bluuebunny/crossref_metadata_2025_split huggingface dataset:
A brief account of the antibiotics and antibiotic resistance genes in an aquatic environment
Authors: Yadav Nikita , Mandpe Ashootosh , Shukla Sudeep 
Published: April 2024

Abstract
Inappropriate disposal of pharmaceutical waste containing antibiotics into water bodies developed the catastrophe of antibiotic resistance. The occurrence and, thereafter, bioaccumulation of antibiotics in the aquatic ecosystem have raised concern about their associated toxicity toward aquatic organisms. Their presence in aquatic bodies has been widely discussed in developed nations. However, in many developing countries like India, minimal research has been reported on the status of antibiotics in the aquatic environment. This chapter summarizes the global distribution of antibiotics in the aquatic environment, their effects on the microbial community, the evaluation and assessment of antibiotic risks, and the source tracking of these emerging pollutants. Another key objective of this chapter is to investigate the trends in consumption, distribution, and fate of major antibiotic classes in India and their dynamic relation to the biotic world. The eco-toxicity of these emerging contaminants towards different flora and fauna communities at different trophic levels with targeted assessment and remediation technologies, including percent removal efficiencies, has been discussed. Legislative and regulatory measures carried out for the effective management of this growing epidemic by various governments have also been discussed.
A novel machine learning-based framework for the water quality parameters prediction using hybrid long short-term memory and locally weighted scatterplot smoothing methods
Authors: Dodig Ana , Ricci Elisa , Kvascev Goran , Stojkovic Milan 
Published: April 2024

ABSTRACT

Water quality prediction is crucial for effective river stream management. Dissolved oxygen, conductivity and chemical oxygen demand are vital chemical parameters for water quality. Development of machine learning (ML) and deep learning (DL) methods made them widely used in this domain. Sophisticated DL techniques, especially long short-term memory (LSTM) networks, are required for accurate, real-time multistep prediction. LSTM networks are effective in predicting water quality due to their ability to handle long-term dependencies in sequential data. We propose a novel hybrid approach for water quality parameters prediction combining DL with data smoothing method. The Sava river at the Jamena hydrological station serves as a case study. Our workflow uses LSTM networks alongside LOcally WEighted Scatterplot Smoothing (LOWESS) technique for data filtering. For comparison, Support Vector Regressor (SVR) is used as the baseline method. Performance is evaluated using Root Mean Squared Error (RMSE) and Coefficient of Determination R2 metrics. Results demonstrate that LSTM outperforms the baseline method, with an R2 up to 0.9998 and RMSE of 0.0230 on the test set for dissolved oxygen. Over a 5-day prediction period, our approach achieves R2 of 0.9912 and RMSE of 0.1610 confirming it as a reliable method for water quality multistep parameters prediction.
A leader must take charge of everything
Authors: Meshalkin E. 
Published: April 2024

An interview with Evgeny N. Meshalkin “A leader must take charge of everything” was published in the first Patologiya krovoobrashcheniya i kardiokhirurgiya issue in 1997 (Patologiya krovoobrashcheniya i kardiokhirurgiya;1997(1):14-16). The paper has been reproduced exactly as it originally appeared.
Research on the Path of High-Quality Development of Internal Audit in Real Estate Industry
Authors: Lv Baofeng 
Published: April 2024

The internal audit of real estate enterprises is a very important part of the business activities of enterprises, is an important means to effectively control the internal management risk of enterprises, improve the efficiency of operation and management, and reduce costs. High-quality internal audit plays a very important role in the development and growth of enterprises. Based on the present situation of the internal audit of real estate industry, this paper analyzes the problems existing in the internal audit of real estate enterprises, and puts forward the corresponding improvement measures.
Enhancing the ETAS model: incorporating rate-dependent incompleteness, constructing a representative dataset, and reducing bias in inversions
Authors: Kamranzad Farnaz , Naylor Mark , Lindgren Finn , Bayliss Kirsty , Main Ian 
Published: April 2024

The development of reliable operational earthquake forecasts is
dependent upon managing uncertainty and bias in the parameter
estimations obtained from models like the Epidemic-Type Aftershock
Sequence (ETAS) model. Given the intrinsic complexity of the ETAS model,
this paper is motivated by the questions: “What constitutes a
representative sample for fitting the ETAS model?” and “What biases
should we be aware of during survey design?”. In this regard, our
primary focus is on enhancing the ETAS model’s performance when dealing
with short-term temporally transient incompleteness, a common phenomenon
observed within early aftershock sequences due to waveform overlaps
following significant earthquakes. We introduce a methodological
modification to the inversion algorithm of the ETAS model, enabling the
model to effectively operate on incomplete data and produce accurate
estimates of the ETAS parameters. We build on a Bayesian approach known
as inlabru, which is based on the Integrated Nested Laplace
Approximation (INLA) method. This approach provides posterior
distributions of model parameters instead of point estimates, thereby
incorporating uncertainties. Through a series of synthetic experiments,
we compare the performance of our modified version of the ETAS model
with the original (standard) version when applied to incomplete
datasets. We demonstrate that the modified ETAS model effectively
retrieves posterior distributions across a wide range of mainshock
magnitudes and can adapt to various forms of data incompleteness,
whereas the original model exhibits bias. In order to put the scale of
bias into context, we compare and contrast further biases arising from
different scenarios using simulated datasets. We consider: (1)
sensitivity analysis of the modified ETAS model to a time binning
strategy; (2) the impact of including and conditioning on the historic
run-in period; (3) the impact of combination of magnitudes and trade-off
between the two productivity parameters K
and α; and (4) the sensitivity to incompleteness
parameter choices. Finally, we explore the utility of our modified
approach on three real earthquake sequences including the 2016 Amatrice
earthquake in Italy, the 2017 Kermanshah earthquake in Iran, and the
2019 Ridgecrest earthquake in the US. The outcomes suggest a significant
reduction in biases, underlining a marked improvement in parameter
estimation accuracy for the modified ETAS model, substantiating its
potential as a robust tool in seismicity analysis.
Chronology of sedimentation and landscape evolution in the Okavango Rift Zone, a developing young rift in southern Africa
Authors: Vainer Shlomy , Vainer S , Schmidt C , Garzanti E , Dor Y Ben , Pastore G , Mokatse T , Prud'homme C , Leanni L , King G , Team Aster , Verrecchia E P , Aumaître Georges , Bourlès Didier L , Keddadouche Karim 
Published: April 2024

The Kalahari Basin in southern Africa, shaped by subsidence and
epeirogeny, features the Okavango Rift Zone (ORZ) as a significant
structural element characterized by diffused extensional deformation
forming a prominent depocenter. This study elucidates the Pleistocene
landscape evolution of the ORZ by examining the chronology of sediment
formation and filling this incipient rift and its surroundings.
Modeling of cosmogenic nuclide concentrations in surficial eolian sand
from distinct structural blocks around the ORZ provides insights into
sand’s residence time on the surface. Sand formation occurred from
~2.2 to 1.1 Ma, coinciding with regional tectonic
events. Notably, provenance analyses of sand within ORZ’s lowermost
block where large alluvial fans are found indicate different source
rocks and depositional environments than those of the eolian sands found
at a higher elevation. This suggests that the major phase of rift
subsidence and the following incision of alluvial systems into the rift
occurred after eolian dune formation. Luminescence dating reveals that
deposition in alluvial fan settings in the incised landscape began not
later than ~250 ka, and that a lacustrine environment
existed since at least ~140 ka.
The established chronological framework constrains the geomorphological
effects of the different tectono-climatic forces that shaped this
nascent rifting area. It highlights two pronounced stages of landscape
development, with the most recent major deformation event in the
evolving rift probably occurring during the middle Pleistocene
transition (1.2-0.75 Ma). This event is reflected as a striking change
in the depositional environments due to the configurational changes
accompanying rift progression.
Unethical Peer Review
Authors: Sangster Alan 
Published: April 2024

ABSTRACT
This paper calls for greater ethical standards in the peer review process. Critical analysis through the lens of the COPE Ethical Guidelines for Peer Reviewers is performed on two reviews received on different versions of a paper from two different journals. Both are relentlessly negative. Neither is executed ethically. No justifiable significant criticism is evident. Both appear influenced by confirmation bias. One is characterized by apparent misreading of both the paper and the reviewer’s sources, plus failure to check criticism was valid. The rhetorical style of the other diminishes clarity, introduces ambiguity, and bewilders. It conveys overwhelming negativity with no supporting substance. This paper is the first to contribute to this theme in both the accounting and the accounting history literature. It is hoped it will encourage reviewers to be ethical, that it results in unethical reviews being more readily detected, and authors being better equipped to address reviewer comments.
Surgical approach and presence of preoperative pleural effusion impact thoracostomy tube usage in dogs and cats following thoracic surgery for suspected neoplasia
Authors: Johnson Carley , Lapsley Janis , Piegols Hunter , Selmic Laura 
Published: April 2024

Abstract

OBJECTIVE
To assess factors associated with increased pleural fluid and air evacuation, longer duration of thoracostomy tube usage, and longer hospitalization in dogs and cats following surgery for thoracic neoplasms.

ANIMALS
62 dogs and 10 cats.

METHODS
Medical records were reviewed for dogs and cats undergoing thoracic surgeries between August 1, 2019, and June 30, 2023, for resection of suspected neoplasia in which a thoracostomy tube was placed. Data collected included patient signalment, type of procedure performed, histologic diagnosis of the primary mass removed, volume of fluid and air evacuated from the thoracostomy tube, and time in hospital.

RESULTS
Median sternotomy was associated with increased total fluid evacuation (median, 12.1 mL/kg; IQR, 15.4 mL/kg; P = .012), whereas rib resection was associated with increased total air evacuation (median, 2.1 mL/kg; IQR, 13.6 mL/kg; P = .06). The presence of preoperative pleural effusion was associated with higher total fluid evacuation (20.6 mL/kg; IQR, 32.1 mL/kg; P = .009), longer duration with a thoracostomy tube in place (42.5 hours; IQR, 41.9 hours; P = .027), and longer hospitalization period (61 hours; IQR, 52.8 hours; P = .025). Cats had a thoracostomy tube in place for a longer time compared to dogs (median, 42.6 hours; IQR, 23.5 hours; P = .043).

CLINICAL RELEVANCE
Animals undergoing median sternotomy and rib resection may be expected to have higher fluid and air volumes, respectively, evacuated postoperatively. This often leads to an increased duration of thoracostomy tube usage and a longer period of hospitalization.
Methylenetetrahydrofolate reductase levels and gene expression in leukemia
Authors: Thabit Jinan , Jasib Anwar , Irhaeem Mudad , Al Rufaie Mohauman Mohammed 
Published: April 2024

Abstract
Leukemia is a neoplastic disease that affects the proliferation of white blood cells and their progenitors. Folic acid deficiency is well-known as a risk factor for leukemia. Methylenetetrahydrofolate reductase (MTHFR) enzyme functions in the folate metabolism route, DNA synthesis and methylation processes. Numerous research has been conducted to investigate the link between MTHFR and several human illnesses, including cancer, cardiovascular disease, psychiatric disorders and neurological issues. The current study aimed to examine MTHFR levels and gene expression in patients with leukemia. The research was carried out between February and October of 2022. There were 130 subjects in total, 80 with leukemia, 45 with AML (Female = 16, Male = 26) with a mean age of (32.32±2.69), and 35 with ALL (Female = 16, Male = 19) with a mean age of (35.794±0.63). The study included 50 healthy subjects as a healthy control group (Female = 28, Male = 22), with an average age of (41.8±1.57) years. MTHFR and Folic acid were measured using ELISA, while MTHFR mRNA was assessed using qPCR in blood and plasma. Folic acid and MTHFR levels were found to be lower in patients with AML and ALL compared to controls (p <0.01). MTHFR gene expression was found to be downregulated in leukemia patients (p <0.01).
The findings of the study give support for future research into the effect of folic acid level and supplementation on leukemia-associated pathological outcomes. Folic acid deficiency may affect the folate mediate-one carbon metabolism pathway, as evidenced by changes in the expression of the mRNA MTHFR gene. As a result, more research into the effects of folate status and folic acid supplementation on leukemia is needed to investigate potential therapeutic strategies.
Pandemic Pressures: A Study on the Forms of Violence Against Students During Online Learning
Authors: Supraja Muhamad 
Published: April 2024

Abstract
This research aims to find out and analyze three forms of violence experienced by primary education students during the COVID-19 pandemic, namely domestic violence, violence due to the use of technology (gadgets, the internet), and violence committed by schools or teachers against students. In this research, the researcher did not find domestic violence committed by mothers against their children who were conducting online learning during the Covid-19 Pandemic, except found that the potential for violence still exists, so that at any time, it can be manifested if mothers fail to manage the socioeconomic pressures they face. The researcher of this study also sees the critical role of technology in online learning during the Pandemic. However, technology has also given birth to violence in its form, starting from internet access that is not easily accessible to every student, the uneven distribution of the internet network, as well the increasing number of tasks and learning loads charged to students, also the necessity for students to look for learning materials through various existing internet sources, and the demand to submit schoolwork or those that must be equipped with video images and audio (voice). During the COVID-19 pandemic, schools also failed to implement democratic learning pedagogy because schools only highlight aspects of academic learning, forgetting the importance of accommodating children’s rights in interacting and playing with others (social), so many students felt bored, saturated, and depressed.
Challenging Sanctions: What Price Is Belarus Willing to Pay to Maintain the Autocratic Regime?
Authors: Ahmed Saeed 
Published: April 2024

Abstract
Since the fall of the Soviet Union in 1991 and state building process for Belarusian newly formed government till the elections held in August 2020, ensuring the continuity of one of the last autocracies in the world, circumstances have altered cases. It is the kind of challenge the European Union never expected to deal with, especially following the Minsk signing of the Memorandum of Understanding to create the OSCE-led Advisory Monitory Group in 1997. This paper will examine and explore the different stages in the rise of a repressive regime, the buffering role that Belarus plays in the stage of sanctions, as well as the economic implications that a partnership between the EU and Belarus might have had in the case of a successful OSCE mission and European External Action Services (EEAS) to six Eastern Europe States, including Belarus. The potential outcomes would indicate improved quality of life, more business opportunities, liberalization of economic activity and financial assistance.
Online Impression Management on Linkedin: Phenomenological Study Among Indonesian Fresh Graduates
Authors: Fadhila Sarah Annisa , Sukmayadi Vidi , Affandi Ahmad Fahrul Muchtar 
Published: April 2024

Objective: This study aims to explore the experiences of recent graduates using LinkedIn, a social media platform, to find and secure employment after completing their studies.

Theoretical Framework: The authors explore the lived experiences of successful LinkedIn users through the lens of phenomenology. The authors also draw on Impression Management Theory (IMT) to understand how the users display themselves on LinkedIn by utilizing the platform's available features to accomplish their desired outcomes.

Method: This study was organized using a qualitative approach with phenomenological methods. Data were collected by interviewing ten recent graduates who use LinkedIn. The interview data were analyzed by bracketing, finding key statements, identifying codes and grouping themes, and constructing textural descriptions.

Result and Discussion: The findings indicate that fresh graduates view LinkedIn as a platform to enhance their personal branding. One of the most significant strategies is to make their LinkedIn profile as professional as possible—despite their lack of work experience.

Research Implications: Career development professionals and educators could use this study's findings to understand better how fresh graduates use LinkedIn for impression management and can assist them in making the most of social media for their career management.

Originality/Value: The study presents practical implications within the social context of Indonesia that have yet to be thoroughly examined in prior studies. Specifically, it can provide guidance for fresh graduates on optimizing their LinkedIn accounts by drawing on the experiences of the country's successful LinkedIn users.
The Existence of Law no. 5 of 1960 on the Governor's Instructions DIY No: K.898/I/A/75 Ownership of Land Rights by Chinese Writers Viewed from Justice Perspective
Authors: Nachrawi Gunawan 
Published: April 2024

Purpose: This study aims to examine the implications of DIY Regional Head Instruction No.K.898/I/A/75 on land ownership rights, particularly for Indonesian citizens of Chinese descent, in the context of existing legal frameworks and constitutional principles.

Theoretical reference: The study draws on legal theories concerning land ownership rights, including the Indonesian Agrarian Law (UUPA), Law No. 5 of 1960, and constitutional principles related to property rights and equality before the law.

Method: A qualitative analysis of legal documents, including statutes, regulations, and constitutional provisions, is conducted to explore the legal basis and implications of DIY Regional Head Instruction No.K.898/I/A/75 on land ownership rights.

Results and Conclusion: The study finds that the enactment of DIY Regional Head Instruction No.K.898/I/A/75 presents a contradiction with existing legal frameworks, particularly the UUPA and Law No. 5 of 1960, regarding land ownership rights. Despite being an instruction limited to the DIY region, its impact on land rights allocation is significant, leading to challenges, particularly for Indonesian citizens of Chinese descent. The study concludes that the instruction should be repealed to ensure equality and adherence to constitutional principles regarding property rights.

Implications of research: This research highlights the need for legal clarity and consistency in land ownership regulations, especially concerning the rights of minority groups such as Indonesian citizens of Chinese descent. Addressing inconsistencies and ensuring adherence to constitutional principles will contribute to promoting fairness and justice in land ownership rights allocation.
Medically responsive amyloidogenic giant sellar-parasellar prolactinoma
Authors: Singh Anoop Kumar , Shilpi  , Kumari Gayatri , Tangri Rajiv 
Published: April 2024

Background:
Giant prolactinomas are rare; among them, the amyloidogenic variant, prolactinomas with extensive spherical amyloid deposits, are rare, with only 30 cases reported with recommendations of surgical management contrary to the routine prolactinoma’s medical management.

Case Description:
We report here a case of giant amyloidogenic prolactinoma in a 32-year-old male patient who had a very atypical presentation in terms of clinical, radiological, and pathological features and responded to dopamine agonist therapy like a normal prolactinoma.

Conclusion:
Amyloidogenic giant prolactinomas are rare. Contrary to usual belief, even they remain medically responsive; however, more literature is required to decide their ideal management.
Emergence of OXA-48-like producing Citrobacter species, Germany, 2011 to 2022
Authors: Sommer Julian , Reiter Hannah , Sattler Janko , Cacace Elisabetta , Eisfeld Jessica , Gatermann Sören , Hamprecht Axel , Göttig Stephan 
Published: April 2024

Background
Carbapenemase-producing Enterobacterales are a public health threat worldwide and OXA-48 is the most prevalent carbapenemase in Germany and western Europe. However, the molecular epidemiology of OXA-48 in species other than Escherichia coli and Klebsiella pneumoniae remains poorly understood.

Aim
To analyse the molecular epidemiology of OXA-48 and OXA-48-like carbapenemases in Citrobacter species (spp.) in Germany between 2011 and 2022.

Methods
Data of 26,822 Enterobacterales isolates sent to the National Reference Centre (NRC) for Gram-negative bacteria were evaluated. Ninety-one Citrobacter isolates from 40 German hospitals harbouring bla
OXA-48/OXA-48‑like were analysed by whole genome sequencing and conjugation experiments.

Results
The frequency of OXA-48 in Citrobacter freundii (CF) has increased steadily since 2011 and is now the most prevalent carbapenemase in this species in Germany. Among 91 in-depth analysed Citrobacter spp. isolates, CF (n = 73) and C. koseri (n = 8) were the most common species and OXA-48 was the most common variant (n = 77), followed by OXA-162 (n = 11) and OXA‑181 (n = 3). Forty percent of the isolates belonged to only two sequence types (ST19 and ST22), while most other STs were singletons. The plasmids harbouring bla
OXA‑48 and bla
OXA-162 belonged to the plasmid types IncL (n = 85) or IncF (n = 3), and plasmids harbouring bla
OXA‑181 to IncX3 (n = 3). Three IncL plasmid clusters (57/85 IncL plasmids) were identified, which were highly transferable in contrast to sporadic plasmids.

Conclusion
In CF in Germany, OXA-48 is the predominant carbapenemase. Dissemination is likely due to distinct highly transmissible plasmids harbouring bla
OXA‑48 or bla
OXA-48-like and the spread of the high-risk clonal lineages ST19 and ST22.