bluuebunny/crossref_metadata_2025_split huggingface dataset:
Dopaminergic Drugs and Valproate-associated Refractory Hyponatremia Over Levosulpiride-induced Parkinsonism in an Elderly Female Patient
When Deprescribing was the Only Therapy
Authors: Dehade Amol , Chakrabarti Sankha Shubhra , Reddy Not Taruni Srija , Kaur Upinder 
Published: March 2024

Introduction:
Prescribing cascade is a condition in which a drug administered to a
patient causes an adverse reaction that is misinterpreted as a new condition, resulting in the addition
of a new drug.

Case Presentation:
Here, we report the case of an elderly female patient who suffered from
metabolic, neurologic, and urinary consequences of a prescribing cascade of antiemetic, antiepileptic,
and dopaminergic drugs. While levosulpiride caused Parkinsonian symptoms, the dopaminergic
drugs and valproate caused refractory hyponatremia followed by altered sensorium,
and clidinium contributed to urinary retention.

Conclusion:
The case highlights the need to be vigilant for adverse consequences of the prescribing
cascade, especially for antiemetic drugs, such as levosulpiride, because of its propensity
to induce extrapyramidal reactions in older patients. In cases of refractory hyponatremia, a trial
of de-challenge of valproate and dopaminergic drugs should be considered. In addition, the identification
and removal of the culprit drugs can rescue the patient from a disabling cycle of adverse
drug reactions.
An Alternative Concept in Making Hybrid Flow Batteries into Dendrite-Free Full-Flow Batteries
Authors: Weng Guo-Ming 
Published: March 2024

:
In this study, the author proposes an alternative concept of using electrostatic force of
cation-exchange resin to attract metal ions and nanoscale conductors onto the polymer matrix to
conduct the electrons for the plating/stripping of the metal species. Due to the even distribution of
the positively-charged functional groups inside the cation-exchange resin, metal formation can
also be well distributed and safety issue caused by metal dendrite can be eliminated. By applying
this transformative concept, various hybrid flow batteries could be “upgraded” to dendrite-free
full-flow batteries. Interestingly, this new concept could also be generalized for all metal-based
aqueous and nonaqueous hybrid systems to upgrade them into next-generation full-flow battery
systems. This work offers an alternative concept to deliver unprecedented battery systems and the
proof-of-concept would be more easily implemented than anticipated.
Phytopharmacological Update on Cannabis sativa (Ganja): A Mini Review
Authors: Varshney Tushar , Sanduja Mohit , Pathak Devender , Sharma Anuj Kumar , Kumari Vibha , Singh Manjul Pratap , Kulshreshtha Mayank 
Published: March 2024

:
Cannabis sativa L., a significant herbaceous species in Central Asia, has long been valued for its use in traditional medicine and as a source of textile fiber. This fast-growing plant has recently drawn increased attention because of its many applications. It is an abundant source of wood and cellulosic fibers and a true treasure of phytochemicals. This plant greatly interests the construction and pharmaceutical sectors because its metabolites have potent biological ef-fects on human health. Its inner and outer stem tissues may be used to make concrete-like mate-rials and bioplastics. This study aims to summarize the molecular and scientific knowledge of Cannabis sativa, including its pharmacognostic properties, pharmacological potential, phyto-chemical properties, and prospective future research fields.
Evaluating the Potential and Pitfalls of AI-Powered Conversational Agents as Humanlike Virtual Health Carers in the Remote Management of Noncommunicable Diseases: Scoping Review
Authors: Anisha Sadia Azmin , Sen Arkendu , Bain Chris 
Published: March 2024

Background
The rising prevalence of noncommunicable diseases (NCDs) worldwide and the high recent mortality rates (74.4%) associated with them, especially in low- and middle-income countries, is causing a substantial global burden of disease, necessitating innovative and sustainable long-term care solutions.

Objective
This scoping review aims to investigate the impact of artificial intelligence (AI)–based conversational agents (CAs)—including chatbots, voicebots, and anthropomorphic digital avatars—as human-like health caregivers in the remote management of NCDs as well as identify critical areas for future research and provide insights into how these technologies might be used effectively in health care to personalize NCD management strategies.

Methods
A broad literature search was conducted in July 2023 in 6 electronic databases—Ovid MEDLINE, Embase, PsycINFO, PubMed, CINAHL, and Web of Science—using the search terms “conversational agents,” “artificial intelligence,” and “noncommunicable diseases,” including their associated synonyms. We also manually searched gray literature using sources such as ProQuest Central, ResearchGate, ACM Digital Library, and Google Scholar. We included empirical studies published in English from January 2010 to July 2023 focusing solely on health care–oriented applications of CAs used for remote management of NCDs. The narrative synthesis approach was used to collate and summarize the relevant information extracted from the included studies.

Results
The literature search yielded a total of 43 studies that matched the inclusion criteria. Our review unveiled four significant findings: (1) higher user acceptance and compliance with anthropomorphic and avatar-based CAs for remote care; (2) an existing gap in the development of personalized, empathetic, and contextually aware CAs for effective emotional and social interaction with users, along with limited consideration of ethical concerns such as data privacy and patient safety; (3) inadequate evidence of the efficacy of CAs in NCD self-management despite a moderate to high level of optimism among health care professionals regarding CAs’ potential in remote health care; and (4) CAs primarily being used for supporting nonpharmacological interventions such as behavioral or lifestyle modifications and patient education for the self-management of NCDs.

Conclusions
This review makes a unique contribution to the field by not only providing a quantifiable impact analysis but also identifying the areas requiring imminent scholarly attention for the ethical, empathetic, and efficacious implementation of AI in NCD care. This serves as an academic cornerstone for future research in AI-assisted health care for NCD management.

Trial Registration
Open Science Framework; https://doi.org/10.17605/OSF.IO/GU5PX
PENGARUH GCG, ARUS KAS, LABA TERHADAP FINANCIAL DISTRESS PADA SEKTOR PARIWISATA, HOTEL DAN RESTORAN 2017-2021
Authors: Aryanti Kadek Tarisna , Sutapa I Nyoman , Dewi I Gusti Ayu Ratih Permata 
Published: March 2024

Penurunan kunjungan wisman berdampak pada pendapatan, sehingga memungkinkan adanya kondisi financial distress pada perusahaan sektor Pariwisata. Tujuan penelitian untuk menguji dan menganalisis pengaruh kepemilikan institusional, kepemilikan manajerial, dewan direksi, arus kas dan laba terhadap financial distress pada Perusahaan Sub Sektor Pariwisata, Hotel dan Restoran. Metode yang digunakan dalam penelitian ini adalah metode penelitian kuantitatif. Populasi yang digunakan dalam penelitian ini adalah Perusahaan Sub Sektor Pariwisata, Hotel dan Restoran yang terdaftar di BEI periode 2017-2021 berjumlah 35 perusahaan, sampel 18 perusahaan. Jenis data adalah data sekunder. Sumber dari halaman resmi Indonesia Stock Exchange (IDX). Metode pengumpulan data yang digunakan dalam penelitian ini yaitu metode dokumentasi. Metode analisis data yang digunakan dalam penelitian ini adalah Uji Regresi Logistik. Hasil dari penelitian ini menunjukkan bahwa secara parsial kepemilikan institusional tidak berpengaruh secara signifikan terhadap financial distress, kepemilikan manajerial serta dewan direksi berpengaruh signifikan ke arah positif terhadap financial distress, dan arus kas serta laba tidak berpengaruh signifikan terhadap financial distress. Saran yang diberikan peneliti adalah menambahkan variabel profitabilitas, likuiditas, leverage dan sales growth dan faktor non keuangan seperti kurs dan inflasi.
Pengembangan Digitalisasi Sekolah Berbasis Website pada Era Komputasi Global di SMP Muhammadiyah
Authors: Fitria Cemy Nur , Hermawan Hardika Dwi , Sayekti Ika Candra , Selfia Karunia Dwi , Azra Adilah , Prasojo Ipin 
Published: March 2024

Pengabdian ini memiliki tujuan untuk inisiasi dan pendampingan untuk digitalisasi sekolah berbasis website sebagai upaya rekognisi SMP Muhammadiyah 04 Sambi. Adapun batasan dalam Website Sekolah Menengah Pertama (SMP) Muhammadiyah 04 Sambi yaitu sekadar akan menampilkan informasi-informasi yang berisi mengenai profil, galeri, fasilitas, ekstrakulikuler, dan hal – hal yang berkaitan dengan Sekolah Menengah Pertama (SMP) Muhammadiyah 04 Sambi secara up to date dan real time. Sedangkan untuk pegumpulan data yang dilakukan dalam pengabdian ini menggunakan beberapa teknik pengumpulan data yang terdiri dari observasi dan wawancara pada pihak mitra. Software yang digunakan adalah Niagahoster sebagai media web hosting, dan Wordpress sebagai pengolahan basis datanya. Hasil pembuatan website ini dapat digunakan sebagai salah satu alternatif untuk memberikan informasi yang berkaitan dengan sekolah kepada masyarakat dengan tujuan agar Sekolah Menengah Pertama (SMP) Muhammadiyah 04 Sambi dapat lebih jauh dikenal oleh masyarakat luas. Digitalisasi sekolah berbasis website dalam mengembangkan kompetensi serta tingkat kualitas sekolah adalah suatu hal yang sangat tepat dilaksanakan karena website ialah suatu media teknologi informasi yang tergolong sangat interaktif serta dinamis dengan tujuan menambah wawasan dan juga eksistensi diri. Penerapan teknologi informasi sekolah berbasis website ini dapat diakses dimana saja dan kapan saja melalui jaringan internet.
Ecological Movement During Covid-19 Pandemic: Study of Living Quran at the Asy-Syarifiy Islamic Eco-Boarding School Lumajang-East Java-Indonesia
Authors: Syarifah Ma'isyatusy , Amin Ahmad Syaifuddin 
Published: March 2024

The ecological movement of students at the Asy-Syarifiy Pandanwangi Islamic Boarding School, Tempeh, Lumajang, East Java, Indonesia during the Covid-19 pandemic that runs the daily lives of students is very interesting to study because the Qur'an is not only read and studied as a compulsory subject for boarding schools. pesantren, but also make the Qur'an the basis for caring for the environment. The purpose of this research is to how the ecological movement in Asy-Syarfiy is, how is the actualization of the living Quran in the ecological movement in Asy-Syarfiy during the Covid-19 pandemic. The objective research of this article is descriptive qualitative research with the type of field research with the socio-religious approach of Karl Mannheim which is a sociological theory of meaning. Data collection was carried out by involving observation, documentation, and in-depth interviews in June 2021 with seven informants. This study found, firstly, that Asy-Syarifiy students have high discipline in maintaining environmental stability so that their relationship with other environmental components is balanced, especially during the pandemic. Second, students carry out the ecological movement of the Islamic boarding school by reading the verse of the chair (verse 225 of Surah Al Baqarah) every morning and evening before carrying out environmental cleaning activities for the Islamic boarding school. Third, since the pandemic, the chair verse reading activity has also been carried out after every fardhu prayer in the congregation and is read seven times because the chair verse is believed to be a form of rejecting the dangers of Covid-19. Thus, the verses of the Qur'an come alive among the students.Keywords: Ecology movement; Pandemic; Living Quran
Representasi Profesional Public Relations pada Tokoh Bae Ta Mi dalam Drama Korea Search: WWW
Authors: Putri Riza Helmi , Rosyidah Siti Nur , Damayanti Ulfa Dwi , Sari Mila 
Published: March 2024

Penelitian ini berfokus pada Representasi Profesional Public Relations Pada Tokoh Bae Ta Mi Dalam Drama Korea Search: WWW. Dengan tujuan penelitian untuk mengetahui representasi profesional Public Relations pada tokoh Bae Ta Mi dalam drama Korea Search:WWW dengan memanfaatkan sudut pandang kajian semiotika John Fiske. Hasil penelitian ini tokoh Bae Ta Mi memenuhi syarat profesional Public Relations dari ketiga level kajian semiotika John Fiske. Baik dari level realitas, representasi dan ideology. Tokoh Bae Ta Mi dapat merepresentasikan seorang profesional Public Relations. Dalam drama yang menggambarkan tentang kemajuan teknologi komunikasi di mana membahas tentang persaingan dua perusahaan portal web, Bae Ta Mi sebagai Public Relations yang bekerja di sana digambarkan berintegritas dan berkualitas
FUNDING AND OVERFUNDING PHENOMENA IN CROWDFUNDING: RELEVANCE OF PLATFORM CHOICE AND VARYING INDUSTRY DYNAMICS
Authors: Galkiewicz Dominika , Galkiewicz Michal 
Published: March 2024

This study provides new evidence on factors relevant for the success of crowdfunding campaigns run in Europe between 2015 and 2017 on the most popular crowdfunding platforms in Germany/Austria – Kickstarter.com and Startnext.com. In particular, for this study, a sample of 10,514 campaigns from Germany and Austria for the first time serves as a basis for identifying the determinants of the level of projects’ (over-)funding. For crowdfunding projects, an increase in a project’s funding goal results in higher funding on both platforms, but this does not guarantee success, i.e. reaching the relevant funding goal. Projects with a higher success probability show lower funding goals, especially if launched on Startnext.com. In contrast, a longer duration negligibly increases the amount raised on Startnext and slightly decreases on Kickstarter. On Startnext, projects from the Art cluster have a higher chance to succeed, while these from the Technology cluster show smaller success probabilities as they regularly get less funding. On Kickstarter, projects from the Art, Technology, or Lifestyle field reach higher financing as compared to the Sustainability area. We show that the uncertainty about market size and project/founder quality leads to diverging over- and underfunding levels across platforms and industry clusters, which is of core importance to interested stakeholder groups.
Key words: crowdfunding, crowd, reward, Kickstarter, Startnext
Urgensi Pembentukan Undang-Undang Pengelolaan Perubahan Iklim di Indonesia
Authors: Arfah Mohammad Misbaqul , Rahmawati Ichah Yunia , Ferdiyantoro Denny , Afilah Aminatul , Amalia Harum Rizky 
Published: March 2024

Perubahan iklim adalah permasalahan global dengan dampak negatif yang besar. Dampak negatif dari perubahan iklim sangat luas, mulai dari dampak sosial, ekonomi, hingga sumber daya alam. Penelitian ini mengkaji urgensi pembentukan Undang-Undang (UU) Pengelolaan Perubahan Iklim di Indonesia dari aspek filosofis, sosiologis, dan yuridis serta studi komparatif hukum perubahan iklim Indonesia dengan negara lain, yaitu Meksiko dan Korea Selatan. Penelitian ini diklasifikasikan sebagai penelitian hukum normatif dengan pendekatan peraturan perundang-undangan (statute approach) dan pendekatan komparatif (comparative approach). Hasil dari penelitian ini menunjukan bahwa Indonesia belum memiliki kerangka kebijakan yang jelas dan terukur. Sejatinya, pengaturan terkait dengan perubahan iklim telah diatur dalam beberapa peraturan. Namun demikian, peraturan-peraturan tersebut masih bersifat sektoral. Lebih lanjut, peraturan-peraturan terkait dengan perubahan iklim yang telah ada di Indonesia masih belum merujuk pada sebuah peraturan induk adaptasi perubahan iklim yang memiliki daya jangka lebih luas dan panjang. Selain itu, peraturan-peraturan tersebut juga belum terintegrasi dengan setiap kebijakan pembangunan nasional. Oleh karena itu, UU Pengelolaan Perubahan Iklim diyakini menjadi sebuah peraturan induk serta kerangka kebijakan yang jelas dan terukur berkaitan dengan pengelolaan perubahan iklim. Selain itu, studi komparatif yang dilakukan menunjukkan bahwa peraturan khusus perubahan iklim di Meksiko dan Korea Selatan terbilang efektif untuk memerangi perubahan iklim.
Keywords: UU Pengelolaan Perubahan Iklim; Studi Komparatif; Meksiko; Korea Selatan
Kebijakan Hukum Pidana dalam Pertanggung Jawaban Korporasi yang Melakukan Tindak Pidana Korupsi
Authors: Sofiatul Istiqomah  , Abdul Rokhim  , Diyan Isnaeni  
Published: March 2024

Penelitian ini bertujuan untuk menganalisis kebijakan hukum pidana dalam pertanggungjawaban pidana oleh korporasi di Indonesia, dan untuk menganalisis penerapan sanksi pidana terhadap korporasi yang melakukan tindak pidana korupsi dalam hukum positif di Indonesia. Penelitian ini merupakan jenis penelitian yuridis normatif, dengan menggunakan pendekatan perundang-undangan dan pendekatan konseptual. Sedangkan untuk metode analisis data yang digunakan adalah metode deskriptif, metode evaluatif, dan metode Argumentatif. Hasil dari penelitian ini menerangkan bahwa kebijakan hukum pidana dalam pertanggungjawaban pidana oleh korporasi di Indonesia lahir dari adanya perbuatan melawan hukum a criminal act (actus reus) dan terpunihinya unsur kesalahan a criminal intent (mens rea) sehingga dari segi objektif terhadap perbuatan yang dinyatakan sebagai tindak pidana yang berlaku dan secara subjektif kepada korporasi sebagai pelaku tindak pidana yang memenuhi persyaratan untuk dapat dikenai pidana karena perbuatannya. Serta penerapan sanksi pidana terhadap korporasi yang melakukan tindak pidana korupsi dalam hukum positif di Indonesia diatur dalam ketentuan Pasal 2 dan Pasal 20 UU No. 31 Tahun 1999 tentang Pemberantasan Tindak Pidana Korupsi, yang memberikan pemahaman bahwa pertanggungjawaban pengganti dapat diterapkan jika masih dalam kewenangan pimpinan korporasi serta mengatur penerapan pidana pokok hanya dapat diganti dengan pidana denda serta pidana tambahan 1/3.
Keywords: Korporasi; Korupsi; Pertanggungjawaban Pidana
PENGARUH PENGGUNAAN METODE DISKUSI BERBANTUAN MEDIA VIDEO ANIMASI UNTUK MENINGKATKAN HASIL BELAJAR PESERTA DIDIK
Authors: Ardika Bela , Kartini Kartini , Septianawati Desti 
Published: March 2024

This research was motivated by the low learning outcomes of grade II students at SDN 02 Galing District. This study aims to describe: 1) Student learning outcomes in grade 2 mathematics subject. 2) The steps on how to utilize the discussion method assisted by animated video media. 3) The influence of the use of discussion methods assisted by animated video media. 4) how influential the use of the animated video-assisted discussion method.
The type of this research is quantitative research with a pre-experimental design with a One Group Pretest-Posttest design. The location of this study was located at SDN 02 Galing District as the source of data for research was II grades consisting of 22 students. The techniques of data collection in form of tests, observation and documentation. The tools of data collection include multiple-choice written tests (pretest-posttest), observation sheets and documentation (mobile phone and camera). The data analysis used is descriptive analysis and inferential analysis using a normality test and hypothesis test (t-test).
The conclusions of this study are: 1) Pretest and posttest learning outcomes, with the average score of pretest learning outcomes of 50.91 and the average score of posttest learning outcomes of 72.27. 2) The results of the observation sheet that have been observed by the teacher of 2 grades that the steps on how to utilize the discussion method assisted by animated video media have all been implemented. 3) The results of the pretest normality test of 0.021 > 0.005 the resulting data are normally distributed and in the posttest normality test of 0.200 > 0.005 the data result is normally distributed. In the t-test analysis of two samples paired with assisted IBM SPSS 23 statistics obtained that probability (sig. (2- tailed)) 0.00 < 0.005 then Ho was rejected and Ha was accepted in other words there were differences in learning outcomes before and after using animated video media. 4) Amount of the influence on the use of discussion methods assisted by animated video media to improve student learning outcomes in mathematics subject in grade II SDN 2 Galing District is 61.4%.
Physical signs and atherosclerotic cardiovascular disease in familial hypercholesterolemia: the HELLAS-FH Registry
Authors: Rallidis Loukianos S. , Rizos Christos V. , Papathanasiou Konstantinos A. , Liamis George , Skoumas Ioannis , Garoufi Anastasia , Kolovou Genovefa , Tziomalos Konstantinos , Skalidis Emmanouil , Kotsis Vasileios , Sfikas George , Doumas Michalis , Anagnostis Panagiotis , Lambadiari Vaia , Giannakopoulou Vasiliki , Kiouri Estela , Anastasiou Georgia , Petkou Ermioni , Koutagiar Iosif , Attilakos Achilleas , Kolovou Vana , Zacharis Evangelos , Antza Christina , Koumaras Charalambos , Boutari Chrysoula , Liberopoulos Evangelos 
Published: March 2024

Aims
Three physical signs, namely tendon xanthomas, corneal arcus and xanthelasma, have been associated with heterozygous familial hypercholesterolemia (heFH). The prevalence and clinical significance of these signs are not well established among contemporary heFH individuals. This study explored the frequency as well as the association of these physical signs with prevalent atherosclerotic cardiovascular disease (ASCVD) in heFH individuals.

Methods
Data from the Hellenic Familial Hypercholesterolemia Registry were applied for this analysis. The diagnosis of heFH was based on the Dutch Lipid Clinic Network Score. Multivariate logistic regression analysis was conducted to examine the association of heFH-related physical signs with prevalent ASCVD.

Results
Adult patients (n = 2156, mean age 50 ± 15 years, 47.7% women) were included in this analysis. Among them, 14.5% had at least one heFH-related physical sign present. The prevalence of corneal arcus before the age of 45 years was 6.6%, tendon xanthomas 5.3%, and xanthelasmas 5.8%. Among physical signs, only the presence of corneal arcus before the age of 45 years was independently associated with the presence of premature coronary artery disease (CAD). No association of any physical sign with total CAD, stroke or peripheral artery disease was found. Patients with physical signs were more likely to receive higher intensity statin therapy and dual lipid-lowering therapy, but only a minority reached optimal lipid targets.

Conclusion
The prevalence of physical signs is relatively low in contemporary heFH patients. The presence of corneal arcus before the age of 45 years is independently associated with premature CAD.