bluuebunny/crossref_metadata_2025_split huggingface dataset:
Mid-term outcomes of physician-modified endograft therapy for complex aortic aneurysms
Authors: Shibata Tsuyoshi , Mitsuoka Hiroshi , Iba Yutaka , Hashizume Kenichi , Hongo Norio , Yasuhara Kiyomitsu , Kuwada Noriaki , Katada Yoshiaki , Hashiguchi Hitoki , Uzuka Takeshi , Murai Yuta , Nakajima Tomohiro , Nakazawa Junji , Kawaharada Nobuyoshi 
Published: March 2024

AbstractOBJECTIVESOur goal was to evaluate early and mid-term outcomes of physician-modified endografting for pararenal and thoraco-abdominal aortic aneurysms from 10 Japanese aortic centres.METHODSFrom January 2012 to March 2022, a total of 121 consecutive adult patients who underwent physician-modified endografting for pararenal and thoraco-abdominal aortic aneurysms were enrolled. We analysed early and mid-term postoperative outcomes, including postoperative complications and mortality.RESULTSThe pararenal and thoraco-abdominal aortic aneurysm groups included 62 (51.2%) and 59 (48.8%) patients, respectively. The overall in-hospital mortality rate was 5.8% (n  =  7), with mortality rates of 3.2% (n  =  2) and 8.5% (n  =  5) in pararenal and thoraco-abdominal aortic aneurysm groups, respectively (P = 0.225). Type IIIc endoleaks occurred postoperatively in 18 patients (14.9%), with a significantly higher incidence (P = 0.033) in the thoraco-abdominal aortic aneurysm group (22.0%, n  =  13) than in the other group (8.1%, n  =  5). Major adverse events occurred in 7 (11.3%) and 14 (23.7%) patients in pararenal and thoraco-abdominal aortic aneurysm groups (P = 0.074), respectively. The mean follow-up period was 24.2 months. At the 3-year mark, both groups differed significantly in freedom from all-cause mortality (83.3% and 54.1%, P = 0.004), target aneurysm-related mortality (96.8% and 82.7%, P = 0.013) and any reintervention (89.3% and 65.6%, P = 0.002). Univariate and multivariate regression analyses demonstrated that ruptures, thoraco-abdominal aortic aneurysms and postoperative type IIIc endoleaks were associated with an increased risk of all-cause mortality.CONCLUSIONSThe mid-term outcomes of physician-modified endografting for pararenal and thoraco-abdominal aortic aneurysms were clinically acceptable and comparable with those in other recently published studies. Notably, pararenal and thoraco-abdominal aortic aneurysms represent distinct pathological entities with different postoperative outcomes.
Bayesian deep neural network for low-carbon scheduling strategy planning of V2G
Authors: Wang Fei , Jiang Bin , Hu Linlin , Jin Hao , Yu Qi , Shi Ye 
Published: March 2024

Abstract
With the increasing adoption of electric vehicles, the Vehicle-to-Grid (V2G) model has become crucial in integrating renewable energy generation. However, challenges exist in developing grid scheduling strategies that are tailored to different regions, as well as in quantifying the economic benefits and carbon emissions associated with such scheduling. To address these issues, our study proposed a novel V2G low-carbon scheduling strategy planning method based on Bayesian neural networks. Initially, we established a stochastic V2G model that incorporated grid and electric vehicle scheduling, along with a mathematical model that captured the random behavior of EV users, enabling us to capture the essential characteristics of scheduling planning. Subsequently, we employed an enhanced Bayesian deep neural network to learn and assimilate these scheduling planning characteristics, allowing for the provision of a grid scheduling strategy that ranks economic benefits based on weighted priorities. Furthermore, we conducted simulation experiments within the coverage area of the Internet of Things in Energy (IoTE) to gather scheduling characteristics. The experimental results demonstrated that our method outperformed other deep learning models in terms of voltage amplitude stability during the grid scheduling process, showcasing superior robustness and accuracy. Moreover, we evaluated the economic benefits of the scheduling model and compared it with the original V2G scheduling model. The findings revealed that our model exhibited higher economic benefits and lower carbon emissions. Considering the future challenges of low-carbon urban planning, our method holds significant potential in terms of grid scheduling economic benefits and carbon emission indicators.
Eight Times Four Bialgebras of Hypergraphs, Cointeractions, and Chromatic Polynomials
Authors: Ebrahimi-Fard Kurusch , Fløystad Gunnar 
Published: March 2024

Abstract
The bialgebra of hypergraphs, a generalization of W. Schmitt’s Hopf algebra of graphs [25], is shown to have a cointeracting bialgebra structure, giving a double bialgebra in the sense of L. Foissy, who has recently proven [15] that there is then a unique double bialgebra morphism to the double bialgebra structure on the polynomial ring ${\mathbb Q}[x]$. We show that the associated polynomial is the hypergraph chromatic polynomial. Moreover, hypergraphs occur in quartets: There is a dual, a complement, and a dual complement hypergraph. These correspondences are involutions and give rise to three other double bialgebras, and three more chromatic polynomials. In addition to these two quartets of bialgebras we give six more, including recent bialgebras of hypergraphs introduced by M. Aguiar and F. Ardila [1] and by L. Foissy [17].
A Bivalent Adenovirus-Vectored Vaccine Induces a Robust Humoral Response, but Does Not Protect Cynomolgus Macaques Against a Lethal Challenge With Sudan Virus
Authors: van Tol Sarah , Fletcher Paige , Feldmann Friederike , Mukesh Reshma K , Port Julia R , Gallogly Shane , Schulz Jonathan E , Rhoderick Joseph F , Makinson Rebecca , Carmody Aaron , Myers Lara , Lovaglio Jamie , Smith Brian J , Okumura Atsushi , Shaia Carl , Saturday Greg , Marzi Andrea , Lambe Teresa , Munster Vincent J , van Doremalen Neeltje 
Published: March 2024

Abstract
The most recent Sudan virus (SUDV) outbreak in Uganda was first detected in September 2022 and resulted in 164 laboratory-confirmed cases and 77 deaths. There are no approved vaccines against SUDV. Here, we investigated the protective efficacy of ChAdOx1-biEBOV in cynomolgus macaques using a prime or a prime-boost regimen. ChAdOx1-biEBOV is a replication-deficient simian adenovirus vector encoding SUDV and Ebola virus (EBOV) glycoproteins (GPs). Intramuscular vaccination induced SUDV and EBOV GP-specific immunoglobulin G responses and neutralizing antibodies. Upon challenge with SUDV, vaccinated animals showed signs of disease like those observed in control animals, and no differences in survival outcomes were measured among all 3 groups. Viral load in blood samples and in tissue samples obtained after necropsy were not significantly different between groups. Overall, this study highlights the importance of evaluating vaccines in multiple animal models and demonstrates the importance of understanding protective efficacy in both animal models and human hosts.
Single-cell genomics of a bloom-forming phytoplankton species reveals population genetic structure across continents
Authors: Gollnisch Raphael , Ahrén Dag , Rengefors Karin 
Published: March 2024

Abstract
The study of microbial diversity over time and space is fundamental to the understanding of their ecology and evolution. The underlying processes driving these patterns are not fully resolved but can be studied using population genetic approaches. Here we investigated the population genetic structure of Gonyostomum semen, a bloom-forming phytoplankton species, across two continents. The species appears to be expanding in Europe, whereas similar trends are not observed in the USA. Our aim was to investigate if populations of Gonyostomum semen in Europe and in the USA are genetically differentiated, if there is population genetic structure within the continents, and what the potential drivers of differentiation are. To this end, we used a novel method based on single-amplified genomes combined with Restriction-site Associated DNA sequencing that allows de novo genotyping of natural single-cell isolates without the need for culturing. We amplified over 900 single-cell genomes from 25 lake populations across Europe and the USA and identified two distinct population clusters, one in Europe and another in the USA. Low genetic diversity in European populations supports the hypothesized recent expansion of Gonyostomum semen on this continent. Geographic population structure within each continent was associated with differences in environmental variables that may have led to ecological divergence of population clusters. Overall, our results show that single-amplified genomes combined with Restriction-site Associated DNA sequencing can be used to analyze microalgal population structure and differentiation based on single-cell isolates from natural, uncultured samples.
Democracy and Markets in a Partially Globalized World: Local and Global Financial Market Responses to Elections in Developing Countries
Authors: Cunha Raphael 
Published: March 2024

Abstract
Global market responses to elections are at the core of debates about financial globalization in developing countries. While existing research focuses on the ability of global markets to reward and punish national governments, much less is known about the role of domestic finance. I argue that domestic financial markets (1) react more strongly to elections than global markets due to excessive exposure to political risk at home and (2) lead global market responses to elections where domestic investors have an information advantage. I find support for these hypotheses using data on country fund pricing for major emerging markets between 1988 and 2015. The results show swifter and more dramatic reactions by domestic investors, which are transmitted to international markets. The findings underscore the underappreciated role of domestic investors in state-market relations under limited globalization.
Peribacillus frigoritoleransT7-IITJ, a potential biofertilizer, induces plant growth-promoting genes ofArabidopsis thaliana
Authors: Marik Debankona , Sharma Pinki , Chauhan Nar Singh , Jangir Neelam , Shekhawat Rajveer Singh , Verma Devanshu , Mukherjee Manasi , Abiala Moses , Roy Chandan , Yadav Pankaj , Sadhukhan Ayan 
Published: March 2024

AbstractAimsThis study aimed to isolate plant growth and drought tolerance-promoting bacteria from the nutrient-poor rhizosphere soil of Thar desert plants and unravel their molecular mechanisms of plant growth promotion.Methods and resultsAmong our rhizobacterial isolates, Enterobacter cloacae C1P-IITJ, Kalamiella piersonii J4-IITJ, and Peribacillus frigoritolerans T7-IITJ, significantly enhanced root and shoot growth (4˗5-fold) in Arabidopsis thaliana under PEG-induced drought stress. Whole genome sequencing and biochemical analyses of the non-pathogenic bacterium T7-IITJ revealed its plant growth-promoting traits, viz., solubilization of phosphate (40−73 µg/ml), iron (24 ± 0.58 mm halo on chrome azurol S media), and nitrate (1.58 ± 0.01 µg/ml nitrite), along with production of exopolysaccharides (125 ± 20 µg/ml) and auxin-like compounds (42.6 ± 0.05 µg/ml). Transcriptome analysis of A. thaliana inoculated with T7-IITJ and exposure to drought revealed the induction of 445 plant genes (log2fold-change &gt; 1, FDR &lt; 0.05) for photosynthesis, auxin and jasmonate signalling, nutrient uptake, redox homeostasis, and secondary metabolite biosynthesis pathways related to beneficial bacteria-plant interaction, but repression of 503 genes (log2fold-change &lt; −1) including many stress-responsive genes. T7-IITJ enhanced proline 2.5-fold, chlorophyll 2.5˗2.8-fold, iron 2-fold, phosphate 1.6-fold, and nitrogen 4-fold, and reduced reactive oxygen species 2˗4.7-fold in plant tissues under drought. T7-IITJ also improved the germination and seedling growth of Tephrosia purpurea, Triticum aestivum, and Setaria italica under drought and inhibited the growth of two plant pathogenic fungi, Fusarium oxysporum, and Rhizoctonia solani.ConclusionsP. frigoritolerans T7-IITJ is a potent biofertilizer that regulates plant genes to promote growth and drought tolerance.
Assessing the impact of transitioning to 11th revision of the International Classification of Diseases (ICD-11) on comorbidity indices
Authors: Nikiema Jean Noel , Thiam Djeneba , Bayani Azadeh , Ayotte Alexandre , Sourial Nadia , Bally Michèle 
Published: March 2024

Abstract

Objectives
This study aimed to support the implementation of the 11th Revision of the International Classification of Diseases (ICD-11). We used common comorbidity indices as a case study for proactively assessing the impact of transitioning to ICD-11 for mortality and morbidity statistics (ICD-11-MMS) on real-world data analyses.

Materials and Methods
Using the MIMIC IV database and a table of mappings between the clinical modification of previous versions of ICD and ICD-11-MMS, we assembled a population whose diagnosis can be represented in ICD-11-MMS. We assessed the impact of ICD version on cross-sectional analyses by comparing the populations’ distribution of Charlson and Elixhauser comorbidity indices (CCI, ECI) across different ICD versions, along with the adjustment in comorbidity weighting.

Results
We found that ICD versioning could lead to (1) alterations in the population distribution and (2) changes in the weight that can be assigned to a comorbidity category in a reweighting initiative. In addition, this study allowed the creation of the corresponding ICD-11-MMS codes list for each component of the CCI and the ECI.

Discussion
In common with the implementations of previous versions of ICD, implementation of ICD-11-MMS potentially hinders comparability of comorbidity burden on health outcomes in research and clinical settings.

Conclusion
Further research is essential to enhance ICD-11-MMS usability, while mitigating, after identification, its adverse effects on comparability of analyses.
Empirical Asset Pricing with Many Test Assets
Authors: Lönn Rasmus , Schotman Peter C 
Published: March 2024

Abstract
We formulate the problem of estimating risk prices in a stochastic discount factor (SDF) model as an instrumental variables regression. The IV estimator allows efficient estimation for models with non-traded factors and many test assets. Optimal instruments are constructed using a regularized sparse first stage regression. In a simulation study, the IV estimator is close to the infeasible GMM estimator in a setting with many assets. In an empirical application, the tracking portfolio for consumption growth appears strongly correlated with consumption news. It implies that consumption is a priced factor for the cross-section of excess equity returns. A similar regularized regression, projecting the SDF on test assets, leads to an estimate of the Hansen–Jagannathan distance, and identifies portfolios that maximally violate the pricing implications of the model.
Should Longtermists Recommend Hastening Extinction Rather Than Delaying It?
Authors: Pettigrew Richard 
Published: March 2024

Abstract
Longtermists argue we should devote much of our resources to raising the probability of a long happy future for sentient beings. But most interventions that raise that probability also raise the probability of a long miserable future, even if they raise the latter by a smaller amount. If we choose by maximising expected utility, this isn’t a problem; but, if we use a risk-averse decision rule, it is. I show that, with the same probabilities and utilities, a risk-averse decision theory tells us to hasten human extinction, not delay it. What’s more, I argue that morality requires us to use a risk-averse decision theory. I present this not as an argument for hastening extinction, but as a challenge to longtermism.
Existential Risk, Astronomical Waste, and the Reasonableness of a Pure Time Preference for Well-Being
Authors: Beard S J , Kaczmarek Patrick 
Published: March 2024

Abstract
In this paper, we argue that our moral concern for future well-being should reduce over time due to important practical considerations about how humans interact with spacetime. After surveying several of these considerations (around equality, special duties, existential contingency, and overlapping moral concern) we develop a set of core principles that can both explain their moral significance and highlight why this is inherently bound up with our relationship with spacetime. These relate to the equitable distribution of (1) moral concern in a universe that we can only causally affect in one temporal direction; (2) access to the benefits from using spacetime as a resource; and (3) the burdens of care given (1) and (2). We conclude by considering the practical implications of our argument and find that, while it is often assumed that a preference for present over future well-being weakens the case for existential risk mitigation, this likely is not the case.
TCP transcription factor StAST1 represses potato tuberization by regulating tuberigen complex activity
Authors: Sun Xiaomeng , Wang Enshuang , Yu Liu , Liu Shengxuan , Liu Tiantian , Qin Jun , Jiang Peng , He Shuangshuang , Cai Xingkui , Jing Shenglin , Song Botao 
Published: March 2024

Abstract
Potato (Solanum tuberosum L.) is cultivated worldwide for its underground tubers, which provide an important part of human nutrition and serve as a model system for belowground storage organ formation. Similar to flowering, stolon-expressed FLOWERING LOCUS T-like (FT-like) protein SELF-PRUNING 6A (StSP6A) plays an instrumental role in tuberization by binding to the bZIP transcription factors StABI5-like 1 (StABL1) and StFD-like 1 (StFDL1), causing transcriptional reprogramming at the stolon subapical apices. However, the molecular mechanism regulating the widely conserved FT-bZIP interactions remains largely unexplored. Here, we identified a TCP transcription factor StAST1 (StABL1 and StSP6A-associated TCP protein 1) binding to both StSP6A and StABL1. StAST1 is specifically expressed in the vascular tissue of leaves and developing stolons. Silencing of StAST1 leads to accelerated tuberization and a shortened life cycle. Molecular dissection reveals that the interaction of StAST1 with StSP6A and StABL1 attenuates the formation of the alternative tuberigen activation complex (aTAC). We also observed StAST1 directly activates the expression of potato GA 20-oxidase gene (StGA20ox1) to regulate GA responses. These results demonstrate StAST1 functions as a tuberization repressor by regulating plant hormone levels; our findings also suggest a mechanism by which the widely conserved FT-FD genetic module is fine-tuned.
Why do police consider leaving the profession?: The interplay between job demand stress, burnout, psychological distress, and commitment
Authors: Drew Jacqueline M , Sargeant Elise , Martin Sherri 
Published: March 2024

Abstract
Policing worldwide is facing a staffing and retention crisis. If the staffing exodus continues, communities will be left with too few police and large cohorts of inexperienced new recruits on the job. Drawing on 2,669 survey responses collected as part of a national study of law enforcement officers across the USA, we test an integrated theoretical model of the predictors of turnover intentions. We computed a path model using structural equation modelling, finding that job demand stressors (including trauma, organizational, and operational stressors), burnout, psychological distress, and commitment (including organizational commitment and occupational commitment) all play important roles in explaining the intentions of officers to exit the policing profession. Based on the study findings, the importance of trauma, organizational and operational job demand stress, and the differential impact of organizational and occupational commitment on police turnover intentions is established. Addressing burnout and psychological distress through a wellness agenda is likely to assist in stemming the outflow of officers from policing. The current study makes a significant empirical and practical contribution to the small body of existing police turnover research. The current research guides police leaders on the critical factors that must be considered when developing strategies and initiatives that aim to positively impact on the retention of officers within policing.
Safeguarding healthcare professionals from sexual harassment in the workplace: urgent need for effective training and education
Authors: Xiao Yu , Liu Liang , Zhang Zhou 
Published: March 2024

AbstractSexual harassment (SH) is a particularly harmful type of harassment that can inflict lasting psychological harm on victims. Within the healthcare sector, it negatively impacts teamwork, communication, and potentially compromises patient care. While concerns about workplace SH, including in healthcare, are long-standing, the #MeToo movement has brought renewed scrutiny to this issue since late 2017. Despite increased awareness, evidence suggests that SH remains prevalent in healthcare settings and shows no signs of decline over time. Therefore, there is an urgent need for effective training and intervention measures to enhance the identification of potential sexually offensive behaviors, thus fostering a work environment characterized by respect and inclusivity.
El Cuento del Destino: Latino Voters, Demographic Determinism, and the Myth of an Inevitable Democratic Party Majority
Authors: Corral Álvaro J , Leal David L 
Published: March 2024

Abstract
According to the “demography as destiny” theory, growing minority populations (which predominantly support Democrats) and the declining White population (which mostly votes Republican) will move politics and policy in more progressive directions. Latino voters are central to this account, but our critical analysis argues that such demographic determinism, which we call el cuento del destino, should be reconsidered. First, we argue that an overinvestment in the demography as destiny narrative causes distortions in party strategies; Democrats have been overconfident, and Republicans underconfident, about their abilities to secure the support of Latino voters. We examine trends in Latino voting behavior and partisan affiliation during and after the Trump years to show how the demographic narrative drives both parties to adopt suboptimal electoral strategies. Second, this narrative may also have implications for democracy itself, because misunderstandings about demographic determinism have led some Republicans to mistakenly worry that free and fair elections will inevitably lead to their party's electoral oblivion. Third, we interrogate the assumptions of the demography as destiny narrative, arguing that the political implications of Latino population growth are unclear and that the nature of Latino identity remains an open question. We conclude by describing the likely future of the Latino electorate as one characterized by growing partisan and political heterogeneity—including greater support for conservative politics—and suggest how the field of Latino politics might better understand such dynamics.
Humans in charge of trading robots: the first experiment
Authors: Asparouhova Elena , Bossaerts Peter , Cai Xiaoqin , Rotaru Kristian , Yadav Nitin , Yang Wenhao 
Published: March 2024

Abstract
We present results from an experiment where participants have access to automated trading algorithms, which they may deploy at will while still trading manually. Treatments differ in whether robots must not be halted, deployment is compulsory, or robots can be halted and replaced at will. We hypothesize that robot trading would reduce mispricing, and that the effect would be more pronounced as commitment degree increases. Yet, compared to manual trading only, we observe equally large and frequent mispricing and, in early trading, significantly higher bid–ask spreads and more frequent flash crashes/price surges. Participants earn more, provided they combine robot and manual trading. Compared to evidence from archival data, we find significantly higher use of liquidity-taking robots. We attribute this to the inability, in the field, to identify the presence of liquidity takers when they happen not to trade.