bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effect of comprehensive nursing on the quality of life and swallowing function in individuals diagnosed with ischemic stroke
Authors: Hu Heng-Fen , Sang Yu-Fei , Xiao Yan-Qing 
Published: March 2024

BACKGROUND
Ischemic stroke (IS) is a widely recognized disease characterized by high prevalence, mortality, morbidity, disability, and recurrence rates. It ranks prominently in terms of mortality, constituting 60%-80% of stroke cases.
AIM
To explore the impact of comprehensive nursing care on the quality of life and swallowing function in individuals diagnosed with IS.
METHODS
This study comprised 172 patients with IS admitted to our hospital between February 2018 to March 2021. The participants were divided into two groups, namely the control group (n = 80) receiving routine care and the research group (n = 92) receiving comprehensive care. Various assessment scales, including the standard swallowing function assessment scale (SSA), National Institutes of Health Stroke scale (NIHSS), European stroke scale (ESS), self-rating anxiety scale (SAS), self-rating depression scale (SDS), Barthel index (BI), and the motor function assessment scale (MAS), were employed to evaluate the improvement in swallowing function, neurological deficits, clinical outcomes, anxiety, depression, daily living activities, and motor function before and after care. Furthermore, the study compared the occurrence of adverse reactions during the nursing period, life quality before and after the intervention, rehabilitation compliance, and nursing satisfaction between the two groups.
RESULTS
After the nursing intervention, the research group exhibited significantly improved SSA and NIHSS scores compared to the control group (P < 0.05). Moreover, both groups demonstrated significant reductions in SAS and SDS scores (P < 0.05), with the research group showing more obvious advantages (P < 0.05). Compared to the control group, the research group displayed significantly better ESS, BI, and MAS scores (P < 0.05), coupled with a lower incidence of adverse reactions (P < 0.05). Additionally, the research group demonstrated markedly higher levels of life quality, rehabilitation compliance, and nursing satisfaction compared to the control group (P < 0.05).
CONCLUSION
Comprehensive nursing effectively improved swallowing function, quality of life, and patient satisfaction, highlighting its clinical significance.
Appendiceal intussusception complicated by adenocarcinoma of the cecum: A case report
Authors: Long Yu , Xiang Yi-Ning , Huang Fei , Xu Lei , Li Xiao-Yun , Zhen Yun-Huan 
Published: March 2024

BACKGROUND
Appendiceal intussusception is a pathological condition in which the appendix is inverted into the cecum, which may cause symptoms that resemble those of other gastrointestinal disorders and may induce intestinal obstruction. The rarity of this case presentation is the co-occurrence of appendiceal intussusception and cecal adenocarcinoma, a combination that to our knowledge has not previously been reported in the medical literature. This case provides new insights into the complexities of diagnosing and managing overlapping pathologies.
CASE SUMMARY
A 25-year-old woman presented with persistent periumbilical pain and bloody stools. An initial biopsy showed cecal cancer; however, subsequent colonoscopy and computed tomography findings raised the suspicion of appendiceal intussusception, which was later confirmed postoperatively. This unique case was characterized by a combination of intussusception and adenocarcinoma of the cecum. The intervention included a laparoscopic right hemicolectomy, which led to the histopathological diagnosis of mucinous adenocarcinoma with appendiceal intussusception. The patient recovered well postoperatively and was advised to initiate adjuvant chemotherapy. This case highlights not only the importance of considering appendiceal intussusception in the differential diagnosis, but also the possibility of appendicitis and the atypical presentation of neoplastic lesions.
CONCLUSIONS
Physicians should consider the possibility of appendiceal intussusception in cases of atypical appendicitis, particularly when associated with neoplastic presentation.
Multilocular thymic cysts can be easily misdiagnosed as malignant tumor on computer tomography: A case report
Authors: Sun Jun , Yang Qing-Ning , Guo Yi , Zeng Ping , Ma Long-Yan , Kong Ling-Wen , Zhao Bo-Ying , Li Chuan-Ming 
Published: March 2024

BACKGROUND
Multilocular thymic cyst (MTC) is a rare mediastinal lesion which is considered to occur in the process of acquired inflammation. It is usually characterized by well-defined cystic density and is filled with transparent liquid.
CASE SUMMARY
We report on a 39-year-old male with a cystic-solid mass in the anterior mediastinum. Computer tomography (CT) imaging showed that the mass was irregular with unclear boundaries. After injection of contrast agent, there was a slight enhancement of stripes and nodules. According to CT findings, it was diagnosed as thymic cancer.
CONCLUSION
After surgery, MTC accompanied by bleeding and infection was confirmed by pathological examination. The main lesson of this case was that malignant thymic tumor and MTC of the anterior mediastinum sometimes exhibit similar CT findings. Caution is necessary in clinical work to avoid misdiagnosis.
Analysis and monitoring of drug therapy in a patient with peptic ulcer complicated by infection: A case report
Authors: Gou Yan-Ping , Huang Yue , Chen Li , Zheng Wei , Zheng Yun-Hua 
Published: March 2024

BACKGROUND
The role of primary-level medical pharmacists in medical institutions in China is limited; therefore, it is necessary to explore the role of pharmacists in the process of drug treatment.
CASE SUMMARY
A Chinese pharmacist participated in the complete treatment of a patient with a duodenal ulcer. The rationale for drug treatment was evaluated, and adjustments were made to the antacid and anti-infective regimen, as well as the dose and frequency of administration. Body temperature, routine blood examination, and adverse drug reactions were strictly monitored. During treatment, the pharmacist recommended anti-infective therapy with ampicillin–sulbactam, which effectively controlled the infection. Additionally, the pharmacist suggested changing famotidine to lansoprazole for acid suppression and gastroprotective treatment, combined with Chinese patent medicine such as Kangfuxin Liquid. This is the first case report of a pharmacist in primary-level medical institutions adjusting drug use for patients with duodenal ulcer and pulmonary infection.
CONCLUSION
A pharmacist participated in the treatment process, provided individualized medication adjustment, and achieved good clinical results.
Effect of a mother-baby delivery pack on institutional deliveries: A community intervention trial to address maternal mortality in rural Zambia
Authors: Mukonka Victor , Sialubanje Cephas , McAuliffe Fionnuala M. , Babaniyi Olusegun , Malumo Sarai , Phiri Joseph , Fitzpatrick Patricia 
Published: March 2024

Objectives
To test the effect of providing additional health education during antenatal care (ANC) and a mother-baby delivery pack on institutional deliveries in Monze, Zambia.

Setting
16 primary health facilities conducting deliveries in the district.

Participant
A total of 5000 pregnant women at any gestation and age attending antenatal care (ANC) services in selected health facilities were eligible for enrolment into the study. Out of these, 4,500 (90%) were enrolled into and completed the study. A total of 3,882 (77.6%) were included in the analysis; 12.4% were not included in the analysis due to incomplete data.

Intervention
A three-year study (2012 to 2014) analysing baseline delivery data for 2012 and 2013 followed by a community intervention trial was conducted from January to December 2014. Health facilities on the western side were assigned to the intervention arm; those on the eastern side were in the control. In addition to the health education provided during routine ANC visits, participants in the intervention arm received health education and a mother-baby delivery pack when they arrived at the health facility for delivery. Participants in the control arm continued with routine ANC services.

Outcome measures
The primary measure was the number of institutional deliveries in both arms over the one-year period. Secondary measures were utilisation of ANC, post-natal care (PNC) and under-five clinic services. Descriptive statistics (frequencies, proportions, means and standard deviation) were computed to summarise participant characteristics. Chi-square and Independent T-tests were used to make comparisons between the two arms. One way analysis of variance (ANOVA) was used to test the effect of the intervention after one year (p-value<0.05). Analysis was conducted using R-studio statistical software version 4.2.1. The p-value<0.05 was considered significant.

Results
Analysis showed a 15.9% increase in the number of institutional deliveries and a significant difference in the mean number of deliveries between intervention and control arms after one year (F(1,46) = 18.85, p<0.001). Post hoc analysis showed a significant difference in the mean number of deliveries between the intervention and control arms for 2014 (p<0.001). Compared to the control arm, participants in the intervention arm returned earlier for PNC clinic visit, brought their children back and started the under-five clinic visits earlier.

Conclusion
These findings provide evidence for the effectiveness of the mother-baby delivery pack and additional health education sessions on increasing institutional deliveries, PNC and under-five children’s clinic utilisation in rural Zambia.

Trial registration
ISRCTN Registry (ISRCTN15439813 DOI 10.1186/ISRCTN15439813); Pan African Clinical Trial Registry (PACTR202212611709509).
Unraveling athletic performance: Transcriptomics and external load monitoring in handball competition
Authors: Ezquerra Condeminas Pol , Mallol Milos , Font Roger , Tremps Victor , Gutiérrez Jose Antonio , Rodas Gil , Perera Lluna Alexandre , Soria José Manuel 
Published: March 2024

Objective
This study aims to comprehend the impact of handball practice on sub-elite athletes by investigating transcriptomic changes that occur during a match. The primary focus encompasses a dual objective: firstly, to identify and characterize these transcriptomic alterations, and secondly, to establish correlations between internal factors (gene expression), and external loads measured through Electronic Performance and Tracking Systems (EPTS variables). Ultimately, this comprehensive analysis seeks to evaluate both acute and chronic responses to exercise within the context of handball training.

Methods
The study included sixteen elite male athletes from the FC Barcelona handball second team. Blood samples were extracted at three different time points: before the match at baseline levels (T1), immediately upon completion (T2), and 24 hours after completion (T3). Differential gene expression, Gene Ontology Term and Kyoto Encyclopedia of Genes and Genomes pathway enrichment analyses were conducted in two comparisons: Comparison 1 (T1 vs T2) and Comparison 2 (T1 vs T3). Further, the correlation between gene expression levels and training variables (external load) was conducted.

Results
In T1 vs T2, 3717 of the 14632 genes detected were differentially expressed (adjusted p-value < 0.05), and enrichment of terms related to the immune system, mitochondria, and metabolic processes was found. Further, significant linear correlations were obtained between High-Speed running (HSR) and high-intensity variables such as acceleration ACC and deceleration DEC values with amino acids, and inflammatory and oxidative environment-related pathways, both in chronic and acute response.

Conclusions
This research highlights the effects of external workload on elite athletes during a handball match and throughout the season. The study identifies deregulation in the immune system, mitochondrial functions, and various metabolic pathways during the match. Additionally, it establishes correlations between the external load and pathways associated with amino acids, inflammation, oxidative environment, and regulation. These findings offer insights into the immediate and chronic responses of athletes to physical effort.
Burkitt lymphoma: The effect of age, sex and delay to diagnosis on treatment completion and outcome of treatment in 934 Patients in Cameroon
Authors: Hesseling Peter Bernard , Afungchwi Glenn Mbah , Njodzeka Bernard Wirndzem , Wharin Paul , Kouya Francine Nicole , Kruger Mariana 
Published: March 2024

Introduction
The role of age and sex in the presentation and outcome of endemic Burkitt lymphoma (BL) has not been studied recently. This study analysed these factors in 934 patients with BL who had received cyclophosphamide and intrathecal methotrexate as treatment.

Methods
Records of 934 children diagnosed with BL from 2004 to 2015 were obtained from our Paediatric Oncology Networked Database (POND) cancer registry. Age at diagnosis, sex, disease stage, time to diagnosis, delay in diagnosis, completion of treatment, rate of abandonment, and one-year survival rates were recorded and statistically analysed.

Results
The male to female ratio of 1.41 for the study population of 934. The median delay from onset of symptoms to diagnosis was 31 days. The St Jude stage distribution was I = 6.4%, II = 5.9%, III = 71.5% and IV = 16.2%. Significantly more patients presented with stage III disease in age groups 5–9 and 10–14 years than 0–4 years. The overall 1-year survival rate was 53.45%, respectively 77.1% for stage I, 67.9% for stage II, 55.1% for stage III and 32.4% for stage IV disease (p<0.001). There was no significant difference in survival by sex and age group.

Conclusion
Patients aged under 5 years presented with less-advanced disease, but survival was not affected by age. Sex did not influence delay to diagnosis and overall survival. The long delay between the onset of symptoms and diagnosis emphasises the need for interventions to achieve an earlier diagnosis and a better survival rate.
Feasibility of a family-oriented mHealth intervention for Chinese Americans with type 2 diabetes: A pilot randomized control trial
Authors: Hu Lu , Shi Yun , Wylie-Rosett Judith , Sevick Mary Ann , Xu Xinyi , Lieu Ricki , Wang Chan , Li Huilin , Bao Han , Jiang Yulin , Zhu Ziqiang , Yeh Ming-Chin , Islam Nadia 
Published: March 2024

Objectives
To test the feasibility, acceptability, and potential efficacy of a mHealth intervention tailored for Chinese immigrant families with type 2 diabetes (T2D).

Methods
We conducted a pilot randomized controlled trial (RCT) with baseline, 3-, and 6-month measurements. Participating dyads, T2D patients and families/friends from NYC, were randomized into the intervention group (n = 11) or the wait-list control group (n = 12). Intervention includes 24 videos covering T2D self-management, behavioral techniques, and family-oriented sessions. Feasibility and acceptability were measured respectively by the retention rate and video watch rate, and a satisfaction survey. Patients’ HbA1c, weight, and self-management were also assessed to test potential efficacy.

Results
Most T2D patients (n = 23; mean age 56.2±9.4 years; 52.2% male) and families/friends (n = 23, mean age 54.6±11.2 years; 52.2% female) had high school education or less (69.6% and 69.6%), annual household income < $25,000 (65.2% and 52.2%), and limited English proficiency (95.7% and 95.7%). The retention rates were not significantly different between the intervention and the control groups for both the patients (90.91% vs 83.3%, p = 0.589); and their families/friends (3-month: 90.9% vs 75%, p = 0.313; 6-month: 90.9% vs 83.3%, p = 0.589). The mean video watch rate was 76.8% (7%). T2D patients and families/friends rated satisfaction as 9.4 and 10 out of 10, respectively. Despite no between-group differences, the intervention group had significantly lower HbA1c (p = 0.014) and better self-management (p = 0.009), and lost 12 lbs. on average at 6 months (p = 0.079), compared to their baseline levels.

Conclusions
A culturally-tailored, family-based mHealth intervention is feasible and acceptable among low-income, limited English-proficient Chinese families with T2D in NYC. Significant changes in HbA1c and self-management within the intervention group indicate this intervention may have potential efficacy. Given the small sample size of this study, a future RCT with adequate power is needed to test efficacy.
Characteristics and clinical outcomes of patients with kidney failure of unknown aetiology from ANZDATA registry
Authors: Wang Lucy S. , Vangaveti Venkat , Ng Monica S. Y. , Mallett Andrew J. 
Published: March 2024

Introduction
Kidney failure of unknown aetiology (uESKD) is also heavily location dependent varying between 27% in Egypt to 54% in Aguacalientes, Mexico. There is limited information about the characteristics of people with uESKD in Australia and New Zealand, as well as their clinical outcomes on kidney replacement therapy.

Methods
Data on people commencing kidney replacement therapy 1989–2021 were received from the Australia and New Zealand Dialysis and Transplant (ANZDATA) registry. Primary exposure was cause of kidney failure–uESKD or non-uESKD (known-ESKD). Primary outcome was mortality. Secondary outcome was kidney transplantation. Dialysis and transplant cohorts were analysed separately. Cox Proportional Hazards Regression models were used to evaluate correlations between cause of kidney failure and mortality risk. Subgroup analyses were completed to compare mortality risk in people with uESKD to those with diabetic nephropathy, autosomal dominant polycystic kidney disease (ADPKD), glomerular disease and other kidney diseases.

Results
This study included 60,448 people on dialysis and 20,859 transplant recipients. 1-year, 3-year and 5-year mortality rates in people with uESKD on dialysis were 31.6%, 58.7% and 77.2%, respectively. 1-year, 3-year and 5-year mortality rates in transplant recipients with uESKD were 2.8%, 13.8% and 24.0%, respectively. People with uESKD on dialysis had a higher mortality risk compared to those without uESKD on univariable and multivariable analyses (adjusted hazard ratio [AHR] 1.10, 95% CI 1.06–1.16, p<0.001). Transplant recipients with uESKD have a higher mortality risk compared to those without uESKD on univariable and multivariable analyses (AHR 1.17, 95% CI 1.01–1.35, p<0.05). People with uESKD had similar likelihood of kidney transplantation compared to people with known-ESKD.

Conclusion
People with uESKD on kidney replacement therapy have higher mortality risk compared to people with other kidney diseases. Further studies are required to identify contributing factors to these findings.
EDUCAÇÃO INCLUSIVA E A RELAÇÃO FAMÍLIA-ESCOLA
Authors: Da Silva Tomé Adonis , Carneiro Martins Ida , Gimenez Roberto 
Published: March 2024

O presente artigo tem por objetivo comparar quantitativamente duas décadas de produções científicas sobre a relação família-escola, na educação inclusiva, e analisar qualitativamente os desdobramentos das temáticas dessas produções, com foco no segundo decanato. Este estudo comparativo fundamentou-se na busca sistemática em bancos de dissertações e teses, e utilizou-se metodologicamente de enfoque fenomenológico, obtendo unidades significativas das produções. O trabalho está organizado em duas etapas: 1) comparação quantitativa de duas décadas (2001-2011; 2012-2022); e 2) descrição e análise da unidade significativa de maior frequência da segunda década. O foco na percepção, da família, educadores e demais agentes, deve-se ao fato de uma mudança metodológica, de público-alvo e de contexto sócio-político, cuja finalidade é incentivar mais o processo inclusivo na educação. Nesse sentido, concluiu-se admitindo que existe implicitamente na constituição da relação família-escola, na educação inclusiva, o preconceito como atitude em ambas polaridades dessa relação, suscitando uma discussão ética e política.
PALAVRAS-CHAVE: relação família-escola. educação inclusiva. preconceito.
Endeudamiento público municipal en México en el periodo 2009-2021: los efectos de las reformas legales y la pandemia por covid-19
Authors: Huerta Cuervo Rocío 
Published: March 2024

Este artículo explica la condición de endeudamiento público de los municipios de México de 2009 a 2021, identificando de manera específica el impacto de las reformas legales de 2015 y del periodo pandémico 2020-2021. Este estudio toma como base la información del Instituto Nacional de Estadística y Geografía (Inegi) sobre finanzas públicas municipales y de la Ciudad de México. Es un estudio cuantitativo que empleó los programas Excel y Stata para obtener los indicadores de vulnerabilidad y sostenibilidad de la deuda municipal, así como un modelo de mínimos cuadrados ordinarios para identificar las correlaciones entre las principales variables. De 2009 a 2021 hubo un aumento del endeudamiento promedio anual municipal de 11,8% (B:2013). Las reformas de 2015 no evitaron el sobreendeudamiento posterior. En los indicadores de deuda se presentan resultados diferenciados entre el indicador de vulnerabilidad y los indicadores de sostenibilidad. El contexto institucional favorece la superación de techos de endeudamiento y ello debe ser considerado por los legisladores.
Este estudio toma como base la información del INEGI sobre finanzas públicas municipales y de la Ciudad de México. Es un estudio cuantitativo que empleó el software de INFOSTAT para obtener los indicadores de vulnerabilidad y sostenibilidad de la deuda municipal, así como ejercicios de regresión lineal en torno a las variables de finanzas públicas.
De 2009 a 2021 hubo un aumento del endeudamiento promedio anual municipal de 11.8% (B:2013). Las reformas de 2015 no evitaron el sobreendeudamiento posterior. En los indicadores de deuda se presentan resultados diferenciados entre el indicador de vulnerabilidad y los indicadores de sostenibilidad. El contexto institucional favorece la superación de techos de endeudamiento y ello debe ser considerado por los legisladores.
The Optimal Tax Structure from GDP-growth Perspective
Authors: Kutasi Gábor , Marton Ádám 
Published: March 2024

The tax multiplier in macroeconomics assumes a negative relationship between the volume of tax revenue in a country and its GDP. However, it may also be relevant to GDP growth whether the same volume of tax burden is levied in a different structure. Can the fiscal government stimulate the GDP growth by restructuring the tax revenues? The following study analyses the linkage between GDP growth rate and the structure of tax revenues. A database contains data from 25 EU countries which are open economies in the European single market. The period starts in 1996 and lasts until 2018. The Eurostat classification is used for tax types. Dynamic GMM tests are applied for GDP equations based on expenditure and output approach and extended with taxation category determinants. The conclusions are that tax structure based on consumer taxes on production and income tax can support the economic growth, meanwhile higher weight of social contribution is a destructive factor for income expansion. The policy recommendation is to reweight the tax structure toward indirect taxes from direct taxes if economic growth is a preference in the tax system in a trade-oriented open economy. Novelty of the research: Application of Arellano-Bond version of Dynamic GMM test, comparable results for Solow-Swan and augmented Cobb-Douglas approaches, the composition of database, the falsification and verification of statements of the existing literature.