bluuebunny/crossref_metadata_2025_split huggingface dataset:
Synthesis and Antitumor Activity of [3-Acetyl-2,4(3H,5H)-furandionato-O3,O4] [(1R,2R)-cyclohexanediamine]platinum(1+) Ion Complex and Its Derivatives
Authors: Hata Go , Kawai Hideki , Kaneko Tatsuya , Imaoka Takayuki , Kitano Yukishige , Mutoh Masato , Imanishi Hideyo 
Published: April 2006

Abstract
The reaction of dihydroxo[(1R,2R)-cyclohexanediamine]platinum(II) with 3-acetyl-2,4-(3H,5H)-furandiones gave salts consisting of [3-acetyl-2,4(3H,5H)-furandionato-O3,O4] [(1R,2R)-cyclohexanediamine]platinum(1+) ions and enolates of 3-acetyl-2,4-(3H,5H)-furandiones. The complexes show high solubility, and antitumor activity at low doses against murine leukemia L1210 sensitive and resistant to cis-dichlorodiammineplatinum(II).
Intermolecular Ferromagnetic Interaction of 4-(2-Naphthylmethyleneamino)-2,2,6,6-tetramethylpiperidin-1-oxyl
Authors: Tomioka Katsuyuki , Ishida Takayuki , Nogami Takashi , Iwamura Hiizu 
Published: April 2006

Abstract
The magnetic susceptibility and magnetization of a polycrystalline sample of the title compound were measured on a Faraday balance and a SQUID susceptometer. The intermolecular ferromagnetic interaction was indicated by the facts that the χmolT value increased with decreasing temperature and that the magnetization measured at 1.7 and 4.2 K saturated more rapidly than that of a Brillouin function with S = 1/2.
A Convenient Method for Synthesis of 1-Amino-2-tetralones by Photoamination of 2-Alkoxynaphthalenes with Alkylamines
Authors: Yamashita Toshiaki , Yamano Katsuhiko , Yasuda Masahide , Shima Kensuke 
Published: April 2006

Abstract
Irradiation of an acetonitrile-water solution containing 2-alkoxynaphthalene, an amine, and m-dicyanobenzene gave selectively 2-alkoxy-1-alkylamino-1,4-dihydronaphthalenes in relatively good yields. The aminodihydronaphthalenes were acetylated with Ac2O and then treated with BF3·OEt2 to give N-acetyl-1-alkylamino-2-tetralones in good yields.
A New Synthetic Route to β-Hydroxythioethers from Carbonyl Compounds Using Samarium(II) Diiodide (SmI2)
Authors: Yamashita Masayuki , Kitagawa Kazuhiro , Ohhara Takashi , Iida Yoshiko , Masumi Akiko , Kawasaki Ikuo , Ohta Shunsaku 
Published: April 2006

Abstract
In the presence of samarium diiodide (SmI2) in THF, chloromethyl sulfides reacted with carbonyl compounds to give β-hydroxythioethers under mild and neutral conditions in moderate to good yields.
Novel Photo-Memory Effect in Photoconductivity of Conducting Polymer Containing Photochromic Dye
Authors: Kawai Tsuyoshi , Koshido Takashi , Nakazono Masahiro , Yoshino Katsumi 
Published: April 2006

Abstract
Photoconduction of a conducting polymer, poly(9,9-dihexadecylfluorene) containing a photochromic dye, cis-1,2-dicyano-1,2-bis(2,4,5-trimethyl-3-thienyl)ethene, is suppressed upon photoisomerization of the dye from ring-open form to ring-closed form but recovered by the reverse photoisomerization. The reversible memory effect in the photoconduction has been discussed on the basis of the energy states of the dye and those trapping effects on the photo-carriers in the conducting polymer.
Trioxygen-Bridged Porphyrin Dimers with Unusual Molecular Geometries. X-Ray Crystal Structures of {(μ-OH)3[Zr(OEP)]2}(7,8-C2B9H12) and (μ-O)(μ-OH)2[Zr(TPP)]2
Authors: Kim Hee-Joon , Whang Dongmok , Do Youngkyu , Kim Kimoon 
Published: April 2006

Abstract
The X-ray structures of the title complexes revealed that the two zirconium porphyrin moieties are joined either by three bridging hydroxo ligands or by one oxo and two hydroxo ligands. In both structures, the two porphyrin macrocycles are perfectly or nearly eclipsed and concomitantly one of the Zr-O bonds eclipses one of the Zr-N bonds. Such unprecedented eclipsed conformation found in both structures strongly suggests that it is stabilized by dπ-pπ interactions between Zr and O and N atoms despite the unfavorable steric interactions.
Synthesis of ortho-Acylbenzylboronates via Cross-Coupling Reaction of (Dialkoxyboryl)methylzinc Reagents with Haloarenes. A Stable ortho-Quinodimethane Precursor
Authors: Kanai Gen , Miyaura Norio , Suzuki Akira 
Published: April 2006

Abstract
The cross-coupling reaction of IZnCH2B(OCMe2) with iodoarenes in the presence of PdCl2(PPh3)2 produces the corresponding benzylic boronates in high yields. Among them, the benzylic boronates having an acyl group at the ortho position readily undergo the 1,5-rearrangement to the carbonyl oxygen producing the o-quinodimethane derivatives under thermal or photochemical conditions. The reaction provides benzo-fused cycloalkanes by trapping with dienophiles.
Structure of Nonplanar Octabromotetraphenyl Porphyrin and Kinetics of Rapid Metalation Reactions
Authors: Bhyrappa Puttaih , Nethaji Munirathinam , Krishnan Varadachari 
Published: April 2006

Abstract
Octabromotetraphenylporphyrin adopts a severe saddle-shaped distorted structure owing to the steric crowding of heavy bromine substituents. The rate enhancement of porphyrin metalation reaction is primarily due to the nonplanarity of the ring while the electronic effect diminishes the affinity of the porphyrin towards metal ions.
Synthesis of π-Conjugated Soluble Poly(aryleneethynylene) Type Polymers and Their Properties
Authors: Takagi Masakazu , Kizu Kenichi , Miyazaki Yuichi , Maruyama Tsukasa , Kubota Kenji , Yamamoto Takakazu 
Published: April 2006

Abstract
Pd-catalyzed coupling reactions with dihaloaromatic compounds X-Ar-X and diethynylaromatic compounds HC≡C-Ar′-C≡CH give new soluble π-conjugated polymers when Ar and/or Ar′ group is pyridine-2,5-diyl or has a long chain alkyl substituent.
Iodo-Ligand Substitution of [Pd(pp3)I]+ (pp3 = Tris(2-diphenylphosphinoethyl)phosphine) by Trimethylphosphite. The First Proposition of the Associative Ligand-Substitution Mechanism of Trigonal-Bipyramidal Five-Coordinate Palladium(II) Complex
Authors: Aizawa Sen-ichi , Funahashi Shigenobu 
Published: April 2006

Abstract
The kinetic investigation for the iodo-ligand substitution of [Pd(pp3)I]+ (pp3 = tris(2-diphenylphosphinoethyl)phosphine) by trimethylphosphite in CDCl3 has been performed by 31p NMR spectroscopy. The trigonal-bipyramidal structure of the reactant and product has been confirmed by X-ray analysis and 31p NMR spectra. The associative mode in the activation process is first proposed for the trigonal-bipyramidal palladium(II) complexes.
Ortho-Phenylenedizinc(II) Compounds Ultrasound-Promoted Synthesis from o-Diiodobenzene and Zinc Powder and Its Synthetic Application
Authors: Takagi Kentaro , Shimoishi Yasuaki , Sasaki Ken 
Published: April 2006

Abstract
A facile and efficient synthetic procedure of o-phenylenedizinc(II) compound from o-diiodobenzene and zinc powder under the irradiation of ultrasound is reported. The compound was proved to be a unique reagent supplying o-phenylenedianion of high chemoselectivity. Symmetrically 1,2-diaryl or diaroyl substituted benezenes were obtained in good yields by Pd(0)-catalyzed cross-coupling of the compound with aryl halides or acyl halides.
Photosensitized Two-electron Reduction of Viologen and the Reactivity of the Neutral Viologen
Authors: Park Joon Woo , Kim Jung Ha , Hwang Book Kee , Park Kwanghee Koh 
Published: April 2006

Abstract
The initially formed viologen radical cation (V•+) is further reduced to yield neutral viologen (V°) by Ru(bpy)32+ sensitized photochemical reduction. By the reactions with water, 75–80% of V° is reoxidized to V+ and the remainder is destroyed. The decreasing order of the reactivity is V° in the absence of β-cyclodextrin (β-CD) &gt; V° in the presence of β-CD &gt; V° covalently bound to β-CD.
Synthesis of 3-(1-Adamantyl)pyrazole and 3,5-Di(1-adamantyl)pyrazole in a Microwave Oven
Authors: Forfar Isabelle , Cabildo Pilar , Claramunt Rosa María , Elguero José 
Published: April 2006

Abstract
An extraordinary inversion of the regioselectivity in the reaction of C-adamantylation of pyrazoles by 1-bromoadamantane was observed when the autoclave vessel was replaced by a microwave oven. In these last conditions mono and disubstituted 3(5)-(1-adamantyl) pyrazoles were obtained.
Remarkable Salt Effects in the Highly Enhanced Enantioselective Hydrolysis of Amino Acid Esters with the Active Tripeptide in the Vesicular System
Authors: Goto Koichi , Imamura Chikara , Yamamoto Shinichi , Matsumoto Yoko , Ueoka Ryuichi 
Published: April 2006

Abstract
The remarkably high enantioselectivity (kLa,obsd/kDa,obsd = 67) was attained along with the large rate-enhancement of the L-form substrate for the hydrolytic cleavage of N-dodecanoyl-D(L)-Phe-PNP by controlling the ionic strength ([KCl] = 0.03 M, 1 M = 1 mol dm−3) in the vesicular system.
An FTIR Study of the Species Adsorbed on a Rh/Al2O3 Catalyst in the Selective Reduction of NO by Propylene
Authors: Bamwenda Gratian R , Obuchi Akira , Ogata Atsushi , Mizuno Koichi 
Published: April 2006

Abstract
An in situ FTIR study of the reduction of NO by propylene in O2 has shown that the reaction on the Rh/Al2O3 surface at 623 K leads to the formation of IR bands assigned to adsorbed hydrocarbons, -NCO, -CN, -NO+, -CO32− and CO2 species. The intensity of the bands depends on the reaction time and the presence or absence of the individual reactants.
Time-resolved Infrared Spectroscopic Diagnosis of a Bimolecular Chemical Reaction in Room Temperature Solution. The CCl3 Radical Produced from Photoexcited trans-Stilbene and Carbon Tetrachloride
Authors: Iwata Koichi , Kataoka Shuichi , Hamaguchi Hiro-o 
Published: April 2006

Abstract
The newly found photochemical reaction between trans-stilbene and carbon tetrachloride was examined with time-resolved infrared spectroscopy. On the photoexcitation of trans-stilbene in a carbon tetrachloride solution at room temperature, an intense infrared band was observed at 896 cm−1. This band is identified as a band from the trichloromethyl (CCl3) radical. It has been clarified that photoexcited trans-stilbene abstracts hydrogen from carbon tetrachloride to generate the CCl3 radical.
An ab Initio MO Study on Gas-Phase Adsorptive Interactions of Aromatic Compounds onto the Surface of Silica Gel
Authors: Suzuki Tetsuo , Tamon Hajime , Okazaki Morio 
Published: April 2006

Abstract
Microscopic features of gas-phase adsorption phenomena of a few aromatic compounds on the surface of silica gel have been investigated by ab initio molecular orbital (MO) calculations. The interaction energies and the structures of the adsorbate-adsorbent systems have been discussed. It has been found that interactions between the substituent groups of the aromatic compounds and silanol groups of silica gel contribute much to the adsorption.
High-Pressure Promoted and Silica Gel Catalyzed Aminolysis of Epoxides with Glycine Esters
Authors: Kotsuki Hiyoshizo , Shimanouchi Tomoyasu , Teraguchi Masahiro , Kataoka Masanori , Tatsukawa Akira , Nishizawa Hitoshi 
Published: April 2006

Abstract
A variety of epoxides are efficiently reacted with tert-butyl glycinates under high pressure conditions or by supporting on silica gel to afford the corresponding N-(β-hydroxyalkyl)glycine esters.
Oxalate Formation in Electrochemical CO2 Reduction Catalyzed by Rhodium-Sulfur Cluster
Authors: Kushi Yoshinori , Nagao Hirotaka , Nishioka Takanori , Isobe Kiyoshi , Tanaka Koji 
Published: April 2006

Abstract
Electrochemical reduction of CO2 catalyzed by a triangular rhodium complex [(RhCp*)3(μ3-S)2]2+ selectively produced formate and oxalate in the presence of Bu4NBF4 and LiBF4, respectively, under the controlled potential electrolysis at −1.50 V (vs. SCE) in CO2-saturated CH3CN. A solution IR spectrum evidenced the adduct formation between [(RhCp*)3(μ3-S)2]0 and CO2 as the possible precursor for the oxalate formation.
Photoluminescence of Layered Potassium Niobates (K4Nb6O17 and KNb3O8) and Effects of Hydration and H+-exchange on the Luminescence Properties
Authors: Kudo Akihiko , Sakata Tadayoshi 
Published: April 2006

Abstract
KNb3O8 showed blue luminescence of 450 nm at 300 K. The emission spectra of K4Nb6O17 and KNb3O8 at 77 K were red-shifted by H2O intercalation and H+-exchange, indicating that the photochemical properties of these hosts were changed with interlayer conditions.
Novel Preparation of Polyaniline Film from Poly(anthranilic acid) as a Precursor
Authors: Toshima Naoki , Yan Hu , Gotoh Yaeko , Ishiwatari Mariko 
Published: April 2006

Abstract
Poly(anthranilic acid), prepared by oxidative polymerization of anthranilic acid with ammonium peroxodisulfate, is soluble in N-methyl-2-pyrrolidone. The casting of the resulting solution forms a smooth film of poly(anthranilic acid). Heat treatment of the poly(anthranilic acid) film at about 240 °C produces a polyaniline film accompanying the elimination of carbon dioxide, which can provide a new method of preparation of a polyaniline film from the precursor.
Essential Role of Acidity in the Catalytic Reduction of Nitrogen Monoxide by Methane in the Presence of Oxygen over Palladium-Loaded Zeolites
Authors: Nishizaka Yukiko , Misono Makoto 
Published: April 2006

Abstract
It has been demonstrated that the protonic acidity is essential for the reduction of nitrogen monoxide by methane over Pd ion-exchanged H-ZSM-5 (Pd/HZ), by the comparison of the reaction with that over Pd ion-exchanged Na-ZSM-5 (Pd/NaZ), having similar dispersion of palladium. It was further shown that the difference between the active Pd/HZ and the inactive Pd/NaZ is present in the reaction between NO2 and CH4.
Selective Dimerization and Hydrogenation of Ethylene on Active Zirconium Oxide with Coordinatively Unsaturated Surface Sites
Authors: Moon Sang-Chul , Tsuji Kouji , Nomura Takaiki , Anpo Masakazu 
Published: April 2006

Abstract
The evacuation of the ZrO2 catalyst at higher temperatures led to the appearance of an abnormal absorption and photoluminescence due to the formation of coordinatively unsaturated surface sites. These active ZrO2 catalysts having coordinatively unsaturated surface sites exhibited a high catalytic activity for the selective dimerization of C2H4 to 2-C4H8. In the presence of H2 and C2H4, the formation of C4H10 was observed in place of 2-C4H8. The significant role of the coordinatively unsaturated surface sites in these reactions on the active ZrO2 catalyst has been clarified in detail for the first time.
Novel Generation, Characterization, and Trapping of 2-Methylene-3-cyclobutene-1-selones
Authors: Shimada Kazuaki , Akimoto Satoru , Takikawa Yuji , Kabuto Chizuko 
Published: April 2006

Abstract
Heating of alkynyl propargyl selenides afforded a stereoisomeric mixture of 5,10-diselenadispiro[3.1.3.1]deca-1,7-dienes. The 1,3-diselenetane rings of the products caused cycloreversion by heating to generate 2-methylene-3-cyclobutene-1-selones and the selones were trapped with diene to give [4+2] cycloadducts.
An Improved Purification Method for the Rapid Synthesis of High Purity Fluorobutyrophenone Neuroleptics from Nitro and Chloro Precursors Suitable for PET Study
Authors: Hashizume Kazunari , Hashimoto Naoto , Cork David G , Miyake Yoshihiro 
Published: April 2006

Abstract
A rapid micro-scale synthesis of fluorinated neuroleptics with extremely high chemical purity was accomplished using a new single column reverse-phase HPLC purification procedure that employs a strongly alkaline eluent to clearly separate F-labeled compounds from the large excess of nitro or chloro precursor. The method is applicable to the production of 18F-labeled positron emission tomography (PET) tracers with high specific activity.
Precise Discrimination between Butyl and Pentyl Groups in Molecular Aggregates
Authors: Endo Tadashi , Isago Takashi , Gohara Hideshi , Watanabe Susumu , Yazawa Takashi 
Published: April 2006

Abstract
In oxidation of a pair of associating thiols, one with a straight-chain alkyl or a cyclic hydrocarbon group and the other with a butyl or pentyl group, it has been shown that a butyl group can be distinguished accurately from a pentyl group by a cyclopentyl group in aqueous ethanol.
Reductive Conversion of Chlorodifluoromethylbenzene with Samarium(II) Diiodide
Authors: Yoshida Masato , Suzuki Daiki , Iyoda Masahiko 
Published: April 2006

Abstract
PhCF2Cl suffered readily one-electron reduction with SmI2 to give PhCF2 radical and chloride ion. The resulting PhCF2 radical was further reduced with SmI2 to PhCF2SmI2 which reacted with electrophile such as Me3SiCl. The initially formed PhCF2 radical could be trapped by olefin or acetylene before it was reduced to PhCF2SmI2.
New Type of Cyclodextrin Sandwiched Porphyrin
Authors: Kuroda Yasuhisa , Egawa Yuichiro , Seshimo Hidenori , Ogoshi Hisanobu 
Published: April 2006

Abstract
A porphyrin having two molecules of 2,3,6-permethyl-β-cyclodextrin was synthesized. The starting materials employed were the αβαβ atoropisomer or meso-tetrakis(o-aminophenyl)porphyrin and the diacidchloride of A,D-dicarboxyl derivative of 2,3,6-permethyl-β-cyclodextrin. As expected the product contained two isomers which were isolated by HPLC.
Stereoselective Photoinduced Electron Transfer of Zinc Myoglobin with Optically Active Viologens
Authors: Tsukahara Keiichi , Kimura Chieko , Kaneko Junko , Hara Tomoko 
Published: April 2006

Abstract
The excited triplet state of zinc myoglobin was preferentially quenched by (S,S)-isomers of optically active viologens, 1,1′-bis(1-phenylethylcarbamoylmethyl)-4,4′-bipyridimum (OAV2+) and 1,1′-bis(1-(1-naphthyl)ethylcarbamoylmethyl)-4,4′-bipyridinium (NOAV2+) ions: kq((S,S)-)/kq((R,R)-) = 1.5 for NOAV2+ and 1.3 for OAV2+ at 25 °C and an ionic strength of 0.02 mol dm−3.
Standardized Bending and Breaking Test for the Normal and Osteoporotic Metaphyseal Tibias of the Rat: Effect of Estradiol, Testosterone, and Raloxifene
Authors: Stürmer Ewa K , Seidlová-Wuttke Dana , Sehmisch Stephan , Rack Thomas , Wille Joern , Frosch Karl H , Wuttke Wolfgang , Stürmer Klaus M 
Published: April 2006

Abstract
The fracture of bone plays a key role in osteoporosis. BMD measurement, however, is only an indirect parameter of this phenomenon. We therefore developed a highly sensitive three-point bending test for the metaphyseal tibias in rats to evaluate stiffness and strength. This was validated in a right-left comparison and a bioassay with soy-free food, estradiol, raloxifene, and testosterone in orchidectomized rats.
Introduction: Osteoporosis becomes manifest predominantly in the metaphyseal rat tibia. The anti-osteoporotic character of substances should, therefore, be tested (mechanically) in this bone area.
Materials and Methods: We evaluated a new three-point bending test for the metaphyseal tibia in rats in a right-left trial. In an animal experiment, we studied the change of bone quality under estradiol (E)-, raloxifene (R)-, and testosterone (T)-supplemented food and compared it with trabecular BMD (qCT).
Results: In the right-left comparison, the mean difference between the metaphyseal loads of both tibias in 37 rats was 8.43% for the maximum load (Fmax) and 6.46% for the failure load (fL). These results show the high reproducibility of the test, because they are close to the usual intraindividual difference of the two extremities. In a second experiment, four groups of 11 3-month-old male orchidectomized rats were fed with soy-free food only (C) or with the additives E, T, or R for 12 weeks. E and R were similar for Fmax and fL. There were significant differences in the stiffness (E = 406.92 N/mm versus R = 332.08 N/mm), the yield load (yL; E = 99.17 N versus R = 83.33 N), and the ratio between yL and Fmax (E = 86.33% versus R = 76.37%). T was similar to the controls concerning Fmax, fL, and stiffness. There were significant differences in yL (T = 49.00N versus C = 39.5N) and the ratio between yL and Fmax (T = 64.28% versus C = 51.28%).
Conclusions: Estradiol is superior to raloxifene concerning stiffness and yield load, and both are superior to testosterone. We conclude that the described three-point bending test for the metaphyseal tibia is a highly sensitive method to study hormones and substances with regard to their osteoprotective character. The precision and the low SD of the presented results are superior to the data from qCT and the calculated index of stiffness (SSI).
Immunocompetent Properties of Human Osteoblasts: Interactions With T Lymphocytes
Authors: Stanley Katherine T , VanDort Christa , Motyl Christopher , Endres Judith , Fox David A 
Published: April 2006

Abstract
We sought to determine whether osteoblasts (OBs) can serve as accessory cells (ACs) for T-cell activation and whether T cells directly activate OB production of IL-6, using primary human OBs (NHOst), the transformed fetal osteoblast line hFOB1.19, and an osteosarcoma line SaOS-2. Robust, bidirectional activating interactions were shown using each of these three human ostoblast lines.
Introduction: Osteoblasts (OBs) could come into contact with lymphocytes during inflammatory joint destruction and fracture repair.
Materials and Methods: We used several in vitro assays to assess the ability of T cells and OBs to interact in the generation of immune and inflammatory responses.
Results: By flow cytometry, three OB cell lines all were found to express ligands for T-cell co-stimulation. The integrin ligand CD54/ICAM-1 was constitutively expressed by hFOB1.19 and NHOst and was upregulated on SaOS-2 by IFN-γ. MHC Class II was upregulated on all three lines by IFN-γ. CD166/ALCAM, a ligand of the T-cell molecule CD6, was constitutively expressed on all three lines. A second putative CD6 ligand designated 3A11 was expressed on hFOB1.19 and NHOst, but not consistently on SaOS-2. The ectoenzyme CD26 (dipeptidyl peptidase IV) was expressed on hFOB1.19 and NHOst, but not on SaOS-2. All three cell lines presented superantigen to T cells, especially after treatment with IFN-γ. Superantigen presentation was inhibited by antibodies to the leukocyte integrin CD11a/CD18 (LFA-1), MHC Class II, and CD54/ICAM-1. T cells, particularly when cytokine activated for 7 days before co-culture, stimulated all three osteoblast lines to produce interleukin (IL)-6, and this effect was boosted when IL-17 was added to the co-cultures with either resting T cells or cytokine-activated T cells.
Conclusions: Bidirectional activating interactions are readily shown between human T cells and several types of human OBs. The expression by OBs of ligands for the T cell-specific molecule CD6, as well as other molecules involved in immune interactions, strongly suggests that such in vitro interactions are representative of physiologic or pathologic events that occur in vivo.