bluuebunny/crossref_metadata_2025_split huggingface dataset:
RBF Network Dynamic Sliding Mode Robust Control for Overhead Cranes with Uncertain Parameters
Authors: li shihua , Gao YouShan , Lv Shi-Ning , Wang Ai-Hong , Wan Yu-Fan 
Published: March 2024

Abstract

For the load swing and trolley tracking and positioning issues of overhead crane system during lifting operations with uncertain inherent parameters and partial unknown parameters, a dynamic sliding mode robust control algorithm based on RBF neural network is suggested. The Lyapunov stability of the closed loop error is Theoretically testified by the control algorithm .The control algorithm takes the sliding mode control idea as its structural framework. The design of the sliding mode surface takes into account the impact of the alteration in the control output, makes the sliding mode switching term adaptive by setting fuzzy rules ,and further derives the self adaption laws of the RBF neural networks to adapt the intricated as well as unknown dynamic parts in the system of overhead crane, rendering the operation of the system of overhead crane with no need for any system parameters as the signal input. For the sake of testifying the superior control accuracy under the influence of this tactics, a comparison was made with the layered sliding mode control method, with results demonstrated that the output power of the controller based on above algorithm designed in this paper proves more stable, and there is no long-term high-frequency jitter, while its anti-swing control effect on the load is also standing a better robust performance of any other controllers. It is also exceedingly significant to point out that when the system parameters change to some extent. While the trolley based on this control system can also achieve stable tracking and positioning under zero overshoot.
Cataract Risk Factors Prediction Using Deep Leaning Models
Authors: Saju Binju , R Rajesh 
Published: March 2024

Abstract

Cataracts are diseases that occur due to the existence of protein in the lens that develops an abnormal clumsy region in the eye. This can be avoided when it is recognized and identified in the beginning stages. Recently, data mining techniques have been utilized in classifying the stages of cataracts. This work proposes the risk factors for cataracts and classifies the cataract risk using deep learning models. The data was collected from patients who were diagnosed with cataracts. The proposed method is divided into two stages: pre-processing and classification. Hence, in the initial stage, the dataset is pre-processed by missing values, and the string values are converted into numeric values. Then, for risk prediction, a fuzzy rule-based clinical system is described. This is carried out by collecting information, accessing the risk factors, & creating knowledge from the patient’s clinical info. Then, in the second phase, there is classification-based stage advancement. The Fuzzified output is given to the classifier for classifying the stage advancement. The classifiers like ICNN (Improved Convolutional neural network + Arithmetic Optimization Algorithm), CNN (Convolutional neural network), DNN (Deep neural network), DBN (Deep Belief Network), RNN (Recurrent Neural Network), and GAN (Generative Adversarial Network) are used to classify the classes as Stage advancements category 1 (very fast stage advancement), category 2 (Moderate stage advancement), and category 3 (slow stage advancement-No Change in stage) are determined. The overall implementation is carried out on the MATLAB platform, and experimental results are compared across several deep learning (DL) models.
Intravenous methadone in perioperative acute and chronic pain management in Chinese adult cardiac surgical patients: a protocol for pilot randomised controlled trial
Authors: WONG Henry Man Kin , Wong Wai Tat , Liu XiaoDong , Li Ara Cheuk Yin , Au Sylvia Siu Wah , WONG Randolph Hung Leung 
Published: March 2024

Abstract
Background
Postoperative pain is significant in cardiac surgical patients. Perioperative analgesia with intermittent administration of opioids can result in significant fluctuations in serum opioid concentrations. Methadone should provide a rapid onset and long-term pain relief upon a single intravenous dose at induction of anaesthesia, and may reduce chronic postsurgical pain (CPSP) in cardiac surgical patients. The feasibility of using intravenous methadone in Chinese cardiac surgical patients, and its effect on acute and chronic pain management after cardiac surgery will be evaluated.
Methods
A single-centre, prospective, randomized-controlled pilot study. Adult cardiac surgical patients will be randomized to receive either methadone 0.2mg/kg (maximum dose 20mg) or equipotent dose of morphine at induction of anaesthesia. Patient-controlled analgesia morphine protocol, oral paracetamol and dihydrocodeine will be given for postoperative analgesia. Venous blood sampling for plasma methadone concentration will be obtained at regular intervals from study drug infusion to 96 hours after administration. The primary outcomes will be the recruitment and attrition rate, complications from methadone, and the perceived trial feasibility. Secondary outcomes include time weaned to spontaneous breathing trial, morphine consumption within 24 hours and 72 hours after surgery, time to first morphine rescue, postoperative pain score, patient satisfaction, length of stay in ICU and hospital. Side effects of opioids including sedation, nausea and vomiting, and time to first bowel opening will be recorded. CPSP will be assessed with Neuropathic Pain Scale and Pain Catastrophizing Scale at 3 and 6 months after surgery.
Discussion
There have not been many randomized controlled trials describing the use of intravenous methadone in cardiac surgical patients, and none in Chinese population. Results from this study will lay the foundation for future large-scale studies on intravenous methadone use in cardiac surgery, which has the potential to improve the quality of recovery by optimizing acute and chronic pain management. This is also the first study to demonstrate perioperative changes in plasma concentration of methadone in cardiac surgery.
Ethics and dissemination
The Joint CUHK-NTEC Clinical Research Ethics Committee approved the study protocol (CREC Ref. No.: 2022.636-T). The findings will be presented at scientific meeting, peer-reviewed journals and to study participants.
Trial registration number
NCT05913284
Trial registration URL
https://clinicaltrials.gov/study/NCT05913284
Creativity and Entrepreneurial Orientation in Early-Stage Tech Startups: A Cross-Countries Study in Australia, New Zealand, and Singapore for Sustainable Development
Authors: Magableh Khaled Naser , Kannan Selvi 
Published: March 2024

Abstract

This study shows how early-stage tech entrepreneurs leverage creativity and entrepreneurial orientation (EO) to enhance the odds of their new ventures’ success. A total of 20 entrepreneurs from tech startups in Australia, New Zealand, and Singapore were interviewed using a qualitative approach. Data was collected from semi-structured interviews and analysed using NVivo 12 Plus. The findings reveal the vital role of personal competencies such as storytelling, business skills, and proactive learning in enabling entrepreneurs to exhibit creativity and innovativeness. Interpersonal competencies, including relationship building and risk encouragement, empower entrepreneurs to demonstrate proactiveness and competitive aggressiveness. Managerial competencies, such as creative problem-solving, customer focus, and vision articulation, help entrepreneurs manifest leadership abilities and enhance autonomy and creativity, emphasising their critical role in fostering EO dimensions and creativity among early-stage entrepreneurs. Moreover, the insights gained from this study can contribute to achieving the United Nations Sustainable Development Goals (UNSDGs).
Analysis of mitogenomes from the family Keratoisididae reveals mitonuclear discordance and the presence of unknown open reading frames
Authors: Morrissey Declan , Quattrini Andrea M. , Allcock A. Louise 
Published: March 2024

Abstract

Historically, evolutionary studies have not been able to resolve relationships within Octocorallia but recent advances in genomic techniques have allowed large numbers of Ultra Conserved Elements and exons, collectively referred to as conserved elements, to be extracted from the nuclear genome. Few studies have compared evolutionary histories generated with these conserved elements and with those inferred from complete mitochondrial genomes. We examined the characteristics of 26 complete mitogenomes and constructed both mitochondrial and nuclear (1418 conserved elements) phylogenies of the family Keratoisididae, a prolific group of exclusively deep-sea corals. Relationships among most keratoisidid groups were well supported by the conserved element phylogeny while many relationships were unresolved from mitogenomic inferences. In addition, some incongruences were observed. The position of keratoisidid groups F1 and I4, and the observed polyphyly of D2 in the nuclear inference phylogeny, provide evidence for mitonuclear discordance within the group. Multiple novel Open Reading Frames (ORFs) of unknown function were found in the mitochondrial genome between cob and nad6. These ORFs ranged in size from 84–537 bp and were present in all examined mitogenomes except those assigned to keratoisidid group A1 which only have a 10 bp gap between coding regions. Further investigation is required to determine whether these ORFs are expressed and, if so, what function they have. The presence of mitonuclear discordance within the family indicates that phylogenies constructed with concatenated mitochondrial and nuclear markers may be inappropriate.
T-cell receptor triggering requires inactivation of Lim kinase-1 by Slingshot-1 phosphatase
Authors: Roda-Navarro Pedro , Gómez-Morón Álvaro , Alegre-Gómez Sergio , Ramirez-Muñoz Rocio , Hernaiz-Esteban Alicia , Carrasco-Padilla Carlos , Scagnetti Camila , Aguilar-Sopeña Óscar , García-Gil Marta , Borroto Aldo , Torres-Ruiz Raul , Rodríguez-Perales Sandra , Sanchez-Madrid Francisco , Martin-Cofreces Noa 
Published: March 2024

Abstract

Actin dynamics control early T cell receptor signalling during T cell activation. However, the precise regulation of initial actin rearrangements is not completely understood. Here, we have investigated the regulatory role of the phosphatase Slingshot-1 (SSH1) in this process. Our data show that SSH1 rapidly polarises to nascent cognate synaptic contacts and later relocalises to peripheral F-actin networks organised at the mature synapses. Knockdown of SSH1 expression by CRISPR/Cas9-mediated genome editing or small interfering RNA revealed a regulatory role for SSH1 in CD3ε conformational change, allowing Nck binding and proper downstream signalling and immunological synapse organisation. TCR triggering induced the SSH1-mediated activation of actin dynamics through a mechanism mediated by Limk1 inactivation. These data suggest that during early TCR activation, SSH1 is required for early F-actin rearrangements that mediate initial conformational changes of the TCR, integrin organisation and proximal signalling events for proper synapse organisation.
Development and evaluation of the internal consistency of the Spanish version of the Dentine Hypersensitivity Experience Questionnaire-15 (DHEQ-15)
Authors: D’Eramo Luciana , Vila María Florencia Escalante , Sánchez María Laura , Salgado Pablo Andrés , Rösing Cassiano K , Squassi Aldo 
Published: March 2024

Abstract

Background: Dentine hypersensitivity (DH) is a prevalent yet understudied pain condition that affects millions of people worldwide. Assessing self-reported DH experiences is crucial for research and clinical management. This study aimed to develop and evaluate the internal consistency of the Spanish version of the DHEQ-15, a short, validated questionnaire for this purpose.
Methods: A two-stage approach was employed. The first stage involved cross-cultural adaptation of the DHEQ-15 through forward-backward translation, pilot testing, and expert review. The second stage was a cross-sectional study with 2,530 dental patients who completed the translated DHEQ-15 and answered questions about their overall oral health. Internal consistency was assessed using Cronbach's alpha and item-to-total correlations. A receiver operating characteristic (ROC) curve was used to establish a cutoff point for identifying individuals with significant DH based on their DHEQ-15 score and a dental examination.
Results: The final Spanish DHEQ-15 demonstrated excellent internal consistency, with a Cronbach's alpha of 0.961. All item-to-total correlations were above 0.4, indicating good item discrimination. The ROC curve analysis identified a cutoff point of 26 for the DHEQ-15 score, with an area under the curve of 0.773.
Conclusions: The Spanish DHEQ-15 is a reliable and valid tool for assessing self-reported DH experiences in Spanish-speaking populations. The established cutoffpoint of 26 can assist in identifying individuals with DH who might benefit from clinical intervention. This culturally adapted instrument holds promise for facilitating research, improving clinical management, and ultimately enhancing patient care in DH.
An Integrated Bioremediation Approach for Wastewater Treatment and Contaminated Soil Remediation in a Used Oil Recycling Plant
Authors: Jemli Meryem , Karray Fatma , Mansour Lamjed , Loukil Slim , Bouhdida Rihab , Aleya Sami , Sayadi Sami 
Published: March 2024

Abstract

This work focused on the biotreatment of wastewater and contaminated soil in a used oil recycling plant located in Bizerte.
A Continuous Stirred Tank Reactor (CSTR) and a Trickling Filter (TF) were used to treat stripped and collected wastewater, respectively. The CSTR was started up and stabilized for 90 days. Over the following 170 days, the operational organic loading rates (OLR) of the TF and the CSTR were around 1200 and 3000 mg chemical oxygen demand (COD) L-1 day-1, respectively.
The treatment efficiency was 94% for total petroleum hydrocarbons (TPH), 89.5% for COD, 83.34% for biological oxygen demand (BOD5) and 91.25% for phenol. Treated industrial wastewater from the TF was used for bioaugmentation (BA) of contaminated soil. The BA strategy was compared with natural attenuation (NA) based on the use of tap water. The assessment of the soil took 24 weeks to complete.
The effectiveness of the soil bioaugmentation strategy was confirmed by monitoring of phenolic compounds, aliphatic and polycyclic aromatic hydrocarbons (AH and PAH), heavy metals and germination index (GI). The biodegradation rate of contaminants was improved and the time required for their removal was reduced.
The soil bacterial communities were dominated by species of the genera Mycobacterium, Proteiniphilum, Nocardioides, Luteimicrobium and Azospirillum, which were identified as hydrocarbon and phenol degrading bacteria.
The bioremediation of polluted soils by the treated industrial effluents seems to be an interesting approach for the conservation of water and soil resources.
Investigation on nonlinear dynamics and fatigue damage of a simply supported tube with clearance restriction in tube bundles subjected to two-phase flow
Authors: Yang Shihao , Lai Jiang 
Published: March 2024

Abstract

A mathematical model of a simply supported tube with clearance restriction in an otherwise rigid rotated triangular tube array subjected to two-phase flow was established in this study. The nonlinear vibration responses of the tube bundles system were calculated, and the fatigue damage evaluation were carried. The relationships between the fatigue damage and collision behavior are obtained. The numerical results indicated that the reduced velocity has an obvious effect on the dominant frequency, the collision frequency, and the equilibrium position the system. The nonlinear dynamic characteristics of simply supported tube with clearance restriction in an otherwise rigid rotated triangular tube array may essentially determine the fatigue damage results.
YouTube/ Bilibili/ TikTok Videos as Sources of Medical Information on Laryngeal Carcinoma: Cross-Sectional Content Analysis Study
Authors: Liu ZeYang , Chen YiWen , Lin Ying , Ai MaoMao , Lian DongLing , Zhang YuanHui , Shen YanXiong , Yu Feng 
Published: March 2024

Abstract

Background YouTube, a widely recognized global video platform, is inaccessible in China, where Bilibili and TikTok are popular platforms for long and short videos, respectively. There are many videos related to laryngeal carcinoma on these platforms. This study aims to evaluate the quality of the relevant videos and to analyze audience interaction on YouTube/ Bilibili/ TikTok.
Methods On January 1, 2024, we searched the top 100 videos by default sort order (300 videos in total) with the terms “laryngeal carcinoma” and “throat cancer” on YouTube, “喉癌” on Bilibili and TikTok. Videos were screened for relevance and similarity. Video characteristics were documented, and quality was assessed using the Patient Education Materials Assessment Tool (PEMAT), Video Information and Quality Index (VIQI), Global Quality Score (GQS), and modified DISCERN (mDISCERN).
Results The analysis included 99 YouTube videos, 76 from Bilibili, and 73 from TikTok. Median video lengths were 193s (YouTube), 136s (Bilibili), and 42s (TikTok). TikTok videos demonstrated higher audience interaction, while Bilibili had the lowest ratio of original content (69.7%). Treatment was the most popular topic on YouTube and Bilibili, while that on TikTok was the prognosis. Solo narration was the most common video style across all platforms. Video uploaders were predominantly non-profit organizations (YouTube), self-media (Bilibili), and doctors (TikTok), with TikTok authors having the highest certification rate (83.3%). Video quality, assessed using PEMAT, VIQI, GQS, and mDISCERN, varied across platforms, with YouTube showing the highest scores in general. Videos from professional authors performed better than videos from non-professionals based on the scores of GQS and mDISCERN. Spearman correlation analysis showed no strong relationships between the video quality and the audience interaction.
Conclusions TikTok, a short video platform, despite being more interactive, tends to offer less information and is of lower quality compared to long video platforms. Yet, a greater number of non-professional authors on Bilibili degraded its video quality. Though videos on YouTube are of the best quality, the video quality across all platforms needs enhancement. We need more professional uploaders to ameliorate the video quality related to laryngeal carcinoma.
Improving Data Quality and Information Use through Capacity Building and Mentorship Program in Ethiopia: Best Practices and Lessons Learned
Authors: Belay Hiwot , Demboba Wubshet , Mohammedsanni Afrah , Atnafu Asmamaw , Gutema Keneni , Amare Getasew , Abera Netsanet , Gebeyehu Abebaw 
Published: March 2024

Abstract

Background: The Capacity Building and Mentorship Program (CBMP) is a collaborative initiative of the Federal Ministry of Health of Ethiopia (FMOH) and selected Universities to enhance the Information Revolution Agenda. Recently, the FMOH declared that some CBMP implementations woredas are models. Therefore, assessing the best practices and lessons learned among the model woredas is essential for the success and scalability of the program. This study explores the best practices and lessons learned and their implications for creating a learning health system.
Methods: - A descriptive exploratory case-study design was conducted in four verified model woredas and one town administration across three regions: Amhara, Sidama, and Benishangul-Gumuz of Ethiopia. The study involved interviewing forty-two informants who were purposively selected from the model districts. A semi-structured interview guide was used to explore information on the Performance Monitoring Team (PMT), data management, analysis, visualization and use, capacity building, and infrastructure. The data collected was analyzed thematically using Atlas ti. 8 software.
Results: - Six themes were explored in this study: technical, behavioral, organizational intervention, health information system performance improvement, sustainability, and challenges. Need-based and practical capacity-building training, local resource mobilization, leadership engagement, HIS task audit, HIS accountability framework, reward, and recognition were some of the critical best experiences and lessons to be shared. Besides data visualization and dissemination, the Performance Monitoring Team (PMT) functionality and quality improvement project using strategic problem-solving approaches enhanced the intervention implementation. This study asserted local resource mobilization, leadership engagement, and institutional capacity building as critical factors for the sustainability of existing achievements. However, staff shortage and turnovers, job evaluation grading complaints, and low competency of medical record unit staff were existing challenges affecting the sustainability and scalability of the best experiences and lessons.
Conclusion and recommendation: - Numerous best experiences and lessons are identified among model districts. Need-based and practical HIS capacity-building training, leadership engagement, local resource mobilization, and HIS accountability framework were scalable and replicable best experiences and lessons. However, staff shortage and turnover, local Health Information Technician complaints, and contextual factors must be considered while scaling up to other areas.
Effect of Climate Change and Fear in a Fractional Prey-Predator Model with Crowley and Martin Functional Response
Authors: Assila Chaimaa , Benazza Hafida , Lemnouar Mohamed Reda 
Published: March 2024

Abstract

Global climate change is amplifying with each passing day, notably as rising temperatures increasingly influence ecological relationships. Therefore, a thorough understanding of the connection between temperature and predation is imperative to address the threat of extinction resulting from excessive temperature increases. In this paper, we introduce a fractional prey-predator model incorporating the Caputo fractional operator. Our model considers prey-predator interactions based on Crowley and Martin's functional response, taking into account the fear effect induced by predation. We analyze the non-negativity, existence, uniqueness, and boundedness of solutions within our model, considering both classical and Caputo derivative scenarios. Furthermore, we investigate the local stability of each equilibrium under both integer and fractional order conditions. In particular, we emphasize the global stability of the coexistence positive equilibrium point in both contexts. Our examination considers predation as a time-dependent function, with the temperature function reflecting climate change and elucidating how elevating temperatures contribute to predation. Through numerical simulations, we validate our theoretical findings, explore the impacts of fear on prey behavior and population dynamics, and illustrate how climate change, especially rising temperatures, intricately affects species relationships.
Mathematics Subject Classification: 26A33 , 34C60 , 34D20 , 92D25 , 37N25.