bluuebunny/crossref_metadata_2025_split huggingface dataset:
PERENCANAAN GAMBAR LISTRIK UNTUK RENOVASI KELISTRIKAN GEREJA “X” DI SURABAYA
Authors: Limanto James , Setiadji Julius Sentosa , Hosea Emmy 
Published: April 2024

Gereja “X” berencana melakukan renovasi sistem kelistrikan bangunan. Renovasi sistem kelistrikan tersebut bertujuan untuk mengganti dan menata ulang sistem kelistrikan di bangunan gereja. Sebelum merancang sistem kelistrikan bangunan terlebih dahulu dilakukan penataan sistem pencahayaan dengan bantuan software calculux indoor 5.0b untuk mensimulasikan sistem pencahayaan yang baru. Hasil simulasi menunjukkan pencahayaan pada rancangan baru sudah memenuhi standar SNI pencahayaan dengan rata – rata selisih keseluruhan ruangan sebesar 3,22%. Dalam pengerjaan rancangan sistem kelistrikan yang baru, terdapat 5 panel meliputi 1 LVMDP (Low Voltage Main Distribution Panel) dan 4 SDP (Sub Distribution Panel). Untuk SDP, panel A dan B mengatur beban penerangan dan stop kontak lantai 1 dan 2, panel C mengatur beban yang menyala pada malam hari, panel D mengatur beban air conditioner.
PERANCANGAN DAN PEMANTAUAN LOCKER MENGGUNAKAN KTM BERBASIS ESP8266
Authors: Rory Daniel Ignatius , Putro Iwan Handoyo , Khoswanto Handry 
Published: April 2024

Penelitian ini dilatarbelakangi oleh beberapa kasus dimana barang atau komponen hilang saat di rak lab kampus, beberapa kasus dimana salah satu proyek dari mahasiswa rusak karena ditinggal di rak lab kampus, ada juga beberapa kasus dimana barang yang dititipkan di lab tertinggal atau lupa akan barangnya. Hal ini menyebabkan kerugian pada pengguna rak serta kurangnya informasi asisten lab akan barang tersebut. Pada studi ini, penulis berusaha untuk membuat alat yang bisa berfungsi sebagai sistem keamanan locker dengan menggunakan RFID pada KTM mahasiswa. Alat ini bisa memantau penggunaan locker user, locker nomor berapa yang digunakan dan jam penggunaan locker. Proses pemantauan ini bisa lakukan oleh admin ataupun user itu sendiri. Pengujian dilakukan dengan 3 metode. Pertama, Pengujian hardware yang terdiri dari pengujian alat RFID tanpa dan menggunakan media penghalang. Kedua, pengujian software yang terdiri dari pengujian input, edit, tambah, hapus dan pengujian melakukan monitoring. Ketiga, pengujian sistem secara keseluruhan.
High‐order simulation of polymorphic crystallization using weighted essentially nonoscillatory methods
Authors: Hermanto Martin Wijaya , Braatz Richard D. , Chiu Min‐Sen 
Published: November 2008

AbstractMost pharmaceutical manufacturing processes include a series of crystallization processes to increase purity with the last crystallization used to produce crystals of desired size, shape, and crystal form. The fact that different crystal forms (known as polymorphs) can have vastly different characteristics has motivated efforts to understand, simulate, and control polymorphic crystallization processes. This article proposes the use of weighted essentially nonoscillatory (WENO) methods for the numerical simulation of population balance models (PBMs) for crystallization processes, which provide much higher order accuracy than previously considered methods for simulating PBMs, and also excellent accuracy for sharp or discontinuous distributions. Three different WENO methods are shown to provide substantial reductions in numerical diffusion or dispersion compared with the other finite difference and finite volume methods described in the literature for solving PBMs, in an application to the polymorphic crystallization of L‐glutamic acid. © 2008 American Institute of Chemical Engineers AIChE J, 2009
Convergent functional genomics of genome‐wide association data for bipolar disorder: Comprehensive identification of candidate genes, pathways and mechanisms
Authors: Le‐Niculescu H. , Patel S.D. , Bhat M. , Kuczenski R. , Faraone S.V. , Tsuang M.T. , McMahon F.J. , Schork N.J. , Nurnberger J.I. , Niculescu A.B. 
Published: November 2008

AbstractGiven the mounting convergent evidence implicating many more genes in complex disorders such as bipolar disorder than the small number identified unambiguously by the first‐generation Genome‐Wide Association studies (GWAS) to date, there is a strong need for improvements in methodology. One strategy is to include in the next generation GWAS larger numbers of subjects, and/or to pool independent studies into meta‐analyses. We propose and provide proof of principle for the use of a complementary approach, convergent functional genomics (CFG), as a way of mining the existing GWAS datasets for signals that are there already, but did not reach significance using a genetics‐only approach. With the CFG approach, the integration of genetics with genomics, of human and animal model data, and of multiple independent lines of evidence converging on the same genes offers a way of extracting signal from noise and prioritizing candidates. In essence our analysis is the most comprehensive integration of genetics and functional genomics to date in the field of bipolar disorder, yielding a series of novel (such as Klf12, Aldh1a1, A2bp1, Ak3l1, Rorb, Rora) and previously known (such as Bdnf, Arntl, Gsk3b, Disc1, Nrg1, Htr2a) candidate genes, blood biomarkers, as well as a comprehensive identification of pathways and mechanisms. These become prime targets for hypothesis driven follow‐up studies, new drug development and personalized medicine approaches. © 2008 Wiley‐Liss, Inc.
Chemical Strategies for Generating Protein Biochips
Authors: Jonkheijm Pascal , Weinrich Dirk , Schröder Hendrik , Niemeyer Christof M. , Waldmann Herbert 
Published: November 2008

AbstractProtein biochips are at the heart of many medical and bioanalytical applications. Increasing interest has been focused on surface activation and subsequent functionalization strategies for immobilizing these biomolecules. Different approaches using covalent and noncovalent chemistry are reviewed; particular emphasis is placed on the chemical specificity of protein attachment and on retention of protein function. Strategies for creating protein patterns (as opposed to protein arrays) are also outlined. An outlook on promising and challenging future directions for protein biochip research and applications is also offered.
The Azadirachtin Story
Authors: Veitch Gemma E. , Boyer Alistair , Ley Steven V. 
Published: November 2008

AbstractAzadirachtin has been the subject of intensive research within the scientific community ever since its isolation from the neem tree in 1968. There are now over 1000 publications relating to this natural product which cover all aspects of structural, biological and synthetic studies. Herein, we describe the worldwide synthesis efforts towards this fascinating molecule.
Progress and challenges in freshwater conservation planning
Authors: Nel Jeanne L. , Roux Dirk J. , Abell Robin , Ashton Peter J. , Cowling Richard M. , Higgins Jonathan V. , Thieme Michele , Viers Joshua H. 
Published: November 2008

Abstract
Freshwater ecosystems and their associated biota are among the most endangered in the world. This, combined with escalating human pressure on water resources, demands that urgent measures be taken to conserve freshwater ecosystems and the services they provide. Systematic conservation planning provides a strategic and scientifically defensible framework for doing this.
Pioneered in the terrestrial realm, there has been some scepticism associated with the applicability of systematic approaches to freshwater conservation planning. Recent studies, however, indicate that it is possible to apply overarching systematic conservation planning goals to the freshwater realm although the specific methods for achieving these will differ, particularly in relation to the strong connectivity inherent to most freshwater systems.
Progress has been made in establishing surrogates that depict freshwater biodiversity and ecological integrity, developing complementarity‐based algorithms that incorporate directional connectivity, and designing freshwater conservation area networks that take cognizance of both connectivity and implementation practicalities.
Key research priorities include increased impetus on planning for non‐riverine freshwater systems; evaluating the effectiveness of freshwater biodiversity surrogates; establishing scientifically defensible conservation targets; developing complementarity‐based algorithms that simultaneously consider connectivity issues for both lentic and lotic water bodies; developing integrated conservation plans across freshwater, terrestrial and marine realms; incorporating uncertainty and dynamic threats into freshwater conservation planning; collection and collation of scale‐appropriate primary data; and building an evidence‐base to support improved implementation of freshwater conservation plans.
Copyright © 2008 John Wiley & Sons, Ltd.
Problem‐solving test: A mutation causing cystic fibrosis
Authors: Szeberényi József 
Published: November 2008

AbstractTerms to be familiar with before you start to solve the test: cystic fibrosis, pedigree analysis, transmembrane protein, channel protein, polymerase chain reaction, primers, polyacrylamide gel electrophoresis, fluorescent DNA staining, autosomal vs. sex‐linked inheritance, recessive vs. dominant inheritance, homozygote, heterozygote, frame‐shift mutation, deletion.
Glucose as the sole metabolic fuel: The possible influence of formal teaching on the establishment of a misconception about energy‐yielding metabolism among students from Rio de Janeiro, Brazil
Authors: Luz Maurício R. M. P. , de Oliveira Gabriel Aguiar , de Sousa Cristiane Ribeiro , Da Poian Andrea T. 
Published: November 2008

AbstractEnergy‐yielding metabolism is an important biochemistry subject that is related to many daily experiences and health issues of students. An adequate knowledge of the general features of EYM is therefore important, both from an academic and social point of view. In a previous study, we have shown that high‐school students present the misconception that carbohydrates, especially glucose, are the sole metabolic fuel for ATP production by human cells. In the present work, we investigated the possible origins of the occurrence of this misconception among students. The analysis of students' answers to questionnaires indicated that the misconception appears as soon as in the 8th grade and remains unchanged throughout subsequent school years. The analysis of grade textbooks showed that the misconception is likely to be a consequence of the teaching of nutrition in the 8th grade, when a single function is emphasized for each nutrient. The energetic function is mainly associated with carbohydrates, while proteins and lipids are considered structural and storage molecules, respectively. An extreme similarity was observed between students' knowledge of nutrient's function and textbook contents. Analysis of high‐school textbooks suggested that the misconception would be reinforced because of the detailed teaching only of glucose metabolism, with rare mention of lipids or amino acids as metabolic fuels. The consequences of that approach are discussed and suggestions are made on an alternative teaching of energy‐yielding metabolism.
The accuracy of risk assessment instruments in the prediction of impulsive versus predatory aggression
Authors: McDermott Barbara E. , Quanbeck Cameron D. , Busse David , Yastro Kalynn , Scott Charles L. 
Published: November 2008

AbstractActuarial violence risk assessments, many of which include the construct of psychopathy, have been shown to be superior to clinical judgment in the prediction of long‐term risk of community violence and recidivism. While these instruments initially appeared to provide similarly accurate judgments of risk of institutional aggression, recent research has indicated that such assessments may be less robust in this setting. One explanation may lie in the types of aggression most frequently observed in each setting. Impulsive (or reactive/affective) is the type of physical aggression most commonly exhibited in psychiatric facilities. This research examines the relationship between risk assessments and aggression in an inpatient forensic setting, with such aggression categorized as impulsive, predatory or psychotic aggression. Consistent with previous research, impulsive aggression was the most frequent type observed (58%). Anger (as measured by the Novaco Anger Scale) and clinical issues (as measured by the HCR‐20) were most associated with impulsive aggression, with AUC values of .73 and .71 respectively. In contrast, anger and psychopathy (as measured by the PCL‐R) were more associated with predatory aggression, with AUC values of .95 and .84 respectively. Psychotic symptoms were highly associated with psychotically motivated aggression (AUC = .90). These results suggest that traditional violence risk assessments may have limited utility in predicting aggression in an institutional setting and that psychiatric symptoms and heightened affect are more relevant. Copyright © 2008 John Wiley & Sons, Ltd.
Oligosubstituted Pyrroles Directly from Substituted Methyl Isocyanides and Acetylenes
Authors: Lygin Alexander V. , Larionov Oleg V. , Korotkov Vadim S. , de Meijere Armin 
Published: November 2008

AbstractThe formal cycloaddition of α‐metallated methyl isocyanides 1 onto the triple bond of electron‐deficient acetylenes 2 represents a direct and convenient approach to oligosubstituted pyrroles 3. The scope and limitations of this reaction (24 examples, 25–97 % yield) are reported along with an optimization of the reaction conditions and a rationalization of the mechanism. In addition, a related newly developed CuI‐mediated synthesis of 2,3‐disubstituted pyrroles by the reaction of copper acetylides derived from unactivated terminal alkynes with substituted methyl isocyanides is described (11 examples, 5–88 %yield).
DCDHF Fluorophores for Single‐Molecule Imaging in Cells
Authors: Lord Samuel J. , Conley Nicholas R. , Lee Hsiao‐lu D. , Nishimura Stefanie Y. , Pomerantz Andrea K. , Willets Katherine A. , Lu Zhikuan , Wang Hui , Liu Na , Samuel Reichel , Weber Ryan , Semyonov Alexander , He Meng , Twieg Robert J. , Moerner W. E. 
Published: November 2008

AbstractThere is a persistent need for small‐molecule fluorescent labels optimized for single‐molecule imaging in the cellular environment. Application of these labels comes with a set of strict requirements: strong absorption, efficient and stable emission, water solubility and membrane permeability, low background emission, and red‐shifted absorption to avoid cell autofluorescence. We have designed and characterized several fluorophores, termed “DCDHF” fluorophores, for use in live‐cell imaging based on the push–pull design: an amine donor group and a 2‐dicyanomethylene‐3‐cyano‐2,5‐dihydrofuran (DCDHF) acceptor group, separated by a π‐rich conjugated network. In general, the DCDHF fluorophores are comparatively photostable, sensitive to local environment, and their chemistries and photophysics are tunable to optimize absorption wavelength, membrane affinity, and solubility. Especially valuable are fluorophores with sophisticated photophysics for applications requiring additional facets of control, such as photoactivation. For example, we have reengineered a red‐emitting DCDHF fluorophore so that it is dark until photoactivated with a short burst of low‐intensity violet light. This molecule and its relatives provide a new class of bright photoactivatable small‐molecule fluorophores, which are needed for super‐resolution imaging schemes that require active control (here turning‐on) of single‐molecule emission.
Sequence‐Specific Positions of Water Molecules at the Interface between DNA and Minor Groove Binders
Authors: Spitzer Gudrun M. , Fuchs Julian E. , Markt Patrick , Kirchmair Johannes , Wellenzohn Bernd , Langer Thierry , Liedl Klaus R. 
Published: November 2008

AbstractLigands able to specifically recognize DNA sequences are of fundamental interest as transcription‐controlling drugs. Herein, we analyze the positions of water molecules relative to B‐DNA base pairs in the minor groove of X‐ray and NMR protein data bank (PDB) structures. The patterns observed for water molecules at the interface between DNA and a ligand are compared with those obtained for structures without a ligand. Although the ligand end groups are often charged, and therefore highly hydrated, they do not alter the water patterns, which show considerable differences for the AT and CG base pairs. For AT they are much more precise than for CG in both ligand‐containing and ligand‐free structures. This behavior strongly indicates that the release of water molecules upon ligand binding leads to a gain of entropy and explains why this effect is especially pronounced for A‐tract B‐DNA sequences.
A flexible multicarrier CDMA system with time‐varying data rates and services
Authors: You Cheolwoo , Chung Wonzoo , Jeon Taehyun 
Published: November 2008

AbstractWe consider an enhanced multicarrier code‐division multiple access (CDMA) system that performs the spreading in the time and frequency domains simultaneously, where time‐domain spreading codes are used as a main code and frequency‐domain spreading codes (FDSCs) are used as a subcode. By allocating the FDSCs to users, rates and services can be dynamically matched to users' needs. The resulting system can support different time‐varying source rates and, therefore, enable multimedia applications. In addition, since the proposed scheme uses multiple carriers, it has some advantages such as the mitigated multipath fading, frequency/path diversity and narrowband interference suppression capability, in contrast to a single carrier (SC) system such as the multicode CDMA scheme. Finally, the closed‐form expression for probability of bit error is derived for a frequency‐selective Rayleigh fading channel. It has been also shown that the proposed system has outperformed the conventional SC RAKE system if the available bandwidth is fixed. Copyright © 2008 John Wiley & Sons, Ltd.
Cre‐mediated recombination in pituitary somatotropes
Authors: Nasonkin Igor O. , Potok Mary Anne , Camper Sally A. 
Published: November 2008

AbstractWe report a transgenic line with highly penetrant cre recombinase activity in the somatotrope cells of the anterior pituitary gland. Expression of the cre transgene is under the control of the locus control region of the human growth hormone gene cluster and the rat growth hormone promoter. Cre recombinase activity was assessed with two different lacZ reporter genes that require excision of a floxed stop sequence for expression: a chick β‐actin promoter with the CMV enhancer transgene and a ROSA26 knock‐in. Cre activity is detectable in the developing pituitary after initiation of Gh transcription and persists through adulthood with high penetrance in Gh expressing cells and lower penetrance in lactotropes, a cell type that shares a common origin with somatotropes. This Gh‐cre transgenic line is suitable for efficient, cell‐specific deletion of floxed regions of genomic DNA in differentiated somatotropes and a subset of lactotrope cells of the anterior pituitary gland. genesis 47:55–60, 2009. © 2008 Wiley‐Liss, Inc.
Building Higher Carbohydrates via Dioxanone Aldol Chemistry: The α,α′‐Bisaldol Approach
Authors: Niewczas Izabella , Majewski Marek 
Published: November 2008

AbstractA synthetic approach to higher carbohydrates via the sequence of two aldol reactions that proceed at the α and α′ positions of 2,2‐dimethyl‐1,3‐dioxan‐5‐one (dioxanone) is described. As reported before, the first aldol reaction works well under organocatalytic conditions (proline catalysis), this is followed by protection of the hydroxy, deprotonation of the resulting compound using excess of LDA, and the second aldol addition. This sequence of reactions gives compounds having a straight‐chain carbon skeleton with an oxygen‐based functional group at each carbon. Most of the groups are protected. The utility of this strategy is illustrated by short syntheses of 6‐C‐phenyl‐D‐glycero‐D‐allo‐hexopyranose and D‐erythro‐D‐allooctopyranose(© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2009)
Flux‐difference splitting‐based upwind compact schemes for the incompressible Navier–Stokes equations
Authors: Shah Abdullah , Yuan Li 
Published: November 2008

AbstractThird‐order and fifth‐order upwind compact finite difference schemes based on flux‐difference splitting are proposed for solving the incompressible Navier–Stokes equations in conjunction with the artificial compressibility (AC) method. Since the governing equations in the AC method are hyperbolic, flux‐difference splitting (FDS) originally developed for the compressible Euler equations can be used. In the present upwind compact schemes, the split derivatives for the convective terms at grid points are linked to the differences of split fluxes between neighboring grid points, and these differences are computed by using FDS. The viscous terms are approximated with a sixth‐order central compact scheme. Comparisons with 2D benchmark solutions demonstrate that the present compact schemes are simple, efficient, and high‐order accurate. Copyright © 2008 John Wiley & Sons, Ltd.
Numerical studies of blood flow in healthy, stenosed, and stented carotid arteries
Authors: Gay Mickaël , Zhang Lucy T. 
Published: November 2008

AbstractNumerical analysis of pulsatile blood flow in healthy, stenosed, and stented carotid arteries is performed with the aim of identifying hemodynamic factors in the initiation, growth, and the potential of leading to severe occlusions of a diseased artery. The Immersed Finite Element Method is adopted for this study to conveniently incorporate various geometrical shapes of arteries without remeshing. Our computational results provide detailed quantitative analysis on the blood flow pattern, wall shear stress, particle residence time, and oscillatory shear index. The analysis of these parameters leads to a better understanding of blood clot formation and its localization in a stenosed and a stented carotid artery. A healthy artery is also studied to establish a baseline comparison. This analysis will assist in developing treatments for diseased arteries and novel stent designs to reduce restenosis. Copyright © 2008 John Wiley & Sons, Ltd.
Gene position within chromosome territories correlates with their involvement in distinct rearrangement types in thyroid cancer cells
Authors: Gandhi Manoj S. , Stringer James R. , Nikiforova Marina N. , Medvedovic Mario , Nikiforov Yuri E. 
Published: November 2008

AbstractChromosomal rearrangements in human cancers are of two types, interchromosomal, which are rearrangements that involve exchange between loci located on different chromosomes, and intrachromosomal, which are rearrangements that involve loci located on the same chromosome. The type of rearrangement that typically activates a specific oncogene may be influenced by its nuclear location and that of its partner. In interphase nuclei, each chromosome occupies a distinct three‐dimensional (3D) territory that tends to not overlap the territories of other chromosomes. It is also known that after double strand breaks in the genome, mobility of free DNA ends is limited. These considerations suggest that loci located deep within a chromosomal territory might not participate in interchromosomal rearrangements as readily as in intrachromosomal rearrangements. To test this hypothesis, we used fluorescence in situ hybridization with 3D high‐resolution confocal microscopy to analyze the positions of six oncogenes known to be activated by recombination in human cancer cells. We found that loci involved in interchromosomal rearrangements were located closer to the periphery of chromosome territories as compared with the loci that were involved in intrachromosomal inversions. The results of this study provide evidence suggesting that nuclear architecture and location of specific genetic loci within chromosome territories may influence their participation in intrachromosomal or interchromosomal rearrangements in human thyroid cells. © 2008 Wiley‐Liss, Inc.