bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pub and community: The views of Birmingham untreated heavy drinkers
Authors: Orford Jim , Rolfe Alison , Dalton Sue , Painter Catherine , Webb Heather 
Published: November 2008

AbstractThis paper reports the results of a qualitative analysis of semi‐structured interviews with 79 members of the Birmingham Untreated Heavy Drinkers Cohort. The cohort was recruited in 1997 when all participants were drinking 50 or more standard units of alcohol (men) or 35 or more units (women) most weeks. Present interviews were carried out as part of the fourth wave of interviews, held in 2003. The topic was the participants' places of drinking in the community and the functions those places served. The present analysis focused on the relationship between pubs and community. The strongest theme to emerge was that the pub provided for many participants a real sense of community in itself. It did so by enabling participants to meet with like‐minded others, in a setting distinct from home or work, where conversing and confiding could take place in a relaxed atmosphere, with a range of other activities and forms of social support available to many. At the same time, participants were discriminating about which pubs they used, and when, and with whom they chose to interact. There was less consensus about whether the pub served a wider function by contributing to a positive sense of community in the local neighbourhood. It is suggested that English pubs, at least in a large conurbation such as the West Midlands, are very varied, sometimes continuing to serve as ‘the local’ for a community, sometimes being part of a variety of drinking places which between them provide people with a diversity of social niches to meet their increasingly diverse choices and preferences, and sometimes reflecting and even contributing to local community disorganisation. Copyright © 2008 John Wiley & Sons, Ltd.
Who are ethnocentric? Examining consumer ethnocentrism in Chinese societies
Authors: Hsu Jane Lu , Nien Han‐Peng 
Published: November 2008

Abstract

This study examined consumer ethnocentrism in Chinese societies and further to reveal whether more ethnocentric consumers would have higher preferences of domestic products. Multi‐item CETSCALE was applied in the study. Consumer surveys were administered in Taipei, Taiwan and in Shanghai, China, using stratified sampling method following the age and gender distributions of the populations between the ages of 15 and 64 in Taipei and in Shanghai. The differences in consumer ethnocentrism from respondents in Shanghai and in Taipei are that Shanghai respondents are more ethnocentric than Taipei respondents. Furthermore, ethnocentric consumers in Shanghai believe domestic brands of mobile phones are the best choices, while ethnocentric consumers in Taipei think domestic brands of mobile phones are the second best. Ethnocentrism has a strong influence on preferences of domestic brands. Ethnocentric consumers in both cities were relatively older, with lower educational levels, and had been travelling abroad fewer times in the past 3 years. Results of this study indicated that different patterns of consumer ethnocentrism existed in sub‐cultural Chinese societies.

Copyright © 2008 John Wiley & Sons, Ltd.
Importance of Translation–Replication Balance for Efficient Replication by the Self‐Encoded Replicase
Authors: Ichihashi Norikazu , Matsuura Tomoaki , Kita Hiroshi , Hosoda Kazufumi , Sunami Takeshi , Tsukada Koji , Yomo Tetsuya 
Published: November 2008

AbstractIn all living systems, the genetic information is replicated by the self‐encoded replicase (Rep); this can be said to be a self‐encoding system. Recently, we constructed a self‐encoding system in liposomes as an artificial cell model, consisting of a reconstituted translation system and an RNA encoding the catalytic subunit of Qβ Rep and the RNA was replicated by the self‐encoded Rep produced by the translation reaction. In this system, both the ribosome (Rib) and Rep bind to the same RNA for translation and replication, respectively. Thus, there could be a dilemma: effective RNA replication requires high levels of Rep translation, but excessive translation in turn inhibits replication. Herein, we actually observed the competition between the Rib and Rep, and evaluated the effect for RNA replication by constructing a kinetic model that quantitatively explained the behavior of the self‐encoding system. Both the experimental and theoretical results consistently indicated that the balance between translation and replication is critical for an efficient self‐encoded system, and we determined the optimum balance.
Comparison of Facially Amphiphilic versus Segregated Monomers in the Design of Antibacterial Copolymers
Authors: Gabriel Gregory J. , Maegerlein Janet A. , Nelson Christopher F. , Dabkowski Jeffrey M. , Eren Tarik , Nüsslein Klaus , Tew Gregory N. 
Published: November 2008

AbstractA direct comparison of two strategies for designing antimicrobial polymers is presented. Previously, we published several reports on the use of facially amphiphilic (FA) monomers which led to polynorbornenes with excellent antimicrobial activities and selectivities. Our polymers obtained by copolymerization of structurally similar segregated monomers, in which cationic and non‐polar moieties reside on separate repeat units, led to polymers with less pronounced activities. A wide range of polymer amphiphilicities was surveyed by pairing a cationic oxanorbornene with eleven different non‐polar monomers and varying the comonomer feed ratios. Their properties were tested using antimicrobial assays and copolymers possessing intermediate hydrophobicities were the most active. Polymer‐induced leakage of dye‐filled liposomes and microscopy of polymer‐treated bacteria support a membrane‐based mode of action. From these results there appears to be profound differences in how a polymer made from FA monomers interacts with the phospholipid bilayer compared with copolymers from segregated monomers. We conclude that a well‐defined spatial relationship of the whole polymer is crucial to obtain synthetic mimics of antimicrobial peptides (SMAMPs): charged and non‐polar moieties need to be balanced locally, for example, at the monomer level, and not just globally. We advocate the use of FA monomers for better control of biological properties. It is expected that this principle will be usefully applied to other backbones such as the polyacrylates, polystyrenes, and non‐natural polyamides.
Space‐ and Time‐Resolved In‐situ Spectroscopy on the Coke Formation in Molecular Sieves: Methanol‐to‐Olefin Conversion over H‐ZSM‐5 and H‐SAPO‐34
Authors: Mores Davide , Stavitski Eli , Kox Marianne H. F. , Kornatowski Jan , Olsbye Unni , Weckhuysen Bert M. 
Published: November 2008

AbstractFormation of coke in large H‐ZSM‐5 and H‐SAPO‐34 crystals during the methanol‐to‐olefin (MTO) reaction has been studied in a space‐ and time‐resolved manner. This has been made possible by applying a high‐temperature in‐situ cell in combination with micro‐spectroscopic techniques. The buildup of optically active carbonaceous species allows detection with UV/Vis microscopy, while a confocal fluorescence microscope in an upright configuration visualises the formation of coke molecules and their precursors inside the catalyst grains. In H‐ZSM‐5, coke is initially formed at the triangular crystal edges, in which straight channel openings reach directly the external crystal surface. At reaction temperatures ranging from 530 to 745 K, two absorption bands at around 415 and 550 nm were detected due to coke or its precursors. Confocal fluorescence microscopy reveals fluorescent carbonaceous species that initially form in the near‐surface area and gradually diffuse inwards the crystal in which internal intergrowth boundaries hinder a facile penetration for the more bulky aromatic compounds. In the case of H‐SAPO‐34 crystals, an absorption band at around 400 nm arises during the reaction. This band grows in intensity with time and then decreases if the reaction is carried out between 530 and 575 K, whereas at higher temperatures its intensity remains steady with time on stream. Formation of the fluorescent species during the course of the reaction is limited to the near‐surface region of the H‐SAPO‐34 crystals, thereby creating diffusion limitations for the coke front moving towards the middle of the crystal during the MTO reaction. The two applied micro‐spectroscopic techniques introduced allow us to distinguish between graphite‐like coke deposited on the external crystal surface and aromatic species formed inside the zeolite channels. The use of the methods can be extended to a wide variety of catalytic reactions and materials in which carbonaceous deposits are formed.
Influence of Endohedral Confinement on the Electronic Interaction between He atoms: A He2@C20H20Case Study
Authors: Cerpa Erick , Krapp Andreas , Flores‐Moreno Roberto , Donald Kelling J. , Merino Gabriel 
Published: November 2008

AbstractThe shortest He–He distance!r(He–He)=1.265 Å. The electronic interaction between confined pairs of He atoms in the C20H20dodecahedrane cage is analyzed (see figure). A key observation about bonding that emerges uniquely from endohedral complexes is that a short internuclear separation does not necessarily imply the existence of a chemical bond.magnified imageThe electronic interaction between confined pairs of He atoms in the C20H20dodecahedrane cage is analyzed. The He–He distance is only 1.265 Å, a separation that is less than half the He–He distance in the free He dimer. The energy difference between the possible isomers is negligible (less than 0.15 kcal mol−1), illustrating that there is a nearly free precession movement of the He2fragment around its midpoint in the cage. We consider that a study of inclusion complexes, such as the case we have selected and other systems that involve artificially compressed molecular fragments, are useful reference points in testing and extending our understanding of the bonding capabilities of otherwise unreactive or unstable species. A key observation about bonding that emerges uniquely from endohedral (confinement) complexes is that a short internuclear separation does not necessarily imply the existence of a chemical bond.
All‐Optical Integrated Logic Operations Based on Chemical Communication between Molecular Switches
Authors: Silvi Serena , Constable Edwin C. , Housecroft Catherine E. , Beves Jonathon E. , Dunphy Emma L. , Tomasulo Massimiliano , Raymo Françisco M. , Credi Alberto 
Published: November 2008

AbstractMolecular logic gates process physical or chemical “inputs” to generate “outputs” based on a set of logical operators. We report the design and operation of a chemical ensemble in solution that behaves as integrated AND, OR, and XNOR gates with optical input and output signals. The ensemble is composed of a reversible merocyanine‐type photoacid and a ruthenium polypyridine complex that functions as a pH‐controlled three‐state luminescent switch. The light‐triggered release of protons from the photoacid is used to control the state of the transition‐metal complex. Therefore, the two molecular switching devices communicate with one another through the exchange of ionic signals. By means of such a double (optical–chemical–optical) signal‐transduction mechanism, inputs of violet light modulate a luminescence output in the red/far‐red region of the visible spectrum. Nondestructive reading is guaranteed because the green light used for excitation in the photoluminescence experiments does not affect the state of the gate. The reset is thermally driven and, thus, does not involve the addition of chemicals and accumulation of byproducts. Owing to its reversibility and stability, this molecular device can afford many cycles of digital operation.
The Synthesis and Characterisation of a Free‐Base Porphyrin–Perylene Dyad that Exhibits Electronic Coupling in Both the Ground and Excited States
Authors: Mathew Simon , Johnston Martin R. 
Published: November 2008

AbstractA covalent dyad composed of a free‐base porphyrin and a perylene diimide (1) was synthesised and characterised by NMR, HRMS, UV/Vis and fluorometric methods. UV/Vis spectrophotometric analysis indicated a moderate coupling between the components in the ground state. Fluorescence spectroscopy revealed that the emissive properties of the dyad showed that the quantum yield of emission from the porphyrin Soret band increased dramatically and could not be rationalised by a straightforward photoinduced energy (and/or electron) transfer, but rather a coupling of excited states.
Mono‐ and Bis(tetrathiafulvalene)‐1,3,5‐Triazines as Covalently Linked Donor–Acceptor Systems: Structural, Spectroscopic, and Theoretical Investigations
Authors: Riobé François , Grosshans Philippe , Sidorenkova Helena , Geoffroy Michel , Avarvari Narcis 
Published: November 2008

AbstractReaction of 2,4,6‐trichloro‐1,3,5‐triazine with lithiated tetrathiafulvalene (TTF) in stoichiometric conditions, followed by treatment with sodium methanolate, provides mono‐ and bis(TTF)–triazines as new covalently linked (multi)donor–acceptor systems. Single‐crystal X‐ray analyses reveal planar structures for both compounds, with formation of peculiar segregated donor and acceptor stacks for the mono(TTF)–triazine compound, while mixed TTF–triazine stacks establish in the case of the bis(TTF) derivative. Cyclic voltammetry measurements show reversible oxidation of the TTF units, at rather low potential, with no splitting of the oxidation waves in the case of the dimeric TTF, whereas irreversible reduction of the triazine core is observed. Intramolecular charge transfer is experimentally evidenced through solution electronic absorption spectroscopy. Time‐dependent DFT calculations allow the assignment of the charge transfer band to singlet transitions from the HOMO of the donor(s) to the LUMO of the acceptor. Solution EPR measurements correlated with theoretical calculations were performed in order to characterize the oxidized species. In both cases the spectra show very stable radical species and contain a triplet of doublet pattern, in agreement with the coupling of the unpaired electron with the three TTF protons. The dication of the bis(TTF)–triazine is paramagnetic, but no spin–spin exchange interaction could be detected.
Finiteness of variance is irrelevant in the practice of quantitative finance
Authors: Taleb Nassim Nicholas 
Published: November 2008

AbstractOutside the Platonic world of financial models, assuming the underlying distribution is a scalable “power law,” we are unable to find a consequential difference between finite and infinite variance models—a central distinction emphasized in the econophysics literature and the financial economics tradition. Although distributions with power law tail exponents α > 2 are held to be amenable to Gaussian tools, owing to their “finite variance,” we fail to understand the difference in the application with other power laws (1 < α < 2) held to belong to the Pareto‐Lévy‐Mandelbrot stable regime. The problem invalidates derivatives theory (dynamic hedging arguments) and portfolio construction based on mean‐variance. This article discusses methods to deal with the implications of the point in a real world setting. © 2008 Wiley Periodicals, Inc. Complexity, 2009
Realizations of fully differential voltage second generation current conveyor with an application
Authors: Sobhy Ehab A. , Soliman Ahmed M. 
Published: November 2008

AbstractThree novel CMOS realizations for the fully differential voltage second‐generation inverting current conveyor (FDVCCII‐) are proposed in this paper. The first realization has a limited input range, and the other two realizations have a rail to rail input range and show excellent features in linearity and bandwidth. As an application to the FDVCCII‐, a floating gyrator is proposed. A floating inductor is realized using the floating gyrator and it is used in realizing a second‐order low‐pass filter, which is simulated and compared with the ideal result. All circuits are simulated with SPICE using CMOS 0.35µm technology and supply voltages ±1.5V to verify the theoretical results. Copyright © 2008 John Wiley & Sons, Ltd.
Fine‐needle aspiration of cystic pancreatic mucinous tumor: Oncotic cell as an aiding diagnostic feature in paucicellular specimens
Authors: Xiao Guang‐Qian 
Published: November 2008

AbstractIn juxtaposition with imaging studies, endoscopic ultrasound‐guided fine‐needle aspiration has gained popularity in the initial evaluation of pancreatic masses, especially cystic lesions of pancreas. Cystic pancreatic mucinous tumors include mucinous cystic neoplasm and intraductal papillary mucinous tumor, both of which have been known to have a low malignant potential and a high rate of association with invasive adenocarcinoma. As such, preoperative diagnosis is of great significance in guiding patient management. Although fine‐needle aspiration cytological diagnosis of pancreatic tumor in cellular specimens has been well described, as with other cystic lesions, the yield of diagnostic cells from needle aspiration of cystic pancreatic mucinous tumors is typically low. Cytological diagnosis from these paucicellular specimens remains challenging. An additional compounding problem is the high frequency of gastrointestinal mucin and epithelial contamination. The diagnostic morphology and criteria in these paucicellular specimens have not been well addressed in the literature. The cytopathologists' ongoing efforts tend to improve the diagnostic accuracy. In this current study, oncotic cells, characterized by cytoplasmic swelling and karyolysis, were analyzed from 17 cases of cystic pancreatic mucinous tumor, of which the diagnosis was either confirmed by surgical resection or supported by cell block and/or increased CEA. Oncotic cells were found in variable amounts in almost all the cystic pancreatic mucinous tumors in this series. None of the five fine‐needle aspirations intended for aspirations of hypoechoic nonlesional pancreas, which yielded either gastrointestinal tract material only or admixture of gastrointestinal and normal pancreatic components, was found to contain oncotic cells, evidencing the utility of oncotic cell as a surrogate morphologic marker in aiding the diagnosis of cystic pancreatic mucinous tumor as well as its differentiation from gastrointestinal contaminant, particularly in paucicellular specimens. Diagn. Cytopathol. 2009. © 2008 Wiley‐Liss, Inc.
Ductopapillary apocrine carcinoma of the eyelid metastatic to the parotid gland: Report of a case diagnosed by fine‐needle aspiration biopsy
Authors: Akhtar Israh , Ispas Cristina Luminita , Flowers Rhyne , Siddiqi Anwer , Young LaFarra , Donnellan Kimberly A. , Heard Ken , Baliga Mithra 
Published: November 2008

AbstractDuctopapillary apocrine carcinoma (DPAC) of the eyelid is a rare malignant neoplasm in the periocular region. The relative rarity of this tumor is a diagnostic challenge to the cytopathologist, especially when present as a metastatic lesion to an intraparotid lymph node, where the differential diagnosis includes primary parotid neoplasms, as well as various other metastatic malignancies. There are only a few reported cases of recurrent and metastatic DPAC of the eyelid, and to our knowledge, metastatic DPAC diagnosed by fine‐needle aspiration biopsy (FNAB) has not been described. We report a case of a 65‐year‐old African‐American male with a history of ductopapillary apocrine adenocarcinoma of the eyelid, diagnosed 6 weeks ago now presenting with a recurrence in the same area. Magnetic resonance imaging of the head and neck revealed an intraparotid mass also. FNAB of the parotid mass showed a well‐differentiated papillary adenocarcinoma with a cystic component, similar to a previously excised ductopapillary apocrine adenocarcinoma of the eyelid. Diagn. Cytopathol. 2009. © 2008 Wiley‐Liss, Inc.
Utility of the thromboplastin‐plasma cell‐block technique for fine‐needle aspiration and serous effusions
Authors: Kulkarni Manisha B. , Desai Sangeeta B. , Ajit Dulhan , Chinoy R. F. 
Published: November 2008

Abstract(I) To assess the feasibility of thromboplastin‐plasma (TP) method for cell block, (II) to concentrate the minimal cellular material from effusions and needle‐rinses by block preparation and improve visual details, (III) to compare conventional cytological smears with cell blocks for final assessment, and (IV) to assess utility of immunocytochemistry (ICC) for diagnostic accuracy.Seventy cell blocks were prepared by TP technique using surplus fluid from 38 serous effusions, and for 32 ultrasonography‐guided fine‐needle aspiration cytology (FNAC) material, rinses of syringes and needles were collected in normal saline after conventional cytological smears. Then, cell blocks were compared with conventional smears for adequacy, morphologic preservation, and ICC.Absolute concordance seen in 66 cases (94%) between the smears and cell blocks. Advantages with the blocks were cellular concentration in a limited field and better cellular preservation with architectural pattern. Quality of ICC was comparable to that of standard controls. Diagnostic discrepancy was seen in two cases where cell blocks were positive but smears were negative. Two cell blocks were nonrepresentative.Cell block serves as a useful adjunct to traditional cytological smears. TP method is simple, cost effective, and reproducible. It is easy when compared with agar‐embedding technique. Ancillary techniques like ICC can be performed successfully. Diagn. Cytopathol. 2009. © 2008 Wiley‐Liss, Inc.
Impact of ASC‐H terminology on the detection of HSILs in medically underserved California women
Authors: Howell Lydia Pleotis , Gurusinghe Sunitha , Tabnak Farzaneh 
Published: November 2008

AbstractIn this study we evaluated CDP: EWC, a large public health screening program for low‐income women to determine whether the ASC‐H term, introduced in the 2001 revision to the Bethesda System, has facilitated the detection of the most serious precancerous cervical lesions such as CIN‐II–III/CIS, including accuracy of detection and minimizing diagnostic delays. Pap test and biopsy data from the period 2003–2006 were compared with those from 1995–1999, and included analysis of a subset of rarely and never‐screened for each study period. More ASC‐H Pap tests were followed by CIN‐II+ biopsies (20%) than ASCUS Pap tests (5%). Thirteen percent of ASC‐H showed CIN‐III/CIS on follow‐up biopsy. Following the introduction of ASC‐H, negative and LSIL Pap tests followed by CIN‐III/CIS biopsies decreased from 5.6% to 0.37% and 9.2% to 4.4%, respectively. Fewer CIN‐III/CIS cases were preceded by Pap tests with negative and ASCUS results in 2003–2005 as compared with 1995–1999. The number of days from screening to diagnosis for women aged 25–39 years with ASC‐H Pap test results (58 days) was less than for ASCUS results (78 days) for the current study period. In this high‐risk multi‐ethnic population, ASC‐H more effectively communicates equivocal findings likely to represent HSIL leading to more rapid follow‐up. The incidence of CIN‐II or CIN‐III/CIS following ASC‐H Pap tests is lower than generally appreciated for this population, including for rarely or never‐screened high‐risk women. Fewer CIN‐III/CIS lesions were detected following negative and ASCUS Pap results. Compliance with follow‐up is less than ideal for this population. Diagn. Cytopathol. 2009. © 2008 Wiley‐Liss, Inc.
Paediatric cutaneous blastomycosis: A rare case diagnosed on FNAC
Authors: Shukla Shailaja , Singh Smita , Jain Manjula , Kumar Singh Sanjeet , Chander Ram , Kawatra Neha 
Published: November 2008

AbstractBlastomycosis, usually presenting as pneumonia, is more common in adults than in children. Moreover, cutaneous blastomycosis is quite uncommon in children. We describe a case of cutaneous blastomycosis in an 8‐year‐old boy who presented with multiple hyperkeratotic verrucous plaques where diagnosis was made on fine‐needle aspiration cytology, and the infection responded well to oral itraconazole therapy with reduction in number of spores and size of lesions. Diagn. Cytopathol. 2009. © 2008 Wiley‐Liss, Inc.