bluuebunny/crossref_metadata_2025_split huggingface dataset:
Functional Seizures and Chronic Pain: A Narrative Review of common Pathomechanisms and Clinical Implications
Authors: Kannan Siddarth , Patel Kajal , Basilio Daniela Di , Kirkby Antonia , Sivan Manoj , Jones Anthony , Mohanraj Rajiv , Das Abhijit 
Published: March 2024

Abstract
Background
Functional seizures (FS) manifest as episodic events, bearing superficial similarities to epileptic seizures and represent a major component of Functional Neurological Disorder (FND). FS frequently present with the co-morbidity of chronic pain and the pronounced clinical and epidemiological associations between these conditions suggest potential shared pathomechanisms. Although conventional neuroimaging and neurophysiological assessments do not detect abnormalities in either condition, advanced biophysical signal analyses offer potential biomarkers.
Method
We undertook comprehensive literature review encompassing studies employing EEG, MEG, functional MRI, PET, and SPECT in FS and chronic pain. Due to the heterogenous nature of the collected data, the results of data extraction and analysis are presented in the form of a narrative synthesis.
Results
Despite some limitations, altered neural network dynamics are evident in both FS and chronic pain, revealing intriguing common mechanisms. Both conditions exhibit overactivation in sensorimotor networks and alterations in the Default Mode Network (DMN), impacting self-awareness and pain perception. Emotional processing regions, like the anterior cingulate cortex and insula, were affected in both conditions. Furthermore, Thalamocortical dysrhythmia(TCD) offers an intriguing link, influencing pain perception and seizure-like activities. Finally, suppressed alpha oscillations, linked to sensory perception, are prevalent in both conditions.
Conclusion
We identified shared neural mechanisms and a possible novel explanation (TCD) for co-occurrence of FS and chronic pain. These necessitate further exploration in subsequent studies incorporating patients exhibiting both disorders concurrently. Such research direction holds the potential to introduce novel therapies for not only managing FS or chronic pain, but also managing FND.
Advancing Image Encryption with a Novel One-Dimensional Chaotic Map
Authors: Li Yuxuan 
Published: March 2024

Abstract
The secure transmission of images is a critical aspect of information security, especially in an era where digital communication is ubiquitous. Image encryption, leveraging the complexity and unpredictability of chaotic dynamical systems, offers a robust means to safeguard image data against unauthorized access. In this study, we introduce a novel one-dimensional chaotic map, referred to as 1D-SCPCM, and conduct extensive experiments to validate its exceptional chaotic properties. Unlike traditional one-dimensional chaotic maps, 1D-SCPCM exhibits enhanced stability and consistency in its chaotic dynamics across various control parameters, making it highly suitable for image encryption tasks. Utilizing the capabilities of 1D-SCPCM, we develop an advanced image encryption scheme to effectively secure digital images. Our findings underscore the potential of 1D-SCPCM as an effective tool for achieving high levels of security in image encryption and as a steppingstone towards more secure and reliable methods of protecting digital information. This research makes a significant contribution to the fields of chaos theory by presenting a novel approach that combines theoretical innovation with practical security solutions, marking a significant advancement in safeguarding sensitive visual data.
GC-MS Analysis of Hexane Extract of Artabotrys
Authors: Kori Pramila , Mehta B. K. 
Published: March 2024

Abstract
Hexane eluate was extracted from the leaves of Artabotrys Odoratissimus (R.Br.). GC-MS analysis revealed the presence of twenty our peaks conforming to twenty-four compounds, out of these twenty compounds were recognized by comparing their retention time and the interpretation of their mass spectra. These compounds are Eicosane, Heneicosane, 1-Methyl Nonadecane, Heptadecane, Dibutylphthslate,3-Methylheneicosane, Eicosane-3-Ene, 2-Methyl eicosane, Docosane, 10-Methyl Hen eicosane, Nonadecane, Tetracosane, Tetratriacontane, Hexadecenoic Acid, Octadecanoic Acid, Bis (2-Ethyl, Hexyl) Phthalate, 1-Docosene, 2-Dodecanone, 1-Nonadecanol, 2,7,10-Trimethyldodecane. The quantitative estimations of each peak were made by estimating area of the peak by a computer, connected with GC-MS instrument
Rekreációs jelleggel úszó edzésre járó 11-17 éves gyermekek gerincének állapota
Authors: Nagyváradi Katalin , Arany Dániel , Szigethy Mónika , Bíróné Ilics Katalin 
Published: March 2024

A „legegészségesebb” sportágként számon tartott úszás során a szárazföldi mozgásvégrehajtások közben tapasztalható törvényszerűségek nem érvényesülnek. Nincsenek hirtelen nagy erőbehatások, ütődések, emiatt az ízületek jelentősen kisebb terhelésnek vannak kitéve. Ez a közeg kulcsszerepet játszik a gyermekkorban jelentkező mozgásszervi elváltozások prevenciójában és esetleges rehabilitációjában is. Kutatásunk célja volt felmérni különböző korosztályokban rendszeresen – rekreációs céllal - úszóedzésre járó gyermekek gerincének fiziológiás állapotát gerincegér (Spinal Mouse) használatával. Vizsgálatunkba két egyesület úszóit vontuk be. Az eredményeink azt mutatják, hogy mintánkban - rendszeres úszás ellenére is - fellelhetők, főként a háti gerinc szakasz középső szegmenseiben, valamint a teljes ágyéki gerincszakaszon gerincmobilitásbéli problémák, a háti gerincszakasz felső szegmensében, valamint a háti gerincszakasz alsó-ágyéki gerincszakasz felső szegmensében mérsékelt tartásbéli gyengeségek. Az eredmények ismeretében nagyobb hangsúlyt kellene fektetni a szárazföldi edzések során a tehermentesített helyzetben történő felületes és mélyhátizomzat erősítésére. Valamint célszerű lenne az úszóedzések kiegészítéseként rendszeresen beiktatni szárazföldi mobilizáló és nyújtó gyakorlatokat.
Preparation, Characterization, and Hepatoprotective Activity Evaluation
of Quercetin-loaded Pluronic® F127/Chitosan-Myristic Acid Mixed Micelles
Authors: Telange Darshan R. , Kamdi Seema , Hemke Atul T. , Pethe Anil M. , Lambole Vijay B. , Telrandhe Umesh B. 
Published: March 2024

Background::
Quercetin (QTN) is a flavonol antioxidant found in foods, medicinal
plants, fruits, vegetables, and beverages. QTN oral consumption produces several biological effects,
including antioxidant, cardioprotective, anti-apoptotic, anti-cancer, neuroprotection, anti-hypertensive,
and chemo preventive.

Objective::
The study aimed to prepare Pluronic®F127/chitosan-myristic acid copolymer
(PF127/C-MAc)-based mixed micelles (QTN MM) to improve the biopharmaceutical and hepatoprotective
potential of QTN.

Methods::
QTN MM was developed employing thin-film hydration and optimized using full factorial
design (FFD). Optimized QTN MM was analyzed using scanning electron microscopy (SEM),
differential scanning calorimetry (DSC), Fourier-transform infrared spectroscopy (FT-IR), powder
x-ray diffractometry (PXRD), in vitro dissolution, ex vivo permeation, and in vivo antioxidant activity
in carbon tetrachloride (CCL4)-induced albino rats.

Results::
PF127/C-MAc ratio (1:1) with CMC value ~ 5 μg/mL showed the suitability for MM.
Characterization supported the formation of MM. QTN MM revealed prominent encapsulation efficiency
and drug loading of about ~ 95.10% and ~ 12.28% w/w, respectively. MM spherical
shape of QTN with a smaller particle size of ~ 34.08 nm and a higher zeta potential of ~ 36.24 nm
indicated excellent physical stability. Dissolution and ex vivo permeation results revealed higher
dissolution and permeation of QTN MM compared to QTN and PM. In vivo antioxidant activity
suggested that QTN MM at (~ 20 mg/kg, p.o.) restored the enhanced marker enzyme level compared
to QTN.

Conclusion::
The findings demonstrate that developed QTN MM could be used as an alternative
nanocarrier to increase the biopharmaceutical and hepatoprotective potential of QTN and other
flavonoids.
A Snapshot of Biomarkers in Psoriasis
Authors: Abhale Krushna , Veeranjaneyulu Addepalli , Desai Shivani 
Published: March 2024

:
A persistent long-standing, inflammatory skin condition that is brought on by a variety
of factors is psoriasis. It is distinguished by itchy, scaly, reddish plaques, particularly on areas of
the body that are frequently chafed, including the extensor sites of the limbs. Recent developments
in molecular-targeted therapy that use biologics or small-molecule inhibitors can effectively
cure even the worst psoriatic indications. The outstanding clinical outcomes of treatment help to
clarify the disease's detrimental consequences on quality of life. Biomarkers that identify deep remission
are essential for developing uniform treatment plans. Blood protein markers such as
AMPs that are consistently quantifiable can be very helpful in routine clinical practice. The
metabolic pathways involve biomarkers that can not only help diagnose psoriasis in a clinical setting
but also indicate its severity based on the levels present in the body. Machine learning and AI
have made a diagnosis of the expression of genes as biomarkers more accessible. In this article,
biomarkers, as well as their key role in psoriasis, are discussed
The Neurochemical Anatomy of Runway Acquisition and Extinction
Authors: Lalonde Robert , Strazielle Catherine 
Published: March 2024

Abstract:
A review is presented as to the neurochemical basis of the straight runway task, usually
consisting of an acquisition phase followed by an extinction phase. During the acquisition of the
appetitive runway task, running speeds from the start box to the goal box progressively increase
over trials and then decrease when the reward is withheld. Runway extinction is susceptible to lesions of the limbic system, including the medial frontal cortex, the hippocampus, the septum, the
amygdala, and the dorsomedial thalamus. When specific neurotransmitter systems are examined,
extinction was delayed when noradrenaline transmission was impeded, perhaps involving noradrenergic projections to the hippocampus and neocortex. Extinction was likewise delayed after either
facilitation or blocking of dopamine transmission, a result implicating an inverted U-shaped function caused by dopamine’s role in behavioral activation or reward processes. Extinction was also
delayed by indirect GABAA receptor agonists injected during acquisition, explained by druginduced disinhibitory tendencies. This simple paradigm may provide information about the effects
of a physiological manipulation on both cognition and emotion.
Barriers to Health Self-Management Among Older People with Hypertension and Diabetes in Institutions in China: A Phenomenological Study
Authors: Liu Rong , Dahlan Akehsan , Mohd Fahmi Teng Nur Islami , Zhan Xingxin Zhan 
Published: March 2024

The objective of this qualitative study is to explore the barriers to self-management among older people with hypertension and diabetes in institutional settings from the perspectives of both patients and health professionals in China. A qualitative phenomenological study used semi-structured face-to-face interviews involving eight older persons and ten health professionals. Thematic analysis revealed two main themes: 1) individual-related factors and 2) limited social support. Tailored interventions considering these multifaceted barriers can positively impact the quality of life and health outcomes for older individuals dealing with hypertension and diabetes in institutional settings.
Effect of the Occupational Engagement Home Program (MyHOeME©) for Older Persons in the Community
Authors: Dahlan Akehsan , Haidhir Harnisha , Tengku Makhtar Tengku Mohd Asri , Sahid Muhammad Hidayat 
Published: March 2024

Malaysia faces a pressing issue as its older population is projected to reach 16% by 2030. While global and national initiatives focus on health and independence, there exists a gap in structured activities for older persons. Our study introduces MyHOeME, a 5-week program designed by an occupational therapist, which addresses the physical, cognitive, and social facets of ageing through personalized activities. This quasi-experimental study involved 78 older persons in the community. The results indicate a significantly enhanced health-related quality of life after attending MyHOeME, emerging as a promising solution for the well-being of Malaysia's ageing population.
Effects of Core Stability Training on Muscle Physiology among Adults with Low Back Pain
Authors: Pipeng Lin , Zahari Zarina , Azizan Azliyana , Yajun Yang 
Published: March 2024

Background: The effects of core stability training (CST) on muscle physiology in adults with chronic low back pain(CLBP) are still debatable. Objectives: To explore the effects of CST on muscle physiology in adults with CLBP. Methods: Eligible studies published in English from inception to October 2023 were extracted from PubMed, Web of Science, and Scopus in this review. Pedro was used for scoring and followed the PRISMA guidelines. Findings: Core muscle strength (1 study), thickness (4 studies), and activation (6 studies) favored CST. Conclusion: CST was more effective in improving core muscle strength, and activation for patients with CLBP.
Breaking the Glass Code : Mentorship-Driven Empowerment in Malaysia’s ICT Sector
Authors: Shaari Noremi , Subramaniam Geetha , Rosnan Herwina , Ramli Suriana , Premananto Gancar Candra 
Published: March 2024

This study explores the role of mentoring in advancing women’s careers in Malaysia's ICT sector, where women are underrepresented in leadership roles. This conceptual study is primarily centered on examining the role of mentorship in advancing women's careers in Malaysia's Information and Communication Technology (ICT) sector. It examines societal, organizational, work-life balance, and individual factors influencing the career paths of women in the ICT sector in Malaysia. This study is significant in providing the importance of promoting diversity in the workforce, in line with the Sustainable Development Goal SDG 5 i.e. Gender Equality.
The Role of Local Champion in Achieving an Integrated Rural Tourism: A Case Study of Alamendah Tourism Village, West Java
Authors: Andari Rini , Hudaiby Galih Kusumah Ahmad , Ningsih Caria 
Published: March 2024

Integrated rural tourism can provide welfare to the community and materialize the concept of sustainable tourism. The development carried out to achieve this requires synergy between the internal and external stakeholders. This study analyzes the role of local champions in achieving integrated rural tourism. This research uses a qualitative approach with a case study method to explore cases or phenomena that are interrelated to determine their uniqueness. The tourist village explored is Alamendah which has an ADWI (Anugerah Desa Wisata Indonesia) award 2021 from the government, the selection of this tourist village can be a guide for other tourist villages with a desire to grow. According to the findings of this study, the role of the chairman of the village, who is responsible for managing tourism in the village and acts as a local champion in establishing integrated rural tourism, is essential. Tourist villages also require leaders from their communities who can be trusted and influential in uniting their goals and mission.
Morpho-Physiological Responses of Malabayabas (Tristaniopsis decorticata (Merr.) Peter G. Wilson & J.T. Waterh.) Seedlings Inoculated with Arbuscular Mycorrhizal Fungi
Authors: Corbita Victor Lobrigas , Combalicer Marilyn Sabalvaro , Manalo Mutya Ma Quintos , Galang Marco Aragones , Maldia Lerma San Jose 
Published: March 2024

Malabayabas (Tristaniopsis decorticata (Merr.) Peter G. Wilson & J.T. Waterh.) of the Myrtaceae family is a vulnerable endemic tree species in the Philippines. Poor development and low regeneration rates of seedlings in their natural habitats have led to a considerable population decline of the species. This study aimed to determine the morphological and physiological growth responses of T. decorticata seedlings in different soil media inoculated with arbuscular mycorrhizal fungi applied once at a rate of 5 g per seedling for the entire duration of the experiment. Morphological parameters were collected using conventional methods, while physiological parameters were measured using LI-6400 XT Portable Photosynthesis System. Results of the study revealed that the morphological growth of seedlings was generally better in Bantay soil regardless of treatments than in Lipa soil. Interestingly, the net photosynthesis, transpiration rate, and water-use efficiency were generally higher in Lipa unsterilized soil inoculated with arbuscular mycorrhizal fungi. However, this study can not yet confirm the percentage of Arbuscular Mycorrhizal Fungi (AMF) root colonization. Thus, further research must be conducted to determine the AMF root colonization and identify potential indigenous mycorrhizal fungi in both soil media.
Keywords: arbuscular mycorrhizal fungi, endemic, net photosynthesis, transpiration rate, Tristanipsis decorticata
Modeling Land Cover Change Using MOLUSCE in Kahayan Tengah Forest Management Unit, Kalimantan Tengah
Authors: Iskandar Beni , Saidah  , Kurnia Adib Ahmad , Jauhari Ahmad , Zannah Fathul 
Published: March 2024

A management unit-based land cover change analysis was examined in Kahayan Tengah Forest Management Unit (FMU) to understand past, present, and future land cover to assist forest management planning in Kahayan Tengah FMU. This study aims to model land cover change in 2011 and 2016, predict 2021, and simulate land cover in 2026 in Kahayan Tengah FMU. Modeling land cover prediction and simulation using MOLUSCE from the QGIS plugin. The results revealed that agricultural land experienced significant increase in total area during 2011–2016. Modeling potential land cover transitions in 2011 and 2016 with the Artificial Neural Network method showed a Kappa coefficient of 0.701 in the good category, and simulation of land cover in 2021 with the Cellular Automata method showed a Kappa coefficient of 0.672 in the good category. By 2026, the agricultural land will continue to increase while forest land tends to remain stable in its total area. This study managed to predict land cover in 2021 and simulated 2026 with good accuracy. Thus, this data and information can support forest management planning in Kahayan Tengah FMU.
Keywords: forest management unit, Kahayan Tengah, land cover change, land cover prediction, MOLUSCE
Pengaruh Model Pembelajaran Sains Teknologi Masyarakat dalam Meningkatkan Motivasi Belajar Kimia pada Materi Koloid
Authors: Wulandari Lusi , Octarya Zona 
Published: March 2024

This research was instigated with the low of student chemistry learning motivation. It aimed at finding out whether there was a difference of chemistry learning motivation between students taught by using Science Technology Society learning model and those who were not taught by using Science Technology Society learning model. It was quantitative research with quasi-experiment method. The samples of this research were the eleventh-grade students of MIA 2 and 4, and they were 72 students. Questionnaire and documentation were used to collect data. Independent sample t-test was the technique of analyzing data. Based on data analysis results, there was a difference of chemistry learning motivation between students taught by using Science Technology Society learning model and those who were taught by using conventional learning model on Colloid lesson at State Islamic Senior High School 3 Pekanbaru. It was proven with the score of tobserved higher than ttable at 5% significant level (4.587>1.994). Based on the result of effect size test by using Cohen’s formula, the score of d 2.59 was lower than 1, and it meant that Science Technology Society learning model affected student chemistry learning motivation significantly.
Tata Laksana Infertilitas yang Rasional dan Efisien untuk Mempersingkat "Time to Pregnancy"
Authors: Bayuaji Hartanto 
Published: March 2024

AbstrakTujuan: Memberikan pandangan kepentingan melakukan penatalaksanaan infertilitas yang efisien untuk mempersingkat time to pregnancy.Metode: Telaah pustaka dan basis bukti.Hasil: Kunci mempersingkat time to pregnancy pada penanganan infertilitas adalah melakukan work-up yang efisien dan rasional. Terdapat beberapa pemeriksaan yang mempunyai manfaat jelas berdasarkan basis bukti. Hari-hari tertentu pada siklus menstruasi seorang wanita dapat dimanfaatkan untuk melakukan beberapa pemeriksaan terpilih. Fokus pemeriksaan adalah identifikasi latar belakang kesehatan suami dan istri, mengetahui adanya ovulasi dan cadangan ovarium, tes patensi tuba, evaluasi anatomik uterus dan peritoneum, serta analisis sperma. Setelah data dasar tersebut diperoleh, dilakukan evaluasi komprehensif untuk mengetahui program penanganan yang sesuai. Saat ini telah terdapat panduan nasional praktik kedokteran penanganan infertilitas sebagai dasar untuk dapat menangani infertilitas secara efisien.Kesimpulan: Time to pregnancy dapat dipersingkat dengan proses diagnostik dan penanganan yang berbasis bukti dengan memanfaatkan waktu-waktu tertentu dari siklus menstruasi.Rational and Efficient Infertility Management Improve Shortening "Time to Pregnancy"AbstractObjective: Provide an insight of the importance of conducting efficient and rational infertility management to shorten time to pregnancy.Method: Literature and evidence base review.Results: The key to shortening time to pregnancy in infertility management is to do an efficient and rational work-up. There are several examination that have clear benefits. Certain days of a woman's menstrual cycle can be used to do some selected examinations. The focus of the examination is identification of the health background of husband and wife, ovulation documentation and ovarian reserve assay, tubal patency tests, anatomic evaluation of the uterus and peritoneum, and sperm analysis. After the basic data is obtained, a comprehensive evaluation is carried out to find out the appropriate management program. Currently there is a national guide to the practice of medical treatment of infertility as a basis for infertility management efficiently.Conclusion: Time to pregnancy can be shortened by an evidence-based diagnostic and treatment process by utilizing certain times of the menstrual cycle.Key words: Infertility, time to pregnancy, infertility management, referral system.