bluuebunny/crossref_metadata_2025_split huggingface dataset:
Progressive multifocal leukoencephalopathy associated with systemic lupus erythematosus: longitudinal observation of lymphocytes, JC virus in cerebrospinal fluid, and brain magnetic resonance imaging
Authors: Yamada Hidetada , Toko Megumi , Nakamori Masahiro , Ueno Hiroki , Aoki Shiro , Sugimoto Tomohiro , Yasutomi Hiroko , Nakamichi Kazuo , Maruyama Hirofumi 
Published: March 2024

AbstractProgressive multifocal leukoencephalopathy (PML) rarely occurs in patients with systemic lupus erythematosus (SLE). This report presents the case of a patient who developed PML due to SLE-associated multiple factors. A 60-year-old woman diagnosed with SLE undergoing multiple immunosuppressive therapies, including azathioprine, presented with cerebral cortical symptoms, lymphocytopenia, and vitamin B12 deficiency and was subsequently diagnosed with SLE-associated PML. We evaluated the cause and disease activity of PML, focusing on the longitudinal assessment of lymphocytopenia, JC virus (JCV) DNA copy number in the cerebrospinal fluid, and magnetic resonance imaging (MRI) findings. Discontinuing azathioprine and initiating alternative immunosuppressive treatments with intramuscular vitamin B12 injections affected lymphocytopenia and disease management. However, despite recovery from lymphopenia and JCV DNA copy number being low, the large hyperintense and punctate lesions observed on the fluid-attenuated inversion recovery (FLAIR) images exhibited varying behaviors, indicating that the balance between contributing factors for PML may have fluctuated after the initial treatment. Clinicians should be meticulous when assessing the underlying pathology of the multifactorial causes of PML due to SLE. The difference in the transition pattern of these lesions on FLAIR images may be one of the characteristics of MRI findings in PML associated with SLE, reflecting fluctuations in disease activity and the progression stage of PML.
Excess mortality in patients with non-functioning pituitary adenoma: a systematic review and meta-analysis
Authors: Bioletto F. , Sibilla M. , Gasco V. , Ghigo E. , Grottoli S. 
Published: March 2024

Abstract
Background
Patients with non-functioning pituitary adenoma (NFPA) often present with a variety of clinical manifestations and comorbidities, mainly determined by the local mass effect of the tumor and by hypopituitarism. Whether this has an impact on overall mortality, however, is still unclear.

Methods
PubMed/Medline, EMBASE, and Cochrane Library databases were systematically searched until May 2023 for studies reporting data either about standardized mortality ratios (SMRs) or about predictors of mortality in patients with NFPA. Effect sizes were pooled through a random-effect model. This systematic review and meta-analysis was registered in the International Prospective Register of Systematic Reviews (PROSPERO, #CRD42023417782).

Results
Eleven studies were eligible for inclusion in the systematic review; among these, five studies reported data on SMRs, with a total follow-up time of approximately 130,000 person-years. Patients with NFPA showed an increased mortality risk compared to the general population (SMR = 1.57 [95%CI: 1.20–1.99], p < 0.01). Age and sex appeared to act as effect modifiers, with a trend towards higher SMRs in females (SMR = 1.57 [95%CI: 0.91–2.41], p = 0.10) than in males (SMR = 1.00 [95%CI: 0.89–1.11], p = 0.97), and in patients diagnosed at age 40 years or younger (SMR = 3.19 [95%CI: 2.50–3.97], p < 0.01) compared to those with later onset of the disease (SMR = 1.26 [95%CI: 0.93–1.65], p = 0.13). The trend towards excess mortality was similar in patients with normal (SMR = 1.22 [95%CI: 0.94–1.53], p = 0.13) or deficient (SMR = 1.26 [95%CI: 0.82–1.79], p = 0.27) pituitary function.

Conclusions
Excess mortality is observed in patients with NFPA, regardless of pituitary function, especially in women and in patients with a younger age at diagnosis.
Education, educational mismatch and occupational status: an analysis using PIAAC data
Authors: Huertas Inés P. Murillo , Raymond José L. 
Published: March 2024

AbstractThe aim of this paper is to estimate the effect of longer schooling on the probability of entering a high-skill job and analyse whether the size of this effect depends on the (mis)match between the education attained by workers and the education required by the jobs. We use PIAAC data to estimate a multinomial logit model that predicts the odds of working in each occupational category and then simulate how these probabilities change for workers who have completed one more year of education, broken down by whether or not this additional year matches the educational requirements of the job. Our results suggest that, as observed from wages estimated according to an ORU equation, better education is positively associated with better jobs but the increased probability of getting a high-skill job as a result of completing one more year of education is greater for required than for mismatched education. The results differ notably by gender, with women being the ones who benefit most from an increase in education, especially in the absence of educational mismatch. These trends are observed whatever the institutional context, but we also found noteworthy differences by country.
Vom „rule of law revival“ zum „rule of law backsliding“: Ein Erklärungsversuch
Authors: von Steinsdorff Silvia 
Published: March 2024

ZusammenfassungGezielte Angriffe auf die rechtsstaatlichen Elemente konstitutioneller Demokratie sind ein zentraler Bestandteil des weltweit zu beobachtenden „democratic backsliding“. Teilweise lassen sie sich als Reaktion auf die mitunter unreflektierte, mechanistische Rechtsstaatsgläubigkeit der Demokratisierungsforschung und -politik der vergangenen 20 Jahre erklären. Allerdings missbrauchen autoritär-populistische Anti-Demokraten, die selbst in (noch) konsolidierten Demokratien gegenwärtig an Einfluss gewinnen, diese berechtigte Kritik, um ihre anti-pluralistischen Vorstellungen von einem angeblich homogenen Volkswillen und einer unumschränkten Mehrheitsherrschaft zu propagieren. Gegen diese Gefahren des „rule of law backsliding“ hilft nur eine klare Benennung des oft negierten Spannungsverhältnisses zwischen Rechtsstaat und Demokratie und die konstruktive Suche nach einer Balance zwischen beiden Prinzipien im Rahmen des demokratischen Verfassungsstaates.
The OPS-SAT case: A data-centric competition for onboard satellite image classification
Authors: Meoni Gabriele , Märtens Marcus , Derksen Dawa , See Kenneth , Lightheart Toby , Sécher Anthony , Martin Arnaud , Rijlaarsdam David , Fanizza Vincenzo , Izzo Dario 
Published: March 2024

AbstractWhile novel artificial intelligence and machine learning techniques are evolving and disrupting established terrestrial technologies at an unprecedented speed, their adaptation onboard satellites is seemingly lagging. A major hindrance in this regard is the need for high-quality annotated data for training such systems, which makes the development process of machine learning solutions costly, time-consuming, and inefficient. This paper presents “the OPS-SAT case”, a novel data-centric competition that seeks to address these challenges. The powerful computational capabilities of the European Space Agency’s OPS-SAT satellite are utilized to showcase the design of machine learning systems for space by using only the small amount of available labeled data, relying on the widely adopted and freely available open-source software. The generation of a suitable dataset, design and evaluation of a public data-centric competition, and results of an onboard experimental campaign by using the competition winners’ machine learning model directly on OPS-SAT are detailed. The results indicate that adoption of open standards and deployment of advanced data augmentation techniques can retrieve meaningful onboard results comparatively quickly, simplifying and expediting an otherwise prolonged development period.
Application of deep learning in iron ore sintering process: a review
Authors: Gong Yu-han , Wang Chong-hao , Li Jie , Mahyuddin Muhammad Nasiruddin , Seman Mohamad Tarmizi Abu 
Published: March 2024

AbstractIn the wake of the era of big data, the techniques of deep learning have become an essential research direction in the machine learning field and are beginning to be applied in the steel industry. The sintering process is an extremely complex industrial scene. As the main process of the blast furnace ironmaking industry, it has great economic value and environmental protection significance for iron and steel enterprises. It is also one of the fields where deep learning is still in the exploration stage. In order to explore the application prospects of deep learning techniques in iron ore sintering, a comprehensive summary and conclusion of deep learning models for intelligent sintering were presented after reviewing the sintering process and deep learning models in a large number of research literatures. Firstly, the mechanisms and characteristics of parameters in sintering processes were introduced and analysed in detail, and then, the development of iron ore sintering simulation techniques was introduced. Secondly, deep learning techniques were introduced, including commonly used models of deep learning and their applications. Thirdly, the current status of applications of various types of deep learning models in sintering processes was elaborated in detail from the aspects of prediction, controlling, and optimisation of key parameters. Generally speaking, deep learning models that could be more effectively implemented in more situations of the sintering and even steel industry chain will promote the intelligent development of the metallurgical industry.
Exploring Potential Referral Pathways for Renal Artery Denervation and Developing a Centre of Excellence in Ireland
Authors: Leahy Niall , Wagener Max , Shahzad Shirjeel , Murphy Darragh , McMorrow Amy , Coen Eileen , Sharif Ruth , Sharif Faisal 
Published: March 2024

Abstract
Arterial hypertension is one of the most significant and prevalent risk factors for cardiovascular disease. Despite widespread awareness of the condition, as well as a multitude of available antihypertensive drug classes, rates of uncontrolled hypertension remain high on a global scale. Frequently, poor compliance with anti-hypertensive medication plays a big role in patients’ inability to attain adequate blood pressure control. In individuals with resistant and/or uncontrolled hypertension, renal denervation is an emerging device-based therapy that has shown to be efficacious and safe in reducing blood pressure in several sham controlled trials. Additionally, it represents a treatment option for patients intolerant to oral pharmacotherapy.
University Hospital Galway has been performing renal denervation procedures over the past number of years within multicentre, international sham-controlled trials and registries. Representing a novel and emerging antihypertensive treatment option, sources of referral for renal denervation are diverse and multiple; thus, there is an unmet need for standardised referral structures in Ireland. Herein, we review current and developing referral pathways for renal denervation at our institution, and discuss streamlined patient management and requirements to establish a centre of excellence.
Utilizing ensemble learning in the classifications of ductile and brittle failure modes of UHPC strengthened RC members
Authors: Taffese Woubishet Zewdu , Zhu Yanping , Chen Genda 
Published: March 2024

AbstractThis study aims to achieve the swift and precise classification of ductile and brittle failure modes in flexural reinforced concrete (RC) members, specifically those with tension sides strengthened by ultrahigh performance concrete (UHPC). Employing six ensemble learning techniques—Bagging, Random Forest, AdaBoost, Gradient Boosting, XGBoost, and LightGBM—the authors utilize a comprehensive dataset comprising 14 features, which include manually labeled failure modes obtain from load–deflection curves. The model training spans four scenarios, varying in the inclusion or exclusion of features describing the cross-sectional area of RC members and moment resistance. XGBoost emerges as the most effective classifier, achieving an impressive 84% accuracy with high confidence. Additionally, the study employs the Shapley Additive Explanation (SHAP) technique on the best-performing model to illuminate the significance and impacts of various features in UHPC-strengthened flexural members’ failure modes. Notably, moment resistance and UHPC tensile strength surface as the most influential factors in predicting failure modes. Increased rebar yield strength, UHPC compressive strength, UHPC reinforcement ratio, and steel fiber volume in UHPC contribute to enhanced ductility in flexural members, while heightened moment resistance and UHPC layer thickness, along with a robust RC-UHPC interface, tend to induce brittleness. The introduction of such an effective failure modes classification model, coupled with the model’s explainability, instills trust in its predictions and facilitates seamless integration into real-world applications, particularly in seismic areas. The model’s ability to operate without the need for pre-experimental tests marks a significant advancement in the field.
Rethinking Church–State Relations in Seventeenth-Century Philippines: The Guerrero-Hurtado de Corcuera and Pardo-Audiencia Controversies
Authors: Coello de la Rosa Alexandre 
Published: March 2024

AbstractThe early modern Philippine archipelago is often described as being under the power of a frailocracy with a far-reaching impact. From a microhistorical approach of ecclesiastical contentiousness, I argue that the intermittent clashes between and inside the two pillars of colonial rule—the civil and ecclesiastical powers—belie the church's overarching control over state affairs. The church was not a monolithic unit in the Philippines, but was rather highly fragmented, especially in distant Asian enclaves, and it was not independent, but relied on royal patronage, diplomacy, and transnational networks. Using archival materials, official reports, religious manifestos, and royal appointments and decrees, I focus upon two significant case studies of the two exiled archbishops of Manila, Fray Hernando Guerrero, OSA, and Felipe Pardo, OP, to explore factionalism, negotiation, and microlevel political constellations as a way to approach conflicting church–state relations in seventeenth-century Philippines from a more nuanced perspective.
Potential contribution of agronomic practices and conservation agriculture towards narrowing smallholders’ yield gaps in Southern Africa: lessons from the field
Authors: Nyagumbo Isaiah , Nyamayevu Donald , Chipindu Lovemore , Siyeni Donald , Dias Domingos , Silva João Vasco 
Published: March 2024

Summary
Smallholders in Southern Africa continue to grapple with low maize productivity despite this being the staple food crop. This study sought to analyze and isolate the relative contribution of agronomic practices to maize yields obtained by smallholders in Malawi and Mozambique using data generated from on-farm trials testing the performance of conservation agriculture cropping systems. The trials were implemented in two communities, namely Kasungu district in Malawi and Sussundenga district in Mozambique, and ran for seven consecutive growing seasons starting in 2010–2011. Maize yield was measured annually in the on-farm trials, which included a ‘control treatment’ representing an improved farm practice, and in neighboring fields managed by the same farmers on their own, hence representing a ‘true farm practice’. Results indicated that maize yield increased linearly with increasing plant population at harvest at both sites. On average, an increase in plant population at harvest by 1000 plants ha–1 resulted in an increase in maize yield of 90 and 63 kg ha–1 at Kasungu and Sussundenga, respectively. The greatest maize yields were obtained when plant population at harvest exceeded 40 000 plants ha–1. Yet, the plant population at harvest was below the generally recommended optimum for most of the cropping systems studied and in most growing seasons. Furthermore, the use of agronomic practices alone without conservation agriculture (i.e., improved varieties, fertilizer management, and timely weed control) resulted in maize yield gains of as much as 54% and 43% relative to the ‘true farm practice’ at Kasungu and Sussundenga, respectively. Overall, the proportion of these yield increases relative to the ‘true farm practice’ accounted for by agronomic practices amounted to 53–70% and 57–85% at Kasungu and Sussundenga for the highest to the lowest-yielding cropping system. Although conservation agriculture significantly improved maize yield at both sites, such increases were smaller in magnitude compared to the yield gains derived from improved agronomic practices. The study suggests that considerable strides toward narrowing maize yield gaps in Southern Africa can be achieved through improvement of current crop management practices, let alone adhering to the conservation agriculture principles of minimum tillage, residue retention, and crop diversification.
Collisional rate coefficients for astrophysics
Authors: Faure Alexandre 
Published: March 2024

AbstractIn the interstellar medium, inelastic collisions are so rare that they cannot maintain a local thermodynamical equilibrium (LTE). Atomic and molecular populations therefore do not follow a simple Boltzmann distribution and non-LTE spectra are the rule rather than the exception. In such conditions, accurate state-to-state collisional data are crucial for a quantitative interpretation of spectra. In recent years, considerable progress has been made in quantum calculations of inelastic cross sections for a variety of targets, types of transitions and projectiles. For a few benchmark species, detailed comparisons between theory and experiment were also carried out at the state-to-state level and in the quantum regime. In this article, we highlight such comparisons for three important molecules: CO, H2O and CH+. We also describe current computational efforts to extend these advances to ever larger targets, new transition types, and new environments (e.g. stellar envelopes or cometary atmospheres).
Contribution of small telescopes at the Oukaïmden observatory in Morocco to study atmospheric dynamics and shocks waves in variables stars RR Lyr and R Scuti
Authors: Benhida A. , Sefyani F. L. , Chafouai K. , El Jariri Y. , Chouqar J. , Benkhaldoun Z. , Kolenberg K. , Sylla S. 
Published: March 2024

AbstractThrough Spectroscopy, we aim to develop the field of pulsating stars, especially the atmospheric dynamics of high amplitude pulsators such as RR Lyr and R Scuti, in order to establish new models of the mechanical and thermal behavior of their atmospheres (shock waves, relaxation time, energy loss…). We used high-resolution spectra over a total of 81 nights from made with the spectrograph Eshell during years 2013 and 2015 runs from Oukaïmeden observatory in the High Atlas mountains (Morocco) completed with made with the spectrograph ELODIE (Haute Provence observatory, France) during years 1994–1997. A detailed analysis of line profile variations over the whole pulsation cycle is performed. Shock wave velocity and lines intensity were used as indicators of atmospheric dynamics activities. We have obtained and compared our results with those obtained by the large telescopes, we have obtained thanks to our site very satisfactory results, Indeed : For RR lyr: For the first time the second apparition of Helium (D3) was detected using our Telescope (0.35m) at Oukaïmeden Observatory.For the first time, during the phase of expansion of the star, the emission of the line D3 is visible on various phases Blazhko, including during the minimum of the cycle Blazhko.Also, we presented the results of a long- term, high-resolution spectroscopic study of the variable star R Sct. We analyzed the features of the optical spectra of this object and found RSct shows irregular behavior in its slight variations for much of the time that it was observed. Its average period is close to 142 d, but some- times the irregularities are so strong that it is not possible to define a periodic variation.
Charlotte Emma Moore Sitterly: She “turned chaos into order”
Authors: DeVorkin David H. 
Published: March 2024

AbstractAt the 1988 IAU General Assembly in Baltimore, among many who offered reminiscences of earlier meetings was Charlotte Moore Sitterly. She first attended the 1932 GA meeting, in Cambridge, Mass., though she already “helped to assemble material for delegates” since the 1920s, for astronomers at Princeton, Mount Wilson and Lick Observatory. She was an ardent member of the new Commission 14 (then called “Fundamental Spectroscopic Data”), eventually becoming its president. In her 1988 reminiscence, she recalled that the Commission meeting was sparsely attended and very informal, but astronomers’ “never-ending demand for tables and data analysis” soon changed all that (Sitterly 1988). Here we provide a brief overview of how Charlotte Moore Sitterly came to be at the very center of that change, which Donald Menzel early on described as having “turned chaos into order” and just a “little short of miraculous” (Menzel 1928) We will recount highlights of her early life, aspirations, training, and contributions during her years at Princeton, Berkeley, Mount Wilson, and the National Bureau of Standards.
Deep Fault‐Controlled Fluid Flow Driving Shallow Stratigraphically Constrained Gas Hydrate Formation: Urutī Basin, Hikurangi Margin, New Zealand
Authors: Gorman Andrew R. , Crutchley Gareth J. , Baker Dylan R. , Fraser Douglas R. A. , Henrys Stuart A. , Tréhu Anne M. , Harris Robert N. , Phrampus Benjamin J. , Pecher Ingo A. 
Published: March 2024

AbstractThe Hikurangi Margin east of New Zealand's North Island hosts an extensive gas hydrate province with numerous gas hydrate accumulations related to the faulted structure of the accretionary wedge. One such hydrate feature occurs in a small perched upper‐slope basin known as Urutī Basin. We investigated this hydrate accumulation by combining a long‐offset seismic line (10‐km‐long receiver array) with a grid of high‐resolution seismic lines acquired with a 600‐m‐long hydrophone streamer. The long‐offset data enable quantitative velocity analysis, while the high‐resolution data constrain the three‐dimensional geometry of the hydrate accumulation. The sediments in Urutī Basin dip landward due to ongoing deformation of the accretionary wedge. These strata are clearly imaged in seismic data where they cross a distinct bottom simulating reflection (BSR) that dips counterintuitively in the opposite direction to the regional dip of the seafloor. BSR‐derived heat flow estimates reveal a distinct heat flow anomaly that coincides spatially with the upper extent of a landward‐verging thrust fault. We present a conceptual model of this gas hydrate system that highlights the roles of fault‐controlled fluid flow at depth merging into strata‐controlled fluid flow into the hydrate stability zone. The result is a layer‐constrained accumulation of concentrated gas hydrate in the dipping strata. Our study provides new insight into the interplay between deep faulting, fluid flow and gas hydrate formation within an active accretionary margin.