bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Lebanese press in opposition to the French in 1943: The (??) newspaper, two question marks as a model
Authors: Al Zuhairi Assis. Prof. Dr. Hussein Abdel Hussein Abbas , Jabr Ass,Prof. Dr. Haider Abdel-Aali 
Published: March 2024

The Lebanese press played a major role in directing Lebanese public opinion; As the only carrier of political, economic and social events and developments in Lebanon, this press, whose roots go back to the mid-nineteenth century, was able, thanks to its extensive experience, to control the Lebanese with their various orientations, tendencies and sects, and the press was able to form a strong opposition to the French trends, especially during the crisis The eleventh of November 1943, whose effects were clearly reflected on the developments of the Lebanese political situation in general, and on the French in particular. The subject of the Lebanese press in opposition to the French was not previously discussed by researchers in their academic and scientific studies, which makes it of great importance to shed light on it, and herein lies the importance of the subject.
In this research, we focused on (the Lebanese press opposed to the French in 1943: the newspaper (??) two question marks as a model), which was chosen in 1943; As the year in which the newspaper appeared for the first time, as a result of political developments in Lebanon, after the French authorities suspended all newspapers and publications in Lebanon, following the declaration of martial law in November of that year. The researcher stopped in 1943; Having witnessed the abolition of all the laws issued by the French authorities in Lebanon by the Lebanese Parliament, including the law of disabling the press and publications, as well as the end of the Lebanese crisis, the return of political life to normal, and the extinction of the newspaper whose name was later changed to Al-Aqdam newspaper. This important media outlet appeared with the crisis and ended with its end, and it was the medium that conveyed to all the Lebanese the course of political events in their country after all the newspapers stopped, and it is issued in secret.
PERCEPTIONS TOWARDS THE INDEPENDENT AUDITING PROFESSION
Authors: Şıtak Başak , Yeşil Salih 
Published: March 2024

Çalışmanın amacı, Adana ve Osmaniye ilinde faaliyet gösteren bağımsız denetçilerin denetçilik
mesleğine yönelik algılarının tespit edilmesidir. Çalışmanın bir diğer amacı ise bu konuya yönelik
algıların demografik değişkenler açısından farklılık gösterip göstermediğini belirlemektir. Çalışmanın
amaçlarına ulaşmak için Frekans, T Testi, ANOVA ve Tukey Post Hoc testi yöntemlerinden
faydalanılmıştır. Elde edilen veriler incelendiğinde; denetimin kayıt dışı ekonomiyi önleyebilmek
açısından kilit rol üstlendiği, mali denetçilik mesleğini icra ederken, mali müşavirlikte kazandıkları
gelirden daha fazla bir gelir elde edebilecekleri düşündükleri ve 15 yıllık mesleki tecrübeye sahip olan
mali müşavirlerin uygulamalı mesleki eğitimden muaf tutulmalarına olumsuz yaklaştıkları
görülmüştür. Bununla birlikte bağımsız denetçilerin mesleğe yönelik algıları unvanları, eğitim
durumları, yaşları ve deneyim süreleri açısından değişkenlik göstermektedir. Çalışmanın ele alınan
perspektiften daha önce incelenmemiş olması literatüre sağlayacağı katkıyı destekler niteliktedir.
Peningkatan Potensi Desa Wisata Melalui Pemberdayaan Masyarakat Di Desa Perlang, Kabupaten Bangka Tengah
Authors: Tamisha Chery , Fitriani Annisa , Silvia  
Published: March 2024

For four months, Perlang Village, Lubuk Besar District, Central Bangka Regency, became a place of service for the KKNT program for Bangka Belitung University students. There are two types of these activities: non-programmed work programs and programmed work programs. Training is provided as part of community service activities in Perlang village with the aim of improving the economy and creativity of the community, especially MSMEs. The next task is cultivating palm mushrooms and choosing a new snorkeling location for village visitors. Additional activities carried out are activities that are based on meeting community needs, such as carrying out social service, participating in independence events and being a ceremonial officer, taking part in the Lake Pading 2 festival, delivering educational material and teaching in line, providing counseling at Posyandu, and creating photo spots.
The use of images in the promotion of health behaviors | Fact-sheets collection from the Portuguese COVID-19 pandemic Task Force on Behavioral Sciences
Authors: Santos Ricardo R. , Santos Osvaldo , De Matos Margarida Gaspar 
Published: March 2024

The use of images is highly frequent in science and health communication, and it is usually considered to be very effective to transmit health messages. Although not so much attention has been paid to measuring the effects of using visual elements in public health communication, images can indeed contribute to increasing effectiveness in promoting adherence to health behaviors. The choice between images that activated negative emotions, such as fear or threat, versus images that induce positive emotions, such as emotions resulting from social support, or rather emotional-neutral images, needs to be grounded in evidence about how emotional arousal may impact health-oriented decisions. This fact sheet was developed to provide easy-to-use scientific pieces of evidence about the use of images for health promotion to stakeholders involved in public health decisions.
Career transition of dancers in Portugal: an exploratory study supporting the need for a program for development and career transition in dance
Authors: Borges de Castro Fabíola 
Published: March 2024

Background: The subject of career transition for dancers continues to be a challenging issue to tackle. Consequently, dancers are mostly left alone to deal with this crucial transition, one that also determines the quality of their lives after dance. Goals: Main finality of this research study was to understand and offer guidance in the career transition experiences of professional dancers in Portugal and to propose a development and career transition program in dance that allows effective intervention to help dancers in their transition process. Main goal was to characterize how dancers perceive their career transition processes.Methods: The study follows a qualitative approach, with data collection throw semi-structured individual interviews to professional dancers (from both genders) at different moments of career. Thematic analysis was conducted for the complete corpus, with codes emerging from the collected data (no a-priori coding system).Results: Six key themes and a total of 34 sub-themes were identified. Dancers referred to feel unsupported and alone and, consequently, to experience significant psychological challenges when faced with a career transition. Most specifically, without adequate guidance, dancers reported to feel unprepared for their future. None of the interviewed dancers was aware of initiatives available to support dance career transition in Portugal. They were aware, however, of the existence of programs in other countries and expressed a need for such support in Portugal.Discussion: . It can be concluded from the above that this research validates the need for a development and career transition program in the Portuguese dance community, one that aims to soften and/or eradicate the challenges associated with a dancer’s transition from active performer into a dance-related or other career. Collected data support the need for outlining a training and supportive program that provides dancers with tools to enable a healthier and harmonious experience of transitioning beyond performance. Keywords: career transition; career development; dance; dancers; intervention program
Adjustment and perceived needs of cancer survivors: a qualitative exploratory study in a Portuguese island region
Authors: Sousa Marina , Canavarro Maria Cristina , Cabral Joana , Barreto Carvalho Célia , Moreira Helena 
Published: March 2024

Background: Cancer survivors from rural or isolated areas may experience psychosocial adjustment issues and needs following treatments. The adjustment and the perceived needs of cancer survivors in the Azores have not been investigated. Goals: To explore the adjustment to survivorship and perceived needs of cancer survivors from a Portuguese archipelago region.Methods: Cancer survivors from São Miguel Island (Azores archipelago) took part in this qualitative exploratory study. Three focus groups were carried out, which were transcribed, coded through thematic analysis, and analyzed using NVivo 12.Results: The sample comprised twenty-two cancer survivors. Five main themes emerged: 1) Current adjustment to diagnosis; 2) Barriers to current adjustment; 3) Promoters of current adjustment; 4) Post-diagnostic growth; and 5) Perceived needs and suggestions for improvement. The results revealed that the factors influencing cancer survivors´ adjustment and their perceived needs are similar to those of survivors from other rural or isolated regions. However, some differences were found, such as the perceived trauma related to the follow-up spaced-out period and the displacement to Portugal mainland to perform cancer therapy as a promoter of adjustment in survivorship. Beyond the financial and social concerns, the psychosocial support and continuity of care needs were also expressed by cancer survivors.Discussion: Assessing and monitoring survivors' needs during different stages of the disease could inform health and psychosocial care providers on how to better support cancer survivors from the Azores, preparing them for survivorship. A multidisciplinary approach which recognizes cancer survivors’ difficulties and unmet needs can promote optimal care delivery, improving their adjustment.
Model of the external force field for the protein folding process—the role of prefoldin
Authors: Roterman Irena , Stapor Katarzyna , Konieczny Leszek 
Published: March 2024

Introduction: The protein folding process is very sensitive to environmental conditions. Many possibilities in the form of numerous pathways for this process can—if an incorrect one is chosen—lead to the creation of forms described as misfolded. The aqueous environment is the natural one for the protein folding process. Nonetheless, other factors such as the cell membrane and the presence of specific molecules (chaperones) affect this process, ensuring the correct expected structural form to guarantee biological activity. All these factors can be considered components of the external force field for this process.Methods: The fuzzy oil drop-modified (FOD-M) model makes possible the quantitative evaluation of the modification of the external field, treating the aqueous environment as a reference. The FOD-M model (tested on membrane proteins) includes the component modifying the water environment, allowing the assessment of the external force field generated by prefoldin.Results: In this work, prefoldin was treated as the provider of a specific external force field for actin and tubulin. The discussed model can be applied to any folding process simulation, taking into account the changed external conditions. Hence, it can help simulate the in silico protein folding process under defined external conditions determined by the respective external force field. In this work, the structures of prefoldin and protein folded with the participation of prefoldin were analyzed.Discussion: Thus, the role of prefoldin can be treated as a provider of an external field comparable to other environmental factors affecting the protein folding process.
Effects of Bacillus coagulans TBC169 on gut microbiota and metabolites in gynecological laparoscopy patients
Authors: Gao Weiqi , Yan Ya , Guan Zhaobo , Zhang Jingmin , Chen Weihong 
Published: March 2024

ObjectiveThe primary objective of this study is to investigate the mechanism by which Bacillus coagulans TBC169 accelerates intestinal function recovery in patients who have undergone gynecological laparoscopic surgery, using metabolomics and gut microbiota analysis.MethodsA total of 20 subjects were selected and randomly divided into two groups: the intervention group (n = 10) receiving Bacillus coagulans TBC169 Tablets (6 pills, 1.05 × 108 CFU), and the control group (n = 10) receiving placebos (6 pills). After the initial postoperative defecation, fecal samples were collected from each subject to analyze their gut microbiota and metabolic profiles by high-throughput 16S rRNA gene sequencing analysis and untargeted metabonomic.ResultsThere were no statistically significant differences observed in the α-diversity and β-diversity between the two groups; however, in the intervention group, there was a significant reduction in the relative abundance of unclassified_Enterobacteriaceae at the genus level. Furthermore, the control group showed increased levels of Holdemanella and Enterobacter, whereas the intervention group exhibited elevated levels of Intestinimonas. And administration of Bacillus coagulans TBC169 led to variations in 2 metabolic pathways: D-glutamine and D-glutamate metabolism, and arginine biosynthesis.ConclusionThis study demonstrated that consuming Bacillus coagulans TBC169 after gynecological laparoscopic surgery might inhibit the proliferation of harmful Enterobacteriaceae; mainly influence 2 pathways including D-glutamine and D-glutamate metabolism, and arginine biosynthesis; and regulate metabolites related to immunity and intestinal motility; which can help regulate immune function, maintain intestinal balance, promote intestinal peristalsis, and thus accelerate the recovery of intestinal function.
Therapeutic potential of tyrosine-protein kinase MET in osteosarcoma
Authors: Zeng Ming , Liu Can , Gong Haoli , Tang Zhongwen , Wen Jie , Wang Sisi , Xiao Sheng 
Published: March 2024

Osteosarcoma, the most prevalent primary bone tumor in children and young adults, can often be successfully treated with standard chemotherapy and surgery when diagnosed at an early stage. However, patients presenting with metastases face significant challenges in achieving a cure. Despite advancements in classical therapies over the past few decades, clinical outcomes for osteosarcoma have not substantially improved. Recently, there has been increased understanding of the biology of osteosarcoma, leading to the identification of new therapeutic targets. One such target is MET, a tyrosine kinase receptor for Hepatocyte Growth Factor (HGF) encoded by the MET gene. In vitro and in vivo studies have demonstrated that the HGF/MET pathway plays a crucial role in cancer growth, invasion, metastasis, and drug resistance across various cancers. Clinical trials targeting this pathway are already underway for lung cancer and hepatocellular carcinoma. Moreover, MET has also been implicated in promoting osteosarcoma progression. This review summarizes 3 decades’ worth of research on MET’s involvement in osteosarcoma and further explores its potential as a therapeutic target for patients with this disease.
suMRak: a multi-tool solution for preclinical brain MRI data analysis
Authors: Ister Rok , Sternak Marko , Škokić Siniša , Gajović Srećko 
Published: March 2024

IntroductionMagnetic resonance imaging (MRI) is invaluable for understanding brain disorders, but data complexity poses a challenge in experimental research. In this study, we introduce suMRak, a MATLAB application designed for efficient preclinical brain MRI analysis. SuMRak integrates brain segmentation, volumetry, image registration, and parameter map generation into a unified interface, thereby reducing the number of separate tools that researchers may require for straightforward data handling.Methods and implementationAll functionalities of suMRak are implemented using the MATLAB App Designer and the MATLAB-integrated Python engine. A total of six helper applications were developed alongside the main suMRak interface to allow for a cohesive and streamlined workflow. The brain segmentation strategy was validated by comparing suMRak against manual segmentation and ITK-SNAP, a popular open-source application for biomedical image segmentation.ResultsWhen compared with the manual segmentation of coronal mouse brain slices, suMRak achieved a high Sørensen–Dice similarity coefficient (0.98 ± 0.01), approaching manual accuracy. Additionally, suMRak exhibited significant improvement (p = 0.03) when compared to ITK-SNAP, particularly for caudally located brain slices. Furthermore, suMRak was capable of effectively analyzing preclinical MRI data obtained in our own studies. Most notably, the results of brain perfusion map registration to T2-weighted images were shown, improving the topographic connection to anatomical areas and enabling further data analysis to better account for the inherent spatial distortions of echoplanar imaging.DiscussionSuMRak offers efficient MRI data processing of preclinical brain images, enabling researchers' consistency and precision. Notably, the accelerated brain segmentation, achieved through K-means clustering and morphological operations, significantly reduces processing time and allows for easier handling of larger datasets.
U-NTCA: nnUNet and nested transformer with channel attention for corneal cell segmentation
Authors: Zhang Dan , Zhang Jing , Li Saiqing , Dong Zhixin , Zheng Qinxiang , Zhang Jiong 
Published: March 2024

BackgroundAutomatic segmentation of corneal stromal cells can assist ophthalmologists to detect abnormal morphology in confocal microscopy images, thereby assessing the virus infection or conical mutation of corneas, and avoiding irreversible pathological damage. However, the corneal stromal cells often suffer from uneven illumination and disordered vascular occlusion, resulting in inaccurate segmentation.MethodsIn response to these challenges, this study proposes a novel approach: a nnUNet and nested Transformer-based network integrated with dual high-order channel attention, named U-NTCA. Unlike nnUNet, this architecture allows for the recursive transmission of crucial contextual features and direct interaction of features across layers to improve the accuracy of cell recognition in low-quality regions. The proposed methodology involves multiple steps. Firstly, three underlying features with the same channel number are sent into an attention channel named gnConv to facilitate higher-order interaction of local context. Secondly, we leverage different layers in U-Net to integrate Transformer nested with gnConv, and concatenate multiple Transformers to transmit multi-scale features in a bottom-up manner. We encode the downsampling features, corresponding upsampling features, and low-level feature information transmitted from lower layers to model potential correlations between features of varying sizes and resolutions. These multi-scale features play a pivotal role in refining the position information and morphological details of the current layer through recursive transmission.ResultsExperimental results on a clinical dataset including 136 images show that the proposed method achieves competitive performance with a Dice score of 82.72% and an AUC (Area Under Curve) of 90.92%, which are higher than the performance of nnUNet.ConclusionThe experimental results indicate that our model provides a cost-effective and high-precision segmentation solution for corneal stromal cells, particularly in challenging image scenarios.
Deficiency of the paternally-expressed imprinted Peg3 gene in mice has sexually dimorphic consequences for offspring communication and social behaviour
Authors: Tyson Hannah R. , Harrison David J. , Higgs Mathew J. , Isles Anthony R. , John Rosalind M. 
Published: March 2024

IntroductionImprinted genes are expressed from one parental allele as a consequence of epigenetic processes initiated in the germline. Consequently, their ability to influence phenotype depends on their parent-of-origin. Recent research suggests that the sex of the individual expressing the imprinted gene is also important. We have previously reported that genetically wildtype (WT) dams carrying and caring for pups mutant for PEG3 exhibit anxiety-like behaviours and their mutant pups show a reduction in ultrasonic vocalisation when separated from their mothers. Sex-specificity was not examined.MethodsWT female mice were mated with WT, heterozygous Peg3−/+ or homozygous Peg3−/− studs to generate all WT (control), 50:50 mixed or 100% mutant litters, respectively, followed by behavioural assessment of both dams and their pups.ResultsWe reproduced our original finding that WT dams carrying and caring for 100% mutant litters exhibit postpartum anxiety-like symptoms and delayed pup retrieval. Additionally, these WT dams were found to allocate less time to pup-directed care behaviours relative to controls. Male Peg3-deficient pups demonstrated significantly reduced vocalisation with a more subtle communication deficit in females. Postweaning, male mutants exhibited deficits across a number of key social behaviours as did WT males sharing their environment with mutants. Only modest variations in social behaviour were detected in experimental females.DiscussionWe have experimentally demonstrated that Peg3 deficiency confined to the offspring causes anxiety in mouse mothers and atypical behaviour including deficits in communication in their male offspring. A male-specific reduction in expression PEG3 in the fetally-derived placenta has previously been associated with maternal depression in human pregnancy. Maternal mood disorders such as depression and anxiety are associated with delays in language development and neuroatypical behaviour more common in sons. Peg3 deficiency could drive the association of maternal and offspring behavioural disorders reported in humans.
Case report: Urachal perivascular epithelioid cell tumor
Authors: Liu Mengru , Liang Pan , Lyu Dongbo , Zhu Bingbing , Gao Jianbo 
Published: March 2024

BackgroundUrachal tumors are rare in clinical practice, among which urachal adenocarcinoma is the most common. In this study, we report a rare case of urachal perivascular epithelioid cell tumor to improve our understanding of the disease.Case presentationA 26-year-old male patient was hospitalized for lower abdominal pain. The US showed a hypoechoic mass measuring 26mm × 18mm in the superior aspect of the bladder. MRI showed an irregular mass located anterior to the bladder roof, near the midline. The tumor exhibited hypointense on T1WI and heterogeneous hyperintense on T2WI. Additionally, contrast-enhanced T1-weighted imaging revealed obvious ring enhancement of the tumor. The patient underwent surgical resection of the urachal tumor, with subsequent pathological examination revealing a diagnosis of urachal PEComa. Following surgery, the patient underwent regular follow-up assessments, with no evidence of recurrence or metastasis observed after three and a half years.ConclusionsUrachal PEComa is a rare mesenchymal tumor that presents challenges in diagnosis through imaging and clinical symptoms. Definitive diagnosis relies on pathological and immunohistochemical analysis. Due to the rarity of urachal PEComa, prognosis assessment necessitates long-term follow-up and evaluation of more cases.