bluuebunny/crossref_metadata_2025_split huggingface dataset:
Synthesis of the Substituted 3‐Cyclobutene‐1,2‐diones.
Authors: Ivanovsky Sergey A. , Dorogov Mikhail V. , Kravchenko Dmitry V. , Ivachtchenko Alexandre V. 
Published: December 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Highly Regio‐ and Stereoselective Palladium(0)‐Catalyzed Addition of Organoboronic Acids with 1,2‐Allenic Sulfones, Sulfoxides, or Alkyl‐ or Aryl‐Substituted Allenes in the Presence of Acetic Acid: An Efficient Synthesis of (E)‐Alkenes.
Authors: Guo Hao , Ma Shengming 
Published: December 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Sodium Dithionite Initiated Addition of CF2Br2, CF3I and (CF3)2CFI to Allylaromatics. Synthesis and the Reactivity of 4‐Aryl‐1,1‐difluorodienes and 4‐Aryl‐1,1‐bis(trifluoromethyl)dienes.
Authors: Ignatowska Jolanta , Dmowski Wojciech 
Published: December 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Preparation of Polyfunctional Aryl Triazenes via a Direct Insertion Reaction of Zn in the Presence of LiCl.
Authors: Liu Ching‐Yuan , Knochel Paul 
Published: December 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
DMAP‐Catalyzed Benzannulation of Ethyl Propiolate with β‐Dicarbonyl Moieties.
Authors: Zhou Qing‐Fa , Yang Fei , Guo Qing‐Xiang , Xue Song 
Published: December 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Sulfated Zirconia (SO4/ZrO2) as a Reusable Solid Acid Catalyst for the Mannich‐Type Reaction Between Ketene Silyl Acetals and Aldimines.
Authors: Wang Sainan , Matsumura Shuichi , Toshima Kazunobu 
Published: December 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Synthesis and in vitro Antitumor Activity of a New Series of 4‐Chloro‐2‐mercapto‐5‐methylbenzenesulfonamide Derivatives.
Authors: Slawinski J. , Brzozowski Z. 
Published: December 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Chitosan‐Supported Palladium(0) Catalyst for Microwave‐Prompted Suzuki Cross‐Coupling Reaction in Water.
Authors: Yi Song‐Se , Lee Dong‐Ho , Sin Eunyoung , Lee Yoon‐Sik 
Published: December 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Palladium Catalyzed Decarbonylative Mizoroki—Heck Reactions of Benzoyl Chloride and Styrene under Microwave Irradiation.
Authors: de Luna Martins Daniela , Alvarez Heiddy M. , Aguiar Lucia C. S. , Antunes O. A. C. 
Published: December 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Reductive Ring Opening Reactions of Diphenyldihydrofullerenylpyrroles.
Authors: Hawkins Bill C. , Keller Paul A. , Pyne Stephen G. 
Published: December 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Fluoroalkylation of Pent‐4‐en‐1‐ols Initiated by Sodium Dithionite to Synthesize Fluorine‐Containing Tetrahydrofuran Derivatives.
Authors: Yang Yueyan , Wang Zhonghua , Zhu Yaoping , Fang Xiang , Yang Xianjin , Wu Fanhong , Shen Yongjia 
Published: December 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Condensation of 4‐Aryl‐4‐oxobutanoic Acids with Benzylamines: Synthetic and Structural Studies on 1‐Arylmethyl‐3‐ [(E)‐1‐arylmethylidene]‐5‐phenyl‐2,3‐dihydro‐1H‐2‐pyrrolones.
Authors: Rao H. Surya Prakash , Senthilkumar S. , Gopu K. , Rafi Shaik 
Published: December 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
A New Method for Annulation of the α‐Pyrone Ring.
Authors: Traven V. F. , Voevodina I. V. , Manaev A. V. , Podkhalyuzina N. Ya. 
Published: December 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Synthesis and Antidiabetic Activity of Some New Chromonyl‐2,4‐thiazolidinediones.
Authors: Bozdag‐Duendar Oya , Ceylan‐Uenluesoy Meltem , Verspohl Eugen J. , Ertan Rahmiye 
Published: December 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
A Novel One‐Pot Oxidative Cyclization of 2′‐Amino and 2′‐Hydroxychalcones Employing FeCl3×6H2O—Methanol. Synthesis of 4‐Alkoxy‐2‐aryl‐quinolines and Flavones.
Authors: Kumar Kalvi Hemanth , Perumal Paramasivan T. 
Published: December 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
N‐Tosylcarbamide Derivatives of 2‐Pyridinium and 2‐Pyrimidinium — A New Class of Inhibitors of Metabolically Excitable Potassium Channels in Cells of the Myocardium.
Authors: Stankevicius A. P. , Janusene L. N. , Gendviliene V. I. , Gurskaite G. A. , Zablockaite D. P. 
Published: December 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Condensed Isoquinolines. Part 20. Characteristic Features of Thermal Rearrangement of 7,12‐Dihydro‐5H‐isoquino[2,3‐a]quinazolin‐5‐one to Form 6,11‐Dihydro‐13H‐isoquino[3,2‐b]quinazolin‐13‐one.
Authors: Potikha L. M. , Kovtunenko V. A. , Tarasevich A. V. , Wolf J. G. , Andre Ch. 
Published: December 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Synthesis of 3‐Substituted‐5‐ (4‐carboxycyclohexylmethyl)‐tetrahydro‐2H‐1,3,5‐thiadiazine‐2‐thione Derivatives as Antifibrinolytic and Antimicrobial Agents.
Authors: Oezcelik Azime Berna , Ersan Seyhan , Ural Ali Ugur , Oezkan Semiha , Ertan Mevluet 
Published: December 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Synthesis of the First Example of a Tetrahydroindeno[2,1‐c]azonine System by the Reaction of 2,3‐Dihydro‐1H‐indeno[2,1‐c]pyridinium Methylide with Methyl Acetylenedicarboxylate.
Authors: Soldatenkov A. T. , Volkov S. V. , Soldatova S. A. 
Published: December 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Efficient Synthesis of Functionalized Spiro‐2,5‐dihydro‐1,2‐λ5‐oxaphospholes.
Authors: Yavari Issa , Hossaini Zinatossadat , Sabbaghan Maryam , Ghazanfarpour‐Darjani Majid 
Published: December 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Assignment of the Absolute Configuration of the Marine Pentacyclic Polyether (+)‐Enshuol by Total Synthesis.
Authors: Morimoto Yoshiki , Yata Hiromi , Nishikawa Yoshihiro 
Published: December 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Further New Cembranoid Diterpenes from the Hainan Soft Coral Sarcophyton latum.
Authors: Yan Xiao‐Hong , Li Zhen‐Yu , Guo Yue‐Wei 
Published: December 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Stereocontrolled Synthesis of Dafachronic Acid A, the Ligand for the DAF‐12 Nuclear Receptor of Caenorhabditis elegans.
Authors: Giroux Simon , Corey E. J. 
Published: December 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Lipase‐Catalyzed Kinetic Resolution of 2‐Nitro Alcohol: Total Synthesis of Taxol Side Chain and (‐)‐Bestatin.
Authors: Gogoi Naminita , Borah Jagat C. , Boruwa Joshodeep , Barua Nabin C. 
Published: December 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Efficient Formation and Cleavage of Benzylidene Acetals by Sodium Hydrogen Sulfate Supported on Silica Gel.
Authors: Niu Youhong , Wang Ning , Cao Xiaoping , Ye Xin‐Shan 
Published: December 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Flabelliformides A (I) and B (II), Two Novel Indole Alkaloids from Ervatamia flabelliformis.
Authors: Liang Shuang , Chen Hai‐Sheng , Shen Yun‐Heng , Jin Li , Zhang Wei‐Dong 
Published: December 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Synthesis of Gallocatechin‐3‐gallate Analogues.
Authors: Vaiana Nadia , Rizzi Luca , Pezzano Maria G. , Restelli Roberto , Rota Filippo , Stefanini Silvia , Vicentini Silvia , Romeo Sergio 
Published: December 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Synthesis of the Sex Pheromone of the Obscure Mealybug, the First Example of a New Class of Monoterpenoids.
Authors: Millar Jocelyn G. , Midland Sharon L. 
Published: December 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
(+)‐Saxitoxin: A First and Second Generation Stereoselective Synthesis.
Authors: Fleming James J. , McReynolds Matthew D. , Du Bois J. 
Published: December 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Synthesis and Evaluation of Potent and Selective β3 Adrenergic Receptor Agonists Containing Heterobiaryl Carboxylic Acids.
Authors: Shearer Barry G. , et al. et al. 
Published: December 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Structure, Magnetism, and Thermodynamics of the Novel Rare Earth‐Based Ln5T4 Intermetallics
Authors: Pecharsky V. K. , Gschneidner K. A. Jr. 
Published: December 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Regiodivergent Epoxide Opening: A Concept in Stereoselective Catalysis Beyond Classical Kinetic Resolutions and Desymmetrizations.
Authors: Gansaeuer Andreas , Fan Chun‐An , Keller Florian , Karbaum Peter 
Published: December 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Three‐dimensional distribution patterns of CD34 antigen on nonactivated cord blood cells
Authors: Jung Georges , Wunder Eckart , Dieterlen Alain , Hénon Philippe , Jacquey Serge 
Published: December 2007

AbstractCirculating immature blood cells are inhomogeneous in most cytometric parameters, including CD34 expression. This surface antigen forms patches, and we studied their spatial distribution pattern by processing staggered and digitalized microscopical images; the number, fluorescence intensity, and volume were determined in randomly identified CD34‐positive cord blood cells in suspension. Quantitative fluorescence analysis of individual CD34‐labeled cells was performed after acquisition of microscopical images in high resolution by using a CCD camera and adjacent deconvolution. Two major (n = 42 and n = 41) and one minor (n = 5) group of haematopoietic progenitors with different CD34+ distribution patterns were detected. All CD34 antigen patches are localized on the spherical cell membrane, and differ most significantly in fluorescence intensity (P < 10−4), antigen volume (P < 0.004), and patch number per cell (P < 0.02). If all parameters are employed, 96.6% of CD34+ cells are correctly classified into one of the three groups as shown by discriminant analysis. If fluorescence intensity is eliminated, recognition efficiency decreases to 68.2%, indicating that this is the most powerful single parameter. While total fluorescence intensity is most characteristic for each group, total patch volume and number per cell, and heterogeneity of patch volumes and their spatial distribution also contribute significantly to reliable classification into their groups. © 2007 International Society for Analytical Cytology
Low‐cost enumeration of CD4+ T cells using a density‐based negative selection method (RosetteSep™) for the monitoring of HIV‐infected individuals in non‐OECD countries
Authors: Bold Angelika , Wurth Rainer , Keller Thomas , Trahorsch Ulrike , Voigt Peter , Schubert Stefan , Sack Ulrich 
Published: December 2007

AbstractThe CD4 count is the best surrogate marker for monitoring HIV. The reference method for assessing CD4 counts (flow cytometry, FCM), as expensive technique, is not widely used in non‐OECD countries. To make HIV‐monitoring available to more patients in these countries, we modified a commercially available density‐based negative selection assay (RosetteSep™) to make it applicable for low‐cost cell enumeration. For evaluation (Step 1), blood taken from 25 HIV patients and 29 healthy donors was assayed with the modified negative selection method (MNS) and compared with FCM. For validation (Step 2), this method was performed in blind quintuplicates on 12 HIV+ blood samples according to FDA guidelines. Association of MNS with the FCM is given by regression models for both steps: Step 1: slope = 1.091, intercept = −46.5. Step 2: slope = 1.074, intercept = −38.3 (Step 2). The imprecision of MNS assessed during Step 2 was 21.2% (intraserial) and 18.8% (interserial). The results suggest that MNS is capable of providing an approximate CD4 count. At a cost of 0.30, it is affordable to patients living in resource‐restrained areas. The technique has the potential to deliver an accurate, precise, low‐cost test to monitor HIV+ patients. © 2007 International Society for Analytical Cytology
Total nucleated cell differential for blood and bone marrow using a single tube in a five‐color flow cytometer
Authors: Björnsson Sven , Wahlström Saga , Norström Eva , Bernevi Ingela , O'Neill Ulla , Johansson Eva , Runström Håkan , Simonsson Per 
Published: December 2007

AbstractBackground:Flow cytometry allows the use of several antibodies in addition to light scatter, and most flow cytometers will provide at least seven measurements on each cell passing through the laser beam. A skilled microscopist will classify at least 14 cell classes in bone marrow or blood. Our goal was to use the seven parameters available in our flow cytometer to provide a reliable differential count using only one tube.Methods:Peripheral blood samples were analyzed on the Beckman Coulter LH750 cell counter, and the flagging and messages from the cell counter were used to select normal or pathological samples. Samples without flags (N = 50), with >2% erythroblasts (N = 80), or with “Blast” or “Verify diff” flags (N = 54) were investigated. We used a lyse‐no‐wash method to ensure minimal loss of fragile cells with live gating on DRAQ5‐positive cells to acquire only nucleated cells. The FL‐1 to FL‐4 channels were used for the antibodies CD36‐FITC, CD203‐PE, CD138‐PE, CD45‐ECD, CD16‐Pcy5, and CD56‐Pcy5. FL‐5 was used for the DNA‐stain DRAQ5.Results:Using live gate acquisition on DRAQ5, we were able to classify total nucleated cells into 10 classes. We were unable to identify megakaryocytes, but platelets could be studied by rerunning the sample after dilution and gating on DRAQ5‐negative CD36‐posive events. Validation against digitized microscopy and cell counter showed linear correlations within each cell class with correlation coefficients that seem reasonable for cellular classification. The lowest correlation was found for basophil granulocytes. Flow cytometry detected twice as many immature neutrophils compared to microscopy.Conclusions:We have designed a one‐tube immunophenotyping panel for classification of total nucleated cells and platelets in blood or bone marrow. The seven parameters available in one single tube in our cytometer seem to be enough for reliable differential count even in difficult pathological samples. The analytical imprecision of the flow cytometer differential was much lower than that obtained with microscopy or cell counter differentials. © 2007 Clinical Cytometry Society.
False‐positive interpretations in respiratory cytopathology: Exemplary cases and literature review
Authors: Policarpio‐Nicolas Maria Luisa C. , Wick Mark R. 
Published: December 2007

AbstractPulmonary cytology has progressed over the past decades because of advancement in imaging studies and increased confidence of pathologists in cytomorphologic diagnosis. It has an overall sensitivity and specificity ranging from ∼60 to 96%. However, even with the most conscientious laboratories, false‐positive diagnoses of malignancy do occur in respiratory specimens, potentially resulting in unnecessary treatment and morbidity. Selected respiratory cytopathology cases with false‐positive diagnoses are presented here, along with a review of pertinent literature and a discussion of possible steps to minimize the problem being considered. Diagn. Cytopathol. 2008;36:13–19. © 2007 Wiley‐Liss, Inc.
Utility of WT‐1, p63, MOC31, mesothelin, and cytokeratin (K903 and CK5/6) immunostains in differentiating adenocarcinoma, squamous cell carcinoma, and malignant mesothelioma in effusions
Authors: Pu Robert T. , Pang Yijun , Michael Claire W. 
Published: December 2007

AbstractTo distinguish carcinoma, either adenocarcinoma (ADC) or squamous cell carcinoma (SCC), and malignant mesothelioma (MM) in effusion can be a diagnostic challenge based on morphology alone. This study evaluates the utility of WT‐1, p63, MOC31, mesothelin, and cytokeratin (K903 and CK5/6) immunostains in effusions when ADC and SCC of the lung are in the differential diagnosis with MM. A cohort of 43 effusions consisting of lung ADC (N = 10), SCC (N = 15), and MM (N = 18, mostly (16) pleural based), was subjected to immunostains using the above mentioned antibodies. WT‐1 was positive in 100% MM, 0% ADC, and 0% SCC cases while p63 was positive in 0% MM, 30% ADC, and 80% SCC cases. Stain for MOC31 was positive in 100% ADC, 67% SCC, and 35% MM cases. Similarly, mesothelin antibody stained 100% ADC, 60% SCC, and 47% MM cases. Antibodies for K903 and CK5/6 stained 100% SCC cases but fewer ADC cases (40 and 10%, respectively). In conclusion, in this cohort of mostly pleural malignant effusion, MM can be identified with positive staining for WT‐1 and negative staining for p63. Conversely, negative staining with WT‐1 and positive staining for p63 exclude MM. Used as part of an immunostain panel, cytokeratin markers (CK5/6 and K903) are useful in differentiating SCC from ADC when MM is already excluded, and MOC31 might have limited value in differentiating ADC from MM. A negative stain with MOC31 can exclude lung ADC. Mesothelin, on the other hand, is not useful in the differential diagnosis of ADC, SCC, and MM. Diagn. Cytopathol. 2008;36:20–25. © 2007 Wiley‐Liss, Inc.
Paternally and maternally transmitted GAL4 transcripts contribute to UAS transgene expression in early Drosophila embryos
Authors: Tzortzopoulos Athanasios , Skoulakis Efthimios M.C. 
Published: December 2007

AbstractThe GAL4/UAS binary system with its recent modifications provides a powerful tool to study gene function in Drosophila enabling control over the timing, tissue specificity, and magnitude of gene expression. GAL4 expression during early embryonic stages has been well determined for certain driver lines, but for some of the commonly used in Drosophila research it is unknown, or partially determined. By monitoring the developmental kinetics of GAL4 expression and transgene transcription, we show that particular GAL4 drivers transiently direct ectopic expression of UAS‐linked transgenes at early stages of embryogenesis in a GAL4‐ dependent manner via a mechanism that involves parental transmission of Gal4 transcripts. genesis 45:737–743, 2007. © 2007 Wiley‐Liss, Inc.
Genetic analysis of attractin homologs
Authors: Walker Will P. , Aradhya Swaroop , Hu Che‐Lin , Shen Shiliang , Zhang Wei , Azarani Arezou , Lu XinYun , Barsh Gregory S. , Gunn Teresa M. 
Published: December 2007

AbstractAttractin (ATRN) and Attractin‐like 1 (ATRNL1) are highly similar type I transmembrane proteins. Atrn null mutant mice have a pleiotropic phenotype including dark fur, juvenile‐onset spongiform neurodegeneration, hypomyelination, tremor, and reduced body weight and adiposity, implicating ATRN in numerous biological processes. Bioinformatic analysis indicated that Atrn and Atrnl1 arose from a common ancestral gene early in vertebrate evolution. To investigate the genetics of the ATRN system and explore potential redundancy between Atrn and Atrnl1, we generated and characterized Atrnl1 loss‐ and gain‐of‐function mutations in mice. Atrnl1 mutant mice were grossly normal with no alterations of pigmentation, central nervous system pathology or body weight. Atrn null mutant mice carrying a β‐actin promoter‐driven Atrnl1 transgene had normal, agouti‐banded hairs and significantly delayed onset of spongiform neurodegeneration, indicating that over‐expression of ATRNL1 compensates for loss of ATRN. Thus, the two genes are redundant from the perspective of gain‐of‐function but not loss‐of‐function mutations. genesis 45:744–756, 2007. © 2007 Wiley‐Liss, Inc.