bluuebunny/crossref_metadata_2025_split huggingface dataset:
Stereoscanning electron microscopy of argon laser excised laryngeal papilloma
Authors: Scully Peter A. , Stratton Clifford J. , Brophy John W. 
Published: October 2006

AbstractLaryngeal papillomas were removed from two patients with the argon laser and examined by transmission electron microscopy (TEM), scanning electron microscopy (SEM), and stereoscanning electron microscopy (SSEM). Two techniques, lipid‐carbohydrate retention for TEM specimens and sonication for SEM, were applied in studying the papillomas. Lipid‐carbohydrate retention results were in agreement with previous work in papilloma ultrastructure. The char interface was observed with the sonication technique. Peripheral to the laser impact site, four zones were observed: 1. coagulation necrosis, 2. contracted epithelial cells, 3. minimally damaged epithelial cells, and 4. morphologically undamaged epithelial cells. In Zone 2, cells were violently popped‐off as heat was conducted through the epithelium. The potential for spread of papillomas is discussed and suction of the vapor plume recommended when removing laryngeal papillomas with the argon laser.
Bioactive glass ceramic: A new material in tympanoplasty
Authors: Reck Ralf 
Published: October 2006

AbstractThe practicability of the bioactive glass ceramic Cernvitnl® in ear surgery was tested in animals. The histological findings are presented. Over the last 3 years implants of bioactive glass ceramic were used in humans. Prostheses for the total or partial reconstruction of the ossicular chain and the reconstruction of the bony wall of the outer ear canal were fashioned. We have conducted about 300 tympanoplasties and 60 total or partial reconstructions of the bony wall of the outer ear canal. The otoscopic and functional results were satisfactory.
Infiltrating lipoma of the sternocleidomastoid muscle
Authors: Mattel Stephen F. , Persky Mark S. 
Published: October 2006

AbstractInfiltrating lipomata are unusual benign tumors that have been rarely associated with the head and neck areas. We present the only known documented case of an infiltrating lipoma of the sternocleidomastoid muscle. The literature is reviewed and the characteristics of these lesions are discussed. The head and neck surgeon should include these interesting tumors in the differential diagnosis of head and neck masses and be aware that, because of a known propensity for recurrence, total surgical excision is the treatment of choice.
Wegener's granulomatosis
Authors: Mcdonald Thomas J. , Deremee Richard A. 
Published: October 2006

AbstractA review of 108 patients with Wegener's granulomatosis clarified the diverse clinical manifestations and disclosed some of the less well‐known areas of involvement. Because of the frequency of nasal involvement in Wegener's granulomatosis, the otolaryngologist plays an important role in the early diagnosis and treatment.
Complications after surgery for otosclerosis
Authors: Storrs Lloyd A. 
Published: October 2006

AbstractThis study was based on a detailed review of 503 cases of otosclerosis that were operated upon by me from 1961 to 1968. The vicissitududes of anesthesia, disequilibrium, dead ears and unexpected emotional abberations as well as legal and technical problems are discussed. Stapedectomy has been one of the most rewarding and technically challenging procedures that has come along in my career so far in medicine.
Complications of the treatment of malignant external otitis
Authors: Lucente Frank E. , Parisier Simon C. , Som Peter M. 
Published: October 2006

AbstractMalignant external otitis is an aggressive, potentially lethal infection of the temporal bone, the treatment of which is often fraught with complications. Among the reasons for these complications are the difficulty in assessing the extent of this disease, the uncertainty in determining the point at which treatment can be terminated, the toxic nature of the antibiotics used, and the technical difficulty of performing any surgery on the infected tissues. In those patients who receive inadequate initial therapy, the further extension of the disease itself represents a complication of treatment.
Complications after treatment of chronic maxillary sinus disease with caldwell‐luc procedure
Authors: Murray John P. 
Published: October 2006

AbstractThis short article deals with a review of the indications of the Caldwell‐Luc operation. It attempts to point out that the Caldwell‐Luc operation is not without complications and it is frequently associated with one or more of these. Various cases are sited illustrating this.A study examining 70 consecutive patients treated surgically by the author and 2 associates from 1972–1975 was done. One‐fourth of these were treated with intranasal procedures alone. The remainder were treated with Caldwell‐Luc, and most Caldwell‐Lucs were performed for intrasinus disease. The surgical technique is described followed by the indications for each. The postoperative problems are discussed and were found to be significant with recurrent sinusitis being most common. The remaining complications are likewise discussed.In summary, the Caldwell‐Luc operation has been employed for about 90 years for various indications. The indications expand with time; however, this seemingly benign operation is not without its incidence of complications and the morbidity is far greater than most of us often realize.
Complications after surgical management of the paralyzed larynx
Authors: Tucker Harvey M. 
Published: October 2006

AbstractPatients suffering from uni or bilateral laryngeal paralysis frequently require surgical management for best possible rehabilitation. As with any surgical procedure the potential for complications or less than optimal results exists. The Otolaryngologist‐Head and Neck Surgeon who wishes to provide best possible care for his patient must understand not only the indications for these surgical procedures, but also the complications that may be expected, so that every possible effort can be made to avoid or minimize them.
Tumors arising from the glandular structures of the external auditory canal
Authors: Hicks George W. 
Published: October 2006

AbstractNeoplasms in the external auditory canal (EAC) of ceruminous gland origin have been generally classified under the title of ceruminoma, which is inaccurate and misleading. There have emerged four distinct types of ceruminous gland tumors of the EAC. They are 1. ceruminous adenoma, 2. adenoid‐cystic carcinoma, 3. ceruminous adenocarcinoma, and 4. pleomorphic adenoma (mixed tumor). The natural course and clinical approach to these tumors can be determined by accurate histopathologic evaluation. This paper presents 10 cases of tumors of glandular origin in the EAC, 4 cases being ceruminous adenomas, 3 cases being adenoid‐cystic carcinomas, 2 cases being ceruminous adenocarcinoma, and 1 case of pleomorphic adenoma (mixed tumor). In reviewing these cases as well as those in the literature, a number of recommendations are suggested: 1. Identifying a tumor of the glandular structures of the EAC solely as a ceruminoma is no longer acceptable without accompanying histologic specificity. 2. Early wide excisional biopsy is imperative for diagnosis. 3. The signs and symptoms of the tumor do not always correlate with the histopathologic diagnosis and subsequent clinical behavior of these tumors. 4. Ceruminous adenoma and pleomorphic adenoma are benign tumors and are best treated only by wide local excision. 5. Adenoid‐cystic carcinoma and ceruminous gland adenocarcinoma are pernicious, malignant tumors which are best treated, in general, by an initial aggressive wide en bloc surgical resection or, if there is extension to the middle ear and temporal bone, by resection of the temporal bone and contiguous structures. 6. Postoperative irradiation has an essential role in managing these malignant tumors. 7. Five year survival rates for the malignant tumors do not reflect the biological behavior pattern of “late” local and distant recurrence and metastasis.
Surgery for nasal obstruction — Evaluation by rhinomanometry
Authors: Jalowayski Alfredo A. , Yuh Yih‐Shyh , Koziol James A. , Davidson Terence M. 
Published: October 2006

AbstractNasal obstruction is predominantly a subjective patient complaint. The physical examination of the nose for nasal obstruction is a subjective evaluation as well. While the history and physical examination are reasonable diagnostic indicators, an objective means of evaluation is needed. Rhinomanometry measures nasal obstruction objectively and reliably. Thirty‐six patients with nasal obstruction were evaluated by rhinomanometry before and after nasal surgery. The results are reported here. Rhinomanometry confirms the effectiveness of intranasal surgery. Using rhinomanometry, various techniques of intranasal surgery are evaluated, and several interesting observations are made.
Preoperative chemotherapy for hypopharyngeal carcinoma
Authors: Spaulding Monica B. , Kahn Anjum , Sundquist Nan , Lore John M. 
Published: October 2006

AbstractTwenty patients with advanced squamous cell carcinoma of the hypopharynx received two courses of chemotherapy with cisplatinum, vincristine and bleomycin before undergoing surgery. The chemotherapy was well tolerated, with minimal toxicity and no intra or postoperative complications attributable to it. The response to the chemotherapy was dramatic with all but 2 patients exhibiting a greater than 50% tumor shrinkage.Only 3 patients, all with positive surgical margins, received postoperative radiation therapy. Surgical salvage of recurrent lesions was performed on 2 patients who are now free of disease. With a median follow‐up of 20 months, 1 patient has died of recurrent disease, 3 have died of other causes, all others remain free of disease.
Prostatic and laryngeal malignancies: Common or uncommon multiple occurrence?
Authors: Wenig Barry L. , Abramson Allan L. 
Published: October 2006

AbstractThe presence of multiple primary malignancies involving the head and neck has been well documented. The majority of second primaries appear within the respiratory system. Few reports exist describing multiple primary malignancies involving the larynx and the prostate.This paper reports on four cases of primary laryngeal and prostatic neoplasms. Physical findings and laboratory work‐up necessary for diagnosis of these lesions are reviewed.The dilemma of the proper therapeutic course based on the histological grading and pathological staging is presented. Suggestions for treatment based on the prognosis of the disease that is present are offered.
Cervical tracheoesophageal fistula
Authors: Green Robert P. , Biller Hugh F. , Sicular Arthur , Wright Michael 
Published: October 2006

AbstractFour unusual cases of cervical tracheoesophageal fistula (TEF) are presented. The incidence, diagnosis and treatment of cervical TEF are discussed. Surgically, if the location is above the level of T2 a cervical approach may be utilized.The cases included a cervical “H” type TEF occurring in an adult. Congenital “H” type TEFs frequently occur in the neck. An adult presenting with a cervical “H” type TEF, having as an infant undergone repair of a thoracic TEF, is unique. Two layer closure of both trachea and esophagus with strap muscle interposition is preferred.The other cases include a TEF secondary to metastatic breast carcinoma, one associated with a stomal recurrence, and an acquired TEF following laryngectomy.Metastatic breast carcinoma resulting in a TEF is reported for the first time. Malignant TEF's are usually secondary to carcinoma of the esophagus, lung, or thyroid. Best palliation is achieved either by esophageal intubation, by colon bypass, or by gastric pull‐up with esophageal exclusion. Stomal recurrence with TEF following laryngectomy is treated with one‐stage resection and reconstruction with a pectoralis major myocutaneous flap and gastric pull‐up.A patient 5 years post‐laryngectomy illustrates an acquired non‐malignant cervical TEF, a category which includes fistulas due to trauma, tracheotomy, or endotracheal tubes, instrumentation, and inflammatory disease. Prompt surgical closure as in congenital cases is the treatment of choice although select cases require medical therapy.
Histopathology of the olfactory pathway due to ischemia
Authors: Nakashima Tadashi , Kimmelman Charles P. , Snow James B. 
Published: October 2006

AbstractVarious agents, such as trauma, viral infections and neoplasms cause olfactory dysfunction. However, little is understood concerning the role of ischemia. An experimental model of brain ischemia was developed in the Mongolian gerbil, and the olfactory pathway was studied. This animal was chosen because of its incomplete circle of Willis, since poor patency of the circle of Willis is not an uncommon finding in the aging human. Ischemia was induced by unilateral ligation of one common carotid artery or temporary occlusion of both common carotid arteries. Under both circumstances, ischemic changes occurred in the lateral olfactory tract, the olfactory ventricle, and the olfactory tubercle. Damage is more severe with bilateral temporary occlusion than unilateral ligation. The olfactory bulbs and neuroepithelium, however, are resistant to ischemia.
Pseudomonas rhinosinusitis
Authors: Fried Marvin P. , Kelly James H. , Strome Marshall 
Published: October 2006

AbstractAlthough rare in the otherwise healthy patient, pseudomonas rhinosinusitis is encountered most frequently in the immunocompromised host or severely traumatized patient. Intravenous antibiotic therapy in conjunction with aggressive surgical drainage is required. Two cases are documented that are typical of this philosophy. A third patient with isolated nasal involvement, because of multiple medical disabilities, was treated with local debridement and topical therapy alone and responded.
Histoplasmosis of the larynx
Authors: Donegan J. Oliver , Wood Michael D. 
Published: October 2006

AbstractGranulomatous diseases caused by infectious agents are being seen more frequently than before. Infection with Histoplasma capsulatum is one such granulomatous disease. This condition may have protean manifestations, with involvement of the larynx of particular interest to the Otolaryngologist. Histoplasmosis of the larynx may present difficult diagnostic problems and may closely mimic carcinoma. A case of histoplasmosis of the larynx treated at the University of Cincinnati Medical Center is presented and used to highlight the mode of presentation and the management of this particular disease. The clinical presentation of histoplasmosis is discussed with emphasis on involvement of the upper aerodigestive tract. The diagnostic tests of practical value are outlined. Amphotericin B is the treatment for this disease entity.
Review of cyanoacrylate tissue glues with emphasis on their otorhinolaryngological applications
Authors: Ronis Max L. , Harwich John D. , Fung Ramona , Dellavecchia Michael 
Published: October 2006

AbstractCynnoacrylates were first synthesized by Ardis in 1949. However, it was not until Coover in 1959 discovered their adhesive properties that an interest arose in using these substances in surgical procedures.Over the past two decades the use of cyanoacrylates has been varied and widespread among the surgical specialties. Methyl 2‐cyanoacrylate (Eastman 910 Monomer), Isobutyl‐cyanoacrylate (Bucrylate®), and 2‐cyano‐butyl‐acrylate (Histoacryl®) were the most widely used. Because of its tissue toxicity methyl 2‐cyanoacrylate was discarded. The consensus of various investigators was that the higher homologues, in particular Histoacryl® could be safely used in human applications.The authors thought it would be important to ascertain how the academic departments of Otolaryngology perceived the role of cyanoacrylates within their specialty. A questionnaire was distributed to 115 academic centers: 47% of the departments responded and, of those, 34% indicated a current working knowledge of the cyanoacrylates. This response confirmed a very active interest in these tissue adhesives despite a lack of F.D.A. approval.The otologic applications of these adhesives has been well documented, but the literature is devoid of studies using cyanoacrylates in other aspects of Otolaryngology. The authors feel that these adhesives (in particular Histoacryl®) have a role as an adjunctive technique in facial reconstructive and cosmetic surgery for autogenous cartilage grafting.A study using rabbits was designed to determine if Histoacryl® could be used safely to overcome the technical difficulties (graft migration during healing and cartilage fracture during suturing) often encountered when performing autogenous onlay cartilage grafting. On the left ear of each rabbit, a cartilage graft was harvested and reimplanted at a second site on the same ear by suturing the perichondrium of the graft to the perichondrium of the donor site. On the right ear the graft was secured to the donor site with Histoacryl.®The histological analysis of the rabbits' ears sacrificed at weekly intervals from 1 week to 1 month failed to demonstrate cartilage damage or tissue toxicity in the ears where Histoacryl® was used.In conclusion, the authors contend that a role exists for the use of Histoacryl® as an adjunctive technique in facial reconstructive and cosmetic surgery. The study will be continued to assess the long‐term results of using Histoacryl® for autogenous onlay cartilage grafting.
Mononuclear phagocyte function in head and neck cancer: Depression of murine macrophage accumulation by low molecular weight factors derived from head and neck carcinomas
Authors: Balm Fons J. M. , Von Blomberg‐Van Deflier B. Mary E. , Drexhage Hemmo A. , De Haan‐Meulman Meeny , Snow Gordon B. 
Published: October 2006

AbstractIn earlier experiments chemotactic responsiveness of peripheral blood monocytes obtained from patients with head and neck cancers was found to be markedly depressed. In an attempt to attribute this defect in migration to an influence excited by low molecular weight factors of less than 25,000 daltons, derived from the tumor, Amicon filtrates of head and neck cancer cells were administered sub‐cutaneously to C3H mice 24 hrs. before the intraperitoneal injection of concanavelin A. Subsequent macrophage accumulation into the peritoneal cavity was quantified. A clear inhibition of macrophage infiltration was found, particularly when filtrates of poorly differentiated tumors were used. Injection of filtrates from healthy oral mucosa were negative, whereas mouse mammary carcinoma filtrates strongly inhibited accumulation.
Rhabdomyosarcoma of the head and neck
Authors: Newman Anita N. , Rice Dale H. 
Published: October 2006

AbstractA retrospective review of all cases of rhabdomyosarcoma seen at UCLA was done. Survival prior to the advent of cyclic multidrug chemotherapy was compared to survival with this therapy. In the latter group, unlike other published series, survival was 100% better with gross total removal of disease as compared to biopsy only. All received at least 5000 rods.Fifteen percent presented with regional nodal metastases. However 75% of these also had intracranial extension and all died. An additional 19% developed late regional nodal metastases; 80% of these also developed systemic metastases and all died. Survival in the absence of nodal disease was 41%.
Osteosarcoma and chondrosarcoma of the head and neck
Authors: Vener Jerome , Rice Dale H. , Newman Anita N. 
Published: October 2006

AbstractOsteosarcomas and chondrosarcomas are rare malignant neoplasms in the head and neck. Eighteen cases seen at the UCLA Center for the Health Sciences are reviewed. Osteosarcomas of the maxilla tended to occur a decade later than those of the mandible or cranial bones. Several followed prior irradiation for retinoblastoma. Complete excision offers the only realistic chance for cure. Adjuvant therapy has little to offer these patients at this time.
Capsular significance in parotid tumor surgery: Reality and myths of lateral lobectomy
Authors: Donovan Donald T. , Conley John J. 
Published: October 2006

AbstractHistorically, parotid gland surgery has evolved from an operation of surgical enucleation to that of lateral lobectomy or total parotidectomy with facial nerve dissection. While the enucleation operation originally resulted in recurrence rates as high as 45% in some series, the technique of lateral lobectomy has resulted in recurrence rates of 2% in benign tumors. However, the currently recommended procedure of lateral lobectomy or total parotidectomy with facial nerve preservation for benign or low grade malignant tumors is not a pure en bloc resection in most cases, and in fact enucleation in part or total is often the reality of the operation. Tumor characterization, technical features, and operative findings of parotid gland surgery are examined in 100 consecutive cases. In over 60% of the cases, superficial or total parotidectomy with facial nerve preservation incorporated the principle of limited enucleation or capsular dissection at some point in the technique. The illusion that en bloc removal of parotid tumors with wide surgical margins is discredited. The reality of the procedure and the reasons for its success are examined.
Endoscopic photography of the ear, nose, and throat
Authors: Selkin Stuart G. 
Published: October 2006

AbstractThe ability to view and photograph the ears, nose, nasopharynx, hypopharynx, and larynx has been revolutionized by the advent of the flexible fiberoptic nasopharyngolaryngoscope. For the first time the otolaryngologist has a one‐instrument capability for examination and photodocumentation of the structures with which the specialty deals. This should not imply that the conventional means of examination should be relegated to museums, but rather that a new instrument has been added to the diagnostic armamentarium. The real visual images may be readily adapted for photography. The author will detail a straightforward and inexpensive method for obtaining high quality color transparencies, and color and sound video tapes.
Endolymphatic sac surgery in mondini's dysplasia: A report of 16 cases
Authors: Goin Donald W. , Rasband Rick W. , Mischke Robert E. , Weaver Marlin 
Published: October 2006

AbstractThis paper presents 12 patients (16 ears) with radiographic evidence of Mondini's dyplasia who underwent endolymphatic sac surgery. And additional 4 patients (7 ears) on whom surgery was not performed are included. Class I or II results were obtained in 81% of the ears. Pathophysiology, as it relates to the fluctuant nature of the hearing impairment, is discussed.
Cinegraphic observations of laryngeal function in parkinson's disease
Authors: Hanson David G. , Gerratt Bruce R. , Ward Paul H. 
Published: October 2006

AbstractThirty‐two unselected male patients with Parkinson's disease were examined by telescopic cinelaryngoscopy. Correlation of vocal abnormality and general neurologic symptoms with the laryngoscopic examination leads to the conclusion that the phonatory abnormalities noted in Parkinson's disease are related to rigidity in the phonatory posture of the larynx. The described dysfunctions correlated with the symmetry of trunk and limb rigidity in 100% of the patients.