bluuebunny/crossref_metadata_2025_split huggingface dataset:
A publication power approach for identifying premier information systems journals
Authors: Holsapple Clyde W. 
Published: December 2007

AbstractStressing that some universities have adopted unrealistic requirements for tenure of information systems (IS) faculty members, a recent editorial in MIS Quarterly contends that the group of premier IS journals needs to be generally recognized as having more than just two members. This article introduces the publication power approach to identifying the premier IS journals, and it does indeed find that there are more than two. A journal's publication power is calculated from the actual publishing behaviors of full‐time, tenured IS faculty members at a sizable set of leading research universities. The underlying premise is that these researchers produce excellent work, collectively spanning the IS field's subject matter, and that the greatest concentrations of their collective work appear in highest visibility, most important journals suitable for its subject matter. The new empirically based approach to identifying premier IS journals (and, more broadly, identifying journals that figure most prominently in publishing activity of tenured IS researchers) offers an attractive alternative to promulgations by individuals or cliques (possibly based on outdated tradition or vested interests), to opinion surveys (subjective, possibly ill‐informed, vague about rating criteria, and/or biased in various ways), and to citation analyses (which ignore semantics of references and, in the case of ISI impact factors, have additional problems that cast considerable doubt on their meaningfulness within the IS field and its subdisciplines). Results of the publication power approach can be applied and supplemented according to needs of a particular university in setting its evaluation standards for IS tenure, promotion, and merit decisions.
Trust in digital information
Authors: Kelton Kari , Fleischmann Kenneth R. , Wallace William A. 
Published: December 2007

AbstractTrust in information is developing into a vitally important topic as the Internet becomes increasingly ubiquitous within society. Although many discussions of trust in this environment focus on issues like security, technical reliability, or e‐commerce, few address the problem of trust in the information obtained from the Internet. The authors assert that there is a strong need for theoretical and empirical research on trust within the field of information science. As an initial step, the present study develops a model of trust in digital information by integrating the research on trust from the behavioral and social sciences with the research on information quality and human– computer interaction. The model positions trust as a key mediating variable between information quality and information usage, with important consequences for both the producers and consumers of digital information. The authors close by outlining important directions for future research on trust in information science and technology.
Authority and ranking effects in data fusion
Authors: Spoerri Anselm 
Published: December 2007

AbstractThis paper provides empirical support for some of the key assumptions guiding the design of data fusion methods. It computes and analyzes the overlap structures between the search results of retrieval systems that participated in the short, long, and manual tracks in TREC 3, 6, 7, and 8 to examine what can be learned to infer a document's probability of being relevant. This paper shows that the potential relevance of a document increases exponentially as the number of systems retrieving it increases—called the Authority Effect. It also shows that documents higher up in ranked lists and found by more systems are more likely to be relevant—called the Ranking Effect. A contribution of this paper is that it shows that the Authority and Ranking Effects can be observed regardless of whether a query is generated manually or automatically and short or long queries are used. Further, it is illustrated that the Authority and Ranking Effects can be observed if the result sets of random groupings of five retrieval systems are compared and only the top 50 results are used in the overlap computation. Also discussed is how the Authority and Ranking Effects can help explain why major data fusion methods perform well.
A Dicationic Organoplatinum(II) Complex Containing a Bridging 2,5‐Bis‐(4‐ethynylphenyl)‐[1,3,4]oxadiazole Ligand Behaves as a Phosphorescent Gelator for Organic Solvents
Authors: Lu Wei , Law Yuen‐Chi , Han Jie , Chui Stephen Sin‐Yin , Ma Dik‐Lung , Zhu Nianyong , Che Chi‐Ming 
Published: December 2007

AbstractA dicationic platinum(II) terpyridyl complex, [(tBu3tpy)Pt(OXD)Pt(tBu3tpy)](PF6)2 (tBu3tpy=4,4′,4“‐tri‐tert‐butyl‐2,2′:6′,2”‐terpyridyl, OXD=2,5‐bis(4‐ethynylphenyl)[1,3,4]oxadiazole) formed phosphorescent organogels in acetonitrile or in a mixture of acetonitrile and alcohol. The structure and properties of these emissive gels were analyzed by polarizing optical and confocal laser scanning microscopy, and by variable‐temperature 1H NMR, UV/Vis, and emission spectroscopy. Dry gels were studied by scanning electron microscopy, powder X‐ray diffraction (PXRD), and small‐angle X‐ray scattering (SAXS). SEM images of the dry gel revealed a network of interwoven nanofibers (diameter 12–60 nm, length>5 μm). Intermolecular π–π interactions between the [(tBu3tpy)PtC≡C] moieties could be deduced from the variable 1H NMR spectra. The PXRD and SAXS data showed that the assembly of the gelator could be represented by a rectangular 2D lattice of 68 Å × 14 Å. The ability of the complex to gelate a number of organic solvents is most likely due to intermolecular π–π interactions between the [(tBu3tpy)PtC≡C] moieties.
DC motor speed control methods using MATLAB/Simulink and their integration into undergraduate electric machinery courses
Authors: Ayasun Saffet , Karbeyaz Gültekin 
Published: December 2007

AbstractThis paper describes the MATLAB/Simulink realization of the DC motor speed control methods, namely field resistance, armature voltage and armature resistance control methods, and feedback control system for DC motor drives. These simulation models are developed as a part of a software laboratory to support and enhance undergraduate electric machinery courses at Nigde University, Nigde, Turkey. © 2007 Wiley Periodicals, Inc. Comput Appl Eng Educ 15: 347–354, 2007; Published online in Wiley InterScience (www.interscience.wiley.com); DOI 10.1002/cae.20151
Hypervalent Silicon versus Carbon: Ball‐in‐a‐Box Model
Authors: Pierrefixe Simon C. A. H. , Fonseca Guerra Célia , Bickelhaupt F. Matthias 
Published: December 2007

AbstractWhy is silicon hypervalent and carbon not? Or why is [ClCH3Cl]− labile with a tendency to localize one of its axial CCl bonds and to largely break the other one, while the isostructural and isoelectronic [ClSiH3Cl]− forms a stable pentavalent species with a delocalized structure featuring two equivalent SiCl bonds? Various hypotheses have been developed over the years focusing on electronic and steric factors. Here, we present the so‐called ball‐in‐a‐box model, which tackles hypervalence from a new perspective. This model reveals the key role of steric factors and provides a simple way of understanding the above phenomena in terms of different atom sizes. Our bonding analyses are supported by computation experiments in which we probe, among other things, the shape of the SN2 potential‐energy surface of Cl− attacking a carbon atom in the series of substrates CH3Cl, .CH2Cl, ..CHCl, and ...CCl. Our findings for ClCH3Cl− and ClSiH3Cl− are generalized to other Group 14 central atoms (Ge, Sn, and Pb) and axial substituents (F).
Ethenolysis of Methyl Oleate in Room‐Temperature Ionic Liquids
Authors: Thurier Cyril , Fischmeister Cédric , Bruneau Christian , Olivier‐Bourbigou Hélène , Dixneuf Pierre H. 
Published: December 2007

AbstractUnsaturated vegetable oils are an attractive renewable feedstock, and the selective cleavage of unsaturated fatty esters is an important transformation in this respect. The efficient and selective cross‐metathesis of methyl oleate with ethylene was achieved under mild conditions with ruthenium‐alkylidene catalysts in toluene and room‐temperature ionic liquids (RTILs) to give two important chemical intermediates, 1‐decene and methyl 9‐decenoate, without double‐bond migration. As recovery of the catalyst is an important target with respect to industrial applications, catalyst recycling studies were also carried out in RTILs with the first‐generation Hoveyda catalyst.
A Bis(C60)–Bis(phthalocyanine) Nanoconjugate: Synthesis and Photoinduced Charge Transfer
Authors: Kahnt Axel , Quintiliani Maurizio , Vázquez Purificación , Guldi Dirk M. , Torres Tomás 
Published: December 2007

AbstractA novel dimeric phthalocyanine–C60 nanoconjugate, consisting of a bisphthalocyanine core to which two fullerenes are attached, has been prepared. The synthetic strategy implemented the preparation of a diformyl butadiynyl‐bridged bisphthalocynaninatozinc(II) complex by means of palladium‐catalyzed cross‐coupling reactions and subsequent dipolar cycloaddition reactions. Photophysical experiments confirm that an intramolecular electron transfer, namely, from the photoexcited ZnPc moiety to the electron‐accepting C60 unit, governs the overall photoreactivity of the nanoconjugate. Through‐space charge‐transfer interactions facilitated by the close proximity of the ZnPc and the C60 moieties play a decisive role in determining the lifetimes of the charge‐separated state which range from 10−10 to 10−9 seconds.
A Highly Active Aqueous Olefin Metathesis Catalyst Bearing a Quaternary Ammonium Group
Authors: Gułajski Łukasz , Michrowska Anna , Narożnik Joanna , Kaczmarska Zuzanna , Rupnicki Leszek , Grela Karol 
Published: December 2007

AbstractA polar olefin metathesis catalyst that bears a quaternary ammonium group was prepared from commercially available reagents. The electron‐withdrawing quaternary ammonium group not only activates the Ru catalyst electronically but at the same time makes the catalyst more hydrophilic. The catalyst can therefore be efficiently used both in traditional media, such as dichloromethane and toluene, as well as in technical‐grade alcohols, alcohol–water mixtures and in neat water. Various metathesis reactions, including ring‐closing, cross‐ and enyne metathesis, were conducted in these solvents in the presence of air. In addition, the Ru catalyst can act as an inisurf (initiator and surfactant) molecule, promoting metathesis under heterogeneous aqueous conditions.
Differential growth and multicellular villi direct proepicardial translocation to the developing mouse heart
Authors: Rodgers Laurel S. , Lalani Sofia , Runyan Ray B. , Camenisch Todd D. 
Published: December 2007

AbstractIn the mammalian system the proepicardium (PE) arises from mesothelium of the septum transversum before translocation to the heart where it forms the epicardium and progenitor cells of the coronary vessels. Despite its importance, the process in which PE cells translocate to the myocardium in mammals is not well defined. The current paradigm states that cellular cysts of PE float across the pericardial space and contact the outer surface of the myocardium. This mechanism does not provide a satisfactory explanation for the directionality or localization of PE migration. To better define PE migration, we performed a detailed study of mouse PE development. We provide thorough documentation that redefines the size of the PE migratory field and the mechanism of migration. Our new model incorporates differential growth and direct contact between multicellular PE villi and the myocardium as mechanisms in formation of the epicardium. Developmental Dynamics 237:145–152, 2008. © 2007 Wiley‐Liss, Inc.
The Use of Solid‐Phase Synthesis Techniques for the Preparation of Peptide–Metal Complex Conjugates
Authors: Dirscherl Georg , König Burkhard 
Published: December 2007

AbstractThis microreview summarizes recent reports on the preparation of metal complex peptide conjugates by solid‐phase synthesis methods. Procedures for such conjugates are in many cases different from standard solid‐phase peptide synthesis protocols. Specific advantages of general strategies, the synthesis of peptide–ligand conjugates and complexation with excess metal ions on solid support or the incorporation of previously prepared metal complex amino acid derivatives are discussed.(© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2008)
Erratum: Evaluation of Bayesian models for focused clustering in health data
Authors: Ma Bo , Lawson Andrew B. , Liu Yuan 
Published: December 2007

AbstractVolume 18, Issue 8, Pages 871–887 (December 2007)DOI: 10.1002/env.850The above paper was published including an error. Within the ‘Acknowledgement’ Section on page 14, the NIH grant number is incorrect. The correct number should be as follows: NIH 1R01CA095979‐2.
Accuracy of technetium‐99m SPECT‐CT hybrid images in predicting the precise intraoperative anatomical location of parathyroid adenomas
Authors: Harris Luke , Yoo John , Driedger Albert , Fung Kevin , Franklin Jason , Gray Daryl , Holliday Ronald 
Published: December 2007

AbstractBackground.This study evaluated the accuracy of single photon emission computed tomography (SPECT)‐CT imaging for the preoperative localization of parathyroid adenomas.Methods.This study included both a quantitative and qualitative accuracy measure. The quantitative measure was the distance between the location of the adenoma on the SPECT‐CT scan and the location of the adenoma intraoperatively. Qualitatively, surgeons were asked whether or not the adenoma was in the exact location predicted by the SPECT‐CT scan. The time from initial incision to identification of the parathyroid was recorded. Patients referred to London Health Sciences Centre for a suspected parathyroid adenoma were eligible for this study.Results.Twenty‐three patients participated in this study. Eighteen (78.3%) had a single adenoma, 2 (8.7%) had double adenomas, and 3 (13.0%) had multiglandular hyperplasia. SPECT‐CT correctly detected and localized 16 of 18 (88.9%) cases of single parathyroid adenomas. The mean distance between the location of the adenoma on the SPECT‐CT scan and the location of the adenoma intraoperatively was 16.3 mm (95% ≤ 19.0 mm). For single adenomas, the median time from skin incision to identification was 14 minutes (range, 8–40 minutes). The preoperative detection and localization of a single focus of sestamibi uptake yielded a parathyroid adenoma in the specified location in 80.0% of cases (95% CI, 97.4–66.5%).Conclusions.SPECT‐CT predicted the intraoperative location of a single parathyroid adenoma within 19.0 mm with 95% confidence. The correct detection and localization of multiglandular disease remains difficult. © 2007 Wiley Periodicals, Inc. Head Neck, 2008
Prolonged glucocorticoid treatment decreases cannabinoid CB1 receptor density in the hippocampus
Authors: Hill Matthew N. , Carrier Erica J. , Ho W.‐S. Vanessa , Shi Leyu , Patel Sachin , Gorzalka Boris B. , Hillard Cecilia J. 
Published: December 2007

AbstractExperimental studies indicate a bidirectional, functional relationship between glucocorticoids and the endocannabinoid system; however, the effects of repeated glucocorticoid treatment on the endocannabinoid system have not been examined. In this study, we treated male rats with either a single dose or a 21‐day course of treatment with corticosterone (20 mg/kg) and measured hippocampal cannabinoid CB1 receptor expression and endocannabinoid content. The 21‐day, but not the single, administration of corticosterone significantly reduced both the binding site density and amount of protein of the hippocampal cannabinoid CB1 receptor without affecting affinity for the CB1 receptor agonist, [3H]CP55940. With regard to hippocampal endocannabinoid content, acute corticosterone treatment resulted in a significant reduction in anandamide but did not affect 2‐arachidonylglycerol, while repeated corticosterone treatment did not alter content of either anandamide or 2‐arachidonylglycerol. These data support the hypothesis that the cannabinoid CB1 receptor is under negative regulation by glucocorticoids in the hippocampus, and suggest that hippocampal cannabinoid CB1 receptor signaling could be reduced under conditions associated with hypersecretion of glucocorticoids, such as chronic stress. © 2007 Wiley‐Liss, Inc.
Leptin and leptin receptor genotypes and colon cancer: Gene–gene and gene–lifestyle interactions
Authors: Slattery Martha L. , Wolff Roger K. , Herrick Jennifer , Caan Bette J. , Potter John D. 
Published: December 2007

AbstractLeptin may play an important role in colorectal cancer because of its role in energy balance, insulin and inflammation. We evaluated the LEP rs2167270 (19 G > A) and rs7799039 (−2548 G > A) polymorphisms and the leptin receptor, LEPR rs6588147 (located in intron 2), polymorphism with risk of developing colon cancer in a study of 1,567 cases and 1,965 controls. We evaluated the effects of the polymorphisms with body mass index (BMI), recent use of aspirin/NSAIDs and genetic variations in genes related to insulin signaling pathways including insulin‐like growth factor 1 (IGF1), insulin‐like growth factor binding protein 3 (IGFBP3), and insulin‐related substrates 1 and 2 (IRS1, IRS2) and the vitamin D receptor (VDR). We observed a slight reduction in colon cancer risk with the AA LEP rs2167270 genotype (OR 0.79 95% CI 0.64, 0.98) and although not reaching statistical significance, with the combined GG LEP rs2167270 and GG LEPR rs6588147 (OR 0.70, 95% CI 0.49, 1.02) genotypes. BMI did not interact with any of these polymorphisms to alter colon cancer risk. However, recent aspirin/NSAID use significantly interacted with both LEP polymorphisms. Likewise, variants of IGF1 and IRS2 interacted with the LEP rs2167270 polymorphism. VDR polymorphisms interacted with all LEP and LEPR polymorphisms. These data support an association between LEP and colon cancer. They also suggest that the mechanisms linking leptin to colon cancer may be independent of energy balance. © 2007 Wiley‐Liss, Inc.
Frequent epigenetic inactivation of hSRBC in gastric cancer and its implication in attenuated p53 response to stresses
Authors: Lee Jin‐Hee , Byun Do‐Sun , Lee Min‐Goo , Ryu Byung‐Kyu , Kang Min‐Ju , Chae Kwon‐Seok , Lee Kil Yeon , Kim Hyo‐Jong , Park Heonyong , Chi Sung‐Gil 
Published: December 2007

AbstracthSRBC is a putative tumor suppressor located at 11p15.4, at which frequent genomic loss has been observed in several human malignancies. To explore the candidacy of hSRBC as a suppressor of gastric tumorigenesis, we analyzed the expression and mutation status of hSRBC in gastric tissues and cell lines. hSRBC transcript was expressed in all normal and benign tumor tissues examined, but undetectable or very low in 73% (11/15) cancer cell lines and 41% (46/111) primary tumors. Loss or reduction of hSRBC expression was tumor‐specific and correlated with stage and grade of tumors. While allelic loss or somatic mutations of the gene were infrequent, its expression was restored in tumor cells by 5‐aza‐2′‐deoxycytidine treatment and aberrant hypermethylation of 23 CpG sites in the promoter region showed a tight association with altered expression. Transient or stable expression of hSRBC led to a G1 cell cycle arrest and apoptosis of tumor cells, and strongly suppresses colony forming ability and xenograft tumor growth. In addition, hSRBC elevated apoptotic sensitivity of tumor cells to genotoxic agents, such as 5‐FU, etoposide and ultraviolet. Interestingly, hSRBC increased the protein stability of p53 and expression of p53 target genes, such as p21Waf1, PUMA and NOXA, while hSRBC‐mediated cell cycle arrest and apoptosis were abolished by blockade of p53 function. Our findings suggest that hSRBC is a novel tumor suppressor whose epigenetic inactivation contributes to the malignant progression of gastric tumors, in part, through attenuated p53 response to stresses. © 2007 Wiley‐Liss, Inc.
HPP1‐mediated tumor suppression requires activation of STAT1 pathways
Authors: Elahi Abul , Zhang Li , Yeatman Timothy J. , Gery Sigal , Sebti Said , Shibata David 
Published: December 2007

AbstractHPP1 is a recently discovered gene that is epigenetically silenced in a number of tumor types, suggesting a potential role as a tumor suppressor. However, whether HPP1 has tumor suppressor activity is not clearly known. We have sought to investigate the effects of HPP1 on tumor growth and survival and to identify signaling pathways that mediate HPP1's mechanism of action. Forced expression of HPP1 into HCT116 colon cancer cell lines blocked the ability of HCT116 tumors to grown in vivo in nude mice. In cell culture, ectopic expression of HPP1 induces apoptosis and potently inhibits soft agar colony formation. HPP1 overexpression was also associated with a moderate reduction in in vitro proliferation characterized by an accumulation of cells in the G0/G1 phase of the cell cycle. Microarray analysis revealed that ectopic expression of HPP1 resulted in a dramatic upregulation of STAT1 as well as a large number of associated interferon‐inducible genes. RNA interference‐mediated abrogation of STAT1 reversed HPP1's antiproliferative effects. We conclude that HPP1 demonstrates tumor suppressive and pro‐apoptotic activity, both in vitro and in vivo. Coupled with its inactivation in a number of tumor types, our data provides evidence to support the role of HPP1 as a tumor suppressor gene. Moreover, activation of the STAT1 pathway likely represents the principal mediator of HPP1's tumor suppressive properties. © 2007 Wiley‐Liss, Inc.
SPARC modulates the proliferation of stromal but not melanoma cells unless endogenous SPARC expression is downregulated
Authors: Haber Cynthia López , Gottifredi Vanesa , Llera Andrea S. , Salvatierra Edgardo , Prada Federico , Alonso Leonardo , E. Helene Sage , Podhajcer Osvaldo L. 
Published: December 2007

AbstractCell interaction with the extracellular matrix (ECM) has profound influence in cancer progression. The secreted protein, acidic and rich in cysteine (SPARC) a component of the ECM, impairs the proliferation of different cell types and modulates tumor cell aggressive features. This apparent paradox might result either from the biochemical properties of the different SPARC sources or from differential responses of malignant and stromal cells to SPARC. To test these hypotheses, we purified SPARC secreted by melanoma cells (hMel‐SPARC) and compared its activity with different recombinant SPARC preparations, including a new one produced in insect cells. All 5 SPARC species were effective in inhibiting bovine aortic endothelial cell proliferation, adhesion and migration. We then used the melanoma‐derived protein to assess SPARC effect on additional cell types. hMel‐SPARC greatly impaired the proliferation of both normal and transformed human endothelial cells and exerted a moderate biphasic effect on human fetal fibroblasts proliferation, irrespective of their endogenous SPARC levels. However, SPARC had no effect on the proliferation of several human cancer cell lines regardless of their endogenous levels of SPARC expression. Importantly, downregulation of SPARC levels in melanoma cells using either an antisense RNA or a shRNA against SPARC sensitized them to hMel‐SPARC addition in proliferation and migration assays, suggesting that malignant cells developed a SPARC‐resistance mechanism. This was not a general resistance to growth suppressing agents, as melanoma cells with restricted SPARC expression were more resistant to chemotherapeutic agents. Thus, malignant cells expressing or not expressing SPARC developed alternative mechanisms that, in contrary to stromal cells, rendered them SPARC‐insensitive. © 2007 Wiley‐Liss, Inc.