bluuebunny/crossref_metadata_2025_split huggingface dataset:
Maîtriser le temps pour un jeune prince : le Rosier des guerres de Pierre Choinet, commandé par Louis XI pour le futur Charles VIII
Authors: Scordia Lydwine 
Published: March 2024

En raison d’errements sur son contenu et son auteur, le Rosier des guerres n’a jamais été édité. Pour évaluer l’intérêt de ce traité commandé par Louis XI à son médecin et astrologue, le Normand Pierre Choinet, il convient de recourir aux douze témoins manuscrits. Une chronique historique, ourlée d’une centaine de manchettes astrologiques en latin, occupe 80 % de cet art de gouverner : histoire et astrologie ont été conçues pour délivrer des leçons politiques permettant au futur Charles VIII de l’emporter sur ses ennemis.
La Briev estoire del navigaige mounsire Jehan Prunaut en Afrique : forgerie du XVIIe siècle ou témoignage d’un texte médiéval ?
Authors: Maneuvrier Christophe , Vielliard Françoise 
Published: March 2024

La Briev estoire del navigaige mounsire Jehan Prunaut, roenois, en la tiere des noirs homes publiée par Pierre Margry en 1867 dans le contexte de la rivalité des nations européennes pour s’imposer sur le continent africain est depuis la fin du XIXe siècle considérée comme une forgerie. La découverte de la copie manuscrite de Lucien de Rosny qui a servi de base à l’édition Margry permet de rouvrir le dossier, de soumettre le texte à un examen critique et d’en réexaminer les données en en recherchant les traces dans les récits de voyage postérieurs. Il en ressort une présomption d’authenticité au moins pour la première partie du texte qui témoigne que des marins normands ont pu atteindre les côtes du Sénégal à la fin du XIVe siècle.
Du corps malade au corps écrit dans Les Corps conducteurs, Le Jardin des Plantes et Le Tramway
Authors: Genin Christine 
Published: March 2024

L’expérience par Claude Simon de la maladie n’a pas été très souvent étudiée. L’écriture du corps malade est pourtant un motif récurrent des textes simoniens. Dans les trois romans où l’expérience de la maladie est la plus subjective, Les Corps conducteurs, Le Jardin des Plantes et Le Tramway, c’est le texte tout entier qui devient un grand corps malade, un « corps sans organes », d’autant plus vivant qu’il est brassé, bouleversé, disséminé et recomposé par le flux de la souffrance et de la mort.
National Athletic Trainers’ Association Bridge Statement: Management of Sport-Related Concussion
Authors: Broglio Steven P. , Register-Mihalik Johna K. , Guskiewicz Kevin M. , Leddy John J. , Merriman Alejandra , Valovich McLeod Tamara C. 
Published: March 2024

ObjectiveTo provide athletic trainers and team physicians with updated recommendations to the 2014 National Athletic Trainers’ Association (NATA) concussion position statement regarding concussion management, specifically in the areas of education, assessment, prognostic factors, mental health, return to academics, physical activity, rest, treatment, and return to sport.BackgroundAthletic trainers have benefited from the 2 previous NATA position statements on concussion management, and although the most recent NATA position statement is a decade old, knowledge gains in the medical literature warrant updating several (but not all) recommendations. Furthermore, in various areas of the body of literature, current evidence now exists to address items not adequately addressed in the 2014 statement, necessitating the new recommendations. This document therefore serves as a bridge from the 2014 position statement to the current state of concussion evidence, recommendations from other organizations, and discrepancies between policy and practice.RecommendationsThese recommendations are intended to update the state of the evidence concerning the management of patients with sport-related concussion, specifically in the areas of education; assessment advances; prognostic recovery indicators; mental health considerations; academic considerations; and exercise, activity, and rehabilitation management strategies.
Computational design, docking, and molecular dynamics simulation study of RNA helicase inhibitors of dengue virus
Authors: Satpathy Raghunath , Acharya Sonali , Behera Rashmiranjan 
Published: March 2024

Background & objectives:
RNA viruses are complex pathogens in terms of their genetic makeup, mutation frequency, and transmission modes. They contain the RNA helicase enzyme, which plays a crucial role in the viral genome replication process. This work aims to develop and screen a potential molecule that could function as a dengue virus (DENV) RNA helicase inhibitor.

Methods:
The present study was performed by taking 26 potential derivatives of gedunin phytochemicals from the PubChem database as ligands. The binding of the compounds was analyzed by in silico docking considering DENV RNA helicase enzyme as the receptor.

Results:
After a thorough analysis of the docking scores, toxicity, and physicochemical properties, the compound tetrahydrogedunin was obtained as the best. Based on tetrahydrogedunin molecular structure, 100 drug-like molecules were designed using the Data Warrior tool. After screening for drug-likeness and ADMET properties, derivative number 42 was considered as promising. Further comparative docking of derivative 42 and a standard inhibitor molecule ST-610 with DENV RNA helicase enzyme showed binding affinity of 10.0 kcal/mol and -9.6 kcal/mol, respectively. The favorable interaction between DENV RNA helicase and derivative 42 was further validated by 50 nanoseconds molecular dynamics simulation and MM-GBSA analysis.

Interpretation & conclusion:
Since the antiviral activity of derivative 42 has not been reported till date, the compound was predicted as a novel therapeutic molecule that can act against the dengue virus (DENV) RNA helicase enzyme.
Asymmetrical reproductive interference between Aedes aegypti and Aedes albopictus: Implications for coexistence
Authors: Hasan Tanvir , Afrin Sadia , Sultana Afroza , Islam Ashekul 
Published: March 2024

Background & objectives:

Aedes aegypti and Ae. albopictus are two sympatric mosquito species that compete with each other for resources when their breeding habitats overlap. This study examines what happens when sympatric Ae. aegypti and Ae. albopictus mosquitoes’ mate with each other and other species by looking at insemination rates, fecundity, and hatchability rate.

Methods:
We performed controlled mating experiments in laboratory settings, assessing both conspecific and interspecific crosses. We measured insemination rates, egg numbers, and hatching success to examine the reproductive interference dynamics between these two distinct mosquito species.

Results:
In the context of conspecific mating, it was observed that both female Ae. aegypti and Ae. albopictus exhibited high insemination rates, with percentages 98% and 94%, respectively. However, interspecific mating exhibited interesting asymmetries as Ae. albopictus males achieved a notable insemination success rate of 28% when mating with Ae. aegypti females, while Ae. aegypti males achieved only an 8% insemination success with Ae. albopictus females. Additionally, females that mated with interspecific males had reduced production of viable eggs compared to conspecific mating. Most notably, interspecific mating resulted in the production of infertile eggs, while conspecific mating led to successful hatching.

Interpretation & conclusion:
The study reveals that Ae. aegypti and Ae. albopictus can asymmetrically interfere with each other’s reproduction, causing a ‘satyr’ effect. This understanding of interspecific competition and reproductive interference in these mosquito species could impact their coexistence in shared breeding habitats.
Outcome assessment of the implementation of Mass Drug Administration against lymphatic filariasis in Kalaburagi (Gulbarga) Karnataka, India: A cross-sectional survey
Authors: Babu Puttamaligaiah Subhas , Goud Bhoompuram Nagaraja , Kambale Shambhulinga B 
Published: March 2024

Background & objectives:
Mass Drug Administration (MDA) of Di-Ethyl Carbamazine and Albendazole is an effective strategy recommended by the World Health Organization to prevent transmission and eliminate lymphatic filariasis. Under the National Vector Borne Disease Control Programme (NVBDCP) in India, MDA is carried out as a yearly activity in endemic areas to accelerate the progress towards elimination of lymphatic filariasis. The study was carried with the objective to determine the coverage of MDA against lymphatic filariasis among the eligible population in Kalaburagi district, Karnataka and delineate the common reasons for non-acceptance of MDA.

Methods:
Field-based cross-sectional survey was carried out. Cluster sampling of 4 clusters (3 rural and 1 urban) from four different taluks (one cluster from each taluk) of the district reporting high, medium and low coverage of MDA (as reported by District Malaria Office) Members from selected households in all clusters were interviewed regarding MDA administration, directly observed treatment, side effects and any co morbidities which ruled out MDA administration. Responses documented as tally marks in assessment sheets shared by NVBDCP office. Proportions, frequencies, and mean were calculated and inferential statistics were used.

Results:
A total of 1263 individuals were assessed for MDA from a total 240 households (60 households in each cluster). The coverage of MDA varied from 90.33% in Heerapur in Kalaburagi Urban to 97.87% in Mogala thanda (Chittapur Taluk).

Interpretation & conclusion:
MDA Coverage against lymphatic filariasis has improved when compared to previous studies and it has also exceeded the coverage threshold as determined by programme for elimination of lymphatic filariasis.
Comparing the antimicrobial properties of graphene oxide silver nanoparticles as a root canal irrigant: A randomized controlled trial
Authors: Sevagaperumal Annapoorani , Lakshmi M. K. Gayathri , Piriyanga R. S. Rathna , Priyadharshini S. Swathi , Abirami A. Azhagu , Sherwood I. Anand 
Published: March 2024

Aim:
The current study aimed to compare and evaluate the antimicrobial efficacy of graphene oxide (GO) silver nanoparticle (AgNp) as root canal irrigant (RCI) with other RCIs in maxillary anterior teeth with necrotic pulp.

Methods:
The GO AgNp RCI was synthesized following modified Turkevich method and subsequent physicochemical characterization was carried out. Sample size was calculated to be 44 and divided into four groups. Following initiation of root canal treatment, preirrigation aerobic and anaerobic samples were collected in suitable medium and the same was done after completion of irrigation adapting the proposed protocol. Further, culture of aerobic and anaerobic samples was done accompanied by determination of bacterial viability count. From the obtained results, statistical analysis was performed and analysis of variance with post hoc was used to compare the antibacterial efficacy between the four irrigants.

Results:
The statistical analysis ended up with a significant difference in antibacterial properties between GO AgNps and normal saline, 2% chlorhexidine (P < 0.01) against both aerobic and anaerobic organisms. 2.5% sodium hypochlorite and GO AgNp irrigant showed a similar result against aerobic organisms (P = 1.00) while 2.5% sodium hypochlorite was slightly effective against anaerobic organisms (P = 0.83). The bacterial viability counts also showed results in accordance with culture results.

Conclusion:
From the above results, it can be concluded that the GO AgNp irrigant is an effective biocompatible antimicrobial agent, comparable to that of 2.5% sodium hypochlorite and superior to 2% chlorhexidine and normal saline.
Present and Future Use of Exosomes in Dermatology
Authors: De Abhishek , Chakraborty Disha , Agarwal Ishad , Sarda Aarti 
Published: March 2024

Abstract
Exposure to external environmental stimuli can lead to skin aging, pigmentation, hair loss, and various immune-mediated as well as connective tissue diseases. Although conventional treatments are routinely used and favoured, they fail to achieve an adequate balance between clinical and cosmetic outcomes. Exosomes are vesicles with a lipid bilayer released by several cell types. These bioactive vesicles play a crucial role in intercellular communication and in several other physiological and pathological processes. They serve as vehicles for bioactive substances including lipids, nucleic acids, and proteins, making them appealing as cell-free treatments. According to studies, exosomes play a vital role in preventing scarring, and senescence, and promoting wound healing. Moreover, research on the biology of exosomes is growing, which has enabled the creation of specific guidelines and quality control methodologies to support their potential implementation in the future. In this review, we have mainly focused on the role of exosomes in various dermatological diseases, their clinical applications, and the potential for further research pertaining to this.
The Role of Malassezia in Nonscarring Scalp Folliculitis, The Disease Course, and the Treatment Responses: A Retrospective Case Series
Authors: Altunel Cemile T. , Öztürk Meryem Ö. 
Published: March 2024

Abstract
Nonscarring scalp folliculitis (NSSF) has been poorly addressed in the literature. Previous studies have focused more on bacterial aetiology. Recent evidence has suggested an inflammatory hypothesis. Data on the role of Malassezia in NSSF are scarce. We retrospectively reviewed the hospital records of 26 NSSF patients diagnosed between September 2021 and October 2022. Malassezia spores were detected cytologically (May-Grünwald-Giemsa stain) in 96% of the patients. Fourteen patients underwent bacterial culture (no growth (4), coagulase-negative staphylococcus (9), and Staphylococcus aureus (1)). In total, 35% of patients had immunosuppression. Antifungal treatment reduced symptoms in 79% of the patients. Four patients received systemic isotretinoin. Recurrence was observed in 35% of patients. This case series suggests Malassezia should be recognized in the pathogenesis of NSSF, which should be confirmed by large-scale studies. Immunosuppression may serve as a predisposing factor in a subset of patients. Although antifungal treatment is efficient in most patients, frequent recurrences necessitate maintenance therapy.
Comparison of body image and peer relations among girls with normal, early, and late menarche
Authors: Irannezhad Elham , Fooladvand Maryam , Soltanizadeh Mohammad 
Published: March 2024

BACKGROUND:
The onset of menstruation is a turning point in women’s sexual maturity that, unlike other stages of growth, occurs abruptly and is a critical stage in girls’ lives. The present study investigated body image and peer relations among girls with early, late, and normal menarche.

MATERIALS AND METHODS:
This casual-comparative descriptive study included female students aged 9–17 in Isfahan. The participants were selected using multistage cluster random sampling. Out of 5,984 students, 56, 37, and 43 were selected for the normal, early, and late menarche groups. The Body Image Concern Inventory and Index of Peer Relations were the two tools used in this study. Moreover, the data were analyzed using a covariance statistical test.

RESULTS:
Girls with early menarche had better peer relations than those with late menarche (P = 0.01). In addition, there was a significant difference between adolescents with normal and late menarche in terms of body image (P = 0.01). Girls who experienced late menarche were more concerned about their body image and appearance; however, girls with early menarche experienced more impaired performance (P = 0.05).

CONCLUSION:
The first menstrual cycle, or menarche, affects psychological variables such as body image and peer relations. The later the menarche, the fewer problems in regard to body image and peer relations.
Iranian medical students’ E-learning continuance intention after end of COVID-19 pandemic
Authors: Ghalavand Hossein , Momtazan Mahboobeh , Jelvay Saeed , Khatamifar Seyed Hojjat , Heydarvand Zahra 
Published: March 2024

BACKGROUND:
Coronavirus disease (COVID-19) pandemic caused the closure of many face-to-face classes in Iran’s universities of medical sciences, so e-learning was adopted as the alternative method. This study aims to examine the medical students’ perspectives on e-learning continuance intention.

MATERIALS AND METHODS:
In this quantitative study, the population included 1,453 students and the statistical sample size was determined to be 305 students using the Cochran formula. The participants were selected using stratified sampling method based on the field of study and the data were collected by e-learning evaluation questionnaire. The data were analyzed using SPSS 26.0 in addition to descriptive statistics.

RESULTS:
The results showed the mean perceived autonomy, perceived competence, and communication in e-learning, intrinsic motivation, information quality, e-learning applicability and students’ satisfaction with e-learning courses were 2.61, 2.81, 2.91, 3.03, 2.98, 2.92, and 3.31, respectively. There was no significant correlation between the competence and applicability, user satisfaction and e-learning continuance intention. Moreover, e-learning continuance intention had the highest correlation with students’ satisfaction (0.787) and information applicability (0.784), respectively.

CONCLUSION:
Medical students had a tendency to continue e-learning, even after controlling the COVID-19 outbreak, and health education policymakers can be of use in this opportunity to developing educational services.
Joint modeling of longitudinal and competing risks for assessing blood oxygen saturation and its association with survival outcomes in COVID-19 patients
Authors: Geraili Zahra , HajianTilaki Karimollah , Bayani Masomeh , Hosseini Seyed R. , Khafri Soraya , Ebrahimpour Soheil , Javanian Mostafa , Babazadeh Arefeh , Shokri Mehran 
Published: March 2024

BACKGROUND:
The objective of the present study is to evaluate the association between longitudinal and survival outcomes in the presence of competing risk events. To illustrate the application of joint modeling in clinical research, we assessed the blood oxygen saturation (SPO2) and its association with survival outcomes in coronavirus disease (COVID-19).

MATERIALS AND METHODS:
In this prospective cohort study, we followed 300 COVID-19 patients, who were diagnosed with severe COVID-19 in the Rohani Hospital in Babol, the north of Iran from October 22, 2020 to March 5, 2021, where death was the event of interest, surviving was the competing risk event and SPO2 was the longitudinal outcome. Joint modeling analyses were compared to separate analyses for these data.

RESULT:
The estimation of the association parameter in the joint modeling verified the association between longitudinal outcome SPO2 with survival outcome of death (Hazard Ratio (HR) = 0.33, P = 0.001) and the competing risk outcome of surviving (HR = 4.18, P < 0.001). Based on the joint modeling, longitudinal outcome (SPO2) decreased in hypertension patients (β = -0.28, P = 0.581) and increased in those with a high level of SPO2 on admission (β = 0.75, P = 0.03). Also, in the survival submodel in the joint model, the risk of death survival outcome increased in patients with diabetes comorbidity (HR = 4.38, P = 0.026).

CONCLUSION:
The association between longitudinal measurements of SPO2 and survival outcomes of COVID-19 confirms that SPO2 is an important indicator in this disease. Thus, the application of this joint model can provide useful clinical evidence in the different areas of medical sciences.
Nursing institutions’ professors’ perception and distant education experience during COVID-19 pandemic lockdown
Authors: Sfendla Anis , Merabti Abdelilah , Lahjou Salwa , El Mlili Nisrin , Bahri Hind , Himmi Banacer , Lalami Abdelhakim El Ouali 
Published: March 2024

Background:
The nursing profession represents a demanding and challenging profession with a purpose to keep up with the evolving health-care demands of the population.

Aims:
The purpose of this study is to assess nursing institutions’ professors’ previous experience about information and communication technologies (ICTs) and their perception of distant education during the pandemic lockdown.

Materials and Methods:
This present is a cross-sectional study among participants n = 249 recruited from all academic staff (N = 694) of 23 higher institutes of nursing professions and health techniques in Morocco. The Chi-square test for independence (χ
2) and adjusted Z scores were used as a data analysis method to assess the association between the professors’ education levels and ICT experience.

Results:
A significant association [χ
2 (1, n = 249) = 19.510, P < 0.001] was revealed between professors’ education level and taken training related to ICT in education; significant few professors (16; 9.3%) reported that taken training session [χ
2 (1, n = 249) = 8.940, P = 0.003] belonged to the bachelor degree group. In matters of perception, a few proportion (10%) reported that using technology effectively belonged to the bachelor and low education background group.

Conclusions:
The findings showed that having previous experience in teaching remotely and training related to the ICT was significantly associated with a higher education background. Moreover, professors with higher degrees agreed that distant education could be an alternative to face-to-face course during quarantine.
Hand Injuries Onboard an Aircraft Carrier – A Case Series
Authors: Kalathil Akil Anand , Surse Yogeshwar Balasaheb 
Published: March 2024

Abstract
Hand injuries comprise a large part of all the injuries coming to the emergency department of the hospitals. Being the most important asset to man after the brain, any injury to the hands can cause lasting consequences. The importance of gross and fine motor skills of hands can hardly be stressed upon. The cases although common in a general scenario are not easily managed onboard a mobile platform with limited resources in terms of expertise, equipment, and manpower. In this case series, we describe the management of five injuries which took place onboard an aircraft carrier during sailing over a period of 9 months.
Artificial Intelligence in Health Care – A Study on Perceptions of and Readiness for Artificial Intelligence in Health-care Professionals
Authors: Tezpal Manvinder , Ghosh Subhodeep , Lalwani Radhika , Yadav Jyoti , Yadav Arun Kumar 
Published: March 2024

Abstract

Background:
With a call to action from the health-care industry and the Indian government, there are significant gaps in health-care professionals’ uptake and utilization of artificial intelligence (AI)-based tools. This study attempts to explore the current perceptions and readiness for AI among health-care workers.

Methods:
A web-based questionnaire comprising seven sections on descriptive educational and occupational data, AI familiarity level, role-specific training benefits, training advantages, implementation issues, driving factors, and perceived risks was designed from a literature search. Two additional domains of perception on professional impact and preparedness for AI in health care were estimated using a prevalidated Shinners AI Perception tool.

Results:
Of the 402 study participants, 192 (47.9%) were doctors from diverse specializations, and the remaining 209 (52.1%) were undergraduate medical and nursing students and affiliated health professionals. Although 79.8% of participants had never attended a course on AI, 82% agreed on the need for training in AI to explore new opportunities in their respective fields. 72.1% of participants agreed that data privacy and confidentiality posed the most significant challenge to AI implementation among the studied factors.

Conclusion:
This survey reveals awareness regarding AI, which is attributable to a lack of formal training received by health-care professionals. Most participants believed that AI could improve population health outcomes, and collective efforts are needed to make this belief a reality.