bluuebunny/crossref_metadata_2025_split huggingface dataset:
Flavoaffinins, elusive cellulose-binding natural products from an anaerobic bacterium
Authors: Kountz Duncan J. , Yu Ruocheng , Lee Jessie H. , Maloney Katherine N. , Balskus Emily P. 
Published: February 2025

ABSTRACTCellulose is the most abundant polymer on earth and plays a key role in the carbon cycle, agriculture, and human health. Many anaerobic cellulose-degrading bacteria produce uncharacterized yellow-orange, cellulose-binding pigments known as yellow affinity substances (here referred to as flavoaffinins) that are associated with efficient cellulose degradation. Here, we isolate and structurally characterize the flavoaffinins fromClostridium(Hungateiclostridium)thermocellum, a key workhorse for the industrial conversion of cellulosic feedstocks to ethanol. Flavoaffinins represent an unprecedented structural juxtaposition of an aryl polyene chain with a hydroxy-diene γ-lactone. We also shed light on their biosynthetic origins using stable-isotope feeding experiments. This effort lays the groundwork for understanding the biological function(s) of the flavoaffinins and expands the limited number of natural products isolated from obligately anaerobic microbes.Abstract Figure
Towards a tracking of bird migratory behaviour through geological time: an isotopic and histological approach
Authors: Duhamel Anaïs , Canoville Aurore , Vinçon-Laugier Arnaud , Joseph Julien , Fourel François , Lécuyer Christophe , Amiot Romain , Louchart Antoine 
Published: February 2025

AbstractBird seasonal migration is a remarkable biogeographic phenomenon, yet its deep-time origin(s) and evolutionary history remain poorly understood, with the bird fossil record largely overlooked. This study explores the predictability of bird migratory behaviour from the oxygen isotope composition of their bone apatite phosphate (δ18Op), a promising approach in this regard because: (i) sedentary and migratory birds tend to occupy distinct climatic niches year-round; (ii) their δ18Opvalues primarily reflect the climate-driven isotopic composition of their drinking water; and (iii) this isotopic signature can persist through fossilisation.Bone tissues were categorised based on their potential to yield spatio-temporally distinct climatic records: “early bone tissues” (EBT), deposited before somatic maturity, and “late bone tissues” (LBT), resulting from bone remodelling events over the lifespan. The predictability of migratory behaviour was theoretically assessed by modelling tissue-specific δ18Opvalues for thousands of birds across 77 migratory and sedentary species, based on their tracking or observational data, using a revised phosphate-water fractionation equation. These theoretical results were confronted with data from 11 extant bird species obtained using a new experimental framework that combines histological and isotopic analyses.We emphasised that, under specific sampling protocols, a significantly positive correlation between the δ18Opvalue and the proportion of LBT of bone samples is characteristic of long-distance migratory birds. Additionally, migratory birds that perished outside their natal sites can be identified when their δ18Op,EBTvalue falls outside the range observed in local juvenile and sedentary birds.We conclude that the migratory behaviour of birds can be inferred from the δ18Opvalues of their skeletal remains, with relatively low sensitivity (not all migratory behaviours are detected), but with high specificity (sedentary birds are rarely misclassified as migratory). We argue that the same method can be used to infer past bird migratory behaviours from well-preserved fossil bones, provided the palaeoclimatic context is carefully considered. More broadly, this study establishes a framework for inferring the migratory behaviour of any vertebrate from non-fully remodelled biomineralised remains.
Formalization or improvisation: the influence of team mindfulness on team resilience
Authors: Wang Yingli , He Qinghua , Xie Jianxun , Wang Zilun 
Published: February 2025

Purpose The increasing unexpected contingencies make resilience indispensable for project teams. Drawn on input–process–outcome (IPO) framework, this study aims to investigate how and when team mindfulness (i.e. input) fosters team resilience (i.e. outcome) via team formalization and team improvisation (i.e. process) under boundary conditions of the shared mental model.Design/methodology/approach By conducting a three-wave research design, this paper collects 312 questionaries from the Chinese construction industry. The proposed hypotheses were tested by hierarchical regression analysis and structural equation modeling.Findings The results confirm that team mindfulness exerts a positive effect on team resilience. The positive relationship is mediated by team formalization and team improvisation. In addition, the shared mental model serves as a buffering moderator between team mindfulness and team resilience via team improvisation.Practical implications This study suggests managers take appropriate interventions of mindfulness to foster team resilience. Making explicit procedures for risk management and taking improvisational action appropriately are also key processes for addressing crises.Originality/value This study enriches the literature on the positive prediction effect of team mindfulness on team resilience. Combining team formalization with team improvisation, this study provides new alternatives for the process variables in the IPO framework. Furthermore, this paper reveals the “dark side” of the shared mental model on the relationship between team mindfulness and team resilience.
Industry 4.0 in Africa: challenges and opportunities in the Moroccan and Nigerian automotive industries
Authors: Ojubanire Olugbenga Ayo , Marhraoui Mohamed Amine , Sebti Hicham , Berbain Sabrina 
Published: February 2025

Purpose
This study aims to explore the challenges and opportunities of adopting Industry 4.0 technologies in Africa, specifically focusing on the automotive industries in Morocco and Nigeria. By comparing these two leading African countries in Industry 4.0 adoption, the research seeks to identify key factors influencing the implementation of smart manufacturing technologies and to provide insights into the potential benefits and challenges faced.

Design/methodology/approach
The research uses a multiple case study design with a quantitative approach, collecting data through structured questionnaires from 167 participants across five automotive companies in Morocco and Nigeria. Regression analysis assessed the impact of opportunities and challenges. Statistical analysis identified significant differences between the two countries.

Findings
The study reveals significant differences in the perceived challenges and benefits of Industry 4.0 adoption between Morocco and Nigeria. In Morocco, key challenges include high implementation costs and resistance to change, whereas, in Nigeria, lack of skilled workforce and high implementation costs are predominant barriers. Both countries recognize the benefits of improved productivity, better product quality and enhanced supply chain agility.

Research limitations/implications
While focused on two countries and the automotive industry, the study provides valuable insights into Industry 4.0 adoption in Africa, with potential for expanded future research.

Practical implications
The insights provided by this study can guide policymakers in developing tailored strategies to support Industry 4.0 adoption in Africa. For organizations, understanding the specific challenges and benefits can aid in designing effective Industry 4.0 implementation plans, enhancing competitiveness and achieving sustainable growth.

Originality/value
By providing a comparative analysis of Morocco and Nigeria, the study offers unique insights into the specific factors influencing Industry 4.0 implementation in different African contexts with differences between North and West of Africa.
A hybridized Pythagorean fuzzy AHP and WASPAS method for airline new route selection: case study of Turkish Airline
Authors: Koma Şenay , Kusakci Ali Osman , Haji Amiri Misagh 
Published: February 2025

Purpose
This study aims to provide a practical and novel solution for the complex multi-criteria decision-making (MCDM) problem of airline route selection, which is characterized by conflicting criteria, alternative routes, and complex judgments.

Design/methodology/approach
This study proposes a hybrid MCDM approach using Interval-valued Pythagorean Fuzzy AHP and Interval-valued Pythagorean Fuzzy weighted aggregated sum product assessment (WASPAS) methods. Decision analysis is applied to select a new route between different alternatives through selection criteria. Pythagorean Fuzzy AHP is used for weighting criteria, and Pythagorean Fuzzy WASPAS is used for assessing alternatives. The pair-wise linguistic comparisons of selection criteria are transferred into Pythagorean fuzzy numbers (PFNs) to weigh each criterion’s importance.

Findings
The pair-wise linguistic comparisons of selection criteria are transferred into PFNs to weigh each criterion’s importance. The results of these comparisons show that the main criteria, cost (43% weight) and demand (33% weight), impact route selection decisions more than social/economic conditions (15% weight) and competitiveness (9% weight). Regarding the criteria, the five routes alternative were evaluated by the route development experts, and the best route was selected with Pythagorean Fuzzy WASPAS.

Practical implications
The proposed model is used for a route selection problem of Turkish Airlines, the airline that flies to the most countries in the world.

Originality/value
To the best of the authors’ knowledge, this study is the first to use the Interval-valued Pythagorean Fuzzy AHP combined with Interval-valued Pythagorean Fuzzy WASPAS to solve the route selection problem. This hybrid MCDM methodology presents a novel and feasible solution for selecting the new route for airlines.
Adverse childhood experiences, insecure attachment, and appointment compliance in an outpatient addiction psychiatry treatment population
Authors: Chambers Joanna E. , Perkins Susan M. , Mosesso Kelly M. , Ahdoot Azziza , Arnaudo Camila L. , Chambers R. Andrew 
Published: February 2025

AbstractBackground and ObjectivesSuffering adverse childhood experiences (ACEs) increases the probability of developing adult mental illness, addictions, and insecure attachment. This study determined how ACEs and insecure attachment are associated with each other, and how they may predict treatment engagement in an integrated dual diagnosis treatment clinic.MethodsA sample of n = 264 patients entering a university‐affiliated addiction psychiatry clinic underwent diagnostic intakes supplemented by assessments of attachment styles (Anxious/Avoidant, using the 36‐item Experiences in Close Relationships‐Relationship Structures (ECR‐RS) scale) and childhood adversity (10‐item Adverse Childhood Experiences Questionnaire (ACE‐Q) scale). Compliance with psychotherapy versus medication appointments was tracked for 6 months post intake.ResultsACE‐Q scores (median of 4) were significantly associated with higher anxious and avoidant attachment scores and the number of mental health diagnoses. Only one in five patients obtained 75% or higher compliance rates with psychotherapy; two in five achieved 75% or higher compliance with medication appointments. Greater anxious attachment predicted lower show rates for both psychotherapy and medication appointments, whereas greater avoidant attachment predicted lower compliance for psychotherapy only.Discussion and ConclusionsThis study confirms the linkage of ACEs and insecure attachment patterns in dual‐diagnosis patients seeking integrated addiction psychiatry care. Insecure attachment patterns differentially predicted lower appointment compliance, particularly for psychotherapies.Scientific SignificanceChildhood trauma and associated adult attachment dysfunction warrant further investigation not only as causes and correlates of mental illness and addiction but also for improving treatment engagement, therapeutic attachments, and recovery outcomes.
Trends in Proportions of Respiratory Syncytial Virus Infections Among Reported Respiratory Tract Infection Cases in Children Aged 0 to 5 Years in Western Pacific and Southeast Asia Regions: A Systematic Review and Meta‐Analysis
Authors: Park Sangshin , Lee Hyelan , Park Jung Yoon , Choi Sujin , Kim Hyun Jung , Bertizzolo Lorenzo , Lee Young Hwa , Choe Young June 
Published: February 2025

ABSTRACTBackgroundRespiratory syncytial virus (RSV) is an important cause of bronchiolitis and pneumonia in children globally. This study aimed to incorporate new data to update estimates of RSV burden in children through 5 years of age in Western Pacific and Southeast Asia Regions.MethodsA systematic review and meta‐analysis were conducted to examine the proportion of RSV among cases of respiratory tract infection (RTI) in children in Western Pacific and Southeast Asia Regions using random effects models. Studies were eligible if they met the following inclusion criteria: (1) observational studies such as cohort and cross‐sectional studies; (2) studies on humans; (3) studies on patients with RTI or influenza‐like illness (ILI); (4) studies reporting incidence or proportion of RSV infection among respiratory related illness; and (5) studies on children aged 5 years or less.FindingsA total of 4403 studies were identified from an initial search. After screening titles, abstracts, and full‐text review, a total of 173 studies that met predefined eligibility criteria were included in the analysis. The overall proportion of RSV infections among all ARTIs was 18.7% (95% CI: 16.0%–21.5%), whereas the proportion of RSV infections among LRTIs was 28.7% (95% CI: 2.6%–30.3%) in children in Western Pacific and Southeast Asia Regions between 1970 and 2020. The proportion of RSV infections peaked in the 1980s at 33.4% (95% CI: 19.8%–48.5%), having increased from 10.6% (95% CI: 2.9%–22.2%) in the 1970s. It then showed a decreasing trend, with 28.9% (95% CI: 18.8%–40.3%) in the 1990s, 24.5% (95% CI: 22.3%–26.8%) in the 2000s, and 20.1% (95% CI: 17.8%–22.5%) in the 2010s. By country, Myanmar (50.0%; 95% CI, 47.5%–52.4%) and New Zealand (45.3%; 95% CI, 37.1%–53.7%) had the highest proportion during the overall time period, followed by Bhutan (45.2%; 95% CI, 36.4%–54.3%), Lao PDR (41.0%; 95% CI, 36.2%–46.0%), and Vietnam (35.5%; 95% CI, 19.3%–53.6%).InterpretationSubstantial RSV‐associated disease burden occurs in children in Western Pacific and Southeast Asia Regions. Our findings provide new and important evidence of the need for RSV prevention in Western Pacific and Southeast Asia countries. They could inform future preventive policy.
Plasma membrane H+‐ATPase activation increases global transcript levels and promotes the shoot growth of light‐grown Arabidopsis seedlings
Authors: Kinoshita Satoru Naganawa , Taki Kyomi , Okamoto Fumika , Nomoto Mika , Takahashi Koji , Hayashi Yuki , Ohkanda Junko , Tada Yasuomi , Finkemeier Iris , Kinoshita Toshinori 
Published: February 2025

SUMMARYPlant cell growth requires the elongation of cells mediated by cell wall remodelling and turgor pressure changes. The plasma membrane (PM) H+‐ATPase facilitates both cell wall loosening and turgor pressure changes by acidifying the apoplast of cells, referred to as acid growth. The acid growth theory is mostly established on the auxin‐induced activation of PM H+‐ATPase in non‐photosynthetic tissues. However, how PM H+‐ATPase affects the growth in photosynthetic tissues of Arabidopsis remains unclear. Here, a combination of transcriptomics and cis‐regulatory element analysis was conducted to identify the impact of PM H+‐ATPase on global transcript levels and the molecular mechanism downstream of the PM H+‐ATPase. The PM H+‐ATPase activation increased transcript levels globally, especially cell wall modification‐related genes. The transcript level changes were in PM H+‐ATPase‐dependent manner. Involvement of Ca2+ was suggested as CAMTA motif was enriched in the promoter of PM H+‐ATPase‐induced genes and cytosolic Ca2+ elevated upon PM H+‐ATPase activation. PM H+‐ATPase activation in photosynthetic tissues promotes the expression of cell wall modification enzymes and shoot growth, adding a novel perspective of photosynthesis‐dependent PM H+‐ATPase activation in photosynthetic tissues to the acid growth theory that has primarily based on findings from non‐photosynthetic tissues.
Methanol Operation in Heavy-Duty DICI Dual-Fuel Engines: Investigating Charge Cooling Effects Using ECN Spray D Data
Authors: Zoumpourlos Konstantinos , Geertsma Rinze , Van De Ketterij Robert , Coraddu Andrea 
Published: February 2025

Abstract
Methanol is a promising alternative fuel, which can assist in reducing emissions in heavy-duty dual-fuel (DF) compression ignition (CI) engines. In medium and large bore marine engines, DF operation is achieved through either direct injection (DI) or port fuel injection (PFI) of methanol with diesel acting as a DI pilot fuel for ignition. However, the injection of methanol presents a significant challenge due to its high latent heat of vaporization and decreased lower heating value (LHV) compared to diesel. Therefore, for the same energy content operation, methanol requires around eight times the amount of heat to evaporate completely in comparison to diesel, which results in lower in-cylinder temperatures. This charge cooling effect leads to a strong negative temperature gradient influencing ignition and flame propagation. This paper aims to quantify the cooling effect of methanol in a heavy-duty dual-fuel DICI engine environment. The presented methodology uses Computational Fluid Dynamics (CFD) simulations to model methanol sprays with validation originating from the Engine Combustion Network (ECN) Spray D experimental data. The CFD models operate within the Lagrangian-Eulerian framework in CONVERGE-CFD using the Reynolds Averaged Navier Stokes turbulence modelling. Compared to diesel, injecting methanol with the same energy content exhibited up to 100 K more decreased temperature within the mixture. Consequently, this cooled mixture may pose challenges to combustion stability due to the intense temperature gradients. Nonetheless, lower mixture temperature decreases NOx emissions, which can prove beneficial for high methanol energy fractions in dual-fuel DICI engines.
Primary degradation assessment of 12Cr1MoVG steel by flat indentation and electron backscattered diffraction methods
Authors: Xu B , Zx Shen , Zhou Juan , Qian Sj , Cao Gm , Hu Chen , Lixun Cai 
Published: February 2025

Abstract
Most of the allowable design strain in high-temperature component occurs in the primary creep stage, so the accumulation of creep strain in this stage must be considered. Performance degradation of 12Cr1MoVG steel during interrupted creep test at 580°C and 110 MPa was assessed by the flat micro-indentation method, whereas the creep deformation and microstructural evolution due to primary creep were also evaluated by combination of scanning electron microscopy and electron backscattered diffraction. The energy density equivalent model established for flat indentation was introduced to evaluate the macro-mechanical properties of the 12Cr1MoVG at different creep times, the overall strain hardening behavior of has been attributed to microstructural degradation associated with precipitates, dislocation substructure and cavities nucleation. Based on the Larson-Miller parameter, an unusual softening behavior was also found during creep, significantly counteracting the strengthening and work hardening of the steel. Through examining the low-angle grain boundaries and dislocation density distributions, the sudden reduction in creep strength is the result of the dynamic recovery of substructure, which is linked to the rearrangement of dislocation structure into cells by glide and climb processes. It suggested that the flat indentation method is advantageous for micro-destructive assessment of early degradation of 12Cr1MoVG steel during the primary stage.
Recent developments in
Aspergillus fumigatus
research: diversity, drugs, and disease
Authors: Kordana Nicole , Johnson Angus , Quinn Katherine , Obar Joshua J. , Cramer Robert A. 
Published: February 2025

SUMMARY

Advances in modern medical therapies for many previously intractable human diseases have improved patient outcomes. However, successful disease treatment outcomes are often prevented due to invasive fungal infections caused by the environmental mold
Aspergillus fumigatus
. As contemporary antifungal therapies have not experienced the same robust advances as other medical therapies, defining mechanisms of
A. fumigatus
disease initiation and progression remains a critical research priority. To this end, the World Health Organization recently identified
A. fumigatus
as a research priority human fungal pathogen and the Centers for Disease Control has highlighted the emergence of triazole-resistant
A. fumigatus
isolates. The expansion in the diversity of host populations susceptible to aspergillosis and the complex and dynamic
A. fumigatus
genotypic and phenotypic diversity call for a reinvigorated assessment of aspergillosis pathobiological and drug-susceptibility mechanisms. Here, we summarize recent advancements in the field and discuss challenges in our understanding of
A. fumigatus
heterogeneity and its pathogenesis in diverse host populations.
Elliptic Boundary Layer in Shells of Revolution under Surface Shock Loading of Normal Type
Authors: Kirillova I. V. 
Published: February 2025

Abstract
In the present article, a method for solving a boundary value problem for an elliptical boundary layer occurring in thin-walled shells of revolution under normal-type impacts on the front surfaces is constructed. The elliptical boundary layer is constructed in the vicinity of a conditional front of Rayleigh surface waves and is described by elliptic equations with boundary conditions specified by hyperbolic equations. In the general case of shells of revolution, the methods for solving equations for an elliptical boundary layer developed for shells of revolution of zero Gaussian curvature cannot be used. The previously considered scheme for using the integral Laplace and Fourier transforms ceases to work since the resolving equations become equations with variable coefficients. The method for solving the equations of an elliptical boundary layer proposed in this paper is based on the use of an asymptotic representation of the images of the Laplace solution (in time) in exponential form. The paper presents a numerical calculation of the normal stress based on the obtained analytical solutions for the case of a spherical shell.
Probabilistic Degenerate Laguerre Polynomials with Random Variables
Authors: Luo L. , Ma Y. , Kim T. , Liu W. 
Published: February 2025

Abstract
In this paper, we define the probabilistic degenerate Laguerre polynomials associated with random variables and the probabilistic degenerate generalized Laguerre polynomials associated with random variables. We investigate some expressions, recurrence relations, and properties associated with the probabilistic degenerate Laguerre polynomials, the probabilistic degenerate generalized Laguerre polynomials, the probabilistic Lah numbers, and the partial Bell polynomials.

DOI 10.1134/S1061920824040095