bluuebunny/crossref_metadata_2025_split huggingface dataset:
Blockade of interleukin 6 accelerates acinar cell apoptosis and attenuates experimental acute pancreatitis in vivo
Authors: Chao K C , Chao K F , Chuang C C , Liu S H 
Published: January 2006

Abstract

Background
It remains unclear whether interleukin (IL) 6 plays a role in initiating either the inflammatory or antiapoptotic responses in severe acute pancreatitis. This study examined the effect of neutralizing antibody against IL-6 on the induction of pancreatic acinar cell apoptosis and attenuation of the severity of severe acute pancreatitis.

Methods
Experiments were conducted on laboratory mice with severe acute pancreatitis induced by lipopolysaccharide injection following six injections of caerulein at intervals of 6 h. Neutralizing monoclonal anti-IL-6 antibody was administered either 5 min or 2 h after the first caerulein injection. Apoptosis in pancreatic sections was determined by the terminal deoxynucleotidyltransferase-mediated dUTP-biotin nick-end labelling method.

Results
Administration of caerulein and LPS induced an increase in serum amylase and IL-6 levels, severe acute pancreatitis, pancreatitis-associated lung injury, and phosphorylation of signal transducer and activator of transcription (STAT) 3 in the pancreas. A neutralizing antibody against IL-6 effectively suppressed these responses. Application of IL-6 neutralizing antibody caused the induction of apoptosis in the pancreatic acinar cells of mice with acute pancreatitis.

Conclusion
Blocking IL-6 suppresses STAT-3 activation in the pancreas and consequently attenuates the severity of severe acute pancreatitis by promotion of pancreatic acinar cell apoptosis.
Randomized clinical trial of the effect of preoperative dexamethasone on nausea and vomiting after laparoscopic cholecystectomy
Authors: Feo C V , Sortini D , Ragazzi R , De Palma M , Liboni A 
Published: January 2006

AbstractBackgroundPreoperative dexamethasone may reduce disabling symptoms such as pain, nausea and vomiting after laparoscopic cholecystectomy.MethodsThis was a randomized, double-blind, placebo-controlled trial. Between March and December 2004, 101 patients undergoing laparoscopic cholecystectomy were randomized to receive 8 mg dexamethasone (n = 49) or placebo (n = 52) intravenously before surgery. Six patients were excluded from the study. All patients received a standardized anaesthetic, surgical and multimodal analgesic treatment. The primary endpoints were: first, postoperative nausea, vomiting and pain; second, postoperative analgesic and antiemetic requirements. The pain scores (visual analogue and verbal response scales), the episodes of nausea (verbal response scale) and vomiting were recorded at 1, 3, 6 and 24 h, respectively, after the operation. Analgesic and antiemetic requirements were also recorded.ResultsNo apparent drug side-effects were noted. Seven patients (14 per cent) in the treatment group reported nausea and vomiting compared with 24 (46 per cent) in the control group (P = 0·001). In the group of patients treated with dexamethasone, five (10 per cent) required antiemetics versus 23 (44 per cent) of those receiving placebo (P &lt; 0·001). No difference in postoperative pain scores and analgesic requirements was detected between groups.ConclusionPreoperative dexamethasone reduces postoperative nausea and vomiting in patients undergoing laparoscopic cholecystectomy, with no side-effects, and may be recommended for routine use.
Skin-sparing mastectomy
Authors: Rainsbury R M 
Published: January 2006

Abstract

Background
Skin-sparing mastectomy (SSM) is a new technique being used in a variety of clinical settings. This article reviews the published data on SSM to establish its current role in clinical practice.

Methods
A Medline search was carried out using the key words ‘skin-sparing mastectomy’ to identify English-language articles published between 1990 and 2004 and further material referenced in these publications.

Results
SSM is most commonly used for surgical prophylaxis and to treat in situ and early invasive disease in patients who request immediate breast reconstruction. SSM and non-SSM result in similar surgical and oncological outcomes, but skin flap ischaemia is more common after SSM and is associated with a range of risk factors, including smoking.

Conclusion
SSM has become an established procedure in breast surgery, but there is a lack of prospective data on which to make evidence-based decisions about its use in individual patients.
Surveillance imaging for carotid in‐stent restenosis
Authors: Goldman Corey K. , Morshedi‐Meibodi Ali , White Christopher J. , Jaff Michael R. 
Published: January 2006

AbstractCarotid artery stent placement is the procedure of choice in suitable candidates who require carotid revascularization and are at increased risk for surgical therapy. To ensure late patency of the stent, continued surveillance is required. We present three cases to illustrate the strengths and weaknesses of noninvasive imaging techniques for surveillance of carotid stents, ultimately validated with invasive contrast angiography. © 2006 Wiley‐Liss, Inc.
Instant percutaneous closure of patent foramen ovale in patients with acute myocardial infarction and normal coronary arteries
Authors: Mehan Vivek K. , Wahl Andreas , Walpoth Nazan , Meier Bernhard 
Published: January 2006

AbstractTwo young women with angiographically normal coronary arteries suffered an acute myocardial infarction. Both were found to have a patent foramen ovale (PFO), the likely pathway of a paradoxical embolus causing the infarction. The PFOs were diagnosed and closed percutaneously with an Amplatzer PFO Occluder during the emergency coronary angiography. © 2006 Wiley‐Liss, Inc.
Comparison of sirolimus‐eluting stent, paclitaxel‐eluting stent, and bare metal stent in the treatment of long coronary lesions
Authors: Kim Young‐Hak , Park Seong‐Wook , Lee Cheol Whan , Hong Myeong‐Ki , Gwon Hyeon‐Cheol , Jang Yangsoo , Lee Myoung Mook , Koo Bon Kwon , Oh Dong Joo , Seung Ki Bae , Tahk Seung‐Jae , Yoon Junghan , Park Seung‐Jung 
Published: January 2006

AbstractObjective: This study compared the efficacy of the sirolimus‐eluting stent (SES), the paclitaxel‐eluting stent (PES), and the bare metal stent (BMS) for long coronary lesions. Background: The outcome of drug‐eluting stent (DES) implantation in long coronary lesions remains unclear. Methods: The study involved 527 patients with de novo long coronary lesions (≥24 mm), which were treated with long (≥28 mm) SESs (223 lesions), PESs (194 lesions), or BMSs (201 lesions). Results: Lesions in the SES (36.0 ± 14.9 mm, P < 0.001) and PES (36.3 ± 14.5 mm, P < 0.001) groups were longer than those in the BMS group (32.0 ± 12.3 mm), meaning the two DES groups had longer stented segments than did the BMS group. Six‐month angiographic follow‐up showed the SES (9.3%, P < 0.001) and PES (21.3%, P < 0.001) groups had lower in‐segment restenosis rates than that of the BMS group (42.5%). The rate of major adverse cardiac events (MACE) including death, myocardial infarction, and target lesion revascularization at 9 months was higher in the BMS group (26.6%) than that in the SES (13.0%, P < 0.001) and PES (15.7%, P < 0.001) groups. Posthoc analysis of the two DES groups showed that the in‐segment restenosis rate was lower for the SES than that for the PES group (P = 0.002), while the MACE rate was similar. Conclusions: The use of DESs for long coronary lesions appears to be safe and more effective than the use of BMSs in terms of restenosis and adverse clinical events. SES use was associated with lower late luminal loss and a lower angiographic restenosis rate compared with PES use. © 2006 Wiley‐Liss, Inc.
Renal artery angiography: “The right ipsilateral oblique” Myth
Authors: Bates Mark C. , Crotty Bradley , Kavasmaneck Cyrus , Campbell James R. 
Published: January 2006

AbstractBackground: Finding the optimal image intensifier angle of obliquity during renal intervention is important for accurate stent placement but can require multiple catheter rotations and test injections of contrast. Objective: Explore the usefulness of axial magnetic resonance angiography (MRA) as a roadmap for predicting image intensifier position during subsequent renal intervention. Methods: MRA images were reviewed in 137 consecutive patients (255 renal arteries) undergoing workup for renal artery stenosis. The axial angle of renal artery incidence perpendicular to the spine was estimated by two operators and results averaged. Results: The average angle of incidence for the renal artery ostia was +21.24° ±2.31° for the right and +8.81° ±2.0° for the left (P < .0001). The positive numbers correlate with left anterior oblique (LAO) and negative right anterior oblique (RAO). Conclusions: MRA can be used to define the origin of the renal artery and is most likely to predict an LAO image window for subsequent angiography of the left and right renal arteries displacing the “ipsilateral oblique” axiom. In patients without baseline MRA the 10 to 20 degree LAO “empiric” position will allow coaxial imaging of both renal ostia in 75% of cases. However, there can be extreme variation in the renal origin (53° RAO to 85° LAO) and we advocate using the simple technique reported herein to define the renal origin in patients with pre‐procedure MRA. © 2006 Wiley‐Liss, Inc.
Hyperuricemia as a risk factor for contrast‐induced nephropathy in patients with chronic kidney disease
Authors: Toprak Omer , Cirit Mustafa , Esi Ertap , Postaci Nursen , Yesil Murat , Bayata Serdar 
Published: January 2006

AbstractObjectives: Hyperuricemia as a risk factor for contrast‐induced nephropathy (CIN) has not been studied. Background: The aim of the present study was to assess the influence of hyperuricemia on the development of CIN in patients undergoing coronary angiography. Methods: This was a prospective cohort study. A total of 266 patients with a mean age of 58.33 ± 7.85 years and serum creatinine ≥1.2 mg/dl were divided into two groups (hyperuricemic, n = 126, and normouricemic, n = 140). CIN was defined as an increase of ≥25% in creatinine over baseline within 48 hr of angiography, and hyperuricemia as serum uric acid ≥7 mg/dl in males and ≥6.5 mg/dl in females. Results: CIN occurred in 15.1% of the hyperuricemic group and 2.9% of the normouricemic group (P < 0.001). Serum creatinine increased from 1.45 ± 0.20 to 1.67 ± 0.45 mg/dl in the hyperuricemic group and from 1.42 ± 0.16 to 1.56 ± 0.23 mg/dl in the normouricemic group (P < 0.001). Hyperuricemia [odds ratio (OR) 4.71; 95% confidence interval (95% CI) 1.29–17.21; P = 0.019] and a high incidence of multi‐vessel coronary involvement (OR 3.59; 95% CI 1.12–11.48; P = 0.032) in the hyperuricemic group were predictors of CIN. Hypoalbuminemia (P = 0.001) and age ≥70 years (P = 0.023) were other risk indicators of CIN. Length of hospital stay (P < 0.001) and CIN requiring renal replacement therapy (P = 0.017) were significantly higher in hyperuricemic group. Serum uric acid level ≥7 mg/dl in males and ≥5.9 mg/dl in females were found to be the best cut‐off value for prediction of CIN. Conclusion: Our data support the hypothesis that patients with hyperuricemia are at risk of developing CIN. © 2006 Wiley‐Liss, Inc.
Cyclic Quaternary Ammonium Ionic Liquids with Perfluoroalkyltrifluoroborates: Synthesis, Characterization, and Properties
Authors: Zhou Zhi‐Bin , Matsumoto Hajime , Tatsumi Kuniaki 
Published: January 2006

AbstractNew cyclic quaternary ammonium salts, composed of N‐alkyl(alkyl ether)‐N‐methylpyrrolidinium, ‐oxazolidinium, ‐piperidinium, or ‐morpholinium cations (alkyl=nC4H9, alkyl ether=CH3OCH2, CH3OCH2CH2) and a perfluoroalkyltrifluoroborate anion ([RFBF3]−, RF=CF3, C2F5, nC3F7, nC4F9), were synthesized and characterized. Most of these salts are liquids at room temperature. The key properties of these salts—phase transitions, thermal stability, density, viscosity, conductivity, and electrochemical windows—were measured and compared to those of their corresponding [BF4]− and [(CF3SO2)2N]− salts. The structural effect on all the above properties was intensively studied in terms of the identity of the cation and anion, variation of the side chain in the cation (i.e., alkyl versus alkyl ether), and change in the length of the perfluoroalkyl group (RF) in the [RFBF3]− ion. The reduction of Li+ ions and reoxidation of Li metal took place in pure N‐butyl‐N‐methylpyrrolidinium pentafluoroethyltrifluoroborate as the supporting electrolyte. Such comprehensive studies enhance the knowledge necessary to design and optimize ionic liquids for many applications, including electrolytes. Some of these new salts show desirable properties, including low melting points, high thermal stabilities, low viscosities, high conductivities, and wide electrochemical windows, and may thus be potential candidates for use as electrolytes in high‐energy storage devices. In addition, many salts are ionic plastic crystals.
Selective Heterogeneous Nucleation and Growth of Size‐Controlled Metal Nanoparticles on Carbon Nanotubes in Solution
Authors: Wang Yu , Xu Xin , Tian Zhongqun , Zong Ye , Cheng Huiming , Lin Changjian 
Published: January 2006

AbstractWe present a novel approach to the in situ deposition of size‐controlled platinum nanoparticles on the exterior walls of carbon nanotubes (CNTs). The reduction of metal ions in ethylene glycol (EG), by the addition of a salt such as sodium dodecyl sulfate (SDS), p‐CH3C6H4SO3Na, LiCF3SO3, or LiClO4, results in high dispersions and high loadings of platinum nanoparticles on CNTs without aggregation. We have performed controlled experiments to elucidate the mechanism. By exploiting the salt effect, our method effectively depresses homogeneous nucleation, leading to selective heterogeneous metal nucleation and growth, even on unmodified CNTs. In the 2.3–9.6 nm size range, the size of platinum nanoparticles, at 50 % loading, can be controlled by changing the concentration of metal ions, the reaction temperature, the reducing reagent or the means by which reactive solutions are added. Our method provides a flexible route towards the preparation of novel one‐dimensional hybrid materials, for which a number of promising applications in a variety of fields can be envisioned.
Donor‐Substituted 1,1,4,4‐Tetracyanobutadienes (TCBDs): New Chromophores with Efficient Intramolecular Charge‐Transfer Interactions by Atom‐Economic Synthesis
Authors: Michinobu Tsuyoshi , Boudon Corinne , Gisselbrecht Jean‐Paul , Seiler Paul , Frank Brian , Moonen Nicolle N. P. , Gross Maurice , Diederich François 
Published: January 2006

AbstractA wide variety of monomeric and oligomeric, donor‐substituted 1,1,4,4‐tetracyanobutadienes (TCBDs) have been synthesized by [2+2] cycloaddition between tetracyanoethylene (TNCE) and donor‐substituted alkynes, followed by electrocyclic ring opening of the initially formed cyclobutenes. Reaction yields are often nearly quantitative but can be affected by the electron‐donating power and steric demands of the alkyne substituents. The intramolecular charge‐transfer (CT) interactions between the donor and TCBD acceptor moieties were comprehensively investigated by X‐ray crystallography, electrochemistry, UV‐visible spectroscopy, and theoretical calculations. Despite the nonplanarity of the new chromophores, which have a substantial twist between the two dicyanovinyl planes, efficient intramolecular CT interactions are observed, and the crystal structures demonstrate a high quinoid character in strong donor substituents, such as N,N‐dimethylanilino (DMA) rings. The maxima of the CT bands shift bathochromically upon reduction of the amount of conjugative coupling between strong donor and acceptor moieties. Each TCBD moiety undergoes two reversible, one‐electron reduction steps. Thus, a tri‐TCBD derivative with a 1,3,5‐trisubstituted benzene core shows six reversible reduction steps within an exceptionally narrow potential range of 1.0 V. The first reduction potential Ered,1 is strongly influenced by the donor substitution: introduction of more donor moieties causes an increasingly twisted TCBD structure, a fact that results in the elevation of the LUMO level and, consequently, a more difficult first reduction. The potentials are also strongly influenced by the nature of the donor residues and the extent of donor–acceptor coupling. A careful comparison of electrochemical data and the correlation with UV‐visible spectra made it possible to estimate unknown physical parameters such as the Ered,1 of unsubstituted TCBD (−0.31 V vs Fc+/Fc) as well as the maxima of highly broadened CT bands. Donor‐substituted TCBDs are stable molecules and can be sublimed without decomposition. With their high third‐order optical nonlinearities, as revealed in preliminary measurements, they should become interesting chromophores for ultra‐thin film formation by vapor deposition techniques and have applications in opto‐electronic devices.
Palladium‐Catalyzed Reaction of Bicyclic Hydrazines with Allyl‐ and Arylstannanes in Ionic Liquid [bmim]PF6: A Facile Method for the Synthesis of Substituted Hydrazinocyclopentene Derivatives.
Authors: Radhakrishnan K. V. , Sajisha V. S. , Anas S. , Krishnan K. Syam 
Published: January 2006

AbstractFor Abstract see ChemInform Abstract in Full Text.
Single‐Step Preparation of a 4‐(Dimethylamino)pyridine Analogue Bearing a Sulfoxide as New Chiral Inducer. Preliminary Evaluation as Nucleophilic Catalyst.
Authors: Poisson Thomas , Penhoat Mael , Papamicael Cyril , Dupas Georges , Dalla Vincent , Marsais Francis , Levacher Vincent 
Published: January 2006

AbstractFor Abstract see ChemInform Abstract in Full Text.
Enantioselective Synthesis of the Optically Active α‐Methylene‐β‐hydroxy Esters, Equivalent Compounds to Morita—Baylis—Hillman Adducts, Using Successive Asymmetric Aldol Reaction and Oxidative Deselenization.
Authors: Shiina Isamu , Yamai Yu‐suke , Shimazaki Takahisa 
Published: January 2006

AbstractFor Abstract see ChemInform Abstract in Full Text.
A New Method for Synthesis of S‐Aryl‐O‐alkyl Thiolcarbonates: Selenium‐Catalyzed Reaction of Alcohols with Carbon Monoxide and Diaryl Disulfides.
Authors: Nishiyama Yutaka , Maehira Ken , Nakase Junko , Sonoda Noboru 
Published: January 2006

AbstractFor Abstract see ChemInform Abstract in Full Text.
A One‐Pot Preparation of Isothiocyanates from Amines Using Two Phosgene Substitutes: Bis‐(trichloromethyl) Carbonate and Trichloromethyl Chloroformates.
Authors: Bian Gaofeng , Shan Weiguang , Su Weike 
Published: January 2006

AbstractFor Abstract see ChemInform Abstract in Full Text.
t‐Bu‐Amphos—RhCl3×3H2O: A Highly Recyclable Catalyst System for the Cross‐Coupling of Aldehydes and Aryl‐ and Alkenylboronic Acids in Aqueous Solvents.
Authors: Huang Rongcai , Shaughnessy Kevin H. 
Published: January 2006

AbstractFor Abstract see ChemInform Abstract in Full Text.
Convenient Synthesis of 7,8‐Dimethoxytetralin‐2‐one.
Authors: Gorka A. , Czuczai B. , Szoleczky P. , Hazai L. , Szantay Cs. Jr. , Hada V. , Szantay Cs. 
Published: January 2006

AbstractFor Abstract see ChemInform Abstract in Full Text.
Novel (E)‐α‐[(1H‐Indol‐3‐yl)methylene]benzeneacetic Acids as Endothelin Receptor Ligands.
Authors: Pittala Valeria , Romeo Giuseppe , Materia Luisa , Salerno Loredana , Siracusa Maria Angela , Modica Maria , Mereghetti Ilario , Cagnotto Alfredo , Russo Filippo 
Published: January 2006

AbstractFor Abstract see ChemInform Abstract in Full Text.
Electrochemically Promoted C—N Bond Formation from Acetylenic Amines and CO2. Synthesis of 5‐Methylene‐1,3‐oxazolidin‐2‐ones.
Authors: Feroci Marta , Orsini Monica , Sotgiu Giovanni , Rossi Leucio , Inesi Achille 
Published: January 2006

AbstractFor Abstract see ChemInform Abstract in Full Text.
Lewis Acid Catalyzed Asymmetric Cycloadditions of Nitrones: α′‐Hydroxy Enones as Efficient Reaction Partners.
Authors: Palomo Claudio , Oiarbide Mikel , Arceo Elena , Garcia Jesus M. , Lopez Rosa , Gonzalez Alberto , Linden Anthony 
Published: January 2006

AbstractFor Abstract see ChemInform Abstract in Full Text.
New Cleavable Isocyanides for the Combinatorial Synthesis of α‐Amino Acid Analogue Tetrazoles.
Authors: Mayer Josef , Umkehrer Michael , Kalinski Cedric , Ross Guenther , Kolb Juergen , Burdack Christoph , Hiller Wolfgang 
Published: January 2006

AbstractFor Abstract see ChemInform Abstract in Full Text.
Investigations on Regio‐ and Stereoselectivities in Cycloadditions Involving α‐(3‐Pyridyl)‐N‐phenylnitrone: Development of an Efficient Route to Novel Nicotine Analogues.
Authors: Singh Gurpinder , Ishar M. P. S. , Girdhar Navdeep K. , Singh Lakhwinder 
Published: January 2006

AbstractFor Abstract see ChemInform Abstract in Full Text.
One‐Pot Synthesis of Novel N‐Cyclopropyldecahydroacridine‐1,8‐dione Derivatives under Microwave Irradiation.
Authors: Tu Shujiang , Zhang Xiaojing , Shi Feng , Li Tuanjie , Wang Qian , Zhu Xiaotong , Zhang Jinpeng , Xu Jianing 
Published: January 2006

AbstractFor Abstract see ChemInform Abstract in Full Text.
First Synthesis and X‐Ray Crystal Structure of Hexahydrobenzo[b]pyrido[3,4,5‐de]‐1,6‐naphthyridines.
Authors: Voskressensky Leonid G. , Borisova Tatiana N. , Listratova Anna , Vorobiev Ilia V. , Aleksandrov Grigory G. , Varlamov Alexey V. 
Published: January 2006

AbstractFor Abstract see ChemInform Abstract in Full Text.
A Modified, Economical and Efficient Synthesis of Variably Substituted Pyrazolo[4,3‐d]pyrimidin‐7‐ones.
Authors: Khan Khalid Mohammed , Maharvi Ghulam Murtaza , Choudhary Muhammad Igbal , Atta‐ur‐Rahman Atta‐ur‐Rahman , Perveen Shahnaz 
Published: January 2006

AbstractFor Abstract see ChemInform Abstract in Full Text.
Synthesis of Three Carbon Atom Bridged 2,4‐Diaminopyrrolo[2,3‐d]pyrimidines as Nonclassical Dihydrofolate Reductase Inhibitors.
Authors: Gangjee Aleem , Ye Zhengqu , Queener Sherry F. 
Published: January 2006

AbstractFor Abstract see ChemInform Abstract in Full Text.
2‐(2‐Furanyl)‐7‐phenyl[1,2,4]triazolo[1,5‐c]pyrimidin‐5‐amine Analogues: Highly Potent, Orally Active, Adenosine A2A Antagonists. Part 1.
Authors: Matasi Julius J. , Caldwell John P. , Zhang Hongtao , Fawzi Ahmad , Cohen‐Williams Mary E. , Varty Geoffrey B. , Tulshian Deen B. 
Published: January 2006

AbstractFor Abstract see ChemInform Abstract in Full Text.
Inhibition of Tumor Cell Proliferation by Thieno[2,3‐d]pyrimidin‐4(1H)‐one‐based Analogues.
Authors: Wang Yanong D. , Johnson Steven , Powell Dennis , McGinnis John P. , Miranda Miriam , Rabindran Sridhar K. 
Published: January 2006

AbstractFor Abstract see ChemInform Abstract in Full Text.
Synthesis of Some Pyrazolo[1,5‐c][1,3]benzoxazines and a New 5H‐Pyrazolo[1,5‐c][1,3,2]benzoxazaphosphorine Ring System
Authors: Svetlik Jan , Pronayova Nada , Kubista Jiri 
Published: January 2006

AbstractFor Abstract see ChemInform Abstract in Full Text.
A New Approach to 1‐Substituted‐1,2‐alkadienephosphonates. Part 2. Synthesis of 2‐Hydroxy‐3,4‐alkadiene‐3‐phosphonate Dimethyl Esters.
Authors: Enchev D. D. , Kirilov M. 
Published: January 2006

AbstractFor Abstract see ChemInform Abstract in Full Text.
Synthesis and Pharmacological Activity of Betulin Esters, Betulinic Acids and Allobetulin.
Authors: Flekhter O. B. , Medvedeva N. I. , Karachurina L. T. , Baltina L. A. , Galin F. Z. , Zarudii F. S. , Tolstikov G. A. 
Published: January 2006

AbstractFor Abstract see ChemInform Abstract in Full Text.
Active Secondary Metabolites from Fungi. Part 22. New Oblongolides Isolated from the Endophytic Fungus Phomopsis sp. from Melilotus dentata from the Shores of the Baltic Sea.
Authors: Dai Jingqiu , Krohn Karsten , Gehle Dietmar , Kock Ines , Floerke Ulrich , Aust Hans‐Juergen , Draeger Siegfried , Schulz Barbara , Rheinheimer Joachim 
Published: January 2006

AbstractFor Abstract see ChemInform Abstract in Full Text.
Synthesis of 5‐Haloethynyl‐ and 5‐(1,2‐Dihalo)vinyluracil Nucleosides: Antiviral Activity and Cellular Toxicity.
Authors: Escuret Vanessa , Aucagne Vincent , Joubert Nicolas , Durantel David , Rapp Kimberly L. , Schinazi Raymond F. , Zoulim Fabien , Agrofoglio Luigi A. 
Published: January 2006

AbstractFor Abstract see ChemInform Abstract in Full Text.