bluuebunny/crossref_metadata_2025_split huggingface dataset:
Quantitative Assessment of Water Resources: Empirical Methods and Mapping Recharge Zones: Case Study (Eastern Tunisia)
Authors: BARREK Aziza , Msaddek Mohamed Haythem , May Moufida El , Kouaied Amal , Askri Khaoula , Zouhri Lahcen , CHENINI Ismail 
Published: March 2024

Abstract

Groundwater is considered the primary water resource for drinking, irrigation, and industrial purposes. Excessive groundwater pumping, driven by increasing water demand, particularly in the agricultural sector, leads to groundwater scarcity. Groundwater recharge is the most important process contributing to water sustainability. In this paper, two approaches have been combined to establish a groundwater recharge susceptibility map. The first approach is based on empirical formulas used to estimate quantitative groundwater recharge, namely Chaturvedi, modified Chaturvedi, Sehgal, Krishna Rao, and Bhattacharya, applied to the El Fahs Plain aquifer. The second approach, used to map sustainable groundwater recharge areas, is based on Analytic Hierarchy Process (AHP) multicriteria analysis. To delineate aquifer suitability for groundwater recharge, eight parameters were considered: soil type, land cover, drainage density, lithology, Normalized Difference Vegetation Index, slope, transmissivity, and rainfall. The impact of each factor was weighted, and this method was applied to the El Fahs Plain shallow aquifer. Results indicate that the recharge coefficients obtained from the empirical formulas are 0.143, 0.130, 0.114, 0.010, and 0.089 for Chaturvedi, modified Chaturvedi, Sehgal, Krishna Rao, and Bhattacharya, respectively. The findings suggest that 37% of the aquifer area has very good and good recharge suitability. The results were validated by the Receiver Operating Characteristics curve, with an accuracy of prediction reaching 89.3%. The primary benefit of this research is to enhance the efficiency of mapping groundwater recharge zone suitability.
Prognostic Indicators for Colorectal Cancer Patients Undergoing Curative Resection: Insights from Albumin, Lymphocyte Count, and RAS Mutations
Authors: Miyata Toshiya , Hayama Tamuro , Ozawa Tsuyoshi , Nozawa Keijiro , Misawa Takeyuki , Fukagawa Takeo 
Published: March 2024

Abstract
Colorectal cancer (CRC) poses a significant global health challenge, demanding reliable prognostic tools to guide treatment decisions. This study introduces a novel prognostic scoring system, the Albumin-Total Lymphocyte Count-RAS Index (ALRI), integrating serum albumin, lymphocyte count, and RAS gene mutations. A cohort of 445 stage I–III CRC patients undergoing curative resection was analyzed, revealing ALRI's association with clinicopathological factors, including age, tumor location, and invasion depth. The ALRI demonstrated superior prognostic value, with a cutoff value of 2 distinguishing high and low-risk groups. The high-ALRI group exhibited elevated rates of recurrence. Univariate and multivariate analyses identified ALRI as an independent predictor for both 5-year recurrence-free survival (RFS) and overall survival (OS). Kaplan-Meier curves illustrated significant differences in RFS and OS between high and low-ALRI groups, emphasizing ALRI's potential as a prognostic marker. Importantly, ALRI outperformed existing nutritional indices, such as CONUT and NLR, in predicting overall survival. The study underscores the comprehensive insight provided by ALRI, combining inflammatory, nutritional, and genetic information for robust prognostication in CRC patients. This user-friendly tool demonstrates promise for preoperative prognosis and personalized treatment strategies, emphasizing the crucial role of inflammation and nutrition in CRC outcomes.
Deficit Irrigation practices on Broccoli Growth in a Natural Ventilated Net-cum-Polyhouse
Authors: Sojitra M.A , Satasiya R.M , Vadaria K.N , Rank H.D , Chauhan P.M 
Published: March 2024

Abstract
The aim of this study was to determine the effect of irrigation stress on yield and yield attribute at various growth stages of broccoli under natural ventilated net-cum-polyhouse system. The research experiment was carried out at Junagadh Agricultural University, Junagadh, Gujarat, India, for two years, 2020-21 and 2021-22. The irrigation stress was imposed on 0%, 20%, 40% and 60% of the ETc at the initial, middle and end stages of the crop, respectively. The ETo was calculated by the standard and well-accepted FAO-56 method. The yield attributeparameters, such as stem diameter, plant height, number of leaves per plant and plant canopy were measured at the respective growth stages. However, the days taken to harvest, curd diameter, curd weight and yield were measured at the time of harvesting. The effects of irrigation stress level on crop growth stage were significant for stem diameter, plant height, number of leaves per plant, plant canopy, curd diameter, curd weight and yield. The interaction effect of stress imposed on crop growth stage and irrigation stress level on stem diameter, plant height, plant canopy, curd weight and yield was significant. However, the number of leaves per plant, days taken to harvest and curd diameter were not significantly different. Under irrigation stress, the application of 20% ETC at the initial and end stages promoted a greater yield in broccoli cultivation. Moreover, the yield was on par with that under irrigation stress which reached 60% at the initial stage and 40% at the end stage of the crop. It is advisable to impose irrigation stress at the initial stage and end stage of the broccoli crop when water resources are scarce under natural ventilated net-cum-polyhouse. However, irrigation stress imposed at the middle stage significantly affects broccoli yield.
Why do patients prefer tertiary hospitals?
Authors: Ji Seokmin , Park Sewon , Choi Mankyu , Lee Munjae 
Published: March 2024

Abstract

Background: Tertiary hospital utilization for patients with mild diseases creates inefficiencies in medical utilization for medical consumers and providers, collapses the healthcare delivery system, and has negative consequences for the public health system. This study aims to identify the factors that lead to the selection of tertiary hospitals and the medical needs of patients with mild diseases. We evaluate the value of using medical institutions by comparing and analyzing regional and individual patient characteristics.
Methods: The travel cost method based on the travel cost incurred according to the consumer's temporal choice, was used to evaluate the medical use. We considered data from Ajou University Hospital from 2017 to 2022. The variables used for travel costs are travel costs, time costs, and medical costs. The Quantum Geographic Information System(QGIS) network analysis was used to calculate travel costs and time costs, and independent sample t-tests and analysis of variance (ANOVA) were used to compare the evaluated values between groups.
Results: The analysis revealed that travel costs were the highest for patients with diabetes. Regarding personal characteristics, men exhibited higher rates than women, and individuals under 65 years of age and those receiving type 2 medical benefits demonstrated higher travel costs. Travel costs and outpatient visit rates for mild diseases exhibited a direct proportional relationship. We compared the total economic value assessed for each type of mild disease and found the highest value for diabetes patients with the highest number of outpatient visits.
Conclusion: These findings highlight the importance of incorporating patient segmentation into policy formulation to alleviate the overcrowding of patients with mild illnesses in tertiary care hospitals. Furthermore, they advocate adopting a primary care-centered approach to enhance the healthcare delivery system and address imbalances in community healthcare resources.
Restoring Social Deficits in IRSp53-Deleted Mice: Chemogenetic Inhibition of Ventral Dentate Gyrus Emx1-Expressing Cells
Authors: Kim Yangsik , Kim Su Hyun , Lee Bomee , Lee Seong Mi 
Published: March 2024

Abstract

IRSp53 is a synaptic scaffold protein reported to be involved in schizophrenia, autism spectrum disorders, and social deficits in knockout mice. Identifying critical brain regions and cells related to IRSp53 deletion is expected to be of great help in the treatment of psychiatric problems. In this study, we performed chemogenetic inhibition within the ventral dentate gyrus (vDG) of mice with IRSp53 deletion in Emx1-expressing cells (Emx1-Cre;IRSp53 flox/flox). We observed the recovery of social deficits after chemogenetic inhibition within vDG of Emx1-Cre;IRSp53 flox/flox mice. Additionally, chemogenetic activation induced social deficits in Emx1-Cre mice. CRHR1 expression increased in the hippocampus of Emx1-Cre;IRSp53 flox/flox mice, and CRHR1 was reduced by chemogenetic inhibition. Htd2, Ccn1, and Atp61l were decreased in bulk RNA sequencing, and Eya1 and Ecrg4 were decreased in single-cell RNA sequencing of the hippocampus in Emx1-Cre;IRSp53 flox/flox mice compared to control mice. This study determined that the vDG is a critical brain region for social deficits caused by IRSp53 deletion. Social deficits in Emx1-Cre;IRSp53 flox/flox mice were recovered through chemogenetic inhibition, providing clues for new treatment methods for psychiatric disorders accompanied by social deficits.
Evolution of the Internal Structure and Physical Properties of Tongxin Sandstone Due to High Temperature
Authors: Jiang Guanghui , Wang Jintao , Wen Jinhao , Liu Xingzong 
Published: March 2024

Abstract

The thermal stability of the surrounding rock is pivotal to the efficient and safe production of high-temperature fluidized mining engineering. To investigate the thermal stability of rocks, this paper takes the roof sandstone of Tongxin coal mine as the research subject and tests the changes in various physical properties such as mass, size, wave velocity, porosity, and permeability with temperature. Additionally, thermal analysis testing and microscopic observations were conducted. The analysis yielded the following conclusions: (1) The thermal stability of the surrounding rock is pivotal to the efficient and safe production of high-temperature fluidized mining engineering; (2) The alterations in Tongxin sandstone's physical properties primarily stem from dehydration, thermal stress, quartz phase transitions, and kaolinite dehydroxylation. (3) The analysis of the pyrolysis process can predict the evolution rules and threshold temperature of various physical parameters efficiently; (4) a model that links wave velocity and permeability in sandstone at different temperature has been formulated, predicated on the interrelation of physical properties; (5) Based on the evolution rules of various physical properties and the analysis of the pyrolysis process, along with microscopic observation results, the evolution rules and mechanisms of the internal structure of Tongxin sandstone after heating were obtained.
The Bulk and Solution Properties Investigation of Multiblock Polyether
Authors: Jiang Xiaoxia , Zhang Zhiqing , Jin Xiaoxia , Wang Xiaojie , Bi Yangang , Choi Sukyoung , Dou Fan 
Published: March 2024

Abstract
A series of novel multiblock polyethers, (PEOm-PPOn)k, were synthesized via the anionic polymerization using ethylene glycol as the initiated core. Respectively, they were named as E340, E540 and E740, due to the block number (3, 5, 7) and the content of ethylene oxide (EO, 40 w%), which were confirmed by the Fourier transform infrared (FT-IR), 1H NMR, and GPC. Moreover, their bulk properties were determined as pseudoplastic fluid by the rotational rheometer. It was found that their solubility and surface tension were all gradually weakened with the addition of block numbers. Nevertheless, the dynamic modulus tended contrary trends. As confirmed to thier microemulsion performance, it was more easier to be destroyed the hydrophilic-lipophilic balance for the E740. Herein, the E740 could be potentially used as micro-emulsion demulsification and wastewater treatment.
High-capacity uranium extraction from seawater through constructing synergistic multiple dynamic bonds in confined spaces
Authors: Zhu Guangshan , Yuan Ye , Cao Doudou , Fengchao Cui , Zhang Cheng , Yang Yajie , Song Yingbo , Cao Jiarui , Zheng Yue , Chen Shusen , Song Yan , Wang Fengju 
Published: March 2024

Abstract

Seawater is the largest uranium reserve in the world, and the efficient extraction of uranium from seawater facilitates the sustainable development of the nuclear industry for thousands of years. However, conventional extraction processes must suffer the dissociation of CO32− ions from [UO2(CO3)3]4− anions to bind the uranyl core, which has a high energy barrier, resulting in the poor selectivity and long working times. Here, we combine a molecular templating strategy to synthesize five hydroxy-rich covalent organic frameworks (COFs) with tunable nanopore sizes (from 0.6 to 2.5 nm). In the 1.1-nm-sized COF cavity, hydroxyl groups coupled with the hydrogen-bonded NH4+ cations selectively bind uranyl tricarbonate ions via synergistic electrostatic and hydrogen-bonding interactions. This framework exhibits high uranium-extraction capability with a removal ratio of >99.99 % in 400 min. Notably, a record uranium-adsorption uptake is achieved with a capacity of 23.68 mg g−1 in 7 days from natural seawater, surpassing that of classical amidoxime-based adsorbents by a factor of 350%.
Enhancing Cellulose Hydrolysis via Cellulase Immobilization on Zeolitic Imidazolate Frameworks Using Physical Adsorption
Authors: Sun Liqun , Xu Chaozhong , Tong Shanshan , Gu Xiaoli 
Published: March 2024

Abstract

This study investigates the immobilization of cellulase on zeolitic imidazolate frameworks (ZIFs) by physical adsoption, specifically ZIF-8-NH2 and Fe3O4@ZIF-8-NH2, to enhance enzymatic hydrolysis efficiency. The immobilization process was thoroughly analyzed, including optimization of conditions and characterization of ZIF carriers and immobilized enzymes. The impacts on the catalytic activity of cellulase under various temperatures, pH levels, and storage conditions were examined. Additionally, the reusability of the immobilized enzyme was assessed. Results showed the cellulase immobilized on Fe3O4@ZIF-8-NH2 exhibited a high loading capacity of 339.64 mg/g, surpassing previous studies. Its relative enzymatic activity was found to be 71.39 %. Additionally, this immobilized enzyme system demonstrates robust reusability, retaining 68.42 % of its initial activity even after 10 cycles. These findings underscore the potential of Fe3O4@ZIF-8-NH2 as a highly efficient platform for cellulase immobilization, with promising implications for lignocellulosic biorefinery.
Anticipating Solar Flares
Authors: Hudson Hugh 
Published: March 2024

Abstract

Solar flares commonly have a "hot onset precursor event" (HOPE), detectable from soft X-ray observations. This requires subtraction of pre-flare fluxes from the non-flaring Sun prior to the event, fitting an isothermal emission model to the flare excess fluxes by comparing the GOES passbands at 1-8 Å and 0.5-4 Å, and plotting the timewise evolution of the flare emission in a diagram of temperature vs emission measure. The HOPE then appears as an initial "horizontal branch" in this diagram. It precedes the non-thermal impulsive phase of the flare and thus the flare peak in soft X-rays as well. We use this property to define a "flare anticipation index" (FAI), which can serve as an alert for observational programs aimed at solar flares based on near-real-time soft X-ray observations. This FAI gives lead times of a few minutes and produces very few false positive alerts even for flare brightenings too weak to merit NOAA classification.
Synthesis, Spectroscopic, SQUEEZE method/XRD interactions, linear and Nonlinear Optical properties, and antibacterial effect of the ligand/copper(II) complex tetradentate Schiff base: Experimental and Theoretical Studies
Authors: Boudraa Naouel , Assabaa Rachida , Ghichi Nadir , Zaidi Meriem , Hannachi Douniazed , Djedouani Amel , Yahiaoui Ahmed Abderrahim , stoeckli-evans Helen 
Published: March 2024

Abstract

This study focuses on the synthesis, characterization, and biological evaluation of a novel N2O2 donor Schiff base ligand: N,N'-bis(2-hydroxypropiophenone)-1,2-ethanediamine L and its’ copper(II) complex CuL Extensive spectroscopic methods including 1H and 13C NMR, FT-IR, Raman and UV-Vis spectroscopy were employed for the detailed characterization of these compounds. The structure of the CuL complex was elucidated using single-crystal X-ray crystallography, employing the SQUEEZE procedure in PLATON to resolve refinement issues. The antibacterial efficacy of the synthesized compounds was assessed using the disc-diffusion method against a range of bacteria: Staphylococcus aureus, Bacillus cereus (Gram-positive), and Escherichia coli, Pseudomonas aeruginosa, Klebsiella pneumoniae (Gram-negative). Additionally, the study extends to the computational realm, where Density Functional Theory (DFT) and Time-Dependent-DFT (TD-DFT) methods were utilized to analyze the structural optimization, optical properties, and both static and dynamic hyperpolarizabilities of CuL and its analogues with nickel (NiL) and zinc (ZnL). The findings contribute valuable insights into the spectral properties, crystal structure, and biological activities of these Schiff base complexes.
Coupling between maximum temperature and ozone levels in the lower stratosphere and extreme cooling events in Northeast China
Authors: Shi Yu , Evtushevsky Oleksandr , Milinevsky Gennadi , Yu Ruixian , Grytsai Asen , Sun Xiaopeng , Wang Xiaolong 
Published: March 2024

Abstract
The little studied vertical temperature structure between the lower stratosphere and the surface during extreme cooling events in Northeast China is analyzed. Minimum diurnal temperatures in Changchun (44°N, 125°E) in January 2011, 2016, 2018 and 2023 were taken from Meteostat data. NCEP–NCAR reanalysis temperatures in the meridional cross-section between the pressure levels of 1000 hPa and 10 hPa, averaged over 120–130°E, and horizontally at 30–90°N are considered. Meridional profiles of ozone concentration are based on MLS observations and ERA5 reanalysis. In January of the four winters, the temperature in Changchun dropped by 15–24°C, and the coldest days were compared to the warmest days. It has been shown that there were (i) a concerted downward movement of vertical temperature and ozone maxima to the lower stratosphere, (ii) the tropopause descent by about 2–3 km below the warmest lower stratosphere and (iii) pushing down of the cold midtropospheric layer from about 4 km to the surface with the occurrence of extremely cold weather (–28°C to –34°C). Due to the action of stationary planetary waves, the large wave ridge provides a deep southward penetration of cold polar air into Northeast China, bringing the lowest January temperature among the midlatitude regions. Our results highlight the persistent vertical structure of the thermal coupling between the lower midlatitude stratosphere and the surface over four coolings and the role of peak stratospheric temperature and ozone levels in the occurrence of extremely cold weather.
Role of robot-assisted laparoscopy in deep-infiltrating endometriosis with bowel involvement: a systematic review and application of the IDEAL framework
Authors: Ong Hwa Ian , Shulman Nastassia , Nugraha Patrick , Wrenn Stephen , Nally Deirdre , Peirce Colin , Mahmood Uzma , McCormick Jacob , Proud David , Warrier Satish , Fleming Christina , Mohan Helen 
Published: March 2024

Abstract
Aims
This review aims to evaluate the feasibility of robot-assisted laparoscopic surgery (RALS) as an alternative to standard laparoscopic surgery (SLS) for the treatment of bowel deep-infiltrative endometriosis (1). Additionally, it aims to provide guidance for future study design, by gaining insight into the current state of research, in accordance with the IDEAL framework.
Method
A systematic review was conducted to identify relevant studies on RALS for bowel deep infiltrating endometriosis (BDIE) in Medline, Embase, Cochrane Library, and PubMed databases up to August 2023 and reported in keeping with PRISMA guidelines, The study was registered with PROSPERO Registration: CRD42022308611
Results
11 primary studies were identified, encompassing 364 RALS patients and 83 SLS patients, from which surgical details, operative and postoperative outcomes were extracted. In the RALS group, mean operating time was longer (235 ± 112 min) than in the standard laparoscopy group (171 ± 76 min) (p < 0.01). However, RALS resulted in fewer postoperative complications (15.3%) compared to standard laparoscopy (26.5%). Patients in the RALS group experienced a shorter hospital stay (5.3 ± 3.5 days vs. 7.3 ± 4.1 days) (p < 0.01). Research evidence for RALS in BDIE is at an IDEAL Stage 2B of development.
Conclusion
RALS is a safe and feasible alternative to standard laparoscopy for bowel endometriosis treatment, potentially improving rates of intraoperative and overall postoperative complications despite longer operating times.
Hamiltonian Boundary Value Methods (HBVMs) for functional differential equations with piecewise continuous arguments
Authors: Gurioli Gianmarco , Wang Weijie , Yan Xiaoqiang 
Published: March 2024

Abstract

In this paper, a class of high-order methods to numerically solve Functional Differential Equations with Piecewise Continuous Arguments (FDEPCAs) is discussed. The framework stems from the expansion of the vector field associated with the reference differential equation along the shifted and scaled Legendre polynomial orthonormal basis, working on a suitable extension of Hamiltonian Boundary Value Methods. Within the design of the methods, a proper generalization of the perturbation results coming from the field of ordinary differential equations is considered, with the aim of handling the case of FDEPCAs. The error analysis of the devised family of methods is performed, while a few numerical tests on Hamiltonian FDEPCAs are provided, to give evidence to the theoretical findings and show the effectiveness of the obtained resolution strategy.
FLTGAN: A Novel Framework for Enhanced Diabetes Classification in Imbalanced Datasets
Authors: Yang Shuaibin , Liu Wenjun , Wang Sensen , Huang Hui 
Published: March 2024

Abstract

Class imbalances in diabetes datasets are common in datasets in the medical research field, and class imbalances may cause the training effects of machine learning models to be biased toward a larger number of classes, thus affecting the model's ability to predict a small number of classes. In order to solve this problem, this study designed and implemented a diabetes classification model based on Focal Loss Tabular Generative Adversarial Network (FLTGAN) to effectively solve the problem of sample imbalance in uneven datasets. The model, integrating advanced machine learning algorithms, has been validated using two real-world datasets. Comparative results demonstrated that our model significantly outperformed traditional TGAN and SMOTE methods across multiple evaluation metrics, it achieved an F1 score of 0.78, an AUC of 0.84, an accuracy of 0.80, a precision of 0.83, and a recall of 0.75, indicating its superior classification performance. This study confirmed the robust capability of the proposed intelligent diabetes classification method in accurately diagnosing diabetes and addressing class imbalance, offering a new effective tool for the intelligent diagnosis of diabetes.