bluuebunny/crossref_metadata_2025_split huggingface dataset:
ChemInform Abstract: Synthesis of Fluorinated Indoles as RNA Analogues
Authors: Bozilovic Jelena , Engels Joachim W. 
Published: February 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Asymmetric Synthesis of Novel Pseudo‐D‐vinylcyclopropyl Nucleosides Bearing Quaternary Carbon as Potential anti‐Herpesvirus Agent
Authors: Park Ah‐Young , Moon Hyung Ryong , Kim Kyung Ran , Chun Moon Woo , Jeong Lak Shin 
Published: February 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Superconductivity Without Phonons
Authors: Monthoux P. , Pines D. , Lonzarich G. G. 
Published: February 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Single‐Cell Microelectrochemistry
Authors: Schulte Albert , Schuhmann Wolfgang 
Published: February 2008

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Investigating by CD the molecular mechanism of elasticity of elastomeric proteins
Authors: Bochicchio Brigida , Pepe Antonietta , Tamburro Antonio M. 
Published: February 2008

AbstractElastomeric proteins are widespread in the animal kingdom, and their main function is to confer elasticity and resilience to organs and tissues. Besides common functional properties, elastomeric proteins share a common sequence design. They are usually constituted by repetitive sequences with a high content of glycine residues. From a conformational point of view, all the elastomeric proteins since now analyzed show a dynamic equilibria between folded (mainly β‐turns) and extended (polyproline II and β‐strands) conformations that could be at the origin of the high entropy of the relaxed state. As a matter of fact, elastin, lamprin, abductin, as well as the PEVK domain of titin share the same conformational ensemble, thus pointing to a common molecular mechanism as the origin of elasticity. CD spectroscopy represents the proper spectroscopic technique to be used overall because of its particular sensitivity to the presence of PPII structure. Its use in the molecular studies of elastin, abductin, and lamprin as well as the recently analyzed protein resilin will be presented. Chirality, 2008. © 2008 Wiley‐Liss, Inc.
Biomonitoring of Heavy Metals Using the Bivalve Molluscs in Sunderban Mangrove Wetland, Northeast Coast of Bay of Bengal (India): Possible Risks to Human Health
Authors: Sarkar Santosh Kumar , Cabral Henrique , Chatterjee Mousumi , Cardoso Ines , Bhattacharya Asok Kumar , Satpathy Kamala Kanta , Alam Mohammad Aftab 
Published: February 2008

AbstractThe suitability of using four bivalve molluscs (Sanguinolaria acuminata, Anadara granosa, Meretrix meretrix, and Pelecyora trigona) in biomonitoring of heavy metals (Cu, Pb, Cd, Zn, and Hg) collected from intertidal regions of the Sunderban mangrove wetland, northeastern part of the Bay of Bengal, were evaluated. Both speciesdependent variability and temporal variations were pronounced. A high degree of organ specificity was evident in the bivalves where gill and mantle exhibited higher metal accumulation due to ion exchange property of the mucous layer covering these organs while shells represent very poor accumulation. Elevated values of Zn and Cu reflect high potential for biomagnification through marine food chain. Metal concentrations in different body size groups of the bivalves do not follow uniform trend. Correlation coefficient between different metal couplings as tested statistically revealed significant coupling for Pb–Zn, Pb–Cu, Zn–Cu, and Hg–Cu. Concentrations of all the metals in specific organs (visceral mass, mantle and gill) of the bivalves exceeded the safe levels according to the international standards for metals compiled by Food and Agricultural Organization of the United Nations and would be of great risk for human consumption. It is concluded that the mussel and clam are suitable biomonitors to employ in programs designed to assess changes in metal pollution in the Sunderban mangrove wetland.
Structural Diversity in Zinc Phosphates and Phosphinates: Observation of a Lattice Water Dimer Sandwiched Between Phosphoryl Oxygen Atoms
Authors: Pothiraja Ramasamy , Shanmugan Swaminathan , Walawalkar Mrinalini G. , Nethaji Munirathinam , Butcher Ray J. , Murugavel Ramaswamy 
Published: February 2008

AbstractReactions of zinc acetate dihydrate with organic phosphates [(RO)2P(O)(OH)] (R = tBu, Ph) and phosphinic acids [PhR′P(O)(OH)] (R′ = Ph, H) have been investigated in the presence of 1,10‐phenanthroline (phen). While the use of di‐tert‐butyl phosphate (dtbp‐H) results in the formation of [Zn(phen)2(dtbp)(OH2)][dtbp](MeOH)(MeCOOH)(H2O)3 (1), the change of phosphorus source to diphenylphosphate (dpp‐H) yields an interesting phosphate‐bridged dinuclear complex [{Zn(phen)(dpp)}2{μ2‐dpp}2] (2). Mononuclear complexes [Zn(phen)2(dppi)2](H2O)2 (3) and [Zn(phen)2(ppi)2](H2O) (4) have been obtained from similar reactions by the use of diphenylphosphinic acid (dppi‐H) and phenylphosphinic acid (ppi‐H), respectively. The high steric bulk of the dtbp ligand results in the formation of the cationic complex 1, where only one of the dtbp ligands is directly coordinated to the metal atom, leaving the second dtbp molecule as the counter anion. The inorganic core of dinuclear zinc phosphate 2 resembles the single four‐ring (S4R) secondary building unit of framework zinc phosphates. Compounds 3 and 4 are neutral monomeric hexacoordinate complexes with two chelating 1,10‐phen ligands and two monodentate phosphinate ligands. The two lattice water molecules in 3 form an interesting water dimer (H2O)2. These water dimers link the mononuclear zinc complexes in the lattice to form an H‐bonded one‐dimensional polymer. Similarly, the lattice water present in 4 serves to link the zinc phenylphosphinate molecules through hydrogen bonding in the form of a 1‐D polymer. The reaction of the precursor complex [Zn(bpy)2(OAc)](ClO4)·H2O with dpp‐H, dppi‐H, and ppi‐H in methanol leads to the formation of zinc phosphate [Zn(bpy)2(dpp)]2(ClO4)2·H2O (5) and phosphinates [Zn(bpy)2(dppi)]2(ClO4)2 (6) and [Zn(bpy)2(ppi)]2(ClO4)2 (7), respectively. The molecular structures of 1–5 and 7 have been determined by single‐crystal X‐ray diffraction studies. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2008)
Heterometallic M2Cr4 (MII = Sr, Pb) Clusters Assembled by Tris(μ‐aqua) Bridges
Authors: Novitchi Ghenadie , Ciornea Victor , Shova Sergiu , Gulea Aurelian , Costes Jean‐Pierre , Powell Annie K. 
Published: February 2008

AbstractThree heterometallic compounds formulated as [CaCr2(μ‐OH)(μ‐OAc)(nta)2·6H2O]2H2O (I) [M2Cr4(μ‐OH)2(μ‐OAc)2(nta)47H2O]14H2O, [M = Sr2+ (II) Pb2+ (III), H3nta = nitrilotriacetic acid] were prepared and structurally characterised. In all three compounds a common core [Cr(μ‐OH)(μ‐OAc)Cr] containing two different bridging ligands, hydroxido and acetato groups, is present. In I, Ca2+ counterions link the dinuclear chromium units together through outer carboxylate oxygen atoms and a hydrogen‐bonded network, whereas in II and III the nuclearity is extended by the presence of three bridging water molecules linking together two Sr2+ or Pb2+ counterions, which results in hexanuclear M2Cr4 clusters. The temperature dependence of the magnetic susceptibilities of I–III, which were fitted with an isotropic Hamiltonian, yielded antiferromagnetic interaction parameters (J) for I–III close to –14 cm–1. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2008)
Synthesis, Characterization and Reactivity of a η1‐Methylphosphaalkyne Complex, [RuH(dppe)2(η1‐P≡CMe)][CF3SO3]
Authors: Jones Cameron , Schulten Christian , Stasch Andreas 
Published: February 2008

AbstractThe synthesis of the first example of a complex in which methylphosphaalkyne solely η1‐coordinates a metal center, [RuH(dppe)2(η1‐P≡CMe)][CF3SO3] [dppe = 1,2‐bis(diphenylphosphanyl)ethane], is reported. Treatment of this compound with HBF4 (acting as a source of HF) has led to the reduction of the phosphaalkyne and the formation of a rare PF2Et complex, [RuH(dppe)2(η1‐PF2Et)][BF4]. Both complexes have been crystallographically characterized. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2008)
Effects of probiotic bacteria and oils on fatty acid profiles of cultured cream
Authors: Ekinci F. Yesim , Okur Ozge D. , Ertekin Bilge , Guzel‐Seydim Zeynep 
Published: February 2008

AbstractThe aim of this study was to determine the effects of using various probiotic bacteria and plant oils in cultured cream on the fatty acid profiles including conjugated linoleic acids (CLA). L. acidophilus, B. bifidum, S. thermophilus and L. bulgaricus, P. thoenii (jensenii) P126, and P. jensenii B1264 and a mixed culture (blend of L. acidophilus, B. bifidum, S. thermophilus and L. bulgaricus) were used in the fermentation of cream samples at a level of 2%. Cream samples were fortified with sunflower oil, soybean oil and hazelnut oil at a level of 2%. Microbial counts and fatty acid profile analysis were performed. The microbial results demonstrated that fermented cream could be a superior product for the presence of probiotics. Even though the cream samples contained 52% milk fat, in the majority of the samples growth of probiotic bacteria was higher than 106 cfu/g. Concentrations of short‐chain fatty acids such as butyric, caproic and capric acids in cultured cream samples differed depending on the cultures used, while long‐chain unsaturated fatty acids were significantly affected by the plant oil fortification. The highest CLA content was obtained in the sample produced with B. bifidum, containing 0.73 mg of CLA/g fat. The effect of different plant oils on CLA concentration was significant (p >0.05) for HO + YC, SFO + LBYC and SO + LBYC. Results of the study are important for the dairy industry since it is the first publication on fermented cream with improved functional properties. The development of functional cultured cream with plant oils and probiotic bacteria would provide an important alternative dairy product.
Effects of hydrogenation parameters on trans isomer formation, selectivity and melting properties of fat
Authors: Musavi Anar , Cizmeci Melih , Tekin Aziz , Kayahan Muammer 
Published: February 2008

AbstractEffects of hydrogenation conditions (temperature, hydrogen pressure, stirring rate) on trans fatty acid formation, selectivity and melting behavior of fat were investigated. To this aim, soybean oil was hydrogenated under various conditions and fatty acid composition, trans isomer formation, slip melting point (SMP), solid fat content (SFC) and iodine number (IV) of the samples withdrawn at certain intervals of the reactions were monitored. A constant ratio (0.03%) of Nysosel 222 was used in the various combinations of temperature (150, 165 and 180 °C), stirring speed (500, 750 and 1000 rpm) and hydrogen pressure (1, 2 and 3 bar). Raising the temperature increased the formation of fatty acid isomers, whereas higher stirring rates decreased this formation, while changes in hydrogen pressure had no effect or slightly reduced it, depending on other parameters. Results also indicated that the trans fatty acid ratio increased with IV reduction, reached the highest value when the IV was about 70 and decreased at IV < 70 due to saturation. Selectivity values (S21) at that point ranged between 5.78 and 11.59. Lower temperatures and higher stirring rates decreased not only the trans isomer content but also the S21 values at significant levels. However, same effects were not observed with the changes in hydrogen pressure. It was determined that a high SMP does not necessarily mean a high SFC. Selective conditions produced samples with higher SFC but lower SMP, which is possibly because of higher trans isomer formation as well as lower saturation.
Macrocyclic 14‐Membered Ring Diketal Diamines: Synthesis, Conformational Analysis and 99mTc Radiolabeling Evaluation
Authors: Affani Radouane , Auzeloux Philippe , Madelmont Jean‐Claude , Dugat Denise 
Published: February 2008

AbstractChiral and achiral macrocyclic diketal diamines, analogs of cyclams, were synthesized from the previously obtained corresponding diketal dilactams by reduction with lithium aluminum hydride in the presence of a trace amount of triethylamine. In the (15–30) × 10–3 M concentration range, the reaction led mainly to the expected doubly reduced compounds except in the trans‐OMe substituted series (R = Ph, Me), in which it partially stopped at the single reduction stage. A conformational study conducted by liquid NMR spectroscopy and molecular mechanics calculations showed that the most stable conformations were either set in a rectangular [3434]‐type structure for trans‐OMe compounds 7b (R = Me) and 10b (R = H) or stabilized by two intramolecular NH···O hydrogen bonds for all the other macrocyclic diamines. Tc‐99m radiolabeling with the nitrido–technetium core [TcN]2+ gave ≈10–20 % exchange yields. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2008)
Electrochemical Sensor for the Determination of Dopamine in Presence of High Concentration of Ascorbic Acid Using a Fullerene‐C60 Coated Gold Electrode
Authors: Goyal Rajendra Nath , Gupta Vinod Kumar , Bachheti Neeta , Sharma Ram Avatar 
Published: February 2008

AbstractA fullerene‐C60‐modified gold electrode is employed for the determination of dopamine in the excess of ascorbic acid using square‐wave voltammetry. Based on its strong catalytic function towards the oxidation of dopamine and ascorbic acid, the overlapping voltammetric response of both the biomolecules at the bare electrode is resolved into two well‐defined voltammetric peaks with lowered oxidation potential and enhanced oxidation currents. Linear calibration curves for dopamine are obtained using square‐wave voltammetry over the concentration range 1 nM–5.0 μM in 0.1 M phosphate buffer solution at pH 7.2 with a correlation coefficient of 0.9931 and the detection limit (3σ) is estimated to be 0.26×10−9 M. The interference studies showed that the presence of physiologically common interferents (i.e. uric acid, citric acid, tartaric acid, glucose and sodium chloride) negligibly affects the response of dopamine. The practical analytical utility of the method is illustrated by quantitative determination of dopamine in commercially available pharmaceutical formulation and human body fluids, viz. urine and blood plasma, without any preliminary treatment.
Quantitative predictions for DNA two‐dimensional display according to size and nucleotide sequence composition
Authors: Mercier Jean‐François , Kingsburry Christine , Slater Gary W. , Lafay Bénédicte 
Published: February 2008

Abstract2‐D DNA display is a simple separation method that provides a fast and economical way of visualizing polymorphism and comparing genomes. The DNA fragments are separated first according to their size by standard gel electrophoresis and then according to their sequence composition using denaturing gradient gel electrophoresis. First developed by Fischer and Lerman (Cell 1979, 16, 191–200), this method has recently been used to distinguish strains within a bacterial species. The genomic restriction fragments are displayed as spots on a 2‐D surface. Although most of the relevant physical mechanisms are understood, this technique is mostly empirical and remains essentially qualitative. In view of optimizing this procedure, we combine our understanding of the different physical mechanisms at play to develop a complete numerical model to predict the relative coordinates of the spots as a function of the corresponding DNA sequence and of the experimental conditions. We experimentally validate our model by predicting the outcome of a 2‐D display of the λ phage genome. It thus becomes possible to optimize in silico the experimental parameters, to predict whether specific mutations as well as yet undescribed genetic polymorphisms can be resolved, and to assist in interpreting the experimental data.
Improved DNA fragment length estimation in capillary electrophoresis
Authors: Akbari Akbar , Marthinsen Gunnhild , Lifjeld Jan T. , Albregtsen Fritz , Wennerberg Liv , Stenseth Nils C. , Jakobsen Kjetill S. 
Published: February 2008

AbstractIn CE the charged DNA strands are fractionated according to fragment lengths as they migrate through the capillary, since shorter DNA fragments pass through the sieving matrix faster. Multiplexed internal size standards are used to estimate the size of unknown DNA fragments. In the literature there are statements about migration abnormalities for the 250 and 340 bp fragments in the GeneScan‐500 (GS500) internal size standards. Such anomalous migration of size standards could obviously introduce errors in the estimation of unknown fragments. Therefore, a number of analysis programs simply exclude some of these fragments. In the present work we first evaluate the effect of excluding each of the fragments in the internal size standards used in CE. Next, a method which is based on estimating the true values of the anomalous fragments is presented. The results obtained by the new method indicate a significant improvement compared to results obtained when one (or both) of the anomalous fragments in GS500 is (are) excluded or included when estimating the size of unknown DNA fragments. In the higher‐molecular‐weight region, the average error is reduced from 1.91 bp in ABI GeneMapper (excluding 250 bp) to 0.15 bp in the new method (using the estimated values for 250 and 340 bp). In the lower‐molecular‐weight region, excluding both fragments will improve the results by an average of 0.74 bp compared to ABI GeneMapper.
Visualization of interactions between siderophore transporters and the energizing protein TonB by native PAGE
Authors: Choul‐Li Souhaila , Adams Hendrik , Pattus Franc , Celia Hervé 
Published: February 2008

AbstractHorizontal nondenaturing electrophoresis of proteins in polyacrylamide gels was used to observe specific interactions between membrane proteins. The method was particularly well suited for solubilized transporters of the outer membrane of Gram‐negative bacteria, and allowed specific complexes of transporter and the inner‐membrane protein TonB to be isolated. We have used this method to investigate the interactions between four different outer‐membrane transporters, and the TonB proteins from two different organisms. The results show that a stable complex can be isolated on gels for all the proteins studied, but can depend in some cases of the detergent used for solubilization. Furthermore, we observe cross‐species interaction as TonB from a given organism can interact with transporters from another organism.
Complex rectification of Müller cell Kir currents
Authors: Kucheryavykh Yuriy V. , Shuba Yaroslav M. , Antonov Sergei M. , Inyushin Mikhail Y. , Cubano Luis , Pearson Wade L. , Kurata Harley , Reichenbach Andreas , Veh Rüdiger W. , Nichols Colin G. , Eaton Misty J. , Skatchkov Serguei N. 
Published: February 2008

AbstractAlthough Kir4.1 channels are the major inwardly rectifying channels in glial cells and are widely accepted to support K+‐ and glutamate‐uptake in the nervous system, the properties of Kir4.1 channels during vital changes of K+ and polyamines remain poorly understood. Therefore, the present study examined the voltage‐dependence of K+ conductance with varying physiological and pathophysiological external [K+] and intrapipette spermine ([SP]) concentrations in Müller glial cells and in tsA201 cells expressing recombinant Kir4.1 channels. Two different types of [SP] block were characterized: “fast” and “slow.” Fast block was steeply voltage‐dependent, with only a low sensitivity to spermine and strong dependence on extracellular potassium concentration, [K+]o. Slow block had a strong voltage sensitivity that begins closer to resting membrane potential and was essentially [K+]o‐independent, but with a higher spermine‐ and [K+]i‐sensitivity. Using a modified Woodhull model and fitting i/V curves from whole cell recordings, we have calculated free [SP]in in Müller glial cells as 0.81 ± 0.24 mM. This is much higher than has been estimated previously in neurons. Biphasic block properties underlie a significantly varying extent of rectification with [K+] and [SP]. While confirming similar properties of glial Kir and recombinant Kir4.1, the results also suggest mechanisms underlying K+ buffering in glial cells: When [K+]o is rapidly increased, as would occur during neuronal excitation, “fast block” would be relieved, promoting potassium influx to glial cells. Increase in [K+]in would then lead to relief of “slow block,” further promoting K+‐influx. © 2008 Wiley‐Liss, Inc.
Multivariate partial adjustment of financial ratios: a Bayesian hierarchical approach
Authors: Gallizo Jose Luis , Gargallo Pilar , Salvador Manuel 
Published: February 2008

AbstractIn this paper we propose a multivariate extension of the partial adjustment model of financial ratios. To that end, we use a dynamic factor model which assumes that financial ratios measuring, essentially, the same economic–financial dimension of the firm evolve in a similar way, reflecting the evolution of the common factor. The proposed model is hierarchical with three levels. The first describes the relationship between each ratio and its common factor; the second describes the evolution of the common factors over time by means of Lev's (1969) partial adjustment model; and the third analyzes the similarity of firms' adjustment coefficients, taking into account their characteristics. The methodology is applied to the analysis of a set of financial ratios related to the business and financial structure of the firm. Copyright © 2008 John Wiley & Sons, Ltd.