bluuebunny/crossref_metadata_2025_split huggingface dataset:
A market and policy interpretation of recent developments in the world ethanol industry
Authors: Gallagher Paul W. 
Published: September 2007

AbstractThe concept of an integrated world ethanol market refers more to a possibility than to a reality. Presently, the value of ethanol exchanged among countries is only a few billion dollars. But the possibility of trade is real in the aftermath of escalating gasoline prices and the worldwide investment boom in ethanol. However, the prospects for continued investment and growth during the next five or six years are uncertain. This perspective considers some important factors that will define the extent of expansion in worldwide ethanol production and trade. Specifically, the balance between impending processing plans and possible technical limits on ethanol use in gasoline is measured. Also, commercial policies, such as subsidies, tariffs, and trade preferences that influence trade are reviewed; a few policies are also evaluated; and an import policy change for the EU and USA that accommodates growing developed country markets while promoting import diversification and economic development, is discussed. © 2007 Society of Chemical Industry and John Wiley & Sons, Ltd
Clinical outcomes of dexamethasone‐eluting stent implantation in ST‐elevation acute myocardial infarction
Authors: Jimenez‐Valero Santiago , Santos Belen , Pajin Fernando , Canton Tomas , Lazaro Esther , Moreu Jose , Hernandez Gonzalo , Padial Luis Rodriguez 
Published: September 2007

AbstractObjectives:The aim of our study was to evaluate the safety and midterm clinical results of dexamethasone‐eluting stent (DexES) implantation in ST‐segment elevation acute myocardial infarction (STEMI).Background:Inflammation plays a pivotal role in both inestabilization of coronary atherosclerotic plaques and development of restenosis after stent placement. Antiinflammatory agents may attenuate those mechanisms and improve clinical outcomes. There is little information about clinical results of DexES and no data are available about their utilization during percutaneous coronary intervention (PCI) in STEMI.Methods:Consecutive patients with STEMI that underwent primary or rescue PCI in our institution were treated with DexES. Clinical follow‐up with routine realization of noninvasive test for detection of myocardial ischemia and coronariography if necessary, were performed. The objective of the study was to evaluate the rate of MACE (death, reinfarction, or target lesion revascularization) during midterm follow‐up.Results:The procedure was successful in 96.7% of cases. There were no in‐hospital deaths or reinfarctions. One acute stent thrombosis occurred and no subacute thrombosis were observed. During a mean follow‐up period of 384 days, cardiac‐related death was 1.1%, there were no reinfarctions or late stent thrombosis and target lesion revascularization rate was 4.2%.Conclusion:We conclude that utilization of DexES for PCI in STEMI is safe and provides good midterm clinical outcomes. © 2007 Wiley‐Liss, Inc.
On‐site immediate removal of intraortic ballon pump after high‐risk percutaneous intervention with a 6 F closure suture device with the “preclosure” technique
Authors: Lozano Iñigo , Avanzas Pablo , Moris Cesar 
Published: September 2007

AbstractIntroductionIntraaortic balloon counterpulsation (IABP) may be necessary during percutaneous intervention (PCI) and sometimes it would be useful to withdraw it at the end of procedure. We describe the utility of a closure suture device to retrieve the IABP in the cardiac catheterization laboratory immediately after the intervention.MethodsObservational study of nine consecutive high‐risk PCI where an 8.5 F IABP had been retrieved at the end of the procedure with a 6 F Perclose™ with the “preclosure” technique. The baseline clinical characteristics as well as the in‐hospital and 90‐days follow‐up are described.ResultsThe patients age was 67.4 ± 14.9 years (mean 45–85; three patients were >80; 3 females (33.3%). Left main coronary artery was the target lesion in 8 (88.8%) and 4 (44.4%) patients, performed by radial access. Abciximab was used in 7 patients (77.7%). Successful hemostasis was achieved in all the cases without manual or mechanical compression. Only one patient was transferred to the Coronary Care Unit due to advanced age, left main coronary artery stenting, and severe ventricular dysfunction. Five patients (55.5%) were discharged 24 h after the PCI, three (33.3%) 48 h, and only one remained 72 h after the procedure. There were no events in the 90‐days follow‐up.ConclusionsThe “preclosure” technique with the 6 F Perclose™ is an ingenious approach to achieve successful hemostasis after IABP removal. It may permit to transfer the patients to units without critical care facilities, shorten the admission and reduce vascular complications in patients with peripheral vascular disease who may need the counterpulsation only during the percutaneous intervention. © 2007 Wiley‐Liss, Inc.
Effects of left ventricular unloading by Impella recover LP2.5 on coronary hemodynamics
Authors: Remmelink Maurice , Sjauw Krischan D. , Henriques José P.S. , de Winter Robbert J. , Koch Karel T. , van der Schaaf René J. , Vis Marije M. , Tijssen Jan G.P. , Piek Jan J. , Baan Jan 
Published: September 2007

AbstractObjectives:We studied the effects of LV unloading by the Impella on coronary hemodynamics by simultaneously measuring intracoronary pressure and flow and the derived parameters fractional flow reserve (FFR), coronary flow velocity reserve (CFVR), and coronary microvascular resistance (MR).Background:Patients with compromised left ventricular (LV) function undergoing high‐risk percutaneous coronary intervention (PCI) may benefit from LV unloading. Limited information is available on the effects of LV unloading on coronary hemodynamics.Methods:Eleven patients (mean LV ejection fraction of 35 ± 11%) underwent PCI during LV support by the LV unloading device (Impella Recover® LP2.5). Intracoronary measurements were performed in a nonstenotic coronary artery after the PCI, before and after adenosine‐induced hyperemia at four different support levels (0–2.5 L/min).Results:Aortic and coronary pressure increased with increasing support levels, whereas FFR remained unchanged. Baseline flow velocity remained unchanged, while hyperemic flow velocity and CFVR increased significantly with increasing support levels (61 ± 24 to 72 ± 27 cm/sec, P = 0.001 and 1.88 ± 0.52 to 2.34 ± 0.63, P < 0.001 respectively). The difference between baseline MR and hyperemic MR significantly increased with increasing support levels (1.28 ± 1.32 to 1.89 ± 1.43 mm Hg cm−1 sec, P = 0.005).Conclusions:Unloading of the LV by the Impella increased aortic and intracoronary pressure, hyperemic flow velocity and CFVR, and decreased MR. The Impella‐induced increase in coronary flow, probably results from both an increased perfusion pressure and a decreased LV volume‐related intramyocardial resistance. © 2007 Wiley‐Liss, Inc.
The SIRIUS‐DIRECT trial: A multi‐center study of direct stenting using the sirolimus‐eluting stent in patients with de novo native coronary artery lesions
Authors: Moses Jeffrey W. , Weisz Giora , Mishkel Gregory , Caputo Ronald , O'Shaughnessey Charles , Wong S. Chiu , Fischell Tim A. , Mooney Michael , Williams David O. , Popma Jeffrey J. , Fitzgerald Peter , Smith Sidney , Kuntz Richard E. , Collins Michael , Cohen Sidney A. , Leon Martin B. 
Published: September 2007

AbstractObjective:To assess the safety and efficacy of direct stenting using the sirolimus‐eluting BX Velocity™ stent in patients with coronary lesions.Background:Although direct coronary stenting has become a widespread practice, there have been no systematic assessments of direct stenting with drug‐eluting stents.Methods:Total of 225 patients with identical inclusion and exclusion criteria as the original SIRIUS trial were enrolled in this prospective single‐arm study. They were compared in a no‐inferiority design with 412 similar patients from the SIRIUS trial who had sirolimus‐eluting stents deployed after predilatation and were preassigned to angiographic follow‐up evaluation.Results:Direct stenting was successful in 85.8% of the patients. Compared with the predilatation group, direct stenting was associated with shorter median procedure duration (33 min vs. 45 min, P < 0.001). Angiographic follow‐up at 8 months revealed similar late loss (in‐stent—0.19 ± 0.47 mm vs. 0.17 ± 0.44 mm, and in‐lesion—0.23 ± 0.41 mm vs. 0.24 ± 0.47 mm) and similar frequency of binary restenosis (in‐stent—4.6% vs. 3.2% and in‐lesion—6.1% vs. 8.9%) between the two treatment strategies. However, stent‐edge restenosis was lower with direct stenting than in the predilatation control group (2.1% vs. 6.9%, P = 0.02). At 12‐months, there were no significant differences in target lesion revascularization (3.7% vs. 5.1%, P = ns) or composite major adverse cardiac events (7.0% vs. 8.3%, P = ns).Conclusions:In patients similar to those treated in the SIRIUS trial, direct stenting using sirolimus‐eluting stents achieves excellent short‐ and long‐term clinical and angiographic results with shorter procedure time and less frequent stent edge restenosis compared with predilation stent implantation techniques. © 2007 Wiley‐Liss, Inc.
Ferrocenylethynyl Derivatives of Nucleoside Triphosphates: Synthesis, Incorporation, Electrochemistry, and Bioanalytical Applications
Authors: Brázdilová Petra , Vrábel Milan , Pohl Radek , Pivoňková Hana , Havran Luděk , Hocek Michal , Fojta Miroslav 
Published: September 2007

AbstractModified dATP (2′‐deoxyadenosine‐5′‐triphosphate) and dUTP (2′‐deoxyuridine‐5′‐triphosphate) bearing ferrocene (Fc) labels linked via a conjugate acetylene spacer were prepared by single‐step aqueous‐phase cross‐coupling reactions of 7‐iodo‐7‐deaza‐dATP or 5‐iodo‐dUTP with ethynylferrocene. The Fc‐labeled dNTPs were good substrates for DNA polymerases and were efficiently incorporated to DNA by primer extension (PEX). Electrochemical analysis of the 2′‐deoxyribonucleoside triphosphates (dNTPs) and PEX products revealed significant differences in redox potentials of the Fc label bound either to U or to 7‐deazaA and between isolated dNTPs and conjugates incorporated to DNA. Prospective bioanalytical applications are outlined.
Evolution and persistence of the cilium
Authors: Satir Peter , Guerra Charles , Bell Aaron J. 
Published: September 2007

AbstractThe origin of cilia, a fundamental eukaryotic organelle, not present in prokaryotes, poses many problems, including the origins of motility and sensory function, the origins of nine‐fold symmetry, of basal bodies, and of transport and selective mechanisms involved in ciliogenesis. We propose the basis of ciliary origin to be a self‐assembly RNA enveloped virus that contains unique tubulin and tektin precursors. The virus becomes the centriole and basal body, which would account for the self‐assembly and self‐replicative properties of these organelles, in contrast to previous proposals of spirochaete origin or endogenous differentiation, which do not readily account for the centriole or its properties. The viral envelope evolves into a sensory bud. The host cell supplies the transport machinery and molecular motors to construct the axoneme. Polymerization of cytoplasmic microtubules in the 9 + 0 axoneme completes the 9 + 2 pattern. Cell Motil. Cytoskeleton 2007. © 2007 Wiley‐Liss, Inc.
Chordoma and chondrosarcoma: Similar, but quite different, skull base tumors
Authors: Almefty Kaith , Pravdenkova Svetlana , Colli Benedicto O. , Al‐Mefty Ossama , Gokden Murat 
Published: September 2007

AbstractBACKGROUNDChordoma and chondrosarcoma of the skull base are frequently amalgamated because of similar anatomic location, clinical presentation, and radiologic findings. The chondroid chordoma variant has been reported to carry a better prognosis. The objective of the current study was to investigate the distinctions between these 3 entities.METHODSThe data concerning 109 patients with chordoma, chondroid chordoma, and chondrosarcoma who were treated by a single surgeon with maximum surgical resection and frequently by adjunct proton beam radiotherapy between 1990 and 2006 were analyzed retrospectively. Pathologic distinction was established by cytokeratin and epithelial membrane antigen staining. Clinical, radiologic, pathologic, and cytogenetic studies were analyzed in relation to disease recurrence and death.RESULTSThe average follow‐up was 48 ± 37.5 months (range, 1–191 months). There were no reliable distinguishing clinical or radiologic features noted between the groups. Chondrosarcoma patients had a significantly better outcome compared with chordoma patients with regard to survival and recurrence‐free survival (P = .028 and P < .001, respectively), whereas patients with chondroid chordoma had a poor outcome similar to chordoma patients with regard to survival and recurrence‐free survival (P = .337 and P = .906, respectively).CONCLUSIONSChordoma and chondrosarcoma differ with regard to their origin and histology, and differ markedly with regard to outcome. Chondroid chordomas behave in a manner that is clinically similar to chordomas, with the same prognosis. Both chordoma types demonstrate an aggressive clinical course and poor outcome after disease recurrence. The optimal treatment for all groups of patients involves radical surgical resection followed by high‐dose radiotherapy in patients with chordomas. Radiotherapy may not be necessary in patients with low‐grade chondrosarcoma. Cancer 2007. © 2007 American Cancer Society.
Self‐inflicted bodily harm among victims of intimate‐partner violence
Authors: Sansone Randy A. , Chu Jamie , Wiederman Michael W. 
Published: September 2007

AbstractIn this study, we surveyed 113 women psychiatric inpatients with regard to histories of intimate‐partner violence and six self‐harm behaviours related to the intentional damage of one's body (e.g., cutting, hitting, scratching self). Multiple regression analysis revealed that a history of domestic violence was a statistically significant predictor of bodily self‐harm even after controlling for age and having ever been married. Among some victims of domestic violence, this statistical relationship may indicate an underlying common psychodynamic theme such as a high threshold for body maltreatment and/or low body esteem. Regardless, these data suggest that mental health clinicians need to explore among women victims of intimate‐partner violence the presence of self‐initiated bodily self‐harm. Copyright © 2007 John Wiley & Sons, Ltd.
Paranoid beliefs and self‐criticism in students
Authors: Mills A. , Gilbert P. , Bellew R. , McEwan K. , Gale C. 
Published: September 2007

AbstractParanoid beliefs are associated with negative and malevolent views of others. This study, however, explored hostile and compassionate self‐to‐self relating in regard to paranoid beliefs. A total of 131 students were given a series of scales measuring paranoid ideation, forms and functions of self‐criticism, self‐reassurance, self‐compassion and depression. Test scores were subjected to correlation and hierarchical regression analyses to explore the relative contribution of study variables to paranoid beliefs.In this population, paranoid beliefs were associated with forms and functions of self‐criticism, especially self‐hating and self‐persecution. Paranoid beliefs were negatively correlated with self‐kindness and abilities to be self‐reassuring. These variables were also associated with depression (as were paranoid beliefs). A hierarchical regression found that self‐hatred remained a predictor of paranoid ideation even after controlling for depression and self‐reassurance. Paranoid beliefs seem to be associated with a critical and even hating experience of self. These inner experiences of self may be profitable targets for therapeutic interventions. Copyright © 2007 John Wiley & Sons, Ltd.
Poor metacognition in Narcissistic and Avoidant Personality Disorders: four psychotherapy patients analysed using the Metacognition Assessment Scale
Authors: Dimaggio Giancarlo , Procacci Michele , Nicolò Giuseppe , Popolo Raffaele , Semerari Antonio , Carcione Antonino , Lysaker Paul Henry 
Published: September 2007

AbstractPersonality Disorders (PDs) are hypothesized to involve a decrement in the capacity to understand one's own thoughts and feelings. Patients may not, for example, recognize their own emotions or put together integrated representations of self with other. Some researchers have suggested that this deficit varies between the different PDs. However, empirical evidence that might confirm or disconfirm this hypothesis is scarce. The goal of the present research is to evaluate the metacognitive capacity in four participants, two with Narcissistic Personality Disorder and two with Avoidant Personality Disorder. Using the Metacognition Assessment Scale to analyse the transcripts of their first year of psychotherapy, we have found that three of the four participants displayed difficulties in recognizing their inner states and in linking them to the environmental and psychological causes behind them. There was, additionally, a milder deficit in the ability to integrate multiple images of self with other. Copyright © 2007 John Wiley & Sons, Ltd.
Investigating the phenomenology of Borderline Personality Disorder with the States Description Procedure: clinical implications
Authors: Ryle Anthony 
Published: September 2007

AbstractPatients with Borderline Personality Disorder (BPD) manifest major discontinuities in their experience and behaviour, and these contribute to the difficulties of clinicians seeking to treat them. The underlying problem is one of structural dissociation of self processes into a small range of distinct states, the switches between which can be abrupt and evidently unprovoked.A method of guided introspection, the States Description Procedure (Revised) (SDP‐R), is described. The SDP‐R provides a list of commonly used titles and brief profiles of borderline states on which subjects indicate those that they experience. Descriptions of possible subjective experiences, of possible relationships between self and other and of a range of other features are provided, and respondents describe each of their states in turn by underlining those descriptions that apply.The procedure (which is not a psychometric test) was completed by 17 patients with BPD. The patients identified and characterized from 4 to 10 states from the provided titles. On the basis of their face value, the descriptions of subjective experiences were classified as positive or negative and the presence of somatic or dissociative experiences was noted. Four states were described as predominantly positive and seven were described as predominantly negative; about half of the latter were accompanied by somatic or dissociative symptoms. Subjects reported harsh relationship patterns in association with the subjectively negative states. These findings are consistent with the Multiple Self States Model of BPD. This was developed as part of Cognitive Analytic Therapy theory, but it is suggested that clinicians working with other therapy models or with pharmacotherapy could find the procedure helpful in understanding and managing this difficult and often disruptive patient group. Copyright © 2007 John Wiley & Sons, Ltd.
Dysfunctional schemas and psychopathology in referred obese adolescents
Authors: Van Vlierberghe Leen , Braet Caroline 
Published: September 2007

AbstractObjective: Referred obese adolescents often display psychological problems. The present study aimed at investigating whether Young's schema theory constitutes a comprehensive framework to understand psychopathology in youth in general and in referred obese adolescents in particular. Methods: 91 youngsters referred for obesity treatment and 91 normal weight controls (all between 12 and 18 years of age) filled out the Young Schema Questionnaire and the Youth Self‐Report. Parents were asked to complete the Child Behavior Checklist. Results: The obese youngsters displayed an overall greater severity of dysfunctional schemas than normal weight controls. The obese group scored significantly higher for the schemas Emotional Deprivation, Social Isolation/Alienation, Defectiveness/Shame, Failure to Achieve, Dependence/Incompetence and Subjugation. Social Isolation/Alienation and Vulnerability to Harm/Illness were highly predictive for internalizing symptoms in youth. The schemas Entitlement and Dependence/Incompetence were predictive for externalizing symptoms in youth. Conclusion: Referred obese individuals display high levels of maladaptive schemas and these are generally related to internalizing and externalizing symptoms. Copyright © 2007 John Wiley & Sons, Ltd.
Cognitive therapy for bulimia nervosa: an A‐B replication series
Authors: Cooper Myra , Todd Gillian , Turner Hannah , Wells Adrian 
Published: September 2007

AbstractObjective: To investigate whether a new treatment for bulimia nervosa (BN) works, and to examine its effects on key cognitions and behaviours hypothesized to be important in the underlying model.Method: An A‐B single‐case series with follow‐up was conducted. Treatment was based on a specific model of BN. It consisted of individualized formulation, enhancing motivation for change, cognitive restructuring of specific cognitions, behavioural experiments and targeting particular underlying assumptions and negative self‐beliefs. Relapse prevention was also addressed.Results: All treatment completers did extremely well and no longer met Diagnostic and Statistical Manual of Mental Disorders, 4th edition revised (DSM‐IV) criteria for bulimia nervosa. Two were entirely symptom‐free at the end of treatment and at follow‐up. The third experienced only very occasional binge eating and vomiting. Individual scores on self‐report symptom measures and on all measures of cognition indicated a return to normative levels.Discussion: Treatment focusing on specific cognitive change is a promising intervention for BN. Further work might usefully evaluate this treatment in a larger study. Copyright © 2007 John Wiley & Sons, Ltd.
Assessment of borderline pathology using the Inventory of Interpersonal Problems Circumplex Scales (IIP‐C): a comparison of clinical samples
Authors: Hilsenroth Mark J. , Menaker John , Peters Eric J. , Pincus Aaron L. 
Published: September 2007

AbstractWe examined the interpersonal functioning of 74 outpatients at a university‐based community clinic in a naturalistic study. Twenty‐three individuals diagnosed with borderline pathology (BP) were compared with a non‐BP clinical control group (n = 51). Based on previous research, we hypothesized that individuals with BP would report significantly greater overall interpersonal distress as well as greater problems associated with non‐assertive, overly accommodating, self‐sacrificing and intrusive/needy relational behaviours. We found that individuals with BP reported greater interpersonal distress in regard to overly accommodating, self‐sacrificing and intrusive/needy relational behaviours. A trend was observed in regard to differences in overall interpersonal distress. Evaluation of the group‐level circumplex profiles confirmed group homogeneity in interpersonal problem endorsement, supporting the aggregate descriptions of interpersonal style as representative of individuals within each group. The clinical utility of our results, specifically in regard to psychotherapy process and outcome as well as therapeutic alliance, will be discussed. Copyright © 2007 John Wiley & Sons, Ltd.