bluuebunny/crossref_metadata_2025_split huggingface dataset:
4‐Hydroxy‐2‐quinolones. Part 95. Synthesis, Structure, and Antitubercular Properties of Hetarylamides of 4‐Hydroxy‐2‐oxo‐1,2,5,6,7,8‐hexahydroquinoline‐3‐carboxylic Acid.
Authors: Ukrainets I. V. , Kolesnik E. V. , Sidorenko L. V. , Gorokhova O. V. , Turov A. V. 
Published: February 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
4‐Hydroxy‐2‐quinolones. Part 96. Synthesis and Properties of 4‐Methyl‐2‐oxo‐1,2‐dihydroquinoline‐3‐carboxylic Acid.
Authors: Ukrainets I. V. , Sidorenko L. V. , Gorokhova O. V. , Shishkina S. V. 
Published: February 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Enantioselective Synthesis of the Farnesyltransferase Inhibitor, A‐345665.0.
Authors: Rozema Michael J. , Fickes Michael , McLaughlin Maureen , Rohde Bridget , McDermott Todd 
Published: February 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Novel Hydrophobic Broensted Acidic Ionic Liquids as Efficient and Reusable Catalysts for Organic Reactions in Water.
Authors: Gu Yanlong , Ogawa Chikako , Kobayashi Shu 
Published: February 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Biocatalytic Synthesis of Highly Enantiopure 1,4‐Benzodioxane‐2‐carboxylic Acid and Amide.
Authors: Liu Jun , Wang De‐Xian , Zheng Qi‐Yu , Wang Mei‐Xiang 
Published: February 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Transformations of Methyl 6‐Methyl‐2‐methylsulfanyl‐4‐oxo‐3,4‐dihydro‐3‐pyrimidinylacetate under Oxidative Conditions.
Authors: Jakubkiene V. , Vainilavicius P. 
Published: February 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
The Development of 2‐Benzimidazole Substituted Pyrimidine Based Inhibitors of Lymphocyte Specific Kinase (Lck).
Authors: Sabat Mark , et al. et al. 
Published: February 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Synthesis and Antitumor Activities of Novel Pyrazolo[1,5‐a]pyrimidines.
Authors: Li Juan , Zhao Yan Fang , Zhao Xiang Lin , Yuan Xiao Ye , Gong Ping 
Published: February 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Synthesis, Insecticidal and Antimicrobial Activities of Some Heterocyclic Derivatives of Quinazolinone.
Authors: Singh Tripti , Sharma Shalabh , Srivastava Virendra Kishore , Kumar Ashok 
Published: February 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
New Approach Towards Cytotoxic Furyl Macrolactones by Ring Closing Metathesis.
Authors: Krauss J. , Bracher F. , Unterreitmeier D. 
Published: February 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Copper‐Catalyzed β‐Boration of α,β‐Unsaturated Carbonyl Compounds: Rate Acceleration by Alcohol Additives.
Authors: Mun Soungyun , Lee Ji‐Eon , Yun Jaesook 
Published: February 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Ligand‐Controlled, Complementary Stereoselectivity in the Platinum‐Catalyzed Intramolecular Silaboration of Alkenes.
Authors: Ohmura Toshimichi , Furukawa Hideki , Suginome Michinori 
Published: February 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
High Turnover Frequency Observed in Catalytic Enantioselective Additions of Enecarbamates and Enamides to Iminophosphonates.
Authors: Kiyohara Hiroshi , Matsubara Ryosuke , Kobayashi Shu 
Published: February 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
In vivo Antitumor, in vitro Antibacterial Activity and Alkylating Properties of Phosphorohydrazine Derivatives of Coumarin and Chromone.
Authors: Nawrot‐Modranka Jolanta , Nawrot Ewa , Graczyk Julita 
Published: February 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Xylogranatins A—D: Novel Tetranortriterpenoids with an Unusual 9,10‐seco Scaffold from Marine Mangrove Xylocarpus granatum
Authors: Yin Sheng , Fan Cheng‐Qi , Wang Xiao‐Ning , Lin Li‐Ping , Ding Jian , Yue Jian‐Min 
Published: February 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Convergent and Diastereoselective Synthesis of the Polycyclic Pyran Core (I) of Saudin (II).
Authors: Tambar Uttam K. , Kano Taichi , Zepernick John F. , Stoltz Brian M. 
Published: February 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
An Efficient Ring‐Closing Metathesis Reaction Based Approach to 1,2,2‐Trimethylcyclopentanemethanol. Formal Synthesis of (.+‐.)‐Herbertene and (.+‐.)‐Cuparenes.
Authors: Srikrishna A. , Satyanarayana G. 
Published: February 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Total Synthesis of Tubulysin U (Ia) and V (Ib).
Authors: Doemling Alexander , Beck Barbara , Eichelberger Uwe , Sakamuri Sukumar , Menon Sanjay , Chen Quin‐Zene , Lu Yingchun , Wessjohann Ludger A. 
Published: February 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Total Synthesis of Azumamides A and E.
Authors: Izzo Irene , Maulucci Nakia , Bifulco Giuseppe , De Riccardis Francesco 
Published: February 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Alternative Synthetic Routes to 2′,3′‐Didehydro‐2′,3′‐dideoxy‐5‐hydroxymethyluridine.
Authors: Chung Raymond , Anderson Karen S. 
Published: February 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
A Concise Total Synthesis of the Lichen Macrolide (+)‐Aspicilin.
Authors: Dubost Christophe , Marko Istvan E. , Ryckmans Thomas 
Published: February 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
The Changing Faces of Halogenated Marine Natural Products: Total Synthesis of the Reported Structures (I) and (II) of Elatenyne and an Enyne from Laurencia majuscula.
Authors: Sheldrake Helen M. , Jamieson Craig , Burton Jonathan W. 
Published: February 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
anti‐AIDS Agents 68. The First Total Synthesis of a Unique Potent anti‐HIV Chalcone (I) from Genus Desmos.
Authors: Nakagawa‐Goto Kyoko , Lee Kuo‐Hsiung 
Published: February 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Hyosmin, a New Lignan from Hyoscyamus niger L.
Authors: Begum Ahil Sajeli , Verma Shweta , Sahai Mahendra , Asai Teigo , Hara Noriyuki , Fujimoto Yoshinori 
Published: February 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Synthesis of the Entire Framework (IV) of Tartrolon B Utilizing a Silicon‐Tethered Ring‐Closing Metathesis Strategy.
Authors: Kim Yi Jin , Lee Daesung 
Published: February 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
A Simple Procedure for the Synthesis of 4‐Aza‐podophyllotoxin Derivatives in Water under Microwave Irradiation Conditions.
Authors: Tu Shujiang , Zhang Yan , Zhang Junyong , Jiang Bo , Jia Runhong , Zhang Jinpeng , Ji Shunjun 
Published: February 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Asymmetric Synthesis of (‐)‐Mitorubrin and Related Azaphilone Natural Products
Authors: Zhu Jianglong , Porco John A. Jr. 
Published: February 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
A Fast Assembly of (‐)‐Epigallocatechin‐3‐gallate [(‐)‐EGCG] (VII) via Intra‐ and Inter‐Molecular Mitsunobu Reaction.
Authors: Ding Tong‐Jian , Wang Xiao‐Long , Cao Xiao‐Ping 
Published: February 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Hydrogen‐Bonded Oligo(p‐phenylenevinylene) Functionalized with Perylene Bisimide: Self‐Assembly and Energy Transfer.
Authors: Zhang Jian , Hoeben Freek J. M. , Pouderoijen Maarten J. , Schenning Albertus P. H. J. , Meijer E. W. , De Schryver Frans C. , De Feyter Steven 
Published: February 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Materials Chemistry under High Pressures — Some Recent Aspects
Authors: Demazeau Gerard , Huppertz Hubert , Alonso Jose A. , Poettgen Rainer , Moran Emilio , Attfield J. Paul 
Published: February 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Synthesis of Fine Chemicals by the Conjugate Addition of Nitroalkanes to Electrophilic Alkenes
Authors: Ballini R. , Barboni L. , Bosica G. , Fiorini D. , Palmieri A. 
Published: February 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Physiological reactions of preschoolers to fear‐inducing film clips: Effects of temperamental fearfulness and quality of the parent–child relationship
Authors: Gilissen Renske , Koolstra Cees M. , van IJzendoorn Marinus H. , Bakermans‐Kranenburg Marian J. , van der Veer René 
Published: February 2007

AbstractThis study investigates young children's fright reactions induced by television. The central question concerns the degree to which the impact can be predicted by temperamental fearfulness and the quality of the parent–child relationship. Using a procedure for recording simultaneously skin conductance (SCL) and heart rate variability (RMSSD), 78 3‐ and 4‐year‐olds were shown two brief TV film episodes (one fear‐inducing and one emotionally neutral). The children responded to fear‐inducing film stimuli with an increase in SCL‐reactivity and a decrease in RMSSD‐reactivity. Furthermore, temperamentally more fearful children showed most electrodermal reactivity when their relationship with the parent was less harmonious. More fearful children were more susceptible to the quality of the relationship with their parent, which provides support for the differential susceptibility hypothesis. © 2007 Wiley Periodicals, Inc. Dev Psychobiol 49: 187–195, 2007.
Brain plasticity and recovery from early cortical injury
Authors: Kolb Bryan , Gibb Robbin 
Published: February 2007

AbstractThere is a general view that early brain damage leads to a far better outcome than damage later in life. Although there is a grain of truth to this idea, the reality is far more complex. We have identified a set of nine principles that underlie behavioral and anatomical changes after neonatal cortical injury as well as describing a variety of pre‐ and postnatal factors that modulate brain and behavioral plasticity after neonatal cortical lesions. © 2007 Wiley Periodicals, Inc. Dev Psychobiol 49: 107–118, 2007.
Maternal stress and behavior modulate relationships between neonatal stress, attention, and basal cortisol at 8 months in preterm infants
Authors: Tu Mai Thanh , Grunau Ruth E. , Petrie‐Thomas Julie , Haley David W. , Weinberg Joanne , Whitfield Michael F. 
Published: February 2007

AbstractThere is evidence that the developmental trajectory of cortisol secretion in preterm infants is altered, with elevated basal cortisol levels observed postnatally through at least 18 months corrected age (CA). This alteration is possibly due to neonatal pain‐related stress. High cortisol levels might contribute to greater risk of impaired neurodevelopment. Since maternal factors are important for the regulation of infant stress responses, we investigated relationships between infant (neonatal pain‐related stress, attention, cortisol) and maternal (stress, interactive behaviors) factors at age 8 months CA. We found that interactive maternal behaviors buffered the relationship between high neonatal pain‐related stress exposure and poorer focused attention in mothers who self‐reported low concurrent stress. Furthermore, in preterm infants exposed to high concurrent maternal stress and overwhelming interactive maternal behaviors, higher basal cortisol levels were associated with poor focused attention. Overall, these findings suggest that maternal factors can influence the cognitive resilience at 8 months of preterm infants exposed to early life stress. © 2007 Wiley Periodicals, Inc. Dev Psychobiol 49: 150–164, 2007.
New (1‐Phosphanylferrocen‐1′‐ and ‐2‐yl)methyl‐Linked Diaminocarbene Ligands: Synthesis and Rhodium(I) Complexes
Authors: Labande Agnès , Daran Jean‐Claude , Manoury Eric , Poli Rinaldo 
Published: February 2007

AbstractTwo ferrocenylmethanols, [1′‐(diphenylthiophosphanyl)ferrocen‐1‐yl]methanol (3) and [2‐(diphenylthiophosphanyl)ferrocen‐1‐yl]methanol (6), have been converted in one step into the 1,1′‐ and 1,2‐ferrocenediyl‐linked thiophosphane/N‐R‐imidazolium salts 4a,b and 7a,b (a: R = Me; b: R = 2,4,6‐Me3C6H2 or Mes). This straightforward method allows the linkage of an imidazolium group to a ferrocene unit with a nonsubstituted methylene bridge. After desulfurisation of the phosphane group, the ligands reacted with an RhI precursor, in the presence of tBuOK, to give cationic complexes 9a,b and 10a,b. All compounds were characterised by elemental analysis, NMR spectroscopy and mass spectrometry. The molecular structures of compounds 4a, 7a and 9a were determined by X‐ray crystallography. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2007)
Major depressive disorder is accompanied with oxidative stress: short‐term antidepressant treatment does not alter oxidative–antioxidative systems
Authors: Sarandol Asli , Sarandol Emre , Eker Salih Saygin , Erdinc Selda , Vatansever Ebru , Kirli Selcuk 
Published: February 2007

AbstractObjectiveThe aim of the present study was to investigate the oxidative–antioxidative systems and effects of different antidepressants on these systems in patients with major depressive disorder (MDD).MethodNinety‐six patients with a Diagnostic and Statistical Manual of Mental Disorders Fourth Edition (DSM‐IV) diagnosis of MDD and 54 healthy controls were included in the study. Plasma malondialdehyde (MDA) levels and susceptibility of red blood cells (RBCs) to oxidation were determined to investigate the oxidative status, plasma vitamin E, vitamin C, serum total carotenoid levels, total antioxidant capacity (TAOC), RBC superoxide dismutase (SOD) and whole blood glutathione peroxidase (GPx) activities were measured to investigate the antioxidative defence before and after 6 weeks of antidepressant treatment.ResultsPlasma MDA levels and susceptibility of RBCs to oxidation were significantly higher in the MDD group compared with the control group. RBC SOD activity was significantly increased in patients with MDD, and furthermore there was a significant positive correlation between the severity of the disease and SOD activity.ConclusionMDD is accompanied with oxidative stress; however, oxidative–antioxidative systems do not seem to be affected by 6 weeks of antidepressant treatment. Copyright © 2007 John Wiley & Sons, Ltd.
Evaluation of physiologically based pharmacokinetic models for use in risk assessment
Authors: Chiu Weihsueh A. , Barton Hugh A. , DeWoskin Robert S. , Schlosser Paul , Thompson Chad M. , Sonawane Babasaheb , Lipscomb John C. , Krishnan Kannan 
Published: February 2007

AbstractPhysiologically based pharmacokinetic (PBPK) models are sophisticated dosimetry models that offer great flexibility in modeling exposure scenarios for which there are limited data. This is particularly of relevance to assessing human exposure to environmental toxicants, which often requires a number of extrapolations across species, route, or dose levels. The continued development of PBPK models ensures that regulatory agencies will increasingly experience the need to evaluate available models for their application in risk assessment. To date, there are few published criteria or well‐defined standards for evaluating these models. Herein, important considerations for evaluating such models are described. The evaluation of PBPK models intended for risk assessment applications should include a consideration of: model purpose, model structure, mathematical representation, parameter estimation, computer implementation, predictive capacity and statistical analyses. Model purpose and structure require qualitative checks on the biological plausibility of a model. Mathematical representation, parameter estimation, computer implementation involve an assessment of the coding of the model, as well as the selection and justification of the physical, physicochemical and biochemical parameters chosen to represent a biological organism. Finally, the predictive capacity and sensitivity, variability and uncertainty of the model are analysed so that the applicability of a model for risk assessment can be determined. Published in 2007 by John Wiley & Sons, Ltd.
Transactivation of Src, PDGF receptor, and Akt is involved in IL‐1β‐induced ICAM‐1 expression in A549 cells
Authors: Lin Chih‐Chung , Lee Chiang‐Wen , Chu Tzu‐Hua , Cheng Ching‐Yi , Luo Shue‐Fen , Hsiao Li‐Der , Yang Chuen‐Mao 
Published: February 2007

AbstractIn previous study, interleukin‐1β (IL‐1β) has been shown to induce ICAM‐1 expression through MAPKs and NF‐κB in A549 cells. In addition to these pathways, transactivation of non‐receptor tyrosine kinase (Src), PDGF receptors (PDGFRs), and phosphatidylinositol 3‐kinase (PI3K)/Akt has been implicated in the expression of inflammatory genes. Here, we further investigated whether these different mechanisms participating in IL‐1β‐induced ICAM‐1 expression in A549 cells. We initially observed that IL‐1β‐induced ICAM‐1 promoter activity was attenuated by the inhibitors of Src (PP1), PDGFR (AG1296), PI3‐K (LY294002 and wortmannin), and Akt (SH‐5), revealed by reporter gene assay, Western blotting, and RT‐PCR analyses. The involvement of Src and PI3‐K/Akt in IL‐1β‐induced ICAM‐1 expression was significantly attenuated by transfection of A549 cells with dominant negative plasmids of Src, p85 and Akt, respectively. Src, PDGFR, and PI3K/Akt mediated the effects of IL‐1β because pretreatment with PP1, AG1296, and wortmannin also abrogated IL‐1β‐stimulated Src, PDGFR, and Akt phosphorylation, respectively. Moreover, pretreatment with p300 inhibitor (curcumin) also blocked ICAM‐1 expression. We further confirmed that p300 was associated with ICAM‐1 promoter which was dynamically linked to histone H4 acetylation stimulated by IL‐1β, determined by chromatin immunoprecipitation assay. Association of p300 and histone‐H4 to ICAM‐1 promoter was inhibited by LY294002. Up‐regulation of ICAM‐1 enhanced the adhesion of neutrophils onto A549 cell monolayer exposed to IL‐1β, which was inhibited by PP1, AG1296, LY294002, wortmannin, and helenalin. These results suggested that Akt phosphorylation mediated through transactivation of Src/PDGFR promotes the transcriptional p300 activity and eventually leads to ICAM‐1 expression induced by IL‐1β. J. Cell. Physiol. 211: 771–780, 2007. © 2007 Wiley‐Liss, Inc.