bluuebunny/crossref_metadata_2025_split huggingface dataset:
Utopias Urbanas desde o Giro Decolonial
Authors: Limonad Ester , Monte-Mór Roberto Luís 
Published: April 2024

Nous reprenons un exercice théorique de réflexion sur les utopies urbaines, un urbain naturel, qui renvoient à des relations société-nature alternatives et à des projets utopiques de société équitables qui renforcent la solidarité sociale, d'autres rapports sociaux de production, d'autres formes de production de l'espace social (et différentiel) et d'autres formes de vie quotidienne capable de faire face à l'accumulation capitaliste. Dans une perspective latino-américaine contemporaine, il est impossible d'aborder les utopies urbaines et même les expressions possibles de l'urbain naturel si ce n'est dans une perspective critique par rapport à la colonialité. Cette tâche comporte donc un certain nombre d'étapes. Le premier concerne l'utopie, les utopies urbaines et la nature. La seconde est liée à la démystification de la modernité occidentale et d'autres conceptions de la relation société-nature, fondée sur le tournant décolonial. Et le troisième, basé sur Quijano, Walsh et Lefebvre, vise à mettre en évidence le rôle transformateur de la vie quotidienne ainsi que les modes alternatifs de production de la vie matérielle et de l'existence sociale.
Prognostic Implication of Right Ventricular Free Wall Longitudinal Strain and Right Atrial Pressure Estimated By Echocardiography in Patients With Severe Functional Tricuspid Regurgitation
Authors: Ogawa Mana , Kuwajima Ken , Yamane Takafumi , Hasegawa Hiroko , Yagi Nobuichiro , Shiota Takahiro 
Published: April 2024

Background
The interaction between right ventricular (RV) function and pulmonary hypertension is crucial for prognosis of patients with severe functional tricuspid regurgitation. RV free wall longitudinal strain (RVFWLS) has been reported to detect RV systolic dysfunction earlier than other conventional parameters. Although pulmonary artery systolic pressure measured by Doppler echocardiography is often underestimated in severe functional tricuspid regurgitation, right atrial pressure (RAP) estimated by echocardiography may be viewed as a prognostic factor. Impact of RAP and RVFWLS on outcome in patients with severe functional tricuspid regurgitation remains unclear. The aim of the present study was to investigate prognostic implication of RAP, RVFWLS, and their combination in this population.

Methods and Results
We retrospectively examined 377 patients with severe functional tricuspid regurgitation. RAP, pulmonary artery systolic pressure, RV fractional area change, and RVFWLS were analyzed. RAP of 15 mm Hg was classified as elevated RAP. All‐cause death at 2‐year follow‐up was defined as the primary end point. RVFWLS provided better prognostic information than RV fractional area change by receiver operating characteristic curve analysis. In the multivariable Cox regression analysis, elevated RAP and RVFWLS of ≤18% were independent predictors of clinical outcome. Patients with RVFWLS of ≤18% had higher risk of all‐cause death than those without by Kaplan–Meier curve analysis. Furthermore, when patients were stratified into 4 groups by RAP and RVFWLS, the group with elevated RAP and RVFWLS of ≤18% had the worst outcome.

Conclusions
Elevated RAP and RVFWLS of ≤18% were independent predictors of all‐cause death. The combination of elevated RAP and RVFWLS effectively stratified the all‐cause death.
CIBSE TM54 energy projections II: A case study using dynamic simulation with template systems modelling
Authors: Jain Nishesh , Burman Esfand , Mumovic Dejan 
Published: April 2024

CIBSE TM54 was recently revised and covers best practice methods to evaluate the operational energy use of buildings. TM54 is a guidance document on performance evaluation at every stage of the design and construction process, and during the occupied stage, to ensure that long-term operational performance is in line with the design intent. The main performance evaluation principles in TM54 are a step-by-step modelling approach and scenario testing, to improve the robustness of the design proposal calculations. The latest version brings an updated perspective to the modelling approaches, including dynamic simulation with Heating, Ventilation and Air Conditioning (HVAC) systems. It also incorporates more detailed guidance around risks, target setting, scenario testing and sensitivity analysis. A case study approach is used to explore some of the important aspects described in TM54. TM54 recommends three modelling approaches (aka implementation routes) that a project can follow depending on its scale and complexity: using quasi-steady state tools; using dynamic simulation with template HVAC system; and using dynamic simulation with detailed HVAC system modelling. As part of a series of three, this case study provides an application of the second implementation route: using dynamic simulation with template HVAC. This case study provides detailed guidance on undertaking CIBSE TM54 modelling and projecting design stage building performance. The study covers the interpretation and clarifications of how TM54 can be applied, through the dynamic modelling tools using template HVAC systems.
Pressure and stiffness of a new air-inflated compression wrap
Authors: Mosti Giovanni , Gasparis Antonios , Oropallo Alisha , Labropoulos Nicos 
Published: April 2024

Objective To report pressure and stiffness, in healthy volunteers, of a new compression device with an air bladder inflated by a pump to regulate pressure. Methods The device was applied to 60 legs of 30 volunteers and set to exert different pressures of 20–50 mmHg. The exerted pressure was measured in supine and standing positions and during simple physical exercises; static stiffness index, dynamic stiffness index, and walking pressure amplitudes were calculated. Results The exerted pressure showed a good correlation with the expected pressure at each pressure range. The stiffness indices were >10 mmHg in the range of inelastic materials. The device was considered very easy to apply and use by the testing researchers. Conclusions The device stiffness is in the same range as the inelastic bandages. Consequently, similar hemodynamic effectiveness could be expected but must be proved. Unlike inelastic bandages, this device was easy to apply and use.
Experiences with advance care planning in amyotrophic lateral sclerosis: Qualitative longitudinal study with people with amyotrophic lateral sclerosis and their family carers
Authors: Vandenbogaerde Isabel , Van den Block Lieve , Deliens Luc , Carduff Emma , van der Heide Agnes , De Bleecker Jan , De Vleminck Aline 
Published: April 2024

Background: It is unclear when people with amyotrophic lateral sclerosis and their family carers think about their future, what they would prefer in terms of care, and how their ideas change over time. Aim: Understanding experiences with advance care planning of persons with amyotrophic lateral sclerosis and their family carers—and if, when, how, and why these experiences change over time. Design: A qualitative longitudinal interview study. Analysis involved content analysis, followed by a two-step timeline method to describe changes in advance care planning experiences within and across participants. Setting/participants: Nine persons with amyotrophic lateral sclerosis and nine family carers who were interviewed three times over a 9-month period. Results: All participants thought about future care, but few talked about it. Over time, advance care planning experiences were influenced by intertwined elements: (1) experienced physical decline and related future care needs; (2) how persons with amyotrophic lateral sclerosis identify themselves as patients; (3) obtaining information about diagnosis and prognosis; (4) professionals initiating conversations about medical aspects of end-of-life decisions; (5) balancing between hope to remain stable and worry about the future; and (6) protecting themselves and each other from worries about the future. Conclusion: This study emphasizes how factors such as coping with the disease and relational dynamics shape individuals’ thoughts about future care over time and how psychological, social, and medical factors are interwoven in advance care planning. The findings advocate for a process-oriented perspective, portraying advance care planning as an ongoing dialog, encompassing the needs, concerns, and emotions of both people with amyotrophic lateral sclerosis and their family carers.
Comparison of MRI findings of hypothalamic-optic chiasmatic gliomas and craniopharyngiomas
Authors: Karaman Ahmet Kursat , Özgen Kerime Hatun , Korkmazer Bora , Hamid Rauf , Kübra Yıldırım Hatice , Kemerdere Rahşan , Çomunoğlu Nil , Tanrıöver Necmettin , Arslan Serdar , Kızılkılıç Osman 
Published: April 2024

Background Differential diagnosis of hypothalamic-optic chiasmatic gliomas (HOCGs) and craniopharyngiomas on magnetic resonance imaging (MRI) can be quite challenging. Purpose To compare the MRI features of HOCGs and cranipharyngiomas. Material and Methods Patients diagnosed with HOCG or craniopharyngioma in histopathological evaluation between 2012 and 2022 and who underwent preoperative contrast-enhanced brain MRI were included. Various MRI features were retrospectively evaluated for each lesion: T2-weighted imaging and fluid attenuation inversion recovery hyperintensity, calcification, cystic change, T1-weighted (T1W) imaging hyperintensity of the cystic component, hemorrhage, involvement of sellar, suprasellar or other adjacent structures, lobulated appearance, presence of hydrocephalus, and contrast enhancement pattern. Apparent diffusion coefficient (ADC) values were also evaluated and compared. Results Among 38 patients included, 13 (34%) had HOCG and 25 (66%) had craniopharyngioma. Craniopharyngiomas had a significantly higher rate of cystic changes, calcification, and T1W imaging hyperintensity of the cystic component than HOCGs ( P <0.05). Of HOCGs, 92% had chiasm involvement, 23% had optic nerve involvement, and 31% had brain stem involvement. On the other hand, chiasm involvement was observed in 8% of craniopharyngiomas, but none had optic nerve and/or brain stem involvement ( P <0.05). While 62% (8/13) of HOCGs had diffuse homogeneous enhancement, 80% (20/25) of craniopharyngiomas had a diffuse heterogeneous enhancement pattern. Mean ADC values were significantly higher in craniopharyngiomas compared to HOCGs (2.1 vs. 1.6 ×10−3mm2/s, P <0.05). Conclusion Although some neuroimaging findings may overlap, features such as presence of cyst and calcification, brain stem and optic pathway involvement, different enhancement patterns, and ADC values may be helpful in the differential diagnosis of HOCGs and craniopharyngiomas.
Chest CT radiomics is feasible in evaluating bone changes in chronic kidney diseases
Authors: Wu Gang , Yang Yongli , Liu Liangjin 
Published: April 2024

Background Non-invasive imaging methods are still lacking for evaluating bone changes in chronic kidney diseases (CKD). Purpose To investigate the feasibility of chest CT radiomics in evaluating bone changes caused by CKD. Material and Methods In total, 75 patients with stage 1 CKD (CKD1) and 75 with stage 5 CKD (CKD5) were assessed using the chest CT radiomics method. Radiomics features of bone were obtained using 3D Slicer software and were then compared between CKD1 and CKD5 cases. The methods of maximum correlation minimum redundancy (mRMR) and least absolute shrinkage and selection operator (LASSO) were used to establish a prediction model to determine CKD. The receiver operating characteristic (ROC) curve was used to determine the performance of the model. Results Cases of CKD1 and CKD5 differed in 40 radiomics features ( P <0.05). Using the mRMR and LASSO methods, five features were finally selected to establish a predication model. The area under the receiver operating characteristic curve of the model in the determination of CKD1 and CKD5 was 0.903 and 0.854, respectively, for the training and validation cohorts. Conclusion Chest CT radiomics is feasible in evaluating bone changes caused by CKD.
Using the PLUS Framework to support supervisors to make the most of practice education supervision: Experiences from Singapore
Authors: Dancza Karina M. , Hoo Corrine , Goh Xin En Jacintha , Tan Jervyn Charity , Shu Hui Lee , Lagui Masaoy Rialyn Fae , Chooi Yin Ong , Pei Qi Pay , Yong Mei Xing Sharmaine 
Published: April 2024

Introduction: Practice education is a crucial component of occupational therapy education, providing students with hands-on experience in real-world settings. Supervisors play a vital role in shaping students’ learning experiences, and the Professional Learning through Useful Support Framework, developed in the United Kingdom, serves as a guide for supervisors. However, its applicability in different cultural contexts remains uncertain. This qualitative study explores the perspectives and experiences of supervisors in Singapore who used the Professional Learning through Useful Support Framework to guide their supervision of students. Method: Nine new and five experienced supervisors participated in semi-structured interviews, during a 7-week practice education period. Interviews were transcribed and analysed using template analysis. Findings: Three themes were developed: The Professional Learning through Useful Support Framework brought awareness to supervisors’ supervisory techniques and guided their actions; The Professional Learning through Useful Support Framework gave permission to use a range of supervisory strategies; and The Professional Learning through Useful Support Framework could be used as a catalyst for enhancing support for supervisors. Conclusion: The Professional Learning through Useful Support Framework positively influenced supervisor communication and encouraged a purposeful approach to student supervision. Challenges emerged in implementing the concept of ‘safe failure’ due to cultural attitudes towards success, necessitating cultural adaptation. The study suggests introducing educational opportunities and ongoing support to use the Framework to enhance supervisor skills.
The non-decussating and decussating trigeminothalamic tracts in humans: A combination of connectome-based tractography and histological validation
Authors: Henssen Dylan J.H.A. , Pritsch Cynthia , Nazari Pouyan , Mulleners Wim , Vissers Kris 
Published: April 2024

Background Functional anatomical research proposed the existence of a bilateral trigeminal ascending system although the anatomy trajectories of the trigeminothalamic connections cranial to the pons remain largely elusive. This study therefore aimed to clarify the anatomical distributions of the trigeminothalamic connections in humans. Methods Advanced deterministic tractography to an averaged template of diffusion tensor imaging data from 1065 subjects from the Human Connectome Project was used. Seedings masks were placed in Montreal Neurological Institute standard space by use of the BigBrain histological dataset. Waypoint masks of the sensory thalamus was obtained from the Brainnetome Atlas. Results Tractography results were validated by use of the BigBrain histological dataset and Polarized Light Imaging microscopy. The trigeminothalamic tract bifurcated into a decussating ventral and a non-decussating dorsal tract. The ventral and dorsal tracts ascended to the contralateral thalamus and ipsilateral thalamus and reflected the ventral trigeminothalamic tract and the dorsal trigeminothalamic tract, respectively. The projection of the ventral trigeminothalamic tract and the dorsal trigeminothalamic tract to both thalami confirm the existence of a bilateral trigeminothalamic system in humans. Conclusions Because our study is strictly anatomical, no further conclusions can be drawn with regard to physiological functionality. Future research should explore if the dorsal trigeminothalamic tract and the ventral trigeminothalamic tract actually transmit signals from noxious stimuli, this offers potential in understanding and possibly treating neuropathology in the orofacial region.
‘Monkeypox 2.0’: Case series on a reconditioned virus causing sexually transmissible disease in urban population
Authors: Pakran Jaheersha , Alsaberi Amal Mohammed , AlFalasi Amani , Ibrahim Tarek Mohamed Karam Husein , Alnuaimi Amel Abdalla Eisa Fadl , Goturu Srikumar , Mohamed Muneer , Abraham Reena Mary , Sundaramurthi Vidya Lakshmi , Parambath Aneesh Kunnath , Jose Beena , Kamat Divya , Satish Thencheri Cheriath , Syeda Juwariya Tasneem , Gul Lubna , Mathias Rohini , Rasheed Vattiyamveetil Sajeela , Backar Shaheela , Krishna C Vijay , Al Dhabal Laila 
Published: April 2024

Background MPOX (Monkeypox) viral infection, a zoonotic disease previously confined to the African sub-continent, has caught attention worldwide recently due to its resurgence in a new ‘avatar’ among urban communities. Dermatologists in the U. A. E. started to see patients with fever and a self-limiting pustular necrotic rash that was negative for all other infectious investigations. Methods We performed a prospective observational multicenter clinical study of the demographics, skin manifestations, and outcomes of patients presenting with necrotic pustular lesions and/or fever. Results 35 cases of PCR confirmed MPOX cases, mostly in the expatriate population, were followed up and found to have high-risk heterosexual contact on an average of 1 week prior to disease onset. We found that they have characteristic annular pustular lesions with necrotic center or “Smoke ring pustules’ in all cases. Lesion tenderness and predilection for the lower abdomen, pubic area, and genitalia were observed. Most cases were systemically stable, with fever lasting for an average of 4 days and elevated CRP levels. Genital lesions were prone to secondary bacterial infections. The disease was severe, with larger annular plaques in one of our patients found to be living with HIV. Conclusions The overall prognosis in healthy individuals is good, with lesions healing within an average of 2 weeks without scarring. ‘New world MPOX’ should be unclassified from zoonosis to a sexually transmitted infection (STI) capable of transmission in an urban population. Our findings can help in early clinical suspicion and differentiation from other STI’s for primary and secondary health care physicians.
Plasma serotonin precursors and metabolite are correlated with bone mineral density and bone turnover markers in patients with postmenopausal osteoporosis
Authors: Feng Qinying , Song Xiaoyu , Liu Li , Zhou Xinzhong , Chen Zhihao 
Published: April 2024

Background Serotonin (5-HT) precursors regulate bone remodeling. This study aims to investigate the correlation of plasma 5-HT precursors and metabolite with bone mineral density (BMD) and bone turnover markers in postmenopausal osteoporosis (PMOP) patients. Methods The age, body mass index (BMI), and years since menopause (YSM) were documented for 348 postmenopausal women in normal/osteopenia/osteoporosis (OP) groups, with lumbar spine and femoral neck BMD measured. Serum bone turnover markers (PINP/β-CTX) and plasma 5-HT, 5-HT precursors (Trp/5-HTP) and metabolite (5-HIAA) were measured by ELISA. OP patients were allocated to high/low expression groups following ROC analysis of 5-HT/Trp/5-HTP/5-HIAA. The relationship of plasma 5-HT/Trp/5-HTP/5-HIAA, BMD, and bone turnover markers with PMOP was analyzed using logistic regression analysis. The correlation of plasma 5-HT/Trp/5-HTP/5-HIAA with BMD and bone turnover markers was analyzed using Pearson’s correlation analysis, followed by logistic regression analysis of the relationship between plasma 5-HT/Trp/5-HTP/5-HIAA and BMD, bone turnover markers and PMOP. Results BMI, YSM, BMD and PINP, and β-CTX levels differed among groups. Levels of plasma 5-HT precursors/metabolite were increased in OP patients. Individuals with high 5-HT precursors/metabolite levels had low BMD and high PINP/β-CTX levels. The 5-HT precursors/metabolite negatively-correlated with BMD and positively-correlated with PINP/β-CTX. BMI, YSM, BMD, and PINP/β-CTX/Trp/5-HTP/5-HT related to PMOP and were independent risk factors for OP. Conclusion Plasma 5-HT precursors and metabolite negatively-correlate with BMD and positively-correlate with PINP/β-CTX in PMOP patients. Peripheral 5-HT precursors and metabolite level may be a new direction of treatment of PMOP and bone metabolism-related disorders.
Real-world treatment outcomes from nationwide Onco-colon Turkey registry in RAS wild-type patients treated with biologics second-line mCRC
Authors: Yildirim Mahmut Emre , Karadurmuş Nuri , Ökten İlker Nihat , Türk Hacı Mehmet , Urakçı Zuhat , Arslan Çağatay , Çelik Sinemis , Dane Faysal , Şendur Mehmet Ali Nahit , Bilir Cemil , Karabulut Bülent , Cicin İrfan , Çubukçu Erdem , Karaca Mustafa , Ozcelik Melike , Artaç Mehmet , Tanrikulu Eda , Alacacioglu Ahmet , Açıkgöz Özgür , Öven Başak , Geredeli Çağlayan , Çil Timucin , Harputluoğlu Hakan , Kefeli Umut , Bozkurt Oktay , Tural Deniz , Sakin Abdullah , Yalçın Şuayip , Gumus Mahmut 
Published: April 2024

Backgrounds and Objectives Colorectal cancer is one of the leading causes of mortality both globally and in our country. In Turkey, we conducted a multicenter investigation into the effectiveness of second-line treatments and real-life data for patients with RAS wild-type metastatic colorectal cancer (NCT04757311). Materials and Methods In this retrospective analysis, records from 28 centers were collected, and histopathological, molecular, and clinical characteristics were documented. Patients were categorized into groups based on their second-line biological treatments: anti-EGFR (Group A and Group B, panitumumab and cetuximab) and anti-VEGF (Group C, bevacizumab and aflibercept). They were then compared within these groups. Results A total of 588 patients with documented RAS wild-type status were evaluated. The median OS was 15.7, 14.3 and 14.7 months in Group A, Group B and Group C, respectively ( p  =  0.764). The median PFS of the patients in second-line setting that received panitumumab, cetuximab and bevacizumab/aflibercept were 7.8, 6.6 and 7.4 months, respectively ( p  =  0.848). Conclusion According to the results of our real-life data study, there is no significant difference in efficiency between the combination of biological agent and chemotherapy used in the second-line treatments.