bluuebunny/crossref_metadata_2025_split huggingface dataset:
Bimanes. 19. Characteristics of the molecular structures of 1,5‐diazabicyclo[3.3.0]octadienediones (9,10‐dioxabimanes) determined by x‐ray crystallography
Authors: Goldberg Israel , Bernstein Joel , Kosower Edward M. , Goldstein Ehud , Pazhenchevsky Barak 
Published: March 2009

AbstractThe molecular structures of a variety of 1, 5‐diazabicyclo[3.3.0]octadienediones (9, 10‐dioxabimanes), including three 9, 10‐dioxa‐syn‐bimanes, three 4, 6‐bridged 9, 10‐dioxa‐syn‐bimanes, and three 9, 10‐dioxa‐anti‐bimanes, as determined by x‐ray crystallography, are analyzed and compared with respect to planarity, bond distances, bond angles and intermolecular packing. “Planarity” may be the resultant of two non‐planar equilibrium forms, a conclusion based on the anisotropic thermal motion parameters of the central N‐N bond. “Amide”‐type conjugation (N‐C=O) is important in all planar bimanes; peripheral conjugation (N‐C=C‐C = O) is more significant in planar syn‐bimanes and decreased conjugation is evident in the bent bridged syn‐bimanes. Weak CH…O bonds contribute significantly to the crystal packing arrangements.
Herstellung und reaktivität von alkoxy‐1‐azafulvenen
Authors: Stachel Hans‐Dietrich , Poschenrieder Hermann , Immerz‐Winkler Elisabeth 
Published: March 2009

AbstractDie Titelverbindungen 7‐9 reagieren mit Nucleophilen an der Lactimethergruppe, während bei 6 Umsetzungen in 4‐Stellung, bei der bromierten Verbindung 14 in 4‐ wie auch in 6‐Stellung möglich sind.
2‐Acyloxypyrazines. Convenient acylating agents for amines
Authors: Ohta Akihiro , Shimazaki Makoto , Tamamura Hideo , Mamiya Yukari , Watanabe Tokuhiro 
Published: March 2009

Abstract2‐Acyloxypyrazines were found to be useful acylating reagents for amines. The preference of the acylation was for primary amines rather than secondary ones and also for aliphatic amines rather than aromatic ones.
Preparation of hexa‐, penta‐ and tetraphenyl‐2,6‐ and ‐2,7‐naphthyridines
Authors: Mataka Shuntaro , Takahashi Kazufumi , Tashiro Masashi 
Published: March 2009

AbstractDi‐ and triphenyldibenzoylpyridines (1) were prepared by the condensation reaction of 3, 4‐dibenzoyl‐2, 5‐diphenylthiophene (2) with methylamine derivatives 3 and by the subsequent oxidative ring cleavage of the resultant thieno[3, 4‐c]pyridines 4. The reaction of 1 with 3 afforded polyphenyl‐2, 6‐ (5) and ‐2, 7‐naphthyridines (6).
Structure of hexacyclen salts 1,4,7,10,13,16‐hexaazacyclooctadecanehexahydrogennitratemonohydrte
Authors: Margulis T. N. , Zompa L. J. 
Published: March 2009

AbstractThe crystal structure of the anion‐complexing agent, 1, 4, 7, 10, 13, 16‐hexaazacyclooctadecanehexahydrogen‐nitratemonohydrate, has been determined by a single‐crystal x‐ray diffraction study. Nitrate and water are bound strongly to the hexacyclen ring by hydrogen‐bonds and ion‐ion interactions. The hexacyclen ring has a conformation which is relatively independent of its crystallographic environment.
Synthesis and acylating properties of 4,5‐dihydro‐6H‐1,3,4‐ oxadiazin‐6‐ones
Authors: Farina Carlo , Pifferi Giorgio , Nasi Ferdinando , Pinza Mario 
Published: March 2009

AbstractCyclization of α‐acylhydrazinoacids with dicyclohexylcarbodiimide or with acetic anhydride allows an easy entry to the little known class of 4, 5‐dihydro‐6H‐1, 3, 4‐oxadiazin‐6‐ones. Such compounds maintain the optical activity of the starting hydrazino acids and may be exploited as useful acylating agents.
Synthesis and spectral properties of the 1‐aryl‐2‐phenyl‐4‐oxo‐4,5,6,7‐tetrahydroindole oximes and of their beckmann rearrangement products
Authors: Dagher C. , Hanna R. , Terentiev P. B. , Boundel Y. G. , Maksimov B. I. , Kulikov N. S. 
Published: March 2009

AbstractUnder Beckmann conditions the oximes of the 1‐aryl‐2‐phenyl‐4‐oxo‐4,5,6,7‐tetrahydroindoles 2a‐k are rearranged yielding as the sole product, 1‐aryl‐2‐phenyl‐4‐oxo‐1,4,5,6,7,8‐hexahydropyrrolo[3,2‐c]azepine 3a‐k. The spectral data (ir, uv, ms) of these two classes of compounds are also discussed.
Synthesis of some 1‐hydroxy derivatives of 4‐ and 6‐azaindole analogues
Authors: Daisley Roy W. , Hanbali Jafar R. 
Published: March 2009

Abstract1‐Hydroxy‐4‐azaindole and 1‐hydroxy‐4‐(and 6)‐azaindol‐2(3H)‐one derivatives are novel compounds and a facile synthesis by the reductive cyclisation of substituted 3‐nitropyridines is described. Problems associated with the catalytic hydrogenation of the parent nitro compounds are also discussed.
Unequivocal synthesis of 2,3,6‐triazaphenothiazine and two new tetraazaphenothiazine heterocycles
Authors: Okafor Charles O. , Castle Raymond N. , Wise Dean S. 
Published: March 2009

AbstractThis paper describes the unequivocal synthesis of three new heterocycles: 2, 3, 6‐triazaphenothiazine (7) and 2, 3, 6, 9‐tetraazaphenothiazine (18), both parents of the respective ring systems and the 6, 8‐dihydro‐7, 9‐di‐oxo derivative of 2, 3, 6, 8‐tetrahydrophenothiazine (12). These compounds were obtained by base‐catalysed condensation of 4, 5‐dichloropyridazine (8) with the appropriate o‐amino‐heterocyclic thiols 9, 11, 16. In contrast, reaction of 2, 3, 5‐trichloropyrazine (20) with 4, 6‐diaminopyrimidine‐5‐thiol (21) and 2‐amino‐6‐picoline‐3‐thiol (28) gave 5‐chloro‐2, 3‐bis(diaminopyrimidinyl‐5‐thio)pyrazine (33) and 5‐chloro‐2, 3‐bis(2‐amino‐6‐picolinyl‐3‐thio)pyrazine (29), respectively. Chloropyrazine (34) and 3‐aminopyridine‐2(1H)‐thione (9) followed the latter reaction path to 2‐(3‐amino‐2‐pyridyl) pyrazinyl sulfide (35) in good yields. Structural assignments were based on their infrared, ultraviolet, nmr and mass spectra.
The synthesis of four isomeric bisthienothiepinones
Authors: Charonnat Jeffrey A. , Muchowski Joseph M. , Nelson Peter H. 
Published: March 2009

AbstractThe displacement reaction between sodium thiophene‐3‐thiolate and methyl 3‐(bromomethyl)thiophene‐2‐carboxylate (5) gave the expected thioether 7a. Basic hydrolysis afforded the carboxylic acid 7b; conversion to the acid chloride, and treatment of the latter with stannic chloride then produced the bisthienothiepinone 1. Using analogous reactions the isomers 2‐4 were also synthesized.
Reactions of 4‐cyano‐ and 4‐methylimidazoles with isocyanates
Authors: Mitsuhashi Keiryo , Itho Ei‐Ichi , Kawahara Takeo , Tanaka Kiyoshi 
Published: March 2009

Abstract4‐Cyano‐ and 4‐methylimidazoles reacted with methyl and aryl isocyanates to give exclusively 1‐(substituted carbamoyl)‐4‐cyano‐ and 4‐methylimidazoles, respectively. Refluxing of 1‐carbamoyl‐4‐methylimidazoles in nitrobenzene yielded 2‐carbamoyl‐4‐methylimidazoles through a known migration, whereas the 4‐cyano analogues could not be caused to migrate. On the other hand, the treatment of 4‐cyano‐1‐(methylcarbamoyl)imidazole with methyl isocyanate under the basic conditions resulted in the formation of 2‐methyl‐1‐(methylcarbamoylimino)‐2, 3‐dihydro‐1H‐imidazo[1, 5‐c]imidazol‐3‐one which must be formed via the migration of the carbamoyl group to another nitrogen followed by the intramolecular cyclization of the newly introduced carbamoyl group with its viccyano group.
Studies on the synthesis of heterocyclic compounds. Part X. One‐step route to 1,2‐dimethyl‐3‐R‐5‐salicyloylimino‐3‐pyrazolines
Authors: Plescia Salvatore , Daidone Giuseppe 
Published: March 2009

AbstractThis communication outlines the development of a direct synthetic route to 1,2‐dimethyl‐3‐R‐5‐salicyloyl‐imino‐3‐pyrazolines, starting from readily available 3(5)‐aminopyrazoles 1a, b, c and methyl salicylate. The structures of the new compounds 3a, b, c were determined on the basis of analytical and spectroscopic data as well as on the acid hydrolysis products.
Synthesis, structure elucidation and antibacterial activity of 6‐ethyl‐6,9‐dihydro‐9‐oxopyrazolo[3,4‐f]quinoline‐8‐carboxylic acid
Authors: Schwan Thomas J. , Freedman Raymond , Pollack Jay R. 
Published: March 2009

AbstractThe preparation, structure elucidation and antibacterial activity of 6‐ethyl‐6,9‐dihydro‐9‐oxopyrazolo‐[3,4‐f]quinoline‐8‐carboxylic acid are reported.
Synthesis of 5‐Aryl‐3‐(4‐pyridyl)‐1,2,4‐oxadiazoles
Authors: Braña Miguel F. , Castellano José M. , Yunta Maria J. R. 
Published: March 2009

AbstractThe title oxadiazoles were formed in the reaction of N‐(4‐pyridylmethyl)arylamides with nitrosyl chloride in low yields.
Reductive cleavage of ether and thioether bonds on 1,3‐benzodioxole and 1,3‐benzoxathiole derivatives
Authors: Melis Stefana , Sotgiu Francesca , Piras Pier Paolo , Plumitallo Antonio 
Published: March 2009

AbstractThe reaction of lithium and sodium diethylamide with 1,3‐benzodioxoles and 1,3‐benzoxathioles is here reported. 1,3‐Benzodioxoles exhibit selective cleavage of the ether bond with formation of alkoxyphenols; 1,3‐benzoxathioles when reacting with sodium diethylamide lead to 2‐alkoxybenzenethiols while with lithium diethylamide give 2‐alkoxybenzenethiols together with 2‐(alkylthio)phenols.
Synthesis of some 4‐substituted‐2‐(o‐halogenophenyl)‐1,2,3‐triazoles
Authors: Swartz David L. , Karash Angela R. , Berry Laura A. , Jaeger David L. 
Published: March 2009

AbstractMesoaldehyde 1,3‐dioxime was treated with either 2,4,6‐trichlorophenyl‐ (a), o‐fluorophenyl‐ (b), or o‐bromophenyl‐ (c) hydrazine to give the corresponding mesoaldehyde 1,3‐dioxime‐2‐halogenophenylhydrazones (1a,b,c). The latter were O‐acetylated with acetic anhydride, and cyclized to triazole 4‐oximes (3b, c) or triazole 4‐O‐acetyloximes (6a,b,c) with cesium carbonate, then converted to nitriles (7a,b,c) by refluxing with acetic anhydride followed by pyrolysis, or to aldehydes (4a,b,c) by hydrolysis. The nitriles (7a,b,c) were also converted to acids (9a,b,c), esters (10a,b,c), amides (8a,c), an alcohol (11a), and an amine (12a). In addition, tetrazoles of two types were prepared. The first (13d,e) were obtained from the acid chlorides by the action of 5‐aminotetrazole, whereas the second (14f) was produced from the respective nitrile by the action of ammonium azide.
Kinetic study on the acid hydrolysis of 1‐aryl‐2‐phenyl‐2‐imidazolines. Basicity‐rate of hydrolysis and structure relationships
Authors: Fernández Beatriz M. , Reverdito Ana M. , Perillo Isabel A. , Lamdan Samuel 
Published: March 2009

AbstractRate constants (kobs) of hydrolysis in sulfuric acid‐water mixtures at 100° for five 1‐aryl‐2‐phenyl‐2‐imidazolines were determined. The influence of substituents in the phenyl group at N‐1 upon the rate of hydrolysis was studied. When the imidazoline ring is considered to be a substituent of the benzene ring at N‐1, a good correlation with the Hammett equation is found.In opposition to the behavior in alkaline media it was observed that reaction rates were enhanced by electron‐withdrawing phenyl substituents and reduced by electron‐releasing groups providing, similarly, a change in the mechanism of the reaction in the second case that was not observed in the first. Agreement with the Hammett equation allowed comparison between experimental and “calculated” rate constants which are fairly close. An equation relating the rate constants with the pKa values of the imidazolinium ions is given.
Reaction between ethyl ω‐chloroalkylimidates and hydrazides
Authors: Bonanomi Michele , Baiocchi Leandro 
Published: March 2009

AbstractIt is already known that ethyl ω‐chloroalkylimidate hydrochlorides and aroyl hydrazides gave, when reacted together in boiling ethanol, 2‐aryl‐5‐ω‐haloalkyl‐1,3,4‐oxadiazoles. It has now been found that the reaction follows a different course in the presence of triethylamine. In particular, 2‐aryl‐5,6,7,8‐tetrahydro‐1,2,4‐triazolo[5,1‐α]pyridines were obtained from ethyl δ‐chlorovalerimidate, whereas N‐aroylaminoimino‐pyrrolidines are the products obtained from ethyl γ‐chlorobutyrimidate. A similar case, in which the closure of the triazole ring to obtain a dihydropyrrolotriazole was found to be more difficult than the corresponding closure to a tetrahydrotriazolopyridine, is described. Also the reaction between the imidates and carbethoxy‐hydrazine, which gives piperidine and pyrrolidine derivatives, is reported.
Reaction of 1,1′‐iminobis‐2‐butanols with sulfuric acid
Authors: Hernestam Sven 
Published: March 2009

AbstractTreatment of 1,1′‐iminobis‐2‐butanols with 70% w/w sulfuric acid gives cis‐ and trans‐2,6‐diethylmorpholines, 3‐ethyl‐4‐methylpyridine and unsaturated 3‐ethyl‐4‐methylpiperidines. Hydrogenation of the unsaturated 3‐ethyl‐4‐methylpiperidines gives cis‐ and trans‐3‐ethyl‐4‐methylpiperidines. With 50% w/w sulfuric acid cis‐ and trans‐2,6‐diethylmorpholines and a small amount of cis‐ and trans‐2‐ethyl‐7‐methyl‐hexahydro‐1,4‐oxazepines are obtained.
Deoxygenation of quinoxaline and phenazine N‐oxides by catalytic transfer reduction and by iodide in the presence of pyridine/sulfur trioxide complex
Authors: Demirdji S. H. , Haddadin M. J. , Issidorides C. H. 
Published: March 2009

AbstractQuinoxaline and phenazine di‐N‐oxides are deoxygenated under mild conditions by catalytic transfer reduction or by treatment with sodium iodide in the presence of pyridine/sulfur trioxide complex.
Preparation of phenylquinoxaline from α,α‐diaminoketones and dimethyl‐O‐phenylenediamine
Authors: Saeed Ali A. H. , Ebraheem Ebraheem K. 
Published: March 2009

AbstractAmination of α,α‐diaminoketones 1 by 4,5‐dimethyl‐o‐phenylenediamine gave 6,7‐dimethyl‐2‐phenylquinoxaline (II) in a high yield. The reaction may occur through formation of α‐ketoazomethine III. The α,α‐di‐aminoketones were obtained by condensation of phenylglyoxal and substituted anilines.
Pyridazines. XXVI. A novel synthesis of pyrano[2,3‐d]pyridazines
Authors: Heinisch Gottfried , Holzer Wolfgang , Nawwar Galal A. M. 
Published: March 2009

AbstractA novel approach to the title ring system starting with conveniently available cinnamoylacetonitrile (1) is proposed. It involves the Japp‐Klingemann reaction of 1 followed by thermally induced cyclisation of hydrazones 2 and subsequent addition of the resulting pyridazine derivatives 3 to 2‐substituted cinnamonitriles 4a, 4b. The structures of the pyrano[2,3‐d]pyridazines 5a, 5b, thus obtained, were established on basis of spectroscopic data.
Synthesis of 3‐substituted‐4‐methyl‐5‐acetyl‐4‐thiazoline‐2‐thione
Authors: D'Amico John J. , Bollinger Frederic G. , Freeman John J. 
Published: March 2009

AbstractThe reaction of various potassium salts [RNHC(=S)SK, R = N(CH3)2, morpholino, piperidino, and hexahydro‐1‐(1H)‐azepinyl] with 3‐chloro‐2,4‐pentanedione in ethanol at 25–30° afforded the 1‐acetylacetonyl substitutedaminodithiocarbamates 1–4 [RNHC(=S)SCH(COCH3)2]. Under refluxing conditions, the same reactants gave the heterocyclic compounds 5–8. Possible mechanism and supporting ir, nmr and mass spectral data are discussed.
Synthesis of 3a,4,5,6,7a‐Hexahydro‐3a‐hydroxy‐3‐substitutedamino‐2‐benzothiazolinethiones and Related Compounds
Authors: D'Amico John J. , Bollinger Frederic G. , Freeman John J. , Dahl William E. 
Published: March 2009

AbstractThe reaction of various potassium or ammonium salts [RNHC(=S)SM, M = K or NH4; R = N(CH3)2, morpholino, pyrrolidino, piperidino, and hexahydro‐1‐(1H)‐acepinyl] with 2‐chlorocyclohexanone in alcohol at 25–30° afforded the title compounds 1 and 3–6. The treatment of these compounds with a catalytic amount of p‐toluenesulfonic acid in refluxing benzene furnished the dehydrated products 2 and 7–10. The reaction of potassium dithiocarbazate with 2‐chlorocyclohexanone or 3‐chloro‐3,4‐pentanedione in refluxing ethanol afforded 11, a six membered heterocycle and 12, a five membered heterocycle, respectively. Possible mechanisms and supporting nmr, ir, uv mass spectral data are discussed.
Mechanistic observations in the gewald syntheses of 2‐aminothiophenes
Authors: Peet Norton P. , Sunder Shyam , Barbuch Robert J. , Vinogradoff Anna P. 
Published: March 2009

AbstractThe Gewald syntheses were employed to prepare a series of 2‐amino‐3‐carboethoxythiophenes, and the syntheses of two of these, namely, the 3,4‐trimethylene (1f) and 3,4‐tetramethylene (1g) derivatives, were examined in detail. In two preparations of1f, octahydro‐6a‐(4‐morpholinyl)‐2‐thioxocyclopenta[b]pyrrole‐3‐carboxylic acid (7) was a co‐product. The structure of7was ascertained from its 300 MHz1H nmr and13C nmr spectra, and by its conversion to 1,4,5,6‐tetrahydro‐2‐mercaptocyclopenta[b]pyrrole‐3‐carboxylic acid ethyl ester (8). Isolation of7and other observations led to postulated mechanisms for three of the Gewald thiophene syntheses.
Heterocycles. Part VIII. Synthesis of new substituted benz[g]indazoles
Authors: El‐Rayyes N. R. , Al‐Jawhary A. 
Published: March 2009

AbstractAryl aldehydes I reacted with α‐tetralone to give the corresponding 2‐arylidene‐1‐tetralone II. Condensation of the latter chalcones with hydrazine, methylhydrazine and phenylhydrazine produced the corresponding benzo[g]indazoles III, V and VI respectively. Acetylation of the 2H‐benz[g]indazole derivatives III gave the corresponding 2‐acetylated compounds IV. The structure of all products was elucidated by chemical and spectroscopic methods.
An unexpected product from the cyclodesulfurization of 5‐[1‐(3‐methoxycarbonyl)thioureido]‐1‐(β‐D‐ribofuranosyl)imidazole‐4‐ carboxamide with dicyclohexylcarbodiimide
Authors: Chern Ji‐Wang , Groziak Michael P. , Townsend Leroy B. 
Published: March 2009

AbstractThe treatment of 5‐[1‐(3‐methoxycarbonyl)thioureido]‐1‐(β‐D‐ribofuranosyl)imidazole‐4‐carboxamide with N,N'‐dicyclohexylcarbodiimide in N,N‐dimethylformamide has afforded 4‐cyano‐5‐[1‐(3‐methoxycarbonyl)‐ureido]‐1‐(β‐D‐ribofuranosyl)imidazole.
Substituted γ‐Lactones. 35. Reduction of 4‐aroyl‐3‐hydroxy‐2(5H)‐furanones
Authors: Zimmer Hans , Manning M. J. , Ventura M. , Amer Adel , El Massry Abdel Monem 
Published: March 2009

AbstractThe reduction of 4‐aroyl‐3‐hydroxy‐2(5H)‐furanons 1a‐c was investigated using different reducing agents. Sodium borohydride reacts with type 1 compounds by loss of water to yield 4‐(arylmethylene)‐2,3(4H,5H)‐furandiones 2a‐c. Platinum or charcoal supported by pallodium chloride transforms 1a to 4‐benzyl‐3‐hydroxy‐2(5H)‐furanone (3). Compounds 2a and 2b react with o‐phenylenediamine to give 3‐(E‐(1′‐hydroxymethyl‐2′‐aryl)ethenyl]‐2‐quinoxalinones 4a and 4b. The lactone 3 under the same conditions splits out formaldehyde and forms 3‐(2′‐phenylethyl)‐2‐quinoxalinone (6). The structure assignments of the novel compounds are based on elemental analysis and nmr as well as ir spectroscopic data.
Synthesis of 8‐methylpyrido[2,3‐d:6,5‐d'x]dipyrimidine‐2,4,6(3H,10H,7H)‐triones and their use in the oxidation of alcohols
Authors: Moriyama Kenji , Nagamatsu Tomohisa , Yoneda Fumio 
Published: March 2009

AbstractA new‐type pyridodipyrimide, 8‐methylpyrido[2,3‐d:6,5‐d']dipyrimidine‐2,4,6(3H,10H,7H)‐triones were prepared by the condensation of 6‐alkyl‐ or 6‐aryl‐amino‐2‐methylpyrimidin‐4(3H)‐ones with 2,4,6‐trichloropyrimidine‐5‐carbaldehyde or 3‐alkyl‐6‐chloro‐5‐formyluracils. The pyridodipyrimidines thus obtained oxidized alcohols under neutral conditions to yield the corresponding carbonyl compounds and a significant autorecycling in the oxidation was observed.
Studies on pyrrolidinones. A convenient synthesis of 2‐methyl‐5‐(5‐oxo‐1‐benzyl‐2‐pyrrolidinyl)‐1,3,4‐oxadiazole
Authors: Rigo Benoǐt , Couturier Daniel 
Published: March 2009

Abstract2‐Methyl‐5‐(5‐oxo‐1‐benzyl‐2‐pyrrolidinyl)‐1,3,4‐oxadiazole is easily obtained by dehydration of N‐acetyl‐1‐benzylpyroglutamic acid hydrazide with a methanesulfonic acid/phosphoric anhydride mixture.
Furopyridines. III. A new synthesis of furo[3,2‐b]pyridine
Authors: Shiotani Shunsaku , Morita Hiroyuki 
Published: March 2009

AbstractA convenient synthesis of furo[3,2‐b]pyridine and its 2‐ and 3‐methyl derivatives from ethyl 3‐hydroxypiconate (1) is described. The hydroxy ester1wasO‐alkylated with ethyl bromoacetate or ethyl 2‐bromopropionate to give the diester2aor2b. Cyclization of compound2aafforded ethyl 3‐hydroxyfuro[3,2‐b]pyridine‐2‐carboxylate (3) which in turn was hydrolyzed and decarboxylated to give furo[3,2‐b]pyridin‐3‐(2H)‐one (4a). Cyclization of2bgave the 2‐methyl derivative4b. Reduction of4aand4bwith sodium borohydride yielded the corresponding hydroxy derivative5aand5brespectively, which were dehydrated with phosphoric acid to give furo[3,2‐b]pyridine (6a) and its 2‐methyl derivative (6b). 2‐Acetylpyridin‐3‐ol (8) was converted to the ethoxycarbonylmethyl ether (9) byO‐alkylation with ethyl bromoacetate, which was cyclized to give 3‐methylfuro[3,2‐b]pyridine‐2‐carboxylic acid (10). Decarboxylation of10afforded 3‐methylfuro[3,2‐b]pyridine (11).
Studies on the constituents of bocconia cordata. III Structure elucidation of bocconine by means of nuclear magnetic resonance spectroscopic studies
Authors: Konda Yaeko , Harigaya Yoshihiro , Onda Masayuki 
Published: March 2009

AbstractThe nmr spectroscopic studies on methoxybocconine are described. The spectral data indicate bocconine to be 2,3,7,8‐bis(methylenedioxy)‐10‐methoxy‐5‐methylbenzo[c]phenanthridine.
New syntheses of per‐N‐alkyl‐substituted triaza‐ and tetraaza‐crovm compounds containing an allyloxymethyl substituent
Authors: Krakowiak Krzysztof E. , Bradshaw Jerald S. , Forsnes Evan V. , Izatt Reed M. 
Published: March 2009

AbstractSeven new per‐N‐alkyl‐substituted triaza‐ and tetraaza‐crovm compounds have been prepared using commercially available or easily synthesized per‐N‐alkyl‐substituted oligoethylene and oligopropylene polyamines, tetraazapentaethylene and tetraazaheptaethylene glycols. Five of these new polyaza‐crowns have a pendant allyloxymethyl substituent.
Crossed bisadducts in the reaction of pyridine with two different nitrile oxides
Authors: Albini Franca Marinone , De Franco Rita , Bandiera Tiziano , Caramella Pierluigi , Corsaro Antonino , Perrini Giancarlo 
Published: March 2009

AbstractBisadducts of some aromatic nitrile oxides to pyridine are described. Crossed adducts are formed by exposure of pyridine to a couple of different nitrile oxides.
Synthesis of nitrogen‐containing heterocycles. 4. A facile route to new 1, 2, 4‐triazole derivatives
Authors: Miyamoto Yoshiko , Yamazaki Chiji 
Published: March 2009

AbstractThe reaction of amino‐N(4),N(4)‐dimethylaminornethylenehydrazones 1 of some aliphatic carbonyl compounds with ethyl ethoxymethylenecyanoacetate 2 gave directly symmetrical gem‐bis(3‐dimethylamino‐1, 2, 4‐triazol‐1‐yl)alkanes 4 and (3‐dimethylamino‐1, 2, 4‐triazol‐1‐yl)alkenes 5 at room temperature, with the former being major product. On the other hand, the reaction of amino‐N(4)‐methylaminomethylenehydrazone homologue 1 of aliphatic ketone with 2 gave ethyl 2‐alkyl‐5‐methylamino[1, 2, 4]triazolo[1, 5‐c]pyrimidine‐8‐carboxylate 7 as the only product with elimination of alkane.
Methyl 2‐benzoylamino‐3‐dimethylaminopropenoate in the synthesis of heterocyclic systems. An attempt to prepare benzoylamino substituted azolo‐ and azinopyrimidines with a bridgehead nitrogen atom
Authors: Stanovnik Branko , Van De Bovenkamp Henry , Svete Jurij , Hvala AleŠ , Simoni č Igor , Tišler Miha 
Published: March 2009

AbstractMethyl 2‐benzoylamino‐3‐dimethylaminopropenoate (2) was introduced as a new reagent for the preparation of fused pyrimidinones 4 from heterocyclic α‐amino compounds in acetic acid. In this manner, derivatives of pyrido[1,2‐a]pyrimidine 4a,b,f, pyrimido[1,2‐b]pyridazine 4g, pyrimido[1,2‐c]pyrimidine 4j, pyrazino[1,2‐a]pyrimidine 4k, thiazolo[2,3‐b]pyrimidine 41, pyrazolo[1,5‐a]pyrimidine 4m, and 1,2,4‐triazolo‐[1,5‐a]pyrimidine 4n were prepared.
Synthesis and spectra of 12‐(o‐ and p‐R‐phenyl)‐9,9‐dimethyl‐7,8,9,10,11,12‐hexahydro and 8,9,10,11‐tetrahydrobenz[a]acridin‐11‐ones. Structure correction of 1,2,3,4,5,6‐hexahydro and 1,2,3,4‐tetrahydro‐2,2‐dimethyl‐5‐aryl‐6‐aza‐9,10‐benzophenanthren‐4‐ones. II
Authors: Martínez Roberto , Cortés Eduardo , Toscano R. Alfredo , Linzaga Irma 
Published: March 2009

AbstractIt has been reported that the reaction of β‐naphthylamine, dimedone and the appropriate aromatic aldehyde in ethanol gave 1,2,3,4,5,6‐hexahydro‐2,2‐dimethyl‐5‐aryl‐6‐aza‐9,10‐benzophenanthren‐4‐ones, III, which upon treatment with chromic anhydride, yielded the corresponding tetrahydro derivatives, IV. However, the attempted preparation of these compounds resulted instead of the formation of isomeric acridin‐11‐ones, V and VI. Structures were confirmed by ir, 1H nmr, ms and X‐ray spectroscopy.