bluuebunny/crossref_metadata_2025_split huggingface dataset:
Post molar choriocarcinoma with solitary renal metastasis in the absence of primary uterine tumor: a case report and review of the literature
Authors: Geravandi Mahsa , Hajihashemi Ali , Adibi Atoosa , Habibi Tirtashi Reza 
Published: March 2024

Abstract
Background
Choriocarcinoma is a rare and highly malignant form of gestational trophoblastic disease that may develop following pregnancy, abortion, or a hydatiform mole. Renal metastatic involvement by post molar choriocarcinoma is even rarer. In this case report, we describe a unique case of post molar choriocarcinoma with a solitary renal metastasis in the absence of a primary uterine tumor and metastases in other sites, which presented with urological symptoms and spontaneous renal hemorrhage.

Case presentation
A 41-year-old Persian woman with history of complete hydatiform mole presented with severe flank pain, nausea, vomiting, gross hematuria, and vaginal bleeding. Laboratory tests demonstrated a serum beta human chorionic gonadotropin hormone level of 60,000 mIU/mL. Imaging studies showed a lesion at the lower pole of the left kidney with active bleeding surrounded by hematoma, as well as an empty uterine cavity. Additionally, bilateral pleural effusion was detected without any lesion within the lungs. Subsequently, the patient underwent laparotomy, partial nephrectomy, and left para-ovarian cystectomy. Endometrial curettage was also carried out. The histopathology report revealed choriocarcinoma renal metastasis with high expression of beta human chorionic gonadotropin, cytokeratin 7, and Ki 67. Moreover, there were no malignant cells in the endometrial curettage specimens, and a corpus luteum cyst was found within the para-ovarian cyst. Further investigations revealed that the pleural effusion was free of malignant cells, and there was no evidence of metastatic lesions in the brain. As a result, the patient was referred to the oncology department to receive chemotherapy, and the beta human chorionic gonadotropin levels dropped to 5 mIU/mL after receiving courses of a standard regimen of etoposide, methotrexate, actinomycin D, cyclophosphamide, and vincristine/oncovin over 3 weeks. Finally, monthly measurements of beta human chorionic gonadotropin levels for 6 months indicated that levels have constantly remained within normal ranges, showing no evidence of recurrence or new metastasis.

Conclusions
Urological symptoms such as hematuria or spontaneous renal hemorrhage might be the only presentation of post molar choriocarcinoma with renal involvement. Thus, it can be beneficial to measure serum beta human chorionic gonadotropin levels among females of childbearing age who present with unexplained urological symptoms, especially if there is a history of prior hydatiform mole.
Low Mitotic Activity in Papillary Thyroid Cancer: A Marker for Aggressive Features and Recurrence
Authors: Lee-Saxton Yeon J , Egan Caitlin E , Bratton Brenden A , Thiesmeyer Jessica W , Greenberg Jacques A , Marshall Teagan E , Tumati Abhinay , Romero-Arenas Minerva , Beninato Toni , Zarnegar Rasa , Scognamiglio Theresa , Fahey Thomas J , Finnerty Brendan M 
Published: March 2024

Abstract

Context
The significance of low mitotic activity in papillary thyroid cancer (PTC) is largely undefined.

Objective
We aimed to determine the behavioral landscape of PTC with low mitotic activity compared with that of no and high mitotic activity.

Methods
A single-institution consecutive series of patients with PTC from 2018 to 2022 was reviewed. Mitotic activity was defined as no mitoses, low (1-2 mitoses/2 mm2) or high (≥3 mitoses/2 mm2) per the World Health Organization. The 2015 American Thyroid Association risk stratification was applied to the cohort, and clinicopathologic features were compared between groups. For patients with ≥6 months of follow-up, Cox regression analyses for recurrence were performed.

Results
A total of 640 PTCs were included—515 (80.5%) no mitotic activity, 110 (17.2%) low mitotic activity, and 15 (2.3%) high mitotic activity. Overall, low mitotic activity exhibited rates of clinicopathologic features including vascular invasion, gross extrathyroidal extension, and lymph node metastases in between those of no and high mitotic activity. PTCs with low mitotic activity had higher rates of intermediate- and high-risk American Thyroid Association (ATA) risk stratification compared with those with no mitotic activity (P &lt; .001). Low mitotic activity PTCs also had higher recurrence rates (15.5% vs 4.5%, P &lt; .001). Low mitotic activity was associated with recurrence, independent of the ATA risk stratification (HR 2.96; 95% CI 1.28-6.87, P = .01).

Conclusion
Low mitotic activity is relatively common in PTC and its behavior lies within a spectrum between no and high mitotic activity. Given its association with aggressive clinicopathologic features and recurrence, low mitotic activity should be considered when risk stratifying patients with PTC for recurrence.
Awareness and Willingness to Vaccinate against COVID-19 among Pregnant Women and Reasons Influencing their Decision in Poland – a Survey-Based Study
Authors: Baran Milena , Kuleta Martyna , Staniszewska Izabela , Mączyńska Wiktoria , Pater Mikołaj , Kazimierska Karolina 
Published: March 2024

Introduction: The COVID-19 pandemic has lasted for over 2 years and has resulted in more than 486 million cases and over 6 million deaths worldwide. Pregnant women are a special group of society exposed to severe or unpredictable course of infection.
Purpose of work: Assessment of awareness and willingness to vaccinate pregnant women against COVID-19 and reasons influencing this decision.
Materials and methods: The proprietary online survey addressed to women in Poland during pregnancy and women who were pregnant in the period from December 27, 2020 (introduction of the vaccine in Poland) to 20.03.2022. The study included a total of 518 respondents of reproductive age, among which 398 have a university degree and 108 have secondary education. 376 respondents got vaccinated against COVID-19 — 120 before getting pregnant, 199 during pregnancy and 57 after giving birth.
Summary: Most of the surveyed women (321) hadn’t had a positive PCR test for COVID-19 until the day of the survey, but 38% had a positive PCR test. Asked about reasons for getting vaccinated during pregnancy, most of the respondents stated that people should get vaccinated against COVID-19 in general, they got vaccinated because of the baby’s health, and that they acted according to the recommendations of The Polish Society of Gynecologists and Obstetricians and the World’s Health Organization. On the other hand, most of the women didn’t get vaccinated because they were afraid of the side effects, there is not enough research on the topic, and they believe that the vaccination is ineffective. Additionally, 154 respondents were encouraged by the doctors to get vaccinated in opposite to 21 who were discouraged by the doctor. The majority of the respondents are aware of the great risk of COVID-19 infection during pregnancy. Therefore, they got vaccinated against COVID-19 to minimize the risks of the infection.
Augmented reality: a new perspective in dental education
Authors: Blanchard Jessica , Koshal Sonita 
Published: March 2024

INTRODUCTION The Microsoft HoloLens is a mixed reality device with the capability to provide a real-time 3D platform using multiple sensors and holographic processing to display information, and even to simulate a virtual world. With rapidly evolving technology and virtual learning on the increase, the HoloLens can be used as a vital tool for education and surgical planning. The aim of this pilot study was to ascertain its benefit in dental education and in the surgical planning of complex oral surgery procedures. METHODS A cohort of postgraduate dentists working at the Eastman Dental Hospital in London were shown two holographic videos. Participation was voluntary and an email invitation was sent to all non-consultant grade dental staff across multiple dental specialties. The cases demonstrated were a mandibular third molar in close association with the inferior alveolar nerve and an impacted tooth. Each video had a narration and explanation by a consultant oral surgeon. After having watched the videos, participants were asked to rate seven statements using a Likert scale. RESULTS Eighty-two per cent of participants reported improved comprehension of orientating anatomical structures. All participants (100%) noted improved confidence in surgical planning. Ninety-four per cent believed that the technology was an invaluable surgical tool in postgraduate training. CONCLUSIONS Augmented reality has the potential to change the face of surgery in the 21st century. This technology can be used to improve surgical training, especially in an environment where hands-on training is limited and virtual learning is promoted.
Sol-Gel Spin Coated Transparent Single-TiO2 and SiO2 Thin Film on Glass for Opto-electronic Applications
Authors: Sigamani Saravanan , Someswararao M.V. , Swaminatham V. 
Published: March 2024

Great attention has been given on the sol-gel synthesis and spin-coating deposition techniques for the fabrication of various thin films. Because of its simple technique to fabricate dielectric (metal oxide) films using tetraethyl orthosilicate and titanium isopropoxide precursors. In this work, transparent single layer of SiO2 and TiO2 thin film was deposited on a glass substrate and characterized by FTIR, UV-visible spectroscopy, fluorescence and scanning electron microscopy techniques. The single layer thin film was mechanically stable and strong by adhering to glass substrates. The FTIR transmittance spectrum evidenced the existence of Si-O-Si and Ti-O-Ti at ~1100 and 1400 cm-1. The UV-visible absorbance spectra of single layer of SiO2 and TiO2 thin films showed strong absorption at below 00 nm. The excitation wavelength at 380 nm, the fluorescence spectra of both thin films showed the highest emission spectrum in between 733-798 nm. The SEM studies confirmed the smooth surface in both SiO2 and TiO2 layers. Further, it could be useful for various applications such as back reflector in solar cells, anti-reflection coatings, hydrophobic and anti-fogging materials.
A Case of Baker’s Cyst with Synovial Chondromatosis of Knee
Authors: Yashas Ullas Lokesh  , Anees Dudekula  , Revanth Ravindra Bhat  , Guru Yogendra Muthyala  , Doddala Vamsi Venkat  
Published: March 2024

Synovial chondromatosis is a benign condition which arises from synovial membrane or bursae around the joints. Joint abnormalities in the form of arthritic or mechanical conditions such as detachment of osseocartilaginous fragments from the articular surface are its secondary associations. Rarely there maybe involvement of the Baker’s cyst. Here we report a case in which a 60-year-old female came with complaints of pain, swelling and restriction of movement of right knee joint for the past one year. After careful clinical and radiological examination, it was diagnosed as Baker’s cyst complicated by synovial chondromatosis. After the diagnosis the patient underwent the following procedures: open synovectomy, cyst removal and thorough joint debridement. Synovial chondromatosis was confirmed histopathologically. Secondary synovial chondromatosis has features of osteoarthritic changes, lack of extensive synovial proliferation and complicated Baker's cyst which is not seen in primary synovial chondromatosis.
Synovial chondromatosis (SC) is caused by metaplasia of the synovium into chondrocytes and is a rare benign disorder.[1,2] Primary synovial chondromatosis (PSC) is a self-limited process that occurs in an otherwise normal joint.[3] When synovial chondromatosis develops in a joint previously affected with disease, often posttraumatic or degenerative osteoarthritis, it is called as secondary synovial chondromatosis.[4] SC may involve any joint, but the most common joint involved is knee joint followed by hip joint, and small joints of the hand and wrist. Least involvement is seen in elbow and shoulder joint. [5] The disease is categorised into three phases according to Milligram classification: active intrasynovial disease without any loose bodies observed in the early phase, active disease and loose bodies observed in the transitional phase, and multiple loose bodies without any intrasynovial disease observed in the late phase.
In orthopaedic practice, popliteal cysts are common occurrence; many of them are associated with degenerative or rheumatoid arthritis. The differential diagnoses become more complex when loose bodies and calcifications are noted within the joint on a radiograph. Here in, we are presenting a case of Baker’s cyst with synovial chondromatosis of knee treated by surgical excision and confirmed by histopathology.
ANALISIS FAKTOR RISIKO YANG MEMPENGARUHI KEJADIAN ANEMIA PADA PETANI DI DESA LINGGASARI KABUPATEN BANYUMAS
Authors: Radi Radi , Rejeki Dwi Sarwani Sri , Octaviana Devi 
Published: March 2024

Anemia is one of the non-communicable diseases that causes anemia sufferers to experience symptoms in the form of pallor, lethargy, dizziness or headache, and firefly eyes. The incidence of anemia worldwide is still high, it is estimated that as many as 1.3 billion people in the world suffer from anemia with a prevalence of 32.9% in 2018. Anemia in farmers is one of the health problems experienced by the residents of Linggasari Village, the incidence of anemia in farmers can be caused by various factors such as environmental factors and nutritional intake factors. The researcher intends to determine the risk factors for the incidence of anemia in farmers in Linggasari Village, Banyumas Regency. The purpose of this study was to analyze the influence of variables of education, income, length of service, history of pesticide exposure, use of PPE, nutrient intake, and helminthiasis on the incidence of anemia in farmers. This research method is quantitative research with a control case approach. The results of the analysis showed that the variable use of PPE was the most influencing factor in the incidence of anemia in farmers p value 0.023 OR 4.817 (1.247 – 18.605). Variables that do not affect the incidence of anemia in farmers are vairabel income p value 0.854, education p value 0.654, service period p value 0.608, nutrient intake p value 0.563, history of pesticide exposure p value 0.508, and disability p value 0.070).
Separating the Accountability and Competence Effects of Mayors on Municipal Spending
Authors: Boetti Lorenzo , Franzoni Federico , Galmarini Umberto , Piacenza Massimiliano , Turati Gilberto 
Published: March 2024

Abstract
The Italian legislation provides a two-term limits for mayors, but it allows term-limited mayors to pass on the torch to one of their deputies as candidates for mayorship. We exploit this feature of the electoral system to design a novel identification strategy for separating the effects of ‘accountability’ (the difference in performance between two politicians facing different incentives in terms of re-elections) and ‘competence’ (the difference in performance between two politicians with different experience in policy making). Using a panel of 1203 Italian municipalities, from 1998 to 2015, we find a significant role for competence but not for accountability in affecting municipal spending. Specifically, second-and-last-term mayors, and first-term mayors with previous experience as executive officers, spend less, on average, than inexperienced first-term mayors. We also discuss the policy implications of this finding.
Boomerang Entrepreneurs and the Declining Home City’s Place Image: Away on the Brain Drain Flow and Back on the Homesick Flow
Authors: Wilkerson James M. , Wafa Marwan A. 
Published: March 2024

Abstract

Boomerang entrepreneurs (practicing and nascent entrepreneurs who return to their declining home cities after years away) may especially be an answer to the brain drain, suppressed innovation, and often tepid entrepreneurial ecosystem condition that plague declining cities such as U.S. Rust Belt cities. This conceptual article addresses how the declining home city’s place image might inform and promote a boomerang entrepreneur’s return migration and venturing decisions and with what implications for the place’s entrepreneurial ecosystem. Even given homesickness, this kind of return migration is unlikely unless prospective boomerang entrepreneurs revise their place images of their old hometowns. We conceptually develop and support propositions on the relationships between place image and brain drain, between affect and both place image revision and entrepreneurial intentions, and between place image revision and both return migration intentions and entrepreneurial opportunity recognition. We also discuss implications for microfoundations of entrepreneurial ecosystems in declining cities, place branding that can encourage boomerang entrepreneurs’ place image revision and return migration to the declining home city, and related research data collection.
Potent antibacterial nanocomposites from okra mucilage/chitosan/silver nanoparticles for multidrug-resistant Salmonella Typhimurium eradication
Authors: El Rabey Haddad , Almassabi Rehab F. , Mohammed Ghena M. , Abbas Nasser H. , Bakry Nadia , Althiyabi Abdullah S. , Alshubayli Ibrahim H. , Tayel Ahmed A. 
Published: March 2024

Abstract
The polymeric nanocomposites (NCs), constructed from okra (Abelmoschus esculentus) fruits mucilage (OM), silver nanoparticles (AgNPs), and chitosan (Ch), were fabricated as potential candidates to overcome drug-resistant Salmonella Typhimurium bacteria. AgNPs were directly mediated by OM, with 4.2 nm mean diameters. The composed NCs from Ch/OM/AgNPs were innovatively synthesized and the various ratios of Ch:OM/AgNPs affected the NCs particles’ size and charges. The infrared analysis of employed materials/NCs validated their interactions and conjugations. The antibacterial assays of NCs against different resistant S. Typhimurium strains indicated the efficiency of polymeric NCs to inhibit bacteria with significant superiority over standard antibiotics. The NCs that contained equal ratios from Ch and OM/AgNPs were the best formulation (mean diameter, 47.19 nm and surface charge, +16.9 mV) to exhibit the strongest actions toward S. Typhimurium. The NCs caused severe deformation, destruction, and lysis in exposed bacteria, as traced with scanning microscopy. The biosynthesis of AgNPs using OM and their nanoconjugation with Ch provided effectual natural biopolymers NCs with enhanced expected biosafety and efficiency against drug-resistant S. Typhimurium strains, which supports their potential applications as disinfectant, sterilizing, and curative antibacterial agents.
Experimental investigation on the deterioration of the physical and mechanical properties of autoclaved aerated concrete at elevated temperatures
Authors: Tang Lingxiao , Yao Huayan , Zhang Mingyuan , Gan Jiarui , Xie Mingyu , Xie Wansheng 
Published: March 2024

Abstract
Autoclaved aerated concrete (AAC) has been extensively studied and applied in the past decades because of its excellent thermal insulation and acoustic performance, energy efficiency, and outstanding structural performance. To investigate the deterioration characteristics of AAC under high temperatures, the physico-mechanical properties of AAC at different temperatures were tested by mass loss, wave velocity, and compressive tests, and the deterioration mechanism was discussed by X-ray diffraction (XRD), thermogravimetric analysis (TGA), and scanning electron microscopy (SEM) tests. The results showed that after exposure to elevated temperatures, the parameters of apparent form, mass loss, wave velocity, and compressive strength underwent remarkable conversions. It was observed that the ultrasonic behavior of AAC was affected at high temperatures as it increased at 100°C and decreased beyond 100°C. In addition, the compressive strength exhibited a two-stage transformation, slightly increased from ambient temperature to 300°C, and exhibited a rapid reduction beyond 300°C. At 900°C, the specimen lost its strength. By XRD, TGA, and SEM, it was confirmed that a series of physicochemical changes in AAC, such as the water escape and evaporation, decomposition of calcium silicate hydrate and calcium carbonate, and structural damage, were the primary reasons for the deterioration of the physical and mechanical properties at elevated temperatures.
Sixth-kind Chebyshev polynomials technique to numerically treat the dissipative viscoelastic fluid flow in the rheology of Cattaneo–Christov model
Authors: Eid Ali , Khader Mohamed M. , Megahed Ahmed M. 
Published: March 2024

Abstract
This study investigates the complex dynamics of a viscoelastic fluid subjected to magneto-hydrodynamics over a stretching sheet, incorporating the Cattaneo–Christov heat flux model. This model is especially advantageous for explaining heat transfer in materials possessing significant thermal conductivity, where the conventional Fourier’s law might not be precise. The investigation revolves around evaluating how the thermal relaxation time affects the boundary layer and how both thermal radiation and viscous dissipation influence the thermal field. The significance of this research lies in its contribution to understanding the intricate behavior of such fluids in the presence of magnetic fields and non-Fourier heat conduction. The primary objective is to analyze the impact of viscoelasticity, magnetohydrodynamics, and Cattaneo–Christov heat flux on the flow and heat transfer characteristics over the stretching sheet. The research methodology involves the application of mathematical models and numerical techniques, particularly the use of the shifted Chebyshev polynomials of the sixth-order approximation and spectral collocation technique. The major conclusion of the study underscores the significant influence of viscoelasticity, magnetic field, and Cattaneo–Christov heat flux on the transport properties of the fluid, providing valuable insights for applications in various engineering and industrial contexts. Certain notable results arising from the current issue indicate that heat transfer is more pronounced for the viscoelastic factor and magnetic parameter, whereas the thermal relaxation parameter exhibits the opposite trend. In addition, the inclusion of the Cattaneo–Christov term enhances our comprehension of thermal behavior.
Bending energy absorption performance of composite fender piles with different winding angles
Authors: Chen Weisen , Fang Hai , Zhu Lu , Zhang Xinchen , Zhu Junyu 
Published: March 2024

Abstract
In recent years, there has been an increase in accidents involving vessels colliding with bridge piers. These ship–bridge collisions can result in tragic loss of life and severe damage to the bridge structure. To address this issue, a type of fender pile made of winding-formed glass fiber-reinforced polymer (GFRP) was proposed as a solution. In this article, three- and four-point bending tests were performed to compare and analyze the damage modes and load-carrying capacity of the fender piles at two different winding angles, namely 45° and 75°. Vertical impact test was simulated using ANSYS/LS-DYNA to verify finite element models. The results revealed variations in damage patterns and bending performance of GFRP piles under the two fiber winding angles. The simulation results suggest that GFRP fender piles can effectively increase the impact time of ship–bridge collisions and reduce the collision forces, thereby significantly improving the protection of bridge piers.