bluuebunny/crossref_metadata_2025_split huggingface dataset:
COMPONENT COMPOSITIONS OF THE ESSENTIAL OIL AND PHENOLIC COMPOUNDS OF THE AERIAL PART OF LOPHANTHUS SCHTSCHUROVSKIANUS
Authors: Askarova Oydin Karimkhon kizi , Bobakulov Khairulla Mamadievich , Ganiev Adhamjon Askarali ugli , Usmanova Nargiza Kudratullaevna , Sasmakov Sobirjan Anarmatovich , Eshboev Farhod Bakir ugli , Ботиров Эркин Хожиакбарович , Azimova Shahnoz Sadykovna 
Published: March 2024

The component composition of the essential oil (EO) obtained by hydrodistillation from the air dried aerial part of the Lophanthus schtschurowskianus (Regel) Lipsky, growing in the Surkhandarya region of the Republic of Uzbekistan, was studied. By the GC-MS method were identified 57 components in the composition of EO, which was 93.8% of the total amount of oil, of which 52 volatile compounds were identified. The main components of the essential oil were 1,8-cineol (13.4%), viridiflorol (8.5%), α-terpineol (4.3%), terpinen-4-ol (4.2%), τ-cadinol (4.1%), β-spatulenol (3.9%), α-p-dimethylstyrene (2.1%). Oxygenated monoterpenes (33.6%) and oxygenated sesquiterpenes (24.7%) predominate in the composition of the essential oil; compounds related to sesquiterpene hydrocarbons (8.6%) were also found. The composition of the EO components of L. schtschurowskianus significantly differs from the EOs of other studied plant species of the genus Lophanthus.
The antibacterial and antifungal activity of the essential oil, as well as various extracts from the aerial parts of L. schtschurowskianus, was studied using a modified agar diffusion method. Gram-positive bacteria were found to be susceptible to all the studied samples. Among the studied samples, the essential oil showed the highest antibacterial activity against Bacillus subtilis, Staphylococcus aureus, Pseudomonas aeruginosa and Escherichia coli.
Three individual phenolic compounds were isolated from various fractions of a 75% alcoholic extract of the aerial part of L. schtschurowskianus, which, based on the study of 1H, 13C NMR, HSQC and HMBC spectra, were identified as caffeic, rosmarinic acids and luteolin.
Acute Liver Failure With Liver Enzymes >5,000 in Sickle Cell Disease
Authors: Wadhavkar Neha , Nsubuga John Paul , Ibrahim Nouran , Kumar Prasanna , Hsu Andrew , Simmons Shannon 
Published: March 2024

ABSTRACT
Sickle cell disease is a hemoglobinopathy often complicated by painful vaso-occlusive episodes, acute chest syndrome, stroke, and myocardial infarction. Sickle cell intrahepatic cholestasis (SCIC) is a rare and potentially fatal complication of sickle cell disease. SCIC is thought to involve progressive hepatic injury due to sickling within sinusoids. We present the case of a young patient with SCIC and acute liver failure, requiring prompt treatment with exchange transfusion. Our case describes features that should raise suspicion for hepatic failure in SCIC and highlights exchange transfusion as a successful management approach in similar patients with an otherwise high risk of mortality.
Novel cardioprotective and nephroprotective combination in patients with type 2 diabetes and chronic kidney disease: perspectives of use
Authors: Khalimov Yu. Sh. , Semikova G. V. , Shutova Yu. A. 
Published: March 2024

Chronic kidney disease (CKD) is a common complication of diabetes mellitus. It increases significantly cardiovascular risk and decreases the quality of life. CKD requires treatment, and the treatment paradigm for type 2 diabetes has shifted from a glucose-centric approach towards disease-modifying therapy. Attention is being paid to cardioprotective and nephroprotective effects. In patients with type 2 diabetes and CKD, drugs that affect the renin-angiotensin-aldosterone system, as well as sodium-glucose cotransporter type 2 inhibitors (iSGLT2) are widely used. Despite the proven positive effect of these drugs in preservation of renal functions, the pathogenesis of CKD contains links that have not yet been covered. In particular, the activity of fibrosis processes in the renal parenchyma is increased in patients with CKD due to high expression of mineracorticoid receptors. It may be a potential target for nephroprotective drugs. Thus, mineralocorticoid receptor antagonists (MCRA) may influence the residual risk of CKD progression. In particular, the effectiveness of the non-steroid selective AMCR finerenone has been proven in a number of large clinical studies, which confirmed its nephroprotective potential. In this regard, studies aimed at studying the joint effect of known nephroprotective drugs, as well as their combined effect on cardiovascular risk, are highly needed.This review marks the main mechanisms of the combined action of iSGLT2 and finerenone. Discussion of the results of main clinical studies with combined use of standard nephroprotective therapy, SGLT2 and finerenone is also presented.
Prevalence of heart failure among hospitalized patient with T2D: results of a prospective observational multicenter study (CREDO)
Authors: Antsiferov M. B. , Kobalava Zh. D. , Demidova T. Y. , Markova T. N. , Tolkacheva V. V. , Morgunov L. Y. , Andreeva A. V. , Pashkova Е. Y. , Khaziakhmetova M. R. , Samburova E. S. , Vedyashkina S. G. , Mkrtumyan A. M. , Petunina N. А. , Serebrov A. N. , Deeva T. M. , Karaeva A. Y. 
Published: March 2024

BACKROUND: Heart failure (HF) is in the first place in the structure of cardiovascular death in patients with type 2 diabetes mellitus (T2D). One of the factors determining the prognosis of patients with this pathology is hospitalization. The difficulties of managing patients are related to the heterogeneity of the population. In some cases, HF in patients with T2D remains undiagnosed, and data on the true frequency of HF in patients with T2D and their clinical and laboratory characteristics in real clinical practice remain limited.AIM: To assess the prevalence of HF, clinical and demographic characteristics and therapy profile in patients with T2D admitted to multidisciplinary hospitals.MATERIALS AND METHODS: A prospective observational multicenter study was conducted at the city clinical hospitals of the Moscow. For the period from August 2022 to April 2023, data from patients with T2D were analyzed. Data collection was carried out at one visit. The study design did not involve any intervention in routine clinical practice, including the choice of diagnostic method or treatment.RESULTS: The study included 445 patients in accordance with the main inclusion criteria - T2D, age over 50 years, duration of T2D more than 3 years. The incidence of HF in patients with type 2 diabetes at discharge was 76.6%. The diagnosis of HF was confirmed in 48.7% (n=217), newly diagnosed HF occurred in 27.9% (n=124) of cases, in 12.6% of patients (n=56) the diagnosis of HF was withdrawn, in 10.8% (n=48) of cases the diagnosis of HF was not established. The frequency of prescribing drugs at discharge was iSGLT-2 — 77.3% (n=344), statins — 86.7% (n= 386), MRAs — 23.1% (n=103), diure­tics — 46.1% (n=205).CONCLUSION: 76.6% of patients with T2D admitted to multidisciplinary Moscow hospitals were diagnosed with HF at discharge. The results obtained confirm the possibility of detecting HF and initiating cardioprotective therapy at the hospital stage, using inpatient clinical diagnostic examination, and patients with type 2 diabetes lasting more than 3 years and aged over 50 years can be classified as a high risk group for developing HF.
Das Markenimage von Huawei in deutschen Medien 2009–2023.
Authors: Xu Zeming , Zhan Xia 
Published: March 2024

Zusammenfassung
Der vorliegende Beitrag schließt sich dem Ansatz der linguistischen Imageanalyse (LIma) an und versucht auf der Basis eines selbst erstellten Korpus mit insgesamt 1037 Huawei-bezogenen Texten aus den deutschsprachigen Print-Medien Der Spiegel, Focus Magazin, Stern, Die Welt, Die Zeit (inkl. ZEIT Magazin) und die tageszeitung in dem zeitlichen Intervall von 2009 bis 2023, einen Einblick in die Konstruktion des Huawei-Markenimages in deutschen Medien zu vermitteln. Die Studie kommt zu dem Ergebnis, dass die deutsche Medienberichterstattung über Huawei eine Dualität von Anerkennung und Zweifel aufweist und ein komplexes ambivalentes Markenimage von Huawei konstruiert: (1) In der wirtschaftlichen Dimension erkennen die deutschen Medien die führende Technologie und fortschrittliche Produkte von Huawei und konstruieren das Image von Huawei als ein internationaler führender Hightech-Hersteller mit Entwicklungspotenzial; (2) in der politischen Dimension nehmen die deutschen Medien dauerhaft die grundlosen Vorwürfe und das Durchgreifen gegen Huawei in den Fokus, wobei sie absichtlich den chinesischen Hintergrund von Huawei hervorheben und Huawei als einen Fremden mit Gefahrenpotenzial inmitten von Kontroversen über Cybersicherheit und Compliance darstellen, was eine distanzierende Neigung der Berichterstattung signalisiert. Das ambivalente Markenimage ergibt sich sowohl aus der komplexen kollektiven Identität der Gesellschaft, in der die deutschen Medien tätig sind, als auch aus der Stärke in Technologie des Unternehmens.
Surface tension measurement of FAP-based ionic liquid pendant drops in a high vacuum/gas cell
Authors: Tiongson Julius Kim , Martinez Imee Su 
Published: March 2024

Abstract
The surface tension of ionic liquids with the tris(pentafluoroethyl)trifluorophosphate (FAP) anion were measured using a home-built surface tensiometer. A high-vacuum line was used to pre-evacuate the ionic liquids prior to analyses, ensuring that the samples were free of dissolved gases, water, and volatile impurities. Using the pendant drop method, measurements were performed in a custom-built surface tension vacuum or gas cell, in the presence of nitrogen and carbon dioxide gas. To calibrate the instrument, surface tension measurement of known liquids was also performed. Results show that the presence of saturated carbon dioxide led to the lowering of measured surface tension values, indicating the adsorption of CO2 on the ionic liquid surface.
Metabolomic and proteomic applications to exercise biomedicine
Authors: Wilkinson Daniel J. , Crossland Hannah , Atherton Philip J. 
Published: March 2024

Abstract

Objectives
‘OMICs encapsulates study of scaled data acquisition, at the levels of DNA, RNA, protein, and metabolite species. The broad objectives of OMICs in biomedical exercise research are multifarious, but commonly relate to biomarker development and understanding features of exercise adaptation in health, ageing and metabolic diseases.

Methods
This field is one of exponential technical (i.e., depth of feature coverage) and scientific (i.e., in health, metabolic conditions and ageing, multi-OMICs) progress adopting targeted and untargeted approaches.

Results
Key findings in exercise biomedicine have led to the identification of OMIC features linking to heritability or adaptive responses to exercise e.g., the forging of GWAS/proteome/metabolome links to cardiovascular fitness and metabolic health adaptations. The recent addition of stable isotope tracing to proteomics (‘dynamic proteomics’) and metabolomics (‘fluxomics’) represents the next phase of state-of-the-art in ‘OMICS.

Conclusions
These methods overcome limitations associated with point-in-time ‘OMICs and can be achieved using substrate-specific tracers or deuterium oxide (D2O), depending on the question; these methods could help identify how individual protein turnover and metabolite flux may explain exercise responses. We contend application of these methods will shed new light in translational exercise biomedicine.
Research on cascade control method for turboshaft engine with variable rotor speed
Authors: Yao WenRong , Li Wenbo , Wu JinDong , Su Chong 
Published: March 2024

Abstract
In order to realize high-quality control for turboshaft engine with variable rotor speed, a cascade control method based on the acceleration estimator of gas turbine speed (N

gdot
) through Complementary filtering – incremental nonlinear dynamic inversion (CF-INDI)with Newton’s prediction is proposed. Firstly, an adaptive torsional suppression method based on the Recursive Least Square (RLS) algorithm and combined with the control index of power turbine speed is proposed and designed to solve the torsional instability of control system in turboshaft engine with variable rotor speed. Then, an online N

gdot
estimated method based on CF-INDI with Newton’s prediction is developed, and the complementary filtering method is applied to compensate for the inaccuracy of the state variable model available at a single working point, and Newton prediction is used to alleviate the problem of lagging acceleration estimate, which is accessible to realize the cascade control for turboshaft engine based on N

gdot
. The simulation results show that the RLS adaptive torsional filter can effectively suppress the low-order torsional components with frequencies of 1.2 Hz and 2.0 Hz mixing in power turbine speed, and the torsional suppression effect is remarkable. In addition, under different flight conditions, CF-INDI with Newton prediction is faster and more accurate than INDI N

gdot
estimate, and smoother than central difference method, which proves the feasibility of INDI N

gdot
estimator. Meanwhile, after the application of CF-INDI with Newton prediction N

gdot
estimator in cascade control, the anti-interference capacity of power turbine speed is stronger, and the dynamic control effect is superior, which has satisfactory robustness performance.
Neuronal modeling of cross-sensory visual evoked magnetoencephalography responses in auditory cortex
Authors: Lankinen Kaisu , Ahveninen Jyrki , Jas Mainak , Raij Tommi , Ahlfors Seppo P. 
Published: March 2024

Previous studies have demonstrated that auditory cortex activity can be influenced by cross-sensory visual inputs. Intracortical laminar recordings in non-human primates have suggested a feedforward (FF) type profile for auditory evoked but feedback (FB) type for visual evoked activity in the auditory cortex. To test whether cross-sensory visual evoked activity in the auditory cortex is associated with FB inputs also in humans, we analyzed magnetoencephalography (MEG) responses from eight human subjects (six females) evoked by simple auditory or visual stimuli. In the estimated MEG source waveforms for auditory cortex regions of interest, auditory evoked response showed peaks at 37 and 90 ms and visual evoked response at 125 ms. The inputs to the auditory cortex were modeled through FF- and FB-type connections targeting different cortical layers using the Human Neocortical Neurosolver (HNN), which links cellular- and circuit-level mechanisms to MEG signals. HNN modeling suggested that the experimentally observed auditory response could be explained by an FF input followed by an FB input, whereas the cross-sensory visual response could be adequately explained by just an FB input. Thus, the combined MEG and HNN results support the hypothesis that cross-sensory visual input in the auditory cortex is of FB type. The results also illustrate how the dynamic patterns of the estimated MEG source activity can provide information about the characteristics of the input into a cortical area in terms of the hierarchical organization among areas.Significance statementLaminar intracortical profiles characterize feedforward- and feedback-type inputs to a cortical area. By combining magnetoencephalography (MEG) and biophysical computational neural modeling, we obtained evidence of cross-sensory visual evoked activity in the human auditory cortex driven by feedback-type input. The finding is consistent with previous intracortical recordings in non-human primates. The results illustrate how patterns of MEG source activity can be interpreted in the context of the hierarchical organization among cortical areas.
APAKAH JOGGING 2 KILOMETER BERPENGARUH TERHADAP KELENTURAN
Authors: Wansah Syahbayu Dinda , Samodra Touvan Juni , Yosika Ghana Firsta , Gandasari Maharani Fatima , Sastaman B Putra Sastaman 
Published: March 2024

Abstrak

Tujuan dilakukannya penelitian ini untuk mengetahui pengaruh jogging 2km terhadap kelenturan. Metode yang di gunakan pada penelitian ini adalah eksperimen dengan menggunakan Desain One Group Pretest – Post Design. Sampel yang digunakan pada penelitian ini diperoleh dari mahasiswa Prodi Pendidikan Kepelatihan Olahraga semester satu berjumlah 22 orang yang secara sukarela berpartisipasi dalam penelitian. Penelitian ini menggunakan pengetesan sit and reach sebelum dan sesudah melakukan jogging 2km. Teknik analisis data menggunakan deskriptif dan Uji t. Hasil penelitian menunjukkan bahwa adanya perbedaan kelenturan sebelum melakukan jogging sebesar 11,09 cm, setelah melakukan jogging 2km sebesar 13,44 cm, dengan demikian melakukan jogging 2km juga sangat efektif digunakan untuk mengolah tubuh menjadi lentur

Abstract

The study aimed to determine the effect of jogging for 2km on flexibility. The method used in this research is an experiment using the One Group Pretest – Post Design. The sample used in this study was students in the first semester of the Sports Coaching Education Study Program, totaling 22 students, who voluntarily participated in the research. This Study used sit-and-reach testing before and after jogging 2km—data analysis techniques using descriptive and t-tests. The results showed a difference in flexibility before jogging of 11.09 cm and after jogging 2km of 13.44 cm. Thus, jogging for 2km is also very effective in making the body more flexible.
IDENTIFIKASI PERSONALITY ATLET SELAM KOTA SEMARANG MELALUI MYERS-BRIGGS TYPE INDICATOR
Authors: Sungkowo Sungkowo , Candra Adiska Rani Ditya , Margono Margono , Priyanto Priyanto , Ulinnuha Rizam Ahada Nur , Wijayanti Febriana Wahyu 
Published: March 2024

Tujuan penelitian ini adalah untuk mengetahui personality atau karakteristik atlet selam, Karakteristik atlet yang dimaksud adalah karakter pribadi individu yang khas dari masing-masing atlet pada suasana tingkah laku yang ditandai oleh pengaruh negatif dan gejala ketegangan jasmani. Metode menggunakan deskriptif kuantitaif dengan pengumpulan data menggunakan test MBTI (myers briggs type indicator ). Hasil penelitian menunjukkan bahwa personality tiap atlet berbeda beda hasilnya. kategory ESTJ ada 3 atlet, sedangkan kategori lain masing-masing berjumlah 1 atlet yakni: ESKP, ESTP, ENTP, ISFP serta dua atlet lainnya memiliki kategori ISTJ. Atlet yang mempunyai sikap mudah beradaptasi dengan lingkungan ada 6 atlet, sedangkan dengan sikap tertutup, kurang bersosial dengan dengan teman sekitar atau berkarakter introvet ada 3 atlet. Simpulan dalam penelitian mengindikasikan bahwa para atlet harus mengetahui kepribadian nya dan pelatih di harapakan dapat memberikan solusi yang baik jika atlet mempunyai sikap kepribadian yang kurang baik, kurang berdaptasi/bersosial.
PENGARUH LATIHAN LARI 20 METER DAN LATIHAN LARI ZIG-ZAG TERHADAP KECEPATAN MENGGIRING BOLA
Authors: Islamabad Oki , Syafaruddin Syafaruddin , Bayu Wahyu Indra , Victorian Ahmad Richard 
Published: March 2024

Penelitian ini bermaksud untuk mencari tahu pengaruh lari 20-meter dan latihan lari zigzag sambil meningkatkan kecepatan menggiring bola pada ekstrakurikuler sepak bola SMPNegeri 1 Tanjung Batu. Pada saat melakukan teknik ini pemain masih terlihat kurang menguasai dengan benar sehingga pergerakannya lamban dan terlihat kaku sehingga memungkinkan bola direbut dengan mudah. Total sampling diterapkan pada peneltitina ini dengan jumlah 30 peserta didik yang mengikuti ekstrakurikuler sepak bola. Metode yang diterapkan adalah eksperimen semu dengan desain one group pretest-posttest dan menggunakan tes kecepatan dalam menggiring bola untuk memperoleh data penelitian. Setelah diberikan perlakuan berupa latihan lari sprint 20 meter dan latihan lari zigzag tiga kali dalam seminggu dalam waktu enam minggu dengan intensitas latihan 80-90%. Berdasarkan uji paired sample test. Berdasarkan tabel tersebut, nilai signifikasi sebesar 0,000 dengan nilai t hitung sebesar 17,545 dan ttabel sebesar 1,699. Oleh karena nilai signifikansi lebih kecil dari pada 0,05 (0,000<0,05) dan nilai thitung>ttabel (17,545>1,699), maka hasil tersebut menunjukkan bahwa adanya perbedaan yang signifikan didapatkan bahwa tersebut, yang artinya bahwa ada hubungan signifikan latihan lari sprint 20 meter dan Latihan lari zigzag terhadap kecepatan menggiring bola.
Legal Status of the State Language in Lithuania after the Restoration of Independence
Authors: Žemaitis Dainius , Valotka Audrius 
Published: March 2024

The Constitution of the Republic of Lithuania has established the highest official status of a language, i.e. a state language. Compliance with this status requires an appropriate legal framework and institutions that develop and enforce language policy and legislation.
The article reviews the development of the status of the Lithuanian language from 1918 to the present day, and presents the institutions that supervise the use and correctness of the language.
The article describes the legal regulation of the official language in Lithuania. It reviews the legal acts that establish the requirements for the correctness and use of the language, and presents a hierarchical system of the related legal acts. The institutions responsible for language policy and protection are described.
Dialectology at Vilnius University
Authors: Judžentytė-Šinkūnienė Gintarė , Kardelis Vytautas 
Published: March 2024

The paper aims to review the history of dialectology at Vilnius University since the establishment of the Department of the Lithuanian Language in 1940. To achieve this, we have set the following objectives: 1) to present the teaching of dialectology, 2) to review the dialect material collection, and 3) to examine existing research. Descriptive, analytical, and evaluative methods are applied in the study.
The beginning of dialectological research is associated with the name of Antanas Salys. The works of Aleksas Girdenis and Zigmas Zinkevičius are also discussed in the paper, as well as the teaching of the dialectology subject, methods of collecting dialectological material and directions of dialectological research. The paper distinguishes the paradigms of traditional, structural, and new dialectology dialectology, and examines their methodological similarities and differences.
The most important conclusions and summaries of the paper are fundamentally related to dialectological paradigms: in more than eighty years since the first dialectology subject taught at Vilnius University, the understanding of dialectology has changed. The stage of traditional dialectology at the University was extremely important, as it produced the most fundamental works that are still used today. The structural dialectology paradigm and Prof. Girdenis Dialectology School that trained a large group of productively working Lithuanian dialectologists has flourished over the years. Currently, the new paradigm of dialectology is making its way, offering new theoretical and methodological approaches to the study of dialects.