bluuebunny/crossref_metadata_2025_split huggingface dataset:
A detachable interface for stable low-voltage stretchable transistor arrays and high-resolution X-ray imaging
Authors: Bian Yangshuang , Zhu Mingliang , Wang Chengyu , Liu Kai , Shi Wenkang , Zhu Zhiheng , Qin Mingcong , Zhang Fan , Zhao Zhiyuan , Wang Hanlin , Liu Yunqi , Guo Yunlong 
Published: March 2024

AbstractChallenges associated with stretchable optoelectronic devices, such as pixel size, power consumption and stability, severely brock their realization in high-resolution digital imaging. Herein, we develop a universal detachable interface technique that allows uniform, damage-free and reproducible integration of micropatterned stretchable electrodes for pixel-dense intrinsically stretchable organic transistor arrays. Benefiting from the ideal heterocontact and short channel length (2 μm) in our transistors, switching current ratio exceeding 106, device density of 41,000 transistors/cm2, operational voltage down to 5 V and excellent stability are simultaneously achieved. The resultant stretchable transistor-based image sensors exhibit ultrasensitive X-ray detection and high-resolution imaging capability. A megapixel image is demonstrated, which is unprecedented for stretchable direct-conversion X-ray detectors. These results forge a bright future for the stretchable photonic integration toward next-generation visualization equipment.
Strategies for high-temperature methyl iodide capture in azolate-based metal-organic frameworks
Authors: Pan Tingting , Yang Kaijie , Dong Xinglong , Zuo Shouwei , Chen Cailing , Li Guanxing , Emwas Abdul-Hamid , Zhang Huabin , Han Yu 
Published: March 2024

AbstractEfficiently capturing radioactive methyl iodide (CH3I), present at low concentrations in the high-temperature off-gas of nuclear facilities, poses a significant challenge. Here we present two strategies for CH3I adsorption at elevated temperatures using a unified azolate-based metal-organic framework, MFU-4l. The primary strategy leverages counter anions in MFU-4l as nucleophiles, engaging in metathesis reactions with CH3I. The results uncover a direct positive correlation between CH3I breakthrough uptakes and the nucleophilicity of the counter anions. Notably, the optimal variant featuring SCN- as the counter anion achieves a CH3I capacity of 0.41 g g−1 at 150 °C under 0.01 bar, surpassing all previously reported adsorbents evaluated under identical conditions. Moreover, this capacity can be easily restored through ion exchange. The secondary strategy incorporates coordinatively unsaturated Cu(I) sites into MFU-4l, enabling non-dissociative chemisorption for CH3I at 150 °C. This modified adsorbent outperforms traditional materials and can be regenerated with polar organic solvents. Beyond achieving a high CH3I adsorption capacity, our study offers profound insights into CH3I capture strategies viable for practically relevant high-temperature scenarios.
Global annual wetland dataset at 30 m with a fine classification system from 2000 to 2022
Authors: Zhang Xiao , Liu Liangyun , Zhao Tingting , Wang Jinqing , Liu Wendi , Chen Xidong 
Published: March 2024

AbstractWetlands play a key role in maintaining ecological balance and climate regulation. However, due to the complex and variable spectral characteristics of wetlands, there are no publicly available global 30-meter time-series wetland dynamic datasets at present. In this study, we present novel global 30 m annual wetland maps (GWL_FCS30D) using time-series Landsat imagery on the Google Earth Engine platform, covering the period of 2000–2022 and containing eight wetland subcategories. Specifically, we make full use of our prior globally distributed wetland training sample pool, and adopt the local adaptive classification and spatiotemporal consistency checking algorithm to generate annual wetland maps. The GWL_FCS30D maps were found to achieve an overall accuracy and Kappa coefficient of 86.95 ± 0.44% and 0.822, respectively, in 2020, and show great temporal variability in the United States and the European Union. We expect the dataset would provide vital support for wetland ecosystems protection and sustainable development.
Modeling liquid rate through wellhead chokes using machine learning techniques
Authors: Dabiri Mohammad-Saber , Hadavimoghaddam Fahimeh , Ashoorian Sefatallah , Schaffie Mahin , Hemmati-Sarapardeh Abdolhossein 
Published: March 2024

AbstractPrecise measurement and prediction of the fluid flow rates in production wells are crucial for anticipating the production volume and hydrocarbon recovery and creating a steady and controllable flow regime in such wells. This study suggests two approaches to predict the flow rate through wellhead chokes. The first is a data-driven approach using different methods, namely: Adaptive boosting support vector regression (Adaboost-SVR), multivariate adaptive regression spline (MARS), radial basis function (RBF), and multilayer perceptron (MLP) with three algorithms: Levenberg–Marquardt (LM), bayesian-regularization (BR), and scaled conjugate gradient (SCG). The second is a developed correlation that depends on wellhead pressure (Pwh), gas-to-liquid ratio (GLR), and choke size (Dc). A dataset of 565 data points is available for model development. The performance of the two suggested approaches is compared with earlier correlations. Results revealed that the proposed models outperform the existing ones, with the Adaboost-SVR model showing the best performance with an average absolute percent relative error (AAPRE) of 5.15% and a correlation coefficient of 0.9784. Additionally, the results indicated that the developed correlation resulted in better predictions compared to the earlier ones. Furthermore, a sensitivity analysis of the input variable was also investigated in this study and revealed that the choke size variable had the most significant effect, while the Pwh and GLR showed a slight effect on the liquid rate. Eventually, the leverage approach showed that only 2.1% of the data points were in the suspicious range.
High biocompatible FITC-conjugated silica nanoparticles for cell labeling in both in vitro and in vivo models
Authors: Nguyen Thi Thuy , Nguyen Hoang Nam , Nghiem Thi Ha Lien , Do Xuan-Hai , To Thanh Thuy , Do Thi Xuan Phuong , Do Dieu Linh , Nguyen Huong Giang , Nguyen Huy Manh , Nguyen Ngoc Dinh , Luu Manh Quynh , Nguyen Trong Nghia , Nguyen Thi Bich Ngoc , Nguyen Van Toan , Pham Van Thanh , Than Uyen Thi Trang , Hoang Thi My Nhung 
Published: March 2024

AbstractFluorescence nanosilica-based cell tracker has been explored and applied in cell biological research. However, the aggregation of these nanoparticles at physiological pH is still the main limitation. In this research, we introduced a novel fluorescence nano-based cell tracker suitable for application in live cells. The silica-coated fluorescein isothiocyanate isomer (FITC-SiO2) nanoparticles (NPs) were modified with carboxymethylsilanetriol disodium salt (FITC-SiO2-COOH), integrating the dianion form of FITC molecules. This nanosystem exhibited superior dispersion in aqueous solutions and effectively mitigated dye leakage. These labeled NPs displayed notable biocompatibility and minimal cytotoxicity in both in vitro and in vivo conditions. Significantly, the NPs did not have negative implications on cell migration or angiogenesis. They successfully penetrated primary fibroblasts, human umbilical vein endothelial cells and HeLa cells in both 2D and 3D cultures, with the fluorescence signal enduring for over 72 h. Furthermore, the NP signals were consistently observed in the developing gastrointestinal tract of live medaka fish larvae for extended periods during phases of subdued digestive activity, without manifesting any apparent acute toxicity. These results underscore the promising utility of FITC-SiO2-COOH NPs as advanced live cell trackers in biological research.
Unbiased serum metabolomic analysis in cats with naturally occurring chronic enteropathies before and after medical intervention
Authors: Questa Maria , Weimer Bart C. , Fiehn Oliver , Chow Betty , Hill Steve L. , Ackermann Mark R. , Lidbury Jonathan A. , Steiner Joerg M. , Suchodolski Jan S. , Marsilio Sina 
Published: March 2024

AbstractChronic enteropathies (CE) are common disorders in cats and the differentiation between the two main underlying diseases, inflammatory bowel disease (IBD) and low-grade intestinal T-cell lymphoma (LGITL), can be challenging. Characterization of the serum metabolome could provide further information on alterations of disease-associated metabolic pathways and may identify diagnostic or therapeutic targets. Unbiased metabolomics analysis of serum from 28 cats with CE (14 cats with IBD, 14 cats with LGITL) and 14 healthy controls identified 1,007 named metabolites, of which 129 were significantly different in cats with CE compared to healthy controls at baseline. Random Forest analysis revealed a predictive accuracy of 90% for differentiating controls from cats with chronic enteropathy. Metabolic pathways found to be significantly altered included phospholipids, amino acids, thiamine, and tryptophan metabolism. Several metabolites were found to be significantly different between cats with IBD versus LGITL, including several sphingolipids, phosphatidylcholine 40:7, uridine, pinitol, 3,4-dihydroxybenzoic acid, and glucuronic acid. However, random forest analysis revealed a poor group predictive accuracy of 60% for the differentiation of IBD from LGITL. Of 129 compounds found to be significantly different between healthy cats and cats with CE at baseline, 58 remained different following treatment.
NADPH oxidase 2 mediates cardiac sympathetic denervation and myocyte autophagy, resulting in cardiac atrophy and dysfunction in doxorubicin-induced cardiomyopathy
Authors: Ma Yuan , Zhao Hui-Ping , Yang Li-Guo , Li Lu , Wang Ai-Lin , Zhang Xiao-Juan , Wang Ke , Yang Bin , Zhu Zong-Feng , Zhang Pei-Jun , Wang Jia-Pu , Chi Rui-Fang , Li Bao , Qin Fu-Zhong , Wang Zhi-Peng 
Published: March 2024

AbstractDoxorubicin has been used extensively as a potent anticancer agent, but its clinical use is limited by its cardiotoxicity. However, the underlying mechanisms remain to be fully elucidated. In this study, we tested whether NADPH oxidase 2 (Nox2) mediates cardiac sympathetic nerve terminal abnormalities and myocyte autophagy, resulting in cardiac atrophy and dysfunction in doxorubicin-induced heart failure. Nox2 knockout (KO) and wild-type (WT) mice were randomly assigned to receive a single injection of doxorubicin (15 mg/kg, i.p.) or saline. WT doxorubicin mice exhibited the decreases in survival rate, left ventricular (LV) wall thickness and LV fractional shortening and the increase in the lung wet-to-dry weight ratio 1 week after the injections. These alterations were attenuated in Nox2 KO doxorubicin mice. In WT doxorubicin mice, myocardial oxidative stress was increased, myocardial noradrenergic nerve fibers were reduced, myocardial expression of PGP9.5, GAP43, tyrosine hydroxylase and norepinephrine transporter was decreased, and these changes were prevented in Nox2 KO doxorubicin mice. Myocyte autophagy was increased and myocyte size was decreased in WT doxorubicin mice, but not in Nox2 KO doxorubicin mice. Nox2 mediates cardiac sympathetic nerve terminal abnormalities and myocyte autophagy—both of which contribute to cardiac atrophy and failure after doxorubicin treatment.
Immunomodulatory potential of Sarcophaga argyostoma larval hemolymph as a natural alternative to berenil in treating Trypanosoma evansi in vivo
Authors: Sadek Al-Shaimaa M. , Farghaly Doaa S. , Kadada Hala , Mashaal Alya 
Published: March 2024

AbstractThis study compared effects of diminazene aceturate (berenil), commonly used to treat domestic animals infected withTrypanosoma evansi,with the hemolymph ofSarcophaga argyostomalarva. The hemolymph may be acting as a possible natural alternative to berenil, based on immunomodulation mediated inflammatory response. Inflammatory mediators and histopathological changes in liver, kidney, and spleen of albino mice experimentally infected withT. evansiwere studied. Mice were divided into five groups: G1, uninfected, untreated (negative control); G2,T. evansiinfected (positive control); G3, infected and treated with berenil; G4, infected and treated with hemolymph; G5, infected and treated with hemolymph 3 days before infection (prophylactic group). Animals in (G4) and (G5) exhibited a significant overall reduction in serum levels of IFN-γ. However, the reduction in TNF-α and IL-6 levels was more limited compared to (G2) and (G3). Notably, an elevation in IL-10 levels was observed compared to animals in other groups. Furthermore, the groups treated with hemolymph demonstrated an alleviation ofT. evansiinfection in contrast to the other groups. This study highlights that the administration ofSarcophaga argyostomalarval hemolymph at a dosage of 0.5 ml/kg significantly inhibitedT. evansiorganisms in vivo, showcasing a pronounced trypanocidal effect.
Enhancement of magnetization and optical properties of CuFe2O4/ZnFe2O4 core/shell nanostructure
Authors: Faramawy A. M. , El-Sayed H. M. 
Published: March 2024

AbstractIn this work, core/shell of CuFe2O4/ZnFe2O4 nanostructure composite was prepared by hydrothermal method. X-ray diffraction (XRD) analysis, transmission electron microscope imaging, energy dispersive X-ray (EDX), and Fourier transform infrared techniques were used to prove the phase formation, morphology, elemental analysis, and cation distribution of core/shell structure, respectively. Furthermore, measurement of the optical properties proved the decrease of photoluminescence (PL) efficiency. The magnetic measurements showed an enhancement of the magnetization by about 63% relative to pure Cu ferrite, and the magnetization curve exhibited superparamagnetic behavior. These results were explained in terms of the depression of the magnetic dead layer thickness in the core/shell structure. The results unleash the promising applications of the prepared samples as transformer cores in the high frequency range and as a photocatalytic agent for water purification and hydrogen production.
Assessing the spatial occupation and ecological impact of human activities in Chengguan district, Lhasa city, Tibetan Plateau
Authors: Xu Lin , Xu Yong , Duan Jian , Wang Yingying , Yang Hua 
Published: March 2024

AbstractIn this study, the ecological impact of human activities and the space occupied by construction and arable land on the Tibetan Plateau were examined, focusing on changes in the net primary productivity (NPP) as a key indicator of ecological health. With the utilization of land use data and multiyear average NPP data from 2002 to 2020, we analyzed the effects of the conversion of zonal vegetation into construction and arable land on carbon sequestration and oxygen release in Chengguan District, Lhasa city. Our findings indicated a marked spatial difference in the NPP among different land types. Regarding the original zonal vegetation, the NPP ranged from 0.2 to 0.3 kg/m2. Construction land showed a decrease in the NPP, with values ranging from 0.16 to 0.26 kg/m2, suggesting a decrease in ecological productivity. Conversely, arable land exhibited an increase in the NPP, with average values exceeding 0.3 kg/m2. This increase suggested enhanced productivity, particularly in regions where the original zonal vegetation provided lower NPP values. However, this enhanced productivity may not necessarily indicate a positive ecological change. In fact, such increases could potentially disrupt the natural balance of ecosystems, leading to unforeseen ecological consequences. The original zonal vegetation, with NPP values ranging from 0.12 to 0.43 kg/m2, exhibited higher ecological stability and adaptability than the other land types. This wider NPP range emphasizes the inherent resilience of native vegetation, which could sustain diverse ecological functions under varying environmental conditions. These findings demonstrate the urgent need for sustainable land use management on the Tibetan Plateau. This study highlights the importance of considering the ecological impact of land use changes in regional development strategies, ensuring the preservation and enhancement in the unique and fragile plateau ecosystem.
Preparation of high-resolution micro/nano dot array by electrohydrodynamic jet printing with enhanced uniformity
Authors: Jin Yiwei , Zhao Ziwei , Chen Jiankui , Chen Wei , Wang Guozhen , Yin Zhouping 
Published: March 2024

AbstractThe high-resolution array is the basic structure of most kinds of microelectronics. Electrohydrodynamic jet (E-Jet) printing technology is widely applied in manufacturing array structures with high resolution, high material compatibility and multi-modal printing. It is still challenging to acquire high uniformity of printed array with micro-nanometer resolution, which greatly influences the performance and lifetime of the microelectronics. In this paper, to improve the uniformity of the printed array, the influence of each parameter on the uniformity of the E-jet printed dot array is studied on the cobuilt NEJ-E/P200 experimental platform, finding the applied voltage plays the most important role in maintaining the uniformity of the printed array. By appropriately adjusting the printing parameters, the dot arrays with different resolutions from 500 pixels per inch (PPI) to 17,000 PPI are successfully printed. For arrays below and over 10,000 PPI, the deviations of the uniformity are within 5% and 10% respectively. In this work, the dot array over 15,000 PPI is first implemented using E-jet printing. The conclusions acquired by experimental analysis of dot array printing process are of great importance in high resolution array printing as it provides practical guidance for parameters adjustment.
Sex drives colonic mucin sialylation in wild mice
Authors: Bennett Alexander R. , Mair Iris , Muir Andrew , Smith Hannah , Logunova Larisa , Wolfenden Andrew , Fenn Jonathan , Lowe Ann E. , Bradley Janette E. , Else Kathryn J. , Thornton David J. 
Published: March 2024

AbstractMucin protein glycosylation is important in determining biological properties of mucus gels, which form protective barriers at mucosal surfaces of the body such as the intestine. Ecological factors including: age, sex, and diet can change mucus barrier properties by modulating mucin glycosylation. However, as our understanding stems from controlled laboratory studies in house mice, the combined influence of ecological factors on mucin glycosylation in real-world contexts remains limited. In this study, we used histological staining with ‘Alcian Blue, Periodic Acid, Schiff’s’ and ‘High-Iron diamine’ to assess the acidic nature of mucins stored within goblet cells of the intestine, in a wild mouse population (Mus musculus). Using statistical models, we identified sex as among the most influential ecological factors determining the acidity of intestinal mucin glycans in wild mice. Our data from wild mice and experiments using laboratory mice suggest estrogen signalling associates with an increase in the relative abundance of sialylated mucins. Thus, estrogen signalling may underpin sex differences observed in the colonic mucus of wild and laboratory mice. These findings highlight the significant influence of ecological parameters on mucosal barrier sites and the complementary role of wild populations in augmenting standard laboratory studies in the advancement of mucus biology.
In vitro hemodynamic performance of a blood pump for self-powered venous assist in univentricular hearts
Authors: Rasooli Reza , Holmstrom Henrik , Giljarhus Knut Erik Teigen , Jolma Ingunn Westvik , Vinningland Jan Ludvig , de Lange Charlotte , Brun Henrik , Hiorth Aksel 
Published: March 2024

AbstractUniventricular heart anomalies represent a group of severe congenital heart defects necessitating early surgical intervention in infancy. The Fontan procedure, the final stage of single-ventricle palliation, establishes a serial connection between systemic and pulmonary circulation by channeling venous return to the lungs. The absence of the subpulmonary ventricle in this peculiar circulation progressively eventuates in failure, primarily due to chronic elevation in inferior vena cava (IVC) pressure. This study experimentally validates the effectiveness of an intracorporeally-powered venous ejector pump (VEP) in reducing IVC pressure in Fontan patients. The VEP exploits a fraction of aortic flow to create a jet-venturi effect for the IVC, negating the external power requirement and driveline infections. An invitro Fontan mock-up circulation loop is developed and the impact of VEP design parameters and physiological conditions is assessed using both idealized and patient-specific total cavopulmonary connection (TCPC) phantoms. The VEP performance in reducing IVC pressure exhibited an inverse relationship with the cardiac output and extra-cardiac conduit (ECC) size and a proportional relationship with the transpulmonary pressure gradient (TPG) and mean arterial pressure (MAP). The ideal VEP with fail-safe features provided an IVC pressure drop of 1.82 ± 0.49, 2.45 ± 0.54, and 3.12 ± 0.43 mm Hg for TPG values of 6, 8, and 10 mm Hg, respectively, averaged over all ECC sizes and cardiac outputs. Furthermore, the arterial oxygen saturation was consistently maintained above 85% during full-assist mode. These results emphasize the potential utility of the VEP to mitigate elevated venous pressure in Fontan patients.
On topological analysis of two-dimensional covalent organic frameworks via M-polynomial
Authors: Yang Hong , Hanif Muhammad Farhan , Siddiqui Muhammad Kamran , Hussain Mazhar , Hussain Nazir , Fufa Samuel Asefa 
Published: March 2024

AbstractCovalent organic frameworks (ZnP-COFs) made of zinc-porphyrin have become effective materials with a variety of uses, including gas storage and catalysis. To simulate the structural and electrical features of ZnP-COFs, this study goes into the computation of polynomials utilizing degree-based indices. We gave a methodical study of these polynomial computations using Excel, illustrating the complex interrelationships between the various indices. Degree-based indices provide valuable insights into the connectivity of vertices within a network. M-polynomials, on the other hand, offer a mathematical framework for representing and studying the properties of 2D COFs. By encoding structural information into a polynomial form, M-polynomials facilitate the calculation of various topological indices, including the Wiener index, Zagreb indices, and more. The different behavior of ZnP-COFs based on degree-based indices was illustrated graphically, and this comparison provided insightful information for prospective applications and the construction of innovative ZnP-COF structures. Moreover, we discuss the relevance of these techniques in the broader context of materials science and the design of functional covalent organic frameworks.