bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pemanfaatan Tepung Bekatul Sebagai Substitusi Bahan Pembuatan Stik Bawang
Authors: Rahmawati Fajar Tri , Putri Meddiati Fajri 
Published: March 2024

Stick is one of cakeâ€™s type that flat, long, like a cane, has a savory taste, has a crispy texture and the final process is through frying (Fransiska 2019). The aims of this study was to the determine the level of community interested for the experimental and brand stick on the stick product, make certain about the total food fiber content in the experimental stick, and calculate the selling price in the experimental sticks. The research method used is a descriptive analysis of the percentage using microsoft excel aplications, laboratory tests to determine the total nutritional content of food fiber using AOAC gravimetry, and calculating the selling price using the Break Event Point (BEP) analysis. The results showed that the most preferred brand was brand B. Laboratory test results of the average total food fiber content in sticks sequentially showed that bran flour substitution was 0% (9,66%), 6% (9,94%), 8% (16,07%) and 10% (17,87%). The results of the calculation of Break Event Point (BEP) on the stick with a 10% substitution of bran flour with sales of Rp.70.794.800 and can be reached in 191 days.
Reducing Antibiotic Duration for Uncomplicated UTI in the Pediatric Emergency Department
Authors: Kooner Gagandeep K. , Bass Marissa , Saroha Vivek , Gonzalez P.J. , Jain Shabnam 
Published: March 2024

BACKGROUND
Short-duration (3–5 days) antibiotic treatment of uncomplicated urinary tract infection (uUTI) in children &gt;24 months of age is equivalent to longer-duration antibiotic treatment, with added benefits of antibiotic stewardship. At our pediatric emergency department (ED), 13% of 5- to 18-year-old patients discharged with uUTI received ≤5 days of antibiotics. We aimed to increase short-duration prescriptions in patients with uUTI from 13% to &gt;50% over 12 months.

METHODS
This quality improvement project was conducted from January 2021 to August 2022. Complicated UTI was excluded. Interventions included education, practice feedback, and electronic health record changes. The outcome measure, the proportion of children treated with a short antibiotic duration, was studied by using p-charts. Antibiotic days saved were calculated. Revisits with UTI within 14 days of confirmed uUTI treated with short-duration antibiotics (balancing measure) were analyzed by using Fisher’s exact test.

RESULTS
In 1292 (n = 363 baseline, 929 post-intervention) eligible patients treated for uUTI, shorter antibiotic duration increased from 13% to 91%. We met our 50% aim within 2 months, with continued improvement leading to an additional centerline shift. Consequently, 2619 antibiotic days were saved. Two of 334 (0.6%) patients returned (P = NS) within 14 days of the index visit with a culture-positive uUTI.

CONCLUSIONS
By using education, feedback, and electronic health record changes, we decreased antibiotic duration in children discharged from the ED for uUTI without a significant increase in return visits with UTI. These interventions can be expanded to wider age groups and other outpatient settings.
A lived experience or a reason? From an ethics debate to contemporary culture
Authors: Hołub Grzegorz 
Published: March 2024

Karol Wojtyła’s debate with Max Scheler is multi-faceted. One of the central issues here is the dispute over the role of a lived experience and a reason in the structure of moral action. What is the starting point for providing an answer to the moral appeal directed at the human person? Is it a lived experience of an axiological quality called ‘value’ or a rational reason in which the value experienced is only one of the elements? Scheler is essentially in favour of the former scenario: the value carries sufficient power to pull the subject into action. And while his efficacy does not completely disappear here, it is fundamentally dominated by the axiological content (and attraction) of the value. Wojtyła takes a critical view of the German philosopher’s position, and states its inadequacy in the formation of mature moral action. A lived experience of a value is important, but it is not enough. The axiological experience moves the person, and contains an extraordinary force motivating one to undertake a specific act. However, without the participation of reason, it can be misguided and even inadequate. A person has to visualise, and to some extent objectivise the lived value for it to become the object of rational evaluation. Wojtyła’s dispute with Scheler is not just a marginal discussion between two European thinkers, within the hermetic philosophical debate of the 20th century. Indeed, it is part of the perennial questions as to what morality is, what role it plays in human life, and to what extent human beings influence the realisation of moral good and evil. The debate can also be a kind of lens affording a better view of the essence of contemporary disputes concerning both morality and culture. The diminishing and marginalisation of reason (especially in the strong, metaphysical version) in various spheres of life is striking. The tension between the culture of feeling and the culture of thinking is discernible and must prompt a debate. Karol Wojtyła shows what shape such a debate could take, and that it could be enriching for the entirety of contemporary culture.
Searching for Human Dignity: The Anthropological Dimension of Moral Teachings of Benedict XVI
Authors: Kluz Marek 
Published: March 2024

Shaping the Christian vision of moral life, Pope Benedict XVI referred to the anthropology centred around the Biblical vision of man. The first and fundamental thesis of the revealed anthropology is the truth about the dignity of a human person. Nevertheless, in today’s world one can observe certain symptoms of the lack of respect for self-dignity and dignity of other people. Being aware of this fact, in his teachings, Benedict XVI pointed out the value of human dignity; he promoted it and presented a genuine vision of personal dignity. Man and his dignity was the first principle, “so to say heart and soul” of the moral teachings of Pope Benedict XVI.
Social Media and Body Image from the Perspective of Secondary School Youth
Authors: Niklová Miriam , Zošáková Karina 
Published: March 2024

The study aimed to map the prevalence of social media disorder in secondary school youth. We used an abbreviated version of the Social Media Disorder Scale (SMD) and the Body Shape Questionnaire (BSQ-16B). The reliability of the questionnaires used in the research, indicates that they have sufficient internal consistency. A total of 637 re-respondents participated in the study. Their ages ranged from 15 to 19 years (AM=16.63). The results of the study showed social media impairment in 11.1% of the respondents, confirming a statistically significant difference in terms of the gender of the adolescents in favour of girls, and in terms of the degree of concern about their appearance, in favour of those who are more concerned about their appearance. Furthermore, a statistically significant difference in the degree of concern about their appearance in terms of gender, was confirmed in favour of girls.
Volunteering and Catholicism in Europe. The Inside Perspective Part 2: Empirical
Authors: Sadlon Wojciech , Rymsza Marek 
Published: March 2024

In the paper we analyse the social activity practices of Catholic persons, as a set of individual and collective action emerging from the Catholic identity and – to more or less extent – structuralised under the Church-related formal non-profit initiatives. The purpose of the study is to clarify: (1) to what extent the Catholic unpaid social activities of different kinds could be classified as forms of volunteering and (2) to what extent the third sector definitions of volunteering are included in specific Catholic activities. Three tendencies have been observed with respect to not including religion-oriented volunteering in voluntary studies. Firstly, while using tools for collecting data adequate for the secular world, researchers face methodological difficulties to successfully cover social activities organized in parishes and congregations. Secondly, a reductionist approach reflects the ideological-rooted tendency to treat religion as a matter of private life. Thirdly, some religious-based entities tend to keep social activities of the believers within the Church-related circle. From the Catholic perspective, volunteer engagement represents an important aspect of faith-based every day activities, the so-called lived religion. At the same time, social engagement of believers provided within the Church-related entities, as well as outside them, usually fulfils all main features of volunteering. The relation between volunteering and religion is to be referred not only to the general position of faith-based and religious organizations in the public sphere, but also to the embeddedness of religious life in the society, as in fact both religion and volunteering are categories social per se. We illustrate our reflection on volunteering and Catholicism by presenting empirical evidence from the 2018 panel expert research among representatives of 29 Catholic Bishops Conferences across Europe.
La giurisprudenza come fonte del diritto canonico Jurisprudence as a Source of Law
Authors: Michowicz Przemysław 
Published: March 2024

Starting with such a provocative title, the essay aims to answer the question of whether jurisprudence can be considered as a source of law in the canonical judicial system. In order to achieve the objectives of the present work, it is proposed not to observe a traditional path followed by those who interpret the provision of canon 19 of the current Code of Canon Law, but rather to consider jurisprudential creativity which represents, in its various manifestations, an unavoidable feature of legal experience. This premise helps to reconsider the source concept of law and systematizes the role of jurisprudential doctrine in the hierarchy of sources in the canonical legal system.
Dampak Kebijakan Publik Pembatasan Sosial Berskala Besar (PSBB) Terhadap Hak Konstitusional Warga Negara Saat Krisis Pandemi COVID-19
Authors: Safira Nur Rizqya  
Published: March 2024

Indonesia adalah salah satu negara yang terkena dampak dari pandemi COVID-19. Dengan menaiknya angka kasus positif di Indonesia, pemerintah mengambil langkah untuk menerapkan kebijakan Pembatasan Sosial Berskala Besar atau PSBB. Pemerintah disisi lain juga wajib memberikan perlindungan kepada masyarakat untuk mencegah dan menangani kasus COVID-19 sesuai dengan hak konstitusional yang terdapat dalam Undang-Undang Dasar Negara Republik Indonesia Tahun 1945.
Kajian penelitian ini merupakan studi dengan menggunakan metode kualitatif deskriptif yang ditinjau dari data kepustakaan tentang implementasi kebijakan publik dengan teori implementasi kebijakan publik.
Hasil penelitian menunjukkan bahwa dampak kebijakan publik Pembatasan Sosial Berskala Besar (PSBB) yang diterapkan oleh pemerintah Indonesia selama masa pandemi COVID-19 ini tidak efektif, dan bila dihubungkan dengan hak konstitusional warga negara, efektivitas dari berbagai kebijakan yang terkait dengan Pembatasan Sosial Berskala Besar (PSBB) akan berkurang karena masyarakat akan merasa tidak dilindungi undang-undang dan hukum. Adapun langkah efektif yang ditemukan antara lain dengan memperjelas informasi yang beredar tentang pandemi maupun tentang hak dan kewajiban antara pemerintah dan warga negara dalam kebijakan semasa pandemi COVID-19, dan adanya sinkronisasi dan transparansi antara pemerintah daerah dan pusat.
Pure sleep seizures: risk of seizures while awake
Authors: Fernández Lorena Benavente , Salas‐Puig Javier 
Published: March 2024

ABSTRACT

Purpose
To estimate the risk of seizures while awake in pure sleep epilepsies ‐ a long follow‐up study.

Methods
Fifty five patients (60% male), with pure sleep epilepsy were followed up for at least ten years. Patients younger than 18 years of age were excluded. The primary endpoint was the occurrence of seizures while awake, after a period of 10 years or longer suffering from pure sleep seizures.

Results
The duration of the pure sleep seizures ranged from 10 to 67 years (median 22). The patients had been followed in our Department for a mean of 12 years. Patients' ages ranged from 18 to 88 years (median 50); 44% of patients suffered from apparently generalized seizures. Epilepsy was considered undetermined in 38.2%, focal cryptogenic in 38.2%, and focal symptomatic in 21.8%. There was a single case of idiopathic generalized epilepsy. In the last evaluation, 35 patients were on monotherapy and two were not receiving treatment. Seizure frequency was < 1/year in 65.5%; 1‐10/year in 14.5%; > 1/month in 9.1%. Seventeen patients (30.9%) had suffered one or more seizures while awake. Multivariate analysis showed that sudden withdrawal of treatment (p < 0.032) and polytherapy (p < 0.18) were associated with an increased risk of seizures while awake.

Conclusions
In spite of a small number of seizures and good response to monotherapy, a third of the patients studied suffered seizures while awake. The significant risk factors were sudden withdrawal of treatment and polytherapy.
Unilateral polymicrogyria with ipsilateral cerebral hemiatrophy: a distinct syndrome?
Authors: Kuchukhidze G. , Unterberger I. , Dobesberger J. , Embacher N. , Walser G. , Luef G. , Koppelstaetter F. , Gotwald Th. , Bauer G. , Felber S.T. , Trinka E. 
Published: March 2024

ABSTRACT

Introduction
There are sporadic reports of unilateral polymicrogyria with ipsilateral hemiatrophic cerebri associated with epilepsy, focal neurological deficit and mental retardation. The mechanisms which cause this condition are not well understood. The aim of our study was to delineate further, clinical and neuroimaging features of this malformation of cortical development and to explore its possible etiological background.

Patients and methods
Four patients (two males and two females), aged from 23 to 31 years (mean age range 27.5 years) were evaluated. Subjects underwent clinical, electrophysiological, neuropsychological and high resolution magnetic resonance imaging assessment.

Results
No significant perinatal event or exposure to intrauterine infection was noted. None suffered from birth asphyxia or ischemic injury. The parents of two patients were first cousins. Every subject had delayed developmental milestones, mental disability and congenital, non‐progressive, spastic hemiparesis. They had epilepsy with seizure‐onset ranging from three months to 17 years (mean 6.8 years); two had intractable seizures. In all patients, unilateral, right‐sided polymicrogyria was associated with ipsilateral cerebral hemiatrophy. Polymicrogyria involved mainly anterior perisylvian areas; occipital regions were relatively spared.

Conclusion
The evaluated patients showed homogenous clinical and neuroimaging characteristics. We support the idea that the disorder could constitute a clinical entity with an underlying genetic cause.
Chronic PLEDs with transitional rhythmic discharges (PLEDs‐plus) in remote stroke
Authors: Téllez‐Zenteno José F. , Pillai Sylaja N. , Hill Michael D. , Pillay Neelan 
Published: March 2024

ABSTRACT

Background.
Periodic lateralized epileptiform discharges (PLEDs) are a rare phenomenon in electroencephalography, occurring in acute structural brain lesions. In general, PLEDs appear transiently in acute lesions, but a few reports have described persistent PLEDs in chronic lesions.
Case report.
An 86‐year‐old female was admitted, in 1999, with a left MCA stroke associated with right hand focal motor seizures. The first EEG in February of 2002 showed PLEDs over the left hemisphere associated with rhythmic discharges (PLEDs‐plus). The patient was admitted on a second occasion in 2003 because of three sequential seizures and the EEG showed a similar pattern. Finally in 2006, the patient was admitted again because of sequential complex partial seizures and an EEG showed the same PLEDS‐plus pattern as the EEGs of 2002 and 2003.
Discussion.
We report an unusual case of chronic PLEDs associated with rhythmic discharges in a patient with recurrent seizures and remote stroke.
Spinal algetic‐tonic seizures manifesting as paroxysmal “positive” Brown‐Séquard syndrome
Authors: Kirchner Anne , Poepel Annkathrin , Hantsch Matthias , Urbach Horst , Elger Christian E. , Bien Christian G. 
Published: March 2024

ABSTRACT
We report on a patient suffering from symptomatic spinal attacks in the form of a paroxysmal “positive” (algetic‐tonic) Brown‐Séquard syndrome. A cervical cord lesion, presumably inflammatory‐demyelinating in origin, was identified as the morphological correlate of these attacks. Their pathogenesis is discussed in the light of similar case reports from the literature. For the first time, this rare type of seizure is published with a video documentation. It may deserve consideration in the differential diagnosis of otherwise unexplained paroxysmal events that present in an “epileptic” manner.

[Published with video sequences]
Genetics of epilepsy: Epilepsy Research Foundation workshop report
Authors: Sisodiya Sanjay , Cross J. Helen , Blümcke Ingmar , Chadwick David , Craig John , Crino Peter B. , Debenham Paul , Delanty Norman , Elmslie Frances , Gardiner Mark , Golden Jeffrey , Goldstein David , Greenberg David A. , Guerrini Renzo , Hanna Michael , Harris John , Harrison Paul , Johnson Michael R. , Kirov George , Kullman Dimitri M. , Makoff Andrew , Marini Carla , Nabbout Rima , Nashef Lina , Noebels Jeffrey L. , Ottman Ruth , Pirmohamed Munir , Pitkänen Asla , Scheffer Ingrid , Shorvon Simon , Sills Graeme , Wood Nicholas , Zuberi Sameer 
Published: March 2024

ABSTRACT
The Sixth Epilepsy Research Foundation workshop, held in Oxford in March 2006, brought together basic scientists, geneticists, epidemiologists, statisticians, pharmacologists and clinicians to consider progress, issues and strategies for harnessing genetics to improve the understanding and treatment of the epilepsies. General principles were considered, including the fundamental importance of clear study design, adequate patient numbers, defined phenotypes, robust statistical data handling, and follow‐up of genetic discoveries. Topics where some progress had been made were considered including chromosomal abnormalities, neurodevelopment, hippocampal sclerosis, juvenile myoclonic epilepsy, focal cortical dysplasia and pharmacogenetics. The ethical aspects of epilepsy genetics were reviewed. Principles and limitations of collaboration were discussed. Presentations and their matched discussions are produced here. There was optimism that further genetic research in epilepsy was not only feasible, but might lead to improvements in the lives of people with epilepsy.
Maternal and fetal outcome in women with epilepsy associated with neurocysticercosis
Authors: Pandian Jeyaraj Durai , Venkateswaralu K. , Thomas Sanjeev V. , Sarma P.S. 
Published: March 2024

ABSTRACT

Aim
We wanted to characterize the clinical profile and outcome of pregnancy in women with epilepsy due to neurocysticercosis (NCC) enrolled in the Indian Registry of Epilepsy and Pregnancy (IREP).

Methods
We identified all women with NCC in the IREP between January 2000 and September 2005. Age‐ and parity‐matched patients without NCC were identified from the respective centers of IREP for comparison. Statistical analysis was performed using SPSS version 11.

Results

There were 30 women with NCC (mean age 24.3 ± 4 years) among 1071 registrations in the IREP. All the patients had NCC prior to the pregnancy. Fourteen (47%) NCC patients had calcified lesions and 16 (53%) had ring lesions in a CT scan of the brain. Compared to women without NCC, the NCC group had later age‐at‐onset of seizures (20.7 ± 4.4 years, p = 0.008) and epilepsy (21.1 ± 5.2 years, p = 0.01). They were more likely to have partial seizures (70%
versus
30%, p = 0.002), an EEG without epileptiform abnormalities (50%
versus
100%, p = 0.01), and better control of seizures before (47%
versus
3%, p = 0.001) and during pregnancy (33%
versus
10%, p = 0.02). Maternal and neonatal complications did not differ between the groups.

Conclusions
NCC is an uncommon cause of epilepsy in pregnant women enrolled in IREP. To be noted, as a limitation of our study, that the IREP is a hospital‐based registry, which may not reflect global epilepsy characteristics of the community. The maternal and fetal outcome for NCC patients was not different from those women without NCC.
Ictal singing due to left mesial temporal sclerosis
Authors: Kuscu Demet Yandim , Kayrak Nalan , Karasu Aykut , Gul Gunay , Kirbas Dursun 
Published: March 2024

ABSTRACT
Simple ictal or interictal automatisms are commonly seen in epilepsy, whereas complex automatisms are rare. Simple ictal vocalizations or appendicular automatisms have been reported to be due to mesial temporal lobe epilepsy. However, seizure‐associated singing and dancing is very rare. We report a seventeen‐year‐old patient with ictal singing and rhythmic swinging of the arms as a dancing gesture. The video‐EEG recording showed ictal left temporal lateralization and neuropathology confirmed left mesial temporal sclerosis.

[Pusblished with video sequences]
.
Application of the 2001 diagnostic scheme and the 2006 ILAE report of seizure and epilepsy: a feedback from the clinical practice of adult epilepsy
Authors: Kinoshita Masako , Takahashi Ryosuke , Ikeda Akio 
Published: March 2024

ABSTRACT

Purpose
To clarify the clinical validity and feasibility of the diagnostic scheme for seizures and epilepsy proposed by the International League Against Epilepsy (ILAE) in 2001 (the 2001 Scheme) and the report of the ILAE classification core group in 2006 (the 2006 Report).

Methods
One hundred consecutive patients with epilepsy who visited the Neurology Clinic (Group 1) and 100 patients with intractable epilepsy who had undergone prolonged scalp video‐EEG monitoring (Group 2) in Kyoto University Hospital were enrolled. The 2001 Scheme (Axis 1 to 4) and the 2006 Report (seizure types and epileptic syndromes) were applied to Group 1. Axis 1 was applied to Group 2 to evaluate the diversity of seizure semiology.

Results
Group 1 demonstrated 145 seizures of different types (generalized tonic‐clonic seizures: 23%, complex partial seizures (CPS): 29%, simple partial seizures: 21% and secondarily generalized tonicclonic seizures: 21% according to the 1981 classification. In Axis 1 (ictal phenomenology) of the 2001 scheme, 184 and 333 items were listed in Groups 1 and 2, respectively, and seizure semiology was described independent of EEG findings. However, there was duplications or discordance among the items. In Axis 2 (seizure types) of Group 1, 62% and 26% of CPS were further labeled as focal motor or sensory seizures, respectively; the remainder (24%) did not meet inclusion criteria for any category. In Axis 3 (epilepsy syndromes), 94% of patients were sorted, and familial temporal lobe epilepsy was added. Axis 4 described detailed etiology. Application of seizure types of the 2006 Report required consideration of ictal phenomenology to determine spread patterns. Epileptic syndromes of the 2006 Report were assignable to 70% of patients.

Conclusions
It is important to achieve intra‐ and inter‐axial accordance for the establishment of a more practical diagnostic scheme, which may provide a more useful tool for the diagnosis of less obvious aspects of epilepsy.