bluuebunny/crossref_metadata_2025_split huggingface dataset:
Reconstruction of gluteal defects related to Nicolau Syndrome secondary to intramuscular injection of diclofenac sodium with negative pressure wound therapy followed by skin graft.
Authors: Kokacya Omer , Tabakan Ibrahim , Gencel Eyuphan , Eser Cengiz 
Published: February 2025

Objective: Nicolau syndrome, synonymously livedo-like dermatitis or embolia cutis medicamentosa is a rare complication of drug injection leading to locoregional necrosis of the skin, adipose and muscular tissue. Underlying physiopathology is not well unserstood and there is no standart guideline for its management. However, after the demarcation of necrosis, debridement and for large wounds reconstruction is mandatory. Even though vast majority of the Nicolau syndrome cases were reported by other disciplines but the plastic surgery, there may be further need for reconstructive procedures for wound closure.
Material and Methods: Present study included eight patients admitted to our wound care center for necrosis at the gluteal region after intramuscular injection of diclofenac sodium who were treated with debridement, negative pressure wound therapy and skin grafts. Patients’ ages, genders, body mass indexes, underlying diseases were documented. Sizes of the lesions were measured. Injection, hospitalization, skin graft operation and discharge dates were recorded.
Results: All the wounds healed uneventfully but with depressed scars. Mean duration of hospitalization was 23.5 (range, 15-34) days.
Conclusion: In the present article, we reported that even if the hospitalization time is longer and cosmetic result is poorer, skin grafting after sufficient times of vacuum assited wound therapy administration is a reliable method. We do not recommend this method as the first choice but if there is not adequate adjacent soft tissue for harvesting flaps or if a suitable perforator vessel is not found for peforator flap harvest, this reliable method should be kept in mind.
A Retrospective Analysis on the Use of Algorithm for the Diagnosis of Mycobacterium Tuberculosis
Authors: Guducuoglu Huseyin , Bektas Abdullah , Keskin Siddik , Ragbetli Cennet 
Published: February 2025

Objective: The aim of this study was to investigate whether an algorithm has been used for the diagnosis of Mycobacterium tuberculosis samples over the last three years.
Material and Methods: A total of 1,036 samples collected between June 2010 and March 2013 were submitted to the laboratory for the diagnosis of Mycobacterium tuberculosis. The samples were studied using the Ehrlich-Ziehl-Neelsen (EZN) staining. Various culture methods such as Löwenstein-Jensen (LJ) medium-BacT/ALERT® 3D and the BD BACTEC™ MGIT™ 320 Mycobacteria Culture System were applied for 508 samples. Real-time Polymerase Chain Reaction (PCR) method was performed in 138 samples. In general, 2 or 3 samples were obtained from each patient for the diagnosis of acid-fast bacilli (AFB), whereas only one sample was obtained for culture.
Result: Of the EZN-positive samples, 30% were PCR-positive and 65% were culture-positive; of the culture-positive samples, 13% were PCR-positive and 54% were EZN-positive; of the PCR-positive samples, 21% were culture-positive and 43% were EZN-positive.
Conclusion: AFB and culture are likely to be inadequate for the determination of Mycobacterium tuberculosis. Therefore, PCR seems to be an essential need. However, the clinical table of the patient should also be considered to determine the need for PCR. Thus, an appropriate algorithm should be suggested for the diagnosis of Mycobacterium tuberculosis.
Comparison of the effects of two different dose algorithms in cardiac dose parameters for hodgkin lymphoma patients receiving mediastinal radiotheraphy
Authors: Tahberer Emre , Adigul Mehmet , Capar Ahmet Ergin , Cinkaya Ahmet , Coban Yasin , Surenkok Serdar 
Published: February 2025

Objective: This study aimed to compare pencil beam (PB) and convolution superposition (CS) dose calculation algorithms with respect to cardiac dose-volume parameters V5, V25, V30 and MHD (median heart dose) in Hodgkin lymphoma (HL) patients who received mediastinal radiotherapy (RT).
Material and Methods: Ten eligible cases with the diagnosis of HL who completed mediastinal RT at Dokuz Eylül University Department of Radiation Oncology before 01.01.2011 formed the study population. Related 3D conformal RT treatment plans were obtained from the Treatment Planning System (TPS) (Nucletron Oncentra Master Plan Version 3.3 SP3 program). Calculations were done for 6 and 18 MV-X beam energy, respectively by using PB and CS algorithms in the TPS. Two algorithms were compared in terms of cardiac dose-volume parameters (V5, V25, V30 and MHD).
Results: Mean relative difference for both V25 and V30 was found to be significantly higher in favor of PB algorithm in both 6 MV-X and 18 MV-X photon energy. Mean relative differences were 1.75% (p=0.012) and 6.76% (p=0.028) for the V25 and V30 parameters, respectively in 6 MV-X and 3.25% (p=0.021) and 13.95% (p=0.007) for the V25 and V30 parameters, respectively in 18 MV-X energy.
Conclusion: When PB algorithm is used in RT treatment planning of HL patients for the mediastinal region where tissue inhomogeneity is relatively high, heart V25 and V30 parameters were shown to result in higher values compared to CS algorithm in our study. It is more appropriate to prefer CS algorithm instead of PB algorithm since it increases accuracy of calculations in the treatment planning of mediastinal RT.
Investigation of Serum Enzyme Activity of Nitric Oxide (NO), Arylesterase (ARE) and Paraoxanase (PON) in Renal Tumors
Authors: Gur Tugba Gur , Enterili Gulsen , Pirincci Necip , Demir Canan , Demir Halit , Kaba Mehmet , Eren Huseyin 
Published: February 2025

Objective: Reactive oxygen species (ROS) and antioxidant capacity have been implicated in the pathogenesis of various diseases, and cancers. Oxidative stress can cause tumor angiogenesis and may be carcinogenic. However, the relationship between antioxidant capacity and various cancers has been researched in several clinical trials.
Materials and Methods: In this study, we aimed to identify serum Nitric Oxide (NO), Arylesterase (ARE) and paraoxonase (PON) activities in patients with renal tumors. Serum ARE, PON and NO levels were measured by spectrophotometer.
Results: Increased activity of serum nitric oxide (NO) was determined in cancer group. Serum Arylesterase (ARE) were significantly lower in the patient group than the control group. Increased activity of Serum paraoxonase (PON) were detected in the control group (p < 0.05).
Conclusion: Our results indicates that Nitric oxide (NO), arylesterase (ARE) and paraoxonase (PON) activities may play an important role in the pathogenesis of renal cell cancer.
Pattern of chronic myeloid leukemia in the Congo
Authors: Ngolet Lydie Ocini , Malanda Felix , Dokekias Alexis Elira 
Published: February 2025

Objectives: Chronic myeloid leukemia is a clonal myeloproliférative disorder caused by reciprocal translocation t (9;22) that induces tyrosin kinase protein. Imatinib is a selective inhibitor of this protein. Aim of this study is to describe, the clinical and biological feature of chronic myeloid leukemia in the Congo.
Material and Methods: The study is a retrospective study which conducted in Clinical Hematology unit of teaching hospital in Brazzaville, Congo on newly diagnosed patients with chronic myeloid leukemia. A total of 25 males and 14 females with a mean age of 36 years (16 and 69 years) at time of the diagnosis were enrolled in the study.
Results: The mean duration of the illness at the time of the diagnosis was 11.4 months (0.5 and 50 months). Patients presented with a splenomegaly, mean leukocytosis rate at 168.5g/l (14.6-381 g/l), moderate anemia at 8.4 g/dl (3.1 and 12.8 g/dl) and normal platelet rate at 415.4 g/dl (164 and 998 g/l). Thirty eight on thirty nine patients (97.43 %) presented at chronic phase and the Sokal score was high in 46.2%. Imatinib induced complete hematologic response at 3 months in all patients. Complete cytogenetic response was achieved in 20.51%. The median follow up period was months. The Overall Survival was 86.6% at 26 months and Progression Free Survival was 91.8% at 12 months.
Conclusion: This meta analysis report represents the clinical and biological pattern of chronic myeloid leukemia in the Congo.
EFEKTIVITAS METODE PENGAJARAN PENCAK SILAT DALAM MENINGKATKAN DISIPLIN DAN KARAKTER MAHASISWA
Authors: Jasmani  , Iwan Arya Kusuma  , Slamet Sudarsono  , Risa Agus Teguh Wibowo  , Muchhamad Sholeh  , Bintang Qori Az Zahra  
Published: February 2025

Penelitian ini bertujuan untuk mengkaji Efektivitas Metode Pengajaran Pencak Silat dalam Meningkatkan Disiplin dan Karakter Mahasiswa. Pencak silat, sebagai salah satu seni bela diri tradisional, tidak hanya melatih kemampuan fisik, tetapi juga diyakini memiliki peran dalam membentuk kepribadian dan perilaku disiplin individu. Penelitian ini menggunakan pendekatan kualitatif dengan observasi, wawancara dan dokumentasi kepada mahasiswa yang mengikuti pelatihan pencak silat. Indikator yang diukur meliputi disiplin yang mencakup ketaatan pada peraturan, konsistensi latihan, manajemen waktu, kedisiplinan akademik, dan kemampuan mengontrol emosi. Sementara itu, aspek karakter yang dinilai meliputi tanggung jawab, kerjasama, kejujuran, keberanian, serta rasa hormat dan empati. Hasil penelitian menunjukkan bahwa metode pengajaran pencak silat efektif dalam meningkatkan perilaku disiplin mahasiswa, yang tercermin dari peningkatan ketaatan terhadap peraturan, konsistensi dalam latihan, dan kemampuan dalam mengelola waktu. Selain itu, karakter mahasiswa seperti tanggung jawab, kejujuran, dan kerjasama juga berkembang secara signifikan. Mahasiswa yang mengikuti pelatihan pencak silat juga mengalami peningkatan dalam ketahanan fisik dan keseimbangan emosi. Dengan demikian, pencak silat dapat dianggap sebagai metode yang efektif untuk membentuk disiplin dan karakter mahasiswa secara holistik.
Kata Kunci: pencak silat, disiplin, karakter
Mulching effects on the quality formation of medicinal materials and rhizosphere soil microenvironment in
Notopterygium franchetii
in the Qinghai-Tibet Plateau
Authors: Xu Shengrong , Ma Ruili , Yang Shibing , La Taijia , Nan Xingmei , Kang Wenjuan 
Published: February 2025

ABSTRACT
Different cultivation methods directly affect the quality of medicinal materials, to gain insights into the effects of different type of mulching on the quality of Notopterygium franchetii root medicinal materials, farmland experiments were conducted in the Qinghai-Tibet Plateau. We subjected two-year-old Notopterygium franchetii seedling to five mulching treatments: no mulching (CK, control), coarse sand mulching (CM), grassy mulching (GM), stalk mulching (SM), and plastic mulching (PM). Following these treatments, we determined the moisture content, pH, NPK contents, and enzymeatic activity of the soil, and morphological indexes and content of the main components of root. Stalk mulching and PM increased the main root biomass by increasing its ground diameter and reduced branched root biomass by reducing the number of branched roots produced. Grassy mulching increased the root biomass by promoting main root elongation. Mulching increased the total content of the six main root components, with the most significant change obtained with GM, but the pattern of change of the different components varied among the mulch treatments. Contents of NPK were significantly higher than in the control with GM, but decreased with PM. Coarse sand mulching and PM significantly reduced the activities of urease and sucrase, and SM significantly increased the activities of urease, catalase and sucrase, but significantly decreased that of phosphatase. Furthermore, GM significantly increased phosphatase and sucrase activities, while CM significantly decreased urease and sucrase activities. Various soil enzymes and its pH promote main root bioaccumulation by increasing the root ground diameter or main root length. Sucrase activity promoted the accumulation of ferulic acid, psoralen, and notopterol content, and inhibited the accumulation of chlorogenic acid and nodakenin. Elevated soil water content promoted the accumulation of ferulic acid, notopterol and nodakenin, and inhibited isoimperatorin accumulation. Hence, NPK, pH, and various enzymes have different effects on the accumulation of major components in the root. The effect of mulching is closely linked to root growth and distribution, as well as to the soil environment. Various soil factors affect the quality of medicinal materials differently and, ultimately, can work together to form an equilibrium state that benefit the accumulation of main root biomass and main components with medicinal interest in Notopterygium franchetii.
Recenzje książek
Authors: Kośmicki Eugeniusz 
Published: February 2025

Recenzje książek

Claudia Lanfranconi, Sabine Frank, Die Damen mit dem grünen Daumen. Berühmte Gärtnerinnen (Damy z zielonymi palcami. Sławne ogrodniczki), ss. 159, 3 Aufl., Berlin 2020, Elisabeth Sandmann im Insel Verlag (insel taschenbuch 4222), ISBN 978-3-458-35922-7, www.insel-verlag.de

Herta Simon, Jürgen Becker, Marion Nickig, Das grosse GU Gartenbuch. Das Standar- dwerk für jeden Gartenliebhaber, (Duża księga ogrodnicza, Wydawnictwa Gräfe und Un- zer. Dzieło wzorcowe dla każdego miłośnika ogrodów), 560 Farbfotos von Jürgen Becker und Marion Nickig, 300 Farbzeichnungen von György Jankovic, ss. 320, 13., Auflage, München 2022, Gräfe und Unzer Verlag GmbH, ISBN 978-3-8338-5392-0, www.gu.de

Burkhard Bohne, Achtung Giftpflanze! 160 Garten- und Wildpflanzen einfach erkennen. Mehr Sicherheit für Kind u. Haustier. (Uwaga roślina trująca! 160 roślin ogrodowych i rosnących dziko łatwo rozpoznawać. Więcej bezpieczeństwa dla dzieci i zwierząt domowych), 164 barwne fotografie, ss. 128, Stuttgart (Hohenheim) 2022, ISBN 978-3-8186-1624-3, www.ulmer.de
Tecnología en las Inteligencias Múltiples: Fortalecimiento del Aprendizaje mediante los Estilos VAK (Visual, Auditivo, Quinestésico) y Metacognitivo en la Enseñanza de Matemáticas
Authors: Paucar Tinajero Pablo Patricio , Casa Mayorga Susana Alexandra , Rodríguez Pacheco Pamela Alexandra , Tipán López Edilma Piedad , Cóndor Lara Lina María 
Published: February 2025

En el sistema formativo actual, la incorporación de la virtualidad es fundamental para mejorar la enseñanza, considerando que facilita la personalización del proceso educativo, permitiendo atender las necesidades individuales de los estudiantes según sus fortalezas cognitivas. Objetivo, se propone, investigar la importancia del uso de la tecnología en las Inteligencias Múltiples, los estilos de aprendizaje VAK (Visual, Auditivo, Quinestésico) y Metacognitivo en la Enseñanza de Matemáticas. Metodología. La investigación emplea un enfoque cuantitativo y cualitativo, se efectúa una revisión de literatura para fundamentar teóricamente, se diagnostican las dificultades en operaciones básicas, pruebas, la observación y encuestas; los datos obtenidos se analizan estadísticamente indicando que el 60% de los educandos reporta el uso ocasional de dispositivos tecnológicos por parte de los docentes, y el 52% asimila conceptos mediante multimedia. Conclusiones. Existen oportunidades significativas para la asimilación de contenidos. Además, un 49% utiliza internet ocasionalmente, y un 17% muestra falta de acceso a herramientas digitales al respecto la utilización de la digitalización prepara a los alumnos para enfrentar desafíos futuros con una base sólida de conocimientos y habilidades, influyendo en la formación inclusiva y equitativa, que valora y potencia las diferentes formas de aprender. Resultados, los maestros apoyan al estudiantado a planificar, monitorear y evaluar sus métodos de estudio utilizando diagramas, explicaciones orales, recursos sonoros, actividades prácticas y manipulativas orientados a la comprensión, retención de la información, motivación, participación, autonomía y rendimiento académico.
Mejoría Clínica de Pacientes Operados de Cadera por Pinzamiento Femoroacetabular Mediante Artroscopia en el Centro Médico Naval
Authors: Sanchez  Sinto Juan Sebastian , Murillo Dominguez Sergio Esau 
Published: February 2025

Objetivo: El objetivo de este estudio es determinar si los pacientes que se someten a artroscopía de cadera por diagnóstico de pinzamiento femoroacetabular experimentan un cambio estadísticamente significativo al comprar su funcionalidad en actividades de la vida diaria, deportivas y en general antes y después de una cirugía de artroscopia. Métodos: Se analizaron un total de 12 pacientes, obtenidos de los registros de pacientes intervenidos por artroscopia de cadera entre los años 2015 y 2024, que contaran con evaluación preoperatoria y seguimiento postoperatorio mediante aplicación de encuestas de al menos 1 año con las subescalas actividades de la vida diaria (ADL) y actividades deportivas (SS) de la escala Hip Outcome Score (HOS), y la escala de funcionalidad modificada Harris Hip Score (mHHS). Resultados: Se analizaron 12 pacientes, de estos cinco fueron de sexo femenino (42%) y 7 masculino (58%), con una edad media de 46.5 ± 14.1años, con un índice de masa corporal de 26.25 ± 3.04 kg/m2, 17. Se analizaron, además, características propias indicativas del grado de actividad con relación al estatus de régimen civil o militar. En cuanto al ámbito militar se incluyeron diez pacientes (83%) y solo dos civiles (17%); por último, se consideró el tipo de pinzamiento de cadera más frecuente como indicación para realizar este procedimiento. El tipo más frecuente fue el tipo Cam con seis individuos (50%), seguido de Pincer con cuatro individuos (33%) y dos tuvieron un pinzamiento mixto (17%). Los pacientes experimetaron mejoria significativa posterior a cirugia artroscopica de cadera. Los pacientes experimetaron mejoria significativa para las escalas HOS-ADL, HOS-SS y MHHS ( P<0.005). MCID fue logrado en 83.3% de los pacientes para HOS-ADL, 91.6% para HOS-SS y 83.3% para MHHS. PASS fue logrado para el 41.6% para HOS-ADL, 41.6% para HOS-SS y 58% para MHHS.Conclusiones: Se observó que los pacientes luego de al menos 1 año de operados de artroscopia de cadera por pinzamiento femoroacetabular mejoraron considerablemente. El tratamiento artroscópico en los pacientes con diagnóstico de pinzamiento femoroacetabular es eficaz y seguro. Por lo que se recomienda realizar este procedimiento para todos aquellos pacientes que sean captados con este diagnóstico y así evitar las consecuencias limitantes que este padecimiento puede generar a largo plazo.
Marca-passo sem eletrodos em pacientes com doença renal crônica e hemodiálise
Authors: Sousa André Maroccolo , Oliveira Vinícius Martins Rodrigues , Oliveira Izadora Caiado , Menezes Junior Antônio da Silva 
Published: February 2025

Introdução: A doença renal crônica (DRC) é uma condição de saúde global que afeta aproximadamente 10% da população adulta e está associada a alta morbidade e mortalidade. Portadores de DRC apresentam maior risco de desenvolver doenças cardiovasculares e distúrbios do ritmo cardíaco, com a necessidade da implantação de marca-passo. O marca-passo sem eletrodos tem sido estudado em diversas populações e apresenta vantagens em relação aos dispositivos tradicionais. Entretanto, a eficácia e segurança do uso de marca-passos sem eletrodos nessa população permanecem incertas. Objetivo: Este estudo objetiva mapear a literatura existente acerca do uso do marca-passo sem eletrodos em pacientes com DRC em hemodiálise, abordando aspectos de eficácia, segurança e fatores relacionados à sua adoção na prática clínica. Metodologia: Realizouse uma revisão de escopo, seguindo o protocolo PRISMA. Foram feitas buscas nas bases de dados PubMed, Embase, Scopus, Cochrane Library e CINAHL, abrangendo estudos que abordassem marca-passo sem eletrodos, doença renal crônica e hemodiálise. Foram incluídos artigos em inglês, português e espanhol, sem restrição temporal. Resultados: Foram encontrados 230 artigos durante a busca inicial. Após a exclusão de duplicatas, 165 estudos restaram e foram analisados por seus títulos e resumos. Após análise, 25 artigos foram considerados elegíveis para leitura do texto na íntegra e aplicação dos critérios de elegibilidade. Após leitura, 15 estudos foram incluídos nesta revisão. Os tipos de estudo encontrados foram: 7 (46,6%) relatos de caso, 6 (40%) estudos observacionais, 1 (6,6%) comentário editorial e 1 (6,6%) um artigo de revisão. Dentre os estudos, 7 (46,6%) concluíram que o marca-passo sem eletrodo está associado a melhora nos desfechos clínicos quando comparado ao marca-passo transvenoso em pacientes portadores de DRC e em hemodiálise devido à falência de acessos vasculares e pelo maior risco de infecção nesta população. 1 (6,6%) estudo demonstrou a associação do marca-passo sem eletrodos a uma maior taxa de complicações peri e pós-implantação precoce quando comparado ao convencional. Conclusão: Os resultados desta revisão de escopo sugerem que o marca-passo sem eletrodos apresenta-se como uma alternativa eficaz e com maior perfil de segurança a médio e longo prazo quando comparados aos dispositivos convencionais em pacientes com DRC e em hemodiálise. Entretanto, a literatura ainda mostra-se conflitante quanto a segurança no período peri e pós-implantação precoce, sendo necessários estudos futuros para maior compreensão da temática.
Semianalytical Fokker–Planck Models for Nuclear Star Clusters
Authors: Kaur Karamveer , Rom Barak , Sari Re’em 
Published: February 2025

Abstract
We study the dynamics of nuclear star clusters, the dense stellar environments surrounding massive black holes in the centers of galaxies. We consider angular momentum diffusion due to two-body scatterings among stellar objects and energy advection due to gravitational-wave emission upon interaction with the central massive black hole. Such dynamics are described by a 2D Fokker–Planck (FP) equation in energy–angular momentum space. Focusing on the transition between the diffusion-dominated region and the advection-dominated one, we utilize self-similarity to obtain a full solution for the steady-state FP equation. This solution provides the density and flux of the stellar objects in nuclear star clusters. This improves the rate estimates for extreme-mass ratio inspirals, and has interesting implications for a new class of galactic center transients called quasiperiodic eruptions.