bluuebunny/crossref_metadata_2025_split huggingface dataset:
Parkinson's disease due to the R1441G mutation in Dardarin: A founder effect in the basques
Authors: Simón‐Sánchez Javier , Martí‐Massó José‐Félix , Sánchez‐Mut José Vicente , Paisán‐Ruiz Coro , Martínez‐Gil Angel , Ruiz‐Martínez Javier , Sáenz Amets , Singleton Andrew B. , López de Munain Adolfo , Pérez‐Tur Jordi 
Published: September 2006

AbstractThe recent discovery of mutations in Dardarin (LRRK2) have been related to the appearance of Parkinson's disease in several families. Notably, one single mutation in this gene (R1441G) not only appeared in familial, but also in apparently sporadic Parkinson disease (PD) patients of Basque descent. A clinical population was ascertained, and subjects were classified into Basque and non‐Basque descent according to their known ancestry. The R1441G mutation was assayed using an allele‐specific polymerase chain reaction, and several single nucleotide polymorphisms surrounding this mutation were analyzed by direct sequencing. In addition to 22 members of the original Basque families where R1441G was identified, we observed 17 carriers of the mutation who were apparently related through a common ancestor. From a clinical perspective, the disease observed in mutation carriers is indistinguishable from that in noncarriers. The R1441G mutation causes a form of Parkinson's disease that is equivalent to that observed in idiopathic Parkinson's disease. This mutation appears in 16.4% and 4.0% of familial and sporadic PD in this Basque population, respectively. © 2006 Movement Disorder Society
The structure of ammonium pyrazolates in the solid state
Authors: Navarro Pilar , Reviriego Felipe , Alkorta Ibon , Elguero José , López Concepción , Claramunt Rosa M. , García‐España Enrique 
Published: September 2006

AbstractThe crystals obtained by mixing equimolar amounts of diethyl 1H‐pyrazole‐3,5‐dicarboxylate and the primary amines phenethylamine and homoveratrylamine are ammonium pyrazolate salts as determined by 13C and 15N CPMAS NMR. Copyright © 2006 John Wiley & Sons, Ltd.
Simplification of the 1H NMR spectra of enantiomers dissolved in chiral liquid crystals, combining variable angle sample spinning and selective refocusing experiments
Authors: Beguin Laetitia , Courtieu Jacques , Ziani Latifa , Merlet Denis 
Published: September 2006

AbstractThis work presents a technique to simplify overcrowded proton spectra in chiral liquid crystal solvents using rotation of the sample near the magic angle, VASS, combined with homonuclear selective refocusing 2D NMR experiments, SERF. This methodology provides a powerful tool to visualise enantiomers out of unresolved proton spectra. A modified SERF sequence is presented where the resulting 2D spectrum can be phased to increase the resolution. Accurate enantiomeric excesses are determined that are not possible to measure on static samples. Two examples are presented. Copyright © 2006 John Wiley & Sons, Ltd.
Erratum: Xyloccensin X and Y, two new limonoids from xylocarpus molluccensis: NMR investigation in mixture
Authors: Deb Roy Abhijeet , Kumar Rajesh , Gupta Poonam , Khaliq Tanvir , Narender Tadigoppula , Aggarwal Vijailakshmi , Roy Raja 
Published: September 2006

AbstractThe original article to which this Erratum refers was published in Magnetic Resonance in Chemistry, on 15 August 2006.
Donors and fundraising in the 2004 presidential campaigns
Authors: Graf Joseph 
Published: September 2006

AbstractThis article is adapted from the report “Small Donors and Online Giving: A Study of Donors to the 2004 Presidential Campaigns,” written by Joseph Graf, Grant Reeher, Michael J. Malbin, and Costas Panagopoulos. Washington, D.C.: Institute for Politics, Democracy and the Internet, George Washington University, and Campaign Finance Institute, March, 2006. 64 pages. www.ipdi.org and www.cfinst.org.
Evaluation of a pediatric palliative care educational workshop for oncology fellows
Authors: Baughcum Amy E. , Gerhardt Cynthia A. , Young‐Saleme Tammi , Stefanik Regina , Klopfenstein Kathryn J. 
Published: September 2006

AbstractBackgroundRecent efforts have focused on improving pediatric palliative care to relieve physical and psychological suffering throughout the course of illness, as well as to improve care at the end‐of‐life (EOL). One area of attention has been medical training, as healthcare providers have often reported feeling ill‐equipped to manage EOL issues. As a pilot study, we developed and evaluated a daylong educational workshop on pediatric palliative care for oncology fellows.ProcedureFellows (N = 32) from 20 hospitals participated in one of two workshops covering palliative care topics, such as pain/symptom management, communication, ethics, and bereavement. Training, knowledge, behavior, and attitudes regarding pediatric palliative care were assessed before the workshop, and knowledge was re‐assessed immediately afterwards.ResultsFellows reported a general lack of training in EOL care, and only 41% rated their education as at least “somewhat” adequate. Colleagues and personal experience were more often sources on EOL care, rather than formal classes or textbooks. Although fellows reported open attitudes toward palliative care, such as involving adolescents in decision‐making, only half felt comfortable in the presence of a dying person. Fewer than half felt comfortable providing EOL care, managing families' expectations, or knowledgeable enough to discuss hospice with patients/families. Following the workshop, knowledge of palliative care increased significantly from 75 to 85% correct.ConclusionsFellows reported open beliefs about palliative care, but acknowledged weaknesses in their training and level of competence. The workshop showed efficacy in improving knowledge, but additional research is needed to evaluate larger educational initiatives and their long‐term impact on clinical services and family satisfaction. Pediatr Blood Cancer 2007;49:154–159. © 2006 Wiley‐Liss, Inc.
Non‐hematopoietic stem cell transplantation treatment of juvenile myelomonocytic leukemia: A retrospective analysis and definition of response criteria
Authors: Bergstraesser Eva , Hasle Henrik , Rogge Tim , Fischer Alexandra , Zimmermann Martin , Noellke Peter , Niemeyer Charlotte M. 
Published: September 2006

AbstractBackgroundJuvenile myelomonocytic leukemia (JMML) is a rare myeloproliferative disease of infancy. Allogeneic hematopoietic stem cell transplantation (HSCT) is currently the only curative treatment modality, while the role of anti‐leukemic therapy prior to HSCT is uncertain. A comparative evaluation of the efficacy of different clinical protocols and great variety of anti‐neoplastic drugs applied pre‐HSCT is hampered by the lack of uniform criteria of response. Classification schemas applied in other forms of leukemia are of little value, because in JMML therapy may result in divergent responses in solid organs compared to peripheral blood (PB).ProcedureWe therefore defined separate response criteria for white blood count (WBC), platelet count, liver size, and spleen size. We then retrospectively evaluated the efficacy of 129 treatment courses other than HSCT administered to 63 children with JMML. Treatment consisted of intensive therapy according to AML‐type chemotherapy, maintenance‐type combination therapy, and single agent therapy. To account for the variability observed in the natural course of disease, we also evaluated 32 episodes of “no therapy.”ResultsBest responses within 3 months of initiation of therapy were highly variable for the four response criteria. In contrast to platelet count and liver size, there was a significant correlation between WBC or spleen size and therapy. Response rates for WBC and spleen size were best for purine analogs, etoposide, and cytarabine as single agents or for maintenance‐type combination therapy.ConclusionTo rigorously test future therapeutic strategies in this rare disease an international consensus on the definition of response criteria will be helpful. Pediatr Blood Cancer 2007;49:629–633. © 2006 Wiley‐Liss, Inc.
Acute transient encephalopathy following paclitaxel treatment in an adolescent with a recurrent suprasellar germinoma
Authors: Rook James , Rosser Tena , Fangusaro Jason , Finlay Jonathan 
Published: September 2006

AbstractPaclitaxel is an antineoplastic agent that is used in the treatment of a variety of solid tumors. Dose‐limiting side effects of myelosuppression and peripheral neuropathy are well known. Paclitaxel has minimal penetration of the blood‐brain barrier and central nervous system side effects are rare. However, transient encephalopathy following paclitaxel infusion has been described in adults but not in children. We present the case of a 14‐year‐old female with a recurrent suprasellar germinoma who developed an acute encephalopathy 4–6 hr following paclitaxel infusion. Pediatr Blood Cancer 2008;50:699–700. © 2006 Wiley‐Liss, Inc.
Acute myelogenous leukemia associated with Ollier disease
Authors: White Matthew S. , Martin Paul L. , McLean Thomas W. 
Published: September 2006

AbstractOllier disease is a rare disorder characterized by the presence of multiple enchondromas and a propensity to develop malignancies. We report the case of a 7‐year‐old Caucasian male with Ollier disease who developed acute myelogenous leukemia (AML). This report describes a patient with Ollier disease and AML and may offer a clue into the genetic pathogenesis of these disorders. Pediatr Blood Cancer 2008;50:645–646. © 2006 Wiley‐Liss, Inc.
Screening new cancer patients for psychological distress using the hospital anxiety and depression scale
Authors: Sellick Scott M. , Edwardson Alan D. 
Published: September 2006

AbstractThe diagnosis of a life‐threatening illness creates immediate psychosocial distress for the patient and his or her family. The threat is real and the rational response is to be afraid. We need to be reaching out to patients and their families and not waiting for crises. The responsibility remains with the healthcare system and psychosocial healthcare professionals to identify those who are in most need. Psychological distress is something that can be relatively easily measured and responded to when psychosocial oncology healthcare professionals are immediately available to address those needs. This paper describes the process used to gather this information, how that information has been used by the psychosocial clinicians in the Supportive Care programme, and what we have learned, in terms of a retrospective data analysis, about our patient population. At the Cancer Centre in Thunder Bay, Ontario, Canada new cancer patients complete the HADS on the day of their first appointment. Since October 2000 we have collected baseline psychological distress data for 3,035 new cancer patients who fully completed all 14 items on the HADS. Of those, 781 patients, or 25.7%, scored above cut‐off points and were given a telephone call. We were able to contact 607 (or 77.7%) of these patients. Five hundred and eight (or 83.7%) of those contacted made, and subsequently attended, one or more appointments with a psychosocial counsellor. Copyright © 2006 John Wiley & Sons, Ltd.
Magnetization and quadrupolar plateaus in the one‐dimensional antiferromagnetic spin‐3/2 and spin‐2 Blume–Capel model
Authors: Aydıner Ekrem , Akyüz Cenk , Gönülol Meltem , Polat Hamza 
Published: September 2006

AbstractWe employed the classical transfer matrix technique to investigate the magnetization and quadrupolar plateaus, phase diagrams and other thermodynamical properties of the one‐dimensional antiferromagnetic spin‐3/2 and spin‐2 Blume–Capel model in the presence of an external magnetic field at very low temperatures. We showed that single‐ion anisotropy is one of the indispensable ingredients for an energy gap which causes to magnetization and quadrupolar plateaus in one‐dimensional antiferromagnetic Ising spin chains. Other thermodynamical predictions seem to be provide this argument. (© 2006 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
ESR studies of gas adsorption on carbon nanotubes
Authors: Clewett Catherine F. M. , Kombarakkaran Justine , Pietraß Tanja 
Published: September 2006

AbstractThe effect of gas adsorption on different carbon nanotube systems is studied using ESR spectrosocpy. One system consists of purified and unpurified single‐walled carbon nanotubes, one of unpurified multi‐walled tubes, and one of multi‐walled tubes where defects have been introduced purposefully at different levels. In single‐ and multi‐walled tubes, hydrogen adsorbs preferentially on defects. Electron‐donating ammonia seems to affect the interlayer interaction in multi‐walled carbon nanotubes. (© 2006 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
Progress in single‐walled carbon nanotube based nanoelectromechanical systems
Authors: Meyer Jannik C. , Cech Jirka , Hornbostel Björn , Roth Siegmar 
Published: September 2006

AbstractWe present torsional pendulums based on small bundles of single‐walled carbon nanotubes and ultimately on individual single‐walled carbon nanotubes. The nanotubes serve as mechanical support and torsional spring for a lithographically defined metal plate. The plate can be actuated in an electric field and the device is operated inside the transmission electron microscope. In comparison with previous works we have built mechanically much more fragile devices, i.e. almost three orders of magnitude heavier suspended metal structures, and metal blocks suspended on smaller diameter nanotubes. (© 2006 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
Transition from Coulomb blockade to insulator regime in multiwall carbon nanotubes
Authors: Dayen J.‐F. , Jehl X. , Wade T. L. , Sanquer M. , Wegrowe J.‐E. 
Published: September 2006

AbstractAn experimental study of electronic transport at very low temperature of multiwall carbon nanotubes is presented. We observed two manifestations of a transition from a Coulomb blockade regime to an insulator regime. The first one is on the temperature dependence of the sample resistance, changing from a power law regime to an activated law at a transition temperatureTC. The second one manifests itself belowTCin the dV/dI(V) profile: at a threshold voltageVCthe resistance changes abruptly from an insulating state to a Coulomb blockade regime characterized by a power law dependence on the voltage. Influence of disorder on Coulomb blockade regime is also enlightened. (© 2006 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
Tube–tube interaction in double‐wall carbon nanotubes
Authors: Pfeiffer R. , Simon F. , Kuzmany H. , Popov V. N. , Zólyomi V. , Kürti J. 
Published: September 2006

AbstractIn a Raman map of double‐wall carbon nanotubes, the radial breathing modes of the inner tubes are grouped into clusters with similar resonance behavior. These clusters are located close to the resonances of SDS wrapped HiPco tubes and can spread over 30 cm–1. Compared to the HiPco tubes the resonances of the inner tubes are shifted about 50 meV to the red. Each cluster represents one fixed inner tube type in several different outer tube types and each component of a cluster originates from a well defined inner/outer tube pair. Elaborate inter‐shell interaction models showed an increasing charge transfer from the outer to inner tube with decreasing diameter difference. Additionally, many DWCNTs systems seem to be metallic, i.e. they have a finite density of states at the Fermi level. (© 2006 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
Mechanico‐chemical interaction of SWNTs with different host matrices evidenced by SERS spectroscopy
Authors: Lefrant Serge , Baibarac Mihaela , Mihut Lucian , Baltog Ioan 
Published: September 2006

AbstractSurface enhanced Raman scattering (SERS) performed with 676.4 and 1064 nm excitations were used to investigate single‐walled carbon nanotubes (SWNTs) thin films prepared from platelets obtained by non‐hydrostatic compression at 0.58 GPa. SWNTs were compressed alone or dispersed into chemical reactive and non‐reactive host matrices. SERS spectra indicate that by compression, SWNTs break into fragments of different sizes, which in turn can react or not with the host matrix. In inorganic hosts (KI, Ag) donor‐acceptor complexes are formed. The appearance of short fragments of SWNTs with a closed‐shell fullerenes behaviour is revealed in SERS spectra. This typical signature appears in the Raman spectrum as a line at ca. 1460 cm–1 associated with a pentagonal pinch mode. (© 2006 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
Pulsed and cw EPR studies on hydrogen atoms encaged in octasilsesquioxane molecules
Authors: Schoenfeld R. S. , Harneit W. , Paech M. 
Published: September 2006

AbstractWe report on the synthesis of hydrogen atoms in different Si8O12R8 cages (R = (CH2)n H with n = 0–3) by both radiation chemistry and ion implantation. The efficiencies of both mechanisms have been studied quantitatively and attempts to optimise the process have been made. Spectral properties and relaxation times were investigated using both cw and pulsed EPR measurements. The Hahn Echo decay behaviour and the dependence of T 1 and T 2 on the side groups R of the cage revealed information about the predominant relaxation mechanisms. (© 2006 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
Conducting and transparent SWNT/polymer composites
Authors: Dettlaff‐Weglikowska Urszula , Kaempgen Martti , Hornbostel Bjoern , Skakalova Viera , Wang Jianping , Liang Jindong , Roth Siegmar 
Published: September 2006

AbstractFlexible, transparent and conducting poly(methyl methacrylate) (PMMA) composites films were prepared using SOCl2 functionalized SWNTs. Optical absorption spectra measured on composite films confirm that the composite preparation procedure preserves the electronic properties (position of the Fermi level) of the p‐doped nanotubes in the polymer matrix. Due to the doping effect of SOCl2 the electrical conductivity of the composites is improved by a factor of 5. The light transmission of the composite films depends on the film thickness and on the nanotube concentration. The optical transmittance of visible light at 500 nm was found to be 92% for 0.1 wt% SWNT loading and 46% for 0.5 wt% SWNT loading. The thickness of the specimens was approximately 20 µm. Conductivity measurement of the thin films performed with the four lead method revealed values 3.5 × 10–3 S/cm and 4.7 × 10–1 S/cm, respectively. (© 2006 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
Unusual transport properties in carbon based nanoscaled materials: nanotubes and graphene
Authors: Purewal M. S. , Zhang Y. , Kim P. 
Published: September 2006

AbstractThe massless Dirac particle moving at the speed of light has been a fascinating subject in relativistic quantum physics. Nanoscale graphitic materials, such as carbon nanotubes and graphene, now provide us with an opportunity to investigate such exotic effects in low‐energy condensed matter systems. The unique electronic band structure of graphene lattice provides a linear dispersion relation where the Fermi velocity replaces the role of the speed of light in the usual Dirac Fermion spectrum. Recent experimental studies reveal that such unconventional electronic structure in graphitic carbon leads to unique electronic transport phenomena in 1‐dimensional carbon nanotubes and 2‐dimensional graphene. Combined with semiconductor device fabrication techniques and the development of new methods of nanoscaled material synthesis/manipulation enables us to investigate mesoscopic transport phenomena in these materials. The exotic quantum transport behavior discovered in these materials, such as room temperature ballistic transport, unusual half‐integer quantum Hall effect, and a non‐zero Berrys phase in magneto‐oscillations will be discussed in the connection to Dirac Fermion description in graphitic systems. (© 2006 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
Length separation studies of single walled carbon nanotube dispersions
Authors: Arnold K. , Hennrich F. , Krupke R. , Lebedkin S. , Kappes M. M. 
Published: September 2006

AbstractIn this contribution we present detailed studies of single walled carbon nanotubes (SWNTs) in water surfactant dispersions separated by size exclusion chromatography. We investigated length separated SWNT fractions by AFM, absorption spectroscopy and near‐infrared photoluminescence mapping. The ultrasonic induced scission process can be observed by AFM. (© 2006 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
Force spectroscopy measurements of MoSIx nanowires with functionalized molecules
Authors: Ploscaru M. , Kokalj Sasa Jenko , Uplaznik M. , Vengust D. , Turk D. , Mihailovic D. 
Published: September 2006

AbstractWe report a simple method of functionalization of MoSIx nanowires with biomaterials via the thiol group. We succeed to immobilize iodinated and sulphated high molecular mass thyroglobulin proteins on MoSIx nanowires. By controlling the preparation of the nanowires before self‐assembly we can attach proteins either at the ends or achieve complete wrapping of the nanowires. The control parameter is the S and I stoichiometry ratio of the MoSIx nanowires. Breaking force measurements were performed in order to confirm and characterise the wrapping of the nanowires with the proteins. (© 2006 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
Investigations of mechanism of carbon nanotube growth
Authors: Nasibulin A. G. , Pikhitsa P. V. , Queipo P. , Choi M. , Kauppinen E. I. 
Published: September 2006

AbstractStudies on the formation of single‐walled carbon nanotubes by an aerosol method based on the introduction of pre‐formed catalyst particles into conditions leading to carbon nanotube synthesis are presented. Carbon monoxide and iron nanoparticles were used as carbon source and catalyst, respectively. The carbon nanotube growth was found to occur at a temperature of around 900 °C in the heating section of the reactor with a growth rate exceeding 1.1 µm/s. A detailed analysis of possible processes during carbon nanotube formation revealed heptagon transformation as a limiting stage. A mechanism for carbon nanotube formation on the basis of the geometrical consideration was proposed. (© 2006 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
Uniaxial stress study of the Cu–H complex in ZnO
Authors: Lavrov E. V. , Weber J. 
Published: September 2006

AbstractThe cover picture of the current issue refers to the article by Lavrov and Weber which was selected as Editor's Choice [1]. The picture shows a microscopic model of the Cu–H complex investigated in the paper. The complex consists of a substitutional Cu atom at the Zn site with an H atom located between nearby O and Cu in the basal plane of the ZnO lattice. The atoms are shown in different colors: yellow for copper, red for hydrogen, cyan for oxygen, and grey for zinc. Hydrogen forms a strong bond with the O atom which gives rise to a local vibrational mode at 3192 cm–1 investigated in the paper under uniaxial stress. The c‐axis is parallel to the Cu–O bond pointing to the top of the figure.The authors work at the Institute of Applied Physics/Semiconductor Physics, TU Dresden, Germany.