bluuebunny/crossref_metadata_2025_split huggingface dataset:
Vivências no processo de aleitamento materno de mães de recém-nascidos prematuros internados em um hospital público do município de Guarapuava-PR
Authors: Cabreira da Silva Tortorella Catiuscie , Cremasco Bruna Reis , Protcz Gabriele , Chuproski Saldan Paula , Komechen Brecailo Marcela , Zanellato Carla , Protcz Emanuele 
Published: March 2024

Objetivo: Descrever os relatos de vivências no processo de amamentação de mães de recém-nascidos prematuros. Método: Estudo qualitativo realizado com mães de recém-nascidos prematuros, internados em uma Unidade de Terapia Intensiva Neonatal, de um hospitalpúblico de Guarapuava-PR, no período de junho a julho de 2018, mediante aplicação de um instrumento com questões fechadas e outro com questões relacionadas à amamentação de prematuros. Foram incluídas no estudo mães que já haviam amamentado seus filhos ao seio ou por meio da ordenha mamária, e excluídas mães com idade inferior a 18 anos ou que apresentavam condições clínicas que as impediam de amamentar, cujos filhos estavam internados em período menor que três dias. Resultados: Participaram do estudo 10 mães de recém-nascidos prematuros, das quais 70% tinham idade gestacional de 32 a 36 semanas, 10% de 28 semanas e 20% de 29 semanas gestacionais. As mães relataram dificuldades em manter a pega e a sucção do leite materno e sentimentos de nervosismo, receberam apoio dos profissionais e familiares no incentivo à amamentação e no cuidado humanizado pela equipe de saúde. Conclusões: Diante do conhecimento das dificuldades encontradas pelas mães na amamentação de prematuros, é possível estabelecer medidas para evitar o desmame precoce, respeitando a autonomia da mãe no cuidado ao bebê.
Lower extremity peripherally inserted central catheter placement ectopic to the ascending lumbar vein: A case report
Authors: Zhu Xiao-Ju , Zhao Ling , Peng Na , Luo Jia-Min , Liu Shui-Xia 
Published: March 2024

BACKGROUND
Peripherally inserted central catheters (PICCs) are an essential infusion route for oncology patients receiving intravenous treatments, but lower extremity venipuncture is the preferred technique for patients with superior vena cava syndrome (SVCS). We report the case of a patient with a lower extremity PICC ectopic to the ascending lumbar vein, to indicate and verify PICC catheterisation in the lower extremity is safe and feasible. And hope to provide different perspectives for clinical PICC venipuncture to get the attention of peers.
CASE SUMMARY
On 24 August 2022, a 58-year-old male was admitted to our department due to an intermittent cough persisting for over a month, which worsened 10 d prior. Imaging and laboratory investigations suggested the patient with pulmonary malignancy and SVCS. Chemotherapy was not an absolute contraindication in this patient. Lower extremity venipuncture is the preferred technique because administering upper extremity venous transfusion to patients with SVCS can exacerbate oedema in the head, neck, and upper extremities. The patient and his family were informed about the procedure, and informed consent was obtained. After successful puncture and prompt treatment, the patient was discharged, experiencing some relief from symptoms.
CONCLUSION
Inferior vena cava catheterisation is rare and important for cancer patients with SVCS, particularly in complex situations involving ectopic placement.
Clinical manifestations and the prenatal diagnosis of trisomy 7 mosaicism: Two case reports
Authors: Hou Fei , Li Yan , Jin Hua 
Published: March 2024

BACKGROUND
The clinical manifestations of trisomy 7 mosaicism are diverse and nonspecific, so prenatal diagnosis is very difficult.
CASE SUMMARY
Two pregnant women with abnormal prenatal screening results were included. One was a 22-year-old woman (G1P0). At 31st week of gestation, ultrasound revealed that the posterior horn of the left lateral ventricle was 10 mm and the right renal pelvis had a separation of 7 mm. The other pregnant woman was 33 years old (G2P1L1A0), and her fetus was found to have a cardiac malformation at the 24th week of gestation. Copy number variation sequencing, whole-exome sequencing and karyotype analysis were carried out after amniocentesis, and both fetuses were diagnosed with trisomy 7 mosaicism. After parental counseling, one woman continued the pregnancy, and the other woman terminated the pregnancy.
CONCLUSION
In trisomy 7 mosaicism, the low proportion of trisomy does not lead to abortion, but can result in abnormal fetal development, which can be detected via ultrasound. Therefore, clinicians need to pay more attention to various aspects of fetal growth and development, combining with imaging, cellular, molecular genetics and other methods to perform comprehensive evaluations of fetuses to provide more reliable genetic counseling for pregnant women.
First knee for pain and function versus second knee for quality of life
Authors: Lewin Adriane M. , Cashman Kara , Harries Dylan , Ackerman Ilana N. , Naylor Justine M. , Harris Ian A. 
Published: March 2024

AimsThe aim of this study was to describe and compare joint-specific and generic health-related quality of life outcomes of the first versus second knee in patients undergoing staged bilateral total knee arthroplasty (BTKA) for osteoarthritis.MethodsThis retrospective cohort study used Australian national arthroplasty registry data from January 2013 to January 2021 to identify participants who underwent elective staged BTKA with six to 24 months between procedures. The primary outcome was Oxford Knee Score (OKS) at six months postoperatively for the first TKA compared to the second TKA, adjusted for age and sex. Secondary outcomes compared six-month EuroQol five-dimension five-level (EQ-5D-5L) domain scores, EQ-5D index scores, and the EQ visual analogue scale (EQ-VAS) between knees at six months postoperatively.ResultsThe cohort included 635 participants (1,270 primary procedures). Preoperative scores were worse in the first knee compared to the second for all instruments; however, comparing the first knee at six months postoperatively with the second knee at six months postoperatively, the mean between-knee difference was minimal for OKS (-0.8 points; 95% confidence interval (CI) -1.4 to -0.2), EQ-VAS (3.3; 95% CI 1.9 to 4.7), and EQ-5D index (0.09 points; 95% CI 0.07 to 0.12). Outcomes for the EQ-5D-5L domains ‘mobility’, ‘usual activities’, and ‘pain/discomfort’ were better following the second TKA.ConclusionAt six months postoperatively, there were no clinically meaningful differences between the first and second TKA in either the joint-specific or overall generic health-related quality of life outcomes. However, individual domain scores assessing mobility, pain, and usual activities were notably higher after the second TKA, likely reflecting the cumulative improvement in quality of life after both knees have been replaced.Cite this article: Bone Jt Open 2024;5(3):202–209.
The prevalence of non-contrast CT imaging abnormalities in reversible cerebral vasoconstriction syndrome: A systematic review and meta-analysis
Authors: Gotesman Ryan Daniel , Niznick Naomi , Dewar Brian , Fergusson Dean A. , Mallick Ranjeeta , Shorr Risa , Shamy Michel , Dowlatshahi Dar 
Published: March 2024

Background
Reversible cerebral vasoconstriction syndrome (RCVS) is a syndrome of recurrent thunderclap headaches and reversible vasoconstriction of the cerebral arteries on neuroimaging within 3 months of onset. Initial non-contrast computed tomography (CT) can reveal abnormalities such as ischemic stroke, intracerebral hemorrhage, and subarachnoid hemorrhage (SAH) can be present in patients with RCVS and may delay diagnosis.

Aims
We conducted a systematic review and meta-analysis in accordance with the PRISMA guidelines. We aimed to estimate the prevalence of imaging abnormalities on initial non-contrast CT head in adult patients with RCVS.

Data sources & eligibility criteria
We searched electronic databases including MEDLINE, EMBASE, and the Cochrane Register of Clinical Trials from inception to August 2, 2022. Eligible studies included articles reporting the prevalence of non-contrast CT abnormalities on initial neuroimaging in patients with RCVS, aged 18 and older. Case series, observational studies and clinical trials were included. Data was extracted directly from included papers using a standardized data charting form.

Results
The search yielded 722 titles with duplicates removed. Twenty studies that included 379 patients with RCVS met inclusion criteria. We classified non-contrast CT abnormalities as either ischemic stroke, ICH, or SAH. We pooled prevalence data using a random effects model with the inverse-variance weighted method. The most common imaging finding was SAH with a pooled prevalence of 24% (95% CI:17%-33%), followed by ICH at 14% (95% CI:8%-22%), and ischemic stroke at 10% (95% CI:7%-14%). The pooled prevalence of any of these imaging abnormalities on initial non-contrast CT was 31% (95% CI:23%-40%). Risk of bias was moderate to very-high-risk for case-series and low-risk for observational studies.

Conclusion
Our review demonstrates that one-third of patients with RCVS will have an abnormality on initial non-contrast CT head, including either an ischemic stroke, ICH, or SAH. These findings highlight the diagnostic challenges of RCVS imaging and contribute to our understanding of this disease.
Retrospective study of patellar fractures and damage of accessory soft tissue based on MRI
Authors: Hua Yi-Fan , Zhang Yu-Rou , Guo Li 
Published: March 2024

Background
To better understand the pathophysiological mechanisms of patellar fractures, MRI was utilized to identify the imaging signs of various types of patellar fractures.

Methods
A retrospective study was performed using MRI images of 52 patients with patellar fractures. Observing the development of patellar and femoral morphology and the imaging manifestations of different fracture types, such as fracture displacement, and damage to accessory ligaments, tendons, and meniscus, type of joint cavity effusion, and damage to surrounding accessory bones were identified.

Results
There were 21 tangential fractures (40.4%), 8 transverse fractures (15.4%), 8 longitudinal fractures (15.4%), 4 oblique fractures (7.7%), and 11 comminuted fractures (21.2%) among the 52 patients with patellar fracture. Tangential fractures begin at a younger age than the other four forms of fractures. When tangential fractures were compared to other types of fractures, medial patellar retinaculum and anterior and posterior cruciate ligament injuries were statistically significant (P< 0.05). The detection rate of trochlear dysplasia, type II and type III patellar was higher in patients with tangential fractures than in other fractures.

Conclusions
Tangential fractures are less common to cause anterior and posterior cruciate ligament injuries than other types of fractures, but they are more likely to cause medial patellar retinaculum injuries.
General practitioners’ experiences of providing lifestyle advice to patients with depression: A qualitative focus group study
Authors: Astaire Emma , Jennings Laura , Khundakar Martina , Silverio Sergio A. , Flynn Angela C. 
Published: March 2024

Objective
Depression is an increasingly common mental health disorder in the UK, managed predominantly in the community by GPs. Emerging evidence suggests lifestyle medicine is a key component in the management of depression. We aimed to explore GPs’ experiences, attitudes, and challenges to providing lifestyle advice to patients with depression.

Method
Focus groups were conducted virtually with UK GPs (May-July 2022). A topic guide facilitated the discussion and included questions on experiences, current practices, competence, challenges, and service provision. Data were analysed using template analysis.

Results
‘Supporting Effective Conversations’; ‘Willing, but Blocked from Establishing Relational Care’; ‘Working Towards Patient Empowerment’; and ‘Control Over the Prognosis’ were all elements of how individualised lifestyle advice was key to the management of depression. Establishing a doctor-patient relationship by building trust and rapport was fundamental to having effective conversations about lifestyle behaviours. Empowering patients to make positive lifestyle changes required tailoring advice using a patient-centred approach. Confidence varied across participants, depending on education, experience, type of patient, and severity of depression.

Conclusions
GPs play an important role in managing depression using lifestyle medicine and a patient-centred approach. Organisational and educational changes are necessary to facilitate GPs in providing optimal care to patients with depression.
Correlation of handgrip strength with quality of life-adjusted pulmonary function in adults
Authors: Jung Hae In , Gu Kang-Mo , Park So Young , Baek Moon Seong , Kim Won Young , Choi Jae-Chol , Shin Jong-Wook , Kim Jae-Yeol , Chang Young D. , Jung Jae-Woo 
Published: March 2024

Background
Handgrip strength (HGS) is acknowledged as a key indicator of overall physical fitness and is associated with various health outcomes.

Objectives
This research investigates the correlation between HGS and quality of life (QoL), focusing on its relation to pulmonary function in the general adult population.

Method
The study involved 19,402 participants aged 40 and above, spanning from 2014 to 2019, who underwent pulmonary function and HGS tests. Participants were categorized based on lung function, and regression analyses were employed to examine the relationship between HGS and QoL, with adjustments made for lung function.

Results
The average age of the cohort was 58.2 years, comprising 44.6% males and 41.2% smokers. Out of the 18,708 participants who completed the European Quality of Life Scale-Five Dimensions (EQ-5D-3L) assessment, higher severity levels in mobility, self-care, usual activities, pain or discomfort, and anxiety or depression were linked to lower HGS in both sexes. Additionally, among the 3,723 participants who completed the Health-related Quality of Life Instrument with 8 Items (HINT-8) assessment, higher severity levels in pain, work, and depression were associated with lower HGS in men. In women, higher severity levels in climbing stairs, pain, vitality, and work correlated with lower HGS.

Conclusions
As problems indicated by EQ-5D worsened, there was a consistent decrease in handgrip strength (HGS) across both genders. The HINT-8 assessment further revealed that increased severity in pain and work-related issues led to reduced HGS in both men and women. This study highlights the relationship between HGS and Quality of Life (QoL), taking lung function into consideration, and underscores the importance of HGS as a potential marker of physical health and fitness.
Four-Variable Jacobian Conjecture in a Topological Quantum Model of Intersecting Fields
Authors: De Miguel Bueno Alfonso 
Published: March 2024

This preprint introduces in a visual and conceptual way a model of two intersecting curved fields with a shared nucleus, whose quantized dynamics offer po tential cases of the four-variable Jacobian conjecture and a nonlinear Hodge cycle.
The Kummer type geometry of the model sug gests a unified framework where abstract mathemat ical developments like Tomita-Takesaki, Gorenstein, and Dolbeault theories, can be conceptually linked to the Jacobian, Hodge, and Riemann conjectures.
Other mathematical physics topics, like the mass gap problem, reflection positivity, the emergence of imaginary time, or t-duality, are also considered within this context.
The fields model also lies the foundation of a novel deterministic quantum atomic system with a super symmetric dual nucleus structure of matter and mir ror antimatter
SARAY BAHÇELERİNDEN KENT PARKLARINA SINIR VE SINIRSIZLIĞIN DEĞERLENDİRİLMESİ
Authors: ADA Elvan 
Published: March 2024

İnsanın çevresini tasarlama ve inşa etme becerisinin dününün ve bugününün incelenmesi, gelecekte yapılacak tasarım ve planlamaların ne şekilde kurgulanabileceği ile ilgili ipuçları barındırmaktadır. Bu bağlamda, insan ve doğanın ortak eserlerinden oluşan ve kültürel peyzaj alanları tanımı içerisinde yer alan saray bahçeleri ve kent içi parkların geçirdiği tarihsel sürecin değerlendirilmesi önem arz etmektedir.
Avrupa’da Rönesans düşüncesi ile beraber insanın doğa üzerindeki hakimiyeti, bahçe tasarımlarında kendini göstermeye başlamıştır. 16. yüzyılın ikinci yarısına doğru bahçeler, içinde yaşanacak bir mekân olmaktan çok lüks ve gösterişe yönelen alanlar olarak gelişmeye başlamış, monarşinin mutlak gücünün temsili bahçelerde yansımalarını bulmuştur. Avrupa’da bahçe mimarisi İtalya’daki Rönesans Bahçelerinden ilham alarak gelişmiş; 17. yüzyılda Fransız “Büyük Stiline “evrilerek sonraki yüzyılda, natüralistik peyzaj stiliyle doğal unsurların hâkim olduğu bir bahçe anlayışına dönüşmüştür. İmparatorlukların yıkılmaya başladığı, 19. yüzyılın Avrupası’nda, Endüstri Devrimini takiben sanatçı ve felsefecilerin söylemlerinden ilham alan kent parkları, kamusal buluşma mekanları olarak inşa edilmeye başlanmıştır. Osmanlı İmparatorluğu sınırlarında ise Avrupa’daki bahçe sanatı anlayışına benzer bir yaklaşım ancak 18. yüzyılda görülmeye başlamıştır.
Çalışmada, 16. yüzyılda Avrupa’da ve 18. yüzyılda Osmanlı İmparatorluğu’nda hanedan ve yakınlarının kullanımı için inşa edilmeye başlanan saray bahçelerinin siyasal, sosyal ve kültürel dinamiklerin etkisi ile günümüze dek geçirdiği değişim süreci ele alınmıştır. Bu kapsamda, Avrupa’dan Luxemburg Bahçeleri, Osmanlı İmparatorluğu Döneminden ise Yıldız Sarayı Bahçeleri örnek olarak seçilmiş ve incelenmiştir. Seçilen bahçe ve parklar ile ilgili, inşa edildiği dönem ile günümüzdeki kullanım koşulları, işlevleri ve tasarım dili çerçevesinde arşiv araştırması yapılmış; elde edilen veriler, yerinde gözlem sonucu değerlendirilmiştir.
Araştırmada, hanedanın kullandığı ve mutlak gücün simgesi olarak inşa edilen saray bahçelerinin, aynı zamanda dönemin kültürleşme sürecinin de somut örneklerini oluşturduğuna yönelik bilgilere ulaşılmıştır. Yüzyıllarca, halk ve hanedan arasında sınır teşkil eden bahçe duvarları yerini halkın geçişine imkân veren açık kapılara bırakmış, halkın rekreatif ihtiyaçlarını karşılayan kent içi parklar tesis edilmiştir. Bu hususlara yönelik elde edilen bilgiler ışığında, sınır ve sınırsız kavramlarının simgesel anlamının tartışıldığı bir yaklaşım sunulmuştur.
Congenital Zika virus infection impacts on male mouse offspring’s reproductive biology
Authors: Wnuk Natália Teixeira , Figueiredo André Felipe Almeida , de Oliveira Farias Talita , Brener Marcos Rocha Gouvêa , Lacerda Samyra Maria dos Santos Nassif , Camargos Vidyleison Neves , Amaral Paulo Henrique , Andrade Lídia Maria , Silva Maria Ivonete Nogueira , Lopes Roberta Araujo , Szawka Raphael Escorsim , González Juan Carlos , Teixeira Mauro Martins , de Souza Danielle da Glória , Costa Vivian Vasconcelos , Costa Guilherme Mattos Jardim 
Published: March 2024

In brief
Congenital ZIKV infection promotes alarming effects on male offspring's reproductive biology. This study showed the presence of the ZIKV antigen in the testis parenchyma, decreased testosterone levels, and sperm abnormalities in male offspring born to infected mothers.

Abstract
Infection with ZIKV during pregnancy is associated with fetal developmental problems. Although neurological issues are being explored more in experimental studies, limited research has focused on the reproductive health consequences for offspring born to infected mothers. In this context, this study aimed to assess the impact of ZIKV infection during pregnancy on the testes and sperm of adult male offspring. Female mice were intraperitoneally inoculated with a Brazil strain of ZIKV during the 5.5th day of embryonic gestation. The offspring were evaluated 12 weeks after birth to analyze cellular and molecular changes in the testes and sperm. A novel approach combining variable-angle spectroscopic ellipsometry and machine learning modeling was also introduced for sperm sample analysis. The study revealed the presence of ZIKV protein in the testis parenchyma of adult male offspring born to infected mothers. It was shown that the testes exhibited altered steroidogenesis and inflammatory mediators, in addition to significant issues with spermiogenesis that resulted in sperm with DNA fragmentation, head defects, and protamination failure. Additionally, sperm dielectric properties and artificial intelligence showed potential for rapid identification and classification of sperm samples from infected mice. These findings provide crucial insights into the reproductive risks for men born from ZIKV-infected pregnant women.
Disain Purwarupa Model Smart-Living berbasis Cloud
Authors: Akbar Rufman Iman 
Published: March 2024

Digitalisasi dan interkoneksi smart device (perangkat pintar) dapat memberikan berbagai keuntungan kepada manusia dalam kehidupan sehari-hari. seperti misalnya kenyamanan, keamanan serta penggunaan energi yang lebih efisien. Konsep smart living yang membungkus digitalisasi dan interkoneksi ini sejatinya adalah otomatisasi pada berbagai aspek kehidupan, mulai dari hunian, transportasi, hingga keseluruhan kota. Konsep ini hadir sebagai bagian dari teknologi IoT (Internet of Things). Perkembangan teknologi saat ini, memberikan kemudahan dalam mendisain dan mengimplementasikan konsep smart living dalam kehidupan sehari-hari. Perangkat keras, perangkat lunak, dan juga infrastruktur yang relatif semakin terjangkau, memungkinkan pengguna untuk membangun model smart living yang sesuai dengan kebutuhan mereka. Beberapa kebutuhan dasar smart living, seperti kamera pengawas yang dapat dikontrol dari jauh, kemampuan mengendalikan berbagai peralatan rumah tangga melalui sistem cloud (penyimpanan awan), dan juga perangkat keamanan yang relatif terjangkau dan dapat dintergrasikan dengan peralatan lainnya, membuat penerapan smart living semakin mudah. Penelitian ini mencoba membangun satu model purwarupa smart living dengan memadukan berbagai smart device sesuai kebutuhan tersebut
Experimental verification of the extended Einstein-Lorentz mass formula: Emission of abnormal electrons with energy up to 790TeV detected at downstream of RF cavity of electron storage ring of BEPCII
Authors: Qian Dapeng 
Published: March 2024

Abstract
In a new version of special relativity that incorporates the uncertainty principle, the Einstein-Lorentz mass formula is extended more completely. The new formula shows that there is a weak "high-speed but low-mass" effect in particles movement, which will cause the generation of abnormal ultra-high energy electrons with a computable small probability when the electron beam passes through an accelerating electric field. This previously unknown anomaly was tested on the electron storage ring of BEPCII by the author with a cumulative detection method, and results show that there is indeed the emission of electrons with energy up to 790TeV at downstream of the RF cavity, which is consistent with the theoretical expectation. On this basis, it is suggested that particle physicists do more experimental detection, so as to further fully verify the extended Einstein-Lorentz mass formula.