bluuebunny/crossref_metadata_2025_split huggingface dataset:
Harnessing the stream: algorithmic imaginary and coping strategies for live-streaming e-commerce entrepreneurs on Douyin
Authors: Wang Xinlu , Cao Shule 
Published: March 2024

AbstractWhen an algorithm is embedded into the platform economy as a digital infrastructure, it affects the visibility of information, the distribution of interests, and the labor process. In the context of live-streaming e-commerce, entrepreneurs interact with algorithms and consumers in real time to obtain more traffic. Compared with platform users, entrepreneurs are more sensitive to changes in the algorithm when facing great uncertainty in live-streaming and have become “algorithm experts”. This paper focuses on the short video platform Douyin and adopts the methods of field research and in-depth interviews. We interviewed 45 live commerce entrepreneurs and explored how entrepreneurs understand and interact with algorithms, particularly how their understanding of algorithms differs from that of users. By examining algorithmic imaginaries and coping practices, the authors hope to further the understanding of the relationships among labor, technology, and economic activity in new social contexts. In our study, we found that unlike platform users, who are often resilient, entrepreneurs have more active attitudes to learn about and interact with algorithms. They use words such as “admission tickets” and “like the wind” to describe algorithms. Unlike content creators, entrepreneurs’ understanding of arithmetic is influenced by the logic of traditional trade business when faced with traffic uncertainty. To seek certainty from a blurry stream, they adapt the methods of farther learning, frequent algorithm tests, more sophisticated work division, and resignation to fate. This study enriches the research perspective in the field of STS from a social-economic perspective and discusses the impact of technology on individual movement in the context of e-commerce. At the same time, this study also explores the technological ideology behind precarious work, which reflects individuals’ expectations of social order.
Gastric inflammatory myofibroblastic tumor: a case report
Authors: Hattori Taku , Tanizawa Yutaka , Shimoda Tadakazu , Koseki Yusuke , Furukawa Kenichiro , Fujiya Keiichi , Aizawa Daisuke , Sugino Takashi , Terashima Masanori , Bando Etsuro 
Published: March 2024

Abstract
Background
Inflammatory myofibroblastic tumor (IMT) of the stomach is an uncommon mesenchymal neoplasm. We present a case of gastric submucosal tumor (SMT) where the final diagnosis was IMT.

Case presentation
A 69-year-old man presented with a 24-mm SMT on the posterior wall of the middle third of the stomach that was detected by screening upper gastrointestinal endoscopy. Abdominal contrast-enhanced computed tomography showed that the tumor was well-enhanced. Although endoscopic ultrasonography-guided biopsy was performed, the histological diagnosis was not confirmed preoperatively. Since the tumor was clinically suspected to be a gastrointestinal stromal tumor, we performed gastric wedge resection by laparoscopic–endoscopic cooperative surgery. Pathologically, proliferative spindle cells with a positive reaction for smooth muscle actin, negativity for c-kit, desmin, s-100, CD34, STAT-6, β-catenin and anaplastic lymphoma kinase 1 were identified. Hence, the tumor was finally diagnosed as an IMT originating from the stomach.

Conclusions
When an SMT of the stomach is identified, the possibility of gastric IMT should be considered.
Efficacy and safety of FDG-PET for determining target volume during intensity-modulated radiotherapy for head and neck cancer involving the oral level
Authors: Kosugi Yasuo , Sasai Keisuke , Murakami Naoya , Karino Tatsuki , Muramoto Yoichi , Kawamoto Terufumi , Oshima Masaki , Okonogi Noriyuki , Takatsu Jun , Iijima Kotaro , Karube Shuhei , Isobe Akira , Hara Naoya , Fujimaki Mitsuhisa , Ohba Shinichi , Matsumoto Fumihiko , Murakami Koji , Shikama Naoto 
Published: March 2024

Abstract
Purpose
To determine the efficacy and safety of target volume determination by 18F-fluorodeoxyglucose positron emission tomography-computed tomography (PET-CT) for intensity-modulated radiation therapy (IMRT) for locally advanced head and neck squamous cell carcinoma (HNSCC) extending into the oral cavity or oropharynx.

Methods
We prospectively treated 10 consecutive consenting patients with HNSCC using IMRT, with target volumes determined by PET-CT. Gross tumor volume (GTV) and clinical target volume (CTV) at the oral level were determined by two radiation oncologists for CT, magnetic resonance imaging (MRI), and PET-CT. Differences in target volume (GTVPET, GTVCT, GTVMRI, CTVPET, CTVCT, and CTVMRI) for each modality and the interobserver variability of the target volume were evaluated using the Dice similarity coefficient and Hausdorff distance. Clinical outcomes, including acute adverse events (AEs) and local control were evaluated.

Results
The mean GTV was smallest for GTVPET, followed by GTVCT and GTVMRI. There was a significant difference between GTVPET and GTVMRI, but not between the other two groups. The interobserver variability of target volume with PET-CT was significantly less than that with CT or MRI for GTV and tended to be less for CTV, but there was no significant difference in CTV between the modalities. Grade ≤ 3 acute dermatitis, mucositis, and dysphagia occurred in 55%, 88%, and 22% of patients, respectively, but no grade 4 AEs were observed. There was no local recurrence at the oral level after a median follow-up period of 37 months (range, 15–55 months).

Conclusions
The results suggest that the target volume determined by PET-CT could safely reduce GTV size and interobserver variability in patients with locally advanced HNSCC extending into the oral cavity or oropharynx undergoing IMRT.
Trial registration
UMIN, UMIN000033007. Registered 16 jun 2018, https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000037631
Rendezvous-PIERCE technique: establishing a channel through severe calcification in infrainguinal arterial lesions using needle rendezvous
Authors: Haraguchi Takuya , Tsujimoto Masanaga , Kashima Yoshifumi , Sato Katsuhiko , Fujita Tsutomu 
Published: March 2024

Abstract
Background
Severe calcification often prevents device passage and balloon expansion in cases of lower extremity artery disease. To address this limitation, we introduced a novel calcium modification technique called Rendezvous-PIERCE (R-PIERCE).

Methods
A needle was inserted in a retrograde manner and advanced to touch the tip of an antegrade guidewire within the lesion. Then, the guidewire was advanced into the lumen of the needle to achieve partial guidewire externalization, also known as needle rendezvous. The needle was then introduced over the externalized guidewire under wire tension and repeatedly rotated and advanced across the lesion to modify calcified intimal plaques. Notably, this technique can be applied in the opposite direction.

Results
Case 1 involved a 68-year-old male with a calcified occlusion of the anterior tibial artery. An antegrade guidewire reached the midpoint of the occlusion; however, microcatheters and balloons could not pass through the proximal calcification. Therefore, R-PIERCE was used to modify uncrossable lesions. An antegrade 2.5-mm balloon crossed and dilated the lesion, achieving hemostasis at the needle insertion site. The antegrade guidewire successfully crossed the entire lesion and was dilated by the 2.5-mm balloon. Final angiography demonstrated successful flow. In Case 2, an 80-year-old male had a calcified femoropopliteal occlusion. An antegrade guidewire was advanced into the distal superficial femoral artery (SFA); however, no device could follow it. R-PIERCE was performed to modify the calcification from the distal to the medial SFA. The antegrade balloon successfully crossed and dilated obstructed lesions. Furthermore, the antegrade guidewire crossed the entire lesion, and the antegrade balloon was dilated. Final angiography revealed a successful flow without complications.

Conclusions
R-PIERCE is useful for modifying complex calcified lesions during the wiring of occlusive lesions.
Spatial and temporal patterns and driving factors of forest fires based on an optimal parameter-based geographic detector in the Panxi region, Southwest China
Authors: Liu Jia , Wang Yukuan , Guo Haiyan , Lu Yafeng , Xu Yuanxin , Sun Yu , Gan Weiwei , Sun Rui , Li Zhengyang 
Published: March 2024

Abstract
Background
The Panxi region in China is among the areas that are most severely impacted by forest fires. Despite this, there is currently a lack of comprehensive and systematic research on the spatial and temporal distribution patterns, as well as the drivers, of forest fires in the region. To reveal bio-geo-climatic and anthropogenic influences, this study investigated the temporal and spatial characteristics of forest fires and migration patterns of the center of gravity of forest fires in Panxi. A parametric optimal geographical detection model was utilized to quantify the influence of various individual factors and their combinations on the spatial patterns of forest fire occurrence in the whole Panxi region and sub-region, by analyzing the forest fire dataset from 2004 to 2020.

Results
From 2004 to 2020, the Panxi region experienced an upward trend in the number of forest fires and the area burned. However, the trends were not consistent over the entire period. Between 2004 and 2014, both the number of fires and the area burned showed fluctuations and an overall increase. In contrast, between 2015 and 2020, there was a significant decrease in the number of fires, while the area burned showed a continued upward trend. The study identified abrupt changes in the frequency of forest fires and burned areas, primarily in 2007 and 2016. Spatially, forest fires in Panxi exhibited a positive correlation and local clustering. The river valley basin and hilly regions displayed a higher incidence of forest fires, which were concentrated mainly along the hill edges. In the whole area of Panxi, climatic factors have a predominant influence on forest fire occurrences. Specifically, evaporation, maximum temperature, average temperature, number of days without rain, and minimum temperature demonstrated the strongest explanatory power. Furthermore, this relationship was found to be reinforced when combined with topographical, human activities, and vegetation factors. The spatial variation of drought within each sub-district has a stronger explanatory power for the distribution characteristics of forest fires in the region than at the Panxi-wide scale. The factor with the maximum interaction in most regions was the dual factor of rainfall and drought.

Conclusions
The study’s findings validate the applicability of geographic probes for identifying the drivers of fire occurrence and enhance our understanding of the drivers and their combined effects on the spatial context of the fire-incident study area.
Assessment of serum interleukin 6 in a sample of Egyptian patients with schizophrenia
Authors: Ella Eman Ibrahim Abo El , Rabie Eman S. , Sheikh Mona Mahmoud El , Ghamry Reem Hassan El , Hotar Mostafa Salah , Gabrielle Fiby Fayez 
Published: March 2024

Abstract
Background
Inflammation has been demonstrated to play a pathophysiological function in schizophrenia. Raised interleukin-6 (IL-6) levels have been the most consistently linked to schizophrenia. It was hypothesized that IL-6 contributed to the development of both adverse and beneficial symptoms.
The aim of the study was to estimate the level of serum IL-6 in patients with schizophrenia and its relation to positive in addition to negative symptoms.

Patient and methods
This case–control descriptive cross-sectional study was conducted on 40 patients, divided into two groups: 20 individuals in Group A (patients group) were treatment-naive for their first episode of schizophrenia, and 20 volunteers in Group B (control group) were matched for gender and age to the patient group. Both groups were evaluated for their serum interleukin-6 levels using the ELISA method. Patients and controls were recruited from the Okasha Institute of Psychiatry, Faculty of Medicine, and Ain Shams University Hospitals.

Results
Cases with schizophrenia who were experiencing their first episode and had not yet begun any form of therapy had a considerably higher mean serum IL-6 level compared to the healthy control group.

Conclusion
The level of serum interleukin 6 in first-episode treatment-naïve individuals with schizophrenia is higher than that of healthy controls, revealing a probable underlying immunological pathology. However, serum interleukin-6 levels were not significantly correlated with positive, negative, or general psychopathology symptoms.
Economic evaluations performed alongside randomized implementation trials in clinical settings: a systematic review
Authors: Carrandi Alayna , Grove Amy , Skouteris Helen , Melder Angela , Hu Yanan , Dever Michelle , Higgins Alisa 
Published: March 2024

Abstract
Background
Economic evaluations alongside implementation trials compare the outcomes and costs of competing implementation strategies to identify the most efficient strategies. The aims of this systematic review were to investigate how economic evaluations are performed in randomized implementation trials in clinical settings and to assess the quality of these evaluations.

Methods
A systematic literature review was conducted on 23 March 2023 to identify studies that reported on economic evaluations embedded in randomized implementation trials in clinical settings. A systematic search was applied across seven databases, and references of relevant reviews were screened for additional studies. The Drummond Checklist was used to assess the quality and risk of bias of included economic evaluations. Study characteristics and quality assessments were tabulated and described.

Results
Of the 6,550 studies screened for eligibility, 10 met the inclusion criteria. Included studies were published between 1990 and 2022 and from North America, the United Kingdom, Europe, and Africa. Most studies were conducted in the primary and out-patient care setting. Implementation costs included materials, staffing, and training, and the most common approach to collecting implementation costs was obtaining expense and budget reports. Included studies scored medium to high in terms of economic methodological quality.

Conclusions
Economic evidence is particularly useful for healthcare funders and service providers to inform the prioritization of implementation efforts in the context of limited resources and competing demands. The relatively small number of studies identified may be due to lack of guidance on how to conduct economic evaluations alongside implementation trials and the lack of standardized terminology used to describe implementation strategies in clinical research. We discuss these methodological gaps and present recommendations for embedding economic evaluations in implementation trials. First, reporting implementation strategies used in clinical trials and aligning these strategies with implementation outcomes and costs are an important advancement in clinical research. Second, economic evaluations of implementation trials should follow guidelines for standard clinical trial economic evaluations and adopt an appropriate costing and data collection approach. Third, hybrid trial designs are recommended to generate evidence for effective and cost-effective implementation strategies alongside clinical effectiveness and cost-effectiveness.

Trial registration
The review was prospectively registered with PROSPERO (CRD42023410186).
Anti-cancer activity of Moringa oleifera Lam. seed oil on oral cancer
Authors: Das Moumita , Mohanty Jatindra Nath , Bhuyan Sanat Kumar , Bhuyan Ruchi 
Published: March 2024

Abstract
Background
Despite recent advances in the diagnosis and treatment of oral cancer, relative survival rates have not changed significantly. Moringa oleifera (M. oleifera) Lam. is one such plant with its anticancer properties being proved in its leaves, stem, flowers but no studies are yet reported proving the anticancer property of its seed oil on oral cancer. This study aimed to evaluate the anti-proliferative and cytotoxic effect of M. oleifera seed oil against two Oral squamous cell carcinoma cell lines CAL27 and SCC15 using MTT assay.

Results
2D GC-TOF Mass spectrometry revealed a total of 199 compounds, among which the majority were alkanes (68.2016%) and fatty acid esters (11.1399%). The MTT assay report showed good dose-dependent activity. A significant reduction in cell viability within 24 h with IC50 value of 17.78 µg/mL and 24.28 µg/mL for all treatment groups was observed for both the cell lines CAL27 and SCC15.

Conclusion
MTT assay showed a significant decrease in cell viability with an increase in the oil dose, thereby revealing the cytotoxic and anti-proliferative activity of M. oleifera seed oil on oral cancer cell lines namely CAL27and SCC15. The results of this study indicate that M. oleifera seed oil can be used as a potent anti-cancer agent in the treatment of Oral cancer.

Graphical abstract
Deep Vein Thrombosis as the Presenting Sign in an Adolescent With New-Onset Type 2 Diabetes
Authors: Cooper Felicia , Carakushansky Mauri , Johnson Craig M , Gurnurkar Shilpa 
Published: March 2024

Abstract
Prothrombin G20210A mutation occurs in only 2% to 3% of the population, but usually does not become apparent unless the individual exhibits another risk factor for clotting. A risk factor such as hyperglycemia in the setting of diabetes mellitus may accelerate this clotting process, even at a very young age. In this case report, we discuss a 15-year-old boy presenting with left calf swelling and pain, found to have extensive deep vein thrombosis in the setting of hyperglycemia and a newly discovered prothrombin G20210A mutation. Venous thromboembolism in the setting of type 2 diabetes mellitus has not been described in children.
104 Use of the eShunt Implant in Treatment of Aneurysmal Subarachnoid Hemorrhage Communicating Hydrocephalus
Authors: Lylyk Pedro , Lylyk Ivan , Bleise Carlos , Scrivano Esteban , Lylyk Nicholas Pedro , Beneduce Brandon , Heilman Carl B. , Malek Adel M. 
Published: March 2024

INTRODUCTION:
Aneurysmal subarachnoid hemorrhage (aSAH) may cause communicating hydrocephalus and elevated intracranial pressure (ICP) not amenable to weaning of cerebrospinal fluid (CSF) external ventricular drainage (EVD), often requiring surgical ventriculoperitoneal shunting (VPS) with risk of hemorrhage and infection.

METHODS:
Patients having intractable elevated ICP with EVD clamping and favorable inferior petrosal sinus and bony anatomy were included. ICP was monitored before and after eShunt deployment for 36-48 hours. Primary endpoint was reached if ICP remained <20 cmH2O enabling EVD removal. CT imaging of the brain was obtained immediately post-eShunt placement to evaluate eShunt placement and assess for any presence of new procedural hemorrhage.

RESULTS:
Seven out of eight patients (5 female; age 64 ± 12 years) underwent successful transfemoral transvenous eShunt procedure at 25.3 days (Range 14-38) post aSAH. Primary endpoint was achieved in all with EVD removal by 36-48 hours without procedural or delayed hemorrhage. Mean ICP rapidly decreased from 33.4 to 13 cmH2O at 1 hour (p < 0.0001) and to 9 cmH2O (p < 0.0001) at 36 hours post eShunt placement.

CONCLUSIONS:
These early encouraging results of the eShunt implant suggest clinical role and utility in the management of subarachnoid hemorrhage associated hydrocephalus possibly eschewing the need for VP shunt surgery and enabling minimally invasive CSF diversion in patients requiring dual anti-platelet or anticoagulant therapy.
1075 The Effect of Regional Procedural Preference on Outcomes After Posterior Decompression for Degenerative Cervical Myelopathy: Individual Participant Data Meta-Analysis of a Prospective, Multinational Dataset of 1047 Cases
Authors: Bak Alex Beomju , Moghaddamjou Ali , Arnold Paul M. , Harrop James S. , Fehlings Michael G. , Hachem Laureen D. 
Published: March 2024

INTRODUCTION:
There is considerable debate regarding the relative effectiveness of laminoplasty vs. laminectomy and fusion for posterior surgical decompression of degenerative cervical myelopathy (DCM).

METHODS:
Subjects with DCM that underwent posterior decompression was derived from three independent, prospective, multicentre clinical trials (CSM-NA, CSM-I, CSM-Protect). Primary endpoint was change in SF36-PCS (minimum clinically important difference [MCID] 4) at 1yr compared to pre-operative assessment. Secondary endpoints were change in mJOA (MCID 2) score, Neck Disability Index (NDI; MCID 15) score, NDI Pain Intensity score, and SF36-MCS (MCID 4) score. Two comparison cohorts were created: i) laminoplasty (LP) and ii) laminectomy and fusion (LF). One-stage hierarchical mixed-effects meta-analyses with study and treatment exposure as random effects were performed. As subgroup analysis, the influence of procedural volume between LP-predominant sites, LF-predominant sites, and volume-equivalent sites was investigated.

RESULTS:
From a total of 1047 patients with DCM, 369 patients met eligibility criteria. There was geographic variability in surgical choice with higher rates of laminectomy and fusion in Brazil and Canada and higher laminoplasty rates in Japan and India. USA had similar rates of LF and LP. When compared to LF-predominant sites, LP-predominant sites achieved greater rates of MCID for mJOA at 1yr (85.4% v. 68.7%, p=0.036) with their predominant technique. There were no significant differences in MCID rates of NDI, SF36-PCS, or SF36-MCS. When comparing LF-predominant and LP-predominant sites with USA, a volume equivalent site, there were no significant differences in MCID rates of all outcomes.

CONCLUSIONS:
Sites that primarily used LP achieved greater rate of MCID in mJOA with laminoplasty than laminectomy with fusion from primarily LF sites. This suggests that experience with either LP or LF can drive outcomes which has interesting healthcare delivery implications.