bluuebunny/crossref_metadata_2025_split huggingface dataset:
EXHALED NITRIC OXIDE AND AEROALLERGEN SENSITIZATION IN ASTHMATIC CHILDREN
Authors: Živanović Snežana , Šaranac Ljiljana , Bjelaković Bojko , Petrović Slobodanka , Živković Zorica 
Published: March 2024

Introduction: The examination of nitric oxide in exhaled air concentration in children suffering from asthma and to establish the relation with the degree of sensitization to aeroallergens.
Material and Methods: The examination included fifty-two children (aged 12.40 ± 2.35 years), twenty-eight male (53.85%) and twenty-four female (46.15%), with the average length of suffering from asthma 8.33 ± 3.93 years. The degree of sensitization to aeroallergens was determined by skin prick testing and assessed using the atopic index (AI).
Results: The average value of FeNO in exhaled air of children suffering from stable allergic asthma was 43.92 ± 35.63 ppb, and after a four week anti-inflammatory treatment it decreased to 34.92 ± 32.04 ppb (p<0.05). In relation to AI, the level of FeNO in exaled air was 41.00 vs. 40.69 vs 50.88 ppb, in the given order without statistically significant difference. The highest values of FeNO in exhaled air were present in children suffering from a mixed type of sensitisation, 56.85 ppb (Me 48.50) in comparison to sensitisation to seasonal allergens 15.29 ppb (Me 12) and indoor allergens 32.22 ppb (Me 26). Allergic rhinitis, the duration of asthma and the gender were not significantly related to the values of FeNO in exhaled breath, while significant was the negative correlation between the body mass index and FeNO, r = -0,43 (p˂0.01).
Conclusion: Children suffering from allergic asthma possess increased values of nitric oxide in exhaled air, which is a useful indicator of daily dosage adjustment in patients treated with anti-inflammatory drugs
UPOTREBA CIGARETA I ALKOHOLA U POPULACIJI UČENIKA OSNOVNE ŠKOLE
Authors: Milošević Jasmina , Todorović Jasmina 
Published: March 2024

Uvod: U populaciji adolescenata utvrđeni su visoka prevalencija upotrebe cigareta i alkohola i trend snižavanja uzrasne granice na kojoj mladi počinju sa njihovim konzumiranjem. Razvojni stadijum adolescencije smatra se najkritičnijim periodom za eksperimentisanje i upotrebu ovih psihoaktivnih supstanci. Za kreiranje adektvatnih preventivnih programa, usmerenih na smanjenje i sprečavanje upotrebe cigareta i alkohola, neophodno je utvrditi rasprostranjenost i obrasce konzumiranja ovih supstanci kod adolescenata.
Metodologija: Realizovana su dva istraživanja, od kojih je prvo bilo usmereno na ispitivanje učestalosti upotrebe cigareta, a drugo na ispitivanje učestalosti upotrebe alkohola. Oba istraživanja su sprovedena na teritoriji grada Beograda, na uzorku učenika starijih razreda osnovne škole, oba pola.
Rezultati: Cigarete je probala jedna trećina ispitanika (32%), među kojima je svakodnevno pušenje, u trajanju od 30 dana bez prekida, zabeleženo je kod 5,2% ispitanika. Trenutno cigarete koristi 9,5% ispitanih učenika. Skoro 80% ispitanika probalo je alkohol, od kojih jedna četvrtina pije 3 i više alkoholnih pića zaredom (26,7%) i prijavila je iskustvo pijanstva (24,3%).
Zaključak: Glavni zaključak ovog istraživanja jeste da je prevalencija upotrebe cigareta i alkohola među učenicima starijih razreda osnovne škole visoka.
SEKSUALNO PONAŠANJE I UTICAJ NA REPRODUKTIVNO ZDRAVLJE ADOLESCENATA NA TERITORIJI OPŠTINE INĐIJA
Authors: Rožek Mitrović Tanja , Petrović Vesna , Višnjevac Danilo 
Published: March 2024

Uvod: Reproduktivno zdravlje adolescenata je osetljivo na nepovoljni uticaj spoljašnje sredine, jer je uslovljeno vulnerabilnim biološkim i psihosocijalnim razvojem. Odgovornost mladih prema sopstvenom zdravlju često je nedovoljna, a ponašanje u sferi seksualnosti rizično.
Cilj rada:Cilj rada je ispitivanje seksualnog ponašanja i navika adolescenata iz opštine Inđija i njihov uticaj na reproduktivno zdravlje.
Metode rada: Ispitivanje je sprovedeno kao studija preseka tokom školske 2014.-2015.godine, među adolescentima u Inđiji, uzrasta od 15 do 19 godina. Podaci o seksualnom ponašanju adolescenata su prikupljeni anonimnim anketiranjem.
Rezultati: U istraživanju je učestvovalo 490 adolescenata, od toga 207 devojaka (42,24 %) i 283 mladića (57,75 %). Seksualne odnose je imalo 31,22% adolescenata, i to 39,57 % mladića i 19,80 % devojaka. Mediana uzrasta stupanja u prvi seksualni odnos za adolescente je 16,33 godine, pri čemu 16,25 godina za mladiće i 16,53 godina za devojke.Svega 13,26% adolescenata koji su seksualno aktivni su imali neki vid edukacije o reproduktivnom zdravlju. Adolescenti roditelja sa nižom stručnom spremom stupaju u ranijem uzrastu u prvi seksualni odnos. Od kontraceptivnih sredstava adolescenti najviše koriste kondom (65,24%), ritam plodnih/neplodnih dana koriste 18,64% devojaka a 7% devojaka i partnerke ispitivanih mladića koriste antibebi pilule. Bez kontracepcije seksualne odnose ima 14,84% mladića i 8,47% devojaka. Trudnoću je imalo 2,43% od ispitivanih devojaka, a niti jedan namerni prekid trudnoće. Polnoprenosivu infekciju je imalo 1,78% devojaka i 4,87% mladića.
Zaključak: Obzirom na porast seksualno aktivnih adolescenata i sve ranije stupanje adolescenata u seksualnu aktivnost, da bi sačuvali svoje reproduktivno zdravlje adolescenti moraju biti uključeni u edukaciju o seksualnosti i planiranju porodice u ranoj adolescenciji počevši od strane roditelja, prosvetnih i zdravstvenih radnika kao i od vršnjačkih edukatora.
BRONCHOPULMONARY DYSPLASIA: TREATMENT AND PREVENTION
Authors: Cerović Sofija , Živković Zorica , Veković Vesna , Veković Borko 
Published: March 2024

Since 1967, when it was first defined and described the nature and definition of bronchopulmonary dysplasia (BPD) has evolved. Based on clinical and radiographic evidence of pulmonary disease in moderately to late premature infants with a history of respiratory distress syndrome, BPD was familiarly defined as a chronic form of lung disease in neonates treated with oxygen and positive pressure ventilation for a primary lung disorder, the nature of BPD has evolved into a “new” form of BPD typically seen in neonates surviving at the threshold of viability and characterized primarily by arrest of alveolar and vascular development. Infants develop BPD in about 1.5% of all newborn births. The incidence of BPD appears to be growing in conjunction with the increased survival of very-low-birth-weight infants who are treated for and recover from respiratory distress syndrome (RDS). This review has been an up-date of literature data, including animal studies, human pilot studies, randomized controlled trials (RCTs), meta-analyses and systematic reviews published on the PubMed data base.
DISFUNKCIONALNO DISANJE KOD DECE SA ASTMOM
Authors: Jocić Stojanović Jasmina , Živković Zorica , Veković Vesna , Prijić Andreja 
Published: March 2024

Poremećaji disanja kod dece mogu biti posledica funkcionalnih poremećaja disanja sa jedne, i organskih respiratornih bolesti sa druge strane. Simptomi organskih respiratornih bolesti i psihogeni aspekt mogu se preplitati. Jedna od najčešćih hroničnih organskih respiratornih bolesti, na globalnom nivou je astma. Procenjuje se da ovu dijagnozu ima oko 300 miliona ljudi širom sveta i više od 10% pedijatrijske populacije. Iako su razvijene brojne savremene terapjske opcije za lečenje astme, izvestan procenat pacijenata, uključujući i decu, ima loš odgovor na primenjenu terapiju. U grupi ovih pacijenta lekari bi trebalo da razmotre mogućnost postojanja alternativnih dijagnoza, te da prepoznaju eventualno pridružene ili skrivene poremećaje, koji vode lošoj kontroli simptoma bolesti. U tom smislu, primenom više modaliteta kliničkog ispitivanja, kao i rezultata dobijenog Nijmegen upitnikom, moguće je potvrditi prisustvo simptoma disfunkcionalnog disanja i razmotriti da li prisutni simptomi koegzistiraju sa astmom ili predstavljaju nezavisan entitet. Na taj način kroz adekvatne terapijske procedure, ostvarila bi se bolja kontrola simptoma bolesti, izbegla primena nepotrebnih i potencijalno štetnih terapijskih procedura i omogućilo vraćanje uobičajenim životnim navikama, te postiglo poboljšanje opšteg kvaliteta života dece poremećajima disanja.
INFLUENZA VACCINATION IN THE UNITED STATES
Authors: Kalanović Dylag Ivana 
Published: March 2024

Influenza (flu) is a prominent seasonal virus found all over the world that has caused epidemics and deaths for centuries. Prompt immunization of children with chronic medical conditions such as lung disease due to prematurity, asthma, diabetes, heart disease, and those that are immunocompromised is crucial due to their higher risk of influenza complications including superimposed bacterial pneumonia. Childcare providers, pregnant women, and health care personnel are also encouraged, if not mandated, to be vaccinated promptly in order to minimize disease communicability. A current review of vaccine efficacy, as well as patient and physician compliance is presented.
HUMAN PAPILLOMA VIRUS VACCINATION IN THE UNITED STATES
Authors: Kalanovic Dylag Ivana 
Published: March 2024

Human Papilloma Virus (HPV) is the most common sexually transmitted virus in the United States with the highest affected population being adolescents and young adults. Most HPV infections resolve spontaneously, but they are also known to cause genital warts as well as cervical, penile, and anal cancers. In the United States, HPV causes 7,000 male cancers and 15,000 female cancers annually. Due to this high prevalence, the American Academy of Pediatrics recommends vaccinating all males and females against HPV starting between the ages of 11 and 12, and as early as 9 years old. The current clinical indications, vaccine efficacy, and physician and patient compliance will be presented.
PREDIJATRIJSKI ASPEKTI PRIMENE SACCHAROMYCES BOULARDI U SRBIJI
Authors: Stojšić Mirjana 
Published: March 2024

Uvod. U pedijatrijskoj praksi se najčešće koriste probiotici koji sadrže gljivicu Saccharomyces boulardii i bakterije iz grupe Lactobacillus ili Bifidobacterium. Vodiči za primenu probiotika kod dece preporučuju primenu Saccharomyces boulardii u slučaju akutnog gastroenteritisa, eradikacije Helicobacter pylori infekcije, prevencije dijareje udružene sa antibioticima i kod Clostridium difficile enterokolitisa.
Cilj rada.Cilj ovog rada je bio da se ispita moderni aspekt korišćenja Saccharomices Boulardii (Bulardi® Junior, Saccharomices boulardii DBVPG 6763, Abela Pharm, Srbija) u svakodnevnoj pedijatrijskoj praksi.
Metode rada Istraživanje je planirano kao studija preseka rada pedijatara u primarnoj zdravstvenoj zaštiti u Republici Srbiji.
Rezultati. Istraživanjem je obuhvaćen 3 461 ispitanik koji je dobijao navedeni probiotik. Najviše ispitanika je bilo predškolskog uzrasta (59.98%, n=2076), a potom nižeg školskog uzrasta 7-12 godina (15.00%, n=519), dok je najmanje bilo odojčadi (13.98%, n=484) i adolescenata (11.04%, n=382). Ispitanici se nisu statistički značajno razlikovali prema polu. Najčešća indikacija za prepisivanje probiotika je bila dijareja udružena sa antibioticima (64.69%, n=2239), a potom akutni gastroenteritis (34.21%, n=1184), dok su druge dve indikacije bile znatno ređe, Clostridium difficile enterokolitis (0.17%, n=6) i Helicobacter pylori infekcija (0.93%, n=32). Najčešće ordinirani antibiotici uz probiotik su bili penicilini (59.09%, n=2045) i cefalosporini (29.37%, n=1.017), dok su makrolidi, tetraciklini i sulfonamidi bili znatno ređe zastupljeni. U 93.70% (n=3243) slučajeva je Saccharomyces boulardii prepisivan u vidu jedne kapsule od 250 mg na dan. Dužina uzimanja probiotika je bila najčešće 14 dana (47.99%, n=1661).
Zaključak. Pedijatrijski aspekt primene probiotika sa monokulturom Saccharomices boulardii je podjednako korišćenje kod dece oba pola i u svim starosnim grupama dece, ali uglavnom kod dece između 1 i 6 godina. Najčešći indikacije za propisivanje ovog probiotika su dijareja povezana sa antibioticima i akutni gastroenteritis. Probiotik je korišćen sam ili u kombinaciji sa antibioticima, iz grupe penicilina ili cefalosorina.
THE INFLUENCE OF EXPOSURE TO ENVIRONMENTAL TOBACCO SMOKE ON THE PREVALENCE OF ALLERGIC DISEASE SYMPTOMS IN CHILDREN
Authors: Domuz Vujnović Sanela , Domuz Adrijana , Radujković-Bukara Gordana 
Published: March 2024

Introduction: Prenatal and postnatal smoke exposure is generally considered to be a strong risk factor for the development of respiratory symptoms and asthma, particularly in early life. The children exposed to environmental tobacco smoke had statistically significant higher prevalence of symptoms of allergic diseases.
Objective:The aim of this study was to determine the influence of environmental tobacco smoke exposure on the prevalence of allergic diseases symptoms in children aged 6 to 15 years in Republic of Srpska.
Methods: Our study was conducted as a cross-sectional study and included 3,000 children aged 6 to 15 years from 13 primary schools in Republic of Srpska. The allergic diseases symptoms and environmental tobacco smoke exposures were assessed by questionnaire, which was completed by the parents.
Results: Maternal smoking during pregnancy was reported by 9,2% participants. Children were classified into two groups according to smoking status of householders: none (54,8%), and > 1 (45,2%). Children were not exposed to environmental tobacco smoke (62,9%) or they spent a short time in these rooms (< 1 hour 17,4%; 1-5 hours 14,4%; > 5 hours 5,3%) in our study. Children exposed to environmental tobacco smoke were reported a higher prevalence of wheezing (9,5%), allergic rhinitis (28,0%) and eczema (6,9%) than unexposed children (7,7%, 21,4% and 3,9%, respectively).
Conclusion: In summary, our results support the need for public policy to protect children from environmental tobacco smoke exposure in their environment. Additional studies are needed to clarify the association betweenenvironmental tobacco smoke exposure and childhood allergic diseases.
RANA DIJAGNOZA I LEČERNJE ANOMALNOG ISHODIŠTA LEVE KORONARNE ARTERIJE
Authors: Prijić Sergej , Košutić Jovan , Stajević Mila , Ninić Sanja , Šehić Igor , Popović Saša , Bjelaković Bojko , Vukomanović Vladislav 
Published: March 2024

Anomalno ishodište leve koronarne arterije iz plućne arterije (ALCAPA) predstavlja retku kongenitalnu anomaliju, koja se javlja sa učestalošću od 1:300.000 živorođene dece i kod koje ishemija miokarda nastaje usled fenomena »koronarne krađe«.
Dvomesečno odojče je hospitalizovano sa znacima teške kongestivne srčane insuficijencije, koja je bila praćena metaboličkom acidozom, povišenim koncentracijama kardiospecifičnih enzima i proteina, radiografskim uvećanjem srčane senke i elektrokardiografskim znacima ishemije miokarda. Ehokardiografski je registrovana značajna dilatacija i hipokontraktilnost leve komore uzrokovani anomalnim ishodištem leve koronarne arterije iz plućne arterije i prisutnim fenomenom «koronarne krađe». Dijagnoza je potvrđena angiografijom koronarnih krvnih sudova. U uzrastu od tri i po meseca učinjena je kardiohirurška intervencija po tipu transfera leve koronarne arterije sa urednim operativnim i dugoročnim postoperativnim tokom. Kontrolni nalazi, tokom dvogodišnjeg praćenja bolesnika, su ukazali na kompletni oporavak.
Kod nelečenih bolesnika sa ALCAPA smrtnost u prvoj godini iznosi 90%. Međutim, prognoza oboljenja je značajno poboljšana kao rezultat mogućnosti rane ehokardiografske dijagnoze i poboljšanja hirurške tehnike.
SMRTNOST ODOJČADI U SRBIJI U PERIODU OD 2007 DO 2016.GODINE
Authors: Nikolić Katarina , Ignjatović Aleksandra 
Published: March 2024

Uvod: Smrtnost odojčadi је оsetljiv pokazatelj zdravstvenog stanja stanovništva i zdravstvene zaštite dece.
Cilj rada:Cilj rada је bio da se analizira smrtnost odojčadi u Srbiji u višegodišnjem periodu.
Metode rada: Ova epidemiološka studija je sprovedena kao retrospektivna za period с2007-2016.godine na osnovu podataka dobijenih iz javno dostupnih izvora: Zdravstveno-statističkih godišnjaka Srbije koje objavljuje Institut za javno zdravlje Srbije. Preuzeti su podaci о broju živorodjene dece i broju umrle odojčadi prema polu, starosnoj strukturi i prema dijagnozi. Stopа mortalitetа оdojčadi је izračunata na osnovu preuzetih podataka za oba pola. Тrend i godišnja procentualna promena mortaliteta odojčadi sa 95% intervalom poverenja (95%CI) su izračunati joinpoint regresionom analizom. Optimalan broj prelomnih tačaka dobijen je metodom Monte Сarlo permutacijе. Zа аnalizu trenda korišćen je programski paket Joinpoint Regression Program verzija 4.1.ij0 . Promenа trenda је smatrana statistički značajnom ukoliko je p-vrednost <0,05.
Rezultati: U Srbiji је u periodu 2007-2016.godinа umrlo 4213 odojčadi i to više muškog pola (57,3%). Najveći mortalitet odojčadi u pomenutom periodu је zabeležen 2007. god. ( 7,11 na 1000 živorodjene dece), а najmanji 2015.god.( 5,27 na 1000 živorodjene dece). U posmatranom periodu stopa mortaliteta odojčadi konstantno i statistički značajno је opadala kako kod muške, tako i kod ženske dece, а mortalitet novorodjenčadi је dominirao sa 71,0% u ukupnom mortalitetu odojčadi.
Zaključak: Rezultati ovog istraživanja su pokazali da u periodu 2007-2016. godina u Srbiji postoji konstantan trend smanjenja smrtnosti odojčadi, što је povoljan indikator zdravstvenog stanja nacije i zdravstvene zaštite dece.
OBLICI NEINVAZIVNE VENTILACIJE
Authors: Veković Vesna , Veković Borko , Živković Zorica , Sekulović Gordana , Tomašević Milena 
Published: March 2024

U Srbiji se pre vremena godišnje rodi oko četiri hiljade beba i sve one su u riziku da razviju hroničnu plućnu bolest(HPB) Ovo stanje karakteriše visok mortalitet i morbiditet. Jedan od značajnih etioloških faktora koji doprinose razvoju HPB- a je dugotrajna mehanička ventilacija. Mehanička ventilacije putem endotrahealnog tubusa za mnoge prevremeno rođene bebe predstavlja vid respiratorne potpore koja spašava život. Ipak, u nekim slučajevima mehanička ventilacija dovodi do oštećenja pluća i pojave hronične plućne bolesti kod prematurusa. Uprkos primeni antenatalne kortikosteroidne terapije, primeni plućnog surfaktanta i različitih modova konvencionalne i visokofrekventne oscilatorne ventilacije više od 40% novorođenčadi rođene pre 28 nedelje gestacije i dalje razvija hroničnu plućnu bolest.Smanjenje trajanja mehaničke ventilacije, rana ekstubacija i primena neinvazivnih metoda respiratorne potpore su mere koje dokazano manje oštećuju pluća.
UPDATE ON FOOD ALLERGIES
Authors: Radulović Marija , Filipović Djordje , Filipović Ivana 
Published: March 2024

Food allergy has been defined as adverse reaction to food in which “immunological mechanism have been demonstrated”. The clinical presentation of food allergy involves a large spectrum of symptoms ranging from skin like urticaria, angioedema, atopic eczema, dermatitis, gastrointestinal (vomiting, colic, abdominal pain, diarrhea, constipation), respiratory (rhinorrhea, sneezing, cough, dyspnea). According to a recent review the point prevalence of self-reported food allergy is approximately six times higher than challenge food allergy. A proper diagnosis is necessary for a sufficient and safe management. The core stone of diagnosis of food allergy is a careful dietary history. Mostly food allergies are self reported, but also a great number of tests are available. The most widely used tests for food allergies diagnosis are: skin prick tests (SPT), specific IgE (sIgE), component resolved diagnosis (CRD) and the atopy patch test (APT). Besides food avoidance there is also growing interest in the effectiveness of potential immunomodulatory treatment approaches, including sublingual and oral immunotherapy to induce tolerance, particularly for peanut allergy.
The HUBUNGAN PERSEPSI MAHASISWA TERHADAP MATA KULIAH DENGAN PRESTASI BELAJAR PENDIDIKAN KEWARGANEGARAAN
Authors: Damanhuri Damanhuri , Yuhana Yuyu 
Published: March 2024

ABSTRACT
Citizenship Education (PKn) has a very important role, through Civics courses it is hoped that it will be able to form students who have national insight and homeland ideals. The purpose of this research is to determine the relationship between student perceptions of courses and Civics learning achievement. The research hypothesis is that there is a relationship between student's perceptions of the course and their civics learning achievement. The method in this research is a survey using correlation techniques. The entire research population consisted of 1st-semester students in the Primary School Teacher Education study program, FKIP, Sultan Ageng Tirtayasa University, Class of 2022/2023. The sample was obtained using a proportional random sampling system taking 30% of the population. Based on the results of data analysis, shows that the more positive a student's perception of a course is, the higher their learning achievement tends to be with a correlation coefficient of 0.658. It can be concluded that Civics learning achievement can be improved by building students' positive attitudes towards the subject.
PENGARUH LABEL NEGATIF TERHADAP PEMULUNG DI MASYARAKAT (STUDI KOTA TANJUNGPINANG)
Authors: Ira Lisa , Erdawati Lidya , Widiyani Heni 
Published: March 2024

Abstract
Some people's perspectives see waste pickers in a negative light, assuming that they interfere with the safety and comfort of the community. This negative view arises as a result of irregularities committed by unscrupulous scavengers, for example by taking goods that have not been disposed of by their owners. In this case, the stigma towards the negative label of scavengers that exists in the community has a direct influence on the activities carried out by scavengers, especially on scavengers who usually go around both on the streets and around people's housing. This research was conducted to answer and examine how the influence of negative labeling in society on waste pickers in Tanjungpinang City. The research method used in this research is qualitative research with descriptive methods with the data collection techniques used in this research are observation and interviews. As an analysis knife in this research, two theories are used as references, namely labeling theory and stigma theory. The results show that negative labeling of waste pickers affects other waste pickers who do not commit irregularities, honest waste pickers who work only to make a living for their families are affected by the label. This means that the label creates a stigma in the community towards waste pickers.
IMPLEMENTEASI KEBIJAKAN BARANG MILIK DAERAH PADA BADAN PENGELOLAAN KEUANGAN DAN ASET DAERAH (BPKAD) PROVINSI BANTEN
Authors: Mahmud Toni Anwar , Dewiyanti Rina , Komara Syifa Rachmania 
Published: March 2024

ABSTRACT
Regional Property must be managed properly and correctly by paying attention to functional principles, legal certainty, transparency, efficiency, accountability and certainty of value. The Banten Provincial Government, to be able to implement the provisions of Government Regulation Number 27 of 2014 and Article 511 paragraph 1 of the Minister of Home Affairs Regulation Number 19 of 2016 concerning Guidelines for Management of Regional Property, has issued Banten Province Regional Regulation Number 1 of 2019 concerning the management of regional property. However, in implementation there are still several obstacles faced by Banten Province, especially the Regional Financial and Asset Management Agency (BPKAD) in managing regional property in several cycles. Based on this and considering the importance of Regional Property Management, the regional government of Banten Province together with BPKAD is expected to be able to find efforts and implement appropriate and reliable strategies in managing regional property, especially in planning activities and budgeting needs for regional property.