bluuebunny/crossref_metadata_2025_split huggingface dataset:
Gain‐saturated SOA‐based optical power booster for spectrum‐sliced incoherent light
Authors: Kim Tae‐Young , Kim Sun‐Jong , Park Chang‐Soo 
Published: September 2007

AbstractAn optical power booster based on a gain‐saturated semiconductor optical amplifier with an injected holding light is experimentally demonstrated for an optical access network using spectrum‐sliced incoherent light (SSIL). The results show that the proposed booster can provide not only a signal gain of 10.8 dB but also a Q‐factor of 8.9 for a 2.5 Gb/s SSIL signal, transmitted over 10 km of single‐mode fiber. The corresponding bit‐error rate is lowered to 6 × 10−11. © 2007 Wiley Periodicals, Inc. Microwave Opt Technol Lett 49: 3038–3040, 2007; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/mop.22966
A time‐domain extraction for the spice‐compatible models of power delivery networks in PCB
Authors: Kuo Chih‐Wen , Wang Chen‐Chao 
Published: September 2007

AbstractSimultaneous switch noise, or power/ground bounce noise, on the power and ground planes of high‐speed circuit packages is one of the main concerns of signal integrity or power integrity issues. A novel time‐domain approach is proposed to synthesize the broadband models of the resonance effect of power/ground planes. Either from measurements by time‐domain reflectrometry or simulations by the finite‐difference time‐domain method, the time‐domain step response of the planes is characterized with a pole‐residue representation obtained through the matrix pencil method. A new equivalent circuit models are then synthesized through the pole‐residue representations. The synthesized model can accurately predict the resonance behavior of power/ground planes over a wide frequency range. These models can be efficiently incorporated into the currently available circuit simulator such as HSPICE or Agilent ADS for the consideration of power/ground bouncing noise in high‐speed circuits. © 2007 Wiley Periodicals, Inc. Microwave Opt Technol Lett 49: 3001–3004, 2007; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/mop.22967
Active integrated antenna for mobile TV signal reception
Authors: Yoon Ick‐Jae , Balzovsky Evgeny , Buyanov Yuri , Park Se‐Hyun , Kim Youngeil , Koshelev Vladimir 
Published: September 2007

AbstractThis paper proposes a small‐sized field‐effect transistor (FET) based active integrated antenna (AIA) for terrestrial digital multimedia broadcasting (T‐DMB) signal reception, which is one of the mobile TV services allocated to 200 MHz band. The commercially used T‐DMB antenna is a 120 mm long monopole, but the size of the proposed one is reduced to 50 mm by the method of active device integration. The active device integrated to the radiator influences not only on the current distribution at the radiator but also the input impedance, results in an antenna size reduction with an enhanced gain. In addition to this, a band‐pass filter is designed at the input port of the radiator. This plays a role as a matching circuit between a radiator and an active device as well as provides a band‐selection function simultaneously to be free of other high intensity signals existing around the T‐DMB band. The antenna effective length related to the same‐sized monopole and noise figure are measured to verify the validity of the proposed antenna. The performance of the proposed FET based AIA shows the feasibility of designing absolutely small‐sized antenna with active devices integrated compared to an operating frequency band. © 2007 Wiley Periodicals, Inc. Microwave Opt Technol Lett 49: 2998–3001, 2007; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/mop.22968
Novel ′′buried‐on‐wall′′ 900 MHz cavity‐backed slot antenna with circular polarization
Authors: Shi Zhiguo , Ren Wang , Liu Haiwen , Chen Kangsheng 
Published: September 2007

AbstractWe propose a circularly polarized cavity‐backed slot (CBS) antenna which is composed of two symmetrically placed L‐shaped slots on a 150 × 100 mm2 ground plane (back side) and fed by a microstrip network on the opposite plane (front side). A metal cavity is placed at the back side to reduce the effect caused by the wall behind the antenna and enhance the radiation on the front side; in this way it is suitable to be “buried‐on‐wall.” Simulation results of the return loss, radiation patterns, axial ratios, and gain are presented. The antenna was fabricated on FR‐4 substrate and the measured return loss agrees well with the simulated one. © 2007 Wiley Periodicals, Inc. Microwave Opt Technol Lett 49: 3169–3172, 2007; Published online in Wiley InterScience (www.interscience.wiley.com).DOI 10.1002/mop.22969
New method of detecting lymphatic disease using microwaves
Authors: Lonappan Anil , Thomas Vinu , Bindu G. , Jacob Joe , Rajasekaran C. , Mathew K. T. 
Published: September 2007

AbstractLymphatic filariasis (LF) is the world's most disabling and disfiguring diseases affects the persons making incapacitated or disfigured. This article presents a new solution for the early detection of LF. In vitro blood analysis is made based on the dielectric properties at microwave frequencies using rectangular cavity perturbation technique at the S‐band with the different samples of blood obtained from healthy donors as well as from patients suffering from filariasis. It is noticed that an appreciably change in the dielectric properties of patient samples with the normal healthy samples and this measurements were in good agreement with clinical analysis. This measurement technique is simple and suggests a new novel alternative in‐vitro method of diagnosing LF using microwaves and is completely independent of time unlike the traditional method diagnosis. © 2007 Wiley Periodicals, Inc. Microwave Opt Technol Lett 49: 3166–3169, 2007; Published online in Wiley InterScience (www.interscience.wiley.com).DOI 10.1002/mop.22970
In‐line RF‐MEMS series switches for reconfigurable antenna applications
Authors: Jung Chang Won , Lee Byungje , De Flaviis Franco 
Published: September 2007

AbstractThe air bridged RF‐MEMS capacitive series switches in single pole single throw transmission lines for reconfigurable antenna applications are presented. The RF characteristics of capacitive series switches are analyzed, measured, and compared with microstripline and coplanar‐waveguide, which are generally used for transmission lines of MEMS reconfigurable circuits. RF‐MEMS series switches are fabricated in both transmission lines on a glass substrate (εr = 7.4 and tan δ = 0.001). The reconfigurable beam steering spiral antenna (fo = 11 GHz), which is monolithic integrated with RF‐MEMS capacitive series switches on the same glass substrate, is also presented as an example of the use of in‐line capacitive series switches. © 2007 Wiley Periodicals, Inc. Microwave Opt Technol Lett 49: 3130–3134, 2007; Published online in Wiley Inter‐Science (www.interscience.wiley.com). DOI 10.1002/mop.22971
Dual‐band circular polarization square patch antenna for GPS and DMB
Authors: Kim S. M. , Yoon K. S. , Yang W. G. 
Published: September 2007

AbstractWe designed and implemented a dual‐band square patch antenna with circular polarization for the reception of GPS and DMB. Resonant elements of 1.5‐ and 2.6‐GHz bands are entire square patch and inner square patch divided by slots, respectively. And impedance bandwidths (VSWR ≤ 2) are 61 MHz (3.84%) for 1.5‐GHz band and 138 MHz (5.15%) for 2.6‐GHz band. The implemented antenna has a good radiation pattern characteristic. © 2007 Wiley Periodicals, Inc. Microwave Opt Technol Lett 49: 2925–2926, 2007; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/mop.22972
The sensory bladder (1): An update on the different sensations described in the lower urinary tract and the physiological mechanisms behind them
Authors: Wyndaele Jean‐Jacques , De Wachter Stefan 
Published: September 2007

AbstractAimsTo give an update of the actual information on sensory function in the lower urinary tract (LUT).MethodsWe give an up‐to‐date review of the most modern and reasonable approach to the topic of physiological mechanisms involved in LUT sensory function and different sensations described in the LUT.ResultsAlthough the sensory function of the LUT is a main player in the function of continence and micturition, it has been dealt with rather superficially for many decades. More recently the interest in this function grows and does so rapidly, both in basic as in clinical research. Sensation depends on neurophysiologic mechanisms in several different nerves, receptors, and transmitters. This knowledge creates a better understanding of sensory symptoms. Different stimuli can elicit sensations in the LUT such as bladder filling, micturition, noxious stimuli, external stimuli.ConclusionSensation is the prerequisite of conscious bladder control and deserves full attention in the management of LUT dysfunction. Neurourol. Urodynam. 27:274–278, 2008. © 2007 Wiley‐Liss, Inc.
What you should know about the vehicle routing problem
Authors: Laporte Gilbert 
Published: September 2007

AbstractIn the Vehicle Routing Problem (VRP), the aim is to design a set of m minimum cost vehicle routes through n customer locations, so that each route starts and ends at a common location and some side constraints are satisfied. Common applications arise in newspaper and food delivery, and in milk collection. This article summarizes the main known results for the classical VRP in which only vehicle capacity constraints are present. The article is structured around three main headings: exact algorithms, classical heuristics, and metaheuristics. © 2007 Wiley Periodicals, Inc. Naval Research Logistics, 2007
Robust estimation of the normal to a curve using optimal control
Authors: Fehrenbach J. , Hassine M. , Siala L. 
Published: September 2007

AbstractWe propose an optimal control problem whose optimal command approximates the normal vector field to a given curve. This problem is obtained by studying a partial differential equation satisfied by a map that jumps across the given curve. The gradient of the cost function is then estimated by an adjoint method, and an explicit algorithm is proposed to obtain the optimal command. Examples show that this numerical estimation of the normal is robust, in the sense that when the curve is not a simple closed curve, or when it is incomplete (dashed), the solution is still a good approximation of the normal. As applications, we show how the optimal state can help closing discontinuous curves and improve image restoration; it also provides a coloring of simple planar maps. Copyright © 2007 John Wiley & Sons, Ltd.
Clozapine‐related agranulocytosis associated with fever of unknown origin, protective hospitalisation, and multiple adverse events related to the administration of empiric antimicrobial treatment
Authors: Manfredi Roberto , Sabbatani Sergio 
Published: September 2007

AbstractAn exemplary case report of a patient who developed an unpredictable sudden, late‐onset clozapine‐related life‐threatening agranulocytosis expressed by a nadir of 14 polymorphonuclear cells/µL, and subsequently underwent protective hospitalisation and broad spectrum, empiric antimicrobial therapy and also experienced serious intolerance to a number of administered antibiotic and antifungal agents, is reported and discussed on the grounds of the available evidence from the literature. Copyright © 2007 John Wiley & Sons, Ltd.
How to distinguish healthy from diseased? Classification strategy for mass spectrometry‐based clinical proteomics
Authors: Hendriks Margriet M. W. B. , Smit Suzanne , Akkermans Wies L. M. W. , Reijmers Theo H. , Eilers Paul H. C. , Hoefsloot Huub C. J. , Rubingh Carina M. , de Koster Chris G. , Aerts Johannes M. , Smilde Age K. 
Published: September 2007

AbstractSELDI‐TOF‐MS is rapidly gaining popularity as a screening tool for clinical applications of proteomics. Application of adequate statistical techniques in all the stages from measurement to information is obligatory. One of the statistical methods often used in proteomics is classification: the assignment of subjects to discrete categories, for example healthy or diseased. Lately, many new classification methods have been developed, often specifically for the analysis of X‐omics data. For proteomics studies a good strategy for evaluating classification results is of prime importance, because usually the number of objects will be small and it would be wasteful to set aside part of these as a ‘mere’ test set. The present paper offers such a strategy in the form of a protocol which can be used for choosing among different statistical classification methods and obtaining figures of merit of their performance. This paper also illustrates the usefulness of proteomics in a clinical setting, serum samples from Gaucher disease patients, when used in combination with an appropriate classification method.
Retraction: Identification of new high mobility group A1 associated proteins
Authors: Pierantoni Giovanna Maria , Esposito Francesco , Giraud Stéphane , Bienvenut Willy Vincent , Diaz Jean Jacques , Fusco Alfredo 
Published: September 2007

AbstractThe above article from Proteomics, published online on 19 September 2007 in Wiley Online Library (http://onlinelibrary.wiley.com/doi/10.1002/pmic.200700148/pdf) and in Volume 7, No. 20, pp. 3735–3742, has been retracted by agreement between some of the authors (S. Giraud, W. V. Bienvenut, J. J. Diaz), the Editor‐in‐Chief and Wiley‐VCH GmbH & Co. KGaA. The retraction has been agreed due to concerns in relation to Figure 2C. Multiple HMGA1‐pulldown bands in the immunoblot images (upper panel) appear to have been duplicated. In addition, the Coomassie gel bands of Figure 2C (lower panel) appear to have also been duplicated. The authors are unable to provide the original source files that were used to generate these data. While the authors maintain that these findings were confirmed in replicate experiments, the Editorial Board of Proteomics has decided to retract the paper. No issues have been raised with regard to any of the other data in this manuscript. The remaining authors (G. M. Pierantoni, F. Esposito, A. Fusco) have not agreed to the retraction.
8‐Plex quantitation of changes in cerebrospinal fluid protein expression in subjects undergoing intravenous immunoglobulin treatment for Alzheimer's disease
Authors: Choe Leila , D'Ascenzo Mark , Relkin Norman R. , Pappin Darryl , Ross Philip , Williamson Brian , Guertin Steven , Pribil Patrick , Lee Kelvin H. 
Published: September 2007

AbstractAn 8‐plex version of an isobaric reagent for the quantitation of proteins using shotgun methods is presented. The 8‐plex version of the reagent relies on amine‐labeling chemistry of peptides similar to 4‐plex reagents. MS/MS reporter ions at 113, 114, 115, 116, 117, 118, 119, and 121 m/z are used to quantify protein expression. This technology which was first applied to a test mixture consisting of eight proteins and resulted in accurate quantitation, has the potential to increase throughput of analysis for quantitative shotgun proteomics experiments when compared to 2‐ and 4‐plex methods. The technology was subsequently applied to a longitudinal study of cerebrospinal fluid (CSF) proteins from subjects undergoing intravenous Ig treatment for Alzheimer's disease. Results from this study identify a number of protein expression changes that occur in CSF after 3 and 6 months of treatment compared to a baseline and compared to a drug washout period. A visualization tool was developed for this dataset and is presented. The tool can aid in the identification of key peptides and measurements. One conclusion aided by the visualization tool is that there are differences in considering peptide‐based observations versus protein‐based observations from quantitative shotgun proteomics studies.
Differential analysis of Bacillus anthracis after pX01 plasmid curing and comprehensive data on Bacillus anthracis infection in macrophages and glial cells
Authors: Park Sung‐Ha , Oh Hee‐Bok , Seong Won‐Keun , Kim Chan‐Wha , Cho Sang‐Yun , Yoo Cheon‐Kwon 
Published: September 2007

AbstractBacillus anthracis is a gram‐positive bacterial organism responsible for anthrax. This organism has two pathogenic plasmids: pX01 and pX02. The genetic function of pX01, which comprises about 198 kb, is not known, except for a region called the pathogenic island, which contains three genes—pag, lef, and cya—that code for three toxic proteins. A 2‐D difference gel electrophoresis (2‐D DIGE) system was used to verify the existence of proteins controlled by the pX01 plasmid, and protein regulation data were obtained using DeCyder software. A total of 1728 proteins were identified in the wild‐type strain of this organism and 1684 in the pX01 plasmid. Twenty‐seven of these proteins disappeared and eight appeared when the pX01 plasmid was removed. An additional 52 proteins were downregulated and 15 were upregulated when this plasmid was removed. A total of 102 proteins have been identified using the MALDI‐TOF method of analysis, including 49 whose functions are unknown. Among these, 31 participate in metabolic processes, two in cellular processes, 15 in the processing of genetic information, and five in the processing of extracellular information. Another seven proteins participate in bacterial virulence and pathogenesis. We investigated the functions of these proteins in other bacteria, particularly the B. anthracis derivative H9041. Bacterial growth differed between pX01+/pX02+ B. anthracis and its pX01–/pX02+ derivative as did the cytotoxicity of macrophages infected by pX01+/pX02+ B. anthracis and the pX01–pX02+ derivative. We also found that S100B protein levels increased in the host infected with pX01+/pX02+ B. anthracis or its pX01–/pX02+ derivative. These data suggest that the pX01 plasmid plays a key role in the regulation of protein functions in B. anthracis.
Proteomic analysis of calcium‐dependent secretion in Toxoplasma gondii
Authors: Kawase Osamu , Nishikawa Yoshifumi , Bannai Hiroshi , Zhang Houshuang , Zhang Guohong , Jin Shigeki , Lee Eung‐Goo , Xuan Xuenan 
Published: September 2007

AbstractToxoplasma gondii is an intracellular protozoan parasite that invades a wide range of nucleated cells. In the course of intracellular parasitism, the parasite releases a large variety of proteins from three secretory organelles, namely, micronemes, rhoptries and dense granules. Elevation of intracellular Ca2+ in the parasite causes microneme discharge, and microneme secretion is essential for the invasion. In this study, we performed a proteomic analysis of the Ca2+‐dependent secretion to evaluate the protein repertoire. We found that Ca2+‐mobilising agents, such as thapsigargin, NH4Cl, ethanol and a Ca2+ ionophore, A23187, promoted the secretion of the parasite proteins. The proteins, artificially secreted by A23187, were used in a comparative proteomic analysis by 2‐DE followed by PMF analysis and/or N‐terminal sequencing. Major known microneme proteins (MICs), such as MIC2, MIC4, MIC6 and MIC10 and apical membrane antigen 1 (AMA1), were identified, indicating that the proteomic analysis worked accurately. Interestingly, new members of secretory proteins, namely rhoptry protein 9 (ROP9) and Toxoplasma SPATR (TgSPATR), which was a homologue of a Plasmodium secreted protein with an altered thrombospondin repeat (SPATR), were detected in Ca2+‐dependent secretion. Thus, we succeeded in detecting Ca2+‐dependent secretory proteins in T. gondii, which contained novel secretory proteins.
Pre‐transplant depression as risk factor for survival of patients undergoing allogeneic haematopoietic stem cell transplantation
Authors: Grulke Norbert , Larbig Wolfgang , Kächele Horst , Bailer Harald 
Published: September 2007

AbstractIntroduction: Depression is discussed as a possible risk factor for survival in cancer patients. We explored this relationship for patients undergoing allogeneic haematopoietic stem cell transplantation (HSCT).Patients and methods: The depression subscale of the Hospital Anxiety and Depression Scale (HADS) served as a measure for depression. One hundred and thirty‐eight patients (mean age 41 years; different diagnoses) participating in a psycho‐oncology study filled in the HADS after admission for allogeneic HSCT. They were followed‐up for at least two years; 72 patients died during follow‐up.Results: Depression scores were not correlated with medical and psychosocial objective factors with the exception of having under‐aged children. Controlling for medical factors that showed up as predictors for survival in our sample (patient's age at HSCT, having had a transplant before, risk for treatment failure) the HADS depression score (range 0–21) emerged as an independent predictor (Cox regression): hazard ratio = 1.087, 95% CI = 1.018–1.161.Conclusion: Depression is probably not a simple indicator of a worse health status. Further research is needed to decide if depression must be considered as an independent risk factor for survival when diagnosed in the pre‐transplant period. Copyright © 2007 John Wiley & Sons, Ltd.
Employing the treatment‐free interval of intermittent androgen ablation to screen candidate prostate cancer therapies
Authors: Mao Shifeng , Daliani Danai D. , Wang Xuemei , Thall Peter F. , Do Kim‐Anh , Perez Cherie A. , Brown Melissa A. , Bouchillon Kathleen , Carter Cindy M. , Logothetis Christopher J. , Kim Jeri 
Published: September 2007

AbstractBACKGROUNDBecause neither continuous nor intermittent hormonal therapy is curative, we designed a clinical model to screen new drugs for additive or synergistic effects with hormonal therapy and used IM862, a naturally occurring dipeptide with antiangiogenic and immunomodulatory properties, to test it.METHODSPatients with prostate cancer who had rising PSA levels after radical prostatectomy and/or radiation therapy were given combined androgen ablation for 3 months. After 2 months' treatment, patients were randomly assigned in a double‐blind fashion to receive intranasal IM862 or placebo daily. Treatment continued for 6 months or until disease progression, which was defined by a rising serum PSA level, the appearance of new skeletal or extraskeletal metastatic disease, or new symptoms requiring intervention.RESULTSSeventy‐one patients were evaluable for response. Median time to PSA progression was not reached in either group. At 6 months, disease had progressed in 14 (41%) of the 34 patients receiving treatment and 18 (49%) of the 37 receiving placebo (P = 0.39). No significant toxicities emerged.CONCLUSIONSThe model was demonstrated to be an efficient platform for new drug screening; however, IM862, though well tolerated, failed to demonstrate superiority over placebo in prolonging time to PSA progression. Prostate 67: 1677–1685, 2007. © 2007 Wiley‐Liss, Inc.