bluuebunny/crossref_metadata_2025_split huggingface dataset:
Assembling of a cost-effective and adaptable motorised rodent exercise wheel
Authors: R Reshmi , V Suganthi , S Rajaram , K Malleshappa 
Published: March 2024

Objectives:
Exercise physiology is one of the leading branches of applied physiology. It is concerned with studies related to the effect of acute and chronic exercise on mental and physical health research in human subjects and animals. There are various methods of physical exercise which have been used in animal studies including rodents. However, the machines available for research purposes are sophisticated and expensive, which also requires an additional annual maintenance cost. The objective is to assemble an efficient, reliable, cost-effective, and humane motorized exercise wheel setup for the study of acute and chronic physical exercise in rodents.

Materials and Methods:
The motorized rodent exercise wheel was assembled using affordable locally available materials.

Results:
A cost-effective, efficient model for rodent exercise was built and the total cost of this setup was 32 USD or 2860 INR only.

Conclusion:
This cost-effective rodent exercise wheel works efficiently for the conduction of exercise-related studies in rodents.
Molecular epidemiology of Carbapenemase-encoding genes and comparative evaluation of carbapenem MIC with genotypic carbapenem resistance in Klebsiella isolates from neonatal sepsis cases
Authors: Gangar Seema , Singh Narendra Pal , Goyal Nisha , Mohapatra Subhashree , Das Shukla , Batra Prerna 
Published: March 2024

Objectives:
The objective of this study was to determine the molecular epidemiology of Carbapenemase-encoding genes in Klebsiella isolates from neonatal sepsis cases and comparative evaluation of carbapenem minimum inhibitory concentration (MIC) with genotypic carbapenem resistance.

Materials and Methods:
One hundred cases of neonatal sepsis with blood cultures positive for Klebsiella spp. were included in the study. MIC for imipenem and meropenem was determined by Epsilometer-test. Antimicrobial susceptibility testing (AST) was performed by modified Kirby Bauer disc diffusion method. All the isolates of Klebsiella spp. were tested for the presence of beta-lactamase Klebsiella pneumoniae carbapenemase (blaKPC ), beta-lactamase New Delhi metalloβ-lactamase-1(blaNDM-1), beta-lactamase imipenemase (blaIMP), beta-lactamase Verona imipenemas e (blaVIM) genes by multiplex polymerase chain reaction (PCR) and uniplex PCR for beta-lactamase oxacillinase-48 (blaOXA-48). Comparison of individual antibiotic susceptibility between carbapenemase-encoding gene positive and negative Klebsiella spp. isolates was performed.

Statistical analysis:
Statistical analysis was done using the Fisher’s exact test. P < 0.05 was considered significant.

Results:
The prevalence of carbapenemase-encoding genes in Klebsiella spp. was 16%. Most predominant carbapenemase-encoding gene was blaOXA-48 gene (12%) followed by blaNDM-1 gene (6%). Coexpression of both blaOXA-48 and blaNDM-1 was observed in 2% of isolates. All the Klebsiella spp. isolates harboring the carbapenemases gene (100%) had resistant MIC values for Meropenem, whereas, for imipenem, only 75% of isolates had resistant MIC values.

Conclusions:
Determination of prevalence of carbapenemase-encoding genes is of paramount importance in the development of effective antibiotic policies at various levels.
Aplikasi Pemberian Kolostrum terhadap Percepatan Pelepasan Tali Pusat
Authors: Kandari Nahira , Wardani Hasbiah 
Published: March 2024

Background: Colostrum is breast milk for postpartum mothers which is released at the beginning of labor until the 3rd day after the baby is born. It is very important to be given in the first life of the baby because it contains immune substances, especially immunoglobulin (IgA) which can protect babies from infectious diseases. Giving colostrum by applying to the umbilical cord care. Purpose: To determine the effect of the application of colossal distribution on the acceleration of the release of the umbilical cord at the Bara-Baraya Makassar Health Center.Methods: This study used a quasy experimental method with a posttest only control design. The total population in this study were all newborn babies at the Bara-Baraya Makassar Health Center from August to October 2020 as many as 32 babies. Based on these data, the samples in this study were 30 newborns according to the inclusion criteria.Results: Research conducted at the Bara-Baraya Makassar Health Center in 2020 found that from 30 respondents, the average time to release the umbilical cord using colostrum was 5 days. Whereas in the Dry Open group the average time to release the umbilical cord was 6.40 days. The results of the analysis using the Mann Whitney Statistical Test showed the results (ρ-value 0.001). Conclusion: Colostrum administration accelerates the release of the umbilical cord in newborns. It is important to be implemented in the care of newborns and to educate mothers who give birth.Latar Belakang: Kolostrum merupakan ASI ibu postpartum yang dikeluarkan pada awal persalinan sampai dengan hari ke-3 setelah bayi lahir. Ia sangat penting untuk diberikan pada kehidupan pertama bayi karena mengandung zat kekebalan terutama Immunoglobulin (IgA) yang dapat melindungi bayi dari penyakit-penakit infeksi. Pemberian kolostrum dengan mengoleskan pada perawatan tali pusat. Tujuan: Untuk mengetahui pengaruh aplikasi pemberian kolosrtum terhadap percepatan pelepasan tali pusat di Puskesmas Bara-Baraya Makassar.Metode: Penelitian ini menggunakan metode quasy eksperimen dengan rancangan posttest only control design. Jumlah populasi dalam penelitian ini adalah semua bayi baru lahir di Puskesmas Bara-Baraya Makassar mulai Agustus-Oktober 2020 sebanyak 32 Bayi. Berdasarkan data tersebut yang menjadi sampel dalam penelitian ini adalah sebanyak 30 Bayi Baru Lahir yang sesuai dengan kriteria Inklusi. Hasil: Penelitian yang di lakukan di Puskesmas Bara-Baraya Makassar Tahun 2020 didapati dari 30 Responden, rata – rata waktu pelepasan tali pusat dengan menggunakan Kolostrum adalah 5 hari. Sedangkan pada kelompok kering terbuka rata-rata waktu pelepasan tali pusat adalah 6,40 hari. Hasil Analisis dengan Uji Statistik Mann Whitney didapatkan hasil (ρ-value 0,001). Simpulan: Pemberian kolostrum mempercepat pelepasan tali pusat pada bayi baru lahir. Ia penting diimplementasikan dalam asuhan perawatan bayi baru lahir dan melakukan edukasi kepada ibu bersalin
Motivasi Suami dan Paritas Mempengaruhi Kecemasan Ibu Hamil Menjelang Persalinan
Authors: Dinopawe Asriaty , Makatita Bazrul , Alerbitu Kharisma Lestina 
Published: March 2024

Background: Anxiety before delivery can cause the birth process to take a long time and bleeding occurs. Maternal anxiety is influenced by family support in this case husband and parents. Primarily pregnant women who get support from their families can reduce anxiety. Purpose: To determine the effect of the husband's motivation and parity on the anxiety of pregnant women before delivery. Methods: This study used a cross-sectional study design. The population and sample in this study were 32 pregnant women using the total sampling technique. The tool used for data collection is a questionnaire consisting of questions related to motivation, parity, and anxiety. Data analysis using univariate and bivariate with Fisher exact test. Results: The results showed that there was an influence between motivation and parity on anxiety before delivery (p = 0.001). Conclusion: Husband's motivation reduces anxiety in pregnant women before delivery and multiparous women have less anxiety than primiparous women. The role of the husband in motivating and providing strengthening for maternity mothers needs to be increased by pregnant women before delivery, especially for primiparous mothers, so that maternal anxiety can be minimized and childbirth can be normal without complications.AbstrakLatar Belakang: Kecemasan menjelang persalinan dapat menyebabkan proses kelahiran bayi berlangsung lama dan terjadi perdarahan. Kecemasan ibu bersalin dipengaruhi oleh dukungan keluarga dalam hal ini suami dan orang tua. Ibu hamil primi yang mendapatkan dukungan dari keluarga dapat mengurangi kecemasan. Tujuan: Mengetahui pengaruh motivasi suami dan paritas terhadap kecemasan ibu hamil menjelang persalinan. Metode: Studi ini menggunakan rancangan studi cross sectional. Populasi dan sampel dalam penelitian ini adalah ibu hamil yang berjumlah 32 orang dengan menggunakan teknik total sampling. Alat yang digunakan untuk pengumpulan data adalah kuesioner yang terdiri dari pertanyaan-pertanyaan terkait motivasi, paritas dan kecemasan. Analisis data menggunakan univariat dan bivariat dengan fisher ecaxt test. Hasil: Hasil penelitian diperoleh ada pengaruh antara motivasi dan paritas terhadap kecemasan menjelang persalinan (p= 0,001). Simpulan: Motivasi suami mengurangi kecemasan pada ibu hamil menjelang persalinan dan ibu multipara memiliki kecemasan yang kurang dibandingkan ibu primipara. The husband's role in motivating and providing strengthening for mothers facing childbirth needs to be increased, especially for primiparous mothers, so that maternal anxiety can be minimized and childbirth can be normal without complications.
Efek Pemberian Massage Effleurage Mampu Meningkatkan Produksi Air Susu Ibu pada Ibu Nifas
Authors: Rinjani Margareta , Apriyani Magdalena Tri Putri 
Published: March 2024

Background: The problem with the target of the exclusive breastfeeding program has not yet reached the global target due to the factor that mothers who give birth think that breastfeeding has not been smooth. The solution can be done with non-pharmacological therapy, oxytocin massage, effleurage massage, by involving and supporting the husband. Purpose: This study was to examine the effect of oxytocin massage through effleurage massage on breast milk production in postpartum mothers. Methods: Quasi experimental with nonequivalent control group as the design of this study. The treatment group was 17 normal postpartum pregnant women and 17 control groups. The treatment group after 6-8 hours postpartum was given effleurage massage on the back using olive oil for 3-5 minutes. Data analysis using Mann-Whitney test. Results: The results showed that there was an effect before and after effleurage massage was carried out in the experimental and control groups, namely (p = 0.002). Conclusion: Non-pharmacological therapy with oxytocin massage through effleurage massage was able to increase the amount of milk production by involving and supporting the husband.Latar belakang: Masalah target program pemberian ASI (Air Susu Ibu) eksklusif masih belum mencapai target global disebabkan oleh faktor ibu bersalin menganggap ASI belum lancar. Solusi dapat dilakukan dengan terapi nonfarmakologi pijat oksitosin massage effleurage dengan melibatkan dan dukungan suami. Tujuan: Studi ini untuk mengkaji pengaruh pijat oksitosin melalui massage effleurage terhadap produksi ASI pada ibu postpartum. Metode: Quasi eksperimental dengan nonequivalent control group sebagai rancangan studi ini. Kelompok perlakuan adalah ibu hamil postpartum normal berjumlah 17 dan kelompok kontrol 17 orang. Kelompok perlakuan setelah postpartum 6-8 jam diberikan massage effleurage di bagian punggung dengan menggunkan minyak zaitun selama 3-5 menit. Analisis data menggunakn Uji Mann-whitney. Hasil: Hasil menunjukkan terdapat pengaruh sebelum dan sesudah dilakukan massage effleurage pada kelompok eksperimen dan kontrol yaitu (p=0,002). Simpulan: Terapi nonfarmakologi dengan pijat oksitosin melalui massage effleurage mampu meningkatkan jumlah produksi ASI dengan melibatkan dan dukungan suami. w:LsdException L
Terapi Herbal Jinten Hitam dalam Peningkatan Haemoglobin pada Ibu Menyusui dengan Anemia
Authors: Septiani Ranny , Nurchairina Nurchairina , Trinovadela Nora Isa , Herlina Herlina 
Published: March 2024

Background: One of the world's health problems in developing countries is anemia. Nationally, anemia is common in women. Anemia is very dangerous for both mother and baby. Anemia in breastfeeding mothers will affect the quality of breast milk so that it affects the nutritional fulfillment of their babies. Purpose: To determine the effectiveness of giving black cumin to breastfeeding mothers with anemia in Bandar Lampung City in 2020. Methods: This study is a quasi-experimental study with pre and post-test designs. The treatment in this study was giving black cumin. While the variables to be studied are hemoglobin levels in the blood of breastfeeding mothers before and after the intervention. The sample in this study was breastfeeding mothers who suffered from anemia in Bandar Lampung City. Bivariate data analysis used the T-test to determine the difference in hemoglobin levels before and before offering black cumin. Results: This study showed that the administration of black cumin had an average hemoglobin level before administration of black cumin the average hemoglobin level after administration of black cumin (p=0,001), resulting in an increase in the average hemoglobin level of 1.84 dl/gr. Conclusion: The use of black cumin as an effective complementary therapy (complementary) in the treatment of anemia in lactating mothers with anemia.Abtrstark. Latar Belakang : Salah satu masalah kesehatan di dunia pada negara berkembang adalah anemia. Secara nasional anemia banyak terjadi pada perempuan.Anemia sangat berbahaya bagi ibu dan bayinya. Anemia pada ibu menyusui akan mempengaruhi kualitas ASI sehingga mempengaruhi pemenuhan nutrisi bayinya.Tujuan : mengetahui efektifitas pemberian jinten hitam pada ibu menyusui dengan anemia di Kota Bandar Lampung tahun 2020. Metode: Penelitian ini merupakan penelitian quasi eksperimendengan desain pre dan post test. Perlakuan dalam penelitian ini adalah pemberian jinten hitam. Sedangkan variabel yang akan diteliti adalah kadar hemoglobin dalam darah ibu menyusui sebelum dan setelah diintervensi. Sampel pada penelitian adalah ibu meyusui yang menderita anemia di Kota Bandar Lampung. Analisis data bivariat menggunakan uji T untuk mengetahui beda kadar haemoglobin sebelum dan sesudah pemberian jinten hitam. Hasil : Penelitian ini didapat hasil pemberian jinten hitam mempunyai nilai rata-rata kadar hemoglobin sebelum pemberian jinten hitam rata-rata kadar hemoglobin setelah pemberian jinten hitam (p=0,001). Sehingga, terjadi peningkatan rata-rata kadar hemoglobin sebesar 1,84 dl/gr.. Simpulan: Penggunakan jinten hitam efektif sebagai terapi komplementer (pelengkap) dalam pengobatan anemia pada ibu menyusui dengan anemia.
Peningkatan Ekspresi Matrix Metalloproteinase-9 Ligamentum Sacrouterina dan Otot Levator Ani Postpartum Rattus Norvegicus
Authors: Ariani Novida 
Published: March 2024

Background: Vaginal delivery is a risk factor for pelvic organ prolapse. The biomolecular mechanism that links it is still unclear, thought to be through Matrix Metalloproteinase 9 (MMP-9). Purpose: This study aims to determine the increase in MMP-9 in the supporting tissues of the pelvic organs, especially the sacrouterine ligament and levator ani muscles in the postpartum period. Methods: This study was an observational cohort study on 5 female rats of Rattus norvegicus Wistar strain. Which were divided into nulliparous groups, postpartum day 1, day 3, and day 7. MMP-9 expression was calculated and analyzed using ANOVA. Results: There was a significant difference (p=0.01) of MMP-9 expression in the sacrouterine ligament between nulliparous rats, postpartum day 1, day 3, and day 7. There was also a significant difference (p=0.00) levator ani muscle MMP-9 expression between nulliparous rats, postpartum day 1, day 3, and day 7. There was a trend of increasing MMP-9 expression on the 1st to 3rd day postpartum, then decreasing gradually on the 7th day. Conclusion: Delivery changes the expression of MMP-9 in pelvic floor tissues such as the sacrouterine ligament and levator ani muscle and these changes are time-dependent.Abstrak. Latar Belakang: Persalinan pervaginam merupakan faktor resiko prolaps organ panggul. Mekanisme biomolekuler yang menghubungkannya masih belum jelas, diduga melalui perantaraan Matriks Metalloproteinase 9 (MMP-9). Tujuan: Penelitian ini bertujuan untuk mengetahui peningkatan MMP-9 pada jaringan penyokong organ panggul, terutama ligamentum sacrouterina dan otot levator ani periode post partum. Metode: Penelitian ini adalah studi observational cohort pada 5 tikus betina Rattus norvegicus strain Wistar. Yang terbagi menjadi kelompok nullipara, postpartum hari ke-1, hari ke-3 dan hari ke-7.. Preparat jaringan ligamentum sacrouterina dan otot levator ani diwarnai dengan imunohistokimia. Ekspresi MMP-9 dihitung dan dianalisa dengan menggunakan ANOVA. Hasil: Terdapat perbedaan yang signifikan (p=0,01) ekspresi MMP-9 pada ligamentum sacrouterina antara tikus nullipara, postpartum hari ke-1, hari ke-3, dan hari ke-7. Terdapat pula perbedaan yang signifikan (p=0,00) ekspresi MMP-9 otot levator ani antara tikus nullipara , postpartum hari ke-1, hari ke-3, dan hari ke-7. Tampak tren peningkatan ekspresi MMP-9 pada hari ke-1 hingga ke-3 postpartum, selanjutnya menurun bertahap pada hari ke-7. Simpulan: Persalinan mengubah ekspresi MMP-9 pada jaringan dasar panggul seperti ligamentum sacrouterina dan otot levator ani dan perubahan ini bersifat time-dependently.
The Anxiety of Midwifery Students in Clinical Practice at Health Service Facilities during the Covid-19 Pandemic
Authors: Fatsena Rizka Adela , Kartikasari M. Nur Dewi , Megasari Anis Laela 
Published: March 2024

Background: The Covid-19 pandemic is the most important problem currently faced by all health organizations and governments in the world. Furthermore, it seriously affects the mental state of individuals in various circles of society, including health students, specifically in midwifery. The role of midwifery students experiencing clinical practice during a pandemic increases their vulnerability to anxiety and stress. Therefore, this descriptive study aims to determine the anxiety level of midwifery students in carrying out clinical practice during the Covid-19 pandemic. This study was conducted to determine the anxiety level of midwifery students in carrying out clinical practice during the Covid-19 pandemic. Methods: Total sampling was performed using the Hamilton Anxiety Rating Scale (HARS), a measuring instrument presented as an electronic questionnaire through a google form. Results: The results showed a relationship between the anxiety levels of midwifery students carrying out clinical practice at health service facilities during the Covid-19 pandemic (p-value 0.01).Conclusion: The Diploma-3 Midwifery students had anxiety in experiencing clinical practice during the Covid-19 pandemic because they are meant to interact directly with patients having various signs and symptoms.Latar Belakang: Pandemi Covid-19 dapat menyebabkan masalah kesehatan mental yang serius di berbagai kalangan masyarakat termasuk mahasiswa kesehatan khususnya kebidanan. Mahasiswa kebidanan berperan penting dalam menjalani praktik klinik saat terjadi pandemi, akan tetapi mereka lebih rentan terhadap kecemasan dan stres. Tujuan: Penelitian ini bertujuan untuk mengetahui tingkat kecemasan mahasiswa kebidanan dalam melaksanakan praktik klinik pada saat pandemi Covid-19. Penelitian ini merupakan penelitian Cross Sectional Study. Populasi dalam penelitian ini adalah mahasiswa kebidanan yang menjalankan praktik klinik pada saat pandemi Covid 19. Metode: Pengambilan sampel dilakukan dengan total sampling dengan menggunakan alat ukur kecemasan Hamilton Anxiety Rating Scale (HARS) yang disajikan dalam bentuk kuesioner elektronik melalui formulir google. Hasil: Hasil penelitian ini menunjukkan bahwa hubungan kecemasan mahasiswa kebidanan dalam praktik klinik di pelayanan kesehatan selama masa pandemi Covid-19 (p value 0,01). Simpulan: Kecemasan Mahasiswa Kebidanan dalam praktik klinik di Pelayanan Kesehatan selama masa Pandemi Covid-19 karena mahasiswa berinteraksi langsung dengan pasien yang memilik beragam tanda dan gejala.
Efek Pelatihan dengan Metode Pembelajaran Discovery Learing Meningkatkan Kemampuan Kader tentang Pemberian Makanan Bayi dan Anak Balita
Authors: Sudarmi Sudarmi 
Published: March 2024

Latar Belakang: Upaya agar kader dapat menyampaikan informasi pada masyarakat tentang pentinynya Pemberian Makan pada Bayi dan Anak (PMBA) secara maksimal. Perlu diberikan pelatihan pada kader dengan metode pembelajaran yang aktif, yaitu discovery learning yang dapat mempercepat pemahaman atau peningkatan pengetahuan dan ketrampilan. Tujuan: Untuk mengkaji efektivitas pelatihan dengan metode discovery learning terhadap pengetahuan dan keterampilan penyuluhan kader tentang PMBA. Metode: Penelitian menggunakan rancangan quasi eksperimen dengan nonequivalent control group design dan pos test -only control group design. Penelitian dilakukan dengan memberikan pelatihan pada kader dengan menggunakan metode discovery learning pada bulan Juni-Oktober 2022 di Puskesmas Karang anyar Kabupaten Lampung Selatan. Jumlah sampel 60 kader. Analisis data bivariat menggunakan uji T-Test Independen. Hasil: Hasil analisis uji statistik menunjukkan ada perbedaan (lebih efektif) metode discovery learning dibandingkan metode konvensional dalam meningkatkan pengetahuan dan keterampilan penyuluhan kader tentang PMBA (p-value 0,001). Simpulan: Percepatan peningkatan pengetahuan dan ketrampilan memberikan penyuluhan kader tentang PMBA dengan metode discovery learning dapat menjadi pilihan bagi tenaga kesehatan, karena lebih efektif.

Abstrac. The Effect of Training with the Discovery Learning Learning Method Increases Health Worker' (Kader) in Abilities about feeding Infants and Toddlers
Background: Efforts for health worker to convey information to the public about the importance of optimal feeding of infants and children. It is necessary to provide training to health worker with active learning methods, namely discovery learning which can accelerate understanding or increase knowledge and skills. Purpose: To examine the effectiveness of training using the discovery learning method on knowledge and counseling skills regarding feeding infants and children. Methods: The study used a quasi-experimental design with a nonequivalent control group design and post-test -only control group design. The research was conducted by providing training to health worker using the discovery learning method in June-October 2022 at the Karang Anyar Community Health Center, South Lampung Regency. The number of samples is 60 health worker. Bivariate data analysis used the Independent T-Test. Results: Statistical test analysis showed that there was a difference (more effective) with the discovery learning method compared to conventional methods in increasing the knowledge and skills of health worker in counseling about feeding infants and children (p-value 0,001). Conclusion: Accelerating the increase in knowledge and skills in providing counseling to health worker about IYCF with the discovery learning method can be an option for health workers, because it is more effective.