bluuebunny/crossref_metadata_2025_split huggingface dataset:
Severe kidney dysfunction after assisted reproductive technology: a case series suggesting the need for higher awareness of risks
Authors: Nagy Eman , Shemies Rasha , Taman Mohamed , Sayed-Ahmed Nagy , Piccoli Giorgina Barbara 
Published: February 2025

Abstract

Background
Assisted reproductive technology (ART) has significantly increased the rate of conception and live births in women with fertility problems. Having a kidney disease negatively affects a woman’s reproductive health, making infertility a significant concern, and women with chronic kidney disease (CKD) are increasingly seeking treatment with assisted reproductive technology. The side effects of assisted reproductive technology are not fully known and its impact on kidney function, especially if a woman has undergone repeated treatments, is likewise not known.

Methods
This case series gathers all consecutive patients who were followed by the Mansoura University Hospital’s Obstetric Nephrology Service or were admitted to its Nephrology and Gynecology Department during pregnancy with a diagnosis of acute or chronic kidney function impairment after conceiving with an assisted reproductive technology method, in the period from 2021 to 2024.

Results
Of the approximately 150 pregnancies referred to the Obstetric Nephrology Clinic, 6 were referred for acute or acute-on-chronic kidney function impairment, or nephrotic syndrome after conceiving via assisted reproductive technology. In one patient, CKD was overlooked and later progressed to kidney failure; one had probable CKD, but discontinued follow-up before confirmation; and one had a kidney malformation, diagnosed during pregnancy. All presented with early or very early severe hypertension and proteinuria, before 20 weeks, while preeclampsia and the hypertensive disorders of pregnancy are conventionally defined as developing after 20 weeks of gestation. Three had complete recovery postpartum, one progressed to kidney failure, while two were lost to follow-up.

Conclusion
Severe early-pregnancy kidney impairment after assisted reproductive technology is probably more frequent than previously reported. Assessment of kidney function after assisted reproductive technology should be mandatory, to make it possible for timely specialized kidney care to be given.

Graphical abstract
Capitalizing on a crisis: a computational analysis of all five million British firms during the Covid-19 pandemic
Authors: Muggleton Naomi , Rahal Charles , Reeves Aaron 
Published: February 2025

Abstract
The Covid-19 pandemic brought unprecedented changes to business ownership in the UK which affects a generation of entrepreneurs and their employees. Nonetheless, the impact remains poorly understood. This is because research on capital accumulation has typically lacked high-quality, individualized, population-level data. We overcome these barriers to examine who benefits from economic crises through a computationally orientated lens of firm creation. Leveraging a comprehensive cache of administrative data on every UK firm and all nine million people running them, combined with probabilistic algorithms, we conduct individual-level analyzis to understand who became Covid entrepreneurs. Using these techniques, we explore characteristics of entrepreneurs—such as age, gender, region, business experience, and industry—which potentially predict Covid entrepreneurship. By employing an automated time series model selection procedure to generate counterfactuals, we show that Covid entrepreneurs were typically aged 35–49 (40.4%), men (73.1%), and had previously held roles in existing firms (59.4%). For most industries, growth was disproportionately concentrated around London. It was therefore existing corporate elites who were most able to capitalize on the Covid crisis and not, as some hypothesized, young entrepreneurs who were setting up their first businesses. In this respect, the pandemic will likely impact future wealth inequalities. Our work offers methodological guidance for future policymakers during economic crises and highlights the long-term consequences for capital and wealth inequality.
Warum unterstützt die Bevölkerung ein autoritäres Regime? Neuere politikwissenschaftliche Forschungen über die Popularität Wladimir Putins
Authors: Stykow Petra 
Published: February 2025

Zusammenfassung
Viele autoritäre Regime der Gegenwart sichern ihre Macht nicht mit Gewalt, sondern erfreuen sich bei der Mehrheit der Bevölkerung nachweislich hoher Popularität. Dieses Phänomen, dem in der Vergleichenden Autoritarismusforschung erst seit wenigen Jahren größere Aufmerksamkeit geschenkt wird, ist am besten für Russland erforscht. Der Beitrag diskutiert neoinstitutionalistisch, legitimationstheoretisch, sozialpsychologisch und sozialstrukturell argumentierende Antworten auf die Frage nach der Beliebtheit Wladimir Putins und der Regime-Unterstützung durch die Bevölkerung. Abschließend werden einige Herausforderungen skizziert, der sich die einschlägige Forschung seit dem Beginn des vollumfänglichen Krieges gegen die Ukraine ausgesetzt sieht.
Mapping the exposome of mental health: exposome-wide association study of mental health outcomes among UK Biobank participants
Authors: Arias-Magnasco Angelo , Lin Bochao Danae , Pries Lotta-Katrin , Guloksuz Sinan 
Published: February 2025

Abstract

Background
Dissecting the exposome linked to mental health outcomes can help identify potentially modifiable targets to improve mental well-being. However, the multiplicity of exposures and the complexity of mental health phenotypes pose a challenge that requires data-driven approaches.

Methods
Guided by our previous systematic approach, we conducted hypothesis-free exposome-wide analyses to identify factors associated with 7 psychiatric diagnostic domains and 19 symptom dimensions in 157,298 participants from the UK Biobank Mental Health Survey. After quality control, 294 environmental, lifestyle, behavioral, and economic variables were included. An Exposome-Wide Association Study was conducted per outcome in two equally split datasets. Variables associated with each outcome were then tested in a multivariable model.

Results
Across all diagnostic domains and symptom dimensions, the top three exposures were childhood adversities and traumatic events. Cannabis use was associated with common psychiatric disorders (depressive, anxiety, psychotic, and bipolar manic disorders), with ORs ranging from 1.10 to 1.79 in the multivariable models. Additionally, differential associations were identified between specific outcomes—such as neurodevelopmental disorders, eating disorders, and self-harm behaviors—and exposures, including early life experiences (being adopted), lifestyle (time spent using computers), and dietary habits (vegetarian diet).

Conclusions
This comprehensive mapping of the exposome revealed that several factors, particularly in the domains of those previously well-studied were shared across mental health phenotypes, providing further support for transdiagnostic pathoetiology. Our findings also showed that distinct relations might exist. Continued exposome research through multimodal mechanistic studies guided by the transdiagnostic mental health framework is required to better inform public health policies.
Using SARS-CoV-2 nucleoprotein antibodies to detect (re)infection
Authors: Hoeve Christel E. , Neppelenbroek Nienke , Vos Eric R.A. , Huiberts Anne J. , Andeweg Stijn P. , den Hartog Gerco , van Binnendijk Robert , de Melker Hester , van den Hof Susan , Knol Mirjam 
Published: February 2025

Abstract
We assessed the validity of serum total anti-nucleoprotein Immunoglobulin (N-antibodies) to identify SARS-CoV-2 (re)infections by estimating the persistence of N-antibody seropositivity and boosting following infection. From a prospective Dutch cohort study (VASCO), we included adult participants with ≥2 consecutive self-collected serum samples, 4–8 months apart, between May 2021–May 2023. Sample pairs were stratified by N-seropositivity of the first sample and by self-reported infection within the sampling interval. We calculated the proportions of participants with N-seroconversion and fold-increase (1.5, 2, 3, 4) of N-antibody concentration over time since infection and explored determinants. We included 67,632 sample pairs. Pairs with a seronegative first sample (70%) showed 89% N-seroconversion after reported infection and 11% when no infection was reported. In pairs with a seropositive first sample (30%), 82%–65% showed a 1.5- to 4-fold increase with a reported reinfection, and 19%–10% without a reported reinfection, respectively. After one year, 83% remained N-seropositive post-first infection and 93%–61% showed a 1.5-fold to 4-fold increase post-reinfection. Odds for seroconversion/fold increase were higher for symptomatic infections and Omicron infections. In the current era with limited antigen or PCR testing, N-serology can be validly used to detect SARS-CoV-2 (re)infections at least up to a year after infection, supporting the monitoring of COVID-19 burden and vaccine effectiveness.
Characteristics and risk factors associated with COVID-19 reinfection in Hong Kong: a retrospective cohort study
Authors: Lin Wenhua , Kung Kin Hang , Chan Chung Lam , Chuang Shuk Kwan , Au Ka Wing 
Published: February 2025

Abstract
We aimed to identify risk factors related to COVID-19 reinfection in Hong Kong. We performed a population-based retrospective cohort study and reviewed case-based data on COVID-19 infections reported to the Centre for Health Protection from 8 January 2020 to 29 January 2023. We analyzed the epidemiology of COVID-19 infections and performed a Cox regression analysis. In this period, 3.32% (103,065/3,106,579) of COVID-19 infections recorded were classified as reinfection. Compared with primarily infected cases, a higher proportion of re-infected cases had chronic diseases (33.54% vs. 27.27%) and were residents of residential care homes (RCH) (10.99% vs. 1.41%). The time interval between the two episodes ranged from 31 to 1,050 days (median 282 days). Cox regression analysis of Omicron cases with the adjustment of covariates showed that being female (Hazard Ratio [HR] 1.12, 95% CI 1.11–1.13), chronic diseases (HR 1.18, 95% CI 1.16–1.20) and RCH residents (HR 6.78, 95% CI 6.61–6.95) were associated with reinfection, while additional vaccination after primary infection was protective (HR 0.80, 95% CI 0.79–0.81). Further analytical studies on the risk factors and protectors of COVID-19 reinfection are needed to guide targeted interventions.
An intervention in the paediatric cardiac ICU to standardise pre-family meeting huddles is feasible, acceptable, and improves clinician teamwork
Authors: Walter Jennifer K. , Cetin Arzu , Gramszlo Colette , DeWitt Aaron G. , Quarshie William , Griffis Heather , Johnson Victoria , Nelson Selena , Shults Justine , Arnold Robert M. , Trowbridge Amy , Hurd Caroline , Curley Martha A.Q. , Feudtner Chris 
Published: February 2025

Abstract

Introduction:
Interprofessional teams in the pediatric cardiac ICU consolidate their management plans in pre-family meeting huddles, a process that affects the course of family meetings but often lacks optimal communication and teamwork.

Methods:
Cardiac ICU clinicians participated in an interprofessional intervention to improve how they prepared for and conducted family meetings. We conducted a pretest–posttest study with clinicians participating in huddles before family meetings. We assessed feasibility of clinician enrollment, assessed clinician perception of acceptability of the intervention via questionnaire and semi-structured interviews, and impact on team performance using a validated tool. Wilcoxon rank sum test assessed intervention impact on team performance at meeting level comparing pre- and post-intervention data.

Results:
Totally, 24 clinicians enrolled in the intervention (92% retention) with 100% completion of training. All participants recommend cardiac ICU Teams and Loved ones Communicating to others and 96% believe it improved their participation in family meetings. We exceeded an acceptable level of protocol fidelity (>75%). Team performance was significantly (p < 0.001) higher in post-intervention huddles (n = 30) than in pre-intervention (n = 28) in all domains. Median comparisons: Team structure [2 vs. 5], Leadership [3 vs. 5], Situation Monitoring [3 vs. 5], Mutual Support [ 3 vs. 5], and Communication [3 vs. 5].

Conclusion:
Implementing an interprofessional team intervention to improve team performance in pre-family meeting huddles is feasible, acceptable, and improves team function. Future research should further assess impact on clinicians, patients, and families.
Einfühlsam Gespräche führen
Authors: Schirmer Uwe Bernd 
Published: February 2025

Erfolgreiches Praxishandbuch zur wertschätzenden und empathischen Gesprächsführung für Gesundheits-, Erziehungs-, Pflege- und Sozialberufe, das die Themen Empathie und Beziehung in den Mittelpunkt stellt. Der erfahrene Autor führt in die Grundlagen wertschätzend und einfühlsam geführter Gespräche ein und stellt den empathischen Prozess mit seinen Elementen Beobachtung, Gefühle und Bedürfnisse vor. Praxisnah beschreibt er Anwendungsbeispiele, Grenzen, Risiken und Strategien der empathischen Kommunikation für alle Fachberufe in der Medizin, Pflege, Psychologie, Sozialen Arbeit und Pädagogik, die professionell Entwicklungs- und Fürsorgearbeit leisten.Die 2. Auflage wurde inhaltlich vollständig überarbeitet und erweitert, die Grafiken wurden angepasst und erneuert. Die Literatur und Links wurden aktualisiert. Zentrale Konzepte und Interventionen, wie Gefühle, Bedürfnisse, Beziehung, Empathie, sowie Macht und Machtmissbrauch wurden aktualisiert und bearbeitet. Die Themen Vertrauen in Beziehungen, sowie professionelle Nähe und professionelle Distanz wurde aufgenommen und Perspektiven der Bewältigung aufgezeigt.Aus dem Inhalt	Zur Handhabung dieses Buches	Die Bedeutung von Beziehungen	Empathie	Wertschätzende und empathische Gesprächsführung	Anwendung der wertschätzenden und einfühlsamen Gesprächsführung	Die Perspektive der Bewältigung	Fazit und Ausblick	Anhang
Multi‐Event Analysis of STEVE, SAR Arc, and Red/Green Arc at Subauroral Latitudes Using Data From Ground Optical and Radio Instruments and the Arase and Van Allen Probes Satellites
Authors: Sugimura Rei , Shiokawa Kazuo , Otsuka Yuichi , Oyama Shin‐ichiro , Oksanen Arto , Connors Martin , Kadokura Akira , Poddelsky Igor , Nishitani Nozomu , Shepherd Simon G. , Ruohoniemi J. Michael , Smith Charles , Spence Harlan , Reeves Geoff , Funsten Herbert O. , Miyoshi Yoshizumi , Shinohara Iku , Kasahara Yoshiya , Tsuchiya Fuminori , Kumamoto Atsushi , Shinbori Atsuki , Asamura Kazushi , Yokota Shoichiro , Kazama Yoichi , Jun C.‐W. , Wang Shiang‐Yu , Tam Sunny W. Y. , Chang Tzu‐Fang , Wang Bo‐Jhou , Kasahara Satoshi , Keika Kunihiro , Hori Tomoaki , Matsuoka Ayako 
Published: February 2025

AbstractStrong Thermal Emission Velocity Enhancement (STEVE) is a latitudinally narrow, purple‐band emission observed at subauroral latitudes. Stable Auroral Red (SAR) arcs characterized by major red emission, and red/green arcs with both red and green emissions also occur at subauroral latitudes. Characteristics of magnetospheric source plasma and electromagnetic fields of these three types of arcs have not been fully understood because of the limited conjugate observations between magnetosphere and the ground. In this study, we report 11 conjugate observations (2 STEVEs, 7 SAR arcs, and 2 red/green arcs), using all‐sky images obtained at seven ground stations over more than four years from January 2017 to April 2021 and magnetospheric satellites (Arase and Van Allen Probes). We found that, in the inner magnetosphere, the source region of STEVEs and red/green arcs were located outside the plasmasphere, and that of the SAR arc was in the region of spatial overlap between the plasmasphere and ring current region. Electromagnetic waves at frequencies below 1 Hz were observed for STEVEs and red/green arcs. SuperDARN radar data showed a strong westward plasma flow in the ionosphere, especially during STEVE events, whereas the plasma flows associated with SAR arcs and red/green arcs were generally weaker and variable. The STEVE and SAR arc can appear simultaneously at slightly different latitudes and STEVEs and red/green arcs can transform into SAR arcs. These first comprehensive ground‐satellite measurements of three types of subauroral‐latitude auroras increase our understanding on similarlity, differences, and coupling of these auroras in the ionosphere and the magnetosphere.
Electron Dynamics Within Dispersive Scale Alfvénic Field‐Line Resonances Embedded Within Substorm Auroral Beads
Authors: Damiano P. A. , Kim E.‐H. , Johnson J. R. , Hull A. J. , Wing S. , Chaston C. C. , Delamere P. A. 
Published: February 2025

AbstractRecent Cluster satellite observations have illustrated that substorm auroral bead formation and currents are associated with the presence of dispersive scale standing Alfvén waves, which are also known as kinetic scale field line resonances (KFLRs) or kinetic Alfvén eigenmodes. In this work, the properties of these waves are further examined using simulations of a gyrofluid‐kinetic electron model in conjunction with the Cluster observations at mid‐latitudes and Defense Meteorological Satellite Program satellite observations at high‐latitudes. These simulations incorporate, for the first time, the effects of both hot magnetospheric and cold ionospheric electron populations within the multi‐period evolution of KFLRs. The simulation results demonstrate consistent characteristics with the observed energized electron distributions both at mid‐ and high‐latitudes. Tracing of the energized particle evolution shows that electrons can effectively interact with the wave all along the field line. Quantified energy conversion rates (as determined from ) show that significant wave energy dissipation occurs at all latitudes with a maximum occurring in the vicinity of the peak in the profile of the magnetic field to density ratio . Additionally, even though dispersive effects lead to the propagation of wave energy across field lines, the particle energization leads to rapid damping of the resonant system in only a few Alfvén periods.
Ensemble‐Based Spatially Distributed CLM5 Hydrological Parameter Estimation for the Continental United States
Authors: Yan Hongxiang , Sun Ning , Eldardiry Hisham , Thurber Travis , Reed Patrick , Kennedy Daniel , Swenson Sean , Rice Jennie 
Published: February 2025

AbstractOne of the major challenges in large‐domain hydrological modeling efforts lies in the estimation of spatially distributed hydrological parameters while simultaneously accounting for their associated uncertainties. Addressing this challenge is particularly difficult in ungauged locations. With growing societal demands for large‐scale streamflow projections to inform water resource management and long‐term planning, evaluating and constraining hydrological parameter uncertainty is increasingly vital. This study introduces a hybrid regionalization approach to enhance hydrological predictions of the Community Land Model version 5 (CLM5) across the Continental United States (CONUS), with a total of 50,629 1/8° grid cells. This hybrid method combines the strengths of two existing techniques: parameter regionalization and streamflow signature regionalization. It identifies ensemble behavioral parameters for each 1/8° grid cell across the CONUS domain, tailored to three distinct streamflow signatures focused on low flows, high flows, and annual water balance. Evaluating this hybrid method for 464 CAMELS (Catchment Attributes and Meteorology for Large‐sample Studies) basins demonstrates a significant improvement in CLM5 hydrological predictions, even in challenging arid regions. In CONUS applications, the derived spatially distributed parameter sets capture both spatial continuity and variation of parameters, highlighting their heterogeneous nature within specific regions. Overall, this hybrid regionalization approach offers a promising solution to the complex task of improving hydrological modeling over large domains for important hydrological applications.
Critical band-to-band-tunnelling based optoelectronic memory
Authors: Xu Hangyu , Xie Runzhang , Miao Jinshui , Zhang Zhenhan , Ge Haonan , Shi Xuming , Luo Min , Wang Jinjin , Li Tangxin , Fu Xiao , Ho Johnny C. , Zhou Peng , Wang Fang , Hu Weida 
Published: February 2025

Abstract
Neuromorphic vision hardware, embedded with multiple functions, has recently emerged as a potent platform for machine vision. To realize memory in sensor functions, reconfigurable and non-volatile manipulation of photocarriers is highly desirable. However, previous technologies bear mechanism challenges, such as the ambiguous optoelectronic memory mechanism and high potential barrier, resulting in a limited response speed and a high operating voltage. Here, for the first time, we propose a critical band-to-band tunnelling (BTBT) based device that combines sensing, integration and memory functions. The nearly infinitesimal barrier facilitates the tunnelling process, resulting in a broadband application range (940 nm). Furthermore, the observation of dual negative differential resistance (NDR) points confirms that the critical BTBT of photocarriers contributes to the sub-microsecond photomemory speed. Since the photomemory speed, with no motion blur, is important for motion detection, the critical BTBT memory is expected to enable moving target tracking and recognition, underscoring its superiority in intelligent perception.
An ingestible bioimpedance sensing device for wireless monitoring of epithelial barriers
Authors: Holt Brian M. , Stine Justin M. , Beardslee Luke A. , Ayansola Hammed , Jin Younggeon , Pasricha Pankaj J. , Ghodssi Reza 
Published: February 2025

Abstract
Existing gastrointestinal (GI) diagnostic tools are unable to non-invasively monitor mucosal tight junction integrity in vivo beyond the esophagus. In the GI tract, local inflammatory processes induce alterations in tight junction proteins, enhancing paracellular ion permeability. Although transepithelial electrical resistance (TEER) may be used in the laboratory to assess mucosal barrier integrity, there are no existing methodologies for characterizing tight junction dilation in vivo. Addressing this technology gap, intraluminal bioimpedance sensing may be employed as a localized, non-invasive surrogate to TEER electrodes used in cell cultures. Thus far, bioimpedance has only been implemented in esophagogastroduodenoscopy (EGD) due to the need for external electronics connections. In this work, we develop a novel, noise-resilient Bluetooth-enabled ingestible device for the continuous, non-invasive measurement of intestinal mucosal “leakiness.” As a proof-of-concept, we validate wireless impedance readout on excised porcine tissues in motion. Through an animal study, we demonstrate how the device exhibits altered impedance response to tight junction dilation induced on mice colonic tissue through calcium-chelator exposure. Device measurements are validated using standard benchtop methods for assessing mucosal permeability.