bluuebunny/crossref_metadata_2025_split huggingface dataset:
Estimating COVID-19 lockdown effectiveness: Analysis of the 2020 Danish mink lockdown
Authors: Ege Florian 
Published: March 2024

Abstract

In late 2020 Denmark became the focus of the global efforts against the Covid-19 pandemic when reports of a mutated SARS-CoV-2 virus variant in the countries population of 17 million farmed mink appeared. Spillover infections between mink and humans were feared to threaten the efficacy of upcoming vaccines. In this study the ensuing short-lived yet stringent lockdowns imposed in 7 of the countries 98 municipalities are analysed for their effectiveness to reduce SARS-CoV-2 infections. Synthetic counterfactuals are created for each of these municipalities using a weighted average combination of the the 91 municipalities not targeted by the stringent measures. This allows for a clear overview regarding the development of test-positivity rates, citizen mobility behaviours and lastly daily infection numbers in response to the restrictions. The findings show that these targeted, short-term lockdowns significantly curtailed further infections, demonstrating a marked decrease, first in citizens mobility and then in daily cases when compared to their synthetic counterfactuals. Overall, the estimates indicate average reductions to infection numbers to be around 31\%. This study underscores the potential of strict, yet severe lockdowns in breaking ongoing infection dynamics, by utilising a rare quasi-experimental design case that avoids endogeneity through treatment selection.
β-CPP bioceramics in alginate 3D Scaffolds as a new material for mineralized tissue regeneration
Authors: Pinto Gabriel C. , Piazza Rodolfo D. , Soares Igor P. Mendes , Anselmi Caroline , Coimbra Eduardo T. C. , Costa Carlos A. Souza , Hebling Josimeri , Silva Nuno J. O. , Guastaldi Antônio C. 
Published: March 2024

Abstract

In the pursuit of tailored properties for applied bioceramics in bone graft applications, a personalized mixture of precursor base materials is crucial. Hydroxyapatite (HA), beta tricalcium phosphate (β-TCP), and versatile biopolymers serve as base materials to produce personalized mixtures, each presenting its own set of advantages and disadvantages. Combining these materials addresses limitations of individual components, but further improvements require exploring alternative base materials with distinct properties. This study introduces beta calcium pyrophosphate (β-CPP) as a valuable addition to the base materials, exhibiting intermediate biodegradation properties. When combined with biopolymer alginate, β-CPP enables the fabrication of personalized porous 3D scaffolds. Despite β-CPP being an unwanted by-product in mineralized tissue regeneration, this research demonstrates its innovative potential in stimulating cell interaction within porous 3D structures. The β-CPP/Alginate 3D Scaffold, with a 5:3 w/w ratio, significantly enhances mineralization activity compared to the control. This novel composite, showcasing interconnected cells throughout the 3D structure, presents a promising avenue for mineralized tissue regeneration. The study underscores the importance of optimizing both biodegradation and mechanical features in new bioceramics, highlighting β-CPP as a noteworthy candidate with potential commercial implications.
Design of Magnetic κ-Carrageenan-Collagen Bioinks for 3D Bioprinting
Authors: Almeida Duarte , Küppers Freya , Gusmão Afonso , Manjua Ana C. , Ferreira Catarina F.R. , Portugal Carla A.M. , Silva João C. , Sanjuan-Alberte Paola , Ferreira Frederico Castelo 
Published: March 2024

Abstract
Bioprinting approaches are of great promise for tissue engineering (TE) applications, given that they allow the fabrication of constructs able to mimic native tissues' mechanical and topographical features. In this study, a novel bioink comprising κ-carrageenan (κc), collagen, and magnetic nanoparticles (MNPs) was designed for 3D bioprinting applications. κc is suitable for use in bioprinting due to its gelation and mechanical properties. Combining this polysaccharide with collagen and MNPs for remote stimulation of the printed scaffold, we successfully achieved a 3D-printed functional structure. Mechanical compressive tests yielded Young’s moduli ranging from 8.25 to 18.4 kPa. The addition of collagen caused this value to decrease, as expected, while the addition of MNPs had an opposing effect. The hydrogels also exhibited water contents over 97% in all formulations. Rheological assessments indicated a sol-gel transition temperature at 23-25ºC, making these bioinks suitable for extrusion-based bioprinting at room temperature. Printability analyses demonstrated excellent fidelity and structural integrity of the printed constructs, in addition to a high mesenchymal stem/stromal cell (MSC) viability after bioprinting. Finally, as proof-of-concept, it was observed that bioprinted MSCs stimulated with an external magnetic field of 80 mT were able to increase the number of tubes formed by human umbilical vein endothelial cells. In conclusion, this study constitutes a valuable approach for 3D bioprinting of multifunctional materials using novel bioink compositions, thus advancing TE technologies while creating new paths for future research in regenerative medicine applications.
Pregnant Women Perceived Community Acceptance for Deliveries attended by Traditional Birth attendants and its Correlates in Ethiopia: Community based longitudinal follow up Study
Authors: Damtew Solomon Abrha , Fantaye Fitsum Tariku , Sene Kelemua Menegesha 
Published: March 2024

Abstract
Background
World health organization (WHO) recommends that all child birth need to attend by professional skilled attendant who at least midwifery skill through the safe motherhood initiative. Many births in developing are being attended by Traditional birth attendants mainly due women and community acceptance of TBA as sole birth attendants. Therefore, measuring the women perceived community acceptance towards births attended by TBA and identifying factors provides evidence for policy makers, health program managers and health care practitioners in their effort to escalate skilled and facility delivery there by improving maternal and new born health outcome.
Methods
This study used PMA cohort 1 baseline data which enrolled and collected data from currently pregnant women. Frequency was computed to describe the study participant’s characteristics. Multinomial logistics regression was employed to identify correlates of perceived acceptance for births attended by TBA. Results were presented in the form percentages and odds ratio with 95% Confidence Intervals. Candidate variables were selected using p-value of 0.25. Statistical significance was declared at p-value of 0.05.
Results
One fourth, nearly one in five (18.27%) and 15.05% of the pregnant women reported few people, most and some people in their community think it’s acceptable to deliver with Traditional Birth Attendants (TBA) respectively. attending primary education increases the likelihood of women pregnant women perception that most people in their community thinks that it’s acceptable for deliveries to be attended by TBA. While pregnancy desire that women who intended to have another child have higher likelihood to perceive that few people in their community consider that its acceptable that deliveries to be attended by TBA. On the contrary, religion, residing in the well to HHs, residing in the former SNNP and Addis Ababa have lowered pregnant women perception that people (most, few and some) in their community considers that it’s acceptable for deliveries to be attended by TBA.
Conclusions
Substantially greater proportion of pregnant women reported that it’s acceptable to delivery for at least few people in their community which call on tremendous work to be done to avert such high level pregnant women acceptance that people in their community thinks births to be attended by TBAs. Activities targeting improving women economic status and empowerment; increasing women enrollment to secondary and higher education; using religious leaders and institutions to promote health service use and skilled delivery are likely to mitigate such huge surge of miss conception towards delivery care.
COVID-19 and educational resilience in Africa: How school closure revealed countries’ educational conditions
Authors: BECHE Emmanuel , SII Marie Pascale 
Published: March 2024

Abstract

This study examines school closures in Africa during the COVID-19 pandemic as a reflection of a country’s educational conditions. Using an interdisciplinary approach that combines the sociology of crisis and decision-making, it focuses on two leading indicators: the timing and duration of school closures concerning the emergence of the coronavirus. We then correlate these factors with each country’s specific pandemic and educational context. Our data collection involved an online documentary analysis and leveraged insights from two webinars on African responses to COVID-19, conducted in March and June 2020, in which we participated. Through a categorical analysis, we classify the 54 African nations into five groups according to how they handled school lockdowns during this pandemic: resistant, proactive, reactive, post-active, and passive, demonstrating that the modalities of their school closures were not neutral. Our analysis reveals the intricate complexities of the educational conditions in these countries, providing valuable insights into their crisis management policies and governance. It offers perspectives to assess educational resilience in major crises and deepens the relationship between educational conditions and responses to these crises.
In-silico Studies, Synthesis, and Antacid Activities of Magnesium (II)
Complexes
Authors: Jha Basuki Nath , Kothari Richa , Agrawal Anurag 
Published: March 2024

Background:
Nowadays, acidity is a severe problem worldwide caused by excessive
gastric acid secretion by the stomach and proximal intestine.

Objective:
Antacids are drugs capable of buffering stomach acid. Therefore, in our research work,
we have reported the in-silico studies, synthesis, characterization, and evaluation of antacid activities
of magnesium (II) complexes via the acid-base neutralization process.

Methods:
In this research, some magnesium complexes were synthesized and their antacid behavior
was compared with marketed products. Also, in-silico studies were performed on H+/K+
ATPase (Proton pump). All synthesized compounds were characterized by various spectroscopic
techniques like UV-Vis, FT-IR, XRD, and DSC techniques.

Result:
Spectroscopic analysis results showed that the semicarbazone ligand shows keto-enol
isomerism and forms a coordinated stable complex with magnesium ions in the crystalline phase.
The FT-IR results confirmed the presence of Mg-O stretching, N-H bending, and C=N stretching
vibrations in Mg (II) complexes.

Conclusion:
The antacid activities of Mg (II) complexes were excellent as compared to the semicarbazone
ligand and comparable with that of marketed antacid drugs like ENO, and Pantop-D. Insilco
studies also confirmed that semicarbazone ligand and its Mg (II) complexes were both found
to be fitted into the active sites of molecular targets, and Mg (II) complexes showed better binding
affinities towards macromolecular as compared to semicarbazone ligand.
Nutritional Potency of Mangifera indica L. (Mango): Focus on Mango as Antioxidant
Authors: Shah Bhargavi Vijay , Chopra Harsha , Medithi Srujana , Ungarala Venkat Ramakrishna 
Published: March 2024

Background:
Mango, known as "the king of fruits," is one of the most popular fruits on the planet. Vitamins, minerals, antioxidants, and bioactive substances abound.

Objective:
In the present review, we aimed to explore the therapeutic effects of mango as an antioxidant.

Methods:
Scopus and ScienceDirect databases were used to gather research papers over the pre-vious 12 years.

Results:
Our research explores the formidable antioxidant potential of mango, driven by its ele-vated phenolic and flavonoid content. Within mango, crucial metabolites such as glutathione and euxanthone contribute significantly to its antioxidant and anti-inflammatory prowess. A note-worthy bioactive compound, Mangiferin, found in mango, exhibits anti-diabetic properties by inhibiting sucrase and isomaltase, consequently reducing glucose absorption in the intestine.

Conclusion:
In our study, mango has demonstrated its ability to lower blood sugar levels, en-hance insulin production, and reduce lipid levels. These beneficial effects are attributed to high soluble fiber, polyphenols, and carotenoids, including quercetin and beta-carotene. Our findings shed light on the multifaceted health-promoting attributes of mango, positioning it as a valuable natural resource for potential dietary interventions and health enhancement. In conclusion, ef-fective blood sugar management hinges on strategic dietary decisions. Steering clear of high-glycemic combinations with mangoes, choosing daytime consumption, and integrating regular physical activity for energy equilibrium is paramount.
Sex, physical activity, obesity, and hypercholesterolemia in millennial workers of X Corp, Jakarta, Indonesia, in 2023
Authors: Yusvita Fierdania , Nandra Nadya Shinta 
Published: March 2024

Purpose: This study aims to analyze the relationship between sex and sedentary behavior and obesity and its impact on hypercholesterolemia in millennial generation workers at X Corp., Jakarta, Indonesia, in 2023.
Methods: This research is an observational analytic study conducted on 269 millennial workers at X Corp. The data collection used was the results of X Corp’s worker's medical check-ups. Data processing using the Chi-square test to see whether there’s a linkage between the research variables.
Results: From the tables, there is a correlation found between sex and obesity (p=0.001); there is no correlation found between physical activity (p=0.105) and smoking behavior (p=1.000). There is a correlation between obesity and hypercholesterolemia (p=0.004) in millennial workers at X Corp.
Conclusions: Unhealthy life behaviors can be a risk factor for health problems, including degenerative diseases, as millennial workers get older. Male workers are more at risk of being obese and having an impact on the emergence of hypercholesterolemia and the risk of diabetes mellitus if a healthy lifestyle is continuously neglected. It is suggested that the application of occupational health promotion at X Corp., Jakarta, Indonesia, can be further optimized.
Regional disparity in age-related disability: toward healthy aging in Indonesia
Authors: Puspitasari Mardiana Dwi , Rahardja Mugia Bayu , Nurhayati Septi , Surbakti Indra Murty 
Published: March 2024

Purpose: Maintaining functional ability and minimizing age-related disability of older adults are required to promote healthy aging. A supportive physical and social environment, in addition to individual variables, has a role in reducing the risk of age-related disability. Infrastructure development differs between Java-Bali and outer Java-Bali regions. This study aims to determine the extent to which the disability of older adults in Java-Bali and outer Java-Bali regions.
Methods: This study is cross-sectional, using data from the 2020 National Socio-Economic Survey (SUSENAS) with 122.344 Indonesian older adults aged 60 and over. Disability is the outcome variable. The explanatory variable is regional disparity (Java-Bali and outer Java-Bali regions), which refers to where the older adults live. In addition, the control variables include age, sex, marital status, educational level, employment status, leisure activity, household wealth status, and self-rated health status (SRHS). A multivariate logistic regression statistical analysis is performed.
Results: The outer Java-Bali region has a slightly greater prevalence of older adults with age-related disability than the Java-Bali region, with 28.8 and 22.9 percent, respectively. However, older adults living in the outer Java-Bali region are 1.63 times more likely (OR 1.63; 95% CI (1.58-1.68)) to have disability than those living in the Java-Bali region. Other socio-demographic variables are significantly associated with age-related disability.
Conclusion: Living in the Java-Bali region increases the risk of age-related disability. Infrastructure development in the outer Java-Bali region needs to be improved so that older adults can experience healthy aging.
Analysis physical workload, mental workload, and work stress on teachers at Public Special School of Surakarta
Authors: Pitaloka Fitri Rahmawati Dyah , Widowati Evi 
Published: March 2024

Purpose: This study aimed to analyze the relationship between physical workload and mental workload towards work stress on special school teachers. In addition, it discovers the portrayal of the level of physical and mental workload and work stress.
Methods: This study is a quantitative research through a cross-sectional approach. A total of 50 teachers was the sample. Variables in this study were physical workload, mental workload, and work stress. Data was collected with a pulse oximeter and questionnaires of NASA-TLX and PSS-10, and collected data was analyzed with the Spearman rank test.
Results: The results of this study showed there is no relationship between physical workload and work stress. On the other hand, there is a relationship between mental workload and work stress (p-value=0.720; PR=0.762). Furthermore, 18% of teachers had a required improvement in physical workload, 12% had a very high mental workload, and 50% had moderate work stress (p-value=0.000; PR=0.552).
Conclusions: This study indicated that there is no relationship between physical workload and work stress, in the other hand, there is a relationship between mental workload and work stress.
Spatial analysis of rabies-transmitting animal bite cases in North Tapanuli Regency, North Sumatera Province in 2016-2020
Authors: Simanjuntak Saidah Fatimah Sari , Sipahutar Tiopan , Mafkul Martya Rahmaniati 
Published: March 2024

Purpose: Rabies is a priority strategic disease because it has an impact on socio-economic and public health. This study aims to describe the incidence of rabies-transmitting animal bite cases in North Tapanuli Regency in 2016-2020, contribute to understanding the dynamics of cases, and provide effective information in controlling cases of animal bites that transmit rabies.
Methods: Ecological study using aggregated data. The data was collected from monthly reports of rabies cases at the North Tapanuli Regency Health Service in 2016-2020. As a unit analysis, all districts are used. QGIS and GeoDA software are used for data analysis. Through GeOda software, spatial autocorrelation analysis was carried out globally using Moran's I test and locally using the LISA test.
Results: Rabies-transmitting animal bite cases had a dispersed pattern in 2016 (I<E[I]) and a clustered pattern (I>E[I]). Globally, there is positive spatial autocorrelation in rabies-transmitting animal bite cases between districts in North Tapanuli Regency in 2017 and 2020 (p-value < 0.05). Moran's cluster map shows that locally in 2016-2020, the districts in the quadrant I (High-High) are Siborongborong and Sipoholon. Quadrant II (Low-High) is Adiankoting and Pagaran. Quadrant III (Low-Low) is Pangaribuan, and quadrant IV (High-Low) is Pahae Jae and Pangaribuan.
Conclusion: Globally, cases of animal bites that transmit rabies in North Tapanuli Regency occur in clusters. It means that the number of bite cases in one area is related to the number of cases in other nearby areas. Therefore, rabies control program interventions in areas with high observation values must be prioritized so they do not spread to areas with low observation values.
Senyawa Sitotoksik dari Fraksi Diklorometana Daun Pandan Wangi (Pandanus amaryllifolius Roxb.) Terhadap Sel Kanker Payudara T47D
Authors: Angelia Sharon , Harlia Harlia , Widiyantoro Ari 
Published: March 2024

Kanker payudara merupakan salah satu penyakit mematikan di dunia pada wanita. Terapi dengan suatu agen kemoterapi belum memberikan penyembuhan yang optimal sehingga menyebabkan terjadi kerusakan jaringan sehat maka diperlukan pengobatan berbasis bahan alam dari tumbuhan yang berpotensi sebagai antikanker yaitu daun pandan wangi (Pandanus amaryllifolius Roxb.). Penelitian ini dilakukan untuk menentukan aktivitas sitotoksik dan mengetahui karakteristik isolat dari fraksi diklorometana. Penelitian ini dilakukan dengan beberapa tahapan meliputi maserasi, partisi, dan kromatografi. Hasil penelitian menunjukkan isolat dari fraksi diklorometana mempunyai aktivitas sitotoksik terhadap sel kanker payudara T47D dengan nilai IC50 sebesar 137,32 Âµg/mL. Isolat dari fraksi diklorometana dengan analisis 1H-NMR (DMSO, 500 MHz) diprediksi merupakan golongan alkaloid kerangka pirolidin dengan pergeseran kimia menunjukkan adanya Î´HÂ 8,08 ppm (1H,s), 7,68 ppm (5H, dd, J=3,6 Hz, 5,6 Hz), 4,22 ppm (6H, dd, J=3,6 Hz, 5,4 Hz), 3,57 ppm (9H, d, J= 9 Hz), 3,16 ppm (3H, s), 2,63 ppm (2H, s), 2,36 ppm (2H,s), 2,27 ppm (2H, s), 2,08 ppm (1H, s), 1,83 ppm (1H,s), 1,66 ppm (8H, m), 1,30 (28H, m) dan 0,81 (17H, m).
Pengaruh Dinding Bata terhadap Kapasitas Seismik Gedung Beton Bertulang Berlantai Banyak
Authors: Leilany Lili , Tanjung Jafril , Sunaryati Jati 
Published: March 2024

Studi ini menjelaskan tentang pengaruh dinding bata terhadap kapasitas seismik gedung beton bertulang. Di kota Padang, dinding bata digunakan sebagai dinding non struktural pada sebagian besar gedung beton bertulang. Dalam hal ini, kontribusi dinding bata terhadap kinerja struktur gedung bertulang dianalisis. Bangunan beton bertulang sepuluh lantai dipilih sebagai model dalam penelitian ini yang bertujuan untuk mengetahui kapasitas seismik dan keamanan gedung ditinjau dari perpindahan, drift rasio, dan gaya geser dasar. Untuk mengevaluasi kapasitas seismik gedung beton bertulang digunakan 2 (dua) model. Bangunan dianalisis dan dibandingkan antara bangunan beton bertulang dengan dan tanpa dinding bata. Pemodelan dianalisa dengan menggunakan Push Over Analysis dengan menggunakan software yang disebut Struktural Earthquake Response Analysis 3D (STERA 3D), Analisis Pushover dilakukan dengan menggunakan distribusi beban UBC. Hasil analisis menunjukkan bahwa dinding dalam rangka beton bertulang dapat meningkatkan gaya geser dasar sekitar 38% dan 25% pada arah X dan Y struktur dibandingkan dengan rangka beton bertulang tanpa dinding bata, dinding bata juga dapat meningkatkan titik kinerja dalam arah X dan Y struktur masing-masing sebesar 45% dan 32%. Dinding bata dapat mengurangi kerusakan pada komponen struktural. Dapat disimpulkan bahwa penggunaan dinding bata dapat memberikan peningkatan terhadap kapasitas seismik bangunan beton bertulang secara signifikan.
KEMAMPUAN PESERTA DIDIK DALAM MEMBUAT MIND MAPPING PADA PEMBELAJARAN MATEMATIKA
Authors: . Eminatri 
Published: March 2024

Taking notes are important activities that students need to do while following the mathematics learning process. The notes will be useful to them as relevant guidelines to help complete the task or prepare for the exam. However, many learners do not take notes in mathematics learning. This is due to their lack of awareness of the benefits of notes in learning. One of the tips that can be done to overcome this is to take notes with mind mapping techniques. Mind mapping is a way of recording creatively, effectively and not boringly because in making it students are facilitated to express their thoughts / abilities and imagination to use various newly learned words / terms, symbols / images, and colors, so that the ideas mapped will last a long time in their memory. This is different from ordinary notes that are only in the form of narratives. This research has facilitated class XI mipa students of SMAN 8 Padang to make notes with mind mapping techniques. As a result, the ability to make mathematical mind mapping for students is in the sufficient category. Keywords– Mind Mapping, Mathematics Learning.