bluuebunny/crossref_metadata_2025_split huggingface dataset:
Isolated laryngeal lymphoma
Authors: Anderson H. Allen , Maisel Robert H. , Cantrell Robert W. 
Published: September 2006

AbstractIsolated laryngeal lymphoma is a rare occurrence. We found a total of 14 previously reported cases. These plus our additional case are reviewed in order to make recommendations for diagnosis, therapy, and follow‐up.Histologic classification and clinical staging of lymphomas have limited usefulness, because the tumor can change cell type during the clinical course of the disease.Once histologic proof of the tumor exists, adequate evaluation consists of physical examination to detect adenopathy elsewhere, bone marrow biopsy, urinalysis, blood uric acid levels, liver biopsy, and liver and kidney function tests. The search must continue in the chest by X‐ray, the retroperitoneal nodes by lymphangiography and the abdominal visera by contrast radiography.Radiation therapy is the best initial treatment for isolated laryngeal lymphoma. If the tumor does not respond to irradiation, then operation to remove the lesion is required. This tumor has a tendency to recur at distant sites many years later. As with all cancer patients life‐long follow‐up is required.
Cervical hibernoma
Authors: Lawson William , Biller Hugh F. 
Published: September 2006

AbstractThe hibernoma is a rare neoplasm derived from vestigial remnants of brown fat left from early embryologic development. Review of the world literature reveals only 40 cases to which we are adding a report of a tumor arising in the posterior cervical triangle of a 20‐year‐old man. The distribution, histology and cytochemistry of brown fat and the hibernoma are discussed, and evidence supporting its histogenesis is presented.
Human cochlear changes in noise induced hearing loss
Authors: Mcgill Trevor J. I. , Schuknecht Harold F. 
Published: September 2006

AbstractThe temporal bone histopathological findings in 14 ears with noise induced hearing loss are presented. The morphological changes consist mainly of hair cell loss, which is more severe in the 9 mm to 13 mm region of the cochlear duct. Within the area of maximum hair cell loss, there is a greater loss of outer hair cells than of inner hair cells. There is a good correlation between the permanent auditory threshold shifts and the spatial location of the sensory lesion according to the anatomical frequency scale.
Chondrodermatitis helicis: A clinical re‐evaluation and pathological review
Authors: Metzger Steven A. , Goodman Max L. 
Published: September 2006

AbstractChondrodermatitis helicis, or painful nodule of the ear, is an uncommon benign aural lesion which is seen and treated by dermatologists and otolaryngologists. Because of the sparcity of reports in the recent literature, our experience with 50 patients over a 10‐year period is presented.The diagnosis is based on history and physical examination and biopsy need be performed only to confirm the diagnosis in atypical cases. Patients are generally middle‐aged or elderly males. There are no associated systemic disorders with this condition. The lesions are discrete, grey to red in color, oval shaped with raised rolled edges, and a central ulcer or depression which often contains a crust or scale. The lesion is typically painful and tender and, for this reason, the patient seeks help shortly after the onset of symptoms. The characteristic histopathologic features are epithelial hyperplasia, collagen degeneration, focal fibrinoid necrosis, and inflammatory components.Clinically, the lesion is misdiagnosed in the majority of instances and is presumably, therefore, treated inappropriately. It should be stressed that this is a benign condition and initial management should be aimed at conservative therapy with local steroid injection or conservative non‐deforming surgery. Wide excision, including removal of the underlying cartilage with appropriate reconstructive closure should be reserved for the conservative treatment failures.
Bifid epiglottis: A rare laryngeal anomaly
Authors: Healy Gerald B. , Holt Gordon P. , Tucker John A. 
Published: September 2006

AbstractTwo cases of bifid epiglottis are presented: one with an associated laryn‐geal cyst and another with an associated cricoid stenosis. The occurrence of multiple laryngeal anomalies in association with bifid epiglottis has not previously been described. The occurrence of an extra digit is noted to be statistically significant both in the current series and in a review of the literature. A brief review of the embryologic classification and staging by the Carnegie System, and the correlation of the time sequence of development of the epiglottis is presented. No correlation is made as to the mechanism of the origin of this laryngeal anomaly, as adequate embryologic knowledge of the development of the pharynx is not available at this time.
Patterns of anomalies in children with malformed ears
Authors: Rapin Isabellb , Ruben R. J. 
Published: September 2006

AbstractSixteen children with anomalies of the auricle and/or middle ear who presented malformations of the face, mouth, upper airway, spine, limbs, heart, gastrointestinal (GI), and/or genitourinary (GU) systems, were described. While clusters of anomalies suggested syndromes such as the oculo‐auriculo‐vertebral syndrome of Goldenhar, hemifacial microsomia, mandibulo‐facial dysostosis (Treacher Collins syndrome), Pierre Robin, Klippel‐Feil, Moebius, Duane, and/or VATER syndromes, many children did not fit what are usually considered even minimal criteria for these syndromes. Several children had malformations which fit the description of more than one syndrome.The importance of investigating the children for unsuspected anomalies, especially of the GU system, was emphasized. Life threatening problems in this group consisted of airway problems, congenital heart disease, and major anomalies of the GI and GU systems. Better management of sucking, swallowing and airway problems might have decreased the early morbidity and mortality (3/16) in this group.Children with multiple defacing anomalies may not be mentally retarded so that aggressive management of their visceral anomalies and hearing problems, and early educational intervention are mandatory. Delay in development may be due to hearing loss, vestibular impairment, ataxia, the consequences of early malnutrition, and multiple hospitalizations rather than to mental retardation. A pessimistic attitude in infancy is unwarranted since it is impossible to predict which children will end up competitive individuals.
Recurrent meningitis secondary to idiopathic oval window csf leak
Authors: Parisier Simon C. , Birken Eric A. 
Published: September 2006

AbstractBacterial meningitis remains a life‐threatening infection even in the present antibiotic era; thus, any abnormality which predisposes a patient to a recurrence of this serious disease, must be identified and corrected. This report describes the history of a 12‐year‐old boy with a profound neurosensory hearing loss, a related absence of vestibular function and a Monclini‐type of temporal bone dysplasia who developed recurrent episodes of meningitis which were due to an idiopathic cerebrospinal fluid otorrhea. Even though the meningitis was labyrinthogenic in origin, the patient did not experience the associated symptoms of hearing loss and/or vertigo since the affected inner ear was clinically unreactive. By surgically exploring the middle ear, the presence of a cerebrospinal fluid otorrhea was confirmed. The leak was observed to be coming from a defect in the stapes footplate, and it was controlled by firmly packing the inner ear vestibule with muscle.A remarkable similarity exists between the patient described above and the 15 previously reported cases of meningitis due to a spontaneous cerebrospinal fluid otorrhea. Generally, the problem occurred in young children, the average age being 6.4 years; male and female were equally afflicted. All 15 previously reported cases had a severe neurosensory hearing loss which was unilateral in 10 individuals and bilateral in the other five. In 11 of the case reports, the vestibular function was evaluated, and the labyrinth was noted to be unreactive in the affected ear. An associated congenital abnormality of the inner ear was described in 11 of the patients reviewed.Anatomically, in 13 cases, the leak was observed to be coming from the oval window area. Other affected sites included one report of a fissure of the promontory and one report of a defect in the roof of the eustachian tube.Multiple surgical procedures were required in 11 of the 15 patients in order to identify the exact source of the otorrhea and to seal it permanently. In three cases, the successful procedure was a middle ear exploration with stapedectomy and packing of the inner ear vestibule. Overall, a total of 36 operations was performed in the 15 patients reviewed.In conclusion, when the physician is confronted by a case of meningitis in a patient with a unilateral or bilateral total loss of hearing and vestibular function, the possible presence of an idiopathic cerebrospinal fluid leak should be considered, especially if radiographic studies demonstrate a temporal bone dysplasia. In these selected cases, if the etiology of the meningitis is obscure, a middle ear exploration should be performed both for diagnostic purposes as a means to ascertain definitely the presence of a leak and for therapeutic purposes to seal it effectively.
Office otology follow‐up
Authors: Caparosa Ralph J. , Shamblin Jerry D. 
Published: September 2006

AbstractThe validation of otological care in the previous quarter century has been based, by and large, on short‐term follow‐up information. The rapid variation in procedures introduced during this period indicates that there may be need for further consideration. Analyses based on relatively short duration have led to the “acceptance” of a variety of diagnostic and treatment methods which have proven disappointing in some cases. To help avoid this invalid “acceptance,” a review of patients with significant follow‐up may result in a more critical evaluation of future procedural changes.This presentation will be in four parts:

History of the office structure.
Discussion of five long‐term patients that illustrates and supports certain otological concepts.
A review of surgical care for chronic suppurative otitis media in 1968.
A review of patients treated for serous otitis media with myringotomy and tubal insertion in 1968.
Globus hystericus — office evaluation by psychological testing with the mmpi
Authors: Pratt Loring W. , Tobin Wayne H. , Gallagher Ruth A. 
Published: September 2006

AbstractNinety‐nine patients, twenty‐three men and seventy‐six women, who complained of a lump in the throat were evaluated with the Minnesota Multiphasic Personality Inventory, which revealed that these patients had a higher than average score on the depression and the hypochondriasis scales. The intensity of this finding was greater in males. One must never overlook the possibility of a neurotic patient also having serious organic disease.
Rhinosporidiosis
Authors: Kutnick Steven L. , Kerth Jack D. 
Published: September 2006

AbstractA case of rhinosporidiosis occurring in an immigrant from India is presented along with a review of the disease. Rhinosporidiosis most commonly involves the nose, and presents as a friable papillomatous mass causing nasal obstruction, epistaxis, purulent discharge, and headache may also occur. The treatment of choice is surgical excision with cauterization of the base.
Medullary carcinoma of the thyroid
Authors: Fierstein Jeffrey , Sessions Donald G. , Thawley Stanley E. , Ogura Joseph H. 
Published: September 2006

AbstractMedullary carcinoma is an unusual malignant neoplasm. The cell of origin is considered to be the C‐cell which is derived from the ultimo‐branchial body and neural crest. The tumor is solid and has characteristic amyloid in the stroma. The lesion usually presents as a neck mass, and multicentricity is not unusual. In some patients diarrhea may be an important presenting symptom. Serum calcitonin is typically elevated and is important in the diagnostic confirmation. About 10 percent of the cases are part of a familial endocrine syndrome which includes pheochromo‐cytomas, mucosal neuromas, and other endocrine gland adenomas. Frequent multicentricity and early cervical lymphatic and systemic metastases necessitate total thyroidectomy and radical neck dissection. Prognosis varies from a rapid demise to long term survival.
Beyond Dressing and Driving: Using Occupation to Facilitate Community Integration in Neurorehabilitation
Authors: Fleming Jennifer M. , Doig Emmah , Katz Noomi 
Published: September 2006

AbstractDuring the process of community integration, individuals with acquired brain injury may experience difficulties in all areas of occupational performance including self-care, home management, community access, leisure, social activities and vocational pursuits. Community based rehabilitation services provide opportunities to minimise such difficulties by working with clients as they engage in meaningful real-life context-based occupations. The therapeutic use of occupation is at the core of occupational therapy practice. We reflect on the nature and principles of occupation and highlight particular benefits for facilitating community integration after brain injury. This is illustrated using the example of executive dysfunction. Several challenges for the occupational therapy profession arise from the shift in focus from hospital to community based rehabilitation, and the need for further research on community integration after brain injury from an occupational perspective is recognised.
Understanding Social Support and Friendship: Implications for Intervention After Acquired Brain Injury
Authors: Rowlands Allison 
Published: September 2006

AbstractThis article reviews current literature on social support and friendship, loneliness and social isolation, and discusses these in the context of disability and specifically acquired brain injury. The examination provides a backdrop for considering interventions which aim to promote or regenerate friendships in the lives of people with this injury. The social consequences for individuals who have sustained an acquired brain injury have been well documented and are briefly reviewed. An understanding of the social support and friendship literature, reviewed in this article, is helpful for practitioners in designing interventions in the lives of this group of people, whose limited friendship and social support systems compromise quality of life and inclusion in the community. The article describes interventions that have been attempted to facilitate network building and friendship development for vulnerable or disadvantaged people in a wide range of contexts. The role of informal support systems is also discussed. A critique of these interventions is also presented and the conclusion reached is that while such models are not perfect and are often not rigorously evaluated, it is critical to provide assistance in order to achieve genuine social inclusion of people with acquired brain injury. It is their human right.
Monitoring Recovery of Cognitive Function Following Severe Traumatic Brain Injury
Authors: Wilson Barbara A. , Shiel Agnes , McLellan Lindsay , Horn Sandra , Watson Martin A. 
Published: September 2006

AbstractWe report on the development of a new assessment tool to monitor recovery after severe traumatic brain injury (TBI). Although a number of scales exist to identify such recovery, most are limited if one is interested in monitoring small changes or in setting goals for rehabilitation. This is due to the fact that items are too broad, they may cross more than one dimension (e.g. cognition and motor functioning) and there is a danger that recording of responses may be too subjective. The Wessex Head Injury Matrix (WHIM) was developed to avoid these problems. We observed 88 people with severe TBI. These were consecutive admissions to two hospitals. Mean coma duration was 14 days and mean duration of post traumatic amnesia (PTA) was 56 days. Of 145 behaviours observed, we selected 62 and each behaviour was compared to every other behaviour to determine a likely order of recovery. The resulting WHIM is an observational tool to assess and monitor cognitive recovery after severe head injury. It can be used with patients who are in coma, just out of coma or who are minimally conscious. Two case examples are provided.
Fine‐Scale Genetic Structure of Bull Trout at the Southern Limit of Their Distribution
Authors: Whiteley Andrew R. , Spruell Paul , Rieman Bruce E. , Allendorf Fred W. 
Published: September 2006

AbstractWe used six polymorphic microsatellite loci to analyze the population genetic structure of bull trout Salvelinus confluentus in the Boise River, Idaho, and we compared our results with previous data from similarly sized river systems in western North America. Within the Boise River, we found low genetic variation within and significant differentiation among sample sites. Two cohesive groups of populations were associated with the two major subbasins in this system, which we attributed to long‐term reduction of gene flow or distinct sources of colonization at this scale. We observed a significant pattern of isolation by distance in one subbasin and not in the other; this result suggests that the relative influences of gene flow and drift have differed between the two subbasins. Ecologically defined patches of suitable habitat were not good predictors of genetic variation among samples. Dams and other anthropogenic barriers have recently changed the potential for gene flow and genetic drift but were not associated with the major boundaries of genetic differentiation. There was some evidence of lost genetic variation in smaller patches that were physically isolated by both natural and anthropogenic barriers. We found a large range of within‐population genetic variation and among‐population genetic differentiation for bull trout from river basins across the species' range, but our estimates in the Boise River were the lowest (or among the lowest) observed. The relative roles of drift and gene flow appear to vary strongly at both fine and broad spatial scales. We cannot presume that the physical and ecological processes influencing the genetic population structure of bull trout in one region will accurately reflect those in another region; this may have important implications for conservation and management actions.
Neonatal Care of Infants with Cleft Lip and/or Palate: Feeding Orientation and Evolution of Weight Gain in a Nonspecialized Brazilian Hospital
Authors: Amstalden-Mendes Lívia Gobby , Magna Luis Alberto , Gil-da-Silva-Lopes Vera Lúcia 
Published: September 2006

Objectives: To survey the feeding orientation received during the postnatal period by the parents of cleft babies, as well as the location where they receive the orientation; to identify resources used in feeding; and to assess the correlation of the child's weight with the surgical procedure schedule. Design: During consultation for diagnosis and genetic counseling in a general tertiary hospital, 26 parents of cleft babies born in different hospitals were interviewed based on a semistructured protocol and spontaneous reports. Results: Cleft palate was present in 42.31% (11/26), cleft lip/palate in 50% (13/26), and cleft lip in 7.69% (2/26) of the cases. Feeding orientation was given in maternities to 72% (18/25) and in specific rehabilitation centers to 24% (6/ 25) of the parents. Breast-feeding was encouraged in every case. Nevertheless, other feeding resources were necessary, especially bottles. Surgical procedure delays caused by poor weight gain occurred in 66.7% (12/18). Conclusions: Neonatal feeding orientation was not systematically given in every case. Because it is an important way to achieve an effective weight gain, educational programs for nonspecialized health professionals, as well as regular pediatric follow-up and specialized multi-professional teams, could improve nutritional intake and could move the schedule for surgical procedures forward. The results also suggest that specific neonatal health care for cleft babies should be part of health policy.
Anomalies in Near‐Infrared Spectroscopy
Authors: Ciurczak Emil W. 
Published: September 2006

Abstract
The sections in this article are

Introduction

Solid Samples

Sample Preparation

Grinding

Drying

Dissolving

Sample Presentation

“
As
‐
is
”

Sample Cups

Sample Transports

Liquid Samples

Sample Preparation

Degassing

Filtration

Dilution

Sample Presentation

Temperature Effects

Physical/Chemical Effects

Pressure

Flow Rates

Refractive Index

Conclusions
Applications of Vibrational Spectroscopy in Criminal Forensic AnalysisThis is publication number 01‐06 of the Laboratory Division of the Federal Bureau of Investigation. Names of commercial manufacturers are provided for identification only and inclusion does not imply endorsement by the Federal Bureau of Investigation.
Authors: Bartick Edward G. 
Published: September 2006

AbstractThe sections in this article areIntroduction to Forensic AnalysisGeneral Use of Vibrational Spectroscopy in Forensic AnalysisInfrared SpectroscopyRaman SpectroscopyPolymer AnalysisGeneral PolymersCopy TonersFibersPaintsTapesDrugsExplosivesSummary and Future DirectionAcknowledgments
Significance of case reports in the advancement of medical scientific knowledge
Authors: Carey John C. 
Published: September 2006

AbstractIn an Editorial Comment in 2006 Carey summarized the issues surrounding the publication of case reports in the current medical literature. In this present study, three questions about case reports are posed by the author: Do journals still publish single case reports? What do medical journals call these reports? And how should we classify reports of single clinical observations? The author examined the table of contents of 25 prominent journals and addressed the question as to whether these selected periodicals published case reports. The analysis showed that 32% of reviewed journals published case reports and 32% did not, while the remainder of journals published this class of papers but in a modified fashion and not regularly. Journals varied in what term they use to describe case reports. The author proposed a classification system for case reports in the human genetics literature. More dialogue and research is needed to examine the role of case reports in the medical scientific literature. © 2006 Wiley‐Liss, Inc.
Further evidence of MAO‐A gene variants associated with bipolar disorder
Authors: Müller Daniel J. , Serretti Alessandro , Sicard Tricia , Tharmalingam Subi , King Nicole , Artioli Paola , Mandelli Laura , Lorenzi Cristina , Kennedy James L. 
Published: September 2006

AbstractThe aim of this study was to investigate MAOA gene variants in bipolar disorder by using a family‐based association approach. The first sample included 331 nuclear families from Western and Central Canada with at least 1 offspring affected with bipolar disorder comprising a total of 1,044 individuals. All subjects were genotyped for MAOA–941T > G and −uVNTR gene variants using PCR techniques. Haplotype TDT was statistically significant (LRS = 12.17; df = 3; P = 0.0068; permutation global significance = 0.00098), with the T‐4 haplotype significantly associated with bipolar disorder (OR = 1.63, 95% CI = 1.11–2.37). Single marker analysis evidenced a borderline association for MAOA–941T > G (P = 0.04), but not for the uVNTR. Pooling the Canadian sample with a second previously reported Italian sample genotyped for the uVNTR variant, negative results were obtained as well. No different results were detected when analyzing female subjects separately. In conclusion, our family‐based association study gives mild but further support of the involvement of MAOA variants in bipolar disorder. © 2006 Wiley‐Liss, Inc.