bluuebunny/crossref_metadata_2025_split huggingface dataset:
The National and Cultural Specifics of the Verbalization of the “Anti-Terrorism Measures” Concept Sphere in English and Russian Linguocultures
Authors: Vezner I. A. , Lisitsa I. V. 
Published: February 2025

Introduction. The method of cognitive-conceptual modeling is becoming increasingly important in analysing discursive phenomena and it allows to identify both universal and ethnocultural content of concept spheres as well as to characterize the linguistic means of their verbalization. The application of this method allows the authors of the paper to describe the means of discursive representation of the concept sphere ‘anti-terrorism measures’ in English and Russian linguocultures. The paper attempts to identify conceptually significant features of the configuration of the concept sphere under analysis.Methodology and sources. Conceptually significant features and the specifics of their configuration are examined as the verbal objectification of social interaction, influenced by a range of cultural factors. The linguistic material comprises handouts, guides, and manuals from websites, as well as anti-terrorism guides, manuals, and instructions placed in educational institutions and public transport in Novosibirsk. The authors employed such methods as information and semantic text analysis, cognitive-comparative modelling of the concept sphere, genre-discursive and comparative analyses.Results and discussion. The analysis identified the following fundamental concepts that objectify the concept sphere “anti-terrorism measures”: “a subject countering terrorist activity”, “a probable subject of terrorist activity”, “prescribed actions and measures to prevent a terrorist attack”, “probable actions of hostages”, “probable actions after a terrorist attack”. In the English linguoculture, the texts that can be attributed to strongly preventive genres of anti-terrorist discourse prevail. In Russian linguoculture, anti-terrorist materials mainly present the situations at a later stage of a terrorist attack; they are characterized by joint verbalization of the concepts ‘vertical integration’ and ‘centralization’.Conclusion. The research results indicate that the examined anti-terrorism materials possess a number of culturally determined conceptual features based on the following oppositions: “highly preventive – weakly preventive”, “horizontally integrated community – vertically integrated community”, and “decentralization – centralization”.
Implementation of Generative Artificial Intelligence in Sociological Research
Authors: Drach V. E. , Torkunova Yu. V. 
Published: February 2025

Introduction. This article discusses the use of generative artificial intelligence (GAI) in sociological research. The relevance of the topic is determined by the increasing interest in applying new technologies to enhance the efficiency and accuracy of research in social sciences. GAI provides new opportunities for data collection, processing, and analysis, which can significantly change traditional approaches in sociology.Methodology and sources. The research is based on an analysis of available publications and experimental data obtained during discussions with sociologists using GAI in their projects. The paper examines methodologies for generating surveys, processing respondents' answers, and analyzing big data using machine learning algorithms. The focus is on specific cases of GAI applications in sociological research, as well as examples of successful projects.Results and discussion. The results of the study demonstrate that the use of GAI allows for significantly accelerating the data processing process and enhancing the quality of the data. New patterns and trends in sociological research have been identified, enabling researchers to draw more accurate and justified conclusions. Ethical aspects related to the use of GAI are also discussed, such as issues of confidentiality and algorithmic bias.Conclusion. Generative artificial intelligence represents a powerful tool capable of transforming sociological research. Despite existing challenges, it opens new horizons for data collection and analysis, fostering a deeper understanding of social processes and phenomena. It is important to continue exploring the possibilities and limitations of GAI for the advancement of sociological science.
Prediction of Aerothermal Heating: From Numerical Simulations to Machine Learning Models
Authors: Wang Yuchao , Huang Yunzhe , Zhou Hongjie , Wang Yan , Ji Tingwei , Xie Fangfang 
Published: February 2025

High-speed aircraft experiences severe aerodynamic heating at high Mach numbers, requiring accurate prediction of aerothermal heating effects before designing thermal protection systems. With the rise of artificial intelligence and the potential of neural networks, data-driven methods for aerothermal heating prediction have gained significant attention. This study focuses on numerical simulations of aerothermal heating phenomena and explores machine learning applications in heat prediction. First, a two-dimensional cylinder case was simulated using the finite volume method with chemical non-equilibrium flow to understand flow characteristics and heat distribution. Subsequently, Two aerothermal heating datasets were established: the first varies Mach number from 7.0 to 11.9 under fixed freestream conditions, while the second combines Mach numbers (8.5–9.5) with varying temperatures (890 K, 901 K, 910 K) and pressures (460 Pa, 470 Pa, 476 Pa). And the influence of incoming flow conditions on shock waves, temperature fields, wall heat flux was analyzed. Finally, machine learning methods were applied to predict aerothermal heating properties. A multilayer perceptron (MLP) prediction model was established to predict wall heat flux, the reverse line from the stagnation point along the flow direction pressure and temperature, as well as the temperature and pressure fields. Additionally, a convolutional neural network (CNN) model was developed to accurately predict the temperature and pressure fields. While the MLP model demonstrates strong predictive accuracy for physical quantities along the cylinder surface and the reverse line from the stagnation point along the flow direction, the CNN model exhibits superior performance in predicting the entire flow field. Compared to the numerical simulation methods used, the established model can quickly predict the aerothermal environment of a two-dimensional cylinder, helping to shorten the design cycle of thermal protection systems.
A novel fluorescein sodium-based screening platform for the identification of sphingoid base-producing Wickerhamomyces ciferrii mutants
Authors: Kang Jun Su , Lee Seong-Rae , Lee Minju , Kim Eunha , Lee Pyung Cheon 
Published: February 2025

The efficient identification of microbial strains capable of producing rare sphingoid bases, such as sphingosine and sphinganine, is critical for advancing microbial fermentation processes and addressing increasing industrial demands. Wickerhamomyces ciferrii, a non-conventional yeast, naturally overproduces tetraacetyl phytosphingosine (TAPS); however, the production of other valuable sphingoid bases, including sphingosine, sphinganine, and triacetyl sphingosine, remains a key target. In this study, we developed a novel screening method utilizing fluorescein sodium, a selective fluorescent dye that specifically reacts with non-acetylated sphingoid bases—sphinganine, sphingosine, and phytosphingosine—while exhibiting no reactivity with TAPS. A mutant library of W. ciferrii was generated via gamma-ray mutagenesis and screened using fluorescence-activated cell sorting (FACS). Mutants exhibiting high fluorescence intensity, indicative of non-acetylated or partially acetylated sphingoid base production, were isolated through three rounds of sorting and further validated via HPLC analysis. This approach successfully identified three mutant strains: P41C3 (sphingosine-producing), M01_5 (sphinganine-producing), and P41E7 (triacetyl sphingosine-producing). Among them, the P41C3 mutant achieved a sphingosine titer of 36.7 mg/L during shake-flask cultivation, accompanied by a significant reduction in TAPS production, indicating a redirection of metabolic flux. This study demonstrates the utility of fluorescein sodium as a selective screening dye for sphingoid base-producing strains and establishes an effective platform for the metabolic engineering of W. ciferrii to enhance the production of industrially significant sphingolipids.
Automated requirements engineering framework for agile model-driven development
Authors: Umar Muhammad Aminu , Lano Kevin , Abubakar Abdullahi Kutiriko 
Published: February 2025

IntroductionAdvances in requirements engineering, driven by various paradigms and methodologies, have significantly influenced software development practices. The integration of agile methodologies and model-driven development (MDE) has become increasingly critical in modern software engineering. MDE emphasizes the use of models throughout the development process, necessitating structured approaches for handling requirements written in natural language.MethodsThis paper proposes an automated requirements engineering framework for agile model-driven development to enhance the formalization and analysis of textual requirements. The framework employs machine learning models to extract essential components from requirements specifications, focusing specifically on class diagrams. A comprehensive dataset of requirements specification problems was developed to train and validate the framework's effectiveness.ResultsThe framework was evaluated using comparative evaluation and two real-world experimental studies in the medical and information systems domains. The results demonstrated its applicability in diverse and complex software development environments, highlighting its ability to enhance requirements formalization.DiscussionThe findings contribute to the advancement of automated requirements engineering and agile model-driven development, reinforcing the role of machine learning in improving software requirements analysis. The framework's success underscores its potential for widespread adoption in software development practices.
Enhancing design skills in art and design education
Authors: Oo Tun Zaw , Kadyirov Timur , Kadyjrova Lyajsan , Józsa Krisztián 
Published: February 2025

IntroductionIn art and design education, design-based learning (DBL) is crucial for students’ design skills enhancement. Moreover, students’ motivation plays a significant role in their creative performance in design education. Therefore, this study aimed to explore the impact of students’ DBL and motivation on their design skills development in art and design education.MethodsNotably, 207 University students participated in the current experimental research. With the help of nonrandom sampling, the experimental group (102) and the control group (105) were divided. The experimental group was given the treatment with DBL and the control group with the traditional instructions.Results and discussionThe findings showed that experimental students who were treated by the DBL performed better in design skills assessment than those who were given traditional instructions. However, no gender difference was found in the analysis of covariance in the design skills assessment. Students’ motivation, such as intrinsic motivation, achievement motivation, and failure-avoidance motivation also have significant impacts on their design skills development. These research findings encouraged educators to be able to use the DBL technique in their design skills instructions.
Single-cell RNA-sequencing reveals cellular heterogeneity and immune microenvironment characteristics between ocular adnexal mucosa-associated lymphoid lymphoma and IgG4−related ophthalmic disease
Authors: Yang Yu , Wang Yujiao , Jin Xuelian , He Weimin 
Published: February 2025

IntroductionThe molecular pathogenesis of ocular adnexal mucosa-associated lymphoid tissue (MALT) lymphoma and IgG4-related ophthalmic disease (IgG4-ROD) remains incompletely understood. Differentiating between the two diseases is vital given that the diagnostic evaluation and treatment approaches can vary significantly; this difficulty in distinction is exacerbated by the absence of specific biomarkers. This study aimed to investigate the differences between these two diseases based on their cellular composition, transcriptional heterogeneity, and the immune microenvironment using single-cell RNA transcriptional sequencing (scRNA-seq) technology.MethodsWe collected orbital lacrimal gland region tissue samples from three patients with MALT lymphoma and another three with IgG4-ROD and performed single-cell sequencing experiments. Subsequently, we conducted bioinformatics analyses, including cell subpopulation segmentation and inter-group comparison, tumor cell identification, functional enrichment analysis, and pseudotime trajectory analysis. Furthermore, we analyzed the cellular communication between tumor B-cell and T-cell subsets within the immune microenvironment of MALT lymphoma tissues. We performed immunofluorescence assays to verify the co-expression of receptor-ligand pairs.ResultsA total of six major cell subpopulations were identified, with B-cells and T-cells being the predominant cell types. All B-cell subpopulations in MALT lymphomas are malignant, exhibiting significant intratumoral and intertumoral heterogeneity. Reclustering of the T-cell subpopulation identified five major T-cell subpopulations. Pseudotime analysis revealed that CD4+ naive T-cells in MALT lymphoma patients were highly likely to differentiate into follicular helper T-cells, whereas, in IgG4-ROD patients, CD4+ naive T-cells were highly likely to differentiate into regulatory T-cells. Intercellular communication analysis revealed that the CD27-CD70 immune checkpoint receptor−ligand pair and CXCL13-CXCR5 chemokine receptor−ligand pair were significantly upregulated between malignant B-cells and T-cells subpopulations.ConclusionThis study is the first to conduct a comparative single-cell transcriptome sequencing analysis of ocular adnexal MALT lymphoma and IgG4-ROD. Our results reveal the cellular composition, key pathways, and critical immune microenvironment implicated in the development of these two diseases. These findings provide important insights into the pathogenesis of these two diseases and highlight the differences between them.
Effect of dietary Clostridium butyricum supplementation on growth performance, immune function, and intestinal health of hybrid grouper (Epinephelus fuscoguttatus ♀ × Epinephelus lanceolatus ♂)
Authors: Chen Weijun , Song Tao , Li Dong , Chen Mingfan , Wang Pan , Ye Jidan 
Published: February 2025

IntroductionThe aim of this study is to investigate the effects of supplementing Clostridium butyricum (C. butyricum) on hybrid grouper (Epinephelus fuscoguttatus ♀ × Epinephelus lanceolatus ♂), with a particular focus on its impact on growth performance, blood composition, intestinal antioxidant capacity, gut microbiota, tight junction protein (ZO-1) expression, and inflammatory gene expression. The study seeks to uncover the potential health benefits of C. butyricum supplementation for hybrid grouper.MethodsThe experiment included four groups: a control group (CON) and three experimental groups, each supplemented with different strains of C. butyricum (KM, DZN, and CLH), with a concentration of 1 × 10⁷ colony-forming units per gram. These groups were designated as CB1 (KM), CB2 (DZN), and CB3 (CLH). The study evaluated growth performance, blood composition, intestinal antioxidant capacity, gut microbiota, ZO-1 protein expression, and inflammatory gene expression (IL-1β and Ikk-β).ResultThe results indicated that supplementation with C. butyricum had no significant effect on body weight gain (WG), feed efficiency (FE), or body composition. However, the CB3 group significantly increased the activity of superoxide dismutase (SOD) and glutathione peroxidase (GSH-Px) in the intestine, as well as the expression of ZO-1. In addition, the CB3 group significantly increased serum lysozyme (LZM) activity, complement 4 (C4) levels, and immunoglobulin M (IgM) concentration, while significantly reducing the expression of pro-inflammatory genes (IL-1β and Ikk-β). After supplementation with C. butyricum, the level of malondialdehyde (MDA) in the intestine was significantly lower than that in the control group, indicating a reduction in intestinal oxidative stress. Supplementation with C. butyricum also altered the composition of the gut microbiota, promoting the growth of beneficial bacteria and inhibiting pathogenic bacteria, thereby further enhancing ZO-1 expression and intestinal barrier function.DiscussionThis study suggests that supplementing C. butyricum has a significant immunomodulatory effect on hybrid grouper, enhancing serum immune parameters, alleviating intestinal inflammation and oxidative stress, and promoting intestinal health. Although no significant impact was observed on growth performance, the role of C. butyricum in improving intestinal barrier function and modulating the gut microbiota highlights its potential for enhancing fish health.
The impact of chronic diseases and lifestyle on sarcopenia risk in older adults: a population-based longitudinal study
Authors: Wei Wu-xiao , Mao Zhen-fang , Chen Meng-li , Meng Lian 
Published: February 2025

BackgroundSarcopenia, characterized by the gradual decline of muscle mass and strength, seriously affects the health and mobility of older adults. The purpose of this study is to investigate the risk factors for sarcopenia, particularly the relationship between chronic diseases and lifestyle factors in individuals aged 60 and over.MethodsThis study used data from the Longitudinal Study on Health and Retirement in China (CHARLS) collected in 2011 and 2015. All eligible participants were classified according to the standards established by the Asian Sarcopenia Working Group in 2019. The evaluation of sarcopenia was based on a comprehensive score across five dimensions: strength, assistance in walking, rise from a chair, climb stairs, and falls. A multivariate logistic regression model was employed to explore the risk factors for sarcopenia.ResultsThe risk of sarcopenia is significantly influenced by multiple factors. Key findings include the association between past drinking and an increased risk of sarcopenia (HR = 2.198, 95% CI: 1.072–4.560, p &lt; 0.05), indicating that individuals with a history of drinking have more than twice the risk of sarcopenia compared to non-drinkers. Chronic diseases such as stroke were also associated with a significantly elevated risk (HR = 3.137, 95% CI: 1.128–8.721, p &lt; 0.05). Conversely, participation in social activities significantly reduced the risk of sarcopenia (HR = 0.482, 95% CI: 0.265–0.876, p &lt; 0.05). A three-piece spline regression model revealed a nonlinear relationship between physical activity and the risk of sarcopenia, characterized by an initial decline in risk followed by an increase as physical activity levels rose. Moderate-intensity physical activity reduced the risk of sarcopenia by approximately 35% (HR ≈ 0.65). However, high-intensity physical activity led to a rebound in risk, increasing the likelihood of sarcopenia relative to moderate activity. Similarly, adequate sleep duration was associated with a reduced risk of sarcopenia, whereas excessive sleep counteracted this benefit.ConclusionThe findings underscore the critical role of lifestyle modifications and balanced physical activity in mitigating the risk of sarcopenia among older adults. Implementing targeted interventions for high-risk groups is essential to reduce the incidence of sarcopenia.
Citrate as a safe and effective alternative to heparin for catheter locking: a systematic review and meta-analysis of randomized controlled trials
Authors: Lai Binbin , Huang Weixing , Yu Hui , Chen Tingting , Gao Yimen , Wang Wei , Luo Hua 
Published: February 2025

BackgroundConsensus on the use of citrate vs.heparin for catheter locking remains elusive, with ongoing controversy. This meta-analysis investigates the efficacy and safety of citrate lock solutions compared to heparin lock solutions in preventing catheter-related complications.MethodsThe review process was conducted according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Two independent reviewers conducted literature searches based on preferred reporting items from systematic reviews and meta-analyses. PubMed, EMBASE, Medline, and the Cochrane Library were searched for studies comparing citrate and heparin in patients with catheter. Catheter-related bloodstream infection (CRBSI), catheter-related infection (CRI), exit-site infection (ESI), and adverse events were analyzed.ResultsThe meta-analysis included 17 randomized controlled trials (RCTs), encompassing 247,431 catheter-days, with 128,904 in the citrate group, and 118,527 in the heparin group. Citrate lock solutions significantly reduced the incidence of CRBSI compared to heparin (RR: 0.48, 95% CI: 0.31–0.73), particularly when combined with antibiotics or used at low concentrations. No significant differences were observed between the groups for CRI, ESI, catheter dysfunction, or local bleeding. Subgroup and sensitivity analyses addressed heterogeneity, confirming the robustness of the primary findings.ConclusionsCitrate lock solutions effectively prevent CRBSI without increasing systemic coagulation dysfunction or bleeding risk. Citrate lock solutions are a safe and effective alternative to heparin, especially when combined with antibiotics.Systematic review registrationhttps://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42024562511.
Person-centered workplace culture: insights from an inpatient department for older adults with chronic illnesses
Authors: Vareta Diana , Oliveira Célia , Ventura Filipa 
Published: February 2025

IntroductionAn aging population and the increasing prevalence of chronic conditions challenge healthcare systems in developed countries. In response, there is a growing emphasis on person-centered care, as advocated by the World Health Organization and integrated into national health strategies in countries such as the UK and Sweden. However, transitioning to person-centered care is a complex, long-term process shaped by organizational culture and care environments. These contextual factors play crucial roles in the development and sustainability of person-centered practice, significantly transforming the experiences of both older adults and staff.ObjectiveTo describe how workplace culture within an inpatient hospital department shapes person-centered care practices for older adults with chronic illnesses.MethodsA qualitative, descriptive, exploratory-observational study was performed. Data were collected through participant observation guided by the Workplace Culture Critical Analysis Tool®. In a deductive thematic content analysis, data patterns of meaning were identified. The themes were generated underpinned by the Person-Centered Practice Framework dimensions of prerequisites, the practice environment, and person-centered processes and their respective constructs.ResultsThemes related to all person-centered practice dimensions were identified. Task demands during shifts create tension between routine-oriented work and the holistic, individualized approach required for person-centeredness. The absence of systematic multiprofessional team meetings further exacerbates this issue, limiting collaborative decision-making and personalized care planning. The contrasts in some subthemes may be related to discrepancies in the care provided by different professionals.ConclusionThis study highlights the tension between routine-driven care and individualized approaches. Addressing identified challenges, such as formalizing multiprofessional meetings and enhancing reflective practices, is crucial for advancing person-centered care in this setting.