bluuebunny/crossref_metadata_2025_split huggingface dataset:
Preparation and radiosynthesis of [18F]FE@CFN (2-[18F]fluoroethyl 4-[N-(1-oxopropyl)-N-phenylamino]-1-(2-phenylethyl)-4-piperidinecarboxylate): a potential μ-opioid receptor imaging agent
Authors: Wadsak Wolfgang , Key Mien Leonhard , Ettlinger Dagmar E. , Feitscher Sylvia , Lanzenberger Rupert , Marton Janos , Dudczak Robert , Kletter Kurt , Mitterhauser Markus 
Published: January 2007

PET imaging of the μ-opioid receptor (OR) is still restricted to [11C]carfentanil ([11C]CFN) but its use is limited due to its short half-life and high agonistic potency. Recently, the radiosynthesis of [18F]fluoroalkyl esters of CFN was proposed, unfortunately yielding products not suitable for human PET due to their low specific activities. Therefore, our rationale was to develop a reliable radiosynthesis of a [18F]fluoroethylated CFN derivative overcoming these drawbacks.
The [18F]fluoroethyl ester of carfentanil, [18F]FE@CFN (2-[18F]fluoroethyl 4-[N-(1-oxopropyl)-N-phenylamino]-1-(2-phenylethyl)-4-piperidinecarboxylate), and its corresponding inactive standard compound were prepared. Purification of [18F]FE@CFN was achieved via a simple solid phase extraction method. [18F]FE@CFN was prepared with excellent purity (> 98%) and sufficient yields. Specific activity surpassed the level required for safe administration. We therefore conclude that our simplified synthesis of [18F]FE@CFN, for the first time, overcomes the shortcomings of [11C]CFN and the previously suggested alternatives, namely, (1) longer half-life; (2) easy production and (3) adequate specific activity, should make a wider application possible. Hence, [18F]FE@CFN may become a valuable PET tracer for the imaging of the μ-OR in human brain and heart.
Frequency of Attendance at Religious Services, Cardiovascular Disease, Metabolic Risk Factors and Dietary Intake in Americans: An Age-Stratified Exploratory Analysis
Authors: Obisesan Thomas , Livingston Ivor , Trulear Harold Dean , Gillum Frank 
Published: January 2007

Background: Few data have been published on the association of attendance at religious services with cardiovascular morbidity and dietary and metabolic risk factors in representative samples of populations despite a known inverse association with mortality and smoking. Objective: To test the null hypothesis that frequency of attendance at religious services is unrelated to prevalence or levels of cardiovascular disease, dietary and metabolic risk factors. Design: Cross-sectional survey of a large national sample. Participants: American men and women aged 20 years and over with complete data in the Third National Health and Nutrition Examination Survey ( n = 14,192). Measurements: Self-reported frequency of attendance at religious services, history of doctor-diagnosed diseases, food intake frequency, 24-hour dietary intake, health status, socio-demographic variables and measured serum lipids and body mass index. Results: Weekly attenders were significantly less likely to report stroke, even after adjusting for multiple variables only in African American women OR=0.35, 95% CI 0.19–0.66, p < 0.01. No association was seen for heart attack or diabetes. Fish intake at least weekly was more common in weekly attenders, significantly so only in African American women (odds ratio 1.24, 95% CI 1.01–1.58, p < 0.05) and in older Mexican American men (odds ratio 2.57, 95% CI 1.45–2.57, p < 0.01). In linear regression analyses, no significant independent associations were seen between attendance frequency and serum lipid levels or dietary intake of energy, or fat in g and % of kcal. Conclusion: Hypotheses generated by these analyses are that in African American women stroke is less prevalent and weekly fish intake more prevalent among weekly attenders than others and that there are no significant independent associations of serum lipids, dietary intake, prevalent CHD, or diabetes with frequency of attendance of religious services. Independent testing of these hypotheses in other samples is needed.
Small area estimation with auxiliary survey data
Authors: Lohr Sharon L. , Prasad N. G. N. 
Published: January 2007

AbstractLarge governmental surveys typically provide accurate national statistics. To decrease the mean squared error of estimates for small areas, i.e., domains in which the sample size is small, auxiliary variables from administrative records are often used as covariates in a mixed linear model. It is generally assumed that the auxiliary information is available for every small area. In many cases, though, such information is available for only some of the small areas, either from another survey or from a previous administration of the same survey. The authors propose and study small area estimators that use multivariate models to combine information from several surveys. They discuss computational algorithms, and a simulation study indicates that if quantities in the different surveys are sufficiently correlated, substantial gains in efficiency can be achieved.
Influence of metal and ligand types on stacking interactions of phenyl rings with square-planar transition metal complexes
Authors: Sredojević Dušan , Tomić Zoran , Zarić Snezana 
Published: January 2007

AbstractIn order to find out whether metal type influences the stacking interactions of phenyl rings in square-planar complexes, geometrical parameters for Cu, Ni, Pd and Pt complexes, with and without chelate rings, were analyzed and compared. By searching the Cambridge Structural Database, 220 structures with Cu complexes, 211 with Ni complexes, 285 with Pd complexes, and 220 with Pt complexes were found. The results show that the chelate ring has a tendency to make the stacking interaction with the phenyl ring independent of metal type in the chelate ring. However, there are some differences among metals for complexes without a chelate ring. There are a number of structures containing Pd and Pt complexes, without chelate rings, that have short carbon-metal distances and parallel orientations of the phenyl ring with respect to the coordination plane. It was found that some of these complexes have a common fragment, CN, as a part of the ligands. This indicates that the CN supports stacking interactions of square planar complexes with the phenyl ring.
Copper(II) complexes of the antihypertensive drug nadolol
Authors: Getova Valentina , Pantcheva Ivayla , Ivanov Darvin , Mehandjiev Dimitar , Skumryev Vassil , Bontchev Panayot 
Published: January 2007

AbstractThe complexation of the non-selective β-blocker nadolol, HL, 1 with copper(II) leads to formation of mono-and dinuclear complexes depending mainly on the metal-to-ligand molar ratio. The mononuclear violet complex CuL2·2Solv, 2, was obtained in a soluble form at metal-to-ligand molar ratio Cu(II): HL ≤ 1: 10 in methanolic or slightly alkaline aqueous solutions. The dinuclear green complex Cu2L2Cl2·H2O, 3 was synthesized at Cu(II): HL ≥ 1: 2 molar ratio in methanolic solutions. The complexes were studied using spectral (UV-Vis, FT-IR, EPR), magnetochemical, thermogravimetric methods and elemental analysis. In the complexes nadolol acts as a monoanionic bidentate ligand coordinated to copper(II) through the NH-and the deprotonated OH-groups of its aminoalcohol fragment.
Scaling up Simultaneous Exfoliation and 2H to 1T Phase Transformation of MoS2
Authors: Kiran Patlolla Sai , Kumar Krishnappagari Vijay , Pandit Niranjan , Indupuri Satish , Kumar Rahul , Wagh Vedant Vinod , Islam Aminul , Keshri Anup Kumar 
Published: March 2024

AbstractLarge‐scale production of high‐quality ultrathin layers (1–3 nm) of molybdenum disulfide (MoS2) with absolute (≈100%) 1T‐phase is still in its infancy. Therefore, it is extremely crucial to have a technique for the mass production of ultrathin 1T‐MoS2 layers. Here, a direct, single‐step, and ultra‐fast technique that produces high‐quality ultrathin layers of 1T‐MoS2 with a production rate as high as 58 g h−1 without the usage of any intercalates or solvents is demonstrated. The exfoliated ultrathin 1T‐MoS2 layers exhibited ≈100% 1T‐phase with a large specific surface area (67 m2 g−1), higher electrical conductivity (140 S m−1), high thermal stability (up to 500 °C) and hydrophilicity (water contact angle (WCA): ≈23.4⁰). The ultrathin 1T‐MoS2 layers showed a higher specific capacitance of 420 F g−1; perhaps an ideal candidate for the electrodes of supercapacitors. Moreover, the ultrathin 1T‐MoS2 layer exhibited better mechanical flexibility and retained its original performance on bending between 0 and 180⁰ angles. Further, to assess the adeptness of the protocol, An initial trial is done on other transition metal dichalcogenides (TMDs) i.e., tungsten disulfide (WS2), and observe similar results. The work sheds light on the simultaneous exfoliation and phase transformation of TMDs in large quantities, and detailed proofs‐of‐concept demonstrate its application in next‐generation energy storage devices.
Dynamic Ionic Liquids‐Based Conductive Coatings for Customizable, Integrated and Recyclable Printed Circuit Boards
Authors: Chen Zhiwu , Song Chenhao , Lian Xiaodong , Xu Beihang , Wang Yapei 
Published: March 2024

AbstractGiven the pollution and waste of resources caused by electronic waste, the search for recyclable alternatives to printed circuit boards (PCBs) is an attractive approach to alleviating this situation. For the next generation of recyclable integrated PCBs, it is imperative to further consider both the recyclability of the integrated electronics and the appropriate welding technique. Herein, a fully dynamic ionic network based on dynamic ionic liquids and dynamic cross‐linkers is developed as the host of PCBs, while liquid metal droplets, which can be easily recycled, are selected as conductive fillers. By virtue of concentration‐induced polymerization, a conductive coating can be obtained after solvent evaporation, which exhibits outstanding adhesion to multiple substrates. Furthermore, conductive circuits can be customized by activating the conductivity of liquid metal droplets under patterned pressure. The fully dynamic ionic network can also function as versatile electronics that can be easily integrated into PCBs through healing welding. It demonstrates the ability to provide 2D imaging of pressure and temperature distributions. Owing to the multiple stimulation responses of the abundant disulfide bonds, the fully dynamic ionic network exhibits intrinsic recyclability, and the disulfide bonds can also be degraded by reducing reagents to achieve the recycling of the embedded liquid metal.
Elastic Polarization Configuration Coupled with Activity Rattling Space Boosts Energy Harvesting Performance of Lead‐Free Piezoceramic
Authors: Xi Kaibiao , Hou Yudong , Zheng Mupeng , Zhu Mankang 
Published: March 2024

AbstractPiezoelectric energy harvesting technology is drawing substantial attention as an eco‐friendly method to promote energy transformation, which is at the forefront of current scientific research. However, the difficulties involved in obtaining a stable output voltage (Vout) and a controllable output current density (Iout) represent bottlenecks in the development of piezoelectric energy harvesters (PEHs) for practical applications. Here, a novel strategy that couples elastic polarization configuration with activity rattling space in lead‐free potassium sodium niobate‐based piezoceramics is proposed to break through this barrier. The cantilever beam‐type PEHs assembled using the rationally designed piezoceramic system show a stable Vout (≈22 V) and a controllable Iout over the range from 6.09 to 20.16 µA cm−2, which is sufficient to drive multiple types of wireless sensors that have the same rated voltage but different rated current requirements. These fantastic power generation performances are associated with a stable piezoelectric voltage coefficient (g33), an increasing piezoelectric charge coefficient (d33), and a weakened electrostrictive coefficient (Q33) that stem from polarization configuration optimization in combination with introduction of the activity rattling space design. This work provides a good approach to modulation of the overall performance of piezoelectric materials to meet the demands of advanced PEH applications.
Achieving Zero‐Temperature Coefficient Point Behavior by Defect Passivation for Temperature‐Immune Organic Field‐Effect Transistors
Authors: Qi Jiannan , Tie Kai , Ma Yue , Huang Yinan , Gong Wenbing , Sun Shougang , Wang Zhongwu , Li Zhiyun , Huang Rong , Bi Jinshun , Li Liqiang , Chen Xiaosong , Hu Wenping 
Published: March 2024

AbstractOrganic field‐effect transistors (OFETs) have broad prospects in biomedical, sensor, and aerospace applications. However, obtaining temperature‐immune OFETs is difficult because the electrical properties of organic semiconductors (OSCs) are temperature‐sensitive. The zero‐temperature coefficient (ZTC) point behavior can be used to achieve a temperature‐immune output current; however, it is difficult to achieve in organic devices with thermal activation characteristics, according to the existing ZTC point theory. Here, the Fermi pinning in OSCs is eliminated using the defect passivation strategy, making the Fermi level closer to the tail state at low temperatures; thus threshold voltage (VT) is negatively correlated with temperature. ZTC point behaviors in OFETs are achieved by compensation between VT and mobility at different temperatures to improve its temperature immunity. A temperature‐immune output current can be realized in a variable‐temperature bias voltage test over 50000 s by biasing the device at the ZTC point. This study provides an effective solution for temperature‐immune OFETs and inspiration for their practical application.
Large‐Scale, Stretchable, Self‐Protective, and Multifunctional Perovskite Luminescent Filament with Ultra‐High Stability
Authors: Yang Liyan , Liu Yunpeng , Li Xiaofang , Li Mufang , Li Wei , Wang Tao , Wang Dong 
Published: March 2024

AbstractLead halide perovskites possess great application potential in flexible displays and wearable optoelectronics owing to their prominent optoelectronic properties. However, the intrinsic instability upon moisture, heat, and ultraviolet (UV) light irradiation hinders their development and application. In this work, an ultra‐stable CsPbX3 (X = Cl, Br, I) perovskite luminescent filament (PLF) with high stretchability (≈2400%) and luminescence performance (photoluminescence quantum yield (PLQY) of 24.5%, tunable emission spectrum, and high color purity) is introduced by a facile environmental‐friendly wet‐spinning technology via solvent extraction. Benefiting from the in situ encapsulation of the hydrophobic thermoplastic polyurethane (TPU) and the chelation of Lewis base CO in TPU with Lewis acid Pb2+, the CsPbBr3 PLF demonstrates ultra‐high photoluminescence (PL) stability when stored in ambient air and high humidity circumstance, annealed at 50 °C, and dipped in water for 30 days, illuminated under ultraviolet light for 300 min, and immersed in organic solvents and solutions with pH of 1‐13 for 5 min, respectively. Impressively, it retains 80% of its initial PL after being recycled five times. Overall, the CsPbX3 PLF demonstrates promising prospects in multifunctional applications, including organic dyes and tensile strain sensing, flexible pattern displays, secondary anti‐counterfeiting, and hazard warning systems.
Floating Solar Materials and their Devices for Energy Conversion and Environment Remediation
Authors: Liu Xinyi , Pan Junan , Huang Hao , Sun Ning , Gu Chen , Zhuang Yanling , Wang Longlu 
Published: March 2024

AbstractFloating solar materials and their devices, which can effectively solve the problems faced by powder solar materials, such as difficult recycling, poor stability, and difficult maintenance, have received widespread attention in recent years. However, it is still in the early stage of development and still faces many challenges in material design, device preparation, and systematic application. Therefore, it is particularly necessary to summarize the research progress of related aspects to promote the development of this field (To achieve large‐scale applications, it is necessary to develop devices that can be applied on a large scale). In this review, the systematic construction methods of floating materials are reviewed from the aspects of lightweight carrier integration as well as functionalization and surface modification. Subsequently, the recent studies on floating solar materials and their devices are categorized and summarized. Their applications in the purification of polluted seawater, water splitting, CO2 reduction, and prevention of water bloom are reviewed in detail. Finally, the outlook for future development is critically discussed.
Integrated System of Mechanical Regulator and Electrical Circuitry on Triboelectric Energy Harvesting with Near‐Field Communication for Low Power Consumption
Authors: Hwang Hee Jae , Kwon Daehyeok , Kwon Hee‐Young , Shim Minseob , Baik Jeong Min , Choi Dukhyun 
Published: March 2024

AbstractThis paper presents an integrated power generation, conversion, and storage system with a temperature monitoring system, including passive near‐field communication (PGCS‐TMS‐pNFC), based on triboelectric nanogenerators (TENGs). The system consists of three parts; first, a mechanical regulation system (MRS) with kinematic design and multiphase control; second, a phase control rectifying circuit (PCRC) with a battery charging circuit (BCC); and third, a data processing and communication system (TMS‐pNFC) for low power consumption. The MRS, consisting of a reel spring and gear train, achieves a high‐frequency output exceeding 1000 Hz, and long‐lasting operation. PCRC provides stable and minimizing fluctuated DC output with a ripple effect as RMS voltage and current of 423 V and 46 µA, for 2 s, with a crest factor of 1.15 and 1.08. The PGCS‐TMS‐pNFC, harvesting building energy, such as opening and closing doors, is used to sense and store temperature data for more than 29 min, and the data is transmitted to the receiver via pNFC through smartphone tagging. Additionally, the PGCS with BCC is implemented on a bicycle frame to charge electronic devices while riding. This research underscores the integrated approach and practical applications of TENG technology that contribute to energy efficiency and sustainability in the lives.
Association between hippocampal microglia, AD and LATE‐NC, and cognitive decline in older adults
Authors: Kapasi Alifiya , Yu Lei , Leurgans Sue E , Agrawal Sonal , Boyle Patricia A , Bennett David A , Schneider Julie A 
Published: March 2024

AbstractINTRODUCTIONThis study investigates the relationship between microglia inflammation in the hippocampus, brain pathologies, and cognitive decline.METHODSParticipants underwent annual clinical evaluations and agreed to brain donation. Neuropathologic evaluations quantified microglial burden in the hippocampus, amyloid beta (Aβ), tau tangles, and limbic age‐related transactive response DNA‐binding protein 43 (TDP‐43) encephalopathy neuropathologic changes (LATE‐NC), and other common brain pathologies. Mixed‐effect and linear regression models examined the association of microglia with a decline in global and domain‐specific cognitive measures, and separately with brain pathologies. Path analyses estimated direct and indirect effects of microglia on global cognition.RESULTHippocampal microglia were associated with a faster decline in global cognition, specifically in episodic memory, semantic memory, and perceptual speed. Tau tangles and LATE‐NC were independently associated with microglia. Other pathologies, including Aβ, were not related. Regional hippocampal burden of tau tangles and TDP‐43 accounted for half of the association of microglia with cognitive decline.DISCUSSIONMicroglia inflammation in the hippocampus contributes to cognitive decline. Tau tangles and LATE‐NC partially mediate this association.
The Impact of Metagenomics on Biocatalysis
Authors: Hogg Bethany N. , Schnepel Christian , Finnigan James D. , Charnock Simon J. , Hayes Martin A. , Turner Nicholas J. 
Published: March 2024

AbstractIn the ever‐growing demand for sustainable ways to produce high‐value small molecules, biocatalysis has come to the forefront of greener routes to these chemicals. As such, the need to constantly find and optimise suitable biocatalysts for specific transformations has never been greater. Metagenome mining has been shown to rapidly expand the toolkit of promiscuous enzymes needed for new transformations, without requiring protein engineering steps. If protein engineering is needed, the metagenomic candidate can often provide a better starting point for engineering than a previously discovered enzyme on the open database or from literature, for instance. In this review, we highlight where metagenomics has made substantial impact on the area of biocatalysis in recent years. We review the discovery of enzymes in previously unexplored or ‘hidden’ sequence space, leading to the characterisation of enzymes with enhanced properties that originate from natural selection pressures in native environments.
Degradation kinetics of PLA compounds with castor oil
Authors: Dantas Lorena , Araújo Amanda , Nicácio Pedro , Severo Amanda , Albuquerque Ananda , Souza Matheus , Luna Carlos , Araújo Edcleide , Wellen Renate 
Published: March 2024

AbstractPoly (lactic acid) (PLA) compounds with castor oil (CO) and epoxidized castor oil (ECO) were produced via formic acid, with levels of 5% CO, 3 and 5% ECO. The contribution of this study lies in the detailed analysis of thermal degradation and degradation kinetics of PLA/CO and PLA/ECO. Chemical changes were evidenced by Fourier transform infrared (FTIR), thermal stability, and degradation kinetics were investigated by thermogravimetric analysis (TGA), using Friedman (FR), Ozawa–Flynn–Wall (OFW), Kissinger–Akahira–Sunose (KAS) and Vyazovkin (VZ) models. Results showed changes in FTIR spectra for PLA/CO and PLA/ECO. For PLA/5%CO and PLA/3%ECO, lower energy bonds formation were observed, resulting in modifications in the involved molecules and presence of CH type bonds in PLA/5%ECO. TGA analysis showed that PLA presented greater thermal stability compared with PLA/CO and PLA/ECO, with T5% = 306°C. The compounds 5% CO, 3 and 5% ECO exhibited lower degradation temperatures (298, 300, and 296°C), compared with PLA, as well as slower decomposition rates. Kinetic modeling using KAS and OFW models proved to be incapable of describing the degradation kinetics of PLA and its compounds. However, FR and VZ were considered adequate, with discrepancies varying between 7% to −4% and 9% to −3%, which showed higher (215, 185, 210, 189 KJ/mol) at α = 0.3 for PLA.