bluuebunny/crossref_metadata_2025_split huggingface dataset:
First Example of Cu(OTf)2-catalyzed Synthesis of Quinoxalines from α-Diazoketones and Aryl 1,2-Diamines
Authors: Yadav J S , Subba Reddy B V , Gopala Rao Y , Narsaiah A V 
Published: February 2008

Abstract
α-Diazoketones undergo smooth coupling with aryl 1,2-diamines in the presence of 10 mol % of copper(II) triflate to provide the corresponding 2-alkyl- or 2-aryl-quinoxalines in excellent yields with high selectivity. Rh2(OAc)4 is also found to be an equally effective catalyst for this transformation. It is a new and alternative approach for the preparation of biologically well-defined quinoxaline derivatives.
Naphthyridine-tethered Oligodeoxyribonucleotides: Dye/DNA Conjugates for Homogeneous SNPs Assays
Authors: Kobori Akio , Mori Takashi , Ubayashi Makoto , Murakami Akira 
Published: February 2008

Abstract
We here report the synthesis and fluorescence properties of naphthyridine-tethered oligodeoxyribonucleotides for discrimination of cytosine-related single nucleotide alterations in DNA. A/C alleles of cytochrome P450 variants (CYP2C19) were successfully discriminated simply by adding baeDANP-ODN under slightly basic conditions.
Unexpected Phase Behaviors of Poly(fumarate)s Carrying Tolane-based Mesogenic Side Chains
Authors: Michinobu Tsuyoshi , Noguchi Hiroshi , Fujii Nozomu , Tokita Masatoshi , Watanabe Junji , Shigehara Kiyotaka 
Published: February 2008

Abstract
Poly(fumarate)s carrying tolane-based mesogenic side chains were for the first time prepared by radical polymerization. The phase behaviors characterized by differential scanning calorimetry (DSC), polarized optical microscopy (POM), and X-ray diffraction (XRD) analysis indicated that the liquid crystalline temperature ranges clearly decreased upon polymerization. This very rare behavior could be derived from the delicate balance between the mesogen structure and the rigid polyfumarate backbone.
A review of ICT systems for HIV/AIDS and anti-retroviral treatment management in South Africa
Authors: Sørensen Tove , Rivett Ulrike , Fortuin Jill 
Published: February 2008

Summary Telemedicine and e-health systems have been proposed as a support tool, to monitor and evaluate HIV/AIDS management strategies. The aim of the present study was to provide an overview of telemedicine and e-health systems for HIV/AIDS in South Africa as a basis for developing an e-health toolkit for anti-retroviral treatment (ART). An initial literature review and a subsequent interactive networking approach were chosen to identify telemedicine and e-health systems, projects and services for HIV/AIDS and ART facilities in low-resource settings and under-served areas. The literature review produced little useful information. In contrast, the face-to-face interviews and the focus group discussions provided useful information about projects and systems which had not been published. The meetings involved 1–5 people per session, about 30 people in total. The review showed that there were some plans for telemedicine and e-health implementation in South Africa. However, there was no all-inclusive ICT-based system in place for AIDS treatment there. With the exception of the major health information systems and electronic patient record systems, none of the telemedicine and e-health systems identified in the review were ready to be deployed across the country as a whole.
The TeleGuard trial of additional telemedicine care in CAD patients. 2 Morbidity and mortality after 12 months
Authors: Waldmann Annika , Katalinic Alexander , Schwaab Bernhard , Richardt Gert , Sheikhzadeh Abdolhamid , Raspe Heiner 
Published: February 2008

Summary In the TeleGuard trial, 1500 patients with established coronary artery disease (CAD) were recruited and randomized to control or intervention groups. Patients in the intervention group were equipped with a 12-lead event recorder and could contact a call centre and transmit an ECG whenever they wished. In a 12-month study, the composite endpoint (all-cause mortality, myocardial infarction, re-hospitalization or re-vascularization) was seen in 40% of the intervention patients and in 38% of the control patients. In both groups, approximately 40% were re-hospitalized. In total, 73 patients experienced re-vascularization, 75 showed an infarction and 33 died. Equipping CAD patients with a 12-lead ECG device and providing a telemedicine centre with 24-hour availability did not decrease risk for the composite endpoint (re-hospitalization, re-vascularization, (subsequent) myocardial infarction and/or death). It is likely that the clinical pathway used in the telemedicine centre led to an increased hospital admission rate in the intervention group.
Automated telephone reminder messages can assist electronic diabetes care
Authors: Mollon Brent , Holbrook Anne M , Keshavjee Karim , Troyan Sue , Gaebel Kathryn , Thabane Lehana , Perera Gihan 
Published: February 2008

Summary Telephone reminder systems have been used to assist in the treatment of many chronic diseases. However, it is unclear if these systems can increase medication and appointment adherence in patients with diabetes without direct patient–provider telephone contact. We tested the feasibility of using an automated telephone reminder system (ATRS) to deliver reminder messages to 253 adults with diabetes enrolled in a randomized controlled trial. Eighty-four percent of the patients were able to register using voice recognition and at least one reminder was delivered to 95% of registered patients over a period of 7.5 months. None of the demographic features studied predicted a patient's ability to enrol or to receive reminder calls. At the end of the study, 63% of patients indicated that they wished to continue to receive ATRS calls. The level of system use as determined by the number of received reminder calls was not associated with a change in the number of physician visits or diabetes-related laboratory tests during follow-up. The clinical benefits and sustainability of ATRS remain unproven, but our results indicate that an automated reminder system can be effective for providing messages to a large group of older patients with diabetes.
Sei epistole mutuae inedite di Procopio di Gaza ed il retore Megezio
Authors: Amato Eugenio 
Published: February 2008

Abstract
L'attento esame della tradizione manoscritta delle epistole di Procopio di Gaza ha permesso al suo ultimo editore (A. Garzya) di pubblicare un corpus di 166 lettere, basato su una recensio molto più ampia rispetto a quella dei suoi predecessori e soprattutto più completo per le nuove lettere, venute alla luce nel corso dei secoli.
Una lettura del θρηνοσ εισ τα παθη και την σταυρωσιν του κυριου και θεου και σωτηροσ ημων Ιησου Χριστου del Cretese Marinos Falieros
Authors: Carpinato Caterina 
Published: February 2008

Abstract
Wim Bakker e Arnold van Gemert hanno recentemente licenziato per la stampa l'edizione critica del Θϱηνος εἰς τὰ Πάθη ϰαὶ τὴν Σταύϱωσιν του Кυϱίου ϰαὶ Θεου ϰαὶ Σωτηϱος ἡμων Ἰησου Хϱιστου, poema drammatico unico nel suo genere, in versi decapentasillabi (in gran parte rimati). L'opera è anche l'unica, tra quelle composte dal poeta cretese Marinos Falieros (1395?–1474) e pervenute fino a noi (complessivamente cinque), ad aver avuto l'onore di esser sottoposta ai torchi dei tipografi veneziani nel Cinquecento. Almeno fino ad oggi non è stato reperito in nessuna biblioteca alcun esemplare di questa cinquecentina. Si è salvato solo un apografo, Tubing. Mb 27, f. 171–184, datato 22 gennaio 1585 e copiato per Martinus Crusius dall'allievo Daniel Schuhmaier. Il componimento di Falieros è arrivato quindi fino a noi solo per un caso fortunato, tramite una sola fonte indiretta, una copia manoscritta di un'unica edizione a stampa (1543/44).
John Lydus and the eastern Praetorian prefecture in the Sixth Century AD
Authors: Kelly Christopher 
Published: February 2008

Abstract

§ 1 On the Magistracies of the Roman State

Sometime in the mid sixth century, John Lydus (“the Lydian”), then a professor of Latin at the State University of Constantinople, decided to write his autobiography. John had led an eventful life (at least in his own re-telling). He was born around 490 in Philadelphia, the chief city of the province of Lydia on the western coast of Asia Minor. In 511, after an expensive education, which included learning Latin, he left his home town for the imperial capital. Arriving in Constantinople, John had high hopes of a successful career. He aimed to secure a post in one of the imperial secretariats (sacra scrinia) whose highly privileged staff, working within the palace, dealt with administrative and judicial matters directly involving the emperor himself (3.26).
Synagoge. Συναγωγὴ λέξεων χϱησίμων. Edited by Ian C. CUNNINGHAM. Sammlung griechischer und lateinischer Grammatiker (SGLG), 10
Authors: Thiel Helmut van 
Published: February 2008

Abstract
Die Synagoge ist das dritte der fünf großen byzantinischen Lexika: Kyrill, Hesych, Synagoge, Photios, Suda. Im Kyrill-Lexikon war erstmals der Wortschatz der heidnischen, hellenistischjüdischen und frühen christlichen griechischen Literatur gesammelt. Es ist in Hesych nachträglich eingearbeitet; etwa ein Drittel des „Hesych“ stammt aus „Kyrill“. Kyrill ist in der Synagoge exzerpiert; etwa 80 Prozent ihrer Glossen lassen sich auf ihn zurückführen, und sie kann durchaus als Kyrill-Rezension angesehen werden, wie es in einer ihrer Handschriften geschieht (vgl. p. 19, 49). Die Synagoge ist nahezu vollständig in Photios und Suda eingearbeitet, und zwar nach der zweiten ihrer beiden überlieferten Rezensionen.
Stylianos LAMPAKES, Γεώϱγιος Παχυμέϱης, πϱωτέϰδιϰος ϰαὶ διϰαιοφύλαξ. Εἰσαγωγιϰό δοϰίμιο. Μονογϱαφίες, 5. Αθήνα, Εθνιϰό Ίδϱυμα Εϱευνών, Ινστιτούτο Βυζαντινών Εϱευνών 2004
Authors: Polemis Ioannis D. 
Published: February 2008

Abstract
According to LAMPAKIS (L.), the main purpose of this book is to offer a detailed biography of Georgios Pachymeres as well as an assessment of his works (p. 9). Unfortunately, it falls far short of achieving either of these objectives. First, the choice of wording – “Introductory essay” – in the title is somewhat infelicitous. The meaning of “essay” in modern Greek is vague, to say the least, and few would apply this term to a book which, in essence, is an unnecessarily long compilation of the known facts about Pachymeres' life and works. Only an attempt by the author to interpret the thought of Pachymeres or to place his work in the broader historical context of his times would have convincingly justified the term “essay” for this particular monograph.
Anastasia OIKONOMOU-LANIADO, Argos Paléochrétienne : Contribution à l'étude du Péloponnèse Byzantin. BAR International Series, 1173
Authors: Petridis Platon 
Published: February 2008

Abstract
Ce livre constitue une étude de la topographie de la ville d'Argos à l'époque protobyzantine (IVe–VIIe siècles). Il s'agit en effet d'une mise au point de l'état des recherches archéologiques, essentiellement des fouilles de sauvetage, menées par le Service Archéologique grec dont l'auteur fut épimélète responsable du département d'Argos pendant de longues années et jusqu'à sa mort précoce en 1998.
Filippo RONCONI, La traslitterazione dei testi greci. Quaderni della Rivista di Bizantinistica, 7
Authors: Schreiner Peter 
Published: February 2008

Abstract
Zu den kulturgeschichtlich interessantesten und textgeschichtlich gefährlichsten gehören Veränderungen im System des Datenträgers, um einen ganz modernen Ausdruck zu verwenden. Die Geschichte der europäischen Literatur hat mehrere Perioden aufzuweisen, in denen sich grundlegende Änderungen dieser Art vollziehen: der Übergang von der Rolle zum Buch-Codex im 4. Jahrhundert, bei der sich der materielle Träger, aber nicht (unmittelbar) die Schriftform ändert, die Umschrift von der Majuskel in die Minuskel (bei unterschiedlichen Ausgangspunkten in Byzanz und im Westen im 9. und den folgenden Jahrhunderten), wobei der Codex als Träger unverändert blieb, die Einführung des Buchdrucks und schließlich die elektronische Speicherung von Texten und ihre beliebige Weiterverarbeitung, deren Bedeutung und Folgen erst spätere Generationen beurteilen und einschätzen können.
Christine STRUBE, Baudekoration im Nordsyrischen Kalksteinmassiv. Bd. II: Das 6. und frühe 7. Jahrhundert. Damaszener Forschungen, 11
Authors: Arbeiter Achim 
Published: February 2008

Abstract
Kaum ein Arbeitsgebiet der frühchristlichen und der byzantinischen Kunstgeschichte hat in moderner Zeit an einer so großen Differenz zwischen Erkenntnispotential und tatsächlicher Erkundung gekrankt wie die Denkmälerlandschaft im Nordsyrischen Kalksteinmassiv: Die dort erhaltenen spätantiken Siedlungen und Sakralbauten sind in ihrer instruktiven Präsenz einzigartig und müßten demnach von ganzen Heerscharen engagierter Feldforscher studiert werden, doch sind es in Wirklichkeit unsäglich wenige, die sich jenen Denkmälern zuwenden. Wer das sehr überschaubare Schrifttum, beginnend mit Melchior DE VOGÜÉ (1865/77) über die amerikanischen Expeditionsergebnisse des angebrochenen 20. Jh.s bis hin zur Gegenwart studiert und auch selbst jene Stätten aufsucht, dem wird obendrein rasch klar, wie erbarmungslos die Zerstörung der für die ganze Menschheit unersetzlichen Monumente fortgeschritten ist und fortschreitet. Um ein Vielfaches müßten die Schutzmaßnahmen und die wissenschaftlichen Aktivitäten an diesem einzigartigen Erbe gesteigert werden. Vorbildlich sind da die Bemühungen von Christine Strube (S.), deren neuestes einschlägiges Buch hier zu kommentieren ist.
Measurement of Normal Pressures and Friction Forces Acting on Buried Pipes Subjected to Cyclic Axial Displacements in Laboratory Experiments
Authors: Weidlich I. , Achmus M. 
Published: February 2008

Abstract
The earth pressure acting on buried pipes is decisive for the pipe design. For pipes shifting in the ground, such as district heating pipes, which are subjected to cyclic temperature loading, the mobilizable friction force, which is also dependent on the earth pressure load, is a very important quantity. Friction force changes with cyclic axial displacement of a pipeline in operation. A special testing device was designed to investigate the friction forces and the normal pressures on a pipe buried in sand and how these change during cyclic axial displacement dependent on system and soil parameters. The experimental setup is presented, and in particular the application of the tactile pressure sensor, the special measuring technique used, is described. The dependence of the decrease in friction force on pipe diameter, soil overburden height, and relative density of the soil was investigated in the tests. The results are presented and the findings are discussed.
Long-term effects of Helicobacter pylori eradication on circulating ghrelin and leptin concentrations and body composition in prepubertal children
Authors: Pacifico Lucia , Anania Caterina , Osborn John F , Ferrara Eva , Schiavo Elisa , Bonamico Margherita , Chiesa Claudio 
Published: February 2008

BackgroundHelicobacter pylori, and the chronic gastric inflammation that it causes, may compromise the function and survival of ghrelin-producing cells, resulting in a decrease of circulating ghrelin levels. This finding raises the possibility that the infection might affect growth in children by reducing the ghrelin production.AimsTo determine baseline circulating levels of ghrelin and leptin in prepubertal children with and without H. pylori infection and to evaluate the long-term effects of H. pylori eradication on circulating levels of ghrelin and leptin as well as on body composition.PatientsThirty children with H. pylori-associated gastritis, 35 children with H. pylori-negative gastric mucosa, and 20 healthy controls were studied.ResultsAt baseline, while leptin levels were significantly lower in H. pylori-positive patients, ghrelin concentrations did not differ among the three study groups. However, a significant inverse correlation between ghrelin concentrations and histological severity of gastritis was found. Eradication of the organism was associated with a progressive decrease in ghrelin concentrations over baseline at both 6- and 12-month follow-ups. SDS-body mass index (BMI), lean and fat mass, as well as leptin concentrations, significantly increased over baseline at both follow-ups.ConclusionsIn prepubertal children, serum ghrelin concentrations are inversely related to the severity of H. pylori-associated gastritis. In these youngsters, long-term eradication of H. pylori infection is associated with a significant increase in BMI, lean and fat mass along with a significant decrease in circulating ghrelin levels and an increase in leptin levels.
Combined immunostaining with galectin-3, fibronectin-1, CITED-1, Hector Battifora mesothelial-1, cytokeratin-19, peroxisome proliferator-activated receptor-γ, and sodium/iodide symporter antibodies for the differential diagnosis of non-medullary thyroid carcinoma
Authors: Liu Ying Y , Morreau Hans , Kievit Job , Romijn Johannes A , Carrasco Nancy , Smit Johannes W 
Published: February 2008

ObjectivesThe microscopic distinction between benign and malignant thyroid lesions in clinical practice is still largely based on conventional histology. This study was performed to evaluate the diagnostic value of galectin-3 (Gal-3), Hector Battifora mesothelial-1 (HBME-1), cytokeratin (CK)-19, CBP P300-interacting transactivator with glutamic acid E- and aspartic acid D-rich C-terminal domain (CITED-1), fibronectin (FN)-1, peroxisome proliferator-activated receptor (PPAR)-γ, and intracellular sodium/iodide symporter (iNIS) immunostaining in a large panel of thyroid neoplasms. Our study differed from earlier ones with regard to the identification of optimal semiquantitative cut-off levels using receiver operator curve (ROC) analysis and hierarchical cluster analysis.MethodsWe used tissue arrays containing 177 thyroid tissues: 100 benign tissues (including normal thyroid, Graves disease, multinodular goiter, and follicular adenoma (FA)) and 77 thyroid carcinomas (including papillary thyroid carcinoma (PTC), follicular thyroid carcinoma, and follicular variant of PTC (FVPTC)). Antibody staining was scored semiquantitatively based on the ROC analyses and with hierarchical cluster analysis.ResultsIn general, we found overexpression of FN-1, CITED-1, Gal-3, CK-19, HBME-1, and iNIS in malignant thyroid lesions. Gal-3, FN-1, and iNIS had the highest accuracy in the differential diagnosis of follicular lesions. A panel of Gal-3, FN-1, and iNIS, identified by hierarchical cluster analysis, had a 98% accuracy to differentiate between FA and malignant thyroid lesions. In addition, HBME-1 was found to be useful in the differentiation between FA and FVPTC (accuracy 88%).ConclusionWe conclude that identifying optimal antibody panels with cluster analysis increases the diagnostic value in the differential diagnosis of thyroid neoplasms, the combination of FN-1, Gal-3, and iNIS having the best accuracy (98%).
Growth modelling of non-functioning pituitary adenomas in patients referred for surgery
Authors: Honegger Juergen , Zimmermann Sanna , Psaras Tsambika , Petrick Manfred , Mittelbronn Michel , Ernemann Ulrike , Reincke Martin , Dietz Klaus 
Published: February 2008

ObjectiveRecent observational studies have established progression and recurrence rates of pituitary adenomas. However, it is still unknown how individual pituitary adenomas grow over years and whether growth kinetics follow a distinct growth model. The objective of this study was to define a growth model for non-functioning pituitary adenomas.MethodsFifteen patients who had five or more serial high-quality examinations with magnetic resonance images or computerized tomography scans were identified among 216 patients with non-functioning pituitary adenomas. Tumour volumes were assessed using a stereological method based on the Cavalieri principle. Tumour growth during the observation period was analysed and different growth models were fitted to the data.ResultsFifteen pituitary adenomas (12 recurrent tumours and 3 newly diagnosed tumours) were longitudinally observed during a median observation period of 7.4 years (range: 2.3–11.9 years). Growth kinetics could be described either by an exponential growth model (nine patients) or by a logistic model (five patients) with initial exponential growth followed by deceleration of growth. One tumour remained unchanged in size during the observation period. None of the adenomas showed accelerated growth during the observation period. Overall, the linear growth model was not suitable to describe the growth kinetics of non-functioning pituitary adenomas.ConclusionsOur study shows that growth of pituitary adenomas can be described by distinct growth models. Knowledge of growth dynamics has implications for clinical practice and helps to adjust scanning protocols for follow-up investigations.
Hypoactive sexual desire in transsexual women: prevalence and association with testosterone levels
Authors: Elaut Els , De Cuypere Griet , De Sutter Petra , Gijs Luk , Van Trotsenburg Michael , Heylens Gunter , Kaufman Jean-Marc , Rubens Robert , T'Sjoen Guy 
Published: February 2008

ObjectiveAn unknown proportion of transsexual women (defined as post-operative male-to-female transsexuals on oestrogen replacement) experience hypoactive sexual desire disorder (HSDD). It has been suggested that the absence of ovarian androgen production together with oestrogen treatment-related increase in sex hormone-binding globulin (SHBG) levels could be leading to HSDD, due to low levels of biologically available testosterone. This study wishes to document the HSDD prevalence among transsexual women and the possible association to androgen levels.DesignCross-sectional study.MethodsTranssexual women (n=62) and a control group of ovulating women (n=30) participated in this study. Questionnaires measuring sexual desire (sexual desire inventory) and relationship and sexual satisfaction (Maudsley Marital Questionnaire) were completed. Serum levels of total testosterone, LH and SHBG were measured in blood samples obtained at random in transsexual women and in the early follicular phase in ovulating women.ResultsThe transsexual group had lower levels of total and calculated free testosterone (both P<0.001) than the ovulating women. HSDD was reported in 34% of the transsexual and 23% of the ovulating women (P=0.30). Both groups reported similar levels of sexual desire (P=0.97). For transsexual women, no significant correlation was found between sexual desire and total (P=0.64) or free testosterone (P=0.82). In ovulating women, these correlations were significant (P=0.006, resp. P=0.003).ConclusionsHSDD is reported in one-third of transsexual women. This prevalence is not substantially different from controls, despite markedly lower (free) testosterone levels, which argues against a major role of testosterone in this specific group.