bluuebunny/crossref_metadata_2025_split huggingface dataset:
Research progress in photodynamic therapy for Helicobacter pylori infection
Authors: Luo Qian , Liu Chunyan , Zhang Aiping , Zhang Dekui 
Published: March 2024

AbstractHelicobacter pylori (H. pylori) is a pathogenic microorganism that colonizes the human gastric mucosa and can lead to various gastric disorders, including gastritis, gastric ulcers, and gastric cancer. However, the increasing prevalence of antibiotic resistance in H. pylori has prompted the search for alternative treatment options. Photodynamic therapy has emerged as a potential alternative therapy, thus offering the advantage of avoiding some of the side effects associated with antibiotics and effectively targeting drug‐resistant strains. In the postantibiotic era, photodynamic therapy (PDT) has shown promise as a novel treatment for H. pylori infection. This review focused on elucidating the mechanism of photodynamic therapy in the treatment of H. pylori. Additionally, we present an overview of the current research on photodynamic therapy by examining both standalone photodynamic therapy and combination therapies for H. pylori infection treatment. Furthermore, the safety profile of photodynamic therapy was also evaluated. Finally, we discuss the challenges and prospects associated with this innovative technology, with an aim to provide new insights and methodologies for the treatment of H. pylori infection.
Electrothermal effect of carbon fiber and graphite reinforced metakaolin‐based geopolymer
Authors: Zhang Yajun , Lin Jialong , Chen Shikun , Ruan Shengqian , Wang Wenxin , Liu Yi , Yan Dongming 
Published: March 2024

AbstractThis paper investigates the influence of carbon fiber and graphite on the cyclic electrothermal performance of geopolymers (inorganic polymers). It was observed that carbon fibers, graphite, and the carbon fiber/graphite composite could form a stable conductive network at low voltage (3 V). However, under high voltages (9 and 12 V), the current of the geopolymer exhibited a peak shape in the first cycle, with higher voltages resulting in larger peak values and decreased conductivity in subsequent cycles. While graphite improved electrical and thermal conductivity, it weakened the microstructure, leading to an increase in microcracks and voids, and a reduction in the strength of geopolymers. The cumulative energy during the electrothermal process was calculated. The failure mechanism of the conductive network in the geopolymer during cyclic electrical heating was explained, highlighting the disruptive effect of gel shrinkage due to water loss on conductive networks.
Anesthesia nurses’ self‐perceived roles, competencies, and attitudes toward patient safety culture
Authors: Chang An‐Chi , Tsai Yun‐Fang 
Published: March 2024

AbstractAimThis study aimed to explore anesthesia nurses' (ANs) perceptions of roles, competencies, and attitudes towards patient safety culture, along with predictive factors for patient safety culture.IntroductionThe 2021 guidelines from the International Council of Nurses aim to ensure global access to safe surgical and anesthesia care by 2030. However, in Taiwan, the roles and competencies of ANs are still evolving. Many have a limited understanding, posing potential risks to patient safety.MethodsA cross‐sectional study was conducted, involving ANs from five hospitals within a healthcare foundation. ANs' self‐perceived roles and competencies were assessed using a structured questionnaire based on the CanMEDS framework from the International Federation of Nurse Anesthetists. Additionally, data were collected using the Chinese version of the Safety Attitudes Questionnaire. Reporting followed the STROBE guideline.ResultsAmong 200 ANs, a consensus emerged favored all roles and competencies, with positive attitudes toward patient safety culture. Remarkably, self‐perceived competencies, working in regional hospitals, and working in medical centers significantly predicted ANs’ attitude toward patient safety culture.DiscussionThe study results can assist ANs in gaining a deeper understanding of their roles and competencies. Considering predictive factors, strengthening ANs' competencies may contribute to enhancing patient safety culture.Conclusion and implication for nursing and health policyOur results informed nursing leaders and policymakers in Taiwan and other countries regarding ANs’ perceptions of roles and competencies. Nurse managers could consider the specific factors influencing ANs’ attitudes toward patient safety culture and make great efforts to develop strategies aimed at enhancing their competencies.
Stress as a mediator between abusive supervision and clinical nurses’ work outcomes
Authors: Labrague Leodoro J. 
Published: March 2024

AbstractAimsThis study aimed to test whether stress could mediate the association between abusive supervision and nurses’ work engagement, absenteeism, and turnover intention.BackgroundAbusive supervision has been attributed to suboptimal work performance and reduced productivity among employees in different sectors. While existing nursing literature links abusive supervision to a wide range of work‐related outcomes in the nursing workforce, little is known regarding the mechanism underlying this relationship.DesignData for this descriptive study were collected from 770 direct‐care nurses from seven acute care hospitals in the Philippines, utilizing five standardized scales.ResultsAbusive supervision had direct positive effects on absenteeism (β = .189, p < .001) and intent to leave (β = .138, p < .001) and a direct negative effect on job engagement (β = −.131, p < .001). The relationships between abusive supervision and absenteeism (β = .175, p < .001), intent to leave (β = .131, p < .001), and work engagement (β = −.122, p < .001) were partially mediated by stress.ConclusionsStress mediated the relationship between abusive supervision and nurses’ work outcomes, including turnover intention, absenteeism, and work disengagement.Implications for nursing and health policyThe evident connection between abusive supervision, stress, and work‐related outcomes underscores the importance of focusing on enhancing managerial supervisory styles as a potential organizational strategy to enhance staff retention and well‐being.
Risk of COVID‐19 Hospitalization and Protection Associated With mRNA Vaccination Among US Adults With Psychiatric Disorders
Authors: Levy Matthew E. , Yang Duck‐Hye , Dunne Margaret M. , Miley Kathleen , Irving Stephanie A. , Grannis Shaun J. , Weber Zachary A. , Griggs Eric P. , Spark Talia L. , Bassett Elizabeth , Embi Peter J. , Gaglani Manjusha , Natarajan Karthik , Valvi Nimish R. , Ong Toan C. , Naleway Allison L. , Stenehjem Edward , Klein Nicola P. , Link‐Gelles Ruth , DeSilva Malini B. , Kharbanda Anupam B. , Raiyani Chandni , Beaton Maura A. , Dixon Brian E. , Rao Suchitra , Dascomb Kristin , Patel Palak , Mamawala Mufaddal , Han Jungmi , Fadel William F. , Barron Michelle A. , Grisel Nancy , Dickerson Monica , Liao I‐Chia , Arndorfer Julie , Najdowski Morgan , Murthy Kempapura , Ray Caitlin , Tenforde Mark W. , Ball Sarah W. 
Published: March 2024

ABSTRACTBackgroundAlthough psychiatric disorders have been associated with reduced immune responses to other vaccines, it remains unknown whether they influence COVID‐19 vaccine effectiveness (VE). This study evaluated risk of COVID‐19 hospitalization and estimated mRNA VE stratified by psychiatric disorder status.MethodsIn a retrospective cohort analysis of the VISION Network in four US states, the rate of laboratory‐confirmed COVID‐19‐associated hospitalization between December 2021 and August 2022 was compared across psychiatric diagnoses and by monovalent mRNA COVID‐19 vaccination status using Cox proportional hazards regression.ResultsAmong 2,436,999 adults, 22.1% had ≥1 psychiatric disorder. The incidence of COVID‐19‐associated hospitalization was higher among patients with any versus no psychiatric disorder (394 vs. 156 per 100,000 person‐years, p < 0.001). Any psychiatric disorder (adjusted hazard ratio [aHR], 1.27; 95% CI, 1.18–1.37) and mood (aHR, 1.25; 95% CI, 1.15–1.36), anxiety (aHR, 1.33, 95% CI, 1.22–1.45), and psychotic (aHR, 1.41; 95% CI, 1.14–1.74) disorders were each significant independent predictors of hospitalization. Among patients with any psychiatric disorder, aHRs for the association between vaccination and hospitalization were 0.35 (95% CI, 0.25–0.49) after a recent second dose, 0.08 (95% CI, 0.06–0.11) after a recent third dose, and 0.33 (95% CI, 0.17–0.66) after a recent fourth dose, compared to unvaccinated patients. Corresponding VE estimates were 65%, 92%, and 67%, respectively, and were similar among patients with no psychiatric disorder (68%, 92%, and 79%).ConclusionPsychiatric disorders were associated with increased risk of COVID‐19‐associated hospitalization. However, mRNA vaccination provided similar protection regardless of psychiatric disorder status, highlighting its benefit for individuals with psychiatric disorders.
Simplified COVID‐19 guidance for adults with intellectual and developmental disabilities
Authors: Benson‐Goldberg Sofia , Geist Lori , Erickson Karen 
Published: March 2024

AbstractBackgroundDuring the COVID‐19 pandemic, the United States' Centers for Disease Control and Prevention (CDC) created guidance documents that were too complex to be read and understood by the majority of adults with intellectual and developmental disabilities who often read at or below a third‐grade reading level. This study explored the extent to which these adults could read and understand CDC documents simplified using Minimised Text Complexity Guidelines.MethodThis study involved 20 participants, 18–48 years of age. Participants read texts and responded to multiple‐choice items and open‐ended questions to gather information about how they interacted with and understood the texts.ResultsThe results provide initial evidence that the Minimised Text Complexity Guidelines resulted in texts that participants could read and understand.ConclusionImplications for increasing the accessibility of public health information so that it can be read and understood by adults with extremely low literacy skills are discussed.
Evolutionary causes of global patterns of species richness in regional fern floras across the world
Authors: Qian Hong , Kessler Michael , Zhang Jian , Jin Yi , Jiang Meichen 
Published: March 2024

AbstractAimGlobally, biodiversity is unevenly distributed, as a result of varying environmental conditions and regionally different historical processes. The influence of the latter on current diversity patterns is poorly understood. We explore geographic patterns of matches and mismatches between phylogenetic relatedness metrics measuring different depths of evolutionary history and investigate the effects of evolutionary legacy at different evolutionary depths on species density of ferns.MethodsWe divided the globe into 392 geographic regions on land, and collated species lists of ferns for each geographic region. We related species richness to phylogenetic metrics reflecting different depths of evolutionary history (standardized effect sizes of mean nearest taxon distance and mean pairwise distance, MNTDses and MPDses, respectively) for ferns in regional floras across the world.LocationGlobal.Time PeriodCurrent.TaxonFerns.ResultsWe show that different centers of fern diversity have strikingly different phylogenetic composition. We find that overall fern species diversity is negatively correlated with both MNTDses and MPDses, so that regions with high species diversity tend to have clustered species assemblages, whereas species‐poor regions tend to have overdispersed species assemblages. At the global extent, MNTDses and MPDses together explained 62.2%, 19.3%, and 65.7% of the variation in species diversity for all ferns as a whole, non‐polypod ferns, and polypods, respectively.Main ConclusionsOur study suggests that current geographic patterns of fern species richness are driven, at least in part, by evolutionary history of ferns, which varies among biogeographic regions.
New horizons in dermatological education: Skin cancer screening with virtual reality
Authors: Junga Anna , Schmidle Paul , Pielage Leon , Schulze Henriette , Hätscher Ole , Ständer Sonja , Marschall Bernhard , Braun Stephan Alexander ,   the medicaltr.AI.ning Consortium
Published: March 2024

AbstractBackgroundTechnological advances in the field of virtual reality (VR) offer new opportunities in many areas of life, including medical education. The University of Münster has been using VR scenarios in the education of medical students for several years, especially for situations that are difficult to reproduce in reality (e.g., brain death). Due to the consistently positive feedback from students, a dermatological VR scenario for skin cancer screening was developed.ObjectivesPresentation and first evaluation of the skin cancer screening VR scenario to determine to what extent the technical implementation of the scenario was evaluated overall by the students and how their subjective competence to perform a skin cancer screening changed over the course of the teaching unit (theory seminar, VR scenario, theoretical debriefing).MethodsStudents (n = 140) participating in the curricular pilot project during the 2023 summer term were surveyed throughout the teaching unit using several established questionnaires (System Usability Scale, Simulation Task‐Load‐Index, Realism and Presence Questionnaire) as well as additional questions on cybersickness and subjective learning.Results(i) The use of VR is technically feasible, (ii) students evaluate the VR scenario as a useful curricular supplement, and (iii) from the students' subjective perspective, a good learning outcome is achieved. Although preparation and follow‐up appear to be important for overall learning, the greatest increase in subjective competence to perform a skin cancer screening is achieved by the VR scenario.ConclusionsTechnically feasible and positively evaluated by students, VR can already be a useful addition to dermatology education, although costs are still high. As a visual discipline, dermatology offers special opportunities to create VR scenarios that are not always available or comfortable for patients in reality. Additionally, VR scenarios guarantee the same conditions for all students, which is essential for a high‐quality education.
Effect of glabridin combined with bakuchiol on UVB‐induced skin damage and its underlying mechanism: An experimental study
Authors: Peng Guanjie , Li Yangsi , Zeng Yiyan , Sun Bowen , Zhang Lanyue , Liu Qingqing 
Published: March 2024

AbstractBackgroundResearch has demonstrated the anti‐photoaging properties of glabridin and bakuchiol.MethodsThe impact of glabridin, glabridin + bakuchiol, and bakuchiol on the levels of tumor necrosis factor alpha (TNF‐α) and interleukin‐1 beta (IL‐1β) in mice skin fibroblasts was observed. Furthermore, we investigated the potential roles of fibronectin (FN), interferon‐γ (IFN‐γ), interleukin‐22 (IL‐22), and transforming growth factor‐β (TGF‐β) in the tissues, and evaluated their impact on the enzymatic levels in the skin. In conjunction with transcriptomic analysis, metabolomic profiling, and network pharmacology, all samples underwent comprehensive metabolomic and principal component analysis. The Venny2.1 method was utilized to identify variances in shared metabolites between the treatment group and the UVB group, as well as between the UVB group and the control group. Subsequently, a cluster heat map was generated to forecast and analyze metabolic pathways and targets.ResultsThe outcomes from the hematoxylin and eosin and toluidine blue staining revealed that glabridin and bakuchiol markedly decreased dermal thickness and suppressed mast cell infiltration in photoaged mice. Immunohistochemistry and Elisa analysis revealed that glabridin and bakuchiol effectively attenuated the levels of pro‐inflammatory factors, including IL‐1β, tumor necrosis factor‐α, IL‐22, and IFN‐γ. Furthermore, an increase in the levels of anti‐inflammatory factors such as FN and TGF‐β was also observed. The determination of the contents of superoxide dismutase, hydroxypropyltransferase and malondialdehyde in mice dorsal skin revealed that glabridin and bakuchiol not only elevated the levels of superoxide dismutase and hydroxyproline, but also reduced malondialdehyde content. Due to the limited number of shared differential metabolites exclusively within Kyoto Encyclopedia of Genes and Genomes, comprehensive pathway enrichment analysis was not feasible.ConclusionThis study demonstrates that glabridin and bakuchiol effectively impede photoaging and alleviate skin inflammation in mice.
Skin rejuvenation through topical application of indocyanine green with diffractive optical element mode of 785 nm picosecond laser in Asian females
Authors: Jung Dayeon , Seung Na Reu , Seo Suk Bae , Park Eun Joo , Kim Kwang Ho 
Published: March 2024

AbstractBackgroundIndocyanine green (ICG) exhibits robust absorption near 800 nm.AimsTo examine the clinical effects of combining ICG with a 785 nm picosecond laser for treating photo‐aged skin.Patient/MethodsA 785 nm 600 picosecond laser was used on the facial area of 16 female patients with Fitzpatrick skin type III and IV (mean age: 58.44 ± 5.24 years) after applying 0.0125% ICG cream. A total of 3000 shots were administered in diffractive optical element mode at a pulse energy of 200 mJ and frequency of 10 Hz. Hyperpigmented lesions were treated using the Zoom handpiece set at a spot size of 3–4 mm, pulse energy of 60–120 mJ, and frequency of 3–7 Hz. Patients underwent five sessions of treatment at intervals of 1–2 weeks. Wrinkles, pores and pigmented lesions were assessed at the initial assessment and 4 weeks after the final treatment using the Modified Fitzpatrick Wrinkle Scale and 10‐point visual analog scale, respectively. Skin biopsy of the postauricular area was performed on two consenting patients.ResultsSignificant improvements in wrinkles (p = 0.02), pores (p = 0.034), and hyperpigmentation (p = 0.036) were observed, along with increased patient subjective improvement. Adverse effects were transient and well‐tolerated. Hematoxylin and eosin and Masson's trichrome staining revealed increased and thickened dermal collagen fibers. Immunohistochemical staining revealed increased expression of collagen I and III throughout the papillary and upper reticular dermis, along with diffuse increase of STRO‐1 in the dermis.ConclusionsThe combined application of a 785 nm picosecond laser and ICG yielded promising clinical outcomes for treating photo‐aged skin in Asian patients with Fitzpatrick skin type III and IV.
Efficacy of isobutylamido thiazolyl resorcinol for prevention of laser‐induced post‐inflammatory hyperpigmentation: A randomized, controlled trial
Authors: Vachiramon Vasanop , Sakpuwadol Nawara , Yongpisarn Tanat , Anuntrangsee Tanaporn , Palakornkitti Pasita 
Published: March 2024

AbstractBackgroundQ‐switched (QS) Nd: YAG laser is one of the treatment options for solar lentigines (SLs). However, the incidence of post‐inflammatory hyperpigmentation (PIH) is a common complication, especially in dark‐complexioned skin. Isobutylamido thiazolyl resorcinol (ITR) has been reported as a preventive modality for ultraviolet B (UVB)‐induced hyperpigmentation.AimsThis study aims to evaluate the efficacy and safety of ITR for the prevention of laser‐induced PIH.Patients/MethodsA randomized, evaluator‐blinded study including 24 subjects with SLs was conducted. Three SLs of each patient were randomized into three groups, which were to apply ITR twice daily, once daily, and no application for 2 weeks. Thereafter, 532‐nm QS Nd: YAG laser was performed. Incidence of laser‐induced PIH, relative melanin index (RMI), mean luminance score (L*), hyperpigmentation score, and adverse events were recorded for 2 months post‐laser.ResultsThe incidence of PIH at the 4th week after laser treatment was significantly lower in the ITR twice‐daily group compared to the no‐application group (20.83% vs. 50%, p = 0.028). There was no statistically significant difference in RMI, mean L*, and hyperpigmentation score between treatments at all visits. No serious adverse events were reported regarding ITR application and laser treatment.ConclusionTwo‐week application of ITR prior to QS: Nd YAG laser treatment may potentially reduce the incidence of PIH. A longer duration of application, including after the laser procedure, may be more beneficial for the prevention of laser‐induced PIH.
Positional and conformist effects in voluntary public good provision
Authors: Cabo Francisco , Jean‐Marie Alain , Tidball Mabel 
Published: March 2024

AbstractThe literature featuring game–theoretical models aimed at explaining the effect of the status concerns on the voluntary provision of a public good is generally focused on snob agents, driven by a desire for exclusiveness. However, the social context literature highlights that status concerns can give rise to a desire, in some individuals to be different from the “common herd,” and in some others to conform with other people. We analyze a two‐player public good game under two different settings: The standard case with two positional players (PPs), versus the case in which the positional player faces a conformist player (PC). Giving entrance to conformism has two main implications. Strong status concerns by both players can lead to a virtuous cycle in which the conformist player wishes to imitate the contributing behavior of the positional player, and the latter wishes to increase contribution to distinguish herself from the former. Then, the contribution to the public good can be higher than in the case with only snob agents. This higher contribution can increase social welfare, but only if endowments are not too large and the status concern of the positional player is not excessively high.
Updated ACVIM consensus statement on equine herpesvirus‐1
Authors: Lunn David P. , Burgess Brandy A , Dorman David C. , Goehring Lutz S. , Gross Peggy , Osterrieder Klaus , Pusterla Nicola , Soboll Hussey Gisela 
Published: March 2024

AbstractEquine herpesvirus‐1 (EHV‐1) is a highly prevalent and frequently pathogenic infection of equids. The most serious clinical consequences of infection are abortion and equine herpesvirus myeloencephalopathy (EHM). The previous consensus statement was published in 2009 and considered pathogenesis, strain variation, epidemiology, diagnostic testing, vaccination, outbreak prevention and control, and treatment. A recent survey of American College of Veterinary Internal Medicine large animal diplomates identified the need for a revision to this original consensus statement. This updated consensus statement is underpinned by 4 systematic reviews that addressed key questions concerning vaccination, pharmaceutical treatment, pathogenesis, and diagnostic testing. Evidence for successful vaccination against, or effective treatment of EHV‐1 infection was limited, and improvements in experimental design and reporting of results are needed in future studies of this important disease. This consensus statement also updates the topics considered previously in 2009.