bluuebunny/crossref_metadata_2025_split huggingface dataset:
Temperamental underpinnings of borderline personality disorder and its facets
Authors: Brud Piotr P. , Cieciuch Jan 
Published: March 2024

AbstractTemperament is claimed to be the basis for personality; therefore, discovering the temperamental underpinnings of borderline personality disorder and its facets is crucial for understanding this personality disorder. In this article, we explore these underpinnings by using a new model of temperament, based on the Regulative Theory of Temperament, the Big Two of temperament, and the Circumplex of Personality Metatraits. Two studies were conducted on adults—the first was in a general population sample (N = 315) and the second was in a clinical sample (N = 113) in people with a diagnosis of borderline personality disorder. The following measurements were used: The Screening Instrument for Borderline Personality Disorder (SI‐Bord), the Five‐Factor Borderline Inventory‐Short Form (FFBI‐SF), and the Temperament Metadimensions Questionnaire (TMQ). General borderline was explained by Reactivity (high Sensitivity) and Activity (high Dynamism). At the facet level, the Borderline Internalizing Facet was mainly explained by Reactivity (high Sensitivity), while the Borderline Externalizing Facet was explained by Activity (high Dynamism) in addition to Reactivity (high Sensitivity). The results of our study revealed specific temperamental underpinnings of borderline and its facets. Reactivity underlies all borderline facets, while Activity differentiates between the Borderline Externalizing Facet and Borderline Internalizing Facet.
Identification of gravity‐responsive serum proteins in spaceflight mice using a quantitative proteomic approach with data‐independent acquisition mass spectrometry
Authors: Kimura Yayoi , Nakai Yusuke , Ino Yoko , Akiyama Tomoko , Moriyama Kayano , Ohira Takashi , Saito Tomoyuki , Inaba Yutaka , Kumagai Ken , Ryo Akihide , Hirano Hisashi 
Published: March 2024

AbstractPhysical inactivity associated with gravity unloading, such as microgravity during spaceflight and hindlimb unloading (HU), can cause various physiological changes. In this study, we attempted to identify serum proteins whose levels fluctuated in response to gravity unloading. First, we quantitatively assessed changes in the serum proteome profiles of spaceflight mice using mass spectrometry with data‐independent acquisition. The serum levels of several proteins involved in the responses to estrogen and glucocorticoid, blood vessel maturation, osteoblast differentiation, and ossification were changed by microgravity exposure. Furthermore, a collective evaluation of serum proteomic data from spaceflight and HU mice identified 30 serum proteins, including Mmp2, Igfbp2, Tnc, Cdh5, and Pmel, whose levels varied to a similar extent in both gravity unloading models. These changes in serum levels could be involved in the physiological changes induced by gravity unloading. A collective evaluation of serum, femur, and soleus muscle proteome data of spaceflight mice also showed 24 serum proteins, including Igfbp5, Igfbp3, and Postn, whose levels could be associated with biological changes induced by microgravity. This study examined serum proteome profiles in response to gravity unloading, and may help deepen our understanding of microgravity adaptation mechanisms during prolonged spaceflight missions.
Tire tread rubber compound with high wet skid resistance and low rolling resistance
Authors: Hou Xiaogeng , Hou Hongbin , Wang Yixiao , Qin Bao , Zhang Liang , Wang Qinggang 
Published: March 2024

AbstractThe preparation of four types of epoxidized iron‐based comb butadiene‐isoprene rubber (EBIR) with different epoxidation degrees (4.7%, 6.4%, 10.2%, and 12.3%) was investigated for the first time in this study. The modification involved the use of hydrogen peroxide and formic acid as raw materials for the epoxidation process. Following this, silica/EBIR composites were prepared by mixing EBIR with silica nanoparticles, without the use of a silane coupling agent (SCA). The objective was to investigate the influence of the epoxidation degree on the structure and properties of the resulting silica/EBIR nanocomposites. The results indicated that the introduction of epoxy groups had a positive effect on the interfacial interaction between the rubber and filler, leading to improved dispersion of the silica nanoparticles in the rubber matrix. Consequently, the tensile properties, wet skid resistance, and abrasion resistance of the silica/EBIR composites were found to be superior to those of the un‐epoxidized silica/BIR composites. Furthermore, comparing the silica/EBIR‐12.3 nanocomposites with silica/BIR‐Si69 nanocomposites, it was revealed that silica/EBIR‐12.3 showed a 69.4% enhancement in wet skid resistance and an 8.0% reduction in rolling resistance. These findings demonstrate the potential of silica/EBIR composites for high‐performance tire tread rubber applications, offering environmental benefits and improved properties.
Respiratory morbidity among offspring misclassified as growth restricted
Authors: Zamstein Omri , Wainstock Tamar , Sheiner Eyal 
Published: March 2024

AbstractObjectiveAn ultrasound‐based diagnosis implies that some fetuses suspected to be growth‐restricted (FGR) are discovered at birth to be appropriately grown (appropriate for gestational age [AGA] birth weight, between the 10th and 90th percentile). These fetuses may thus be exposed to unnecessary medical interventions, including early labor induction. In this study, we have evaluated the long‐term respiratory health of offspring misclassified as FGR.Study DesignA population‐based cohort analysis was conducted, including deliveries of AGA singletons between 1991 and 2021 at a tertiary referral hospital. Incidence of morbidity due to various respiratory conditions was compared between AGA offspring with prenatal diagnosis of FGR, and those without a false diagnosis of FGR. The Kaplan–Meier approach was used to estimate cumulative morbidity incidence. The stratified Cox proportional‐hazards model was used to control for confounders.ResultsA total of 324,620 deliveries of AGA newborns were included in the analyses; 3249 of them (1.0%) were misclassified prenatally as FGR. The FGR subgroup delivered at an earlier gestational age (36.7 vs. 39.1 weeks, p < .001) and had more than 25% higher incidence of respiratory‐related morbidity during childhood (33.2% vs. 26.5%), specifically related to asthma and obstructive sleep apnea (p < .001 for all). A higher cumulative morbidity rate due to respiratory conditions was observed in the Kaplan–Meier survival curve (log‐rank p value < .001). This association between FGR and respiratory morbidity was independent of preterm delivery, maternal age, cesarean delivery, and child's birth year (adjusted hazard ratio = 1.14, 95% confidence interval: 1.07–1.21, p < .001), using a Cox proportional hazards model.ConclusionAGA newborns misclassified as FGR, are at an increased risk for long‐term respiratory morbidity during childhood and adolescence.
A west African ancestry‐associated SNP on 8q24 predicts a positive biopsy in African American men with suspected prostate cancer following PSA screening
Authors: Gu Jian , Chery Lisly , González Graciela M. Nogueras , Huff Chad , Strom Sara , Jones Jeffrey A. , Griffith Donald P. , Canfield Steven E. , Wang Xuemei , Huang Xuelin , Roberson Pamela , Meng Qing H. , Troncoso Patricia , Ittmann Michael , Covinsky Michael , Scheurer Michael , Irizarry Ramirez Margarita , Pettaway Curtis A. 
Published: March 2024

AbstractBackgroundAfrican American (AA) men have the highest incidence and mortality rates of prostate cancer (PCa) among all racial groups in the United States. While race is a social construct, for AA men, this overlaps with west African ancestry. Many of the PCa susceptibility variants exhibit distinct allele frequencies and risk estimates across different races and contribute substantially to the large disparities of PCa incidence among races. We previously reported that a single‐nucleotide polymorphism (SNP) in 8q24, rs7824364, was strongly associated with west African ancestry and increased risks of PCa in both AA and Puerto Rican men. In this study, we determined whether this SNP can predict biopsy positivity and detection of clinically significant disease (Gleason score [GS] ≥ 7) in a cohort of AA men with suspected PCa.MethodsSNP rs7824364 was genotyped in 199 AA men with elevated total prostate‐specific antigen (PSA) (>2.5 ng/mL) or abnormal digital rectal exam (DRE) and the associations of different genotypes with biopsy positivity and clinically significant disease were analyzed.ResultsThe variant allele carriers were significantly over‐represented in the biopsy‐positive group compared to the biopsy‐negative group (44% vs. 25.7%, p = 0.011). In the multivariate logistic regression analyses, variant allele carriers were at a more than a twofold increased risk of a positive biopsy (odds ratio [OR] = 2.14, 95% confidence interval [CI] = 1.06–4.32). Moreover, the variant allele was a predictor (OR = 2.26, 95% CI = 1.06–4.84) of a positive biopsy in the subgroup of patients with PSA < 10 ng/mL and normal DRE. The variant allele carriers were also more prevalent in cases with GS ≥ 7 compared to cases with GS < 7 and benign biopsy.ConclusionsThis study demonstrated that the west African ancestry‐specific SNP rs7824364 on 8q24 independently predicted a positive prostate biopsy in AA men who were candidates for prostate biopsy subsequent to PCa screening.
Atezolizumab‐related sclerosing cholangitis with multiple liver abscesses in a patient with lung squamous cell carcinoma: A case report
Authors: Jingu Daisuke , Horii Akira , Yajima Takehiro , Ohira Ryuta , Ubukata Satoshi , Satou Kosuke , Takahashi Hiroshi , Watanabe Hiroshi , Funayama Hiroyuki 
Published: March 2024

AbstractA 76‐year‐old man underwent an operation for lung squamous cell carcinoma in the right lower lobe, followed by initial adjuvant therapy with atezolizumab, an antibody against anti‐programmed death‐ligand 1 (PD‐L1). On day 4 after atezolizumab treatment, the patient developed general malaise and fatigue. He was diagnosed with atezolizumab‐induced sclerosing cholangitis. Steroid treatment was started, and patient's condition, including symptoms, laboratory data and imaging findings, improved. Antibiotic treatments were ended on day 40, and the steroid dose was gradually reduced. Multiple liver abscesses were observed on day 106, and another treatment with antibiotics became necessary. The patient eventually recovered from liver abscesses. Sclerosing cholangitis induced by immune checkpoint inhibitor is rare, and the long‐term clinical data about this adverse effect is limited. Hence, we think it is important to raise an alarm over sclerosing cholangitis coupled with liver abscesses after immunosuppressive therapy.
Fixed‐time sliding mode trajectory tracking control for marine surface vessels under mismatched conditions and input saturation
Authors: Zhang Jingqi , Yu Shuanghe , Yan Yan , Zhao Ying 
Published: March 2024

SummaryThis paper addresses a trajectory tracking control problem for marine surface vessels (MSVs) in the presence of mismatched conditions and input saturation. Firstly, an MSV model under mismatched conditions is established to solve the problem of unreasonable modeling methods in the existing literature. Secondly, fixed‐time disturbance observers (FXDOs) are designed, where the designed FXDOs not only avoid selecting complicated parameters but also has simple structures, and the disturbance estimation errors can converge to the origin within a setting time. Thirdly, based on the FXDOs and an anti–saturation auxiliary dynamic system, a trajectory tracking control scheme in the presence of mismatched conditions and input saturation is constructed by virtue of fixed‐time integral sliding mode control (SMC), and the actual tracking error signals are uniformly fixed‐time bounded rather than finite‐time one. Fourthly, in order to decrease theoretical calculation values of the original setting time in fixed‐time control, the new setting time under three different parameter conditions is derived, and thus reducing the conservatism. Finally, the simulation results are provided to show the effectiveness and superiority of the designed tracking control scheme.
Commercial Wheat and Oat Flour Derived Fluorescent Carbon Quantum Dots through Sustainable Hydrothermal Synthesis and Their Biological Activities
Authors: Kuppusamy Palaniselvam , Kim Sujung , Park Myunghum , Song Ki‐Duk 
Published: March 2024

AbstractIn this study, we utilized processed edible commercial wheat and oat flours to synthesize highly fluorescent carbon dots using green hydrothermal synthesis. The as‐synthesized carbon quantum dots (CQDs) were characterized using UV‐vis spectrophotometry, photoluminescence spectrophotometry, high‐resolution transmission electron microscopy, and Fourier transform infrared spectroscopy. The synthesized wheat‐CQDs (W‐CQDs) and oat‐CQDs (O‐CQDs) had monodispersed spherical shapes with average sizes of 3–8 and 5–10 nm, respectively, and exhibited strong fluorescence intensity and excitation‐dependent photoluminescence. The W‐CQDs and O‐CQDs were highly dispersed in aqueous solutions and exhibited bright green and blue fluorescence, respectively, under UV light (λex=380 and 370 nm). Both CQDs contained abundant functional groups, including amino, hydroxyl, and carboxyl groups, which may play a major role in biological applications. The W‐CQDs and O‐CQDs showed good free‐radical scavenging capacity in the 2,2‐diphenylpicrylhydrazyl (DPPH) and H2O2 assays. The anti‐inflammatory activities of W‐CQDs and O‐CQDs were more effective than that of the standard, with EC50 values of 1.8 and 1.3 mg/mL, respectively, in the protein denaturation assay. Additionally, the CQDs exhibited low cytotoxicity toward NIH3T3 fibroblast and human HeLa cervical cancer cells when treated with a 5‐mg/mL concentration. Therefore, green‐synthesized W‐CQDs and O‐CQDs are easily available, less cytotoxic, and applicable to therapeutic and cell nanocarrier purposes.
In‐suit synthesis of FeP/C/CNT composites with excellent performance in supercapacitors and lithium‐ion batteries
Authors: Liu Yongdong , Gao Shiyao , Zhang Deyi , Niu Xiaohui , Li Hongxia , Wang Kunjie 
Published: March 2024

AbstractIron phosphide (FeP) is a promising electrochemical energy storage material due to easy to obtain and high theoretical capacity. However, the intrinsic poor conductivity and the large volume change during charging and discharging process, result in a sharp decline in capacity and short cycle life for FeP. In this work, the FeP/C/CNT nanocomposite was synthesized efficiently and conveniently by one‐step solid‐phase synthesis method. Amorphous carbon‐coated FeP particles are embedded in a three‐dimensional network structure composed of highly conductive carbon nanotubes, drastically enhancing the conductivity of FeP and reducing the volume expansion during charging and discharging. In the three‐electrode system, the FeP/C/CNT composites showed good electrochemical performance, with a specific capacity as high as 124.4 mAh g−1 at 1 A g−1. Meanwhile, the constructed Ni2P@C/CNT//FeP/C/CNT asymmetric supercapacitor delivered a high energy density (70.73 Wh kg−1), power density (7.9 kW kg−1) and a long cycle life (10000 cycles). In addition, as served as an anode material in the lithium ion battery, the FeP/C/CNT composite also displayed as high as 601.8 mAh g−1of specific capacity at 0.1 A g−1 and a good cycle stability, showing superior electrochemical performance. The above work provides a promising composite material for supercapacitors and lithium ion batteries. Moreover, the solid‐state preparation methods can provide a reference for the synthesis of transition metal phosphides.
Influence of hybrid filler on charge conduction and storage performance of polyvinyl chloride/nitrocellulose blend for hybrid electrolyte application
Authors: Jadhav Pratibha S. , Joshi Girish M. 
Published: March 2024

AbstractPolymer blends of polyvinyl chloride/nitrocellulose/MoS2‐Nafion (PVC/NC/MoS2‐Nafion) were prepared using a casting technique. FTIR analysis revealed chemical interactions between the polymer matrix and filler. XRD analysis was employed to investigate changes in structural phases, while SEM illustrated the agglomerated morphology of the modified blends. The critical role of ionic interaction between Nafion and polymer system in enhancing electrical properties was confirmed through impedance analysis. The introduction of oxygenated functionalities improved surface topography and roughness, as observed by AFM. Electrical conductivity increased from 10−6 S/cm to 10−4 S/cm, accompanied by a decrease in activation energy (Ea). The addition of Nafion decreased bulk resistance, indicating enhanced ionic mobility, as supported by impedance analysis. TG‐DSC analysis demonstrated that MoS2 and Nafion improved thermal properties of polymer blends. The glass transition temperature (Tg) increased by approximately 13 °C and 21 °C with MoS2 and Nafion, respectively. Universal testing machine (UTM) results indicated moderate tensile strength and Young's modulus achieved by MoS2 and Nafion. With increasing Nafion loading, elongation at break rose to around 71 %, showcasing excellent interfacial interaction in polymer‐filler system. The resulting polymer blends, modified by Nafion, exhibited high ionic/electrical conductivity and show promise for hybrid polymer electrolyte applications.
Crystalline water induced nonpolar‐to‐polar transition and high piezoelectric response in lamivudine hydrate crystal
Authors: Shi Yu , Weng Yan‐Ran , Zhou Feng , Yu Yun‐Hui , Song Xian‐Jiang , Ai Yong 
Published: March 2024

AbstractElectromechanically converted piezoelectric materials have great applications in actuators, sensors, and energy harvesters. Organic piezoelectric materials are environmentally friendly, easy to prepare, and have a low molecular mass compared to conventional inorganic piezoelectric materials. Here, we present an organic hydrogen bonding piezoelectric material, lamivudine hydrate, which crystallized in the P21 space group at room temperature and exhibits a decent d33 value of 21 pC N−1. This value is comparable to that of the commercial piezoelectric material, Tri‐Glycine Sulfate (TGS, d33=22 pC N−1). Moreover, lamivudine hydrate possesses a superior g33 value of 826×10−3 V m N−1, which is much higher than that of commercial TGS and most of the piezoelectric ceramics. While the lamivudine crystal was refined in the P43212 space group, showing no piezoelectric activity. The presence of crystalline water plays a crucial role in establishing its polar structure and achieving high piezoelectric properties of lamivudine hydrate crystal. The decent d33 and g33 values make it a promising candidate for advanced materials in high‐performance piezoelectric sensors, particularly in applications involving flexible, wearable, and biomechanical devices.
Unveiling the Suppressive Potential of Phenolic Compounds on Bovine Milk Lactoperoxidase
Authors: Gerni Serpil , Öztürk Cansu , Kılınç Namık , Özdemir Hasan , Küfrevioğlu Ö. İrfan 
Published: March 2024

AbstractLactoperoxidase (LPO) is a crucial enzyme found in milk, tears, and saliva, protecting newborns from harmful microorganisms. This study examined the effects of phenolic substances (naringin, morin, esculin, homovanillic acid, and phloridzin) on purified LPO. LPO was purified from bovine milk using affinity chromatography, yielding 66.6 % with a purity of 387.5‐fold. Three methodologies were employed to assess inhibitory properties: spectrophotometric techniques, molecular docking, and MM‐GBSA. The compounds′ IC50 values were 0.0024 μM, 0.0315 μM, 0.0373 μM, 0.0506 μM, and 0.0221 μM, while their Ki values were 0.0059±0.0012 μM, 0.0672±0.0247 μM, 0.0973±0.0369 μM, 0.0664±0.0190 μM, and 0.0470±0.0159 μM, respectively. Naringin exhibited the most potent inhibitory effect, competitively inhibiting LPO. Therefore, naringin could serve as a novel reversible LPO inhibitor.
Preparation and sodium storage properties of spinel‐type (Cr0.2Fe0.2Mn0.2Ni0.2Co0.2)3O4/rGO
Authors: Li Kaixiang , Li Huijun , Zhao Zhenxin , Wang Xiaomin 
Published: March 2024

AbstractWhile conventional oxides have a high theoretical specific capacity, they also suffer from severe volume expansion during cycling, which seriously affects the stability of the structure. Hence, high‐entropy oxide nanoparticles (Cr0.2Fe0.2Mn0.2Ni0.2Co0.2)3O4, CFMNC) were synthesized and uniformly dispersed on reduced graphene oxide(rGO) carriers using a solvothermal method‐assisted heat treatment as a novel sodium‐ion batteries anode material. The introduction of rGO does not change the crystal structure of CFMNC material, while loading CFMNC into the sheet structure of rGO forms a highly conductive structure, which promotes electron/ion transfer. The high specific surface area is conducive to the full infiltration of the electrode material with the electrolyte, and improve the electrode activity. The random distribution of individual metal ions in CFMNC makes itself have a strong entropy‐driven structural stabilization effect to achieve the cycling stability: 149.1 mAh g−1 can be maintained at 100 mA g−1 over 200 cycles with capacity decay rate of 0.05 % cycle−1. CFMNC/rGO also have excellent rate capability (76.1 mAh g−1at 3000mAg−1, and returned to 153.6 mAh g−1at 200 mA g−1 with almost 100 % capacity retention). Therefore, the composite is considered to offer research potential for the design of high‐performance anode materials through entropy‐driven strategies.
Aptamer‐Based Colorimetric Detection of Oxytetracycline by a LSPR‐Based Assay of Gold Nanorods in Honey Sample**
Authors: Mehrabi Fatemeh , Dadmehr Mehdi , Ranjbar Bijan , Hosseini Morteza 
Published: March 2024

AbstractOxytetracycline (OTC) as the frequently applied antibiotics present in human and animal diets and its residue may results to various toxic effects. So, there is a crucial need for developing sensitive method for detection of OTC. Aptamer‐based biosensors (aptasensors) are frequently used in recent applied detection strategies with high affinity and specificity. In the present study, a colorimetric aptasensor was developed for detection of oxytetracycline (OTC) based on aggregation of aptamer functionalized AuNRs. The synthesized AuNRs were characterized and functionalized with specific DNA oligonucleotide as the aptamer to generate an optical signal after binding to the OTC antibiotic. The sensitivity of optical changes in spectroscopic analysis was improved under ambient temperature that resulted in aptamer folded structure and subsequent aggregation state of AuNRs. The longitudinal surface plasmon resonance (LSPR) of AuNRs was decreased in the linear range of applied OTC concentration from 0.1 nM to 100 nM with a detection limit of 0.04 nM. The proposed method was facile and showed sensitive and selective results, that would be consider as an alternative and efficient approach toward rapid detection of OTC.