bluuebunny/crossref_metadata_2025_split huggingface dataset:
Hierarchical classification of entrepreneurial risks
Authors: Yulgushev A. M. 
Published: April 2024

Aim. Improvement of the hierarchical classification of entrepreneurial risks.Objectives. Justification of the relevance of modernization of the hierarchical classification of entrepreneurial risks, coverage of this problem and the experience of its solution in the scientific community; selection of the most acceptable classification of entrepreneurial risks and search for its weaknesses; introduction of new classes and determination of their place in the hierarchical classification of entrepreneurial risks; addition of existing classes of entrepreneurial risks; visualization of cause-and-effect relations between the elements of the hierarchical classification of entrepreneurial risks; argumentation of the following aspects of the hierarchical classification of entrepreneurial risks.Methods. The author applied the system approach, methods of logical analysis, synthesis, induction and deduction, as well as situational modeling and classification.Results. On the basis of the known researches the hierarchical structure, interconnected system of entrepreneurial risks is selected and supplemented. The class “Economic risks” was supplemented: the place and interrelations of transportation risks in the classification of the upper level were established. The class “Personnel risks” has been expanded: the place and interrelations of risks of reduction of personnel potential of the company have been determined. The scheme of influence of factor risks on decrease of personnel potential of the company is developed, and also causal relations are grounded. The architecture of the “Financial Risks” class is enriched with six risks. They include interest and credit risks, settlement risk, risk of solvency loss, risk of lost profit, risk of non-payment on commercial transactions and risk of loss of competitiveness. A new class in the system classification of top-level entrepreneurial risks “Digital Risks” is supplemented and described. The structural definitions are singled out, the place and interrelations of the proposed class are determined. The author proposed the place of the risk of reduction of innovation potential outside the classes, opening the prospect of considering a new class of the upper level.Conclusions. Risk management should have a regular and systematic character. Classification as an element of entrepreneurial risk management requires updating and modernization in connection with new challenges in the business environment. The article substantiates the scientific and practical significance of the outlined approach.
Overview of Brown-Sequard Syndrome.
Authors: Sharon Evelyn , Keerthanashree RNP 
Published: April 2024

A neurologic syndrome called Brown-Séquard syndrome is brought on by spinal cord hemisection. On the side of the body, ipsilateral to the lesion, it presents as weakness or paralysis, proprioceptive abnormalities, and loss of pain and temperature perception. Brown-Séquard syndrome is an incomplete spinal cord syndrome with a range of severity in its clinical presentation.
One of the most intricate and fascinating areas of the nervous system to study is the spinal cord. Its overwhelming clinical presentation, development problems, lesions, and intricate connections call for a deeper comprehension of its anatomical and physiological makeup.
Like the brain, the extremely fragile and sensitive spinal cord is well-protected by the robust bony cage comprising the vertebral arch and vertebral bodies. Together, they create the spinal hollow, or long spinal column, which houses the spinal cord. Millions of neurons reside in the spinal cord, and their bundled fibers run as ascending or descending tracts. Thirty-one pairs of spinal nerves, primarily supplying the trunk and limbs, emerge from the spinal cord. These are mixed spinal nerves with a motor component that assists in controlling the trunk and voluntary muscles in all limbs. Additionally, they have a sensory component that aids in taking in the sensory data from these regions. Therefore, for a better understanding of the clinical presentation and its pathology in any spinal cord lesion, it is imperative to grasp the fundamentals of anatomy.
In this short review, we have discussed the symptoms, management, and prevention of brown syndrome.
Keterampilan Komunikasi Guru BK pada Implementasi Kurikulum Merdeka Sistem Pembelajaran yang Fleksibel dalam Menilai Perkembangan Siswa SMK 2 Muhammadiyah Banjarmasin dari Segi Akademik
Authors: Mardiana Mardiana , Rakhmadiansyah Rakhmadiansyah , Farihin Farihin , Maulana Erdyan Jaya , Syahbana Takdir Ali 
Published: April 2024

Penelitian ini menganalis bagaimana Keterampilan Komunikasi Guru BK Pada Implementasi Kurikulum Merdeka Sistem Pembelajaran Yang Fleksibel Dalam Menilai Perkembangan Siswa SMK 2 Muhammadiyah Banjarmasin Dari Segi Akademik. Penelitian ini menggunakan metode Deskriptif Kualitatif menggunakan Wawancara dengan Para Informan. Hasil menunjukkan bahwa Keterampilan Komunikasi Guru BK Pada Implementasi Kurikulum Merdeka Sistem Pembelajaran Yang Fleksibel Dalam Menilai Perkembangan Siswa SMK 2 Muhammadiyah Banjarmasin Dari Segi Akademik sangatlah berpengaruh dan hal tersebut dipengaruhi oleh Kurikulum Merdeka itu sendiri dimana Kurikulum Merdeka dengan sistem Pembelajaran yang Fleksibel meningkatkan kemampuan mengajar para guru dan belajar para siswa yang mendorong kreativitas. Pada Kurikulum merdeka peran guru BK sangat besar dalam jenjang karir para siswa, sistem yang fleksibel ini lah yang membuat kedekatan antara guru BK dan para siswa menjadi dekat yang membuat para siswa percaya dengan para guru.
Implementasi Cloud Computing dengan Google Colaboratory pada Aplikasi Pengolah Data Zoom Participants
Authors: Soen Gabriel Irfon Elrohi , Marlina Marlina , Renny Renny 
Published: April 2024

Since COVID-19 pandemic, many activities in the world of education, business, and religion, have become online. One of the online video conferencing applications that is often used is Zoom meeting. Due to the lockdown imposed by the government, the use of this application has increased. Even though the paid version has been used, there are still some difficulties for users to know the contributions of participants in meetings via Zoom Meetings, namely to know the data on the duration of participants’ attendance who attend meetings via Zoom and to sort out whether participants attend this meeting from beginning to end. Likewise, if the Zoom recording is stored on a computer or smartphone, it can be lost at any time due to various things.
This problem can be solved by using Cloud Drive as the data repository and adding a python script to Google Colaboratory, so it can produce an application that can monitor the activity of each participant in the zoom participant data. After the implementation of the Google Colaboratory at ROCK church Makassar and by taking zoom data for 1 year, the results of the Google Colaboratory platform for the zoom participant data application, produce 3 graphs; a duration graph containing name and time duration data, a join leaves time detail graph containing data on names and hours of entry and exit, and a graph of the number of participants per session rundown of events. Additionally, by using this Google Colaboratory, storage becomes easier because it only requires internet, browser, and email.
Google Maps API dalam Perancangan Sistem Informasi Geografis (SIG) Pemetaan Batas Wilayah Universitas Kristen Surakarta
Authors: Ekowati Maria Atik Sunarti , Nindyatama Zefanya Permata , Siagian Rudi Eko Sanjaya 
Published: April 2024

Universitas Kristen Surakarta (UKS) merupakan salah satu universitas sewasta yang ada di kota Surakarta, provinsi jawa tengah. Lokasi kampus berada disebelah timur SMA Negeri 1 dan 2 Surakarta, di sebelah barat SMA Warga Surakarta, sebuah letak yang sangat strategis. Dengan semakin berkembangnya alat bantu aplikasi pemrograman Sistem Informasi Geografis (SIG) saat ini, SIG banyak di dukung program aplikasi lain dalam perkembangannya. Dengan berkembangnya kebutuhan manusia akan informasi cepat, tepat dan akurat maka dalam pemetaan suatu tempat, diperlukan pengembangan teknologi Informasi. Metode yang di pakai sebagai dasar perancangan adalah Aplikasi Google Maps API. Hasil Perancangan Sistem Informasi Geografis Pemetaan Batas Wilayah universitas Kristen Surakarta Berbasis Google Maps API adalah sebuah Website Pemetaan Interaktif yang dapat menampilkan peta batas wilayah kampus Universitas Kristen Surakarta berbasis Google Maps API. Luaran sebuah system Informasi Geografis berbasis Web (WebGIS).
Implementasi Metode WebQual 4.0 untuk Analisis Kualitas Website Universitas Boyolali
Authors: Wahyono Ari , Sanjaya Wisnu 
Published: April 2024

As a higher education institution, Universitas Boyolali (UBY) has an official website with the address https://uby.ac.id. The main website conveys information to the academic community and the public. Website quality measurement is used as a basis for making improvements, so that website performance and quality are better. One of the methods for website measurement is using the WebQual 4.0 method. WebQual 4.0 Method measures a website's quality and focuses on three main dimensions: usability, information quality, and interaction service quality.
This study aims to use the Webqual 4.0 method to measure quality with the website research object owned by Boyolali University, namely https://uby.ac.id. The study used 174 respondents using the non-probability incidental sample method for students, teaching staff, and lecturers at Boyolali University who had visited or accessed the website. The analysis results show that the Usability Dimension gets a percentage value of 78.62%, the Information Quality dimension is 78.22%, and service interaction is 77.75%. These results indicate that a percentage of respondents stated that they were satisfied with the quality of the UBY website.
ANALISA KEBERHASILAN BISNIS KECIL
Authors: Soehari Hartoyo 
Published: April 2024

Small businesses play a vital role in economic development globally, contributing significantly to employment, innovation, and GDP growth. However, they face numerous challenges that affect their success rates. Understanding the factors influencing small business success is crucial for policymakers, entrepreneurs, and stakeholders to formulate effective strategies and support mechanisms. The study aims to determinne factors supporting the success of small cullinary business for 50 years. The trade is bakso, meat soup, in Pemalang District, Central Java, Indonesia. The study adopts qualitative method. Information were collected through an interview with the owner and families. The study found that enterpreneaur skill, raw materials, finance. Technology, and marketing, are pillar factors to succeed the business.
Pathogenetic and Clinical Relationships between Chronic Obstructive Pulmonary Disease, Sarcopenia and Frailty
Authors: Sergeeva V. A. , Runikhina N. K. 
Published: April 2024

The impact of aging and geriatric syndromes on chronic obstructive pulmonary disease, a complex, chronic inflammatory condition, is a subject of significant interest in aging medicine. Understanding the key pathogenic mechanisms that combine the aging process and chronic obstructive pulmonary disease can help rethink therapeutic concepts in patients with the described comorbidity and be considered the basis of new directions for preventive measures.The purpose of the review is to update data from open access scientific sources on the pathogenetic mechanisms and clinical relationships of chronic obstructive pulmonary disease, sarcopenia, and frailty.Methods. Foreign and domestic scientific publications on this topic over the past 15 years were analyzed using electronic libraries PubMed/MedLine, Elsevier, elibrary.Conclusion. An extensive examination of current scientific data was carried out to determine the pathogenetic connections between chronic obstructive pulmonary disease and the aging process, along with the prominent geriatric conditions of sarcopenia and frailty. A significant amount of information has been accumulated indicating deterioration in the clinical manifestations and prognosis of older patients with a combination of the described pathologies; therefore, the relevance of further study of these comorbidities remains. The cause-and-effect relationship of these clinical manifestations remains not entirely clear: chronic obstructive pulmonary disease leads to the development of sarcopenia and frailty, or these geriatric syndromes only accompany chronic obstructive pulmonary disease, as a disease that manifests itself most frequently in advanced age. There is significant interest in developing therapeutic strategies to improve the clinical outcomes of older patients with a combination of chronic obstructive pulmonary disease, frailty and sarcopenia.
Chronic Kidney Disease in Older Adults. Consensus Statement of Russian Association of Gerontologists and Geriatricians, Scientific Society of Nephrologists of Russia and Eurasian Association of Therapists
Authors: Tkacheva O. N. , Kotovskaya Yu. V. , Bobkova I. N. , Shutov A. M. , Villevalde S. V. , Efremova E. V. , Runikhina N. K. , Eruslanova K. A. , Arutyunov G. P. , Batyushin M. M. , Frolova E. V. 
Published: April 2024

The prevalence of chronic kidney disease (CKD) increases with age, but CKD is often underdiagnosed in older adults and regarded as age-related changes of kidney function. Screening for CKD is mandatory in older adults and should include estimated glomerular filtration rate (eGFR) using both the CKD EPI creatinine-based formula and the albumin/creatinine ratio in a urine spot sample. In older adults the diagnostic criteria of CKD are the same as in younger subjects. CKD is associated with advanced ageing and requires careful assessment of geriatric syndromes. Renal function should be assessed at least annually, considering a rate of decline in eGFR greater than 1 ml/min/1.73 m2 per year as significant. Older adults with CKD are characterized by high comorbidity; risk factors for CKD and geriatric syndromes overlap. CKD should be considered among a number of comorbid conditions that increase the risk of deterioration of geriatric status and underline the need for multidisciplinary management based on a comprehensive geriatric assessment. Patients with eGFR <60 ml/min/1.73 m2 should be considered at high risk for renal and extrarenal adverse drug effects. In these patients, inappropriate medications, supplements, and vitamins should be carefully identified and corrected using STOPP/START criteria. eGFR and estimated creatinine clearance should be carefully monitored during treatment with drugs that can potentially affect renal function and/or the dose of which is adjusted based on renal function, as well as during acute illness or exacerbation of chronic conditions.
HUBUNGAN DERAJAT HIPERTENSI DENGAN STADIUM GAGAL GINJAL KRONIK DI UNIT HEMODIALISA RUMAH SAKIT BADAN PENGUSAHAAN BATAM TAHUN 2019-2020
Authors: Fanany Muhammad Azmi , Christina Yani , Nasution Tia Helvita Sari 
Published: April 2024

Background: Chronic Kidney Disease (CKD) is a progressive and irreversible kidney function disorder, in which the body is unable to maintain metabolism and fails to maintain fluid and electrolyte balance which results in an increase in urea.The risk factors for chronic kidney failure from hypertension are 3.2 times greater than those who do not have hypertension.The study aims to determine the relationship between the degree of hypertension and the stage of Chronic Kidney Failure in the hemodialysis unit at Badan Pengusahaan Batam Hospital in 2019-2020. Methods: The research design using analytic observational with a cross sectional approach in the Hemodialysis unit at the Badan Pengusahaan Batam Hospital in July 2023. The sample of this study was 95 patients with Chronic Kidney Failure who visited the Hemodialysis unit at Badan Pengusahaan Batam Hospital in 2019-2020selected by random sampling method. Analysis data using the Chi-Square correlation hypothesis test. Results: A total of 38 people (29.5%) respondents were in the age group 46-55 years and 48 people (50.5%) respondents were male, 62 people (65.3%) had grade 2 hypertension, 83 people(87.4%) of respondents had stage V chronic kidney failure. There was a significant relationship between the degree of hypertension and the stage of chronic kidney failure in patients at the Hemodialysis Unit RSBP Batam 2019-2020 (p=0.042). Conclusion: There is a significant relationship between the degree of hypertension and the stage of chronic kidney failure in patients at the RSBP Batam Hemodialysis Unit 2019-2020.
Pipeline Provenance for Analysis, Evaluation, Trust or Reproducibility
Authors: Johnson Michael A. C. , Klöckner Hans-Rainer , Muzafarova Albina , Lackeos Kristen , Champion David J. , Dembska Marta , Schindler Sirko , Paradies Marcus 
Published: April 2024

Abstract
Data volumes and rates of research infrastructures will continue to increase in the upcoming years and impact how we interact with their final data products. Little of the processed data can be directly investigated and most of it will be automatically processed with as little user interaction as possible. Capturing all necessary information of such processing ensures reproducibility of the final results and generates trust in the entire process. We present Pipeline pRovenance for Analysis, Evaluation, Trust Or Reproducibility (PRAETOR), a software suite that enables automated generation, modeling, and analysis of provenance information of Python pipelines. Furthermore, the evaluation of the pipeline performance, based upon a user defined quality matrix in the provenance, enables the first step of machine learning processes, where such information can be fed into dedicated optimization procedures.
Optimization of the OEE indicator through meta-models’ simulation in the buffer allocation problem
Authors: Hernández Vázquez José Israel , Hernández Vázquez José Omar , Hernández González Salvador , Olivares Vera Daniel Arturo 
Published: April 2024

Purpose: The buffer allocation problem (BAP) arises in the design of production systems; it involves analyzing and defining the optimal distribution of buffers within a production line. This paper presents a BAP formulation in a parallel series line from a cup sublimation process with unreliable operating conditions. The main objective of this study is to develop a new BAP solution proposal, considering the optimization of the OEE indicator used in Lean Manufacturing.Design/methodology/approach: The BAP was analyzed under an optimization approach from two different criteria: firstly, the maximization of the OEE indicator (Overall Equipment Effectiveness) utilized in Lean Manufacturing, as well as the maximization of the average production rate (Throughput). The case study involves unreliable operating conditions. Process times, and timeframes between failures and repairs, consider normal distribution functions. The evaluation method employed in the study includes the use of simulation meta-models built from experiment designs and production line simulations; on the other hand, the nonlinear GRG algorithm is used to solve the mathematical models.Findings: In the study carried out, it is shown that the OEE indicator can be affected when more buffers are allocated than necessary, hence it is important to calculate and establish the best configuration for them through an analysis such as the one proposed in this document.Research limitations/implications: The research is limited to a case study of an unreliable production line from a cup sublimation process.Practical implications: The proposed solution established in this study can be used in other production lines with configurations different from the one analyzed, considering the optimization criterion of the OEE indicator. Originality/value: Seeking that the allocation of buffers within the production line improves the OEE indicator is something new in the literature, therefore, the results achieved in this research become even more relevant.
Monophosphoryl Lipid A–based Adjuvant to Promote the Immunogenicity of Multivalent Meningococcal Polysaccharide Conjugate Vaccines
Authors: Alugupalli Kishore R 
Published: April 2024

Abstract
Activation of the adaptive immune system requires the engagement of costimulatory pathways in addition to B and T cell Ag receptor signaling, and adjuvants play a central role in this process. Many Gram-negative bacterial polysaccharide vaccines, including the tetravalent meningococcal conjugate vaccines (MCV4) and typhoid Vi polysaccharide vaccines, do not incorporate adjuvants. The immunogenicity of typhoid vaccines is due to the presence of associated TLR4 ligands in these vaccines. Because the immunogenicity of MCV4 is poor and requires boosters, I hypothesized that TLR4 ligands are absent in MCV4 and that incorporation of a TLR4 ligand–based adjuvant would improve their immunogenicity. Consistent with this hypothesis, two Food and Drug Administration–approved MCV4 vaccines, MENVEO and MenQuadfi, lack TLR4 ligands. Admixing monophosphoryl lipid A, a TLR4 ligand–based adjuvant formulation named “Turbo” with MCV4 induced significantly improved IgM and IgG responses to all four meningococcal serogroup polysaccharides in adult and aged mice after a single immunization. Furthermore, in infant mice, a single booster was sufficient to promote a robust IgG response and 100% seroconversion when MCV4 was adjuvanted with Turbo. Turbo upregulated the expression of the costimulatory molecules CD40 and CD86 on B cells, and Turbo-driven adjuvanticity is lost in mice deficient in CD40 and CD86. These data suggest that Turbo induces the required costimulatory molecules for its adjuvant activity and that incorporation of Turbo could make bacterial polysaccharide vaccines more immunogenic, minimize booster requirements, and be cost-effective, particularly for those individuals in low- and middle-income and disease-endemic countries.