bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effects of Early and Late Nocturnal Sleep on Declarative and Procedural Memory
Authors: Plihal Werner , Born Jan 
Published: February 2008

Abstract
Recall of paired-associate lists (declarative memory) and mirror-tracing skills (procedural memory) was assessed after retention intervals defined over early and late nocturnal sleep. In addition, effects of sleep on recall were compared with those of early and late retention intervals filled with wakefulness. Twenty healthy men served as subjects. Saliva cortisol concentrations were determined before and after the retention intervals to determine pituitary-adrenal secretory activity. Sleep was determined somnopolygraphically. Sleep generally enhanced recall when compared with the effects of corresponding retention intervals of wakefulness. The benefit from sleep on recall depended on the phase of sleep and on the type of memory: Recall of paired-associate lists improved more during early sleep, and recall of mirror-tracing skills improved more during late sleep. The effects may reflect different influences of slow wave sleep (SWS) and rapid eye movement (REM) sleep since time in SWS was 5 times longer during the early than late sleep retention interval, and time in REM sleep was twice as long during late than early sleep (p &lt; 0.005). Changes in cortisol concentrations, which independently of sleep and wakefulness were lower during early retention intervals than late ones, cannot account for the effects of sleep on memory. The experiments for the first time dissociate specific effects of early and late sleep on two principal types of memory, declarative and procedural, in humans.
Parents of Children with Asperger Syndrome: What is the Cognitive Phenotype?
Authors: Baron-Cohen Simon , Hammer Jessica 
Published: February 2008

Abstract
Two cognitive anomalies have been found in autism: a superiority on the Embedded Figures Task and a deficit in “theory of mind.” Using adult-level versions of these tasks, the present study investigated if parents of children with Asperger Syndrome might show a mild variant of these anomalies, as might be predicted from a genetic hypothesis. Significant differences were found on both measures. Parents were significantly faster than controls on the Embedded Figures Task and slightly but significantly less accurate at interpreting photographs of the eye region of the face in terms of mental states. The results are discussed in terms of the broader cognitive phenotype of Asperger Syndrome and in terms of their implications for cognitive neuroscientific theories of the condition.
Face-Specific Processing in the Human Fusiform Gyrus
Authors: McCarthy Gregory , Puce Aina , Gore John C. , Allison Truett 
Published: February 2008

Abstract
The perception of faces is sometimes regarded as a specialized task involving discrete brain regions. In an attempt to identi$ face-specific cortex, we used functional magnetic resonance imaging (fMRI) to measure activation evoked by faces presented in a continuously changing montage of common objects or in a similar montage of nonobjects. Bilateral regions of the posterior fusiform gyrus were activated by faces viewed among nonobjects, but when viewed among objects, faces activated only a focal right fusiform region. To determine whether this focal activation would occur for another category of familiar stimuli, subjects viewed flowers presented among nonobjects and objects. While flowers among nonobjects evoked bilateral fusiform activation, flowers among objects evoked no activation. These results demonstrate that both faces and flowers activate large and partially overlapping regions of inferior extrastriate cortex. A smaller region, located primarily in the right lateral fusiform gyrus, is activated specifically by faces.
How Do Monkeys Look at Faces?
Authors: Nahm Frederick K. D. , Perret Amelie , Amaral David G. , Albright Thomas D. 
Published: February 2008

Abstract
Facial displays are an important form of social communication in nonhuman primates. Clues to the information conveyed by faces are the temporal and spatial characteristics of ocular viewing patterns to facial images. The present study compares viewing patterns of four rhesus monkeys (Macaca mulatta) to a set of 1- and 3-sec video segments of conspecific facial displays, which included open-mouth threat, lip-smack, yawn, fear-grimace, and neutral profile. Both static and dynamic video images were used. Static human faces displaying open-mouth threat, smile, and neutral gestures were also presented. Eye position was recorded with a surgically implanted eye-coil. The relative perceptual salience of the eyes, the midface, and the mouth across different expressive gestures was determined by analyzing the number of eye movements associated with each feature during static and dynamic presentations. The results indicate that motion does not significantly affect the viewing patterns to expressive facial displays, and when given a choice, monkeys spend a relatively large amount of time inspecting the face, especially the eyes, as opposed to areas surrounding the face. The expressive nature of the facial display also affected viewing patterns in that threatening and fear-related displays evoked a pattern of viewing that differed from that recorded during the presentation of submissive-related facial displays. From these results we conclude that (1) the most important determinant of the visual inspection patterns of faces is the constellation of physiognomic features and their configuration, but not facial motion, (2) the eyes are generally the most salient facial feature, and (3) the agonistic or affiliative dimension of an expressive facial display can be delineated on the basis of viewing patterns.
Intact Priming for Novel Perceptual Representations in Amnesia
Authors: Hamann Stephan B. , Squire Larry R. 
Published: February 2008

AbstractRecent studies have challenged the notion that priming for ostensibly novel stimuli such as pseudowords (REAB) reflects the creation of new representations. Priming for such stimuli could instead reflect the activation of familiar memory representations that are orthographically similar (READ) and/or the activation of subparts of stimuli (RE, EX, AR), which are familar because they occur commonly in English. We addressed this issue in three experiments that assessed perceptual identification priming and recognition memory for novel and familiar letter strings in amnesic patients and control subjects. Priming for words, pseudowords, and orthographically illegal nonwords was fully intact in the amnesic patients following a single exposure, whereas recognition memory was impaired for the same items. Thus, priming can occur for stimuli that are unlikely to have preexisting representations. Words and pseudowords exhibited twice as much priming as illegal nonwords, suggesting that activation may contribute to priming for words and wordlike stimuli. Additional results showed that priming for illegal nonwords resulted from the formation of new perceptual associations among the component letters of each nonword rather than the activation of individual letter representations. In summary, the results demonstrate that priming following a single exposure can depend on the creation of new perceptual representations and that such priming is independent of the brain structures essential for declarative memory.
Segregating Semantic from Phonological Processes during Reading
Authors: Price C. J. , Moore C. J. , Humphreys G. W. , Wise R. J. S. 
Published: February 2008

Abstract
A number of previous functional neuroimaging studies have linked activation of the left inferior frontal gyms with semantic processing, yet damage to the frontal lobes does not critically impair semantic knowledge. This study distinguishes between semantic knowledge and the strategic processes required to make verbal decisions. Using positron emission tomography (PET), we identify the neural correlates of semantic knowledge by contrasting semantic decision on visually presented words to phonological decision on the same words. Both tasks involve identical stimuli and a verbal decision on central lingual codes (semantics and phonology), but the explicit task demands directed attention either to meaning or to the segmentation of phonology. Relative to the phonological task, the semantic task was associated with activations in left extrasylvian temporal cortex with the highest activity in the left temporal pole and a posterior region of the left middle temporal cortex (BA 39) close to the angular gyrus. The reverse contrast showed increased activity in both supramarginal gyri, the left precentral sulcus, and the cuneus with a trend toward enhanced activation in the inferior frontal cortex. These results fit well with neuropsychological evidence, associating semantic knowledge with the extrasylvian left temporal cortex and the segmentation of phonology with the perisylvian cortex.
Effects of Memory Load and Distraction on Performance and Event-Related Slow Potentials in a Visuospatial Working Memory Task
Authors: Geffen Gina M. , Wright Margaret J. , Green Heather J. , Gillespie Nicole A. , Smyth David C. , Evans David M. , Geffen Laurence B. 
Published: February 2008

Abstract
Brain electrical activity related to working memory was recorded at 15 scalp electrodes during a visuospatial delayed response task. Participants (N = 18) touched the remembered position of a target on a computer screen after either a 1 or 8 sec delay. These memory trials were compared to sensory trials in which the target remained present throughout the delay and response periods. Distractor stimuli identical to the target were briefly presented during the delay on 30% of trials. Responses were less accurate in memory than sensory trials, especially after the long delay. During the delay slow potentials developed that were significantly more negative in memory than sensory trials. The difference between memory and sensory trials was greater at anterior than posterior electrodes. On trials with distractors, the slow potentials generated by memory trials showed further enhancement of negativity, whereas there were minimal effects on accuracy of performance. The results provide evidence that engagement of visuospatial working memory generates slow wave negativity with a timing and distribution consistent with frontal activation. Enhanced brain activity associated with working memory is required to maintain performance in the presence of distraction.
Word, Pseudoword, and Nonword Processing: A Multitask Comparison Using Event-Related Brain Potentials
Authors: Ziegler Johannes C. , Besson Mireille , Jacobs Arthur M. , Nazir Tatjana A. , Carr Thomas H. 
Published: February 2008

Abstract
Event-related brain potentials (ERPs) to words, pseudowords, and nonwords were recorded in three different tasks. A letter search task was used in Experiment 1. Performance was affected by whether the target letter occurred in a word, a pseudoword, or a random nonword. ERP results corroborated the behavioral results, showing small but reliable ERP differences between the three stimulus types. Words and pseudowords differed from nonwords at posterior sites, whereas words differed from pseudowords and nonwords at anterior sites. Since deciding whether the target letter was present or absent co-occurred with stimulus processing in Experiment 1, a delayed letter search task was used in Experiment 2. ERPs to words and pseudowords were similar and differed from ERPs to nonwords, suggesting a primary role of orthographic and phonological processing in the delayed letter search task. To increase semantic processing, a categorization task was used in Experiment 3. Early differences between ERPs to words and pseudowords at left posterior and anterior locations suggested a rapid activation of lexico-semantic information. These findings suggest that the use of ERPs in a multiple task design makes it possible to track the time course and the activation of multiple sources of linguistic information when processing words, pseudowords, and nonwords. The task-dependent nature of the effects suggests that the language system can use multiple sources of linguistic information in flexible and adaptive ways.
Individual Differences in Inference Generation: An ERP Analysis
Authors: George Marie St. , Mannes Suzanne , Hoffman James E. 
Published: February 2008

Abstract
Readers routinely draw inferences with remarkable efficiency and seemingly little cognitive effort. The present study was designed to explore different types of inferences during the course of reading, and the potential effects of differing levels of working memory capacity on the likelihood that inferences would be made. The electroencephalogram (EEG) was recorded from five scalp sites while participants read 90 paragraphs, composed of 60 experimental paragraphs and 30 filler paragraphs. Each experimental paragraph was four sentences long, and the final sentence stated explicitly the inference that readers did or did not make. There were four types of experimental paragraphs: (1) Bridging inference, (2) Elaborative inference, (3) Word-Based Priming control, and (4) No Inference control. Participants were tested using the Daneman and Carpenter (1980) Reading Span Task and categorized as having low or high working memory capacity. The average peaks of the N400 component of the event-related brain potential (EM) were used as a measure of semantic priming and integration, such that the lower the N400 was in response to the explicitly stated inference concept, the more likely it was that the reader made the inference. Results indicate that readers with high working memory capacity made both bridging (necessary) and elaborative (optional) inferences during reading, whereas readers with low working memory capacity made only bridging inferences during reading. We interpret the findings within the framework of the Capacity Constrained Comprehension model of Just and Carpenter (1992).
Event-Related Brain Potentials Following Incorrect Feedback in a Time-Estimation Task: Evidence for a “Generic” Neural System for Error Detection
Authors: Miltner Wolfgang H. R. , Braun Christoph H. , Coles Michael G. H. 
Published: February 2008

Abstract
We examined scalp-recorded event-related potentials following feedback stimuli in a time-estimation task. Six hundred msec after indicating the end of a 1 sec interval, subjects received a visual, auditory, or somatosensory stimulus that indicated whether the interval they had produced was correct. Following feedback indicating incorrect performance, a negative deflection occurred, whose characteristics corresponded closely to those of the component (the error-related negativity) that accompanies errors in choice reaction time tasks. Furthermore, equivalent dipole analysis suggested that, for all three modalities, the distribution of the scalp potential was consistent with a local source in the anterior cingulate cortex or a more distributed source in the supplementary motor areas. These loci correspond closely to those described previously for the error-related negativity. We conclude that the error-related negativity is the manifestation of the activity of a “generic” neural system involved in error detection.
A Developmental Functional MRI Study of Prefrontal Activation during Performance of a Go-No-Go Task
Authors: Casey B. J. , Trainor Rolf J. , Orendi Jennifer L. , Schubert Anne B. , Nystrom Leigh E. , Giedd Jay N. , Castellanos F. Xavier , Haxby James V. , Noll Douglas C. , Cohen Jonathan D. , Forman Steven D. , Dahl Ronald E. , Rapoport Judith L. 
Published: February 2008

Abstract
This study examines important developmental differences in patterns of activation in the prefrontal cortex during performance of a Go-No-Go paradigm using functional magnetic resonance imaging (fMRI). Eighteen subjects (9 children and 9 adults) were scanned using gradient echo, echo planar imaging during performance of a response inhibition task. The results suggest four general findings. First, the location of activation in the prefrontal cortex was not different between children and adults, which is similar to our earlier pediatric fMRI results of prefrontal activation during a working memory task (Casey et al., 1995). Second, the volume of activation was significantly greater for children relative to adults. These differences in volume of activation were observed predominantly in the dorsal and lateral prefrontal cortices. Third, although inhibitory processes have typically been associated with more ventral or orbital frontal regions, the current study revealed activation that was distributed across both dorsolateral and orbitofrontal cortices. Finally, consistent with animal and human lesion studies, activity in orbital frontal and anterior cingulate cortices correlated with behavioral performance (i.e., number of false alarms). These results further demonstrate the utility of this methodology in studying pediatric populations.
Harmonizing the Resistance, Resisting the Harmony: A Critical Discourse on the Reconstruction of Indigenous Theory of Gender Justice in Hong Kong
Authors: Chiu Man-Chung 
Published: February 2008

AbstractIn Hong Kong, even though the Bill of Rights Ordinance (the localized version of ICCPR), Sex Discrimination Ordinance and a series of legal reforms were enacted and introduced respectively in 1991 and 1994, gender discrimination in legal discourse still persists. Chinese customary law, which only recognises the male's right to build small houses in the New Territories, remains an exception under the Sex Discrimination Ordinance; and the oppression of (female) sex workers is not yet recognized. Some politicians argue that discrimination is inherent in the Han-Chinese culture of harmony, which is impossible to understand from the Euro-American individual-centric perspective of gender equality. They further quote Daoist YIN-YANG cosmology where YANG/Male/Masculinity is supreme; and Confucian Constant Virtues where women are marginalized as examples showing that Han-Chinese culture, where harmony is hegemonized, cannot tolerate or accept gender equality. This paper adopts a critical perspective in examining the above arguments and points out not only that a “pure” version of patriarchal socio-legal culture in the name of harmony hegemony does not exist, but (indigenous) culture should always be meticulously and critically represented in order to reproduce “justice”. I would also argue that it is possible to scrutinize and explore the spaces of resistance within the Hong Kong Han-Chinese socio-legal culture, where foreign theories of gender justice/equality and related legal reforms can be examined.
On the Parameterization of Evaporation of Raindrops as Simulated by a One-Dimensional Rainshaft Model
Authors: Seifert Axel 
Published: February 2008

Abstract
The process of evaporation of raindrops below cloud base is investigated by numerical simulations using a one-dimensional rainshaft model with bin microphysics. The simulations reveal a high variability of the shape of the raindrop size distributions, which has important implications for the efficiency of evaporation below cloud base.
A new parameterization of the shape of the raindrop size distribution as a function of the mean volume diameter is suggested and applied in a two-moment microphysical scheme. In addition, the effect of evaporation on the number concentration of raindrops is parameterized. A comparison of results of the revised two-moment scheme and the bin microphysics rainshaft model shows that the two-moment scheme is able to reproduce the results of the reference model in a wide parameter range.
Modeling Pulse-to-Pulse Coherent Doppler Sonar
Authors: Zedel L. 
Published: February 2008

Abstract
Coherent Doppler sonar provides a powerful tool for probing boundary layer flows under field and laboratory conditions. However, velocity profiling applications of this technique are complicated by characteristic velocity and range ambiguities. Proper implementation for any application requires careful design so that performance can be accurately predicted. In this paper, a computer model capable of simulating coherent Doppler operation is presented. The point scatterer model operates in three dimensions and accommodates bistatic transducer geometries. Excellent agreement is demonstrated between model simulations and laboratory trials. Some simple model applications are presented. The model has been developed for profiling applications but is equally suited to modeling point measurement acoustic Doppler velocimeters.
Clozapine-induced myocarditis after long-term treatment: case presentation and clinical perspectives
Authors: Lang UE , Willbring M. , von Golitschek R. , Schmeisser A. , Matschke K. , Tugtekin S Malte 
Published: February 2008

Clozapine is the drug of choice for treatment-resistant schizophrenia. Prompted by a patient who developed reversible clozapine-induced myocarditis after long-term treatment with clozapine for several years for chronic-resistant schizophrenia, we undertook a review of the relevant literature. Concerning the myocarditis, the patient recovered rapidly by withdrawal of clozapine and with supportive management. Psychiatric stabilisation of the patient was at least possible with a combination of quetiapine (600 mg) and amisulpride (800 mg). Well-designed studies with the aim to specifically investigate treatment options after clozapine are limited and clinical possibilities are discussed in this paper. Olanzapine and combinations using non-clozapine atypical neuroleptics have partly shown improvement, whereas evidence for successful augmentation with mood stabilisers, anticonvulsants or electroconvulsive therapy in treatment-resistant schizophrenia is limited.
Impact of risperidone long acting injection on resource utilization in psychiatric secondary care
Authors: Taylor M. , Currie A. , Lloyd K. , Price M. , Peperell Kate 
Published: February 2008

Risperidone long acting injection (RLAI) is the only long acting atypical antipsychotic available in the UK. Its impact on NHS resource use has not been widely studied. This review of medical records was conducted to quantify the impact of RLAI on NHS psychiatric secondary care resource use, primarily in terms of episodes of inpatient hospital care 12 months before and 12 months after RLAI initiation. Data on number of hospitalizations and hospital bed days were collected retrospectively, from patient notes and hospital databases in four acute psychiatric units in the UK for all individuals with a diagnosis of schizophrenia or schizoaffective disorder who were prescribed RLAI more than 12 months previously. Data were collected on 100 individuals (58 male) with a mean age 40.8 years (range 19—70). The median duration of illness before RLAI initiation was 12 years (range six months to 43 years). There were 62 admissions in the 12 months pre-RLAI, falling to 22 admissions in the 12 months post-RLAI. Number of admissions, we argue, offer a more reliable indicator of the impact of treatment than total hospital bed days in this type of study. In this study there were 40 fewer admissions in the 12 months after RLAI was initiated compared with the previous 12 months. This is important as readmission is a good proxy measure of relapse, and adherence to medication is known to be a key factor in relapse prevention.