bluuebunny/crossref_metadata_2025_split huggingface dataset:
Rosa roxburghii Tratt Residue Can be Used as a Novel Feed Resource for Cattle
Authors: Song Xinyu , Yang Yi , Wang Chong , Zhu Wen , Wu Wenxuan 
Published: April 2024

Abstract
Rosa roxburghii tratt residue (RRTR) is a regional and uncommon byproduct in Guizhou. Little information is available on whether RRTR can be used as feed for ruminants. In this study, the feasibility of using RRTR as a new feed resource for cattle was investigated by chemical composition analysis, in vitrogas production(Trial 1) and animal feeding experiments (Trial 2). In trial 1, compared to the commonly used fruit residues, RRTR had a medium proximate nutrientlevel; the in vitro gas production at 24 h (166.67 mL) and dynamics fellwithin the normal range. In trial 2, 16 cattle were allocated to the control and treatment groups,with 8 replicates of 1 cattle each. Cattle in the control group were fed a basal diet without RRTR,while those in the treatment group were fed a diet containing 30% RRTR. Feeding RRTR had little effect on the growth performance of the control and treatment cattle (P>0.05). The feed-to-gain ratio was greaterin the treatment group than in the control group throughout the trial period (P<0.05). Compared with those in the control group, the plasma urea levels in the treatment group were lower (P<0.05), and the levels of other plasma biochemical metabolites were not differentbetween the two groups of cattle (P>0.05). The in vivo rumen fermentation parameters did not differ between thecontrol and treatment groups (P>0.05). Our findings indicate that RRTR has a nutritional profile similar to that ofcommonly used fruit residues; improves plasma protein utilization efficiency; and has little negative impact on growth performance, blood metabolites, and rumen fermentation parameters in cattle. Accordingly, RRTR can serve as a novel feed resource for cattle.
Logarithmic vanishing theorems on Weakly 1-complete Kahler manifolds
Authors: Lu Shilong 
Published: April 2024

Abstract

In this paper, we prove a logarithmic vanishing theorem on weakly $1$-complete k\"ahler manifold, which is a generalization of Huang-Liu-Wan-Yang's result on compact k\"ahler manifold. We first briefly introduce the local case of the theorem, which can be obtained as a corollary of the compact k\"ahler case. Next, we prove the global case of the theorem. The difficulty here is how to find a continuous solution $\psi$ from a sequence ${\psi_v}$ of discrete solutions of equation $\varphi_v=\bar\partial\psi_v$, such that for each $v\in \mathbb{R}$, $\varphi_v=\bar\partial\psi$. In this paper, the continuous solution is given by using the approximation theorem.
2020 Mathematics Subject Classification. 32Q15,14F17.
Use of antipsychotic drugs during radiotherapy in adult cancer patients in Korea: A nationwide retrospective cohort study based on the health insurance review and assessment service database
Authors: Hwang In Gyu , Park Song E , Kim Sun Mi , Kang Dae Ryong , Go Tae-Hwa , Hong Se Hwa , Ha Yong-Chan , Park Shin Young , Lee Hyunho , Choi Jin Hwa 
Published: April 2024

Abstract

Background
Antipsychotic drugs (APDs) are used for treating mental illnesses and are also used by cancer patients. This study aimed to evaluate APD use in adult cancer patients who received radiotherapy (RT) in South Korea and assess the effects of APD use during RT on survival.
Methods
This retrospective cohort study utilized the Health Insurance Review and Assessment Service database of Korea. We included adult cancer patients who underwent RT or chemotherapy (CTx, cisplatin, or 5-Fluorouracil) between 2010 and 2020. The APDs included in the analysis were aripiprazole, quetiapine, olanzapine, risperidone, haloperidol, and chlorpromazine.
Results
Overall, 725,897 patients received RT, and 115,500 received concomitant chemo-radiotherapy (CCRT). Of them, 41,118 (5.6%) took APDs during RT, and 8,129 (7%) took APDs during CCRT. Overall, 27,789 (67.58%) patients who took APDs during RT were men, and 28,004 (68.2%) were aged ≥ 60 years. The most frequently used APD during RT was quetiapine (64.93%). The three cancer sites with the highest frequency of APD users during RT were the lungs (21.64%), breast (5.09%), and colorectum (4.44%). The three cancer sites with a high proportion of APD use during RT were the lungs (14.87%), brain (14.27%), and esophagus (12.95%). Patients who took APDs during RT had a higher mortality rate (HR: 3.45, p < 0.0001) compared to the non-APD patients. The patients taking high-dose APD had a lower mortality rate than those on low-dose APD (HR: 3.23 vs. 3.46, p < 0.0001).
Conclusions
Only 5.6% of patients who underwent RT used APDs, and quetiapine was the most frequently prescribed APD during RT. Patients who used APDs during RT had poorer survival than those who did not. Further studies are required to elucidate the effects of APDs on cancer patients.
Trial registration:
This study is retrospectively registered
Dehydration of Turbine Engine Lubricant Oil Using Cellulose Hydrogel
Authors: Estevam Bianca Ramos , Perez Isadora Dias , Tsuruta Karina Mayumi , Neto Roberto Mendes Finzi , Mancuzo Mechelangelo Viana , Cavallini Aldemir Aparecido , Moraes Ângela Maria , Fregolente Leonardo Vasconcelos 
Published: April 2024

Abstract
Contamination of oils by water is a recurring problem in the industry and can damage engines and equipment. Oil dehydration systems with hydrogels have shown promise for the removal of free, soluble, and emulsified water. This work evaluates, in an unprecedented way, the dehydration of turbine lubricating oil using a cellulose hydrogel. The hydrophilic polymer was characterized through high-resolution SEM, EDS, FTIR, BET, TGA, DVS and swelling degree. The oil was evaluated regarding its composition and physicochemical properties. The performance of the hydrogel in the treatment of water-in-oil emulsion was analyzed in batch and continuous flow systems. A fixed bed apparatus was specially designed and sized according to the industry's specifications to simulate on-site application. The batch treatment was evaluated using orbital and full tumbling inversion mixing systems, both reaching removal efficiency of around 47%. Mixing by full tumbling allowed greater stability of the emulsion and control of the water concentration, but it required a longer time to enable adequate water uptake by the hydrogel. The efficiency of the hydrogel in the continuous flow system was affected by retention time and inlet water concentration. With a retention time of 12 min, it was possible to treat 1 L of oil, reducing the water concentration from 412 ppm to 197 ppm and the turbidity from Haze 6 to Haze 1. Thus, the cellulose hydrogel was efficient in dehydrating turbine lubricating oil, opening up the possibility of expanding its use to industrial facilities.
Prevalence and clinical correlates of anxiety symptoms in first-episode and drug-naïve major depressive disorder patients with dyslipidemia at different ages of onset: a large cross-sectional study
Authors: Wang Guanjun , Liu Yanting , Ji Yunxin , Wang Kuilai , Lang xiaoe , Zhang Xiang 
Published: April 2024

Abstract
Background
Major depressive disorder (MDD) patients often have different clinical manifestations at different age of onset. Anxiety symptoms are frequently seen in patients with MDD, and dyslipidemia is also prevalent in these populations. There is limited reporting on the frequency of anxiety symptoms and their associations with clinical factors in patients with abnormal lipid metabolism who have MDD.
Methods
Our study included 1718 first-episode untreated MDD outpatients aged 18–60 years, 1408 of whom had dyslipidemia. We collected basic information, clinically relevant data, and biochemical indicators from these patients. Anxiety, depression and psychiatric symptoms were evaluated by Hamilton Anxiety Scale (HAMA), Hamilton Depression Scale (HAMD) and Positive and Negative Syndrome Scale (PANSS) positive subscale, respectively.
Results
Anxiety symptoms were found in 57.8% of depressed outpatients with dyslipidemia, a rate significantly higher than in MDD patients with normal lipid levels. No statistical difference was observed in the prevalence of anxiety symptoms between the early adulthood onset (EAO) group and mid-adulthood onset (MAO) group. Anxiety symptoms were significantly correlated with both HAMD and PANSS scores, regardless of the age of onset. Thyroid-stimulating hormone (TSH), total cholesterol (TC) levels and suicide attempts were independently associated with anxiety symptoms in the EAO group, whereas fasting blood glucose (FBG) was independently related to anxiety symptoms in the MAO group.
Conclusions
Our research findings indicated that the age of MDD onset in patients with dyslipidemia did not impact the presence of anxiety symptom. The clinical factors linked to anxiety symptoms varied between the EAO and MAO groups, potentially aiding in the prediction of anxiety symptoms in the specific population.
Computational investigation of phytochemicals from Allamanda cathartica as a potent agonist of Peroxisome proliferator-activated receptor-gamma (PPARγ) for the treatment of Diabetes mellitus
Authors: Tomar Ritu , Mishra Shashank , Sahoo Jagannath , Rath Santosh Kumar 
Published: April 2024

Abstract

Diabetes, a chronic metabolic disease, has become a serious health problem worldwide. According to the latest data from the International Diabetes Federation (IDF), there were 451 million DM patients worldwide in 2017, and would be expected to increase to 693 million by 2045. Therefore, there is a need to develop new drug-like molecules to combat this problem. Peroxisome proliferators-activated receptors (PPARs) are ligand-inducible nuclear receptors that control many intracellular metabolic processes. PPARγ agonists can improve metabolism and reduce the side effects caused by single drugs and have become a valuable drug target for designing effective drugs for the treatment of type 2 diabetes. In the present investigation, by the application of bioactivity score prediction, molecular docking, and ADMET prediction approach, the potential and selective phytoconstituents with the highest binding affinity, and lower toxicity than reference drug rosiglitazone was gained from the curated datasets of Allamanda cathartica. Further molecular dynamics simulations were carried out to identify the favourable binding conformations when the top-scored phytoconstituents bind with the PPARγ receptors compared to the rosiglitazone. Compound AC2 interacts with the PPARγ proteins through the formation of 7 hydrogen bonds with the amino acid residues Phe282, His449, Tyr327, His323 and Ser289. The ligand was bound to the protein during the simulation since none of the complexes conformations were unstable and no unfolding or folding took place. Our results provided an approach to further design and optimize the natural product-inspired small druglike molecules as potential antidiabetic agents. The present study highlighted that the phytoconstituents of Allamanda cathartica has antidiabetic potential as PPARγ agonists that can be further explored for novel antidiabetic drug development.
The Effect of High Ownership Concentration on Tax-Motivated Income Shifting : Evidence from North Africa Multinational Groups
Authors: soltani lynda 
Published: April 2024

Abstract

This paper focuses on multinational corporate groups that resort to income shifting motivated by tax evasion, measuring their association with high ownership concentration. In order to test our hypothesis, our sample is composed of parent companies located in north africa as well as subsidiaries with a lower tax rate than the parent company. The model is based on natural logarithm of pre-tax profit. The results show that parent companies with a high concentration of ownership transfer income for tax avoidance purposes. The result is that governments are reducing their statutory tax rates to encourage investors to focus on high concentration companies in order to increase economic growth. This study shows that, depending on their characteristics, entrepriques can practise tax avoidance strategies, with the emphasis on high levels of ownership concentration
Causal network localization of brain stimulation targets for trait anxiety
Authors: Siddiqi Shan , Klingbeil Julian , Webler Ryan , Kratter Ian , Blumberger Daniel , Fox Michael , George Mark , Grafman Jordan , Pascual-Leone Alvaro , Pines Andrew , Richardson R. Mark , Talati Pratik , Vila-Rodriguez Fidel , Downar Jonathan , Hershey Tamara , Black Kevin 
Published: April 2024

Abstract
Transcranial magnetic stimulation (TMS) and deep brain stimulation (DBS) can treat some neuropsychiatric disorders, but there is no consensus approach for identifying new targets. We localized causal circuit-based targets for anxiety that converged across multiple natural experiments. Lesions (n=451) and TMS sites (n=111) that modify anxiety mapped to a common normative brain circuit (r=0.68, p=0.01). In an independent dataset (n=300), individualized TMS site connectivity to this circuit predicted anxiety change (p=0.02). Subthalamic DBS sites overlapping the circuit caused more anxiety (n=74, p=0.006), thus demonstrating a network-level effect, as the circuit was derived without any subthalamic sites. The circuit was specific to trait versus state anxiety in datasets that measured both (p=0.003). Broadly, this illustrates a pathway for discovering novel circuit-based targets across neuropsychiatric disorders.
Factors affecting the willingness to pay for biogas digestor construction of pig farms in Champasak province Lao PDR
Authors: Fongsamouthb Salongxay , Moonphoxay Houmpheng , Phaxaisithidet Thanousinh , Sounakeovongsa Vilaphone , Homsombath Philavanh , Souvannasouk Vannasinh 
Published: April 2024

Abstract
This paper aims to estimate the environmental issue and policy recommendations for supporting biogas digestor construction. An environmental evaluation related to environmental protection and raising natural resources as renewable energy to persuasion policy applies to pig farms with the idea of building a biogas digestor. The main occupation of the household has a relationship in the same direction as the WTP, agricultural occupation as their main occupation, especially crop producing and feeding animals, be willing to pay more than the households that are engaged in other occupations because the households that are engaged in agricultural production have high expectations for the not only benefits producing biogas, but also high-quality compost that can be used for their crops producing as well. They are willing to pay more than others, especially in a situation where the price of chemical fertilizers is high like the current situation. The period of raising pigs (year) has a relationship in the opposite direction to the WTP, and households with increased periods of raising pigs have the opportunity to be willing to pay less with a statistical significance level of 90%. It may be because the number of pigs has a relationship in the same direction with WTP, according to the hypothesis, a household with an increase in the number of pigs in the farm has a chance to be willing to pay by 1.43% with a statistical confidence level of 99%.
A field study of manhole cover leakage
Authors: Lowe Scott 
Published: April 2024

ABSTRACT
Leaking manhole covers add inflow to sanitary sewer systems. These are the most accessible components of the sewer system, and so potentially the cheapest to repair or modify, to reduce inflow. There is, however, very little data regarding manhole cover leakage available to evaluate the cost–benefit of such an approach, and there is no field data. So, a multi-year field study of inflow was conducted. Two-hundred and fifty manholes in New York City and surrounding towns were tested. A key field observation in this study was that a dust and grit seal typically built up between the cover and the rim. This seal had a big impact on leakage rates. This made testing in-situ a necessity, and the test method had to preserve this seal. Due to the presence of the dust and grit seal, approximately 80% of the manholes tested showed no leakage. A further 15% had slow leaks. Only 5% had significant leaks.
Syntheses and Spectroscopic Characterization of Selected Methyl
Quinolinylphosphonic and Quinolinylphosphinic Acids; Rationalized based on DFT
Calculation
Authors: Nycz Jacek E. , Karaush-Karmazin Nataliya , Minaev Boris , Minaeva Valentina , Małecki Jan G. , Książek Maria , Swoboda Daniel , Kusz Joachim 
Published: April 2024

Abstract:
The quinoline derivatives arouse interest due to their broad spectrum of activity.
The phosphorus compounds under investigation, quinolinylphosphonic and -phosphinic
acids and aminophenylphosphonic and -phosphinic acids, possess potent bioactive properties,
mimicking amino acids, phosphate esters, anhydrides, or carboxylate groups in enzymes.
Despite its potential value, there is no reported example of quinolinylphosphonic or -
phosphinic acids with phosphonic or phosphinic functional groups connected directly to the
benzene ring in quinoline constitution. The selected quinoline derivatives have been synthesized
by adopting the Skraup-Doebner-Von Miller reaction. To this end, the syntheses of
aminophenylphosphonic and -phosphinic acids were conducted and afforded the target
products with high yield. All structures have been proven by the combination of NMR, IR,
MS, and HRMS techniques and were rationalized based on DFT calculation. The structures of triphenylphosphane
oxide (TPO), diphenylphosphosphinic acid (1c), (tert-butyl)phenylphosphinic acid (1d) and
bis(3-nitrophenyl)phosphinic acid (2c) were determined by single-crystal X-ray diffraction measurements. The
Hirshfeld surface analyses for 1c, 1d and 2c were performed to analyze the intermolecular interactions in their
crystal structures. According to our findings, the presence of numerous intermolecular PO•••H, NO•••H, and
CH•••O contacts stabilizes the crystal structures. The NO•••H interactions manifest in the IR spectrum of 2c
crystal as a narrow band with a maximum at 3088 cm-1. The PO•••H intermolecular interactions are attributed to
a weak experimental band at 1288 cm-1.
Analysis on the Path to Improve College Students' Innovation Ability
Authors: Guan Lijie 
Published: April 2024

The core elements of innovation or creativity mainly include creative thinking and creative personality. Universities should start from the perspectives of collaborative participation, service and publicity, establish a sound innovation education mechanism, link up professional teaching, develop characteristic entrepreneurship and innovation courses, build diversified entrepreneurship and innovation practice platforms, and hold entrepreneurship and innovation competitions, so as to promote college students to accumulate knowledge, skills and experience in innovation and entrepreneurship in practice.
Tick-borne infections in the Leningrad oblast: incidence and seroprevalence
Authors: Karmokov I. A. , Riabiko E. G. , Baimova R. R. , Buts L. V. , Khalilov E. S. , Grechishkina D. I. , Lyzenko I. S. , Bachinin I. A. , Tokarevich N. K. 
Published: April 2024

The study’s objective was to reveal trends in infections transmitted by ixodes ticks epidemic processes and the level of seroprevalence of the population to the tick-borne encephalitis virus, Borrelia burgdorferi sensu lato, Coxiella burnetii, Anaplasma phagocytophilum and Ehrlichia chaffeensis/ E. muris in the Leningrad Oblast.Materials and methods. A retrospective epidemiological analysis of the tick-bite incidence rate, the ixodic tick-borne borreliosis, tick-borne encephalitis, Q fever, human granulocytic anaplasmosis and human monocytic ehrlichiosis incidence rates, as well as vaccination against tick-borne encephalitis of the population of the Leningrad Oblast in 20112020. The official data of the tick-bite incidence rate, infections transmitted by ixodes ticks incidence rates and vaccination of the population was taken from the forms of federal statistical observation No. 2 and No. 5. Blood was sampled in 2019-2020 from randomly selected donors. Blood serum samples were examined by enzyme-linked immunosorbent assay for the presence of IgG antibodies to the pathogens of the studied infections using commercial test systems according to the manufacturer’s instructions.Results. In the Leningrad Oblast, in 2011-2020, there was a downward trend in the tick-bite incidence rate, as well as in the incidence rates of infections transmitted by ixodic ticks. The long-term average tick bite incidence rate was 369.0. The long-term average incidence rate of ixodic tick–borne borreliosis was 4.1; tick–borne encephalitis was 1.4; Q fever was 0.02. During the analyzed period, no cases of human granulocytic anaplasmosis and human monocytic ehrlichiosis were reported. The seroprevalence to tick-borne encephalitis virus was 1.7%; to B. burgdorferi s. l. – 3.7%; to C. burnetii – 1.8%; to A. phagocytophilum – 1.0%; to E. chaffeensis/ E.muris – 3.2%.Conclusion. The results obtained indicate the existence of active natural foci of infections transmitted by ixodes ticks, fairly frequent contact of the residents with these foci, and possible significant hypodiagnosis of these infections in the Leningrad Oblast.
POLA PEWARISAN TARI COKEK SIPATMO DIKAMPUNG WISATA BUDAYA TEHYAN KOTA TANGERANG
Authors: Toyibah Lala Halalan , Permanasari Alis Triena , Hadiyatno Hadiyatno 
Published: April 2024

Penelitian ini dilatarbelakangi Tarian Cokek Sipatmo yang merupakan hasil dari akulturasi budaya Betawi dan Tionghoa yang didukung oleh pola pewarisan dalam proses perkembanganya. Adapun tujuan penelitian diantaranya adalah untuk menggali informasi mengenai pola pewarisan Tari Cokek Sipatmo dan faktor yang mempengaruhi pola pewarisan Tari Cokek Sipatmo. Metode penelitian yang digunakan yaitu metode kualitatif deskriptif dengan teknik pengumpulan data melalui observasi, wawancara, dan dokumentasi, serta analisis data dilakukan dengan reduksi data, penyajian data, dan menginterpretasikan informasi yang diperoleh. Berdasarkan hasil penelitian didapatkan bahwa Tari Cokek Sipatmo melalui pola pewarisan diagonal dengan melibatkan dukungan pewarisan dari lingkungan sosial di Kampung Wisata Budaya Tehyan dan Lembaga Pendidikan yang diterapkan sebagai materi pada ekstrakulikuler di SMK Kristen Gracia. Adapun faktor yang mempengaruhi pola pewarisan meliputi motivasi prestasi, motivasi afiliasi, motivasi kompetensi, motivasi kekuasaan dan dukungan dari lingkungan sekitar Kampung Wisata Budaya Tehyan, kebijakan pemerintah serta aspek sosial budaya dan ekonomi, sehingga Tari Cokek Sipatmo tetap berkembang sampai saat ini
Kooperatywy mieszkaniowe jako innowacyjne rozwiązanie na polskim rynku nieruchomości
Authors:   Uniwersytet Ekonomiczny w Krakowie, Badura Ewelina 
Published: April 2024

The first works on the act on housing cooperatives appeared in mid-2019. Work on the project of the then Ministry of Investment and Development was interrupted by the election calendar. The second attempt took place in 2020 (draft act of April 9, 2020 on housing cooperatives). The project is part of the concept contained in the National Housing Program. During the consultations, a number of comments and opinions were received. According to, inter alia, The original draft of the Government Legislation Center contained the statutory privilege of cooperatives over other entities operating in the field of housing construction. For this reason, it was necessary to prepare a new draft act on housing cooperatives and the rules for the sale of real estate belonging to the municipal real estate resource in order to support the implementation of housing investments, which appeared on July 21, 2021. on a voluntary association of people who pursue their housing goals. The project relates not only to housing cooperatives, but also to newly established housing cooperatives.