bluuebunny/crossref_metadata_2025_split huggingface dataset:
Late Miocene igneous rocks of Samos: the role of tectonism in petrogenesis in the southeastern Aegean
Authors: Pe-Piper G. , Piper D. J. W. 
Published: December 2007

Abstract
Late Miocene igneous rocks of Samos, in the southeastern Aegean Sea, comprise monzodiorite and minor granite of the Katavasis complex, trachyte and rhyolite of the Ambelos volcanic centre, and bimodal basalt–rhyolite at basin margins. Six new K–Ar ages, together with existing geochronology and biostratigraphy, show that the Katavasis complex and Ambelos centre date from 10–11 Ma and basalt–rhyolite from 8 Ma, correlating with cooling ages for the Katavasis complex and an unconformity in the basin fill. Monzodiorite, granite, trachyte and basalt all have similar radiogenic isotopes. Monzodiorite and basalt have similar trace element compositions and could result from 5–10% partial melting of enriched garnet lherzolite in the subcontinental lithosphere. Variations in trace elements suggest that trachyte and monzodiorite evolved by fractional crystallization from a parental magma similar to the younger basalt. The Katavasis and Ambelos rocks were synchronous with regional extension and listric faulting, which created opportunities for mid-crustal magma chambers and magma fractionation. Basalt extrusion was synchronous with the onset of north–south strike-slip faulting, which permitted more rapid transfer of magma to the surface. Late Miocene strike-slip faulting propagated from north to south in western Anatolia and the southeastern Aegean Sea, providing pathways for different types of mantle melts.
From syn- to post-orogenic Tertiary extension in the north Aegean region: constraints on the kinematics in the eastern Rhodope–Thrace, Bulgaria–Greece and the Biga Peninsula, NW Turkey
Authors: Bonev N. , Beccaletto L. 
Published: December 2007

Abstract
The Aegean region experienced back-are extension related to the Hellenic subduction system at least from the latest Oligocene to the present. We document Tertiary extension-related kinematics in the north Aegean, in the eastern Rhodope–Thrace of Bulgaria–Greece and the Biga Peninsula of NW Turkey. A regionally consistent NNE–SSW- to NE–SW-oriented kinematic direction, delineated in both areas by stretching lineations and associated ductile–brittle shear fabrics in exhumed metamorphic domes beneath detachments, suggests that they were kinematically coupled during the Tertiary extension. This kinematic framework, combined with regional geochronological data and the stratigraphic record in hanging-wall supradetachment basins, defines an extensional history that includes syn- and post-orogenic episodes from Paleocene to Miocene times. Paleocene–early Eocene synorogenic extension in the Kemer micaschists of the northern Biga Peninsula and in the Kesebir–Kardamos dome in Rhodope–Thrace accommodated gravitationally induced hinterland-directed exhumation of the orogenic stack, coeval with the closure of the Vardar Ocean. Then, following collision within the region, it was succeeded by latest Oligocene–Early Miocene extension as recorded in the Kazdaǧ Massif in the southern Biga Peninsula, which overlaps the Aegean back-arc post-orogenic extension, widely recognized in the central Aegean and southern Greek Rhodope. The protracted record of extension is interpreted to reflect progressive exhumation of the orogenic wedge along the Eurasian plate margin. Southward migration of extension and magmatism across the study areas accounts for sequential shift and roll-back of the subduction boundary at that margin, from the latest Cretaceous in the Rhodope to its present position at the Hellenic trench. The results allow recognition of the investigated areas as an important extensional domain in the north Aegean region, which underwent Tertiary syn- and post-orogenic extension.
Geodetic constraints on kinematics of southwestern Bulgaria from GPS and levelling data
Authors: Georgiev I. , Dimitrov D. , Belijashki T. , Pashova L. , Shanov S. , Nikolov G. 
Published: December 2007

Abstract

Southwestern Bulgaria belongs to the southern marginal parts of the central Balkan neotectonic region and borders the northern side of the highly seismic north Aegean region. The recent horizontal and vertical motion of the tectonic structures is controlled primarily by the collision stage, caused by continuing ENE palaeosubduction in the Ionian and Adriatic seas and extensional processes northwards of the North Aegean Trough. The present-day generation of small to moderate seismicity and crustal faulting suggests that the complex tectonic processes in the SW Bulgaria region are active. To monitor and study the tectonic deformation in SW Bulgaria, a global positioning system (GPS) network was established in early 2001. Analysis of GPS data from 1996 to 2004 resulted in a horizontal velocity field representing active surface deformations. Horizontal velocities at 38 GPS sites with respect to stable Eurasia are obtained. A new map of the recent vertical velocities is compiled, based on recomputed data from the repeated precise levelling for the period 1929–1991. We obtained evidence of recent active faulting. Based on the geological and geodetic data the SW Bulgaria is separated into five blocks with homogeneous kinematic behaviour. The average motion of each block varies from 1.3 to 3.4 mm a
−1
, and the whole region velocity is
c
. 1.8±0.7 mm a
−1
in a direction N154° with respect to stable Eurasia. Geodetic data correlate well with the geological data on neotectonic motions in SW Bulgaria.
Shear velocity structure in the Aegean region obtained by joint inversion of Rayleigh and Love waves
Authors: Karagianni E. E. , Papazachos C. B. 
Published: December 2007

Abstract

We present a shear velocity model of the crust and uppermost mantle under the Aegean region by simultaneous inversion of Rayleigh and Love waves. The database consists of regional earthquakes recorded by portable broadband three-component digital stations that were installed for a period of 6 months in the broader Aegean region. For each epicentre–station ray path group velocity dispersion curves are measured using appropriate frequency time analysis (FTAN). The dispersion measurements for more than 600 Love wave paths have been used. We have also incorporated previous results for
c
. 700 Rayleigh wave paths for the study area. The single-path dispersion curves of both waves were inverted to regional group velocity maps for different values of period (6–32 s) via a tomographic method. The local dispersion curves of discrete grid points for both surface waves were inverted nonlinearly to construct 1D models of shear-wave velocity v. depth. In most cases the joint inversion of Rayleigh and Love waves resulted in a single model (from the multiple models compatible with the data) that could interpret both Rayleigh and Love wave data. Around 60 local dispersion curves for both Rayleigh and Love waves were finally jointly inverted. As expected, because of the complex tectonic environment of the Aegean region the results show strong lateral variations of the S-wave velocities for the crust and uppermost mantle. Our results confirm the presence of a thin crust typically less than 28–30 km in the whole Aegean Sea, which in some parts of the southern and central Aegean Sea becomes significantly thinner (20–22 km). In contrast, a large crustal thickness of about 40–45 km exists in western Greece, and the remaining part of continental Greece is characterized by a mean crustal thickness of about 35 km. A significant sub-Moho upper mantle low-velocity zone (LVLmantle) with velocities as low as 3.7 km s
−1
, is clearly identified in the southern and central Aegean Sea, correlated with the high heat flow in the mantle wedge above the subducted slab and the related active volcanism in the region. The results obtained results are compared with independent body-wave tomographic information on the velocity structure of the study area and exhibit a generally good agreement, although significant small-scale differences are also identified.
A model for the Hellenic subduction zone in the area of Crete based on seismological investigations
Authors: Meier T. , Becker D. , Endrun B. , Rische M. , Bohnhoff M. , Stöckhert B. , Harjes H.-P. 
Published: December 2007

Abstract

The island of Crete represents a horst structure located in the central forearc of the retreating Hellenic subduction zone. The structure and dynamics of the plate boundary in the area of Crete are investigated by receiver function, surface wave and microseismicity using temporary seismic networks. Here the results are summarized and implications for geodynamic models are discussed. The oceanic Moho of the subducted African plate is situated at a depth of about 50–60 km beneath Crete. The continental crust of the overriding Aegean lithosphere is about 35 km thick in eastern and central Crete, and typical crustal velocities are observed down to the upper surface of the downgoing slab beneath western Crete. A negative phase at about 4 s in receiver functions occurring in stripes parallel to the trend of the island points to low-velocity slices within the Aegean lithosphere. Interplate seismicity is spread out about 100 km updip from the southern coastline of Crete. To the south of western Crete, this seismically active zone corresponds to the inferred rupture plane of the magnitude 8 earthquake of
ad
365. In contrast, interplate motion appears to be largely aseismic beneath the island. The coastline of Crete mimics the shape of a microseismically quiet realm in the Aegean lithosphere at 20–40 km depth, suggesting a relation between active processes at this depth range and uplift. The peculiar properties of the lithosphere and the plate interface beneath Crete are tentatively attributed to extrusion of material from a subduction channel, driving differential uplift of the island by several kilometres since about 4 Ma.
C1-Esterase Inhibitor Protects Against Neointima Formation After Arterial Injury in Atherosclerosis-Prone Mice
Authors: Shagdarsuren Erdenechimeg , Bidzhekov Kiril , Djalali-Talab Yassin , Liehn Elisa A. , Hristov Mihail , Matthijsen Robert A. , Buurman Wim A. , Zernecke Alma , Weber Christian 
Published: December 2007

Background—Although activation of the complement system has been implicated in the progression of human atherosclerosis, its function during arterial remodeling after injury has not been investigated. Here, we examined the contribution of the complement cascade to neointima formation in apolipoprotein E–deficient mice using a C1-esterase inhibitor (C1-inhibitor).Methods and Results—Apolipoprotein E–deficient mice fed an atherogenic diet were subjected to wire-induced endothelial denudation of the carotid artery and treated with C1-inhibitor (Berinert; 15 IU IV) or vehicle perioperatively and subsequently every 2 days. The effectiveness of C1-inhibitor treatment was confirmed by measurement of plasma C1-inhibitor activity. A significant reduction in serum triglyceride levels was observed in C1-inhibitor–treated mice, whereas cholesterol levels did not differ. After 3 weeks, neointimal area was significantly reduced in C1-inhibitor–treated mice versus controls, whereas medial area was unaltered. This was associated with a significant decrease in neointimal and medial macrophage and CD3+T-cell content. Expression of C3 mRNA was significantly reduced in plaques of C1-inhibitor–treated mice 10 days after injury, as assessed by reverse-transcription polymerase chain reaction. The peak in serum C3 levels after injury was markedly downregulated by C1-inhibitor, as evidenced by ELISA. Immunohistochemistry revealed strong expression of C3 and C3c, which colocalized to plaque macrophages and was reduced in C1-inhibitor–treated mice. C1-inhibitor impaired monocyte arrest on activated endothelium and platelets under flow conditions in vitro and leukocyte recruitment to carotid arteries 1 day after injury in vivo.Conclusions—C1-inhibitor limits neointimal plaque formation and inflammation. This may involve blockade of complement activation, inhibition of leukocyte recruitment, and reduced triglyceride levels, thus providing a multimodal approach to treat arterial disease.
Jean Delville's La Mission de l'Art: Hegelian Echoes in fin-de-siècle Idealism
Authors: Cole Brendan 
Published: December 2007

AbstractJean Delville was not only a gifted painter, but also a prolific author, poet and polemicist. He is unique amongst his artistic contemporaries for having written extensively on the subject of Idealism in art. Idealist philosophy, as an intellectual influence, was fairly pervasive amongst contemporary non-realist authors, poets and painters; the core nineteenth-century influence in this regard was the writings of Arthur Schopenhauer. Delville, however, took a different path, particularly in his seminal book, La Mission de l'Art, and his various polemical essays on the subject, which reflect, rather, key ideas derived from the writings of the German Idealist, G.W.F. Hegel. Hegel's influence on late-nineteenth century non-realist art is understated in the literature. This paper analyses the main ideas of Delville's La Mission de l'Art in the context of Hegelian Idealism. It focuses on key areas of this tradition, specifically with regard to the nature of the Idea and the Ideal, the relation of the Ideal to the natural world, the relation between the Idea and the notion of Beauty and the special role of the artist in revealing the Idea in physical form.
From Lateness To Waning To Crisis: the Burden of the Later Middle Ages
Authors: Kaminsky Howard 
Published: December 2007

AbstractThe common view of the Late Middle Ages as a time of decay is due to the very lateness imposed on this period by the idea of a Middle Ages, especially in the form of the "Waning model" created by Johan Huizinga in The Waning of the Middle Ages. The consequent "crises" predicated of most late-medieval phenomena, including the whole period, appear under critical analysis either as phantoms or as moments of progressive development. This discredits both the Waning model and the "Middle Ages" out of which it proceeds; they can best be replaced by the scheme that posits an "Old Europe" from the eleventh century to the eighteenth. Here the Middle Ages vanish and the fourteenth and fifteenth centuries, redeemed from the curse of lateness, appear with the twelfth and thirteenth as Early Old Europe.
Philosophy and Its Place in the Space of Western Spirituality: An Apology
Authors: Toth Imre 
Published: December 2007

AbstractPhilosophy has never been and never will be a science. Nevertheless it is a body of knowledge, a field of autonomous being and the subject’s ontic foundation as knowledge of itself. This paper provides an analysis of the nature of philosophy as an autonomous form of Western spirit during its historical development. The dialectic between reason, knowledge and freedom is studied through multiple historical examples from the Antiquity to modern times.
The Reinvention of the Couple
Authors: Kristeva Julia 
Published: December 2007

AbstractThis paper traces back on a personal tone a provocative evocation of Jean-Paul Sartre and Simone de Beauvoir. The author considers existentialism as a laboratory of existence that influenced a generation's manner of living and writing and made one's existential desires into historical and political acts. Its most representative mode of expression, literature, was as an indicator of the presence of the private throughout the public world and time. In this view, de Beauvoir's presence is approached both from the perspective of her understanding of the female, and from the particular kind of couple she formed with Sartre.;
What do Jean-Paul Sartre and Simone de Beauvoir Have to Say to Us Today?
Authors: Noudelmann François 
Published: December 2007

AbstractSartre's thought and practice cannot be separated from the experience of the Second World War. Emerging from the war, Sartre formed the idea that the human comes forth out of the subhuman. This paper analyses aspects of Sartre's humanism from the point of view of his political commitment, and presents Sartre's work as an antidote to contemporary economic and scientific determinism. Sartre credit was always given to the growth of freedom in action out of the most unexpected subjectivization. He firmly supported the founding idea of democracy – the power of everyman – and projected the intellectual's mission into each of us once we try to rethink critically our actions in the light of human purposes.
Beyond a Division: Giulio Preti and the Dispute between Analytic and Continental Philosophy
Authors: Peruzzi Alberto 
Published: December 2007

AbstractThis paper discusses the positions of Italian philosopher Giulio Preti (1911-1972) in relation to the quarrel between Analytic and Continental philosophy. Preti?s thought appears as a systematic thought permitting to overcome, through his logical, epistemological and linguistic reflection, the divide between these two approaches. The different features of his philosophy are analyzed here in detail and compared to the main theoretical assumptions of Analytic and Continental philosophy.
Bridging Worlds and Languages
Authors: Cravetto Maria Letizia 
Published: December 2007

AbstractThe author summarizes here the main theme of the papers gathered in the second part of this issue. It describes the dual identities they deal with (linguistic identities,métissages, masked exiles and social intermingling) and places them in the context of an ongoing seminar work carried out at the Maison des sciences de l’homme in Paris.
Exiles Masked, Masks of Exile
Authors: Pérez Paule 
Published: December 2007

AbstractThis paper traces back the psychological effects of the ‘masked exile’ of a Jewish Tunisian family settled in France. The author provides a rich analysis of a sudden and permanent change of nationality, country, language, urban bustle and family environment, following the ‘tunisification of Tunisia’ launched by President Bourguiba at the end of the 1950s. A comparison with the situation of later migrant workers from the Maghreb countries is sketched in the second part of this paper.
Predicting gene ontology functions from protein's regional surface structures
Authors: Liu Zhi-Ping , Wu Ling-Yun , Wang Yong , Chen Luonan , Zhang Xiang-Sun 
Published: December 2007

Abstract

Background
Annotation of protein functions is an important task in the post-genomic era. Most early approaches for this task exploit only the sequence or global structure information. However, protein surfaces are believed to be crucial to protein functions because they are the main interfaces to facilitate biological interactions. Recently, several databases related to structural surfaces, such as pockets and cavities, have been constructed with a comprehensive library of identified surface structures. For example, CASTp provides identification and measurements of surface accessible pockets as well as interior inaccessible cavities.

Results
A novel method was proposed to predict the Gene Ontology (GO) functions of proteins from the pocket similarity network, which is constructed according to the structure similarities of pockets. The statistics of the networks were presented to explore the relationship between the similar pockets and GO functions of proteins. Cross-validation experiments were conducted to evaluate the performance of the proposed method. Results and codes are available at: http://zhangroup.aporc.org/bioinfo/PSN/.

Conclusion
The computational results demonstrate that the proposed method based on the pocket similarity network is effective and efficient for predicting GO functions of proteins in terms of both computational complexity and prediction accuracy. The proposed method revealed strong relationship between small surface patterns (or pockets) and GO functions, which can be further used to identify active sites or functional motifs. The high quality performance of the prediction method together with the statistics also indicates that pockets play essential roles in biological interactions or the GO functions. Moreover, in addition to pockets, the proposed network framework can also be used for adopting other protein spatial surface patterns to predict the protein functions.
CD209 in inflammatory bowel disease: a case-control study in the Spanish population
Authors: Núñez Concepción , Oliver Javier , Mendoza Juan Luis , Gómez-García María , Taxonera Carlos , Gómez Luis M , López-Nevot Miguel A , de la Concha Emilio G , Urcelay Elena , Martínez Alfonso , Martín Javier 
Published: December 2007

Abstract

Background
The etiology of Ulcerative Colitis (UC) and Crohn's Disease (CD), considered together as Inflammatory Bowel Diseases (IBD), involves environmental and genetic factors. Although some genes are already known, the genetics underlying these diseases is complex and new candidates are continuously emerging. The CD209 gene is located in a region linked previously to IBD and a CD209 functional polymorphism (rs4804803) has been associated to other inflammatory conditions. Our aim was to study the potential involvement of this CD209 variant in IBD susceptibility.

Methods
We performed a case-control study with 515 CD patients, 497 UC patients and 731 healthy controls, all of them white Spaniards. Samples were typed for the CD209 single nucleotide polymorphism (SNP) rs4804803 by TaqMan technology. Frequency comparisons were performed using χ2 tests.

Results
No association between CD209 and UC or CD was observed initially. However, stratification of UC patients by HLA-DR3 status, a strong protective allele, showed that carriage of the CD209_G allele could increase susceptibility in the subgroup of HLA-DR3-positive individuals (p = 0.03 OR = 1.77 95% CI 1.04–3.02, vs. controls).

Conclusion
A functional variant in the CD209 gene, rs4804803, does not seem to be influencing Crohn's disease susceptibility. However, it could be involved in the etiology or pathology of Ulcerative Colitis in HLA-DR3-positive individuals but further studies are necessary.