bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Nonvolatile Memory and Neuromorphic Simulation of ReS2/h‐BN/Graphene Floating Gate Devices Under Photoelectrical Hybrid Modulations
Authors: Li Wei , Li Jiaying , Mu Tianhui , Li Jiayao , Sun Pengcheng , Dai Mingjian , Chen Yuhua , Yang Ruijing , Chen Zhao , Wang Yucheng , Wu Yupan , Wang Shaoxi 
Published: March 2024

AbstractThe floating gate devices, as a kind of nonvolatile memory, obtain great application potential in logic‐in‐memory chips. The 2D materials have been greatly studied due to atomically flat surfaces, higher carrier mobility, and excellent photoelectrical response. The 2D ReS2 flake is an excellent candidate for channel materials due to thickness‐independent direct bandgap and outstanding optoelectronic response. In this paper, the floating gate devices are prepared with the ReS2/h‐BN/Gr heterojunction. It obtains superior nonvolatile electrical memory characteristics, including a higher memory window ratio (81.82%), tiny writing/erasing voltage (±8 V/2 ms), long retention (>1000 s), and stable endurance (>1000 times) as well as multiple memory states. Meanwhile, electrical writing and optical erasing are achieved by applying electrical and optical pulses, and multilevel storage can easily be achieved by regulating light pulse parameters. Finally, due to the ideal long‐time potentiation/depression synaptic weights regulated by light pulses and electrical pulses, the convolutional neural network (CNN) constructed by ReS2/h‐BN/Gr floating gate devices can achieve image recognition with an accuracy of up to 98.15% for MNIST dataset and 91.24% for Fashion‐MNIST dataset. The research work adds a powerful option for 2D materials floating gate devices to apply to logic‐in‐memory chips and neuromorphic computing.
Increasing the sensitivity of Simoa via bead count reduction facilitates the quantification of pTau‐181 in dried plasma spots
Authors: Mohaupt Pablo , Vialaret Jérôme , Hirtz Christophe , Lehmann Sylvain 
Published: March 2024

AbstractIntroductionThe exclusion of affected populations from Alzheimer's disease (AD) clinical research limits our understanding of disease heterogeneity and its impact on clinical care. While micro sampling with dried plasma spots (DPS) can promote inclusivity by enabling sample collection in remote areas, current techniques lack the sensitivity required for the quantification of phosphorylated tau at Thr181 (pTau‐181) in DPS extracts.MethodsWe developed an assay for pTau‐181 with reduced bead count and improved bead read efficiency (BRE) using a prototype Simoa instrument. This novel assay's performance was evaluated against standard pTau‐181 assays on two Simoa platforms, and DPS extracts were tested for pTau‐181 quantification feasibility.ResultsThe novel assay quantifies pTau‐181 at concentrations up to 16x lower than traditional pTau‐181 assays on HD‐X and SR‐X platforms. DPS extracts tested with our low‐bead assay were quantified considerably above the lower limit of quantification (LLOQ), indicating the suitability of this assay for future DPS extract measurements.DiscussionImplementing DPS sampling and pTau‐181 quantification could increase participation from underrepresented groups in AD research. However, additional assay optimization and an in‐depth study of preanalytical sample stability are essential for the transition to clinical applicability.
Synthesis of star PMMA via ARGET ATRP towards application in acrylic bone cements
Authors: Tham Do Quang , Huynh Mai Duc , Dung Nguyen Thi Kim , Van Cong Do , Huyen Lai Thi , Linh Nguyen Thi Dieu , Thai Nguyen Thi , Son Nguyen Anh 
Published: March 2024

AbstractIn this study, we attempted to apply a four‐arm star poly(methyl methacrylate) (4sPMMA) as a prepolymer of acrylic bone cement. The 4sPMMA with viscosity average molecular weight of about 45 kDa was synthesized via Atom Transfer Radical Polymerization method using Activators Regenerated by Electron Transfer (ARGET ATRP). In practical use, the fine powder of precipitated 4sPMMA was changed to rigid beads followed by making sheet and pulverizing. Proton nuclear magnetic resonance (HNMR), Fourier transform infrared (FTIR) spectra of 4sPMMA beads indicated the star structure of 4sPMMA with bromide end groups (C‐Br). Scanning electron microscopy (SEM) image of 4sPMMA beads showed their random shapes with size in the range of 10‐100 μm, no traces of residual metal catalysts (Cu and Sn) were detected by Energy Dispersive X‐Ray (EDX) analysizer equipped with SEM instrument. Bone cement from 4sPMMA beads had been prepared manually and curing in rectangular and cylindrical molds. The setting characterization results showed that 4sPMMA bone cements exhibited lower maximum temperature (63.9 °C), lower setting temperature (45.6 °C), than those required in ISO 5833:2002. Other properties of 4sPMMA bone cement, such as bending strength, bending modulus and setting time met the requirements of above ISO standard.
Electrochemical performance of hard carbon anode in different carbonate‐based electrolytes
Authors: Kha Le Minh , Thanh Vo Duy , Van Hoang Nguyen , Thang Le Van , Phung Le My Loan 
Published: March 2024

AbstractThe electrolytes of 1 M NaFSI dissolved in various carbonate solvents containing EC, PC and/or DMC have been investigated to find out the most compatible electrolyte composition with hard carbon (HC) anode in Na‐ion batteries (NIBs). The physical properties including viscosity and conductivity were measured to correlate with the electrochemical behaviors of these electrolytes. The Na/HC half‐cell was used for testing the charge/discharge performance of prepared electrolytes at room temperature. This best medium for the solvation of NaFSI salt is the mixture of EC, PC and DMC with the ratio 3:1:1, respectively. Indeed, this electrolyte delivered a highest capacity of 335.6 mAh.g‐1, excellent capacity retention of 73.7 % for 100 cycles.
Dihydrostilbene glycosides and lignan from Camellia sasanqua
Authors: Cuc Nguyen Thi , Nhiem Nguyen Xuan , Tai Bui Huu , Van Kiem Phan , Thu Vu Kim 
Published: March 2024

AbstractThree dihydrostilbene glycosides, 3,5‐dihydroxydihydrostilbene 4′‐O‐β‐D‐glucopyranoside (1), 3,5‐dimethoxydihydrostilbene 4′‐O‐α‐L‐rhamnopyranosyl‐(1→6)‐β‐D‐glucopyranoside (2), 5,4′‐dihydroxydihydrostilbene 3‐O‐β‐D‐glucopyranoside (3), and one lignan, nudiposide (4) were isolated from the methanol extract of leaves of Camellia sasanqua Thunb. Their chemical structures were determined by using ESI‐MS and NMR spectra as well as in comparison with the reported data. Compounds 3 and 4 were reported from Camellia genus for the first time.
Isolation of lignans and neolignans from Pouzolzia sanguinea with their cytotoxic activity
Authors: Nhung Le Thi Hong , Anh Nguyen Thi Hoang , Tai Bui Huu , Van Kiem Phan 
Published: March 2024

AbstractOne lignan (7′S,8′R,8S)‐4,4′‐dihydroxy‐3,3′,5,5′‐tetramethoxy‐7′,9‐epoxylignan‐9′‐ol‐7‐one (1) together with four neolignans (7α,8α)‐dihydrodehydrodiconiferyl alcohol 9‐O‐β‐D‐glucopyranoside (2), (7α,8α)‐dihydrodehydro‐diconiferyl alcohol 9′‐O‐β‐D‐glucopyranoside (3), icariside E3 (4), and icariside E5 (5) were isolated from Pouzolzia sanguinea. Their chemical structures were elucidated by ESI‐MS, NMR spectra, as well as in comparison with the data reported in literature. At concentration of 30 μM, compounds 1‐5 exhibited weak cytotoxic activity with cell viability percentages ranging from 59.9±0.98 % to 84.2±0.98 % and from 77.7±0.81 % to 100.3±0.78 % on CAL27 (oral adenosquamous carcinoma cell) and MDA‐MB‐321 (breast cancer cell) cell lines, respectively.
Nitrate, nitrite, and lead contamination in leafy vegetables collected from local market sites of Go Vap district, Ho Chi Minh City
Authors: Thang Nguyen Quoc , Tho Nguyen Thi Mai , Phuong Nguyen Thi Kim 
Published: March 2024

AbstractLead, nitrate, and nitrite are among the major contaminants of vegetables. These concentrations appraise the quality characteristic of vegetables. Governments and regulators has control the level of nitrate, nitrite, and lead in vegetables to protect the human health. The present study was initiated to investigate the levels of these contaminants in five leafy vegetables in local market (Brassica juncea, Brassica integrifolia, Lactuca sativa, Ipomoea aquatica, and Nasturtium officinale). The vegetable species can be listed by decreasing nitrate content as follows: Lactuca sativa > Nasturtium officinale > Ipomoea aquatica > Brassica integrifolia > Brassica juncea. The nitrite content in leafy vegetables was significantly lower than nitrate content. Among observed vegetables, highest concentration of lead is in Ipomoea aquatica (0.200±0.011 mg/L), whereas lead content in Lactuca sativa and Nasturtium officinale were not detected. In addition, the Pb levels in the leafy vegetables were not correlated with nitrate concentration. Based on the results of our investigation, the approximate daily intake (DI) of NO3–, NO2– and Provisional Tolerable Weekly Intake (PTWI) of lead were assessed to human health in consuming the observed leafy vegetables.
Synthesis and Reactions of 1‐cyclopropyl‐1,3‐bis(trimethylsilyloxy)‐1,3‐buatdiene
Authors: Rahn Thomas , Langer Peter 
Published: March 2024

AbstractA cyclopropyl‐substituted 1,3‐bis(silyl enol ether) was prepared in two steps and subsequently employed in the cyclization with oxalyl chloride to give a cyclopropyl‐carbonyl substituted γ‐alkylidenebutenolide. The cyclization of the 1,3‐bis(silyl enol ether) with 1,3‐dielectrophiles afforded cyclopropyl‐carbonyl substituted phenols. The reactions proceeded with very good regioselectivity.
Combination of photothermia and magnetic hyperthermia properties of Fe3O4@Ag hybrid nanoparticles fabricated by seeded‐growth solvothermal reaction
Authors: Linh Nguyen Thi Ngoc , Tam Le The , Nguyet Ha Minh , Dung Ngo Thanh , Du Nguyen Hoa , Tam Le Thi Thanh , Nam Pham Hong , Vinh Nguyen Dinh , Vuong Nguyen Thien , Quang Ngo Dai , Lu Le Trong 
Published: March 2024

AbstractIn this work, the monodisperse Fe3O4@Ag core‐shell hybrid nanoparticles (NPs) with an average size of 16.0 nm have been successfully fabricated by the seeded‐growth method in the organic solvent. The influence of the molar ratios of AgNO3/OLA on the formation of hybrid NPs has been investigated in detail to find the optimal conditions for the synthesis of the desired Fe3O4@Ag hybrid NPs. The hydrophobic Fe3O4@Ag hybrid NPs were successfully transferred into the water using poly (maleic anhydride‐alt‐1‐octadecene) (PMAO). The PMAO coated Fe3O4@Ag nanoparticles were well dispersed and stable in water over a wide range of pH from 2 to 11 as well as reasonable electrolyte concentration. The Fe3O4@Ag magneto‐plasmonic design can efficiently combine magnetic hyperthermia into an effective bimodal thermo‐therapy.
Acetylcholinesterase sensor based on PANi/rGO film electrochemically grown on screen‐printed electrodes
Authors: Thanh Ly Cong , Nga Dau Thi Ngoc , Lam Nguyen Viet Bao , Do Chung Pham , Nhi Le Thi Thanh , Sinh Le Hoang , Thu Vu Thi , Lam Tran Dai 
Published: March 2024

AbstractIn this work, the polyaniline/reduced graphene oxide (PANi/rGO) bilayer was directly electrodeposited on carbon screen‐printed electrodes (SPE). Some details in growth of PANi/rGO bilayer were revealed from cyclic voltammograms and X‐ray photoelectron spectra. The growth of stacked rGO film at high compactness on the electrode surface is mainly accompanied with reduction of epoxy functional groups at basal planes of graphitic flakes. The as‐grown rGO layer with abundent hydroxyl functional groups at basal planes is preferable to attract intrinsic fibrillar‐like PANi polymer chains in protonated aqueous media. The as‐prepared PANi/rGO hybrid bilayer has shown good conductivity, high porosity, good adhesion to biomolecules, and fast electron transfer rate (increased by 3.8 times). Herein, PANi/rGO film has been further utilized to develop disposable acetylcholinesterase sensors able to detect acetylthiocholine (ATCh) with apparent Michaelis ‐ Menten constant of 0.728 mM. These sensors provide a very promising technical solution for in‐situ monitoring acetylthiocholine level in patients with neuro‐diseases and determination of neuro‐toxins such as sarin and pesticides.
Triterpenoids and steroids from the lichen Ramalina peruviana Arch
Authors: Chi Huynh Bui Linh , Linh Nguyen Thi Thuy , Hanh Le Hong , Linh Phan Hoang , Tuyen Pham Nguyen Kim , Phat Nguyen Tan , Tuyet Nguyen Thi Anh 
Published: March 2024

AbstractFive known triterpenes, β‐amyrone (1), isoarborinol acetate (2), hopane‐6α,22‐diol (3), hopane‐22‐ol (4), hopane‐6α,16β,22‐triol (5), along with two esgostane‐type sterols, 5α,8α‐esgosterol peroxide (6), brassicasterol (7) were isolated from the lichen Ramalina peruviana Ach. (Ramalinaceae). Their chemical structures were elucidated by spectroscopic data analysis and comparison with those reported in the literature. Except 2, this is the first time these compounds are reported in Ramalina genus.
Facile synthesis of Sn/SnOx@CMK‐3 composite for standout performance lithium‐ion batteries
Authors: Hang Le Thi Thu , Thuy Hoang Thi Bich , Dung Dang Trung 
Published: March 2024

AbstractTo develop new composites as advanced anode materials for lithium‐ion batteries, in the present study, we propose a facile technique to synthesize Sn/SnOx@CMK‐3 nanocomposites. The non‐carbonaceous components (two or three phases) present in the Sn‐based composites are probably tuned by changing the exposure duration in the air atmosphere. When being used as an anode for LIBs, the resulted multi‐phase composite, Sn/SnOx@CMK‐3 showed superior electrochemical performances to two‐phase composites such as Sn@CMK‐3 and SnO2@CMK‐3. Because of the synergy effect caused by Sn and SnOx, at a specific current of 100 mAg‐1 the Sn/SnOx@CMK‐3 electrode supplied a high discharge capacity of 702.9 mAhg‐1 after 100 cycles. The facile synthesis technique for Sn/SnOx@CMK‐3 can be considered as a role model for preparing other anode materials for LIBs.
Synthesis of new 3‐(hydroxymethyl)‐2‐phenyl‐2,3 dihydroquinolinone and in‐silico evaluation of COVID‐19 main protease inhibitor
Authors: Nepolraj Amaladoss , Shupeniuk Vasyl I , Sathiyaseelan Manisekar , Prakash Nagamuthu 
Published: March 2024

AbstractAn exclusive approach towards the synthesis of novel 3‐(hydroxymethyl)‐2‐phenyl‐2,3 dihydroquinolin‐4(1H)‐one and it's in‐silico evaluation as inhibitor of COVID‐19 main protease. The one‐pot synthesis of an established procedure Claisen ester condensation reaction was sodium hydride mediated with intramolecular cyclization with solvent free conditions. The structures of the synthesized compound were confirmed by IR, 1H,13C NMR, and EI‐MS spectral studies. Chemo‐informatics study showed that the compound obeyed the Lipinski's rule, PASS, Swiss ADME. Computational docking analysis was performed using PyRx, AutoDock Vina option based on scoring functions. In‐silico molecular docking study results demonstrated Greater binding energy and affinity to the active pocket the N3 binding site of the Coronavirus primary protease.
Iridoids and anthraquinones from the roots of Morinda officinalis
Authors: Anh Vu Thi Phuong , Van Minh Vo , Tuan Vo Chau , Van Khanh Nguyen , Dung Duong Thi , Nhiem Nguyen Xuan , Van Kiem Phan 
Published: March 2024

AbstractThree iridoids, asperulosidic acid (1), geniposidic acid (2), and galioside (3) and three anthraquinones, 2‐hydroxymethyl‐3‐hydroxyanthraquinone (4), rubiadin‐1‐methyl ether (5), and anthragallol‐2‐methyl ether (6) were isolated from the methanol extract of the Morinda officinalis leaves. Their chemical structures were elucidated by ESI‐MS, 1D‐ and 2D‐NMR spectra and comparison with the data reported in the literature. Galioside (3) was reported from Morinda genus for the first time.
Copper‐mediated annulation of 2‐aminoacetophenones and 2‐bromopyridines
Authors: Hai Pham Hoang , Nam Phan Thanh Son , Tung Nguyen Thanh 
Published: March 2024

AbstractA simple, practical method for synthesis of pyrido‐fused quinazolinones is herein developed. Reactions of 2’‐aminoacetophenones and 2‐bromopyridines proceeded in the presence of Cu(OAc)2 catalyst, NaOAc base, TEMPO co‐oxidant, and DMSO solvent. Simple functional groups were compatible with reaction conditions.
A theoretical investigation of the adsorption capacities of HCHO, HCOOH, CH3OH on M4 clusters (M = Au, Pd, Pt)
Authors: Linh Dao Thi Thao , Thuy Phan Thi , Ly Giang Thi Phuong , Cuong Ngo Tuan , Hue Nguyen Thi Minh 
Published: March 2024

AbstractThe absorptive capacity of formaldehyde, formic acid, and methanol on M4 clusters (M = Au, Pd, Pt) has been studied by the Density Functional Theory (DFT) using the B3LYP functional in conjunction with the aug‐cc‐pVTZ basis set for C, H, O atoms and the cc‐pVDZ‐PP basis set for transition metals. Our calculated results indicate that the absorption of three compounds onto Pt4 cluster is the most favorable among M4 clusters and the rank of absorption from most to least ability is Pt4 > Pd4 > Au4. This study is a contribution to the understanding of the interaction between HCHO, HCOOH, CH3OH and some precious metals and orientation for the reaction mechanism determination of these compound's decomposition catalyzed by the transition metal clusters.
Phytochemistry and anti‐inflammatory activity of iridoids from Dolichandrone spathacea collected in the mangrove forest of Phu Loc district, Thua Thien Hue province, Vietnam
Authors: Thao Tran Thi Phuong , Chi Nguyen Linh , Luu Nguyen Thi , Dung Nguyen Thi , Van Loc Tran , Van Tuan Nguyen , Hung Trieu Quy , Nhung Nguyen Thi Ai 
Published: March 2024

AbstractFrom the leaves and barks of Dolichandrone spathacea collected in the mangrove forest of Hue province, three iridoids {6‐O‐[(E)‐4‐methoxy cinnamoyl]catalpol (1), 6‐O‐[(E)‐3,4‐dimethoxy cinnamoyl]catalpol (2), nemoroside (3)} and three ursane‐type triterpenoids [ursolic acid (4), pomolic acid (5), uncaric acid (6)] were isolated and structurally elucidated. Besides, succrose octaacetate (7), daucosterol tetraacetate (8) and 1‐hentriacontanol (9) were identified from the fruits of this mangrove species. It is the first time compounds 6, 7, 9 were isolated from Dolichandrone spathacea. The main constituents of this plant, iridoids 1 and 2, were tested for the inhibition of IL‐6, TNF‐α factors and NO production. The anti‐inflammatory activity as well as the phytochemistry of the fruits of this species are reported for the first time.
Anti‐cancer docking investigations of Quinoxaline phenyl thiazolidinones
Authors: Kethireddy Shashikala , Ketha Swarupa , Eppakayala Laxminarayana , Chithaluri Sudhakar 
Published: March 2024

AbstractNew derivatives of quinoxaline phenyl thiazolidinones were synthesized and characterized using IR, H1 NMR and Mass spectroscopic techniques. Their molecular docking was performed using Auto Dock tools 4.2 software against epidermal growth factor receptor (EGFR) as a target and the images are being rendered using Schrodinger's maestro v9.5 vizualizer interface. The findings through docking studies are further useful in evaluating anti‐cancer activity of derivatives. Among all the derivatives, compound 6a has shown highest binding energy (‐9.95 Kcal/mol) and inhibition constant (50.91) towards the EGFR. The results of docking studies reported in this paper may provide very useful information to design the drugs for the therapeutic treatment of EGFR‐related cancers, such as lung, colorectal, pancreatic and head and neck cancers.
Structural and spectroscopic analysis of L‐Proline monomer and dimer by DFT approach
Authors: Borah Mukunda Madhab 
Published: March 2024

AbstractIn this work we have analyzed the Fourier Transform Infrared (FTIR), Raman and Surface Enhanced Raman Spectra (SERS) of L‐Proline. The molecule under consideration L‐Proline in monomer and dimer states were optimized using DFT/B3LYP and DFT/M06‐2X methods with 6‐31G (d,p) basis set. In order to correlate the experimental SERS spectra we have calculated the Raman spectra of L‐Proline monomer and dimer with silver (Ag) clusters using Density Functional Theory (DFT) with B3LYP functional and LANL2DZ basis set. The vibrational spectra were interpreted by using vibrational energy distribution analysis (VEDA) program and potential Energy Distribution (PED) analysis of the vibrational modes have been performed to have a clear picture of the fragments of different states of the molecule. The equilibrium molecular geometry, harmonic vibrational wavenumbers, Frontier molecular orbitals, Mulliken charges, energy parameters and various bonding features have also been computed.
Synthesis of a novel nano‐carrier system based on fucoidan conjugated to Pluronic for cell‐targeted delivery of anti‐cancer drugs
Authors: The Nguyen Ngoc 
Published: March 2024

AbstractNanocarrier systems for enhancing drug accumulation in cancer cells and minimizing side effects of anticancer drugs have been unceasingly developing throughout the years. In this study, we synthesized an advanced nanocarrier system polysaccharide fucoidan conjugated with pluronic P123 (Fud‐P123) utilized for the encapsulation of cisplatin (Cis) and its hydrate form (Cis‐OH). Cisplatin/Cis‐OH was loaded into the nanogel systems via the hydrophobic interaction of poly(propylene oxide) (PPO) fractions (P123) and the complexation between anionic groups (sulphate/carboxylate) present on the fucoidan flank with Cis‐OH. The chemical structure of the products was characterized by FTIR (Fourier‐Transform Infrared Spectroscopy), TEM (Transmission Electron Microscopy) and DLS (Differential Light Scattering) spectroscopy. The results show that Fud‐P123 nanogels are in spherical shape with the nanoparticle size distributed in the range of 40‐61 nm according to TEM, and 62.96 nm by DLS at 25°C. The loaded drug amount was determined by ICP‐OES (Inductively Coupled Plasma Optical Emission spectroscopy), and the percentage of Cis‐OH loaded in the nanogel was higher than cisplatin, accounting for about 22 %. This result confirms that Fud‐P123 nanogel is capable of carrying large amounts of cisplatin in hydrate form and thus can be applied as an ideal drug carrier formulation in cancer treatment.
A nonenzymatic uric acid sensor based on electrophoretically deposited Graphene/ITO electrode
Authors: Toan Tran Quoc , Dung Nguyen Quoc , Truong Mai Xuan , Van Hao Pham , Hien Trinh Ngoc , Van Dang Nguyen , Anh Le Phuoc , Hoa Nguyen Xuan , Thuy Pham Thi , Van Thanh Dang 
Published: March 2024

AbstractA nonenzymatic uric acid sensor is proposed based on an electrophoretically deposited Graphene/ITO electrode (EDG). The morphology and structure of the EDGs were characterized by scanning electron microscopy (SEM) and Raman spectroscopy. As a result, the EDGs electrode was successfully fabricated with a well‐adhered graphene film on the ITO substrate surface. The electrochemical properties of the EDG for uric acid were investigated in PBS buffer pH 7.4, using cyclic voltammetry (CV) studies. Quantification of uric acid using both cyclic scanning and differential addition polarization methods. As a result, the uric acid sensor has a linear range from 1 to 100 μM, sensitivity 318.4 (μAcm2mM‐1) from CV measurements. Moreover, by the differential pulse voltammetry (DPV), the sensor has a linear range from 1 to 50 μM, a sensitivity of 1242.7 (μAcm2 mM‐1), and the detection limit (LOD) of 0.6 μM (S/N = 3). The oxidation peak potential separation of uric acid, ascorbic, and dopamine at the EDG electrode showed that the uric sensor could eliminate interferences (ascorbic acid, dopamine) and be used to simultaneously determine uric acid, ascorbic acid, and dopamine.