bluuebunny/crossref_metadata_2025_split huggingface dataset:
Percutaneous ultrasonographically guided radiofrequency heat ablation for treatment of primary hyperparathyroidism in dogs
Authors: Pollard Rachel E. , Long Craig D. , Nelson Richard W. , Hornof William J. , Feldman Edward C. 
Published: July 2006

AbstractObjective—To evaluate the efficacy and safety of ultrasonographically guided radiofrequency heat ablation of parathyroid masses in dogs with primary hyperparathyroidism.Design—Clinical trial.Animals—11 dogs.Procedure—In all dogs, either 1 or 2 parathyroid masses were evident ultrasonographically. Dogs were anesthetized, and a 20-gauge over-the-needle catheter was directed into the parathyroid mass via ultrasonographic guidance. Radiofrequency heat was applied to the stylet of the catheter until there was sonographically apparent change to the entire parenchyma of the mass. Serum total and ionized calcium and parathyroid hormone concentrations were monitored daily for 5 days after the ablation procedure and again at 1, 2, and 3-month intervals, if possible. Dogs were monitored for adverse effects.Results—One treatment was required in 6 dogs, 2 treatments were required in 2 dogs, and treatment was unsuccessful in 3 dogs. Serum total and ionized calcium concentrations were within reference ranges within 2 days of the last procedure in all 8 successfully treated dogs. Serum parathyroid hormone concentration was decreased 24 hours after treatment in all 8 dogs. Hypocalcemia developed in 5 of the 8 successfully treated dogs, all of which required treatment. One dog had a transient voice change. Other adverse effects were not reported.Conclusions and Clinical Relevance—Ultrasonographically guided radiofrequency heat ablation of parathyroid masses is a safe and effective alternative to surgery in dogs with primary hyperparathyroidism. (J Am Vet Med Assoc2001;218:1106–1110)
Epidemiology of feline infectious peritonitis among cats examined at veterinary medical teaching hospitals
Authors: Rohrbach Barton W. , Legendre Alfred M. , Baldwin Charles A. , Lein Donald H. , Reed Willie M. , Wilson Ronald B. 
Published: July 2006

AbstractObjective—To determine proportions of cats in which feline infectious peritonitis (FIP) was diagnosed on an annual, monthly, and regional basis and identify unique characteristics of cats with FIP.Design—Case-control study.Sample Population—Records of all feline accessions to veterinary medical teaching hospitals (VMTH) recorded in the Veterinary Medical Data Base between January 1986 and December 1995 and of all feline accessions for necropsy or histologic examination at 4 veterinary diagnostic laboratories.Procedure—Proportions of total and new feline accessions for which a diagnosis of FIP was recorded were calculated. To identify characteristics of cats with FIP, cats with FIP were compared with the next cat examined at the same institution (control cats).Results—Approximately 1 of every 200 new feline and 1 of every 300 total feline accessions at VMTH in North America and approximately 1 of every 100 accessions at the diagnostic laboratories represented cats with FIP. Cats with FIP were significantly more likely to be young, purebred, and sexually intact males and significantly less likely to be spayed females and discharged alive than were control cats. The proportion of new accessions for which a diagnosis of FIP was recorded did not vary significantly among years, months, or regions of the country.Conclusions and Clinical Relevance—Results indicated that FIP continues to be a clinically important disease in North America and that sexually intact male cats may be at increased risk, and spayed females at reduced risk, for FIP. The high prevalence of FIP and lack of effective treatment emphasizes the importance of preventive programs, especially in catteries. (J Am Vet Med Assoc2001;218:1111–1115)
Susceptibility of cattle to infection with Ehrlichia equi and the agent of human granulocytic ehrlichiosis
Authors: Pusterla Nicola , Anderson Randall J. , House John K. , Berger Pusterla Jeannine , DeRock Elfriede , Madigan John E. 
Published: July 2006

AbstractObjective—To determine susceptibility of cattle to infection withEhrlichia equiand the agent of human granulocytic ehrlichiosis (HGE).Design—Experimental disease and prevalence survey.Animals—6 cattle, 2 horses, and 2,725 serum samples from healthy cattle.Procedure—2 cattle and 1 horse were inoculated withE equi, 2 cattle and 1 horse were inoculated with the HGE agent, and 2 cattle served as sham-inoculated controls; inoculated animals were evaluated via clinical, hematologic, serologic, and real-time polymerase chain reaction tests. Prevalence of antibodies againstE equiin 2,725 healthy cattle was determined by use of an indirect immunofluorescent technique.Results—No abnormal clinical or hematologic findings or inclusion bodies within granulocytes were observed in the cattle after inoculation, and results of all polymerase chain reaction tests were negative. Seroconversion in inoculated cattle developed 10 to 12 days after inoculation (reciprocal titers, 160). Both horses developed clinical signs of ehrlichiosis. Five of 2,725 (0.18%) cattle were seropositive forE equi, with titers ranging from 20 to 80. All seropositive cattle originated from the same tick-rich region in the Sierra Nevada foothills.Conclusions and Clinical Relevance—Results suggest that cattle are not susceptible to infection withE equior the agent of HGE and that prevalence of exposure toE equiin healthy cattle is low. Therefore,E equiand the agent of HGE are likely of negligible importance for cattle in North America. (J Am Vet Med Assoc2001;218:1160–1162)
Evaluation of a commercial ELISA for diagnosis of paratuberculosis in cattle
Authors: Dargatz David A. , Byrum Beverly A. , Barber Linda K. , Sweeney Raymond W. , Whitlock Robert H. , Shulaw William P. , Jacobson Richard H. , Stabel Judith R. 
Published: July 2006

AbstractObjective—To evaluate sensitivity and specificity of a new ELISA for antibodies againstMycobacterium aviumsubspparatuberculosis.Design—Cross-sectional observational survey.Sample Population—Serum samples from 590 cattle that were infected withM aviumsubspparatuberculosisand 723 cattle that were not infected.Procedure—Serum samples were tested by use of an ELISA for antibodies againstM aviumsubspparatuberculosis.Results—Sensitivity of the test varied from 15.4 to 88.1%, depending on the clinical stage and bacterial shedding status of the cattle.Conclusions and Clinical Relevance—Results obtained with use of the new ELISA agreed favorably with those of a previous ELISA. Practitioners must be aware of variability in the sensitivity of the test, which depends on the clinical and shedding status of the cattle, because this may affect interpretation of test results. (J Am Vet Med Assoc2001;218:1163–1166)
Results of magnetic resonance imaging in dogs with vestibular disorders: 85 cases (1996–1999)
Authors: Garosi Laurent S. , Dennis Ruth , Penderis Jacques , Lamb Christopher R. , Targett Mike P. , Cappello Rodolfo , Delauche Agnes J. 
Published: July 2006

Abstract

Objective—To determine results of magnetic resonance
(MR) imaging in dogs with vestibular disorders
(VD) and correlate results of MR imaging with clinical
findings.

Design—Retrospective study.

Animals—85 dogs.

Procedure—Information on signalment, clinical signs,
and presumptive lesion location was obtained from
the medical records, and MR images were reviewed.

Results—27 dogs had peripheral VD, 37 had central VD,
and 21 had paradoxical VD. Of the 27 dogs with peripheral
VD, 11 (41%) had MR imaging abnormalities involving
the ipsilateral tympanic bulla compatible with otitis
media (6 also had abnormalities involving the petrous
portion of the ipsilateral temporal bone compatible with
otitis interna), 7 (26%) had MR imaging abnormalities
compatible with middle ear neoplasia, 2 (7%) had an ipsilateral
cerebellopontine angle lesion, and 7 (26%) did not
have MR imaging abnormalities. All dogs with central
and paradoxical VD had abnormalities evident on MR
images. Of the 37 dogs with central VD, 13 (35%) had an
extra-axial lesion, 6 (16%) had an intra-axial lesion, and
18 (49%) had multiple intra-axial lesions. In 23 (62%)
dogs with central VD, lesions on MR images corresponded
with location suspected on the basis of clinical
signs. Of the 21 dogs with paradoxical VD, 12 (57%) had
an extra-axial lesion, 5 (24%) had an intra-axial lesion,
and 4 (19%) had multiple intra-axial lesions. Location of
lesions on MR images agreed with location suspected
on the basis of clinical signs in 19 (90%) dogs.

Conclusions and Clinical Relevance—Results suggest
that MR imaging may be helpful in the diagnosis
and treatment of VD in dogs. (J Am Vet Med Assoc
2001;218:385–391)
Intraocular pressure measurements obtained as part of a comprehensive geriatric health examination from cats seven years of age or older
Authors: Kroll Mandy M. , Miller Paul E. , Rodan Ilona 
Published: July 2006

AbstractObjective—To determine intraocular pressure (IOP) in cats ≥ 7 years of age undergoing a routine comprehensive geriatric health examination.Design—Prospective study.Animals—538 cats (1,068 eyes).Procedure—IOP was measured by applanation tonometry following instillation of 0.5% proparacaine.Results—Mean ± SD IOP for all eyes was 12.3 ± 4.0 mm Hg (range, 4 to 31 mm Hg). Mean age was 12.3 ± 2.9 years. Intraocular pressure did not vary significantly cross-sectionally with age. However, in 78 cats, IOP was measured more than once, and follow-up measurements were significantly less than initial measurements (mean time between measurements, 9.4 ± 3.0 months). The most useful tonometric criteria for identifying ocular abnormalities on the basis of IOP was an IOP ≥ 25 mm Hg (mean + 3 SD) or a difference in IOP between eyes ≥ 12 mm Hg. Eight cats met these criteria, and 5 of these cats had ophthalmic abnormalities. Low IOP was a nonspecific indicator of the presence of ocular abnormalities, as 111 cats had an IOP ≤ 8 mm Hg, but only 2 had uveitis.Conclusions and Clinical Relevance—Results suggest that IOP measurements can be a useful addition to a comprehensive geriatric health examination in cats ≥ 7 years of age, especially when combined with an ophthalmic examination. Cats without ocular abnormalities that have IOP ≥ 25 mm Hg or a ≥ 12 mm Hg difference in IOP between eyes should have tonometry repeated or be referred to an ophthalmologist for further evaluation before beginning antiglaucoma treatment. (J Am Vet Med Assoc2001;219: 1406–1410)
Efficacy of a nonantimicrobial cream administered topically for treatment of digital dermatitis in dairy cattle
Authors: Moore Dale A. , Berry Steven L. , Truscott Marla L. , Koziy Vasyl 
Published: July 2006

AbstractObjective—To compare efficacy of a topically administered nonantimicrobial cream with that of lincomycin for treatment of digital dermatitis in dairy cattle.Design—Randomized clinical trial.Animals—98 cows from a commercial Holstein dairy herd.Procedure—Cows with active lesions of digital dermatitis identified on a single observation day were randomly assigned to receive a nonantimicrobial cream, lincomycin paste, or no treatment. Cows were examined approximately every 4 weeks for 130 days after treatment for lesion maturity score, score for signs of pain, lesion size, and lesion activity.Results—29 days after a single treatment, both treated groups had significantly reduced scores for signs of pain, lesion activity, lesion size, and the decision to retreat, compared with findings in the untreated group. Efficacy of the 2 treatments was not significantly different for decreasing pain score or lesion activity or for increasing lesion maturity score, but lincomycin was significantly more efficacious in decreasing lesion size and avoiding retreatment. By use of multivariate logistic regression, lactation number was a significant treatment effect modifier on the outcome of a healed lesion after treatment. Cows with ≥ 3 lactations were more likely to have a healed lesion at 29 days, compared with first- and secondlactation cows.Conclusions and Clinical Relevance—Because antimicrobial treatments for digital dermatitis in cows require a veterinarian's prescription, the nonantimicrobial cream could serve as a viable but less consistently effective alternative to antimicrobials and could be applied by veterinarians, hoof trimmers, and others. (J Am Vet Med Assoc2001;219:1435–1438)
Results of ambulatory electrocardiography in overtly healthy Doberman Pinschers with equivocal echocardiographic evidence of dilated cardiomyopathy
Authors: Calvert Clay A. , Wall Michelle 
Published: July 2006

AbstractObjective—To determine results of ambulatory electrocardiography in and outcome of overtly healthy Doberman Pinschers with equivocal echocardiographic evidence of dilated cardiomyopathy.Design—Case series.Animals—44 overtly healthy (25 male, 19 female) Doberman Pinschers.Procedure—24-hour ambulatory electrocardiographic (Holter) recordings with > 90% scan quality obtained the same day that echocardiography was performed were reviewed.Results—Holter recordings from 42 of 44 (95%) dogs contained ventricular premature complexes (VPC). Fifteen of 44 (34%) dogs had > 100 VPC, 9 (20%) had > 500 VPC, and 5 (11%) had > 1,000 VPC. Nonsustained (< 30 seconds) ventricular tachycardia was detected in 4 dogs. Eighteen of 27 (67%) dogs with > 100 VPC, any couplets or triplets of VPC, or ventricular tachycardia developed dilated cardiomyopathy within 1 year, compared with 8 of 17 (47%) dogs with < 100 VPC, no couplets or triplets of VPC, and no ventricular tachycardia. Of the 18 dogs that did not develop dilated cardiomyopathy within 1 year, 11 (61%) did so within 3 years.Conclusions and Clinical Relevance—Results suggest that a high percentage of Doberman Pinschers with equivocal echocardiographic evidence of dilated cardiomyopathy will be found to have VPC during 24-hour ambulatory electrocardiography and that most will develop echocardiographic abnormalities indicative of cardiomyopathy. (J Am Vet Med Assoc2001;219:782–784)
Effects of a program of human interaction and alterations in diet composition on activity of the hypothalamic-pituitary-adrenal axis in dogs housed in a public animal shelter
Authors: Hennessy Michael B. , Voith Victoria L. , Hawke Jesse L. , Young Travis L. , Centrone Jason , McDowell Angela L. , Linden Fran , Davenport Gary M. 
Published: July 2006

AbstractObjective—To determine whether a program of human interaction or alterations in diet composition would alter activity of the hypothalamic-pituitaryadrenal (HPA) axis in dogs housed in an animal shelter.Design—Prospective study.Animals—40 dogs.Procedure—Dogs were (n = 20) or were not (20) enrolled in a program of regular supplemental human interaction (20 min/d, 5 d/wk, for 8 weeks) involving stroking, massaging, and behavioral training. In addition, half the dogs in each group were fed a typical maintenance-type diet, and the other half were fed a premium diet. Plasma cortisol and ACTH concentrations were measured during weeks 0, 2, 4, and 8 and before and after exposure to a battery of novel situations during weeks 0 and 8.Results—Plasma cortisol concentration was significantly decreased by week 2, but plasma ACTH concentration was not significantly decreased until week 8 and then only in dogs fed the premium diet. Following exposure to novel situations, plasma cortisol and ACTH concentrations were significantly increased. However, during week 8, dogs enrolled in the program of human interaction had significantly lower increases in cortisol concentration than did dogs not enrolled in the program.Conclusions and Clinical Relevance—Results suggest that both a program of human interaction and alterations in diet composition have moderating effects on activity of the HPA axis in dogs housed in an animal shelter and that activity of the HPA axis may be increased for a longer period during shelter housing than measurement of plasma cortisol concentration alone would suggest. (J Am Vet Med Assoc2002;221:65–71)
Use of low doses of ketamine administered by constant rate infusion as an adjunct for postoperative analgesia in dogs
Authors: Wagner Ann E. , Walton Judy A. , Hellyer Peter W. , Gaynor James S. , Mama Khursheed R. 
Published: July 2006

AbstractObjective—To compare indicators of postoperative pain and behavior in dogs with and without a lowdose ketamine infusion added to usual perioperative management.Design—Prospective, randomized, blinded clinical study.Animals—27 dogs undergoing forelimb amputation.Procedure—Dogs were anesthetized with glycopyrrolate, morphine, propofol, and isoflurane. Thirteen dogs were treated with ketamine IV, as follows: 0.5 mg/kg (0.23 mg/lb) as a bolus before surgery, 10 µg/kg/min (4.5 µg/lb/min) during surgery, and 2 µg/kg/min (0.9 µg/lb/min) for 18 hours after surgery. Fourteen dogs received the same volume of saline (0.9% NaCl) solution. All dogs received an infusion of fentanyl (1 to 5 µg/kg/h [0.45 to 2.27 µg/lb/h]) for the first 18 hours after surgery. Dogs were evaluated for signs of pain before surgery, at the time of extubation, and 1, 2, 3, 4, 12, and 18 hours after extubation. Owners evaluated their dogs' appetite, activity, and wound soreness on postoperative days 2, 3, and 4.Results—Dogs that received ketamine infusions had significantly lower pain scores 12 and 18 hours after surgery and were significantly more active on postoperative day 3 than dogs that received saline solution infusions.Conclusions and Clinical Relevance—Results suggest that perioperative administration of low doses of ketamine to dogs may augment analgesia and comfort in the postoperative surgical period. (J Am Vet Med Assoc2002;221:72–75)
Clinical features of avian vacuolar myelinopathy in American coots
Authors: Larsen R. Scott , Nutter Felicia B. , Augspurger Tom , Rocke Tonie E. , Tomlinson Lindsay , Thomas Nancy J. , Stoskopf Michael K. 
Published: July 2006

Abstract

Objective—To characterize clinical features of avian
vacuolar myelinopathy (AVM) in American coots.

Design—Case-control study.

Animals—26 AVM-affected American coots and 12
unaffected coots.

Procedures—Complete physical, neurologic, hematologic,
and plasma biochemical evaluations were
performed. Affected coots received supportive care.
All coots died or were euthanatized, and AVM status
was confirmed via histopathologic findings.

Results—3 severely affected coots were euthanatized
immediately after examination. Seventeen
affected coots were found dead within 7 days of
admission, but 5 affected coots survived > 21 days
and had signs of clinical recovery. Abnormal physical
examination findings appeared to be related to general
debilitation. Ataxia (88%), decreased withdrawal
reflexes (88%), proprioceptive deficits (81%),
decreased vent responses (69%), beak or tongue
weakness (42%), and head tremors (31%), as well as
absent pupillary light responses (46%), anisocoria
(15%), apparent blindness (4%), nystagmus (4%),
and strabismus (4%) were detected. Few gross
abnormalities were detected at necropsy, but histologically,
all AVM-affected coots had severe vacuolation
of white matter of the brain. None of the control
coots had vacuolation.

Conclusions and Clinical Relevance—Although
there was considerable variability in form and severity
of clinical neurologic abnormalities, clinical signs
common in AVM-affected birds were identified.
Clinical recovery of some AVM-affected coots can
occur when supportive care is administered. Until the
etiology is identified, caution should be exercised
when rehabilitating and releasing coots thought to be
affected by AVM. (J Am Vet Med Assoc 2002;221:
80–85)
Medical and surgical treatment of pyothorax in dogs: 26 cases (1991–2001)
Authors: Rooney Matthew B. , Monnet Eric 
Published: July 2006

AbstractObjective—To compare outcomes of dogs with pyothorax treated medically versus surgically and to identify prognostic indicators for dogs with pyothorax.Design—Retrospective study.Animals—26 dogs.Procedure—Medical records were reviewed to obtain information regarding signalment, results of physical and laboratory evaluations at the time of initial examination, results of bacterial culture of pleural fluid, radiographic abnormalities, treatment (surgical vs medical), complications, whether the disease recurred, disease-free interval, survival time, and cause of death.Results—Calculated proportions of dogs free from disease 1 year after treatment were 25 and 78%, respectively, for dogs treated medically and surgically. Treatment was 5.4 times as likely to fail in dogs treated medically as in dogs treated surgically. Two regression models relating treatment group (medical vs surgical) to disease-free interval were found to be significant. The first contained terms for medical treatment and isolation ofActinomycesspp from pleural fluid; the second contained terms for medical treatment and radiographic detection of mediastinal or pulmonary lesions at the time of initial examination.Conclusions and Clinical Relevance—Results suggest that surgical treatment is associated with a better outcome than medical treatment in dogs with pyothorax. In addition, surgery should be considered if radiographic evidence of mediastinal or pulmonary lesions is detected or ifActinomycesspp is isolated from the pleural fluid. (J Am Vet Med Assoc2002; 221:86–92)
Effects of lufenuron treatment in cats on the establishment and course of Microsporum canis infection following exposure to infected cats
Authors: DeBoer Douglas J. , Moriello Karen A. , Blum Jenifer L. , Volk Lynn M. 
Published: July 2006

AbstractObjective—To determine effects of lufenuron treatment in cats on the establishment and course ofMicrosporum canisinfection following exposure to infected cats.Design—Experimental trial.Animals—24 healthy juvenile domestic shorthair cats.Procedure—8 cats were given lufenuron PO (133 mg/cat/mo, equivalent to a dose of 100 to 130 mg/kg [45 to 59 mg/lb] at the beginning of the study and 25 to 35 mg/kg [11 to 16 mg/lb] at the end of the study), and 8 were given lufenuron SC (40 mg every 6 months). The remaining 8 were used as untreated control cats. After 4 months, cats were challenged by the introduction of cats with mild, experimentally inducedM canisinfection into the rooms where cats were housed. Extent of resulting infections in the naïve cats was monitored for 22 weeks by physical examination and fungal culture.Results—All lufenuron-treated and control cats became infected withM canis. Cats treated with lufenuron had significantly lower infection scores, compared with control cats, during the early weeks following exposure, and there was a more prolonged initial progression phase of the infection. Once infections reached peak intensity, they resolved over similar periods in lufenuron-treated and control cats.Conclusions and Clinical Relevance—Results suggested that oral or SC administration of lufenuron to cats, at the dosages used and under the conditions of this study, did not prevent establishment of dermatophytosis following exposure to infected cats. Infection was established more slowly among cats treated with lufenuron, but once established, infection resolved in approximately the same amount of time in lufenuron-treated as in control cats. (J Am Vet Med Assoc2003;222:1216–1220)