bluuebunny/crossref_metadata_2025_split huggingface dataset:
Ultrafast Non‐Volatile Floating‐Gate Memory Based on All‐2D Materials
Authors: Wang Hao , Guo Hui , Guzman Roger , JiaziLa Nuertai , Wu Kang , Wang Aiwei , Liu Xuanye , Liu Li , Wu Liangmei , Chen Jiancui , Huan Qing , Zhou Wu , Yang Haitao , Pantelides Sokrates T. , Bao Lihong , Gao Hong‐Jun 
Published: March 2024

AbstractThe explosive growth of massive‐data storage and the demand for ultrafast data processing require innovative memory devices with exceptional performance. 2D materials and their van der Waal heterostructures with atomically sharp interfaces hold great promise for innovations in memory devices. Here, this work presents non‐volatile, floating‐gate memory devices with all functional layers made of 2D materials, achieving ultrafast programming/erasing speeds (20 ns), high extinction ratios (up to 108), and multi‐bit storage capability. These devices also exhibit long‐term data retention exceeding 10 years, facilitated by a high gate‐coupling ratio (GCR) and atomically sharp interfaces between functional layers. Additionally, this work demonstrates the realization of an “OR” logic gate on a single‐device unit by synergistic electrical and optical operations. The present results provide a solid foundation for next‐generation ultrahigh‐speed, ultralong lifespan, non‐volatile memory devices, with a potential for scale‐up manufacturing and flexible electronics applications.
In‐Synthesis Se‐Stabilization Enables Defect and Doping Engineering of HgTe Colloidal Quantum Dots
Authors: Yu Mengxuan , Yang Ji , Zhang Xingchen , Yuan Mohan , Zhang Jianbing , Gao Liang , Tang Jiang , Lan Xinzheng 
Published: March 2024

AbstractColloidal Quantum Dots (CQDs) of mercury telluride (HgTe) hold particular appeal for infrared photodetection due to their widely tunable infrared absorption and good compatibility with silicon electronics. While advances in surface chemistry have led to improved CQD solids, the chemical stability of HgTe material is not fully emphasized. In this study, it is aimed to address this issue and identifies a Se‐stabilization strategy based on the surface coating of Se on HgTe CQDs via engineering in the precursor reactivity. The presence of Se‐coating enables HgTe CQDs with improved colloidal stability, passivation, and enhanced degree of freedom in doping tuning. This enables the construction of optimized p‐i‐n HgTe CQD infrared photodetectors with an ultra‐low dark current 3.26 × 10−6 A cm⁻2 at −0.4 V and room‐temperature specific detectivity of 5.17 × 1011 Jones at wavelength ≈2 um, approximately one order of magnitude improvement compared to that of the control device. The stabilizing effect of Se is well preserved in the thin film state, contributing to much improved device stability. The in‐synthesis Se‐stabilization strategy highlights the importance of the chemical stability of materials for the construction of semiconductor‐grade CQD solids and may have important implications for other high‐performance CQD optoelectronic devices.
CogniFiber: Harnessing Biocompatible and Biodegradable 1D Collagen Nanofibers for Sustainable Nonvolatile Memory and Synaptic Learning Applications
Authors: Rokade Kasturi A. , Kumbhar Dhananjay D. , Patil Snehal L. , Sutar Santosh S. , More Krantiveer V. , Dandge Padma B. , Kamat Rajanish K. , Dongale Tukaram D. 
Published: March 2024

AbstractHere, resistive switching (RS) devices are fabricated using naturally abundant, nontoxic, biocompatible, and biodegradable biomaterials. For this purpose, 1D chitosan nanofibers (NFs), collagen NFs, and chitosan–collagen NFs are synthesized by using an electrospinning technique. Among different NFs, the collagen‐NFs‐based device shows promising RS characteristics. In particular, the optimized Ag/collagen NFs/fluorine‐doped tin oxide RS device shows a voltage‐tunable analog memory behavior and good nonvolatile memory properties. Moreover, it can also mimic various biological synaptic learning properties and can be used for pattern classification applications with the help of the spiking neural network. The time series analysis technique is employed to model and predict the switching variations of the RS device. Moreover, the collagen NFs have shown good cytotoxicity and anticancer properties, suggesting excellent biocompatibility as a switching layer. The biocompatibility of collagen NFs is explored with the help of NRK‐52E (Normal Rat Kidney cell line) and MCF‐7 (Michigan Cancer Foundation‐7 cancer cell line). Additionally, the biodegradability of the device is evaluated through a physical transient test. This work provides a vital step toward developing a biocompatible and biodegradable switching material for sustainable nonvolatile memory and neuromorphic computing applications.
New Carbon Materials for Multifunctional Soft Electronics
Authors: Xue Jie , Liu Dan , Li Da , Hong Tianzeng , Li Chuanbing , Zhu Zifu , Sun Yuxuan , Gao Xiaobo , Guo Lei , Shen Xi , Ma Pengcheng , Zheng Qingbin 
Published: March 2024

AbstractSoft electronics are garnering significant attention due to their wide‐ranging applications in artificial skin, health monitoring, human–machine interaction, artificial intelligence, and the Internet of Things. Various soft physical sensors such as mechanical sensors, temperature sensors, and humidity sensors are the fundamental building blocks for soft electronics. While the fast growth and widespread utilization of electronic devices have elevated life quality, the consequential electromagnetic interference (EMI) and radiation pose potential threats to device precision and human health. Another substantial concern pertains to overheating issues that occur during prolonged operation. Therefore, the design of multifunctional soft electronics exhibiting excellent capabilities in sensing, EMI shielding, and thermal management is of paramount importance. Because of the prominent advantages in chemical stability, electrical and thermal conductivity, and easy functionalization, new carbon materials including carbon nanotubes, graphene and its derivatives, graphdiyne, and sustainable natural‐biomass‐derived carbon are particularly promising candidates for multifunctional soft electronics. This review summarizes the latest advancements in multifunctional soft electronics based on new carbon materials across a range of performance aspects, mainly focusing on the structure or composite design, and fabrication method on the physical signals monitoring, EMI shielding, and thermal management. Furthermore, the device integration strategies and corresponding intriguing applications are highlighted. Finally, this review presents prospects aimed at overcoming current barriers and advancing the development of state‐of‐the‐art multifunctional soft electronics.
Engineering Covalent Organic Frameworks Toward Advanced Zinc‐Based Batteries
Authors: Zhang Qingqing , Zhi Peng , Zhang Jing , Duan Siying , Yao Xinyue , Liu Shude , Sun Zhefei , Jun Seong Chan , Zhao Ningning , Dai Lei , Wang Ling , Wu Xianwen , He Zhangxing , Zhang Qiaobao 
Published: March 2024

AbstractZinc‐based batteries (ZBBs) have demonstrated considerable potential among secondary batteries, attributing to their advantages including good safety, environmental friendliness, and high energy density. However, ZBBs still suffer from issues such as the formation of zinc dendrites, occurrence of side reactions, retardation of reaction kinetics, and shuttle effects, posing a great challenge for practical applications. As promising porous materials, covalent organic frameworks (COFs) and their derivatives have rigid skeletons, ordered structures, and permanent porosity, which endow them with great potential for application in ZBBs. This review, therefore, provides a systematic overview detailing on COFs structure pertaining to electrochemical performance of ZBBs, following an in depth discussion of the challenges faced by ZBBs, which includes dendrites and side reactions at the anode, as well as dissolution, structural change, slow kinetics, and shuttle effect at the cathode. Then, the structural advantages of COF‐correlated materials and their roles in various ZBBs are highlighted. Finally, the challenges of COF‐correlated materials in ZBBs are outlined and an outlook on the future development of COF‐correlated materials for ZBBs is provided. The review would serve as a valuable reference for further research into the utilization of COF‐correlated materials in ZBBs.
High‐Performance Tandem Quantum‐Dot Light‐Emitting Diodes Based on Bulk‐Heterojunction‐Like Charge‐Generation Layers
Authors: Zhou Taiying , Wang Ting , Bai Jialin , Liu Shihao , Zhang Hanzhuang , Xie Wenfa , Ji Wenyu 
Published: March 2024

AbstractIn this study, the fundamental but previously overlooked factors of charge generation efficiency and light extraction efficiency (LEE) are explored and collaboratively optimized in tandem quantum‐dot light‐emitting diodes (QLEDs). By spontaneously forming a microstructured interface, a bulk‐heterojunction‐like charge‐generation layer composed of a poly(3,4‐ethylenedioxythiophene):poly(styrene sulfonate)/ZnO bilayer is fabricated and an ideal charge‐generation efficiency surpassing 115% is obtained. The coupling strength of the waveguide mode for the top unit and the plasmon polariton loss for the bottom unit are highly suppressed using precise thickness control, which increases the LEE of the tandem devices. The red tandem QLED achieves an exceptionally low turn‐on voltage for electroluminescence at 4.0 V and outstanding peak external quantum efficiency of 42.9%. The ultralow turn‐on voltage originates from the sequential electroluminescence turn‐on of the two emissive units of the tandem QLED. Benefiting from its unique electroluminescent features, an easily fabricated optical‐electrical dual anti‐counterfeiting display is built by combining a dichromatic tandem QLED with masking technology.
Silver‐catalyzed Cascade Bis‐heteroannulation Reaction of Enynones and o‐Hydroxyphenyl Enaminones: Access to Highly Functionalized 3‐Furylmethyl Chromones
Authors: Zhang Mingshuai , Liu Meichen , Qiu Yuetong , Peng Menglin , Zhang Zhilai , Song Siyu , Chen Xue‐Bing , Yu Fuchao 
Published: March 2024

AbstractA synthetic protocol was developed to synthesize highly functionalized 3‐furylmethyl chromones from enynones and o‐hydroxyphenyl enaminones via silver‐catalyzed cascade bis‐heteroannulation reaction. This strategy features broad substrate scope and good functional group tolerance. Furthermore, the 3‐furylmethyl chromone skeleton shows the potential synthetic application value through further gram‐scale synthesis and derivatization.
Catalytic Asymmetric Dearomative Arylation of 2‐Naphthols Enabled by o‐Quinone Diimides
Authors: Li Yuan‐Yang , Yang Fu‐Yuan , Wu Meng‐Yuan , Huang Lihua , Mei Guang‐Jian 
Published: March 2024

AbstractThe catalytic asymmetric dearomative arylation of 2‐naphthols enabled by the unconventional reactivity of o‐quinone diimides, i. e. the 1,4‐conjugate addition on quinone sp2 hybridized carbon, has been established. Under the catalysis of chiral phosphoric acid, various cyclohexaenones bearing an all‐carbon quaternary stereocenter have been prepared with excellent yields and enantioselectivities.
Paintable Decellularized‐ECM Hydrogel for Preventing Cardiac Tissue Damage
Authors: Lee Jaewoo , Lee Seul‐Gi , Kim Beom‐seok , Park Shinhye , Sundaram M. Nivedhitha , Kim Byung‐gee , Kim C‐Yoon , Hwang Nathaniel S. 
Published: March 2024

AbstractThe tissue‐specific heart decellularized extracellular matrix (hdECM) demonstrates a variety of therapeutic advantages, including fibrosis reduction and angiogenesis. Consequently, recent research for myocardial infarction (MI) therapy has utilized hdECM with various delivery techniques, such as injection or patch implantation. In this study, a novel approach for hdECM delivery using a wet adhesive paintable hydrogel is proposed. The hdECM‐containing paintable hydrogel (pdHA_t) is simply applied, with no theoretical limit to the size or shape, making it highly beneficial for scale‐up. Additionally, pdHA_t exhibits robust adhesion to the epicardium, with a minimal swelling ratio and sufficient adhesion strength for MI treatment when applied to the rat MI model. Moreover, the adhesiveness of pdHA_t can be easily washed off to prevent undesired adhesion with nearby organs, such as the rib cages and lungs, which can result in stenosis. During the 28 days of in vivo analysis, the pdHA_t not only facilitates functional regeneration by reducing ventricular wall thinning but also promotes neo‐vascularization in the MI region. In conclusion, the pdHA_t presents a promising strategy for MI treatment and cardiac tissue regeneration, offering the potential for improved patient outcomes and enhanced cardiac function post‐MI.
In Vivo Intelligent Fluorescence Endo‐Microscopy by Varifocal Meta‐Device and Deep Learning
Authors: Chia Yu‐Hsin , Liao Wei‐Hao , Vyas Sunil , Chu Cheng Hung , Yamaguchi Takeshi , Liu Xiaoyuan , Tanaka Takuo , Huang Yi‐You , Chen Mu Ku , Chen Wen‐Shiang , Tsai Din Ping , Luo Yuan 
Published: March 2024

AbstractEndo‐microscopy is crucial for real‐time 3D visualization of internal tissues and subcellular structures. Conventional methods rely on axial movement of optical components for precise focus adjustment, limiting miniaturization and complicating procedures. Meta‐device, composed of artificial nanostructures, is an emerging optical flat device that can freely manipulate the phase and amplitude of light. Here, an intelligent fluorescence endo‐microscope is developed based on varifocal meta‐lens and deep learning (DL). The breakthrough enables in vivo 3D imaging of mouse brains, where varifocal meta‐lens focal length adjusts through relative rotation angle. The system offers key advantages such as invariant magnification, a large field‐of‐view, and optical sectioning at a maximum focal length tuning range of ≈2 mm with 3 µm lateral resolution. Using a DL network, image acquisition time and system complexity are significantly reduced, and in vivo high‐resolution brain images of detailed vessels and surrounding perivascular space are clearly observed within 0.1 s (≈50 times faster). The approach will benefit various surgical procedures, such as gastrointestinal biopsies, neural imaging, brain surgery, etc.
Enhancing Tumor Immunotherapy by Multivalent Anti‐PD‐L1 Nanobody Assembled via Ferritin Nanocage
Authors: Liu Manman , Jin Duo , Yu Wenxin , Yu Jiaji , Cao Kaiming , Cheng Junjie , Zheng Xiaohu , Wang Andrew , Liu Yangzhong 
Published: March 2024

AbstractIncreasing immunotherapy response rate and durability can lead to significant improvements in cancer care. To address this challenge, a novel multivalent immune checkpoint therapeutic platform is constructed through site‐specific ligation of anti‐PD‐L1 nanobody (Nb) on ferritin (Ftn) nanocage. Nb‐Ftn blocks PD‐1/PD‐L1 interaction and downregulates PD‐L1 levels via endocytosis‐induced degradation. In addition, the cage structure of Ftn allows encapsulation of indocyanine green (ICG), an FDA‐approved dye. Photothermal treatment with Nb‐Ftn@ICG induces immunogenic death of tumor cells, which improves systemic immune response via maturation of dendritic cells and enhanced infiltration of T cells. Moreover, Nb‐Ftn encapsulation significantly enhances cellular uptake, tumor accumulation and retention of ICG. In vivo assays showed that this nanoplatform ablates the primary tumor, suppresses abscopal tumors and inhibits tumor metastasis, leading to a prolonged survival rate. This work presents a novel strategy for improving cancer immunotherapy using multivalent nanobody‐ferritin conjugates as immunological targeting and enhancing carriers.
In Vitro Transcribed mRNA Immunogenicity Induces Chemokine‐Mediated Lymphocyte Recruitment and Can Be Gradually Tailored by Uridine Modification
Authors: Drzeniek Norman M. , Kahwaji Nourhan , Picht Samira , Dimitriou Ioanna Maria , Schlickeiser Stephan , Moradian Hanieh , Geissler Sven , Schmueck‐Henneresse Michael , Gossen Manfred , Volk Hans‐Dieter 
Published: March 2024

AbstractBeyond SARS‐CoV2 vaccines, mRNA drugs are being explored to overcome today's greatest healthcare burdens, including cancer and cardiovascular disease. Synthetic mRNA triggers immune responses in transfected cells, which can be reduced by chemically modified nucleotides. However, the side effects of mRNA‐triggered immune activation on cell function and how different nucleotides, such as the N1‐methylpseudouridine (m1Ψ) used in SARS‐CoV2 vaccines, can modulate cellular responses is not fully understood. Here, cellular responses toward a library of uridine‐modified mRNAs are investigated in primary human cells. Targeted proteomics analyses reveal that unmodified mRNA induces a pro‐inflammatory paracrine pattern marked by the secretion of chemokines, which recruit T and B lymphocytes toward transfected cells. Importantly, the magnitude of mRNA‐induced changes in cell function varies quantitatively between unmodified, Ψ‐, m1Ψ‐, and 5moU‐modified mRNA and can be gradually tailored, with implications for deliberately exploiting this effect in mRNA drug design. Indeed, both the immunosuppressive effect of stromal cells on T‐cell proliferation, and the anti‐inflammatory effect of IL‐10 mRNA are enhanced by appropriate uridine modification. The results provide new insights into the effects of mRNA drugs on cell function and cell‐cell communication and open new possibilities to tailor mRNA‐triggered immune activation to the desired pro‐ or anti‐inflammatory application.
Defect Engineering of Hexagonal MAB Phase Ti2InB2 as Anode of Lithium‐Ion Battery with Excellent Cycling Stability
Authors: Shen Qing , Shi Yang , He Yibo , Wang Junjie 
Published: March 2024

AbstractHexagonal MAB phases （h‐MAB） have attracted attention due to their potential to exfoliate into MBenes, similar to MXenes, which are predicted to be promising for Li‐ion battery applications. However, the high cost of synthesizing MBenes poses challenges for their use in batteries. This study presents a novel approach where a simple ball‐milling treatment is employed to enhance the purity of the h‐MAB phase Ti2InB2 and introduce significant indium defects, resulting in improved conductivity and the creation of abundant active sites. The synthesized Ti2InB2 with indium defects (VIn‐Ti2InB2) exhibits excellent electrochemical properties, particularly exceptional long‐cycle stability at current densities of 5 A g−1 (5000 cycles, average capacity decay of 0.0018%) and 10 A g−1 (15 000 cycles, average capacity decay of 0.093%). The charge storage mechanism of VIn‐Ti2InB2, involving a dual redox reaction, is proposed, where defects promote the In‐Li alloy reaction and a redox reaction with Li in the TiB layer. Finally, a Li‐ion full cell demonstrates cycling stability at 0.5 A g−1 after 350 cycles. This work presents the first accessible and scalable application of VIn‐Ti2InB2 as a Li‐ion anode, unlocking a wealth of possibilities for sustainable electrochemical applications of h‐MAB phases.
An Antibiotic Nanobomb Constructed from pH‐Responsive Chemical Bonds in Metal‐Phenolic Network Nanoparticles for Biofilm Eradication and Corneal Ulcer Healing
Authors: Gao Qiang , Chu Xiaoying , Yang Jie , Guo Yishun , Guo Hanwen , Qian Siyuan , Yang Ying‐Wei , Wang Bailiang 
Published: March 2024

AbstractIn the treatment of refractory corneal ulcers caused by Pseudomonas aeruginosa, antibacterial drugs delivery faces the drawbacks of low permeability and short ocular surface retention time. Hence, novel positively‐charged modular nanoparticles (NPs) are developed to load tobramycin (TOB) through a one‐step self‐assembly method based on metal‐phenolic network and Schiff base reaction using 3,4,5‐trihydroxybenzaldehyde (THBA), ε‐poly‐ʟ‐lysine (EPL), and Cu2+ as matrix components. In vitro antibacterial test demonstrates that THBA‐Cu‐TOB NPs exhibit efficient instantaneous sterilization owing to the rapid pH responsiveness to bacterial infections. Notably, only 2.6 µg mL−1 TOP is needed to eradicate P. aeruginosa biofilm in the nano‐formed THBA‐Cu‐TOB owing to the greatly enhanced penetration, which is only 1.6% the concentration of free TOB (160 µg mL−1). In animal experiments, THBA‐Cu‐TOB NPs show significant advantages in ocular surface retention, corneal permeability, rapid sterilization, and inflammation elimination. Based on molecular biology analysis, the toll‐like receptor 4 and nuclear factor kappa B signaling pathways are greatly downregulated as well as the reduction of inflammatory cytokines secretions. Such a simple and modular strategy in constructing nano‐drug delivery platform offers a new idea for toxicity reduction, physiological barrier penetration, and intelligent drug delivery.
Ru/Ir‐Based Electrocatalysts for Oxygen Evolution Reaction in Acidic Conditions: From Mechanisms, Optimizations to Challenges
Authors: Qin Rong , Chen Guanzhen , Feng Xueting , Weng Jiena , Han Yunhu 
Published: March 2024

AbstractThe generation of green hydrogen by water splitting is identified as a key strategic energy technology, and proton exchange membrane water electrolysis (PEMWE) is one of the desirable technologies for converting renewable energy sources into hydrogen. However, the harsh anode environment of PEMWE and the oxygen evolution reaction (OER) involving four‐electron transfer result in a large overpotential, which limits the overall efficiency of hydrogen production, and thus efficient electrocatalysts are needed to overcome the high overpotential and slow kinetic process. In recent years, noble metal‐based electrocatalysts (e.g., Ru/Ir‐based metal/oxide electrocatalysts) have received much attention due to their unique catalytic properties, and have already become the dominant electrocatalysts for the acidic OER process and are applied in commercial PEMWE devices. However, these noble metal‐based electrocatalysts still face the thorny problem of conflicting performance and cost. In this review, first, noble metal Ru/Ir‐based OER electrocatalysts are briefly classified according to their forms of existence, and the OER catalytic mechanisms are outlined. Then, the focus is on summarizing the improvement strategies of Ru/Ir‐based OER electrocatalysts with respect to their activity and stability over recent years. Finally, the challenges and development prospects of noble metal‐based OER electrocatalysts are discussed.
Highly Sensitive Iontronic Pressure Sensor with Side‐by‐Side Package Based on Alveoli and Arch Structure
Authors: Ding Zhi , Li Weijian , Wang Weidong , Zhao Zhengqian , Zhu Ye , Hou Baoyin , Zhu Lijie , Chen Ming , Che Lufeng 
Published: March 2024

AbstractFlexible pressure sensors play a significant role in wearable devices and electronic skin. Iontronic pressure sensors with high sensitivity, wide measurement range, and high resolution can meet requirements. Based on the significant deformation characteristics of alveoli to improve compressibility, and the ability of the arch to disperse vertical pressure into horizontal thrust to increase contact area, a graded hollow ball arch (GHBA) microstructure is proposed, greatly improving sensitivity. The fabrication of GHBA ingeniously employs a double‐sided structure. One side uses mold casting to create convex structures, while the other utilizes the evaporation of moisture during the curing process to form concave structures. At the same time, a novel side‐by‐side package structure is proposed, ensuring pressure on flexible substrate is maximally transferred to the GHBA microstructure. Within the range of 0.2 Pa–300 kPa, the iontronic pressure sensor achieves a maximum sensitivity of 10 420.8 kPa−1, pressure resolution of 0.1% under the pressure of 100 kPa, and rapid response/recovery time of 40/35 ms. In wearable devices, it is capable of monitoring dumbbell curl exercises and wirelessly correcting sitting positions. In electronic skin, it can non‐contactly detect the location of the wind source and achieve object classification prediction when combined with the CNN model.