bluuebunny/crossref_metadata_2025_split huggingface dataset:
What’s new in muscle and peripheral nerve diseases?
Authors: Shelton G. D. 
Published: November 2007

SummaryIt is likely that most neuromuscular diseases that are described in humans will have a counterpart in our companion animals. With the advent of molecular genetics and the completion of the canine and feline genomes, an ever expanding number of DNA-based tests should become available for the diagnosis of muscle and peripheral nerve diseases. Molecular testing procedures should enable us to continue to unravel the molecular basis of neuromuscular diseases for which the cause is still unknown. It is important that accurate clinical evaluations and diagnostic testing, including muscle and peripheral nerve biopsies, are performed in order to reach these goals. This review focuses on recently identified inherited neuromuscular diseases in companion animals.
Impact of Scale and Aggregation on the Terrestrial Water Exchange: Integrating Land Surface Models and Rhône Catchment Observations
Authors: Stöckli Reto , Vidale Pier Luigi , Boone Aaron , Schär Christoph 
Published: November 2007

Abstract
Land surface models (LSMs) used in climate modeling include detailed above-ground biophysics but usually lack a good representation of runoff. Both processes are closely linked through soil moisture. Soil moisture however has a high spatial variability that is unresolved at climate model grid scales. Physically based vertical and horizontal aggregation methods exist to account for this scaling problem. Effects of scaling and aggregation have been evaluated in this study by performing catchment-scale LSM simulations for the Rhône catchment. It is found that evapotranspiration is not sensitive to soil moisture over the Rhône but it largely controls total runoff as a residual of the terrestrial water balance. Runoff magnitude is better simulated when the vertical soil moisture fluxes are resolved at a finer vertical resolution. The use of subgrid-scale topography significantly improves both the timing of runoff on the daily time scale (response to rainfall events) and the magnitude of summer baseflow (from seasonal groundwater recharge). Explicitly accounting for soil moisture as a subgrid-scale process in LSMs allows one to better resolve the seasonal course of the terrestrial water storage and makes runoff insensitive to the used grid scale. However, scale dependency of runoff to above-ground hydrology cannot be ignored: snowmelt runoff from the Alpine part of the Rhône is sensitive to the spatial resolution of the snow scheme, and autumnal runoff from the Mediterranean part of the Rhône is sensitive to the spatial resolution of precipitation.
Convective Planetary Boundary Layer Interactions with the Land Surface at Diurnal Time Scales: Diagnostics and Feedbacks
Authors: Santanello Joseph A. , Friedl Mark A. , Ek Michael B. 
Published: November 2007

Abstract
The convective planetary boundary layer (PBL) integrates surface fluxes and conditions over regional and diurnal scales. As a result, the structure and evolution of the PBL contains information directly related to land surface states. To examine the nature and magnitude of land–atmosphere coupling and the interactions and feedbacks controlling PBL development, the authors used a large sample of radiosonde observations collected at the southern Atmospheric Research Measurement Program–Great Plains Cloud and Radiation Testbed (ARM-CART) site in association with simulations of mixed-layer growth from a single-column PBL/land surface model. The model accurately predicts PBL evolution and realistically simulates thermodynamics associated with two key controls on PBL growth: atmospheric stability and soil moisture. The information content of these variables and their influence on PBL height and screen-level temperature can be characterized using statistical methods to describe PBL–land surface coupling over a wide range of conditions. Results also show that the first-order effects of land–atmosphere coupling are manifested in the control of soil moisture and stability on atmospheric demand for evapotranspiration and on the surface energy balance. Two principal land–atmosphere feedback regimes observed during soil moisture drydown periods are identified that complicate direct relationships between PBL and land surface properties, and, as a result, limit the accuracy of uncoupled land surface and traditional PBL growth models. In particular, treatments for entrainment and the role of the residual mixed layer are critical to quantifying diurnal land–atmosphere interactions.
An Alternative Mass Flux Profile in the Kain–Fritsch Convective Parameterization and Its Effects in Seasonal Precipitation
Authors: Anderson Christopher J. , Arritt Raymond W. , Kain John S. 
Published: November 2007

Abstract
The authors have altered the vertical profile of updraft mass flux detrainment in an implementation of the Kain–Fritsch2 (KF2) convective parameterization within the fifth-generation Pennsylvania State University–National Center for Atmospheric Research (Penn State–NCAR) Mesoscale Model (MM5). The effect of this modification was to alter the vertical profile of convective parameterization cloud mass (including cloud water and ice) supplied to the host model for explicit simulation by the grid-resolved dynamical equations and parameterized microphysical processes. These modifications and their sensitivity to horizontal resolution in a matrix of experimental simulations of the June–July 1993 flood in the central United States were tested.
The KF2 modifications impacted the diurnal cycle of precipitation by reducing precipitation from the convective parameterization and increasing precipitation from more slowly evolving mesoscale processes. The modified KF2 reduced an afternoon bias of high precipitation rate in both low- and high-resolution simulations but affected mesoscale precipitation processes only in high-resolution simulations. The combination of high-resolution and modified KF2 resulted in more frequent and more realistically clustered propagating, nocturnal mesoscale precipitation events and agreed best with observations of the nocturnal precipitation rate.
Evaluation of the Hydrological Cycle over the Mississippi River Basin as Simulated by the Canadian Regional Climate Model (CRCM)
Authors: Music Biljana , Caya Daniel 
Published: November 2007

AbstractThe water cycle over a given region is governed by many complex multiscale interactions and feedbacks, and their representation in climate models can vary in complexity. To understand which of the key processes require better representation, evaluation and validation of all components of the simulated water cycle are required. Adequate assessing of the simulated hydrological cycle over a given region is not trivial because observations for various water cycle components are seldom available at the regional scale.In this paper, a comprehensive validation method of the water budget components over a river basin is presented. In addition, the sensitivity of the hydrological cycle in the Canadian Regional Climate Model (CRCM) to a more realistic representation of the land surface processes, as well as radiation, cloud cover, and atmospheric boundary layer mixing is investigated. The changes to the physical parameterizations are assessed by evaluating the CRCM hydrological cycle over the Mississippi River basin. The first part of the evaluation looks at the basin annual means. The second part consists of the analysis and validation of the annual cycle of all water budget components. Finally, the third part is directed toward the spatial distribution of the annual mean precipitation, evapotranspiration, and runoff.Results indicate a strong response of the CRCM evapotranspiration and precipitation biases to the physical parameterization changes. Noticeable improvement was obtained in the simulated annual cycles of precipitation, evapotranspiration, moisture flux convergence, and terrestrial water storage tendency when more sophisticated physical parameterizations were used. Some improvements are also observed for the simulated spatial distribution of precipitation and evapotranspiration. The simulated runoff is less sensitive to changes in the CRCM physical parameterizations.
Systematic Bias in Land Surface Models
Authors: Abramowitz Gab , Pitman Andy , Gupta Hoshin , Kowalczyk Eva , Wang Yingping 
Published: November 2007

Abstract
A neural network–based flux correction technique is applied to three land surface models. It is then used to show that the nature of systematic model error in simulations of latent heat, sensible heat, and the net ecosystem exchange of CO2 is shared between different vegetation types and indeed different models. By manipulating the relationship between the dataset used to train the correction technique and that used to test it, it is shown that as much as 45% of per-time-step model root-mean-square error in these flux outputs is due to systematic problems in those model processes insensitive to changes in vegetation parameters. This is shown in the three land surface models using flux tower measurements from 13 sites spanning 2 vegetation types. These results suggest that efforts to improve the representation of fundamental processes in land surface models, rather than parameter optimization, are the key to the development of land surface model ability.
The Impact of Different Physical Parameterizations and Their Interactions on Cold Season QPF in the American River Basin
Authors: Jankov Isidora , Schultz Paul J. , Anderson Christopher J. , Koch Steven E. 
Published: November 2007

Abstract
The most significant precipitation events in California occur during the winter and are often related to synoptic-scale storms from the Pacific Ocean. Because of the terrain characteristics and the fact that the urban and infrastructural expansion is concentrated in lower elevation areas of the California Central Valley, a high risk of flooding is usually associated with these events. In the present study, the area of interest was the American River basin (ARB). The main focus of the present study was to investigate methods for Quantitative Precipitation Forecast (QPF) improvement by estimating the impact that various microphysical schemes, planetary boundary layer (PBL) schemes, and initialization methods have on cold season precipitation, primarily orographically induced. For this purpose, 3-km grid spacing Weather Research and Forecasting (WRF) model simulations of four Hydrometeorological Test bed (HMT) events were used. For each event, four different microphysical schemes and two different PBL schemes were used. All runs were initialized with both a diabatic Local Analysis and Prediction System (LAPS) “hot” start and 40-km eta analyses.
To quantify the impact of physical schemes, their interactions, and initial conditions upon simulated rain volume, the factor separation methodology was used. The results showed that simulated rain volume was particularly affected by changes in microphysical schemes for both initializations. When the initialization was changed from the LAPS to the eta analysis, the change in the PBL scheme and corresponding synergistic terms (which corresponded to the interactions between different microphysical and PBL schemes) resulted in a statistically significant impact on rain volume. In addition, by combining model runs based on the knowledge about their impact on simulated rain volume obtained through the factor separation methodology, the bias in simulated rain volume was reduced.
El Niño Effects and Upwelling off South Australia
Authors: Middleton John F. , Arthur Craig , Van Ruth Paul , Ward Tim M. , McClean Julie L. , Maltrud Mathew E. , Gill Peter , Levings Andrew , Middleton Sue 
Published: November 2007

Abstract
To determine the possible importance of ENSO events along the coast of South Australia, an exploratory analysis is made of meteorological and oceanographic data and output from a global ocean model. Long time series of coastal sea level and wind stress are used to show that while upwelling favorable winds have been more persistent since 1982, ENSO events (i) are largely driven by signals from the west Pacific Ocean shelf/slope waveguide and not local meteorological conditions, (ii) can account for 10-cm changes in sea level, and (iii) together with wind stress, explain 62% of the variance of annual-averaged sea level. Thus, both local winds and remote forcing from the west Pacific are likely important to the low-frequency shelf edge circulation. Evidence also suggests that, since 1983, wintertime downwelling during the onset of an El Niño is reduced and the following summertime upwelling is enhanced. In situ data show that during the 1998 and 2003 El Niño events anomalously cold (10.5°–11.5°C) water is found at depths of 60–120 m and is more than two standard deviations cooler than the mean. A regression showed that averaged sea level can provide a statistically significant proxy for these subsurface temperature changes and indicates a 2.2°C decrease in temperature for the 10-cm decrease in sea level that was driven by the 1998 El Niño event. Limited current- meter observations, long sea level records, and output from a global ocean model were also examined and provide support for the hypothesis that El Niño events substantially reduce wintertime (but not summertime) shelf-edge currents. Further research to confirm this asymmetric response and its cause is required.
The Western North Atlantic Shelfbreak Current System in Summer
Authors: Fratantoni Paula S. , Pickart Robert S. 
Published: November 2007

Abstract
Twelve years of historical hydrographic data, spanning the period 1990–2001, are analyzed to examine the along-stream evolution of the western North Atlantic Ocean shelfbreak front and current, following its path between the west coast of Greenland and the Middle Atlantic Bight. Over 700 synoptic sections are used to construct a mean three-dimensional description of the summer shelfbreak front and to quantify the along-stream evolution in properties, including frontal strength and grounding position. Results show that there are actually two fronts in the northern part of the domain—a shallow front located near the shelf break and a deeper front centered in the core of Irminger Water over the upper slope. The properties of the deeper Irminger front erode gradually to the south, and the front disappears entirely near the Grand Banks of Newfoundland. The shallow shelfbreak front is identifiable throughout the domain, and its properties exhibit large variations from north to south, with the largest changes occurring near the Tail of the Grand Banks. Despite these structural changes, and large variations in topography, the foot of the shelfbreak front remains within 20 km of the shelf break. The hydrographic sections are also used to examine the evolution of the baroclinic velocity field and its associated volume transport. The baroclinic velocity structure consists of a single velocity core that is stronger and penetrates deeper where the Irminger front is present. The baroclinic volume transport decreases by equal amounts at the southern end of the Labrador Shelf and at the Tail of the Grand Banks. Overall, the results suggest that the Grand Banks is a geographically critical location in the North Atlantic shelfbreak system.
Role of Eddies in Chlorofluorocarbon Transport in Wind-Driven Oceanic Layers
Authors: Ishida Akio , Sasai Yoshikazu , Yamanaka Yasuhiro 
Published: November 2007

Abstract
In this study the global distribution and transport of chlorofluorocarbons (CFCs) in the oceans are investigated using a high-resolution numerical model. The authors focus on the effects of wind-driven processes such as subduction and ventilation on the distribution of CFC-11 within surface and thermocline layers. Local maxima of tracer inventory are identified in oceanic regions. Two major absorption regions in the South Pacific Ocean are located west of South America and northeast of New Zealand in boundary latitudes between subtropical and subantarctic areas. In the North Pacific and south Indian Oceans, the positions of the local maxima of tracers migrate west–east with increasing density. The relationship between water formation and tracer distribution is discussed by comparing the wintertime mixed layer depth and mean circulation. The contributions of mean and eddy transport of the meridional overturning cells to tracer transport are analyzed. Stationary eddies have a large impact in the Southern Ocean, while transient eddies are crucial for the compensation of mean transport in the equatorial oceans. Mean and seasonal variability components of meridional tracer transport are dominant in the subtropics; however, eddy transport also plays a significant role.
The Intermediate Water Depth Limit of the Zakharov Equation and Consequences for Wave Prediction
Authors: Janssen Peter A. E. M. , Onorato Miguel 
Published: November 2007

Abstract
Finite-amplitude deep-water waves are subject to modulational instability, which eventually can lead to the formation of extreme waves. In shallow water, finite-amplitude surface gravity waves generate a current and deviations from the mean surface elevation. This stabilizes the modulational instability, and as a consequence the process of nonlinear focusing ceases to exist when kh &lt; 1.363. This is a well-known property of surface gravity waves. Here it is shown for the first time that the usual starting point, namely the Zakharov equation, for deriving the nonlinear source term in the energy balance equation in wave forecasting models, shares this property as well. Consequences for wave prediction are pointed out.
Interventions for adult family carers of people who have had a stroke: a systematic review
Authors: Brereton Louise , Carroll Christopher , Barnston Sue 
Published: November 2007

Objective: A systematic review of the effectiveness of interventions for adult family carers of people with stroke, and an exploratory examination of the relationship between the conceptual basis of these interventions and their effectiveness. Data sources: Seventeen electronic databases and grey literature sources were searched, including ASSIA, BNI, Cochrane Library, CINAHL, EMBASE, MEDLINE, PsycINFO, Social Science Citation Index and the Science Citation Index, HMIC and the National Research Register. Authors of unpublished material were contacted for data and additional publications. Reference and citation tracking was performed on included publications. Review methods: Inclusion criteria: randomized controlled trials of interventions aimed primarily at adult family carers of people post stroke; carers were the primary sample; primary outcomes reported were for carers. Two independent reviewers screened titles and abstracts to identify publications and extract data. Quality assessment was performed to weight study findings. Results: Eight papers were found reporting on six complex, generally heterogeneous, interventions: caregiver training; education and counselling; social problem-solving partnerships, delivered principally by telephone; a psycho-educational telephone support group; a nurse-led support and education programme; and a support programme, delivered either to groups in hospital or individuals during home visits. Half of the interventions were based on stress-coping theories; the remainder did not identify a conceptual basis for the intervention. Conclusions: Some benefits were reported for all interventions, although trials were generally of low quality, preventing firm conclusions being drawn. The presence of a conceptual basis for interventions does not appear to influence effectiveness.
Six hours in the laboratory: a quantification of practice time during constraint-induced therapy (CIT)
Authors: Kaplon Richard T. , Prettyman Michelle G. , Kushi Cynthia L. , Winstein Carolee J. 
Published: November 2007

Objective: To quantify supervised in-laboratory time and practice intensity during the signature protocol specified as 6 hours/day over 10 days for the EXtremity Constraint-Induced Therapy Evaluation (EXCITE) randomized clinical trial. Design: Retrospective analysis of constraint-induced movement therapy training documentation acquired at the University of Southern California site from EXCITE (n = 38). Training documentation was reviewed and analysed to determine average and between-subject variability of supervised in-laboratory time and actual task-specific practice time for concurrence with the specified constraint-induced movement therapy protocol. Setting: Motor Behavior and Neurorehabilitation Laboratory, Division of Biokinesiology and Physical Therapy, University of Southern California, Los Angeles, CA, USA. Subjects: Data from 38 participants (35 met inclusion criteria) who, upon enrolment in the EXCITE trial, were between 3 and 10 months post stroke and between 47 and 81 years of age. Results: The training records revealed an average of 64 hours (SD = 2.6) supervised in-laboratory time for 35 participants across 10 days of training. More importantly, the average time on task-specific practice was 3.95 hours per day (SD = 5.7) representing 62% of the in-laboratory time. Supervised in-laboratory time for 10 training days was consistent across the sample as was total practice time for days 2—10, with a substantially lower practice time on the initial training day. Conclusions: Participants tolerated an intense task-specific practice schedule that consisted of approximately two-thirds of the specified minimum 6 hour in-laboratory time and was distributed evenly between adaptive task practice (shaping) and task practice components.
Exercise capacity, physical activity patterns and outcomes six years after cardiac rehabilitation in patients with heart failure
Authors: Mueller Lionel , Myers Jonathan , Kottman Wilhard , Oswald Ulrike , Boesch Claudia , Arbrol Nayana , Dubach Paul 
Published: November 2007

Objective: To determine the short- and long-term effects of an intensive, concentrated rehabilitation programme in patients with chronic heart failure. Design: Randomized controlled trial, with one-month and six-year evaluations. Setting: Residential rehabilitation centre in Switzerland. Subjects: Fifty patients with chronic heart failure, randomized to exercise or control groups. Interventions: A rehabilitation programme lasting one month, including educational sessions, a low-fat diet, and 2 hours of individually prescribed exercise daily. Main measures: Exercise test responses, health outcomes and physical activity patterns. Results: Peak Vo2 increased 21.4% in the exercise group during the rehabilitation programme (P<0.05), whereas peak Vo2 did not change among controls. After the six-year follow-up period, peak Vo2 was only slightly higher than that at baseline in the trained group (7%, NS), while peak Vo2 among controls was unchanged. During long-term follow-up, 9 and 12 patients died in the exercise and control groups, respectively (P = 0.63). At six years, physical activity patterns tended to be higher in the exercise group; the mean energy expenditure values over the last year were 2704 ± 1970 and 2085 ± 1522 kcal/week during recreational activities for the exercise and control groups, respectively. However, both groups were more active compared to energy expenditure prior to their cardiac event (P<0.001). Conclusions: Six years after participation in a residential rehabilitation programme, patients with chronic heart failure had slightly better outcomes than control subjects, maintained exercise capacity and engaged in activities that exceed the minimal amount recommended by guidelines for cardiovascular health.