bluuebunny/crossref_metadata_2025_split huggingface dataset:
Body Composition, Not Body Mass Index, Is Associated with Clinical Outcomes Following ACL Reconstruction
Authors: Buck Ashley N. , Moore Sam R. , Smith-Ryan Abbie E. , Schwartz Todd A. , Nelson Amanda E. , Davis-Wilson Hope , Blackburn J. Troy , Pietrosimone Brian 
Published: February 2025

ABSTRACT

Purpose
Determine the associations of body mass index (BMI) and body composition (lean and fat mass) with i) patient-reported outcomes, ii) quadriceps strength, and iii) physical performance in anterior cruciate ligament reconstruction (ACLR) patients.

Methods
Thirty-four individuals participated (56% female; 22 ± 4 years; % body fat: 22.9 ± 6.7%). Dual energy x-ray absorptiometry was used to measure percent lean (%LM) and fat (%FM) mass for the whole-body, and the whole-limb and thigh region of the ACLR limb. Knee Injury and Osteoarthritis Outcomes Score (KOOS) subscales were used to evaluate patient-reported outcomes. Isometric quadriceps strength (MVIC) was measured using an isokinetic dynamometer with the knee flexed at 90 degrees. Single-leg hop (SLH) distance was used to evaluate physical performance. Spearman rank correlations were used to separately evaluate the associations between BMI and body composition with KOOS, MVIC, and SLH.

Results
BMI was not significantly associated with KOOS, MVIC, or SLH (p > 0.05). Greater whole-body %LM associated with greater MVIC and SLH, while greater whole-body %FM associated with worse KOOS ADL, MVIC, and SLH (p < 0.05). Greater whole-limb %LM associated with greater MVIC, while greater whole-limb %FM associated with worse KOOS Symptoms, Pain, QoL, and MVIC (p < 0.05). Greater thigh %LM associated with better KOOS Symptoms and MVIC, and greater thigh %FM associated with worse KOOS Symptoms, Pain, QoL, and MVIC (p < 0.05).

Conclusions
Body composition characteristics of higher %LM and lower %FM associated with better clinical outcomes in ACLR patients of normal BMI status, thereby elucidating a potential modifiable target to mitigate poor ACLR-related outcomes. Future research should further evaluate mechanistic links between body composition and ACLR-related outcomes to inform clinical practice and rehabilitation frameworks.
Enabling Conversations About Privilege and Discrimination in Engineering Classrooms Through an Inequitable Decision-Making Activity
Authors: Nock Destenie 
Published: February 2025

Having conversations in the classroom about privilege, discrimination, prejudice, and how these issues impact decision making can be difficult. This article presents an activity designed to simulate voter and voice suppression in the classroom. The activity, titled “The Energy Table Who Didn’t Get a Seat,” started by asking students to use concepts from class to decide where to invest money to mitigate the effects of a winter storm on vulnerable communities. Then, the instructor simulated voice suppression, discrimination, macroaggressions, and prejudice in class by excluding certain groups from being able to submit their proposals for consideration. Throughout the class, students were given opportunities to advocate for themselves, yet they rarely did. At the beginning of the activity, students voted for which of their classmates’ proposals they believed was the best. However, by the end of the voter and voice suppression activity, 24%–46% of the students abstained from voting, highlighting the frustration they felt during the simulation. The class concluded with a discussion about how biases impact decision making. After the instructor revealed that the discrimination was part of a simulation, many expressed shock and surprise that they had not advocated for themselves during the activity. Funding: This work was supported by the National Science Foundation [Grants 2121730 and 2315029], the Wimmer Faculty Fellowship from Carnegie Mellon University, and the Division of Civil, Mechanical and Manufacturing Innovation [Grant 2053856]. Supplemental Material: The online appendix is available at https://doi.org/10.1287/ited.2023.0053 .
Antisocial Responses to the “Coal to Gas” Regulation: An Unintended Consequence of a Residential Energy Policy
Authors: Cao Jing , Liu Tracy Xiao , Ma Rong , Sun Ang 
Published: February 2025

Policies geared toward environmental and economic improvement could unexpectedly lead to negative consequences in other dimensions. Such cases raise a red flag to economists and policymakers who aim to deliver comprehensive and sensible policy evaluations. This article investigates antisocial behaviors in response to the Clean Winter Heating Policy (CWHP), which seeks to improve outdoor air quality. Our results show that participating villagers are more likely to violate laws to burn agricultural waste and exhibit lower prosociality in incentivized dictator games and public goods games. We further explore treatment heterogeneities and find that two channels are likely to play a part. First, the CWHP was perceived as a negative income shock. Therefore, the villagers would want to reduce their expenditure on straw disposal and behave less generously in the incentivized games. Second, the CWHP could trigger discontent and directly affect social preference. Additional evidence suggests that the antisocial (less prosocial) responses could have been avoided by granting larger upfront subsidies. This paper was accepted by Axel Ockenfels, behavioral economics and decision analysis. Funding: J. Cao gratefully acknowledges financial support from the National Natural Science Foundation of China [Grants 72243007 and 72250064] and the Ministry of Science and Technology of the People’s Republic of China [Grant 2023YFE0112900]. T. X. Liu gratefully acknowledges financial support from the National Natural Science Foundation of China [Grants 72222005 and 72342032]. R. Ma gratefully acknowledges financial support from the National Natural Science Foundation of China [Grants 72134006 and 72304272]. A. Sun gratefully acknowledges financial support from the National Natural Science Foundation of China [Grant 72373157], Fundamental Research Funds for the Central Universities, and the Research Funds of Renmin University of China [Grant 22XNA003]. The authors are also thankful for the support from the Energy Foundation, China Southern Power Grid Co., Ltd., Research Center for Green Economy and Sustainable Development and Institute for Global Development of Tsinghua University, and the Harvard-China Project on Energy, Economy and Environment. Supplemental Material: The online appendix and data files are available at https://doi.org/10.1287/mnsc.2023.01459 .
KONSEP FLEKSIBILITAS DALAM GIG ECONOMY DAN PENGARUHNYA PADA KINERJA PERUSAHAAN JASA: LITERATURE REVIEW
Authors: Tarigas Nopia 
Published: February 2025

Gig Ekonomi merupakan fenomena dalam bidang pekerjaan baru yang muncul akibat dorongan tren digitalisasi. Orang yang melakukan pekerjaan berbasis Gig Ekonomi disebut sebagai Gig Worker. Dalam persaingan yang terjadi di dunia bisnis, fleksibilitas memiliki peran yang penting bagi keberlangsungan kinerja bisnis. Kondisi permintaan pasar yang tidak tetap dan beragam menyebabkan perusahaan harus siap dengan respons fleksibel sebagai strategi operasi mereka. Penelitian ini bertujuan untuk merancang konsep fleksibilitas dalam dan pengaruhnya pada kinerja perusahaan jasa. Metodologi yang digunakan dalam penelitian ini adalah Systematic Literature Review (SLR). Hasil dari SLR menunjukkan bahwa fleksibilitas yang ada dalam Gig Worker berpotensi dalam meningkatkan kinerja perusahaan. Gig Ekonomi memiliki banyak peluang untuk Gig Worker, seperti lingkungan kerja yang fleksibel, bekerja sesuai dengan minat, dan dapat menjangkau pekerjaan secara global. Kata kunci: fleksibilitas; gig economy; gig worker; kinerja perusahaan
Eight weeks of resistance exercise improves mood state and intestinal permeability in healthy adults: A randomized controlled trial
Authors: Dow Emily , Hernandez Mario I. , Johnston Carol S. 
Published: February 2025

AbstractTo explore a potential link between resistance exercise and the gut‐brain axis, this study examined the impact of resistance exercise on intestinal permeability, as indicated by lipopolysaccharide binding protein (LBP), and mood state in healthy adults. Sedentary participants (n = 20; 39.5 ± 12.1 y; 27.4 ± 5.3 kg/m2) were randomly assigned to the resistance exercise (REX) or wait‐listed control (CON) groups. REX participants strength trained 3× weekly (advancing from 45%–55% to 70%–80% 1RM for 3–4 sets over 8 weeks). Strength testing, evaluation of mood states, and collection of fasting blood occurred at baseline and weeks 4 and 8. At baseline, LBP concentrations were inversely correlated to all strength measures (r range: −0.48 to −0.57; p < 0.05). The gain in total strength [(split squat left + right)/2 + bench press] was 45% higher for REX versus CON participants (p = 0.019), and serum LBP concentrations fell 16% for REX participants and rose 9% in CON participants (p = 0.014). Mood was significantly improved by resistance training versus control (but this improvement was not related to changes in LBP; r = −0.001). These findings support a role for resistance exercise in improving mood state and intestinal barrier function, but more research is warranted to further explore the effects of resistance training on the gut‐brain axis.
Inter‐individual variation in SpO2 during endurance exercise in hypoxia does not correlate with endocrine and angiogenic growth factor responses
Authors: Mori Hisashi , Hwang Hyejung , Goto Kazushige 
Published: February 2025

AbstractThe present study determined the relationship between inter‐individual variation in arterial O2 saturation (SpO2) and exercise‐induced endocrine and angiogenic growth factor responses under hypoxia. Sixteen healthy men completed two trials on separate days: 60 min of cycling at 65% of maximal oxygen uptake (VO2max) followed by a 60‐min rest period, under either normoxia (FiO2 = 20.9%, NOR) or hypoxia (FiO2 = 14.5%, HYP). Serum growth hormone (GH), cortisol, and vascular endothelial growth factor (VEGF) concentrations were determined before, immediately after, and at 60 min after exercise. SpO2 and heart rate were continuously measured during exercise. In the HYP trial, the average SpO2 during exercise varied by >10% among all participants (77.5%–88.2%). However, the ΔSpO2 (Δ = HYP–NOR) did not correlate significantly with exercise‐induced changes in serum ΔGH (r = 0.205, p = 0.446), Δcortisol (r = 0.059, p = 0.828), and ΔVEGF (r = −0.004, p = 0.989). Moreover, no significant correlations were observed between the absolute SpO2 value and exercise‐induced responses in these blood variables in the HYP trial. Inter‐individual variation in SpO2 did not modify exercise‐induced endocrine (GH, cortisol) or angiogenic growth factor (VEGF) responses to endurance exercise in hypoxia.
Impact of metal nanoparticles biosynthesized using camel milk on bacterial growth and copper removal from wastewater
Authors: Al-Mohaimeed Amal Mohamed , El-Tohamy Maha Farouk , Moubayed Nadine Mohamad Safouh 
Published: February 2025

Abstract
This study investigates the potential of zinc oxide (ZnO) and nickel oxide (NiO) nanoparticles (NPs), biosynthesized from camel milk, to combat bacterial resistance and enhance heavy metal removal from water. The antimicrobial efficacy against various pathogens, including Bacillus subtilis, Staphylococcus aureus, Escherichia coli, Methicillin-resistant Staphylococcus aureus, Pseudomonas aeruginosa, and Candida tropicalis were studied. Characterization of the NPs was conducted using UV-vis, Fourier transform infrared, X-ray diffraction, transmission electron microscope, and atomic force microscopy techniques. Results showed that ZnO NPs exhibited the highest antimicrobial activity, with an inhibition zone of 16 mm against Pseudomonas aeruginosa and 13 mm against Candida tropicalis, while NiO NPs displayed reduced activity against all selected microorganisms. Additionally, ZnO NPs demonstrated an impressive Cu(ii) ion removal rate of 96.76% at pH 8.4, with a contact time of 90 min, using 0.5 g·L−1 of adsorbent at an initial concentration of 200 mg·L−1. Adsorption kinetics followed the pseudo-second-order model, with isotherm data fitting the Langmuir model (Q
max = 100.0 mg·g−1, R
2 = 0.9905). Thermodynamic analysis indicated an exothermic process (∆H° = −4,127.4 J·mol−1) and spontaneous physical adsorption. Future research should focus on scaling up the biosynthesis of ZnO NPs for practical antimicrobial therapies and wastewater treatment technologies, alongside exploring their long-term environmental impact.
New ecological aspects of the pacarana (Dinomys branickii) in southeastern Peru
Authors: Pottie Sam , Basto Arianna , Whitworth Andrew , Beirne Christopher , Pillco Huarcaya Ruthmery , Forsyth Adrian 
Published: February 2025

Abstract
This study provides new insights into the behavioral ecology of Dinomys branickii based on long-term camera trap surveys conducted at three sites along an altitudinal gradient in southeastern Peru. Notably, we document the first known cases of geophagy in this species, which suggests a highly herbivorous diet. Moreover, in contrast to previous reports that described D. branickii as a group-living species, our data indicate that it is primarily solitary, with group formations likely limited to reproductive activities. Additionally, we confirm the species’ predominantly nocturnal and crepuscular activity patterns, with most activity occurring between 02:00 and 05:00 h. By calculating and comparing camera trap detection rates, used as an index of relative abundance (RAI), for D. branickii across different surveys, we highlight the species’ ecological rarity, evidenced by consistently low detection rates (0.163; 0.173 and 0.011 events per 1,000 trap-days) across diverse habitats and survey designs.
Diagnostic testing in the genetically complex age-related macular degeneration
Authors: Kiel Christina , Weber Bernhard H. F. 
Published: February 2025

Abstract
Age-related macular degeneration (AMD) is a leading cause of visual impairment with the risk of developing the disease influenced by a combination of genetic and environmental factors. With the recent expansion of treatment options, enhancing diagnostic accuracy and improving access to treatment are increasingly becoming the focus of interest. By using data from genome-wide association studies (GWAS) to generate polygenic risk scores (PRS), an assessment of an individual’s genetic risk for AMD is feasible. While the predictive accuracy of the AMD-PRS is most robust for individuals at very high genetic risk, genetic diagnostic testing is warranted due to the large number of affected individuals resulting from the high prevalence of AMD. Early genetic confirmation of AMD-related pathology can facilitate timely treatment initiation, potentially improving patient outcomes.
The crystal structure of the double salt dipyridin-1-ium bromide tribromide
Authors: Bo Wang , Hongxia Pan , Jun Chen , Yunlu Li , Lizhen Chen , Jianlong Wang 
Published: February 2025

Abstract
C10H12Br4N2, orthorhombic, Pbcn (no. 60), a = 13.3150(2) Å, b = 13.8478(2) Å, c = 15.7803(2) Å, V = 2909.63(7) Å3, Z = 8, Rgt
(F) = 0.0302, wRref
(F
2) = 0.0948, T = 220 K.
Aquinas on Beauty and Umberto Eco’s Interpretation
Authors: Di Ceglie Roberto 
Published: February 2025

Abstract
The Italian semiotician and novelist Umberto Eco (1932–2016) offered an insightful interpretation of Thomas Aquinas’ thought on beauty. Eco’s book, translated into English in 1988, is considered an authoritative source of reflection on the subject and has been widely cited by those who have focused on Aquinas’ aesthetics in recent decades. In this article, I first assess the depth and richness of Eco’s interpretation, including his critique of Aquinas’ view. I then reject this critique by arguing that Aquinas’ reflection on beauty is grounded in his theological interests, the connections between which and his aesthetic views are overlooked by Eco.
Investigating Confined Space Asphyxias: Plastic Bag Involvement and Gas Inhalation – A Case Series and Literature Review
Authors: Kaubrytė Sofija Saulė , Chmieliauskas Sigitas , Kažukauskė Giedrė , Laima Sigitas , Vasiljevaitė Diana , Stasiūnienė Jurgita 
Published: February 2025

Background: Asphyxia within confined spaces, particularly involving plastic bag suffocation and gas inhalation, presents complex forensic challenges. This study explores mechanisms, epidemiology, and forensic considerations of these fatalities, drawing from a comprehensive literature review and analysis of four clinical cases. Plastic bag asphyxia, exacerbated by oxygen depletion and carbon dioxide accumulation, induces rapid loss of consciousness and cardiorespiratory arrest. The method’s lethality is increased when combined with inert gases like helium, known for their rapid onset of hypoxia and painless nature. Recent research demonstrates a growing incidence of plastic bag suffocation as a method of suicide. The accessibility of suicide-related information on online platforms contributes to the dissemination of new methods, posing challenges for suicide prevention efforts. Forensic investigations often face obstacles in accurately determining the cause and manner of death, with nonspecific autopsy findings and scene manipulations complicating the diagnostic process.Materials and methods: A literature research was conducted across PubMed and Google Scholar databases, focusing on articles published in the last 5 years, applying keywords relevant to the topic under consideration and their combinations. 34 pertinent articles were selected, supplemented by data from the Lithuanian State Forensic Medicine Service, involving four clinical cases of confined space asphyxia. Autopsy findings, toxicological analyses, and contextual details were thoroughly examined to determine the mechanism and circumstances of death.Results: Plastic bag suffocation, often combined with inert gas inhalation, emerges as a common method in suicides. Demographic analyses reveal distinct patterns, with younger age groups demonstrating an increased tendency for gas inhalation suicides. The accessibility and perceived painlessness of helium contribute to its rising usage for suicide purposes. Forensic challenges include nonspecific autopsy findings, manipulations of death scenes, and difficulties in detecting inert gases postmortem. Enhanced surveillance and efforts to restrict access to these tools are crucial in preventing the spread of new suicide methods.Conclusions: The study highlights the multifaceted nature of asphyxiation deaths within confined spaces and the importance of proactive interventions in suicide prevention. Enhanced surveillance, tailored prevention strategies, and collaborative efforts are essential in addressing evolving suicide methods and reducing their impact.
Disease-specific signatures of circulating extracellular vesicles detected by the surface plasmon resonance imaging: a pilot study
Authors: Shibuta Tatsuki , Takada Yukichi , Nishinosono Shiori , Yasuda Seiko , Ono Yasuhiro , Hirooka Yoshitaka , Irikura Daisuke , Saito Kensuke , Umemura Tsukuru 
Published: February 2025

Aim: Cells in the human body release extracellular vesicles (EVs) into fluids, such as plasma, urine, and cerebrospinal fluid. EVs express tetraspanin family proteins (e.g., CD63, CD9, and CD81) and cell-specific antigens on their surface as common and specific markers, respectively. In this study, we hypothesized that the profile of blood cell-derived circulating EVs could reveal both common and specific pathophysiology in atherogenic diseases.
Methods: Using surface plasmon resonance imaging (SPRi), we analyzed EVs surface molecules and identified circulating EVs in healthy controls (n = 18), patients with type 2 diabetes mellitus (T2DM; n = 71), and those with hypertension (HT; n = 47).
Results: Patients with T2DM and HT exhibited distinct EV profiles: (i) CD9, CD110, CD20, activin receptor type-2A (AcvRIIA), Duffy antigen receptor for chemokine, and CD44 positive EVs were upregulated in T2DM; (ii) CD9, Maackia amurensis agglutinin lectin binding molecules (MBM), CD20, AcvRIIA, and CD44 positive EVs were upregulated in HT. By analyzing an appropriate set of three antigens or using dimensional reduction clustering, we were able to clearly differentiate between T2DM, HT, and control groups. In some patients, disease severity correlated with CD44 and CD20 in T2DM and MBM and AcvRIIA in HT.
Conclusion: Our findings demonstrate that profiling of circulating EVs via the SPRi method offers a novel approach for diagnosing and monitoring human diseases.
Analisis Respon dan Perilaku Masyarakat Terhadap Penggunaan Ecocapsitbag sebagai Solusi Pengganti Kantong Plastik Sekali Pakai untuk Mitigasi Solusi Plastik
Authors: Nindyasari Puspita Yulian , Ronggowulan Lintang , Muryani Chatarina 
Published: February 2025

<div><table cellspacing="0" cellpadding="0" align="left"><tbody><tr><td align="left" valign="top"><p><em>Penelitian ini bertujuan untuk mengkaji respon dan perilaku masyarakat terhadap penggunaan Ecocapsitbag sebagai solusi alternatif pengganti kantong plastik sekali pakai dalam upaya mengurangi polusi plastik. Penelitian ini menggunakan metode survei kualitatif yang melibatkan pembeli eoccapsitbag sebagai responden dengan berbagai latar belakang masyarakat. Survei ini mengukur tingkat kesadaran, penerimaan, dan penggunaan Ecocapsitbag dalam aktivitas sehari-hari. Hasil penelitian menunjukkan bahwa 81% responden sangat setuju bahwa polusi plastik merupakan masalah global yang serius dan membutuhkan solusi segera. Selain itu, 75% responden menyatakan kesediaan mereka untuk beralih menggunakan Ecocapsitbag daripada kantong plastik sekali pakai. Faktor-faktor yang mempengaruhi keputusan ini meliputi kesadaran lingkungan, pengetahuan produk, serta sikap dan perilaku masyarakat.</em><em> </em><em>Analisis lebih lanjut menunjukkan bahwa kampanye edukasi dan sosialisasi mengenai dampak negatif plastik dan manfaat Ecocapsitbag secara signifikan meningkatkan tingkat adopsi di kalangan masyarakat. Penelitian ini menyimpulkan bahwa Ecocapsitbag memiliki potensi besar sebagai pengganti kantong plastik sekali pakai, terutama dengan dukungan edukasi dan kebijakan yang tepat. Penggunaan Ecocapsitbag secara masif diharapkan dapat memberikan kontribusi yang signifikan </em><em>terhadap</em><em> upaya mengurangi polusi plastik, dengan demikian dapat menciptakan lingkungan yang lebih berkelanjutan dan dapat membatu mitigasi polusi plastik.</em><em></em></p><p><em>Kata Kunci : Ecocapsitbag, polusi plastik, perilaku masyarakat, mitigasi, kantong plastik sekali pakai</em></p></td></tr></tbody></table></div>