bluuebunny/crossref_metadata_2025_split huggingface dataset:
Estetika Bentuk Pertunjukan Tari Kuda Lumping Satriyo Wibowo Kecamatan Kranggan Kabupaten Temanggung
Authors: Sa'ati Zuni Lailis , Indriyanto Indriyanto 
Published: March 2024

Tari Kuda lumping adalah tari yang menggambarkan kelompok orang yang sedang naik kuda maupun menggambarkan gerak kuda. Pertunjukan tari Kuda Lumping Satriyo Wibowo Temanggung mengandung nilai estetis yang khas, yaitu terdapat pada pola pertunjukan dan elemen pertunjukan. Penelitian ini bertujuan untuk mengetahui dan mendeskripsikan bentuk dan nilai estetis tari Kuda Lumping Satriyo Wibowo Temanggung. Metode penelitian yang digunakan adalah metode penelitian kualitatif dengan pendekatan yang digunakan adalah pendekatan deskriptif kualitatif, estetis koreografis serta etik dan emik. Pengumpulan data dalam penelitian ini menggunakan metode pengumpulan data lapangan dan pengumpulan data pustaka serta menggunakan teknik observasi,wawancara dan dokumentasi. Hasil penelitian menyatakan bahwa estetika bentuk pertunjukan tari Kuda Lumping Satriyo Wibowo nampak pada pola pertunjukannya yang terdiri dari bagian awal, bagian inti, bagian akhir dan elemen pertunjukan yang terdiri dari tema, gerak, penari, pola lantai, tata rias dan busana, musik tari, tata teknik pentas. dan property. Tari kuda lumping Satriyo Wibowo memiliki nilai keindahan yang khas yang dapat dilihat dari bentuk pertunjukan dan elemen-elemen pendukung pertunjukan. Tari Kuda Lumping ini menampilkan gerak yang bertekanan kuat, volume besar, tempo cepat sehingga terkesan gagah dan energik.
Un cotejo indispensable para el estudio de Insensatez, de Horacio Castellanos Moya
Authors: Dávila Jesús 
Published: March 2024

The hypothesis developed by this paper is that the document corrected and quoted by the narrator of Insensatez is not a faithful copy of the report Guatemala: Nunca más. The first reception of the novel in Spain is reconstructed, as the origins of a reading bias that tends to identify and confuse the historical document with that of fiction are traced; likewise, biographical data of Castellanos Moya relevant to the reading of Insensatez are analyzed. Finally, the most important critical contributions on the subject are discussed and two specific collations are presented to argue the central hypothesis of this work.
Nonbiliyer Akut Pankreatit Prognozunda Skorlama Sistemlerinin Tanısal Performansı: Ranson ve Balthazar Skorlarının Karşılaştırmalı Analizi
Authors: Aladağ Nazire , Tuna Müjgan , Akın Seydahmet 
Published: March 2024

Amaç: Akut pankreatitli hastalarda ciddiyetin ve prognozunu tahmin edilmesinde Ranson skoru (RS) ve Balthazar Bilgisayarlı Tomografi Şiddet İndeksini (CTSI) yaygın olarak kullanılmaktadır. Ancak, bu skorlama sistemlerinin biliyer olmayan akut pankreatitin prognouzu tahmin etmedeki tanısal üstünlükleri belirsizliğini korumaktadır. Bu nedenle, bu çalışmada nonbiliyer AP'nin prognozunu tahmin etmede RS ve CTSI'yi karşılaştırmayı amaçladık.
Gereç ve Yöntemler: Bu retrospektif çalışmaya, Ocak 2021 ile Mayıs 2023 arasında İç Hastalıkları kliniğinde takip edilen 67 nonbiliyer AP hastası dahil edildi. RS ve CTSI, hastaların laboratuvar ve radyolojik bulgularına dayanarak hesaplanmıştır. Son noktalar, uzun süreli hastanede yatış (≥8 gün), komplikasyonlar ve mortaliteden oluşmaktadır.
Bulgular: Hastaların ortalama yaşı 50.1±8.3 yıl olup, çoğunluğu erkek (%59.7) idi. Hastaların %11.9'unda komplikasyon gelişti, %26.9'unda uzun süreli hastanede yatış meydana geldi ve %6'sında ölüm gözlendi. Uzun süreli hastanede yatış ve komplikasyon riskini tahmin etmede CTSI, RS'ye göre üstün tanısal performans sergiledi (uzun süreli hastanede kalma için eğri altındaki alan (AUC) = 0.590 vs. 0.856, p
Use of Artificial Intelligence in the Activities of Religious Associations and Control Over Them
Authors: Popova S. S. 
Published: March 2024

Objective: to identify gaps and formulate proposals on legal regulation of the use of artificial intelligence in the activities of religious associations and control (supervision) over them.Methods: the study is based on sectoral and risk-oriented approaches, formal-logical and comparative general scientific methods, as well as on the method of legal forecasting.Results: the author noted similarity of ethical principles formulated all over the world in the sphere of artificial intelligence development and application, as well as their general shortcomings, namely, the lacking consideration of the specificity in certain spheres of human life (religious sphere), cultural peculiarities, historical development of a country and people. The shortcomings of principles stipulated by the codes of ethics include their recommendatory nature, which creates a basis for abusing them in certain cases. The author proposes that if control and supervisory authorities caused harm while using artificial intelligence, the relevant public authority should be recognized as liable and obliged to compensate for the harm caused.Scientific novelty: the paper summarizes the practice of religious associations using AI, formulates current and prospective directions of the use of artificial intelligence by religious associations, and makes proposals for the AI use in controlling (supervising) religious associations’ activities.Practical significance: the main conclusions and proposals can be used for the improvement of legislation on religious associations’ activities and control (supervision) over them, as well as for developing legal regulation of the AI use in control and supervision activities. The author identified the possibilities for religious associations using AI to popularize religion, inform about their activities, manage property, analyze sacred texts to improve their understanding and interpretation, as well as for conducting scientific research, systematization and accumulation of information, preservation of cultural heritage, and educational activities. The use of artificial intelligence in controlling the religious associations’ activities can reduce the period of religious organizations’ registration and inspections and optimize the work of control bodies, including by monitoring the religious situation.
Personal Data in Artificial Intelligence Systems: Natural Language Processing Technology
Authors: Ilin I. G. 
Published: March 2024

Objective: to conceptualize, from the viewpoint of personal data protection legislation, the development of natural language processing technology, identifying possible legal barriers to such development and directions for further research of the issue.Methods: the research is based on general scientific methods of cognition, along with which formal-legal and comparative-legal methods were applied, as well as the method of theoretical modeling.Results: it was found that the observance of personal data regime natural language processing in the development of natural language processing technology leads technology, to a conflict between private-legal and public-legal interests, which, personal data in turn, creates obstacles for further development of this technology. The shortcomings of the existing legal order are shown, namely, the insufficient correspondence to the technical features of technology development. This may lead to the risks of excessive regulation, or, on the contrary, to the risks of neglecting critical areas that require protection. Problems in qualifying the data involved in the technology development are outlined. An attempt is made to define the limits of ensuring the lawfulness of personal data processing within the natural language processing technology. The material, temporal and territorial effect of the legal regulation in this field is identified as the limits of ensuring the legality. The author touches upon the possibility of using personal data as a consideration, which is important for the development of natural language processing technology and for the improvement of the information and communication technology industry.Scientific novelty: the paper supplements the scientific discussion on the legal regulation of personal data processing by artificial intelligence systems with an analysis of natural language processing technology. The latter is insufficiently studied, making it relevant to research information law, namely, the legal relations arising around artificial intelligence systems, and to assess the impact of a personal data regime on the development of natural language processing technology.Practical relevance: the applied aspects of the problems researched and the results obtained can be used to improve the legal regulation of public relations in the field of creation and development of artificial intelligence, as well as to identify and assess the legal risks arising in the personal data processing by developers of digital products based on natural language processing technology.
An Immune Microenvironment-Associated Gene Signature Predicts Outcomes and Therapeutic Response in Pediatric Medulloblastoma
Authors: Han DongMing , Jia Zetian , Wang Ziwei , Chen Xuan , Yang Zhengtao , Zou Wanjing , Liu Raynald , Jiang Yifei , Jin Xin , Hu Yuhua , Qiu Xiaoguang , Li Chunde , Liu Hailong , Li Shuaicheng , Li Jiankang , Jiang Tao 
Published: March 2024

Abstract
Purpose: The tumor microenvironment (TME) is a pivotal factor in the progression and treatment response of cancers, including medulloblastoma (MB), the most common malignant brain tumor in children. This study investigates TME-specific gene signatures to create a prognostic model for MB patient outcomes.
Methods: We sequenced 240 MB patient samples at Beijing Tiantan Hospital with RNASeq and analyzed TME components. Through co-expression network analysis and regression models, we identified an eight-gene signature that correlated with TME elements. This signature was tested against an independent dataset (GSE85217) for validation.
Results: Our study presents the TME-associated risk score (TMErisk), which incorporates the eight-gene (CEBPB, OLFML2B, GGTA1, GZMA, TCIM, OLFML3, NAT1, and CD1C) signature. Higher TMErisk scores were associated with decreased overall survival and lower immune cell infiltration, immune checkpoint activity, and human leukocyte antigen expression. There was also a notable negative correlation between TMErisk scores and both TMB and IPS, varying across MB molecular subtypes. Moreover, the TME-risk was inversely related to the tumor mRNAsi, implying the influence of the TME on tumor stemness.
Conclusions:Our findings identify a TME-specific eight-gene prognostic model that may serve as a predictive biomarker for MB patient outcomes and responses to immunotherapy. This gene signature model offers a supplementary tool to current WHO molecular subtypes and provides a potential target for future TME-focused MB treatment strategies. However, the distinct TME landscapes across MB subtypes pose new challenges for further research.
Keywords: gene signature, immune cells, medulloblastoma, tumor microenvironment, prognostic model, tumor, stromal cells
A Multistage, Multiarmed, Double-Blind Placebo-Controlled Human Transdermal Vitamin D Supplement Study (TransVitD)
Authors: Hibbard Thomas , Andriollo Paolo , Lim Chui Hua , Guo Qing , Lawrence Karl , Coker Bolaji , Malek Rayka , Douiri Abdel , Alhnan Mohamed A , Jones Stuart 
Published: March 2024

Abstract

Background: Life-style changes have meant that it is problematic to maintain adequate vitamin D concentrations in many people across the globe. Given that it's mainly generated by UV-catalysed production in the skin where it uses vitamin D binding protein to facilitate systemic absorption., it is questionable if oral administration of this vitamin is the optimal means to replace it. However, supplementing this oil-soluble vitamin is problematic as it gets stuck in the stratum corneum after topical application. This clinical study will test the ability of a new vitamin D ester, vitamin D phosphate, which is more water-soluble compared to vitamin D, can be administered via a transdermal patch to improve vitamin D status.
Method: This is a two-part study comprising a dose-escalation with the vitamin D phosphate transdermal patch followed by a randomised, double-blind, placebo-controlled, multi-armed, multi-stage clinical trial. It is a single-centred, 12-week study that will enrol a maximum of 100 participants. The blinded, randomised trial will test different dose frequencies for four weeks compared to a placebo, then after an interim analysis, the best dosing frequency will be assessed against a placebo. The dose escalation study will monitor safety and tolerability using serum calcium levels. The primary outcome for the multi-stage clinical study will be the concentration of 25(OH)D3 in the serum (ng/mL) at weeks 4 and 8 compared to baseline. The secondary outcome measures include serum vitamin D binding protein levels, skin interstitial fluid biomarker concentrations, and nail appearance after 4 and 8 weeks compared to baseline.
Discussion: This study will determine if a vitamin D phosphate transdermal patch can improve vitamin D status. In addition, it could provide a better understanding of how vitamin D is absorbed after application directly to the skin by measuring the serum vitamin D binding protein and skin biomarker responses to transdermal supplementation.
Trial Registration: Clinical Trials .gov NCT06098846, registered on 23rd October 2023
Intensive short-term sampling with long-term consequences: characterizing pollutant transport with implications for developing monitoring
Authors: Anderson Elliot , Schilling Keith 
Published: March 2024

Abstract

Riverine sampling of pollutants is commonly used to understand pollutants’ transport pathways, relationships with hydrology, and overall presence in a waterbody. However, gaps between sample collection introduce errors to these efforts, and guidance prescribing sampling frequency remains sparse. The magnitude of error often depends on the type of contaminant and watershed size, making the creation of comprehensive sampling guidance difficult. This study analyzed a unique dataset that measured 18 analytes, including pesticides, nutrients, and pathogens, in three Iowa rivers for 90 consecutive days (May 4 – August 1, 2000). This dataset provided a novel opportunity to relate pollutants to local hydrology and quantify errors associated with recurring sampling.
Pesticide concentrations followed the spring flush phenomenon, where values were greatest during high streamflow in May and June but often depleted by July. Fecal coliform and total phosphorus (TP) also coincided with high flow, but unlike pesticides, their concentrations never diminished. Nitrate exhibited more complex behavior; concentrations were diluted during high flows and then increased as streamflow receded. Autocorrelations were significant for nitrate and atrazine in larger rivers but negligible for fecal coliform and TP.
Loads were calculated for four pollutants with minimal non-detects (atrazine, fecal coliform, nitrate, and TP). We simulated intermittent sampling by selecting evenly spaced subsets of measured values to estimate loads, which were compared to the actual loads to quantify error. This method typically overestimated nitrate loads but underestimated other pollutants, and errors often decreased in larger watersheds. Nitrate generally had the lowest error, while fecal coliform had the highest. We used these results to approximate the sampling frequency needed to bind errors within a certain threshold.
Comparative analysis of electrical conductivity of groundwater from Hand-dug wells and Boreholes in Bida, Nigeria
Authors: Temaugee Samuel Terungwa , Kudu Hauwa Mohammed , Daniel Theresa Avusuahi , Umar Abubakar , Akano Benedict Ubawuike , Lasisi Akangbe Ramoni , Dania Clement Majebi , Arzika Yusuf Koko , Dangana Abubakar Idris , Abdullahi Mohammed 
Published: March 2024

Abstract
The human body is composed of three-quarters of water, emphasizing the significant influence of water quality on our health. Consequently, it is essential to assess water quality in each lithologically distinct region. This research aimed to assess the Electrical Conductivity (σ) of water from Hand-dug Wells and Boreholes in Bida. A total of 40 samples, 20 from each source, were collected from key locations within Bida town. Analysis of the samples was performed using the Jenway DDS-307 conductivity meter, a versatile digital device adaptable to temperature changes through a probe. The mean values for Hand-dug Wells ranged from (260.00 ± 8.02) - (1335.67 ± 40.60) μS.cm−1. Borehole mean σ values varied from (33.53±0.67) - (1485.33±7.37) μS.cm−1. Among the 40 sampled Wells, nine (9) exceeded the benchmark, while six (6) approached the benchmark of 1000 μS.cm−1 specified by the Standard Organization of Nigeria (SON) and the World Health Organization (WHO) for drinking water. Consequently, in terms of σ as a drinking water standard, this study recommends that 15 sources (both Hand-dug and Boreholes) are unsuitable for drinking but may be utilized for other purposes. The study also suggests further investigation of physico-chemical parameters and radionuclide concentration of groundwater in Bida town.
Fast-Food Consumption Intention among High School Students in Bangladesh
Authors: Islam Md. Ariful , Khatun Shanzida , Begum Taslima , Khatun Fahima 
Published: March 2024

Abstract
Background: Intention to Fast Food Consumption among children and adolescents has been recognized as a serious health concerns globally.
Objective: The objective of the study was to identify factors influencing student’s intentions toward fast food consumption.
Methods: A correlational study was conducted using a convenience sampling technique. Participants included high school students in grades 9th to 10th from two selected schools. Data were collected through a self-administered questionnaire. Descriptive and inferential statistics were used for data analysis.
Results: The average age of the students was 15.32 years. The intention to consume fast food was negatively correlated with the students' age (r=-.281, p<.001) and female students had a higher intention to consume fast food (t =-5.386, p<.001). The results showed a statistically significant relationship that the higher scores of attitudes, subjective norms, and perceived behavioral control were positively correlated with higher intention to fast food consumption (p<.05) respectively. Further analysis showed that attitude and perceived behavioral control were the significant predictors of intention to consume fast food (ꞵ=.296, p<.001), and (ꞵ=.478, p<.001) together explained 42% of the variance in the intention to consume fast food among students.
Conclusion: The findings of this study provide baseline information for policymakers to develop strategies following effective health education programs to raise awareness of attitudes among students. Further studies should examine the constructive ways of changing attitudes and reasonable alternatives to alter perceived behavioral control regarding the intention to fast food consumption.
Process Development of Fibre-Cement Flat Sheets by Young and Mature Coconut Fibres Replaced Asbestos for Eco-Friendly Products
Authors: Khamput Prachoom , Klathae Tawich , Choosakul Chookiat , Dueramae Saofee 
Published: March 2024

Abstract

This study investigated the young and mature coconut fibres as asbestos replacement in fibre- cement flat sheet. The ratio of fibre content was ranged from 5–9.5% with an increment of 0.5% by weight of binder. Moreover, crushed rock dust (CRD) was also utilized in this study at ratio of 50% as sand replacement. The results showed that the addition of young coconut fibre (YCF) and mature coconut fibre (MCF) in flat sheet increased with the decreasing of bulk density and thermal conductivity. The optimum fibre content was used at 6.5-7% by weight of binder for two types of fibre with the highest flexural strength of 12–13 MPa. Especially, the modulus of rupture and density of fibre- cement flat sheet used YCF were higher than that of fibre- cement flat sheet used MCF, which is clarified by SEM results due to denser structure of MCF. Moreover, the modulus of rupture was directly proportional to the modulus of elasticity in fibre- cement flat sheet.
The prognostic and immune significance of SLAMF9 in pan-cancer and validation of its role in colorectal cancer
Authors: zhao chunmei , zhu xingjia , dong qingyu , sun jing , Sun Baolan , Wang Guihua , wang xudong 
Published: March 2024

Abstract

SLAMF9 is a member of the family of conserved lymphocyte activation molecules (SLAMF), Unlike other SLAMs, which have been extensively studied, investigations on SLAMF9 have primarily concentrated on an individual or limited number of types of cancers, but without systematic investigation across different cancer types. Through systematic pan-cancer analysis, we demonstrated that SLAMF9 expression was increased in a variety of tumor tissues, and that overexpression of this protein may lower patient survival in the majority of malignancies. Furthermore, as per the correlation analysis the expression of SLAMF9 was strongly correlated with the expression of numerous immune cell infiltrates, immune checkpoint inhibitors, tumor mutation load, and microsatellite instability. More importantly, the expression of SLAMF9 is highly correlated with epithelial-mesenchymal transition (EMT) score. Additionally, it was demonstrated through cell-based research that SLAMF9 knockdown may lessen the proliferative activity, cell motility, and invasion potential of CRC cells. A nude mouse xenograft model showed that suppressing of SLAMF9 expression could considerably slow tumor growth. Therefore, the results of this study indicated that SLAMF9 can be exploited as a potential prognostic and therapeutic biomarker of tumors and it may have a substantial role in the proliferation as well as migration of CRC cells.
4-furanylvinylquinoline derivative as a new scaffold for the design of oxidative stress initiator and glucose transporters inhibitor drugs
Authors: Kuczak Michał , Cieślik Wioleta , Musioł Robert , Mrozek-Wilczkiewicz Anna 
Published: March 2024

Abstract

In the present work, a detailed analysis of the effect of a substitution at the C4 position of the quinoline ring and substituents on the structure-antitumour activity relationship was conducted. After analysing a library of derivatives from the styrylquinoline and furanylvinylquinoline groups, we selected the most active (IC50 below 100 nM) derivative 13 that contained the strongly electron-withdrawing nitro group in the furan substituent. The mechanism of action of this compound has been studied on cell lines that differ in their p53 protein status. For this derivative, both cell cycle arrest and the induction of apoptosis were revealed. These studies were then confirmed by other methods at the gene and protein levels. Interestingly, we observed differences in the mechanism of action depending on the presence and mutation of the p53 protein, thus confirming its key role in the cellular processes. Incubation with derivative 13 resulted in the induction of oxidative stress and triggered a cascade of cellular defence proteins that failed in the face of such an active compound. In addition, the results showed an inhibition of the glucose transporter, which is extremely important in the context of anti-cancer activity.