bluuebunny/crossref_metadata_2025_split huggingface dataset:
Cascade Reaction in Organic Hole Transport Layer Enables Efficient Perovskite Solar Cells
Authors: Lan Zhineng , Huang Hao , Du Shuxian , Lu Yi , Sun Changxu , Yang Yingying , Zhang Qiang , Suo Yi , Qu Shujie , Wang Min , Wang Xinxin , Yan Luyao , Cui Peng , Zhao Zhiguo , Li Meicheng 
Published: March 2024

AbstractThe doped organic hole transport layer (HTL) is crucial for achieving high‐efficiency perovskite solar cells (PSCs). However, the traditional doping strategy undergoes a time‐consuming and environment‐dependent oxidation process, which hinders the technology upgrades and commercialization of PSCs. Here, we reported a new strategy by introducing a cascade reaction in traditional doped Spiro‐OMeTAD, which can simultaneously achieve rapid oxidation and overcome the erosion of perovskite by 4‐tert‐butylpyridine (tBP) in organic HTL. The ideal dopant iodobenzene diacetate was utilized as the initiator that can react with Spiro to generate Spiro⋅+ radicals quickly and efficiently without the participation of ambient air, with the byproduct of iodobenzene (DB). Then, the DB can coordinate with tBP through a halogen bond to form a tBP‐DB complex, minimizing the sustained erosion from tBP to perovskite. Based on the above cascade reaction, the resulting Spiro‐based PSCs have a champion PCE of 25.76 % (certificated of 25.38 %). This new oxidation process of HTL is less environment‐dependent and produces PSCs with higher reproducibility. Moreover, the PTAA‐based PSCs obtain a PCE of 23.76 %, demonstrating the excellent applicability of this doping strategy on organic HTL.
Validating ΔΔG Selectivity Descriptor for Electrosynthesis of H2O2 from Oxygen Reduction Reaction
Authors: Mok Dong Hyeon , Back Seoin , Siahrostami Samira 
Published: March 2024

AbstractUnderstanding selectivity trends is a crucial hurdle in the developing innovative catalysts for generating hydrogen peroxide through the two‐electron oxygen reduction reaction (2e‐ORR). The identification of selectivity patterns has been made more accessible through the introduction of a newly developed selectivity descriptor derived from thermodynamics, denoted as ΔΔG introduced in Chem Catal. 2023, 3(3), 100568. To validate the suitability of this parameter as a descriptor for 2e‐ORR selectivity, we utilize an extensive library of 155 binary alloys. We validate that ΔΔG reliably depicts the selectivity trends in binary alloys reported for their high activity in the 2e‐ORR. This analysis also enables the identification of nine selective 2e‐ORR catalysts underscoring the efficacy of ΔΔG as 2e‐ORR selectivity descriptor. This work highlights the significance of concurrently considering both selectivity and activity trends. This holistic approach is crucial for obtaining a comprehensive understanding in the identification of high‐performance catalyst materials for optimal efficiency in various applications.
A micro‐nanohierarchical composite fabric for efficient water transport and outstanding flame retardancy
Authors: Wu Yuzhe , Su Qing , Gong Ao , Zhu Chuanren , Long Shengru , Yang Jie , Wang Xiaojun , Wei Zhimei 
Published: March 2024

AbstractTextiles with outstanding moisture transport characteristics and excellent flammability is of vital importance for human beings. In this work, the poly(arylene sulfide sulfone)–polydopamine/polyphenylene sulfide–polydopamine/poly(arylene sulfide sulfone) (PASS‐PDA/PPS‐PDA/PASS) composite fibric with multigradient porous structures from macro to submicron levels prepared via micrometer and nanometer fibers for water transport and evaporation has been fabricated. The introduction of PDA can effectively improve the hydrophilicity of the composite membrane. Meanwhile, superhydrophobic PASS layer with beaded structure was obtained by electrospray as the inner layer. It is found that PASS‐PDA‐72 fabric exhibited outstanding water diffusion property (spreading diameter = 10.47 cm) and ultrafast the water evaporation (0.20 g h−1). Meanwhile, the beaded‐structure PASS fabrics with high hydrophobicity (water contact angle is 130°C) was selected to absorb water from the surface of human skin and transport it to the other side to evaporate quickly, giving the surface of human skin a comfortable and dry environment. What is more, the PASS‐PDA/PPS‐PDA/PASS composite membrane exhibited excellent thermal stability (Tdmax = 544°C) and flame retardancy, which will have potential for the application in the field of fire protection.
A low pollution surface pretreatment of PC‐ABS under acidic conditions
Authors: Zhao Wei , Zhao Wenxia , Li Xinwei , Liu Xin , Hui Kaihong , Song Yifan , Chen Huaijun , Cui Yubo , Zhu Qian , Liu Jing , Qiao Liang , Yan Yani 
Published: March 2024

AbstractIn the present study, the low pollution acidic potassium permanganate system has been used in the study of its micro‐etching effect on polycarbonate‐acrylonitrile butadiene styrene (PC‐ABS). Prior to micro‐etching using a N methyl pyrrolidone (NMP)‐glycol butyl ether solution was used as the swelling system of PC‐ABS. Reasonable swelling conditions were determined, a 2‐min expansion period at a temperature of 35°C with an NMP concentration of 80%. After the swelling processes, the effects of the volume ratio of :, micro‐etching temperature, and micro‐etching duration on the PC‐ABS surface morphology, surface roughness, surface hydrophilicity, and peel strength, have been investigated. It was finally determined that the best micro‐etching effect could be obtained by reacting at : = 1:2 and a temperature of 60°C for 25 min. The surface of the PC‐ABS copolymers was characterized by x‐ray photoelectron spectroscopy, atomic force microscopy, and Fourier‐transform infrared spectroscopy. The results showed that the micro‐etching process changed the morphology of the PC‐ABS surface and generated cavities. In addition, the surface roughness increased from the initial Ra = 9.69 to Ra = 197 nm. Also, the water contact angle on the PC‐ABS surface decreased from 92.2° to 28.6°, and the peel strength increased to 0.98 kN/m.
Unveiling the impact of housing debt on entrepreneurship: Evidence from China
Authors: Yu Xiaofen , Hu Dingpei , Hu Mingzhi 
Published: March 2024

AbstractDespite extensive research on the impact of various factors on entrepreneurship, the role of housing debt remains underexplored, particularly in emerging economies. Using data from the China Household Finance Survey (CHFS), this study identifies a significant negative effect of housing debt on entrepreneurship after controlling for a comprehensive set of individual and household characteristics, as well as regional and year fixed effects. To delve deeper into the underlying mechanisms, we present direct evidence that housing debt amplifies risk aversion while imposing capital and credit constraints. Furthermore, we offer indirect evidence suggesting that housing debt exerts a stronger negative impact on employer entrepreneurship than on self‐employment entrepreneurship, and a more pronounced negative effect on active entrepreneurship compared to passive entrepreneurship. Overall, this study addresses gaps in research on the impact of housing debt on entrepreneurship and provides insights into the underlying mechanisms by revealing how housing debt amplifies risk aversion, imposes capital and credit constraints, and disproportionately affects employer entrepreneurship over self‐employment entrepreneurship, as well as active entrepreneurship over passive entrepreneurship.
Synovial 5‐Lipoxygenase–Derived Oxylipins Define a Lympho‐Myeloid–Enriched Synovium
Authors: Murillo‐Saich Jessica D. , Coras Roxana , Ramirez Julio , Quesada‐Masachs Estefania , Sala‐Climent Marta , Eschelbach Katharina , Mahony Christopher B. , Celis Raquel , Armando Aaron , Quehenberger Oswald , Croft Adam P. , Kavanaugh Arthur , Chang Eric , Cañete Juan D. , Singh Abha , Guma Monica 
Published: March 2024

ObjectiveOxylipins are bioactive lipids derived from polyunsaturated fatty acids (PUFAs) that modulate inflammation and may remain overexpressed in refractory synovitis. In plasma, they could also be biomarkers of synovial pathology. The aim of this study is to determine if synovial oxylipins in inflamed joints correlate with plasma oxylipins and with synovial histologic patterns.MethodsPatients with established rheumatoid or psoriatic arthritis with active disease despite treatment were recruited, and paired synovial tissue (ST) and plasma were collected. Oxylipins were determined by liquid chromatography with tandem mass spectrometry and were classified into groups according to their PUFA precursor and enzyme. The expression of CD20, CD68, CD3, and CD138 was obtained to describe synovial histology. Cell‐specific expression of oxylipin‐related genes was identified by examining available synovial single‐cell RNA sequencing data.ResultsWe included a total of 32 ST and 26 paired‐plasma samples. A total of 71 oxylipins were identified in ST, but only 24 were identified in plasma. Only levels of 9,10‐dihydroxyoctadecenoic acid and tetranor‐Prostaglandin FM had a significant positive correlation between plasma and ST. Several oxylipins and oxylipin‐related genes were differentially expressed among synovial phenotypes. Specifically, several 5‐lipoxygenase (LOX)–derived oxylipins were statistically elevated in the lympho‐myeloid phenotype and associated with B cell expression in rheumatoid arthritis samples.ConclusionThe lack of correlation between ST and plasma oxylipins suggests that ST lipid profiling better characterizes active pathways in treated joints. Synovial 5‐LOX–derived oxylipins were highly expressed in lympho‐myeloid–enriched synovium. Combination therapy with 5‐LOX inhibitors to improve refractory inflammation may be needed in patients with this histologic group.image
An analysis of the relationship of “the Mozart effect” with BDNF levels in anatomy education
Authors: Petekkaya Emine , Ünalmış Aykar Demet , Kaptan Zülal 
Published: March 2024

AbstractIn 1993, an increase was observed in the spatial IQ scores of the volunteers who listened to Mozart's sonata K448 for 10 min, and this phenomenon entered the literature as the “Mozart effect.” Other studies have shown that this effect is particularly evident in spatial skill tests. A large body of research has provided evidence that spatial ability is associated with success in learning anatomy. In this study, Kastamonu University Faculty of Medicine students were divided into two groups during 16‐h practical training spanning 30 days. While one of the groups listened to Mozart's K448 sonata as the background music in all lessons, the control group attended the lessons in their standard form. At the end of each lesson, all students solved a modified mental rotation test including questions involving anatomical structures. Before starting the study, after the first laboratory class, on the 15th and 30th day of the study, blood samples were taken from the participants, and plasma brain‐derived neurotrophic factor (BDNF) levels were determined. The effect of time on mental rotation score and plasma BDNF level was significant (p < 0.001 for both). The effect of group was also significant (p < 0.001 for both). Pairwise comparisons showed significance in the fifth, sixth, seventh, and eighth mental rotation test (p < 0.001, p = 0.041, p < 0.001, p < 0.001, respectively) and in the third (Day 15) and fourth (Day 30) BDNF measurement (p < 0.001 for both). Our findings may indicate that specific background music may be useful for anatomy teaching.
Quality of life outcomes after transobturator tape full removal surgeries: A monocentric experience
Authors: Perrouin‐Verbe Marie‐Aimee , Ochoa D‐Carolina , Skews Rachel , Acharya Mez , Prouza Antonin , Hashim Hashim 
Published: March 2024

AbstractObjectiveThe objective of this study is to describe a standardised technique of full TOT removal with groin dissection and to report clinical improvement, satisfaction, safety and long‐term functional, quality of life (QoL) and sexual QoL outcomes.Materials and methodsA retrospective review enrolling all women who had full TOT removal, in a tertiary referral centre from May 2017 to November 2020. Functional outcomes, satisfaction and QoL were assessed using a bespoke composite questionnaire (UDI‐6, EQ‐5D‐5L and ICIQ‐S) with additional questions on sexual QoL. Secondary outcomes were post‐operative recurrent stress urinary incontinence (SUI) and complication rate according to the Clavien‐Dindo classification.ResultsFull TOT removal using a vaginal approach and bilateral groin/para‐labial incisions was performed in 67 patients. Chronic pelvic pain was the main indication for mesh removal (51% of cases, n = 34). QoL questionnaires were answered by 43 patients. The satisfaction rate was high 86% (n = 37), and 81% (n = 35) of the patients considered the surgery successful. Seventy per cent (n = 30) of patients returned to having a sexual life after surgery. Recurrent SUI was reported in 32% (n = 14) of cases. The complication rate was 10% (7/67), all of them Clavien–Dindo ≤2.ConclusionDespite a high rate of postoperative bothersome SUI, full TOT removal with bilateral groin dissection improves pain and QoL. It is associated with a high overall satisfaction rate and an acceptable rate of complications.
Evaluation of in vitro corrosion behavior and biocompatibility of poly[xylitol‐(1,12‐dodecanedioate)](PXDD)‐HA coated porous iron for bone scaffolds applications
Authors: Md Yusop Abdul Hakim , Wan Ali Wan Fahmin Faiz , Jamaludin Farah Hidayah , Szali Januddi Fatihhi , Sarian Murni Nazira , Saad Norazalina , Wong Tuck‐Whye , Hidayat Arif , Nur Hadi 
Published: March 2024

AbstractThe present study evaluates the corrosion behavior of poly[xylitol‐(1,12‐dodecanedioate)](PXDD)‐HA coated porous iron (PXDD140/HA‐Fe) and its cell‐material interaction aimed for temporary bone scaffold applications. The physicochemical analyses show that the addition of 20 wt.% HA into the PXDD polymers leads to a higher crystallinity and lower surface roughness. The corrosion assessments of the PXDD140/HA‐Fe evaluated by electrochemical methods and surface chemistry analysis indicate that HA decelerates Fe corrosion due to a lower hydrolysis rate following lower PXDD content and being more crystalline. The cell viability and cell death mode evaluations of the PXDD140/HA‐Fe exhibit favorable biocompatibility as compared to bare Fe and PXDD‐Fe scaffolds owing to HA's bioactive properties. Thus, the PXDD140/HA‐Fe scaffolds possess the potential to be used as a biodegradable bone implant.
Systematic derivatives of 1‐(dicyanomethylene)indan and their photophysical properties as potential viscosity sensors
Authors: Roh Tae‐Ho , Ko Min‐Sung , Desale Pradeep P. , Cho Dong‐Gyu 
Published: March 2024

AbstractThis study focuses on derivatizing 1‐(dicyanomethylene)indan as a viscosity sensor. The indan was extended with various functionalized naphthaldehydes under a push–pull design strategy. Among synthesized derivatives, salt‐capped derivatives exhibited an excellent linearity between fluorescent intensity and viscosity (R2 = 0.99), and further investigation underscores the reversible nature of fluorescence intensity changes at two temperatures as an important trait of viscosity sensors.
Sustainability‐oriented innovation in manufacturing firms: Implementation and evaluation framework
Authors: Harsanto Budi , Kumar Niraj , Michaelides Roula 
Published: March 2024

AbstractIn this paper, complementary perspectives from innovation management capabilities (IMC), the natural resource‐based view (NRBV) and the social resource‐based view (SRBV) are revisited in order to lay the theoretical foundation for developing evaluation framework for sustainability‐oriented innovation (SOI). Six dimensions of SOI are identified, as innovation focus, sustainability focus, integration intra‐organisation, integration inter‐organisation, ambidexterity, and emphasis on physical life cycle — which then lead to developing the key parameters for the evaluation framework. The proposed framework is validated through analysis of 25 cases from the manufacturing sector in Indonesia. Data were primarily collected through semi‐structured interviews and analysed using a polar diagram. This approach offered a comprehensive understanding of the qualitative data by assessing all six SOI dimensions simultaneously, presenting an effective visualisation of the firms' approach to SOI. The findings suggest that the majority of firms tend to adopt an operational optimisation approach when developing their SOI, while only a few opt for organisational transformational, and none choose the system building approach. This research paper makes a significant contribution to literature by introducing transition phases among SOI approaches, which were previously not explored in literature. The framework developed in this study would provide valuable support to practitioners in implementation and enhancement of their SOI practices.
Molecular Docking, Synthesis, and Characterization of Furanyl‐Pyrazolyl Acetamide and 2,4‐Thiazolidinyl‐Furan‐3‐Carboxamide Derivatives as Neuroinflammatory Protective Agents
Authors: Mudimela Sowjanya , Giridharan Vijayasree V. , Janardhan Saravanan 
Published: March 2024

AbstractMicroglia are key immune cells in the brain that maintain homeostasis and defend against immune threats. Targeting the dysfunctional microglia is one of the most promising approaches to inhibit neuroinflammation. In the current study, a diverse series of molecular hybrids were designed and screened through molecular docking against two neuroinflammatory targets, namely HMGB1 (2LY4) and HMGB1 Box A (4QR9) proteins. Based on the outcomes of docking scores fifteen compounds; ten furanyl‐pyrazolyl acetamides 11(a–j), and five 2,4‐thiazolidinyl‐furan‐3‐carboxamide 15(a–e) derivatives were selected for further synthesis, followed by biological evaluation. The selected compounds, 11(a–j) and 15(a–e) were successfully synthesized with moderate to good yields, and structures were confirmed by IR, NMR, and mass spectra. The in‐vitro cytotoxicity was evaluated on microglial cells namely BV‐2, N‐9, HMO6, leukemic HAP1, and human fibroblast cells. Further western‐blot analysis revealed that 11h, 11f, 11c, 11j, 15d, 15c, 15e, and 15b compounds significantly suppressed anti‐inflammatory markers such as TNF‐α, IL‐1, IL‐6, and Bcl‐2. All derivatives were moderate in potency compared to reference doxorubicin and could potentially act as novel anti‐neuroinflammatory agents. This study can act as a beacon for further research in the application of furan‐pyrazole and furan‐2,4‐thiazolidinediones as lead moieties for anti‐neuroinflammatory and related diseases.
Emodin Blocks mPTP Opening and Improves LPS‐Induced HMEC‐1 Cell Injury by Upregulation of ATP5A1
Authors: Di Tietao , He Limin , Shi Qing , Chen Lu , Zhu Lei , Zhao Sisi , Zhang Chunling 
Published: March 2024

AbstractBackground: Emodin has been shown to exert anti‐inflammatory and cytoprotective effects. Our study aimed to identify a novel anti‐inflammatory mechanism of emodin. Methods: An LPS‐induced model of microvascular endothelial cell (HMEC‐1) injury was constructed. Cell proliferation was examined using a CCK‐8 assay. The effects of emodin on reactive oxygen species (ROS), cell migration, the mitochondrial membrane potential (MMP), and the opening of the mitochondrial permeability transition pore (mPTP) were evaluated. Actin‐Tracker Green was used to examine the relationship between cell microfilament reconstruction and ATP5A1 expression. The effects of emodin on the expression of ATP5A1, NALP3, and TNF‐α were determined. After treatment with emodin, ATP5A1 and inflammatory factors (TNF‐α, IL‐1, IL‐6, IL‐13 and IL‐18) were examined by Western blotting. Results: Emodin significantly increased HMEC‐1 cell proliferation and migration, inhibited the production of ROS, increased the mitochondrial membrane potential, and blocked the opening of the mPTP. Moreover, emodin could increase ATP5A1 expression, ameliorate cell microfilament remodeling, and decrease the expression of inflammatory factors. In addition, when ATP5A1 was overexpressed, the regulatory effect of emodin on inflammatory factors was not significant. Conclusion: Our findings suggest that emodin can protect HMEC‐1 cells against inflammatory injury. This process is modulated by the expression of ATP5A1.
Pulvinic Acid Derivative Pigments in Lanmaoa asiatica and L. macrocarpa
Authors: Wang Yixiao , Lüli Yunjiao , Li Xuan , Yang Zhu L. , Luo Hong 
Published: March 2024

AbstractLanmaoa asiatica G. Wu & Zhu L. Yang and L. macrocarpa N. K. Zeng, H. Chai & S. Jiang are two important gourmet bolete in China, and locally named “Jian Shou Qing” meaning their fruiting bodies turn blue after bruising. The genus represents a distinct lineage in Boletaceae. The pigment(s) associated with the discoloration in Lanmaoa has not been identified. The aim of this study was to determine the pigment(s) underpinning the bluing reaction of L. asiatica and L. macrocarpa when bruised. Potential compounds were isolated by HPLC and identified by LC‐HRMS and NMR. In total five to six pigments of hydroxylated pulvinic acid derivatives were detected with similar distribution patterns in both L. asiatica and L. macrocarpa, which by abundance were variegatic acid, variegatorubin, xerocomic acid (and/or isoxerocomic acid), xerocomorubin, and atromentic acid. Variegatic acid, the most abundant pigment, was isolated by HPLC, and the structure was further characterized by NMR. The amount of variegatic acid increased after regular cooking, which may suggest its enhanced health benefit as human diet. The types of pigments that cause bluing reactions often differ among families of Boletales. Our results showed that the pigments in Lanmaoa belong to the category of hydroxylated pulvinic acid derivatives, the major bluing compounds in Boletaceae.
Future Research Directions in the Partial Oxidation of Methane to Methanol Over Copper‐Containing Zeolites
Authors: Ogunleye Motunrayo , Pokhrel Jeewan , Shantz Daniel F. 
Published: March 2024

AbstractThe direct partial oxidation of methane to methanol is a potentially transformative approach to upgrading methane to higher value molecules. Copper‐exchanged zeolites show potential to achieve this aim and have been extensively reported and reviewed in the open literature. This concept paper highlights selected works that point to knowledge gaps in this space, which opens opportunities for further breakthroughs. Specifically, these literature reports highlight the need for 1) additional research exploring how reactor operating conditions (space velocity, feed composition, temperature) can be optimized to improve methanol selectivity, 2) developing a better understanding of how the zeolite topology impacts the reactivity of methane, and 3) how different methods of loading copper into the zeolite impact reactivity.