bluuebunny/crossref_metadata_2025_split huggingface dataset:
From performance to horizon: managements’ horizon and firms’ investment efficiency
Authors: Tunyi Abongeh A. , Areneke Geofry , Hussain Tanveer , Agyemang Jacob 
Published: February 2024

Purpose
This study proposes a novel measure for management’s horizon (short-termism or myopia vs long-termism or hyperopia) derived from easily obtainable firm-level accounting and stock market performance data. The authors use the measure to explore the impact of managements’ horizon on firms’ investment efficiency.

Design/methodology/approach
The authors rely on two commonly used but uncorrelated measures of management performance: accounting performance (return on capital employed, ROCE) and stock market performance (average abnormal return, AAR). The authors combine these measures to develop a multidimensional framework for performance, which classifies firms into four groups: efficient (high accounting and high market performance), poor (low accounting and low market performance), myopic (high accounting and low market performance) and hyperopic (low accounting and high market performance). The authors validate this framework and deploy it to explore the relationship between horizon and firms’ investment efficiency.

Findings
In validation tests, the authors show that management myopia (hyperopia) explains firms’ decision to cut (grow) research and development investments. Further, as expected, myopic (hyperopic) firms are associated with significantly more (less) accrual and real earnings management. The empirical tests on the link between horizon and investment efficiency suggest that myopic managers cut new investments while their hyperopic counterparts grow the same. Ultimately, the authors find that myopia (hyperopia) exacerbates(mitigates) the over-investment of free cash flow problem.

Originality/value
The authors introduce a framework for assessing management’s horizon using easily obtainable measures of performance. The framework explains inconsistencies in prior empirical research using different measures of performance (accounting versus market). The authors demonstrate its utility by showing that the measure explains decisions around research and development investment, earnings management and firm investments.
Dietary habits in adult Japanese patients with vitiligo
Authors: Hamada Risa , Funasaka Yoko , Saeki Hidehisa , Serizawa Naotaka , Hagino Teppei , Yano Yumiko , Mitsui Hiroshi , Kanda Naoko 
Published: February 2024

AbstractVitiligo is an autoimmune skin disease with acquired depigmentation. Dietary habits may modulate the pathogenesis of vitiligo. We evaluated dietary habits in adult Japanese patients with nonsegmental vitiligo, and compared their results with those of age‐ and sex‐matched controls. We also examined the relationship between dietary habits and Vitiligo Area Scoring Index (VASI), or vitiligo on different anatomical sites. The intakes of energy, nutrients, and foods in the participants were analyzed using a brief‐type self‐administered diet history questionnaire. Patients with vitiligo showed higher body mass index (BMI) and lower intakes of manganese, vitamin D, pulses, and confection, compared with controls. Multivariate logistic regression analysis showed that vitiligo was associated with high BMI. VASI was higher in males than in females, and negatively correlated with age or intakes of potatoes and vegetables other than green/yellow vegetables. Linear multivariate regression analysis showed that high VASI was associated with younger age. Multivariate logistic regression analysis showed that moderate to severe vitiligo (VASI ≥ 4.25) was associated with male sex and longer disease duration. Multivariate logistic regression analyses showed the following association with vitiligo on respective anatomical sites: high intake of eggs and dairy products and high VASI on the head or neck, high intake of oils and fats and high VASI on the trunk, high intake of cereals and high VASI on the upper limbs, male sex and high VASI on the lower limbs, and high BMI and high VASI on the hands or feet. In conclusion, the control of obesity might have prophylactic or therapeutic effects on vitiligo.
Hematological parameters as diagnostic biomarkers for patients with rosacea
Authors: Liang Shuang , Fang Yan , Zhao Zhixiang , Wang Ben , Huang Yingxue , Xie Hongfu , Zhang Yiya , Li Ji 
Published: February 2024

AbstractRosacea is a chronic inflammatory skin disease. Systemic inflammation plays a vital role in the pathogenesis of rosacea. Many studies have reported hematological parameters as biomarkers for diseases with inflammatory processes. However, the diagnostic value of hematological parameters in rosacea remains a puzzle. This study involved 462 patients with rosacea, including erythematotelangiectatic rosacea (ETR, n = 179), papulopustular rosacea (PPR, n = 250), and phymatous rosacea (PhR, n = 33), and 924 healthy control subjects. Demographic, clinical, and laboratory information was collected and compared between rosacea subtypes. The hematological parameters of the patients and the healthy controls were compared retrospectively. The platelet volume (MPV) and platelet crit (PCT) were significantly upregulated, and the lower red cell distribution width (RDW) was significantly downregulated in rosacea compared to healthy controls, and they were identified as the diagnostic biomarkers for rosacea with area under the curve values of 0.828, 0.742, and 0.787, respectively. Comparing the hematological parameters among the three rosacea subtypes, we found that platelet‐to‐lymphocyte ratio and platelet‐to‐neutrophil ratio values in the ETR group were significantly higher than those in the PPR and PhR groups. The correlation between hematological parameters and clinical scores showed that RDW was negatively correlated with the Clinician Erythema Assessment score. However, there was no significant correlation between the Investigator Global Assessment score and hematological parameters. In conclusion, PCT, MPV, and RDW have diagnostic value for rosacea, and RDW is correlated with the severity of rosacea erythema, implying the potential applications of PCT, MPV, and RDW in the diagnosis and monitoring of rosacea.
Characterization and analysis of attenuation anisotropy in viscoelastic vertical transverse isotropic media
Authors: Xi Yijun , Yin Xingyao 
Published: February 2024

AbstractDue to the intrinsic attenuation of the earth, the study of wave propagation characteristics, considering seismic attenuation plays an important role in high‐precision reservoir prediction. Therefore, we investigate the propagation and reflection characteristics of seismic waves in viscoelastic vertical transverse isotropic media in the complex frequency domain. Specifically, we analyse the response characteristics of velocity, propagation vector and attenuation vector with respect to viscosity media with different attenuation intensities. Furthermore, based on the quasi‐Zoeppritz equation, the variation of reflection coefficient amplitude with offset at different attenuation angles and different attenuation intensities is studied. We also compare the trends in the amplitude variation of reflection coefficients with offset in elastic isotropic, elastic anisotropic and viscoelastic anisotropic media. Due to the complexity of the exact reflection coefficient expression, we first propose the approximate expression of the attenuation–anisotropy parameters and then derive the approximate expression of the reflection coefficient. The numerical simulation results show that the approximate expression of the reflection coefficient is still accurate, even in media with strong anisotropy. Finally, the accuracy evaluations of the reflection coefficient formulas using four typical theory models demonstrate that the approximate reflection coefficient formulas are highly accurate in both weak and strong anisotropic media.
Fish microbiota repel ovipositing mosquitoes
Authors: Shteindel Nimrod , Gerchman Yoram , Silberbush Alon 
Published: February 2024

Abstract

The mere presence of predators causes prey organisms to display predation‐avoidance strategies. Predator presence is often communicated through predator‐released chemical signals. Ovipositing female mosquitoes of several species are repelled by unknown signals released from larvivorous fish.

It was previously suggested that in many cases, a predator's microbiota plays an important role in the release of these signals; however, this mechanism is still poorly understood.

In this study, we looked into the effects of the microbiota originating from the larvivorous Gambusia affinis (Baird and Girard) on the oviposition behaviour of gravid female mosquitoes. We used fish with altered microbiota and bacterial isolates in a set of outdoor mesocosm experiments to address this aim.

We show that interference with the fish microbiota significantly reduces fish's repellent effect. We further show that the bacterium Pantoea pleuroti, isolated from the skin of the fish, repels oviposition of Culex laticinctus Edwards and Culiseta longiareolata Macquart mosquitoes similarly to the way in which live fish repel them.

Our results highlight the importance of bacteria in the interspecies interactions of their hosts. Furthermore, this finding may lead to the development of an ecologically friendly mosquito repellent, that may reduce the use of larvivorous fish for mosquito control.
Minimum labelling requirements for dermatology artificial intelligence‐based Software as Medical Device (SaMD): A consensus statement
Authors: Ingvar Åsa , Oloruntoba Ayooluwatomiwa , Sashindranath Maithili , Miller Robert , Soyer H. Peter , Guitera Pascale , Caccetta Tony , Shumack Stephen , Abbott Lisa , Arnold Chris , Lawn Craig , Button‐Sloan Alison , Janda Monika , Mar Victoria 
Published: February 2024

AbstractBackground/ObjectivesArtificial intelligence (AI) holds remarkable potential to improve care delivery in dermatology. End users (health professionals and general public) of AI‐based Software as Medical Devices (SaMD) require relevant labelling information to ensure that these devices can be used appropriately. Currently, there are no clear minimum labelling requirements for dermatology AI‐based SaMDs.MethodsCommon labelling recommendations for AI‐based SaMD identified in a recent literature review were evaluated by an Australian expert panel in digital health and dermatology via a modified Delphi consensus process. A nine‐point Likert scale was used to indicate importance of 10 items, and voting was conducted to determine the specific characteristics to include for some items. Consensus was achieved when more than 75% of the experts agreed that inclusion of information was necessary.ResultsThere was robust consensus supporting inclusion of all proposed items as minimum labelling requirements; indication for use, intended user, training and test data sets, algorithm design, image processing techniques, clinical validation, performance metrics, limitations, updates and adverse events. Nearly all suggested characteristics of the labelling items received endorsement, except for some characteristics related to performance metrics. Moreover, there was consensus that uniform labelling criteria should apply across all AI categories and risk classes set out by the Therapeutic Goods Administration.ConclusionsThis study provides critical evidence for setting labelling standards by the Therapeutic Goods Administration to safeguard patients, health professionals, consumers, industry, and regulatory bodies from AI‐based dermatology SaMDs that do not currently provide adequate information about how they were developed and tested.
Investigating causal relationships between the gut microbiota and inflammatory skin diseases: A Mendelian randomization study
Authors: Gu Yunfan , Zhang Weiming , Zhao Wenting , Zeng Xianyu 
Published: February 2024

AbstractBackgroundNumerous inflammatory skin diseases are associated with the gut microbiota. Studies of the association between gut microbiota and inflammatory skin diseases have yielded conflicting results owing to confounding factors, and the causal relationship between them remains undetermined.MethodsTwo‐sample Mendelian randomization (MR) was used to examine the association between gut microbiota and four common inflammatory skin diseases: acne, psoriasis, urticaria and atopic dermatitis. The summary statistics of the gut microbiota from the largest available genome‐wide association study meta‐analysis (n = 13,266) conducted by the MiBioGen consortium along with the summary statistics of the four diseases were obtained from the FinnGen consortium. Causal relationships were assessed using the inverse variance weighted (IVW), weighted median, MR‐Egger and maximum likelihood methods, and several sensitivity analyses were performed to ensure the accuracy of the results. Finally, reverse and multivariable MR analyses were performed to verify the robustness of the results.ResultsWe found causal associations of Bacteroidaceae [odds ratio (OR), 2.25; 95% confidence interval (CI), 1.48–3.42; pivw = 0.0001], Allisonella (OR, 1.42; 95% CI, 1.18–1.70; pivw = 0.0002) and Bacteroides (OR, 2.25; 95% CI, 1.48–3.42; pivw = 0.0001) with acne, the Eubacterium fissicatena group with psoriasis (OR, 1.22; 95% CI, 1.10–1.35; pivw = 0.0002) and Intestinibacter with urticaria (OR, 1.28; 95% CI, 1.13–1.45; pivw = 0.0001). These results were corrected for a false discovery rate. Sensitivity analyses were performed to validate the robustness of the associations and reverse MR confirmed that the results were not influenced by the reverse effect.ConclusionOur study revealed that some gut microbiota are risk factors for inflammatory skin diseases, providing new information on potential therapeutic targets. Additionally, a possible association with the gut–skin axis was confirmed. Further research is required to elucidate the mechanisms underlying these relationships.
Is authority fungible? Legitimacy, domain congruence, and the limits of power in Africa
Authors: Baldwin Kate , Kao Kristen , Lust Ellen 
Published: February 2024

AbstractScholars increasingly recognize the plurality of leaders who exercise de facto authority in governing communities. But what limits different leaders’ power to organize distinct types of collective action beyond the law? We contend that leaders’ influence varies by activity, depending on the degree to which the activity matches the leaders’ geographic scope and field of expertise (“domain congruence”). Employing conjoint endorsement experiments in Kenya, Malawi, and Zambia, we test whether domain congruence predicts citizens’ willingness to comply with leader requests across different activities and examine the mechanisms that explain its importance. We find limits on leaders’ authority, that the concept of domain congruence helps predict the activities over which leaders have the greatest influence, and that leaders’ domain legitimacy may underpin the relationship between domain congruence and authority.
The impact of extreme heat on older regional and rural Australians: A systematic review
Authors: Harvey Grace , Bain‐Donohue Suzanne , Dewi Sari Puspa 
Published: February 2024

AbstractIntroductionExtreme heat causes a major health burden, especially for older Australians.ObjectiveTo assess the impact of extreme heat on older regional and rural Australians, including clinical presentations, social implications, and health‐seeking behaviours and adaptations.DesignA systematic review and narrative synthesis.FindingsTen articles were included in the review with research on this topic limited. Extreme heat causes an increase in mortality and ambulance dispatches for older rural Australians. Social connectedness is negatively affected by extreme heat due to cancellation of events and individuals becoming housebound. Air conditioning is the main cooling mechanism used, although cost is a major concern. Despite this, older rural populations display a depth of knowledge regarding practical behavioural responses to adapt to extreme heat. Studies show older rural Australians do not consider extreme heat to be a threat to health.DiscussionFurther research needs to examine the role extreme heat may play in contributing to experiences of loneliness. Air conditioning cannot be the ultimate solution in responding to extreme heat due to cost and increased carbon emissions. The low‐risk perception of extreme heat for older rural people may inform effective heat health warnings and effective use of primary health care in heat‐health education. Listening to First Nations knowledge in dealing with heat may provide a powerful mechanism in which to protect health.ConclusionThe extensive health effects of extreme heat highlights the necessity of further research and strengthening of services in preparation for an ageing rural population enduring climate change.
Association between gut microbiota development and allergy in infants born during pandemic‐related social distancing restrictions
Authors: Korpela Katri , Hurley Sadhbh , Ford Sinead Ahearn , Franklin Ruth , Byrne Susan , Lunjani Nonhlanhla , Forde Brian , Neogi Ujjwal , Venter Carina , Walter Jens , Hourihane Jonathan , O'Mahony Liam ,   CORAL Study Group
Published: February 2024

AbstractBackgroundSeveral hypotheses link reduced microbial exposure to increased prevalence of allergies. Here we capitalize on the opportunity to study a cohort of infants (CORAL), raised during COVID‐19 associated social distancing measures, to identify the environmental exposures and dietary factors that contribute to early life microbiota development and to examine their associations with allergic outcomes.MethodsFecal samples were sequenced from infants at 6 (n = 351) and repeated at 12 (n = 343) months, using 16S sequencing. Published 16S data from pre‐pandemic cohorts were included for microbiota comparisons. Online questionnaires collected epidemiological information on home environment, healthcare utilization, infant health, allergic diseases, and diet. Skin prick testing (SPT) was performed at 12 (n = 343) and 24 (n = 320) months of age, accompanied by atopic dermatitis and food allergy assessments.ResultsThe relative abundance of bifidobacteria was higher, while environmentally transmitted bacteria such as Clostridia was lower in CORAL infants compared to previous cohorts. The abundance of multiple Clostridia taxa correlated with a microbial exposure index. Plant based foods during weaning positively impacted microbiota development. Bifidobacteria levels at 6 months of age, and relative abundance of butyrate producers at 12 months of age, were negatively associated with AD and SPT positivity. The prevalence of allergen sensitization, food allergy, and AD did not increase over pre‐pandemic levels.ConclusionsEnvironmental exposures and dietary components significantly impact microbiota community assembly. Our results also suggest that vertically transmitted bacteria and appropriate dietary supports may be more important than exposure to environmental microbes alone for protection against allergic diseases in infancy.
Evaluating the impact of pre‐diagnostic use of statins and testosterone replacement therapy on mortality outcomes in older men with hormone‐related cancers: Surveillance, Epidemiology, and End Results‐Medicare 2007–2015
Authors: Hussain Maryam R. , Abdelgadir Omer , Polychronopoulou Efstathia , Tsilidis Konstantinos K. , Alzweri Laith , Villasante‐Tezanos Alejandro , Baillargeon Jacques , Canfield Steven , Kuo Yong‐Fang , Lopez David S. 
Published: February 2024

AbstractBackgroundThe link between the pre‐diagnostic use of statins and testosterone replacement therapy and their impact on hormone‐related cancers, prostate cancer, colorectal cancer, and male breast cancer survival remains a topic of controversy. Further, there is a knowledge gap concerning the joint effects of statins and testosterone replacement therapy on hormone‐related cancer survival outcomes.ObjectiveTo examine the independent and joint effects of pre‐diagnostic use of statins and testosterone replacement therapy on the risk of all‐cause and cause‐specific mortality among older men diagnosed with hormone‐related cancers, including prostate cancer, colorectal cancer, and male breast cancer.MethodsIn 41,707 men (≥65 years) of Surveillance, Epidemiology, and End Results‐Medicare 2007–2015, we identified 31,097 prostate cancer, 10,315 colorectal cancer, and 295 male breast cancer cases. Pre‐diagnostic prescription of statins and testosterone replacement therapy was ascertained and categorized into four groups (Neither users, statins alone, testosterone replacement therapy alone, and Dual users). Multivariable‐adjusted Cox proportional hazards and competing‐risks (Fine‐Gray subdistribution hazard) models were conducted.ResultsNo significant associations were found in Cox‐proportional hazard models for hormone‐related cancers. However, in the Fine‐Gray competing risk models among high‐grade hormone‐related cancers, statins alone had an 11% reduced risk of hormone‐related cancer‐specific death (hazard ratio: 0.89; 95% confidence interval: 0.81–0.99; p 0.0451). In the prostate cancer cohort with both statistical models, the use of testosterone replacement therapy alone had a 24% lower risk of all‐cause death (hazard ratio: 0.76; 95% confidence interval: 0.59–0.97; p 0.0325) and a 57% lower risk of prostate cancer‐specific death (hazard ratio: 0.43; 95% confidence interval: 0.24–0.75; p 0.0029). Similar inverse associations were found among aggressive prostate cancer cases with testosterone replacement therapy alone and statins alone. No significant associations were found in the colorectal cancer and male breast cancer sub‐groups.ConclusionPre‐diagnostic use of statins and testosterone replacement therapy showed a survival benefit with reduced mortality in high‐grade hormone‐related cancer patients (only statins) and aggressive prostate cancer patients in both statistical models. Findings of testosterone replacement therapy use in aggressive prostate cancer settings could facilitate clinical trials. Further studies with extended follow‐up periods are needed to substantiate these findings.
Work Overload, Work–Life Balance and Auditors' Turnover Intention: The Moderating Role of Motivation
Authors: Alves Iryna , Limão Miguel , Lourenço Sofia M. 
Published: February 2024

AbstractAuditor turnover remains a persistent concern for regulatory bodies and auditing firms. Past research on auditors’ turnover intention has explored various factors influencing auditors’ turnover intention, including job satisfaction, organisational commitment, work overload and work–life balance. However, the potential role of motivation in mitigating the adverse effects of work overload and work–life imbalance has been overlooked. Our study addresses this gap in the existing literature by revealing the crucial role of motivation and identifying differences between Big4 and Non‐Big4 firms. Using questionnaire data from 301 auditors, analysed using structural equation modelling, we find that work overload is positively but indirectly related to turnover intention via work–life balance. Additionally, organisational commitment (job satisfaction) is directly (indirectly) and negatively related to turnover intention. Moreover, and considering that, due to work overload, a lack of work–life balance can be responsible for increasing auditors’ turnover intention, our study suggests that motivation can mitigate this effect. Finally, our study suggests that work–life balance can directly reduce turnover intention for Big4 firms, while for Non‐Big4 firms this reduction can only occur via organisational commitment (a channel that is weaker for Big4 firms).