bluuebunny/crossref_metadata_2025_split huggingface dataset:
Synthesis of Thymine Polyoxin C (VIII) by Using L‐Threonine Aldolase‐Catalyzed Reaction
Authors: Nishiyama Toshihiro , Mohile Swapnil Surendra , Kajimoto Tetsuya , Node Manabu 
Published: October 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
New Aliphatic Alcohol and Ester Constituents from Rice Hulls of Oryza sativa
Authors: Chung Ill‐Min , Ali Mohd , Chun Se‐Chul , Jin Cheng‐Wu , Cho Dong‐Ha , Hong Seung‐Beom , Ahmad Ateeque 
Published: October 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Syntheses of Retipolide E (I) and Ornatipolide (II), 14‐Membered Biaryl‐Ether Macrolactones from Mushrooms.
Authors: Ingerl Andrea , Justus Karl , Hellwig Veronika , Steglich Wolfgang 
Published: October 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Formal Chemoselective Synthesis of Leucascandrolide A.
Authors: Ferrie Laurent , Reymond Sebastien , Capdevielle Patrice , Cossy Janine 
Published: October 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Isolation, Structure Elucidation and Activity of an Unknown Impurity of Amphotericin B.
Authors: Li Jin , Zhu Hui‐Qin , Li Jing‐Yun , Jin Shao‐Hong , Hu Chang‐Qin 
Published: October 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Abyssomicin E, a Highly Functionalized Polycyclic Metabolite from Streptomyces Species.
Authors: Niu Xue‐Mei , Li Sheng‐Hong , Goerls Helmar , Schollmeyer Dieter , Hilliger Matthias , Grabley Susanne , Sattler Isabel 
Published: October 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Fumimycin: A Peptide Deformylase Inhibitor with an Unusual Skeleton Produced by Aspergillus fumisynnematus.
Authors: Kwon Yun‐Ju , Sohn Mi‐Jin , Zheng Chang‐Ji , Kim Won‐Gon 
Published: October 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Synthesis and Relative Stereochemistry of the A‐ and F‐Rings of Goniodomin A.
Authors: Fujiwara Kenshu , Naka Jota , Katagiri Takahiro , Sato Daisuke , Kawai Hidetoshi , Suzuki Takanori 
Published: October 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Elloxazinones A and B, New Aminophenoxazinones from Streptomyces griseus Acta 2871
Authors: Graf Ellen , Schneider Kathrin , Nicholson Graeme , Stroebele Markus , Jones Amanda L. , Goodfellow Michael , Beil Winfried , Suessmuth Roderich D. , Fiedler Hans‐Peter 
Published: October 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Serialynic Acid, a New Phenol with an Isopentenyne Side Chain from Antrodia serialis
Authors: Kokubun Tetsuo , Irwin Dianne , Legg Mike , Veitch Nigel C. , Simmonds Monique S. J. 
Published: October 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Iriomoteolide‐1a, a Potent Cytotoxic 20‐Membered Macrolide from a Benthic Dinoflagellate Amphidinium Species.
Authors: Tsuda Masashi , et al. et al. 
Published: October 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Chemical Constituents from Piper marginatum Jacq. (Piperaceae) — Antifungal Activities and Kinetic Resolution of (RS)‐Marginatumol by Candida antarctica Lipase (Novozym 435).
Authors: Reigada Juliana B. , Tcacenco Celize M. , Andrade Leandro H. , Kato Massuo J. , Porto Andre L. M. , Lago Joao Henrique G. 
Published: October 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Iromycins: A New Family of Pyridone Metabolites from Streptomyces sp. Part 2. Convergent Total Synthesis.
Authors: Shojaei Heydar , Li‐Boehmer Zhen , von Zezschwitz Paultheo 
Published: October 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Alcohol‐Assisted CVD of Silver Using Commercially Available Precursors.
Authors: Bahlawane Naoufal , Premkumar Peter Antony , Brechling Armin , Reiss Guenter , Kohse‐Hoeinghaus Katharina 
Published: October 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Microbial Transformations of Actinides in Transuranic‐ and Mixed‐wastes: Implications for Radioactive‐waste Disposal
Authors: Francis A. J. 
Published: October 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Ultra‐Low Catalyst Loading as a Concept in Economical and Sustainable Modern Chemistry: The Contribution of Ferrocenylpolyphosphane Ligands
Authors: Hierso Jean‐Cyrille , Beauperin Matthieu , Meunier Philippe 
Published: October 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Recent Advances in the Chemistry of α,β‐Unsaturated Trifluoromethylketones
Authors: Druzhinin Sergey V. , Balenkova Elizabeth S. , Nenajdenko Valentine G. 
Published: October 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Regioselective (Site‐Selective) Functionalization of Unsaturated Halogenated Nitrogen, Oxygen and Sulfur Heterocycles by Pd‐Catalyzed Cross‐Couplings and Direct Arylation Processes
Authors: Fairlamb Ian J. S. 
Published: October 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Halogen Dance Reactions — A Review
Authors: Schnuerch Michael , Spina Markus , Khan Ather Farooq , Mihovilovic Marko D. , Stanetty Peter 
Published: October 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Applications of and Alternatives to π‐Electron‐Deficient Azine Organometallics in Metal‐Catalyzed Cross‐Coupling Reactions
Authors: Campeau Louis‐Charles , Fagnou Keith 
Published: October 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
The Fascinating Construction of Pyridine Ring Systems by Transition Metal Catalyzed [2 + 2 + 2] Cycloaddition Reactions
Authors: Heller Barbara , Hapke Marko 
Published: October 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Intermolecular Reactions of Electron‐Rich Heterocycles with Copper and Rhodium Carbenoids
Authors: Davies Huw M. L. , Hedley Simon J. 
Published: October 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Intramolecular Aminopalladation of Alkenes as a Key Step to Pyrrolidines and Related Heterocycles
Authors: Minatti Ana , Muniz Kilian 
Published: October 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Heterocycle Synthesis by Copper Facilitated Addition of Heteroatoms to Alkenes, Alkynes and Arenes
Authors: Chemler Sherry R. , Fuller Peter H. 
Published: October 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Design, Synthesis, and Biological Activity of Unnatural Enediynes and Related Analogues Equipped with pH‐Dependent or Phototriggering Devices
Authors: Kar Moumita , Basak Amit 
Published: October 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Nonpeptidic Ligands for Peptide‐Activated G Protein‐Coupled Receptors
Authors: Blakeney Jade S. , Reid Robert C. , Le Giang T. , Fairlie David P. 
Published: October 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Rubromycins: Structurally Intriguing, Biologically Valuable, Synthetically Challenging Antitumor Antibiotics
Authors: Brasholz Malte , Soergel Sebastian , Azap Cengiz , Reissig Hans‐Ulrich 
Published: October 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Role of Modified Nucleosides in the Translation Function of tRNAs from Extreme Thermophilic Bacteria and Animal Mitochondria.
Authors: Watanabe Kimitsuna 
Published: October 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Biosynthesis of Characteristic Lipid—Core of Archaea — Understanding for the Adaptation of Archaea to Harsh Environment and Toward a New Design for Lipid Molecules
Authors: Yamauchi Noriaki 
Published: October 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Supramolecular Nanocarriers Integrated with Dendrimers Encapsulating Photosensitizers for Effective Photodynamic Therapy and Photochemical Gene Delivery
Authors: Nishiyama Nobuhiro , Jang Woo‐Dong , Kataoka Kazunori 
Published: October 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Recent Progress and Applications for Metallodendrimers
Authors: Hwang Seek‐Ho , Shreiner Carol D. , Moorefield Charles N. , Newkome George R. 
Published: October 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Structural Determination of the ComX Pheromone: Synthetic Studies on ComXRO‐E‐2 Pheromone and ComXRO‐E‐2 Peptides Containing Modified Tryptophan Residue with a Geranyl Group
Authors: Okada Masahiro , Sakagami Youji 
Published: October 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Haptoglobin and posttranslational glycan‐modified derivatives as serum biomarkers for the diagnosis of nonsmall cell lung cancer
Authors: Hoagland Luke F. M. , Campa Michael J. , Gottlin Elizabeth B. , Herndon James E. , Patz Edward F. 
Published: October 2007

AbstractBACKGROUND.The purpose was to evaluate the clinical utility of serum haptoglobin (Hp) and posttranslational glycan modifications of Hp for the diagnosis of nonsmall cell lung cancer (NSCLC).METHODS.Serum proteins from patients with a new diagnosis of NSCLC and age‐ and sex‐matched controls without cancer were compared using 2‐dimensional difference gel electrophoresis (2D‐DIGE). Four of the differentially expressed gel spots were identified as the β chain of Hp. Immunoblots confirmed sialyl and fucosyl group posttranslational modifications (PTMs) of Hp. Serum enzyme‐linked immunosorbent assays (ELISAs) for total Hp, sialylated Hp (SAHp), and fucosylated Hp (FHp) were designed, and levels of each were measured in an independent sample set of 74 patients. Receiver operating characteristic (ROC) analysis assessed the clinical diagnostic utility of each marker.RESULTS.Statistically significant differences between lung cancer patients and matched controls were found by ELISA for Hp (P < .002), SAHp (P < .001), and FHp (P < .04). ROC analysis determined an area under the curve (AUC) of 0.754 for Hp, 0.740 for SAHp, and 0.794 for FHp. In addition, serum concentrations correlated with stage; Hp (r = 0.388; P = .018), SAHp (r = 0.300; P = .072), and FHp (r = 0.363; P = .027).CONCLUSIONS.Hp and 2 of its glycoforms, SAHp and FHp, are potentially useful in the clinical diagnosis of NSCLC. The markers increase with stage, suggesting they may also be useful in stratifying patients at presentation and in following patients after treatment. Cancer 2007. © 2007 American Cancer Society.
Frequency, risk factors, and trends for venous thromboembolism among hospitalized cancer patients
Authors: Khorana Alok A. , Francis Charles W. , Culakova Eva , Kuderer Nicole M. , Lyman Gary H. 
Published: October 2007

AbstractBACKGROUND.Venous thromboembolism (VTE) contributes to morbidity and mortality in cancer patients and is a frequent complication of anticancer therapy. In the current study, the frequency, risk factors, and trends associated with VTE were examined among hospitalized cancer patients.METHODS.A retrospective cohort study was conducted using the discharge database of the University HealthSystem Consortium. This included 1,824,316 hospitalizations between 1995 and 2003 at 133 U.S. medical centers.RESULTS.Among 1,015,598 cancer patients, 34,357 (3.4%) were diagnosed with deep venous thrombosis and 11,515 with pulmonary embolism (PE) (1.1%) for an overall VTE rate of 4.1%. Subgroups of cancer patients with the highest rates included black ethnicity (5.1% per hospitalization) and those receiving chemotherapy (4.9%). Sites of cancer with the highest rates of VTE included pancreas (8.1%), kidney (5.6%), ovary (5.6%), lung (5.1%), and stomach (4.9%). Among hematologic malignancies, myeloma (5%), non‐Hodgkin lymphoma (4.8%), and Hodgkin disease (4.6%) had the highest rates of VTE. The rate of VTE increased by 28%, secondary to a near‐doubling of PE rates from 0.8% to 1.5% (P < .0001). Among patients receiving chemotherapy, the rates of VTE rose from 3.9% to 5.7%, an increase of 47% (P < .0001). In multivariate analysis, risk factors associated with VTE included age ≥65 years, female sex, black ethnicity, use of chemotherapy, primary site of cancer, presence of comorbidities, and year of admission.CONCLUSIONS.VTE, particularly PE, is an increasingly frequent complication of hospitalization in cancer patients. Patients with black ethnicity, specific sites of cancer, or those receiving chemotherapy are disproportionately at risk. Cancer 2007. © 2007 American Cancer Society.
A phase II evaluation of goserelin and bicalutamide in patients with ovarian cancer in second or higher complete clinical disease remission
Authors: Levine Douglas , Park Kay , Juretzka Margrit , Esch Julie , Hensley Martee , Aghajanian Carol , Lewin Sharyn , Konner Jason , Derosa Felicia , Spriggs David , Iasonos Alexia , Sabbatini Paul 
Published: October 2007

AbstractBACKGROUND.The current study was conducted to determine the effect of goserelin and bicalutamide on progression‐free survival (PFS) in patients with epithelial ovarian cancer who were in second or greater complete disease remission.METHODS.Patients received bicalutamide at a dose of 50 mg orally daily and goserelin at a dose of 3.6 mg subcutaneously every 4 weeks. CA 125 was obtained monthly, with computed tomography performed every 3 months. Correlative studies included serum luteinizing hormone, follicle‐stimulating hormone, vascular endothelial growth factor, free testosterone, and androstenedione and the germline polymorphisms CYP19A1 and androgen receptor.RESULTS.Between October of 2000 and October of 2002, 35 patients were enrolled. Three patients (9%) received therapy at the time of first disease remission and were removed from the study, and 1 patient (3%) was removed for liver function test abnormalities. The most frequent toxicities were grade 1 alkaline phosphatase (54%), fatigue (57%), and hot flashes (42%) based on the National Cancer Institute common toxicity scale, version 2.0. The PFS for patients receiving protocol therapy in second disease remission (21 patients) was 11.4 months (95% confidence interval [95% CI], 10.2–12.6 months). The PFS for patients receiving protocol therapy in third or fourth disease remission (11 patients) was 11.9 months (95% CI, 10.8–14.1 months). The percentage of patients remaining in second disease remission at given times are: 100% at 3 months, 100% at 6 months, 72% at 9 months, 47% at 12 months, 28% at 15 months, 22% at 18 months, 19% at 21 months, and 13% at 24 months. There were no associations noted between androgen receptor repeat number, genotype, allelotype, or haplotypes and PFS.CONCLUSIONS.The use of goserelin and bicalutamide did not appear to prolong PFS in patients with epithelial ovarian cancer in second or greater complete disease remission. The number of patients in disease remission at given time points may serve as a clinical trial endpoint for future studies of consolidation therapy. Cancer 2007. © 2007 American Cancer Society.
Role for para sodium channel gene 3′ UTR in the modification of Drosophila seizure susceptibility
Authors: Song Juan , Tanouye Mark 
Published: October 2007

AbstractVoltage‐gated sodium channel genes are highly regulated at the level of transcription or translation. In this study, we have utilized the combination of genetic, electrophysiological, and molecular analyses to identify a 7‐kb 3′‐untranslated region (UTR) of the Drosophila para sodium channel gene. Disruption of this segment by P‐element insertion causes reduction of para primary transcript, but not Rbp2 transcripts. The identification of this novel 3′‐UTR is based on a P‐insertion mutation called paraJS1, which was isolated from a P‐element mutagenesis screen for seizure suppressors in a Drosophila model of epilepsy. The paraJS1 mutation was identified 6845 bp downstream of the para gene, which resides in an intergenic region that lies between para and Rbp2 (RNA‐binding protein 2) genes. Interestingly, reverse‐transcription PCR showed that the region containing paraJS1 is substantially transcribed and this transcribed region is associated with para coding region. We discussed possible mechanisms of how reduced transcription of the para gene or alterations in sodium channel subunit composition might be indicated by the paraJS1 mutation and implications for para 3′ UTR function. © 2007 Wiley Periodicals, Inc. Develop Neurobiol, 2007
Exogenous Hsc70, but not thermal preconditioning, confers protection to motoneurons subjected to oxidative stress
Authors: Robinson Mac B. , Taylor Anna R. , Gifondorwa David J. , Tytell Michael , Milligan Carolanne E. 
Published: October 2007

AbstractProper sensing of stress and the initiation of the stress response are critical to maintaining cell viability in response to noxious stimuli. Induction of the stress response prior to the exposure of a lethal stress (preconditioning) can be protective. Heat shock proteins (Hsps), the main products of the stress response, are considered to be responsible for this protective effect. Most cells readily initiate a stress response, but some neuronal phenotypes, including motoneurons (MNs), have a diminished capacity to do so. We have found that, given a proper stimulus, MNs can execute a heat stress response; but, it does not protect them from death caused by hydrogen peroxide (H2O2) induced oxidative stress, despite inhibiting H2O2‐induced caspase activation. Conversely, we demonstrate that incubation with the heat shock cognate 70 (Hsc70) protein prior to oxidative insult can protect MNs from oxidative stress. This survival promoting effect may be mediated through the substrate binding domain (SBD) of Hsc70. Our data suggest that stress preconditioning may not be beneficial to MNs, but that pharmacological interventions and alternative means of acquiring components of the stress response are an effective means of ameliorating lethal stress in MNs and may be potentially useful therapeutically in preventing pathological MN loss. © 2007 Wiley Periodicals, Inc. Develop Neurobiol, 2008
The zebrafish ennui behavioral mutation disrupts acetylcholine receptor localization and motor axon stability
Authors: Saint‐Amant Louis , Sprague Shawn M. , Hirata Hiromi , Li Qin , Cui Wilson W. , Zhou Weibin , Poudou Olivier , Hume Richard I. , Kuwada John Y. 
Published: October 2007

AbstractThe zebrafish ennui mutation was identified from a mutagenesis screen for defects in early behavior. Homozygous ennui embryos swam more slowly than wild‐type siblings but normal swimming recovered during larval stages and homozygous mutants survived until adulthood. Electrophysiological recordings from motoneurons and muscles suggested that the motor output of the CNS following mechanosensory stimulation was normal in ennui, but the synaptic currents at the neuromuscular junction were significantly reduced. Analysis of acetylcholine receptors (AChRs) in ennui muscles showed a marked reduction in the size of synaptic clusters and their aberrant localization at the myotome segment borders of fast twitch muscle. Prepatterned, nerve‐independent AChR clusters appeared normal in mutant embryos and dispersed upon outgrowth of motor axons onto the muscles. Genetic mosaic analysis showed that ennui is required cell autonomously in muscle fibers for normal synaptic localization of AChRs. Furthermore, exogenous agrin failed to induce AChR aggregation, suggesting that ennui is crucial for agrin function. Finally, motor axons branched more extensively in ennui fast twitch muscles especially in the region of the myotome borders. These results suggest that ennui is important for nerve‐dependent AChR clustering and the stability of axon growth. © 2007 Wiley Periodicals, Inc. Develop Neurobiol, 2008