bluuebunny/crossref_metadata_2025_split huggingface dataset:
A Novel Synthesis of (β‐Organochalcogenyl)allyl Phenyl Sulfoxides via Regioselective Hydrochalcogenation Reaction of 1,2‐Allenyl Sulfoxides.
Authors: Wu Zhimeng , Shen Ruwei , Ren Lianjun , Huang Xian 
Published: November 2005

AbstractFor Abstract see ChemInform Abstract in Full Text.
An Acid Catalyzed Intramolecular C—C Coupling Reaction of 8‐Halomethyl‐16‐methoxy[2.2]metacyclophanes.
Authors: Tanaka Kan , Miyazawa Akira , Hiate Ai , Tashiro Masashi , Saisyo Tatsunori , Okabe Ryo , Kohno Kazufumi , Yamato Takehiko 
Published: November 2005

AbstractFor Abstract see ChemInform Abstract in Full Text.
A New Class of High Affinity Thyromimetics Containing a Phenyl‐naphthylene Core.
Authors: Hangeland Jon J. , Friends Todd J. , Doweyko Arthur M. , Mellstroem Karin , Sandberg Johnny , Grynfarb Marlena , Ryono Denis E. 
Published: November 2005

AbstractFor Abstract see ChemInform Abstract in Full Text.
Stereospecific Isomerization of 2‐(1‐Bromoalkyl)‐1‐sulfonylaziridines Using Magnesium Bromide.
Authors: Karikomi Michinori , Takayama Takeshi , Haga Kazuo , Hiratani Kazuhisa 
Published: November 2005

AbstractFor Abstract see ChemInform Abstract in Full Text.
Sulphamic Acid — A Mild, Efficient, and Cost‐Effective Solid Acid Catalyst for the Synthesis of Bis(1H‐indol‐3‐yl)methanes.
Authors: Singh Pankajkumar R. , Singh Devendrapratap U. , Samant Shriniwas D. 
Published: November 2005

AbstractFor Abstract see ChemInform Abstract in Full Text.
A Novel TFA‐Mediated cyclo‐Dimerization of 1‐Substituted 3‐Alkenylindole Derivatives to Cyclopent[b]indoles.
Authors: Kawasaki Ikuo , Terano Masami , Kurume Ai , Hara Satoko , Yamashita Masayuki , Ohta Shunsaku 
Published: November 2005

AbstractFor Abstract see ChemInform Abstract in Full Text.
General Synthesis of (1‐Substituted‐1H‐1,2,3‐triazol‐4‐ylmethyl)‐dialkylamines via a Copper(I)‐Catalyzed Three‐Component Reaction in Water.
Authors: Yan Ze‐Yi , Zhao Ya‐Bin , Fan Ming‐Jin , Liu Wei‐Min , Liang Yong‐Min 
Published: November 2005

AbstractFor Abstract see ChemInform Abstract in Full Text.
Mild and Efficient Method for the Synthesis of Tetrahydropyran Derivatives via Cross‐Cyclization Between Epoxides and Homoallylic Alcohols Mediated by Bismuth(III) Chloride.
Authors: Yadav J. S. , Rajasekhar K. , Murty M. S. R. 
Published: November 2005

AbstractFor Abstract see ChemInform Abstract in Full Text.
A Convenient Preparation of Xanthene Dyes.
Authors: Yang Youjun , Escobedo Jorge O. , Wong Alexander , Schowalter Corin M. , Touchy Michael C. , Jiao Lijuan , Crowe William E. , Fronczek Frank R. , Strongin Robert M. 
Published: November 2005

AbstractFor Abstract see ChemInform Abstract in Full Text.
8‐Piperazinyl‐2,3‐dihydropyrrolo[3,2‐g]isoquinolines: Potent, Selective, Orally Bioavailable 5‐HT1 Receptor Ligands.
Authors: Heightman Tom D. , et al. et al. 
Published: November 2005

AbstractFor Abstract see ChemInform Abstract in Full Text.
Facile, One‐Pot Synthesis of Bicyclic 2‐Pyridones from Acyl Isocyanates, N‐Phenylmaleimide and Trimethylsilyldiazomethane.
Authors: Hari Yoshiyuki , Iguchi Tomoe , Aoyama Toyohiko 
Published: November 2005

AbstractFor Abstract see ChemInform Abstract in Full Text.
Synthesis of Indeno‐Fused Derivatives of Quinolizinium Salts, Imidazo[1,2‐a]pyridine, Pyrido[1,2‐a]indole, and 4H‐Quinolizin‐4‐one via Benzannulated Enyne—Allenes.
Authors: Dai Weixiang , Petersen Jeffrey L. , Wang Kung K. 
Published: November 2005

AbstractFor Abstract see ChemInform Abstract in Full Text.
Synthesis of 4‐Aryl‐7,7‐dimethyl‐1,2,3,4,5,6,7,8‐octahydroquinazoline‐2‐one/thione‐5‐ one Derivatives and Evaluation as Antibacterials.
Authors: Kidwai M. , Saxena S. , Khan M. Khalilur Rahman , Thukral S. S. 
Published: November 2005

AbstractFor Abstract see ChemInform Abstract in Full Text.
A New Approach to 1‐Substituted‐1,2‐alkadiene‐phosphonates. Part 3. Synthesis of 2‐Keto‐5‐methyl‐3,4‐hexadienyl‐3‐phosphonate Dimethyl Esters.
Authors: Enchev D. D. 
Published: November 2005

AbstractFor Abstract see ChemInform Abstract in Full Text.
A Monoterpene Glucoside and Three Megastigmane Glycosides from Juniperus communis var. depressa.
Authors: Nakanishi Tsutomu , Iida Naoki , Inatomi Yuka , Murata Hiroko , Inada Akira , Murata Jin , Lang Frank A. , Iinuma Munekazu , Tanaka Toshiyuki , Sakagami Yoshikazu 
Published: November 2005

AbstractFor Abstract see ChemInform Abstract in Full Text.
New Bicyclic Taxane Diterpenoids from Taxus sumatrana.
Authors: Shen Ya‐Ching , Hsu Shaw‐Man , Lin Yun‐Sheng , Cheng Kuen‐Ching , Chien Ching‐Te , Chou Chang‐Hung , Cheng Yuan‐Bin 
Published: November 2005

AbstractFor Abstract see ChemInform Abstract in Full Text.
Molecular Complexity from Aromatics: Synthesis and Photoreaction of endo‐Tricyclo[5.2.2.02,6]undecane — A Stereoselective Route to Tricyclic Framework of Protoilludanes.
Authors: Singh Vishwakarma , Lahiri Sanjoy , Pal Shantanu 
Published: November 2005

AbstractFor Abstract see ChemInform Abstract in Full Text.
ZHD‐0501, a Novel Naturally Occurring Staurosporine Analogue from Actinomadura sp. 007.
Authors: Han Xiao‐Xian , Cui Cheng‐Bin , Gu Qian‐Qun , Zhu Wei‐Ming , Liu Hong‐Bing , Gu Jing‐Yan , Osada Hiroyuki 
Published: November 2005

AbstractFor Abstract see ChemInform Abstract in Full Text.
Potent Inhibitory Effects of N‐Aryl S‐Alkylthiocarbamate Derivatives on the Dopa Oxidase Activity of Mushroom Tyrosinase.
Authors: Lee Kun Ho , Koketsu Mamoru , Choi Sang Yoon , Lee Kang Jin , Lee Pyeongjae , Ishihara Hideharu , Kim Sun Yeou 
Published: November 2005

AbstractFor Abstract see ChemInform Abstract in Full Text.
β‐1,3‐Glucan Polysaccharides as Novel One‐Dimensional Hosts for DNA/RNA, Conjugated Polymers and Nanoparticles
Authors: Sakurai Kazuo , Uezu Kazuya , Numata Munenori , Hasegawa Teruaki , Li Chun , Kaneko Kenji , Shinkai Seiji 
Published: November 2005

AbstractFor Abstract see ChemInform Abstract in Full Text.
Reduction of Nitric Oxide over Rutile‐supported Cu Surfaces: A Quantum Chemical Study
Authors: Tan Kai , Lin Meng‐Hai , Wang Nan‐Qin , Zhang Qian‐Er 
Published: November 2005

AbstractThe adsorption and decomposition of NO on the stoichiometric rutile‐supported Cu surfaces have been studied by means of density functional calculations with an embedded cluster model. The calculation results indicate that NO is favorably adsorbed as O‐down and could easily attach another NO molecule to form N2O intermediate or directly be dissociated into N2 and O2. On the basis of the calculated energetics, possible mechanism of NO decomposition reaction has been proposed.
Synthesis, Luminescence and Electrochemical Properties of Two Phenothiazine Derivatives
Authors: Li Dong‐Mei , Zhou Hong‐Ping , Pu Ji‐Qin , Feng Xiao‐Jun , Wu Jie‐Ying , Tian Yu‐Peng , Yu Xiao‐Qiang , Tao Xu‐Tang , Jiang Min‐Hua 
Published: November 2005

AbstractThe synthesis, luminescence and electrochemical properties of two novel phenothiazine derivatives were presented, which exhibit good one‐photon fluorescence emission. The quantum yields and solvent effects of them were studied in detail. Compound 3,7‐bis(2‐4′‐imidazolylbenzylidenehydrazonoethyl)‐(0‐ethylphenothiazine) (5) was used as an effective initiator, of which two‐photon fluorescence spectra were investigated under 800 nm fs laser pulse and the measured two‐photon absorption cross‐section was 18×10−50 cm4·s per photon. Two‐photon initiated polymerization microfabrication experiments were carried out. X‐ray diffraction analyses revealed that the shape of the compound 3,7‐bis(2‐pyrid‐4′‐ylmethylidenehydrazonoethyl)‐(0‐ethylphenothiazine) (4) looks like a butterfly with nearly planar wings. The dihedral angle of the two benzene rings is 37.6° and there is an obvious π‐π stacking interaction between the molecules in the crystal.
Determination of the Specific Heat Capacity of RE(Et2dtc)3(phen) by Microcalorimetry
Authors: Ge Hong‐Guang , Jiao Bao‐Juan , Shuai Qi , Liu Ming‐Yan , Chen San‐Ping , Hu Rong‐Zu , Gao Sheng‐Li 
Published: November 2005

Abstract A calculation formula for determining the specific heat capacity of solid compound with an improved RD496‐III microcalorimeter was derived. The calorimetric constant and precision determined by the Joule effect were (63.901±0.030) µV/mW and 0.3% at 298.15 K, respectively, and the total disequilibrium heat has been measured by the Peltier effect. The specific heat capacities of two standard substances (benchmark benzoic acid and α‐Al2O3) were obtained with this microcalorimeter, and the differences between their calculated values and literature values were less than 0.4%. Similarly, the specific heat capacities of thirteen solid complexes, RE(Et2dtc) 3(phen) (RE=La, Pr, Nd, SmLu, Et2dtc: diethyldithiocarbamate ion, phen:1,10‐phenanthroline) were gained, and their total deviations were within 1.0%. These values were plotted against the atomic numbers of rare‐earth, which presents tripartite effect, suggesting a certain amount of covalent character in the bond of RE3+ and ligands, according to Nephelauxetic effect of 4f electrons of rare earth ions.
Research on Inorganic Anion Recognition of Calix[4]pyrroles and Dipyrrylmethanes by Capillary Zone Electrophoresis
Authors: Zhou Chang‐Zheng , Qiu Hong‐Deng , Guo Yong , Jiang Sheng‐Xiang 
Published: November 2005

AbstractCapillary electrophoresis (CE) can separate charged and neutral substances with high speed and efficiency. In this paper, utilizing meso‐octamethylcalix[4]pyrrole, meso‐tetraspirocyclohexylcalix[4]pyrrole, bimethyl bi(2‐pyrryl)‐methane and 1,1‐bi(2‐pyrryl)cyclohexane as additives in capillary zone electrophoresis (CZE) electrolyte, their recognition ability to inorganic anions was discussed. The dipyrrylmethanes have better recognition ability than others. Their effects on separation of seven normal inorganic anions by CZE were studied.
Synthesis and Pharmacological Evaluation of Novel Conjugates of Indomethacin with Antioxidant Activity
Authors: Zhang Yi‐Chun , Chen Ping‐Tao , Guan Hua‐Shi , Li Ying‐Xia 
Published: November 2005

AbstractA series of new conjugates of indomethacin with phenolic antioxidants were synthesized for enhanced antiinflammatory activity as well as reduced ulcerogenic potency. It was found that all conjugates were very potent antioxidants in vitro. They could inhibit lipid peroxidation significantly, while 11b–11e and 13b–13e could also interact with DPPH. However these conjugates showed little inhibition against croton oil induced mouse ear swelling.
(Bmim)Br3 as a New Reagent for Regioselective Monobromination of Phenols and Several Activated Aromatics under Solvent‐free Conditions
Authors: Le Zhang‐Gao , Chen Zhen‐Chu , Hu Yi 
Published: November 2005

AbstractReaction of phenols and activated aromatics with 1‐butyl‐3‐methylimidazolium tribromide [(Bmim)Br3] under solvent‐free conditions gave selectively the corresponding monobromination products in excellent yields.
Partially overlapping distribution of epsin1 and HIP1 at the synapse: Analysis by immunoelectron microscopy
Authors: Yao Pamela J. , Bushlin Ittai , Petralia Ronald S. 
Published: November 2005

AbstractSynapses of neurons use clathrin‐mediated endocytic pathways for recycling of synaptic vesicles and trafficking of neurotransmitter receptors. Epsin 1 and huntingtin‐interacting protein 1 (HIP1) are endocytic accessory proteins. Both proteins interact with clathrin and the AP2 adaptor complex and also bind to the phosphoinositide‐containing plasma membrane via an epsin/AP180 N‐terminal homology (ENTH/ANTH) domain. Epsin1 and HIP1 are found in neurons; however, their precise roles in synapses remain largely unknown. Using immunogold electron microscopy, we examine and compare the synaptic distribution of epsin1 and HIP1 in rat CA1 hippocampal synapse. We find that epsin1 is located across both sides of the synapse, whereas HIP1 displays a preference for the postsynaptic compartment. Within the synaptic compartments, espin1 is distributed similarly throughout, whereas postsynaptic HIP1 is concentrated near the plasma membrane. Our results suggest a dual role for epsin1 and HIP1 in the synapse: as broadly required factors for promoting clathrin assembly and as adaptors for specific endocytic pathways. J. Comp. Neurol. 494:368–379, 2006. Published 2005 Wiley‐Liss, Inc.
Synaptic connections between eyelet photoreceptors and pigment dispersing factor‐immunoreactive neurons of the blowfly Protophormia terraenovae
Authors: Yasuyama Kouji , Okada Yoshinori , Hamanaka Yoshitaka , Shiga Sakiko 
Published: November 2005

AbstractStudies using various mutants of Drosophila melanogaster bearing defects in their visual system, including those of the retinal and extraretinal photoreceptor systems, have indicated that the extraretinal photoreceptor known as the Hofbauer‐Buchner (H‐B) eyelet plays an active, if subsidiary, role in the entrainment of circadian rhythms. In the present study, in the context of unraveling the function of extraretinal photoreception on circadian rhythms and photoperiodic responses, we searched for extraretinal photoreceptors in the blowfly, Protophormia terraenovae, and found that this fly has a homolog of the H‐B eyelet. In addition, we show morphologically direct synaptic connections between the eyelet of P. terraenovae (called here Pt‐eyelet, after the species' name) and pigment‐dispersing factor (PDF)‐immunoreactive neurons, which are putative circadian pacemaker neurons, by immunogold electron microscopy combined with intracellular dye injection. The Pt‐eyelet was found to reside in the middle of the posterior surface of the optic lobe between the retina and the lamina, as does the H‐B eyelet. This extraretinal photoreceptor was composed of at least four photoreceptor cells equipped with well‐organized microvillar rhabdomeres. Rhodopsin 6‐like immunoreactivity and also the response to light stimuli clearly showed the Pt‐eyelet to be functional. The Pt‐eyelet terminals in the accessory medulla exhibited synaptic bouton‐like appearances and formed divergent multiple‐contact output synapses. Synaptic contacts from the Pt‐eyelet terminal to the PDF‐immunoreactive neurons were identified by the presence of presynaptic ribbons and accumulated synaptic vesicles. Their possible function is discussed in relation to previous studies on circadian rhythm and photoperiodic response of P. terraenovae. J. Comp. Neurol. 494:331–344, 2006. © 2005 Wiley‐Liss, Inc.
Differences in spinal distribution and neurochemical phenotype of colonic afferents in mouse and rat
Authors: Christianson Julie A. , Traub Richard J. , Davis Brian M. 
Published: November 2005

AbstractVisceral pain is a prevalent clinical problem and one of the most common ailments for which patients seek medical attention. Recent studies have described many of the physiological properties of visceral afferents, but not much is known regarding their anatomical characteristics. To determine the spinal distribution and neurochemical phenotype of colonic afferents in rodents, Alexa Fluor‐conjugated cholera toxin‐β (CTB) was injected subserosally into the proximal and distal portions of the descending colon in Sprague Dawley rats and C57Bl/6 mice. Dorsal root ganglia (T10–S2) were processed for fluorescent immunohistochemistry and visualized by confocal microscopy. In the mouse, CTB‐positive neurons were most numerous in the lumbosacral region (LS; L6–S1), with a smaller contribution in the thoracolumbar ganglia (TL; T13–L1). In contrast, CTB‐positive neurons in the rat were most numerous in the TL ganglia, with a smaller contribution in the LS ganglia. The vast majority of CTB‐positive neurons in both mouse and rat were positive for TRPV1 and CGRP and most likely unmyelinated, in that most colonic afferents were not positive for neurofilament heavy chain. In the mouse, the TL ganglia had a significantly higher percentage of TRPV1‐ and CGRP‐positive neurons than did the LS ganglia, whereas no differences were observed in the rat. The high incidence of TRPV1‐positive colonic afferents in rodents suggests that hypersensitivity from the viscera may be partially a TRPV1‐mediated event, thereby providing a suitable target for the treatment of visceral pain. J. Comp. Neurol. 494:246–259, 2006. © 2005 Wiley‐Liss, Inc.
From Pentalene to Dicyclopenta[b,g]naphthalene, or the Change towards Delocalized Structures
Authors: García Cuesta Inmaculada , Coriani Sonia , Lazzeretti Paolo , Sánchez de Merás Alfredo M. J. 
Published: November 2005

AbstractUsing triples‐corrected coupled‐cluster methods as well as other high‐level theoretical approximations, the optimized parameters and isomerization barriers of the family of compounds cyclopentadiene–(benzene)x–cyclopentadiene (x=0, 1, 2) are computed. In contrast to previous studies, s‐indacene presents a localized C2h geometry. Also, the localized structure of pentalene is found to be the most stable, but when two benzene rings are intercalated between the five‐member rings of pentalene, the resulting molecule preferably adopts a delocalized D2h conformation.
Flexible Synthetic Approach to a (S)‐Norcamphor‐Based Hydroperoxide: An Efficient Oxidant for Asymmetric Sulfoxidations
Authors: Lattanzi Alessandra , Piccirillo Sandro , Scettri Arrigo 
Published: November 2005

AbstractThe renewable tertiary (S)‐norcamphor‐based hydroperoxide 3 has been efficiently obtained by a simple 4‐step route. Remarkably, complete diastereocontrol was observed in the hydroperoxidation step. This oxidant, when used in the Ti‐catalyzed asymmetric sulfoxidation, showed to be as reactive as previously reported hydroperoxide 2, but more importantly, high chemoselectivity and improved asymmetric induction were achieved. The synthetic approach used offers the opportunity for designing a variety of functionalized and potentially more efficient norcamphor‐based hydroperoxides. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2006)
Relay Propagation of Crowding: The Trifluoromethyl Group as Both an Emitter and Transmitter of Steric Pressure
Authors: Schlosser Manfred , Cottet Fabrice , Heiss Christophe , Lefebvre Olivier , Marull Marc , Masson Eric , Scopelliti Rosario 
Published: November 2005

AbstractWhereas lithium 2,2,6,6‐tetramethylpiperidide (LITMP) abstracts a proton exclusively from the 4‐position of 3‐bromobenzotrifluoride, the same base attacks selectively the 2‐position when employed in the presence of N,N,N′,N′′,N′′‐pentamethyldiethylenetriamine and potassium tert‐butoxide (“Faigl mix”). 1‐Bromo‐3,5‐bis(trifluoromethyl)benzene also undergoes metalation at the 2‐position but [2‐bromo‐4‐(trifluoromethyl)phenyl]silane does not react at all, evidently locked up by a C–SiR3/C–Br buttressing effect. 2‐Bromo‐4‐(trifluoromethyl)pyridine, aza‐analogous to the parent model arene 3‐bromobenzotrifluoride, and both the benzo‐aza‐analogous 2‐bromo‐4‐(trifluoromethyl)quinoline and its regioinverted isomer 4‐bromo‐2‐(trifluoromethyl)quinoline are again readily deprotonated at the Br‐ and CF3‐flanked positions. However, the buttressing caused by the introduction of a methoxy group at the peri‐(5‐)position impedes the deprotonation of either bromo(trifluoromethyl)quinoline. Compared with methoxy, a peri‐methyl substituent (to be assimilated to an ortho‐tert‐butyl substituent) exerts a smaller buttressing effect. Although 4‐bromo‐5,7‐dimethoxy‐4‐(trifluoromethyl)quinoline proves to be again totally inert towards bases, 4‐bromo‐5,7‐dimethyl‐4‐(trifluoromethyl)quinoline can be lithiated at the 3‐position. Obviously, methoxy is more powerful as an emitter of steric pressure than methyl is and bromine is superior to trifluoromethyl as a transmitter of steric pressure. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2006)
Adjustment procedures to account for non‐ignorable missing data in environmental surveys
Authors: Munoz Breda , Lesser Virginia M. 
Published: November 2005

AbstractMethods for non‐response are well‐known techniques used in survey practice for handling missing data. In this approach, sampling units (respondents and non‐respondents) are classified in non‐response classes, and the sampling weight for each respondent unit is weighted by the inverse of an estimate of its response probability (also known as propensity score). Optimal weighting classes are selected using variables associated with the response but uncorrelated with the response indicator. We explore the assumptions needed to construct optimal adjustment classes in the case of non‐ignorable missing data in environmental surveys. We propose a modified Horvitz–Thompson non‐response estimator for the population total of the spatial random process of interest, and study some of its properties. By using the weighting class adjustment, we will account for the non‐ignorable missing data. Copyright © 2005 John Wiley & Sons, Ltd.
Uterine leiomyomata with deletions of Ip represent a distinct cytogenetic subgroup associated with unusual histologic features
Authors: Christacos Nicole C. , Quade Bradley J. , Cin Paola Dal , Morton Cynthia C. 
Published: November 2005

AbstractCytogenetic analysis of uterine leiomyomata (UL) shows that about 40% of these benign tumors have simple, clonal chromosomal rearrangements. In contrast, their presumed malignant counterpart, leiomyosarcomas (LMSs), typically has complex numerical and structural abnormalities. Several variants of benign uterine smooth‐muscle tumors are defined by histologic phenotypes intermediate between typical UL and LMS, and currently, little is known about their cytogenetic and molecular genetic features. From a subset of more than 800 karyotyped ULs, we identified a group of nine cases exhibiting near‐diploid karyotypes with loss of almost the entire short (p) arm of chromosome 1 [i.e., del(1)(p11p36)]. Loss of 1p was often associated with other aberrations, particularly loss of chromosomes 19 and/or 22. Of eight UL for which the histologic diagnosis was known, four were diagnosed as cellular UL; one displayed both hypercellularity and nuclear atypia. Loss of heterozygosity (LOH) analysis for chromosomal regions 1p36.23 and 1p21.1 demonstrated allelic loss for either a portion or the majority of 1p in 5 of 10 additional archival UL diagnosed with either cellular or atypical histology. RNA from two UL with loss of 1p was profiled using Affymetrix GeneChips, and those profiles were compared to our previously reported smooth‐muscle tumor expression profile. The transcriptional profiles of tumors with 1p deletion were more similar to those of leiomyosarcoma than to profiles of myometrium and UL, as determined by hierarchical cluster analysis. Comparison of the transcriptional profiles for UL with and without 1p− revealed 53 genes with differential regulation. Loss of 1p appears to define a subgroup of UL distinct from those previously recognized. Furthermore, 1p− appears to be associated with a specific histologic phenotype. The similarity between the transcriptional profiles of LMS and UL with 1p− suggests the possibility of a common pathogenetic mechanism. © 2005 Wiley‐Liss, Inc.