bluuebunny/crossref_metadata_2025_split huggingface dataset:
Eco-Friendly Simultaneous Estimation of Ponceau 4R and Carmoisine Employing an Analytical Quality by Design-Aided RP-HPLC Method in Commercial Food Samples Utilizing a Green Ultrasound-Assisted Extraction Technique
Authors: Chakraborty Atyurmila , Jayaseelan Kavitha 
Published: March 2024

Abstract

Background
Ponceau 4R (E124) and carmoisine (CMS; E122) are frequently utilized azo synthetic dyes in the food industry owing to their aesthetically pleasing coloration and broad consumer acceptability. It is imperative to prioritize environmentally favorable technologies for quantifying these dyes, as excessive consumption of these poses significant health risks.

Objective
The primary objective of this research was to establish a reversed-phase (RP)-HPLC method that could simultaneously detect Ponceau 4R and CMS, implementing green analytical chemistry (GAC) and analytical quality by design (AQbD), using an ultrasound-assisted extraction (UAE) technique in commercial food samples.

Methods
An Agilent Eclipse Plus column (C18, 250 × 4.6 mm id, 5 µm) was utilized for effective separation with a mobile phase of ethanol-acetate buffer pH 5 (60:40, v/v), flow rate of 1 mL/min, and detection wavelength of 515 nm. Critical variables selected for method optimization were ethanol percentage and flow rate, determined using central composite design (CCD). In order to adhere to the 12 principles of green chemistry, hazardous solvents were substituted with ethanol, which is distinguished by its ease of use, effectiveness, and ecological sustainability. The greenness assessment was conducted utilizing the green analytical procedure index (GAPI), analytical eco-scale (AES), and analytical greenness metrics (AGREE).

Results
The respective retention times for Ponceau 4R and CMS were 2.276 and 3.450 min. The recovery rate of Ponceau 4R and CMS fluctuated between 70% and 102% and 80% and 102%, respectively, across various marketed food samples. The procedure passed validation in accordance with the International Conference on Harmonization Q14 guidelines.

Conclusion
The devised method demonstrates that the validation parameters like linearity, precision, sensitivity, and reproducibility are within the specified limits of ICH guidelines. The greenness assesment tools GAPI, AES, and AGREE produced the most favorable results.

Highlights
In future, environmentally sustainable, solvent-based, robust AQbD methodologies for assessing varieties of food colorants may be adopted and improved commercially.
Midrange, Differential, Meaningful, and Multidisciplinary: Reflections onJCR’s Epistemic Culture
Authors: Giesler Markus 
Published: March 2024

AbstractScientific communities such as journals or professional societies have their own ways of creating and sharing knowledge called “epistemic cultures.” Drawing on prior reflexive scholarship and conversations with eight preeminent consumer researchers, this article explores some of the central tenets of epistemic culture at the Journal of Consumer Research (JCR): midrange scope, differential insight, meaningful impact, and multidisciplinary field. It also provides some guidance to new consumer researchers on how to accomplish epistemic fluency.
RETRACTED AND REPLACED: Mitochondrial background can explain variable costs of immune deployment
Authors: Kutzer Megan A M , Cornish Beth , Jamieson Michael , Zawistowska Olga , Monteith Katy M , Vale Pedro F 
Published: March 2024

Abstract
Organismal health and survival depend on the ability to mount an effective immune response against infection. Yet immune defence may be energy-demanding, resulting in fitness costs if investment in immune function deprives other physiological processes of resources. While evidence of costly immunity resulting in reduced longevity and reproduction is common, the role of energy-producing mitochondria on the magnitude of these costs is unknown. Here we employed Drosophila melanogaster cybrid lines, where several mitochondrial genotypes (mitotypes) were introgressed onto a single nuclear genetic background, to explicitly test the role of mitochondrial variation on the costs of immune stimulation. We exposed female flies carrying one of nine distinct mitotypes to either a benign, heat-killed bacterial pathogen (stimulating immune deployment while avoiding pathology) or a sterile control and measured lifespan, fecundity, and locomotor activity. We observed mitotype-specific costs of immune stimulation and identified a positive genetic correlation between life span and the proportion of time cybrids spent moving while alive. Our results suggest that costs of immunity are highly variable depending on the mitochondrial genome, adding to a growing body of work highlighting the important role of mitochondrial variation in host–pathogen interactions.
Vanderstock v Victoria: Fiscal Federalism Meets Environmental Constitutionalism?
Authors: Weis Lael K 
Published: March 2024

Abstract
This analysis critically examines the High Court of Australia’s recent decision in Vanderstock & Anor v The State of Victoria [2023] HCA 30 as an instance of environmental impact litigation (‘EIL’). The Vanderstock plaintiffs successfully challenged a state tax on low-emissions and electric vehicles on the basis that it was a duty of excise: a tax that can only be imposed by the federal parliament under s 90 of the Australian Constitution. However, the analysis cautions against viewing the decision as a victory for the environment. The High Court’s ruling has significant consequences for federal fiscal relations. At best, these have ambivalent implications for environmental policy. At worst, they may hamper or defeat environmental policy initiatives. Vanderstock thus offers a cautionary lesson for constitutional EIL, suggesting that any evaluation of the ‘impact’ of such litigation must have regard for structural implications of the legal norms involved.
Spontaneous hemorrhagic thyroid nodule: a case report and review of the literature
Authors: Alsalamah Shmokh , Albesher Meshal , Alwabili Mohammed , Almutairy Alyaa 
Published: March 2024

Abstract
Spontaneous hemorrhage within thyroid nodules is infrequent and challenging to manage. Patients with this condition typically manifest acute neck pain, swelling, and discomfort. This report details a rare case of a 49-year-old male patient who was not known to have any history of thyroid disease. He presented with a distinctive clinical scenario of a spontaneous hemorrhagic thyroid nodule that was managed surgically and had a satisfying outcome. In addition, we have conducted a review of the literature regarding the clinical presentation, diagnosis, and outcomes of published cases in correlation with our discussed case.
Band-like transport in solution-processed perylene diimide dianion films with high Hall mobility
Authors: Jia Yanhua , Jiang Qinglin , Gan Hanlin , Wang Bohan , He Xiandong , Zhou Jiadong , Ma Zetong , Zhang Jiang , Ma Yuguang 
Published: March 2024

ABSTRACT
It is crucial to prepare high-mobility organic polycrystalline film through solution processing. However, the delocalized carrier transport of polycrystalline films in organic semiconductors has rarely been investigated through Hall-effect measurement. This study presents a strategy for building strong intermolecular interactions to fabricate solution-crystallized p-type perylene diimide (PDI) dianion films with a closer intermolecular π–π stacking distance of 3.25 Å. The highly delocalized carriers enable a competitive Hall mobility of 3 cm2 V−1 s−1, comparable to that of the reported high-mobility organic single crystals. The PDI dianion films exhibit a high electrical conductivity of 17 S cm−1 and typical band-like transport, as evidenced by the negative temperature linear coefficient of mobility proportional to T−3/2. This work demonstrates that, as the intermolecular π–π interactions become strong enough, they will display high mobility and conductivity, providing a new approach to developing high-mobility organic semiconductor materials.
A heat transfer model for liquid film boiling on micro-structured surfaces
Authors: Li Pengkun , Zou Qifan , Liu Xiuliang , Yang Ronggui 
Published: March 2024

ABSTRACT
High heat transfer coefficient (HTC) and critical heat flux (CHF) are achieved in liquid film boiling by coupling vibrant vapor bubbles with a capillary liquid film, which has thus received increased interest for thermal management of high-power electronics. Although some experimental progress has been made, a high-fidelity heat transfer model for liquid film boiling is lacking. This work develops a thermal-hydrodynamic model by considering both evaporation atop the wick and nucleate boiling inside the wick to simultaneously predict the HTC and CHF. Nucleate boiling is modeled with microlayer evaporation theory, where a unified scaling factor is defined to characterize the change of microlayer area with heat flux. The scaling factor η is found to be independent of wicking structure and can be determined from a few measurements. This makes our model universal to predict the liquid film boiling heat transfer for various micro-structured surfaces including micropillar, micropowder, and micromesh. This work not only sheds light on understanding fundamental mechanisms of phase-change heat transfer, but also provides a tool for designing micro-structured surfaces in thermal management.
Evaluating Clinical Sequelae of the Carbapenem-Valproate Interaction: A Retrospective Analysis
Authors: Petrucelli Nick , Hayes Bryan D , Shelat Nidhi , Elshaboury Ramy H , Pearson Jeffrey C , Koehl Jennifer L 
Published: March 2024

Abstract

Background
Previous studies identified a rapid decrease in valproate serum concentrations when coadministered with a carbapenem; however, the specific consequences and subsequent therapy adjustments are not well described. We aimed to investigate the clinical and therapeutic implications of the carbapenem-valproate drug-drug interaction.

Methods
This retrospective analysis included data from 2 large academic medical centers during January 2017 to June 2022. The primary outcome was incidence of seizures or behavioral events stratified by valproate indication. All adult patient encounters with concomitant administration of any carbapenem antimicrobial and valproate were included. Patients without prolonged exposure to valproate prior to hospitalization, without valproate levels pre– and post–carbapenem administration, with an admitting diagnosis of seizure, with exposure to other agents that decrease valproate concentrations, or who had a seizure during the hospitalization prior to carbapenem exposure were excluded.

Results
Two hundred fifty-eight episodes of concomitant use among 78 unique adult patients were included. Valproate was used for seizure control in 41 patients (52.6%) and for mood-related disorders in 37 (47.4%). In those prescribed valproate for its antiepileptic properties, seizures occurred following carbapenem administration in 46.3% of encounters. In those taking valproate for mood-related disorders, 50.8% met the primary endpoint of behavioral disturbance.

Conclusions
Our study demonstrates significant clinical implications of the carbapenem-valproate interaction. Clinicians should be aware of this interaction and consider alternative antimicrobial and/or antiepileptic agents whenever possible. Adding or increasing doses of antiepileptic agents and/or consultation with a neurologist prior to concomitant use should be considered when this combination cannot be avoided.
Chasing the Total Solar Eclipse
Authors: Lange Henrike Christiane , McLeish Tom 
Published: March 2024

Abstract
In the Introduction, Lange and McLeish combine a field report from McLeish’s travel diary to the total solar eclipse of 2017 in Crofton, Kentucky with their reflection on scholarly, historical, and archival work. The Introduction explores why the theme of the total solar eclipse opens an ideal gateway into a vivid conversation between multiple interdisciplinary perspectives. A discussion of the history of science and the ‘two cultures’ leads into the presentation of the book as a model and framework for interdisciplinary work across all borders between the sciences, arts, humanities, history, theology, as well as between lay and expert audiences. An overview of existing eclipse literature and differentiation is followed by a closing reflection on how this unique volume enables readers to approach the experience of a total solar eclipse themselves while simultaneously inviting them into all the many disciplines represented within the specialist authors’ fields, scientific methods, and scholarly approaches.
From Science to Story
Authors: Frost Mike 
Published: March 2024

Abstract
The previous chapters have shown that total solar eclipses feature dramatic and unique phenomena, resulting in a spectacle worth seeing at least once in one’s lifetime. Indeed, there are some astronomers—actually, a whole community of eclipse–chasers—who travel the world to see eclipse after eclipse. Why is one eclipse not enough, and why do some people devote so much time, effort, and money to eclipse–chasing? Let’s meet one of them. The author is an astronomer and astronomical historian, who relishes traveling the world to see solar eclipses, and enjoys being part of the community of umbraphiles—those who love being in the moon’s shadow.
‘The Face of the World was Wretched, Horrifying, Black, Remarkable’
Authors: Gasper Giles 
Published: March 2024

Abstract
We are now moving on from early Asia to medieval Scandinavia and Europe — from China, India, and Babylonia to Norway, Ireland, and England. The cultural focus will be placed on sources from the Christian tradition moving over a wide geographical range from the lands of the medieval Rus’ to the Atlantic archipelago in the west, crossing linguistic, political, and religious boundaries. Christian scholars, scientists, and theologians in the European Middle Ages developed their own responses to the science, experience, and interpretation of total solar eclipses. Many medieval thinkers also held a religious office and tried to reconcile their vision and knowledge of the material world with their beliefs as well as with their theological knowledge from scripture. The description of the 1133 total solar eclipse as simultaneously ‘Wretched, Horrifying, Black, Remarkable’ goes hand in hand with the wider contemporary efforts of bridging of empirical and interpretative astronomical approaches in the Christian twelfth century.
Eclipsed?
Authors: Olson Roberta J. M. 
Published: March 2024

Abstract
From the fourteenth-century literary tradition around Dante, Chapter 10 leaps forward to the eighteenth and nineteenth centuries—a new era, grounded in the Copernican revolution with the Sun at the centre of the solar system, which impacted the visualization of total solar eclipses and connects to momentous revolutions in science, technology, and journalism before and after the beginning of photography. Until recently, artistic representations of total solar eclipses have not been examined in depth within their scientific and cultural context. The author’s articles on the subject, her collaborations with astronomer Jay M. Pasachoff beginning in 1992, and her book Cosmos with Pasachoff (2019) have been among the first serious considerations. The following chapter contains new material on the rich context of Western nineteenth-century art history on total solar eclipses.
When Words Fail
Authors: Hild Elaine Stratton 
Published: March 2024

Abstract
We complete our selective survey of eclipses across the arts by listening for the seemingly impossible—for how could a phenomenon as utterly soundless as an eclipse generate responses in the inherently aural form of music? This genre-crossing chapter will lead from Handel to Pink Floyd through a broad variety of eclipse engagement in the history of Western music, from the classical style to Sir John Kenneth Tavener, to pop and rap music, including the famous eclipse tunes by Welsh popstar Bonnie Tyler and ecliptic imagery in the tunes of the American rapper YoungBoy Never Broke Again (Kentrell deSean Gaulden). The interaction of thematic questions and case studies invites readers/listeners to consider music in all dimensions—remembering that music has also the capacity of expressing the wordless and transcendent features of the total solar eclipse experience, the musical chasing of total solar eclipses becomes a more immanent endeavour.
Animal Behaviour and Eclipse
Authors: Portugal Steven J. 
Published: March 2024

Abstract
Humans are not the only species trying to make sense of eclipses. Though animals have not developed the same cultural–artistic responses to the stunning cosmic event, many of them show a fine-tuned sensitivity to the sudden and unusual change in the Sun. Indeed, their circadian rhythm, migration patterns, and mating behaviours are set to the regularity of sunlight, twilight, day, and night in their predictable seasonal and diurnal patterns. Animals’ behavioural reactions to eclipses have attracted great interest – surely in part because they confirm something about total solar eclipses that runs deeper than the human mind’s painstaking calculations, representations, and interpretations. The field of animal behaviour studies is rapidly changing with the exponential growth of progress in digital technology, especially when it comes to tracking devices that, only in recent years, have opened an entirely new spectrum of knowledge about individual animals’ responses to total solar eclipses: they help create an outdoor lab that did not exist before. Looking for an imaginative understanding of the vast ranges of animal experiences of the total solar eclipse, the following chapter takes us into various ecospheres and to many creatures around the world— from fireflies and spiders to elephants, from indigo buntings to zooplankton. The richly illustrated chapter is also a reminder of the variety of species around the world, their specificity, and the all-encompassing reach of the total solar eclipse as a phenomenon that touches all of them.
Conclusion
Authors: Lange Henrike Christiane , McLeish Tom 
Published: March 2024

Abstract
In their conclusion to this volume, Lange and McLeish look from the experience of the extraordinary cosmic event of the total solar eclipse back to everyday observations of the cosmos. They revisit the value of the work of the eye and the mind as represented in the chapters of this book, finding that awareness, attention, and awe set the standard for living a scientific–humanistic–artistic practice of attention and focus, of perception and processing, of excitement and enthusiasm, of curiosity and questioning, and last but never least, of sharing knowledge in mutual appreciation of diverse fields. Rather than thinking of interdisciplinarity as a superstructure over disparate islands of knowledge, Lange and McLeish propose the idea of a deep dive into the common core of all academic, scientific, and artistic practices. The authors draw on examples from poetry (Sappho, Claudius, Calvino) to emphasize that the challenge of interdisciplinarity as engaging with the cosmos is as much poetic as it is scientific. Methodologically they come to the conclusion that one major principle for a successful interdisciplinary collaborative practice within or beyond the walls of academia appears to be one’s thorough understanding of at least one discipline in depth engaged with others in mutual appreciation, curiosity, discovery, and undaunted awe.
Association of diverticulitis and potential risk of ischemic stroke: population-based matched cohort study in Taiwan
Authors: Chen Kuan , Wang Yung-Chang , Yang Kuang-Tsu , Huang Ting-Hsin , Hung Yao-Min , Chang Renin 
Published: March 2024

Abstract

Background
Previous studies have suggested relationship between diverticular disease and cardiovascular disease. Since cardiovascular disease and cerebrovascular accident share a lot of pathogenesis, diverticulitis could also be a risk factor for stroke. This study tried to establish epidemiological evidence of the relationship between colon diverticulitis and ischemic stroke.

Methods
In this retrospective cohort study, patients with newly diagnosed colon diverticulitis (N = 6238) and patients without colon diverticulitis (control group; N = 24 952) were recruited between January 1, 2000, and December 31, 2017. Both groups were matched by propensity score at a 1:4 ratio by age, sex, comorbidities and medications. Cox proportional hazard regression was applied to estimate the hazard ratio (HR) and 95% confidence interval (CI) of ischemic stroke. We also conducted 4 different regression models and 2 sensitivity analyses to test the robustness of our findings.

Results
The diverticulitis group had a higher risk of IS than the control group (adjusted HR, 1.25; 95% CI, 1.12–1.39; P &lt; 0.001). Serial sensitivity analyses yielded consistent positive link between diverticulitis and IS. Further subgroup analysis showed that in the study group, the risk of IS was 2.54-fold higher than the matched controls in 30–39 years.

Conclusions
Our study found that colon diverticulitis was associated with a higher risk of developing subsequent ischemic stroke, especially for patients aged 30–39 years, among Asian population. This result provides us a chance to undertake preventive measures for ischemic stroke in high-risk patients.
Precipitation causes quality losses of large economic relevance in wheat production
Authors: Bucheli Janic , Visse-Mansiaux Margot , Herrera Juan , Häner Lilia Levy , Tack Jesse , Finger Robert 
Published: March 2024

Abstract
Adverse weather conditions can affect both crop yield quantity and yield quality. In wheat production, especially the risk of a downgrading due to low baking quality, as indicated by the Hagberg Falling Number, can cause large economic losses after precipitation events. We here estimate precipitation effects on the risk of such a downgrading and quantify the resulting economic losses. To this end, we leverage a panel dataset from the Swiss wheat varieties trial network (N = 1,859) and high-quality weather data. We use a fixed effects estimation framework to estimate precipitation effects and simulate economic losses. We find that precipitation close to harvest significantly increases the risk of a downgrading due to low baking quality. Moreover, downgrading events cause large revenue reductions of up to 1,445 Swiss francs per hectare. This adds new economic insights, highlights the role of weather-dependent crop quality, and provides a basis to improve risk management.