bluuebunny/crossref_metadata_2025_split huggingface dataset:
COMPARATIVE STUDY OF POLYPHENOLIC COMPOSITION AND REDUCING PROPERTIES OF EXTRACTS OF CANNABIS SATIVA L., CANNABIS INDICA AND CANNABIS HYBRID
Authors: Vetskov Nikolay , Kaloyanov Nikolay , Hinkov Ivaylo , Diankov Svetlomir , Pashova Katya , Gerasimova Vanya , Funeva-Peycheva Milena , Yankovska-Stefanova Todorka , Garbev Atanas 
Published: March 2024

Cannabis Sativa L., Cannabis Indica and Cannabis Hybrid are widespread plant species that find legal use in many countries around the world. The first of them has found considerable application in medicine, cosmetics, building construction, textile and food industries. Cannabis Indica and Cannabis Hybrid are used as raw materials for the extraction of oils that are used as pain relievers as well as for recreation purposes. The aim of the present study is to compare the polyphenolic composition of extracts from the three types of plants, by the maceration method of dry green leaf mass consisting of inflorescences and leaves. Ethanol (99.9 %) is used as an extractant, and the duration of the maceration process is seven days, at room temperature and stirring. The polyphenol composition is determined using HPLC-DAD method.
The following polyphenol composition is found in extracts of Cannabis Sativa L.: epigallocatechin, rutin, myricetin, quercetin and kaempferol. On the other hand, quercetin and kaempferol are detected in the Cannabis Indica samples, while epigallocatechin, quercetin and kaempferol are present in the hybrid sort. In addition, green synthesis of silver nanoparticles by using sunlight or microwave irradiation was carried out to evaluate the reduction properties of three cannabis extracts. The least quantity of silver nanoparticles was obtained in the presence of Cannabis Sativa L. extracts. From the other two species of cannabis, microwave irradiation produces more silver nanoparticles, with smaller sizes, while exposure to direct sunlight produces fewer particles,but with larger sizes.
EFFECTS OF ZEOLITE INCORPORATION AND INERT FILLERS ON THE CURING OF CEMENT MORTARS
Authors: Petkova Vilma , Stoyanov Ventseslav , Kostova Bilyana , Mihaylova Katerina 
Published: March 2024

One of the main approaches to reducing the environmental impacts of the construction industry is the use of mineral additives reducing the use of cement in mortars and concretes for construction. The objects of this research are different cement composites with high content of inert mineral fillers (marble and quartz sand), the influence of zeolite incorporation on the microstructure, and low water-cement ratio, obtained after the hydration of white portland cement.In this study, the evolution of the curing processes and the crystal formation during up to 120 days of water-curing are investigated. Moreover, the effects of replacing up to 10 wt. % of white cement with natural zeolite are studied. Attention was focused on the general microstructural development during curing with special attention on the evolution and morphology of pore space and the observed calcium silicate hydrates (C–S–H), portlandite, and carbonate-containing phases.The phase composition (newly formed phases as well as the formation of C-S-H gel) is defined by using powder X-Ray diffraction and SEM. The experimental data shows that the cement composites with the inert marble filler as an additive lead to the creation of carbo-aluminates. The incorporation of up to 10 percent of clinoptilolite in concrete mixtures by mass of the total cementitious components is more efficient when used in lower strength mixes. A significant reduction in the workability of the fresh mortars is not observed, but the high surface area of zeolite reduces bleeding and accelerates setting without any strong effects on the other physical and technological properties of fresh mortars.
Usaha Bioflok Dalam Upaya Meningkatkan Ketahanan Pangan Di Desa Modelomo Kecamatan Tilamuta Kabupaten Boalemo
Authors: Tohopi Rustam , Nani Yacob Noho 
Published: March 2024

Pengabdian ini didasarkan pada hasil observasi awal dengan pemerintah desa dan masyarakat terkait permasalahan yang dihadapi di desa Modelomo Kecamatan Tilamuta Kabupaten Boalemo. Berbagai permasalahan yang terungkap banyaknya masyarakat pedagang namun belum dimanfaatkan/diberdayakan melalui usaha bioflok; Belum ada yang menggeluti usaha bioflok ikan lele di desa Modelomo. Upaya salah satu yang diprioritaskan adalah membentuk usaha kelompok bioflok di desa Modelomo. Program KKN Terintegrasi MBKM ini bertujuan untuk mendorong terbentuknya usaha kelompok baru bioflok ikan lele sebagai sarana pengembangan usaha pada masa yang akan datang dalam meningkatkan ketahanan pangan di desa Modelomo melalui pemberdayaan masyarakat. Metode yang digunakan dalam KKN terintegrasi MBKM ini yakni membentuk usaha dan melakukan pelatihan dan proses pendampingan program dengan model pemberdayaan masyarakat kelompok usaha bioflog di desa Modelomo. Dengan pelatihan dan pendampingan ini kelompok usaha bioflok ikan lele dapat terbentuk dan memahami secara seksama tata cara budidaya dan pengembangan potensi dan keberlanjutan usaha untuk ketahanan pangan desa sekaligus pemenuhan kebutuhan ekonomi keluarga. Dari pengabdian ini hal terpenting adalah motivasi tinggi dari masyarakat desa dalam menggeluti usaha sangat baik, hal ini dapat dibuktikan dengan dukungan biaya dana desa dari pemerintah desa yang akan dialokasikan untuk jenis pemberdayaan masyarakat pada dusun-dusun yang belum terbentuk usahanya, dengan mengupayakan kelompok-kelompok usaha baru yang berbeda dengan yang sudah berjalan. Hal inilah sebagai upaya meningkatkan kompetisi usaha yang sehat dan untuk menghindari kompetisi usaha yang menimbulkan kebosanan dalam mengelola bidang usaha
Pelatihan Pengolahan Data Penelitian: Estimasi Parameter dan Analisa Regresi Menggunakan R Untuk Guru SMA Di Jakarta dan Sekitarnya
Authors: Riyono Joko , Pujiastuti Christina Eni , Syaifudin - - , Puspa Sofia Debi 
Published: March 2024

Kompetensi Pengolahan Data Penelitian sangat diperlukan oleh pendidik terkait dengan kewajiban dalam penulisan naskah ilmiah sebagai prasyarat kenaikan pangkat. Guru sebagai ujung tombak kemajuan pendidikan di Indonesia diharapkan mempunyai pengetahuan yang bagus dalam pengolahan data penelitian guna menambah kemampuan dalam melukakan kegiatan penelitian tindakan.Â Bahasa RÂ Â merupakan perangkat lunak terpadu open source yang dapat digunakan untuk manipulasi data, kalkulasi, simulasi dan peragaan grafik. Dalam rangka memberikan tambahan pengetahuan pengolahan data penelitian memanfaatkan open source R kepada para GuruÂ Sekolah Menengah Atas di wilayah Jakarta dan sekitarnya maka progam Pengabdian Kepada Masyarakat ini diberikan kepada mereka. Penyampaian materi dalam pelatihan ini dilakukan secara daringÂ menggunakan Zoom Meeting diikuti dengan sesi diskusi dan tanya jawab. BerdasarkanÂ hasil pre test dan post testÂ para peserta, terlihat kenaikan pengetahuan peserta dalam pemahaman pemakaian Bahasa R untuk pengolahan data penelitian dari skor nilai 3.095 menjadi 6,782. Guna mengetahui pendapat peserta mengenai manfaat yang diperoleh dengan mengikuti pelatihan PKM maka diakhir pelatihan para peserta diminta mengisi kuesioner,diperolehÂ Nilai Indeks skala Likert 88,122% yang mengisyaratkan bahwasannya pelaksanaan pelatihan baik mengenai materi dan cara penyampaiannya dirasa sangat dapat diikuti oleh mitra.
Learners’ Interests, Attitudes, and Compliance to Modular Distance Learning During Pandemic
Authors: Pasa Theresa , Alfonso Alvin 
Published: March 2024

Students and teachers no longer engage in face-to-face instruction; instead, they follow the Basic Education Learning Continuity Plan (BE – LCP). The majority of schools have adopted the Modular Distance Learning modality, which allows students to study at their own pace. Thus, this study looks into the compliance, interests, and attitudes of 100 Senior High students who participated in modular remote learning. A survey and deductive topic analysis were used as research tools. In order to gather information about their study habits, interest, attitudes, and compliance with the learning modules, they were requested to complete an original survey questionnaire. The study's conclusions demonstrated that the modules' lessons' comprehension, complexity, and presentation all work to maintain respondents' attention. The learners' environment and parental support allow them to keep a positive outlook throughout the process. The students complied with requirements, completing assignments with less oversight and even forgoing sleep when necessary to do some assignments right away. The findings showed that rather than whining, students always tried their hardest to complete their assignments. This required them to adapt to a completely different style of learning. Every student is a unique individual with unique skills and interests, and our goal is to support each learner's independence and ability to think for themselves. This keeps parents informed about their children's endeavors and can offer resources, support, and encouragement. The government may help students by stepping up and virtualizing already-existing programs, as well as by enlisting the help of other organizations to organize joint activities that will enhance the current mode. This study is crucial because it will act as a foundation for future enhancements to the current curricula at the schools and policies on the use of modular distant learning.
Academic Related Values-Oriented Skills Demonstrated During Pandemic
Authors: Bermudes Sharon , Pagsuguiron Jayvee 
Published: March 2024

Values are an individual's conventions that serve as a guide for deciding what is right and wrong. It either comes naturally to a person or is gained over time through interactions with family, community, and society. However, the COVID-19 epidemic has recently hindered human connections, disrupted sociability and gatherings, and may have had a significant impact on people's conduct in general and on schoolchildren in particular. The teaching of academic and values-based skills in schools might be discontinued, which would probably hinder the growth of a developing child whose overall wellbeing is somewhat dependent on our educational system. The Department of Education made sure that children wouldn't be significantly impacted by the COVID-19 pandemic in light of its impacts. The study looks into the values-oriented academic skills that junior high school students displayed during the epidemic. The replies from the sixty junior high school respondents were totaled in order to ascertain the academically connected, values-oriented capabilities of the learners during the epidemic. The results indicated that, in spite of distance learning, students continued to exhibit values-oriented skills, which is crucial to their overall development. The result's implication implies that, despite the COVID-19 epidemic, it is still necessary to uphold and promote other values-oriented abilities in the teaching and learning process.
Does Female Board Presence Moderate on the Relationship between Board Characteristic and Capital Structure? Evidence from Nigeria Listed Firms
Authors: Chukwunwike Onyekachi David , Okobo Mirian Mukosolu , Nnam Imaobong Judith 
Published: March 2024

The study examines how female board presence moderates the relationship between corporate governance and capital structure of non-finance companies listed in Nigeria. The study covers a period of ten years from 2012 to 2021 using data obtained from Machame ratios database. A sample size of sixty non-finance listed firms were used. Using Stata version 14, he OLS pooled regression, diagnostic and robustness tests are carried out. result shows that larger board size of big and small non-finance firms in Nigeria tend to reduce their capital structure. Similarly, independence of the board of directors of big non-finance firms in Nigeria tend to reduce their capital structure. However, the board independence of smaller non-finance firms tends to increase their debt to asset ratio insignificantly. Again, the outcome shows that having a female director on a large board significantly decreases the level of leverage of the smaller firms in the sample. The study also shows that having a female director on an independent board significantly increases the debt-to-asset ratio of the bigger firms in the sample. The study recommends at least one female director on a large board, increase in firms share capital and a review of the policies on female board members.
Characterization of the conformational changes of partially hydrolyzed polyacrylamide chains in solution using stress recovery experiment
Authors: Zhao F. , Du Yu K. , Liu Shu F. , Xu Jing K. , Tang Ji A. 
Published: May 2006

AbstractIn this study, a simple empirical decay function model is fitted to the experimental data to characterize the conformational changes of partially hydrolyzed polyacrylamide (HPAM) in semidilute solutions, using the stress recovery experiment after cessation of a steady shear flow processing. With the increase of HPAM concentration and NaCl concentration, the parameter κ decreases, and this is in excellent agreement with the conformational changes of HPAM molecule chains. Experimental results show that the parameter κ can provide some information on the changes of the polymer chain conformation. the polymer chain conformation. © 2006 Wiley Periodicals, Inc. J Appl Polym Sci 101: 2709–2713, 2006
Screening and chromatographic assessing of a novel IgG biomimetic ligand
Authors: Feng Hongqin , Jia Lingyun , Li Honglin , Wang Xicheng 
Published: May 2006

AbstractA novel biomimetic ligand, N‐benzyloxycarbonyl‐l‐tyrosine (N‐cbz‐l‐Tyr), was screened by a combination method of molecular docking and immobilized receptor technique. Then, N‐cbz‐l‐Tyr was immobilized on Sepharose CL‐4B to prepare a specific affinity adsorbent for immunoglobulin G (IgG). Scatchard analysis of the binding isotherm for IgG on the adsorbent gave an association constant (Ka) of 4.91 × 106 m−1 and a theoretical maximum adsorption capacity of 17.3 mg IgG/mL gel. IgG with a purity of 98% was separated from human plasma by this new affinity adsorbent. Copyright © 2006 John Wiley & Sons, Ltd.
Determination of human plasma protein binding of baicalin by ultrafiltration and high‐performance liquid chromatography
Authors: Tang Yihong , Zhu Haiyan , Zhang Yuanyuan , Huang Chenggang 
Published: May 2006

AbstractA simple and selective HPLC assay was developed and utilized for determination of human plasma protein binding of baicalin. The method involved solid‐phase extraction and reversed‐phase chromatographic separation with a mobile phase of acetonitrile−0.02 mol/L phosphate buffer (pH 2.5; 25:75, v/v) and UV detection at 276 nm. The standard curve for baicalin was linear over the concentration range 0.1–20 µg/mL and the limit of detection was 0.02 µg/mL. The absolute recovery was greater than 76%. The intra‐day and inter‐day variations were less than 10%. Ultrafiltration technique was applied to determining the plasma protein binding of baicalin in human plasma. Results show the plasma protein binding of baicalin was in the range 86–92% over all the concentrations studied and the protein binding association constant was determined to be 1.21 × 105 L/mol at 4°C. Copyright © 2006 John Wiley & Sons, Ltd.
Mononuclear cell infiltration in clear‐cell renal cell carcinoma independently predicts patient survival
Authors: Webster W. Scott , Lohse Christine M. , Thompson R. Houston , Dong Haidong , Frigola Xavier , Dicks Demetrius L. , Sengupta Shomik , Frank Igor , Leibovich Bradley C. , Blute Michael L. , Cheville John C. , Kwon Eugene D. 
Published: May 2006

AbstractBACKGROUNDThe impact of mononuclear cell infiltration on renal cell carcinoma (RCC) biology has been controversial, previously reported to be associated with either a favorable or unfavorable prognosis. The objective of the current study was to evaluate associations between mononuclear cell infiltration in routinely prepared paraffin‐embedded specimens with survival in patients with clear‐cell RCC.METHODSA total of 306 patients were identified treated with nephrectomy for clear‐cell RCC between 1990 and 1994. A single urologic pathologist, blinded to patient outcome, reviewed the specimens and quantified the extent of mononuclear cell infiltration as absent, focal, moderate, or marked. Cancer‐specific survival was estimated using the Kaplan–Meier method. Associations of mononuclear cell infiltration with death from RCC were assessed using Cox proportional hazards regression models.RESULTSAt last follow‐up, 173 of the 306 patients studied had died, including 96 patients who died from RCC. Mononuclear cell infiltration was absent in 165 (54%), focal in 70 (23%), moderate in 53 (17%), and marked in 18 (6%). Univariately, patients with specimens that had mononuclear cell infiltration were over 2 times more likely to die from RCC compared with patients whose specimens exhibited no mononuclear cell infiltration (risk ratio, 2.63; P<.001). After adjusting for the Mayo Clinic SSIGN (stage, size, grade, and necrosis) score, patients with specimens that had mononuclear cell infiltration exhibited a significantly increased likelihood of dying from RCC compared with patients whose specimens had no mononuclear cell infiltration (risk ratio, 1.61; P = .028).CONCLUSIONSMononuclear cell infiltration is associated with death from RCC even after multivariate adjustment. Routine documentation of mononuclear cell infiltration is recommended during the pathologic assessment of RCC. Cancer 2006. © 2006 American Cancer Society.
Impact of fellowship training on pathologic outcomes and complication rates of radical prostatectomy
Authors: Rosser Charles J. , Kamat Ashish M. , Pendleton John , Robinson Tracy L. , Pisters Louis L. , Swanson David A. , Babaian Richard J. 
Published: May 2006

AbstractBACKGROUNDThe study was conducted to assess the results of radical prostatectomy (RP) performed by fellowship‐trained surgeons in the first year of independent practice.METHODSA prospective cohort study of 66 men who underwent RP performed by 2 recently graduated fellowship‐trained surgeons (C.J.R., n = 27; A.M.K., n = 39) in their first year of independent practice was undertaken. Preoperative, operative, and postoperative data were collected and analyzed. Median follow‐up of the cohort is 12.5 months.RESULTSThe median patient age was 61.2 ± 6.9 years (range, 44–74 years), the median prostate‐specific antigen level was 5 ng/mL (range, 1.2–39.4 ng/mL), and the median prostate biopsy‐determined Gleason score was 7. Of the 66 men, 25 (38%) underwent a bilateral nerve‐sparing RP, 20 (30%) underwent a unilateral nerve‐sparing RP, and 21 (32%) underwent a nonnerve‐sparing procedure. Forty‐two men (63%) underwent a pelvic lymph node dissection. The median operative time was 201 minutes. Median estimated blood loss was 734 mL (range, 300–1600 mL). There were 4 major complications—a pulmonary embolism in 3 patients and an intraoperative rectal injury in 1. Pathologic classification was as follows: pT2, 74%; pT3a, 23%; pT3b, 2%; and pN+, 2%. The positive margin rate was 14% overall and only 2% in men with pT2 disease.CONCLUSIONSResults of RP performed by fellowship‐trained surgeons in their first year of practice compare favorably with results of RP in a large series reported by more experienced surgeons. Being trained in an environment where an experienced surgeon serves as first assistant to the trainee appears to abbreviate the learning curve associated with this procedure. Cancer 2006. © 2006 American Cancer Society.
Surface‐enhanced laser desorption/ionization time‐of‐flight mass spectrometry serum protein profiling to identify nasopharyngeal carcinoma
Authors: Wing Yuen Ho David , Fan Yang Zhen , Yee‐Hang Wong Birgitta , Lai‐Wan Kwong Dora , Shun‐Tong Sham Jonathan , Ignace Wei William , Po Wing Yuen Anthony 
Published: May 2006

AbstractBACKGROUNDDiagnosis of nasopharyngeal carcinoma (NPC) at an early disease stage is important for successful treatment and improving the outcome of patients. The use of serum protein profiles and a classification tree algorithm were explored to distinguish NPC from noncancer.METHODSSerum samples were applied to metal affinity protein chips to generate mass spectra by surface‐enhanced laser desorption/ionization time‐of‐flight mass spectrometry (SELDI‐TOF‐MS). Protein peak identification and clustering were performed using the Biomarker Wizard software. Proteomic spectra of serum samples from 50 NPC patients and 54 noncancer controls were used as a training set and a classification tree with 6 distinct protein masses was generated by using Biomarker Pattern software. The validity of the classification tree was then challenged with a blind test set including another 20 NPC patients and 25 noncancer controls.RESULTSThe software identified an average of 93 mass peaks/spectrum and 6 of the identified peaks were used to construct the classification tree. The classification tree correctly determined 83% (123 of 149) of the test samples with 83% (58 of 70) of the NPC samples and 82% (65 of 79) of the noncancer samples. In a combination of the serum protein profiles with Epstein–Barr (EBV) nuclear antigen 1 (EBNA1 IgA) test, the diagnostic sensitivity and specificity were increased to 99% and 96%, respectively.CONCLUSIONSThe results suggest that SELDI‐TOF‐MS serum protein profiles could discriminate NPC from noncancer. The combination of serum protein profiles with an EBV antibody serology test could further improve the accuracy of NPC screening. Cancer 2006. © 2006 American Cancer Society.
The model for end‐stage liver disease‐based Japan Integrated Scoring system may have a better predictive ability for patients with hepatocellular carcinoma undergoing locoregional therapy
Authors: Huo Teh‐Ia , Lin Han‐Chieh , Huang Yi‐Hsiang , Wu Jaw‐Ching , Chiang Jen‐Huei , Lee Pui‐Ching , Lee Shou‐Dong 
Published: May 2006

AbstractBACKGROUNDThe Japan Integrated Scoring (JIS) system was revealed as a better model for outcome prediction compared with the Cancer of Liver Italian Program system for hepatocellular carcinoma (HCC), and the Model for End‐Stage Liver Disease (MELD) was better as a prognostic predictor for patients with cirrhosis compared with the Child–Turcotte–Pugh (CTP) system, which is a parameter used in the JIS system. The objective of the current study was to investigate the performance of the modified MELD‐based JIS system.METHODSIn the modified JIS system, the CTP class in the original JIS was replaced with MELD cut‐off scores of <10, 10 to 14, and >14. The modified JIS system was compared with the original system in 276 patients with HCC who underwent locoregional therapy (transarterial chemoembolization or percutaneous injection).RESULTSThe mean ± standard error original JIS score was 1.8 ± 1.0 (range, 0‐4), compared with 2.0 ± 1.1 (range, 0‐5) for the modified JIS system (P<.001). Using mortality as the endpoint, the area under receiver operating characteristic curve (AUC) for the modified JIS system was 0.804 compared with 0.741 for the original JIS system (P = .008) at 12 months, and the AUC was 0.853 and 0.765, respectively (P<.001), at 24 months. Survival analysis showed that the modified JIS system had a better discriminatory ability for patients in different score groups and was more accurate for outcome prediction in the Cox multivariate model.CONCLUSIONSThe current results indicated that the MELD‐based, modified JIS system has improved predictive ability compared with the original system and is a more feasible model for clinical staging in patients with HCC who are undergoing locoregional therapy. Cancer 2006. © 2006 American Cancer Society.