bluuebunny/crossref_metadata_2025_split huggingface dataset:
Weton Calculations as A Basis for Marriage Implementation (Case Study at Kandangmas Dawe Kudus)
Authors: Nafi' Muhamad Agus Yusrun 
Published: March 2024

<p>This research uses a qualitative method with an Islamic Law approach which examines basic norms, implementation of basic norms, and the impact of basic norms in calculating marriage weton at Kandangmas Dawe Kudus.. Research purposes This is to describe Many people do the calculation of weton in marriages in the Kandangmas Dawe Kudus community, but researchers also found people who don’t believe or ignore the calculation of weton births in marriage, this is motivated by family, community environment, strong religious beliefs and belief in qadha and qadar. Research result: The people of Kandangmas Dawe Kudus need a wise and wise attitude to pay attention to old values or traditions such as good weton calculations and accept new values that are better and more useful so that they remain in line with the times and the values of noble Islamic teachings. As long as it does not change the faith and contradict the teachings of Islam, such traditions can be implemented and developed. On the other hand, if it conflicts with the teachings of the Islamic religion, then the tradition must be abandoned.</p>
An in-silico approach to elucidate the pathways leading to primary osteoporosis: age-related vs. postmenopausal
Authors: Ruiz-Lozano Rocío , Calvo-Gallego José Luis , Pivonka Peter , McDonald Michelle , Martínez-Reina Javier 
Published: March 2024

Abstract

Numerical models of bone remodelling have traditionally been used to simulate bone loss in postmenopausal women and the response to drug treatments. These models simulate the menopausal estrogen decline by altering certain signalling pathways. However, they overlook the simultaneous effect that ageing can have on bone cells function and thus on bone loss. Considering ageing and estrogen decline together is important for designing osteoporosis treatments that can counteract one of the two factors.A previously developed bone remodelling model was adapted to consider the effect of ageing through: (1) decreased TGF-beta content within bone matrix; (2) increased sclerostin production by non-skeletal cells. Estrogen deficiency is simulated in three different ways: (a) increased RANKL expression; (b) decreased OPG production; (c) increased responsiveness of osteoclasts to RANKL. The effect of ageing was validated using clinical BMD data of vertebral trabecular bone from males. The joint effect of ageing and estrogen deficiency was validated using the corresponding clinical data in women.In ageing, the effect of increased sclerostin production is more important than the decrease in TGF-beta. The three mechanisms used to simulate the effect of estrogen deficiency yielded almost identical responses. The results show that early menopause leads to lower density in the fifth decade, but after the sixth decade density is almost independent of the age at menopause on average. Osteoporosis treatment with denosumab was also simulated, concluding that the treatment proves more necessary after 10 years since menopause or after age 60.
Mathematical Model and Analysis of Pneumonia on Children under five years with Malnutrition
Authors: Ndendya Jufren , Liana Yustina 
Published: March 2024

Abstract

Pneumonia is an infection that affects one or both lungs and is caused by fungus, bacteria, or viruses while Malnutrition is defined as a dietary imbalance. Pneumonia and malnutrition are two different illnesses, however, they often coincide andcan have a substantial impact on child mortality in pneumonia-endemic regions.Considering their geographical proximity, there has been no mathematical analysisof their co-dynamics. To address this gap, we develop a deterministic pneumonia mathematical model that divides children into two groups: well-nourished andundernourished, to investigate the potential effect of malnutrition on pneumonia dynamics. The basic reproduction number of the proposed model is computed usingthe Next-Generation Matrix and both local and global stability of the disease-freeequilibrium is examined. Using the model parameters, the sensitivity analysis isperformed by using the Normalized forward sensitivity index to establish their effects on the basic reproduction number. Furthermore, Numerical simulations areprovided based on the model parameter values chosen. The results show that individuals who are malnourished have a higher chance of acquiring and dying frompneumonia than well-nourished individuals.
Experimental evidence of the molecular and macroscopic origins of circular dichroism in chiral metal-halide networks
Authors: Abhervé Alexandre 
Published: March 2024

Abstract

Clockwise or counter-clockwise spin coating? In the current hot research topic of chiral metal-halide semiconductors, several investigations have been undertaken in order to reveal their natural optical activity and have reported dissymmetry factors (gabs) for thin films of many hybrid compounds, usually without considering the macroscopic anisotropies inherent to solid-state samples. Yet, CD in the solid state can be strongly modulated by the co-existence of linear dichroism (LD) and linear birefringence (LB). Theoretical studies recently revealed the importance of such macroscopic interferences in the CD response of solid-state samples, often referred as symmetric (sLDLB) and antisymmetric (aLDLB) effects. Based on the newly synthesized one-dimensional lead-halide networks of formula (S/R-HP1A)PbBr3 and (S/R-HP1A)PbI3, an experimental method to accurately discriminate between CD, sLDLB and aLDLB in chiral metal-halide networks is here presented. The main experimental conditions influencing sLDLB and aLDLB amplitude are also highlighted, such as the concentration of the precursor solution and the spin-coating rotation direction, finally providing a complete experimental guide for the forthcoming chiroptical investigations of such important family of chiral hybrid materials.
A Decade-Long Review: Insights into Diagnosis and Disease Trajectory of Uveitis from a Single-Center Study
Authors: Gupta Vishali , Sharma Gunjan , Arora Atul , Rojas-Carabali William , Lee Bernett , Gupta Amod , Bansal Reema , Dogra Mohit , Katoch Deeksha , Sharma Aman , Jindal Ankur , Suri Deepti , Singh Surjit , Agrawal Rupesh 
Published: March 2024

Abstract
Purpose
To analyze the evolution of uveitis diagnosis over a 10-year period, emphasizing the change in etiological diagnosis, and the factors associated with recurrences.
Design:
Retrospective chart review
Methods
A total of 15000 patients with uveitis presented to our tertiary care institute in North India between 1992 and 2023. Of these,123 patients completed 10-year follow-up and were included in the study. The data of patients was collected on an offline purpose-built uveitis registry portal:Ocular Autoimmune Systemic Inflammatory and Infectious Study(OASIS).
Results
The study included 123 patients (48.78% males; mean age:29.11 ± 15.22 years).The most common anatomical and etiological diagnosis at presentation were anterior (49/123,34.96%) and idiopathic(59/123,47.97%) uveitis respectively.At the end of 10 years, anterior uveitis remained the most common anatomical diagnosis(43/123,39.83%) while the most common etiological diagnosis was immune-mediated uveitis(50/123,40.65%). An etiological diagnosis could be established in 50.85%(30/59) of patients initially labelled as idiopathic.Tuberculous uveitis(39/44,88.63%) and Juvenile Idiopathic Arthritis associated uveitis (16/49,32.65%) were the commonest infectious and immune-mediated etiologies at the 10-year follow-up. Ninety-six(80.67%) patients experienced multiple episodes of ocular inflammation with a mean recurrences rate of 0.386 ± 0.24 recurrences/year. Anterior uveitis(p = 0.01), the change in etiological diagnosis after the first year(p = 0.03), positive HLA-B27 at baseline(p = 0.04), and the diagnosis of a systemic disease prior to onset of uveitis were associated with higher recurrences rates(p = 0.03).
Conclusion
Over 10-year of follow up, half of the uveitis diagnosis evolved from idiopathic to specific infectious or immune-mediated etiologies.Our results indicate that patients with a high recurrence rate may benefit from re-evaluation to find the definitive cause of uveitis.
Prenatal Exposure to Metal Mixture and Birth Weight; a Bayesian Kernel Machine Regression Analysis of Two Cohort Studies in Japan and Iran
Authors: Vigeh Mohsen , Yokoyama Kazuhito , Nishioka Emiko , Shamsipour Mansour , Matsukawa Takehisa , Yunesian Masud 
Published: March 2024

Abstract

Purpose
Potentially toxic metals can directly induce various adverse effects on reproductive organs or interrupt essential metals' physiological activities. Despite intensive efforts to reduce these metals in the environment, chronic and low-level exposure remains a public health problem. The present study aimed to investigate prenatal metal exposure, including arsenic (As), copper (Cu), lead (Pb), manganese (Mn), rubidium (Rb), selenium (Se), and zinc (Zn), effects on birth weight.
Methods
We collected 579 blood samples before the 16th week of gestation from apparently healthy women with singleton pregnancy in Iran and Japan. Blood metal concentrations were measured using inductively coupled plasma-mass spectrometry.
Results
Prenatal blood levels of As, Mn, Pb, and Zn were significantly higher, while Cu, Rb, and Se were significantly (p < 0.01) lower in Iranian participants than in Japanese. Adjusted linear regression analyses and Bayesian Kernel Machine Regression (BKMR) overall exposure-response functions showed inverse relationships between metals and birth weight.
Conclusion
The study findings, using data from geographically diverse countries, suggest prenatal blood metal exposure as a potential risk factor for lower birth weight. Therefore, women of reproductive age should minimize encountering to potentially toxic metals as much as possible.
Low-coordinate Cu1–N2 sites in single-atom catalyst for highly efficient propylene epoxidation with molecular oxygen
Authors: Fu Gang , Qiu Yueming , Zhang Yichen , Xiao Siqiang , Tian Jian , Zhang Ronghui , Sun Luying , Tan Kok Bing , Duh Yih-Shing , Li Qingbiao , Huang Jiale 
Published: March 2024

Abstract
Due to its sustainability, direct epoxidation of propylene into propylene oxide (PO) with molecular oxygen alone is believed to be an ideal route. Despite constant research efforts, numerous catalysts struggle with the trade-off between activity and selectivity, which typically results in poor PO yield. In this contribution, we presented an atomically distributed Cu catalyst that had precisely controlled Cu–N coordination numbers of 1:2, termed as Cu1–N2 SAC. In contrast to traditional Cu-based oxide catalysts, this catalyst features exclusive Cu–N coordination, replacing all Cu–O interactions. The synthesized Cu1–N2 SAC catalyst acquired an unprecedented PO formation rate of 5.9 mmolPO gcat–1 h–1 at 275 °C, outperforming any other catalysts reported so far. Sophisticated characterizations and density functional theory calculations revealed that the enhanced catalytic performance was attributed to exclusively forming the electrophilic oxygen species without nucleophilic oxygen species. As a result, these electrophilic oxygen species preferentially target the C=C bond instead of α C–H bond in propylene. These insights pave the way for a new avenue in the optimization of metal oxide catalysts through the precise manipulation of metal-nitrogen (M–N) coordination environments.
Investigating of the Link between Antibiotic Resistance in Patients and the Environment: A Contribution to the One Health Approach
Authors: Sarailoo Mohammad , Wallner Markus , Nogueira Regina 
Published: March 2024

Abstract

Purpose
Antibiotic resistance is a growing global concern with far-reaching implications for public health. This study investigates the link between human and environmental health monitoring data in Lower Saxony, adopting the One Health approach.
Methods
Health and environmental monitoring data are analyzed to examine the prevalence of antibiotic-resistant bacteria (ARB). To achieve this goal, existing reports publicly available in internet were reviewed and spatial and statistical tools such as ArcGIS Pro and R programming language were utilized. Health monitoring data is collected annually as part of the sentinel system ARMIN (Antimicrobial Resistance Monitoring), launched in 2006 by the Public Health Agency of Lower Saxony (Germany). Environmental monitoring data were extracted from one study conducted in 2018.
Results
Key findings suggest that the role of wastewater treatment plants (WWTPs) as sources of ARB in the environment, highlighting their limited efficiency in removing ARB. Spatial analysis reveals regional variations in ARB rates, with vancomycin-resistant enterococci (VRE) more prevalent in the East and multi-drug resistant Gram-negative bacteria (3MRGN) evenly distributed across the Western and Eastern regions in Lower Saxony.
Conclusion
Overall, this study underscores the need for comprehensive One Health surveillance programs encompassing human health and the environment to address the complex challenge of antibiotic resistance effectively.
Experience, skill and attentional capacity predict situation awareness of operators performing coronary angiography
Authors: Gallagher Anthony G , Bond Raymond R. , Currie Jonathan , Gallagher Conor J , Bunting Brendan P , Kearney Peter 
Published: March 2024

Abstract

Introduction: We evaluated the intra-operative situational awareness (as measured with detection accuracy and latency) capacity of interventional cardiologists during the performance of physics-based virtual reality simulation of a coronary angiography procedure.
Methods: Using a between groups repeated measures design we assessed experienced and mid-level interventional cardiologists (ICs) using eye tracking glasses and physics-based virtual reality simulation. We assessed their intra-operative procedure performance errors, situation awareness, and attentional capacity as they performed a coronary angiogram. The main outcomes were intra-operative performance errors, situation awareness as measure of the operators capacity and latency to detect and correctly respond to salient visual stimuli.
Results: We showed that experienced cardiologists had considerably better situation awareness. They demonstrated faster stimulus identification and report latencies (4.5 times quicker, p < 0.001). Furthermore, trainees detection latency scores strongly predicted total technical error scores (r = 0.93).
Conclusions: This study showed that experienced ICs had a greater capacity to detect, recognise, and make judgements about deviations from optimal performance intra-operatively. The results from this study almost certainly apply to all image guided medical interventional procedures and have important patient safety implications.
Quantification Of Macroplastics Under Differing Weather Conditions Near A Japanese Farmland River
Authors: Chowdhury Zahura , Yokota Kuriko , Ngoc Nguyen Minh , Inoue Takanobu 
Published: March 2024

Abstract
Plastics can long persist in nature to become an environmental issue if not taken care of properly. To understand factors affecting plastic pollution in Japan’s farmland Hamada River, this study examined quantification of macroplastics (those larger than 5 cm) during differing weather conditions. The average number of collected samples in unit area in unit amount of time during rainy days (after-rain period; 1.39 samples/hour.m2) almost doubled that of sunny days (0.87 samples/hour.m2). Sample density (g/m2) further revealed that rainfall increased the amount of plastic waste: the average plastic waste density in the Hamada River on sunny days was 2.04 g/m2, but rainy days’ samplings were 5.33 g/m2 downstream and 11.14 g/m2 upstream. Approximately 39% of samples during sunny days had an aspect ratio range of 2–5, whereas 38–46% of samples during after-rain periods had an aspect ratio range of 1–2. By more than half (53.6%), sunny days’ samplings were white; 25% were transparent, and the rest were black (7.1%), gray (3.6%), brown (3.6%), or green (7.1%). After-rain samplings showed a wider range of color variations including purple. An average of 92 pieces of macroplastic were found at each sampling, and polyethylene accounted for the majority, with an average of 70%. The majority of polyethylene samples were mulch films originating from the nearby tobacco farms.
Biodiversity conservation by Korean corporations towards nature-positive goals
Authors: Cho Yoora , Lee Jeongki , Senadheera Sachini S. , Chang Scott. X. , Rinklebe Jörg , Rhee Jay Hyuk , Ok Yong Sik 
Published: March 2024

Abstract
Overbalance of ecosystems triggers global biodiversity loss and threatens the sustainability of society by emerging financial risks from the disruption of ecosystem services. Several initiatives and international organizations have developed guidelines on biodiversity conservation to support the increasing demand for the disclosure of nature-positive business practices. However, corporations’ biodiversity-related performances have yet to undergo a comprehensive assessment, either quantitatively or qualitatively. Here we analyze the biodiversity conservation practices, or the evolution of Environmental, Social, and Governance (ESG) management, of the top 200 corporations by market capitalization in South Korea based on their sustainability reports published 2017–2021. We show that the number of corporations issuing sustainability reports doubled in five years, and over 70% issued sustainability reports in 2021. Based on the directionality of the COP15 agreement and the consistency with the targeted ecosystems, we identified that 22% of corporations report engagement with biodiversity conservation without substantive outcomes. The methodology developed can guide major corporations for biodiversity-related disclosures, including those required by the TNFD.
MHD Casson Nanofluid Flow over Convectively Heated Non-Linear via a Porous Medium: Fractional Order Analysis Based on an Extending Surface with Suction/Injection
Authors: Abdelhafez M. A. , Abd-Alla A. M. , Abo-Dahab S. M. , Alharbi F. M. , Bayones F. S. 
Published: March 2024

Abstract

An attempt is made to explain the thermophysical properties of the viscoelastic fluid flow generated by a stretched, nonlinearized surface. Here, the Casson fluid model characterizes viscoelasticity, which is then rheologically stated in the fractional momentum equation. The characteristics of Casson fluid flow are carefully examined in a transversally magnetized field with the option of suction or injection to the surface. Porousness is another attribute of flow medium. To illustrate the change in heat transmission inside the flow domain, convective heating is applied to the surface. To find out how well thermophoretic forces and Brownian motion affect particle diffusion, nanosized particles are suspended in the Cassin fluid. Mass transport measurements are also taken into account for generative chemical reactions. Flow-narrating fractional differential equations for a problem are first obtained in fractional differential equations and then, through the use of similarity, transformed into an fractional ordinary differential coupled system. Through graphical structures, variations in flow-associated distributions against relevant parameters are revealed. Additionally computed are wall drag, heat, and mass fluxes. By comparing the computed results to previously released data in a limited sense, the computing results' credibility is verified.
Genomic characterization of a novel multidrug-resistant plasmid harboring bla NDM5 in Escherichia coli sequence type 167 isolate from Zhongshan, China
Authors: Han Dengke , Ma Suzhen , He Chenhong , Yang Yuxing , Li Peng , Lu Lanfen 
Published: March 2024

Abstract
Background
The dissemination of carbapenem-resistant Enterobacteriaceae represents an emerging challenge in infection control because carbapenems are the last-resort antibiotics for treating multidrug-resistant (MDR) bacterial infections. In recent years, New Delhi metallo-β-lactamase (NDM) has become a widespread carbapenem-resistance gene that needs active surveillance.
Results
In this study, the MDR Escherichia coli (E. coli) strain GZ04-0083 carrying the blaNDM−5 plasmid was identified from the stools of a patient with diarrhea using pulsed-field gel electrophoresis (S1-PFGE) and southern blot. A conjugation experiment was conducted to assess the transferability of the resistance plasmid. Second-generation and nanopore sequencing were performed to assemble the genomics and plasmid sequence. Multi-locus sequence typing (MLST) results showed that GZ04-0083 belonged to the ST167 isolate, and a novel 146,950-bp IncF plasmid harboring the blaNDM−5 gene was identified and named pNDM-5-0083. An additional β-lactamase gene (blaTEM−1B) and five other resistance genes (sul2, dfrA12, tetA, aadA2, and rmtB) were also detected in pNDM-5-0083. The plasmid’s key elements might play significant roles in plasmid stability and resistance genes transmission, including integrator and transposon elements (Intl1, Tn21, and Tn3), a replication protein (RepA), stabilization proteins (ParA and ParB), insertion sequences (Is26, Is30, Is91, and Ins gene cluster), iron transporters (Iro, Luc, and Sit) and conjugative splice transfer systems of plasmids (Tra and Trb gene cluster). The basic local alignment search tool (BLAST) revealed that pNDM-5-0083 shared the conserved sequence RepA-blaTEM−1B-blaNDM−5-bleMBL-Is91-SuI2-addA2-dfrA12 with three other plasmids.
Conclusion
In conclusion, the results imply that the newly discovered pNDM-5-0083 plasmid could be a co-vector mediating the spread of blaNDM−5, leading to widespread β-lactam antibiotic resistance.
Screening active ingredients of traditional Chinese medicine by molecular docking technology and evaluating their reduce skin photoaging activities
Authors: Zheng Shiqian , Deng Rongrong , Huang Gengjiu , Ou Zhiwen , Shen Zhibin 
Published: March 2024

Abstract
ABSTRACTST
Objective: Screening active ingredients of traditional Chinese medicine by molecular docking technology and evaluating their anti-skin photoaging activities. Methods: According to the verification results of molecular docking, the five active ingredients are combined in equal proportion to form a compound drug. In HaCaT photoaging model, the effects of the compound drug on antioxidant, inflammatory factors of NF-κB pathway and cytokines of MAPK pathway were studied by SOD and MDA kits, DCFH-DA fluorescent probe and ELISA assays, respectively. In skin photoaging model, the effects of the compound drug on antioxidant, SASP factors of NF-κB and MAPK pathway were studied by SOD kit, MDA kit, CAT kit and ELISA assays, respectively. Results: The results showed that the compound drug increased SOD activity, decreased MDA content and intracellular ROS, inhibited IL-6 of NF-κB pathway, and inhibited MMP-1 and collagen I of MAPK pathway. The results of HE, Masson and Victoria blue skin staining showed that the compound drug inhibited abnormal thickening of the epidermis, abnormal breaking and accumulation of collagen fibers and elastic fibers, and maintained their orderly arrangement. Meanwhile, the results showed that the compound drug increased SOD and CAT activity, inhibited MDA content, inhibited SASP factors IL-6 and TNF-α of NF-κB pathway, and inhibited SASP factors MMP-1 and collagen I of MAPK pathway. Conclusion: The above results indicate that the active ingredients of the compound drug screened by molecular docking have the potential to reduce skin photoaging.