bluuebunny/crossref_metadata_2025_split huggingface dataset:
Total Hip Replacement:The Preoperative Health Status of Patients in Japan Compared with England and the United States
Authors: Imamura Kyoko , Black Nick A. 
Published: March 2009

AbstractTo explore the contribution of health care to the excellent health status enjoyed by the Japanese compared with other industrialized populations, the preoperative health status of a retrospective cohort of 256 patients who underwent total hip replacement in Japan was compared with 301 patients in England (and published data from the United States). Patients in Japan had less severe hip disease, less comorbidity (in particular, less cardiovascular disease), and were in better general health. This finding suggests that health care contributes little to explaining the better health of people in Japan compared with England and the United States.
Healthy Years Equivalents Versus Time Trade-off: Ambiguity on Certainty and Uncertainty
Authors: Rittenhouse Brian E. 
Published: March 2009

AbstractPreference assessment literature has debated the equivalence of the healthy years equivalents (HYE) and time trade-off (TTO) methods. The central issue is whether the HYE measures preferences under uncertainty. This work shows that the two stages of the HYE first add and then remove the element of uncertainty so that ultimately the technique does not measure preferences under uncertainty. This makes the HYE, at best, a cumbersome equivalent of the TTO.
The Effects of Health Insurance on Access to New Medical Technologies
Authors: Ramsey Scott D. , Hillman Alan L. , Pauly Mark V. 
Published: March 2009

AbstractWe examined the use of percutaneous transluminal coronary angioplasty, kidney stone lithotripsy, and bone marrow transplant among patients with different health insurance plans in California. HMO enrollees were less likely to receive these procedures compared with fee-for-service patients. Our results have implications for the inflationary effects of technology under managed care.
Empowering Individuals in the Prevention of Genetic Disease
Authors: Pauker Susan P. 
Published: March 2009

AbstractAs the International Human Genome Project nears the term of a long gestation, the ethical and social implications of complex new genetic technologies will require a new breed of clinicians for a safe delivery. Clinical genetic care has been time intensive as performed by medical specialists. Empowering individuals to take advantage of new opportunities for genetic testing to prevent disease will require clinician education and decision support in the context of individual values.
Consensus Among Experts and Research Synthesis: A Comparison of Methods
Authors: Wortman Paul M. , Smyth Joshua M. , Langenbrunner John C. , Yeaton William H. 
Published: March 2009

AbstractA comparison of two assessment methods, consensus among experts and research synthesis of the scientific literature, was performed using a surgical procedure, carotid endarterectomy (CE), as an example. These two methods have been widely advocated as being scientifically valid. While the comparison revealed a number of areas of general agreement, important differences between the two methods emerged. For example, 30-day mortality for asymptomatic patients was considered an effective outcome (ranked first) by the synthesis, but only “quivocal” (ranked third) of six major indicators reported by the consensus method. The synthesis results are also consistent with other literature reviews as well as with recent large-scale randomized trial results. A number of factors that could account for differences between the two methods were examined. Overall, use of consensus panels may be appropriate early in the development of an intervention where the evidence is sparse, while quantitative research synthesis is preferable when a number of high-quality studies have been performed.
Evaluation of Benefits Related to Reduced Length of Stays in Postanesthesia Care Units
Authors: Tibi-lévy Yaël , De Pouvourville Gérard , Rozenholc Yves , Goursot Georges , Clergue François , Délémontey Bernard , Feiss Pierre , Laxenaire Marie-Claire , Marty Jean , Béresniak Ariel 
Published: March 2009

AbstractThe study's purpose was to estimate the potential economic benefit of the optimization of postanesthesia care units (PACUs). A simulation model was designed and used to test the economic impact of a reduction of length of stay. For the studied PACU, a reduction of 25% of length of stay is required to yield significant economic results.
Assessment of the Maximum Waiting Time Guarantee for Cataract Surgery: The Case of a Swedish Policy
Authors: Hanning Marianne , Lundström Mats 
Published: March 2009

AbstractCataract is the most common reason for visual problems in old age. The introduction of intraocular lens (IOL) implantation revolutionized cataract surgery. Since the IOL technique was established in Sweden in the early 1980s, the demand for surgery has been increasing, leading to lengthy waiting lists. To shorten some of the most troublesome waiting lists, national and local governments (county councils) in Sweden introduced a maximum waiting time guarantee in 1992. The assessment of the guarantee made in this article shows that ophthalmic surgery units vary in their adoption of the guarantee, leading to different levels of goal achievement in waiting times for their patients. The less successful units could be divided into two groups: one where the units have a low operation rate, and one where the units chose not to follow the recommendations in priority setting made in the guarantee.
Psychiatric Interventions for Prevention of Mental Disorders: A Psychosocial Perspective
Authors: Dalgard Odd Steffen , Sørensen Tom , Sandanger Inger , Brevik John Ivar 
Published: March 2009

AbstractTechnology for psychiatric prevention is poorly developed, and knowledge about the causes of mental Illness is difficult to apply to practical preventive work. As it would take many years before the effects of primary preventive efforts would be visible, secondary and tertiary prevention are essential to reducing the prevalence of mental illness. Recent studies on reducing the negative health consequences of acute stress seem to justify some optimism that psychosocially-oriented prevention is possible. Experience with the preventive benefits of social support at times of crisis suggests that active social support can prevent social disintegration at the community level and mental health problems for individuals.
Economic Incentives and the Distribution of Extracorporeal Shock wave Lithotripters and Linear Accelerators in Spain
Authors: Lázaro Pablo , Fitch Kathryn 
Published: March 2009

AbstractWe studied the role of economic incentives for private providers in explaining Spain's disproportionately large number of extracorporeal shock wave lithotripters (ESWLs) and low number of linear accelerators (linacs) per million population (pmp) in comparison to other countries of the Organization for Economic Cooperation and Development (OECD). We found that the reimbursement policy for 1990 allowed an average profit per private ESWL of $732,000, but no profit for linacs. Regional per-capita income was positively correlated with ESWLs pmp in Spain (R2 = 0.49; p =.001), but not with linacs. Sixty-nine percent of ESWLs were privately held versus only 16% of linacs. To avoid these types of distortions, financial incentives should be based on a reasonable relationship between cost and charges and should be associated with the appropriateness of medical care.
Cost-Effectiveness Analysis of Treatment for Esophageal Varices in Japan
Authors: Sasaki Akira , Eisenberg John M. 
Published: March 2009

AbstractWe analyzed the cost-effectiveness of nonemergent treatment for esophageal varices commonly used in Japan (endoscopic injection sclerotherapy, nonshunting direct interruption procedure, and selective shunt). We assessed the cost per survivor from the perspective of the Japanese government and other payors. Epidemiologic and economic data from published Japanese literature and from Japanese hospital-cost information were applied in decision analysis. While sclerotherapy is the most cost-effective treatment, the popular surgical procedures save the most lives, thus raising difficult ethical issues regarding trade-offs of cost and quality.
The Role of Pilot Studies in the Economic Evaluation of Health Technologies
Authors: Drummond Michael , Coyle Douglas 
Published: March 2009

AbstractAn increasing number of economic evaluations are being conducted alongside clinical trials. While this practice offers the prospect of collecting comprehensive and accurate cost data, it requires considerable time and effort. In the case of clinical data, key analytic decisions such as which data to collect and sample size are often made with reference to smaller (pilot) trials. However, this approach is not normally followed in the case of economic evaluation.This study was based on a recently completed health technology assessment comparing conventional radiotherapy with continuous hyperfractionated accelerated radiotherapy (CHART) for patients with head and neck cancer or carcinoma of the bronchus. In the full health technology assessment, cost data were available for 526 head and neck patients (314 CHART and 212 conventional therapy) and 286 bronchus patients (175 CHART and 109 conventional therapy). In order to simulate a pilot study, data were extracted for the patients recruited to both trials in the first 3 months. These were then compared with the full data set in order to assess whether such a pilot study would have given useful guidance on: a) the usefulness of undertaking a full study; b) the sample size required; and c) the important resource items for which comprehensive data collection would be required.Pilot studies can be helpful in determining the likely advantages of undertaking full economic evaluations and in identifying important resource items. Therefore, it is important that clinical researchers and research funding bodies create the necessary time window to enable such studies to take place. However, formal sample size calculations are more difficult to perform on limited data, since they also require knowledge of the unit cost (or prices) to be attached to the resource items and the correlation between costs and clinical effects.
Generalizing Costs from Trials: Analyzing Center Selection Bias in a Breast Screening Trial
Authors: Johnston Katharine , Gerard Karen , Brown Jackie 
Published: March 2009

AbstractWith a growing number of economic evaluations being conducted alongside trials, there is a need to address, and if necessary, investigate the generalizability of results derived from trials. This paper explores the generalizability of costs from a trial investigating the frequency of breast cancer screening in the United Kingdom.
The Cost-Effectiveness of Octreotide Acetate in the Treatment of Carcinoid Syndrome and Vipoma
Authors: Schonfeld Warren H. , Elkin Eric P. , Woltering Eugene A. , Modlin Irvin M. , Anthony Lowell , Villa Kathleen F. , Zagari Martin 
Published: March 2009

AbstractMarkov modeling was used to evaluate the cost-effectiveness of octreotide in treating carcinoid syndrome and VIPoma. For each condition, using octreotide was associated with doubled survival time. Octreotide was cost-effective for treating carcinoid tumor ($752 per additional year of life, two additional years on average), and cost saving for VIPoma.
The Costs and Benefits of Primary Total Hip Replacement:How Likely Are New Prostheses To Be Cost-effective?
Authors: Briggs Andrew , Sculpher Mark , Britton Annie , Murray David , Fitzpatrick Ray 
Published: March 2009

AbstractMany new hip prostheses are now available for use in total hip replacement. The majority remain untested relative to standard prostheses; however, many new prostheses are substantially more costly. We examine how much more effective new prostheses must be, in terms of reducing the need for revision operations, in order to justify this increased cost.
Medical Malpractice in Twentieth Century United States:The Interaction of Technology, Law, and Culture
Authors: De Ville Kennethe 
Published: March 2009

AbstractAlthough medical malpractice litigation in the United States has generated extensive professional and scholarly attention, few analyses of the issue have explored its underlying causes. This essay develops and employs an historical framework to explain the late 20th century phenomenon and concludes that widespread medical malpractice suits are the result of a combination of short-term topical causes and long-term cultural changes that are ignored or left untouched by most reform efforts. Most importantly, however, the development and proliferation of new and improved medical technologies has played a pivotal role throughout the entire history of the litigation, an effect that has become most prominent and important in the last third of the 20th century.
The Use of Societal Criteria in Priority Setting for Health Technology Assessment in the Netherlands: Initial Experiences and Future Challenges
Authors: Oortwijn Wija J. , Vondeling Hindrik , Bouter Lex 
Published: March 2009

AbstractPriority setting for the evaluation of health technologies in the Netherlands is exclusively based on the scientific merits of individual research proposals. This process has not resulted in satisfactory allocation of resources. Therefore, societal criteria for setting priorities for health technology assessment have been proposed as an adjunct to scientific criteria. These societal criteria include the burden of disease, uncertainty about the (cost-)effectiveness of the intervention at issue, the potential benefits of the research project, and its potential impact on health care. To realize the full potential of this model for priority setting, a number of methodological issues need to be addressed. Joint efforts of researchers and policy makers in this field are necessary for future progress.
Fecal Occult Blood Tests: A Cost-effectiveness Analysis
Authors: Gyrd-Hansen Dorte 
Published: March 2009

AbstractA range of fecal occult blood tests are presently on the market and could potentially be used in population screening programs for the detection of colorectal neoplasms. This paper estimates the relative cost-effectiveness of alternative tests and concludes that the unhydrated Hemoccult II is the most cost-effective. However, the incremental costs per life-year of the HemeSelect test and the rehydrated Hemoccult II test are in line with incremental costs observed in breast cancer and cervical cancer programs.
A Cost-Utility Analysis of Abdominal Hysterectomy Versus Transcervical Endometrial Resection for the Surgical Treatment of Menorrhagia
Authors: Sculpher Mark 
Published: March 2009

AbstractMenorrhagia, or heavy regular menstrual bleeding, represents a major health burden to women. Trials comparing abdominal hysterectomy (AH) with transcervical resection of the endometrium (TCRE) for the condition have shown that, although the duration and severity of convalescence is less with TCRE, AH produces a permanent solution to heavy bleeding while TCRE fails in a proportion of women by 2 years. However, by 2 years, TCRE costs only 71% that of AH. This paper presents a cost-utility analysis to assess which procedure is more cost-effective overall. Under most plausible parameter values and on the basis of health state values elicited from a sample of women with menorrhagia, AH is likely to be considered more cost-effective than TCRE if purchasers are willing to pay an additional cost of at least £6,500 per extra quality-adjusted life-year generated by AH.
Smoking During Pregnancy: Pregnancy Risks and Socio-demographic Characteristics among Pregnant Smokers
Authors: Cnattingius Sven 
Published: March 2009

AbstractMaternal smoking during pregnancy is causally related to fetal growth retardation. Smoking more than doubles the risk for the birth of a small-for-gestational-age infant. About 30% of the Swedish pregnant population smoke in early pregnancy. Despite that practically all pregnant women in Sweden today are aware of the hazards of smoking, about 70% of the smokers continue to smoke during pregnancy. Women who continue to smoke during pregnancy differ in terms of socio-demographic characteristics from those who stop smoking during pregnancy.
Prediction of Fetal Growth Deviations by Use of Symphysis-Fundus Height Measurements
Authors: Jacobsen Geir 
Published: March 2009

AbstractThe development of various symphysis fundus (SF) growth charts and the use of SF height measurements in the diagnosis of small-for-gestational-age (SGA) births and the prediction of newborn complications are reviewed. Measurement precision and accuracy are also discussed. It is concluded that further research of this simple, low cost, harmless, and widespread technology to detect fetal growth disturbances in routine prenatal care is warranted.
Detection of Intrauterine Growth Deviation:A Comparison between Symphysis-Fundus Height and Ultrasonic Measurements
Authors: Jacobsen Geir 
Published: March 2009

AbstractEfficacy of ultrasonography to detect fetal growth retardation is reviewed. Ultrasound dating is held as a prerequisite. Abdominal anthropometry is reported to reflect fetal growth best. Efficacy of symphysis-fundus (SF) height measurements is reviewed similarly. Proposed protocols that include ultrasound and SF height measurements and other maternal characteristics with known prognostic properties are reported. Preferably, both kinds of measurements should be analyzed longitudinally.
The Prognostic Significance of Antenatal Diagnosis of Fetal Growth Retardation
Authors: Leijon Ingemar 
Published: March 2009

AbstractIntrauterine growth retardation is associated with high risk of perinatal asphyxia. The neonatal mortality rate of small-for-gestational-age (SGA) infants (birthweight ≤ 2 SD) in Sweden decreased from 5.6% in 1973 to 2.0% in 1987. During the same period, the number SGA infants with postnatal asphyxia (5 min Apgar score <7) decreased from 10% to 5%. Based on antenatal diagnosis of fetal growth retardation, an optimal time of delivery reduces the risk of major neurological and developmental sequelae of the individual infant.
On the Asymptotic Behavior of Least-Squares Estimators in AR Time Series with Roots Near the Unit Circle
Authors: Jeganathan P. 
Published: March 2009

Some asymptotic properties of the least-squares estimator of the parameters of an AR model of order p, p ≥ 1, are studied when the roots of the characteristic polynomial of the given AR model are on or near the unit circle. Specifically, the convergence in distribution is established and the corresponding limiting random variables are represented in terms of functionals of suitable Brownian motions.Further, the preceding convergence in distribution is strengthened to that of convergence uniformly over all Borel subsets. It is indicated that the method employed for this purpose has the potential of being applicable in the wider context of obtaining suitable asymptotic expansions of the distributions of leastsquares estimators.
Professor Michio Hatanaka
Authors: Maekawa Koichi , Tanaka Katsuto 
Published: March 2009

This interview with Michio Hatanaka is the first in this series given in the East, of which we are very proud. Hatanaka is a pioneer of econometrics in Japan. In the early 1950s he traveled to the United States to study as a graduate student at Vanderbilt University. That step was really unusual in the Japanese profession at that time. His stay in the States was extended to 1966, during which time he taught at Princeton and Rochester. His pathfinding behavior influenced and encouraged many Japanese scholars. Hatanaka started his academic career as a mathematical economist. This may partly explain why his research papers suggest deep economic thought as well as deep understanding of mathematics and statistics. His early contributions to econometrics are concerned with applying the spectral method to various economic problems. These contributions include the associate authorship of Spectral Analysis of Economic Time Series by C. W. J. Granger. His other contributions cover theoretical work on identification and estimation problems for dynamic econometric models, among which Hatanaka's efficient two-step estimator is well known. His research also includes empirical work on the Japanese economy and economic policy, which is relatively less known to people outside of Japan. His attitude toward research has set a standard for Japanese econometricians. His research papers are always a product of deep and full thought, and imbued with his own originality.His achievements in administration are also impressive. During 1969–1971 and 1979–1980, he was director of the Institute of Social and Economic Research of Osaka University. And during 1983–1985 he was the dean of the faculty of economics at the same university. In addition, he served on the boards of several committees for the Japanese government and the Council of Science of Japan. Among his achievements in administration is the reform of the university entrance examination system, which was notoriously competitive and selective. This was really pathbreaking and led other universities to reform their systems.This interview, which was given in Japanese, took place on November 20, 1989 in the Economics Department of Osaka University. What follows is a translated version of an edited transcript of that interview. We hope that the readers will share with us the privilege of hearing about the evolution of econometrics as encountered by him since just after the second world war.
Causality in the Long Run
Authors: Clive W.J. , Lin Jin-Lung 
Published: March 2009

The definition of causation, discussed in Granger (1980) and elsewhere, has been widely applied in economics and in other disciplines. For this definition, a seriesytis said to causext+lif it contains information about the forecastability forxt+lcontained nowhere else in some large information set, which includesxt−j,j≥ 0. However, it would be convenient to think of causality being different in extent or direction at seasonal or low frequencies, say, than at other frequencies. The fact that a stationary series is effectively the (uncountably infinite) sum of uncorrelated components, each of which is associated with a single frequency, or a narrow frequency band, introduces the possibility that the full causal relationship can be decomposed by frequency. This is known as the Wiener decomposition or the spectral decomposition of the series, as discussed by Hannan (1970). For any seriesgenerated by, wherext, andare both stationary, with finite variances anda(B) is a backward filterwithBthe backward operator, there is a simple, well-known relationship between the spectral decompositions of the two series.