bluuebunny/crossref_metadata_2025_split huggingface dataset:
LapEfficientDepth: lightweight model for monocular depth estimation based on small samples
Authors: Zhang Guangyuan , Guan Hongliang , Li Kefeng , Wang Zhenfei , Wang Peng , Fu Chen , Zhu Zhenfang 
Published: March 2024

Abstract

This study proposes an improved LapDepth model, named LapEfficientDepth, for the monocular depth estimation field. The objective is to reduce the error in model-predicted relative depths and enhance depth estimation accuracy, addressing the issues of substantial resource consumption and large parameter count inherent in the original model. By incorporating lightweight modules, the LapEfficientDepth model significantly reduces model the complexity and resource requirements of the model while maintaining high accuracy estimation. Specifically, the parameter count of the LapEfficientDepth model has been reduced to 6M, constituting only 8.2% of the parameter volume found in the original LapDepth model, while achieving an approximate 1% improvement in accuracy compared to the Lite-Mono-8M model, which has a similar number of parameters. In addition, the LapEfficientDepth model exhibits exceptional transfer learning capabilities. After pre-training on the KITTI dataset and further training on the ETH3D-S dataset, the model achieved a1, a2, and a3 metrics of 0.706, 0.997, and 0.999, respectively, proving its rapid adaptability and learning ability on small sample datasets. This offers an effective solution for high-performance, lightweight monocular depth estimation network models.
Telehealth-facilitated palliative care enables more people to die at home: An analysis of clinical outcomes and service activity data
Authors: Haydon Helen M , Lotfaliany Mojtaba , Broadbent Andrew , Snoswell Centaine L , Smith Anthony C , Brydon Julie-Ann , Caffery Liam J , Thomas Emma E 
Published: March 2024

Abstract

Background
Telehealth-facilitated models of palliative care are a patient-focused way to deliver specialist care in or closer to home for people with a life-limiting illness. Telehealth can increase access to palliative care and support people experiencing symptoms of advanced disease in their own home, reducing the discomfort of travel. This retrospective cohort study examines the activity and outcomes of a regional telehealth-facilitated palliative care service to i) describe which patients are most likely to use telehealth; and ii) determine the impact of telehealth on patient outcomes including place of death, timely access to care, responsiveness to urgent needs and pain management.
Methods
Analysis of service activity data (patient demographics, care modality, consultation frequency) and Palliative Care Outcomes Collaborative data registry (place of death, timely access to palliative care, responsiveness to urgent needs as measured by time in unstable phase, pain management) were undertaken. Outcomes were compared between patients who had no videoconsultations (n = 683) and those who had one or more videoconsultations (n = 524).
Results
Compared to people who had no videoconsultations, those who had at least one appointment via video were: more than twice as likely to die at home and spent a shorter amount of time in the unstable phase of palliation. Mixed results were found regarding timely access to palliative care. There was no significant difference in pain management between consultation modes.
Conclusion
Telehealth-facilitated palliative care has multiple benefits, including the increased likelihood of fulfilling someone’s wish to die at home, often their preferred place of death.
Exploring the Impact of the JEEViKA Swasthya Mitra Helpdesk Intervention on Improving Healthcare Access in Tertiary Healthcare Facilities in Bihar: A Qualitative Descriptive Evaluation.
Authors: Kumar Pragya , Ahmad Shamshad , Pradhan Narottam , Chaudhary Neha , H Haripriya , Kumari Sarita , G Naveen K , Yadav Akanksha , Jha Rakesh , Pa Ashraf Md. , Swati Swati , Purty Apolenarius , Somya Somya 
Published: March 2024

Abstract

Background: Rural populations in Bihar, India, face significant healthcare access challenges due to geographical, infrastructural, and financial barriers. The Swasthya Mitra program, initiated by the Bihar Rural Livelihood Promotion Society in collaboration with local and international partners, aims to mitigate these challenges by employing trained community members to navigate patients through the healthcare system.
Methods: This qualitative study employed semistructured int erviews and thematic analysis to evaluate the Swasthya Mitra program in the Bhagalpur and Jamui districts in Bihar, India. The participants included Swasthya Mitras, healthcare professionals, and beneficiaries. This study focused on understanding the program's impact on healthcare access, out-of-pocket expenditures, and the role of Swasthya Mitras in facilitating healthcare services.
Findings: The program significantly improved healthcare access for rural populations, with beneficiaries reporting reduced navigational confusion, decreased out-of-pocket expenditures, and enhanced patient care. Swasthya Mitras effectively bridged the gap between the community and healthcare facilities, ensuring timely and efficient medical attention. The program also empowered women, both Swasthya Mitras and beneficiaries, by improving their access to healthcare and increasing their involvement in health-related decision-making.
Interpretation: The Swasthya Mitra program offers a viable model for improving healthcare access in rural settings, demonstrating the importance of community involvement in healthcare delivery. The findings suggest that such programs can be instrumental in overcoming barriers to healthcare access and reducing financial burdens on vulnerable populations.
Screening of PDSS1 as a potential biomarker for hepatocellular carcinoma based on a copper-related prognostic signature through bulk and single-cell RNA-sequencing analysis
Authors: Lin Kainan , Cai Jingwei , Pan Siyuan , Yu Xuefei , Qiu Yiwu , Ying Zhangguo , Feng He , Zhang Lizhuo , Liu Yanyang , Shen Huize , Hong Yangjian , Li Qinglin , Jin Renan 
Published: March 2024

Abstract
Background: Currently, there is few literature comprehensively analyzing landscape of cuproptosis-related genes (CRGs) in liver hepatocellular carcinoma (LIHC) with multiple omics approaches.
Aims: Using comprehensive analysis, we aim to find out how CRGs works on LIHC.
Method: With data from The Cancer Genome Atlas (TCGA) database, we constructed a prognostic prediction model for CGRs using LASSO regression analysis and performed immune infiltration analysis using the same dataset. To validate findings, we utilized RNA expression data from the International Cancer Genome Consortium (ICGC). Furthermore, we analyzed the enrichment and features of CRGs in epithelial cells using single-cell RNA sequencing (scRNA-seq) data. To validate the reliability of findings, we performed several experiments including RT-PCR, cloning formation assay, scratch assay, and Transwell assay.
Result: We have constructed a high-precision risk scoring model composed of CRGs for predicting prognosis in TCGA-LIHC. Reliability of the risk prognosis model was confirmed through Kaplan-Meier curve analysis, time-dependent ROC analysis, and multivariate regression analysis. Furthermore, we found knocking down PDSS1 increased sensitivity of LIHC cells to copper ions, and both proliferation and migration abilities were significantly reduced. Finally, we comprehensively characterized the features of CRGs in LIHC through scRNA-seq.
Conclusion: Current research predicts cuproptosis may be involved in the pathogenesis of LIHC and associated with patient prognosis. Tumor cells with high cuproptosis features are closely related to tumor-associated macrophages (TAMs), which leads to the activation of tumor-related transcription factors (TFs) and a high metabolic microenvironment. Identified CRGs can serve as candidate biomarkers or therapeutic targets for LIHC.
The improvement in electrochemical properties with the addition of SiO2 into PMMA/PLA-LiBOB Gel Polymer Electrolytes Based Lithium Ions Battery
Authors: Khan N. M. , Kufian M. Z. , SAMSUDIN AHMAD SALIHIN 
Published: March 2024

Abstract

The present work investigates the impact of SiO2 nanofiller on the electrochemical properties of gel polymer electrolytes (GPEs) composed of PMMA/PLA-LiBOB. The study encompasses two distinct systems: PMMA/PLA-LiBOB (System I) and PMMA/PLA-LiBOB-SiO2 (System II). Nyquist plots were generated to analyze the samples' bulk resistance (Rb), and it was found that Rb value shows a decreasing trend with the incorporation of SiO2. The ionic conductivity increases from 1.69×10-6 S cm-1 to 1.37×10-3 S cm-1 at room temperature, with the highest composition achieved at 6 wt.% of SiO2. Dielectric properties revealed that the addition of SiO2 nanofiller led to the enhancement of dielectric constant (ε′) and dielectric loss (ε″), attributed to SiO2 nanofiller with high orientation polarizability and space charge polarization effects. Linear Sweep Voltammetry (LSV) measurements from both GPE samples are 4.1 V (System I) and 4.7 V (System II). Comparative electrochemical performances of the batteries assembled in System I and System II were conducted, demonstrating the superiority of System II in terms of stability and cycling performance. The differential capacity analysis further supported the enhanced electrochemical activity upon SiO2 nanofiller incorporation.
Engineering the performance of bifunctional oxygen electrocatalysts by modulating the atomically dispersed Co,Ni on N-doped cotton biomass aerogel of carbon fiber catalysts for rechargeable zinc-air battery
Authors: Yang Zhengyu , Jin Wan , Yang Zhengyu 
Published: March 2024

Abstract
Rational construction of advanced bifunctional catalysts with dual-active-sites is still challenging for both oxygen reduction (ORR) and oxygen evolution reactions (OER).The design of metal single atom catalysts prepared through high-temperature gas transport is an emerging method. The CoNi-N-C catalyst was prepared by using Co powder and Nickel foam to volatilize atomic dispersed Co,Ni element embedded in nitrogen doped cotton biomass biomass aerogel of carbon fibers in a high temperature tubular furnace in ammonia atmosphere. In this work, CoNi-N-C-1000 monoatomic catalyst was successfully synthesized by using the above method The resulting CoNi-N-C-1000 exhibited excellent bifunctional catalytic performance for ORR (E1/2=0.85V) and OER (Ej=10=1.54V) in alkaline electrolytes, which can compete with previously reported bifunctional electrocatalysts. In addition, compared to the Pt/C+RuO2 mixed catalyst, this bifunctional catalyst can endow the self-made zinc-air battery with better power density (128.5 mW/cm2) and cycle stability (142.3 hours), demonstrating its potential feasibility in practical applications of rechargeable zinc-air batteries.
Perceived abusive supervision and suicidal risk in Chinese graduate students: the chain mediating roles of autonomy need and professional identity
Authors: Yao Yingying , Chen Jianqiao , Chi Haoyang , Hang Yaming , Qiao Zhihong 
Published: March 2024

Abstract

Background: The suicide issue of graduate students related to the strained relationships with their academic supervisors has triggered wide concern and heated discussion recently. The study aimed to explore the relationship between abusive supervision graduate students perceived and the suicidal risk of them, and the mediating roles of autonomy need and professional identity.
Method: An online survey was conducted among 233 graduate students and the perceived abusive supervision, autonomy need, professional identity, suicidal ideation, depressive symptoms and psychache (psychological pain) were measured.
Results: It was found that the perceived abusive supervision positively correlated to the latent variable suicidal risk (suicidal ideation, depressive symptoms and paychache as three indicators), and worked through the respective mediating effects of autonomy need, professional identity and the chain mediating effect of them. The total indirect effect size was 0.130, accounting for 27.78% of overall effect size. These findings deepen the understanding of the influence of abusive supervision under high education setting and provided practical insights into psychosocial intervention from the perspective of the self-determination theory and the model of professional identity formation.
Screening for Crimean-Congo Haemorrhagic Fever Virus in humans living in an endemic area of Spain.
Authors: Juanes Helena Miriam Lorenzo , Sardon Montserrat Alonso , Santiago Belen Vicente , Alonso Beatriz Rodriguez , Bernus Amparo Lopez , Ulerio Josue Pendones , Sanz Rufino Alamo , Alvarez Antonio Muro , Bellido Juan Luis Muñoz , Garcia Moncef Belhassen 
Published: March 2024

Abstract

Purpose
Crimean-Congo haemorrhagic fever (CCHF) is a tick-borne disease caused by CCHF virus (CCHFV). CCHF is an emerging infectious disease. Recently, the disease has been described in humans in Spain. Most cases have been described in the central-western area of the Iberian Peninsula. This study aimed to evaluate the seroprevalence of anti-CCHFV antibodies in humans in this endemic area of Spain.
Methods
Study was conducted to estimate the seroprevalence of anti-CCHFV antibodies among patients referred to a hospital located in the central-western area of Spain, an endemic area for CCHFV of Spain. Patients were recruited from April 1, 2023, to June 30, 2023. A commercial ELISA was used to detect anti-CCHFV serum antibodies.
Principal findings
We screened 658 samples from 370 (56.2%) men, with a mean (±SD) age of 58.6 years (± 14.3). Of these, 4 were IgG positive, representing an IgG seropositivity of 0.6% (95% CI, 0.01-1.19). None of these four patients recalled having a clinical picture that strongly suggested CCHF. The incidence of CCHF in the Bejar area was 33.2 cases per 100,000 inhabitants.
Conclusions
Our results suggest active circulation of the virus in humans in western Spain. More extensive clinical and epidemiological studies are needed. Although the risk is considered low, clinicians should be alert to the possibility of new CCHF cases, given the high pathogenicity of CCHFV and the risk of transmission. A detailed medical history of each patient is critical for rapid diagnosis, appropriate adoption of therapeutic measures and timely control of the infection.
Designing equitable telehealth solutions for outpatient surgical care in a safety-net population: a human-centered design approach
Authors: Chehab Lara Z , Mettupalli Diyah , Cevallos Jenny R , Rogine Camille , Sammann Amanda , Kumar Sandhya 
Published: March 2024

Abstract

Background
The SARS CoV-2 (COVID-19) pandemic catalyzed a dramatic shift in healthcare delivery, with telemedicine emerging as a common mode of care provision. While pre-pandemic telemedicine services were more commonly used for preventive visits and had better adherence among younger and more affluent demographics, the landscape of telehealth in the post-pandemic period has shifted significantly to include surgical visits and publicly-insured patient populations. Without specific insights from patients and clinicians to guide this transition, telehealth delivery risks exacerbating disparities in access, experience and outcomes for medically underserved populations.
Methods
We utilized a human-centered design (HCD) approach to gain insights into patient and clinician perspectives on telehealth delivery at a surgical outpatient clinic in an urban safety-net hospital and level 1 trauma center. During the Inspiration phase of HCD, we conducted 19 in-depth interviews with patients and surgical clinicians, and applied a combined thematic analysis and design synthesis approach to identify key insight statements representing actionable tensions across cohorts. During the Ideation phase of HCD, we held a structured brainstorming session to identify solutions and facilitated a discussion with surgical faculty to co-design and refine a prototype.
Results
Interview analysis revealed 12 main themes, which were then reorganized into 5 core insights across both groups: “In-person appointments can be resource intensive for patients, making their attendance costly in more ways than one”; “When sacrificing connection for convenience, telehealth exacerbates discrimination felt by historically marginalized patients”; “Personal interactions are crucial for establishing new relationships and repairing mistrust between patients and clinicians”; “Visual cues and non-verbal communication are essential for personalized and effective surgical care”; “Patients and clinicians value the human infrastructure built into the in-person visit experience.” Brainstorming participants generated ideas from the first insight statement. Subsequent prototyping and co-design sessions led to the development of a screening prototype allowing both clinic staff and patients to book telehealth appropriate appointments.
Conclusions
This study offers a HCD approach to developing insights and tailoring health service interventions to the local contexts for safety-net providers. By understanding the unique needs and preferences of underserved populations, we can develop telehealth interventions that increase adoption and ensure equitable access to care.
Numerical analysis of influencing factors on wafer surface flatness in double-sided chemical mechanical polishing process
Authors: Wang XianGang , Liu Yiran , Yu Wenjie , Zhu Lei , Chen Jiayu , Cao Jun , Li Weimin 
Published: March 2024

Abstract

Enhancing the levelness of the wafer surface can be achieved by increasing the homogeneity of the radial motion speed of the wafer surface in relation to the polishing pad. In order to analyze the effects of the inner and outer pin ring rotational speeds, the equipment structure size, and the upper and lower polishing pad rotational speeds on the uniformity of the radial velocity distribution of the wafer surface with respect to the polishing pads, kinematics equations of the wafer surface relative to the polishing pads were constructed based on the kinematics of the planetary wheel system. The wafer's motion state with respect to the polishing pad is composed of two processes: rotation and revolution. Rotation is the reason for the uneven radial distribution of the wafer's surface speed; The surface velocity of the wafer is optimally dispersed with respect to the polishing pad when the polishing pad's rotational speed equals that of the planetary wheel; Increasing the polishing pad speed can result in a more equal speed distribution in the direction of the wafer radius with respect to the pad when the ratio of the outer pin ring speed N4 to the inner pin ring speed N3 is less than 1; The velocity homogeneity of the wafer in the radius direction can be enhanced by increasing the eccentricity of the wafer with regard to the planetary wheel and the distance between the center of the planetary wheel and the inner pin ring.
Designing and expression of recombinant fusion protein for screening SARS-CoV-2
Authors: G Vinaya Chandu Vidyasagar , PV Janardhan Reddy , M Ghouse , TC Venkateswarlu , PB Kavi Kishor , Suravajhala Prashanth , Polavarapu Rathnagiri 
Published: March 2024

Abstract
Corona virus disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), claimed many-a-lives globally. After the report of the first incidence of the virus, various variants have emerged with each posing a greater threat than its predecessors. Though many advanced diagnostic assays like real time PCR are available for screening of SARS-CoV-2, their applications are being hindered because of accessibility and cost. With the advent of rapid assays for antigenic screening of SARS-CoV-2 made diagnostics far easy as the assays are rapid, cost-effective and can be used at point-of-care settings. In the present study, a fusion construct was made utilising highly immunogenic epitopes from the three important structural proteins of SARS-CoV-2. The protein was expressed; purified and rapid antigen assay was developed. Eight hundred and forty nasopharyngeal swab samples were screened for the evaluation of the developed assay which showed a 37.14%, 96.51% and 100% positivity, sensitivity and specificity respectively. The assay developed was supposed to identify SARS-CoV-2 wild-type as well as variants of concern and variants of importance in real-time conditions.
Knockdown resistance (kdr)-associated organochlorine resistance in mosquito-borne diseases (Culex pipiens): A systematic study of reviews and meta-analysis
Authors: Abbasi Ebrahim , Daliri Salman , Talbalaghi Asghar , Moemenbellah-Fard Mohammad Djaefar , Mehrpouya Fatemeh , ARAB MARYAM HASANZADEH , ASLVAELI ATENA 
Published: March 2024

Abstract
Background
Culex pipiens is the vector of a large number of pathogens in humans. Use of insecticides to deal with this vector is the most important way to controlling it. However, in recent decades, resistance to insecticides has been reported in this vector. One of the main insecticides used to fight this vector is organochlorine insecticides. Accordingly, this study was conducted to investigate the prevalence of Knockdown resistance (kdr) in Culex pipiens against organochlorine insecticides.
Methods
This study was conducted via systematic review and meta-analysis approach in the field of kdr prevalence in Culex pipiens against organochlorine insecticides. Accordingly, during the search in the scientific databases PubMed, Web of Science, Biooan.org, Embase, ProQuest, Scopus, and Google Scholar without time limit until the end of November 2023, all related articles were extracted and analyzed. The statistical analysis of the data was performed using random and fixed effects model in the meta-analysis, Cochran's test, I2 index, and meta-regression by STATA software version 17.
Results
seven studies with a sample size of 2,029 Culex pipiens were included in the meta-analysis process. Based on the findings, the kdr resistance prevalence against Deltamethrin, Malathion, Permethrin, and DDT insecticides was estimated as 30.6%, 42%, 17.9%, and 76.3% respectively. Among them, the highest resistance was observed to DDT and the lowest to Permethrin.
Conclusion
Based on the findings, a large proportion of Culex pipiens mosquitoes were resistant to DDT insecticide. However, this vector was highly sensitive to Deltamethrin, Malathion, and Permethrin insecticides. Given the different resistance ratios in different regions of the world, it is recommended to conduct studies on the prevalence of kdr in Culex pipiens.