bluuebunny/crossref_metadata_2025_split huggingface dataset:
Randomized Controlled Trial of Intravenous Ferric Carboxymaltose vs Oral Iron to Treat Iron Deficiency Anemia After Variceal Bleed in Patients With Cirrhosis
Authors: Tabish Mohammad , Agarwal Samagra , Gopi Srikanth , Rana Randeep , Ahmed Syed , Gunjan Deepak , Sharma Sanchit , Saraya Anoop 
Published: March 2024

INTRODUCTION:
Limited evidence exists on the optimal strategy to correct iron deficiency anemia after variceal bleeding (VB) in cirrhosis. This trial compared the efficacy and safety of intravenous ferric carboxymaltose (IV-FCM) with those of oral iron therapy in this cohort.

METHODS:
In this open-label, single-center, randomized controlled trial, eligible patients with hemoglobin <10 g/dL and iron deficiency (ferritin <100 ng/mL) after VB received either IV-FCM (1,500–2,000 mg) divided into 2 doses (n = 48) or oral carbonyl iron (100 mg elemental iron/day) (n = 44) for 3 months. The primary outcome was change in hemoglobin at 3 months. Secondary outcomes included improvement in anemia (last hemoglobin >12 g/dL), normalization of iron stores (ferritin >100 ng/mL), liver-related adverse events, adverse drug reactions, and changes in quality of life (CLDQOL questionnaire).

RESULTS:
Baseline characteristics, including median Child-Turcotte-Pugh score 7 (interquartile range [IQR] 6–9), Model for End-Stage Liver Disease score 12 (IQR 10–17), blood hemoglobin (8.25 ± 1.06 g/dL), and ferritin (30.00 ng/mL [15.00–66.50]), were comparable in both arms. The median increase in hemoglobin at 3 months in the IV and oral arms was 3.65 g/dL (IQR 2.55–5.25) and 1.10 g/dL (IQR 0.05–2.90 g/dL) (P < 0.001), respectively. Iron stores normalized in 84.6% and 21% of the IV and oral arms, respectively (P < 0.001). Anemia improved in 50% and 21.9% in the IV and oral arms, respectively (P < 0.009). Patients in the IV arm showed a significant improvement in all domains of CLDQOL. Liver-related adverse events were comparable in both arms. Transient mild/moderate hypophosphatemia developed in 43% of patients receiving IV-FCM.

DISCUSSION:
Intravenous iron replacement is efficacious and safe to treat iron deficiency anemia after VB in patients with cirrhosis.
Corrosion inhibition of carbon steel in perchloric acid by potassium iodide
Authors: Attar Tarik , Benchadli Abbes , Choukchou-Braham Esma 
Published: March 2024

Corrosion processes are responsible for numerous losses mainly in the industrial scope. It is clear that the best way to combat it is pre-vention. The effect of temperature on the corrosion behavior of carbon steel was studied by mass loss measurements in the temperature range 293â€“333 K. The inhibition efficiency increases with increasing temperature. The inhibitor showed 97.98 % inhibition efficiency at 1.10-3 M concentration of iodide potassium in 1 M perchloric acid solutions. The values of activation energy (Ea), enthalpy of activation (Î”Ha) and entropy of activation (Î”Sa), free energy of adsorption (Î”Gads), enthalpy of adsorption (Î”Hads) and entropy of adsorption (Î”Sads) were calculated. The adsorption of this inhibitor on carbon steel surface obeys Langmuir adsorption isotherm.Â Â
Proposing a procedure for multi-objective optimization of cascade thermoelectric coolers to achieve maximum cooling capacity and COP
Authors: Hadidi Amin 
Published: March 2024

Abstract
A novel approach is proposed for optimal designing two-stage thermoelectric coolers using the biogeography-based optimization algorithm. For the comprehensiveness of the research, both types of two-stage coolers, including electrically serial and separated stages, have been investigated. Using the proposed procedure, first by selecting the most important performance parameters of the cooler, i.e. COP and the cooling capacity as objective functions, the efficiency and the validity of the approach are proved by comparing the results with results of the previous researchers. In all the examined cases, the proposed approach has led to the enhancing of the cooler performance. The results of single-objective optimization showed that using the proposed method, the cooling capacity and COP can be improved up to 17 % and 8.5 % compared to the previous designs, respectively. In the following, multi-objective optimization of thermoelectric coolers is conducted, taking into account both the objectives of the COP and the cooling capacity. Finally, Pareto optimal solutions and the exergetic efficiency of the optimized cooler were calculated for different values of the weight factor of the multi-objective function. The results of multi-objective optimization showed that by increasing the COP weight factor in the objective function, the exergetic efficiency of the refrigeration system enhances.
Second twin outcome at birth: retrospective analysis in a single tertiary centre in Malaysia
Authors: Rahman Rahana Abd , Mohammed Nawi Azmawati , Ishak Shareena , Balaraman Kartik , Abu Mohamad Azrai , Abd Azman Siti Hajar , Kalok Aida Hani , Mohamed Ismail Nor Azlin , Mahdy Zaleha Abdullah , Ahmad Shuhaila 
Published: March 2024

Abstract

Objectives
To investigate factors associated with outcome of second twin during labour.

Methods
The study was a retrospective cohort study in a single tertiary centre in Malaysia from 2014 until 2018 involving all twin pregnancies delivered at or more than 24 weeks of gestation.

Results
Total of 409 twin pregnancies were included. Dichorionic twin comprises of 54.5 % (n=223) and 45.5 % (n=186) are monochorionic. Women with dichorionic pregnancies are significantly older (p<0.001), have more pre-existing medical disorders (p=0.011) and fetal structural anomalies (p=0.009). Monochorionic pregnancies are significantly more amongst Malay (p=0.01) and conceived spontaneously (p<0.001). There are significantly more fetuses both in cephalic presentation (p=0.026), birthweight discrepancy more than 20 % (p=0.038) and shorter mean inter-twin delivery duration (p=0.048) in monochorionic pregnancies. Second twin delivered with Apgar score <7 is significantly more in dichorionic pregnancies (p=0.006). The second twin is associated with lower birthweight, small for gestational age and arterial cord pH<7.25. Within the group of women who delivered both fetuses vaginally, there was significantly more second twins with intertwin delivery duration less than 30 min who were delivered vaginally without instrumentation (p=0.018). There was significantly more second twin with intertwin delivery duration of 30 min and more with arterial cord pH<7.25 (p=0.045). Those who delivered spontaneously had inter-twin delivery duration within 15–29 min. The outcome of second twin is not influenced by type of twin, gestational age at delivery, inter-twin delivery duration, mode of delivery and presentation at birth.

Conclusions
The neonatal outcome for the second twin at birth is not influenced by type of twin, gestational age at delivery, inter-twin delivery duration, mode of delivery and presentation at birth in a cohort managed with non-active management of the second twin in Malaysia.
Unleashing the potential: super-resolution microscopy as the key to advanced mitochondrial research
Authors: Li Xiaoyu , He Miao , Huang Xiaoshuai 
Published: March 2024

Abstract
Investigating the fine structure of mitochondria and their dynamic interactions with other organelles is crucial for unraveling the mechanisms underlying mitochondrial-related diseases. The development of super-resolution techniques has provided powerful visualization tools for mitochondrial research, which is significant for investigating mitochondrial cristae structure, the localization of mitochondrial-related protein complex, and the interactions between mitochondria and other organelles. In this perspective, we introduce several advanced super-resolution techniques and their applications in mitochondrial research, and discuss the potential roles these techniques may play in future studies of mitochondria.
The Environment (Air Quality and Soundscapes) (Wales) Act 2024
Authors: McVay Martin 
Published: March 2024

Abstract
The Welsh Government’s policy on noise and soundscape is underpinned by two key pieces of legislation: the Well-being of Future Generations (Wales) Act 2015, and the Environment (Air Quality and Soundscapes) (Wales) Act 2024. The former established our national well-being/sustainable development goals and five ways of working that public bodies should follow in order to achieve them. The latter requires Welsh Ministers to set out their soundscape policies in a national strategy and requires public authorities to have regard to the policies in that strategy when carrying out their functions. The intent of this article is to raise international awareness amongst soundscape researchers as to how one devolved nation has incorporated the concept of soundscape in its policies and legislation and hopefully encourage the further development and dissemination of soundscape assessment and design tools that enable practitioners to better implement those policies.
Benchmarking the aircraft noise mapping package developed for a unified urban environmental modelling tool
Authors: Ang Linus Yinn Leng , Cui Fangsen , Poh Hee Joo 
Published: March 2024

Abstract
In densely populated cities, residents living near aerodromes may experience heightened exposure to aircraft noise. With hybrid work arrangement, authorities have observed a rise in the number of complaints filed by residents affected by aircraft noise. In view of this problem, urban planners are now placing even more emphasis on exploring solutions that can manage aircraft noise in new and existing residential areas. To achieve this objective, urban planners usually rely on external acoustic consultants to generate noise maps using commercial software. However, urban planners may need to quickly evaluate potential noise issues in the neighbourhood so that noise management strategies can be brainstormed in advance. In this article, we present the development and benchmarking of a package designed to easily generate aircraft noise maps via simplified procedures and a reduced amount of input data, with acceptable accuracy in the results. These benefits distinguish our developed package from commercial software. Our developed package was eventually integrated into an in-house-developed unified urban environmental modelling tool that aims to help urban planners design more liveable and sustainable residential towns in an intuitive and quick manner.
Sustainable approach for the treatment of dye-containing wastewater – a critical review
Authors: Kumar Diwakar , Gupta Sunil Kumar 
Published: March 2024

Abstract
In the world’s rapidly expanding economy, textile industries are recognized as a substantial contributor to economic growth, but they are one of the most significant polluting industrial sectors. Dye-contaminated water sources can pose serious public health concerns, including toxicity, mutagenicity, and carcinogenicity among other adverse health effects. Despite a limited understanding of efficacious decolorization methodologies, the pursuit of a sustainable strategy for the treatment of a wide spectrum of dyes remains a formidable challenge. This article conducted an exhaustive review of extant literature pertaining to diverse physical, chemical, biological, and hybrid processes with the aim of ascertaining their efficacy. It also elucidates the advantages and disadvantages, cost considerations, as well as scalability impediments of the treatment methodologies, thereby facilitating the identification of optimal strategies for establishing techno-economically efficient processes in the sustainable handling of these effluents. The hybrid configuration exhibited superior efficiency and was documented to surmount the limitations and constraints inherent to individual techniques. The study also revealed that most of the proven and established dye removal techniques share a common limitation viz., the generation of secondary pollution (i.e., sludge generation, toxic intermediates, etc.) to the ecosystem.
Pyrane-based cembranoid and 2-dehydro-4-peroxy-sarcophine: two new diterpenes from Sarcophyton glaucum
Authors: Shaaban Mohamed , Ghani Mohamed A. 
Published: March 2024

Abstract
Soft corals, particularly Sarcophyton sp. are rich in metabolites with variety of biological activities. In this study, a pyran-based 9-exo-methylene-10-hydroxy-sarcotrocheliol (1) and 2-dehydro-4-peroxy-sarcophine (2), two new cembranoide diterpenes, were isolated together with 9-hydroxy-10,11-dehydro-sarcotrocheliol, sarcotrocheliol, sarcotrocheliol acetate, sarcophine, (+)-7α,8β-dihydroxydeepoxysarcophine, (±)-sarcophytonine B, and peridinin from the organic extract of Sarcophyton glaucum collected at the coasts of Hurghada, Egypt. The structures of the new diterpenes 1–2 were identified based on cumulative analyses of HRESIMS and NMR (1D/2D NMR) spectra. The relative configurations of both compounds were verified by NOESY spectra and comparison with our recently reported analogues. The compounds showed no antimicrobial activity against a set of diverse tested microorganisms.
Alternativas con perspectiva feminista y alcance internacional a la institucionalización de las mujeres que sufren violencia en las casas de acogida
Authors: Moriana Mateo Gabriela 
Published: March 2024

El objetivo de este artículo es realizar una reflexión desde la perspectiva feminista y alcance internacional sobre las alternativas comunitarias a la institucionalización de las mujeres que sufren violencia en las casas de acogida. Para ello, se ha entrevistado a cuatro informantes clave. Respecto a los resultados, las principales cuestiones señaladas son: i) las dificultades para pensar las alternativas; ii) las políticas públicas para las mujeres deben ser globales; iii) la necesidad de mirar y analizar la violencia contra las mujeres de forma integral; iv) la necesaria coordinación de todos recursos y programas de violencia contra las mujeres; v) la necesaria reflexión crítica respecto a lo que se ha hecho y tiene que hacer; vi) la necesidad de medidas cautelares más duras y casas de acogida para los agresores; vii) la responsabilidad de la fiscalía y policía en la protección; viii) la utilidad de las casas de acogida en casos concretos y por muy breves periodos de tiempo; ix) la alternativa comunitaria a la institucionalización; x) la creación de programas para las egresadas y para las que no quieran ingresar en las casas de acogida; xi) implicar a las supervivientes de la violencia en la respuesta institucional y ruta crítica. Así, a modo de conclusiones, es preciso señalar la necesidad de seguir reflexionando e iniciar el proceso de implementación de programas comunitarios de largo plazo para acompañar a las mujeres que sufren violencia desde la dependencia hasta la autonomía sin imponer la institucionalización como única forma de ayuda y protección.
Nilai Budaya Tari Mendaiq di Lombok Timur : Kajian Semiotika Susan K. Langer
Authors: Masrurroh Miftahul , Yuliatin Riyana Rizki , Rahman Ummi Risti Ayuni , Murcahyanto Hary 
Published: March 2024

Perempuan-perempuan Sasak pada zaman dahulu yang menggantungkan kehidupannya dari sumber alam yaitu air dapat tercipta sebagai sebuah karya seni yang ada pada sebuah tarian yaitu tari Mendaiq. Penelitian ini bertujuan untuk menganalisis bentuk gerak dan makna serta nilai-nilai budaya dalam tari Mendaiq. Untuk menelaah dan memecahkan permasalahan tersebut digunakan teori gerak tari dan teori simbol Susanne K. Langer yaitu simbol diskursif dan simbol presentational. Penelitian ini merupakan penelitian kualitatif deskriptif dengan dengan pendekatan grounded theory. Pendekatan ini digunakan untuk menentukan atau menguatkan suatu teori berdasarkan fakta. Data primer dalam penelitian ini berupa video, foto dan hasil wawancara kepada informan. Teknik pengumpulan data dilakukan dengan cara observasi partisipatif, wawancara mendalam dan dokumentasi. Analisis data dilakukan dengan tiga langkah yakni reduksi data, penyajian data, dan penarikan kesimpulan. Hasil penelitian menunjukkan bahwa Tari Mendaiq memiliki empat belas bentuk gerak yang mengandung elemen ruang, waktu dan tenaga. Makna diskursif terdiri dari sembilan gerak tari dan simbol presentational terdiri dari lima gerakan. Nilai-nilai budaya yang terkandung dalam Tarian Mendaiq berpijak pada prinsip hidup orang sasak yaitu tindih, mali’, likar napak, merang dan sukur sabar. Simpulan penelitian menunjukkan bahwa Tari Mendaiq merupakan tari kreasi yang menjadi salah satu ciri kebudayaan masyarakat Sasak
Discrimination, freedom of expression and two concepts of liberty: Assessing European legislation criminalizing hate speech
Authors: Stajnko Jan , Siter Daniel , Tomažič Luka Martin 
Published: March 2024

AbstractHate speech has been linked to categorization, stereotyping and discrimination challenges. Moreover, it presents an intersection of criminal law, criminology, philosophy of law and psychology. The authors analyse discrimination and freedom of expression in the legal framework of the European Union and in the practice of the European Court of Human Rights. They apply Berlin's two concepts of liberty, namely positive and negative liberty, to research the nature of European jurisprudence and the selected legislative frameworks. The choice between conceptions of essential moral and political values, such as positive and negative liberty, has an enduring meaning. It is a part of the human being and our thoughts and feelings about our identity. Such a choice may be why questions about the most appropriate regulation of the crime under consideration have a special place in the public discourse.
Design of Virtual Reality Based Game for Dual Enhancement of City Monuments and Brand Image
Authors: Aydi Yassine , Elleuch Meriam 
Published: March 2024

The increasing accessibility of Virtual reality (VR) technology presents an opportunity for enhancing human immersion in several domains (Industrial, Social, Media, Cultural heritage, etc.). Moreover, it has huge impact to leverage its interaction and engagement; to un-dominate person on live, work, and diversion. The development of innovative VR-driven method is a sign of evolvement witnessed by the interaction design industry. In this respect, the work presents a complete framework for the design of virtual reality-based game; offering features, mechanisms, and 3D models that facilitate the development of interactive scenes, which reveal of the city’s historic monuments reality. The main research question focuses on empirically establishing the impact of virtual reality on video game design, including its influence on in-game cultural placement and its potential to enhance the retention of legacy game experiences within players’ memories. The results show that the game experience is felt original, enjoyable, and appealing for the user’s target group. Also, participants appreciate the use of VR technologies to explore cultural scenes and product; and to enhance empathy within a virtual experience. Furthermore, our research extends recent studies, proposing a VR-based design methodology, as well as, an assessing process. It guides the creation of visual representation of monuments, artifacts, and culture. Moreover, it improves user’s point of view and knowledge of the place they visit, within playing the WallysCar Crash Team Racing (WCTR) game. Our project intended to achieve a twofold purpose related to the Tunisian context: discovering the popular “Sfax City” with historical and patrimonial monumental heritage, while promoting the local industry creation.
Politik Identitas dalam Kampanye Politik Ganjar Pranowo Menjelang Pilpres 2024
Authors: Rosdiana Anggita Cahya , Annis Azhar Suryaningtyas  
Published: March 2024

Politik identitas mengacu pada strategi politik yang berfokus pada identitas kelompok tertentu seperti ras, agama, etnis, gender, orientasi seksual, atau karaketristik lainnya. Dalam konteks pemilihan presiden melibatkan strategi politik yang mencoba menggerakan dan memobilisasi dukungan dari berbagai kelompok identitas. Pemilihan presiden 2024 di Indonesia menjadi fokus perhatian publik nasional. Namun, problem yang terjadi menjelang pilpres yakni adanya politik identitas dalam kampanye yang dilakukan oleh salah satu calon presiden yakni Ganjar Pranowo. Penelitian ini bertujuan menganalisis politik identitas menggunakan teori politik identitas Castells dalam kampanye politik yang dilakukan Ganjar Pranowo. Penelitian ini menggunakan metode penelitian deskriptif kualitatif, penelitian dilakukan dengan analisis konten yakni mengamati dan memahami beberapa politik identitas yang dilakukan Ganjar di media sosial. Hasil penelitian menunjukkan Ganjar Pranowo memanfaatkan berbagai strategi politik identitas dengan tujuan membangun citra positif, Ganjar berupaya melegitimasi identitas sebagai tokoh yang religius dengan muncul dalam tayangan adzan, keikutsertaannya di acara hiburan MasterChef Indonesia menimbulkan pertanyaan dibalik motif keikutsertaannya, sehingga dianggap sebagai kampanye politik yang menunjukkan elemen resistensi identitas, proyek identitas dilakukan Ganjar melalui berbagai postingan di media sosial, termasuk momen sholat dan kunjungan ke pesantren, bertujuan untuk menciptakan citra politik sebagai tokoh agama yang kuat, serta mendapatkan dukungan dari kelompok agama.
Practical Manual of Inorganic, Organic and Medicinal Chemistry
Authors: Nagar Dr. Akhil , Lokwani Dr. Deepak , Bendale Dr. Atul , Chaudhari Mr. Pritam B. 
Published: March 2024

This is regarding publishing the practical book for pharmaceutical syllabus as per PCI. Here we have included All Practicals of Inorganic, Organic and Medicinal Chemistry (from Sem-1 to Sem-6). Although there are many books which are published in this manner for individual subject but very few which include all the practicals of chemistry. The books which are available, practically they are not feasible to perform in laboratory.

The practical procedure included here are:
1. Performed already in lab.
2. Procedures are designed taking reference of PATENTS and BASIC METHODS.
3. The melting points are mentioned for individual intermediates also.
4. Whenever required, additional procedures for the synthesis of also mentioned.
5. More easy and feasible separation methods are mentioned.
6. Reaction and their importance are explained for the procedure during separation.