bluuebunny/crossref_metadata_2025_split huggingface dataset:
How does Human Resource Management help service organizations to thrive in uncertainties and risks: Postcrisis as a context
Authors: Chen Yang , Fu Rong , Xie Mengying , Cooke Fang Lee , Song Qi 
Published: March 2024

AbstractWith heightened uncertainties and risks in the fluctuating business environment, existing studies have concentrated on elucidating how service organizations leverage human resource practices to adapt to and survive such unforeseen and disruptive threats. However, how such practices could serve the strategic objective of cultivating a sustainably thriving workforce across different situations is not well understood. Thriving is a core transitional state that fosters positive behaviors, such as creative customer‐related problem‐solving. Applying social information processing theory, we propose and test a model by exploring how organizations that engage in thriving‐oriented human resource management (HRM) encourage employees to take responsibility and promote constructive change, thereby activating their creative problem‐solving behaviors. Specifically, we theorize and develop measures to promote thriving‐oriented HRM in Study 1. In Study 2, we collected multisource and multi‐wave data from 296 frontline service employees and 45 supervisors in China. Our findings reveal that thriving‐oriented HRM is positively related to felt responsibility for change, which ultimately encourages creative problem‐solving. We also show that the threat imposed by a crisis, that is, the COVID‐19 pandemic, strengthens the positive relationship between thriving‐oriented HRM and felt responsibility for change. Our study contributes to the HRM literature, especially on thriving‐oriented HRM and employee perception, and has practical implications for service organizations in the uncertain context.
Lactobacillus rhamnosus GG triggers intestinal epithelium injury in zebrafish revealing host dependent beneficial effects
Authors: Zhang Zhen , Zhang Hong‐Ling , Yang Da‐Hai , Hao Qiang , Yang Hong‐Wei , Meng De‐Long , Meindert de Vos Willem , Guan Le‐Luo , Liu Shu‐Bin , Teame Tsegay , Gao Chen‐Chen , Ran Chao , Yang Ya‐Lin , Yao Yuan‐Yuan , Ding Qian‐Wen , Zhou Zhi‐Gang 
Published: March 2024

AbstractLactobacillus rhamnosus GG (LGG), the well‐characterized human‐derived probiotic strain, possesses excellent properties in the maintenance of intestinal homeostasis, immunoregulation and defense against gastrointestinal pathogens in mammals. Here, we demonstrate that the SpaC pilin of LGG causes intestinal epithelium injury by inducing cell pyroptosis and gut microbial dysbiosis in zebrafish. Dietary SpaC activates Caspase‐3−GSDMEa pathways in the intestinal epithelium, promotes intestinal pyroptosis and increases lipopolysaccharide (LPS)‐producing gut microbes in zebrafish. The increased LPS subsequently activates Gaspy2−GSDMEb pyroptosis pathway. Further analysis reveals the Caspase‐3−GSDMEa pyroptosis is initiated by the species‐specific recognition of SpaC by TLR4ba, which accounts for the species‐specificity of the SpaC‐inducing intestinal pyroptosis in zebrafish. The observed pyroptosis‐driven gut injury and microbial dysbiosis by LGG in zebrafish suggest that host‐specific beneficial/harmful mechanisms are critical safety issues when applying probiotics derived from other host species and need more attention.
Arbuscular mycorrhizal fungal interactions bridge the support of root‐associated microbiota for slope multifunctionality in an erosion‐prone ecosystem
Authors: Qiu Tianyi , Peñuelas Josep , Chen Yinglong , Sardans Jordi , Yu Jialuo , Xu Zhiyuan , Cui Qingliang , Liu Ji , Cui Yongxing , Zhao Shuling , Chen Jing , Wang Yunqiang , Fang Linchuan 
Published: March 2024

AbstractThe role of diverse soil microbiota in restoring erosion‐induced degraded lands is well recognized. Yet, the facilitative interactions among symbiotic arbuscular mycorrhizal (AM) fungi, rhizobia, and heterotrophic bacteria, which underpin multiple functions in eroded ecosystems, remain unclear. Here, we utilized quantitative microbiota profiling and ecological network analyses to explore the interplay between the diversity and biotic associations of root‐associated microbiota and multifunctionality across an eroded slope of a Robinia pseudoacacia plantation on the Loess Plateau. We found explicit variations in slope multifunctionality across different slope positions, associated with shifts in limiting resources, including soil phosphorus (P) and moisture. To cope with P limitation, AM fungi were recruited by R. pseudoacacia, assuming pivotal roles as keystones and connectors within cross‐kingdom networks. Furthermore, AM fungi facilitated the assembly and composition of bacterial and rhizobial communities, collectively driving slope multifunctionality. The symbiotic association among R. pseudoacacia, AM fungi, and rhizobia promoted slope multifunctionality through enhanced decomposition of recalcitrant compounds, improved P mineralization potential, and optimized microbial metabolism. Overall, our findings highlight the crucial role of AM fungal‐centered microbiota associated with R. pseudoacacia in functional delivery within eroded landscapes, providing valuable insights for the sustainable restoration of degraded ecosystems in erosion‐prone regions.
Near‐infrared emitting metal halide materials: Luminescence design and applications
Authors: Liu Dongjie , Dang Peipei , Zhang Guodong , Lian Hongzhou , Li Guogang , Lin Jun 
Published: March 2024

AbstractNear‐infrared (NIR) luminescent metal halide (LMH) materials have attracted great attention in various optoelectronic applications due to their low‐temperature solution‐processable synthesis, abundant crystallographic/electronic structures, and unique optoelectronic properties. However, some challenges still remain in their luminescence design, performance improvement, and application assignments. This review systematically summarizes the development of NIR LMHs through classifying NIR luminescent origins into four major categories: band‐edge emission, self‐trapped exciton (STE) emission, ion emission, and defect‐related emission. The luminescence mechanisms of different types of NIR LMHs are discussed in detail by analyzing typical examples. Reasonable strategies for designing and optimizing luminescence/optoelectronic properties of NIR LMHs are summarized, including bandgap engineering, self‐trapping state engineering, chemical composition modification, energy transfer, and other auxiliary strategies such as improvement of synthesis scheme and post‐processing. Furthermore, application prospects based on the optoelectronic devices are revealed, including phosphor‐converted light‐emitting diodes (LEDs), electroluminescent LEDs, photodetectors, solar cells, and x‐ray scintillators, as well as demonstrations of some related practical applications. Finally, the existing challenges and future perspectives on the development of NIR LMH materials are critically proposed. This review aims to provide general understanding and guidance for the design of high‐performance NIR LMHs materials.image
Processes of Creating a National Cancer Registry System in the Philippines
Authors: Tan Abigail Lim , Feliciano Erin Jay G. , Habaluyas Katrina Erika Rocha , Bolong Nina Patricia , Wong John Q. 
Published: March 2024

AbstractAs a new entrant in the Philippine Cancer Health Information Network, the Philippine Cancer Center (PCC) was pushed to establish the National Cancer Registry as mandated by the National Integrated Cancer Control Act (NICCA). The researchers used a rapid review and rapid realist review approaches which made use of evidence from literature and data from 43 key informant interviews and FGDs to create the National Cancer Registry Development Plan. The results were summarized using a cancer data process flow diagram, context‐view system architecture model, and logic models detailing the roadmap plans for the next 10 years. The study was able to show how the development of a national cancer registry plan that seeks to unite existing population‐based cancer registries (PBCRs) and hospital‐based cancer registries (HBCRs) is only possible through extensive collaboration and effective stakeholder engagement. Using an evidence‐based approach with expert knowledge and validation, the Philippine National Cancer Registry Development Plan was created, an example of an e‐health policy making process from which other developing countries can learn from.
Ultrasound‐based radiomics‐clinical nomogram for noninvasive prediction of residual cancer burden grading in breast cancer
Authors: Li Zhi‐Yong , Wu Sheng‐Nan , Lin Zhen‐Hu , Jiang Mei‐Chen , Chen Cong , Liang Rong‐Xi , Lin Wen‐Jin , Xue En‐Sheng 
Published: March 2024

AbstractPurposeTo assess the predictive value of an ultrasound‐based radiomics‐clinical nomogram for grading residual cancer burden (RCB) in breast cancer patients.MethodsThis retrospective study of breast cancer patients who underwent neoadjuvant therapy (NAC) and ultrasound scanning between November 2020 and July 2023. First, a radiomics model was established based on ultrasound images. Subsequently, multivariate LR (logistic regression) analysis incorporating both radiomic scores and clinical factors was performed to construct a nomogram. Finally, Receiver operating characteristics (ROC) curve analysis and decision curve analysis (DCA) were employed to evaluate and validate the diagnostic accuracy and effectiveness of the nomogram.ResultsA total of 1122 patients were included in this study. Among them, 427 patients exhibited a favorable response to NAC chemotherapy, while 695 patients demonstrated a poor response to NAC therapy. The radiomics model achieved an AUC value of 0.84 in the training cohort and 0.83 in the validation cohort. The ultrasound‐based radiomics‐clinical nomogram achieved an AUC value of 0.90 in the training cohort and 0.91 in the validation cohort.ConclusionsUltrasound‐based radiomics‐clinical nomogram can accurately predict the effectiveness of NAC therapy by predicting RCB grading in breast cancer patients.
Association between the health vulnerability of family members and concern about the contagion of COVID‐19 in Peruvian residents after the pandemic
Authors: Olavarria Coronado Richard D. , Aranda Medina Julianna , Chávez Sosa Janett V. , Huancahuire‐Vega Salomón 
Published: March 2024

AbstractBackgroundThe COVID‐19 pandemic has created additional challenges for family health. Worry, fear, and anxiety associated with this disease can affect the perception of family health. The study's objective was to analyze the factors associated with health vulnerability of family members in the Peruvian population after pandemic.MethodsObservational, cross‐sectional, and analytical study. Sampling was nonprobabilistic. The sample consisted of 519 residents who met the following inclusion criteria: Peruvian resident, of both genders, over 18 years of age, who lives with their family, and who agrees to participate in the study. For data collection, the “SALUFAM” and “PRE‐COVID‐19” scales were used, which measure the health vulnerability of family members and concern about the contagion of COVID‐19, respectively. Data collection was done between January and March, 2023.ResultsLiving in the Coast region increases by 3.299 times (95% CI = 1.55–9.28; p = 0.003) the probability of lower family health vulnerability compared to residents from the Jungle region. In the same way, having a low concern about the contagion of COVID‐19 increases 2.77 times (95% CI = 1.02–7.53; p = 0.044) the probability of less vulnerability to family health, unlike participants who are highly concerned about the contagion of COVID‐19.ConclusionsIt should be necessary to design prevention and family health promotion strategies according to the geographical region; it is also essential to provide education on the risks and the importance of prevention measures for COVID‐19, regardless of their initial level of concern.
Photocatalytic synthesis of 2,4‐substituted quinazolines via a one‐pot, three‐component reaction under catalyst‐free conditions
Authors: Xie Zongbo , Chen Xuehua , Jiang Guofang , Fan Qianwen , Yang Hong , Le Zhanggao 
Published: March 2024

AbstractA novel, catalyst‐free photoinduced synthesis of 2,4‐substituted quinazoline using 2‐amino‐aryl ketone, an aldehyde, and ammonium acetate was developed. A series of 2,4‐substituted quinazoline compounds were obtained via irradiating the reactants with a light‐emitting diode light (18 W) at room temperature. The broad substrate range and excellent gram‐scale experimental results demonstrate the versatility of the reaction. To the best of our knowledge, the synthesis of 2,4‐substituted quinazoline using ammonium acetate as the nitrogen source under photocatalysis has not been reported thus far. This method utilizes visible light oxidation to eliminate the use of oxidants in the reaction and is complementary to previous methods.
Characteristics differentiating problem representation synthesis between novices and experts
Authors: McQuade Casey N. , Simonson Michael G. , Lister Julia , Olson Andrew P. J. , Zwaan Laura , Rothenberger Scott D. , Bonifacino Eliana 
Published: March 2024

AbstractBackgroundFormulating a thoughtful problem representation (PR) is fundamental to sound clinical reasoning and an essential component of medical education. Aside from basic structural recommendations, little consensus exists on what characterizes high‐quality PRs.ObjectivesTo elucidate characteristics that distinguish PRs created by experts and novices.MethodsEarly internal medicine residents (novices) and inpatient teaching faculty (experts) from two academic medical centers were given two written clinical vignettes and were instructed to write a PR and three‐item differential diagnosis for each. Deductive content analysis described the characteristics comprising PRs. An initial codebook of characteristics was refined iteratively. The primary outcome was differences in characteristic frequencies between groups. The secondary outcome was characteristics correlating with diagnostic accuracy. Mixed‐effects regression with random effects modeling compared case‐level outcomes by group.ResultsOverall, 167 PRs were analyzed from 30 novices and 54 experts. Experts included 0.8 fewer comorbidities (p < .01) and 0.6 more examination findings (p = .01) than novices on average. Experts were less likely to include irrelevant comorbidities (odds ratio [OR] = 0.4, 95% confidence interval [CI] = 0.2–0.8) or a diagnosis (OR = 0.3, 95% CI = 0.1–0.8) compared with novices. Experts encapsulated clinical data into higher‐order terms (e.g., sepsis) than novices (p < .01) while including similar numbers of semantic qualifiers (SQs). Regardless of expertise level, PRs following a three‐part structure (e.g., demographics, temporal course, and clinical syndrome) and including temporal SQs were associated with diagnostic accuracy (p < .01).ConclusionsCompared with novices, expert PRs include less irrelevant data and synthesize information into higher‐order concepts. Future studies should determine whether targeted educational interventions for PRs improve diagnostic accuracy.
Hesperetin blocks poxvirus replication with a low tendency to select for drug‐resistant viral variants
Authors: Verma Assim , Dedar Ramesh Kumar , Kumar Ram , Chander Yogesh , Kamboj Himanshu , Kumar Garvit , Verma Rekha , Kumari Santosh , Sharma Shalini , Tripathi Bhupendra N. , Barua Sanjay , Kumar Naveen 
Published: March 2024

AbstractIn this study, we demonstrated the antiviral efficacy of hesperetin against multiple poxviruses, including buffalopox virus (BPXV), vaccinia virus (VACV), and lumpy skin disease virus (LSDV). The time‐of‐addition and virus step‐specific assays indicated that hesperetin reduces the levels of viral DNA, mRNA, and proteins in the target cells. Further, by immunoprecipitation (IP) of the viral RNA from BPXV‐infected Vero cells and a cell‐free RNA‐IP assay, we demonstrated that hesperetin‐induced reduction in BPXV protein synthesis is also consistent with diminished interaction between eukaryotic translation initiation factor eIF4E and the 5′ cap of viral mRNA. Molecular docking and MD simulation studies were also consistent with the binding of hesperetin to the cap‐binding pocket of eIF4E, adopting a conformation similar to m7GTP binding. Furthermore, in a BPXV egg infection model, hesperetin was shown to suppress the development of pock lesions on the chorioallantoic membrane and associated mortality in the chicken embryos. Most importantly, long‐term culture of BPXV in the presence of hesperetin did not induce the generation of drug‐resistant viral mutants. In conclusion, we, for the first time, demonstrated the antiviral activity of hesperetin against multiple poxviruses, besides providing some insights into its potential mechanisms of action.
Impact of sex and age on the lateralisation of the tibial tubercle in normal paediatric and adolescent populations
Authors: Chen Jiebo , Sha Lin , Zhang Xueying , Bao Lei , Li Hai , Zhao Jinzhong , Xie Guoming 
Published: March 2024

AbstractPurposeNumerous methods have been proposed to characterise tubercle lateralisation. However, their normal values and related changes remain unclear. Accordingly, it was aimed to determine the potential sex and age effects and determined the optimal individualised method of diagnosing lateralisation of the tibial tubercle in patients with recurrent patellar dislocation (RPD).MethodsMeasurements included the tibial tubercle–trochlear groove (TT‐TG) distance, tibial tubercle‐posterior cruciate ligament (TT‐PCL) distance and tibial tubercle lateralisation (TTL); and the proximal tibial width (PTW), trochlear width (TW) and trochlear dysplasia index (TDI), for adjustment. A two‐way analysis of variance was used to determine the effect of age, sex and their interaction within the normal group. When the age effect was statistically significant, a nonlinear regression was created. Areas under the receiver‐operating characteristic curve (AUCs) were calculated to assess diagnostic accuracy.ResultsA total of 277 normal participants (mean [SD] age, 13.5 [2.6] years; 125 [45.1%] female) and 227 patients with RPD (mean [SD] age, 13.5 [2.6] years; 161 [58.1%] female) were analysed. It was found that in the normal group, in patients aged 7–10, TT‐PCL distance (p = 0.006), TTL (p = 0.007) and TT‐PCL/PTW (p < 0.001) were significantly larger in females than in males. A significant sex effect was also detected on TT‐TG/TW (p = 0.014). TT‐TG distance, TT‐PCL distance, TTL and TT‐PCL/PTW (in male patients) approached an established normal adult value of 12.3 mm, 20.9 mm, 0.64 and 0.28, respectively, with increasing age (p < 0.001). The AUC was greater for TT‐TG/TDI and TT‐TG/TW (p ≤ 0.01) and TT‐TG/TDI outperformed TT‐TG/TW in patients aged 15–18 (p = 0.004).ConclusionsTubercle lateralisation increased with age and was affected by sex, with the exception of TT‐TG distance and TT‐TG/TDI. TT‐TG/TDI is the optimal method of diagnosing a lateralized tibial tubercle in patients with RPD. These findings assist with the evaluation of tubercle lateralisation in that they provide a proper protocol for paediatric and adolescent populations with RPD; and thus, will help determine whether medial tubercle transfer should be included among the tailored surgical procedures considered for the treatment of patients with RPD.Level of EvidenceLevel III.
Inferior patellar mobility before and after knee arthroplasty: A comparison with healthy knees
Authors: Lachowski Krzysztof , Prill Robert , Salzmann Mikhail , Becker Roland 
Published: March 2024

AbstractPurposeThe aim of this study was to evaluate patellar mobility in patients before and after knee arthroplasty (KA) and compare it with that of healthy subjects. It was hypothesised that patellar mobility is diminished in patients with osteoarthritis (OA) and remains unchanged after KA.MethodsA total of 101 patients (59 females and 42 males) with a mean age of 70.9 ± 9.9 years underwent KA and were compared with 25 healthy individuals (seven females and 18 males) with a mean age of 32.3 ± 9.3 years. Mediolateral patellar displacement was measured by applying a force of 10 N, and the medial and lateral patellar shifts were recorded separately using a validated novel patellostabilometer. Patients were examined preoperatively and at 3 months postoperatively, assessing the range of knee motion and the clinical and functional status based on the Oxford Knee Score (OKS), Kujala Score, subjective Knee Society Score (sKSS), Forgotten Joint Score (FJS) and Western Ontario and McMaster Universities Arthritis Index (WOMAC).ResultsTotal patellar displacement was 42.1 ± 6 mm for healthy subjects, 31 ± 6 mm before surgery and 32.8 ± 7.8 mm after surgery in osteoarthritic patients (p < 0.01). The mean lateral patellar shift differed significantly between healthy individuals (17.9 ± 4 mm) and osteoarthritic patients (15.1 ± 6 mm) (p < 0.01). The mean medial patellar mobility of healthy individuals (24.2 ± 7 mm) was significantly greater than that of osteoarthritic patients (15.8 ± 4.8 mm) (p < 0.01). All scores improved significantly postoperatively. No correlation was found between patellar mobility and OKS, Kujala Score, sKSS, FJS and WOMAC (r = −0.11). Improvement in patellar mobility also showed no correlation with clinical outcomes according to OKS, Kujala Score, sKSS, FJS and WOMAC (r = 0.08).ConclusionThis study has demonstrated reduced patellar mobility in patients with OA. While patellar mobility significantly improved after KA, it may not hold clinical significance (p = 0.04). No impact on clinical outcome can be expected when the presurgical patella mobility is preserved in KA.Level of EvidenceLevel IV.
Tibial spine volume is smaller in ACL‐injured athletes compared to healthy athletes
Authors: Yahagi Yoshiyuki , Gale Tom , Nukuto Koji , Irrgang James , Musahl Volker , Anderst William 
Published: March 2024

AbstractPurposeThe aim of this study was to investigate whether the whole tibial spine volume and femoral intercondylar notch volume are risk factors for anterior cruciate ligament (ACL) injury. The hypothesis was that the whole tibial spine volume and femoral notch volume would be smaller in athletes who sustained ACL injury than in athletes with no history of ACL injury.MethodsComputed tomography scans of both knees were acquired and three‐dimensional bone models were created using Mimics to measure whole tibial spine volume and femoral notch volume. Tibial spine volume, femoral notch volume and each of these volumes normalised by tibial plateau area were compared between the ACL‐injured and the ACL‐intact group.ResultsFifty‐one athletes undergoing unilateral anatomical ACL reconstruction (17 female, 34 male: average age 22.0 ± 7.5) and 19 healthy collegiate athletes with no previous knee injury (eight female, 11 male: average age 20.1 ± 1.3) were included in this study. The whole tibial spine volume in the ACL‐injured group (2.1 ± 0.5 cm3) was 20.7% smaller than in the ACL‐intact group (2.7 ± 0.7 cm3) (p = 0.005). No differences were observed between the femoral notch volume in the ACL‐injured group (9.5 ± 2.1 cm3) and the ACL‐intact group (8.7 ± 2.7 cm3) (n.s.).ConclusionsThe main finding of this study was that the whole tibial spine volume of the ACL‐injured group was smaller than the ACL‐intact group. A small tibial spine volume can be added to the list of anatomical risk factors that may predispose athletes to ACL injury.Level of EvidenceLevel Ⅲ.