bluuebunny/crossref_metadata_2025_split huggingface dataset:
ChemInform Abstract: Composition Controlled Spin Polarization in Co1‐xFexS2 Alloys
Authors: Leighton C. , Manno M. , Cady A. , Freeland J. W. , Wang L. , Umemoto K. , Wentzcovitch R. M. , Chen T. Y. , Chien C. L. , Kuhns P. L. , et al. et al. 
Published: December 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Heterodimerization of Olefins: A Highly Promising Strategy for the Selective Synthesis of Functionalized Alkenes
Authors: Goossen Lukas J. , Rodriguez Nuria 
Published: December 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Photocycloaddition in Natural Product Synthesis
Authors: Iriondo‐Alberdi Jone , Greaney Michael F. 
Published: December 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Oxazaborolidines as Asymmetric Inducers for the Reduction of Ketones and Ketimines
Authors: Cho Byung Tae 
Published: December 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Cycloadditions and Other Additions to Alkenyl‐, Alkynyl‐ and Dienyl Boronic Esters
Authors: Carboni Bertrand , Carreaux Francois 
Published: December 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Chalcogenone C:E Compounds
Authors: Kuhn Norbert , Verani Gaetano 
Published: December 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Cucurbiturils as Molecular Containers Comparable to Cyclodextrins
Authors: Sliwa Wanda , Girek Tomasz 
Published: December 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Biocatalysis Applied to the Synthesis of Pheromones
Authors: Aleu J. , Bustillo A. J. , Hernandez‐Galan R. , Collado I. G. 
Published: December 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Asymmetric Syntheses of Pheromones
Authors: Mori Kenji 
Published: December 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Solid‐Phase Combinatorial Synthesis Based on Natural Products
Authors: Doi Takayuki , Takahashi Takashi 
Published: December 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Chemistry on the Interface of Natural Products and Combinatorial Chemistry
Authors: Boldi Armen M. , Dragoli Dean R. 
Published: December 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Frontiers in Nephrology: The Varied Faces of Natural Killer Cells in Transplantation — Contributions to Both Allograft Immunity and Tolerance
Authors: Beilke Joshua N. , Gill Ronald G. 
Published: December 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Intervention Strategies to Inhibit Protein Carbonylation by Lipoxidation‐Derived Reactive Carbonyls
Authors: Aldini Giancarlo , Dalle‐Donne Isabella , Maffei Facino Roberto , Milzani Aldo , Carini Marina 
Published: December 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Pathogenesis of Medulloblastoma and Current Treatment Outlook
Authors: Jozwiak Jaroslaw , Grajkowska Wieslawa , Wlodarski Pawel 
Published: December 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Mesoporous Materials for Drug Delivery
Authors: Vallet‐Regi Maria , Balas Francisco , Arcos Daniel 
Published: December 2007

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
GABAB receptor is a novel drug target for pancreatic cancer
Authors: Schuller Hildegard M. , Al‐Wadei Hussein A. N. , Majidi Mourad 
Published: December 2007

AbstractBACKGROUND.Pancreatic ductal adenocarcinoma (PDAC) is a leading cause of cancer death. Smoking, diabetes, and pancreatitis are risk factors. It has been shown that the growth of PDAC and pancreatic duct epithelial cells is regulated by beta‐adrenoreceptors (β‐ARs). The activity of β‐ARs in the central nervous system is counteracted by γ‐aminobutyric acid (GABA) via GABAB receptor‐mediated inhibition of adenylyl cyclase. The aim of the study was to investigate if GABABR inhibits β‐AR signaling in PDAC and pancreatic duct epithelial cells, thus blocking driving forces of cancer progression, such as cell proliferation and cell migration.METHODS.Intracellular cAMP was measured by immunoassays, DNA synthesis by BrdU incorporation assays, activation of ERK1/2 by ERK activation assays, and Western blots and metastatic potential by cell migration assays in the human PDAC cell lines PANC‐1 and BXPC‐3 and immortalized human pancreatic duct epithelial cells HPDE6‐C7. The expression of norepinephrine, PKARIIα, and GABA in PDAC microarrays was assessed by immunohistochemistry.RESULTS.Stimulation of the GABABR by GABA or baclofen inhibited isoproterenol‐induced cAMP signaling below base levels. ERK1/2 activity in response to isoproterenol was blocked by GABA, an effect enhanced by transient overexpression of the GABABR and abolished by GABABR knockdown. DNA synthesis and cell migration were stimulated by isoproterenol, responses blocked by GABA and baclofen. Norepinephrine and PKARIIα were overexpressed while GABA was underexpressed in human PDAC tissue arrays.CONCLUSIONS.The data suggest the stimulation of GABABR signaling as a novel target for the treatment and prevention of pancreatic cancer. Cancer 2008. © 2007 American Cancer Society.
Cloning and functional characterization of two key enzymes of glycosphingolipid biosynthesis in the amphibianXenopus laevis
Authors: Luque Melchor E. , Crespo Pilar M. , Mónaco María E. , Aybar Manuel J. , Daniotti José L. , Sánchez Sara S. 
Published: December 2007

AbstractGangliosides are a subfamily of complex glycosphingolipids (GSLs) with important roles in many biological processes. In this study, we report the cDNA cloning, functional characterization, and the spatial and temporal expression ofXlcgtandXlgd3 synthaseduringXenopus laevisdevelopment.Xlcgtwas expressed both maternally and zigotically persisting at least until stage 35. MaternalXlgd3 synthasemRNA could not be detected and showed a steady‐state expression from gastrula to late tailbud stage.Xlcgtis mainly present in involuted paraxial mesoderm, neural folds, and their derivatives.Xlgd3 synthasetranscripts were detected in the dorsal blastoporal lip, in the presumptive neuroectoderm, and later in the head region, branchial arches, otic and optic primordia. We determined the effect of glycosphingolipid depletion with 1‐phenyl‐2‐palmitoyl‐3‐morpholino‐1‐propanol (PPMP) in mesodermal layer. PPMP‐injected embryos showed altered expression domains in the mesodermal markers. Our results suggest that GSL are involved in convergent‐extension movements during early development inXenopus. Developmental Dynamics 237:112–123, 2008. © 2007 Wiley‐Liss, Inc.
Transcription factor onecut3 regulates intrahepatic biliary development in zebrafish
Authors: Matthews Randolph P. , Lorent Kristin , Pack Michael 
Published: December 2007

AbstractMembers of the onecut family of transcription factors play important roles in the development of the liver and pancreas. We have shown previously that onecut1 (hnf6) is important during the terminal stages of intrahepatic biliary development in zebrafish. Here we report the characterization of a third zebrafish onecut gene, onecut3 (oc3), and assay its expression during development and its role in biliary duct formation using morpholino antisense oligonucleotide‐mediated knockdown. These experiments reveal an important role for oc3 during the earliest stages of zebrafish biliary development, and suggest that zebrafish oc3 is the functional ortholog of mammalian hnf6, a gene that directs biliary differentiation from bipotential progenitor cells. Consistent with this, zebrafish hnf6 expression was significantly reduced in oc3‐deficient larvae. Knockdown of hnf6 in wild‐type zebrafish larvae also significantly reduced oc3 expression, suggesting a complex interaction between onecut family member proteins during the latter stages of zebrafish biliary development. Developmental Dynamics 237:124–131, 2008. © 2007 Wiley‐Liss, Inc.
Developmental regulation of muscleblind‐like (MBNL) gene expression in the chicken embryo retina
Authors: Huang Hu , Wahlin Karl J. , McNally Minda , Irving Natasha D. , Adler Ruben 
Published: December 2007

AbstractMuscleblind‐like (MBNL) is a CCCH zinc finger‐containing RNA‐binding protein required for the development of both muscle and photoreceptors in Drosophila; it is conserved evolutionarily, and it is associated in humans with the muscular disease myotonic dystrophy. Its role in the development of vertebrate retinal cells, however, remains unknown. As an initial approach to its investigation, we have cloned three chick muscleblind genes, characterized their isoforms, and examined their expression patterns in the chick embryo retina. The relative levels of expression of the MBNL genes increased during embryonic development. In situ hybridization (ISH) showed that the three MBNL mRNAs had widespread patterns of expression at all the developmental stages examined. Of interest, the temporal and spatial patterns of protein expression, detected by immunocytochemistry with antibodies against MBNL1 and MBNL2, were much more restricted than those seen by ISH. At early stages (ED5–7), for example, MBNL1 and MBNL2 mRNAs were present throughout the retina, but immunoreactivity for the corresponding proteins was largely restricted to the periphery of the optic cup (presumptive iris/ciliary epithelium/ciliary margin zone). MBNL1 and MBNL2 immunoreactivity became detectable at the fundus at later stages, but was limited to a very small subset of the cells that had ISH signals for the cognate mRNAs (particularly ganglion cells and photoreceptors). Within photoreceptors, MBNL1 and MBNL2 immunoreactivity first appeared in their inner segments; MBNL2 remained there, but MBNL1 became subsequently localized to their synaptic terminals. These expression patterns are consistent with the possibility that MBNLs may regulate photoreceptor development in the chick retina, much as MBL does in Drosophila, and suggest that the expression of MBNL1 and MBNL2 may be regulated posttranscriptionally. Developmental Dynamics 237: 286–296, 2008. © 2007 Wiley‐Liss, Inc.
Voltage fluctuation compensator for Shinkansen
Authors: Uzuka Tetsuo , Ikedo Shouji , Ueda Keiji , Mochinaga Yoshifumi , Funahashi Sadao , Ide Koiti 
Published: December 2007

AbstractIn AC electric railways, three‐phase voltage is changed into the single‐phase circuit of two circuits with the Scott‐connected transformer. If unbalancing of the load between single‐phase circuits becomes large, voltage fluctuation becomes large on the three‐phase side. Railway static power conditioner (RPC) was developed for the purpose of controlling voltage fluctuation on the three‐phase side. An RPC is comprised of a pair of self‐commutated PWM inverters. These inverters connect the main phase and teaser feeding buses, coupled with a DC side capacitor such as a back‐to‐back (BTB) converter. In this way, the two self‐commutated inverters can act as a static var compensator (SVC) to compensate for the reactive power and as an active power accommodator from one feeding bus to another. 20 MVA/60 kV RPCs started commercial operation in 2002 at each two substations on the newly extended Tohoku Shinkansen for compensating voltage fluctuation on the three‐phase side caused by traction loads, absorbing harmonic current. The results of operational testing indicate that an RPC can accommodate single‐phase loads such as those of PWM‐controlled Shinkansen and thyristor phase‐controlled Shinkansen, and handle the exciting rush current of transformers, as well as compensate for harmonics successfully. © 2007 Wiley Periodicals, Inc. Electr Eng Jpn, 162(4): 25–34, 2007; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/eej.20397
Branching probabilities planning of stochastic network model using genetic algorithm supported by sensitivity analysis
Authors: Kurihara Kenzo , Nagai Manabu , Nishiuchi Nobuyuki , Masuda Kazuaki 
Published: December 2007

AbstractThis paper proposes a new method of planning the project durations that are modeled as stochastic networks such as GERT networks. Since stochastic networks have a variable time and a branching probability for each arrow, the total duration of the network is also modeled as a variable. In order to complete the project by the desired date with a certain confidence, the variable times or branching probabilities of the network should be designed appropriately. We will propose a planning method for branching probabilities to realize the desired project duration using GA and Monte Carlo simulation. © 2007 Wiley Periodicals, Inc. Electr Eng Jpn, 162(4): 43–53, 2008; Published online in Wiley InterScience (www.interscience. wiley.com). DOI 10.1002/eej.20582
Developing the Kharasch Reaction in Aqueous Media: Dinuclear Group 8 and 9 Catalysts Containing the Bridging Cage Ligand Tris(1,2‐dimethylhydrazino)diphosphane
Authors: Díaz‐Álvarez Alba E. , Crochet Pascale , Zablocka Maria , Duhayon Carine , Cadierno Victorio , Majoral Jean‐Pierre 
Published: December 2007

AbstractThe dinuclear complexes [{RuCl2(η6‐p‐cymene)}2(μ‐THDP)] (4) and [{MCl(η4‐cod)}2(μ‐THDP)] [M = Rh (5), Ir (6)], containing the bridging cage‐type ligand tris(1,2‐dimethylhydrazino)diphosphane (THDP), have been synthesized in high yields (89–95 %) by treatment of dimers [{RuCl(μ‐Cl)(η6‐p‐cymene)}2] (1) and [{M(μ‐Cl)(η4‐cod)}2] [M = Rh (2), Ir (3)] with one equivalent of THDP. The structure of the (η6‐arene)ruthenium(II) derivative 4 has been unequivocally confirmed by means of X‐ray diffraction methods. All these complexes have been found to be active catalysts for the atom‐transfer radical addition of bromotrichloromethane to olefins (Kharasch reaction) in heterogeneous aqueous media under mild conditions (room temp.).(© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2008)
Strength vs. Accessibility: Unraveling the Patterns of Self‐Recognition in a Conformationally Locked Amino Alcohol
Authors: Mehta Goverdhan , Sen Saikat , Guru Row Tayur N. , Chopra Deepak , Chattopadhyay Sayani 
Published: December 2007

AbstractUnlike the self‐assembly of aminols studied till date, that of the conformationally locked, trans‐amino alcohol under study is unique in having the amino protons serving as mere spectators in the crystal packing. The principal non‐covalent interactions, holding the molecules in the crystal lattice, are O–H···N hydrogen bonds, and the rarely encountered π‐π stacking interactions between the isolated double bonds. Experimental charge density analyses have been carried out on the amino alcohol not only to characterize the non‐covalent interactions existing in the supramolecular assembly in terms of the topological features of electron density at their bond critical points, but also to elucidate the apparent presence of the “spectator” amino hydrogen atoms beyond the criteria of mere geometry. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2008)
Evaluation of evidence for infection as a mode of action for induction of rat lymphoma
Authors: Caldwell Jane C. , Jinot Jennifer , DeVoney Danielle , Gift Jeff S. 
Published: December 2007

AbstractThe European Food Safety Authority (EFSA) released a 2006 report questioning the relationship of aspartame exposure with increased incidence of lymphomas/leukemias in a European Ramazzini Foundation (ERF) rat study. The EFSA report suggested that the lymphoma/leukemia findings were most likely explained by infection in the rat colony. The ERF has also conducted the only available long‐term oral study of methyl tertiary‐butyl ether (MTBE). Thus, using the EFSA report as support, some have now raised questions about the human relevance of MTBE‐associated hemolymphoreticular tumors reported by the ERF in female rats as well as whether their incidence was elevated above background levels. In this report, we discuss the hypothesized mode of action (MOA) of infection‐induced lymphoma and its relevance to MTBE‐associated lymphomas. We address the relationship of rat strain and study duration to lymphoma susceptibility and review evidence of low background rates of this tumor in control animals at the ERF, similar survival rates for female rats at the ERF and National Toxicology Program (NTP), and chemical‐ and gender‐specificity of tumor induction for this type of tumor in studies at the ERF. We find that the background incidence of hemolymphoreticular tumors in female rats in the MTBE study is consistent with contemporaneous studies at the ERF and that there is an exposure‐related effect, which is unlikely to be due to infections. We examine more recent tumor classification schemes for lymphomas, which support the combination of lymphoblastic leukemias and lymphomas reported by Belpoggi et al. ([1995] Toxicol Ind Health 11:119–149; [1998] Eur J Oncol 3:201–206). Environ. Mol. Mutagen., 2008. Published 2007 Wiley‐Liss, Inc.
The numerical prediction of droplet deformation and break‐up using the Godunov marker‐particle projection scheme
Authors: Bierbrauer F. , Phillips T. N. 
Published: December 2007

AbstractThe problem of droplet deformation and break‐up is considered. A hybrid Eulerian–Lagrangian method is used in which the velocity and pressure are discretized on a fixed mesh and Lagrangian particles are used to implicitly track the interface between the two phases. The Navier–Stokes equations are solved using an approximate Godunov projection method, collectively called the Godunov marker‐particle projection scheme. The results show good qualitative agreement with previous research as well as demonstrating the efficacy of the method. Copyright © 2007 John Wiley & Sons, Ltd.
Global linear stability analysis of time‐averaged flows
Authors: Mittal Sanjay 
Published: December 2007

AbstractThe global linear stability analysis (LSA) of stationary/steady flows has been applied to various flows in the past and is fairly well understood. The LSA of time‐averaged flows is explored in this paper. It is shown that the LSA of time‐averaged flows can result in useful information regarding its stability. The method is applied to study flow past a cylinder at Reynolds number (Re) beyond the onset of vortex shedding. Compared with the direct numerical simulation, LSA of the Re=100 steady flow severely underpredicts the vortex shedding frequency. However, the LSA of the time‐averaged flow results in the correct value of the non‐dimensional frequency, St, of the associated instability. Copyright © 2007 John Wiley & Sons, Ltd.
Musashi1 RNA‐binding protein regulates oligodendrocyte lineage cell differentiation and survival
Authors: Dobson Nicole R. , Zhou Yong‐Xing , Flint Nicole C. , Armstrong Regina C. 
Published: December 2007

AbstractExpression of Musashi1 (Msi1), an evolutionarily conserved RNA‐binding protein, in neural stem cells of the subventricular zone in the postnatal and adult CNS indicates a potential role in the generation of oligodendrocytes. We now show Msi1 expression in a subset of oligodendrocyte progenitor (OP) cells in white matter areas temporally and spatially associated with oligodendrogenesis in the postnatal CNS. Msi1 function was evaluated by infection of OP cells with retroviral transduction of Msi1 or knockdown of endogenous Msi1. Retroviral expression of Msi1 significantly reduced the proportion of mature oligodendrocytes generated from OP cells in vitro and in vivo during myelination. Msi1 transduction also promoted OP survival, particularly under conditions of challenge from oxidative stress, while Msi1 siRNA knockdown resulted in dramatic OP cell death. Furthermore, in experimental demyelination Msi1 expression was increased among cells associated with lesions, including OP cells, indicating a potential role in the generation of remyelinating oligodendrocytes. © 2007 Wiley‐Liss, Inc.