bluuebunny/crossref_metadata_2025_split huggingface dataset:
Arginine vasopressin, ghrelin, 5-hydroxyindoleacetic acid, and substance P do not appear to be reliable biomarkers of nausea in dogs
Authors: Seger Cameron B. , Muñoz Kirk A. , Adams Laura R. , Kamr Ahmed , Lerche Phillip , Pereira Carolina H. Ricco , Wanstrath Audrey , Toribio Ramiro E. 
Published: February 2025

Abstract

Objective
To determine if ACTH, cortisol, arginine vasopressin (AVP), ghrelin, 5-hydroxyindoleacetic acid (5-HIAA), and substance P (SP) blood biomarkers associated with nausea in humans have similar associations in dogs.

Methods
7 healthy, mixed hound dogs were nausea scored using videotaped observations, and concentrations of ACTH, cortisol, AVP, ghrelin, 5-HIAA, and SP were measured in blood at baseline, after 0.5 mg/kg, IM, morphine administration, and following administration of the treatment drug. Data collection occurred from October 20 through November 24, 2023. Treatments were saline 0.1 mL/kg (S) and propofol 0.5 mg/kg (P1), 1.0 mg/kg (P2), and 1.5 mg/kg (P3) administered IV 20 minutes after morphine administration using a randomized, crossover design with a 7-day washout between treatments.

Results
Nausea scores increased at 5 minutes and over time in all treatments. Adrenocorticotropic hormone concentrations were lower in P2 versus P1, P2 versus S, and P3 versus S at the 50-minute time point. At 50 minutes, cortisol concentrations were lower in P3 versus S, P2 versus S, and P3 versus P1. There were no statistically significant differences in AVP, ghrelin, 5-HIAA, or SP concentrations between treatments or over time.

Conclusions
AVP, ghrelin, 5-HIAA, and SP did not correlate with nausea signs in dogs. Additionally, propofol, at the subhypnotic doses administered, did not significantly decrease signs of nausea.

Clinical Relevance
ACTH and cortisol, but not AVP, ghrelin, 5-HIAA, and SP, concentrations appeared to be associated with signs of nausea in dogs. Propofol was not effective at decreasing signs of nausea at the administered dosages.
Liposomal bupivacaine use is not associated with a higher rate of surgical site infections or multidrug-resistant infections in dogs undergoing anal sacculectomy
Authors: Goldblatt Benjamin H. , Tremolada Giovanni 
Published: February 2025

Abstract

OBJECTIVE
To describe whether infiltration of liposomal bupivacaine (LB) is a risk factor for the development of surgical site infection (SSI) in anal sacculectomy (AS) and compare bacterial isolates from SSIs in animals that received LB and those that did not.

METHODS
A medical record review was performed at Colorado State University for dogs undergoing AS between August 2019 and October 2024. Data retrieved included signalment, reason for AS, anesthesia time, additional procedure performed, perioperative and postoperative antibiotic administration, use of LB, development of SSI, and bacterial isolates.

RESULTS
The study population included 105 dogs that underwent a total of 121 ASs. In 18 of 105 cases (17.1%), SSI was noted. For the cases where LB was infiltrated intraoperatively, the rate of SSI was 17.5% (11 of 63). In cases where LB was not used, the rate of SSI was 16.7% (7 of 42). The most common bacterial isolates were Escherichia coli and Enterococcus spp. Of the 10 cultures, 8 had resistance profiles and 2 of 8 (25%) were found to have multidrug-resistant bacteria present, with no difference between the groups.

CONCLUSIONS
This study did not show that LB was a significant risk factor for the development of SSI or multidrug-resistant infections.

CLINICAL RELEVANCE
Incisional infiltration of LB does not seem to be associated with a higher rate of SSI or higher rates of multidrug-resistant infections in dogs undergoing AS.
Comparison of Language Models for English-Latvian Semantic Search
Authors: Kucheravy Artem , Jēkabsons Gints 
Published: February 2025

Abstract
In this study, ten language models are explored and compared in an English-Latvian semantic information retrieval setting, where the indexed collection of documents is written in English while the query documents are written in Latvian. Currently, no similar research has been done regarding the Latvian language. A dataset of 77736 pairs of articles from Latvian and English Wikipedia was created, transformed into embedding vectors, and used for retrieval experiments with brute force search, Hierarchical Navigable Small World method, and Inverted File Indexing method. The LaBSE language model achieved the best performance for short texts and a version of Sentence-BERT and E5-large for long texts.
L’Appréciation des images en arts plastiques dans les programmes scolaires brésiliens et québécois
Authors: Lemonchois Myriam , Francez Leticia 
Published: February 2025

Au Québec et au Brésil, l’appréciation est désormais reconnue essentielle face aux images qui envahissent les espaces, en particulier les espaces numériques. Au cours des dernières décennies, l’importance accordée à l’appréciation des images a contribué à la reconnaissance des arts plastiques comme une discipline scolaire à part entière. Cependant, depuis peu et dans les deux pays, les programmes éducatifs adoptent une autre position, et celle-ci, à notre avis, met en danger l’enseignement des arts dans les écoles. L’appréciation des images est un ajout récent à ces programmes et son traitement y révèle des changements récents opérés par l’éducation, changements qui vont à l’encontre des recherches dans l’enseignement des arts. Pour appuyer nos propos, nous analysons l’appréciation en arts plastiques dans les écoles au Québec et au Brésil.
Mots-clés : enseignements des arts plastiques, appréciation des images, programmes scolaires, Brésil, Québec, DBAE
Libertad o muerte, un lema para dos naciones: similitudes y diferencias entre las revoluciones griega y uruguaya (1811-1821)
Authors: Silva Katia Marina 
Published: February 2025

Recepción: 17 de febrero de 2024 ISSN (impreso): 1665-8973
Aceptación: 16 de mayo de 2024 ISSN (digital): en trámite
Uruguay y Grecia cumplen doscientos años de su independencia. Este artículo propone analizar tres dimensiones de su proceso emancipatorio: el origen de las revoluciones y el proyecto político, el papel desempeñado por gauchos y kleftes y el rol de Gran Bretaña en la creación de ambos Estados nacionales. El estudio se justifica por la escasez de antecedentes que aborden posibles paralelos. La metodología es de tipo comparativo, basada en una revisión bibliográfica de fuentes primarias y secundarias. Se identifican similitudes, que incidieron en la construcción e identidad nacionales: la ausencia de un proyecto político definido previo a la independencia; el uso de kleftes y gauchos como combatientes, su exclusión política de los Estados independientes y su recuperación ulterior como símbolos de la nación; el rol predominante de Gran Bretaña en el surgimiento de los Estados nación.
Palabras clave: Revolución, independencia, construcción nacional, Grecia, Uruguay.

Freedom or death, one motto for two nations: Similarities and differences between the Greek and Uruguayan Revolutions (1811-1821)
Uruguay and Greece celebrate two hundred years of their independence. This article proposes to analyze three dimensions of its emancipatory process: the origin of revolutions and their political project, the role played by gauchos and kleftes and that of Great Britain in the creation of national States. The study is justified by the scarcity of antecedents that address possible parallels. The methodology is comparative, based on a bibliographic review of primary and secondary sources. Similarities are identified, which influenced national construction and identity: the absence of a defined political project prior to independence; the use of kleftes and gauchos as combatants, their political exclusion from independent States and their subsequent recovery as symbols of the nation; the predominant role of Great Britain in the emergence of nation states.
Key words: Revolution, independence, national construction, Greece, Uruguay.
EXEGESE DE LUCAS 20:27-40 HAVERÁ CASAMENTO NO CÉU?
Authors: Mattos Igor Felipe L. de O. B. , Torres Milton Luiz 
Published: February 2025

O casamento idealizado por Deus é uma bênção na vida do ser humano. Uma vez que era plano dEle que o ser humano pudesse se realizar e aprender através dessa instituição, não há por que crermos que, com Sua volta e a restauração de todas as coisas, deixe de existir o casamento na eternidade. Assim, o objetivo geral deste trabalho foi examinar a resposta de Cristo dada aos saduceus sobre o casamento em Lucas 20:27-40. O objetivo específico foi, por sua vez, definir se há escopo para a instituição do casamento na doutrina escatológica do céu. Para tanto, a metodologia empregada nesta pesquisa foi a exegese do trecho de Lucas sob estudo. Na análise da perícope de Lucas, foi possível notar, na resposta de Jesus ao partido descrente na ressurreição, uma confirmação dessa crença. Essa certeza podia ser fundamentada nas Escrituras, em relatos como o da sarça ardente, apontado por Jesus, e no poder de Deus, outro motivo para não desacreditar em tal promessa. Cristo diz que seremos como os anjos, em outras palavras, seres imortais, filhos de Deus. Não será mais necessário o levirato, pois todos viverão eternamente, numa nova ordem de coisas.
Diagnosis and management of a mild case of cerebral amyloid angiopathy-related inflammation: A case report
Authors: Baskaran Archit Bharathwaj , Kozel Olivia A , Jhaveri Aditya , Vadapally Pranay , Agwu Chibueze , Kothari Sachin A , Bulwa Zachary B 
Published: February 2025

Background:
Cerebral amyloid angiopathy (CAA) is a neurological condition characterized by the deposition of amyloid beta particles within the cerebral vasculature over time. A rare complication of CAA is an autoimmune inflammatory syndrome to cerebrovascular amyloid deposits. In this report, we present a case of CAA-related inflammation (CAA-RI) and discuss the diagnostic and management considerations when encountering this pathology.

Case Description:
A 69-year-old man with a history of hypertension, hyperlipidemia, obstructive sleep apnea, benign prostatic hyperplasia, and major depressive disorder presented to the clinic with rapidly progressive cognitive impairment over the preceding 2 months. Magnetic resonance imaging (MRI) of the brain demonstrated white matter hyperintense lesions associated with innumerable microbleeds asymmetrically concentrated in the right parietal lobe, with subtle hyperattenuation of the sulci. These findings suggested a diagnosis of probable CAA-RI. The patient was started on intravenous methylprednisolone, one gram daily for 5 days, followed by a prolonged prednisone taper over the next 6 weeks.

Conclusion:
Patients with CAA-RI typically present with cognitive decline, followed by focal neurologic deficits, seizures, and headaches. On MRI of the brain, T2/fluid-attenuated inversion recovery asymmetric hyperintense white matter lesions local to cerebral microbleeds are characteristic. Management of CAA-RI involves high-dose corticosteroids with emerging investigation of immunosuppressive therapies.
Rare presentation of acute anterior cord syndrome due to fibrocartilaginous embolism in a pediatric patient following minor trauma
Authors: Alshehri Ali , Alanazi Rahaf , Dokhi Haifa Bin , Alshalaan Hesham , Alqahtani Hanan , Alhamied Nawaf , Aldabas Haya , Althobaiti Khalid , Alali Hamzah , Alharbi Naif , Alshaya Wael 
Published: February 2025

Background:
Anterior spinal cord syndrome (ASCS) is an extremely rare condition defined as an infarction of the anterior two-thirds of the spinal cord. The type and timing of the clinical presentation, combined with the radiological findings, can provide a focused clinical picture of the severity and outcomes and direct the management plan. We present a rare case report of a pediatric patient with ASCS in acute settings due to a fibrocartilaginous embolism (FCE).

Case Description:
We report a 10-year-old girl who was medically and surgically free. She presented with ASCS features 30 min after lifting her younger sister in her back. The clinical presentation consisted of bilateral lower limbs weakness 0/5 according to the medical research council’s scale, weak anal tone, with pain and temperature significantly altered and absent up to T4 level. A diagnosis of anterior spinal infarction due to FCE was made after excluding the possible anterior cord syndrome etiologies. The management consisted of aspirin and extensive physiotherapy, and she significantly recovered over 1 month.

Conclusion:
We report a rare case of acute presentation of a pediatric patient with ASCS due to FCE. The timing of a diagnosis affects clinical results. Correlating the radiological findings to the clinical presentation can narrow the differential diagnosis. The literature on the management of these cases is lacking. Animal studies reported a trial of medical therapy.
Ensemble Machine Learning Applied to Assessment and Mapping of Low and Moderate Slopes Landslide Susceptibility in Hamam Nbail, Algeria
Authors: Harfouche Ameur  , Djerbal Lynda  , Bahar Ramdane 
Published: February 2025

The municipality of Hammam N’bails, located 37 km east of the capital of Guelma province (eastern Algeria), is accessible via RN20 and CW19 roads. It borders the municipalities of Khemissa and El Henancha in Souk-Ahras province. With a population of approximately 16,000 and covering an area of 164 km², this region is characterized by mountainous terrain, with elevations ranging from 112 to 292 meters. The area experiences cold, snowy winters and hot, dry summers, with an average annual rainfall of about 600 mm. Renowned for its natural thermal springs, Hammam N’bails is also a notable tourist destination. The rugged topography of the region leads to frequent landslides, particularly on medium and low slopes. Landslide susceptibility is assessed using raster calculators in ArcGIS and efficient machine learning algorithms, such as Decision Trees, Bagging, Random Forest, SVM, and MLP. Factors considered in the analysis include slope, elevation, geology, aspect, proximity to streams and roads, land cover, and rainfall. The performance of these models is evaluated using ROC-AUC curves, providing a robust method to understand and mitigate geological risks in this area.
Pathogenesis of nervous system lesions and clinical syndromes of the new coronavirus infection COVID-19
Authors: Patsenko M. B. , Glotko V. L. , Shirokov E. A. , Gaivoronskii I. N. 
Published: February 2025

Based on the analysis of literature data, the issues of neurological complications after the new coronavirus infection COVID-19 are highlighted. There is little evidence for a direct mechanism for the neuroinvasiveness and neurotoxicity of the SARS-CoV-2 virus. Various mechanisms of coronavirus penetration into the brain are discussed - anterograde and retrograde, neuronal spread, transcriptional and hematogenous pathways. Retrograde/anterograde transport and transsynaptic transfer of the virus have been confi rmed by in vitro studies. Penetration of the virus into the central nervous system is also possible by spreading through peripheral nerves, for example, along the vagus nerve, which innervates the lungs and intestines. There are several possible mechanisms for the spread of SARS-CoV-2 across the blood-brain barrier: circulation of viral particles in the bloodstream, viral transcytosis through endothelial cells of blood vessels and capillaries, infection of leukocytes by viruses and transfer of viruses through the blood-brain barrier. Hypoxia caused by cytokine storm and respiratory distress lead to disruption of brain metabolism and the development of neurological complications.Aim. Analysis of literature data on the study of early and long-term manifestations of neurological disorders and diseases during a new coronavirus infection, postCovid syndrome (long COVID-19), as well as after vaccination.Results. Among the large number of nervous system disorders, there are five main types with long-term neurological complications associated with COVID-19: 1) encephalopathy with delirium/psychosis; 2) inflammatory syndromes of the central nervous system; 3) ischemic strokes; 4) peripheral neuropathies, in particular Guillain–Barre syndrome and brachial plexopathies; 5) other disorders of the central nervous system.
Nodular goiter and anamnesis of COVID-19: clinical and pathogenetic relationships, sonographic and cytological features
Authors: Nekrasov A. I. , Pochinka I. G. , Strongin L. G. , Orlinskaya N. Yu. , Lugovaya L. A. , Melnichenko O. V. 
Published: February 2025

There is literature data on the development of destructive thyroiditis in patients with COVID-19, which may increase the risk of thyroid pathology in the post-COVID period. Special attention is paid to autoimmune thyroid diseases, while the impact of COVID-19 on nodular goiter (NG) has been studied little.The aim of this study was to investigate the sonographic and cytological features of nodular goiter in patients with a recent history of COVID-19. Materials and Methods: A total of 132 patients who sequentially presented to a healthcare facility between October and May 2021-2022, where they were fi rst diagnosed with nodular goiter, were examined. Of these, 36 denied a history of COVID-19 (control group), while 96 had experienced it 2-9 months prior (main group).Results: According to sonographic data, there were more patients in the main group with microcalcifications (17 (17.8%) vs. 2 (5.6%), p = 0.047), cystic components of nodules (22 (22.9%) vs. 2 (5.6%), p = 0.015), and hypoechoic nodules (23 (23.9%) vs. 4 (11.1%), p = 0.078). In the main group, cytological signs of degenerative changes in thyrocytes combined with macrophage clusters were more frequently observed, which is a nonspecifi c but common manifestation of the consequences of destructive thyroiditis (16 (39.0%) vs. 2 (10.0%), p = 0.017).Conclusion: Nodular goiter identified in the post-COVID period is characterized by an increased prevalence of microcalcifi cations, a tendency towards reduced echogenicity of nodules, as well as cyst formation against a background of degenerative changes in thyroid tissue. The features of nodular goiter identified in the post-COVID period do not exclude a propensity for oncogenic disorders.
Autoimmune gastritis and Helicobacter pylori infection: how do these diseases relate to each other?
Authors: Sheptulin A. A. , Rabotyagova Yu. S. 
Published: February 2025

The article discusses the relationship between autoimmune gastritis and Helicobacter pylori (H. pylori) infection. The prevailing point of view in the literature is that Hpylori infection can act as a trigger factor, contributing to the development and progression of autoimmune gastritis due to the phenomenon of antigen mimicry. At the same time, there are publications on the protective effect of H. pylori infection in relation to the occurrence of autoimmune gastritis and the absence of a link between these diseases. Recent data indicate that the presence of Hpylori infection in patients with autoimmune gastritis contributes to the progression of atrophic changes of the mucous membrane and an increased risk of gastric cancer, which makes it justified to carry out eradication therapy in such cases, which allows to prevent the progression of the disease and the development of complications.
The effect of postoperative anesthesia on cognitive impairment in patients
Authors: Kochubeinik N. V. , Groshilin V. S. , Kubasov R. V. , Zakrevsky Yu. N. , Shatov D. V. , Kubasova E. D. , Linchenko S. N. , Korobitsyn A. P. 
Published: February 2025

The study of the problem of postoperative cognitive impairment arose from the first moment of anesthesia usage. Over the long history of observations, enough clinical information has been accumulated, however, sometimes it is contradictory and difficult to understand. In most cases, the connection between the fact of surgical intervention with the use of anesthesia and a slowdown in neurocognitive recovery in patients has been confi rmed. There is still an ongoing debate about whether the effects on cognitive abilities can be explained either by the anesthetics themselves or by other factors.The aim of the work is to use a narrative review to study modern ideas about the effect of anesthesia on the occurrence of cognitive impairment and the further development of cognitive dysfunctions.Material and methods. To analyze the literature, sources from the international databases Web of Science, Scopus, PubMed, as well as the national library system eLibrary were used.Results and discussion. The review made it possible to collect the results of long-term clinical observations, as well as experimental studies. Several hypotheses have been put forward about the potential mechanisms triggering the occurrence and development of postoperative cognitive disorders, commonly referred to as postoperative cognitive dysfunction. In particular, special attention was paid to changes in the content of Aß- and Tau-protein substances, increased immunological markers of inflammation, impaired regulation of calcium, and mitochondrial dysfunction. All these mechanisms cannot be considered separately. It represents a complex of interrelated, consistent phenomena. Due to the increasing prevalence of various forms of dementia among the population, there is a need to solve the problem of a deeper study of potential factors affecting postoperative cognitive impairment.Conclusions. Contemporary researchers are faced with the task of further studying the risk factors of postoperative cognitive impairment, their systematization, development and implementation in clinical practice. New methods of anesthesia in surgical interventions involve the modernization of techniques that reduce the potential risk of cognitive dysfunction.