bluuebunny/crossref_metadata_2025_split huggingface dataset:
Relativistic correlating basis sets for actinide atoms from 90Th to 103Lr
Authors: Noro Takeshi , Sekiya Masahiro , Osanai You , Koga Toshikatsu , Matsuyama Hisashi 
Published: May 2007

AbstractFor 14 actinide atoms from 90Th to 103Lr, contracted Gaussian‐type function sets are developed for the description of correlations of the 5f, 6d, and 7s electrons. Basis sets for the 6d orbitals are also prepared, since the orbitals are important in molecular environments despite their vacancy in the ground state of some actinides. A segmented contraction scheme is employed for the compactness and efficiency. Contraction coefficients and exponents are so determined as to minimize the deviation from accurate natural orbitals of the lowest term arising from the 5fn−16d17s2 configuration. The spin‐free relativistic effects are considered through the third‐order Douglas‐Kroll approximation. To test the present correlating sets, all‐electron calculations are performed on the ground state of 90ThO molecule. The calculated spectroscopic constants are in excellent agreement with experimental values. © 2007 Wiley Periodicals, Inc. J Comput Chem, 2007
Association between vitamin‐D receptor gene FokI polymorphism and Graves' disease among Taiwanese Chinese
Authors: Chen Rong‐Hsing , Chang Chwen‐Tzuei , Chen Huey‐Yi , Chen Wen‐Chi , Tsai Chang‐Hai , Tsai Fuu‐Jen 
Published: May 2007

Abstract1,25(OH)2D3, exerting its biological effects through the vitamin‐D receptor (VDR), plays a role in the modulation of the human immune system. The aim of this study was to test for the presence of an association between VDR gene polymorphism and the susceptibility to Graves' disease (GD) for Taiwanese Chinese. Using a polymerase chain reaction (PCR)‐based restriction analysis, we screened the VDR exon 2 start codon T/C (VDR‐FokI) polymorphism to determine the genotypes for 88 GD patients and 90 normal controls. From the genotype analysis, GD patients featured a greater proportion of the CC genotype (44.3%) and a smaller proportion of the TT genotype (12.5%) than was the case for normal controls (CC: 23.3% and TT: 28.9%; chi‐squared test, P=0.003). The odds ratios (ORs) for the risk of the CC genotype's appearance compared with the corresponding values for the TT and TC genotypes, for the GD patient group, were, 4.39 (95% confidence interval [CI]: 1.82–10.61) and 2.10 (95% CI: 1.06–4.18), respectively. With respect to the allelic analysis, we observed significantly increased C‐allele (65.9%) and decreased T‐allele (34.1%) frequencies among GD patients compared to normal controls (C: 47.2% and T: 52.8%; chi‐squared test, P=0.002). The OR for the risk of appearance of the C allele in the GD‐patient group was 1.93 (95% CI: 1.27–2.95). In conclusion, the VDR‐FokI T/C polymorphism might be able to be used as a genetic marker to predict the likelihood of GD development. J. Clin. Lab. Anal. 21:173–177, 2007. © 2007 Wiley‐Liss, Inc.
Elevation of CA 19‐9 and chromogranin A, in addition to CA 125, are detectable in benign tumors in leiomyomas and endometriosis
Authors: Tsao Kuo‐Chien , Hong Ji‐Hong , Wu Tsu‐Lan , Chang Pi‐Yueh , Sun Chien‐Feng , Wu James T. 
Published: May 2007

AbstractAs the best‐known tumor marker for ovarian carcinoma, CA 125 has also been commonly used to monitor patients with common benign gynecologic diseases such as endometriosis and leiomyoma. Both of these benign tumors are known to be at risk of developing into cancer. During the screening of an asymptomatic population with multiple tumor markers, including alpha‐fetoprotein (AFP), carcinoembryonic antigen (CEA), prostate‐specific antigen (PSA), CA 125, CA 19‐9, CA 15‐3, chromogranin A (CgA), and squamous cell carcinoma antigen (SCC), we have detected elevated tumor markers in 142 individuals; 19 of them were diagnosed with endometriosis or leiomyoma or both. In addition to the detection of elevation of CA 125 in these benign tumors, elevated CA 19‐9 or CgA was also found in these patients with endometriosis or leiomyoma. Many patients only had elevated CA 19‐9 or CgA; the elevation of CA 125 was not detected. It appears that instead of monitoring only CA 125, as is traditionally done, multiple tumor markers, including CA 19‐9, CgA, and CA 125, should be measured simultaneously in women with clinical disorders associated with the ovary or uterus in order to detect gynecologic benign tumors and in order to prevent further development of cancer. J. Clin. Lab. Anal. 21:193–196, 2007. © 2007 Wiley‐Liss, Inc.
Relationship of serum adiponectin with blood lipids, HbA1c, and hs‐CRP in type II diabetic postmenopausal women
Authors: Goodarzi Mohammad Taghi , Babaahmadi‐Rezaei Hossein , Kadkhodaei‐Eliaderani Manizheh , Haddadinezhad Shahram 
Published: May 2007

AbstractAdipose tissue has been considered an important endocrine organ. Adiponectin secretes from adipose tissue and plays an important role in the regulation of glycemia, β‐oxidation in muscle, and decreased insulin resistance in the liver. The objectives of this study were to compare the levels of adiponectin, hs‐C‐reactive protein (CRP), HbA1c, and blood lipids among diabetic and healthy postmenopausal women, and to determine the relationship between circulating adiponectin and development of type II diabetes. This case‐control study was performed on 28 diabetic and 42 age‐matched healthy women. All participants were postmenopausal. Serum adiponectin concentrations, serum triglycerides (TG), cholesterol, low‐density lipoprotein cholesterol (LDL‐C), and high‐density lipoprotein cholesterol (HDL‐C) concentrations were determined. Blood HbA1c and serum hs‐CRP were also measured. Adiponectin levels were significantly decreased (P<0.01) in the diabetic patients as compared to normal control subjects. Adiponectin levels were negatively associated with hs‐CRP, LDL‐C, HbA1c, TG, and total cholesterol (TC). A positive correlation was observed between adiponectin and HDL‐C. The obtained data indicate that diabetic women have lower adiponectin levels compared to healthy women. HbA1c as an indicator of glycemic control has a negative correlation with serum adiponectin. Adiponectin may play an important role in the pathogenesis of diabetes, and may be an independent predictor of the development of diabetes in women. J. Clin. Lab. Anal. 21:197–200, 2007. © 2007 Wiley‐Liss, Inc.
Rapid detection of the UGT1A1 single nucleotide polymorphism G211A using real‐time PCR with Taqman minor groove binder probes
Authors: Wong Fei‐Liang , Wang May‐Kay , Boo Nem‐Yun , Hamidah N.H. , Othaman Ainoon B. 
Published: May 2007

AbstractThe UGT1A1 Taqman MGB probe single nucleotide polymorphism (SNP) genotyping assay was developed to detect nucleotide 211 of the UDP‐glucoronocyltransferase 1A1 (UGT1A1) gene. Defects in this enzyme interfere with process of conjugation of bilirubin and cause unconjugated hyperbilirubinemia. Variation at nucleotide 211 in the coding region of the UGT1A1 gene has been shown to be prevalent in Japanese and Chinese. Using an ABI sequence detection system (SDS) 7000, an allele‐specific real‐time PCR‐based genotyping method was established to detect nucleotide G211A. Cord blood from 125 infants without hyperbilirubinemia (controls) were compared with cord blood from 74 infants (cases) with severe hyperbilirubinemia (total serum bilirubin >300µmol/L). Homozygous variation of the UGT1A1 gene at nucleotide 211(A/A) is significantly more common in cases (14.9%) than in controls (0.8%) (P<0.001). Direct sequencing from 20 randomly selected samples showed eight samples with homozygous wild type, seven with homozygous variant, and five samples were heterozygous. The result from this assay was in complete concordance with the DNA sequencing result and clearly discriminate wild‐type (G/G), homozygous variant (A/A), and heterozygous (G/A). This assay is rapid and robust for screening of SNP G211A to determine if this polymorphism plays a role in causing severe neonatal jaundice in the local context. J. Clin. Lab. Anal. 21: 167–172, 2007. © 2007 Wiley‐Liss, Inc.
High‐molecular intestinal alkaline phosphatase by agarose gel electrophoresis
Authors: Ooi Kinue , Shiraki Katsuya , Morishita Yoshitaka , Nobori Tsutomu 
Published: May 2007

AbstractThe presence of high‐molecular intestinal ALP (HIALP) overlapping with bone ALP in the α2β region has been demonstrated. In this study we evaluated a method of separating HIALP after its conversion into ALP5 by the action of protease. Serum samples from patients were mixed with protease at a ratio of 5:1 and left at room temperature for more than 30 min. The protease‐treated and nontreated samples were both subjected to agarose gel electrophoresis. Patients who showed a decrease in ALP3 in the α2β region and an increase in ALP5 in the β region were regarded as HIALP‐positive. HIALP was observed in 26.7–33.1% of patients with liver diseases, collagen diseases, and diabetes mellitus. Renal disease was ABO blood group‐dependent and showed high positive rates for blood groups B and O. The HIALP‐positive rate was low (7.1–15.5%) in patients with cardiovascular diseases, malignant tumors, and other disorders. ALP5 was also observed in 98.4% of HIALP‐positive patients with liver diseases. In patients with collagen diseases or diabetes mellitus, the positive rate of ALP5 was 40.4–66.7%. In conclusion, this method, in which HIALP is converted into ALP5 by protease pretreatment and is separated from bone ALP, allows HIALP to be identified while other fractions remain unaffected. J. Clin. Lab. Anal. 21:140–146, 2007. © 2007 Wiley‐Liss, Inc.
On the computational complexity of the minimum‐dummy‐activities problem in a pert network
Authors: Syslo Maciej M. 
Published: May 2007

AbstractThe scheduling and planning of a project can be represented by two types of networks, namely, by the activity networks and the event networks. For each project, there exists a unique activity network without redundant (transitive) arcs but since there is an infinite number of different‐sized event networks, the problem is to find an event network with the minimum number of dummy activities. Krishnamoorthy and Deo proved that this problem is NP‐complete. In Sections III and IV we characterize those activity networks which have event networks without dummy activities and present a polynomial‐time algorithm which tests if a given activity network requires dummy activities in the event network. The same result is also proved for a generalization of the real‐world problem to arbitrary digraphs. Finally, we present an example which shows that the number of nodes and the number of arcs in event networks cannot be minimized simultaneously.
Algorithms for finding paths with multiple constraints
Authors: Jaffe Jeffrey M. 
Published: May 2007

AbstractLet G = (V, E) be a graph with weight function w:E rightarrow Z+ and length function l:E /rightarrow Z+. The problem of determining for v1, V2 /in V whether there is a path from v1 to v2 with weight at most W and length at most L is NP‐complete. This paper gives two approaches to meeting or approximating the length and weight constraints. The first approach is to use a pseudopolynomial‐time algorithm which determines whether a path meets the constraints. Its running time is O (n5 b log nb) where n = |V| and b is the largest length or weight. If tables with O (n3b) entries are kept then all instances of multiple constraints may be decided. Table size may be substantially decreased if one is willing to tolerate incorrect answers to rare instances. The algorithm is suitable for distributed execution. In the second approach, an objective function is defined which evaluates a path's distance from meeting the constraints. Polynomial‐time algorithms attempt to find good paths in terms of the objective function. One algorithm is at most 1.62 times worst than optimal. A notion of “average worst‐case behavior” is defined. The algorithm's “average” behavior is 1.51 times worse than optimal.
Sorting algorithms for the implementation of a generalized vector product
Authors: Garcia‐Diaz Alberto , Friesen Donald K. , Bagert Donald J. 
Published: May 2007

AbstractThis article presents two sorting procedures with computational complexity O(nk2 log(k)) and O(nk2) to perform the generalized vector product A 1⊗ A2⊗ ⃛ ⊗ An, where each vector Ai has k distinct elements arranged in strictly increasing order. The vector product identifies the k minimal sums, each sum being defined as having one addend from each vector.
Optimal dynamic routing in communication networks with continuous traffic
Authors: Hajek Bruce , Ogier Richard G. 
Published: May 2007

AbstractNew characterizations of optimal state‐dependent routing strategies are obtained for the continuous traffic network model proposed by Segall for linear cost with unity weighting at each node and for constant inputs. The concept of flow relaxation is introduced and is used t o transform the optimal routing problem into an initial flow optimization problem with convex cost and linear constraints. Three algorithms are given for open‐loop computation of the optimal initial flow. The first is a simple iterative algorithm based on gradient descent with bending and it is well suited for decentralized computation. The second algorithm reduces the problem t o a series of max‐flow problems and it computes the exact optimal initial flow in O(lN14) compu‐ tations, where IN1 is the number of nodes in the network. The third algorithm is based on a search for successive bottlenecks in the network.
Triterpenes in the hexane extract of leaves of Olea europaea L.: analysis using 13C‐NMR spectroscopy
Authors: Duquesnoy Emilie , Castola Vincent , Casanova Joseph 
Published: May 2007

AbstractTwo neutral triterpenes and a triterpene acid were identified and quantified directly, in the absence of any purification steps, in a precipitate obtained during the industrial extraction of the leaves of Olea europaea L. using 13C‐NMR spectroscopy (spectrometer operating at 4.7 T equipped with a 10 mm probe). The method was optimised in order to reduce the duration of analysis with a routine NMR spectrometer. Together with long‐chain linear compounds, erythrodiol, uvaol and oleanolic acid accounted for 27.3, 18.3 and 12.5% of the precipitate, respectively. Copyright © 2007 John Wiley & Sons, Ltd.
Structure and morphology of nanocomposite films prepared from polyvinyl alcohol and silver nitrate: Influence of thermal treatment
Authors: Clémenson S. , David L. , Espuche E. 
Published: May 2007

AbstractHybrid organic/inorganic films have been prepared from an aqueous solution of polyvinyl alcohol (PVA) and silver nitrate (AgNO3). The silver nanoparticles have been generated in the PVA matrix by thermal treatments. The structure and the morphology of the hybrid films have been studied as a function of the silver precursor concentration and of the annealing conditions for a wide range of annealing temperatures. It was shown that in the uncured hybrid film most of the silver ions were initially coordinated with the polymer OH groups to form a chelate structure. A nanostructuration effect leading to the formation of crystalline silver nanoparticles was evidenced for annealing treatments performed at temperatures higher than 90 °C. For a curing temperature equal to 110 °C, the sizes of the formed nanoparticles were only slightly increasing as a function of annealing time and the effect of AgNO3 complex amount in this curing condition was also significant, but slight. Annealing at a temperature equal to 160 °C thus at a temperature for which a part of the crystalline phase of PVA was melt led to an important increase of the size of the generated metal nanoparticles. The evolution of the morphology was discussed for each curing temperature as a function of the kinetics of the nanostructuration, of the size of the matrix amorphous lamellae and of the polymer chain mobility. © 2007 Wiley Periodicals, Inc. J Polym Sci Part A: Polym Chem 45: 2657–2672, 2007
Electric properties of formaldehyde, thioformaldehyde, urea, formamide, and thioformamide—Post‐HF and DFT study
Authors: Benková Zuzana , Černušák Ivan , Zahradník Pavol 
Published: May 2007

AbstractDipole moments μ, static electric polarizabilities α, and hyperpolarizabilities β of formaldehyde, thioformaldehyde, urea, formamide, and thioformamide have been evaluated in the DFT and post‐HF approximations. Within the DFT, the family of HCTH and hybrid functionals (B3LYP, B97–1) have been adopted. The qualitative and quantitative performance of both functional types have been examined by confrontation with the CCSD(T) method. The DFT model appears to be adequate for dipole moments and polarizabilities, while the hyperpolarizabilities are exaggerated, especially βyyy (too negative) and βzzz (too positive) components. The replacement of oxygen by sulfur reduces the DFT hyperpolarizability, which contradicts an increase predicted with the post‐HF approach. HCTH dipole moments in majority of cases are in better agreement with the CCSD(T) estimates than are the hybrid functionals. On the other hand, the hybrid functionals perform slightly better for polarizability and hyperpolarizability evaluations. The effects of basis set size with aug‐cc‐pVXZ (X = D, T, Q) on the electric properties have also been studied. The sensitivity of the electric properties to the basis set effects increases from the dipole moment to the hyperpolarizability. The axial αzz and βzzz components display smaller sensitivity to the basis set extension. The carbonyl/thiocarbonyl containing molecules are characterized by negative/positive sign of hyperpolarizability vector projection into the dipole moment direction. © 2007 Wiley Periodicals, Inc. Int J Quantum Chem, 2007
Strömung an einer Luftblase im senkrechten Rohr
Authors: Dumitrescu D. T. 
Published: May 2007

AbstractDie Aufgabe: Form und Geschwindigkeit einer in einem vertikalen Rohr aufsteigenden, unendlich langen Luftblase zu finden, führt unter Vernachlässigung der Kapillar‐ und Zähigkeitskräfte auf ein Eigenwertproblem der Differentialgleichung Δφ=0, das in erster Annäherung unter der der Wirklichkeit gut entsprechenden Annahme gelöst wird, daß der Meridianschnitt der Blase in der Umgebung der Kuppe durch den Krümmungskreis ersetzt werden kann. Der Eigenwert, der sich als Funktion dieses Krümmungsradius angeben läßt, wird dadurch bestimmt, daß die asymptotische Lösung mit stetiger Tangente in den Krümmungskreis übergehen soll. Berechneter und experimentell gefundener Wert stimmen gut überein.
Risk Assessment and Genetic Counseling for Hereditary Breast and Ovarian Cancer: Recommendations of the National Society of Genetic Counselors
Authors: Berliner Janice L. , Fay Angela Musial 
Published: May 2007

AbstractThese cancer genetic counseling recommendations describe the medical, psychosocial and ethical implications of identifying at‐risk individuals for hereditary breast and ovarian cancer (HBOC) through cancer risk assessment, with or without genetic susceptibility testing. They were developed by members of the Practice Issues Subcommittee of the National Society of Genetic Counselors’ Familial Cancer Risk Counseling Special Interest Group. The information contained in this document is derived from extensive review of the current literature on cancer genetic risk assessment as well as the professional expertise of genetic counselors with significant experience in education and counseling regarding hereditary breast and ovarian cancer. Critical components of the process include the ascertainment of medical and family histories, determination and communication of cancer risk, assessment of risk perception, education regarding the genetics of HBOC, discussion of molecular testing for HBOC if appropriate (including benefits, risks and limitations) and any necessary follow‐up. These recommendations do not dictate an exclusive course of management or guarantee a specific outcome. Moreover, they do not replace the professional judgment of a health care provider based on the clinical situation of a client.
Amla (Emblica officinalisGaertn.) prevents dyslipidaemia and oxidative stress in the ageing process
Authors: Yokozawa Takako , Young Kim Hyun , Ju Kim Hyun , Okubo Tsutomu , Chu Djoing-Chi , Raj Juneja Lekh 
Published: May 2007

Amla (Emblica officinalisGaertn.) is widely used in Indian medicine for the treatment of various diseases. We have investigated the effects of amla on the lipid metabolism and protein expression involved in oxidative stress during the ageing process. SunAmla or ethyl acetate extract of amla, a polyphenol-rich fraction, was administered at a dose of 40 or 10 mg/kg body weight per d for 100 d to young rats aged 2 months and aged rats aged 10 months. The lipid levels, such as cholesterol and TAG, in serum and liver were markedly elevated in aged control rats, while they were significantly decreased by the administration of amla. The PPARα is known to regulate the transcription of genes involved in lipid and cholesterol metabolism. The PPARα protein level in liver was reduced in aged control rats. However, the oral administration of amla significantly increased the hepatic PPARα protein level. In addition, oral administration of amla significantly inhibited the serum and hepatic mitochondrial thiobarbituric acid-reactive substance levels in aged rats. Moreover, the elevated expression level of bax was significantly decreased after the oral administration of amla, while the level of bcl-2 led to a significant increase. Furthermore, the expressions of hepatic NF-κB, inducible NO synthase (iNOS), and cyclo-oxygenase-2 (COX-2) protein levels were also increased with ageing. However, amla extract reduced the iNOS and COX-2 expression levels by inhibiting NF-κB activation in aged rats. These results indicate that amla may prevent age-related hyperlipidaemia through attenuating oxidative stress in the ageing process.
Fusarium Wilt of Bitterroot (Lewisia cotyledon) in Italy Caused by Fusarium oxysporum
Authors: Garibaldi A. , Gilardi G. , Gullino M. L. 
Published: May 2007

During the spring of 2004, bitterroot (Lewisia cotyledon (S. Wats.) B.L. Robins), a flowering perennial of interest for rock gardens, showed symptoms of a wilt disease in several commercial nurseries located in Piedmont (northern Italy). Ten to thirty percent of plants from several different nurseries were affected. Wilted plants were first observed approximately 20 days after being transplanted into containers when outside temperatures ranged from 15 to 22°C. Symptomatic plants were stunted with yellowed leaves and brown-to-black veins. The vascular browning extended into the crown and was continuous with a brown discoloration in the vascular system of the crown and upper taproot. Fusarium oxysporum, identified on the basis of colony and conidia morphology (1), was consistently and readily isolated from symptomatic vascular tissue onto a Fusarium-selective medium (2). Three isolates were transferred to casein hydrolysate and grown for 10 days to produce conidial inoculum. Healthy 30-day-old plants were inoculated by dipping roots into a (1 × 106 CFU/ml) conidial suspension. Plants were then transplanted into pots filled with steam-sterilized soil. Noninoculated plants served as a control. Plants (12 per treatment) were placed in a climatic chamber at 25°C. Wilt symptoms and vascular discoloration in the roots, crown, and veins developed within 20 days on each inoculated plant, while noninoculated plants remained healthy. F. oxysporum was consistently reisolated from symptomatic plants. The pathogenicity test was conducted twice with the same result. One isolate of the pathogen has been deposited in the ATCC culture collection. To our knowledge, this is the first report of F. oxysporum on L. cotyledon in Italy and elsewhere in the world. Currently, this disease is present in several nurseries in the Piedmont Region of Italy. References: (1) C. Booth. Fusarium. CMI, Kew, UK, 1977. (2) H. Komada. Rev. Plant Prot. Res. 8:114, 1975.