bluuebunny/crossref_metadata_2025_split huggingface dataset:
Retropharyngeal abscess: a clinical review
Authors: Goldenberg D. , Golz A. , Joachims H. Z. 
Published: November 2007

AbstractRetropharyngeal abscesses are uncommon but potentially lethal infections, especially in the paediatric population under the age of five years. Abscesses in this group are classically secondary to upper respiratory infections especially oropharyngeal infections, while in the adult group they are usually secondary to trauma, foreign bodies, or as a complication of dental infections. Early diagnosis and the wide spread use of antibiotics have made these infections less common today. Between the years 1985–1996,19 cases of retropharyngeal abscesses were treated in our department. Factors such as age, sex, aetiology, presenting signs, symptoms, methods of diagnosis, treatment and complications were reviewed. Thirty-two per cent of the cases were secondary trauma. A lateral neck film showing widening of the prevertebral space was the most important diagnostic tool, computed tomography (CT) scan was used in 63 per cent of cases to verify the signs of an abscess and to provide more accurate anatomical localization.Thirteen cases required surgical drainage. The single most commonly isolated pathogen wasStreptococcus pyogenes. There were no deaths and only one recurrence requiring repeated surgical drainage. One case was complicated by a spinal canal abscess. We also report two cases of retropharyngeal abscess in children caused by swallowing of unusual foreign bodies.
Cyclin D1 protein expression is related to clinical progression in laryngeal squamous cell carcinomas
Authors: Capaccio Pasquale , Pruneri Giancarlo , Carboni Nadia , Pagliari Angelo Virgilio , Buffa Roberto , Neri Antonino , Ottaviani Antonio , Pignataro Lorenzo 
Published: November 2007

AbstractThe expression of cyclin D1 gene was investigated in 74 laryngeal squamous cell carcinomas (LSCCs) in order to determine its clinical and prognostic value. Overexpression of cyclin Dl was detected immunohistochemically using DCS6 monoclonal antibody on formalin-fixed, paraffin-embedded tissue sections. Cyclin D1 expression was detected in 22 of the 74 cases investigated (30 per cent), thirteen of which presented nodal metastases (59 per cent); of the patients without any detectable cyclin D1 protein expression, six presented nodal metastases (12 per cent). Cyclin D1 protein expression was found in five per cent of the specimens of normal mucosa, eight per cent of thosewith low-grade dysplasia and 20 per cent of those with high-grade dysplasia. A statistically significant association was found between cyclin D1 expression and the supraglottic site (p<0.05), tumour extension (p<0.001), the presence of lymph node metastases (p<0.001), and advanced clinical stage (p<0.001). Cyclin D2 expression analysis is an important tool in the selection of LSCC patients with an aggressive clinical course.
Endoscopic laser myotomy in the treatment of pharyngeal diverticula
Authors: Bradwell R. A. , Bieger A. K. , Strachan D. R. , Homer J. J. 
Published: November 2007

AbstractThe endoscopic approach is a simple and cost-effective option in the treatment of hypopharyngeal diverticula. Whereas almost a third of all endoscopic myotomies performed by UK otolaryngologists are carried out with the stapling technique, CO2 laser diverticulotomy has not been given as much consideration (Koay et al., in press).We report on the first British series of 15 patients treated between 1985 and 1993 with microscopic laser diverticulotomy. The follow-up period was four to 11 years. Complications occurred in three patients, two patients required a repeat myotomy and 11 patients have been satisfied with their swallow since the operation.Our results are similar to those of larger studies. The laser technique is more established than the stapling gun myotomy and it has the advantage of superior visualization. It may also be used in small pouches which do not admit the insertion of a stapling gun.
Long-term observation of subcutaneous tissue reaction to synthetic auditory ossicle (Apaceram®) in rats
Authors: Li Dong-Jun , Ohsaki Katsuichiro , Ii Kunio , Ye Qing , Nobuto Yoko , Tenshin Satoru , Takano-Yamamoto Teruko 
Published: November 2007

AbstractThe present study evaluates histological characteristics of the soft tissue response to long-term implantation of Apaceram™ discs composed of dense hydroxyapatite in rats. Discs were implanted into the subcutaneous tissue of 76 rats for six to 20 months. Decalcified histological sections stained with haematoxylin and eosin (H & E) and Mallory's azan were examined. Different cell types surrounding implants were counted. The greatest proportion of macrophages was found at six months (13.5 per cent). This proportion gradually decreased to four per cent at 20 months. Small numbers of lymphocytes and foreign body giant cells were observed in every group, but neither neutrophils nor osteogenesis were observed in any specimens. Results of the present study and previous related studies indicate that despite reappearance of a small number of macrophages six months after implantation, Apaceram™ is useful for reconstructive surgery.
Temporalis fascia grafts shrink
Authors: England R. J. , Strachan D. R. , Buckley J. G. 
Published: November 2007

AbstractTemporalis fascia, placed as an underlay graft, is commonly used to repair tympanic membrane perforations. Graft failure, however, is a well recognized complication. Grafts are often allowed to dry out during the procedure and, therefore, are often positioned in a dry or partially dehydrated state and only become fully rehydrated after placement. This study looked at how the size of the temporalis fascia alters with its state of hydration. The size of 20 temporalis fascia grafts was measured when fresh, after flattening and allowing them to dry, and finally after rehydrating the grafts with 0.9 per cent saline solution. Significant shrinkage was demonstrated. It is therefore proposed that a cause of increased failure rates, particularly in anterior myringoplasties, is loss of underlay due to graft rehydration and shrinkage. Thus graft shrinkage should be considered when positioning the graft.
Intra-operative facial nerve monitoring. Its predictive value after skull base surgery
Authors: Magliulo Giuseppe , Zardo Francesco 
Published: November 2007

AbstractPurposeFacial nerve monitoring can be used to predict post-operative facial function after skull base surgery. In this study three methods of prediction of facial function were compared. These methods utilize various parameters of the evoked electromyographic monitoring.Material and methodsTwenty-three patients who underwent surgery for skull base diseases were retrospectively reviewed. Amplitude of ongoing electromyographic activity, stimulation current thresholds and amplitude of evoked response were analysed. The predictive value of the three methods was correlated with post-operative facial nerve function.ResultsThe method that used only the stimulation thresholds predicted the final post-operative facial function in 86.9 per cent of the patients. The second employed a mathematical ratio which combined the amplitude of evoked response and the stimulation current thresholds and confirmed the prediction of the facial function in 91.3 per cent of the patients. The last method does not consider the stimulation thresholds greater than 0.05 mA and failed to predict the final VIIth nerve function in patients in whom the stimulation was greater than 0.05 mA.ConclusionAnalysis of prognostic value demonstrates that the first two methods had the smaller degree of variation showing the better sensitivity.
An unique tumour of the geniohyoid muscle: an intramuscular haemangioma
Authors: Harar R. P. S. , Kalan A. , Brown C. L. , Kenyon G. S. 
Published: November 2007

AbstractWe present the first case report in the English literature of an intramuscular haemangioma of the geniohyoid muscle. This occurred in a 24-year-old female and the diagnosis was not made prior to resection. Haemangiomas are uncommon tumours of the head and neck and intramuscular haemangiomas account for fewer than one per cent of the total. Diagnosis of the vascular nature of the tumour is often missed. Recurrence is common and usually due to incomplete excision. A review of the literature and a case report of theselocally destructive lesions is presented.
Horizontal glottectomy: functional and oncological results
Authors: Carrat Xavier , Francois Jean-Marc , Devars François , Carles Dominique , Traissac Louis 
Published: November 2007

AbstractThe authors report on their experience with 25 cases of horizontal glottectomy and discuss the functional and oncological results of this operation. Indications for this procedure are Tia and Tib glottic carcinomas. The overall three-year and five-year survival was respectively 94 and 88 per cent. Distant metastasis appears to be the major long-term failure, three patients dying of lung carcinoma. Short functional rehabilitation was observed in all cases. Decannulation was achieved in 100 per cent of the cases and none of our patients had laryngeal stenosis. The average time of removal of the nasogastric tube was 11.8 days. Because of its high local control and reduced functional after effects, horizontal glottectomy appears to be a reliable and safe procedure for limited glottic carcinomas and must be included in their therapeutic management.
‘Farmer's ear’: sudden sensorineural hearing loss due toChlamydia psittaciinfection
Authors: Brewis C. , McFerran D. J. 
Published: November 2007

AbstractA case of sudden sensorineural hearing loss in association with aChlamydia psittacipneumonia is reported. Rapid recovery was seen when the patient was treated with high dose steroids and appropriate antibiotics. This is the first such case report in the literature.
Chondroid syringoma of the nose: report of a case
Authors: Bhargava Deepa , Bhusnurmath Shivayogi , Daar A. S. 
Published: November 2007

AbstractChondroid syringoma or mixed tumour of the skin is a rare benign tumour which can present on the face. We present here the case of a patient who underwent an excisional biopsy of a small painless nodule in the soft triangle of the nose for cosmetic reasons. The clinical presentation, histology and treatment, with review of the relevant literature, is discussed.
Ortner's syndrome: a centenary review of unilateral recurrent laryngeal nerve palsy secondary to cardiothoracic disease
Authors: Thirlwall Andrea Simone 
Published: November 2007

AbstractOrtner's Syndrome (described 100 years ago in 1897) is a clinical entity with hoarseness due to a left recurrent laryngeal nerve (LRLN) palsy caused by cardiac disease. A 35-year-old woman presented with a LRLN palsy due to a huge thoracic aneurysm. The anatomy of the LRLN and the cardiothoracic complaints which may cause the palsy are discussed.
Four cases of aggressive MRSA wound infection following head and neck surgery
Authors: Parton M. , Beasley N. J. P. , Harvey G. , Houghton D. , Jones A.S. 
Published: November 2007

AbstractFour cases of serious MRSA wound infection following head and neck surgery have been identified. One patient died. At post mortem a mediastinal abscess containing MRSA was found to have eroded into the innominate artery causing fatal haemorrhage. The other three suffered serious wound infections, two requiring further surgery. Once MRSA hadbeen identified they were treated with intravenous teicoplanin and all made a full recovery.
Temporal bone pathology of acoustic neuroma correlating with presence of electrocochleography and absence of auditory brainstem response
Authors: Kaga Kimitaka , Iwasaki Shinichi , Tamura Akira , Suzuki Jun-Ichi , Haebara Hideyuki 
Published: November 2007

AbstractThe temporal bone pathology of a 74-year-old female affected by vestibular schwannoma was compared with findings of auditory brainstem response and electrocochleography. At age 71, she complained of hearing loss in the left ear in which pure tone audiometry revealed threshold elevation in the middle- and high-frequency range. Temporal bone CT scanning revealed a medium-sized cerebellopontine angle tumour in the left ear. ABR showed no response in the left ear, but the electrocochleography showed clear compound action potentials. Three years later, at age 74, she died of metastatic lung cancer and sepsis. The left temporal bone pathology consisted primarily of a large vestibular schwannoma occupying the internal auditory meatus. The organ of Corti was well preserved in each turn. In the modiolus, the numbers of spiral ganglion cells and cochlear nerve fibres in each turn were decreased. These histological findings suggest that clear compound action potentials were recorded from the distal portion of the cochlear nerve in spite of the presence of the vestibular schwannoma, but ABR could not be detected because of the blockade of the proximal portion of the cochlear nerve by the vestibular schwannoma.
Laryngeal malakoplakia
Authors: Gupta A. K. , Mann S. B. S. , Singh K. B. , Joshi K. , Sajeeda S. , Kakkar Nandita 
Published: November 2007

AbstractWe report a case of malakoplakia of the epiglottis in a 45-year-old female patient. Only three cases of laryngeal malakoplakia have been reported in the world literature, one of which was associated with tracheal malakoplakia. To our knowledge this is the first reported case of isolated malakoplakia of the epiglottis. Malakoplakia, a rare granulomatous lesion, has been seen more frequently in the urinary tract. Other organs like the genito-urinary tract, testis, epididymis, lymph nodes, middle ear, nasopharynx, tonsil and retroperitoneal tissue have been also involved though less frequently.
Actinomycosis oto-mastoiditis
Authors: Ajal M. , Turner J. , Fagan Paul , Walker Paul 
Published: November 2007

AbstractActinomycosis of the temporal bone is uncommon. There have only been 24 cases previously reported in the English literature. The responsible organism is Actinomyces israelii, an anaerobic filamentous Gram positive bacterium. While the cervico-facial region is the most common site of the disease, involvement of the temporal bone is rare. The diagnosis can sometimes be made clinically by identification of sulphur granules in a glue-like substrate but in all cases involving the temporal bone, the diagnosis has been made at histopathology. Effective therapy consists of surgery followed by the long-term administration of penicillin.
Treatment of chronic otitis externa by KTP/532 laser
Authors: Kumar B. N. , Walsh R. M. , Courteney-Harris R. G. , Wilson P. S. 
Published: November 2007

AbstractThe traditional meatoplasty operations performed for chronic otitis externa, which has entered the ‘fibrotic’ phase, are often unsatisfactory because the results in terms of canal patency, hearing gain and patient satisfaction are variable. Although the use of laser in chronic ear surgery is well recognized, it has not been previously reported as a meatoplasty technique. Ten KTP laser meatoplasty operations were performed on eight patients with chronic otitis externa. This pilot study shows the technique to be effective, fast and with a high patient satisfaction rate in the short-term (mean follow-up period 9.3 months). The average increase in hearing thresholds was 24 dB HL. Significant patient benefit was obtained in at least six out of eight patients using the Belfast rule of thumb. The technique has many advantages over the traditional meatoplasty operations but the long-term results require evaluation.
Merkel cell carcinoma of the pinna
Authors: Skia B. , Bibas A. , Hickey S. A. , Ryley N. G. 
Published: November 2007

AbstractMerkel cell carcinoma is an increasingly recognized tumou r of the skin. The commonest presentation is the head and neck region. Only three cases of this rare tumour have been reporte d on the pinna. A further such case is presented here.
Metastatic follicular thyroid carcinoma to the maxilla
Authors: Hefer Tsila , Manor Ronen , Joachims Henry Zvi , Groisman Gabriel M. , Peled Micha , Gov-Ari Eliav , Laufer Dov 
Published: November 2007

AbstractWe present a unique case of metastatic follicular thyroid carcinoma to the hard palate and the maxillary sinus, a case that to our knowledge has not been reported before. Various malignant tumours that metastize to the maxilla are reviewed, and the therapeutic approach to follicular thyroid carcinoma metastasis to that area is also discussed. Follicular thyroid carcinoma should be included in the list of tumours that metastasize to the maxilla.
Chondrolipoma of the nasopharynx
Authors: Hong Ki Hwan , Seo Soo Yung , Geun Lee Dong 
Published: November 2007

AbstractLipoma is the commonest soft-tissue tumour arising anywhere in the body, but its occurrence in the nasopharynx is extremely rare. Only four cases in adults have been previously reported in the English literature. We describe a 63-year-old woman with a nasopharyngeal mass that was removed transorally and verified histopathologically as chondrolipoma, that is a lipoma with chondroid metaplasia.
Primary lingual tuberculosis: a case report
Authors: Gupta Abhay , Shinde K. J. , Bhardwaj Ira 
Published: November 2007

AbstractTuberculosis is very common in India and Southeast Asia, where the prevalence rate is about four per 1000 population and the incidence rate of the disease is two per cent. Fifteen per cent of the tuberculous population of the world reside in India. Both secondary and primary tuberculous lesions of the tongue and oral cavity are rare. We report a 60-year-old male with the seventh case of primary lingual tuberculosis.
Transverse sinus thrombosis and venous infarction of the brain following unilateral radical neck dissection
Authors: Mahasin Z. Z. , Saleem M. , Gangopadhyay K. 
Published: November 2007

AbstractRadical neck dissection is one of the commonest procedures performed in any unit dealing with head and neck surgery. Intracranial complications following this procedure are uncommon. Transverse sinus thrombosis and venous infarction of the brain following unilateral radical neck dissection have not been reported in the literature. We present a case in which this complication occurred following an uneventful radical neck dissection.
Necrotizing external otitis caused byAspergillus fumigatus: computed tomography and high resolution magnetic resonance imaging in an AIDS patient
Authors: Muñoz Alberto , Martínez-Chamorro Elena 
Published: November 2007

abstractMost necrotizing (malignant) external otitis (NEO) occurs in diabetic patients and is commonly caused byPseudomonas aeruginosa. We report an acquired immunodeficiency syndrome (AIDS) patient with NEO caused byAspergillus fumigatusin which computed tomography (CT) showed destructive petrous bone involvement and magnetic resonance imaging (MRI) of the ear discovered extensive soft tissue and facial nerve involvement. Dedicated MRI studies of the ear in this type of pathology provide new insights relating to nerve dysfunction, that cannot be obtained with CT.
A randomized prospective trial to compare four different ear packs following permeatal middle ear surgery
Authors: Zeitoun H. , Sandhu G. S. , Kuo M. , Macnamara M. 
Published: November 2007

AbstractSurgeons choice of an ear pack is dictated by availability, previous training and personal preference. There has been no recent prospective study evaluating the use of different types of ear packs. This randomized prospective study compares the use of BIPP impregnated ribbon gauze (Aurum), Pope wicks (Xomed-Teace), silastic sheeting (Dow Corning) and tri-adcortyl ointment (Squibb) as an ear dressing following ‘clear’ middle ear procedures via a permeatal approach. The results showed that there was no statistically significant difference in post-operative pain and discomfort experienced, neither was there any significant difference regarding the otolaryngologist's assessment of the degree of canal granulation, stenosis or discharge with the above named packs. This study concludes that non-traditional dressings such as tri-adcortyl ointment or simply a thin silastic sheet placed on the drum are no worse than time honoured BIPP. They have, as well, the advantage of being well-tolerated by the patients.
Primary extramedullary plasmacytoma of the parotid gland: a case report and review of the literature
Authors: Gonzalez-Garcia J. , Ghufoor K. , Sandhu G. , Thorpe P. A. , Hadley J. 
Published: November 2007

AbstractSolitary extramedullary plasmacytomas are uncommon malignant neoplasms with a great predilection for the upper respiratory tract. Extramedullary plasmacytoma involving the parotid gland is an extremely rare condition. This report describes the case of a primary extramedullary plasmacytoma arising in the right parotid gland of a 63-year-old man. A review of the literature reveals that this disease has generally a good prognosis, provided that multiple myeloma has been excluded. The treatment of choice should be surgical excision followed by radiotherapy, although from this study there is insufficient evidence to suggest that this is more effective than surgery alone. All patients must have regular long-term follow-up to monitor for recurrence or dissemination, in which event chemotherapy may be considered in addition to the other treatment modalities.
Giant aneurysm of the petrous internal carotid artery: diagnosis and treatment
Authors: Coley S. C. , Clifton A. , Britton J. 
Published: November 2007

AbstractWe report the case of a giant fusiform aneurysm of the petrous internal carotid artery in a 15-year-old patient who had presented with headache, hearing loss and Horner's syndrome. Definitive radiological diagnosis was made by non-invasive imaging techniques, including magnetic resonance angiography (MRA). The aneurysm was obliterated by endovascular balloon occlusion following successful tolerance of test occlusion of the internal carotid artery.
Adenocarcinoma of the larynx – a distant metastasis from a rectal primary
Authors: Hilger Andreas W. , Prichard Andrew J. , Jones Terry 
Published: November 2007

AbstractLaryngeal metastases from remote primary tumours are uncommon. They derive mostly from melanomas or renal cell carcinomas. The generally rare laryngeal adenocarcinomas can only be classified as metastatic tumours in the presence of a distant primary of the same histology. Only five cases of a laryngeal secondary originating from adenocarcinoma of the large bowel have been reported in the world literature. A further case is presented which to our knowledge is the first to arise from the rectum, a site which suggests haematogenous tumour spread. This paper emphasizes the need for the search of synchronous metastatic disease and discusses the therapeutic options on the grounds of current management of singular colorectal secondaries.
Pleomorphic lipoma of the parotid gland
Authors: Graham C. T. , Roberts A. H. N. , Padel A. F. 
Published: November 2007

AbstractLipomata are rare tumours of the parotid gland. The plemorphic lipoma represents an unusual histological variant of the benign lipoma. We report a case of a pleomorphic lipoma arising in the parotid gland. Only one case of a similar nature has previously been recorded. This tumour is benign, was fully excised and recurrence is not expected.