bluuebunny/crossref_metadata_2025_split huggingface dataset:
Langzeit‐HCG‐Stimulation bei azyklischen Stuten
Authors: Holzmann A. , Dickie M.B. , Dobretsberger M. , Arbeiter K. 
Published: October 2007

Inhalt:Azyklische Hafingerstuten (n = 4), erhielten während des saisonalen Anöstrus 2 mal täglich HCG (750 IE) i.m. verabreicht. Die Medikationsdauer war wirkungsbezogen (10 bis 20 Tage). Die Stimulation wurde nach erfolgter Ovulation oder bei Ausbleiben der Follikelreijiung und Eifreisetzung abgebrochen. Sexualaktive Stuten (n = 3) blieben ohne Medikation und dienten als Kontrolle. Die Befunderhebung an den Ovarien erfolgte ultrasonographisch. Jede Stute wurde 2 mal täglich auf eine halbe Stunde zur Protokollierung des Sexualverhaltens mit einem Hengst aufeine gemeinsame Koppel gebracht. Bei drei von vier Stuten entwickelte sich während der Behandlung an einem Eierstock ein Follikel. Ein Tier reagierte erst nach einer Prostaglandinmedikation auf die HCG‐Stimulation mit einer Follikelanbildung und Ovulation. Die präovulatorische Gröβe der Follikel schwankte zwischen 3,2 und 5,2 cm (= 4,3 cm). Die Deckbereitschaft der Stuten war kein sicherer Hinweis auf die Präsenz eines ovulationsgerechten Follikels. Zwei HCG‐stimulierte Stuten hatten Perioden der Duldung, die nicht mit den Ovarbefunden korrelierten. In beiden Fällen wurde die Kopulation über mehrere Tage (5 bzw. 7) ohne nachweisbaren Follikel gestattet. Die Langzeitstimulation mit HCG war in allen Fällen erfolgreich und lieβ keine negativen Auswirkungen erkennen. Alle im Versuch stehenden Stuten konzipierten und brachten gesunde Fohlen zur Welt. Contents: Long‐term HCG treatment for ovarien stimulation in mares during seasonal anoestrous Haflinger mares (n = 4) were treated with hCG (750 IU) twice a day during seasonal anoestrous. The length of the medical attention was due to the effect (10 and 20 days). The stimulation stopped as soon as ovulation occured or follicular development and ovulation failed to appear. Mares with active ovaries (n = 3) remained untreated and were used as control animals. The ovaries were checked upon by ultrasonographic monitoring. Furthermore breading behaviour was recorded by teasing each mare with a stallion twice a day for half an hour on a pasture. During treatment three of four mares developed follicles on their ovaries. After a singular prostaglandin injection the fourth mare also responded to the medication by growing an ovarien follicle. The preovulatory diameter ranged from 3,2 to 5,2 cm (x = 4,3 cm). Behavioural oestrous was not reliably linked to periovulatory follicles. Two of the stimulated mares showed periods of behavioural oestrous without corresponding ovarien condition. Both of them were mounted by the stallion for some days (5 and 7 days) without the slightest incidence of follicles. The long term hCG treatment was successfull in all four cases and no negative effects were obtained. All the mares included in this report conceived and delivered healthy foals.
Comparative Studies of Ovarian Steroids in Blood, and Specific Proteolytic Enzymes in the Cervical Mucus, in Four Sheep Breeds after Oestrus Synchronization (Progesterone and PMSG). 1. Breed Variation of Oestradiol‐17ß and Progesterone in Blood during Natural Oestrus, Synchronized Oestrus, and the First Oestrus after Synchronized Oestrus
Authors: Kouskoura Th , Kouimtzis S. , Alexaki E. , Smokovitis A. 
Published: October 2007

Contents The concentrations of oestradiol‐17β and progesterone in the blood were studied during natural oestrus, synchronized oestrus, and the first oestrus after synchronized oestrus in four sheep breeds (Friesland, Chios, Serres and Karagouniki). During natural oestrus, significant variations of oestradiol‐17β concentration were only seen in Karagouniki ewes; during synchronized oestrus, oestradiol‐17β concentration in the blood showed a gradual decrease in all breeds. However, during the first oestrus after synchronized oestrus, the concentration of oestradiol‐17β in the blood returned to normal in all but the Serres breed.The concentration of progesterone in the blood showed no variation during natural oestrus, but, during synchronized oestrus, significant variations of progesterone in the blood were seen in all but the Serres breed. During the first oestrus after the synchronized oestrus, the progesterone in the blood returned to the natural‐oestrus levels with, however, some differences among the breeds.Oestrous synchronization therefore disturbed the con‐centration of oestradiol‐17P and progesterone in the blood of the ewe in a varying way, depending on the breed.
Comparative Studies of Ovarian Steroids in Blood, and Specific Proteolytic Enzymes in the Cervical Mucus, in Four Sheep Breeds after Oestrus Synchronization (Progesterone and PMSG). 2. Breed Variation of PAA, PAI and PI in the Cervical Mucus during Natural Oestrus, Synchronized Oestrus, and the First Oestrus after Synchronized Oestrus
Authors: Kouskoura Th , Kokolis N. , Rekkas C. , Smokovitis A. 
Published: October 2007

Inhalt Vergleichende Untersuchungen ovarieller Steroide im Blut sowie spezifische proteolytische Enzyme im Zervikalmukus bei vier Schafrassen nach Östrussynchronisation (Progesteron und PMSG). 2. Rassebedingte Unterschiede für PAA, PAI und PI im Zervikalmukus während des normalen und des synchronisierten Östrus sowie des ersten Östrus nach der SynchronisationPlasminogen‐Aktivator‐Aktivität (PAA), Plasminogen‐Aktivator‐Inhibition (PAI) und Plasmin‐Inhibition (PI) wurden im Zervikalmukus von vier verschiedenen Schafrassen (Friesland, Chios, Serres, Karagouniki) während des normalen und synchronisierten Östrus sowie des ersten Östrus nach der Synchronisation untersucht.PAA‐Konzentrationen stiegen in der Mitte des normalen Östrus an. Dabei traten rassespezifische Unterschiede auf. Ebenfalls rasseabhängig war die Veränderung von PAA im Zervikalmukus bei synchronisierten Tieren. Diese Veränderung bestand auch im ersten Östrus nach der Synchronisation bei allen Rassen außer bei Friesland‐Schafen. Es traten beide Typen des des Plasminogen‐Aktivator (t‐PA und u‐PA) auf.Rasseabhängig stieg PAI zur Mitte und am Ende des normalen Östrus an. Östrus‐Synchronisation veränderte PAI. Diese Veränderung hielt auch während des auf die Synchronisation folgenden Östrus an.PI stieg zum Ende des natürlichen Östrus an, wobei einige Rasseunterschiede beobachtet wurden. Im synchronisierten Östrus veränderten sich die PI‐Werte im Zervikalmukus. Außer bei Friesland‐Schafen hielt diese Veränderung des PI während des ersten Zyklus nach der Synchronisation an.Die Blutkonzentrationen von Östradiol‐17ßübten im begrenzten Maße bei einigen Rassen einen positiven Effekt auf PAA bzw. PAI und einen negativen Effekt auf PI im Zervikalmukus aus.
Hormonprofile von Färsen im frühen Östrus bei Superovulationseinleitung nach Eliminierung des dominanten Follikels
Authors: Stüwe S. , Lange W. , Rommel P. , Krause S. , Münnich A. 
Published: October 2007

Inhalt Ziel dieser Untersuchung war die Darstellung endokriner Abläufe nach Eliminierung eines dominanten Follikels vor der Superovulationsbehandlung im frühen östrischen Regime. Der Eliminierung des dominanten Follikels folgten keine Komplikationen und Ovarschädigungen. Die Ausschaltung des dominanten Follikels als Inhibinquelle führte zu einer Verstärkung der exogenen Gonadotropinstimulation durch eine erhöhte endogene FSH‐Freisetzung und löste Hyperstimulationseffekte aus. Basale P4‐Konzentrationen während der Follikelanbildung verursachten vermutlich Störungen der Follikel‐ und Oozytenreifung. Gegenüber konventionellen Regimen konnte die Anzahl (2,4 transfertaugliche Embryonen/Donor, n = 4) und die Qualität der Embryonen nicht gesteigert werden, die Variabilität der Embryonenausbeute blieb erhalten.Hormonal profiles of heifers in early estrous at initiation of a superovulatory treatment after the elimination of the dominant follicle
Non‐Infectious Factors in Sow's Abortion
Authors: Fekete S 
Published: October 2007

AbstractAutors, summarized possible causes of mamalian abortion with special emphasis to the pig. Besides the feed and enviromental pollutants like mycotoxins, polyclorinated biphenils, they describe the possible role of immunolical states, wich may contribute to the abortion. The importance of natural feed antinutrives are widely treated. Shown as a new approach to the topic, the possible part of algae and Legionella spp. is assumed.
Endocrine Aspects of Uterine Involution in the Cow
Authors: Kindahl H , Bekana M , Kask K , Königsson K , Gustafsson H , Odensvik K 
Published: October 2007

AbstractThe postpartum period (PP) (=puerperium) is characterized by involution of the uterus and recyclicity of the ovarian functions to prepare the animal for a new pregnancy period. The time required for the genital organs to become normalised is influenced by breed, management including feeding regimens and environmental factors. This period is also strongly influenced by periparturient diseases such as dystocia, paresis (puerperalis), mastitis, endometritis, etc. The period is also influenced by several hormonal changes. During the postpartum period in the cow, a massive release of PGF2α occurs concomitantly with the uterine involution. In cows with retained foetal membranes (RFM), a second pulsatile release of PGF2α is seen concomitant with the growth and final elimination of bacteria. A similar pattern is seen in cows with induced parturitions with e.g. dexamethasone, indicating the occurrence of RFM/endometritis as a consequence of the induction. The duration of these prostaglandin releases are negatively correlated to uterine involution in normal cows and positively correlated in cows with RFM/endometritis respectively. As long as the release is maintained, the cow is unable to ovulate and it therefore seems likely that PGF2α or other products in the arachidonic acid cascade can inhibit the ovarian activity. Onset of ovarian cyclicity influences to a high degree the uterine involution, however most common is that the first ovarian cycle is shorter than seen during the normal oestrous cycle. The uterine involution process can be enhanced by treatments with exogenous PGF2α‐ No effect on uterine involution in healthy cows, or a slight positive effect, is seen after treatment with prostaglandin synthesis inhibitors (e.g. flunixin meglumine). The aim of this presentation is to review some of the knowledge of the interactions between the uterus and ovaries during the postpartum period in cattle.
Effects of Endocrine Disrupting Compounds in Animal Feed on Reproductive Health in Farm Animals*Euroconference Wageningen, The Netherlands, 20–22nd November 1998
Authors: Boerjan M.L. , Fischer B. 
Published: October 2007

This Euroconference was a follow‐up to the Euroconference held in Halle, April 1997. The programme of the conference in Halle had an exploratory character with respect to accumulation of endocrine disrupting compounds (EDCs) in the environment and in animal tissues and their effects on animal physiology and reproduction. Many questions arose from the first Euroconference, such as: What are biologically meaningful levels of environmental contamination? Is there a risk for farm animals’ health and reproduction? What assays are available and which are the most appropriate to be used? These questions formed the basis for the programme of the second Euroconference held in Wageningen in November 1998.Taking these questions into consideration, the programme of the Wageningen Euroconference was divided into four main topics. In the first session an overview was given on sources and levels of EDCs in the environment. The second session addressed chemical nature and metabolism of EDCs including phytoestrogens. In the third session the effects of EDCs on ovarian function and embryo development were discussed and in the last session the advantages and disadvantages of different in vivo as well as in vitro assays were debated.
Changes in Lipid Classes and Fatty Acid Compositions in Purified Myelin of EAE Guinea Pig Brain
Authors: Iwaki Nobuhiro 
Published: October 2007

Abstract:Purified myelin fractions were prepared from brains of control and EAE sensitized guinea pigs on the 5th, 9th and 15th day after injection of antigen. Lipid classes were quantified and expressed as per cent of micromol contents of phospholipids and galactolipids, and fatty acid compositions each of them were analyzed.Cerebroside was markedly reduced with progress of the day, keeping Sulf/Osd ratio in normal constant (0.31–0.36). This was a characteristic finding in this study. Phosphatidyl ethanolamine, ethanolamine plasmalogen and sphingomyelin were also decreasing when compared among phospholipids whereas phosphatidyl choline was increasing. Fatty acid composition showed little change.Anionic lipids like sulfatide are said to play an important role in binding non‐ionic and zwitterionic lipids tightly to the myelin protein. From many reports on electron microscopic observations, it could be considered that the mode of insults to the myelin “lipid” would be rather secondary in demyelination process.The significance of the findings in this study and informations above mentioned were discussed, and a mechanism of demyelination was speculated. In brief, some factors might cause the ionic derangement in the basic amino group of myelin protein, the target of immune reaction, and anionic lipids might therefore be separated from it, being accompanied by such other lipids as cerebroside.
Studies Alkaline Phosphatase during Development Part II: Changes in alkaline phosphatase activity and isozyme patterns in the serum of healthy children and of children with various diseases
Authors: Mimura Tomohiko 
Published: October 2007

SummaryIn order to clarify the organ origins of high serum alkaline phosphatase in children during development and in children with various diseases, the serum alkaline phosphatase activity and isozyme patterns of children, umbilical cord blood and pregnant woman were investigated by the agar gel electrophoresis and heat stability test. In two infant autopsy cases, isozyme patterns were also investigated in several organs.1) Serum alkaline phosphatase activity of children was about 2.5 to 3 times as high as that of adults. In the group below 1 year of age and the group between 11 and 15 years of age, the levels were higher than in other groups.2) Alkaline phosphatase isozyme pattern in normal serum was showed as a single band (band III) around the α2‐globulin fraction in all groups.3) The alkaline phosphatase isozyme patterns in normal serum were divided into a pattern with non‐shifting peak after heat treatment at 56°c for 10 minutes and another with shifting peak to α1‐globulin side. In younger groups, the pattern with non‐shifting peak was more frequently seen and with growing the pattern with shifting peak increased. In adults, the peak shifted in all cases after heat treatment.4) The decreasing rate of alkaline phosphatase activity of normal serum by heat treatment was within the range of about 70–80% in each age group without remarkable differences. No calculation was possible in adult group, because the activity was markedly low.5) Serum alkaline phosphatase activity of pregnant women showed slightly higher than umbilical cord blood, about 3 times higher than in normal adults.The isozyme patterns were different between sera of pregnant women and umbilical cord blood.The decreasing rate of alkaline phosphatase activity after heat treatment (56°c for 10 minutes) was less in serum of pregnant women than in other sera, showing greater heat stability.6) Serum alkaline phosphatase was always high in diseases of liver and bone.Five bands of alkaline phosphatase activity were noted in the sera of normal subjects, pregnant women and children with various diseases.In liver diseases without marked obstruction and in bone diseases, the alkaline phosphatase isozyme pattern appeared in α2‐globulin band (band III). In liver diseases with marked obstruction, α1‐globulin band (band II originated from the liver) and β‐globulin band (band V probably from intestine) appeared. In one case, an Albumin‐α1 globulin band (band I) appeared.7) The alkaline phosphatase isozyme patterns in liver, bone, small intestine and kidney showed different electrophoretic migration rates indicating organ specificity.8) To sum up, serum alkaline phosphatase of the healthy children appeared to be originated from liver and bone. During childhood the alkaline phosphatase predominantly consists of bone origin, while in adults, major activity appeared to be hepatic origin.
Mucocutaneous lymph node syndrome presenting as acute cholecystitis
Authors: Tanaka Kazuhiko , Onouchi Zenshiro , Fushiki Shinji , Tomisawa Munehiko , Kusunoki Tomoichi 
Published: October 2007

AbstractMucocutaneous lymph node syndrome (MLNS) is not uncommon in Japan and it is well recognized that the dominant lesion is located in the coronary artery. We experienced recently a particular case which was diagnosed at first as acute cholecystitis, but a definite diagnosis of MLNS was later made from clinical manifestations and laboratory findings, especially ECG tracings, selective coronary angioram and selective celiac angiogram. We discussed the significant relationship between acute cholecystitis and MLNS.Mucocutaneous lymph node syndrome (MLNS) is an acute febrile and eruptive disorder described by Kawasaki1)2) for the first time in 1967. According to increasing reports, it has become gradually clear that the dominant lesion is located in the coronary artery and the symptoms result from the generalized vasculitis in small arteries and arterioles. Its etiology, however, remains unknown.The case, presented here was diagnosed at first as acute cholecystitis and treated with antibiotics, but a definite diagnosis of MLNS was later made by ECG and coronary angiograms.
Clinical Evaluation of the Pathogenesis of Neonatal Asphyxia
Authors: Tada Hiroshi 
Published: October 2007

AbstractThe perinatal mortality rate in Japan decreased from 16.8 per 1000 live‐births in 1964 to 4.5. in 1980, and the early neonatal mortality rate from 8.1 in 1964 to 1.1 in 1980. These decreases are mainly due to the improvement in prognosis of premature infants. The incidence of neonatal asphyxia in mature infants also decreased from 8.8% in 1967–68 to 5.1% in 1979–80. Fetal distress, breech delivery and Caesarean section were the major causes of neonatal asphyxia. Early detection of fetal distress and appropriate care decreased both the incidence of neonatal asphyxia and the neurological signs even in severely asphyxiated infants.
Neonatal Mass Screening of Hereditary Metabolic Diseases in S. Paulo‐Brasil
Authors: Schmidt Benjamin J. , Diament Aron J. , Krynski Stanislau , Kamei Maria E. , Rodrigues Maria M. C. , Takata Sumika 
Published: October 2007

AbstractThe authors report their experience in neonatal mass screening of hereditary metabolic disease in S. Paulo regarding hyperphenylalaninemia (by own programmation), others aminoacidophaties, congenital hypothyroidism, carbohydrates, mucopolysaccharides and heterozygotes for GM2‐gangliosidosis type I (Tay‐Sachs disease). The importance of the performing of such populational screening tests, even in developing countries is stressed.
Japanese Policies and Measures to Prevent Physical and Mental Disabilities
Authors: Fukuwatari Yasushi 
Published: October 2007

AbstractThe prevention of physical and mental disabilities is one of the major objectives of The Maternal and Child Health Services in Japan. The policies and measures to achieve these goals include the following:1. Health services (preventive and health promotive measures)2. Medical care services (curative measures)3. Arrangements to ensure the above mentioned activities4. Research, evaluation and future policy developmentThese should be integrated and coordinated so that their maximum effectiveness and efficiency can be brought into full play. The Ministry of Health and Welfare has been, and will continue to be, providing the highest quality services to all Japanese people in order to enrich their lives and prevent disabilities.
A Genetic Study of Hypohidrotic Ectodermal Dysplasia
Authors: Ohdo Shozo , Ikeda Takuya , Hayakawa Kunio 
Published: October 2007

AbstractThe heredity of hypohidrotic ectodermal dysplasia (HED) has been considered to be X‐linked recessive, autosomal recessive or autosomal dominant. In this report, a genetic analysis was carried out on a total of 57 patients with HED including 6 patients recently examined by the present authors and 51 patients reported in Japan before May, 1980.The morbidity varied depending on sexes, being significantly higher in men than in women (p < 0.001). Consanguinity was positive in 12.8% of the patients. The segregation ratio calculated, however, suggested that an autosomal recessive trait did not account for all the cases. The pedigree analysis and the segregation ratios revealed that HED was probably not autosomal dominant. It is finally pointed out that the heredity of all the patients with HED reported in Japan might be X‐linked recessive.
Tubuloreticular structures and parallel tubular arrays in the lymphocytes of children with aplastic anemia and acute febrile mucocutaneous lymph node syndrome: Electron microscopic observations
Authors: Bessho Fumio , Kobayashi Noboru 
Published: October 2007

AbstractTubuloreticular structure was found in 3 and 30% of the lymphoid cells from two consecutive cases of MCLS and in 10 and 15% of the lymphoid cells from two consecutive cases of aplastic anemia. Parallel tubular array was found in 8 and 24% of the lymphoid cells from the cases of MCLS and in 3% of the lymphoid cells from the cases of aplastic anemia. The possibility of the viral etiology of the both diseases was discussed.eases was discussed.
Angiospermic Changes of Coronary Aneurysms in Kawasaki Disease
Authors: Kawachi Kanji , Kitamura Soichiro , Oyama Choken , Koh Shigeo , Morita Ryuichi , Yamada Yoshiki , Kawashima Yasunaru 
Published: October 2007

AbstractThe fate of coronary aneurysms in Kawasaki disease or MCLS was examined by follow‐up studies on 9 patients with multiple bilateral aneurysms in the coronary arteries demonstrated by coronary arteriography. Their ages at the time if first examination ranged from 0.3 to 11 years (mean, 4.1 years). The mean interval between the onset of acute illness and the initial examination was 15.8 months, and the mean interval between the first and second examination was 17.9 months. Eight of the nine patients received anticoagulants between examinations. The second coronary arteriogram showed morphologic changes of the aneueysm from the time of the first examination: changes were seen in the right coronary artery area in 8 patients (89%) and in the left coronary artery area in 7 patients. These morphologuic changes seemed to be mainly secondary to thrombus formation, calcification, stenosis and/or obstruction of the aneuryms. Thus, coronary aneuryms in Kawasaki disease were transformed despite the use of anticoagulants.It is considered that multiple large coronary aneurysms will not healed or disappear, but are simply transformed as a result of their thrombosis and/or calcification.