bluuebunny/crossref_metadata_2025_split huggingface dataset:
Investigating the efficacy of an exopolysaccharide (EPS)‐producing strain Lactiplantibacillus plantarum L75 on oat silage fermentation at different temperatures
Authors: Su Rina , Liang Ying , Chen Hu , Sheoran Neha , Ke Wencan , Bai Jie , Jia Mengya , Zhu Jie , Li Qiang , Liu Qi , Chen Xiaojun , Guo Xusheng 
Published: April 2024

AbstractThis study investigates the effectiveness of an exopolysaccharide (EPS)‐producing strain (Lactiplantibacillus plantarum L75) alone or in combination with Saccharomyces cerevisiae on the fermentation characteristics, antioxidant capacities and microbial community successions of oat silage stored at various temperatures. A rapid decrease in pH and lactic acid accumulation was observed in silages treated with L. plantarum and S. cerevisiae (LS) as early as 3 days of ensiling (p < 0.05). Over the ensiling period of 7–60 days, L. plantarum (L)‐inoculated groups showed the lowest pH, lowest ammonia nitrogen and the highest amount of lactic acid regardless of the storage temperatures. When the oat silage was stored at 15°C, LS‐inoculated group exhibited a higher superoxide dismutase (SOD) activity than control and L‐inoculated group. Furthermore, the proportion of Lactiplantibacillus in the combined inoculation group increased by 65.42% compared to the L‐inoculated group (33.26%). Fungal community data revealed abundant Penicillium carneum in the control and L‐inoculated groups stored at 15°C. Conclusively, these results showed that combined inoculation of L. plantarum L75 and S. cerevisiae improved the fermentation quality of oat silage at 15°C, thus proposing a technique for enhancing the fermentation quality of silage in regions with low temperatures during harvest season.
Assessing microbial plastic degradation requires robust methods
Authors: Obrador‐Viel Theo , Zadjelovic Vinko , Nogales Balbina , Bosch Rafael , Christie‐Oleza Joseph A. 
Published: April 2024

AbstractPlastics are versatile materials that have the potential to propel humanity towards circularity and ultimate societal sustainability. However, the escalating concern surrounding plastic pollution has garnered significant attention, leading to widespread negative perceptions of these materials. Here, we question the role microbes may play in plastic pollution bioremediation by (i) defining polymer biodegradability (i.e., recalcitrant, hydrolysable and biodegradable polymers) and (ii) reviewing best practices for evaluating microbial biodegradation of plastics. We establish recommendations to facilitate the implementation of rigorous methodologies in future studies on plastic biodegradation, aiming to push this field towards the use of isotopic labelling to confirm plastic biodegradation and further determine the molecular mechanisms involved.
Problem gambling in psychotic disorders: A systematic review and meta‐analysis of prevalence
Authors: Corbeil Olivier , Anderson Élizabeth , Béchard Laurent , Desmeules Charles , Huot‐Lavoie Maxime , Bachand Lauryann , Brodeur Sébastien , Carmichael Pierre‐Hugues , Jacques Christian , Solmi Marco , Giroux Isabelle , Dorval Michel , Demers Marie‐France , Roy Marc‐André 
Published: April 2024

AbstractIntroductionProblem gambling (PBG) is more common in people with mental health disorders, including substance use, bipolar, and personality disorders, than in the general population. Although individuals with psychotic disorders might be expected to be more vulnerable to PBG, fewer studies have focused on this comorbidity. The aim of this review was to estimate the prevalence of PBG in people with psychotic disorders.MethodsMedline (Ovid), EMBASE, PsycINFO (Ovid), CINAHL, CENTRAL, Web of science, and ProQuest were searched on November 1, 2023, without language restrictions. Observational and experimental studies including individuals with psychotic disorders and reporting the prevalence of PBG were included. Risk of bias was assessed using the Joanna Briggs Institute critical appraisal for systematic reviews of prevalence data. The pooled prevalence of PBG was calculated using a fixed effects generalized linear mixed model and presented through forest plots.ResultsOf 1271 records screened, 12 studies (n = 3443) were included. The overall prevalence of PBG was 8.7% (95% CI = 7.8%–9.7%, I2 = 69%). A lower prevalence was found in studies with a low risk of bias (5.6%; 95% CI = 4.4%–7.0%) compared with studies with a moderate risk of bias (10.4%; 95% CI = 9.2%–11.7%). Different methods used to assess PBG also contributed to the heterogeneity found.ConclusionThis meta‐analysis found substantial heterogeneity, partly due to the risk of bias of the included studies and a lack of uniformity in PBG assessment. Although more research is needed to identify those at increased risk for PBG, its relatively high prevalence warrants routine screening for gambling in clinical practice.
Comparative evaluation of full and partial pulpotomy in permanent teeth with irreversible pulpitis: A systematic review and meta‐analysis
Authors: Kumar Vishal , Chawla Amrita , Priya Harsh , Sachdeva Akshat , Sharma Sidhartha , Kumar Vijay , Logani Ajay 
Published: April 2024

AbstractThe purpose of this systematic review and meta‐analysis is to conduct a comparative evaluation of partial and full pulpotomy techniques in cariously exposed teeth with symptoms indicative of symptomatic irreversible pulpitis. Databases such as PubMed, EMBASE, Cochrane, and Web of Science were searched. Studies evaluating and/or comparing clinical and/or radiographic success of partial and full pulpotomy in teeth diagnosed with irreversible pulpitis with a minimum of 12 months follow‐up were included. The risk of bias (ROB) tool was used for the assessment of ROB. A meta‐analysis was conducted to compare the healing outcome of partial and full pulpotomy. Three studies fulfilled the inclusion criteria, there was a low risk of bias in each of the five domains. Full pulpotomy had a higher success rate than partial pulpotomy, according to meta‐analysis, but the difference was not statistically significant.
Young adults' perception of transition from paediatric to adult care
Authors: Forsberg Johanna , Lööf Gunilla , Burström Åsa 
Published: April 2024

AbstractAimMedical advancements will lead to more children with long‐term illnesses and/or disabilities undergoing the transition to adult care. Previous studies show that many young adults are unprepared for this transition, and might suffer from loss of follow‐up. This study aimed to investigate the post‐transfer experiences of the transition among young adults with long‐term illnesses and/or disabilities.MethodsA qualitative descriptive design was used. Three semi‐structured focus group interviews were conducted with 15 participants (18–25 years of age) recruited via patient organisations focusing on children and young adults with disabilities and/or long‐term illnesses. The interviews were analysed with conventional content analysis.ResultsOne theme emerged: limbo, defined as an indefinite experience without knowing when or even if something would happen, or whether they would be overlooked. The theme rested on four categories: transition experiences, organisational aspects, influence on daily life, and self‐management.ConclusionAreas for improvement were identified across the entire transition that is, in the preparation, transfer, and post‐transfer stages. Our findings indicate a limited understanding among healthcare providers (HCPs) that the transition continues until the young adult has been fully integrated into adult care.
Feed characteristics of dried corn grain and corn grain silage produced in Japan compared with imported corn grain
Authors: Touno Eiko , Tagawa Shin‐ichi , Kamizono Tomomi , Kunizane Hisanori , Uchino Hiroshi , Kawamoto Hidenori , Uozumi Sunao , Deguchi Shin 
Published: April 2024

AbstractWe compared the in situ dry matter degradability (ISDMD) and crude protein degradability (ISCPD) of high‐moisture corn grain silage and dried corn grains produced in Japan (JHC and JDC, respectively) with corn grains imported from the United States (USC), Brazil (BRC), and South Africa (SAC). The ISDMD values of USC, BAC, and SAC were between those of JHC and JDC, but ISDMD did not differ significantly between USC and SAC. In contrast, ISDMD was lower for BAC than USC and SAC. Overall, our results indicate that ISDMD and ISCPD in the rumen differ between corn grains sources (domestic compared with imported and between production locations), primarily due to differences between the corn varieties represented. In particular, the ISDMD and ISCPD of JHC were greater than those of JDC, and this difference in degradability needs to be considered when using high‐moisture corn grain silage as a substitute for dried corn grain as a feed for dairy cattle.
Exploring promising minor natural phenolic compounds in neuroprotection‐related preclinical models
Authors: Moreira Vasconcelos Carlos Franciney , Neugebauer Agnieszka Zofia , Basto Souza Ricardo 
Published: April 2024

AbstractNeurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease, are characterised by the progressive loss of specific neuronal cell populations due to multifactorial factors, including neurochemical and immunological disturbances. Consequently, patients can develop cognitive, motor and behavioural dysfunctions, which lead to impairments in their quality of life. Over the years, studies have reported on the neuroprotective properties inherent in phenolic compounds. Therefore, this review highlights the most recent scientific findings regarding phenolic compounds as promising neuroprotective molecules against neurodegenerative diseases.
A comprehensive histomolecular characterization of meningioangiomatosis: Further evidence for a precursor neoplastic lesion
Authors: Tauziède‐Espariat Arnault , Masliah‐Planchon Julien , Sievers Philipp , Sahm Felix , Dangouloff‐Ros Volodia , Boddaert Nathalie , Hasty Lauren , Aboubakr Oumaima , Métais Alice , Chrétien Fabrice , Roux Alexandre , Pallud Johan , Blauwblomme Thomas , Beccaria Kévin , Bourdeaut Franck , Puget Stéphanie , Varlet Pascale 
Published: April 2024

AbstractMeningioangiomatosis (MAM) remains a poorly understood lesion responsible for epileptic disease. In the past, MAM was primarily described in the context of neurofibromatosis type 2 before being mainly reported sporadically. Moreover, the malformative or tumoral nature is still debated. Because a subset of MAM are associated with meningiomas, some authors argue that MAM corresponds to an infiltration pattern of these tumors. For these reasons, MAM has not been added to the World Health Organization (WHO) Classification of Central Nervous System Tumors as a specific entity. In the present study, we characterized a series of pure MAM (n = 7) and MAM associated with meningiomas (n = 4) using histopathology, immunohistochemistry, genetic (fluorescent in situ and DNA sequencing analyses), and epigenetic (DNA‐methylation profiling) data. We evidenced two distinct morphological patterns: MAM with a fibroblastic‐like pattern having few lesional cells, and MAM with a more cellular pattern. A subset was associated with the genetic alterations previously reported in meningiomas (such as a KMT2C mutation and a hemizygous deletion of chromosome 22q including the NF2 gene). The DNA‐methylation profile, using a t‐distributed stochastic neighbor embedding analysis, evidenced that MAM (pure or associated with meningiomas) clustered in a separate group from pediatric meningiomas. The present results seem to suggest that MAM represents a neoplastic lesion and encourage the further study of similar additional series so that it may be included in a future WHO classification.
English tweets on allergy: Content analysis and association with surveillance data
Authors: Sousa‐Pinto Bernardo , Jankin Slava , Vieira Rafael José , Marques‐Cruz Manuel , Fonseca João Almeida , Bousquet Jean 
Published: April 2024

AbstractBackgroundAnalysis of X (formerly Twitter) posts can inform on the interest/perceptions that social media users have on health subjects. In this study, we aimed to analyse tweets on allergic conditions, comparing them with surveillance data.MethodsWe retrieved tweets from England on “allergy,” “asthma,” and “allergic rhinitis,” published between 2016 and 2021. We estimated the correlation between the frequency of tweets on “asthma” and “allergic rhinitis” and English surveillance data on the incidence of asthma and allergic rhinitis medical visits. We performed sentiment analysis, computing a score informing on the emotional tone of assessed tweets. We applied a topic modelling approach to identify topics (clusters of words frequently occurring together) for tweets on each assessed condition.ResultsWe analysed a total of 13,605 tweets on “allergy,” 7767 tweets on “asthma,” and 11,974 tweets on “allergic rhinitis.” Food‐related words were preponderant on tweets on “allergy,” while “eyes” was the most frequent meaningful word on “allergy rhinitis” tweets. We observed seasonal patterns for tweets on “allergic rhinitis,” both in their frequency and sentiment – the incidence of allergic rhinitis medical visits was moderately to strongly correlated with the frequency (ρ = 0.866) and sentiment (ρ = −0.474) of tweets on “allergic rhinitis.” For tweets on “asthma,” no such patterns/correlations were observed. The average sentiment score was negative for all assessed conditions, ranging from −0.004 (“asthma”) to −0.083 (“allergic rhinitis”).ConclusionsTweets on “allergic rhinitis” displayed a seasonal pattern regarding their frequency and sentiment, which correlated with surveillance data. No such patterns were observed for “asthma.”
A randomized clinical trial on zirconia versus titanium implants in maxillary single tooth replacement
Authors: de Beus J. H. W. , Cune M. S. , Slot J. W. A. , Jensen‐Louwerse C. , la Bastide‐van Gemert S. , Meijer H. J. A. , Raghoebar G. M. , Schepke U. 
Published: April 2024

AbstractObjectivesThis RCT aimed to compare zirconia and titanium dental implants in the maxillary premolar region. The comparison was based on marginal bone level (MBL) changes, clinical parameters, aesthetic outcomes, and patient related outcome measures (PROMs) 1 year after prosthetic loading.Materials and MethodsFifty patients were randomly assigned to receive either a zirconia (ZrO2, n = 25) implant or a titanium (Ti, n = 25) bone‐level implant. Implants were provided with a lithium disilicate crown 3 months after placement. Follow‐up was at 1 month and after 1 year. The primary outcome pertained to changes in MBL. Reported secondary outcomes consisted of implant survival, peri‐implant tissue health, aesthetics, and PROMs.ResultsMean MBL change after 1 year was 0.01 mm (SD = 0.45; min = 0.72, max = 0.86) for ZrO2 and −0.09 mm (SD = 0.34; min = 0.53, max = −1.06) for Ti (p = .439). Scores for the other clinical outcome parameters and PROMs were generally favorable, with no significant differences. However, significant differences were found for the aesthetic outcomes regarding two criteria: (a) level of facial mucosa (p = .022), in favor of Ti, and (b) root convexity/soft tissue color and texture (p = .005) in favor of ZrO2.Conclusion and clinical implicationsThe ZrO2 and Ti implant types used in this study, replacing a single missing maxillary premolar, show a comparable outcome in terms of MBL change after 1 year. Clinical and aesthetic parameters, as well as PROMs, are favorable and similar between both implant types after 1 year of prosthetic loading. These short‐term study results suggest that both are suitable for clinical use.
Mortality and morbidity after combined heart and liver transplantation in the failing Fontan: An updated dual center retrospective study
Authors: Vaikunth Sumeet S. , Ortega‐Legaspi Juan M. , Conrad Desiree R. , Chen Sharon , Daugherty Tami , Haeffele Christiane L. , Teuteberg Jeffrey , Mclean Rhondalynn , MacArthur John W. , Woo Y. Joseph , Maeda Katsuhide , Ma Michael , Nasirov Teimour , Hoteit Marrouf , Hilscher Moira B. , Wald Joyce , Mandelbaum Tal , Olthoff Kim M. , Abt Peter L. , Atluri Pavan , Cevasco Marisa , Mavroudis Constantine D. , Fuller Stephanie , Lui George K. , Kim Yuli Y. 
Published: April 2024

AbstractIntroductionAs the adult Fontan population with Fontan associated liver disease continues to increase, more patients are being referred for transplantation, including combined heart and liver transplantation.MethodsWe report updated mortality and morbidity outcomes after combined heart and liver transplant in a retrospective cohort series of 40 patients (age 14 to 49 years) with Fontan circulation across two centers from 2006–2022.ResultsThe 30‐day, 1‐year, 5‐year and 10‐year survival rate was 90%, 80%, 73% and 73% respectively. Sixty percent of patients met a composite comorbidity of needing either post‐transplant mechanical circulatory support, renal replacement therapy or tracheostomy. Cardiopulmonary bypass time > 283 min (4.7 h) and meeting the composite comorbidity were associated with mortality by Kaplan Meier analysis.ConclusionFurther study to mitigate early mortality and the above comorbidities as well as the high risk of bleeding and vasoplegia in this patient population is warranted.
Reject or revise: Gender differences in persistence and publishing in economics
Authors: Shastry Gauri Kartini , Shurchkov Olga 
Published: April 2024

AbstractWe design an experiment to study gender differences in reactions to editorial decisions on submissions to top economics journals. Respondents read a hypothetical editor's letter where the decision (e.g., revise and resubmit) is randomized across participants. Relative to an R&R, female assistant professors who receive a rejection perceive a significantly lower likelihood of subsequently publishing the paper in any leading journal than comparable male assistant professors. We do not find this gender difference among tenured professors. We consider several mechanisms, pointing to gender differences in attribution of negative feedback to ability and confidence under time constraints as likely explanations.
Effects of sub‐nanogram doses of acetamiprid, dimethoate, flupyradifurone, and sulfoxaflor on courtship, mating, and olfactory host finding of the parasitic wasp Lariophagus distinguendus
Authors: Schöfer Nils , Ratschmann Gabriel , Ruther Joachim 
Published: April 2024

AbstractContinued use and development of new insecticides are seen as a necessary part of modern agriculture, but insecticides, even at sublethal levels, may also affect beneficial non‐target species, such as pollinators, predators, and parasitic wasps. Here, we studied sublethal effects of four insecticides – acetamiprid, dimethoate, flupyradifurone, and sulfoxaflor – all targeting cholinergic neurons in insects, on sexual communication and olfactory host finding in the parasitic wasp Lariophagus distinguendus (Förster) (Hymenoptera: Pteromalidae). We found that all four insecticides reduced, at least at one of the tested sublethal doses, pheromone‐mediated courtship behaviour (wing fanning) in males and the mating frequency of treated wasps. Treated females no longer preferred host‐associated kairomones. This suggests that the olfactory sense of the wasps is hampered by sublethal insecticide doses. The lowest bioactive doses tested in the bioassays were 0.021 ng for sulfoxaflor and 0.105 ng for acetamiprid, dimethoate, and flupyradifurone. These low amounts are field realistic and might be taken up by the wasps, e.g., by feeding contaminated plant nectar. Exposure to these compounds likely compromises the important ecosystem service provided by parasitic wasps as natural enemies in terrestrial ecosystems.
Pseudoplagiostoma eucalypti: An emerging pathogen of Eucalyptus in northern India
Authors: Negi Nitika , Ramkrishna  , Meena Rajendra K. , Pandey Amit , Bhandari Maneesh S. , Pandey Shailesh 
Published: April 2024

AbstractIn December 2022, a leaf spot and blight disease was observed in Eucalyptus plantations in northern India. Morphological features coupled with phylogenetic analysis of combined internal transcribed spacer (ITS), translation elongation factor 1‐alpha (tef1) and β‐tubulin (tub2) regions confirmed the association of Pseudoplagiostoma eucalypti with the disease symptoms. The pathogenicity of P. eucalypti was first proved on detached leaves of Eucalyptus camaldulensis and reconfirmed in glasshouse inoculation experiments. Finally, Koch's postulates were fulfilled by re‐isolating the pathogen from the inoculated leaves. This pathogen was first described in 1995 from the leaves of Eucalyptus spp. collected from southern India, and this study confirms its first serious occurrence after more than two decades in northern India. In addition, this is the first report on the polyphasic characterization of P. eucalypti from India.
Comparing brief video interventions to reduce public and self‐stigma: Randomized control trial
Authors: Amsalem Doron , Jankowski Samantha E. , Markowitz John C. , Stroup T. Scott , Dixon Lisa B. , Pope Leah G. 
Published: April 2024

AbstractAimStigma is a major mental healthcare barrier. This study compares the efficacy of two types of brief video interventions, targeting public and self‐stigma, in reducing public stigma towards people living with psychosis. We hypothesized both interventions would similarly reduce public stigma and outperform the control group. As a secondary analysis, we explored the effect of familiarity with a person living with serious mental illness (SMI).MethodsParticipants (N = 1215) aged 18–35 recruited through crowdsourcing were assessed pre‐ and post‐intervention and at 30‐day follow‐up regarding five public stigma domains: social distance, stereotyping, separateness, social restriction and perceived recovery. Both videos present individual narratives using different approaches: the self‐stigma video was created through focus groups, while the public stigma video portrays a single person's journey.ResultsA 3 × 3 analysis of variance (ANOVA) revealed a significant group‐by‐time interaction across all five stigma‐related domains (p's < .001). Effect sizes (Cohen's d) ranged from 0.29 to 0.52 (baseline to post‐intervention), and 0.18 to 0.45 (baseline to 30‐day follow‐up). The two video interventions did not significantly differ. Linear mixed modelling showed a significant difference between participants familiar and unfamiliar with people living with SMI for the public stigma video, with greater stigma reductions for unfamiliar participants.ConclusionsThis study corroborates previous findings on the positive influence of social contact‐based interventions on youth mental health perceptions. Results provide insights into the relationship between public and self‐stigma and the impact that familiarity with SMI may have on the efficacy of stigma reduction efforts further validation in diverse groups is needed.