bluuebunny/crossref_metadata_2025_split huggingface dataset:
AKTIVITAS ANTIOKSIDAN EKSTRAK RIMPANG JAHE MERAH (Zingiber officinale var. Rubrum) DENGAN VARIASI KONSENTRASI ETANOL, DAN AKTIVITAS FAGOSITOSIS
Authors: Setyawati Herni , Raras Anindita Puspita , Amrullah Adinugraha , Herliana Faticha , Ade Nanda Sukma 
Published: March 2024

Antioksidan alami memberikan banyak manfaat farmakologi. Jahe merupakan tanaman yang mempunyai aktivitas biologis termasuk antioksidan. Tujuan dalam penelitian ini yaitu mengetahui aktivitas antioksidan dan aktivitas fagositosis ekstrak jahe merah. Serbuk jahe merah diekstraksi menggunakan etanol dengan konsentrasi 70%, 80%, dan 96%. Metode ekstraksi menggunakan maserasi dan maserasi dengan ultrasonikasi. Ekstrak dengan aktivitas antioksidan tertingi akan diuji aktivitas fagositosisnya. Analisis kualitatif dilakukan dengan menggunakan kromatografi lapis tipis. Uji aktivitas antioksidan menggunakan metode 1,1-diphenyl-2-picrylhydrazyl (DPPH) dan alat Spektrofotometer UV-Vis. Ekstrak dengan aktivitas antioksi tertinggi dilakukan uji aktivitas fagositosis. Nilai IC50 vitamin C sebagai pembanding ialah 2,08 ppm. Nilai IC50 maserasi ekstrak jahe merah menggunakan etanol 70%, 80%, 96% ialah 92,38%, 81,11 dan 86,58 ppm, sedang pada maserasi ultrasonikasi ialah 90,14ppm, 72,86ppm,85,81ppm. Uji fagositosis ektrak etanol 80% pada konsentrasi 5ppm, 25ppm, 125ppm dan 625ppm memberikan rerata presentase aktivitas fagositosis sebesar 7,19; 5,70; 32,04; 33,50. Kesimpulan yang didapat ekstrak etanol jahe merah konsentrasi 70%, 80%, 96% dengan metode maserasi maupun ultrasonikasi memiliki aktivitas antioksidan yang tergolong kuat. Pada konsentrasi 625ppm ekstrak etanol 80% dengan kandungan senyawa kimia golongan alkaloid, flavanoid dan saponin memiliki potensi aktivitas fagositosis jika dibanding kontrol normal.
Performance Classification for Lasso Weights with Penalized Logistic Regression for High-Dimensional Data
Authors: Raheem khudhair Afiaa , Mohammed. Hussein Saja 
Published: March 2024

في البيانات ذات الأبعاد العالية هناك مشكلة عدم معرفة اختيار المتغيرات ذات الاهمية لذلك يعد أداء التصنيف معياراً مهماً لمعرفة اهم المتغيرات الداخلة في النموذج حيث يلخص هذا البحث اداء تصنيف متغير الاستجابة للبيانات عالية الابعاد من خلال تطبيق اوزان مختلفة للاسو مع الوزن المقترح من قبل الباحث مع انموذج الانحدار اللوجستي الجزائي وتم تطبيق هذه الازوان على بيانات حقيقية تضمنت 12600 جين لعينة مؤلفة من 100 مشاهدة وعينة صغيرة تم جمعها من قبل الباحثة حيث تضمنت 40 انثى مصنفة )27 مصابة و13 غير مصابة (وتم استخدام برنامج R للحصول على النتائج حيث تم التوصل الى ان الاوزان تعمل بدقة عالية وجيدة لغرض التصنيف وحققت الطريقة المقترحة نتائج جيدة وعملية في اختيار افضل المتغيرات التوضيحية لتصنيف متغير الاستجابة .

نوع البحث: مستل من اطروحة دكتوراه .
Perancangan Media Informasi Mengenai Rahmah El-Yunusiyyah Dalam Memperjuangkan Pendidikan Perempuan Melalui Motion Graphic
Authors: Husna Assaidatul , Zakki Ahmad 
Published: March 2024

Rahmah El-Yunusiyyah merupakan tokoh perempuan Minangkabau yang ikut terlibat dalam arus “pembaharuan” modernisasi di bidang pendidikan. Bermula dari keprihatinannya terhadap nasib perempuan di jamannya, Rahmah El-Yunusiyyah berupaya memperbaiki kondisi kaumnya melalui bidang pendidikan dengan mendirikan Diniyyah Puteri. Perancangan ini menyajikan cerita perjuangan Rahmah El-Yunusiyyah dalam memperjuangkan pendidikan perempuan Indonesia ke dalam visual dengan target audience yaitu remaja dewasa berusia 12-18 tahun. Perancangan dilakukan dengan menggunakan metode Design Thinking. Metode ini menggunakan emphatize (proses dalam mengamati, mengetahui, memahami, merasakan, dan kepekaan terhadap lingkungan target audience), define (brainstorming, analisis), ideate (konsep dan strategi), dan prototype (pengerjaan karya). Dengan adanya media informasi mengenai perjuangan Rahmah El-Yunusiyyah ini diharapkan media informasi dapat mengenalkan tokoh. Hal ini dipupuk dengan menanamkan kebanggaan terhadap tokoh kenamaan asal Minangkabau tersebut melalui media sosial dengan menggunakan teknik motion graphic dan teknik visual storytelling.
PENGETAHUAN CEDERA OLAHRAGA PADA MAHASISWA FAKULTAS ILMU KESEHATAN UNIVERSITAS MUHAMMADIYAH PEKAJANGAN PEKALONGAN
Authors: Dias Arif Budiani Dias arif budiani 
Published: March 2024

Setiap pelaku olahraga memiliki resiko mengalami cedera saat melakukan aktivitas fisik seperti pada pendidikan jasmani, olahraga prestasi maupun olahraga kebugaran. Setiap lulusan dan mahasiswa UMPP diharapkan memiliki kemampuan untuk dapat mencegah dan menangani cedera yang terjadi. Tujuan dalam penelitian ini adalah untuk mengetahui tingkat pengetahuan cedera olahraga mahasiswa UMPP yang terkait dengan macam-macam cedera olahraga, lokasi cedera, faktor-faktor penyebab terjadinya cedera olahraga, penanganan pada cedera olahraga dan upaya pencegahan terjadinya cedera olahraga. Metode penelitian menggunakan teknik survey dengan menyebarkan angket dan wawancara yang diberikan kepada mahasiswa UMPP. Populasi dan sampel penelitian ini adalah mahasiswa UMPP semester IV tahun ajaran 2015/2016, pengambilan sampel menggunakan random sampling.
Hasil dari penelitian ini adalah tingkat pengetahuan cedera olahraga mahasiswa Semester 2 26% katagori tinggi sekali, 72% katagori tinggi dan 2% katagori sedang. Tingkat pengetahuan cedera mahasiswa semester 6 4% katagori tinggi sekali,86% katagori tinggi, dan 10% katagori sedang; Tingkat pengetahuan mahasiswa semester 4 92% katagori tinggi dan 8% katagori sedang. Mahasiswa UMPP belum dapat mengimplementasikan penanganan cedera olahraga. Kesimpulan dari penelitian ini adalah tingkat pengetahuan cedera olahraga mahasiswa UMPP dalam katagori tinggi
GAMBARAN DAN KONSEP TENTANG PERANAN VITAMIN
Authors: Farida Daffa akhdani nadhif 
Published: March 2024

Vitamin adalah bagian yang penting dari makanan sehat. Bila seseorang mengkonsumsi berbagai variasi makanan, maka kemungkinan untuk mengalami kekurangan vitamin adalah sangat kecil. Orang-orang yang menjalani diet ketat mungkin tidak mendapatkan cukup vitamin atau mineral tertentu. Contohnya seorang vegetarian yang sangat ketat bisa mengalami kekurangan vitamin B12, yang hanya bisa diperoleh dari makanan yang berasal dari hewan. Sebaliknya, mengkonsumsi sejumlah besar vitamin dan mineral tambahan tanpa pengawasan medis, dapat menimbulkan efek yang berbahaya.
Pentingnya vitamin dalam menjaga kesehatan manusia telah mendapatkan perhatian luas dari berbagai kalangan, termasuk para ilmuwan, peneliti, praktisi medis, dan masyarakat umum. Kekurangan vitamin atau defisiensi vitamin dapat menyebabkan berbagai gangguan kesehatan, seperti berkurangnya sistem kekebalan tubuh, gangguan pertumbuhan dan perkembangan, masalah kulit, anemia, dan masalah kesehatan lainnya.
Analisis Kritis Pasal 156 (C) KHI Mengenai Pemindahan Hak Asuh Anak dalam Konteks Penelantaran oleh Ibu: Perspektif Maqāshid Al-Syarī’ah
Authors: Kurniawan Mitra , Zulfahmi Bustami  , Sofia Hardani  
Published: March 2024

Purpose – This study aimed to perform a critical analysis of Article 156 (c) of the Indonesian Compilation of Islamic Law (KHI), which exhibited a legal loophole. The article failed to clearly and unequivocally address the situation where the mother might be capable of caring for the child but the father, despite having the means, refused to provide support. Consequently, in cases where the mother lacked sufficient income, the child could be left abandoned.
Methods – This research falls under the category of literature review within the field of Islamic studies, employing a qualitative normative approach. The methodology utilized for data processing and drawing conclusions was content analysis.
Findings – The findings of the study underscored the necessity of examining the aforementioned issues through the lens of maqāshid al-syarī'ah, as they are intricately linked to the question of whether the mother's custody should be upheld or if it is more beneficial to transfer it to the party with similar custodial rights. This perspective is crucial as it considers the overarching objectives and principles of Islamic law, guiding the decision-making process towards outcomes that align with the broader aims of justice, welfare, and protection of the child's best interests.
Research implications –The theoretical implications encompass the potential expansion of concepts and legal thoughts in Islamic law concerning the protection of children's rights, and provide a foundation for critical reflection on existing legal frameworks. Thus, the research findings may aid in the development of a more inclusive theory of Islamic law that aligns with principles of humanity and justice.
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Originality/value – This study addresses a notable gap in Indonesian Islamic law concerning child custody rights, specifically regarding maternal abandonment. By critically analyzing Article 156 (c) of the Indonesian Compilation of Islamic Law (KHI), the research identifies a legal loophole affecting children's welfare when mothers lack sufficient support. Unlike previous studies, this research integrates maqāshid al-syarī’ah principles, offering a comprehensive perspective.
تطبيق نموذج التعليم بالإكتشاف في تعليم اللغة العربية لترقية إستعاب المفردات لتلاميذ الصف الثامن بمدرسة الباركة المتوسطة الإسلامية بورواكارتا
Authors: Maisarah Azzahra Nissa , Taufik Luthfi  , Fajar Ahmad , Rizal Munir Dede 
Published: March 2024

مستخلص
تعلم اللغة العربية بمدرسة الباركة المتوسطة الإسلامية بورواكارتا يظهر عملية ليست مثالية. بشكل عام، لا تزال عملية التعلم المستخدمة تقليدية. ومع ذلك، لا يزال المعلم يبذل جهدًا لتصميم وإنشاء أحدث نموذج تعليمي، أي باستخدام التعلم بالإكتشاف. تهدف هذا البحث إلى إلقاء نظرة على فعالية نموذج التعلم بالإكتشاف في تعلم اللغة العربية لتلاميذ الصف الثامن بمدرسة الباركة المتوسطة الإسلامية بورواكارتا. والأهداف لهذا البحث كما تلي : 1). معرفة تطبيق نموذج التعليم بالإكتشاف المفردات لتلاميذ الصف الثامن بمدرسة الباركة المتوسطة الإسلامية بورواكارتا، 2). معرفة ترقية إستعاب المفردات لتلاميذ الصف الثامن بمدرسة الباركة المتوسطة الإسلامية بورواكارتا، 3). معرفة تطبيق نموذج التعليم بالإكتشاف لترقية إستعاب المفردات لتلاميذ الصف الثامن بمدرسة الباركة المتوسطة الإسلامية بورواكارتا. نوع البحث المستخدم هو البحث الكمي مع نوع بحث دراسة الحالة. تقنيات البيانات المستخدمة هي المراقبة والاستبيان والاختبار. تشير نتائج هذه البحث إلى وجود تأثير لتعلم مفردات اللغة العربية باستخدام نموذج التعلم بالإكتشاف لترقية إستعاب المفردات لدى لتلاميذ الصف الثامن بمدرسة الباركة المتوسطة الإسلامية بورواكارتا، معادلة الانحدار في هذه البحث هي 0.002، ويمكن استنتاج أن المفردات التعلم باستخدام نموذج التعلم بالإكتشاف لترقية إستعاب المفردات لدى التلاميذ له تأثير كبير.
الكلمات الرئيسية: تعلم اللغة العربية ؛ المفردات ؛ نموذج التعلم بالإكتشاف
Halogenated dicyanobenzene-based photosensitizer (3DPAFIPN) as a thermally activated delayed fluorescence (TADF) used in gram-scale photosynthesis 3,4-dihydropyrimidin-2-(1H)-one/thione derivatives via a consecutive visible-light-induced electron-transfer pathway
Authors: Mohamadpour Farzaneh , Amani Ali Mohammad 
Published: March 2024

Background: Organic dyes often have shorter lifetimes in the excited state, which is a major obstacle to the development of effective photoredox methods. The scientific community has shown a great deal of interest in a certain class of organic chromophores because of their unique characteristics and effectiveness. One characteristic of the molecules under research is thermally activated delayed fluorescence (TADF), which is only observed in molecules with a tiny energy gap (often less than 0.2 eV) between their lowest two excited states, i.e., singlet excited state (S1) and triplet excited state (T1). The extended singlet excited states arising from TADF and the simplicity with which their redox potentials may be altered make the isophthalonitrile family of chromophores an attractive option for organic photocatalyst applications.Methods: The Biginelli reaction between β-ketoesters, arylaldehydes, and urea/thiourea has been used to build a sustainable technique for the production of 3,4-dihydropyrimidin-2-(1H)-one/thione derivatives. In the present study, the development of a green radical synthesis approach for this class of compounds is addressed in depth. As a photocatalyst, a new halogenated dicyanobenzene-based photosensitizer was employed in this study. As a renewable energy source activated by a blue LED, it was dissolved in ethanol, at room temperature in air atmosphere. The primary objective of this research is to employ a novel donor-acceptor (D-A) based on halogenated cyanoarene that is affordable, easily available, and innovative.Findings: The 3DPAFIPN [2,4,6-tris(diphenylamino)-5-fluoroisophthalonitrile] photocatalyst, a thermally activated delayed fluorescence (TADF), induces single-electron transfer (SET) in response to visible light, offering a straightforward, eco-friendly, and highly efficient process. Additionally, we determined the 3,4-dihydropyrimidin-2-(1H)-one/thione derivatives turnover frequency (TOF) and turnover number (TON). It has also been demonstrated that gram-scale cyclization is a workable method for industrial purposes.
Clinical study of reoperation for acute type A aortic dissection
Authors: Feng Yi , Ma Xian-Tao , Zhang Xiao-Xue , Wajeehullahi Akilu , Chen Zi-Jun , Li Shi-Liang , Cheng Cai 
Published: March 2024

ObjectiveThe initial operation for type A aortic dissection has limitations, and there may be a need for reoperation in cases such as giant pseudoaneurysm formation and reduced blood supply to the distal vessels. In this study, we collected case data of patients who underwent cardiac major vascular surgery at our hospital to analyze the effectiveness of reoperation treatment options for type A aortic dissection and to summarize our treatment experience.MethodBetween June 2018 and December 2022, 62 patients with type A aortic dissection (TAAD) underwent reoperation after previous surgical treatment. Of these, 49 patients (45 males) underwent endovascular aortic repair (EVAR) with a mean age of (49.69 ± 10.21) years (30–75 years), and 13 patients (11 males) underwent thoracoabdominal aortic replacement (TAAR) with a mean age of (41.00 ± 11.18) years (23–66 years). In this study, we retrospectively analyzed the recorded data of 62 patients. In addition, we summarized and analyzed their Computed Tomographic Angiography (CTA) results and perioperative complications.OutcomeIn the EVAR group, 47 patients (95.92%) were successfully implanted with overlapping stents, and 2 patients died in the perioperative period. Postoperative complications included cerebral infarction (4.08%), acute renal insufficiency (30.61%), pulmonary insufficiency and need for ventilator (6.12%), poor wound healing (2.04%), postoperative reoperation (16.33%), and lower limb ischemia (2.04%). In the TAAR group, 12 patients (92.31%) were successfully revascularized and 1 patient died in the perioperative period. Postoperative complications included cerebral infarction (7.69%), acute kidney injury (46.15%), pulmonary insufficiency and need for ventilator (15.38%), poor wound healing (30.77%) and postoperative reoperation (15.38%).ConclusionAccording to the results of the study, compared with TAAR, EVAR was less invasive, faster recovery, and offered a better choice for some high-risk and high-age patients with comorbid underlying diseases. However, the rate of revascularization was higher after EVAR than TAAR due to vascular lesions. Compared with the use of ascending aortic replacement + hemi-aortic arch replacement for acute type A aortic dissection in many countries and regions, the use of ascending aortic replacement + aortic arch replacement + elephant trunk stent is more traumatic in China, but facilitates reoperation. For young patients, the choice of treatment should be individualized combining vascular lesions and long-term quality of life.
To diagnose primary and secondary squamous cell carcinoma of the thyroid with ultrasound malignancy risk stratification
Authors: Zhang Xiumei , Wei Boxiong , Nong Lin , Zhang Hong , Zhang Jixin , Ye Jingming 
Published: March 2024

ObjectivesThis study aimed to investigate the clinico-ultrasound features of primary squamous cell carcinoma of the thyroid (PSCCT) and secondary SCCT (SSCCT) and evaluate the accuracy of fine needle aspiration (FNA) recommendation for SCCT with American College of Radiology-Thyroid Imaging and Reporting Data System (ACR-TIRADS) and Chinese-TIRADS (C-TIRADS).Materials and methodsWe retrieved 26 SCCT patients (11 PSCCT, 15 SSCCT) from our hospital’s pathology database (5,718 patients with thyroid malignancy) over 23 years. Medical records and ultrasound data of the 26 patients with 27 SCCTs were analyzed retrospectively, and each SCCT focus was categorized based on the two TIRADSs.ResultsFor 26 patients (21 males, 5 females) with an age range of 42-81 years, rapidly enlarging thyroid/neck nodules (18/26, 69.2%), dysphagia (7/26, 26.9%), hoarseness (6/26, 23.1%), dyspnea (5/26, 19.6%), cough (4/26, 15.4%), neck pain (2/26, 7.7%), B symptoms (2/26, 7.7%), and blood in sputum (1/26, 3.8%) were presented at diagnosis. Five asymptomatic patients (5/26, 19.2%) were detected by ultrasound. Hoarseness was more common in PSCCT (5/11, 45.5%) than in SSCCT (1/15, 6.7%) (P=0.032). For 27 SCCTs with a mean size of 3.7 ± 1.3 cm, the ultrasound features consisted of solid (25/27, 92.6%) or almost completely solid composition (2/27, 7.4%), hypoechoic (17/27, 63%) and very hypoechoic echogenicity (10/27, 37%), irregular/lobulated margin with extra-thyroidal extension (27/27, 100%), taller-than-wide shape (13/27, 48.1%), punctate echogenic foci (6/27, 22.2%), hypervascularity (23/27, 85.2%) and involved neck lymph (13/26, 50.0%). A total of 27 SCCTs were evaluated as high malignancy risk stratification (≥TR4 and 4B) by the two TIRADSs and recommended FNA in 96.3–100% (26/27, 27/27). Pathologically, more than half of PSCCTs (7/12, 58.3%) and a quarter of SSCCTs (4/15, 26.7%) were poorly differentiated, while moderately and well-differentiated grades were observed in 5 PSCCTs and 11 SSCCTs (P=0.007). Thirteen patients (50.0%) underwent surgery with radical operation in 5 cases (5/13, 38.5%).ConclusionSCCT is an extremely rare and aggressive malignancy with a male predominance. PSCCT and SSCCT had similar clinical and ultrasound features except for tumor differentiation and the symptom of hoarseness. SCCT showed a high malignancy risk stratification in ACR-TIRADS and C-TIRADS, with a high rate of FNA recommendation.
Regional disparities, dynamic evolution, and spatial spillover effects of urban-rural carbon emission inequality in China
Authors: Wei Jiangying , Hu Ridong , Li Yanhua , Shen Yang 
Published: March 2024

ObjectiveThis study recalculates the carbon emissions of urban and rural residents in China, analyzing the dynamic evolution trends of urban and rural carbon emissions. It explores the spatial spillover effects centered around the inequality in carbon emissions between urban and rural areas.MethodsThe study calculates the carbon emissions of urban and rural residents in each province based on the IPCC method. Non-parametric kernel density estimation is employed to depict the dynamic evolution characteristics of national, urban, and rural carbon emissions. The Theil Index is used to measure the disparities in urban and rural carbon emissions in major strategic regions, further applying the Theil Index to evaluate the inequality of urban and rural carbon emissions across provinces. This helps identify the driving factors affecting the inequality of urban and rural carbon emissions and their spatio-temporal effects.FindingCarbon emissions from urban and rural residents in China present a divergent development pattern. Urban emissions have increased, with inter-provincial disparities widening; rural emissions tend to stabilize, with slight growth in inter-provincial gaps. The overall inequality of carbon emissions in various regions of China experiences a three-phase journey of rise, decline, and stabilization. Urban inequality first increases then decreases, while rural inequality gradually lessens, showing clear regional and urban-rural differences. Market and government factors significantly impact the inequality of urban and rural carbon emissions. The development of the digital economy aids in reducing inequality and generates significant spatial spillover effects. The relationship between economic development level and carbon emission inequality is U-shaped. Industrial structure optimization can reduce urban-rural inequality, but its spatial spillover effect is not significant. Government intervention has limited effects, while environmental regulations may increase inequality. Opening up to the outside world helps reduce inequality, and the impact of population density is complex.
Neurovascular coupling is altered in women who have a history of brain injury from intimate partner violence: a preliminary study
Authors: Wallace Colin , Smirl Jonathan D. , Adhikari Shambhu P. , Jones K. Elisabeth , Rieger Matt , Rothlander Krystal , van Donkelaar Paul 
Published: March 2024

IntroductionIntimate partner violence (IPV) is a global health crisis with 30% of women over the age of 15 experiencing at least one event in their lifetime. Brain injury (BI) due to head impacts and/or strangulation is a common but understudied part of this experience. Previous research has shown BI from other injury mechanisms can disrupt neurovascular coupling (NVC). To gain further insight into whether similar changes occur in this population, we assessed NVC responses in women with a history of IPV-BI.MethodsNVC responses were measured for the middle and posterior cerebral arteries (MCA, PCA) using transcranial Doppler ultrasound while participants performed a complex visual search task. The lifetime history of previous exposure to IPV-BI was captured using the Brain Injury Severity Assessment (BISA) along with measures of post-traumatic stress disorder (PTSD), anxiety, depression, substance use, and demographic information. Initial analyses of NVC metrics were completed comparing participants who scored low vs. high on the BISA or did or did not experience non-fatal strangulation followed by a stepwise multiple regression to examine the impact of PTSD, anxiety, and depression on the relationship between the NVC metrics and IPV-BI.ResultsBaseline and peak cerebral blood velocity were higher and the percentage increase was lower in the PCA in the low compared to the high BISA group whereas no differences between the groups were apparent in the MCA. In addition, those participants who had been strangled had a lower initial slope and area under the curve in the PCA than those who had not experienced strangulation. Finally, the stepwise multiple regression demonstrated the percentage increase in the PCA was significantly related to the BISA score and both depression and anxiety significantly contributed to different components of the NVC response.ConclusionsThis preliminary study demonstrated that a lifetime history of IPV-BI leads to subtle but significant disruptions to NVC responses which are modulated by comorbid depression and anxiety. Future studies should examine cerebrovascular function at the acute and subacute stages after IPV episodes to shed additional light on this experience and its outcomes.