bluuebunny/crossref_metadata_2025_split huggingface dataset:
Correlation Between TG/HDL-C Ratio or Triglyceride-Glucose Index and Mean Arterial Pressure in Patients with Myocardial Infarction: A Correlative Analytical Study
Authors: Cheng Lele , Bian Yitong , Meng Zixuan , Jin Ping 
Published: March 2024

Abstract
Background: Triglyceride to high-density lipoprotein cholesterol (TG/HDL-C) ratio and the triglyceride-glucose (TyG) index have become novel and convenient indicators of insulin resistance (IR) and are reported to be associated with occurrence and prognosis of myocardial infarction (MI). Mean arterial pressure (MAP) is another MI indicator that affects myocardial perfusion and oxygen delivery. However, the association between TG/HDL-C ratio and TyG index with MAP in patients with MI remains unclear. The purpose of this study was to explore the correlation between TG/HDL-C ratio and TyG index with MAP in patients with MI, so as to provide new strategies to improve the prognosis of MI.
Method: A total of 7341 patients with MI from January 2019 to December 2020 were enrolled to collect the general clinical data. The subjects were divided into four groups based on the quartiles of TG/HDL-C ratio and TyG index respectively. Spearman correlation analysis, univariate and multivariate linear regression analysis were employed to examine the correlation between TG/HDL-C ratio and TyG index with MAP.
Results: The average age of the 7341 patients with MI was 61.39±13.13, and 62.23% were male. Spearman linear correlation analysis showed that MAP was positively associated with TG/HDL-C ratio (r=0.1218, p<0.001) and TyG index (r=0.1197, p<0.001). Univariate regression analysis showed that TG/HDL-C ratio and TyG index were positively associated with MAP in the participants. Each one unit increase in the TG/HDL-C ratio and TyG index was response for a 0.90 and 0.29 mmHg increase in MAP. Multiple regression analyses showed that MAP in the Q2, Q3 and Q4 group of the TG/HDL-C ratio were higher than those in the Q1 group (Q2 vs. Q1: β =1.42, 95%CI: 0.16-2.67; Q3 vs. Q1: β=2.04, 95%CI: 0.78-3.30; Q4 vs. Q1: β=2.55, 95%CI: 1.26-3.85). Similarly, MAP increased 1.99 mmHg in Q4 group of the TyG index when compared with the Q1 group (Q4 vs. Q1: β=1.99, 95%CI: 0.57-3.42). The association of the TyG index with MAP were more significant in male patients than in females (β=0.25 vs 0.007, p for interaction=0.023).
Conclusion The TG/HDL-C ratio and TyG index were significantly positively associated with MAP in MI patients, and the association between the TyG index with MAP was more significant in male patients. Monitoring the TG/HDL-C ratio and TyG index and assessing the association between the two with MAP deserves more attention in clinical practice for the early prevention and prognosis of MI and cardiometabolic diseases.
Multi-scale hierarchical brain regions detect individual and inter-species variations of structural connectivity in macaque monkeys and humans
Authors: Ouchi Kazuya , Yoshimaru Daisuke , Takemura Aya , Yamamoto Shinya , Hayashi Ryusuke , Higo Noriyuki , Obara Makoto , Sugase-Miyamoto Yasuko , Tsurugizawa Tomokazu 
Published: March 2024

Abstract

Macaques are representative animal models in translational research. However, the distinct shape and location of the brain regions between macaques and humans prevents us from comparing the brain structure directly. Here, we calculated structural connectivity (SC) with multi-scale hierarchical regions of interest (ROIs) to parcel out human and macaque brain into 4 (level 1 ROIs) or 13 (level 2 ROIs) regions, which consist of anatomically and functionally defined level 3 ROIs (around 100 parcellation of the brain) and similar function. The SC with the level 1 ROIs showed lower individual and inter-species variation in macaques and humans. SC with level 2 ROIs shows that the temporal lobe has high individual and inter-species variation in macaques and humans, while the prefrontal and sensory cortices show low individual and inter-species variation. These results provide insights into the suitability of macaques as animal models for humans.
Prevalence of Undiagnosed Hypertension and its Associated Factors in Ndera Sector, Gasabo District of Rwanda: A Cross-Sectional Study
Authors: Okesina Akeem Ayodeji , Habineza Jean Claude , Mbazumutima Richard , Mignonne Umurerwa , Mahirwe Celine , Hakizimana Samuel , Gbadamosi Mojeed Akorede , Uppal Aashna , Wabwire Francis Paul 
Published: March 2024

Abstract

Background
Hypertension remains a significant global health challenge, especially in low- and middle-income countries. It affects millions worldwide, with nearly half of the cases left undiagnosed. In Rwanda, a lack of adequate information and healthcare services impacts healthcare-seeking behaviours, contributing to undiagnosed hypertension in rural areas. Therefore, there exists a need to determine the incidence of undiagnosed hypertension and its associated factors.
Methods
A cross-sectional study of 393 adults was conducted in Ndera Sector, in Rwanda's Gasabo District, through a multistage sampling technique. Data was gathered using the WHO STEP-wise approach to non-communicable disease risk factor surveillance (STEPS) questionnaire; physical examination was done for blood pressure and body-mass index (BMI), after which the data collected were analyzed using SPSS.
Results
In Ndera Sector, 15% of the sample population had undiagnosed hypertension. Survey respondents had a mean age of 37 years (range 15 to 82), and 43% were male. Physical activity levels varied, with 41% reporting regular activity, and 59% reporting a lack thereof. Significant factors associated with undiagnosed hypertension (p value < 0.05) included age categories 45–54 years and ≥ 55 years, residing in Kibenga Cell, and having a BMI greater than 25.0 kg/m2. Bivariate analysis revealed significant associations of undiagnosed hypertension with age (≥ 55), having a BMI greater than 30.0 kg/m2 (obesity), and location of residence. The knowledge gap on hypertension also emerged as a significant factor, with those lacking awareness displaying a higher prevalence of undiagnosed hypertension. Sex, marital status, and other lifestyle habits showed no significant associations with undiagnosed hypertension.
Conclusions
High prevalence of undiagnosed hypertension in Ndera Sector was found to be associated with older age, high BMI, location of residence, and a lack of knowledge related to hypertension. This underscores the importance of health education initiatives, targeted healthcare initiatives in specific areas, tailored healthcare strategies for older age groups, and weight management initiatives to enhance awareness and early detection of hypertension.
Finch-Skea dark energy star with anisotropy
Authors: Das Bibhash , Aktar Somi , Rahaman Farook , Paul Bikash Chandra 
Published: March 2024

Abstract

We present relativistic model of anisotropic compact objects with spherically symmetric matter distribution coupled with dark energy in the framework of general theory of relativity. We assumed an ansatz for dark energy (DE) equation of state in addition to the baryonic matter. The interior spacetime of the compact object is described by the Finch-Skea metric and a causal domain of DE with a coupling parameter β. The stellar model is employed to investigate physical features energy-density, radial pressure, transverse pressure, energy conditions, mass-radius relation for a given pulsar, PSR J0348+0432 (M = 2.01 ± 0.04 M⊙ and R = 12.072 km). The effect of DE is explored for different values of β. We test the stability of the stellar models for different values of DE coupling parameter β for a relativistic stellar model. The equation of state of the matter configuration inside the star is determined for different β and found nonlinear. The prescription for a realistic stellar model used for the given pulsar is employed for other pulsars. The equation of states for those pulsars and the model parameters are determined for the observed masses and radii of the pulsars. The EoS is non-linear and the plot of mass vrs. radius of the stellar models considered here predict that the maximum mass of a star is independent of the DE coupling parameter (β).
Prevalence and influencing factors of myopia in children: a school-based cross-sectional study in Sanya, China
Authors: Fang Cheng , Qiu Ting , Zheng Huijia , Jiao Yao , Wei Hui , Liu Shijian , Wang Xiaoyan , Liu Hong 
Published: March 2024

Abstract

Background: Sanya is the southernmost city in China and has long sunshine duration and strong ultraviolet radiation intensity. The prevalence of myopia among schoolchildren in Sanya has not yet been reported.
Methods: This was a cross-sectional study in Sanya conducted by random cluster sampling from November to December 2022. This school-based study included 8 preschools, 8 primary schools and 8 secondary schools.
Students in the senior class of kindergarten (preschool), grade 3 (primary school) or grade 7 (secondary school), with or without myopia were enrolled. All the schools in each of the districts in Sanya were randomly chosen.
Results: A total of 4074 students were enrolled, and the prevalence of myopia was 28.0%. The prevalence of myopia significantly increased with educational stage: 2.8% in preschools, 21.4% in primary schools and 50.1% in secondary schools. Logistic regression analysis revealed that higher education level (odds ratio (OR)=1.513, 95% CI=1.460-1.567), female sex (OR=1.426, 95% CI=1.220-1.666), one-parent myopia (OR=2.085, 95% CI=1.733-2.509), both parents’ myopia (OR=2.800, 95% CI=2.100-3.734) and outdoor time >2 h (OR=0.720, 95% CI=0.623-0.851) were significantly related to myopia.
Conclusions: Due to its unique environmental conditions, the incidence of myopia among school-age children in Sanya was lower than that in most cities in China. Education and the environment were the two main factors affecting school myopia, and education seemed to play a more important role.
Research on the group path of enhancing the efficiency of public sports services in China - Based on DEA and fsQCA analysis
Authors: Han Xue , Zou Yuehui , Meng xiangyang 
Published: March 2024

Abstract

Background
Public sports services crucially affect the development of a healthy China as a robust sports country, and the improvement of public sports service efficiency is a crucial manifestation of its high-quality development.
Materials and methods
We utilize the data of 30 provinces in China in 2020 as the research object, and we utilize Data Envelopment Analysis (DEA) to measure and evaluate the efficiency level of China's public sports services as well as Fuzzy Set Qualitative Comparative Analysis (fsQCA) to identify the critical influencing factors; moreover, we explore the grouping path that affects the efficiency improvement of public sports services.
Results
The results indicate the following: 1) although the efficiency level of China's public sports services is high overall, there are significant differences among regions. 2) The level of regional GDP per capita, the strength of government support, and the number of years of education per capita are the critical influencing factors for enhancing the efficiency of public sports services. 3) Population-intensive and government-driven, economic vitality and resource-inputting, and economic-educational double-driven paths are the core paths enhancing the efficiency of China's public sports services.
Conclusion
Therefore, the following recommendation is made: to boost the efficiency of China's public sports services by focusing on the level of regional economic development and rationally allocating public sports resources; increasing the investment of public sports funds to enhance the quality and level of services; strengthening the government's purchasing efforts to promote the market-based operation of public sports services; and increasing the average years of education to strengthen the public's awareness and participation in sports.
The Relationship Between Sphenoidal Sinus and Sella Turcica Morphometry in the Turkish Population: A Retrospective Study
Authors: KELEŞ Hacı , YAKAR Hüseyin , KAYA İsmail , ÇİÇEK Fatih , CERANOĞLU Faruk Gazi , ÇİFTÇİ Ali Türker , KARADAĞ Hüseyin 
Published: March 2024

Abstract

Purpose
The anatomical position of the sphenoidal sinus (SS) is very important for neurosurgeons because of the transsphenoidal approach to the pituitary gland. Therefore, the aim of this study was to determine the volume and shape of the SS and its relationship with the morphometry of the sella turcica.
Methods
This study included CT images of 282 males and 258 females with a mean age of 50.52 years (range 18–75) who underwent head CT. The morphometric values of the sella turcica and the volume of the SS were measured on the included radiologic images. Measurements were made on the sagittal slice closest to the midline in T1 sequence. Morphometric measurements were made with Micro Dicom Viewers software program and volume measurements were made with ITK SNAP software program.
Results
In this study, 4 types of SS shapes were obtained in the whole population: amorphous, pentagonal, triangular and quadrilateral. The mean SS volume was 7055.88 mm3 in males and 5694.48 mm3 in females and a statistically significant difference was observed (p < 0.001). In addition, a statistically significant difference was found between the sexes in the width and surface area parameters of the sella turcica (p < 0.05).
Conclusion
In conclusion, surgeons who want to access the pituitary gland and its vicinity via the transsphenoidal route should know the anatomy of the region, the variations in the region and the relationship of the SS with the surrounding structures. We believe that the information presented in our study will guide the surgeons in their interventions.
Rates of Trauma Exposure, Posttraumatic Stress Disorder (PTSD), Depressive, and Anxiety Symptoms in Primary School Children: Findings Six Months before Covid-19 Pandemic
Authors: Ghazali Siti Raudzah , Chen Yoke Yong , Elklit Ask , Rehman Sana , Ang Ai Ling 
Published: March 2024

Abstract
Studies on mental health rates among primary school children are still limited particularly related to psychological trauma and its relationship to other mental health challenges. This is the first cross-sectional study examining the rates of trauma exposure, posttraumatic stress disorder (PTSD), depressive, and anxiety symptoms in primary school children before covid-19 pandemic in Malaysia. Two hundred and twenty-one students participated in this study. They were recruited from four primary schools that volunteered to participate in the study. PTSD) Checklist for DSM-5 (PCL-5), Child PTSD Symptoms Scale-5 (CPSS-5), The Center for Epidemiologic Studies Depression Scale version (CESD) and the Spence Children's Anxiety Scale (SCAS) were used to survey psychological symptoms. Most of the students, or 54.3% of them, have experienced at least one traumatic event. Of 221 students, 39.4% reported having PTSD symptoms, 38% reported having depressive symptoms and 19% reported having anxiety symptoms. Female students were more likely to report PTSD symptoms compared to male students. The first regression analysis model showed that only depressive symptoms were significant predictors for PTSD. In the second model, religion, family income, anxiety and PTSD symptoms were significant predictors of depressive symptoms. In the third model, only depressive symptoms were significant predictors of anxiety. Findings, limitations, research future directions and recommendations were discussed.
Acute Interstitial Nephritis and Tubular Necrosis after Lamotrigine-overdose: Characterization of Acute Kidney Failure in Lamotrigine-induced DRESS-syndrome
Authors: Brüning Klara Kristin , Pelivan Elena , Heinrich Marie-Christine , Bufler Philip , Kaindl Angela Maria , Thumfart Julia 
Published: March 2024

Abstract
We present a case of lamotrigine-triggered DRESS (drug reaction with eosinophilia and systemic symptoms)-syndrome with acute kidney injury stage 3. A 17-year-old girl with known epilepsy treated with lamotrigine presented with acute kidney injury as well as skin eruption, fever, and apathy. Extended diagnostics, considering infectious and autoimmune diseases, remained unremarkable. Lamotrigine blood levels were within the target range. Kidney biopsy showed acute interstitial nephritis with tubular necrosis. Methylprednisolone pulse therapy led to an improvement in kidney function; skin eruption and neurological symptoms disappeared. During the hospital stay, the girl admitted to inconsistent and variable intake of lamotrigine, occasionally resulting in notable overdosing. This report demonstrates that acute kidney injury in lamotrigine-induced DRESS-syndrome is an acute interstitial nephritis with tubular necrosis, an aspect that has not been deeply characterized so far. Additionally, we want to heighten awareness towards non-adherence as cause of disease, especially among the adolescent population.
Comparison of Cost and Energy Efficiency of Prefabricated Residential Modules with Various Construction Material Combinations
Authors: Bhayani Mohit , P Adithya Kamath , B Raghavendra Holla , Jathan Lekhan B , Bansal Aniket 
Published: March 2024

Abstract

Prefabricated housing has been in existence for over a century, but their recent rise in popularity can be attributed to advancements in technology and sustainable practices. The main aim of this study is to develop and design low-cost housing using eco-friendly and prefabricated materials which are suitable for Indian climate. Space optimization techniques were used to design the housing unit and achieved compact carpet area compared to average space of these houses. Cost-effective materials such as Aerocon wall panels and Calcium Silicate wall panels, and Eco-friendly materials such as Expanded Polystyrene (EPS) panels were selected. By incorporating these materials, the cost analysis was carried out under economic and energy efficient considerations. the comparison of the cost shows even through initial investment is more for the energy efficient material, it proves cheaper to lifecycle cost. This provides opportunities for the government to provide mass housing schemes and efficient houses, but it contains certain disadvantages such as high initial cost and thermal bridging or cracking of sandwich panels. Finally, as per the study it encourages further research focused on Implementation of Energy-Efficient systems and advancements in sustainable materials to further enhance the environmental performance and sustainability of Prefabricated houses.
Research on Modern Architecture Culture of Harbin based on Memes
Authors: Cai Jun , Dong Jianfei , Zhou Yuan 
Published: March 2024

Abstract

Cultural meme, which have the same heritability and variability as particulate biological genes, provides culture units that can be shared and transmitted across different periods, allowing cultural computing to be made in a fine-grained manner. This paper extracts regional architectural cultural memes from the basic information of Harbin city's modern architectural heritage, and constructs the urban historical architectural cultural memes matrix. By using the social network calculation method, we analyse the representative architectural meme such as material meme, structural system meme, architectural style meme, etc., which represent the evolution of urban architectural culture, construct a network of urban architectural cultural memes, and explore its clustering characteristics and centrality characteristics. The research shows that Harbin urban architectural culture in the development and evolution of the process has a holistic cultural characterisation beyond architectural meme monolith and architectural memeplex, and has formed a highly coupled and complex cultural system. The clustering coefficients of the architectural meme networks in the cultural pattern of urban architecture in different periods are all between 0.575 and 0.676 (more than 0.5), suggesting that the cultural similarities within the clusters of architectural heritages in the city have the characteristics of continuous heredity. The methodology and conclusions of this study can provide a methodological reference for the design of contemporary urban architecture cultural patterns, and provide data support for the development and improvement of urban historic district conservation planning.
Livestock ownership and reproductive characteristics, but not maize production, are associated with anemia in women in malaria-endemic low-income setting
Authors: Zerfu Taddese Alemu , Ketema Wegderes , Abera Amare , Belay Abera 
Published: March 2024

Abstract

Background:It is unclear whether common agricultural practices, such as livestock farming and maize production, affect the burden of malaria and subsequent anemia status among reproductive-age women in a low-income setting.Methods: A community-based cross-sectional study was conducted among women of reproductive age, comparing areas with high versus low maize production intensity in rural central Ethiopia. The study areas were categorized as high (> 50%) or low (≤ 10%) maize production clusters based on the percentage of cultivated land. Data were collected from 450 randomly selected households (250 from each cluster). Descriptive and bivariate statistics were used to outline the participants' profiles and the association of variables. Multivariate linear regression was applied to identify determinants of mean hemoglobin concentration levels.Results: The mean (± SD) hemoglobin concentration remained statistically consistent across high 13.59 (± 1.39 g/dl) and low 13.39 (± 1.65 g/dl) maize-intensity clusters (P > 0.05). Women's ownership of livestock (β, 0.13; 95% CI: 0.01, 1.12), chicken production (β, 0.21; 95% CI: 0.34, 1.01), and women's parity (β, 0.67; 95% CI: 0.17, 0.61) significantly increased hemoglobin concentration levels (P < 0.05). Conversely, gravidity (β, -0.82; 95% CI: -0.65, -0.21) and the frequency of abortions (β, -0.23; 95% CI: 0.31, 1.06) significantly decreased hemoglobin concentration levels (P < 0.05).Conclusion: Regardless of maize production intensity, women's reproductive characteristics and livestock farming (especially chicken production) were identified as independent predictors of hemoglobin levels. Therefore, promoting women's reproductive health care and livestock-based agricultural practices could enhance the health status of agrarian women in low-income settings.