bluuebunny/crossref_metadata_2025_split huggingface dataset:
Specialist training in Fiji: Why do graduates migrate, and why do they remain? A qualitative study
Authors: Oman Kimberly M , Moulds Robert , Usher Kim 
Published: February 2009

Abstract

Background
Specialist training was established in the late 1990s at the Fiji School of Medicine. Losses of graduates to overseas migration and to the local private sector prompted us to explore the reasons for these losses from the Fiji public workforce.

Methods
Data were collected on the whereabouts and highest educational attainments of the 66 Fiji doctors who had undertaken specialist training to at least the diploma level between 1997 and 2004. Semistructured interviews focusing on career decisions were carried out with 36 of these doctors, who were purposively sampled to include overseas migrants, temporary overseas trainees, local private practitioners and public sector doctors.

Results
120 doctors undertook specialist training to at least the diploma level between 1997 and 2004; 66 of the graduates were Fiji citizens or permanent residents; 54 originated from other countries in the region. Among Fiji graduates, 42 completed a diploma and 24 had either completed (21) or were enrolled (3) in a master's programme. Thirty-two (48.5%) were working in the public sectors, four (6.0%) were temporarily training overseas, 30.3% had migrated overseas and the remainder were mostly in local private practice. Indo-Fijian ethnicity and non-completion of full specialist training were associated with lower retention in the public sectors, while gender had little impact. Decisions to leave the public sectors were complex, with concerns about political instability and family welfare predominating for overseas migrants, while working conditions not conducive to family life or frustrations with career progression predominated for local private practitioners. Doctors remaining in the public sectors reported many satisfying aspects to their work despite frustrations, though 40% had seriously considered resigning from the public service and 60% were unhappy with their career progression.

Conclusion
Overall, this study provides some support for the view that local or regional postgraduate training may increase retention of doctors. Attention to career pathways and other sources of frustration, in addition to encouragement to complete training, should increase the likelihood of such programmes' reaching their full potentials.
Walking, running and the evolution of short toes in humans
Authors: Rolian Campbell , Lieberman Daniel E. , Hamill Joseph , Scott John W. , Werbel William 
Published: February 2009

SUMMARYThe phalangeal portion of the forefoot is extremely short relative to body mass in humans. This derived pedal proportion is thought to have evolved in the context of committed bipedalism, but the benefits of shorter toes for walking and/or running have not been tested previously. Here, we propose a biomechanical model of toe function in bipedal locomotion that suggests that shorter pedal phalanges improve locomotor performance by decreasing digital flexor force production and mechanical work, which might ultimately reduce the metabolic cost of flexor force production during bipedal locomotion. We tested this model using kinematic, force and plantar pressure data collected from a human sample representing normal variation in toe length (N=25). The effect of toe length on peak digital flexor forces, impulses and work outputs was evaluated during barefoot walking and running using partial correlations and multiple regression analysis, controlling for the effects of body mass,whole-foot and phalangeal contact times and toe-out angle. Our results suggest that there is no significant increase in digital flexor output associated with longer toes in walking. In running, however, multiple regression analyses based on the sample suggest that increasing average relative toe length by as little as 20% doubles peak digital flexor impulses and mechanical work,probably also increasing the metabolic cost of generating these forces. The increased mechanical cost associated with long toes in running suggests that modern human forefoot proportions might have been selected for in the context of the evolution of endurance running.
Phototropic growth in a reef flat acroporid branching coral species
Authors: Kaniewska Paulina , Campbell Paul R. , Fine Maoz , Hoegh-Guldberg Ove 
Published: February 2009

SUMMARY
Many terrestrial plants form complex morphological structures and will alter these growth patterns in response to light direction. Similarly reef building corals have high morphological variation across coral families, with many species also displaying phenotypic plasticity across environmental gradients. In particular, the colony geometry in branching corals is altered by the frequency, location and direction of branch initiation and growth. This study demonstrates that for the branching species Acropora pulchra,light plays a key role in axial polyp differentiation and therefore axial corallite development – the basis for new branch formation. A. pulchra branches exhibited a directional growth response, with axial corallites only developing when light was available, and towards the incident light. Field experimentation revealed that there was a light intensity threshold of 45 μmol m–2 s–1, below which axial corallites would not develop and this response was blue light(408–508 nm) dependent. There was a twofold increase in axial corallite growth above this light intensity threshold and a fourfold increase in axial corallite growth under the blue light treatment. These features of coral branch growth are highly reminiscent of the initiation of phototropic branch growth in terrestrial plants, which is directed by the blue light component of sunlight.
The relationships between muscle, external, internal and joint mechanical work during normal walking
Authors: Sasaki Kotaro , Neptune Richard R. , Kautz Steven A. 
Published: February 2009

SUMMARY
Muscle mechanical work is an important biomechanical quantity in human movement analyses and has been estimated using different quantities including external, internal and joint work. The goal of this study was to investigate the relationships between these traditionally used estimates of mechanical work in human walking and to assess whether they can be used as accurate estimates of musculotendon and/or muscle fiber work. A muscle-actuated forward dynamics walking simulation was generated to quantify each of the mechanical work measures. Total joint work (i.e. the time integral of absolute joint power over a full gait cycle) was found to underestimate total musculotendon work due to agonist–antagonist co-contractions, despite the effect of biarticular muscle work and passive joint work, which acted to decrease the underestimation. We did find that when the net passive joint work over the gait cycle is negligible, net joint work (i.e. the time integral of net joint power) was comparable to the net musculotendon work (and net muscle fiber work because net tendon work is zero over a complete gait cycle). Thus, during walking conditions when passive joint work is negligible, net joint work may be used as an estimate of net muscle work. Neither total external nor total internal work (nor their sum) provided a reasonable estimate of total musculotendon work. We conclude that joint work is limited in its ability to estimate musculotendon work, and that external and internal work should not be used as an estimation of musculotendon work.
Continuous light affects mineralization and delays osteoid incorporation in vertebral bone of Atlantic salmon (Salmo salar L.)
Authors: Wargelius Anna , Fjelldal Per Gunnar , Nordgarden Ulla , Hansen Tom 
Published: February 2009

SUMMARY
In order to study the effects of photoperiod on fish bone, Atlantic salmon(Salmo salar L.) were exposed to two light regimes (natural and continuous light) from January until June. During the experimental period,several parameters related to the inorganic (minerals) and organic (osteoid)phases were measured. Changes in the organic phase were related to mechanical strength (yield-load) and the expression of the genes sonic hedgehog(shh) and collagen type I alpha 2 (col I). Co-variation between yield-load and the expression of both shh and col I were detected in both groups. It was also shown that fish on the continuous light regime had delayed activation of osteoid incorporation. Mineralization properties were measured with stiffness, mineral incorporation per day and expression of alkaline phosphatase (alp) and matrix Gla protein (mgp). Stiffness, mineral incorporation and gene expression followed the same trend in both light groups in late spring, whereas an increase in the expression of mgp and alpwas detected in April, followed by significantly higher stiffness at last sampling in both light groups. These results indicate that constant light affects mineralization and delays osteoid incorporation in Atlantic salmon during the spring. However, in this experiment light treatment did not promote the development of vertebral deformities. Our results also suggest that shh can be used as a marker of osteoblast proliferation and col I a marker of osteoid incorporation, and that both alp and mgp expression could be associated with a rapid increase in mineralization in Atlantic salmon vertebrae.
Using omeprazole to link the components of the post-prandial alkaline tide in the spiny dogfish,Squalus acanthias
Authors: Wood Chris M. , Schultz Aaron G. , Munger R. Stephen , Walsh Patrick J. 
Published: February 2009

SUMMARYAfter a meal, dogfish exhibit a metabolic alkalosis in the bloodstream and a marked excretion of basic equivalents across the gills to the external seawater. We used the H+, K+-ATPase pump inhibitor omeprazole to determine whether these post-prandial alkaline tide events were linked to secretion of H+ (accompanied by Cl–) in the stomach. Sharks were fitted with indwelling stomach tubes for pretreatment with omeprazole (five doses of 5 mg omeprazole per kilogram over 48 h) or comparable volumes of vehicle (saline containing 2% DMSO) and for sampling of gastric chyme. Fish were then fed an involuntary meal by means of the stomach tube consisting of minced flatfish muscle (2% of body mass) suspended in saline (4% of body mass total volume). Omeprazole pre-treatment delayed the post-prandial acidification of the gastric chyme, slowed the rise in Cl– concentration of the chyme and altered the patterns of other ions, indicating inhibition of H+ and accompanying Cl– secretion. Omeprazole also greatly attenuated the rise in arterial pH and bicarbonate concentrations and reduced the net excretion of basic equivalents to the water by 56% over 48 h. Arterial blood CO2pressure (PaCO2) and plasma ions were not substantially altered. These results indicate that elevated gastric H+ secretion (as HCl) in the digestive process is the major cause of the systemic metabolic alkalosis and the accompanying rise in base excretion across the gills that constitute the alkaline tide in the dogfish.
Wave energy and the upper depth limit distribution of Posidonia oceanica
Authors: Infantes Eduardo , Terrados Jorge , Orfila Alejandro , Cañellas Bartomeu , Álvarez-Ellacuria Amaya 
Published: February 2009

Abstract
It is widely accepted that light availability sets the lower limit of seagrass bathymetric distribution, while the upper limit depends on the level of disturbance by currents and waves. The establishment of light requirements for seagrass growth has been a major focus of research in marine ecology, and different quantitative models provide predictions for seagrass lower depth limits. In contrast, the influence of energy levels on the establishment, growth, and maintenance of seagrasses has received less attention, and to date there are no quantitative models predicting the evolution of seagrasses as a function of hydrodynamics at a large scale level. Hence, it is not possible to predict either the upper depth limit of the distribution of seagrasses or the effects that different energy regimes will have on these limits. The aim of this work is to provide a comprehensible methodology for obtaining quantitative knowledge and predictive capacity for estimating the upper depth limit of seagrasses as a response to wave energy dissipated on the seafloor. The methodology has been applied using wave data from 1958 to 2001 in order to obtain the mean wave climate in deep water seaward from an open sandy beach in the Balearic Islands, western Mediterranean Sea where the seagrass Posidonia oceanica forms an extensive meadow. Mean wave conditions were propagated to the shore using a two-dimensional parabolic model over the detailed bathymetry. The resulting hydrodynamics were correlated with bottom type and the distribution of P. oceanica. Results showed a predicted near-bottom orbital velocity of between 38 and 42 cm s-1 as a determinant of the upper depth limit of P. oceanica. This work shows the importance of interdisciplinary effort in ecological modeling and, in particular, the need for hydrodynamical studies to elucidate the distribution of seagrasses in shallow depths. Moreover, the use of predictive models would permit evaluation of the effects of coastal activities (construction of ports, artificial reefs, beach nutrient-input, dredging) on benthic ecosystems.
Investigating the humor of gelotophobes: Does feeling ridiculous equal being humorless?
Authors: Ruch Willibald , Beermann Ursula , Proyer René T. 
Published: February 2009

AbstractTitze (Humor and Health Journal 5:1–11, 1996) concluded from individual case studies that gelotophobes do not experience humor and laughter as a shared enjoyment but rather as a threat. Two studies examined whether gelotophobes are less humorous in general or whether this is true only for certain components of humor. In study I, three samples (N = 120 and 70 students; N = 169 adults) filled in the GELOPH〈46〉 along with several humor instruments (i.e., 3 WD, CHS, HBQD, HSQ, HUWO, STCI-T〈60〉). Results showed that gelotophobes are less cheerful and characterize their humor style as inept, socially cold, and mean-spirited. They report less frequent use of humor as a means for coping and indulge less often in self-enhancing and social humor. Appreciation of incongruity-resolution humor and nonsense humor (but not sexual humor) was lower than for non-gelotophobes. Study II (N = 131 adults) focused on the relation between gelotophobia, gelotophilia, and katagelasticism and the ability to create humor (i.e., the CPPT). The ability to create humor is unrelated to gelotophobia, and tends to be positively correlated with gelotophilia and katagelasticism. Future studies should investigate why gelotophobes see their humor style as inept despite not lacking wit, and how their beliefs can be made more consistent with their abilities.
The fear of being laughed at among psychiatric patients
Authors: Forabosco Giovannantonio , Ruch Willibald , Nucera Pietro 
Published: February 2009

AbstractThe fear of being laughed at brings to the fore the problematic side of an otherwise very positive aspect of human experience. In the streamline of investigations analyzing the presence and characteristics of gelotophobia, a study focusing on psychiatric patients was carried out. The diagnoses were established according to the criteria of the DSM IV TR (American Psychiatric Association, Diagnostic and Statistical Manual of Mental Disorders (DSM), APA, 2000). Based both on clinical and empirical observations, the main hypothesis advanced was that using the Geloph〈15〉 scale, Ss with a psychiatric diagnosis would have higher mean scores than Normal Controls. An additional hypothesis was that intragroup differences were also expected among the various diagnostic categories. The main hypothesis was amply supported, and explanatory suggestions of the finding were proposed. Intragroup differences proved also to be significant. Patients with personality disorders and patients with schizophrenic disorders scored higher than Normal Controls and the other diagnostic groups. And also the number of years spent in psychiatric care resulted significantly associated with higher gelotophobia mean scores. From the present study, a circular, interactive relationship was confirmed between laughter and mental health, which can alternatively be highly positive or deeply negative.
Toward a Legal-Ethical Framework for Regulating Human Genetic Information in Vulnerable Populations: An Issue of Justice
Authors: de Ortúzar Maria Graciela 
Published: February 2009

AbstractThe main purpose of this work is to discuss the legal, psycho-social and ethical issues posed when handling genetic information in genomic research within developing countries. Following the method of “reflective equilibrium”(Rawls-Daniels) and from an interdisciplinary approach, I shall go through: (1) current normative laws concerning its regulation, advantages and limitations; (2) the psychosocial impact of genetics on health issues; and (3) the ethical grounds that should be taken into account in establishing the normative framework for the regulation of genetic information. In general terms, my opinion is that the ethical grounds of the normative framework regarding research with human beings cannot be formal or based exclusively on the law (e. g. “bureaucratisation of informed consent”). My suggestions is that a critical notion of real autonomy and material wellbeing of the moral person (following Doyal- Sen-Van Parijs) should be applied to justify the distributive principles implied in any research on human beings, in particular in genomic research (benefit sharing.)
A Review of the No Erosion Filter Test
Authors: Soroush Abbas , Shourijeh Piltan Tabatabaie 
Published: February 2009

Abstract
The no erosion filter (NEF) test is widely accepted as the most appropriate filtration test for the substantiation of suitable critical filters in embankment dams. No consistent standard method for NEF testing has been introduced; thus, various schemes have been implemented for performing NEF tests. This paper reviews critically the antecedent research on the NEF testing procedure. The cornerstone hypothesis of NEF testing and the evolution of the testing method are reviewed. The significance of different parameters encountered in the testing procedure and their relevance and importance in the judgment are elaborated. Practical guides for proper conduction of the NEF test are recommended throughout this paper.
Perceived Everyday Racism, Residential Segregation, and HIV Testing Among Patients at a Sexually Transmitted Disease Clinic
Authors: Ford Chandra L. , Daniel Mark , Earp Jo Anne L. , Kaufman Jay S. , Golin Carol E. , Miller William C. 
Published: February 2009

Objectives. More than one quarter of HIV-infected people are undiagnosed and therefore unaware of their HIV-positive status. Blacks are disproportionately infected. Although perceived racism influences their attitudes toward HIV prevention, how racism influences their behaviors is unknown. We sought to determine whether perceiving everyday racism and racial segregation influence Black HIV testing behavior. Methods. This was a clinic-based, multilevel study in a North Carolina city. Eligibility was limited to Blacks (N = 373) seeking sexually transmitted disease diagnosis or screening. We collected survey data, block group characteristics, and lab-confirmed HIV testing behavior. We estimated associations using logistic regression with generalized estimating equations. Results. More than 90% of the sample perceived racism, which was associated with higher odds of HIV testing (odds ratio = 1.64; 95% confidence interval = 1.07, 2.52), after control for residential segregation, and other covariates. Neither patient satisfaction nor mechanisms for coping with stress explained the association. Conclusions. Perceiving everyday racism is not inherently detrimental. Perceived racism may improve odds of early detection of HIV infection in this high-risk population. How segregation influences HIV testing behavior warrants further research.
Association Between HIV-1 RNA Level and CD4 Cell Count Among Untreated HIV-Infected Individuals
Authors: Lima Viviane D. , Fink Valeria , Yip Benita , Hogg Robert S. , Harrigan P. Richard , Montaner Julio S. G. 
Published: February 2009

Objectives. We examined the significance of plasma HIV-1 RNA levels (or viral load alone) in predicting CD4 cell decline in untreated HIV-infected individuals. Methods. Data were obtained from the British Columbia Centre for Excellence in HIV/AIDS. Participants included all residents who ever had a viral load determination in the province and who had never taken antiretroviral drugs (N = 890). We analyzed a total of 2074 viral load measurements and 2332 CD4 cell counts. Linear mixed-effects models were used to predict CD4 cell decline over time. Results. Longitudinal viral load was strongly associated with CD4 cell decline over time; an average of 1 log10 increase in viral load was associated with a 55-cell/mm3 decrease in CD4 cell count. Conclusions. Our results support the combined use of CD4 cell count and viral load as prognostic markers in HIV-infected individuals before the introduction of antiretroviral therapy.
Evaluation of methods for isolation of DNA for PCR based identification of pathogenic bacteria from pure cultures and water samples
Authors: Horáková K. , Mlejnková H. , Mlejnek P. 
Published: February 2009

Water Science and Technology 58(5), 995–999
Publisher's note. We regret that the version of this article used in production did not incorporate a number of corrections and clarifications. The corrected versions of the text are as given below.
Longitudinal Construct Validity of the GMFM-88 Total Score and Goal Total Score and the GMFM-66 Score in a 5-Year Follow-up Study
Authors: Lundkvist Josenby Annika , Jarnlo Gun-Britt , Gummesson Christina , Nordmark Eva 
Published: February 2009

BackgroundThe Gross Motor Function Measure (GMFM) is the instrument most commonly used to measure gross motor function in children with cerebral palsy (CP). Different scoring options have been developed, and their measurement properties have been assessed. Limited information is available regarding longitudinal construct validity.ObjectiveThe objective of this research was to study the longitudinal construct validity of 3 scoring options: the 88-item GMFM (GMFM-88) total, the GMFM-88 goal total, and the 66-item GMFM (GMFM-66).DesignA clinical measurement design was used in this study.MethodsForty-one children with CP diplegia who were undergoing selective dorsal rhizotomy (SDR) were monitored with the GMFM for 5 years. The mean age at SDR was 4.4 years (range=2.5–6.6). Two subgroups for gross motor function before surgery were created according to the Gross Motor Function Classification System (GMFCS): GMFCS levels I to III and GMFCS levels IV and V. This study included results obtained before SDR and at 6, 12, and 18 months and 3 and 5 years after SDR. The effect size (ES) and the standardized response mean (SRM) were calculated.ResultsAt 6 months postoperatively, ES and SRM values were small (≤0.5) for all GMFM scoring options. The GMFM-88 total and goal total scores showed large changes in ES values (range=0.8–0.9) and SRM values (range=0.9–1.3) at 12 months postoperatively, whereas the GMFM-66 scores showed lower ES values (range=0.3–0.4) and SRM values (range=0.7–0.8) for both subgroups. Later postoperatively, larger values for longitudinal construct validity were found. The ES and SRM values generally were lower for the GMFM-66 scores than for the GMFM-88 total and goal total scores.LimitationsAll children underwent an extensive intervention, and changes in gross motor function were expected.ConclusionAll 3 scoring options showed large longitudinal construct validity in the long-term follow-up. The GMFM-88 total and goal total scores revealed large changes in gross motor function earlier postoperatively than the GMFM-66 scores.