bluuebunny/crossref_metadata_2025_split huggingface dataset:
Buddhism and Romanticism
Authors: Lussier Mark 
Published: August 2006

AbstractAlthough Buddhism was quite likely first encountered by Europeans during the Greek military incursion into Central Asia led by Alexander the Great, complete knowledge of the religion inaugurated by the historical Buddha only emerged into European consciousness during the eighteenth and nineteenth centuries, a temporal period when economic colonialism, enlightenment epistemology, linguistic Orientalism, and emergent romanticism combined to create the conditions for the full flowering of the dharma in Europe. The following essay provides a preliminary analysis of the historical conditions governing phases of punctuated encounters between Europeans and Buddhist cultures and the developing intellectual contexts during the period of romanticism that ultimately led to the emergence and subsequent reception of Buddhism in European literature and philosophy. The opening section of the essay briefly maps critical coincidences between these seemingly disparate systems of thought and practice; the second section thoroughly traces the long history of punctuated encounters that peaks during the romantic period itself; and the third section analyzes the counterflow of textual materials from colonial circumferences like Nepal and Tibet to centers of Orientalist scholarship in Russia, England, France, and Germany and their subsequent reception and assimilation within Western thought.
Film as the New Shakespeare and Film on Shakespeare: Reversing the Shakespeare/Film Trajectory
Authors: Cartmell Deborah 
Published: August 2006

AbstractThis article considers the ultimately successful quest for film to be regarded as, not a mere imitator of literature, but the ‘new literature’, or as Allardyce Nicoll intimates in 1936, ‘the new Shakespeare’. This seemingly persistent conception of film as the new Shakespeare accounts, in part, for long‐standing prejudicial attitudes to literature on screen, including cinematic appropriations of Shakespeare, over the last two centuries.
Gravity-mode pulsations in subdwarf B stars: a critical test of stellar opacity
Authors: Jeffery C. S. , Saio H. 
Published: August 2006

Abstract
The identification of non-radial g-mode oscillations as the cause of variability in cool subdwarf B stars (PG 1716 variables) has been frustrated by a 5000-K discrepancy between the observed and theoretical blue-edge of the instability domain. A major component in the solution to this problem has been identified by (i) using updated Opacity Project (OP) instead of OPAL opacities and (ii) considering an enhancement of nickel, in addition to that of iron, in the driving zone. The reason for this success is that, in OP, the ‘Fe-bump’ contributions from iron and nickel occur at higher temperatures than in OPAL. As well as pointing to a solution of an important problem in stellar pulsation theory, this result provides a critical test for stellar opacities and the atomic physics used to compute them.
Ectoparasitic blow flies (Protocalliphora sp.) and nestling Eastern Bluebirds (Sialia sialis): direct effects and compensatory strategies
Authors: Hannam Kristina 
Published: August 2006

Variation in environmental factors such as parasitism can have direct effects on an organism’s fitness. Because parasites draw resources directly from their hosts, they are expected to have negative effects; however, several nestling host – parasite systems show no evidence of direct effects. Absence of direct effects may be explained by compensation strategies used by parents or nestlings themselves. In this study evidence for both direct effects and compensatory strategies in a blow fly (genus Protocalliphora Hough, 1899) – Eastern Bluebird (Sialia sialis (L., 1758)) system were examined. Nestlings showed no direct effects of blow flies on survival and on size at fledging; however, parasitized broods were significantly anemic. There was no evidence for compensation by parents in the form of brood reduction and there was no support for compensation by nestlings via a hierarchy of tissue preservation. Nestlings did compensate for parasitism by accelerating growth at the end of the nestling period and delaying fledging.
Intermediary metabolism in mudskippers,Periophthalmodon schlosseriandBoleophthalmus boddarti, during immersion or emersion
Authors: Ip Yuen K. , Lim Cheng B. , Chew Shit F. 
Published: August 2006

This study aimed to examine effects of 48 h emersion on intermediary metabolism in the mudskippers Periophthalmodon schlosseri (Pallas, 1770) and Boleophthalmus boddarti (Pallas, 1770). The glycogen content increased significantly, while the lactate content remained unchanged, in the muscle of P. schlosseri during 48 h of emersion. Thus, emersion led to either a decrease in glycogen utilization or an increase in glycogen synthesis. Because there was no change in energy charge, P. schlosseri probably used energy stores other than glycogen during emersion. The phosphofructose kinase-1 (PFK) from the muscle of P. schlosseri became more sensitive to ATP inhibition after 6 h of emersion, indicating that a transient decrease in the glycolytic flux indeed occurred at this locus that led to an increase in glycogen content. In contrast, such phenomena were not observed in the muscle of B. boddarti during 48 h of emersion. Emersion also led to a significant increase in the muscle fructose-2,6-bisphosphate (F26P2) content in P. schlosseri, but not in B. boddarti. Based on results obtained from P. schlosseri undergoing forced exercise, we propose that a correlation may exist between the F26P2content and the utilization of amino acids as an energy source in this mudskipper during emersion.
Do the fastest sperm within an ejaculate swim faster in subordinate than in dominant males of Arctic char?
Authors: Vaz Serrano Jonathan , Folstad Ivar , Rudolfsen Geir , Figenschou Lars 
Published: August 2006

Theoretical models predict that subordinate males should have higher sperm velocity to compensate for their disadvantaged mating role and because they experience sperm competition more frequently than dominant males. Differences in mean velocity between sperm of dominants and subordinates in the predicted direction are also documented for a few species, including the Arctic char, Salvelinus alpinus (L., 1758). Yet, this difference in mean velocity does not imply that the fastest sperm within an ejaculate, which are those most likely to fertilize eggs, swim faster in subordinates than in dominants. We studied the 5% and 10% fastest sperm cells in ejaculates of dominant and subordinate Arctic char. Before individuals attained their status, there were no differences in velocity between the fastest sperm of males that later became dominant or subordinate. Yet, after establishment of social position, subordinates showed significantly higher sperm swimming speed of the fastest cells in the first 30 s post activation (i.e., at 15, 20, and 30 s post activation). Males that became subordinates showed no change in sperm speed of the fast cells compared with those at pre-trial levels, whereas males that became dominant reduced the speed of their sperm (15 s post activation) compared with those at pre-trial levels. Our results suggest that males which attain social dominance are unable to maintain high sperm velocity, even among the small fraction of the fastest cells.
Viral gene expression during the establishment of human cytomegalovirus latent infection in myeloid progenitor cells
Authors: Cheung Allen K. L. , Abendroth Allison , Cunningham Anthony L. , Slobedman Barry 
Published: August 2006

AbstractHuman cytomegalovirus (HCMV) establishes and maintains a latent infection in myeloid cells and can reactivate to cause serious disease in allograft recipients. To better understand the molecular events associated with the establishment of latency, we tracked the virus following infection of primary human myeloid progenitor cells at days 1, 2, 3, 5, and 11. At all time points, the viral genome was maintained in most cells at approximately 10 copies. Infectious virus was not detected, but virus could be reactivated by extended fibroblast coculture. In contrast to wild-type HCMV, the viral genome was rapidly lost from myeloid progenitors infected with ultraviolet (UV)–inactivated virus, suggesting viral gene expression was required for efficient establishment of latency. To identify viral genes associated with the establishment phase, RNA from each time point was interrogated using custom-made HCMV gene microarrays. Using this approach, we detected expression of viral RNAs at all time points. The pattern of expression differed from that which occurs during productive infection, and decreased over time. This study provides evidence that a molecular pathway into latency is associated with expression of a unique subset of viral transcripts. Viral genes expressed during the establishment phase may serve as targets for therapies to interrupt this process.
Wogonin sensitizes resistant malignant cells to TNFα- and TRAIL-induced apoptosis
Authors: Fas Stefanie C. , Baumann Sven , Zhu Jia Yun , Giaisi Marco , Treiber Monika K. , Mahlknecht Ulrich , Krammer Peter H. , Li-Weber Min 
Published: August 2006

AbstractTNFα has previously been used in anticancer therapy. However, the therapeutic application of TNFα was largely limited due to its general toxicity and the fact that it activates the NF-κB–family transcription factors, which are proinflammatory and antiapoptotic. To overcome this problem in vitro, specific NF-κB inhibitors or transcription or protein synthesis inhibitors such as actinomycin D and cycloheximide are usually used in combination to increase TNFα killing of tumor cells. However, these agents also cause harmful side effects in vivo. We show here that wogonin, derived from the popular Chinese herb Huang-Qin, attenuates NF-κB activity by shifting TNFα-induced free radical ·O2– to a more reduced nonradical product, H2O2, and thereby sensitizes TNFα-resistant leukemia cells to TNFα-induced apoptosis. Importantly, wogonin does not affect the viability of normal peripheral blood T cells. Wogonin also sensitizes TRAIL-induced apoptosis. Our data suggest a potential use of wogonin as a TNFα or TRAIL adjuvant for cancer treatment. Our data also demonstrate how a herbal compound enhances killing of tumor cells with reduced side effects compared with other treatments.
Targeting the activation-induced antigen CD137 can selectively deplete alloreactive T cells from antileukemic and antitumor donor T-cell lines
Authors: Wehler Thomas C. , Nonn Marion , Brandt Britta , Britten Cedrik M. , Gröne Mark , Todorova Mariya , Link Irina , Khan Shamsul A. , Meyer Ralf G. , Huber Christoph , Hartwig Udo F. , Herr Wolfgang 
Published: August 2006

AbstractIn HLA-incompatible hematopoietic stem cell transplantation, alloreactive donor T cells recognizing recipient mismatch HLA cause severe graft-versus-host disease (GVHD). Strategies allowing the selective depletion of alloreactive T cells as well as the enhancement of graft-versus-malignancy immunity would be beneficial. We generated donor CD8 T-cell lines in vitro using allogeneic recipient cells mismatched at a single HLA class I allele or haplotype as stimulators. Recipient cells were obtained from acute myeloid leukemias, renal-cell carcinomas, and CD40L-induced B lymphoblasts. Resulting alloreactive T cells were activated by incubating day 21 T-cell cultures with HLA-mismatch transfected K562 cells or recipient-derived fibroblasts. Selective allodepletion (SAD) was subsequently performed by a newly developed immunomagnetic depletion approach targeting the tumor necrosis factor receptor molecule CD137 (4-1BB). Compared with other activation-induced antigens, CD137 showed a superior performance based on a consistently low baseline expression and a rapid up-regulation following alloantigen stimulation. In 15 different SAD experiments, the frequency of alloreactive CD8 T cells was reduced to a median of 9.5% compared with undepleted control populations. The allodepleted T-cell subsets maintained significant antitumor and antiviral CD8 responses. In vitro expansion of tumor-reactive T cells followed by CD137-mediated SAD might enhance the antitumor efficacy of T-cell allografts with lower risk of inducing GVHD.
Sustained alterations in biodistribution of stem/progenitor cells in Tie2Cre+α4f/f mice are hematopoietic cell autonomous
Authors: Priestley Gregory V. , Ulyanova Tatiana , Papayannopoulou Thalia 
Published: August 2006

Abstract
We have generated Tie2Cre+α4f/f mice with documented α4-integrin ablation in hematopoietic and endothelial cells. A prominent feature in this model is a sustained, significant increase in circulating progenitors at levels higher than the levels seen with Tie2Cre+VCAM-1f/f mice. To test whether phenotypic differences are due to contributions by ligands other than VCAM-1 in bone marrow, or to α4-deficient endothelial cells or pericytes, we carried out transplantation experiments using these mice as donors or as recipients. Changes in progenitor biodistribution after transplantation were seen only with α4-deficient donor cells, suggesting that these cells were necessary and sufficient to reproduce the phenotype with no discernible contribution by α4-deficient nonhematopoietic cells. Because several similarities are seen after transplantation between our results and those with CXCR4−/− donor cells, the data suggest that VLA4/VCAM-1 and CXCR4/CXCL12 pathways contribute to a nonredundant, ongoing signaling required for bone marrow retention of progenitor cells during homeostasis.
The risk of dialysis access thrombosis is related to the transforming growth factor–β1 production haplotype and is modified by polymorphisms in the plasminogen activator inhibitor–type 1 gene
Authors: Lazo-Langner Alejandro , Knoll Greg A. , Wells Philip S. , Carson Nancy , Rodger Marc A. 
Published: August 2006

AbstractTransforming growth factor–β1 (TGF-β1) and plasminogen activator inhibitor–type 1 (PAI-1) might play a role in the development of fibrosis and stenosis of hemodialysis vascular accesses. We studied polymorphisms in the TGFβ1 (869T>C; 915G>C), and PAI-1 (4G/5G) genes in 416 hemodialysis patients (107 access thrombosis cases, 309 controls), to determine if they are related to vascular access thrombosis. Three TGF-β1 production haplotypes (low, intermediate, and high) were defined according to the combination of polymorphisms found. The adjusted odds ratio (OR) and 95% confidence interval (CI) for access thrombosis in low TGF-β1 producers was 7.31 (2.15-24.88; P = .001). The interaction between low TGF-β1 production haplotype and the 4G/4G PAI-1 genotype was strongly associated with access thrombosis (adjusted OR 19.3; 95% CI 2.82-132.40; P = .003). Mean access thrombosis–free survival times in years (95% CI) were 14.65 (12.05-17.25), 11.96 (8.67-15.25), and 4.94 (3.06-6.83) in high, intermediate, and low TGF-β1 producers, respectively (P = .044). Analysis of the synergy index and the case-only cross-product supported the presence of an interaction. We concluded that low TGF-β1 production haplotype is a risk factor for hemodialysis access thrombosis and that in the presence of the 4G/4G PAI-1 genotype there is an additional increase in risk.
Chlorite and Illite Compositions from Upper Silurian Rock Salts, Retsof, New York
Authors: Bodine M. W. , Standaert R. R. 
Published: August 2006

AbstractChlorite and illite are the major clay minerals in silicate assemblages from a rock salt bed in the Vernon Formation (Upper Silurian) at Retsof, New York. Textural features and Br content of the salt indicate precipitation from shallow marine brine with no subsequent postdepositional recrystallization. Sample mounting procedure for electron microprobe analysis involves clay particle dispersion, sedimentation, and transferral to a planar silver print surface. The 001 face of the flake, rather than the conventional polished plane, constitutes the analyzed surface. Microprobe analysis of the chlorite (80 grains from four samples) yields a mean aggregate Mg-rich clinochlore composition of
$$(M{g_{4.51}}Fe_{0.23}^ + A{l_{1.21}})(A{l_{1.09}}S{i_{2.91}}){O_{10}}{(OH)_{8,}}$$
which is relatively uniform among grains and among samples. Its unique composition when compared with normal shale chlorites suggests an authigenic origin in the marine evaporite environment. Illite (106 grains from five samples) has a mean aggregate composition of
$${{\rm{K}}_{0.85}}(A{l_{1.61}}Fe_{0.20}^{3 + }M{g_{0.23}})(A{l_{0.76}}S{i_{3.24}}){O_{10}}{(OH)_2}$$
with little variation among samples. The illite is distinctly less degraded than normal shale illite suggesting some recrystallization occurred in the hypersaline environment. Extensive compositional variation among illite flakes within each sample may reflect alteration of several different detrital micaceous minerals. The term hyperhalmyrolysis is introduced to denote mineral reactions which occur in the marine hypersaline environment.Diagenesis effected improved crystallinity and undoubtedly involved isochemical recrystallization of the bulk silicate assemblage. Metasomatism of the assemblage during diagenesis, however, appears to be negligible.
Mössbauer Spectra of Dioctahedral Smectites
Authors: Rozenson I. , Heller-Kallai L. 
Published: August 2006

AbstractMössbauer spectra of 15 smectites were investigated. In these samples, ferric iron occupies both M(1) and M(2) octahedral sites, the distribution being partly determined by the relative covalency of the bonds formed.The quadrupole splittings are linearly related to b−3. They show that Fe3+ octahedra are much more distorted in montmorillonite and beidellite than in nontronite and volkonskoite and that M(1) sites are more prone to change than M(2). Ferrous iron occurs in relatively undistorted octahedra in some otherwise distorted octahedral sheets and vice versa.
Hectorite Complexes with Cu(II) and Fe(II)-1,10-Phenanthroline Chelates
Authors: Berkheiser V. E. , Mortland M. M. 
Published: August 2006

AbstractCharacteristics and properties of complexes of a smectite (hectorite) with 1,10-phenanthroline (phen) chelates with iron or copper were determined by a variety of physical and chemical measurements. The complex ions showed high selectivity for the hectorite surface. Basal spacings of 17.4 Å were produced by Fe(II) or Cu(II) analogues of M(phen)32+ hectorite. Adsorption of gases and vapors by the M(phen)32+ hectorite complex revealed large surface areas and reflected intrinsic characteristics of the complex ions. Lower surface areas were found for copper phen hectorite than iron phen hectorite probably because of the loss of a ligand from the Cu(II) ion. ESR spectra confirmed that appreciable Cu(II) existed as the bis-phen complex under certain conditions. An increase in the oxidation potential of the Fe(phen)32+-Fe(phen)33+ couple above that in pure solvent was noted when these complexes were supported by the mineral surface.
Dissolution of Two Australian Palygorskites in Dilute Acid
Authors: Singer Arieh 
Published: August 2006

AbstractThe dissolution of two relatively pure Australian palygorskites in mild acid was studied. For both palygorskites, Si and Mg releases were linear with respect to added acid. The rate of Si release with acid addition is equal to 0.66 μmol Si for each μmol H+ added in both palygorskites. The corresponding releases of Mg were 1.2 μmol for the Al-poor and 0.47 μmol for the Al-rich minerals. Mg appears to be preferentially released into solution over Si, and both Mg and Fe appear to be preferentially released into solution over Al, suggesting a lower stability of Mg and Fe-rich palygorskites compared to Al-rich varieties. The free energy of formation of one of the palygorskites was estimated as equal to −1143.7 kcal/mol.
Mineralogy of Al-Hasa Desert Soils (Saudi Arabia)
Authors: Aba-Husayn Mansur M. , Sayegh Antoine H. 
Published: August 2006

AbstractX-ray mineralogical examination of the 2–20 μm fraction of oriented samples from a highly calcereous swamp soil and neighbouring Mio-Pliocene strata in Al-Hasa showed a wide range in mineralogy: attapulgite, illite, montmorillonite, chlorite and kaolinite, in decreasing order. Powder X-ray diffraction revealed an abundance of attapulgite, calcite, quartz and in a few samples, traces of dolomite, Fe-oxides, feldspars and gypsum.The soils are believed to have been formed by deposition of highly calcareous wind-borne silt particles in an already formed swamp. The surface and subsurface horizons are underlain by an organic residue layer, 30–50 cm thick, containing 14–36% organic matter. The whole profile sits on hard, impervious, sedimentary layers that mineralogically resemble some strata of the outcrop.Attapulgite and illite are the most abundant and common clay minerals in the soils and strata, but are most pronounced in the latter. Attapulgite not only occurs in Al-Hasa, but is widely distributed in the Arabian Peninsula; from east of the Mediterranean through the deserts of Syria and Iraq down to eastern Saudi Arabia, where it occurs only in association with limestone parent material. In this area of extreme aridity (Al-Hasa), the origin of the minerals and their relative abundance is believed to be associated with the source of sediment since minimum alteration seems to have taken place after deposition.
Internal Surface Area of Wyoming Bentonite from Swelling Relationships
Authors: Fink D. H. 
Published: August 2006

AbstractThe internal surface area of Na-Wyoming bentonite was determined for linearly swelling pastes, using a physically based equation which describes such swelling. Information required is simply the linear relationship between interplatelet spacing, determined by X-ray powder diffraction, vs total water content determined gravimetrically. However, before the three-unknown parameter equation can be so applied, that portion of external-pore water, which normally increases linearly commensurately as interstitial water increases, must be decreased to zero. This was accomplished by adding dilute quantities of NaCl salt to the clay-paste system to decrease the attractive forces between positive-edge and negative-face sites, and stirring vigorously to further destroy the card-house structure and align the clay platelets.