bluuebunny/crossref_metadata_2025_split huggingface dataset:
Polyviologen Modified Glassy Carbon Electrode Employed for Anodic Stripping Voltammetric Determination of Mercury(II)
Authors: Cheng Kuan‐Chiao , Chen Po‐Yu 
Published: October 2007

AbstractIn this study, a polyviologen modified glassy carbon electrode (PVGCE) was used to detect Hg(II) in aqueous solutions containing significant amounts of chloride anions in order to demonstrate the electroanalytical application of the electropolymerized polyviologen. The polyviologen thin film was formed on the electrode surface by applying a constant potential of −1.0 V in the pH 4.2 Britton–Robinson (BR) buffer solution that contains 0.1 wt% of viologen oligomers. The PVGCE was found capability to improve the detection limit of Hg(II) in the solutions with high concentration of chloride because Hg(II) forms negative complex ions HgCl$\rm{ {_{4}^{2-}}}$ that can be accumulated to PVGCE by the anion‐exchange characteristic of polyviologen. With 5 minutes accumulation at −0.2 V, the adsorbed HgCl$\rm{ {_{4}^{2-}}}$ anions were reduced to Hg and deposited on the electrode surface, and were determined with the following anodic stripping differential pulse voltammetry (ASDPV). The dependence of anodic stripping current versus concentration was linear from 1 ppb (5 nM) to 100 ppb (0.5 μM) with a regression coefficient of 0.9959.
High‐speed‐range enhancement of switched reluctance motor with continuous mode for automotive applications
Authors: Rekik M. , Besbes M. , Marchand C. , Multon B. , Loudot S. , Lhotellier D. 
Published: November 2007

AbstractThis paper describes an original method for the elaboration of control laws for the Switched Reluctance Motor (SRM) for high‐speed operation. In this case, the control optimisation relies on the choice of optimal turn‐on and turn‐off angles to ensure, in general, high global efficiency, in classical supply mode with full‐wave voltage. Then, after showing the influence of number of turns, a new supply mode called the continuous mode is described. This mode, used with a higher number of turns, allows to reduce the inverter current rating and hence silicon requirements without compromising performance at high speed. This makes the SRM competitive compared to other technologies (synchronous and induction motors). The simulation results for a 12/8 SRM are presented and compared to those for an induction motor. Copyright © 2007 John Wiley & Sons, Ltd.
Height functions for applying contact angles to 2D VOF simulations
Authors: Afkhami S. , Bussmann M. 
Published: October 2007

AbstractRecent work on a consistent representation of surface tension and on the accurate computation of interface curvature has extended the applicability of the volume‐of‐fluid, or VOF, method to surface tension‐driven phenomena. We have extended these methodologies to interfaces near solid surfaces; specifically, we show how height functions can be used to enforce a contact angle boundary condition at a contact line, for the full range of contact angles. As such, this work may be viewed as following up on the methodology of Renardy et al. (J. Comput. Phys. 2001; 171:243–263). This approach yields accurate values of curvature and the surface tension force at contact lines, values that converge with mesh refinement. The efficacy of the methodology is demonstrated using 2D examples of static fluid configurations in equilibrium and dynamic contact line phenomena that approach known equilibrium configurations. Copyright © 2007 John Wiley & Sons, Ltd.
Vessel‐depleted neck: Techniques for achieving microvascular reconstruction
Authors: Jacobson Adam S. , Eloy Jean Anderson , Park Eunice , Roman Benjamin , Genden Eric M. 
Published: October 2007

AbstractBackground.In the neck, the recipient vessels most frequently used for microsurgical reconstruction are compromised by prior surgery and radiation.Methods.We conducted a retrospective chart review of all patients who underwent microvascular reconstruction between July 2001 and June 2005. Donor vessels, vein grafts, and flap survival were examined.Results.Fourteen of 197 patients (7%) were identified with a vessel‐depleted neck. All patients had undergone a prior neck dissection and radiation (100%) or chemoradiation (42%). Free flap revascularization was achieved using the transverse cervical artery with a vein graft and a cephalic vein (4 patients), thoracoacromial artery and cephalic vein (3 patients), internal mammary artery and vein (3 patients), and inferior thyroid artery and cephalic vein (1 case). In 3 patients, the reverse flow thoracodorsal artery and cephalic vein were used to vascularize the scapular flap.Conclusion.The cephalic vein, transverse cervical, internal mammary, and thoracoacromial vessels represent reliable alternatives in the vessel‐depleted neck. © 2007 Wiley Periodicals, Inc. Head Neck, 2008
Report of a case of sinonasal undifferentiated carcinoma arising in a background of extensive nasal gliomatosis
Authors: Tetzlaff Michael T. , Liu Peter , O'Malley Bert W. , LiVolsi Virginia A. , Elder David 
Published: October 2007

AbstractBackground.Sinonasal undifferentiated carcinoma (SNUC) is a relatively rare, aggressive malignancy of adulthood. Nasal glial heterotopia is a benign congenital condition in which mature benign brain tissue develops outside the central nervous system.Methods.A 37‐year‐old man was seen with right nasal obstruction, epistaxis, and headache. Imaging showed a radiologically malignant mass lesion. Biopsy and subsequent resection were performed in the evaluation and treatment of this lesion. Histologic and immunohistochemical assessments of the biopsy and resection specimens on the pathology material classified the lesional tissue.Results.Histology and immunohistochemistry of the biopsy specimen demonstrated an SNUC that was subsequently resected following chemotherapy. In addition to SNUC, the resection specimen revealed extensive, multifocal nasal glial heterotopia (so called “nasal glioma”).Conclusions.This is the first known case in the literature in which these 2 relatively rare entities coincide. © 2007 Wiley Periodicals, Inc. Head Neck, 2008
Solitary sebaceous nevus of Jadassohn complicated by squamous cell carcinoma and basal cell carcinoma
Authors: Arshad Ahmad Ridzwan , Azman Wan S. , Kreetharan Ayadurai 
Published: October 2007

AbstractBackground.Sebaceous nevus is a benign congenital epidermal nevus. Its association with basal cell carcinoma is well known.Method.This is a case report of sebaceous carcinoma complicated by both basal cell carcinoma and squamous cell carcinoma.Results.The behavior of this tumor is very aggressive, resulting in poor prognosis.Conclusions.All sebaceous nevi should be excised early. © 2007 Wiley Periodicals, Inc. Head Neck, 2008
Supracricoid partial laryngectomies after radiation failure: A multi‐institutional series
Authors: Pellini Raul , Pichi Barbara , Ruscito Paolo , Ceroni Alberto Rinaldi , Caliceti Umberto , Rizzotto Giuseppe , Pazzaia Antonio , Laudadio Pasquale , Piazza Cesare , Peretti Giorgio , Giannarelli Diana , Spriano Giuseppe 
Published: October 2007

AbstractBackground.Radiation therapy (RT) is one of the gold standard treatments for early laryngeal cancer, and total laryngectomy is still the most applied surgical procedure after failure. Selected recurrences can be managed by supracricoid partial laryngectomies (SCPLs).Methods.A multi‐institutional retrospective analysis was carried out in 78 consecutive patients treated by SCPLs for the recurrence of glottic‐supraglottic cancer after RT. Cricohyoidoepiglottopexy was performed in 62, and cricohyoidopexy (CHP) in 16 cases.Results.Disease‐free survival at 3 and 5 years were 95.5%. Early and late postoperative complications occurred in 27% and 17.9% of cases. Decannulation and satisfactory swallowing were achieved in 97.4% of cases.Conclusions.SCPLs represent effective surgical organ‐preservation strategies in the treatment of selected recurrences after RT failure, resulting in a good local control as well as functional recovery with acceptable morbidity, despite a complication rate which is not negligible. © 2007 Wiley Periodicals, Inc. Head Neck, 2008
Long‐term survival of resectable subset after induction chemotherapy in patients with locally advanced head and neck cancer
Authors: Cho Yo‐Han , Lee Se Hoon , Kim Dong‐Wan , Wu Hong‐Gyun , Hah J. Hun , Rhee Chae‐Seo , Sung Myung‐Whun , Kim Kwang Hyun , Heo Dae Soeg 
Published: October 2007

AbstractBackground.Although meta‐analysis showed that survival improved with concurrent chemoradiation in locally advanced head and neck cancer, neoadjuvant chemotherapy is still unique, because it renders curative surgery feasible for marginally resectable head and neck cancer patients.Methods.We reviewed patients with locally advanced head and neck cancer, who had been treated with neoadjuvant chemotherapy between June 1984 and February 2001 at the Seoul National University Hospital.Results.A total of 167 patients were included. After 2 to 3 chemotherapy cycles, either surgery (38 patients) or radiation (104 patients) was conducted. Those who received surgery exhibited better survival than those who received radiation [median survival: not reached vs 33.6 months (95% CI: 22.6–44.7), p = .006]. The 5‐year and 10‐year survival rates of surgery group were 63.2% and 59.8%.Conclusion.The potential benefit of neoadjuvant chemotherapy with surgery in patients with locally advanced head and neck cancers merits further evaluation in future clinical trials. © 2007 Wiley Periodicals, Inc. Head Neck, 2008
Reconstruction of floor of mouth defects by the facial artery musculo‐mucosal flap following cancer ablation
Authors: Ayad Tareck , Kolb Frédéric , De Monés Erwan , Mamelle Gérard , Temam Stéphane 
Published: October 2007

AbstractBackground.The purpose of this study is to review our experience with the use of the facial artery musculo‐mucosal (FAMM) flap for floor of mouth (FOM) reconstruction following cancer ablation to assess its reliability, associated complications, and functional results.Methods.This was a retrospective analysis of 61 FAMM flaps performed for FOM reconstruction from 1997 to 2006.Results.No total flap loss was observed. Fifteen cases of partial flap necrosis occurred, with 2 of them requiring revision surgery. We encountered 8 other complications, with 4 of them requiring revision surgery for an overall rate of revision surgery of 10% (6/61). The majority of patients resumed to a regular diet (85%), and speech was considered as functional and/or understandable by the surgeon in 93% of the patients. Dental restoration was successful for 83% (24/29) of the patients.Conclusion.The FAMM flap is well suited for FOM reconstruction because it is reliable, has few significant complications, and allows preservation of oral function. © 2007 Wiley Periodicals, Inc. Head Neck, 2008
An investigation of the α1A‐adrenergic receptor gene and antipsychotic‐induced side‐effects
Authors: Saiz Pilar A. , Susce Margaret T. , Clark Dan A. , Kerwin Robert W. , Molero Patricio , Arranz Maria J. , de Leon Jose 
Published: October 2007

AbstractAntipsychotic treatment is hampered by the induction of side‐effects such as tardive dyskinesia (TD), weight gain, sedation and extrapyramidal side‐effects (EPS). Identification of the factors related to their development would facilitate their avoidance and the improvement of antipsychotic treatment. It has been hypothesised that genetic variants in drug targeted receptors may contribute to the development of side‐effects. In this study, we have investigated the possible influence of genetic variants (‐563‐C/T, ‐4155‐G/C and ‐4884‐A/G) of the α1A‐adrenergic receptor, an important target of atypical antipsychotic drugs, and development of side‐effects after antipsychotic medication in a sample of N = 427 US Caucasian patients. We found several marginal associations (p < 0.05) between α1A‐adrenergic genetic variants and antipsychotic‐induced side‐effects which did not reach statistical significance after corrections for multiple analyses. These results do not support a major role of α1A‐adrenergic genetic variants in obesity and other side‐effects observed after prolonged treatment with antipsychotic medications. Copyright © 2007 John Wiley & Sons, Ltd.
Decreased expression of human D‐glucuronyl C5‐epimerase in breast cancer
Authors: Grigorieva Elvira , Eshchenko Tatiana , Rykova Valentina I. , Chernakov Alexei , Zabarovsky Eugene , Sidorov Sergei V. 
Published: November 2007

AbstractD‐glucuronyl C5‐epimerase (GLCE) is one of the key enzymes in proteoglycan biosynthesis. However, nothing is known about expression and activity of the protein in cancer. In this study, we investigated GLCE expression in human breast cancer using multipex RT‐PCR, QRT‐PCR and Western‐blot assays. In total, 21 patients without malignancy and 74 patients with breast tumor were investigated. The obtained data showed that in 82–84% of human breast tumors there is either downregulation or loss of D‐glucuronyl C5‐epimerase mRNA expression and significant decrease of the protein content. In most cases (77%), GLCE expression was decreased also in the normal‐appearing tissue surrounding the tumor node but the protein amount was comparable to normal breast tissue. These findings represent the first data about involvement of human D‐glucuronyl C5‐epimerase in malignant transformation. © 2007 Wiley‐Liss, Inc.
Prevention of upper aerodigestive tract cancer in zinc‐deficient rodents: Inefficacy of genetic or pharmacological disruption of COX‐2
Authors: Fong Louise Y.Y. , Jiang Yubao , Riley Maurisa , Liu Xianglan , Smalley Karl J. , Guttridge Denis C. , Farber John L. 
Published: November 2007

AbstractZinc deficiency in humans is associated with an increased risk of upper aerodigestive tract (UADT) cancer. In rodents, zinc deficiency predisposes to carcinogenesis by causing proliferation and alterations in gene expression. We examined whether in zinc‐deficient rodents, targeted disruption of the cyclooxygenase (COX)‐2 pathway by the COX‐2 selective inhibitor celecoxib or by genetic deletion prevent UADT carcinogenesis. Tongue cancer prevention studies were conducted in zinc‐deficient rats previously exposed to a tongue carcinogen by celecoxib treatment with or without zinc replenishment, or by zinc replenishment alone. The ability of geneticCOX‐2deletion to protect against chemically‐induced forestomach tumorigenesis was examined in mice on zinc‐deficientversuszinc‐sufficient diet. The expression of 3 predictive biomarkers COX‐2, nuclear factor (NF)‐κ B p65 and leukotriene A4hydrolase (LTA4H) was examined by immunohistochemistry. In zinc‐deficient rats, celecoxib without zinc replenishment reduced lingual tumor multiplicity but not progression to malignancy. Celecoxib with zinc replenishment or zinc replenishment alone significantly lowered lingual squamous cell carcinoma incidence, as well as tumor multiplicity. Celecoxib alone reduced overexpression of the 3 biomarkers in tumors slightly, compared with intervention with zinc replenishment. Instead of being protected, zinc‐deficient COX‐2 null mice developed significantly greater tumor multiplicity and forestomach carcinoma incidence than wild‐type controls. Additionally, zinc‐deficient COX‐2−/−forestomachs displayed strong LTA4H immunostaining, indicating activation of an alternative pathway under zinc deficiency when the COX‐2 pathway is blocked. Thus, targeting only the COX‐2 pathway in zinc‐deficient animals did not prevent UADT carcinogenesis. Our data suggest zinc supplementation should be more thoroughly explored in human prevention clinical trials for UADT cancer. © 2007 Wiley‐Liss, Inc.
Why is PTEN an important tumor suppressor?
Authors: Li Li , Ross Alonzo H. 
Published: October 2007

AbstractPhosphatase and tensin homologue deleted on chromosome 10 (PTEN) was originally cloned as a tumor suppressor for brain tumors. Now it is known as a tumor suppressor for many tumor types. In this review, we ask the simple question: why is PTEN such a common and important tumor suppressor? The most obvious answer is that there are no other family members that can replace PTEN. As a result, several pathways critical for cell transformation are misregulated. The most important of these is the phosphoinositide 3‐kinase (P13K) PI3K‐Akt pathway, which has downstream effects on transcription, proliferation, cell survival, invasiveness, and angiogenesis. In addition, PTEN is linked via several mechanisms to the p53 tumor suppressor. Through p53 and additional mechanisms, loss of PTEN leads to genomic instability. Hence, PTEN is important because its loss misregulates multiple Akt‐dependent and ‐independent pathways critical for the development of cancer. J. Cell. Biochem. 102: 1368–1374, 2007. © 2007 Wiley‐Liss, Inc.
Tangency sets inPG(3, q)
Authors: Metsch K. , Storme L. 
Published: November 2007

AbstractA tangency set of PG(d,q)is a setQof points with the property that every pointPofQlies on a hyperplane that meetsQonly inP. It is known that a tangency set of PG(3,q)has at most$q^2+1$points with equality only if it is an ovoid. We show that a tangency set of PG(3,q)with$q^2-1, q\geq 19$, or$q^2$points is contained in an ovoid. This implies the non‐existence of minimal blocking sets of size$q^2-1$,$q\geq 19$, and of$q^2$with respect to planes in PG(3,q), and implies the extendability of partial 1‐systems of size$q^2-1$,$q\geq 19$, or$q^2$to 1‐systems on the hyperbolic quadric$Q^+(5,q)$. © 2007 Wiley Periodicals, Inc. J Combin Designs 16: 462–476, 2008
MCMI‐III personality complexity and depression treatment outcome following group‐based cognitive–behavioral therapy
Authors: Craigie Mark A. , Saulsman Lisa M. , Lampard Amy M. 
Published: October 2007

AbstractThis study investigated the association of personality disorder complexity to treatment outcome for depression following time‐limited group‐based cognitive–behavioral therapy. One hundred fifteen outpatients with a primary diagnosis of depression participated in the study. In this study, personality disorder complexity was determined by the degree of personality disorder comorbidity identified by the Millon Clinical Multiaxial Inventory‐III (T. Millon, 1994). As predicted, analyses revealed that increasing personality disorder complexity was related to increasing baseline symptom severity and slightly poorer end‐state functioning at posttreatment. However, results regarding clinically significant improvement and mean improvement in depression symptoms were less supportive of an association between personality disorder complexity and poorer treatment outcome. The implications of these findings for treatment planning are discussed. © 2007 Wiley Periodicals, Inc. J Clin Psychol 63: 1153–1170, 2007.
Validity of two selected‐item short forms of the WAIS‐III in an intellectually deficient sample
Authors: Alley Pamala J. , Allen Ryan A. , Leverett J. Patrick 
Published: October 2007

AbstractVarious short forms of the Wechsler Adult Intelligence Scale–Third Edition (WAIS‐III; D. Wechsler, 1997) have been investigated, but limited information is available regarding the usefulness of any WAIS‐III abbreviation with intellectually deficient individuals. Our study compared the validities of two WAIS‐III selected‐item short forms in a sample of 59 individuals with full scale IQs (FSIQs) of 79 or lower. The performance of both short forms was adequate, but the results gave a consistent edge to an adapted version of the Satz–Mogel (1962) short form in comparison to the abbreviated form by J. H. Wymer, K. Rayls, and M. T. Wagner (2003). The correlation (r = .98) of Satz–Mogel estimates with WAIS‐III FSIQ scores was slightly higher than the correlation (r = .97) for estimates from Wymer et al.'s abbreviated form, and Satz–Mogel estimates did not differ significantly from actual FSIQs. In comparison to individual classification (FSIQ > 70 versus FSIQ ≤ 70) obtained with the full WAIS‐III, the misclassification rate was somewhat lower for the Satz–Mogel short form. Although both short forms performed reasonably well, practitioners should be cautious when utilizing any short form to make decisions about individuals. © 2007 Wiley Periodicals, Inc. J Clin Psychol 63: 1145–1152, 2007.
Light and shape: A contribution to demonstrate morphological differences in diurnal and nocturnal teleosts
Authors: Pulcini Domitilla , Costa Corrado , Aguzzi Jacopo , Cataudella Stefano 
Published: October 2007

AbstractLight intensity is an important environmental factor affecting the structure of fish assemblages during the day–night cycle. Light influences how organisms perceive their environment, modulating their intraspecific and interspecific relationships. The relationship between light intensity variations and biological cycles should be observed at the level of organismal morphology. In this study the relationship between activity rhythms, thus light intensity experienced by fish in the period of major activity and external morphology, have been investigated. The morphological traits of 97 selected fish species were compared in order to determine the existence of a common morphological plan in agreement with their diurnal or nocturnal activity rhythm. Species sorting was performed by maximizing the diversity of activity rhythm, habitat choice, ecology, and trophic habits within the same family, to assess the importance of the day–night cycle on species morphology in relation to other environmental features. The morphological characters selected for the geometric morphometric analysis were body profile and the position of mouth, eye, pelvic, pectoral, dorsal, and caudal fin. The present analysis allowed different consensus forms for nocturnal and for diurnal species to be identified. Two‐block Partial Least Squares analysis was then performed for the purpose of modeling the covariation between the form and two important external variables (ecology and activity). J. Morphol., 2008. © 2007 Wiley‐Liss, Inc.
Articular cartilage in the knee joint of the African elephant, Loxodonta africana, Blumenbach 1797
Authors: Egger Gunter F. , Witter Kirsti , Weissengruber Gerald , Forstenpointner Gerhard 
Published: October 2007

AbstractKnee joints of one adult and three juvenile African elephants were dissected. The specific features of the articular cartilage with particular reference to matrix components were studied by light and electron microscopy and immunohistochemistry. The elephant knee joint cartilage contains an unusually low concentration of proteoglycans resulting in rather eosinophilic staining properties of the matrix. The very thick collagen fibers of the cartilage possibly represent collagen I. Except for the different thickness of cartilage at the weight‐bearing surfaces of femur (∼6.7 mm) and tibia (∼11.2 mm) in juvenile elephants, light and electron microscopy did not reveal distinct topographical differences in cartilage structure, perhaps because of the high congruency of the articulating surfaces and resulting uniform load distribution in the knee. The number of cell profiles per section area of both femoral (∼950 cell profiles/mm2) and tibial cartilage (∼898 cell profiles/mm2) was low, indicating excessive matrix production by the chondrocytes during cartilage development. These unique properties could be a result of the enormous compressive load resting on the elephant knee. Maintenance of the equilibrium between biological function and resistance to compression seems to be crucial in the elephant knee joint cartilage. Any disturbance that interferes with this equilibrium appears to lead to arthrotic alterations, as particularly seen in captive elephants. J. Morphol., 2008. © 2007 Wiley‐Liss, Inc.