bluuebunny/crossref_metadata_2025_split huggingface dataset:
Ratiometric fluorescence determination of trace nitrite in kimchi based on BSA- templated Cu-Au alloyed nanoclusters (BSA-CuAuNCs)
Authors: Cheng Baoxin , Xia Xiuhua , Huang Jiachen , Yu Hang , Xie Yunfei , Guo Yahui , Yao Weirong , Qian He , Cheng Yuliang L. 
Published: February 2024

Abstract
A ratiometric fluorescence quenching sensor was designed for trace nitrite detection in kimchi. BSA-templated Cu-Au alloyed nanoclusters (BSA-CuAuNCs) with promoted acid resistance were synthesized by using bovine serum albumin (BSA) and ascorbic acid (AA) as the ligand and the reductant respectively, which showed bimodal emission at 395 nm and 655 nm (excitation of 310 nm). Interestingly, the emission at 655 nm of BSA-CuAuNCs could be quenched significantly under acidic conditions by nitrite, while the peak at 395 nm remained constant. The ratiometric fluorescence sensor showed good linearity in the range of 1–60 µM with a limit of detection (LOD) of 0.12 µM and was further applied to nitrite detection in kimchi with recoveries of 95.03%-107.20% (relative standard deviations (RSDs) of 1.82%-4.26%), which demonstrated the potential of as-constructed sensor for trace nitrite detection in real food samples.
Combined Use of Niraparib Enhanced the Inhibitory Effect of Anti-GD2 Antibody on Osteosarcoma Cells
Authors: Wenyao Chen , Shuai Ma , Yifeng Fan , Xinzhi Li , Xiangyong Que 
Published: February 2024

Abstract

Purpose
To study the inhibitory effect of Niraparib in combination with Anti-GD2 Antibody on Osteosarcoma.
Methods
The migration ability of OS cells was detected by scratch test. Transwell experiment and CCK8 assay were used to detect the invasion and proliferation. WB was used to detect BALP and CICP protein expression. The mRNA expression of BALP and CICP was detected by QRT-PCR.
Results
Scratch test showed that the distance between cells in Niraparib + GD2 group was 1.07 ± 0.04 and 1.06 ± 0.04 at 48h, both p < 0.05, and the differences were statistically significant. Transwell experiment showed that the number of invasive cells was 21 ± 1.5 in Niraparib + GD2 group, p < 0.05, and the differences were statistically significant. CCK8 assay showed that the absorbance of Niraparib + GD2 group was 0.16 ± 0.10 on day 5, p < 0.05, and the differences were statistically significant. WB showed that compared with the Control group, the semi-quantitative results of BALP expression in Niraparib + GD2 group were 0.751 ± 0.135 and CICP expression were 1.086 ± 0.115, both p < 0.05, and the differences were statistically significant. QRT-PCR showed that the absorbance of Niraparib + GD2 group was 0.173 ± 0.065 and 0.170 ± 0.078 on day 14, both p < 0.01, and the differences were statistically significant.
Conclusion
Niraparib combined with Anti-GD2 Antibody has a more prominent inhibitory effect on OS.
Towards an Autism Spectrum Disorder (ASD) care agent for social interaction
Authors: Gupta Prashant K. , Mazumdar Bireshwar Dass , Komaragiri Rama S , Bhurani Kashish , Chadha Rubina 
Published: February 2024

Abstract
Autism Spectrum Disorder (ASD) is a neurological disorder that impacts a subject's ability to be involved in a social interaction. A large body of work exists on the detection of ASD using machine learning (ML) and deep learning (DL) algorithms. Further the use of eXplainable artificial intelligence (XAI) algorithms is being advocated in the healthcare domain (on account of the 'black-box' nature of DL algorithms), to the best of our knowledge, no social interaction model based eXplainable Autism Spectrum Disorder (ASD) care agent exists for social interaction training of an ASD subject. Therefore, we make a beginning in this direction through this work. We present a novel architecture of an eXplainable ASD care agent for social interaction training of ASD subjects, with an underlying intelligent AI algorithm. We elucidate its working through six representative social interaction scenarios and put forward some practical considerations when the agent is put in practice with the ASD subject. We hope that the interested researchers can develop further on the work in future.
How to Tell a Story about Gender Inequality in 360°-Volumetric-Video to Virtual Reality Users?
Authors: Vosmeer Mirjam , Hartmann Tilo , Barreda-Ángeles Miguel , Roth Christian 
Published: February 2024

Abstract

360°-video stories represent a popular new story format, particularly in the community striving to use “VR for Good”. Yet, due to the novelty of the format, many questions about the right “grammar” to tell effective 360°-video stories exist, including questions about how to engage users in interactive and immersive stories via VR without overwhelming them. In the present approach, with the help of a professional VR design agency, we developed Amelia’s Dream, a novel volumetric-video experience that addresses current issues of gender inequality. In a pre-registered quantitative between-subjects experiment with N = 103 participants, we experimentally varied two versions of Amelia’s Dream to illuminate how a basic form of story interactivity influences users’ memorization of the story (message recognition) and the overall perceived persuasive appeal of the story. We explore user engagement (i.e., presence and transportation) as potentially underlying mechanisms. In addition, we tap into the question to what extent users should be recognized in a volumetric video, and examine if users memorize story fragments better depending on whether or not the VR storyteller acknowledges their presence by establishing eye-contact with them. Contrary to expectations, our findings suggest that the basic form of story interactivity that we introduce might undermine users’ learning from 360°-stories. However, in line with expectations, a storytellers’ eye-contact might promote the stories’ effectiveness.
Unveiling the Landscape of Human Pose Estimation
Authors: Yang Jianjun , Dasgupta San , Liu Wenjiao , Shen Ju , Payne Bryson , Luo Ying , Liu Ruixu , Nguyen Tam 
Published: February 2024

Abstract
This paper presents a comprehensive survey and methodology for deep learning-based solutions in articulated human pose estimation (HPE). Recent advances in deep learning have revolutionized the HPE field, with the capturing system transitioning from multi-modal to a regular color camera and from multi-views to a monocular view, opening up numerous applications. However, the increasing variety of deep network architectures has resulted in a vast literature on the topic, making it challenging to identify commonalities and differences among 1 diverse HPE approaches. Therefore, this paper serves two objectives: firstly, it provides a thorough survey of over 100 research papers published since 2015, focusing on deep learning-based solutions for monocular HPE; secondly, it develops a comprehensive methodology that systematically combines existing works and summarizes a unified framework for the HPE problem and its modular components. Unlike previous surveys, this study places emphasis on methodology development in order to provide betters insights and learning opportunities for researchers in the field of computer vision. The paper also summarizes and discusses the quantitative performance of the reviewed methods on popular datasets, while highlighting the challenges involved, such as occlusion and viewpoint variation. Finally, future research directions, such as incorporating temporal information and 3D pose estimation, along with potential solutions to address the remaining challenges in HPE, are presented.
A novel bio-mass resveratrol-modified lignin-based phenolic resin with high T g and improved mechanical properties
Authors: Zhang Yimiao , Meng Fuliang , Hu Zhenguo , Jia Yufei , Chen Zeyu , Fei Hongwei , Zhou Dapeng , Yuan Xinhua 
Published: February 2024

Abstract

The preparation of green bio-based phenolic resin with high performance has far-reaching significance for sustainable development and is an important research direction for researchers in recent years. In this study, a novel resveratrol-modified lignin-based phenolic phenolic resin (R-LPF) with ultra-high Tg and improved mechanical properties was synthesized with biomass phenol of resveratrol and lignin as raw materials. The curing behaviors of phenolic resin (PF), lignin phenolic resin (LPF) and R-LPF were investigated. The thermal mechanical properties, thermal stability, comprehensive mechanical properties, frictional properties and morphology were systematically tested and analyzed. The results show that the highest Tg of the modified R-LPF reaches 346.2°C, which is much higher than that of traditional PF, and the thermal and mechanical properties of the novel R-LPF are also significantly improved. The Ts reaches 231.5°C, and the residual carbon rate reaches 66.2% at 800°C. The improved tensile strength, bending strength and impact strength are 28.72 ± 1.10 MPa, 57.58 ± 1.95 MPa and 3.14 ± 0.19 MPa, respectively. Compared with PF and LPF, the wear resistance is also significantly improved. Due to the rigid structure and high crosslinking density, the modified resin has excellent properties and provides broad application prospects in resin-based friction materials for the bioresource of resveratrol.
Feature identification using hypotheses of relevance and a 2D-cascade of SEQENS ensembles
Authors: Arlandis Joaquim , Llobet Rafael , Navarro-Cerdán J.Ramón , Arnal Laura , Signol François , Perez-Cortes Juan-Carlos 
Published: February 2024

Abstract

SEQENS is an ensemble method aimed at feature identification that has demonstrated strong performance in identifying relevant features across different synthetic tasks (Signol et al, 2023). In this paper, we present a framework based on SEQENS spanning the following contributions: (1) computing the hypergeometric p-value of the features of a SEQENS output ranking in order to threshold into relevant and non-relevant features; (2) extending SEQENS by introducing the use of preselected features as hypotheses of relevance in the SFS, which may help to attract other features that might exhibit weak correlation with the target on their own, but gain relevance when combined with the preselected ones; (3) designing an automated process based on a 2D-cascade of SEQENS ensembles to obtain a \emph{purged feature set}, or PFS, i.e., having as many relevant features, and as few non-relevant, as possible; (4) integrating all the former techniques so that the PFS is used as in a SEQENS ensemble, which corresponds the complete framefork named pc-SEQENS.
The performance of pc-SEQENS is measured on a task of gene expression identification using the E-MTAB-3732 public database and synthetic groundtruths. pc-SEQENS is compared to other feature identification state-of-the-art methods, including SEQENS. On average, the proposed framework identifies better the relevant genes, specially in the most unfavorable sample-to-dimension rates, and exhibits a stronger stability.
Research on Axial Stress Ultrasonic Measurement Method for In-service Pipes Based on Bi-directional Probe
Authors: Li Yukun , Wang Longsheng , Zhang Chen , Liu Xin , Wang Dongying 
Published: February 2024

Abstract

There is a linear relationship between the change in ultrasonic critical refraction longitudinal wave time of flight and the change in stress, and the change in ultrasonic time of flight of the outer wall surface of the in-service pipe and the zero stress calibration specimen can be measured to calculate the axial stress of the pipe during operation. The difference between the calibration specimen and the measured pipeline steel batch and yielding degree will lead to inaccurate ultrasonic time of flight measurement results of zero stress, which in turn will reduce the reliability of stress measurement results. In order to solve the errors caused by calibration problems in the ultrasonic stress measurement process, this paper firstly deduces the calculation formula for axial stress ultrasonic measurement in the bi-directional stress state of the pipe wall, and proves that axial stress measurement requires both axial and circumferential ultrasonic time of flight measurements. Preparation of X80 spiral welded seam steel pipe axial and circumferential plate specimens, the first measurement of ultrasonic time of flight in different directions under zero stress state; followed by axial and transverse plate specimens one-way tensile test, respectively, to calibrate the relationship between stress and ultrasonic time of flight of the two specimens; finally, based on the results of anisotropic ultrasonic time of flight measurement of pipeline steel specimens and axial and transverse plate specimens one-way Finally, based on the anisotropic ultrasonic time of flight measurement results of pipeline steel specimens and the calibration experimental results of axial and transverse plate specimens in one-way tensile test, an axial stress ultrasonic measurement method is proposed for the bi-directional stress state of pipeline wall. The usability of the measurement results of the method was verified by pipeline pressure testing using bi-directional ultrasonic probes.
Transseptal Puncture in Children Weighing Less Than 20 kg in Invasive Cardiac Catheterization and Electrophysiology
Authors: Maze Aydemir Merve , Bekir Yukcu , Candas Kafali Hasan , Gulumser Sisko Sezen , Hacer Kamali , Alper Guzeltas , Yakup Ergul 
Published: February 2024

Abstract
Introduction: Transseptal puncture (TSP) is a widely utilized technique for left-sided electrophysiological studies (EPS), interventions in left heart lesions, or creating interatrial shunts in congenital heart diseases (CHD). This study aims to evaluate the outcome of TSP in children under 20 kg.
Methods: This retrospective study analyzed TSP procedures in infants and children <20 kg between December 2015 and December 2021. TSPs were performed with a biplane angiography system in the catheter angiography laboratory. A Brockenbrough needle (BRK Transseptal Needle; Abbott/St.Jude Medical, Inc) was used for TSP. In patients whose Brockenbrough needles could not achieve sufficient patency, TSP was performed by applying cautery energy over the Brockenbrough needle.
Results: Twenty-one patients were studied (8 females, median age 2.6 years, median weight 12 kg), and 66% required TSP for CHD, including HLHS and pulmonary hypertension. The CHD group had younger patients (median age: 6.6 months) with smaller weights (median: 5.7 kg) compared to the catheter ablation group. TSP success rate was lower in patients with CHD, especially those with complex anatomy. Radiofrequency energy was used without complications in three cases when traditional methods failed. In four patients, the septum couldn't be traversed. The median weight of the patients who failed TSP was 3,4 kg. The only major complication was pericardial tamponade developed in two patients diagnosed with hypoplastic left heart syndrome.
Conclusion: TSP is a safe option when carefully selected but carries higher risks in complex CHD with abnormal cardiac anatomy compared to patients with normal anatomy used for electrophysiology procedures.
Controlled synthesis of high performance SAPO-34 with sheet-like morphology and small particle size using concentrated gel system
Authors: Liang Ni , Wang Haiyan , Wang Yujia , Kang Lei , Bai Yingzhi , Sun Na 
Published: February 2024

Abstract

A strategy was devised for the synthesis of SAPO-34, which involved a concentrated gel system-assisted two-step crystallization method. This strategy effectively controlled the size and morphology of SAPO-34. The successful synthesis of SAPO-34 crystals with micron-scale cubic morphology and nano-scale sheets were achieved using triethylamine as a low-cost template. The paper thoroughly examined the growth evolution that occurs during the crystallization process, and it delved into the factors such as gel concentration and crystallization conditions in the synthesis. Furthermore, potential theories regarding nucleation and growth mechanisms were suggested. A systematic study was conducted to examine how the morphology and acidity of SAPO-34 zeolites impact their catalytic performance. The results confirmed that concentrated gel enhanced nucleation facilitated formation small crystals, therefore sheets under suitable crystallization conditions. The SAPO-34 with low silicon content and lamellar structure was effectively produced through a two-step crystallization within a gel system of H2O/Al2O3 = 30, with a thickness of approximately 50–300 nm. SAPO-34 nanosheets demonstrated a substantial enhancement in catalytic performance, with a catalytic life of 370 min and an 84.1% selectivity towards light olefins.
Superantigens, Antigen Precision and Their Applications
Authors: Zuo Peijun , Zuo Longlong , Li Zhihong , Li Liping 
Published: February 2024

Abstract
The aim of this study was to find a method to identify epidemic and sporadic pathogen strains.
The method includes A. detecting the antigenic amino acid sequence of the pathogen strain to determine the primary superantigen. B. If the primary superantigen contains tryptophan, the pathogen strain is an epidemic strain. C. If the primary superantigen does not contain tryptophan amino acid, it is a sporadic strain. D. Determine the outbreak time interval between the pathogen strain and the reference strain based on the increase in antigen precision between the pathogen strain and the reference strain.
Results: The method can predict whether a series of infectious diseases will become epidemic or scattered, as well as the date of outbreak, such as severe acute respiratory syndrome 1 (SARS I), Middle East Respiratory Syndrome (MERS) and Coronavirus Disease 2019 (COVID-19, SARS II).
Influenza and acute viral infection prevention in children with recurrent respiratory pathology
Authors: Zakirova A. M. , Moroz T. B. , Pokrovskaya E. M. , Faizullina R. A. , Khaliullina S. V. , Vakhitov Kh. M. , Sadrieva L. N. , Sabirzyanova M. G. , Shayapova D. T. , Samorodnova E. A. , Palmova L. Yu. , Kadriev A. G. , Rashitova E. L. , Zaripov I. R. , Kadriev D. A. 
Published: February 2024

Introduction. Despite numerous scientific works devoted to the problem of acute respiratory diseases, its relevance does not decrease throughout the world, since serious complications with an unfavorable prognosis are possible.Aim. To evaluate the effectiveness of preventive antiviral therapy in children with recurrent respiratory pathology.Materials and methods. Under observation were 43 children (average age 7.43 ± 3.05 years) with recurrent respiratory pathology, who underwent health treatment in the summer period once for 14 days. The main group consisted of 22 children who were prescribed the antiviral therapy as a monotherapy for prophylactic use. The comparison group included 21 patients who underwent preventive treatment using nasopharyngeal irrigation with local antiseptic chemicals. The observation period was 3 months after prophylactic treatment.Results and discussion. After preventive treatment, the total number of episodes of ARI during the observation period in the main group in relation to the comparison group was according to nosologies: acute pharyngitis (p = 0.0317), exacerbation of chronic tonsillitis (p = 0.0137), acute rhinitis (p = 0.0692), rhinosinusitis (p = 0.0429). In the main group, during the observation period, when episodes of upper respiratory tract diseases occurred, antibacterial drugs were prescribed statistically significantly less frequently (p = 0.0296). After the preventive course, compared with the initial data, there was a decline in the number of cases of upper respiratory tract diseases per child on average per quarter. Thus, in the main group, a more pronounced significant difference was revealed in all nosological forms (acute rhinitis, rhinosinusitis p = 0.0081, acute pharyngitis p = 0.0129, tonsillopharyngitis p = 0.0384). In the comparison group – respectively: p = 0.0426; 0.0387; 0.0439.Conclusions. Carrying out preventive treatment as monotherapy in children with recurrent respiratory pathology demonstrated high effectiveness (86.37%) of the antiviral therapy.
The vitamin D status and the levels of β1- and β2-defensins in children and adolescents with different forms of pulmonary TB
Authors: Panova L. V. , Averbakh M. M. , Ovsуankina E. S. , Zakharova I. N. , Karasev A. V. , Khokhlova Yu. Yu. , Sterlikova S.  S. 
Published: February 2024

Introduction. The basic research demonstrated an important role of vitamin D in strengthening the immune response to Mycobacterium tuberculosis and proved its effect on the production of antimicrobial peptides. However, the correlation between the levels of vitamin D and defensins (β1 and β2) in children and adolescents with different forms of pulmonary TB was not studied.Aim. To study the correlation between the levels of vitamin D and β1- and β2-defensins in children and adolescents with different forms of pulmonary TB.Materials and methods. We carried out a prospective study of 75 patients with pulmonary TB aged 2–17 years (52 new cases and 23 retreatment cases) in 2021–2023. The levels of 25(OH)D and β1- and β2-defensins were determined at admission to hospital.Results. Out of 75 patients 2.7% had adequate levels of vitamin D (more than 30 ng/mL), 13.3% had insufficient levels of vitamin D (20 to 30 ng/mL), 34.7% had deficient levels of vitamin D (10 to 20 ng/mL), and 49.3% had severe deficiency of vitamin D (less than 10 ng/mL). We established a direct correlation between 25(OH)D and β1-defensin levels (p = 0.004766) and lack of correlation between 25(OH)D and β2-defensin levels. We discovered significant differences in the levels of 25(ОН)D and β1-defensin between new and retreatment cases: 13.10 ± 1.04 ng/mL and 8.74 ± 1.07 ng/mL (p = 0.004644) and 6.66 ± 0.79 ng/mL and 4.0 ± 0.85 ng/mL (p = 0.024816), respectively.Conclusion. The differences in the levels of calcidiol and β1-defensin between new and retreatment cases witness an impaired function of one of the innate non-specific immunity components during long-lasting advanced pulmonary TB in children and adolescents.
Spatiotemporal assessment of rainfall variability and its characteristics over Rapti River Basin, India
Authors: Malani Urvashi , Yadav Sanjaykumar M. 
Published: February 2024

Abstract

The determination of rainfall characteristics of a basin is obligatory for mitigation planning and adaptation. This study presents the spatiotemporal analysis of gridded precipitation to understand the variability and seasonality over the Rapti Basin. This basin is affected by frequent flooding; hence it becomes necessary to understand the variability of rainfall. To carry out this analysis, daily precipitation data is extracted for 22 grids for 30 years (1990–2020) of high resolution. Extreme rainfall indices are computed as per the threshold decided by the Indian Meteorological Department (IMD). To determine the trend of the rainfall, Mann Kendall (MK) test, Modified MK test and Innovative Trend Analysis was used and magnitude of trend was determined using slope. Trends of daily rainfall, annual, and seasonal rainfall were determined. Annual rainfall has shown significant decreasing trend over the basin. Monsoon season has a noticeable tendency, but other seasons have only seen small shifts. From all the rainfall indices, PRCPTOT and SDII showed a decreasing trend with Sen Slope of −2.56 and 3.00 respectively. While examining the variance in precipitation across the basin, this study will be helpful.