bluuebunny/crossref_metadata_2025_split huggingface dataset:
Nucleic acid‐extracted torula yeast from the paper industry as a protein feed for ruminants: A comparison with soybean meal
Authors: Liu Chunyan , Asano Sanae , Sato Saeko , Murai Kae , Yabe Nanami , Kajikawa Hiroshi 
Published: April 2024

AbstractWe compared nucleic acid‐extracted torula yeast (NTY) with soybean meal (SBM) to evaluate NTY as a potential protein feed for ruminants in a metabolic trial using four castrated male goats. NTY was replaced isonitrogenously with SBM at a 25% crude protein (CP) level on a dry matter (DM) basis. NTY has 55% CP and 74% total digestive nutrients on DM. Absorbed N was lower on the NTY diet, but since the urinary N excretion was lower on the NTY diet, no significant between‐diet difference in retained N was observed. The efficiency of N utilization (retained N/absorbed N) was significantly higher on the NTY diet. The Lys and Met contents (presumed limiting amino acids for dairy cattle) were higher in NTY than SBM, which may be why N utilization efficiency was higher for the NTY diet. Ruminal ammonia‐N and blood serum N were lower on the NTY diet, suggesting that NTY has more rumen undegradable protein than SBM. There was no significant between‐diet difference in the visceral disorder indicators or antioxidant activities. Our results indicate that NTY is a safe protein feed with a high CP ratio and high‐quality amino acid profile for ruminants that is equivalent to SBM.
Different self‐damaging behaviours, similar motives? Testing measurement invariance of motives for nonsuicidal self‐injury, disordered eating and substance misuse
Authors: Robillard Christina L. , Merrin Gabriel J. , Legg Nicole K. , Ames Megan E. , Turner Brianna J. 
Published: April 2024

AbstractObjectivesTheory and research suggest that distinct self‐damaging behaviours (SDBs; e.g., nonsuicidal self‐injury [NSSI], restrictive eating, binge eating, drug misuse, alcohol misuse) share similar motives. However, few studies have used a common self‐report inventory to investigate the shared relevance and relative salience of motives for SDBs. Accordingly, the present study: (1) examined whether self‐report scales assessing intrapersonal motives (i.e., relieving negative emotions, enhancing positive emotions, punishing oneself) and interpersonal motives (i.e., bonding with others, conforming with others, communicating distress, communicating strength, reducing demands) have invariant factor structures across SDBs; and (2) compared the salience of these motives across SDBs.Methods1018 adults (54.6% men, Mage = 35.41 years) with a history of SDBs were allocated to the following groups: NSSI (n = 213), restrictive eating (n = 200), binge eating (n = 200), drug misuse (n = 200) or alcohol misuse (n = 205). Participants reported on their motives for engaging in their allocated SDB. Measurement invariance analyses compared the factor structures and latent means of the motive scales across SDBs.ResultsThe motive scales had comparable factor structures across SDBs. Intrapersonal motives were most strongly endorsed for NSSI and drug misuse. Interpersonal motives were most strongly endorsed for drug and alcohol misuse. All motives were least salient to restrictive eating.ConclusionsResults suggest that common motives underlie distinct SDBs and that they can be adequately assessed using a single self‐report inventory. However, certain motives are more relevant to some SDBs than others, with restrictive eating being the most motivationally distinct SDB. This knowledge can inform transdiagnostic models and interventions for SDBs.
Assessing quality of selection procedures: Lower bound of false positive rate as a function of inter‐rater reliability
Authors: Bartoš František , Martinková Patrícia 
Published: April 2024

AbstractInter‐rater reliability (IRR) is one of the commonly used tools for assessing the quality of ratings from multiple raters. However, applicant selection procedures based on ratings from multiple raters usually result in a binary outcome; the applicant is either selected or not. This final outcome is not considered in IRR, which instead focuses on the ratings of the individual subjects or objects. We outline the connection between the ratings' measurement model (used for IRR) and a binary classification framework. We develop a simple way of approximating the probability of correctly selecting the best applicants which allows us to compute error probabilities of the selection procedure (i.e., false positive and false negative rate) or their lower bounds. We draw connections between the IRR and the binary classification metrics, showing that binary classification metrics depend solely on the IRR coefficient and proportion of selected applicants. We assess the performance of the approximation in a simulation study and apply it in an example comparing the reliability of multiple grant peer review selection procedures. We also discuss other possible uses of the explored connections in other contexts, such as educational testing, psychological assessment, and health‐related measurement, and implement the computations in the R package IRR2FPR.
What drive financial inclusion gender gap in Cameroon? A Fairlie decomposition approach
Authors: Ndoya Hermann , Tsala Charly , Kamguia Brice 
Published: April 2024

AbstractBased on a Fairlie decomposition method, this paper analyzes the drivers of gender gaps in financial inclusion in Cameroon. We use Finscope 2017 data for Cameroon and assess six distinct financial inclusion variables grouped into two dimensions mainly, access to and use of financial products and services. Our results show that there is a gap in all indicators of access to and use of financial products and services in favor of men. The results also show that the largest contributor to the gender gap in access to financial products and services is income, with more than 50% of the contribution, whereas the largest contributor to the gender gap in the use of financial products and services is education with an average contribution of more than 35%. Based on the above findings, decision‐makers in Cameroon must conduct economic policies toward facilitating equitable access to education, by providing incentives to attract women to gain higher education.
Clonal expansion in normal tissues
Authors: Maeda Hirona , Kakiuchi Nobuyuki 
Published: April 2024

AbstractCancer originates from a single ancestral cell that acquires a driver mutation, which confers a growth or survival advantage, followed by the acquisition of additional driver mutations by descendant cells. Recently, it has become evident that somatic cell mutations accumulate in normal tissues with aging and exposure to environmental factors, such as alcohol, smoking, and UV rays, increases the mutation rate. Clones harboring driver mutations expand with age, leading to tissue remodeling. Lineage analysis of myeloproliferative neoplasms and der(1;16)‐positive breast cancer revealed that driver mutations were acquired early in our lives and that the development of cancer takes decades, unveiling the previously unknown early process of cancer development. Evidence that clonal hematopoiesis affects various diseases, including nonneoplastic diseases, highlights the potential role of the identification and functional analysis of mutated clones in unraveling unknown pathologies. In this review, we summarize the recent updates on clonal expansion in normal tissues and the natural history of cancer revealed through lineage analysis of noncancerous and cancerous tissues.
A Comprehensive Examination of Prediction‐Based Error as a Mechanism for Syntactic Development: Evidence From Syntactic Priming
Authors: Donnelly Seamus , Rowland Caroline , Chang Franklin , Kidd Evan 
Published: April 2024

AbstractPrediction‐based accounts of language acquisition have the potential to explain several different effects in child language acquisition and adult language processing. However, evidence regarding the developmental predictions of such accounts is mixed. Here, we consider several predictions of these accounts in two large‐scale developmental studies of syntactic priming of the English dative alternation. Study 1 was a cross‐sectional study (N = 140) of children aged 3−9 years, in which we found strong evidence of abstract priming and the lexical boost, but little evidence that either effect was moderated by age. We found weak evidence for a prime surprisal effect; however, exploratory analyses revealed a protracted developmental trajectory for verb‐structure biases, providing an explanation as for why prime surprisal effects are more elusive in developmental populations. In a longitudinal study (N = 102) of children in tightly controlled age bands at 42, 48, and 54 months, we found priming effects emerged on trials with verb overlap early but did not observe clear evidence of priming on trials without verb overlap until 54 months. There was no evidence of a prime surprisal effect at any time point and none of the effects were moderated by age. The results relating to the emergence of the abstract priming and lexical boost effects are consistent with prediction‐based models, while the absence of age‐related effects appears to reflect the structure‐specific challenges the dative presents to English‐acquiring children. Overall, our complex pattern of findings demonstrates the value of developmental data sets in testing psycholinguistic theory.
Deletion of Tgm2 suppresses BMP‐mediated hepatocyte‐to‐cholangiocyte metaplasia in ductular reaction
Authors: Chen Yaqing , Yan Yi , Li Yujing , Zhang Liang , Luo Tingting , Zhu Xinlong , Qin Dan , Chen Ning , Huang Wendong , Chen Xiangmei , Wang Liqiang , Zhu Xianmin , Zhang Lisheng 
Published: April 2024

AbstractTransglutaminase 2 (Tgm2) plays an essential role in hepatic repair following prolonged toxic injury. During cholestatic liver injury, the intrahepatic cholangiocytes undergo dynamic tissue expansion and remodelling, referred to as ductular reaction (DR), which is crucial for liver regeneration. However, the molecular mechanisms governing the dynamics of active cells in DR are still largely unclear. Here, we generated Tgm2‐knockout mice (Tgm2−/−) and Tgm2‐CreERT2‐Rosa26‐mTmG flox/flox (Tgm2CreERT2‐R26T/Gf/f) mice and performed a three‐dimensional (3D) collagen gel culture of mouse hepatocytes to demonstrate how Tgm2 signalling is involved in DR to remodel intrahepatic cholangiocytes. Our results showed that the deletion of Tgm2 adversely affected the functionality and maturity of the proliferative cholangiocytes in DR, thus leading to more severe cholestasis during DDC‐induced liver injury. Additionally, Tgm2 hepatocytes played a crucial role in the regulation of DR through metaplasia. We unveiled that Tgm2 regulated H3K4me3Q5ser via serotonin to promote BMP signalling activation to participate in DR. Besides, we revealed that the activation or inhibition of BMP signalling could promote or suppress the development and maturation of cholangiocytes in DDC‐induced DR. Furthermore, our 3D collagen gel culture assay indicated that Tgm2 was vital for the development of cholangiocytes in vitro. Our results uncovered a considerable role of BMP signalling in controlling metaplasia of Tgm2 hepatocytes in DR and revealed the phenotypic plasticity of mature hepatocytes.
Introduction to the Compositae of the North American Prairies
Authors: Hind Nicholas 
Published: April 2024

SummaryThe North American Prairie landscape at the Royal Botanic Gardens, Kew at Wakehurst Place, Ardingly, West Sussex, is discussed. The abundance of the Compositae in the North American Prairies is outlined, by tribe, and comments provided on a range of 105 interesting Compositae that could be considered in prairie plantings, for dry, moist and wet situations. The exclusion of a number of plants that are most unsuitable for prairie plantings is also covered, with whole tribes, such as the Cardueae and Anthemideae, excluded from potential planting schemes, and a limited selection made from the Lactuceae and Senecioneae. The Astereae, other than providing a large selection of potential prairie plants, is discussed more fully, especially with the break‐up of the core genus Aster. Both inside and outside of the prairie environment there have been many taxonomic changes, with name changes of concern to taxonomists and horticulturists alike. Shaw's list is revised, relevant to those he left in Aster, and some observations made on how the splitting of Aster is still an active area of research. The differing propagation methods, in general and for the Compositae in particular, are outlined, covering vegetative propagation methods, and seed harvesting, cleaning, and sowing preparation techniques outlined. A number of previously published plates from Curtis's Botanical Magazine are used to illustrate some of the tribes, and are supplemented by photographs of several species, mostly from the Heliantheae, in cultivation at the Royal Botanic Gardens, Kew. The supportive appendices cover: Appendix 1 – 105 suitable Compositae that can be considered for prairie plantings, each with an indication of tribe, common name/s, publication details of those previously illustrated in Curtis's Botanical Magazine (or in this issue), the plate number under which it was published, together with those republished in this issue, and photographs of a handful of others, together with an indication of the base colour/s of the flowering capitula of each, and Appendix 2 an updated list of the species left in Aster in Shaw's 2014 list following several subsequent transfers into other genera, and a different view of the taxonomy of some of the genera.
Projected climate‐driven shifts in coral distribution indicate tropicalisation of Southwestern Atlantic reefs
Authors: Martello Melina Ferreira , Bleuel Jessica , Pennino Maria Grazia , Longo Guilherme Ortigara 
Published: April 2024

AbstractAimPredicting and acting on the future of ecosystems requires understanding species distribution shifts due to climate change. We investigated which corals are more likely to shift their distribution in the Southwestern Atlantic under a warming scenario.LocationSouthwestern Atlantic (SWA; 1° N–28° S).MethodsWe used spatial distribution models with a Bayesian approach to predict the current and future (2050 and 2100) coral occurrence probabilities of 12 zooxanthellate corals and hydrocorals under an intermediate scenario of increasing greenhouse gas emissions (RCP6.0) projected by the Intergovernmental Panel on Climate Change (IPCC).ResultsWe found a decline in the occurrence probabilities of all 12 taxa within the tropics (1° N–20° S) and an increase towards subtropical sites (20–28° S) as early as 2050. The most significant declines are projected to occur between 9° S and 20° S, a region that currently hosts the richest reef complex in the South Atlantic, the Abrolhos bank. The imminent loss of suitable habitat in the tropics mostly threatens the Brazilian endemics and range restricted corals Mussismilia braziliensis and Mussismilia harttii, while more widely distributed taxa such as Siderastrea spp., Millepora spp. and Porites spp. are expected to expand their ranges southwards.Main ConclusionsThe projected declines in the tropical region are likely to reduce structural complexity causing biodiversity loss. The overall increase in occurrence probabilities in subtropical areas indicates tropicalisation of SWA reefs, which may benefit species already established in these areas and potentially enrich coral assemblages through the range expansion of taxa that currently do not occur in the region. These findings emphasise the need to support ecological corridors that could aid coral migration towards more suitable habitats under climate change.
Evaluation of quality and quantity of randomized controlled trials in hepatobiliary surgery: A scoping/mapping review
Authors: Majlesara Ali , Aminizadeh Ehsan , Ramouz Ali , Khajeh Elias , Shahrbaf Mohammadamin , Borges Filipe , Goncalves Gil , Carvalho Carlos , Golriz Mohammad , Mehrabi Arianeb 
Published: April 2024

AbstractAimTo evaluate the quantity and quality of randomized controlled trials (RCTs) in hepatobiliary surgery and for identifying gaps in current evidences.MethodsA systematic search was conducted in MEDLINE (via PubMed), Web of Science, and Cochrane Controlled Register of Trials (CENTRAL) for RCTs of hepatobiliary surgery published from inception until the end of 2023. The quality of each study was assessed using the Cochrane risk‐of‐bias (RoB) tool. The associations between risk of bias and the region and publication date were also assessed. Evidence mapping was performed to identify research gaps in the field.ResultsThe study included 1187 records. The number and proportion of published randomized controlled trials (RCTs) in hepatobiliary surgery increased over time, from 13 RCTs (.0005% of publications) in 1970–1979 to 201 RCTs (.003% of publications) in 2020–2023. There was a significant increase in the number of studies with a low risk of bias in RoB domains (p < .01). The proportion of RCTs with low risk of bias improved significantly after the introduction of CONSORT guidelines (p < .001). The evidence mapping revealed a significant research focus on major and minor hepatectomy and cholecystectomy. However, gaps were identified in liver cyst surgery and hepatobiliary vascular surgery. Additionally, there are gaps in the field of perioperative management and nutrition intervention.ConclusionThe quantity and quality of RCTs in hepatobiliary surgery have increased over time, but there is still room for improvement. We have identified gaps in current research that can be addressed in future studies.
Sex‐associated differences in cardiac ageing: Clinical aspects and molecular mechanisms
Authors: Calvo‐López Margarita , Ortega‐Paz Luis , Jimenez‐Trinidad Francisco Rafael , Brugaletta Salvatore , Sabaté Manel , Dantas Ana Paula 
Published: April 2024

AbstractDespite the extensive clinical and scientific advances in prevention, diagnostics and treatment, cardiovascular diseases (CVD) remain the leading cause of morbidity and mortality worldwide for people aged 65 and over. Of all ageing‐related diseases, CVD are responsible for almost one‐third of deaths in the elderly, being above all cancers combined. Age is an independent and unavoidable risk factor contributing to the impairment of heart and blood vessels. As the average age of the population in industrialized countries has doubled in the last century, and almost a fifth of the world's population is predicted to be over 65 in the next decade, we can assume that the burden of CVD will fall primarily on the elderly. Evidence from basic and clinical science has shown that sex significantly influences the onset and severity of CVD. In women, CVD usually develop later than in men and with atypical symptomatology. After menopause, however, the incidence and severity of CVD increase in women, reaching equality in both sexes. Although intrinsic sexual dimorphism in cardiovascular ageing may contribute to the sex differences in CVD progression, the molecular mechanisms associated with cardiovascular ageing and their clinical value are not known in detail. In this review, we discuss the scientific knowledge available, focusing on structural, hormonal, genetic/epigenetic and inflammatory pathways, seeking to transfer these findings to the cardiovascular clinic in terms of prevention, diagnosis, prognosis and management of these pathologies and proposing possible validation of target specifics.
Unveiling climatic niches for deeper insights into invasion potential and enhanced distribution models of freshwater fishes
Authors: Jan Arif , Giannico Guillermo , Arismendi Ivan , Flitcroft Rebecca 
Published: April 2024

AbstractIntroduced species may exhibit variations in their preferred climatic niches between their native and introduced ranges, which can have important implications for the transferability of distribution models. In the Himalayan ecoregion, little is known about the geographic distribution and climatic niche overlap between native and introduced cold‐water species. Here, we used the COUE (centroid shift, overlap, unfilling, and expansion) framework to explore the invasive potential of rainbow (Oncorhynchus mykiss) and brown (Salmo trutta fario) trout and corresponding climatic niche overlap with native snow trout (Schizothorax plagiostomus and Schizothorax richardsonii) in the Indus and Ganges River basins. Although we found more stability in the climatic niche for O. mykiss (93%) than S. trutta (58%), both species do not conserve their climatic niches in this region (p > 0.05). S. trutta has expanded more toward new environmental conditions (42%) compared to O. mykiss (7%). However, there are still available environmental gaps that O. mykiss and S. trutta can potentially occupy in the future. There was a higher overlap in climatic niches between S. plagiostomus and O. mykiss and between S. richardsonii and S. trutta. Observed shifts in climatic niches of these introduced species can negatively affect the transferability of distribution models, which may underestimate the assessments of habitat suitability for introduced trout in the Himalayas. Our study demonstrates that the information on climatic niche dynamics can inform the model‐building process and improve the transferability and predictive performance to better assess vulnerability of sensitive habitats to introduced species in the Himalayas and elsewhere.
The process of adaptation to higher education studies and its relation to academic dropout
Authors: Garcés‐Delgado Yaritza , Fernández‐Esteban Mª. Inmaculada , Álvarez‐Pérez Pedro R. , Conde‐Vélez Sara 
Published: April 2024

AbstractThe academic dropout of higher education students represents one of the most significant challenges that university institutions have to face today. This research analysed the university academic trajectory of students who dropped out of university for good. The aim of this paper is to examine in depth the factors that influence the idea of the construction of academic dropout and its relationship with the difficulties of adaptation to the university training system. A qualitative study was carried out in which the interview technique was applied to n = 34 dropout students belonging to three Spanish autonomous communities. The results made it possible to identify and examine students' difficulties in adapting to university studies in greater depth. The interviews revealed contextual and emotional details that contributed to dropout, such as personal and professional challenges and a lack of emotional support. The findings lead to the need to approach the issue from a holistic viewpoint in order to address the different reasons behind university dropouts. This broad view of the academic trajectories of university students who drop out is a benchmark for strategies to improve student retention and success in higher education.