bluuebunny/crossref_metadata_2025_split huggingface dataset:
THE ACID-BASE CHANGES IN HIGHLY QUALIFIED ORIENTER SPORTSMEN UNDER THE INFLUENCE OF GLUCOSE ELECTROLYTE DRINK WITH THE PLANT EXTRACTS ADDITION
Authors: Biryukova Yelena A. , Khusainov Denis R. , Burtseva Yelena V. , Mishin Nikolay P. , Tribrat Natalya S. 
Published: March 2024

In real conditions of high-intensity training and competitive load of athletes, the most important for sports success is the preservation of energy metabolism indicators, and, in particular, the acid-base balance in the range of homeostatic normal values. One of the possible ways to maintain the acid-base balance of an athlete is the use of homeostatic electrolyte drinks, which can have a fairly rapid effect. In this regard, for our work we have identified the following goal of the study: to analyze the possibility of using the functional drink "Aluston" (FDA) produced by JSC "Alushta Essential Oil Plant" to maintain the acid-base balance of athletes and a possible increase in performance, training duration, resistance of athletes to long-term physical activity of high intensity.
Methods: Stepwise loading protocol was used on a Kettler bicycle ergometer (Hmbq, Germany). Capillary blood sampling from athletes was carried out at rest before the start of the load and immediately after it was completed using an Epoc capillary (Epocal Inc., Canada). Biochemical parameters of blood like pH, concentration of CO2 and O2, [Na+], [К+], [Сa2+], [Cl–], [HCO3–], Lactate, Glucose, Crea, Hct, Hb, BE(ecf), BE(b ) were recorded by the Epocreader and Epochost analyzers (Epocal Inc., Canada). It was shown that FDA contributes to the stabilization of anion gaps, reduces the severity of the shift of the standard (BE-ecf) and true (BE-b) excess bases into the negative range, which can be regarded as a more pronounced preservation of the “strength” of blood buffer systems, and contributed to a decrease in tension in the pair acidosis-alkalosis. In addition, FDA supplementation likely shifts the phase of creatine fermentation to later loading stages.
The last experimental fact requires further research, and also, modification changes in the composition, concentration ratio of active components in the “Aluston” drink remain relevant.
EVALUATION OF VITICULTURE AND WINEMAKING REGIONS OF CRIMEA IN ACCORDANCE WITH CLIMATIC FACTORS, AND THEIR INFLUENCE ON THE QUALITY CHARACTERISTICS OF GRAPES
Authors: Rybalko Evgeniy A. , Cherviak Sofia N. , Ermikhina Marianna V. 
Published: March 2024

A grape plant is capable to adapt, grow and produce crops in different environmental conditions. At the same time, agro-climatic conditions of grape growing area have a significant effect on the product quality. Environmental climatic conditions of Crimea contribute to cultivating grapes from very early to late ripening varieties. Diverse range of abiotic conditions allows choosing an optimal terroir for the formation of necessary grape conditions depending on the application target. Significant spatial climate variability within the region makes it possible to evaluate the impact of environmental factors on biosynthetic and accumulative properties of grapes.
The purpose is to study changes in the profile of carbohydrate-acid complex of wine grape varieties under the influence of agro-ecological growing conditions.
Materials and methods. Study objects were white and red grape varieties growing in various viticulture and winemaking regions of Crimea. A research for grape plant response to the variability of environmental factors basing on a long-term comparative study of chemical composition of its fruits, determining the varietal biochemical identity and technological properties in a particular region, was carried out.
Results and conclusion. As a research result, the cumulative effect of agro-ecological factors on the accumulation of components of carbohydrate-acid grape complex was established, and in particular years it was possible to identify the dependence between their quantitative content and individual environmental factors. Accumulation of the mass concentration of sugars in grape berry directly correlated with the Huglin index value (r = 0.7). With regard to the mass concentration of titratable acids, an inverse correlation was revealed with the Winkler index value (r = -0.59). A comparative analysis of the results shows that one grape variety grown under different climatic conditions may show different ability to synthesize the components of carbohydrate-acid complexes, determining its suitability for various output production. There is a direct correlation of the mass concentration of sugars on the average air temperature for the last month before harvest (r=0.70) within the variety.
MORPHOLOGICAL FEATURES AND PRODUCTIVITY OF THE ATROPA L. GENUS SPECIES, CULTIVATED IN THE MOSCOW REGION
Authors: Basalaeva Irina V. , Savchenko Olga M. 
Published: March 2024

Background. The application of the anatomical method of studying various forms, varieties and species will allow to determine the degree of plant adaptation to habitat conditions and to assess its ecological plasticity.
Purpose. This work aim is to evaluate the species and breeding samples of the Atropa genus by a set of signs, including morphological description, shape, size and weight of leaves, the nature of the pubescence of the leaf plade epidermis, location, size and number of stomata, as well as the yield of raw materials.
Results. All collection samples of the studied species of the genus Atropa in the conditions of the Non-Chernozem zone of the Russian Federation undergo a full cycle of development. The assessment of the potential resistance of 14 forms and species of belladonna to unfavorable biotic and abiotic environmental factors was carried out, their main morpho-anatomical features were studied. The adaptive potential of the leaves of the studied Atropa plants is due to the variability of the structural elements of the leaf epidermis and is one of the factors of resistance to stress. In the group of studied samples, A. acuminata (406, Lithuania) and A. belladonna (487, Poland) have the lowest stress-adaptive potential (according to the set of signs). It was noted that populations of A. belladonna from Eastern Europe and France have signs of xeromorphism against the background of a decrease in plant size compared to the control and the lowest yield. It is noted that A. belladonna samples from Europe with yellow corolla staining occupy an intermediate value in yield in the presence of xeromorphic signs, which indicates their adaptability to the conditions of agrocenosis. The presence of numerous secreting trichomes in the studied accessions of A. belladonna and A. komarovii (nos. 5 and 14) may indicate their potential resistance to diseases and pests. The A. caucasica and A. komarovii species, as well as the A. belladonna specimen from Great Britain (no. 1), can be considered well adapted.
Conclusion. The highest-yielding populations are from Russia A. belladonna 15/15; A. caucasica 118 compared to the Bagira variety. These samples can be considered promising and well-adapted candidates for creating a new variety of A. belladonna.
ENVIRONMENTAL RISKS FOR PUBLIC HEALTH AS A SIGNIFICANT CRITERION FOR CREATING FUNCTIONAL ZONES IN A CITY WITHIN URBAN DEVELOPMENT
Authors: May Irina V. , Sedusova Ella V. , Balashov Stanislav Yu. , Saranina Kseniya N. 
Published: March 2024

Background. This study focuses on a vital issue concerning the necessity to consider public health when making decisions on urban development.
Purpose. Test approaches to using available data on environmental public health risks when creating functional zones in a large industrial center.
Materials and Methods. Aerogenic health risks associated with ambient air pollution were assessed by calculating dispersion of emissions from 2500 industrial sources and 4000 traffic network sections as well as by using environmental monitoring data.
Results. We established that 1889 land spots of 3619 functional zones with standardized air quality were fully or partially located in areas with unacceptable public health risks. These land spots included 905 residential areas and 984 spots with recreational potential.
Conclusion. Obviously, an inconsistency between actual health hazards for city population and a functional purpose of a zone requires immediate action. Either a functional purpose should be changed, or certain air protection activities should be implemented to make ambient air quality conform to the existing standards and to guarantee acceptable health risks levels. Either option requires environmental and economic substantiation. Any decision on changes in a specific situation in each specific functional zone should be made separately considering hazards, their sources and reasons for their occurrence. These decisions should rely on economic estimates and technical capabilities necessary for implementation of planned activities. People’s life and health should always remain the top priority. The study describes an algorithm for considering environmental factors when functional zones are created within urban development.
Application of Novosorb biodegradable temporising matrix in wounds of different aetiologies: a case series
Authors: Meagher Helen , Holmes Tara , Hanson Catherine , Chaplin Shauna , McKevitt Kevin L , Moloney Michael A , Medani Mekki , Kavanagh Eamon G 
Published: March 2024

This case study series outlines the use of Novosorb biodegradable temporising matrix (BTM, PolyNovo, Australia) in the management of 22 patients, each with a complex wound who attended the vascular department in the University Hospital Limerick between 2021 and 2023. The majority of patients presented with acute conditions (e.g. necrotising fasciitis, crush injuries, compartment syndrome) that initially required high dependency level care. The majority of wounds (21/22, 95%) affected the leg or foot, and one wound was on the chest wall. Each patient had a significant complex wound and, in many cases, was complicated further by the patients' medical condition and comorbidities, which had the potential to cause problematic and delayed healing. The BTM was applied following debridement, as required, and provided a stable base for secondary wound healing or skin grafting, as needed. Of the patients: 12 (54%) healed completely; one (4%) progressed towards complete vascularisation with the BTM in situ; two (9%) underwent major amputations despite successful application of the BTM to lower limb wounds; and one (4%) returned to theatre to have retained clips removed. The remaining six (27%) patients failed to heal completely following BTM application. Ischaemia, infection, vasculitis and underlying osteomyelitis were limiting factors in achieving limb salvage or healing. Declaration of interest: The authors have no conflicts of interest to declare.
Mentha piperita silver nanoparticle-loaded hydrocolloid film for enhanced diabetic wound healing in rats
Authors: Aftab Reema , Akbar Fatima , Afroz Amber , Asif Awais , Khan Muhammad Ramzan , Rehman Nazia , Zeeshan Nadia 
Published: March 2024

Objective: To investigate the role of Mentha piperita silver nanoparticle-loaded carbopol gel for enhanced wound healing in a diabetic rat model. This research further aims to explore bioactive compounds derived from Mentha piperita obtained from high altitude. Method: Methanolic extracts of Mentha piperita (MP), Mentha spicata (MS) and Mentha longifolia (ML) were used to synthesise silver nanoparticles (AgNP). AgNP synthesis was confirmed by ultraviolet–visible (UV-Vis) spectroscopy, X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR) and scanning electron microscopy (SEM). The antioxidant activity was assessed by 2, 2-diphenyl-1-picrylhydrazyl (DDPH) assay. Antiglycation potential was determined by measuring the fluorescent advanced glycation end products. The bioactive compound identified in the Mentha piperita methanolic (MPM) fraction through electrospray ionisation tandem mass spectrometric analysis (ESI-MS) was responsible for the highest antiglycation. The effects of MPM and MPM.AgNP-loaded Carbopol (Sanare Lab, India) on wound healing were compared in male, alloxan-induced, diabetic albino rats (200–250g), divided into control and treated groups. Effects on wound healing were assessed via histopathology. Results: UV-Vis and FTIR confirmed NP synthesis with peaks for flavonoids and polyphenols. SEM and XRD explored the cubical, 30–63nm crystalline NP. The maximum antioxidant and antiglycation potential was observed in order of; MP.AgNP>MS.AgNP>ML.AgNP. The highest antioxidant activity was observed by methanolic and aqueous MP.AgNPs (88.55% and 83.63%, respectively) at 2mg.ml-1, and (75.16% and 69.73%, respectively) at 1mg.ml-1, compared to ascorbic acid (acting as a positive control, 90.01%). MPM.AgNPs demonstrated the best antiglycation potential of 75.2% and 83.3% at 1mg.ml-1 and 2mg.ml-1, respectively, comparable to positive control (rutin: 88.1%) at 14 days post-incubation. A similar trend was observed for antimicrobial activity against Bacillus subtilis, Micrococcus luteus and Escherichia coli with an inhibition zone of 21mm, 21.6mm and 24.6mm. Rosmarinic acid was the active compound present in Mentha piperita, as identified by ESI-MS. MPM.AgNP-loaded Carbopol resulted in 100% wound closure compared with control at 20 days post-wounding. In the treatment group, re-epithelialisation was achieved by day 18, compared with 25 days for the positive control group. Conclusion: MPM.AgNP-loaded Carbopol demonstrated safer and more effective biological properties, hence accelerating the diabetic excision wound healing process in alloxan-induced diabetic rats.
SAHA TÜRKLERİNİN GELENEKSEL İNANÇ UNSURLARI İLE İLGİLİ BİLMECELER
Authors: ÇOLAK Doğan 
Published: March 2024

Toplumlar kültürlerini birden çok vasıta aracılığıyla geçmişten günümüzde aktarmışlardır. Yazının olmadığı dönemlerde bu kültür aktarımı görevini halk edebiyatı ürünleri üstlenmiştir. Bu ürünler arasında toplumsal bellekte yaygın yeri olan bilmeceler de önemli bir konumdadır. Masal, destan, efsane, fıkra, atasözü vb. çeşitli halk edebiyatı ürünlerinde olduğu gibi bilmeceler de ait olduğu toplumun kültürel kodlarını bünyelerinde barındırmaktadır. Söz konusu sözlü kültür ürününün ilk örneklerinin çok eski dönemlerde görülmüş olması dolayısıyla mitolojiyle ilgileri bulunmaktadır. Bu yönüyle bilmecelerde ait olduğu kültürün geleneksel inancı ile ilgili unsurları tespit etmek mümkündür. Zengin bir sözlü geleneğe sahip olan Saha Türklerinin bilmeceleri de içerisinde taşıdığı zengin malzemelerle inanç sistemine dair önemli bir tür olarak görülmektedir.
Bu çalışmada bilmece türü üzerine çeşitli araştırmacıların görüş ve tanımlarına yer verildikten sonra bilmecenin mitoloji ile ilişkisine yönelik genel bir değerlendirme yapılmıştır. Geleneksel Saha inanç sistemi hakkında da bilgilendirmenin yapıldığı çalışmanın inceleme bölümünde Saha Türklerinin geleneksel inancının bilmecelere yansımaları ele alınmıştır. Malzemenin tespit için Sardana Platonovna Oyunskaya tarafından 1975 yılında hazırlanan Saxa Taabırınnara “Saha Bilmeceleri” isimli eser taranmıştır. Konumuzla ilgili tespit edilen bilmeceler tarafımızdan Latin harflerine transkribe edilip Türkiye Türkçesine aktarılmıştır. Cevaplarına göre konu tasnifine tabi tutulan örnekler, ifade ettikleri anlam özelliklerine göre incelenmiştir. Bilmecelere dair bulgular sonuç bölümünde değerlendirilmiştir.
Scanning defocusing particle tracking for the experimental characterization of flows in demanding microfluidic systems
Authors: Galand Quentin , Blinder David , Gelin Pierre , Maes Dominique , De Malsche Wim 
Published: March 2024

A novel scanning particle image velocimetry technique, to the best of our knowledge, is
proposed to characterize flows in microfluidic applications.
Three-dimensional information is acquired by oscillating the target
sample over a fixed focal plane, allowing the reconstruction of
particle trajectories with micrometer accuracy over an extended depth.
This technology is suited for investigating acoustic flows with
unprecedented precision in microfluidic applications. In this
contribution, we describe the experimental setup and the data
processing pipeline in detail; we study the technique’s performance by
reconstructing pressure-driven flow; and we report the
three-dimensional trajectory of a 2 µm particle in an acoustic
flow in a 525µm×375µm microchannel with micrometric
accuracy.
Time to full enteral feeds in hospitalised preterm and very low birth weight infants in Nigeria and Kenya
Authors: Imam Zainab O. , Nabwera Helen M. , Tongo Olukemi O. , Andang’o Pauline E. A. , Abdulkadir Isa , Ezeaka Chinyere V. , Ezenwa Beatrice N. , Fajolu Iretiola B. , Mwangome Martha K. , Umoru Dominic D. , Akindolire Abimbola E. , Otieno Walter , Olwala Macrine , Nalwa Grace M. , Talbert Alison W. , Abubakar Ismaela , Embleton Nicholas D. , Allen Stephen J. ,   on behalf of the Neonatal Nutrition Network (NeoNuNet)
Published: March 2024

Background
Preterm (born < 37 weeks’ gestation) and very low birthweight (VLBW; <1.5kg) infants are at the greatest risk of morbidity and mortality within the first 28 days of life. Establishing full enteral feeds is a vital aspect of their clinical care. Evidence predominantly from high income countries shows that early and rapid advancement of feeds is safe and reduces length of hospital stay and adverse health outcomes. However, there are limited data on feeding practices and factors that influence the attainment of full enteral feeds among these vulnerable infants in sub-Saharan Africa.

Aim
To identify factors that influence the time to full enteral feeds, defined as tolerance of 120ml/kg/day, in hospitalised preterm and VLBW infants in neonatal units in two sub-Saharan African countries.

Methods
Demographic and clinical variables were collected for newborns admitted to 7 neonatal units in Nigeria and Kenya over 6-months. Multiple linear regression analysis was conducted to identify factors independently associated with time to full enteral feeds.

Results
Of the 2280 newborn infants admitted, 484 were preterm and VLBW. Overall, 222/484 (45.8%) infants died with over half of the deaths (136/222; 61.7%) occurring before the first feed. The median (inter-quartile range) time to first feed was 46 (27, 72) hours of life and time to full enteral feeds (tFEF) was 8 (4.5,12) days with marked variation between neonatal units. Independent predictors of tFEF were time to first feed (unstandardised coefficient B 1.69; 95% CI 1.11 to 2.26; p value <0.001), gestational age (1.77; 0.72 to 2.81; <0.001), the occurrence of respiratory distress (-1.89; -3.50 to -0.79; <0.002) and necrotising enterocolitis (4.31; 1.00 to 7.62; <0.011).

Conclusion
The use of standardised feeding guidelines may decrease variations in clinical practice, shorten tFEF and thereby improve preterm and VLBW outcomes.
The impact of maternal health on child’s health outcomes during the first five years of child’s life in countries with health systems similar to Australia: A systematic review
Authors: Mudiyanselage Shalika Bohingamu , Wanni Arachchige Dona Sithara , Angeles Mary Rose , Majmudar Ishani , Marembo Miriam , Tan Eng Joo , Price Anna , Watts Jennifer J. , Gold Lisa , Abimanyi-Ochom Julie 
Published: March 2024

Introduction
The first five years of life is an important developmental period that establishes the foundation for future health and well-being. Mothers play a primary role in providing emotional and physical nourishment during early childhood. This systematic review aims to explore the association between maternal health and child health in the first five years of the child’s life.

Materials and methods
As primary aims, we systematically synthesised published evidence relating to the first five years of life for associations between maternal health exposures (mental, physical and Health-Related Quality of Life (HRQoL) and child health outcomes (physical health, mental health, HRQoL and Health Service Use (HSU) /cost). As a secondary aim, we explored how the above associations vary between disadvantaged and non-disadvantaged populations. The search was limited to studies that published and collected data from 2010 to 2022. The systematic review was specific to countries with similar health systems to Australia. The search was conducted in MEDLINE, CINAHL, APA PsycINFO, GLOBAL HEALTH, and EMBASE databases. The quality of the included studies was assessed by The Effective Public Health Practice Project (EPHPP) tool.

Results
Thirteen articles were included in the final synthesis from the identified 9439 articles in the primary search. Six (46%) explored the association between maternal mental health and child’s physical health, two (15%) explored maternal and child’s physical health, one (8%) explored maternal and child’s mental health, one (8%) explored maternal physical health and child’s HRQoL, and three (23%) explored maternal mental health and child’s HSU. We found an association between maternal health and child health (physical and mental) and HSU outcomes but no association between maternal health and child’s overall HRQoL. The results for disadvantaged communities did not show any difference from the general population.

Discussion and conclusion
Our review findings show that maternal health influences the child’s health in the first five years. However, the current evidence is limited, and the findings were primarily related to a specific maternal or child’s health condition. There was no evidence of associations of child health outcomes in healthy mothers. There is an extensive research gap investigating maternal health exposures and child outcomes in quality of life and overall health.
Modified Mesenchymal stem cell, platelet-rich plasma, and hyaluronic acid intervention in early stage osteoarthritis: A systematic review, meta-analysis, and meta-regression of arthroscopic-guided intra-articular approaches
Authors: Tjandra Kevin Christian , Novriansyah Robin , Sudiasa I. Nyoman Sebastian , Ar Ardiyana , Rahmawati Nurul Azizah Dian , Dilogo Ismail Hadisoebroto 
Published: March 2024

Background
Mesenchymal stem cells (MSCs) hold promise for osteoarthritis (OA) treatment, potentially enhanced by combining them with platelet-rich plasma (PRP) and hyaluronic acid (HA). This study aimed to assess the synergy of MSCs, PRP, and varying HA doses, and determine optimal MSC sources to treat early-stage OA in the perspective of Lysholm score, VAS Score, KSS score, and WOMAC score.

Method
Original articles from 2013 to 2023 were screened from four databases, focusing on clinical trials and randomized controlled trials. The Risk of Bias in Non-randomized Studies—of Interventions (ROB-2) tool evaluated bias, and a PICOS criteria table guided result construction. Revman 5.4 analyzed outcomes such as Lysholm score, VAS score, KSS, WOMAC score, cartilage volume, and defect size using MRI. This systematic review adhered to PRISMA guidelines.

Result
Nine studies met the final inclusion criteria. Meta-analysis revealed a significant improvement in Lysholm score (MD: 17.89; 95% CI: 16.01, 19.77; I2 = 0%, P = 0.56), a notable reduction in VAS score (MD: -2.62; 95% CI: -2.83, -2.41; I2 = 99%, P < 0.00001), elevated KSS (MD: 29.59; 95% CI: 27.66, 31.52; I2 = 95%, P < 0.0001), and reduced WOMAC score (MD: -12.38; 95% CI: -13.75, -11.01; I2 = 99%, P < 0.0001).

Conclusions
Arthroscopic guided high-dose subchondral application of primary cultured synovial MSCs in popliteal PRP media with HA effectively regenerates cartilage defects and improves clinical outcomes in early-stage osteoarthritis. Clarification of MSC sources and quantities enhances the understanding of this promising treatment modality.