bluuebunny/crossref_metadata_2025_split huggingface dataset:
Analysis of Fault Detection in Analog Circuits Using WSF-SKC Optimized SVM Technique
Authors: R. Gurunadha Et al. 
Published: February 2024

Many industrial applications and control systems depend heavily on analogue electrical circuitry. The conventional method of diagnosing such circuit faults can be time-consuming and erroneous, which might have a severe impact on the industrial output. The fault detection and analysing of analogue circuits with intelligent effective model is proposed in this work. The suggested technique primarily consists of two main stages one is extraction of features and the other is classification of faults. The analysis is performed on the response of frequency in analogue circuits. For extracting features particle swarm optimization (PSO) is utilized. The PSO is used to evaluate the fitness function of Wilks A-Statistic Filters sallen-key circuit (WSF-SKC). With fault characteristics retrieved using the particle swarm approach that are carefully selected, the fault classes may be separated more quickly. To categorise different failures in a benchmark circuit, a Support Vector Machine (SVM) classifier is built. Utilising firefly optimisation, the classifier is improved. Different fault codes were tested in experiments for defect detection and identification. The findings of the experiment indicate that this proposed technique can significantly increase the accuracy of fault diagnosis. The accuracy obtained for WS-LPF is 99.95%, WS-HPF is 99.97 and WS-BPF is 99.90% respectively.
Engaging Epistemic Tensions in Graduate Education
Authors: Diaz Lucas , McBride Ryan , Soto-Olson Diana , Nance Agnieszka 
Published: February 2024

Productive tensions with traditional academic practices develop from a graduate certificate program in community engagement at Tulane University. The program offers an alternative approach to graduate education by fostering community, epistemic justice, and care for the whole person through sustained interdisciplinary and transdisciplinary conversations and collaborations. A 2021-22 survey of current and prior program participants in the graduate certificate program documents a variety of tensions that arise when the graduate certificate program is compared to students’ other experiences with graduate school at Tulane.

Analysis relies on theories and concepts of epistemic injustice, decolonizing methodologies and community engagement, which enables interpretation of results. We find that results point to the Tulane Mellon Graduate Program in Community-Engaged Scholarship’s differences in approaches as compared to traditional graduate educational experiences at Tulane, offering insights into more ethical and humane possibilities for graduate education generally as well as particular insights into community-engaged graduate education. These insights would be useful to graduate program directors, graduate students, community-engagement advocates, and administrators interested in connecting their universities to local communities through ethically informed scholarly collaborations.
Gender difference in foot progression angle in patients with osteoarthritis knee: an observational cross-sectional study
Authors: Rastogi Aavrati , Kalia Roop B. 
Published: February 2024

Background: An essential clinical parameter related to gait is foot progression angle (FPA). The objective of this study was to evaluate foot progression angle difference between Kl grade 2 and 3 in osteoarthritis knee patients and understanding biomechanical factors associated knee OA.
Methods: Study was conducted on 108 patients diagnose with osteoarthritis knee according to EULAR classification knee OA. Age, gender and BMI were recorded, gait analysis was done to evaluate difference in FPA between OA knee patients with KL grade 2 and 3.
Results: The 108 patient, 68 female and 40 males with osteoarthritis knee were included in study. Mean age of patients was 55.92±0.8 year, mean BMI was 27.24±0.4 kg/m2. Mean and SD of FPA in male 7.31±3.60 and in female 8.31± 4.18 in patients with Kl grade 2 and 3 mean difference between male and female FPA is -0.99 with 95% CI, p=0.43 and t=0.78. In KL grade 3, FPA mean and SD of male 6.79±2.80 and female 7.62±9.10, t=0.9, mean difference -0.83 with 95% CI and p=0.6925.
Conclusions: This study suggests, females in comparison to males have less FPA and therefore, females are more prone in progression of knee OA. Potential confounders including age, gender, BMI disease severity did not alter magnitude, although 95% CI.
Complications of thyroidectomy: Insights from a single-centre study in northeast India
Authors: Baral Sonia , Borgohain Rupam , Timungpi Geeta 
Published: February 2024

To study and compare the frequency of post-operative complications associated with thyroid surgeries indicated for various benign and malignant pathologies and assess the outcome of management of such complications in a tertiary care hospital in Northeast India. An analytical study was done at a tertiary care hospital in Assam over a period of 1 year from May 2022 to June 2023. Data was collected from 53 patients who underwent surgery at this hospital. Hemithyroidectomy, subtotal, near-total, and total thyroidectomies were performed in 31(58.4%), 2 (3.7%), 6 (11.3%) and 14 (26.4%) cases respectively. The overall rate of complications was 39.6%. Permanent hypocalcaemia was observed to be the most common complication, followed by transient hypocalcaemia and transient recurrent laryngeal nerve palsy. The complications were found to be more frequent in surgery for malignant thyroid disease. There was no mortality in our study. A better understanding of thyroid gland anatomy, meticulous haemostasis and Identification of Recurrent laryngeal nerve and parathyroid glands lead to favourable post-operative outcomes. Appropriate post-operative care with early identification and management of complications plays an essential role in reducing the duration of postoperative hospital stay and limiting patient morbidity.
Przymiot drugiej strony jako przedmiot podstępnego wprowadzenia w błąd (kan. 1098 KPK) w orzecznictwie Roty Rzymskiej (2000-2005)
Authors: Góralski Wojciech 
Published: February 2024

Tytuł nieważności małżeństwa w postaci podstępnego wprowadzenia w błąd (can. 1098) stanowi wyraz troski ustawodawcy kościelnego o ochronę wyboru małżeńskiego (poznanie przyszłego małżonka), a także o ochronę samego małżeństwa przed niesprawiedliwością. Jednym z elementów konstytutywnych kanonu – poza podstępem i błędem – jest przymiot drugiej strony (qualitas personae), który może poważnie zakłócić wspólnotę życia małżeńskiego.
Autor analizuje 17 wyroków Roty Rzymskiej z lat 2000-2005 wydanych z tytułu deceptio dolosa w aspekcie przymiotu drugiej strony. W części pierwszej zwraca uwagę na zasady interpretacyjne orzecznictwa rotalnego dotyczące przymiotu osoby in genere, a więc samego pojęcia qualitas, charakteru przymiotu i oceny jego znaczenia dla wspólnoty życia małżeńskiego. Natomiast w części drugiej omawia przymiot osoby in specie, a więc wskazuje na konkretne przymioty, które były przedmiotem oceny sędziów Roty Rzymskiej w owych siedemnastu sprawach (stan zdrowia, ojcostwo dziecka, uzależnienie od zabobonów, religijność, dokonanie aborcji, symulowana ciąża).
Zapoznane dzieło Jana Styki w kościele ojców jezuitów w Łodzi
Authors: Stefański Krzysztof 
Published: February 2024

Obecny kościół ojców jezuitów w Łodzi pw. Najświętszego Serca Jezusa to dawny (do 1945 r.) kościół ewangelicko-augsburski pw. św. Jana Ewangelisty, wzniesiony w latach 1880–1884. W jego ołtarzu głównym zawisło dzieło Jana Styki zatytułowane Chrystus nauczający uczniów i rzesze ludu, ufundowane przez jednego z najbardziej znanych łódzkich przemysłowców Juliusza Kunitzera. Obraz powstał w ciągu 1885 r., a w kościele został zawieszony w styczniu następnego roku. Wzbudził duże zainteresowanie w Łodzi i w Warszawie. Jego surowa forma artystyczna dostosowana została do wymogów kultu luterańskiego.
To zadecydowało zapewne, że w momencie przejęcia kościoła w 1945 r. przez jezuitów obraz został zdjęty z ołtarza głównego i przeniesiony na emporę. Tam znajdował się przez kilkadziesiąt lat. Zainteresowano się nim dopiero pod koniec ubiegłego stulecia, kiedy rozpoczęto renowację świątyni. Obraz został poddany konserwacji i pojawiły się plany jego zawieszenia na ścianie prezbiterium. Do dziś nie zostały jednak zrealizowane. Obraz znajdował się przez kilka lat w domu zakonnym ojców jezuitów, a obecnie zawisł na tylnej ścianie towarzyszącej kościołowi kaplicy św. Krzysztofa. To wysokiej klasy dzieło sztuki religijnej, jedno z najlepszych w dorobku Styki, którego losy są znamienne dla przemian zachodzących w Polsce po 1945 r., wciąż czeka na docenienie i właściwe wyeksponowanie.
Quality Evaluation of Refrigerated Salted Butter Made with Goat and Cow Milk
Authors: Pradana Mahendra Wahyu Eka , Murti Tridjoko Wisnu 
Published: February 2024

Butter is a dairy product that is susceptible to oxidation, which causes a rancid taste and a short shelf life. The quality of the butter depends on the quality of milk. The aim of the study is to determine the quality of butter made from goat and cow reared by small-scale farmers in Yogyakarta with the traditional manufacturing process. The milk of Saanen-Peranakan Ettawa (Sapera) goats and Fresian Holstein were taken from farmers in Sleman district, Yogyakarta, Indonesia. Butters were sampled after 0, 15, 30 days storage. This study used the Nested Design method , namely the nested quality of butter in the type of milk. The result showed that butter made from cow milk produced a higher fat content compared to goat milk butter (P<0.05), namely 85.29 ± 0.04% and 80.10 ± 0.27%. The acid value increased while pH value was decreased during storage (P<0.05). There was no increase in peroxide value in cow butter but there was an increase in goat butter on day 0 to day 15 (P<0.05). It can be concluded that the goat and cow milk reared by small-scale farmers in Yogyakarta have good quality so it produced good quality butter which is still good for consumption until 30 days of storage in the refrigerator.
Ecological dynamics of anoxygenic microorganisms in stably redox-stratified waters: Intra and inter-seasonal variability of Lake Cadagno
Authors: Storelli Nicola , Steiner Oscar Sepuveda , Nezio Francesco Di , Roman Samuele , Buetti-Dinh Antoine , Bouffard Damien 
Published: February 2024

Abstract
Lake Cadagno (Switzerland) differs from common alpine lakes, as it consists of two stratified layers of water that never vertically mix. This particular environment is a niche for the development of ancient anoxygenic microorganisms similar to those that populated the primordial oceans – which accumulate in the lower part of the chemocline. Yet, linkages between the temporal variation of abiotic factors, controlling stratification, with anoxygenic phototrophic sulfur bacteria community of the bacterial layer (BL) remain unclear. We studied the intra- and inter-seasonal stability of the water column stratification and population dynamics of the BL for three years to address this gap. Analyses of this extended continuous monitoring show the redox-stratified environments of the lake is remarkably stable, with stratification seemingly unaffected by abiotic factors. In contrast, the BL community showed significant intra- and inter-seasonal variability. The distinct weather conditions observed during these three years strongly influenced the composition and development of the BL community. Indeed, especially at the intra-seasonal level, the main populations monitored showed different dynamics each year. The lake's recent history also revealed the same trend. In fact, over the last 35 years, the stability of the meromixis remained unchanged, while the BL community showed considerable variability.
Brain connectome from neuronal morphology
Authors: Wang Jinhui , Jin Suhui , Li Junle 
Published: February 2024

Abstract

Morphological brain networks derived from macroscopic structural magnetic resonance imaging have become prevalent, yet lack microscopic validation. Here, we proposed a method to construct morphological brain networks at the single-cell level by estimating inter-neuron similarity for rat, mouse, and human. We demonstrated the feasibility and generalizability of the method by showing that inter-neuron morphological similarity was correlated with neuronal axonal projections, was higher for intra- than inter-class connections, depended on cytoarchitectonic, chemoarchitectonic, and laminar structures of neurons, and differed between regions with different evolutionary timelines. Furthermore, highly connected hub neurons were disproportionately located in superficial layers, inhibitory neurons, and subcortical regions, and exhibited unique morphology. Finally, we demonstrated a more segregated, less integrated, and economic network architecture with worse resistance to targeted attacks for the human than mouse. Overall, our findings provide microscopic support for using structural magnetic resonance imaging-based morphological brain networks to study the wiring patterns in brains.
Semantic Inhibition is impaired in college students with depressive traits. EEG and pupillometric evidence with the Hayling’s task
Authors: Jan Damián , López-Pigüi Joana , Padrón Iván , de Vega Manuel 
Published: February 2024

Abstract

In this study we tested whether depression is associated with impaired semantic inhibition, resulting in symptoms of rumination and anhedonia. To this aim, college students with depressive traits (DEP) and matched controls (CTL) performed a Hayling’s task, while EEG and pupillometry measures were recorded. Participants were asked to complete sentential contexts with either a highly associated word (initiation) or a non-related word (inhibition), in response to randomly presented trial-by-trial cues. The DEP group, compared to the CTL group, showed lower performance, and reduced frontal negativity (N450) in inhibition trials. Source analyses revealed greater activation for inhibition trials than for initiation trials in the bilateral orbitofrontal cortex for the CTL group, but the difference was reduced and right lateralized for the DEP group. In addition, the DEP group showed more pupil size reactivity to inhibition trials than the CTL group, indicating higher cognitive effort during semantic inhibition. Finally, self-reported rumination and anhedonia correlated with N450 in inhibition trials. Overall, this research contributes to understanding the neural underpinnings of impaired semantic inhibition in subclinical depressive participants, with potential clinical applications.
The correlation between Framingham risk score and hypertension combined with hyperuricemia in an elderly community-based population--a 7-year cohort follow-up study
Authors: Shen Chaonan , Li Xin , Li Weipeng , Liu Jie , Zhang Yuzhen , Liu Zhongmin , Zheng Liang 
Published: February 2024

Abstract
Background
Research has consistently demonstrated a robust association between hypertension (HTN) and hyperuricemia (HUA), indicating a potential synergistic effect on cardiovascular disease (CVD) risk. This study aims to explore the epidemiological characteristics of hypertension combined with hyperuricemia (HTN-HUA) and to identify the risk factors contributing to its incidence.
Methods
This study was a cohort follow-up, utilizing a community-based cohort consisting of older adults aged 65 years or older. Initially, the study enrolled 3,950 participants in a prospective manner. After the exclusion of cases with missing data, the analysis ultimately included 3,089 participants. We employed the Framingham Risk Score (FRS) formula to estimate the risk of CVD. Survival analysis was conducted to explore the relationship between FRS and CVD death/all-cause mortality. Furthermore, multiple logistic regression models were utilized to assess the association between FRS and HTN-HUA.
Results
Within the study population, we found that approximately 29.6% of hypertensive patients were also suffering from HUA. We observed that regardless of the presence of HTN or HUA, age, WC, SBP, DBP, Scr, and UA levels were significantly higher in the High-risk group than in the L-M risk group (P < 0.05). The Kaplan-Meier survival analysis, which used CVD death as the endpoint, revealed a significant difference in survival curves between the High-risk and low-intermediate (L-M) risk groups among relatively healthy individuals (P < 0.01). Furthermore, following adjustments for confounding variables, logistic regression analysis revealed that the risk of HTN-HUA in the High-risk group was 1.485 times greater than in the L-M risk group (OR = 1.485, 95% CI: 1.092–2.021).
Conclusion
In a community-based elderly population in China, the prevalence of HTN-HUA was found to be 17.5%. The FRS effectively predicted a 10-year cardiovascular risk in a relatively healthy population. Additionally, waist circumference (WC) and body mass index (BMI) were identified as significant risk factors for the development of HTN-HUA.
Regeneration of the Caudal Fin of Atractosteus tropicus The Tropical Gar
Authors: Rios-Flores Alberto J. , López-Flores Sandra , Martínez-Moreno Jose A. , Falcon-Romero Karen Y. , Ascencio-Alcudia Gloria G. , Sepúlveda-Quiroz Cesar A. , Martínez-García Rafael , González Carlos A. Alvarez , Rodríguez-Salazar Elizabeth , Maldonado Ernesto 
Published: February 2024

Abstract

Bacground:
The tropical gar (Atractosteus tropicus) belongs to the lepisosteidae family, with habitats from southeast Mexico to the south of Costa Rica. Due to its phylogenetic position, slow evolution speed (base substitution), dense genetic map, gene similarity with human beings, and ease of cultivation in laboratories, this organism provides a unique link between tetrapods and the biomedical models of teleosts. This fish is a taxonomic sister group to teleosts such as the zebrafish (Danio reiro), which possesses a high regenerative ability; however, it is not known if the tropical gar shows this same regeneration ability and whether it is similar or identical.
Results
This study aims to demonstrate the regeneration process of the caudal fin through skeletal and histological staining. For this reason, several juvenile organisms were studied for about two months, fed with artemia (Artemiidae), and anesthetized by immersion with 1% eugenol to carry out the amputation of the caudal fin and obtain the daily samples at different time points or dpa (days post-amputation) dpa. The skeleton was stained with alcian blue and alizarin red to observe the regeneration of the fin by the growth of new cartilage. Histological staining with hematoxylin and eosin was also carried out. Histological sections were made from each sample and stained, observing the regeneration on the uppermost part of the amputation.
Conclusions
The findings show are remarkable ability for caudal fin regeneration in juvenile individuals from the tropical Gar. Since Garfish are the phylogenetically sister group of teleost fish it offers an opportunity for future research in tissue regeneration.
Arabidopsis endoplasmic reticulum-localized acyltransferase LPAT2 interacts with ATI1/2 and mediates lipid droplet proliferation
Authors: Zhang Qun , Li Wenyan , Liu Wenbao , Yuan Siqi , Liao Qi , Jia Qianru , Li Xuebing , Yuan Jingya , Zhang Wenhua 
Published: February 2024

Abstract
Lipid droplet (LD) biogenesis from the endoplasmic reticulum (ER) is accompanied by conversion of phospholipids to triacylglycerol and expansion of phospholipid monolayer surface. The determinants of this process are largely unknown in plants. Here, we demonstrate that the Arabidopsis thaliana lysophosphatidic acid acyltransferase, LPAT2, and its product phosphatidic acid (PA), are critical lipid-based cues for LD proliferation. RNAi suppression of LPAT2decrease PA accumulation at the monolayer surface of LDs, consequently compromising dark- or stress-induced LD biogenesis, whereas overexpression of LPAT2 exhibits opposite effects. Furthermore, LPAT2 physically interacts with ATG8-interacting protein 1/2 (ATI1/2), which serve as autophagy cargo receptors. Mutations of ATI1/2 drastically disrupted LPAT2 translocation from the ER to the forming LDs. Our data suggest that the LPAT2-ATI1/2 complex is the core protein machinery that facilitates LD biogenesis to mediate plant responses to developmental and environmental stimuli.
Locals' perceptions, knowledge, and attitudes regarding the conservation of the critically endangered Phataginus tricuspis; Reflections on OECM Sites in Osun State, Nigeria
Authors: OWOLABI Bibitayo Ayobami , AKINSOROTAN Oluseun Adesola , ADEWUMI Abraham Adebayo Adewumi , SANUADE Adedamola Oyinade 
Published: February 2024

Abstract

This study evaluates local communities' knowledge, attitude, and perception towards the critically endangered African Tree Pangolin and its conservation in the 15 identified Other Effect Area Based Conservation Measures (OECM) sites in Osun State, Nigeria. 360 participants aged 20 and older participated in the study, which found that 90.33% supported the presence of African Tree Pangolin. However, 61% affirmed that their population is reducing due to hunting and habitat loss from poor agriculture. 67% of interviewees believed that benefits from wildlife through tourism, insect regulation, bush meat, and medicine influenced their attitudes and perceptions towards conservation. 33% of the local population changed their attitude and perception towards conservation. African Tree Pangolin conservation was deemed a priority by those with higher levels of education, but the majority of respondents claimed that the idea was unsupported because of the high revenue generated by Pangolin sales. Increasing public awareness through media, handbills, billboards, seminars, and films could help mitigate poor attitudes towards African Tree Pangolin conservation.
Human Umbilical Cord Mesenchymal Stem Cell-Based Gene Therapy for Hemophilia B using scAAV-DJ/8-LP1-hFIXco Transduction
Authors: Bu Zibin , Lou Jintu , Xu Weiqun , Zhang Lingyan , Tang Yongmin 
Published: February 2024

Abstract

Background
Hemophilia B is an X-linked bleeding disorder caused by a mutation in the gene responsible for encoding coagulation factor IX (FIX). Gene therapy offers promising potential for curing this disease. However, the current method of relatively high dosage of virus injection carries inherent risks. The purpose of this study was to introduce a novel scAAV-DJ/8-LP1-hFIXco vector transduced human umbilical cord blood derived mesenchymal stem cells (HUCMSCs) as an alternative cell-based gene therapy to conventional gene therapy for Hemophilia B.
Methods
The human FIX activation system was employed for detection. The RNA and protein expression levels were evaluated using PCR and western blot techniques. In animal studies, clotting time was utilized as a parameter for bleeding assessment. The immunohistochemical analysis was used to assess the distribution of HUCMSCs. The safety of this cell-based gene therapy was evaluated using hematoxylin-eosin staining.
Results
Our findings demonstrate that transduction of HUCMSCs with the scAAV-DJ/8-LP1-hFIXco vector results in consistent and sustainable secretion of human FIX both in vitro and in vivo. The secretion level is comparable to that observed following intravenous injection with a high dose of the viral vector. After a 5-month observation period, no tumor-related tissues were observed in any of the mice studied.
Conclusions
we have successfully developed a novel cell-based gene therapy for the potential and safer treatment option for Hemophilia B.