bluuebunny/crossref_metadata_2025_split huggingface dataset:
Modelling business performance from marketing practices of architecture firms in Nigeria
Authors: Maina Joy Joshua 
Published: March 2024

Purpose
This study aims to establish marketing practices which predict business performance of architecture firms within the Nigerian Construction Industry (NCI) to address the sustained poor business performance of firms, which affects allied professionals as many projects in the built environment depend on design proposals from architects.

Design/methodology/approach
Survey responses from 86 firms were used to model business performance measured as total revenue of the firms from 40 commonly deployed marketing practices in construction.

Findings
Two-thirds of the marketing practices most used by architectural firms were ineffective in predicting business performance. The model also explains up to half the variance in business performance (37.4–49.9%), supporting the view that marketing in the CI affects business performance. Researching client needs and competitors emerged as the only significant positive predictor of business performance (β = 0.827, p = 0.043). Using social media (β = −1.247, p = 0.004), regular participation in awards/competitions (β = −1.420, p = 0.013) and inclusion of political offers in bids (β = −1.050, p = 0.016) negatively predicted business performance.

Practical implications
Architecture and allied professional bodies in Nigeria need to rethink existing restrictions regarding marketing based on traditional code of ethics in light of present-day realities of digital and internet business environments. Principals and management of architecture firms require a paradigm shift in deploying the appropriate marketing practices, especially as it relates to research regarding changing client expectations and current competition within the NCI.

Originality/value
The study established marketing practices which model business performance and demonstrate their value in a framework for improving the financial sustainability of architecture firms within the NCI.
Trust in embedding co-design for innovation and change: considering the role of senior leaders and managers
Authors: Bedenik Tina , Kearney Claudine , Ní Shé Éidín 
Published: March 2024

PurposeIn this viewpoint article, the authors recognize the increased focus in health systems on co-design for innovation and change. This article explores the role of leaders and mangers in developing and enhancing a culture of trust in their organizations to enable co-design, with the potential to drive innovation and change in healthcare.Design/methodology/approachUsing social science analyses, the authors argue that current co-design literature has limited focus on interactions between senior leaders and managers, and healthcare staff and service users in supporting co-designed innovation and change. The authors draw on social and health science studies of trust to highlight how the value-based co-design process needs to be supported and enhanced. We outline what co-design innovation and change involve in a health system, conceptualize trust and reflect on its importance within the health system, and finally note the role of senior leaders and managers in supporting trust and responsiveness for co-designed innovation and change.FindingsHealthcare needs leaders and managers to embrace co-design that drives innovation now and in the future through people – leading to better healthcare for society at large. As authors we argue that it is now the time to shift our focus on the role of senior managers and leaders to embed co-design into health and social care structures, through creating and nurturing a culture of trust.Originality/valueBuilding public trust in the health system and interpersonal trust within the health system is an ongoing process that relies upon personal behavior of managers and senior leaders, organizational practices within the system, as well as political processes that underpin these practices. By implementing managerial, leadership and individual practices on all levels, senior managers and leaders provide a mechanism to increase both trust and responsiveness for co-design that supports innovation and change in the health system.
Environmental tax, renewable energy and environmental sustainability in Germany: evidence from wavelet and Fourier-based approaches
Authors: Ali Minhaj , Kirikkaleli Dervis 
Published: March 2024

PurposeIn order to achieve sustainable development objectives, safeguard the ecosystem, combat global warming and preserve biodiversity for a more sustainable and secure future, the ecological footprint (EF) must be reduced. Therefore, embracing holistic methods, emphasizing renewable energy (RN) and environmental taxes (ET) is crucial. Therefore, the present study aims to capture the effect of ET and RN on EF in Germany.Design/methodology/approachTo achieve this aim, the novel Fourier-based Autoregressive Distributive Lag (ADL) cointegration and the time and frequency-based connections among the variables are investigated in this work throughout the 1994–2021 time span using the wavelet analytic methods, including wavelet power spectrum (WPS) and wavelet coherence (WC) methods, respectively.FindingsThe study’s results express that (1) RN, ET and EF are cointegrated in the long run; (2) EF and RN have volatility; (3) RN use in Germany prevents environmental deterioration and (4) ET decreases EF.Practical implicationsThe research findings imply that Germany needs rigorous environmental restrictions and enforcement of alternate energy sources for energy use plans and sustainable production objectives.Originality/valueTo the best of our knowledge, the effect of RN and ET on EF in Germany has not been comprehensively explored by using newly developed econometrics techniques and a single dataset. Therefore, the study provides important policy implementations for the German government and is also likely to open debate on the concept.
Enhancing word of mouth in the quick service restaurants: role of perceived brand globalness and localness
Authors: Ghorbanzadeh Davood , Rahehagh Atena , Ghiyasi Maryam 
Published: March 2024

Purpose
Due to changing consumer thinking patterns and market dynamics, the quick service restaurant (QSR) industry has changed dramatically in the past few years. Considering this, this study aims to examine the influence of perceived brand globalness and perceived brand localness on consumer word of mouth through brand attitude by considering consumer ethnocentrism and perceived brand origin as moderators.

Design/methodology/approach
This study obtained 750 responses from Turkish consumers through a survey and analyzed the data using the maximum-likelihood estimation technique with structural equation modeling.

Findings
This study discovered that perceived brand globalness and perceived brand localness are critical components that drive brand attitude, influencing consumers' WOM toward global and local QSR brands. Similarly, perceived brand globalness and perceived brand localness are important brand attributes influencing consumer WOM. Importantly, this study found the significant effects of perceived brand origin on brand attitude mainly toward perceived local brands compared to global QSR brands. Although this study did not uncover the influence of consumer ethnocentrism as expected. However, these insights may assist global and local managers to rethink their strategies toward Turkish consumer settings.

Research limitations/implications
This study was conducted exclusively in Turkey. However, additional studies in other countries, such as the comparative Asian versus European consumers' perspectives, may be considered to generalize the findings.

Practical implications
This study provides recommendations to global and local managers to support them in designing and executing several brand positioning strategies in the QSR industry.

Originality/value
This novel study contributes to the accessibility diagnostic theory and signaling theory by examining consumers' perceptions of local and global brands.
Tourism academia: a Horizon 2050 paper
Authors: Schweinsberg Stephen , Fennell David A. 
Published: March 2024

Purpose
The purpose of this paper is to chart the history of tourism academia and offer observations as to its future development in the 21st century.

Design/methodology/approach
This paper uses a limited review of the literature and the personal reflections of the authors as its main approaches.

Findings
In reviewing the multi-generational history of tourism academia, it became apparent that whilst we have become a more scientifically rigorous community of scholars, a challenge for the academy going forward will be how best to cultivate a spirit of understanding among different parts of the academy when presented with viewpoints that do not appear to coalesce with one’s understanding of “truth”.

Originality/value
This paper contributes to scholarly debates over the history and future of tourism academia by challenging the academy to reflect critically on its increasing diversity and how to incorporate diverse viewpoints into the tourism knowledge canon.
International exchange on the clinical practice and research of rheumatic skin diseases: A report of the 5th International Conference of Cutaneous Lupus Erythematosus
Authors: Hasegawa Minoru , Chasset François , Chong Benjamin F. , Fiorentino David F. , Fujimoto Manabu , Nyberg Filippa , Sato Shinichi , Wenzel Joerg , Werth Victoria P. 
Published: March 2024

AbstractThe 5th International Conference of Cutaneous Lupus Erythematosus was held in Tokyo, Japan on May 9 and 10, 2023. The latest topics on the pathogenesis, diagnosis, assessment, and treatment of cutaneous lupus erythematosus, dermatomyositis, and scleroderma (systemic sclerosis, morphea) were presented by experts in each field and new developments discussed. In these rheumatic skin diseases, many clinical trials of novel therapies targeting cytokines, signaling molecules, plasmacytoid dendritic cells, B cells, and other molecules are currently underway, and standardization of outcome assessment was discussed. In addition, the selection of the therapeutic agents available for the diversity of each case is becoming more important, together with the ongoing pathophysiological analysis of the diseases. The achievements of this conference will further promote the development of clinical practice and research in rheumatic skin diseases through international exchange among researchers. We hope that by reporting a summary of the conference in this manuscript, we can share its contents with readers.
Declining potential nectar production of the herb layer in temperate forests under global change
Authors: De Schuyter Wim , De Lombaerde Emiel , Depauw Leen , De Smedt Pallieter , Stachurska‐Swakoń Alina , Orczewska Anna , Teleki Balázs , Jaroszewicz Bogdan , Closset Déborah , Máliš František , Mitchell Fraser , Schei Fride Høistad , Peterken George , Decocq Guillaume , Van Calster Hans , Šebesta Jan , Lenoir Jonathan , Brunet Jörg , Reczyńska Kamila , Świerkosz Krzysztof , Diekmann Martin , Kopecký Martin , Chudomelová Markéta , Hermy Martin , Macek Martin , Newman Miles , Wulf Monika , Vild Ondřej , Eriksson Ove , Horchler Peter , Petrik Petr , Pielech Remigiusz , Heinken Thilo , Dirnböck Thomas , Nagel Thomas A. , Durak Tomasz , Standovár Tibor , Naaf Tobias , Schmidt Wolfgang , Baeten Lander , De Frenne Pieter , Bernhardt‐Römermann Markus , Hédl Radim , Waller Don , Verheyen Kris 
Published: March 2024

Abstract

Wild pollinators are crucial for ecosystem functioning and human food production and often rely on floral resources provided by different (semi‐) natural ecosystems for survival. Yet, the role of European forests, and especially the European forest herb layer, as a potential provider of floral resources for pollinators has scarcely been quantified.

In this study, we measured the potential nectar production (PNP) of the forest herb layer using resurvey data across 3326 plots in temperate forests in Europe, with an average time interval of 41 years between both surveys in order to assess (i) the importance of the forest herb layer in providing nectar for wild pollinators, (ii) the intra‐annual variation of PNP, (iii) the overall change in PNP between survey periods and (iv) the change in intra‐annual variation of PNP between survey periods. The PNP estimates nectar availability based on the relative cover of different plant species in the forest herb layer. Although PNP overestimates actual nectar production, relative differences amongst plots provide a valid and informative way to analyse differences across time and space.

Our results show that the forest herb layer has a large potential for providing nectar for wild pollinator communities, which is greatest in spring, with an average PNP of almost 16 g sugar/m2/year. However, this potential has drastically declined (mean plot‐level decline >24%).

Change in light availability, associated with shifts in canopy structure and canopy composition, is the key driver of temporal PNP changes.

Synthesis. Our study shows that if management activities are carefully planned to sustain nectar‐producing plant species for wild pollinators, European forest herb layers and European forests as a whole can play key roles in sustaining wild pollinator populations.
Wolbachia strain wAlbB shows favourable characteristics for dengue control use in Aedes aegypti from Burkina Faso
Authors: Mancini Maria Vittoria , Murdochy Shivan M. , Bilgo Etienne , Ant Thomas H. , Gingell Daniel , Gnambani Edounou Jacques , Failloux Anna‐Bella , Diabate Abdoulaye , Sinkins Steven P. 
Published: March 2024

AbstractDengue represents an increasing public health burden worldwide. In Africa, underreporting and misdiagnosis often mask its true epidemiology, and dengue is likely to be both more widespread than reported data suggest and increasing in incidence and distribution. Wolbachia‐based dengue control is underway in Asia and the Americas but has not to date been deployed in Africa. Due to the genetic heterogeneity of African Aedes aegypti populations and the complexity of the host‐symbiont interactions, characterization of key parameters of Wolbachia‐carrying mosquitoes is paramount for determining the potential of the system as a control tool for dengue in Africa. The wAlbB Wolbachia strain was stably introduced into an African Ae. aegypti population by introgression, and showed high intracellular density in whole bodies and different mosquito tissues; high intracellular density was also maintained following larval rearing at high temperatures. No effect on the adult lifespan induced by Wolbachia presence was detected. Moreover, the ability of this strain to strongly inhibit DENV‐2 dissemination and transmission in the host was also demonstrated in the African background. Our findings suggest the potential of harnessing Wolbachia for dengue control for African populations of Ae. aegypti.
Risk factors and a nomogram for predicting cognitive frailty in Chinese patients with lung cancer receiving drug therapy: A single‐center cross‐sectional study
Authors: Li Jinping , Wang Yan , Zhai Minfeng , Qin Mengyuan , Zhao Dandi , Xiang Qian , Shao Zaoyuan , Wang Panrong , Lin Yan , Dong Yiting , Liu Yan 
Published: March 2024

AbstractBackgroundTo identify independent factors of cognitive frailty (CF) and construct a nomogram to predict cognitive frailty risk in patients with lung cancer receiving drug therapy.MethodsIn this cross‐sectional study, patients with lung cancer undergoing drug therapy from October 2022 to July 2023 were enrolled. The data collected includes general demographic characteristics, clinical data characteristics and assessment of tools for cognitive frailty and other factors. Logistic regression was harnessed to determine the influencing factors, R software was used to establish a nomogram model to predict the risk of cognitive frailty. The enhanced bootstrap method was employed for internal verification of the model. The performance of the nomogram was evaluated by using calibration curves, the area under the receiver operating characteristic curve, and decision curve analysis.ResultsA total of 372 patients were recruited, with a cognitive frailty prevalence of 56.2%. Age, education background, diabetes mellitus, insomnia, sarcopenia, and nutrition status were identified as independent factors. Then, a nomogram model was constructed and patients were classified into high‐ and low‐risk groups with a cutoff value of 0.552. The internal validation results revealed good concordance, calibration and discrimination. The decision curve analysis presented prominent clinical utility.ConclusionsThe prevalence of cognitive frailty was higher in lung cancer patients receiving drug therapy. The nomogram could identify the risk of cognitive frailty intuitively and simply in patients with lung cancer, so as to provide references for early screening and intervention for cognitive frailty at the early phases of drug treatment.
Genomic dissection of brown planthopper, Nilaparvata lugens (Hemiptera: Delphacidae) resistance in Indica rice genotypes
Authors: Meher Chanchala , Guru‐Pirasanna‐Pandi Govindharaj , Babu Soumya Bharati , Parameswaran Chidambaranathan , Samal Tribikram , Sah Rameswar Prasad , Anilkumar C. , Gadratagi Basana‐Gowda , Rath Prakash Chandra , Sabarinathan S. 
Published: March 2024

AbstractThe population growth and the regular breakout of Nilaparvata lugens pose a significant risk to rice cultivation. Four different N. lugens biotypes have been identified worldwide, with biotype 4 being the most destructive and prevalent throughout Asia, particularly in India. Therefore, a rice variety with multiple resistance genes/alleles is required for effective management of N. lugens. Hence, 191 rice genotypes collected from various parts of India were evaluated for resistance to N. lugens. Further, SSR markers representing 23 different N. lugens resistant (R) genes were assayed to identify genomic regions associated with resistance. The results of the genetic analysis showed that the average genetic diversity value of all markers was 0.165 and polymorphic information content of 0.145 for all the markers used. The population structure and cluster analysis divided the studied genotypes into three distinct groups, with resistant genotypes grouped separately. These findings were confirmed by the principal coordinate analysis, which categorized resistant genotypes, moderately resistant genotypes, and susceptible genotypes into distinct components. Additionally, 90% of the genetic variation was between individuals of populations and 10% between the populations. Marker‐trait association study through mixed linear model and generalized linear model identified six SSR markers such as RM6732 (Bph15), RM314 (Bph6), RM16999 (Bph6), RM7 (QBph3), RM401 (bph4), and RM7102 (Bph1), which were significantly associated with various phenotypic parameters, such as feeding mark, honeydew excretion, percent damage and nymphal survival. The resistant genes identified in these genotypes could help in the marker‐assisted rice variety development with durable resistance against N. lugens.
Ercc1 DNA repair deficiency results in vascular aging characterized by VSMC phenotype switching, ECM remodeling, and an increased stress response
Authors: van der Linden Janette , Stefens Sanne J. M. , Heredia‐Genestar José María , Ridwan Yanto , Brandt Renata M. C. , van Vliet Nicole , de Beer Isa , van Thiel Bibi S. , Steen Herman , Cheng Caroline , Roks Anton J. M. , Danser A. H. Jan , Essers Jeroen , van der Pluijm Ingrid 
Published: March 2024

AbstractCardiovascular diseases are the number one cause of death globally. The most important determinant of cardiovascular health is a person's age. Aging results in structural changes and functional decline of the cardiovascular system. DNA damage is an important contributor to the aging process, and mice with a DNA repair defect caused by Ercc1 deficiency display hypertension, vascular stiffening, and loss of vasomotor control. To determine the underlying cause, we compared important hallmarks of vascular aging in aortas of both Ercc1Δ/− and age‐matched wildtype mice. Additionally, we investigated vascular aging in 104 week old wildtype mice. Ercc1Δ/− aortas displayed arterial thickening, a loss of cells, and a discontinuous endothelial layer. Aortas of 24 week old Ercc1Δ/− mice showed phenotypical switching of vascular smooth muscle cells (VSMCs), characterized by a decrease in contractile markers and a decrease in synthetic markers at the RNA level. As well as an increase in osteogenic markers, microcalcification, and an increase in markers for damage induced stress response. This suggests that Ercc1Δ/− VSMCs undergo a stress‐induced contractile‐to‐osteogenic phenotype switch. Ercc1Δ/− aortas showed increased MMP activity, elastin fragmentation, and proteoglycan deposition, characteristic of vascular aging and indicative of age‐related extracellular matrix remodeling. The 104 week old WT mice showed loss of cells, VSMC dedifferentiation, and senescence. In conclusion, Ercc1Δ/− aortas rapidly display many characteristics of vascular aging, and thus the Ercc1Δ/− mouse is an excellent model to evaluate drugs that prevent vascular aging in a short time span at the functional, histological, and cellular level.
Prospective evaluation of single‐dose aminoglycosides for treatment of complicated cystitis in the emergency department
Authors: Jenrette Jordan E. , Coronato Kyle , Miller Matthew A. , Molina Kyle C. , Quinones Alexander , Jacknin Gabrielle 
Published: March 2024

AbstractBackgroundAntimicrobial resistance among Enterobacterales continues to be a growing problem, particularly in those with urinary infections. Previous studies have demonstrated safety and efficacy with the use of single‐dose aminoglycosides in uncomplicated cystitis. However, data in complicated infections are limited. Single‐dose aminoglycosides may provide a convenient alternative for those with or at risk for resistant pathogens causing complicated urinary infections, especially when oral options are unavailable due to resistance, allergy, intolerance, or interactions with other medications. This study evaluated the safety and effectiveness of single‐dose aminoglycosides in treatment of complicated cystitis in the emergency department (ED).MethodsThis was a multicenter, prospective study performed between July 2022 and March 2023 of patients who met criteria for complicated cystitis and were otherwise stable for discharge at an academic ED. Primary outcomes were clinical or microbiologic failure within 14 days of treatment. Safety was assessed by review of adverse events. Descriptive statistics were used.ResultsThirteen patients were included. Complicating factors were male sex (n = 4), kidney stone (n = 2), urinary catheter (n = 6), recent urologic procedure (n = 1), urinary hardware (n = 1), antibiotic allergy precluding use of alternate oral options (n = 4), immunocompromised status (n = 2), and <1‐year history of multidrug‐resistant organisms on urine culture (n = 8). Eleven patients (85%) had positive urine cultures in the preceding 12 months with no oral antimicrobial option. Eight patients (62%) received amikacin (median dose 15 mg/kg), four patients (31%) received gentamicin (median dose 5 mg/kg), and one patient (8%) received tobramycin (5 mg/kg) for treatment. Ten patients (77%) reported resolved urinary symptoms after treatment and 11 patients (85%) reported no new urinary symptoms since discharge. No patient required hospital admission for treatment failure, and no adverse events were noted.ConclusionsSingle‐dose aminoglycosides appear to be a reasonably effective and safe treatment for complicated cystitis, which avoided hospital admission in this cohort.