bluuebunny/crossref_metadata_2025_split huggingface dataset:
Normal mineralization patterns of laryngeal cartilage on computed tomography and their implication for laryngeal and hypopharyngeal cancer management: A cross-sectional retrospective analysis
Authors: Sable Nilesh , Kshirsagar Rupali , Shukla Shreya , Thakur Meenakshi , Mahajan Abhishek 
Published: March 2024

ABSTRACT

Background:
A common problem faced during the evaluation of computed tomography (CT) scan in a patient with laryngeal and hypopharyngeal carcinoma is deciding whether the changes in the laryngeal cartilage are due to tumor involvement, reactive changes, or simply a normal variation.

Objectives:
We aimed to characterize the variation in the distribution and sex predilection of laryngeal cartilage mineralization in a cohort of patients without malignancy to establish its significance in patients with laryngeal/hypopharyngeal cancer.

Materials and Methods:
This cross-sectional study was conducted between May 2016 and December 2017 in the Department of Radiodiagnosis at the Tata Memorial Hospital, Mumbai, India. We enrolled 185 patients with head-and-neck cancer (other than laryngeal/hypopharyngeal primaries) aged between 20 and 79 years who had undergone a CT neck as a part of their diagnostic workup. Specialist radiologists determined the total, symmetric, and asymmetric mineralization frequencies of the laryngeal cartilages. Mineralization was graded as sclerosis, ossification, and calcification.

Results:
Asymmetric mineralization of the thyroid, cricoid, and arytenoid cartilages were seen in 82 (44.3%), 29 (15.7%), and 39 (21.1%), respectively, of our study population. Asymmetric thyroid, cricoid, and arytenoid sclerosis were seen in 32 (17.3%), 3 (1.6%), and 14 (7.6%), respectively, of the study population. Asymmetric arytenoid sclerosis was more common on the left side (8 [4.3%]; all 8 noted in men) than on the right (6 [3.2%], 4 in men, and 2 in women).

Conclusion:
Though sclerosis of ossified portions of the cartilage is an early sign of cartilage invasion by laryngeal and hypopharyngeal carcinoma, some of the sclerotic cartilage may represent a normal variation. These and other common variations in mineralization patterns should be considered when evaluating CT scans of patients with laryngeal and hypopharyngeal cancer for cartilage invasion to avoid false-positive observations.
Psychocutaneous Disorders in Paediatric Population: A Cross-Sectional Observational Study in a Tertiary Care Centre in Eastern India
Authors: Mohapatra Liza , Nayak Surajit , Dixit Nibedita , Nayak Manoj Kumar 
Published: March 2024

Abstract

Introduction:
Psychocutaneous disorders in children have been a gray zone in dermatology practice. It can be secondary to some primary dermatological disorder or can be a presentation of underlying primary psychiatric illness. There is a paucity of data regarding the occurrence of these disorders in the pediatric population. The present study was carried out to assess the proportion of primary psychiatric dermatoses in the pediatric population seeking dermatological care.

Materials and Methods:
This was a hospital-based cross-sectional observational study done over 6 months. All consecutive children <14 years old presenting with primary psychiatric disorders (PPDs) to the dermatology outpatient department were recruited in the study.

Results:
PPDs were found in 0.41% of the pediatric patients attending the outpatient department. Dermatitis artefacta was the most common PPD in our study (47.05%). Other less frequently observed PPDs were trichotillomania, lip-licking dermatitis, and nail-biting. Underlying psychiatric illness was found in 41.17% of affected children.

Conclusion:
Primary psychiatric dermatoses in children could go undiagnosed because of its rarity but early diagnosis is essential as it can be an early sign or a harbinger of underlying severe psychiatric illness.
Clinicoepidemiological Spectrum of Connective Tissue Diseases in the Pediatric Population in a Tertiary Care Center in North India: A Cross-sectional Observational Study
Authors: Senapati Dharitree , Mendiratta Vibhu , Maheshwari Anu , Yadav Vidya , Garg Taru , Ahmed Yusufa 
Published: March 2024

Abstract

Background:
Connective tissue diseases (CTDs) are chronic in nature and carry a high risk of morbidity, disability, and mortality if not recognized and treated promptly. Data on clinical spectrum of CTDs in the pediatric age group are sparse from developing countries such as India.

Objective:
To study the clinicoepidemiological spectrum of CTDs in the pediatric age group.

Methodology:
A hospital-based, cross-sectional, observational study was undertaken over a period of 16 months from January 2021 to June 2022 in the dermatology outpatient department and pediatric rheumatology clinic in a tertiary care hospital in North India. Clinical and laboratory findings were recorded.

Results:
A total of 100 children diagnosed with a CTD were included in the study. The mean age was 11.11 ± 4.20 years. Out of 100 children, 55% were female and 45% were male with a male-to-female ratio of 1:1.2. Our study included 63% juvenile idiopathic arthritis, 17% systemic lupus erythematosus, 7% juvenile dermatomyositis, 6% Kawasaki disease, 3% systemic sclerosis, and 2% Henoch–Schonlein purpura and mixed CTD patients each. Mucocutaneous features commonly seen were rash (40%), oral ulcers (22%), and photosensitivity (18%). Commonly seen systemic features were joint pain (77%), followed by fever (63%).

Conclusion:
Mucocutaneous manifestations are frequently seen in CTDs and constitute a frequent and an early manifestation of CTD. Early recognition of CTD in the pediatric age group will help in timely initiation of treatment to prevent disabilities and mortality.
Comparison of ultrasound-guided erector spinae plane block versus transmuscular quadratus lumborum block for postoperative analgesia after caesarean delivery: A prospective randomized non-inferiority clinical trial
Authors: Joshi Reesha , Jeevan Ram , Amutha Selvaraju V. , Ramakrishnan Lakshmi , Natarajan Naveen Ramji 
Published: March 2024

AbstractBackground and Aims:Regional techniques are a part of multimodal analgesia following cesarean delivery. Cesarean delivery warrants a regional technique, which can provide somatic and visceral analgesia-like quadratus lumborum block (QLB) and erector spinae plane block (ESPB). In this study, we investigated the non-inferiority of ESPB at T12 and transmuscular-QLB (TQLB) at L2-L3 for postoperative analgesia in cesarean delivery.Material and Methods:In this prospective, randomized, non-inferiority trial, 124 patients undergoing cesarean delivery were enrolled to receive bilateral TQLB or ESPB with 20 mL of 0.25% ropivacaine on each side. All patients received prophylactic acetaminophen and ketorolac for 2 days. Our primary objective was to compare the total tramadol consumption in the first 48 h between the two groups. Secondary objectives were to compare cumulative tramadol consumption, postoperative Numeric Rating Scale (NRS) score at rest, and with movement at various time points, the time for first rescue analgesic requirement, development of complications related to the block, and patient satisfaction with analgesia between the two groups.Results:The total tramadol consumption in 48 h (47.3 ± 34.9 mg in ESPB and 50.9 ± 38.7 mg in TQLB), duration of first rescue analgesic (22.8 ± 15.8 h in ESPB and 22.7 ± 15.6 h in TQLB), and patient satisfaction were similar between the two groups. Both groups had similar pain scores except at rest at 6 h and on movement at 4 h, 6 h, and 36 h, whereas the ESPB group had lower NRS scores (P< 0.05).Conclusion:The analgesic effect of bilateral ESPB at T12 was non-inferior to that of bilateral TQLB post-caesarean delivery.
Comparison of anterior, posterior, and lateral approaches of ultrasound-guided quadratus lumborum block in an adult patient undergoing inguinal hernia surgery: A prospective randomized controlled trial
Authors: Kumar Ajeet , Sinha Chandni , Singh Soumya , Kumar Amarjeet , Kumar Anil , Priya Diti 
Published: March 2024

Abstract

Background and Aims:
Inguinal hernia surgeries can pose significant postoperative pain, leading to chronic pain syndromes when not managed well.

Material and Methods:
Sixty American Society of Anesthesiologists (ASA) I/II adult patients scheduled to undergo unilateral inguinal hernia surgeries were enrolled in this trial. The patients were randomly allocated into three groups according to the various approaches of ultrasound-guided quadratus lumborum (QL) block: group transmuscular (TM): TM or anterior approach, group L: lateral approach, and group P: posterior approach. All the patients underwent surgery under subarachnoid blockade. A QL block was administered at the end of the surgery.

Results:
A total of 19 patients in each group were analyzed. Patients in the TM group had the least 24-hour requirement of fentanyl (P < 0.001), with better pain scores (P < 0.001) and prolonged duration of analgesia. No significant difference was found in the patient satisfaction scores (PSSs) in the three approaches. None of the patients reported any adverse effects related to the block.

Conclusion:
The TM approach of QL block is an effective analgesic strategy in patients undergoing unilateral hernia surgeries. It could form a part of the multimodal analgesic regimen for such patients.
Organizational Pathology and Crisis Management of Health and Treatment Experts: Effective Management Strategies in Dealing and Controlling the Epidemic of Coronavirus Disease 2019
Authors: Rouzbahani Rahim , Moghadam Afsaneh Zamani , Roodposhti Fereydoon Rahnamay 
Published: March 2024

Abstract

BACKGROUND:
Most studies on hospital crisis management demonstrated that the health-care systems are not sufficiently prepared to face a sudden pandemic. The purpose of this study is to evaluate the organizational pathology and crisis management of health and treatment experts during the pandemic, with an emphasis on coronavirus disease 2019 (COVID-19).

METHODS:
First, a systematic literature review to identify all relevant studies in accordance with hospital management and eligibility criteria was conducted. Thereafter, the structured method of developing consensus among panel members using Delphi method was designed. The expert panel consists of 10 specialized clinicians and four senior supervisors who were involved with hospital challenges during the COVID-19 pandemic. The samples were selected by snowball method since the researchers have difficulty finding participants for their studies.

RESULTS:
The final model presented includes six main dimensions, i.e., psychological, technology, screening and triage, management, economy, and human resources. Twenty components of model were self-assessment programs, management dashboard and classified information, management and monitoring, self-care training, triage training and human resources training, health waste management, essential training, emergency and flexible structures, organization of resources and facilities, efficiency of material resources and humanity and control of financial indicators, education and learning, professional development and empowerment.

CONCLUSION:
Strengthening the psychological infrastructure, technology, screening and triage, management, economy, and human resources in hospital management causes medical centers to have more organizational flexibility when crises occur and to experience new crisis management in the organization and before crises occur.
Prevalence of Anemia in Libyan Patients with Celiac Disease Before and After a Gluten-free Diet
Authors: Elbaruni Khaled Soliman , Abdulwahed Eman Ali , Alelwani Malak Ali , Abuhilika Thana Altaher , Atia Ahmed Elbadri 
Published: March 2024

Abstract

BACKGROUND:
This study aimed to estimate the incidence of anemia among celiac patients before and after their intake of a gluten-free diet (GFD).

METHODS:
A retrospective cross-sectional study was conducted in different departments of internal medicine, gastroenterology, and pediatrics at Tripoli University Hospital, Tripoli, Libya. The study data were retrospectively extracted from the clinical files of 100 patients who were diagnosed with celiac disease (CD). Hematological results of complete blood count for each patient before and after induction of GFD for 1 year were collected from the medical records. The data were analyzed using IBM SPSS version 26 software.

RESULTS:
Out of 100 CD patients, 53 patients were female and 47 patients were male. The analysis showed that the values of red blood cell, hemoglobin, hematocrit, mean cell hemoglobin (MCH), and MCH concentration were significantly higher after treatment compared to before one (P < 0.05). However, the independent t-test analysis did not show a significant difference in the mean values of white blood cell and red cell distribution width before and after treatment (P > 0.05). In addition, the mean value of platelets was lower after treatment with a P = 0.047.

CONCLUSION:
Anemia was a common finding in the studied cases. Although the GFD improved CD symptoms, anemia persisted in a number of CD patients, even after a year of GFD treatment.
Pre-Descemet’s endothelial keratoplasty with glued intraocular lens implantation with pinhole pupilloplasty in a case of ocular comorbidity in achromatopsia
Authors: Kumar Dhivya Ashok , Agarwal Amar , Ravichandran Swetha 
Published: March 2024

Abstract:
Ocular comorbidities can happen as congenital defective gene associations. We present a 37-year-old female patient who was mentally challenged and had coexisting achromatopsia gene abnormality on genetic analysis. She was operated in childhood for congenital cataract, and posterior chamber intraocular lens (IOL) was implanted at 10 years of age elsewhere. The patient presented 27 years later with luxated IOL with endothelial decompensation. There was a coexisting steep and thin cornea noted on corneal topography. She was managed with pre-Descemet’s endothelial keratoplasty with transpositioning of posterior chamber IOL to glued IOL with single-pass four-throw pupilloplasty. Postoperatively, the cornea was clear with centered glued IOL. The lesser postanesthetic challenges and faster rehabilitation are obtained in combination procedures with reduced complications in such rare scenarios.
Systemic treatment and surgical intervention in inflammatory Terrien disease
Authors: Arnalich-Montiel Francisco 
Published: March 2024

Abstract:
This case report presents a unique instance of a 55-year-old male patient exhibiting features of both Terrien marginal degeneration (TMD) and Fuchs’ superficial marginal keratitis. Characterized by peripheral corneal thinning vascularization, and a pseudopterygium, the patient experienced recurrent photophobia, redness, and tearing over 15 years. This case challenges the traditional distinction between TMD and Fuchs’ superficial marginal keratitis, suggesting a potential common underlying disorder. Mycophenolate mofetil provided a partial response, while pseudopterygium removal led to sustained remission, emphasizing its therapeutic significance. This case highlights the first documented use of mycophenolate in TMD and supports the notion of shared vasculitic origins between TMD and Fuchs’ keratitis, raising intriguing questions about targeted therapeutic interventions.
Analisis Pengaruh Ketimpangan Pembangunan Dan Pertumbuhan Ekonomi Terhadap Kemiskinan di Kabupaten Kepulauan Mentawai
Authors: Sani Jusman , Irsyad M , Kamarni Neng 
Published: March 2024

Penelitian ini bertujuan untuk menganalisis Pengaruh ketimpangan pembangunan dan pertumbuhan ekonomi terhadap kemiskinan di Kabupaten Kepulauan Mentawai. Pendekatan penelitian adalah kuantitatif dan metode yang digunakan dalam penelitian ini yaitu metode asosiatif. Data yang digunakan adalah data dari Badan Pusat Statistik yaitu data time series (kemiskinan, ketimpangan, PDRB tahun 2013 - 2022). Intrumen alat analisis menggunakan Regresi Linier berganda. Hasil penelitian menunjukkan bahwa secara parsial ketimpangan pembangunan tidak berpengaruh signifikan terhadap tingkat kemiskinan di Kabupaten Kepulauan Mentawai. Sementara itu pertumbuhan ekonomi berpengaruh secara signifikan terhadap tingkat kemiskinan di Kabupaten Kepulauan Mentawai.
Pengaruh Live Streaming, Advertising dan Affiliate Marketing Terhadap Minat Beli Di Shopee (Studi Kasus Pada Mahasiswa Fakultas Ekonomi dan Bisnis Universitas Dian Nuswantoro)
Authors: Siswanto Eliza Junita , Aryanto Vincent Didiek Wiet 
Published: March 2024

Setiap tahun terjadi kenaikan pengguna internet dan hal tersebut dapat dimanfaatkan sebagai peluang pengembangan bisnis bagi Shopee. Peluang tersebut ditunjukkan oleh jumlah pangsa pasar marketplace Shopee yang berada di urutan pertama mengalahkan kompetitornya. Penelitian ini dilakukan dengan tujuan untuk mengetahui beberapa faktor yang memberikan pengaruh kepada minat beli pengguna Shopee pada Fakultas Ekonomi dan Bisnis Dian Nuswantoro Semarang. Adapun faktor-faktor yang diteliti meliputi live streaming, advertising dan affiliate marketing. Populasi dalam penelitian ini meliputi para pengguna aplikasi Shopee dan merupakan mahasiswa Fakultas Ekonomi dan Bisnis Universitas Dian Nuswantoro Semarang. Pengambilan sampel pada penelitian ini menggunakan teknik purposive sampling kepada 105 responden yang diambil sebagai sampel pada penelitian ini. Pengumpulan data primer dilakukan dengan membagikan kuesioner melalui Google Form kepada para responden. Sedangkan untuk data sekunder berasal dari jurnal-jurnal dan literature dari penelitian terdahulu. Teknik analisis data yang digunakan ialah dengan menganalisis outer model yang mencakup uji validitas dan reliabilitas serta inner model yang mencakup uji multikolinearitas, uji Coefficient Determination, uji Effect Size, uji goodness of fit (GoF) dan uji hipotesis dengan menggunakan software pengolahan data SmartPLS-3. Dari penelitian ini, didapatkan hasil bahwa live streaming mempengaruhi minat beli secara signifikan, advertising mempengaruhi minat beli secara signifikan, sedangkan affiliate marketing tidak terlalu mempengaruhi minat beli.
Pengaruh Inovasi Produk, Physical Evidence, Experimental Marketing Dan Wom Communication Terhadap Minat Pembelian Ulang (Studi Kasus Pada Konsumen Kafe Bosque Coffee)
Authors: Efendi M. Youngky , Putri Intan Erlinia Eka Fatma , Taqwima Agni Pretty , Subroto Agus Andi , Mashudi Muhammad 
Published: March 2024

Pertumbuhan bisnis Kafe di Indonesia berkembang sangat pesat. Hal ini menjadikan penelitian dilakukan bertujuan untuk mengetahui Pengaruh Inovasi Produk, Physical Evidence, Experimental Marketing dan WOM Communication terhadap Pembelian ulang pada konsumen kafe Bosque Coffee. Penelitian ini merupakan jenis penelitian kuantitatif dengan teknik Purposive Sampling. Pengumpulan data menggunakan angket kuisioner G-form dengan kriterian minimal pembelian 2x di Kafe Bosque dengan jumlah 140 responden. Hasil penelitian ini menunjukkan bahwa Inovasi produk berpengaruh terhadap pembelian ulang karena konsumen menyukai produk yang sangat bervariatif. Physical Evidence berpengaruh terhadap pembelian ulang karena fasilitas dan rasa nyaman yang menarik minat konsumen. Experimental Marketing sangat berpengaruh terhadap pembelian ulang Karena jasa yang di berikan sangat baik. WOM Communication sangat berpengaruh terhadap pembelian ulang Karena informasi yang di berikan konsumen pada konsumen lain sangat mempengaruhi konsumen untuk datang
Analisis Perbandingan Kinerja Keuangan Bank Konvensional Dengan Bank Syariah
Authors: Anggraini Zareta Dianalisa , Ghafur Abd , Arifin Moh. Samsul 
Published: March 2024

Bank merupakan salah satu lembaga yang berperan sebagai perantara keuangan yang memiliki peran penting bagi perekonomian suatu negara. Diera globalisasi saat ini cukup banyak bank konvensional yang telah membuka atau mendirikan cabang yang bersifat syariah. Jenis data yang dalam pendekatan penelitian ini adalah data deskriptif komperatif melalui pendekatan kuantitatif. Sampel yang digunakan yaitu 3 bank konvensional yang terdiri dari bank BCA, bank BNI, dan bank BRI dan 3 bank syariah yang terdiri dari bank BSI, bank MEGA S, dan bank BTN S dengan periode tahun 2020-2022. Alat analisis yang digunakan dalam pengujian hipotesis pada penelitian ini ialah uji independen sampel t-test dan homogenitas sapiro wilk. Dengan pendekatan rasio Return On Asset (ROA), Return On Equity (ROE), Loan To Deposit Ration (LDR), Non Perfoming Loans (NPL), Capital Adequacy Ration (CAR), Biaya Operasional Pendapatan Operasional (BOPO). Hasil penelitian menunjukan nilai ROA tidak terdapat perbedaan yang signifikan, nilai ROE menunjukan ada perbedaan yang signifikan, nilai NPL tidak ada perbedaan yang signifikan, untuk nilai LDR ada perbedaan yang sifnifikan, nilai CAR juga memiliki perbedaan yang signifikan, dan untuk nilai BOPO memiliki perbedaan yang signifikan. Akan tetapi jika ditinjau dari aspek keseluruhan bank syariah belum mampu menunjukan kinerja keuangan lebih baik dibandingkan dengan kinerja keuangan bank konvensional.
ĐẶC ĐIỂM TỔN THƯƠNG ĐỘNG MẠCH VÀNH TRÊN CẮT LỚP VI TÍNH ĐA DÃY ĐẦU DÒ Ở BỆNH NHÂN ĐÁI THÁO ĐƯỜNG TÍP 2
Authors: Đỗ Võ Công Nguyên , Nghiêm Phương Thảo , Nguyễn Chí Thành , Trần Thanh Phong , Bùi Anh Thắng 
Published: March 2024

Mục tiêu: nghiên cứu nhằm đích mô tả đặc điểm hình ảnh và tỉ lệ tổn thương động mạch vành trên chụp cắt lớp vi tính đa dãy đầu dò ở bệnh nhân (BN) đái tháo đường (ĐTĐ) típ 2 và tìm hiểu mối liên quan giữa đặc điểm tổn thương động mạch vành (ĐMV) với một số đặc điểm bệnh nhân ĐTĐ típ 2. Phương pháp: Đây là nghiên cứu cắt ngang, hồi cứu. Tất cả các BN được chụp CLVT mạch vành ở bệnh viện Thống Nhất, Tp Hồ Chí Minh từ 9/2022 đến 9/2023. Kết quả: có 294 BN, trong đó có 147 BN nhóm ĐTĐ típ 2 (gồm 92 nam chiếm 62,6%, 55 nữ chiếm 37,4%) và 147 bệnh nhân không ĐTĐ (gồm 93 nam chiếm 63,3% và 54 nữ chiếm 36,7%). Tuổi trung bình (TB) của nhóm không ĐTĐ là 61,7 ±10,5, thấp hơn tuổi TB nhóm ĐTĐ là 68,4 ±8,9 (p<0,001). Nhóm không ĐTĐ ít bị tổn thương ĐMV hơn và số nhánh tổn thương cũng ít hơn so với nhóm ĐTĐ có ý nghĩa thống kê (p=0,002). Tỷ lệ hẹp các nhánh ĐMV : Động mạch (ĐM) liên thất trước (LAD), ĐM mũ (LCX), ĐMV phải (RCA) có ý nghĩa (hẹp ≥50%) ở nhóm không ĐTĐ thấp hơn nhóm ĐTĐ có ý nghĩa thống kê, ngoại trừ thân chung ĐMV trái (LM). Trong các nhánh mạch vành hẹp > 50% thì hẹp LAD chiếm tỉ lệ cao nhất, ở nhóm ĐTĐ (41,5%) và nhóm không ĐTĐ (27,2%). Điểm vôi hóa trung bình Agatston ở nhóm ĐTĐ là 234,9±395,8, cao hơn nhóm không ĐTĐ (106,7±334,2). Điểm vôi hoá ở các nhánh ĐMV ở nhóm ĐTĐ cao hơn nhóm không ĐTĐ có ý nghĩa thống kê với p<0,001. Diện tích dưới đường cong cho giá trị điểm vôi hoá trong tiên đoán hẹp ≥50% ĐMV là 0,839, với ngưỡng cut – off là 88 điểm, có độ nhạy và độ đặc hiệu cao nhất trong chẩn đoán lần lượt là 74,3% % và 79,5%. Chỉ có thời gian mắc ĐTĐ là có liên quan đến hẹp ĐMV (r=0,38). Kết luận: Cắt lớp vi tính đa dãy đầu dò đóng vai trò quan trọng trong phát hiện vôi hóa mạch vành, dự đoán mức độ hẹp mạch vành có ý nghĩa và chẩn đoán hẹp ĐMV, đặc biệt trên nhóm BN ĐTĐ.