bluuebunny/crossref_metadata_2025_split huggingface dataset:
Cloud media video encoding: review and challenges
Authors: Moina-Rivera Wilmer , Garcia-Pineda Miguel , Gutiérrez-Aguado Juan , Alcaraz-Calero Jose M. 
Published: March 2024

AbstractIn recent years, Internet traffic patterns have been changing. Most of the traffic demand by end users is multimedia, in particular, video streaming accounts for over 53%. This demand has led to improved network infrastructures and computing architectures to meet the challenges of delivering these multimedia services while maintaining an adequate quality of experience. Focusing on the preparation and adequacy of multimedia content for broadcasting, Cloud and Edge Computing infrastructures have been and will be crucial to offer high and ultra-high definition multimedia content in live, real-time, or video-on-demand scenarios. For these reasons, this review paper presents a detailed study of research papers related to encoding and transcoding techniques in cloud computing environments. It begins by discussing the evolution of streaming and the importance of the encoding process, with a focus on the latest streaming methods and codecs. Then, it examines the role of cloud systems in multimedia environments and provides details on the cloud infrastructure for media scenarios. After doing a systematic literature review, we have been able to find 49 valid papers that meet the requirements specified in the research questions. Each paper has been analyzed and classified according to several criteria, besides to inspect their relevance. To conclude this review, we have identified and elaborated on several challenges and open research issues associated with the development of video codecs optimized for diverse factors within both cloud and edge architectures. Additionally, we have discussed emerging challenges in designing new cloud/edge architectures aimed at more efficient delivery of media traffic. This involves investigating ways to improve the overall performance, reliability, and resource utilization of architectures that support the transmission of multimedia content over both cloud and edge computing environments ensuring a good quality of experience for the final user.
Future changes in intense tropical cyclone hazards in the Pearl River Delta region: an air-wave-ocean coupled model study
Authors: Li Zhenning , Fung Jimmy C. H. , Wong Mau Fung , Lin Shangfei , Cai Fenying , Lai Wenfeng , Lau Alexis K. H. 
Published: March 2024

AbstractThe Pearl River Delta (PRD) region is highly vulnerable to tropical cyclone (TC)-caused coastal hazards due to its long and meandering shoreline and well-developed economy. With global warming expected to continue or worsen in the rest of the twenty-first century, this study examines the TC impact on the PRD coastal regions by reproducing three intense landfalling TCs, namely Vicente (2012), Hato (2017), Mangkhut (2018), using a sophisticated air-wave-ocean coupled model of high spatial resolution (1-km atmosphere and 500-m wave and ocean). The simulations are conducted using present-day reanalysis data and the same TCs occurring in a pseudo-global warming scenario projected for the 2090s. Results indicate that the coupled model accurately reproduces the air-wave-ocean status during the TC episodes. The 2090s thermodynamic status effectively increases the intensity of intense TCs, leading to more severe coastal hazards including gale, rainstorm, and storm surges and waves. On average, the maximum surface wind speed within 50–200 km to the right of the TC center can increase by 4.3 m/s (+22%). The 99th and the 99.9th percentile of accumulated rainfall will increase from 405 to 475 mm (+17.3%), and from 619 to 735 mm (+18.6%), respectively. The maximum significant wave height at the ocean is lifted by an average of 57 cm (+13.8%), and the coastline typically faces a 40–80 cm increase. The maximum storm surges are lifted by 30–80 cm over the open sea but aggravate much higher along the coastline, especially for narrowing estuaries. For Typhoon Vicente (2012), there is more than a 200 cm wave height increase observed both at open sea and along the coastline. In the 2090s context, a combination of mean sea level rise, storm surge, and wave height can reach more than 300 cm increase in total water level at certain hot-spot coastlines, without considering the superposition of spring tides.
Alya toward exascale: algorithmic scalability using PSCToolkit
Authors: Owen Herbert , Lehmkuhl Oriol , D’Ambra Pasqua , Durastante Fabio , Filippone Salvatore 
Published: March 2024

AbstractIn this paper, we describe an upgrade of the Alya code with up-to-date parallel linear solvers capable of achieving reliability, efficiency and scalability in the computation of the pressure field at each time step of the numerical procedure for solving a Large Eddy Simulation formulation of the incompressible Navier–Stokes equations. We developed a software module in the Alya’s kernel to interface the libraries included in the current version of , a framework for the iterative solution of sparse linear systems, on parallel distributed-memory computers, by Krylov methods coupled to Algebraic MultiGrid preconditioners. The Toolkit has undergone various extensions within the EoCoE-II project with the primary goal of facing the exascale challenge. Results on a realistic benchmark for airflow simulations in wind farm applications show that the solvers significantly outperform the original versions of the Conjugate Gradient method available in the Alya’s kernel in terms of scalability and parallel efficiency and represent a very promising software layer to move the Alya code toward exascale.
About the Alkemade Theorem and the Limits of its Applicability for the Construction of Ternary Liquidus Surfaces
Authors: Stein F. , He C. 
Published: March 2024

AbstractThe Alkemade theorem goes back to a very fundamental paper on the graphical description of thermodynamic equilibrium problems from 1893 (van Rijn van Alkemade in Z Phys Chem 11: 289-327, 1893). It is one of the most helpful implements for the construction of the liquidus surface of ternary phase diagrams. In its original form, it allows to find the direction of falling or increasing temperature along the monovariant reaction lines forming the boundaries of the primary crystallization fields. The theorem is valid for systems with any number of phases; however, its geometrical construction rule is only defined for the case of stoichiometric phases and it is not clear how to apply the theorem in the case of phases with extended homogeneity ranges. Some examples from a ternary, transition-metal-based system containing phases with large homogeneity ranges are presented, and the usefulness and limits of applicability of the theorem are discussed.
Agile-as-a-tool and agile-as-a-culture: a comprehensive review of agile approaches adopting contingency and configuration theories
Authors: Magistretti Stefano , Trabucchi Daniel 
Published: March 2024

Abstract
Today’s world requires new approaches to innovation that leverage continuous testing and pivoting. Speed and the ability to respond to exogenous shocks are becoming increasingly important in both theory and practice. Following the introduction of the Agile Manifesto in 2001, a wide range of industries have adopted agile approaches, which differ from other ways of managing innovation projects by promoting flexibility and the rapid development of new solutions. Despite the proliferation of agile approaches across industries, the literature lacks a systematic understanding of their underlying elements. Therefore, we conduct a systematic literature review using a text mining technique to longitudinally explore the evolutionary dynamics of the field. Analyzing the results through the dichotomous lens of contingency and configuration theories, we show that the agile literature can be systematized into two perspectives: agile-as-a-tool in the contingency perspective, and agile-as-a-culture in the configuration perspective. Our review reveals underexplored intersections in the field of innovation and provides interesting insights into these two perspectives. We also propose a research agenda to shed light on these emerging perspectives in the agile innovation and management literature.
Direct Minimization of the Canham–Helfrich Energy on Generalized Gauss Graphs
Authors: Kubin Anna , Lussardi Luca , Morandotti Marco 
Published: March 2024

AbstractThe existence of minimizers of the Canham–Helfrich functional in the setting of generalized Gauss graphs is proved. As a first step, the Canham–Helfrich functional, usually defined on regular surfaces, is extended to generalized Gauss graphs, then lower semicontinuity and compactness are proved under a suitable condition on the bending constants ensuring coerciveness; the minimization follows by the direct methods of the Calculus of Variations. Remarks on the regularity of minimizers and on the behavior of the functional in case there is lack of coerciveness are presented.
Marsupials (Herpetotheriids) from the late Palaeogene of south-east Serbia
Authors: Wessels Wilma , van de Weerd Andrew A. , Marković Zoran 
Published: March 2024

AbstractThree marsupial species are present in Palaeogene assemblages from south-eastern Serbia, Amphiperatherium minutum (Aymard, 1846), A. exile (Gervais, 1848–1852) and a species of Peratherium Aymard, 1850. These species are common in the late Eocene and early Oligocene of Western and Central Europe and their presence in South-Eastern Europe indicate that by the end of the Eocene, the eastwards dispersal of these marsupial species was already a fact. The presence of the same marsupial species in Serbia and in Western Europe is surprising, as the difference in composition between the Serbian and Western European rodent faunas indicates a limited faunal exchange between these areas in the late Eocene and early Oligocene. In marsupials, the stylar shelf of the upper molars shows a large morphological variation. A lesser-known variation is the presence of a transverse crista in the stylar shelf. These occur in various marsupial species, but so far were not known to be present in Amphiperatherium minutum. In our opinion, the large morphological variation of the stylar shelf is thus better not used to define a new species.
Large-scale agricultural investments and local food security – Evidence from a mixed-method case study in Benin
Authors: Muder Anika , Luckmann Jonas , Schmid Julia C. 
Published: March 2024

AbstractLarge-scale agricultural investments (LSAIs) and their impacts on local communities in host countries have been controversially discussed in recent years. As scholars increasingly call for more structured and comprehensive analyses, we develop a mixed-method approach using an expanded version of the “Right to Food” (RtF) framework to systematically investigate the local food security impacts of a recently established tomato-producing LSAI in Central Benin, West Africa. We find that the LSAI keeps natural resources as accessible as possible for the local community and provides employment opportunities, leading to higher dietary diversity of employees and multiplier effects in the local economy. At the same time, we find inequalities regarding the compensation of former land users as well as high job insecurity for temporary laborers who face high transportation costs to reach the LSAI. We argue that fair and inclusive compensation, improved access to markets and machinery, access to natural resources for often overlooked groups (pastoralists, hunters, fishermen) and social infrastructure are crucial factors in promoting positive outcomes of LSAIs on communities and that strong local institutions play a key role for achieving this. We conclude that the specific characteristics of our case (relatively small size, labor-intensive crop, focus on regional markets) provide favorable conditions for positive impacts on local food security. We encourage further, structured mixed-method studies, ideally including longitudinal and comparative research designs, to investigate the multidimensional effects related to the establishment of LSAIs. The extended RtF framework can thereby serve as a structural lens to systematically analyze the findings.
Transcriptome and single-cell transcriptomics reveal prognostic value and potential mechanism of anoikis in skin cutaneous melanoma
Authors: Liu Xing , Zhang Hong-Yan , Deng Hong-Ao 
Published: March 2024

Abstract
Background
Skin cutaneous melanoma (SKCM) is a highly lethal cancer, ranking among the top four deadliest cancers. This underscores the urgent need for novel biomarkers for SKCM diagnosis and prognosis. Anoikis plays a vital role in cancer growth and metastasis, and this study aims to investigate its prognostic value and mechanism of action in SKCM.

Methods
Utilizing consensus clustering, the SKCM samples were categorized into two distinct clusters A and B based on anoikis-related genes (ANRGs), with the B group exhibiting lower disease-specific survival (DSS). Gene set enrichment between distinct clusters was examined using Gene Set Variation Analysis (GSVA) and the Kyoto Encyclopedia of Genes and Genomes (KEGG) analysis.

Results
We created a predictive model based on three anoikis-related differently expressed genes (DEGs), specifically, FASLG, IGF1, and PIK3R2. Moreover, the mechanism of these prognostic genes within the model was investigated at the cellular level using the single-cell sequencing dataset GSE115978. This analysis revealed that the FASLG gene was highly expressed on cluster 1 of Exhausted CD8( +) T (Tex) cells.

Conclusions
In conclusion, we have established a novel classification system for SKCM based on anoikis, which carries substantial clinical implications for SKCM patients. Notably, the elevated expression of the FASLG gene on cluster 1 of Tex cells could significantly impact SKCM prognosis through anoikis, thus offering a promising target for the development of immunotherapy for SKCM.
DDOST is associated with tumor immunosuppressive microenvironment in cervical cancer
Authors: Mei Jie , Pan Liuliu , Huang Min , Bao Dandan , Gao Hui , Wang Danhan 
Published: March 2024

AbstractEvidence has revealed that DDOST plays an important role in cancer development and progression. However, there are no reports on functions of DDOST in cervical tumorigenesis. Hence, we investigated the relationship of DDOST with prognosis, mutation, promoter methylation, immune cell infiltration, and drug sensitivity using bioinformatics techniques. Our results demonstrated that DDOST was significantly upregulated in a variety of tumor types and correlated with poor prognosis, including cervical cancer. Cox regression analysis dissected that high DDOST expression was associated with poor survival in cervical cancer patients. Immune infiltration analysis defined that DDOST was negatively correlated with CD8 T cells and NK cells. Strikingly, the sensitivity to multiple drugs was negatively correlated with the expression of DDOST. Therefore, our findings uncovered that DDOST could play an essential role in the tumor microenvironment and tumor immune regulation in cervical cancer, which indicated that DDOST could be a useful biomarker for prognosis and a potential therapeutic target for cancer treatment.
Investigation of media for wheat (Triticum aestivum L.) immature embryo culture
Authors: Mohammed Abdullah Hassn , Baldwin Brian S. 
Published: March 2024

AbstractImmature embryos of F1 progeny resulting from taxonomically wide hybridizations require tissue culture using complex media to mature, grow and develop into normal and healthy plants. To gain insight as to how progeny of wide-crosses between wild and domestic Triticum species, 12 domestic varieties (Al-Eiz, Babel, Bedhaa, Entisar, Hadbaa, IPA 99, Latifia, Nour, Rabia, Sally, Sham 6, Tamoz 2) were used to determine the genotype response to culture media type. Immature embryos the aforementioned wheat varieties were screened on four media (Murashige and Skoog; MS full strength, ½ strength MS, Gamborg B-5; B-5 full strength, and ½ strength B-5) to determine performance when used as a female in a cross with wild species. The experiment used a completely randomized design with six replications. Traits recorded were final germinations percentage (FGP), shoot length (SL), root length (RL), and root number (RN). Results indicated significant variety x media interaction for all traits studied. Despite the interaction, in a practical sense, all varieties performed adequately on ½ B-5 and varieties Al-Eiz, Entisar, Hadbaa, and Latifia performed well on any of the four media. Tamoz 2 behaved recalcitrantly on all media tested. Data from this study indicated genetic variability among these wheat varieties caused substantial differences in response to each type of media.
Enhancing Steel Wheel Ventilation Efficiency Through Multi-Objective Optimization
Authors: Bogrekci I. , Demircioglu P. , Sasmaz M. E. , Unal C. 
Published: March 2024

AbstractThis study focuses on the optimization of ventilation hole design in steel wheels used for heavy commercial vehicles. The primary objective is to reduce the weight of the wheel while ensuring compliance with radial fatigue and cornering fatigue test requirements. Four distinct ventilation types were parametrized using ANSYS Mechanical, with the von Mises stress on the disk, number of ventilations, and wheel weight serving as design parameters. Stress analysis and weight comparisons were performed between wheels featuring different ventilation types and an ellipse ventilation wheel. Incorporating the design of experiment (DoE) and response surface optimization (RSO) module in ANSYS Workbench 2022 R1 was employed to compare and evaluate the obtained values. Subsequently, the multi-objective genetic algorithm (MOGA-II) method was employed for optimization, aiming to identify the optimal design. The optimization process, utilizing a maximum of 20 iterations, a convergence stability percentage of 2%, and a maximum allowable Pareto percentage of 70%, yielded 1, 3, 3, and 3 candidate design points for round, slot, trapezoid, and halfmoon-type ventilation holes, respectively. Among the various ventilation types considered, the halfmoon-type ventilation hole exhibited the most promising results. Compared to the current design, the optimized wheel achieved a weight reduction of 0.9 kg (2.05%). This outcome demonstrates the effectiveness of the proposed methodology. Although lighter designs were not attainable while maintaining the same stress values for the other three ventilation types, the halfmoon-type ventilation hole was ultimately selected as the preferred design.
Unlocking the power of motor imagery: a comprehensive review on its application in alleviating foot pain
Authors: Tedeschi Roberto 
Published: March 2024

Abstract
Background
Motor imagery is a cognitive process that involves mentally simulating movements without physical execution. It has been studied in the context of foot pain to understand the role of motor cortical reorganization and its impact on motor imagery abilities. However, further research is needed to establish consistent evidence regarding the relationship between motor imagery and foot pain.

Methods
This review analyzed five relevant articles that investigated motor imagery in the context of foot pain. The studies involved participants with various conditions, including leg amputation, chronic leg pain, complex regional pain syndrome, and Achilles tendinopathy. Different methodologies were employed, including motor cortical mapping, foot laterality recognition tasks, EEG recordings, and treatment interventions incorporating motor imagery.

Results
The findings indicated that individuals with leg amputation exhibited functional reorganization in upper limb motor cortical maps, with a breakdown in the inhibitory relationship between foot and hand representations. Participants with chronic leg pain demonstrated slower and less accurate performance on foot laterality recognition tasks compared to healthy controls. Complex regional pain syndrome patients displayed distinct motor imagery strategies and responded differently to first-person and third-person perspectives. EEG studies revealed differences in brain activity during motor imagery tasks under pain-free and pain conditions. Treatment interventions incorporating motor imagery showed promising outcomes in improving functional outcomes and reducing pain levels.

Conclusions
Motor imagery plays a significant role in foot pain conditions, although the evidence is still emerging. The findings suggest that motor imagery abilities may be affected by leg amputation, chronic pain, and complex regional pain syndrome. Further research is needed to establish standardized protocols for assessing motor imagery, identify specific patient populations that may benefit most from motor imagery interventions, and explore long-term effects. Integrating motor imagery into clinical practice has the potential to enhance rehabilitation approaches and improve outcomes in foot pain management.
Development and Validation of the Adolescent and Children Risk of Abuse and Maltreatment Unaccompanied Scale (ACRAM-US)
Authors: Samper Paula , García-Mollá Adrián , Tomás José M. , Marco-Arocas Elisabet 
Published: March 2024

AbstractIndependent migration of children and adolescents is becoming a political and social issue in recent years. Literature documents that the migration process of young people without an adult referent entail serious psychological problems. Moreover, the lack of coherence in the assessment and care processes aggravates the damage suffered by minors, which requires a greater investment of institutional resources. The aim of this research is to describe the development and provide psychometric properties of Adolescent and Children Risk of Abuse and Maltreatment Unaccompanied Scale (ACRAM-US), a 9-items scale for the assessment of risks factors of child abuse and neglect in the specific population of unaccompanied asylum-seeking children and adolescents. Structural validity, reliability and convergent-related validity were studied for this measure in a sample of 128 unaccompanied children and adolescents. The sample included cases of 14 different nationalities. Children’s mean age was 16.94 (SD = 1.84), and 96.9% were male and 3.1% were female. Cases were informed by child welfare workers from different protective services in the XXXX Community (XXXX). The results of Exploratory Factor Analyses (EFA) indicate performance better solution with 2-dimensions which was also in line with theoretical formulation (χ2 = 31.55, df = 19, p = .035, CFI = 0.991, SRMR = 0.081, RMSEA = 0.072, [90% CI: 0.019 − 0.115]). Results of convergent validity showed significant correlation with the Children Trauma Questionnaire-Short Form (CTQ-SF). Therefore, this study provides data of the first scale that assess risks factors of maltreatment for the unaccompanied asylum-seeking children and adolescents.