bluuebunny/crossref_metadata_2025_split huggingface dataset:
A wellbeing podcast for diagnostic radiography students
Authors: Girard Emily , Punch Amanda , Jimenez Yobelli 
Published: March 2024

AbstractIntroductionDiagnostic radiography students experience challenges during clinical placements, which have the potential to impact students' emotional wellbeing. This study aimed to explore radiography students' perception of the newly developed podcast series as a wellbeing support tool.MethodsA mixed methods study was conducted analysing data from listeners, including usage data from the podcast host site, surveys, and focus groups. Usage data was analysed descriptively. A bespoke survey, using a 5‐point Likert scale and fixed‐response questions was analysed descriptively. Two focus groups consisting of ten participants in total were conducted and data was analysed using thematic analysis.ResultsThere were 1201 downloads of the ‘Breathe‐in Radiography Podcast’ series across 20 countries and 17 platforms during the study period. A total of 66 complete survey responses demonstrated an overall positive perception of the podcast series. Five main themes were identified from the focus groups: integrated with other activities, accessed when experiencing emotional challenges, relatability to peers, impact on behaviour and mindset, and future podcast content.ConclusionsThis study demonstrated students' positive perceptions of a podcast for support during clinical placement. Further studies are needed to maximise the benefits of podcasting to radiography students and to establish a direct effect of podcasts on student wellbeing.
Early amyloid‐induced changes in microglia gene expression in male APP/PS1 mice
Authors: Oshima Takuya , Kater Mandy S. J. , Huffels Christiaan F. M. , Wesseling Evelyn M. , Middeldorp Jinte , Hol Elly M. , Verheijen Mark H. G. , Smit August B. , Boddeke Erik W. G. M. , Eggen Bart J. L. 
Published: March 2024

AbstractAlzheimer's disease (AD) is a progressive neurodegenerative disease and the most common cause of dementia, characterized by deposition of extracellular amyloid‐beta (Aβ) aggregates and intraneuronal hyperphosphorylated Tau. Many AD risk genes, identified in genome‐wide association studies (GWAS), are expressed in microglia, the innate immune cells of the central nervous system. Specific subtypes of microglia emerged in relation to AD pathology, such as disease‐associated microglia (DAMs), which increased in number with age in amyloid mouse models and in human AD cases. However, the initial transcriptional changes in these microglia in response to amyloid are still unknown. Here, to determine early changes in microglia gene expression, hippocampal microglia from male APPswe/PS1dE9 (APP/PS1) mice and wild‐type littermates were isolated and analyzed by RNA sequencing (RNA‐seq). By bulk RNA‐seq, transcriptomic changes were detected in hippocampal microglia from 6‐months‐old APP/PS1 mice. By performing single‐cell RNA‐seq of CD11c‐positive and negative microglia from 6‐months‐old APP/PS1 mice and analysis of the transcriptional trajectory from homeostatic to CD11c‐positive microglia, we identified a set of genes that potentially reflect the initial response of microglia to Aβ.
Fight Injustice with Darkness: The Effect of Early Life Adversity on Malevolent Creativity Behavior
Authors: Geng Yaoguo , Shi Yibo , Hu Wanying , Jin Wenjing , Zhang Yuwei , Zhan Tingting 
Published: March 2024

ABSTRACTTwo studies were conducted to investigate the relationship between Early Life Adversity and Malevolent Creativity as well as its underlying mechanism. Study 1 established a moderated mediation model to explore the mediating role of Belief in a Just World (BJW) and the moderating role of Dark Triad. A total of 353 college students (Mage = 21.25, SDage = 2.21, 58.9% women) were recruited to fill out questionnaires. The results showed that Early Life Adversity positively predicted Malevolent Creativity behavior and indirectly predicted Malevolent Creativity behavior through BJW. Dark Triad reduced the effects of Early Life Adversity on BJW and intensified the effects of Early Life Adversity on Malevolent Creativity behavior. Study 2 explored the effect of threatening BJW on Malevolent Creativity potential. A total of 180 participants (Mage = 20.53, SDage = 1.7, 64.4% women) were investigated with questionnaires and a Malevolent Creativity Problem‐Solving Task. Study 2 validated study 1 and illustrated that the Malevolent Creativity potential (including fluency, originality, and malevolence) was enhanced when Belief in a Just World was threatened. However, greater fluency was only observed in men. As a whole, these finding emphasizes the important linking role of BJW between Early Life Adversity and Malevolent Creativity, and Dark Triad and gender influence the expression of Malevolent Creativity as well.
Confucian Culture and Enterprise Strategic Change from a Perspective of the Golden Mean Ethics
Authors: Li Chao , Huo Mengjun , Jiang Yushi , Liu Renhuai 
Published: March 2024

AbstractAs an important informal system, the impact of Confucian culture on enterprise strategic change decision‐making and economic and social development is often ignored. By using the OLS method and drawing from publicly listed companies on China's Shanghai and Shenzhen stock markets from 2002 to 2020 as research samples, this article empirically analyzes the relationship between Confucian culture and enterprise strategic change from the perspective of the “golden mean” ethics (a Confucian moral standard and philosophy of conduct). The article also attends to the moderating effects of foreign culture shock and stock rights between the relationship of Confucian culture and enterprise strategic change. A key finding is that the ethical thought of “golden mean” and “harmony” contained in Confucian culture has an inhibitory effect on the initiation of enterprise strategic change. Foreign culture shock positively moderates the relationship between Confucian culture and enterprise strategic change. When “shocked” by dominant foreign cultures, the negative impact of Confucian culture on enterprise strategic change will be weakened. Moreover, unlike previous research findings based on agency theory that suggests how state ownership may retard corporate development, the authors found that in an informal institutional environment with a strong Confucian culture, stock rights can play a positive moderating role in the relationship between Confucian culture and enterprise strategic change. When an enterprise is state‐owned, the inhibitory effect of Confucian culture on enterprise strategic change will be weakened further.
Application of Platysma Myocutaneous Flap in Surgical Repair after T2‐3 Glottic Carcinoma Resection
Authors: Zhu Wenying , Liang Haifeng , Liang Faya , Chen Renhui , Zheng Shibei , Liang Wenting , Guan Zhong , Cai Qian 
Published: March 2024

ObjectiveNumerous methods and materials are available for vertical partial laryngectomy. In this study, the reparative effects of the platysma myocutaneous flap (PMF) and ribbon myocutaneous flap (RMF) on the postoperative voice quality of patients were compared to provide a reference for selecting a method conducive to improving postoperative voice quality.MethodsA retrospective analysis was performed on patients with unilateral T2‐3 glottic carcinoma. Following vertical partial laryngectomy, the defect was repaired with a PMF or simple RMF. Twelve months after surgery, voice quality was assessed according to voice acoustics, aerodynamics, and subjective perceptual evaluation, and glottic morphology was recorded using a laryngeal stroboscopy.ResultsA total of 70 patients were identified, including 54 in the PMF group and 16 in the RMF group. The PMF group was superior to the RMF group in terms of voice quality assessed by voice acoustics, aerodynamics, and subjective perceptual evaluation. In the PMF group, 72.2% of patients performed phonation with their vocal cords, and approximately 27.8% of patients were affected by supraglottic compression. In the RMF group, 81.3% of patients were affected by supraglottic compression. No significant difference was found in the 5‐year survival rate between the two groups.ConclusionFor defect repair following vertical partial laryngectomy, a PMF can allow better postoperative voice quality to be achieved than an RMF because a PMF can provide more tissue (including strap muscle under the flap) for padding, which enables the glottic portion corresponding to the vocal cord to close well.Level of Evidence3 Laryngoscope, 134:3181–3186, 2024
Changes in built‐up land along slope gradients and their effects on vegetation in the Three Gorges Reservoir Area
Authors: Zhang Haozhe , Yang Qingyuan , Tang Qiang , He Xiubin 
Published: March 2024

AbstractBuilt‐up land changes along slope gradients (BCSG) are widespread globally, driven by natural environmental and socio‐economic variations. This process has profound effects on vegetation cover and is closely related to the United Nations Sustainable Development Goals. However, the mechanisms involved in the BCSG remain to be elucidated, and the impacts of BCSG on vegetation cover need to be quantified. The BCSG from 1990 to 2020 was described through slope spectrum analysis by taking the Three Gorges Reservoir Area (TGRA) as an example. Then, the Normalized Difference Vegetation Index (NDVI) was used as an indicator of vegetation cover, and its influence by BCSG was explored through a multiple linear regression model. The built‐up land in the TGRA from 1990 to 2020 was first dominated by slope climbing (SC) and then by horizontal expansion, and the intensity of built‐up land SC showed a general trend of weakening over time. During the 30 years, the intensity of built‐up land SC weakened and then strengthened in townships with mainly intermountain plains, while gradually decreasing in townships with mainly hills and townships with mainly mountains. Socio‐economic factors, natural factors, and regional special events drive the BCSG in TGRA. Built‐up land SC in the TGRA will have a negative impact on NDVI but to a progressively lesser degree from 1990 through 2020. The built‐up land SC in townships with mainly hills and mountains has a negative effect on NDVI. The built‐up land SC in townships with mainly intermountain plains has a positive impact on NDVI. These results can provide a scientific basis for formulating reasonable vertical management policies for built‐up land and help reduce the ecological risks caused by land development.
Organic fermentative‐humic soil subhorizon (Ofh) as a ‘natural sponge’ of selected trace elements: Does this feature make it a potential geoindicator of temperate soil quality?
Authors: Dołęgowska Sabina , Sołtys Agnieszka , Krzciuk Karina 
Published: March 2024

AbstractIn a temperate climate zone, the outermost part of forest soil forms the organic‐O horizon. It consists of subhorizons of varying thickness, including the organic fermentative‐humic subhorizon (Ofh), which resembles a tobacco tangled mat. The scientific novelty of this project is to evaluate whether the specific structure of the subhorizon‐Ofh makes it a ‘natural sponge’ for trace elements such as Cd, Hg, Pb and Zn, and whether it can be used as a potential geoindicator of soil quality. To test this hypothesis, 110 soil samples (55 from the subhorizon‐Ofh and 55 from the underlying soil horizons‐A [humic] or AE [humic‐eluvial]) were collected from five forest areas located in the south‐central Poland (Świętokrzyskie province). All samples were analysed for Ba, Ca, Cd, Cu, Fe, Hg, K, Mn, Pb, S, Ti and Zn. pH, EC, soil organic matter, total C and N were also measured. Our results confirm that the subhorizon‐Ofh acts like the sponge in relation to Cd, Hg and Zn. Concentrations of these elements are two to four times higher than in the A and AE horizons. Such a relationship is not observed for Pb which predominates in the A horizon. This feature means that analyses of samples from different (sub)horizons can lead to misleading conclusions about soil quality and contamination levels, which have been verified by geochemical factors. Our results can be a starting point for further research into the possible use of the subhorizon‐Ofh as a geoindicator of temperate soil quality in relation to selected trace elements.
Greenhouse gas emissions (CO2–CH4–N2O) along a large reservoir‐downstream river continuum: The role of seasonal hypoxia
Authors: Wu Zetao , Yu Dan , Yu Qibiao , Liu Qian , Zhang Mingzhen , Dahlgren Randy A. , Middelburg Jack J. , Qu Liyin , Li Quanlong , Guo Weidong , Chen Nengwang 
Published: March 2024

AbstractRecent studies suggest that hypolimnetic respiration may be responsible for greenhouse gas (GHG) emissions from deep reservoirs. Currently, quantitative evaluation of aerobic vs. anaerobic processes and priming (enhanced processing of organic matter due to the addition of labile carbon) in regulating GHG production and emissions across the reservoir‐downstream continuum remains largely unknown. High‐resolution, annual time‐series observations in a large, subtropical reservoir (Shuikou) experiencing seasonal hypoxia in southeast China indicate that aerobic hypolimnetic CO2 production dominated in most periods of the stratified spring/summer with higher rates at higher temperatures. In addition, anaerobic production of hypolimnetic CO2 occurred in the late stratified spring/summer period, which stimulated hypolimnetic production of CH4 and N2O. Incubation experiments showed that priming in spring enhanced both aerobic and anaerobic production of excess GHGs. A late spring flood event generated the highest daily efflux of CO2 through the flushing of GHG‐enriched hypolimnion waters. Turbine degassing contributed 59%, 93%, and 63% of annual CO2, CH4, and N2O effluxes, respectively. Moreover, annual downstream GHG emissions were similar to those in the transition/lacustrine zone of the Shuikou reservoir. Diurnal variation observations revealed net CO2 emissions even during algal bloom seasons. The reservoir‐downstream river continuum was a year‐round source of GHGs (218.5 ± 18.9 Gg CO2‐equivalent yr−1; CO2 contributed 91%). However, the loss of oxygen also leads to increased production and storage of recalcitrant dissolved organic carbon (RDOC). Thus, identifying mechanisms controlling both GHG emissions and RDOC production is crucial to constrain the carbon neutrality issue of hydroelectric reservoirs in the context of climate change mitigation strategies.
Sonic branding: A narrative review at the intersection of art and science
Authors: Spence Charles , Keller Steve 
Published: March 2024

AbstractThe field of sonic branding/marketing has grown rapidly in recent years, as has commercial interest in more science‐based approaches to the practice, particularly as more brands and agencies look for qualitative and quantitative evidence to support the efficacy of sonic branding. In this research note, we explore the ways in which the design and execution (i.e., the “art”) of sonic branding initiatives can be informed by overlapping approaches and techniques drawn from the sciences, namely psychoacoustics, semiotics, music/auditory cognition, and crossmodal research. We explore whether the rapid growth of generative AI may represent the next major evolution in the design, creation, and assessment of sonic assets, where science and art are used to train AI tools that could one day augment (and potentially disrupt) the work of human sound designers and composers. These developments notwithstanding, it is argued that sonic branding will likely remain as much an art as a science, though basing one's approach on the emerging scientific literature ought to at least tilt the odds of success in the creative's favor.
ENO1 contributes to the gemcitabine resistance of pancreatic cancer through the YAP1 signaling pathway
Authors: Ma Hongqin , Kong Lulu , Liu Li , Du Yusheng , Zhu Xinguo , Wang Ji , Zhao Wenxing 
Published: March 2024

AbstractPancreatic cancer (PC), a leading cause of cancer‐related deaths, has a 5‐year survival rate of approximately 10%. α‐Enolase (ENO1) is a junction channel protein involved in tumor cell apoptosis and chemoresistance. However, the role of ENO1 in PC remains unclear. The expression and prognosis of ENO1 levels were determined in PC using public databases based on The Cancer Genome Atlas (TCGA) data sets. Cell viability, half maximal inhibitory concentration (IC50), autophagy, apoptosis, and autophagy markers were examined using cell counting kit‐8 (CCK‐8), transmission electron microscope, flow cytometry assays, and immunoblot, respectively. Using the Gene Expression Omnibus (GEO) and TCGA data sets, we found that ENO1 was significantly enriched in PC tumor tissues, and high expression levels of ENO1 were associated with an unfavorable prognosis. Whereas ENO1 silencing suppressed proliferation, autophagy, and induced cell apoptosis in PC cells, and inhibited tumor growth in vivo. Mechanistically, knockdown of ENO1 enhanced cellular cytotoxicity of gemcitabine (GEM), as well as reducing the expression of yes‐associated protein 1 (YAP1), a major downstream effector of the Hippo pathway in vitro. YAP1 promoted autophagy and protected PC cells from GEM‐induced apoptotic cell death. Furthermore, YAP1 overexpression attenuated the inhibition effects of ENO1 silencing. Our results suggest that ENO1 overexpression promotes cell growth and tumor progression by increasing the expression of YAP1 in PC. Further studies are required to understand the detailed mechanisms between ENO1 and YAP1 in PC.
Selling formats and platform information sharing under manufacturer competition
Authors: Li Xue , Tong Shilu , Cai Xiaoqiang , Chen Jian 
Published: March 2024

AbstractOnline retail platforms have increasingly utilized big data technologies to gather demand information, which is then shared with upstream manufacturers employing various selling modes, including a hybrid format that encompasses both direct and indirect selling. Previous studies have suggested that platforms should refrain from sharing demand information with manufacturers engaged in indirect selling. In this study, we present a game‐theoretic model to examine the factors influencing the online platform's decision to share information with an indirect selling manufacturer and under what conditions. Our initial analysis, considering exogenous selling formats in the base model, reveals that the platform's information sharing behavior is primarily influenced by selling format structures, commission fee rates, and competition intensity. The platform always has an incentive to share information with direct selling manufacturers; however, under a hybrid selling format, information sharing with indirect selling manufacturers may occur, particularly when both the commission fee rate and competition intensity are relatively high. We extend our investigation to explore the platform's optimal format‐dependent information sharing behavior, accounting for manufacturers' endogenous selling format decisions, and demonstrate the robustness of our main findings from the base model. Overall, our research offers valuable insights and guidelines to assist online platforms in making informed decisions about their information sharing practices.
From diversity to pluralism: Is everyone included?
Authors: Spanu Maja , Gill Laetitia 
Published: March 2024

AbstractThe article discusses the growing recognition of the importance of diversity, equity and inclusion in the philanthropic sector internationally. It explores how diversity goes beyond being a simple ‘buzzword’ and instead reflects the complex demographics and social structures in society. The article emphasises the need for philanthropic organisations to adapt to the world's complexity and address power dynamics and discrimination to fully embrace diversity. The authors highlight concrete methods that can be employed to foster more inclusive practices within organisations. They stress the significance of leadership vision and adaptability, as well as individual self‐reflection, in making progress towards greater inclusion of the diverse voices that make up our societies. Importantly, the article suggests that embracing discomfort and adopting a posture of humility is key for growth and change within organisations. The article discusses tools like the Wheel of Privilege and Power, which helps individuals understand their own privilege and position in society. The authors advocate for rigorously measuring diversity and discrimination in the workplace to develop action plans and implement concrete measures. They believe that research and practice should collaborate to collect and analyse data effectively. The article also mentions the need for collective and open conversations within the philanthropic sector, acknowledging historical inequalities and privileges. Overall, the article emphasises the importance of moving from diversity to pluralism in the philanthropic sector to ensure coherence and greater social justice in the pursuit of deep social change.
Assessment of crista galli morphology and morphometry in individuals with cleft lip and palate: A three‐dimensional analysis
Authors: Ozturk Taner , Soylu Sertan , Cukurluoglu Aykagan 
Published: March 2024

AbstractObjectiveThe crista galli (CG), located in the anterior cranial fossa and associated with the cranial structures here, is a bony prominence on the ethmoid bone. In this study, we aimed to examine the anatomical variations and pneumatization status of the CG in individuals with cleft lip and palate (CLP) and to compare them with those of individuals without CLP.Material and methodsData from 16‐ to 25‐year‐old individuals with non‐syndromic cleft lip and palate and control individuals without any syndrome or disease who underwent cone beam computed tomography were used. Measurement of the CG height (superoinferior, on the coronal section), width (laterolateral, on the axial section), and length (anteroposterior, on the axial section) dimensions. In addition, a categorical evaluation of CG morphology, CG pneumatization, olfactory fossa depth, and position of the CG in the ethmoid area (Keros classification) was performed.ResultsAlthough the superoinferior diameter and laterolateral diameter values of the CG did not differ between the groups, the anteroposterior diameter values were found to be significantly (p = 0.047) lower in individuals with CLP (11.95 ± 2.57 mm) compared with control (13.23 ± 2.05 mm). There was no difference in the morphology or pneumatization status of the CG between the groups.ConclusionExcept for the anteroposterior length, there was no difference in CG morphometric measurements between individuals with CLP and control. The anteroposterior length was shorter in individuals with CLP.