in all global strain within the LV, right ventricle (RV), and IVS compared with the controls. RV global PS was significantly associated with LV global PS and IVS PS in radial, circumferential, and longitudinal directions. Multivariable analyses demonstrated the longitudinal PS of IVS was significantly correlated with RV global radial PS (β = 0.614) and circumferential PS (β = 0.545). Additionally, RV global longitudinal PS (GLPS) was significantly associated with radial PS of IVS (β = −0.631) and LV GLPS (β = 1.096).Data ConclusionACM patients exhibited biventricular adverse structural alterations and impaired systolic and diastolic function. This cohort also showed reduced LV microvascular perfusion, the presence of LGE, and unfavorable VI.Evidence Level3Technical EfficacyStage 3
Fully Automated Valve Segmentation for Blood Flow Assessment From 4D Flow MRI Including Automated Cardiac Valve Tracking and Transvalvular Velocity Mapping
Authors: in de Braekt Thomas , Aben Jean‐Paul , Maussen Marc , van den Bosch Harrie C.M. , Houthuizen Patrick , Roest Arno A.W. , van den Boogaard Pieter J. , Lamb Hildo J. , Westenberg Jos J.M. 
Published: April 2024

BackgroundAutomated 4D flow MRI valvular flow quantification without time‐consuming manual segmentation might improve workflow.PurposeCompare automated valve segmentation (AS) to manual (MS), and manually corrected automated segmentation (AMS), in corrected atrioventricular septum defect (c‐AVSD) patients and healthy volunteers, for assessing net forward volume (NFV) and regurgitation fraction (RF).Study TypeRetrospective.Population27 c‐AVSD patients (median, 23 years; interquartile range, 16–31 years) and 24 healthy volunteers (25 years; 12.5–36.5 years).Field strength/SequenceWhole‐heart 4D flow MRI and cine steady‐state free precession at 3T.AssessmentAfter automatic valve tracking, valve annuli were segmented on time‐resolved reformatted trans‐valvular velocity images by AS, MS, and AMS. NFV was calculated for all valves, and RF for right and left atrioventricular valves (RAVV and LAVV). NFV variation (standard deviation divided by mean NFV) and NFV differences (NFV difference of a valve vs. mean NFV of other valves) expressed internal NFV consistency.Statistical TestsComparisons between methods were assessed by Wilcoxon signed‐rank tests, and intra/interobserver variability by intraclass correlation coefficients (ICCs). P < 0.05 was considered statistically significant, with multiple testing correction.ResultsAMS mean analysis time was significantly shorter compared with MS (5.3 ± 1.6 minutes vs. 9.1 ± 2.5 minutes). MS NFV variation (6.0%) was significantly smaller compared with AMS (6.3%), and AS (8.2%). Median NFV difference of RAVV, LAVV, PV, and AoV between segmentation methods ranged from −0.7–1.0 mL, −0.5–2.8 mL, −1.1–3.6 mL, and − 3.1–‐2.1 mL, respectively. Median RAVV and LAVV RF, between 7.1%–7.5% and 3.8%–4.3%, respectively, were not significantly different between methods. Intraobserver/interobserver agreement for AMS and MS was strong‐to‐excellent for NFV and RF (ICC ≥0.88).Data ConclusionMS demonstrates strongest internal consistency, followed closely by AMS, and AS. Automated segmentation, with or without manual correction, can be considered for 4D flow MRI valvular flow quantification.Level of Evidence3Technical EfficacyStage 3
Understanding disparities in hidradenitis suppurativa through social and structural determinants of health
Authors: Polaskey Meredith Tyree , Chovatiya Raj 
Published: April 2024

AbstractHidradenitis suppurativa (HS) is a chronic inflammatory skin disorder with a global prevalence and presentation that varies widely and is influenced by both intrinsic and extrinsic factors. While research into disease heterogeneity and burden has traditionally focused on biological and genetic differences (i.e., intrinsic factors), emerging evidence suggests that social determinants of health (SDOH) and structural determinants of health (StDOH) (i.e., extrinsic factors) play a pivotal role in the disparities observed in HS. This narrative review consolidates insights on the influence of SDOH and StDOH on HS incidence, severity, and health disparities. We highlight the importance of SDOH, including economic stability, education quality and access, healthcare quality and access, neighbourhood environment, and social/community context in shaping HS outcomes. Furthermore, we emphasize the overarching role of StDOH, including government processes, economic policies, social/public policies, and cultural and societal values in determining health outcomes. Addressing these determinants is crucial for devising effective interventions and enhancing patient outcomes. Future research should focus on a holistic understanding of HS, moving beyond a purely biological perspective to consider the intricate interplay of social and structural determinants.
Ambulatory knee arthroscopic surgery yields cost savings and improved health outcomes
Authors: Luksameesate Parnnaphat , Watcharopas Ratthapoom , Sangkum Lisa , Saengpetch Nadhaporn , Taychakhoonavudh Suthira 
Published: April 2024

AbstractPurposeThis study measured the health‐related quality of life (HRQoL) and costs and conducted a cost–utility analysis and budget impact analysis of ambulatory knee arthroscopic surgery compared with inpatient knee arthroscopic surgery in Thailand from a societal perspective.MethodsHealth outcomes were measured in units of quality‐adjusted life year (QALY) based on the Thai version of the EQ‐5D‐5L Health Questionnaire, and costs were obtained from an electronic database at a tertiary care hospital (Ramathibodi Hospital). A cost–utility analysis was performed to evaluate ambulatory and inpatient surgery using the societal perspective and a 2‐week time horizon. The incremental cost‐effectiveness ratio was applied to examine the costs and QALYs. One‐way sensitivity analysis was used to investigate the robustness of the model. Budget impact analysis was performed considering over 5 years.ResultsA total of 161 knee arthroscopic patients were included and divided into two groups: ambulatory surgery (58 patients) and inpatient surgery (103 patients). The total cost of the inpatient surgery was 2235 United States dollars (USD), while the ambulatory surgery cost was 2002 USD. The QALYs of inpatient surgery and ambulatory surgery were 0.79 and 0.81, respectively, resulting in the ambulatory surgery becoming a dominant strategy (cost reduction of 233 USD with an increase of 0.02 QALY) over the inpatient surgery. The ambulatory surgery led to net savings of 4.5 million USD over 5 years. Medical supply costs are one of the most influential factors affecting the change in results.ConclusionAmbulatory knee arthroscopic surgery emerged as a cost‐saving strategy over inpatient surgery, driven by lower treatment costs and enhanced HRQoL. Budget impact analysis indicated net savings over 5 years, supporting the feasibility of adopting ambulatory knee arthroscopic surgery. Our findings were advocated for its application across diverse hospitals and informed policymakers to improve reimbursement systems in low‐ to middle‐income countries and Thailand.Level of EvidenceLevel IV.